Chr	Start	End	Ref	Alt	MitImpact_id	Gene_symbol	OXPHOS_complex	Ensembl_gene_id	Ensembl_protein_id	Ensembl_transcript_id	Uniprot_name	Uniprot_id	Ncbi_gene_id	Ncbi_protein_id	Gene_position	AA_position	AA_ref	AA_alt	Codon_substitution	PhyloP_100V	PhastCons_100V	SiteVar	PolyPhen2	PolyPhen2_score	SIFT	SIFT_score	FatHmm	FatHmm_score	FatHmmW	FatHmmW_score	PROVEAN	PROVEAN_score	MutationAssessor	MutationAssessor_score	EFIN_SP	EFIN_SP_score	EFIN_HD	EFIN_HD_score	CADD	CADD_score	CADD_phred_score	VEST_pvalue	VEST_FDR	PANTHER	PANTHER_score	PhD-SNP	PhD-SNP_score	SNAP	SNAP_score	Meta-SNP	Meta-SNP_score	Meta-SNP_RI	CAROL	CAROL_score	Condel	Condel_score	COVEC_WMV	COVEC_WMV_score	MtoolBox	MtoolBox_DS	PolyPhen2_transf	PolyPhen2_transf_score	SIFT_transf	SIFT_transf_score	MutationAssessor_transf	MutationAssessor_transf_score	CHASM_pvalue	CHASM_FDR	MISTIC_coevo_sites	MISTIC_mean_MI_score	APOGEE_boost_consensus	APOGEE_boost_mean_prob	APOGEE_boost_mean	SNPDryad_score	MutationTaster	MutationTaster_score	DEOGEN_Score	dbSNP_150_id	ClinVar_Oct2017_CLINSIG	ClinVar_Oct2017_CLNDBN	ClinVar_Oct2017_CLNACC	ClinVar_Oct2017_CLNDSDB	Mitomap_Dec2016_Somatic_occurrence	COSMIC_79_id	CPD_candidate	CPD_freq	Mitomap_Allele	Mitomap_Phenotype	Mitomap_Homo	Mitomap_Het	Mitomap_Status	Mitomap_NRef
chrM	8527	8527	A	C	MI.1	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	1	1	M	L	Atg/Ctg	2,21	1	0	possibly_damaging	0,52	deleterious	0,02	neutral	4,7	neutral	0,88	neutral	-2,48	NA	NA	neutral	0,63	damaging	0,08	deleterious	3,93	23,5	0,38	0,65	disease	0,68	neutral	0,34	disease	0,63	disease	0,57	1	neutral	0,98	neutral	0,25	deleterious	3	deleterious	0,51	NA	NA	NA	NA	NA	NA	0,5	0,9	50	8,74	P	0,5	N	0,93	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8531	8531	A	T	MI.10	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	5	2	N	I	aAc/aTc	6,84	1	0	probably_damaging	0,99	neutral	0,57	neutral	4,65	neutral	-0,66	deleterious	-4,59	low_impact	1,4	neutral	0,86	neutral	0,52	deleterious	3,71	23,3	0,47	0,65	neutral	0,32	disease	0,53	neutral	0,27	disease	0,51	0	deleterious	0,99	neutral	0,29	neutral	-2	deleterious	0,66	low_impact	-2,65	medium_impact	0,36	medium_impact	0,1	0,42	0,9	41,59	7,23	N	0,5	N	1	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8572	8572	G	A	MI.100	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	46	16	G	S	Ggc/Agc	0,13	0,8	0,01	possibly_damaging	0,56	neutral	0,17	neutral	4,67	neutral	0,05	deleterious	-4,62	medium_impact	2,23	neutral	0,96	neutral	0,43	deleterious	3,5	23,1	0,38	0,65	disease	0,52	disease	0,8	neutral	0,44	disease	0,54	1	neutral	0,82	neutral	0,31	NA	0	deleterious	0,61	medium_impact	-0,86	medium_impact	-0,1	medium_impact	0,81	0,84	0,9	17,26	11,64	N	0,35	N	0,66	disease_causing	1	0,09	rs28502681	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8995	8995	G	A	MI.1000	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	469	157	A	T	Gcc/Acc	-1,26	0	0	probably_damaging	1	neutral	0,3	neutral	3,7	neutral	-1,55	deleterious	-2,93	low_impact	1,34	neutral	0,77	neutral	0,51	deleterious	4,34	24	0,43	0,65	neutral	0,43	disease	0,73	disease	0,58	disease	0,66	3	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,08	medium_impact	0,05	0,78	0,9	48,67	9	N	0,26	N	0,8	polymorphism	0,94	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15530	15530	T	G	MI.10000	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	784	262	L	V	Tta/Gta	-11,75	0	0,01	probably_damaging	0,92	neutral	0,56	neutral	2,73	neutral	-1,71	neutral	-2,17	high_impact	4,51	neutral	0,87	damaging	0,11	neutral	1,7	14,39	0,18	0,45	neutral	0,45	neutral	0,47	disease	0,65	neutral	0,49	0	neutral	0,91	neutral	0,32	deleterious	2	deleterious	0,67	low_impact	-1,72	medium_impact	0,28	high_impact	2,9	0,45	0,8	58,16	8,43	N	0,36	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15531	15531	T	G	MI.10001	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	785	262	L	W	tTa/tGa	-0,52	0	0	probably_damaging	1	neutral	0,2	neutral	2,6	deleterious	-5,26	deleterious	-4,42	high_impact	5,07	neutral	0,88	damaging	0,08	deleterious	3,82	23,4	0,04	0,35	disease	0,85	disease	0,53	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,1	high_impact	3,41	0,17	0,8	58,16	8,43	P	0,63	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15531	15531	T	C	MI.10002	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	785	262	L	S	tTa/tCa	-0,52	0	0	probably_damaging	1	neutral	0,42	neutral	2,66	neutral	-2,86	deleterious	-4,39	high_impact	4,26	neutral	0,85	damaging	0,08	deleterious	3,61	23,2	0,04	0,35	disease	0,65	disease	0,69	disease	0,64	disease	0,66	3	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,15	high_impact	2,67	0,19	0,8	58,16	8,43	N	0,32	N	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15532	15532	A	T	MI.10003	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	786	262	L	F	ttA/ttT	5,67	0,87	0	probably_damaging	0,99	neutral	0,72	neutral	2,67	neutral	-2,48	deleterious	-2,93	medium_impact	2,83	neutral	0,88	damaging	0,09	deleterious	3,3	22,9	0,09	0,35	neutral	0,33	disease	0,57	disease	0,58	disease	0,63	3	deleterious	0,99	neutral	0,37	deleterious	1	deleterious	0,74	low_impact	-2,59	medium_impact	0,44	medium_impact	1,38	0,4	0,8	58,16	8,43	N	0,36	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15532	15532	A	C	MI.10004	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	786	262	L	F	ttA/ttC	5,67	0,87	0	probably_damaging	0,99	neutral	0,72	neutral	2,67	neutral	-2,48	deleterious	-2,93	medium_impact	2,83	neutral	0,88	damaging	0,09	deleterious	3,14	22,6	0,09	0,35	neutral	0,33	disease	0,57	disease	0,58	disease	0,63	3	deleterious	0,99	neutral	0,37	deleterious	1	deleterious	0,74	low_impact	-2,59	medium_impact	0,44	medium_impact	1,38	0,4	0,8	58,16	8,43	N	0,36	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15533	15533	A	C	MI.10005	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	787	263	N	H	Aac/Cac	-2,12	0	0	possibly_damaging	0,64	neutral	0,54	neutral	3,13	neutral	-1,54	neutral	-0,9	medium_impact	2,29	neutral	0,94	neutral	0,33	neutral	1,79	14,9	0,23	0,45	disease	0,6	neutral	0,36	disease	0,59	disease	0,65	3	neutral	0,6	neutral	0,45	NA	0	deleterious	0,44	medium_impact	-0,96	medium_impact	0,26	medium_impact	0,89	0,17	0,8	51,58	8,47	N	0,29	N	0,77	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15533	15533	A	T	MI.10006	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	787	263	N	Y	Aac/Tac	-2,12	0	0	possibly_damaging	0,74	neutral	1	neutral	3,15	neutral	-2,29	neutral	-0,45	medium_impact	2,74	neutral	0,94	neutral	0,41	deleterious	2,34	18,44	0,12	0,4	disease	0,67	neutral	0,5	disease	0,58	disease	0,68	4	neutral	0,74	deleterious	0,63	NA	0	deleterious	0,58	low_impact	-1,16	high_impact	1,85	medium_impact	1,29	0,16	0,8	51,58	8,47	N	0,22	N	0,98	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15533	15533	A	G	MI.10007	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	787	263	N	D	Aac/Gac	-2,12	0	0	benign	0,06	neutral	0,2	neutral	3,15	neutral	-0,23	neutral	-0,83	medium_impact	2,54	neutral	0,91	neutral	0,37	neutral	1,04	10,89	0,3	0,45	neutral	0,46	neutral	0,36	disease	0,55	neutral	0,5	0	neutral	0,78	deleterious	0,57	neutral	-3	neutral	0,18	medium_impact	0,38	medium_impact	-0,1	medium_impact	1,11	0,22	0,8	51,58	8,47	N	0,43	N	0,91	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15534	15534	A	G	MI.10008	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	788	263	N	S	aAc/aGc	2	0,01	0	benign	0	neutral	0,4	neutral	3,2	neutral	0,33	neutral	0,13	neutral_impact	-0,07	neutral	0,98	neutral	0,93	neutral	-0,4	0,39	0,36	0,5	neutral	0,27	neutral	0,23	neutral	0,3	neutral	0,42	2	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	0,13	low_impact	-1,26	0,2	0,8	51,58	8,47	N	0,41	N	0,35	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15534	15534	A	C	MI.10009	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	788	263	N	T	aAc/aCc	2	0,01	0	benign	0,06	neutral	0,4	neutral	3,19	neutral	-0,52	neutral	0,6	low_impact	1,38	neutral	0,97	neutral	0,49	deleterious	0,46	7,14	0,18	0,45	neutral	0,42	neutral	0,41	neutral	0,26	neutral	0,48	0	neutral	0,56	deleterious	0,67	neutral	-6	neutral	0,17	medium_impact	0,38	medium_impact	0,13	medium_impact	0,06	0,28	0,8	51,58	8,47	N	0,38	N	0,72	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8996	8996	C	A	MI.1001	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	470	157	A	D	gCc/gAc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	3,61	deleterious	-3,98	deleterious	-3,81	medium_impact	3,02	neutral	0,76	neutral	0,43	deleterious	4,57	24,4	0,1	0,65	disease	0,72	disease	0,94	disease	0,69	disease	0,83	7	deleterious	1	neutral	0	deleterious	5	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	medium_impact	1,49	0,69	0,9	48,67	9	N	0,46	N	0,99	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15534	15534	A	T	MI.10010	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	788	263	N	I	aAc/aTc	2	0,01	0	possibly_damaging	0,6	neutral	0,4	neutral	3,23	neutral	-1,81	neutral	1,46	neutral_impact	0,08	neutral	0,92	neutral	0,59	deleterious	2,54	19,71	0,13	0,4	disease	0,54	neutral	0,41	neutral	0,27	disease	0,53	1	neutral	0,64	neutral	0,4	neutral	-3	neutral	0,39	medium_impact	-0,9	medium_impact	0,13	low_impact	-1,12	0,16	0,8	51,58	8,47	N	0,39	N	0,98	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15535	15535	C	A	MI.10011	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	789	263	N	K	aaC/aaA	-0,98	0	0,08	benign	0,15	neutral	0,29	neutral	3,21	neutral	1,19	neutral	-0,51	neutral_impact	0,39	neutral	0,93	neutral	0,35	deleterious	2,98	22,2	0,22	0,45	neutral	0,27	neutral	0,43	disease	0,57	neutral	0,49	0	neutral	0,66	deleterious	0,57	neutral	-6	neutral	0,23	medium_impact	-0,03	medium_impact	0,01	medium_impact	-0,84	0,34	0,8	51,58	8,47	N	0,33	N	0,93	polymorphism	1	0,01	rs28357371	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15535	15535	C	G	MI.10012	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	789	263	N	K	aaC/aaG	-0,98	0	0,08	benign	0,15	neutral	0,29	neutral	3,21	neutral	1,19	neutral	-0,51	neutral_impact	0,39	neutral	0,93	neutral	0,35	deleterious	2,56	19,83	0,22	0,45	neutral	0,27	neutral	0,43	disease	0,57	neutral	0,49	0	neutral	0,66	deleterious	0,57	neutral	-6	neutral	0,23	medium_impact	-0,03	medium_impact	0,01	medium_impact	-0,84	0,34	0,8	51,58	8,47	N	0,33	N	0,93	polymorphism	1	0,01	rs28357371	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15536	15536	A	G	MI.10013	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	790	264	T	A	Acc/Gcc	-7,17	0	0	benign	0	neutral	0,55	neutral	1,81	deleterious	-5,45	deleterious	-3,77	high_impact	4,07	neutral	0,98	damaging	0,16	neutral	1,56	13,63	0,13	0,4	disease	0,65	neutral	0,41	disease	0,8	disease	0,66	3	neutral	0,45	deleterious	0,78	neutral	-2	neutral	0,25	high_impact	2,07	medium_impact	0,27	high_impact	2,5	0,28	0,8	57,89	8,75	N	0,36	N	0,59	polymorphism	1	0,13	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15536	15536	A	C	MI.10014	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	790	264	T	P	Acc/Ccc	-7,17	0	0	benign	0,34	neutral	0,37	neutral	1,77	deleterious	-6,84	deleterious	-4,56	high_impact	5,3	neutral	0,95	damaging	0,06	deleterious	1,86	15,35	0,04	0,35	disease	0,88	disease	0,61	disease	0,73	disease	0,74	5	neutral	0,56	deleterious	0,52	neutral	-2	deleterious	0,63	medium_impact	-0,46	medium_impact	0,1	high_impact	3,62	0,35	0,8	57,89	8,75	P	0,55	P	0,95	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15536	15536	A	T	MI.10015	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	790	264	T	S	Acc/Tcc	-7,17	0	0	benign	0,03	neutral	0,38	neutral	1,97	deleterious	-3,36	deleterious	-3,02	high_impact	3,88	neutral	0,93	damaging	0,09	neutral	1,39	12,73	0,26	0,45	disease	0,57	neutral	0,49	disease	0,73	disease	0,67	3	neutral	0,59	deleterious	0,68	neutral	-2	neutral	0,28	medium_impact	0,68	medium_impact	0,11	high_impact	2,33	0,52	0,8	57,89	8,75	N	0,35	N	0,81	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15537	15537	C	T	MI.10016	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	791	264	T	I	aCc/aTc	4,52	0,99	0	benign	0,3	neutral	0,45	neutral	1,77	deleterious	-7,22	deleterious	-4,55	high_impact	5,3	neutral	0,93	damaging	0,11	deleterious	3,7	23,3	0,06	0,35	disease	0,91	disease	0,63	disease	0,79	disease	0,73	5	neutral	0,46	deleterious	0,58	neutral	-2	deleterious	0,58	medium_impact	-0,39	medium_impact	0,18	high_impact	3,62	0,52	0,8	57,89	8,75	P	0,65	P	0,83	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15537	15537	C	A	MI.10017	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	791	264	T	N	aCc/aAc	4,52	0,99	0	benign	0,34	neutral	0,36	neutral	1,79	deleterious	-5,9	deleterious	-3,79	high_impact	4,96	neutral	0,93	damaging	0,09	deleterious	2,07	16,67	0,21	0,45	disease	0,87	disease	0,68	disease	0,81	disease	0,75	5	neutral	0,57	deleterious	0,51	neutral	-2	deleterious	0,53	medium_impact	-0,46	medium_impact	0,09	high_impact	3,31	0,39	0,8	57,89	8,75	P	0,66	P	0,84	polymorphism	1	0,27	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15537	15537	C	G	MI.10018	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	791	264	T	S	aCc/aGc	4,52	0,99	0	benign	0,03	neutral	0,38	neutral	1,97	deleterious	-3,36	deleterious	-3,02	high_impact	3,88	neutral	0,93	damaging	0,09	neutral	1,78	14,87	0,26	0,45	disease	0,57	neutral	0,49	disease	0,73	disease	0,67	3	neutral	0,59	deleterious	0,68	neutral	-2	neutral	0,28	medium_impact	0,68	medium_impact	0,11	high_impact	2,33	0,52	0,8	57,89	8,75	P	0,54	P	0,81	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15539	15539	C	A	MI.10019	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	793	265	P	T	Cct/Act	-13,35	0	0	probably_damaging	1	neutral	0,45	neutral	1,14	deleterious	-7,47	deleterious	-5,97	high_impact	4,42	neutral	0,92	neutral	0,45	deleterious	3,65	23,2	0,05	0,35	disease	0,67	disease	0,84	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,18	high_impact	2,82	0,42	0,8	59,74	8,69	N	0,43	N	0,96	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8996	8996	C	T	MI.1002	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	470	157	A	V	gCc/gTc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	3,65	neutral	-2,41	deleterious	-3,3	medium_impact	2,67	neutral	0,82	neutral	0,56	deleterious	4,63	24,5	0,4	0,65	disease	0,73	disease	0,84	disease	0,59	disease	0,74	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,86	low_impact	-3,6	low_impact	-1,4	medium_impact	1,19	0,76	0,9	48,67	9	P	0,51	P	0,75	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15539	15539	C	G	MI.10020	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	793	265	P	A	Cct/Gct	-13,35	0	0	probably_damaging	0,99	neutral	0,5	neutral	1,15	deleterious	-6,7	deleterious	-5,98	high_impact	5,31	neutral	0,94	neutral	0,49	neutral	1,57	13,68	0,06	0,35	disease	0,62	disease	0,63	disease	0,75	disease	0,72	4	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	0,22	high_impact	3,63	0,56	0,8	59,74	8,69	P	0,62	P	0,84	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15539	15539	C	T	MI.10021	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	793	265	P	S	Cct/Tct	-13,35	0	0	probably_damaging	1	neutral	0,39	neutral	1,16	deleterious	-6,46	deleterious	-5,98	high_impact	4,76	neutral	0,93	neutral	0,45	deleterious	3,83	23,4	0,05	0,35	disease	0,63	disease	0,79	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,12	high_impact	3,13	0,23	0,8	59,74	8,69	P	0,6	P	0,9	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15540	15540	C	T	MI.10022	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	794	265	P	L	cCt/cTt	4,29	0,99	0	probably_damaging	1	neutral	0,64	neutral	1,14	deleterious	-7,35	deleterious	-7,5	high_impact	4,28	neutral	0,93	neutral	0,37	deleterious	4,38	24,1	0,05	0,35	disease	0,66	disease	0,85	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,36	high_impact	2,69	0,62	0,8	59,74	8,69	N	0,49	N	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15540	15540	C	G	MI.10023	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	794	265	P	R	cCt/cGt	4,29	0,99	0	probably_damaging	1	neutral	0,33	neutral	1,13	deleterious	-8,18	deleterious	-6,73	high_impact	4,62	neutral	0,93	neutral	0,35	deleterious	3,66	23,2	0,03	0,35	disease	0,69	disease	0,86	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,06	high_impact	3	0,31	0,8	59,74	8,69	P	0,58	P	0,8	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15540	15540	C	A	MI.10024	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	794	265	P	H	cCt/cAt	4,29	0,99	0	probably_damaging	1	neutral	0,54	neutral	1,12	deleterious	-9,43	deleterious	-6,75	high_impact	5,31	neutral	0,88	neutral	0,32	deleterious	3,99	23,6	0,04	0,35	disease	0,8	disease	0,82	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,26	high_impact	3,63	0,29	0,8	59,74	8,69	P	0,63	P	0,71	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15542	15542	C	T	MI.10025	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	796	266	P	S	Ccc/Tcc	-20	0	0	probably_damaging	1	neutral	0,39	neutral	3,11	neutral	-0,69	deleterious	-5,51	medium_impact	3,19	neutral	0,81	neutral	0,48	deleterious	3,63	23,2	0,21	0,45	neutral	0,37	disease	0,73	neutral	0,46	neutral	0,48	0	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,75	low_impact	-3,53	medium_impact	0,12	medium_impact	1,7	0,13	0,8	17,37	23,08	N	0,28	N	0,9	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15542	15542	C	G	MI.10026	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	796	266	P	A	Ccc/Gcc	-20	0	0	probably_damaging	0,98	neutral	0,51	neutral	3,21	neutral	0,58	deleterious	-5,42	low_impact	1,62	neutral	0,88	neutral	0,67	deleterious	0,34	6,12	0,16	0,45	neutral	0,25	disease	0,5	neutral	0,33	neutral	0,4	2	neutral	0,97	neutral	0,27	neutral	-2	deleterious	0,7	low_impact	-2,31	medium_impact	0,23	medium_impact	0,28	0,62	0,8	17,37	23,08	N	0,36	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15542	15542	C	A	MI.10027	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	796	266	P	T	Ccc/Acc	-20	0	0	probably_damaging	1	neutral	0,41	neutral	3,13	neutral	-1,08	deleterious	-5,45	medium_impact	2,27	neutral	0,81	neutral	0,44	deleterious	3,42	23	0,18	0,45	neutral	0,41	disease	0,74	neutral	0,26	neutral	0,46	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,75	low_impact	-3,53	medium_impact	0,14	medium_impact	0,87	0,58	0,8	17,37	23,08	N	0,28	N	0,96	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15543	15543	C	G	MI.10028	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	797	266	P	R	cCc/cGc	2,69	0,86	0	probably_damaging	1	neutral	0,34	neutral	3,1	neutral	-1,58	deleterious	-6,3	high_impact	3,94	neutral	0,83	neutral	0,33	deleterious	3,67	23,3	0,08	0,35	neutral	0,43	disease	0,84	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,07	high_impact	2,38	0,34	0,8	17,37	23,08	N	0,36	N	0,8	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15543	15543	C	T	MI.10029	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	797	266	P	L	cCc/cTc	2,69	0,86	0	probably_damaging	1	neutral	0,67	neutral	3,22	neutral	-1,15	deleterious	-6,87	medium_impact	2,17	neutral	0,88	neutral	0,39	deleterious	4,33	24	0,14	0,4	neutral	0,29	disease	0,81	neutral	0,36	disease	0,6	2	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,75	low_impact	-3,53	medium_impact	0,39	medium_impact	0,78	0,62	0,8	17,37	23,08	N	0,25	N	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8996	8996	C	G	MI.1003	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	470	157	A	G	gCc/gGc	9,15	1	0	probably_damaging	0,99	neutral	1	neutral	3,84	neutral	-0,39	neutral	-0,45	neutral_impact	-1,14	neutral	0,81	neutral	0,59	neutral	1,33	12,42	0,25	0,65	neutral	0,31	neutral	0,16	neutral	0,29	neutral	0,23	5	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,68	low_impact	-2,65	high_impact	1,98	low_impact	-2,07	0,79	0,9	48,67	9	N	0,44	N	0,86	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15543	15543	C	A	MI.10030	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	797	266	P	H	cCc/cAc	2,69	0,86	0	probably_damaging	1	neutral	0,55	neutral	3,08	neutral	-2,47	deleterious	-6,32	high_impact	4,08	neutral	0,78	neutral	0,31	deleterious	4,06	23,7	0,1	0,4	disease	0,59	disease	0,81	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,27	high_impact	2,51	0,25	0,8	17,37	23,08	N	0,27	N	0,71	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15545	15545	C	G	MI.10031	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	799	267	H	D	Cac/Gac	-11,98	0	0	probably_damaging	0,99	neutral	0,2	neutral	2,67	neutral	-2,37	deleterious	-6,71	high_impact	4,24	neutral	0,92	neutral	0,34	deleterious	2,29	18,13	0,05	0,35	neutral	0,48	disease	0,81	disease	0,82	disease	0,76	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	-0,1	high_impact	2,66	0,2	0,8	57,89	8,59	N	0,5	N	0,98	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15545	15545	C	A	MI.10032	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	799	267	H	N	Cac/Aac	-11,98	0	0	probably_damaging	0,98	neutral	0,31	neutral	2,66	neutral	-2,61	deleterious	-5,21	high_impact	4,24	neutral	0,93	neutral	0,42	deleterious	2,23	17,73	0,16	0,45	neutral	0,48	disease	0,85	disease	0,79	disease	0,74	5	deleterious	0,98	neutral	0,17	deleterious	2	deleterious	0,78	low_impact	-2,31	medium_impact	0,03	high_impact	2,66	0,17	0,8	57,89	8,59	N	0,51	P	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15545	15545	C	T	MI.10033	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	799	267	H	Y	Cac/Tac	-11,98	0	0	probably_damaging	0,97	neutral	1	neutral	2,6	deleterious	-4,64	deleterious	-4,47	high_impact	4,72	neutral	0,94	neutral	0,37	deleterious	2,04	16,47	0,09	0,35	disease	0,72	disease	0,85	disease	0,75	disease	0,75	5	neutral	0,97	deleterious	0,52	deleterious	2	deleterious	0,83	low_impact	-2,14	high_impact	1,85	high_impact	3,09	0,17	0,8	57,89	8,59	P	0,64	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15546	15546	A	T	MI.10034	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	800	267	H	L	cAc/cTc	7,04	1	0	probably_damaging	0,97	neutral	0,65	neutral	2,62	deleterious	-3,42	deleterious	-8,2	high_impact	4,03	neutral	0,95	neutral	0,37	deleterious	2,25	17,81	0,04	0,35	disease	0,55	disease	0,89	disease	0,78	disease	0,77	5	neutral	0,97	neutral	0,34	deleterious	2	deleterious	0,81	low_impact	-2,14	medium_impact	0,37	high_impact	2,47	0,15	0,8	57,89	8,59	P	0,6	P	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15546	15546	A	G	MI.10035	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	800	267	H	R	cAc/cGc	7,04	1	0	probably_damaging	0,97	neutral	0,35	neutral	2,65	neutral	-2,79	deleterious	-5,96	high_impact	4,72	neutral	0,94	neutral	0,32	neutral	1,34	12,46	0,06	0,35	neutral	0,47	disease	0,86	disease	0,77	disease	0,74	5	neutral	0,97	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-2,14	medium_impact	0,08	high_impact	3,09	0,16	0,8	57,89	8,59	P	0,73	P	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15546	15546	A	C	MI.10036	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	800	267	H	P	cAc/cCc	7,04	1	0	probably_damaging	0,99	neutral	0,21	neutral	2,6	deleterious	-4,19	deleterious	-7,47	high_impact	5,28	neutral	0,94	damaging	0,27	neutral	1,68	14,29	0,03	0,35	neutral	0,48	disease	0,87	disease	0,76	disease	0,74	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,83	low_impact	-2,59	medium_impact	-0,09	high_impact	3,6	0,12	0,8	57,89	8,59	P	0,69	P	0,99	polymorphism	1	0,12	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15547	15547	C	A	MI.10037	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	801	267	H	Q	caC/caA	8,42	1	0	probably_damaging	0,98	neutral	0,29	neutral	2,65	neutral	-2,65	deleterious	-5,96	high_impact	4,58	neutral	0,95	neutral	0,35	deleterious	2,25	17,84	0,09	0,35	neutral	0,37	disease	0,82	disease	0,77	disease	0,74	5	deleterious	0,98	neutral	0,16	deleterious	2	deleterious	0,76	low_impact	-2,31	medium_impact	0,01	high_impact	2,97	0,24	0,8	57,89	8,59	P	0,62	P	0,94	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15547	15547	C	G	MI.10038	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	801	267	H	Q	caC/caG	8,42	1	0	probably_damaging	0,98	neutral	0,29	neutral	2,65	neutral	-2,65	deleterious	-5,96	high_impact	4,58	neutral	0,95	neutral	0,35	deleterious	1,85	15,28	0,09	0,35	neutral	0,37	disease	0,82	disease	0,77	disease	0,74	5	deleterious	0,98	neutral	0,16	deleterious	2	deleterious	0,76	low_impact	-2,31	medium_impact	0,01	high_impact	2,97	0,24	0,8	57,89	8,59	P	0,61	P	0,94	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15548	15548	A	T	MI.10039	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	802	268	I	F	Atc/Ttc	-5,33	0	0	probably_damaging	0,99	neutral	0,7	neutral	1,98	deleterious	-5,6	deleterious	-2,93	high_impact	4,79	neutral	0,95	damaging	0,1	deleterious	2,06	16,61	0,06	0,35	disease	0,86	disease	0,82	disease	0,78	disease	0,8	6	deleterious	0,98	neutral	0,36	deleterious	2	deleterious	0,85	low_impact	-2,59	medium_impact	0,42	high_impact	3,16	0,54	0,8	58,42	8,75	P	0,69	P	0,97	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8998	8998	G	A	MI.1004	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	472	158	V	M	Gta/Ata	-10,98	0	0	possibly_damaging	0,55	deleterious	0,01	neutral	3,62	neutral	-2,61	deleterious	-2,65	medium_impact	3,32	neutral	0,89	neutral	0,65	deleterious	3,41	23	0,4	0,65	disease	0,64	disease	0,86	disease	0,55	disease	0,69	4	deleterious	0,99	neutral	0,23	deleterious	4	deleterious	0,57	medium_impact	-0,84	medium_impact	-0,84	medium_impact	1,75	0,85	0,9	48,67	8,64	N	0,46	N	0,96	polymorphism	0,6	0,12	rs376792657	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15548	15548	A	G	MI.10040	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	802	268	I	V	Atc/Gtc	-5,33	0	0	possibly_damaging	0,81	neutral	0,5	neutral	2,2	neutral	-2,47	neutral	-0,73	high_impact	4,29	neutral	0,95	damaging	0,13	neutral	1,14	11,42	0,29	0,45	neutral	0,45	neutral	0,49	disease	0,69	disease	0,59	2	neutral	0,79	neutral	0,35	deleterious	1	deleterious	0,49	low_impact	-1,32	medium_impact	0,22	high_impact	2,7	0,36	0,8	58,42	8,75	N	0,37	N	0,83	polymorphism	1	0,06	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15548	15548	A	C	MI.10041	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	802	268	I	L	Atc/Ctc	-5,33	0	0	probably_damaging	0,92	neutral	0,65	neutral	2,11	deleterious	-3,21	neutral	-1,47	high_impact	4,64	neutral	0,96	damaging	0,09	deleterious	1,89	15,51	0,15	0,4	disease	0,59	disease	0,69	disease	0,74	disease	0,73	5	neutral	0,91	neutral	0,37	deleterious	2	deleterious	0,58	low_impact	-1,72	medium_impact	0,37	high_impact	3,02	0,48	0,8	58,42	8,75	N	0,45	N	0,88	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15549	15549	T	A	MI.10042	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	803	268	I	N	aTc/aAc	6,81	1	0	probably_damaging	1	neutral	0,31	neutral	1,96	deleterious	-7,3	deleterious	-5,14	high_impact	5,33	neutral	0,94	damaging	0,1	deleterious	4,24	23,9	0,06	0,35	disease	0,95	disease	0,88	disease	0,77	disease	0,84	7	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,03	high_impact	3,65	0,44	0,8	58,42	8,75	P	0,77	P	0,99	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15549	15549	T	C	MI.10043	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	803	268	I	T	aTc/aCc	6,81	1	0	probably_damaging	0,99	neutral	0,39	neutral	1,99	deleterious	-5,09	deleterious	-3,65	high_impact	5,33	neutral	0,94	damaging	0,09	deleterious	1,9	15,59	0,04	0,35	disease	0,85	disease	0,83	disease	0,76	disease	0,8	6	deleterious	0,99	neutral	0,2	deleterious	2	deleterious	0,86	low_impact	-2,59	medium_impact	0,12	high_impact	3,65	0,41	0,8	58,42	8,75	P	0,76	P	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15549	15549	T	G	MI.10044	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	803	268	I	S	aTc/aGc	6,81	1	0	probably_damaging	0,99	neutral	0,4	neutral	1,97	deleterious	-6,23	deleterious	-4,38	high_impact	5,33	neutral	0,94	damaging	0,1	deleterious	4,01	23,6	0,03	0,35	disease	0,91	disease	0,86	disease	0,77	disease	0,82	6	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-2,59	medium_impact	0,13	high_impact	3,65	0,3	0,8	58,42	8,75	P	0,79	P	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15550	15550	C	A	MI.10045	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	804	268	I	M	atC/atA	7,27	1	0	probably_damaging	1	neutral	0,22	neutral	2	deleterious	-4,91	neutral	-2,2	high_impact	4,43	neutral	0,95	damaging	0,09	deleterious	2,26	17,92	0,11	0,4	disease	0,83	disease	0,65	disease	0,67	disease	0,63	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	-0,08	high_impact	2,83	0,61	0,8	58,42	8,75	P	0,55	P	0,83	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15550	15550	C	G	MI.10046	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	804	268	I	M	atC/atG	7,27	1	0	probably_damaging	1	neutral	0,22	neutral	2	deleterious	-4,91	neutral	-2,2	high_impact	4,43	neutral	0,95	damaging	0,09	neutral	1,78	14,87	0,11	0,4	disease	0,83	disease	0,65	disease	0,67	disease	0,63	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	-0,08	high_impact	2,83	0,61	0,8	58,42	8,75	P	0,55	P	0,83	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15551	15551	A	G	MI.10047	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	805	269	K	E	Aag/Gag	-5,1	0	0	probably_damaging	0,99	neutral	0,29	neutral	3,05	neutral	-0,88	neutral	-2,16	medium_impact	3,28	neutral	0,92	damaging	0,14	deleterious	3,79	23,4	0,1	0,4	neutral	0,43	disease	0,84	disease	0,75	disease	0,77	5	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,81	low_impact	-2,59	medium_impact	0,01	medium_impact	1,79	0,57	0,8	56,58	8,55	N	0,38	N	0,95	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15551	15551	A	C	MI.10048	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	805	269	K	Q	Aag/Cag	-5,1	0	0	probably_damaging	0,99	neutral	0,29	neutral	3,11	neutral	-0,09	neutral	-1,68	low_impact	1,07	neutral	0,9	damaging	0,13	deleterious	1,93	15,79	0,22	0,45	neutral	0,43	disease	0,61	neutral	0,36	neutral	0,43	1	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,75	low_impact	-2,59	medium_impact	0,01	medium_impact	-0,22	0,36	0,8	56,58	8,55	N	0,34	N	0,93	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15552	15552	A	C	MI.10049	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	806	269	K	T	aAg/aCg	6,81	1	0	probably_damaging	1	neutral	0,38	neutral	3,05	neutral	-0,97	deleterious	-3,66	high_impact	4	neutral	0,91	damaging	0,14	deleterious	3,71	23,3	0,05	0,35	neutral	0,42	disease	0,86	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,11	high_impact	2,44	0,17	0,8	56,58	8,55	P	0,57	P	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8998	8998	G	C	MI.1005	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	472	158	V	L	Gta/Cta	-10,98	0	0	benign	0,07	neutral	0,15	neutral	4,17	neutral	0,61	deleterious	-2,62	low_impact	1,55	neutral	0,75	neutral	0,56	neutral	1,8	14,97	0,32	0,65	neutral	0,4	disease	0,81	neutral	0,35	neutral	0,49	0	neutral	0,84	deleterious	0,54	neutral	-6	neutral	0,26	medium_impact	0,31	medium_impact	-0,13	medium_impact	0,23	0,65	0,9	48,67	8,64	N	0,42	N	0,7	polymorphism	0,64	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15552	15552	A	T	MI.10050	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	806	269	K	M	aAg/aTg	6,81	1	0	probably_damaging	1	neutral	0,2	neutral	3,02	neutral	-2,25	deleterious	-3,34	high_impact	4,14	neutral	0,91	damaging	0,15	deleterious	4,13	23,8	0,05	0,35	disease	0,55	disease	0,78	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	-0,1	high_impact	2,57	0,13	0,8	56,58	8,55	P	0,57	P	0,67	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15553	15553	G	C	MI.10051	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	807	269	K	N	aaG/aaC	8,42	1	0	probably_damaging	1	neutral	0,28	neutral	3,01	neutral	-1,75	deleterious	-3	high_impact	4,7	neutral	0,88	damaging	0,13	deleterious	3,94	23,5	0,23	0,45	disease	0,52	disease	0,85	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0	high_impact	3,07	0,34	0,8	56,58	8,55	P	0,65	P	0,84	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15553	15553	G	T	MI.10052	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	807	269	K	N	aaG/aaT	8,42	1	0	probably_damaging	1	neutral	0,28	neutral	3,01	neutral	-1,75	deleterious	-3	high_impact	4,7	neutral	0,88	damaging	0,13	deleterious	4,05	23,7	0,23	0,45	disease	0,52	disease	0,85	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0	high_impact	3,07	0,34	0,8	56,58	8,55	P	0,65	P	0,84	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15554	15554	C	A	MI.10053	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	808	270	P	T	Ccc/Acc	0,4	0,98	0	probably_damaging	1	neutral	0,39	neutral	0,42	deleterious	-8,64	deleterious	-5,8	high_impact	5,34	neutral	0,92	damaging	0,11	deleterious	3,85	23,4	0,06	0,35	disease	0,72	disease	0,85	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,12	high_impact	3,66	0,55	0,8	58,68	8,76	P	0,61	P	0,96	polymorphism	1	0,17	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15554	15554	C	T	MI.10054	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	808	270	P	S	Ccc/Tcc	0,4	0,98	0	probably_damaging	1	neutral	0,4	neutral	0,43	deleterious	-8,2	deleterious	-5,8	high_impact	4,8	neutral	0,93	damaging	0,1	deleterious	3,85	23,4	0,07	0,35	neutral	0,45	disease	0,81	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,13	high_impact	3,17	0,22	0,8	58,68	8,76	P	0,6	P	0,9	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15554	15554	C	G	MI.10055	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	808	270	P	A	Ccc/Gcc	0,4	0,98	0	probably_damaging	0,99	neutral	0,51	neutral	0,44	deleterious	-7,91	deleterious	-5,79	high_impact	5,34	neutral	0,94	damaging	0,15	deleterious	2,84	21,6	0,07	0,35	neutral	0,47	disease	0,67	disease	0,7	disease	0,71	4	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,78	low_impact	-2,59	medium_impact	0,23	high_impact	3,66	0,63	0,8	58,68	8,76	P	0,58	P	0,84	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15555	15555	C	A	MI.10056	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	809	270	P	H	cCc/cAc	5,44	1	0	probably_damaging	1	neutral	0,53	neutral	0,41	deleterious	-10,26	deleterious	-6,55	high_impact	5,34	neutral	0,91	damaging	0,09	deleterious	4,06	23,7	0,05	0,35	disease	0,93	disease	0,85	disease	0,79	disease	0,86	7	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,25	high_impact	3,66	0,28	0,8	58,68	8,76	P	0,68	P	0,71	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15555	15555	C	G	MI.10057	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	809	270	P	R	cCc/cGc	5,44	1	0	probably_damaging	1	neutral	0,34	neutral	0,42	deleterious	-9,21	deleterious	-6,55	high_impact	5,34	neutral	0,93	damaging	0,08	deleterious	3,66	23,2	0,03	0,35	disease	0,85	disease	0,89	disease	0,81	disease	0,83	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,07	high_impact	3,66	0,28	0,8	58,68	8,76	P	0,7	P	0,8	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15555	15555	C	T	MI.10058	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	809	270	P	L	cCc/cTc	5,44	1	0	probably_damaging	1	neutral	0,64	neutral	0,42	deleterious	-9,09	deleterious	-7,29	high_impact	5,34	neutral	0,94	damaging	0,07	deleterious	4,48	24,3	0,05	0,35	disease	0,87	disease	0,87	disease	0,68	disease	0,78	6	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,36	high_impact	3,66	0,55	0,8	58,68	8,76	P	0,69	P	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15557	15557	G	A	MI.10059	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	811	271	E	K	Gaa/Aaa	-1,67	0	0	probably_damaging	1	neutral	0,3	neutral	2,32	deleterious	-4,18	deleterious	-2,81	high_impact	4,56	neutral	0,87	damaging	0,08	deleterious	4,42	24,2	0,06	0,35	disease	0,75	disease	0,88	disease	0,8	disease	0,78	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,02	high_impact	2,95	0,58	0,8	58,16	8,82	N	0,57	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8998	8998	G	T	MI.1006	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	472	158	V	L	Gta/Tta	-10,98	0	0	benign	0,07	neutral	0,15	neutral	4,17	neutral	0,61	deleterious	-2,62	low_impact	1,55	neutral	0,75	neutral	0,56	deleterious	1,9	15,6	0,32	0,65	neutral	0,4	disease	0,81	neutral	0,35	neutral	0,49	0	neutral	0,84	deleterious	0,54	neutral	-6	neutral	0,26	medium_impact	0,31	medium_impact	-0,13	medium_impact	0,23	0,65	0,9	48,67	8,64	N	0,42	N	0,7	polymorphism	0,64	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15557	15557	G	C	MI.10060	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	811	271	E	Q	Gaa/Caa	-1,67	0	0	probably_damaging	1	neutral	0,3	neutral	2,31	deleterious	-4,46	neutral	-2,1	high_impact	4,56	neutral	0,85	damaging	0,11	deleterious	3,33	22,9	0,14	0,4	disease	0,79	disease	0,79	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,02	high_impact	2,95	0,62	0,8	58,16	8,82	N	0,55	P	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15558	15558	A	G	MI.10061	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	812	271	E	G	gAa/gGa	5,9	1	0	probably_damaging	1	neutral	0,33	neutral	2,28	deleterious	-5,67	deleterious	-4,91	high_impact	5,25	neutral	0,92	damaging	0,14	deleterious	4,33	24	0,04	0,35	disease	0,83	disease	0,79	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,06	high_impact	3,57	0,27	0,8	58,16	8,82	P	0,77	P	0,77	polymorphism	1	0,25	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15558	15558	A	T	MI.10062	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	812	271	E	V	gAa/gTa	5,9	1	0	probably_damaging	1	neutral	0,5	neutral	2,31	deleterious	-4,46	deleterious	-4,91	medium_impact	3,03	neutral	0,86	damaging	0,12	deleterious	4,2	23,9	0,03	0,35	disease	0,88	disease	0,89	disease	0,79	disease	0,82	6	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,91	low_impact	-3,53	medium_impact	0,22	medium_impact	1,56	0,38	0,8	58,16	8,82	N	0,57	P	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15558	15558	A	C	MI.10063	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	812	271	E	A	gAa/gCa	5,9	1	0	probably_damaging	1	neutral	0,53	neutral	2,3	deleterious	-4,56	deleterious	-4,19	high_impact	5,25	neutral	0,87	damaging	0,15	deleterious	3,68	23,3	0,05	0,35	disease	0,79	disease	0,75	disease	0,78	disease	0,78	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,25	high_impact	3,57	0,36	0,8	58,16	8,82	P	0,77	P	0,82	polymorphism	1	0,15	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15559	15559	A	C	MI.10064	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	813	271	E	D	gaA/gaC	6,81	1	0	probably_damaging	0,99	neutral	0,21	neutral	2,52	neutral	-2,1	neutral	-2,11	high_impact	4,91	neutral	0,83	damaging	0,1	deleterious	2,2	17,49	0,22	0,45	disease	0,67	disease	0,75	disease	0,74	disease	0,73	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-2,59	medium_impact	-0,09	high_impact	3,26	0,55	0,8	58,16	8,82	P	0,77	P	0,91	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15559	15559	A	T	MI.10065	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	813	271	E	D	gaA/gaT	6,81	1	0	probably_damaging	0,99	neutral	0,21	neutral	2,52	neutral	-2,1	neutral	-2,11	high_impact	4,91	neutral	0,83	damaging	0,1	deleterious	2,23	17,73	0,22	0,45	disease	0,67	disease	0,75	disease	0,74	disease	0,73	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-2,59	medium_impact	-0,09	high_impact	3,26	0,55	0,8	58,16	8,82	P	0,77	P	0,91	polymorphism	1	0,04	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15560	15560	T	G	MI.10066	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	814	272	W	G	Tga/Gga	-0,29	0,24	0	benign	0	neutral	0,33	neutral	0,15	deleterious	-11,11	deleterious	-9,07	high_impact	5,34	neutral	0,81	damaging	0,13	deleterious	3,79	23,4	0,03	0,35	disease	0,92	disease	0,86	disease	0,75	disease	0,84	7	neutral	0,67	deleterious	0,67	neutral	-2	neutral	0,33	high_impact	2,07	medium_impact	0,06	high_impact	3,66	0,07	0,8	57,63	8,71	N	0,5	N	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15560	15560	T	C	MI.10067	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	814	272	W	R	Tga/Cga	-0,29	0,24	0	possibly_damaging	0,9	neutral	0,35	neutral	0,15	deleterious	-10,59	deleterious	-9,77	high_impact	4,8	neutral	0,78	damaging	0,06	deleterious	3,68	23,3	0,02	0,35	disease	0,91	disease	0,92	disease	0,79	disease	0,86	7	neutral	0,91	neutral	0,23	deleterious	1	deleterious	0,87	low_impact	-1,62	medium_impact	0,08	high_impact	3,17	0,08	0,8	57,63	8,71	P	0,52	P	0,99	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15561	15561	G	C	MI.10068	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	815	272	W	S	tGa/tCa	7,27	1	0	possibly_damaging	0,48	neutral	0,4	neutral	0,15	deleterious	-11,07	deleterious	-9,74	high_impact	5	neutral	0,85	damaging	0,09	deleterious	3,96	23,6	0,03	0,35	disease	0,89	disease	0,91	disease	0,74	disease	0,82	6	neutral	0,57	neutral	0,46	deleterious	1	deleterious	0,7	medium_impact	-0,7	medium_impact	0,13	high_impact	3,35	0,06	0,8	57,63	8,71	P	0,55	P	0,99	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15561	15561	G	T	MI.10069	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	815	272	W	L	tGa/tTa	7,27	1	0	possibly_damaging	0,64	neutral	0,65	neutral	0,17	deleterious	-8,72	deleterious	-9,07	high_impact	5	neutral	0,85	damaging	0,07	deleterious	4,16	23,8	0,03	0,35	disease	0,66	disease	0,88	disease	0,74	disease	0,77	5	neutral	0,57	deleterious	0,51	deleterious	1	deleterious	0,75	medium_impact	-0,96	medium_impact	0,37	high_impact	3,35	0,08	0,8	57,63	8,71	P	0,6	P	0,99	polymorphism	1	0,27	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	8999	8999	T	G	MI.1007	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	473	158	V	G	gTa/gGa	2,44	0,99	0	benign	0,11	deleterious	0	neutral	3,55	deleterious	-6,14	deleterious	-6,28	high_impact	4,29	neutral	0,89	neutral	0,66	deleterious	2,03	16,38	0,15	0,65	disease	0,96	disease	0,88	disease	0,64	disease	0,82	6	deleterious	1	neutral	0,45	deleterious	2	neutral	0,37	medium_impact	0,11	low_impact	-1,4	high_impact	2,58	0,42	0,9	48,67	8,64	N	0,47	N	0,93	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15562	15562	A	C	MI.10070	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	816	272	W	C	tgA/tgC	7,27	1	0,01	probably_damaging	0,95	neutral	0,18	neutral	0,15	deleterious	-12,17	deleterious	-9,09	high_impact	5,34	neutral	0,83	damaging	0,05	deleterious	4,12	23,8	0,03	0,35	disease	0,95	disease	0,9	disease	0,79	disease	0,84	7	neutral	0,97	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-1,92	medium_impact	-0,14	high_impact	3,66	0,13	0,8	57,63	8,71	P	0,53	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15562	15562	A	T	MI.10071	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	816	272	W	C	tgA/tgT	7,27	1	0,01	probably_damaging	0,95	neutral	0,18	neutral	0,15	deleterious	-12,17	deleterious	-9,09	high_impact	5,34	neutral	0,83	damaging	0,05	deleterious	4,19	23,8	0,03	0,35	disease	0,95	disease	0,9	disease	0,79	disease	0,84	7	neutral	0,97	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-1,92	medium_impact	-0,14	high_impact	3,66	0,13	0,8	57,63	8,71	P	0,53	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15563	15563	T	C	MI.10072	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	817	273	Y	H	Tat/Cat	0,17	0,92	0	probably_damaging	1	neutral	0,4	neutral	1,48	deleterious	-6,35	deleterious	-3,5	high_impact	5	neutral	0,85	damaging	0,09	deleterious	3,68	23,3	0,13	0,4	disease	0,87	disease	0,81	disease	0,82	disease	0,82	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,13	high_impact	3,35	0,17	0,8	56,84	8,69	P	0,73	P	0,98	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15563	15563	T	A	MI.10073	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	817	273	Y	N	Tat/Aat	0,17	0,92	0	probably_damaging	1	neutral	0,21	neutral	1,46	deleterious	-7,65	deleterious	-6,29	high_impact	5	neutral	0,86	damaging	0,13	deleterious	4,2	23,9	0,06	0,35	disease	0,86	disease	0,88	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,09	high_impact	3,35	0,12	0,8	56,84	8,69	P	0,64	P	0,99	polymorphism	1	0,26	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15563	15563	T	G	MI.10074	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	817	273	Y	D	Tat/Gat	0,17	0,92	0	probably_damaging	1	neutral	0,14	neutral	1,45	deleterious	-8,74	deleterious	-6,99	high_impact	5,34	neutral	0,83	damaging	0,1	deleterious	4,13	23,8	0,04	0,35	disease	0,9	disease	0,87	disease	0,81	disease	0,83	7	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,21	high_impact	3,66	0,09	0,8	56,84	8,69	P	0,61	P	1	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15564	15564	A	T	MI.10075	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	818	273	Y	F	tAt/tTt	5,67	1	0	probably_damaging	1	neutral	0,62	neutral	1,62	deleterious	-4,16	deleterious	-2,79	high_impact	5	neutral	0,87	damaging	0,11	deleterious	3,04	22,4	0,18	0,45	disease	0,69	disease	0,81	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,34	high_impact	3,35	0,4	0,8	56,84	8,69	P	0,73	P	0,83	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15564	15564	A	C	MI.10076	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	818	273	Y	S	tAt/tCt	5,67	1	0	probably_damaging	1	neutral	0,35	neutral	1,46	deleterious	-7,64	deleterious	-6,27	high_impact	5	neutral	0,85	damaging	0,11	deleterious	3,67	23,2	0,05	0,35	disease	0,73	disease	0,84	disease	0,77	disease	0,75	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,08	high_impact	3,35	0,15	0,8	56,84	8,69	P	0,72	P	1	polymorphism	1	0,26	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15564	15564	A	G	MI.10077	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	818	273	Y	C	tAt/tGt	5,67	1	0	probably_damaging	1	neutral	0,16	neutral	1,45	deleterious	-8,21	deleterious	-6,31	high_impact	5,34	neutral	0,91	damaging	0,07	deleterious	3,49	23,1	0,05	0,35	disease	0,89	disease	0,85	disease	0,78	disease	0,81	6	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,17	high_impact	3,66	0,08	0,8	56,84	8,69	P	0,7	P	1	polymorphism	1	0,26	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15566	15566	T	C	MI.10078	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	820	274	F	L	Ttc/Ctc	-3,27	0	0	benign	0,01	neutral	0,57	neutral	2,17	neutral	-2,86	deleterious	-4,18	medium_impact	3,42	neutral	0,97	damaging	0,12	deleterious	3,92	23,5	0,06	0,35	neutral	0,23	disease	0,81	disease	0,61	disease	0,67	3	neutral	0,41	deleterious	0,78	neutral	-3	neutral	0,22	medium_impact	1,13	medium_impact	0,29	medium_impact	1,91	0,43	0,8	58,42	8,71	N	0,25	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15566	15566	T	A	MI.10079	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	820	274	F	I	Ttc/Atc	-3,27	0	0	benign	0,25	neutral	0,43	neutral	1,99	deleterious	-4,74	deleterious	-4,18	high_impact	5,28	neutral	0,94	damaging	0,12	deleterious	4,48	24,2	0,06	0,35	neutral	0,34	disease	0,81	disease	0,67	disease	0,69	4	neutral	0,48	deleterious	0,59	neutral	-2	deleterious	0,52	medium_impact	-0,29	medium_impact	0,16	high_impact	3,6	0,38	0,8	58,42	8,71	P	0,6	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8999	8999	T	A	MI.1008	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	473	158	V	E	gTa/gAa	2,44	0,99	0	benign	0,17	deleterious	0	neutral	3,55	deleterious	-6,25	deleterious	-5,39	high_impact	4,29	neutral	0,8	neutral	0,54	deleterious	2,88	21,8	0,11	0,65	disease	0,96	disease	0,93	disease	0,72	disease	0,83	7	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,47	medium_impact	-0,1	low_impact	-1,4	high_impact	2,58	0,48	0,9	48,67	8,64	N	0,43	N	0,98	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15566	15566	T	G	MI.10080	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	820	274	F	V	Ttc/Gtc	-3,27	0	0	possibly_damaging	0,55	neutral	0,25	neutral	1,96	deleterious	-5,5	deleterious	-4,88	high_impact	5,28	neutral	0,95	damaging	0,11	deleterious	4,22	23,9	0,04	0,35	neutral	0,45	disease	0,86	disease	0,68	disease	0,73	5	neutral	0,74	neutral	0,35	deleterious	1	deleterious	0,58	medium_impact	-0,81	medium_impact	-0,04	high_impact	3,6	0,31	0,8	58,42	8,71	P	0,62	P	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15567	15567	T	A	MI.10081	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	821	274	F	Y	tTc/tAc	7,27	1	0	possibly_damaging	0,6	neutral	1	neutral	2,04	deleterious	-4	neutral	-2,09	medium_impact	3,49	neutral	0,95	damaging	0,11	deleterious	3,93	23,5	0,09	0,35	disease	0,71	disease	0,78	disease	0,59	disease	0,67	3	neutral	0,6	deleterious	0,7	NA	0	deleterious	0,71	medium_impact	-0,9	high_impact	1,85	medium_impact	1,98	0,44	0,8	58,42	8,71	N	0,48	N	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15567	15567	T	C	MI.10082	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	821	274	F	S	tTc/tCc	7,27	1	0	possibly_damaging	0,9	neutral	0,31	neutral	1,93	deleterious	-7,3	deleterious	-5,56	high_impact	4,93	neutral	0,93	damaging	0,08	deleterious	4,23	23,9	0,02	0,35	disease	0,68	disease	0,84	disease	0,67	disease	0,72	4	neutral	0,92	neutral	0,21	deleterious	1	deleterious	0,81	low_impact	-1,62	medium_impact	0,03	high_impact	3,28	0,22	0,8	58,42	8,71	P	0,66	P	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15567	15567	T	G	MI.10083	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	821	274	F	C	tTc/tGc	7,27	1	0	probably_damaging	0,98	neutral	0,09	neutral	1,92	deleterious	-8,37	deleterious	-5,6	high_impact	4,93	neutral	0,95	damaging	0,09	deleterious	4,18	23,8	0,03	0,35	disease	0,82	disease	0,83	disease	0,68	disease	0,73	5	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,82	low_impact	-2,31	medium_impact	-0,32	high_impact	3,28	0,23	0,8	58,42	8,71	P	0,63	P	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15568	15568	C	G	MI.10084	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	822	274	F	L	ttC/ttG	4,52	1	0	benign	0,01	neutral	0,57	neutral	2,17	neutral	-2,86	deleterious	-4,18	medium_impact	3,42	neutral	0,97	damaging	0,12	deleterious	4,12	23,8	0,06	0,35	neutral	0,23	disease	0,81	disease	0,61	disease	0,67	3	neutral	0,41	deleterious	0,78	neutral	-3	neutral	0,22	medium_impact	1,13	medium_impact	0,29	medium_impact	1,91	0,43	0,8	58,42	8,71	N	0,43	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15568	15568	C	A	MI.10085	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	822	274	F	L	ttC/ttA	4,52	1	0	benign	0,01	neutral	0,57	neutral	2,17	neutral	-2,86	deleterious	-4,18	medium_impact	3,42	neutral	0,97	damaging	0,12	deleterious	4,45	24,2	0,06	0,35	neutral	0,23	disease	0,81	disease	0,61	disease	0,67	3	neutral	0,41	deleterious	0,78	neutral	-3	neutral	0,22	medium_impact	1,13	medium_impact	0,29	medium_impact	1,91	0,43	0,8	58,42	8,71	N	0,43	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15569	15569	C	A	MI.10086	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	823	275	L	M	Cta/Ata	-1,44	0	0	probably_damaging	1	neutral	0,14	neutral	2,61	neutral	-2,92	neutral	-1,39	high_impact	4,43	neutral	0,86	damaging	0,07	deleterious	3,81	23,4	0,25	0,45	disease	0,72	disease	0,61	disease	0,55	disease	0,63	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	-0,21	high_impact	2,83	0,58	0,8	58,42	8,66	N	0,4	N	0,98	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15569	15569	C	G	MI.10087	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	823	275	L	V	Cta/Gta	-1,44	0	0	probably_damaging	0,99	neutral	0,34	neutral	2,66	neutral	-2,58	neutral	-2,07	high_impact	4,89	neutral	0,8	damaging	0,08	deleterious	3,28	22,8	0,19	0,45	disease	0,6	disease	0,71	disease	0,68	disease	0,67	3	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,81	low_impact	-2,59	medium_impact	0,07	high_impact	3,25	0,58	0,8	58,42	8,66	P	0,62	P	0,91	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15570	15570	T	A	MI.10088	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	824	275	L	Q	cTa/cAa	0,63	0,17	0	probably_damaging	1	neutral	0,23	neutral	2,6	deleterious	-4,79	deleterious	-4,17	high_impact	5,24	neutral	0,85	damaging	0,04	deleterious	4,21	23,9	0,03	0,35	disease	0,83	disease	0,82	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,06	high_impact	3,56	0,23	0,8	58,42	8,66	P	0,65	P	0,98	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15570	15570	T	C	MI.10089	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	824	275	L	P	cTa/cCa	0,63	0,17	0	probably_damaging	1	neutral	0,24	neutral	2,6	deleterious	-5,34	deleterious	-4,88	high_impact	4,68	neutral	0,86	damaging	0,03	deleterious	4,05	23,7	0,02	0,35	disease	0,89	disease	0,81	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,05	high_impact	3,06	0,24	0,8	58,42	8,66	N	0,58	P	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8999	8999	T	C	MI.1009	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	473	158	V	A	gTa/gCa	2,44	0,99	0	benign	0	neutral	0,05	neutral	3,58	deleterious	-4,13	deleterious	-3,54	high_impact	4,29	neutral	0,9	neutral	0,65	neutral	1,71	14,44	0,27	0,65	disease	0,86	disease	0,72	disease	0,6	disease	0,73	5	neutral	0,95	deleterious	0,53	neutral	-2	neutral	0,28	high_impact	2,09	medium_impact	-0,43	high_impact	2,58	0,45	0,9	48,67	8,64	P	0,51	P	0,6	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15570	15570	T	G	MI.10090	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	824	275	L	R	cTa/cGa	0,63	0,17	0	probably_damaging	1	neutral	0,32	neutral	2,61	deleterious	-4,44	deleterious	-4,17	high_impact	5,24	neutral	0,82	damaging	0,03	deleterious	4,32	24	0,02	0,35	disease	0,81	disease	0,89	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,05	high_impact	3,56	0,13	0,8	58,42	8,66	P	0,72	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15572	15572	T	A	MI.10091	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	826	276	F	I	Ttc/Atc	-0,06	0,91	0	probably_damaging	1	neutral	0,53	neutral	2,93	neutral	-1,62	deleterious	-4,16	high_impact	4,5	neutral	0,87	damaging	0,12	deleterious	4,28	24	0,08	0,35	disease	0,5	disease	0,85	disease	0,76	disease	0,75	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,25	high_impact	2,89	0,47	0,8	57,89	8,8	N	0,44	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15572	15572	T	C	MI.10092	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	826	276	F	L	Ttc/Ctc	-0,06	0,91	0	probably_damaging	0,99	neutral	0,98	neutral	2,98	neutral	-1,13	deleterious	-4,15	high_impact	3,9	neutral	0,92	damaging	0,1	deleterious	3,71	23,3	0,09	0,35	neutral	0,44	disease	0,84	disease	0,7	disease	0,74	5	deleterious	0,99	deleterious	0,5	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	1,14	high_impact	2,35	0,51	0,8	57,89	8,8	N	0,29	N	0,92	disease_causing_automatic	0	0,09	rs207459996	Pathogenic	Familial_colorectal_cancer	RCV000010315.4	MedGen	colorectal tumor	.	.	0,3	.	.	.	.	.	.
chrM	15572	15572	T	G	MI.10093	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	826	276	F	V	Ttc/Gtc	-0,06	0,91	0	probably_damaging	1	neutral	0,39	neutral	2,94	neutral	-1,22	deleterious	-4,85	high_impact	4,5	neutral	0,88	damaging	0,12	deleterious	4,08	23,7	0,05	0,35	neutral	0,45	disease	0,89	disease	0,77	disease	0,75	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,12	high_impact	2,89	0,31	0,8	57,89	8,8	N	0,52	P	0,99	polymorphism	1	0,11	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15573	15573	T	A	MI.10094	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	827	276	F	Y	tTc/tAc	7,27	1	0	probably_damaging	0,99	neutral	0,9	neutral	2,91	neutral	-2,63	neutral	-2,08	high_impact	4,24	neutral	0,88	damaging	0,12	deleterious	4,08	23,7	0,12	0,4	disease	0,57	disease	0,83	disease	0,72	disease	0,72	4	deleterious	0,99	neutral	0,46	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	0,74	high_impact	2,66	0,65	0,8	57,89	8,8	N	0,54	P	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15573	15573	T	G	MI.10095	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	827	276	F	C	tTc/tGc	7,27	1	0	probably_damaging	1	neutral	0,12	neutral	2,87	deleterious	-3,92	deleterious	-5,56	medium_impact	3,5	neutral	0,87	damaging	0,1	deleterious	4,23	23,9	0,03	0,35	disease	0,79	disease	0,86	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,84	low_impact	-3,53	medium_impact	-0,25	medium_impact	1,98	0,28	0,8	57,89	8,8	N	0,53	P	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15573	15573	T	C	MI.10096	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	827	276	F	S	tTc/tCc	7,27	1	0	probably_damaging	1	neutral	0,33	neutral	2,9	neutral	-2,17	deleterious	-5,52	high_impact	3,9	neutral	0,86	damaging	0,09	deleterious	4,35	24,1	0,02	0,35	disease	0,52	disease	0,87	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,06	high_impact	2,35	0,35	0,8	57,89	8,8	P	0,56	P	0,99	polymorphism	1	0,09	.	.	.	.	.	endometrial and ovarian tumors	.	.	.	.	.	.	.	.	.
chrM	15574	15574	C	A	MI.10097	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	828	276	F	L	ttC/ttA	5,67	1	0	probably_damaging	0,99	neutral	0,98	neutral	2,98	neutral	-1,13	deleterious	-4,15	high_impact	3,9	neutral	0,92	damaging	0,1	deleterious	4,36	24,1	0,09	0,35	neutral	0,44	disease	0,84	disease	0,7	disease	0,74	5	deleterious	0,99	deleterious	0,5	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	1,14	high_impact	2,35	0,51	0,8	57,89	8,8	N	0,49	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15574	15574	C	G	MI.10098	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	828	276	F	L	ttC/ttG	5,67	1	0	probably_damaging	0,99	neutral	0,98	neutral	2,98	neutral	-1,13	deleterious	-4,15	high_impact	3,9	neutral	0,92	damaging	0,1	deleterious	4,03	23,6	0,09	0,35	neutral	0,44	disease	0,84	disease	0,7	disease	0,74	5	deleterious	0,99	deleterious	0,5	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	1,14	high_impact	2,35	0,51	0,8	57,89	8,8	N	0,48	N	0,92	polymorphism	1	0,09	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15575	15575	G	T	MI.10099	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	829	277	A	S	Gcc/Tcc	-2,58	0	0	probably_damaging	1	neutral	0,4	neutral	2,86	neutral	-0,34	neutral	-2,07	medium_impact	2,93	neutral	0,87	damaging	0,09	deleterious	3,74	23,3	0,13	0,4	neutral	0,48	disease	0,85	neutral	0,48	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,83	low_impact	-3,53	medium_impact	0,13	medium_impact	1,47	0,45	0,8	55,79	8,53	N	0,24	N	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8572	8572	G	C	MI.101	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	46	16	G	R	Ggc/Cgc	0,13	0,8	0,01	possibly_damaging	0,9	deleterious	0,04	neutral	4,61	neutral	-0,54	deleterious	-6,33	high_impact	3,67	neutral	0,91	damaging	0,24	deleterious	3,55	23,1	0,22	0,65	disease	0,75	disease	0,93	disease	0,73	disease	0,81	6	deleterious	0,99	neutral	0,07	deleterious	5	deleterious	0,84	low_impact	-1,66	medium_impact	-0,49	high_impact	2,05	0,69	0,9	17,26	11,64	N	0,4	N	0,99	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9001	9001	C	A	MI.1010	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	475	159	R	S	Cgc/Agc	-9,59	0	0	probably_damaging	0,99	deleterious	0	neutral	0,96	deleterious	-11,35	deleterious	-5,25	high_impact	4,63	damaging	0,57	damaging	0,17	deleterious	4,66	24,5	0,15	0,65	disease	0,95	disease	0,88	disease	0,78	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,65	low_impact	-1,4	high_impact	2,87	0,28	0,9	49,12	8,85	N	0,43	N	0,77	disease_causing	0,95	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15575	15575	G	C	MI.10100	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	829	277	A	P	Gcc/Ccc	-2,58	0	0	probably_damaging	1	neutral	0,21	neutral	2,81	neutral	-2,81	deleterious	-3,49	high_impact	4,12	neutral	0,88	damaging	0,04	deleterious	3,88	23,5	0,02	0,35	disease	0,71	disease	0,88	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,09	high_impact	2,55	0,5	0,8	55,79	8,53	N	0,38	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15575	15575	G	A	MI.10101	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	829	277	A	T	Gcc/Acc	-2,58	0	0	probably_damaging	1	neutral	0,39	neutral	2,86	neutral	-0,51	deleterious	-2,76	high_impact	3,69	neutral	0,87	damaging	0,11	deleterious	4,3	24	0,06	0,35	neutral	0,45	disease	0,86	neutral	0,5	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,12	high_impact	2,16	0,7	0,85	55,79	8,53	N	0,31	N	0,79	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15576	15576	C	A	MI.10102	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	830	277	A	D	gCc/gAc	5,9	1	0	probably_damaging	1	neutral	0,2	neutral	2,8	deleterious	-3,34	deleterious	-4,17	high_impact	5,01	neutral	0,85	damaging	0,07	deleterious	4,64	24,5	0,02	0,35	disease	0,7	disease	0,92	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,1	high_impact	3,36	0,23	0,8	55,79	8,53	P	0,72	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15576	15576	C	T	MI.10103	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	830	277	A	V	gCc/gTc	5,9	1	0	probably_damaging	1	neutral	0,5	neutral	2,95	neutral	0,56	deleterious	-2,78	medium_impact	3,44	neutral	0,93	damaging	0,11	deleterious	4,55	24,4	0,04	0,35	neutral	0,26	disease	0,88	disease	0,52	disease	0,69	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,77	low_impact	-3,53	medium_impact	0,22	medium_impact	1,93	0,69	0,85	55,79	8,53	N	0,47	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15576	15576	C	G	MI.10104	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	830	277	A	G	gCc/gGc	5,9	1	0	probably_damaging	1	neutral	0,33	neutral	2,82	neutral	-2,29	deleterious	-2,78	high_impact	4,66	neutral	0,92	damaging	0,14	deleterious	3,86	23,5	0,11	0,4	neutral	0,4	disease	0,81	disease	0,58	disease	0,67	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,06	high_impact	3,04	0,64	0,8	55,79	8,53	P	0,58	P	0,83	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15578	15578	T	G	MI.10105	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	832	278	Y	D	Tac/Gac	-13,12	0	0	probably_damaging	1	neutral	0,2	neutral	1,74	deleterious	-7,57	deleterious	-6,88	high_impact	5,33	neutral	0,9	damaging	0,1	deleterious	4,06	23,7	0,01	0,35	disease	0,57	disease	0,91	disease	0,86	disease	0,8	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,1	high_impact	3,65	0,2	0,8	58,95	8,73	P	0,61	P	1	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15578	15578	T	A	MI.10106	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	832	278	Y	N	Tac/Aac	-13,12	0	0	probably_damaging	1	neutral	0,31	neutral	1,74	deleterious	-7,22	deleterious	-6,19	high_impact	5,33	neutral	0,92	damaging	0,13	deleterious	4,1	23,7	0,03	0,35	disease	0,62	disease	0,92	disease	0,81	disease	0,77	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,03	high_impact	3,65	0,18	0,8	58,95	8,73	P	0,64	P	0,99	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15578	15578	T	C	MI.10107	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	832	278	Y	H	Tac/Cac	-13,12	0	0	probably_damaging	1	neutral	0,53	neutral	1,77	deleterious	-5,9	deleterious	-3,44	high_impact	4,78	neutral	0,92	damaging	0,09	deleterious	3,66	23,2	0,09	0,35	disease	0,58	disease	0,85	disease	0,88	disease	0,77	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,25	high_impact	3,15	0,26	0,8	58,95	8,73	P	0,65	P	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15579	15579	A	C	MI.10108	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	833	278	Y	S	tAc/tCc	5,67	1	0	probably_damaging	1	neutral	0,4	neutral	1,74	deleterious	-7,28	deleterious	-6,17	high_impact	4,99	neutral	0,92	damaging	0,11	deleterious	3,82	23,4	0,03	0,35	disease	0,54	disease	0,9	disease	0,81	disease	0,77	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,13	high_impact	3,34	0,3	0,8	58,95	8,73	P	0,72	P	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15579	15579	A	T	MI.10109	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	833	278	Y	F	tAc/tTc	5,67	1	0	probably_damaging	1	neutral	0,7	neutral	1,96	deleterious	-3,27	deleterious	-2,75	high_impact	3,64	neutral	0,94	damaging	0,11	deleterious	3,27	22,8	0,15	0,4	neutral	0,48	disease	0,86	disease	0,8	disease	0,73	5	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,42	high_impact	2,11	0,42	0,8	58,95	8,73	P	0,57	P	0,83	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9001	9001	C	G	MI.1011	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	475	159	R	G	Cgc/Ggc	-9,59	0	0	probably_damaging	0,99	deleterious	0	neutral	0,96	deleterious	-11,14	deleterious	-6,2	high_impact	4,63	damaging	0,57	damaging	0,16	deleterious	4,3	24	0,16	0,65	disease	0,97	disease	0,84	disease	0,8	disease	0,85	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,65	low_impact	-1,4	high_impact	2,87	0,28	0,9	49,12	8,85	N	0,41	N	1	disease_causing	0,95	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15579	15579	A	G	MI.10110	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	833	278	Y	C	tAc/tGc	5,67	1	0	probably_damaging	1	neutral	0,17	neutral	1,73	deleterious	-7,98	deleterious	-6,21	high_impact	5,33	neutral	0,94	damaging	0,07	deleterious	3,69	23,3	0,02	0,35	disease	0,85	disease	0,9	disease	0,86	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,15	high_impact	3,65	0,15	0,8	58,95	8,73	P	0,78	P	1	disease_causing_automatic	0	0,26	rs207460002	Pathogenic	Multisystem_disorder	RCV000010321.2	MedGen	.	.	.	.	A15579G	Multisystem Disorder, EXIT	-	+	Confirmed	4
chrM	15581	15581	A	T	MI.10111	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	835	279	T	S	Aca/Tca	-0,52	0,38	0	benign	0,17	neutral	0,39	neutral	3,07	neutral	0,68	neutral	0,3	neutral_impact	0,01	neutral	0,84	neutral	0,63	deleterious	3,07	22,4	0,23	0,45	neutral	0,25	disease	0,55	neutral	0,48	neutral	0,48	0	neutral	0,53	deleterious	0,61	neutral	-6	neutral	0,2	medium_impact	-0,09	medium_impact	0,12	low_impact	-1,18	0,63	0,8	18,42	12,18	N	0,29	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15581	15581	A	C	MI.10112	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	835	279	T	P	Aca/Cca	-0,52	0,38	0	possibly_damaging	0,52	neutral	0,2	neutral	2,91	neutral	-2,19	neutral	-1,11	medium_impact	2,17	neutral	0,84	neutral	0,44	deleterious	3,49	23,1	0,04	0,35	neutral	0,5	disease	0,87	disease	0,55	disease	0,74	5	neutral	0,78	neutral	0,34	NA	0	neutral	0,42	medium_impact	-0,76	medium_impact	-0,1	medium_impact	0,78	0,31	0,8	18,42	12,18	N	0,29	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15581	15581	A	G	MI.10113	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	835	279	T	A	Aca/Gca	-0,52	0,38	0	benign	0,01	neutral	0,52	neutral	3,37	neutral	2,25	neutral	2,04	neutral_impact	-3,02	neutral	0,96	neutral	0,92	deleterious	0,43	6,85	0,17	0,45	neutral	0,26	neutral	0,07	neutral	0,19	neutral	0,25	5	neutral	0,47	deleterious	0,76	neutral	-6	neutral	0,11	medium_impact	1,13	medium_impact	0,24	low_impact	-3,94	0,24	0,8	18,42	12,18	N	0,37	N	0	polymorphism	1	0,01	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15582	15582	C	A	MI.10114	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	836	279	T	K	aCa/aAa	3,61	1	0	benign	0,25	neutral	0,29	neutral	2,96	neutral	-0,7	neutral	-1,09	medium_impact	2,17	neutral	0,84	neutral	0,55	deleterious	4,41	24,1	0,06	0,35	neutral	0,22	disease	0,78	disease	0,63	disease	0,72	4	neutral	0,65	deleterious	0,52	neutral	-3	neutral	0,27	medium_impact	-0,29	medium_impact	0,01	medium_impact	0,78	0,4	0,8	18,42	12,18	N	0,43	N	0,5	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15582	15582	C	T	MI.10115	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	836	279	T	M	aCa/aTa	3,61	1	0	possibly_damaging	0,85	neutral	0,21	neutral	2,91	neutral	-2,23	neutral	-1,09	medium_impact	2,17	neutral	0,85	neutral	0,51	deleterious	4,1	23,7	0,06	0,35	disease	0,56	disease	0,67	disease	0,54	disease	0,61	2	neutral	0,9	neutral	0,18	NA	0	deleterious	0,53	low_impact	-1,43	medium_impact	-0,09	medium_impact	0,78	0,49	0,8	18,42	12,18	N	0,44	N	0,61	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15584	15584	A	T	MI.10116	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	838	280	I	F	Att/Ttt	-8,31	0	0	probably_damaging	1	neutral	0,75	neutral	2,38	deleterious	-3,45	deleterious	-2,75	high_impact	4,54	neutral	0,88	damaging	0,1	deleterious	3,98	23,6	0,04	0,35	disease	0,66	disease	0,89	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,48	high_impact	2,93	0,59	0,8	57,11	8,78	N	0,36	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15584	15584	A	C	MI.10117	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	838	280	I	L	Att/Ctt	-8,31	0	0	probably_damaging	0,99	neutral	0,89	neutral	2,52	neutral	-1,95	neutral	-1,38	high_impact	3,79	neutral	0,89	damaging	0,09	deleterious	2,18	17,4	0,14	0,4	neutral	0,45	disease	0,82	disease	0,65	disease	0,69	4	deleterious	0,99	neutral	0,45	deleterious	2	deleterious	0,62	low_impact	-2,59	medium_impact	0,71	high_impact	2,25	0,58	0,8	57,11	8,78	N	0,21	N	0,88	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15584	15584	A	G	MI.10118	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	838	280	I	V	Att/Gtt	-8,31	0	0	probably_damaging	0,96	neutral	0,52	neutral	2,49	neutral	-2,19	neutral	-0,69	medium_impact	3,23	neutral	0,88	damaging	0,13	neutral	1,36	12,57	0,35	0,5	neutral	0,37	disease	0,65	disease	0,63	disease	0,66	3	neutral	0,96	neutral	0,28	deleterious	1	deleterious	0,68	low_impact	-2,02	medium_impact	0,24	medium_impact	1,74	0,51	0,8	57,11	8,78	N	0,25	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15585	15585	T	A	MI.10119	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	839	280	I	N	aTt/aAt	5,67	1	0	probably_damaging	1	neutral	0,34	neutral	2,32	deleterious	-5,94	deleterious	-4,82	high_impact	5,24	neutral	0,87	damaging	0,1	deleterious	4,67	24,5	0,05	0,35	disease	0,5	disease	0,93	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,07	high_impact	3,56	0,26	0,8	57,11	8,78	P	0,7	P	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9001	9001	C	T	MI.1012	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	475	159	R	C	Cgc/Tgc	-9,59	0	0	probably_damaging	1	deleterious	0	neutral	0,95	deleterious	-13,19	deleterious	-7,13	high_impact	4,63	damaging	0,52	damaging	0,11	deleterious	5,1	25,3	0,22	0,65	disease	0,99	disease	0,89	disease	0,82	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,62	0,9	49,12	8,85	N	0,39	N	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15585	15585	T	G	MI.10120	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	839	280	I	S	aTt/aGt	5,67	1	0	probably_damaging	1	neutral	0,42	neutral	2,33	deleterious	-4,82	deleterious	-4,11	high_impact	4,68	neutral	0,87	damaging	0,1	deleterious	4,44	24,2	0,01	0,35	disease	0,63	disease	0,92	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,15	high_impact	3,06	0,24	0,8	57,11	8,78	P	0,61	P	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15585	15585	T	C	MI.10121	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	839	280	I	T	aTt/aCt	5,67	1	0	probably_damaging	1	neutral	0,33	neutral	2,35	deleterious	-4,27	deleterious	-3,42	high_impact	3,99	neutral	0,87	damaging	0,09	deleterious	3,55	23,1	0,03	0,35	disease	0,59	disease	0,86	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,06	high_impact	2,43	0,28	0,8	57,11	8,78	N	0,5	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15586	15586	T	A	MI.10122	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	840	280	I	M	atT/atA	5,67	1	0,01	probably_damaging	1	neutral	0,18	neutral	2,43	neutral	-2,73	neutral	-2,06	medium_impact	3,11	neutral	0,88	damaging	0,09	deleterious	3,76	23,4	0,07	0,35	neutral	0,47	disease	0,79	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,75	low_impact	-3,53	medium_impact	-0,14	medium_impact	1,63	0,63	0,8	57,11	8,78	N	0,5	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15586	15586	T	G	MI.10123	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	840	280	I	M	atT/atG	5,67	1	0,01	probably_damaging	1	neutral	0,18	neutral	2,43	neutral	-2,73	neutral	-2,06	medium_impact	3,11	neutral	0,88	damaging	0,09	deleterious	3,45	23	0,07	0,35	neutral	0,47	disease	0,79	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,75	low_impact	-3,53	medium_impact	-0,14	medium_impact	1,63	0,63	0,8	57,11	8,78	N	0,48	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15587	15587	C	T	MI.10124	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	841	281	L	F	Ctc/Ttc	-2,35	0	0	probably_damaging	0,93	neutral	0,73	neutral	1,7	deleterious	-5,16	deleterious	-2,72	high_impact	4,38	neutral	0,95	damaging	0,09	deleterious	4,05	23,7	0,14	0,4	disease	0,57	disease	0,84	disease	0,52	disease	0,7	4	neutral	0,92	neutral	0,4	deleterious	2	deleterious	0,82	low_impact	-1,78	medium_impact	0,46	high_impact	2,78	0,5	0,8	56,84	8,52	N	0,3	N	0,97	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15587	15587	C	A	MI.10125	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	841	281	L	I	Ctc/Atc	-2,35	0	0	possibly_damaging	0,71	neutral	0,58	neutral	1,74	deleterious	-4,5	neutral	-1,36	high_impact	4,66	neutral	0,94	damaging	0,1	deleterious	4,03	23,7	0,22	0,45	neutral	0,43	disease	0,76	neutral	0,48	disease	0,57	1	neutral	0,67	neutral	0,44	deleterious	1	deleterious	0,67	low_impact	-1,09	medium_impact	0,3	high_impact	3,04	0,57	0,8	56,84	8,52	N	0,38	N	0,86	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15587	15587	C	G	MI.10126	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	841	281	L	V	Ctc/Gtc	-2,35	0	0	benign	0,36	neutral	0,52	neutral	1,7	deleterious	-5,17	neutral	-2,04	high_impact	5,35	neutral	0,96	damaging	0,16	deleterious	3,16	22,6	0,18	0,45	disease	0,63	disease	0,76	disease	0,61	disease	0,65	3	neutral	0,4	deleterious	0,58	neutral	-2	deleterious	0,54	medium_impact	-0,5	medium_impact	0,24	high_impact	3,66	0,37	0,8	56,84	8,52	N	0,55	P	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15588	15588	T	C	MI.10127	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	842	281	L	P	cTc/cCc	0,17	0,02	0	benign	0,08	neutral	0,24	neutral	1,63	deleterious	-8,36	deleterious	-4,81	high_impact	4,66	neutral	0,92	damaging	0,09	deleterious	3,97	23,6	0,02	0,35	disease	0,93	disease	0,87	disease	0,73	disease	0,76	5	neutral	0,73	deleterious	0,58	neutral	-2	neutral	0,43	medium_impact	0,26	medium_impact	-0,05	high_impact	3,04	0,25	0,8	56,84	8,52	N	0,51	P	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15588	15588	T	G	MI.10128	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	842	281	L	R	cTc/cGc	0,17	0,02	0	probably_damaging	0,93	neutral	0,41	neutral	1,63	deleterious	-8,44	deleterious	-4,11	high_impact	5,35	neutral	0,94	damaging	0,06	deleterious	4,19	23,9	0,02	0,35	disease	0,9	disease	0,92	disease	0,72	disease	0,75	5	neutral	0,93	neutral	0,24	deleterious	2	deleterious	0,9	low_impact	-1,78	medium_impact	0,14	high_impact	3,66	0,19	0,8	56,84	8,52	P	0,63	P	0,99	polymorphism	1	0,23	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15588	15588	T	A	MI.10129	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	842	281	L	H	cTc/cAc	0,17	0,02	0	probably_damaging	0,96	neutral	0,53	neutral	1,63	deleterious	-9,06	deleterious	-4,79	high_impact	5,35	neutral	0,93	damaging	0,08	deleterious	4,15	23,8	0,03	0,35	disease	0,92	disease	0,87	disease	0,7	disease	0,75	5	neutral	0,96	neutral	0,29	deleterious	2	deleterious	0,89	low_impact	-2,02	medium_impact	0,25	high_impact	3,66	0,26	0,8	56,84	8,52	P	0,62	P	0,95	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9002	9002	G	T	MI.1013	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	476	159	R	L	cGc/cTc	2,21	0,97	0	probably_damaging	0,99	deleterious	0	neutral	0,96	deleterious	-11,55	deleterious	-6,18	high_impact	4,63	damaging	0,56	damaging	0,13	deleterious	4,4	24,1	0,18	0,65	disease	0,97	disease	0,93	disease	0,79	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,65	low_impact	-1,4	high_impact	2,87	0,25	0,9	49,12	8,85	P	0,51	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15590	15590	C	T	MI.10130	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	844	282	R	W	Cga/Tga	-1,44	0	0	probably_damaging	1	neutral	0,18	neutral	2,09	deleterious	-8,11	deleterious	-5,51	high_impact	4,76	neutral	0,86	damaging	0,06	deleterious	5,21	25,5	0,07	0,35	disease	0,67	disease	0,94	disease	0,7	disease	0,8	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,14	high_impact	3,13	0,77	0,85	57,89	8,53	P	0,58	P	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15590	15590	C	G	MI.10131	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	844	282	R	G	Cga/Gga	-1,44	0	0	probably_damaging	1	neutral	0,41	neutral	2,12	deleterious	-5,38	deleterious	-4,81	high_impact	5,32	neutral	0,86	damaging	0,08	deleterious	3,95	23,6	0,06	0,35	disease	0,77	disease	0,88	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,14	high_impact	3,64	0,19	0,8	57,89	8,53	P	0,66	P	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15591	15591	G	A	MI.10132	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	845	282	R	Q	cGa/cAa	4,29	1	0	probably_damaging	0,99	neutral	0,28	neutral	2,17	deleterious	-3,96	deleterious	-2,75	high_impact	4,42	neutral	0,9	damaging	0,06	deleterious	3,03	22,3	0,14	0,4	disease	0,61	disease	0,9	disease	0,64	disease	0,7	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-2,59	medium_impact	0	high_impact	2,82	0,69	0,85	57,89	8,53	P	0,6	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15591	15591	G	C	MI.10133	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	845	282	R	P	cGa/cCa	4,29	1	0	probably_damaging	1	neutral	0,2	neutral	2,11	deleterious	-6,13	deleterious	-4,82	high_impact	4,97	neutral	0,86	damaging	0,04	deleterious	4,25	23,9	0,04	0,35	disease	0,82	disease	0,93	disease	0,82	disease	0,75	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,92	low_impact	-3,53	medium_impact	-0,1	high_impact	3,32	0,13	0,8	57,89	8,53	P	0,72	P	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15591	15591	G	T	MI.10134	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	845	282	R	L	cGa/cTa	4,29	1	0	probably_damaging	0,99	neutral	0,79	neutral	2,12	deleterious	-5,2	deleterious	-4,81	high_impact	4,51	neutral	0,87	damaging	0,06	deleterious	2,82	21,5	0,07	0,35	disease	0,67	disease	0,96	disease	0,68	disease	0,78	6	deleterious	0,99	neutral	0,4	deleterious	2	deleterious	0,9	low_impact	-2,59	medium_impact	0,53	high_impact	2,9	0,04	0,8	57,89	8,53	N	0,48	N	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15593	15593	T	A	MI.10135	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	847	283	S	T	Tcc/Acc	-3,04	0	0	probably_damaging	0,96	neutral	0,4	neutral	2,69	neutral	-2,09	neutral	-2,05	high_impact	3,52	neutral	0,83	neutral	0,42	deleterious	2,09	16,81	0,2	0,45	neutral	0,37	disease	0,79	neutral	0,47	disease	0,62	2	neutral	0,96	neutral	0,22	deleterious	2	deleterious	0,78	low_impact	-2,02	medium_impact	0,13	high_impact	2	0,49	0,8	58,42	8,63	N	0,28	N	0,7	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15593	15593	T	C	MI.10136	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	847	283	S	P	Tcc/Ccc	-3,04	0	0	probably_damaging	1	neutral	0,21	neutral	2,6	deleterious	-4,26	deleterious	-3,45	high_impact	4,21	neutral	0,78	neutral	0,33	deleterious	3,72	23,3	0,05	0,35	disease	0,82	disease	0,9	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,09	high_impact	2,63	0,13	0,8	58,42	8,63	N	0,49	N	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15593	15593	T	G	MI.10137	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	847	283	S	A	Tcc/Gcc	-3,04	0	0	probably_damaging	0,98	neutral	0,52	neutral	2,89	neutral	-0,47	neutral	-2,04	medium_impact	2,21	neutral	0,85	neutral	0,49	deleterious	2,07	16,66	0,23	0,45	neutral	0,4	disease	0,74	neutral	0,32	neutral	0,48	0	neutral	0,98	neutral	0,27	deleterious	1	deleterious	0,75	low_impact	-2,31	medium_impact	0,24	medium_impact	0,81	0,27	0,8	58,42	8,63	N	0,23	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15594	15594	C	A	MI.10138	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	848	283	S	Y	tCc/tAc	4,52	1	0	probably_damaging	1	neutral	1	neutral	2,6	deleterious	-4,55	deleterious	-4,12	high_impact	4,55	neutral	0,91	neutral	0,42	deleterious	4,19	23,9	0,05	0,35	disease	0,89	disease	0,93	disease	0,63	disease	0,73	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,9	low_impact	-3,53	high_impact	1,85	high_impact	2,94	0,17	0,8	58,42	8,63	N	0,49	N	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15594	15594	C	G	MI.10139	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	848	283	S	C	tCc/tGc	4,52	1	0	probably_damaging	1	neutral	0,18	neutral	2,64	deleterious	-3,02	deleterious	-3,45	high_impact	3,66	neutral	0,84	neutral	0,36	deleterious	3,57	23,2	0,06	0,35	disease	0,87	disease	0,88	disease	0,59	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,14	high_impact	2,13	0,27	0,8	58,42	8,63	N	0,48	N	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9002	9002	G	C	MI.1014	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	476	159	R	P	cGc/cCc	2,21	0,97	0	probably_damaging	1	deleterious	0	neutral	0,96	deleterious	-11,93	deleterious	-6,25	high_impact	4,63	damaging	0,44	damaging	0,14	deleterious	4,34	24	0,13	0,65	disease	0,98	disease	0,91	disease	0,87	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,26	0,9	49,12	8,85	P	0,58	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15594	15594	C	T	MI.10140	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	848	283	S	F	tCc/tTc	4,52	1	0	probably_damaging	1	neutral	0,7	neutral	2,6	deleterious	-4,24	deleterious	-4,12	high_impact	5,1	neutral	0,85	neutral	0,42	deleterious	4,19	23,8	0,05	0,35	disease	0,87	disease	0,93	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,42	high_impact	3,44	0,08	0,8	58,42	8,63	P	0,69	P	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15596	15596	G	T	MI.10141	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	850	284	V	F	Gtc/Ttc	-20	0	0	possibly_damaging	0,83	neutral	0,7	neutral	2,59	deleterious	-3,62	neutral	-2,2	low_impact	1,25	neutral	0,91	neutral	0,61	deleterious	3,83	23,4	0,04	0,35	disease	0,71	disease	0,88	neutral	0,48	disease	0,74	5	neutral	0,8	neutral	0,44	neutral	-3	deleterious	0,78	low_impact	-1,37	medium_impact	0,42	medium_impact	-0,06	0,43	0,8	21,32	38,15	N	0,23	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15596	15596	G	A	MI.10142	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	850	284	V	I	Gtc/Atc	-20	0	0	benign	0,05	neutral	0,67	neutral	3,21	neutral	0,68	neutral	0,52	neutral_impact	-2,01	neutral	0,89	neutral	0,91	neutral	-0,66	0,09	0,32	0,5	neutral	0,25	neutral	0,05	neutral	0,18	neutral	0,24	5	neutral	0,26	deleterious	0,81	neutral	-6	neutral	0,11	medium_impact	0,46	medium_impact	0,39	low_impact	-3,02	0,86	0,9	21,32	38,15	N	0,51	P	0,01	polymorphism	1	0	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15596	15596	G	C	MI.10143	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	850	284	V	L	Gtc/Ctc	-20	0	0	benign	0,28	neutral	0,8	neutral	2,69	neutral	-1,78	neutral	-0,84	low_impact	1,84	neutral	0,92	neutral	0,57	deleterious	2,07	16,65	0,14	0,4	neutral	0,34	disease	0,65	neutral	0,44	neutral	0,48	0	neutral	0,17	deleterious	0,76	neutral	-6	neutral	0,32	medium_impact	-0,35	medium_impact	0,55	medium_impact	0,48	0,55	0,8	21,32	38,15	N	0,24	N	0,2	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15597	15597	T	A	MI.10144	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	851	284	V	D	gTc/gAc	2,69	0,98	0	probably_damaging	0,95	neutral	0,23	neutral	2,56	deleterious	-5,96	deleterious	-4,17	medium_impact	3,13	neutral	0,86	neutral	0,49	deleterious	4,48	24,2	0,02	0,35	disease	0,92	disease	0,89	disease	0,72	disease	0,77	5	neutral	0,96	neutral	0,14	deleterious	1	deleterious	0,89	low_impact	-1,92	medium_impact	-0,06	medium_impact	1,65	0,31	0,8	21,32	38,15	N	0,47	N	0,49	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15597	15597	T	C	MI.10145	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	851	284	V	A	gTc/gCc	2,69	0,98	0	possibly_damaging	0,52	neutral	0,63	neutral	2,61	deleterious	-3,05	deleterious	-2,71	medium_impact	2,58	neutral	0,92	neutral	0,7	deleterious	2,12	16,99	0,09	0,4	disease	0,63	disease	0,54	disease	0,6	disease	0,66	3	neutral	0,45	deleterious	0,56	NA	0	deleterious	0,58	medium_impact	-0,76	medium_impact	0,35	medium_impact	1,15	0,38	0,8	21,32	38,15	N	0,41	N	0,34	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15597	15597	T	G	MI.10146	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	851	284	V	G	gTc/gGc	2,69	0,98	0	possibly_damaging	0,89	neutral	0,41	neutral	2,56	deleterious	-5,22	deleterious	-4,77	medium_impact	3,13	neutral	0,91	neutral	0,5	deleterious	3,72	23,3	0,02	0,35	disease	0,88	disease	0,77	disease	0,61	disease	0,77	5	neutral	0,89	neutral	0,26	NA	0	deleterious	0,83	low_impact	-1,58	medium_impact	0,14	medium_impact	1,65	0,26	0,8	21,32	38,15	N	0,53	P	0,53	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15599	15599	C	G	MI.10147	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	853	285	P	A	Cct/Gct	-4,64	0	0	benign	0,06	neutral	0,89	neutral	2,55	deleterious	-3,57	deleterious	-5,42	high_impact	4,47	neutral	0,87	damaging	0,11	neutral	1,51	13,37	0,19	0,45	disease	0,66	disease	0,81	disease	0,71	disease	0,71	4	neutral	0,03	deleterious	0,92	neutral	-2	neutral	0,36	medium_impact	0,38	medium_impact	0,71	high_impact	2,87	0,6	0,8	57,89	8,7	N	0,3	N	0,84	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15599	15599	C	T	MI.10148	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	853	285	P	S	Cct/Tct	-4,64	0	0	possibly_damaging	0,56	neutral	0,81	neutral	2,56	deleterious	-3,41	deleterious	-5,42	high_impact	4,24	neutral	0,84	damaging	0,07	deleterious	3,79	23,4	0,16	0,45	neutral	0,43	disease	0,91	disease	0,64	disease	0,71	4	neutral	0,48	deleterious	0,63	deleterious	1	deleterious	0,63	medium_impact	-0,83	medium_impact	0,56	high_impact	2,66	0,19	0,8	57,89	8,7	N	0,26	N	0,9	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15599	15599	C	A	MI.10149	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	853	285	P	T	Cct/Act	-4,64	0	0	benign	0,35	neutral	0,59	neutral	2,55	deleterious	-3,61	deleterious	-5,42	medium_impact	3,23	neutral	0,82	damaging	0,08	deleterious	3,56	23,1	0,17	0,45	disease	0,76	disease	0,88	disease	0,69	disease	0,71	4	neutral	0,34	deleterious	0,62	neutral	-3	deleterious	0,52	medium_impact	-0,48	medium_impact	0,31	medium_impact	1,74	0,49	0,8	57,89	8,7	N	0,2	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9002	9002	G	A	MI.1015	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	476	159	R	H	cGc/cAc	2,21	0,97	0	probably_damaging	1	deleterious	0	neutral	0,96	deleterious	-11,9	deleterious	-4,42	high_impact	4,63	damaging	0,54	damaging	0,11	deleterious	4,61	24,4	0,26	0,65	disease	0,97	disease	0,86	disease	0,82	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,64	0,9	49,12	8,85	P	0,52	P	1	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15600	15600	C	T	MI.10150	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	854	285	P	L	cCt/cTt	7,04	1	0	benign	0,02	neutral	0,59	neutral	2,52	deleterious	-4,29	deleterious	-6,79	high_impact	4,58	neutral	0,82	damaging	0,06	deleterious	4,37	24,1	0,09	0,35	disease	0,9	disease	0,93	disease	0,69	disease	0,67	3	neutral	0,38	deleterious	0,79	neutral	-2	neutral	0,37	medium_impact	0,85	medium_impact	0,31	high_impact	2,97	0,53	0,8	57,89	8,7	P	0,52	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15600	15600	C	A	MI.10151	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	854	285	P	H	cCt/cAt	7,04	1	0	probably_damaging	0,91	neutral	0,14	neutral	2,5	deleterious	-5,06	deleterious	-6,12	high_impact	5,28	neutral	0,84	damaging	0,07	deleterious	4,02	23,6	0,1	0,4	disease	0,94	disease	0,92	disease	0,71	disease	0,65	3	neutral	0,96	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-1,67	medium_impact	-0,21	high_impact	3,6	0,28	0,8	57,89	8,7	P	0,64	P	0,71	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15600	15600	C	G	MI.10152	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	854	285	P	R	cCt/cGt	7,04	1	0	possibly_damaging	0,88	neutral	0,55	neutral	2,52	deleterious	-4,22	deleterious	-6,12	high_impact	5,28	neutral	0,82	damaging	0,05	deleterious	3,66	23,2	0,08	0,35	disease	0,9	disease	0,94	disease	0,77	disease	0,69	4	neutral	0,86	neutral	0,34	deleterious	1	deleterious	0,86	low_impact	-1,54	medium_impact	0,27	high_impact	3,6	0,25	0,8	57,89	8,7	P	0,72	P	0,8	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15602	15602	A	G	MI.10153	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	856	286	N	D	Aac/Gac	-9,92	0	0	probably_damaging	0,97	neutral	0,23	neutral	2,92	neutral	-1,54	deleterious	-3,37	medium_impact	3,08	neutral	0,92	neutral	0,34	deleterious	2,21	17,56	0,43	0,55	neutral	0,37	disease	0,83	disease	0,61	disease	0,63	3	neutral	0,98	neutral	0,13	deleterious	1	deleterious	0,76	low_impact	-2,14	medium_impact	-0,06	medium_impact	1,6	0,28	0,8	57,11	8,52	N	0,39	N	0,96	polymorphism	1	0,04	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15602	15602	A	C	MI.10154	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	856	286	N	H	Aac/Cac	-9,92	0	0	probably_damaging	1	neutral	0,55	neutral	2,82	deleterious	-3,34	deleterious	-3,38	high_impact	4	neutral	0,94	damaging	0,19	deleterious	2,91	21,9	0,31	0,45	disease	0,74	disease	0,86	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,27	high_impact	2,44	0,12	0,8	57,11	8,52	N	0,27	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15602	15602	A	T	MI.10155	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	856	286	N	Y	Aac/Tac	-9,92	0	0	probably_damaging	1	neutral	1	neutral	2,81	deleterious	-3,75	deleterious	-5,41	high_impact	5,09	neutral	0,94	neutral	0,32	deleterious	3,73	23,3	0,07	0,35	disease	0,83	disease	0,91	disease	0,68	disease	0,73	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,88	low_impact	-3,53	high_impact	1,85	high_impact	3,43	0,11	0,8	57,11	8,52	P	0,61	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15603	15603	A	C	MI.10156	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	857	286	N	T	aAc/aCc	6,81	1	0	probably_damaging	0,98	neutral	0,41	neutral	2,86	neutral	-2,39	deleterious	-4,03	high_impact	3,94	neutral	0,95	neutral	0,4	deleterious	1,81	15,02	0,26	0,45	disease	0,61	disease	0,84	disease	0,64	disease	0,7	4	deleterious	0,98	neutral	0,22	deleterious	2	deleterious	0,83	low_impact	-2,31	medium_impact	0,14	high_impact	2,38	0,18	0,8	57,11	8,52	P	0,57	P	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15603	15603	A	G	MI.10157	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	857	286	N	S	aAc/aGc	6,81	1	0	probably_damaging	0,92	neutral	0,45	neutral	2,95	neutral	-1,27	deleterious	-3,35	low_impact	1,94	neutral	0,95	neutral	0,41	neutral	1,32	12,35	0,47	0,55	neutral	0,37	disease	0,84	disease	0,57	disease	0,63	3	neutral	0,92	neutral	0,27	neutral	-2	deleterious	0,77	low_impact	-1,72	medium_impact	0,18	medium_impact	0,57	0,13	0,8	57,11	8,52	N	0,49	N	0,91	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15603	15603	A	T	MI.10158	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	857	286	N	I	aAc/aTc	6,81	1	0	probably_damaging	1	neutral	0,44	neutral	2,79	deleterious	-4,84	deleterious	-6,08	high_impact	4,05	neutral	0,95	neutral	0,41	deleterious	3,84	23,4	0,07	0,35	disease	0,81	disease	0,91	disease	0,66	disease	0,73	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,17	high_impact	2,48	0,12	0,8	57,11	8,52	P	0,59	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15604	15604	C	A	MI.10159	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	858	286	N	K	aaC/aaA	6,81	1	0	probably_damaging	0,99	neutral	0,35	neutral	2,86	neutral	-2,45	deleterious	-4,05	high_impact	4,29	neutral	0,95	damaging	0,27	deleterious	4,16	23,8	0,29	0,45	neutral	0,31	disease	0,9	disease	0,62	disease	0,71	4	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,81	low_impact	-2,59	medium_impact	0,08	high_impact	2,7	0,35	0,8	57,11	8,52	N	0,55	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9004	9004	C	A	MI.1016	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	478	160	L	M	Cta/Ata	-3,34	0	0,01	possibly_damaging	0,55	deleterious	0,03	neutral	1,94	deleterious	-7,62	neutral	-1,8	high_impact	3,56	damaging	0,51	neutral	0,62	deleterious	3,44	23	0,25	0,65	disease	0,95	disease	0,67	disease	0,56	disease	0,79	6	neutral	0,97	neutral	0,24	deleterious	5	deleterious	0,63	medium_impact	-0,84	medium_impact	-0,56	medium_impact	1,95	0,63	0,9	50	8,83	N	0,38	N	0,96	disease_causing	0,9	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15604	15604	C	G	MI.10160	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	858	286	N	K	aaC/aaG	6,81	1	0	probably_damaging	0,99	neutral	0,35	neutral	2,86	neutral	-2,45	deleterious	-4,05	high_impact	4,29	neutral	0,95	damaging	0,27	deleterious	3,68	23,3	0,29	0,45	neutral	0,31	disease	0,9	disease	0,62	disease	0,71	4	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,81	low_impact	-2,59	medium_impact	0,08	high_impact	2,7	0,35	0,8	57,11	8,52	P	0,54	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15605	15605	A	C	MI.10161	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	859	287	K	Q	Aaa/Caa	-7,17	0	0	probably_damaging	0,98	neutral	0,29	neutral	2,19	deleterious	-3,71	deleterious	-2,71	high_impact	4,04	neutral	0,95	damaging	0,14	neutral	1,54	13,51	0,2	0,45	disease	0,68	disease	0,84	disease	0,76	disease	0,74	5	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,82	low_impact	-2,31	medium_impact	0,01	high_impact	2,48	0,28	0,8	58,16	8,7	N	0,42	N	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15605	15605	A	G	MI.10162	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	859	287	K	E	Aaa/Gaa	-7,17	0	0	probably_damaging	0,98	neutral	0,28	neutral	2,19	deleterious	-3,79	deleterious	-2,71	high_impact	3,83	neutral	0,8	damaging	0,13	deleterious	2,15	17,17	0,16	0,45	disease	0,65	disease	0,89	disease	0,8	disease	0,76	5	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-2,31	medium_impact	0	high_impact	2,28	0,31	0,8	58,16	8,7	N	0,39	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15606	15606	A	C	MI.10163	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	860	287	K	T	aAa/aCa	8,42	1	0	probably_damaging	1	neutral	0,39	neutral	2,15	deleterious	-4,73	deleterious	-4,05	high_impact	4,63	neutral	0,91	damaging	0,14	deleterious	3,48	23,1	0,07	0,35	disease	0,72	disease	0,83	disease	0,76	disease	0,74	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,12	high_impact	3,01	0,11	0,8	58,16	8,7	P	0,66	P	0,88	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15606	15606	A	T	MI.10164	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	860	287	K	M	aAa/aTa	8,42	1	0	probably_damaging	1	neutral	0,22	neutral	2,12	deleterious	-6,39	deleterious	-4,08	high_impact	4,63	neutral	0,91	damaging	0,15	deleterious	3,96	23,6	0,08	0,35	disease	0,88	disease	0,87	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,08	high_impact	3,01	0,19	0,8	58,16	8,7	P	0,68	P	0,67	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15607	15607	A	T	MI.10165	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	861	287	K	N	aaA/aaT	8,42	1	0,11	probably_damaging	1	neutral	0,32	neutral	2,16	deleterious	-4,44	deleterious	-3,38	high_impact	5,33	neutral	0,88	damaging	0,13	deleterious	3,71	23,3	0,3	0,45	disease	0,73	disease	0,84	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,05	high_impact	3,65	0,2	0,8	58,16	8,7	P	0,78	P	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15607	15607	A	C	MI.10166	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	861	287	K	N	aaA/aaC	8,42	1	0,11	probably_damaging	1	neutral	0,32	neutral	2,16	deleterious	-4,44	deleterious	-3,38	high_impact	5,33	neutral	0,88	damaging	0,13	deleterious	3,65	23,2	0,3	0,45	disease	0,73	disease	0,84	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,05	high_impact	3,65	0,2	0,8	58,16	8,7	P	0,78	P	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15608	15608	C	G	MI.10167	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	862	288	L	V	Cta/Gta	4,52	1	0	probably_damaging	0,98	neutral	0,33	neutral	2,8	neutral	-1,39	neutral	-1,97	high_impact	3,73	neutral	0,96	damaging	0,11	deleterious	1,83	15,15	0,2	0,45	neutral	0,33	disease	0,66	disease	0,68	disease	0,66	3	neutral	0,98	neutral	0,18	deleterious	2	deleterious	0,73	low_impact	-2,31	medium_impact	0,06	high_impact	2,19	0,45	0,8	58,16	8,77	N	0,47	N	0,91	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15608	15608	C	A	MI.10168	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	862	288	L	M	Cta/Ata	4,52	1	0	probably_damaging	1	neutral	0,13	neutral	2,7	neutral	-2,58	neutral	-1,34	high_impact	3,86	neutral	0,94	damaging	0,1	deleterious	3,9	23,5	0,2	0,45	disease	0,6	disease	0,66	disease	0,67	disease	0,65	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	-0,23	high_impact	2,31	0,52	0,8	58,16	8,77	N	0,49	N	0,98	polymorphism	1	0,03	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15609	15609	T	C	MI.10169	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	863	288	L	P	cTa/cCa	-0,06	0,94	0	probably_damaging	1	neutral	0,29	neutral	2,66	deleterious	-4,48	deleterious	-4,75	high_impact	5,18	neutral	0,94	damaging	0,05	deleterious	4,03	23,6	0,02	0,35	disease	0,77	disease	0,84	disease	0,83	disease	0,76	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,01	high_impact	3,51	0,24	0,8	58,16	8,77	P	0,71	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9004	9004	C	G	MI.1017	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	478	160	L	V	Cta/Gta	-3,34	0	0,01	benign	0,09	deleterious	0	neutral	1,95	deleterious	-7,25	deleterious	-2,69	high_impact	4,61	damaging	0,35	neutral	0,48	neutral	1,63	14,02	0,26	0,65	disease	0,95	disease	0,68	disease	0,69	disease	0,82	6	deleterious	1	neutral	0,46	deleterious	2	neutral	0,38	medium_impact	0,2	low_impact	-1,4	high_impact	2,85	0,61	0,9	50	8,83	P	0,56	P	0,87	disease_causing	0,92	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15609	15609	T	A	MI.10170	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	863	288	L	Q	cTa/cAa	-0,06	0,94	0	probably_damaging	1	neutral	0,59	neutral	2,68	deleterious	-3,9	deleterious	-4,08	high_impact	4,83	neutral	0,94	damaging	0,07	deleterious	4,43	24,2	0,02	0,35	disease	0,61	disease	0,85	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,31	high_impact	3,19	0,31	0,8	58,16	8,77	P	0,65	P	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15609	15609	T	G	MI.10171	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	863	288	L	R	cTa/cGa	-0,06	0,94	0	probably_damaging	1	neutral	0,54	neutral	2,68	deleterious	-4,06	deleterious	-4,08	high_impact	5,18	neutral	0,94	damaging	0,06	deleterious	4,27	23,9	0,02	0,35	disease	0,68	disease	0,88	disease	0,83	disease	0,78	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,26	high_impact	3,51	0,16	0,8	58,16	8,77	P	0,7	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15611	15611	G	T	MI.10172	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	865	289	G	W	Gga/Tga	-2,81	0	0	probably_damaging	1	neutral	0,19	neutral	2,87	deleterious	-3,35	deleterious	-5,47	medium_impact	3,25	neutral	0,86	damaging	0,05	deleterious	4,5	24,3	0,05	0,35	disease	0,53	disease	0,93	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,84	low_impact	-3,53	medium_impact	-0,12	medium_impact	1,76	0,06	0,8	57,63	8,73	N	0,31	N	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15611	15611	G	C	MI.10173	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	865	289	G	R	Gga/Cga	-2,81	0	0	probably_damaging	1	neutral	0,53	neutral	2,88	neutral	-2,93	deleterious	-5,46	high_impact	5,13	neutral	0,79	damaging	0,03	deleterious	3,98	23,6	0,05	0,35	neutral	0,49	disease	0,91	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,25	high_impact	3,46	0,56	0,8	57,63	8,73	P	0,62	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15612	15612	G	C	MI.10174	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	866	289	G	A	gGa/gCa	7,27	1	0	probably_damaging	1	neutral	0,78	neutral	2,94	neutral	-1,67	deleterious	-4,08	medium_impact	3,33	neutral	0,86	damaging	0,07	deleterious	3,15	22,6	0,08	0,35	neutral	0,3	disease	0,79	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,79	low_impact	-3,53	medium_impact	0,52	medium_impact	1,83	0,29	0,8	57,63	8,73	N	0,4	N	0,83	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15612	15612	G	A	MI.10175	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	866	289	G	E	gGa/gAa	7,27	1	0	probably_damaging	1	neutral	0,61	neutral	2,87	deleterious	-3,14	deleterious	-5,46	high_impact	4,78	neutral	0,72	damaging	0,04	deleterious	3,98	23,6	0,05	0,35	neutral	0,42	disease	0,92	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,33	high_impact	3,15	0,2	0,8	57,63	8,73	P	0,69	P	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15612	15612	G	T	MI.10176	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	866	289	G	V	gGa/gTa	7,27	1	0	probably_damaging	1	neutral	0,62	neutral	2,93	neutral	-1,93	deleterious	-6,14	high_impact	4,24	neutral	0,81	damaging	0,06	deleterious	3,86	23,5	0,04	0,35	neutral	0,36	disease	0,92	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,34	high_impact	2,66	0,16	0,8	57,63	8,73	N	0,46	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15614	15614	G	A	MI.10177	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	868	290	G	S	Ggc/Agc	-3,96	0	0	probably_damaging	1	neutral	0,41	neutral	1,42	deleterious	-5,52	deleterious	-4,12	high_impact	5,02	neutral	0,85	damaging	0,04	deleterious	4,25	23,9	0,05	0,35	disease	0,69	disease	0,86	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,14	high_impact	3,36	0,64	0,8	58,68	8,48	P	0,7	P	1	polymorphism	1	0,11	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15614	15614	G	C	MI.10178	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	868	290	G	R	Ggc/Cgc	-3,96	0	0	probably_damaging	1	neutral	0,35	neutral	1,36	deleterious	-8,3	deleterious	-5,5	high_impact	5,37	neutral	0,8	damaging	0,03	deleterious	4,07	23,7	0,02	0,35	disease	0,8	disease	0,9	disease	0,84	disease	0,76	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,08	high_impact	3,68	0,54	0,8	58,68	8,48	P	0,66	P	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15614	15614	G	T	MI.10179	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	868	290	G	C	Ggc/Tgc	-3,96	0	0	probably_damaging	1	neutral	0,18	neutral	1,35	deleterious	-8,73	deleterious	-6,19	high_impact	5,37	neutral	0,82	damaging	0,02	deleterious	4,3	24	0,03	0,35	disease	0,93	disease	0,9	disease	0,76	disease	0,67	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,14	high_impact	3,68	0,17	0,8	58,68	8,48	P	0,63	P	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9005	9005	T	G	MI.1018	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	479	160	L	R	cTa/cGa	-0,57	0	0	benign	0,17	deleterious	0	neutral	1,92	deleterious	-9,98	deleterious	-5,39	high_impact	4,61	damaging	0,29	neutral	0,39	deleterious	2,48	19,31	0,13	0,65	disease	0,99	disease	0,9	disease	0,78	disease	0,89	8	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,56	medium_impact	-0,1	low_impact	-1,4	high_impact	2,85	0,49	0,9	50	8,83	P	0,79	P	0,99	polymorphism	0,6	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15615	15615	G	A	MI.10180	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	869	290	G	D	gGc/gAc	9,11	1	0	probably_damaging	1	neutral	0,2	neutral	1,37	deleterious	-7,57	deleterious	-4,81	high_impact	5,37	neutral	0,8	damaging	0,04	deleterious	3,92	23,5	0,02	0,35	disease	0,7	disease	0,91	disease	0,84	disease	0,76	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,1	high_impact	3,68	0,17	0,8	58,68	8,48	P	0,82	P	1	disease_causing_automatic	0	0,23	rs207459997	Pathogenic	Exercise_intolerance	RCV000010316.4	MedGen	.	.	.	.	G15615A	EXIT/Antimycin resistance	-	+	Reported	3
chrM	15615	15615	G	C	MI.10181	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	869	290	G	A	gGc/gCc	9,11	1	0	probably_damaging	1	neutral	0,51	neutral	1,49	deleterious	-4,61	deleterious	-4,12	high_impact	5,37	neutral	0,87	damaging	0,07	deleterious	3,15	22,6	0,05	0,35	disease	0,68	disease	0,77	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,23	high_impact	3,68	0,42	0,8	58,68	8,48	P	0,74	P	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15615	15615	G	T	MI.10182	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	869	290	G	V	gGc/gTc	9,11	1	0	probably_damaging	1	neutral	0,52	neutral	1,36	deleterious	-7,97	deleterious	-6,19	high_impact	5,37	neutral	0,82	damaging	0,06	deleterious	3,85	23,4	0,02	0,35	disease	0,81	disease	0,9	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,24	high_impact	3,68	0,2	0,8	58,68	8,48	P	0,73	P	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15617	15617	G	A	MI.10183	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	871	291	V	I	Gtc/Atc	-10,6	0	0	probably_damaging	0,98	neutral	0,4	neutral	2,48	neutral	-1,94	neutral	-0,68	medium_impact	3,47	neutral	0,73	neutral	0,49	deleterious	1,89	15,5	0,43	0,55	neutral	0,49	disease	0,68	disease	0,62	disease	0,64	3	deleterious	0,98	neutral	0,21	deleterious	1	deleterious	0,76	low_impact	-2,31	medium_impact	0,13	medium_impact	1,96	0,83	0,9	57,37	8,75	N	0,3	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15617	15617	G	T	MI.10184	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	871	291	V	F	Gtc/Ttc	-10,6	0	0	probably_damaging	1	neutral	0,7	neutral	2,29	deleterious	-4,33	deleterious	-3,38	high_impact	3,54	neutral	0,81	neutral	0,44	deleterious	3,89	23,5	0,04	0,35	disease	0,51	disease	0,92	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,42	high_impact	2,02	0,26	0,8	57,37	8,75	N	0,21	N	0,98	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15617	15617	G	C	MI.10185	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	871	291	V	L	Gtc/Ctc	-10,6	0	0	probably_damaging	0,98	neutral	0,65	neutral	2,49	neutral	-1,85	neutral	-2,03	medium_impact	3,15	neutral	0,82	neutral	0,43	deleterious	1,88	15,46	0,18	0,45	neutral	0,31	disease	0,82	disease	0,66	disease	0,67	3	neutral	0,98	neutral	0,34	deleterious	1	deleterious	0,76	low_impact	-2,31	medium_impact	0,37	medium_impact	1,67	0,32	0,8	57,37	8,75	N	0,22	N	0,69	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15618	15618	T	C	MI.10186	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	872	291	V	A	gTc/gCc	5,9	1	0	probably_damaging	1	neutral	0,51	neutral	2,3	deleterious	-3,96	deleterious	-2,69	high_impact	4,04	neutral	0,73	neutral	0,52	deleterious	3,43	23	0,08	0,35	disease	0,6	disease	0,73	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,23	high_impact	2,48	0,16	0,8	57,37	8,75	P	0,62	P	0,62	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15618	15618	T	G	MI.10187	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	872	291	V	G	gTc/gGc	5,9	1	0	probably_damaging	1	neutral	0,34	neutral	2,25	deleterious	-6,12	deleterious	-4,71	high_impact	4,68	neutral	0,81	neutral	0,49	deleterious	3,85	23,4	0,03	0,35	disease	0,81	disease	0,84	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,07	high_impact	3,06	0,18	0,8	57,37	8,75	P	0,63	P	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15618	15618	T	A	MI.10188	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	872	291	V	D	gTc/gAc	5,9	1	0	probably_damaging	1	neutral	0,2	neutral	2,25	deleterious	-6,86	deleterious	-4,7	high_impact	4,68	neutral	0,76	neutral	0,42	deleterious	4,5	24,3	0,02	0,35	disease	0,89	disease	0,92	disease	0,78	disease	0,65	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,1	high_impact	3,06	0,15	0,8	57,37	8,75	P	0,68	P	0,98	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15620	15620	C	G	MI.10189	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	874	292	L	V	Ctt/Gtt	-11,06	0	0	benign	0,09	neutral	0,73	neutral	2,97	neutral	-0,14	neutral	-1,67	low_impact	1,6	neutral	0,96	neutral	0,82	deleterious	0,59	8,1	0,24	0,45	neutral	0,25	disease	0,52	neutral	0,37	neutral	0,42	2	neutral	0,16	deleterious	0,82	neutral	-6	neutral	0,22	medium_impact	0,21	medium_impact	0,46	medium_impact	0,26	0,55	0,8	25	12,47	N	0,25	N	0,17	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	9005	9005	T	A	MI.1019	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	479	160	L	Q	cTa/cAa	-0,57	0	0	benign	0,01	deleterious	0	neutral	1,91	deleterious	-10,14	deleterious	-5,39	high_impact	4,61	damaging	0,33	neutral	0,47	deleterious	2,24	17,77	0,16	0,65	disease	0,99	disease	0,86	disease	0,69	disease	0,84	7	deleterious	1	deleterious	0,5	deleterious	2	neutral	0,35	medium_impact	1,14	low_impact	-1,4	high_impact	2,85	0,54	0,9	50	8,83	P	0,58	P	0,98	polymorphism	0,65	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15620	15620	C	T	MI.10190	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	874	292	L	F	Ctt/Ttt	-11,06	0	0	possibly_damaging	0,44	neutral	0,28	neutral	2,73	neutral	-2,58	neutral	-2,49	medium_impact	3,34	neutral	0,95	damaging	0,13	deleterious	3,74	23,3	0,13	0,4	disease	0,71	disease	0,71	disease	0,62	disease	0,64	3	neutral	0,68	neutral	0,42	NA	0	deleterious	0,64	medium_impact	-0,63	medium_impact	0	medium_impact	1,84	0,42	0,8	25	12,47	N	0,3	N	0,64	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15620	15620	C	A	MI.10191	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	874	292	L	I	Ctt/Att	-11,06	0	0	benign	0,22	neutral	0,43	neutral	2,95	neutral	-0,24	neutral	-1,09	low_impact	1,48	neutral	0,96	neutral	0,72	neutral	1,51	13,35	0,22	0,45	neutral	0,28	neutral	0,46	neutral	0,29	neutral	0,42	2	neutral	0,48	deleterious	0,61	neutral	-6	neutral	0,25	medium_impact	-0,22	medium_impact	0,16	medium_impact	0,15	0,5	0,8	25	12,47	N	0,39	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	C15620A	Leigh Syndrome helper mut	-	+	Reported	1
chrM	15621	15621	T	A	MI.10192	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	875	292	L	H	cTt/cAt	-0,98	0	0	probably_damaging	0,91	neutral	0,15	neutral	2,68	deleterious	-4,45	deleterious	-4,43	high_impact	4,14	neutral	0,93	damaging	0,11	deleterious	4,11	23,7	0,03	0,35	disease	0,89	disease	0,83	disease	0,69	disease	0,77	5	neutral	0,95	neutral	0,12	deleterious	2	deleterious	0,83	low_impact	-1,67	medium_impact	-0,19	high_impact	2,57	0,26	0,8	25	12,47	N	0,42	N	0,86	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15621	15621	T	C	MI.10193	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	875	292	L	P	cTt/cCt	-0,98	0	0	probably_damaging	0,94	neutral	0,12	neutral	2,68	deleterious	-4,44	deleterious	-4,43	high_impact	4,14	neutral	0,94	damaging	0,08	deleterious	3,92	23,5	0,02	0,35	disease	0,88	disease	0,86	disease	0,73	disease	0,76	5	neutral	0,97	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-1,85	medium_impact	-0,25	high_impact	2,57	0,2	0,8	25	12,47	N	0,41	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15621	15621	T	G	MI.10194	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	875	292	L	R	cTt/cGt	-0,98	0	0	possibly_damaging	0,77	neutral	0,12	neutral	2,7	deleterious	-3,68	deleterious	-3,82	high_impact	4,84	neutral	0,94	damaging	0,08	deleterious	4,12	23,8	0,02	0,35	disease	0,85	disease	0,89	disease	0,73	disease	0,77	5	neutral	0,92	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-1,22	medium_impact	-0,25	high_impact	3,2	0,18	0,8	25	12,47	P	0,68	P	0,95	polymorphism	1	0,19	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15623	15623	G	C	MI.10195	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	877	293	A	P	Gcc/Ccc	-2,35	0	0	probably_damaging	1	neutral	0,11	neutral	2,78	deleterious	-3,94	deleterious	-3,38	high_impact	5,18	neutral	0,88	damaging	0,04	deleterious	3,84	23,4	0,03	0,35	disease	0,5	disease	0,9	disease	0,74	disease	0,75	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,27	high_impact	3,51	0,46	0,8	57,89	8,64	P	0,7	P	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15623	15623	G	A	MI.10196	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	877	293	A	T	Gcc/Acc	-2,35	0	0	probably_damaging	1	neutral	0,17	neutral	2,82	neutral	-2,73	deleterious	-2,7	high_impact	3,73	neutral	0,92	damaging	0,12	deleterious	4,17	23,8	0,11	0,4	disease	0,51	disease	0,82	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,15	high_impact	2,19	0,68	0,85	57,89	8,64	N	0,38	N	0,79	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15623	15623	G	T	MI.10197	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	877	293	A	S	Gcc/Tcc	-2,35	0	0	probably_damaging	1	neutral	0,26	neutral	2,81	neutral	-2,95	neutral	-2,02	high_impact	3,68	neutral	0,87	damaging	0,09	deleterious	3,61	23,2	0,18	0,45	disease	0,56	disease	0,85	disease	0,56	disease	0,67	3	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,02	high_impact	2,15	0,34	0,8	57,89	8,64	N	0,31	N	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15624	15624	C	G	MI.10198	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	878	293	A	G	gCc/gGc	5,9	1	0	probably_damaging	1	neutral	0,33	neutral	2,8	deleterious	-3,45	deleterious	-2,7	medium_impact	3,19	neutral	0,87	damaging	0,14	deleterious	3,73	23,3	0,16	0,45	disease	0,71	disease	0,79	disease	0,54	disease	0,66	3	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,78	low_impact	-3,53	medium_impact	0,06	medium_impact	1,7	0,7	0,85	57,89	8,64	N	0,5	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15624	15624	C	A	MI.10199	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	878	293	A	D	gCc/gAc	5,9	1	0	probably_damaging	1	neutral	0,08	neutral	2,77	deleterious	-4,44	deleterious	-4,05	high_impact	5,18	neutral	0,85	damaging	0,08	deleterious	4,57	24,4	0,03	0,35	disease	0,72	disease	0,93	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,35	high_impact	3,51	0,24	0,8	57,89	8,64	P	0,71	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8572	8572	G	T	MI.102	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	46	16	G	C	Ggc/Tgc	0,13	0,8	0,01	probably_damaging	0,96	deleterious	0,02	neutral	4,56	neutral	-2,75	deleterious	-7,26	high_impact	3,67	neutral	0,78	damaging	0,2	deleterious	3,82	23,4	0,2	0,65	disease	0,84	disease	0,9	disease	0,61	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,83	low_impact	-2,07	medium_impact	-0,66	high_impact	2,05	0,72	0,9	17,26	11,64	N	0,29	N	0,9	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9005	9005	T	C	MI.1020	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	479	160	L	P	cTa/cCa	-0,57	0	0	possibly_damaging	0,47	deleterious	0,03	neutral	1,91	deleterious	-10,36	deleterious	-6,33	high_impact	4,26	damaging	0,21	neutral	0,46	deleterious	2,33	18,36	0,15	0,65	disease	0,99	disease	0,85	disease	0,78	disease	0,88	8	neutral	0,97	neutral	0,28	deleterious	5	deleterious	0,67	medium_impact	-0,71	medium_impact	-0,56	high_impact	2,55	0,49	0,9	50	8,83	P	0,85	P	1	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15624	15624	C	T	MI.10200	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	878	293	A	V	gCc/gTc	5,9	1	0	probably_damaging	1	neutral	0,48	neutral	2,9	neutral	-1,59	deleterious	-2,7	medium_impact	3,22	neutral	0,88	damaging	0,11	deleterious	4,42	24,2	0,11	0,4	neutral	0,45	disease	0,87	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,8	low_impact	-3,53	medium_impact	0,2	medium_impact	1,73	0,68	0,85	57,89	8,64	N	0,5	N	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15626	15626	C	A	MI.10201	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	880	294	L	M	Cta/Ata	-3,5	0	0,01	probably_damaging	1	neutral	0,16	neutral	2,98	neutral	-0,06	neutral	-1,34	medium_impact	2,41	neutral	0,94	damaging	0,11	deleterious	3,75	23,3	0,17	0,45	neutral	0,33	disease	0,66	neutral	0,38	neutral	0,38	2	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,72	low_impact	-3,53	medium_impact	-0,17	medium_impact	1	0,43	0,8	58,16	8,69	N	0,33	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15626	15626	C	G	MI.10202	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	880	294	L	V	Cta/Gta	-3,5	0	0,01	probably_damaging	0,98	neutral	0,43	neutral	2,64	neutral	-2,32	neutral	-2,02	high_impact	4	neutral	0,96	damaging	0,12	deleterious	1,84	15,2	0,2	0,45	neutral	0,39	disease	0,67	disease	0,6	disease	0,65	3	neutral	0,98	neutral	0,23	deleterious	2	deleterious	0,74	low_impact	-2,31	medium_impact	0,16	high_impact	2,44	0,48	0,8	58,16	8,69	N	0,32	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15627	15627	T	A	MI.10203	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	881	294	L	Q	cTa/cAa	-0,06	0	0	probably_damaging	1	neutral	0,15	neutral	2,56	deleterious	-4,27	deleterious	-4,04	high_impact	4,05	neutral	0,93	damaging	0,08	deleterious	4,11	23,7	0,04	0,35	disease	0,8	disease	0,84	disease	0,6	disease	0,68	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,19	high_impact	2,48	0,22	0,8	58,16	8,69	N	0,39	N	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15627	15627	T	G	MI.10204	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	881	294	L	R	cTa/cGa	-0,06	0	0	probably_damaging	1	neutral	0,17	neutral	2,55	deleterious	-4,85	deleterious	-4,04	high_impact	4,75	neutral	0,94	damaging	0,06	deleterious	4,24	23,9	0,03	0,35	disease	0,79	disease	0,9	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,15	high_impact	3,12	0,18	0,8	58,16	8,69	P	0,69	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15627	15627	T	C	MI.10205	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	881	294	L	P	cTa/cCa	-0,06	0	0	probably_damaging	1	neutral	0,16	neutral	2,54	deleterious	-5,46	deleterious	-4,72	high_impact	4,2	neutral	0,93	damaging	0,06	deleterious	3,97	23,6	0,04	0,35	disease	0,82	disease	0,85	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,17	high_impact	2,62	0,21	0,8	58,16	8,69	N	0,42	N	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15629	15629	T	A	MI.10206	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	883	295	L	M	Tta/Ata	-1,21	0	0	benign	0,28	neutral	0,18	neutral	2,85	neutral	-1,87	neutral	-0,83	medium_impact	2,46	neutral	0,89	neutral	0,9	deleterious	2,54	19,72	0,26	0,45	neutral	0,45	disease	0,58	neutral	0,31	neutral	0,25	5	neutral	0,79	neutral	0,45	neutral	-3	neutral	0,29	medium_impact	-0,35	medium_impact	-0,14	medium_impact	1,04	0,49	0,8	21,32	27,73	N	0,44	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15629	15629	T	G	MI.10207	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	883	295	L	V	Tta/Gta	-1,21	0	0	possibly_damaging	0,52	neutral	0,4	neutral	3,02	neutral	0,15	neutral	-0,86	low_impact	0,81	neutral	0,95	neutral	0,95	neutral	0,98	10,56	0,27	0,45	neutral	0,19	neutral	0,33	neutral	0,24	neutral	0,45	1	neutral	0,59	neutral	0,44	neutral	-3	neutral	0,42	medium_impact	-0,76	medium_impact	0,13	medium_impact	-0,46	0,36	0,8	21,32	27,73	N	0,4	N	0,03	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15630	15630	T	G	MI.10208	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	884	295	L	W	tTa/tGa	-3,73	0	0	probably_damaging	0,98	deleterious	0,03	neutral	2,8	deleterious	-4,24	deleterious	-3,23	high_impact	4,38	neutral	0,84	neutral	0,47	deleterious	3,81	23,4	0,05	0,35	disease	0,8	disease	0,83	disease	0,58	disease	0,69	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,82	low_impact	-2,31	medium_impact	-0,6	high_impact	2,78	0,19	0,8	21,32	27,73	N	0,46	N	0,45	polymorphism	1	0,19	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15630	15630	T	C	MI.10209	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	884	295	L	S	tTa/tCa	-3,73	0	0	possibly_damaging	0,86	neutral	0,25	neutral	2,85	neutral	-1,85	deleterious	-2,77	medium_impact	3,23	neutral	0,83	neutral	0,62	deleterious	3,8	23,4	0,06	0,35	neutral	0,5	disease	0,76	disease	0,55	disease	0,65	3	neutral	0,89	neutral	0,2	NA	0	deleterious	0,73	low_impact	-1,47	medium_impact	-0,04	medium_impact	1,74	0,25	0,8	21,32	27,73	N	0,3	N	0,15	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9007	9007	A	T	MI.1021	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	481	161	T	S	Acc/Tcc	-6,81	0	0	probably_damaging	0,99	neutral	0,1	neutral	4,27	neutral	-0,63	deleterious	-3,59	medium_impact	2,08	damaging	0,6	neutral	0,64	deleterious	3,4	23	0,48	0,65	disease	0,67	disease	0,71	disease	0,52	disease	0,56	1	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,76	low_impact	-2,65	medium_impact	-0,25	medium_impact	0,69	0,78	0,9	50,44	8,87	N	0,31	N	0,88	disease_causing	0,52	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15631	15631	A	C	MI.10210	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	885	295	L	F	ttA/ttC	1,77	0,01	0	possibly_damaging	0,75	neutral	0,36	neutral	2,96	neutral	-0,34	neutral	-1,9	low_impact	1,66	neutral	0,85	neutral	0,83	deleterious	2,33	18,36	0,18	0,45	neutral	0,43	disease	0,68	neutral	0,31	neutral	0,25	5	neutral	0,78	neutral	0,31	neutral	-3	deleterious	0,69	low_impact	-1,18	medium_impact	0,09	medium_impact	0,31	0,41	0,8	21,32	27,73	N	0,34	N	0,03	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15631	15631	A	T	MI.10211	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	885	295	L	F	ttA/ttT	1,77	0,01	0	possibly_damaging	0,75	neutral	0,36	neutral	2,96	neutral	-0,34	neutral	-1,9	low_impact	1,66	neutral	0,85	neutral	0,83	deleterious	2,47	19,28	0,18	0,45	neutral	0,43	disease	0,68	neutral	0,31	neutral	0,25	5	neutral	0,78	neutral	0,31	neutral	-3	deleterious	0,69	low_impact	-1,18	medium_impact	0,09	medium_impact	0,31	0,41	0,8	21,32	27,73	N	0,34	N	0,03	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15632	15632	C	G	MI.10212	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	886	296	L	V	Cta/Gta	-7,62	0	0,01	possibly_damaging	0,52	neutral	0,69	neutral	2,89	neutral	-0,75	neutral	-0,73	medium_impact	3,01	neutral	0,95	neutral	0,58	deleterious	2,22	17,63	0,25	0,45	neutral	0,37	neutral	0,49	neutral	0,38	neutral	0,47	1	neutral	0,43	deleterious	0,59	NA	0	deleterious	0,51	medium_impact	-0,76	medium_impact	0,41	medium_impact	1,54	0,58	0,8	13,95	18,97	N	0,27	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15632	15632	C	A	MI.10213	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	886	296	L	M	Cta/Ata	-7,62	0	0,01	benign	0,28	neutral	0,26	neutral	2,84	neutral	-2,29	neutral	-0,16	neutral_impact	0,7	neutral	0,96	neutral	0,87	deleterious	2,34	18,45	0,22	0,45	neutral	0,41	neutral	0,25	neutral	0,26	neutral	0,46	1	neutral	0,69	deleterious	0,49	neutral	-6	neutral	0,3	medium_impact	-0,35	medium_impact	-0,02	medium_impact	-0,56	0,44	0,8	13,95	18,97	N	0,42	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15633	15633	T	G	MI.10214	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	887	296	L	R	cTa/cGa	-5,79	0	0	probably_damaging	0,93	neutral	0,19	neutral	2,78	deleterious	-3,4	neutral	-2,03	high_impact	4,11	neutral	0,94	neutral	0,45	deleterious	4,19	23,8	0,03	0,35	disease	0,62	disease	0,86	disease	0,55	disease	0,67	3	neutral	0,96	neutral	0,13	deleterious	2	deleterious	0,82	low_impact	-1,78	medium_impact	-0,12	high_impact	2,54	0,22	0,8	13,95	18,97	N	0,45	N	0,9	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15633	15633	T	A	MI.10215	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	887	296	L	Q	cTa/cAa	-5,79	0	0	probably_damaging	0,93	neutral	0,16	neutral	2,78	deleterious	-3,54	neutral	-1,93	high_impact	4,11	neutral	0,94	neutral	0,5	deleterious	4,27	24	0,04	0,35	disease	0,62	disease	0,63	neutral	0,41	neutral	0,44	1	neutral	0,96	neutral	0,12	deleterious	2	deleterious	0,75	low_impact	-1,78	medium_impact	-0,17	high_impact	2,54	0,24	0,8	13,95	18,97	N	0,48	N	0,82	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15633	15633	T	C	MI.10216	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	887	296	L	P	cTa/cCa	-5,79	0	0	probably_damaging	0,96	neutral	0,25	neutral	2,77	deleterious	-3,68	deleterious	-2,52	medium_impact	3,31	neutral	0,93	neutral	0,34	deleterious	4,01	23,6	0,03	0,35	disease	0,56	disease	0,87	disease	0,55	disease	0,68	4	neutral	0,97	neutral	0,15	deleterious	1	deleterious	0,82	low_impact	-2,02	medium_impact	-0,04	medium_impact	1,81	0,16	0,8	13,95	18,97	N	0,37	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15635	15635	T	C	MI.10217	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	889	297	S	P	Tcc/Ccc	-4,64	0	0	probably_damaging	1	neutral	0,26	neutral	2,66	deleterious	-4,03	deleterious	-3,32	high_impact	5,18	neutral	0,93	neutral	0,33	deleterious	3,8	23,4	0,04	0,35	disease	0,76	disease	0,87	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,02	high_impact	3,51	0,25	0,8	57,63	8,46	P	0,77	P	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	T15635C	Polyvisceral failure	+	-	Reported	1
chrM	15635	15635	T	A	MI.10218	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	889	297	S	T	Tcc/Acc	-4,64	0	0	probably_damaging	0,98	neutral	0,32	neutral	2,72	neutral	-2,23	neutral	-1,98	high_impact	4,08	neutral	0,95	neutral	0,42	deleterious	2,1	16,86	0,23	0,45	disease	0,51	disease	0,67	disease	0,64	disease	0,65	3	deleterious	0,98	neutral	0,17	deleterious	2	deleterious	0,77	low_impact	-2,31	medium_impact	0,05	high_impact	2,51	0,5	0,8	57,63	8,46	N	0,4	N	0,7	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15635	15635	T	G	MI.10219	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	889	297	S	A	Tcc/Gcc	-4,64	0	0	probably_damaging	0,99	neutral	0,7	neutral	2,92	neutral	-0,38	neutral	-1,96	medium_impact	2,38	neutral	0,96	neutral	0,49	deleterious	2,09	16,79	0,24	0,45	neutral	0,24	disease	0,61	neutral	0,47	neutral	0,17	7	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,71	low_impact	-2,59	medium_impact	0,42	medium_impact	0,97	0,37	0,8	57,63	8,46	N	0,24	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9007	9007	A	G	MI.1022	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	481	161	T	A	Acc/Gcc	-6,81	0	0	probably_damaging	0,99	neutral	0,47	neutral	4,32	neutral	0,4	deleterious	-4,49	low_impact	1,17	neutral	0,73	neutral	0,61	deleterious	3,58	23,2	0,58	0,7	neutral	0,38	neutral	0,39	neutral	0,38	neutral	0,4	2	deleterious	0,99	neutral	0,24	neutral	-2	deleterious	0,69	low_impact	-2,65	medium_impact	0,26	medium_impact	-0,1	0,44	0,9	50,44	8,87	N	0,32	N	0,63	disease_causing	0,77	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15636	15636	C	T	MI.10220	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	890	297	S	F	tCc/tTc	5,44	1	0	probably_damaging	1	neutral	0,73	neutral	2,67	deleterious	-3,79	deleterious	-3,98	high_impact	4,21	neutral	0,95	neutral	0,51	deleterious	4,21	23,9	0,05	0,35	disease	0,61	disease	0,9	disease	0,61	disease	0,67	3	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,46	high_impact	2,63	0,08	0,8	57,63	8,46	N	0,49	N	1	polymorphism	1	0,05	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15636	15636	C	G	MI.10221	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	890	297	S	C	tCc/tGc	5,44	1	0	probably_damaging	1	neutral	0,12	neutral	2,65	deleterious	-4,67	deleterious	-3,31	high_impact	4,84	neutral	0,95	neutral	0,36	deleterious	3,58	23,2	0,08	0,35	disease	0,76	disease	0,79	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	-0,25	high_impact	3,2	0,23	0,8	57,63	8,46	P	0,71	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15636	15636	C	A	MI.10222	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	890	297	S	Y	tCc/tAc	5,44	1	0	probably_damaging	1	neutral	0,81	neutral	2,66	deleterious	-4,06	deleterious	-3,98	high_impact	4,63	neutral	0,95	neutral	0,39	deleterious	4,22	23,9	0,06	0,35	disease	0,68	disease	0,88	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,41	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,56	high_impact	3,01	0,2	0,8	57,63	8,46	P	0,55	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15638	15638	A	T	MI.10223	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	892	298	I	F	Atc/Ttc	-20	0	0	probably_damaging	1	neutral	0,69	neutral	2,53	deleterious	-3,1	deleterious	-2,66	high_impact	3,67	neutral	0,77	neutral	0,37	deleterious	3,78	23,4	0,11	0,4	neutral	0,41	disease	0,8	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,41	high_impact	2,14	0,48	0,8	56,05	8,69	N	0,23	N	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15638	15638	A	C	MI.10224	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	892	298	I	L	Atc/Ctc	-20	0	0	probably_damaging	0,99	neutral	1	neutral	2,77	neutral	-0,91	neutral	-1,32	medium_impact	2,73	neutral	0,84	neutral	0,35	deleterious	2,18	17,38	0,26	0,45	neutral	0,31	disease	0,73	neutral	0,43	neutral	0,47	1	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,68	low_impact	-2,59	high_impact	1,85	medium_impact	1,29	0,5	0,8	56,05	8,69	N	0,17	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15638	15638	A	G	MI.10225	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	892	298	I	V	Atc/Gtc	-20	0	0	probably_damaging	0,96	neutral	0,54	neutral	2,71	neutral	-1,25	neutral	-0,54	low_impact	1,63	neutral	0,92	neutral	0,46	neutral	1,28	12,16	0,44	0,55	neutral	0,35	neutral	0,37	neutral	0,45	neutral	0,4	2	neutral	0,96	neutral	0,29	neutral	-2	deleterious	0,65	low_impact	-2,02	medium_impact	0,26	medium_impact	0,29	0,49	0,8	56,05	8,69	N	0,31	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15639	15639	T	A	MI.10226	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	893	298	I	N	aTc/aAc	5,44	1	0	probably_damaging	1	neutral	0,19	neutral	2,47	deleterious	-5,35	deleterious	-4,59	high_impact	4,05	neutral	0,86	neutral	0,39	deleterious	4,5	24,3	0,08	0,35	disease	0,76	disease	0,81	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,12	high_impact	2,48	0,34	0,8	56,05	8,69	P	0,57	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15639	15639	T	C	MI.10227	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	893	298	I	T	aTc/aCc	5,44	1	0	probably_damaging	1	neutral	0,26	neutral	2,51	deleterious	-3,68	deleterious	-3,19	high_impact	4,54	neutral	0,86	neutral	0,41	deleterious	3,39	23	0,08	0,35	disease	0,56	disease	0,68	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	-0,02	high_impact	2,93	0,26	0,8	56,05	8,69	P	0,59	P	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15639	15639	T	G	MI.10228	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	893	298	I	S	aTc/aGc	5,44	1	0	probably_damaging	1	neutral	0,83	neutral	2,49	deleterious	-4,22	deleterious	-3,92	high_impact	4,54	neutral	0,84	neutral	0,39	deleterious	4,32	24	0,04	0,35	disease	0,61	disease	0,83	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,6	high_impact	2,93	0,25	0,8	56,05	8,69	N	0,51	P	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15640	15640	C	A	MI.10229	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	894	298	I	M	atC/atA	5,67	1	0	probably_damaging	1	neutral	0,33	neutral	2,51	deleterious	-3,6	neutral	-1,92	high_impact	4,05	neutral	0,84	neutral	0,36	deleterious	3,86	23,5	0,16	0,45	disease	0,61	disease	0,71	disease	0,59	disease	0,64	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,06	high_impact	2,48	0,46	0,8	56,05	8,69	P	0,56	P	0,83	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9007	9007	A	C	MI.1023	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	481	161	T	P	Acc/Ccc	-6,81	0	0	probably_damaging	1	deleterious	0,01	neutral	4,21	neutral	-2,78	deleterious	-5,47	high_impact	3,93	damaging	0,52	neutral	0,48	deleterious	3,57	23,2	0,18	0,65	disease	0,84	disease	0,88	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,6	medium_impact	-0,84	high_impact	2,27	0,54	0,9	50,44	8,87	N	0,36	N	0,99	disease_causing	0,94	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15640	15640	C	G	MI.10230	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	894	298	I	M	atC/atG	5,67	1	0	probably_damaging	1	neutral	0,33	neutral	2,51	deleterious	-3,6	neutral	-1,92	high_impact	4,05	neutral	0,84	neutral	0,36	deleterious	3,38	22,9	0,16	0,45	disease	0,61	disease	0,71	disease	0,59	disease	0,64	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,06	high_impact	2,48	0,46	0,8	56,05	8,69	P	0,55	P	0,83	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15641	15641	C	G	MI.10231	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	895	299	L	V	Ctc/Gtc	-2,58	0	0	probably_damaging	0,98	neutral	0,53	neutral	2,86	neutral	-0,28	neutral	-1,61	low_impact	1,85	neutral	0,97	neutral	0,65	deleterious	1,84	15,2	0,32	0,5	neutral	0,31	disease	0,61	neutral	0,36	neutral	0,37	3	neutral	0,97	neutral	0,28	neutral	-2	deleterious	0,72	low_impact	-2,31	medium_impact	0,25	medium_impact	0,49	0,49	0,8	41,05	8,01	N	0,24	N	0,91	polymorphism	1	0,03	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15641	15641	C	A	MI.10232	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	895	299	L	I	Ctc/Atc	-2,58	0	0	probably_damaging	0,99	neutral	0,98	neutral	2,81	neutral	-0,79	neutral	-1,11	medium_impact	2,52	neutral	0,94	neutral	0,49	deleterious	3,84	23,4	0,32	0,5	neutral	0,34	disease	0,66	neutral	0,47	neutral	0,37	3	deleterious	0,99	deleterious	0,5	deleterious	1	deleterious	0,73	low_impact	-2,59	medium_impact	1,14	medium_impact	1,1	0,39	0,8	41,05	8,01	N	0,21	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15641	15641	C	T	MI.10233	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	895	299	L	F	Ctc/Ttc	-2,58	0	0	probably_damaging	1	neutral	0,59	neutral	2,78	neutral	-2,69	neutral	-2,29	medium_impact	2,52	neutral	0,96	neutral	0,52	deleterious	3,91	23,5	0,21	0,45	disease	0,57	disease	0,65	neutral	0,4	neutral	0,23	5	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,79	low_impact	-3,53	medium_impact	0,31	medium_impact	1,1	0,35	0,8	41,05	8,01	N	0,2	N	0,97	polymorphism	1	0,03	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15642	15642	T	A	MI.10234	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	896	299	L	H	cTc/cAc	-0,06	0	0	probably_damaging	1	neutral	0,12	neutral	2,7	deleterious	-4,21	deleterious	-4,08	high_impact	4,82	neutral	0,93	neutral	0,42	deleterious	4,19	23,8	0,05	0,35	disease	0,76	disease	0,81	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,25	high_impact	3,18	0,16	0,8	41,05	8,01	P	0,69	P	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15642	15642	T	G	MI.10235	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	896	299	L	R	cTc/cGc	-0,06	0	0	probably_damaging	1	neutral	0,05	neutral	2,72	deleterious	-3,52	deleterious	-3,45	high_impact	4,82	neutral	0,94	neutral	0,41	deleterious	4,24	23,9	0,02	0,35	disease	0,7	disease	0,89	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,47	high_impact	3,18	0,16	0,8	41,05	8,01	P	0,72	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15642	15642	T	C	MI.10236	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	896	299	L	P	cTc/cCc	-0,06	0	0	probably_damaging	1	neutral	0,11	neutral	2,7	deleterious	-3,76	deleterious	-4,05	high_impact	4,12	neutral	0,97	neutral	0,37	deleterious	3,97	23,6	0,03	0,35	disease	0,77	disease	0,83	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,27	high_impact	2,55	0,2	0,8	41,05	8,01	N	0,46	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15644	15644	A	G	MI.10237	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	898	300	I	V	Atc/Gtc	-1,21	0	0	probably_damaging	0,96	neutral	0,53	neutral	2,99	neutral	-0,26	neutral	-0,14	neutral_impact	0,56	neutral	0,94	neutral	0,97	neutral	-0,49	0,24	0,38	0,5	neutral	0,27	neutral	0,08	neutral	0,39	neutral	0,29	4	neutral	0,96	neutral	0,29	neutral	-2	deleterious	0,6	low_impact	-2,02	medium_impact	0,25	medium_impact	-0,69	0,34	0,8	59,21	9,43	N	0,39	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15644	15644	A	T	MI.10238	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	898	300	I	F	Atc/Ttc	-1,21	0	0	probably_damaging	1	neutral	0,56	neutral	2,8	neutral	-2,33	deleterious	-2,61	medium_impact	3,44	neutral	0,77	neutral	0,44	deleterious	3,7	23,3	0,13	0,4	disease	0,54	disease	0,75	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,78	low_impact	-3,53	medium_impact	0,28	medium_impact	1,93	0,38	0,8	59,21	9,43	N	0,22	N	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15644	15644	A	C	MI.10239	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	898	300	I	L	Atc/Ctc	-1,21	0	0	probably_damaging	0,99	neutral	1	neutral	2,92	neutral	-0,9	neutral	-1,3	medium_impact	2,92	neutral	0,84	neutral	0,44	deleterious	2,18	17,35	0,24	0,45	neutral	0,26	disease	0,67	disease	0,52	disease	0,56	1	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,53	low_impact	-2,59	high_impact	1,85	medium_impact	1,46	0,34	0,8	59,21	9,43	N	0,19	N	0,88	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9008	9008	C	A	MI.1024	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	482	161	T	N	aCc/aAc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	4,22	neutral	-2,32	deleterious	-4,53	high_impact	3,93	neutral	0,62	neutral	0,53	deleterious	3,8	23,4	0,42	0,65	disease	0,81	disease	0,84	disease	0,64	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,6	low_impact	-1,4	high_impact	2,27	0,76	0,9	50,44	8,87	P	0,5	N	0,9	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15645	15645	T	C	MI.10240	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	899	300	I	T	aTc/aCc	-0,29	0	0	probably_damaging	1	neutral	0,18	neutral	2,81	neutral	-2,38	deleterious	-2,74	high_impact	4	neutral	0,85	neutral	0,52	deleterious	3,51	23,1	0,07	0,35	neutral	0,48	disease	0,57	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,73	low_impact	-3,53	medium_impact	-0,14	high_impact	2,44	0,19	0,8	59,21	9,43	N	0,41	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15645	15645	T	G	MI.10241	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	899	300	I	S	aTc/aGc	-0,29	0	0	probably_damaging	1	neutral	0,33	neutral	2,8	neutral	-2,59	deleterious	-3,64	medium_impact	3,42	neutral	0,84	neutral	0,43	deleterious	4,4	24,1	0,03	0,35	neutral	0,38	disease	0,77	disease	0,6	disease	0,66	3	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,73	low_impact	-3,53	medium_impact	0,06	medium_impact	1,91	0,25	0,8	59,21	9,43	N	0,3	N	0,98	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15645	15645	T	A	MI.10242	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	899	300	I	N	aTc/aAc	-0,29	0	0	probably_damaging	1	neutral	0,21	neutral	2,75	deleterious	-4,06	deleterious	-4,32	high_impact	4,25	neutral	0,83	neutral	0,45	deleterious	4,56	24,4	0,06	0,35	disease	0,68	disease	0,75	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	-0,09	high_impact	2,67	0,27	0,8	59,21	9,43	N	0,41	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15646	15646	C	A	MI.10243	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	900	300	I	M	atC/atA	2,92	0,28	0	probably_damaging	1	neutral	0,4	neutral	2,8	neutral	-2,61	neutral	-1,7	medium_impact	3,28	neutral	0,84	neutral	0,35	deleterious	3,84	23,4	0,17	0,45	disease	0,54	disease	0,6	disease	0,54	disease	0,5	0	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-3,53	medium_impact	0,13	medium_impact	1,79	0,43	0,8	59,21	9,43	N	0,3	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15646	15646	C	G	MI.10244	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	900	300	I	M	atC/atG	2,92	0,28	0	probably_damaging	1	neutral	0,4	neutral	2,8	neutral	-2,61	neutral	-1,7	medium_impact	3,28	neutral	0,84	neutral	0,35	deleterious	3,37	22,9	0,17	0,45	disease	0,54	disease	0,6	disease	0,54	disease	0,5	0	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-3,53	medium_impact	0,13	medium_impact	1,79	0,43	0,8	59,21	9,43	N	0,3	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15647	15647	C	A	MI.10245	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	901	301	L	M	Cta/Ata	-6,02	0	0	probably_damaging	1	neutral	0,26	neutral	2,45	neutral	-2,86	neutral	-1,31	high_impact	4,22	neutral	0,87	damaging	0,1	deleterious	3,77	23,4	0,17	0,45	neutral	0,49	disease	0,54	disease	0,54	disease	0,61	2	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,72	low_impact	-3,53	medium_impact	-0,02	high_impact	2,64	0,52	0,8	59,47	8,53	N	0,38	N	0,98	polymorphism	1	0,03	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15647	15647	C	G	MI.10246	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	901	301	L	V	Cta/Gta	-6,02	0	0	probably_damaging	0,99	neutral	0,55	neutral	2,48	neutral	-2,53	neutral	-1,97	high_impact	4,29	neutral	0,87	damaging	0,11	deleterious	3,24	22,8	0,21	0,45	disease	0,65	disease	0,54	disease	0,63	disease	0,63	3	deleterious	0,99	neutral	0,28	deleterious	2	deleterious	0,76	low_impact	-2,59	medium_impact	0,27	high_impact	2,7	0,4	0,8	59,47	8,53	N	0,31	N	0,91	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15648	15648	T	G	MI.10247	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	902	301	L	R	cTa/cGa	-0,29	0	0	probably_damaging	1	neutral	0,17	neutral	2,37	deleterious	-5,09	deleterious	-3,94	high_impact	5,26	neutral	0,87	damaging	0,06	deleterious	4,24	23,9	0,03	0,35	disease	0,94	disease	0,84	disease	0,75	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,15	high_impact	3,58	0,12	0,8	59,47	8,53	P	0,69	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15648	15648	T	A	MI.10248	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	902	301	L	Q	cTa/cAa	-0,29	0	0	probably_damaging	1	neutral	0,13	neutral	2,37	deleterious	-5,19	deleterious	-3,94	high_impact	4,92	neutral	0,86	damaging	0,07	deleterious	4,15	23,8	0,04	0,35	disease	0,94	disease	0,71	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,23	high_impact	3,27	0,22	0,8	59,47	8,53	P	0,62	P	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15648	15648	T	C	MI.10249	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	902	301	L	P	cTa/cCa	-0,29	0	0	probably_damaging	1	neutral	0,19	neutral	2,36	deleterious	-5,43	deleterious	-4,6	high_impact	4,22	neutral	0,87	damaging	0,05	deleterious	4	23,6	0,03	0,35	disease	0,95	disease	0,73	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,12	high_impact	2,64	0,23	0,8	59,47	8,53	N	0,4	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9008	9008	C	G	MI.1025	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	482	161	T	S	aCc/aGc	7,07	1	0	probably_damaging	0,99	neutral	0,1	neutral	4,27	neutral	-0,63	deleterious	-3,59	medium_impact	2,08	damaging	0,6	neutral	0,64	deleterious	3,56	23,1	0,48	0,65	disease	0,67	disease	0,71	disease	0,52	disease	0,56	1	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,76	low_impact	-2,65	medium_impact	-0,25	medium_impact	0,69	0,78	0,9	50,44	8,87	P	0,52	P	0,88	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15650	15650	G	A	MI.10250	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	904	302	A	T	Gca/Aca	-2,58	0	0	benign	0	neutral	0,18	neutral	2,88	neutral	-1,45	neutral	-0,21	low_impact	1,42	neutral	0,92	neutral	0,88	deleterious	2,69	20,7	0,22	0,45	neutral	0,37	neutral	0,36	neutral	0,4	neutral	0,46	1	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,16	high_impact	2,07	medium_impact	-0,14	medium_impact	0,1	0,71	0,85	17,37	20,13	N	0,44	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15650	15650	G	C	MI.10251	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	904	302	A	P	Gca/Cca	-2,58	0	0	benign	0,27	neutral	0,14	neutral	2,83	deleterious	-3,33	neutral	-1,35	medium_impact	2,97	neutral	0,84	neutral	0,29	deleterious	2,64	20,4	0,05	0,35	disease	0,64	disease	0,86	disease	0,64	disease	0,77	5	neutral	0,83	neutral	0,44	neutral	-3	deleterious	0,71	medium_impact	-0,33	medium_impact	-0,21	medium_impact	1,5	0,46	0,8	17,37	20,13	N	0,3	N	0,85	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15650	15650	G	T	MI.10252	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	904	302	A	S	Gca/Tca	-2,58	0	0	benign	0,1	neutral	0,29	neutral	2,87	neutral	-1,78	neutral	-0,44	low_impact	1,87	neutral	0,89	neutral	0,53	deleterious	2,15	17,21	0,27	0,45	neutral	0,41	neutral	0,48	neutral	0,49	neutral	0,49	0	neutral	0,67	deleterious	0,6	neutral	-6	neutral	0,23	medium_impact	0,16	medium_impact	0,01	medium_impact	0,51	0,36	0,8	17,37	20,13	N	0,38	N	0,61	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15651	15651	C	T	MI.10253	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	905	302	A	V	gCa/gTa	-2,58	0	0	benign	0	neutral	0,35	neutral	2,96	neutral	-0,35	neutral	0,77	neutral_impact	0,78	neutral	0,94	neutral	0,86	deleterious	2,4	18,81	0,17	0,45	neutral	0,29	disease	0,59	neutral	0,3	neutral	0,34	3	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,17	high_impact	2,07	medium_impact	0,08	medium_impact	-0,49	0,68	0,85	17,37	20,13	N	0,37	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15651	15651	C	A	MI.10254	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	905	302	A	E	gCa/gAa	-2,58	0	0	benign	0,29	neutral	0,1	neutral	2,84	neutral	-2,78	neutral	-1,2	medium_impact	3,31	neutral	0,82	neutral	0,43	deleterious	3,37	22,9	0,04	0,35	neutral	0,49	disease	0,8	disease	0,62	disease	0,74	5	neutral	0,88	neutral	0,41	neutral	-3	deleterious	0,54	medium_impact	-0,37	medium_impact	-0,3	medium_impact	1,81	0,28	0,8	17,37	20,13	N	0,32	N	0,84	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15651	15651	C	G	MI.10255	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	905	302	A	G	gCa/gGa	-2,58	0	0	benign	0,04	neutral	0,13	neutral	2,84	neutral	-2,82	neutral	-1,53	low_impact	1,73	neutral	0,9	neutral	0,53	neutral	1,06	11,02	0,22	0,45	disease	0,56	disease	0,54	neutral	0,5	neutral	0,46	1	neutral	0,86	deleterious	0,55	neutral	-6	neutral	0,26	medium_impact	0,56	medium_impact	-0,23	medium_impact	0,38	0,48	0,8	17,37	20,13	N	0,38	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15653	15653	A	G	MI.10256	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	907	303	M	V	Ata/Gta	-7,85	0	0,01	benign	0	neutral	0,64	neutral	3,13	neutral	1,57	neutral	0,16	neutral_impact	-1,01	neutral	0,94	neutral	0,98	neutral	-0,4	0,38	0,25	0,45	neutral	0,16	neutral	0,24	neutral	0,37	neutral	0,41	2	neutral	0,35	deleterious	0,82	neutral	-6	neutral	0,13	high_impact	2,07	medium_impact	0,36	low_impact	-2,11	0,23	0,8	20,79	19,17	N	0,33	N	0,01	polymorphism	1	0,01	rs878890251	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15653	15653	A	C	MI.10257	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	907	303	M	L	Ata/Cta	-7,85	0	0,01	benign	0,02	neutral	1	neutral	3,25	neutral	2,72	neutral	0,52	neutral_impact	-2,21	neutral	0,93	neutral	0,95	neutral	-1,16	0,01	0,25	0,45	neutral	0,25	neutral	0,17	neutral	0,32	neutral	0,23	5	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,12	medium_impact	0,85	high_impact	1,85	low_impact	-3,2	0,19	0,8	20,79	19,17	N	0,33	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15653	15653	A	T	MI.10258	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	907	303	M	L	Ata/Tta	-7,85	0	0,01	benign	0,02	neutral	1	neutral	3,25	neutral	2,72	neutral	0,52	neutral_impact	-2,21	neutral	0,93	neutral	0,95	neutral	-1	0,02	0,25	0,45	neutral	0,25	neutral	0,17	neutral	0,32	neutral	0,23	5	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,12	medium_impact	0,85	high_impact	1,85	low_impact	-3,2	0,19	0,8	20,79	19,17	N	0,33	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15654	15654	T	C	MI.10259	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	908	303	M	T	aTa/aCa	-13,58	0	0	benign	0	neutral	0,31	neutral	3,03	neutral	0,2	neutral	-1,43	neutral_impact	-0,05	neutral	0,92	neutral	0,83	deleterious	0,12	3,87	0,11	0,4	neutral	0,18	neutral	0,28	neutral	0,39	neutral	0,42	2	neutral	0,69	deleterious	0,66	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	0,03	low_impact	-1,24	0,1	0,8	20,79	19,17	N	0,39	N	0,02	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	9008	9008	C	T	MI.1026	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	482	161	T	I	aCc/aTc	7,07	1	0	probably_damaging	1	neutral	0,12	neutral	4,28	neutral	-0,31	deleterious	-5,43	medium_impact	2,78	neutral	0,69	neutral	0,62	deleterious	3,97	23,6	0,4	0,65	disease	0,55	disease	0,87	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	-0,2	medium_impact	1,29	0,7	0,9	50,44	8,87	N	0,46	N	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15654	15654	T	A	MI.10260	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	908	303	M	K	aTa/aAa	-13,58	0	0	benign	0,11	neutral	0,25	neutral	2,97	neutral	-1,38	neutral	-2,44	low_impact	1,9	neutral	0,82	neutral	0,51	deleterious	2,36	18,58	0,03	0,35	neutral	0,4	disease	0,64	disease	0,64	disease	0,7	4	neutral	0,71	deleterious	0,57	neutral	-6	neutral	0,27	medium_impact	0,12	medium_impact	-0,04	medium_impact	0,53	0,17	0,8	20,79	19,17	N	0,33	N	0,24	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15655	15655	A	C	MI.10261	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	909	303	M	I	atA/atC	1,08	0	0	benign	0,04	neutral	0,57	neutral	3,1	neutral	1,53	neutral	0,42	neutral_impact	-1,55	neutral	0,93	neutral	0,98	neutral	-0,68	0,08	0,25	0,45	neutral	0,19	neutral	0,22	neutral	0,29	neutral	0,38	2	neutral	0,38	deleterious	0,77	neutral	-6	neutral	0,14	medium_impact	0,56	medium_impact	0,29	low_impact	-2,6	0,26	0,8	20,79	19,17	N	0,37	N	0,02	disease_causing	1	0,01	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15655	15655	A	T	MI.10262	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	909	303	M	I	atA/atT	1,08	0	0	benign	0,04	neutral	0,57	neutral	3,1	neutral	1,53	neutral	0,42	neutral_impact	-1,55	neutral	0,93	neutral	0,98	neutral	-0,62	0,11	0,25	0,45	neutral	0,19	neutral	0,22	neutral	0,29	neutral	0,38	2	neutral	0,38	deleterious	0,77	neutral	-6	neutral	0,14	medium_impact	0,56	medium_impact	0,29	low_impact	-2,6	0,26	0,8	20,79	19,17	N	0,37	N	0,02	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15656	15656	A	T	MI.10263	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	910	304	I	F	Atc/Ttc	-16,1	0	0	possibly_damaging	0,84	neutral	0,57	neutral	2,99	neutral	-0,08	neutral	-1,91	low_impact	0,88	neutral	0,97	neutral	0,84	deleterious	2,01	16,31	0,18	0,45	neutral	0,38	neutral	0,49	neutral	0,42	neutral	0,45	1	neutral	0,81	neutral	0,37	neutral	-3	deleterious	0,66	low_impact	-1,4	medium_impact	0,29	medium_impact	-0,39	0,42	0,8	10,79	21,01	N	0,3	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15656	15656	A	C	MI.10264	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	910	304	I	L	Atc/Ctc	-16,1	0	0	benign	0,23	neutral	0,97	neutral	3,39	neutral	2,15	neutral	-0,66	neutral_impact	-0,41	neutral	0,94	neutral	0,9	deleterious	0,33	5,98	0,24	0,45	neutral	0,16	neutral	0,29	neutral	0,29	neutral	0,44	1	neutral	0,17	deleterious	0,87	neutral	-6	neutral	0,19	medium_impact	-0,24	medium_impact	1,04	low_impact	-1,57	0,49	0,8	10,79	21,01	N	0,33	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15656	15656	A	G	MI.10265	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	910	304	I	V	Atc/Gtc	-16,1	0	0	benign	0,1	neutral	0,73	neutral	3,07	neutral	0,67	neutral	0	neutral_impact	-0,05	neutral	0,98	neutral	0,92	neutral	-1,17	0,01	0,4	0,5	neutral	0,25	neutral	0,06	neutral	0,35	neutral	0,23	5	neutral	0,16	deleterious	0,82	neutral	-6	neutral	0,15	medium_impact	0,16	medium_impact	0,46	low_impact	-1,24	0,37	0,8	10,79	21,01	N	0,4	N	0,59	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15657	15657	T	A	MI.10266	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	911	304	I	N	aTc/aAc	-1,44	0	0	possibly_damaging	0,81	neutral	0,26	neutral	2,89	neutral	-2,68	deleterious	-3,35	medium_impact	2,79	neutral	0,93	neutral	0,51	deleterious	4,68	24,5	0,19	0,45	disease	0,71	disease	0,63	disease	0,64	disease	0,7	4	neutral	0,86	neutral	0,23	NA	0	deleterious	0,71	low_impact	-1,32	medium_impact	-0,02	medium_impact	1,34	0,22	0,8	10,79	21,01	N	0,4	N	0,86	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15657	15657	T	G	MI.10267	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	911	304	I	S	aTc/aGc	-1,44	0	0	possibly_damaging	0,61	neutral	0,68	neutral	2,92	neutral	-1,4	deleterious	-2,66	medium_impact	2,64	neutral	0,97	neutral	0,52	deleterious	4,29	24	0,08	0,35	disease	0,54	disease	0,58	disease	0,54	disease	0,58	2	neutral	0,53	deleterious	0,54	NA	0	deleterious	0,6	medium_impact	-0,91	medium_impact	0,4	medium_impact	1,2	0,17	0,8	10,79	21,01	N	0,22	N	0,79	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15657	15657	T	C	MI.10268	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	911	304	I	T	aTc/aCc	-1,44	0	0	benign	0,07	neutral	0,29	neutral	2,93	neutral	-1,12	neutral	-1,84	medium_impact	2,13	neutral	0,98	neutral	0,7	deleterious	3,35	22,9	0,14	0,4	neutral	0,47	neutral	0,35	neutral	0,43	neutral	0,46	1	neutral	0,68	deleterious	0,61	neutral	-3	neutral	0,19	medium_impact	0,32	medium_impact	0,01	medium_impact	0,74	0,19	0,8	10,79	21,01	N	0,45	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15658	15658	C	A	MI.10269	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	912	304	I	M	atC/atA	2,46	0,04	0	probably_damaging	0,92	neutral	0,17	neutral	2,95	neutral	-0,78	neutral	-0,71	neutral_impact	0,08	neutral	0,96	neutral	0,9	deleterious	2,01	16,26	0,33	0,5	neutral	0,26	neutral	0,23	neutral	0,31	neutral	0,42	2	neutral	0,96	neutral	0,13	neutral	-2	deleterious	0,64	low_impact	-1,72	medium_impact	-0,15	low_impact	-1,12	0,49	0,8	10,79	21,01	N	0,52	P	0,26	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	9010	9010	G	A	MI.1027	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	484	162	A	T	Gct/Act	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	3,46	deleterious	-4,91	deleterious	-3,55	high_impact	3,62	damaging	0,47	neutral	0,43	deleterious	4,32	24	0,37	0,65	disease	0,88	disease	0,85	disease	0,67	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,01	0,75	0,9	49,56	8,89	N	0,35	N	0,8	disease_causing	0,65	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15658	15658	C	G	MI.10270	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	912	304	I	M	atC/atG	2,46	0,04	0	probably_damaging	0,92	neutral	0,17	neutral	2,95	neutral	-0,78	neutral	-0,71	neutral_impact	0,08	neutral	0,96	neutral	0,9	neutral	1,57	13,71	0,33	0,5	neutral	0,26	neutral	0,23	neutral	0,31	neutral	0,42	2	neutral	0,96	neutral	0,13	neutral	-2	deleterious	0,64	low_impact	-1,72	medium_impact	-0,15	low_impact	-1,12	0,49	0,8	10,79	21,01	N	0,53	P	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15659	15659	C	G	MI.10271	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	913	305	P	A	Ccc/Gcc	-6,94	0	0	probably_damaging	1	neutral	0,43	neutral	1,38	deleterious	-6,19	deleterious	-5,17	high_impact	4,01	neutral	0,87	damaging	0,11	deleterious	2,97	22,1	0,16	0,45	neutral	0,5	disease	0,6	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,75	low_impact	-3,53	medium_impact	0,16	high_impact	2,45	0,46	0,8	55	8,37	N	0,32	N	0,84	polymorphism	1	0,11	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15659	15659	C	A	MI.10272	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	913	305	P	T	Ccc/Acc	-6,94	0	0	probably_damaging	1	neutral	0,35	neutral	1,35	deleterious	-7,4	deleterious	-5,17	high_impact	4,95	neutral	0,82	damaging	0,08	deleterious	3,74	23,3	0,14	0,4	disease	0,55	disease	0,77	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,08	high_impact	3,3	0,33	0,8	55	8,37	P	0,57	P	0,96	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15659	15659	C	T	MI.10273	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	913	305	P	S	Ccc/Tcc	-6,94	0	0	probably_damaging	1	neutral	0,49	neutral	1,38	deleterious	-6,14	deleterious	-5,17	high_impact	3,6	neutral	0,84	damaging	0,07	deleterious	3,96	23,6	0,15	0,45	disease	0,53	disease	0,77	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,21	high_impact	2,08	0,12	0,8	55	8,37	N	0,24	N	0,9	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15660	15660	C	A	MI.10274	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	914	305	P	H	cCc/cAc	7,04	1	0	probably_damaging	1	neutral	0,44	neutral	1,34	deleterious	-8,9	deleterious	-5,83	high_impact	5,29	neutral	0,84	damaging	0,07	deleterious	4,13	23,8	0,09	0,35	disease	0,73	disease	0,84	disease	0,79	disease	0,69	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,17	high_impact	3,61	0,23	0,8	55	8,37	P	0,7	P	0,71	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15660	15660	C	G	MI.10275	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	914	305	P	R	cCc/cGc	7,04	1	0	probably_damaging	1	neutral	0,33	neutral	1,35	deleterious	-7,83	deleterious	-5,83	high_impact	5,29	neutral	0,82	damaging	0,05	deleterious	3,68	23,3	0,06	0,35	neutral	0,45	disease	0,88	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,06	high_impact	3,61	0,24	0,8	55	8,37	P	0,66	P	0,8	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15660	15660	C	T	MI.10276	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	914	305	P	L	cCc/cTc	7,04	1	0	probably_damaging	1	neutral	1	neutral	1,36	deleterious	-7,06	deleterious	-6,47	high_impact	4,32	neutral	0,85	damaging	0,05	deleterious	4,5	24,3	0,07	0,35	disease	0,53	disease	0,84	disease	0,66	disease	0,69	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,8	low_impact	-3,53	high_impact	1,85	high_impact	2,73	0,64	0,8	55	8,37	N	0,44	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15662	15662	A	G	MI.10277	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	916	306	I	V	Atc/Gtc	-12,9	0	0,06	benign	0	neutral	0,5	neutral	3,16	neutral	-0,03	neutral	-0,39	neutral_impact	0,51	neutral	0,98	neutral	0,88	deleterious	0,27	5,4	0,4	0,5	neutral	0,22	neutral	0,23	neutral	0,37	neutral	0,43	1	neutral	0,5	deleterious	0,75	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	0,22	medium_impact	-0,73	0,24	0,8	18,95	20,19	N	0,39	N	0,01	polymorphism	1	0,01	rs3094280	.	.	.	.	breast tumor	.	.	0,59	A15662G	Complex mitochondriopathy-associated	+	+	Reported	1
chrM	15662	15662	A	C	MI.10278	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	916	306	I	L	Atc/Ctc	-12,9	0	0,06	benign	0,01	neutral	0,66	neutral	3,27	neutral	0,99	neutral	0,04	neutral_impact	-0,94	neutral	0,97	neutral	0,94	neutral	-0,6	0,12	0,28	0,45	neutral	0,16	neutral	0,15	neutral	0,24	neutral	0,23	5	neutral	0,32	deleterious	0,83	neutral	-6	neutral	0,12	medium_impact	1,13	medium_impact	0,38	low_impact	-2,05	0,4	0,8	18,95	20,19	N	0,39	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15662	15662	A	T	MI.10279	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	916	306	I	F	Atc/Ttc	-12,9	0	0,06	benign	0,17	neutral	0,7	neutral	3,31	neutral	0,77	neutral	-0,98	neutral_impact	-1,16	neutral	0,98	neutral	0,93	deleterious	2,11	16,89	0,22	0,45	neutral	0,18	neutral	0,27	neutral	0,25	neutral	0,44	1	neutral	0,18	deleterious	0,77	neutral	-6	neutral	0,24	medium_impact	-0,09	medium_impact	0,42	low_impact	-2,25	0,49	0,8	18,95	20,19	N	0,43	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9010	9010	G	T	MI.1028	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	484	162	A	S	Gct/Tct	-6,12	0	0	probably_damaging	0,99	deleterious	0,02	neutral	3,47	deleterious	-4,28	deleterious	-2,66	high_impact	3,62	damaging	0,51	neutral	0,57	deleterious	3,81	23,4	0,3	0,65	disease	0,76	disease	0,86	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-2,65	medium_impact	-0,66	high_impact	2,01	0,76	0,9	49,56	8,89	N	0,36	N	0,95	polymorphism	0,55	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15663	15663	T	C	MI.10280	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	917	306	I	T	aTc/aCc	-14,27	0	0	benign	0	neutral	0,39	neutral	3,13	neutral	-1,15	neutral	-1,66	neutral_impact	0,79	neutral	1	neutral	0,89	deleterious	0,83	9,68	0,22	0,45	neutral	0,33	neutral	0,32	disease	0,52	neutral	0,48	0	neutral	0,61	deleterious	0,7	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	0,12	medium_impact	-0,48	0,16	0,8	18,95	20,19	N	0,39	N	0,08	polymorphism	1	0,02	rs369851331	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15663	15663	T	G	MI.10281	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	917	306	I	S	aTc/aGc	-14,27	0	0	benign	0,07	neutral	0,4	neutral	3,11	neutral	-1,27	neutral	-2,09	medium_impact	2,06	neutral	0,97	neutral	0,62	deleterious	4,02	23,6	0,05	0,35	neutral	0,4	disease	0,54	disease	0,6	disease	0,61	2	neutral	0,55	deleterious	0,67	neutral	-3	neutral	0,2	medium_impact	0,32	medium_impact	0,13	medium_impact	0,68	0,14	0,8	18,95	20,19	N	0,29	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15663	15663	T	A	MI.10282	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	917	306	I	N	aTc/aAc	-14,27	0	0	benign	0,17	neutral	0,31	neutral	3,09	neutral	-2,62	deleterious	-2,87	medium_impact	2,96	neutral	0,93	neutral	0,55	deleterious	4,29	24	0,13	0,4	neutral	0,38	disease	0,54	disease	0,63	disease	0,68	4	neutral	0,63	deleterious	0,57	neutral	-3	neutral	0,27	medium_impact	-0,09	medium_impact	0,03	medium_impact	1,49	0,15	0,8	18,95	20,19	N	0,37	N	0,32	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15664	15664	C	A	MI.10283	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	918	306	I	M	atC/atA	1,08	0	0	benign	0,02	neutral	0,22	neutral	3,12	neutral	-1,33	neutral	-0,38	neutral_impact	-0,03	neutral	0,94	neutral	0,91	deleterious	2,08	16,7	0,37	0,5	neutral	0,28	neutral	0,18	neutral	0,3	neutral	0,34	3	neutral	0,77	deleterious	0,6	neutral	-6	neutral	0,14	medium_impact	0,85	medium_impact	-0,08	low_impact	-1,22	0,49	0,8	18,95	20,19	N	0,46	N	0,01	polymorphism	1	0,01	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15664	15664	C	G	MI.10284	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	918	306	I	M	atC/atG	1,08	0	0	benign	0,02	neutral	0,22	neutral	3,12	neutral	-1,33	neutral	-0,38	neutral_impact	-0,03	neutral	0,94	neutral	0,91	neutral	1,6	13,86	0,37	0,5	neutral	0,28	neutral	0,18	neutral	0,3	neutral	0,34	3	neutral	0,77	deleterious	0,6	neutral	-6	neutral	0,14	medium_impact	0,85	medium_impact	-0,08	low_impact	-1,22	0,49	0,8	18,95	20,19	N	0,46	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15665	15665	C	G	MI.10285	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	919	307	L	V	Ctc/Gtc	-13,81	0	0	probably_damaging	0,98	neutral	0,4	neutral	2,78	neutral	-2,07	neutral	-1,75	medium_impact	2,83	neutral	0,94	damaging	0,19	deleterious	1,86	15,36	0,29	0,45	neutral	0,39	disease	0,71	neutral	0,41	neutral	0,36	3	neutral	0,98	neutral	0,21	deleterious	1	deleterious	0,73	low_impact	-2,31	medium_impact	0,13	medium_impact	1,38	0,39	0,8	21,58	13,46	N	0,26	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15665	15665	C	T	MI.10286	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	919	307	L	F	Ctc/Ttc	-13,81	0	0	probably_damaging	1	neutral	0,74	neutral	2,69	deleterious	-3,01	neutral	-2,44	medium_impact	3,26	neutral	0,96	damaging	0,13	deleterious	3,94	23,5	0,17	0,45	neutral	0,43	disease	0,71	neutral	0,45	neutral	0,34	3	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,77	low_impact	-3,53	medium_impact	0,47	medium_impact	1,77	0,41	0,8	21,58	13,46	N	0,2	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15665	15665	C	A	MI.10287	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	919	307	L	I	Ctc/Atc	-13,81	0	0	probably_damaging	0,99	neutral	0,62	neutral	2,77	neutral	-1,49	neutral	-1,16	low_impact	1,89	neutral	0,96	neutral	0,7	deleterious	2,74	21	0,33	0,5	neutral	0,38	disease	0,71	neutral	0,37	neutral	0,2	6	deleterious	0,99	neutral	0,32	neutral	-2	deleterious	0,73	low_impact	-2,59	medium_impact	0,34	medium_impact	0,52	0,36	0,8	21,58	13,46	N	0,24	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15666	15666	T	A	MI.10288	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	920	307	L	H	cTc/cAc	0,86	0,27	0	probably_damaging	1	neutral	0,44	neutral	2,64	deleterious	-5,08	deleterious	-4,29	high_impact	4,59	neutral	0,93	damaging	0,09	deleterious	4,2	23,9	0,06	0,35	disease	0,82	disease	0,83	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,17	high_impact	2,97	0,19	0,8	21,58	13,46	N	0,49	N	0,95	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15666	15666	T	G	MI.10289	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	920	307	L	R	cTc/cGc	0,86	0,27	0	probably_damaging	1	neutral	0,27	neutral	2,66	deleterious	-4,27	deleterious	-3,68	high_impact	4,39	neutral	0,94	damaging	0,07	deleterious	4,24	23,9	0,03	0,35	disease	0,77	disease	0,92	disease	0,76	disease	0,75	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,01	high_impact	2,79	0,13	0,8	21,58	13,46	N	0,51	P	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9010	9010	G	C	MI.1029	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	484	162	A	P	Gct/Cct	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	3,43	deleterious	-5,82	deleterious	-4,54	high_impact	4,25	damaging	0,4	neutral	0,44	deleterious	3,97	23,6	0,16	0,65	disease	0,95	disease	0,9	disease	0,77	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	high_impact	2,54	0,61	0,9	49,56	8,89	P	0,62	P	0,97	disease_causing	0,87	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15666	15666	T	C	MI.10290	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	920	307	L	P	cTc/cCc	0,86	0,27	0	probably_damaging	1	neutral	0,3	neutral	2,64	deleterious	-4,5	deleterious	-4,28	high_impact	4,39	neutral	0,93	damaging	0,07	deleterious	3,97	23,6	0,02	0,35	disease	0,82	disease	0,86	disease	0,76	disease	0,72	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,02	high_impact	2,79	0,23	0,8	21,58	13,46	N	0,5	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15668	15668	C	A	MI.10291	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	922	308	H	N	Cat/Aat	-20	0	0	probably_damaging	1	neutral	0,33	neutral	3,15	neutral	0,75	deleterious	-4,4	medium_impact	2,12	neutral	0,89	damaging	0,18	deleterious	3,7	23,3	0,31	0,45	neutral	0,32	disease	0,68	disease	0,54	neutral	0,26	5	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,71	low_impact	-3,53	medium_impact	0,06	medium_impact	0,73	0,26	0,8	53,42	10,01	N	0,32	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15668	15668	C	G	MI.10292	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	922	308	H	D	Cat/Gat	-20	0	0	probably_damaging	1	neutral	0,22	neutral	3,29	neutral	3,37	deleterious	-5,71	low_impact	1,77	neutral	0,84	damaging	0,09	deleterious	3,82	23,4	0,05	0,35	neutral	0,2	disease	0,83	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,71	low_impact	-3,53	medium_impact	-0,08	medium_impact	0,41	0,35	0,8	53,42	10,01	N	0,26	N	0,98	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15668	15668	C	T	MI.10293	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	922	308	H	Y	Cat/Tat	-20	0	0	probably_damaging	1	neutral	1	neutral	3,07	neutral	-0,8	deleterious	-3,83	medium_impact	3,25	neutral	0,91	damaging	0,13	deleterious	3,49	23,1	0,2	0,45	neutral	0,39	disease	0,8	disease	0,65	disease	0,55	1	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,75	low_impact	-3,53	high_impact	1,85	medium_impact	1,76	0,21	0,8	53,42	10,01	N	0,19	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15669	15669	A	C	MI.10294	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	923	308	H	P	cAt/cCt	5,44	1	0	probably_damaging	1	neutral	0,24	neutral	3,08	neutral	-0,76	deleterious	-6,37	high_impact	3,71	neutral	0,88	damaging	0,08	deleterious	3,21	22,7	0,04	0,35	neutral	0,49	disease	0,87	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	-0,05	high_impact	2,18	0,17	0,8	53,42	10,01	N	0,46	N	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15669	15669	A	G	MI.10295	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	923	308	H	R	cAt/cGt	5,44	1	0	probably_damaging	1	neutral	0,39	neutral	3,11	neutral	0,55	deleterious	-5,08	high_impact	4,2	neutral	0,87	damaging	0,09	deleterious	2,81	21,4	0,13	0,4	neutral	0,34	disease	0,87	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	0,12	high_impact	2,62	0,23	0,8	53,42	10,01	N	0,42	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15669	15669	A	T	MI.10296	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	923	308	H	L	cAt/cTt	5,44	1	0	probably_damaging	1	neutral	0,87	neutral	3,1	neutral	0,31	deleterious	-7,01	high_impact	3,94	neutral	0,88	damaging	0,1	deleterious	3,68	23,3	0,07	0,35	neutral	0,47	disease	0,86	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	0,67	high_impact	2,38	0,14	0,8	53,42	10,01	N	0,43	N	0,92	polymorphism	1	0,05	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15670	15670	T	A	MI.10297	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	924	308	H	Q	caT/caA	8,42	1	0,02	probably_damaging	1	neutral	0,3	neutral	3,08	neutral	0,73	deleterious	-5,06	high_impact	3,94	neutral	0,96	neutral	0,52	deleterious	3,39	23	0,22	0,45	neutral	0,29	disease	0,73	disease	0,55	neutral	0,27	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,72	low_impact	-3,53	medium_impact	0,02	high_impact	2,38	0,27	0,8	53,42	10,01	P	0,6	P	0,94	polymorphism	1	0,05	rs193302997	Likely pathogenic	Neoplasm_of_ovary	RCV000133458.1	Gene:MedGen:OMIM:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	15670	15670	T	G	MI.10298	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	924	308	H	Q	caT/caG	8,42	1	0,02	probably_damaging	1	neutral	0,3	neutral	3,08	neutral	0,73	deleterious	-5,06	high_impact	3,94	neutral	0,96	neutral	0,52	deleterious	3,3	22,9	0,22	0,45	neutral	0,29	disease	0,73	disease	0,55	neutral	0,27	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,72	low_impact	-3,53	medium_impact	0,02	high_impact	2,38	0,27	0,8	53,42	10,01	P	0,59	P	0,94	polymorphism	1	0,05	rs193302997	Likely pathogenic	Neoplasm_of_ovary	RCV000133458.1	Gene:MedGen:OMIM:SNOMED_CT	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15671	15671	A	G	MI.10299	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	925	309	M	V	Ata/Gta	-2,35	0	0	benign	0	neutral	0,5	neutral	3,22	neutral	1,08	neutral	0,15	neutral_impact	0,74	neutral	0,97	neutral	0,89	deleterious	0,8	9,49	0,25	0,45	neutral	0,24	disease	0,7	neutral	0,31	neutral	0,5	0	neutral	0,5	deleterious	0,75	neutral	-6	neutral	0,19	high_impact	2,07	medium_impact	0,22	medium_impact	-0,52	0,18	0,8	23,16	41,47	N	0,29	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8573	8573	G	C	MI.103	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	47	16	G	A	gGc/gCc	6,14	1	0	possibly_damaging	0,64	neutral	0,08	neutral	4,66	neutral	0,1	deleterious	-4,82	medium_impact	3,12	neutral	0,81	neutral	0,37	deleterious	2,57	19,9	0,46	0,65	neutral	0,5	disease	0,68	disease	0,61	disease	0,61	2	neutral	0,92	neutral	0,22	NA	0	deleterious	0,64	medium_impact	-0,99	medium_impact	-0,31	medium_impact	1,58	0,7	0,9	17,26	11,64	P	0,57	P	0,76	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9011	9011	C	G	MI.1030	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	485	162	A	G	gCt/gGt	9,38	1	0	probably_damaging	0,99	deleterious	0,01	neutral	3,78	neutral	-1,56	deleterious	-3,6	medium_impact	3,49	damaging	0,53	neutral	0,53	deleterious	4,08	23,7	0,27	0,65	neutral	0,45	disease	0,83	disease	0,62	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,77	low_impact	-2,65	medium_impact	-0,84	medium_impact	1,89	0,85	0,9	49,56	8,89	P	0,51	P	0,86	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15671	15671	A	C	MI.10300	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	925	309	M	L	Ata/Cta	-2,35	0	0	benign	0,02	neutral	0,66	neutral	3,26	neutral	1,36	neutral	-0,22	neutral_impact	-0,4	neutral	0,97	neutral	0,95	deleterious	0,18	4,44	0,24	0,45	neutral	0,19	disease	0,54	neutral	0,26	neutral	0,35	3	neutral	0,3	deleterious	0,82	neutral	-6	neutral	0,17	medium_impact	0,85	medium_impact	0,38	low_impact	-1,56	0,2	0,8	23,16	41,47	N	0,33	N	0,16	polymorphism	1	0	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15671	15671	A	T	MI.10301	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	925	309	M	L	Ata/Tta	-2,35	0	0	benign	0,02	neutral	0,66	neutral	3,26	neutral	1,36	neutral	-0,22	neutral_impact	-0,4	neutral	0,97	neutral	0,95	deleterious	0,28	5,47	0,24	0,45	neutral	0,19	disease	0,54	neutral	0,26	neutral	0,35	3	neutral	0,3	deleterious	0,82	neutral	-6	neutral	0,17	medium_impact	0,85	medium_impact	0,38	low_impact	-1,56	0,2	0,8	23,16	41,47	N	0,34	N	0,16	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15672	15672	T	C	MI.10302	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	926	309	M	T	aTa/aCa	5,44	0,54	0,01	benign	0	neutral	0,41	neutral	3,3	neutral	1,93	neutral	2,4	neutral_impact	-2,31	neutral	1	neutral	0,98	neutral	-1,5	0	0,21	0,45	neutral	0,19	neutral	0,2	neutral	0,24	neutral	0,33	3	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,14	low_impact	-3,29	0,09	0,8	23,16	41,47	N	0,32	N	0,1	polymorphism	1	0	rs199967113	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15672	15672	T	A	MI.10303	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	926	309	M	K	aTa/aAa	5,44	0,54	0,01	benign	0,07	neutral	0,29	neutral	3,23	neutral	2,02	neutral	-0,06	neutral_impact	-1,04	neutral	0,96	neutral	0,74	neutral	1,14	11,41	0,08	0,35	neutral	0,19	disease	0,76	neutral	0,33	neutral	0,44	1	neutral	0,68	deleterious	0,61	neutral	-6	neutral	0,21	medium_impact	0,32	medium_impact	0,01	low_impact	-2,14	0,13	0,8	23,16	41,47	N	0,36	N	0,25	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15673	15673	A	C	MI.10304	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	927	309	M	I	atA/atC	-0,29	0	0	benign	0,02	neutral	0,4	neutral	3,21	neutral	0,86	neutral	-0,34	low_impact	1	neutral	0,96	neutral	0,62	neutral	1,72	14,52	0,24	0,45	neutral	0,23	disease	0,74	neutral	0,44	neutral	0,49	0	neutral	0,58	deleterious	0,69	neutral	-6	neutral	0,2	medium_impact	0,85	medium_impact	0,13	medium_impact	-0,29	0,31	0,8	23,16	41,47	N	0,28	N	0,11	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15673	15673	A	T	MI.10305	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	927	309	M	I	atA/atT	-0,29	0	0	benign	0,02	neutral	0,4	neutral	3,21	neutral	0,86	neutral	-0,34	low_impact	1	neutral	0,96	neutral	0,62	neutral	1,75	14,7	0,24	0,45	neutral	0,23	disease	0,74	neutral	0,44	neutral	0,49	0	neutral	0,58	deleterious	0,69	neutral	-6	neutral	0,2	medium_impact	0,85	medium_impact	0,13	medium_impact	-0,29	0,31	0,8	23,16	41,47	N	0,28	N	0,11	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15674	15674	T	G	MI.10306	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	928	310	S	A	Tcc/Gcc	-1,67	0	0,02	benign	0,02	neutral	0,51	neutral	2,79	neutral	-1,77	neutral	-1,51	medium_impact	2,19	neutral	0,96	neutral	0,88	deleterious	2,18	17,37	0,23	0,45	neutral	0,37	neutral	0,46	neutral	0,41	neutral	0,39	2	neutral	0,47	deleterious	0,75	neutral	-3	neutral	0,17	medium_impact	0,85	medium_impact	0,23	medium_impact	0,8	0,46	0,8	20,26	12,07	N	0,32	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15674	15674	T	C	MI.10307	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	928	310	S	P	Tcc/Ccc	-1,67	0	0,02	possibly_damaging	0,68	neutral	0,21	neutral	2,72	neutral	-2,73	deleterious	-2,98	high_impact	3,68	neutral	0,76	neutral	0,34	deleterious	3,89	23,5	0,06	0,35	disease	0,7	disease	0,84	neutral	0,5	disease	0,67	3	neutral	0,83	neutral	0,27	deleterious	1	deleterious	0,56	low_impact	-1,04	medium_impact	-0,09	high_impact	2,15	0,25	0,8	20,26	12,07	N	0,49	N	1	polymorphism	1	0,04	.	.	.	.	.	breast tumor	.	.	.	T15674C	LHON	+	-	Reported	2
chrM	15674	15674	T	A	MI.10308	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	928	310	S	T	Tcc/Acc	-1,67	0	0,02	benign	0,19	neutral	0,41	neutral	2,77	neutral	-2,09	neutral	-1,71	high_impact	3,51	neutral	0,87	neutral	0,61	deleterious	2,16	17,24	0,17	0,45	neutral	0,47	disease	0,69	neutral	0,38	neutral	0,41	2	neutral	0,51	deleterious	0,61	neutral	-2	neutral	0,26	medium_impact	-0,14	medium_impact	0,14	medium_impact	1,99	0,52	0,8	20,26	12,07	N	0,33	N	0,7	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15675	15675	C	A	MI.10309	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	929	310	S	Y	tCc/tAc	1,31	0,87	0	probably_damaging	0,95	neutral	1	neutral	2,71	deleterious	-4,18	deleterious	-3,6	high_impact	4,2	neutral	0,91	neutral	0,46	deleterious	4,23	23,9	0,05	0,35	disease	0,63	disease	0,84	disease	0,67	disease	0,71	4	neutral	0,95	deleterious	0,53	deleterious	2	deleterious	0,76	low_impact	-1,92	high_impact	1,85	high_impact	2,62	0,24	0,8	20,26	12,07	N	0,3	N	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9011	9011	C	A	MI.1031	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	485	162	A	D	gCt/gAt	9,38	1	0	probably_damaging	1	deleterious	0	neutral	3,43	deleterious	-6,89	deleterious	-5,37	high_impact	4,59	damaging	0,55	neutral	0,46	deleterious	4,55	24,3	0,13	0,65	disease	0,97	disease	0,93	disease	0,75	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,84	0,62	0,9	49,56	8,89	P	0,52	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15675	15675	C	G	MI.10310	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	929	310	S	C	tCc/tGc	1,31	0,87	0	probably_damaging	0,92	neutral	0,18	neutral	2,7	deleterious	-4,44	deleterious	-2,91	medium_impact	3,24	neutral	0,84	neutral	0,37	deleterious	3,6	23,2	0,07	0,35	disease	0,75	disease	0,74	disease	0,55	disease	0,53	1	neutral	0,95	neutral	0,13	deleterious	1	deleterious	0,65	low_impact	-1,72	medium_impact	-0,14	medium_impact	1,75	0,3	0,8	20,26	12,07	N	0,34	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15675	15675	C	T	MI.10311	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	929	310	S	F	tCc/tTc	1,31	0,87	0	probably_damaging	0,95	neutral	0,72	neutral	2,71	deleterious	-3,84	deleterious	-3,61	high_impact	4,04	neutral	0,91	neutral	0,48	deleterious	4,23	23,9	0,05	0,35	disease	0,57	disease	0,84	disease	0,6	disease	0,68	4	neutral	0,95	neutral	0,39	deleterious	2	deleterious	0,75	low_impact	-1,92	medium_impact	0,44	high_impact	2,48	0,09	0,8	20,26	12,07	N	0,29	N	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15677	15677	A	C	MI.10312	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	931	311	K	Q	Aaa/Caa	-15,19	0	0	probably_damaging	0,99	neutral	0,6	neutral	2,94	neutral	-1,58	neutral	-2,42	high_impact	3,83	neutral	0,9	damaging	0,14	deleterious	1,93	15,79	0,26	0,45	neutral	0,47	disease	0,74	disease	0,66	disease	0,66	3	deleterious	0,99	neutral	0,31	deleterious	2	deleterious	0,74	low_impact	-2,59	medium_impact	0,32	high_impact	2,28	0,26	0,8	17,63	17,74	N	0,23	N	0,93	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15677	15677	A	G	MI.10313	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	931	311	K	E	Aaa/Gaa	-15,19	0	0	probably_damaging	0,99	neutral	0,76	neutral	2,97	neutral	-0,79	neutral	-2,43	high_impact	3,56	neutral	0,8	damaging	0,17	deleterious	3,71	23,3	0,18	0,45	neutral	0,36	disease	0,8	disease	0,65	disease	0,65	3	deleterious	0,99	neutral	0,39	deleterious	2	deleterious	0,76	low_impact	-2,59	medium_impact	0,49	high_impact	2,04	0,26	0,8	17,63	17,74	N	0,19	N	0,95	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15678	15678	A	C	MI.10314	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	932	311	K	T	aAa/aCa	4,52	0,99	0	probably_damaging	1	neutral	0,69	neutral	2,97	neutral	-1,63	deleterious	-3,6	medium_impact	3,14	neutral	0,91	damaging	0,17	deleterious	3,55	23,1	0,06	0,35	neutral	0,49	disease	0,77	disease	0,59	disease	0,55	1	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,78	low_impact	-3,53	medium_impact	0,41	medium_impact	1,66	0,16	0,8	17,63	17,74	N	0,39	N	0,88	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15678	15678	A	T	MI.10315	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	932	311	K	M	aAa/aTa	4,52	0,99	0	probably_damaging	1	neutral	0,27	neutral	2,92	deleterious	-3,65	deleterious	-3,66	high_impact	4,17	neutral	0,91	damaging	0,19	deleterious	4,07	23,7	0,07	0,35	disease	0,73	disease	0,78	disease	0,59	disease	0,66	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	-0,01	high_impact	2,59	0,17	0,8	17,63	17,74	P	0,55	P	0,67	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15679	15679	A	C	MI.10316	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	933	311	K	N	aaA/aaC	8,42	1	0	probably_damaging	1	neutral	0,58	neutral	2,98	neutral	-1,78	deleterious	-2,92	medium_impact	2,42	neutral	0,93	neutral	0,78	deleterious	2,75	21,1	0,38	0,5	neutral	0,41	disease	0,61	neutral	0,47	neutral	0,21	6	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,73	low_impact	-3,53	medium_impact	0,3	medium_impact	1	0,25	0,8	17,63	17,74	N	0,49	N	0,84	polymorphism	1	0,03	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15679	15679	A	T	MI.10317	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	933	311	K	N	aaA/aaT	8,42	1	0	probably_damaging	1	neutral	0,58	neutral	2,98	neutral	-1,78	deleterious	-2,92	medium_impact	2,42	neutral	0,93	neutral	0,78	deleterious	2,79	21,3	0,38	0,5	neutral	0,41	disease	0,61	neutral	0,47	neutral	0,21	6	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,73	low_impact	-3,53	medium_impact	0,3	medium_impact	1	0,25	0,8	17,63	17,74	N	0,5	N	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15680	15680	C	G	MI.10318	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	934	312	Q	E	Caa/Gaa	0,63	0,99	0	benign	0,41	neutral	0,31	neutral	2,99	neutral	-0,37	neutral	-1,65	high_impact	3,6	neutral	0,9	damaging	0,12	neutral	1,51	13,34	0,24	0,45	neutral	0,42	disease	0,66	disease	0,54	disease	0,59	2	neutral	0,64	neutral	0,45	neutral	-2	deleterious	0,46	medium_impact	-0,58	medium_impact	0,03	high_impact	2,08	0,27	0,8	31,58	10,28	N	0,4	N	0,93	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15680	15680	C	A	MI.10319	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	934	312	Q	K	Caa/Aaa	0,63	0,99	0	possibly_damaging	0,67	neutral	0,48	neutral	3,01	neutral	0,26	neutral	-2,14	medium_impact	3,12	neutral	0,92	damaging	0,1	deleterious	4,03	23,7	0,21	0,45	neutral	0,38	disease	0,8	disease	0,54	disease	0,62	2	neutral	0,65	neutral	0,41	NA	0	deleterious	0,68	low_impact	-1,02	medium_impact	0,2	medium_impact	1,64	0,23	0,8	31,58	10,28	N	0,33	N	1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9011	9011	C	T	MI.1032	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	485	162	A	V	gCt/gTt	9,38	1	0	probably_damaging	1	neutral	0,18	neutral	3,55	deleterious	-4,45	deleterious	-3,6	medium_impact	3,44	damaging	0,38	neutral	0,4	deleterious	4,5	24,3	0,37	0,65	disease	0,58	disease	0,87	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,08	medium_impact	1,85	0,84	0,9	49,56	8,89	P	0,76	P	0,75	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15681	15681	A	T	MI.10320	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	935	312	Q	L	cAa/cTa	4,29	1	0	possibly_damaging	0,82	neutral	0,7	neutral	3,15	neutral	2,18	deleterious	-3,42	low_impact	1,56	neutral	0,97	neutral	0,43	deleterious	3,59	23,2	0,09	0,35	neutral	0,27	disease	0,74	neutral	0,48	neutral	0,37	3	neutral	0,79	neutral	0,44	neutral	-3	deleterious	0,69	low_impact	-1,35	medium_impact	0,42	medium_impact	0,22	0,15	0,8	31,58	10,28	N	0,42	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15681	15681	A	C	MI.10321	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	935	312	Q	P	cAa/cCa	4,29	1	0	probably_damaging	0,92	neutral	0,24	neutral	2,98	neutral	-1,09	deleterious	-3,32	high_impact	4,5	neutral	0,9	damaging	0,07	deleterious	3,2	22,7	0,06	0,35	disease	0,64	disease	0,84	disease	0,57	disease	0,65	3	neutral	0,94	neutral	0,16	deleterious	2	deleterious	0,8	low_impact	-1,72	medium_impact	-0,05	high_impact	2,89	0,26	0,8	31,58	10,28	N	0,49	N	0,98	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15681	15681	A	G	MI.10322	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	935	312	Q	R	cAa/cGa	4,29	1	0	benign	0,3	neutral	0,39	neutral	2,99	neutral	-0,31	neutral	-2,12	high_impact	3,81	neutral	0,9	damaging	0,13	deleterious	3,4	23	0,22	0,45	neutral	0,48	disease	0,81	neutral	0,47	disease	0,52	0	neutral	0,53	deleterious	0,55	neutral	-2	neutral	0,33	medium_impact	-0,39	medium_impact	0,12	high_impact	2,27	0,24	0,8	31,58	10,28	N	0,48	N	0,99	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15682	15682	A	C	MI.10323	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	936	312	Q	H	caA/caC	5,44	1	0	probably_damaging	0,92	neutral	0,54	neutral	2,98	neutral	-0,95	neutral	-2,41	medium_impact	2,52	neutral	0,88	damaging	0,09	deleterious	3,24	22,8	0,18	0,45	disease	0,62	disease	0,63	neutral	0,38	neutral	0,37	3	neutral	0,91	neutral	0,31	deleterious	1	deleterious	0,76	low_impact	-1,72	medium_impact	0,26	medium_impact	1,1	0,38	0,8	31,58	10,28	N	0,39	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15682	15682	A	T	MI.10324	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	936	312	Q	H	caA/caT	5,44	1	0	probably_damaging	0,92	neutral	0,54	neutral	2,98	neutral	-0,95	neutral	-2,41	medium_impact	2,52	neutral	0,88	damaging	0,09	deleterious	3,44	23	0,18	0,45	disease	0,62	disease	0,63	neutral	0,38	neutral	0,37	3	neutral	0,91	neutral	0,31	deleterious	1	deleterious	0,76	low_impact	-1,72	medium_impact	0,26	medium_impact	1,1	0,38	0,8	31,58	10,28	N	0,4	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15683	15683	C	G	MI.10325	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	937	313	Q	E	Caa/Gaa	2,46	1	0	probably_damaging	0,98	neutral	0,54	neutral	3,01	neutral	0,11	neutral	-0,92	medium_impact	2,34	neutral	0,92	neutral	0,51	neutral	1,37	12,63	0,29	0,45	neutral	0,24	disease	0,61	disease	0,66	disease	0,7	4	neutral	0,97	neutral	0,28	deleterious	1	deleterious	0,72	low_impact	-2,31	medium_impact	0,26	medium_impact	0,93	0,39	0,8	24,21	42,13	N	0,36	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15683	15683	C	A	MI.10326	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	937	313	Q	K	Caa/Aaa	2,46	1	0	probably_damaging	0,99	neutral	0,55	neutral	3,07	neutral	0,65	neutral	-0,06	neutral_impact	0,34	neutral	0,93	neutral	0,47	deleterious	2,35	18,49	0,25	0,45	neutral	0,18	disease	0,67	neutral	0,45	neutral	0,41	2	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,7	low_impact	-2,59	medium_impact	0,27	medium_impact	-0,89	0,32	0,8	24,21	42,13	N	0,33	N	0,43	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15684	15684	A	G	MI.10327	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	938	313	Q	R	cAa/cGa	4,29	1	0	probably_damaging	0,99	neutral	0,51	neutral	3,1	neutral	0,9	neutral	1,4	neutral_impact	-1,88	neutral	0,96	neutral	0,91	neutral	-1,18	0,01	0,23	0,45	neutral	0,16	neutral	0,18	neutral	0,36	neutral	0,23	5	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,65	low_impact	-2,59	medium_impact	0,23	low_impact	-2,9	0,28	0,8	24,21	42,13	N	0,44	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15684	15684	A	C	MI.10328	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	938	313	Q	P	cAa/cCa	4,29	1	0	probably_damaging	0,99	neutral	0,28	neutral	2,91	neutral	-2,03	neutral	-2,33	medium_impact	2	neutral	0,91	neutral	0,35	neutral	1,63	14,01	0,04	0,35	disease	0,51	disease	0,84	disease	0,65	disease	0,78	6	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,85	low_impact	-2,59	medium_impact	0	medium_impact	0,62	0,16	0,8	24,21	42,13	N	0,43	N	0,97	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15684	15684	A	T	MI.10329	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	938	313	Q	L	cAa/cTa	4,29	1	0	probably_damaging	0,99	neutral	0,74	neutral	2,93	neutral	-1,16	neutral	-2,41	low_impact	1,22	neutral	0,96	neutral	0,54	deleterious	1,89	15,55	0,07	0,35	neutral	0,35	disease	0,63	disease	0,62	disease	0,69	4	deleterious	0,99	neutral	0,38	neutral	-2	deleterious	0,75	low_impact	-2,59	medium_impact	0,47	medium_impact	-0,09	0,11	0,8	24,21	42,13	N	0,39	N	0,86	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9013	9013	A	T	MI.1033	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	487	163	N	Y	Aac/Tac	-13,06	0	0	probably_damaging	1	deleterious	0	neutral	1,76	deleterious	-10,28	deleterious	-7,19	high_impact	4,63	damaging	0,52	damaging	0,05	deleterious	3,85	23,4	0,18	0,65	disease	0,99	disease	0,93	disease	0,8	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,38	0,9	49,56	8,85	N	0,38	N	1	disease_causing	0,88	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15685	15685	A	C	MI.10330	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	939	313	Q	H	caA/caC	2,92	1	0	probably_damaging	1	neutral	0,57	neutral	2,91	neutral	-1,8	neutral	-1,19	medium_impact	2,14	neutral	0,94	neutral	0,52	deleterious	3,13	22,6	0,2	0,45	neutral	0,47	neutral	0,47	disease	0,59	neutral	0,47	1	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,77	low_impact	-3,53	medium_impact	0,29	medium_impact	0,75	0,39	0,8	24,21	42,13	N	0,36	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15685	15685	A	T	MI.10331	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	939	313	Q	H	caA/caT	2,92	1	0	probably_damaging	1	neutral	0,57	neutral	2,91	neutral	-1,8	neutral	-1,19	medium_impact	2,14	neutral	0,94	neutral	0,52	deleterious	3,23	22,8	0,2	0,45	neutral	0,47	neutral	0,47	disease	0,59	neutral	0,47	1	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,77	low_impact	-3,53	medium_impact	0,29	medium_impact	0,75	0,39	0,8	24,21	42,13	N	0,37	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15686	15686	A	C	MI.10332	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	940	314	S	R	Agc/Cgc	-0,98	0	0	probably_damaging	1	neutral	0,37	neutral	2,93	neutral	-1,87	neutral	-2,17	high_impact	3,96	neutral	0,95	neutral	0,4	deleterious	3,81	23,4	0,04	0,35	neutral	0,44	disease	0,77	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,1	high_impact	2,4	0,43	0,8	48,16	12,57	N	0,38	N	1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15686	15686	A	G	MI.10333	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	940	314	S	G	Agc/Ggc	-0,98	0	0	probably_damaging	1	neutral	0,35	neutral	3	neutral	-1,13	neutral	-0,41	low_impact	1,14	neutral	0,96	neutral	0,82	neutral	1,78	14,88	0,14	0,4	neutral	0,27	neutral	0,14	neutral	0,38	neutral	0,25	5	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,65	low_impact	-3,53	medium_impact	0,08	medium_impact	-0,16	0,55	0,8	48,16	12,57	N	0,47	N	0,89	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15686	15686	A	T	MI.10334	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	940	314	S	C	Agc/Tgc	-0,98	0	0	probably_damaging	1	neutral	0,18	neutral	2,85	deleterious	-4,65	neutral	-2,3	high_impact	4,07	neutral	0,95	neutral	0,36	deleterious	3,39	23	0,06	0,35	disease	0,66	disease	0,65	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,73	low_impact	-3,53	medium_impact	-0,14	high_impact	2,5	0,3	0,8	48,16	12,57	N	0,45	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15687	15687	G	C	MI.10335	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	941	314	S	T	aGc/aCc	-0,06	0	0	probably_damaging	0,99	neutral	0,4	neutral	2,92	neutral	-2,08	neutral	-0,94	low_impact	1,32	neutral	0,97	neutral	0,68	deleterious	0,72	8,93	0,19	0,45	neutral	0,24	neutral	0,31	neutral	0,37	neutral	0,42	2	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,61	low_impact	-2,59	medium_impact	0,13	medium_impact	0,01	0,51	0,8	48,16	12,57	N	0,4	N	0,7	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15687	15687	G	A	MI.10336	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	941	314	S	N	aGc/aAc	-0,06	0	0	probably_damaging	0,99	neutral	0,32	neutral	2,97	neutral	-1,37	neutral	-1,17	medium_impact	2,69	neutral	0,91	neutral	0,49	deleterious	2,19	17,47	0,37	0,5	neutral	0,35	disease	0,53	disease	0,61	disease	0,56	1	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,69	low_impact	-2,59	medium_impact	0,05	medium_impact	1,25	0,35	0,8	48,16	12,57	N	0,37	N	0,93	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15687	15687	G	T	MI.10337	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	941	314	S	I	aGc/aTc	-0,06	0	0	probably_damaging	1	neutral	0,4	neutral	2,85	deleterious	-4,82	deleterious	-2,84	high_impact	4,07	neutral	0,95	neutral	0,46	deleterious	4,25	23,9	0,04	0,35	disease	0,59	disease	0,81	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,13	high_impact	2,5	0,44	0,8	48,16	12,57	N	0,39	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15689	15689	A	G	MI.10338	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	943	315	M	V	Ata/Gta	-1,21	0	0	probably_damaging	0,98	neutral	0,52	neutral	3,17	neutral	0,01	neutral	-1,32	medium_impact	1,97	neutral	0,85	damaging	0,19	neutral	1,1	11,23	0,28	0,45	neutral	0,31	disease	0,57	disease	0,63	disease	0,58	2	neutral	0,97	neutral	0,27	deleterious	1	deleterious	0,68	low_impact	-2,31	medium_impact	0,24	medium_impact	0,6	0,4	0,8	16,05	26	N	0,23	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15689	15689	A	C	MI.10339	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	943	315	M	L	Ata/Cta	-1,21	0	0	probably_damaging	0,96	neutral	0,71	neutral	3,27	neutral	0,96	neutral	-0,22	neutral_impact	-0,1	neutral	0,94	neutral	0,85	neutral	-0,66	0,09	0,24	0,45	neutral	0,24	neutral	0,18	neutral	0,33	neutral	0,24	5	neutral	0,95	neutral	0,38	neutral	-2	deleterious	0,59	low_impact	-2,02	medium_impact	0,43	low_impact	-1,28	0,36	0,8	16,05	26	N	0,27	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9013	9013	A	C	MI.1034	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	487	163	N	H	Aac/Cac	-13,06	0	0	probably_damaging	1	deleterious	0	neutral	1,76	deleterious	-10,16	deleterious	-4,49	high_impact	4,63	damaging	0,55	damaging	0,09	deleterious	3,15	22,6	0,18	0,65	disease	0,98	disease	0,89	disease	0,84	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,45	0,9	49,56	8,85	N	0,42	N	0,98	disease_causing	0,63	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15689	15689	A	T	MI.10340	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	943	315	M	L	Ata/Tta	-1,21	0	0	probably_damaging	0,96	neutral	0,71	neutral	3,27	neutral	0,96	neutral	-0,22	neutral_impact	-0,1	neutral	0,94	neutral	0,85	neutral	-0,57	0,15	0,24	0,45	neutral	0,24	neutral	0,18	neutral	0,33	neutral	0,24	5	neutral	0,95	neutral	0,38	neutral	-2	deleterious	0,59	low_impact	-2,02	medium_impact	0,43	low_impact	-1,28	0,36	0,8	16,05	26	N	0,28	N	0,07	polymorphism	1	0	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15690	15690	T	C	MI.10341	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	944	315	M	T	aTa/aCa	-1,21	0	0	probably_damaging	1	neutral	0,44	neutral	3,13	neutral	-0,6	neutral	-2,3	low_impact	1,64	neutral	0,85	damaging	0,17	deleterious	1,97	16,04	0,19	0,45	neutral	0,35	disease	0,53	neutral	0,49	neutral	0,24	5	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,71	low_impact	-3,53	medium_impact	0,17	medium_impact	0,3	0,11	0,8	16,05	26	N	0,26	N	0,85	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15690	15690	T	A	MI.10342	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	944	315	M	K	aTa/aAa	-1,21	0	0	probably_damaging	1	neutral	0,35	neutral	3,1	neutral	-1,32	deleterious	-2,71	medium_impact	3,01	neutral	0,85	damaging	0,12	deleterious	3,98	23,6	0,05	0,35	neutral	0,36	disease	0,75	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,75	low_impact	-3,53	medium_impact	0,08	medium_impact	1,54	0,13	0,8	16,05	26	N	0,27	N	0,96	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15691	15691	A	T	MI.10343	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	945	315	M	I	atA/atT	2,69	0,07	0	probably_damaging	0,98	neutral	0,43	neutral	3,17	neutral	0,01	neutral	-1,02	low_impact	1,84	neutral	0,9	damaging	0,17	deleterious	1,82	15,13	0,26	0,45	neutral	0,29	disease	0,6	neutral	0,45	neutral	0,22	6	deleterious	0,98	neutral	0,23	neutral	-2	deleterious	0,7	low_impact	-2,31	medium_impact	0,16	medium_impact	0,48	0,48	0,8	16,05	26	N	0,4	N	0,66	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15691	15691	A	C	MI.10344	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	945	315	M	I	atA/atC	2,69	0,07	0	probably_damaging	0,98	neutral	0,43	neutral	3,17	neutral	0,01	neutral	-1,02	low_impact	1,84	neutral	0,9	damaging	0,17	neutral	1,77	14,8	0,26	0,45	neutral	0,29	disease	0,6	neutral	0,45	neutral	0,22	6	deleterious	0,98	neutral	0,23	neutral	-2	deleterious	0,7	low_impact	-2,31	medium_impact	0,16	medium_impact	0,48	0,48	0,8	16,05	26	N	0,4	N	0,66	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15692	15692	A	T	MI.10345	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	946	316	M	L	Ata/Tta	-1,44	0	0	benign	0,03	neutral	0,81	neutral	3,06	neutral	1,47	neutral	-0,57	medium_impact	2,36	neutral	0,97	neutral	0,79	deleterious	0,49	7,34	0,27	0,45	neutral	0,23	disease	0,52	disease	0,64	disease	0,58	2	neutral	0,13	deleterious	0,89	neutral	-3	neutral	0,14	medium_impact	0,68	medium_impact	0,56	medium_impact	0,95	0,49	0,8	20,53	21,18	N	0,3	N	0,47	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15692	15692	A	G	MI.10346	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	946	316	M	V	Ata/Gta	-1,44	0	0	benign	0,05	neutral	0,58	neutral	3,04	neutral	0,73	neutral	-0,36	low_impact	1,94	neutral	0,96	neutral	0,73	neutral	-0,2	1,08	0,26	0,45	neutral	0,2	disease	0,55	disease	0,67	neutral	0,43	1	neutral	0,36	deleterious	0,77	neutral	-6	neutral	0,13	medium_impact	0,46	medium_impact	0,3	medium_impact	0,57	0,41	0,8	20,53	21,18	N	0,22	N	0,47	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15692	15692	A	C	MI.10347	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	946	316	M	L	Ata/Cta	-1,44	0	0	benign	0,03	neutral	0,81	neutral	3,06	neutral	1,47	neutral	-0,57	medium_impact	2,36	neutral	0,97	neutral	0,79	deleterious	0,42	6,77	0,27	0,45	neutral	0,23	disease	0,52	disease	0,64	disease	0,58	2	neutral	0,13	deleterious	0,89	neutral	-3	neutral	0,14	medium_impact	0,68	medium_impact	0,56	medium_impact	0,95	0,49	0,8	20,53	21,18	N	0,3	N	0,47	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15693	15693	T	A	MI.10348	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	947	316	M	K	aTa/aAa	0,63	0	0,02	benign	0,1	neutral	0,33	neutral	3,09	neutral	1,77	neutral	-0,89	low_impact	1,73	neutral	0,92	neutral	0,5	deleterious	2,41	18,87	0,06	0,35	neutral	0,44	disease	0,72	disease	0,69	disease	0,6	2	neutral	0,62	deleterious	0,62	neutral	-6	neutral	0,27	medium_impact	0,16	medium_impact	0,06	medium_impact	0,38	0,23	0,8	20,53	21,18	N	0,28	N	0,85	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15693	15693	T	C	MI.10349	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	947	316	M	T	aTa/aCa	0,63	0	0,02	benign	0,01	neutral	0,58	neutral	3,06	neutral	1,27	neutral	1,04	neutral_impact	-0,42	neutral	0,99	neutral	0,96	neutral	-1,09	0,01	0,14	0,4	neutral	0,23	neutral	0,18	disease	0,52	neutral	0,25	5	neutral	0,41	deleterious	0,79	neutral	-6	neutral	0,08	medium_impact	1,13	medium_impact	0,3	low_impact	-1,58	0,17	0,8	20,53	21,18	N	0,36	N	0,03	polymorphism	1	0	rs200975632	.	.	.	.	breast tumor	.	.	5,35	T15693C	Possibly LVNC cardiomyopathy-associated	+	-	Reported	1
chrM	9013	9013	A	G	MI.1035	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	487	163	N	D	Aac/Gac	-13,06	0	0	probably_damaging	0,99	deleterious	0	neutral	1,78	deleterious	-8,08	deleterious	-4,49	high_impact	4,63	damaging	0,56	damaging	0,06	deleterious	3,95	23,6	0,33	0,65	disease	0,93	disease	0,88	disease	0,82	disease	0,85	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,65	low_impact	-1,4	high_impact	2,87	0,43	0,9	49,56	8,85	N	0,44	N	0,97	polymorphism	0,55	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15694	15694	A	C	MI.10350	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	948	316	M	I	atA/atC	-0,06	0	0	benign	0,1	neutral	0,48	neutral	3,03	neutral	0,31	neutral	-0,76	low_impact	1,22	neutral	0,95	neutral	0,82	deleterious	0,25	5,16	0,23	0,45	neutral	0,28	disease	0,57	disease	0,66	neutral	0,42	2	neutral	0,45	deleterious	0,69	neutral	-6	neutral	0,19	medium_impact	0,16	medium_impact	0,2	medium_impact	-0,09	0,54	0,8	20,53	21,18	N	0,29	N	0,47	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15694	15694	A	T	MI.10351	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	948	316	M	I	atA/atT	-0,06	0	0	benign	0,1	neutral	0,48	neutral	3,03	neutral	0,31	neutral	-0,76	low_impact	1,22	neutral	0,95	neutral	0,82	deleterious	0,31	5,78	0,23	0,45	neutral	0,28	disease	0,57	disease	0,66	neutral	0,42	2	neutral	0,45	deleterious	0,69	neutral	-6	neutral	0,19	medium_impact	0,16	medium_impact	0,2	medium_impact	-0,09	0,54	0,8	20,53	21,18	N	0,3	N	0,47	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15695	15695	T	C	MI.10352	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	949	317	F	L	Ttt/Ctt	-3,5	0	0	probably_damaging	1	neutral	0,71	neutral	2,9	neutral	-0,82	deleterious	-3,71	medium_impact	3,21	neutral	0,92	damaging	0,1	deleterious	3,86	23,5	0,16	0,45	neutral	0,45	disease	0,67	disease	0,68	disease	0,55	1	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,76	low_impact	-3,53	medium_impact	0,43	medium_impact	1,72	0,73	0,85	53,95	8,67	N	0,23	N	0,92	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15695	15695	T	A	MI.10353	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	949	317	F	I	Ttt/Att	-3,5	0	0	probably_damaging	1	neutral	0,48	neutral	2,85	neutral	-1,41	deleterious	-3,72	high_impact	5	neutral	0,87	damaging	0,12	deleterious	4,36	24,1	0,11	0,4	disease	0,63	disease	0,82	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,2	high_impact	3,35	0,36	0,8	53,95	8,67	P	0,64	P	0,97	polymorphism	1	0,09	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15695	15695	T	G	MI.10354	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	949	317	F	V	Ttt/Gtt	-3,5	0	0	probably_damaging	1	neutral	0,54	neutral	2,88	neutral	-1,06	deleterious	-4,34	high_impact	4,46	neutral	0,88	damaging	0,11	deleterious	4,06	23,7	0,06	0,35	disease	0,6	disease	0,81	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,26	high_impact	2,86	0,25	0,8	53,95	8,67	N	0,37	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15696	15696	T	C	MI.10355	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	950	317	F	S	tTt/tCt	4,52	1	0	probably_damaging	1	neutral	0,45	neutral	2,83	neutral	-1,91	deleterious	-4,99	high_impact	3,56	neutral	0,86	damaging	0,08	deleterious	4,42	24,2	0,03	0,35	disease	0,7	disease	0,79	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,18	high_impact	2,04	0,16	0,8	53,95	8,67	N	0,42	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15696	15696	T	G	MI.10356	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	950	317	F	C	tTt/tGt	4,52	1	0	probably_damaging	1	neutral	0,17	neutral	2,78	deleterious	-3,71	deleterious	-4,99	high_impact	4,46	neutral	0,87	damaging	0,09	deleterious	4,28	24	0,04	0,35	disease	0,88	disease	0,81	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,15	high_impact	2,86	0,19	0,8	53,95	8,67	P	0,54	P	0,99	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15696	15696	T	A	MI.10357	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	950	317	F	Y	tTt/tAt	4,52	1	0	probably_damaging	1	neutral	1	neutral	3,01	neutral	0,04	neutral	-1,78	low_impact	1,54	neutral	0,88	damaging	0,11	deleterious	4,16	23,8	0,12	0,4	disease	0,62	disease	0,64	neutral	0,45	neutral	0,22	6	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,79	low_impact	-3,53	high_impact	1,85	medium_impact	0,21	0,62	0,8	53,95	8,67	N	0,36	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15697	15697	T	G	MI.10358	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	951	317	F	L	ttT/ttG	7,27	1	0,01	probably_damaging	1	neutral	0,71	neutral	2,9	neutral	-0,82	deleterious	-3,71	medium_impact	3,21	neutral	0,92	damaging	0,1	deleterious	4,22	23,9	0,16	0,45	neutral	0,45	disease	0,67	disease	0,68	disease	0,55	1	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,76	low_impact	-3,53	medium_impact	0,43	medium_impact	1,72	0,73	0,85	53,95	8,67	N	0,52	P	0,92	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15697	15697	T	A	MI.10359	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	951	317	F	L	ttT/ttA	7,27	1	0,01	probably_damaging	1	neutral	0,71	neutral	2,9	neutral	-0,82	deleterious	-3,71	medium_impact	3,21	neutral	0,92	damaging	0,1	deleterious	4,3	24	0,16	0,45	neutral	0,45	disease	0,67	disease	0,68	disease	0,55	1	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,76	low_impact	-3,53	medium_impact	0,43	medium_impact	1,72	0,73	0,85	53,95	8,67	N	0,53	P	0,92	polymorphism	1	0,04	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	9014	9014	A	T	MI.1036	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	488	163	N	I	aAc/aTc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	1,76	deleterious	-10,49	deleterious	-8,09	high_impact	4,63	damaging	0,52	damaging	0,06	deleterious	3,99	23,6	0,18	0,65	disease	0,98	disease	0,95	disease	0,77	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,35	0,9	49,56	8,85	P	0,48	N	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15698	15698	C	T	MI.10360	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	952	318	R	C	Cgc/Tgc	-0,52	0,1	0	probably_damaging	1	neutral	0,17	neutral	2,85	deleterious	-6,08	deleterious	-4,87	high_impact	4,52	neutral	0,86	damaging	0,04	deleterious	5,07	25,3	0,08	0,35	disease	0,91	disease	0,79	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,15	high_impact	2,91	0,81	0,85	57,63	8,5	N	0,46	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15698	15698	C	G	MI.10361	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	952	318	R	G	Cgc/Ggc	-0,52	0,1	0	probably_damaging	1	neutral	0,36	neutral	2,88	deleterious	-3,99	deleterious	-4,29	high_impact	4,72	neutral	0,84	damaging	0,11	deleterious	4,04	23,7	0,05	0,35	disease	0,76	disease	0,66	disease	0,78	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,09	high_impact	3,09	0,31	0,8	57,63	8,5	P	0,69	P	0,99	polymorphism	1	0,13	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15698	15698	C	A	MI.10362	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	952	318	R	S	Cgc/Agc	-0,52	0,1	0	probably_damaging	1	neutral	0,41	neutral	2,92	neutral	-2,66	deleterious	-3,65	medium_impact	3,08	neutral	0,8	damaging	0,06	deleterious	4,48	24,2	0,06	0,35	disease	0,63	disease	0,73	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,8	low_impact	-3,53	medium_impact	0,14	medium_impact	1,6	0,35	0,8	57,63	8,5	N	0,26	N	0,74	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15699	15699	G	T	MI.10363	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	953	318	R	L	cGc/cTc	2,69	0,97	0	probably_damaging	1	neutral	0,77	neutral	2,94	deleterious	-3,73	deleterious	-4,25	high_impact	4,72	neutral	0,87	damaging	0,06	deleterious	2,89	21,8	0,06	0,35	disease	0,69	disease	0,83	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,51	high_impact	3,09	0,17	0,8	57,63	8,5	P	0,62	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15699	15699	G	C	MI.10364	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	953	318	R	P	cGc/cCc	2,69	0,97	0	probably_damaging	1	neutral	0,25	neutral	2,87	deleterious	-4,52	deleterious	-4,29	high_impact	3,87	neutral	0,86	damaging	0,04	deleterious	4,22	23,9	0,03	0,35	disease	0,81	disease	0,82	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,04	high_impact	2,32	0,2	0,8	57,63	8,5	P	0,69	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	G15699C	Muscle Weakness SNHL and Migraine	-	+	Reported	2
chrM	15699	15699	G	A	MI.10365	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	953	318	R	H	cGc/cAc	2,69	0,97	0	probably_damaging	1	neutral	0,47	neutral	2,89	deleterious	-3,69	deleterious	-2,96	high_impact	4,38	neutral	0,82	damaging	0,06	deleterious	4,46	24,2	0,14	0,4	disease	0,76	disease	0,73	neutral	0,5	neutral	0,49	0	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,19	high_impact	2,78	0,81	0,85	57,63	8,5	N	0,43	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15701	15701	C	A	MI.10366	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	955	319	P	T	Cca/Aca	-6,02	0	0	probably_damaging	1	neutral	0,4	neutral	2,82	neutral	-2,79	deleterious	-5,04	high_impact	4,16	neutral	0,82	damaging	0,08	deleterious	3,73	23,3	0,06	0,35	neutral	0,47	disease	0,72	disease	0,7	disease	0,66	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,75	low_impact	-3,53	medium_impact	0,13	high_impact	2,58	0,56	0,8	58,42	8,63	N	0,29	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15701	15701	C	T	MI.10367	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	955	319	P	S	Cca/Tca	-6,02	0	0	probably_damaging	1	neutral	0,4	neutral	2,8	deleterious	-3,05	deleterious	-5,04	high_impact	3,81	neutral	0,84	damaging	0,07	deleterious	3,98	23,6	0,06	0,35	neutral	0,43	disease	0,71	disease	0,7	disease	0,65	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,13	high_impact	2,27	0,18	0,8	58,42	8,63	N	0,27	N	0,9	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15701	15701	C	G	MI.10368	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	955	319	P	A	Cca/Gca	-6,02	0	0	probably_damaging	1	neutral	0,5	neutral	2,82	neutral	-2,64	deleterious	-5,04	high_impact	4,3	neutral	0,87	damaging	0,11	deleterious	2,9	21,8	0,07	0,35	neutral	0,41	disease	0,58	disease	0,72	disease	0,66	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,73	low_impact	-3,53	medium_impact	0,22	high_impact	2,71	0,64	0,8	58,42	8,63	N	0,37	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15702	15702	C	A	MI.10369	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	956	319	P	Q	cCa/cAa	5,44	1	0	probably_damaging	1	neutral	0,3	neutral	2,78	deleterious	-3,68	deleterious	-5,05	high_impact	4,85	neutral	0,85	damaging	0,05	deleterious	4,14	23,8	0,05	0,35	neutral	0,46	disease	0,79	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,02	high_impact	3,21	0,31	0,8	58,42	8,63	P	0,66	P	0,86	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9014	9014	A	C	MI.1037	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	488	163	N	T	aAc/aCc	8,69	1	0	probably_damaging	0,99	deleterious	0,04	neutral	1,77	deleterious	-8,96	deleterious	-5,35	high_impact	4,63	damaging	0,53	damaging	0,06	deleterious	3,49	23,1	0,21	0,65	disease	0,84	disease	0,88	disease	0,77	disease	0,81	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,87	low_impact	-2,65	medium_impact	-0,49	high_impact	2,87	0,45	0,9	49,56	8,85	P	0,51	P	0,96	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15702	15702	C	G	MI.10370	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	956	319	P	R	cCa/cGa	5,44	1	0	probably_damaging	1	neutral	0,38	neutral	2,81	neutral	-2,98	deleterious	-5,68	high_impact	4,85	neutral	0,82	damaging	0,05	deleterious	3,67	23,2	0,02	0,35	neutral	0,47	disease	0,82	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	0,11	high_impact	3,21	0,27	0,8	58,42	8,63	P	0,68	P	0,8	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15702	15702	C	T	MI.10371	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	956	319	P	L	cCa/cTa	5,44	1	0	probably_damaging	1	neutral	0,66	neutral	2,88	neutral	-1,82	deleterious	-6,31	medium_impact	3,44	neutral	0,85	damaging	0,05	deleterious	4,47	24,2	0,04	0,35	neutral	0,49	disease	0,78	disease	0,67	disease	0,65	3	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,76	low_impact	-3,53	medium_impact	0,38	medium_impact	1,93	0,53	0,8	58,42	8,63	N	0,38	N	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15704	15704	C	G	MI.10372	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	958	320	L	V	Cta/Gta	-14,04	0	0	probably_damaging	0,98	neutral	0,5	neutral	2,92	neutral	-0,52	neutral	-0,86	low_impact	1,64	neutral	0,97	neutral	0,73	deleterious	0,79	9,38	0,31	0,45	neutral	0,35	neutral	0,43	neutral	0,33	neutral	0,47	1	neutral	0,98	neutral	0,26	neutral	-2	deleterious	0,66	low_impact	-2,31	medium_impact	0,22	medium_impact	0,3	0,65	0,8	10	16,86	N	0,36	N	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15704	15704	C	A	MI.10373	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	958	320	L	M	Cta/Ata	-14,04	0	0	probably_damaging	1	neutral	0,22	neutral	2,89	neutral	-2,02	neutral	-0,65	low_impact	1,17	neutral	0,93	neutral	0,76	deleterious	2,58	20,1	0,33	0,5	disease	0,58	neutral	0,33	neutral	0,29	disease	0,6	2	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,7	low_impact	-3,53	medium_impact	-0,08	medium_impact	-0,13	0,59	0,8	10	16,86	N	0,47	N	0,49	polymorphism	1	0,01	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15705	15705	T	A	MI.10374	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	959	320	L	Q	cTa/cAa	-9,69	0	0	probably_damaging	1	neutral	0,29	neutral	2,8	deleterious	-3,3	deleterious	-3,04	high_impact	3,52	neutral	0,94	neutral	0,52	deleterious	4,24	23,9	0,02	0,35	disease	0,73	disease	0,71	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,01	high_impact	2	0,24	0,8	10	16,86	N	0,37	N	0,91	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15705	15705	T	G	MI.10375	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	959	320	L	R	cTa/cGa	-9,69	0	0	probably_damaging	1	neutral	0,35	neutral	2,8	deleterious	-3,13	deleterious	-3,13	high_impact	4,32	neutral	0,94	neutral	0,47	deleterious	4,22	23,9	0,01	0,35	disease	0,71	disease	0,85	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,08	high_impact	2,73	0,16	0,8	10	16,86	N	0,51	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15705	15705	T	C	MI.10376	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	959	320	L	P	cTa/cCa	-9,69	0	0	probably_damaging	1	neutral	0,21	neutral	2,79	deleterious	-3,82	deleterious	-3,51	medium_impact	3,08	neutral	0,93	neutral	0,35	deleterious	4,02	23,6	0,01	0,35	disease	0,79	disease	0,85	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,87	low_impact	-3,53	medium_impact	-0,09	medium_impact	1,6	0,18	0,8	10	16,86	N	0,38	N	0,94	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15707	15707	A	G	MI.10377	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	961	321	S	G	Agc/Ggc	-20	0	0	probably_damaging	1	neutral	0,36	neutral	2,94	neutral	-1,85	neutral	-2,15	medium_impact	2,45	neutral	0,97	neutral	0,52	deleterious	3,4	23	0,12	0,4	neutral	0,46	disease	0,6	neutral	0,34	neutral	0,32	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,72	low_impact	-3,53	medium_impact	0,09	medium_impact	1,03	0,62	0,8	17,63	26,07	N	0,34	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15707	15707	A	T	MI.10378	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	961	321	S	C	Agc/Tgc	-20	0	0	probably_damaging	1	neutral	0,17	neutral	2,92	deleterious	-3,11	neutral	-2,33	medium_impact	3,35	neutral	0,95	neutral	0,35	deleterious	3,53	23,1	0,06	0,35	disease	0,78	disease	0,79	disease	0,52	disease	0,64	3	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,78	low_impact	-3,53	medium_impact	-0,15	medium_impact	1,85	0,36	0,8	17,63	26,07	N	0,36	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15707	15707	A	C	MI.10379	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	961	321	S	R	Agc/Cgc	-20	0	0	probably_damaging	1	neutral	0,36	neutral	2,93	neutral	-1,56	neutral	-2,26	high_impact	3,64	neutral	0,95	neutral	0,4	deleterious	3,95	23,6	0,03	0,35	neutral	0,46	disease	0,87	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,09	high_impact	2,11	0,47	0,8	17,63	26,07	N	0,41	N	0,95	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9014	9014	A	G	MI.1038	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	488	163	N	S	aAc/aGc	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	1,78	deleterious	-8,41	deleterious	-4,45	high_impact	4,63	damaging	0,5	damaging	0,06	deleterious	3,2	22,7	0,29	0,65	disease	0,92	disease	0,88	disease	0,76	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,65	low_impact	-1,4	high_impact	2,87	0,37	0,9	49,56	8,85	P	0,52	P	0,91	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15708	15708	G	T	MI.10380	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	962	321	S	I	aGc/aTc	1,54	0,77	0	probably_damaging	1	neutral	0,58	neutral	3,01	neutral	-0,81	deleterious	-2,68	medium_impact	3,35	neutral	0,95	neutral	0,44	deleterious	4,22	23,9	0,03	0,35	neutral	0,49	disease	0,89	disease	0,62	disease	0,69	4	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,79	low_impact	-3,53	medium_impact	0,3	medium_impact	1,85	0,37	0,8	17,63	26,07	N	0,25	N	0,96	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15708	15708	G	A	MI.10381	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	962	321	S	N	aGc/aAc	1,54	0,77	0	probably_damaging	0,99	neutral	0,33	neutral	2,94	neutral	-1,71	neutral	-1,2	low_impact	1,5	neutral	0,94	neutral	0,47	deleterious	2,2	17,54	0,35	0,5	neutral	0,36	disease	0,69	neutral	0,26	neutral	0,19	6	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,72	low_impact	-2,59	medium_impact	0,06	medium_impact	0,17	0,49	0,8	17,63	26,07	N	0,33	N	0,59	polymorphism	1	0,01	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15708	15708	G	C	MI.10382	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	962	321	S	T	aGc/aCc	1,54	0,77	0	probably_damaging	0,99	neutral	0,55	neutral	2,98	neutral	-0,95	neutral	-0,07	neutral_impact	0,78	neutral	0,98	neutral	0,93	deleterious	0,21	4,82	0,2	0,45	neutral	0,3	neutral	0,17	neutral	0,29	neutral	0,26	5	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,65	low_impact	-2,59	medium_impact	0,27	medium_impact	-0,49	0,62	0,8	17,63	26,07	N	0,33	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15710	15710	C	A	MI.10383	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	964	322	Q	K	Caa/Aaa	-6,71	0	0	benign	0,41	neutral	0,29	neutral	3,14	neutral	1,03	neutral	-2,43	low_impact	1,27	neutral	0,9	damaging	0,11	deleterious	2,33	18,35	0,18	0,45	neutral	0,2	disease	0,73	neutral	0,37	neutral	0,18	6	neutral	0,66	neutral	0,44	neutral	-6	deleterious	0,52	medium_impact	-0,58	medium_impact	0,01	medium_impact	-0,04	0,4	0,8	58,42	8,35	N	0,29	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15710	15710	C	G	MI.10384	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	964	322	Q	E	Caa/Gaa	-6,71	0	0	benign	0,3	neutral	0,28	neutral	2,98	neutral	-0,21	neutral	-1,85	high_impact	4,07	neutral	0,83	damaging	0,12	neutral	1,51	13,38	0,33	0,5	neutral	0,29	disease	0,66	disease	0,68	disease	0,65	3	neutral	0,66	deleterious	0,49	neutral	-2	neutral	0,4	medium_impact	-0,39	medium_impact	0	high_impact	2,5	0,39	0,8	58,42	8,35	N	0,35	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15711	15711	A	G	MI.10385	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	965	322	Q	R	cAa/cGa	5,44	1	0	possibly_damaging	0,52	neutral	0,35	neutral	2,97	neutral	-0,37	neutral	-2,45	medium_impact	2,42	neutral	0,91	damaging	0,11	deleterious	3,19	22,7	0,17	0,45	neutral	0,4	disease	0,8	neutral	0,5	neutral	0,39	2	neutral	0,63	neutral	0,42	NA	0	deleterious	0,58	medium_impact	-0,76	medium_impact	0,08	medium_impact	1	0,15	0,8	58,42	8,35	N	0,45	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15711	15711	A	T	MI.10386	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	965	322	Q	L	cAa/cTa	5,44	1	0	possibly_damaging	0,61	neutral	0,65	neutral	2,91	neutral	-1,27	deleterious	-4,35	medium_impact	3,33	neutral	0,86	damaging	0,09	deleterious	2,35	18,48	0,05	0,35	disease	0,54	disease	0,84	disease	0,64	disease	0,67	3	neutral	0,54	deleterious	0,52	NA	0	deleterious	0,64	medium_impact	-0,91	medium_impact	0,37	medium_impact	1,83	0,11	0,8	58,42	8,35	N	0,42	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15711	15711	A	C	MI.10387	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	965	322	Q	P	cAa/cCa	5,44	1	0	probably_damaging	0,92	neutral	0,21	neutral	2,89	neutral	-2,15	deleterious	-3,73	high_impact	4,18	neutral	0,83	damaging	0,07	deleterious	3,33	22,9	0,03	0,35	disease	0,64	disease	0,84	disease	0,78	disease	0,69	4	neutral	0,95	neutral	0,15	deleterious	2	deleterious	0,79	low_impact	-1,72	medium_impact	-0,09	high_impact	2,6	0,2	0,8	58,42	8,35	P	0,56	P	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15712	15712	A	C	MI.10388	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	966	322	Q	H	caA/caC	8,42	1	0	benign	0,03	neutral	0,54	neutral	2,89	neutral	-2,11	deleterious	-3,1	high_impact	4,53	neutral	0,8	damaging	0,12	deleterious	3,4	23	0,18	0,45	disease	0,6	disease	0,75	disease	0,7	disease	0,68	4	neutral	0,42	deleterious	0,76	neutral	-2	neutral	0,27	medium_impact	0,68	medium_impact	0,26	high_impact	2,92	0,51	0,8	58,42	8,35	N	0,51	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15712	15712	A	T	MI.10389	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	966	322	Q	H	caA/caT	8,42	1	0	benign	0,03	neutral	0,54	neutral	2,89	neutral	-2,11	deleterious	-3,1	high_impact	4,53	neutral	0,8	damaging	0,12	deleterious	3,56	23,1	0,18	0,45	disease	0,6	disease	0,75	disease	0,7	disease	0,68	4	neutral	0,42	deleterious	0,76	neutral	-2	neutral	0,27	medium_impact	0,68	medium_impact	0,26	high_impact	2,92	0,51	0,8	58,42	8,35	N	0,51	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9015	9015	C	A	MI.1039	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	489	163	N	K	aaC/aaA	7,07	1	0	probably_damaging	0,99	deleterious	0	neutral	1,77	deleterious	-8,84	deleterious	-5,39	high_impact	4,63	damaging	0,53	damaging	0,05	deleterious	4,58	24,4	0,24	0,65	disease	0,96	disease	0,93	disease	0,82	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-2,65	low_impact	-1,4	high_impact	2,87	0,58	0,9	49,56	8,85	P	0,52	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15713	15713	T	A	MI.10390	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	967	323	S	T	Tca/Aca	1,54	0,78	0	benign	0,15	neutral	0,39	neutral	3,02	neutral	0,4	neutral	0,31	neutral_impact	-0,99	neutral	0,96	neutral	0,96	deleterious	0,61	8,22	0,32	0,5	neutral	0,21	neutral	0,13	neutral	0,25	neutral	0,28	4	neutral	0,54	deleterious	0,62	neutral	-6	neutral	0,1	medium_impact	-0,03	medium_impact	0,12	low_impact	-2,09	0,7	0,85	29,21	40,21	N	0,38	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15713	15713	T	C	MI.10391	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	967	323	S	P	Tca/Cca	1,54	0,78	0	possibly_damaging	0,45	neutral	0,2	neutral	2,95	neutral	-1,6	neutral	-1,04	low_impact	0,83	neutral	0,84	neutral	0,44	deleterious	3,82	23,4	0,08	0,35	neutral	0,33	disease	0,77	disease	0,53	disease	0,6	2	neutral	0,77	neutral	0,38	neutral	-3	neutral	0,37	medium_impact	-0,65	medium_impact	-0,1	medium_impact	-0,44	0,45	0,8	29,21	40,21	N	0,28	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15713	15713	T	G	MI.10392	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	967	323	S	A	Tca/Gca	1,54	0,78	0	benign	0,05	neutral	0,51	neutral	3,08	neutral	1,15	neutral	0,25	neutral_impact	-0,52	neutral	0,87	neutral	0,83	neutral	0,89	10,04	0,32	0,5	neutral	0,21	neutral	0,22	neutral	0,37	neutral	0,35	3	neutral	0,44	deleterious	0,73	neutral	-6	neutral	0,11	medium_impact	0,46	medium_impact	0,23	low_impact	-1,67	0,6	0,8	29,21	40,21	N	0,32	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15714	15714	C	G	MI.10393	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	968	323	S	W	tCa/tGa	-1,44	0	0	possibly_damaging	0,76	neutral	0,18	neutral	2,98	neutral	-0,41	neutral	-0,21	neutral_impact	0,72	neutral	0,85	neutral	0,48	deleterious	4,31	24	0,06	0,35	neutral	0,37	disease	0,71	neutral	0,38	neutral	0,4	2	neutral	0,87	neutral	0,21	neutral	-3	deleterious	0,47	low_impact	-1,2	medium_impact	-0,14	medium_impact	-0,54	0,17	0,8	29,21	40,21	N	0,32	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15714	15714	C	T	MI.10394	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	968	323	S	L	tCa/tTa	-1,44	0	0	benign	0	neutral	0,65	neutral	3,14	neutral	1,64	neutral	1,31	neutral_impact	-1,58	neutral	0,96	neutral	0,85	deleterious	2,84	21,6	0,09	0,35	neutral	0,16	neutral	0,31	neutral	0,26	neutral	0,43	1	neutral	0,35	deleterious	0,83	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,37	low_impact	-2,63	0,52	0,8	29,21	40,21	N	0,31	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15716	15716	C	G	MI.10395	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	970	324	L	V	Ctt/Gtt	-5,33	0	0	benign	0,08	neutral	0,46	neutral	2,91	neutral	-0,64	neutral	-1,35	medium_impact	2,29	neutral	0,98	neutral	0,78	deleterious	3,18	22,7	0,31	0,45	neutral	0,46	neutral	0,45	neutral	0,42	neutral	0,42	2	neutral	0,48	deleterious	0,69	neutral	-3	neutral	0,19	medium_impact	0,26	medium_impact	0,18	medium_impact	0,89	0,61	0,8	42,63	9,99	N	0,33	N	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15716	15716	C	A	MI.10396	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	970	324	L	I	Ctt/Att	-5,33	0	0	benign	0,28	neutral	0,5	neutral	2,88	neutral	-0,55	neutral	-0,92	medium_impact	2,07	neutral	0,95	neutral	0,74	deleterious	2,98	22,2	0,35	0,5	neutral	0,39	disease	0,51	neutral	0,39	neutral	0,19	6	neutral	0,4	deleterious	0,61	neutral	-3	neutral	0,23	medium_impact	-0,35	medium_impact	0,22	medium_impact	0,69	0,65	0,8	42,63	9,99	N	0,32	N	0,51	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15716	15716	C	T	MI.10397	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	970	324	L	F	Ctt/Ttt	-5,33	0	0	possibly_damaging	0,52	neutral	0,67	neutral	2,85	neutral	-1,26	neutral	-1,99	low_impact	1,75	neutral	0,97	neutral	0,54	deleterious	3,98	23,6	0,18	0,45	neutral	0,47	disease	0,55	neutral	0,43	neutral	0,17	7	neutral	0,44	deleterious	0,58	neutral	-3	deleterious	0,46	medium_impact	-0,76	medium_impact	0,39	medium_impact	0,4	0,66	0,8	42,63	9,99	N	0,22	N	0,92	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15717	15717	T	A	MI.10398	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	971	324	L	H	cTt/cAt	-4,19	0	0	probably_damaging	0,93	neutral	0,23	neutral	2,77	deleterious	-3,77	deleterious	-3,66	high_impact	4,72	neutral	0,93	neutral	0,41	deleterious	4,41	24,1	0,04	0,35	disease	0,91	disease	0,76	disease	0,69	disease	0,66	3	neutral	0,95	neutral	0,15	deleterious	2	deleterious	0,78	low_impact	-1,78	medium_impact	-0,06	high_impact	3,09	0,29	0,8	42,63	9,99	P	0,66	P	0,89	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15717	15717	T	G	MI.10399	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	971	324	L	R	cTt/cGt	-4,19	0	0	possibly_damaging	0,68	neutral	0,18	neutral	2,79	deleterious	-3,06	deleterious	-3,1	high_impact	4,72	neutral	0,94	neutral	0,39	deleterious	4,24	23,9	0,01	0,35	disease	0,88	disease	0,86	disease	0,72	disease	0,64	3	neutral	0,85	neutral	0,25	deleterious	1	deleterious	0,66	low_impact	-1,04	medium_impact	-0,14	high_impact	3,09	0,23	0,8	42,63	9,99	P	0,69	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8573	8573	G	T	MI.104	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	47	16	G	V	gGc/gTc	6,14	1	0	probably_damaging	0,93	neutral	0,08	neutral	4,63	neutral	-0,22	deleterious	-7,22	high_impact	3,67	neutral	0,75	neutral	0,29	deleterious	3,47	23	0,22	0,65	neutral	0,43	disease	0,91	disease	0,68	disease	0,76	5	neutral	0,98	neutral	0,08	deleterious	2	deleterious	0,77	low_impact	-1,82	medium_impact	-0,31	high_impact	2,05	0,71	0,9	17,26	11,64	P	0,54	P	0,97	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9015	9015	C	G	MI.1040	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	489	163	N	K	aaC/aaG	7,07	1	0	probably_damaging	0,99	deleterious	0	neutral	1,77	deleterious	-8,84	deleterious	-5,39	high_impact	4,63	damaging	0,53	damaging	0,05	deleterious	4,05	23,7	0,24	0,65	disease	0,96	disease	0,93	disease	0,82	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-2,65	low_impact	-1,4	high_impact	2,87	0,58	0,9	49,56	8,85	P	0,52	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15717	15717	T	C	MI.10400	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	971	324	L	P	cTt/cCt	-4,19	0	0	possibly_damaging	0,83	neutral	0,18	neutral	2,77	deleterious	-3,84	deleterious	-3,65	high_impact	4,38	neutral	0,93	neutral	0,32	deleterious	4,03	23,6	0,01	0,35	disease	0,91	disease	0,81	disease	0,72	disease	0,64	3	neutral	0,91	neutral	0,18	deleterious	1	deleterious	0,77	low_impact	-1,37	medium_impact	-0,14	high_impact	2,78	0,34	0,8	42,63	9,99	N	0,5	N	0,92	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15719	15719	T	C	MI.10401	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	973	325	Y	H	Tat/Cat	-0,29	0,36	0	benign	0,03	neutral	0,32	neutral	3,11	neutral	-1,62	neutral	-2,49	medium_impact	3,21	neutral	0,89	neutral	0,49	deleterious	1,98	16,11	0,14	0,4	disease	0,61	disease	0,63	disease	0,72	disease	0,72	4	neutral	0,66	deleterious	0,65	neutral	-3	neutral	0,24	medium_impact	0,68	medium_impact	0,05	medium_impact	1,72	0,31	0,8	22,37	28,64	N	0,31	N	0,7	polymorphism	1	0,05	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15719	15719	T	G	MI.10402	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	973	325	Y	D	Tat/Gat	-0,29	0,36	0	possibly_damaging	0,73	neutral	0,12	neutral	3,11	neutral	-1,81	deleterious	-3,91	medium_impact	3,21	neutral	0,9	neutral	0,4	deleterious	2,39	18,78	0,03	0,35	disease	0,67	disease	0,85	disease	0,72	disease	0,75	5	neutral	0,91	neutral	0,2	NA	0	deleterious	0,76	low_impact	-1,13	medium_impact	-0,25	medium_impact	1,72	0,23	0,8	22,37	28,64	N	0,39	N	0,86	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15719	15719	T	A	MI.10403	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	973	325	Y	N	Tat/Aat	-0,29	0,36	0	possibly_damaging	0,66	neutral	0,42	neutral	3,13	neutral	-0,93	deleterious	-3,82	medium_impact	1,97	neutral	0,92	neutral	0,59	deleterious	2,47	19,27	0,05	0,35	disease	0,56	disease	0,83	disease	0,62	disease	0,75	5	neutral	0,67	neutral	0,38	NA	0	deleterious	0,61	medium_impact	-1	medium_impact	0,15	medium_impact	0,6	0,28	0,8	22,37	28,64	N	0,29	N	0,71	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15720	15720	A	G	MI.10404	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	974	325	Y	C	tAt/tGt	4,52	1	0	probably_damaging	0,96	neutral	0,11	neutral	3,1	neutral	-2,36	deleterious	-3,26	medium_impact	3,21	neutral	0,95	neutral	0,4	deleterious	2,04	16,44	0,04	0,35	disease	0,6	disease	0,79	disease	0,67	disease	0,74	5	deleterious	0,98	neutral	0,08	deleterious	1	deleterious	0,76	low_impact	-2,02	medium_impact	-0,27	medium_impact	1,72	0,21	0,8	22,37	28,64	N	0,45	N	0,67	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15720	15720	A	C	MI.10405	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	974	325	Y	S	tAt/tCt	4,52	1	0	possibly_damaging	0,73	neutral	0,34	neutral	3,14	neutral	-0,58	deleterious	-3,27	low_impact	1,76	neutral	0,92	neutral	0,54	deleterious	2,2	17,49	0,05	0,35	neutral	0,38	disease	0,68	disease	0,62	disease	0,7	4	neutral	0,77	neutral	0,31	neutral	-3	deleterious	0,61	low_impact	-1,13	medium_impact	0,07	medium_impact	0,41	0,24	0,8	22,37	28,64	N	0,49	N	0,72	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15720	15720	A	T	MI.10406	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	974	325	Y	F	tAt/tTt	4,52	1	0	possibly_damaging	0,57	neutral	1	neutral	3,45	neutral	2,21	neutral	1,31	neutral_impact	-1,86	neutral	0,96	neutral	0,95	neutral	-0,88	0,03	0,22	0,45	neutral	0,22	neutral	0,13	neutral	0,4	neutral	0,22	6	neutral	0,57	deleterious	0,72	neutral	-3	deleterious	0,49	medium_impact	-0,85	high_impact	1,85	low_impact	-2,88	0,49	0,8	22,37	28,64	N	0,46	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15722	15722	T	C	MI.10407	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	976	326	W	R	Tga/Cga	-0,29	0,7	0	probably_damaging	1	neutral	0,13	neutral	2,94	neutral	-2,62	deleterious	-8,62	high_impact	4,59	neutral	0,81	damaging	0,07	deleterious	2,06	16,6	0,03	0,35	disease	0,75	disease	0,89	disease	0,82	disease	0,76	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,23	high_impact	2,97	0,14	0,8	57,89	8,47	N	0,52	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15722	15722	T	G	MI.10408	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	976	326	W	G	Tga/Gga	-0,29	0,7	0	probably_damaging	1	neutral	0,2	neutral	2,96	neutral	-2,17	deleterious	-8	high_impact	3,62	neutral	0,75	damaging	0,13	deleterious	2,35	18,49	0,04	0,35	disease	0,73	disease	0,81	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	-0,1	high_impact	2,09	0,15	0,8	57,89	8,47	N	0,37	N	1	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15723	15723	G	C	MI.10409	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	977	326	W	S	tGa/tCa	5,67	1	0	probably_damaging	1	neutral	0,32	neutral	2,95	neutral	-2,27	deleterious	-8,62	high_impact	4,11	neutral	0,74	damaging	0,1	deleterious	2,44	19,11	0,04	0,35	disease	0,63	disease	0,86	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,05	high_impact	2,54	0,13	0,8	57,89	8,47	P	0,57	P	0,99	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9016	9016	A	T	MI.1041	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	490	164	I	F	Att/Ttt	-3,34	0	0	probably_damaging	0,99	deleterious	0	neutral	3,5	deleterious	-3,76	deleterious	-2,96	medium_impact	3	neutral	0,83	neutral	0,43	deleterious	3,59	23,2	0,26	0,65	disease	0,62	disease	0,74	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-2,65	low_impact	-1,4	medium_impact	1,47	0,74	0,9	48,67	8,91	N	0,31	N	0,97	polymorphism	0,6	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15723	15723	G	T	MI.10410	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	977	326	W	L	tGa/tTa	5,67	1	0	probably_damaging	1	neutral	0,87	neutral	3,08	neutral	-0,63	deleterious	-8	medium_impact	3,46	neutral	0,75	damaging	0,08	deleterious	2,69	20,7	0,05	0,35	neutral	0,36	disease	0,85	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,44	deleterious	1	deleterious	0,75	low_impact	-3,53	medium_impact	0,67	medium_impact	1,95	0,11	0,8	57,89	8,47	N	0,45	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15724	15724	A	C	MI.10411	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	978	326	W	C	tgA/tgC	7,27	1	0,02	probably_damaging	1	neutral	0,08	neutral	2,91	deleterious	-4,01	deleterious	-8	high_impact	4,59	neutral	0,77	damaging	0,05	deleterious	2,46	19,22	0,04	0,35	disease	0,8	disease	0,85	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	-0,35	high_impact	2,97	0,16	0,8	57,89	8,47	P	0,54	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15724	15724	A	T	MI.10412	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	978	326	W	C	tgA/tgT	7,27	1	0,02	probably_damaging	1	neutral	0,08	neutral	2,91	deleterious	-4,01	deleterious	-8	high_impact	4,59	neutral	0,77	damaging	0,05	deleterious	2,57	19,93	0,04	0,35	disease	0,8	disease	0,85	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	-0,35	high_impact	2,97	0,16	0,8	57,89	8,47	P	0,54	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15725	15725	C	T	MI.10413	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	979	327	L	F	Ctc/Ttc	4,52	0,99	0	benign	0,03	neutral	0,97	neutral	2,86	neutral	-1,77	neutral	-0,93	low_impact	1,26	neutral	0,93	neutral	0,9	neutral	1,39	12,72	0,25	0,45	disease	0,52	neutral	0,33	neutral	0,29	neutral	0,37	3	neutral	0	deleterious	0,97	neutral	-6	neutral	0,15	medium_impact	0,68	medium_impact	1,04	medium_impact	-0,05	0,59	0,8	16,58	16,73	N	0,43	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15725	15725	C	G	MI.10414	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	979	327	L	V	Ctc/Gtc	4,52	0,99	0	benign	0,17	neutral	0,57	neutral	2,96	neutral	-0,76	neutral	-0,14	low_impact	1,51	neutral	0,96	neutral	0,93	deleterious	0,43	6,9	0,31	0,45	neutral	0,33	neutral	0,19	neutral	0,28	neutral	0,38	3	neutral	0,32	deleterious	0,7	neutral	-6	neutral	0,13	medium_impact	-0,09	medium_impact	0,29	medium_impact	0,18	0,66	0,8	16,58	16,73	N	0,5	N	0,4	polymorphism	1	0,01	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15725	15725	C	A	MI.10415	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	979	327	L	I	Ctc/Atc	4,52	0,99	0	benign	0,36	neutral	0,77	neutral	2,97	neutral	-0,59	neutral	-0,21	neutral_impact	0,47	neutral	0,95	neutral	0,95	deleterious	0,24	5,1	0,31	0,45	neutral	0,22	neutral	0,12	neutral	0,22	neutral	0,28	4	neutral	0,25	deleterious	0,71	neutral	-6	neutral	0,15	medium_impact	-0,5	medium_impact	0,51	medium_impact	-0,77	0,61	0,8	16,58	16,73	N	0,47	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15726	15726	T	A	MI.10416	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	980	327	L	H	cTc/cAc	-5,79	0	0	probably_damaging	0,95	neutral	0,47	neutral	2,78	deleterious	-4,13	neutral	-1,85	high_impact	3,6	neutral	0,82	neutral	0,49	deleterious	2,8	21,3	0,06	0,35	disease	0,72	disease	0,53	disease	0,54	disease	0,62	2	neutral	0,95	neutral	0,26	deleterious	2	deleterious	0,69	low_impact	-1,92	medium_impact	0,19	high_impact	2,08	0,21	0,8	16,58	16,73	N	0,32	N	0,71	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15726	15726	T	C	MI.10417	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	980	327	L	P	cTc/cCc	-5,79	0	0	probably_damaging	0,97	neutral	0,18	neutral	2,78	deleterious	-4,12	neutral	-1,65	high_impact	3,6	neutral	0,83	neutral	0,38	deleterious	2,41	18,86	0,04	0,35	disease	0,72	disease	0,78	disease	0,6	disease	0,69	4	deleterious	0,98	neutral	0,11	deleterious	2	deleterious	0,79	low_impact	-2,14	medium_impact	-0,14	high_impact	2,08	0,29	0,8	16,58	16,73	N	0,3	N	0,94	polymorphism	1	0,09	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15726	15726	T	G	MI.10418	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	980	327	L	R	cTc/cGc	-5,79	0	0	probably_damaging	0,9	neutral	0,3	neutral	2,79	deleterious	-3,55	neutral	-1,46	high_impact	3,94	neutral	0,84	neutral	0,49	deleterious	2,69	20,7	0,04	0,35	disease	0,64	disease	0,7	disease	0,6	disease	0,67	3	neutral	0,92	neutral	0,2	deleterious	2	deleterious	0,68	low_impact	-1,62	medium_impact	0,02	high_impact	2,38	0,2	0,8	16,58	16,73	N	0,38	N	0,81	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15728	15728	C	A	MI.10419	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	982	328	L	M	Cta/Ata	-14,73	0	0	probably_damaging	0,97	neutral	0,39	neutral	2,77	neutral	-2,31	neutral	-0,83	medium_impact	2,21	neutral	0,87	damaging	0,1	deleterious	2,2	17,53	0,19	0,45	disease	0,52	neutral	0,36	neutral	0,41	neutral	0,3	4	neutral	0,97	neutral	0,21	deleterious	1	deleterious	0,68	low_impact	-2,14	medium_impact	0,12	medium_impact	0,81	0,59	0,8	55,26	8,58	N	0,32	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9016	9016	A	C	MI.1042	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	490	164	I	L	Att/Ctt	-3,34	0	0	probably_damaging	0,93	neutral	1	neutral	3,86	neutral	-1,54	neutral	-0,53	neutral_impact	-0,9	neutral	0,71	neutral	0,66	deleterious	0,89	9,99	0,38	0,65	neutral	0,44	neutral	0,16	neutral	0,27	neutral	0,25	5	neutral	0,93	deleterious	0,54	neutral	-2	deleterious	0,63	low_impact	-1,82	high_impact	1,98	low_impact	-1,87	0,71	0,9	48,67	8,91	N	0,25	N	0,83	polymorphism	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15728	15728	C	G	MI.10420	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	982	328	L	V	Cta/Gta	-14,73	0	0	possibly_damaging	0,49	neutral	0,39	neutral	2,82	neutral	-1,51	neutral	-1,52	high_impact	3,73	neutral	0,91	damaging	0,11	deleterious	1,88	15,46	0,21	0,45	neutral	0,39	neutral	0,39	disease	0,63	neutral	0,45	1	neutral	0,59	neutral	0,45	deleterious	1	deleterious	0,48	medium_impact	-0,72	medium_impact	0,12	high_impact	2,19	0,44	0,8	55,26	8,58	N	0,34	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15729	15729	T	A	MI.10421	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	983	328	L	Q	cTa/cAa	-0,98	0	0	probably_damaging	1	neutral	0,19	neutral	2,74	deleterious	-3,39	deleterious	-3,25	high_impact	4,42	neutral	0,86	damaging	0,07	deleterious	2,53	19,66	0,04	0,35	disease	0,69	disease	0,67	disease	0,63	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,74	low_impact	-3,53	medium_impact	-0,12	high_impact	2,82	0,35	0,8	55,26	8,58	N	0,39	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15729	15729	T	C	MI.10422	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	983	328	L	P	cTa/cCa	-0,98	0	0	probably_damaging	1	neutral	0,15	neutral	2,72	deleterious	-4,32	deleterious	-3,88	high_impact	4,76	neutral	0,87	damaging	0,05	deleterious	2,37	18,6	0,03	0,35	disease	0,76	disease	0,74	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,19	high_impact	3,13	0,32	0,8	55,26	8,58	P	0,66	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15729	15729	T	G	MI.10423	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	983	328	L	R	cTa/cGa	-0,98	0	0	probably_damaging	1	neutral	0,19	neutral	2,73	deleterious	-3,68	deleterious	-3,31	high_impact	4,76	neutral	0,87	damaging	0,06	deleterious	2,63	20,4	0,03	0,35	disease	0,67	disease	0,79	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,12	high_impact	3,13	0,22	0,8	55,26	8,58	P	0,67	P	0,99	polymorphism	1	0,19	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15731	15731	G	A	MI.10424	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	985	329	A	T	Gcc/Acc	-0,29	0	0	benign	0,01	neutral	0,31	neutral	2,97	neutral	-0,47	neutral	0,06	neutral_impact	0,22	neutral	0,99	neutral	0,95	neutral	1,36	12,6	0,17	0,45	neutral	0,25	neutral	0,22	neutral	0,35	neutral	0,36	3	neutral	0,69	deleterious	0,65	neutral	-6	neutral	0,09	medium_impact	1,13	medium_impact	0,03	medium_impact	-0,99	0,68	0,85	23,95	21,91	N	0,49	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15731	15731	G	C	MI.10425	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	985	329	A	P	Gcc/Ccc	-0,29	0	0	possibly_damaging	0,55	neutral	0,09	neutral	2,91	neutral	-2,6	neutral	-1,33	medium_impact	3	neutral	0,94	neutral	0,4	deleterious	2,26	17,92	0,04	0,35	disease	0,61	disease	0,85	disease	0,67	disease	0,77	5	neutral	0,9	neutral	0,27	NA	0	deleterious	0,43	medium_impact	-0,81	medium_impact	-0,32	medium_impact	1,53	0,52	0,8	23,95	21,91	N	0,39	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15731	15731	G	T	MI.10426	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	985	329	A	S	Gcc/Tcc	-0,29	0	0	benign	0,18	neutral	0,25	neutral	2,95	neutral	-0,88	neutral	-0,99	low_impact	1,62	neutral	0,94	neutral	0,65	deleterious	2,14	17,14	0,21	0,45	neutral	0,38	neutral	0,41	disease	0,53	neutral	0,47	1	neutral	0,7	deleterious	0,54	neutral	-6	neutral	0,18	medium_impact	-0,12	medium_impact	-0,04	medium_impact	0,28	0,34	0,8	23,95	21,91	N	0,42	N	0,61	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15732	15732	C	G	MI.10427	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	986	329	A	G	gCc/gGc	-1,44	0	0	benign	0,24	neutral	0,28	neutral	2,92	neutral	-1,8	neutral	-1,83	low_impact	1,9	neutral	0,97	neutral	0,63	deleterious	2,4	18,8	0,19	0,45	disease	0,53	neutral	0,46	disease	0,54	disease	0,51	0	neutral	0,66	deleterious	0,52	neutral	-6	neutral	0,21	medium_impact	-0,26	medium_impact	0	medium_impact	0,53	0,57	0,8	23,95	21,91	N	0,36	N	0,57	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15732	15732	C	A	MI.10428	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	986	329	A	D	gCc/gAc	-1,44	0	0	benign	0,34	neutral	0,12	neutral	2,9	deleterious	-3	neutral	-1,79	medium_impact	2,65	neutral	0,93	neutral	0,5	deleterious	3,01	22,3	0,03	0,35	disease	0,66	disease	0,78	disease	0,66	disease	0,74	5	neutral	0,86	neutral	0,39	neutral	-3	neutral	0,34	medium_impact	-0,46	medium_impact	-0,25	medium_impact	1,21	0,39	0,8	23,95	21,91	N	0,35	N	0,55	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15732	15732	C	T	MI.10429	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	986	329	A	V	gCc/gTc	-1,44	0	0	benign	0,01	neutral	0,65	neutral	3,3	neutral	2,04	neutral	1,75	neutral_impact	-1,61	neutral	0,99	neutral	0,98	deleterious	0,12	3,84	0,15	0,4	neutral	0,22	neutral	0,06	neutral	0,29	neutral	0,17	7	neutral	0,34	deleterious	0,82	neutral	-6	neutral	0,08	medium_impact	1,13	medium_impact	0,37	low_impact	-2,66	0,61	0,8	23,95	21,91	N	0,42	N	0,02	polymorphism	1	0,01	rs879129589	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	9016	9016	A	G	MI.1043	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	490	164	I	V	Att/Gtt	-3,34	0	0	probably_damaging	0,93	neutral	0,26	neutral	3,59	neutral	-1,58	neutral	-0,9	low_impact	1,48	neutral	0,9	neutral	0,5	deleterious	2,89	21,8	0,49	0,65	disease	0,75	neutral	0,38	disease	0,64	disease	0,69	4	neutral	0,95	neutral	0,17	neutral	-2	deleterious	0,69	low_impact	-1,82	medium_impact	0,04	medium_impact	0,17	0,61	0,9	48,67	8,91	N	0,48	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	CPD	0,15	A9016G	LHON	-	+	Reported	2
chrM	15734	15734	G	A	MI.10430	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	988	330	A	T	Gca/Aca	-6,71	0	0	benign	0,02	neutral	0,44	neutral	2,94	neutral	-1,32	neutral	-1,47	medium_impact	2,03	neutral	0,99	neutral	0,63	neutral	1,56	13,63	0,17	0,45	neutral	0,31	disease	0,56	neutral	0,34	neutral	0,33	3	neutral	0,54	deleterious	0,71	neutral	-3	neutral	0,12	medium_impact	0,85	medium_impact	0,17	medium_impact	0,65	0,75	0,85	22,63	39,24	N	0,41	N	0,02	polymorphism	1	0,03	rs386829259	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15734	15734	G	C	MI.10431	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	988	330	A	P	Gca/Cca	-6,71	0	0	probably_damaging	0,97	neutral	0,23	neutral	2,89	deleterious	-3,12	deleterious	-2,5	high_impact	3,51	neutral	0,94	neutral	0,29	deleterious	2,35	18,49	0,05	0,35	disease	0,74	disease	0,88	disease	0,68	disease	0,72	4	neutral	0,98	neutral	0,13	deleterious	2	deleterious	0,81	low_impact	-2,14	medium_impact	-0,06	medium_impact	1,99	0,47	0,8	22,63	39,24	N	0,38	N	0,82	polymorphism	1	0,05	rs386829259	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15734	15734	G	T	MI.10432	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	988	330	A	S	Gca/Tca	-6,71	0	0	benign	0,41	neutral	0,45	neutral	2,96	neutral	-1,31	neutral	-1,25	low_impact	1,43	neutral	0,97	neutral	0,72	neutral	0,97	10,51	0,21	0,45	neutral	0,47	disease	0,5	neutral	0,32	neutral	0,36	3	neutral	0,49	deleterious	0,52	neutral	-6	neutral	0,28	medium_impact	-0,58	medium_impact	0,18	medium_impact	0,11	0,45	0,8	22,63	39,24	N	0,32	N	0,56	polymorphism	1	0,03	rs386829259	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15735	15735	C	G	MI.10433	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	989	330	A	G	gCa/gGa	0,86	0,11	0	benign	0,2	neutral	0,37	neutral	2,91	neutral	-2,25	neutral	-2,15	medium_impact	2,27	neutral	0,93	neutral	0,52	deleterious	2,41	18,91	0,2	0,45	disease	0,67	disease	0,66	neutral	0,38	neutral	0,39	2	neutral	0,56	deleterious	0,59	neutral	-3	neutral	0,32	medium_impact	-0,17	medium_impact	0,1	medium_impact	0,87	0,56	0,8	22,63	39,24	N	0,33	N	0,64	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15735	15735	C	A	MI.10434	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	989	330	A	E	gCa/gAa	0,86	0,11	0	probably_damaging	0,95	neutral	0,33	neutral	2,89	neutral	-2,79	neutral	-2,47	high_impact	4,21	neutral	0,93	neutral	0,42	deleterious	2,95	22	0,04	0,35	disease	0,61	disease	0,87	disease	0,68	disease	0,72	4	neutral	0,96	neutral	0,19	deleterious	2	deleterious	0,77	low_impact	-1,92	medium_impact	0,06	high_impact	2,63	0,33	0,8	22,63	39,24	N	0,45	N	0,85	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15735	15735	C	T	MI.10435	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	989	330	A	V	gCa/gTa	0,86	0,11	0	benign	0,02	neutral	0,57	neutral	3,08	neutral	0,38	neutral	-1,72	medium_impact	2,08	neutral	0,97	neutral	0,57	deleterious	2,93	22	0,13	0,4	neutral	0,32	disease	0,74	neutral	0,39	neutral	0,42	2	neutral	0,4	deleterious	0,78	neutral	-3	neutral	0,16	medium_impact	0,85	medium_impact	0,29	medium_impact	0,7	0,69	0,85	22,63	39,24	N	0,27	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15737	15737	G	T	MI.10436	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	991	331	D	Y	Gac/Tac	-6,02	0	0	probably_damaging	0,93	neutral	1	neutral	3,13	neutral	-0,85	deleterious	-3,36	high_impact	4,04	neutral	0,91	neutral	0,54	deleterious	2,35	18,49	0,07	0,35	disease	0,67	disease	0,91	disease	0,59	disease	0,67	3	neutral	0,93	deleterious	0,54	deleterious	2	deleterious	0,79	low_impact	-1,78	high_impact	1,85	high_impact	2,48	0,11	0,8	24,74	40,07	N	0,27	N	0,93	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15737	15737	G	A	MI.10437	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	991	331	D	N	Gac/Aac	-6,02	0	0	benign	0,01	neutral	0,44	neutral	3,2	neutral	0,45	neutral	0,1	neutral_impact	-0,27	neutral	0,88	neutral	0,94	deleterious	0,68	8,66	0,33	0,5	neutral	0,25	neutral	0,26	neutral	0,34	neutral	0,41	2	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,14	medium_impact	1,13	medium_impact	0,17	low_impact	-1,44	0,7	0,85	24,74	40,07	N	0,37	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15737	15737	G	C	MI.10438	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	991	331	D	H	Gac/Cac	-6,02	0	0	possibly_damaging	0,89	neutral	0,56	neutral	3,1	neutral	-1,78	neutral	-1,96	high_impact	3,69	neutral	0,9	neutral	0,44	deleterious	2,1	16,87	0,1	0,4	disease	0,56	disease	0,82	disease	0,66	disease	0,66	3	neutral	0,88	neutral	0,34	deleterious	1	deleterious	0,71	low_impact	-1,58	medium_impact	0,28	high_impact	2,16	0,24	0,8	24,74	40,07	N	0,29	N	0,48	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15738	15738	A	C	MI.10439	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	992	331	D	A	gAc/gCc	0,4	0,03	0	benign	0,31	neutral	0,78	neutral	3,18	neutral	0,19	deleterious	-3,06	medium_impact	2,27	neutral	0,92	neutral	0,56	deleterious	2,05	16,53	0,11	0,4	neutral	0,34	disease	0,81	neutral	0,49	disease	0,62	2	neutral	0,2	deleterious	0,74	neutral	-3	neutral	0,43	medium_impact	-0,41	medium_impact	0,52	medium_impact	0,87	0,26	0,8	24,74	40,07	N	0,23	N	0,64	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9017	9017	T	C	MI.1044	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	491	164	I	T	aTt/aCt	1,29	0,73	0	probably_damaging	0,99	deleterious	0	neutral	3,47	deleterious	-3,9	deleterious	-3,81	medium_impact	2,46	neutral	0,82	neutral	0,45	deleterious	3,43	23	0,35	0,65	disease	0,92	disease	0,55	disease	0,65	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,82	low_impact	-2,65	low_impact	-1,4	medium_impact	1,01	0,65	0,9	48,67	8,91	N	0,28	N	0,99	polymorphism	0,98	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15738	15738	A	G	MI.10440	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	992	331	D	G	gAc/gGc	0,4	0,03	0	possibly_damaging	0,5	neutral	0,45	neutral	3,13	neutral	-0,87	neutral	-2,29	medium_impact	3,49	neutral	0,91	neutral	0,46	deleterious	2,38	18,67	0,1	0,4	disease	0,52	disease	0,81	disease	0,57	disease	0,64	3	neutral	0,54	deleterious	0,48	NA	0	neutral	0,4	medium_impact	-0,73	medium_impact	0,18	medium_impact	1,98	0,29	0,8	24,74	40,07	N	0,34	N	0,43	polymorphism	1	0,03	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15738	15738	A	T	MI.10441	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	992	331	D	V	gAc/gTc	0,4	0,03	0	benign	0,18	neutral	0,68	neutral	3,2	neutral	0,39	deleterious	-3,53	low_impact	1,54	neutral	0,93	neutral	0,86	deleterious	2,11	16,89	0,07	0,35	neutral	0,39	disease	0,86	neutral	0,37	neutral	0,49	0	neutral	0,2	deleterious	0,75	neutral	-6	neutral	0,28	medium_impact	-0,12	medium_impact	0,4	medium_impact	0,21	0,11	0,8	24,74	40,07	N	0,25	N	0,8	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15739	15739	C	A	MI.10442	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	993	331	D	E	gaC/gaA	3,83	0,43	0	benign	0,13	neutral	0,48	neutral	3,11	neutral	-1,23	neutral	-1,41	high_impact	4,04	neutral	0,9	neutral	0,49	deleterious	2,72	20,9	0,2	0,45	neutral	0,3	disease	0,81	disease	0,54	disease	0,64	3	neutral	0,44	deleterious	0,68	neutral	-2	neutral	0,24	medium_impact	0,04	medium_impact	0,2	high_impact	2,48	0,55	0,8	24,74	40,07	N	0,42	N	0,42	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15739	15739	C	G	MI.10443	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	993	331	D	E	gaC/gaG	3,83	0,43	0	benign	0,13	neutral	0,48	neutral	3,11	neutral	-1,23	neutral	-1,41	high_impact	4,04	neutral	0,9	neutral	0,49	deleterious	2,38	18,71	0,2	0,45	neutral	0,3	disease	0,81	disease	0,54	disease	0,64	3	neutral	0,44	deleterious	0,68	neutral	-2	neutral	0,24	medium_impact	0,04	medium_impact	0,2	high_impact	2,48	0,55	0,8	24,74	40,07	N	0,42	N	0,42	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15740	15740	C	A	MI.10444	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	994	332	L	I	Ctc/Atc	-0,98	0	0	probably_damaging	0,99	neutral	0,5	neutral	2,97	neutral	-0,3	neutral	0	low_impact	0,94	neutral	0,81	neutral	0,46	neutral	1,48	13,23	0,32	0,5	neutral	0,36	neutral	0,29	neutral	0,24	neutral	0,45	1	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,67	low_impact	-2,59	medium_impact	0,22	medium_impact	-0,34	0,5	0,8	58,16	9,29	N	0,31	N	0,86	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15740	15740	C	T	MI.10445	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	994	332	L	F	Ctc/Ttc	-0,98	0	0	probably_damaging	1	neutral	0,73	neutral	3,14	neutral	0,96	neutral	-1,58	neutral_impact	0,23	neutral	0,84	neutral	0,47	deleterious	2,38	18,68	0,24	0,45	neutral	0,27	disease	0,53	neutral	0,28	neutral	0,25	5	deleterious	1	neutral	0,37	neutral	-2	deleterious	0,68	low_impact	-3,53	medium_impact	0,46	medium_impact	-0,98	0,5	0,8	58,16	9,29	N	0,19	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15740	15740	C	G	MI.10446	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	994	332	L	V	Ctc/Gtc	-0,98	0	0	probably_damaging	0,98	neutral	0,65	neutral	2,99	neutral	-0,13	neutral	-0,15	neutral_impact	0,51	neutral	0,91	neutral	0,53	deleterious	0,47	7,23	0,34	0,5	neutral	0,26	neutral	0,08	neutral	0,25	neutral	0,24	5	neutral	0,97	neutral	0,34	neutral	-2	deleterious	0,64	low_impact	-2,31	medium_impact	0,37	medium_impact	-0,73	0,54	0,8	58,16	9,29	N	0,36	N	0,91	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15741	15741	T	A	MI.10447	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	995	332	L	H	cTc/cAc	-0,06	0	0	probably_damaging	1	neutral	0,53	neutral	2,85	deleterious	-3,01	deleterious	-3,06	high_impact	3,94	neutral	0,82	neutral	0,31	deleterious	2,6	20,2	0,04	0,35	disease	0,71	disease	0,68	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,25	high_impact	2,38	0,23	0,8	58,16	9,29	N	0,26	N	0,95	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15741	15741	T	C	MI.10448	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	995	332	L	P	cTc/cCc	-0,06	0	0	probably_damaging	1	neutral	0,24	neutral	2,85	deleterious	-3,07	deleterious	-2,89	high_impact	3,6	neutral	0,83	damaging	0,27	deleterious	2,37	18,6	0,02	0,35	disease	0,71	disease	0,86	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,05	high_impact	2,08	0,16	0,8	58,16	9,29	N	0,31	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15741	15741	T	G	MI.10449	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	995	332	L	R	cTc/cGc	-0,06	0	0	probably_damaging	1	neutral	0,35	neutral	2,86	neutral	-2,42	deleterious	-2,71	medium_impact	3,4	neutral	0,84	neutral	0,31	deleterious	2,68	20,7	0,02	0,35	disease	0,63	disease	0,84	disease	0,66	disease	0,73	5	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,83	low_impact	-3,53	medium_impact	0,08	medium_impact	1,89	0,24	0,8	58,16	9,29	N	0,27	N	0,99	polymorphism	1	0,08	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	9017	9017	T	A	MI.1045	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	491	164	I	N	aTt/aAt	1,29	0,73	0	probably_damaging	1	deleterious	0	neutral	3,46	deleterious	-6,17	deleterious	-5,65	medium_impact	3	neutral	0,82	neutral	0,43	deleterious	4,47	24,2	0,26	0,65	disease	0,98	disease	0,81	disease	0,65	disease	0,85	7	deleterious	1	neutral	0	deleterious	5	deleterious	0,86	low_impact	-3,6	low_impact	-1,4	medium_impact	1,47	0,64	0,9	48,67	8,91	N	0,31	N	1	polymorphism	0,93	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15743	15743	C	T	MI.10450	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	997	333	L	F	Ctc/Ttc	-10,6	0	0	probably_damaging	1	neutral	0,79	neutral	2,91	neutral	-0,64	neutral	-1,5	low_impact	0,83	neutral	0,94	neutral	0,94	neutral	1,1	11,23	0,18	0,45	neutral	0,37	neutral	0,31	neutral	0,37	neutral	0,44	1	deleterious	1	neutral	0,4	neutral	-2	neutral	0,15	low_impact	-3,53	medium_impact	0,53	medium_impact	-0,44	0,52	0,8	19,21	17,39	N	0,29	N	0,97	polymorphism	1	0,03	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15743	15743	C	G	MI.10451	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	997	333	L	V	Ctc/Gtc	-10,6	0	0	probably_damaging	0,98	neutral	0,57	neutral	2,93	neutral	-0,45	neutral	-0,97	low_impact	1,28	neutral	0,94	neutral	0,85	deleterious	0,83	9,65	0,28	0,45	neutral	0,3	neutral	0,32	neutral	0,36	neutral	0,43	1	neutral	0,97	neutral	0,3	neutral	-2	neutral	0,16	low_impact	-2,31	medium_impact	0,29	medium_impact	-0,03	0,55	0,8	19,21	17,39	N	0,34	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15743	15743	C	A	MI.10452	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	997	333	L	I	Ctc/Atc	-10,6	0	0	probably_damaging	0,99	neutral	0,67	neutral	2,94	neutral	-0,37	neutral	-0,51	neutral_impact	0,68	neutral	0,91	neutral	0,91	neutral	1,24	11,97	0,27	0,45	neutral	0,28	neutral	0,2	neutral	0,28	neutral	0,34	3	deleterious	0,99	neutral	0,34	neutral	-2	neutral	0,18	low_impact	-2,59	medium_impact	0,39	medium_impact	-0,58	0,46	0,8	19,21	17,39	N	0,34	N	0,86	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15744	15744	T	A	MI.10453	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	998	333	L	H	cTc/cAc	-5,33	0	0	probably_damaging	1	neutral	0,46	neutral	2,75	deleterious	-3,85	deleterious	-3,37	high_impact	3,94	neutral	0,82	neutral	0,45	deleterious	2,61	20,2	0,05	0,35	disease	0,73	disease	0,68	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,71	low_impact	-3,53	medium_impact	0,18	high_impact	2,38	0,22	0,8	19,21	17,39	N	0,34	N	0,95	polymorphism	1	0,19	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15744	15744	T	G	MI.10454	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	998	333	L	R	cTc/cGc	-5,33	0	0	probably_damaging	1	neutral	0,3	neutral	2,76	deleterious	-3,3	deleterious	-3,04	high_impact	4,29	neutral	0,84	neutral	0,44	deleterious	2,66	20,6	0,02	0,35	disease	0,65	disease	0,83	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,75	low_impact	-3,53	medium_impact	0,02	high_impact	2,7	0,18	0,8	19,21	17,39	N	0,42	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15744	15744	T	C	MI.10455	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	998	333	L	P	cTc/cCc	-5,33	0	0	probably_damaging	1	neutral	0,29	neutral	2,75	deleterious	-3,89	deleterious	-3,47	high_impact	3,94	neutral	0,83	neutral	0,33	deleterious	2,36	18,59	0,03	0,35	disease	0,74	disease	0,84	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,01	high_impact	2,38	0,28	0,8	19,21	17,39	N	0,35	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15746	15746	A	G	MI.10456	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1000	334	I	V	Att/Gtt	-11,75	0	0,01	benign	0	neutral	0,58	neutral	3,01	neutral	0,2	neutral	-0,38	low_impact	1,02	neutral	0,94	neutral	0,89	deleterious	0,28	5,48	0,52	0,6	neutral	0,3	neutral	0,22	neutral	0,38	neutral	0,38	2	neutral	0,42	deleterious	0,79	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,3	medium_impact	-0,27	0,39	0,8	17,63	23,86	N	0,35	N	0,71	polymorphism	1	0,01	rs386829260	Benign	not_provided	RCV000224723.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	15746	15746	A	C	MI.10457	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1000	334	I	L	Att/Ctt	-11,75	0	0,01	benign	0,06	neutral	1	neutral	3,06	neutral	-0,34	neutral	-0,89	low_impact	0,86	neutral	0,9	neutral	0,71	deleterious	2,23	17,73	0,28	0,45	neutral	0,17	disease	0,59	neutral	0,27	neutral	0,27	5	neutral	0,06	deleterious	0,97	neutral	-6	neutral	0,12	medium_impact	0,38	high_impact	1,85	medium_impact	-0,41	0,46	0,8	17,63	23,86	N	0,3	N	0,62	polymorphism	1	0,02	rs386829260	Benign	not_provided	RCV000224723.1	MedGen	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15746	15746	A	T	MI.10458	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1000	334	I	F	Att/Ttt	-11,75	0	0,01	possibly_damaging	0,45	neutral	0,63	neutral	2,9	neutral	-1,6	neutral	-2,15	medium_impact	2,77	neutral	0,85	neutral	0,55	deleterious	2,25	17,86	0,18	0,45	neutral	0,41	disease	0,79	disease	0,54	disease	0,65	3	neutral	0,38	deleterious	0,59	NA	0	neutral	0,37	medium_impact	-0,65	medium_impact	0,35	medium_impact	1,32	0,49	0,8	17,63	23,86	N	0,22	N	0,67	polymorphism	1	0,03	rs386829260	Benign	not_provided	RCV000224723.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	15747	15747	T	G	MI.10459	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1001	334	I	S	aTt/aGt	0,4	0	0	benign	0,36	neutral	0,34	neutral	2,88	neutral	-1,87	deleterious	-3,02	medium_impact	3,12	neutral	0,84	neutral	0,51	deleterious	2,75	21,1	0,04	0,35	disease	0,51	disease	0,81	disease	0,56	disease	0,65	3	neutral	0,6	deleterious	0,49	neutral	-3	neutral	0,33	medium_impact	-0,5	medium_impact	0,07	medium_impact	1,64	0,21	0,8	17,63	23,86	N	0,3	N	0,54	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9017	9017	T	G	MI.1046	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	491	164	I	S	aTt/aGt	1,29	0,73	0	probably_damaging	0,99	deleterious	0	neutral	3,46	deleterious	-5,01	deleterious	-4,71	medium_impact	3	neutral	0,8	neutral	0,49	deleterious	4,32	24	0,23	0,65	disease	0,96	disease	0,76	disease	0,63	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,85	low_impact	-2,65	low_impact	-1,4	medium_impact	1,47	0,5	0,9	48,67	8,91	N	0,28	N	0,98	polymorphism	0,91	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15747	15747	T	A	MI.10460	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1001	334	I	N	aTt/aAt	0,4	0	0	possibly_damaging	0,48	neutral	0,2	neutral	2,84	neutral	-2,44	deleterious	-3,63	high_impact	4,13	neutral	0,83	neutral	0,53	deleterious	2,89	21,8	0,09	0,35	disease	0,69	disease	0,86	disease	0,6	disease	0,7	4	neutral	0,78	neutral	0,36	deleterious	1	deleterious	0,49	medium_impact	-0,7	medium_impact	-0,1	high_impact	2,56	0,29	0,8	17,63	23,86	N	0,41	N	0,76	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15747	15747	T	C	MI.10461	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1001	334	I	T	aTt/aCt	0,4	0	0	benign	0,01	neutral	0,65	neutral	2,9	neutral	-1,54	neutral	-2,19	low_impact	1,45	neutral	0,97	neutral	0,95	neutral	-0,32	0,59	0,1	0,4	neutral	0,31	neutral	0,37	neutral	0,42	neutral	0,44	1	neutral	0,32	deleterious	0,82	neutral	-6	neutral	0,11	medium_impact	1,13	medium_impact	0,37	medium_impact	0,12	0,19	0,8	17,63	23,86	N	0,27	N	0,04	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15748	15748	T	A	MI.10462	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1002	334	I	M	atT/atA	1,31	0	0	possibly_damaging	0,69	neutral	0,33	neutral	2,9	neutral	-1,85	neutral	-1,4	medium_impact	2,68	neutral	0,9	neutral	0,47	deleterious	2,21	17,56	0,37	0,5	disease	0,51	disease	0,58	neutral	0,39	neutral	0,38	2	neutral	0,75	neutral	0,32	NA	0	neutral	0,39	low_impact	-1,06	medium_impact	0,06	medium_impact	1,24	0,52	0,8	17,63	23,86	N	0,37	N	0,77	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15748	15748	T	G	MI.10463	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1002	334	I	M	atT/atG	1,31	0	0	possibly_damaging	0,69	neutral	0,33	neutral	2,9	neutral	-1,85	neutral	-1,4	medium_impact	2,68	neutral	0,9	neutral	0,47	deleterious	1,86	15,33	0,37	0,5	disease	0,51	disease	0,58	neutral	0,39	neutral	0,38	2	neutral	0,75	neutral	0,32	NA	0	neutral	0,39	low_impact	-1,06	medium_impact	0,06	medium_impact	1,24	0,52	0,8	17,63	23,86	N	0,37	N	0,77	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15749	15749	C	A	MI.10464	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1003	335	L	M	Cta/Ata	-5,79	0	0	probably_damaging	1	neutral	0,23	neutral	1,81	deleterious	-4,79	neutral	-1,21	high_impact	4,39	neutral	0,87	damaging	0,1	deleterious	2,18	17,4	0,18	0,45	disease	0,8	disease	0,56	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	-0,06	high_impact	2,79	0,54	0,8	56,58	8,6	N	0,44	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15749	15749	C	G	MI.10465	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1003	335	L	V	Cta/Gta	-5,79	0	0	probably_damaging	0,99	neutral	0,66	neutral	1,85	deleterious	-4,05	neutral	-1,82	high_impact	4,94	neutral	0,87	damaging	0,11	deleterious	1,88	15,45	0,16	0,45	disease	0,72	disease	0,57	disease	0,73	disease	0,7	4	deleterious	0,99	neutral	0,34	deleterious	2	deleterious	0,78	low_impact	-2,59	medium_impact	0,38	high_impact	3,29	0,56	0,8	56,58	8,6	P	0,64	P	0,91	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15750	15750	T	C	MI.10466	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1004	335	L	P	cTa/cCa	1,77	0,88	0	probably_damaging	1	neutral	0,25	neutral	1,74	deleterious	-7,89	deleterious	-4,25	high_impact	5,29	neutral	0,87	damaging	0,05	deleterious	2,32	18,32	0,02	0,35	disease	0,91	disease	0,79	disease	0,81	disease	0,76	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,04	high_impact	3,61	0,35	0,8	56,58	8,6	P	0,66	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15750	15750	T	G	MI.10467	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1004	335	L	R	cTa/cGa	1,77	0,88	0	probably_damaging	1	neutral	0,16	neutral	1,75	deleterious	-7,27	deleterious	-3,64	high_impact	5,29	neutral	0,87	damaging	0,06	deleterious	2,55	19,81	0,02	0,35	disease	0,72	disease	0,86	disease	0,81	disease	0,72	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,17	high_impact	3,61	0,22	0,8	56,58	8,6	P	0,67	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15750	15750	T	A	MI.10468	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1004	335	L	Q	cTa/cAa	1,77	0,88	0	probably_damaging	1	neutral	0,19	neutral	1,75	deleterious	-7,29	deleterious	-3,64	high_impact	4,94	neutral	0,86	damaging	0,07	deleterious	2,44	19,08	0,02	0,35	disease	0,82	disease	0,76	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,12	high_impact	3,29	0,32	0,8	56,58	8,6	P	0,65	P	0,98	polymorphism	1	0,2	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15752	15752	A	T	MI.10469	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1006	336	T	S	Acc/Tcc	-6,71	0	0	probably_damaging	0,98	neutral	0,23	neutral	2,88	neutral	-1,95	neutral	-2,42	medium_impact	3,43	neutral	0,84	neutral	0,49	neutral	1,77	14,8	0,29	0,45	neutral	0,42	disease	0,74	disease	0,63	disease	0,65	3	deleterious	0,98	neutral	0,13	deleterious	1	deleterious	0,74	low_impact	-2,31	medium_impact	-0,06	medium_impact	1,92	0,62	0,8	58,42	8,25	N	0,31	N	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9018	9018	T	A	MI.1047	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	492	164	I	M	atT/atA	7,53	0,98	0,01	probably_damaging	1	neutral	0,69	neutral	3,86	neutral	0,82	neutral	-1,74	neutral_impact	0,28	neutral	0,82	neutral	0,43	deleterious	3,7	23,3	0,5	0,65	neutral	0,29	neutral	0,27	neutral	0,3	neutral	0,44	1	deleterious	0,99	neutral	0,35	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	0,49	medium_impact	-0,86	0,84	0,9	48,67	8,91	N	0,45	N	0,75	polymorphism	0,95	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15752	15752	A	C	MI.10470	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1006	336	T	P	Acc/Ccc	-6,71	0	0	probably_damaging	1	neutral	0,3	neutral	2,79	deleterious	-3,89	deleterious	-3,63	high_impact	4,69	neutral	0,84	neutral	0,32	deleterious	1,94	15,83	0,05	0,35	disease	0,75	disease	0,85	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,02	high_impact	3,07	0,35	0,8	58,42	8,25	P	0,67	P	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15752	15752	A	G	MI.10471	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1006	336	T	A	Acc/Gcc	-6,71	0	0	probably_damaging	0,98	neutral	0,39	neutral	2,87	neutral	-2,09	deleterious	-3,02	high_impact	3,75	neutral	0,78	neutral	0,54	deleterious	1,98	16,05	0,13	0,4	neutral	0,42	disease	0,71	disease	0,67	disease	0,66	3	neutral	0,98	neutral	0,21	deleterious	2	deleterious	0,73	low_impact	-2,31	medium_impact	0,12	high_impact	2,21	0,31	0,8	58,42	8,25	N	0,33	N	0,59	polymorphism	1	0,05	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15753	15753	C	T	MI.10472	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1007	336	T	I	aCc/aTc	8,42	1	0	probably_damaging	1	neutral	0,53	neutral	2,84	neutral	-2,58	deleterious	-3,63	high_impact	3,88	neutral	0,84	neutral	0,48	deleterious	2,39	18,73	0,1	0,4	disease	0,53	disease	0,88	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,25	high_impact	2,33	0,57	0,8	58,42	8,25	N	0,52	P	0,83	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15753	15753	C	G	MI.10473	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1007	336	T	S	aCc/aGc	8,42	1	0	probably_damaging	0,98	neutral	0,23	neutral	2,88	neutral	-1,95	neutral	-2,42	medium_impact	3,43	neutral	0,84	neutral	0,49	deleterious	1,96	15,95	0,29	0,45	neutral	0,42	disease	0,74	disease	0,63	disease	0,65	3	deleterious	0,98	neutral	0,13	deleterious	1	deleterious	0,74	low_impact	-2,31	medium_impact	-0,06	medium_impact	1,92	0,62	0,8	58,42	8,25	P	0,53	P	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15753	15753	C	A	MI.10474	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1007	336	T	N	aCc/aAc	8,42	1	0	probably_damaging	1	neutral	0,17	neutral	2,79	deleterious	-3,77	deleterious	-3,02	high_impact	4,69	neutral	0,83	neutral	0,44	deleterious	2,26	17,92	0,21	0,45	disease	0,65	disease	0,86	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	-0,15	high_impact	3,07	0,5	0,8	58,42	8,25	P	0,67	P	0,84	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15755	15755	T	G	MI.10475	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1009	337	W	G	Tga/Gga	-0,75	0,17	0	probably_damaging	1	neutral	0,33	neutral	2,75	deleterious	-3,46	deleterious	-7,81	high_impact	4,72	neutral	0,75	damaging	0,13	deleterious	2,41	18,9	0,04	0,35	disease	0,65	disease	0,85	disease	0,81	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,06	high_impact	3,09	0,09	0,8	57,89	8,66	P	0,65	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15755	15755	T	C	MI.10476	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1009	337	W	R	Tga/Cga	-0,75	0,17	0	probably_damaging	1	neutral	0,35	neutral	2,75	deleterious	-3,32	deleterious	-8,41	high_impact	4,52	neutral	0,81	damaging	0,07	deleterious	2,02	16,35	0,03	0,35	disease	0,64	disease	0,92	disease	0,85	disease	0,78	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,08	high_impact	2,91	0,12	0,8	57,89	8,66	N	0,54	P	0,99	polymorphism	1	0,11	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15756	15756	G	C	MI.10477	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1010	337	W	S	tGa/tCa	7,27	1	0	probably_damaging	1	neutral	0,4	neutral	2,78	neutral	-2,43	deleterious	-8,41	high_impact	4,38	neutral	0,74	damaging	0,1	deleterious	2,48	19,37	0,04	0,35	disease	0,53	disease	0,91	disease	0,8	disease	0,75	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,13	high_impact	2,78	0,07	0,8	57,89	8,66	P	0,59	P	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15756	15756	G	T	MI.10478	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1010	337	W	L	tGa/tTa	7,27	1	0	probably_damaging	1	neutral	0,65	neutral	2,87	neutral	-0,99	deleterious	-7,81	high_impact	4,09	neutral	0,75	damaging	0,08	deleterious	2,7	20,8	0,04	0,35	neutral	0,36	disease	0,88	disease	0,79	disease	0,73	5	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,37	high_impact	2,52	0,07	0,8	57,89	8,66	P	0,55	P	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15757	15757	A	C	MI.10479	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1011	337	W	C	tgA/tgC	8,88	1	0,01	probably_damaging	1	neutral	0,18	neutral	2,74	deleterious	-3,86	deleterious	-7,81	high_impact	4,38	neutral	0,77	damaging	0,05	deleterious	2,48	19,32	0,03	0,35	disease	0,74	disease	0,9	disease	0,85	disease	0,78	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,14	high_impact	2,78	0,08	0,8	57,89	8,66	P	0,55	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9018	9018	T	G	MI.1048	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	492	164	I	M	atT/atG	7,53	0,98	0,01	probably_damaging	1	neutral	0,69	neutral	3,86	neutral	0,82	neutral	-1,74	neutral_impact	0,28	neutral	0,82	neutral	0,43	deleterious	3,41	23	0,5	0,65	neutral	0,29	neutral	0,27	neutral	0,3	neutral	0,44	1	deleterious	0,99	neutral	0,35	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	0,49	medium_impact	-0,86	0,84	0,9	48,67	8,91	N	0,45	N	0,75	polymorphism	0,95	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15757	15757	A	T	MI.10480	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1011	337	W	C	tgA/tgT	8,88	1	0,01	probably_damaging	1	neutral	0,18	neutral	2,74	deleterious	-3,86	deleterious	-7,81	high_impact	4,38	neutral	0,77	damaging	0,05	deleterious	2,62	20,3	0,03	0,35	disease	0,74	disease	0,9	disease	0,85	disease	0,78	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,14	high_impact	2,78	0,08	0,8	57,89	8,66	P	0,56	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15758	15758	A	G	MI.10481	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1012	338	I	V	Atc/Gtc	5,44	1	0,05	benign	0,01	neutral	0,5	neutral	2,95	neutral	-0,35	neutral	-0,44	medium_impact	1,98	neutral	0,89	neutral	0,57	neutral	1,58	13,73	0,39	0,5	neutral	0,31	neutral	0,44	neutral	0,49	neutral	0,4	2	neutral	0,49	deleterious	0,75	neutral	-3	neutral	0,15	medium_impact	1,13	medium_impact	0,22	medium_impact	0,6	0,57	0,8	49,74	7,97	P	0,61	P	0,83	polymorphism	1	0,01	rs527236193	Likely pathogenic	Familial_cancer_of_breast	RCV000133437.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	0,74	.	.	.	.	.	.
chrM	15758	15758	A	T	MI.10482	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1012	338	I	F	Atc/Ttc	5,44	1	0,05	possibly_damaging	0,79	neutral	0,71	neutral	2,81	neutral	-2,16	neutral	-2,37	medium_impact	3,44	neutral	0,85	neutral	0,36	deleterious	2,33	18,36	0,08	0,35	disease	0,55	disease	0,85	disease	0,71	disease	0,73	5	neutral	0,75	neutral	0,46	NA	0	deleterious	0,75	low_impact	-1,27	medium_impact	0,43	medium_impact	1,93	0,66	0,8	49,74	7,97	N	0,49	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15758	15758	A	C	MI.10483	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1012	338	I	L	Atc/Ctc	5,44	1	0,05	benign	0,15	neutral	0,7	neutral	3,13	neutral	0,65	neutral	-1,16	low_impact	1,37	neutral	0,84	neutral	0,34	deleterious	2,34	18,46	0,22	0,45	neutral	0,21	disease	0,72	neutral	0,41	neutral	0,49	0	neutral	0,18	deleterious	0,78	neutral	-6	neutral	0,19	medium_impact	-0,03	medium_impact	0,42	medium_impact	0,05	0,61	0,8	49,74	7,97	N	0,43	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15759	15759	T	G	MI.10484	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1013	338	I	S	aTc/aGc	3,61	1	0	probably_damaging	0,95	neutral	0,44	neutral	2,81	neutral	-2,16	deleterious	-3,47	high_impact	3,75	neutral	0,84	neutral	0,38	deleterious	2,82	21,5	0,03	0,35	neutral	0,49	disease	0,87	disease	0,71	disease	0,74	5	neutral	0,95	neutral	0,25	deleterious	2	deleterious	0,74	low_impact	-1,92	medium_impact	0,17	high_impact	2,21	0,23	0,8	49,74	7,97	N	0,45	N	0,98	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15759	15759	T	A	MI.10485	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1013	338	I	N	aTc/aAc	3,61	1	0	probably_damaging	0,97	neutral	0,31	neutral	2,78	deleterious	-3,43	deleterious	-4,08	high_impact	4,44	neutral	0,83	neutral	0,36	deleterious	3,05	22,4	0,06	0,35	disease	0,63	disease	0,89	disease	0,69	disease	0,73	5	neutral	0,98	neutral	0,17	deleterious	2	deleterious	0,81	low_impact	-2,14	medium_impact	0,03	high_impact	2,84	0,27	0,8	49,74	7,97	P	0,54	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15759	15759	T	C	MI.10486	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1013	338	I	T	aTc/aCc	3,61	1	0	benign	0,38	neutral	0,42	neutral	2,83	neutral	-1,77	deleterious	-2,8	medium_impact	3,46	neutral	0,74	neutral	0,41	deleterious	1,97	16,01	0,05	0,35	neutral	0,36	disease	0,79	disease	0,68	disease	0,68	4	neutral	0,51	deleterious	0,52	neutral	-3	neutral	0,3	medium_impact	-0,53	medium_impact	0,15	medium_impact	1,95	0,25	0,8	49,74	7,97	N	0,45	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15760	15760	C	A	MI.10487	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1014	338	I	M	atC/atA	7,27	1	0	possibly_damaging	0,89	neutral	0,22	neutral	2,83	neutral	-1,75	neutral	-1,68	high_impact	3,59	neutral	0,9	neutral	0,37	deleterious	2,33	18,37	0,12	0,4	disease	0,55	disease	0,71	disease	0,61	disease	0,65	3	neutral	0,93	neutral	0,17	deleterious	1	deleterious	0,53	low_impact	-1,58	medium_impact	-0,08	high_impact	2,07	0,67	0,85	49,74	7,97	P	0,57	P	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15760	15760	C	G	MI.10488	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1014	338	I	M	atC/atG	7,27	1	0	possibly_damaging	0,89	neutral	0,22	neutral	2,83	neutral	-1,75	neutral	-1,68	high_impact	3,59	neutral	0,9	neutral	0,37	deleterious	1,83	15,19	0,12	0,4	disease	0,55	disease	0,71	disease	0,61	disease	0,65	3	neutral	0,93	neutral	0,17	deleterious	1	deleterious	0,53	low_impact	-1,58	medium_impact	-0,08	high_impact	2,07	0,67	0,85	49,74	7,97	P	0,56	P	0,83	polymorphism	1	0,03	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15761	15761	G	T	MI.10489	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1015	339	G	W	Gga/Tga	-5,56	0	0	probably_damaging	1	neutral	0,2	neutral	1,77	deleterious	-10,02	deleterious	-4,8	high_impact	5,27	neutral	0,86	damaging	0,05	deleterious	2,86	21,7	0,04	0,35	disease	0,97	disease	0,92	disease	0,81	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,92	low_impact	-3,53	medium_impact	-0,1	high_impact	3,59	0,04	0,8	58,42	8,46	P	0,64	P	1	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9019	9019	A	C	MI.1049	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	493	165	T	P	Act/Cct	-9,59	0	0	probably_damaging	1	deleterious	0,01	neutral	4,23	deleterious	-3,38	deleterious	-5,47	high_impact	4,1	damaging	0,47	neutral	0,5	deleterious	3,54	23,1	0,12	0,65	disease	0,85	disease	0,91	disease	0,76	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,6	medium_impact	-0,84	high_impact	2,42	0,57	0,9	48,67	8,72	N	0,45	N	0,99	polymorphism	0,6	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15761	15761	G	C	MI.10490	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1015	339	G	R	Gga/Cga	-5,56	0	0	probably_damaging	1	neutral	0,33	neutral	1,78	deleterious	-7,4	deleterious	-4,8	high_impact	5,27	neutral	0,79	damaging	0,03	deleterious	2,38	18,66	0,03	0,35	disease	0,76	disease	0,92	disease	0,84	disease	0,77	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,92	low_impact	-3,53	medium_impact	0,06	high_impact	3,59	0,38	0,8	58,42	8,46	P	0,68	P	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15762	15762	G	A	MI.10491	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1016	339	G	E	gGa/gAa	8,88	1	0	probably_damaging	1	neutral	0,28	neutral	1,79	deleterious	-6,83	deleterious	-4,8	high_impact	4,72	neutral	0,72	damaging	0,04	deleterious	2,34	18,41	0,04	0,35	disease	0,7	disease	0,9	disease	0,84	disease	0,77	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0	high_impact	3,09	0,16	0,8	58,42	8,46	P	0,77	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	G15762A	MM	-	+	Reported	1
chrM	15762	15762	G	T	MI.10492	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1016	339	G	V	gGa/gTa	8,88	1	0	probably_damaging	1	neutral	0,52	neutral	1,79	deleterious	-7,06	deleterious	-5,4	high_impact	4,92	neutral	0,81	damaging	0,06	deleterious	2,28	18,03	0,04	0,35	disease	0,81	disease	0,91	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,24	high_impact	3,27	0,11	0,8	58,42	8,46	P	0,74	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15762	15762	G	C	MI.10493	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1016	339	G	A	gGa/gCa	8,88	1	0	probably_damaging	1	neutral	0,52	neutral	2	deleterious	-3,23	deleterious	-3,6	high_impact	3,88	neutral	0,86	damaging	0,07	neutral	1,59	13,82	0,06	0,35	disease	0,51	disease	0,78	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,24	high_impact	2,33	0,28	0,8	58,42	8,46	N	0,54	P	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15764	15764	G	C	MI.10494	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1018	340	G	R	Gga/Cga	-2,12	0	0	probably_damaging	1	neutral	0,34	neutral	3,07	neutral	-0,31	deleterious	-3,54	medium_impact	3,43	neutral	0,83	damaging	0,04	deleterious	2,46	19,22	0,05	0,35	disease	0,54	disease	0,93	disease	0,63	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,88	low_impact	-3,53	medium_impact	0,07	medium_impact	1,92	0,57	0,8	21,58	36,37	N	0,24	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15764	15764	G	T	MI.10495	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1018	340	G	W	Gga/Tga	-2,12	0	0	probably_damaging	1	neutral	0,19	neutral	3,04	deleterious	-3,94	deleterious	-3,9	high_impact	4,41	neutral	0,84	damaging	0,05	deleterious	2,98	22,2	0,05	0,35	disease	0,88	disease	0,93	disease	0,63	disease	0,78	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,12	high_impact	2,81	0,12	0,8	21,58	36,37	N	0,4	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15765	15765	G	C	MI.10496	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1019	340	G	A	gGa/gCa	3,38	1	0	probably_damaging	1	neutral	0,51	neutral	3,23	neutral	0,74	neutral	-2,24	low_impact	1,37	neutral	0,92	damaging	0,24	neutral	1,53	13,47	0,13	0,4	neutral	0,31	disease	0,7	neutral	0,25	neutral	0,46	1	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,78	low_impact	-3,53	medium_impact	0,23	medium_impact	0,05	0,34	0,8	21,58	36,37	N	0,37	N	0,74	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15765	15765	G	T	MI.10497	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1019	340	G	V	gGa/gTa	3,38	1	0	probably_damaging	1	neutral	0,52	neutral	3,12	neutral	-0,32	deleterious	-4,06	medium_impact	2,74	neutral	0,84	damaging	0,08	deleterious	2,24	17,8	0,04	0,35	neutral	0,48	disease	0,92	disease	0,58	disease	0,71	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,85	low_impact	-3,53	medium_impact	0,24	medium_impact	1,29	0,12	0,8	21,58	36,37	N	0,31	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15765	15765	G	A	MI.10498	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1019	340	G	E	gGa/gAa	3,38	1	0	probably_damaging	1	neutral	0,28	neutral	3,07	neutral	0,34	deleterious	-3,42	high_impact	3,86	neutral	0,82	damaging	0,07	deleterious	2,38	18,7	0,06	0,35	neutral	0,46	disease	0,92	disease	0,62	disease	0,73	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0	high_impact	2,31	0,23	0,8	21,58	36,37	N	0,38	N	0,95	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15767	15767	C	A	MI.10499	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1021	341	Q	K	Caa/Aaa	-5,79	0	0	probably_damaging	0,98	neutral	0,92	neutral	3,16	neutral	-0,13	neutral	-1,64	low_impact	1,85	neutral	0,93	neutral	0,35	deleterious	2,44	19,06	0,24	0,45	neutral	0,41	disease	0,88	neutral	0,46	disease	0,53	1	deleterious	0,98	deleterious	0,47	neutral	-2	deleterious	0,8	low_impact	-2,31	medium_impact	0,8	medium_impact	0,49	0,2	0,8	45,79	7,95	N	0,19	N	0,92	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	8573	8573	G	A	MI.105	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	47	16	G	D	gGc/gAc	6,14	1	0	benign	0,04	deleterious	0,04	neutral	4,6	neutral	-0,89	deleterious	-5,42	high_impact	3,67	neutral	0,92	neutral	0,34	neutral	1,71	14,49	0,17	0,65	disease	0,8	disease	0,91	disease	0,7	disease	0,8	6	neutral	0,96	deleterious	0,5	deleterious	2	neutral	0,33	medium_impact	0,55	medium_impact	-0,49	high_impact	2,05	0,57	0,9	17,26	11,64	P	0,54	P	0,91	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9019	9019	A	T	MI.1050	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	493	165	T	S	Act/Tct	-9,59	0	0	probably_damaging	0,99	neutral	0,34	neutral	4,26	neutral	-1,69	deleterious	-3,6	medium_impact	2	damaging	0,58	neutral	0,67	deleterious	3,38	23	0,44	0,65	disease	0,69	disease	0,74	disease	0,61	disease	0,57	1	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-2,65	medium_impact	0,13	medium_impact	0,62	0,72	0,9	48,67	8,72	N	0,29	N	0,88	polymorphism	0,96	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15767	15767	C	G	MI.10500	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1021	341	Q	E	Caa/Gaa	-5,79	0	0	probably_damaging	0,96	neutral	1	neutral	3,05	neutral	-1,73	neutral	-1,49	medium_impact	3,1	neutral	0,92	neutral	0,44	neutral	1,6	13,83	0,33	0,5	neutral	0,42	disease	0,87	neutral	0,5	disease	0,64	3	neutral	0,96	deleterious	0,52	deleterious	1	deleterious	0,79	low_impact	-2,02	high_impact	1,85	medium_impact	1,62	0,34	0,8	45,79	7,95	N	0,19	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15768	15768	A	G	MI.10501	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1022	341	Q	R	cAa/cGa	1,54	0,86	0	probably_damaging	0,99	neutral	0,52	neutral	3,09	neutral	-1,03	neutral	-1,6	medium_impact	2,25	neutral	0,93	neutral	0,39	deleterious	1,88	15,45	0,26	0,45	neutral	0,44	disease	0,89	neutral	0,45	disease	0,52	0	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,82	low_impact	-2,59	medium_impact	0,24	medium_impact	0,85	0,17	0,8	45,79	7,95	N	0,28	N	0,8	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15768	15768	A	T	MI.10502	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1022	341	Q	L	cAa/cTa	1,54	0,86	0	probably_damaging	0,98	neutral	0,32	neutral	3,16	neutral	-0,13	neutral	-2,27	medium_impact	2,33	neutral	0,94	neutral	0,38	deleterious	2,16	17,26	0,11	0,4	neutral	0,35	disease	0,91	disease	0,51	disease	0,51	0	deleterious	0,98	neutral	0,17	deleterious	1	deleterious	0,8	low_impact	-2,31	medium_impact	0,05	medium_impact	0,92	0,09	0,8	45,79	7,95	N	0,35	N	0,89	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15768	15768	A	C	MI.10503	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1022	341	Q	P	cAa/cCa	1,54	0,86	0	probably_damaging	1	neutral	0,28	neutral	3,04	neutral	-2,29	deleterious	-2,67	high_impact	4,05	neutral	0,91	neutral	0,29	neutral	1,76	14,73	0,08	0,35	disease	0,66	disease	0,95	disease	0,62	disease	0,79	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0	high_impact	2,48	0,18	0,8	45,79	7,95	N	0,37	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15769	15769	A	T	MI.10504	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1023	341	Q	H	caA/caT	4,98	0,99	0,01	probably_damaging	1	neutral	0,13	neutral	3,03	neutral	-2,49	neutral	-2,25	high_impact	3,62	neutral	0,9	neutral	0,31	deleterious	2,52	19,58	0,18	0,45	disease	0,63	disease	0,85	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,23	high_impact	2,09	0,26	0,8	45,79	7,95	P	0,59	P	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15769	15769	A	C	MI.10505	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1023	341	Q	H	caA/caC	4,98	0,99	0,01	probably_damaging	1	neutral	0,13	neutral	3,03	neutral	-2,49	neutral	-2,25	high_impact	3,62	neutral	0,9	neutral	0,31	deleterious	2,36	18,55	0,18	0,45	disease	0,63	disease	0,85	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,23	high_impact	2,09	0,26	0,8	45,79	7,95	P	0,58	P	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15770	15770	C	T	MI.10506	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1024	342	P	S	Cca/Tca	0,17	0,97	0	probably_damaging	1	neutral	0,6	neutral	2,92	neutral	-2,32	deleterious	-4,68	high_impact	3,52	neutral	0,93	neutral	0,47	deleterious	2,35	18,47	0,18	0,45	neutral	0,4	disease	0,86	disease	0,68	disease	0,72	4	deleterious	0,99	neutral	0,3	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,32	high_impact	2	0,12	0,8	56,84	8,43	N	0,37	N	0,9	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15770	15770	C	A	MI.10507	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1024	342	P	T	Cca/Aca	0,17	0,97	0	probably_damaging	1	neutral	0,51	neutral	2,93	neutral	-2,04	deleterious	-4,69	high_impact	4,21	neutral	0,91	neutral	0,43	deleterious	2,32	18,3	0,14	0,4	neutral	0,37	disease	0,86	disease	0,66	disease	0,72	4	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,23	high_impact	2,63	0,43	0,8	56,84	8,43	N	0,47	N	0,96	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15770	15770	C	G	MI.10508	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1024	342	P	A	Cca/Gca	0,17	0,97	0	probably_damaging	0,98	neutral	0,68	neutral	2,93	neutral	-2,02	deleterious	-4,67	high_impact	3,56	neutral	0,94	neutral	0,49	neutral	1,56	13,65	0,17	0,45	neutral	0,4	disease	0,78	disease	0,63	disease	0,67	3	neutral	0,97	neutral	0,35	deleterious	2	deleterious	0,76	low_impact	-2,31	medium_impact	0,4	high_impact	2,04	0,65	0,8	56,84	8,43	N	0,34	N	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15771	15771	C	T	MI.10509	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1025	342	P	L	cCa/cTa	5,44	1	0	probably_damaging	1	neutral	0,74	neutral	3,01	neutral	-1,1	deleterious	-5,86	high_impact	3,56	neutral	0,93	neutral	0,38	deleterious	2,84	21,6	0,08	0,35	neutral	0,41	disease	0,91	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,47	high_impact	2,04	0,54	0,8	56,84	8,43	N	0,45	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9019	9019	A	G	MI.1051	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	493	165	T	A	Act/Gct	-9,59	0	0	probably_damaging	0,99	neutral	0,08	neutral	4,29	neutral	-1,1	deleterious	-4,49	high_impact	3,56	neutral	0,67	neutral	0,63	deleterious	3,57	23,1	0,53	0,65	neutral	0,45	disease	0,72	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,74	low_impact	-2,65	medium_impact	-0,31	medium_impact	1,95	0,68	0,9	48,67	8,72	N	0,41	N	0,63	polymorphism	0,88	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15771	15771	C	G	MI.10510	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1025	342	P	R	cCa/cGa	5,44	1	0	probably_damaging	1	neutral	0,48	neutral	2,9	neutral	-2,71	deleterious	-5,28	high_impact	5,11	neutral	0,93	neutral	0,35	deleterious	2,09	16,78	0,08	0,35	neutral	0,42	disease	0,93	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,2	high_impact	3,45	0,23	0,8	56,84	8,43	P	0,69	P	0,8	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15771	15771	C	A	MI.10511	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1025	342	P	Q	cCa/cAa	5,44	1	0	probably_damaging	1	neutral	0,49	neutral	2,91	neutral	-2,51	deleterious	-4,69	high_impact	3,6	neutral	0,92	neutral	0,38	deleterious	2,63	20,4	0,12	0,4	neutral	0,41	disease	0,87	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,21	high_impact	2,08	0,32	0,8	56,84	8,43	N	0,52	P	0,86	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15773	15773	G	A	MI.10512	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1027	343	V	M	Gta/Ata	-3,73	0	0,01	probably_damaging	1	neutral	0,24	neutral	2,84	deleterious	-3,53	neutral	-1,72	high_impact	3,84	neutral	0,67	neutral	0,45	deleterious	2,2	17,51	0,21	0,45	disease	0,6	disease	0,78	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,74	low_impact	-3,53	medium_impact	-0,05	high_impact	2,29	0,83	0,9	44,74	7,85	N	0,38	N	0,97	polymorphism	1	0,03	rs386829261	.	.	.	.	.	.	.	.	G15773A	LHON	+	-	Possibly synergistic	1
chrM	15773	15773	G	C	MI.10513	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1027	343	V	L	Gta/Cta	-3,73	0	0,01	possibly_damaging	0,87	neutral	0,68	neutral	2,93	neutral	-1,62	neutral	-1,74	high_impact	3,68	neutral	0,82	neutral	0,41	deleterious	2,13	17,06	0,17	0,45	neutral	0,42	disease	0,79	disease	0,58	disease	0,66	3	neutral	0,85	neutral	0,41	deleterious	1	deleterious	0,62	low_impact	-1,5	medium_impact	0,4	high_impact	2,15	0,41	0,8	44,74	7,85	N	0,24	N	0,69	polymorphism	1	0,02	rs386829261	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15773	15773	G	T	MI.10514	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1027	343	V	L	Gta/Tta	-3,73	0	0,01	possibly_damaging	0,87	neutral	0,68	neutral	2,93	neutral	-1,62	neutral	-1,74	high_impact	3,68	neutral	0,82	neutral	0,41	deleterious	2,22	17,65	0,17	0,45	neutral	0,42	disease	0,79	disease	0,58	disease	0,66	3	neutral	0,85	neutral	0,41	deleterious	1	deleterious	0,62	low_impact	-1,5	medium_impact	0,4	high_impact	2,15	0,41	0,8	44,74	7,85	N	0,24	N	0,69	polymorphism	1	0,02	rs386829261	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15774	15774	T	A	MI.10515	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1028	343	V	E	gTa/gAa	5,9	1	0	probably_damaging	0,99	neutral	0,36	neutral	2,84	deleterious	-3,33	deleterious	-3,49	high_impact	4,88	neutral	0,8	neutral	0,41	deleterious	3,24	22,8	0,03	0,35	neutral	0,29	disease	0,9	disease	0,71	disease	0,75	5	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	0,09	high_impact	3,24	0,2	0,8	44,74	7,85	P	0,68	P	1	polymorphism	1	0,15	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15774	15774	T	G	MI.10516	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1028	343	V	G	gTa/gGa	5,9	1	0	probably_damaging	1	neutral	0,38	neutral	2,83	deleterious	-3,79	deleterious	-4,07	high_impact	4,18	neutral	0,81	neutral	0,47	deleterious	2,3	18,18	0,04	0,35	disease	0,64	disease	0,79	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	0,11	high_impact	2,6	0,16	0,8	44,74	7,85	P	0,56	P	0,96	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15774	15774	T	C	MI.10517	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1028	343	V	A	gTa/gCa	5,9	1	0	probably_damaging	0,99	neutral	0,56	neutral	2,93	neutral	-1,65	neutral	-2,3	medium_impact	2,22	neutral	0,78	neutral	0,51	deleterious	2,09	16,78	0,16	0,45	neutral	0,38	disease	0,67	neutral	0,49	neutral	0,44	1	deleterious	0,98	neutral	0,29	deleterious	1	deleterious	0,72	low_impact	-2,59	medium_impact	0,28	medium_impact	0,82	0,21	0,8	44,74	7,85	N	0,36	N	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15776	15776	A	G	MI.10518	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1030	344	S	G	Agc/Ggc	-10,15	0	0	benign	0,4	neutral	0,39	neutral	3,17	neutral	0,04	neutral	-1,29	low_impact	0,84	neutral	0,93	neutral	0,58	deleterious	2,09	16,81	0,35	0,5	neutral	0,39	disease	0,51	neutral	0,4	neutral	0,46	1	neutral	0,55	deleterious	0,5	neutral	-6	neutral	0,37	medium_impact	-0,57	medium_impact	0,12	medium_impact	-0,43	0,4	0,8	22,37	48,43	N	0,33	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15776	15776	A	T	MI.10519	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1030	344	S	C	Agc/Tgc	-10,15	0	0	probably_damaging	0,96	neutral	0,18	neutral	3,08	deleterious	-3,75	neutral	-2,39	low_impact	1,73	neutral	0,95	neutral	0,44	deleterious	1,91	15,67	0,1	0,4	disease	0,75	disease	0,74	neutral	0,39	disease	0,52	0	neutral	0,98	neutral	0,11	neutral	-2	deleterious	0,8	low_impact	-2,02	medium_impact	-0,14	medium_impact	0,38	0,12	0,8	22,37	48,43	N	0,35	N	0,69	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9020	9020	C	T	MI.1052	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	494	165	T	I	aCt/aTt	8,69	1	0	probably_damaging	1	neutral	0,54	neutral	4,36	neutral	-0,2	deleterious	-5,43	low_impact	1,74	damaging	0,56	neutral	0,63	deleterious	4	23,6	0,39	0,65	neutral	0,44	disease	0,68	neutral	0,47	neutral	0,46	1	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,33	medium_impact	0,39	0,71	0,9	48,67	8,72	N	0,45	N	0,97	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15776	15776	A	C	MI.10520	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1030	344	S	R	Agc/Cgc	-10,15	0	0	possibly_damaging	0,66	neutral	0,41	neutral	3,14	neutral	-0,52	neutral	-0,3	low_impact	1,18	neutral	0,95	neutral	0,53	deleterious	2,33	18,37	0,15	0,4	neutral	0,28	disease	0,88	neutral	0,49	disease	0,75	5	neutral	0,67	neutral	0,38	neutral	-3	deleterious	0,6	medium_impact	-1	medium_impact	0,14	medium_impact	-0,12	0,24	0,8	22,37	48,43	N	0,31	N	0,53	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15777	15777	G	T	MI.10521	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1031	344	S	I	aGc/aTc	4,98	1	0	possibly_damaging	0,89	neutral	0,46	neutral	3,09	neutral	-2,55	neutral	-1,9	medium_impact	2,08	neutral	0,94	neutral	0,67	deleterious	2,59	20,1	0,1	0,4	neutral	0,44	disease	0,78	neutral	0,41	disease	0,64	3	neutral	0,88	neutral	0,29	NA	0	deleterious	0,73	low_impact	-1,58	medium_impact	0,18	medium_impact	0,7	0,19	0,8	22,37	48,43	N	0,48	N	0,66	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15777	15777	G	A	MI.10522	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1031	344	S	N	aGc/aAc	4,98	1	0	benign	0,03	neutral	0,34	neutral	3,15	neutral	-0,33	neutral	-0,17	neutral_impact	0,58	neutral	0,9	neutral	0,79	deleterious	2,13	17,05	0,56	0,6	neutral	0,2	disease	0,73	neutral	0,3	disease	0,54	1	neutral	0,64	deleterious	0,66	neutral	-6	neutral	0,19	medium_impact	0,68	medium_impact	0,07	medium_impact	-0,67	0,29	0,8	22,37	48,43	N	0,52	P	0,37	polymorphism	1	0,01	rs879182710	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15777	15777	G	C	MI.10523	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1031	344	S	T	aGc/aCc	4,98	1	0	benign	0,4	neutral	0,45	neutral	3,17	neutral	0,04	neutral	-0,67	neutral_impact	-0,5	neutral	0,92	neutral	0,63	deleterious	1,88	15,48	0,45	0,55	neutral	0,19	neutral	0,46	neutral	0,25	neutral	0,44	1	neutral	0,49	deleterious	0,53	neutral	-6	neutral	0,4	medium_impact	-0,57	medium_impact	0,18	low_impact	-1,65	0,34	0,8	22,37	48,43	N	0,48	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15779	15779	T	G	MI.10524	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1033	345	Y	D	Tac/Gac	2	0,99	0	possibly_damaging	0,86	neutral	0,22	neutral	3	neutral	-0,02	neutral	-1,19	neutral_impact	-0,02	neutral	0,94	neutral	0,42	neutral	1,28	12,17	0,1	0,4	neutral	0,16	neutral	0,5	neutral	0,28	neutral	0,4	2	neutral	0,91	neutral	0,18	neutral	-3	deleterious	0,63	low_impact	-1,47	medium_impact	-0,08	low_impact	-1,21	0,23	0,8	23,95	30,35	N	0,43	N	0,64	disease_causing	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15779	15779	T	C	MI.10525	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1033	345	Y	H	Tac/Cac	2	0,99	0	benign	0,05	neutral	0,55	neutral	2,95	neutral	-1,35	neutral	1,74	neutral_impact	-0,18	neutral	0,94	neutral	0,98	neutral	-0,63	0,11	0,24	0,45	neutral	0,16	neutral	0,07	neutral	0,19	neutral	0,28	4	neutral	0,39	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	0,46	medium_impact	0,27	low_impact	-1,36	0,23	0,8	23,95	30,35	N	0,43	N	0,04	polymorphism	1	0,01	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15779	15779	T	A	MI.10526	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1033	345	Y	N	Tac/Aac	2	0,99	0	possibly_damaging	0,76	neutral	0,32	neutral	2,98	neutral	-0,28	neutral	-0,68	low_impact	1,21	neutral	0,92	neutral	0,84	neutral	1,39	12,73	0,12	0,4	neutral	0,19	disease	0,65	neutral	0,31	neutral	0,44	1	neutral	0,8	neutral	0,28	neutral	-3	deleterious	0,53	low_impact	-1,2	medium_impact	0,05	medium_impact	-0,1	0,23	0,8	23,95	30,35	N	0,47	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15780	15780	A	G	MI.10527	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1034	345	Y	C	tAc/tGc	0,17	0,98	0	probably_damaging	0,98	neutral	0,18	neutral	2,92	deleterious	-3,27	neutral	-2,41	medium_impact	3,35	neutral	0,93	neutral	0,38	deleterious	2,54	19,75	0,11	0,4	neutral	0,28	disease	0,78	neutral	0,33	disease	0,6	2	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,69	low_impact	-2,31	medium_impact	-0,14	medium_impact	1,85	0,08	0,8	23,95	30,35	N	0,5	N	0,67	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15780	15780	A	T	MI.10528	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1034	345	Y	F	tAc/tTc	0,17	0,98	0	possibly_damaging	0,68	neutral	0,71	neutral	2,94	neutral	-1,86	neutral	-1,45	medium_impact	2	neutral	0,93	neutral	0,6	deleterious	2,43	19,02	0,27	0,45	neutral	0,48	disease	0,61	neutral	0,35	neutral	0,49	0	neutral	0,62	deleterious	0,52	NA	0	deleterious	0,61	low_impact	-1,04	medium_impact	0,43	medium_impact	0,62	0,19	0,8	23,95	30,35	N	0,33	N	0,44	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15780	15780	A	C	MI.10529	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1034	345	Y	S	tAc/tCc	0,17	0,98	0	possibly_damaging	0,82	neutral	0,43	neutral	3,02	neutral	0,32	neutral	-1,25	low_impact	1,32	neutral	0,94	neutral	0,75	deleterious	2,64	20,4	0,1	0,4	neutral	0,16	disease	0,57	neutral	0,3	neutral	0,42	2	neutral	0,81	neutral	0,31	neutral	-3	deleterious	0,58	low_impact	-1,35	medium_impact	0,16	medium_impact	0,01	0,15	0,8	23,95	30,35	N	0,36	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9020	9020	C	G	MI.1053	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	494	165	T	S	aCt/aGt	8,69	1	0	probably_damaging	0,99	neutral	0,34	neutral	4,26	neutral	-1,69	deleterious	-3,6	medium_impact	2	damaging	0,58	neutral	0,67	deleterious	3,59	23,2	0,44	0,65	disease	0,69	disease	0,74	disease	0,61	disease	0,57	1	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-2,65	medium_impact	0,13	medium_impact	0,62	0,72	0,9	48,67	8,72	P	0,51	P	0,88	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15782	15782	C	A	MI.10530	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1036	346	P	T	Cct/Act	-0,29	0,67	0	probably_damaging	1	neutral	0,72	neutral	2,84	neutral	-2,63	deleterious	-4,7	medium_impact	3,11	neutral	0,82	damaging	0,08	deleterious	2,34	18,43	0,08	0,35	neutral	0,45	disease	0,86	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,83	low_impact	-3,53	medium_impact	0,44	medium_impact	1,63	0,4	0,8	55	8,32	N	0,2	N	0,96	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15782	15782	C	T	MI.10531	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1036	346	P	S	Cct/Tct	-0,29	0,67	0	probably_damaging	1	neutral	0,81	neutral	2,83	neutral	-2,81	deleterious	-4,7	high_impact	4,35	neutral	0,84	damaging	0,07	deleterious	2,33	18,38	0,08	0,35	neutral	0,36	disease	0,86	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,41	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,56	high_impact	2,76	0,08	0,8	55	8,32	N	0,33	N	0,9	polymorphism	1	0,09	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15782	15782	C	G	MI.10532	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1036	346	P	A	Cct/Gct	-0,29	0,67	0	probably_damaging	0,99	neutral	0,93	neutral	2,87	neutral	-2,2	deleterious	-4,7	high_impact	3,66	neutral	0,87	damaging	0,11	neutral	1,56	13,61	0,1	0,4	neutral	0,4	disease	0,77	disease	0,71	disease	0,71	4	deleterious	0,99	deleterious	0,47	deleterious	2	deleterious	0,78	low_impact	-2,59	medium_impact	0,83	high_impact	2,13	0,64	0,8	55	8,32	N	0,26	N	0,84	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15783	15783	C	G	MI.10533	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1037	346	P	R	cCt/cGt	4,29	1	0	probably_damaging	1	neutral	0,64	neutral	2,82	deleterious	-3,16	deleterious	-5,29	high_impact	4,5	neutral	0,82	damaging	0,05	deleterious	2,14	17,13	0,04	0,35	neutral	0,45	disease	0,91	disease	0,8	disease	0,78	6	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,36	high_impact	2,89	0,23	0,8	55	8,32	N	0,51	P	0,8	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15783	15783	C	T	MI.10534	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1037	346	P	L	cCt/cTt	4,29	1	0	probably_damaging	1	neutral	0,81	neutral	2,89	neutral	-1,85	deleterious	-5,88	medium_impact	3,29	neutral	0,85	damaging	0,05	deleterious	2,82	21,5	0,05	0,35	neutral	0,49	disease	0,88	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,41	deleterious	1	deleterious	0,83	low_impact	-3,53	medium_impact	0,56	medium_impact	1,79	0,67	0,85	55	8,32	N	0,35	N	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15783	15783	C	A	MI.10535	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1037	346	P	H	cCt/cAt	4,29	1	0	probably_damaging	1	neutral	0,59	neutral	2,8	deleterious	-3,86	deleterious	-5,29	high_impact	4,7	neutral	0,84	damaging	0,07	deleterious	2,51	19,51	0,05	0,35	disease	0,63	disease	0,88	disease	0,81	disease	0,77	5	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,31	high_impact	3,07	0,26	0,8	55	8,32	P	0,61	P	0,71	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15785	15785	T	C	MI.10536	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1039	347	F	L	Ttt/Ctt	-8,31	0	0	probably_damaging	1	neutral	0,65	neutral	3,07	neutral	-0,78	deleterious	-2,8	medium_impact	2,71	neutral	0,97	damaging	0,24	deleterious	2,47	19,29	0,18	0,45	neutral	0,45	disease	0,73	neutral	0,45	neutral	0,48	0	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,77	low_impact	-3,53	medium_impact	0,37	medium_impact	1,27	0,65	0,8	15,79	14,55	N	0,23	N	0,12	polymorphism	1	0,03	rs879052837	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15785	15785	T	A	MI.10537	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1039	347	F	I	Ttt/Att	-8,31	0	0	probably_damaging	1	neutral	0,4	neutral	3,03	neutral	-1,37	deleterious	-2,86	medium_impact	3,48	neutral	0,94	damaging	0,16	deleterious	2,89	21,8	0,11	0,4	disease	0,63	disease	0,79	disease	0,59	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,81	low_impact	-3,53	medium_impact	0,13	medium_impact	1,97	0,35	0,8	15,79	14,55	N	0,29	N	0,68	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15785	15785	T	G	MI.10538	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1039	347	F	V	Ttt/Gtt	-8,31	0	0	probably_damaging	1	neutral	0,5	neutral	3,02	neutral	-1,42	deleterious	-3,28	high_impact	3,68	neutral	0,95	damaging	0,16	deleterious	2,6	20,2	0,06	0,35	disease	0,59	disease	0,88	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,22	high_impact	2,15	0,17	0,8	15,79	14,55	N	0,32	N	0,76	polymorphism	1	0,04	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15786	15786	T	G	MI.10539	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1040	347	F	C	tTt/tGt	5,67	0,87	0	probably_damaging	1	neutral	0,18	neutral	2,95	deleterious	-3,95	deleterious	-3,9	high_impact	4,24	neutral	0,94	damaging	0,13	deleterious	2,58	19,96	0,03	0,35	disease	0,87	disease	0,87	disease	0,61	disease	0,78	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,14	high_impact	2,66	0,12	0,8	15,79	14,55	N	0,51	P	0,86	polymorphism	1	0,14	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	9020	9020	C	A	MI.1054	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	494	165	T	N	aCt/aAt	8,69	1	0	probably_damaging	1	deleterious	0	neutral	4,23	neutral	-2,94	deleterious	-4,54	high_impact	4,1	damaging	0,56	neutral	0,53	deleterious	3,67	23,3	0,36	0,65	disease	0,82	disease	0,86	disease	0,66	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,6	low_impact	-1,4	high_impact	2,42	0,75	0,9	48,67	8,72	P	0,5	N	0,9	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15786	15786	T	A	MI.10540	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1040	347	F	Y	tTt/tAt	5,67	0,87	0	probably_damaging	1	neutral	1	neutral	3,17	neutral	0,02	neutral	-0,55	neutral_impact	0,43	neutral	0,98	neutral	0,91	deleterious	0,77	9,29	0,15	0,4	neutral	0,32	neutral	0,25	neutral	0,22	neutral	0,44	1	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,72	low_impact	-3,53	high_impact	1,85	medium_impact	-0,8	0,56	0,8	15,79	14,55	N	0,44	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15786	15786	T	C	MI.10541	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1040	347	F	S	tTt/tCt	5,67	0,87	0	probably_damaging	1	neutral	0,4	neutral	2,98	neutral	-2,25	deleterious	-3,92	high_impact	4,24	neutral	0,93	damaging	0,13	deleterious	2,68	20,7	0,02	0,35	disease	0,65	disease	0,85	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,13	high_impact	2,66	0,09	0,8	15,79	14,55	N	0,52	P	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15787	15787	T	G	MI.10542	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1041	347	F	L	ttT/ttG	-0,06	0,01	0,01	probably_damaging	1	neutral	0,65	neutral	3,07	neutral	-0,78	deleterious	-2,8	medium_impact	2,71	neutral	0,97	damaging	0,24	deleterious	2,72	20,9	0,18	0,45	neutral	0,45	disease	0,73	neutral	0,45	neutral	0,48	0	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,77	low_impact	-3,53	medium_impact	0,37	medium_impact	1,27	0,65	0,8	15,79	14,55	N	0,24	N	0,12	polymorphism	1	0,03	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15787	15787	T	A	MI.10543	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1041	347	F	L	ttT/ttA	-0,06	0,01	0,01	probably_damaging	1	neutral	0,65	neutral	3,07	neutral	-0,78	deleterious	-2,8	medium_impact	2,71	neutral	0,97	damaging	0,24	deleterious	2,86	21,7	0,18	0,45	neutral	0,45	disease	0,73	neutral	0,45	neutral	0,48	0	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,77	low_impact	-3,53	medium_impact	0,37	medium_impact	1,27	0,65	0,8	15,79	14,55	N	0,25	N	0,12	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15788	15788	A	G	MI.10544	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1042	348	T	A	Acc/Gcc	-2,35	0	0	benign	0,12	neutral	0,48	neutral	3,12	neutral	-0,65	neutral	-0,4	medium_impact	2,01	neutral	0,94	neutral	0,75	deleterious	2	16,22	0,23	0,45	neutral	0,29	neutral	0,48	disease	0,51	disease	0,5	0	neutral	0,44	deleterious	0,68	neutral	-3	neutral	0,16	medium_impact	0,08	medium_impact	0,2	medium_impact	0,63	0,35	0,8	17,37	14,81	N	0,32	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15788	15788	A	C	MI.10545	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1042	348	T	P	Acc/Ccc	-2,35	0	0	possibly_damaging	0,71	neutral	0,26	neutral	3,07	neutral	-1,97	neutral	-1,48	medium_impact	2,73	neutral	0,94	neutral	0,45	deleterious	1,99	16,12	0,04	0,35	disease	0,61	disease	0,84	disease	0,65	disease	0,8	6	neutral	0,8	neutral	0,28	NA	0	deleterious	0,56	low_impact	-1,09	medium_impact	-0,02	medium_impact	1,29	0,34	0,8	17,37	14,81	N	0,32	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15788	15788	A	T	MI.10546	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1042	348	T	S	Acc/Tcc	-2,35	0	0	benign	0,37	neutral	0,36	neutral	3,12	neutral	-0,79	neutral	-0,85	low_impact	1,51	neutral	0,94	neutral	0,63	neutral	1,8	14,97	0,31	0,45	neutral	0,28	disease	0,53	neutral	0,47	neutral	0,5	0	neutral	0,58	deleterious	0,5	neutral	-6	neutral	0,24	medium_impact	-0,52	medium_impact	0,09	medium_impact	0,18	0,68	0,85	17,37	14,81	N	0,35	N	0,19	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15789	15789	C	G	MI.10547	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1043	348	T	S	aCc/aGc	2,46	0,87	0	benign	0,37	neutral	0,36	neutral	3,12	neutral	-0,79	neutral	-0,85	low_impact	1,51	neutral	0,94	neutral	0,63	deleterious	2,02	16,32	0,31	0,45	neutral	0,28	disease	0,53	neutral	0,47	neutral	0,5	0	neutral	0,58	deleterious	0,5	neutral	-6	neutral	0,24	medium_impact	-0,52	medium_impact	0,09	medium_impact	0,18	0,68	0,85	17,37	14,81	N	0,36	N	0,19	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15789	15789	C	T	MI.10548	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1043	348	T	I	aCc/aTc	2,46	0,87	0	benign	0,01	neutral	0,55	neutral	3,31	neutral	1,14	neutral	1,92	neutral_impact	-1,16	neutral	0,95	neutral	0,96	neutral	-0,26	0,82	0,12	0,4	neutral	0,16	neutral	0,1	neutral	0,17	neutral	0,28	4	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,08	medium_impact	1,13	medium_impact	0,27	low_impact	-2,25	0,68	0,85	17,37	14,81	N	0,3	N	0,03	polymorphism	1	0,01	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15789	15789	C	A	MI.10549	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1043	348	T	N	aCc/aAc	2,46	0,87	0	possibly_damaging	0,59	neutral	0,25	neutral	3,09	neutral	-1,53	neutral	-1,44	low_impact	1,69	neutral	0,91	neutral	0,66	deleterious	2,13	17,08	0,24	0,45	neutral	0,31	disease	0,74	disease	0,52	disease	0,61	2	neutral	0,75	neutral	0,33	neutral	-3	neutral	0,42	medium_impact	-0,88	medium_impact	-0,04	medium_impact	0,34	0,54	0,8	17,37	14,81	N	0,38	N	0,38	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	9022	9022	G	A	MI.1055	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	496	166	A	T	Gca/Aca	-7,74	0	0	probably_damaging	1	deleterious	0,02	neutral	3,3	deleterious	-5,88	deleterious	-3,54	high_impact	3,74	damaging	0,57	neutral	0,46	deleterious	4,27	24	0,31	0,65	disease	0,9	disease	0,88	disease	0,7	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-3,6	medium_impact	-0,66	high_impact	2,11	0,71	0,9	49,56	8,89	N	0,32	N	0,8	disease_causing	0,99	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15791	15791	A	G	MI.10550	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1045	349	I	V	Atc/Gtc	-4,87	0	0	benign	0,01	neutral	0,51	neutral	3,11	neutral	-0,15	neutral	-0,24	low_impact	1,49	neutral	0,97	neutral	0,87	deleterious	0,48	7,31	0,44	0,55	neutral	0,27	neutral	0,41	neutral	0,42	neutral	0,44	1	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,12	medium_impact	1,13	medium_impact	0,23	medium_impact	0,16	0,33	0,8	20	24,59	N	0,3	N	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15791	15791	A	C	MI.10551	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1045	349	I	L	Atc/Ctc	-4,87	0	0	benign	0,03	neutral	0,63	neutral	3,23	neutral	0,28	neutral	-0,56	neutral_impact	0,78	neutral	0,96	neutral	0,79	neutral	1,08	11,09	0,22	0,45	neutral	0,24	neutral	0,46	neutral	0,3	neutral	0,45	1	neutral	0,33	deleterious	0,8	neutral	-6	neutral	0,14	medium_impact	0,68	medium_impact	0,35	medium_impact	-0,49	0,69	0,85	20	24,59	N	0,3	N	0,59	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15791	15791	A	T	MI.10552	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1045	349	I	F	Atc/Ttc	-4,87	0	0	benign	0,23	neutral	0,62	neutral	3,09	neutral	-1,11	neutral	-1,62	low_impact	1,75	neutral	0,97	neutral	0,47	deleterious	2,42	18,96	0,19	0,45	neutral	0,44	disease	0,8	neutral	0,42	disease	0,54	1	neutral	0,27	deleterious	0,7	neutral	-6	neutral	0,27	medium_impact	-0,24	medium_impact	0,34	medium_impact	0,4	0,68	0,85	20	24,59	N	0,21	N	0,69	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15792	15792	T	C	MI.10553	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1046	349	I	T	aTc/aCc	1,54	0	0	benign	0	neutral	0,34	neutral	3,13	neutral	-0,64	neutral	-1,33	neutral_impact	0,66	neutral	0,99	neutral	0,93	deleterious	0,36	6,3	0,11	0,4	neutral	0,28	disease	0,55	neutral	0,41	neutral	0,44	1	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,16	high_impact	2,07	medium_impact	0,07	medium_impact	-0,59	0,3	0,8	20	24,59	N	0,42	N	0,03	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15792	15792	T	G	MI.10554	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1046	349	I	S	aTc/aGc	1,54	0	0	benign	0,06	neutral	0,32	neutral	3,08	neutral	-1,2	neutral	-2,09	low_impact	1,91	neutral	0,97	neutral	0,6	deleterious	2,78	21,2	0,03	0,35	disease	0,58	disease	0,85	disease	0,57	disease	0,65	3	neutral	0,65	deleterious	0,63	neutral	-6	neutral	0,27	medium_impact	0,38	medium_impact	0,05	medium_impact	0,54	0,31	0,8	20	24,59	N	0,31	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15792	15792	T	A	MI.10555	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1046	349	I	N	aTc/aAc	1,54	0	0	benign	0,13	neutral	0,21	neutral	3,05	neutral	-2,26	deleterious	-2,63	medium_impact	2,49	neutral	0,93	neutral	0,45	deleterious	2,92	21,9	0,08	0,35	disease	0,74	disease	0,85	disease	0,57	disease	0,69	4	neutral	0,76	deleterious	0,54	neutral	-3	neutral	0,31	medium_impact	0,04	medium_impact	-0,09	medium_impact	1,07	0,2	0,8	20	24,59	N	0,35	N	0,62	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15793	15793	C	G	MI.10556	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1047	349	I	M	atC/atG	0,17	0	0,01	possibly_damaging	0,45	neutral	0,24	neutral	3,07	neutral	-1,35	neutral	-0,94	low_impact	1,46	neutral	0,95	neutral	0,85	deleterious	0,73	9,03	0,27	0,45	disease	0,54	neutral	0,47	neutral	0,39	disease	0,59	2	neutral	0,73	neutral	0,4	neutral	-3	neutral	0,25	medium_impact	-0,65	medium_impact	-0,05	medium_impact	0,13	0,69	0,85	20	24,59	N	0,42	N	0,68	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15793	15793	C	A	MI.10557	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1047	349	I	M	atC/atA	0,17	0	0,01	possibly_damaging	0,45	neutral	0,24	neutral	3,07	neutral	-1,35	neutral	-0,94	low_impact	1,46	neutral	0,95	neutral	0,85	neutral	1,26	12,04	0,27	0,45	disease	0,54	neutral	0,47	neutral	0,39	disease	0,59	2	neutral	0,73	neutral	0,4	neutral	-3	neutral	0,25	medium_impact	-0,65	medium_impact	-0,05	medium_impact	0,13	0,69	0,85	20	24,59	N	0,42	N	0,68	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15794	15794	A	T	MI.10558	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1048	350	I	F	Att/Ttt	-7,62	0	0	probably_damaging	1	neutral	0,85	neutral	2,89	neutral	-1,09	neutral	-2,16	medium_impact	3,29	neutral	0,95	neutral	0,37	deleterious	2,23	17,68	0,11	0,4	neutral	0,49	disease	0,89	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,43	deleterious	1	deleterious	0,81	low_impact	-3,53	medium_impact	0,63	medium_impact	1,79	0,57	0,8	42,11	12,09	N	0,3	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15794	15794	A	C	MI.10559	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1048	350	I	L	Att/Ctt	-7,62	0	0	probably_damaging	0,97	neutral	0,85	neutral	3,06	neutral	0,39	neutral	-1,03	low_impact	1,66	neutral	0,94	neutral	0,35	deleterious	2,31	18,22	0,31	0,45	neutral	0,24	disease	0,69	disease	0,52	neutral	0,47	1	neutral	0,97	neutral	0,44	neutral	-2	deleterious	0,56	low_impact	-2,14	medium_impact	0,63	medium_impact	0,31	0,65	0,8	42,11	12,09	N	0,22	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9022	9022	G	T	MI.1056	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	496	166	A	S	Gca/Tca	-7,74	0	0	probably_damaging	0,99	neutral	0,09	neutral	3,45	deleterious	-3,49	deleterious	-2,65	medium_impact	2,56	damaging	0,53	neutral	0,58	deleterious	3,78	23,4	0,24	0,65	disease	0,74	disease	0,88	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,87	low_impact	-2,65	medium_impact	-0,28	medium_impact	1,1	0,76	0,9	49,56	8,89	N	0,32	N	0,95	disease_causing	0,98	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15794	15794	A	G	MI.10560	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1048	350	I	V	Att/Gtt	-7,62	0	0	probably_damaging	0,93	neutral	0,52	neutral	3	neutral	0	neutral	-0,51	medium_impact	2,06	neutral	0,98	neutral	0,65	neutral	1,52	13,43	0,5	0,6	neutral	0,27	disease	0,56	disease	0,58	neutral	0,44	1	neutral	0,92	neutral	0,3	deleterious	1	deleterious	0,55	low_impact	-1,78	medium_impact	0,24	medium_impact	0,68	0,59	0,8	42,11	12,09	N	0,34	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15795	15795	T	G	MI.10561	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1049	350	I	S	aTt/aGt	6,81	1	0	probably_damaging	1	neutral	0,39	neutral	2,84	neutral	-1,93	deleterious	-3,19	high_impact	4,09	neutral	0,94	neutral	0,39	deleterious	2,75	21,1	0,03	0,35	neutral	0,48	disease	0,9	disease	0,76	disease	0,8	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,12	high_impact	2,52	0,25	0,8	42,11	12,09	P	0,59	P	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15795	15795	T	A	MI.10562	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1049	350	I	N	aTt/aAt	6,81	1	0	probably_damaging	1	neutral	0,29	neutral	2,81	deleterious	-3,14	deleterious	-3,75	high_impact	4,79	neutral	0,93	neutral	0,37	deleterious	2,86	21,7	0,07	0,35	disease	0,66	disease	0,89	disease	0,77	disease	0,81	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,01	high_impact	3,16	0,38	0,8	42,11	12,09	P	0,76	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15795	15795	T	C	MI.10563	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1049	350	I	T	aTt/aCt	6,81	1	0	probably_damaging	1	neutral	0,44	neutral	2,86	neutral	-1,5	deleterious	-2,59	medium_impact	3,09	neutral	0,94	neutral	0,38	deleterious	1,88	15,47	0,05	0,35	neutral	0,43	disease	0,78	disease	0,6	disease	0,54	1	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,8	low_impact	-3,53	medium_impact	0,17	medium_impact	1,61	0,37	0,8	42,11	12,09	N	0,49	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15796	15796	T	G	MI.10564	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1050	350	I	M	atT/atG	7,27	1	0	probably_damaging	1	neutral	0,26	neutral	2,85	neutral	-1,78	neutral	-1,56	medium_impact	2,72	neutral	0,92	neutral	0,62	deleterious	1,85	15,31	0,18	0,45	neutral	0,46	disease	0,68	disease	0,58	disease	0,58	2	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,73	low_impact	-3,53	medium_impact	-0,02	medium_impact	1,28	0,63	0,8	42,11	12,09	N	0,54	P	0,83	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15796	15796	T	A	MI.10565	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1050	350	I	M	atT/atA	7,27	1	0	probably_damaging	1	neutral	0,26	neutral	2,85	neutral	-1,78	neutral	-1,56	medium_impact	2,72	neutral	0,92	neutral	0,62	deleterious	2,1	16,85	0,18	0,45	neutral	0,46	disease	0,68	disease	0,58	disease	0,58	2	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,73	low_impact	-3,53	medium_impact	-0,02	medium_impact	1,28	0,63	0,8	42,11	12,09	N	0,54	P	0,83	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15797	15797	G	T	MI.10566	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1051	351	G	W	Gga/Tga	-7,4	0	0	probably_damaging	1	neutral	0,18	neutral	2,74	deleterious	-6,12	deleterious	-4,47	high_impact	4,95	neutral	0,86	damaging	0,05	deleterious	2,85	21,6	0,03	0,35	disease	0,96	disease	0,9	disease	0,78	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,14	high_impact	3,3	0,09	0,8	56,84	8,48	P	0,68	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15797	15797	G	C	MI.10567	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1051	351	G	R	Gga/Cga	-7,4	0	0	probably_damaging	1	neutral	0,33	neutral	2,79	deleterious	-3,07	deleterious	-4,47	high_impact	4,95	neutral	0,79	damaging	0,03	deleterious	2,37	18,65	0,03	0,35	disease	0,78	disease	0,9	disease	0,82	disease	0,8	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0,06	high_impact	3,3	0,38	0,8	56,84	8,48	P	0,71	P	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15798	15798	G	A	MI.10568	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1052	351	G	E	gGa/gAa	4,98	1	0	probably_damaging	0,99	neutral	0,28	neutral	2,83	neutral	-2,26	deleterious	-4,45	high_impact	4,4	neutral	0,72	damaging	0,04	deleterious	2,31	18,24	0,03	0,35	disease	0,69	disease	0,89	disease	0,82	disease	0,79	6	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,87	low_impact	-2,59	medium_impact	0	high_impact	2,8	0,23	0,8	56,84	8,48	P	0,61	P	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15798	15798	G	C	MI.10569	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1052	351	G	A	gGa/gCa	4,98	1	0	possibly_damaging	0,49	neutral	0,49	neutral	2,83	neutral	-2,3	deleterious	-3,35	medium_impact	2,25	neutral	0,86	damaging	0,07	neutral	1,55	13,55	0,04	0,35	disease	0,53	disease	0,73	disease	0,69	disease	0,67	3	neutral	0,5	deleterious	0,5	NA	0	deleterious	0,64	medium_impact	-0,72	medium_impact	0,21	medium_impact	0,85	0,34	0,8	56,84	8,48	N	0,41	N	0,73	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9022	9022	G	C	MI.1057	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	496	166	A	P	Gca/Cca	-7,74	0	0	probably_damaging	1	deleterious	0	neutral	3,26	deleterious	-7,36	deleterious	-4,53	high_impact	4,54	damaging	0,41	neutral	0,44	deleterious	3,95	23,6	0,13	0,65	disease	0,96	disease	0,92	disease	0,8	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,6	low_impact	-1,4	high_impact	2,79	0,72	0,9	49,56	8,89	P	0,64	P	0,97	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15798	15798	G	T	MI.10570	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1052	351	G	V	gGa/gTa	4,98	1	0	probably_damaging	1	neutral	0,52	neutral	2,75	deleterious	-4,76	deleterious	-5,03	high_impact	4,95	neutral	0,81	damaging	0,06	deleterious	2,23	17,73	0,03	0,35	neutral	0,42	disease	0,91	disease	0,76	disease	0,76	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,24	high_impact	3,3	0,22	0,8	56,84	8,48	P	0,68	P	0,98	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15800	15800	C	G	MI.10571	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1054	352	Q	E	Caa/Gaa	-10,83	0	0	probably_damaging	0,96	neutral	0,27	neutral	2,92	neutral	-2,34	neutral	-1,66	high_impact	4,15	neutral	0,74	damaging	0,09	neutral	1,58	13,72	0,27	0,45	neutral	0,44	disease	0,83	disease	0,76	disease	0,74	5	neutral	0,96	neutral	0,16	deleterious	2	deleterious	0,81	low_impact	-2,02	medium_impact	-0,01	high_impact	2,57	0,52	0,8	57,89	8,44	N	0,42	N	0,93	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15800	15800	C	A	MI.10572	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1054	352	Q	K	Caa/Aaa	-10,83	0	0	probably_damaging	0,98	neutral	0,29	neutral	2,92	neutral	-2,38	neutral	-2,2	high_impact	3,55	neutral	0,84	damaging	0,07	deleterious	2,42	18,93	0,15	0,4	neutral	0,25	disease	0,88	disease	0,75	disease	0,73	5	deleterious	0,98	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-2,31	medium_impact	0,01	high_impact	2,03	0,51	0,8	57,89	8,44	N	0,35	N	1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15801	15801	A	C	MI.10573	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1055	352	Q	P	cAa/cCa	5,44	1	0	probably_damaging	1	neutral	0,2	neutral	2,89	deleterious	-3,19	deleterious	-3,31	high_impact	4,36	neutral	0,88	damaging	0,07	neutral	1,65	14,11	0,03	0,35	disease	0,72	disease	0,89	disease	0,79	disease	0,78	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,1	high_impact	2,77	0,29	0,8	57,89	8,44	P	0,6	P	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15801	15801	A	T	MI.10574	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1055	352	Q	L	cAa/cTa	5,44	1	0	probably_damaging	0,98	neutral	0,65	neutral	3,03	neutral	-0,94	deleterious	-3,87	medium_impact	3,04	neutral	0,87	damaging	0,07	deleterious	2,08	16,74	0,05	0,35	disease	0,57	disease	0,92	disease	0,69	disease	0,73	5	neutral	0,98	neutral	0,34	deleterious	1	deleterious	0,84	low_impact	-2,31	medium_impact	0,37	medium_impact	1,57	0,19	0,8	57,89	8,44	N	0,41	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15801	15801	A	G	MI.10575	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1055	352	Q	R	cAa/cGa	5,44	1	0	probably_damaging	0,99	neutral	0,35	neutral	2,95	neutral	-1,9	neutral	-2,18	medium_impact	2,98	neutral	0,83	damaging	0,08	deleterious	1,84	15,2	0,15	0,4	neutral	0,36	disease	0,89	disease	0,67	disease	0,65	3	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,82	low_impact	-2,59	medium_impact	0,08	medium_impact	1,51	0,31	0,8	57,89	8,44	N	0,4	N	0,99	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15802	15802	A	T	MI.10576	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1056	352	Q	H	caA/caT	5,44	1	0	probably_damaging	1	neutral	0,54	neutral	2,88	deleterious	-3,51	deleterious	-2,76	high_impact	5,04	neutral	0,87	damaging	0,08	deleterious	2,08	16,7	0,13	0,4	disease	0,65	disease	0,85	disease	0,79	disease	0,76	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,26	high_impact	3,38	0,59	0,8	57,89	8,44	P	0,75	P	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15802	15802	A	C	MI.10577	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1056	352	Q	H	caA/caC	5,44	1	0	probably_damaging	1	neutral	0,54	neutral	2,88	deleterious	-3,51	deleterious	-2,76	high_impact	5,04	neutral	0,87	damaging	0,08	deleterious	1,9	15,61	0,13	0,4	disease	0,65	disease	0,85	disease	0,79	disease	0,76	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,26	high_impact	3,38	0,59	0,8	57,89	8,44	P	0,75	P	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15803	15803	G	T	MI.10578	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1057	353	V	L	Gta/Tta	4,52	0,98	0	benign	0,12	neutral	0,73	neutral	2,99	neutral	-0,08	neutral	-0,16	neutral_impact	-0,12	neutral	0,93	neutral	0,92	neutral	-0,57	0,15	0,23	0,45	NA	NA	neutral	0,23	neutral	0,31	neutral	0,17	7	neutral	0,16	deleterious	0,81	neutral	-6	neutral	0,15	medium_impact	0,08	medium_impact	0,46	low_impact	-1,3	0,63	0,8	26,84	28,45	N	0,48	N	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15803	15803	G	C	MI.10579	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1057	353	V	L	Gta/Cta	4,52	0,98	0	benign	0,12	neutral	0,73	neutral	2,99	neutral	-0,08	neutral	-0,16	neutral_impact	-0,12	neutral	0,93	neutral	0,92	neutral	-0,67	0,09	0,23	0,45	NA	NA	neutral	0,23	neutral	0,31	neutral	0,17	7	neutral	0,16	deleterious	0,81	neutral	-6	neutral	0,15	medium_impact	0,08	medium_impact	0,46	low_impact	-1,3	0,63	0,8	26,84	28,45	N	0,48	N	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9023	9023	C	T	MI.1058	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	497	166	A	V	gCa/gTa	7,3	1	0	probably_damaging	1	neutral	0,15	neutral	3,39	deleterious	-5,98	deleterious	-3,59	high_impact	4,2	damaging	0,44	neutral	0,42	deleterious	4,49	24,3	0,32	0,65	disease	0,78	disease	0,91	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,13	high_impact	2,5	0,75	0,9	49,56	8,89	P	0,74	P	0,75	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15803	15803	G	A	MI.10580	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1057	353	V	M	Gta/Ata	4,52	0,98	0	benign	0,14	neutral	0,24	neutral	2,84	neutral	-1,85	neutral	-0,59	low_impact	1,18	neutral	0,9	neutral	0,89	neutral	1,09	11,14	0,21	0,45	NA	NA	neutral	0,34	neutral	0,39	neutral	0,15	7	neutral	0,72	deleterious	0,55	neutral	-6	neutral	0,16	medium_impact	0	medium_impact	-0,05	medium_impact	-0,12	0,61	0,8	26,84	28,45	P	0,62	P	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15804	15804	T	A	MI.10581	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1058	353	V	E	gTa/gAa	-7,62	0	0,01	possibly_damaging	0,79	neutral	0,27	neutral	2,8	deleterious	-3,09	deleterious	-2,58	high_impact	3,73	neutral	0,89	neutral	0,52	deleterious	3,44	23	0,02	0,35	NA	NA	disease	0,82	disease	0,72	disease	0,78	6	neutral	0,84	neutral	0,24	deleterious	1	deleterious	0,75	low_impact	-1,27	medium_impact	-0,01	high_impact	2,19	0,12	0,8	26,84	28,45	N	0,42	N	0,86	polymorphism	1	0,12	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15804	15804	T	G	MI.10582	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1058	353	V	G	gTa/gGa	-7,62	0	0,01	possibly_damaging	0,79	neutral	0,35	neutral	2,81	neutral	-2,74	deleterious	-3,04	medium_impact	2,83	neutral	0,91	neutral	0,47	deleterious	2,36	18,53	0,02	0,35	NA	NA	disease	0,67	disease	0,64	disease	0,71	4	neutral	0,81	neutral	0,28	NA	0	deleterious	0,63	low_impact	-1,27	medium_impact	0,08	medium_impact	1,38	0,26	0,8	26,84	28,45	N	0,34	N	0,81	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15804	15804	T	C	MI.10583	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1058	353	V	A	gTa/gCa	-7,62	0	0,01	benign	0,4	neutral	0,53	neutral	2,88	neutral	-1,17	neutral	-1,42	low_impact	1,07	neutral	0,89	neutral	0,85	neutral	0,92	10,22	0,11	0,4	NA	NA	neutral	0,32	neutral	0,43	neutral	0,15	7	neutral	0,42	deleterious	0,57	neutral	-6	neutral	0,32	medium_impact	-0,57	medium_impact	0,25	medium_impact	-0,22	0,15	0,8	26,84	28,45	N	0,31	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15806	15806	G	A	MI.10584	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1060	354	A	T	Gca/Aca	-1,89	0	0	benign	0,08	neutral	0,5	neutral	2,88	neutral	-1,34	neutral	-1,75	medium_impact	3,3	neutral	0,91	neutral	0,58	deleterious	2,69	20,7	0,12	0,4	NA	NA	disease	0,85	neutral	0,45	disease	0,64	3	neutral	0,44	deleterious	0,71	neutral	-3	neutral	0,31	medium_impact	0,26	medium_impact	0,22	medium_impact	1,8	0,76	0,85	53,16	7,53	N	0,31	N	0,79	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15806	15806	G	C	MI.10585	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1060	354	A	P	Gca/Cca	-1,89	0	0	probably_damaging	0,92	neutral	0,12	neutral	2,82	deleterious	-3,33	neutral	-2,45	high_impact	3,92	neutral	0,84	damaging	0,27	deleterious	2,3	18,16	0,03	0,35	NA	NA	disease	0,91	disease	0,68	disease	0,74	5	neutral	0,97	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-1,72	medium_impact	-0,25	high_impact	2,37	0,58	0,8	53,16	7,53	N	0,36	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15806	15806	G	T	MI.10586	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1060	354	A	S	Gca/Tca	-1,89	0	0	possibly_damaging	0,69	neutral	0,34	neutral	2,89	neutral	-1,11	neutral	-1,22	low_impact	1,82	neutral	0,91	neutral	0,6	deleterious	2,1	16,84	0,17	0,45	NA	NA	disease	0,81	neutral	0,42	neutral	0,5	0	neutral	0,74	neutral	0,33	neutral	-3	deleterious	0,54	low_impact	-1,06	medium_impact	0,07	medium_impact	0,46	0,58	0,8	53,16	7,53	N	0,32	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15807	15807	C	G	MI.10587	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1061	354	A	G	gCa/gGa	4,98	1	0	possibly_damaging	0,45	neutral	0,29	neutral	2,84	neutral	-2,37	neutral	-1,97	medium_impact	2,88	neutral	0,82	neutral	0,52	deleterious	2,38	18,71	0,17	0,45	NA	NA	disease	0,85	disease	0,53	disease	0,68	4	neutral	0,67	neutral	0,42	NA	0	deleterious	0,53	medium_impact	-0,65	medium_impact	0,01	medium_impact	1,42	0,68	0,85	53,16	7,53	N	0,5	N	0,83	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15807	15807	C	A	MI.10588	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1061	354	A	E	gCa/gAa	4,98	1	0	probably_damaging	0,93	neutral	0,16	neutral	2,83	neutral	-2,61	neutral	-2,4	high_impact	4,28	neutral	0,82	neutral	0,41	deleterious	3,06	22,4	0,03	0,35	NA	NA	disease	0,93	disease	0,67	disease	0,76	5	neutral	0,96	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-1,78	medium_impact	-0,17	high_impact	2,69	0,38	0,8	53,16	7,53	P	0,57	P	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15807	15807	C	T	MI.10589	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1061	354	A	V	gCa/gTa	4,98	1	0	possibly_damaging	0,57	neutral	0,51	neutral	2,94	neutral	-0,56	neutral	-1,96	medium_impact	3,12	neutral	0,84	neutral	0,51	deleterious	2,9	21,9	0,08	0,35	NA	NA	disease	0,9	disease	0,55	disease	0,68	4	neutral	0,55	deleterious	0,47	NA	0	deleterious	0,74	medium_impact	-0,85	medium_impact	0,23	medium_impact	1,64	0,7	0,85	53,16	7,53	N	0,51	P	0,84	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	9023	9023	C	A	MI.1059	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	497	166	A	E	gCa/gAa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	3,27	deleterious	-7,62	deleterious	-4,48	high_impact	4,54	damaging	0,53	neutral	0,44	deleterious	4,48	24,2	0,09	0,65	disease	0,98	disease	0,94	disease	0,77	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,6	low_impact	-1,4	high_impact	2,79	0,72	0,9	49,56	8,89	P	0,55	P	0,99	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15809	15809	T	A	MI.10590	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1063	355	S	T	Tcc/Acc	-3,27	0	0	probably_damaging	0,99	neutral	0,44	neutral	3,16	neutral	-0,06	neutral	-1,29	low_impact	1,29	neutral	0,87	damaging	0,08	deleterious	2,3	18,17	0,24	0,45	NA	NA	disease	0,66	neutral	0,39	neutral	0,41	2	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,82	low_impact	-2,59	medium_impact	0,17	medium_impact	-0,02	0,66	0,8	58,16	8,54	N	0,22	N	0,7	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15809	15809	T	G	MI.10591	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1063	355	S	A	Tcc/Gcc	-3,27	0	0	probably_damaging	0,99	neutral	0,66	neutral	2,98	neutral	-1,74	neutral	-1,54	medium_impact	2,75	neutral	0,84	damaging	0,19	deleterious	2,21	17,61	0,24	0,45	NA	NA	disease	0,64	disease	0,58	disease	0,56	1	deleterious	0,99	neutral	0,34	deleterious	1	deleterious	0,8	low_impact	-2,59	medium_impact	0,38	medium_impact	1,3	0,45	0,8	58,16	8,54	N	0,18	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15809	15809	T	C	MI.10592	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1063	355	S	P	Tcc/Ccc	-3,27	0	0	probably_damaging	1	neutral	0,17	neutral	2,93	deleterious	-3,04	deleterious	-2,58	high_impact	4,45	neutral	0,89	damaging	0,06	deleterious	2,44	19,11	0,03	0,35	NA	NA	disease	0,87	disease	0,74	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,15	high_impact	2,85	0,24	0,8	58,16	8,54	N	0,5	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15810	15810	C	G	MI.10593	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1064	355	S	C	tCc/tGc	7,27	1	0	probably_damaging	1	neutral	0,15	neutral	2,91	deleterious	-4,28	deleterious	-2,58	high_impact	4,8	neutral	0,86	damaging	0,05	deleterious	2	16,21	0,06	0,35	NA	NA	disease	0,85	disease	0,65	disease	0,72	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,19	high_impact	3,17	0,35	0,8	58,16	8,54	P	0,66	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15810	15810	C	T	MI.10594	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1064	355	S	F	tCc/tTc	7,27	1	0	probably_damaging	1	neutral	0,98	neutral	2,95	neutral	-2,44	deleterious	-3,12	high_impact	4,8	neutral	0,9	damaging	0,07	deleterious	2,62	20,3	0,03	0,35	NA	NA	disease	0,92	disease	0,65	disease	0,72	4	deleterious	1	deleterious	0,49	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	1,14	high_impact	3,17	0,12	0,8	58,16	8,54	P	0,65	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15810	15810	C	A	MI.10595	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1064	355	S	Y	tCc/tAc	7,27	1	0	probably_damaging	1	neutral	0,98	neutral	2,95	neutral	-2,46	deleterious	-3,12	high_impact	4,8	neutral	0,9	damaging	0,06	deleterious	2,58	19,99	0,04	0,35	NA	NA	disease	0,9	disease	0,69	disease	0,74	5	deleterious	1	deleterious	0,49	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	1,14	high_impact	3,17	0,26	0,8	58,16	8,54	P	0,66	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15812	15812	G	T	MI.10596	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1066	356	V	L	Gta/Tta	-7,85	0	0,01	benign	0	neutral	1	neutral	2,97	neutral	-0,07	neutral	-0,52	neutral_impact	0,32	neutral	0,86	neutral	0,71	neutral	0,99	10,6	0,19	0,45	NA	NA	neutral	0,47	neutral	0,39	neutral	0,27	5	neutral	0	deleterious	1	neutral	-6	neutral	0,14	high_impact	2,07	high_impact	1,85	medium_impact	-0,9	0,67	0,85	21,32	33,53	N	0,23	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15812	15812	G	C	MI.10597	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1066	356	V	L	Gta/Cta	-7,85	0	0,01	benign	0	neutral	1	neutral	2,97	neutral	-0,07	neutral	-0,52	neutral_impact	0,32	neutral	0,86	neutral	0,71	deleterious	0,88	9,95	0,19	0,45	NA	NA	neutral	0,47	neutral	0,39	neutral	0,27	5	neutral	0	deleterious	1	neutral	-6	neutral	0,14	high_impact	2,07	high_impact	1,85	medium_impact	-0,9	0,67	0,85	21,32	33,53	N	0,22	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15812	15812	G	A	MI.10598	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1066	356	V	M	Gta/Ata	-7,85	0	0,01	benign	0,03	neutral	0,24	neutral	2,81	neutral	-2,12	neutral	-0,73	low_impact	1,57	damaging	0,51	neutral	0,86	neutral	1,07	11,06	0,21	0,45	NA	NA	neutral	0,46	neutral	0,44	neutral	0,23	6	neutral	0,75	deleterious	0,61	neutral	-6	neutral	0,14	medium_impact	0,68	medium_impact	-0,05	medium_impact	0,23	0,7	0,85	21,32	33,53	P	0,55	P	0,04	disease_causing_automatic	0	0,02	rs200336777	Pathogenic	Leber's_optic_atrophy	RCV000010313.4	MedGen:OMIM:SNOMED_CT	.	.	CPD	6,69	G15812A	LHON	+	-	Reported/Secondary	19
chrM	15813	15813	T	C	MI.10599	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1067	356	V	A	gTa/gCa	-0,52	0	0,02	benign	0,01	neutral	0,5	neutral	2,94	neutral	-0,73	neutral	-1,23	low_impact	1,1	neutral	0,87	neutral	0,8	deleterious	0,88	9,97	0,14	0,4	NA	NA	neutral	0,34	neutral	0,45	neutral	0,15	7	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,14	medium_impact	1,13	medium_impact	0,22	medium_impact	-0,2	0,17	0,8	21,32	33,53	N	0,32	N	0,43	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8575	8575	C	G	MI.106	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	49	17	L	V	Cta/Gta	-11,44	0	0	probably_damaging	0,99	neutral	0,18	neutral	4,55	neutral	-1,15	neutral	-0,28	neutral_impact	0,56	neutral	0,91	neutral	0,95	deleterious	1,83	15,18	0,5	0,65	disease	0,52	neutral	0,36	neutral	0,32	neutral	0,36	3	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,71	low_impact	-2,65	medium_impact	-0,08	medium_impact	-0,62	0,71	0,9	28,76	21,22	N	0,48	N	0,35	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9023	9023	C	G	MI.1060	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	497	166	A	G	gCa/gGa	7,3	1	0	probably_damaging	0,99	deleterious	0	neutral	3,29	deleterious	-3,88	deleterious	-3,59	medium_impact	3,39	damaging	0,56	neutral	0,55	deleterious	4	23,6	0,2	0,65	disease	0,84	disease	0,87	disease	0,62	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,86	low_impact	-2,65	low_impact	-1,4	medium_impact	1,81	0,8	0,9	49,56	8,89	N	0,49	N	0,86	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15813	15813	T	A	MI.10600	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1067	356	V	E	gTa/gAa	-0,52	0	0,02	benign	0,21	neutral	0,23	neutral	2,78	deleterious	-3,24	neutral	-2,32	high_impact	3,87	neutral	0,89	neutral	0,5	deleterious	3,1	22,5	0,02	0,35	NA	NA	disease	0,87	disease	0,74	disease	0,81	6	neutral	0,73	deleterious	0,51	neutral	-2	neutral	0,36	medium_impact	-0,19	medium_impact	-0,06	high_impact	2,32	0,17	0,8	21,32	33,53	N	0,45	N	0,73	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15813	15813	T	G	MI.10601	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1067	356	V	G	gTa/gGa	-0,52	0	0,02	benign	0,3	neutral	0,4	neutral	2,79	deleterious	-3,04	deleterious	-2,72	medium_impact	2,62	neutral	0,87	neutral	0,46	deleterious	2,29	18,13	0,04	0,35	NA	NA	disease	0,71	disease	0,63	disease	0,69	4	neutral	0,52	deleterious	0,55	neutral	-3	neutral	0,36	medium_impact	-0,39	medium_impact	0,13	medium_impact	1,19	0,26	0,8	21,32	33,53	N	0,27	N	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15815	15815	C	G	MI.10602	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1069	357	L	V	Cta/Gta	-6,48	0	0	probably_damaging	0,98	neutral	0,46	neutral	2,88	neutral	-0,79	neutral	-0,88	medium_impact	2,08	neutral	0,96	neutral	0,66	neutral	1,8	14,99	0,33	0,5	NA	NA	disease	0,64	neutral	0,41	neutral	0,48	0	neutral	0,98	neutral	0,24	deleterious	1	deleterious	0,8	low_impact	-2,31	medium_impact	0,18	medium_impact	0,7	0,69	0,85	18,68	21,01	N	0,31	N	0,39	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15815	15815	C	A	MI.10603	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1069	357	L	M	Cta/Ata	-6,48	0	0	probably_damaging	1	neutral	0,19	neutral	2,81	neutral	-1,59	neutral	-0,59	low_impact	1,93	neutral	0,95	neutral	0,91	neutral	1,02	10,8	0,3	0,45	NA	NA	neutral	0,47	neutral	0,36	neutral	0,27	5	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,76	low_impact	-3,53	medium_impact	-0,12	medium_impact	0,56	0,49	0,8	18,68	21,01	N	0,43	N	0,06	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15816	15816	T	A	MI.10604	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1070	357	L	Q	cTa/cAa	-11,06	0	0	probably_damaging	1	neutral	0,2	neutral	2,74	deleterious	-3,46	neutral	-2,17	high_impact	3,95	neutral	0,94	neutral	0,48	deleterious	2,7	20,8	0,03	0,35	NA	NA	disease	0,78	disease	0,58	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,1	high_impact	2,39	0,21	0,8	18,68	21,01	N	0,42	N	0,56	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15816	15816	T	C	MI.10605	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1070	357	L	P	cTa/cCa	-11,06	0	0	probably_damaging	1	neutral	0,13	neutral	2,73	deleterious	-3,92	deleterious	-2,6	high_impact	4,29	neutral	0,93	neutral	0,33	deleterious	2,4	18,82	0,02	0,35	NA	NA	disease	0,89	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,23	high_impact	2,7	0,16	0,8	18,68	21,01	N	0,46	N	0,95	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15816	15816	T	G	MI.10606	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1070	357	L	R	cTa/cGa	-11,06	0	0	probably_damaging	1	neutral	0,12	neutral	2,74	deleterious	-3,19	neutral	-2,25	high_impact	4,29	neutral	0,94	neutral	0,42	deleterious	2,59	20,2	0,02	0,35	NA	NA	disease	0,91	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,25	high_impact	2,7	0,2	0,8	18,68	21,01	N	0,49	N	0,69	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15818	15818	T	A	MI.10607	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1072	358	Y	N	Tac/Aac	-6,71	0	0	probably_damaging	1	neutral	0,16	neutral	2,47	deleterious	-5,26	deleterious	-4,75	high_impact	5,14	neutral	0,92	damaging	0,14	deleterious	2,45	19,11	0,08	0,35	NA	NA	disease	0,87	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,17	high_impact	3,47	0,14	0,8	57,63	8,54	P	0,65	P	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15818	15818	T	C	MI.10608	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1072	358	Y	H	Tac/Cac	-6,71	0	0	probably_damaging	1	neutral	0,23	neutral	2,49	deleterious	-4,33	deleterious	-2,63	high_impact	4,11	neutral	0,92	damaging	0,09	deleterious	1,96	15,98	0,17	0,45	NA	NA	disease	0,86	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,06	high_impact	2,54	0,18	0,8	57,63	8,54	N	0,47	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15818	15818	T	G	MI.10609	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1072	358	Y	D	Tac/Gac	-6,71	0	0	probably_damaging	1	neutral	0,07	neutral	2,46	deleterious	-5,67	deleterious	-5,28	high_impact	5,14	neutral	0,89	damaging	0,12	deleterious	2,36	18,59	0,04	0,35	NA	NA	disease	0,91	disease	0,8	disease	0,82	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,39	high_impact	3,47	0,14	0,8	57,63	8,54	P	0,65	P	1	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9025	9025	G	A	MI.1061	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	499	167	G	S	Ggc/Agc	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,23	deleterious	-5,94	deleterious	-5,34	high_impact	4,08	damaging	0,55	neutral	0,5	deleterious	4,26	23,9	0,25	0,65	disease	0,9	disease	0,88	disease	0,73	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,4	0,65	0,9	49,12	8,62	N	0,3	N	0,98	disease_causing	1	0,35	rs28681063	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15819	15819	A	G	MI.10610	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1073	358	Y	C	tAc/tGc	4,52	1	0	probably_damaging	1	neutral	0,06	neutral	2,46	deleterious	-6,06	deleterious	-4,76	high_impact	5,14	neutral	0,94	damaging	0,07	deleterious	1,86	15,33	0,06	0,35	NA	NA	disease	0,9	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,43	high_impact	3,47	0,16	0,8	57,63	8,54	P	0,66	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15819	15819	A	C	MI.10611	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1073	358	Y	S	tAc/tCc	4,52	1	0	probably_damaging	1	neutral	0,18	neutral	2,48	deleterious	-4,64	deleterious	-4,75	high_impact	5,14	neutral	0,92	damaging	0,11	deleterious	2,09	16,77	0,08	0,35	NA	NA	disease	0,89	disease	0,73	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,14	high_impact	3,47	0,14	0,8	57,63	8,54	P	0,71	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15819	15819	A	T	MI.10612	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1073	358	Y	F	tAc/tTc	4,52	1	0	probably_damaging	1	neutral	0,86	neutral	2,6	neutral	-2,46	neutral	-2,12	medium_impact	3,23	neutral	0,94	damaging	0,11	neutral	1,74	14,66	0,26	0,45	NA	NA	disease	0,88	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,43	deleterious	1	deleterious	0,9	low_impact	-3,53	medium_impact	0,65	medium_impact	1,74	0,42	0,8	57,63	8,54	N	0,39	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15821	15821	T	A	MI.10613	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1075	359	F	I	Ttc/Atc	-0,52	0,13	0	probably_damaging	1	neutral	0,32	neutral	1,92	deleterious	-4,75	deleterious	-3,15	high_impact	3,94	neutral	0,94	damaging	0,12	deleterious	3,05	22,4	0,07	0,35	NA	NA	disease	0,84	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,05	high_impact	2,38	0,4	0,8	57,89	8,41	N	0,46	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15821	15821	T	G	MI.10614	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1075	359	F	V	Ttc/Gtc	-0,52	0,13	0	probably_damaging	1	neutral	0,26	neutral	1,91	deleterious	-4,86	deleterious	-3,67	high_impact	4,62	neutral	0,95	damaging	0,11	deleterious	2,66	20,6	0,06	0,35	NA	NA	disease	0,89	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,02	high_impact	3	0,36	0,8	57,89	8,41	P	0,6	P	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15821	15821	T	C	MI.10615	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1075	359	F	L	Ttc/Ctc	-0,52	0,13	0	probably_damaging	0,99	neutral	0,65	neutral	1,97	deleterious	-3,89	deleterious	-3,15	high_impact	3,56	neutral	0,95	damaging	0,09	deleterious	2,67	20,6	0,1	0,4	NA	NA	disease	0,82	disease	0,69	disease	0,71	4	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,84	low_impact	-2,59	medium_impact	0,37	high_impact	2,04	0,61	0,8	57,89	8,41	N	0,22	N	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15822	15822	T	G	MI.10616	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1076	359	F	C	tTc/tGc	4,52	1	0	probably_damaging	1	deleterious	0,02	neutral	1,86	deleterious	-7,7	deleterious	-4,2	high_impact	4,83	neutral	0,95	damaging	0,09	deleterious	2,58	19,99	0,03	0,35	NA	NA	disease	0,86	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-3,53	medium_impact	-0,69	high_impact	3,19	0,23	0,8	57,89	8,41	P	0,64	P	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15822	15822	T	C	MI.10617	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1076	359	F	S	tTc/tCc	4,52	1	0	probably_damaging	1	neutral	0,18	neutral	1,88	deleterious	-6,25	deleterious	-4,2	high_impact	4,62	neutral	0,96	damaging	0,09	deleterious	2,72	20,9	0,03	0,35	NA	NA	disease	0,87	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,14	high_impact	3	0,32	0,8	57,89	8,41	P	0,58	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15822	15822	T	A	MI.10618	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1076	359	F	Y	tTc/tAc	4,52	1	0	probably_damaging	0,99	neutral	0,87	neutral	2,03	deleterious	-3,26	neutral	-1,57	high_impact	4,28	neutral	0,95	damaging	0,11	deleterious	2,73	21	0,1	0,4	NA	NA	disease	0,8	disease	0,72	disease	0,72	4	deleterious	0,99	neutral	0,44	deleterious	2	deleterious	0,86	low_impact	-2,59	medium_impact	0,67	high_impact	2,69	0,5	0,8	57,89	8,41	N	0,45	N	0,88	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15823	15823	C	A	MI.10619	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1077	359	F	L	ttC/ttA	7,27	1	0	probably_damaging	0,99	neutral	0,65	neutral	1,97	deleterious	-3,89	deleterious	-3,15	high_impact	3,56	neutral	0,95	damaging	0,09	deleterious	3,11	22,5	0,1	0,4	NA	NA	disease	0,82	disease	0,69	disease	0,71	4	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,84	low_impact	-2,59	medium_impact	0,37	high_impact	2,04	0,61	0,8	57,89	8,41	N	0,45	N	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9025	9025	G	C	MI.1062	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	499	167	G	R	Ggc/Cgc	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,19	deleterious	-7,27	deleterious	-7,17	high_impact	4,63	damaging	0,41	neutral	0,3	deleterious	4,05	23,7	0,12	0,65	disease	0,95	disease	0,92	disease	0,82	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,93	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,59	0,9	49,12	8,62	P	0,67	P	0,98	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15823	15823	C	G	MI.10620	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1077	359	F	L	ttC/ttG	7,27	1	0	probably_damaging	0,99	neutral	0,65	neutral	1,97	deleterious	-3,89	deleterious	-3,15	high_impact	3,56	neutral	0,95	damaging	0,09	deleterious	2,8	21,4	0,1	0,4	NA	NA	disease	0,82	disease	0,69	disease	0,71	4	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,84	low_impact	-2,59	medium_impact	0,37	high_impact	2,04	0,61	0,8	57,89	8,41	N	0,45	N	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15824	15824	A	C	MI.10621	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1078	360	T	P	Aca/Cca	-0,52	0	0	benign	0,2	neutral	0,13	neutral	3,11	neutral	-2,05	neutral	-1,52	medium_impact	3,1	neutral	0,94	neutral	0,39	deleterious	0,61	8,24	0,06	0,35	NA	NA	disease	0,84	disease	0,55	disease	0,78	6	neutral	0,85	neutral	0,47	neutral	-3	deleterious	0,44	medium_impact	-0,17	medium_impact	-0,23	medium_impact	1,62	0,41	0,8	16,58	21,58	N	0,35	N	0,73	polymorphism	1	0,03	rs28357376	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15824	15824	A	T	MI.10622	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1078	360	T	S	Aca/Tca	-0,52	0	0	benign	0,02	neutral	0,31	neutral	3,21	neutral	0,07	neutral	-0,34	neutral_impact	-0,07	neutral	0,98	neutral	0,98	neutral	-0,76	0,05	0,24	0,45	NA	NA	neutral	0,13	neutral	0,24	neutral	0,19	6	neutral	0,68	deleterious	0,65	neutral	-6	neutral	0,09	medium_impact	0,85	medium_impact	0,03	low_impact	-1,26	0,59	0,8	16,58	21,58	N	0,47	N	0	polymorphism	1	0,01	rs28357376	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15824	15824	A	G	MI.10623	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1078	360	T	A	Aca/Gca	-0,52	0	0	benign	0	neutral	0,32	neutral	3,22	neutral	1,3	neutral	-0,37	neutral_impact	0,1	neutral	0,96	neutral	0,85	neutral	-0,09	1,8	0,17	0,45	NA	NA	neutral	0,27	neutral	0,3	neutral	0,17	7	neutral	0,68	deleterious	0,66	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,05	low_impact	-1,1	0,44	0,8	16,58	21,58	N	0,34	N	0,16	polymorphism	1	0,01	rs28357376	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15825	15825	C	A	MI.10624	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1079	360	T	K	aCa/aAa	-3,73	0	0	benign	0,04	neutral	0,07	neutral	3,12	neutral	-0,92	neutral	-1,28	medium_impact	3,1	neutral	0,94	neutral	0,49	neutral	1,45	13,03	0,08	0,35	NA	NA	disease	0,75	disease	0,53	disease	0,67	3	neutral	0,93	deleterious	0,52	neutral	-3	neutral	0,36	medium_impact	0,56	medium_impact	-0,39	medium_impact	1,62	0,49	0,8	16,58	21,58	N	0,35	N	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15825	15825	C	T	MI.10625	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1079	360	T	M	aCa/aTa	-3,73	0	0	benign	0,38	neutral	0,09	neutral	3,13	neutral	-0,5	neutral	-0,69	neutral_impact	0,7	neutral	0,89	neutral	0,78	neutral	0,97	10,49	0,1	0,4	NA	NA	neutral	0,36	neutral	0,29	neutral	0,16	7	neutral	0,9	neutral	0,36	neutral	-6	neutral	0,43	medium_impact	-0,53	medium_impact	-0,32	medium_impact	-0,56	0,69	0,85	16,58	21,58	N	0,45	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15827	15827	A	C	MI.10626	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1081	361	T	P	Aca/Cca	-10,37	0	0	possibly_damaging	0,66	neutral	0,16	neutral	3,13	neutral	-1,19	neutral	-1,32	medium_impact	2,21	neutral	0,84	neutral	0,44	deleterious	1,94	15,82	0,06	0,35	NA	NA	disease	0,83	disease	0,53	disease	0,78	6	neutral	0,86	neutral	0,25	NA	0	deleterious	0,73	medium_impact	-1	medium_impact	-0,17	medium_impact	0,81	0,33	0,8	18,68	29,24	N	0,3	N	0,85	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15827	15827	A	G	MI.10627	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1081	361	T	A	Aca/Gca	-10,37	0	0	benign	0,15	neutral	0,35	neutral	3,18	neutral	0,22	neutral	-0,4	medium_impact	2,21	neutral	0,78	neutral	0,75	deleterious	1,96	15,94	0,18	0,45	NA	NA	neutral	0,36	neutral	0,38	neutral	0,16	7	neutral	0,59	deleterious	0,6	neutral	-3	neutral	0,27	medium_impact	-0,03	medium_impact	0,08	medium_impact	0,81	0,46	0,8	18,68	29,24	N	0,39	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15827	15827	A	T	MI.10628	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1081	361	T	S	Aca/Tca	-10,37	0	0	benign	0,25	neutral	0,48	neutral	3,16	neutral	-0,25	neutral	-0,7	low_impact	1,27	neutral	0,84	neutral	0,63	deleterious	1,83	15,16	0,28	0,45	NA	NA	neutral	0,44	neutral	0,37	neutral	0,21	6	neutral	0,42	deleterious	0,62	neutral	-6	neutral	0,36	medium_impact	-0,29	medium_impact	0,2	medium_impact	-0,04	0,53	0,8	18,68	29,24	N	0,32	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15828	15828	C	A	MI.10629	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1082	361	T	K	aCa/aAa	-0,75	0	0	benign	0,35	neutral	0,16	neutral	3,14	neutral	-0,78	neutral	-1,08	medium_impact	2,21	neutral	0,84	neutral	0,55	deleterious	2,97	22,1	0,08	0,35	NA	NA	disease	0,72	disease	0,51	disease	0,56	1	neutral	0,81	neutral	0,41	neutral	-3	deleterious	0,53	medium_impact	-0,48	medium_impact	-0,17	medium_impact	0,81	0,57	0,8	18,68	29,24	N	0,33	N	0,82	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9025	9025	G	T	MI.1063	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	499	167	G	C	Ggc/Tgc	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,18	deleterious	-9,86	deleterious	-8,11	high_impact	4,63	damaging	0,46	neutral	0,29	deleterious	4,23	23,9	0,13	0,65	disease	0,99	disease	0,92	disease	0,74	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,52	0,9	49,12	8,62	N	0,44	N	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15828	15828	C	T	MI.10630	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1082	361	T	M	aCa/aTa	-0,75	0	0	benign	0,06	neutral	0,24	neutral	3,14	neutral	-0,74	neutral	0,62	low_impact	1,31	neutral	0,89	neutral	0,75	deleterious	2,39	18,74	0,11	0,4	NA	NA	neutral	0,49	neutral	0,27	neutral	0,45	1	neutral	0,74	deleterious	0,59	neutral	-6	neutral	0,17	medium_impact	0,38	medium_impact	-0,05	medium_impact	0	0,66	0,8	18,68	29,24	N	0,42	N	0,45	polymorphism	1	0,01	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15830	15830	A	T	MI.10631	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1084	362	I	F	Atc/Ttc	-8,08	0	0	probably_damaging	0,99	neutral	1	neutral	3,38	neutral	1,62	neutral	0,6	low_impact	0,98	neutral	0,97	neutral	0,3	deleterious	0,54	7,72	0,17	0,45	NA	NA	neutral	0,21	neutral	0,3	neutral	0,19	6	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,67	low_impact	-2,59	high_impact	1,85	medium_impact	-0,3	0,55	0,8	39,47	13,25	N	0,26	N	0,97	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15830	15830	A	C	MI.10632	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1084	362	I	L	Atc/Ctc	-8,08	0	0	probably_damaging	0,95	neutral	0,96	neutral	3,22	neutral	1,18	neutral	-0,31	neutral_impact	0,62	neutral	0,97	neutral	0,73	neutral	1,02	10,76	0,2	0,45	NA	NA	disease	0,52	neutral	0,32	neutral	0,45	1	neutral	0,95	deleterious	0,51	neutral	-2	deleterious	0,59	low_impact	-1,92	medium_impact	0,97	medium_impact	-0,63	0,4	0,8	39,47	13,25	N	0,23	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15830	15830	A	G	MI.10633	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1084	362	I	V	Atc/Gtc	-8,08	0	0	possibly_damaging	0,87	neutral	0,31	neutral	3,14	neutral	-0,01	neutral	-0,47	medium_impact	2,99	neutral	0,97	damaging	0,18	neutral	1,57	13,68	0,39	0,5	NA	NA	neutral	0,47	disease	0,55	neutral	0,49	0	neutral	0,89	neutral	0,22	NA	0	deleterious	0,58	low_impact	-1,5	medium_impact	0,03	medium_impact	1,52	0,48	0,8	39,47	13,25	N	0,39	N	0,51	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15831	15831	T	A	MI.10634	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1085	362	I	N	aTc/aAc	0,17	0,03	0	probably_damaging	1	neutral	0,19	neutral	3,07	neutral	-2,36	neutral	-2,36	medium_impact	3,45	neutral	0,94	damaging	0,13	deleterious	3,09	22,5	0,12	0,4	NA	NA	disease	0,82	disease	0,6	disease	0,75	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,78	low_impact	-3,53	medium_impact	-0,12	medium_impact	1,94	0,31	0,8	39,47	13,25	N	0,37	N	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15831	15831	T	G	MI.10635	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1085	362	I	S	aTc/aGc	0,17	0,03	0	probably_damaging	1	neutral	0,19	neutral	3,09	neutral	-1,31	neutral	-1,86	medium_impact	3,45	neutral	0,94	damaging	0,12	deleterious	2,77	21,2	0,05	0,35	NA	NA	disease	0,82	disease	0,57	disease	0,75	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,79	low_impact	-3,53	medium_impact	-0,12	medium_impact	1,94	0,23	0,8	39,47	13,25	N	0,37	N	0,96	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15831	15831	T	C	MI.10636	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1085	362	I	T	aTc/aCc	0,17	0,03	0	probably_damaging	1	neutral	0,21	neutral	3,11	neutral	-1,02	neutral	-1,61	medium_impact	3,1	neutral	0,96	damaging	0,16	deleterious	1,93	15,75	0,07	0,35	NA	NA	disease	0,58	disease	0,54	disease	0,66	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,73	low_impact	-3,53	medium_impact	-0,09	medium_impact	1,62	0,38	0,8	39,47	13,25	N	0,38	N	0,98	polymorphism	1	0,07	.	.	.	.	.	MNGIE fibroblasts / endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	15832	15832	C	G	MI.10637	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1086	362	I	M	atC/atG	5,67	0,86	0	probably_damaging	1	neutral	0,22	neutral	3,08	neutral	-1,21	neutral	-0,58	medium_impact	3,25	neutral	0,96	damaging	0,19	deleterious	1,88	15,45	0,25	0,45	NA	NA	disease	0,59	neutral	0,48	disease	0,51	0	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,71	low_impact	-3,53	medium_impact	-0,08	medium_impact	1,76	0,57	0,8	39,47	13,25	N	0,44	N	0,78	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15832	15832	C	A	MI.10638	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1086	362	I	M	atC/atA	5,67	0,86	0	probably_damaging	1	neutral	0,22	neutral	3,08	neutral	-1,21	neutral	-0,58	medium_impact	3,25	neutral	0,96	damaging	0,19	deleterious	2,34	18,46	0,25	0,45	NA	NA	disease	0,59	neutral	0,48	disease	0,51	0	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,71	low_impact	-3,53	medium_impact	-0,08	medium_impact	1,76	0,57	0,8	39,47	13,25	N	0,44	N	0,78	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15833	15833	C	A	MI.10639	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1087	363	L	M	Cta/Ata	-3,27	0	0,05	probably_damaging	1	neutral	0,22	neutral	2,9	neutral	-2,46	neutral	-0,9	medium_impact	2,88	neutral	0,88	neutral	0,48	deleterious	2,16	17,26	0,2	0,45	NA	NA	disease	0,52	disease	0,53	neutral	0,5	0	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,73	low_impact	-3,53	medium_impact	-0,08	medium_impact	1,42	0,51	0,8	23,95	24,64	N	0,42	N	0,63	polymorphism	1	0,04	rs41504845	Likely benign	not_provided	RCV000224196.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	9026	9026	G	A	MI.1064	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	500	167	G	D	gGc/gAc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,24	deleterious	-5,55	deleterious	-6,28	high_impact	4,29	damaging	0,53	neutral	0,34	deleterious	3,98	23,6	0,12	0,65	disease	0,7	disease	0,93	disease	0,81	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,6	low_impact	-1,4	high_impact	2,58	0,29	0,9	49,12	8,62	P	0,56	P	1	disease_causing	1	0,32	.	.	.	.	.	.	COSM1155688	.	.	.	.	.	.	.	.
chrM	15833	15833	C	G	MI.10640	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1087	363	L	V	Cta/Gta	-3,27	0	0,05	probably_damaging	0,92	neutral	0,23	neutral	2,98	neutral	-0,79	neutral	-1,2	medium_impact	2,65	neutral	0,9	neutral	0,67	deleterious	1,82	15,11	0,23	0,45	NA	NA	disease	0,57	disease	0,56	neutral	0,46	1	neutral	0,94	neutral	0,16	deleterious	1	deleterious	0,73	low_impact	-1,72	medium_impact	-0,06	medium_impact	1,21	0,44	0,8	23,95	24,64	N	0,41	N	0,64	polymorphism	1	0,04	rs41504845	Likely benign	not_provided	RCV000224196.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	15834	15834	T	C	MI.10641	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1088	363	L	P	cTa/cCa	-0,29	0	0	probably_damaging	1	deleterious	0,04	neutral	2,89	deleterious	-4,11	deleterious	-3,25	high_impact	4,42	neutral	0,83	neutral	0,29	deleterious	2,37	18,66	0,03	0,35	NA	NA	disease	0,82	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,87	low_impact	-3,53	medium_impact	-0,53	high_impact	2,82	0,37	0,8	23,95	24,64	N	0,43	N	0,92	polymorphism	1	0,2	rs878937787	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15834	15834	T	A	MI.10642	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1088	363	L	Q	cTa/cAa	-0,29	0	0	probably_damaging	1	neutral	0,05	neutral	2,89	deleterious	-3,63	deleterious	-2,82	high_impact	4,42	neutral	0,84	neutral	0,38	deleterious	2,55	19,79	0,04	0,35	NA	NA	disease	0,76	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	-0,47	high_impact	2,82	0,33	0,8	23,95	24,64	N	0,46	N	0,93	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15834	15834	T	G	MI.10643	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1088	363	L	R	cTa/cGa	-0,29	0	0	probably_damaging	1	neutral	0,07	neutral	2,9	deleterious	-3,49	deleterious	-2,84	high_impact	4,42	neutral	0,84	neutral	0,33	deleterious	2,62	20,3	0,03	0,35	NA	NA	disease	0,88	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,39	high_impact	2,82	0,16	0,8	23,95	24,64	N	0,49	N	0,99	polymorphism	1	0,35	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15836	15836	A	G	MI.10644	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1090	364	I	V	Atc/Gtc	-5,56	0	0	benign	0	neutral	0,52	neutral	3,13	neutral	-0,13	neutral	-0,18	neutral_impact	0,54	neutral	1	neutral	0,97	neutral	-0,28	0,75	0,46	0,55	NA	NA	neutral	0,12	neutral	0,33	neutral	0,23	5	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,24	medium_impact	-0,7	0,43	0,8	18,42	19,71	N	0,35	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15836	15836	A	C	MI.10645	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1090	364	I	L	Atc/Ctc	-5,56	0	0	benign	0	neutral	1	neutral	3,15	neutral	-0,79	neutral	-0,56	neutral_impact	0,61	neutral	0,97	neutral	0,85	neutral	0,98	10,55	0,24	0,45	NA	NA	neutral	0,49	neutral	0,31	neutral	0,34	3	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,07	high_impact	1,85	medium_impact	-0,64	0,39	0,8	18,42	19,71	N	0,24	N	0,11	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15836	15836	A	T	MI.10646	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1090	364	I	F	Atc/Ttc	-5,56	0	0	benign	0,11	neutral	0,83	neutral	3,05	neutral	-2,71	neutral	-1,49	low_impact	1,45	neutral	0,96	neutral	0,84	deleterious	2,17	17,31	0,18	0,45	NA	NA	disease	0,67	neutral	0,37	neutral	0,49	0	neutral	0,07	deleterious	0,86	neutral	-6	neutral	0,16	medium_impact	0,12	medium_impact	0,6	medium_impact	0,12	0,4	0,8	18,42	19,71	N	0,2	N	0,77	polymorphism	1	0,04	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15837	15837	T	A	MI.10647	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1091	364	I	N	aTc/aAc	-4,64	0	0	possibly_damaging	0,62	neutral	0,17	neutral	2,98	deleterious	-4,38	deleterious	-2,87	high_impact	3,87	neutral	0,93	neutral	0,49	deleterious	3,09	22,5	0,12	0,4	NA	NA	disease	0,78	disease	0,64	disease	0,72	4	neutral	0,84	neutral	0,28	deleterious	1	neutral	0,38	medium_impact	-0,93	medium_impact	-0,15	high_impact	2,32	0,27	0,8	18,42	19,71	N	0,44	N	0,98	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15837	15837	T	C	MI.10648	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1091	364	I	T	aTc/aCc	-4,64	0	0	benign	0,09	neutral	0,28	neutral	3,04	neutral	-2,51	neutral	-1,8	medium_impact	3,06	neutral	0,98	neutral	0,69	deleterious	0,82	9,61	0,13	0,4	NA	NA	disease	0,54	neutral	0,45	neutral	0,47	1	neutral	0,68	deleterious	0,6	neutral	-3	neutral	0,17	medium_impact	0,21	medium_impact	0	medium_impact	1,59	0,27	0,8	18,42	19,71	N	0,38	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15837	15837	T	G	MI.10649	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1091	364	I	S	aTc/aGc	-4,64	0	0	benign	0,24	neutral	0,45	neutral	3,02	deleterious	-3,24	neutral	-2,36	medium_impact	2,83	neutral	0,93	neutral	0,67	deleterious	2,76	21,1	0,05	0,35	NA	NA	disease	0,8	neutral	0,46	disease	0,64	3	neutral	0,46	deleterious	0,61	neutral	-3	neutral	0,25	medium_impact	-0,26	medium_impact	0,18	medium_impact	1,38	0,24	0,8	18,42	19,71	N	0,3	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9026	9026	G	T	MI.1065	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	500	167	G	V	gGc/gTc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,18	deleterious	-8,86	deleterious	-8,07	high_impact	4,63	damaging	0,43	neutral	0,36	deleterious	3,84	23,4	0,12	0,65	disease	0,96	disease	0,92	disease	0,76	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,45	0,9	49,12	8,62	P	0,64	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15838	15838	C	G	MI.10650	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1092	364	I	M	atC/atG	4,52	0,62	0	benign	0,01	neutral	0,16	neutral	3,01	deleterious	-3,05	neutral	-0,86	medium_impact	2,51	neutral	0,95	neutral	0,54	deleterious	1,88	15,48	0,35	0,5	NA	NA	disease	0,52	neutral	0,36	neutral	0,48	1	neutral	0,84	deleterious	0,58	neutral	-3	neutral	0,12	medium_impact	1,13	medium_impact	-0,17	medium_impact	1,09	0,49	0,8	18,42	19,71	N	0,4	N	0,64	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15838	15838	C	A	MI.10651	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1092	364	I	M	atC/atA	4,52	0,62	0	benign	0,01	neutral	0,16	neutral	3,01	deleterious	-3,05	neutral	-0,86	medium_impact	2,51	neutral	0,95	neutral	0,54	deleterious	2,35	18,49	0,35	0,5	NA	NA	disease	0,52	neutral	0,36	neutral	0,48	1	neutral	0,84	deleterious	0,58	neutral	-3	neutral	0,12	medium_impact	1,13	medium_impact	-0,17	medium_impact	1,09	0,49	0,8	18,42	19,71	N	0,4	N	0,64	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15839	15839	C	A	MI.10652	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1093	365	L	M	Cta/Ata	-8,31	0	0	probably_damaging	0,99	neutral	0,28	neutral	2,97	neutral	-2,33	neutral	-0,72	low_impact	1,92	neutral	0,9	neutral	0,78	neutral	1,07	11,07	0,27	0,45	NA	NA	neutral	0,37	neutral	0,28	neutral	0,19	6	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,71	low_impact	-2,59	medium_impact	0	medium_impact	0,55	0,64	0,8	52,37	9,23	N	0,45	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15839	15839	C	G	MI.10653	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1093	365	L	V	Cta/Gta	-8,31	0	0	possibly_damaging	0,84	neutral	0,54	neutral	3,02	neutral	-0,45	neutral	-1,03	medium_impact	2,63	neutral	0,92	neutral	0,28	deleterious	1,81	15,03	0,24	0,45	NA	NA	disease	0,53	neutral	0,44	neutral	0,47	1	neutral	0,82	neutral	0,35	NA	0	deleterious	0,66	low_impact	-1,4	medium_impact	0,26	medium_impact	1,19	0,62	0,8	52,37	9,23	N	0,26	N	0,68	polymorphism	1	0,03	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15840	15840	T	A	MI.10654	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1094	365	L	Q	cTa/cAa	-3,27	0	0	probably_damaging	0,99	neutral	0,26	neutral	2,94	deleterious	-3,13	deleterious	-2,55	high_impact	4,08	neutral	0,86	damaging	0,14	deleterious	2,54	19,7	0,07	0,35	NA	NA	disease	0,73	neutral	0,49	neutral	0,49	0	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	-0,02	high_impact	2,51	0,26	0,8	52,37	9,23	N	0,35	N	0,93	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15840	15840	T	C	MI.10655	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1094	365	L	P	cTa/cCa	-3,27	0	0	probably_damaging	1	neutral	0,31	neutral	2,93	deleterious	-3,78	deleterious	-3,01	high_impact	4,08	neutral	0,87	damaging	0,09	deleterious	2,36	18,56	0,05	0,35	NA	NA	disease	0,83	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,03	high_impact	2,51	0,35	0,8	52,37	9,23	N	0,31	N	0,92	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15840	15840	T	G	MI.10656	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1094	365	L	R	cTa/cGa	-3,27	0	0	probably_damaging	0,99	neutral	0,33	neutral	2,95	deleterious	-3,05	deleterious	-2,59	high_impact	4,08	neutral	0,87	damaging	0,09	deleterious	2,6	20,2	0,04	0,35	NA	NA	disease	0,88	disease	0,63	disease	0,73	5	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-2,59	medium_impact	0,06	high_impact	2,51	0,25	0,8	52,37	9,23	N	0,3	N	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15842	15842	A	G	MI.10657	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1096	366	M	V	Ata/Gta	-11,75	0	0	benign	0	neutral	0,52	neutral	3,18	neutral	0,23	neutral	-0,59	medium_impact	2,7	neutral	0,98	neutral	0,63	neutral	1,01	10,7	0,19	0,45	NA	NA	disease	0,71	neutral	0,48	disease	0,52	0	neutral	0,48	deleterious	0,76	neutral	-3	neutral	0,21	high_impact	2,07	medium_impact	0,24	medium_impact	1,26	0,33	0,8	21,58	16,1	N	0,25	N	0,93	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15842	15842	A	T	MI.10658	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1096	366	M	L	Ata/Tta	-11,75	0	0	benign	0	neutral	0,93	neutral	3,27	neutral	1,35	neutral	-0,39	low_impact	1,38	neutral	0,97	neutral	0,77	deleterious	0,4	6,62	0,22	0,45	NA	NA	disease	0,63	neutral	0,31	neutral	0,45	1	neutral	0,05	deleterious	0,97	neutral	-6	neutral	0,19	high_impact	2,07	medium_impact	0,83	medium_impact	0,06	0,27	0,8	21,58	16,1	N	0,24	N	0,77	polymorphism	1	0,01	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15842	15842	A	C	MI.10659	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1096	366	M	L	Ata/Cta	-11,75	0	0	benign	0	neutral	0,93	neutral	3,27	neutral	1,35	neutral	-0,39	low_impact	1,38	neutral	0,97	neutral	0,77	deleterious	0,3	5,67	0,22	0,45	NA	NA	disease	0,63	neutral	0,31	neutral	0,45	1	neutral	0,05	deleterious	0,97	neutral	-6	neutral	0,19	high_impact	2,07	medium_impact	0,83	medium_impact	0,06	0,27	0,8	21,58	16,1	N	0,23	N	0,77	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9026	9026	G	C	MI.1066	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	500	167	G	A	gGc/gCc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,22	deleterious	-6	deleterious	-5,34	high_impact	4,63	damaging	0,56	neutral	0,45	deleterious	3,19	22,7	0,24	0,65	disease	0,91	disease	0,79	disease	0,7	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,6	0,9	49,12	8,62	P	0,54	P	0,79	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15843	15843	T	A	MI.10660	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1097	366	M	K	aTa/aAa	-0,29	0	0	benign	0,08	neutral	0,4	neutral	3,11	neutral	-2,15	neutral	-1,67	high_impact	3,64	neutral	0,93	neutral	0,34	deleterious	2,29	18,09	0,04	0,35	NA	NA	disease	0,87	disease	0,6	disease	0,75	5	neutral	0,55	deleterious	0,66	neutral	-2	neutral	0,4	medium_impact	0,26	medium_impact	0,13	high_impact	2,11	0,23	0,8	21,58	16,1	N	0,3	N	0,97	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15843	15843	T	C	MI.10661	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1097	366	M	T	aTa/aCa	-0,29	0	0	benign	0,07	neutral	0,39	neutral	3,14	neutral	-0,83	neutral	-1,11	medium_impact	2,57	neutral	0,92	neutral	0,48	neutral	1,17	11,59	0,15	0,4	NA	NA	disease	0,68	neutral	0,41	neutral	0,48	0	neutral	0,57	deleterious	0,66	neutral	-3	neutral	0,3	medium_impact	0,32	medium_impact	0,12	medium_impact	1,14	0,15	0,8	21,58	16,1	N	0,31	N	0,94	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15844	15844	A	T	MI.10662	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1098	366	M	I	atA/atT	2,69	0,06	0	benign	0,01	neutral	0,55	neutral	3,18	neutral	-0,27	neutral	-0,5	low_impact	1,31	neutral	0,95	neutral	0,7	deleterious	0,52	7,56	0,28	0,45	NA	NA	disease	0,53	neutral	0,35	neutral	0,45	1	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,18	medium_impact	1,13	medium_impact	0,27	medium_impact	0	0,36	0,8	21,58	16,1	N	0,28	N	0,85	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15844	15844	A	C	MI.10663	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1098	366	M	I	atA/atC	2,69	0,06	0	benign	0,01	neutral	0,55	neutral	3,18	neutral	-0,27	neutral	-0,5	low_impact	1,31	neutral	0,95	neutral	0,7	deleterious	0,44	6,99	0,28	0,45	NA	NA	disease	0,53	neutral	0,35	neutral	0,45	1	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,18	medium_impact	1,13	medium_impact	0,27	medium_impact	0	0,36	0,8	21,58	16,1	N	0,28	N	0,85	disease_causing	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15845	15845	C	G	MI.10664	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1099	367	P	A	Cca/Gca	-1,67	0	0	probably_damaging	0,97	neutral	0,66	neutral	3	deleterious	-4,23	deleterious	-3,92	high_impact	4,67	neutral	0,94	damaging	0,15	neutral	1,39	12,72	0,13	0,4	NA	NA	disease	0,63	disease	0,67	disease	0,67	3	neutral	0,97	neutral	0,35	deleterious	2	deleterious	0,78	low_impact	-2,14	medium_impact	0,38	high_impact	3,05	0,56	0,8	57,63	8,36	N	0,44	N	0,82	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15845	15845	C	T	MI.10665	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1099	367	P	S	Cca/Tca	-1,67	0	0	probably_damaging	0,99	neutral	0,55	neutral	2,98	deleterious	-4,46	deleterious	-3,92	high_impact	4,33	neutral	0,93	damaging	0,11	deleterious	3,6	23,2	0,13	0,4	NA	NA	disease	0,81	disease	0,58	disease	0,67	3	deleterious	0,99	neutral	0,28	deleterious	2	deleterious	0,84	low_impact	-2,59	medium_impact	0,27	high_impact	2,74	0,15	0,8	57,63	8,36	N	0,29	N	0,85	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15845	15845	C	A	MI.10666	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1099	367	P	T	Cca/Aca	-1,67	0	0	probably_damaging	0,99	neutral	0,5	neutral	2,99	deleterious	-4,87	deleterious	-3,91	high_impact	4,12	neutral	0,92	damaging	0,12	deleterious	3,38	23	0,15	0,4	NA	NA	disease	0,8	disease	0,65	disease	0,69	4	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	0,22	high_impact	2,55	0,45	0,8	57,63	8,36	N	0,32	N	0,96	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15846	15846	C	A	MI.10667	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1100	367	P	Q	cCa/cAa	5,44	0,99	0	probably_damaging	1	neutral	0,41	neutral	2,96	deleterious	-5,44	deleterious	-3,92	high_impact	4,67	neutral	0,93	damaging	0,09	deleterious	4,09	23,7	0,13	0,4	NA	NA	disease	0,85	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,14	high_impact	3,05	0,33	0,8	57,63	8,36	P	0,57	P	0,85	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15846	15846	C	G	MI.10668	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1100	367	P	R	cCa/cGa	5,44	0,99	0	probably_damaging	1	neutral	0,45	neutral	2,97	deleterious	-5,26	deleterious	-4,41	high_impact	4,33	neutral	0,96	damaging	0,09	deleterious	3,53	23,1	0,07	0,35	NA	NA	disease	0,9	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,18	high_impact	2,74	0,34	0,8	57,63	8,36	P	0,55	P	0,81	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15846	15846	C	T	MI.10669	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1100	367	P	L	cCa/cTa	5,44	0,99	0	probably_damaging	1	neutral	0,71	neutral	3,12	deleterious	-5,07	deleterious	-4,85	medium_impact	2,86	neutral	0,96	damaging	0,08	deleterious	4,28	24	0,08	0,35	NA	NA	disease	0,88	neutral	0,48	disease	0,73	5	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,85	low_impact	-3,53	medium_impact	0,43	medium_impact	1,4	0,56	0,8	57,63	8,36	N	0,38	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9028	9028	C	G	MI.1067	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	502	168	H	D	Cac/Gac	-20	0	0	probably_damaging	0,99	deleterious	0,01	neutral	4,09	deleterious	-3,67	deleterious	-7,88	high_impact	3,92	neutral	0,61	neutral	0,34	deleterious	3,9	23,5	0,2	0,65	disease	0,83	disease	0,9	disease	0,8	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,65	medium_impact	-0,84	high_impact	2,26	0,32	0,9	48,23	8,83	N	0,4	N	1	disease_causing	0,89	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15848	15848	A	C	MI.10670	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1102	368	T	P	Act/Cct	-12,9	0	0,01	benign	0,07	neutral	0,32	neutral	3,12	neutral	-2	neutral	-1,38	medium_impact	2,12	neutral	0,97	neutral	0,43	deleterious	1,83	15,17	0,07	0,35	NA	NA	disease	0,78	disease	0,63	disease	0,78	6	neutral	0,64	deleterious	0,63	neutral	-3	neutral	0,22	medium_impact	0,32	medium_impact	0,05	medium_impact	0,73	0,38	0,8	8,68	30,15	N	0,25	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15848	15848	A	G	MI.10671	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1102	368	T	A	Act/Gct	-12,9	0	0,01	benign	0	neutral	0,51	neutral	3,17	neutral	0,62	neutral	-0,46	neutral_impact	0,44	neutral	0,98	neutral	0,95	deleterious	0,5	7,47	0,38	0,5	NA	NA	neutral	0,21	neutral	0,42	neutral	0,17	7	neutral	0,49	deleterious	0,76	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,23	medium_impact	-0,79	0,44	0,8	8,68	30,15	N	0,33	N	0,04	polymorphism	1	0,01	rs1057520206	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15848	15848	A	T	MI.10672	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1102	368	T	S	Act/Tct	-12,9	0	0,01	benign	0	neutral	0,4	neutral	3,16	neutral	-0,42	neutral	-0,75	low_impact	1,43	neutral	0,96	neutral	0,84	neutral	1,53	13,45	0,42	0,55	NA	NA	neutral	0,32	neutral	0,39	neutral	0,15	7	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,13	medium_impact	0,11	0,51	0,8	8,68	30,15	N	0,34	N	0,22	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15849	15849	C	G	MI.10673	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1103	368	T	S	aCt/aGt	-9,23	0	0	benign	0	neutral	0,4	neutral	3,16	neutral	-0,42	neutral	-0,75	low_impact	1,43	neutral	0,96	neutral	0,84	neutral	1,6	13,86	0,42	0,55	NA	NA	neutral	0,32	neutral	0,39	neutral	0,15	7	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,13	medium_impact	0,11	0,51	0,8	8,68	30,15	N	0,31	N	0,22	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15849	15849	C	A	MI.10674	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1103	368	T	N	aCt/aAt	-9,23	0	0	benign	0,07	neutral	0,35	neutral	3,12	neutral	-1,63	neutral	-1,31	medium_impact	2,33	neutral	0,92	neutral	0,61	deleterious	2,01	16,25	0,36	0,5	NA	NA	disease	0,51	disease	0,53	disease	0,58	2	neutral	0,61	deleterious	0,64	neutral	-3	neutral	0,15	medium_impact	0,32	medium_impact	0,08	medium_impact	0,92	0,59	0,8	8,68	30,15	N	0,32	N	0,42	polymorphism	1	0,03	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15849	15849	C	T	MI.10675	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1103	368	T	I	aCt/aTt	-9,23	0	0	benign	0	neutral	0,47	neutral	3,28	neutral	1,24	neutral	0,39	neutral_impact	-0,79	neutral	0,98	neutral	0,98	deleterious	0,33	5,98	0,2	0,45	NA	NA	neutral	0,32	neutral	0,27	neutral	0,17	7	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,19	low_impact	-1,91	0,65	0,8	8,68	30,15	N	0,27	N	0,01	polymorphism	1	0	rs202225494	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	15851	15851	A	C	MI.10676	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1105	369	I	L	Atc/Ctc	-13,35	0	0,06	benign	0,02	neutral	0,74	neutral	3,22	neutral	-0,1	neutral	-0,13	low_impact	1,04	neutral	0,93	neutral	0,53	neutral	0,9	10,05	0,21	0,45	NA	NA	neutral	0,33	neutral	0,2	neutral	0,17	7	neutral	0,22	deleterious	0,86	neutral	-6	neutral	0,11	medium_impact	0,85	medium_impact	0,47	medium_impact	-0,25	0,42	0,8	13,42	21,02	N	0,35	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15851	15851	A	T	MI.10677	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1105	369	I	F	Atc/Ttc	-13,35	0	0,06	benign	0,14	neutral	0,74	neutral	3,11	neutral	-2,09	neutral	-0,82	medium_impact	2,29	neutral	0,98	neutral	0,82	deleterious	2,24	17,78	0,17	0,45	NA	NA	neutral	0,47	neutral	0,28	neutral	0,33	3	neutral	0,14	deleterious	0,8	neutral	-3	neutral	0,2	medium_impact	0	medium_impact	0,47	medium_impact	0,89	0,48	0,8	13,42	21,02	N	0,29	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15851	15851	A	G	MI.10678	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1105	369	I	V	Atc/Gtc	-13,35	0	0,06	benign	0,01	neutral	0,53	neutral	3,17	neutral	-0,31	neutral	0,19	low_impact	1,35	neutral	0,98	neutral	0,94	deleterious	0,01	2,65	0,25	0,45	NA	NA	neutral	0,17	neutral	0,25	neutral	0,22	6	neutral	0,46	deleterious	0,76	neutral	-6	neutral	0,09	medium_impact	1,13	medium_impact	0,25	medium_impact	0,03	0,23	0,8	13,42	21,02	N	0,34	N	0,04	polymorphism	1	0,01	rs3094281	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15852	15852	T	G	MI.10679	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1106	369	I	S	aTc/aGc	-4,87	0	0	benign	0	neutral	0,45	neutral	3,12	neutral	-1,99	neutral	-0,13	low_impact	0,88	neutral	0,96	neutral	0,97	neutral	1,31	12,35	0,06	0,35	NA	NA	neutral	0,47	neutral	0,29	neutral	0,27	5	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,13	high_impact	2,07	medium_impact	0,18	medium_impact	-0,39	0,14	0,8	13,42	21,02	N	0,36	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9028	9028	C	T	MI.1068	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	502	168	H	Y	Cac/Tac	-20	0	0	probably_damaging	0,98	deleterious	0	neutral	4,03	deleterious	-6,48	deleterious	-5,3	high_impact	4,62	damaging	0,56	damaging	0,27	deleterious	3,82	23,4	0,35	0,65	disease	0,95	disease	0,9	disease	0,75	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,36	low_impact	-1,4	high_impact	2,86	0,33	0,9	48,23	8,83	N	0,41	N	1	disease_causing	0,76	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15852	15852	T	C	MI.10680	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1106	369	I	T	aTc/aCc	-4,87	0	0	benign	0,05	neutral	0,43	neutral	3,15	neutral	-1,48	neutral	0,04	neutral_impact	-0,02	neutral	0,98	neutral	0,97	deleterious	0,07	3,28	0,13	0,4	NA	NA	neutral	0,14	neutral	0,26	neutral	0,19	6	neutral	0,53	deleterious	0,69	neutral	-6	neutral	0,09	medium_impact	0,46	medium_impact	0,16	low_impact	-1,21	0,23	0,8	13,42	21,02	N	0,39	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15852	15852	T	A	MI.10681	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1106	369	I	N	aTc/aAc	-4,87	0	0	benign	0,08	neutral	0,38	neutral	3,08	deleterious	-3,22	neutral	-1,09	medium_impact	2,22	neutral	0,92	neutral	0,53	deleterious	4,21	23,9	0,11	0,4	NA	NA	disease	0,61	neutral	0,33	neutral	0,5	0	neutral	0,57	deleterious	0,65	neutral	-3	neutral	0,19	medium_impact	0,26	medium_impact	0,11	medium_impact	0,82	0,14	0,8	13,42	21,02	N	0,3	N	0,02	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15853	15853	C	G	MI.10682	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1107	369	I	M	atC/atG	0,17	0	0	benign	0,31	neutral	0,23	neutral	3,09	neutral	-2,05	neutral	-0,21	low_impact	1,15	neutral	0,94	neutral	0,52	neutral	1,74	14,65	0,26	0,45	NA	NA	neutral	0,31	neutral	0,25	neutral	0,18	6	neutral	0,72	neutral	0,46	neutral	-6	neutral	0,18	medium_impact	-0,41	medium_impact	-0,06	medium_impact	-0,15	0,55	0,8	13,42	21,02	N	0,43	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15853	15853	C	A	MI.10683	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1107	369	I	M	atC/atA	0,17	0	0	benign	0,31	neutral	0,23	neutral	3,09	neutral	-2,05	neutral	-0,21	low_impact	1,15	neutral	0,94	neutral	0,52	deleterious	2,14	17,11	0,26	0,45	NA	NA	neutral	0,31	neutral	0,25	neutral	0,18	6	neutral	0,72	neutral	0,46	neutral	-6	neutral	0,18	medium_impact	-0,41	medium_impact	-0,06	medium_impact	-0,15	0,55	0,8	13,42	21,02	N	0,42	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15854	15854	T	A	MI.10684	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1108	370	S	T	Tcc/Acc	-4,64	0	0	probably_damaging	0,97	neutral	0,54	neutral	3,12	neutral	-0,04	neutral	-0,93	medium_impact	2,12	neutral	0,93	neutral	0,65	deleterious	2,04	16,46	0,21	0,45	NA	NA	neutral	0,44	neutral	0,35	neutral	0,21	6	neutral	0,97	neutral	0,29	deleterious	1	deleterious	0,69	low_impact	-2,14	medium_impact	0,26	medium_impact	0,73	0,52	0,8	18,68	18,73	N	0,28	N	0,48	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15854	15854	T	G	MI.10685	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1108	370	S	A	Tcc/Gcc	-4,64	0	0	probably_damaging	0,96	neutral	0,69	neutral	3,12	neutral	-0,89	neutral	-0,13	low_impact	1,88	neutral	0,97	neutral	0,83	deleterious	0,61	8,25	0,24	0,45	NA	NA	neutral	0,28	neutral	0,2	neutral	0,18	6	neutral	0,95	neutral	0,37	neutral	-2	deleterious	0,67	low_impact	-2,02	medium_impact	0,41	medium_impact	0,51	0,36	0,8	18,68	18,73	N	0,3	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15854	15854	T	C	MI.10686	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1108	370	S	P	Tcc/Ccc	-4,64	0	0	probably_damaging	0,99	neutral	0,28	neutral	3,06	neutral	-2,82	neutral	-1,36	medium_impact	3,22	neutral	0,94	neutral	0,34	deleterious	2,38	18,66	0,06	0,35	NA	NA	disease	0,89	disease	0,64	disease	0,79	6	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,82	low_impact	-2,59	medium_impact	0	medium_impact	1,73	0,18	0,8	18,68	18,73	N	0,34	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15855	15855	C	G	MI.10687	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1109	370	S	C	tCc/tGc	-0,52	0	0	probably_damaging	1	neutral	0,19	neutral	3,04	deleterious	-4,14	neutral	-1,51	high_impact	3,91	neutral	0,95	neutral	0,37	deleterious	3,48	23,1	0,09	0,35	NA	NA	disease	0,69	neutral	0,4	neutral	0,5	0	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,74	low_impact	-3,53	medium_impact	-0,12	high_impact	2,36	0,22	0,8	18,68	18,73	N	0,43	N	0,62	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15855	15855	C	A	MI.10688	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1109	370	S	Y	tCc/tAc	-0,52	0	0	probably_damaging	1	neutral	1	neutral	3,08	deleterious	-3,18	neutral	-1,8	medium_impact	3,22	neutral	0,94	neutral	0,51	deleterious	3,9	23,5	0,07	0,35	NA	NA	disease	0,76	neutral	0,3	disease	0,58	2	deleterious	0,99	deleterious	0,5	deleterious	1	deleterious	0,77	low_impact	-3,53	high_impact	1,85	medium_impact	1,73	0,28	0,8	18,68	18,73	N	0,19	N	0,9	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15855	15855	C	T	MI.10689	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1109	370	S	F	tCc/tTc	-0,52	0	0	probably_damaging	1	neutral	0,71	neutral	3,09	deleterious	-3,3	neutral	-1,82	medium_impact	3,02	neutral	0,95	neutral	0,49	deleterious	3,99	23,6	0,06	0,35	NA	NA	disease	0,77	neutral	0,46	disease	0,61	2	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,79	low_impact	-3,53	medium_impact	0,43	medium_impact	1,55	0,09	0,8	18,68	18,73	N	0,23	N	0,91	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9028	9028	C	A	MI.1069	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	502	168	H	N	Cac/Aac	-20	0	0	probably_damaging	0,98	deleterious	0	neutral	4,08	deleterious	-4,38	deleterious	-6,05	high_impact	4,62	damaging	0,57	neutral	0,33	deleterious	3,91	23,5	0,41	0,65	disease	0,86	disease	0,87	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,36	low_impact	-1,4	high_impact	2,86	0,42	0,9	48,23	8,83	N	0,44	N	0,98	disease_causing	0,72	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15857	15857	C	A	MI.10690	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1111	371	L	M	Cta/Ata	-5,33	0	0	probably_damaging	1	neutral	0,28	neutral	3,04	neutral	-1,45	neutral	-0,1	low_impact	1,15	neutral	0,93	neutral	0,87	deleterious	2,19	17,44	0,3	0,45	NA	NA	neutral	0,22	neutral	0,12	neutral	0,17	7	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,67	low_impact	-3,53	medium_impact	0	medium_impact	-0,15	0,68	0,85	12,63	28,66	N	0,53	P	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15857	15857	C	G	MI.10691	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1111	371	L	V	Cta/Gta	-5,33	0	0	probably_damaging	0,98	neutral	0,65	neutral	3,06	neutral	-1,02	neutral	-0,43	low_impact	1,87	neutral	0,97	neutral	0,72	deleterious	0,77	9,28	0,25	0,45	NA	NA	neutral	0,38	neutral	0,29	neutral	0,17	7	deleterious	0,98	neutral	0,34	neutral	-2	deleterious	0,69	low_impact	-2,31	medium_impact	0,37	medium_impact	0,51	0,48	0,8	12,63	28,66	N	0,29	N	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15858	15858	T	A	MI.10692	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1112	371	L	Q	cTa/cAa	-7,62	0	0	probably_damaging	1	neutral	0,57	neutral	3	neutral	-2,31	neutral	-1	medium_impact	2,84	neutral	0,93	neutral	0,63	deleterious	3,98	23,6	0,06	0,35	NA	NA	disease	0,61	neutral	0,36	neutral	0,48	0	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,73	low_impact	-3,53	medium_impact	0,29	medium_impact	1,39	0,18	0,8	12,63	28,66	N	0,26	N	0,6	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15858	15858	T	C	MI.10693	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1112	371	L	P	cTa/cCa	-7,62	0	0	probably_damaging	1	neutral	0,34	neutral	2,99	neutral	-2,69	neutral	-1,56	medium_impact	2,98	neutral	0,93	neutral	0,36	deleterious	3,84	23,4	0,04	0,35	NA	NA	disease	0,85	disease	0,52	disease	0,75	5	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,83	low_impact	-3,53	medium_impact	0,07	medium_impact	1,51	0,15	0,8	12,63	28,66	N	0,32	N	0,82	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15858	15858	T	G	MI.10694	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1112	371	L	R	cTa/cGa	-7,62	0	0	probably_damaging	1	neutral	0,59	neutral	3,03	neutral	-1,62	neutral	-1,16	medium_impact	1,99	neutral	0,94	neutral	0,48	deleterious	4,07	23,7	0,05	0,35	NA	NA	disease	0,84	neutral	0,44	disease	0,75	5	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,82	low_impact	-3,53	medium_impact	0,31	medium_impact	0,61	0,17	0,8	12,63	28,66	N	0,21	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15860	15860	A	G	MI.10695	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1114	372	I	V	Att/Gtt	-4,19	0	0,06	benign	0	neutral	0,48	neutral	3,14	neutral	-0,21	neutral	-0,21	low_impact	1,38	neutral	0,98	neutral	0,96	deleterious	-0,04	2,24	0,49	0,55	NA	NA	neutral	0,17	neutral	0,38	neutral	0,21	6	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,07	high_impact	2,07	medium_impact	0,2	medium_impact	0,06	0,36	0,8	19,47	32,29	N	0,34	N	0,09	polymorphism	1	0,01	rs201023973	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15860	15860	A	C	MI.10696	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1114	372	I	L	Att/Ctt	-4,19	0	0,06	benign	0,01	neutral	1	neutral	3,23	neutral	-0,08	neutral	0,15	low_impact	1,03	neutral	0,94	neutral	0,87	neutral	-0,13	1,54	0,23	0,45	NA	NA	neutral	0,14	neutral	0,13	neutral	0,2	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,07	medium_impact	1,13	high_impact	1,85	medium_impact	-0,26	0,65	0,8	19,47	32,29	N	0,34	N	0,25	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15860	15860	A	T	MI.10697	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1114	372	I	F	Att/Ttt	-4,19	0	0,06	benign	0,19	neutral	0,59	neutral	3,1	neutral	-1,65	neutral	-0,98	medium_impact	2,44	neutral	0,98	neutral	0,93	deleterious	1,93	15,77	0,12	0,4	NA	NA	neutral	0,47	neutral	0,24	neutral	0,27	5	neutral	0,3	deleterious	0,7	neutral	-3	neutral	0,39	medium_impact	-0,14	medium_impact	0,31	medium_impact	1,02	0,54	0,8	19,47	32,29	N	0,34	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15861	15861	T	A	MI.10698	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1115	372	I	N	aTt/aAt	-2,12	0	0	possibly_damaging	0,71	neutral	0,33	neutral	3,07	deleterious	-3,05	neutral	-2,25	medium_impact	3,28	neutral	0,86	neutral	0,51	deleterious	2,81	21,4	0,07	0,35	NA	NA	disease	0,65	neutral	0,47	neutral	0,48	0	neutral	0,76	neutral	0,31	NA	0	deleterious	0,63	low_impact	-1,09	medium_impact	0,06	medium_impact	1,79	0,19	0,8	19,47	32,29	N	0,34	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15861	15861	T	G	MI.10699	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1115	372	I	S	aTt/aGt	-2,12	0	0	benign	0,35	neutral	0,41	neutral	3,09	neutral	-2	neutral	-1,68	medium_impact	3,28	neutral	0,96	neutral	0,46	deleterious	2,59	20,1	0,02	0,35	NA	NA	disease	0,61	neutral	0,46	neutral	0,48	0	neutral	0,51	deleterious	0,53	neutral	-3	neutral	0,42	medium_impact	-0,48	medium_impact	0,14	medium_impact	1,79	0,16	0,8	19,47	32,29	N	0,3	N	0,81	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8575	8575	C	A	MI.107	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	49	17	L	M	Cta/Ata	-11,44	0	0	probably_damaging	1	neutral	0,36	neutral	4,48	neutral	-2,48	neutral	-0,98	low_impact	1,01	neutral	0,96	neutral	0,79	deleterious	2,39	18,77	0,38	0,65	disease	0,67	neutral	0,4	neutral	0,33	disease	0,64	3	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	0,15	medium_impact	-0,23	0,6	0,9	28,76	21,22	N	0,44	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9029	9029	A	T	MI.1070	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	503	168	H	L	cAc/cTc	4,52	0,99	0	probably_damaging	0,99	deleterious	0	neutral	4,05	deleterious	-5,27	deleterious	-9,7	high_impact	4,07	damaging	0,57	neutral	0,36	deleterious	4,41	24,1	0,22	0,65	disease	0,9	disease	0,93	disease	0,73	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,65	low_impact	-1,4	high_impact	2,39	0,38	0,9	48,23	8,83	P	0,5	N	0,96	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15861	15861	T	C	MI.10700	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1115	372	I	T	aTt/aCt	-2,12	0	0	benign	0,14	neutral	0,4	neutral	3,1	neutral	-1,64	neutral	-1,29	medium_impact	2,44	neutral	0,97	neutral	0,86	deleterious	0,57	7,94	0,05	0,35	NA	NA	neutral	0,35	neutral	0,45	neutral	0,16	7	neutral	0,53	deleterious	0,63	neutral	-3	neutral	0,26	medium_impact	0	medium_impact	0,13	medium_impact	1,02	0,16	0,8	19,47	32,29	N	0,37	N	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15862	15862	T	G	MI.10701	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1116	372	I	M	atT/atG	4,52	0,6	0,01	benign	0,34	neutral	0,29	neutral	3,09	neutral	-1,41	neutral	-0,17	low_impact	1,21	neutral	0,95	neutral	0,9	deleterious	0,18	4,52	0,22	0,45	NA	NA	neutral	0,21	neutral	0,17	neutral	0,2	6	neutral	0,65	deleterious	0,48	neutral	-6	neutral	0,28	medium_impact	-0,46	medium_impact	0,01	medium_impact	-0,1	0,58	0,8	19,47	32,29	N	0,46	N	0,66	polymorphism	1	0,01	rs386829263	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15862	15862	T	A	MI.10702	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1116	372	I	M	atT/atA	4,52	0,6	0,01	benign	0,34	neutral	0,29	neutral	3,09	neutral	-1,41	neutral	-0,17	low_impact	1,21	neutral	0,95	neutral	0,9	deleterious	0,51	7,5	0,22	0,45	NA	NA	neutral	0,21	neutral	0,17	neutral	0,2	6	neutral	0,65	deleterious	0,48	neutral	-6	neutral	0,28	medium_impact	-0,46	medium_impact	0,01	medium_impact	-0,1	0,58	0,8	19,47	32,29	N	0,46	N	0,66	polymorphism	1	0,01	rs386829263	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15863	15863	G	C	MI.10703	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1117	373	E	Q	Gaa/Caa	-5,33	0	0	probably_damaging	0,98	neutral	0,3	neutral	2,84	neutral	-2,63	neutral	-1,34	high_impact	3,56	neutral	0,91	damaging	0,11	neutral	1,74	14,61	0,18	0,45	NA	NA	disease	0,68	disease	0,57	disease	0,65	3	deleterious	0,98	neutral	0,16	deleterious	2	deleterious	0,82	low_impact	-2,31	medium_impact	0,02	high_impact	2,04	0,52	0,8	58,95	7,85	N	0,31	N	0,94	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15863	15863	G	A	MI.10704	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1117	373	E	K	Gaa/Aaa	-5,33	0	0	probably_damaging	0,98	neutral	0,31	neutral	2,88	neutral	-1,97	neutral	-1,8	high_impact	3,56	neutral	0,95	damaging	0,09	deleterious	2,91	21,9	0,07	0,35	NA	NA	disease	0,84	disease	0,64	disease	0,71	4	deleterious	0,98	neutral	0,17	deleterious	2	deleterious	0,87	low_impact	-2,31	medium_impact	0,03	high_impact	2,04	0,66	0,8	58,95	7,85	N	0,32	N	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15864	15864	A	C	MI.10705	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1118	373	E	A	gAa/gCa	7,04	1	0	probably_damaging	0,98	neutral	0,51	neutral	2,85	neutral	-2,56	deleterious	-2,7	high_impact	4,53	neutral	0,94	damaging	0,15	deleterious	2,19	17,45	0,05	0,35	NA	NA	disease	0,63	disease	0,67	disease	0,68	4	deleterious	0,98	neutral	0,27	deleterious	2	deleterious	0,81	low_impact	-2,31	medium_impact	0,23	high_impact	2,92	0,28	0,8	58,95	7,85	N	0,53	P	0,83	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15864	15864	A	T	MI.10706	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1118	373	E	V	gAa/gTa	7,04	1	0	probably_damaging	0,99	neutral	0,5	neutral	2,8	deleterious	-4,3	deleterious	-3,15	high_impact	4,53	neutral	0,93	damaging	0,13	deleterious	2,7	20,8	0,03	0,35	NA	NA	disease	0,82	disease	0,7	disease	0,74	5	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-2,59	medium_impact	0,22	high_impact	2,92	0,29	0,8	58,95	7,85	N	0,52	P	0,89	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15864	15864	A	G	MI.10707	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1118	373	E	G	gAa/gGa	7,04	1	0	probably_damaging	0,99	neutral	0,33	neutral	2,86	neutral	-2,31	deleterious	-3,14	medium_impact	3,11	neutral	0,96	damaging	0,19	deleterious	4	23,6	0,05	0,35	NA	NA	disease	0,69	disease	0,69	disease	0,68	4	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,83	low_impact	-2,59	medium_impact	0,06	medium_impact	1,63	0,26	0,8	58,95	7,85	N	0,52	P	0,77	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15865	15865	A	C	MI.10708	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1119	373	E	D	gaA/gaC	6,59	1	0	probably_damaging	0,91	neutral	0,22	neutral	3	neutral	-0,89	neutral	-1,34	medium_impact	2,41	neutral	0,91	damaging	0,1	deleterious	1,9	15,56	0,26	0,45	NA	NA	disease	0,64	neutral	0,36	neutral	0,48	0	neutral	0,94	neutral	0,16	deleterious	1	deleterious	0,78	low_impact	-1,67	medium_impact	-0,08	medium_impact	1	0,58	0,8	58,95	7,85	N	0,52	P	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15865	15865	A	T	MI.10709	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1119	373	E	D	gaA/gaT	6,59	1	0	probably_damaging	0,91	neutral	0,22	neutral	3	neutral	-0,89	neutral	-1,34	medium_impact	2,41	neutral	0,91	damaging	0,1	deleterious	2,03	16,4	0,26	0,45	NA	NA	disease	0,64	neutral	0,36	neutral	0,48	0	neutral	0,94	neutral	0,16	deleterious	1	deleterious	0,78	low_impact	-1,67	medium_impact	-0,08	medium_impact	1	0,58	0,8	58,95	7,85	N	0,52	P	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9029	9029	A	C	MI.1071	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	503	168	H	P	cAc/cCc	4,52	0,99	0	probably_damaging	0,99	deleterious	0	neutral	4,04	deleterious	-5,89	deleterious	-8,85	high_impact	4,62	damaging	0,47	neutral	0,33	deleterious	3,77	23,4	0,2	0,65	disease	0,93	disease	0,92	disease	0,81	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,91	low_impact	-2,65	low_impact	-1,4	high_impact	2,86	0,33	0,9	48,23	8,83	P	0,62	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15866	15866	A	C	MI.10710	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1120	374	N	H	Aac/Cac	0,63	0,99	0	probably_damaging	1	neutral	0,53	neutral	2,94	neutral	-2,91	neutral	-2,15	high_impact	3,9	neutral	0,93	neutral	0,32	deleterious	2,97	22,1	0,33	0,5	NA	NA	disease	0,66	neutral	0,5	neutral	0,49	0	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,25	high_impact	2,35	0,19	0,8	43,95	14,15	N	0,34	N	0,38	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15866	15866	A	G	MI.10711	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1120	374	N	D	Aac/Gac	0,63	0,99	0	probably_damaging	0,98	neutral	0,39	neutral	3,02	neutral	-1,29	neutral	-2,06	medium_impact	2,5	neutral	0,93	neutral	0,88	neutral	1,07	11,03	0,45	0,55	NA	NA	disease	0,51	neutral	0,32	neutral	0,42	2	deleterious	0,98	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-2,31	medium_impact	0,12	medium_impact	1,08	0,33	0,8	43,95	14,15	N	0,42	N	0,03	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15866	15866	A	T	MI.10712	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1120	374	N	Y	Aac/Tac	0,63	0,99	0	probably_damaging	1	neutral	1	neutral	2,94	neutral	-2,82	deleterious	-3,51	high_impact	3,64	neutral	0,97	neutral	0,43	deleterious	3,59	23,2	0,09	0,35	NA	NA	disease	0,77	neutral	0,5	disease	0,58	2	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,84	low_impact	-3,53	high_impact	1,85	high_impact	2,11	0,16	0,8	43,95	14,15	N	0,31	N	0,93	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15867	15867	A	C	MI.10713	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1121	374	N	T	aAc/aCc	4,29	1	0	probably_damaging	0,99	neutral	0,45	neutral	2,98	neutral	-1,81	deleterious	-2,62	medium_impact	2,56	neutral	0,94	neutral	0,46	deleterious	1,87	15,38	0,23	0,45	NA	NA	disease	0,68	disease	0,54	disease	0,6	2	deleterious	0,99	neutral	0,23	deleterious	1	deleterious	0,81	low_impact	-2,59	medium_impact	0,18	medium_impact	1,13	0,31	0,8	43,95	14,15	N	0,44	N	0,55	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15867	15867	A	G	MI.10714	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1121	374	N	S	aAc/aGc	4,29	1	0	probably_damaging	0,95	neutral	0,56	neutral	3,03	neutral	-1,18	neutral	-2,18	high_impact	3,56	neutral	0,95	neutral	0,5	neutral	1,29	12,21	0,41	0,5	NA	NA	disease	0,64	neutral	0,36	neutral	0,47	1	neutral	0,95	neutral	0,31	deleterious	2	deleterious	0,8	low_impact	-1,92	medium_impact	0,28	high_impact	2,04	0,24	0,8	43,95	14,15	N	0,4	N	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15867	15867	A	T	MI.10715	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1121	374	N	I	aAc/aTc	4,29	1	0	probably_damaging	1	neutral	0,44	neutral	2,92	deleterious	-4,15	deleterious	-3,97	high_impact	4,45	neutral	0,94	neutral	0,41	deleterious	3,84	23,4	0,11	0,4	NA	NA	disease	0,83	disease	0,53	disease	0,71	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,17	high_impact	2,85	0,13	0,8	43,95	14,15	N	0,53	P	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15868	15868	C	A	MI.10716	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1122	374	N	K	aaC/aaA	8,42	1	0	probably_damaging	1	neutral	0,52	neutral	3,1	neutral	-0,46	deleterious	-2,62	medium_impact	2	neutral	0,94	neutral	0,31	deleterious	4,5	24,3	0,28	0,45	NA	NA	disease	0,73	neutral	0,31	disease	0,5	0	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,84	low_impact	-3,53	medium_impact	0,24	medium_impact	0,62	0,41	0,8	43,95	14,15	N	0,46	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15868	15868	C	G	MI.10717	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1122	374	N	K	aaC/aaG	8,42	1	0	probably_damaging	1	neutral	0,52	neutral	3,1	neutral	-0,46	deleterious	-2,62	medium_impact	2	neutral	0,94	neutral	0,31	deleterious	4,04	23,7	0,28	0,45	NA	NA	disease	0,73	neutral	0,31	disease	0,5	0	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,84	low_impact	-3,53	medium_impact	0,24	medium_impact	0,62	0,41	0,8	43,95	14,15	N	0,46	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15869	15869	A	C	MI.10718	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1123	375	K	Q	Aaa/Caa	-1,44	0	0	benign	0,03	neutral	0,31	neutral	3,08	neutral	-1,36	neutral	-1,47	medium_impact	2,94	neutral	0,96	neutral	0,74	neutral	1,61	13,93	0,35	0,5	NA	NA	disease	0,58	neutral	0,45	neutral	0,46	1	neutral	0,67	deleterious	0,64	neutral	-3	neutral	0,19	medium_impact	0,68	medium_impact	0,03	medium_impact	1,48	0,34	0,8	19,21	24,09	N	0,35	N	0,56	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15869	15869	A	G	MI.10719	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1123	375	K	E	Aaa/Gaa	-1,44	0	0	benign	0,02	neutral	0,32	neutral	3,08	neutral	-0,9	neutral	-1,49	medium_impact	3,43	neutral	0,92	damaging	0,22	deleterious	2,18	17,41	0,21	0,45	NA	NA	disease	0,69	disease	0,53	disease	0,54	1	neutral	0,67	deleterious	0,65	neutral	-3	neutral	0,22	medium_impact	0,85	medium_impact	0,05	medium_impact	1,92	0,49	0,8	19,21	24,09	N	0,29	N	0,48	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9029	9029	A	G	MI.1072	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	503	168	H	R	cAc/cGc	4,52	0,99	0	probably_damaging	0,99	deleterious	0	neutral	4,07	deleterious	-4,68	deleterious	-7,02	high_impact	4,62	damaging	0,44	neutral	0,29	deleterious	3,56	23,1	0,37	0,65	disease	0,86	disease	0,9	disease	0,78	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,65	low_impact	-1,4	high_impact	2,86	0,3	0,9	48,23	8,83	P	0,72	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15870	15870	A	T	MI.10720	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1124	375	K	M	aAa/aTa	0,17	0	0	benign	0,35	neutral	0,24	neutral	3,09	neutral	-2,81	neutral	-2,21	medium_impact	2,94	neutral	0,96	neutral	0,4	deleterious	3,89	23,5	0,11	0,4	NA	NA	disease	0,59	neutral	0,27	neutral	0,47	1	neutral	0,71	neutral	0,45	neutral	-3	neutral	0,39	medium_impact	-0,48	medium_impact	-0,05	medium_impact	1,48	0,22	0,8	19,21	24,09	N	0,39	N	0,65	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15870	15870	A	C	MI.10721	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1124	375	K	T	aAa/aCa	0,17	0	0	benign	0,13	neutral	0,41	neutral	3,15	neutral	-1,07	neutral	-2,08	medium_impact	2,7	neutral	0,96	neutral	0,33	deleterious	2,24	17,8	0,17	0,45	NA	NA	disease	0,61	neutral	0,46	neutral	0,46	1	neutral	0,52	deleterious	0,64	neutral	-3	neutral	0,27	medium_impact	0,04	medium_impact	0,14	medium_impact	1,26	0,18	0,8	19,21	24,09	N	0,3	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15871	15871	A	T	MI.10722	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1125	375	K	N	aaA/aaT	2,92	0,02	0	benign	0,07	neutral	0,47	neutral	3,08	neutral	-1,64	neutral	-1,67	low_impact	1,13	neutral	0,96	neutral	0,88	neutral	1,19	11,72	0,46	0,55	NA	NA	neutral	0,45	neutral	0,31	neutral	0,21	6	neutral	0,47	deleterious	0,7	neutral	-6	neutral	0,23	medium_impact	0,32	medium_impact	0,19	medium_impact	-0,17	0,37	0,8	19,21	24,09	N	0,33	N	0,01	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15871	15871	A	C	MI.10723	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1125	375	K	N	aaA/aaC	2,92	0,02	0	benign	0,07	neutral	0,47	neutral	3,08	neutral	-1,64	neutral	-1,67	low_impact	1,13	neutral	0,96	neutral	0,88	neutral	1,14	11,42	0,46	0,55	NA	NA	neutral	0,45	neutral	0,31	neutral	0,21	6	neutral	0,47	deleterious	0,7	neutral	-6	neutral	0,23	medium_impact	0,32	medium_impact	0,19	medium_impact	-0,17	0,37	0,8	19,21	24,09	N	0,33	N	0,01	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15872	15872	A	C	MI.10724	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1126	376	M	L	Ata/Cta	-2,12	0	0	possibly_damaging	0,63	neutral	0,78	neutral	3,35	neutral	1,6	neutral	-0,11	neutral_impact	-0,9	neutral	0,98	neutral	0,98	neutral	-1,16	0,01	0,38	0,5	NA	NA	neutral	0,08	neutral	0,24	neutral	0,18	6	neutral	0,56	deleterious	0,58	neutral	-3	neutral	0,38	medium_impact	-0,95	medium_impact	0,52	low_impact	-2,01	0,29	0,8	16,58	27,37	N	0,39	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15872	15872	A	T	MI.10725	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1126	376	M	L	Ata/Tta	-2,12	0	0	possibly_damaging	0,63	neutral	0,78	neutral	3,35	neutral	1,6	neutral	-0,11	neutral_impact	-0,9	neutral	0,98	neutral	0,98	neutral	-1,09	0,01	0,38	0,5	NA	NA	neutral	0,08	neutral	0,24	neutral	0,18	6	neutral	0,56	deleterious	0,58	neutral	-3	neutral	0,38	medium_impact	-0,95	medium_impact	0,52	low_impact	-2,01	0,29	0,8	16,58	27,37	N	0,39	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15872	15872	A	G	MI.10726	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1126	376	M	V	Ata/Gta	-2,12	0	0	possibly_damaging	0,73	neutral	0,49	neutral	3,19	neutral	0,32	neutral	-0,48	low_impact	1,66	neutral	0,97	neutral	0,67	deleterious	-0,03	2,31	0,37	0,5	NA	NA	neutral	0,24	neutral	0,5	neutral	0,17	7	neutral	0,71	neutral	0,38	neutral	-3	deleterious	0,53	low_impact	-1,13	medium_impact	0,21	medium_impact	0,31	0,2	0,8	16,58	27,37	N	0,37	N	0,58	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15873	15873	T	C	MI.10727	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1127	376	M	T	aTa/aCa	-3,73	0	0	probably_damaging	0,94	neutral	0,39	neutral	3,15	neutral	-0,35	neutral	-0,95	medium_impact	2,55	neutral	0,95	neutral	0,53	deleterious	0,38	6,44	0,16	0,45	NA	NA	neutral	0,29	neutral	0,42	neutral	0,17	7	neutral	0,94	neutral	0,23	deleterious	1	deleterious	0,68	low_impact	-1,85	medium_impact	0,12	medium_impact	1,12	0,11	0,8	16,58	27,37	N	0,37	N	0,75	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15873	15873	T	A	MI.10728	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1127	376	M	K	aTa/aAa	-3,73	0	0	possibly_damaging	0,87	neutral	0,39	neutral	3,16	neutral	-0,13	neutral	-1,51	medium_impact	2,29	neutral	0,95	neutral	0,43	deleterious	2,56	19,88	0,1	0,4	NA	NA	disease	0,52	neutral	0,43	disease	0,53	1	neutral	0,87	neutral	0,26	NA	0	deleterious	0,71	low_impact	-1,5	medium_impact	0,12	medium_impact	0,89	0,24	0,8	16,58	27,37	N	0,3	N	0,93	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15874	15874	A	C	MI.10729	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1128	376	M	I	atA/atC	2	0,02	0,09	possibly_damaging	0,8	neutral	0,42	neutral	3,21	neutral	0,52	neutral	-0,43	neutral_impact	0,32	neutral	0,97	neutral	0,82	deleterious	0,42	6,8	0,32	0,5	NA	NA	neutral	0,17	neutral	0,25	neutral	0,22	6	neutral	0,8	neutral	0,31	neutral	-3	deleterious	0,56	low_impact	-1,29	medium_impact	0,15	medium_impact	-0,9	0,24	0,8	16,58	27,37	N	0,42	N	0,41	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9030	9030	C	A	MI.1073	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	504	168	H	Q	caC/caA	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	4,08	deleterious	-4,35	deleterious	-7,02	high_impact	4,07	damaging	0,56	neutral	0,33	deleterious	4	23,6	0,44	0,65	disease	0,85	disease	0,88	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,65	low_impact	-1,4	high_impact	2,39	0,42	0,9	48,23	8,83	N	0,48	N	0,95	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15874	15874	A	T	MI.10730	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1128	376	M	I	atA/atT	2	0,02	0,09	possibly_damaging	0,8	neutral	0,42	neutral	3,21	neutral	0,52	neutral	-0,43	neutral_impact	0,32	neutral	0,97	neutral	0,82	deleterious	0,47	7,2	0,32	0,5	NA	NA	neutral	0,17	neutral	0,25	neutral	0,22	6	neutral	0,8	neutral	0,31	neutral	-3	deleterious	0,56	low_impact	-1,29	medium_impact	0,15	medium_impact	-0,9	0,24	0,8	16,58	27,37	N	0,42	N	0,41	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15875	15875	C	G	MI.10731	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1129	377	L	V	Ctc/Gtc	-10,6	0	0	probably_damaging	0,95	neutral	0,48	neutral	3,05	neutral	-0,81	neutral	-1,12	medium_impact	3,12	neutral	0,96	damaging	0,13	deleterious	1,92	15,7	0,31	0,45	NA	NA	neutral	0,32	neutral	0,37	neutral	0,18	6	neutral	0,95	neutral	0,27	deleterious	1	deleterious	0,71	low_impact	-1,92	medium_impact	0,2	medium_impact	1,64	0,29	0,8	29,74	16,44	N	0,33	N	0,88	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15875	15875	C	A	MI.10732	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1129	377	L	I	Ctc/Atc	-10,6	0	0	probably_damaging	0,98	neutral	0,49	neutral	3,04	neutral	-0,86	neutral	-0,76	medium_impact	2,21	neutral	0,97	neutral	0,31	deleterious	2,69	20,7	0,32	0,5	NA	NA	neutral	0,29	neutral	0,17	neutral	0,2	6	deleterious	0,98	neutral	0,26	deleterious	1	deleterious	0,71	low_impact	-2,31	medium_impact	0,21	medium_impact	0,81	0,42	0,8	29,74	16,44	N	0,39	N	0,83	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15875	15875	C	T	MI.10733	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1129	377	L	F	Ctc/Ttc	-10,6	0	0	probably_damaging	0,99	neutral	0,74	neutral	3,02	neutral	-2,33	neutral	-1,48	medium_impact	2,54	neutral	0,96	damaging	0,14	deleterious	3,94	23,5	0,31	0,45	NA	NA	neutral	0,36	neutral	0,23	neutral	0,2	6	deleterious	0,99	neutral	0,38	deleterious	1	deleterious	0,75	low_impact	-2,59	medium_impact	0,47	medium_impact	1,11	0,39	0,8	29,74	16,44	N	0,24	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15876	15876	T	G	MI.10734	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1130	377	L	R	cTc/cGc	-0,98	0	0	probably_damaging	1	neutral	0,32	neutral	2,99	deleterious	-3,17	neutral	-2,29	high_impact	3,87	neutral	0,95	damaging	0,07	deleterious	4,32	24	0,04	0,35	NA	NA	disease	0,68	neutral	0,5	neutral	0,48	0	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,05	high_impact	2,32	0,14	0,8	29,74	16,44	N	0,34	N	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15876	15876	T	C	MI.10735	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1130	377	L	P	cTc/cCc	-0,98	0	0	probably_damaging	1	neutral	0,19	neutral	3,01	deleterious	-4,25	deleterious	-2,71	medium_impact	3,31	neutral	0,95	damaging	0,08	deleterious	4,2	23,9	0,04	0,35	NA	NA	disease	0,63	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,85	low_impact	-3,53	medium_impact	-0,12	medium_impact	1,81	0,11	0,8	29,74	16,44	N	0,35	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15876	15876	T	A	MI.10736	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1130	377	L	H	cTc/cAc	-0,98	0	0	probably_damaging	1	neutral	0,5	neutral	2,97	deleterious	-4,18	deleterious	-2,64	high_impact	4,21	neutral	0,94	damaging	0,09	deleterious	4,48	24,2	0,07	0,35	NA	NA	disease	0,53	neutral	0,31	neutral	0,47	1	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,22	high_impact	2,63	0,24	0,8	29,74	16,44	N	0,32	N	0,95	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15878	15878	A	C	MI.10737	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1132	378	K	Q	Aaa/Caa	-1,21	0	0	probably_damaging	0,94	neutral	0,45	neutral	3,09	neutral	-1,09	neutral	-0,93	medium_impact	2,6	neutral	0,96	neutral	0,44	neutral	1,79	14,92	0,53	0,6	NA	NA	neutral	0,32	neutral	0,25	neutral	0,2	6	neutral	0,93	neutral	0,26	deleterious	1	deleterious	0,68	low_impact	-1,85	medium_impact	0,18	medium_impact	1,17	0,54	0,8	37,11	17,49	N	0,4	N	0,69	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15878	15878	A	G	MI.10738	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1132	378	K	E	Aaa/Gaa	-1,21	0	0	probably_damaging	0,94	neutral	0,55	neutral	3,12	neutral	-0,43	neutral	-0,86	medium_impact	2,5	neutral	0,96	neutral	0,45	deleterious	2,35	18,48	0,31	0,45	NA	NA	neutral	0,41	neutral	0,4	neutral	0,17	7	neutral	0,93	neutral	0,31	deleterious	1	deleterious	0,73	low_impact	-1,85	medium_impact	0,27	medium_impact	1,08	0,7	0,85	37,11	17,49	N	0,29	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15879	15879	A	T	MI.10739	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1133	378	K	M	aAa/aTa	0,4	0,09	0	probably_damaging	0,99	neutral	0,25	neutral	3,06	neutral	-2,62	neutral	-1,71	medium_impact	3,5	neutral	0,95	neutral	0,45	deleterious	3,81	23,4	0,22	0,45	NA	NA	neutral	0,4	neutral	0,26	neutral	0,22	6	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,7	low_impact	-2,59	medium_impact	-0,04	medium_impact	1,98	0,18	0,8	37,11	17,49	N	0,5	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9030	9030	C	G	MI.1074	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	504	168	H	Q	caC/caG	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	4,08	deleterious	-4,35	deleterious	-7,02	high_impact	4,07	damaging	0,56	neutral	0,33	deleterious	3,67	23,3	0,44	0,65	disease	0,85	disease	0,88	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,65	low_impact	-1,4	high_impact	2,39	0,42	0,9	48,23	8,83	N	0,47	N	0,95	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15879	15879	A	C	MI.10740	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1133	378	K	T	aAa/aCa	0,4	0,09	0	probably_damaging	0,98	neutral	0,54	neutral	3,11	neutral	-1,09	neutral	-1,51	high_impact	3,85	neutral	0,95	neutral	0,46	deleterious	2,22	17,62	0,34	0,5	NA	NA	neutral	0,41	neutral	0,39	neutral	0,19	6	neutral	0,98	neutral	0,28	deleterious	2	deleterious	0,73	low_impact	-2,31	medium_impact	0,26	high_impact	2,3	0,14	0,8	37,11	17,49	N	0,34	N	0,79	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15880	15880	A	T	MI.10741	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1134	378	K	N	aaA/aaT	5,44	0,87	0	probably_damaging	0,99	neutral	0,44	neutral	3,14	neutral	-1,07	neutral	-0,76	low_impact	1,77	neutral	0,94	neutral	0,6	neutral	1,29	12,22	0,7	0,75	NA	NA	neutral	0,17	neutral	0,22	neutral	0,25	5	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,7	low_impact	-2,59	medium_impact	0,17	medium_impact	0,41	0,32	0,8	37,11	17,49	N	0,47	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15880	15880	A	C	MI.10742	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1134	378	K	N	aaA/aaC	5,44	0,87	0	probably_damaging	0,99	neutral	0,44	neutral	3,14	neutral	-1,07	neutral	-0,76	low_impact	1,77	neutral	0,94	neutral	0,6	neutral	1,25	12,03	0,7	0,75	NA	NA	neutral	0,17	neutral	0,22	neutral	0,25	5	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,7	low_impact	-2,59	medium_impact	0,17	medium_impact	0,41	0,32	0,8	37,11	17,49	N	0,48	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15881	15881	T	C	MI.10743	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1135	379	W	R	Tgg/Cgg	-0,06	0,77	0	probably_damaging	1	neutral	0,35	neutral	3,16	neutral	-0,16	deleterious	-2,9	medium_impact	3,16	neutral	0,68	damaging	0,07	deleterious	3,59	23,2	0,17	0,45	NA	NA	disease	0,58	disease	0,51	disease	0,53	1	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-3,53	medium_impact	0,08	medium_impact	1,68	0,14	0,8	NA	NA	N	0,28	N	0,96	polymorphism	1	0,06	.	.	.	.	.	.	COSM5656137	.	.	.	.	.	.	.	.
chrM	15881	15881	T	G	MI.10744	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1135	379	W	G	Tgg/Ggg	-0,06	0,77	0	probably_damaging	0,99	neutral	0,33	neutral	3,14	neutral	-0,65	deleterious	-2,86	medium_impact	3,36	neutral	0,81	damaging	0,15	deleterious	2,51	19,53	0,14	0,4	NA	NA	neutral	0,49	disease	0,59	neutral	0,5	0	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,76	low_impact	-2,59	medium_impact	0,06	medium_impact	1,86	0,14	0,8	NA	NA	N	0,28	N	0,9	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15882	15882	G	C	MI.10745	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1136	379	W	S	tGg/tCg	4,52	0,87	0	probably_damaging	1	neutral	0,41	neutral	3,17	neutral	0,08	deleterious	-2,86	medium_impact	2,67	neutral	0,8	damaging	0,12	deleterious	3,8	23,4	0,15	0,45	NA	NA	disease	0,6	neutral	0,5	disease	0,52	0	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,79	low_impact	-3,53	medium_impact	0,14	medium_impact	1,23	0,13	0,8	NA	NA	N	0,29	N	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15882	15882	G	T	MI.10746	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1136	379	W	L	tGg/tTg	4,52	0,87	0	probably_damaging	0,99	neutral	0,66	neutral	3,29	neutral	1,45	neutral	-2,24	low_impact	1,18	neutral	0,81	damaging	0,1	deleterious	2,78	21,3	0,18	0,45	NA	NA	neutral	0,41	disease	0,51	neutral	0,23	5	deleterious	0,99	neutral	0,34	neutral	-2	deleterious	0,75	low_impact	-2,59	medium_impact	0,38	medium_impact	-0,12	0,17	0,8	NA	NA	N	0,3	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15883	15883	G	C	MI.10747	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1137	379	W	C	tgG/tgC	-0,52	0,05	0,02	probably_damaging	1	neutral	0,18	neutral	3,12	neutral	-1,8	deleterious	-2,62	medium_impact	3,36	neutral	0,83	damaging	0,06	deleterious	4,06	23,7	0,13	0,4	NA	NA	disease	0,53	disease	0,59	disease	0,65	3	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,76	low_impact	-3,53	medium_impact	-0,14	medium_impact	1,86	0,09	0,8	NA	NA	N	0,29	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15883	15883	G	T	MI.10748	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1137	379	W	C	tgG/tgT	-0,52	0,05	0,02	probably_damaging	1	neutral	0,18	neutral	3,12	neutral	-1,8	deleterious	-2,62	medium_impact	3,36	neutral	0,83	damaging	0,06	deleterious	4,22	23,9	0,13	0,4	NA	NA	disease	0,53	disease	0,59	disease	0,65	3	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,76	low_impact	-3,53	medium_impact	-0,14	medium_impact	1,86	0,09	0,8	NA	NA	N	0,29	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15884	15884	G	T	MI.10749	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1138	380	A	S	Gcc/Tcc	3,61	0,12	0,1	possibly_damaging	0,52	neutral	0,42	neutral	4,63	neutral	-0,51	neutral	-0,04	neutral_impact	0,34	neutral	0,99	neutral	0,86	deleterious	0,44	6,91	0,28	0,45	NA	NA	neutral	0,03	neutral	0,17	neutral	0,11	8	neutral	0,57	neutral	0,45	neutral	-3	neutral	0,05	medium_impact	-0,76	medium_impact	0,15	medium_impact	-0,89	0,48	0,8	NA	NA	P	0,6	P	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9031	9031	C	G	MI.1075	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	505	169	L	V	Cta/Gta	-4,5	0	0	probably_damaging	0,99	neutral	0,08	neutral	4,11	neutral	-1,26	deleterious	-2,63	medium_impact	2,68	damaging	0,31	neutral	0,47	deleterious	3,47	23	0,34	0,65	disease	0,54	disease	0,61	disease	0,55	disease	0,62	2	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,76	low_impact	-2,65	medium_impact	-0,31	medium_impact	1,2	0,65	0,9	50,88	8,57	P	0,63	P	0,87	polymorphism	0,63	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15884	15884	G	A	MI.10750	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1138	380	A	T	Gcc/Acc	3,61	0,12	0,1	possibly_damaging	0,52	neutral	0,4	neutral	4,6	neutral	-0,83	neutral	-0,01	neutral_impact	-0,34	neutral	1	neutral	0,78	deleterious	3,98	23,6	0,2	0,45	NA	NA	neutral	0,18	neutral	0,44	neutral	0,26	5	neutral	0,59	neutral	0,44	neutral	-3	neutral	0,04	medium_impact	-0,76	medium_impact	0,13	low_impact	-1,5	0,5	0,8	NA	NA	P	0,58	P	0,05	polymorphism	1	0,01	rs527236195	Likely pathogenic,Benign	Neoplasm_of_ovary,not_specified	RCV000133439.1,RCV000238892.1	Gene:MedGen:OMIM:SNOMED_CT,MedGen	.	.	.	.	.	.	.	.	.	.
chrM	15884	15884	G	C	MI.10751	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1138	380	A	P	Gcc/Ccc	3,61	0,12	0,1	possibly_damaging	0,75	neutral	0,21	neutral	4,55	neutral	-1,65	neutral	-0,3	neutral_impact	0,7	neutral	1	neutral	0,34	deleterious	3,78	23,4	0,18	0,45	NA	NA	neutral	0,43	neutral	0,44	neutral	0,27	5	neutral	0,85	neutral	0,23	neutral	-3	neutral	0,13	low_impact	-1,18	medium_impact	-0,09	medium_impact	-0,56	0,37	0,8	NA	NA	N	0,56	P	0,09	polymorphism	1	0,01	rs527236195	Likely pathogenic,Benign	Neoplasm_of_ovary,not_specified	RCV000133439.1,RCV000238892.1	Gene:MedGen:OMIM:SNOMED_CT,MedGen	pancreatic cancer cell line	.	.	.	.	.	.	.	.	.
chrM	15885	15885	C	T	MI.10752	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1139	380	A	V	gCc/gTc	0,4	0,01	0	possibly_damaging	0,52	neutral	0,5	neutral	4,64	neutral	-0,32	neutral	-0,27	neutral_impact	0,14	neutral	0,99	neutral	0,78	deleterious	4,3	24	0,21	0,45	NA	NA	neutral	0,2	neutral	0,46	neutral	0,27	5	neutral	0,52	deleterious	0,49	neutral	-3	neutral	0,06	medium_impact	-0,76	medium_impact	0,22	low_impact	-1,07	0,5	0,8	NA	NA	N	0,45	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15885	15885	C	G	MI.10753	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1139	380	A	G	gCc/gGc	0,4	0,01	0	possibly_damaging	0,52	neutral	0,34	neutral	4,59	neutral	-0,65	neutral	-0,27	neutral_impact	0,7	neutral	1	neutral	0,8	deleterious	2,44	19,08	0,23	0,45	NA	NA	neutral	0,16	neutral	0,42	neutral	0,24	5	neutral	0,64	neutral	0,41	neutral	-3	neutral	0,04	medium_impact	-0,76	medium_impact	0,07	medium_impact	-0,56	0,39	0,8	NA	NA	N	0,51	P	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15885	15885	C	A	MI.10754	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1139	380	A	D	gCc/gAc	0,4	0,01	0	possibly_damaging	0,75	neutral	0,21	neutral	4,57	neutral	-1,02	neutral	-0,28	neutral_impact	0,7	neutral	1	neutral	0,44	deleterious	4,44	24,2	0,2	0,45	NA	NA	neutral	0,43	disease	0,51	neutral	0,3	4	neutral	0,85	neutral	0,23	neutral	-3	neutral	0,09	low_impact	-1,18	medium_impact	-0,09	medium_impact	-0,56	0,28	0,8	NA	NA	N	0,51	P	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3307	3307	A	C	MI.10755	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	1	1	M	L	Ata/Cta	-4,38	0	0	probably_damaging	0,93	deleterious	0	neutral	2,95	neutral	1,34	neutral	-0,72	NA	NA	neutral	0,69	damaging	0,19	neutral	1,01	10,73	0,06	0,35	NA	NA	neutral	0,12	neutral	0,16	neutral	0,16	7	deleterious	1	neutral	0,04	deleterious	4	deleterious	0,67	NA	NA	NA	NA	NA	NA	0,38	0,8	56,92	9,83	P	0,52	P	0,44	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3307	3307	A	T	MI.10756	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	1	1	M	L	Ata/Tta	-4,38	0	0	probably_damaging	0,93	deleterious	0	neutral	2,95	neutral	1,34	neutral	-0,72	NA	NA	neutral	0,69	damaging	0,19	neutral	1,09	11,15	0,06	0,35	NA	NA	neutral	0,12	neutral	0,16	neutral	0,16	7	deleterious	1	neutral	0,04	deleterious	4	deleterious	0,67	NA	NA	NA	NA	NA	NA	0,38	0,8	56,92	9,83	P	0,52	P	0,44	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3307	3307	A	G	MI.10757	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	1	1	M	V	Ata/Gta	-4,38	0	0	probably_damaging	0,97	deleterious	0	neutral	2,89	neutral	0,91	neutral	-0,88	NA	NA	neutral	0,61	damaging	0,2	deleterious	0,74	9,08	0,08	0,35	NA	NA	neutral	0,17	neutral	0,41	neutral	0,18	6	deleterious	1	neutral	0,02	deleterious	4	deleterious	0,7	NA	NA	NA	NA	NA	NA	0,26	0,8	56,92	9,83	N	0,36	N	0,07	NA	NA	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3308	3308	T	C	MI.10758	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	2	1	M	T	aTa/aCa	3,67	0,98	0,01	probably_damaging	0,99	deleterious	0	neutral	2,8	neutral	-0,17	neutral	-0,26	NA	NA	damaging	0,53	damaging	0,2	deleterious	2,36	18,57	0,07	0,35	NA	NA	neutral	0,28	disease	0,51	neutral	0,24	5	deleterious	1	neutral	0,01	deleterious	4	deleterious	0,74	NA	NA	NA	NA	NA	NA	0,08	0,8	56,92	9,83	P	0,75	P	0,05	NA	NA	0,01	rs28358582	Pathogenic|Pathogenic|Likely benign,Pathogenic	Carcinoma_of_colon|SUDDEN_INFANT_DEATH_SYNDROME|not_specified,SUDDEN_INFANT_DEATH_SYNDROME	RCV000010379.2|RCV000010380.4|RCV000239184.1,RCV000010381.2	MedGen:OMIM:SNOMED_CT|EFO:MedGen:OMIM:SNOMED_CT|MedGen,EFO:MedGen:OMIM:SNOMED_CT	colorectal tumor	.	.	.	T3308C	MELAS/DEAF enhancer/hypertension/LVNC/putative LHON	-	+	P.M.-possibly synergistic	14
chrM	3308	3308	T	A	MI.10759	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	2	1	M	K	aTa/aAa	3,67	0,98	0,01	probably_damaging	0,99	deleterious	0	neutral	2,81	neutral	-0,08	neutral	-1,86	NA	NA	damaging	0,52	damaging	0,15	deleterious	3,39	23	0,06	0,35	NA	NA	neutral	0,43	disease	0,54	neutral	0,32	4	deleterious	1	neutral	0,01	deleterious	4	deleterious	0,76	NA	NA	NA	NA	NA	NA	0,17	0,8	56,92	9,83	P	0,71	P	0,79	NA	NA	0,02	rs28358582	Pathogenic|Pathogenic|Likely benign,Pathogenic	Carcinoma_of_colon|SUDDEN_INFANT_DEATH_SYNDROME|not_specified,SUDDEN_INFANT_DEATH_SYNDROME	RCV000010379.2|RCV000010380.4|RCV000239184.1,RCV000010381.2	MedGen:OMIM:SNOMED_CT|EFO:MedGen:OMIM:SNOMED_CT|MedGen,EFO:MedGen:OMIM:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	9031	9031	C	A	MI.1076	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	505	169	L	M	Cta/Ata	-4,5	0	0	probably_damaging	1	neutral	0,09	neutral	3,91	deleterious	-3,77	neutral	-1,68	medium_impact	2,92	damaging	0,57	neutral	0,62	deleterious	3,98	23,6	0,29	0,65	disease	0,59	disease	0,61	disease	0,54	disease	0,53	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,28	medium_impact	1,41	0,59	0,9	50,88	8,57	N	0,35	N	0,96	polymorphism	0,68	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3309	3309	A	T	MI.10760	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	3	1	M	I	atA/atT	4,58	1	0	probably_damaging	0,98	deleterious	0	neutral	2,88	neutral	0,75	neutral	-1,01	NA	NA	damaging	0,57	damaging	0,16	neutral	1,67	14,21	0,07	0,35	NA	NA	neutral	0,2	neutral	0,17	neutral	0,2	6	deleterious	1	neutral	0,01	deleterious	4	deleterious	0,73	NA	NA	NA	NA	NA	NA	0,46	0,8	56,92	9,83	P	0,63	P	0,37	NA	NA	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3309	3309	A	C	MI.10761	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	3	1	M	I	atA/atC	4,58	1	0	probably_damaging	0,98	deleterious	0	neutral	2,88	neutral	0,75	neutral	-1,01	NA	NA	damaging	0,57	damaging	0,16	neutral	1,58	13,73	0,07	0,35	NA	NA	neutral	0,2	neutral	0,17	neutral	0,2	6	deleterious	1	neutral	0,01	deleterious	4	deleterious	0,73	NA	NA	NA	NA	NA	NA	0,46	0,8	56,92	9,83	P	0,63	P	0,37	NA	NA	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3310	3310	C	T	MI.10762	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	4	2	P	S	Ccc/Tcc	2,75	1	0	benign	0,11	neutral	0,34	neutral	2,85	neutral	1,08	neutral	0,74	neutral_impact	0	neutral	0,9	neutral	0,81	deleterious	2,45	19,15	0,25	0,45	NA	NA	neutral	0,05	neutral	0,12	neutral	0,09	8	neutral	0,61	deleterious	0,62	neutral	-6	neutral	0,15	medium_impact	0,1	medium_impact	0,11	low_impact	-1,19	0,35	0,8	26,42	27,76	P	0,69	P	0,55	polymorphism	1	0	.	.	.	.	.	.	.	.	.	C3310T	Diabetes/HCM	+	+	Reported	3
chrM	3310	3310	C	A	MI.10763	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	4	2	P	T	Ccc/Acc	2,75	1	0	benign	0	neutral	0,47	neutral	2,88	neutral	1,52	neutral	0,82	neutral_impact	0	neutral	0,86	neutral	0,79	deleterious	1,98	16,08	0,21	0,45	NA	NA	neutral	0,05	neutral	0,22	neutral	0,1	8	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,07	high_impact	2,07	medium_impact	0,25	low_impact	-1,19	0,5	0,8	26,42	27,76	P	0,53	P	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3310	3310	C	G	MI.10764	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	4	2	P	A	Ccc/Gcc	2,75	1	0	benign	0,11	neutral	0,39	neutral	2,88	neutral	1,48	neutral	0,5	neutral_impact	0	neutral	0,88	neutral	0,75	neutral	1,65	14,15	0,21	0,45	NA	NA	neutral	0,05	neutral	0,24	neutral	0,11	8	neutral	0,55	deleterious	0,64	neutral	-6	neutral	0,12	medium_impact	0,1	medium_impact	0,17	low_impact	-1,19	0,58	0,8	26,42	27,76	P	0,55	P	0,52	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3311	3311	C	A	MI.10765	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	5	2	P	H	cCc/cAc	-1,85	0	0	benign	0,01	neutral	0,34	neutral	2,81	neutral	0,05	neutral	3,08	neutral_impact	0	neutral	0,92	neutral	0,85	deleterious	2,45	19,12	0,16	0,45	NA	NA	neutral	0,09	neutral	0,18	neutral	0,11	8	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,11	low_impact	-1,19	0,36	0,8	26,42	27,76	N	0,5	N	0,55	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3311	3311	C	T	MI.10766	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	5	2	P	L	cCc/cTc	-1,85	0	0	benign	0,01	neutral	1	neutral	2,97	neutral	2,38	neutral	1,03	neutral_impact	0	neutral	0,93	neutral	0,75	deleterious	2,52	19,6	0,18	0,45	NA	NA	neutral	0,1	neutral	0,26	neutral	0,14	7	neutral	0,01	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,12	high_impact	1,96	low_impact	-1,19	0,58	0,8	26,42	27,76	N	0,32	N	0,51	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3311	3311	C	G	MI.10767	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	5	2	P	R	cCc/cGc	-1,85	0	0	benign	0,32	neutral	0,21	neutral	2,81	neutral	0,09	neutral	0,42	neutral_impact	0	neutral	0,83	neutral	0,51	deleterious	2,24	17,79	0,15	0,4	NA	NA	neutral	0,19	neutral	0,34	neutral	0,2	6	neutral	0,75	neutral	0,45	neutral	-6	neutral	0,34	medium_impact	-0,44	medium_impact	-0,05	low_impact	-1,19	0,36	0,8	26,42	27,76	N	0,41	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3313	3313	A	G	MI.10768	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	7	3	M	V	Atg/Gtg	-5,98	0	0	benign	0	neutral	0,67	neutral	2,96	neutral	0,7	neutral	0,28	neutral_impact	0	neutral	0,97	neutral	0,88	neutral	-0,28	0,73	0,32	0,5	NA	NA	neutral	0,14	neutral	0,32	neutral	0,2	6	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,45	low_impact	-1,19	0,18	0,8	30,5	43,29	N	0,32	N	0,3	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3313	3313	A	T	MI.10769	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	7	3	M	L	Atg/Ttg	-5,98	0	0	benign	0,03	neutral	0,9	neutral	3,11	neutral	1,95	neutral	0,56	neutral_impact	0	neutral	0,98	neutral	0,97	neutral	-1,25	0,01	0,24	0,45	NA	NA	neutral	0,06	neutral	0,26	neutral	0,12	8	neutral	0,04	deleterious	0,94	neutral	-6	neutral	0,09	medium_impact	0,67	medium_impact	0,81	low_impact	-1,19	0,22	0,8	30,5	43,29	N	0,4	N	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9032	9032	T	G	MI.1077	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	506	169	L	R	cTa/cGa	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	3,88	deleterious	-5,06	deleterious	-5,27	high_impact	4,37	damaging	0,24	neutral	0,38	deleterious	4,29	24	0,11	0,65	disease	0,89	disease	0,88	disease	0,74	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	high_impact	2,65	0,59	0,9	50,88	8,57	P	0,92	P	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3313	3313	A	C	MI.10770	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	7	3	M	L	Atg/Ctg	-5,98	0	0	benign	0,03	neutral	0,9	neutral	3,11	neutral	1,95	neutral	0,56	neutral_impact	0	neutral	0,98	neutral	0,97	neutral	-1,3	0,01	0,24	0,45	NA	NA	neutral	0,06	neutral	0,26	neutral	0,12	8	neutral	0,04	deleterious	0,94	neutral	-6	neutral	0,09	medium_impact	0,67	medium_impact	0,81	low_impact	-1,19	0,22	0,8	30,5	43,29	N	0,39	N	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3314	3314	T	C	MI.10771	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	8	3	M	T	aTg/aCg	-4,15	0	0	benign	0	neutral	0,49	neutral	2,79	neutral	-0,8	neutral	-1,78	neutral_impact	0	neutral	0,86	neutral	0,79	neutral	-0,28	0,72	0,19	0,45	NA	NA	neutral	0,18	disease	0,53	neutral	0,27	5	neutral	0,51	deleterious	0,75	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,27	low_impact	-1,19	0,08	0,8	30,5	43,29	N	0,35	N	0,04	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3314	3314	T	A	MI.10772	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	8	3	M	K	aTg/aAg	-4,15	0	0	benign	0,11	neutral	0,26	neutral	2,77	neutral	-1,38	deleterious	-3,16	neutral_impact	0	neutral	0,79	neutral	0,48	deleterious	2,05	16,54	0,07	0,35	NA	NA	neutral	0,39	disease	0,61	neutral	0,32	4	neutral	0,7	deleterious	0,58	neutral	-6	neutral	0,23	medium_impact	0,1	medium_impact	0,02	low_impact	-1,19	0,13	0,8	30,5	43,29	N	0,29	N	0,79	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3315	3315	G	C	MI.10773	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	9	3	M	I	atG/atC	-0,01	0	0	benign	0,07	neutral	0,49	neutral	2,92	neutral	0,94	neutral	0,86	neutral_impact	0	neutral	0,95	neutral	0,97	deleterious	-0,02	2,41	0,32	0,5	NA	NA	neutral	0,06	neutral	0,26	neutral	0,14	7	neutral	0,45	deleterious	0,71	neutral	-6	neutral	0,1	medium_impact	0,3	medium_impact	0,27	low_impact	-1,19	0,22	0,8	30,5	43,29	N	0,43	N	0,22	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3315	3315	G	T	MI.10774	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	9	3	M	I	atG/atT	-0,01	0	0	benign	0,07	neutral	0,49	neutral	2,92	neutral	0,94	neutral	0,86	neutral_impact	0	neutral	0,95	neutral	0,97	deleterious	0,08	3,42	0,32	0,5	NA	NA	neutral	0,06	neutral	0,26	neutral	0,14	7	neutral	0,45	deleterious	0,71	neutral	-6	neutral	0,1	medium_impact	0,3	medium_impact	0,27	low_impact	-1,19	0,22	0,8	30,5	43,29	N	0,44	N	0,22	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3316	3316	G	T	MI.10775	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	10	4	A	S	Gcc/Tcc	-3	0	0,04	benign	0,05	neutral	0,47	neutral	2,7	neutral	-1,81	neutral	-0,76	neutral_impact	0,08	neutral	0,85	neutral	0,73	neutral	1,58	13,74	0,26	0,45	NA	NA	neutral	0,08	neutral	0,39	neutral	0,11	8	neutral	0,49	deleterious	0,71	neutral	-6	neutral	0,15	medium_impact	0,45	medium_impact	0,25	low_impact	-1,12	0,39	0,8	22,01	29,35	N	0,38	N	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3316	3316	G	C	MI.10776	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	10	4	A	P	Gcc/Ccc	-3	0	0,04	benign	0,22	neutral	0,23	neutral	2,67	deleterious	-3,28	neutral	-1,62	low_impact	1,32	neutral	0,77	neutral	0,47	neutral	1,74	14,65	0,07	0,35	NA	NA	neutral	0,37	disease	0,62	neutral	0,3	4	neutral	0,73	deleterious	0,51	neutral	-6	neutral	0,32	medium_impact	-0,24	medium_impact	-0,02	medium_impact	-0,04	0,52	0,8	22,01	29,35	N	0,34	N	0,33	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3316	3316	G	A	MI.10777	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	10	4	A	T	Gcc/Acc	-3	0	0,04	benign	0	neutral	0,49	neutral	2,71	neutral	-1,4	neutral	0,05	neutral_impact	-0,76	neutral	0,94	neutral	0,9	neutral	1,04	10,9	0,3	0,45	NA	NA	neutral	0,05	neutral	0,24	neutral	0,12	8	neutral	0,51	deleterious	0,75	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,27	low_impact	-1,85	0,43	0,8	22,01	29,35	N	0,44	N	0,05	polymorphism	1	0,01	rs2853516	.	.	.	.	.	.	.	.	G3316A	Diabetes/LHON/PEO	+	-	Unclear	18
chrM	3317	3317	C	T	MI.10778	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	11	4	A	V	gCc/gTc	-0,01	0	0	benign	0	neutral	0,51	neutral	2,86	neutral	0,47	neutral	2,65	neutral_impact	-0,9	neutral	0,94	neutral	0,96	neutral	0,93	10,27	0,24	0,45	NA	NA	neutral	0,03	neutral	0,19	neutral	0,09	8	neutral	0,49	deleterious	0,76	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,29	low_impact	-1,97	0,64	0,8	22,01	29,35	N	0,36	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3317	3317	C	G	MI.10779	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	11	4	A	G	gCc/gGc	-0,01	0	0	benign	0,05	neutral	0,3	neutral	2,67	neutral	-2,82	neutral	-2,39	neutral_impact	0,52	neutral	0,84	neutral	0,69	deleterious	1,86	15,37	0,26	0,45	NA	NA	neutral	0,09	neutral	0,38	neutral	0,14	7	neutral	0,68	deleterious	0,63	neutral	-6	neutral	0,17	medium_impact	0,45	medium_impact	0,07	medium_impact	-0,73	0,62	0,8	22,01	29,35	N	0,46	N	0,31	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9032	9032	T	A	MI.1078	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	506	169	L	Q	cTa/cAa	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	3,88	deleterious	-5,2	deleterious	-5,25	high_impact	4,37	damaging	0,36	neutral	0,48	deleterious	4,17	23,8	0,12	0,65	disease	0,9	disease	0,84	disease	0,64	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,6	low_impact	-1,4	high_impact	2,65	0,69	0,9	50,88	8,57	P	0,61	P	0,98	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3317	3317	C	A	MI.10780	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	11	4	A	D	gCc/gAc	-0,01	0	0	benign	0,17	neutral	0,21	neutral	2,67	deleterious	-3,38	neutral	-1,9	low_impact	1,32	neutral	0,85	neutral	0,59	deleterious	2,41	18,88	0,04	0,35	NA	NA	neutral	0,3	disease	0,61	neutral	0,28	4	neutral	0,75	deleterious	0,52	neutral	-6	neutral	0,24	medium_impact	-0,1	medium_impact	-0,05	medium_impact	-0,04	0,28	0,8	22,01	29,35	N	0,4	N	0,3	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3319	3319	A	T	MI.10781	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	13	5	N	Y	Aac/Tac	-6,9	0	0	probably_damaging	1	neutral	0,4	neutral	2,7	neutral	-2,55	deleterious	-3,82	medium_impact	2,96	neutral	0,73	neutral	0,38	deleterious	3,64	23,2	0,14	0,4	NA	NA	disease	0,61	disease	0,56	disease	0,64	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,79	low_impact	-3,57	medium_impact	0,18	medium_impact	1,4	0,32	0,8	60,06	9,95	N	0,31	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3319	3319	A	C	MI.10782	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	13	5	N	H	Aac/Cac	-6,9	0	0	probably_damaging	1	neutral	0,21	neutral	2,71	neutral	-1,82	deleterious	-3,17	medium_impact	2,83	neutral	0,75	neutral	0,36	deleterious	2,94	22	0,4	0,5	NA	NA	disease	0,54	disease	0,56	disease	0,54	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,78	low_impact	-3,57	medium_impact	-0,05	medium_impact	1,28	0,19	0,8	60,06	9,95	N	0,37	N	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3319	3319	A	G	MI.10783	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	13	5	N	D	Aac/Gac	-6,9	0	0	probably_damaging	1	neutral	0,19	neutral	2,75	neutral	-0,74	deleterious	-3,93	medium_impact	2,71	neutral	0,73	neutral	0,47	deleterious	3,73	23,3	0,53	0,6	NA	NA	neutral	0,49	disease	0,6	disease	0,62	2	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	-0,08	medium_impact	1,18	0,3	0,8	60,06	9,95	N	0,45	N	0,97	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3320	3320	A	G	MI.10784	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	14	5	N	S	aAc/aGc	3,67	0,99	0	probably_damaging	1	neutral	0,23	neutral	2,81	neutral	0	deleterious	-3,62	low_impact	1,02	neutral	0,84	neutral	0,57	deleterious	3,53	23,1	0,52	0,6	NA	NA	neutral	0,35	neutral	0,4	neutral	0,16	7	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,75	low_impact	-3,57	medium_impact	-0,02	medium_impact	-0,3	0,23	0,8	60,06	9,95	P	0,55	P	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3320	3320	A	C	MI.10785	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	14	5	N	T	aAc/aCc	3,67	0,99	0	probably_damaging	1	neutral	0,29	neutral	2,76	neutral	-0,7	deleterious	-4,07	medium_impact	2,13	neutral	0,83	neutral	0,54	deleterious	3,83	23,4	0,31	0,45	NA	NA	neutral	0,5	disease	0,59	disease	0,61	2	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,77	low_impact	-3,57	medium_impact	0,06	medium_impact	0,67	0,24	0,8	60,06	9,95	P	0,59	P	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3320	3320	A	T	MI.10786	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	14	5	N	I	aAc/aTc	3,67	0,99	0	probably_damaging	1	neutral	0,49	neutral	2,71	neutral	-2,09	deleterious	-5,52	medium_impact	2,19	neutral	0,78	neutral	0,52	deleterious	4,4	24,1	0,15	0,4	NA	NA	disease	0,73	disease	0,58	disease	0,66	3	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,79	low_impact	-3,57	medium_impact	0,27	medium_impact	0,72	0,29	0,8	60,06	9,95	N	0,46	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3321	3321	C	A	MI.10787	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	15	5	N	K	aaC/aaA	5,27	0,99	0	probably_damaging	1	neutral	0,14	neutral	2,84	neutral	0,31	deleterious	-4,46	low_impact	1,52	neutral	0,7	neutral	0,34	deleterious	4,41	24,1	0,45	0,55	NA	NA	disease	0,57	neutral	0,44	neutral	0,44	1	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,79	low_impact	-3,57	medium_impact	-0,17	medium_impact	0,14	0,4	0,8	60,06	9,95	P	0,59	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3321	3321	C	G	MI.10788	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	15	5	N	K	aaC/aaG	5,27	0,99	0	probably_damaging	1	neutral	0,14	neutral	2,84	neutral	0,31	deleterious	-4,46	low_impact	1,52	neutral	0,7	neutral	0,34	deleterious	3,93	23,5	0,45	0,55	NA	NA	disease	0,57	neutral	0,44	neutral	0,44	1	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,79	low_impact	-3,57	medium_impact	-0,17	medium_impact	0,14	0,4	0,8	60,06	9,95	P	0,59	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3322	3322	C	G	MI.10789	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	16	6	L	V	Ctc/Gtc	-3,23	0	0	possibly_damaging	0,45	neutral	0,47	neutral	2,8	neutral	-0,2	neutral	-0,06	neutral_impact	0,78	neutral	0,9	neutral	0,95	neutral	1,08	11,12	0,34	0,5	NA	NA	neutral	0,21	neutral	0,23	neutral	0,19	6	neutral	0,49	deleterious	0,51	neutral	-3	neutral	0,32	medium_impact	-0,67	medium_impact	0,25	medium_impact	-0,51	0,56	0,8	22,96	18,02	N	0,44	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9032	9032	T	C	MI.1079	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	506	169	L	P	cTa/cCa	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	3,87	deleterious	-5,6	deleterious	-6,19	high_impact	4,37	damaging	0,41	neutral	0,5	deleterious	3,98	23,6	0,14	0,65	disease	0,92	disease	0,82	disease	0,74	disease	0,83	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,65	0,63	0,9	50,88	8,57	P	0,62	P	1	disease_causing	0,84	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3322	3322	C	T	MI.10790	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	16	6	L	F	Ctc/Ttc	-3,23	0	0	possibly_damaging	0,9	neutral	0,42	neutral	2,7	neutral	-2,14	neutral	-1,47	low_impact	0,9	neutral	0,88	neutral	0,76	deleterious	2,68	20,7	0,25	0,45	NA	NA	neutral	0,24	neutral	0,25	neutral	0,19	6	neutral	0,89	neutral	0,26	neutral	-3	deleterious	0,69	low_impact	-1,65	medium_impact	0,2	medium_impact	-0,4	0,59	0,8	22,96	18,02	N	0,42	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3322	3322	C	A	MI.10791	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	16	6	L	I	Ctc/Atc	-3,23	0	0	benign	0,1	neutral	0,9	neutral	2,82	neutral	0,48	neutral	-0,33	neutral_impact	-0,12	neutral	0,91	neutral	0,95	deleterious	2,24	17,75	0,33	0,5	NA	NA	neutral	0,17	neutral	0,21	neutral	0,24	5	neutral	0,03	deleterious	0,9	neutral	-6	neutral	0,16	medium_impact	0,15	medium_impact	0,81	low_impact	-1,29	0,46	0,8	22,96	18,02	N	0,29	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3323	3323	T	C	MI.10792	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	17	6	L	P	cTc/cCc	-0,47	0	0	probably_damaging	0,96	neutral	0,06	neutral	2,68	deleterious	-3,73	neutral	3,51	neutral_impact	-0,08	neutral	0,67	neutral	0,66	neutral	1,67	14,25	0,03	0,35	NA	NA	neutral	0,07	neutral	0,47	neutral	0,23	6	deleterious	0,99	neutral	0,05	neutral	-2	deleterious	0,7	low_impact	-2,05	medium_impact	-0,4	low_impact	-1,26	0,11	0,8	22,96	18,02	N	0,47	N	0,96	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3323	3323	T	A	MI.10793	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	17	6	L	H	cTc/cAc	-0,47	0	0	probably_damaging	0,98	neutral	0,16	neutral	2,67	deleterious	-3,92	neutral	-1,25	medium_impact	2,27	neutral	0,76	neutral	0,52	deleterious	4,06	23,7	0,06	0,35	NA	NA	neutral	0,43	neutral	0,49	neutral	0,19	6	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,75	low_impact	-2,34	medium_impact	-0,13	medium_impact	0,79	0,13	0,8	22,96	18,02	N	0,41	N	0,87	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3323	3323	T	G	MI.10794	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	17	6	L	R	cTc/cGc	-0,47	0	0	probably_damaging	0,94	neutral	0,08	neutral	2,69	deleterious	-3,31	neutral	-1,13	medium_impact	2,97	neutral	0,7	neutral	0,48	deleterious	4,08	23,7	0,03	0,35	NA	NA	disease	0,71	disease	0,57	disease	0,73	5	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,81	low_impact	-1,87	medium_impact	-0,32	medium_impact	1,41	0,16	0,8	22,96	18,02	N	0,46	N	0,96	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3325	3325	C	G	MI.10795	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	19	7	L	V	Cta/Gta	-20	0	0	benign	0,21	neutral	0,53	neutral	2,27	neutral	-2,17	neutral	-2,14	medium_impact	2,25	neutral	0,86	neutral	0,3	deleterious	3,36	22,9	0,19	0,45	NA	NA	neutral	0,38	neutral	0,4	neutral	0,17	7	neutral	0,36	deleterious	0,66	neutral	-3	neutral	0,38	medium_impact	-0,21	medium_impact	0,3	medium_impact	0,78	0,56	0,8	54,4	8,9	N	0,25	N	0,6	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3325	3325	C	A	MI.10796	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	19	7	L	M	Cta/Ata	-20	0	0	benign	0,33	neutral	0,29	neutral	2,15	deleterious	-3,64	neutral	-1,33	medium_impact	3	neutral	0,9	neutral	0,71	deleterious	3,66	23,2	0,13	0,4	NA	NA	neutral	0,34	disease	0,52	neutral	0,31	4	neutral	0,65	deleterious	0,48	neutral	-3	neutral	0,38	medium_impact	-0,46	medium_impact	0,06	medium_impact	1,43	0,43	0,8	54,4	8,9	N	0,42	N	0,62	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3326	3326	T	G	MI.10797	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	20	7	L	R	cTa/cGa	-1,16	0	0	probably_damaging	0,91	neutral	0,27	neutral	2,09	deleterious	-5,88	deleterious	-4,65	high_impact	4,2	neutral	0,79	damaging	0,1	deleterious	4,18	23,8	0,02	0,35	NA	NA	disease	0,81	disease	0,73	disease	0,75	5	neutral	0,93	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-1,69	medium_impact	0,03	high_impact	2,48	0,17	0,8	54,4	8,9	N	0,37	N	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3326	3326	T	A	MI.10798	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	20	7	L	Q	cTa/cAa	-1,16	0	0	probably_damaging	0,91	neutral	0,32	neutral	2,09	deleterious	-5,84	deleterious	-4,57	high_impact	3,64	neutral	0,77	damaging	0,14	deleterious	4,05	23,7	0,02	0,35	NA	NA	disease	0,64	disease	0,62	disease	0,68	4	neutral	0,92	neutral	0,21	deleterious	2	deleterious	0,76	low_impact	-1,69	medium_impact	0,09	medium_impact	1,99	0,34	0,8	54,4	8,9	N	0,33	N	0,95	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3326	3326	T	C	MI.10799	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	20	7	L	P	cTa/cCa	-1,16	0	0	probably_damaging	0,95	neutral	0,2	neutral	2,09	deleterious	-6,4	deleterious	-4,8	high_impact	4,2	neutral	0,78	damaging	0,11	deleterious	3,89	23,5	0,02	0,35	NA	NA	disease	0,71	disease	0,74	disease	0,74	5	neutral	0,97	neutral	0,13	deleterious	2	deleterious	0,84	low_impact	-1,95	medium_impact	-0,06	high_impact	2,48	0,28	0,8	54,4	8,9	N	0,38	N	0,93	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8576	8576	T	C	MI.108	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	50	17	L	P	cTa/cCa	-0,57	0	0	probably_damaging	1	deleterious	0,04	neutral	4,4	deleterious	-4,86	deleterious	-4,75	medium_impact	2,22	neutral	0,76	neutral	0,32	deleterious	3,69	23,3	0,17	0,65	disease	0,91	disease	0,9	disease	0,67	disease	0,83	7	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,9	low_impact	-3,6	medium_impact	-0,49	medium_impact	0,81	0,63	0,9	28,76	21,22	N	0,25	N	0,88	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9034	9034	C	T	MI.1080	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	508	170	L	F	Ctc/Ttc	-8,66	0	0	probably_damaging	1	deleterious	0,01	neutral	3,87	deleterious	-3,2	deleterious	-3,52	high_impact	4,1	neutral	0,6	damaging	0,15	deleterious	4,05	23,7	0,36	0,65	disease	0,82	disease	0,74	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,6	medium_impact	-0,84	high_impact	2,42	0,59	0,9	48,67	8,89	N	0,28	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3328	3328	C	G	MI.10800	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	22	8	L	V	Ctc/Gtc	-0,93	0	0	benign	0,04	neutral	0,55	neutral	2,73	neutral	-0,86	neutral	-0,41	low_impact	1,74	neutral	0,91	neutral	0,86	deleterious	1,9	15,62	0,27	0,45	NA	NA	neutral	0,27	neutral	0,23	neutral	0,18	6	neutral	0,4	deleterious	0,76	neutral	-6	neutral	0,16	medium_impact	0,55	medium_impact	0,32	medium_impact	0,33	0,44	0,8	19,18	28,55	N	0,33	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3328	3328	C	T	MI.10801	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	22	8	L	F	Ctc/Ttc	-0,93	0	0	possibly_damaging	0,84	neutral	0,7	neutral	2,63	neutral	-1,98	neutral	-1,7	low_impact	1,66	neutral	0,87	neutral	0,79	deleterious	2,45	19,17	0,27	0,45	NA	NA	neutral	0,3	neutral	0,25	neutral	0,18	6	neutral	0,81	neutral	0,43	neutral	-3	deleterious	0,68	low_impact	-1,43	medium_impact	0,48	medium_impact	0,26	0,38	0,8	19,18	28,55	N	0,33	N	0,31	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3328	3328	C	A	MI.10802	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	22	8	L	I	Ctc/Atc	-0,93	0	0	benign	0,33	neutral	0,84	neutral	2,73	neutral	-0,95	neutral	-0,49	low_impact	1,43	neutral	0,82	neutral	0,73	deleterious	2,44	19,07	0,27	0,45	NA	NA	neutral	0,24	neutral	0,16	neutral	0,18	6	neutral	0,22	deleterious	0,76	neutral	-6	neutral	0,31	medium_impact	-0,46	medium_impact	0,68	medium_impact	0,06	0,31	0,8	19,18	28,55	N	0,31	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3329	3329	T	G	MI.10803	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	23	8	L	R	cTc/cGc	-3,92	0	0	probably_damaging	0,91	neutral	0,21	neutral	2,62	deleterious	-3,74	neutral	-2,12	high_impact	3,75	neutral	0,77	neutral	0,48	deleterious	2,86	21,7	0,03	0,35	NA	NA	disease	0,76	disease	0,61	disease	0,74	5	neutral	0,94	neutral	0,15	deleterious	2	deleterious	0,8	low_impact	-1,69	medium_impact	-0,05	high_impact	2,09	0,16	0,8	19,18	28,55	N	0,4	N	0,62	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3329	3329	T	A	MI.10804	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	23	8	L	H	cTc/cAc	-3,92	0	0	probably_damaging	0,97	neutral	0,56	neutral	2,6	deleterious	-4,31	deleterious	-2,75	medium_impact	2,87	neutral	0,77	neutral	0,56	deleterious	2,94	22	0,06	0,35	NA	NA	disease	0,54	neutral	0,48	neutral	0,5	0	neutral	0,96	neutral	0,3	deleterious	1	deleterious	0,74	low_impact	-2,17	medium_impact	0,33	medium_impact	1,32	0,17	0,8	19,18	28,55	N	0,27	N	0,63	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3329	3329	T	C	MI.10805	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	23	8	L	P	cTc/cCc	-3,92	0	0	probably_damaging	0,93	neutral	0,18	neutral	2,6	deleterious	-4,04	neutral	-2,26	medium_impact	3,41	neutral	0,81	neutral	0,43	deleterious	3,65	23,2	0,04	0,35	NA	NA	disease	0,74	disease	0,62	disease	0,73	5	neutral	0,96	neutral	0,13	deleterious	1	deleterious	0,78	low_impact	-1,81	medium_impact	-0,09	medium_impact	1,79	0,22	0,8	19,18	28,55	N	0,34	N	0,87	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3331	3331	C	G	MI.10806	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	25	9	L	V	Ctc/Gtc	-4,38	0	0	benign	0,03	neutral	0,44	neutral	2,58	neutral	-1,35	neutral	-0,59	low_impact	1,2	neutral	0,94	neutral	0,94	deleterious	2,09	16,81	0,33	0,5	NA	NA	disease	0,51	neutral	0,27	neutral	0,47	1	neutral	0,53	deleterious	0,71	neutral	-6	neutral	0,19	medium_impact	0,67	medium_impact	0,22	medium_impact	-0,14	0,49	0,8	23,58	29,46	N	0,36	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3331	3331	C	T	MI.10807	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	25	9	L	F	Ctc/Ttc	-4,38	0	0	possibly_damaging	0,73	neutral	0,38	neutral	2,51	neutral	-2,2	neutral	1,16	low_impact	1,46	neutral	0,88	neutral	0,93	deleterious	2,36	18,58	0,3	0,45	NA	NA	neutral	0,43	neutral	0,28	neutral	0,23	5	neutral	0,75	neutral	0,33	neutral	-3	deleterious	0,65	low_impact	-1,16	medium_impact	0,16	medium_impact	0,09	0,37	0,8	23,58	29,46	N	0,43	N	0,32	polymorphism	1	0,02	rs878932147	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3331	3331	C	A	MI.10808	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	25	9	L	I	Ctc/Atc	-4,38	0	0	benign	0,04	neutral	1	neutral	2,65	neutral	-0,84	neutral	-0,36	low_impact	1,02	neutral	0,91	neutral	0,81	deleterious	3,79	23,4	0,29	0,45	NA	NA	disease	0,51	neutral	0,23	neutral	0,44	1	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,19	medium_impact	0,55	high_impact	1,96	medium_impact	-0,3	0,31	0,8	23,58	29,46	N	0,26	N	0,44	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3332	3332	T	A	MI.10809	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	26	9	L	H	cTc/cAc	-0,24	0	0	probably_damaging	0,96	neutral	0,15	neutral	2,43	deleterious	-4,61	neutral	-0,74	medium_impact	2,94	neutral	0,72	neutral	0,52	deleterious	3,86	23,5	0,07	0,35	NA	NA	disease	0,72	disease	0,59	disease	0,72	4	neutral	0,98	neutral	0,1	deleterious	1	deleterious	0,77	low_impact	-2,05	medium_impact	-0,15	medium_impact	1,38	0,14	0,8	23,58	29,46	N	0,42	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9034	9034	C	G	MI.1081	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	508	170	L	V	Ctc/Gtc	-8,66	0	0	probably_damaging	0,99	neutral	0,08	neutral	4,04	neutral	-1,47	deleterious	-2,64	medium_impact	2,44	damaging	0,58	damaging	0,17	deleterious	3,51	23,1	0,32	0,65	neutral	0,42	disease	0,59	disease	0,62	disease	0,57	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,74	low_impact	-2,65	medium_impact	-0,31	medium_impact	0,99	0,63	0,9	48,67	8,89	N	0,29	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3332	3332	T	G	MI.10810	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	26	9	L	R	cTc/cGc	-0,24	0	0	possibly_damaging	0,88	neutral	0,07	neutral	2,44	deleterious	-3,99	neutral	-2,33	medium_impact	3,49	neutral	0,68	neutral	0,46	deleterious	3,94	23,5	0,04	0,35	NA	NA	disease	0,89	disease	0,64	disease	0,79	6	neutral	0,97	neutral	0,1	NA	0	deleterious	0,82	low_impact	-1,56	medium_impact	-0,35	medium_impact	1,86	0,19	0,8	23,58	29,46	N	0,46	N	0,92	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3332	3332	T	C	MI.10811	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	26	9	L	P	cTc/cCc	-0,24	0	0	probably_damaging	0,91	neutral	0,08	neutral	2,43	deleterious	-4,62	deleterious	-2,64	medium_impact	2,25	neutral	0,62	neutral	0,33	deleterious	3,67	23,3	0,04	0,35	NA	NA	disease	0,86	disease	0,65	disease	0,79	6	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,8	low_impact	-1,69	medium_impact	-0,32	medium_impact	0,78	0,15	0,8	23,58	29,46	N	0,32	N	0,92	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3334	3334	A	G	MI.10812	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	28	10	I	V	Att/Gtt	-6,67	0	0	benign	0,01	neutral	0,51	neutral	2,55	neutral	-1,3	neutral	-0,75	medium_impact	2,12	neutral	0,89	neutral	0,91	neutral	-0,16	1,32	0,41	0,5	NA	NA	neutral	0,32	neutral	0,34	neutral	0,16	7	neutral	0,48	deleterious	0,75	neutral	-3	neutral	0,14	medium_impact	1,12	medium_impact	0,29	medium_impact	0,66	0,25	0,8	20,75	32,42	N	0,38	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3334	3334	A	T	MI.10813	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	28	10	I	F	Att/Ttt	-6,67	0	0	possibly_damaging	0,69	neutral	0,55	neutral	2,39	deleterious	-3,31	deleterious	-2,99	low_impact	1,93	neutral	0,71	neutral	0,47	neutral	1,75	14,69	0,15	0,4	NA	NA	disease	0,72	neutral	0,37	disease	0,51	0	neutral	0,65	neutral	0,43	neutral	-3	deleterious	0,63	low_impact	-1,08	medium_impact	0,32	medium_impact	0,5	0,31	0,8	20,75	32,42	N	0,32	N	0,87	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3334	3334	A	C	MI.10814	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	28	10	I	L	Att/Ctt	-6,67	0	0	benign	0,09	neutral	1	neutral	2,74	neutral	-0,27	neutral	-1,26	low_impact	1,46	neutral	0,89	neutral	0,89	deleterious	0,53	7,64	0,2	0,45	NA	NA	disease	0,58	neutral	0,28	neutral	0,45	1	neutral	0,09	deleterious	0,96	neutral	-6	neutral	0,21	medium_impact	0,19	high_impact	1,96	medium_impact	0,09	0,35	0,8	20,75	32,42	N	0,26	N	0,11	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3335	3335	T	G	MI.10815	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	29	10	I	S	aTt/aGt	0,45	0	0,01	benign	0,3	neutral	0,35	neutral	2,36	deleterious	-4,36	deleterious	-4,65	medium_impact	2,34	neutral	0,86	neutral	0,47	deleterious	2,12	17,01	0,06	0,35	NA	NA	disease	0,8	disease	0,55	disease	0,69	4	neutral	0,58	deleterious	0,53	neutral	-3	neutral	0,38	medium_impact	-0,41	medium_impact	0,12	medium_impact	0,86	0,23	0,8	20,75	32,42	N	0,33	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3335	3335	T	C	MI.10816	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	29	10	I	T	aTt/aCt	0,45	0	0,01	benign	0,01	neutral	0,22	neutral	2,38	deleterious	-3,69	deleterious	-3,87	medium_impact	2,58	neutral	0,87	neutral	0,91	neutral	1,18	11,67	0,14	0,4	NA	NA	disease	0,64	neutral	0,39	neutral	0,49	0	neutral	0,77	deleterious	0,61	neutral	-3	neutral	0,19	medium_impact	1,12	medium_impact	-0,03	medium_impact	1,07	0,2	0,8	20,75	32,42	N	0,46	N	0,98	polymorphism	1	0,11	rs879173824	.	.	.	.	.	.	.	.	T3335C	LHON (putative)	+	-	Reported	1
chrM	3335	3335	T	A	MI.10817	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	29	10	I	N	aTt/aAt	0,45	0	0,01	possibly_damaging	0,54	neutral	0,38	neutral	2,35	deleterious	-5,41	deleterious	-5,51	high_impact	4,07	neutral	0,76	neutral	0,4	deleterious	2,28	18,02	0,1	0,4	NA	NA	disease	0,78	disease	0,59	disease	0,69	4	neutral	0,62	neutral	0,42	deleterious	1	deleterious	0,57	medium_impact	-0,82	medium_impact	0,16	high_impact	2,37	0,27	0,8	20,75	32,42	N	0,39	N	0,98	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3336	3336	T	G	MI.10818	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	30	10	I	M	atT/atG	1,83	0,01	0,03	possibly_damaging	0,76	neutral	0,2	neutral	2,49	neutral	-1,79	neutral	-1,87	low_impact	1,57	neutral	0,84	neutral	0,8	deleterious	0,41	6,69	0,28	0,45	NA	NA	disease	0,51	neutral	0,31	neutral	0,43	1	neutral	0,86	neutral	0,22	neutral	-3	deleterious	0,58	low_impact	-1,22	medium_impact	-0,06	medium_impact	0,18	0,39	0,8	20,75	32,42	N	0,45	N	0,43	polymorphism	1	0,04	rs28416101	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3336	3336	T	A	MI.10819	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	30	10	I	M	atT/atA	1,83	0,01	0,03	possibly_damaging	0,76	neutral	0,2	neutral	2,49	neutral	-1,79	neutral	-1,87	low_impact	1,57	neutral	0,84	neutral	0,8	deleterious	0,75	9,15	0,28	0,45	NA	NA	disease	0,51	neutral	0,31	neutral	0,43	1	neutral	0,86	neutral	0,22	neutral	-3	deleterious	0,58	low_impact	-1,22	medium_impact	-0,06	medium_impact	0,18	0,39	0,8	20,75	32,42	N	0,42	N	0,43	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9034	9034	C	A	MI.1082	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	508	170	L	I	Ctc/Atc	-8,66	0	0	probably_damaging	0,99	neutral	0,27	neutral	4,06	neutral	-1,37	neutral	-1,76	medium_impact	2,56	neutral	0,63	damaging	0,17	deleterious	4,18	23,8	0,3	0,65	disease	0,5	disease	0,64	neutral	0,41	neutral	0,46	1	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,77	low_impact	-2,65	medium_impact	0,05	medium_impact	1,1	0,75	0,9	48,67	8,89	N	0,32	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3337	3337	G	C	MI.10820	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	31	11	V	L	Gta/Cta	-5,07	0	0	benign	0	neutral	1	neutral	2,79	neutral	-0,08	neutral	-1,26	neutral_impact	-0,39	neutral	0,91	neutral	0,93	deleterious	0,04	2,99	0,22	0,45	NA	NA	disease	0,65	neutral	0,27	neutral	0,45	1	neutral	0	deleterious	1	neutral	-6	neutral	0,16	high_impact	2,07	high_impact	1,96	low_impact	-1,53	0,18	0,8	22,01	23,44	N	0,25	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3337	3337	G	A	MI.10821	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	31	11	V	M	Gta/Ata	-5,07	0	0	benign	0,03	neutral	0,31	neutral	2,51	neutral	-2,9	neutral	-1,84	low_impact	0,96	neutral	0,91	neutral	0,65	neutral	1,44	13,01	0,14	0,4	NA	NA	disease	0,71	neutral	0,44	disease	0,52	0	neutral	0,67	deleterious	0,64	neutral	-6	neutral	0,16	medium_impact	0,67	medium_impact	0,08	medium_impact	-0,35	0,46	0,8	22,01	23,44	N	0,34	N	0,05	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	G3337A	Cardiomyopathy	+	-	Possibly synergistic	1
chrM	3337	3337	G	T	MI.10822	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	31	11	V	L	Gta/Tta	-5,07	0	0	benign	0	neutral	1	neutral	2,79	neutral	-0,08	neutral	-1,26	neutral_impact	-0,39	neutral	0,91	neutral	0,93	deleterious	0,19	4,62	0,22	0,45	NA	NA	disease	0,65	neutral	0,27	neutral	0,45	1	neutral	0	deleterious	1	neutral	-6	neutral	0,16	high_impact	2,07	high_impact	1,96	low_impact	-1,53	0,18	0,8	22,01	23,44	N	0,25	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3338	3338	T	G	MI.10823	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	32	11	V	G	gTa/gGa	-3	0	0,01	benign	0,21	neutral	0,29	neutral	2,47	deleterious	-4,46	deleterious	-5,73	low_impact	1,66	neutral	0,74	neutral	0,4	neutral	1,61	13,91	0,06	0,35	NA	NA	disease	0,8	disease	0,56	disease	0,73	5	neutral	0,65	deleterious	0,54	neutral	-6	neutral	0,3	medium_impact	-0,21	medium_impact	0,06	medium_impact	0,26	0,32	0,8	22,01	23,44	N	0,35	N	0,78	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3338	3338	T	C	MI.10824	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	32	11	V	A	gTa/gCa	-3	0	0,01	benign	0,01	neutral	0,5	neutral	2,56	neutral	-1,87	deleterious	-3,16	neutral_impact	0,08	neutral	0,95	neutral	0,93	deleterious	0,14	4	0,12	0,4	NA	NA	disease	0,51	neutral	0,36	neutral	0,45	1	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,16	medium_impact	1,12	medium_impact	0,28	low_impact	-1,12	0,08	0,8	22,01	23,44	N	0,29	N	0,49	polymorphism	1	0,1	rs201969351	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3338	3338	T	A	MI.10825	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	32	11	V	E	gTa/gAa	-3	0	0,01	benign	0,28	neutral	0,23	neutral	2,48	deleterious	-4,25	deleterious	-4,94	medium_impact	2,86	neutral	0,8	neutral	0,32	deleterious	2,47	19,26	0,03	0,35	NA	NA	disease	0,91	disease	0,67	disease	0,8	6	neutral	0,72	deleterious	0,48	neutral	-3	neutral	0,41	medium_impact	-0,37	medium_impact	-0,02	medium_impact	1,31	0,15	0,8	22,01	23,44	N	0,32	N	0,88	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3340	3340	C	A	MI.10826	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	34	12	P	T	Ccc/Acc	-12,42	0	0	possibly_damaging	0,46	neutral	0,3	neutral	2,75	neutral	-1,24	deleterious	-6,11	medium_impact	3,21	neutral	0,74	neutral	0,39	neutral	1,55	13,55	0,21	0,45	NA	NA	disease	0,74	neutral	0,43	disease	0,51	0	neutral	0,66	neutral	0,42	NA	0	deleterious	0,51	medium_impact	-0,69	medium_impact	0,07	medium_impact	1,62	0,44	0,8	21,07	20,74	N	0,42	N	0,74	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3340	3340	C	T	MI.10827	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	34	12	P	S	Ccc/Tcc	-12,42	0	0	benign	0,04	neutral	0,26	neutral	2,75	neutral	-1,22	deleterious	-6,07	low_impact	1,26	neutral	0,76	neutral	0,63	neutral	1,66	14,17	0,19	0,45	NA	NA	disease	0,73	neutral	0,31	disease	0,5	0	neutral	0,72	deleterious	0,61	neutral	-6	neutral	0,23	medium_impact	0,55	medium_impact	0,02	medium_impact	-0,09	0,24	0,8	21,07	20,74	N	0,41	N	0,28	polymorphism	1	0,12	.	.	.	.	.	.	.	CPD	2,97	C3340T	Encephaloneuromyopathy	+	-	Reported	1
chrM	3340	3340	C	G	MI.10828	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	34	12	P	A	Ccc/Gcc	-12,42	0	0	benign	0,23	neutral	0,31	neutral	2,79	neutral	-0,15	deleterious	-6,12	medium_impact	2,6	neutral	0,8	neutral	0,44	neutral	0,93	10,23	0,2	0,45	NA	NA	disease	0,66	neutral	0,4	disease	0,51	0	neutral	0,63	deleterious	0,54	neutral	-3	neutral	0,37	medium_impact	-0,26	medium_impact	0,08	medium_impact	1,08	0,52	0,8	21,07	20,74	N	0,37	N	0,6	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3341	3341	C	G	MI.10829	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	35	12	P	R	cCc/cGc	1,14	0,07	0	possibly_damaging	0,82	neutral	0,2	neutral	2,71	neutral	-2,61	deleterious	-7,03	high_impact	3,67	neutral	0,76	neutral	0,39	neutral	1,54	13,53	0,08	0,35	NA	NA	disease	0,93	disease	0,66	disease	0,79	6	neutral	0,89	neutral	0,19	deleterious	1	deleterious	0,8	low_impact	-1,37	medium_impact	-0,06	high_impact	2,02	0,36	0,8	21,07	20,74	N	0,45	N	0,94	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9035	9035	T	A	MI.1083	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	509	170	L	H	cTc/cAc	-1,72	0	0	probably_damaging	1	deleterious	0	neutral	3,81	deleterious	-5,89	deleterious	-6,17	high_impact	4,45	damaging	0,47	damaging	0,14	deleterious	4,32	24	0,16	0,65	disease	0,92	disease	0,82	disease	0,71	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,72	0,52	0,9	48,67	8,89	N	0,4	N	0,97	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3341	3341	C	T	MI.10830	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	35	12	P	L	cCc/cTc	1,14	0,07	0	possibly_damaging	0,59	neutral	1	neutral	2,78	neutral	-0,34	deleterious	-7,56	medium_impact	2,25	neutral	0,75	neutral	0,39	deleterious	2,25	17,86	0,13	0,4	NA	NA	disease	0,89	neutral	0,43	disease	0,67	3	neutral	0,59	deleterious	0,71	NA	0	deleterious	0,56	medium_impact	-0,9	high_impact	1,96	medium_impact	0,78	0,5	0,8	21,07	20,74	N	0,28	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3341	3341	C	A	MI.10831	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	35	12	P	H	cCc/cAc	1,14	0,07	0	probably_damaging	0,92	neutral	0,31	neutral	2,69	deleterious	-3,28	deleterious	-6,85	high_impact	4,02	neutral	0,78	neutral	0,31	deleterious	3,56	23,1	0,11	0,4	NA	NA	disease	0,87	disease	0,64	disease	0,73	5	neutral	0,94	neutral	0,2	deleterious	2	deleterious	0,81	low_impact	-1,75	medium_impact	0,08	high_impact	2,32	0,26	0,8	21,07	20,74	N	0,4	N	0,88	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3343	3343	A	T	MI.10832	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	37	13	I	F	Att/Ttt	-11,96	0	0	benign	0,17	neutral	0,21	neutral	2,47	deleterious	-3,47	deleterious	-3,54	medium_impact	3	neutral	0,75	neutral	0,34	deleterious	1,86	15,35	0,16	0,45	NA	NA	disease	0,81	neutral	0,49	disease	0,69	4	neutral	0,75	deleterious	0,52	neutral	-3	neutral	0,3	medium_impact	-0,1	medium_impact	-0,05	medium_impact	1,43	0,28	0,8	22,96	30,5	N	0,39	N	0,86	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3343	3343	A	C	MI.10833	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	37	13	I	L	Att/Ctt	-11,96	0	0	benign	0,01	neutral	1	neutral	2,62	neutral	-1,05	neutral	-1,76	medium_impact	2,04	neutral	0,76	neutral	0,54	neutral	1,67	14,23	0,19	0,45	NA	NA	disease	0,65	neutral	0,29	neutral	0,47	1	neutral	0,01	deleterious	1	neutral	-3	neutral	0,18	medium_impact	1,12	high_impact	1,96	medium_impact	0,59	0,32	0,8	22,96	30,5	N	0,24	N	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3343	3343	A	G	MI.10834	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	37	13	I	V	Att/Gtt	-11,96	0	0	benign	0	neutral	0,3	neutral	3	neutral	0,71	neutral	-0,18	low_impact	0,82	neutral	0,94	neutral	0,96	neutral	-1,43	0	0,32	0,5	NA	NA	neutral	0,08	neutral	0,23	neutral	0,23	5	neutral	0,7	deleterious	0,65	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,07	medium_impact	-0,47	0,28	0,8	22,96	30,5	P	0,54	P	0,55	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3344	3344	T	C	MI.10835	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	38	13	I	T	aTt/aCt	1,6	0,87	0	benign	0	neutral	0,13	neutral	2,48	deleterious	-3,02	deleterious	-3,7	medium_impact	2,59	neutral	0,92	neutral	0,62	deleterious	0,07	3,27	0,15	0,4	NA	NA	disease	0,6	disease	0,55	disease	0,61	2	neutral	0,87	deleterious	0,57	neutral	-3	neutral	0,17	high_impact	2,07	medium_impact	-0,19	medium_impact	1,07	0,24	0,8	22,96	30,5	N	0,42	N	0,58	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3344	3344	T	G	MI.10836	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	38	13	I	S	aTt/aGt	1,6	0,87	0	benign	0,05	neutral	0,21	neutral	2,47	deleterious	-3,68	deleterious	-4,94	medium_impact	2,67	neutral	0,75	neutral	0,37	deleterious	2,14	17,14	0,09	0,35	NA	NA	disease	0,81	disease	0,56	disease	0,73	5	neutral	0,77	deleterious	0,58	neutral	-3	neutral	0,22	medium_impact	0,45	medium_impact	-0,05	medium_impact	1,14	0,2	0,8	22,96	30,5	N	0,4	N	0,88	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3344	3344	T	A	MI.10837	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	38	13	I	N	aTt/aAt	1,6	0,87	0	benign	0,13	deleterious	0,04	neutral	2,45	deleterious	-4,71	deleterious	-5,84	high_impact	3,75	neutral	0,76	neutral	0,36	deleterious	2,22	17,64	0,16	0,45	NA	NA	disease	0,83	disease	0,57	disease	0,75	5	neutral	0,96	neutral	0,46	deleterious	2	neutral	0,28	medium_impact	0,02	medium_impact	-0,5	high_impact	2,09	0,2	0,8	22,96	30,5	N	0,46	N	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3345	3345	T	G	MI.10838	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	39	13	I	M	atT/atG	4,58	0,95	0	benign	0,38	neutral	0,31	neutral	2,48	deleterious	-3,21	neutral	-2,3	medium_impact	2,94	neutral	0,75	neutral	0,34	neutral	1,27	12,13	0,34	0,5	NA	NA	disease	0,67	disease	0,56	disease	0,69	4	neutral	0,63	neutral	0,47	neutral	-3	neutral	0,33	medium_impact	-0,55	medium_impact	0,08	medium_impact	1,38	0,38	0,8	22,96	30,5	N	0,53	P	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3345	3345	T	A	MI.10839	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	39	13	I	M	atT/atA	4,58	0,95	0	benign	0,38	neutral	0,31	neutral	2,48	deleterious	-3,21	neutral	-2,3	medium_impact	2,94	neutral	0,75	neutral	0,34	neutral	1,62	13,98	0,34	0,5	NA	NA	disease	0,67	disease	0,56	disease	0,69	4	neutral	0,63	neutral	0,47	neutral	-3	neutral	0,33	medium_impact	-0,55	medium_impact	0,08	medium_impact	1,38	0,38	0,8	22,96	30,5	P	0,54	P	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9035	9035	T	G	MI.1084	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	509	170	L	R	cTc/cGc	-1,72	0	0	probably_damaging	1	deleterious	0	neutral	3,81	deleterious	-5,31	deleterious	-5,29	high_impact	4,45	damaging	0,37	damaging	0,13	deleterious	4,25	23,9	0,16	0,65	disease	0,89	disease	0,88	disease	0,74	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	high_impact	2,72	0,51	0,9	48,67	8,89	P	0,56	P	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3346	3346	C	G	MI.10840	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	40	14	L	V	Cta/Gta	-8,28	0	0	benign	0,3	neutral	0,61	neutral	2,61	neutral	-1,51	deleterious	-2,57	medium_impact	3,19	neutral	0,68	neutral	0,37	deleterious	3,17	22,7	0,32	0,5	NA	NA	disease	0,58	disease	0,6	disease	0,65	3	neutral	0,3	deleterious	0,66	neutral	-3	neutral	0,4	medium_impact	-0,41	medium_impact	0,38	medium_impact	1,6	0,47	0,8	20,75	16,16	N	0,28	N	0,84	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3346	3346	C	A	MI.10841	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	40	14	L	M	Cta/Ata	-8,28	0	0	benign	0,25	neutral	0,21	neutral	2,49	neutral	-2,23	neutral	-1,68	medium_impact	2,81	neutral	0,82	neutral	0,61	deleterious	3,44	23	0,25	0,45	NA	NA	neutral	0,48	neutral	0,5	neutral	0,32	4	neutral	0,75	deleterious	0,48	neutral	-3	neutral	0,27	medium_impact	-0,3	medium_impact	-0,05	medium_impact	1,27	0,31	0,8	20,75	16,16	N	0,37	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3347	3347	T	A	MI.10842	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	41	14	L	Q	cTa/cAa	-1,16	0	0	probably_damaging	0,94	neutral	0,08	neutral	2,42	deleterious	-4,62	deleterious	-5,22	high_impact	4,29	neutral	0,7	neutral	0,34	deleterious	3,75	23,3	0,07	0,35	NA	NA	disease	0,76	disease	0,62	disease	0,68	4	deleterious	0,98	neutral	0,07	deleterious	2	deleterious	0,81	low_impact	-1,87	medium_impact	-0,32	high_impact	2,56	0,2	0,8	20,75	16,16	N	0,46	N	0,99	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3347	3347	T	C	MI.10843	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	41	14	L	P	cTa/cCa	-1,16	0	0	probably_damaging	0,97	neutral	0,1	neutral	2,4	deleterious	-4,79	deleterious	-6,08	high_impact	4,64	neutral	0,63	neutral	0,29	deleterious	3,64	23,2	0,05	0,35	NA	NA	disease	0,79	disease	0,72	disease	0,73	5	deleterious	0,99	neutral	0,07	deleterious	2	deleterious	0,88	low_impact	-2,17	medium_impact	-0,26	high_impact	2,86	0,2	0,8	20,75	16,16	N	0,47	N	1	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3347	3347	T	G	MI.10844	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	41	14	L	R	cTa/cGa	-1,16	0	0	probably_damaging	0,94	neutral	0,05	neutral	2,42	deleterious	-4,47	deleterious	-5,24	high_impact	4,64	neutral	0,7	damaging	0,25	deleterious	3,87	23,5	0,04	0,35	NA	NA	disease	0,89	disease	0,73	disease	0,79	6	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,88	low_impact	-1,87	medium_impact	-0,44	high_impact	2,86	0,13	0,8	20,75	16,16	P	0,54	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3349	3349	A	G	MI.10845	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	43	15	I	V	Atc/Gtc	-6,21	0	0	benign	0,01	neutral	0,59	neutral	2,81	neutral	0,07	neutral	-0,74	neutral_impact	0,62	neutral	0,95	neutral	0,97	neutral	1,62	13,99	0,38	0,5	NA	NA	neutral	0,18	neutral	0,22	neutral	0,21	6	neutral	0,4	deleterious	0,79	neutral	-6	neutral	0,12	medium_impact	1,12	medium_impact	0,36	medium_impact	-0,65	0,3	0,8	27,36	46,43	N	0,39	N	0,6	polymorphism	1	0,02	rs879193727	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3349	3349	A	T	MI.10846	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	43	15	I	F	Atc/Ttc	-6,21	0	0	possibly_damaging	0,44	neutral	0,36	neutral	2,67	neutral	-1,46	neutral	-2,25	medium_impact	2,57	neutral	0,86	neutral	0,5	deleterious	3,56	23,1	0,15	0,4	NA	NA	disease	0,65	disease	0,52	disease	0,6	2	neutral	0,59	neutral	0,46	NA	0	neutral	0,41	medium_impact	-0,65	medium_impact	0,14	medium_impact	1,06	0,25	0,8	27,36	46,43	N	0,33	N	0,57	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3349	3349	A	C	MI.10847	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	43	15	I	L	Atc/Ctc	-6,21	0	0	benign	0,01	neutral	1	neutral	2,86	neutral	0,42	neutral	0,81	neutral_impact	-0,58	neutral	0,84	neutral	0,93	deleterious	0,76	9,21	0,24	0,45	NA	NA	neutral	0,16	neutral	0,19	neutral	0,23	5	neutral	0,01	deleterious	1	neutral	-6	neutral	0,1	medium_impact	1,12	high_impact	1,96	low_impact	-1,7	0,2	0,8	27,36	46,43	N	0,32	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3350	3350	T	A	MI.10848	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	44	15	I	N	aTc/aAc	-0,7	0	0	possibly_damaging	0,52	deleterious	0,03	neutral	2,66	deleterious	-3,59	deleterious	-4,84	medium_impact	2,92	neutral	0,72	neutral	0,41	deleterious	4,33	24	0,11	0,4	NA	NA	disease	0,72	disease	0,51	disease	0,59	2	neutral	0,97	neutral	0,26	deleterious	4	deleterious	0,57	medium_impact	-0,78	medium_impact	-0,57	medium_impact	1,36	0,19	0,8	27,36	46,43	N	0,4	N	0,83	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3350	3350	T	C	MI.10849	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	44	15	I	T	aTc/aCc	-0,7	0	0	benign	0,01	deleterious	0,04	neutral	2,72	neutral	-1,45	deleterious	-3	medium_impact	2,23	neutral	0,8	neutral	0,59	deleterious	3,22	22,7	0,18	0,45	NA	NA	neutral	0,42	neutral	0,49	neutral	0,2	6	neutral	0,96	deleterious	0,52	deleterious	1	neutral	0,15	medium_impact	1,12	medium_impact	-0,5	medium_impact	0,76	0,19	0,8	27,36	46,43	N	0,43	N	0,55	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9035	9035	T	C	MI.1085	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	509	170	L	P	cTc/cCc	-1,72	0	0	probably_damaging	1	deleterious	0	neutral	3,81	deleterious	-5,85	deleterious	-6,22	high_impact	4,45	damaging	0,28	damaging	0,15	deleterious	4,03	23,7	0,17	0,65	disease	0,92	disease	0,82	disease	0,74	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,72	0,69	0,9	48,67	8,89	P	0,78	P	1	disease_causing	0,99	0,32	.	.	.	.	.	.	.	.	.	T9035C	Ataxia syndrome	+	-	Reported	2
chrM	3350	3350	T	G	MI.10850	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	44	15	I	S	aTc/aGc	-0,7	0	0	benign	0,22	neutral	0,24	neutral	2,69	neutral	-2,09	deleterious	-3,94	medium_impact	3,12	neutral	0,74	neutral	0,45	deleterious	4,07	23,7	0,07	0,35	NA	NA	disease	0,68	disease	0,51	disease	0,57	1	neutral	0,71	deleterious	0,51	neutral	-3	neutral	0,29	medium_impact	-0,24	medium_impact	-0,01	medium_impact	1,54	0,22	0,8	27,36	46,43	N	0,43	N	0,59	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3351	3351	C	G	MI.10851	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	45	15	I	M	atC/atG	5,5	0,86	0	possibly_damaging	0,55	neutral	0,18	neutral	2,67	neutral	-1,67	neutral	-0,61	low_impact	1,68	neutral	0,86	neutral	0,63	deleterious	3,15	22,6	0,3	0,45	NA	NA	neutral	0,47	neutral	0,38	neutral	0,33	3	neutral	0,81	neutral	0,32	neutral	-3	deleterious	0,53	medium_impact	-0,83	medium_impact	-0,09	medium_impact	0,28	0,31	0,8	27,36	46,43	P	0,51	P	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3351	3351	C	A	MI.10852	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	45	15	I	M	atC/atA	5,5	0,86	0	possibly_damaging	0,55	neutral	0,18	neutral	2,67	neutral	-1,67	neutral	-0,61	low_impact	1,68	neutral	0,86	neutral	0,63	deleterious	3,63	23,2	0,3	0,45	NA	NA	neutral	0,47	neutral	0,38	neutral	0,33	3	neutral	0,81	neutral	0,32	neutral	-3	deleterious	0,53	medium_impact	-0,83	medium_impact	-0,09	medium_impact	0,28	0,31	0,8	27,36	46,43	P	0,51	P	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3352	3352	G	T	MI.10853	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	46	16	A	S	Gca/Tca	-3,23	0	0	probably_damaging	1	neutral	0,14	neutral	2,82	neutral	-1,55	deleterious	-2,64	low_impact	1,74	neutral	0,73	damaging	0,13	deleterious	3,48	23,1	0,28	0,45	NA	NA	disease	0,61	neutral	0,24	neutral	0,42	2	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,82	low_impact	-3,57	medium_impact	-0,17	medium_impact	0,33	0,34	0,8	59,12	10,11	N	0,36	N	0,93	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3352	3352	G	A	MI.10854	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	46	16	A	T	Gca/Aca	-3,23	0	0	probably_damaging	1	neutral	0,1	neutral	2,66	neutral	-1,93	deleterious	-3,54	medium_impact	2,71	neutral	0,69	damaging	0,1	deleterious	4,01	23,6	0,24	0,45	NA	NA	disease	0,74	disease	0,52	disease	0,57	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,83	low_impact	-3,57	medium_impact	-0,26	medium_impact	1,18	0,62	0,8	59,12	10,11	N	0,37	N	0,7	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3352	3352	G	C	MI.10855	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	46	16	A	P	Gca/Cca	-3,23	0	0	probably_damaging	1	neutral	0,17	neutral	2,6	deleterious	-3,67	deleterious	-4,44	high_impact	3,56	neutral	0,71	damaging	0,1	deleterious	3,61	23,2	0,08	0,35	NA	NA	disease	0,9	disease	0,65	disease	0,73	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	-0,11	medium_impact	1,92	0,46	0,8	59,12	10,11	N	0,37	N	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3353	3353	C	T	MI.10856	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	47	16	A	V	gCa/gTa	5,04	1	0	probably_damaging	1	neutral	0,64	neutral	2,64	neutral	-1,33	deleterious	-3,56	medium_impact	2,69	neutral	0,68	damaging	0,1	deleterious	4,26	23,9	0,21	0,45	NA	NA	disease	0,85	disease	0,51	disease	0,69	4	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,87	low_impact	-3,57	medium_impact	0,42	medium_impact	1,16	0,55	0,8	59,12	10,11	N	0,52	P	0,72	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3353	3353	C	G	MI.10857	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	47	16	A	G	gCa/gGa	5,04	1	0	probably_damaging	1	neutral	0,07	neutral	2,73	neutral	-1,75	deleterious	-3,55	medium_impact	2,02	neutral	0,84	damaging	0,15	deleterious	3,74	23,3	0,28	0,45	NA	NA	disease	0,61	neutral	0,24	neutral	0,42	2	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,8	low_impact	-3,57	medium_impact	-0,35	medium_impact	0,58	0,61	0,8	59,12	10,11	N	0,53	P	0,79	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3353	3353	C	A	MI.10858	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	47	16	A	E	gCa/gAa	5,04	1	0	probably_damaging	1	deleterious	0,03	neutral	2,68	deleterious	-3,22	deleterious	-4,43	high_impact	3,91	neutral	0,76	damaging	0,12	deleterious	4,28	24	0,08	0,35	NA	NA	disease	0,9	disease	0,64	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,89	low_impact	-3,57	medium_impact	-0,57	high_impact	2,23	0,29	0,8	59,12	10,11	P	0,56	P	0,96	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3355	3355	A	T	MI.10859	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	49	17	M	L	Atg/Ttg	-6,44	0	0	probably_damaging	0,98	neutral	0,71	neutral	2,94	neutral	1,74	neutral	-0,35	low_impact	1,03	neutral	0,68	neutral	0,61	deleterious	3,12	22,6	0,27	0,45	NA	NA	disease	0,7	neutral	0,45	disease	0,53	1	deleterious	0,98	neutral	0,37	neutral	-2	deleterious	0,84	low_impact	-2,34	medium_impact	0,49	medium_impact	-0,29	0,26	0,8	23,58	36,17	N	0,35	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9037	9037	A	G	MI.1086	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	511	171	M	V	Atg/Gtg	-6,35	0	0	possibly_damaging	0,87	neutral	0,1	neutral	4,52	neutral	0,18	neutral	-0,49	low_impact	1,76	neutral	0,8	neutral	0,6	deleterious	2,79	21,3	0,27	0,65	neutral	0,3	disease	0,75	neutral	0,48	disease	0,55	1	neutral	0,96	neutral	0,12	neutral	-3	deleterious	0,57	low_impact	-1,54	medium_impact	-0,25	medium_impact	0,41	0,55	0,9	17,26	16,43	N	0,31	N	0,55	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3355	3355	A	G	MI.10860	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	49	17	M	V	Atg/Gtg	-6,44	0	0	probably_damaging	0,99	neutral	1	neutral	3,27	neutral	3,32	neutral	1,71	neutral_impact	-2,11	neutral	0,74	neutral	0,96	neutral	-0,27	0,79	0,31	0,5	NA	NA	neutral	0,21	neutral	0,3	neutral	0,16	7	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,7	low_impact	-2,62	high_impact	1,96	low_impact	-3,03	0,27	0,8	23,58	36,17	N	0,25	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3355	3355	A	C	MI.10861	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	49	17	M	L	Atg/Ctg	-6,44	0	0	probably_damaging	0,98	neutral	0,71	neutral	2,94	neutral	1,74	neutral	-0,35	low_impact	1,03	neutral	0,68	neutral	0,61	deleterious	3,06	22,4	0,27	0,45	NA	NA	disease	0,7	neutral	0,45	disease	0,53	1	deleterious	0,98	neutral	0,37	neutral	-2	deleterious	0,84	low_impact	-2,34	medium_impact	0,49	medium_impact	-0,29	0,26	0,8	23,58	36,17	N	0,35	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3356	3356	T	C	MI.10862	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	50	17	M	T	aTg/aCg	5,04	1	0	probably_damaging	1	neutral	0,09	neutral	2,81	neutral	0,07	neutral	-1,31	low_impact	1,53	neutral	0,63	neutral	0,72	deleterious	2,73	21	0,16	0,45	NA	NA	disease	0,6	neutral	0,49	neutral	0,48	0	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,84	low_impact	-3,57	medium_impact	-0,29	medium_impact	0,15	0,14	0,8	23,58	36,17	P	0,63	P	0,74	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3356	3356	T	A	MI.10863	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	50	17	M	K	aTg/aAg	5,04	1	0	probably_damaging	1	neutral	0,09	neutral	2,78	neutral	-0,83	deleterious	-2,96	medium_impact	2,5	neutral	0,64	neutral	0,47	deleterious	3,86	23,5	0,06	0,35	NA	NA	disease	0,88	disease	0,63	disease	0,81	6	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,9	low_impact	-3,57	medium_impact	-0,29	medium_impact	1	0,2	0,8	23,58	36,17	P	0,61	P	0,95	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3357	3357	G	C	MI.10864	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	51	17	M	I	atG/atC	7,34	1	0	probably_damaging	0,99	neutral	0,55	neutral	2,98	neutral	2,04	neutral	0,96	neutral_impact	0,13	neutral	0,78	neutral	0,57	deleterious	3,28	22,8	0,31	0,45	NA	NA	disease	0,71	neutral	0,45	disease	0,52	0	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,86	low_impact	-2,62	medium_impact	0,32	low_impact	-1,08	0,29	0,8	23,58	36,17	N	0,46	N	0,48	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3357	3357	G	T	MI.10865	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	51	17	M	I	atG/atT	7,34	1	0	probably_damaging	0,99	neutral	0,55	neutral	2,98	neutral	2,04	neutral	0,96	neutral_impact	0,13	neutral	0,78	neutral	0,57	deleterious	3,39	23	0,31	0,45	NA	NA	disease	0,71	neutral	0,45	disease	0,52	0	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,86	low_impact	-2,62	medium_impact	0,32	low_impact	-1,08	0,29	0,8	23,58	36,17	N	0,47	N	0,48	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3358	3358	G	A	MI.10866	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	52	18	A	T	Gca/Aca	-0,93	0,07	0	probably_damaging	1	neutral	0,28	neutral	2,5	neutral	-2,63	deleterious	-3,54	medium_impact	3,41	neutral	0,71	neutral	0,46	deleterious	4,02	23,6	0,16	0,45	NA	NA	disease	0,83	disease	0,54	disease	0,7	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,9	low_impact	-3,57	medium_impact	0,05	medium_impact	1,79	0,58	0,8	60,38	9,95	N	0,48	N	0,7	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3358	3358	G	T	MI.10867	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	52	18	A	S	Gca/Tca	-0,93	0,07	0	probably_damaging	1	neutral	0,37	neutral	2,5	neutral	-2,68	deleterious	-2,65	high_impact	3,56	neutral	0,68	neutral	0,53	deleterious	3,48	23,1	0,24	0,45	NA	NA	disease	0,84	disease	0,51	disease	0,65	3	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	0,15	medium_impact	1,92	0,39	0,8	60,38	9,95	N	0,45	N	0,93	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3358	3358	G	C	MI.10868	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	52	18	A	P	Gca/Cca	-0,93	0,07	0	probably_damaging	1	neutral	0,41	neutral	2,45	deleterious	-4,34	deleterious	-4,44	high_impact	4,76	neutral	0,67	neutral	0,41	deleterious	3,61	23,2	0,05	0,35	NA	NA	disease	0,91	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,93	low_impact	-3,57	medium_impact	0,19	high_impact	2,97	0,48	0,8	60,38	9,95	P	0,72	P	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3359	3359	C	G	MI.10869	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	53	18	A	G	gCa/gGa	7,11	1	0	probably_damaging	1	neutral	0,3	neutral	2,46	deleterious	-3,67	deleterious	-3,55	medium_impact	3,17	neutral	0,8	neutral	0,53	deleterious	3,74	23,3	0,28	0,45	NA	NA	disease	0,82	disease	0,52	disease	0,51	0	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,88	low_impact	-3,57	medium_impact	0,07	medium_impact	1,58	0,6	0,8	60,38	9,95	P	0,58	P	0,79	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9037	9037	A	T	MI.1087	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	511	171	M	L	Atg/Ttg	-6,35	0	0	possibly_damaging	0,81	neutral	0,84	neutral	4,65	neutral	2,27	neutral	-0,56	neutral_impact	0,53	neutral	0,84	neutral	0,82	deleterious	2,3	18,16	0,25	0,65	neutral	0,26	disease	0,62	neutral	0,43	neutral	0,47	1	neutral	0,78	deleterious	0,52	neutral	-3	deleterious	0,53	low_impact	-1,35	medium_impact	0,7	medium_impact	-0,64	0,54	0,9	17,26	16,43	N	0,26	N	0,58	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3359	3359	C	A	MI.10870	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	53	18	A	E	gCa/gAa	7,11	1	0	probably_damaging	1	neutral	0,17	neutral	2,48	deleterious	-3,21	deleterious	-4,43	high_impact	4,76	neutral	0,72	neutral	0,41	deleterious	4,23	23,9	0,05	0,35	NA	NA	disease	0,92	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,92	low_impact	-3,57	medium_impact	-0,11	high_impact	2,97	0,2	0,8	60,38	9,95	P	0,76	P	0,96	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3359	3359	C	T	MI.10871	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	53	18	A	V	gCa/gTa	7,11	1	0	probably_damaging	1	neutral	0,75	neutral	2,59	neutral	-1,39	deleterious	-3,56	medium_impact	3,48	neutral	0,65	neutral	0,45	deleterious	4,3	24	0,14	0,4	NA	NA	disease	0,9	disease	0,61	disease	0,71	4	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,92	low_impact	-3,57	medium_impact	0,54	medium_impact	1,85	0,57	0,8	60,38	9,95	P	0,6	P	0,72	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3361	3361	T	G	MI.10872	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	55	19	F	V	Ttc/Gtc	-4,61	0	0	probably_damaging	1	neutral	1	neutral	2,71	neutral	-0,54	deleterious	-5,61	medium_impact	3,36	neutral	0,71	damaging	0,15	deleterious	3,94	23,5	0,12	0,4	NA	NA	disease	0,92	disease	0,62	disease	0,73	5	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,88	low_impact	-3,57	high_impact	1,96	medium_impact	1,75	0,17	0,8	60,06	10,21	N	0,3	N	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3361	3361	T	A	MI.10873	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	55	19	F	I	Ttc/Atc	-4,61	0	0	probably_damaging	1	neutral	0,46	neutral	2,62	neutral	-1,24	deleterious	-4,72	high_impact	3,64	neutral	0,76	damaging	0,19	deleterious	4,22	23,9	0,17	0,45	NA	NA	disease	0,9	disease	0,57	disease	0,68	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,24	medium_impact	1,99	0,3	0,8	60,06	10,21	N	0,42	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3361	3361	T	C	MI.10874	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	55	19	F	L	Ttc/Ctc	-4,61	0	0	probably_damaging	1	neutral	0,77	neutral	2,79	neutral	-0,08	deleterious	-4,6	medium_impact	3	neutral	0,82	damaging	0,22	deleterious	3,81	23,4	0,2	0,45	NA	NA	disease	0,83	neutral	0,44	disease	0,51	0	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,84	low_impact	-3,57	medium_impact	0,57	medium_impact	1,43	0,57	0,8	60,06	10,21	N	0,29	N	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3362	3362	T	C	MI.10875	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	56	19	F	S	tTc/tCc	4,35	1	0	probably_damaging	1	neutral	0,21	neutral	2,5	deleterious	-3,35	deleterious	-6,68	high_impact	4,13	neutral	0,76	damaging	0,18	deleterious	4,1	23,7	0,04	0,35	NA	NA	disease	0,9	disease	0,61	disease	0,72	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	-0,05	high_impact	2,42	0,17	0,8	60,06	10,21	P	0,59	P	0,98	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3362	3362	T	G	MI.10876	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	56	19	F	C	tTc/tGc	4,35	1	0	probably_damaging	1	neutral	0,07	neutral	2,48	deleterious	-4,57	deleterious	-6,6	high_impact	4,68	neutral	0,76	damaging	0,15	deleterious	3,91	23,5	0,05	0,35	NA	NA	disease	0,88	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,35	high_impact	2,9	0,15	0,8	60,06	10,21	P	0,61	P	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3362	3362	T	A	MI.10877	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	56	19	F	Y	tTc/tAc	4,35	1	0	probably_damaging	1	neutral	0,15	neutral	2,5	deleterious	-3,37	deleterious	-2,52	medium_impact	2,37	neutral	0,85	damaging	0,18	deleterious	4,21	23,9	0,2	0,45	NA	NA	disease	0,77	neutral	0,44	disease	0,5	0	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,85	low_impact	-3,57	medium_impact	-0,15	medium_impact	0,88	0,48	0,8	60,06	10,21	N	0,54	P	0,88	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3363	3363	C	G	MI.10878	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	57	19	F	L	ttC/ttG	4,58	1	0	probably_damaging	1	neutral	0,77	neutral	2,79	neutral	-0,08	deleterious	-4,6	medium_impact	3	neutral	0,82	damaging	0,22	deleterious	4,14	23,8	0,2	0,45	NA	NA	disease	0,83	neutral	0,44	disease	0,51	0	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,84	low_impact	-3,57	medium_impact	0,57	medium_impact	1,43	0,57	0,8	60,06	10,21	N	0,44	N	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3363	3363	C	A	MI.10879	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	57	19	F	L	ttC/ttA	4,58	1	0	probably_damaging	1	neutral	0,77	neutral	2,79	neutral	-0,08	deleterious	-4,6	medium_impact	3	neutral	0,82	damaging	0,22	deleterious	4,46	24,2	0,2	0,45	NA	NA	disease	0,83	neutral	0,44	disease	0,51	0	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,84	low_impact	-3,57	medium_impact	0,57	medium_impact	1,43	0,57	0,8	60,06	10,21	N	0,44	N	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9037	9037	A	C	MI.1088	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	511	171	M	L	Atg/Ctg	-6,35	0	0	possibly_damaging	0,81	neutral	0,84	neutral	4,65	neutral	2,27	neutral	-0,56	neutral_impact	0,53	neutral	0,84	neutral	0,82	deleterious	2,29	18,08	0,25	0,65	neutral	0,26	disease	0,62	neutral	0,43	neutral	0,47	1	neutral	0,78	deleterious	0,52	neutral	-3	deleterious	0,53	low_impact	-1,35	medium_impact	0,7	medium_impact	-0,64	0,54	0,9	17,26	16,43	N	0,26	N	0,58	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3364	3364	C	G	MI.10880	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	58	20	L	V	Cta/Gta	-3,23	0	0	possibly_damaging	0,86	neutral	0,44	neutral	2,39	neutral	-1,71	deleterious	-2,56	medium_impact	2,9	neutral	0,66	damaging	0,07	deleterious	3,22	22,7	0,31	0,45	NA	NA	disease	0,7	neutral	0,35	neutral	0,5	0	neutral	0,85	neutral	0,29	NA	0	deleterious	0,81	low_impact	-1,49	medium_impact	0,22	medium_impact	1,34	0,44	0,8	60,38	10,28	N	0,26	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3364	3364	C	A	MI.10881	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	58	20	L	M	Cta/Ata	-3,23	0	0	probably_damaging	0,98	neutral	0,06	neutral	2,29	neutral	-2,65	neutral	-1,66	medium_impact	2,85	neutral	0,66	damaging	0,08	deleterious	3,52	23,1	0,27	0,45	NA	NA	disease	0,68	neutral	0,47	neutral	0,47	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,82	low_impact	-2,34	medium_impact	-0,4	medium_impact	1,3	0,37	0,8	60,38	10,28	N	0,3	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3365	3365	T	G	MI.10882	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	59	20	L	R	cTa/cGa	0,68	0,26	0	probably_damaging	0,98	deleterious	0,04	neutral	2,18	deleterious	-5,48	deleterious	-5,17	high_impact	4,46	damaging	0,5	damaging	0,05	deleterious	3,96	23,6	0,02	0,35	NA	NA	disease	0,93	disease	0,71	disease	0,82	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,94	low_impact	-2,34	medium_impact	-0,5	high_impact	2,71	0,16	0,8	60,38	10,28	N	0,46	N	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3365	3365	T	A	MI.10883	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	59	20	L	Q	cTa/cAa	0,68	0,26	0	probably_damaging	0,99	deleterious	0,04	neutral	2,18	deleterious	-5,47	deleterious	-5,17	high_impact	4,46	damaging	0,54	damaging	0,06	deleterious	3,89	23,5	0,04	0,35	NA	NA	disease	0,85	disease	0,59	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,87	low_impact	-2,62	medium_impact	-0,5	high_impact	2,71	0,18	0,8	60,38	10,28	N	0,42	N	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3365	3365	T	C	MI.10884	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	59	20	L	P	cTa/cCa	0,68	0,26	0	probably_damaging	0,99	neutral	0,08	neutral	2,18	deleterious	-6,02	deleterious	-6,07	high_impact	4,46	damaging	0,44	damaging	0,06	deleterious	3,72	23,3	0,02	0,35	NA	NA	disease	0,89	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,93	low_impact	-2,62	medium_impact	-0,32	high_impact	2,71	0,21	0,8	60,38	10,28	P	0,51	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3367	3367	A	G	MI.10885	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	61	21	M	V	Atg/Gtg	-16,09	0	0	benign	0,02	neutral	0,5	neutral	3,04	neutral	2,19	neutral	0,76	neutral_impact	-2,02	neutral	0,61	neutral	0,69	deleterious	2,47	19,25	0,23	0,45	NA	NA	disease	0,71	neutral	0,39	disease	0,51	0	neutral	0,48	deleterious	0,74	neutral	-6	neutral	0,29	medium_impact	0,84	medium_impact	0,28	low_impact	-2,95	0,22	0,8	54,4	10	N	0,35	N	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3367	3367	A	C	MI.10886	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	61	21	M	L	Atg/Ctg	-16,09	0	0	benign	0,02	neutral	1	neutral	2,87	neutral	1,7	neutral	-0,08	neutral_impact	-0,98	neutral	0,63	neutral	0,55	deleterious	3,07	22,5	0,21	0,45	NA	NA	disease	0,69	neutral	0,45	neutral	0,49	0	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,29	medium_impact	0,84	high_impact	1,96	low_impact	-2,04	0,22	0,8	54,4	10	N	0,28	N	0,48	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3367	3367	A	T	MI.10887	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	61	21	M	L	Atg/Ttg	-16,09	0	0	benign	0,02	neutral	1	neutral	2,87	neutral	1,7	neutral	-0,08	neutral_impact	-0,98	neutral	0,63	neutral	0,55	deleterious	3,09	22,5	0,21	0,45	NA	NA	disease	0,69	neutral	0,45	neutral	0,49	0	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,29	medium_impact	0,84	high_impact	1,96	low_impact	-2,04	0,22	0,8	54,4	10	N	0,28	N	0,48	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3368	3368	T	C	MI.10888	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	62	21	M	T	aTg/aCg	8,49	1	0,01	benign	0	neutral	0,33	neutral	3,03	neutral	2,2	neutral	5,02	neutral_impact	-4,74	neutral	0,69	neutral	0,75	deleterious	0,09	3,48	0,15	0,4	NA	NA	neutral	0,12	neutral	0,27	neutral	0,18	6	neutral	0,67	deleterious	0,67	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,1	low_impact	-5,33	0,12	0,8	54,4	10	P	0,57	P	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3368	3368	T	A	MI.10889	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	62	21	M	K	aTg/aAg	8,49	1	0,01	benign	0,11	neutral	0,05	neutral	2,82	neutral	-0,52	neutral	-0,16	neutral_impact	0	neutral	0,62	neutral	0,5	deleterious	3,93	23,5	0,06	0,35	NA	NA	disease	0,85	disease	0,57	disease	0,76	5	neutral	0,94	deleterious	0,47	neutral	-6	neutral	0,39	medium_impact	0,1	medium_impact	-0,44	low_impact	-1,19	0,19	0,8	54,4	10	P	0,6	P	0,63	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9038	9038	T	C	MI.1089	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	512	171	M	T	aTg/aCg	5,68	1	0	probably_damaging	0,94	deleterious	0	neutral	4,34	neutral	-1,27	deleterious	-3,25	medium_impact	2,31	neutral	0,84	neutral	0,59	deleterious	3,02	22,3	0,23	0,65	disease	0,69	disease	0,76	disease	0,62	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,77	low_impact	-1,89	low_impact	-1,4	medium_impact	0,88	0,46	0,9	17,26	16,43	N	0,45	N	0,87	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3369	3369	G	T	MI.10890	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	63	21	M	I	atG/atT	3,44	0,99	0	benign	0	neutral	0,32	neutral	2,87	neutral	1,7	neutral	-0,11	neutral_impact	-1,94	neutral	0,82	neutral	0,57	deleterious	3,39	23	0,27	0,45	NA	NA	disease	0,71	neutral	0,39	neutral	0,49	0	neutral	0,68	deleterious	0,66	neutral	-6	neutral	0,3	high_impact	2,07	medium_impact	0,09	low_impact	-2,88	0,3	0,8	54,4	10	N	0,36	N	0,42	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3369	3369	G	C	MI.10891	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	63	21	M	I	atG/atC	3,44	0,99	0	benign	0	neutral	0,32	neutral	2,87	neutral	1,7	neutral	-0,11	neutral_impact	-1,94	neutral	0,82	neutral	0,57	deleterious	3,25	22,8	0,27	0,45	NA	NA	disease	0,71	neutral	0,39	neutral	0,49	0	neutral	0,68	deleterious	0,66	neutral	-6	neutral	0,3	high_impact	2,07	medium_impact	0,09	low_impact	-2,88	0,3	0,8	54,4	10	N	0,35	N	0,42	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3370	3370	C	G	MI.10892	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	64	22	L	V	Ctt/Gtt	-11,27	0	0	probably_damaging	1	neutral	1	neutral	2,4	neutral	-2,56	deleterious	-2,68	medium_impact	3,24	neutral	0,79	damaging	0,16	deleterious	3,22	22,7	0,29	0,45	NA	NA	disease	0,77	disease	0,61	disease	0,67	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,89	low_impact	-3,57	high_impact	1,96	medium_impact	1,64	0,61	0,8	59,75	10,36	N	0,17	N	0,84	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3370	3370	C	T	MI.10893	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	64	22	L	F	Ctt/Ttt	-11,27	0	0	probably_damaging	1	neutral	0,69	neutral	2,46	neutral	-1,89	deleterious	-3,57	medium_impact	3,24	neutral	0,66	damaging	0,13	deleterious	3,76	23,3	0,14	0,4	NA	NA	disease	0,79	disease	0,55	disease	0,67	3	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,89	low_impact	-3,57	medium_impact	0,47	medium_impact	1,64	0,56	0,8	59,75	10,36	N	0,25	N	0,95	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3370	3370	C	A	MI.10894	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	64	22	L	I	Ctt/Att	-11,27	0	0	probably_damaging	1	neutral	0,57	neutral	2,4	neutral	-2,64	neutral	-1,79	medium_impact	3	neutral	0,76	damaging	0,16	deleterious	3,93	23,5	0,33	0,5	NA	NA	disease	0,8	disease	0,6	disease	0,68	4	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,89	low_impact	-3,57	medium_impact	0,34	medium_impact	1,43	0,48	0,8	59,75	10,36	N	0,26	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3371	3371	T	G	MI.10895	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	65	22	L	R	cTt/cGt	-2,54	0	0	probably_damaging	1	neutral	0,05	neutral	2,33	deleterious	-4,49	deleterious	-5,36	high_impact	4,71	neutral	0,72	damaging	0,11	deleterious	4	23,6	0,02	0,35	NA	NA	disease	0,94	disease	0,73	disease	0,85	7	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,94	low_impact	-3,57	medium_impact	-0,44	high_impact	2,93	0,19	0,8	59,75	10,36	P	0,61	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3371	3371	T	A	MI.10896	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	65	22	L	H	cTt/cAt	-2,54	0	0	probably_damaging	1	neutral	0,07	neutral	2,33	deleterious	-4,34	deleterious	-6,25	high_impact	4,71	neutral	0,71	damaging	0,12	deleterious	3,9	23,5	0,04	0,35	NA	NA	disease	0,86	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	-0,35	high_impact	2,93	0,23	0,8	59,75	10,36	P	0,59	P	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3371	3371	T	C	MI.10897	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	65	22	L	P	cTt/cCt	-2,54	0	0	probably_damaging	1	deleterious	0,03	neutral	2,32	deleterious	-5,21	deleterious	-6,25	high_impact	4,71	neutral	0,72	damaging	0,13	deleterious	3,69	23,3	0,02	0,35	NA	NA	disease	0,87	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,94	low_impact	-3,57	medium_impact	-0,57	high_impact	2,93	0,24	0,8	59,75	10,36	P	0,56	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3373	3373	A	T	MI.10898	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	67	23	T	S	Acc/Tcc	-3,69	0	0	benign	0,18	neutral	0,14	neutral	2,79	neutral	-0,93	neutral	-1,22	neutral_impact	0,6	neutral	0,68	neutral	0,63	deleterious	3,1	22,5	0,37	0,5	NA	NA	neutral	0,48	neutral	0,33	neutral	0,35	3	neutral	0,84	deleterious	0,48	neutral	-6	neutral	0,28	medium_impact	-0,13	medium_impact	-0,17	medium_impact	-0,66	0,7	0,85	27,04	28,71	N	0,45	N	0,27	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3373	3373	A	G	MI.10899	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	67	23	T	A	Acc/Gcc	-3,69	0	0	benign	0,01	neutral	0,79	neutral	2,86	neutral	1,5	neutral	-0,08	neutral_impact	-0,42	neutral	0,9	neutral	0,92	deleterious	2,21	17,6	0,26	0,45	NA	NA	neutral	0,38	neutral	0,14	neutral	0,17	7	neutral	0,18	deleterious	0,89	neutral	-6	neutral	0,18	medium_impact	1,12	medium_impact	0,6	low_impact	-1,56	0,41	0,8	27,04	28,71	N	0,4	N	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8576	8576	T	G	MI.109	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	50	17	L	R	cTa/cGa	-0,57	0	0	probably_damaging	1	deleterious	0,02	neutral	4,41	deleterious	-4,15	deleterious	-4,38	medium_impact	2,77	neutral	0,83	neutral	0,39	deleterious	3,99	23,6	0,18	0,65	disease	0,88	disease	0,91	disease	0,73	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,9	low_impact	-3,6	medium_impact	-0,66	medium_impact	1,28	0,66	0,9	28,76	21,22	N	0,29	N	0,77	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9038	9038	T	A	MI.1090	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	512	171	M	K	aTg/aAg	5,68	1	0	probably_damaging	0,94	deleterious	0	neutral	4,3	neutral	-2,77	deleterious	-4,31	medium_impact	2,94	neutral	0,77	neutral	0,42	deleterious	4,14	23,8	0,11	0,65	disease	0,83	disease	0,9	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,84	low_impact	-1,89	low_impact	-1,4	medium_impact	1,42	0,45	0,9	17,26	16,43	N	0,47	N	0,95	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3373	3373	A	C	MI.10900	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	67	23	T	P	Acc/Ccc	-3,69	0	0	possibly_damaging	0,62	neutral	0,09	neutral	2,74	neutral	-2,49	neutral	-1,93	low_impact	1,7	neutral	0,63	neutral	0,46	deleterious	3,28	22,8	0,04	0,35	NA	NA	disease	0,88	neutral	0,48	disease	0,79	6	neutral	0,91	neutral	0,24	neutral	-3	deleterious	0,75	medium_impact	-0,95	medium_impact	-0,29	medium_impact	0,3	0,38	0,8	27,04	28,71	N	0,39	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3374	3374	C	A	MI.10901	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	68	23	T	N	aCc/aAc	-2,31	0	0	possibly_damaging	0,62	neutral	0,08	neutral	2,75	neutral	-1,71	neutral	-2,2	low_impact	1,7	damaging	0,59	neutral	0,62	deleterious	3,43	23	0,19	0,45	NA	NA	disease	0,71	neutral	0,34	disease	0,5	0	neutral	0,92	neutral	0,23	neutral	-3	deleterious	0,69	medium_impact	-0,95	medium_impact	-0,32	medium_impact	0,3	0,61	0,8	27,04	28,71	N	0,41	N	0,75	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3374	3374	C	T	MI.10902	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	68	23	T	I	aCc/aTc	-2,31	0	0	benign	0,01	neutral	0,2	neutral	2,85	neutral	1,2	neutral	2,31	neutral_impact	-1,26	neutral	0,87	neutral	0,96	neutral	1,7	14,41	0,09	0,35	NA	NA	disease	0,53	neutral	0,14	neutral	0,42	2	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,2	medium_impact	1,12	medium_impact	-0,06	low_impact	-2,29	0,59	0,8	27,04	28,71	N	0,45	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3374	3374	C	G	MI.10903	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	68	23	T	S	aCc/aGc	-2,31	0	0	benign	0,18	neutral	0,14	neutral	2,79	neutral	-0,93	neutral	-1,22	neutral_impact	0,6	neutral	0,68	neutral	0,63	deleterious	3,3	22,9	0,37	0,5	NA	NA	neutral	0,48	neutral	0,33	neutral	0,35	3	neutral	0,84	deleterious	0,48	neutral	-6	neutral	0,28	medium_impact	-0,13	medium_impact	-0,17	medium_impact	-0,66	0,7	0,85	27,04	28,71	N	0,44	N	0,27	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3376	3376	G	A	MI.10904	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	70	24	E	K	Gaa/Aaa	-5,75	0	0	probably_damaging	1	neutral	0,09	neutral	2,17	deleterious	-3,5	deleterious	-3,56	high_impact	4,17	neutral	0,72	damaging	0,14	deleterious	4,29	24	0,04	0,35	NA	NA	disease	0,94	disease	0,65	disease	0,76	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,94	low_impact	-3,57	medium_impact	-0,29	high_impact	2,45	0,54	0,8	59,12	10,27	N	0,5	N	0,99	disease_causing_automatic	0	0,46	rs397515612	Pathogenic	Leber's_optic_atrophy	RCV000056167.1	MedGen:OMIM:SNOMED_CT	.	.	.	.	G3376A	LHON MELAS overlap	+	+	Cfrm	3
chrM	3376	3376	G	C	MI.10905	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	70	24	E	Q	Gaa/Caa	-5,75	0	0	probably_damaging	1	neutral	0,09	neutral	2,16	deleterious	-3,74	deleterious	-2,67	high_impact	4,51	neutral	0,68	damaging	0,14	deleterious	3,19	22,7	0,1	0,4	NA	NA	disease	0,83	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	-0,29	high_impact	2,75	0,7	0,85	59,12	10,27	N	0,48	N	0,91	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3377	3377	A	G	MI.10906	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	71	24	E	G	gAa/gGa	7,11	1	0	probably_damaging	1	neutral	0,13	neutral	2,14	deleterious	-4,15	deleterious	-6,24	high_impact	4,51	neutral	0,68	damaging	0,17	deleterious	4,18	23,8	0,03	0,35	NA	NA	disease	0,86	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	-0,19	high_impact	2,75	0,28	0,8	59,12	10,27	P	0,65	P	0,61	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3377	3377	A	C	MI.10907	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	71	24	E	A	gAa/gCa	7,11	1	0	probably_damaging	1	neutral	0,69	neutral	2,15	deleterious	-3,76	deleterious	-5,35	high_impact	4,86	neutral	0,69	damaging	0,16	deleterious	3,51	23,1	0,04	0,35	NA	NA	disease	0,81	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	0,47	high_impact	3,06	0,32	0,8	59,12	10,27	P	0,71	P	0,74	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3377	3377	A	T	MI.10908	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	71	24	E	V	gAa/gTa	7,11	1	0	probably_damaging	1	neutral	0,61	neutral	2,11	deleterious	-5,16	deleterious	-6,24	high_impact	4,86	neutral	0,64	damaging	0,13	deleterious	4,14	23,8	0,02	0,35	NA	NA	disease	0,93	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,93	low_impact	-3,57	medium_impact	0,38	high_impact	3,06	0,24	0,8	59,12	10,27	P	0,69	P	0,83	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3378	3378	A	T	MI.10909	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	72	24	E	D	gaA/gaT	8,49	1	0	probably_damaging	1	neutral	0,07	neutral	2,29	neutral	-2,07	deleterious	-2,68	high_impact	3,82	neutral	0,77	damaging	0,15	deleterious	3,62	23,2	0,22	0,45	NA	NA	disease	0,84	disease	0,55	disease	0,69	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	-0,35	high_impact	2,15	0,55	0,8	59,12	10,27	P	0,61	P	0,9	polymorphism	0,99	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9039	9039	G	C	MI.1091	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	513	171	M	I	atG/atC	5,68	1	0,01	probably_damaging	0,91	neutral	1	neutral	4,48	neutral	0,57	neutral	0,03	neutral_impact	-0,4	neutral	0,81	neutral	0,97	neutral	0,9	10,05	0,3	0,65	neutral	0,35	neutral	0,2	neutral	0,35	neutral	0,35	3	neutral	0,91	deleterious	0,55	neutral	-2	deleterious	0,6	low_impact	-1,71	high_impact	1,98	low_impact	-1,44	0,64	0,9	17,26	16,43	N	0,47	N	0,05	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3378	3378	A	C	MI.10910	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	72	24	E	D	gaA/gaC	8,49	1	0	probably_damaging	1	neutral	0,07	neutral	2,29	neutral	-2,07	deleterious	-2,68	high_impact	3,82	neutral	0,77	damaging	0,15	deleterious	3,5	23,1	0,22	0,45	NA	NA	disease	0,84	disease	0,55	disease	0,69	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	-0,35	high_impact	2,15	0,55	0,8	59,12	10,27	P	0,61	P	0,9	polymorphism	0,99	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3379	3379	C	T	MI.10911	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	73	25	R	W	Cga/Tga	2,52	1	0	probably_damaging	1	neutral	0,11	neutral	1,6	deleterious	-9,89	deleterious	-7,14	high_impact	4,87	damaging	0,56	damaging	0,22	deleterious	5,01	25,1	0,06	0,35	NA	NA	disease	0,91	disease	0,73	disease	0,77	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	-0,23	high_impact	3,06	0,61	0,8	58,49	10,61	P	0,59	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3379	3379	C	G	MI.10912	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	73	25	R	G	Cga/Gga	2,52	1	0	probably_damaging	1	neutral	0,24	neutral	1,63	deleterious	-7,11	deleterious	-6,24	high_impact	4,87	neutral	0,7	neutral	0,43	deleterious	4,01	23,6	0,03	0,35	NA	NA	disease	0,84	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	-0,01	high_impact	3,06	0,14	0,8	58,49	10,61	P	0,66	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3380	3380	G	A	MI.10913	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	74	25	R	Q	cGa/cAa	2,75	1	0	probably_damaging	1	neutral	0,23	neutral	1,65	deleterious	-5,9	deleterious	-3,56	high_impact	4,87	neutral	0,62	neutral	0,31	deleterious	4,39	24,1	0,06	0,35	NA	NA	disease	0,85	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	-0,02	high_impact	3,06	0,69	0,85	58,49	10,61	P	0,65	P	1	polymorphism	1	0,43	.	.	.	.	.	.	COSM1599866	.	.	G3380A	MELAS	-	+	Reported	1
chrM	3380	3380	G	T	MI.10914	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	74	25	R	L	cGa/cTa	2,75	1	0	probably_damaging	1	neutral	1	neutral	1,63	deleterious	-7,04	deleterious	-6,25	high_impact	4,87	damaging	0,55	neutral	0,34	deleterious	4,16	23,8	0,03	0,35	NA	NA	disease	0,93	disease	0,7	disease	0,77	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,91	low_impact	-3,57	high_impact	1,96	high_impact	3,06	0,1	0,8	58,49	10,61	P	0,63	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3380	3380	G	C	MI.10915	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	74	25	R	P	cGa/cCa	2,75	1	0	probably_damaging	1	neutral	0,15	neutral	1,61	deleterious	-6,81	deleterious	-6,25	high_impact	4,87	damaging	0,56	damaging	0,28	deleterious	4,08	23,7	0,02	0,35	NA	NA	disease	0,9	disease	0,82	disease	0,82	6	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,92	low_impact	-3,57	medium_impact	-0,15	high_impact	3,06	0,11	0,8	58,49	10,61	P	0,68	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3382	3382	A	G	MI.10916	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	76	26	K	E	Aaa/Gaa	-0,7	0,1	0	probably_damaging	1	neutral	0,44	neutral	2,49	deleterious	-3,1	deleterious	-3,55	high_impact	4,12	neutral	0,8	damaging	0,2	deleterious	3,89	23,5	0,07	0,35	NA	NA	disease	0,87	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	0,22	high_impact	2,41	0,31	0,8	60,38	10,44	N	0,39	N	0,92	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3382	3382	A	C	MI.10917	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	76	26	K	Q	Aaa/Caa	-0,7	0,1	0	probably_damaging	1	neutral	0,21	neutral	2,45	deleterious	-3,55	deleterious	-3,55	high_impact	3,84	neutral	0,73	damaging	0,16	deleterious	3,34	22,9	0,13	0,4	NA	NA	disease	0,83	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	-0,05	high_impact	2,17	0,41	0,8	60,38	10,44	N	0,44	N	0,92	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3383	3383	A	C	MI.10918	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	77	26	K	T	aAa/aCa	8,49	1	0	probably_damaging	1	neutral	0,49	neutral	2,44	deleterious	-3,97	deleterious	-5,32	high_impact	4,46	neutral	0,69	damaging	0,14	deleterious	3,26	22,8	0,05	0,35	NA	NA	disease	0,83	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	0,27	high_impact	2,71	0,23	0,8	60,38	10,44	P	0,59	P	0,82	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3383	3383	A	T	MI.10919	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	77	26	K	M	aAa/aTa	8,49	1	0	probably_damaging	1	neutral	0,15	neutral	2,38	deleterious	-5,41	deleterious	-5,33	high_impact	4,81	neutral	0,75	damaging	0,15	deleterious	3,55	23,1	0,04	0,35	NA	NA	disease	0,88	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,15	high_impact	3,01	0,27	0,8	60,38	10,44	P	0,7	P	0,5	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9039	9039	G	T	MI.1092	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	513	171	M	I	atG/atT	5,68	1	0,01	probably_damaging	0,91	neutral	1	neutral	4,48	neutral	0,57	neutral	0,03	neutral_impact	-0,4	neutral	0,81	neutral	0,97	neutral	1,01	10,7	0,3	0,65	neutral	0,35	neutral	0,2	neutral	0,35	neutral	0,35	3	neutral	0,91	deleterious	0,55	neutral	-2	deleterious	0,6	low_impact	-1,71	high_impact	1,98	low_impact	-1,44	0,64	0,9	17,26	16,43	N	0,47	N	0,05	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3384	3384	A	T	MI.10920	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	78	26	K	N	aaA/aaT	8,49	1	0	probably_damaging	1	neutral	0,21	neutral	2,43	deleterious	-3,99	deleterious	-4,44	high_impact	4,46	neutral	0,74	damaging	0,15	deleterious	3,7	23,3	0,1	0,4	NA	NA	disease	0,84	disease	0,58	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	-0,05	high_impact	2,71	0,33	0,8	60,38	10,44	P	0,64	P	0,84	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3384	3384	A	C	MI.10921	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	78	26	K	N	aaA/aaC	8,49	1	0	probably_damaging	1	neutral	0,21	neutral	2,43	deleterious	-3,99	deleterious	-4,44	high_impact	4,46	neutral	0,74	damaging	0,15	deleterious	3,64	23,2	0,1	0,4	NA	NA	disease	0,84	disease	0,58	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	-0,05	high_impact	2,71	0,33	0,8	60,38	10,44	P	0,64	P	0,84	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3385	3385	A	G	MI.10922	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	79	27	I	V	Att/Gtt	1,83	0,91	0	benign	0,01	neutral	0,47	neutral	2,87	neutral	0,2	neutral	0,27	neutral_impact	0,13	neutral	0,75	neutral	0,96	deleterious	-0,02	2,43	0,52	0,6	NA	NA	neutral	0,09	neutral	0,12	neutral	0,24	5	neutral	0,52	deleterious	0,73	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,25	low_impact	-1,08	0,46	0,8	26,42	33,35	N	0,48	N	0,08	polymorphism	1	0,01	rs879050714	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3385	3385	A	C	MI.10923	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	79	27	I	L	Att/Ctt	1,83	0,91	0	benign	0,01	neutral	1	neutral	2,63	neutral	-0,81	neutral	-1,25	low_impact	0,82	neutral	0,84	neutral	0,77	deleterious	2,24	17,76	0,27	0,45	NA	NA	disease	0,6	neutral	0,17	neutral	0,44	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,19	medium_impact	1,12	high_impact	1,96	medium_impact	-0,47	0,57	0,8	26,42	33,35	N	0,25	N	0,13	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3385	3385	A	T	MI.10924	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	79	27	I	F	Att/Ttt	1,83	0,91	0	possibly_damaging	0,49	neutral	0,42	neutral	2,39	deleterious	-3,72	deleterious	-2,84	medium_impact	2,2	neutral	0,9	neutral	0,86	deleterious	3,32	22,9	0,08	0,35	NA	NA	disease	0,77	neutral	0,37	disease	0,63	3	neutral	0,56	neutral	0,47	NA	0	deleterious	0,61	medium_impact	-0,74	medium_impact	0,2	medium_impact	0,73	0,5	0,8	26,42	33,35	N	0,42	N	0,73	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3386	3386	T	G	MI.10925	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	80	27	I	S	aTt/aGt	-0,47	0,16	0	benign	0,36	neutral	0,34	neutral	2,37	deleterious	-4,44	deleterious	-4,09	medium_impact	3,12	neutral	0,69	neutral	0,47	deleterious	4,21	23,9	0,02	0,35	NA	NA	disease	0,83	disease	0,52	disease	0,76	5	neutral	0,6	deleterious	0,49	neutral	-3	deleterious	0,46	medium_impact	-0,52	medium_impact	0,11	medium_impact	1,54	0,25	0,8	26,42	33,35	N	0,42	N	0,84	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3386	3386	T	C	MI.10926	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	80	27	I	T	aTt/aCt	-0,47	0,16	0	benign	0,03	neutral	0,61	neutral	2,39	deleterious	-3,59	deleterious	-2,75	low_impact	1,9	neutral	0,82	neutral	0,95	deleterious	2,24	17,74	0,04	0,35	NA	NA	disease	0,63	neutral	0,27	neutral	0,46	1	neutral	0,35	deleterious	0,79	neutral	-6	neutral	0,19	medium_impact	0,67	medium_impact	0,38	medium_impact	0,47	0,19	0,8	26,42	33,35	N	0,29	N	0,77	polymorphism	1	0,12	.	.	.	.	.	MNGIE tissues	.	.	.	.	.	.	.	.	.
chrM	3386	3386	T	A	MI.10927	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	80	27	I	N	aTt/aAt	-0,47	0,16	0	possibly_damaging	0,68	neutral	0,25	neutral	2,36	deleterious	-5,47	deleterious	-4,99	high_impact	3,58	neutral	0,67	neutral	0,45	deleterious	4,49	24,3	0,04	0,35	NA	NA	disease	0,9	disease	0,51	disease	0,76	5	neutral	0,79	neutral	0,29	deleterious	1	deleterious	0,69	low_impact	-1,06	medium_impact	0,01	medium_impact	1,94	0,24	0,8	26,42	33,35	N	0,45	N	0,89	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3387	3387	T	A	MI.10928	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	81	27	I	M	atT/atA	3,67	0,46	0	possibly_damaging	0,68	neutral	0,16	neutral	2,4	deleterious	-3,4	neutral	-1,26	medium_impact	2,72	neutral	0,84	neutral	0,97	deleterious	2,5	19,49	0,17	0,45	NA	NA	disease	0,66	neutral	0,18	neutral	0,43	1	neutral	0,86	neutral	0,24	NA	0	deleterious	0,61	low_impact	-1,06	medium_impact	-0,13	medium_impact	1,19	0,56	0,8	26,42	33,35	N	0,49	N	0,6	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3387	3387	T	G	MI.10929	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	81	27	I	M	atT/atG	3,67	0,46	0	possibly_damaging	0,68	neutral	0,16	neutral	2,4	deleterious	-3,4	neutral	-1,26	medium_impact	2,72	neutral	0,84	neutral	0,97	deleterious	2,19	17,41	0,17	0,45	NA	NA	disease	0,66	neutral	0,18	neutral	0,43	1	neutral	0,86	neutral	0,24	NA	0	deleterious	0,61	low_impact	-1,06	medium_impact	-0,13	medium_impact	1,19	0,56	0,8	26,42	33,35	N	0,49	N	0,6	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9040	9040	C	G	MI.1093	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	514	172	H	D	Cac/Gac	-7,04	0	0	possibly_damaging	0,56	neutral	0,2	neutral	4,39	neutral	-0,27	deleterious	-5,43	medium_impact	2,32	neutral	0,8	neutral	0,35	deleterious	3,93	23,5	0,23	0,65	disease	0,6	disease	0,86	disease	0,69	disease	0,8	6	neutral	0,79	neutral	0,32	NA	0	deleterious	0,71	medium_impact	-0,86	medium_impact	-0,05	medium_impact	0,89	0,49	0,9	49,56	8,68	N	0,24	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3388	3388	C	G	MI.10930	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	82	28	L	V	Cta/Gta	-7,59	0	0	probably_damaging	1	neutral	0,4	neutral	2,6	neutral	-0,26	deleterious	-2,61	high_impact	4,36	damaging	0,6	neutral	0,47	deleterious	3,28	22,8	0,28	0,45	NA	NA	disease	0,73	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,18	high_impact	2,62	0,52	0,8	59,12	10,77	N	0,46	N	0,84	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3388	3388	C	A	MI.10931	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	82	28	L	M	Cta/Ata	-7,59	0	0	probably_damaging	1	neutral	0,12	neutral	2,56	neutral	-1,53	neutral	-1,75	medium_impact	2,77	neutral	0,6	neutral	0,61	deleterious	3,59	23,2	0,31	0,45	NA	NA	disease	0,61	neutral	0,3	neutral	0,44	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,81	low_impact	-3,57	medium_impact	-0,21	medium_impact	1,23	0,55	0,8	59,12	10,77	N	0,45	N	0,89	disease_causing_automatic	0	0,04	rs387906730	Pathogenic	Deafness,_nonsyndromic_sensorineural,_mitochondrial	RCV000022892.2	MedGen:OMIM	.	.	.	.	C3388A	Materally Inherited Nonsyndromic Deafness	.	.	Reported	1
chrM	3389	3389	T	A	MI.10932	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	83	28	L	Q	cTa/cAa	-2,08	0	0	probably_damaging	1	neutral	0,22	neutral	2,5	deleterious	-3,13	deleterious	-5,33	high_impact	4,71	neutral	0,65	neutral	0,43	deleterious	3,9	23,5	0,02	0,35	NA	NA	disease	0,85	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	-0,03	high_impact	2,93	0,14	0,8	59,12	10,77	P	0,63	P	0,99	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3389	3389	T	G	MI.10933	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	83	28	L	R	cTa/cGa	-2,08	0	0	probably_damaging	1	neutral	0,39	neutral	2,51	neutral	-1,97	deleterious	-5,34	high_impact	4,71	neutral	0,66	neutral	0,35	deleterious	4,06	23,7	0,01	0,35	NA	NA	disease	0,91	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,93	low_impact	-3,57	medium_impact	0,17	high_impact	2,93	0,1	0,8	59,12	10,77	P	0,62	P	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3389	3389	T	C	MI.10934	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	83	28	L	P	cTa/cCa	-2,08	0	0	probably_damaging	1	neutral	0,14	neutral	2,49	deleterious	-3,73	deleterious	-6,21	high_impact	4,71	neutral	0,65	neutral	0,43	deleterious	3,77	23,4	0,01	0,35	NA	NA	disease	0,87	disease	0,74	disease	0,77	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,93	low_impact	-3,57	medium_impact	-0,17	high_impact	2,93	0,09	0,8	59,12	10,77	P	0,64	P	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3391	3391	G	C	MI.10935	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	85	29	G	R	Ggc/Cgc	1,14	1	0,02	probably_damaging	1	neutral	0,46	neutral	2,44	deleterious	-4,91	deleterious	-6,83	high_impact	4,63	neutral	0,66	neutral	0,29	deleterious	3,75	23,3	0,01	0,35	NA	NA	disease	0,91	disease	0,75	disease	0,79	6	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,94	low_impact	-3,57	medium_impact	0,24	high_impact	2,86	0,58	0,8	60,06	10,35	P	0,62	P	0,99	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3391	3391	G	A	MI.10936	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	85	29	G	S	Ggc/Agc	1,14	1	0,02	probably_damaging	1	neutral	0,48	neutral	2,55	neutral	-1,84	deleterious	-4,92	low_impact	1,84	neutral	0,74	neutral	0,47	deleterious	2,97	22,1	0,03	0,35	NA	NA	disease	0,75	neutral	0,36	neutral	0,49	0	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,87	low_impact	-3,57	medium_impact	0,26	medium_impact	0,42	0,62	0,8	60,06	10,35	N	0,48	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3391	3391	G	T	MI.10937	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	85	29	G	C	Ggc/Tgc	1,14	1	0,02	probably_damaging	1	neutral	0,18	neutral	2,43	deleterious	-4,71	deleterious	-7,68	high_impact	4,63	neutral	0,68	neutral	0,29	deleterious	4	23,6	0,01	0,35	NA	NA	disease	0,91	disease	0,63	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	-0,09	high_impact	2,86	0,23	0,8	60,06	10,35	P	0,61	P	0,98	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3392	3392	G	C	MI.10938	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	86	29	G	A	gGc/gCc	5,96	1	0	probably_damaging	1	neutral	0,61	neutral	2,85	neutral	2,63	deleterious	-5,03	medium_impact	2,31	neutral	0,74	neutral	0,53	deleterious	2,97	22,1	0,07	0,35	NA	NA	disease	0,74	neutral	0,43	neutral	0,49	0	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,87	low_impact	-3,57	medium_impact	0,38	medium_impact	0,83	0,43	0,8	60,06	10,35	N	0,51	P	0,76	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3392	3392	G	A	MI.10939	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	86	29	G	D	gGc/gAc	5,96	1	0	probably_damaging	1	neutral	0,26	neutral	2,45	deleterious	-4,76	deleterious	-5,93	high_impact	4,63	neutral	0,7	neutral	0,36	deleterious	3,72	23,3	0,01	0,35	NA	NA	disease	0,92	disease	0,74	disease	0,8	6	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	0,02	high_impact	2,86	0,15	0,8	60,06	10,35	P	0,69	P	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9040	9040	C	A	MI.1094	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	514	172	H	N	Cac/Aac	-7,04	0	0	possibly_damaging	0,46	neutral	0,31	neutral	4,39	neutral	0,02	deleterious	-4,23	low_impact	1,49	neutral	0,78	neutral	0,4	deleterious	3,9	23,5	0,47	0,65	disease	0,59	disease	0,78	disease	0,54	disease	0,74	5	neutral	0,65	neutral	0,43	neutral	-3	deleterious	0,63	medium_impact	-0,69	medium_impact	0,1	medium_impact	0,18	0,43	0,9	49,56	8,68	N	0,23	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3392	3392	G	T	MI.10940	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	86	29	G	V	gGc/gTc	5,96	1	0	probably_damaging	1	neutral	0,59	neutral	2,46	deleterious	-3,93	deleterious	-7,72	high_impact	4,29	neutral	0,65	neutral	0,39	deleterious	3,63	23,2	0,01	0,35	NA	NA	disease	0,91	disease	0,65	disease	0,73	5	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,92	low_impact	-3,57	medium_impact	0,36	high_impact	2,56	0,17	0,8	60,06	10,35	P	0,63	P	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3394	3394	T	C	MI.10941	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	88	30	Y	H	Tat/Cat	-5,52	0	0,04	benign	0,11	neutral	0,55	neutral	2,7	neutral	-0,32	deleterious	-4,4	medium_impact	2,17	damaging	0,32	neutral	0,48	neutral	1,52	13,4	0,14	0,4	NA	NA	disease	0,83	disease	0,75	disease	0,64	3	neutral	0,36	deleterious	0,72	neutral	-3	neutral	0,34	medium_impact	0,1	medium_impact	0,32	medium_impact	0,71	0,11	0,8	55,35	9,53	P	0,76	P	0,22	disease_causing_automatic	0	0,14	rs41460449	Pathogenic	Leber's_optic_atrophy	RCV000010375.3	MedGen:OMIM:SNOMED_CT	acute leukemia platelets, leukocytes & bone marrow	.	.	0,89	T3394C	LHON/Diabetes/CPT deficiency/highaltitude adaptation	+	-	Reported/Unclear	26
chrM	3394	3394	T	G	MI.10942	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	88	30	Y	D	Tat/Gat	-5,52	0	0,04	probably_damaging	0,93	neutral	0,41	neutral	2,71	neutral	-0,42	deleterious	-8,85	medium_impact	3,46	neutral	0,7	neutral	0,41	deleterious	3,51	23,1	0,04	0,35	NA	NA	disease	0,92	disease	0,77	disease	0,8	6	neutral	0,93	neutral	0,24	deleterious	1	deleterious	0,85	low_impact	-1,81	medium_impact	0,19	medium_impact	1,83	0,08	0,8	55,35	9,53	N	0,45	N	0,93	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3394	3394	T	A	MI.10943	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	88	30	Y	N	Tat/Aat	-5,52	0	0,04	possibly_damaging	0,87	neutral	0,46	neutral	2,72	neutral	-0,65	deleterious	-7,96	high_impact	4,5	neutral	0,68	neutral	0,46	deleterious	2,22	17,63	0,08	0,35	NA	NA	disease	0,89	disease	0,74	disease	0,78	6	neutral	0,86	neutral	0,3	deleterious	1	deleterious	0,78	low_impact	-1,53	medium_impact	0,24	high_impact	2,74	0,11	0,8	55,35	9,53	P	0,56	P	0,85	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3395	3395	A	C	MI.10944	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	89	30	Y	S	tAt/tCt	3,67	1	0,01	possibly_damaging	0,81	neutral	0,65	neutral	2,81	neutral	0,17	deleterious	-7,95	medium_impact	2,27	neutral	0,61	neutral	0,55	deleterious	1,95	15,91	0,06	0,35	NA	NA	disease	0,88	disease	0,65	disease	0,52	0	neutral	0,78	neutral	0,42	NA	0	deleterious	0,82	low_impact	-1,34	medium_impact	0,43	medium_impact	0,79	0,16	0,8	55,35	9,53	N	0,48	N	0,85	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3395	3395	A	G	MI.10945	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	89	30	Y	C	tAt/tGt	3,67	1	0,01	benign	0,17	neutral	0,18	neutral	2,69	neutral	-2,68	deleterious	-7,95	high_impact	3,95	neutral	0,64	neutral	0,37	deleterious	3,34	22,9	0,04	0,35	NA	NA	disease	0,89	disease	0,76	disease	0,79	6	neutral	0,79	deleterious	0,51	neutral	-2	neutral	0,35	medium_impact	-0,1	medium_impact	-0,09	high_impact	2,26	0,04	0,8	55,35	9,53	P	0,62	P	0,92	polymorphism	1	0,37	.	.	.	.	.	.	.	CPD	0,74	A3395G	HCM with hearing loss	-	+	Reported	2
chrM	3395	3395	A	T	MI.10946	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	89	30	Y	F	tAt/tTt	3,67	1	0,01	possibly_damaging	0,77	neutral	0,7	neutral	2,73	neutral	0,77	deleterious	-3,53	medium_impact	2,63	neutral	0,62	neutral	0,42	neutral	1,64	14,09	0,2	0,45	NA	NA	disease	0,81	disease	0,69	disease	0,71	4	neutral	0,73	neutral	0,47	NA	0	deleterious	0,74	low_impact	-1,24	medium_impact	0,48	medium_impact	1,11	0,38	0,8	55,35	9,53	P	0,53	P	0,6	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3397	3397	A	T	MI.10947	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	91	31	M	L	Ata/Tta	-3,69	0	0,01	benign	0,23	neutral	0,46	neutral	2,81	neutral	-0,9	deleterious	-2,64	medium_impact	2,69	damaging	0,55	neutral	0,43	neutral	1,21	11,83	0,15	0,4	NA	NA	disease	0,82	disease	0,7	disease	0,73	5	neutral	0,44	deleterious	0,62	neutral	-3	neutral	0,36	medium_impact	-0,26	medium_impact	0,24	medium_impact	1,16	0,42	0,8	55,66	10,29	N	0,34	N	0,7	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3397	3397	A	G	MI.10948	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	91	31	M	V	Ata/Gta	-3,69	0	0,01	benign	0,32	neutral	0,41	neutral	2,85	neutral	-0,83	deleterious	-3,48	medium_impact	2,37	damaging	0,25	neutral	0,46	deleterious	0,63	8,38	0,15	0,4	NA	NA	disease	0,83	disease	0,62	disease	0,54	1	neutral	0,51	deleterious	0,55	neutral	-3	neutral	0,42	medium_impact	-0,44	medium_impact	0,19	medium_impact	0,88	0,41	0,8	55,66	10,29	P	0,94	P	0,84	disease_causing_automatic	0	0,12	rs199476120	Pathogenic|Pathogenic	Alzheimer's_disease|Parkinson_disease,_late-onset	RCV000010376.3|RCV000010377.2	MedGen:OMIM:SNOMED_CT|MedGen:OMIM:SNOMED_CT	.	.	.	.	A3397G	ADPD/PossiblyLVNC-cardiomyopathy associated	+	-	Reported	9
chrM	3397	3397	A	C	MI.10949	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	91	31	M	L	Ata/Cta	-3,69	0	0,01	benign	0,23	neutral	0,46	neutral	2,81	neutral	-0,9	deleterious	-2,64	medium_impact	2,69	damaging	0,55	neutral	0,43	neutral	1,18	11,65	0,15	0,4	NA	NA	disease	0,82	disease	0,7	disease	0,73	5	neutral	0,44	deleterious	0,62	neutral	-3	neutral	0,36	medium_impact	-0,26	medium_impact	0,24	medium_impact	1,16	0,42	0,8	55,66	10,29	N	0,34	N	0,7	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9040	9040	C	T	MI.1095	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	514	172	H	Y	Cac/Tac	-7,04	0	0	benign	0	neutral	1	neutral	4,4	neutral	0,28	deleterious	-3,71	low_impact	1,72	neutral	0,87	neutral	0,41	deleterious	3,71	23,3	0,52	0,65	disease	0,6	disease	0,8	neutral	0,46	disease	0,65	3	neutral	0	deleterious	1	neutral	-6	neutral	0,29	high_impact	2,09	high_impact	1,98	medium_impact	0,38	0,42	0,9	49,56	8,68	N	0,2	N	1	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3398	3398	T	C	MI.10950	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	92	31	M	T	aTa/aCa	8,49	1	0,02	benign	0,02	neutral	0,6	neutral	2,73	neutral	-2,58	deleterious	-5,28	medium_impact	2,33	damaging	0,25	neutral	0,6	deleterious	0,88	9,97	0,05	0,35	NA	NA	disease	0,87	disease	0,65	disease	0,66	3	neutral	0,37	deleterious	0,79	neutral	-3	neutral	0,32	medium_impact	0,84	medium_impact	0,37	medium_impact	0,85	0,14	0,8	55,66	10,29	P	0,93	P	0,41	polymorphism	1	0,15	rs201212638	.	.	.	.	.	.	CPD	1,34	T3398C	DMDF+HCM/GDM/possibly LVNC cardiomyopathy-associated	+	-	Reported	5
chrM	3398	3398	T	A	MI.10951	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	92	31	M	K	aTa/aAa	8,49	1	0,02	possibly_damaging	0,44	neutral	0,95	neutral	2,69	deleterious	-4	deleterious	-5,33	high_impact	4,26	neutral	0,67	neutral	0,39	deleterious	1,88	15,47	0,02	0,35	NA	NA	disease	0,93	disease	0,79	disease	0,83	7	neutral	0,38	deleterious	0,76	deleterious	1	deleterious	0,56	medium_impact	-0,65	medium_impact	0,99	high_impact	2,53	0,17	0,8	55,66	10,29	P	0,64	P	0,96	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3399	3399	A	C	MI.10952	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	93	31	M	I	atA/atC	5,73	1	0	benign	0,32	neutral	0,27	neutral	2,85	neutral	-0,41	deleterious	-3,5	low_impact	1,7	damaging	0,58	neutral	0,59	neutral	1,52	13,43	0,16	0,45	NA	NA	neutral	0,46	disease	0,52	neutral	0,33	3	neutral	0,68	deleterious	0,48	neutral	-6	neutral	0,4	medium_impact	-0,44	medium_impact	0,03	medium_impact	0,3	0,39	0,8	55,66	10,29	P	0,71	P	0,83	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3399	3399	A	T	MI.10953	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	93	31	M	I	atA/atT	5,73	1	0	benign	0,32	neutral	0,27	neutral	2,85	neutral	-0,41	deleterious	-3,5	low_impact	1,7	damaging	0,58	neutral	0,59	neutral	1,55	13,56	0,16	0,45	NA	NA	neutral	0,46	disease	0,52	neutral	0,33	3	neutral	0,68	deleterious	0,48	neutral	-6	neutral	0,4	medium_impact	-0,44	medium_impact	0,03	medium_impact	0,3	0,39	0,8	55,66	10,29	P	0,67	P	0,83	disease_causing	1	0,11	rs386828905	.	.	.	.	.	.	.	.	A3399T	Gestational Diabetes (GDM)	+	-	Reported	1
chrM	3400	3400	C	G	MI.10954	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	94	32	Q	E	Caa/Gaa	-0,93	0,02	0	probably_damaging	1	neutral	0,33	neutral	2,33	deleterious	-3,37	deleterious	-2,69	high_impact	4,48	neutral	0,66	damaging	0,06	deleterious	3,01	22,3	0,07	0,35	disease	0,56	disease	0,85	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	0,1	high_impact	2,72	0,39	0,8	59,12	10,34	N	0,48	N	0,93	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3400	3400	C	A	MI.10955	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	94	32	Q	K	Caa/Aaa	-0,93	0,02	0	probably_damaging	1	neutral	0,39	neutral	2,36	deleterious	-3,22	deleterious	-3,59	high_impact	4,83	neutral	0,63	damaging	0,04	deleterious	3,8	23,4	0,04	0,35	neutral	0,48	disease	0,92	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	0,17	high_impact	3,03	0,25	0,8	59,12	10,34	P	0,69	P	0,98	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3401	3401	A	G	MI.10956	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	95	32	Q	R	cAa/cGa	7,11	1	0	probably_damaging	1	neutral	0,4	neutral	2,32	deleterious	-3,6	deleterious	-3,59	high_impact	4,48	neutral	0,63	damaging	0,04	deleterious	3,25	22,8	0,04	0,35	disease	0,54	disease	0,9	disease	0,74	disease	0,78	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	0,18	high_impact	2,72	0,31	0,8	59,12	10,34	P	0,67	P	0,95	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3401	3401	A	T	MI.10957	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	95	32	Q	L	cAa/cTa	7,11	1	0	probably_damaging	1	neutral	0,7	neutral	2,27	deleterious	-4,79	deleterious	-6,3	high_impact	4,48	neutral	0,66	damaging	0,04	deleterious	3,53	23,1	0,02	0,35	disease	0,75	disease	0,91	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	0,48	high_impact	2,72	0,14	0,8	59,12	10,34	P	0,6	P	0,99	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3401	3401	A	C	MI.10958	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	95	32	Q	P	cAa/cCa	7,11	1	0	probably_damaging	1	neutral	0,21	neutral	2,25	deleterious	-5,6	deleterious	-5,39	high_impact	4,83	neutral	0,64	damaging	0,09	deleterious	3,15	22,6	0,02	0,35	disease	0,82	disease	0,92	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,94	low_impact	-3,57	medium_impact	-0,05	high_impact	3,03	0,2	0,8	59,12	10,34	P	0,79	P	0,98	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3402	3402	A	C	MI.10959	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	96	32	Q	H	caA/caC	8,49	1	0	probably_damaging	1	neutral	0,53	neutral	2,27	deleterious	-3,78	deleterious	-4,48	medium_impact	3,1	neutral	0,63	damaging	0,04	deleterious	3,26	22,8	0,04	0,35	neutral	0,48	disease	0,84	disease	0,67	disease	0,53	1	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,86	low_impact	-3,57	medium_impact	0,3	medium_impact	1,52	0,52	0,8	59,12	10,34	N	0,53	P	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9041	9041	A	T	MI.1096	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	515	172	H	L	cAc/cTc	5,68	1	0	benign	0,16	neutral	0,63	neutral	4,51	neutral	2,08	deleterious	-7,1	low_impact	1,28	neutral	0,82	neutral	0,36	deleterious	3,9	23,5	0,29	0,65	neutral	0,47	disease	0,88	disease	0,54	disease	0,79	6	neutral	0,25	deleterious	0,74	neutral	-6	deleterious	0,49	medium_impact	-0,07	medium_impact	0,42	medium_impact	0	0,36	0,9	49,56	8,68	N	0,42	N	0,96	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3402	3402	A	T	MI.10960	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	96	32	Q	H	caA/caT	8,49	1	0	probably_damaging	1	neutral	0,53	neutral	2,27	deleterious	-3,78	deleterious	-4,48	medium_impact	3,1	neutral	0,63	damaging	0,04	deleterious	3,41	23	0,04	0,35	neutral	0,48	disease	0,84	disease	0,67	disease	0,53	1	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,86	low_impact	-3,57	medium_impact	0,3	medium_impact	1,52	0,52	0,8	59,12	10,34	P	0,53	P	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3403	3403	C	G	MI.10961	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	97	33	L	V	Cta/Gta	1,6	0,83	0	possibly_damaging	0,74	neutral	0,64	neutral	2,78	neutral	-0,23	neutral	-2,17	medium_impact	2,32	neutral	0,83	neutral	0,54	deleterious	3,27	22,8	0,18	0,45	neutral	0,25	disease	0,65	neutral	0,3	neutral	0,48	0	neutral	0,7	neutral	0,45	NA	0	deleterious	0,57	low_impact	-1,18	medium_impact	0,42	medium_impact	0,84	0,43	0,8	53,46	9,37	N	0,26	N	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3403	3403	C	A	MI.10962	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	97	33	L	M	Cta/Ata	1,6	0,83	0	probably_damaging	0,97	neutral	0,22	neutral	2,75	neutral	-0,72	neutral	-1,32	medium_impact	2,48	neutral	0,84	neutral	0,61	deleterious	3,79	23,4	0,2	0,45	neutral	0,41	disease	0,54	neutral	0,25	neutral	0,48	0	neutral	0,98	neutral	0,13	deleterious	1	deleterious	0,71	low_impact	-2,17	medium_impact	-0,03	medium_impact	0,98	0,51	0,8	53,46	9,37	N	0,37	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3404	3404	T	A	MI.10963	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	98	33	L	Q	cTa/cAa	-0,47	0,13	0	probably_damaging	0,98	neutral	0,35	neutral	2,83	neutral	0,19	deleterious	-4,31	medium_impact	2,68	neutral	0,72	neutral	0,45	deleterious	4,15	23,8	0,04	0,35	neutral	0,22	disease	0,79	neutral	0,2	disease	0,62	2	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,74	low_impact	-2,34	medium_impact	0,12	medium_impact	1,15	0,1	0,8	53,46	9,37	N	0,43	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3404	3404	T	C	MI.10964	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	98	33	L	P	cTa/cCa	-0,47	0,13	0	probably_damaging	0,98	neutral	0,2	neutral	2,72	neutral	-2,02	deleterious	-5,23	high_impact	3,58	neutral	0,65	neutral	0,42	deleterious	3,87	23,5	0,03	0,35	neutral	0,48	disease	0,88	disease	0,57	disease	0,71	4	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-2,34	medium_impact	-0,06	medium_impact	1,94	0,12	0,8	53,46	9,37	N	0,44	N	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3404	3404	T	G	MI.10965	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	98	33	L	R	cTa/cGa	-0,47	0,13	0	probably_damaging	0,97	neutral	0,39	neutral	2,79	neutral	0,71	deleterious	-4,34	low_impact	1,87	neutral	0,67	neutral	0,4	deleterious	4,08	23,7	0,04	0,35	neutral	0,17	disease	0,85	neutral	0,38	disease	0,53	1	neutral	0,97	neutral	0,21	neutral	-2	deleterious	0,76	low_impact	-2,17	medium_impact	0,17	medium_impact	0,45	0,07	0,8	53,46	9,37	N	0,33	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3406	3406	C	G	MI.10966	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	100	34	R	G	Cgc/Ggc	-7,13	0	0	probably_damaging	1	neutral	0,4	neutral	1,63	deleterious	-7,38	deleterious	-6,31	high_impact	4,54	neutral	0,61	neutral	0,43	deleterious	4,09	23,7	0,02	0,35	disease	0,82	disease	0,85	disease	0,81	disease	0,8	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,18	high_impact	2,78	0,05	0,8	59,12	10,46	N	0,52	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3406	3406	C	T	MI.10967	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	100	34	R	C	Cgc/Tgc	-7,13	0	0	probably_damaging	1	neutral	0,17	neutral	1,6	deleterious	-9,35	deleterious	-7,21	high_impact	4,88	neutral	0,6	damaging	0,25	deleterious	4,89	24,9	0,04	0,35	disease	0,94	disease	0,92	disease	0,82	disease	0,83	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,94	low_impact	-3,57	medium_impact	-0,11	high_impact	3,07	0,41	0,8	59,12	10,46	P	0,57	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3406	3406	C	A	MI.10968	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	100	34	R	S	Cgc/Agc	-7,13	0	0	probably_damaging	1	neutral	0,39	neutral	1,64	deleterious	-6,53	deleterious	-5,4	high_impact	4,88	damaging	0,58	neutral	0,46	deleterious	4,44	24,2	0,02	0,35	disease	0,76	disease	0,92	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,92	low_impact	-3,57	medium_impact	0,17	high_impact	3,07	0,05	0,8	59,12	10,46	P	0,68	P	0,74	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3407	3407	G	C	MI.10969	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	101	34	R	P	cGc/cCc	5,5	1	0	probably_damaging	1	neutral	0,19	neutral	1,61	deleterious	-7,81	deleterious	-6,3	high_impact	4,88	neutral	0,69	neutral	0,32	deleterious	4,14	23,8	0,02	0,35	disease	0,87	disease	0,93	disease	0,81	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,94	low_impact	-3,57	medium_impact	-0,08	high_impact	3,07	0,04	0,8	59,12	10,46	P	0,74	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9041	9041	A	C	MI.1097	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	515	172	H	P	cAc/cCc	5,68	1	0	possibly_damaging	0,78	neutral	0,2	neutral	4,38	neutral	-0,85	deleterious	-6,34	medium_impact	2,87	neutral	0,73	damaging	0,27	deleterious	3,36	22,9	0,27	0,65	disease	0,75	disease	0,94	disease	0,72	disease	0,87	7	neutral	0,87	neutral	0,21	NA	0	deleterious	0,83	low_impact	-1,28	medium_impact	-0,05	medium_impact	1,36	0,41	0,9	49,56	8,68	N	0,51	P	1	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3407	3407	G	A	MI.10970	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	101	34	R	H	cGc/cAc	5,5	1	0	probably_damaging	1	neutral	0,52	neutral	1,62	deleterious	-7,08	deleterious	-4,5	high_impact	4,88	damaging	0,49	damaging	0,25	deleterious	4,35	24,1	0,05	0,35	disease	0,8	disease	0,89	disease	0,78	disease	0,81	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,92	low_impact	-3,57	medium_impact	0,29	high_impact	3,07	0,41	0,8	59,12	10,46	P	0,8	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	G3407A	HCM/Muscle involvement	+	-	Conflicting reports	3
chrM	3407	3407	G	T	MI.10971	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	101	34	R	L	cGc/cTc	5,5	1	0	probably_damaging	1	neutral	0,74	neutral	1,63	deleterious	-6,75	deleterious	-6,31	high_impact	4,88	damaging	0,59	neutral	0,35	deleterious	4,2	23,9	0,02	0,35	disease	0,8	disease	0,94	disease	0,78	disease	0,87	7	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,93	low_impact	-3,57	medium_impact	0,53	high_impact	3,07	0,02	0,8	59,12	10,46	P	0,76	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3409	3409	A	G	MI.10972	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	103	35	K	E	Aaa/Gaa	-1,85	0	0	probably_damaging	1	neutral	0,27	neutral	2,66	neutral	-1,53	deleterious	-3,61	high_impact	4,1	neutral	0,68	damaging	0,06	deleterious	3,92	23,5	0,11	0,4	neutral	0,34	disease	0,9	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,03	high_impact	2,39	0,44	0,8	59,43	10,53	N	0,42	N	0,92	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3409	3409	A	C	MI.10973	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	103	35	K	Q	Aaa/Caa	-1,85	0	0	probably_damaging	1	neutral	0,3	neutral	2,64	neutral	-0,7	deleterious	-3,61	high_impact	3,67	neutral	0,6	damaging	0,07	deleterious	3,37	22,9	0,27	0,45	neutral	0,39	disease	0,86	disease	0,55	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,07	high_impact	2,02	0,4	0,8	59,43	10,53	N	0,35	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3410	3410	A	C	MI.10974	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	104	35	K	T	aAa/aCa	8,49	1	0	probably_damaging	1	neutral	0,39	neutral	2,66	neutral	-0,67	deleterious	-5,41	high_impact	3,96	damaging	0,59	damaging	0,07	deleterious	3,54	23,1	0,06	0,35	neutral	0,3	disease	0,91	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	0,17	high_impact	2,27	0,15	0,8	59,43	10,53	P	0,59	P	0,82	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3410	3410	A	T	MI.10975	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	104	35	K	M	aAa/aTa	8,49	1	0	probably_damaging	1	neutral	0,22	neutral	2,62	neutral	-0,41	deleterious	-5,41	medium_impact	3,37	neutral	0,65	damaging	0,05	deleterious	3,87	23,5	0,06	0,35	neutral	0,37	disease	0,89	disease	0,56	disease	0,67	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,79	low_impact	-3,57	medium_impact	-0,03	medium_impact	1,76	0,15	0,8	59,43	10,53	P	0,58	P	0,5	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3411	3411	A	C	MI.10976	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	105	35	K	N	aaA/aaC	8,49	1	0	probably_damaging	1	neutral	0,31	neutral	2,63	neutral	-1,89	deleterious	-4,51	high_impact	4,3	neutral	0,63	damaging	0,06	deleterious	3,76	23,3	0,22	0,45	neutral	0,42	disease	0,88	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	0,08	high_impact	2,57	0,37	0,8	59,43	10,53	P	0,66	P	0,84	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3411	3411	A	T	MI.10977	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	105	35	K	N	aaA/aaT	8,49	1	0	probably_damaging	1	neutral	0,31	neutral	2,63	neutral	-1,89	deleterious	-4,51	high_impact	4,3	neutral	0,63	damaging	0,06	deleterious	3,89	23,5	0,22	0,45	neutral	0,42	disease	0,88	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	0,08	high_impact	2,57	0,37	0,8	59,43	10,53	P	0,66	P	0,84	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3412	3412	G	A	MI.10978	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	106	36	G	S	Ggc/Agc	-0,01	0,91	0	probably_damaging	1	neutral	0,4	neutral	1,12	deleterious	-5,95	deleterious	-5,42	high_impact	4,2	damaging	0,24	damaging	0,06	deleterious	4,16	23,8	0,02	0,35	disease	0,87	disease	0,92	disease	0,69	disease	0,78	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,92	low_impact	-3,57	medium_impact	0,18	high_impact	2,48	0,58	0,8	60,38	10,43	P	0,88	P	0,99	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3412	3412	G	T	MI.10979	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	106	36	G	C	Ggc/Tgc	-0,01	0,91	0	probably_damaging	1	neutral	0,17	neutral	1,08	deleterious	-8,53	deleterious	-8,13	high_impact	4,89	damaging	0,42	damaging	0,03	deleterious	4,02	23,6	0,02	0,35	disease	0,96	disease	0,95	disease	0,73	disease	0,81	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,94	low_impact	-3,57	medium_impact	-0,11	high_impact	3,08	0,2	0,8	60,38	10,43	P	0,59	P	0,98	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9041	9041	A	G	MI.1098	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	515	172	H	R	cAc/cGc	5,68	1	0	benign	0,38	neutral	0,34	neutral	4,4	neutral	0,18	deleterious	-4,55	medium_impact	2,52	neutral	0,83	neutral	0,33	deleterious	3,05	22,4	0,49	0,65	disease	0,57	disease	0,87	disease	0,58	disease	0,79	6	neutral	0,6	deleterious	0,48	neutral	-3	deleterious	0,66	medium_impact	-0,55	medium_impact	0,13	medium_impact	1,06	0,35	0,9	49,56	8,68	N	0,47	N	1	disease_causing	1	0,08	rs879244322	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3412	3412	G	C	MI.10980	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	106	36	G	R	Ggc/Cgc	-0,01	0,91	0	probably_damaging	1	neutral	0,37	neutral	1,09	deleterious	-8,09	deleterious	-7,22	high_impact	4,89	damaging	0,46	damaging	0,04	deleterious	3,85	23,4	0,01	0,35	disease	0,94	disease	0,95	disease	0,77	disease	0,85	7	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,95	low_impact	-3,57	medium_impact	0,15	high_impact	3,08	0,57	0,8	60,38	10,43	P	0,62	P	0,99	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3413	3413	G	C	MI.10981	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	107	36	G	A	gGc/gCc	8,95	1	0	probably_damaging	1	neutral	0,49	neutral	1,13	deleterious	-5,38	deleterious	-5,42	high_impact	4,09	damaging	0,3	damaging	0,07	deleterious	2,99	22,2	0,02	0,35	disease	0,84	disease	0,89	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	0,27	high_impact	2,38	0,3	0,8	60,38	10,43	P	0,75	P	0,76	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3413	3413	G	A	MI.10982	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	107	36	G	D	gGc/gAc	8,95	1	0	probably_damaging	1	neutral	0,2	neutral	1,1	deleterious	-8,01	deleterious	-6,32	high_impact	4,89	damaging	0,41	damaging	0,04	deleterious	3,81	23,4	0,01	0,35	disease	0,92	disease	0,95	disease	0,78	disease	0,86	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,92	low_impact	-3,57	medium_impact	-0,06	high_impact	3,08	0,17	0,8	60,38	10,43	P	0,79	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3413	3413	G	T	MI.10983	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	107	36	G	V	gGc/gTc	8,95	1	0	probably_damaging	1	neutral	0,49	neutral	1,09	deleterious	-7,26	deleterious	-8,13	high_impact	4,89	damaging	0,36	damaging	0,05	deleterious	3,66	23,2	0,01	0,35	disease	0,94	disease	0,96	disease	0,71	disease	0,82	6	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,94	low_impact	-3,57	medium_impact	0,27	high_impact	3,08	0,16	0,8	60,38	10,43	P	0,7	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3415	3415	C	G	MI.10984	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	109	37	P	A	Ccc/Gcc	-13,11	0	0	probably_damaging	1	neutral	0,52	neutral	1,22	deleterious	-5,75	deleterious	-7,16	high_impact	4,2	neutral	0,71	damaging	0,13	deleterious	2,92	21,9	0,06	0,35	neutral	0,42	disease	0,8	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	0,29	high_impact	2,48	0,68	0,85	59,43	10,72	N	0,3	N	0,78	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3415	3415	C	A	MI.10985	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	109	37	P	T	Ccc/Acc	-13,11	0	0	probably_damaging	1	neutral	0,41	neutral	1,19	deleterious	-6,45	deleterious	-7,16	high_impact	4,54	neutral	0,66	damaging	0,09	deleterious	3,55	23,1	0,04	0,35	disease	0,67	disease	0,87	disease	0,57	disease	0,7	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	0,19	high_impact	2,78	0,39	0,8	59,43	10,72	N	0,36	N	0,91	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3415	3415	C	T	MI.10986	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	109	37	P	S	Ccc/Tcc	-13,11	0	0	probably_damaging	1	neutral	0,42	neutral	1,21	deleterious	-6,02	deleterious	-7,16	high_impact	4,54	neutral	0,73	damaging	0,12	deleterious	3,81	23,4	0,04	0,35	disease	0,59	disease	0,86	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,2	high_impact	2,78	0,12	0,8	59,43	10,72	N	0,41	N	0,74	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3416	3416	C	T	MI.10987	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	110	37	P	L	cCc/cTc	7,11	1	0	probably_damaging	1	neutral	0,67	neutral	1,19	deleterious	-6,82	deleterious	-8,96	high_impact	4,54	neutral	0,78	damaging	0,1	deleterious	4,31	24	0,03	0,35	disease	0,82	disease	0,9	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	0,45	high_impact	2,78	0,55	0,8	59,43	10,72	P	0,56	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3416	3416	C	G	MI.10988	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	110	37	P	R	cCc/cGc	7,11	1	0	probably_damaging	1	neutral	0,39	neutral	1,18	deleterious	-6,98	deleterious	-8,06	high_impact	4,54	neutral	0,74	damaging	0,1	deleterious	3,5	23,1	0,02	0,35	disease	0,84	disease	0,91	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	0,17	high_impact	2,78	0,17	0,8	59,43	10,72	P	0,62	P	0,71	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3416	3416	C	A	MI.10989	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	110	37	P	H	cCc/cAc	7,11	1	0	probably_damaging	1	neutral	0,53	neutral	1,17	deleterious	-8,08	deleterious	-8,06	high_impact	4,54	neutral	0,69	damaging	0,1	deleterious	3,94	23,5	0,03	0,35	disease	0,91	disease	0,89	disease	0,71	disease	0,81	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,3	high_impact	2,78	0,19	0,8	59,43	10,72	P	0,61	P	0,69	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9042	9042	C	G	MI.1099	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	516	172	H	Q	caC/caG	7,07	1	0	possibly_damaging	0,6	neutral	0,52	neutral	4,42	neutral	0,93	deleterious	-3,47	neutral_impact	-0,36	neutral	0,68	neutral	0,6	neutral	0,96	10,45	0,49	0,65	neutral	0,44	neutral	0,21	neutral	0,36	neutral	0,36	3	neutral	0,57	neutral	0,46	neutral	-3	deleterious	0,55	medium_impact	-0,92	medium_impact	0,31	low_impact	-1,41	0,44	0,9	49,56	8,68	P	0,5	N	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3418	3418	A	G	MI.10990	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	112	38	N	D	Aac/Gac	-4,15	0	0	probably_damaging	1	neutral	0,32	neutral	2,63	neutral	-1,27	deleterious	-4,47	medium_impact	3,49	neutral	0,72	damaging	0,11	deleterious	3,75	23,3	0,32	0,5	neutral	0,23	disease	0,8	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,77	low_impact	-3,57	medium_impact	0,09	medium_impact	1,86	0,19	0,8	59,75	10,53	N	0,4	N	0,97	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	A3418G	AMegL	+	-	Reported	1
chrM	3418	3418	A	C	MI.10991	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	112	38	N	H	Aac/Cac	-4,15	0	0	probably_damaging	1	neutral	0,55	neutral	2,51	deleterious	-3,4	deleterious	-4,47	high_impact	4,81	neutral	0,68	damaging	0,08	deleterious	2,91	21,9	0,17	0,45	neutral	0,33	disease	0,83	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,32	high_impact	3,01	0,19	0,8	59,75	10,53	P	0,58	P	0,97	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3418	3418	A	T	MI.10992	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	112	38	N	Y	Aac/Tac	-4,15	0	0	probably_damaging	1	neutral	1	neutral	2,5	deleterious	-4,31	deleterious	-7,16	high_impact	3,71	neutral	0,7	damaging	0,07	deleterious	3,65	23,2	0,06	0,35	disease	0,52	disease	0,9	disease	0,69	disease	0,74	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,85	low_impact	-3,57	high_impact	1,96	high_impact	2,05	0,16	0,8	59,75	10,53	N	0,27	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3419	3419	A	T	MI.10993	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	113	38	N	I	aAc/aTc	8,49	1	0	probably_damaging	1	neutral	0,45	neutral	2,5	deleterious	-3,99	deleterious	-8,05	high_impact	4,81	neutral	0,75	damaging	0,14	deleterious	3,89	23,5	0,06	0,35	neutral	0,45	disease	0,89	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,23	high_impact	3,01	0,1	0,8	59,75	10,53	P	0,72	P	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3419	3419	A	G	MI.10994	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	113	38	N	S	aAc/aGc	8,49	1	0	probably_damaging	1	neutral	0,53	neutral	2,57	neutral	-1,96	deleterious	-4,46	high_impact	3,71	neutral	0,66	damaging	0,11	deleterious	3,04	22,4	0,34	0,5	neutral	0,2	disease	0,8	disease	0,57	disease	0,62	2	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,3	high_impact	2,05	0,18	0,8	59,75	10,53	P	0,56	P	0,9	polymorphism	0,99	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3419	3419	A	C	MI.10995	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	113	38	N	T	aAc/aCc	8,49	1	0	probably_damaging	1	neutral	0,49	neutral	2,57	neutral	-2,05	deleterious	-5,36	medium_impact	3,34	neutral	0,64	damaging	0,1	deleterious	3,34	22,9	0,17	0,45	neutral	0,2	disease	0,87	disease	0,58	disease	0,69	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,8	low_impact	-3,57	medium_impact	0,27	medium_impact	1,73	0,2	0,8	59,75	10,53	P	0,53	P	0,96	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3420	3420	C	A	MI.10996	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	114	38	N	K	aaC/aaA	8,49	1	0	probably_damaging	1	neutral	0,5	neutral	2,59	neutral	-1,69	deleterious	-5,37	high_impact	4	neutral	0,75	damaging	0,1	deleterious	4,37	24,1	0,2	0,45	neutral	0,18	disease	0,87	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,28	high_impact	2,31	0,27	0,8	59,75	10,53	P	0,59	P	1	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3420	3420	C	G	MI.10997	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	114	38	N	K	aaC/aaG	8,49	1	0	probably_damaging	1	neutral	0,5	neutral	2,59	neutral	-1,69	deleterious	-5,37	high_impact	4	neutral	0,75	damaging	0,1	deleterious	3,85	23,4	0,2	0,45	neutral	0,18	disease	0,87	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,28	high_impact	2,31	0,27	0,8	59,75	10,53	P	0,59	P	1	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3421	3421	G	A	MI.10998	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	115	39	V	I	Gtt/Att	-2,31	0	0,02	benign	0	neutral	0,49	neutral	2,76	neutral	-0,81	neutral	0,19	neutral_impact	-0,71	neutral	0,74	neutral	0,91	neutral	-1,07	0,01	0,37	0,5	neutral	0,17	neutral	0,05	neutral	0,14	neutral	0,22	6	neutral	0,51	deleterious	0,75	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,27	low_impact	-1,81	0,74	0,85	52,52	8,44	N	0,48	N	0	polymorphism	1	0,01	.	.	.	.	.	pancreatic cancer cell line	COSM1155613	CPD	53,41	G3421A	MIDD	+	-	Reported	1
chrM	3421	3421	G	C	MI.10999	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	115	39	V	L	Gtt/Ctt	-2,31	0	0,02	benign	0,02	neutral	0,8	neutral	2,74	neutral	-0,97	neutral	-1,46	neutral_impact	0,77	neutral	0,75	neutral	0,61	neutral	1,46	13,1	0,27	0,45	neutral	0,19	disease	0,51	neutral	0,25	neutral	0,44	1	neutral	0,15	deleterious	0,89	neutral	-6	neutral	0,15	medium_impact	0,84	medium_impact	0,61	medium_impact	-0,52	0,46	0,8	52,52	8,44	N	0,3	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8531	8531	A	G	MI.11	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	5	2	N	S	aAc/aGc	6,84	1	0	probably_damaging	0,95	neutral	0,13	neutral	4,68	neutral	-0,02	deleterious	-2,52	low_impact	1,9	neutral	0,91	neutral	0,62	deleterious	3,55	23,1	0,78	0,8	neutral	0,41	neutral	0,26	neutral	0,1	neutral	0,45	1	neutral	0,98	neutral	0,09	neutral	-2	deleterious	0,64	low_impact	-1,97	medium_impact	-0,18	medium_impact	0,53	0,16	0,9	41,59	7,23	P	0,64	P	0,82	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8576	8576	T	A	MI.110	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	50	17	L	Q	cTa/cAa	-0,57	0	0	probably_damaging	1	deleterious	0,02	neutral	4,41	deleterious	-4,16	deleterious	-4,16	medium_impact	2,42	neutral	0,87	neutral	0,71	deleterious	2,76	21,1	0,19	0,65	disease	0,89	disease	0,71	disease	0,62	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,82	low_impact	-3,6	medium_impact	-0,66	medium_impact	0,98	0,73	0,9	28,76	21,22	N	0,37	N	0,36	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9042	9042	C	A	MI.1100	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	516	172	H	Q	caC/caA	7,07	1	0	possibly_damaging	0,6	neutral	0,52	neutral	4,42	neutral	0,93	deleterious	-3,47	neutral_impact	-0,36	neutral	0,68	neutral	0,6	neutral	1,3	12,28	0,49	0,65	neutral	0,44	neutral	0,21	neutral	0,36	neutral	0,36	3	neutral	0,57	neutral	0,46	neutral	-3	deleterious	0,55	medium_impact	-0,92	medium_impact	0,31	low_impact	-1,41	0,44	0,9	49,56	8,68	P	0,5	N	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3421	3421	G	T	MI.11000	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	115	39	V	F	Gtt/Ttt	-2,31	0	0,02	benign	0,23	neutral	0,7	neutral	2,67	neutral	-2,16	deleterious	-3,24	low_impact	1,84	neutral	0,72	neutral	0,48	deleterious	1,85	15,27	0,06	0,35	neutral	0,35	disease	0,78	disease	0,55	disease	0,72	4	neutral	0,19	deleterious	0,74	neutral	-6	neutral	0,37	medium_impact	-0,26	medium_impact	0,48	medium_impact	0,42	0,28	0,8	52,52	8,44	N	0,26	N	0,56	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3422	3422	T	C	MI.11001	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	116	39	V	A	gTt/gCt	-0,24	0	0	benign	0,1	neutral	0,79	neutral	2,71	neutral	-1,03	deleterious	-3,4	low_impact	1,53	neutral	0,77	neutral	0,63	neutral	1,52	13,44	0,21	0,45	neutral	0,16	disease	0,54	neutral	0,43	neutral	0,49	0	neutral	0,1	deleterious	0,85	neutral	-6	neutral	0,19	medium_impact	0,15	medium_impact	0,6	medium_impact	0,15	0,26	0,8	52,52	8,44	N	0,23	N	0,69	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3422	3422	T	G	MI.11002	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	116	39	V	G	gTt/gGt	-0,24	0	0	benign	0,29	neutral	0,5	neutral	2,64	neutral	-2,58	deleterious	-6,06	medium_impact	2,82	neutral	0,69	neutral	0,45	deleterious	1,9	15,58	0,06	0,35	neutral	0,37	disease	0,62	disease	0,55	disease	0,68	4	neutral	0,4	deleterious	0,61	neutral	-3	neutral	0,29	medium_impact	-0,39	medium_impact	0,28	medium_impact	1,27	0,12	0,8	52,52	8,44	N	0,31	N	0,91	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3422	3422	T	A	MI.11003	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	116	39	V	D	gTt/gAt	-0,24	0	0	benign	0,36	neutral	0,44	neutral	2,64	neutral	-2,18	deleterious	-5,52	medium_impact	2,82	neutral	0,73	neutral	0,41	deleterious	2,56	19,87	0,04	0,35	neutral	0,35	disease	0,82	disease	0,6	disease	0,74	5	neutral	0,49	deleterious	0,54	neutral	-3	deleterious	0,43	medium_impact	-0,52	medium_impact	0,22	medium_impact	1,27	0,05	0,8	52,52	8,44	N	0,29	N	0,92	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3424	3424	G	C	MI.11004	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	118	40	V	L	Gta/Cta	-8,05	0	0	possibly_damaging	0,52	neutral	0,26	neutral	2,42	neutral	-2,23	neutral	-2,46	medium_impact	3	neutral	0,76	damaging	0,06	deleterious	3,4	23	0,15	0,4	neutral	0,21	disease	0,69	disease	0,6	neutral	0,48	0	neutral	0,72	neutral	0,37	NA	0	deleterious	0,47	medium_impact	-0,78	medium_impact	0,02	medium_impact	1,43	0,48	0,8	57,86	8,72	N	0,32	N	0,7	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3424	3424	G	T	MI.11005	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	118	40	V	L	Gta/Tta	-8,05	0	0	possibly_damaging	0,52	neutral	0,26	neutral	2,42	neutral	-2,23	neutral	-2,46	medium_impact	3	neutral	0,76	damaging	0,06	deleterious	3,56	23,1	0,15	0,4	neutral	0,21	disease	0,69	disease	0,6	neutral	0,48	0	neutral	0,72	neutral	0,37	NA	0	deleterious	0,47	medium_impact	-0,78	medium_impact	0,02	medium_impact	1,43	0,48	0,8	57,86	8,72	N	0,32	N	0,7	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3424	3424	G	A	MI.11006	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	118	40	V	M	Gta/Ata	-8,05	0	0	probably_damaging	0,96	neutral	0,11	neutral	2,33	deleterious	-3,82	deleterious	-2,57	high_impact	3,64	neutral	0,79	damaging	0,11	deleterious	3,59	23,2	0,1	0,4	neutral	0,39	disease	0,76	disease	0,73	disease	0,7	4	deleterious	0,98	neutral	0,08	deleterious	2	deleterious	0,74	low_impact	-2,05	medium_impact	-0,23	medium_impact	1,99	0,57	0,8	57,86	8,72	N	0,35	N	0,75	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3425	3425	T	C	MI.11007	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	119	40	V	A	gTa/gCa	4,13	1	0	possibly_damaging	0,74	neutral	0,67	neutral	2,44	neutral	-1,93	deleterious	-3,55	medium_impact	3,08	neutral	0,75	damaging	0,12	deleterious	3,42	23	0,09	0,35	neutral	0,22	disease	0,72	disease	0,71	disease	0,7	4	neutral	0,69	neutral	0,47	NA	0	deleterious	0,67	low_impact	-1,18	medium_impact	0,45	medium_impact	1,5	0,17	0,8	57,86	8,72	N	0,52	P	0,89	polymorphism	1	0,12	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	3425	3425	T	A	MI.11008	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	119	40	V	E	gTa/gAa	4,13	1	0	probably_damaging	0,98	neutral	0,88	neutral	2,33	deleterious	-4,06	deleterious	-5,36	high_impact	4,75	neutral	0,81	damaging	0,12	deleterious	4,5	24,3	0,02	0,35	neutral	0,44	disease	0,87	disease	0,81	disease	0,81	6	neutral	0,98	neutral	0,45	deleterious	2	deleterious	0,83	low_impact	-2,34	medium_impact	0,76	high_impact	2,96	0,08	0,8	57,86	8,72	P	0,71	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3425	3425	T	G	MI.11009	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	119	40	V	G	gTa/gGa	4,13	1	0	probably_damaging	0,97	neutral	0,5	neutral	2,32	deleterious	-4,24	deleterious	-6,24	high_impact	4,05	neutral	0,78	damaging	0,1	deleterious	3,73	23,3	0,03	0,35	disease	0,53	disease	0,76	disease	0,73	disease	0,73	5	neutral	0,97	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-2,17	medium_impact	0,28	high_impact	2,35	0,14	0,8	57,86	8,72	N	0,52	P	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9043	9043	C	A	MI.1101	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	517	173	L	M	Cta/Ata	-1,26	0	0	probably_damaging	1	deleterious	0,04	neutral	3,7	neutral	-2,43	neutral	-1,79	medium_impact	3	neutral	0,73	damaging	0,18	deleterious	3,9	23,5	0,24	0,65	disease	0,79	disease	0,53	neutral	0,4	disease	0,57	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,75	low_impact	-3,6	medium_impact	-0,49	medium_impact	1,47	0,57	0,9	48,67	8,82	N	0,36	N	0,96	disease_causing	0,97	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3427	3427	G	T	MI.11010	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	121	41	G	C	Ggc/Tgc	-7,13	0	0	probably_damaging	1	neutral	0,18	neutral	2,12	deleterious	-5,53	deleterious	-8,02	high_impact	4,8	damaging	0,48	damaging	0,01	deleterious	3,99	23,6	0,05	0,35	disease	0,51	disease	0,94	disease	0,75	disease	0,87	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	-0,09	high_impact	3	0,16	0,8	59,75	10,46	P	0,55	P	0,98	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3427	3427	G	C	MI.11011	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	121	41	G	R	Ggc/Cgc	-7,13	0	0	probably_damaging	1	neutral	0,52	neutral	2,14	deleterious	-4,67	deleterious	-7,12	high_impact	4,46	damaging	0,49	damaging	0,01	deleterious	3,8	23,4	0,05	0,35	disease	0,77	disease	0,93	disease	0,83	disease	0,87	7	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,93	low_impact	-3,57	medium_impact	0,29	high_impact	2,71	0,59	0,8	59,75	10,46	N	0,51	P	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3427	3427	G	A	MI.11012	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	121	41	G	S	Ggc/Agc	-7,13	0	0	probably_damaging	1	neutral	0,5	neutral	2,26	neutral	-2,5	deleterious	-5,33	medium_impact	2,82	damaging	0,44	damaging	0,05	deleterious	4,07	23,7	0,08	0,35	neutral	0,44	disease	0,9	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,87	low_impact	-3,57	medium_impact	0,28	medium_impact	1,27	0,49	0,8	59,75	10,46	N	0,39	N	0,99	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3428	3428	G	A	MI.11013	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	122	41	G	D	gGc/gAc	8,95	1	0	probably_damaging	1	neutral	0,27	neutral	2,15	deleterious	-4,24	deleterious	-6,24	high_impact	4,46	damaging	0,47	damaging	0,01	deleterious	3,81	23,4	0,05	0,35	disease	0,79	disease	0,93	disease	0,83	disease	0,87	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	0,03	high_impact	2,71	0,18	0,8	59,75	10,46	P	0,73	P	1	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3428	3428	G	C	MI.11014	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	122	41	G	A	gGc/gCc	8,95	1	0	probably_damaging	1	neutral	0,58	neutral	2,25	neutral	-2,58	deleterious	-5,31	high_impact	3,76	damaging	0,48	damaging	0,07	deleterious	3,01	22,3	0,09	0,35	neutral	0,39	disease	0,86	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,35	high_impact	2,1	0,41	0,8	59,75	10,46	P	0,6	P	0,76	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3428	3428	G	T	MI.11015	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	122	41	G	V	gGc/gTc	8,95	1	0	probably_damaging	1	neutral	0,57	neutral	2,15	deleterious	-4,19	deleterious	-8,01	high_impact	4	damaging	0,43	damaging	0,02	deleterious	3,65	23,2	0,05	0,35	disease	0,63	disease	0,94	disease	0,74	disease	0,86	7	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,34	high_impact	2,31	0,2	0,8	59,75	10,46	P	0,67	P	1	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3430	3430	C	T	MI.11016	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	124	42	P	S	Ccc/Tcc	-20	0	0	probably_damaging	1	neutral	0,4	neutral	2,73	neutral	-2,77	deleterious	-7,1	medium_impact	3,5	neutral	0,72	damaging	0,12	deleterious	3,82	23,4	0,22	0,45	neutral	0,19	disease	0,8	neutral	0,45	disease	0,62	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,18	medium_impact	1,87	0,12	0,8	60,06	10,23	N	0,32	N	0,74	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3430	3430	C	A	MI.11017	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	124	42	P	T	Ccc/Acc	-20	0	0	probably_damaging	1	neutral	0,39	neutral	2,73	neutral	-2,88	deleterious	-7,11	high_impact	3,75	neutral	0,75	damaging	0,12	deleterious	3,56	23,1	0,11	0,4	neutral	0,21	disease	0,78	neutral	0,45	disease	0,61	2	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	0,17	high_impact	2,09	0,54	0,8	60,06	10,23	N	0,31	N	0,91	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3430	3430	C	G	MI.11018	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	124	42	P	A	Ccc/Gcc	-20	0	0	probably_damaging	1	neutral	0,51	neutral	2,77	neutral	-2,31	deleterious	-7,11	high_impact	3,61	neutral	0,76	damaging	0,15	deleterious	2,91	21,9	0,16	0,45	neutral	0,18	disease	0,69	neutral	0,46	neutral	0,49	0	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,74	low_impact	-3,57	medium_impact	0,29	medium_impact	1,96	0,62	0,8	60,06	10,23	N	0,29	N	0,78	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3431	3431	C	G	MI.11019	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	125	42	P	R	cCc/cGc	3,44	0,99	0	probably_damaging	1	neutral	0,35	neutral	2,69	neutral	-2,94	deleterious	-8,01	medium_impact	3,4	neutral	0,78	damaging	0,1	deleterious	3,54	23,1	0,04	0,35	neutral	0,25	disease	0,87	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,79	low_impact	-3,57	medium_impact	0,12	medium_impact	1,78	0,32	0,8	60,06	10,23	N	0,4	N	0,71	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9043	9043	C	G	MI.1102	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	517	173	L	V	Cta/Gta	-1,26	0	0	probably_damaging	0,99	deleterious	0,03	neutral	3,67	neutral	-2,62	deleterious	-2,68	medium_impact	2,4	damaging	0,47	damaging	0,14	deleterious	3,46	23	0,22	0,65	neutral	0,41	disease	0,6	disease	0,61	disease	0,58	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,72	low_impact	-2,65	medium_impact	-0,56	medium_impact	0,96	0,64	0,9	48,67	8,82	N	0,31	N	0,87	disease_causing	0,97	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3431	3431	C	A	MI.11020	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	125	42	P	H	cCc/cAc	3,44	0,99	0	probably_damaging	1	neutral	0,54	neutral	2,67	deleterious	-4,32	deleterious	-8,01	high_impact	4,3	neutral	0,71	damaging	0,1	deleterious	3,97	23,6	0,07	0,35	neutral	0,4	disease	0,83	disease	0,59	disease	0,67	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,31	high_impact	2,57	0,3	0,8	60,06	10,23	N	0,47	N	0,69	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3431	3431	C	T	MI.11021	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	125	42	P	L	cCc/cTc	3,44	0,99	0	probably_damaging	1	neutral	0,66	neutral	2,8	neutral	-2,41	deleterious	-8,9	medium_impact	2,1	neutral	0,7	damaging	0,08	deleterious	4,34	24	0,13	0,4	neutral	0,12	disease	0,79	neutral	0,32	neutral	0,49	0	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	0,44	medium_impact	0,65	0,71	0,85	60,06	10,23	N	0,34	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3433	3433	T	G	MI.11022	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	127	43	Y	D	Tac/Gac	-11,73	0	0	benign	0,01	neutral	0,2	neutral	2,74	neutral	-1,79	deleterious	-7,07	medium_impact	3,27	neutral	0,79	neutral	0,4	deleterious	3,61	23,2	0,05	0,35	neutral	0,43	disease	0,81	disease	0,73	disease	0,76	5	neutral	0,8	deleterious	0,6	neutral	-3	neutral	0,25	medium_impact	1,12	medium_impact	-0,06	medium_impact	1,67	0,15	0,8	23,9	10,39	N	0,4	N	0,99	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3433	3433	T	C	MI.11023	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	127	43	Y	H	Tac/Cac	-11,73	0	0	benign	0,01	neutral	0,53	neutral	2,75	neutral	-0,78	deleterious	-3,48	low_impact	1,43	neutral	0,87	neutral	0,88	deleterious	2,16	17,22	0,15	0,4	neutral	0,23	disease	0,63	neutral	0,4	neutral	0,47	1	neutral	0,45	deleterious	0,76	neutral	-6	neutral	0,19	medium_impact	1,12	medium_impact	0,3	medium_impact	0,06	0,19	0,8	23,9	10,39	N	0,34	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3433	3433	T	A	MI.11024	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	127	43	Y	N	Tac/Aac	-11,73	0	0	benign	0,01	neutral	0,34	neutral	2,76	neutral	-1,32	deleterious	-6,27	medium_impact	2,17	neutral	0,81	neutral	0,65	deleterious	3,62	23,2	0,08	0,35	neutral	0,33	disease	0,76	disease	0,55	disease	0,65	3	neutral	0,65	deleterious	0,67	neutral	-3	neutral	0,22	medium_impact	1,12	medium_impact	0,11	medium_impact	0,71	0,14	0,8	23,9	10,39	N	0,36	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3434	3434	A	C	MI.11025	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	128	43	Y	S	tAc/tCc	0,68	0	0,01	benign	0,18	neutral	0,4	neutral	2,81	neutral	-0,43	deleterious	-6,08	low_impact	1,54	neutral	0,74	neutral	0,52	deleterious	1,87	15,39	0,08	0,35	neutral	0,17	disease	0,73	disease	0,55	disease	0,63	3	neutral	0,52	deleterious	0,61	neutral	-6	neutral	0,26	medium_impact	-0,13	medium_impact	0,18	medium_impact	0,16	0,18	0,8	23,9	10,39	N	0,3	N	0,93	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3434	3434	A	T	MI.11026	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	128	43	Y	F	tAc/tTc	0,68	0	0,01	benign	0,01	neutral	0,7	neutral	2,81	neutral	1,34	neutral	-2,32	neutral_impact	-0,44	neutral	0,87	neutral	0,9	deleterious	0,44	6,93	0,26	0,45	neutral	0,11	neutral	0,37	neutral	0,26	neutral	0,43	1	neutral	0,28	deleterious	0,85	neutral	-6	neutral	0,15	medium_impact	1,12	medium_impact	0,48	low_impact	-1,57	0,33	0,8	23,9	10,39	N	0,34	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3434	3434	A	G	MI.11027	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	128	43	Y	C	tAc/tGc	0,68	0	0,01	benign	0,02	neutral	0,17	neutral	2,74	neutral	-2,26	deleterious	-6,16	low_impact	1,89	neutral	0,85	neutral	0,8	neutral	1,51	13,39	0,04	0,35	neutral	0,37	disease	0,81	neutral	0,37	disease	0,54	1	neutral	0,82	deleterious	0,58	neutral	-6	neutral	0,22	medium_impact	0,84	medium_impact	-0,11	medium_impact	0,46	0,11	0,8	23,9	10,39	N	0,38	N	0,6	polymorphism	1	0,1	rs202123618	.	.	.	.	prostate tumor	.	.	.	.	.	.	.	.	.
chrM	3436	3436	G	T	MI.11028	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	130	44	G	W	Ggg/Tgg	-5,3	0	0	probably_damaging	1	neutral	0,18	neutral	1,07	deleterious	-9,79	deleterious	-7,23	high_impact	4,58	neutral	0,68	damaging	0,06	deleterious	4,34	24	0,02	0,35	disease	0,96	disease	0,92	disease	0,8	disease	0,84	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,92	low_impact	-3,57	medium_impact	-0,09	high_impact	2,81	0,11	0,8	58,81	10,54	N	0,44	N	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3436	3436	G	C	MI.11029	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	130	44	G	R	Ggg/Cgg	-5,3	0	0	probably_damaging	1	neutral	0,35	neutral	1,09	deleterious	-7,33	deleterious	-7,23	high_impact	4,93	neutral	0,71	damaging	0,06	deleterious	3,88	23,5	0,02	0,35	disease	0,54	disease	0,94	disease	0,84	disease	0,91	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	0,12	high_impact	3,12	0,52	0,8	58,81	10,54	P	0,6	P	0,99	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9044	9044	T	C	MI.1103	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	518	173	L	P	cTa/cCa	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	3,48	deleterious	-7,72	deleterious	-6,29	high_impact	4,35	damaging	0,35	damaging	0,14	deleterious	3,98	23,6	0,12	0,65	disease	0,63	disease	0,82	disease	0,73	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,6	low_impact	-1,4	high_impact	2,63	0,7	0,9	48,67	8,82	P	0,54	P	1	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3437	3437	G	T	MI.11030	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	131	44	G	V	gGg/gTg	7,11	1	0	probably_damaging	1	neutral	0,51	neutral	1,09	deleterious	-7,12	deleterious	-8,13	high_impact	4,93	damaging	0,55	damaging	0,06	deleterious	3,7	23,3	0,02	0,35	disease	0,75	disease	0,94	disease	0,75	disease	0,87	7	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	0,29	high_impact	3,12	0,15	0,8	58,81	10,54	P	0,65	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3437	3437	G	C	MI.11031	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	131	44	G	A	gGg/gCg	7,11	1	0	probably_damaging	1	neutral	0,5	neutral	1,13	deleterious	-5,7	deleterious	-5,42	high_impact	4,24	neutral	0,72	damaging	0,11	deleterious	3,04	22,4	0,03	0,35	disease	0,55	disease	0,84	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,28	high_impact	2,51	0,33	0,8	58,81	10,54	P	0,6	P	0,76	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3437	3437	G	A	MI.11032	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	131	44	G	E	gGg/gAg	7,11	1	0	probably_damaging	1	neutral	0,27	neutral	1,1	deleterious	-6,73	deleterious	-7,23	high_impact	4,93	neutral	0,69	damaging	0,07	deleterious	3,8	23,4	0,02	0,35	disease	0,67	disease	0,91	disease	0,84	disease	0,84	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,03	high_impact	3,12	0,21	0,8	58,81	10,54	P	0,77	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3439	3439	C	A	MI.11033	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	133	45	L	M	Cta/Ata	-8,51	0	0	benign	0,14	neutral	0,22	neutral	2,4	deleterious	-3,27	neutral	-1,64	medium_impact	2,91	neutral	0,8	neutral	0,68	deleterious	3,62	23,2	0,19	0,45	neutral	0,41	disease	0,62	neutral	0,47	neutral	0,48	0	neutral	0,75	deleterious	0,54	neutral	-3	neutral	0,25	medium_impact	-0,01	medium_impact	-0,03	medium_impact	1,35	0,56	0,8	24,21	25,63	N	0,38	N	0,45	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3439	3439	C	G	MI.11034	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	133	45	L	V	Cta/Gta	-8,51	0	0	benign	0,03	neutral	0,51	neutral	2,55	neutral	-1,66	neutral	-2,24	low_impact	1,87	neutral	0,83	neutral	0,8	deleterious	3,26	22,8	0,19	0,45	neutral	0,22	disease	0,67	neutral	0,3	neutral	0,45	1	neutral	0,45	deleterious	0,74	neutral	-6	neutral	0,22	medium_impact	0,67	medium_impact	0,29	medium_impact	0,45	0,49	0,8	24,21	25,63	N	0,33	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3440	3440	T	C	MI.11035	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	134	45	L	P	cTa/cCa	0,22	0,02	0	probably_damaging	0,92	neutral	0,21	neutral	2,35	deleterious	-5,1	deleterious	-5,92	high_impact	4,5	neutral	0,7	neutral	0,48	deleterious	3,83	23,4	0,02	0,35	disease	0,68	disease	0,88	disease	0,76	disease	0,81	6	neutral	0,95	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-1,75	medium_impact	-0,05	high_impact	2,74	0,26	0,8	24,21	25,63	P	0,56	P	0,96	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3440	3440	T	A	MI.11036	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	134	45	L	Q	cTa/cAa	0,22	0,02	0	possibly_damaging	0,89	neutral	0,29	neutral	2,36	deleterious	-4,82	deleterious	-5,13	high_impact	4,5	neutral	0,69	neutral	0,49	deleterious	3,99	23,6	0,03	0,35	disease	0,61	disease	0,85	disease	0,65	disease	0,71	4	neutral	0,91	neutral	0,2	deleterious	1	deleterious	0,79	low_impact	-1,6	medium_impact	0,06	high_impact	2,74	0,15	0,8	24,21	25,63	P	0,52	P	0,95	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3440	3440	T	G	MI.11037	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	134	45	L	R	cTa/cGa	0,22	0,02	0	possibly_damaging	0,89	neutral	0,35	neutral	2,36	deleterious	-4,64	deleterious	-5,15	high_impact	4,5	neutral	0,7	neutral	0,45	deleterious	4,09	23,7	0,02	0,35	neutral	0,5	disease	0,92	disease	0,76	disease	0,81	6	neutral	0,9	neutral	0,23	deleterious	1	deleterious	0,8	low_impact	-1,6	medium_impact	0,12	high_impact	2,74	0,1	0,8	24,21	25,63	N	0,57	P	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3442	3442	C	G	MI.11038	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	136	46	L	V	Cta/Gta	-5,52	0	0	possibly_damaging	0,68	neutral	0,5	neutral	2,43	neutral	-2,47	deleterious	-2,62	medium_impact	3,38	neutral	0,7	damaging	0,12	deleterious	3,32	22,9	0,14	0,4	neutral	0,32	disease	0,7	neutral	0,42	disease	0,51	0	neutral	0,66	neutral	0,41	NA	0	deleterious	0,62	low_impact	-1,06	medium_impact	0,28	medium_impact	1,76	0,48	0,8	56,6	9,86	N	0,28	N	0,84	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3442	3442	C	A	MI.11039	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	136	46	L	M	Cta/Ata	-5,52	0	0	probably_damaging	0,98	neutral	0,22	neutral	2,34	deleterious	-3,97	neutral	-1,72	medium_impact	3,21	neutral	0,75	damaging	0,14	deleterious	3,64	23,2	0,16	0,45	neutral	0,5	disease	0,65	neutral	0,41	neutral	0,48	0	deleterious	0,98	neutral	0,12	deleterious	1	deleterious	0,76	low_impact	-2,34	medium_impact	-0,03	medium_impact	1,62	0,44	0,8	56,6	9,86	N	0,33	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9044	9044	T	G	MI.1104	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	518	173	L	R	cTa/cGa	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	3,48	deleterious	-7,36	deleterious	-5,36	high_impact	4,35	damaging	0,45	damaging	0,12	deleterious	4,23	23,9	0,11	0,65	disease	0,89	disease	0,88	disease	0,73	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,63	0,5	0,9	48,67	8,82	N	0,39	N	0,99	disease_causing	0,93	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3443	3443	T	G	MI.11040	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	137	46	L	R	cTa/cGa	-0,24	0	0	probably_damaging	0,99	neutral	0,35	neutral	2,32	deleterious	-4,69	deleterious	-5,3	high_impact	4,74	neutral	0,81	damaging	0,12	deleterious	4,06	23,7	0,01	0,35	disease	0,63	disease	0,92	disease	0,7	disease	0,78	6	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-2,62	medium_impact	0,12	high_impact	2,95	0,16	0,8	56,6	9,86	P	0,6	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3443	3443	T	C	MI.11041	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	137	46	L	P	cTa/cCa	-0,24	0	0	probably_damaging	0,99	neutral	0,21	neutral	2,33	deleterious	-4,43	deleterious	-6,2	medium_impact	2,69	neutral	0,78	damaging	0,12	deleterious	3,85	23,4	0,01	0,35	disease	0,57	disease	0,77	neutral	0,5	disease	0,53	1	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,87	low_impact	-2,62	medium_impact	-0,05	medium_impact	1,16	0,27	0,8	56,6	9,86	N	0,27	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3443	3443	T	A	MI.11042	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	137	46	L	Q	cTa/cAa	-0,24	0	0	probably_damaging	0,99	neutral	0,29	neutral	2,32	deleterious	-5,17	deleterious	-5,29	high_impact	4,74	neutral	0,75	damaging	0,12	deleterious	4,13	23,8	0,02	0,35	disease	0,65	disease	0,85	disease	0,59	disease	0,69	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-2,62	medium_impact	0,06	high_impact	2,95	0,24	0,8	56,6	9,86	P	0,6	P	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3445	3445	C	A	MI.11043	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	139	47	Q	K	Caa/Aaa	-13,34	0	0	probably_damaging	1	neutral	0,3	neutral	2,34	deleterious	-3,93	deleterious	-3,59	high_impact	4,58	damaging	0,59	damaging	0,04	deleterious	3,83	23,4	0,03	0,35	disease	0,56	disease	0,92	disease	0,81	disease	0,81	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	0,07	high_impact	2,81	0,47	0,8	59,43	10,46	N	0,53	P	0,98	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3445	3445	C	G	MI.11044	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	139	47	Q	E	Caa/Gaa	-13,34	0	0	probably_damaging	1	neutral	0,28	neutral	2,32	deleterious	-4,42	deleterious	-2,69	high_impact	4,93	neutral	0,62	damaging	0,06	deleterious	3,02	22,3	0,06	0,35	disease	0,61	disease	0,81	disease	0,8	disease	0,75	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,05	high_impact	3,12	0,48	0,8	59,43	10,46	P	0,7	P	0,93	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3446	3446	A	G	MI.11045	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	140	47	Q	R	cAa/cGa	4,35	1	0	probably_damaging	1	neutral	0,35	neutral	2,31	deleterious	-4,41	deleterious	-3,59	high_impact	4,93	damaging	0,58	damaging	0,04	deleterious	3,27	22,8	0,04	0,35	disease	0,61	disease	0,92	disease	0,82	disease	0,82	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,12	high_impact	3,12	0,37	0,8	59,43	10,46	P	0,8	P	0,95	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3446	3446	A	T	MI.11046	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	140	47	Q	L	cAa/cTa	4,35	1	0	probably_damaging	1	neutral	0,66	neutral	2,27	deleterious	-5,44	deleterious	-6,28	high_impact	4,24	neutral	0,62	damaging	0,04	deleterious	3,56	23,1	0,02	0,35	disease	0,75	disease	0,92	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	0,44	high_impact	2,51	0,27	0,8	59,43	10,46	P	0,58	P	0,99	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3446	3446	A	C	MI.11047	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	140	47	Q	P	cAa/cCa	4,35	1	0	probably_damaging	1	neutral	0,22	neutral	2,25	deleterious	-6,42	deleterious	-5,39	high_impact	4,38	damaging	0,53	damaging	0,05	deleterious	3,18	22,7	0,02	0,35	disease	0,82	disease	0,91	disease	0,83	disease	0,82	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,92	low_impact	-3,57	medium_impact	-0,03	high_impact	2,64	0,28	0,8	59,43	10,46	P	0,62	P	0,98	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3447	3447	A	T	MI.11048	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	141	47	Q	H	caA/caT	6,65	1	0,02	probably_damaging	1	neutral	0,54	neutral	2,25	deleterious	-4,75	deleterious	-4,49	high_impact	4,12	neutral	0,61	damaging	0,04	deleterious	3,93	23,5	0,03	0,35	disease	0,82	disease	0,86	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,31	high_impact	2,41	0,58	0,8	59,43	10,46	P	0,68	P	0,98	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3447	3447	A	C	MI.11049	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	141	47	Q	H	caA/caC	6,65	1	0,02	probably_damaging	1	neutral	0,54	neutral	2,25	deleterious	-4,75	deleterious	-4,49	high_impact	4,12	neutral	0,61	damaging	0,04	deleterious	3,78	23,4	0,03	0,35	disease	0,82	disease	0,86	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,31	high_impact	2,41	0,58	0,8	59,43	10,46	P	0,67	P	0,98	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9044	9044	T	A	MI.1105	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	518	173	L	Q	cTa/cAa	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	3,49	deleterious	-7,28	deleterious	-5,36	high_impact	4,35	damaging	0,51	damaging	0,14	deleterious	4,18	23,8	0,13	0,65	disease	0,9	disease	0,82	disease	0,61	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,6	low_impact	-1,4	high_impact	2,63	0,59	0,9	48,67	8,82	N	0,35	N	0,98	disease_causing	0,91	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3448	3448	C	T	MI.11050	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	142	48	P	S	Ccc/Tcc	0,91	1	0	probably_damaging	1	neutral	0,4	neutral	2,65	neutral	-1,71	deleterious	-7,28	medium_impact	2,9	damaging	0,51	damaging	0,06	deleterious	3,75	23,3	0,1	0,4	neutral	0,23	disease	0,86	disease	0,55	disease	0,64	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,78	low_impact	-3,57	medium_impact	0,18	medium_impact	1,34	0,15	0,8	60,38	10,42	N	0,38	N	0,74	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3448	3448	C	A	MI.11051	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	142	48	P	T	Ccc/Acc	0,91	1	0	probably_damaging	1	neutral	0,39	neutral	2,62	neutral	-2,01	deleterious	-7,28	medium_impact	3,07	damaging	0,55	damaging	0,05	deleterious	3,74	23,3	0,07	0,35	neutral	0,27	disease	0,85	disease	0,54	disease	0,64	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,79	low_impact	-3,57	medium_impact	0,17	medium_impact	1,49	0,72	0,85	60,38	10,42	N	0,35	N	0,91	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3448	3448	C	G	MI.11052	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	142	48	P	A	Ccc/Gcc	0,91	1	0	probably_damaging	1	neutral	0,5	neutral	2,74	neutral	-1,77	deleterious	-7,28	medium_impact	3,02	damaging	0,57	damaging	0,07	deleterious	2,98	22,2	0,07	0,35	neutral	0,19	disease	0,75	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	0,28	medium_impact	1,45	0,73	0,85	60,38	10,42	N	0,36	N	0,78	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3449	3449	C	G	MI.11053	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	143	48	P	R	cCc/cGc	5,5	1	0	probably_damaging	1	neutral	0,35	neutral	2,57	deleterious	-3,04	deleterious	-8,19	high_impact	4,82	damaging	0,58	damaging	0,04	deleterious	3,54	23,1	0,02	0,35	neutral	0,32	disease	0,93	disease	0,75	disease	0,82	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	0,12	high_impact	3,02	0,39	0,8	60,38	10,42	P	0,68	P	0,71	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3449	3449	C	T	MI.11054	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	143	48	P	L	cCc/cTc	5,5	1	0	probably_damaging	1	neutral	0,67	neutral	2,61	neutral	-1,96	deleterious	-9,1	medium_impact	3,4	damaging	0,6	damaging	0,04	deleterious	4,26	23,9	0,05	0,35	neutral	0,25	disease	0,9	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,78	low_impact	-3,57	medium_impact	0,45	medium_impact	1,78	0,7	0,85	60,38	10,42	N	0,48	N	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3449	3449	C	A	MI.11055	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	143	48	P	H	cCc/cAc	5,5	1	0	probably_damaging	1	neutral	0,54	neutral	2,54	deleterious	-3,91	deleterious	-8,19	high_impact	4,82	damaging	0,57	damaging	0,04	deleterious	4,1	23,7	0,04	0,35	neutral	0,47	disease	0,89	disease	0,75	disease	0,78	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,31	high_impact	3,02	0,35	0,8	60,38	10,42	P	0,7	P	0,69	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3451	3451	T	C	MI.11056	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	145	49	F	L	Ttc/Ctc	-10,81	0	0	benign	0,39	neutral	0,67	neutral	3,01	neutral	1,09	neutral	0,27	neutral_impact	0,78	neutral	0,8	neutral	0,72	deleterious	2,86	21,7	0,15	0,4	neutral	0,12	disease	0,67	neutral	0,27	neutral	0,44	1	neutral	0,31	deleterious	0,64	neutral	-6	neutral	0,26	medium_impact	-0,57	medium_impact	0,45	medium_impact	-0,51	0,75	0,85	19,81	25,29	N	0,25	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3451	3451	T	G	MI.11057	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	145	49	F	V	Ttc/Gtc	-10,81	0	0	benign	0,26	neutral	0,5	neutral	2,87	neutral	0,44	neutral	0,83	neutral_impact	0,76	neutral	0,86	neutral	0,95	deleterious	2,77	21,2	0,05	0,35	neutral	0,16	disease	0,76	neutral	0,27	neutral	0,49	0	neutral	0,4	deleterious	0,62	neutral	-6	neutral	0,24	medium_impact	-0,32	medium_impact	0,28	medium_impact	-0,53	0,35	0,8	19,81	25,29	N	0,26	N	0,74	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3451	3451	T	A	MI.11058	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	145	49	F	I	Ttc/Atc	-10,81	0	0	benign	0,05	neutral	0,4	neutral	2,88	neutral	0,48	neutral	1,43	neutral_impact	-0,41	neutral	0,7	neutral	0,95	neutral	1,59	13,81	0,11	0,4	neutral	0,14	neutral	0,18	neutral	0,18	neutral	0,28	4	neutral	0,56	deleterious	0,68	neutral	-6	neutral	0,11	medium_impact	0,45	medium_impact	0,18	low_impact	-1,55	0,52	0,8	19,81	25,29	N	0,47	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3452	3452	T	A	MI.11059	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	146	49	F	Y	tTc/tAc	-0,7	0	0	possibly_damaging	0,83	neutral	1	neutral	2,63	neutral	-2,93	neutral	-1,19	high_impact	3,56	neutral	0,75	neutral	0,57	deleterious	4,18	23,8	0,1	0,4	neutral	0,23	disease	0,74	disease	0,51	disease	0,58	2	neutral	0,83	deleterious	0,59	deleterious	1	deleterious	0,62	low_impact	-1,4	high_impact	1,96	medium_impact	1,92	0,57	0,8	19,81	25,29	N	0,37	N	0,77	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9046	9046	A	T	MI.1106	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	520	174	I	F	Att/Ttt	-1,72	0	0	probably_damaging	0,99	deleterious	0,01	neutral	4,23	neutral	-1,39	deleterious	-3,23	medium_impact	2,23	neutral	0,7	neutral	0,45	deleterious	3,84	23,4	0,27	0,65	neutral	0,45	disease	0,72	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,73	low_impact	-2,65	medium_impact	-0,84	medium_impact	0,81	0,87	0,9	20,8	19,14	N	0,31	N	0,97	disease_causing	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3452	3452	T	G	MI.11060	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	146	49	F	C	tTc/tGc	-0,7	0	0	probably_damaging	0,98	neutral	0,17	neutral	2,62	deleterious	-3,71	neutral	-2,19	medium_impact	3,21	neutral	0,72	neutral	0,43	deleterious	4,05	23,7	0,03	0,35	disease	0,59	disease	0,88	disease	0,55	disease	0,75	5	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,77	low_impact	-2,34	medium_impact	-0,11	medium_impact	1,62	0,19	0,8	19,81	25,29	N	0,36	N	0,8	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3452	3452	T	C	MI.11061	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	146	49	F	S	tTc/tCc	-0,7	0	0	probably_damaging	0,93	neutral	0,4	neutral	2,64	neutral	-2,67	deleterious	-2,86	medium_impact	3,21	neutral	0,71	neutral	0,52	deleterious	4,19	23,8	0,02	0,35	neutral	0,41	disease	0,82	disease	0,55	disease	0,73	5	neutral	0,93	neutral	0,24	deleterious	1	deleterious	0,74	low_impact	-1,81	medium_impact	0,18	medium_impact	1,62	0,17	0,8	19,81	25,29	N	0,38	N	0,94	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3453	3453	C	G	MI.11062	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	147	49	F	L	ttC/ttG	5,73	0,86	0	benign	0,39	neutral	0,67	neutral	3,01	neutral	1,09	neutral	0,27	neutral_impact	0,78	neutral	0,8	neutral	0,72	deleterious	3,14	22,6	0,15	0,4	neutral	0,12	disease	0,67	neutral	0,27	neutral	0,44	1	neutral	0,31	deleterious	0,64	neutral	-6	neutral	0,26	medium_impact	-0,57	medium_impact	0,45	medium_impact	-0,51	0,75	0,85	19,81	25,29	N	0,36	N	0,66	polymorphism	1	0,01	rs386828907	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3453	3453	C	A	MI.11063	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	147	49	F	L	ttC/ttA	5,73	0,86	0	benign	0,39	neutral	0,67	neutral	3,01	neutral	1,09	neutral	0,27	neutral_impact	0,78	neutral	0,8	neutral	0,72	deleterious	3,47	23	0,15	0,4	neutral	0,12	disease	0,67	neutral	0,27	neutral	0,44	1	neutral	0,31	deleterious	0,64	neutral	-6	neutral	0,26	medium_impact	-0,57	medium_impact	0,45	medium_impact	-0,51	0,75	0,85	19,81	25,29	N	0,36	N	0,66	polymorphism	1	0,01	rs386828907	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3454	3454	G	T	MI.11064	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	148	50	A	S	Gct/Tct	-7,59	0	0	probably_damaging	1	neutral	0,41	neutral	2,58	deleterious	-3,46	deleterious	-2,72	low_impact	1,62	neutral	0,76	damaging	0,18	deleterious	3,58	23,2	0,22	0,45	neutral	0,38	disease	0,58	neutral	0,19	neutral	0,42	2	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,78	low_impact	-3,57	medium_impact	0,19	medium_impact	0,23	0,53	0,8	59,12	10,29	N	0,38	N	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3454	3454	G	A	MI.11065	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	148	50	A	T	Gct/Act	-7,59	0	0	probably_damaging	1	neutral	0,4	neutral	2,57	neutral	-2,92	deleterious	-3,63	high_impact	4,1	neutral	0,78	damaging	0,16	deleterious	4,14	23,8	0,11	0,4	neutral	0,33	disease	0,82	neutral	0,41	disease	0,63	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,18	high_impact	2,39	0,72	0,85	59,12	10,29	N	0,35	N	0,7	polymorphism	1	0,17	.	.	.	.	.	.	COSM1155615	.	.	.	.	.	.	.	.
chrM	3454	3454	G	C	MI.11066	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	148	50	A	P	Gct/Cct	-7,59	0	0	probably_damaging	1	neutral	0,22	neutral	2,51	deleterious	-5,19	deleterious	-4,56	high_impact	4,3	neutral	0,71	damaging	0,07	deleterious	3,73	23,3	0,02	0,35	disease	0,65	disease	0,9	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	-0,03	high_impact	2,57	0,44	0,8	59,12	10,29	N	0,41	N	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3455	3455	C	G	MI.11067	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	149	50	A	G	gCt/gGt	5,96	1	0	probably_damaging	1	neutral	0,36	neutral	2,52	deleterious	-4,31	deleterious	-3,65	medium_impact	3,5	neutral	0,76	damaging	0,1	deleterious	3,9	23,5	0,15	0,45	disease	0,57	disease	0,79	neutral	0,4	disease	0,61	2	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-3,57	medium_impact	0,14	medium_impact	1,87	0,65	0,8	59,12	10,29	P	0,57	P	0,79	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3455	3455	C	A	MI.11068	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	149	50	A	D	gCt/gAt	5,96	1	0	probably_damaging	1	neutral	0,22	neutral	2,52	deleterious	-5,28	deleterious	-5,47	high_impact	4,65	neutral	0,78	damaging	0,1	deleterious	4,38	24,1	0,02	0,35	disease	0,63	disease	0,92	disease	0,67	disease	0,75	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	-0,03	high_impact	2,87	0,33	0,8	59,12	10,29	P	0,63	P	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3455	3455	C	T	MI.11069	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	149	50	A	V	gCt/gTt	5,96	1	0	probably_damaging	1	neutral	0,51	neutral	2,61	neutral	-2,48	deleterious	-3,65	medium_impact	3,45	neutral	0,68	damaging	0,06	deleterious	4,33	24	0,06	0,35	neutral	0,29	disease	0,85	disease	0,52	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,78	low_impact	-3,57	medium_impact	0,29	medium_impact	1,82	0,68	0,85	59,12	10,29	P	0,55	P	0,72	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9046	9046	A	C	MI.1107	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	520	174	I	L	Att/Ctt	-1,72	0	0	probably_damaging	0,93	neutral	0,93	neutral	4,7	neutral	1,25	neutral	-1,46	low_impact	0,9	neutral	0,81	neutral	0,68	deleterious	2,74	21	0,37	0,65	neutral	0,43	neutral	0,28	neutral	0,39	neutral	0,44	1	neutral	0,92	deleterious	0,5	neutral	-2	deleterious	0,61	low_impact	-1,82	medium_impact	0,93	medium_impact	-0,33	0,74	0,9	20,8	19,14	N	0,24	N	0,83	disease_causing	0,6	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3457	3457	G	T	MI.11070	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	151	51	D	Y	Gac/Tac	-5,52	0	0	probably_damaging	1	neutral	1	neutral	1,54	deleterious	-9,02	deleterious	-8,23	high_impact	4,95	neutral	0,67	damaging	0,1	deleterious	3,8	23,4	0,02	0,35	disease	0,92	disease	0,92	disease	0,72	disease	0,82	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,91	low_impact	-3,57	high_impact	1,96	high_impact	3,13	0,14	0,8	60,06	10,34	P	0,57	P	1	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3457	3457	G	A	MI.11071	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	151	51	D	N	Gac/Aac	-5,52	0	0	probably_damaging	1	neutral	0,36	neutral	1,59	deleterious	-6,27	deleterious	-4,56	high_impact	4,4	neutral	0,68	damaging	0,11	deleterious	4,11	23,7	0,16	0,45	disease	0,6	disease	0,85	disease	0,6	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,14	high_impact	2,65	0,51	0,8	60,06	10,34	N	0,46	N	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3457	3457	G	C	MI.11072	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	151	51	D	H	Gac/Cac	-5,52	0	0	probably_damaging	1	neutral	0,55	neutral	1,55	deleterious	-7,29	deleterious	-6,4	high_impact	4,61	neutral	0,66	damaging	0,1	deleterious	3,56	23,1	0,02	0,35	disease	0,85	disease	0,85	disease	0,72	disease	0,79	6	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	0,32	high_impact	2,84	0,45	0,8	60,06	10,34	N	0,43	N	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3458	3458	A	G	MI.11073	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	152	51	D	G	gAc/gGc	7,11	1	0	probably_damaging	1	neutral	0,41	neutral	1,57	deleterious	-7,14	deleterious	-6,4	high_impact	4,61	neutral	0,76	damaging	0,14	deleterious	3,96	23,6	0,03	0,35	disease	0,74	disease	0,85	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,19	high_impact	2,84	0,2	0,8	60,06	10,34	P	0,61	P	0,99	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3458	3458	A	T	MI.11074	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	152	51	D	V	gAc/gTc	7,11	1	0	probably_damaging	1	neutral	0,54	neutral	1,55	deleterious	-8,87	deleterious	-8,23	high_impact	4,95	neutral	0,63	damaging	0,11	deleterious	3,68	23,3	0,02	0,35	disease	0,89	disease	0,91	disease	0,67	disease	0,78	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,31	high_impact	3,13	0,08	0,8	60,06	10,34	P	0,65	P	1	polymorphism	0,99	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3458	3458	A	C	MI.11075	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	152	51	D	A	gAc/gCc	7,11	1	0	probably_damaging	1	neutral	0,61	neutral	1,58	deleterious	-7,04	deleterious	-7,32	high_impact	4,61	neutral	0,68	damaging	0,12	deleterious	3,61	23,2	0,03	0,35	disease	0,74	disease	0,81	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,38	high_impact	2,84	0,25	0,8	60,06	10,34	P	0,6	P	0,94	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3459	3459	C	A	MI.11076	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	153	51	D	E	gaC/gaA	8,49	1	0	probably_damaging	1	neutral	0,38	neutral	1,64	deleterious	-5,26	deleterious	-3,66	high_impact	4,95	neutral	0,72	damaging	0,13	deleterious	4,13	23,8	0,06	0,35	disease	0,53	disease	0,75	disease	0,6	disease	0,66	3	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,16	high_impact	3,13	0,39	0,8	60,06	10,34	P	0,76	P	0,95	polymorphism	0,96	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3459	3459	C	G	MI.11077	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	153	51	D	E	gaC/gaG	8,49	1	0	probably_damaging	1	neutral	0,38	neutral	1,64	deleterious	-5,26	deleterious	-3,66	high_impact	4,95	neutral	0,72	damaging	0,13	deleterious	3,79	23,4	0,06	0,35	disease	0,53	disease	0,75	disease	0,6	disease	0,66	3	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,16	high_impact	3,13	0,39	0,8	60,06	10,34	P	0,76	P	0,95	polymorphism	0,96	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3460	3460	G	T	MI.11078	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	154	52	A	S	Gcc/Tcc	-7,82	0	0,05	probably_damaging	1	neutral	0,6	neutral	2,64	neutral	-2,08	neutral	-0,79	medium_impact	3,36	neutral	0,75	neutral	0,49	deleterious	3,6	23,2	0,2	0,45	neutral	0,35	disease	0,75	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,8	low_impact	-3,57	medium_impact	0,37	medium_impact	1,75	0,48	0,8	60,06	10,07	N	0,37	N	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3460	3460	G	C	MI.11079	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	154	52	A	P	Gcc/Ccc	-7,82	0	0,05	probably_damaging	1	neutral	0,31	neutral	2,56	deleterious	-3,8	deleterious	-2,62	high_impact	4,05	damaging	0,52	damaging	0,27	deleterious	3,77	23,4	0,02	0,35	disease	0,6	disease	0,93	disease	0,76	disease	0,83	7	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,08	high_impact	2,35	0,56	0,8	60,06	10,07	N	0,46	N	0,96	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9046	9046	A	G	MI.1108	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	520	174	I	V	Att/Gtt	-1,72	0	0	probably_damaging	0,93	neutral	0,06	neutral	4,24	neutral	-1,28	neutral	-0,68	low_impact	1,89	neutral	0,76	neutral	0,64	deleterious	2,03	16,41	0,45	0,65	disease	0,66	neutral	0,3	neutral	0,42	disease	0,59	2	deleterious	0,98	neutral	0,07	neutral	-2	deleterious	0,65	low_impact	-1,82	medium_impact	-0,38	medium_impact	0,52	0,72	0,9	20,8	19,14	N	0,45	N	0,77	polymorphism	0,61	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3460	3460	G	A	MI.11080	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	154	52	A	T	Gcc/Acc	-7,82	0	0,05	probably_damaging	1	neutral	0,54	neutral	2,62	neutral	-1,54	neutral	-2,36	medium_impact	3,08	damaging	0,29	neutral	0,45	deleterious	4,24	23,9	0,13	0,4	neutral	0,26	disease	0,72	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,31	medium_impact	1,5	0,78	0,85	60,06	10,07	P	0,86	P	0,7	disease_causing_automatic	0	0,13	rs199476118	Pathogenic|Pathogenic|Pathogenic	Leber's_optic_atrophy|Mitochondrial_complex_I_deficiency|Leigh_syndrome	RCV000010370.4|RCV000010371.2|RCV000143998.2	MedGen:OMIM:SNOMED_CT|MedGen:OMIM|MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	G3460A	LHON	+	+	Cfrm	133
chrM	3461	3461	C	T	MI.11081	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	155	52	A	V	gCc/gTc	5,96	1	0	probably_damaging	1	neutral	0,58	neutral	2,6	neutral	0,03	deleterious	-3,02	medium_impact	2,37	damaging	0,54	neutral	0,52	deleterious	4,43	24,2	0,08	0,35	neutral	0,19	disease	0,81	disease	0,65	disease	0,73	5	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,35	medium_impact	0,88	0,8	0,85	60,06	10,07	P	0,59	P	0,72	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3461	3461	C	A	MI.11082	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	155	52	A	D	gCc/gAc	5,96	1	0	probably_damaging	1	neutral	0,39	neutral	2,57	deleterious	-4,26	neutral	-2,23	high_impact	4,05	damaging	0,59	neutral	0,38	deleterious	4,46	24,2	0,01	0,35	disease	0,56	disease	0,92	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,17	high_impact	2,35	0,25	0,8	60,06	10,07	P	0,7	P	0,98	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3461	3461	C	G	MI.11083	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	155	52	A	G	gCc/gGc	5,96	1	0	probably_damaging	1	neutral	0,44	neutral	2,9	neutral	0,07	neutral	2,87	neutral_impact	-0,2	neutral	0,77	neutral	0,64	neutral	1,18	11,63	0,2	0,45	neutral	0,15	neutral	0,1	neutral	0,32	neutral	0,23	5	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,69	low_impact	-3,57	medium_impact	0,22	low_impact	-1,36	0,62	0,8	60,06	10,07	P	0,59	P	0,79	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3463	3463	A	C	MI.11084	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	157	53	M	L	Ata/Cta	-20	0	0	benign	0,01	neutral	0,66	neutral	3,06	neutral	2,32	neutral	0,46	neutral_impact	-0,6	neutral	0,84	neutral	0,96	neutral	-0,36	0,49	0,26	0,45	neutral	0,19	neutral	0,18	neutral	0,17	neutral	0,27	5	neutral	0,32	deleterious	0,83	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,44	low_impact	-1,71	0,39	0,8	20,75	31,37	N	0,44	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3463	3463	A	G	MI.11085	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	157	53	M	V	Ata/Gta	-20	0	0	benign	0,01	neutral	0,51	neutral	3,05	neutral	2,29	neutral	0,62	neutral_impact	-1,22	neutral	0,77	neutral	0,98	neutral	-1,88	0	0,23	0,45	neutral	0,16	neutral	0,11	neutral	0,17	neutral	0,27	5	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	0,29	low_impact	-2,25	0,36	0,8	20,75	31,37	N	0,46	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3463	3463	A	T	MI.11086	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	157	53	M	L	Ata/Tta	-20	0	0	benign	0,01	neutral	0,66	neutral	3,06	neutral	2,32	neutral	0,46	neutral_impact	-0,6	neutral	0,84	neutral	0,96	neutral	-0,2	1,08	0,26	0,45	neutral	0,19	neutral	0,18	neutral	0,17	neutral	0,27	5	neutral	0,32	deleterious	0,83	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,44	low_impact	-1,71	0,39	0,8	20,75	31,37	N	0,43	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3464	3464	T	C	MI.11087	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	158	53	M	T	aTa/aCa	-3,92	0	0	benign	0,36	neutral	0,41	neutral	2,82	neutral	0,24	neutral	-2,18	low_impact	1,23	neutral	0,86	neutral	0,78	neutral	0,98	10,56	0,09	0,35	neutral	0,16	neutral	0,4	neutral	0,49	neutral	0,45	1	neutral	0,52	deleterious	0,53	neutral	-6	neutral	0,39	medium_impact	-0,52	medium_impact	0,19	medium_impact	-0,11	0,14	0,8	20,75	31,37	N	0,29	N	0,34	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3464	3464	T	A	MI.11088	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	158	53	M	K	aTa/aAa	-3,92	0	0	possibly_damaging	0,6	neutral	0,32	neutral	2,77	neutral	-1,26	deleterious	-3,48	medium_impact	2,55	neutral	0,67	neutral	0,48	deleterious	2,03	16,42	0,03	0,35	neutral	0,24	disease	0,68	disease	0,56	disease	0,71	4	neutral	0,7	neutral	0,36	NA	0	deleterious	0,55	medium_impact	-0,92	medium_impact	0,09	medium_impact	1,04	0,21	0,8	20,75	31,37	N	0,39	N	0,67	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3465	3465	A	T	MI.11089	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	159	53	M	I	atA/atT	4,58	0,65	0	benign	0,17	neutral	0,4	neutral	3,03	neutral	2,2	neutral	0,68	neutral_impact	-1,32	neutral	0,78	neutral	0,99	neutral	-0,16	1,3	0,27	0,45	neutral	0,17	neutral	0,14	neutral	0,14	neutral	0,24	5	neutral	0,52	deleterious	0,62	neutral	-6	neutral	0,17	medium_impact	-0,1	medium_impact	0,18	low_impact	-2,34	0,48	0,8	20,75	31,37	N	0,48	N	0	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9047	9047	T	C	MI.1109	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	521	174	I	T	aTt/aCt	5,68	1	0	probably_damaging	0,99	deleterious	0,01	neutral	4,2	neutral	-1,92	deleterious	-3,35	medium_impact	2,94	neutral	0,84	neutral	0,75	deleterious	2,37	18,64	0,33	0,65	disease	0,85	disease	0,52	neutral	0,47	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,76	low_impact	-2,65	medium_impact	-0,84	medium_impact	1,42	0,62	0,9	20,8	19,14	P	0,51	P	0,99	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3465	3465	A	C	MI.11090	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	159	53	M	I	atA/atC	4,58	0,65	0	benign	0,17	neutral	0,4	neutral	3,03	neutral	2,2	neutral	0,68	neutral_impact	-1,32	neutral	0,78	neutral	0,99	neutral	-0,24	0,9	0,27	0,45	neutral	0,17	neutral	0,14	neutral	0,14	neutral	0,24	5	neutral	0,52	deleterious	0,62	neutral	-6	neutral	0,17	medium_impact	-0,1	medium_impact	0,18	low_impact	-2,34	0,48	0,8	20,75	31,37	N	0,47	N	0	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3466	3466	A	G	MI.11091	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	160	54	K	E	Aaa/Gaa	-2,77	0	0	probably_damaging	1	neutral	0,46	neutral	1,81	deleterious	-6,84	deleterious	-3,67	high_impact	4,61	neutral	0,76	damaging	0,14	deleterious	3,95	23,6	0,05	0,35	disease	0,69	disease	0,75	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,24	high_impact	2,84	0,35	0,8	60,06	10,66	N	0,51	P	0,92	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3466	3466	A	C	MI.11092	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	160	54	K	Q	Aaa/Caa	-2,77	0	0	probably_damaging	1	neutral	0,45	neutral	1,81	deleterious	-6,17	deleterious	-3,67	high_impact	4,96	neutral	0,73	damaging	0,14	deleterious	3,38	22,9	0,09	0,35	disease	0,62	disease	0,77	disease	0,51	disease	0,6	2	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,23	high_impact	3,14	0,41	0,8	60,06	10,66	P	0,68	P	0,92	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3467	3467	A	T	MI.11093	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	161	54	K	M	aAa/aTa	6,65	1	0	probably_damaging	1	neutral	0,25	neutral	1,76	deleterious	-8,87	deleterious	-5,51	high_impact	4,96	neutral	0,82	damaging	0,15	deleterious	3,73	23,3	0,03	0,35	disease	0,89	disease	0,78	disease	0,54	disease	0,71	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,01	high_impact	3,14	0,15	0,8	60,06	10,66	P	0,69	P	0,5	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3467	3467	A	C	MI.11094	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	161	54	K	T	aAa/aCa	6,65	1	0	probably_damaging	1	neutral	0,5	neutral	1,79	deleterious	-7,24	deleterious	-5,51	high_impact	4,96	neutral	0,7	damaging	0,11	deleterious	3,5	23,1	0,05	0,35	disease	0,76	disease	0,75	disease	0,53	disease	0,63	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,28	high_impact	3,14	0,23	0,8	60,06	10,66	P	0,7	P	0,82	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3468	3468	A	C	MI.11095	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	162	54	K	N	aaA/aaC	8,49	1	0	probably_damaging	1	neutral	0,4	neutral	1,79	deleterious	-7,24	deleterious	-4,59	high_impact	4,96	neutral	0,74	damaging	0,11	deleterious	3,71	23,3	0,07	0,35	disease	0,75	disease	0,78	neutral	0,44	disease	0,63	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,18	high_impact	3,14	0,24	0,8	60,06	10,66	P	0,72	P	0,84	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3468	3468	A	T	MI.11096	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	162	54	K	N	aaA/aaT	8,49	1	0	probably_damaging	1	neutral	0,4	neutral	1,79	deleterious	-7,24	deleterious	-4,59	high_impact	4,96	neutral	0,74	damaging	0,11	deleterious	3,76	23,3	0,07	0,35	disease	0,75	disease	0,78	neutral	0,44	disease	0,63	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,18	high_impact	3,14	0,24	0,8	60,06	10,66	P	0,72	P	0,84	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3469	3469	C	T	MI.11097	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	163	55	L	F	Ctc/Ttc	2,06	0,99	0	probably_damaging	1	neutral	0,35	neutral	2,12	deleterious	-3,74	deleterious	-3,65	high_impact	3,67	damaging	0,58	neutral	0,32	deleterious	3,88	23,5	0,08	0,35	neutral	0,48	disease	0,67	disease	0,52	disease	0,57	1	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,12	high_impact	2,02	0,51	0,8	58,81	10,4	P	0,6	P	0,95	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3469	3469	C	A	MI.11098	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	163	55	L	I	Ctc/Atc	2,06	0,99	0	probably_damaging	1	neutral	0,35	neutral	2,18	neutral	-2,85	neutral	-1,82	high_impact	3,77	neutral	0,67	neutral	0,45	deleterious	4,17	23,8	0,17	0,45	neutral	0,43	disease	0,59	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,12	high_impact	2,1	0,55	0,8	58,81	10,4	P	0,62	P	0,83	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3469	3469	C	G	MI.11099	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	163	55	L	V	Ctc/Gtc	2,06	0,99	0	probably_damaging	1	neutral	0,47	neutral	2,17	neutral	-2,97	deleterious	-2,74	high_impact	3,94	neutral	0,6	neutral	0,32	deleterious	3,35	22,9	0,12	0,4	neutral	0,43	disease	0,6	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,25	high_impact	2,25	0,54	0,8	58,81	10,4	P	0,55	P	0,84	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8578	8578	C	A	MI.111	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	52	18	P	T	Ccc/Acc	-12,13	0	0	probably_damaging	1	neutral	0,05	neutral	4,64	neutral	0,92	deleterious	-6,61	medium_impact	2,75	neutral	0,82	neutral	0,69	deleterious	3,45	23	0,35	0,65	neutral	0,32	disease	0,75	disease	0,65	disease	0,64	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	-0,43	medium_impact	1,26	0,79	0,9	21,24	15,57	N	0,37	N	0,42	polymorphism	0,95	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9047	9047	T	A	MI.1110	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	521	174	I	N	aTt/aAt	5,68	1	0	probably_damaging	1	deleterious	0	neutral	4,14	deleterious	-4,2	deleterious	-5,44	high_impact	3,98	neutral	0,72	neutral	0,47	deleterious	4,54	24,3	0,22	0,65	disease	0,94	disease	0,76	disease	0,65	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,6	low_impact	-1,4	high_impact	2,31	0,68	0,9	20,8	19,14	N	0,5	N	1	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3470	3470	T	A	MI.11100	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	164	55	L	H	cTc/cAc	-0,01	0,94	0	probably_damaging	1	neutral	0,33	neutral	2,07	deleterious	-5,87	deleterious	-6,38	high_impact	4,92	neutral	0,62	neutral	0,3	deleterious	4,26	23,9	0,02	0,35	disease	0,83	disease	0,78	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,1	high_impact	3,11	0,3	0,8	58,81	10,4	P	0,65	P	0,97	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3470	3470	T	G	MI.11101	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	164	55	L	R	cTc/cGc	-0,01	0,94	0	probably_damaging	1	neutral	0,61	neutral	2,08	deleterious	-5,19	deleterious	-5,47	high_impact	4,92	neutral	0,64	damaging	0,27	deleterious	4,14	23,8	0,01	0,35	disease	0,76	disease	0,88	disease	0,75	disease	0,79	6	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,38	high_impact	3,11	0,12	0,8	58,81	10,4	P	0,71	P	1	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3470	3470	T	C	MI.11102	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	164	55	L	P	cTc/cCc	-0,01	0,94	0	probably_damaging	1	neutral	0,34	neutral	2,06	deleterious	-6,05	deleterious	-6,39	high_impact	4,57	neutral	0,63	neutral	0,33	deleterious	3,89	23,5	0,01	0,35	disease	0,82	disease	0,8	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	0,11	high_impact	2,8	0,24	0,8	58,81	10,4	P	0,56	P	1	polymorphism	1	0,47	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	3472	3472	T	C	MI.11103	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	166	56	F	L	Ttc/Ctc	-3	0	0	possibly_damaging	0,74	neutral	0,71	neutral	2,86	neutral	1,15	deleterious	-4,87	low_impact	1,66	neutral	0,68	neutral	0,58	deleterious	3,9	23,5	0,19	0,45	neutral	0,12	disease	0,61	neutral	0,26	neutral	0,41	2	neutral	0,69	deleterious	0,49	neutral	-3	deleterious	0,59	low_impact	-1,18	medium_impact	0,49	medium_impact	0,26	0,77	0,85	60,69	10,14	N	0,46	N	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	CPD	0,15	T3472C	LHON	+	-	Reported	2
chrM	3472	3472	T	G	MI.11104	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	166	56	F	V	Ttc/Gtc	-3	0	0	possibly_damaging	0,83	neutral	0,54	neutral	2,82	neutral	-0,19	deleterious	-5,87	medium_impact	2,9	neutral	0,67	neutral	0,64	deleterious	3,97	23,6	0,06	0,35	neutral	0,22	disease	0,83	disease	0,54	disease	0,68	4	neutral	0,81	neutral	0,36	NA	0	deleterious	0,67	low_impact	-1,4	medium_impact	0,31	medium_impact	1,34	0,33	0,8	60,69	10,14	N	0,41	N	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3472	3472	T	A	MI.11105	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	166	56	F	I	Ttc/Atc	-3	0	0	possibly_damaging	0,88	neutral	0,41	neutral	2,8	neutral	-0,29	deleterious	-4,96	medium_impact	2,1	neutral	0,76	neutral	0,72	deleterious	4,32	24	0,12	0,4	neutral	0,18	disease	0,67	neutral	0,42	neutral	0,44	1	neutral	0,88	neutral	0,27	NA	0	deleterious	0,69	low_impact	-1,56	medium_impact	0,19	medium_impact	0,65	0,44	0,8	60,69	10,14	N	0,43	N	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3473	3473	T	A	MI.11106	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	167	56	F	Y	tTc/tAc	2,98	0,99	0	benign	0,12	neutral	1	neutral	2,64	neutral	-2,7	deleterious	-2,61	high_impact	3,92	neutral	0,74	neutral	0,63	deleterious	4,16	23,8	0,13	0,4	neutral	0,49	disease	0,74	neutral	0,46	neutral	0,5	0	neutral	0,12	deleterious	0,94	neutral	-2	neutral	0,28	medium_impact	0,06	high_impact	1,96	high_impact	2,24	0,58	0,8	60,69	10,14	P	0,55	P	0,88	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3473	3473	T	C	MI.11107	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	167	56	F	S	tTc/tCc	2,98	0,99	0	probably_damaging	0,94	neutral	0,47	neutral	2,66	neutral	-2,21	deleterious	-6,92	high_impact	4,62	neutral	0,65	neutral	0,73	deleterious	4,19	23,8	0,02	0,35	neutral	0,41	disease	0,84	disease	0,56	disease	0,68	4	neutral	0,94	neutral	0,27	deleterious	2	deleterious	0,78	low_impact	-1,87	medium_impact	0,25	high_impact	2,85	0,2	0,8	60,69	10,14	P	0,58	P	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3473	3473	T	G	MI.11108	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	167	56	F	C	tTc/tGc	2,98	0,99	0	probably_damaging	0,98	neutral	0,18	neutral	2,63	deleterious	-3,61	deleterious	-6,87	high_impact	4,62	neutral	0,72	neutral	0,57	deleterious	4,04	23,7	0,03	0,35	disease	0,61	disease	0,83	disease	0,57	disease	0,67	3	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,79	low_impact	-2,34	medium_impact	-0,09	high_impact	2,85	0,21	0,8	60,69	10,14	P	0,63	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3474	3474	C	G	MI.11109	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	168	56	F	L	ttC/ttG	7,34	1	0	possibly_damaging	0,74	neutral	0,71	neutral	2,86	neutral	1,15	deleterious	-4,87	low_impact	1,66	neutral	0,68	neutral	0,58	deleterious	4,21	23,9	0,19	0,45	neutral	0,12	disease	0,61	neutral	0,26	neutral	0,41	2	neutral	0,69	deleterious	0,49	neutral	-3	deleterious	0,59	low_impact	-1,18	medium_impact	0,49	medium_impact	0,26	0,77	0,85	60,69	10,14	P	0,55	P	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9047	9047	T	G	MI.1111	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	521	174	I	S	aTt/aGt	5,68	1	0	probably_damaging	0,99	deleterious	0	neutral	4,16	neutral	-2,97	deleterious	-4,52	high_impact	3,98	neutral	0,79	neutral	0,58	deleterious	4,36	24,1	0,21	0,65	disease	0,89	disease	0,77	disease	0,62	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,65	low_impact	-1,4	high_impact	2,31	0,63	0,9	20,8	19,14	P	0,5	N	0,98	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3474	3474	C	A	MI.11110	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	168	56	F	L	ttC/ttA	7,34	1	0	possibly_damaging	0,74	neutral	0,71	neutral	2,86	neutral	1,15	deleterious	-4,87	low_impact	1,66	neutral	0,68	neutral	0,58	deleterious	4,52	24,3	0,19	0,45	neutral	0,12	disease	0,61	neutral	0,26	neutral	0,41	2	neutral	0,69	deleterious	0,49	neutral	-3	deleterious	0,59	low_impact	-1,18	medium_impact	0,49	medium_impact	0,26	0,77	0,85	60,69	10,14	P	0,55	P	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3475	3475	A	C	MI.11111	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	169	57	T	P	Acc/Ccc	-4,38	0	0	probably_damaging	0,93	neutral	0,28	neutral	2,71	neutral	-2,39	deleterious	-2,96	high_impact	3,98	damaging	0,58	damaging	0,1	deleterious	3,42	23	0,04	0,35	disease	0,51	disease	0,8	disease	0,59	disease	0,73	5	neutral	0,95	neutral	0,18	deleterious	2	deleterious	0,76	low_impact	-1,81	medium_impact	0,05	high_impact	2,29	0,34	0,8	13,21	19,45	N	0,35	N	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3475	3475	A	G	MI.11112	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	169	57	T	A	Acc/Gcc	-4,38	0	0	possibly_damaging	0,44	neutral	0,72	neutral	2,79	neutral	-0,17	neutral	-1,41	medium_impact	2,74	neutral	0,65	damaging	0,15	deleterious	3,42	23	0,27	0,45	neutral	0,24	neutral	0,33	neutral	0,34	neutral	0,45	1	neutral	0,34	deleterious	0,64	NA	0	neutral	0,28	medium_impact	-0,65	medium_impact	0,51	medium_impact	1,2	0,32	0,8	13,21	19,45	N	0,28	N	0,33	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3475	3475	A	T	MI.11113	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	169	57	T	S	Acc/Tcc	-4,38	0	0	possibly_damaging	0,71	neutral	0,6	neutral	2,76	neutral	-0,79	neutral	-1,74	low_impact	1,7	neutral	0,81	damaging	0,27	deleterious	3,2	22,7	0,31	0,45	neutral	0,21	neutral	0,41	neutral	0,18	neutral	0,45	1	neutral	0,66	neutral	0,45	neutral	-3	deleterious	0,47	low_impact	-1,12	medium_impact	0,37	medium_impact	0,3	0,56	0,8	13,21	19,45	N	0,38	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3476	3476	C	T	MI.11114	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	170	57	T	I	aCc/aTc	4,58	0,26	0	benign	0,04	neutral	0,45	neutral	2,89	neutral	0,8	neutral	1,28	neutral_impact	0,61	neutral	0,83	neutral	0,94	neutral	1,2	11,74	0,17	0,45	neutral	0,18	neutral	0,11	neutral	0,15	neutral	0,27	5	neutral	0,52	deleterious	0,71	neutral	-6	neutral	0,11	medium_impact	0,55	medium_impact	0,23	medium_impact	-0,66	0,67	0,85	13,21	19,45	N	0,48	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3476	3476	C	A	MI.11115	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	170	57	T	N	aCc/aAc	4,58	0,26	0	possibly_damaging	0,86	neutral	0,43	neutral	2,72	neutral	-1,85	deleterious	-2,67	low_impact	1,86	damaging	0,57	damaging	0,14	deleterious	3,62	23,2	0,33	0,5	neutral	0,37	disease	0,71	neutral	0,44	disease	0,52	0	neutral	0,85	neutral	0,29	neutral	-3	deleterious	0,65	low_impact	-1,49	medium_impact	0,21	medium_impact	0,44	0,66	0,8	13,21	19,45	N	0,37	N	0,76	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3476	3476	C	G	MI.11116	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	170	57	T	S	aCc/aGc	4,58	0,26	0	possibly_damaging	0,71	neutral	0,6	neutral	2,76	neutral	-0,79	neutral	-1,74	low_impact	1,7	neutral	0,81	damaging	0,27	deleterious	3,41	23	0,31	0,45	neutral	0,21	neutral	0,41	neutral	0,18	neutral	0,45	1	neutral	0,66	neutral	0,45	neutral	-3	deleterious	0,47	low_impact	-1,12	medium_impact	0,37	medium_impact	0,3	0,56	0,8	13,21	19,45	N	0,36	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3478	3478	A	C	MI.11117	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	172	58	K	Q	Aaa/Caa	-6,67	0	0	probably_damaging	1	neutral	0,59	neutral	1,81	deleterious	-4,95	deleterious	-3,63	high_impact	4,4	neutral	0,6	damaging	0,09	deleterious	3,37	22,9	0,1	0,4	disease	0,62	disease	0,79	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,36	high_impact	2,65	0,33	0,8	59,75	10,72	N	0,38	N	0,92	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3478	3478	A	G	MI.11118	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	172	58	K	E	Aaa/Gaa	-6,67	0	0	probably_damaging	1	neutral	1	neutral	1,81	deleterious	-5,83	deleterious	-3,63	high_impact	4,6	neutral	0,68	damaging	0,08	deleterious	3,95	23,6	0,06	0,35	disease	0,69	disease	0,77	disease	0,73	disease	0,74	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,84	low_impact	-3,57	high_impact	1,96	high_impact	2,83	0,37	0,8	59,75	10,72	N	0,42	N	0,92	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3479	3479	A	C	MI.11119	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	173	58	K	T	aAa/aCa	8,49	1	0	probably_damaging	1	neutral	0,57	neutral	1,79	deleterious	-6,54	deleterious	-5,43	high_impact	4,95	damaging	0,6	damaging	0,08	deleterious	3,55	23,1	0,05	0,35	disease	0,76	disease	0,76	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,34	high_impact	3,13	0,23	0,8	59,75	10,72	P	0,71	P	0,82	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9048	9048	T	G	MI.1112	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	522	174	I	M	atT/atG	4,76	1	0	probably_damaging	1	neutral	0,09	neutral	4,19	neutral	-2,11	neutral	-2,29	medium_impact	2,32	neutral	0,81	neutral	0,58	deleterious	3,5	23,1	0,39	0,65	disease	0,7	disease	0,54	disease	0,55	disease	0,53	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	-0,28	medium_impact	0,89	0,87	0,9	20,8	19,14	N	0,47	N	0,75	disease_causing	1	0,03	rs386829059	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3479	3479	A	T	MI.11120	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	173	58	K	M	aAa/aTa	8,49	1	0	probably_damaging	1	neutral	0,11	neutral	1,76	deleterious	-8,12	deleterious	-5,44	high_impact	4,6	neutral	0,66	damaging	0,07	deleterious	3,92	23,5	0,04	0,35	disease	0,89	disease	0,79	disease	0,69	disease	0,77	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	-0,23	high_impact	2,83	0,26	0,8	59,75	10,72	P	0,62	P	0,5	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3480	3480	A	C	MI.11121	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	174	58	K	N	aaA/aaC	8,49	1	0,06	probably_damaging	1	neutral	0,49	neutral	1,79	deleterious	-6,26	deleterious	-4,54	high_impact	4,4	neutral	0,62	damaging	0,07	deleterious	3,73	23,3	0,09	0,35	disease	0,74	disease	0,8	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,27	high_impact	2,65	0,25	0,8	59,75	10,72	P	0,62	P	0,84	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3480	3480	A	T	MI.11122	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	174	58	K	N	aaA/aaT	8,49	1	0,06	probably_damaging	1	neutral	0,49	neutral	1,79	deleterious	-6,26	deleterious	-4,54	high_impact	4,4	neutral	0,62	damaging	0,07	deleterious	3,82	23,4	0,09	0,35	disease	0,74	disease	0,8	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,27	high_impact	2,65	0,25	0,8	59,75	10,72	P	0,63	P	0,84	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3481	3481	G	C	MI.11123	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	175	59	E	Q	Gag/Cag	4,58	1	0	probably_damaging	1	neutral	0,58	neutral	1,75	deleterious	-5,04	deleterious	-2,73	high_impact	3,54	neutral	0,68	damaging	0,13	deleterious	3,3	22,9	0,43	0,55	neutral	0,32	disease	0,79	disease	0,62	disease	0,68	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,35	medium_impact	1,9	0,49	0,8	58,49	10,43	N	0,53	P	0,91	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3481	3481	G	A	MI.11124	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	175	59	E	K	Gag/Aag	4,58	1	0	probably_damaging	1	neutral	0,95	neutral	1,77	deleterious	-4,61	deleterious	-3,63	high_impact	3,62	neutral	0,67	damaging	0,09	deleterious	4,44	24,2	0,13	0,4	neutral	0,34	disease	0,87	disease	0,77	disease	0,76	5	deleterious	1	deleterious	0,48	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,99	medium_impact	1,97	0,67	0,85	58,49	10,43	P	0,69	P	0,99	disease_causing_automatic	0	0,31	rs587776433	Pathogenic	Leigh_syndrome	RCV000143999.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	G3481A	Progressive Encephalomyopathy	-	+	Reported	1
chrM	3482	3482	A	C	MI.11125	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	176	59	E	A	gAg/gCg	7,11	1	0	probably_damaging	1	neutral	0,75	neutral	1,75	deleterious	-4,91	deleterious	-5,44	high_impact	4,05	neutral	0,69	damaging	0,14	deleterious	3,5	23,1	0,12	0,4	neutral	0,4	disease	0,65	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,54	high_impact	2,35	0,36	0,8	58,49	10,43	P	0,58	P	0,74	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3482	3482	A	G	MI.11126	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	176	59	E	G	gAg/gGg	7,11	1	0	probably_damaging	1	neutral	0,38	neutral	1,74	deleterious	-5,26	deleterious	-6,36	high_impact	3,88	neutral	0,68	damaging	0,14	deleterious	4,05	23,7	0,13	0,4	neutral	0,48	disease	0,8	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,16	high_impact	2,2	0,21	0,8	58,49	10,43	P	0,62	P	0,61	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3482	3482	A	T	MI.11127	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	176	59	E	V	gAg/gTg	7,11	1	0	probably_damaging	1	neutral	0,3	neutral	1,73	deleterious	-5,97	deleterious	-6,36	high_impact	4,05	neutral	0,63	damaging	0,11	deleterious	4,07	23,7	0,09	0,35	disease	0,58	disease	0,86	disease	0,75	disease	0,78	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,07	high_impact	2,35	0,26	0,8	58,49	10,43	P	0,64	P	0,83	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3483	3483	G	C	MI.11128	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	177	59	E	D	gaG/gaC	8,49	1	0,01	probably_damaging	1	neutral	0,62	neutral	1,8	deleterious	-3,99	deleterious	-2,72	high_impact	4,17	neutral	0,77	damaging	0,14	deleterious	3,6	23,2	0,38	0,5	neutral	0,41	disease	0,75	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,39	high_impact	2,45	0,48	0,8	58,49	10,43	P	0,57	P	0,9	polymorphism	0,98	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3483	3483	G	T	MI.11129	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	177	59	E	D	gaG/gaT	8,49	1	0,01	probably_damaging	1	neutral	0,62	neutral	1,8	deleterious	-3,99	deleterious	-2,72	high_impact	4,17	neutral	0,77	damaging	0,14	deleterious	3,76	23,3	0,38	0,5	neutral	0,41	disease	0,75	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,39	high_impact	2,45	0,48	0,8	58,49	10,43	P	0,57	P	0,9	polymorphism	0,98	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9048	9048	T	A	MI.1113	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	522	174	I	M	atT/atA	4,76	1	0	probably_damaging	1	neutral	0,09	neutral	4,19	neutral	-2,11	neutral	-2,29	medium_impact	2,32	neutral	0,81	neutral	0,58	deleterious	3,75	23,3	0,39	0,65	disease	0,7	disease	0,54	disease	0,55	disease	0,53	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	-0,28	medium_impact	0,89	0,87	0,9	20,8	19,14	P	0,49	N	0,75	disease_causing	1	0,03	rs386829059	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3484	3484	C	T	MI.11130	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	178	60	P	S	Ccc/Tcc	-0,93	0,01	0	probably_damaging	1	neutral	0,73	neutral	2,8	neutral	1,21	deleterious	-7,35	medium_impact	2,44	neutral	0,78	damaging	0,13	deleterious	3,79	23,4	0,27	0,45	neutral	0,17	disease	0,64	neutral	0,22	neutral	0,46	1	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,52	medium_impact	0,94	0,21	0,8	57,55	10,26	N	0,25	N	0,74	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3484	3484	C	A	MI.11131	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	178	60	P	T	Ccc/Acc	-0,93	0,01	0	probably_damaging	1	neutral	0,58	neutral	2,8	neutral	0,89	deleterious	-7,35	low_impact	1,88	neutral	0,66	damaging	0,1	deleterious	3,75	23,3	0,26	0,45	neutral	0,21	disease	0,53	neutral	0,2	neutral	0,42	2	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,69	low_impact	-3,57	medium_impact	0,35	medium_impact	0,45	0,41	0,8	57,55	10,26	N	0,26	N	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3484	3484	C	G	MI.11132	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	178	60	P	A	Ccc/Gcc	-0,93	0,01	0	probably_damaging	1	neutral	0,75	neutral	2,8	neutral	0,48	deleterious	-7,35	medium_impact	3,27	neutral	0,72	damaging	0,14	deleterious	2,99	22,2	0,27	0,45	neutral	0,17	neutral	0,35	neutral	0,43	neutral	0,42	2	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,68	low_impact	-3,57	medium_impact	0,54	medium_impact	1,67	0,55	0,8	57,55	10,26	N	0,29	N	0,78	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3485	3485	C	A	MI.11133	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	179	60	P	H	cCc/cAc	5,5	1	0	probably_damaging	1	neutral	0,14	neutral	2,74	neutral	-0,93	deleterious	-8,27	medium_impact	3,27	neutral	0,72	damaging	0,1	deleterious	3,91	23,5	0,13	0,4	neutral	0,37	disease	0,67	neutral	0,31	neutral	0,48	0	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	-0,17	medium_impact	1,67	0,23	0,8	57,55	10,26	P	0,55	P	0,69	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3485	3485	C	G	MI.11134	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	179	60	P	R	cCc/cGc	5,5	1	0	probably_damaging	1	neutral	0,52	neutral	2,78	neutral	0,37	deleterious	-8,27	medium_impact	3,4	neutral	0,76	damaging	0,1	deleterious	3,5	23,1	0,15	0,4	neutral	0,23	disease	0,79	disease	0,52	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	0,29	medium_impact	1,78	0,28	0,8	57,55	10,26	N	0,44	N	0,71	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3485	3485	C	T	MI.11135	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	179	60	P	L	cCc/cTc	5,5	1	0	probably_damaging	1	neutral	0,36	neutral	2,76	neutral	-0,1	deleterious	-9,19	low_impact	1,86	neutral	0,71	damaging	0,08	deleterious	4,36	24,1	0,18	0,45	neutral	0,31	disease	0,68	neutral	0,33	neutral	0,46	1	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,72	low_impact	-3,57	medium_impact	0,14	medium_impact	0,44	0,43	0,8	57,55	10,26	N	0,47	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3487	3487	C	A	MI.11136	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	181	61	L	M	Cta/Ata	-12,88	0	0	possibly_damaging	0,52	neutral	0,29	neutral	2,67	neutral	-1,75	neutral	-0,79	low_impact	1,07	neutral	0,82	neutral	0,9	deleterious	2,59	20,1	0,25	0,45	neutral	0,23	neutral	0,26	neutral	0,15	neutral	0,45	1	neutral	0,69	neutral	0,39	neutral	-3	neutral	0,31	medium_impact	-0,78	medium_impact	0,06	medium_impact	-0,25	0,5	0,8	18,24	23,26	N	0,52	P	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3487	3487	C	G	MI.11137	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	181	61	L	V	Cta/Gta	-12,88	0	0	possibly_damaging	0,74	neutral	0,47	neutral	2,83	neutral	0,47	neutral	0,51	neutral_impact	0,13	neutral	0,85	neutral	0,72	deleterious	0,84	9,7	0,24	0,45	neutral	0,13	neutral	0,08	neutral	0,11	neutral	0,24	5	neutral	0,73	neutral	0,37	neutral	-3	deleterious	0,48	low_impact	-1,18	medium_impact	0,25	low_impact	-1,08	0,29	0,8	18,24	23,26	N	0,45	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3488	3488	T	A	MI.11138	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	182	61	L	Q	cTa/cAa	-2,08	0	0	probably_damaging	0,96	neutral	0,29	neutral	2,61	deleterious	-3,35	deleterious	-4,12	medium_impact	3,24	neutral	0,72	neutral	0,45	deleterious	4,01	23,6	0,07	0,35	disease	0,54	disease	0,59	neutral	0,46	disease	0,51	0	neutral	0,96	neutral	0,17	deleterious	1	deleterious	0,71	low_impact	-2,05	medium_impact	0,06	medium_impact	1,64	0,1	0,8	18,24	23,26	N	0,42	N	0,86	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3488	3488	T	C	MI.11139	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	182	61	L	P	cTa/cCa	-2,08	0	0	probably_damaging	0,96	neutral	0,22	neutral	2,61	deleterious	-3,39	deleterious	-4,41	medium_impact	2,69	neutral	0,64	neutral	0,34	deleterious	3,84	23,4	0,05	0,35	disease	0,6	disease	0,78	neutral	0,47	disease	0,67	3	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,81	low_impact	-2,05	medium_impact	-0,03	medium_impact	1,16	0,14	0,8	18,24	23,26	N	0,34	N	0,87	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	T3488C	LHON (putative)	+	-	Reported	1
chrM	9049	9049	G	C	MI.1114	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	523	175	G	R	Gga/Cga	-6,12	0	0	probably_damaging	1	deleterious	0,01	neutral	4,32	deleterious	-3,06	deleterious	-4,68	medium_impact	2,46	neutral	0,82	damaging	0,06	deleterious	3,98	23,6	0,12	0,65	disease	0,53	disease	0,9	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,01	0,7	0,9	44,25	8,03	N	0,24	N	0,98	polymorphism	0,78	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3488	3488	T	G	MI.11140	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	182	61	L	R	cTa/cGa	-2,08	0	0	probably_damaging	0,94	neutral	0,31	neutral	2,61	deleterious	-3,04	deleterious	-4,45	medium_impact	2,69	neutral	0,67	neutral	0,41	deleterious	4,09	23,7	0,05	0,35	disease	0,51	disease	0,77	disease	0,55	disease	0,75	5	neutral	0,95	neutral	0,19	deleterious	1	deleterious	0,77	low_impact	-1,87	medium_impact	0,08	medium_impact	1,16	0,12	0,8	18,24	23,26	N	0,32	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3490	3490	A	G	MI.11141	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	184	62	K	E	Aaa/Gaa	-3	0	0	benign	0,18	neutral	1	neutral	2,77	neutral	-0,79	neutral	-1,36	medium_impact	1,95	neutral	0,84	neutral	0,7	deleterious	3,92	23,5	0,26	0,45	neutral	0,24	disease	0,64	neutral	0,43	disease	0,5	0	neutral	0,18	deleterious	0,91	neutral	-3	neutral	0,27	medium_impact	-0,13	high_impact	1,96	medium_impact	0,52	0,42	0,8	26,73	39,85	N	0,25	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3490	3490	A	C	MI.11142	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	184	62	K	Q	Aaa/Caa	-3	0	0	benign	0,02	neutral	0,59	neutral	2,76	neutral	-0,67	neutral	-0,29	low_impact	1,32	neutral	0,82	neutral	0,97	deleterious	2,2	17,49	0,39	0,5	neutral	0,27	neutral	0,33	neutral	0,25	neutral	0,44	1	neutral	0,38	deleterious	0,79	neutral	-6	neutral	0,16	medium_impact	0,84	medium_impact	0,36	medium_impact	-0,04	0,36	0,8	26,73	39,85	N	0,36	N	0,59	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3491	3491	A	C	MI.11143	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	185	62	K	T	aAa/aCa	0,22	0	0	benign	0,41	neutral	0,59	neutral	2,81	neutral	1,17	deleterious	-2,5	neutral_impact	0,55	neutral	0,69	neutral	0,66	deleterious	3,51	23,1	0,14	0,4	neutral	0,16	neutral	0,37	neutral	0,38	neutral	0,43	1	neutral	0,37	deleterious	0,59	neutral	-6	neutral	0,37	medium_impact	-0,6	medium_impact	0,36	medium_impact	-0,71	0,2	0,8	26,73	39,85	N	0,3	N	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3491	3491	A	T	MI.11144	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	185	62	K	M	aAa/aTa	0,22	0	0	possibly_damaging	0,58	neutral	0,12	neutral	2,74	neutral	-0,08	neutral	-2,33	low_impact	1,05	neutral	0,71	neutral	0,61	deleterious	3,74	23,3	0,12	0,4	neutral	0,3	neutral	0,45	neutral	0,28	neutral	0,49	0	neutral	0,88	neutral	0,27	neutral	-3	deleterious	0,5	medium_impact	-0,88	medium_impact	-0,21	medium_impact	-0,27	0,19	0,8	26,73	39,85	N	0,41	N	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3492	3492	A	T	MI.11145	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	186	62	K	N	aaA/aaT	0,45	0	0	benign	0,26	neutral	0,51	neutral	2,75	neutral	-1,09	neutral	-1,59	low_impact	1,29	neutral	0,68	neutral	0,67	deleterious	3,82	23,4	0,5	0,6	neutral	0,3	disease	0,52	neutral	0,28	disease	0,5	0	neutral	0,39	deleterious	0,63	neutral	-6	neutral	0,38	medium_impact	-0,32	medium_impact	0,29	medium_impact	-0,06	0,34	0,8	26,73	39,85	N	0,38	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3492	3492	A	C	MI.11146	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	186	62	K	N	aaA/aaC	0,45	0	0	benign	0,26	neutral	0,51	neutral	2,75	neutral	-1,09	neutral	-1,59	low_impact	1,29	neutral	0,68	neutral	0,67	deleterious	3,75	23,3	0,5	0,6	neutral	0,3	disease	0,52	neutral	0,28	disease	0,5	0	neutral	0,39	deleterious	0,63	neutral	-6	neutral	0,38	medium_impact	-0,32	medium_impact	0,29	medium_impact	-0,06	0,34	0,8	26,73	39,85	N	0,38	N	0,59	polymorphism	1	0,02	rs878950749	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3493	3493	C	G	MI.11147	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	187	63	P	A	Ccc/Gcc	-5,07	0	0	probably_damaging	1	neutral	0,87	neutral	1,22	deleterious	-5,75	deleterious	-7,38	high_impact	4,07	neutral	0,71	damaging	0,13	deleterious	3,04	22,4	0,15	0,4	neutral	0,43	disease	0,57	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	0,74	high_impact	2,37	0,51	0,8	60,06	10,55	N	0,28	N	0,78	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3493	3493	C	A	MI.11148	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	187	63	P	T	Ccc/Acc	-5,07	0	0	probably_damaging	1	neutral	0,68	neutral	1,19	deleterious	-6,45	deleterious	-7,38	high_impact	3,87	neutral	0,77	damaging	0,11	deleterious	3,79	23,4	0,16	0,45	disease	0,53	disease	0,77	disease	0,56	disease	0,66	3	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,46	high_impact	2,19	0,38	0,8	60,06	10,55	N	0,26	N	0,91	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3493	3493	C	T	MI.11149	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	187	63	P	S	Ccc/Tcc	-5,07	0	0	probably_damaging	1	neutral	0,76	neutral	1,21	deleterious	-6,02	deleterious	-7,38	medium_impact	3,13	neutral	0,73	damaging	0,12	deleterious	3,78	23,4	0,19	0,45	neutral	0,36	disease	0,81	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,79	low_impact	-3,57	medium_impact	0,56	medium_impact	1,55	0,05	0,8	60,06	10,55	N	0,27	N	0,74	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9049	9049	G	T	MI.1115	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	523	175	G	W	Gga/Tga	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	4,29	deleterious	-4,73	deleterious	-5,34	medium_impact	3,01	neutral	0,87	damaging	0,07	deleterious	4,46	24,2	0,13	0,65	disease	0,91	disease	0,9	disease	0,67	disease	0,82	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,85	low_impact	-3,6	low_impact	-1,4	medium_impact	1,48	0,41	0,9	44,25	8,03	N	0,28	N	0,99	polymorphism	0,69	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3494	3494	C	T	MI.11150	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	188	63	P	L	cCc/cTc	5,5	0,99	0	probably_damaging	1	neutral	0,79	neutral	1,19	deleterious	-6,82	deleterious	-9,22	medium_impact	2,54	neutral	0,68	damaging	0,09	deleterious	4,23	23,9	0,11	0,4	neutral	0,49	disease	0,84	disease	0,58	disease	0,51	0	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,81	low_impact	-3,57	medium_impact	0,6	medium_impact	1,03	0,67	0,85	60,06	10,55	N	0,43	N	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3494	3494	C	A	MI.11151	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	188	63	P	H	cCc/cAc	5,5	0,99	0	probably_damaging	1	neutral	0,59	neutral	1,17	deleterious	-8,08	deleterious	-8,3	high_impact	4,42	neutral	0,69	damaging	0,1	deleterious	4,03	23,6	0,09	0,35	disease	0,79	disease	0,82	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,36	high_impact	2,67	0,22	0,8	60,06	10,55	P	0,58	P	0,69	polymorphism	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3494	3494	C	G	MI.11152	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	188	63	P	R	cCc/cGc	5,5	0,99	0	probably_damaging	1	neutral	0,6	neutral	1,18	deleterious	-6,98	deleterious	-8,3	high_impact	4,76	neutral	0,74	damaging	0,1	deleterious	3,53	23,1	0,06	0,35	disease	0,67	disease	0,87	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,37	high_impact	2,97	0,25	0,8	60,06	10,55	P	0,71	P	0,71	polymorphism	0,99	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3496	3496	G	A	MI.11153	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	190	64	A	T	Gcc/Acc	-9,89	0	0,02	benign	0	neutral	0,72	neutral	2,71	neutral	-0,92	neutral	0,01	neutral_impact	-0,51	neutral	0,76	neutral	0,74	neutral	0,9	10,05	0,34	0,5	neutral	0,18	neutral	0,17	neutral	0,14	neutral	0,28	4	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,51	low_impact	-1,63	0,55	0,8	25,16	39,11	N	0,46	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	COSM5653109	.	.	.	.	.	.	.	.
chrM	3496	3496	G	T	MI.11154	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	190	64	A	S	Gcc/Tcc	-9,89	0	0,02	benign	0	neutral	0,81	neutral	2,79	neutral	-0,3	neutral	1,31	neutral_impact	-0,84	neutral	0,68	neutral	0,95	neutral	-1,03	0,01	0,42	0,55	neutral	0,13	neutral	0,06	neutral	0,11	neutral	0,21	6	neutral	0,19	deleterious	0,91	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,63	low_impact	-1,92	0,39	0,8	25,16	39,11	N	0,44	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	G3496T	LHON	+	-	Reported/Secondary	2
chrM	3496	3496	G	C	MI.11155	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	190	64	A	P	Gcc/Ccc	-9,89	0	0,02	benign	0,11	neutral	0,35	neutral	2,65	neutral	-2,44	neutral	-1,97	low_impact	1,13	neutral	0,67	neutral	0,37	deleterious	0,76	9,24	0,17	0,45	neutral	0,29	disease	0,77	neutral	0,28	disease	0,58	1	neutral	0,6	deleterious	0,62	neutral	-6	neutral	0,26	medium_impact	0,1	medium_impact	0,12	medium_impact	-0,2	0,37	0,8	25,16	39,11	N	0,38	N	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3497	3497	C	T	MI.11156	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	191	64	A	V	gCc/gTc	-2,08	0	0,07	benign	0,01	neutral	0,49	neutral	2,71	neutral	-2,06	neutral	-1,4	low_impact	1,36	neutral	0,75	neutral	0,71	neutral	1,25	11,99	0,27	0,45	neutral	0,16	neutral	0,37	neutral	0,17	neutral	0,44	1	neutral	0,49	deleterious	0,74	neutral	-6	neutral	0,12	medium_impact	1,12	medium_impact	0,27	medium_impact	0	0,47	0,8	25,16	39,11	N	0,44	N	0,45	polymorphism	1	0,02	rs200319905	.	.	.	.	.	.	.	.	C3497T	LHON	+	-	Reported/Secondary	3
chrM	3497	3497	C	A	MI.11157	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	191	64	A	D	gCc/gAc	-2,08	0	0,07	benign	0,06	neutral	0,61	neutral	2,7	neutral	-1,26	neutral	-1,71	low_impact	1,34	neutral	0,73	neutral	0,41	neutral	1,42	12,87	0,15	0,4	neutral	0,22	disease	0,7	neutral	0,37	neutral	0,48	0	neutral	0,32	deleterious	0,78	neutral	-6	neutral	0,18	medium_impact	0,37	medium_impact	0,38	medium_impact	-0,02	0,17	0,8	25,16	39,11	N	0,29	N	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3497	3497	C	G	MI.11158	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	191	64	A	G	gCc/gGc	-2,08	0	0,07	benign	0,04	neutral	0,47	neutral	2,67	neutral	-1,52	neutral	-1,65	low_impact	1,44	neutral	0,68	neutral	0,54	deleterious	0,82	9,59	0,39	0,5	neutral	0,32	neutral	0,42	neutral	0,25	neutral	0,47	1	neutral	0,49	deleterious	0,72	neutral	-6	neutral	0,14	medium_impact	0,55	medium_impact	0,25	medium_impact	0,07	0,52	0,8	25,16	39,11	N	0,44	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3499	3499	A	C	MI.11159	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	193	65	T	P	Aca/Cca	-5,52	0	0	probably_damaging	0,91	neutral	0,47	neutral	2,7	neutral	-2,18	deleterious	-4,06	medium_impact	2,38	neutral	0,74	damaging	0,15	deleterious	3,37	22,9	0,08	0,35	neutral	0,44	disease	0,79	neutral	0,35	disease	0,6	2	neutral	0,9	neutral	0,28	deleterious	1	deleterious	0,73	low_impact	-1,69	medium_impact	0,25	medium_impact	0,89	0,4	0,8	30,5	9,69	N	0,27	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9050	9050	G	A	MI.1116	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	524	175	G	E	gGa/gAa	2,44	0,99	0	probably_damaging	1	deleterious	0,03	neutral	4,34	deleterious	-3,05	deleterious	-4,46	medium_impact	2,12	neutral	0,86	damaging	0,08	deleterious	3,94	23,5	0,17	0,65	neutral	0,43	disease	0,88	disease	0,73	disease	0,8	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,81	low_impact	-3,6	medium_impact	-0,56	medium_impact	0,72	0,69	0,9	44,25	8,03	N	0,34	N	1	disease_causing	0,95	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3499	3499	A	G	MI.11160	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	193	65	T	A	Aca/Gca	-5,52	0	0	benign	0,05	neutral	0,71	neutral	2,78	neutral	-0,1	deleterious	-3,19	medium_impact	2,11	neutral	0,83	neutral	0,74	deleterious	2,26	17,93	0,25	0,45	neutral	0,2	neutral	0,29	neutral	0,34	neutral	0,43	1	neutral	0,21	deleterious	0,83	neutral	-3	neutral	0,13	medium_impact	0,45	medium_impact	0,49	medium_impact	0,65	0,27	0,8	30,5	9,69	N	0,3	N	0,65	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3499	3499	A	T	MI.11161	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	193	65	T	S	Aca/Tca	-5,52	0	0	benign	0,13	neutral	0,72	neutral	2,81	neutral	-0,26	neutral	-1,98	low_impact	0,82	neutral	0,81	neutral	0,66	deleterious	1,96	15,95	0,42	0,55	neutral	0,18	neutral	0,36	neutral	0,22	neutral	0,44	1	neutral	0,16	deleterious	0,8	neutral	-6	neutral	0,17	medium_impact	0,02	medium_impact	0,51	medium_impact	-0,47	0,48	0,8	30,5	9,69	N	0,3	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3500	3500	C	T	MI.11162	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	194	65	T	M	aCa/aTa	2,98	0,72	0	probably_damaging	0,95	neutral	0,17	neutral	2,71	neutral	-2,68	deleterious	-4,09	low_impact	1,78	neutral	0,77	damaging	0,16	deleterious	3,96	23,6	0,2	0,45	neutral	0,45	neutral	0,41	neutral	0,25	neutral	0,47	1	neutral	0,97	neutral	0,11	neutral	-2	deleterious	0,65	low_impact	-1,95	medium_impact	-0,11	medium_impact	0,37	0,35	0,8	30,5	9,69	N	0,34	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3500	3500	C	A	MI.11163	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	194	65	T	K	aCa/aAa	2,98	0,72	0	possibly_damaging	0,76	neutral	0,92	neutral	2,82	neutral	0,17	deleterious	-3,83	low_impact	1,4	neutral	0,69	damaging	0,11	deleterious	4,43	24,2	0,13	0,4	neutral	0,17	disease	0,71	neutral	0,43	disease	0,52	0	neutral	0,73	deleterious	0,58	neutral	-3	deleterious	0,61	low_impact	-1,22	medium_impact	0,87	medium_impact	0,03	0,38	0,8	30,5	9,69	N	0,28	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3502	3502	T	C	MI.11164	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	196	66	S	P	Tct/Cct	-3,92	0	0	probably_damaging	1	neutral	0,52	neutral	2,44	deleterious	-3,82	deleterious	-4,09	high_impact	4,21	neutral	0,68	damaging	0,13	deleterious	3,88	23,5	0,07	0,35	disease	0,71	disease	0,74	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,29	high_impact	2,49	0,08	0,8	16,67	30,3	N	0,36	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3502	3502	T	A	MI.11165	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	196	66	S	T	Tct/Act	-3,92	0	0	probably_damaging	1	neutral	0,74	neutral	2,5	neutral	-2,31	neutral	-2,24	medium_impact	3,21	neutral	0,84	neutral	0,76	deleterious	2,63	20,4	0,36	0,5	neutral	0,42	neutral	0,45	disease	0,59	neutral	0,45	1	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,53	medium_impact	1,62	0,48	0,8	16,67	30,3	N	0,34	N	0,08	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3502	3502	T	G	MI.11166	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	196	66	S	A	Tct/Gct	-3,92	0	0	probably_damaging	1	neutral	0,84	neutral	2,75	neutral	-0,27	neutral	-1,84	low_impact	1,25	neutral	0,88	neutral	0,81	deleterious	2,38	18,69	0,44	0,55	neutral	0,16	neutral	0,08	neutral	0,35	neutral	0,27	5	deleterious	1	neutral	0,42	neutral	-2	deleterious	0,66	low_impact	-3,57	medium_impact	0,68	medium_impact	-0,1	0,29	0,8	16,67	30,3	N	0,35	N	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3503	3503	C	T	MI.11167	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	197	66	S	F	tCt/tTt	1,6	0,95	0	probably_damaging	1	neutral	0,43	neutral	2,42	deleterious	-4,58	deleterious	-5,02	medium_impact	3,36	damaging	0,59	damaging	0,1	deleterious	4,07	23,7	0,06	0,35	disease	0,83	disease	0,72	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,82	low_impact	-3,57	medium_impact	0,21	medium_impact	1,75	0,02	0,8	16,67	30,3	N	0,43	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3503	3503	C	G	MI.11168	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	197	66	S	C	tCt/tGt	1,6	0,95	0	probably_damaging	1	neutral	0,13	neutral	2,42	deleterious	-4,52	deleterious	-3,95	high_impact	4,21	neutral	0,69	damaging	0,12	deleterious	3,46	23	0,07	0,35	disease	0,78	disease	0,61	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	-0,19	high_impact	2,49	0,11	0,8	16,67	30,3	P	0,53	P	0,5	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3503	3503	C	A	MI.11169	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	197	66	S	Y	tCt/tAt	1,6	0,95	0	probably_damaging	1	neutral	0,66	neutral	2,42	deleterious	-4,76	deleterious	-5,02	high_impact	3,66	neutral	0,73	damaging	0,13	deleterious	4,07	23,7	0,06	0,35	disease	0,85	disease	0,69	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,44	high_impact	2,01	0,06	0,8	16,67	30,3	N	0,44	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9050	9050	G	T	MI.1117	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	524	175	G	V	gGa/gTa	2,44	0,99	0	probably_damaging	1	deleterious	0,01	neutral	4,43	neutral	-1,2	deleterious	-5,33	medium_impact	2,12	neutral	0,86	damaging	0,09	deleterious	3,81	23,4	0,18	0,65	neutral	0,36	disease	0,83	disease	0,63	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,74	low_impact	-3,6	medium_impact	-0,84	medium_impact	0,72	0,56	0,9	44,25	8,03	N	0,33	N	0,99	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3505	3505	A	T	MI.11170	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	199	67	T	S	Acc/Tcc	-7,59	0	0,04	benign	0,04	neutral	0,95	neutral	2,98	neutral	1,77	neutral	2,53	neutral_impact	-2,42	neutral	0,61	neutral	0,85	neutral	1,03	10,82	0,43	0,55	neutral	0,18	neutral	0,03	neutral	0,16	neutral	0,23	5	neutral	0,01	deleterious	0,96	neutral	-6	neutral	0,1	medium_impact	0,55	medium_impact	0,99	low_impact	-3,3	0,38	0,8	23,58	35,6	N	0,42	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3505	3505	A	C	MI.11171	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	199	67	T	P	Acc/Ccc	-7,59	0	0,04	possibly_damaging	0,75	neutral	0,44	neutral	2,76	neutral	-1,41	neutral	-1,97	low_impact	1,65	damaging	0,55	neutral	0,47	deleterious	3,9	23,5	0,09	0,35	neutral	0,22	disease	0,7	disease	0,56	disease	0,68	4	neutral	0,75	neutral	0,35	neutral	-3	deleterious	0,66	low_impact	-1,2	medium_impact	0,22	medium_impact	0,25	0,28	0,8	23,58	35,6	N	0,36	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3505	3505	A	G	MI.11172	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	199	67	T	A	Acc/Gcc	-7,59	0	0,04	benign	0,01	neutral	1	neutral	2,82	neutral	0,2	neutral	-0,14	neutral_impact	0,45	neutral	0,67	neutral	0,89	deleterious	3,88	23,5	0,32	0,5	neutral	0,15	neutral	0,17	neutral	0,32	neutral	0,31	4	neutral	0,01	deleterious	1	neutral	-6	neutral	0,12	medium_impact	1,12	high_impact	1,96	medium_impact	-0,8	0,28	0,8	23,58	35,6	N	0,31	N	0,18	polymorphism	1	0,01	rs28358585	Benign	not_specified	RCV000238711.1	MedGen	pancreatic cancer cell line, prostate tumor	.	.	.	.	.	.	.	.	.
chrM	3506	3506	C	G	MI.11173	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	200	67	T	S	aCc/aGc	2,98	0,98	0	benign	0,04	neutral	0,95	neutral	2,98	neutral	1,77	neutral	2,53	neutral_impact	-2,42	neutral	0,61	neutral	0,85	deleterious	0,7	8,81	0,43	0,55	neutral	0,18	neutral	0,03	neutral	0,16	neutral	0,23	5	neutral	0,01	deleterious	0,96	neutral	-6	neutral	0,1	medium_impact	0,55	medium_impact	0,99	low_impact	-3,3	0,38	0,8	23,58	35,6	N	0,46	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3506	3506	C	A	MI.11174	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	200	67	T	N	aCc/aAc	2,98	0,98	0	possibly_damaging	0,61	neutral	0,65	neutral	2,89	neutral	1,03	neutral	-0,18	neutral_impact	-1,29	damaging	0,58	neutral	0,66	deleterious	3,55	23,1	0,43	0,55	neutral	0,14	neutral	0,21	neutral	0,22	neutral	0,34	3	neutral	0,54	deleterious	0,52	neutral	-3	neutral	0,36	medium_impact	-0,93	medium_impact	0,43	low_impact	-2,32	0,46	0,8	23,58	35,6	N	0,48	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3506	3506	C	T	MI.11175	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	200	67	T	I	aCc/aTc	2,98	0,98	0	possibly_damaging	0,61	neutral	0,52	neutral	2,75	neutral	-1,76	deleterious	-2,84	low_impact	0,84	damaging	0,55	neutral	0,62	deleterious	3,88	23,5	0,19	0,45	neutral	0,36	neutral	0,34	disease	0,56	neutral	0,47	1	neutral	0,58	neutral	0,46	neutral	-3	neutral	0,41	medium_impact	-0,93	medium_impact	0,29	medium_impact	-0,46	0,42	0,8	23,58	35,6	P	0,53	P	0,84	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3508	3508	A	C	MI.11176	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	202	68	I	L	Atc/Ctc	-10,81	0	0	benign	0,05	neutral	0,6	neutral	2,8	neutral	0,16	neutral	0,04	neutral_impact	-0,67	neutral	0,86	neutral	0,94	deleterious	0,62	8,32	0,29	0,45	neutral	0,19	neutral	0,26	neutral	0,34	neutral	0,41	2	neutral	0,34	deleterious	0,78	neutral	-6	neutral	0,13	medium_impact	0,45	medium_impact	0,37	low_impact	-1,77	0,52	0,8	20,75	15,63	N	0,29	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3508	3508	A	G	MI.11177	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	202	68	I	V	Atc/Gtc	-10,81	0	0	benign	0,05	neutral	0,49	neutral	2,8	neutral	-0,02	neutral	0,5	neutral_impact	-0,14	neutral	0,83	neutral	0,91	deleterious	-0,04	2,24	0,31	0,45	neutral	0,2	neutral	0,16	neutral	0,36	neutral	0,3	4	neutral	0,46	deleterious	0,72	neutral	-6	neutral	0,12	medium_impact	0,45	medium_impact	0,27	low_impact	-1,31	0,44	0,8	20,75	15,63	N	0,35	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3508	3508	A	T	MI.11178	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	202	68	I	F	Atc/Ttc	-10,81	0	0	possibly_damaging	0,49	neutral	0,36	neutral	2,76	neutral	-0,86	neutral	-1,15	neutral_impact	-0,58	neutral	0,85	neutral	0,61	deleterious	1,94	15,82	0,17	0,45	neutral	0,19	neutral	0,37	neutral	0,26	neutral	0,44	1	neutral	0,61	neutral	0,44	neutral	-3	neutral	0,32	medium_impact	-0,74	medium_impact	0,14	low_impact	-1,7	0,49	0,8	20,75	15,63	N	0,37	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3509	3509	T	A	MI.11179	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	203	68	I	N	aTc/aAc	0,22	0	0	benign	0,11	neutral	0,63	neutral	2,79	neutral	0,1	neutral	-0,15	neutral_impact	0,43	neutral	0,84	neutral	0,71	deleterious	2,34	18,41	0,14	0,4	neutral	0,26	disease	0,64	neutral	0,45	disease	0,51	0	neutral	0,27	deleterious	0,76	neutral	-6	neutral	0,19	medium_impact	0,1	medium_impact	0,4	medium_impact	-0,81	0,2	0,8	20,75	15,63	N	0,25	N	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9050	9050	G	C	MI.1118	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	524	175	G	A	gGa/gCa	2,44	0,99	0	probably_damaging	1	neutral	0,62	neutral	4,59	neutral	0,16	deleterious	-2,53	neutral_impact	-0,12	neutral	0,82	neutral	0,39	deleterious	0,83	9,64	0,41	0,65	neutral	0,29	neutral	0,28	neutral	0,35	neutral	0,43	1	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,41	low_impact	-1,2	0,72	0,9	44,25	8,03	N	0,3	N	0,79	disease_causing	0,88	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3509	3509	T	C	MI.11180	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	203	68	I	T	aTc/aCc	0,22	0	0	benign	0	neutral	0,76	neutral	2,81	neutral	0,32	neutral	0,88	neutral_impact	-0,3	neutral	0,76	neutral	0,98	neutral	-0,15	1,39	0,19	0,45	neutral	0,19	neutral	0,23	neutral	0,32	neutral	0,41	2	neutral	0,24	deleterious	0,88	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,56	low_impact	-1,45	0,26	0,8	20,75	15,63	N	0,31	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3509	3509	T	G	MI.11181	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	203	68	I	S	aTc/aGc	0,22	0	0	benign	0,01	neutral	0,98	neutral	2,82	neutral	0,79	neutral	0,64	neutral_impact	-0,12	neutral	0,8	neutral	0,88	neutral	1,1	11,21	0,1	0,4	neutral	0,19	disease	0,5	neutral	0,35	neutral	0,43	1	neutral	0	deleterious	0,99	neutral	-6	neutral	0,12	medium_impact	1,12	medium_impact	1,22	low_impact	-1,29	0,27	0,8	20,75	15,63	N	0,23	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3510	3510	C	G	MI.11182	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	204	68	I	M	atC/atG	-0,47	0	0	possibly_damaging	0,68	neutral	0,22	neutral	2,75	neutral	-1,1	neutral	0,71	neutral_impact	0,43	neutral	0,79	neutral	0,85	deleterious	0,38	6,44	0,37	0,5	neutral	0,22	neutral	0,25	neutral	0,3	neutral	0,44	1	neutral	0,82	neutral	0,27	neutral	-3	neutral	0,42	low_impact	-1,06	medium_impact	-0,03	medium_impact	-0,81	0,46	0,8	20,75	15,63	N	0,42	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3510	3510	C	A	MI.11183	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	204	68	I	M	atC/atA	-0,47	0	0	possibly_damaging	0,68	neutral	0,22	neutral	2,75	neutral	-1,1	neutral	0,71	neutral_impact	0,43	neutral	0,79	neutral	0,85	deleterious	0,83	9,62	0,37	0,5	neutral	0,22	neutral	0,25	neutral	0,3	neutral	0,44	1	neutral	0,82	neutral	0,27	neutral	-3	neutral	0,42	low_impact	-1,06	medium_impact	-0,03	medium_impact	-0,81	0,46	0,8	20,75	15,63	N	0,41	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3511	3511	A	T	MI.11184	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	205	69	T	S	Acc/Tcc	-7,36	0	0	benign	0,02	neutral	0,55	neutral	2,78	neutral	-0,19	neutral	-1,2	neutral_impact	0,58	neutral	0,84	neutral	0,98	neutral	-0,21	1,02	0,41	0,5	neutral	0,13	neutral	0,19	neutral	0,34	neutral	0,36	3	neutral	0,42	deleterious	0,77	neutral	-6	neutral	0,12	medium_impact	0,84	medium_impact	0,32	medium_impact	-0,68	0,66	0,8	27,67	19,61	N	0,33	N	0	polymorphism	1	0,03	rs386828909	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3511	3511	A	C	MI.11185	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	205	69	T	P	Acc/Ccc	-7,36	0	0	benign	0,02	neutral	0,31	neutral	2,74	neutral	-0,24	deleterious	-2,86	low_impact	1,3	neutral	0,86	neutral	0,64	deleterious	0,46	7,09	0,11	0,4	neutral	0,23	disease	0,64	disease	0,64	disease	0,7	4	neutral	0,68	deleterious	0,65	neutral	-6	neutral	0,19	medium_impact	0,84	medium_impact	0,08	medium_impact	-0,05	0,4	0,8	27,67	19,61	N	0,34	N	0,69	polymorphism	1	0,09	rs386828909	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3511	3511	A	G	MI.11186	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	205	69	T	A	Acc/Gcc	-7,36	0	0	benign	0,01	neutral	0,56	neutral	2,8	neutral	0,43	neutral	-1,3	low_impact	1,41	neutral	0,93	neutral	0,92	neutral	-0,43	0,33	0,25	0,45	neutral	0,17	neutral	0,11	neutral	0,49	neutral	0,33	3	neutral	0,42	deleterious	0,78	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,33	medium_impact	0,04	0,4	0,8	27,67	19,61	N	0,34	N	0,13	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3512	3512	C	A	MI.11187	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	206	69	T	N	aCc/aAc	-9,89	0	0	benign	0,26	neutral	0,39	neutral	2,73	neutral	-1,55	neutral	-2,34	low_impact	1,57	neutral	0,74	neutral	0,59	deleterious	0,71	8,87	0,27	0,45	neutral	0,38	neutral	0,4	neutral	0,49	neutral	0,46	1	neutral	0,53	deleterious	0,57	neutral	-6	neutral	0,24	medium_impact	-0,32	medium_impact	0,17	medium_impact	0,18	0,55	0,8	27,67	19,61	N	0,36	N	0,36	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3512	3512	C	T	MI.11188	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	206	69	T	I	aCc/aTc	-9,89	0	0	benign	0,01	neutral	0,4	neutral	2,83	neutral	0,65	neutral	-0,43	neutral_impact	-0,5	neutral	0,86	neutral	0,92	neutral	-0,34	0,53	0,16	0,45	neutral	0,14	neutral	0,13	neutral	0,34	neutral	0,26	5	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,18	low_impact	-1,63	0,73	0,85	27,67	19,61	N	0,31	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3512	3512	C	G	MI.11189	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	206	69	T	S	aCc/aGc	-9,89	0	0	benign	0,02	neutral	0,55	neutral	2,78	neutral	-0,19	neutral	-1,2	neutral_impact	0,58	neutral	0,84	neutral	0,98	deleterious	0,03	2,84	0,41	0,5	neutral	0,13	neutral	0,19	neutral	0,34	neutral	0,36	3	neutral	0,42	deleterious	0,77	neutral	-6	neutral	0,12	medium_impact	0,84	medium_impact	0,32	medium_impact	-0,68	0,66	0,8	27,67	19,61	N	0,33	N	0	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9052	9052	A	C	MI.1119	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	526	176	S	R	Agc/Cgc	-3,34	0	0	possibly_damaging	0,48	neutral	0,09	neutral	4,28	neutral	-1,35	neutral	-2,4	medium_impact	3,02	neutral	0,81	neutral	0,51	neutral	1,15	11,47	0,15	0,65	disease	0,52	disease	0,87	disease	0,64	disease	0,8	6	neutral	0,9	neutral	0,31	NA	0	deleterious	0,44	medium_impact	-0,72	medium_impact	-0,28	medium_impact	1,49	0,84	0,9	33,63	26,97	N	0,31	N	0,61	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3514	3514	C	G	MI.11190	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	208	70	L	V	Ctc/Gtc	-5,07	0	0	probably_damaging	1	neutral	0,52	neutral	2,68	neutral	-0,93	neutral	-2,5	medium_impact	2,4	neutral	0,7	damaging	0,22	deleterious	3,31	22,9	0,3	0,45	neutral	0,18	neutral	0,32	neutral	0,42	neutral	0,44	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,68	low_impact	-3,57	medium_impact	0,29	medium_impact	0,91	0,61	0,8	23,27	39,94	N	0,29	N	0,33	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3514	3514	C	T	MI.11191	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	208	70	L	F	Ctc/Ttc	-5,07	0	0	probably_damaging	1	neutral	0,72	neutral	2,54	neutral	-2,24	deleterious	-3,43	medium_impact	2,42	neutral	0,71	damaging	0,2	deleterious	3,84	23,4	0,24	0,45	neutral	0,42	disease	0,51	disease	0,55	disease	0,56	1	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,51	medium_impact	0,93	0,62	0,8	23,27	39,94	N	0,24	N	0,5	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3514	3514	C	A	MI.11192	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	208	70	L	I	Ctc/Atc	-5,07	0	0	probably_damaging	1	neutral	0,44	neutral	2,65	neutral	-1,41	neutral	-1,7	medium_impact	2,1	neutral	0,78	damaging	0,28	deleterious	3,97	23,6	0,28	0,45	neutral	0,22	neutral	0,22	neutral	0,38	neutral	0,35	3	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,68	low_impact	-3,57	medium_impact	0,22	medium_impact	0,65	0,56	0,8	23,27	39,94	N	0,32	N	0,4	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3515	3515	T	A	MI.11193	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	209	70	L	H	cTc/cAc	-0,01	0	0	probably_damaging	1	neutral	0,55	neutral	2,51	deleterious	-4,86	deleterious	-6,08	high_impact	4,4	neutral	0,75	damaging	0,18	deleterious	3,98	23,6	0,03	0,35	disease	0,64	disease	0,64	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,32	high_impact	2,65	0,34	0,8	23,27	39,94	N	0,37	N	0,87	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3515	3515	T	C	MI.11194	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	209	70	L	P	cTc/cCc	-0,01	0	0	probably_damaging	1	neutral	0,26	neutral	2,51	deleterious	-4,47	deleterious	-6,08	medium_impact	2,62	neutral	0,74	damaging	0,17	deleterious	3,77	23,4	0,02	0,35	disease	0,64	disease	0,65	disease	0,63	disease	0,51	0	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,81	low_impact	-3,57	medium_impact	0,02	medium_impact	1,1	0,34	0,8	23,27	39,94	N	0,26	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3515	3515	T	G	MI.11195	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	209	70	L	R	cTc/cGc	-0,01	0	0	probably_damaging	1	neutral	0,4	neutral	2,53	deleterious	-4,32	deleterious	-5,16	high_impact	4,4	neutral	0,74	damaging	0,16	deleterious	4,09	23,7	0,02	0,35	disease	0,55	disease	0,78	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,18	high_impact	2,65	0,24	0,8	23,27	39,94	N	0,48	N	0,94	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3517	3517	T	C	MI.11196	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	211	71	Y	H	Tac/Cac	-0,93	0,02	0	probably_damaging	0,98	neutral	0,54	neutral	2,46	deleterious	-3,41	deleterious	-3,74	medium_impact	2,67	neutral	0,7	damaging	0,23	deleterious	3,42	23	0,17	0,45	disease	0,64	disease	0,6	disease	0,8	disease	0,78	6	deleterious	0,98	neutral	0,28	deleterious	1	deleterious	0,79	low_impact	-2,34	medium_impact	0,31	medium_impact	1,14	0,27	0,8	24,21	37,73	N	0,27	N	0,79	polymorphism	0,99	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3517	3517	T	A	MI.11197	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	211	71	Y	N	Tac/Aac	-0,93	0,02	0	probably_damaging	0,98	neutral	0,32	neutral	2,44	deleterious	-4,42	deleterious	-5,67	medium_impact	2,67	neutral	0,71	neutral	0,3	deleterious	3,87	23,5	0,08	0,35	disease	0,78	disease	0,79	disease	0,74	disease	0,76	5	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,83	low_impact	-2,34	medium_impact	0,09	medium_impact	1,14	0,28	0,8	24,21	37,73	N	0,27	N	0,85	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3517	3517	T	G	MI.11198	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	211	71	Y	D	Tac/Gac	-0,93	0,02	0	probably_damaging	0,98	neutral	0,2	neutral	2,43	deleterious	-5,33	deleterious	-5,71	medium_impact	3,23	neutral	0,71	damaging	0,22	deleterious	3,79	23,4	0,04	0,35	disease	0,87	disease	0,83	disease	0,82	disease	0,86	7	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,86	low_impact	-2,34	medium_impact	-0,06	medium_impact	1,63	0,23	0,8	24,21	37,73	N	0,34	N	0,93	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3518	3518	A	C	MI.11199	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	212	71	Y	S	tAc/tCc	7,34	1	0	probably_damaging	0,98	neutral	0,43	neutral	2,45	deleterious	-4,01	deleterious	-4,78	low_impact	1,43	neutral	0,71	damaging	0,24	deleterious	3,59	23,2	0,06	0,35	disease	0,74	disease	0,71	disease	0,73	disease	0,76	5	neutral	0,98	neutral	0,23	neutral	-2	deleterious	0,8	low_impact	-2,34	medium_impact	0,21	medium_impact	0,06	0,29	0,8	24,21	37,73	N	0,53	P	0,86	polymorphism	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8578	8578	C	G	MI.112	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	52	18	P	A	Ccc/Gcc	-12,13	0	0	probably_damaging	1	neutral	0,05	neutral	4,64	neutral	0,93	deleterious	-6,67	medium_impact	2,99	neutral	0,78	neutral	0,55	deleterious	2,88	21,8	0,26	0,65	neutral	0,49	disease	0,63	disease	0,66	disease	0,6	2	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	-0,43	medium_impact	1,47	0,72	0,9	21,24	15,57	N	0,37	N	0,53	polymorphism	0,97	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9052	9052	A	G	MI.1120	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	526	176	S	G	Agc/Ggc	-3,34	0	0	benign	0,14	neutral	0,43	neutral	4,35	neutral	-0,44	neutral	-1,07	neutral_impact	0,12	neutral	0,84	neutral	0,97	deleterious	0,15	4,12	0,4	0,65	neutral	0,4	neutral	0,46	neutral	0,43	neutral	0,47	1	neutral	0,49	deleterious	0,65	neutral	-6	neutral	0,18	medium_impact	-0,01	medium_impact	0,22	medium_impact	-1	0,76	0,9	33,63	26,97	N	0,34	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3518	3518	A	G	MI.11200	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	212	71	Y	C	tAc/tGc	7,34	1	0	probably_damaging	0,99	neutral	0,18	neutral	2,43	deleterious	-5,59	deleterious	-4,77	medium_impact	3,23	neutral	0,68	damaging	0,19	deleterious	3,43	23	0,05	0,35	disease	0,88	disease	0,79	disease	0,77	disease	0,84	7	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,84	low_impact	-2,62	medium_impact	-0,09	medium_impact	1,63	0,19	0,8	24,21	37,73	P	0,64	P	0,84	polymorphism	0,95	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3518	3518	A	T	MI.11201	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	212	71	Y	F	tAc/tTc	7,34	1	0	benign	0,17	neutral	0,71	neutral	3,24	neutral	1,31	neutral	2,51	neutral_impact	-1,4	neutral	0,71	neutral	0,89	deleterious	0,67	8,63	0,31	0,45	neutral	0,15	neutral	0,08	neutral	0,43	neutral	0,22	6	neutral	0,17	deleterious	0,77	neutral	-6	neutral	0,19	medium_impact	-0,1	medium_impact	0,49	low_impact	-2,41	0,5	0,8	24,21	37,73	P	0,55	P	0,15	polymorphism	0,62	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3520	3520	A	T	MI.11202	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	214	72	I	F	Atc/Ttc	-1,85	0	0	benign	0,38	neutral	0,71	neutral	2,75	neutral	-1,28	neutral	-2,45	low_impact	1,62	neutral	0,71	neutral	0,41	deleterious	3,51	23,1	0,16	0,45	neutral	0,18	disease	0,53	neutral	0,33	neutral	0,43	1	neutral	0,29	deleterious	0,67	neutral	-6	neutral	0,29	medium_impact	-0,55	medium_impact	0,49	medium_impact	0,23	0,54	0,8	21,07	16,64	N	0,25	N	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3520	3520	A	G	MI.11203	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	214	72	I	V	Atc/Gtc	-1,85	0	0	benign	0,01	neutral	0,51	neutral	2,8	neutral	0,07	neutral	-0,65	low_impact	1,17	neutral	0,88	neutral	0,91	neutral	1,65	14,1	0,48	0,55	neutral	0,17	neutral	0,2	neutral	0,36	neutral	0,38	2	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,29	medium_impact	-0,17	0,43	0,8	21,07	16,64	N	0,39	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3520	3520	A	C	MI.11204	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	214	72	I	L	Atc/Ctc	-1,85	0	0	benign	0,01	neutral	0,66	neutral	2,85	neutral	0,18	neutral	-0,03	neutral_impact	0,4	neutral	0,84	neutral	0,71	neutral	1,12	11,31	0,23	0,45	neutral	0,14	neutral	0,16	neutral	0,27	neutral	0,26	5	neutral	0,32	deleterious	0,83	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	0,44	medium_impact	-0,84	0,58	0,8	21,07	16,64	N	0,32	N	0,59	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3521	3521	T	A	MI.11205	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	215	72	I	N	aTc/aAc	-0,01	0	0	possibly_damaging	0,47	neutral	0,31	neutral	2,72	neutral	-0,85	deleterious	-4,63	medium_impact	2,49	neutral	0,69	neutral	0,45	deleterious	4,34	24	0,15	0,4	neutral	0,3	disease	0,7	disease	0,51	disease	0,54	1	neutral	0,65	neutral	0,42	NA	0	deleterious	0,5	medium_impact	-0,7	medium_impact	0,08	medium_impact	0,99	0,21	0,8	21,07	16,64	N	0,36	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3521	3521	T	G	MI.11206	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	215	72	I	S	aTc/aGc	-0,01	0	0	benign	0,26	neutral	0,44	neutral	2,76	neutral	-1,04	deleterious	-3,66	medium_impact	2,76	neutral	0,85	neutral	0,58	deleterious	4,14	23,8	0,05	0,35	neutral	0,21	disease	0,66	disease	0,52	disease	0,59	2	neutral	0,47	deleterious	0,59	neutral	-3	neutral	0,27	medium_impact	-0,32	medium_impact	0,22	medium_impact	1,22	0,22	0,8	21,07	16,64	N	0,31	N	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3521	3521	T	C	MI.11207	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	215	72	I	T	aTc/aCc	-0,01	0	0	benign	0,01	neutral	0,41	neutral	2,8	neutral	-0,89	deleterious	-2,63	low_impact	1,17	neutral	0,87	neutral	0,94	deleterious	1,99	16,16	0,13	0,4	neutral	0,22	neutral	0,29	neutral	0,4	neutral	0,43	1	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,19	medium_impact	-0,17	0,41	0,8	21,07	16,64	N	0,41	N	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3522	3522	C	G	MI.11208	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	216	72	I	M	atC/atG	0,45	0	0	benign	0,03	neutral	0,22	neutral	2,72	neutral	-1,57	neutral	-0,88	low_impact	1,42	neutral	0,87	neutral	0,93	deleterious	2,05	16,55	0,35	0,5	neutral	0,36	neutral	0,32	neutral	0,36	neutral	0,46	1	neutral	0,77	deleterious	0,6	neutral	-6	neutral	0,14	medium_impact	0,67	medium_impact	-0,03	medium_impact	0,05	0,66	0,8	21,07	16,64	N	0,49	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3522	3522	C	A	MI.11209	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	216	72	I	M	atC/atA	0,45	0	0	benign	0,03	neutral	0,22	neutral	2,72	neutral	-1,57	neutral	-0,88	low_impact	1,42	neutral	0,87	neutral	0,93	deleterious	2,5	19,45	0,35	0,5	neutral	0,36	neutral	0,32	neutral	0,36	neutral	0,46	1	neutral	0,77	deleterious	0,6	neutral	-6	neutral	0,14	medium_impact	0,67	medium_impact	-0,03	medium_impact	0,05	0,66	0,8	21,07	16,64	N	0,49	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9052	9052	A	T	MI.1121	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	526	176	S	C	Agc/Tgc	-3,34	0	0	possibly_damaging	0,8	deleterious	0,01	neutral	4,22	deleterious	-4,68	deleterious	-3,02	medium_impact	2,12	neutral	0,73	neutral	0,4	deleterious	3,33	22,9	0,3	0,65	disease	0,84	disease	0,78	disease	0,55	disease	0,78	6	deleterious	0,99	neutral	0,11	deleterious	4	deleterious	0,64	low_impact	-1,33	medium_impact	-0,84	medium_impact	0,72	0,76	0,9	33,63	26,97	N	0,27	N	0,56	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3523	3523	A	C	MI.11210	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	217	73	T	P	Acc/Ccc	-6,44	0	0,01	possibly_damaging	0,55	neutral	0,21	neutral	2,75	neutral	-2,13	neutral	-1,89	low_impact	1,84	neutral	0,65	neutral	0,45	neutral	1,64	14,08	0,07	0,35	disease	0,53	disease	0,7	disease	0,66	disease	0,73	5	neutral	0,78	neutral	0,33	neutral	-3	deleterious	0,58	medium_impact	-0,83	medium_impact	-0,05	medium_impact	0,42	0,47	0,8	17,92	27,9	N	0,31	N	0,34	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3523	3523	A	G	MI.11211	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	217	73	T	A	Acc/Gcc	-6,44	0	0,01	benign	0,01	neutral	0,5	neutral	2,83	neutral	0,45	neutral	0,18	neutral_impact	-0,54	neutral	0,8	neutral	0,84	deleterious	-0,06	2,04	0,2	0,45	neutral	0,17	neutral	0,1	neutral	0,44	neutral	0,3	4	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,28	low_impact	-1,66	0,32	0,8	17,92	27,9	N	0,32	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3523	3523	A	T	MI.11212	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	217	73	T	S	Acc/Tcc	-6,44	0	0,01	benign	0,18	neutral	0,41	neutral	2,78	neutral	-0,67	neutral	-0,73	neutral_impact	0,08	neutral	0,72	neutral	0,72	neutral	1,28	12,18	0,35	0,5	neutral	0,3	neutral	0,25	neutral	0,41	neutral	0,44	1	neutral	0,51	deleterious	0,62	neutral	-6	neutral	0,19	medium_impact	-0,13	medium_impact	0,19	low_impact	-1,12	0,57	0,8	17,92	27,9	N	0,36	N	0,23	polymorphism	1	0,02	rs878982767	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3524	3524	C	A	MI.11213	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	218	73	T	N	aCc/aAc	-4,61	0	0	possibly_damaging	0,62	neutral	0,31	neutral	2,76	neutral	-1,76	neutral	-1,89	low_impact	1,29	neutral	0,7	neutral	0,65	deleterious	1,84	15,23	0,21	0,45	neutral	0,36	neutral	0,47	disease	0,53	disease	0,52	0	neutral	0,72	neutral	0,35	neutral	-3	deleterious	0,51	medium_impact	-0,95	medium_impact	0,08	medium_impact	-0,06	0,56	0,8	17,92	27,9	N	0,38	N	0,34	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3524	3524	C	T	MI.11214	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	218	73	T	I	aCc/aTc	-4,61	0	0	benign	0,01	neutral	0,4	neutral	3	neutral	1,99	neutral	2,38	neutral_impact	-1,68	neutral	0,77	neutral	0,93	neutral	-0,81	0,04	0,12	0,4	neutral	0,13	neutral	0,14	neutral	0,3	neutral	0,26	5	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,18	low_impact	-2,66	0,64	0,8	17,92	27,9	N	0,31	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3524	3524	C	G	MI.11215	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	218	73	T	S	aCc/aGc	-4,61	0	0	benign	0,18	neutral	0,41	neutral	2,78	neutral	-0,67	neutral	-0,73	neutral_impact	0,08	neutral	0,72	neutral	0,72	neutral	1,49	13,26	0,35	0,5	neutral	0,3	neutral	0,25	neutral	0,41	neutral	0,44	1	neutral	0,51	deleterious	0,62	neutral	-6	neutral	0,19	medium_impact	-0,13	medium_impact	0,19	low_impact	-1,12	0,57	0,8	17,92	27,9	N	0,37	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3526	3526	G	A	MI.11216	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	220	74	A	T	Gcc/Acc	-11,27	0	0	possibly_damaging	0,86	neutral	0,39	neutral	2,61	deleterious	-3,17	neutral	-0,22	low_impact	1,26	neutral	0,82	neutral	0,54	deleterious	0,44	6,96	0,13	0,4	neutral	0,28	neutral	0,24	neutral	0,44	neutral	0,43	1	neutral	0,86	neutral	0,27	neutral	-3	deleterious	0,58	low_impact	-1,49	medium_impact	0,17	medium_impact	-0,09	0,77	0,85	60,06	9,98	N	0,4	N	0,78	polymorphism	1	0,02	.	.	.	.	.	thyroid tumor	COSM1133243	.	.	.	.	.	.	.	.
chrM	3526	3526	G	C	MI.11217	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	220	74	A	P	Gcc/Ccc	-11,27	0	0	probably_damaging	0,96	neutral	0,21	neutral	2,52	deleterious	-4,59	deleterious	-2,85	high_impact	3,93	neutral	0,68	neutral	0,32	deleterious	2,12	16,97	0,04	0,35	disease	0,56	disease	0,89	disease	0,75	disease	0,82	6	neutral	0,98	neutral	0,13	deleterious	2	deleterious	0,82	low_impact	-2,05	medium_impact	-0,05	high_impact	2,24	0,55	0,8	60,06	9,98	N	0,42	N	0,95	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3526	3526	G	T	MI.11218	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	220	74	A	S	Gcc/Tcc	-11,27	0	0	benign	0,23	neutral	0,4	neutral	2,72	neutral	-2,77	neutral	-0,66	low_impact	0,9	neutral	0,82	neutral	0,56	deleterious	0,52	7,55	0,24	0,45	neutral	0,24	neutral	0,25	neutral	0,32	neutral	0,43	1	neutral	0,52	deleterious	0,59	neutral	-6	neutral	0,21	medium_impact	-0,26	medium_impact	0,18	medium_impact	-0,4	0,5	0,8	60,06	9,98	N	0,36	N	0,33	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3527	3527	C	T	MI.11219	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	221	74	A	V	gCc/gTc	0,68	0,26	0	possibly_damaging	0,9	neutral	0,5	neutral	2,61	neutral	-2,89	neutral	-2,1	medium_impact	2,89	neutral	0,72	neutral	0,51	deleterious	2,61	20,3	0,12	0,4	neutral	0,31	disease	0,7	disease	0,63	disease	0,71	4	neutral	0,89	neutral	0,3	NA	0	deleterious	0,67	low_impact	-1,65	medium_impact	0,28	medium_impact	1,34	0,61	0,8	60,06	9,98	N	0,4	N	0,71	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9053	9053	G	C	MI.1122	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	527	176	S	T	aGc/aCc	0,82	0	0,08	benign	0,01	neutral	0,91	neutral	4,36	neutral	-0,35	neutral	-0,41	neutral_impact	-0,59	neutral	0,82	neutral	0,82	neutral	-1,2	0,01	0,37	0,65	neutral	0,39	neutral	0,12	neutral	0,26	neutral	0,27	5	neutral	0,06	deleterious	0,95	neutral	-6	neutral	0,11	medium_impact	1,14	medium_impact	0,86	low_impact	-1,6	0,83	0,9	33,63	26,97	N	0,27	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3527	3527	C	A	MI.11220	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	221	74	A	D	gCc/gAc	0,68	0,26	0	probably_damaging	0,93	neutral	0,2	neutral	2,53	deleterious	-4,4	deleterious	-3,22	high_impact	4,28	neutral	0,76	neutral	0,39	deleterious	2,62	20,3	0,03	0,35	neutral	0,41	disease	0,88	disease	0,77	disease	0,8	6	neutral	0,96	neutral	0,14	deleterious	2	deleterious	0,76	low_impact	-1,81	medium_impact	-0,06	high_impact	2,55	0,31	0,8	60,06	9,98	N	0,54	P	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3527	3527	C	G	MI.11221	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	221	74	A	G	gCc/gGc	0,68	0,26	0	possibly_damaging	0,78	neutral	0,33	neutral	2,65	neutral	-2,19	deleterious	-2,63	medium_impact	2,27	neutral	0,78	neutral	0,55	deleterious	2,09	16,76	0,21	0,45	neutral	0,24	disease	0,73	disease	0,61	disease	0,7	4	neutral	0,81	neutral	0,28	NA	0	deleterious	0,6	low_impact	-1,27	medium_impact	0,1	medium_impact	0,79	0,69	0,85	60,06	9,98	N	0,32	N	0,66	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3529	3529	C	G	MI.11222	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	223	75	P	A	Ccg/Gcg	-5,52	0	0	probably_damaging	1	neutral	0,45	neutral	1,22	deleterious	-5,75	deleterious	-7,43	high_impact	4,12	damaging	0,59	damaging	0,07	deleterious	2,97	22,1	0,12	0,4	neutral	0,23	disease	0,5	disease	0,7	disease	0,65	3	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,69	low_impact	-3,57	medium_impact	0,23	high_impact	2,41	0,54	0,8	60,06	10,38	N	0,35	N	0,78	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3529	3529	C	T	MI.11223	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	223	75	P	S	Ccg/Tcg	-5,52	0	0	probably_damaging	1	neutral	0,52	neutral	1,21	deleterious	-6,02	deleterious	-7,43	high_impact	3,77	damaging	0,53	damaging	0,06	deleterious	3,79	23,4	0,09	0,35	neutral	0,39	disease	0,76	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,74	low_impact	-3,57	medium_impact	0,29	high_impact	2,1	0,14	0,8	60,06	10,38	N	0,32	N	0,74	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3529	3529	C	A	MI.11224	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	223	75	P	T	Ccg/Acg	-5,52	0	0	probably_damaging	1	neutral	0,33	neutral	1,19	deleterious	-6,45	deleterious	-7,43	high_impact	4,38	damaging	0,57	damaging	0,05	deleterious	3,59	23,2	0,11	0,4	neutral	0,34	disease	0,69	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,71	low_impact	-3,57	medium_impact	0,1	high_impact	2,64	0,4	0,8	60,06	10,38	N	0,35	N	0,91	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3530	3530	C	G	MI.11225	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	224	75	P	R	cCg/cGg	5,5	1	0	probably_damaging	1	neutral	0,28	neutral	1,18	deleterious	-6,98	deleterious	-8,36	high_impact	4,92	neutral	0,63	damaging	0,04	deleterious	3,49	23,1	0,04	0,35	disease	0,52	disease	0,86	disease	0,82	disease	0,79	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,05	high_impact	3,11	0,42	0,8	60,06	10,38	P	0,71	P	0,71	polymorphism	0,99	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3530	3530	C	A	MI.11226	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	224	75	P	Q	cCg/cAg	5,5	1	0	probably_damaging	1	neutral	0,24	neutral	1,18	deleterious	-7,25	deleterious	-7,43	high_impact	4,92	damaging	0,59	damaging	0,04	deleterious	3,96	23,6	0,09	0,4	disease	0,54	disease	0,82	disease	0,74	disease	0,75	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	-0,01	high_impact	3,11	0,37	0,8	60,06	10,38	P	0,68	P	0,84	polymorphism	0,99	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3530	3530	C	T	MI.11227	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	224	75	P	L	cCg/cTg	5,5	1	0	probably_damaging	1	neutral	0,9	neutral	1,19	deleterious	-6,82	deleterious	-9,29	high_impact	3,95	neutral	0,62	damaging	0,04	deleterious	4,31	24	0,08	0,35	neutral	0,18	disease	0,86	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,71	low_impact	-3,57	medium_impact	0,81	high_impact	2,26	0,7	0,85	60,06	10,38	N	0,49	N	1	polymorphism	0,99	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3532	3532	A	G	MI.11228	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	226	76	T	A	Acc/Gcc	-20	0	0	benign	0,01	neutral	0,37	neutral	2,82	neutral	0,7	neutral	-2,19	neutral_impact	0,76	neutral	0,9	neutral	0,86	deleterious	0,66	8,56	0,26	0,45	neutral	0,12	neutral	0,29	neutral	0,33	neutral	0,42	2	neutral	0,62	deleterious	0,68	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,15	medium_impact	-0,53	0,27	0,8	25,79	45,19	N	0,39	N	0,01	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3532	3532	A	T	MI.11229	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	226	76	T	S	Acc/Tcc	-20	0	0	benign	0,25	neutral	0,34	neutral	2,78	neutral	-0,12	neutral	-2,13	medium_impact	1,97	neutral	0,83	neutral	0,73	deleterious	0,73	9,05	0,39	0,5	neutral	0,24	neutral	0,49	disease	0,54	disease	0,65	3	neutral	0,59	deleterious	0,55	neutral	-3	neutral	0,21	medium_impact	-0,3	medium_impact	0,11	medium_impact	0,53	0,5	0,8	25,79	45,19	N	0,36	N	0,28	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9053	9053	G	T	MI.1123	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	527	176	S	I	aGc/aTc	0,82	0	0,08	benign	0,32	neutral	0,13	neutral	4,25	neutral	-2,16	deleterious	-3,37	low_impact	1,43	neutral	0,8	neutral	0,66	deleterious	2,32	18,3	0,29	0,65	neutral	0,47	disease	0,85	disease	0,57	disease	0,76	5	neutral	0,85	neutral	0,41	neutral	-6	neutral	0,33	medium_impact	-0,45	medium_impact	-0,18	medium_impact	0,13	0,84	0,9	33,63	26,97	N	0,31	N	0,66	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3532	3532	A	C	MI.11230	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	226	76	T	P	Acc/Ccc	-20	0	0	possibly_damaging	0,65	neutral	0,42	neutral	2,72	neutral	-2,12	deleterious	-3,48	medium_impact	2,94	neutral	0,64	neutral	0,36	deleterious	2,08	16,7	0,07	0,35	neutral	0,5	disease	0,86	disease	0,66	disease	0,77	5	neutral	0,66	neutral	0,39	NA	0	deleterious	0,61	low_impact	-1	medium_impact	0,2	medium_impact	1,38	0,32	0,8	25,79	45,19	N	0,31	N	0,76	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3533	3533	C	G	MI.11231	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	227	76	T	S	aCc/aGc	1,14	0	0	benign	0,25	neutral	0,34	neutral	2,78	neutral	-0,12	neutral	-2,13	medium_impact	1,97	neutral	0,83	neutral	0,73	deleterious	0,34	6,12	0,39	0,5	neutral	0,24	neutral	0,49	disease	0,54	disease	0,65	3	neutral	0,59	deleterious	0,55	neutral	-3	neutral	0,21	medium_impact	-0,3	medium_impact	0,11	medium_impact	0,53	0,5	0,8	25,79	45,19	N	0,35	N	0,28	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3533	3533	C	T	MI.11232	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	227	76	T	I	aCc/aTc	1,14	0	0	benign	0,02	neutral	0,56	neutral	2,85	neutral	1,54	neutral	-1,1	neutral_impact	0,12	neutral	0,83	neutral	0,93	deleterious	0,12	3,86	0,12	0,4	neutral	0,12	neutral	0,2	neutral	0,27	neutral	0,35	3	neutral	0,42	deleterious	0,77	neutral	-6	neutral	0,11	medium_impact	0,84	medium_impact	0,33	low_impact	-1,08	0,55	0,8	25,79	45,19	N	0,39	N	0,03	polymorphism	1	0,02	rs377091327	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3533	3533	C	A	MI.11233	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	227	76	T	N	aCc/aAc	1,14	0	0	possibly_damaging	0,65	neutral	0,23	neutral	2,73	neutral	-2,08	deleterious	-3,1	medium_impact	3,48	neutral	0,67	neutral	0,52	neutral	1,74	14,64	0,25	0,45	neutral	0,3	disease	0,71	disease	0,56	disease	0,7	4	neutral	0,79	neutral	0,29	NA	0	deleterious	0,52	low_impact	-1	medium_impact	-0,02	medium_impact	1,85	0,56	0,8	25,79	45,19	N	0,43	N	0,55	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3535	3535	T	A	MI.11234	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	229	77	L	M	Tta/Ata	-8,97	0	0,01	probably_damaging	1	neutral	0,29	neutral	2,37	neutral	-2,86	neutral	-0,72	neutral_impact	0,72	neutral	0,85	neutral	0,85	deleterious	2,18	17,38	0,24	0,45	neutral	0,39	neutral	0,12	neutral	0,28	neutral	0,29	4	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,67	low_impact	-3,57	medium_impact	0,06	medium_impact	-0,56	0,43	0,8	59,43	10,49	N	0,44	N	0,22	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3535	3535	T	G	MI.11235	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	229	77	L	V	Tta/Gta	-8,97	0	0,01	probably_damaging	1	neutral	0,38	neutral	2,45	neutral	-1,82	neutral	-2,15	medium_impact	2,1	neutral	0,7	neutral	0,52	deleterious	3,28	22,8	0,22	0,45	neutral	0,25	neutral	0,36	neutral	0,33	neutral	0,45	1	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,69	low_impact	-3,57	medium_impact	0,16	medium_impact	0,65	0,42	0,8	59,43	10,49	N	0,38	N	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3536	3536	T	G	MI.11236	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	230	77	L	W	tTa/tGa	-1,39	0	0	probably_damaging	1	neutral	0,15	neutral	2,29	deleterious	-6,16	deleterious	-4,78	high_impact	3,71	neutral	0,68	neutral	0,37	deleterious	3,64	23,2	0,06	0,35	disease	0,85	disease	0,7	disease	0,58	disease	0,74	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	-0,15	high_impact	2,05	0,19	0,8	59,43	10,49	N	0,38	N	0,92	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3536	3536	T	C	MI.11237	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	230	77	L	S	tTa/tCa	-1,39	0	0	probably_damaging	1	neutral	0,52	neutral	2,32	deleterious	-4,13	deleterious	-4,67	medium_impact	3,37	neutral	0,73	neutral	0,5	deleterious	3,63	23,2	0,06	0,35	disease	0,63	disease	0,57	disease	0,55	disease	0,62	2	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,29	medium_impact	1,76	0,27	0,8	59,43	10,49	N	0,31	N	0,91	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3537	3537	A	C	MI.11238	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	231	77	L	F	ttA/ttC	5,5	1	0,03	probably_damaging	1	neutral	0,84	neutral	2,39	neutral	-2,56	deleterious	-3,15	medium_impact	2,12	neutral	0,7	neutral	0,43	deleterious	3,38	22,9	0,2	0,45	neutral	0,33	neutral	0,31	neutral	0,31	neutral	0,46	1	deleterious	1	neutral	0,42	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,68	medium_impact	0,66	0,45	0,8	59,43	10,49	P	0,55	P	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3537	3537	A	T	MI.11239	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	231	77	L	F	ttA/ttT	5,5	1	0,03	probably_damaging	1	neutral	0,84	neutral	2,39	neutral	-2,56	deleterious	-3,15	medium_impact	2,12	neutral	0,7	neutral	0,43	deleterious	3,48	23,1	0,2	0,45	neutral	0,33	neutral	0,31	neutral	0,31	neutral	0,46	1	deleterious	1	neutral	0,42	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,68	medium_impact	0,66	0,45	0,8	59,43	10,49	P	0,55	P	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9053	9053	G	A	MI.1124	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	527	176	S	N	aGc/aAc	0,82	0	0,08	benign	0,22	neutral	0,8	neutral	4,33	neutral	-0,67	neutral	-0,69	low_impact	0,82	neutral	0,87	neutral	0,83	deleterious	0,59	8,11	0,63	0,7	neutral	0,44	neutral	0,48	neutral	0,36	neutral	0,48	0	neutral	0,12	deleterious	0,79	neutral	-6	neutral	0,31	medium_impact	-0,23	medium_impact	0,63	medium_impact	-0,4	0,72	0,9	33,63	26,97	N	0,22	N	0,03	polymorphism	1	0,01	rs199646902	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3538	3538	G	A	MI.11240	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	232	78	A	T	Gct/Act	0,45	0,99	0	probably_damaging	1	neutral	0,37	neutral	2,71	neutral	-1,29	deleterious	-3,5	medium_impact	2,08	neutral	0,67	damaging	0,1	deleterious	4,1	23,7	0,15	0,45	neutral	0,29	disease	0,57	neutral	0,35	neutral	0,45	1	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,15	medium_impact	0,63	0,57	0,8	14,78	29,75	N	0,43	N	0,55	polymorphism	1	0,1	.	.	.	.	.	.	COSM1155617	.	.	.	.	.	.	.	.
chrM	3538	3538	G	T	MI.11241	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	232	78	A	S	Gct/Tct	0,45	0,99	0	probably_damaging	1	neutral	0,49	neutral	2,78	neutral	-1,33	deleterious	-2,53	low_impact	1,66	neutral	0,81	neutral	0,67	deleterious	2,51	19,5	0,27	0,45	neutral	0,15	neutral	0,38	neutral	0,29	neutral	0,42	2	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,68	low_impact	-3,57	medium_impact	0,27	medium_impact	0,26	0,39	0,8	14,78	29,75	N	0,43	N	0,15	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3538	3538	G	C	MI.11242	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	232	78	A	P	Gct/Cct	0,45	0,99	0	probably_damaging	1	neutral	0,32	neutral	2,63	deleterious	-3,94	deleterious	-4,5	high_impact	3,88	neutral	0,71	damaging	0,06	deleterious	3,69	23,3	0,06	0,35	disease	0,56	disease	0,88	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,09	high_impact	2,2	0,54	0,8	14,78	29,75	N	0,49	N	0,99	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3539	3539	C	G	MI.11243	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	233	78	A	G	gCt/gGt	7,11	1	0	probably_damaging	1	neutral	0,38	neutral	2,65	neutral	-2,14	deleterious	-3,58	low_impact	1,81	neutral	0,74	damaging	0,17	deleterious	3,81	23,4	0,21	0,45	neutral	0,27	disease	0,69	neutral	0,35	neutral	0,5	0	deleterious	1	neutral	0,19	neutral	-2	deleterious	0,69	low_impact	-3,57	medium_impact	0,16	medium_impact	0,39	0,58	0,8	14,78	29,75	N	0,54	P	0,36	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3539	3539	C	A	MI.11244	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	233	78	A	D	gCt/gAt	7,11	1	0	probably_damaging	1	neutral	0,18	neutral	2,65	deleterious	-4,38	deleterious	-5,35	high_impact	3,68	neutral	0,77	damaging	0,06	deleterious	4,42	24,2	0,05	0,35	disease	0,51	disease	0,88	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	-0,09	high_impact	2,03	0,28	0,8	14,78	29,75	N	0,57	P	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3539	3539	C	T	MI.11245	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	233	78	A	V	gCt/gTt	7,11	1	0	probably_damaging	1	neutral	0,48	neutral	2,75	neutral	-0,68	deleterious	-3,65	medium_impact	2,68	neutral	0,67	damaging	0,07	deleterious	4,24	23,9	0,17	0,45	neutral	0,22	disease	0,72	disease	0,55	disease	0,64	3	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,26	medium_impact	1,15	0,58	0,8	14,78	29,75	P	0,55	P	0,75	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3541	3541	C	G	MI.11246	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	235	79	L	V	Ctc/Gtc	-6,67	0	0	possibly_damaging	0,74	neutral	0,54	neutral	2,48	neutral	-1,53	deleterious	-2,6	medium_impact	2,88	neutral	0,78	neutral	0,5	deleterious	3,32	22,9	0,24	0,45	neutral	0,21	neutral	0,38	disease	0,56	neutral	0,44	1	neutral	0,71	neutral	0,4	NA	0	deleterious	0,52	low_impact	-1,18	medium_impact	0,31	medium_impact	1,33	0,43	0,8	22,33	29,28	N	0,28	N	0,57	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3541	3541	C	T	MI.11247	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	235	79	L	F	Ctc/Ttc	-6,67	0	0	benign	0,08	neutral	0,99	neutral	2,49	neutral	-1,45	deleterious	-2,94	low_impact	1,03	neutral	0,79	neutral	0,75	deleterious	2,73	21	0,19	0,45	neutral	0,24	neutral	0,22	neutral	0,35	neutral	0,38	2	neutral	0,05	deleterious	0,96	neutral	-6	neutral	0,18	medium_impact	0,25	medium_impact	1,39	medium_impact	-0,29	0,32	0,8	22,33	29,28	N	0,25	N	0,26	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3541	3541	C	A	MI.11248	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	235	79	L	I	Ctc/Atc	-6,67	0	0	possibly_damaging	0,74	neutral	0,53	neutral	2,42	neutral	-2	neutral	-1,68	medium_impact	2,29	neutral	0,79	neutral	0,52	deleterious	3,96	23,6	0,24	0,45	neutral	0,27	neutral	0,4	neutral	0,46	neutral	0,42	2	neutral	0,71	neutral	0,4	NA	0	deleterious	0,56	low_impact	-1,18	medium_impact	0,3	medium_impact	0,81	0,33	0,8	22,33	29,28	N	0,3	N	0,55	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3542	3542	T	G	MI.11249	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	236	79	L	R	cTc/cGc	-0,47	0	0	probably_damaging	0,97	neutral	0,28	neutral	2,29	deleterious	-4,99	deleterious	-5,33	high_impact	4,49	neutral	0,67	neutral	0,3	deleterious	4,06	23,7	0,03	0,35	neutral	0,49	disease	0,79	disease	0,7	disease	0,7	4	neutral	0,97	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-2,17	medium_impact	0,05	high_impact	2,73	0,14	0,8	22,33	29,28	N	0,45	N	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9055	9055	G	C	MI.1125	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	529	177	A	P	Gcc/Ccc	-7,28	0	0,06	possibly_damaging	0,85	neutral	0,1	neutral	4,24	deleterious	-4,5	deleterious	-4,07	medium_impact	3,02	neutral	0,71	neutral	0,52	deleterious	3,93	23,5	0,1	0,65	disease	0,84	disease	0,91	disease	0,76	disease	0,82	6	neutral	0,95	neutral	0,13	NA	0	deleterious	0,82	low_impact	-1,47	medium_impact	-0,25	medium_impact	1,49	0,78	0,9	17,26	13,64	N	0,32	N	0,91	polymorphism	1	0,09	rs193303045	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3542	3542	T	A	MI.11250	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	236	79	L	H	cTc/cAc	-0,47	0	0	probably_damaging	0,98	neutral	0,44	neutral	2,28	deleterious	-5,63	deleterious	-6,02	high_impact	4,49	neutral	0,7	neutral	0,33	deleterious	3,94	23,5	0,06	0,35	disease	0,59	disease	0,66	disease	0,65	disease	0,66	3	deleterious	0,98	neutral	0,23	deleterious	2	deleterious	0,76	low_impact	-2,34	medium_impact	0,22	high_impact	2,73	0,25	0,8	22,33	29,28	N	0,42	N	0,88	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3542	3542	T	C	MI.11251	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	236	79	L	P	cTc/cCc	-0,47	0	0	probably_damaging	0,98	neutral	0,45	neutral	2,28	deleterious	-5,57	deleterious	-6,25	high_impact	4,14	neutral	0,68	neutral	0,34	deleterious	3,78	23,4	0,03	0,35	neutral	0,3	disease	0,72	disease	0,68	disease	0,67	3	deleterious	0,98	neutral	0,24	deleterious	2	deleterious	0,75	low_impact	-2,34	medium_impact	0,23	high_impact	2,43	0,28	0,8	22,33	29,28	N	0,34	N	0,93	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3544	3544	A	T	MI.11252	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	238	80	T	S	Acc/Tcc	-5,75	0	0	benign	0,01	neutral	0,62	neutral	2,73	neutral	-0,48	neutral	-1,97	low_impact	1,02	neutral	0,81	neutral	0,97	deleterious	0,06	3,14	0,42	0,55	neutral	0,15	neutral	0,36	neutral	0,27	neutral	0,44	1	neutral	0,36	deleterious	0,81	neutral	-6	neutral	0,13	medium_impact	1,12	medium_impact	0,39	medium_impact	-0,3	0,47	0,8	47,17	8,89	N	0,36	N	0,16	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3544	3544	A	G	MI.11253	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	238	80	T	A	Acc/Gcc	-5,75	0	0	benign	0,01	neutral	0,66	neutral	2,8	neutral	0,74	neutral	-2,41	low_impact	1,73	neutral	0,9	neutral	0,96	deleterious	0,31	5,84	0,27	0,45	neutral	0,16	neutral	0,32	neutral	0,26	neutral	0,44	1	neutral	0,32	deleterious	0,83	neutral	-6	neutral	0,13	medium_impact	1,12	medium_impact	0,44	medium_impact	0,32	0,33	0,8	47,17	8,89	N	0,37	N	0,24	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3544	3544	A	C	MI.11254	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	238	80	T	P	Acc/Ccc	-5,75	0	0	possibly_damaging	0,55	neutral	0,4	neutral	2,69	neutral	-2,69	deleterious	-3,83	high_impact	3,58	neutral	0,62	neutral	0,34	deleterious	2,97	22,1	0,06	0,35	disease	0,52	disease	0,84	disease	0,53	disease	0,71	4	neutral	0,6	neutral	0,43	deleterious	1	deleterious	0,6	medium_impact	-0,83	medium_impact	0,18	medium_impact	1,94	0,31	0,8	47,17	8,89	N	0,36	N	0,93	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3545	3545	C	G	MI.11255	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	239	80	T	S	aCc/aGc	-0,47	0	0	benign	0,01	neutral	0,62	neutral	2,73	neutral	-0,48	neutral	-1,97	low_impact	1,02	neutral	0,81	neutral	0,97	deleterious	0,26	5,25	0,42	0,55	neutral	0,15	neutral	0,36	neutral	0,27	neutral	0,44	1	neutral	0,36	deleterious	0,81	neutral	-6	neutral	0,13	medium_impact	1,12	medium_impact	0,39	medium_impact	-0,3	0,47	0,8	47,17	8,89	N	0,37	N	0,16	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3545	3545	C	T	MI.11256	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	239	80	T	I	aCc/aTc	-0,47	0	0	benign	0,02	neutral	0,58	neutral	2,89	neutral	0,5	deleterious	-2,67	neutral_impact	0,56	neutral	0,84	neutral	0,68	neutral	1	10,64	0,14	0,4	neutral	0,17	disease	0,52	neutral	0,29	neutral	0,42	2	neutral	0,39	deleterious	0,78	neutral	-6	neutral	0,15	medium_impact	0,84	medium_impact	0,35	medium_impact	-0,7	0,5	0,8	47,17	8,89	N	0,25	N	0,77	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3545	3545	C	A	MI.11257	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	239	80	T	N	aCc/aAc	-0,47	0	0	benign	0,26	neutral	0,3	neutral	2,7	neutral	-2,88	deleterious	-3,14	high_impact	3,58	neutral	0,67	neutral	0,48	deleterious	1,92	15,71	0,29	0,45	neutral	0,45	disease	0,72	neutral	0,39	disease	0,52	0	neutral	0,64	deleterious	0,52	neutral	-2	neutral	0,31	medium_impact	-0,32	medium_impact	0,07	medium_impact	1,94	0,59	0,8	47,17	8,89	N	0,46	N	0,51	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3547	3547	A	G	MI.11258	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	241	81	I	V	Atc/Gtc	-5,52	0	0	benign	0,04	neutral	0,54	neutral	2,86	neutral	-0,07	neutral	-0,92	low_impact	1,33	neutral	0,73	neutral	0,69	deleterious	2,89	21,8	0,4	0,5	neutral	0,14	neutral	0,2	neutral	0,45	neutral	0,34	3	neutral	0,42	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	0,55	medium_impact	0,31	medium_impact	-0,03	0,28	0,8	24,21	38,08	N	0,33	N	0,59	polymorphism	1	0,03	rs28358586	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3547	3547	A	C	MI.11259	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	241	81	I	L	Atc/Ctc	-5,52	0	0	benign	0,04	neutral	0,94	neutral	3,01	neutral	0,2	neutral	1,35	neutral_impact	-1,31	neutral	0,67	neutral	0,89	neutral	0,92	10,17	0,24	0,45	neutral	0,18	neutral	0,09	neutral	0,21	neutral	0,27	5	neutral	0,01	deleterious	0,95	neutral	-6	neutral	0,1	medium_impact	0,55	medium_impact	0,94	low_impact	-2,33	0,39	0,8	24,21	38,08	N	0,34	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9055	9055	G	T	MI.1126	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	529	177	A	S	Gcc/Tcc	-7,28	0	0,06	benign	0,05	neutral	0,32	neutral	4,28	neutral	-2,59	neutral	-2,16	medium_impact	2	neutral	0,72	neutral	0,61	deleterious	3,79	23,4	0,35	0,65	disease	0,64	disease	0,74	neutral	0,42	disease	0,54	1	neutral	0,65	deleterious	0,64	neutral	-3	neutral	0,28	medium_impact	0,46	medium_impact	0,11	medium_impact	0,62	0,88	0,9	17,26	13,64	N	0,3	N	0,19	polymorphism	1	0,02	rs193303045	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3547	3547	A	T	MI.11260	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	241	81	I	F	Atc/Ttc	-5,52	0	0	possibly_damaging	0,78	neutral	0,83	neutral	2,74	neutral	-1,4	neutral	-2,09	low_impact	1,69	neutral	0,7	neutral	0,51	deleterious	3,76	23,3	0,16	0,45	neutral	0,19	disease	0,56	neutral	0,48	disease	0,5	0	neutral	0,74	deleterious	0,53	neutral	-3	deleterious	0,56	low_impact	-1,27	medium_impact	0,66	medium_impact	0,29	0,37	0,8	24,21	38,08	N	0,31	N	0,6	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3548	3548	T	A	MI.11261	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	242	81	I	N	aTc/aAc	-1,16	0	0	possibly_damaging	0,87	neutral	0,29	neutral	2,73	deleterious	-3,14	deleterious	-4,87	medium_impact	2,38	neutral	0,68	neutral	0,51	deleterious	4,35	24,1	0,12	0,4	neutral	0,5	disease	0,73	disease	0,54	disease	0,69	4	neutral	0,9	neutral	0,21	NA	0	deleterious	0,67	low_impact	-1,53	medium_impact	0,06	medium_impact	0,89	0,19	0,8	24,21	38,08	N	0,35	N	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3548	3548	T	G	MI.11262	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	242	81	I	S	aTc/aGc	-1,16	0	0	possibly_damaging	0,69	neutral	0,55	neutral	2,8	neutral	-0,89	deleterious	-3,94	low_impact	1,52	neutral	0,69	neutral	0,53	deleterious	4,18	23,8	0,08	0,35	neutral	0,23	disease	0,58	disease	0,53	disease	0,6	2	neutral	0,65	neutral	0,43	neutral	-3	neutral	0,41	low_impact	-1,08	medium_impact	0,32	medium_impact	0,14	0,21	0,8	24,21	38,08	N	0,26	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3548	3548	T	C	MI.11263	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	242	81	I	T	aTc/aCc	-1,16	0	0	benign	0,06	neutral	0,52	neutral	2,77	neutral	-0,5	deleterious	-3	low_impact	1,64	neutral	0,64	neutral	0,69	deleterious	3,31	22,9	0,22	0,45	neutral	0,27	neutral	0,31	neutral	0,46	neutral	0,41	2	neutral	0,42	deleterious	0,73	neutral	-6	neutral	0,14	medium_impact	0,37	medium_impact	0,29	medium_impact	0,24	0,29	0,8	24,21	38,08	N	0,4	N	0,86	polymorphism	1	0,11	rs876661353	Uncertain significance	not_specified	RCV000223756.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	3549	3549	C	G	MI.11264	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	243	81	I	M	atC/atG	7,34	0,95	0,03	possibly_damaging	0,83	neutral	0,3	neutral	2,74	neutral	-1,74	neutral	-0,36	low_impact	1,4	neutral	0,71	neutral	0,61	deleterious	3,25	22,8	0,32	0,5	neutral	0,28	neutral	0,37	neutral	0,44	neutral	0,41	2	neutral	0,86	neutral	0,24	neutral	-3	deleterious	0,57	low_impact	-1,4	medium_impact	0,07	medium_impact	0,03	0,41	0,8	24,21	38,08	P	0,6	P	0,55	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3549	3549	C	A	MI.11265	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	243	81	I	M	atC/atA	7,34	0,95	0,03	possibly_damaging	0,83	neutral	0,3	neutral	2,74	neutral	-1,74	neutral	-0,36	low_impact	1,4	neutral	0,71	neutral	0,61	deleterious	3,74	23,3	0,32	0,5	neutral	0,28	neutral	0,37	neutral	0,44	neutral	0,41	2	neutral	0,86	neutral	0,24	neutral	-3	deleterious	0,57	low_impact	-1,4	medium_impact	0,07	medium_impact	0,03	0,41	0,8	24,21	38,08	P	0,6	P	0,55	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3550	3550	G	T	MI.11266	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	244	82	A	S	Gct/Tct	-4,61	0	0	benign	0,2	neutral	0,45	neutral	2,75	neutral	-1,91	neutral	-2,48	low_impact	1,64	neutral	0,82	damaging	0,2	deleterious	2,46	19,21	0,28	0,45	neutral	0,22	neutral	0,19	neutral	0,31	neutral	0,31	4	neutral	0,46	deleterious	0,63	neutral	-6	neutral	0,21	medium_impact	-0,19	medium_impact	0,23	medium_impact	0,24	0,33	0,8	54,72	9,4	N	0,33	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3550	3550	G	A	MI.11267	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	244	82	A	T	Gct/Act	-4,61	0	0	benign	0,12	neutral	0,31	neutral	2,68	neutral	-2,22	deleterious	-3,5	medium_impact	3,16	neutral	0,72	damaging	0,12	deleterious	4,08	23,7	0,19	0,45	neutral	0,24	disease	0,52	disease	0,57	disease	0,55	1	neutral	0,64	deleterious	0,6	neutral	-3	neutral	0,19	medium_impact	0,06	medium_impact	0,08	medium_impact	1,57	0,65	0,8	54,72	9,4	N	0,39	N	0,7	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3550	3550	G	C	MI.11268	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	244	82	A	P	Gct/Cct	-4,61	0	0	probably_damaging	0,96	neutral	0,4	neutral	2,62	deleterious	-3,42	deleterious	-4,49	medium_impact	2,98	neutral	0,71	damaging	0,07	deleterious	3,67	23,3	0,09	0,35	disease	0,57	disease	0,78	disease	0,71	disease	0,73	5	neutral	0,96	neutral	0,22	deleterious	1	deleterious	0,77	low_impact	-2,05	medium_impact	0,18	medium_impact	1,41	0,46	0,8	54,72	9,4	N	0,25	N	0,96	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3551	3551	C	T	MI.11269	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	245	82	A	V	gCt/gTt	5,04	1	0	possibly_damaging	0,83	neutral	0,45	neutral	2,78	neutral	-1,24	deleterious	-3,65	medium_impact	2,54	neutral	0,71	damaging	0,07	deleterious	4,32	24	0,18	0,45	neutral	0,16	disease	0,57	disease	0,52	neutral	0,49	0	neutral	0,83	neutral	0,31	NA	0	deleterious	0,56	low_impact	-1,4	medium_impact	0,23	medium_impact	1,03	0,51	0,8	54,72	9,4	P	0,58	P	0,72	polymorphism	0,99	0,13	.	.	.	.	.	.	.	.	.	C3551T	LHON (putative)	+	-	Reported	1
chrM	9055	9055	G	A	MI.1127	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	529	177	A	T	Gcc/Acc	-7,28	0	0,06	possibly_damaging	0,51	neutral	0,55	neutral	4,34	neutral	-2,28	deleterious	-2,61	low_impact	1,31	neutral	0,93	neutral	0,68	deleterious	3,12	22,6	0,39	0,65	disease	0,5	disease	0,61	neutral	0,41	neutral	0,45	1	neutral	0,47	deleterious	0,52	neutral	-3	deleterious	0,53	medium_impact	-0,77	medium_impact	0,34	medium_impact	0,03	0,7	0,9	17,26	13,64	N	0,2	N	0,34	polymorphism	1	0,06	rs193303045	.	.	.	.	.	.	.	1,93	G9055A	PD protective factor	+	-	Reported	2
chrM	3551	3551	C	G	MI.11270	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	245	82	A	G	gCt/gGt	5,04	1	0	possibly_damaging	0,74	neutral	0,18	neutral	2,64	deleterious	-3,47	deleterious	-3,56	medium_impact	3,16	neutral	0,77	damaging	0,11	deleterious	3,88	23,5	0,26	0,45	neutral	0,33	disease	0,55	disease	0,57	disease	0,62	2	neutral	0,87	neutral	0,22	NA	0	deleterious	0,55	low_impact	-1,18	medium_impact	-0,09	medium_impact	1,57	0,53	0,8	54,72	9,4	P	0,61	P	0,79	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3551	3551	C	A	MI.11271	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	245	82	A	D	gCt/gAt	5,04	1	0	possibly_damaging	0,89	neutral	0,11	neutral	2,64	deleterious	-4,87	deleterious	-5,31	high_impact	4,41	neutral	0,79	damaging	0,07	deleterious	4,32	24	0,06	0,35	disease	0,6	disease	0,8	disease	0,69	disease	0,69	4	neutral	0,96	neutral	0,11	deleterious	1	deleterious	0,72	low_impact	-1,6	medium_impact	-0,23	high_impact	2,66	0,28	0,8	54,72	9,4	P	0,6	P	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3553	3553	C	A	MI.11272	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	247	83	L	I	Ctt/Att	-6,9	0	0	probably_damaging	1	neutral	0,2	neutral	2,54	neutral	-1,88	neutral	-1,6	low_impact	1,9	neutral	0,89	neutral	0,6	deleterious	3,99	23,6	0,28	0,45	neutral	0,19	neutral	0,28	neutral	0,46	neutral	0,42	2	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,68	low_impact	-3,57	medium_impact	-0,06	medium_impact	0,47	0,3	0,8	56,92	9,14	N	0,48	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3553	3553	C	T	MI.11273	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	247	83	L	F	Ctt/Ttt	-6,9	0	0	probably_damaging	1	neutral	0,23	neutral	2,53	neutral	-1,36	deleterious	-3,27	medium_impact	2,31	neutral	0,88	neutral	0,32	deleterious	3,8	23,4	0,3	0,45	neutral	0,29	neutral	0,29	neutral	0,38	neutral	0,42	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,69	low_impact	-3,57	medium_impact	-0,02	medium_impact	0,83	0,36	0,8	56,92	9,14	N	0,41	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3553	3553	C	G	MI.11274	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	247	83	L	V	Ctt/Gtt	-6,9	0	0	probably_damaging	1	neutral	0,23	neutral	2,53	neutral	-1,54	neutral	-2,36	medium_impact	2,92	neutral	0,85	damaging	0,18	deleterious	3,34	22,9	0,29	0,45	neutral	0,2	neutral	0,3	disease	0,56	neutral	0,45	1	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,67	low_impact	-3,57	medium_impact	-0,02	medium_impact	1,36	0,36	0,8	56,92	9,14	N	0,37	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3554	3554	T	C	MI.11275	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	248	83	L	P	cTt/cCt	-1,85	0	0	probably_damaging	1	neutral	0,11	neutral	2,42	deleterious	-5,01	deleterious	-5,9	high_impact	4,47	neutral	0,61	damaging	0,08	deleterious	3,66	23,2	0,05	0,35	disease	0,62	disease	0,64	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	-0,23	high_impact	2,72	0,24	0,8	56,92	9,14	N	0,39	N	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3554	3554	T	G	MI.11276	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	248	83	L	R	cTt/cGt	-1,85	0	0	probably_damaging	1	deleterious	0,03	neutral	2,43	deleterious	-4,52	deleterious	-5,03	high_impact	4,47	neutral	0,66	damaging	0,1	deleterious	3,99	23,6	0,04	0,35	disease	0,52	disease	0,72	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-3,57	medium_impact	-0,57	high_impact	2,72	0,15	0,8	56,92	9,14	N	0,41	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3554	3554	T	A	MI.11277	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	248	83	L	H	cTt/cAt	-1,85	0	0	probably_damaging	1	neutral	0,09	neutral	2,42	deleterious	-5,05	deleterious	-5,91	high_impact	4,47	neutral	0,7	damaging	0,08	deleterious	3,95	23,6	0,07	0,35	disease	0,61	disease	0,59	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	-0,29	high_impact	2,72	0,21	0,8	56,92	9,14	N	0,41	N	0,97	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3556	3556	C	G	MI.11278	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	250	84	L	V	Cta/Gta	-4,38	0	0	benign	0,04	neutral	0,17	neutral	2,63	neutral	-1,26	neutral	-0,05	low_impact	1,56	neutral	0,83	neutral	0,45	deleterious	2,12	16,97	0,35	0,5	neutral	0,19	neutral	0,16	neutral	0,25	neutral	0,28	4	neutral	0,82	deleterious	0,57	neutral	-6	neutral	0,13	medium_impact	0,55	medium_impact	-0,11	medium_impact	0,17	0,38	0,8	30,19	51,37	N	0,51	P	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3556	3556	C	A	MI.11279	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	250	84	L	M	Cta/Ata	-4,38	0	0	probably_damaging	0,9	neutral	0,34	neutral	2,49	neutral	-2,39	neutral	0,4	neutral_impact	0,26	neutral	0,86	neutral	0,9	deleterious	1,97	16	0,22	0,45	neutral	0,31	neutral	0,08	neutral	0,24	neutral	0,27	5	neutral	0,91	neutral	0,22	neutral	-2	deleterious	0,6	low_impact	-1,65	medium_impact	0,11	medium_impact	-0,96	0,33	0,8	30,19	51,37	N	0,5	N	0,49	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9056	9056	C	G	MI.1128	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	530	177	A	G	gCc/gGc	2,67	0,99	0	benign	0,39	neutral	0,2	neutral	4,27	neutral	-2,48	deleterious	-3,33	low_impact	1,29	neutral	0,74	neutral	0,63	deleterious	2,94	22	0,22	0,65	disease	0,79	disease	0,72	neutral	0,41	disease	0,62	2	neutral	0,76	neutral	0,41	neutral	-6	deleterious	0,53	medium_impact	-0,57	medium_impact	-0,05	medium_impact	0,01	0,73	0,9	17,26	13,64	N	0,41	N	0,54	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3557	3557	T	A	MI.11280	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	251	84	L	Q	cTa/cAa	-0,01	0	0	probably_damaging	0,93	neutral	0,06	neutral	2,47	deleterious	-4,51	neutral	-1,28	high_impact	3,54	neutral	0,76	damaging	0,24	deleterious	3,8	23,4	0,06	0,35	disease	0,52	neutral	0,47	neutral	0,5	neutral	0,45	1	deleterious	0,98	neutral	0,07	deleterious	2	deleterious	0,68	low_impact	-1,81	medium_impact	-0,4	medium_impact	1,9	0,2	0,8	30,19	51,37	N	0,44	N	0,42	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3557	3557	T	G	MI.11281	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	251	84	L	R	cTa/cGa	-0,01	0	0	probably_damaging	0,9	neutral	0,07	neutral	2,47	deleterious	-4,34	neutral	-1,62	high_impact	3,54	neutral	0,73	damaging	0,2	deleterious	2,88	21,8	0,04	0,35	disease	0,5	disease	0,69	disease	0,63	disease	0,7	4	neutral	0,98	neutral	0,09	deleterious	2	deleterious	0,73	low_impact	-1,65	medium_impact	-0,35	medium_impact	1,9	0,16	0,8	30,19	51,37	N	0,39	N	0,51	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3557	3557	T	C	MI.11282	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	251	84	L	P	cTa/cCa	-0,01	0	0	probably_damaging	0,93	neutral	0,12	neutral	2,45	deleterious	-4,49	neutral	-1,92	high_impact	3,54	neutral	0,76	damaging	0,22	deleterious	3,67	23,3	0,04	0,35	disease	0,6	disease	0,71	disease	0,63	disease	0,7	4	neutral	0,97	neutral	0,1	deleterious	2	deleterious	0,75	low_impact	-1,81	medium_impact	-0,21	medium_impact	1,9	0,26	0,8	30,19	51,37	N	0,39	N	0,67	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3559	3559	C	A	MI.11283	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	253	85	L	M	Cta/Ata	-9,43	0	0	benign	0,15	neutral	0,29	neutral	2,71	neutral	-1,57	neutral	-0,16	neutral_impact	0,16	neutral	0,8	neutral	0,92	neutral	1,64	14,06	0,23	0,45	neutral	0,22	neutral	0,07	neutral	0,21	neutral	0,26	5	neutral	0,66	deleterious	0,57	neutral	-6	neutral	0,15	medium_impact	-0,04	medium_impact	0,06	low_impact	-1,05	0,54	0,8	30,82	39,41	N	0,51	P	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3559	3559	C	G	MI.11284	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	253	85	L	V	Cta/Gta	-9,43	0	0	possibly_damaging	0,53	neutral	0,18	neutral	2,78	neutral	-0,28	neutral	-1,05	low_impact	1,5	neutral	0,86	neutral	0,77	deleterious	3,25	22,8	0,28	0,45	neutral	0,16	neutral	0,18	neutral	0,28	neutral	0,33	3	neutral	0,81	neutral	0,33	neutral	-3	neutral	0,35	medium_impact	-0,8	medium_impact	-0,09	medium_impact	0,12	0,42	0,8	30,82	39,41	N	0,46	N	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3560	3560	T	G	MI.11285	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	254	85	L	R	cTa/cGa	-0,24	0	0	probably_damaging	0,93	deleterious	0,04	neutral	2,72	deleterious	-3,09	deleterious	-4,4	medium_impact	3,25	neutral	0,68	neutral	0,5	deleterious	4,04	23,7	0,06	0,35	neutral	0,49	disease	0,73	disease	0,64	disease	0,71	4	deleterious	0,99	neutral	0,06	deleterious	5	deleterious	0,73	low_impact	-1,81	medium_impact	-0,5	medium_impact	1,65	0,24	0,8	30,82	39,41	N	0,4	N	0,91	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3560	3560	T	A	MI.11286	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	254	85	L	Q	cTa/cAa	-0,24	0	0	probably_damaging	0,93	deleterious	0,04	neutral	2,72	deleterious	-3,2	deleterious	-4,12	medium_impact	3,25	neutral	0,71	neutral	0,56	deleterious	4,14	23,8	0,09	0,35	disease	0,51	disease	0,54	disease	0,51	disease	0,54	1	deleterious	0,99	neutral	0,06	deleterious	5	deleterious	0,68	low_impact	-1,81	medium_impact	-0,5	medium_impact	1,65	0,24	0,8	30,82	39,41	N	0,46	N	0,78	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3560	3560	T	C	MI.11287	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	254	85	L	P	cTa/cCa	-0,24	0	0	probably_damaging	0,95	deleterious	0,03	neutral	2,69	neutral	-2,14	deleterious	-5,03	medium_impact	3,25	damaging	0,6	neutral	0,43	deleterious	3,88	23,5	0,05	0,35	disease	0,6	disease	0,73	disease	0,66	disease	0,72	4	deleterious	0,99	neutral	0,04	deleterious	5	deleterious	0,76	low_impact	-1,95	medium_impact	-0,57	medium_impact	1,65	0,26	0,8	30,82	39,41	N	0,33	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3562	3562	T	G	MI.11288	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	256	86	W	G	Tga/Gga	-3,46	0	0	probably_damaging	1	neutral	0,08	neutral	2,45	deleterious	-4,45	deleterious	-12,07	high_impact	4,24	neutral	0,75	damaging	0,14	deleterious	3,78	23,4	0,08	0,35	neutral	0,45	disease	0,67	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,72	low_impact	-3,57	medium_impact	-0,32	high_impact	2,51	0,1	0,8	60,38	10,52	N	0,48	N	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3562	3562	T	C	MI.11289	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	256	86	W	R	Tga/Cga	-3,46	0	0	probably_damaging	1	neutral	0,06	neutral	2,47	deleterious	-3,16	deleterious	-12,99	high_impact	4,09	neutral	0,7	damaging	0,08	deleterious	3,47	23	0,06	0,35	disease	0,51	disease	0,83	disease	0,82	disease	0,77	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	-0,4	high_impact	2,38	0,08	0,8	60,38	10,52	N	0,47	N	0,98	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9056	9056	C	T	MI.1129	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	530	177	A	V	gCc/gTc	2,67	0,99	0	possibly_damaging	0,59	neutral	0,25	neutral	4,33	neutral	-1,51	deleterious	-3,19	medium_impact	2,29	damaging	0,59	neutral	0,48	deleterious	4,59	24,4	0,32	0,65	neutral	0,48	disease	0,83	disease	0,6	disease	0,7	4	neutral	0,76	neutral	0,33	NA	0	deleterious	0,63	medium_impact	-0,91	medium_impact	0,02	medium_impact	0,87	0,78	0,9	17,26	13,64	N	0,48	N	0,63	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3563	3563	G	C	MI.11290	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	257	86	W	S	tGa/tCa	5,73	1	0	probably_damaging	1	neutral	0,25	neutral	2,46	deleterious	-3,46	deleterious	-12,99	high_impact	3,55	neutral	0,69	damaging	0,14	deleterious	3,92	23,5	0,08	0,35	neutral	0,37	disease	0,78	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,74	low_impact	-3,57	medium_impact	0,01	medium_impact	1,91	0,11	0,8	60,38	10,52	P	0,53	P	0,99	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3563	3563	G	T	MI.11291	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	257	86	W	L	tGa/tTa	5,73	1	0	probably_damaging	1	neutral	1	neutral	2,52	neutral	-2,15	deleterious	-12,06	medium_impact	2,96	neutral	0,68	damaging	0,09	deleterious	4,12	23,8	0,1	0,4	neutral	0,19	disease	0,74	disease	0,73	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,7	low_impact	-3,57	high_impact	1,96	medium_impact	1,4	0,07	0,8	60,38	10,52	N	0,42	N	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3564	3564	A	C	MI.11292	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	258	86	W	C	tgA/tgC	8,95	1	0	probably_damaging	1	deleterious	0,04	neutral	2,44	deleterious	-5,1	deleterious	-12,06	high_impact	3,69	neutral	0,73	damaging	0,1	deleterious	3,88	23,5	0,08	0,35	neutral	0,47	disease	0,75	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-3,57	medium_impact	-0,5	high_impact	2,03	0,1	0,8	60,38	10,52	P	0,56	P	1	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3564	3564	A	T	MI.11293	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	258	86	W	C	tgA/tgT	8,95	1	0	probably_damaging	1	deleterious	0,04	neutral	2,44	deleterious	-5,1	deleterious	-12,06	high_impact	3,69	neutral	0,73	damaging	0,1	deleterious	3,97	23,6	0,08	0,35	neutral	0,47	disease	0,75	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-3,57	medium_impact	-0,5	high_impact	2,03	0,1	0,8	60,38	10,52	P	0,56	P	1	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3565	3565	A	G	MI.11294	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	259	87	T	A	Acc/Gcc	2,06	0,94	0	benign	0,01	neutral	0,26	neutral	2,87	neutral	1,46	neutral	-0,44	neutral_impact	-0,55	neutral	0,94	neutral	0,96	neutral	0,99	10,6	0,38	0,5	neutral	0,16	neutral	0,07	neutral	0,21	neutral	0,21	6	neutral	0,73	deleterious	0,63	neutral	-6	neutral	0,08	medium_impact	1,12	medium_impact	0,02	low_impact	-1,67	0,37	0,8	24,84	25,63	N	0,45	N	0,3	polymorphism	1	0,01	rs2854133	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3565	3565	A	C	MI.11295	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	259	87	T	P	Acc/Ccc	2,06	0,94	0	possibly_damaging	0,66	deleterious	0,03	neutral	2,73	neutral	-2,49	deleterious	-2,67	low_impact	1,38	neutral	0,64	neutral	0,39	deleterious	3,44	23	0,1	0,4	neutral	0,48	disease	0,71	disease	0,52	disease	0,6	2	neutral	0,97	neutral	0,19	deleterious	1	deleterious	0,51	low_impact	-1,02	medium_impact	-0,57	medium_impact	0,02	0,49	0,8	24,84	25,63	N	0,41	N	0,89	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3565	3565	A	T	MI.11296	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	259	87	T	S	Acc/Tcc	2,06	0,94	0	benign	0,03	neutral	0,3	neutral	2,8	neutral	-0,29	neutral	-1,17	neutral_impact	0,58	neutral	0,88	neutral	0,93	deleterious	1,99	16,13	0,43	0,55	neutral	0,27	neutral	0,21	neutral	0,22	neutral	0,37	3	neutral	0,68	deleterious	0,64	neutral	-6	neutral	0,13	medium_impact	0,67	medium_impact	0,07	medium_impact	-0,68	0,63	0,8	24,84	25,63	N	0,5	N	0,21	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3566	3566	C	A	MI.11297	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	260	87	T	N	aCc/aAc	-1,85	0	0	possibly_damaging	0,51	neutral	0,06	neutral	2,75	neutral	-2,59	deleterious	-2,63	medium_impact	2,11	neutral	0,67	neutral	0,55	deleterious	3,65	23,2	0,31	0,45	neutral	0,44	neutral	0,47	neutral	0,36	neutral	0,5	0	neutral	0,93	neutral	0,28	NA	0	neutral	0,33	medium_impact	-0,77	medium_impact	-0,4	medium_impact	0,65	0,57	0,8	24,84	25,63	N	0,44	N	0,76	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3566	3566	C	T	MI.11298	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	260	87	T	I	aCc/aTc	-1,85	0	0	benign	0,02	neutral	0,21	neutral	2,82	neutral	0,19	neutral	-0,59	neutral_impact	0,23	neutral	0,82	neutral	0,94	neutral	1,09	11,17	0,18	0,45	neutral	0,21	neutral	0,26	neutral	0,25	neutral	0,43	1	neutral	0,78	deleterious	0,6	neutral	-6	neutral	0,12	medium_impact	0,84	medium_impact	-0,05	medium_impact	-0,99	0,58	0,8	24,84	25,63	N	0,42	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3566	3566	C	G	MI.11299	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	260	87	T	S	aCc/aGc	-1,85	0	0	benign	0,03	neutral	0,3	neutral	2,8	neutral	-0,29	neutral	-1,17	neutral_impact	0,58	neutral	0,88	neutral	0,93	deleterious	2,11	16,91	0,43	0,55	neutral	0,27	neutral	0,21	neutral	0,22	neutral	0,37	3	neutral	0,68	deleterious	0,64	neutral	-6	neutral	0,13	medium_impact	0,67	medium_impact	0,07	medium_impact	-0,68	0,63	0,8	24,84	25,63	N	0,49	N	0,21	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8578	8578	C	T	MI.113	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	52	18	P	S	Ccc/Tcc	-12,13	0	0	probably_damaging	1	neutral	0,84	neutral	4,67	neutral	0,93	deleterious	-6,59	low_impact	1,46	neutral	0,83	neutral	0,65	deleterious	3,6	23,2	0,47	0,65	neutral	0,46	disease	0,66	neutral	0,42	neutral	0,46	1	deleterious	1	neutral	0,42	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,7	medium_impact	0,15	0,41	0,9	21,24	15,57	N	0,24	N	0,49	polymorphism	0,95	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9056	9056	C	A	MI.1130	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	530	177	A	D	gCc/gAc	2,67	0,99	0	possibly_damaging	0,64	neutral	0,1	neutral	4,24	deleterious	-3,98	deleterious	-4,76	high_impact	3,58	neutral	0,71	neutral	0,46	deleterious	4,61	24,4	0,09	0,65	disease	0,88	disease	0,93	disease	0,75	disease	0,85	7	neutral	0,91	neutral	0,23	deleterious	1	deleterious	0,73	medium_impact	-0,99	medium_impact	-0,25	medium_impact	1,97	0,66	0,9	17,26	13,64	N	0,48	N	0,95	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3568	3568	C	T	MI.11300	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	262	88	P	S	Ccc/Tcc	-7,36	0	0	probably_damaging	1	neutral	0,39	neutral	2,8	neutral	-1,68	deleterious	-7,39	medium_impact	2,38	neutral	0,8	damaging	0,13	deleterious	3,83	23,4	0,3	0,45	neutral	0,39	disease	0,57	neutral	0,33	neutral	0,47	1	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,17	medium_impact	0,89	0,21	0,8	59,43	10,54	N	0,26	N	0,74	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3568	3568	C	A	MI.11301	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	262	88	P	T	Ccc/Acc	-7,36	0	0	probably_damaging	1	neutral	0,3	neutral	2,83	neutral	-1,3	deleterious	-7,4	medium_impact	2,37	neutral	0,67	damaging	0,1	deleterious	3,62	23,2	0,22	0,45	neutral	0,35	disease	0,59	neutral	0,41	neutral	0,48	0	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,07	medium_impact	0,88	0,51	0,8	59,43	10,54	N	0,29	N	0,91	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3568	3568	C	G	MI.11302	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	262	88	P	A	Ccc/Gcc	-7,36	0	0	probably_damaging	1	neutral	0,66	neutral	2,83	neutral	-0,44	deleterious	-7,4	medium_impact	2,38	neutral	0,72	damaging	0,13	deleterious	3,01	22,3	0,24	0,45	neutral	0,32	neutral	0,45	neutral	0,44	neutral	0,46	1	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,69	low_impact	-3,57	medium_impact	0,44	medium_impact	0,89	0,58	0,8	59,43	10,54	N	0,24	N	0,78	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3569	3569	C	G	MI.11303	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	263	88	P	R	cCc/cGc	5,5	1	0	probably_damaging	1	neutral	0,23	neutral	2,77	neutral	-2,89	deleterious	-8,33	high_impact	3,91	neutral	0,77	damaging	0,1	deleterious	3,56	23,1	0,13	0,4	neutral	0,49	disease	0,79	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	-0,02	high_impact	2,23	0,39	0,8	59,43	10,54	P	0,59	P	0,71	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3569	3569	C	A	MI.11304	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	263	88	P	H	cCc/cAc	5,5	1	0	probably_damaging	1	neutral	0,36	neutral	2,75	deleterious	-3,48	deleterious	-8,33	high_impact	3,91	neutral	0,7	damaging	0,1	deleterious	3,93	23,5	0,13	0,4	disease	0,63	disease	0,74	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	0,14	high_impact	2,23	0,34	0,8	59,43	10,54	P	0,63	P	0,69	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3569	3569	C	T	MI.11305	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	263	88	P	L	cCc/cTc	5,5	1	0	probably_damaging	1	neutral	1	neutral	2,89	neutral	-0,14	deleterious	-9,25	low_impact	1,44	neutral	0,7	damaging	0,08	deleterious	4,32	24	0,22	0,45	neutral	0,33	disease	0,62	neutral	0,31	neutral	0,44	1	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,7	low_impact	-3,57	high_impact	1,96	medium_impact	0,07	0,63	0,8	59,43	10,54	N	0,4	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3571	3571	C	A	MI.11306	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	265	89	L	I	Ctc/Atc	-9,43	0	0,01	benign	0,17	neutral	0,44	neutral	2,67	neutral	-0,6	neutral	-1,23	neutral_impact	0,7	neutral	0,88	neutral	0,83	deleterious	2,71	20,9	0,33	0,5	neutral	0,29	neutral	0,11	neutral	0,13	neutral	0,29	4	neutral	0,47	deleterious	0,64	neutral	-6	neutral	0,2	medium_impact	-0,1	medium_impact	0,22	medium_impact	-0,58	0,4	0,8	33,02	10,16	N	0,5	N	0,07	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3571	3571	C	G	MI.11307	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	265	89	L	V	Ctc/Gtc	-9,43	0	0,01	benign	0,17	neutral	0,33	neutral	2,64	neutral	-0,74	neutral	-1,85	low_impact	1,86	neutral	0,88	neutral	0,59	deleterious	3,26	22,8	0,32	0,5	neutral	0,19	neutral	0,28	neutral	0,21	neutral	0,44	1	neutral	0,61	deleterious	0,58	neutral	-6	neutral	0,18	medium_impact	-0,1	medium_impact	0,1	medium_impact	0,44	0,52	0,8	33,02	10,16	N	0,47	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3571	3571	C	T	MI.11308	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	265	89	L	F	Ctc/Ttc	-9,43	0	0,01	probably_damaging	0,96	neutral	0,54	neutral	2,43	neutral	-2,83	deleterious	-2,87	low_impact	1,14	neutral	0,82	neutral	0,52	deleterious	3,83	23,4	0,3	0,45	neutral	0,2	neutral	0,33	neutral	0,21	neutral	0,45	1	neutral	0,95	neutral	0,29	neutral	-2	deleterious	0,67	low_impact	-2,05	medium_impact	0,31	medium_impact	-0,19	0,48	0,8	33,02	10,16	N	0,23	N	0,86	polymorphism	1	0,09	rs200453691	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3572	3572	T	A	MI.11309	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	266	89	L	H	cTc/cAc	-2,54	0	0	probably_damaging	0,99	neutral	0,28	neutral	2,36	deleterious	-5,54	deleterious	-5,4	high_impact	3,87	neutral	0,71	neutral	0,32	deleterious	4,01	23,6	0,06	0,35	disease	0,67	disease	0,66	disease	0,62	disease	0,7	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,77	low_impact	-2,62	medium_impact	0,05	high_impact	2,19	0,14	0,8	33,02	10,16	N	0,35	N	0,86	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9058	9058	A	G	MI.1131	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	532	178	T	A	Acc/Gcc	-10,75	0	0	benign	0,02	neutral	0,73	neutral	4,44	neutral	-0,96	neutral	-1,97	neutral_impact	-0,14	neutral	0,97	neutral	0,87	deleterious	1,97	15,99	0,49	0,65	neutral	0,28	neutral	0,17	neutral	0,35	neutral	0,27	5	neutral	0,23	deleterious	0,86	neutral	-6	neutral	0,08	medium_impact	0,85	medium_impact	0,54	low_impact	-1,22	0,54	0,9	22,57	14,83	N	0,35	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	2,07	A9058G	Possibly LVNC cardiomyopathy-associated	+	-	Reported	1
chrM	3572	3572	T	C	MI.11310	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	266	89	L	P	cTc/cCc	-2,54	0	0	probably_damaging	0,98	neutral	0,27	neutral	2,37	deleterious	-5,36	deleterious	-5,43	high_impact	3,87	neutral	0,75	neutral	0,35	deleterious	3,79	23,4	0,05	0,35	disease	0,68	disease	0,79	disease	0,52	disease	0,68	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-2,34	medium_impact	0,03	high_impact	2,19	0,15	0,8	33,02	10,16	N	0,36	N	0,92	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3572	3572	T	G	MI.11311	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	266	89	L	R	cTc/cGc	-2,54	0	0	probably_damaging	0,97	neutral	0,15	neutral	2,37	deleterious	-4,83	deleterious	-4,59	high_impact	3,87	neutral	0,67	neutral	0,3	deleterious	4,1	23,7	0,04	0,35	disease	0,59	disease	0,79	disease	0,66	disease	0,73	5	deleterious	0,98	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-2,17	medium_impact	-0,15	high_impact	2,19	0,1	0,8	33,02	10,16	N	0,37	N	0,97	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3574	3574	C	T	MI.11312	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	268	90	P	S	Ccc/Tcc	-6,21	0	0	probably_damaging	1	neutral	0,36	neutral	1,3	deleterious	-5,81	deleterious	-7,27	medium_impact	3,28	neutral	0,79	damaging	0,13	deleterious	3,75	23,3	0,13	0,4	neutral	0,22	disease	0,72	disease	0,63	disease	0,61	2	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,14	medium_impact	1,68	0,16	0,8	60,38	10,17	N	0,27	N	0,74	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3574	3574	C	G	MI.11313	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	268	90	P	A	Ccc/Gcc	-6,21	0	0	probably_damaging	1	neutral	0,38	neutral	1,31	deleterious	-5,54	deleterious	-7,29	high_impact	4,17	neutral	0,75	damaging	0,14	deleterious	2,99	22,2	0,13	0,4	neutral	0,21	disease	0,59	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,69	low_impact	-3,57	medium_impact	0,16	high_impact	2,45	0,47	0,8	60,38	10,17	N	0,36	N	0,78	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3574	3574	C	A	MI.11314	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	268	90	P	T	Ccc/Acc	-6,21	0	0	probably_damaging	1	neutral	0,43	neutral	1,28	deleterious	-6,24	deleterious	-7,26	medium_impact	3,42	neutral	0,7	damaging	0,12	deleterious	3,58	23,2	0,13	0,4	neutral	0,23	disease	0,74	disease	0,6	disease	0,61	2	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,21	medium_impact	1,8	0,44	0,8	60,38	10,17	N	0,26	N	0,91	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3575	3575	C	T	MI.11315	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	269	90	P	L	cCc/cTc	5,27	1	0	probably_damaging	1	neutral	1	neutral	1,28	deleterious	-6,59	deleterious	-9,14	high_impact	3,52	neutral	0,74	damaging	0,08	deleterious	4,31	24	0,1	0,4	neutral	0,25	disease	0,81	disease	0,7	disease	0,71	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,72	low_impact	-3,57	high_impact	1,96	medium_impact	1,89	0,46	0,8	60,38	10,17	N	0,41	N	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3575	3575	C	A	MI.11316	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	269	90	P	H	cCc/cAc	5,27	1	0	probably_damaging	1	neutral	0,29	neutral	1,26	deleterious	-7,86	deleterious	-8,24	high_impact	4,53	neutral	0,74	damaging	0,1	deleterious	3,94	23,5	0,09	0,35	neutral	0,42	disease	0,82	disease	0,79	disease	0,77	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	0,06	high_impact	2,77	0,25	0,8	60,38	10,17	P	0,6	P	0,69	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3575	3575	C	G	MI.11317	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	269	90	P	R	cCc/cGc	5,27	1	0	probably_damaging	1	neutral	0,19	neutral	1,27	deleterious	-6,76	deleterious	-8,23	high_impact	4,87	neutral	0,78	damaging	0,1	deleterious	3,49	23,1	0,06	0,35	neutral	0,28	disease	0,84	disease	0,81	disease	0,76	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	-0,08	high_impact	3,06	0,36	0,8	60,38	10,17	P	0,64	P	0,71	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3577	3577	A	C	MI.11318	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	271	91	M	L	Ata/Cta	-8,97	0	0	benign	0,01	neutral	1	neutral	2,94	neutral	1,34	neutral	-1,25	neutral_impact	0,42	neutral	0,9	neutral	0,82	neutral	1,43	12,94	0,28	0,45	neutral	0,13	neutral	0,34	neutral	0,31	neutral	0,44	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,11	medium_impact	1,12	high_impact	1,96	medium_impact	-0,82	0,27	0,8	52,52	9,42	N	0,34	N	0,95	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3577	3577	A	T	MI.11319	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	271	91	M	L	Ata/Tta	-8,97	0	0	benign	0,01	neutral	1	neutral	2,94	neutral	1,34	neutral	-1,25	neutral_impact	0,42	neutral	0,9	neutral	0,82	neutral	1,57	13,67	0,28	0,45	neutral	0,13	neutral	0,34	neutral	0,31	neutral	0,44	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,11	medium_impact	1,12	high_impact	1,96	medium_impact	-0,82	0,27	0,8	52,52	9,42	N	0,34	N	0,95	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9058	9058	A	T	MI.1132	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	532	178	T	S	Acc/Tcc	-10,75	0	0	benign	0,28	neutral	0,66	neutral	4,33	neutral	-1,8	neutral	-2,23	low_impact	0,9	neutral	0,81	neutral	0,59	deleterious	3,85	23,4	0,42	0,65	neutral	0,48	neutral	0,39	neutral	0,36	neutral	0,42	2	neutral	0,25	deleterious	0,69	neutral	-6	neutral	0,38	medium_impact	-0,37	medium_impact	0,45	medium_impact	-0,33	0,74	0,9	22,57	14,83	N	0,25	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3577	3577	A	G	MI.11320	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	271	91	M	V	Ata/Gta	-8,97	0	0	benign	0,08	neutral	0,45	neutral	2,88	neutral	1,03	neutral	-2,38	low_impact	1,7	neutral	0,8	damaging	0,12	deleterious	2,61	20,2	0,23	0,45	neutral	0,15	disease	0,52	neutral	0,38	neutral	0,46	1	neutral	0,49	deleterious	0,69	neutral	-6	neutral	0,15	medium_impact	0,25	medium_impact	0,23	medium_impact	0,3	0,26	0,8	52,52	9,42	N	0,25	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3578	3578	T	A	MI.11321	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	272	91	M	K	aTa/aAa	1,37	0,77	0	possibly_damaging	0,61	neutral	0,16	neutral	2,72	neutral	-1,85	deleterious	-4,71	medium_impact	3,06	neutral	0,62	damaging	0,08	deleterious	3,88	23,5	0,05	0,35	neutral	0,22	disease	0,81	disease	0,75	disease	0,76	5	neutral	0,85	neutral	0,28	NA	0	deleterious	0,57	medium_impact	-0,93	medium_impact	-0,13	medium_impact	1,48	0,11	0,8	52,52	9,42	N	0,38	N	1	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3578	3578	T	C	MI.11322	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	272	91	M	T	aTa/aCa	1,37	0,77	0	benign	0,41	neutral	0,4	neutral	2,76	neutral	-0,25	deleterious	-4,1	medium_impact	2,51	neutral	0,82	damaging	0,14	deleterious	2,84	21,6	0,17	0,45	neutral	0,17	disease	0,65	disease	0,58	neutral	0,49	0	neutral	0,54	deleterious	0,5	neutral	-3	deleterious	0,46	medium_impact	-0,6	medium_impact	0,18	medium_impact	1	0,09	0,8	52,52	9,42	N	0,25	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3579	3579	A	C	MI.11323	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	273	91	M	I	atA/atC	5,73	0,97	0	benign	0,02	neutral	0,43	neutral	2,82	neutral	0,82	neutral	-2,12	medium_impact	2,11	neutral	0,85	neutral	0,29	deleterious	2,17	17,32	0,24	0,45	neutral	0,13	disease	0,53	neutral	0,31	neutral	0,45	1	neutral	0,55	deleterious	0,71	neutral	-3	neutral	0,14	medium_impact	0,84	medium_impact	0,21	medium_impact	0,65	0,31	0,8	52,52	9,42	N	0,52	P	0,95	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3579	3579	A	T	MI.11324	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	273	91	M	I	atA/atT	5,73	0,97	0	benign	0,02	neutral	0,43	neutral	2,82	neutral	0,82	neutral	-2,12	medium_impact	2,11	neutral	0,85	neutral	0,29	deleterious	2,26	17,9	0,24	0,45	neutral	0,13	disease	0,53	neutral	0,31	neutral	0,45	1	neutral	0,55	deleterious	0,71	neutral	-3	neutral	0,14	medium_impact	0,84	medium_impact	0,21	medium_impact	0,65	0,31	0,8	52,52	9,42	P	0,52	P	0,95	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3580	3580	C	A	MI.11325	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	274	92	P	T	Ccc/Acc	-3,23	0	0	probably_damaging	1	neutral	0,39	neutral	2,82	neutral	-1,16	deleterious	-7,4	medium_impact	2,29	neutral	0,65	damaging	0,13	deleterious	3,62	23,2	0,22	0,45	neutral	0,17	disease	0,62	neutral	0,4	neutral	0,47	1	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,67	low_impact	-3,57	medium_impact	0,17	medium_impact	0,81	0,4	0,8	58,81	10,66	N	0,27	N	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3580	3580	C	G	MI.11326	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	274	92	P	A	Ccc/Gcc	-3,23	0	0	probably_damaging	1	neutral	0,51	neutral	2,85	neutral	-0,64	deleterious	-7,41	medium_impact	2,31	neutral	0,69	damaging	0,17	deleterious	3,04	22,3	0,22	0,45	neutral	0,15	disease	0,51	neutral	0,4	neutral	0,48	0	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,67	low_impact	-3,57	medium_impact	0,29	medium_impact	0,83	0,47	0,8	58,81	10,66	N	0,26	N	0,78	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3580	3580	C	T	MI.11327	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	274	92	P	S	Ccc/Tcc	-3,23	0	0	probably_damaging	1	neutral	0,4	neutral	2,86	neutral	-0,88	deleterious	-7,4	medium_impact	1,99	neutral	0,71	damaging	0,17	deleterious	3,83	23,4	0,24	0,45	neutral	0,14	disease	0,57	neutral	0,24	neutral	0,42	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,67	low_impact	-3,57	medium_impact	0,18	medium_impact	0,55	0,12	0,8	58,81	10,66	N	0,29	N	0,74	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3581	3581	C	A	MI.11328	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	275	92	P	H	cCc/cAc	5,5	1	0	probably_damaging	1	neutral	0,54	neutral	2,78	neutral	-2,87	deleterious	-8,34	medium_impact	2,88	neutral	0,68	damaging	0,13	deleterious	4,05	23,7	0,13	0,4	neutral	0,29	disease	0,76	neutral	0,4	disease	0,56	1	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,31	medium_impact	1,33	0,25	0,8	58,81	10,66	N	0,42	N	0,69	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3581	3581	C	G	MI.11329	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	275	92	P	R	cCc/cGc	5,5	1	0	probably_damaging	1	neutral	0,35	neutral	2,82	neutral	-1,68	deleterious	-8,34	high_impact	3,92	neutral	0,73	damaging	0,14	deleterious	3,52	23,1	0,13	0,4	neutral	0,17	disease	0,79	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,7	low_impact	-3,57	medium_impact	0,12	high_impact	2,24	0,3	0,8	58,81	10,66	P	0,56	P	0,71	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9058	9058	A	C	MI.1133	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	532	178	T	P	Acc/Ccc	-10,75	0	0	possibly_damaging	0,68	neutral	0,16	neutral	4,29	deleterious	-3,29	deleterious	-3,85	medium_impact	2,56	neutral	0,86	neutral	0,44	deleterious	3,99	23,6	0,13	0,65	disease	0,79	disease	0,84	disease	0,73	disease	0,81	6	neutral	0,86	neutral	0,24	NA	0	deleterious	0,75	low_impact	-1,07	medium_impact	-0,12	medium_impact	1,1	0,61	0,9	22,57	14,83	N	0,31	N	0,93	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3581	3581	C	T	MI.11330	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	275	92	P	L	cCc/cTc	5,5	1	0	probably_damaging	1	neutral	0,65	neutral	2,82	neutral	-1,85	deleterious	-9,26	medium_impact	2,12	neutral	0,77	damaging	0,13	deleterious	4,26	23,9	0,16	0,45	neutral	0,27	disease	0,69	neutral	0,41	neutral	0,49	0	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,69	low_impact	-3,57	medium_impact	0,43	medium_impact	0,66	0,56	0,8	58,81	10,66	N	0,42	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3583	3583	A	T	MI.11331	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	277	93	N	Y	Aac/Tac	-9,89	0	0	benign	0	neutral	1	neutral	2,81	neutral	-1,7	neutral	2,49	neutral_impact	-0,36	neutral	0,81	neutral	0,97	deleterious	0,67	8,66	0,18	0,45	neutral	0,13	neutral	0,15	neutral	0,16	neutral	0,24	5	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,07	high_impact	1,96	low_impact	-1,5	0,17	0,8	24,53	32,23	N	0,36	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3583	3583	A	G	MI.11332	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	277	93	N	D	Aac/Gac	-9,89	0	0	benign	0,01	neutral	0,2	neutral	2,78	neutral	0,01	neutral	-1,15	low_impact	1,34	neutral	0,8	neutral	0,65	deleterious	1,87	15,41	0,32	0,5	neutral	0,31	neutral	0,22	neutral	0,33	neutral	0,4	2	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	-0,06	medium_impact	-0,02	0,23	0,8	24,53	32,23	N	0,46	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3583	3583	A	C	MI.11333	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	277	93	N	H	Aac/Cac	-9,89	0	0	benign	0,01	neutral	0,54	neutral	2,76	neutral	-1,35	neutral	2,16	neutral_impact	0,14	neutral	0,71	neutral	0,97	neutral	-0,17	1,29	0,25	0,45	neutral	0,25	neutral	0,15	neutral	0,18	neutral	0,28	4	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,31	low_impact	-1,07	0,27	0,8	24,53	32,23	N	0,47	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3584	3584	A	T	MI.11334	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	278	93	N	I	aAc/aTc	-2,08	0	0	benign	0,01	neutral	0,4	neutral	2,78	neutral	-1,75	neutral	-0,71	neutral_impact	0,41	neutral	0,83	neutral	0,81	neutral	1,32	12,36	0,19	0,45	neutral	0,11	neutral	0,3	neutral	0,17	neutral	0,43	1	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,18	medium_impact	-0,83	0,11	0,8	24,53	32,23	N	0,44	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3584	3584	A	C	MI.11335	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	278	93	N	T	aAc/aCc	-2,08	0	0	benign	0,11	neutral	0,39	neutral	2,82	neutral	-0,24	neutral	-0,68	neutral_impact	0,12	neutral	0,84	neutral	0,8	deleterious	0,77	9,27	0,23	0,45	neutral	0,15	neutral	0,16	neutral	0,15	neutral	0,29	4	neutral	0,55	deleterious	0,64	neutral	-6	neutral	0,12	medium_impact	0,1	medium_impact	0,17	low_impact	-1,08	0,3	0,8	24,53	32,23	N	0,47	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3584	3584	A	G	MI.11336	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	278	93	N	S	aAc/aGc	-2,08	0	0	benign	0,01	neutral	0,4	neutral	2,81	neutral	0,56	neutral	-0,28	low_impact	0,83	neutral	0,79	neutral	0,79	deleterious	0,43	6,89	0,36	0,5	neutral	0,13	neutral	0,13	neutral	0,18	neutral	0,27	5	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,18	medium_impact	-0,46	0,24	0,8	24,53	32,23	N	0,51	P	0,27	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3585	3585	C	A	MI.11337	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	279	93	N	K	aaC/aaA	-0,01	0	0	benign	0,11	neutral	0,29	neutral	2,83	neutral	0,3	neutral	-0,8	low_impact	1,31	neutral	0,85	neutral	0,59	neutral	1,4	12,77	0,28	0,45	neutral	0,2	neutral	0,33	neutral	0,36	neutral	0,44	1	neutral	0,67	deleterious	0,59	neutral	-6	neutral	0,15	medium_impact	0,1	medium_impact	0,06	medium_impact	-0,04	0,28	0,8	24,53	32,23	N	0,39	N	0,49	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3585	3585	C	G	MI.11338	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	279	93	N	K	aaC/aaG	-0,01	0	0	benign	0,11	neutral	0,29	neutral	2,83	neutral	0,3	neutral	-0,8	low_impact	1,31	neutral	0,85	neutral	0,59	neutral	0,96	10,41	0,28	0,45	neutral	0,2	neutral	0,33	neutral	0,36	neutral	0,44	1	neutral	0,67	deleterious	0,59	neutral	-6	neutral	0,15	medium_impact	0,1	medium_impact	0,06	medium_impact	-0,04	0,28	0,8	24,53	32,23	N	0,39	N	0,49	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3586	3586	C	T	MI.11339	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	280	94	P	S	Ccc/Tcc	-2,77	0	0	benign	0,13	neutral	0,4	neutral	2,87	neutral	0,97	deleterious	-4,26	neutral_impact	0,45	neutral	0,87	neutral	0,89	deleterious	2,38	18,68	0,35	0,5	neutral	0,14	neutral	0,27	neutral	0,21	neutral	0,42	2	neutral	0,53	deleterious	0,64	neutral	-6	neutral	0,13	medium_impact	0,02	medium_impact	0,18	medium_impact	-0,8	0,05	0,8	22,96	23,16	N	0,38	N	0,62	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9059	9059	C	G	MI.1134	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	533	178	T	S	aCc/aGc	-0,1	0	0	benign	0,28	neutral	0,66	neutral	4,33	neutral	-1,8	neutral	-2,23	low_impact	0,9	neutral	0,81	neutral	0,59	deleterious	3,57	23,1	0,42	0,65	neutral	0,48	neutral	0,39	neutral	0,36	neutral	0,42	2	neutral	0,25	deleterious	0,69	neutral	-6	neutral	0,38	medium_impact	-0,37	medium_impact	0,45	medium_impact	-0,33	0,74	0,9	22,57	14,83	N	0,23	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3586	3586	C	G	MI.11340	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	280	94	P	A	Ccc/Gcc	-2,77	0	0	benign	0,12	neutral	0,5	neutral	2,85	neutral	0,8	deleterious	-4,69	neutral_impact	0,62	neutral	0,9	neutral	0,81	deleterious	1,93	15,77	0,26	0,45	neutral	0,17	neutral	0,29	neutral	0,4	neutral	0,43	1	neutral	0,41	deleterious	0,69	neutral	-6	neutral	0,13	medium_impact	0,06	medium_impact	0,28	medium_impact	-0,65	0,53	0,8	22,96	23,16	N	0,4	N	0,33	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3586	3586	C	A	MI.11341	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	280	94	P	T	Ccc/Acc	-2,77	0	0	possibly_damaging	0,74	neutral	0,39	neutral	2,82	neutral	0,34	deleterious	-4,31	low_impact	1,1	neutral	0,86	neutral	0,84	deleterious	2,59	20,1	0,22	0,45	neutral	0,17	neutral	0,39	neutral	0,24	neutral	0,45	1	neutral	0,76	neutral	0,33	neutral	-3	deleterious	0,44	low_impact	-1,18	medium_impact	0,17	medium_impact	-0,23	0,49	0,8	22,96	23,16	N	0,34	N	0,41	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3587	3587	C	G	MI.11342	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	281	94	P	R	cCc/cGc	0,22	0,04	0	probably_damaging	0,94	neutral	0,35	neutral	2,84	neutral	0,55	deleterious	-5,83	medium_impact	3,06	neutral	0,75	neutral	0,42	deleterious	3,59	23,2	0,12	0,4	neutral	0,21	disease	0,69	disease	0,54	disease	0,66	3	neutral	0,94	neutral	0,21	deleterious	1	deleterious	0,64	low_impact	-1,87	medium_impact	0,12	medium_impact	1,48	0,3	0,8	22,96	23,16	N	0,42	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3587	3587	C	T	MI.11343	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	281	94	P	L	cCc/cTc	0,22	0,04	0	possibly_damaging	0,83	neutral	0,65	neutral	2,79	neutral	-0,37	deleterious	-6,6	medium_impact	2,16	neutral	0,73	neutral	0,45	deleterious	4,34	24,1	0,2	0,45	neutral	0,25	disease	0,58	neutral	0,4	neutral	0,49	0	neutral	0,8	neutral	0,41	NA	0	deleterious	0,58	low_impact	-1,4	medium_impact	0,43	medium_impact	0,7	0,7	0,85	22,96	23,16	N	0,31	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3587	3587	C	A	MI.11344	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	281	94	P	H	cCc/cAc	0,22	0,04	0	probably_damaging	0,98	neutral	0,54	neutral	2,78	neutral	-0,77	deleterious	-5,96	medium_impact	2,63	neutral	0,75	neutral	0,39	deleterious	3,97	23,6	0,14	0,4	neutral	0,34	disease	0,62	neutral	0,35	neutral	0,49	0	neutral	0,97	neutral	0,28	deleterious	1	deleterious	0,66	low_impact	-2,34	medium_impact	0,31	medium_impact	1,11	0,28	0,8	22,96	23,16	N	0,28	N	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3589	3589	C	A	MI.11345	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	283	95	L	M	Ctg/Atg	-20	0	0	probably_damaging	1	neutral	0,3	neutral	2,59	neutral	-2,67	neutral	-0,96	medium_impact	1,96	neutral	0,83	neutral	0,62	deleterious	2,52	19,6	0,29	0,45	neutral	0,5	neutral	0,19	neutral	0,24	neutral	0,27	5	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,68	low_impact	-3,57	medium_impact	0,07	medium_impact	0,52	0,66	0,8	59,43	10,55	N	0,43	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3589	3589	C	G	MI.11346	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	283	95	L	V	Ctg/Gtg	-20	0	0	probably_damaging	1	neutral	0,54	neutral	2,66	neutral	-1,04	neutral	-1,38	medium_impact	2,06	neutral	0,84	neutral	0,61	deleterious	1,87	15,43	0,24	0,45	neutral	0,31	neutral	0,19	neutral	0,27	neutral	0,36	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,66	low_impact	-3,57	medium_impact	0,31	medium_impact	0,61	0,47	0,8	59,43	10,55	N	0,32	N	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3590	3590	T	G	MI.11347	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	284	95	L	R	cTg/cGg	-0,47	0	0	probably_damaging	1	neutral	0,32	neutral	2,52	deleterious	-3,96	deleterious	-4,8	high_impact	4,17	neutral	0,72	neutral	0,34	deleterious	4,12	23,8	0,04	0,35	disease	0,67	disease	0,84	disease	0,74	disease	0,78	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,09	high_impact	2,45	0,12	0,8	59,43	10,55	N	0,43	N	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3590	3590	T	A	MI.11348	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	284	95	L	Q	cTg/cAg	-0,47	0	0	probably_damaging	1	neutral	0,28	neutral	2,52	deleterious	-4,18	deleterious	-4,57	medium_impact	2,62	neutral	0,74	neutral	0,45	deleterious	4,12	23,8	0,06	0,35	disease	0,69	disease	0,69	disease	0,61	disease	0,58	2	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,78	low_impact	-3,57	medium_impact	0,05	medium_impact	1,1	0,16	0,8	59,43	10,55	N	0,31	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3590	3590	T	C	MI.11349	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	284	95	L	P	cTg/cCg	-0,47	0	0	probably_damaging	1	neutral	0,36	neutral	2,51	deleterious	-4,11	deleterious	-5,38	medium_impact	3,47	neutral	0,62	neutral	0,37	deleterious	3,85	23,4	0,05	0,35	neutral	0,32	disease	0,83	disease	0,74	disease	0,77	5	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-3,57	medium_impact	0,14	medium_impact	1,84	0,2	0,8	59,43	10,55	N	0,39	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9059	9059	C	A	MI.1135	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	533	178	T	N	aCc/aAc	-0,1	0	0	possibly_damaging	0,75	neutral	0,29	neutral	4,3	deleterious	-3,27	deleterious	-3,55	low_impact	1,75	neutral	0,82	neutral	0,5	deleterious	3,74	23,3	0,32	0,65	disease	0,69	disease	0,65	disease	0,52	disease	0,58	2	neutral	0,81	neutral	0,27	neutral	-3	deleterious	0,64	low_impact	-1,21	medium_impact	0,07	medium_impact	0,4	0,71	0,9	22,57	14,83	N	0,3	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3592	3592	G	C	MI.11350	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	286	96	V	L	Gtc/Ctc	-8,28	0	0	benign	0,01	neutral	0,66	neutral	2,73	neutral	-0,47	neutral	-0,62	neutral_impact	-0,52	neutral	0,84	neutral	0,92	deleterious	-0,02	2,42	0,22	0,45	neutral	0,13	neutral	0,25	neutral	0,14	neutral	0,4	2	neutral	0,33	deleterious	0,83	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,44	low_impact	-1,64	0,43	0,8	19,81	13,32	N	0,38	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3592	3592	G	T	MI.11351	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	286	96	V	F	Gtc/Ttc	-8,28	0	0	benign	0,38	neutral	0,71	neutral	2,6	neutral	-1,58	neutral	-2,11	neutral_impact	-0,63	neutral	0,79	neutral	0,66	deleterious	1,96	15,95	0,09	0,4	neutral	0,17	neutral	0,45	neutral	0,18	neutral	0,43	1	neutral	0,29	deleterious	0,67	neutral	-6	neutral	0,23	medium_impact	-0,55	medium_impact	0,49	low_impact	-1,74	0,29	0,8	19,81	13,32	N	0,3	N	0,51	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3592	3592	G	A	MI.11352	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	286	96	V	I	Gtc/Atc	-8,28	0	0	benign	0,01	neutral	0,4	neutral	2,72	neutral	-0,26	neutral	-0,36	neutral_impact	-1,3	neutral	0,68	neutral	0,93	neutral	-1,09	0,01	0,37	0,5	neutral	0,14	neutral	0,08	neutral	0,15	neutral	0,29	4	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,07	medium_impact	1,12	medium_impact	0,18	low_impact	-2,32	0,56	0,8	19,81	13,32	N	0,5	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3593	3593	T	C	MI.11353	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	287	96	V	A	gTc/gCc	-0,7	0	0,01	benign	0,01	neutral	0,51	neutral	2,66	neutral	0,02	neutral	0,12	neutral_impact	-1,45	neutral	0,85	neutral	0,92	neutral	-0,59	0,13	0,16	0,45	neutral	0,12	neutral	0,12	neutral	0,21	neutral	0,28	4	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,29	low_impact	-2,45	0,12	0,8	19,81	13,32	N	0,32	N	0,29	polymorphism	1	0,01	rs2854134	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3593	3593	T	G	MI.11354	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	287	96	V	G	gTc/gGc	-0,7	0	0,01	benign	0,26	neutral	0,33	neutral	2,57	neutral	-2,74	deleterious	-2,67	neutral_impact	0,63	neutral	0,74	neutral	0,52	deleterious	2,17	17,29	0,05	0,35	neutral	0,44	neutral	0,33	neutral	0,45	neutral	0,46	1	neutral	0,6	deleterious	0,54	neutral	-6	neutral	0,23	medium_impact	-0,32	medium_impact	0,1	medium_impact	-0,64	0,2	0,8	19,81	13,32	N	0,38	N	0,5	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3593	3593	T	A	MI.11355	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	287	96	V	D	gTc/gAc	-0,7	0	0,01	possibly_damaging	0,55	neutral	0,21	neutral	2,56	deleterious	-4,28	deleterious	-3	low_impact	1,22	neutral	0,76	neutral	0,48	deleterious	4,06	23,7	0,03	0,35	disease	0,58	disease	0,58	disease	0,54	disease	0,63	3	neutral	0,78	neutral	0,33	neutral	-3	deleterious	0,46	medium_impact	-0,83	medium_impact	-0,05	medium_impact	-0,12	0,03	0,8	19,81	13,32	N	0,32	N	0,49	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3595	3595	A	T	MI.11356	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	289	97	N	Y	Aac/Tac	-6,9	0	0	probably_damaging	0,99	neutral	1	neutral	2,64	deleterious	-3,45	deleterious	-4,96	medium_impact	1,96	neutral	0,71	damaging	0,1	deleterious	3,64	23,2	0,16	0,45	disease	0,57	disease	0,64	disease	0,65	disease	0,66	3	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,74	low_impact	-2,62	high_impact	1,96	medium_impact	0,52	0,12	0,8	15,09	25,31	N	0,18	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3595	3595	A	C	MI.11357	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	289	97	N	H	Aac/Cac	-6,9	0	0	probably_damaging	0,99	neutral	0,54	neutral	2,66	neutral	-2,55	deleterious	-2,8	medium_impact	2,55	neutral	0,8	damaging	0,11	deleterious	3,02	22,3	0,36	0,5	neutral	0,43	disease	0,63	disease	0,55	disease	0,67	3	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,71	low_impact	-2,62	medium_impact	0,31	medium_impact	1,04	0,1	0,8	15,09	25,31	N	0,18	N	0,79	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3595	3595	A	G	MI.11358	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	289	97	N	D	Aac/Gac	-6,9	0	0	benign	0,17	neutral	0,2	neutral	2,98	neutral	1,03	neutral	1,16	neutral_impact	-0,56	neutral	0,81	neutral	0,7	neutral	1,04	10,89	0,54	0,6	neutral	0,13	neutral	0,08	neutral	0,23	neutral	0,26	5	neutral	0,77	deleterious	0,52	neutral	-6	neutral	0,17	medium_impact	-0,1	medium_impact	-0,06	low_impact	-1,68	0,28	0,8	15,09	25,31	N	0,41	N	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3596	3596	A	T	MI.11359	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	290	97	N	I	aAc/aTc	2,75	0,99	0	probably_damaging	0,98	neutral	0,39	neutral	2,65	deleterious	-3,1	deleterious	-5,32	medium_impact	2,39	neutral	0,69	damaging	0,12	deleterious	4,39	24,1	0,17	0,45	disease	0,53	disease	0,74	disease	0,58	disease	0,7	4	neutral	0,98	neutral	0,21	deleterious	1	deleterious	0,74	low_impact	-2,34	medium_impact	0,17	medium_impact	0,9	0,08	0,8	15,09	25,31	N	0,44	N	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9059	9059	C	T	MI.1136	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	533	178	T	I	aCc/aTc	-0,1	0	0	possibly_damaging	0,61	neutral	0,58	neutral	4,46	neutral	-0,85	deleterious	-3,13	low_impact	1,08	neutral	0,86	neutral	0,59	deleterious	2,99	22,2	0,28	0,65	neutral	0,43	disease	0,66	neutral	0,39	neutral	0,48	0	neutral	0,55	deleterious	0,49	neutral	-3	deleterious	0,55	medium_impact	-0,94	medium_impact	0,37	medium_impact	-0,17	0,75	0,9	22,57	14,83	N	0,2	N	0,62	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3596	3596	A	G	MI.11360	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	290	97	N	S	aAc/aGc	2,75	0,99	0	possibly_damaging	0,81	neutral	0,4	neutral	2,78	neutral	-0,23	neutral	-2,18	low_impact	1,27	neutral	0,85	damaging	0,16	deleterious	3,48	23,1	0,47	0,55	neutral	0,14	neutral	0,32	neutral	0,3	neutral	0,43	1	neutral	0,82	neutral	0,3	neutral	-3	deleterious	0,62	low_impact	-1,34	medium_impact	0,18	medium_impact	-0,08	0,17	0,8	15,09	25,31	N	0,44	N	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3596	3596	A	C	MI.11361	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	290	97	N	T	aAc/aCc	2,75	0,99	0	probably_damaging	0,94	neutral	0,39	neutral	2,71	neutral	-1,15	deleterious	-3,11	medium_impact	2,21	neutral	0,68	damaging	0,12	deleterious	3,8	23,4	0,28	0,45	neutral	0,29	disease	0,51	neutral	0,33	neutral	0,47	1	neutral	0,94	neutral	0,23	deleterious	1	deleterious	0,67	low_impact	-1,87	medium_impact	0,17	medium_impact	0,74	0,15	0,8	15,09	25,31	N	0,42	N	0,75	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3597	3597	C	A	MI.11362	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	291	97	N	K	aaC/aaA	6,42	1	0	probably_damaging	0,91	neutral	0,29	neutral	2,73	neutral	-0,91	deleterious	-3,1	medium_impact	2,9	neutral	0,84	damaging	0,12	deleterious	4,43	24,2	0,36	0,5	neutral	0,21	disease	0,72	disease	0,65	disease	0,7	4	neutral	0,93	neutral	0,19	deleterious	1	deleterious	0,68	low_impact	-1,69	medium_impact	0,06	medium_impact	1,34	0,28	0,8	15,09	25,31	P	0,55	P	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3597	3597	C	G	MI.11363	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	291	97	N	K	aaC/aaG	6,42	1	0	probably_damaging	0,91	neutral	0,29	neutral	2,73	neutral	-0,91	deleterious	-3,1	medium_impact	2,9	neutral	0,84	damaging	0,12	deleterious	3,95	23,6	0,36	0,5	neutral	0,21	disease	0,72	disease	0,65	disease	0,7	4	neutral	0,93	neutral	0,19	deleterious	1	deleterious	0,68	low_impact	-1,69	medium_impact	0,06	medium_impact	1,34	0,28	0,8	15,09	25,31	N	0,55	P	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3598	3598	C	A	MI.11364	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	292	98	L	I	Ctc/Atc	-1,16	0	0	benign	0,08	neutral	0,39	neutral	2,68	neutral	-0,8	neutral	-1,24	low_impact	1,24	neutral	0,88	neutral	0,81	deleterious	3,01	22,3	0,36	0,5	neutral	0,23	neutral	0,41	neutral	0,22	neutral	0,45	1	neutral	0,56	deleterious	0,66	neutral	-6	neutral	0,18	medium_impact	0,25	medium_impact	0,17	medium_impact	-0,11	0,47	0,8	27,36	38,79	N	0,42	N	0,32	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3598	3598	C	G	MI.11365	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	292	98	L	V	Ctc/Gtc	-1,16	0	0	benign	0,4	neutral	0,5	neutral	2,67	neutral	-0,9	neutral	-1,88	low_impact	1,92	neutral	0,73	neutral	0,68	deleterious	3,31	22,9	0,38	0,5	neutral	0,21	neutral	0,45	neutral	0,27	neutral	0,46	1	neutral	0,44	deleterious	0,55	neutral	-6	neutral	0,26	medium_impact	-0,59	medium_impact	0,28	medium_impact	0,49	0,49	0,8	27,36	38,79	N	0,41	N	0,31	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3598	3598	C	T	MI.11366	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	292	98	L	F	Ctc/Ttc	-1,16	0	0	benign	0,05	neutral	0,7	neutral	2,67	neutral	-0,92	deleterious	-2,92	neutral_impact	0,54	neutral	0,81	neutral	0,8	deleterious	2,77	21,2	0,3	0,45	neutral	0,22	neutral	0,24	neutral	0,2	neutral	0,43	1	neutral	0,22	deleterious	0,83	neutral	-6	neutral	0,17	medium_impact	0,45	medium_impact	0,48	medium_impact	-0,72	0,55	0,8	27,36	38,79	N	0,3	N	0,04	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3599	3599	T	A	MI.11367	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	293	98	L	H	cTc/cAc	-2,08	0	0	probably_damaging	0,98	neutral	0,54	neutral	2,51	deleterious	-4,05	deleterious	-5,45	medium_impact	3,26	neutral	0,73	neutral	0,51	deleterious	4,08	23,7	0,05	0,35	disease	0,6	disease	0,78	disease	0,7	disease	0,75	5	neutral	0,97	neutral	0,28	deleterious	1	deleterious	0,77	low_impact	-2,34	medium_impact	0,31	medium_impact	1,66	0,16	0,8	27,36	38,79	N	0,28	N	0,75	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3599	3599	T	C	MI.11368	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	293	98	L	P	cTc/cCc	-2,08	0	0	probably_damaging	0,96	neutral	0,21	neutral	2,53	deleterious	-3,34	deleterious	-5,47	medium_impact	2,61	damaging	0,6	neutral	0,42	deleterious	3,84	23,4	0,02	0,35	neutral	0,47	disease	0,85	disease	0,73	disease	0,78	6	neutral	0,98	neutral	0,13	deleterious	1	deleterious	0,8	low_impact	-2,05	medium_impact	-0,05	medium_impact	1,09	0,1	0,8	27,36	38,79	N	0,32	N	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3599	3599	T	G	MI.11369	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	293	98	L	R	cTc/cGc	-2,08	0	0	probably_damaging	0,93	neutral	0,35	neutral	2,52	deleterious	-3,38	deleterious	-4,63	high_impact	3,81	neutral	0,67	neutral	0,47	deleterious	4,15	23,8	0,02	0,35	neutral	0,5	disease	0,87	disease	0,74	disease	0,79	6	neutral	0,94	neutral	0,21	deleterious	2	deleterious	0,78	low_impact	-1,81	medium_impact	0,12	high_impact	2,14	0,1	0,8	27,36	38,79	N	0,43	N	0,82	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9061	9061	C	G	MI.1137	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	535	179	L	V	Cta/Gta	-13,29	0	0	benign	0,28	neutral	0,36	neutral	4,4	neutral	-1,05	neutral	-1,92	low_impact	1,25	neutral	0,83	neutral	0,68	deleterious	0,69	8,79	0,47	0,65	disease	0,52	neutral	0,35	neutral	0,42	neutral	0,36	3	neutral	0,56	deleterious	0,54	neutral	-6	neutral	0,33	medium_impact	-0,37	medium_impact	0,15	medium_impact	-0,03	0,7	0,9	44,25	7,93	N	0,36	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3601	3601	A	T	MI.11370	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	295	99	N	Y	Aac/Tac	-5,3	0	0	probably_damaging	1	neutral	1	neutral	2,54	deleterious	-3,95	deleterious	-7,32	high_impact	3,58	neutral	0,74	damaging	0,1	deleterious	3,66	23,2	0,14	0,4	disease	0,59	disease	0,86	disease	0,72	disease	0,76	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,8	low_impact	-3,57	high_impact	1,96	medium_impact	1,94	0,13	0,8	58,18	10,18	N	0,26	N	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3601	3601	A	C	MI.11371	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	295	99	N	H	Aac/Cac	-5,3	0	0	probably_damaging	1	neutral	0,52	neutral	2,56	deleterious	-3,14	deleterious	-4,57	high_impact	3,72	neutral	0,79	damaging	0,16	deleterious	3,01	22,3	0,42	0,5	neutral	0,47	disease	0,83	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,29	high_impact	2,06	0,14	0,8	58,18	10,18	N	0,25	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3601	3601	A	G	MI.11372	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	295	99	N	D	Aac/Gac	-5,3	0	0	probably_damaging	1	neutral	0,2	neutral	2,63	neutral	-1,47	deleterious	-4,56	medium_impact	2,77	neutral	0,79	damaging	0,14	deleterious	3,74	23,3	0,48	0,55	neutral	0,22	disease	0,72	disease	0,66	disease	0,53	1	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	-0,06	medium_impact	1,23	0,28	0,8	58,18	10,18	N	0,33	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3602	3602	A	T	MI.11373	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	296	99	N	I	aAc/aTc	6,65	1	0	probably_damaging	1	neutral	0,38	neutral	2,55	deleterious	-3,52	deleterious	-8,23	high_impact	3,58	neutral	0,75	damaging	0,12	deleterious	4,38	24,1	0,14	0,4	disease	0,54	disease	0,9	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,16	medium_impact	1,94	0,1	0,8	58,18	10,18	P	0,59	P	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3602	3602	A	G	MI.11374	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	296	99	N	S	aAc/aGc	6,65	1	0	probably_damaging	1	neutral	0,41	neutral	2,67	neutral	-0,99	deleterious	-4,52	medium_impact	2,61	neutral	0,75	damaging	0,19	deleterious	3,51	23,1	0,5	0,6	neutral	0,23	disease	0,72	neutral	0,44	neutral	0,49	0	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,19	medium_impact	1,09	0,17	0,8	58,18	10,18	P	0,57	P	0,9	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3602	3602	A	C	MI.11375	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	296	99	N	T	aAc/aCc	6,65	1	0	probably_damaging	1	neutral	0,4	neutral	2,59	neutral	-2,1	deleterious	-5,46	medium_impact	3,33	neutral	0,7	damaging	0,17	deleterious	3,8	23,4	0,31	0,45	neutral	0,25	disease	0,81	disease	0,67	disease	0,63	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	0,18	medium_impact	1,72	0,18	0,8	58,18	10,18	P	0,55	P	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3603	3603	C	A	MI.11376	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	297	99	N	K	aaC/aaA	8,49	1	0	probably_damaging	1	neutral	0,28	neutral	2,64	neutral	-1,36	deleterious	-5,47	medium_impact	2,38	neutral	0,72	damaging	0,1	deleterious	4,42	24,2	0,38	0,5	neutral	0,23	disease	0,87	disease	0,67	disease	0,54	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,05	medium_impact	0,89	0,36	0,8	58,18	10,18	N	0,53	P	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3603	3603	C	G	MI.11377	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	297	99	N	K	aaC/aaG	8,49	1	0	probably_damaging	1	neutral	0,28	neutral	2,64	neutral	-1,36	deleterious	-5,47	medium_impact	2,38	neutral	0,72	damaging	0,1	deleterious	3,95	23,6	0,38	0,5	neutral	0,23	disease	0,87	disease	0,67	disease	0,54	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,05	medium_impact	0,89	0,36	0,8	58,18	10,18	N	0,53	P	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3604	3604	C	A	MI.11378	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	298	100	L	M	Cta/Ata	-1,85	0	0	benign	0,31	neutral	0,25	neutral	2,48	neutral	-2,72	neutral	-1,52	medium_impact	2,42	neutral	0,84	neutral	0,74	deleterious	2,74	21	0,34	0,5	neutral	0,39	neutral	0,48	neutral	0,36	neutral	0,45	1	neutral	0,7	deleterious	0,47	neutral	-3	neutral	0,37	medium_impact	-0,43	medium_impact	0,01	medium_impact	0,93	0,67	0,85	52,52	9,59	N	0,43	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3604	3604	C	G	MI.11379	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	298	100	L	V	Cta/Gta	-1,85	0	0	possibly_damaging	0,64	neutral	0,52	neutral	2,63	neutral	-0,94	deleterious	-2,62	medium_impact	2,23	neutral	0,67	damaging	0,13	deleterious	3,31	22,9	0,29	0,45	neutral	0,19	disease	0,51	neutral	0,38	neutral	0,42	2	neutral	0,61	neutral	0,44	NA	0	deleterious	0,56	medium_impact	-0,99	medium_impact	0,29	medium_impact	0,76	0,49	0,8	52,52	9,59	N	0,27	N	0,84	polymorphism	1	0,09	rs28647976	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9061	9061	C	A	MI.1138	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	535	179	L	M	Cta/Ata	-13,29	0	0	benign	0,12	neutral	0,5	neutral	4,31	neutral	-2,17	neutral	-1,13	low_impact	1,21	neutral	0,9	neutral	0,63	deleterious	0,8	9,46	0,32	0,65	disease	0,7	neutral	0,24	neutral	0,25	disease	0,58	1	neutral	0,41	deleterious	0,69	neutral	-6	neutral	0,23	medium_impact	0,07	medium_impact	0,29	medium_impact	-0,06	0,64	0,9	44,25	7,93	N	0,39	N	0,96	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3605	3605	T	G	MI.11380	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	299	100	L	R	cTa/cGa	-0,93	0	0	probably_damaging	0,96	neutral	0,35	neutral	2,44	deleterious	-3,98	deleterious	-5,32	high_impact	4,43	neutral	0,74	damaging	0,11	deleterious	4,09	23,7	0,04	0,35	neutral	0,49	disease	0,89	disease	0,75	disease	0,79	6	neutral	0,96	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-2,05	medium_impact	0,12	high_impact	2,68	0,19	0,8	52,52	9,59	N	0,5	N	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3605	3605	T	A	MI.11381	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	299	100	L	Q	cTa/cAa	-0,93	0	0	probably_damaging	0,96	neutral	0,3	neutral	2,44	deleterious	-4,05	deleterious	-5,26	high_impact	4,43	neutral	0,72	damaging	0,12	deleterious	4	23,6	0,06	0,35	disease	0,5	disease	0,83	disease	0,61	disease	0,68	4	neutral	0,96	neutral	0,17	deleterious	2	deleterious	0,77	low_impact	-2,05	medium_impact	0,07	high_impact	2,68	0,2	0,8	52,52	9,59	N	0,42	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3605	3605	T	C	MI.11382	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	299	100	L	P	cTa/cCa	-0,93	0	0	probably_damaging	0,98	neutral	0,25	neutral	2,43	deleterious	-4,63	deleterious	-6,24	high_impact	4,43	neutral	0,75	damaging	0,12	deleterious	3,81	23,4	0,04	0,35	disease	0,59	disease	0,84	disease	0,74	disease	0,77	5	deleterious	0,98	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-2,34	medium_impact	0,01	high_impact	2,68	0,28	0,8	52,52	9,59	N	0,45	N	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3607	3607	G	A	MI.11383	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	301	101	G	S	Ggc/Agc	-0,93	0,02	0	possibly_damaging	0,78	neutral	0,44	neutral	2,6	neutral	-1,14	deleterious	-3,66	low_impact	0,86	neutral	0,84	neutral	0,84	deleterious	2,74	21	0,14	0,4	neutral	0,29	disease	0,57	neutral	0,39	neutral	0,44	1	neutral	0,77	neutral	0,33	neutral	-3	deleterious	0,63	low_impact	-1,27	medium_impact	0,22	medium_impact	-0,44	0,68	0,85	53,77	9,5	N	0,3	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3607	3607	G	T	MI.11384	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	301	101	G	C	Ggc/Tgc	-0,93	0,02	0	probably_damaging	1	neutral	0,18	neutral	2,41	deleterious	-4,96	deleterious	-6,65	high_impact	4,16	neutral	0,69	damaging	0,1	deleterious	4,02	23,6	0,05	0,35	disease	0,84	disease	0,91	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	-0,09	high_impact	2,44	0,15	0,8	53,77	9,5	N	0,34	N	0,98	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3607	3607	G	C	MI.11385	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	301	101	G	R	Ggc/Cgc	-0,93	0,02	0	probably_damaging	1	neutral	0,35	neutral	2,44	deleterious	-3,19	deleterious	-5,93	high_impact	4,16	neutral	0,7	damaging	0,09	deleterious	3,76	23,4	0,04	0,35	neutral	0,44	disease	0,91	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,12	high_impact	2,44	0,34	0,8	53,77	9,5	N	0,46	N	0,99	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3608	3608	G	C	MI.11386	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	302	101	G	A	gGc/gCc	2,75	0,99	0	probably_damaging	0,95	neutral	0,52	neutral	2,54	neutral	-1,66	deleterious	-4,08	medium_impact	2,68	neutral	0,83	neutral	0,41	deleterious	2,96	22,1	0,16	0,45	neutral	0,3	disease	0,69	disease	0,56	neutral	0,5	0	neutral	0,94	neutral	0,29	deleterious	1	deleterious	0,75	low_impact	-1,95	medium_impact	0,29	medium_impact	1,15	0,29	0,8	53,77	9,5	N	0,43	N	0,76	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3608	3608	G	T	MI.11387	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	302	101	G	V	gGc/gTc	2,75	0,99	0	probably_damaging	0,99	neutral	0,53	neutral	2,44	deleterious	-3,24	deleterious	-6,74	high_impact	3,69	neutral	0,69	damaging	0,12	deleterious	3,65	23,2	0,05	0,35	disease	0,56	disease	0,86	disease	0,67	disease	0,72	4	deleterious	0,99	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-2,62	medium_impact	0,3	high_impact	2,03	0,13	0,8	53,77	9,5	N	0,44	N	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3608	3608	G	A	MI.11388	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	302	101	G	D	gGc/gAc	2,75	0,99	0	probably_damaging	0,99	neutral	0,22	neutral	2,46	neutral	-2,77	deleterious	-5,08	high_impact	3,6	neutral	0,75	damaging	0,11	deleterious	3,8	23,4	0,06	0,35	neutral	0,27	disease	0,9	disease	0,75	disease	0,77	5	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,78	low_impact	-2,62	medium_impact	-0,03	medium_impact	1,96	0,09	0,8	53,77	9,5	N	0,5	N	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3610	3610	C	G	MI.11389	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	304	102	L	V	Ctc/Gtc	-4,84	0	0	benign	0,08	neutral	0,56	neutral	2,92	neutral	-0,66	neutral	-0,19	low_impact	1,4	neutral	0,88	neutral	0,94	neutral	1,5	13,32	0,26	0,45	neutral	0,15	neutral	0,17	neutral	0,31	neutral	0,3	4	neutral	0,37	deleterious	0,74	neutral	-6	neutral	0,13	medium_impact	0,25	medium_impact	0,33	medium_impact	0,03	0,66	0,8	29,25	35,19	N	0,36	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9062	9062	T	A	MI.1139	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	536	179	L	Q	cTa/cAa	-0,33	0	0	possibly_damaging	0,82	neutral	0,21	neutral	4,31	neutral	-2,99	deleterious	-4,1	medium_impact	2	neutral	0,82	neutral	0,41	deleterious	4	23,6	0,19	0,65	disease	0,82	disease	0,62	neutral	0,44	disease	0,54	1	neutral	0,89	neutral	0,2	NA	0	deleterious	0,74	low_impact	-1,38	medium_impact	-0,03	medium_impact	0,62	0,7	0,9	44,25	7,93	N	0,32	N	0,98	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3610	3610	C	T	MI.11390	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	304	102	L	F	Ctc/Ttc	-4,84	0	0	probably_damaging	0,91	neutral	0,75	neutral	2,61	neutral	-2,75	neutral	-2,41	low_impact	1,72	neutral	0,75	neutral	0,32	deleterious	3,89	23,5	0,21	0,45	neutral	0,25	disease	0,54	neutral	0,39	neutral	0,46	1	neutral	0,9	neutral	0,42	neutral	-2	deleterious	0,66	low_impact	-1,69	medium_impact	0,54	medium_impact	0,31	0,34	0,8	29,25	35,19	N	0,21	N	0,44	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3610	3610	C	A	MI.11391	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	304	102	L	I	Ctc/Atc	-4,84	0	0	benign	0,08	neutral	0,43	neutral	2,86	neutral	-0,64	neutral	0,35	neutral_impact	0,1	neutral	0,89	neutral	0,92	neutral	1,27	12,1	0,26	0,45	neutral	0,17	neutral	0,08	neutral	0,25	neutral	0,28	4	neutral	0,52	deleterious	0,68	neutral	-6	neutral	0,13	medium_impact	0,25	medium_impact	0,21	low_impact	-1,1	0,56	0,8	29,25	35,19	N	0,49	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3611	3611	T	G	MI.11392	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	305	102	L	R	cTc/cGc	-1,62	0	0	probably_damaging	0,95	neutral	0,33	neutral	2,59	deleterious	-4,26	deleterious	-4,54	high_impact	4,03	neutral	0,71	damaging	0,18	deleterious	4,11	23,7	0,01	0,35	disease	0,59	disease	0,84	disease	0,7	disease	0,78	6	neutral	0,96	neutral	0,19	deleterious	2	deleterious	0,81	low_impact	-1,95	medium_impact	0,1	high_impact	2,33	0,19	0,8	29,25	35,19	N	0,35	N	0,81	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3611	3611	T	A	MI.11393	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	305	102	L	H	cTc/cAc	-1,62	0	0	probably_damaging	0,98	neutral	0,51	neutral	2,57	deleterious	-4,81	deleterious	-4,93	high_impact	3,68	neutral	0,73	damaging	0,22	deleterious	4,05	23,7	0,03	0,35	disease	0,67	disease	0,74	disease	0,61	disease	0,7	4	deleterious	0,98	neutral	0,27	deleterious	2	deleterious	0,78	low_impact	-2,34	medium_impact	0,29	high_impact	2,03	0,31	0,8	29,25	35,19	N	0,31	N	0,68	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3611	3611	T	C	MI.11394	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	305	102	L	P	cTc/cCc	-1,62	0	0	probably_damaging	0,98	neutral	0,21	neutral	2,58	deleterious	-4,39	deleterious	-4,8	medium_impact	3,48	neutral	0,7	damaging	0,18	deleterious	3,81	23,4	0,02	0,35	disease	0,67	disease	0,87	disease	0,71	disease	0,78	6	deleterious	0,98	neutral	0,12	deleterious	1	deleterious	0,85	low_impact	-2,34	medium_impact	-0,05	medium_impact	1,85	0,36	0,8	29,25	35,19	N	0,3	N	0,9	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3613	3613	C	A	MI.11395	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	307	103	L	M	Cta/Ata	-8,05	0	0	possibly_damaging	0,76	neutral	0,23	neutral	2,07	deleterious	-3,77	neutral	-1,76	medium_impact	3,04	neutral	0,78	damaging	0,27	deleterious	3,62	23,2	0,09	0,4	disease	0,55	disease	0,54	neutral	0,44	neutral	0,47	1	neutral	0,85	neutral	0,24	NA	0	deleterious	0,65	low_impact	-1,22	medium_impact	-0,02	medium_impact	1,47	0,44	0,8	60,69	9,64	N	0,32	N	0,89	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3613	3613	C	G	MI.11396	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	307	103	L	V	Cta/Gta	-8,05	0	0	possibly_damaging	0,9	neutral	0,51	neutral	2,12	deleterious	-3,06	deleterious	-2,69	medium_impact	3,19	neutral	0,79	damaging	0,13	deleterious	3,3	22,9	0,09	0,35	neutral	0,39	disease	0,56	disease	0,59	disease	0,56	1	neutral	0,89	neutral	0,31	NA	0	deleterious	0,7	low_impact	-1,65	medium_impact	0,29	medium_impact	1,6	0,52	0,8	60,69	9,64	N	0,2	N	0,84	polymorphism	1	0,23	rs28531858	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3614	3614	T	G	MI.11397	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	308	103	L	R	cTa/cGa	-0,47	0	0	probably_damaging	0,98	neutral	0,36	neutral	2,01	deleterious	-6,02	deleterious	-5,46	high_impact	4,84	neutral	0,76	damaging	0,11	deleterious	4,11	23,7	0,02	0,35	disease	0,83	disease	0,88	disease	0,76	disease	0,82	6	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,88	low_impact	-2,34	medium_impact	0,14	high_impact	3,04	0,17	0,8	60,69	9,64	P	0,7	P	1	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3614	3614	T	A	MI.11398	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	308	103	L	Q	cTa/cAa	-0,47	0	0	probably_damaging	0,99	neutral	0,31	neutral	2,01	deleterious	-5,96	deleterious	-5,45	high_impact	4,84	neutral	0,76	damaging	0,12	deleterious	3,99	23,6	0,02	0,35	disease	0,83	disease	0,84	disease	0,65	disease	0,74	5	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,83	low_impact	-2,62	medium_impact	0,08	high_impact	3,04	0,26	0,8	60,69	9,64	P	0,62	P	0,99	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3614	3614	T	C	MI.11399	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	308	103	L	P	cTa/cCa	-0,47	0	0	probably_damaging	1	neutral	0,22	neutral	2,01	deleterious	-6,6	deleterious	-6,38	high_impact	4,04	neutral	0,78	damaging	0,14	deleterious	3,81	23,4	0,02	0,35	disease	0,8	disease	0,84	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,03	high_impact	2,34	0,27	0,8	60,69	9,64	N	0,36	N	1	polymorphism	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8579	8579	C	G	MI.114	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	53	18	P	R	cCc/cGc	1,29	0,83	0	probably_damaging	1	deleterious	0,01	neutral	4,59	neutral	-0,09	deleterious	-7,67	high_impact	3,8	neutral	0,73	neutral	0,44	deleterious	3,34	22,9	0,25	0,65	disease	0,72	disease	0,92	disease	0,78	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,6	medium_impact	-0,84	high_impact	2,16	0,75	0,9	21,24	15,57	N	0,38	N	0,93	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9062	9062	T	C	MI.1140	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	536	179	L	P	cTa/cCa	-0,33	0	0	probably_damaging	0,9	neutral	0,31	neutral	4,32	deleterious	-3,45	deleterious	-4,65	low_impact	0,97	neutral	0,73	neutral	0,28	deleterious	3,9	23,5	0,17	0,65	neutral	0,42	disease	0,73	disease	0,59	disease	0,55	1	neutral	0,92	neutral	0,21	neutral	-2	deleterious	0,74	low_impact	-1,66	medium_impact	0,1	medium_impact	-0,27	0,57	0,9	44,25	7,93	N	0,25	N	1	polymorphism	1	0,07	.	.	.	.	.	.	COSM1155690	.	.	.	.	.	.	.	.
chrM	3616	3616	T	G	MI.11400	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	310	104	F	V	Ttt/Gtt	-1,62	0	0	probably_damaging	1	neutral	0,58	neutral	2,55	neutral	-1,69	deleterious	-6,32	medium_impact	2,81	neutral	0,68	damaging	0,17	deleterious	3,82	23,4	0,11	0,4	neutral	0,18	disease	0,86	disease	0,59	disease	0,65	3	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,35	medium_impact	1,27	0,28	0,8	59,43	10,27	N	0,27	N	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3616	3616	T	A	MI.11401	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	310	104	F	I	Ttt/Att	-1,62	0	0	probably_damaging	1	neutral	0,49	neutral	2,52	neutral	-2,07	deleterious	-5,41	medium_impact	2,88	neutral	0,76	damaging	0,22	deleterious	4,26	23,9	0,13	0,4	neutral	0,27	disease	0,86	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	0,27	medium_impact	1,33	0,44	0,8	59,43	10,27	N	0,34	N	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3616	3616	T	C	MI.11402	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	310	104	F	L	Ttt/Ctt	-1,62	0	0	probably_damaging	1	neutral	0,97	neutral	2,72	neutral	-0,38	deleterious	-5,41	medium_impact	2,31	neutral	0,75	damaging	0,19	deleterious	3,85	23,4	0,16	0,45	neutral	0,16	disease	0,82	neutral	0,42	neutral	0,5	0	deleterious	1	deleterious	0,49	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	1,12	medium_impact	0,83	0,49	0,8	59,43	10,27	N	0,28	N	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3617	3617	T	A	MI.11403	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	311	104	F	Y	tTt/tAt	3,44	1	0	probably_damaging	1	neutral	1	neutral	2,57	neutral	-1,5	deleterious	-2,72	medium_impact	1,97	neutral	0,79	damaging	0,19	deleterious	4,21	23,9	0,17	0,45	neutral	0,25	disease	0,71	neutral	0,44	neutral	0,49	0	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,73	low_impact	-3,57	high_impact	1,96	medium_impact	0,53	0,51	0,8	59,43	10,27	N	0,38	N	0,88	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3617	3617	T	C	MI.11404	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	311	104	F	S	tTt/tCt	3,44	1	0	probably_damaging	1	neutral	0,49	neutral	2,46	deleterious	-3,38	deleterious	-7,26	high_impact	3,65	neutral	0,72	damaging	0,21	deleterious	4,2	23,9	0,05	0,35	neutral	0,4	disease	0,88	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,27	medium_impact	2	0,33	0,8	59,43	10,27	N	0,49	N	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3617	3617	T	G	MI.11405	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	311	104	F	C	tTt/tGt	3,44	1	0	probably_damaging	1	neutral	0,17	neutral	2,43	deleterious	-4,82	deleterious	-7,27	high_impact	3,85	neutral	0,74	damaging	0,16	deleterious	4	23,6	0,05	0,35	disease	0,6	disease	0,9	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	-0,11	high_impact	2,17	0,17	0,8	59,43	10,27	P	0,55	P	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3618	3618	T	A	MI.11406	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	312	104	F	L	ttT/ttA	7,34	1	0	probably_damaging	1	neutral	0,97	neutral	2,72	neutral	-0,38	deleterious	-5,41	medium_impact	2,31	neutral	0,75	damaging	0,19	deleterious	4,36	24,1	0,16	0,45	neutral	0,16	disease	0,82	neutral	0,42	neutral	0,5	0	deleterious	1	deleterious	0,49	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	1,12	medium_impact	0,83	0,49	0,8	59,43	10,27	N	0,46	N	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3618	3618	T	G	MI.11407	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	312	104	F	L	ttT/ttG	7,34	1	0	probably_damaging	1	neutral	0,97	neutral	2,72	neutral	-0,38	deleterious	-5,41	medium_impact	2,31	neutral	0,75	damaging	0,19	deleterious	4,25	23,9	0,16	0,45	neutral	0,16	disease	0,82	neutral	0,42	neutral	0,5	0	deleterious	1	deleterious	0,49	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	1,12	medium_impact	0,83	0,49	0,8	59,43	10,27	N	0,46	N	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3619	3619	A	G	MI.11408	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	313	105	I	V	Att/Gtt	-3,23	0	0	benign	0,04	neutral	0,45	neutral	2,75	neutral	-0,21	neutral	-0,52	low_impact	1,5	neutral	0,89	neutral	0,79	neutral	1,78	14,87	0,28	0,45	neutral	0,21	neutral	0,34	neutral	0,35	neutral	0,44	1	neutral	0,52	deleterious	0,71	neutral	-6	neutral	0,12	medium_impact	0,55	medium_impact	0,23	medium_impact	0,12	0,48	0,8	24,21	35,91	N	0,38	N	0,44	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3619	3619	A	T	MI.11409	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	313	105	I	F	Att/Ttt	-3,23	0	0	possibly_damaging	0,78	neutral	0,76	neutral	2,74	neutral	-1,63	deleterious	-2,64	low_impact	1,15	neutral	0,76	neutral	0,57	deleterious	3,63	23,2	0,16	0,45	neutral	0,25	disease	0,57	neutral	0,33	neutral	0,44	1	neutral	0,74	deleterious	0,49	neutral	-3	deleterious	0,58	low_impact	-1,27	medium_impact	0,56	medium_impact	-0,18	0,56	0,8	24,21	35,91	N	0,28	N	0,74	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9062	9062	T	G	MI.1141	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	536	179	L	R	cTa/cGa	-0,33	0	0	possibly_damaging	0,82	neutral	0,23	neutral	4,34	deleterious	-3,83	deleterious	-4,2	medium_impact	2,7	neutral	0,81	neutral	0,32	deleterious	4,11	23,7	0,19	0,65	disease	0,8	disease	0,8	disease	0,59	disease	0,75	5	neutral	0,88	neutral	0,21	NA	0	deleterious	0,78	low_impact	-1,38	medium_impact	-0,01	medium_impact	1,22	0,71	0,9	44,25	7,93	N	0,29	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3619	3619	A	C	MI.11410	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	313	105	I	L	Att/Ctt	-3,23	0	0	benign	0,14	neutral	1	neutral	2,84	neutral	-0,44	neutral	-0,49	low_impact	0,82	neutral	0,88	neutral	0,91	deleterious	2,48	19,35	0,18	0,45	neutral	0,15	disease	0,51	neutral	0,29	neutral	0,44	1	neutral	0,13	deleterious	0,93	neutral	-6	neutral	0,16	medium_impact	-0,01	high_impact	1,96	medium_impact	-0,47	0,46	0,8	24,21	35,91	N	0,27	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3620	3620	T	G	MI.11411	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	314	105	I	S	aTt/aGt	0,22	0,01	0	possibly_damaging	0,56	neutral	0,4	neutral	2,62	neutral	-2,76	deleterious	-4,16	medium_impact	3,29	neutral	0,72	neutral	0,52	deleterious	4,07	23,7	0,04	0,35	neutral	0,43	disease	0,85	disease	0,57	disease	0,73	5	neutral	0,62	neutral	0,42	NA	0	deleterious	0,47	medium_impact	-0,85	medium_impact	0,18	medium_impact	1,69	0,28	0,8	24,21	35,91	N	0,38	N	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3620	3620	T	A	MI.11412	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	314	105	I	N	aTt/aAt	0,22	0,01	0	possibly_damaging	0,87	neutral	0,41	neutral	2,59	deleterious	-4,21	deleterious	-5,09	high_impact	3,98	neutral	0,73	neutral	0,49	deleterious	4,22	23,9	0,08	0,35	disease	0,61	disease	0,85	disease	0,59	disease	0,73	5	neutral	0,87	neutral	0,27	deleterious	1	deleterious	0,71	low_impact	-1,53	medium_impact	0,19	high_impact	2,29	0,29	0,8	24,21	35,91	N	0,4	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3620	3620	T	C	MI.11413	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	314	105	I	T	aTt/aCt	0,22	0,01	0	benign	0,06	neutral	0,32	neutral	2,64	neutral	-2,37	deleterious	-3,4	medium_impact	2,65	neutral	0,87	neutral	0,62	deleterious	3,16	22,6	0,09	0,35	neutral	0,37	disease	0,67	disease	0,57	disease	0,69	4	neutral	0,65	deleterious	0,63	neutral	-3	neutral	0,19	medium_impact	0,37	medium_impact	0,09	medium_impact	1,13	0,28	0,8	24,21	35,91	N	0,39	N	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3621	3621	T	G	MI.11414	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	315	105	I	M	atT/atG	5,5	0,86	0,01	benign	0,16	neutral	0,28	neutral	2,65	neutral	-2,44	neutral	-0,52	low_impact	1,17	neutral	0,8	neutral	0,95	neutral	1,73	14,61	0,19	0,45	neutral	0,3	neutral	0,38	neutral	0,35	neutral	0,45	1	neutral	0,67	deleterious	0,56	neutral	-6	neutral	0,18	medium_impact	-0,08	medium_impact	0,05	medium_impact	-0,17	0,54	0,8	24,21	35,91	N	0,5	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3621	3621	T	A	MI.11415	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	315	105	I	M	atT/atA	5,5	0,86	0,01	benign	0,16	neutral	0,28	neutral	2,65	neutral	-2,44	neutral	-0,52	low_impact	1,17	neutral	0,8	neutral	0,95	deleterious	2,09	16,79	0,19	0,45	neutral	0,3	neutral	0,38	neutral	0,35	neutral	0,45	1	neutral	0,67	deleterious	0,56	neutral	-6	neutral	0,18	medium_impact	-0,08	medium_impact	0,05	medium_impact	-0,17	0,54	0,8	24,21	35,91	N	0,5	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3622	3622	C	A	MI.11416	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	316	106	L	M	Cta/Ata	-4,84	0	0	probably_damaging	1	neutral	0,12	neutral	2,22	deleterious	-3,02	neutral	-1,69	medium_impact	2	neutral	0,71	damaging	0,15	deleterious	3,56	23,1	0,27	0,45	neutral	0,4	neutral	0,42	neutral	0,38	neutral	0,44	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	-0,21	medium_impact	0,56	0,56	0,8	59,12	10,61	N	0,34	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3622	3622	C	G	MI.11417	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	316	106	L	V	Cta/Gta	-4,84	0	0	probably_damaging	1	neutral	0,27	neutral	2,25	neutral	-2,62	neutral	-2,47	high_impact	3,6	neutral	0,67	damaging	0,08	deleterious	3,3	22,9	0,24	0,45	neutral	0,29	disease	0,58	disease	0,55	disease	0,54	1	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,72	low_impact	-3,57	medium_impact	0,03	medium_impact	1,96	0,54	0,8	59,12	10,61	N	0,32	N	0,84	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3623	3623	T	G	MI.11418	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	317	106	L	R	cTa/cGa	-0,7	0	0	probably_damaging	1	neutral	0,12	neutral	2,13	deleterious	-5,71	deleterious	-5,4	high_impact	4,64	damaging	0,52	damaging	0,05	deleterious	4,09	23,7	0,03	0,35	disease	0,59	disease	0,89	disease	0,74	disease	0,76	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	-0,21	high_impact	2,86	0,18	0,8	59,12	10,61	N	0,45	N	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3623	3623	T	C	MI.11419	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	317	106	L	P	cTa/cCa	-0,7	0	0	probably_damaging	1	neutral	0,09	neutral	2,13	deleterious	-6,24	deleterious	-6,26	high_impact	4,64	damaging	0,48	damaging	0,06	deleterious	3,8	23,4	0,03	0,35	neutral	0,47	disease	0,87	disease	0,74	disease	0,75	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	-0,29	high_impact	2,86	0,31	0,8	59,12	10,61	N	0,47	N	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9064	9064	G	A	MI.1142	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	538	180	A	T	Gca/Aca	-1,49	0	0	benign	0,03	neutral	0,45	neutral	4,44	neutral	0,58	neutral	-0,54	neutral_impact	0,03	neutral	0,93	neutral	0,92	deleterious	0,82	9,62	0,49	0,65	neutral	0,25	neutral	0,28	neutral	0,3	neutral	0,44	1	neutral	0,52	deleterious	0,71	neutral	-6	neutral	0,14	medium_impact	0,68	medium_impact	0,24	low_impact	-1,07	0,81	0,9	19,91	14,58	N	0,32	N	0,61	polymorphism	1	0,01	rs386420013	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3623	3623	T	A	MI.11420	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	317	106	L	Q	cTa/cAa	-0,7	0	0	probably_damaging	1	neutral	0,1	neutral	2,13	deleterious	-5,67	deleterious	-5,38	high_impact	4,64	damaging	0,56	damaging	0,06	deleterious	3,93	23,5	0,04	0,35	disease	0,61	disease	0,84	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	-0,26	high_impact	2,86	0,31	0,8	59,12	10,61	N	0,42	N	0,99	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3625	3625	G	A	MI.11421	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	319	107	A	T	Gcc/Acc	-0,47	0,49	0	probably_damaging	1	neutral	0,21	neutral	2,48	deleterious	-3,05	deleterious	-3,08	high_impact	3,56	neutral	0,8	damaging	0,23	deleterious	4,11	23,7	0,12	0,4	neutral	0,41	disease	0,76	neutral	0,41	neutral	0,49	0	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	-0,05	medium_impact	1,92	0,77	0,85	56,92	9,27	N	0,38	N	0,79	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3625	3625	G	C	MI.11422	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	319	107	A	P	Gcc/Ccc	-0,47	0,49	0	probably_damaging	1	neutral	0,09	neutral	2,42	deleterious	-5,13	deleterious	-4,21	high_impact	4,46	neutral	0,73	damaging	0,14	deleterious	3,71	23,3	0,03	0,35	disease	0,68	disease	0,93	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	-0,29	high_impact	2,71	0,6	0,8	56,92	9,27	N	0,49	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3625	3625	G	T	MI.11423	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	319	107	A	S	Gcc/Tcc	-0,47	0,49	0	probably_damaging	1	neutral	0,24	neutral	2,49	deleterious	-3,19	neutral	-2,08	medium_impact	2,11	neutral	0,84	neutral	0,69	deleterious	3,55	23,1	0,24	0,45	neutral	0,45	disease	0,79	neutral	0,39	neutral	0,5	0	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,79	low_impact	-3,57	medium_impact	-0,01	medium_impact	0,65	0,5	0,8	56,92	9,27	N	0,37	N	0,32	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3626	3626	C	A	MI.11424	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	320	107	A	D	gCc/gAc	3,9	1	0	probably_damaging	1	neutral	0,09	neutral	2,42	deleterious	-5,14	deleterious	-4,93	high_impact	4,46	neutral	0,79	damaging	0,09	deleterious	4,53	24,3	0,02	0,35	disease	0,71	disease	0,94	disease	0,7	disease	0,84	7	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,29	high_impact	2,71	0,34	0,8	56,92	9,27	P	0,58	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3626	3626	C	G	MI.11425	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	320	107	A	G	gCc/gGc	3,9	1	0	probably_damaging	1	neutral	0,44	neutral	2,48	neutral	-2,41	deleterious	-3,36	medium_impact	2,73	neutral	0,77	damaging	0,15	deleterious	3,88	23,5	0,22	0,45	disease	0,6	disease	0,81	neutral	0,4	disease	0,53	1	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,78	low_impact	-3,57	medium_impact	0,22	medium_impact	1,2	0,7	0,85	56,92	9,27	N	0,46	N	0,68	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3626	3626	C	T	MI.11426	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	320	107	A	V	gCc/gTc	3,9	1	0	probably_damaging	1	neutral	0,43	neutral	2,49	neutral	-2,26	deleterious	-3,5	medium_impact	2,54	neutral	0,7	damaging	0,1	deleterious	4,34	24	0,11	0,4	neutral	0,29	disease	0,85	disease	0,57	disease	0,64	3	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	0,21	medium_impact	1,03	0,75	0,85	56,92	9,27	N	0,48	N	0,82	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3628	3628	A	G	MI.11427	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	322	108	T	A	Acc/Gcc	-12,88	0	0	benign	0,01	neutral	0,18	neutral	2,83	neutral	0,51	neutral	-0,4	low_impact	0,86	neutral	0,84	neutral	0,85	deleterious	1,92	15,72	0,28	0,45	neutral	0,17	neutral	0,34	neutral	0,4	neutral	0,44	1	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,14	medium_impact	1,12	medium_impact	-0,09	medium_impact	-0,44	0,29	0,8	27,36	41,48	N	0,39	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3628	3628	A	T	MI.11428	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	322	108	T	S	Acc/Tcc	-12,88	0	0	benign	0,02	neutral	0,29	neutral	2,78	neutral	-0,7	neutral	-1,07	low_impact	1,4	neutral	0,69	neutral	0,69	deleterious	1,92	15,69	0,33	0,5	neutral	0,27	neutral	0,4	neutral	0,46	neutral	0,45	1	neutral	0,7	deleterious	0,64	neutral	-6	neutral	0,16	medium_impact	0,84	medium_impact	0,06	medium_impact	0,03	0,47	0,8	27,36	41,48	N	0,47	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3628	3628	A	C	MI.11429	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	322	108	T	P	Acc/Ccc	-12,88	0	0	possibly_damaging	0,55	neutral	0,06	neutral	2,74	neutral	-2,31	neutral	-2,1	medium_impact	1,96	neutral	0,6	neutral	0,45	deleterious	3,49	23,1	0,05	0,35	neutral	0,48	disease	0,83	disease	0,63	disease	0,78	6	neutral	0,94	neutral	0,26	NA	0	deleterious	0,68	medium_impact	-0,83	medium_impact	-0,4	medium_impact	0,52	0,32	0,8	27,36	41,48	N	0,34	N	0,61	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9064	9064	G	C	MI.1143	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	538	180	A	P	Gca/Cca	-1,49	0	0	possibly_damaging	0,83	neutral	0,19	neutral	4,3	neutral	-2,36	deleterious	-2,73	low_impact	1,68	neutral	0,76	neutral	0,35	deleterious	3,78	23,4	0,13	0,65	disease	0,81	disease	0,81	disease	0,63	disease	0,78	6	neutral	0,9	neutral	0,18	neutral	-3	deleterious	0,82	low_impact	-1,41	medium_impact	-0,06	medium_impact	0,34	0,88	0,9	19,91	14,58	N	0,24	N	0,97	polymorphism	1	0,05	rs386420013	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3629	3629	C	T	MI.11430	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	323	108	T	I	aCc/aTc	-0,24	0	0	benign	0,01	neutral	0,38	neutral	2,96	neutral	2,02	neutral	2,11	neutral_impact	-1,52	neutral	0,84	neutral	0,8	deleterious	0,85	9,78	0,1	0,4	neutral	0,14	neutral	0,32	neutral	0,26	neutral	0,43	1	neutral	0,61	deleterious	0,69	neutral	-6	neutral	0,13	medium_impact	1,12	medium_impact	0,16	low_impact	-2,52	0,43	0,8	27,36	41,48	N	0,32	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3629	3629	C	A	MI.11431	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	323	108	T	N	aCc/aAc	-0,24	0	0	benign	0,38	neutral	0,15	neutral	2,75	neutral	-1,94	neutral	-2,04	medium_impact	1,96	damaging	0,56	neutral	0,65	deleterious	3,2	22,7	0,24	0,45	neutral	0,44	disease	0,62	disease	0,51	disease	0,54	1	neutral	0,82	neutral	0,39	neutral	-3	neutral	0,41	medium_impact	-0,55	medium_impact	-0,15	medium_impact	0,52	0,47	0,8	27,36	41,48	N	0,39	N	0,5	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3629	3629	C	G	MI.11432	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	323	108	T	S	aCc/aGc	-0,24	0	0	benign	0,02	neutral	0,29	neutral	2,78	neutral	-0,7	neutral	-1,07	low_impact	1,4	neutral	0,69	neutral	0,69	neutral	1,62	13,97	0,33	0,5	neutral	0,27	neutral	0,4	neutral	0,46	neutral	0,45	1	neutral	0,7	deleterious	0,64	neutral	-6	neutral	0,16	medium_impact	0,84	medium_impact	0,06	medium_impact	0,03	0,47	0,8	27,36	41,48	N	0,48	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3631	3631	T	A	MI.11433	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	325	109	S	T	Tct/Act	-2,77	0	0	possibly_damaging	0,85	neutral	0,14	neutral	2,52	neutral	-1,85	deleterious	-2,77	medium_impact	2,42	neutral	0,66	damaging	0,13	deleterious	3,7	23,3	0,3	0,45	neutral	0,28	neutral	0,47	neutral	0,49	neutral	0,41	2	neutral	0,93	neutral	0,15	NA	0	deleterious	0,63	low_impact	-1,46	medium_impact	-0,17	medium_impact	0,93	0,49	0,8	56,29	9,64	N	0,39	N	0,6	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3631	3631	T	G	MI.11434	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	325	109	S	A	Tct/Gct	-2,77	0	0	possibly_damaging	0,64	neutral	0,19	neutral	2,54	neutral	-1,6	deleterious	-2,77	medium_impact	3	neutral	0,71	damaging	0,18	deleterious	3,6	23,2	0,28	0,45	neutral	0,26	disease	0,65	disease	0,63	disease	0,56	1	neutral	0,83	neutral	0,28	NA	0	deleterious	0,56	medium_impact	-0,99	medium_impact	-0,08	medium_impact	1,43	0,4	0,8	56,29	9,64	N	0,36	N	0,39	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3631	3631	T	C	MI.11435	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	325	109	S	P	Tct/Cct	-2,77	0	0	probably_damaging	0,98	neutral	0,05	neutral	2,41	deleterious	-4,03	deleterious	-4,63	high_impact	4,29	neutral	0,69	damaging	0,13	deleterious	3,87	23,5	0,05	0,35	disease	0,61	disease	0,9	disease	0,8	disease	0,78	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,84	low_impact	-2,34	medium_impact	-0,44	high_impact	2,56	0,31	0,8	56,29	9,64	N	0,5	N	0,94	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3632	3632	C	G	MI.11436	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	326	109	S	C	tCt/tGt	5,5	1	0	probably_damaging	0,98	neutral	0,25	neutral	2,4	deleterious	-4,7	deleterious	-4,63	high_impact	4,29	neutral	0,7	damaging	0,11	deleterious	3,51	23,1	0,08	0,35	disease	0,62	disease	0,85	disease	0,68	disease	0,72	4	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,78	low_impact	-2,34	medium_impact	0,01	high_impact	2,56	0,24	0,8	56,29	9,64	P	0,65	P	0,65	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3632	3632	C	A	MI.11437	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	326	109	S	Y	tCt/tAt	5,5	1	0	probably_damaging	0,97	neutral	0,29	neutral	2,41	deleterious	-4,34	deleterious	-5,55	high_impact	3,94	neutral	0,7	damaging	0,12	deleterious	3,93	23,5	0,06	0,35	neutral	0,49	disease	0,9	disease	0,72	disease	0,75	5	neutral	0,97	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-2,17	medium_impact	0,06	high_impact	2,25	0,2	0,8	56,29	9,64	P	0,63	P	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3632	3632	C	T	MI.11438	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	326	109	S	F	tCt/tTt	5,5	1	0	probably_damaging	0,92	neutral	0,73	neutral	2,41	deleterious	-4,09	deleterious	-5,55	medium_impact	3,44	neutral	0,61	damaging	0,11	deleterious	4,09	23,7	0,06	0,35	neutral	0,29	disease	0,92	disease	0,68	disease	0,74	5	neutral	0,9	neutral	0,41	deleterious	1	deleterious	0,73	low_impact	-1,75	medium_impact	0,52	medium_impact	1,82	0,16	0,8	56,29	9,64	N	0,47	N	0,93	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	C3632T	LHON (putative)	+	-	Reported	1
chrM	3634	3634	A	G	MI.11439	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	328	110	S	G	Agc/Ggc	-5,07	0	0	probably_damaging	1	neutral	0,19	neutral	2,31	neutral	-2,09	deleterious	-3,39	low_impact	1,82	neutral	0,8	neutral	0,76	deleterious	3,45	23	0,16	0,45	neutral	0,29	disease	0,58	disease	0,58	neutral	0,42	2	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,7	low_impact	-3,57	medium_impact	-0,08	medium_impact	0,4	0,39	0,8	16,35	25,33	N	0,34	N	0,24	polymorphism	1	0,21	rs878880889	.	.	.	.	.	.	.	.	A3634G	LHON	+	-	Reported	1
chrM	9064	9064	G	T	MI.1144	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	538	180	A	S	Gca/Tca	-1,49	0	0	benign	0,39	neutral	0,8	neutral	4,41	neutral	0,17	neutral	-1,37	neutral_impact	0,03	neutral	0,85	neutral	0,67	deleterious	2,04	16,46	0,48	0,65	neutral	0,38	neutral	0,36	neutral	0,31	neutral	0,47	1	neutral	0,27	deleterious	0,71	neutral	-6	neutral	0,37	medium_impact	-0,57	medium_impact	0,63	low_impact	-1,07	0,87	0,9	19,91	14,58	N	0,23	N	0,5	polymorphism	1	0,02	rs386420013	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3634	3634	A	T	MI.11440	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	328	110	S	C	Agc/Tgc	-5,07	0	0	probably_damaging	1	neutral	0,22	neutral	2,13	deleterious	-5,55	deleterious	-4,57	high_impact	4,41	neutral	0,7	neutral	0,39	deleterious	3,42	23	0,08	0,35	disease	0,54	disease	0,84	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	-0,03	high_impact	2,66	0,24	0,8	16,35	25,33	N	0,51	P	0,59	polymorphism	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3634	3634	A	C	MI.11441	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	328	110	S	R	Agc/Cgc	-5,07	0	0	probably_damaging	1	neutral	0,11	neutral	2,15	deleterious	-4,61	deleterious	-4,53	high_impact	4,76	neutral	0,7	neutral	0,37	deleterious	3,8	23,4	0,04	0,35	disease	0,64	disease	0,9	disease	0,8	disease	0,78	6	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	-0,23	high_impact	2,97	0,32	0,8	16,35	25,33	P	0,74	P	0,96	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3635	3635	G	C	MI.11442	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	329	110	S	T	aGc/aCc	5,5	1	0,01	probably_damaging	1	neutral	0,12	neutral	2,2	deleterious	-3,37	deleterious	-2,74	medium_impact	2,92	neutral	0,63	neutral	0,41	deleterious	3,27	22,8	0,24	0,45	neutral	0,38	disease	0,67	disease	0,67	disease	0,65	3	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	-0,21	medium_impact	1,36	0,36	0,8	16,35	25,33	P	0,62	P	0,66	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3635	3635	G	A	MI.11443	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	329	110	S	N	aGc/aAc	5,5	1	0,01	probably_damaging	1	neutral	0,19	neutral	2,16	deleterious	-4,17	deleterious	-2,68	high_impact	4,41	neutral	0,66	neutral	0,45	deleterious	3,52	23,1	0,29	0,45	disease	0,62	disease	0,81	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	-0,08	high_impact	2,66	0,31	0,8	16,35	25,33	P	0,75	P	0,6	disease_causing_automatic	0	0,44	rs397515507	Pathogenic	Leber's_optic_atrophy	RCV000055707.1	MedGen:OMIM:SNOMED_CT	.	.	.	.	G3635A	LHON	+	-	Cfrm	8
chrM	3635	3635	G	T	MI.11444	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	329	110	S	I	aGc/aTc	5,5	1	0,01	probably_damaging	1	neutral	0,36	neutral	2,14	deleterious	-5,15	deleterious	-5,49	high_impact	4,76	neutral	0,69	neutral	0,51	deleterious	4,04	23,7	0,05	0,35	disease	0,51	disease	0,92	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,14	high_impact	2,97	0,23	0,8	16,35	25,33	P	0,74	P	0,98	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3637	3637	C	A	MI.11445	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	331	111	L	M	Cta/Ata	-0,24	0	0	probably_damaging	1	neutral	0,18	neutral	2,15	deleterious	-3,61	neutral	-1,16	low_impact	0,96	neutral	0,73	neutral	0,58	deleterious	2,51	19,54	0,28	0,45	neutral	0,45	neutral	0,22	neutral	0,35	neutral	0,38	2	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,7	low_impact	-3,57	medium_impact	-0,09	medium_impact	-0,35	0,54	0,8	60,06	9,93	N	0,43	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3637	3637	C	G	MI.11446	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	331	111	L	V	Cta/Gta	-0,24	0	0	probably_damaging	1	neutral	0,24	neutral	2,28	neutral	-2,1	neutral	-2,29	medium_impact	2,33	neutral	0,7	neutral	0,44	deleterious	3,36	22,9	0,27	0,45	neutral	0,25	disease	0,57	disease	0,55	disease	0,54	1	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	-0,01	medium_impact	0,85	0,49	0,8	60,06	9,93	N	0,38	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3638	3638	T	C	MI.11447	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	332	111	L	P	cTa/cCa	-0,93	0	0	probably_damaging	1	deleterious	0,04	neutral	2,09	deleterious	-6,32	deleterious	-5,86	high_impact	3,86	neutral	0,67	neutral	0,33	deleterious	3,86	23,5	0,04	0,35	disease	0,88	disease	0,86	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,88	low_impact	-3,57	medium_impact	-0,5	high_impact	2,18	0,18	0,8	60,06	9,93	N	0,4	N	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3638	3638	T	G	MI.11448	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	332	111	L	R	cTa/cGa	-0,93	0	0	probably_damaging	1	neutral	0,08	neutral	2,09	deleterious	-5,78	deleterious	-4,98	high_impact	4,41	neutral	0,68	neutral	0,31	deleterious	4,13	23,8	0,04	0,35	disease	0,85	disease	0,88	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	-0,32	high_impact	2,66	0,1	0,8	60,06	9,93	N	0,52	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3638	3638	T	A	MI.11449	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	332	111	L	Q	cTa/cAa	-0,93	0	0	probably_damaging	1	neutral	0,06	neutral	2,09	deleterious	-5,75	deleterious	-4,87	high_impact	3,86	neutral	0,73	neutral	0,34	deleterious	4,02	23,6	0,06	0,35	disease	0,85	disease	0,78	disease	0,64	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	-0,4	high_impact	2,18	0,2	0,8	60,06	9,93	N	0,4	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9065	9065	C	G	MI.1145	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	539	180	A	G	gCa/gGa	0,36	0	0	possibly_damaging	0,47	neutral	0,33	neutral	4,31	neutral	-1,81	deleterious	-2,78	low_impact	0,81	neutral	0,85	neutral	0,62	deleterious	2,31	18,25	0,32	0,65	disease	0,75	neutral	0,48	neutral	0,45	disease	0,62	2	neutral	0,64	neutral	0,43	neutral	-3	deleterious	0,5	medium_impact	-0,71	medium_impact	0,12	medium_impact	-0,4	0,82	0,9	19,91	14,58	N	0,33	N	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3640	3640	G	T	MI.11450	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	334	112	A	S	Gcc/Tcc	-1,85	0	0	benign	0,08	neutral	0,65	neutral	2,77	neutral	-0,5	neutral	-1,42	neutral_impact	0,27	neutral	0,82	neutral	0,89	deleterious	0,48	7,25	0,31	0,45	neutral	0,21	neutral	0,45	neutral	0,25	neutral	0,45	1	neutral	0,26	deleterious	0,79	neutral	-6	neutral	0,16	medium_impact	0,25	medium_impact	0,43	medium_impact	-0,95	0,41	0,8	29,87	28,44	N	0,3	N	0,05	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3640	3640	G	C	MI.11451	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	334	112	A	P	Gcc/Ccc	-1,85	0	0	possibly_damaging	0,86	neutral	0,16	neutral	2,61	neutral	-1,94	deleterious	-3,41	medium_impact	3,35	neutral	0,68	neutral	0,34	deleterious	1,98	16,09	0,06	0,35	disease	0,53	disease	0,9	disease	0,62	disease	0,74	5	neutral	0,93	neutral	0,15	NA	0	deleterious	0,71	low_impact	-1,49	medium_impact	-0,13	medium_impact	1,74	0,39	0,8	29,87	28,44	N	0,42	N	0,74	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3640	3640	G	A	MI.11452	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	334	112	A	T	Gcc/Acc	-1,85	0	0	benign	0,03	neutral	0,33	neutral	2,68	neutral	-1,66	neutral	-1,65	neutral_impact	0,26	neutral	0,81	neutral	0,79	deleterious	0,84	9,73	0,18	0,45	neutral	0,25	neutral	0,37	neutral	0,31	neutral	0,45	1	neutral	0,65	deleterious	0,65	neutral	-6	neutral	0,14	medium_impact	0,67	medium_impact	0,1	medium_impact	-0,96	0,59	0,8	29,87	28,44	N	0,4	N	0,04	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3641	3641	C	A	MI.11453	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	335	112	A	D	gCc/gAc	-0,01	0	0	possibly_damaging	0,73	neutral	0,16	neutral	2,64	neutral	-2,32	deleterious	-4,01	medium_impact	3	neutral	0,74	neutral	0,36	deleterious	2,66	20,5	0,04	0,35	neutral	0,37	disease	0,89	disease	0,67	disease	0,75	5	neutral	0,88	neutral	0,22	NA	0	deleterious	0,6	low_impact	-1,16	medium_impact	-0,13	medium_impact	1,43	0,26	0,8	29,87	28,44	N	0,4	N	0,61	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3641	3641	C	T	MI.11454	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	335	112	A	V	gCc/gTc	-0,01	0	0	benign	0,18	neutral	0,54	neutral	2,68	neutral	-1,82	neutral	-2,44	medium_impact	2,46	neutral	0,7	neutral	0,51	deleterious	2,43	19,04	0,17	0,45	neutral	0,32	disease	0,72	disease	0,55	disease	0,66	3	neutral	0,35	deleterious	0,68	neutral	-3	neutral	0,22	medium_impact	-0,13	medium_impact	0,31	medium_impact	0,96	0,57	0,8	29,87	28,44	N	0,3	N	0,42	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3641	3641	C	G	MI.11455	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	335	112	A	G	gCc/gGc	-0,01	0	0	possibly_damaging	0,52	neutral	0,38	neutral	2,68	neutral	-0,01	deleterious	-2,94	neutral_impact	0,61	neutral	0,85	neutral	0,63	deleterious	1,95	15,88	0,29	0,45	neutral	0,18	neutral	0,33	neutral	0,26	neutral	0,45	1	neutral	0,61	neutral	0,43	neutral	-3	neutral	0,26	medium_impact	-0,78	medium_impact	0,16	medium_impact	-0,66	0,65	0,8	29,87	28,44	N	0,3	N	0,32	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3643	3643	G	C	MI.11456	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	337	113	V	L	Gtt/Ctt	-4,38	0	0	possibly_damaging	0,73	neutral	1	neutral	2,32	neutral	-2,72	deleterious	-2,68	high_impact	3,81	neutral	0,72	neutral	0,59	deleterious	3,58	23,2	0,27	0,45	neutral	0,32	disease	0,82	disease	0,59	disease	0,67	3	neutral	0,73	deleterious	0,64	deleterious	1	deleterious	0,65	low_impact	-1,16	high_impact	1,96	high_impact	2,14	0,49	0,8	56,6	9,69	N	0,38	N	0,71	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3643	3643	G	A	MI.11457	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	337	113	V	I	Gtt/Att	-4,38	0	0	possibly_damaging	0,79	neutral	0,48	neutral	2,34	neutral	-2,55	neutral	-0,92	medium_impact	3	neutral	0,73	neutral	0,68	deleterious	3,52	23,1	0,33	0,5	neutral	0,31	disease	0,69	disease	0,56	disease	0,57	1	neutral	0,77	neutral	0,35	NA	0	deleterious	0,66	low_impact	-1,29	medium_impact	0,26	medium_impact	1,43	0,62	0,8	56,6	9,69	N	0,45	N	0,39	polymorphism	1	0,06	.	.	.	.	.	.	COSM1155619	.	.	.	.	.	.	.	.
chrM	3643	3643	G	T	MI.11458	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	337	113	V	F	Gtt/Ttt	-4,38	0	0	probably_damaging	0,98	neutral	0,71	neutral	2,25	deleterious	-4,42	deleterious	-4,48	high_impact	4,44	neutral	0,68	neutral	0,55	deleterious	3,81	23,4	0,05	0,35	disease	0,51	disease	0,93	disease	0,65	disease	0,75	5	neutral	0,97	neutral	0,37	deleterious	2	deleterious	0,82	low_impact	-2,34	medium_impact	0,49	high_impact	2,69	0,34	0,8	56,6	9,69	N	0,44	N	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3644	3644	T	G	MI.11459	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	338	113	V	G	gTt/gGt	7,11	1	0,04	possibly_damaging	0,88	neutral	0,28	neutral	2,26	deleterious	-4,12	deleterious	-6,15	medium_impact	3,02	neutral	0,7	neutral	0,65	deleterious	3,7	23,3	0,04	0,35	disease	0,54	disease	0,84	disease	0,64	disease	0,7	4	neutral	0,91	neutral	0,2	NA	0	deleterious	0,73	low_impact	-1,56	medium_impact	0,05	medium_impact	1,45	0,2	0,8	56,6	9,69	P	0,6	P	0,95	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9065	9065	C	T	MI.1146	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	539	180	A	V	gCa/gTa	0,36	0	0	benign	0,39	neutral	0,91	neutral	4,48	neutral	0,88	neutral	-1	neutral_impact	-0,37	neutral	0,94	neutral	0,96	deleterious	0,1	3,56	0,48	0,65	neutral	0,41	neutral	0,18	neutral	0,29	neutral	0,25	5	neutral	0,3	deleterious	0,76	neutral	-6	neutral	0,41	medium_impact	-0,57	medium_impact	0,86	low_impact	-1,42	0,81	0,9	19,91	14,58	N	0,24	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3644	3644	T	A	MI.11460	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	338	113	V	D	gTt/gAt	7,11	1	0,04	probably_damaging	0,98	neutral	0,13	neutral	2,25	deleterious	-4,67	deleterious	-6,23	high_impact	4,79	neutral	0,73	neutral	0,57	deleterious	4,33	24	0,03	0,35	disease	0,56	disease	0,91	disease	0,76	disease	0,76	5	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,82	low_impact	-2,34	medium_impact	-0,19	high_impact	3	0,06	0,8	56,6	9,69	P	0,71	P	0,99	polymorphism	0,99	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3644	3644	T	C	MI.11461	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	338	113	V	A	gTt/gCt	7,11	1	0,04	benign	0,12	neutral	0,63	neutral	2,32	neutral	-2,79	deleterious	-3,33	medium_impact	3,21	neutral	0,65	neutral	0,72	deleterious	3,33	22,9	0,13	0,4	neutral	0,29	disease	0,66	disease	0,56	disease	0,55	1	neutral	0,27	deleterious	0,76	neutral	-3	neutral	0,23	medium_impact	0,06	medium_impact	0,4	medium_impact	1,62	0,09	0,8	56,6	9,69	P	0,63	P	0,64	polymorphism	1	0,19	rs878991470	.	.	.	.	.	.	CPD	0,45	T3644C	BD-associated	.	.	Reported	3
chrM	3646	3646	T	A	MI.11462	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	340	114	Y	N	Tac/Aac	-20	0	0	possibly_damaging	0,89	neutral	0,31	neutral	2,33	deleterious	-4,47	deleterious	-8,23	high_impact	4,5	neutral	0,72	damaging	0,12	deleterious	3,92	23,5	0,06	0,35	disease	0,75	disease	0,8	disease	0,72	disease	0,67	3	neutral	0,91	neutral	0,21	deleterious	1	deleterious	0,75	low_impact	-1,6	medium_impact	0,08	high_impact	2,74	0,2	0,8	51,89	8,86	N	0,46	N	0,95	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3646	3646	T	C	MI.11463	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	340	114	Y	H	Tac/Cac	-20	0	0	benign	0,12	neutral	0,53	neutral	2,33	deleterious	-4,38	deleterious	-4,57	medium_impact	3,4	neutral	0,75	damaging	0,25	deleterious	3,42	23	0,14	0,4	disease	0,7	disease	0,73	disease	0,78	disease	0,67	3	neutral	0,38	deleterious	0,71	neutral	-3	neutral	0,3	medium_impact	0,06	medium_impact	0,3	medium_impact	1,78	0,26	0,8	51,89	8,86	N	0,27	N	0,48	polymorphism	1	0,27	rs879122447	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3646	3646	T	G	MI.11464	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	340	114	Y	D	Tac/Gac	-20	0	0	probably_damaging	0,96	neutral	0,2	neutral	2,32	deleterious	-5	deleterious	-9,15	high_impact	4,85	neutral	0,76	damaging	0,09	deleterious	3,85	23,4	0,03	0,35	disease	0,84	disease	0,85	disease	0,82	disease	0,77	5	neutral	0,97	neutral	0,12	deleterious	2	deleterious	0,81	low_impact	-2,05	medium_impact	-0,06	high_impact	3,05	0,17	0,8	51,89	8,86	P	0,61	P	0,99	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3647	3647	A	C	MI.11465	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	341	114	Y	S	tAc/tCc	3,67	1	0	probably_damaging	0,92	neutral	0,43	neutral	2,35	deleterious	-3,7	deleterious	-8,2	high_impact	4,85	neutral	0,72	damaging	0,11	deleterious	3,65	23,2	0,06	0,35	disease	0,63	disease	0,81	disease	0,74	disease	0,73	5	neutral	0,92	neutral	0,26	deleterious	2	deleterious	0,78	low_impact	-1,75	medium_impact	0,21	high_impact	3,05	0,2	0,8	51,89	8,86	P	0,69	P	0,92	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3647	3647	A	T	MI.11466	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	341	114	Y	F	tAc/tTc	3,67	1	0	possibly_damaging	0,85	neutral	0,7	neutral	2,42	neutral	-2,38	deleterious	-3,66	medium_impact	2,75	neutral	0,66	damaging	0,1	deleterious	3,34	22,9	0,24	0,45	neutral	0,17	disease	0,78	disease	0,68	disease	0,61	2	neutral	0,82	neutral	0,43	NA	0	deleterious	0,65	low_impact	-1,46	medium_impact	0,48	medium_impact	1,21	0,46	0,8	51,89	8,86	N	0,49	N	0,72	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3647	3647	A	G	MI.11467	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	341	114	Y	C	tAc/tGc	3,67	1	0	probably_damaging	0,98	neutral	0,18	neutral	2,32	deleterious	-5,33	deleterious	-8,25	high_impact	4,85	neutral	0,74	damaging	0,07	deleterious	3,5	23,1	0,05	0,35	disease	0,79	disease	0,83	disease	0,78	disease	0,76	5	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-2,34	medium_impact	-0,09	high_impact	3,05	0,1	0,8	51,89	8,86	P	0,68	P	0,99	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3649	3649	T	G	MI.11468	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	343	115	S	A	Tca/Gca	-0,7	0,11	0	probably_damaging	1	neutral	0,51	neutral	2,78	neutral	-0,21	neutral	-2,14	low_impact	1,07	neutral	0,9	neutral	0,9	deleterious	2,5	19,44	0,28	0,45	neutral	0,18	neutral	0,35	neutral	0,36	neutral	0,43	1	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,68	low_impact	-3,57	medium_impact	0,29	medium_impact	-0,25	0,57	0,8	56,29	9,66	N	0,38	N	0,46	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3649	3649	T	C	MI.11469	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	343	115	S	P	Tca/Cca	-0,7	0,11	0	probably_damaging	1	neutral	0,2	neutral	2,61	neutral	-2,92	deleterious	-4,03	medium_impact	2,13	neutral	0,72	damaging	0,15	deleterious	3,97	23,6	0,03	0,35	neutral	0,43	disease	0,86	disease	0,52	disease	0,6	2	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,8	low_impact	-3,57	medium_impact	-0,06	medium_impact	0,67	0,4	0,8	56,29	9,66	N	0,35	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9065	9065	C	A	MI.1147	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	539	180	A	E	gCa/gAa	0,36	0	0	possibly_damaging	0,71	neutral	0,25	neutral	4,33	neutral	-1,18	deleterious	-2,77	low_impact	1,34	neutral	0,88	neutral	0,62	deleterious	3,14	22,6	0,21	0,65	disease	0,64	disease	0,75	disease	0,61	disease	0,6	2	neutral	0,81	neutral	0,27	neutral	-3	deleterious	0,66	low_impact	-1,13	medium_impact	0,02	medium_impact	0,05	0,77	0,9	19,91	14,58	N	0,31	N	0,94	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3649	3649	T	A	MI.11470	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	343	115	S	T	Tca/Aca	-0,7	0,11	0	probably_damaging	1	neutral	0,4	neutral	2,8	neutral	-0,03	neutral	-1,85	neutral_impact	0,21	neutral	0,87	neutral	0,89	deleterious	2,72	20,9	0,26	0,45	neutral	0,21	neutral	0,24	neutral	0,29	neutral	0,42	2	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,68	low_impact	-3,57	medium_impact	0,18	low_impact	-1,01	0,68	0,85	56,29	9,66	N	0,42	N	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3650	3650	C	T	MI.11471	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	344	115	S	L	tCa/tTa	3,44	1	0	probably_damaging	1	neutral	0,67	neutral	2,62	neutral	-2,46	deleterious	-4,79	medium_impact	2,48	neutral	0,71	damaging	0,12	deleterious	4,58	24,4	0,08	0,35	neutral	0,3	disease	0,84	disease	0,56	disease	0,68	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	0,45	medium_impact	0,98	0,54	0,8	56,29	9,66	N	0,4	N	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3650	3650	C	G	MI.11472	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	344	115	S	W	tCa/tGa	3,44	1	0	probably_damaging	1	neutral	0,18	neutral	2,58	deleterious	-5,73	deleterious	-5,77	medium_impact	3,25	neutral	0,72	damaging	0,11	deleterious	4,29	24	0,05	0,35	disease	0,78	disease	0,88	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,82	low_impact	-3,57	medium_impact	-0,09	medium_impact	1,65	0,23	0,8	56,29	9,66	N	0,47	N	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3652	3652	A	C	MI.11473	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	346	116	I	L	Atc/Ctc	-20	0	0	possibly_damaging	0,64	neutral	0,65	neutral	2,8	neutral	-0,01	neutral	-1,77	medium_impact	2,04	neutral	0,81	neutral	0,53	deleterious	3,67	23,3	0,28	0,45	neutral	0,18	neutral	0,44	neutral	0,34	neutral	0,4	2	neutral	0,58	deleterious	0,51	NA	0	neutral	0,38	medium_impact	-0,99	medium_impact	0,43	medium_impact	0,59	0,65	0,8	60,06	9,79	N	0,33	N	0,82	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3652	3652	A	G	MI.11474	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	346	116	I	V	Atc/Gtc	-20	0	0	possibly_damaging	0,64	neutral	0,5	neutral	2,85	neutral	0,19	neutral	-0,85	low_impact	1,9	neutral	0,75	neutral	0,58	deleterious	2,89	21,8	0,33	0,5	neutral	0,19	neutral	0,12	neutral	0,36	neutral	0,27	5	neutral	0,62	neutral	0,43	neutral	-3	neutral	0,29	medium_impact	-0,99	medium_impact	0,28	medium_impact	0,47	0,44	0,8	60,06	9,79	N	0,4	N	0,73	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3652	3652	A	T	MI.11475	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	346	116	I	F	Atc/Ttc	-20	0	0	probably_damaging	0,97	neutral	0,7	neutral	2,55	neutral	-2,46	deleterious	-3,58	medium_impact	2,6	neutral	0,72	neutral	0,36	deleterious	3,81	23,4	0,14	0,4	neutral	0,29	disease	0,74	disease	0,54	disease	0,61	2	neutral	0,96	neutral	0,37	deleterious	1	deleterious	0,68	low_impact	-2,17	medium_impact	0,48	medium_impact	1,08	0,62	0,8	60,06	9,79	N	0,29	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3653	3653	T	A	MI.11476	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	347	116	I	N	aTc/aAc	2,98	0,98	0	probably_damaging	0,94	neutral	0,3	neutral	2,51	deleterious	-4,14	deleterious	-6,21	high_impact	4,43	neutral	0,75	neutral	0,45	deleterious	4,55	24,3	0,06	0,35	neutral	0,44	disease	0,78	disease	0,62	disease	0,67	3	neutral	0,95	neutral	0,18	deleterious	2	deleterious	0,69	low_impact	-1,87	medium_impact	0,07	high_impact	2,68	0,33	0,8	60,06	9,79	P	0,62	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3653	3653	T	G	MI.11477	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	347	116	I	S	aTc/aGc	2,98	0,98	0	possibly_damaging	0,83	neutral	0,41	neutral	2,53	deleterious	-3,08	deleterious	-5,27	high_impact	3,63	neutral	0,74	neutral	0,53	deleterious	4,22	23,9	0,04	0,35	neutral	0,35	disease	0,77	disease	0,6	disease	0,66	3	neutral	0,83	neutral	0,29	deleterious	1	deleterious	0,58	low_impact	-1,4	medium_impact	0,19	medium_impact	1,98	0,31	0,8	60,06	9,79	P	0,57	P	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3653	3653	T	C	MI.11478	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	347	116	I	T	aTc/aCc	2,98	0,98	0	benign	0,12	neutral	0,39	neutral	2,59	neutral	-1,78	deleterious	-4,32	low_impact	1,66	neutral	0,78	neutral	0,56	deleterious	3,37	22,9	0,08	0,35	neutral	0,25	neutral	0,49	neutral	0,43	neutral	0,43	1	neutral	0,55	deleterious	0,64	neutral	-6	neutral	0,15	medium_impact	0,06	medium_impact	0,17	medium_impact	0,26	0,35	0,8	60,06	9,79	N	0,51	P	0,96	polymorphism	1	0,13	.	.	.	.	.	MNGIE fibroblasts	.	.	.	.	.	.	.	.	.
chrM	3654	3654	C	A	MI.11479	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	348	116	I	M	atC/atA	7,34	1	0	probably_damaging	0,97	neutral	0,22	neutral	2,55	neutral	-2,62	deleterious	-2,65	medium_impact	2,96	neutral	0,73	neutral	0,47	deleterious	3,85	23,4	0,22	0,45	neutral	0,34	neutral	0,47	disease	0,52	neutral	0,47	1	neutral	0,98	neutral	0,13	deleterious	1	deleterious	0,65	low_impact	-2,17	medium_impact	-0,03	medium_impact	1,4	0,54	0,8	60,06	9,79	P	0,67	P	0,74	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9067	9067	A	T	MI.1148	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	541	181	M	L	Ata/Tta	-11,9	0	0	benign	0	neutral	1	neutral	4,08	neutral	1,11	neutral	1,22	neutral_impact	-1,58	neutral	0,79	neutral	0,95	neutral	-1,03	0,01	0,52	0,65	neutral	0,29	neutral	0,16	neutral	0,37	neutral	0,24	5	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,09	high_impact	1,98	low_impact	-2,45	0,57	0,9	45,13	8,06	N	0,29	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3654	3654	C	G	MI.11480	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	348	116	I	M	atC/atG	7,34	1	0	probably_damaging	0,97	neutral	0,22	neutral	2,55	neutral	-2,62	deleterious	-2,65	medium_impact	2,96	neutral	0,73	neutral	0,47	deleterious	3,39	23	0,22	0,45	neutral	0,34	neutral	0,47	disease	0,52	neutral	0,47	1	neutral	0,98	neutral	0,13	deleterious	1	deleterious	0,65	low_impact	-2,17	medium_impact	-0,03	medium_impact	1,4	0,54	0,8	60,06	9,79	P	0,67	P	0,74	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3655	3655	C	G	MI.11481	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	349	117	L	V	Ctc/Gtc	-5,3	0	0	probably_damaging	1	neutral	0,63	neutral	2,17	neutral	-2,74	deleterious	-2,69	medium_impact	2,68	neutral	0,68	damaging	0,1	deleterious	3,38	22,9	0,29	0,45	neutral	0,29	neutral	0,5	disease	0,55	disease	0,6	2	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,69	low_impact	-3,57	medium_impact	0,4	medium_impact	1,15	0,66	0,8	60,06	10,09	N	0,21	N	0,84	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3655	3655	C	A	MI.11482	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	349	117	L	I	Ctc/Atc	-5,3	0	0	probably_damaging	1	neutral	0,45	neutral	2,28	neutral	-1,91	neutral	-1,8	medium_impact	2,26	neutral	0,78	damaging	0,13	deleterious	4,03	23,7	0,29	0,45	neutral	0,26	disease	0,54	neutral	0,38	neutral	0,37	3	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,23	medium_impact	0,79	0,55	0,8	60,06	10,09	N	0,24	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3655	3655	C	T	MI.11483	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	349	117	L	F	Ctc/Ttc	-5,3	0	0	probably_damaging	1	neutral	0,64	neutral	2,09	deleterious	-4	deleterious	-3,61	medium_impact	2,56	neutral	0,69	damaging	0,09	deleterious	3,93	23,5	0,19	0,45	neutral	0,4	disease	0,69	disease	0,64	disease	0,6	2	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	0,42	medium_impact	1,05	0,61	0,8	60,06	10,09	N	0,19	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3656	3656	T	A	MI.11484	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	350	117	L	H	cTc/cAc	-0,01	0	0	probably_damaging	1	neutral	0,42	neutral	2,04	deleterious	-6,82	deleterious	-6,32	high_impact	4,55	neutral	0,73	damaging	0,08	deleterious	4,07	23,7	0,03	0,35	disease	0,78	disease	0,74	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,2	high_impact	2,79	0,36	0,8	60,06	10,09	N	0,41	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3656	3656	T	C	MI.11485	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	350	117	L	P	cTc/cCc	-0,01	0	0	probably_damaging	1	neutral	0,21	neutral	2,04	deleterious	-6,58	deleterious	-6,28	high_impact	4,55	neutral	0,78	damaging	0,08	deleterious	3,83	23,4	0,01	0,35	disease	0,77	disease	0,8	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,05	high_impact	2,79	0,41	0,8	60,06	10,09	N	0,43	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3656	3656	T	G	MI.11486	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	350	117	L	R	cTc/cGc	-0,01	0	0	probably_damaging	1	neutral	0,27	neutral	2,04	deleterious	-6,01	deleterious	-5,41	high_impact	4,55	neutral	0,76	damaging	0,08	deleterious	4,15	23,8	0,01	0,35	disease	0,71	disease	0,79	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	0,03	high_impact	2,79	0,29	0,8	60,06	10,09	N	0,47	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3658	3658	T	C	MI.11487	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	352	118	W	R	Tga/Cga	-2,08	0	0	probably_damaging	1	neutral	0,18	neutral	2,8	neutral	0,41	deleterious	-6,41	medium_impact	3,34	neutral	0,67	damaging	0,07	deleterious	3,49	23,1	0,05	0,35	neutral	0,34	disease	0,76	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	-0,09	medium_impact	1,73	0,28	0,8	59,75	10,45	N	0,32	N	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3658	3658	T	G	MI.11488	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	352	118	W	G	Tga/Gga	-2,08	0	0	probably_damaging	1	neutral	0,29	neutral	2,84	neutral	1,26	deleterious	-2,88	neutral_impact	0,33	neutral	0,83	neutral	0,35	neutral	1,11	11,28	0,08	0,35	neutral	0,25	neutral	0,21	disease	0,59	neutral	0,39	2	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,67	low_impact	-3,57	medium_impact	0,06	medium_impact	-0,9	0,23	0,8	59,75	10,45	N	0,3	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3659	3659	G	T	MI.11489	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	353	118	W	L	tGa/tTa	4,81	1	0	probably_damaging	1	neutral	0,92	neutral	2,95	neutral	4,87	deleterious	-6,7	neutral_impact	0,67	neutral	0,74	damaging	0,08	deleterious	4,2	23,9	0,1	0,4	neutral	0,21	disease	0,65	neutral	0,5	neutral	0,38	2	deleterious	1	neutral	0,46	neutral	-2	deleterious	0,68	low_impact	-3,57	medium_impact	0,87	medium_impact	-0,6	0,12	0,8	59,75	10,45	N	0,38	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9067	9067	A	C	MI.1149	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	541	181	M	L	Ata/Cta	-11,9	0	0	benign	0	neutral	1	neutral	4,08	neutral	1,11	neutral	1,22	neutral_impact	-1,58	neutral	0,79	neutral	0,95	neutral	-1,18	0,01	0,52	0,65	neutral	0,29	neutral	0,16	neutral	0,37	neutral	0,24	5	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,09	high_impact	1,98	low_impact	-2,45	0,57	0,9	45,13	8,06	N	0,29	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3659	3659	G	C	MI.11490	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	353	118	W	S	tGa/tCa	4,81	1	0	probably_damaging	1	neutral	0,69	neutral	2,83	neutral	1,38	deleterious	-5,49	medium_impact	2,44	neutral	0,76	damaging	0,12	deleterious	2,78	21,3	0,08	0,35	neutral	0,22	disease	0,76	disease	0,6	disease	0,63	3	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,47	medium_impact	0,94	0,24	0,8	59,75	10,45	N	0,4	N	0,99	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3660	3660	A	C	MI.11491	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	354	118	W	C	tgA/tgC	8,95	1	0	probably_damaging	1	neutral	0,15	neutral	2,79	neutral	0,06	deleterious	-6,28	medium_impact	2,02	neutral	0,69	damaging	0,07	deleterious	3,96	23,6	0,09	0,35	neutral	0,39	disease	0,84	disease	0,58	disease	0,71	4	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	-0,15	medium_impact	0,58	0,26	0,8	59,75	10,45	N	0,46	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3660	3660	A	T	MI.11492	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	354	118	W	C	tgA/tgT	8,95	1	0	probably_damaging	1	neutral	0,15	neutral	2,79	neutral	0,06	deleterious	-6,28	medium_impact	2,02	neutral	0,69	damaging	0,07	deleterious	4,05	23,7	0,09	0,35	neutral	0,39	disease	0,84	disease	0,58	disease	0,71	4	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	-0,15	medium_impact	0,58	0,26	0,8	59,75	10,45	N	0,46	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3661	3661	T	C	MI.11493	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	355	119	S	P	Tca/Cca	-0,01	0,96	0	probably_damaging	1	neutral	0,16	neutral	2,42	deleterious	-3,9	deleterious	-4,47	high_impact	4,34	neutral	0,71	damaging	0,16	deleterious	3,93	23,5	0,04	0,35	disease	0,58	disease	0,87	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	-0,13	high_impact	2,6	0,37	0,8	59,75	10,41	P	0,58	P	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3661	3661	T	G	MI.11494	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	355	119	S	A	Tca/Gca	-0,01	0,96	0	probably_damaging	1	neutral	0,53	neutral	2,79	neutral	-0,06	deleterious	-2,56	low_impact	1,2	neutral	0,83	damaging	0,28	deleterious	3,62	23,2	0,27	0,45	neutral	0,14	neutral	0,26	neutral	0,43	neutral	0,38	2	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,67	low_impact	-3,57	medium_impact	0,3	medium_impact	-0,14	0,56	0,8	59,75	10,41	N	0,3	N	0,46	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3661	3661	T	A	MI.11495	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	355	119	S	T	Tca/Aca	-0,01	0,96	0	probably_damaging	1	neutral	0,41	neutral	2,47	neutral	-2,41	deleterious	-2,67	medium_impact	2,87	neutral	0,69	damaging	0,15	deleterious	3,76	23,3	0,27	0,45	neutral	0,31	disease	0,7	disease	0,61	disease	0,64	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,19	medium_impact	1,32	0,74	0,85	59,75	10,41	N	0,39	N	0,68	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3662	3662	C	G	MI.11496	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	356	119	S	W	tCa/tGa	7,34	1	0	probably_damaging	1	neutral	0,17	neutral	2,39	deleterious	-6,83	deleterious	-6,26	high_impact	4,34	neutral	0,75	damaging	0,15	deleterious	4,28	24	0,05	0,35	disease	0,82	disease	0,9	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	-0,11	high_impact	2,6	0,2	0,8	59,75	10,41	P	0,64	P	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3662	3662	C	T	MI.11497	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	356	119	S	L	tCa/tTa	7,34	1	0	probably_damaging	1	neutral	0,81	neutral	2,42	deleterious	-3,59	deleterious	-5,34	medium_impact	2,98	neutral	0,74	damaging	0,11	deleterious	4,55	24,3	0,07	0,35	neutral	0,36	disease	0,88	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,41	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,63	medium_impact	1,41	0,52	0,8	59,75	10,41	N	0,49	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3664	3664	G	T	MI.11498	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	358	120	G	W	Ggg/Tgg	-2,54	0	0	probably_damaging	1	neutral	0,21	neutral	1,07	deleterious	-9,79	deleterious	-7,25	high_impact	4,95	damaging	0,46	damaging	0,04	deleterious	4,39	24,1	0,03	0,35	disease	0,94	disease	0,92	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	-0,05	high_impact	3,13	0,1	0,8	59,43	10,6	P	0,51	P	1	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3664	3664	G	C	MI.11499	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	358	120	G	R	Ggg/Cgg	-2,54	0	0	probably_damaging	1	neutral	0,3	neutral	1,09	deleterious	-7,33	deleterious	-7,22	high_impact	4,95	damaging	0,57	damaging	0,07	deleterious	3,97	23,6	0,02	0,35	disease	0,74	disease	0,89	disease	0,82	disease	0,74	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	0,07	high_impact	3,13	0,48	0,8	59,43	10,6	P	0,62	P	0,99	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8579	8579	C	T	MI.115	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	53	18	P	L	cCc/cTc	1,29	0,83	0	probably_damaging	1	deleterious	0,01	neutral	4,65	neutral	1,06	deleterious	-8,49	medium_impact	2,75	neutral	0,7	neutral	0,47	deleterious	4,08	23,7	0,46	0,65	neutral	0,24	disease	0,89	disease	0,64	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,73	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,26	0,77	0,9	21,24	15,57	N	0,37	N	0,92	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9067	9067	A	G	MI.1150	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	541	181	M	V	Ata/Gta	-11,9	0	0	benign	0,01	deleterious	0	neutral	3,92	neutral	-0,14	neutral	-0,97	low_impact	0,9	neutral	0,88	neutral	0,7	neutral	1	10,64	0,61	0,7	neutral	0,47	neutral	0,46	neutral	0,5	neutral	0,49	0	deleterious	1	deleterious	0,5	neutral	-2	neutral	0,17	medium_impact	1,14	low_impact	-1,4	medium_impact	-0,33	0,65	0,9	45,13	8,06	N	0,4	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3665	3665	G	C	MI.11500	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	359	120	G	A	gGg/gCg	8,95	1	0	probably_damaging	1	neutral	0,47	neutral	1,13	deleterious	-5,7	deleterious	-5,43	high_impact	3,7	damaging	0,31	damaging	0,07	deleterious	3,08	22,5	0,04	0,35	neutral	0,41	disease	0,78	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,25	high_impact	2,04	0,42	0,8	59,43	10,6	P	0,7	P	0,76	polymorphism	0,99	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3665	3665	G	T	MI.11501	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	359	120	G	V	gGg/gTg	8,95	1	0	probably_damaging	1	neutral	0,56	neutral	1,09	deleterious	-7,12	deleterious	-8,16	high_impact	4,95	damaging	0,39	damaging	0,05	deleterious	3,73	23,3	0,02	0,35	disease	0,64	disease	0,89	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,33	high_impact	3,13	0,18	0,8	59,43	10,6	P	0,7	P	1	polymorphism	0,99	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3665	3665	G	A	MI.11502	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	359	120	G	E	gGg/gAg	8,95	1	0	probably_damaging	1	neutral	0,24	neutral	1,1	deleterious	-6,73	deleterious	-7,2	high_impact	4,95	damaging	0,46	damaging	0,04	deleterious	3,9	23,5	0,02	0,35	disease	0,68	disease	0,9	disease	0,81	disease	0,75	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,01	high_impact	3,13	0,21	0,8	59,43	10,6	P	0,72	P	1	polymorphism	0,99	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3667	3667	T	G	MI.11503	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	361	121	W	G	Tga/Gga	-5,98	0	0,01	probably_damaging	1	neutral	0,33	neutral	2,52	deleterious	-4,17	deleterious	-11,75	high_impact	3,94	neutral	0,68	neutral	0,37	deleterious	3,9	23,5	0,05	0,35	disease	0,65	disease	0,88	disease	0,83	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,1	high_impact	2,25	0,06	0,8	59,12	10,6	N	0,48	N	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3667	3667	T	C	MI.11504	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	361	121	W	R	Tga/Cga	-5,98	0	0,01	probably_damaging	1	neutral	0,35	neutral	2,52	deleterious	-4,28	deleterious	-12,68	high_impact	3,94	neutral	0,64	damaging	0,21	deleterious	3,59	23,2	0,03	0,35	disease	0,64	disease	0,92	disease	0,88	disease	0,76	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	0,12	high_impact	2,25	0,06	0,8	59,12	10,6	N	0,46	N	0,98	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3668	3668	G	C	MI.11505	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	362	121	W	S	tGa/tCa	7,34	1	0	probably_damaging	1	neutral	0,41	neutral	2,54	neutral	-2,8	deleterious	-12,67	high_impact	4,57	neutral	0,64	neutral	0,36	deleterious	4,01	23,6	0,05	0,35	disease	0,51	disease	0,93	disease	0,83	disease	0,83	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,19	high_impact	2,8	0,06	0,8	59,12	10,6	P	0,68	P	0,99	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3668	3668	G	T	MI.11506	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	362	121	W	L	tGa/tTa	7,34	1	0	probably_damaging	1	neutral	0,65	neutral	2,63	neutral	-1,08	deleterious	-11,78	high_impact	3,71	neutral	0,65	neutral	0,32	deleterious	4,27	23,9	0,07	0,35	neutral	0,19	disease	0,9	disease	0,83	disease	0,72	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,43	high_impact	2,05	0,06	0,8	59,12	10,6	P	0,61	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3669	3669	A	C	MI.11507	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	363	121	W	C	tgA/tgC	8,95	1	0	probably_damaging	1	neutral	0,18	neutral	2,51	deleterious	-4,71	deleterious	-11,78	high_impact	4,92	neutral	0,64	damaging	0,2	deleterious	3,99	23,6	0,04	0,35	disease	0,7	disease	0,92	disease	0,86	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,09	high_impact	3,11	0,09	0,8	59,12	10,6	P	0,67	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3669	3669	A	T	MI.11508	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	363	121	W	C	tgA/tgT	8,95	1	0	probably_damaging	1	neutral	0,18	neutral	2,51	deleterious	-4,71	deleterious	-11,78	high_impact	4,92	neutral	0,64	damaging	0,2	deleterious	4,1	23,7	0,04	0,35	disease	0,7	disease	0,92	disease	0,86	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,09	high_impact	3,11	0,09	0,8	59,12	10,6	P	0,67	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3670	3670	G	A	MI.11509	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	364	122	A	T	Gca/Aca	0,68	0,99	0	probably_damaging	1	neutral	0,39	neutral	2,5	neutral	-2,79	deleterious	-3,4	medium_impact	3,17	neutral	0,69	damaging	0,07	deleterious	4,15	23,8	0,16	0,45	neutral	0,31	disease	0,83	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,77	low_impact	-3,57	medium_impact	0,17	medium_impact	1,58	0,71	0,85	58,49	10	N	0,44	N	0,7	polymorphism	1	0,15	.	.	.	.	.	pancreatic cancer cell line xenograft / endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	9068	9068	T	C	MI.1151	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	542	181	M	T	aTa/aCa	-0,8	0	0	benign	0,03	deleterious	0	neutral	3,89	neutral	-1,09	deleterious	-2,71	low_impact	1,29	neutral	0,83	neutral	0,73	neutral	1,22	11,85	0,38	0,65	disease	0,67	neutral	0,46	disease	0,51	disease	0,64	3	deleterious	1	deleterious	0,49	neutral	-2	neutral	0,23	medium_impact	0,68	low_impact	-1,4	medium_impact	0,01	0,45	0,9	45,13	8,06	N	0,39	N	0,17	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3670	3670	G	C	MI.11510	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	364	122	A	P	Gca/Cca	0,68	0,99	0	probably_damaging	1	neutral	0,2	neutral	2,44	deleterious	-4,25	deleterious	-4,37	high_impact	4,37	neutral	0,72	damaging	0,06	deleterious	3,81	23,4	0,03	0,35	disease	0,51	disease	0,92	disease	0,63	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	-0,06	high_impact	2,63	0,46	0,8	58,49	10	N	0,53	P	0,96	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3670	3670	G	T	MI.11511	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	364	122	A	S	Gca/Tca	0,68	0,99	0	probably_damaging	1	neutral	0,41	neutral	2,7	neutral	-0,54	neutral	-2,38	low_impact	0,88	neutral	0,82	damaging	0,28	deleterious	3,61	23,2	0,23	0,45	neutral	0,16	neutral	0,34	neutral	0,22	neutral	0,41	2	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,71	low_impact	-3,57	medium_impact	0,19	medium_impact	-0,42	0,34	0,8	58,49	10	N	0,39	N	0,93	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3671	3671	C	T	MI.11512	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	365	122	A	V	gCa/gTa	5,73	1	0	probably_damaging	1	neutral	0,5	neutral	2,53	deleterious	-3,44	deleterious	-3,58	medium_impact	2,83	neutral	0,7	damaging	0,06	deleterious	4,38	24,1	0,1	0,4	neutral	0,34	disease	0,84	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	0,28	medium_impact	1,28	0,72	0,85	58,49	10	N	0,52	P	0,72	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3671	3671	C	A	MI.11513	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	365	122	A	E	gCa/gAa	5,73	1	0	probably_damaging	1	neutral	0,27	neutral	2,46	neutral	-2	deleterious	-4,28	high_impact	4,37	neutral	0,76	damaging	0,08	deleterious	4,55	24,3	0,03	0,35	neutral	0,2	disease	0,91	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,03	high_impact	2,63	0,23	0,8	58,49	10	P	0,65	P	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3671	3671	C	G	MI.11514	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	365	122	A	G	gCa/gGa	5,73	1	0	probably_damaging	1	neutral	0,34	neutral	2,49	neutral	-2,27	deleterious	-3,46	medium_impact	2,44	neutral	0,75	damaging	0,11	deleterious	3,87	23,5	0,21	0,45	neutral	0,26	disease	0,75	neutral	0,48	neutral	0,5	0	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,11	medium_impact	0,94	0,62	0,8	58,49	10	N	0,53	P	0,79	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3673	3673	T	A	MI.11515	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	367	123	S	T	Tca/Aca	-7,13	0	0	probably_damaging	1	neutral	0,39	neutral	2,03	deleterious	-3,79	deleterious	-2,72	medium_impact	3,39	neutral	0,64	neutral	0,37	deleterious	3,79	23,4	0,14	0,4	neutral	0,36	disease	0,72	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,17	medium_impact	1,77	0,51	0,8	59,12	10,43	N	0,42	N	0,68	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3673	3673	T	C	MI.11516	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	367	123	S	P	Tca/Cca	-7,13	0	0	probably_damaging	1	neutral	0,2	neutral	1,98	deleterious	-5,22	deleterious	-4,54	high_impact	4,57	neutral	0,73	neutral	0,49	deleterious	3,97	23,6	0,04	0,35	disease	0,72	disease	0,84	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,06	high_impact	2,8	0,19	0,8	59,12	10,43	N	0,53	P	0,99	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3673	3673	T	G	MI.11517	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	367	123	S	A	Tca/Gca	-7,13	0	0	probably_damaging	1	neutral	0,51	neutral	2,11	neutral	-2,76	deleterious	-2,71	medium_impact	3,18	neutral	0,7	neutral	0,48	deleterious	3,67	23,3	0,15	0,4	neutral	0,34	disease	0,65	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	0,29	medium_impact	1,59	0,4	0,8	59,12	10,43	N	0,38	N	0,46	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3674	3674	C	G	MI.11518	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	368	123	S	W	tCa/tGa	5,5	1	0	probably_damaging	1	neutral	0,19	neutral	1,95	deleterious	-8,14	deleterious	-6,35	high_impact	4,92	neutral	0,72	neutral	0,42	deleterious	4,27	24	0,04	0,35	disease	0,92	disease	0,89	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	-0,08	high_impact	3,11	0,13	0,8	59,12	10,43	P	0,72	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3674	3674	C	T	MI.11519	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	368	123	S	L	tCa/tTa	5,5	1	0	probably_damaging	1	neutral	0,66	neutral	1,99	deleterious	-4,92	deleterious	-5,44	high_impact	4,92	neutral	0,65	neutral	0,42	deleterious	4,56	24,4	0,03	0,35	disease	0,61	disease	0,89	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,44	high_impact	3,11	0,37	0,8	59,12	10,43	P	0,78	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9068	9068	T	A	MI.1152	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	542	181	M	K	aTa/aAa	-0,8	0	0	benign	0,04	deleterious	0	neutral	3,87	neutral	-2,16	deleterious	-3,58	low_impact	1,78	neutral	0,83	neutral	0,49	deleterious	2,33	18,39	0,16	0,65	disease	0,82	disease	0,71	disease	0,74	disease	0,8	6	deleterious	1	deleterious	0,48	neutral	-2	neutral	0,33	medium_impact	0,55	low_impact	-1,4	medium_impact	0,43	0,63	0,9	45,13	8,06	N	0,31	N	0,3	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3676	3676	A	C	MI.11520	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	370	124	N	H	Aac/Cac	-2,08	0	0	probably_damaging	1	neutral	0,54	neutral	2,3	deleterious	-4,38	deleterious	-4,48	high_impact	4,19	damaging	0,58	damaging	0,26	deleterious	3,08	22,5	0,22	0,45	disease	0,64	disease	0,79	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,31	high_impact	2,47	0,13	0,8	59,43	10,55	N	0,41	N	0,97	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3676	3676	A	G	MI.11521	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	370	124	N	D	Aac/Gac	-2,08	0	0	probably_damaging	1	neutral	0,2	neutral	2,37	neutral	-2,63	deleterious	-4,5	high_impact	3,91	neutral	0,75	neutral	0,45	deleterious	3,84	23,4	0,37	0,5	neutral	0,4	disease	0,78	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	-0,06	high_impact	2,23	0,31	0,8	59,43	10,55	N	0,49	N	0,97	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3676	3676	A	T	MI.11522	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	370	124	N	Y	Aac/Tac	-2,08	0	0	probably_damaging	1	neutral	1	neutral	2,29	deleterious	-5,13	deleterious	-7,14	medium_impact	3,44	neutral	0,66	damaging	0,28	deleterious	3,74	23,3	0,07	0,35	disease	0,77	disease	0,88	disease	0,78	disease	0,74	5	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,85	low_impact	-3,57	high_impact	1,96	medium_impact	1,82	0,14	0,8	59,43	10,55	N	0,34	N	1	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3677	3677	A	T	MI.11523	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	371	124	N	I	aAc/aTc	8,49	1	0	probably_damaging	1	neutral	0,41	neutral	2,3	deleterious	-4,72	deleterious	-8,09	high_impact	4,88	neutral	0,77	neutral	0,51	deleterious	3,74	23,3	0,08	0,35	disease	0,72	disease	0,92	disease	0,74	disease	0,75	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,19	high_impact	3,07	0,15	0,8	59,43	10,55	P	0,74	P	1	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3677	3677	A	C	MI.11524	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	371	124	N	T	aAc/aCc	8,49	1	0	probably_damaging	1	neutral	0,39	neutral	2,33	deleterious	-3,46	deleterious	-5,38	high_impact	4,34	neutral	0,61	neutral	0,36	deleterious	3,26	22,8	0,19	0,45	disease	0,5	disease	0,81	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,17	high_impact	2,6	0,32	0,8	59,43	10,55	P	0,66	P	0,96	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3677	3677	A	G	MI.11525	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	371	124	N	S	aAc/aGc	8,49	1	0	probably_damaging	1	neutral	0,47	neutral	2,35	deleterious	-3	deleterious	-4,46	high_impact	3,56	neutral	0,66	neutral	0,64	deleterious	2,94	22	0,3	0,45	neutral	0,43	disease	0,79	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,25	medium_impact	1,92	0,28	0,8	59,43	10,55	P	0,62	P	0,9	polymorphism	0,99	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3678	3678	C	A	MI.11526	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	372	124	N	K	aaC/aaA	8,49	1	0	probably_damaging	1	neutral	0,29	neutral	2,44	neutral	-1,85	deleterious	-5,4	medium_impact	3,5	neutral	0,64	neutral	0,28	deleterious	4,4	24,1	0,24	0,45	neutral	0,32	disease	0,82	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,79	low_impact	-3,57	medium_impact	0,06	medium_impact	1,87	0,28	0,8	59,43	10,55	P	0,66	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3678	3678	C	G	MI.11527	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	372	124	N	K	aaC/aaG	8,49	1	0	probably_damaging	1	neutral	0,29	neutral	2,44	neutral	-1,85	deleterious	-5,4	medium_impact	3,5	neutral	0,64	neutral	0,28	deleterious	4	23,6	0,24	0,45	neutral	0,32	disease	0,82	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,79	low_impact	-3,57	medium_impact	0,06	medium_impact	1,87	0,28	0,8	59,43	10,55	P	0,66	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3679	3679	T	C	MI.11528	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	373	125	S	P	Tca/Cca	-0,93	0,05	0,01	probably_damaging	1	neutral	0,2	neutral	2,33	deleterious	-5,25	deleterious	-4,53	high_impact	4,15	neutral	0,76	damaging	0,12	deleterious	4,04	23,7	0,03	0,35	disease	0,74	disease	0,87	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,06	high_impact	2,44	0,24	0,8	58,49	10,75	N	0,36	N	0,99	polymorphism	1	0,41	.	.	.	.	.	head/neck tumor	.	.	.	.	.	.	.	.	.
chrM	3679	3679	T	A	MI.11529	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	373	125	S	T	Tca/Aca	-0,93	0,05	0,01	probably_damaging	1	neutral	0,38	neutral	2,37	deleterious	-3,87	deleterious	-2,73	high_impact	3,52	neutral	0,77	damaging	0,14	deleterious	3,93	23,5	0,12	0,4	neutral	0,41	disease	0,74	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	0,16	medium_impact	1,89	0,58	0,8	58,49	10,75	N	0,32	N	0,68	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9069	9069	A	T	MI.1153	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	543	181	M	I	atA/atT	5,68	0,9	0	benign	0,01	neutral	0,14	neutral	3,94	neutral	-0,1	neutral	-0,24	neutral_impact	0	neutral	0,83	neutral	0,73	neutral	1,63	14	0,54	0,65	neutral	0,49	neutral	0,5	neutral	0,48	neutral	0,49	0	neutral	0,86	deleterious	0,57	neutral	-6	neutral	0,19	medium_impact	1,14	medium_impact	-0,15	low_impact	-1,1	0,69	0,9	45,13	8,06	N	0,45	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3679	3679	T	G	MI.11530	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	373	125	S	A	Tca/Gca	-0,93	0,05	0,01	probably_damaging	1	neutral	0,56	neutral	2,41	deleterious	-3,53	deleterious	-2,73	high_impact	4,84	neutral	0,71	damaging	0,12	deleterious	3,7	23,3	0,11	0,4	neutral	0,46	disease	0,7	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,33	high_impact	3,04	0,37	0,8	58,49	10,75	P	0,61	P	0,46	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3680	3680	C	G	MI.11531	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	374	125	S	W	tCa/tGa	4,58	1	0	probably_damaging	1	neutral	0,29	neutral	2,3	deleterious	-8,39	deleterious	-6,37	high_impact	4,84	neutral	0,72	damaging	0,09	deleterious	4,34	24	0,04	0,35	disease	0,95	disease	0,91	disease	0,76	disease	0,68	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,06	high_impact	3,04	0,15	0,8	58,49	10,75	P	0,7	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3680	3680	C	T	MI.11532	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	374	125	S	L	tCa/tTa	4,58	1	0	probably_damaging	1	neutral	0,67	neutral	2,34	deleterious	-5,21	deleterious	-5,46	high_impact	4,29	neutral	0,78	damaging	0,09	deleterious	4,63	24,5	0,03	0,35	disease	0,72	disease	0,9	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	0,45	high_impact	2,56	0,36	0,8	58,49	10,75	P	0,55	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3682	3682	A	G	MI.11533	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	376	126	N	D	Aac/Gac	-1,62	0	0	possibly_damaging	0,72	neutral	0,2	neutral	2,74	neutral	-1	neutral	-1,03	medium_impact	2,94	neutral	0,66	damaging	0,25	deleterious	3,84	23,4	0,64	0,7	neutral	0,22	disease	0,61	disease	0,62	disease	0,7	4	neutral	0,85	neutral	0,24	NA	0	deleterious	0,57	low_impact	-1,14	medium_impact	-0,06	medium_impact	1,38	0,29	0,8	22,33	38,03	N	0,42	N	0,68	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3682	3682	A	T	MI.11534	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	376	126	N	Y	Aac/Tac	-1,62	0	0	probably_damaging	0,96	neutral	1	neutral	2,68	deleterious	-3,02	neutral	-1,98	medium_impact	2,04	neutral	0,68	neutral	0,3	deleterious	3,75	23,3	0,08	0,35	neutral	0,44	disease	0,7	disease	0,62	disease	0,7	4	neutral	0,96	deleterious	0,52	deleterious	1	deleterious	0,75	low_impact	-2,05	high_impact	1,96	medium_impact	0,59	0,17	0,8	22,33	38,03	N	0,23	N	0,93	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3682	3682	A	C	MI.11535	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	376	126	N	H	Aac/Cac	-1,62	0	0	probably_damaging	0,95	neutral	0,52	neutral	2,7	neutral	-2,13	neutral	-1,04	medium_impact	2,59	neutral	0,64	neutral	0,28	deleterious	3,08	22,5	0,4	0,5	neutral	0,34	neutral	0,47	disease	0,63	disease	0,53	1	neutral	0,94	neutral	0,29	deleterious	1	deleterious	0,68	low_impact	-1,95	medium_impact	0,29	medium_impact	1,07	0,14	0,8	22,33	38,03	N	0,34	N	0,38	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3683	3683	A	T	MI.11536	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	377	126	N	I	aAc/aTc	8,49	1	0	probably_damaging	0,95	neutral	0,4	neutral	2,69	neutral	-2,63	deleterious	-2,91	low_impact	1,47	neutral	0,67	neutral	0,28	deleterious	3,75	23,3	0,12	0,4	neutral	0,37	disease	0,78	disease	0,58	disease	0,72	4	neutral	0,95	neutral	0,23	neutral	-2	deleterious	0,75	low_impact	-1,95	medium_impact	0,18	medium_impact	0,1	0,14	0,8	22,33	38,03	N	0,5	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3683	3683	A	G	MI.11537	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	377	126	N	S	aAc/aGc	8,49	1	0	possibly_damaging	0,53	neutral	0,64	neutral	2,74	neutral	-0,97	neutral	-0,15	low_impact	1,24	neutral	0,78	neutral	0,28	deleterious	2,94	22	0,55	0,6	neutral	0,14	neutral	0,48	neutral	0,49	neutral	0,43	1	neutral	0,45	deleterious	0,56	neutral	-3	deleterious	0,44	medium_impact	-0,8	medium_impact	0,42	medium_impact	-0,11	0,15	0,8	22,33	38,03	N	0,53	P	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3683	3683	A	C	MI.11538	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	377	126	N	T	aAc/aCc	8,49	1	0	possibly_damaging	0,72	neutral	0,38	neutral	2,72	neutral	-1,35	neutral	-1,05	medium_impact	2,24	neutral	0,63	neutral	0,3	deleterious	3,26	22,8	0,38	0,5	neutral	0,18	neutral	0,49	disease	0,57	disease	0,56	1	neutral	0,74	neutral	0,33	NA	0	deleterious	0,54	low_impact	-1,14	medium_impact	0,16	medium_impact	0,77	0,2	0,8	22,33	38,03	P	0,67	P	0,43	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3684	3684	C	G	MI.11539	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	378	126	N	K	aaC/aaG	6,65	1	0	benign	0,03	neutral	0,37	neutral	3,23	neutral	2,2	neutral	4,14	neutral_impact	-1,8	neutral	0,7	neutral	0,81	neutral	1,27	12,09	0,49	0,55	neutral	0,23	neutral	0,05	neutral	0,26	neutral	0,18	6	neutral	0,61	deleterious	0,67	neutral	-6	neutral	0,12	medium_impact	0,67	medium_impact	0,15	low_impact	-2,76	0,41	0,8	22,33	38,03	P	0,62	P	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9069	9069	A	C	MI.1154	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	543	181	M	I	atA/atC	5,68	0,9	0	benign	0,01	neutral	0,14	neutral	3,94	neutral	-0,1	neutral	-0,24	neutral_impact	0	neutral	0,83	neutral	0,73	neutral	1,55	13,59	0,54	0,65	neutral	0,49	neutral	0,5	neutral	0,48	neutral	0,49	0	neutral	0,86	deleterious	0,57	neutral	-6	neutral	0,19	medium_impact	1,14	medium_impact	-0,15	low_impact	-1,1	0,69	0,9	45,13	8,06	N	0,45	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3684	3684	C	A	MI.11540	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	378	126	N	K	aaC/aaA	6,65	1	0	benign	0,03	neutral	0,37	neutral	3,23	neutral	2,2	neutral	4,14	neutral_impact	-1,8	neutral	0,7	neutral	0,81	neutral	1,69	14,36	0,49	0,55	neutral	0,23	neutral	0,05	neutral	0,26	neutral	0,18	6	neutral	0,61	deleterious	0,67	neutral	-6	neutral	0,12	medium_impact	0,67	medium_impact	0,15	low_impact	-2,76	0,41	0,8	22,33	38,03	P	0,63	P	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3685	3685	T	C	MI.11541	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	379	127	Y	H	Tac/Cac	1,14	1	0	probably_damaging	1	neutral	0,46	neutral	1,59	deleterious	-5,99	deleterious	-4,51	high_impact	4,57	neutral	0,61	damaging	0,03	deleterious	3,66	23,2	0,03	0,35	disease	0,73	disease	0,81	disease	0,82	disease	0,74	5	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,24	high_impact	2,8	0,18	0,8	58,81	10,48	P	0,6	P	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3685	3685	T	A	MI.11542	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	379	127	Y	N	Tac/Aac	1,14	1	0	probably_damaging	1	neutral	0,44	neutral	1,58	deleterious	-7,03	deleterious	-8,11	high_impact	4,92	damaging	0,6	damaging	0,04	deleterious	4,24	23,9	0,02	0,35	disease	0,86	disease	0,88	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,22	high_impact	3,11	0,11	0,8	58,81	10,48	P	0,63	P	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3685	3685	T	G	MI.11543	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	379	127	Y	D	Tac/Gac	1,14	1	0	probably_damaging	1	neutral	0,19	neutral	1,58	deleterious	-8,21	deleterious	-9,01	high_impact	4,92	neutral	0,64	damaging	0,03	deleterious	4	23,6	0,01	0,35	disease	0,93	disease	0,89	disease	0,82	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,08	high_impact	3,11	0,13	0,8	58,81	10,48	P	0,61	P	1	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3686	3686	A	G	MI.11544	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	380	127	Y	C	tAc/tGc	7,34	1	0	probably_damaging	1	neutral	0,17	neutral	1,57	deleterious	-9,12	deleterious	-8,1	high_impact	4,92	damaging	0,59	damaging	0,03	deleterious	3,55	23,1	0,02	0,35	disease	0,94	disease	0,89	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	-0,11	high_impact	3,11	0,13	0,8	58,81	10,48	P	0,62	P	1	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3686	3686	A	C	MI.11545	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	380	127	Y	S	tAc/tCc	7,34	1	0	probably_damaging	1	neutral	1	neutral	1,59	deleterious	-7,63	deleterious	-8,09	high_impact	4,92	damaging	0,54	damaging	0,06	deleterious	3,7	23,3	0,02	0,35	disease	0,85	disease	0,88	disease	0,74	disease	0,73	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,87	low_impact	-3,57	high_impact	1,96	high_impact	3,11	0,12	0,8	58,81	10,48	P	0,64	P	1	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3686	3686	A	T	MI.11546	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	380	127	Y	F	tAc/tTc	7,34	1	0	probably_damaging	1	neutral	0,58	neutral	1,7	neutral	-2,03	deleterious	-3,58	medium_impact	2,94	neutral	0,62	damaging	0,03	deleterious	3,41	23	0,11	0,4	neutral	0,19	disease	0,85	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,77	low_impact	-3,57	medium_impact	0,35	medium_impact	1,38	0,31	0,8	58,81	10,48	N	0,49	N	0,8	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3688	3688	G	C	MI.11547	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	382	128	A	P	Gcc/Ccc	-4,61	0	0	probably_damaging	1	neutral	0,17	neutral	2,5	neutral	-2,14	deleterious	-3,73	medium_impact	2,21	neutral	0,74	neutral	0,54	deleterious	3,77	23,4	0,02	0,35	neutral	0,46	disease	0,86	neutral	0,48	neutral	0,19	6	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,83	low_impact	-3,57	medium_impact	-0,11	medium_impact	0,74	0,47	0,8	14,15	31,17	N	0,39	N	0,99	polymorphism	1	0,13	rs879107244	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3688	3688	G	A	MI.11548	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	382	128	A	T	Gcc/Acc	-4,61	0	0	probably_damaging	1	neutral	0,33	neutral	2,51	neutral	-1,97	deleterious	-3,25	medium_impact	3,4	neutral	0,67	neutral	0,45	deleterious	4,32	24	0,03	0,35	neutral	0,39	disease	0,84	disease	0,59	disease	0,68	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,8	low_impact	-3,57	medium_impact	0,1	medium_impact	1,78	0,68	0,85	14,15	31,17	N	0,43	N	0,55	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	G3688A	Leigh Syndrome	+	-	Reported	2
chrM	3688	3688	G	T	MI.11549	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	382	128	A	S	Gcc/Tcc	-4,61	0	0	probably_damaging	1	neutral	1	neutral	2,74	neutral	-0,29	neutral	-2,3	low_impact	1,65	neutral	0,8	neutral	0,75	deleterious	2,57	19,89	0,12	0,4	neutral	0,23	disease	0,7	neutral	0,22	neutral	0,2	6	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,75	low_impact	-3,57	high_impact	1,96	medium_impact	0,25	0,44	0,8	14,15	31,17	N	0,24	N	0,15	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9070	9070	T	C	MI.1155	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	544	182	S	P	Tca/Cca	-8,43	0	0	possibly_damaging	0,75	neutral	0,15	neutral	4,51	neutral	-2	neutral	-1,35	low_impact	1,45	neutral	0,83	neutral	0,64	deleterious	3,94	23,5	0,21	0,65	neutral	0,35	disease	0,7	disease	0,61	disease	0,56	1	neutral	0,89	neutral	0,2	neutral	-3	deleterious	0,66	low_impact	-1,21	medium_impact	-0,13	medium_impact	0,15	0,62	0,9	23,45	17,69	N	0,33	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3689	3689	C	T	MI.11550	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	383	128	A	V	gCc/gTc	7,11	1	0	probably_damaging	1	neutral	0,41	neutral	2,48	deleterious	-4,28	deleterious	-3,44	high_impact	3,94	neutral	0,68	neutral	0,49	deleterious	4,51	24,3	0,03	0,35	neutral	0,45	disease	0,85	disease	0,58	disease	0,68	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,19	high_impact	2,25	0,64	0,8	14,15	31,17	P	0,66	P	0,75	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3689	3689	C	G	MI.11551	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	383	128	A	G	gCc/gGc	7,11	1	0	probably_damaging	1	neutral	0,45	neutral	2,55	neutral	-1,94	deleterious	-3,36	medium_impact	2,81	neutral	0,75	neutral	0,62	deleterious	4,03	23,6	0,06	0,35	neutral	0,38	disease	0,81	neutral	0,45	disease	0,62	2	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,23	medium_impact	1,27	0,55	0,8	14,15	31,17	P	0,59	P	0,36	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3689	3689	C	A	MI.11552	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	383	128	A	D	gCc/gAc	7,11	1	0	probably_damaging	1	neutral	0,17	neutral	2,47	deleterious	-4,37	deleterious	-4,9	high_impact	4,5	neutral	0,73	neutral	0,38	deleterious	4,53	24,3	0,01	0,35	disease	0,67	disease	0,93	disease	0,72	disease	0,79	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	-0,11	high_impact	2,74	0,39	0,8	14,15	31,17	P	0,72	P	0,96	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3691	3691	C	G	MI.11553	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	385	129	L	V	Ctg/Gtg	-5,98	0	0	probably_damaging	1	neutral	0,48	neutral	2,26	neutral	-2,78	deleterious	-2,66	medium_impact	3,21	neutral	0,66	damaging	0,13	deleterious	3,44	23	0,26	0,45	neutral	0,27	disease	0,66	neutral	0,46	neutral	0,47	1	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	0,26	medium_impact	1,62	0,73	0,85	57,23	9,85	N	0,27	N	0,84	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3691	3691	C	A	MI.11554	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	385	129	L	M	Ctg/Atg	-5,98	0	0	probably_damaging	1	neutral	0,21	neutral	2,27	neutral	-2,63	neutral	-1,66	medium_impact	2,36	neutral	0,8	neutral	0,6	deleterious	3,75	23,3	0,26	0,45	neutral	0,36	disease	0,59	neutral	0,27	neutral	0,21	6	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	-0,05	medium_impact	0,87	0,61	0,8	57,23	9,85	N	0,39	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3692	3692	T	C	MI.11555	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	386	129	L	P	cTg/cCg	-0,93	0	0	probably_damaging	1	neutral	0,19	neutral	2,15	deleterious	-6,14	deleterious	-6,26	high_impact	4,65	neutral	0,74	damaging	0,13	deleterious	3,87	23,5	0,01	0,35	disease	0,66	disease	0,87	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,08	high_impact	2,87	0,28	0,8	57,23	9,85	N	0,45	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3692	3692	T	G	MI.11556	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	386	129	L	R	cTg/cGg	-0,93	0	0	probably_damaging	1	neutral	0,33	neutral	2,16	deleterious	-5,55	deleterious	-5,35	high_impact	4,3	neutral	0,73	damaging	0,12	deleterious	4,18	23,8	0,01	0,35	disease	0,56	disease	0,88	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,1	high_impact	2,57	0,16	0,8	57,23	9,85	N	0,39	N	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3692	3692	T	A	MI.11557	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	386	129	L	Q	cTg/cAg	-0,93	0	0	probably_damaging	1	neutral	0,27	neutral	2,16	deleterious	-5,51	deleterious	-5,32	high_impact	4,65	neutral	0,71	damaging	0,13	deleterious	4,18	23,8	0,02	0,35	disease	0,57	disease	0,85	disease	0,58	disease	0,67	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,03	high_impact	2,87	0,28	0,8	57,23	9,85	N	0,46	N	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3694	3694	A	C	MI.11558	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	388	130	I	L	Atc/Ctc	-0,7	0,02	0	benign	0,26	neutral	0,68	neutral	3,17	neutral	1,25	neutral	-1,13	neutral_impact	0,65	neutral	0,8	damaging	0,19	deleterious	3,74	23,3	0,28	0,45	neutral	0,13	neutral	0,26	neutral	0,16	neutral	0,41	2	neutral	0,22	deleterious	0,71	neutral	-6	neutral	0,21	medium_impact	-0,32	medium_impact	0,46	medium_impact	-0,62	0,52	0,8	22,01	25,8	N	0,31	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3694	3694	A	G	MI.11559	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	388	130	I	V	Atc/Gtc	-0,7	0,02	0	possibly_damaging	0,53	neutral	0,44	neutral	2,69	neutral	-0,66	neutral	-0,69	medium_impact	2,82	neutral	0,8	damaging	0,24	deleterious	2,97	22,1	0,36	0,5	neutral	0,23	neutral	0,36	neutral	0,33	neutral	0,43	1	neutral	0,56	neutral	0,46	NA	0	neutral	0,34	medium_impact	-0,8	medium_impact	0,22	medium_impact	1,27	0,43	0,8	22,01	25,8	N	0,33	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9070	9070	T	A	MI.1156	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	544	182	S	T	Tca/Aca	-8,43	0	0	benign	0,35	neutral	0,39	neutral	4,54	neutral	-1,35	neutral	0,22	neutral_impact	0,46	neutral	0,92	neutral	0,97	deleterious	0,77	9,25	0,41	0,65	neutral	0,48	neutral	0,14	neutral	0,3	neutral	0,29	4	neutral	0,54	deleterious	0,52	neutral	-6	neutral	0,31	medium_impact	-0,5	medium_impact	0,18	medium_impact	-0,7	0,86	0,9	23,45	17,69	N	0,45	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3694	3694	A	T	MI.11560	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	388	130	I	F	Atc/Ttc	-0,7	0,02	0	possibly_damaging	0,89	neutral	0,64	neutral	2,53	neutral	-2,75	neutral	-2,5	medium_impact	2,78	neutral	0,85	neutral	0,82	deleterious	2,64	20,4	0,07	0,35	neutral	0,39	disease	0,8	neutral	0,34	neutral	0,25	5	neutral	0,87	neutral	0,38	NA	0	deleterious	0,71	low_impact	-1,6	medium_impact	0,42	medium_impact	1,24	0,49	0,8	22,01	25,8	N	0,3	N	0,12	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3695	3695	T	C	MI.11561	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	389	130	I	T	aTc/aCc	2,29	0,57	0	possibly_damaging	0,88	neutral	0,34	neutral	2,51	deleterious	-3,26	deleterious	-3,76	high_impact	3,51	neutral	0,7	damaging	0,21	deleterious	3,39	23	0,04	0,35	neutral	0,46	disease	0,71	disease	0,58	disease	0,65	3	neutral	0,89	neutral	0,23	deleterious	1	deleterious	0,67	low_impact	-1,56	medium_impact	0,11	medium_impact	1,88	0,23	0,8	22,01	25,8	N	0,4	N	0,96	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3695	3695	T	G	MI.11562	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	389	130	I	S	aTc/aGc	2,29	0,57	0	probably_damaging	0,91	neutral	0,7	neutral	2,5	deleterious	-3,97	deleterious	-4,45	medium_impact	3,09	neutral	0,74	damaging	0,16	deleterious	4,29	24	0,02	0,35	neutral	0,44	disease	0,85	disease	0,6	disease	0,7	4	neutral	0,89	neutral	0,4	deleterious	1	deleterious	0,75	low_impact	-1,69	medium_impact	0,48	medium_impact	1,51	0,31	0,8	22,01	25,8	N	0,31	N	0,94	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3695	3695	T	A	MI.11563	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	389	130	I	N	aTc/aAc	2,29	0,57	0	probably_damaging	0,97	neutral	0,48	neutral	2,48	deleterious	-4,99	deleterious	-5,37	high_impact	4,06	neutral	0,71	damaging	0,15	deleterious	4,42	24,2	0,04	0,35	disease	0,71	disease	0,87	disease	0,62	disease	0,7	4	neutral	0,97	neutral	0,26	deleterious	2	deleterious	0,81	low_impact	-2,17	medium_impact	0,26	high_impact	2,36	0,36	0,8	22,01	25,8	N	0,4	N	0,99	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3696	3696	C	A	MI.11564	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	390	130	I	M	atC/atA	2,29	0,57	0,01	possibly_damaging	0,52	neutral	0,22	neutral	2,54	neutral	-2,42	neutral	-1,28	low_impact	1,16	neutral	0,83	neutral	0,7	deleterious	2,63	20,4	0,16	0,45	neutral	0,24	neutral	0,39	neutral	0,23	neutral	0,44	1	neutral	0,76	neutral	0,35	neutral	-3	neutral	0,26	medium_impact	-0,78	medium_impact	-0,03	medium_impact	-0,18	0,48	0,8	22,01	25,8	N	0,42	N	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3696	3696	C	G	MI.11565	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	390	130	I	M	atC/atG	2,29	0,57	0,01	possibly_damaging	0,52	neutral	0,22	neutral	2,54	neutral	-2,42	neutral	-1,28	low_impact	1,16	neutral	0,83	neutral	0,7	deleterious	2,13	17,03	0,16	0,45	neutral	0,24	neutral	0,39	neutral	0,23	neutral	0,44	1	neutral	0,76	neutral	0,35	neutral	-3	neutral	0,26	medium_impact	-0,78	medium_impact	-0,03	medium_impact	-0,18	0,48	0,8	22,01	25,8	N	0,43	N	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3697	3697	G	T	MI.11566	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	391	131	G	C	Ggc/Tgc	-8,05	0	0	probably_damaging	1	neutral	0,16	neutral	1,9	deleterious	-8,74	deleterious	-8,18	high_impact	4,94	neutral	0,67	damaging	0,09	deleterious	4,1	23,7	0,01	0,35	disease	0,86	disease	0,92	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	-0,13	high_impact	3,13	0,24	0,8	59,75	10,46	N	0,52	P	0,98	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3697	3697	G	C	MI.11567	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	391	131	G	R	Ggc/Cgc	-8,05	0	0	probably_damaging	1	neutral	0,32	neutral	1,92	deleterious	-8,91	deleterious	-7,26	high_impact	4,94	neutral	0,77	damaging	0,13	deleterious	3,86	23,5	0,02	0,35	disease	0,85	disease	0,9	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	0,09	high_impact	3,13	0,52	0,8	59,75	10,46	P	0,66	P	0,99	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3697	3697	G	A	MI.11568	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	391	131	G	S	Ggc/Agc	-8,05	0	0	probably_damaging	1	neutral	0,59	neutral	1,99	deleterious	-5,32	deleterious	-5,44	medium_impact	3,36	neutral	0,63	damaging	0,14	deleterious	4,16	23,8	0,02	0,35	neutral	0,46	disease	0,89	disease	0,64	disease	0,7	4	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,85	low_impact	-3,57	medium_impact	0,36	medium_impact	1,75	0,56	0,8	59,75	10,46	N	0,36	N	0,99	disease_causing_automatic	0	0,26	rs199476122	Pathogenic|Pathogenic|Pathogenic	Juvenile_myopathy,_encephalopathy,_lactic_acidosis_AND_stroke|Leber_hereditary_optic_neuropathy_with_dystonia|Leber's_optic_atrophy	RCV000010385.4|RCV000010386.2|RCV000056168.1	MedGen:OMIM:Orphanet:SNOMED_CT|MedGen:OMIM|MedGen:OMIM:SNOMED_CT	.	.	.	.	G3697A	MELAS/LS/LDYT	+	+	Cfrm	9
chrM	3698	3698	G	A	MI.11569	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	392	131	G	D	gGc/gAc	7,11	1	0	probably_damaging	1	neutral	0,19	neutral	1,93	deleterious	-8,29	deleterious	-6,36	high_impact	4,94	neutral	0,7	damaging	0,11	deleterious	3,81	23,4	0,02	0,35	disease	0,81	disease	0,92	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	-0,08	high_impact	3,13	0,22	0,8	59,75	10,46	P	0,73	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9070	9070	T	G	MI.1157	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	544	182	S	A	Tca/Gca	-8,43	0	0	benign	0,2	neutral	0,39	neutral	4,6	neutral	-0,5	neutral	-0,12	neutral_impact	0,68	neutral	0,94	neutral	0,93	deleterious	0,83	9,63	0,49	0,65	neutral	0,43	neutral	0,15	neutral	0,4	neutral	0,33	3	neutral	0,53	deleterious	0,6	neutral	-6	neutral	0,21	medium_impact	-0,18	medium_impact	0,18	medium_impact	-0,52	0,75	0,9	23,45	17,69	N	0,42	N	0,17	polymorphism	1	0,01	rs879190502	.	.	.	.	pancreatic cancer cell line	.	.	.	.	.	.	.	.	.
chrM	3698	3698	G	C	MI.11570	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	392	131	G	A	gGc/gCc	7,11	1	0	probably_damaging	1	neutral	0,52	neutral	2,05	deleterious	-5,54	deleterious	-5,44	high_impact	3,7	neutral	0,64	damaging	0,15	deleterious	3,17	22,7	0,02	0,35	neutral	0,43	disease	0,74	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,29	high_impact	2,04	0,36	0,8	59,75	10,46	P	0,56	P	0,76	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3698	3698	G	T	MI.11571	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	392	131	G	V	gGc/gTc	7,11	1	0	probably_damaging	1	neutral	0,46	neutral	1,93	deleterious	-7,88	deleterious	-8,17	high_impact	4,94	damaging	0,54	damaging	0,11	deleterious	3,79	23,4	0,02	0,35	disease	0,77	disease	0,9	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	0,24	high_impact	3,13	0,23	0,8	59,75	10,46	P	0,62	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3700	3700	G	C	MI.11572	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	394	132	A	P	Gca/Cca	-4,15	0	0	probably_damaging	0,97	neutral	0,2	neutral	2,39	deleterious	-3,99	deleterious	-4,45	high_impact	4,47	neutral	0,71	neutral	0,57	deleterious	3,59	23,2	0,02	0,35	disease	0,7	disease	0,93	disease	0,66	disease	0,75	5	deleterious	0,98	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-2,17	medium_impact	-0,06	high_impact	2,72	0,54	0,8	58,18	10,01	N	0,52	P	0,96	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3700	3700	G	T	MI.11573	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	394	132	A	S	Gca/Tca	-4,15	0	0	possibly_damaging	0,78	neutral	0,42	neutral	2,56	neutral	-1,29	deleterious	-2,56	low_impact	1,14	neutral	0,79	neutral	0,6	deleterious	1,9	15,59	0,12	0,4	neutral	0,24	disease	0,77	neutral	0,22	neutral	0,4	2	neutral	0,78	neutral	0,32	neutral	-3	deleterious	0,68	low_impact	-1,27	medium_impact	0,2	medium_impact	-0,19	0,53	0,8	58,18	10,01	N	0,32	N	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3700	3700	G	A	MI.11574	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	394	132	A	T	Gca/Aca	-4,15	0	0	benign	0,15	neutral	0,38	neutral	2,45	neutral	-2,46	deleterious	-3,51	high_impact	3,77	neutral	0,62	neutral	0,49	deleterious	2,27	17,98	0,04	0,35	neutral	0,47	disease	0,86	neutral	0,42	disease	0,69	4	neutral	0,55	deleterious	0,62	neutral	-2	neutral	0,35	medium_impact	-0,04	medium_impact	0,16	high_impact	2,1	0,56	0,8	58,18	10,01	P	0,53	P	0,7	disease_causing_automatic	0	0,18	rs397515508	Pathogenic|Pathogenic|Pathogenic|Pathogenic	Leber's_optic_atrophy|Abnormal_electroretinogram|Optic_neuropathy|Visual_loss	RCV000055708.1|RCV000415448.1|RCV000415448.1|RCV000415448.1	MedGen:OMIM:SNOMED_CT|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen	.	.	CPD	0,15	G3700A	LHON	+	-	Cfrm	2
chrM	3701	3701	C	G	MI.11575	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	395	132	A	G	gCa/gGa	5,73	1	0	possibly_damaging	0,84	neutral	0,33	neutral	2,61	neutral	-0,93	deleterious	-3,53	low_impact	1,9	neutral	0,77	neutral	0,58	deleterious	2,15	17,17	0,08	0,35	neutral	0,23	disease	0,63	neutral	0,23	neutral	0,35	3	neutral	0,86	neutral	0,25	neutral	-3	deleterious	0,66	low_impact	-1,43	medium_impact	0,1	medium_impact	0,47	0,58	0,8	58,18	10,01	P	0,59	P	0,79	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3701	3701	C	A	MI.11576	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	395	132	A	E	gCa/gAa	5,73	1	0	probably_damaging	0,93	neutral	0,27	neutral	2,4	deleterious	-3,5	deleterious	-4,42	high_impact	4,47	neutral	0,72	neutral	0,44	deleterious	2,79	21,3	0,02	0,35	disease	0,6	disease	0,93	disease	0,64	disease	0,72	4	neutral	0,95	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-1,81	medium_impact	0,03	high_impact	2,72	0,37	0,8	58,18	10,01	P	0,72	P	0,96	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3701	3701	C	T	MI.11577	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	395	132	A	V	gCa/gTa	5,73	1	0	possibly_damaging	0,78	neutral	0,49	neutral	2,42	deleterious	-3,08	deleterious	-3,59	high_impact	3,77	neutral	0,77	neutral	0,52	deleterious	2,65	20,5	0,04	0,35	neutral	0,5	disease	0,87	disease	0,53	disease	0,69	4	neutral	0,76	neutral	0,36	deleterious	1	deleterious	0,72	low_impact	-1,27	medium_impact	0,27	high_impact	2,1	0,57	0,8	58,18	10,01	P	0,66	P	0,72	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3703	3703	C	G	MI.11578	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	397	133	L	V	Ctg/Gtg	-3,46	0	0	probably_damaging	1	neutral	0,49	neutral	2,18	neutral	-2,47	deleterious	-2,65	medium_impact	2,42	neutral	0,69	damaging	0,12	deleterious	3,45	23	0,27	0,45	neutral	0,29	disease	0,63	neutral	0,34	neutral	0,4	2	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	0,27	medium_impact	0,93	0,62	0,8	59,43	9,84	N	0,24	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3703	3703	C	A	MI.11579	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	397	133	L	M	Ctg/Atg	-3,46	0	0	probably_damaging	1	neutral	0,22	neutral	2,1	deleterious	-3,33	neutral	-1,76	low_impact	1,86	neutral	0,8	damaging	0,17	deleterious	3,81	23,4	0,27	0,45	neutral	0,32	neutral	0,5	neutral	0,18	neutral	0,22	6	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,72	low_impact	-3,57	medium_impact	-0,03	medium_impact	0,44	0,5	0,8	59,43	9,84	N	0,4	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9071	9071	C	T	MI.1158	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	545	182	S	L	tCa/tTa	-4,96	0	0	benign	0,01	neutral	1	neutral	4,6	neutral	-0,87	neutral	1,6	neutral_impact	-0,55	neutral	0,97	neutral	0,95	deleterious	0,03	2,9	0,36	0,65	neutral	0,39	neutral	0,22	neutral	0,28	neutral	0,38	2	neutral	0,01	deleterious	1	neutral	-6	neutral	0,08	medium_impact	1,14	high_impact	1,98	low_impact	-1,57	0,86	0,9	23,45	17,69	N	0,21	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	3,26	C9071T	Potentially functional variant cosegregating with LHON 3635A	+	-	Reported	1
chrM	3704	3704	T	A	MI.11580	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	398	133	L	Q	cTg/cAg	-0,24	0	0	probably_damaging	1	neutral	0,28	neutral	2,02	deleterious	-6,04	deleterious	-5,42	high_impact	4,21	neutral	0,73	damaging	0,12	deleterious	4,23	23,9	0,02	0,35	disease	0,63	disease	0,83	neutral	0,49	disease	0,65	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,05	high_impact	2,49	0,2	0,8	59,43	9,84	N	0,35	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3704	3704	T	G	MI.11581	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	398	133	L	R	cTg/cGg	-0,24	0	0	probably_damaging	1	neutral	0,35	neutral	2,02	deleterious	-6,08	deleterious	-5,43	high_impact	4,56	neutral	0,76	damaging	0,11	deleterious	4,17	23,8	0,01	0,35	disease	0,62	disease	0,88	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	0,12	high_impact	2,79	0,13	0,8	59,43	9,84	N	0,42	N	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3704	3704	T	C	MI.11582	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	398	133	L	P	cTg/cCg	-0,24	0	0	probably_damaging	1	neutral	0,2	neutral	2,01	deleterious	-6,64	deleterious	-6,33	high_impact	4,56	neutral	0,76	damaging	0,12	deleterious	3,95	23,6	0,01	0,35	disease	0,71	disease	0,86	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	-0,06	high_impact	2,79	0,24	0,8	59,43	9,84	N	0,42	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3706	3706	C	G	MI.11583	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	400	134	R	G	Cga/Gga	-6,67	0	0	probably_damaging	1	neutral	0,36	neutral	1,63	deleterious	-10,68	deleterious	-6,38	high_impact	4,96	damaging	0,43	damaging	0,04	deleterious	4,21	23,9	0,02	0,35	disease	0,88	disease	0,87	disease	0,76	disease	0,68	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,14	high_impact	3,14	0,05	0,8	59,43	10,47	P	0,51	P	1	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3706	3706	C	T	MI.11584	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	400	134	R	W	Cga/Tga	-6,67	0	0	probably_damaging	1	neutral	0,18	neutral	1,6	deleterious	-13,24	deleterious	-7,29	high_impact	4,96	damaging	0,49	damaging	0,02	deleterious	5,13	25,4	0,04	0,35	disease	0,97	disease	0,92	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	-0,09	high_impact	3,14	0,4	0,8	59,43	10,47	P	0,55	P	1	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3707	3707	G	C	MI.11585	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	401	134	R	P	cGa/cCa	5,27	1	0	probably_damaging	1	neutral	0,19	neutral	1,61	deleterious	-11,46	deleterious	-6,38	high_impact	4,96	damaging	0,51	damaging	0,02	deleterious	4,28	24	0,01	0,35	disease	0,92	disease	0,92	disease	0,84	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	-0,08	high_impact	3,14	0,07	0,8	59,43	10,47	P	0,62	P	1	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3707	3707	G	T	MI.11586	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	401	134	R	L	cGa/cTa	5,27	1	0	probably_damaging	1	neutral	0,71	neutral	1,63	deleterious	-11,02	deleterious	-6,38	high_impact	4,96	damaging	0,45	damaging	0,02	deleterious	4,4	24,1	0,02	0,35	disease	0,89	disease	0,95	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,49	high_impact	3,14	0,06	0,8	59,43	10,47	P	0,65	P	1	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3707	3707	G	A	MI.11587	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	401	134	R	Q	cGa/cAa	5,27	1	0	probably_damaging	1	neutral	0,28	neutral	1,65	deleterious	-10,32	deleterious	-3,64	high_impact	4,62	damaging	0,34	damaging	0,02	deleterious	4,48	24,3	0,05	0,35	disease	0,84	disease	0,88	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,05	high_impact	2,85	0,72	0,85	59,43	10,47	P	0,75	P	1	polymorphism	0,96	0,48	.	.	.	.	.	.	COSM1138350	.	.	.	.	.	.	.	.
chrM	3709	3709	G	T	MI.11588	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	403	135	A	S	Gca/Tca	-0,24	0,66	0	probably_damaging	1	neutral	0,42	neutral	2,44	neutral	-1,38	deleterious	-2,69	low_impact	1,86	neutral	0,7	damaging	0,09	deleterious	3,7	23,3	0,27	0,45	neutral	0,17	disease	0,77	neutral	0,2	neutral	0,22	6	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,79	low_impact	-3,57	medium_impact	0,2	medium_impact	0,44	0,33	0,8	59,12	10,41	N	0,29	N	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3709	3709	G	A	MI.11589	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	403	135	A	T	Gca/Aca	-0,24	0,66	0	probably_damaging	1	neutral	0,37	neutral	2,24	deleterious	-3,2	deleterious	-3,61	medium_impact	3,12	neutral	0,65	damaging	0,07	deleterious	4,18	23,8	0,12	0,4	neutral	0,26	disease	0,87	disease	0,52	disease	0,69	4	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,81	low_impact	-3,57	medium_impact	0,15	medium_impact	1,54	0,75	0,85	59,12	10,41	N	0,34	N	0,7	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9071	9071	C	G	MI.1159	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	545	182	S	W	tCa/tGa	-4,96	0	0	probably_damaging	0,91	neutral	0,09	neutral	4,5	deleterious	-3,04	neutral	-1,55	medium_impact	2,25	neutral	0,86	neutral	0,45	deleterious	4,31	24	0,22	0,65	disease	0,82	disease	0,65	neutral	0,48	disease	0,54	1	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,72	low_impact	-1,71	medium_impact	-0,28	medium_impact	0,83	0,61	0,9	23,45	17,69	N	0,33	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3709	3709	G	C	MI.11590	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	403	135	A	P	Gca/Cca	-0,24	0,66	0	probably_damaging	1	neutral	0,19	neutral	2,18	deleterious	-4,68	deleterious	-4,54	high_impact	4,58	neutral	0,73	damaging	0,06	deleterious	3,83	23,4	0,03	0,35	disease	0,54	disease	0,92	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	-0,08	high_impact	2,81	0,5	0,8	59,12	10,41	N	0,47	N	0,96	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3710	3710	C	G	MI.11591	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	404	135	A	G	gCa/gGa	8,95	1	0	probably_damaging	1	neutral	0,42	neutral	2,22	deleterious	-3,53	deleterious	-3,62	medium_impact	2,48	neutral	0,73	damaging	0,11	deleterious	3,91	23,5	0,2	0,45	neutral	0,45	disease	0,83	neutral	0,36	neutral	0,27	5	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,8	low_impact	-3,57	medium_impact	0,2	medium_impact	0,98	0,61	0,8	59,12	10,41	N	0,52	P	0,79	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3710	3710	C	T	MI.11592	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	404	135	A	V	gCa/gTa	8,95	1	0	probably_damaging	1	neutral	0,52	neutral	2,2	deleterious	-3,86	deleterious	-3,64	medium_impact	3,2	neutral	0,66	damaging	0,07	deleterious	4,4	24,1	0,09	0,35	neutral	0,43	disease	0,89	disease	0,55	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,83	low_impact	-3,57	medium_impact	0,29	medium_impact	1,61	0,54	0,8	59,12	10,41	P	0,55	P	0,72	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3710	3710	C	A	MI.11593	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	404	135	A	E	gCa/gAa	8,95	1	0	probably_damaging	1	neutral	0,26	neutral	2,2	deleterious	-4,09	deleterious	-4,52	high_impact	4,24	neutral	0,76	damaging	0,08	deleterious	4,48	24,2	0,05	0,35	neutral	0,18	disease	0,93	disease	0,65	disease	0,72	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,02	high_impact	2,51	0,26	0,8	59,12	10,41	P	0,59	P	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3712	3712	G	A	MI.11594	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	406	136	V	M	Gta/Ata	-2,08	0	0	probably_damaging	1	neutral	0,22	neutral	2,53	neutral	-0,87	deleterious	-2,7	medium_impact	2,98	neutral	0,67	neutral	0,55	deleterious	3,68	23,3	0,21	0,45	neutral	0,29	disease	0,79	disease	0,57	disease	0,56	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	-0,03	medium_impact	1,41	0,98	1	59,12	10,42	N	0,39	N	0,94	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3712	3712	G	C	MI.11595	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	406	136	V	L	Gta/Cta	-2,08	0	0	probably_damaging	1	neutral	0,66	neutral	2,58	neutral	0,22	deleterious	-2,68	medium_impact	2,56	neutral	0,71	neutral	0,5	deleterious	3,54	23,1	0,18	0,45	neutral	0,19	disease	0,82	disease	0,52	disease	0,67	3	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,44	medium_impact	1,05	0,73	0,85	59,12	10,42	N	0,3	N	0,71	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3712	3712	G	T	MI.11596	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	406	136	V	L	Gta/Tta	-2,08	0	0	probably_damaging	1	neutral	0,66	neutral	2,58	neutral	0,22	deleterious	-2,68	medium_impact	2,56	neutral	0,71	neutral	0,5	deleterious	3,64	23,2	0,18	0,45	neutral	0,19	disease	0,82	disease	0,52	disease	0,67	3	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,44	medium_impact	1,05	0,73	0,85	59,12	10,42	N	0,3	N	0,71	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3713	3713	T	C	MI.11597	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	407	136	V	A	gTa/gCa	7,11	1	0	probably_damaging	1	neutral	0,52	neutral	2,81	neutral	0,61	deleterious	-3,64	medium_impact	2,12	neutral	0,73	neutral	0,6	deleterious	3,57	23,1	0,12	0,4	neutral	0,15	disease	0,53	neutral	0,35	neutral	0,21	6	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,29	medium_impact	0,66	0,28	0,8	59,12	10,42	P	0,57	P	0,64	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	T3713C	LHON (putative)	+	-	Reported	1
chrM	3713	3713	T	G	MI.11598	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	407	136	V	G	gTa/gGa	7,11	1	0	probably_damaging	1	neutral	0,34	neutral	2,55	neutral	-2,46	deleterious	-6,37	high_impact	3,65	neutral	0,71	neutral	0,55	deleterious	3,81	23,4	0,03	0,35	neutral	0,46	disease	0,88	disease	0,61	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,11	medium_impact	2	0,21	0,8	59,12	10,42	P	0,65	P	0,95	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3713	3713	T	A	MI.11599	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	407	136	V	E	gTa/gAa	7,11	1	0	probably_damaging	1	neutral	0,27	neutral	2,54	neutral	-2,98	deleterious	-5,47	high_impact	4,21	neutral	0,72	neutral	0,46	deleterious	4,89	24,9	0,02	0,35	disease	0,55	disease	0,91	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,03	high_impact	2,49	0,17	0,8	59,12	10,42	P	0,7	P	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8579	8579	C	A	MI.116	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	53	18	P	H	cCc/cAc	1,29	0,83	0	probably_damaging	1	deleterious	0,03	neutral	4,57	neutral	-0,99	deleterious	-7,7	medium_impact	3,1	neutral	0,74	neutral	0,43	deleterious	3,84	23,4	0,3	0,65	disease	0,8	disease	0,86	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,82	low_impact	-3,6	medium_impact	-0,56	medium_impact	1,56	0,65	0,9	21,24	15,57	N	0,33	N	0,91	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9073	9073	A	G	MI.1160	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	547	183	T	A	Acc/Gcc	-1,95	0	0	benign	0,02	neutral	0,51	neutral	4,69	neutral	0,54	neutral	-0,86	neutral_impact	0,26	neutral	0,97	neutral	0,86	deleterious	2,59	20,2	0,67	0,75	neutral	0,26	neutral	0,29	neutral	0,42	neutral	0,43	1	neutral	0,47	deleterious	0,75	neutral	-6	neutral	0,14	medium_impact	0,85	medium_impact	0,3	medium_impact	-0,88	0,48	0,9	15,04	22,29	N	0,28	N	0,03	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3715	3715	G	T	MI.11600	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	409	137	A	S	Gcc/Tcc	-8,05	0	0	probably_damaging	1	neutral	0,41	neutral	2,18	neutral	-2,45	deleterious	-2,73	medium_impact	2,79	damaging	0,58	damaging	0,05	deleterious	3,68	23,3	0,18	0,45	neutral	0,32	disease	0,87	neutral	0,48	disease	0,57	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,82	low_impact	-3,57	medium_impact	0,19	medium_impact	1,25	0,55	0,8	59,12	10,53	N	0,27	N	0,93	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3715	3715	G	A	MI.11601	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	409	137	A	T	Gcc/Acc	-8,05	0	0	probably_damaging	1	neutral	0,3	neutral	2,07	deleterious	-3,62	deleterious	-3,63	high_impact	4,32	damaging	0,58	damaging	0,03	deleterious	4,22	23,9	0,08	0,35	neutral	0,3	disease	0,85	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,07	high_impact	2,58	0,71	0,85	59,12	10,53	N	0,35	N	0,7	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3715	3715	G	C	MI.11602	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	409	137	A	P	Gcc/Ccc	-8,05	0	0	probably_damaging	1	neutral	0,14	neutral	2,02	deleterious	-5,1	deleterious	-4,55	high_impact	3,98	neutral	0,6	damaging	0,03	deleterious	3,76	23,3	0,02	0,35	disease	0,66	disease	0,91	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	-0,17	high_impact	2,29	0,55	0,8	59,12	10,53	N	0,35	N	0,96	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3716	3716	C	G	MI.11603	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	410	137	A	G	gCc/gGc	5,73	1	0	probably_damaging	1	neutral	0,54	neutral	2,06	deleterious	-3,94	deleterious	-3,65	high_impact	3,98	neutral	0,64	damaging	0,05	deleterious	3,95	23,6	0,1	0,4	disease	0,52	disease	0,86	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,31	high_impact	2,29	0,62	0,8	59,12	10,53	P	0,58	P	0,79	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3716	3716	C	T	MI.11604	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	410	137	A	V	gCc/gTc	5,73	1	0	probably_damaging	1	neutral	0,43	neutral	2,04	deleterious	-4,23	deleterious	-3,62	high_impact	3,83	neutral	0,7	damaging	0,07	deleterious	4,41	24,2	0,06	0,35	neutral	0,32	disease	0,89	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,21	high_impact	2,16	0,63	0,8	59,12	10,53	P	0,59	P	0,72	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3716	3716	C	A	MI.11605	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	410	137	A	D	gCc/gAc	5,73	1	0	probably_damaging	1	neutral	0,15	neutral	2,02	deleterious	-4,92	deleterious	-5,46	high_impact	4,87	neutral	0,65	damaging	0,02	deleterious	4,6	24,4	0,02	0,35	disease	0,63	disease	0,94	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	-0,15	high_impact	3,06	0,31	0,8	59,12	10,53	P	0,74	P	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3718	3718	C	G	MI.11606	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	412	138	Q	E	Caa/Gaa	-5,07	0	0	probably_damaging	1	neutral	0,21	neutral	2,34	neutral	-2,89	deleterious	-2,73	high_impact	4,93	neutral	0,69	neutral	0,3	deleterious	3,03	22,3	0,16	0,45	neutral	0,42	disease	0,84	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,05	high_impact	3,12	0,28	0,8	60,06	10,45	P	0,73	P	0,93	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3718	3718	C	A	MI.11607	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	412	138	Q	K	Caa/Aaa	-5,07	0	0	probably_damaging	1	neutral	0,22	neutral	2,37	neutral	-2,4	deleterious	-3,64	high_impact	4,58	neutral	0,67	damaging	0,26	deleterious	3,89	23,5	0,09	0,35	neutral	0,39	disease	0,9	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,03	high_impact	2,81	0,18	0,8	60,06	10,45	N	0,55	P	0,98	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3719	3719	A	T	MI.11608	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	413	138	Q	L	cAa/cTa	7,11	1	0	probably_damaging	1	neutral	0,83	neutral	2,34	neutral	-2,79	deleterious	-6,37	high_impact	3,96	neutral	0,67	neutral	0,32	deleterious	3,78	23,4	0,04	0,35	neutral	0,18	disease	0,92	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,66	high_impact	2,27	0,12	0,8	60,06	10,45	P	0,54	P	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3719	3719	A	G	MI.11609	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	413	138	Q	R	cAa/cGa	7,11	1	0	probably_damaging	1	neutral	0,49	neutral	2,34	neutral	-2,84	deleterious	-3,64	high_impact	4,04	neutral	0,68	damaging	0,26	deleterious	3,41	23	0,09	0,35	neutral	0,41	disease	0,9	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,27	high_impact	2,34	0,17	0,8	60,06	10,45	P	0,67	P	0,95	polymorphism	0,98	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9073	9073	A	T	MI.1161	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	547	183	T	S	Acc/Tcc	-1,95	0	0	benign	0,28	neutral	0,55	neutral	4,67	neutral	0,03	neutral	0,53	neutral_impact	-1,31	neutral	0,91	neutral	0,96	neutral	1,2	11,73	0,51	0,65	neutral	0,31	neutral	0,17	neutral	0,23	neutral	0,25	5	neutral	0,35	deleterious	0,64	neutral	-6	neutral	0,35	medium_impact	-0,37	medium_impact	0,34	low_impact	-2,22	0,56	0,9	15,04	22,29	N	0,32	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3719	3719	A	C	MI.11610	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	413	138	Q	P	cAa/cCa	7,11	1	0	probably_damaging	1	neutral	0,15	neutral	2,27	deleterious	-4,81	deleterious	-5,44	high_impact	4,58	neutral	0,69	neutral	0,32	deleterious	3,21	22,7	0,03	0,35	disease	0,66	disease	0,91	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	-0,15	high_impact	2,81	0,13	0,8	60,06	10,45	P	0,7	P	0,98	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3720	3720	A	C	MI.11611	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	414	138	Q	H	caA/caC	6,42	1	0,02	probably_damaging	1	neutral	0,41	neutral	2,28	deleterious	-4,49	deleterious	-4,55	high_impact	4,93	damaging	0,59	damaging	0,21	deleterious	3,29	22,8	0,09	0,35	disease	0,63	disease	0,85	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,19	high_impact	3,12	0,39	0,8	60,06	10,45	P	0,82	P	0,98	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3720	3720	A	T	MI.11612	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	414	138	Q	H	caA/caT	6,42	1	0,02	probably_damaging	1	neutral	0,41	neutral	2,28	deleterious	-4,49	deleterious	-4,55	high_impact	4,93	damaging	0,59	damaging	0,21	deleterious	3,51	23,1	0,09	0,35	disease	0,63	disease	0,85	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,19	high_impact	3,12	0,39	0,8	60,06	10,45	P	0,83	P	0,98	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3721	3721	A	T	MI.11613	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	415	139	T	S	Aca/Tca	2,06	1	0	possibly_damaging	0,85	neutral	0,6	neutral	2,78	neutral	-0,11	deleterious	-3,62	medium_impact	2,21	neutral	0,7	neutral	0,49	deleterious	3,15	22,6	0,37	0,5	neutral	0,18	disease	0,83	neutral	0,49	disease	0,66	3	neutral	0,83	neutral	0,38	NA	0	deleterious	0,7	low_impact	-1,46	medium_impact	0,37	medium_impact	0,74	0,6	0,8	56,29	9,53	N	0,46	N	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3721	3721	A	C	MI.11614	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	415	139	T	P	Aca/Cca	2,06	1	0	probably_damaging	0,98	neutral	0,15	neutral	2,59	neutral	-2,61	deleterious	-5,39	high_impact	4,49	neutral	0,76	neutral	0,43	deleterious	3,41	23	0,03	0,35	disease	0,52	disease	0,91	disease	0,75	disease	0,75	5	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-2,34	medium_impact	-0,15	high_impact	2,73	0,29	0,8	56,29	9,53	P	0,64	P	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3721	3721	A	G	MI.11615	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	415	139	T	A	Aca/Gca	2,06	1	0	possibly_damaging	0,74	neutral	1	neutral	2,68	neutral	0,06	deleterious	-4,52	medium_impact	3,1	neutral	0,68	neutral	0,53	deleterious	3,34	22,9	0,25	0,45	neutral	0,2	disease	0,72	disease	0,52	neutral	0,44	1	neutral	0,74	deleterious	0,63	NA	0	deleterious	0,62	low_impact	-1,18	high_impact	1,96	medium_impact	1,52	0,3	0,8	56,29	9,53	N	0,44	N	0,65	polymorphism	1	0,11	rs878927280	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3722	3722	C	A	MI.11616	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	416	139	T	K	aCa/aAa	8,49	1	0	probably_damaging	0,94	neutral	0,32	neutral	2,64	neutral	-1,77	deleterious	-5,43	high_impact	4,14	neutral	0,7	neutral	0,33	deleterious	4,48	24,2	0,05	0,35	neutral	0,34	disease	0,92	disease	0,7	disease	0,75	5	neutral	0,95	neutral	0,19	deleterious	2	deleterious	0,8	low_impact	-1,87	medium_impact	0,09	high_impact	2,43	0,31	0,8	56,29	9,53	P	0,66	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3722	3722	C	T	MI.11617	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	416	139	T	M	aCa/aTa	8,49	1	0	possibly_damaging	0,52	neutral	0,18	neutral	2,68	neutral	1,89	deleterious	-5,42	low_impact	1,9	neutral	0,71	neutral	0,55	deleterious	3,92	23,5	0,12	0,4	neutral	0,14	disease	0,75	neutral	0,32	neutral	0,22	6	neutral	0,8	neutral	0,33	neutral	-3	deleterious	0,47	medium_impact	-0,78	medium_impact	-0,09	medium_impact	0,47	0,52	0,8	56,29	9,53	P	0,59	P	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3724	3724	A	T	MI.11618	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	418	140	I	F	Atc/Ttc	-8,28	0	0	probably_damaging	1	neutral	0,7	neutral	2,18	deleterious	-4,44	deleterious	-3,64	high_impact	4,48	neutral	0,68	damaging	0,09	deleterious	3,87	23,5	0,04	0,35	disease	0,72	disease	0,9	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,48	high_impact	2,72	0,63	0,8	59,12	10,2	N	0,39	N	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3724	3724	A	G	MI.11619	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	418	140	I	V	Atc/Gtc	-8,28	0	0	probably_damaging	1	neutral	0,67	neutral	2,54	neutral	-0,89	neutral	-0,89	medium_impact	2,46	neutral	0,75	damaging	0,16	deleterious	2,94	22	0,59	0,65	neutral	0,17	disease	0,53	neutral	0,4	neutral	0,34	3	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,69	low_impact	-3,57	medium_impact	0,45	medium_impact	0,96	0,63	0,8	59,12	10,2	N	0,25	N	0,73	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9073	9073	A	C	MI.1162	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	547	183	T	P	Acc/Ccc	-1,95	0	0	possibly_damaging	0,68	neutral	0,32	neutral	4,61	neutral	-0,9	neutral	-0,88	neutral_impact	-1,08	neutral	0,76	neutral	0,81	neutral	1,72	14,51	0,23	0,65	neutral	0,25	neutral	0,29	neutral	0,37	neutral	0,42	2	neutral	0,75	neutral	0,32	neutral	-3	deleterious	0,61	low_impact	-1,07	medium_impact	0,11	low_impact	-2,02	0,71	0,9	15,04	22,29	N	0,34	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3724	3724	A	C	MI.11620	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	418	140	I	L	Atc/Ctc	-8,28	0	0	probably_damaging	1	neutral	0,84	neutral	2,36	neutral	-1,82	neutral	-1,82	medium_impact	2,68	neutral	0,73	damaging	0,08	deleterious	3,72	23,3	0,25	0,45	neutral	0,29	disease	0,79	disease	0,53	disease	0,65	3	deleterious	1	neutral	0,42	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,68	medium_impact	1,15	0,56	0,8	59,12	10,2	N	0,24	N	0,82	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3725	3725	T	G	MI.11621	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	419	140	I	S	aTc/aGc	8,49	1	0	probably_damaging	1	neutral	0,5	neutral	2,16	deleterious	-5,14	deleterious	-5,44	high_impact	4,83	neutral	0,72	damaging	0,12	deleterious	4,21	23,9	0,01	0,35	disease	0,79	disease	0,92	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,28	high_impact	3,03	0,33	0,8	59,12	10,2	P	0,75	P	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3725	3725	T	A	MI.11622	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	419	140	I	N	aTc/aAc	8,49	1	0	probably_damaging	1	neutral	0,32	neutral	2,15	deleterious	-6,16	deleterious	-6,36	high_impact	4,48	neutral	0,78	damaging	0,12	deleterious	4,59	24,4	0,03	0,35	disease	0,88	disease	0,91	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	0,09	high_impact	2,72	0,48	0,8	59,12	10,2	P	0,6	P	1	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3725	3725	T	C	MI.11623	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	419	140	I	T	aTc/aCc	8,49	1	0	probably_damaging	1	neutral	0,42	neutral	2,18	deleterious	-4,28	deleterious	-4,52	high_impact	4,83	neutral	0,67	damaging	0,09	deleterious	3,41	23	0,02	0,35	disease	0,67	disease	0,82	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,2	high_impact	3,03	0,28	0,8	59,12	10,2	P	0,76	P	0,96	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3726	3726	C	G	MI.11624	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	420	140	I	M	atC/atG	5,5	1	0	probably_damaging	1	neutral	0,23	neutral	2,19	deleterious	-4,11	deleterious	-2,72	high_impact	4,48	neutral	0,81	damaging	0,14	deleterious	3,37	22,9	0,12	0,4	disease	0,68	disease	0,79	disease	0,68	disease	0,67	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	-0,02	high_impact	2,72	0,65	0,8	59,12	10,2	P	0,64	P	0,74	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3726	3726	C	A	MI.11625	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	420	140	I	M	atC/atA	5,5	1	0	probably_damaging	1	neutral	0,23	neutral	2,19	deleterious	-4,11	deleterious	-2,72	high_impact	4,48	neutral	0,81	damaging	0,14	deleterious	3,78	23,4	0,12	0,4	disease	0,68	disease	0,79	disease	0,68	disease	0,67	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	-0,02	high_impact	2,72	0,65	0,8	59,12	10,2	P	0,65	P	0,74	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3727	3727	T	C	MI.11626	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	421	141	S	P	Tca/Cca	-2,31	0	0	probably_damaging	1	neutral	0,14	neutral	2,03	deleterious	-4,27	deleterious	-4,57	high_impact	4,94	neutral	0,73	damaging	0,04	deleterious	3,94	23,5	0,03	0,35	disease	0,63	disease	0,87	disease	0,82	disease	0,73	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,17	high_impact	3,13	0,31	0,8	58,18	10,4	P	0,73	P	0,99	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3727	3727	T	A	MI.11627	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	421	141	S	T	Tca/Aca	-2,31	0	0	probably_damaging	1	neutral	0,43	neutral	2,06	deleterious	-3,77	deleterious	-2,73	high_impact	4,25	neutral	0,62	damaging	0,05	deleterious	3,68	23,3	0,19	0,45	neutral	0,38	disease	0,71	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,21	high_impact	2,52	0,71	0,85	58,18	10,4	N	0,4	N	0,68	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3727	3727	T	G	MI.11628	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	421	141	S	A	Tca/Gca	-2,31	0	0	probably_damaging	1	neutral	1	neutral	2,11	deleterious	-3,01	deleterious	-2,74	medium_impact	3,46	neutral	0,63	damaging	0,11	deleterious	3,62	23,2	0,2	0,45	neutral	0,28	disease	0,63	disease	0,7	disease	0,68	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,75	low_impact	-3,57	high_impact	1,96	medium_impact	1,83	0,49	0,8	58,18	10,4	N	0,26	N	0,46	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3728	3728	C	G	MI.11629	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	422	141	S	W	tCa/tGa	7,34	1	0	probably_damaging	1	neutral	0,13	neutral	1,98	deleterious	-8,02	deleterious	-6,39	high_impact	4,94	neutral	0,7	damaging	0,04	deleterious	4,33	24	0,04	0,35	disease	0,79	disease	0,92	disease	0,76	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,19	high_impact	3,13	0,11	0,8	58,18	10,4	P	0,69	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9074	9074	C	T	MI.1163	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	548	183	T	I	aCc/aTc	-0,8	0	0	possibly_damaging	0,61	neutral	0,41	neutral	4,64	neutral	-0,87	neutral	-2,48	neutral_impact	0,34	neutral	0,92	neutral	0,67	deleterious	2,68	20,7	0,43	0,65	disease	0,51	disease	0,6	neutral	0,45	neutral	0,48	0	neutral	0,64	neutral	0,4	neutral	-3	deleterious	0,58	medium_impact	-0,94	medium_impact	0,2	medium_impact	-0,81	0,73	0,9	15,04	22,29	N	0,31	N	0,64	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3728	3728	C	T	MI.11630	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	422	141	S	L	tCa/tTa	7,34	1	0	probably_damaging	1	neutral	0,62	neutral	2,01	deleterious	-4,87	deleterious	-5,48	high_impact	4,13	neutral	0,64	damaging	0,02	deleterious	4,64	24,5	0,03	0,35	neutral	0,24	disease	0,9	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,39	high_impact	2,42	0,44	0,8	58,18	10,4	P	0,54	P	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3730	3730	T	G	MI.11631	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	424	142	Y	D	Tat/Gat	-3,46	0	0	probably_damaging	1	neutral	0,18	neutral	1,58	deleterious	-6,73	deleterious	-9,13	high_impact	4,93	neutral	0,74	damaging	0,13	deleterious	3,97	23,6	0,02	0,35	disease	0,74	disease	0,93	disease	0,78	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	-0,09	high_impact	3,12	0,06	0,8	58,81	10,47	P	0,63	P	1	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3730	3730	T	A	MI.11632	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	424	142	Y	N	Tat/Aat	-3,46	0	0	probably_damaging	1	neutral	0,26	neutral	1,58	deleterious	-6,45	deleterious	-8,21	high_impact	4,93	neutral	0,7	damaging	0,14	deleterious	4,03	23,6	0,05	0,35	disease	0,65	disease	0,9	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,02	high_impact	3,12	0,04	0,8	58,81	10,47	P	0,58	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3730	3730	T	C	MI.11633	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	424	142	Y	H	Tat/Cat	-3,46	0	0	probably_damaging	1	neutral	0,45	neutral	1,59	deleterious	-5,96	deleterious	-4,57	high_impact	4,93	neutral	0,66	damaging	0,12	deleterious	3,57	23,2	0,1	0,4	disease	0,69	disease	0,88	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,23	high_impact	3,12	0,11	0,8	58,81	10,47	P	0,73	P	1	polymorphism	1	0,48	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	3731	3731	A	C	MI.11634	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	425	142	Y	S	tAt/tCt	7,34	1	0	probably_damaging	1	neutral	0,54	neutral	1,59	deleterious	-6,02	deleterious	-8,21	high_impact	4,39	neutral	0,67	damaging	0,16	deleterious	3,64	23,2	0,05	0,35	neutral	0,4	disease	0,91	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,31	high_impact	2,65	0,11	0,8	58,81	10,47	P	0,53	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3731	3731	A	T	MI.11635	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	425	142	Y	F	tAt/tTt	7,34	1	0	probably_damaging	1	neutral	0,6	neutral	1,7	deleterious	-3,78	deleterious	-3,65	medium_impact	3,12	neutral	0,68	damaging	0,17	deleterious	3,26	22,8	0,15	0,4	neutral	0,48	disease	0,89	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,85	low_impact	-3,57	medium_impact	0,37	medium_impact	1,54	0,28	0,8	58,81	10,47	P	0,55	P	0,8	polymorphism	0,99	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3731	3731	A	G	MI.11636	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	425	142	Y	C	tAt/tGt	7,34	1	0	probably_damaging	1	neutral	0,15	neutral	1,57	deleterious	-7,85	deleterious	-8,22	high_impact	4,93	neutral	0,74	damaging	0,12	deleterious	3,35	22,9	0,05	0,35	neutral	0,47	disease	0,9	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	-0,15	high_impact	3,12	0,06	0,8	58,81	10,47	P	0,65	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3733	3733	G	C	MI.11637	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	427	143	E	Q	Gaa/Caa	-6,9	0	0	probably_damaging	0,95	neutral	0,6	neutral	1,75	deleterious	-6,3	deleterious	-2,73	high_impact	4,96	neutral	0,67	neutral	0,58	deleterious	3,35	22,9	0,06	0,35	disease	0,84	disease	0,79	disease	0,74	disease	0,7	4	neutral	0,95	neutral	0,33	deleterious	2	deleterious	0,87	low_impact	-1,95	medium_impact	0,37	high_impact	3,14	0,49	0,8	59,43	10,32	P	0,74	P	0,91	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	G3733C	LHON	-	+	Reported	1
chrM	3733	3733	G	A	MI.11638	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	427	143	E	K	Gaa/Aaa	-6,9	0	0	possibly_damaging	0,85	neutral	0,23	neutral	1,77	deleterious	-6,28	deleterious	-3,64	high_impact	4,96	neutral	0,63	neutral	0,4	deleterious	4,47	24,2	0,03	0,35	disease	0,82	disease	0,9	disease	0,78	disease	0,71	4	neutral	0,9	neutral	0,19	deleterious	1	deleterious	0,84	low_impact	-1,46	medium_impact	-0,02	high_impact	3,14	0,7	0,85	59,43	10,32	P	0,79	P	0,99	disease_causing_automatic	0	0,48	rs199476125	Pathogenic	Leber's_optic_atrophy	RCV000010389.2	MedGen:OMIM:SNOMED_CT	.	.	.	.	G3733A	LHON	+	+	Cfrm	6
chrM	3734	3734	A	C	MI.11639	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	428	143	E	A	gAa/gCa	5,73	1	0	possibly_damaging	0,74	neutral	1	neutral	1,75	deleterious	-6,5	deleterious	-5,46	high_impact	4,96	neutral	0,68	neutral	0,59	deleterious	3,71	23,3	0,03	0,35	disease	0,84	disease	0,76	disease	0,73	disease	0,7	4	neutral	0,74	deleterious	0,63	deleterious	1	deleterious	0,73	low_impact	-1,18	high_impact	1,96	high_impact	3,14	0,34	0,8	59,43	10,32	P	0,7	P	0,74	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9074	9074	C	A	MI.1164	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	548	183	T	N	aCc/aAc	-0,8	0	0	possibly_damaging	0,75	neutral	0,38	neutral	4,61	neutral	-0,96	neutral	-0,95	neutral_impact	-0,06	neutral	0,92	neutral	0,96	deleterious	2,39	18,73	0,56	0,65	neutral	0,33	neutral	0,48	neutral	0,28	neutral	0,45	1	neutral	0,76	neutral	0,32	neutral	-3	deleterious	0,58	low_impact	-1,21	medium_impact	0,17	low_impact	-1,15	0,73	0,9	15,04	22,29	N	0,38	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3734	3734	A	G	MI.11640	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	428	143	E	G	gAa/gGa	5,73	1	0	benign	0,08	neutral	0,25	neutral	1,74	deleterious	-6,79	deleterious	-6,37	high_impact	4,62	neutral	0,7	neutral	0,65	deleterious	4,28	24	0,02	0,35	disease	0,83	disease	0,85	disease	0,75	disease	0,7	4	neutral	0,72	deleterious	0,59	neutral	-2	neutral	0,37	medium_impact	0,25	medium_impact	0,01	high_impact	2,85	0,15	0,8	59,43	10,32	P	0,63	P	0,61	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3734	3734	A	T	MI.11641	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	428	143	E	V	gAa/gTa	5,73	1	0	probably_damaging	0,96	neutral	0,78	neutral	1,73	deleterious	-7,75	deleterious	-6,38	high_impact	4,96	neutral	0,63	neutral	0,53	deleterious	4,19	23,8	0,02	0,35	disease	0,92	disease	0,91	disease	0,75	disease	0,66	3	neutral	0,95	neutral	0,41	deleterious	2	deleterious	0,89	low_impact	-2,05	medium_impact	0,58	high_impact	3,14	0,23	0,8	59,43	10,32	P	0,73	P	0,83	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3735	3735	A	T	MI.11642	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	429	143	E	D	gaA/gaT	8,49	1	0	possibly_damaging	0,85	neutral	0,16	neutral	1,8	deleterious	-5,09	deleterious	-2,73	high_impact	4,62	neutral	0,71	neutral	0,55	deleterious	3,87	23,5	0,09	0,35	disease	0,7	disease	0,81	disease	0,75	disease	0,72	4	neutral	0,92	neutral	0,16	deleterious	1	deleterious	0,77	low_impact	-1,46	medium_impact	-0,13	high_impact	2,85	0,53	0,8	59,43	10,32	P	0,73	P	0,9	polymorphism	0,98	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3735	3735	A	C	MI.11643	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	429	143	E	D	gaA/gaC	8,49	1	0	possibly_damaging	0,85	neutral	0,16	neutral	1,8	deleterious	-5,09	deleterious	-2,73	high_impact	4,62	neutral	0,71	neutral	0,55	deleterious	3,7	23,3	0,09	0,35	disease	0,7	disease	0,81	disease	0,75	disease	0,72	4	neutral	0,92	neutral	0,16	deleterious	1	deleterious	0,77	low_impact	-1,46	medium_impact	-0,13	high_impact	2,85	0,53	0,8	59,43	10,32	P	0,73	P	0,9	polymorphism	0,98	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3736	3736	G	C	MI.11644	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	430	144	V	L	Gtc/Ctc	4,58	1	0,01	benign	0,39	neutral	0,61	neutral	2,45	neutral	-1,51	deleterious	-2,71	medium_impact	2,62	neutral	0,72	neutral	0,49	neutral	1,62	13,94	0,26	0,45	neutral	0,18	disease	0,82	disease	0,57	disease	0,66	3	neutral	0,35	deleterious	0,61	neutral	-3	neutral	0,34	medium_impact	-0,57	medium_impact	0,38	medium_impact	1,1	0,32	0,8	57,55	10,07	N	0,52	P	0,69	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3736	3736	G	A	MI.11645	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	430	144	V	I	Gtc/Atc	4,58	1	0,01	benign	0,05	neutral	0,47	neutral	2,66	neutral	-0,5	neutral	-0,89	low_impact	1,92	neutral	0,68	neutral	0,6	neutral	1,68	14,29	0,41	0,5	neutral	0,18	disease	0,58	neutral	0,31	neutral	0,2	6	neutral	0,48	deleterious	0,71	neutral	-6	neutral	0,19	medium_impact	0,45	medium_impact	0,25	medium_impact	0,49	0,72	0,85	57,55	10,07	P	0,7	P	0,08	polymorphism	1	0,03	rs201513497	.	.	.	.	.	.	CPD	0,89	G3736A	LHON	.	.	Reported	1
chrM	3736	3736	G	T	MI.11646	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	430	144	V	F	Gtc/Ttc	4,58	1	0,01	benign	0,11	neutral	0,54	neutral	2,25	deleterious	-4,24	deleterious	-4,54	high_impact	4,74	neutral	0,71	neutral	0,5	deleterious	1,99	16,13	0,03	0,35	neutral	0,48	disease	0,93	disease	0,65	disease	0,75	5	neutral	0,37	deleterious	0,72	neutral	-2	neutral	0,33	medium_impact	0,1	medium_impact	0,31	high_impact	2,95	0,28	0,8	57,55	10,07	P	0,66	P	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3737	3737	T	C	MI.11647	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	431	144	V	A	gTc/gCc	7,11	1	0	possibly_damaging	0,64	neutral	0,65	neutral	2,27	deleterious	-3,66	deleterious	-3,63	medium_impact	3,1	neutral	0,7	neutral	0,57	neutral	1,73	14,6	0,08	0,35	neutral	0,37	disease	0,65	disease	0,61	disease	0,65	3	neutral	0,57	deleterious	0,51	NA	0	deleterious	0,54	medium_impact	-0,99	medium_impact	0,43	medium_impact	1,52	0,11	0,8	57,55	10,07	P	0,59	P	0,87	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3737	3737	T	G	MI.11648	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	431	144	V	G	gTc/gGc	7,11	1	0	probably_damaging	0,93	neutral	0,28	neutral	2,23	deleterious	-5,79	deleterious	-6,36	high_impact	4,18	neutral	0,79	neutral	0,57	deleterious	2,22	17,61	0,01	0,35	disease	0,62	disease	0,87	disease	0,65	disease	0,71	4	neutral	0,94	neutral	0,18	deleterious	2	deleterious	0,76	low_impact	-1,81	medium_impact	0,05	high_impact	2,46	0,31	0,8	57,55	10,07	P	0,63	P	0,96	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3737	3737	T	A	MI.11649	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	431	144	V	D	gTc/gAc	7,11	1	0	probably_damaging	0,95	neutral	0,16	neutral	2,22	deleterious	-6,38	deleterious	-6,36	high_impact	4,74	neutral	0,73	neutral	0,49	deleterious	4,21	23,9	0,01	0,35	disease	0,73	disease	0,92	disease	0,74	disease	0,73	5	neutral	0,97	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-1,95	medium_impact	-0,13	high_impact	2,95	0,14	0,8	57,55	10,07	P	0,71	P	0,99	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9074	9074	C	G	MI.1165	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	548	183	T	S	aCc/aGc	-0,8	0	0	benign	0,28	neutral	0,55	neutral	4,67	neutral	0,03	neutral	0,53	neutral_impact	-1,31	neutral	0,91	neutral	0,96	deleterious	0,85	9,77	0,51	0,65	neutral	0,31	neutral	0,17	neutral	0,23	neutral	0,25	5	neutral	0,35	deleterious	0,64	neutral	-6	neutral	0,35	medium_impact	-0,37	medium_impact	0,34	low_impact	-2,22	0,56	0,9	15,04	22,29	N	0,3	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3739	3739	A	C	MI.11650	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	433	145	T	P	Acc/Ccc	-9,43	0	0	probably_damaging	0,96	neutral	0,17	neutral	2,77	neutral	1,5	deleterious	-4,08	low_impact	1,89	neutral	0,64	damaging	0,19	deleterious	3,43	23	0,08	0,35	neutral	0,18	disease	0,93	disease	0,66	disease	0,77	5	neutral	0,97	neutral	0,11	neutral	-2	deleterious	0,76	low_impact	-2,05	medium_impact	-0,11	medium_impact	0,46	0,42	0,8	53,14	8,83	N	0,3	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3739	3739	A	T	MI.11651	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	433	145	T	S	Acc/Tcc	-9,43	0	0	benign	0,2	neutral	0,66	neutral	2,94	neutral	0,49	neutral	-1,4	low_impact	1,14	neutral	0,85	neutral	0,84	neutral	1,09	11,16	0,38	0,5	neutral	0,15	neutral	0,13	neutral	0,15	neutral	0,26	5	neutral	0,22	deleterious	0,73	neutral	-6	neutral	0,19	medium_impact	-0,19	medium_impact	0,44	medium_impact	-0,19	0,65	0,8	53,14	8,83	N	0,38	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3739	3739	A	G	MI.11652	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	433	145	T	A	Acc/Gcc	-9,43	0	0	benign	0,08	neutral	0,52	neutral	2,83	neutral	1,7	deleterious	-2,8	medium_impact	1,97	neutral	0,86	neutral	0,39	deleterious	3,45	23	0,24	0,45	neutral	0,17	disease	0,63	neutral	0,38	neutral	0,36	3	neutral	0,41	deleterious	0,72	neutral	-3	neutral	0,19	medium_impact	0,25	medium_impact	0,29	medium_impact	0,53	0,36	0,8	53,14	8,83	N	0,31	N	0,65	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3740	3740	C	G	MI.11653	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	434	145	T	S	aCc/aGc	3,67	0,99	0	benign	0,2	neutral	0,66	neutral	2,94	neutral	0,49	neutral	-1,4	low_impact	1,14	neutral	0,85	neutral	0,84	neutral	1,33	12,43	0,38	0,5	neutral	0,15	neutral	0,13	neutral	0,15	neutral	0,26	5	neutral	0,22	deleterious	0,73	neutral	-6	neutral	0,19	medium_impact	-0,19	medium_impact	0,44	medium_impact	-0,19	0,65	0,8	53,14	8,83	N	0,45	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3740	3740	C	T	MI.11654	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	434	145	T	I	aCc/aTc	3,67	0,99	0	probably_damaging	0,92	neutral	0,59	neutral	2,72	neutral	0,51	deleterious	-4,39	medium_impact	2,38	neutral	0,69	damaging	0,12	deleterious	3,96	23,6	0,14	0,4	neutral	0,19	disease	0,86	neutral	0,5	disease	0,7	4	neutral	0,91	neutral	0,34	deleterious	1	deleterious	0,7	low_impact	-1,75	medium_impact	0,36	medium_impact	0,89	0,74	0,85	53,14	8,83	N	0,36	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3740	3740	C	A	MI.11655	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	434	145	T	N	aCc/aAc	3,67	0,99	0	possibly_damaging	0,83	neutral	0,26	neutral	2,73	neutral	-1,79	deleterious	-2,93	medium_impact	2,67	neutral	0,64	damaging	0,14	deleterious	3,59	23,2	0,31	0,45	neutral	0,38	disease	0,86	neutral	0,39	disease	0,71	4	neutral	0,88	neutral	0,22	NA	0	deleterious	0,73	low_impact	-1,4	medium_impact	0,02	medium_impact	1,14	0,62	0,8	53,14	8,83	P	0,5	N	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3742	3742	C	A	MI.11656	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	436	146	L	M	Cta/Ata	-5,75	0	0	benign	0,39	neutral	0,24	neutral	2,03	deleterious	-3,5	neutral	-1,63	low_impact	1,62	neutral	0,82	neutral	0,81	deleterious	2,48	19,33	0,31	0,45	neutral	0,29	neutral	0,37	neutral	0,34	neutral	0,41	2	neutral	0,72	neutral	0,43	neutral	-6	neutral	0,3	medium_impact	-0,57	medium_impact	-0,01	medium_impact	0,23	0,58	0,8	16,98	26,75	N	0,42	N	0,11	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3742	3742	C	G	MI.11657	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	436	146	L	V	Cta/Gta	-5,75	0	0	possibly_damaging	0,64	neutral	0,56	neutral	2,06	deleterious	-3,16	deleterious	-2,66	high_impact	3,56	neutral	0,63	neutral	0,54	neutral	1,6	13,86	0,26	0,45	neutral	0,47	disease	0,57	disease	0,52	disease	0,54	1	neutral	0,59	neutral	0,46	deleterious	1	deleterious	0,53	medium_impact	-0,99	medium_impact	0,33	medium_impact	1,92	0,49	0,8	16,98	26,75	N	0,35	N	0,41	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3743	3743	T	C	MI.11658	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	437	146	L	P	cTa/cCa	-0,47	0	0	probably_damaging	0,93	neutral	0,17	neutral	1,94	deleterious	-6,77	deleterious	-6,27	high_impact	4,53	neutral	0,67	neutral	0,48	deleterious	3,49	23,1	0,03	0,35	disease	0,91	disease	0,83	disease	0,71	disease	0,68	4	neutral	0,96	neutral	0,12	deleterious	2	deleterious	0,86	low_impact	-1,81	medium_impact	-0,11	high_impact	2,77	0,28	0,8	16,98	26,75	N	0,46	N	0,87	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3743	3743	T	G	MI.11659	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	437	146	L	R	cTa/cGa	-0,47	0	0	probably_damaging	0,9	neutral	0,29	neutral	1,95	deleterious	-6,22	deleterious	-5,37	high_impact	4,53	neutral	0,68	neutral	0,44	deleterious	2,55	19,79	0,03	0,35	disease	0,89	disease	0,86	disease	0,71	disease	0,68	4	neutral	0,92	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-1,65	medium_impact	0,06	high_impact	2,77	0,14	0,8	16,98	26,75	N	0,48	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9076	9076	A	T	MI.1166	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	550	184	I	F	Att/Ttt	-16,07	0	0	benign	0,35	neutral	0,67	neutral	4,57	neutral	-1,52	deleterious	-2,5	low_impact	1,44	neutral	0,88	neutral	0,39	deleterious	2,4	18,83	0,55	0,65	disease	0,67	disease	0,59	disease	0,53	disease	0,53	1	neutral	0,28	deleterious	0,66	neutral	-6	neutral	0,36	medium_impact	-0,5	medium_impact	0,47	medium_impact	0,14	0,58	0,9	13,72	9,63	N	0,23	N	0,9	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3743	3743	T	A	MI.11660	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	437	146	L	Q	cTa/cAa	-0,47	0	0	probably_damaging	0,93	neutral	0,33	neutral	1,95	deleterious	-6,15	deleterious	-5,33	high_impact	4,53	neutral	0,67	neutral	0,48	deleterious	3,73	23,3	0,05	0,35	disease	0,88	disease	0,78	disease	0,59	disease	0,69	4	neutral	0,94	neutral	0,2	deleterious	2	deleterious	0,8	low_impact	-1,81	medium_impact	0,1	high_impact	2,77	0,29	0,8	16,98	26,75	N	0,47	N	0,86	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3745	3745	G	C	MI.11661	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	439	147	A	P	Gcc/Ccc	-0,24	0,57	0	probably_damaging	0,93	neutral	0,21	neutral	2,46	deleterious	-3,69	deleterious	-2,77	medium_impact	3,38	neutral	0,67	neutral	0,31	deleterious	3,78	23,4	0,05	0,35	disease	0,52	disease	0,92	disease	0,69	disease	0,76	5	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,82	low_impact	-1,81	medium_impact	-0,05	medium_impact	1,76	0,59	0,8	39,94	9,35	N	0,34	N	0,94	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3745	3745	G	A	MI.11662	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	439	147	A	T	Gcc/Acc	-0,24	0,57	0	benign	0,05	neutral	0,4	neutral	2,55	neutral	-1,79	neutral	-2,42	low_impact	1,7	neutral	0,77	neutral	0,68	deleterious	4,14	23,8	0,21	0,45	neutral	0,21	disease	0,65	neutral	0,49	neutral	0,44	1	neutral	0,56	deleterious	0,68	neutral	-6	neutral	0,19	medium_impact	0,45	medium_impact	0,18	medium_impact	0,3	0,78	0,85	39,94	9,35	N	0,28	N	0,51	polymorphism	1	0,11	.	.	.	.	.	.	.	.	2,37	G3745A	Possible adaptive high altitude variant	.	.	Reported	1
chrM	3745	3745	G	T	MI.11663	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	439	147	A	S	Gcc/Tcc	-0,24	0,57	0	benign	0,13	neutral	0,43	neutral	2,65	neutral	-0,88	neutral	-0,93	low_impact	1,55	neutral	0,73	neutral	0,56	deleterious	3,65	23,2	0,31	0,45	neutral	0,23	disease	0,69	neutral	0,34	neutral	0,23	6	neutral	0,5	deleterious	0,65	neutral	-6	neutral	0,24	medium_impact	0,02	medium_impact	0,21	medium_impact	0,17	0,53	0,8	39,94	9,35	N	0,34	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3746	3746	C	G	MI.11664	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	440	147	A	G	gCc/gGc	5,04	1	0	possibly_damaging	0,64	neutral	0,33	neutral	2,73	neutral	-0,36	neutral	2,32	neutral_impact	0,12	neutral	0,73	neutral	0,59	neutral	1,2	11,75	0,3	0,45	neutral	0,14	neutral	0,14	neutral	0,26	neutral	0,22	6	neutral	0,72	neutral	0,35	neutral	-3	deleterious	0,44	medium_impact	-0,99	medium_impact	0,1	low_impact	-1,08	0,68	0,85	39,94	9,35	P	0,65	P	0,69	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3746	3746	C	T	MI.11665	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	440	147	A	V	gCc/gTc	5,04	1	0	benign	0,08	neutral	0,51	neutral	2,49	neutral	-2,96	deleterious	-3,05	medium_impact	2,12	neutral	0,76	neutral	0,57	deleterious	4,38	24,1	0,21	0,45	neutral	0,17	disease	0,77	neutral	0,48	neutral	0,29	4	neutral	0,42	deleterious	0,72	neutral	-3	neutral	0,22	medium_impact	0,25	medium_impact	0,29	medium_impact	0,66	0,69	0,85	39,94	9,35	P	0,55	P	0,6	polymorphism	1	0,11	rs199684756	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3746	3746	C	A	MI.11666	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	440	147	A	D	gCc/gAc	5,04	1	0	possibly_damaging	0,83	neutral	0,21	neutral	2,47	deleterious	-3,42	neutral	-2,48	high_impact	3,92	neutral	0,73	neutral	0,38	deleterious	4,59	24,4	0,04	0,35	neutral	0,49	disease	0,92	disease	0,68	disease	0,75	5	neutral	0,9	neutral	0,19	deleterious	1	deleterious	0,75	low_impact	-1,4	medium_impact	-0,05	high_impact	2,24	0,41	0,8	39,94	9,35	P	0,68	P	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3748	3748	A	T	MI.11667	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	442	148	I	F	Atc/Ttc	-13,57	0	0	possibly_damaging	0,83	neutral	0,65	neutral	2,67	neutral	-1,49	deleterious	-2,7	low_impact	1,47	neutral	0,85	damaging	0,14	deleterious	2	16,22	0,17	0,45	neutral	0,27	disease	0,73	neutral	0,48	neutral	0,3	4	neutral	0,8	neutral	0,41	neutral	-3	deleterious	0,64	low_impact	-1,4	medium_impact	0,43	medium_impact	0,1	0,46	0,8	59,43	8,86	N	0,22	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3748	3748	A	C	MI.11668	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	442	148	I	L	Atc/Ctc	-13,57	0	0	benign	0,05	neutral	0,65	neutral	3,31	neutral	1,98	neutral	0	neutral_impact	-0,66	neutral	0,87	neutral	0,75	neutral	-0,85	0,03	0,19	0,45	neutral	0,15	neutral	0,18	neutral	0,23	neutral	0,32	4	neutral	0,28	deleterious	0,8	neutral	-6	neutral	0,1	medium_impact	0,45	medium_impact	0,43	low_impact	-1,76	0,39	0,8	59,43	8,86	N	0,37	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3748	3748	A	G	MI.11669	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	442	148	I	V	Atc/Gtc	-13,57	0	0	possibly_damaging	0,52	neutral	0,55	neutral	2,75	neutral	-0,47	neutral	-0,87	medium_impact	2,43	neutral	0,76	damaging	0,15	neutral	1,06	10,99	0,31	0,5	neutral	0,17	neutral	0,38	disease	0,53	neutral	0,45	1	neutral	0,49	deleterious	0,52	NA	0	neutral	0,3	medium_impact	-0,78	medium_impact	0,32	medium_impact	0,93	0,33	0,8	59,43	8,86	N	0,28	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9076	9076	A	C	MI.1167	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	550	184	I	L	Att/Ctt	-16,07	0	0	benign	0,03	neutral	1	neutral	4,73	neutral	0,24	neutral	-0,78	neutral_impact	0,09	neutral	0,76	neutral	0,67	deleterious	0,33	5,98	0,45	0,65	neutral	0,25	neutral	0,22	neutral	0,27	neutral	0,36	3	neutral	0,03	deleterious	0,99	neutral	-6	neutral	0,12	medium_impact	0,68	high_impact	1,98	low_impact	-1,02	0,56	0,9	13,72	9,63	N	0,32	N	0,72	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3749	3749	T	C	MI.11670	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	443	148	I	T	aTc/aCc	1,37	0,71	0	possibly_damaging	0,86	neutral	0,37	neutral	2,63	neutral	-2,31	deleterious	-3,55	medium_impact	2,25	neutral	0,87	neutral	0,53	neutral	1,54	13,53	0,12	0,4	neutral	0,36	disease	0,51	neutral	0,49	neutral	0,49	0	neutral	0,86	neutral	0,26	NA	0	deleterious	0,65	low_impact	-1,49	medium_impact	0,15	medium_impact	0,78	0,33	0,8	59,43	8,86	N	0,38	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3749	3749	T	G	MI.11671	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	443	148	I	S	aTc/aGc	1,37	0,71	0	probably_damaging	0,93	neutral	0,56	neutral	2,62	neutral	-2,79	deleterious	-4,48	medium_impact	2,43	neutral	0,72	damaging	0,12	deleterious	2,51	19,55	0,06	0,35	neutral	0,36	disease	0,78	disease	0,56	disease	0,7	4	neutral	0,92	neutral	0,32	deleterious	1	deleterious	0,71	low_impact	-1,81	medium_impact	0,33	medium_impact	0,93	0,24	0,8	59,43	8,86	N	0,23	N	0,94	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3749	3749	T	A	MI.11672	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	443	148	I	N	aTc/aAc	1,37	0,71	0	probably_damaging	0,96	neutral	0,24	neutral	2,6	deleterious	-3,79	deleterious	-5,4	high_impact	3,63	neutral	0,69	damaging	0,13	deleterious	4,01	23,6	0,13	0,4	disease	0,6	disease	0,8	disease	0,58	disease	0,71	4	neutral	0,97	neutral	0,14	deleterious	2	deleterious	0,77	low_impact	-2,05	medium_impact	-0,01	medium_impact	1,98	0,27	0,8	59,43	8,86	N	0,36	N	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3750	3750	C	G	MI.11673	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	444	148	I	M	atC/atG	5,5	0,95	0	possibly_damaging	0,87	neutral	0,27	neutral	2,66	neutral	-1,7	neutral	-1,34	low_impact	1,4	neutral	0,89	damaging	0,21	neutral	1,45	13,03	0,28	0,45	neutral	0,28	disease	0,53	neutral	0,46	neutral	0,36	3	neutral	0,9	neutral	0,2	neutral	-3	deleterious	0,62	low_impact	-1,53	medium_impact	0,03	medium_impact	0,03	0,51	0,8	59,43	8,86	P	0,55	P	0,78	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3750	3750	C	A	MI.11674	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	444	148	I	M	atC/atA	5,5	0,95	0	possibly_damaging	0,87	neutral	0,27	neutral	2,66	neutral	-1,7	neutral	-1,34	low_impact	1,4	neutral	0,89	damaging	0,21	deleterious	1,97	16,03	0,28	0,45	neutral	0,28	disease	0,53	neutral	0,46	neutral	0,36	3	neutral	0,9	neutral	0,2	neutral	-3	deleterious	0,62	low_impact	-1,53	medium_impact	0,03	medium_impact	0,03	0,51	0,8	59,43	8,86	P	0,55	P	0,78	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3751	3751	A	T	MI.11675	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	445	149	I	F	Att/Ttt	-5,98	0	0	probably_damaging	1	neutral	0,7	neutral	2,59	neutral	-1,59	deleterious	-3,65	medium_impact	3,29	neutral	0,68	damaging	0,14	deleterious	3,71	23,3	0,15	0,4	neutral	0,37	disease	0,83	disease	0,58	disease	0,66	3	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,77	low_impact	-3,57	medium_impact	0,48	medium_impact	1,69	0,4	0,8	59,12	10,46	N	0,28	N	0,95	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3751	3751	A	G	MI.11676	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	445	149	I	V	Att/Gtt	-5,98	0	0	probably_damaging	1	neutral	0,5	neutral	2,68	neutral	0,79	neutral	-0,91	medium_impact	2,67	neutral	0,66	damaging	0,16	deleterious	3	22,2	0,39	0,5	neutral	0,18	neutral	0,47	disease	0,53	neutral	0,35	3	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,67	low_impact	-3,57	medium_impact	0,28	medium_impact	1,14	0,48	0,8	59,12	10,46	N	0,33	N	0,73	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3751	3751	A	C	MI.11677	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	445	149	I	L	Att/Ctt	-5,98	0	0	probably_damaging	1	neutral	0,65	neutral	2,69	neutral	0	neutral	-1,82	medium_impact	2,72	neutral	0,69	damaging	0,12	deleterious	3,72	23,3	0,19	0,45	neutral	0,15	disease	0,72	neutral	0,5	neutral	0,22	6	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,43	medium_impact	1,19	0,38	0,8	59,12	10,46	N	0,24	N	0,82	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3752	3752	T	C	MI.11678	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	446	149	I	T	aTt/aCt	6,65	1	0	probably_damaging	1	neutral	0,39	neutral	2,62	neutral	-0,51	deleterious	-4,55	medium_impact	3,15	neutral	0,66	damaging	0,13	deleterious	3,31	22,9	0,11	0,4	neutral	0,24	disease	0,72	disease	0,56	disease	0,51	0	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,17	medium_impact	1,56	0,37	0,8	59,12	10,46	P	0,55	P	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3752	3752	T	A	MI.11679	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	446	149	I	N	aTt/aAt	6,65	1	0	probably_damaging	1	neutral	0,31	neutral	2,57	neutral	-2,48	deleterious	-6,37	high_impact	4,64	neutral	0,73	damaging	0,15	deleterious	4,4	24,1	0,15	0,4	disease	0,52	disease	0,84	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,08	high_impact	2,86	0,22	0,8	59,12	10,46	P	0,68	P	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9076	9076	A	G	MI.1168	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	550	184	I	V	Att/Gtt	-16,07	0	0	benign	0,03	neutral	0,51	neutral	4,67	neutral	-0,08	neutral	-0,59	low_impact	1,38	neutral	0,9	neutral	0,63	deleterious	0,17	4,33	0,7	0,75	neutral	0,49	neutral	0,2	neutral	0,37	neutral	0,33	3	neutral	0,46	deleterious	0,74	neutral	-6	neutral	0,15	medium_impact	0,68	medium_impact	0,3	medium_impact	0,09	0,51	0,9	13,72	9,63	N	0,37	N	0,58	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3752	3752	T	G	MI.11680	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	446	149	I	S	aTt/aGt	6,65	1	0	probably_damaging	1	neutral	0,41	neutral	2,66	neutral	1,12	deleterious	-5,45	medium_impact	2,37	neutral	0,73	damaging	0,18	deleterious	4,25	23,9	0,07	0,35	neutral	0,17	disease	0,87	disease	0,6	disease	0,68	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	0,19	medium_impact	0,88	0,25	0,8	59,12	10,46	N	0,49	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3753	3753	T	G	MI.11681	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	447	149	I	M	atT/atG	7,34	1	0,01	probably_damaging	1	neutral	0,22	neutral	2,59	neutral	-1,53	deleterious	-2,73	medium_impact	2,85	neutral	0,73	damaging	0,15	deleterious	3,37	22,9	0,34	0,5	neutral	0,37	disease	0,73	disease	0,54	disease	0,62	2	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	-0,03	medium_impact	1,3	0,56	0,8	59,12	10,46	P	0,6	P	0,74	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3753	3753	T	A	MI.11682	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	447	149	I	M	atT/atA	7,34	1	0,01	probably_damaging	1	neutral	0,22	neutral	2,59	neutral	-1,53	deleterious	-2,73	medium_impact	2,85	neutral	0,73	damaging	0,15	deleterious	3,72	23,3	0,34	0,5	neutral	0,37	disease	0,73	disease	0,54	disease	0,62	2	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	-0,03	medium_impact	1,3	0,56	0,8	59,12	10,46	P	0,6	P	0,74	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3754	3754	C	A	MI.11683	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	448	150	L	M	Cta/Ata	-4,84	0	0	possibly_damaging	0,52	neutral	0,31	neutral	2,25	deleterious	-3,57	neutral	-1,57	medium_impact	2,2	neutral	0,71	neutral	0,68	deleterious	3,67	23,3	0,24	0,45	neutral	0,37	neutral	0,38	neutral	0,36	neutral	0,44	1	neutral	0,67	neutral	0,4	NA	0	neutral	0,35	medium_impact	-0,78	medium_impact	0,08	medium_impact	0,73	0,45	0,8	17,92	14,15	N	0,42	N	0,63	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3754	3754	C	G	MI.11684	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	448	150	L	V	Cta/Gta	-4,84	0	0	benign	0,12	neutral	0,66	neutral	2,53	neutral	-0,99	neutral	-1,98	low_impact	1,72	neutral	0,84	neutral	0,75	deleterious	3,32	22,9	0,22	0,45	neutral	0,15	neutral	0,47	neutral	0,36	neutral	0,38	2	neutral	0,23	deleterious	0,77	neutral	-6	neutral	0,17	medium_impact	0,06	medium_impact	0,44	medium_impact	0,31	0,42	0,8	17,92	14,15	N	0,27	N	0,59	polymorphism	1	0,04	rs28615151	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3755	3755	T	C	MI.11685	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	449	150	L	P	cTa/cCa	-0,47	0	0	probably_damaging	0,98	neutral	0,1	neutral	2,2	deleterious	-6,11	deleterious	-5,75	high_impact	3,92	neutral	0,7	neutral	0,46	deleterious	3,79	23,4	0,03	0,35	disease	0,72	disease	0,82	disease	0,71	disease	0,72	4	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,85	low_impact	-2,34	medium_impact	-0,26	high_impact	2,24	0,34	0,8	17,92	14,15	N	0,39	N	0,93	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3755	3755	T	A	MI.11686	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	449	150	L	Q	cTa/cAa	-0,47	0	0	probably_damaging	0,96	neutral	0,14	neutral	2,2	deleterious	-5,59	deleterious	-5,11	high_impact	4,28	neutral	0,72	neutral	0,5	deleterious	3,96	23,6	0,04	0,35	disease	0,66	disease	0,73	disease	0,59	disease	0,65	3	neutral	0,98	neutral	0,09	deleterious	2	deleterious	0,77	low_impact	-2,05	medium_impact	-0,17	high_impact	2,55	0,31	0,8	17,92	14,15	N	0,46	N	0,93	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3755	3755	T	G	MI.11687	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	449	150	L	R	cTa/cGa	-0,47	0	0	probably_damaging	0,96	neutral	0,17	neutral	2,2	deleterious	-5,57	deleterious	-5,17	high_impact	4,28	neutral	0,69	neutral	0,45	deleterious	4,04	23,7	0,03	0,35	disease	0,64	disease	0,84	disease	0,7	disease	0,73	5	neutral	0,97	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-2,05	medium_impact	-0,11	high_impact	2,55	0,15	0,8	17,92	14,15	N	0,44	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3757	3757	C	A	MI.11688	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	451	151	L	M	Cta/Ata	-20	0	0	probably_damaging	0,98	neutral	0,2	neutral	2,24	deleterious	-3,08	neutral	-1,75	low_impact	1,65	neutral	0,81	damaging	0,18	deleterious	3,72	23,3	0,25	0,45	neutral	0,41	neutral	0,4	neutral	0,34	neutral	0,44	1	deleterious	0,99	neutral	0,11	neutral	-2	deleterious	0,69	low_impact	-2,34	medium_impact	-0,06	medium_impact	0,25	0,49	0,8	60,06	10,09	N	0,33	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3757	3757	C	G	MI.11689	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	451	151	L	V	Cta/Gta	-20	0	0	benign	0,3	neutral	0,56	neutral	2,32	neutral	-2,21	deleterious	-2,57	medium_impact	2,58	neutral	0,8	damaging	0,2	deleterious	3,39	23	0,21	0,45	neutral	0,28	disease	0,56	neutral	0,49	neutral	0,21	6	neutral	0,34	deleterious	0,63	neutral	-3	neutral	0,27	medium_impact	-0,41	medium_impact	0,33	medium_impact	1,07	0,42	0,8	60,06	10,09	N	0,22	N	0,84	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9077	9077	T	C	MI.1169	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	551	184	I	T	aTt/aCt	2,21	0,55	0	benign	0	neutral	0,59	neutral	4,55	neutral	-1,74	deleterious	-2,65	neutral_impact	0,2	neutral	0,96	neutral	0,85	deleterious	0,2	4,65	0,48	0,65	disease	0,62	neutral	0,29	neutral	0,33	disease	0,58	1	neutral	0,4	deleterious	0,8	neutral	-6	neutral	0,18	high_impact	2,09	medium_impact	0,38	medium_impact	-0,93	0,49	0,9	13,72	9,63	N	0,26	N	0,7	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3758	3758	T	C	MI.11690	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	452	151	L	P	cTa/cCa	-0,7	0	0	probably_damaging	1	neutral	0,12	neutral	2,16	deleterious	-5,79	deleterious	-6,15	high_impact	4,6	neutral	0,77	damaging	0,14	deleterious	3,96	23,6	0,06	0,35	disease	0,72	disease	0,84	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	-0,21	high_impact	2,83	0,3	0,8	60,06	10,09	N	0,44	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3758	3758	T	G	MI.11691	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	452	151	L	R	cTa/cGa	-0,7	0	0	probably_damaging	0,99	neutral	0,18	neutral	2,18	deleterious	-4,53	deleterious	-5,31	high_impact	4,6	neutral	0,75	damaging	0,11	deleterious	4,11	23,7	0,05	0,35	disease	0,64	disease	0,88	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-2,62	medium_impact	-0,09	high_impact	2,83	0,13	0,8	60,06	10,09	N	0,46	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3758	3758	T	A	MI.11692	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	452	151	L	Q	cTa/cAa	-0,7	0	0	probably_damaging	1	neutral	0,18	neutral	2,17	deleterious	-5,08	deleterious	-5,28	high_impact	4,6	neutral	0,73	damaging	0,12	deleterious	4,22	23,9	0,07	0,35	disease	0,66	disease	0,78	disease	0,59	disease	0,65	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	-0,09	high_impact	2,83	0,26	0,8	60,06	10,09	N	0,44	N	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3760	3760	T	C	MI.11693	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	454	152	S	P	Tca/Cca	-1,85	0	0	probably_damaging	0,91	neutral	0,11	neutral	2,44	deleterious	-3,81	deleterious	-3,72	medium_impact	2,7	neutral	0,82	neutral	0,47	deleterious	3,91	23,5	0,05	0,35	disease	0,61	disease	0,89	disease	0,6	disease	0,54	1	neutral	0,96	neutral	0,1	deleterious	1	deleterious	0,81	low_impact	-1,69	medium_impact	-0,23	medium_impact	1,17	0,31	0,8	55,03	9,31	N	0,34	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3760	3760	T	G	MI.11694	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	454	152	S	A	Tca/Gca	-1,85	0	0	benign	0,05	neutral	0,32	neutral	2,67	neutral	-0,66	neutral	-1,69	medium_impact	2,06	neutral	0,9	neutral	0,62	deleterious	2,47	19,27	0,31	0,45	neutral	0,23	disease	0,52	neutral	0,34	neutral	0,19	6	neutral	0,65	deleterious	0,64	neutral	-3	neutral	0,19	medium_impact	0,45	medium_impact	0,09	medium_impact	0,61	0,46	0,8	55,03	9,31	N	0,44	N	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3760	3760	T	A	MI.11695	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	454	152	S	T	Tca/Aca	-1,85	0	0	possibly_damaging	0,64	neutral	0,3	neutral	2,52	neutral	-1,93	neutral	-1,84	low_impact	1,82	neutral	0,79	neutral	0,53	deleterious	3,61	23,2	0,31	0,5	neutral	0,25	disease	0,56	neutral	0,34	neutral	0,18	6	neutral	0,74	neutral	0,33	neutral	-3	deleterious	0,55	medium_impact	-0,99	medium_impact	0,07	medium_impact	0,4	0,57	0,8	55,03	9,31	N	0,37	N	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3761	3761	C	G	MI.11696	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	455	152	S	W	tCa/tGa	1,14	0	0	probably_damaging	0,98	neutral	0,09	neutral	2,41	deleterious	-6,43	deleterious	-4,99	high_impact	4,15	neutral	0,67	neutral	0,39	deleterious	4,26	23,9	0,06	0,35	disease	0,81	disease	0,91	disease	0,59	disease	0,68	4	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-2,34	medium_impact	-0,29	high_impact	2,44	0,14	0,8	55,03	9,31	N	0,41	N	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3761	3761	C	T	MI.11697	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	455	152	S	L	tCa/tTa	1,14	0	0	possibly_damaging	0,64	neutral	1	neutral	2,46	deleterious	-3,09	deleterious	-4,12	medium_impact	2,33	neutral	0,7	neutral	0,34	deleterious	4,57	24,4	0,1	0,4	neutral	0,32	disease	0,87	disease	0,51	disease	0,68	4	neutral	0,64	deleterious	0,68	NA	0	deleterious	0,54	medium_impact	-0,99	high_impact	1,96	medium_impact	0,85	0,35	0,8	55,03	9,31	N	0,29	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3763	3763	A	G	MI.11698	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	457	153	T	A	Aca/Gca	-5,07	0	0	benign	0,12	neutral	0,23	neutral	2,8	neutral	-0,12	neutral	-0,88	neutral_impact	0,32	neutral	0,83	neutral	0,77	deleterious	0,26	5,25	0,25	0,45	neutral	0,15	neutral	0,24	neutral	0,34	neutral	0,4	2	neutral	0,74	deleterious	0,56	neutral	-6	neutral	0,1	medium_impact	0,06	medium_impact	-0,02	medium_impact	-0,91	0,36	0,8	22,64	17,03	N	0,4	N	0,28	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3763	3763	A	T	MI.11699	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	457	153	T	S	Aca/Tca	-5,07	0	0	benign	0,3	neutral	0,21	neutral	2,77	neutral	-1,04	neutral	-1,39	neutral_impact	0,18	neutral	0,83	neutral	0,81	neutral	1,47	13,14	0,36	0,5	neutral	0,26	neutral	0,34	neutral	0,34	neutral	0,43	1	neutral	0,75	neutral	0,46	neutral	-6	neutral	0,19	medium_impact	-0,41	medium_impact	-0,05	low_impact	-1,03	0,51	0,8	22,64	17,03	N	0,41	N	0,24	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8581	8581	G	A	MI.117	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	55	19	A	T	Gcc/Acc	-4,73	0	0	probably_damaging	1	neutral	0,06	neutral	4,66	neutral	-0,45	neutral	-0,45	neutral_impact	-0,4	neutral	0,93	neutral	0,86	deleterious	2,81	21,4	0,39	0,65	neutral	0,27	neutral	0,28	neutral	0,22	neutral	0,44	1	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	-0,38	low_impact	-1,44	0,61	0,9	29,65	29,28	N	0,49	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9077	9077	T	G	MI.1170	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	551	184	I	S	aTt/aGt	2,21	0,55	0	benign	0,07	neutral	0,6	neutral	4,55	neutral	-1,9	deleterious	-3,36	neutral_impact	0,28	neutral	0,8	neutral	0,64	neutral	1,29	12,23	0,39	0,65	neutral	0,41	disease	0,59	neutral	0,36	neutral	0,46	1	neutral	0,33	deleterious	0,77	neutral	-6	neutral	0,19	medium_impact	0,31	medium_impact	0,39	medium_impact	-0,86	0,52	0,9	13,72	9,63	N	0,24	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3763	3763	A	C	MI.11700	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	457	153	T	P	Aca/Cca	-5,07	0	0	possibly_damaging	0,71	neutral	0,07	neutral	2,74	neutral	-2,47	deleterious	-2,56	neutral_impact	0,64	neutral	0,64	neutral	0,45	deleterious	1,82	15,1	0,09	0,35	neutral	0,37	disease	0,79	disease	0,62	disease	0,65	3	neutral	0,94	neutral	0,18	neutral	-3	deleterious	0,52	low_impact	-1,12	medium_impact	-0,35	medium_impact	-0,63	0,36	0,8	22,64	17,03	N	0,32	N	0,35	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3764	3764	C	A	MI.11701	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	458	153	T	K	aCa/aAa	-3	0	0	benign	0,41	neutral	0,07	neutral	2,75	neutral	-1,71	neutral	-2,28	medium_impact	2,17	neutral	0,68	neutral	0,52	deleterious	2,71	20,9	0,11	0,4	neutral	0,37	disease	0,69	disease	0,59	disease	0,69	4	neutral	0,92	neutral	0,33	neutral	-3	neutral	0,35	medium_impact	-0,6	medium_impact	-0,35	medium_impact	0,71	0,41	0,8	22,64	17,03	N	0,39	N	0,41	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3764	3764	C	T	MI.11702	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	458	153	T	M	aCa/aTa	-3	0	0	possibly_damaging	0,5	neutral	0,16	neutral	2,79	neutral	-0,26	neutral	0,28	neutral_impact	0,32	neutral	0,83	neutral	0,81	deleterious	0,87	9,9	0,14	0,4	neutral	0,2	neutral	0,33	neutral	0,25	neutral	0,44	1	neutral	0,82	neutral	0,33	neutral	-3	neutral	0,31	medium_impact	-0,75	medium_impact	-0,13	medium_impact	-0,91	0,48	0,8	22,64	17,03	N	0,45	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3766	3766	T	A	MI.11703	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	460	154	L	M	Tta/Ata	-13,34	0	0	probably_damaging	0,98	neutral	0,12	neutral	2,65	neutral	-1,89	neutral	-0,85	neutral_impact	0,74	neutral	0,88	neutral	0,85	deleterious	2,38	18,69	0,32	0,5	neutral	0,41	neutral	0,32	neutral	0,42	neutral	0,46	1	deleterious	0,99	neutral	0,07	neutral	-2	deleterious	0,65	low_impact	-2,34	medium_impact	-0,21	medium_impact	-0,54	0,57	0,8	22,01	23,66	N	0,45	N	0,17	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3766	3766	T	G	MI.11704	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	460	154	L	V	Tta/Gta	-13,34	0	0	possibly_damaging	0,76	neutral	0,17	neutral	2,92	neutral	0,66	neutral	0,23	neutral_impact	0,06	neutral	0,87	neutral	0,64	deleterious	1,83	15,18	0,28	0,45	neutral	0,17	neutral	0,16	neutral	0,23	neutral	0,27	5	neutral	0,88	neutral	0,21	neutral	-3	deleterious	0,48	low_impact	-1,22	medium_impact	-0,11	low_impact	-1,14	0,63	0,8	22,01	23,66	N	0,44	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3767	3767	T	G	MI.11705	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	461	154	L	W	tTa/tGa	-0,7	0	0	probably_damaging	1	deleterious	0,04	neutral	2,59	deleterious	-4,71	deleterious	-4,51	medium_impact	3,41	neutral	0,69	damaging	0,1	deleterious	3,71	23,3	0,07	0,35	disease	0,74	disease	0,68	disease	0,58	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,76	low_impact	-3,57	medium_impact	-0,5	medium_impact	1,79	0,24	0,8	22,01	23,66	N	0,34	N	0,95	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3767	3767	T	C	MI.11706	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	461	154	L	S	tTa/tCa	-0,7	0	0	probably_damaging	0,99	neutral	0,23	neutral	2,65	neutral	-1,81	deleterious	-3,76	medium_impact	1,97	neutral	0,74	damaging	0,15	deleterious	3,77	23,4	0,09	0,35	neutral	0,33	disease	0,56	disease	0,55	disease	0,66	3	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,69	low_impact	-2,62	medium_impact	-0,02	medium_impact	0,53	0,26	0,8	22,01	23,66	N	0,32	N	0,9	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3768	3768	A	T	MI.11707	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	462	154	L	F	ttA/ttT	4,35	0,6	0	probably_damaging	0,98	neutral	0,16	neutral	2,63	neutral	-2,28	neutral	-2,19	low_impact	1,66	neutral	0,8	damaging	0,13	deleterious	3,56	23,1	0,29	0,45	neutral	0,27	disease	0,55	neutral	0,45	neutral	0,42	2	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,65	low_impact	-2,34	medium_impact	-0,13	medium_impact	0,26	0,64	0,8	22,01	23,66	N	0,38	N	0,65	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3768	3768	A	C	MI.11708	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	462	154	L	F	ttA/ttC	4,35	0,6	0	probably_damaging	0,98	neutral	0,16	neutral	2,63	neutral	-2,28	neutral	-2,19	low_impact	1,66	neutral	0,8	damaging	0,13	deleterious	3,42	23	0,29	0,45	neutral	0,27	disease	0,55	neutral	0,45	neutral	0,42	2	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,65	low_impact	-2,34	medium_impact	-0,13	medium_impact	0,26	0,64	0,8	22,01	23,66	N	0,36	N	0,65	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3769	3769	C	G	MI.11709	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	463	155	L	V	Cta/Gta	-3,23	0	0	possibly_damaging	0,9	neutral	0,23	neutral	2,63	neutral	-1,04	neutral	-0,91	low_impact	1,42	neutral	0,8	damaging	0,26	deleterious	2,14	17,09	0,4	0,5	neutral	0,23	neutral	0,29	neutral	0,28	neutral	0,43	1	neutral	0,93	neutral	0,17	neutral	-3	deleterious	0,58	low_impact	-1,65	medium_impact	-0,02	medium_impact	0,05	0,53	0,8	58,81	9,4	N	0,37	N	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	C3769G	LHON (putative)	+	-	Reported	1
chrM	9077	9077	T	A	MI.1171	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	551	184	I	N	aTt/aAt	2,21	0,55	0	benign	0,17	neutral	0,42	neutral	4,5	deleterious	-3,27	deleterious	-4,4	low_impact	1,44	neutral	0,88	neutral	0,48	deleterious	2,59	20,1	0,44	0,65	disease	0,81	disease	0,65	neutral	0,41	disease	0,56	1	neutral	0,5	deleterious	0,63	neutral	-6	neutral	0,4	medium_impact	-0,1	medium_impact	0,21	medium_impact	0,14	0,59	0,9	13,72	9,63	N	0,31	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3769	3769	C	A	MI.11710	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	463	155	L	M	Cta/Ata	-3,23	0	0	possibly_damaging	0,76	neutral	0,18	neutral	2,6	neutral	-1,37	neutral	-0,8	low_impact	0,9	neutral	0,88	neutral	0,84	deleterious	2,39	18,75	0,26	0,45	neutral	0,23	neutral	0,25	neutral	0,27	neutral	0,43	1	neutral	0,88	neutral	0,21	neutral	-3	deleterious	0,53	low_impact	-1,22	medium_impact	-0,09	medium_impact	-0,4	0,49	0,8	58,81	9,4	N	0,47	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3770	3770	T	C	MI.11711	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	464	155	L	P	cTa/cCa	-2,31	0	0	probably_damaging	1	neutral	0,08	neutral	2,46	deleterious	-4,65	deleterious	-5,18	medium_impact	3,4	neutral	0,8	damaging	0,08	deleterious	3,91	23,5	0,02	0,35	disease	0,61	disease	0,84	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,82	low_impact	-3,57	medium_impact	-0,32	medium_impact	1,78	0,21	0,8	58,81	9,4	N	0,27	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3770	3770	T	G	MI.11712	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	464	155	L	R	cTa/cGa	-2,31	0	0	probably_damaging	0,98	deleterious	0,03	neutral	2,47	deleterious	-4,05	deleterious	-4,68	high_impact	3,96	neutral	0,71	damaging	0,07	deleterious	4,13	23,8	0,02	0,35	neutral	0,5	disease	0,83	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,78	low_impact	-2,34	medium_impact	-0,57	high_impact	2,27	0,13	0,8	58,81	9,4	N	0,31	N	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3770	3770	T	A	MI.11713	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	464	155	L	Q	cTa/cAa	-2,31	0	0	probably_damaging	0,99	deleterious	0,03	neutral	2,47	deleterious	-4,11	deleterious	-4,51	high_impact	3,96	neutral	0,76	damaging	0,07	deleterious	4,14	23,8	0,03	0,35	neutral	0,39	disease	0,67	disease	0,55	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,69	low_impact	-2,62	medium_impact	-0,57	high_impact	2,27	0,2	0,8	58,81	9,4	N	0,35	N	0,99	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3772	3772	A	G	MI.11714	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	466	156	M	V	Ata/Gta	-0,93	0	0	possibly_damaging	0,44	neutral	0,16	neutral	2,87	neutral	0,59	neutral	-1,21	low_impact	1,71	neutral	0,83	neutral	0,55	neutral	1,55	13,6	0,29	0,45	neutral	0,12	neutral	0,46	disease	0,59	neutral	0,48	0	neutral	0,82	neutral	0,36	neutral	-3	neutral	0,26	medium_impact	-0,65	medium_impact	-0,13	medium_impact	0,31	0,28	0,8	24,21	24,64	N	0,36	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3772	3772	A	T	MI.11715	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	466	156	M	L	Ata/Tta	-0,93	0	0	benign	0,33	neutral	1	neutral	2,94	neutral	0,89	neutral	0,24	neutral_impact	-0,79	neutral	0,86	neutral	0,95	deleterious	0,58	8,04	0,24	0,45	neutral	0,15	neutral	0,23	neutral	0,3	neutral	0,41	2	neutral	0,33	deleterious	0,84	neutral	-6	neutral	0,17	medium_impact	-0,46	high_impact	1,96	low_impact	-1,88	0,25	0,8	24,21	24,64	N	0,24	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3772	3772	A	C	MI.11716	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	466	156	M	L	Ata/Cta	-0,93	0	0	benign	0,33	neutral	1	neutral	2,94	neutral	0,89	neutral	0,24	neutral_impact	-0,79	neutral	0,86	neutral	0,95	deleterious	0,48	7,28	0,24	0,45	neutral	0,15	neutral	0,23	neutral	0,3	neutral	0,41	2	neutral	0,33	deleterious	0,84	neutral	-6	neutral	0,17	medium_impact	-0,46	high_impact	1,96	low_impact	-1,88	0,25	0,8	24,21	24,64	N	0,23	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3773	3773	T	A	MI.11717	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	467	156	M	K	aTa/aAa	-0,47	0	0	possibly_damaging	0,56	deleterious	0,03	neutral	2,76	neutral	-1,86	deleterious	-3,66	medium_impact	2,85	neutral	0,68	neutral	0,36	deleterious	4,03	23,6	0,04	0,35	neutral	0,4	disease	0,72	disease	0,7	disease	0,7	4	neutral	0,97	neutral	0,24	deleterious	4	deleterious	0,51	medium_impact	-0,85	medium_impact	-0,57	medium_impact	1,3	0,15	0,8	24,21	24,64	N	0,35	N	0,9	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3773	3773	T	C	MI.11718	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	467	156	M	T	aTa/aCa	-0,47	0	0	benign	0,04	neutral	0,07	neutral	2,79	neutral	-0,51	deleterious	-2,79	low_impact	1,69	neutral	0,82	neutral	0,75	deleterious	1,85	15,3	0,17	0,45	neutral	0,24	neutral	0,43	disease	0,61	neutral	0,47	1	neutral	0,93	deleterious	0,52	neutral	-6	neutral	0,14	medium_impact	0,55	medium_impact	-0,35	medium_impact	0,29	0,1	0,8	24,21	24,64	N	0,42	N	0,76	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3774	3774	A	T	MI.11719	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	468	156	M	I	atA/atT	2,98	0,13	0	possibly_damaging	0,44	neutral	0,61	neutral	2,84	neutral	0,06	neutral	-0,47	neutral_impact	0,75	neutral	0,86	neutral	0,95	deleterious	1,84	15,21	0,33	0,5	neutral	0,15	neutral	0,45	neutral	0,38	neutral	0,38	2	neutral	0,38	deleterious	0,59	neutral	-3	neutral	0,33	medium_impact	-0,65	medium_impact	0,38	medium_impact	-0,53	0,23	0,8	24,21	24,64	N	0,33	N	0,29	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9078	9078	T	A	MI.1172	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	552	184	I	M	atT/atA	2,44	0,57	0,01	possibly_damaging	0,54	neutral	0,52	neutral	4,57	neutral	-1,2	neutral	-1,23	neutral_impact	0,28	neutral	0,86	neutral	0,66	neutral	1,7	14,43	0,67	0,75	neutral	0,34	neutral	0,18	neutral	0,3	neutral	0,28	4	neutral	0,52	deleterious	0,49	neutral	-3	neutral	0,4	medium_impact	-0,82	medium_impact	0,31	medium_impact	-0,86	0,75	0,9	13,72	9,63	N	0,31	N	0,8	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3774	3774	A	C	MI.11720	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	468	156	M	I	atA/atC	2,98	0,13	0	possibly_damaging	0,44	neutral	0,61	neutral	2,84	neutral	0,06	neutral	-0,47	neutral_impact	0,75	neutral	0,86	neutral	0,95	neutral	1,76	14,74	0,33	0,5	neutral	0,15	neutral	0,45	neutral	0,38	neutral	0,38	2	neutral	0,38	deleterious	0,59	neutral	-3	neutral	0,33	medium_impact	-0,65	medium_impact	0,38	medium_impact	-0,53	0,23	0,8	24,21	24,64	N	0,33	N	0,29	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3775	3775	A	C	MI.11721	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	469	157	S	R	Agt/Cgt	-1,39	0	0	possibly_damaging	0,66	neutral	0,05	neutral	2,7	neutral	-2,29	neutral	-2,38	medium_impact	3,29	neutral	0,69	neutral	0,45	deleterious	1,87	15,41	0,06	0,35	neutral	0,36	disease	0,78	disease	0,64	disease	0,69	4	neutral	0,95	neutral	0,2	NA	0	deleterious	0,62	low_impact	-1,02	medium_impact	-0,44	medium_impact	1,69	0,4	0,8	17,61	19,73	N	0,45	N	0,71	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3775	3775	A	T	MI.11722	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	469	157	S	C	Agt/Tgt	-1,39	0	0	probably_damaging	0,96	neutral	0,13	neutral	2,65	deleterious	-3,65	deleterious	-2,81	medium_impact	2,43	neutral	0,82	neutral	0,51	deleterious	3,05	22,4	0,13	0,4	disease	0,58	disease	0,65	neutral	0,38	neutral	0,34	3	deleterious	0,98	neutral	0,09	deleterious	1	deleterious	0,71	low_impact	-2,05	medium_impact	-0,19	medium_impact	0,93	0,28	0,8	17,61	19,73	N	0,36	N	0,66	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3775	3775	A	G	MI.11723	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	469	157	S	G	Agt/Ggt	-1,39	0	0	benign	0,4	neutral	0,09	neutral	2,68	neutral	-2,34	neutral	-2,29	medium_impact	2,48	neutral	0,7	neutral	0,53	neutral	1,62	13,97	0,21	0,45	neutral	0,43	neutral	0,42	neutral	0,46	neutral	0,46	1	neutral	0,9	neutral	0,35	neutral	-3	neutral	0,29	medium_impact	-0,59	medium_impact	-0,29	medium_impact	0,98	0,49	0,8	17,61	19,73	N	0,45	N	0,28	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3776	3776	G	C	MI.11724	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	470	157	S	T	aGt/aCt	1,6	0	0	benign	0,4	neutral	0,09	neutral	2,77	neutral	0,03	neutral	0,12	neutral_impact	0,32	neutral	0,76	neutral	0,66	neutral	-0,96	0,02	0,36	0,5	neutral	0,2	neutral	0,1	neutral	0,27	neutral	0,26	5	neutral	0,9	neutral	0,35	neutral	-6	neutral	0,31	medium_impact	-0,59	medium_impact	-0,29	medium_impact	-0,91	0,6	0,8	17,61	19,73	N	0,5	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3776	3776	G	A	MI.11725	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	470	157	S	N	aGt/aAt	1,6	0	0	benign	0,03	neutral	0,14	neutral	2,72	neutral	-2	neutral	-0,48	low_impact	1,26	neutral	0,8	neutral	0,93	neutral	-0,52	0,2	0,54	0,6	neutral	0,26	neutral	0,35	neutral	0,39	neutral	0,43	1	neutral	0,85	deleterious	0,56	neutral	-6	neutral	0,15	medium_impact	0,67	medium_impact	-0,17	medium_impact	-0,09	0,38	0,8	17,61	19,73	N	0,45	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3776	3776	G	T	MI.11726	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	470	157	S	I	aGt/aTt	1,6	0	0	probably_damaging	0,92	neutral	0,48	neutral	2,74	neutral	-1,31	deleterious	-3,14	low_impact	1,27	neutral	0,72	neutral	0,5	deleterious	2,38	18,67	0,1	0,4	neutral	0,23	disease	0,61	neutral	0,34	neutral	0,21	6	neutral	0,91	neutral	0,28	neutral	-2	deleterious	0,63	low_impact	-1,75	medium_impact	0,26	medium_impact	-0,08	0,42	0,8	17,61	19,73	N	0,31	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3778	3778	G	A	MI.11727	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	472	158	G	S	Ggc/Agc	-8,74	0	0	probably_damaging	1	neutral	0,68	neutral	2,6	neutral	-2,31	deleterious	-5,57	medium_impact	2,68	damaging	0,34	damaging	0,03	deleterious	4,16	23,8	0,11	0,4	neutral	0,29	disease	0,7	disease	0,51	neutral	0,17	7	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	0,46	medium_impact	1,15	0,4	0,8	60,06	10,42	N	0,42	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3778	3778	G	T	MI.11728	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	472	158	G	C	Ggc/Tgc	-8,74	0	0	probably_damaging	1	neutral	0,22	neutral	2,5	deleterious	-6,44	deleterious	-8,37	high_impact	3,68	damaging	0,49	damaging	0,01	deleterious	4,2	23,9	0,07	0,35	disease	0,83	disease	0,84	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	-0,03	high_impact	2,03	0,15	0,8	60,06	10,42	N	0,32	N	0,98	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3778	3778	G	C	MI.11729	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	472	158	G	R	Ggc/Cgc	-8,74	0	0	probably_damaging	1	neutral	0,3	neutral	2,55	neutral	-2,73	deleterious	-7,43	medium_impact	3,34	damaging	0,5	damaging	0,01	deleterious	3,97	23,6	0,06	0,35	neutral	0,4	disease	0,85	disease	0,8	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,82	low_impact	-3,57	medium_impact	0,07	medium_impact	1,73	0,52	0,8	60,06	10,42	N	0,38	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9078	9078	T	G	MI.1173	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	552	184	I	M	atT/atG	2,44	0,57	0,01	possibly_damaging	0,54	neutral	0,52	neutral	4,57	neutral	-1,2	neutral	-1,23	neutral_impact	0,28	neutral	0,86	neutral	0,66	neutral	1,47	13,13	0,67	0,75	neutral	0,34	neutral	0,18	neutral	0,3	neutral	0,28	4	neutral	0,52	deleterious	0,49	neutral	-3	neutral	0,4	medium_impact	-0,82	medium_impact	0,31	medium_impact	-0,86	0,75	0,9	13,72	9,63	N	0,32	N	0,8	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3779	3779	G	C	MI.11730	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	473	158	G	A	gGc/gCc	5,96	1	0	probably_damaging	1	neutral	0,48	neutral	2,58	neutral	-2,54	deleterious	-5,57	high_impact	3,77	damaging	0,38	damaging	0,03	deleterious	3,03	22,3	0,12	0,4	neutral	0,36	disease	0,55	disease	0,7	disease	0,65	3	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	0,26	high_impact	2,1	0,34	0,8	60,06	10,42	P	0,68	P	0,76	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3779	3779	G	A	MI.11731	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	473	158	G	D	gGc/gAc	5,96	1	0	probably_damaging	1	neutral	0,17	neutral	2,64	deleterious	-3,03	deleterious	-6,51	medium_impact	3,48	damaging	0,47	damaging	0,01	deleterious	3,78	23,4	0,06	0,35	neutral	0,34	disease	0,83	disease	0,79	disease	0,58	2	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,79	low_impact	-3,57	medium_impact	-0,11	medium_impact	1,85	0,17	0,8	60,06	10,42	P	0,64	P	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3779	3779	G	T	MI.11732	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	473	158	G	V	gGc/gTc	5,96	1	0	probably_damaging	1	neutral	0,7	neutral	2,53	deleterious	-4,03	deleterious	-8,37	high_impact	3,77	damaging	0,43	damaging	0,02	deleterious	3,75	23,3	0,06	0,35	disease	0,53	disease	0,79	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,48	high_impact	2,1	0,15	0,8	60,06	10,42	P	0,62	P	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3781	3781	T	A	MI.11733	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	475	159	S	T	Tcc/Acc	-12,65	0	0	probably_damaging	1	neutral	0,28	neutral	2,55	neutral	-0,82	neutral	-1,95	low_impact	1,9	neutral	0,87	damaging	0,17	deleterious	3,71	23,3	0,26	0,45	neutral	0,23	neutral	0,31	neutral	0,46	neutral	0,43	1	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,69	low_impact	-3,57	medium_impact	0,05	medium_impact	0,47	0,46	0,8	60,69	10,13	N	0,36	N	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3781	3781	T	G	MI.11734	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	475	159	S	A	Tcc/Gcc	-12,65	0	0	probably_damaging	1	neutral	0,33	neutral	2,59	neutral	-2,44	neutral	-1,16	medium_impact	3,4	neutral	0,81	damaging	0,15	deleterious	3,63	23,2	0,21	0,45	neutral	0,33	neutral	0,33	disease	0,62	neutral	0,48	0	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,1	medium_impact	1,78	0,33	0,8	60,69	10,13	N	0,35	N	0,46	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3781	3781	T	C	MI.11735	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	475	159	S	P	Tcc/Ccc	-12,65	0	0	probably_damaging	1	neutral	0,1	neutral	2,5	deleterious	-3,33	deleterious	-2,89	high_impact	3,54	damaging	0,57	damaging	0,04	deleterious	3,96	23,6	0,06	0,35	disease	0,53	disease	0,84	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	-0,26	medium_impact	1,9	0,17	0,8	60,69	10,13	N	0,23	N	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	T3781C	LHON (putative)	+	-	Reported	1
chrM	3782	3782	C	G	MI.11736	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	476	159	S	C	tCc/tGc	2,29	0,92	0	probably_damaging	1	neutral	0,2	neutral	2,48	deleterious	-6,02	deleterious	-3,44	medium_impact	3,19	neutral	0,64	damaging	0,06	deleterious	3,59	23,2	0,08	0,35	disease	0,74	disease	0,7	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,77	low_impact	-3,57	medium_impact	-0,06	medium_impact	1,6	0,28	0,8	60,69	10,13	N	0,39	N	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3782	3782	C	A	MI.11737	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	476	159	S	Y	tCc/tAc	2,29	0,92	0	probably_damaging	1	neutral	0,53	neutral	2,49	deleterious	-4,54	deleterious	-3,72	medium_impact	3,4	neutral	0,69	damaging	0,05	deleterious	4,1	23,7	0,08	0,35	disease	0,6	disease	0,68	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,78	low_impact	-3,57	medium_impact	0,3	medium_impact	1,78	0,23	0,8	60,69	10,13	N	0,38	N	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3782	3782	C	T	MI.11738	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	476	159	S	F	tCc/tTc	2,29	0,92	0	probably_damaging	1	neutral	0,64	neutral	2,49	deleterious	-4,96	deleterious	-3,81	medium_impact	3,4	damaging	0,6	damaging	0,05	deleterious	4,28	24	0,1	0,4	neutral	0,46	disease	0,74	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,42	medium_impact	1,78	0,09	0,8	60,69	10,13	N	0,39	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3784	3784	T	A	MI.11739	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	478	160	F	I	Ttt/Att	-7,59	0	0	probably_damaging	0,91	neutral	0,88	neutral	2,76	neutral	-1	deleterious	-5,41	medium_impact	2,9	neutral	0,72	neutral	0,53	deleterious	4,39	24,1	0,18	0,45	neutral	0,23	disease	0,7	disease	0,66	disease	0,65	3	neutral	0,9	deleterious	0,49	deleterious	1	deleterious	0,7	low_impact	-1,69	medium_impact	0,76	medium_impact	1,34	0,55	0,8	57,86	10,4	N	0,29	N	0,9	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9079	9079	A	T	MI.1174	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	553	185	N	Y	Aac/Tac	-9,13	0	0	possibly_damaging	0,8	neutral	1	neutral	4,46	neutral	-2,34	neutral	-2,31	neutral_impact	0,44	neutral	0,93	neutral	0,77	deleterious	0,86	9,85	0,37	0,65	disease	0,53	neutral	0,48	neutral	0,28	neutral	0,46	1	neutral	0,8	deleterious	0,6	neutral	-3	deleterious	0,64	low_impact	-1,33	high_impact	1,98	medium_impact	-0,72	0,33	0,9	21,24	18,74	N	0,2	N	0,92	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3784	3784	T	G	MI.11740	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	478	160	F	V	Ttt/Gtt	-7,59	0	0	probably_damaging	0,91	neutral	0,68	neutral	2,78	neutral	-0,45	deleterious	-6,26	medium_impact	3,17	neutral	0,69	neutral	0,51	deleterious	4,04	23,7	0,14	0,4	neutral	0,18	disease	0,73	disease	0,72	disease	0,67	3	neutral	0,9	neutral	0,39	deleterious	1	deleterious	0,66	low_impact	-1,69	medium_impact	0,46	medium_impact	1,58	0,38	0,8	57,86	10,4	N	0,31	N	0,89	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3784	3784	T	C	MI.11741	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	478	160	F	L	Ttt/Ctt	-7,59	0	0	possibly_damaging	0,81	neutral	1	neutral	2,86	neutral	1,23	deleterious	-5,4	low_impact	1,84	neutral	0,68	neutral	0,5	deleterious	4	23,6	0,25	0,45	neutral	0,13	disease	0,58	neutral	0,49	neutral	0,17	7	neutral	0,81	deleterious	0,6	neutral	-3	deleterious	0,6	low_impact	-1,34	high_impact	1,96	medium_impact	0,42	0,61	0,8	57,86	10,4	N	0,32	N	0,85	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3785	3785	T	C	MI.11742	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	479	160	F	S	tTt/tCt	7,34	1	0	probably_damaging	0,96	neutral	0,74	neutral	2,71	neutral	-1,49	deleterious	-7,18	high_impact	3,57	neutral	0,7	neutral	0,54	deleterious	4,19	23,9	0,08	0,35	neutral	0,3	disease	0,76	disease	0,69	disease	0,66	3	neutral	0,95	neutral	0,39	deleterious	2	deleterious	0,73	low_impact	-2,05	medium_impact	0,53	medium_impact	1,93	0,22	0,8	57,86	10,4	P	0,54	P	0,98	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3785	3785	T	G	MI.11743	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	479	160	F	C	tTt/tGt	7,34	1	0	probably_damaging	0,99	neutral	0,19	neutral	2,67	deleterious	-3,46	deleterious	-7,19	medium_impact	3,48	neutral	0,72	neutral	0,44	deleterious	4,09	23,7	0,07	0,35	neutral	0,43	disease	0,81	disease	0,73	disease	0,69	4	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,74	low_impact	-2,62	medium_impact	-0,08	medium_impact	1,85	0,2	0,8	57,86	10,4	P	0,61	P	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3785	3785	T	A	MI.11744	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	479	160	F	Y	tTt/tAt	7,34	1	0	benign	0,17	neutral	0,99	neutral	2,72	neutral	-1,97	neutral	-2,26	low_impact	0,91	neutral	0,83	neutral	0,93	deleterious	2,91	21,9	0,22	0,45	neutral	0,25	neutral	0,3	neutral	0,49	neutral	0,39	2	neutral	0,14	deleterious	0,91	neutral	-6	neutral	0,22	medium_impact	-0,1	medium_impact	1,39	medium_impact	-0,39	0,7	0,85	57,86	10,4	N	0,55	P	0,28	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3786	3786	T	A	MI.11745	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	480	160	F	L	ttT/ttA	2,29	0,98	0,01	possibly_damaging	0,81	neutral	1	neutral	2,86	neutral	1,23	deleterious	-5,4	low_impact	1,84	neutral	0,68	neutral	0,5	deleterious	4,39	24,1	0,25	0,45	neutral	0,13	disease	0,58	neutral	0,49	neutral	0,17	7	neutral	0,81	deleterious	0,6	neutral	-3	deleterious	0,6	low_impact	-1,34	high_impact	1,96	medium_impact	0,42	0,61	0,8	57,86	10,4	N	0,44	N	0,85	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3786	3786	T	G	MI.11746	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	480	160	F	L	ttT/ttG	2,29	0,98	0,01	possibly_damaging	0,81	neutral	1	neutral	2,86	neutral	1,23	deleterious	-5,4	low_impact	1,84	neutral	0,68	neutral	0,5	deleterious	4,29	24	0,25	0,45	neutral	0,13	disease	0,58	neutral	0,49	neutral	0,17	7	neutral	0,81	deleterious	0,6	neutral	-3	deleterious	0,6	low_impact	-1,34	high_impact	1,96	medium_impact	0,42	0,61	0,8	57,86	10,4	N	0,44	N	0,85	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3787	3787	A	G	MI.11747	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	481	161	N	D	Aac/Gac	-4,15	0	0	possibly_damaging	0,56	neutral	0,17	neutral	2,6	neutral	-1,05	neutral	-1,45	low_impact	0,9	neutral	0,78	neutral	0,66	deleterious	3,77	23,4	0,53	0,6	neutral	0,34	neutral	0,44	neutral	0,47	neutral	0,42	2	neutral	0,82	neutral	0,31	neutral	-3	neutral	0,4	medium_impact	-0,85	medium_impact	-0,11	medium_impact	-0,4	0,36	0,8	27,36	41,44	N	0,36	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3787	3787	A	C	MI.11748	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	481	161	N	H	Aac/Cac	-4,15	0	0	probably_damaging	0,93	neutral	0,36	neutral	2,57	neutral	-2,73	neutral	-2,25	medium_impact	3,38	neutral	0,72	neutral	0,57	deleterious	3,06	22,4	0,31	0,45	neutral	0,38	neutral	0,48	disease	0,65	disease	0,58	2	neutral	0,93	neutral	0,22	deleterious	1	deleterious	0,63	low_impact	-1,81	medium_impact	0,14	medium_impact	1,76	0,22	0,8	27,36	41,44	N	0,42	N	0,42	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3787	3787	A	T	MI.11749	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	481	161	N	Y	Aac/Tac	-4,15	0	0	probably_damaging	0,95	neutral	0,8	neutral	2,56	deleterious	-3,7	deleterious	-2,81	medium_impact	2,84	neutral	0,71	neutral	0,64	deleterious	3,69	23,3	0,09	0,35	disease	0,58	disease	0,56	disease	0,65	disease	0,68	4	neutral	0,94	neutral	0,43	deleterious	1	deleterious	0,7	low_impact	-1,95	medium_impact	0,61	medium_impact	1,29	0,18	0,8	27,36	41,44	N	0,24	N	0,87	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9079	9079	A	G	MI.1175	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	553	185	N	D	Aac/Gac	-9,13	0	0	benign	0,19	neutral	0,25	neutral	4,39	neutral	-1,8	neutral	-1,55	low_impact	1,2	neutral	0,89	neutral	0,48	deleterious	0,79	9,43	0,66	0,7	disease	0,71	neutral	0,47	neutral	0,49	disease	0,64	3	neutral	0,7	deleterious	0,53	neutral	-6	neutral	0,37	medium_impact	-0,16	medium_impact	0,02	medium_impact	-0,07	0,49	0,9	21,24	18,74	N	0,38	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3788	3788	A	C	MI.11750	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	482	161	N	T	aAc/aCc	1,37	0,25	0	benign	0,06	neutral	0,48	neutral	2,69	neutral	-1,94	neutral	2,27	neutral_impact	-0,1	neutral	0,74	neutral	0,93	deleterious	0,63	8,38	0,27	0,45	neutral	0,24	neutral	0,08	neutral	0,36	neutral	0,26	5	neutral	0,47	deleterious	0,71	neutral	-6	neutral	0,09	medium_impact	0,37	medium_impact	0,26	low_impact	-1,28	0,28	0,8	27,36	41,44	N	0,41	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3788	3788	A	G	MI.11751	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	482	161	N	S	aAc/aGc	1,37	0,25	0	benign	0,06	neutral	0,73	neutral	2,74	neutral	0,39	neutral	0,3	neutral_impact	-0,38	neutral	0,79	neutral	0,98	neutral	1,62	13,95	0,49	0,55	neutral	0,16	neutral	0,21	neutral	0,36	neutral	0,35	3	neutral	0,18	deleterious	0,84	neutral	-6	neutral	0,11	medium_impact	0,37	medium_impact	0,52	low_impact	-1,52	0,18	0,8	27,36	41,44	N	0,29	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3788	3788	A	T	MI.11752	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	482	161	N	I	aAc/aTc	1,37	0,25	0	possibly_damaging	0,78	neutral	1	neutral	2,58	deleterious	-3,54	neutral	-2,3	medium_impact	3,38	neutral	0,83	neutral	0,66	deleterious	3,89	23,5	0,09	0,35	neutral	0,5	disease	0,63	disease	0,61	disease	0,67	3	neutral	0,78	deleterious	0,61	NA	0	deleterious	0,59	low_impact	-1,27	high_impact	1,96	medium_impact	1,76	0,13	0,8	27,36	41,44	N	0,25	N	0,77	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3789	3789	C	A	MI.11753	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	483	161	N	K	aaC/aaA	4,35	0,39	0	possibly_damaging	0,56	neutral	0,22	neutral	2,63	neutral	-1,09	neutral	-1,62	medium_impact	2,29	neutral	0,68	neutral	0,54	deleterious	4,46	24,2	0,37	0,5	neutral	0,24	disease	0,51	disease	0,67	disease	0,58	2	neutral	0,77	neutral	0,33	NA	0	neutral	0,39	medium_impact	-0,85	medium_impact	-0,03	medium_impact	0,81	0,45	0,8	27,36	41,44	N	0,48	N	0,69	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3789	3789	C	G	MI.11754	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	483	161	N	K	aaC/aaG	4,35	0,39	0	possibly_damaging	0,56	neutral	0,22	neutral	2,63	neutral	-1,09	neutral	-1,62	medium_impact	2,29	neutral	0,68	neutral	0,54	deleterious	3,99	23,6	0,37	0,5	neutral	0,24	disease	0,51	disease	0,67	disease	0,58	2	neutral	0,77	neutral	0,33	NA	0	neutral	0,39	medium_impact	-0,85	medium_impact	-0,03	medium_impact	0,81	0,45	0,8	27,36	41,44	N	0,48	N	0,69	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3790	3790	C	G	MI.11755	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	484	162	L	V	Ctc/Gtc	-8,97	0	0	possibly_damaging	0,54	neutral	0,58	neutral	2,72	neutral	-1,82	neutral	-2,46	medium_impact	3,26	neutral	0,71	neutral	0,56	deleterious	3,4	23	0,29	0,45	neutral	0,26	neutral	0,44	disease	0,55	neutral	0,45	1	neutral	0,48	deleterious	0,52	NA	0	neutral	0,43	medium_impact	-0,82	medium_impact	0,35	medium_impact	1,66	0,55	0,8	56,6	8,74	N	0,36	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3790	3790	C	A	MI.11756	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	484	162	L	I	Ctc/Atc	-8,97	0	0	benign	0,15	neutral	0,48	neutral	2,7	neutral	-1,63	neutral	-1,67	medium_impact	2,6	neutral	0,77	neutral	0,64	deleterious	4,2	23,9	0,32	0,5	neutral	0,18	neutral	0,44	neutral	0,38	neutral	0,4	2	neutral	0,43	deleterious	0,67	neutral	-3	neutral	0,2	medium_impact	-0,04	medium_impact	0,26	medium_impact	1,08	0,54	0,8	56,6	8,74	N	0,38	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3790	3790	C	T	MI.11757	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	484	162	L	F	Ctc/Ttc	-8,97	0	0	probably_damaging	0,96	neutral	0,89	neutral	2,67	neutral	-2,52	deleterious	-3,41	medium_impact	2,21	neutral	0,69	neutral	0,53	deleterious	3,94	23,5	0,19	0,45	neutral	0,28	neutral	0,46	neutral	0,43	neutral	0,37	3	neutral	0,95	neutral	0,47	deleterious	1	deleterious	0,69	low_impact	-2,05	medium_impact	0,78	medium_impact	0,74	0,57	0,8	56,6	8,74	N	0,27	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3791	3791	T	G	MI.11758	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	485	162	L	R	cTc/cGc	-0,24	0	0	probably_damaging	0,99	neutral	0,34	neutral	2,6	deleterious	-4,62	deleterious	-5,15	high_impact	4,62	neutral	0,66	neutral	0,36	deleterious	4,2	23,9	0,01	0,35	disease	0,56	disease	0,82	disease	0,75	disease	0,71	4	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-2,62	medium_impact	0,11	high_impact	2,85	0,18	0,8	56,6	8,74	P	0,56	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3791	3791	T	C	MI.11759	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	485	162	L	P	cTc/cCc	-0,24	0	0	probably_damaging	0,99	neutral	0,19	neutral	2,58	deleterious	-3,88	deleterious	-6,05	high_impact	4,07	neutral	0,69	neutral	0,41	deleterious	3,87	23,5	0,01	0,35	disease	0,65	disease	0,77	disease	0,75	disease	0,7	4	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-2,62	medium_impact	-0,08	high_impact	2,37	0,16	0,8	56,6	8,74	N	0,43	N	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9079	9079	A	C	MI.1176	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	553	185	N	H	Aac/Cac	-9,13	0	0	possibly_damaging	0,8	neutral	0,54	neutral	4,37	neutral	-2,55	neutral	-1,41	low_impact	1,2	neutral	0,9	neutral	0,89	neutral	1,07	11,03	0,59	0,7	disease	0,78	neutral	0,4	neutral	0,33	disease	0,66	3	neutral	0,77	neutral	0,37	neutral	-3	deleterious	0,67	low_impact	-1,33	medium_impact	0,33	medium_impact	-0,07	0,46	0,9	21,24	18,74	N	0,31	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3791	3791	T	A	MI.11760	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	485	162	L	H	cTc/cAc	-0,24	0	0	probably_damaging	0,99	neutral	0,52	neutral	2,59	deleterious	-5,15	deleterious	-6,06	high_impact	4,26	neutral	0,7	neutral	0,39	deleterious	4,1	23,7	0,03	0,35	disease	0,65	disease	0,76	disease	0,72	disease	0,68	4	deleterious	0,99	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-2,62	medium_impact	0,29	high_impact	2,53	0,21	0,8	56,6	8,74	N	0,38	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3793	3793	T	C	MI.11761	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	487	163	S	P	Tcc/Ccc	-2,31	0	0	possibly_damaging	0,62	neutral	0,2	neutral	2,69	neutral	-2,81	neutral	-1,41	medium_impact	2,52	neutral	0,89	neutral	0,89	deleterious	2,84	21,6	0,07	0,35	neutral	0,48	disease	0,72	disease	0,54	neutral	0,3	4	neutral	0,81	neutral	0,29	NA	0	deleterious	0,51	medium_impact	-0,95	medium_impact	-0,06	medium_impact	1,01	0,17	0,8	33,33	40,26	N	0,42	N	0,64	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3793	3793	T	G	MI.11762	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	487	163	S	A	Tcc/Gcc	-2,31	0	0	benign	0,18	neutral	0,51	neutral	2,78	neutral	-1,38	neutral	-1,08	medium_impact	2,65	neutral	0,88	neutral	0,85	deleterious	2,51	19,53	0,33	0,5	neutral	0,24	neutral	0,21	neutral	0,36	neutral	0,37	3	neutral	0,39	deleterious	0,67	neutral	-3	neutral	0,16	medium_impact	-0,13	medium_impact	0,29	medium_impact	1,13	0,37	0,8	33,33	40,26	N	0,41	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3793	3793	T	A	MI.11763	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	487	163	S	T	Tcc/Acc	-2,31	0	0	benign	0,02	neutral	0,4	neutral	2,8	neutral	-0,98	neutral	-0,72	low_impact	0,9	neutral	0,85	neutral	0,98	deleterious	2,49	19,42	0,31	0,45	neutral	0,25	neutral	0,16	neutral	0,27	neutral	0,27	5	neutral	0,58	deleterious	0,69	neutral	-6	neutral	0,09	medium_impact	0,84	medium_impact	0,18	medium_impact	-0,4	0,57	0,8	33,33	40,26	N	0,46	N	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3794	3794	C	G	MI.11764	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	488	163	S	C	tCc/tGc	-1,16	0	0	possibly_damaging	0,89	neutral	0,18	neutral	2,68	deleterious	-5,32	deleterious	-2,57	medium_impact	3,07	neutral	0,8	neutral	0,4	deleterious	3,53	23,1	0,11	0,4	disease	0,74	disease	0,54	neutral	0,32	neutral	0,44	1	neutral	0,94	neutral	0,15	NA	0	deleterious	0,67	low_impact	-1,6	medium_impact	-0,09	medium_impact	1,49	0,27	0,8	33,33	40,26	N	0,38	N	0,46	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3794	3794	C	T	MI.11765	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	488	163	S	F	tCc/tTc	-1,16	0	0	benign	0,27	neutral	0,71	neutral	2,72	deleterious	-3,29	neutral	-2,28	low_impact	1,88	neutral	0,86	neutral	0,67	deleterious	3,14	22,6	0,08	0,35	disease	0,6	disease	0,52	neutral	0,32	neutral	0,31	4	neutral	0,2	deleterious	0,72	neutral	-6	neutral	0,3	medium_impact	-0,35	medium_impact	0,49	medium_impact	0,45	0,19	0,8	33,33	40,26	N	0,22	N	0,69	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3794	3794	C	A	MI.11766	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	488	163	S	Y	tCc/tAc	-1,16	0	0	benign	0,02	neutral	1	neutral	2,7	neutral	-2,63	neutral	-0,93	low_impact	1,73	neutral	0,87	neutral	0,74	deleterious	2,83	21,5	0,07	0,35	neutral	0,48	neutral	0,48	neutral	0,29	neutral	0,33	3	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,17	medium_impact	0,84	high_impact	1,96	medium_impact	0,32	0,25	0,8	33,33	40,26	N	0,24	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3796	3796	A	C	MI.11767	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	490	164	T	P	Acc/Ccc	-5,52	0	0,05	possibly_damaging	0,65	neutral	0,2	neutral	2,72	neutral	-2,22	deleterious	-4,32	medium_impact	3,1	neutral	0,6	neutral	0,33	deleterious	3,58	23,2	0,05	0,35	neutral	0,41	disease	0,81	disease	0,51	disease	0,59	2	neutral	0,82	neutral	0,28	NA	0	deleterious	0,52	low_impact	-1	medium_impact	-0,06	medium_impact	1,52	0,42	0,8	32,08	25,47	N	0,37	N	0,79	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3796	3796	A	G	MI.11768	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	490	164	T	A	Acc/Gcc	-5,52	0	0,05	benign	0,02	neutral	0,51	neutral	2,82	neutral	0,15	deleterious	-3,3	low_impact	1,15	neutral	0,91	neutral	0,9	neutral	0,92	10,18	0,29	0,45	neutral	0,19	neutral	0,35	neutral	0,31	neutral	0,43	1	neutral	0,47	deleterious	0,75	neutral	-6	neutral	0,13	medium_impact	0,84	medium_impact	0,29	medium_impact	-0,18	0,46	0,8	32,08	25,47	N	0,38	N	0,01	disease_causing_automatic	0	0,1	rs28357970	Pathogenic,Likely benign	Dystonia,_adult-onset,not_provided	RCV000010382.4,RCV000224953.1	MedGen,MedGen	.	.	CPD	2,67	A3796G	Adult-Onset Dystonia	-	+	Reported	3
chrM	3796	3796	A	T	MI.11769	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	490	164	T	S	Acc/Tcc	-5,52	0	0,05	benign	0,03	neutral	0,41	neutral	2,83	neutral	0,13	neutral	-2,25	neutral_impact	0,69	neutral	0,86	neutral	0,92	deleterious	0,67	8,63	0,3	0,45	neutral	0,17	neutral	0,35	neutral	0,21	neutral	0,44	1	neutral	0,57	deleterious	0,69	neutral	-6	neutral	0,13	medium_impact	0,67	medium_impact	0,19	medium_impact	-0,59	0,55	0,8	32,08	25,47	N	0,3	N	0,21	disease_causing_automatic	0	0,04	rs28357970	Pathogenic,Likely benign	Dystonia,_adult-onset,not_provided	RCV000010382.4,RCV000224953.1	MedGen,MedGen	.	.	.	.	.	.	.	.	.	.
chrM	9080	9080	A	G	MI.1177	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	554	185	N	S	aAc/aGc	2,67	0,01	0	benign	0,01	neutral	0,54	neutral	4,51	neutral	-0,79	neutral	0,25	neutral_impact	-1,3	neutral	0,88	neutral	0,98	neutral	-1,02	0,01	0,68	0,75	neutral	0,43	neutral	0,16	neutral	0,23	neutral	0,31	4	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,13	medium_impact	1,14	medium_impact	0,33	low_impact	-2,21	0,23	0,9	21,24	18,74	N	0,36	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3797	3797	C	T	MI.11770	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	491	164	T	I	aCc/aTc	0,45	0	0	benign	0,36	neutral	0,4	neutral	2,73	neutral	-2,4	deleterious	-4,19	medium_impact	1,98	neutral	0,7	neutral	0,54	deleterious	2,28	18,02	0,18	0,45	neutral	0,39	disease	0,68	neutral	0,37	neutral	0,33	3	neutral	0,53	deleterious	0,52	neutral	-3	neutral	0,32	medium_impact	-0,52	medium_impact	0,18	medium_impact	0,54	0,58	0,8	32,08	25,47	N	0,34	N	0,61	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3797	3797	C	A	MI.11771	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	491	164	T	N	aCc/aAc	0,45	0	0	benign	0,36	neutral	0,31	neutral	2,77	neutral	-0,81	deleterious	-2,66	neutral_impact	0,6	neutral	0,87	neutral	0,92	deleterious	1,85	15,28	0,42	0,55	neutral	0,18	neutral	0,42	neutral	0,23	neutral	0,43	1	neutral	0,63	deleterious	0,48	neutral	-6	neutral	0,27	medium_impact	-0,52	medium_impact	0,08	medium_impact	-0,66	0,61	0,8	32,08	25,47	N	0,41	N	0,33	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3797	3797	C	G	MI.11772	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	491	164	T	S	aCc/aGc	0,45	0	0	benign	0,03	neutral	0,41	neutral	2,83	neutral	0,13	neutral	-2,25	neutral_impact	0,69	neutral	0,86	neutral	0,92	deleterious	0,39	6,5	0,3	0,45	neutral	0,17	neutral	0,35	neutral	0,21	neutral	0,44	1	neutral	0,57	deleterious	0,69	neutral	-6	neutral	0,13	medium_impact	0,67	medium_impact	0,19	medium_impact	-0,59	0,55	0,8	32,08	25,47	N	0,4	N	0,21	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3799	3799	C	A	MI.11773	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	493	165	L	I	Ctt/Att	-6,9	0	0	probably_damaging	1	neutral	0,41	neutral	2,87	neutral	2,09	neutral	-0,74	neutral_impact	0,5	neutral	0,75	damaging	0,13	deleterious	4,09	23,7	0,3	0,45	neutral	0,13	neutral	0,36	neutral	0,28	neutral	0,42	2	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,68	low_impact	-3,57	medium_impact	0,19	medium_impact	-0,75	0,61	0,8	54,09	8,52	N	0,3	N	0,83	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3799	3799	C	G	MI.11774	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	493	165	L	V	Ctt/Gtt	-6,9	0	0	probably_damaging	1	neutral	0,52	neutral	2,69	neutral	-0,2	neutral	-1,61	low_impact	1,57	neutral	0,92	neutral	0,73	deleterious	3,44	23	0,31	0,5	neutral	0,22	neutral	0,45	neutral	0,32	neutral	0,45	1	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,68	low_impact	-3,57	medium_impact	0,29	medium_impact	0,18	0,54	0,8	54,09	8,52	N	0,33	N	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3799	3799	C	T	MI.11775	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	493	165	L	F	Ctt/Ttt	-6,9	0	0	probably_damaging	1	neutral	0,75	neutral	2,64	neutral	-1,48	neutral	1,55	neutral_impact	-0,28	neutral	0,83	neutral	0,63	neutral	1,22	11,87	0,26	0,45	neutral	0,25	neutral	0,06	neutral	0,22	neutral	0,24	5	deleterious	1	neutral	0,38	neutral	-2	deleterious	0,66	low_impact	-3,57	medium_impact	0,54	low_impact	-1,43	0,58	0,8	54,09	8,52	N	0,27	N	0,95	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3800	3800	T	C	MI.11776	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	494	165	L	P	cTt/cCt	0,45	0,18	0	probably_damaging	1	neutral	0,21	neutral	2,54	deleterious	-3,68	deleterious	-4,79	medium_impact	3,27	neutral	0,79	damaging	0,1	deleterious	3,85	23,4	0,02	0,35	disease	0,61	disease	0,87	disease	0,68	disease	0,75	5	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,87	low_impact	-3,57	medium_impact	-0,05	medium_impact	1,67	0,2	0,8	54,09	8,52	N	0,28	N	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3800	3800	T	G	MI.11777	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	494	165	L	R	cTt/cGt	0,45	0,18	0	probably_damaging	1	neutral	0,34	neutral	2,55	deleterious	-3,1	deleterious	-3,87	high_impact	3,62	neutral	0,64	damaging	0,09	deleterious	4,18	23,8	0,01	0,35	disease	0,52	disease	0,87	disease	0,67	disease	0,75	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,11	medium_impact	1,97	0,19	0,8	54,09	8,52	N	0,31	N	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3800	3800	T	A	MI.11778	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	494	165	L	H	cTt/cAt	0,45	0,18	0	probably_damaging	1	neutral	0,54	neutral	2,54	deleterious	-3,64	deleterious	-3,23	high_impact	3,62	neutral	0,71	damaging	0,1	deleterious	4,07	23,7	0,02	0,35	disease	0,6	disease	0,72	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,31	medium_impact	1,97	0,24	0,8	54,09	8,52	N	0,25	N	0,97	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3802	3802	A	T	MI.11779	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	496	166	I	F	Atc/Ttc	-3,92	0	0	probably_damaging	0,98	neutral	0,71	neutral	2,78	neutral	-1,35	neutral	-1,16	low_impact	0,92	neutral	0,75	neutral	0,38	neutral	1,57	13,7	0,2	0,45	neutral	0,22	neutral	0,39	neutral	0,25	neutral	0,43	1	neutral	0,97	neutral	0,37	neutral	-2	deleterious	0,62	low_impact	-2,34	medium_impact	0,49	medium_impact	-0,39	0,68	0,85	22,64	17,53	N	0,25	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9080	9080	A	T	MI.1178	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	554	185	N	I	aAc/aTc	2,67	0,01	0	possibly_damaging	0,74	neutral	0,41	neutral	4,42	neutral	-1,58	deleterious	-2,51	neutral_impact	-0,24	neutral	0,84	neutral	0,71	deleterious	2,03	16,39	0,35	0,65	disease	0,55	disease	0,55	neutral	0,25	neutral	0,47	1	neutral	0,75	neutral	0,34	neutral	-3	deleterious	0,58	low_impact	-1,19	medium_impact	0,2	low_impact	-1,3	0,31	0,9	21,24	18,74	N	0,29	N	0,9	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3802	3802	A	G	MI.11780	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	496	166	I	V	Atc/Gtc	-3,92	0	0	possibly_damaging	0,83	neutral	0,51	neutral	2,95	neutral	2,2	neutral	-0,15	neutral_impact	0,72	neutral	0,82	neutral	0,68	neutral	1,16	11,52	0,55	0,6	neutral	0,12	neutral	0,09	neutral	0,27	neutral	0,26	5	neutral	0,81	neutral	0,34	neutral	-3	deleterious	0,51	low_impact	-1,4	medium_impact	0,29	medium_impact	-0,56	0,59	0,8	22,64	17,53	N	0,36	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3802	3802	A	C	MI.11781	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	496	166	I	L	Atc/Ctc	-3,92	0	0	possibly_damaging	0,78	neutral	0,66	neutral	2,84	neutral	0,05	neutral	-0,19	low_impact	1	neutral	0,82	neutral	0,68	neutral	1,61	13,93	0,26	0,45	neutral	0,17	neutral	0,26	neutral	0,3	neutral	0,42	2	neutral	0,73	neutral	0,44	neutral	-3	deleterious	0,52	low_impact	-1,27	medium_impact	0,44	medium_impact	-0,32	0,64	0,8	22,64	17,53	N	0,31	N	0,58	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3803	3803	T	C	MI.11782	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	497	166	I	T	aTc/aCc	1,6	0	0	possibly_damaging	0,83	neutral	0,4	neutral	2,77	neutral	-0,9	neutral	0,26	neutral_impact	0,63	neutral	0,83	neutral	0,92	neutral	1,68	14,29	0,11	0,4	neutral	0,22	neutral	0,19	neutral	0,28	neutral	0,34	3	neutral	0,84	neutral	0,29	neutral	-3	deleterious	0,54	low_impact	-1,4	medium_impact	0,18	medium_impact	-0,64	0,35	0,8	22,64	17,53	N	0,42	N	0,7	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3803	3803	T	G	MI.11783	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	497	166	I	S	aTc/aGc	1,6	0	0	possibly_damaging	0,83	neutral	0,41	neutral	2,77	neutral	-1,13	neutral	0,62	neutral_impact	0,58	neutral	0,8	neutral	0,81	deleterious	2,44	19,07	0,07	0,35	neutral	0,2	neutral	0,27	neutral	0,3	neutral	0,43	2	neutral	0,83	neutral	0,29	neutral	-3	deleterious	0,52	low_impact	-1,4	medium_impact	0,19	medium_impact	-0,68	0,21	0,8	22,64	17,53	N	0,34	N	0,7	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3803	3803	T	A	MI.11784	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	497	166	I	N	aTc/aAc	1,6	0	0	benign	0,12	neutral	0,32	neutral	2,74	neutral	-1,87	neutral	0,78	neutral_impact	0,25	neutral	0,83	neutral	0,9	deleterious	2,6	20,2	0,15	0,4	neutral	0,35	neutral	0,26	neutral	0,28	neutral	0,45	1	neutral	0,63	deleterious	0,6	neutral	-6	neutral	0,16	medium_impact	0,06	medium_impact	0,09	medium_impact	-0,97	0,23	0,8	22,64	17,53	N	0,45	N	0,88	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3804	3804	C	A	MI.11785	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	498	166	I	M	atC/atA	-0,24	0	0	probably_damaging	0,98	neutral	0,22	neutral	2,77	neutral	-1,28	neutral	0,22	low_impact	0,8	neutral	0,86	neutral	0,87	deleterious	2,36	18,56	0,37	0,5	neutral	0,29	neutral	0,15	neutral	0,25	neutral	0,29	4	deleterious	0,98	neutral	0,12	neutral	-2	deleterious	0,62	low_impact	-2,34	medium_impact	-0,03	medium_impact	-0,49	0,77	0,85	22,64	17,53	N	0,46	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3804	3804	C	G	MI.11786	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	498	166	I	M	atC/atG	-0,24	0	0	probably_damaging	0,98	neutral	0,22	neutral	2,77	neutral	-1,28	neutral	0,22	low_impact	0,8	neutral	0,86	neutral	0,87	deleterious	1,91	15,67	0,37	0,5	neutral	0,29	neutral	0,15	neutral	0,25	neutral	0,29	4	deleterious	0,98	neutral	0,12	neutral	-2	deleterious	0,62	low_impact	-2,34	medium_impact	-0,03	medium_impact	-0,49	0,77	0,85	22,64	17,53	N	0,45	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3805	3805	A	G	MI.11787	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	499	167	T	A	Aca/Gca	-3,69	0	0	benign	0,36	neutral	0,49	neutral	2,8	neutral	0,5	neutral	-2,01	low_impact	1,46	neutral	0,86	neutral	0,79	deleterious	2,35	18,47	0,27	0,45	neutral	0,15	neutral	0,34	neutral	0,27	neutral	0,44	1	neutral	0,43	deleterious	0,57	neutral	-6	neutral	0,24	medium_impact	-0,52	medium_impact	0,27	medium_impact	0,09	0,31	0,8	22,96	18,52	N	0,32	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3805	3805	A	T	MI.11788	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	499	167	T	S	Aca/Tca	-3,69	0	0	possibly_damaging	0,48	neutral	0,51	neutral	2,81	neutral	-0,17	neutral	-2,04	low_impact	0,89	neutral	0,83	neutral	0,92	deleterious	2,19	17,43	0,32	0,5	neutral	0,19	neutral	0,34	neutral	0,25	neutral	0,44	1	neutral	0,48	deleterious	0,52	neutral	-3	neutral	0,38	medium_impact	-0,72	medium_impact	0,29	medium_impact	-0,41	0,49	0,8	22,96	18,52	N	0,32	N	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3805	3805	A	C	MI.11789	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	499	167	T	P	Aca/Cca	-3,69	0	0	possibly_damaging	0,87	neutral	0,16	neutral	2,73	neutral	-2,28	deleterious	-3,41	medium_impact	2,81	neutral	0,82	neutral	0,44	deleterious	3,44	23	0,05	0,35	neutral	0,44	disease	0,8	neutral	0,43	disease	0,61	2	neutral	0,93	neutral	0,15	NA	0	deleterious	0,68	low_impact	-1,53	medium_impact	-0,13	medium_impact	1,27	0,32	0,8	22,96	18,52	N	0,33	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9080	9080	A	C	MI.1179	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	554	185	N	T	aAc/aCc	2,67	0,01	0	benign	0,19	neutral	0,45	neutral	4,47	neutral	-1,1	neutral	-1,06	neutral_impact	0,57	neutral	0,91	neutral	0,87	deleterious	-0,03	2,35	0,56	0,65	disease	0,61	neutral	0,26	neutral	0,39	disease	0,56	1	neutral	0,46	deleterious	0,63	neutral	-6	neutral	0,27	medium_impact	-0,16	medium_impact	0,24	medium_impact	-0,61	0,41	0,9	21,24	18,74	N	0,4	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3806	3806	C	A	MI.11790	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	500	167	T	K	aCa/aAa	-0,47	0	0	benign	0,04	neutral	0,3	neutral	2,82	neutral	-0,04	deleterious	-3,25	low_impact	1,16	neutral	0,76	neutral	0,55	deleterious	4,41	24,1	0,1	0,4	neutral	0,19	disease	0,61	neutral	0,23	neutral	0,22	6	neutral	0,68	deleterious	0,63	neutral	-6	neutral	0,15	medium_impact	0,55	medium_impact	0,07	medium_impact	-0,18	0,33	0,8	22,96	18,52	N	0,41	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3806	3806	C	T	MI.11791	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	500	167	T	M	aCa/aTa	-0,47	0	0	benign	0,25	neutral	0,29	neutral	2,74	neutral	-2,12	neutral	-1,55	neutral_impact	0,68	neutral	0,88	neutral	0,88	deleterious	2,94	22	0,15	0,4	neutral	0,34	neutral	0,39	neutral	0,19	neutral	0,46	1	neutral	0,65	deleterious	0,52	neutral	-6	neutral	0,23	medium_impact	-0,3	medium_impact	0,06	medium_impact	-0,59	0,39	0,8	22,96	18,52	N	0,51	P	0,8	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3808	3808	A	C	MI.11792	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	502	168	T	P	Aca/Cca	-8,05	0	0	probably_damaging	0,96	neutral	0,2	neutral	2,7	neutral	-2,47	deleterious	-4,11	medium_impact	3,08	neutral	0,61	neutral	0,31	neutral	1,53	13,46	0,05	0,35	disease	0,51	disease	0,82	disease	0,68	disease	0,72	4	neutral	0,97	neutral	0,12	deleterious	1	deleterious	0,76	low_impact	-2,05	medium_impact	-0,06	medium_impact	1,5	0,4	0,8	55,35	8,8	N	0,31	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3808	3808	A	T	MI.11793	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	502	168	T	S	Aca/Tca	-8,05	0	0	possibly_damaging	0,74	neutral	0,49	neutral	2,78	neutral	0,29	neutral	-2,17	neutral_impact	0,54	neutral	0,85	neutral	0,84	neutral	1,56	13,61	0,28	0,45	neutral	0,24	neutral	0,39	neutral	0,42	neutral	0,44	1	neutral	0,72	neutral	0,38	neutral	-3	deleterious	0,52	low_impact	-1,18	medium_impact	0,27	medium_impact	-0,72	0,61	0,8	55,35	8,8	N	0,31	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3808	3808	A	G	MI.11794	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	502	168	T	A	Aca/Gca	-8,05	0	0	benign	0,08	neutral	0,53	neutral	2,88	neutral	1,38	neutral	-2,24	neutral_impact	0,49	neutral	0,91	neutral	0,61	deleterious	0,18	4,42	0,26	0,45	neutral	0,13	neutral	0,14	neutral	0,41	neutral	0,24	5	neutral	0,4	deleterious	0,73	neutral	-6	neutral	0,12	medium_impact	0,25	medium_impact	0,3	medium_impact	-0,76	0,23	0,8	55,35	8,8	N	0,28	N	0,65	polymorphism	1	0,08	rs2854135	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3809	3809	C	T	MI.11795	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	503	168	T	M	aCa/aTa	0,91	0,28	0	probably_damaging	0,98	neutral	0,28	neutral	2,72	neutral	-1,04	deleterious	-4	low_impact	1,86	neutral	0,7	neutral	0,48	deleterious	3,87	23,5	0,14	0,4	neutral	0,44	disease	0,57	neutral	0,48	neutral	0,48	0	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,7	low_impact	-2,34	medium_impact	0,05	medium_impact	0,44	0,58	0,8	55,35	8,8	N	0,37	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3809	3809	C	A	MI.11796	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	503	168	T	K	aCa/aAa	0,91	0,28	0	possibly_damaging	0,83	neutral	0,38	neutral	2,77	neutral	-0,39	deleterious	-4,05	medium_impact	2,52	neutral	0,69	neutral	0,34	deleterious	2,8	21,4	0,07	0,35	neutral	0,25	disease	0,73	disease	0,61	disease	0,67	3	neutral	0,84	neutral	0,28	NA	0	deleterious	0,68	low_impact	-1,4	medium_impact	0,16	medium_impact	1,01	0,33	0,8	55,35	8,8	N	0,32	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3811	3811	C	G	MI.11797	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	505	169	Q	E	Caa/Gaa	-6,21	0	0	probably_damaging	1	neutral	0,32	neutral	2,59	neutral	-2,47	deleterious	-2,76	high_impact	3,66	neutral	0,72	damaging	0,12	deleterious	3,08	22,5	0,24	0,45	neutral	0,32	disease	0,63	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,09	high_impact	2,01	0,28	0,8	58,49	10,49	N	0,42	N	0,93	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3811	3811	C	A	MI.11798	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	505	169	Q	K	Caa/Aaa	-6,21	0	0	probably_damaging	1	neutral	0,34	neutral	2,58	neutral	-2,54	deleterious	-3,68	high_impact	3,78	neutral	0,69	damaging	0,1	deleterious	3,97	23,6	0,14	0,4	neutral	0,34	disease	0,72	disease	0,8	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,11	high_impact	2,11	0,21	0,8	58,49	10,49	N	0,41	N	0,98	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3812	3812	A	T	MI.11799	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	506	169	Q	L	cAa/cTa	5,5	1	0	probably_damaging	1	neutral	0,69	neutral	2,49	deleterious	-4,01	deleterious	-6,45	high_impact	3,78	neutral	0,67	damaging	0,08	deleterious	3,61	23,2	0,06	0,35	neutral	0,34	disease	0,8	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,47	high_impact	2,11	0,1	0,8	58,49	10,49	N	0,5	N	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8581	8581	G	T	MI.118	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	55	19	A	S	Gcc/Tcc	-4,73	0	0	probably_damaging	0,99	deleterious	0,02	neutral	4,65	neutral	-1,02	neutral	-1,23	neutral_impact	0,11	neutral	0,79	neutral	0,65	deleterious	3,51	23,1	0,29	0,65	neutral	0,33	neutral	0,41	neutral	0,24	neutral	0,48	0	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,71	low_impact	-2,65	medium_impact	-0,66	low_impact	-1	0,58	0,9	29,65	29,28	N	0,38	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9081	9081	C	G	MI.1180	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	555	185	N	K	aaC/aaG	-0,33	0	0	benign	0,28	neutral	0,36	neutral	4,42	neutral	-1,06	neutral	-1,53	low_impact	1	neutral	0,89	neutral	0,48	deleterious	0,79	9,42	0,68	0,75	disease	0,54	neutral	0,5	neutral	0,5	disease	0,51	0	neutral	0,56	deleterious	0,54	neutral	-6	neutral	0,38	medium_impact	-0,37	medium_impact	0,15	medium_impact	-0,24	0,47	0,9	21,24	18,74	N	0,33	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3812	3812	A	G	MI.11800	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	506	169	Q	R	cAa/cGa	5,5	1	0	probably_damaging	1	neutral	0,37	neutral	2,53	deleterious	-3,06	deleterious	-3,68	high_impact	4,01	neutral	0,71	damaging	0,1	deleterious	3,34	22,9	0,15	0,4	neutral	0,42	disease	0,74	disease	0,81	disease	0,72	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,15	high_impact	2,31	0,16	0,8	58,49	10,49	P	0,69	P	0,95	polymorphism	0,98	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3812	3812	A	C	MI.11801	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	506	169	Q	P	cAa/cCa	5,5	1	0	probably_damaging	1	neutral	0,21	neutral	2,47	deleterious	-4,18	deleterious	-5,53	high_impact	3,92	neutral	0,69	damaging	0,1	deleterious	3,19	22,7	0,05	0,35	disease	0,63	disease	0,77	disease	0,81	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,05	high_impact	2,24	0,14	0,8	58,49	10,49	P	0,67	P	0,98	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3813	3813	A	T	MI.11802	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	507	169	Q	H	caA/caT	8,49	1	0	probably_damaging	1	neutral	0,54	neutral	2,49	deleterious	-4,1	deleterious	-4,61	high_impact	4,27	neutral	0,66	damaging	0,09	deleterious	3,58	23,2	0,15	0,4	disease	0,59	disease	0,72	disease	0,81	disease	0,73	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	0,31	high_impact	2,54	0,38	0,8	58,49	10,49	P	0,67	P	0,98	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3813	3813	A	C	MI.11803	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	507	169	Q	H	caA/caC	8,49	1	0	probably_damaging	1	neutral	0,54	neutral	2,49	deleterious	-4,1	deleterious	-4,61	high_impact	4,27	neutral	0,66	damaging	0,09	deleterious	3,41	23	0,15	0,4	disease	0,59	disease	0,72	disease	0,81	disease	0,73	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	0,31	high_impact	2,54	0,38	0,8	58,49	10,49	P	0,67	P	0,98	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3814	3814	G	A	MI.11804	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	508	170	E	K	Gaa/Aaa	2,52	1	0	probably_damaging	1	neutral	0,37	neutral	2,77	neutral	-0,23	deleterious	-3,5	low_impact	1,72	neutral	0,79	neutral	0,44	deleterious	4,44	24,2	0,13	0,4	neutral	0,19	disease	0,51	neutral	0,34	neutral	0,41	2	deleterious	1	neutral	0,19	neutral	-2	deleterious	0,72	low_impact	-3,57	medium_impact	0,15	medium_impact	0,31	0,51	0,8	57,23	9,28	N	0,47	N	0,47	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3814	3814	G	C	MI.11805	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	508	170	E	Q	Gaa/Caa	2,52	1	0	probably_damaging	1	neutral	0,37	neutral	2,72	neutral	-0,04	deleterious	-2,65	low_impact	1,04	neutral	0,79	damaging	0,23	deleterious	3,32	22,9	0,43	0,55	neutral	0,26	neutral	0,46	neutral	0,26	neutral	0,42	2	deleterious	1	neutral	0,19	neutral	-2	deleterious	0,7	low_impact	-3,57	medium_impact	0,15	medium_impact	-0,28	0,63	0,8	57,23	9,28	N	0,42	N	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3815	3815	A	T	MI.11806	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	509	170	E	V	gAa/gTa	5,96	1	0	probably_damaging	1	neutral	0,56	neutral	2,69	neutral	-1,77	deleterious	-6,37	medium_impact	2,48	neutral	0,69	damaging	0,12	deleterious	4,04	23,7	0,15	0,45	neutral	0,28	disease	0,62	disease	0,57	disease	0,64	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	0,33	medium_impact	0,98	0,39	0,8	57,23	9,28	N	0,46	N	0,93	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3815	3815	A	G	MI.11807	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	509	170	E	G	gAa/gGa	5,96	1	0	probably_damaging	1	neutral	0,37	neutral	2,68	neutral	-1,18	deleterious	-6,36	medium_impact	2,44	neutral	0,75	damaging	0,15	deleterious	4,16	23,8	0,22	0,45	neutral	0,21	neutral	0,49	neutral	0,49	neutral	0,43	1	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,15	medium_impact	0,94	0,28	0,8	57,23	9,28	P	0,56	P	0,83	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3815	3815	A	C	MI.11808	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	509	170	E	A	gAa/gCa	5,96	1	0	probably_damaging	1	neutral	0,56	neutral	2,76	neutral	0	deleterious	-5,44	medium_impact	2,31	neutral	0,75	damaging	0,14	deleterious	3,6	23,2	0,28	0,45	neutral	0,22	neutral	0,5	disease	0,54	disease	0,6	2	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	0,33	medium_impact	0,83	0,31	0,8	57,23	9,28	N	0,49	N	0,79	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3816	3816	A	C	MI.11809	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	510	170	E	D	gaA/gaC	8,49	1	0	probably_damaging	1	neutral	0,27	neutral	2,71	neutral	-0,94	deleterious	-2,74	medium_impact	2,74	neutral	0,76	damaging	0,11	deleterious	3,66	23,2	0,44	0,55	neutral	0,29	neutral	0,48	neutral	0,25	neutral	0,46	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,03	medium_impact	1,2	0,59	0,8	57,23	9,28	P	0,6	P	0,9	polymorphism	1	0,07	rs386828924	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9081	9081	C	A	MI.1181	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	555	185	N	K	aaC/aaA	-0,33	0	0	benign	0,28	neutral	0,36	neutral	4,42	neutral	-1,06	neutral	-1,53	low_impact	1	neutral	0,89	neutral	0,48	neutral	1,26	12,09	0,68	0,75	disease	0,54	neutral	0,5	neutral	0,5	disease	0,51	0	neutral	0,56	deleterious	0,54	neutral	-6	neutral	0,38	medium_impact	-0,37	medium_impact	0,15	medium_impact	-0,24	0,47	0,9	21,24	18,74	N	0,34	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3816	3816	A	T	MI.11810	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	510	170	E	D	gaA/gaT	8,49	1	0	probably_damaging	1	neutral	0,27	neutral	2,71	neutral	-0,94	deleterious	-2,74	medium_impact	2,74	neutral	0,76	damaging	0,11	deleterious	3,73	23,3	0,44	0,55	neutral	0,29	neutral	0,48	neutral	0,25	neutral	0,46	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,03	medium_impact	1,2	0,59	0,8	57,23	9,28	P	0,61	P	0,9	polymorphism	1	0,07	rs386828924	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3817	3817	C	T	MI.11811	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	511	171	H	Y	Cac/Tac	-0,01	0	0,01	benign	0	neutral	1	neutral	2,81	neutral	-1,55	neutral	-0,85	neutral_impact	-0,28	neutral	0,83	neutral	0,96	neutral	-0,78	0,05	0,25	0,45	neutral	0,17	neutral	0,11	neutral	0,29	neutral	0,24	5	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,07	high_impact	1,96	low_impact	-1,43	0,24	0,8	24,84	26,33	N	0,33	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3817	3817	C	G	MI.11812	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	511	171	H	D	Cac/Gac	-0,01	0	0,01	benign	0,11	neutral	0,21	neutral	2,81	neutral	-0,75	neutral	-1,39	low_impact	1,15	neutral	0,77	neutral	0,47	deleterious	0,63	8,38	0,08	0,35	neutral	0,14	neutral	0,27	neutral	0,5	neutral	0,42	2	neutral	0,76	deleterious	0,55	neutral	-6	neutral	0,14	medium_impact	0,1	medium_impact	-0,05	medium_impact	-0,18	0,41	0,8	24,84	26,33	N	0,39	N	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3817	3817	C	A	MI.11813	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	511	171	H	N	Cac/Aac	-0,01	0	0,01	benign	0,01	neutral	0,34	neutral	2,82	neutral	-0,33	neutral	-0,38	neutral_impact	-0,43	neutral	0,84	neutral	0,92	deleterious	0,17	4,36	0,28	0,45	neutral	0,15	neutral	0,15	neutral	0,38	neutral	0,3	4	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,11	low_impact	-1,56	0,37	0,8	24,84	26,33	N	0,39	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3818	3818	A	C	MI.11814	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	512	171	H	P	cAc/cCc	-1,85	0	0	possibly_damaging	0,49	neutral	0,2	neutral	2,8	neutral	-1,08	neutral	-0,88	neutral_impact	0,54	neutral	0,84	neutral	0,9	neutral	-0,27	0,77	0,08	0,35	neutral	0,26	neutral	0,42	disease	0,56	neutral	0,46	1	neutral	0,78	neutral	0,36	neutral	-3	neutral	0,34	medium_impact	-0,74	medium_impact	-0,06	medium_impact	-0,72	0,29	0,8	24,84	26,33	N	0,39	N	0,97	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3818	3818	A	G	MI.11815	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	512	171	H	R	cAc/cGc	-1,85	0	0	benign	0,01	neutral	0,34	neutral	2,83	neutral	-0,9	neutral	-1,42	low_impact	1,52	neutral	0,9	neutral	0,68	neutral	-0,62	0,11	0,14	0,4	neutral	0,19	neutral	0,25	neutral	0,42	neutral	0,43	2	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,11	medium_impact	0,14	0,21	0,8	24,84	26,33	N	0,46	N	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3818	3818	A	T	MI.11816	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	512	171	H	L	cAc/cTc	-1,85	0	0	benign	0,11	neutral	0,66	neutral	2,9	neutral	-1,45	neutral	-2,35	neutral_impact	0,32	neutral	0,88	neutral	0,89	neutral	-0,14	1,43	0,1	0,4	neutral	0,21	neutral	0,29	neutral	0,43	neutral	0,42	2	neutral	0,23	deleterious	0,78	neutral	-6	neutral	0,15	medium_impact	0,1	medium_impact	0,44	medium_impact	-0,91	0,17	0,8	24,84	26,33	N	0,31	N	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3819	3819	C	G	MI.11817	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	513	171	H	Q	caC/caG	0,45	0	0	benign	0,01	neutral	0,34	neutral	2,85	neutral	-0,5	neutral	-0,84	neutral_impact	0,19	neutral	0,85	neutral	0,92	deleterious	0,16	4,29	0,22	0,45	neutral	0,14	neutral	0,13	neutral	0,35	neutral	0,31	4	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,11	low_impact	-1,02	0,34	0,8	24,84	26,33	N	0,45	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3819	3819	C	A	MI.11818	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	513	171	H	Q	caC/caA	0,45	0	0	benign	0,01	neutral	0,34	neutral	2,85	neutral	-0,5	neutral	-0,84	neutral_impact	0,19	neutral	0,85	neutral	0,92	deleterious	0,5	7,43	0,22	0,45	neutral	0,14	neutral	0,13	neutral	0,35	neutral	0,31	4	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,11	low_impact	-1,02	0,34	0,8	24,84	26,33	N	0,45	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3820	3820	C	G	MI.11819	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	514	172	L	V	Ctc/Gtc	-6,21	0	0	benign	0,07	neutral	0,54	neutral	2,8	neutral	-0,78	neutral	0,25	low_impact	0,94	neutral	0,84	neutral	0,96	neutral	-0,25	0,86	0,35	0,5	neutral	0,17	neutral	0,07	neutral	0,25	neutral	0,24	5	neutral	0,4	deleterious	0,74	neutral	-6	neutral	0,13	medium_impact	0,3	medium_impact	0,31	medium_impact	-0,37	0,46	0,8	20,13	21,45	N	0,4	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9082	9082	C	G	MI.1182	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	556	186	L	V	Ctt/Gtt	-1,49	0	0	benign	0,32	neutral	0,52	neutral	4,35	neutral	-0,57	neutral	-0,29	neutral_impact	0,12	neutral	0,94	neutral	0,86	deleterious	0,47	7,16	0,48	0,65	neutral	0,32	neutral	0,33	neutral	0,34	neutral	0,46	1	neutral	0,39	deleterious	0,6	neutral	-6	neutral	0,4	medium_impact	-0,45	medium_impact	0,31	medium_impact	-1	0,59	0,9	28,32	18,04	N	0,31	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3820	3820	C	T	MI.11820	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	514	172	L	F	Ctc/Ttc	-6,21	0	0	benign	0,02	neutral	0,74	neutral	2,7	neutral	-2,07	neutral	-1,69	low_impact	1,49	neutral	0,84	neutral	0,78	neutral	0,93	10,28	0,24	0,45	neutral	0,34	neutral	0,22	neutral	0,37	neutral	0,4	2	neutral	0,22	deleterious	0,86	neutral	-6	neutral	0,15	medium_impact	0,84	medium_impact	0,53	medium_impact	0,11	0,48	0,8	20,13	21,45	N	0,28	N	0,28	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3820	3820	C	A	MI.11821	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	514	172	L	I	Ctc/Atc	-6,21	0	0	benign	0,01	neutral	0,42	neutral	2,78	neutral	-0,83	neutral	0,38	neutral_impact	-0,26	neutral	0,78	neutral	0,96	neutral	-0,46	0,28	0,32	0,5	neutral	0,17	neutral	0,03	neutral	0,2	neutral	0,19	6	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,2	low_impact	-1,42	0,42	0,8	20,13	21,45	N	0,48	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3821	3821	T	C	MI.11822	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	515	172	L	P	cTc/cCc	-1,62	0	0	possibly_damaging	0,66	neutral	0,25	neutral	2,67	neutral	-2,92	deleterious	-3,19	low_impact	1,64	neutral	0,69	neutral	0,37	deleterious	2,02	16,31	0,02	0,35	disease	0,6	disease	0,65	disease	0,7	disease	0,73	5	neutral	0,78	neutral	0,3	neutral	-3	deleterious	0,59	low_impact	-1,02	medium_impact	0,01	medium_impact	0,24	0,11	0,8	20,13	21,45	N	0,29	N	0,72	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3821	3821	T	G	MI.11823	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	515	172	L	R	cTc/cGc	-1,62	0	0	possibly_damaging	0,47	neutral	0,43	neutral	2,7	deleterious	-3,03	deleterious	-2,91	medium_impact	2,8	neutral	0,73	neutral	0,46	deleterious	2,29	18,11	0,02	0,35	neutral	0,42	disease	0,56	disease	0,71	disease	0,72	4	neutral	0,54	deleterious	0,48	NA	0	deleterious	0,47	medium_impact	-0,7	medium_impact	0,21	medium_impact	1,26	0,2	0,8	20,13	21,45	N	0,32	N	0,37	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3821	3821	T	A	MI.11824	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	515	172	L	H	cTc/cAc	-1,62	0	0	possibly_damaging	0,67	neutral	0,54	neutral	2,68	neutral	-2,9	deleterious	-3,37	medium_impact	1,94	neutral	0,74	neutral	0,62	deleterious	3,6	23,2	0,05	0,35	neutral	0,43	neutral	0,37	disease	0,67	neutral	0,5	0	neutral	0,63	neutral	0,44	NA	0	deleterious	0,44	low_impact	-1,04	medium_impact	0,31	medium_impact	0,51	0,15	0,8	20,13	21,45	N	0,28	N	0,46	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3823	3823	T	G	MI.11825	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	517	173	W	G	Tga/Gga	-7,13	0	0	probably_damaging	1	neutral	0,33	neutral	2,41	deleterious	-4,05	deleterious	-11,24	high_impact	3,69	neutral	0,78	damaging	0,12	deleterious	3,86	23,5	0,05	0,35	disease	0,68	disease	0,67	disease	0,81	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,1	high_impact	2,03	0,07	0,8	58,49	10,4	N	0,37	N	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3823	3823	T	C	MI.11826	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	517	173	W	R	Tga/Cga	-7,13	0	0	probably_damaging	1	neutral	0,34	neutral	2,42	deleterious	-3,44	deleterious	-11,98	high_impact	4,67	neutral	0,7	damaging	0,09	deleterious	3,55	23,1	0,03	0,35	disease	0,65	disease	0,79	disease	0,85	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,11	high_impact	2,89	0,09	0,8	58,49	10,4	N	0,55	P	0,98	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3824	3824	G	T	MI.11827	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	518	173	W	L	tGa/tTa	4,58	1	0	probably_damaging	1	neutral	0,67	neutral	2,49	neutral	-2,09	deleterious	-11,01	medium_impact	2,62	neutral	0,76	damaging	0,1	deleterious	4,28	24	0,07	0,35	neutral	0,28	disease	0,71	disease	0,78	disease	0,68	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	0,45	medium_impact	1,1	0,08	0,8	58,49	10,4	N	0,44	N	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3824	3824	G	C	MI.11828	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	518	173	W	S	tGa/tCa	4,58	1	0	probably_damaging	1	neutral	0,43	neutral	2,43	deleterious	-3,08	deleterious	-11,97	medium_impact	3,15	neutral	0,79	damaging	0,13	deleterious	4,09	23,7	0,05	0,35	neutral	0,45	disease	0,74	disease	0,77	disease	0,58	2	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,77	low_impact	-3,57	medium_impact	0,21	medium_impact	1,56	0,08	0,8	58,49	10,4	N	0,48	N	0,99	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3825	3825	A	C	MI.11829	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	519	173	W	C	tgA/tgC	4,81	1	0	probably_damaging	1	neutral	0,18	neutral	2,39	deleterious	-5,05	deleterious	-11,13	medium_impact	3,47	neutral	0,74	damaging	0,09	deleterious	4,02	23,6	0,04	0,35	disease	0,74	disease	0,76	disease	0,79	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,79	low_impact	-3,57	medium_impact	-0,09	medium_impact	1,84	0,1	0,8	58,49	10,4	P	0,56	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9082	9082	C	T	MI.1183	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	556	186	L	F	Ctt/Ttt	-1,49	0	0	possibly_damaging	0,81	neutral	0,7	neutral	4,33	neutral	-1,46	neutral	-1,45	neutral_impact	0,68	neutral	0,93	neutral	0,9	deleterious	2,57	19,89	0,45	0,65	disease	0,68	neutral	0,47	neutral	0,22	disease	0,59	2	neutral	0,77	neutral	0,45	neutral	-3	deleterious	0,7	low_impact	-1,35	medium_impact	0,5	medium_impact	-0,52	0,59	0,9	28,32	18,04	N	0,28	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3825	3825	A	T	MI.11830	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	519	173	W	C	tgA/tgT	4,81	1	0	probably_damaging	1	neutral	0,18	neutral	2,39	deleterious	-5,05	deleterious	-11,13	medium_impact	3,47	neutral	0,74	damaging	0,09	deleterious	4,1	23,7	0,04	0,35	disease	0,74	disease	0,76	disease	0,79	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,79	low_impact	-3,57	medium_impact	-0,09	medium_impact	1,84	0,1	0,8	58,49	10,4	P	0,56	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3826	3826	T	G	MI.11831	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	520	174	L	V	Tta/Gta	1,83	0,91	0	possibly_damaging	0,74	neutral	0,52	neutral	2,74	neutral	-1,16	deleterious	-2,56	medium_impact	2,54	neutral	0,79	neutral	0,54	deleterious	3,39	23	0,27	0,45	neutral	0,27	neutral	0,33	disease	0,56	neutral	0,46	1	neutral	0,72	neutral	0,39	NA	0	deleterious	0,54	low_impact	-1,18	medium_impact	0,29	medium_impact	1,03	0,62	0,8	55,03	9,73	N	0,36	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3826	3826	T	A	MI.11832	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	520	174	L	M	Tta/Ata	1,83	0,91	0	possibly_damaging	0,52	neutral	0,23	neutral	2,67	neutral	-2,3	neutral	-1,46	medium_impact	1,94	neutral	0,85	neutral	0,86	deleterious	2,54	19,7	0,24	0,45	neutral	0,39	neutral	0,27	neutral	0,3	neutral	0,46	1	neutral	0,75	neutral	0,36	NA	0	deleterious	0,43	medium_impact	-0,78	medium_impact	-0,02	medium_impact	0,51	0,49	0,8	55,03	9,73	N	0,46	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3827	3827	T	C	MI.11833	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	521	174	L	S	tTa/tCa	-1,85	0	0	probably_damaging	0,94	neutral	0,44	neutral	2,73	neutral	-2,05	deleterious	-5,21	medium_impact	2,54	neutral	0,7	neutral	0,55	deleterious	3,77	23,4	0,05	0,35	neutral	0,34	neutral	0,5	disease	0,59	disease	0,63	3	neutral	0,94	neutral	0,25	deleterious	1	deleterious	0,68	low_impact	-1,87	medium_impact	0,22	medium_impact	1,03	0,28	0,8	55,03	9,73	N	0,3	N	0,97	polymorphism	1	0,12	rs879048761	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3827	3827	T	G	MI.11834	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	521	174	L	W	tTa/tGa	-1,85	0	0	probably_damaging	0,98	neutral	0,19	neutral	2,64	deleterious	-3,35	deleterious	-5,14	medium_impact	2,98	neutral	0,68	neutral	0,41	deleterious	3,75	23,3	0,06	0,35	disease	0,74	disease	0,61	disease	0,61	disease	0,65	3	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,77	low_impact	-2,34	medium_impact	-0,08	medium_impact	1,41	0,26	0,8	55,03	9,73	N	0,31	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3828	3828	A	C	MI.11835	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	522	174	L	F	ttA/ttC	7,34	0,95	0	benign	0,17	neutral	0,71	neutral	2,72	neutral	-0,93	deleterious	-3,27	low_impact	0,82	neutral	0,83	neutral	0,84	deleterious	2,33	18,35	0,25	0,45	neutral	0,25	neutral	0,09	neutral	0,24	neutral	0,28	4	neutral	0,17	deleterious	0,77	neutral	-6	neutral	0,19	medium_impact	-0,1	medium_impact	0,49	medium_impact	-0,47	0,56	0,8	55,03	9,73	P	0,54	P	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3828	3828	A	T	MI.11836	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	522	174	L	F	ttA/ttT	7,34	0,95	0	benign	0,17	neutral	0,71	neutral	2,72	neutral	-0,93	deleterious	-3,27	low_impact	0,82	neutral	0,83	neutral	0,84	deleterious	2,47	19,27	0,25	0,45	neutral	0,25	neutral	0,09	neutral	0,24	neutral	0,28	4	neutral	0,17	deleterious	0,77	neutral	-6	neutral	0,19	medium_impact	-0,1	medium_impact	0,49	medium_impact	-0,47	0,56	0,8	55,03	9,73	P	0,55	P	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3829	3829	C	T	MI.11837	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	523	175	L	F	Ctc/Ttc	-5,52	0	0	benign	0,02	neutral	0,7	neutral	2,64	neutral	-1,41	neutral	-2,4	low_impact	1,24	neutral	0,88	neutral	0,87	neutral	0,97	10,47	0,22	0,45	neutral	0,36	neutral	0,29	neutral	0,29	neutral	0,46	1	neutral	0,26	deleterious	0,84	neutral	-6	neutral	0,17	medium_impact	0,84	medium_impact	0,48	medium_impact	-0,11	0,54	0,8	19,81	23,12	N	0,31	N	0,37	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3829	3829	C	A	MI.11838	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	523	175	L	I	Ctc/Atc	-5,52	0	0	benign	0,01	neutral	0,4	neutral	2,78	neutral	0,02	neutral	0,12	neutral_impact	-0,5	neutral	0,77	neutral	0,94	neutral	-0,57	0,15	0,27	0,45	neutral	0,14	neutral	0,05	neutral	0,18	neutral	0,21	6	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,18	low_impact	-1,63	0,46	0,8	19,81	23,12	N	0,5	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3829	3829	C	G	MI.11839	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	523	175	L	V	Ctc/Gtc	-5,52	0	0	benign	0,06	neutral	0,5	neutral	2,76	neutral	-0,67	neutral	-0,52	low_impact	0,92	neutral	0,9	neutral	0,94	deleterious	0,25	5,19	0,27	0,45	neutral	0,25	neutral	0,2	neutral	0,26	neutral	0,36	3	neutral	0,44	deleterious	0,72	neutral	-6	neutral	0,15	medium_impact	0,37	medium_impact	0,28	medium_impact	-0,39	0,62	0,8	19,81	23,12	N	0,44	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9082	9082	C	A	MI.1184	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	556	186	L	I	Ctt/Att	-1,49	0	0	possibly_damaging	0,51	neutral	0,4	neutral	4,3	neutral	-0,7	neutral	-0,42	neutral_impact	0,22	neutral	0,91	neutral	0,95	neutral	1,42	12,88	0,42	0,65	neutral	0,33	neutral	0,26	neutral	0,17	neutral	0,46	1	neutral	0,58	neutral	0,45	neutral	-3	deleterious	0,5	medium_impact	-0,77	medium_impact	0,19	medium_impact	-0,91	0,62	0,9	28,32	18,04	N	0,48	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3830	3830	T	C	MI.11840	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	524	175	L	P	cTc/cCc	-2,77	0	0	possibly_damaging	0,84	neutral	0,21	neutral	2,61	deleterious	-3,51	deleterious	-4,89	medium_impact	2,67	neutral	0,62	neutral	0,4	deleterious	3,56	23,1	0,04	0,35	disease	0,51	disease	0,77	disease	0,68	disease	0,72	4	neutral	0,9	neutral	0,19	NA	0	deleterious	0,71	low_impact	-1,43	medium_impact	-0,05	medium_impact	1,14	0,33	0,8	19,81	23,12	N	0,33	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3830	3830	T	A	MI.11841	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	524	175	L	H	cTc/cAc	-2,77	0	0	possibly_damaging	0,88	neutral	0,54	neutral	2,61	deleterious	-4,06	deleterious	-4,95	high_impact	3,56	neutral	0,72	neutral	0,51	deleterious	3,97	23,6	0,05	0,35	disease	0,64	disease	0,58	disease	0,64	disease	0,68	4	neutral	0,87	neutral	0,33	deleterious	1	deleterious	0,71	low_impact	-1,56	medium_impact	0,31	medium_impact	1,92	0,26	0,8	19,81	23,12	N	0,31	N	0,82	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3830	3830	T	G	MI.11842	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	524	175	L	R	cTc/cGc	-2,77	0	0	possibly_damaging	0,78	neutral	0,35	neutral	2,63	deleterious	-3,1	deleterious	-4,5	medium_impact	3,22	neutral	0,68	neutral	0,47	deleterious	2,57	19,9	0,03	0,35	disease	0,55	disease	0,77	disease	0,67	disease	0,72	4	neutral	0,8	neutral	0,29	NA	0	deleterious	0,66	low_impact	-1,27	medium_impact	0,12	medium_impact	1,62	0,28	0,8	19,81	23,12	N	0,33	N	0,92	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3832	3832	C	G	MI.11843	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	526	176	L	V	Ctg/Gtg	-9,89	0	0	benign	0,32	neutral	0,5	neutral	2,72	neutral	-0,85	neutral	-1,03	low_impact	0,93	neutral	0,87	neutral	0,98	deleterious	2,07	16,68	0,23	0,45	neutral	0,18	neutral	0,13	neutral	0,27	neutral	0,3	4	neutral	0,41	deleterious	0,59	neutral	-6	neutral	0,21	medium_impact	-0,44	medium_impact	0,28	medium_impact	-0,38	0,5	0,8	27,36	28,35	N	0,44	N	0,37	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3832	3832	C	A	MI.11844	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	526	176	L	M	Ctg/Atg	-9,89	0	0	probably_damaging	0,9	neutral	0,22	neutral	2,61	neutral	-2,91	neutral	-0,88	low_impact	1,92	neutral	0,89	neutral	0,93	deleterious	2,63	20,4	0,23	0,45	neutral	0,34	neutral	0,13	neutral	0,26	neutral	0,31	4	neutral	0,94	neutral	0,16	neutral	-2	deleterious	0,58	low_impact	-1,65	medium_impact	-0,03	medium_impact	0,49	0,34	0,8	27,36	28,35	P	0,55	P	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3833	3833	T	G	MI.11845	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	527	176	L	R	cTg/cGg	-5,75	0	0	probably_damaging	0,9	neutral	0,32	neutral	2,57	deleterious	-3,64	deleterious	-4,05	high_impact	3,72	neutral	0,73	neutral	0,47	deleterious	4,19	23,8	0,02	0,35	neutral	0,47	disease	0,66	disease	0,68	disease	0,68	4	neutral	0,92	neutral	0,21	deleterious	2	deleterious	0,71	low_impact	-1,65	medium_impact	0,09	high_impact	2,06	0,25	0,8	27,36	28,35	N	0,43	N	0,89	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3833	3833	T	A	MI.11846	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	527	176	L	Q	cTg/cAg	-5,75	0	0	probably_damaging	0,93	neutral	0,36	neutral	2,57	deleterious	-4	deleterious	-3,98	high_impact	3,72	neutral	0,74	neutral	0,52	deleterious	4,19	23,8	0,03	0,35	neutral	0,48	neutral	0,43	disease	0,53	neutral	0,46	1	neutral	0,93	neutral	0,22	deleterious	2	deleterious	0,66	low_impact	-1,81	medium_impact	0,14	high_impact	2,06	0,33	0,8	27,36	28,35	N	0,48	N	0,83	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	T3833A	PEG	+	-	Reported	1
chrM	3833	3833	T	C	MI.11847	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	527	176	L	P	cTg/cCg	-5,75	0	0	probably_damaging	0,93	neutral	0,2	neutral	2,56	deleterious	-3,39	deleterious	-4,64	medium_impact	3,17	neutral	0,68	neutral	0,39	deleterious	3,91	23,5	0,02	0,35	neutral	0,39	disease	0,68	disease	0,68	disease	0,68	4	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,69	low_impact	-1,81	medium_impact	-0,06	medium_impact	1,58	0,28	0,8	27,36	28,35	N	0,37	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3835	3835	C	G	MI.11848	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	529	177	P	A	Cca/Gca	-8,74	0	0	possibly_damaging	0,9	neutral	0,51	neutral	2,82	neutral	-1,73	deleterious	-4,61	medium_impact	2,7	neutral	0,8	damaging	0,21	deleterious	3,05	22,4	0,22	0,45	neutral	0,2	neutral	0,37	neutral	0,49	neutral	0,42	2	neutral	0,89	neutral	0,31	NA	0	deleterious	0,63	low_impact	-1,65	medium_impact	0,29	medium_impact	1,17	0,75	0,85	19,18	20,15	N	0,26	N	0,64	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3835	3835	C	T	MI.11849	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	529	177	P	S	Cca/Tca	-8,74	0	0	possibly_damaging	0,52	neutral	0,45	neutral	2,8	neutral	-2,46	deleterious	-4,24	low_impact	1,62	neutral	0,84	neutral	0,84	deleterious	2,64	20,5	0,28	0,45	neutral	0,21	neutral	0,28	neutral	0,37	neutral	0,41	2	neutral	0,55	neutral	0,47	neutral	-3	neutral	0,42	medium_impact	-0,78	medium_impact	0,23	medium_impact	0,23	0,23	0,8	19,18	20,15	N	0,35	N	0,33	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9083	9083	T	C	MI.1185	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	557	186	L	P	cTt/cCt	-1,49	0	0	benign	0,01	neutral	0,3	neutral	4,25	deleterious	-3,76	neutral	1,35	neutral_impact	-1,4	neutral	0,92	neutral	0,96	neutral	-0,76	0,05	0,16	0,65	neutral	0,47	neutral	0,15	neutral	0,29	neutral	0,23	6	neutral	0,69	deleterious	0,65	neutral	-6	neutral	0,18	medium_impact	1,14	medium_impact	0,08	low_impact	-2,3	0,56	0,9	28,32	18,04	N	0,38	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3835	3835	C	A	MI.11850	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	529	177	P	T	Cca/Aca	-8,74	0	0	probably_damaging	0,94	neutral	0,42	neutral	2,78	neutral	-2,31	deleterious	-4,4	medium_impact	1,97	neutral	0,87	neutral	0,86	deleterious	2,54	19,71	0,22	0,45	neutral	0,19	neutral	0,38	neutral	0,38	neutral	0,41	2	neutral	0,94	neutral	0,24	deleterious	1	deleterious	0,64	low_impact	-1,87	medium_impact	0,2	medium_impact	0,53	0,73	0,85	19,18	20,15	N	0,4	N	0,41	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3836	3836	C	A	MI.11851	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	530	177	P	Q	cCa/cAa	-0,01	0	0	probably_damaging	0,98	neutral	0,33	neutral	2,76	neutral	-2,88	deleterious	-4,96	high_impact	3,71	neutral	0,76	damaging	0,11	deleterious	4,04	23,7	0,12	0,4	neutral	0,27	disease	0,56	disease	0,56	disease	0,6	2	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,67	low_impact	-2,34	medium_impact	0,1	high_impact	2,05	0,41	0,8	19,18	20,15	N	0,35	N	0,74	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3836	3836	C	G	MI.11852	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	530	177	P	R	cCa/cGa	-0,01	0	0	probably_damaging	0,98	neutral	0,34	neutral	2,81	deleterious	-3,16	deleterious	-5,75	high_impact	3,51	neutral	0,7	damaging	0,1	deleterious	3,56	23,1	0,08	0,35	neutral	0,25	disease	0,7	disease	0,67	disease	0,65	3	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,71	low_impact	-2,34	medium_impact	0,11	medium_impact	1,88	0,47	0,8	19,18	20,15	N	0,28	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3836	3836	C	T	MI.11853	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	530	177	P	L	cCa/cTa	-0,01	0	0	probably_damaging	0,98	neutral	0,73	neutral	2,8	neutral	-1,18	deleterious	-6,27	low_impact	1,58	neutral	0,74	damaging	0,1	deleterious	4,41	24,1	0,13	0,4	neutral	0,15	disease	0,53	neutral	0,35	neutral	0,22	6	neutral	0,98	neutral	0,38	neutral	-2	deleterious	0,66	low_impact	-2,34	medium_impact	0,52	medium_impact	0,19	0,64	0,8	19,18	20,15	N	0,19	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3838	3838	T	G	MI.11854	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	532	178	S	A	Tca/Gca	-5,07	0	0	benign	0,02	neutral	0,56	neutral	2,81	neutral	0,07	neutral	-0,05	neutral_impact	0,71	neutral	0,85	neutral	0,98	neutral	-0,94	0,02	0,32	0,5	neutral	0,15	neutral	0,15	neutral	0,29	neutral	0,24	5	neutral	0,42	deleterious	0,77	neutral	-6	neutral	0,13	medium_impact	0,84	medium_impact	0,33	medium_impact	-0,57	0,57	0,8	22,01	19,27	N	0,33	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3838	3838	T	C	MI.11855	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	532	178	S	P	Tca/Cca	-5,07	0	0	possibly_damaging	0,74	neutral	0,3	neutral	2,72	neutral	-2,06	deleterious	-2,78	medium_impact	2,08	neutral	0,78	neutral	0,37	deleterious	2,09	16,8	0,07	0,35	neutral	0,48	disease	0,83	disease	0,56	disease	0,67	3	neutral	0,8	neutral	0,28	NA	0	deleterious	0,6	low_impact	-1,18	medium_impact	0,07	medium_impact	0,63	0,38	0,8	22,01	19,27	N	0,4	N	0,55	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3838	3838	T	A	MI.11856	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	532	178	S	T	Tca/Aca	-5,07	0	0	benign	0,03	neutral	0,39	neutral	2,78	neutral	-0,35	neutral	-0,83	neutral_impact	0,75	neutral	0,8	neutral	0,99	deleterious	-0,03	2,33	0,26	0,45	neutral	0,18	neutral	0,21	neutral	0,28	neutral	0,36	3	neutral	0,59	deleterious	0,68	neutral	-6	neutral	0,13	medium_impact	0,67	medium_impact	0,17	medium_impact	-0,53	0,57	0,8	22,01	19,27	N	0,44	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3839	3839	C	G	MI.11857	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	533	178	S	W	tCa/tGa	-2,54	0	0	probably_damaging	0,92	neutral	0,34	neutral	2,7	deleterious	-3,77	deleterious	-4,3	medium_impact	2,73	neutral	0,73	neutral	0,39	deleterious	2,67	20,6	0,07	0,35	disease	0,7	disease	0,82	disease	0,53	disease	0,68	4	neutral	0,93	neutral	0,21	deleterious	1	deleterious	0,73	low_impact	-1,75	medium_impact	0,11	medium_impact	1,2	0,17	0,8	22,01	19,27	N	0,3	N	0,68	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3839	3839	C	T	MI.11858	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	533	178	S	L	tCa/tTa	-2,54	0	0	benign	0,35	neutral	0,78	neutral	2,81	neutral	0,06	deleterious	-3	neutral_impact	-0,06	neutral	0,89	neutral	0,88	neutral	1,57	13,66	0,11	0,4	neutral	0,14	disease	0,55	neutral	0,32	neutral	0,24	5	neutral	0,24	deleterious	0,72	neutral	-6	neutral	0,24	medium_impact	-0,5	medium_impact	0,58	low_impact	-1,24	0,44	0,8	22,01	19,27	N	0,26	N	0,64	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3841	3841	T	C	MI.11859	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	535	179	W	R	Tga/Cga	-5,52	0	0	probably_damaging	1	neutral	0,22	neutral	2,79	neutral	-2,28	deleterious	-12,54	high_impact	4,03	neutral	0,73	damaging	0,09	deleterious	3,55	23,1	0,06	0,35	neutral	0,36	disease	0,81	disease	0,77	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	-0,03	high_impact	2,33	0,15	0,8	60,06	10,44	N	0,48	N	0,98	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9083	9083	T	A	MI.1186	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	557	186	L	H	cTt/cAt	-1,49	0	0	possibly_damaging	0,9	neutral	0,53	neutral	4,22	deleterious	-4,32	neutral	-1,87	low_impact	1,3	neutral	0,8	neutral	0,52	deleterious	2,95	22	0,23	0,65	disease	0,75	disease	0,6	neutral	0,5	disease	0,51	0	neutral	0,88	neutral	0,32	neutral	-3	deleterious	0,76	low_impact	-1,66	medium_impact	0,32	medium_impact	0,02	0,52	0,9	28,32	18,04	N	0,24	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3841	3841	T	G	MI.11860	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	535	179	W	G	Tga/Gga	-5,52	0	0	probably_damaging	1	neutral	0,25	neutral	2,78	neutral	-1,81	deleterious	-11,7	medium_impact	3,22	neutral	0,75	damaging	0,11	deleterious	3,92	23,5	0,08	0,35	neutral	0,26	disease	0,64	disease	0,73	disease	0,67	3	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,01	medium_impact	1,62	0,15	0,8	60,06	10,44	N	0,35	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3842	3842	G	C	MI.11861	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	536	179	W	S	tGa/tCa	7,34	1	0	probably_damaging	1	neutral	0,43	neutral	2,82	neutral	-1,23	deleterious	-12,54	medium_impact	2,53	neutral	0,75	damaging	0,13	deleterious	3,99	23,6	0,08	0,35	neutral	0,24	disease	0,71	disease	0,71	disease	0,68	4	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,21	medium_impact	1,02	0,15	0,8	60,06	10,44	N	0,47	N	0,99	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3842	3842	G	T	MI.11862	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	536	179	W	L	tGa/tTa	7,34	1	0	probably_damaging	1	neutral	1	neutral	2,99	neutral	0,69	deleterious	-11,46	low_impact	1,77	neutral	0,76	damaging	0,14	deleterious	4,19	23,8	0,11	0,4	neutral	0,16	disease	0,58	disease	0,55	neutral	0,26	5	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,68	low_impact	-3,57	high_impact	1,96	medium_impact	0,36	0,12	0,8	60,06	10,44	N	0,4	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3843	3843	A	C	MI.11863	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	537	179	W	C	tgA/tgC	7,11	1	0	probably_damaging	1	neutral	0,14	neutral	2,78	deleterious	-3,13	deleterious	-11,61	medium_impact	3,22	neutral	0,74	damaging	0,11	deleterious	3,96	23,6	0,07	0,35	neutral	0,43	disease	0,76	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	-0,17	medium_impact	1,62	0,2	0,8	60,06	10,44	P	0,53	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3843	3843	A	T	MI.11864	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	537	179	W	C	tgA/tgT	7,11	1	0	probably_damaging	1	neutral	0,14	neutral	2,78	deleterious	-3,13	deleterious	-11,61	medium_impact	3,22	neutral	0,74	damaging	0,11	deleterious	4,1	23,7	0,07	0,35	neutral	0,43	disease	0,76	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	-0,17	medium_impact	1,62	0,2	0,8	60,06	10,44	P	0,54	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3844	3844	C	T	MI.11865	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	538	180	P	S	Ccc/Tcc	0,68	0,99	0	probably_damaging	1	neutral	0,32	neutral	2,65	deleterious	-3,45	deleterious	-7,38	high_impact	3,66	neutral	0,72	damaging	0,12	deleterious	3,93	23,5	0,16	0,45	neutral	0,39	disease	0,6	disease	0,61	disease	0,63	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,72	low_impact	-3,57	medium_impact	0,09	high_impact	2,01	0,19	0,8	60,69	10,4	N	0,43	N	0,74	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3844	3844	C	A	MI.11866	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	538	180	P	T	Ccc/Acc	0,68	0,99	0	probably_damaging	1	neutral	0,23	neutral	2,66	neutral	-2,9	deleterious	-7,38	high_impact	4,01	neutral	0,66	damaging	0,09	deleterious	3,67	23,2	0,15	0,4	neutral	0,34	disease	0,61	disease	0,6	disease	0,64	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,72	low_impact	-3,57	medium_impact	-0,02	high_impact	2,31	0,52	0,8	60,69	10,4	N	0,46	N	0,91	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3844	3844	C	G	MI.11867	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	538	180	P	A	Ccc/Gcc	0,68	0,99	0	probably_damaging	1	neutral	0,34	neutral	2,68	neutral	-2,51	deleterious	-7,38	high_impact	3,66	neutral	0,71	damaging	0,13	deleterious	3,04	22,4	0,16	0,45	neutral	0,3	disease	0,52	disease	0,67	disease	0,64	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,7	low_impact	-3,57	medium_impact	0,11	high_impact	2,01	0,64	0,8	60,69	10,4	N	0,46	N	0,78	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3845	3845	C	A	MI.11868	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	539	180	P	H	cCc/cAc	5,5	1	0	probably_damaging	1	neutral	0,26	neutral	2,61	deleterious	-5,05	deleterious	-8,31	high_impact	4,16	neutral	0,7	damaging	0,1	deleterious	4,16	23,8	0,08	0,35	disease	0,62	disease	0,74	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	0,02	high_impact	2,44	0,35	0,8	60,69	10,4	P	0,67	P	0,69	polymorphism	0,99	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3845	3845	C	G	MI.11869	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	539	180	P	R	cCc/cGc	5,5	1	0	probably_damaging	1	neutral	0,16	neutral	2,62	deleterious	-4,35	deleterious	-8,31	high_impact	4,7	neutral	0,76	damaging	0,1	deleterious	3,6	23,2	0,05	0,35	disease	0,52	disease	0,79	disease	0,78	disease	0,68	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	-0,13	high_impact	2,92	0,43	0,8	60,69	10,4	P	0,72	P	0,71	polymorphism	0,99	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9083	9083	T	G	MI.1187	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	557	186	L	R	cTt/cGt	-1,49	0	0	possibly_damaging	0,8	neutral	0,34	neutral	4,24	deleterious	-3,67	neutral	-1,55	medium_impact	2	neutral	0,82	neutral	0,49	deleterious	3,01	22,3	0,21	0,65	disease	0,64	disease	0,81	disease	0,57	disease	0,77	5	neutral	0,82	neutral	0,27	NA	0	deleterious	0,77	low_impact	-1,33	medium_impact	0,13	medium_impact	0,62	0,61	0,9	28,32	18,04	N	0,25	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3845	3845	C	T	MI.11870	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	539	180	P	L	cCc/cTc	5,5	1	0	probably_damaging	1	neutral	1	neutral	2,75	neutral	-1,73	deleterious	-9,24	medium_impact	2,52	neutral	0,78	damaging	0,1	deleterious	4,36	24,1	0,14	0,4	neutral	0,18	disease	0,75	disease	0,62	disease	0,64	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,7	low_impact	-3,57	high_impact	1,96	medium_impact	1,01	0,51	0,8	60,69	10,4	N	0,4	N	1	polymorphism	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3847	3847	T	G	MI.11871	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	541	181	L	V	Ttg/Gtg	-20	0	0,04	possibly_damaging	0,86	neutral	0,42	neutral	2,71	neutral	-1,11	deleterious	-2,6	medium_impact	2,52	neutral	0,75	damaging	0,17	deleterious	3,44	23	0,34	0,5	neutral	0,21	neutral	0,3	neutral	0,46	neutral	0,42	2	neutral	0,85	neutral	0,28	NA	0	deleterious	0,58	low_impact	-1,49	medium_impact	0,2	medium_impact	1,01	0,57	0,8	25,79	14,55	N	0,34	N	0,41	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3847	3847	T	A	MI.11872	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	541	181	L	M	Ttg/Atg	-20	0	0,04	possibly_damaging	0,68	neutral	0,29	neutral	2,62	neutral	-2,33	neutral	-1,4	medium_impact	2,37	neutral	0,84	neutral	0,77	deleterious	2,45	19,14	0,29	0,45	neutral	0,29	neutral	0,16	neutral	0,32	neutral	0,24	5	neutral	0,77	neutral	0,31	NA	0	neutral	0,43	low_impact	-1,06	medium_impact	0,06	medium_impact	0,88	0,46	0,8	25,79	14,55	N	0,43	N	0,11	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3848	3848	T	C	MI.11873	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	542	181	L	S	tTg/tCg	-0,93	0	0	probably_damaging	0,98	neutral	0,23	neutral	2,58	neutral	-2,35	deleterious	-5,29	medium_impact	3,46	neutral	0,76	damaging	0,14	deleterious	3,77	23,4	0,06	0,35	neutral	0,34	neutral	0,48	disease	0,58	disease	0,54	1	deleterious	0,98	neutral	0,13	deleterious	1	deleterious	0,68	low_impact	-2,34	medium_impact	-0,02	medium_impact	1,83	0,32	0,8	25,79	14,55	N	0,37	N	0,86	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3848	3848	T	G	MI.11874	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	542	181	L	W	tTg/tGg	-0,93	0	0	probably_damaging	0,99	neutral	0,22	neutral	2,52	deleterious	-5,57	deleterious	-5,29	high_impact	4,61	neutral	0,74	damaging	0,13	deleterious	3,78	23,4	0,06	0,35	disease	0,73	disease	0,58	disease	0,62	disease	0,62	2	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,74	low_impact	-2,62	medium_impact	-0,03	high_impact	2,84	0,28	0,8	25,79	14,55	N	0,46	N	0,9	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3849	3849	G	C	MI.11875	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	543	181	L	F	ttG/ttC	5,5	0,86	0,02	probably_damaging	0,96	neutral	0,82	neutral	2,57	neutral	-2,59	deleterious	-3,52	medium_impact	2,96	neutral	0,72	damaging	0,13	deleterious	3,45	23	0,2	0,45	neutral	0,42	neutral	0,43	disease	0,58	neutral	0,48	0	neutral	0,95	neutral	0,43	deleterious	1	deleterious	0,68	low_impact	-2,05	medium_impact	0,64	medium_impact	1,4	0,49	0,8	25,79	14,55	N	0,4	N	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3849	3849	G	T	MI.11876	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	543	181	L	F	ttG/ttT	5,5	0,86	0,02	probably_damaging	0,96	neutral	0,82	neutral	2,57	neutral	-2,59	deleterious	-3,52	medium_impact	2,96	neutral	0,72	damaging	0,13	deleterious	3,64	23,2	0,2	0,45	neutral	0,42	neutral	0,43	disease	0,58	neutral	0,48	0	neutral	0,95	neutral	0,43	deleterious	1	deleterious	0,68	low_impact	-2,05	medium_impact	0,64	medium_impact	1,4	0,49	0,8	25,79	14,55	N	0,41	N	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3850	3850	G	A	MI.11877	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	544	182	A	T	Gcc/Acc	-1,62	0	0	benign	0,02	neutral	0,41	neutral	2,73	neutral	-2,72	neutral	-2,21	low_impact	1,38	neutral	0,81	neutral	0,86	neutral	1,21	11,82	0,15	0,4	neutral	0,33	neutral	0,39	neutral	0,31	neutral	0,45	1	neutral	0,57	deleterious	0,7	neutral	-6	neutral	0,14	medium_impact	0,84	medium_impact	0,19	medium_impact	0,02	0,62	0,8	24,84	10,67	N	0,4	N	0,65	polymorphism	1	0,04	rs879213047	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3850	3850	G	C	MI.11878	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	544	182	A	P	Gcc/Ccc	-1,62	0	0	possibly_damaging	0,85	neutral	0,48	neutral	2,66	deleterious	-4,7	deleterious	-3,65	medium_impact	3,31	neutral	0,65	neutral	0,38	deleterious	2,14	17,11	0,04	0,35	disease	0,6	disease	0,77	disease	0,58	disease	0,62	2	neutral	0,84	neutral	0,32	NA	0	deleterious	0,68	low_impact	-1,46	medium_impact	0,26	medium_impact	1,7	0,36	0,8	24,84	10,67	N	0,38	N	0,98	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3850	3850	G	T	MI.11879	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	544	182	A	S	Gcc/Tcc	-1,62	0	0	benign	0,35	neutral	0,44	neutral	2,71	neutral	-2,58	neutral	-1,94	low_impact	1,26	neutral	0,82	neutral	0,6	neutral	1,8	14,99	0,22	0,45	neutral	0,28	neutral	0,35	neutral	0,27	neutral	0,43	1	neutral	0,48	deleterious	0,55	neutral	-6	neutral	0,28	medium_impact	-0,5	medium_impact	0,22	medium_impact	-0,09	0,38	0,8	24,84	10,67	N	0,39	N	0,45	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9085	9085	C	A	MI.1188	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	559	187	P	T	Ccc/Acc	-20	0	0	benign	0,38	neutral	0,67	neutral	4,48	neutral	2,41	neutral	0,39	neutral_impact	-0,8	neutral	0,85	neutral	0,97	neutral	-0,63	0,11	0,36	0,65	neutral	0,28	neutral	0,08	neutral	0,22	neutral	0,27	5	neutral	0,31	deleterious	0,65	neutral	-6	neutral	0,37	medium_impact	-0,55	medium_impact	0,47	low_impact	-1,78	0,82	0,9	26,11	13,5	N	0,38	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3851	3851	C	G	MI.11880	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	545	182	A	G	gCc/gGc	0,91	0	0	benign	0	neutral	0,36	neutral	2,68	neutral	-1,39	deleterious	-3,21	medium_impact	2,06	neutral	0,76	neutral	0,59	deleterious	2	16,2	0,17	0,45	disease	0,51	neutral	0,41	neutral	0,39	neutral	0,32	4	neutral	0,64	deleterious	0,68	neutral	-3	neutral	0,17	high_impact	2,07	medium_impact	0,14	medium_impact	0,61	0,5	0,8	24,84	10,67	N	0,43	N	0,7	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3851	3851	C	T	MI.11881	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	545	182	A	V	gCc/gTc	0,91	0	0	benign	0,35	neutral	0,51	neutral	2,81	neutral	-1,71	neutral	-2,45	medium_impact	2,42	neutral	0,82	neutral	0,52	deleterious	2,61	20,2	0,15	0,4	neutral	0,18	disease	0,56	neutral	0,43	neutral	0,43	1	neutral	0,41	deleterious	0,58	neutral	-3	neutral	0,28	medium_impact	-0,5	medium_impact	0,29	medium_impact	0,93	0,62	0,8	24,84	10,67	N	0,29	N	0,68	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3851	3851	C	A	MI.11882	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	545	182	A	D	gCc/gAc	0,91	0	0	possibly_damaging	0,68	neutral	0,19	neutral	2,66	deleterious	-4,91	deleterious	-4,47	high_impact	3,87	neutral	0,72	neutral	0,38	deleterious	2,63	20,4	0,03	0,35	disease	0,63	disease	0,77	disease	0,64	disease	0,65	3	neutral	0,84	neutral	0,26	deleterious	1	deleterious	0,57	low_impact	-1,06	medium_impact	-0,08	high_impact	2,19	0,31	0,8	24,84	10,67	N	0,45	N	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3853	3853	A	C	MI.11883	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	547	183	M	L	Ata/Cta	-8,97	0	0	benign	0,01	neutral	0,88	neutral	3	neutral	2,1	neutral	-1,47	neutral_impact	0,28	neutral	0,84	damaging	0,27	deleterious	0,38	6,44	0,21	0,45	neutral	0,14	neutral	0,48	neutral	0,36	neutral	0,32	4	neutral	0,09	deleterious	0,94	neutral	-6	neutral	0,13	medium_impact	1,12	medium_impact	0,76	medium_impact	-0,94	0,31	0,8	52,52	8,77	N	0,23	N	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3853	3853	A	G	MI.11884	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	547	183	M	V	Ata/Gta	-8,97	0	0	benign	0,25	neutral	0,58	neutral	2,91	neutral	1,79	neutral	-1,62	low_impact	1,54	neutral	0,7	damaging	0,11	deleterious	0,89	10	0,21	0,45	neutral	0,12	disease	0,55	neutral	0,44	neutral	0,18	6	neutral	0,31	deleterious	0,67	neutral	-6	neutral	0,25	medium_impact	-0,3	medium_impact	0,35	medium_impact	0,16	0,31	0,8	52,52	8,77	N	0,24	N	0,86	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3853	3853	A	T	MI.11885	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	547	183	M	L	Ata/Tta	-8,97	0	0	benign	0,01	neutral	0,88	neutral	3	neutral	2,1	neutral	-1,47	neutral_impact	0,28	neutral	0,84	damaging	0,27	deleterious	0,53	7,67	0,21	0,45	neutral	0,14	neutral	0,48	neutral	0,36	neutral	0,32	4	neutral	0,09	deleterious	0,94	neutral	-6	neutral	0,13	medium_impact	1,12	medium_impact	0,76	medium_impact	-0,94	0,31	0,8	52,52	8,77	N	0,24	N	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3854	3854	T	A	MI.11886	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	548	183	M	K	aTa/aAa	3,44	0,99	0	benign	0,36	neutral	0,32	neutral	2,76	neutral	-1,63	deleterious	-3,17	high_impact	3,83	neutral	0,64	damaging	0,07	deleterious	2,11	16,89	0,04	0,35	neutral	0,39	disease	0,79	disease	0,67	disease	0,7	4	neutral	0,62	deleterious	0,48	neutral	-2	deleterious	0,47	medium_impact	-0,52	medium_impact	0,09	high_impact	2,16	0,25	0,8	52,52	8,77	N	0,51	P	0,95	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3854	3854	T	C	MI.11887	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	548	183	M	T	aTa/aCa	3,44	0,99	0	benign	0,02	neutral	0,41	neutral	2,79	neutral	-0,2	neutral	-2,3	medium_impact	2,59	neutral	0,8	neutral	0,3	neutral	-0,07	1,95	0,1	0,4	neutral	0,23	disease	0,56	neutral	0,46	neutral	0,17	7	neutral	0,57	deleterious	0,7	neutral	-3	neutral	0,16	medium_impact	0,84	medium_impact	0,19	medium_impact	1,07	0,22	0,8	52,52	8,77	N	0,47	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3855	3855	A	C	MI.11888	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	549	183	M	I	atA/atC	4,13	1	0	benign	0,17	neutral	0,43	neutral	2,92	neutral	1,72	neutral	-1,95	low_impact	1,38	neutral	0,73	damaging	0,19	neutral	1,5	13,29	0,21	0,45	neutral	0,15	disease	0,61	neutral	0,4	neutral	0,19	6	neutral	0,49	deleterious	0,63	neutral	-6	neutral	0,25	medium_impact	-0,1	medium_impact	0,21	medium_impact	0,02	0,33	0,8	52,52	8,77	N	0,51	P	0,81	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3855	3855	A	T	MI.11889	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	549	183	M	I	atA/atT	4,13	1	0	benign	0,17	neutral	0,43	neutral	2,92	neutral	1,72	neutral	-1,95	low_impact	1,38	neutral	0,73	damaging	0,19	neutral	1,55	13,59	0,21	0,45	neutral	0,15	disease	0,61	neutral	0,4	neutral	0,19	6	neutral	0,49	deleterious	0,63	neutral	-6	neutral	0,25	medium_impact	-0,1	medium_impact	0,21	medium_impact	0,02	0,33	0,8	52,52	8,77	N	0,52	P	0,81	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9085	9085	C	G	MI.1189	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	559	187	P	A	Ccc/Gcc	-20	0	0	benign	0,18	neutral	0,61	neutral	4,47	neutral	2,22	neutral	-0,64	neutral_impact	-0,54	neutral	0,85	neutral	0,94	neutral	-0,47	0,27	0,34	0,65	neutral	0,31	neutral	0,09	neutral	0,3	neutral	0,26	5	neutral	0,27	deleterious	0,72	neutral	-6	neutral	0,28	medium_impact	-0,13	medium_impact	0,4	low_impact	-1,56	0,83	0,9	26,11	13,5	N	0,41	N	0,63	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3856	3856	A	C	MI.11890	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	550	184	M	L	Ata/Cta	-0,01	0,96	0	probably_damaging	0,98	neutral	1	neutral	2,86	neutral	2,08	deleterious	-2,78	low_impact	1,66	damaging	0,57	damaging	0,08	deleterious	3,19	22,7	0,21	0,45	neutral	0,11	disease	0,69	disease	0,55	neutral	0,22	6	deleterious	0,98	deleterious	0,51	neutral	-2	deleterious	0,7	low_impact	-2,34	high_impact	1,96	medium_impact	0,26	0,39	0,8	59,43	10,31	N	0,32	N	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3856	3856	A	G	MI.11891	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	550	184	M	V	Ata/Gta	-0,01	0,96	0	probably_damaging	0,99	neutral	0,55	neutral	2,89	neutral	2,1	deleterious	-3,72	medium_impact	1,96	neutral	0,7	damaging	0,13	deleterious	2,65	20,5	0,25	0,45	neutral	0,13	disease	0,59	neutral	0,46	neutral	0,15	7	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,69	low_impact	-2,62	medium_impact	0,32	medium_impact	0,52	0,4	0,8	59,43	10,31	N	0,32	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3856	3856	A	T	MI.11892	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	550	184	M	L	Ata/Tta	-0,01	0,96	0	probably_damaging	0,98	neutral	1	neutral	2,86	neutral	2,08	deleterious	-2,78	low_impact	1,66	damaging	0,57	damaging	0,08	deleterious	3,26	22,8	0,21	0,45	neutral	0,11	disease	0,69	disease	0,55	neutral	0,22	6	deleterious	0,98	deleterious	0,51	neutral	-2	deleterious	0,7	low_impact	-2,34	high_impact	1,96	medium_impact	0,26	0,39	0,8	59,43	10,31	N	0,33	N	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3857	3857	T	A	MI.11893	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	551	184	M	K	aTa/aAa	8,49	1	0	probably_damaging	1	neutral	0,28	neutral	2,73	neutral	-1,54	deleterious	-5,58	high_impact	3,75	neutral	0,63	damaging	0,08	deleterious	4,15	23,8	0,03	0,35	neutral	0,44	disease	0,82	disease	0,71	disease	0,68	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,05	high_impact	2,09	0,26	0,8	59,43	10,31	P	0,65	P	1	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3857	3857	T	C	MI.11894	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	551	184	M	T	aTa/aCa	8,49	1	0	probably_damaging	1	neutral	0,43	neutral	2,78	neutral	0,05	deleterious	-5,58	medium_impact	3,02	neutral	0,72	damaging	0,18	deleterious	3,06	22,4	0,13	0,4	neutral	0,27	disease	0,73	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	0,21	medium_impact	1,45	0,15	0,8	59,43	10,31	N	0,54	P	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3858	3858	A	C	MI.11895	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	552	184	M	I	atA/atC	5,5	1	0	probably_damaging	0,99	neutral	0,55	neutral	2,88	neutral	2,22	deleterious	-3,71	low_impact	1,8	neutral	0,63	damaging	0,09	deleterious	3,43	23	0,22	0,45	neutral	0,11	disease	0,72	neutral	0,45	neutral	0,15	7	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,72	low_impact	-2,62	medium_impact	0,32	medium_impact	0,38	0,4	0,8	59,43	10,31	N	0,45	N	0,95	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3858	3858	A	T	MI.11896	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	552	184	M	I	atA/atT	5,5	1	0	probably_damaging	0,99	neutral	0,55	neutral	2,88	neutral	2,22	deleterious	-3,71	low_impact	1,8	neutral	0,63	damaging	0,09	deleterious	3,45	23	0,22	0,45	neutral	0,11	disease	0,72	neutral	0,45	neutral	0,15	7	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,72	low_impact	-2,62	medium_impact	0,32	medium_impact	0,38	0,4	0,8	59,43	10,31	N	0,45	N	0,95	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3859	3859	T	C	MI.11897	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	553	185	W	R	Tga/Cga	2,06	1	0	probably_damaging	1	neutral	0,34	neutral	2,58	deleterious	-3,9	deleterious	-13,02	high_impact	4,17	damaging	0,56	damaging	0,08	deleterious	3,59	23,2	0,05	0,35	neutral	0,42	disease	0,89	disease	0,78	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,11	high_impact	2,45	0,12	0,8	59,12	10,43	P	0,57	P	0,98	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3859	3859	T	G	MI.11898	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	553	185	W	G	Tga/Gga	2,06	1	0	probably_damaging	1	neutral	0,34	neutral	2,58	deleterious	-4,13	deleterious	-12,09	high_impact	3,97	damaging	0,53	damaging	0,08	deleterious	3,87	23,5	0,06	0,35	neutral	0,43	disease	0,8	disease	0,73	disease	0,67	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	0,11	high_impact	2,28	0,15	0,8	59,12	10,43	N	0,48	N	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3860	3860	G	T	MI.11899	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	554	185	W	L	tGa/tTa	7,34	1	0	probably_damaging	1	neutral	0,8	neutral	2,66	neutral	-1,36	deleterious	-12,09	medium_impact	2,15	damaging	0,56	damaging	0,05	deleterious	4,27	23,9	0,09	0,35	neutral	0,14	disease	0,78	disease	0,68	neutral	0,35	3	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,61	medium_impact	0,69	0,1	0,8	59,12	10,43	N	0,41	N	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8581	8581	G	C	MI.119	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	55	19	A	P	Gcc/Ccc	-4,73	0	0	probably_damaging	1	deleterious	0	neutral	4,58	neutral	-2,69	neutral	-2,4	neutral_impact	0,46	neutral	0,68	neutral	0,39	deleterious	3,66	23,2	0,13	0,65	disease	0,8	disease	0,82	disease	0,61	disease	0,8	6	deleterious	1	neutral	0	deleterious	2	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	medium_impact	-0,7	0,64	0,9	29,65	29,28	N	0,24	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9085	9085	C	T	MI.1190	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	559	187	P	S	Ccc/Tcc	-20	0	0	benign	0,03	neutral	0,51	neutral	4,48	neutral	2,45	neutral	-0,41	neutral_impact	0,12	neutral	0,94	neutral	0,96	deleterious	0,33	6	0,49	0,65	neutral	0,45	neutral	0,2	neutral	0,26	neutral	0,37	3	neutral	0,45	deleterious	0,74	neutral	-6	neutral	0,15	medium_impact	0,68	medium_impact	0,3	medium_impact	-1	0,34	0,9	26,11	13,5	N	0,43	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3860	3860	G	C	MI.11900	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	554	185	W	S	tGa/tCa	7,34	1	0	probably_damaging	1	neutral	0,48	neutral	2,59	deleterious	-3,25	deleterious	-13,02	high_impact	3,83	damaging	0,45	damaging	0,09	deleterious	4,04	23,7	0,07	0,35	neutral	0,29	disease	0,86	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,26	high_impact	2,16	0,11	0,8	59,12	10,43	P	0,54	P	0,99	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3861	3861	A	T	MI.11901	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	555	185	W	C	tgA/tgT	8,95	1	0	probably_damaging	1	neutral	0,21	neutral	2,57	deleterious	-4,77	deleterious	-12,09	high_impact	3,97	damaging	0,54	damaging	0,04	deleterious	4,12	23,8	0,06	0,35	neutral	0,24	disease	0,87	disease	0,75	disease	0,68	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,73	low_impact	-3,57	medium_impact	-0,05	high_impact	2,28	0,15	0,8	59,12	10,43	P	0,55	P	1	polymorphism	1	0,16	.	.	.	.	.	.	COSM1138358	.	.	.	.	.	.	.	.
chrM	3861	3861	A	C	MI.11902	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	555	185	W	C	tgA/tgC	8,95	1	0	probably_damaging	1	neutral	0,21	neutral	2,57	deleterious	-4,77	deleterious	-12,09	high_impact	3,97	damaging	0,54	damaging	0,04	deleterious	4,07	23,7	0,06	0,35	neutral	0,24	disease	0,87	disease	0,75	disease	0,68	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,73	low_impact	-3,57	medium_impact	-0,05	high_impact	2,28	0,15	0,8	59,12	10,43	P	0,54	P	1	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3862	3862	T	C	MI.11903	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	556	186	F	L	Ttt/Ctt	1,6	1	0	benign	0,05	neutral	0,77	neutral	2,82	neutral	-0,84	deleterious	-4,49	low_impact	1,7	neutral	0,76	damaging	0,14	deleterious	4,15	23,8	0,19	0,45	neutral	0,13	disease	0,64	neutral	0,37	neutral	0,17	7	neutral	0,15	deleterious	0,86	neutral	-6	neutral	0,15	medium_impact	0,45	medium_impact	0,57	medium_impact	0,3	0,59	0,8	20,44	21,33	N	0,41	N	0,8	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3862	3862	T	G	MI.11904	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	556	186	F	V	Ttt/Gtt	1,6	1	0	possibly_damaging	0,64	neutral	0,54	neutral	2,71	neutral	-1,65	deleterious	-4,9	medium_impact	2,46	neutral	0,82	damaging	0,14	deleterious	4,12	23,8	0,1	0,4	neutral	0,19	disease	0,77	neutral	0,43	neutral	0,18	6	neutral	0,61	neutral	0,45	NA	0	deleterious	0,5	medium_impact	-0,99	medium_impact	0,31	medium_impact	0,96	0,32	0,8	20,44	21,33	N	0,38	N	0,86	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3862	3862	T	A	MI.11905	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	556	186	F	I	Ttt/Att	1,6	1	0	possibly_damaging	0,52	neutral	0,47	neutral	2,68	neutral	-1,81	deleterious	-4,5	medium_impact	2,41	neutral	0,72	damaging	0,11	deleterious	4,47	24,2	0,14	0,4	neutral	0,2	disease	0,8	disease	0,53	neutral	0,45	1	neutral	0,53	deleterious	0,48	NA	0	deleterious	0,5	medium_impact	-0,78	medium_impact	0,25	medium_impact	0,92	0,46	0,8	20,44	21,33	N	0,46	N	0,83	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3863	3863	T	A	MI.11906	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	557	186	F	Y	tTt/tAt	7,34	1	0	benign	0,08	neutral	1	neutral	2,69	deleterious	-3	neutral	0,93	low_impact	1,3	neutral	0,83	neutral	0,91	neutral	1,66	14,19	0,15	0,4	neutral	0,32	neutral	0,18	neutral	0,34	neutral	0,25	5	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,16	medium_impact	0,25	high_impact	1,96	medium_impact	-0,05	0,59	0,8	20,44	21,33	P	0,54	P	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3863	3863	T	C	MI.11907	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	557	186	F	S	tTt/tCt	7,34	1	0	probably_damaging	0,91	neutral	0,45	neutral	2,63	deleterious	-3,43	deleterious	-5,83	medium_impact	3,44	neutral	0,7	damaging	0,11	deleterious	4,35	24,1	0,05	0,35	neutral	0,36	disease	0,79	disease	0,59	disease	0,66	3	neutral	0,9	neutral	0,27	deleterious	1	deleterious	0,69	low_impact	-1,69	medium_impact	0,23	medium_impact	1,82	0,39	0,8	20,44	21,33	P	0,54	P	0,98	polymorphism	1	0,2	.	.	.	.	.	.	COSM1138360	.	.	.	.	.	.	.	.
chrM	3863	3863	T	G	MI.11908	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	557	186	F	C	tTt/tGt	7,34	1	0	probably_damaging	0,98	neutral	0,2	neutral	2,59	deleterious	-4,4	deleterious	-5,83	high_impact	3,99	neutral	0,71	damaging	0,1	deleterious	4,13	23,8	0,04	0,35	disease	0,55	disease	0,84	disease	0,62	disease	0,68	4	deleterious	0,98	neutral	0,11	deleterious	2	deleterious	0,74	low_impact	-2,34	medium_impact	-0,06	high_impact	2,3	0,2	0,8	20,44	21,33	P	0,59	P	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3864	3864	T	A	MI.11909	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	558	186	F	L	ttT/ttA	1,83	0,95	0	benign	0,05	neutral	0,77	neutral	2,82	neutral	-0,84	deleterious	-4,49	low_impact	1,7	neutral	0,76	damaging	0,14	deleterious	4,45	24,2	0,19	0,45	neutral	0,13	disease	0,64	neutral	0,37	neutral	0,17	7	neutral	0,15	deleterious	0,86	neutral	-6	neutral	0,15	medium_impact	0,45	medium_impact	0,57	medium_impact	0,3	0,59	0,8	20,44	21,33	N	0,34	N	0,8	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9086	9086	C	T	MI.1191	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	560	187	P	L	cCc/cTc	-4,73	0	0	possibly_damaging	0,6	neutral	0,74	neutral	4,55	neutral	3,21	neutral	-0,78	neutral_impact	-1,24	neutral	0,86	neutral	0,93	deleterious	2,61	20,2	0,4	0,65	neutral	0,22	neutral	0,36	neutral	0,29	neutral	0,45	1	neutral	0,52	deleterious	0,57	neutral	-3	deleterious	0,46	medium_impact	-0,92	medium_impact	0,55	low_impact	-2,16	0,85	0,9	26,11	13,5	N	0,27	N	0,79	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3864	3864	T	G	MI.11910	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	558	186	F	L	ttT/ttG	1,83	0,95	0	benign	0,05	neutral	0,77	neutral	2,82	neutral	-0,84	deleterious	-4,49	low_impact	1,7	neutral	0,76	damaging	0,14	deleterious	4,34	24	0,19	0,45	neutral	0,13	disease	0,64	neutral	0,37	neutral	0,17	7	neutral	0,15	deleterious	0,86	neutral	-6	neutral	0,15	medium_impact	0,45	medium_impact	0,57	medium_impact	0,3	0,59	0,8	20,44	21,33	N	0,34	N	0,8	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3865	3865	A	C	MI.11911	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	559	187	I	L	Atc/Ctc	-2,77	0	0	benign	0,17	neutral	1	neutral	2,55	neutral	-1,61	neutral	-1,68	medium_impact	2,73	neutral	0,72	neutral	0,39	deleterious	1,92	15,72	0,21	0,45	neutral	0,33	disease	0,54	disease	0,53	disease	0,58	2	neutral	0,17	deleterious	0,92	neutral	-3	neutral	0,22	medium_impact	-0,1	high_impact	1,96	medium_impact	1,2	0,41	0,8	23,9	24,14	N	0,27	N	0,67	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3865	3865	A	G	MI.11912	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	559	187	I	V	Atc/Gtc	-2,77	0	0	benign	0,01	neutral	0,33	neutral	2,64	neutral	-1,18	neutral	-0,38	neutral_impact	0,58	neutral	0,84	neutral	0,84	neutral	-0,16	1,33	0,4	0,5	neutral	0,2	neutral	0,11	neutral	0,31	neutral	0,26	5	neutral	0,66	deleterious	0,66	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	0,1	medium_impact	-0,68	0,31	0,8	23,9	24,14	N	0,43	N	0,12	polymorphism	1	0,02	rs878989562	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3865	3865	A	T	MI.11913	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	559	187	I	F	Atc/Ttc	-2,77	0	0	possibly_damaging	0,83	neutral	0,54	neutral	2,47	neutral	-2,97	deleterious	-3,45	medium_impact	2,52	neutral	0,69	neutral	0,37	deleterious	3,43	23	0,13	0,4	neutral	0,33	disease	0,67	disease	0,58	disease	0,65	3	neutral	0,81	neutral	0,36	NA	0	deleterious	0,61	low_impact	-1,4	medium_impact	0,31	medium_impact	1,01	0,41	0,8	23,9	24,14	N	0,32	N	0,77	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3866	3866	T	A	MI.11914	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	560	187	I	N	aTc/aAc	2,06	0,83	0,01	possibly_damaging	0,78	neutral	0,19	neutral	2,43	deleterious	-5,22	deleterious	-5,62	high_impact	3,88	neutral	0,72	neutral	0,4	deleterious	4,3	24	0,08	0,35	disease	0,76	disease	0,78	disease	0,6	disease	0,67	3	neutral	0,88	neutral	0,21	deleterious	1	deleterious	0,67	low_impact	-1,27	medium_impact	-0,08	high_impact	2,2	0,26	0,8	23,9	24,14	N	0,48	N	0,95	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3866	3866	T	G	MI.11915	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	560	187	I	S	aTc/aGc	2,06	0,83	0,01	possibly_damaging	0,48	neutral	0,32	neutral	2,47	deleterious	-3,87	deleterious	-4,68	medium_impact	1,99	neutral	0,69	neutral	0,44	deleterious	2,69	20,7	0,03	0,35	neutral	0,49	disease	0,6	neutral	0,42	neutral	0,21	6	neutral	0,65	neutral	0,42	NA	0	neutral	0,42	medium_impact	-0,72	medium_impact	0,09	medium_impact	0,55	0,15	0,8	23,9	24,14	N	0,45	N	0,83	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3866	3866	T	C	MI.11916	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	560	187	I	T	aTc/aCc	2,06	0,83	0,01	benign	0,03	neutral	0,27	neutral	2,47	deleterious	-3,15	deleterious	-3,33	low_impact	1,49	neutral	0,81	neutral	0,83	deleterious	0,44	6,95	0,07	0,35	disease	0,53	neutral	0,42	neutral	0,39	neutral	0,35	3	neutral	0,72	deleterious	0,62	neutral	-6	neutral	0,18	medium_impact	0,67	medium_impact	0,03	medium_impact	0,11	0,21	0,8	23,9	24,14	N	0,51	P	0,39	polymorphism	1	0,12	rs200479541	.	.	.	.	.	.	CPD	9,94	T3866C	LHON+ limb claudication	.	.	Reported	2
chrM	3867	3867	C	A	MI.11917	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	561	187	I	M	atC/atA	3,67	0,89	0	possibly_damaging	0,87	neutral	0,38	neutral	2,45	deleterious	-3,51	neutral	-2,33	medium_impact	2,66	neutral	0,7	neutral	0,45	deleterious	3,53	23,1	0,21	0,45	disease	0,57	neutral	0,47	neutral	0,5	disease	0,58	2	neutral	0,87	neutral	0,26	NA	0	deleterious	0,62	low_impact	-1,53	medium_impact	0,16	medium_impact	1,14	0,37	0,8	23,9	24,14	N	0,46	N	0,72	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3867	3867	C	G	MI.11918	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	561	187	I	M	atC/atG	3,67	0,89	0	possibly_damaging	0,87	neutral	0,38	neutral	2,45	deleterious	-3,51	neutral	-2,33	medium_impact	2,66	neutral	0,7	neutral	0,45	deleterious	3,13	22,6	0,21	0,45	disease	0,57	neutral	0,47	neutral	0,5	disease	0,58	2	neutral	0,87	neutral	0,26	NA	0	deleterious	0,62	low_impact	-1,53	medium_impact	0,16	medium_impact	1,14	0,37	0,8	23,9	24,14	N	0,46	N	0,72	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3868	3868	T	A	MI.11919	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	562	188	S	T	Tcc/Acc	-3	0	0	probably_damaging	1	neutral	0,39	neutral	2,61	neutral	-1,3	deleterious	-2,77	medium_impact	2,71	damaging	0,59	damaging	0,05	deleterious	3,76	23,4	0,22	0,45	neutral	0,27	disease	0,54	disease	0,56	neutral	0,23	5	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,17	medium_impact	1,18	0,59	0,8	59,12	10,46	N	0,27	N	0,68	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9086	9086	C	G	MI.1192	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	560	187	P	R	cCc/cGc	-4,73	0	0	possibly_damaging	0,77	neutral	0,31	neutral	4,43	neutral	1,54	neutral	-1,77	low_impact	1,66	neutral	0,89	neutral	0,44	deleterious	2,26	17,9	0,31	0,65	disease	0,62	disease	0,56	disease	0,65	disease	0,7	4	neutral	0,81	neutral	0,27	neutral	-3	deleterious	0,63	low_impact	-1,25	medium_impact	0,1	medium_impact	0,33	0,72	0,9	26,11	13,5	N	0,34	N	0,92	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3868	3868	T	G	MI.11920	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	562	188	S	A	Tcc/Gcc	-3	0	0	probably_damaging	1	neutral	0,54	neutral	2,72	neutral	0,73	deleterious	-2,77	medium_impact	2,45	neutral	0,6	damaging	0,11	deleterious	3,65	23,2	0,3	0,45	neutral	0,16	disease	0,51	disease	0,62	disease	0,62	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,69	low_impact	-3,57	medium_impact	0,31	medium_impact	0,95	0,55	0,8	59,12	10,46	N	0,23	N	0,46	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3868	3868	T	C	MI.11921	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	562	188	S	P	Tcc/Ccc	-3	0	0	probably_damaging	1	neutral	0,22	neutral	2,56	deleterious	-3,85	deleterious	-4,63	high_impact	3,88	neutral	0,65	damaging	0,04	deleterious	3,96	23,6	0,04	0,35	disease	0,5	disease	0,75	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	-0,03	high_impact	2,2	0,26	0,8	59,12	10,46	N	0,36	N	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3869	3869	C	T	MI.11922	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	563	188	S	F	tCc/tTc	7,34	1	0	probably_damaging	1	neutral	0,72	neutral	2,57	neutral	-2,21	deleterious	-5,53	high_impact	4,33	neutral	0,61	damaging	0,02	deleterious	4,29	24	0,04	0,35	neutral	0,47	disease	0,79	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,51	high_impact	2,59	0,15	0,8	59,12	10,46	P	0,53	P	1	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3869	3869	C	A	MI.11923	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	563	188	S	Y	tCc/tAc	7,34	1	0	probably_damaging	1	neutral	1	neutral	2,56	deleterious	-3,04	deleterious	-5,54	high_impact	4,68	neutral	0,61	damaging	0,04	deleterious	4,11	23,7	0,04	0,35	disease	0,52	disease	0,78	disease	0,66	disease	0,67	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,78	low_impact	-3,57	high_impact	1,96	high_impact	2,9	0,25	0,8	59,12	10,46	P	0,59	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3869	3869	C	G	MI.11924	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	563	188	S	C	tCc/tGc	7,34	1	0	probably_damaging	1	neutral	0,18	neutral	2,56	neutral	-2,39	deleterious	-4,6	medium_impact	2,72	neutral	0,67	damaging	0,07	deleterious	3,57	23,1	0,06	0,35	neutral	0,43	disease	0,69	disease	0,56	disease	0,5	0	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	-0,09	medium_impact	1,19	0,34	0,8	59,12	10,46	P	0,56	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3871	3871	A	C	MI.11925	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	565	189	T	P	Aca/Cca	-10,81	0	0	probably_damaging	1	neutral	0,21	neutral	2,67	neutral	-2,94	deleterious	-5,52	high_impact	3,94	neutral	0,62	damaging	0,07	deleterious	3,52	23,1	0,04	0,35	disease	0,54	disease	0,84	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	-0,05	high_impact	2,25	0,44	0,8	60,06	10,25	N	0,31	N	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3871	3871	A	T	MI.11926	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	565	189	T	S	Aca/Tca	-10,81	0	0	probably_damaging	1	neutral	0,41	neutral	2,79	neutral	0,38	deleterious	-3,68	low_impact	1,88	damaging	0,6	damaging	0,09	deleterious	3,4	23	0,32	0,5	neutral	0,19	disease	0,52	neutral	0,36	neutral	0,18	6	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,69	low_impact	-3,57	medium_impact	0,19	medium_impact	0,45	0,68	0,85	60,06	10,25	N	0,28	N	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3871	3871	A	G	MI.11927	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	565	189	T	A	Aca/Gca	-10,81	0	0	probably_damaging	1	neutral	0,53	neutral	2,82	neutral	0,86	deleterious	-4,61	low_impact	1,86	neutral	0,66	damaging	0,09	deleterious	3,48	23,1	0,25	0,45	neutral	0,18	disease	0,53	neutral	0,4	neutral	0,17	7	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,68	low_impact	-3,57	medium_impact	0,3	medium_impact	0,44	0,5	0,8	60,06	10,25	N	0,25	N	0,65	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3872	3872	C	A	MI.11928	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	566	189	T	K	aCa/aAa	8,49	1	0	probably_damaging	1	neutral	0,29	neutral	2,73	neutral	-2,29	deleterious	-5,54	medium_impact	3,13	neutral	0,64	damaging	0,05	deleterious	4,45	24,2	0,06	0,35	neutral	0,41	disease	0,85	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,78	low_impact	-3,57	medium_impact	0,06	medium_impact	1,55	0,39	0,8	60,06	10,25	P	0,55	P	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3872	3872	C	T	MI.11929	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	566	189	T	M	aCa/aTa	8,49	1	0	probably_damaging	1	neutral	0,24	neutral	2,69	neutral	0,14	deleterious	-5,54	low_impact	1,71	neutral	0,66	damaging	0,05	deleterious	4,07	23,7	0,21	0,45	neutral	0,21	disease	0,71	neutral	0,41	neutral	0,14	7	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,68	low_impact	-3,57	medium_impact	-0,01	medium_impact	0,31	0,75	0,85	60,06	10,25	N	0,47	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9086	9086	C	A	MI.1193	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	560	187	P	H	cCc/cAc	-4,73	0	0	possibly_damaging	0,9	neutral	0,48	neutral	4,39	neutral	0,08	neutral	-2,13	low_impact	1,32	neutral	0,85	neutral	0,43	deleterious	2,86	21,7	0,32	0,65	disease	0,53	neutral	0,39	disease	0,58	disease	0,52	0	neutral	0,9	neutral	0,29	neutral	-3	deleterious	0,66	low_impact	-1,66	medium_impact	0,27	medium_impact	0,03	0,67	0,9	26,11	13,5	N	0,25	N	0,86	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3874	3874	C	A	MI.11930	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	568	190	L	M	Cta/Ata	-4,38	0	0	probably_damaging	1	neutral	0,72	neutral	1,98	deleterious	-4,07	neutral	-1,86	medium_impact	2,84	neutral	0,76	damaging	0,12	deleterious	3,8	23,4	0,28	0,45	neutral	0,47	disease	0,55	disease	0,53	neutral	0,25	5	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	0,51	medium_impact	1,29	0,64	0,8	59,75	10,55	N	0,21	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3874	3874	C	G	MI.11931	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	568	190	L	V	Cta/Gta	-4,38	0	0	probably_damaging	1	neutral	0,59	neutral	2,1	neutral	-2,59	deleterious	-2,78	medium_impact	2,77	neutral	0,68	damaging	0,09	deleterious	3,46	23	0,25	0,45	neutral	0,33	disease	0,59	disease	0,55	neutral	0,49	0	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	0,36	medium_impact	1,23	0,47	0,8	59,75	10,55	N	0,2	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3875	3875	T	G	MI.11932	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	569	190	L	R	cTa/cGa	-0,24	0	0	probably_damaging	1	neutral	0,23	neutral	1,92	deleterious	-6,2	deleterious	-5,58	high_impact	4,76	neutral	0,75	damaging	0,07	deleterious	4,23	23,9	0,04	0,35	disease	0,74	disease	0,89	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	-0,02	high_impact	2,97	0,12	0,8	59,75	10,55	P	0,64	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3875	3875	T	A	MI.11933	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	569	190	L	Q	cTa/cAa	-0,24	0	0	probably_damaging	1	neutral	0,14	neutral	1,92	deleterious	-6,22	deleterious	-5,58	high_impact	4,42	neutral	0,73	damaging	0,09	deleterious	4,39	24,1	0,05	0,35	disease	0,75	disease	0,82	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	-0,17	high_impact	2,67	0,22	0,8	59,75	10,55	N	0,39	N	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3875	3875	T	C	MI.11934	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	569	190	L	P	cTa/cCa	-0,24	0	0	probably_damaging	1	neutral	0,15	neutral	1,92	deleterious	-6,85	deleterious	-6,51	high_impact	3,96	neutral	0,77	damaging	0,08	deleterious	3,98	23,6	0,04	0,35	disease	0,8	disease	0,81	disease	0,74	disease	0,68	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	-0,15	high_impact	2,27	0,19	0,8	59,75	10,55	N	0,33	N	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3877	3877	G	A	MI.11935	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	571	191	A	T	Gca/Aca	-0,01	0,95	0	probably_damaging	1	neutral	0,39	neutral	1,76	deleterious	-4,57	deleterious	-3,69	high_impact	4,54	neutral	0,61	damaging	0,03	deleterious	4,27	24	0,1	0,4	neutral	0,43	disease	0,8	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,17	high_impact	2,78	0,69	0,85	60,06	10,33	P	0,56	P	0,7	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3877	3877	G	T	MI.11936	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	571	191	A	S	Gca/Tca	-0,01	0,95	0	probably_damaging	1	neutral	0,41	neutral	1,78	deleterious	-4,1	deleterious	-2,78	medium_impact	3,44	neutral	0,6	damaging	0,04	deleterious	3,75	23,3	0,16	0,45	neutral	0,48	disease	0,8	disease	0,59	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,82	low_impact	-3,57	medium_impact	0,19	medium_impact	1,82	0,48	0,8	60,06	10,33	N	0,39	N	0,93	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3877	3877	G	C	MI.11937	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	571	191	A	P	Gca/Cca	-0,01	0,95	0	probably_damaging	1	neutral	0,21	neutral	1,72	deleterious	-5,95	deleterious	-4,63	high_impact	4,08	neutral	0,65	damaging	0,03	deleterious	3,87	23,5	0,03	0,35	disease	0,71	disease	0,85	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,05	high_impact	2,38	0,49	0,8	60,06	10,33	N	0,48	N	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3878	3878	C	T	MI.11938	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	572	191	A	V	gCa/gTa	8,95	1	0	probably_damaging	1	neutral	0,5	neutral	1,75	deleterious	-4,79	deleterious	-3,66	high_impact	3,68	neutral	0,7	damaging	0,03	deleterious	4,47	24,2	0,08	0,35	neutral	0,3	disease	0,81	disease	0,6	disease	0,66	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,28	high_impact	2,03	0,74	0,85	60,06	10,33	P	0,56	P	0,72	polymorphism	0,99	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3878	3878	C	A	MI.11939	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	572	191	A	E	gCa/gAa	8,95	1	0	probably_damaging	1	neutral	0,27	neutral	1,73	deleterious	-5,49	deleterious	-4,63	high_impact	4,34	neutral	0,69	damaging	0,03	deleterious	4,55	24,4	0,03	0,35	disease	0,58	disease	0,87	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,03	high_impact	2,6	0,2	0,8	60,06	10,33	P	0,65	P	0,96	polymorphism	0,99	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9088	9088	T	C	MI.1194	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	562	188	S	P	Tct/Cct	-4,04	0	0	benign	0,12	neutral	0,11	neutral	4,3	neutral	-2,54	neutral	-0,81	neutral_impact	0,78	neutral	0,9	neutral	0,56	deleterious	2,19	17,46	0,24	0,65	disease	0,63	disease	0,78	disease	0,64	disease	0,76	5	neutral	0,88	deleterious	0,5	neutral	-6	neutral	0,37	medium_impact	0,07	medium_impact	-0,22	medium_impact	-0,43	0,74	0,9	27,88	19,63	N	0,34	N	0,18	polymorphism	1	0,02	rs370460521	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3878	3878	C	G	MI.11940	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	572	191	A	G	gCa/gGa	8,95	1	0	probably_damaging	1	neutral	0,33	neutral	1,75	deleterious	-4,8	deleterious	-3,72	high_impact	3,73	neutral	0,67	damaging	0,05	deleterious	3,97	23,6	0,19	0,45	neutral	0,44	disease	0,77	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,1	high_impact	2,07	0,72	0,85	60,06	10,33	P	0,6	P	0,79	polymorphism	0,99	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3880	3880	G	C	MI.11941	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	574	192	E	Q	Gag/Cag	-3	0	0	probably_damaging	1	neutral	0,25	neutral	2,27	deleterious	-3,47	deleterious	-2,79	high_impact	4,54	neutral	0,7	damaging	0,17	deleterious	3,45	23	0,15	0,4	disease	0,57	disease	0,77	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,01	high_impact	2,78	0,65	0,8	59,43	10,4	N	0,49	N	0,91	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3880	3880	G	A	MI.11942	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	574	192	E	K	Gag/Aag	-3	0	0	probably_damaging	1	neutral	0,25	neutral	2,29	neutral	-2,25	deleterious	-3,71	high_impact	3,6	neutral	0,68	damaging	0,12	deleterious	4,54	24,3	0,06	0,35	disease	0,52	disease	0,88	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,01	medium_impact	1,96	0,77	0,85	59,43	10,4	N	0,39	N	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3881	3881	A	C	MI.11943	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	575	192	E	A	gAg/gCg	7,11	1	0	probably_damaging	1	neutral	0,55	neutral	2,28	deleterious	-3,13	deleterious	-5,57	high_impact	4,2	neutral	0,71	damaging	0,19	deleterious	3,69	23,3	0,04	0,35	disease	0,57	disease	0,74	disease	0,66	disease	0,65	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,32	high_impact	2,48	0,33	0,8	59,43	10,4	P	0,59	P	0,74	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3881	3881	A	G	MI.11944	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	575	192	E	G	gAg/gGg	7,11	1	0	probably_damaging	1	neutral	0,3	neutral	2,24	deleterious	-4,18	deleterious	-6,5	high_impact	4,54	neutral	0,69	damaging	0,19	deleterious	4,24	23,9	0,04	0,35	disease	0,66	disease	0,8	disease	0,7	disease	0,66	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,07	high_impact	2,78	0,21	0,8	59,43	10,4	P	0,66	P	0,61	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3881	3881	A	T	MI.11945	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	575	192	E	V	gAg/gTg	7,11	1	0	probably_damaging	1	neutral	0,49	neutral	2,27	deleterious	-4,31	deleterious	-6,5	high_impact	3,69	neutral	0,75	damaging	0,17	deleterious	4,18	23,8	0,03	0,35	disease	0,74	disease	0,87	disease	0,71	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,27	high_impact	2,03	0,32	0,8	59,43	10,4	P	0,63	P	0,83	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3882	3882	G	C	MI.11946	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	576	192	E	D	gaG/gaC	8,49	1	0	probably_damaging	1	neutral	0,2	neutral	2,3	deleterious	-3,58	deleterious	-2,79	high_impact	3,6	neutral	0,73	damaging	0,15	deleterious	3,75	23,3	0,18	0,45	neutral	0,36	disease	0,74	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	-0,06	medium_impact	1,96	0,6	0,8	59,43	10,4	P	0,64	P	0,9	polymorphism	0,98	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3882	3882	G	T	MI.11947	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	576	192	E	D	gaG/gaT	8,49	1	0	probably_damaging	1	neutral	0,2	neutral	2,3	deleterious	-3,58	deleterious	-2,79	high_impact	3,6	neutral	0,73	damaging	0,15	deleterious	3,91	23,5	0,18	0,45	neutral	0,36	disease	0,74	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	-0,06	medium_impact	1,96	0,6	0,8	59,43	10,4	P	0,64	P	0,9	polymorphism	0,98	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3883	3883	A	G	MI.11948	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	577	193	T	A	Acc/Gcc	0,68	0,99	0	probably_damaging	1	neutral	0,53	neutral	2,61	neutral	-2,19	deleterious	-4,76	medium_impact	3,27	neutral	0,61	damaging	0,09	deleterious	3,46	23	0,24	0,45	neutral	0,31	disease	0,63	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	0,3	medium_impact	1,67	0,18	0,8	60,06	10,43	N	0,39	N	0,65	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3883	3883	A	C	MI.11949	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	577	193	T	P	Acc/Ccc	0,68	0,99	0	probably_damaging	1	neutral	0,2	neutral	2,52	deleterious	-5,07	deleterious	-5,71	high_impact	4,34	neutral	0,64	damaging	0,07	deleterious	3,5	23,1	0,03	0,35	disease	0,63	disease	0,8	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	-0,06	high_impact	2,6	0,22	0,8	60,06	10,43	P	0,54	P	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9088	9088	T	A	MI.1195	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	562	188	S	T	Tct/Act	-4,04	0	0	benign	0	neutral	0,39	neutral	4,38	neutral	-0,13	neutral	1,37	neutral_impact	-0,8	neutral	0,85	neutral	0,97	deleterious	-0,01	2,46	0,35	0,65	neutral	0,22	neutral	0,11	neutral	0,17	neutral	0,31	4	neutral	0,61	deleterious	0,7	neutral	-6	neutral	0,11	high_impact	2,09	medium_impact	0,18	low_impact	-1,78	0,7	0,9	27,88	19,63	N	0,5	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3883	3883	A	T	MI.11950	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	577	193	T	S	Acc/Tcc	0,68	0,99	0	probably_damaging	1	neutral	0,44	neutral	2,58	neutral	-2,89	deleterious	-3,81	medium_impact	2,94	damaging	0,55	damaging	0,07	deleterious	3,28	22,8	0,33	0,5	neutral	0,33	disease	0,71	disease	0,53	disease	0,58	2	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,22	medium_impact	1,38	0,42	0,8	60,06	10,43	N	0,42	N	0,89	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3884	3884	C	A	MI.11951	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	578	193	T	N	aCc/aAc	8,49	1	0	probably_damaging	1	neutral	0,31	neutral	2,53	deleterious	-3,98	deleterious	-4,76	medium_impact	3,19	damaging	0,6	damaging	0,05	deleterious	3,69	23,3	0,28	0,45	disease	0,55	disease	0,83	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,8	low_impact	-3,57	medium_impact	0,08	medium_impact	1,6	0,48	0,8	60,06	10,43	P	0,54	P	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3884	3884	C	T	MI.11952	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	578	193	T	I	aCc/aTc	8,49	1	0	probably_damaging	1	neutral	0,42	neutral	2,6	neutral	-2,26	deleterious	-5,71	medium_impact	3,17	neutral	0,67	damaging	0,06	deleterious	4,07	23,7	0,13	0,4	neutral	0,3	disease	0,86	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-3,57	medium_impact	0,2	medium_impact	1,58	0,41	0,8	60,06	10,43	N	0,5	N	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3884	3884	C	G	MI.11953	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	578	193	T	S	aCc/aGc	8,49	1	0	probably_damaging	1	neutral	0,44	neutral	2,58	neutral	-2,89	deleterious	-3,81	medium_impact	2,94	damaging	0,55	damaging	0,07	deleterious	3,55	23,1	0,33	0,5	neutral	0,33	disease	0,71	disease	0,53	disease	0,58	2	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,22	medium_impact	1,38	0,42	0,8	60,06	10,43	P	0,55	P	0,89	polymorphism	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3886	3886	A	T	MI.11954	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	580	194	N	Y	Aac/Tac	-12,42	0	0	probably_damaging	1	neutral	1	neutral	2,49	deleterious	-4,32	deleterious	-7,6	high_impact	4,02	neutral	0,71	damaging	0,07	deleterious	3,81	23,4	0,11	0,4	disease	0,65	disease	0,84	disease	0,67	disease	0,68	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,82	low_impact	-3,57	high_impact	1,96	high_impact	2,32	0,13	0,8	58,81	10,46	N	0,25	N	1	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3886	3886	A	G	MI.11955	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	580	194	N	D	Aac/Gac	-12,42	0	0	probably_damaging	1	neutral	0,23	neutral	2,58	neutral	-1,66	deleterious	-4,75	high_impact	4,48	neutral	0,73	damaging	0,1	deleterious	3,96	23,6	0,61	0,65	neutral	0,35	disease	0,71	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,74	low_impact	-3,57	medium_impact	-0,02	high_impact	2,72	0,24	0,8	58,81	10,46	N	0,49	N	0,97	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3886	3886	A	C	MI.11956	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	580	194	N	H	Aac/Cac	-12,42	0	0	probably_damaging	1	neutral	0,53	neutral	2,53	neutral	-2,73	deleterious	-4,75	medium_impact	3,16	neutral	0,69	damaging	0,07	deleterious	3,15	22,6	0,41	0,5	disease	0,53	disease	0,76	disease	0,67	disease	0,64	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,78	low_impact	-3,57	medium_impact	0,3	medium_impact	1,57	0,14	0,8	58,81	10,46	N	0,23	N	0,97	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3887	3887	A	G	MI.11957	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	581	194	N	S	aAc/aGc	6,65	1	0	probably_damaging	1	neutral	0,55	neutral	2,56	neutral	-2,05	deleterious	-4,75	high_impact	3,85	neutral	0,79	damaging	0,12	deleterious	3,74	23,3	0,53	0,6	neutral	0,32	disease	0,75	disease	0,61	disease	0,64	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	0,32	high_impact	2,17	0,17	0,8	58,81	10,46	N	0,53	P	0,9	polymorphism	0,99	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3887	3887	A	C	MI.11958	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	581	194	N	T	aAc/aCc	6,65	1	0	probably_damaging	1	neutral	0,51	neutral	2,53	neutral	-2,52	deleterious	-5,69	high_impact	4,48	neutral	0,74	damaging	0,11	deleterious	3,99	23,6	0,29	0,45	neutral	0,38	disease	0,76	disease	0,56	disease	0,64	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	0,29	high_impact	2,72	0,27	0,8	58,81	10,46	P	0,55	P	0,96	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3887	3887	A	T	MI.11959	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	581	194	N	I	aAc/aTc	6,65	1	0	probably_damaging	1	neutral	0,42	neutral	2,49	deleterious	-3,97	deleterious	-8,55	high_impact	4,13	neutral	0,73	damaging	0,09	deleterious	4,59	24,4	0,1	0,4	disease	0,59	disease	0,87	disease	0,62	disease	0,67	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,2	high_impact	2,42	0,14	0,8	58,81	10,46	P	0,61	P	1	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9088	9088	T	G	MI.1196	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	562	188	S	A	Tct/Gct	-4,04	0	0	benign	0	neutral	0,29	neutral	4,39	neutral	-0,07	neutral	0,44	neutral_impact	-0,62	neutral	0,97	neutral	0,97	deleterious	0,42	6,77	0,46	0,65	neutral	0,34	neutral	0,15	neutral	0,2	neutral	0,3	4	neutral	0,71	deleterious	0,65	neutral	-6	neutral	0,13	high_impact	2,09	medium_impact	0,07	low_impact	-1,63	0,76	0,9	27,88	19,63	N	0,5	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3888	3888	C	G	MI.11960	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	582	194	N	K	aaC/aaG	8,49	1	0	probably_damaging	1	neutral	0,29	neutral	2,61	neutral	-1,34	deleterious	-5,7	high_impact	3,5	neutral	0,76	damaging	0,1	deleterious	4,07	23,7	0,42	0,55	neutral	0,26	disease	0,79	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,06	medium_impact	1,87	0,33	0,8	58,81	10,46	P	0,56	P	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3888	3888	C	A	MI.11961	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	582	194	N	K	aaC/aaA	8,49	1	0	probably_damaging	1	neutral	0,29	neutral	2,61	neutral	-1,34	deleterious	-5,7	high_impact	3,5	neutral	0,76	damaging	0,1	deleterious	4,48	24,2	0,42	0,55	neutral	0,26	disease	0,79	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,06	medium_impact	1,87	0,33	0,8	58,81	10,46	P	0,56	P	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3889	3889	C	G	MI.11962	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	583	195	R	G	Cga/Gga	-1,39	0	0	probably_damaging	1	neutral	0,44	neutral	1,63	deleterious	-5,9	deleterious	-6,66	high_impact	4,91	neutral	0,75	damaging	0,09	deleterious	4,28	24	0,04	0,35	disease	0,8	disease	0,8	disease	0,76	disease	0,67	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,22	high_impact	3,1	0,12	0,8	59,12	10,38	P	0,66	P	1	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3889	3889	C	T	MI.11963	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	583	195	R	W	Cga/Tga	-1,39	0	0	probably_damaging	1	neutral	0,18	neutral	1,6	deleterious	-8,5	deleterious	-7,61	high_impact	4,56	neutral	0,62	damaging	0,06	deleterious	5,26	25,7	0,05	0,35	disease	0,94	disease	0,86	disease	0,79	disease	0,63	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	-0,09	high_impact	2,79	0,62	0,8	59,12	10,38	N	0,49	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3890	3890	G	A	MI.11964	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	584	195	R	Q	cGa/cAa	2,75	0,98	0	probably_damaging	1	neutral	0,49	neutral	1,65	deleterious	-5,17	deleterious	-3,8	high_impact	4,56	neutral	0,72	damaging	0,1	deleterious	4,56	24,4	0,17	0,45	disease	0,58	disease	0,84	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,27	high_impact	2,79	0,81	0,85	59,12	10,38	P	0,73	P	1	disease_causing_automatic	0	0,48	rs587776434	Pathogenic	Leigh_syndrome	RCV000144000.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	G3890A	Progressive encephalomyopathy/LS/optic atrophy	-	+	Cfrm	3
chrM	3890	3890	G	C	MI.11965	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	584	195	R	P	cGa/cCa	2,75	0,98	0	probably_damaging	1	neutral	0,31	neutral	1,61	deleterious	-6,63	deleterious	-6,66	high_impact	4,91	neutral	0,63	damaging	0,06	deleterious	4,3	24	0,02	0,35	disease	0,84	disease	0,87	disease	0,75	disease	0,64	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	0,08	high_impact	3,1	0,1	0,8	59,12	10,38	P	0,71	P	1	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3890	3890	G	T	MI.11966	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	584	195	R	L	cGa/cTa	2,75	0,98	0	probably_damaging	1	neutral	0,99	neutral	1,63	deleterious	-5,7	deleterious	-6,66	high_impact	4,91	neutral	0,75	damaging	0,09	deleterious	4,31	24	0,04	0,35	disease	0,75	disease	0,9	disease	0,77	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	1,39	high_impact	3,1	0,02	0,8	59,12	10,38	P	0,72	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3892	3892	A	G	MI.11967	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	586	196	T	A	Acc/Gcc	-2,08	0	0	benign	0,01	neutral	0,9	neutral	2,91	neutral	0,7	neutral	2,95	neutral_impact	-0,97	neutral	0,65	neutral	0,86	neutral	-1,06	0,01	0,34	0,5	neutral	0,14	neutral	0,05	neutral	0,23	neutral	0,2	6	neutral	0,06	deleterious	0,95	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	0,81	low_impact	-2,04	0,56	0,8	16,98	21,4	N	0,33	N	0	polymorphism	1	0,01	rs879131781	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3892	3892	A	T	MI.11968	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	586	196	T	S	Acc/Tcc	-2,08	0	0	benign	0,32	neutral	0,78	neutral	2,8	neutral	-0,32	neutral	0,54	neutral_impact	0,16	neutral	0,78	neutral	0,76	neutral	1,53	13,47	0,44	0,55	neutral	0,22	neutral	0,37	neutral	0,3	neutral	0,42	2	neutral	0,21	deleterious	0,73	neutral	-6	neutral	0,3	medium_impact	-0,44	medium_impact	0,58	low_impact	-1,05	0,65	0,8	16,98	21,4	N	0,22	N	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3892	3892	A	C	MI.11969	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	586	196	T	P	Acc/Ccc	-2,08	0	0	possibly_damaging	0,72	neutral	0,28	neutral	2,75	neutral	-1,15	neutral	-1,39	low_impact	1,56	damaging	0,57	neutral	0,47	deleterious	1,86	15,32	0,06	0,35	neutral	0,22	disease	0,82	disease	0,6	disease	0,73	5	neutral	0,8	neutral	0,28	neutral	-3	deleterious	0,59	low_impact	-1,14	medium_impact	0,05	medium_impact	0,17	0,37	0,8	16,98	21,4	N	0,35	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9089	9089	C	T	MI.1197	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	563	188	S	F	tCt/tTt	-0,57	0	0	benign	0,07	neutral	0,24	neutral	4,39	neutral	-0,05	neutral	-1,09	neutral_impact	-0,32	neutral	0,89	neutral	0,54	deleterious	2,37	18,65	0,27	0,65	neutral	0,43	disease	0,62	neutral	0,47	disease	0,5	0	neutral	0,74	deleterious	0,59	neutral	-6	neutral	0,21	medium_impact	0,31	medium_impact	0,01	low_impact	-1,37	0,6	0,9	27,88	19,63	N	0,36	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3893	3893	C	A	MI.11970	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	587	196	T	N	aCc/aAc	2,98	0,99	0	possibly_damaging	0,78	neutral	0,53	neutral	2,78	neutral	-1,37	neutral	-2,13	medium_impact	2,17	damaging	0,57	neutral	0,64	deleterious	2,12	16,98	0,4	0,5	neutral	0,27	disease	0,73	disease	0,64	disease	0,69	4	neutral	0,75	neutral	0,38	NA	0	deleterious	0,58	low_impact	-1,27	medium_impact	0,3	medium_impact	0,71	0,52	0,8	16,98	21,4	P	0,51	P	0,61	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3893	3893	C	G	MI.11971	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	587	196	T	S	aCc/aGc	2,98	0,99	0	benign	0,32	neutral	0,78	neutral	2,8	neutral	-0,32	neutral	0,54	neutral_impact	0,16	neutral	0,78	neutral	0,76	neutral	1,67	14,22	0,44	0,55	neutral	0,22	neutral	0,37	neutral	0,3	neutral	0,42	2	neutral	0,21	deleterious	0,73	neutral	-6	neutral	0,3	medium_impact	-0,44	medium_impact	0,58	low_impact	-1,05	0,65	0,8	16,98	21,4	N	0,38	N	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3893	3893	C	T	MI.11972	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	587	196	T	I	aCc/aTc	2,98	0,99	0	possibly_damaging	0,52	neutral	0,22	neutral	2,77	neutral	-0,74	neutral	-1,42	low_impact	1,79	neutral	0,61	neutral	0,6	deleterious	2,19	17,47	0,19	0,45	neutral	0,22	disease	0,63	disease	0,59	disease	0,68	4	neutral	0,76	neutral	0,35	neutral	-3	deleterious	0,47	medium_impact	-0,78	medium_impact	-0,03	medium_impact	0,38	0,57	0,8	16,98	21,4	P	0,58	P	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3895	3895	C	T	MI.11973	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	589	197	P	S	Ccc/Tcc	-5,52	0	0	probably_damaging	1	neutral	0,82	neutral	1,21	deleterious	-7,13	deleterious	-7,61	high_impact	4,88	neutral	0,73	damaging	0,11	deleterious	4,03	23,6	0,06	0,35	disease	0,89	disease	0,77	disease	0,67	disease	0,64	3	deleterious	1	neutral	0,41	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,64	high_impact	3,07	0,08	0,8	59,43	10,41	P	0,58	P	0,74	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3895	3895	C	G	MI.11974	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	589	197	P	A	Ccc/Gcc	-5,52	0	0	probably_damaging	1	neutral	1	neutral	1,22	deleterious	-6,91	deleterious	-7,61	high_impact	4,88	neutral	0,71	damaging	0,12	deleterious	3,23	22,8	0,08	0,35	disease	0,87	disease	0,56	disease	0,71	disease	0,68	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,83	low_impact	-3,57	high_impact	1,96	high_impact	3,07	0,61	0,8	59,43	10,41	N	0,57	P	0,78	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3895	3895	C	A	MI.11975	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	589	197	P	T	Ccc/Acc	-5,52	0	0	probably_damaging	1	neutral	0,8	neutral	1,19	deleterious	-7,5	deleterious	-7,61	high_impact	4,88	neutral	0,68	damaging	0,1	deleterious	3,83	23,4	0,06	0,35	disease	0,91	disease	0,73	disease	0,7	disease	0,64	3	deleterious	1	neutral	0,4	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,61	high_impact	3,07	0,45	0,8	59,43	10,41	N	0,56	P	0,91	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3896	3896	C	A	MI.11976	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	590	197	P	H	cCc/cAc	5,5	1	0	probably_damaging	1	neutral	0,57	neutral	1,17	deleterious	-7,97	deleterious	-8,56	high_impact	4,88	neutral	0,71	damaging	0,09	deleterious	4,17	23,8	0,04	0,35	disease	0,97	disease	0,76	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	0,34	high_impact	3,07	0,2	0,8	59,43	10,41	P	0,69	P	0,69	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3896	3896	C	G	MI.11977	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	590	197	P	R	cCc/cGc	5,5	1	0	probably_damaging	1	neutral	0,69	neutral	1,18	deleterious	-7,99	deleterious	-8,56	high_impact	4,34	neutral	0,81	damaging	0,12	deleterious	3,73	23,3	0,04	0,35	disease	0,94	disease	0,77	disease	0,74	disease	0,66	3	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,47	high_impact	2,6	0,17	0,8	59,43	10,41	P	0,59	P	0,71	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3896	3896	C	T	MI.11978	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	590	197	P	L	cCc/cTc	5,5	1	0	probably_damaging	1	neutral	0,84	neutral	1,19	deleterious	-6,87	deleterious	-9,51	high_impact	4,34	neutral	0,68	damaging	0,08	deleterious	4,55	24,3	0,03	0,35	disease	0,94	disease	0,76	disease	0,66	disease	0,65	3	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,68	high_impact	2,6	0,52	0,8	59,43	10,41	P	0,58	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3898	3898	T	A	MI.11979	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	592	198	F	I	Ttc/Atc	-11,27	0	0	probably_damaging	1	neutral	0,44	neutral	1,69	deleterious	-4,92	deleterious	-5,72	high_impact	4,84	neutral	0,74	damaging	0,17	deleterious	4,52	24,3	0,06	0,35	disease	0,63	disease	0,75	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,22	high_impact	3,04	0,18	0,8	59,75	10,34	P	0,65	P	0,97	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9089	9089	C	G	MI.1198	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	563	188	S	C	tCt/tGt	-0,57	0	0	benign	0,43	deleterious	0,04	neutral	4,3	neutral	-2,51	neutral	-0,78	low_impact	1,12	neutral	0,76	neutral	0,42	deleterious	2,06	16,57	0,24	0,65	disease	0,64	disease	0,55	neutral	0,38	neutral	0,5	0	neutral	0,95	neutral	0,31	neutral	-2	deleterious	0,44	medium_impact	-0,64	medium_impact	-0,49	medium_impact	-0,14	0,69	0,9	27,88	19,63	N	0,38	N	0,13	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3898	3898	T	C	MI.11980	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	592	198	F	L	Ttc/Ctc	-11,27	0	0	probably_damaging	1	neutral	0,73	neutral	1,75	deleterious	-3,84	deleterious	-5,72	high_impact	3,52	neutral	0,73	damaging	0,15	deleterious	4,17	23,8	0,06	0,35	disease	0,53	disease	0,75	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,52	medium_impact	1,89	0,23	0,8	59,75	10,34	N	0,32	N	0,92	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3898	3898	T	G	MI.11981	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	592	198	F	V	Ttc/Gtc	-11,27	0	0	probably_damaging	1	neutral	0,56	neutral	1,69	deleterious	-4,94	deleterious	-6,67	high_impact	4,14	neutral	0,64	damaging	0,15	deleterious	4,26	23,9	0,06	0,35	neutral	0,5	disease	0,81	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,33	high_impact	2,43	0,19	0,8	59,75	10,34	N	0,32	N	0,98	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3899	3899	T	A	MI.11982	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	593	198	F	Y	tTc/tAc	7,34	1	0	probably_damaging	1	neutral	1	neutral	1,75	deleterious	-3,94	deleterious	-2,86	high_impact	3,8	neutral	0,73	damaging	0,14	deleterious	4,37	24,1	0,09	0,35	disease	0,55	disease	0,73	disease	0,67	disease	0,65	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,8	low_impact	-3,57	high_impact	1,96	high_impact	2,13	0,37	0,8	59,75	10,34	P	0,56	P	0,88	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3899	3899	T	C	MI.11983	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	593	198	F	S	tTc/tCc	7,34	1	0	probably_damaging	1	neutral	0,58	neutral	1,66	deleterious	-6,03	deleterious	-7,63	high_impact	4,03	neutral	0,77	damaging	0,19	deleterious	4,36	24,1	0,03	0,35	disease	0,66	disease	0,86	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,35	high_impact	2,33	0,06	0,8	59,75	10,34	P	0,57	P	0,98	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3899	3899	T	G	MI.11984	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	593	198	F	C	tTc/tGc	7,34	1	0	probably_damaging	1	neutral	0,19	neutral	1,64	deleterious	-7,58	deleterious	-7,63	high_impact	4,29	neutral	0,72	damaging	0,13	deleterious	4,24	23,9	0,03	0,35	disease	0,89	disease	0,83	disease	0,74	disease	0,62	2	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,08	high_impact	2,56	0,1	0,8	59,75	10,34	P	0,65	P	1	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3900	3900	C	G	MI.11985	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	594	198	F	L	ttC/ttG	7,34	1	0	probably_damaging	1	neutral	0,73	neutral	1,75	deleterious	-3,84	deleterious	-5,72	high_impact	3,52	neutral	0,73	damaging	0,15	deleterious	4,45	24,2	0,06	0,35	disease	0,53	disease	0,75	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,52	medium_impact	1,89	0,23	0,8	59,75	10,34	N	0,56	P	0,92	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3900	3900	C	A	MI.11986	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	594	198	F	L	ttC/ttA	7,34	1	0	probably_damaging	1	neutral	0,73	neutral	1,75	deleterious	-3,84	deleterious	-5,72	high_impact	3,52	neutral	0,73	damaging	0,15	deleterious	4,72	24,6	0,06	0,35	disease	0,53	disease	0,75	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,52	medium_impact	1,89	0,23	0,8	59,75	10,34	P	0,57	P	0,92	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3901	3901	G	C	MI.11987	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	595	199	D	H	Gac/Cac	-3,92	0	0	probably_damaging	1	neutral	0,12	neutral	1,55	deleterious	-6,19	deleterious	-6,67	high_impact	4,88	neutral	0,62	damaging	0,26	deleterious	3,71	23,3	0,05	0,35	disease	0,92	disease	0,85	disease	0,73	disease	0,61	2	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	-0,21	high_impact	3,07	0,32	0,8	59,75	10,21	P	0,6	P	0,99	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3901	3901	G	T	MI.11988	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	595	199	D	Y	Gac/Tac	-3,92	0	0	probably_damaging	1	neutral	0,05	neutral	1,54	deleterious	-8,2	deleterious	-8,57	high_impact	4,88	neutral	0,67	damaging	0,28	deleterious	4,01	23,6	0,03	0,35	disease	0,95	disease	0,92	disease	0,74	disease	0,61	2	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	-0,44	high_impact	3,07	0,06	0,8	59,75	10,21	P	0,56	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3901	3901	G	A	MI.11989	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	595	199	D	N	Gac/Aac	-3,92	0	0	probably_damaging	1	neutral	0,53	neutral	1,59	deleterious	-4,74	deleterious	-4,76	high_impact	4,53	neutral	0,68	neutral	0,35	deleterious	4,3	24	0,34	0,5	disease	0,81	disease	0,83	disease	0,69	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,3	high_impact	2,77	0,43	0,8	59,75	10,21	N	0,51	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9089	9089	C	A	MI.1199	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	563	188	S	Y	tCt/tAt	-0,57	0	0	benign	0,25	neutral	0,25	neutral	4,33	neutral	-1,15	neutral	-1,26	neutral_impact	0,67	neutral	0,92	neutral	0,61	deleterious	2,32	18,33	0,23	0,65	neutral	0,5	disease	0,57	neutral	0,46	neutral	0,49	0	neutral	0,7	deleterious	0,5	neutral	-6	neutral	0,32	medium_impact	-0,3	medium_impact	0,02	medium_impact	-0,52	0,76	0,9	27,88	19,63	N	0,34	N	0,03	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3902	3902	A	T	MI.11990	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	596	199	D	V	gAc/gTc	7,11	1	0	probably_damaging	1	neutral	0,27	neutral	1,55	deleterious	-7,09	deleterious	-8,57	high_impact	4,33	neutral	0,61	neutral	0,33	deleterious	4,45	24,2	0,03	0,35	disease	0,93	disease	0,89	disease	0,7	disease	0,6	2	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	0,03	high_impact	2,59	0,05	0,8	59,75	10,21	P	0,66	P	1	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3902	3902	A	C	MI.11991	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	596	199	D	A	gAc/gCc	7,11	1	0	probably_damaging	1	neutral	0,73	neutral	1,58	deleterious	-5,75	deleterious	-7,62	high_impact	4,88	neutral	0,66	neutral	0,39	deleterious	4,26	23,9	0,05	0,35	disease	0,85	disease	0,83	disease	0,68	disease	0,63	3	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,52	high_impact	3,07	0,14	0,8	59,75	10,21	P	0,71	P	0,94	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3902	3902	A	G	MI.11992	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	596	199	D	G	gAc/gGc	7,11	1	0	probably_damaging	1	neutral	0,34	neutral	1,57	deleterious	-6,25	deleterious	-6,67	high_impact	4,88	neutral	0,64	neutral	0,38	deleterious	4,64	24,5	0,05	0,35	disease	0,84	disease	0,86	disease	0,7	disease	0,64	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,11	high_impact	3,07	0,19	0,8	59,75	10,21	P	0,75	P	0,99	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3903	3903	C	G	MI.11993	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	597	199	D	E	gaC/gaG	6,65	1	0	probably_damaging	1	neutral	1	neutral	1,64	deleterious	-4,08	deleterious	-3,81	high_impact	4,88	neutral	0,7	neutral	0,35	deleterious	4,02	23,6	0,13	0,4	disease	0,72	disease	0,79	disease	0,67	disease	0,65	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,85	low_impact	-3,57	high_impact	1,96	high_impact	3,07	0,36	0,8	59,75	10,21	P	0,76	P	0,95	polymorphism	0,97	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3903	3903	C	A	MI.11994	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	597	199	D	E	gaC/gaA	6,65	1	0	probably_damaging	1	neutral	1	neutral	1,64	deleterious	-4,08	deleterious	-3,81	high_impact	4,88	neutral	0,7	neutral	0,35	deleterious	4,36	24,1	0,13	0,4	disease	0,72	disease	0,79	disease	0,67	disease	0,65	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,85	low_impact	-3,57	high_impact	1,96	high_impact	3,07	0,36	0,8	59,75	10,21	P	0,76	P	0,95	polymorphism	0,97	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3904	3904	C	A	MI.11995	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	598	200	L	I	Ctt/Att	-1,39	0	0	probably_damaging	1	neutral	0,37	neutral	2,28	neutral	-2,68	neutral	-1,9	medium_impact	3,3	neutral	0,61	damaging	0,06	deleterious	4,35	24,1	0,37	0,5	neutral	0,27	neutral	0,5	disease	0,54	disease	0,57	1	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,15	medium_impact	1,69	0,41	0,8	58,81	10,38	N	0,36	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3904	3904	C	G	MI.11996	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	598	200	L	V	Ctt/Gtt	-1,39	0	0	probably_damaging	1	neutral	0,5	neutral	2,28	neutral	-2,78	deleterious	-2,85	medium_impact	3,15	damaging	0,57	damaging	0,05	deleterious	3,52	23,1	0,31	0,45	neutral	0,25	neutral	0,48	disease	0,58	disease	0,52	0	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,28	medium_impact	1,56	0,34	0,8	58,81	10,38	N	0,28	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3904	3904	C	T	MI.11997	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	598	200	L	F	Ctt/Ttt	-1,39	0	0	probably_damaging	1	neutral	0,46	neutral	2,33	neutral	-2,18	deleterious	-3,78	low_impact	1,88	damaging	0,57	damaging	0,04	deleterious	4,06	23,7	0,34	0,5	neutral	0,33	neutral	0,2	neutral	0,24	neutral	0,34	3	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,71	low_impact	-3,57	medium_impact	0,24	medium_impact	0,45	0,39	0,8	58,81	10,38	N	0,29	N	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3905	3905	T	C	MI.11998	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	599	200	L	P	cTt/cCt	-0,01	0	0	probably_damaging	1	neutral	0,37	neutral	2,18	deleterious	-5,65	deleterious	-6,65	high_impact	3,85	damaging	0,44	damaging	0,04	deleterious	3,99	23,6	0,04	0,35	disease	0,67	disease	0,78	disease	0,6	disease	0,64	3	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,15	high_impact	2,17	0,12	0,8	58,81	10,38	N	0,38	N	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3905	3905	T	A	MI.11999	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	599	200	L	H	cTt/cAt	-0,01	0	0	probably_damaging	1	neutral	0,38	neutral	2,18	deleterious	-5,38	deleterious	-6,65	high_impact	4,2	damaging	0,54	damaging	0,04	deleterious	4,17	23,8	0,07	0,35	disease	0,66	disease	0,73	disease	0,68	disease	0,64	3	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,16	high_impact	2,48	0,21	0,8	58,81	10,38	N	0,31	N	0,97	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8531	8531	A	C	MI.12	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	5	2	N	T	aAc/aCc	6,84	1	0	probably_damaging	0,97	neutral	0,46	neutral	4,67	neutral	-0,37	deleterious	-2,81	low_impact	1,05	neutral	0,79	neutral	0,61	deleterious	3,61	23,2	0,71	0,75	neutral	0,41	neutral	0,08	neutral	0,06	neutral	0,28	4	neutral	0,97	neutral	0,25	neutral	-2	deleterious	0,63	low_impact	-2,19	medium_impact	0,25	medium_impact	-0,2	0,38	0,9	41,59	7,23	P	0,56	P	0,96	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8582	8582	C	G	MI.120	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	56	19	A	G	gCc/gGc	-0,57	0	0	probably_damaging	0,99	deleterious	0	neutral	4,59	neutral	-2,11	deleterious	-2,92	low_impact	0,8	neutral	0,79	neutral	0,59	deleterious	3,79	23,4	0,19	0,65	disease	0,56	neutral	0,47	neutral	0,44	disease	0,62	2	deleterious	1	neutral	0,01	deleterious	2	deleterious	0,73	low_impact	-2,65	low_impact	-1,4	medium_impact	-0,41	0,68	0,9	29,65	29,28	N	0,33	N	0,52	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9091	9091	A	G	MI.1200	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	565	189	T	A	Aca/Gca	-5,66	0	0,01	benign	0,01	neutral	1	neutral	4,51	neutral	0,04	neutral	0,63	neutral_impact	-1,18	neutral	0,91	neutral	0,96	neutral	-1,07	0,01	0,64	0,7	neutral	0,3	neutral	0,07	neutral	0,27	neutral	0,21	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,12	medium_impact	1,14	high_impact	1,98	low_impact	-2,11	0,46	0,9	29,2	23,91	N	0,28	N	0	polymorphism	1	0,01	rs1057520079	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3905	3905	T	G	MI.12000	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	599	200	L	R	cTt/cGt	-0,01	0	0	probably_damaging	1	neutral	0,66	neutral	2,19	deleterious	-4,78	deleterious	-5,7	high_impact	4,54	damaging	0,47	damaging	0,04	deleterious	4,28	24	0,04	0,35	disease	0,57	disease	0,78	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	0,44	high_impact	2,78	0,17	0,8	58,81	10,38	N	0,46	N	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3907	3907	G	A	MI.12001	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	601	201	A	T	Gcc/Acc	-10,81	0	0	benign	0	neutral	0,59	neutral	2,78	neutral	-1,64	neutral	4,22	neutral_impact	-0,7	damaging	0,59	neutral	0,78	neutral	-0,33	0,58	0,31	0,45	neutral	0,21	neutral	0,06	neutral	0,13	neutral	0,23	5	neutral	0,41	deleterious	0,8	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,36	low_impact	-1,8	0,5	0,8	20,13	14,24	N	0,44	N	0,05	polymorphism	1	0,01	rs876661354	Uncertain significance	not_specified	RCV000223871.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	3907	3907	G	T	MI.12002	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	601	201	A	S	Gcc/Tcc	-10,81	0	0	benign	0,01	neutral	0,74	neutral	2,73	neutral	-1,16	neutral	0,77	neutral_impact	0,36	neutral	0,78	neutral	0,79	deleterious	1,85	15,26	0,37	0,5	neutral	0,26	neutral	0,48	neutral	0,21	neutral	0,29	4	neutral	0,24	deleterious	0,87	neutral	-6	neutral	0,18	medium_impact	1,12	medium_impact	0,53	medium_impact	-0,87	0,31	0,8	20,13	14,24	N	0,31	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3907	3907	G	C	MI.12003	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	601	201	A	P	Gcc/Ccc	-10,81	0	0	benign	0,04	neutral	0,28	neutral	2,81	neutral	0,72	neutral	-1,1	neutral_impact	0,3	damaging	0,55	neutral	0,44	deleterious	1,97	16,02	0,14	0,4	neutral	0,15	disease	0,73	neutral	0,22	neutral	0,18	6	neutral	0,7	deleterious	0,62	neutral	-6	neutral	0,2	medium_impact	0,55	medium_impact	0,05	medium_impact	-0,93	0,44	0,8	20,13	14,24	N	0,43	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3908	3908	C	G	MI.12004	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	602	201	A	G	gCc/gGc	3,21	0,98	0	benign	0,01	neutral	0,39	neutral	2,65	neutral	-2,89	neutral	-1,98	low_impact	1,8	damaging	0,49	neutral	0,64	deleterious	2,14	17,11	0,33	0,5	neutral	0,44	disease	0,51	neutral	0,45	neutral	0,5	0	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,19	medium_impact	1,12	medium_impact	0,17	medium_impact	0,38	0,59	0,8	20,13	14,24	P	0,65	P	0,31	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3908	3908	C	T	MI.12005	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	602	201	A	V	gCc/gTc	3,21	0,98	0	benign	0	neutral	0,31	neutral	2,68	neutral	-1,16	neutral	-0,08	low_impact	1,04	damaging	0,56	neutral	0,78	deleterious	2,66	20,6	0,27	0,45	neutral	0,37	disease	0,5	neutral	0,48	neutral	0,46	1	neutral	0,69	deleterious	0,66	neutral	-6	neutral	0,18	high_impact	2,07	medium_impact	0,08	medium_impact	-0,28	0,53	0,8	20,13	14,24	P	0,62	P	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3908	3908	C	A	MI.12006	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	602	201	A	D	gCc/gAc	3,21	0,98	0	benign	0,02	neutral	0,63	neutral	2,63	neutral	-2,82	neutral	-1,18	medium_impact	2,73	neutral	0,61	neutral	0,52	deleterious	2,64	20,5	0,09	0,35	neutral	0,37	disease	0,77	disease	0,54	disease	0,67	3	neutral	0,33	deleterious	0,81	neutral	-3	neutral	0,22	medium_impact	0,84	medium_impact	0,4	medium_impact	1,2	0,23	0,8	20,13	14,24	N	0,52	P	0,21	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3910	3910	G	C	MI.12007	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	604	202	E	Q	Gaa/Caa	-4,15	0	0	probably_damaging	1	neutral	0,64	neutral	1,75	deleterious	-5,04	deleterious	-2,85	high_impact	4,8	neutral	0,68	damaging	0,13	deleterious	3,49	23,1	0,33	0,5	neutral	0,44	disease	0,78	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,42	high_impact	3	0,51	0,8	60,06	10,22	P	0,63	P	0,91	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3910	3910	G	A	MI.12008	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	604	202	E	K	Gaa/Aaa	-4,15	0	0	probably_damaging	1	neutral	0,94	neutral	1,77	deleterious	-4,61	deleterious	-3,79	high_impact	4,11	neutral	0,74	damaging	0,13	deleterious	4,56	24,4	0,11	0,4	neutral	0,35	disease	0,87	disease	0,63	disease	0,68	4	deleterious	1	deleterious	0,47	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,94	high_impact	2,4	0,68	0,85	60,06	10,22	N	0,34	N	0,99	polymorphism	1	0,29	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	3911	3911	A	T	MI.12009	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	605	202	E	V	gAa/gTa	8,95	1	0	probably_damaging	1	neutral	0,48	neutral	1,73	deleterious	-5,97	deleterious	-6,65	high_impact	4,11	neutral	0,63	damaging	0,12	deleterious	4,39	24,1	0,08	0,35	neutral	0,47	disease	0,87	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,26	high_impact	2,4	0,31	0,8	60,06	10,22	P	0,57	P	0,83	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9091	9091	A	C	MI.1201	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	565	189	T	P	Aca/Cca	-5,66	0	0,01	possibly_damaging	0,44	neutral	0,1	neutral	4,35	neutral	-1,83	neutral	-2,17	low_impact	1,3	neutral	0,9	neutral	0,61	deleterious	3,13	22,6	0,17	0,65	neutral	0,39	disease	0,83	disease	0,67	disease	0,81	6	neutral	0,89	neutral	0,33	neutral	-3	deleterious	0,52	medium_impact	-0,66	medium_impact	-0,25	medium_impact	0,02	0,68	0,9	29,2	23,91	N	0,4	N	0,24	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3911	3911	A	C	MI.12010	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	605	202	E	A	gAa/gCa	8,95	1	0	probably_damaging	1	neutral	0,89	neutral	1,75	deleterious	-4,91	deleterious	-5,7	high_impact	4,8	neutral	0,69	damaging	0,15	deleterious	3,81	23,4	0,09	0,35	neutral	0,36	disease	0,77	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	0,78	high_impact	3	0,43	0,8	60,06	10,22	P	0,66	P	0,74	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3911	3911	A	G	MI.12011	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	605	202	E	G	gAa/gGa	8,95	1	0	probably_damaging	1	neutral	0,48	neutral	1,74	deleterious	-5,26	deleterious	-6,65	high_impact	4,8	neutral	0,69	damaging	0,17	deleterious	4,39	24,1	0,11	0,4	disease	0,58	disease	0,79	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,26	high_impact	3	0,3	0,8	60,06	10,22	P	0,72	P	0,61	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3912	3912	A	T	MI.12012	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	606	202	E	D	gaA/gaT	6,65	1	0	probably_damaging	1	neutral	0,64	neutral	1,8	deleterious	-3,99	deleterious	-2,85	high_impact	4,11	neutral	0,77	damaging	0,15	deleterious	3,96	23,6	0,27	0,45	neutral	0,47	disease	0,75	disease	0,59	disease	0,64	3	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,42	high_impact	2,4	0,46	0,8	60,06	10,22	P	0,58	P	0,9	polymorphism	0,98	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3912	3912	A	C	MI.12013	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	606	202	E	D	gaA/gaC	6,65	1	0	probably_damaging	1	neutral	0,64	neutral	1,8	deleterious	-3,99	deleterious	-2,85	high_impact	4,11	neutral	0,77	damaging	0,15	deleterious	3,84	23,4	0,27	0,45	neutral	0,47	disease	0,75	disease	0,59	disease	0,64	3	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,42	high_impact	2,4	0,46	0,8	60,06	10,22	P	0,58	P	0,9	polymorphism	0,98	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3913	3913	G	T	MI.12014	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	607	203	G	W	Ggg/Tgg	-0,24	0,49	0	probably_damaging	1	neutral	0,11	neutral	2,42	deleterious	-6,8	deleterious	-7,61	high_impact	4,54	neutral	0,66	damaging	0,1	deleterious	4,53	24,3	0,04	0,35	disease	0,91	disease	0,88	disease	0,71	disease	0,61	2	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,23	high_impact	2,78	0,08	0,8	58,49	10,36	N	0,48	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3913	3913	G	C	MI.12015	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	607	203	G	R	Ggg/Cgg	-0,24	0,49	0	probably_damaging	1	neutral	0,62	neutral	2,44	deleterious	-3,77	deleterious	-7,61	high_impact	4,19	neutral	0,69	damaging	0,09	deleterious	4,08	23,7	0,05	0,35	disease	0,66	disease	0,87	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,39	high_impact	2,47	0,43	0,8	58,49	10,36	N	0,38	N	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3914	3914	G	A	MI.12016	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	608	203	G	E	gGg/gAg	8,95	1	0	probably_damaging	1	neutral	1	neutral	2,46	deleterious	-3,18	deleterious	-7,61	high_impact	3,99	neutral	0,68	damaging	0,11	deleterious	4,07	23,7	0,05	0,35	disease	0,63	disease	0,87	disease	0,72	disease	0,69	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,85	low_impact	-3,57	high_impact	1,96	high_impact	2,3	0,21	0,8	58,49	10,36	N	0,53	P	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3914	3914	G	C	MI.12017	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	608	203	G	A	gGg/gCg	8,95	1	0	probably_damaging	1	neutral	0,9	neutral	2,92	neutral	0,41	deleterious	-5,7	medium_impact	2	neutral	0,63	damaging	0,14	deleterious	3,23	22,8	0,14	0,4	neutral	0,16	disease	0,7	neutral	0,37	neutral	0,16	7	deleterious	1	neutral	0,45	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,81	medium_impact	0,56	0,34	0,8	58,49	10,36	N	0,44	N	0,76	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3914	3914	G	T	MI.12018	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	608	203	G	V	gGg/gTg	8,95	1	0	probably_damaging	1	neutral	0,5	neutral	2,46	deleterious	-3,11	deleterious	-8,56	high_impact	4,19	damaging	0,54	damaging	0,1	deleterious	3,88	23,5	0,04	0,35	disease	0,52	disease	0,87	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,28	high_impact	2,47	0,1	0,8	58,49	10,36	P	0,59	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3916	3916	G	A	MI.12019	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	610	204	E	K	Gag/Aag	-5,52	0	0	probably_damaging	1	neutral	0,87	neutral	1,77	deleterious	-4,61	deleterious	-3,81	high_impact	4,46	damaging	0,52	damaging	0,05	deleterious	4,59	24,4	0,06	0,35	neutral	0,49	disease	0,9	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,74	high_impact	2,71	0,5	0,8	59,75	10,56	N	0,43	N	0,99	polymorphism	1	0,25	rs878952713	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9091	9091	A	T	MI.1202	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	565	189	T	S	Aca/Tca	-5,66	0	0,01	benign	0,12	neutral	0,92	neutral	4,49	neutral	-0,28	neutral	0,07	neutral_impact	-0,78	neutral	0,88	neutral	0,96	deleterious	0,16	4,21	0,54	0,65	neutral	0,44	neutral	0,14	neutral	0,29	neutral	0,28	4	neutral	0,04	deleterious	0,9	neutral	-6	neutral	0,19	medium_impact	0,07	medium_impact	0,89	low_impact	-1,77	0,72	0,9	29,2	23,91	N	0,29	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3916	3916	G	C	MI.12020	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	610	204	E	Q	Gag/Cag	-5,52	0	0	probably_damaging	1	neutral	0,58	neutral	1,75	deleterious	-5,04	deleterious	-2,86	high_impact	4,25	damaging	0,51	damaging	0,05	deleterious	3,53	23,1	0,12	0,4	disease	0,54	disease	0,8	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,35	high_impact	2,52	0,56	0,8	59,75	10,56	N	0,34	N	0,91	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3917	3917	A	T	MI.12021	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	611	204	E	V	gAg/gTg	7,11	1	0	probably_damaging	1	neutral	0,36	neutral	1,73	deleterious	-5,97	deleterious	-6,67	high_impact	4,8	damaging	0,57	damaging	0,06	deleterious	4,5	24,3	0,04	0,35	disease	0,74	disease	0,9	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,14	high_impact	3	0,23	0,8	59,75	10,56	P	0,72	P	0,83	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3917	3917	A	C	MI.12022	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	611	204	E	A	gAg/gCg	7,11	1	0	probably_damaging	1	neutral	0,78	neutral	1,75	deleterious	-4,91	deleterious	-5,72	high_impact	4,8	damaging	0,52	damaging	0,09	deleterious	3,95	23,6	0,05	0,35	disease	0,55	disease	0,81	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,58	high_impact	3	0,26	0,8	59,75	10,56	P	0,69	P	0,74	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3917	3917	A	G	MI.12023	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	611	204	E	G	gAg/gGg	7,11	1	0	probably_damaging	1	neutral	0,42	neutral	1,74	deleterious	-5,26	deleterious	-6,67	high_impact	4,46	damaging	0,48	damaging	0,08	deleterious	4,49	24,3	0,06	0,35	disease	0,63	disease	0,82	disease	0,71	disease	0,67	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	0,2	high_impact	2,71	0,12	0,8	59,75	10,56	P	0,59	P	0,61	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3918	3918	G	T	MI.12024	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	612	204	E	D	gaG/gaT	8,49	1	0	probably_damaging	1	neutral	0,63	neutral	1,8	deleterious	-3,99	deleterious	-2,86	high_impact	4	damaging	0,56	damaging	0,05	deleterious	3,95	23,6	0,11	0,4	neutral	0,38	disease	0,79	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,4	high_impact	2,31	0,54	0,8	59,75	10,56	P	0,56	P	0,9	polymorphism	0,98	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3918	3918	G	C	MI.12025	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	612	204	E	D	gaG/gaC	8,49	1	0	probably_damaging	1	neutral	0,63	neutral	1,8	deleterious	-3,99	deleterious	-2,86	high_impact	4	damaging	0,56	damaging	0,05	deleterious	3,81	23,4	0,11	0,4	neutral	0,38	disease	0,79	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,4	high_impact	2,31	0,54	0,8	59,75	10,56	P	0,55	P	0,9	polymorphism	0,98	0,24	rs28357972	Uncertain significance	not_specified	RCV000223701.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	3919	3919	T	C	MI.12026	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	613	205	S	P	Tcc/Ccc	-0,01	0,8	0	probably_damaging	1	neutral	0,36	neutral	2,58	deleterious	-3,31	deleterious	-4,76	high_impact	4,14	neutral	0,75	damaging	0,04	deleterious	4,16	23,8	0,08	0,35	disease	0,55	disease	0,8	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,14	high_impact	2,43	0,12	0,8	60,06	10,41	N	0,45	N	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	T3919C	LHON (putative)	+	-	Reported	1
chrM	3919	3919	T	A	MI.12027	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	613	205	S	T	Tcc/Acc	-0,01	0,8	0	probably_damaging	1	neutral	0,72	neutral	2,63	neutral	-1,25	deleterious	-2,86	medium_impact	3,31	neutral	0,63	damaging	0,05	deleterious	4,13	23,8	0,32	0,5	neutral	0,34	disease	0,68	disease	0,63	disease	0,64	3	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,51	medium_impact	1,7	0,48	0,8	60,06	10,41	N	0,3	N	0,68	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3919	3919	T	G	MI.12028	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	613	205	S	A	Tcc/Gcc	-0,01	0,8	0	probably_damaging	1	neutral	0,94	neutral	2,67	neutral	-1,57	deleterious	-2,86	medium_impact	2,77	neutral	0,65	damaging	0,11	deleterious	3,83	23,4	0,29	0,45	neutral	0,21	disease	0,54	disease	0,6	neutral	0,33	3	deleterious	1	deleterious	0,47	deleterious	1	deleterious	0,67	low_impact	-3,57	medium_impact	0,94	medium_impact	1,23	0,3	0,8	60,06	10,41	N	0,27	N	0,46	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3920	3920	C	T	MI.12029	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	614	205	S	F	tCc/tTc	7,34	1	0	probably_damaging	1	neutral	0,56	neutral	2,57	deleterious	-4,88	deleterious	-5,71	high_impact	4,69	neutral	0,68	damaging	0,02	deleterious	4,41	24,1	0,07	0,35	disease	0,64	disease	0,84	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,33	high_impact	2,91	0,04	0,8	60,06	10,41	P	0,64	P	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9092	9092	C	A	MI.1203	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	566	189	T	K	aCa/aAa	0,82	0,36	0	benign	0,19	neutral	0,13	neutral	4,41	neutral	-1,73	neutral	-2	low_impact	1,86	neutral	0,86	neutral	0,51	deleterious	2,68	20,7	0,2	0,65	disease	0,5	disease	0,74	disease	0,68	disease	0,75	5	neutral	0,85	deleterious	0,47	neutral	-6	neutral	0,36	medium_impact	-0,16	medium_impact	-0,18	medium_impact	0,5	0,74	0,9	29,2	23,91	N	0,28	N	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3920	3920	C	A	MI.12030	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	614	205	S	Y	tCc/tAc	7,34	1	0	probably_damaging	1	neutral	0,73	neutral	2,57	deleterious	-4,47	deleterious	-5,71	high_impact	4,69	neutral	0,7	damaging	0,04	deleterious	4,14	23,8	0,07	0,35	disease	0,6	disease	0,83	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,52	high_impact	2,91	0,16	0,8	60,06	10,41	P	0,64	P	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3920	3920	C	G	MI.12031	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	614	205	S	C	tCc/tGc	7,34	1	0	probably_damaging	1	neutral	0,16	neutral	2,56	deleterious	-5,85	deleterious	-4,76	high_impact	4,69	neutral	0,71	damaging	0,03	deleterious	3,67	23,3	0,07	0,35	disease	0,77	disease	0,76	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	-0,13	high_impact	2,91	0,24	0,8	60,06	10,41	P	0,69	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3922	3922	G	A	MI.12032	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	616	206	E	K	Gaa/Aaa	-10,12	0	0	probably_damaging	1	neutral	0,71	neutral	2,19	deleterious	-6,47	deleterious	-3,79	high_impact	4,11	damaging	0,54	damaging	0,06	deleterious	4,59	24,4	0,04	0,35	disease	0,71	disease	0,89	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	0,49	high_impact	2,4	0,75	0,85	59,75	10,58	N	0,41	N	0,99	polymorphism	1	0,47	.	.	.	.	.	head/neck tumor	.	.	.	.	.	.	.	.	.
chrM	3922	3922	G	C	MI.12033	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	616	206	E	Q	Gaa/Caa	-10,12	0	0	probably_damaging	1	neutral	0,47	neutral	2,17	deleterious	-6,55	deleterious	-2,85	high_impact	4,8	damaging	0,53	damaging	0,07	deleterious	3,5	23,1	0,09	0,4	disease	0,72	disease	0,79	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,25	high_impact	3	0,48	0,8	59,75	10,58	P	0,6	P	0,91	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3923	3923	A	G	MI.12034	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	617	206	E	G	gAa/gGa	5,96	1	0	probably_damaging	1	neutral	0,39	neutral	2,15	deleterious	-6,54	deleterious	-6,64	high_impact	4,46	damaging	0,5	damaging	0,1	deleterious	4,46	24,2	0,03	0,35	disease	0,74	disease	0,81	disease	0,71	disease	0,68	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,17	high_impact	2,71	0,12	0,8	59,75	10,58	P	0,61	P	0,61	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3923	3923	A	T	MI.12035	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	617	206	E	V	gAa/gTa	5,96	1	0	probably_damaging	1	neutral	0,3	neutral	2,13	deleterious	-8,26	deleterious	-6,64	high_impact	4,46	damaging	0,59	damaging	0,07	deleterious	4,41	24,2	0,02	0,35	disease	0,88	disease	0,9	disease	0,72	disease	0,62	2	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	0,07	high_impact	2,71	0,23	0,8	59,75	10,58	P	0,63	P	0,83	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3923	3923	A	C	MI.12036	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	617	206	E	A	gAa/gCa	5,96	1	0	probably_damaging	1	neutral	0,65	neutral	2,17	deleterious	-6,66	deleterious	-5,68	high_impact	4,8	damaging	0,53	damaging	0,11	deleterious	3,78	23,4	0,03	0,35	disease	0,73	disease	0,8	disease	0,71	disease	0,68	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,43	high_impact	3	0,27	0,8	59,75	10,58	P	0,69	P	0,74	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3924	3924	A	T	MI.12037	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	618	206	E	D	gaA/gaT	6,65	1	0	probably_damaging	1	neutral	0,56	neutral	2,24	deleterious	-4,38	deleterious	-2,85	high_impact	3,7	damaging	0,58	damaging	0,07	deleterious	3,89	23,5	0,07	0,35	neutral	0,47	disease	0,79	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,33	high_impact	2,04	0,43	0,8	59,75	10,58	P	0,59	P	0,9	polymorphism	0,98	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3924	3924	A	C	MI.12038	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	618	206	E	D	gaA/gaC	6,65	1	0	probably_damaging	1	neutral	0,56	neutral	2,24	deleterious	-4,38	deleterious	-2,85	high_impact	3,7	damaging	0,58	damaging	0,07	deleterious	3,78	23,4	0,07	0,35	neutral	0,47	disease	0,79	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,33	high_impact	2,04	0,43	0,8	59,75	10,58	P	0,59	P	0,9	polymorphism	0,98	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3925	3925	C	G	MI.12039	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	619	207	L	V	Cta/Gta	0,91	0,43	0	probably_damaging	1	neutral	0,28	neutral	2,33	deleterious	-3,42	deleterious	-2,85	high_impact	3,87	damaging	0,59	damaging	0,05	deleterious	3,52	23,1	0,12	0,4	neutral	0,49	disease	0,66	disease	0,51	disease	0,53	1	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,05	high_impact	2,19	0,4	0,8	59,75	10,53	N	0,34	N	0,84	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9092	9092	C	T	MI.1204	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	566	189	T	M	aCa/aTa	0,82	0,36	0	possibly_damaging	0,78	neutral	0,22	neutral	4,35	neutral	-1,98	neutral	-1,66	neutral_impact	0,7	neutral	0,9	neutral	0,63	deleterious	3,89	23,5	0,35	0,65	neutral	0,5	neutral	0,45	neutral	0,36	neutral	0,31	4	neutral	0,86	neutral	0,22	neutral	-3	deleterious	0,55	low_impact	-1,28	medium_impact	-0,02	medium_impact	-0,5	0,88	0,9	29,2	23,91	N	0,38	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3925	3925	C	A	MI.12040	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	619	207	L	M	Cta/Ata	0,91	0,43	0	probably_damaging	1	neutral	0,1	neutral	2,24	deleterious	-4,69	neutral	-1,9	high_impact	4,76	damaging	0,59	damaging	0,06	deleterious	4,03	23,6	0,11	0,4	disease	0,64	disease	0,6	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	-0,26	high_impact	2,97	0,55	0,8	59,75	10,53	P	0,65	P	0,89	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3926	3926	T	A	MI.12041	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	620	207	L	Q	cTa/cAa	-0,47	0,2	0	probably_damaging	1	neutral	0,55	neutral	2,22	deleterious	-7,88	deleterious	-5,71	high_impact	4,76	damaging	0,48	damaging	0,05	deleterious	4,53	24,3	0,01	0,35	disease	0,87	disease	0,82	disease	0,64	disease	0,63	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,32	high_impact	2,97	0,24	0,8	59,75	10,53	P	0,59	P	0,99	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3926	3926	T	G	MI.12042	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	620	207	L	R	cTa/cGa	-0,47	0,2	0	probably_damaging	1	neutral	0,49	neutral	2,22	deleterious	-7,96	deleterious	-5,71	high_impact	4,76	damaging	0,5	damaging	0,04	deleterious	4,36	24,1	0,01	0,35	disease	0,87	disease	0,87	disease	0,75	disease	0,65	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,27	high_impact	2,97	0,12	0,8	59,75	10,53	P	0,64	P	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3926	3926	T	C	MI.12043	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	620	207	L	P	cTa/cCa	-0,47	0,2	0	probably_damaging	1	neutral	0,26	neutral	2,21	deleterious	-8,26	deleterious	-6,66	high_impact	4,76	damaging	0,46	damaging	0,04	deleterious	4,11	23,7	0,01	0,35	disease	0,9	disease	0,82	disease	0,75	disease	0,64	3	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,02	high_impact	2,97	0,11	0,8	59,75	10,53	P	0,6	P	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3928	3928	G	A	MI.12044	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	622	208	V	I	Gtc/Atc	-1,39	0	0	benign	0,22	neutral	0,41	neutral	2,32	neutral	-2,02	neutral	-0,95	medium_impact	3,17	neutral	0,65	damaging	0,1	deleterious	3,72	23,3	0,43	0,55	neutral	0,34	disease	0,67	disease	0,56	disease	0,63	3	neutral	0,5	deleterious	0,6	neutral	-3	neutral	0,26	medium_impact	-0,24	medium_impact	0,19	medium_impact	1,58	0,77	0,85	59,43	10,43	N	0,32	N	0,39	polymorphism	1	0,06	.	.	.	.	.	.	COSM1138364	.	.	.	.	.	.	.	.
chrM	3928	3928	G	T	MI.12045	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	622	208	V	F	Gtc/Ttc	-1,39	0	0	probably_damaging	0,97	neutral	0,72	neutral	2,18	deleterious	-3,88	deleterious	-4,76	high_impact	4,41	damaging	0,56	damaging	0,04	deleterious	3,97	23,6	0,04	0,35	disease	0,54	disease	0,92	disease	0,69	disease	0,69	4	neutral	0,96	neutral	0,38	deleterious	2	deleterious	0,83	low_impact	-2,17	medium_impact	0,51	high_impact	2,66	0,39	0,8	59,43	10,43	N	0,37	N	0,99	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3928	3928	G	C	MI.12046	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	622	208	V	L	Gtc/Ctc	-1,39	0	0	possibly_damaging	0,68	neutral	0,74	neutral	2,27	neutral	-2,48	deleterious	-2,85	high_impact	4,75	damaging	0,6	damaging	0,04	deleterious	3,67	23,3	0,15	0,45	neutral	0,34	disease	0,8	disease	0,63	disease	0,65	3	neutral	0,62	deleterious	0,53	deleterious	1	deleterious	0,57	low_impact	-1,06	medium_impact	0,53	high_impact	2,96	0,43	0,8	59,43	10,43	P	0,57	P	0,71	disease_causing_automatic	0	0,28	rs587776442	Pathogenic	Leigh_syndrome	RCV000144023.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	3929	3929	T	G	MI.12047	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	623	208	V	G	gTc/gGc	7,11	1	0	probably_damaging	0,98	neutral	0,45	neutral	2,15	deleterious	-5,09	deleterious	-6,67	high_impact	3,86	damaging	0,58	damaging	0,07	deleterious	3,93	23,5	0,02	0,35	disease	0,58	disease	0,85	disease	0,68	disease	0,68	4	deleterious	0,98	neutral	0,24	deleterious	2	deleterious	0,81	low_impact	-2,34	medium_impact	0,23	high_impact	2,18	0,18	0,8	59,43	10,43	P	0,55	P	0,95	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3929	3929	T	C	MI.12048	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	623	208	V	A	gTc/gCc	7,11	1	0	possibly_damaging	0,86	neutral	0,61	neutral	2,24	neutral	-2,84	deleterious	-3,81	high_impact	3,66	damaging	0,53	damaging	0,09	deleterious	3,72	23,3	0,14	0,4	neutral	0,32	disease	0,71	disease	0,58	disease	0,63	3	neutral	0,83	neutral	0,38	deleterious	1	deleterious	0,71	low_impact	-1,49	medium_impact	0,38	high_impact	2,01	0,21	0,8	59,43	10,43	P	0,58	P	0,64	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3929	3929	T	A	MI.12049	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	623	208	V	D	gTc/gAc	7,11	1	0	probably_damaging	0,99	neutral	0,29	neutral	2,14	deleterious	-5,72	deleterious	-6,67	high_impact	4,75	neutral	0,63	damaging	0,05	deleterious	4,8	24,8	0,02	0,35	disease	0,57	disease	0,91	disease	0,77	disease	0,7	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-2,62	medium_impact	0,06	high_impact	2,96	0,14	0,8	59,43	10,43	P	0,73	P	0,99	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9094	9094	C	T	MI.1205	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	568	190	L	F	Ctt/Ttt	-16,07	0	0	possibly_damaging	0,81	neutral	0,52	neutral	4,17	neutral	-1,99	neutral	-1,62	low_impact	0,94	neutral	0,95	neutral	0,92	deleterious	2,54	19,72	0,41	0,65	neutral	0,23	neutral	0,27	neutral	0,34	neutral	0,42	2	neutral	0,79	neutral	0,36	neutral	-3	deleterious	0,61	low_impact	-1,35	medium_impact	0,31	medium_impact	-0,29	0,78	0,9	18,58	14,09	N	0,37	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3931	3931	T	A	MI.12050	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	625	209	S	T	Tca/Aca	-8,97	0	0	probably_damaging	1	neutral	0,44	neutral	2,69	neutral	-1,34	deleterious	-2,86	high_impact	3,81	neutral	0,62	damaging	0,06	deleterious	3,85	23,4	0,21	0,45	neutral	0,25	disease	0,73	disease	0,6	disease	0,64	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,74	low_impact	-3,57	medium_impact	0,22	high_impact	2,14	0,42	0,8	59,12	10,49	N	0,33	N	0,68	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3931	3931	T	G	MI.12051	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	625	209	S	A	Tca/Gca	-8,97	0	0	probably_damaging	1	neutral	0,55	neutral	2,84	neutral	0,97	deleterious	-2,86	medium_impact	2,19	neutral	0,6	damaging	0,1	deleterious	3,78	23,4	0,28	0,45	neutral	0,16	disease	0,59	neutral	0,45	neutral	0,15	7	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,32	medium_impact	0,72	0,31	0,8	59,12	10,49	N	0,23	N	0,46	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3931	3931	T	C	MI.12052	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	625	209	S	P	Tca/Cca	-8,97	0	0	probably_damaging	1	neutral	0,22	neutral	2,64	deleterious	-3,01	deleterious	-4,76	high_impact	4,27	neutral	0,7	damaging	0,03	deleterious	4,09	23,7	0,07	0,35	disease	0,52	disease	0,84	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	-0,03	high_impact	2,54	0,13	0,8	59,12	10,49	N	0,36	N	0,99	polymorphism	1	0,34	.	.	.	.	.	head/neck tumor	.	.	.	.	.	.	.	.	.
chrM	3932	3932	C	G	MI.12053	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	626	209	S	W	tCa/tGa	7,34	1	0	probably_damaging	1	neutral	0,18	neutral	2,61	deleterious	-3,79	deleterious	-6,66	high_impact	4,62	neutral	0,7	damaging	0,03	deleterious	4,49	24,3	0,05	0,35	disease	0,82	disease	0,89	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	-0,09	high_impact	2,85	0,15	0,8	59,12	10,49	P	0,65	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3932	3932	C	T	MI.12054	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	626	209	S	L	tCa/tTa	7,34	1	0	probably_damaging	1	neutral	0,71	neutral	2,66	neutral	-2,12	deleterious	-5,71	high_impact	4,27	neutral	0,61	damaging	0,02	deleterious	4,79	24,7	0,07	0,35	neutral	0,38	disease	0,87	disease	0,58	disease	0,67	3	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,49	high_impact	2,54	0,48	0,8	59,12	10,49	P	0,54	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3934	3934	G	T	MI.12055	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	628	210	G	C	Ggc/Tgc	-8,97	0	0	probably_damaging	1	neutral	0,18	neutral	1,08	deleterious	-8,86	deleterious	-8,53	high_impact	4,82	damaging	0,44	damaging	0,03	deleterious	4,28	24	0,02	0,35	disease	0,87	disease	0,89	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	-0,09	high_impact	3,02	0,18	0,8	59,43	10,34	P	0,5	N	0,98	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3934	3934	G	C	MI.12056	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	628	210	G	R	Ggc/Cgc	-8,97	0	0	probably_damaging	1	neutral	0,4	neutral	1,09	deleterious	-7,75	deleterious	-7,57	high_impact	4,82	damaging	0,48	damaging	0,04	deleterious	4,12	23,8	0,02	0,35	disease	0,87	disease	0,87	disease	0,85	disease	0,72	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,92	low_impact	-3,57	medium_impact	0,18	high_impact	3,02	0,43	0,8	59,43	10,34	P	0,58	P	0,99	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3934	3934	G	A	MI.12057	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	628	210	G	S	Ggc/Agc	-8,97	0	0	probably_damaging	1	neutral	0,55	neutral	1,12	deleterious	-5,9	deleterious	-5,68	high_impact	4,47	damaging	0,25	damaging	0,06	deleterious	4,31	24	0,02	0,35	disease	0,59	disease	0,86	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,32	high_impact	2,72	0,33	0,8	59,43	10,34	P	0,67	P	0,99	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3935	3935	G	C	MI.12058	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	629	210	G	A	gGc/gCc	7,11	1	0	probably_damaging	1	neutral	0,6	neutral	1,13	deleterious	-5,66	deleterious	-5,68	high_impact	4,82	damaging	0,31	damaging	0,07	deleterious	3,23	22,8	0,02	0,35	neutral	0,36	disease	0,75	disease	0,76	disease	0,7	4	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,37	high_impact	3,02	0,29	0,8	59,43	10,34	P	0,77	P	0,76	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3935	3935	G	A	MI.12059	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	629	210	G	D	gGc/gAc	7,11	1	0	probably_damaging	1	neutral	0,29	neutral	1,1	deleterious	-6,71	deleterious	-6,63	high_impact	4,82	damaging	0,43	damaging	0,04	deleterious	3,99	23,6	0,02	0,35	disease	0,83	disease	0,89	disease	0,84	disease	0,74	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	0,06	high_impact	3,02	0,15	0,8	59,43	10,34	P	0,79	P	1	polymorphism	1	0,47	.	.	.	.	.	.	COSM1155623	.	.	.	.	.	.	.	.
chrM	9094	9094	C	G	MI.1206	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	568	190	L	V	Ctt/Gtt	-16,07	0	0	benign	0,32	neutral	0,43	neutral	4,23	neutral	-1,24	neutral	-0,52	low_impact	1,57	neutral	0,87	neutral	0,8	deleterious	0,69	8,74	0,44	0,65	neutral	0,47	neutral	0,22	neutral	0,34	neutral	0,36	3	neutral	0,49	deleterious	0,56	neutral	-6	neutral	0,34	medium_impact	-0,45	medium_impact	0,22	medium_impact	0,25	0,75	0,9	18,58	14,09	N	0,38	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3935	3935	G	T	MI.12060	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	629	210	G	V	gGc/gTc	7,11	1	0	probably_damaging	1	neutral	0,56	neutral	1,09	deleterious	-7,4	deleterious	-8,52	high_impact	4,82	damaging	0,39	damaging	0,05	deleterious	3,89	23,5	0,02	0,35	disease	0,79	disease	0,89	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	0,33	high_impact	3,02	0,15	0,8	59,43	10,34	P	0,74	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3937	3937	T	G	MI.12061	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	631	211	F	V	Ttc/Gtc	-8,51	0	0	probably_damaging	1	neutral	0,65	neutral	2,44	neutral	-2,86	deleterious	-6,57	high_impact	3,6	neutral	0,62	damaging	0,16	deleterious	4,27	23,9	0,05	0,35	neutral	0,24	disease	0,87	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	0,43	medium_impact	1,96	0,33	0,8	58,81	10,12	N	0,35	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3937	3937	T	A	MI.12062	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	631	211	F	I	Ttc/Atc	-8,51	0	0	probably_damaging	1	neutral	0,48	neutral	2,43	deleterious	-3,04	deleterious	-5,63	high_impact	4,22	neutral	0,72	damaging	0,18	deleterious	4,57	24,4	0,13	0,4	neutral	0,27	disease	0,83	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,26	high_impact	2,5	0,46	0,8	58,81	10,12	N	0,43	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3937	3937	T	C	MI.12063	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	631	211	F	L	Ttc/Ctc	-8,51	0	0	probably_damaging	1	neutral	0,81	neutral	2,48	neutral	-2,23	deleterious	-5,63	high_impact	3,6	neutral	0,74	damaging	0,15	deleterious	4,24	23,9	0,19	0,45	neutral	0,2	disease	0,79	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,41	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	0,63	medium_impact	1,96	0,7	0,85	58,81	10,12	N	0,37	N	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3938	3938	T	A	MI.12064	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	632	211	F	Y	tTc/tAc	7,34	1	0	probably_damaging	1	neutral	1	neutral	2,85	neutral	0,16	deleterious	-2,79	low_impact	1,72	neutral	0,77	damaging	0,18	deleterious	4,36	24,1	0,18	0,45	neutral	0,18	disease	0,71	neutral	0,35	neutral	0,2	6	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,74	low_impact	-3,57	high_impact	1,96	medium_impact	0,31	0,63	0,8	58,81	10,12	N	0,47	N	0,88	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3938	3938	T	G	MI.12065	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	632	211	F	C	tTc/tGc	7,34	1	0	probably_damaging	1	neutral	0,2	neutral	2,38	deleterious	-5,34	deleterious	-7,52	high_impact	4,57	neutral	0,7	damaging	0,15	deleterious	4,25	23,9	0,03	0,35	disease	0,6	disease	0,87	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	-0,06	high_impact	2,8	0,13	0,8	58,81	10,12	P	0,63	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3938	3938	T	C	MI.12066	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	632	211	F	S	tTc/tCc	7,34	1	0	probably_damaging	1	neutral	0,8	neutral	2,41	deleterious	-3,68	deleterious	-7,5	high_impact	4,57	neutral	0,69	damaging	0,19	deleterious	4,39	24,1	0,02	0,35	neutral	0,39	disease	0,88	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,4	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,61	high_impact	2,8	0,22	0,8	58,81	10,12	P	0,56	P	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3939	3939	C	G	MI.12067	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	633	211	F	L	ttC/ttG	4,58	1	0	probably_damaging	1	neutral	0,81	neutral	2,48	neutral	-2,23	deleterious	-5,63	high_impact	3,6	neutral	0,74	damaging	0,15	deleterious	4,49	24,3	0,19	0,45	neutral	0,2	disease	0,79	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,41	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	0,63	medium_impact	1,96	0,7	0,85	58,81	10,12	N	0,48	N	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3939	3939	C	A	MI.12068	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	633	211	F	L	ttC/ttA	4,58	1	0	probably_damaging	1	neutral	0,81	neutral	2,48	neutral	-2,23	deleterious	-5,63	high_impact	3,6	neutral	0,74	damaging	0,15	deleterious	4,81	24,8	0,19	0,45	neutral	0,2	disease	0,79	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,41	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	0,63	medium_impact	1,96	0,7	0,85	58,81	10,12	N	0,5	N	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3940	3940	A	C	MI.12069	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	634	212	N	H	Aac/Cac	-3,92	0	0	probably_damaging	1	neutral	0,54	neutral	2,63	neutral	0,99	deleterious	-4,75	medium_impact	2,46	neutral	0,65	damaging	0,08	deleterious	3,2	22,7	0,29	0,45	neutral	0,32	disease	0,79	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,78	low_impact	-3,57	medium_impact	0,31	medium_impact	0,96	0,18	0,8	60,38	10,35	N	0,23	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9094	9094	C	A	MI.1207	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	568	190	L	I	Ctt/Att	-16,07	0	0	benign	0,43	neutral	0,98	neutral	4,4	neutral	0,04	neutral	-0,44	neutral_impact	0,2	neutral	0,87	neutral	0,9	deleterious	0,54	7,77	0,44	0,65	neutral	0,34	neutral	0,08	neutral	0,25	neutral	0,28	4	neutral	0,4	deleterious	0,78	neutral	-6	neutral	0,43	medium_impact	-0,64	medium_impact	1,25	medium_impact	-0,93	0,73	0,9	18,58	14,09	N	0,38	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3940	3940	A	T	MI.12070	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	634	212	N	Y	Aac/Tac	-3,92	0	0	probably_damaging	1	neutral	1	neutral	2,6	neutral	-0,81	deleterious	-7,61	high_impact	3,93	neutral	0,66	damaging	0,07	deleterious	3,83	23,4	0,07	0,35	neutral	0,41	disease	0,89	disease	0,69	disease	0,71	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,82	low_impact	-3,57	high_impact	1,96	high_impact	2,24	0,12	0,8	60,38	10,35	N	0,29	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3940	3940	A	G	MI.12071	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	634	212	N	D	Aac/Gac	-3,92	0	0	probably_damaging	1	neutral	0,21	neutral	2,65	neutral	-1,66	deleterious	-4,75	high_impact	4,62	neutral	0,78	damaging	0,13	deleterious	3,93	23,5	0,34	0,5	neutral	0,4	disease	0,79	disease	0,68	disease	0,67	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	-0,05	high_impact	2,85	0,21	0,8	60,38	10,35	N	0,51	P	0,97	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3941	3941	A	G	MI.12072	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	635	212	N	S	aAc/aGc	6,65	1	0	probably_damaging	1	neutral	0,42	neutral	2,67	neutral	-0,37	deleterious	-4,75	high_impact	3,73	neutral	0,65	damaging	0,1	deleterious	3,22	22,7	0,31	0,45	neutral	0,27	disease	0,82	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,2	high_impact	2,07	0,21	0,8	60,38	10,35	P	0,59	P	0,9	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3941	3941	A	C	MI.12073	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	635	212	N	T	aAc/aCc	6,65	1	0	probably_damaging	1	neutral	0,39	neutral	2,65	neutral	-0,03	deleterious	-5,71	high_impact	3,93	neutral	0,62	damaging	0,1	deleterious	3,51	23,1	0,2	0,45	neutral	0,29	disease	0,84	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,17	high_impact	2,24	0,24	0,8	60,38	10,35	P	0,58	P	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3941	3941	A	T	MI.12074	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	635	212	N	I	aAc/aTc	6,65	1	0	probably_damaging	1	neutral	0,4	neutral	2,61	neutral	0,16	deleterious	-8,56	high_impact	3,82	neutral	0,71	damaging	0,11	deleterious	4,14	23,8	0,1	0,4	neutral	0,22	disease	0,91	disease	0,58	disease	0,68	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,18	high_impact	2,15	0,1	0,8	60,38	10,35	P	0,54	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3942	3942	C	A	MI.12075	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	636	212	N	K	aaC/aaA	5,5	1	0	probably_damaging	1	neutral	0,29	neutral	2,71	neutral	-0,71	deleterious	-5,71	high_impact	4,28	neutral	0,63	damaging	0,07	deleterious	4,6	24,4	0,22	0,45	neutral	0,29	disease	0,84	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,06	high_impact	2,55	0,27	0,8	60,38	10,35	P	0,62	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3942	3942	C	G	MI.12076	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	636	212	N	K	aaC/aaG	5,5	1	0	probably_damaging	1	neutral	0,29	neutral	2,71	neutral	-0,71	deleterious	-5,71	high_impact	4,28	neutral	0,63	damaging	0,07	deleterious	4,07	23,7	0,22	0,45	neutral	0,29	disease	0,84	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,06	high_impact	2,55	0,27	0,8	60,38	10,35	P	0,62	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3943	3943	A	G	MI.12077	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	637	213	I	V	Atc/Gtc	-3	0	0	benign	0	neutral	0,6	neutral	3,05	neutral	1,16	neutral	0,82	neutral_impact	-1,54	neutral	0,6	neutral	0,77	neutral	-1,54	0	0,48	0,55	neutral	0,19	neutral	0,05	neutral	0,2	neutral	0,22	6	neutral	0,39	deleterious	0,8	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,37	low_impact	-2,53	0,54	0,8	24,21	37,99	N	0,42	N	0,04	polymorphism	1	0,01	rs879176055	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3943	3943	A	T	MI.12078	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	637	213	I	F	Atc/Ttc	-3	0	0	benign	0,36	neutral	0,75	neutral	2,57	neutral	-1,69	deleterious	-3,79	medium_impact	2,88	neutral	0,69	neutral	0,55	deleterious	1,86	15,37	0,07	0,35	neutral	0,38	disease	0,76	neutral	0,5	disease	0,56	1	neutral	0,25	deleterious	0,7	neutral	-3	neutral	0,42	medium_impact	-0,52	medium_impact	0,54	medium_impact	1,33	0,63	0,8	24,21	37,99	N	0,28	N	0,66	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3943	3943	A	C	MI.12079	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	637	213	I	L	Atc/Ctc	-3	0	0	benign	0,04	neutral	0,71	neutral	2,7	neutral	0,18	neutral	-1,89	medium_impact	2,08	neutral	0,69	neutral	0,53	deleterious	1,87	15,42	0,24	0,45	neutral	0,14	disease	0,52	disease	0,57	disease	0,67	3	neutral	0,23	deleterious	0,84	neutral	-3	neutral	0,16	medium_impact	0,55	medium_impact	0,49	medium_impact	0,63	0,74	0,85	24,21	37,99	N	0,31	N	0,52	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9095	9095	T	A	MI.1208	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	569	190	L	H	cTt/cAt	-7,51	0	0,01	possibly_damaging	0,9	neutral	0,16	neutral	4,11	deleterious	-4,15	deleterious	-2,63	medium_impact	3,38	neutral	0,8	neutral	0,48	deleterious	4,17	23,8	0,17	0,65	disease	0,88	disease	0,53	disease	0,59	disease	0,68	4	neutral	0,95	neutral	0,13	NA	0	deleterious	0,76	low_impact	-1,66	medium_impact	-0,12	medium_impact	1,8	0,68	0,9	18,58	14,09	N	0,34	N	0,84	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3944	3944	T	A	MI.12080	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	638	213	I	N	aTc/aAc	4,81	1	0	benign	0,32	neutral	0,33	neutral	2,55	neutral	-2,68	deleterious	-5,73	medium_impact	2,88	neutral	0,68	neutral	0,55	deleterious	2,68	20,7	0,04	0,35	disease	0,54	disease	0,86	disease	0,6	disease	0,76	5	neutral	0,6	deleterious	0,51	neutral	-3	deleterious	0,44	medium_impact	-0,44	medium_impact	0,1	medium_impact	1,33	0,19	0,8	24,21	37,99	P	0,58	P	0,85	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3944	3944	T	C	MI.12081	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	638	213	I	T	aTc/aCc	4,81	1	0	benign	0	neutral	0,4	neutral	2,69	neutral	2,25	deleterious	-2,94	neutral_impact	0,34	neutral	0,64	neutral	0,67	neutral	1,62	13,94	0,06	0,35	neutral	0,13	neutral	0,5	neutral	0,4	neutral	0,21	6	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,15	high_impact	2,07	medium_impact	0,18	medium_impact	-0,89	0,31	0,8	24,21	37,99	N	0,47	N	0,08	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3944	3944	T	G	MI.12082	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	638	213	I	S	aTc/aGc	4,81	1	0	benign	0,15	neutral	0,47	neutral	2,57	neutral	-1,2	deleterious	-4,79	medium_impact	2,19	neutral	0,69	neutral	0,55	deleterious	2,51	19,56	0,02	0,35	neutral	0,28	disease	0,76	disease	0,63	disease	0,7	4	neutral	0,44	deleterious	0,66	neutral	-3	neutral	0,26	medium_impact	-0,04	medium_impact	0,25	medium_impact	0,72	0,22	0,8	24,21	37,99	N	0,55	P	0,7	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3945	3945	C	G	MI.12083	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	639	213	I	M	atC/atG	4,58	1	0	possibly_damaging	0,56	neutral	0,22	neutral	2,58	neutral	-1,66	neutral	-1,95	medium_impact	2,88	neutral	0,6	neutral	0,48	neutral	1,65	14,15	0,14	0,4	neutral	0,37	disease	0,53	disease	0,62	disease	0,68	4	neutral	0,77	neutral	0,33	NA	0	neutral	0,39	medium_impact	-0,85	medium_impact	-0,03	medium_impact	1,33	0,7	0,85	24,21	37,99	P	0,66	P	0,65	polymorphism	0,97	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3945	3945	C	A	MI.12084	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	639	213	I	M	atC/atA	4,58	1	0	possibly_damaging	0,56	neutral	0,22	neutral	2,58	neutral	-1,66	neutral	-1,95	medium_impact	2,88	neutral	0,6	neutral	0,48	deleterious	2,12	17	0,14	0,4	neutral	0,37	disease	0,53	disease	0,62	disease	0,68	4	neutral	0,77	neutral	0,33	NA	0	neutral	0,39	medium_impact	-0,85	medium_impact	-0,03	medium_impact	1,33	0,7	0,85	24,21	37,99	P	0,66	P	0,65	polymorphism	0,97	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3946	3946	G	C	MI.12085	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	640	214	E	Q	Gaa/Caa	-1,85	0	0	probably_damaging	1	neutral	0,29	neutral	2,14	deleterious	-6,82	deleterious	-2,84	high_impact	4,46	neutral	0,67	neutral	0,5	deleterious	3,45	23	0,05	0,35	disease	0,85	disease	0,85	disease	0,81	disease	0,67	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,06	high_impact	2,71	0,54	0,8	59,75	10,47	P	0,62	P	0,91	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3946	3946	G	A	MI.12086	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	640	214	E	K	Gaa/Aaa	-1,85	0	0	probably_damaging	1	neutral	0,29	neutral	2,16	deleterious	-6,66	deleterious	-3,79	high_impact	4,25	neutral	0,62	neutral	0,39	deleterious	4,63	24,5	0,02	0,35	disease	0,82	disease	0,93	disease	0,81	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	0,06	high_impact	2,52	0,68	0,85	59,75	10,47	P	0,66	P	0,99	disease_causing_automatic	0	0,46	rs199476123	Pathogenic	Juvenile_myopathy,_encephalopathy,_lactic_acidosis_AND_stroke	RCV000010387.3	MedGen:OMIM:Orphanet:SNOMED_CT	.	COSM1138366	.	.	G3946A	MELAS	+	+	Reported	5
chrM	3947	3947	A	T	MI.12087	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	641	214	E	V	gAa/gTa	8,95	1	0	probably_damaging	1	neutral	0,52	neutral	2,1	deleterious	-8,19	deleterious	-6,64	high_impact	4,8	neutral	0,63	neutral	0,42	deleterious	4,39	24,1	0,01	0,35	disease	0,92	disease	0,93	disease	0,81	disease	0,64	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,9	low_impact	-3,57	medium_impact	0,29	high_impact	3	0,28	0,8	59,75	10,47	P	0,74	P	0,83	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3947	3947	A	G	MI.12088	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	641	214	E	G	gAa/gGa	8,95	1	0	probably_damaging	1	neutral	0,35	neutral	2,12	deleterious	-7,06	deleterious	-6,64	high_impact	4,8	neutral	0,7	neutral	0,57	deleterious	4,4	24,1	0,02	0,35	disease	0,84	disease	0,86	disease	0,8	disease	0,67	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,12	high_impact	3	0,09	0,8	59,75	10,47	P	0,76	P	0,61	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3947	3947	A	C	MI.12089	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	641	214	E	A	gAa/gCa	8,95	1	0	probably_damaging	1	neutral	0,51	neutral	2,14	deleterious	-6,89	deleterious	-5,69	high_impact	4,8	neutral	0,69	neutral	0,51	deleterious	3,89	23,5	0,02	0,35	disease	0,84	disease	0,83	disease	0,79	disease	0,67	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	0,29	high_impact	3	0,32	0,8	59,75	10,47	P	0,76	P	0,74	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9095	9095	T	C	MI.1209	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	569	190	L	P	cTt/cCt	-7,51	0	0,01	benign	0	neutral	0,06	neutral	4,13	deleterious	-3,22	neutral	-1,63	low_impact	1,18	neutral	0,96	neutral	0,72	neutral	0,97	10,52	0,14	0,65	disease	0,88	disease	0,71	disease	0,64	disease	0,74	5	neutral	0,94	deleterious	0,53	neutral	-6	neutral	0,32	high_impact	2,09	medium_impact	-0,38	medium_impact	-0,09	0,66	0,9	18,58	14,09	N	0,34	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	COSM1138414	.	.	.	.	.	.	.	.
chrM	3948	3948	A	T	MI.12090	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	642	214	E	D	gaA/gaT	8,49	1	0	probably_damaging	1	neutral	0,2	neutral	2,21	deleterious	-4,9	deleterious	-2,85	high_impact	3,77	neutral	0,75	neutral	0,5	deleterious	3,88	23,5	0,07	0,35	disease	0,71	disease	0,84	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,06	high_impact	2,1	0,62	0,8	59,75	10,47	P	0,71	P	0,9	polymorphism	0,98	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3948	3948	A	C	MI.12091	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	642	214	E	D	gaA/gaC	8,49	1	0	probably_damaging	1	neutral	0,2	neutral	2,21	deleterious	-4,9	deleterious	-2,85	high_impact	3,77	neutral	0,75	neutral	0,5	deleterious	3,78	23,4	0,07	0,35	disease	0,71	disease	0,84	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,06	high_impact	2,1	0,62	0,8	59,75	10,47	P	0,7	P	0,9	polymorphism	0,98	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3949	3949	T	A	MI.12092	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	643	215	Y	N	Tac/Aac	-0,01	0,92	0	probably_damaging	1	neutral	0,31	neutral	2,02	deleterious	-7,87	deleterious	-8,52	high_impact	4,72	neutral	0,68	neutral	0,39	deleterious	4,35	24,1	0,02	0,35	disease	0,66	disease	0,91	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,08	high_impact	2,93	0,14	0,8	59,75	10,42	P	0,61	P	1	polymorphism	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3949	3949	T	C	MI.12093	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	643	215	Y	H	Tac/Cac	-0,01	0,92	0	probably_damaging	1	neutral	0,54	neutral	2,03	deleterious	-5,18	deleterious	-4,74	medium_impact	3,48	damaging	0,58	neutral	0,3	deleterious	3,75	23,3	0,05	0,35	disease	0,59	disease	0,86	disease	0,82	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,84	low_impact	-3,57	medium_impact	0,31	medium_impact	1,85	0,2	0,8	59,75	10,42	P	0,54	P	1	disease_causing_automatic	0	0,23	rs199476124	Pathogenic	Juvenile_myopathy,_encephalopathy,_lactic_acidosis_AND_stroke	RCV000010388.2	MedGen:OMIM:Orphanet:SNOMED_CT	thyroid oncocytoma	.	.	.	T3949C	MELAS	-	+	Reported	5
chrM	3949	3949	T	G	MI.12094	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	643	215	Y	D	Tac/Gac	-0,01	0,92	0	probably_damaging	1	neutral	0,2	neutral	2,01	deleterious	-8,79	deleterious	-9,47	high_impact	4,72	neutral	0,71	neutral	0,35	deleterious	4,11	23,8	0,02	0,35	disease	0,72	disease	0,91	disease	0,81	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,06	high_impact	2,93	0,11	0,8	59,75	10,42	P	0,63	P	1	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3950	3950	A	G	MI.12095	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	644	215	Y	C	tAc/tGc	7,34	1	0	probably_damaging	1	neutral	0,17	neutral	2,01	deleterious	-8,8	deleterious	-8,53	high_impact	4,38	neutral	0,72	damaging	0,28	deleterious	3,58	23,2	0,02	0,35	disease	0,78	disease	0,91	disease	0,79	disease	0,66	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	-0,11	high_impact	2,64	0,15	0,8	59,75	10,42	P	0,65	P	1	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3950	3950	A	C	MI.12096	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	644	215	Y	S	tAc/tCc	7,34	1	0	probably_damaging	1	neutral	0,42	neutral	2,03	deleterious	-7,27	deleterious	-8,52	high_impact	4,72	neutral	0,65	neutral	0,46	deleterious	3,75	23,3	0,03	0,35	disease	0,54	disease	0,9	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,2	high_impact	2,93	0,16	0,8	59,75	10,42	P	0,67	P	1	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3950	3950	A	T	MI.12097	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	644	215	Y	F	tAc/tTc	7,34	1	0	probably_damaging	1	neutral	0,71	neutral	2,2	deleterious	-3,96	deleterious	-3,79	medium_impact	2,4	neutral	0,63	neutral	0,42	deleterious	3,42	23	0,1	0,4	neutral	0,41	disease	0,84	disease	0,66	neutral	0,33	3	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,81	low_impact	-3,57	medium_impact	0,49	medium_impact	0,91	0,33	0,8	59,75	10,42	N	0,53	P	0,8	polymorphism	0,99	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3952	3952	G	C	MI.12098	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	646	216	A	P	Gcc/Ccc	-5,98	0	0	probably_damaging	0,98	neutral	0,2	neutral	2,52	neutral	-2,53	deleterious	-4,64	high_impact	3,53	neutral	0,72	neutral	0,36	deleterious	3,99	23,6	0,03	0,35	disease	0,64	disease	0,94	disease	0,59	disease	0,73	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-2,34	medium_impact	-0,06	medium_impact	1,89	0,46	0,8	54,4	8,49	N	0,36	N	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3952	3952	G	T	MI.12099	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	646	216	A	S	Gcc/Tcc	-5,98	0	0	benign	0,33	neutral	0,43	neutral	2,97	neutral	2,88	deleterious	-2,62	neutral_impact	0,36	neutral	0,73	neutral	0,61	deleterious	3,76	23,3	0,16	0,45	neutral	0,15	neutral	0,39	neutral	0,23	neutral	0,42	2	neutral	0,49	deleterious	0,55	neutral	-6	neutral	0,33	medium_impact	-0,46	medium_impact	0,21	medium_impact	-0,87	0,29	0,8	54,4	8,49	N	0,37	N	0,93	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8582	8582	C	T	MI.121	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	56	19	A	V	gCc/gTc	-0,57	0	0	probably_damaging	1	deleterious	0,04	neutral	4,73	neutral	0,47	neutral	1,01	neutral_impact	-0,24	neutral	0,95	neutral	0,93	deleterious	3,11	22,5	0,33	0,65	neutral	0,26	disease	0,55	neutral	0,39	neutral	0,48	0	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,7	low_impact	-3,6	medium_impact	-0,49	low_impact	-1,3	0,58	0,9	29,65	29,28	N	0,44	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9095	9095	T	G	MI.1210	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	569	190	L	R	cTt/cGt	-7,51	0	0,01	possibly_damaging	0,8	neutral	0,11	neutral	4,12	deleterious	-3,57	neutral	-2,13	medium_impact	3,03	neutral	0,78	neutral	0,42	deleterious	4,06	23,7	0,11	0,65	disease	0,84	disease	0,71	disease	0,7	disease	0,77	5	neutral	0,93	neutral	0,16	NA	0	deleterious	0,76	low_impact	-1,33	medium_impact	-0,22	medium_impact	1,5	0,74	0,9	18,58	14,09	N	0,29	N	0,8	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3952	3952	G	A	MI.12100	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	646	216	A	T	Gcc/Acc	-5,98	0	0	probably_damaging	0,91	neutral	0,39	neutral	2,56	neutral	-0,58	deleterious	-3,65	medium_impact	2,6	neutral	0,65	neutral	0,47	deleterious	4,44	24,2	0,13	0,4	neutral	0,22	disease	0,84	neutral	0,29	neutral	0,45	1	neutral	0,91	neutral	0,24	deleterious	1	deleterious	0,69	low_impact	-1,69	medium_impact	0,17	medium_impact	1,08	0,56	0,8	54,4	8,49	N	0,38	N	0,7	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3953	3953	C	G	MI.12101	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	647	216	A	G	gCc/gGc	2,98	0,99	0	possibly_damaging	0,86	neutral	0,35	neutral	2,54	neutral	-0,12	deleterious	-3,67	low_impact	1,61	neutral	0,71	neutral	0,46	deleterious	4,13	23,8	0,15	0,4	neutral	0,27	disease	0,8	neutral	0,26	neutral	0,19	6	neutral	0,87	neutral	0,25	neutral	-3	deleterious	0,67	low_impact	-1,49	medium_impact	0,12	medium_impact	0,22	0,5	0,8	54,4	8,49	N	0,51	P	0,79	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3953	3953	C	A	MI.12102	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	647	216	A	D	gCc/gAc	2,98	0,99	0	probably_damaging	0,96	neutral	0,2	neutral	2,51	neutral	-1,91	deleterious	-5,51	high_impact	3,88	neutral	0,74	neutral	0,32	deleterious	4,65	24,5	0,03	0,35	disease	0,66	disease	0,94	disease	0,71	disease	0,8	6	neutral	0,97	neutral	0,12	deleterious	2	deleterious	0,84	low_impact	-2,05	medium_impact	-0,06	high_impact	2,2	0,27	0,8	54,4	8,49	P	0,59	P	0,98	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3953	3953	C	T	MI.12103	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	647	216	A	V	gCc/gTc	2,98	0,99	0	probably_damaging	0,94	neutral	0,52	neutral	2,52	neutral	-1,44	deleterious	-3,77	high_impact	3,53	neutral	0,73	neutral	0,4	deleterious	4,64	24,5	0,07	0,35	disease	0,55	disease	0,9	disease	0,61	disease	0,7	4	neutral	0,93	neutral	0,29	deleterious	2	deleterious	0,78	low_impact	-1,87	medium_impact	0,29	medium_impact	1,89	0,5	0,8	54,4	8,49	N	0,52	P	0,72	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3955	3955	G	C	MI.12104	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	649	217	A	P	Gca/Cca	-4,38	0	0	probably_damaging	1	neutral	0,2	neutral	2,66	deleterious	-3,58	deleterious	-3,1	medium_impact	3,31	neutral	0,66	damaging	0,1	deleterious	4,03	23,6	0,04	0,35	disease	0,61	disease	0,94	disease	0,59	disease	0,79	6	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,88	low_impact	-3,57	medium_impact	-0,06	medium_impact	1,7	0,44	0,8	55,35	10,3	N	0,32	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3955	3955	G	T	MI.12105	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	649	217	A	S	Gca/Tca	-4,38	0	0	probably_damaging	1	neutral	0,41	neutral	2,9	neutral	0,7	neutral	-1,18	low_impact	1,04	neutral	0,81	damaging	0,18	deleterious	3,84	23,4	0,1	0,4	neutral	0,17	neutral	0,5	neutral	0,2	neutral	0,31	4	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,72	low_impact	-3,57	medium_impact	0,19	medium_impact	-0,28	0,4	0,8	55,35	10,3	N	0,32	N	0,93	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3955	3955	G	A	MI.12106	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	649	217	A	T	Gca/Aca	-4,38	0	0	probably_damaging	1	neutral	0,39	neutral	2,73	neutral	-2,14	deleterious	-2,68	high_impact	3,65	neutral	0,68	damaging	0,15	deleterious	4,36	24,1	0,06	0,35	neutral	0,4	disease	0,78	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,17	medium_impact	2	0,52	0,8	55,35	10,3	N	0,34	N	0,7	polymorphism	1	0,2	rs28552781	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3956	3956	C	G	MI.12107	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	650	217	A	G	gCa/gGa	5,04	0,99	0	probably_damaging	1	neutral	0,35	neutral	2,86	neutral	2,88	neutral	1,65	neutral_impact	-0,24	neutral	0,8	neutral	0,93	neutral	1,37	12,65	0,09	0,35	neutral	0,16	neutral	0,21	neutral	0,24	neutral	0,36	3	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,67	low_impact	-3,57	medium_impact	0,12	low_impact	-1,4	0,38	0,8	55,35	10,3	P	0,52	P	0,79	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3956	3956	C	T	MI.12108	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	650	217	A	V	gCa/gTa	5,04	0,99	0	probably_damaging	1	neutral	0,51	neutral	2,68	deleterious	-3	deleterious	-3,24	high_impact	3,65	neutral	0,69	damaging	0,13	deleterious	4,62	24,5	0,06	0,35	disease	0,52	disease	0,86	disease	0,61	disease	0,74	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,29	medium_impact	2	0,44	0,8	55,35	10,3	P	0,57	P	0,72	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3956	3956	C	A	MI.12109	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	650	217	A	E	gCa/gAa	5,04	0,99	0	probably_damaging	1	neutral	0,29	neutral	2,71	neutral	-2,82	deleterious	-3,09	medium_impact	3,31	neutral	0,7	damaging	0,1	deleterious	4,62	24,5	0,03	0,35	neutral	0,48	disease	0,91	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,84	low_impact	-3,57	medium_impact	0,06	medium_impact	1,7	0,27	0,8	55,35	10,3	P	0,57	P	0,96	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9097	9097	A	G	MI.1211	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	571	191	I	V	Atc/Gtc	-8,2	0	0	probably_damaging	0,93	neutral	0,19	neutral	4,47	neutral	0,18	neutral	-0,45	low_impact	0,88	neutral	0,9	neutral	0,94	deleterious	1,92	15,69	0,58	0,7	neutral	0,32	neutral	0,19	neutral	0,35	neutral	0,37	3	neutral	0,96	neutral	0,13	neutral	-2	deleterious	0,6	low_impact	-1,82	medium_impact	-0,06	medium_impact	-0,34	0,54	0,9	19,47	23,84	N	0,48	N	0,61	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3958	3958	G	A	MI.12110	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	652	218	G	S	Ggc/Agc	-2,77	0	0	probably_damaging	1	neutral	0,41	neutral	2,74	neutral	0,25	deleterious	-5,61	medium_impact	2,5	damaging	0,33	damaging	0,03	deleterious	4,3	24	0,14	0,4	neutral	0,18	disease	0,85	neutral	0,49	neutral	0,47	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-3,57	medium_impact	0,19	medium_impact	1	0,74	0,85	60,38	10,42	P	0,52	P	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	G3958A	LHON (putative)	+	-	Reported	1
chrM	3958	3958	G	T	MI.12111	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	652	218	G	C	Ggc/Tgc	-2,77	0	0	probably_damaging	1	neutral	0,17	neutral	2,69	neutral	-2,03	deleterious	-8,49	high_impact	4,25	damaging	0,46	damaging	0,01	deleterious	4,29	24	0,06	0,35	disease	0,51	disease	0,93	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	-0,11	high_impact	2,52	0,17	0,8	60,38	10,42	N	0,42	N	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3958	3958	G	C	MI.12112	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	652	218	G	R	Ggc/Cgc	-2,77	0	0	probably_damaging	1	neutral	0,34	neutral	2,72	neutral	0,4	deleterious	-7,55	high_impact	4,25	damaging	0,47	damaging	0,02	deleterious	4,11	23,7	0,06	0,35	neutral	0,37	disease	0,93	disease	0,7	disease	0,77	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,11	high_impact	2,52	0,57	0,8	60,38	10,42	N	0,43	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3959	3959	G	A	MI.12113	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	653	218	G	D	gGc/gAc	5,96	1	0	probably_damaging	1	neutral	0,2	neutral	2,7	neutral	-1,56	deleterious	-6,59	high_impact	4,25	damaging	0,45	damaging	0,02	deleterious	4,04	23,7	0,04	0,35	neutral	0,47	disease	0,91	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	-0,06	high_impact	2,52	0,17	0,8	60,38	10,42	P	0,72	P	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	G3959A	MELAS	.	.	Reported	1
chrM	3959	3959	G	C	MI.12114	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	653	218	G	A	gGc/gCc	5,96	1	0	probably_damaging	1	neutral	0,5	neutral	2,77	neutral	0,42	deleterious	-5,64	medium_impact	2,9	damaging	0,38	damaging	0,05	deleterious	3,26	22,8	0,18	0,45	neutral	0,18	disease	0,72	neutral	0,48	neutral	0,22	6	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	0,28	medium_impact	1,34	0,33	0,8	60,38	10,42	P	0,61	P	0,76	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3959	3959	G	T	MI.12115	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	653	218	G	V	gGc/gTc	5,96	1	0	probably_damaging	1	neutral	0,52	neutral	2,84	neutral	1,01	deleterious	-8,5	medium_impact	2,32	damaging	0,42	damaging	0,02	deleterious	3,9	23,5	0,09	0,35	neutral	0,15	disease	0,91	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,29	medium_impact	0,84	0,15	0,8	60,38	10,42	N	0,49	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3961	3961	C	A	MI.12116	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	655	219	P	T	Ccc/Acc	-20	0	0	possibly_damaging	0,64	neutral	0,38	neutral	2,74	neutral	0	deleterious	-7,2	medium_impact	2,69	neutral	0,67	neutral	0,36	deleterious	3,79	23,4	0,13	0,4	neutral	0,2	disease	0,84	neutral	0,3	neutral	0,49	0	neutral	0,68	neutral	0,37	NA	0	deleterious	0,56	medium_impact	-0,99	medium_impact	0,16	medium_impact	1,16	0,59	0,8	50,31	10,14	N	0,37	N	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3961	3961	C	G	MI.12117	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	655	219	P	A	Ccc/Gcc	-20	0	0	benign	0,39	neutral	0,5	neutral	2,81	neutral	0,6	deleterious	-7,2	medium_impact	2,31	neutral	0,74	neutral	0,44	deleterious	3,16	22,6	0,15	0,4	neutral	0,15	disease	0,71	neutral	0,45	neutral	0,37	3	neutral	0,44	deleterious	0,56	neutral	-3	neutral	0,41	medium_impact	-0,57	medium_impact	0,28	medium_impact	0,83	0,61	0,8	50,31	10,14	N	0,32	N	0,78	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3961	3961	C	T	MI.12118	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	655	219	P	S	Ccc/Tcc	-20	0	0	benign	0,08	neutral	0,41	neutral	2,76	neutral	0,5	deleterious	-7,11	low_impact	1,7	neutral	0,72	neutral	0,66	deleterious	3,98	23,6	0,18	0,45	neutral	0,17	disease	0,78	neutral	0,28	neutral	0,21	6	neutral	0,54	deleterious	0,67	neutral	-6	neutral	0,21	medium_impact	0,25	medium_impact	0,19	medium_impact	0,3	0,2	0,8	50,31	10,14	N	0,44	N	0,74	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3962	3962	C	G	MI.12119	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	656	219	P	R	cCc/cGc	7,11	1	0	probably_damaging	0,9	neutral	0,34	neutral	2,74	neutral	1,07	deleterious	-8,15	medium_impact	1,96	neutral	0,72	neutral	0,36	deleterious	3,77	23,4	0,09	0,35	neutral	0,12	disease	0,94	disease	0,62	disease	0,75	5	neutral	0,91	neutral	0,22	deleterious	1	deleterious	0,72	low_impact	-1,65	medium_impact	0,11	medium_impact	0,52	0,38	0,8	50,31	10,14	N	0,48	N	0,71	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9097	9097	A	C	MI.1212	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	571	191	I	L	Atc/Ctc	-8,2	0	0	probably_damaging	0,93	neutral	1	neutral	4,53	neutral	0,1	neutral	-0,29	neutral_impact	-0,52	neutral	0,83	neutral	0,87	neutral	1,16	11,52	0,34	0,65	neutral	0,33	neutral	0,12	neutral	0,23	neutral	0,28	4	neutral	0,93	deleterious	0,54	neutral	-2	deleterious	0,59	low_impact	-1,82	high_impact	1,98	low_impact	-1,54	0,62	0,9	19,47	23,84	N	0,25	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3962	3962	C	A	MI.12120	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	656	219	P	H	cCc/cAc	7,11	1	0	probably_damaging	0,96	neutral	0,53	neutral	2,69	neutral	-0,8	deleterious	-8,14	medium_impact	3,12	neutral	0,72	neutral	0,3	deleterious	4,2	23,9	0,08	0,35	neutral	0,28	disease	0,87	neutral	0,42	disease	0,66	3	neutral	0,96	neutral	0,29	deleterious	1	deleterious	0,74	low_impact	-2,05	medium_impact	0,3	medium_impact	1,54	0,33	0,8	50,31	10,14	N	0,5	N	0,69	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3962	3962	C	T	MI.12121	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	656	219	P	L	cCc/cTc	7,11	1	0	possibly_damaging	0,81	neutral	0,65	neutral	2,71	neutral	0,14	deleterious	-9,12	medium_impact	2,14	neutral	0,72	neutral	0,38	deleterious	4,57	24,4	0,13	0,4	neutral	0,27	disease	0,91	neutral	0,44	neutral	0,49	0	neutral	0,78	neutral	0,42	NA	0	deleterious	0,7	low_impact	-1,34	medium_impact	0,43	medium_impact	0,68	0,64	0,8	50,31	10,14	N	0,48	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3964	3964	T	G	MI.12122	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	658	220	F	V	Ttc/Gtc	-8,05	0	0	probably_damaging	1	neutral	0,51	neutral	2,25	deleterious	-3,39	deleterious	-6,64	high_impact	4,41	neutral	0,64	neutral	0,51	deleterious	4,29	24	0,05	0,35	neutral	0,43	disease	0,88	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,29	high_impact	2,66	0,28	0,8	59,75	10,29	N	0,48	N	0,98	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3964	3964	T	A	MI.12123	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	658	220	F	I	Ttc/Atc	-8,05	0	0	probably_damaging	1	neutral	0,39	neutral	2,24	deleterious	-3,59	deleterious	-5,69	high_impact	4,21	neutral	0,71	neutral	0,6	deleterious	4,55	24,3	0,09	0,35	neutral	0,47	disease	0,87	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,17	high_impact	2,49	0,42	0,8	59,75	10,29	N	0,51	P	0,97	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3964	3964	T	C	MI.12124	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	658	220	F	L	Ttc/Ctc	-8,05	0	0	probably_damaging	1	neutral	0,65	neutral	2,3	neutral	-2,58	deleterious	-5,68	high_impact	3,72	neutral	0,62	neutral	0,56	deleterious	4,2	23,9	0,12	0,4	neutral	0,26	disease	0,85	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,72	low_impact	-3,57	medium_impact	0,43	high_impact	2,06	0,55	0,8	59,75	10,29	N	0,46	N	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3965	3965	T	C	MI.12125	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	659	220	F	S	tTc/tCc	7,34	1	0	probably_damaging	1	neutral	0,42	neutral	2,24	deleterious	-3,59	deleterious	-7,59	high_impact	4,41	neutral	0,72	neutral	0,66	deleterious	4,39	24,1	0,02	0,35	disease	0,51	disease	0,87	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,2	high_impact	2,66	0,23	0,8	59,75	10,29	P	0,7	P	0,98	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3965	3965	T	G	MI.12126	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	659	220	F	C	tTc/tGc	7,34	1	0	probably_damaging	1	neutral	0,17	neutral	2,19	deleterious	-5,89	deleterious	-7,59	high_impact	4,76	neutral	0,7	neutral	0,49	deleterious	4,26	23,9	0,02	0,35	disease	0,78	disease	0,88	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	-0,11	high_impact	2,97	0,2	0,8	59,75	10,29	P	0,7	P	1	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3965	3965	T	A	MI.12127	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	659	220	F	Y	tTc/tAc	7,34	1	0	probably_damaging	1	neutral	1	neutral	2,42	neutral	-1,56	deleterious	-2,85	medium_impact	3,38	neutral	0,7	neutral	0,46	deleterious	4,39	24,1	0,12	0,4	neutral	0,4	disease	0,82	disease	0,68	disease	0,68	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,77	low_impact	-3,57	high_impact	1,96	medium_impact	1,76	0,55	0,8	59,75	10,29	P	0,55	P	0,88	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3966	3966	C	G	MI.12128	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	660	220	F	L	ttC/ttG	5,73	1	0	probably_damaging	1	neutral	0,65	neutral	2,3	neutral	-2,58	deleterious	-5,68	high_impact	3,72	neutral	0,62	neutral	0,56	deleterious	4,46	24,2	0,12	0,4	neutral	0,26	disease	0,85	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,72	low_impact	-3,57	medium_impact	0,43	high_impact	2,06	0,55	0,8	59,75	10,29	P	0,57	P	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3966	3966	C	A	MI.12129	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	660	220	F	L	ttC/ttA	5,73	1	0	probably_damaging	1	neutral	0,65	neutral	2,3	neutral	-2,58	deleterious	-5,68	high_impact	3,72	neutral	0,62	neutral	0,56	deleterious	4,79	24,7	0,12	0,4	neutral	0,26	disease	0,85	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,72	low_impact	-3,57	medium_impact	0,43	high_impact	2,06	0,55	0,8	59,75	10,29	P	0,57	P	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9097	9097	A	T	MI.1213	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	571	191	I	F	Atc/Ttc	-8,2	0	0	probably_damaging	0,99	neutral	0,37	neutral	4,37	neutral	-1,73	neutral	-2,46	low_impact	1,17	neutral	0,86	neutral	0,49	deleterious	3,79	23,4	0,32	0,65	neutral	0,43	disease	0,55	neutral	0,36	neutral	0,48	0	deleterious	0,99	neutral	0,19	neutral	-2	deleterious	0,71	low_impact	-2,65	medium_impact	0,16	medium_impact	-0,1	0,71	0,9	19,47	23,84	N	0,27	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3967	3967	G	T	MI.12130	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	661	221	A	S	Gcc/Tcc	-2,77	0	0	probably_damaging	1	neutral	0,46	neutral	2,53	neutral	-2,82	deleterious	-2,79	medium_impact	2,94	neutral	0,74	damaging	0,09	deleterious	3,85	23,4	0,12	0,4	neutral	0,49	disease	0,87	disease	0,51	disease	0,68	4	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,83	low_impact	-3,57	medium_impact	0,24	medium_impact	1,38	0,37	0,8	59,12	10,43	N	0,26	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3967	3967	G	C	MI.12131	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	661	221	A	P	Gcc/Ccc	-2,77	0	0	probably_damaging	1	neutral	0,19	neutral	2,46	deleterious	-4,81	deleterious	-4,69	high_impact	4	neutral	0,71	damaging	0,07	deleterious	3,96	23,6	0,02	0,35	disease	0,74	disease	0,9	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,08	high_impact	2,31	0,4	0,8	59,12	10,43	N	0,37	N	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3967	3967	G	A	MI.12132	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	661	221	A	T	Gcc/Acc	-2,77	0	0	probably_damaging	1	neutral	0,35	neutral	2,53	deleterious	-3,02	deleterious	-3,66	medium_impact	2,64	neutral	0,77	damaging	0,13	deleterious	4,37	24,1	0,09	0,35	disease	0,53	disease	0,87	disease	0,51	neutral	0,39	2	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,83	low_impact	-3,57	medium_impact	0,12	medium_impact	1,12	0,71	0,85	59,12	10,43	N	0,33	N	0,7	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3968	3968	C	A	MI.12133	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	662	221	A	D	gCc/gAc	5,04	1	0	probably_damaging	1	neutral	0,18	neutral	2,47	deleterious	-3,9	deleterious	-5,63	high_impact	4,54	neutral	0,8	damaging	0,09	deleterious	4,66	24,5	0,02	0,35	disease	0,74	disease	0,93	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	-0,09	high_impact	2,78	0,27	0,8	59,12	10,43	P	0,64	P	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3968	3968	C	G	MI.12134	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	662	221	A	G	gCc/gGc	5,04	1	0	probably_damaging	1	neutral	0,45	neutral	2,52	neutral	-0,8	deleterious	-3,77	medium_impact	2,48	neutral	0,76	damaging	0,11	deleterious	4,15	23,8	0,13	0,4	neutral	0,26	disease	0,84	disease	0,57	disease	0,68	4	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	0,23	medium_impact	0,98	0,58	0,8	59,12	10,43	N	0,48	N	0,79	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3968	3968	C	T	MI.12135	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	662	221	A	V	gCc/gTc	5,04	1	0	probably_damaging	1	neutral	0,48	neutral	2,57	neutral	-2,27	deleterious	-3,73	medium_impact	2,58	neutral	0,76	damaging	0,12	deleterious	4,63	24,5	0,05	0,35	neutral	0,4	disease	0,87	disease	0,55	disease	0,58	2	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,8	low_impact	-3,57	medium_impact	0,26	medium_impact	1,07	0,62	0,8	59,12	10,43	N	0,5	N	0,72	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3970	3970	C	A	MI.12136	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	664	222	L	M	Cta/Ata	-3,69	0	0,15	probably_damaging	1	neutral	0,22	neutral	1,92	deleterious	-3,65	neutral	-1,74	low_impact	1,65	neutral	0,85	neutral	0,84	deleterious	2,78	21,3	0,18	0,45	neutral	0,47	disease	0,51	neutral	0,27	neutral	0,38	2	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,71	low_impact	-3,57	medium_impact	-0,03	medium_impact	0,25	0,51	0,8	42,45	12,47	N	0,41	N	0,27	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3970	3970	C	G	MI.12137	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	664	222	L	V	Cta/Gta	-3,69	0	0,15	probably_damaging	1	neutral	0,49	neutral	1,93	deleterious	-3,52	deleterious	-2,79	medium_impact	2,9	neutral	0,67	damaging	0,15	deleterious	3,52	23,1	0,16	0,45	neutral	0,45	disease	0,7	disease	0,59	disease	0,65	3	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,27	medium_impact	1,34	0,51	0,8	42,45	12,47	N	0,24	N	0,69	polymorphism	1	0,11	rs9629042	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3971	3971	T	C	MI.12138	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	665	222	L	P	cTa/cCa	-0,7	0	0	probably_damaging	1	neutral	0,2	neutral	1,82	deleterious	-7,07	deleterious	-6,55	medium_impact	3,5	neutral	0,76	damaging	0,15	deleterious	4,02	23,6	0,02	0,35	disease	0,9	disease	0,85	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,87	low_impact	-3,57	medium_impact	-0,06	medium_impact	1,87	0,28	0,8	42,45	12,47	N	0,29	N	0,92	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3971	3971	T	A	MI.12139	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	665	222	L	Q	cTa/cAa	-0,7	0	0	probably_damaging	1	neutral	0,29	neutral	1,82	deleterious	-6,39	deleterious	-5,57	high_impact	4,12	neutral	0,72	damaging	0,14	deleterious	4,17	23,8	0,03	0,35	disease	0,87	disease	0,82	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,06	high_impact	2,41	0,35	0,8	42,45	12,47	N	0,36	N	0,94	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9098	9098	T	G	MI.1214	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	572	191	I	S	aTc/aGc	-1,26	0	0	probably_damaging	0,99	neutral	0,1	neutral	4,28	neutral	-1,48	deleterious	-2,99	medium_impact	1,94	neutral	0,89	neutral	0,49	deleterious	4,31	24	0,23	0,65	disease	0,71	disease	0,59	disease	0,58	disease	0,57	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,76	low_impact	-2,65	medium_impact	-0,25	medium_impact	0,57	0,68	0,9	19,47	23,84	N	0,43	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3971	3971	T	G	MI.12140	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	665	222	L	R	cTa/cGa	-0,7	0	0	probably_damaging	1	neutral	0,34	neutral	1,82	deleterious	-6,45	deleterious	-5,6	high_impact	4,47	neutral	0,74	damaging	0,12	deleterious	4,3	24	0,02	0,35	disease	0,87	disease	0,92	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,91	low_impact	-3,57	medium_impact	0,11	high_impact	2,72	0,21	0,8	42,45	12,47	N	0,44	N	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3973	3973	T	A	MI.12141	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	667	223	F	I	Ttc/Atc	-2,31	0	0	benign	0,24	neutral	0,4	neutral	2,62	neutral	-1,89	deleterious	-5,3	medium_impact	2	neutral	0,72	neutral	0,6	deleterious	2,57	19,9	0,14	0,4	neutral	0,28	disease	0,63	neutral	0,3	neutral	0,42	2	neutral	0,52	deleterious	0,58	neutral	-3	neutral	0,3	medium_impact	-0,28	medium_impact	0,18	medium_impact	0,56	0,42	0,8	59,43	10,3	N	0,38	N	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3973	3973	T	G	MI.12142	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	667	223	F	V	Ttc/Gtc	-2,31	0	0	benign	0,35	neutral	0,49	neutral	2,59	neutral	-2,1	deleterious	-6,22	medium_impact	3,33	neutral	0,66	neutral	0,5	deleterious	2,23	17,71	0,08	0,35	neutral	0,29	disease	0,9	disease	0,62	disease	0,72	4	neutral	0,43	deleterious	0,57	neutral	-3	neutral	0,35	medium_impact	-0,5	medium_impact	0,27	medium_impact	1,72	0,33	0,8	59,43	10,3	N	0,36	N	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3973	3973	T	C	MI.12143	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	667	223	F	L	Ttc/Ctc	-2,31	0	0	benign	0,02	neutral	0,65	neutral	2,71	neutral	-1,55	deleterious	-5,24	low_impact	1,5	neutral	0,68	neutral	0,58	deleterious	2,16	17,27	0,16	0,45	neutral	0,2	disease	0,78	neutral	0,34	neutral	0,5	0	neutral	0,32	deleterious	0,82	neutral	-6	neutral	0,17	medium_impact	0,84	medium_impact	0,43	medium_impact	0,12	0,48	0,8	59,43	10,3	N	0,32	N	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3974	3974	T	G	MI.12144	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	668	223	F	C	tTc/tGc	5,73	1	0	probably_damaging	0,92	neutral	0,17	neutral	2,46	deleterious	-5,1	deleterious	-7,18	high_impact	4,43	neutral	0,71	neutral	0,49	deleterious	3,78	23,4	0,03	0,35	disease	0,66	disease	0,91	disease	0,65	disease	0,73	5	neutral	0,96	neutral	0,13	deleterious	2	deleterious	0,77	low_impact	-1,75	medium_impact	-0,11	high_impact	2,68	0,27	0,8	59,43	10,3	P	0,67	P	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3974	3974	T	C	MI.12145	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	668	223	F	S	tTc/tCc	5,73	1	0	possibly_damaging	0,74	neutral	0,43	neutral	2,51	deleterious	-3,58	deleterious	-7,2	high_impact	4,08	neutral	0,7	neutral	0,62	deleterious	2,57	19,89	0,02	0,35	neutral	0,46	disease	0,88	disease	0,63	disease	0,71	4	neutral	0,74	neutral	0,35	deleterious	1	deleterious	0,66	low_impact	-1,18	medium_impact	0,21	high_impact	2,38	0,37	0,8	59,43	10,3	P	0,69	P	0,98	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3974	3974	T	A	MI.12146	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	668	223	F	Y	tTc/tAc	5,73	1	0	possibly_damaging	0,59	neutral	1	neutral	2,5	neutral	-2,95	deleterious	-2,71	medium_impact	3,27	neutral	0,72	neutral	0,46	deleterious	2,68	20,7	0,16	0,45	neutral	0,38	disease	0,84	disease	0,64	disease	0,7	4	neutral	0,59	deleterious	0,71	NA	0	deleterious	0,52	medium_impact	-0,9	high_impact	1,96	medium_impact	1,67	0,53	0,8	59,43	10,3	N	0,56	P	0,88	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3975	3975	C	G	MI.12147	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	669	223	F	L	ttC/ttG	7,34	1	0	benign	0,02	neutral	0,65	neutral	2,71	neutral	-1,55	deleterious	-5,24	low_impact	1,5	neutral	0,68	neutral	0,58	deleterious	2,51	19,53	0,16	0,45	neutral	0,2	disease	0,78	neutral	0,34	neutral	0,5	0	neutral	0,32	deleterious	0,82	neutral	-6	neutral	0,17	medium_impact	0,84	medium_impact	0,43	medium_impact	0,12	0,48	0,8	59,43	10,3	P	0,53	P	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3975	3975	C	A	MI.12148	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	669	223	F	L	ttC/ttA	7,34	1	0	benign	0,02	neutral	0,65	neutral	2,71	neutral	-1,55	deleterious	-5,24	low_impact	1,5	neutral	0,68	neutral	0,58	deleterious	2,79	21,3	0,16	0,45	neutral	0,2	disease	0,78	neutral	0,34	neutral	0,5	0	neutral	0,32	deleterious	0,82	neutral	-6	neutral	0,17	medium_impact	0,84	medium_impact	0,43	medium_impact	0,12	0,48	0,8	59,43	10,3	P	0,53	P	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3976	3976	T	G	MI.12149	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	670	224	F	V	Ttc/Gtc	-4,84	0	0	probably_damaging	1	neutral	0,5	neutral	2,47	neutral	-2,31	deleterious	-6,31	high_impact	4,19	neutral	0,63	damaging	0,13	deleterious	4,12	23,8	0,06	0,35	neutral	0,3	disease	0,9	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,74	low_impact	-3,57	medium_impact	0,28	high_impact	2,47	0,26	0,8	59,43	10,39	N	0,36	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9098	9098	T	C	MI.1215	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	572	191	I	T	aTc/aCc	-1,26	0	0	probably_damaging	0,99	neutral	0,07	neutral	4,3	neutral	-2,03	neutral	-1,86	low_impact	1,4	neutral	0,89	neutral	0,92	deleterious	2,36	18,53	0,39	0,65	disease	0,65	neutral	0,32	neutral	0,39	disease	0,62	2	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,72	low_impact	-2,65	medium_impact	-0,34	medium_impact	0,1	0,66	0,9	19,47	23,84	N	0,54	P	1	polymorphism	1	0,03	rs201559119	.	.	.	.	.	.	.	.	T9098C	Predisposition to anti-retroviral mitodisease	+	-	Reported	1
chrM	3976	3976	T	C	MI.12150	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	670	224	F	L	Ttc/Ctc	-4,84	0	0	probably_damaging	1	neutral	0,67	neutral	2,5	neutral	-1,86	deleterious	-5,41	high_impact	3,54	neutral	0,65	damaging	0,13	deleterious	4,07	23,7	0,11	0,4	neutral	0,25	disease	0,85	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,72	low_impact	-3,57	medium_impact	0,45	medium_impact	1,9	0,6	0,8	59,43	10,39	N	0,37	N	0,92	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3976	3976	T	A	MI.12151	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	670	224	F	I	Ttc/Atc	-4,84	0	0	probably_damaging	1	neutral	0,4	neutral	2,45	neutral	-2,53	deleterious	-5,41	high_impact	4,19	neutral	0,73	damaging	0,16	deleterious	4,42	24,2	0,14	0,4	neutral	0,35	disease	0,89	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,18	high_impact	2,47	0,5	0,8	59,43	10,39	N	0,45	N	0,97	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3977	3977	T	A	MI.12152	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	671	224	F	Y	tTc/tAc	5,73	1	0	probably_damaging	1	neutral	1	neutral	2,58	neutral	-1,17	deleterious	-2,7	medium_impact	3,46	neutral	0,7	damaging	0,13	deleterious	4,35	24,1	0,18	0,45	neutral	0,27	disease	0,82	disease	0,62	disease	0,68	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,74	low_impact	-3,57	high_impact	1,96	medium_impact	1,83	0,61	0,8	59,43	10,39	N	0,51	P	0,88	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3977	3977	T	G	MI.12153	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	671	224	F	C	tTc/tGc	5,73	1	0	probably_damaging	1	neutral	0,17	neutral	2,38	deleterious	-4,91	deleterious	-7,23	high_impact	4,74	neutral	0,7	damaging	0,13	deleterious	4,21	23,9	0,03	0,35	disease	0,66	disease	0,88	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	-0,11	high_impact	2,95	0,24	0,8	59,43	10,39	P	0,73	P	1	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3977	3977	T	C	MI.12154	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	671	224	F	S	tTc/tCc	5,73	1	0	probably_damaging	1	neutral	0,43	neutral	2,43	neutral	-2,96	deleterious	-7,17	high_impact	3,77	neutral	0,75	damaging	0,25	deleterious	4,36	24,1	0,02	0,35	neutral	0,23	disease	0,87	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	0,21	high_impact	2,1	0,31	0,8	59,43	10,39	P	0,59	P	0,98	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3978	3978	C	A	MI.12155	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	672	224	F	L	ttC/ttA	5,73	1	0	probably_damaging	1	neutral	0,67	neutral	2,5	neutral	-1,86	deleterious	-5,41	high_impact	3,54	neutral	0,65	damaging	0,13	deleterious	4,78	24,7	0,11	0,4	neutral	0,25	disease	0,85	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,72	low_impact	-3,57	medium_impact	0,45	medium_impact	1,9	0,6	0,8	59,43	10,39	N	0,53	P	0,92	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3978	3978	C	G	MI.12156	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	672	224	F	L	ttC/ttG	5,73	1	0	probably_damaging	1	neutral	0,67	neutral	2,5	neutral	-1,86	deleterious	-5,41	high_impact	3,54	neutral	0,65	damaging	0,13	deleterious	4,42	24,2	0,11	0,4	neutral	0,25	disease	0,85	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,72	low_impact	-3,57	medium_impact	0,45	medium_impact	1,9	0,6	0,8	59,43	10,39	N	0,53	P	0,92	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3979	3979	A	G	MI.12157	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	673	225	M	V	Ata/Gta	-3	0	0	probably_damaging	0,99	neutral	0,51	neutral	2,93	neutral	1,26	neutral	-1,32	low_impact	1,57	neutral	0,61	damaging	0,21	deleterious	2,72	20,9	0,19	0,45	neutral	0,18	disease	0,85	disease	0,51	disease	0,75	5	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,72	low_impact	-2,62	medium_impact	0,29	medium_impact	0,18	0,41	0,8	16,98	14,29	N	0,29	N	0,75	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3979	3979	A	T	MI.12158	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	673	225	M	L	Ata/Tta	-3	0	0	probably_damaging	0,98	neutral	0,77	neutral	3,27	neutral	2,83	neutral	1,19	neutral_impact	-1,39	neutral	0,8	neutral	0,95	deleterious	0,6	8,14	0,24	0,45	neutral	0,23	neutral	0,36	neutral	0,25	neutral	0,41	2	deleterious	0,98	neutral	0,4	neutral	-2	deleterious	0,62	low_impact	-2,34	medium_impact	0,57	low_impact	-2,4	0,39	0,8	16,98	14,29	N	0,26	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3979	3979	A	C	MI.12159	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	673	225	M	L	Ata/Cta	-3	0	0	probably_damaging	0,98	neutral	0,77	neutral	3,27	neutral	2,83	neutral	1,19	neutral_impact	-1,39	neutral	0,8	neutral	0,95	deleterious	0,53	7,67	0,24	0,45	neutral	0,23	neutral	0,36	neutral	0,25	neutral	0,41	2	deleterious	0,98	neutral	0,4	neutral	-2	deleterious	0,62	low_impact	-2,34	medium_impact	0,57	low_impact	-2,4	0,39	0,8	16,98	14,29	N	0,26	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9098	9098	T	A	MI.1216	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	572	191	I	N	aTc/aAc	-1,26	0	0	probably_damaging	1	deleterious	0,03	neutral	4,25	deleterious	-3,63	deleterious	-4,17	medium_impact	2,59	neutral	0,82	neutral	0,36	deleterious	4,43	24,2	0,21	0,65	disease	0,84	disease	0,64	disease	0,59	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-3,6	medium_impact	-0,56	medium_impact	1,12	0,63	0,9	19,47	23,84	N	0,32	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3980	3980	T	A	MI.12160	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	674	225	M	K	aTa/aAa	-0,47	0	0	probably_damaging	1	neutral	0,29	neutral	2,74	neutral	-1,8	deleterious	-3,98	medium_impact	3,08	neutral	0,62	damaging	0,17	deleterious	4,07	23,7	0,01	0,35	disease	0,6	disease	0,93	disease	0,69	disease	0,8	6	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,86	low_impact	-3,57	medium_impact	0,06	medium_impact	1,5	0,27	0,8	16,98	14,29	N	0,33	N	0,93	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3980	3980	T	C	MI.12161	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	674	225	M	T	aTa/aCa	-0,47	0	0	probably_damaging	1	neutral	0,39	neutral	2,77	neutral	-0,81	deleterious	-3,18	medium_impact	3,08	damaging	0,57	damaging	0,22	deleterious	3,07	22,4	0,07	0,35	neutral	0,4	disease	0,81	disease	0,61	disease	0,76	5	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-3,57	medium_impact	0,17	medium_impact	1,5	0,23	0,8	16,98	14,29	N	0,31	N	0,87	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3981	3981	A	T	MI.12162	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	675	225	M	I	atA/atT	7,34	0,99	0	probably_damaging	0,99	neutral	0,42	neutral	2,95	neutral	1,43	neutral	-0,53	neutral_impact	0,72	neutral	0,63	damaging	0,17	deleterious	3,55	23,1	0,25	0,45	neutral	0,16	disease	0,85	neutral	0,32	disease	0,51	0	deleterious	0,99	neutral	0,22	neutral	-2	deleterious	0,74	low_impact	-2,62	medium_impact	0,2	medium_impact	-0,56	0,5	0,8	16,98	14,29	P	0,5	N	0,74	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3981	3981	A	C	MI.12163	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	675	225	M	I	atA/atC	7,34	0,99	0	probably_damaging	0,99	neutral	0,42	neutral	2,95	neutral	1,43	neutral	-0,53	neutral_impact	0,72	neutral	0,63	damaging	0,17	deleterious	3,43	23	0,25	0,45	neutral	0,16	disease	0,85	neutral	0,32	disease	0,51	0	deleterious	0,99	neutral	0,22	neutral	-2	deleterious	0,74	low_impact	-2,62	medium_impact	0,2	medium_impact	-0,56	0,5	0,8	16,98	14,29	P	0,49	N	0,74	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3982	3982	G	T	MI.12164	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	676	226	A	S	Gcc/Tcc	-0,01	0,91	0	possibly_damaging	0,86	neutral	0,42	neutral	2,52	neutral	-1,66	deleterious	-2,68	medium_impact	1,96	neutral	0,7	damaging	0,12	deleterious	3,78	23,4	0,19	0,45	neutral	0,32	disease	0,8	neutral	0,3	neutral	0,46	1	neutral	0,85	neutral	0,28	NA	0	deleterious	0,74	low_impact	-1,49	medium_impact	0,2	medium_impact	0,52	0,47	0,8	59,75	10,37	N	0,3	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3982	3982	G	A	MI.12165	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	676	226	A	T	Gcc/Acc	-0,01	0,91	0	probably_damaging	0,95	neutral	0,31	neutral	2,46	neutral	-2,46	deleterious	-3,61	medium_impact	3,4	neutral	0,67	damaging	0,11	deleterious	4,34	24	0,11	0,4	neutral	0,43	disease	0,89	disease	0,58	disease	0,7	4	neutral	0,96	neutral	0,18	deleterious	1	deleterious	0,82	low_impact	-1,95	medium_impact	0,08	medium_impact	1,78	0,82	0,85	59,75	10,37	N	0,39	N	0,7	polymorphism	1	0,13	.	.	.	.	.	.	COSM1155625	.	.	.	.	.	.	.	.
chrM	3982	3982	G	C	MI.12166	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	676	226	A	P	Gcc/Ccc	-0,01	0,91	0	probably_damaging	0,99	neutral	0,23	neutral	2,4	deleterious	-3,97	deleterious	-4,58	high_impact	3,81	neutral	0,77	damaging	0,12	deleterious	3,9	23,5	0,02	0,35	disease	0,67	disease	0,91	disease	0,64	disease	0,72	4	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,86	low_impact	-2,62	medium_impact	-0,02	high_impact	2,14	0,46	0,8	59,75	10,37	N	0,36	N	0,96	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3983	3983	C	G	MI.12167	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	677	226	A	G	gCc/gGc	5,96	1	0	benign	0,15	neutral	0,42	neutral	2,66	neutral	-0,69	deleterious	-3,65	medium_impact	2,15	neutral	0,75	damaging	0,14	deleterious	4,03	23,7	0,18	0,45	neutral	0,27	disease	0,8	neutral	0,29	neutral	0,47	1	neutral	0,5	deleterious	0,64	neutral	-3	neutral	0,27	medium_impact	-0,04	medium_impact	0,2	medium_impact	0,69	0,71	0,85	59,75	10,37	P	0,57	P	0,79	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3983	3983	C	A	MI.12168	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	677	226	A	D	gCc/gAc	5,96	1	0	probably_damaging	0,98	neutral	0,16	neutral	2,41	deleterious	-3,75	deleterious	-5,46	high_impact	4,5	neutral	0,77	damaging	0,08	deleterious	4,66	24,5	0,01	0,35	disease	0,6	disease	0,93	disease	0,7	disease	0,78	6	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-2,34	medium_impact	-0,13	high_impact	2,74	0,27	0,8	59,75	10,37	P	0,61	P	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3983	3983	C	T	MI.12169	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	677	226	A	V	gCc/gTc	5,96	1	0	probably_damaging	0,96	neutral	0,41	neutral	2,46	neutral	-2,5	deleterious	-3,67	high_impact	3,52	neutral	0,66	damaging	0,08	deleterious	4,49	24,3	0,06	0,35	neutral	0,33	disease	0,9	disease	0,57	disease	0,7	4	neutral	0,96	neutral	0,23	deleterious	2	deleterious	0,78	low_impact	-2,05	medium_impact	0,19	medium_impact	1,89	0,75	0,85	59,75	10,37	P	0,58	P	0,72	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9099	9099	C	A	MI.1217	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	573	191	I	M	atC/atA	4,76	0,72	0	probably_damaging	1	neutral	0,28	neutral	4,29	neutral	-2,21	neutral	-1,14	low_impact	1,09	neutral	0,92	neutral	0,69	deleterious	2,72	20,9	0,39	0,65	neutral	0,36	neutral	0,27	neutral	0,33	neutral	0,45	1	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	0,06	medium_impact	-0,16	0,78	0,9	19,47	23,84	N	0,47	N	0,79	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3985	3985	G	C	MI.12170	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	679	227	E	Q	Gaa/Caa	-1,85	0	0	probably_damaging	1	neutral	0,21	neutral	2,34	deleterious	-3,16	deleterious	-2,76	high_impact	4,25	neutral	0,69	damaging	0,13	deleterious	3,45	23	0,16	0,45	neutral	0,33	disease	0,79	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	-0,05	high_impact	2,52	0,67	0,85	59,12	10,38	N	0,43	N	0,91	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3985	3985	G	A	MI.12171	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	679	227	E	K	Gaa/Aaa	-1,85	0	0	probably_damaging	1	neutral	0,2	neutral	2,36	neutral	-2,72	deleterious	-3,68	high_impact	4,25	neutral	0,67	damaging	0,09	deleterious	4,54	24,3	0,07	0,35	neutral	0,32	disease	0,92	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	-0,06	high_impact	2,52	0,62	0,8	59,12	10,38	N	0,48	N	0,99	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3986	3986	A	C	MI.12172	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	680	227	E	A	gAa/gCa	7,34	1	0	probably_damaging	1	neutral	0,67	neutral	2,35	neutral	-2,92	deleterious	-5,51	high_impact	4,8	neutral	0,71	damaging	0,16	deleterious	3,77	23,4	0,05	0,35	neutral	0,38	disease	0,76	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	0,45	high_impact	3	0,32	0,8	59,12	10,38	P	0,68	P	0,74	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3986	3986	A	G	MI.12173	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	680	227	E	G	gAa/gGa	7,34	1	0	probably_damaging	1	neutral	0,3	neutral	2,32	deleterious	-3,64	deleterious	-6,43	high_impact	4,8	neutral	0,77	damaging	0,16	deleterious	4,37	24,1	0,05	0,35	disease	0,55	disease	0,82	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,07	high_impact	3	0,26	0,8	59,12	10,38	P	0,72	P	0,61	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3986	3986	A	T	MI.12174	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	680	227	E	V	gAa/gTa	7,34	1	0	probably_damaging	1	neutral	0,36	neutral	2,3	deleterious	-4,16	deleterious	-6,45	high_impact	4,8	neutral	0,64	damaging	0,11	deleterious	4,34	24	0,04	0,35	disease	0,54	disease	0,9	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,14	high_impact	3	0,24	0,8	59,12	10,38	P	0,73	P	0,83	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3987	3987	A	C	MI.12175	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	681	227	E	D	gaA/gaC	6,88	1	0	probably_damaging	1	neutral	0,14	neutral	2,39	neutral	-2,37	deleterious	-2,76	high_impact	4,25	neutral	0,73	damaging	0,11	deleterious	3,73	23,3	0,19	0,45	neutral	0,43	disease	0,76	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	-0,17	high_impact	2,52	0,65	0,8	59,12	10,38	P	0,67	P	0,9	polymorphism	0,98	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3987	3987	A	T	MI.12176	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	681	227	E	D	gaA/gaT	6,88	1	0	probably_damaging	1	neutral	0,14	neutral	2,39	neutral	-2,37	deleterious	-2,76	high_impact	4,25	neutral	0,73	damaging	0,11	deleterious	3,84	23,4	0,19	0,45	neutral	0,43	disease	0,76	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	-0,17	high_impact	2,52	0,65	0,8	59,12	10,38	P	0,68	P	0,9	polymorphism	0,98	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3988	3988	T	C	MI.12177	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	682	228	Y	H	Tac/Cac	-0,93	0	0	probably_damaging	1	neutral	0,17	neutral	1,59	deleterious	-5,96	deleterious	-4,57	high_impact	4,79	damaging	0,59	damaging	0,03	deleterious	3,71	23,3	0,1	0,4	disease	0,58	disease	0,83	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	-0,11	high_impact	3	0,13	0,8	59,12	10,6	P	0,66	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3988	3988	T	G	MI.12178	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	682	228	Y	D	Tac/Gac	-0,93	0	0	probably_damaging	1	neutral	0,06	neutral	1,58	deleterious	-6,73	deleterious	-9,15	high_impact	4,79	damaging	0,59	damaging	0,03	deleterious	4,07	23,7	0,04	0,35	neutral	0,37	disease	0,87	disease	0,79	disease	0,77	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	-0,4	high_impact	3	0,09	0,8	59,12	10,6	P	0,52	P	1	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3988	3988	T	A	MI.12179	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	682	228	Y	N	Tac/Aac	-0,93	0	0	probably_damaging	1	neutral	0,09	neutral	1,58	deleterious	-6,45	deleterious	-8,23	high_impact	3,98	damaging	0,57	damaging	0,04	deleterious	4,31	24	0,06	0,35	neutral	0,43	disease	0,86	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	-0,29	high_impact	2,29	0,06	0,8	59,12	10,6	N	0,36	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9099	9099	C	G	MI.1218	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	573	191	I	M	atC/atG	4,76	0,72	0	probably_damaging	1	neutral	0,28	neutral	4,29	neutral	-2,21	neutral	-1,14	low_impact	1,09	neutral	0,92	neutral	0,69	deleterious	2,19	17,45	0,39	0,65	neutral	0,36	neutral	0,27	neutral	0,33	neutral	0,45	1	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	0,06	medium_impact	-0,16	0,78	0,9	19,47	23,84	N	0,46	N	0,79	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3989	3989	A	C	MI.12180	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	683	228	Y	S	tAc/tCc	5,73	1	0	probably_damaging	1	neutral	0,34	neutral	1,59	deleterious	-6,02	deleterious	-8,22	high_impact	4,24	damaging	0,51	damaging	0,06	deleterious	3,74	23,3	0,06	0,35	neutral	0,31	disease	0,85	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,11	high_impact	2,51	0,14	0,8	59,12	10,6	N	0,52	P	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3989	3989	A	T	MI.12181	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	683	228	Y	F	tAc/tTc	5,73	1	0	probably_damaging	1	neutral	1	neutral	1,7	deleterious	-3,78	deleterious	-3,66	high_impact	3,69	damaging	0,59	damaging	0,03	deleterious	3,37	22,9	0,13	0,4	disease	0,59	disease	0,84	disease	0,64	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,82	low_impact	-3,57	high_impact	1,96	high_impact	2,03	0,31	0,8	59,12	10,6	P	0,52	P	0,8	polymorphism	0,99	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3989	3989	A	G	MI.12182	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	683	228	Y	C	tAc/tGc	5,73	1	0	probably_damaging	1	neutral	0,05	neutral	1,57	deleterious	-7,85	deleterious	-8,25	high_impact	4,79	damaging	0,55	damaging	0,03	deleterious	3,51	23,1	0,04	0,35	disease	0,75	disease	0,88	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	-0,44	high_impact	3	0,03	0,8	59,12	10,6	P	0,59	P	1	polymorphism	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3991	3991	A	T	MI.12183	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	685	229	T	S	Aca/Tca	-5,3	0	0	benign	0,19	neutral	0,36	neutral	2,82	neutral	0,23	neutral	0,78	neutral_impact	-0,02	neutral	0,78	neutral	0,7	deleterious	0,09	3,49	0,33	0,5	neutral	0,2	neutral	0,26	neutral	0,16	neutral	0,42	2	neutral	0,57	deleterious	0,59	neutral	-6	neutral	0,18	medium_impact	-0,16	medium_impact	0,14	low_impact	-1,21	0,71	0,85	27,04	41,49	N	0,47	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3991	3991	A	G	MI.12184	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	685	229	T	A	Aca/Gca	-5,3	0	0	benign	0,1	neutral	0,72	neutral	2,95	neutral	1,79	neutral	1,54	neutral_impact	-1,36	neutral	0,74	neutral	0,95	neutral	-1,19	0,01	0,25	0,45	neutral	0,16	neutral	0,08	neutral	0,14	neutral	0,28	4	neutral	0,17	deleterious	0,81	neutral	-6	neutral	0,12	medium_impact	0,15	medium_impact	0,51	low_impact	-2,38	0,29	0,8	27,04	41,49	N	0,44	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3991	3991	A	C	MI.12185	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	685	229	T	P	Aca/Cca	-5,3	0	0	possibly_damaging	0,65	neutral	0,13	neutral	2,74	neutral	-2,17	neutral	-1,67	medium_impact	2,35	neutral	0,63	neutral	0,39	neutral	1,69	14,35	0,06	0,35	neutral	0,44	disease	0,88	disease	0,62	disease	0,8	6	neutral	0,88	neutral	0,24	NA	0	deleterious	0,62	low_impact	-1	medium_impact	-0,19	medium_impact	0,86	0,38	0,8	27,04	41,49	N	0,34	N	0,62	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3992	3992	C	A	MI.12186	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	686	229	T	K	aCa/aAa	2,75	0,11	0,03	benign	0,29	neutral	0,18	neutral	2,78	neutral	-1,19	neutral	-1,37	medium_impact	2,69	neutral	0,64	neutral	0,48	deleterious	2,62	20,3	0,08	0,35	neutral	0,3	disease	0,84	disease	0,58	disease	0,78	6	neutral	0,79	neutral	0,45	neutral	-3	neutral	0,3	medium_impact	-0,39	medium_impact	-0,09	medium_impact	1,16	0,45	0,8	27,04	41,49	N	0,46	N	0,52	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3992	3992	C	T	MI.12187	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	686	229	T	M	aCa/aTa	2,75	0,11	0,03	benign	0,01	neutral	0,27	neutral	2,76	neutral	0,19	neutral	-1,15	neutral_impact	0,4	neutral	0,78	neutral	0,94	neutral	0,92	10,18	0,14	0,4	neutral	0,23	disease	0,58	neutral	0,21	neutral	0,42	2	neutral	0,72	deleterious	0,63	neutral	-6	neutral	0,14	medium_impact	1,12	medium_impact	0,03	medium_impact	-0,84	0,58	0,8	27,04	41,49	N	0,38	N	0,04	polymorphism	1	0,03	rs879051705	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	3994	3994	A	G	MI.12188	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	688	230	N	D	Aac/Gac	-8,97	0	0	possibly_damaging	0,86	neutral	0,18	neutral	2,53	neutral	-2,36	deleterious	-4,57	high_impact	3,89	neutral	0,64	neutral	0,48	deleterious	3,96	23,6	0,5	0,6	neutral	0,33	disease	0,84	disease	0,7	disease	0,75	5	neutral	0,92	neutral	0,16	deleterious	1	deleterious	0,7	low_impact	-1,49	medium_impact	-0,09	high_impact	2,21	0,26	0,8	60,06	10,24	N	0,54	P	0,97	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3994	3994	A	C	MI.12189	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	688	230	N	H	Aac/Cac	-8,97	0	0	probably_damaging	0,99	neutral	0,48	neutral	2,48	deleterious	-3,86	deleterious	-4,57	medium_impact	2,96	neutral	0,68	neutral	0,39	deleterious	3,15	22,6	0,28	0,45	neutral	0,31	disease	0,83	disease	0,65	disease	0,54	1	deleterious	0,99	neutral	0,25	deleterious	1	deleterious	0,74	low_impact	-2,62	medium_impact	0,26	medium_impact	1,4	0,16	0,8	60,06	10,24	N	0,33	N	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9100	9100	A	G	MI.1219	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	574	192	I	V	Atc/Gtc	-10,98	0	0	benign	0,08	neutral	0,57	neutral	4,36	neutral	-0,45	neutral	0,54	neutral_impact	0,76	neutral	0,96	neutral	0,75	neutral	1,3	12,26	0,59	0,7	neutral	0,35	neutral	0,22	neutral	0,31	neutral	0,39	2	neutral	0,35	deleterious	0,75	neutral	-6	neutral	0,15	medium_impact	0,25	medium_impact	0,36	medium_impact	-0,45	0,57	0,9	12,83	11,48	N	0,32	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3994	3994	A	T	MI.12190	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	688	230	N	Y	Aac/Tac	-8,97	0	0	probably_damaging	0,99	neutral	1	neutral	2,47	deleterious	-4,48	deleterious	-7,31	medium_impact	3,05	neutral	0,67	neutral	0,36	deleterious	3,81	23,4	0,06	0,35	disease	0,51	disease	0,91	disease	0,67	disease	0,74	5	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,8	low_impact	-2,62	high_impact	1,96	medium_impact	1,48	0,14	0,8	60,06	10,24	N	0,24	N	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3995	3995	A	T	MI.12191	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	689	230	N	I	aAc/aTc	8,49	1	0	probably_damaging	0,98	neutral	0,46	neutral	2,48	deleterious	-3,76	deleterious	-8,22	medium_impact	2,92	neutral	0,69	neutral	0,56	deleterious	3,9	23,5	0,08	0,35	disease	0,54	disease	0,94	disease	0,62	disease	0,78	6	neutral	0,98	neutral	0,24	deleterious	1	deleterious	0,8	low_impact	-2,34	medium_impact	0,24	medium_impact	1,36	0,11	0,8	60,06	10,24	P	0,54	P	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3995	3995	A	C	MI.12192	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	689	230	N	T	aAc/aCc	8,49	1	0	possibly_damaging	0,81	neutral	0,38	neutral	2,53	neutral	-2,28	deleterious	-5,47	high_impact	3,63	neutral	0,61	neutral	0,46	deleterious	3,43	23	0,27	0,45	neutral	0,33	disease	0,87	disease	0,63	disease	0,71	4	neutral	0,82	neutral	0,29	deleterious	1	deleterious	0,7	low_impact	-1,34	medium_impact	0,16	medium_impact	1,98	0,17	0,8	60,06	10,24	P	0,64	P	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3995	3995	A	G	MI.12193	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	689	230	N	S	aAc/aGc	8,49	1	0	benign	0,26	neutral	0,41	neutral	2,64	neutral	-1,02	deleterious	-4,55	medium_impact	2,15	neutral	0,75	neutral	0,6	deleterious	3,09	22,5	0,53	0,6	neutral	0,19	disease	0,59	neutral	0,4	neutral	0,41	2	neutral	0,5	deleterious	0,58	neutral	-3	neutral	0,34	medium_impact	-0,32	medium_impact	0,19	medium_impact	0,69	0,1	0,8	60,06	10,24	P	0,66	P	0,9	polymorphism	1	0,13	.	.	.	.	.	.	.	CPD	0,15	A3995G	MELAS	.	.	Reported	1
chrM	3996	3996	C	A	MI.12194	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	690	230	N	K	aaC/aaA	8,49	1	0	possibly_damaging	0,88	neutral	0,26	neutral	2,54	neutral	-2,19	deleterious	-5,48	high_impact	3,54	neutral	0,63	neutral	0,35	deleterious	4,57	24,4	0,44	0,55	neutral	0,16	disease	0,91	disease	0,7	disease	0,75	5	neutral	0,91	neutral	0,19	deleterious	1	deleterious	0,71	low_impact	-1,56	medium_impact	0,02	medium_impact	1,9	0,31	0,8	60,06	10,24	P	0,62	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3996	3996	C	G	MI.12195	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	690	230	N	K	aaC/aaG	8,49	1	0	possibly_damaging	0,88	neutral	0,26	neutral	2,54	neutral	-2,19	deleterious	-5,48	high_impact	3,54	neutral	0,63	neutral	0,35	deleterious	4,07	23,7	0,44	0,55	neutral	0,16	disease	0,91	disease	0,7	disease	0,75	5	neutral	0,91	neutral	0,19	deleterious	1	deleterious	0,71	low_impact	-1,56	medium_impact	0,02	medium_impact	1,9	0,31	0,8	60,06	10,24	P	0,61	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3997	3997	A	T	MI.12196	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	691	231	I	F	Att/Ttt	-2,77	0	0	probably_damaging	1	neutral	0,99	neutral	2,46	deleterious	-3	deleterious	-3,63	high_impact	3,62	neutral	0,68	damaging	0,15	deleterious	3,6	23,2	0,16	0,45	neutral	0,38	disease	0,79	disease	0,67	disease	0,68	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	1,39	medium_impact	1,97	0,64	0,8	59,43	10,6	N	0,29	N	0,95	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3997	3997	A	C	MI.12197	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	691	231	I	L	Att/Ctt	-2,77	0	0	probably_damaging	1	neutral	1	neutral	2,89	neutral	0,3	neutral	-1,8	medium_impact	2,58	neutral	0,71	damaging	0,13	deleterious	3,59	23,2	0,28	0,45	neutral	0,15	disease	0,68	disease	0,6	disease	0,66	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,68	low_impact	-3,57	high_impact	1,96	medium_impact	1,07	0,66	0,8	59,43	10,6	N	0,24	N	0,82	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3997	3997	A	G	MI.12198	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	691	231	I	V	Att/Gtt	-2,77	0	0	probably_damaging	1	neutral	0,31	neutral	2,61	neutral	-1,06	neutral	-0,9	medium_impact	2,81	neutral	0,77	damaging	0,19	deleterious	2,9	21,9	0,5	0,6	neutral	0,2	neutral	0,46	disease	0,59	neutral	0,46	1	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,68	low_impact	-3,57	medium_impact	0,08	medium_impact	1,27	0,58	0,8	59,43	10,6	N	0,34	N	0,73	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3998	3998	T	A	MI.12199	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	692	231	I	N	aTt/aAt	8,49	1	0	probably_damaging	1	neutral	0,25	neutral	2,42	deleterious	-5,15	deleterious	-6,37	high_impact	3,98	neutral	0,73	damaging	0,15	deleterious	4,48	24,2	0,13	0,4	disease	0,6	disease	0,82	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,01	high_impact	2,29	0,33	0,8	59,43	10,6	P	0,61	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8582	8582	C	A	MI.122	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	56	19	A	D	gCc/gAc	-0,57	0	0	probably_damaging	1	deleterious	0	neutral	4,58	neutral	-2,54	deleterious	-3,05	low_impact	0,8	neutral	0,77	neutral	0,45	deleterious	4,3	24	0,13	0,65	disease	0,83	disease	0,77	disease	0,61	disease	0,77	5	deleterious	1	neutral	0	deleterious	2	deleterious	0,85	low_impact	-3,6	low_impact	-1,4	medium_impact	-0,41	0,46	0,9	29,65	29,28	N	0,24	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9100	9100	A	T	MI.1220	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	574	192	I	F	Atc/Ttc	-10,98	0	0	possibly_damaging	0,6	neutral	0,55	neutral	4,33	neutral	-0,99	neutral	-1,19	low_impact	0,94	neutral	0,91	neutral	0,76	deleterious	3,47	23	0,42	0,65	disease	0,54	disease	0,59	neutral	0,33	neutral	0,48	0	neutral	0,55	deleterious	0,48	neutral	-3	deleterious	0,56	medium_impact	-0,92	medium_impact	0,34	medium_impact	-0,29	0,72	0,9	12,83	11,48	N	0,27	N	0,28	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3998	3998	T	C	MI.12200	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	692	231	I	T	aTt/aCt	8,49	1	0	probably_damaging	1	neutral	0,22	neutral	2,45	deleterious	-3,43	deleterious	-4,53	high_impact	3,98	neutral	0,66	damaging	0,14	deleterious	3,44	23	0,07	0,35	neutral	0,29	disease	0,76	disease	0,58	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,74	low_impact	-3,57	medium_impact	-0,03	high_impact	2,29	0,4	0,8	59,43	10,6	P	0,62	P	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3998	3998	T	G	MI.12201	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	692	231	I	S	aTt/aGt	8,49	1	0	probably_damaging	1	neutral	0,31	neutral	2,43	deleterious	-4,1	deleterious	-5,44	high_impact	4,17	neutral	0,72	damaging	0,19	deleterious	4,33	24	0,03	0,35	neutral	0,43	disease	0,83	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,08	high_impact	2,45	0,29	0,8	59,43	10,6	P	0,63	P	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3999	3999	T	A	MI.12202	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	693	231	I	M	atT/atA	7,34	1	0	probably_damaging	1	neutral	0,42	neutral	2,56	neutral	-1,54	deleterious	-2,68	medium_impact	2,09	neutral	0,73	damaging	0,15	deleterious	3,77	23,4	0,38	0,5	neutral	0,24	disease	0,63	disease	0,55	neutral	0,42	2	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,68	low_impact	-3,57	medium_impact	0,2	medium_impact	0,64	0,65	0,8	59,43	10,6	P	0,56	P	0,74	polymorphism	0,98	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	3999	3999	T	G	MI.12203	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	693	231	I	M	atT/atG	7,34	1	0	probably_damaging	1	neutral	0,42	neutral	2,56	neutral	-1,54	deleterious	-2,68	medium_impact	2,09	neutral	0,73	damaging	0,15	deleterious	3,45	23	0,38	0,5	neutral	0,24	disease	0,63	disease	0,55	neutral	0,42	2	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,68	low_impact	-3,57	medium_impact	0,2	medium_impact	0,64	0,65	0,8	59,43	10,6	P	0,56	P	0,74	polymorphism	0,98	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4000	4000	A	G	MI.12204	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	694	232	I	V	Att/Gtt	-2,54	0	0	possibly_damaging	0,53	neutral	0,5	neutral	2,77	neutral	0,13	neutral	-0,77	low_impact	1,88	neutral	0,71	damaging	0,09	deleterious	3,11	22,5	0,43	0,55	neutral	0,17	neutral	0,4	disease	0,56	neutral	0,48	0	neutral	0,52	deleterious	0,49	neutral	-3	neutral	0,33	medium_impact	-0,8	medium_impact	0,28	medium_impact	0,45	0,51	0,8	24,84	12,94	N	0,28	N	0,5	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4000	4000	A	C	MI.12205	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	694	232	I	L	Att/Ctt	-2,54	0	0	benign	0,26	neutral	0,65	neutral	2,85	neutral	-0,6	neutral	0,81	neutral_impact	0	neutral	0,84	neutral	0,6	neutral	1,1	11,24	0,27	0,45	neutral	0,14	neutral	0,16	neutral	0,26	neutral	0,23	5	neutral	0,25	deleterious	0,7	neutral	-6	neutral	0,2	medium_impact	-0,32	medium_impact	0,43	low_impact	-1,19	0,57	0,8	24,84	12,94	N	0,26	N	0,62	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4000	4000	A	T	MI.12206	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	694	232	I	F	Att/Ttt	-2,54	0	0	possibly_damaging	0,89	neutral	0,7	neutral	2,64	neutral	-0,57	neutral	-2,09	low_impact	1,83	neutral	0,68	damaging	0,08	deleterious	3,82	23,4	0,2	0,45	neutral	0,27	disease	0,74	disease	0,59	disease	0,7	4	neutral	0,87	neutral	0,41	neutral	-3	deleterious	0,66	low_impact	-1,6	medium_impact	0,48	medium_impact	0,41	0,58	0,8	24,84	12,94	N	0,21	N	0,91	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4001	4001	T	A	MI.12207	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	695	232	I	N	aTt/aAt	0,91	0,42	0	probably_damaging	0,97	neutral	0,31	neutral	2,61	deleterious	-4,05	deleterious	-4,67	high_impact	3,8	neutral	0,68	damaging	0,1	deleterious	4,39	24,1	0,07	0,35	disease	0,67	disease	0,79	disease	0,59	disease	0,72	4	neutral	0,97	neutral	0,17	deleterious	2	deleterious	0,79	low_impact	-2,17	medium_impact	0,08	high_impact	2,13	0,28	0,8	24,84	12,94	N	0,35	N	0,99	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4001	4001	T	G	MI.12208	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	695	232	I	S	aTt/aGt	0,91	0,42	0	probably_damaging	0,91	neutral	0,4	neutral	2,65	neutral	-2,64	deleterious	-3,74	high_impact	3,8	neutral	0,7	damaging	0,09	deleterious	4,3	24	0,03	0,35	neutral	0,49	disease	0,77	disease	0,59	disease	0,71	4	neutral	0,91	neutral	0,25	deleterious	2	deleterious	0,72	low_impact	-1,69	medium_impact	0,18	high_impact	2,13	0,26	0,8	24,84	12,94	N	0,3	N	0,94	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4001	4001	T	C	MI.12209	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	695	232	I	T	aTt/aCt	0,91	0,42	0	possibly_damaging	0,88	neutral	0,39	neutral	2,68	neutral	-1,84	deleterious	-2,97	medium_impact	2,9	neutral	0,7	damaging	0,08	deleterious	3,39	23	0,08	0,35	neutral	0,42	disease	0,62	disease	0,58	disease	0,69	4	neutral	0,88	neutral	0,26	NA	0	deleterious	0,64	low_impact	-1,56	medium_impact	0,17	medium_impact	1,34	0,25	0,8	24,84	12,94	N	0,29	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9100	9100	A	C	MI.1221	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	574	192	I	L	Atc/Ctc	-10,98	0	0	benign	0,08	neutral	0,82	neutral	4,38	neutral	-0,16	neutral	-0,03	neutral_impact	0,22	neutral	0,87	neutral	0,77	deleterious	2,04	16,5	0,4	0,65	neutral	0,22	neutral	0,31	neutral	0,26	neutral	0,44	1	neutral	0,08	deleterious	0,87	neutral	-6	neutral	0,15	medium_impact	0,25	medium_impact	0,66	medium_impact	-0,91	0,61	0,9	12,83	11,48	N	0,33	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4002	4002	T	A	MI.12210	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	696	232	I	M	atT/atA	7,34	0,98	0	possibly_damaging	0,52	neutral	0,22	neutral	2,66	neutral	-2,46	neutral	-0,15	low_impact	1	neutral	0,84	neutral	0,85	deleterious	2,29	18,08	0,22	0,45	neutral	0,38	neutral	0,36	neutral	0,36	neutral	0,46	1	neutral	0,76	neutral	0,35	neutral	-3	neutral	0,27	medium_impact	-0,78	medium_impact	-0,03	medium_impact	-0,32	0,62	0,8	24,84	12,94	P	0,65	P	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4002	4002	T	G	MI.12211	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	696	232	I	M	atT/atG	7,34	0,98	0	possibly_damaging	0,52	neutral	0,22	neutral	2,66	neutral	-2,46	neutral	-0,15	low_impact	1	neutral	0,84	neutral	0,85	deleterious	1,96	15,98	0,22	0,45	neutral	0,38	neutral	0,36	neutral	0,36	neutral	0,46	1	neutral	0,76	neutral	0,35	neutral	-3	neutral	0,27	medium_impact	-0,78	medium_impact	-0,03	medium_impact	-0,32	0,62	0,8	24,84	12,94	P	0,66	P	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4003	4003	A	T	MI.12212	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	697	233	M	L	Ata/Tta	-8,51	0	0	benign	0,02	neutral	0,65	neutral	3,12	neutral	2,19	neutral	-0,5	neutral_impact	-0,1	neutral	0,88	neutral	0,91	neutral	-1,05	0,01	0,28	0,45	neutral	0,17	neutral	0,29	neutral	0,38	neutral	0,43	1	neutral	0,32	deleterious	0,82	neutral	-6	neutral	0,12	medium_impact	0,84	medium_impact	0,43	low_impact	-1,28	0,47	0,8	25,79	30,42	N	0,34	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4003	4003	A	G	MI.12213	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	697	233	M	V	Ata/Gta	-8,51	0	0	benign	0,4	neutral	0,49	neutral	2,94	neutral	1,27	neutral	-2,04	low_impact	1,59	neutral	0,88	neutral	0,54	neutral	0,97	10,52	0,23	0,45	neutral	0,15	disease	0,66	neutral	0,5	neutral	0,45	1	neutral	0,45	deleterious	0,55	neutral	-6	neutral	0,29	medium_impact	-0,59	medium_impact	0,27	medium_impact	0,2	0,53	0,8	25,79	30,42	N	0,29	N	0,51	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4003	4003	A	C	MI.12214	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	697	233	M	L	Ata/Cta	-8,51	0	0	benign	0,02	neutral	0,65	neutral	3,12	neutral	2,19	neutral	-0,5	neutral_impact	-0,1	neutral	0,88	neutral	0,91	neutral	-1,12	0,01	0,28	0,45	neutral	0,17	neutral	0,29	neutral	0,38	neutral	0,43	1	neutral	0,32	deleterious	0,82	neutral	-6	neutral	0,12	medium_impact	0,84	medium_impact	0,43	low_impact	-1,28	0,47	0,8	25,79	30,42	N	0,34	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4004	4004	T	A	MI.12215	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	698	233	M	K	aTa/aAa	-0,24	0	0	possibly_damaging	0,84	neutral	0,29	neutral	2,74	neutral	-1,77	deleterious	-4,27	medium_impact	3,44	damaging	0,6	damaging	0,09	deleterious	2,09	16,81	0,04	0,35	neutral	0,39	disease	0,86	disease	0,7	disease	0,77	5	neutral	0,87	neutral	0,23	NA	0	deleterious	0,66	low_impact	-1,43	medium_impact	0,06	medium_impact	1,82	0,29	0,8	25,79	30,42	N	0,34	N	0,92	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4004	4004	T	C	MI.12216	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	698	233	M	T	aTa/aCa	-0,24	0	0	possibly_damaging	0,68	neutral	0,39	neutral	2,79	neutral	-0,29	deleterious	-3,59	low_impact	1,6	neutral	0,79	damaging	0,15	neutral	1,09	11,18	0,09	0,4	neutral	0,18	disease	0,7	neutral	0,5	neutral	0,5	0	neutral	0,71	neutral	0,36	neutral	-3	deleterious	0,48	low_impact	-1,06	medium_impact	0,17	medium_impact	0,21	0,22	0,8	25,79	30,42	N	0,23	N	0,66	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4005	4005	A	C	MI.12217	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	699	233	M	I	atA/atC	4,58	0,65	0	benign	0,29	neutral	0,4	neutral	2,86	neutral	0,61	neutral	-1,68	low_impact	1,55	neutral	0,87	damaging	0,27	neutral	1,6	13,87	0,3	0,45	neutral	0,14	disease	0,72	neutral	0,47	neutral	0,5	0	neutral	0,52	deleterious	0,56	neutral	-6	neutral	0,29	medium_impact	-0,39	medium_impact	0,18	medium_impact	0,17	0,53	0,8	25,79	30,42	N	0,33	N	0,37	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4005	4005	A	T	MI.12218	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	699	233	M	I	atA/atT	4,58	0,65	0	benign	0,29	neutral	0,4	neutral	2,86	neutral	0,61	neutral	-1,68	low_impact	1,55	neutral	0,87	damaging	0,27	neutral	1,67	14,24	0,3	0,45	neutral	0,14	disease	0,72	neutral	0,47	neutral	0,5	0	neutral	0,52	deleterious	0,56	neutral	-6	neutral	0,29	medium_impact	-0,39	medium_impact	0,18	medium_impact	0,17	0,53	0,8	25,79	30,42	N	0,34	N	0,37	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4006	4006	A	T	MI.12219	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	700	234	M	L	Ata/Tta	-1,62	0	0	probably_damaging	0,98	neutral	0,71	neutral	2,73	neutral	0,57	deleterious	-2,75	medium_impact	2,44	damaging	0,57	damaging	0,03	deleterious	3,33	22,9	0,26	0,45	neutral	0,18	disease	0,77	disease	0,63	disease	0,62	2	deleterious	0,98	neutral	0,37	deleterious	1	deleterious	0,73	low_impact	-2,34	medium_impact	0,49	medium_impact	0,94	0,37	0,8	58,49	10,65	N	0,23	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9101	9101	T	G	MI.1222	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	575	192	I	S	aTc/aGc	4,76	0,99	0,01	benign	0,16	neutral	0,34	neutral	4,36	neutral	-0,41	neutral	0,8	neutral_impact	0,66	neutral	0,91	neutral	0,89	deleterious	2,5	19,47	0,34	0,65	disease	0,5	disease	0,56	neutral	0,33	neutral	0,46	1	neutral	0,6	deleterious	0,59	neutral	-6	neutral	0,29	medium_impact	-0,07	medium_impact	0,13	medium_impact	-0,53	0,66	0,9	12,83	11,48	N	0,52	P	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4006	4006	A	C	MI.12220	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	700	234	M	L	Ata/Cta	-1,62	0	0	probably_damaging	0,98	neutral	0,71	neutral	2,73	neutral	0,57	deleterious	-2,75	medium_impact	2,44	damaging	0,57	damaging	0,03	deleterious	3,26	22,8	0,26	0,45	neutral	0,18	disease	0,77	disease	0,63	disease	0,62	2	deleterious	0,98	neutral	0,37	deleterious	1	deleterious	0,73	low_impact	-2,34	medium_impact	0,49	medium_impact	0,94	0,37	0,8	58,49	10,65	N	0,23	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4006	4006	A	G	MI.12221	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	700	234	M	V	Ata/Gta	-1,62	0	0	probably_damaging	0,99	neutral	0,45	neutral	2,7	neutral	0,97	deleterious	-3,66	medium_impact	2,53	damaging	0,54	damaging	0,06	deleterious	2,74	21	0,29	0,45	neutral	0,2	disease	0,75	disease	0,69	disease	0,62	2	deleterious	0,99	neutral	0,23	deleterious	1	deleterious	0,75	low_impact	-2,62	medium_impact	0,23	medium_impact	1,02	0,42	0,8	58,49	10,65	N	0,25	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4007	4007	T	A	MI.12222	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	701	234	M	K	aTa/aAa	8,49	1	0	probably_damaging	1	neutral	0,24	neutral	2,61	neutral	-2,66	deleterious	-5,53	high_impact	4,46	damaging	0,56	damaging	0,04	deleterious	4,14	23,8	0,04	0,35	neutral	0,47	disease	0,88	disease	0,76	disease	0,75	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,01	high_impact	2,71	0,2	0,8	58,49	10,65	P	0,67	P	1	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4007	4007	T	C	MI.12223	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	701	234	M	T	aTa/aCa	8,49	1	0	probably_damaging	1	neutral	0,34	neutral	2,63	neutral	-1,34	deleterious	-5,51	high_impact	4,12	damaging	0,49	damaging	0,08	deleterious	3,08	22,5	0,08	0,35	neutral	0,29	disease	0,83	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,11	high_impact	2,41	0,12	0,8	58,49	10,65	P	0,61	P	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4008	4008	A	C	MI.12224	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	702	234	M	I	atA/atC	4,58	1	0	probably_damaging	0,99	neutral	0,51	neutral	2,7	neutral	0,27	deleterious	-3,65	medium_impact	2,5	damaging	0,57	damaging	0,05	deleterious	3,24	22,8	0,27	0,45	neutral	0,28	disease	0,78	disease	0,64	neutral	0,5	0	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,78	low_impact	-2,62	medium_impact	0,29	medium_impact	1	0,33	0,8	58,49	10,65	N	0,45	N	0,95	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4008	4008	A	T	MI.12225	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	702	234	M	I	atA/atT	4,58	1	0	probably_damaging	0,99	neutral	0,51	neutral	2,7	neutral	0,27	deleterious	-3,65	medium_impact	2,5	damaging	0,57	damaging	0,05	deleterious	3,32	22,9	0,27	0,45	neutral	0,28	disease	0,78	disease	0,64	neutral	0,5	0	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,78	low_impact	-2,62	medium_impact	0,29	medium_impact	1	0,33	0,8	58,49	10,65	N	0,46	N	0,95	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4009	4009	A	C	MI.12226	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	703	235	N	H	Aac/Cac	4,58	1	0	probably_damaging	1	neutral	0,54	neutral	2,66	neutral	-2,79	deleterious	-4,61	high_impact	3,88	neutral	0,68	damaging	0,08	deleterious	3,17	22,7	0,29	0,45	neutral	0,42	disease	0,84	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,31	high_impact	2,2	0,38	0,8	59,12	10,45	N	0,5	N	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4009	4009	A	G	MI.12227	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	703	235	N	D	Aac/Gac	4,58	1	0	probably_damaging	1	neutral	0,2	neutral	2,69	neutral	-1,87	deleterious	-4,6	high_impact	3,88	neutral	0,71	damaging	0,11	deleterious	3,93	23,5	0,36	0,5	neutral	0,33	disease	0,82	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,74	low_impact	-3,57	medium_impact	-0,06	high_impact	2,2	0,44	0,8	59,12	10,45	P	0,6	P	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4009	4009	A	T	MI.12228	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	703	235	N	Y	Aac/Tac	4,58	1	0	probably_damaging	1	neutral	1	neutral	2,66	deleterious	-3,08	deleterious	-7,37	high_impact	3,54	neutral	0,71	damaging	0,08	deleterious	3,77	23,4	0,1	0,4	neutral	0,4	disease	0,9	disease	0,62	disease	0,71	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,78	low_impact	-3,57	high_impact	1,96	medium_impact	1,9	0,32	0,8	59,12	10,45	N	0,4	N	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4010	4010	A	T	MI.12229	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	704	235	N	I	aAc/aTc	8,49	1	0	probably_damaging	1	neutral	0,39	neutral	2,68	neutral	-2,08	deleterious	-8,3	high_impact	3,88	neutral	0,73	damaging	0,11	deleterious	3,91	23,5	0,13	0,4	neutral	0,2	disease	0,92	disease	0,56	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	0,17	high_impact	2,2	0,24	0,8	59,12	10,45	P	0,56	P	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9101	9101	T	A	MI.1223	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	575	192	I	N	aTc/aAc	4,76	0,99	0,01	possibly_damaging	0,44	neutral	0,25	neutral	4,29	neutral	-2,02	neutral	-0,32	low_impact	1,38	neutral	0,87	neutral	0,49	deleterious	2,86	21,7	0,28	0,65	disease	0,66	disease	0,65	disease	0,54	disease	0,69	4	neutral	0,71	neutral	0,41	neutral	-3	deleterious	0,56	medium_impact	-0,66	medium_impact	0,02	medium_impact	0,09	0,69	0,9	12,83	11,48	N	0,52	P	0,22	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4010	4010	A	C	MI.12230	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	704	235	N	T	aAc/aCc	8,49	1	0	probably_damaging	1	neutral	0,39	neutral	2,73	neutral	-0,96	deleterious	-5,52	medium_impact	3,34	neutral	0,64	damaging	0,1	deleterious	3,46	23	0,25	0,45	neutral	0,19	disease	0,85	disease	0,57	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,17	medium_impact	1,73	0,46	0,8	59,12	10,45	P	0,51	P	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4010	4010	A	G	MI.12231	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	704	235	N	S	aAc/aGc	8,49	1	0	probably_damaging	1	neutral	0,4	neutral	3	neutral	1,19	deleterious	-4,59	low_impact	1,03	neutral	0,65	damaging	0,11	deleterious	3,07	22,4	0,41	0,5	neutral	0,16	neutral	0,39	neutral	0,39	neutral	0,37	3	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,67	low_impact	-3,57	medium_impact	0,18	medium_impact	-0,29	0,43	0,8	59,12	10,45	P	0,53	P	0,9	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4011	4011	C	G	MI.12232	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	705	235	N	K	aaC/aaG	8,49	1	0	probably_damaging	1	neutral	0,29	neutral	2,72	neutral	-1,15	deleterious	-5,53	high_impact	3,88	neutral	0,75	damaging	0,11	deleterious	4,04	23,7	0,26	0,45	neutral	0,23	disease	0,9	disease	0,66	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,06	high_impact	2,2	0,48	0,8	59,12	10,45	P	0,62	P	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4011	4011	C	A	MI.12233	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	705	235	N	K	aaC/aaA	8,49	1	0	probably_damaging	1	neutral	0,29	neutral	2,72	neutral	-1,15	deleterious	-5,53	high_impact	3,88	neutral	0,75	damaging	0,11	deleterious	4,46	24,2	0,26	0,45	neutral	0,23	disease	0,9	disease	0,66	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	0,06	high_impact	2,2	0,48	0,8	59,12	10,45	P	0,62	P	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4012	4012	A	C	MI.12234	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	706	236	T	P	Acc/Ccc	-0,7	0	0	benign	0,41	neutral	0,16	neutral	2,7	neutral	-2,6	deleterious	-4,43	high_impact	3,54	neutral	0,67	neutral	0,45	neutral	1,66	14,2	0,06	0,35	neutral	0,47	disease	0,83	disease	0,61	disease	0,71	4	neutral	0,81	neutral	0,38	neutral	-2	neutral	0,42	medium_impact	-0,6	medium_impact	-0,13	medium_impact	1,9	0,49	0,8	16,98	36,64	N	0,4	N	0,27	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4012	4012	A	T	MI.12235	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	706	236	T	S	Acc/Tcc	-0,7	0	0	benign	0,12	neutral	0,69	neutral	2,76	neutral	0,39	deleterious	-2,61	low_impact	0,98	neutral	0,79	neutral	0,76	neutral	1,3	12,27	0,35	0,5	neutral	0,14	disease	0,5	neutral	0,27	neutral	0,43	1	neutral	0,2	deleterious	0,79	neutral	-6	neutral	0,14	medium_impact	0,06	medium_impact	0,47	medium_impact	-0,33	0,57	0,8	16,98	36,64	N	0,26	N	0,1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4012	4012	A	G	MI.12236	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	706	236	T	A	Acc/Gcc	-0,7	0	0	benign	0	neutral	0,68	neutral	2,85	neutral	2,04	deleterious	-2,76	neutral_impact	0,17	neutral	0,77	neutral	0,89	neutral	-0,35	0,52	0,26	0,45	neutral	0,12	neutral	0,23	neutral	0,29	neutral	0,42	2	neutral	0,31	deleterious	0,84	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,46	low_impact	-1,04	0,41	0,8	16,98	36,64	N	0,3	N	0	polymorphism	1	0,08	rs201610884	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4013	4013	C	A	MI.12237	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	707	236	T	N	aCc/aAc	1,6	0	0	benign	0,41	neutral	0,6	neutral	2,72	neutral	-2,21	deleterious	-3,91	high_impact	3,54	neutral	0,7	neutral	0,55	deleterious	1,95	15,92	0,3	0,45	neutral	0,39	disease	0,69	neutral	0,38	neutral	0,49	0	neutral	0,37	deleterious	0,6	neutral	-2	neutral	0,35	medium_impact	-0,6	medium_impact	0,37	medium_impact	1,9	0,51	0,8	16,98	36,64	N	0,34	N	0,28	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4013	4013	C	G	MI.12238	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	707	236	T	S	aCc/aGc	1,6	0	0	benign	0,12	neutral	0,69	neutral	2,76	neutral	0,39	deleterious	-2,61	low_impact	0,98	neutral	0,79	neutral	0,76	neutral	1,69	14,36	0,35	0,5	neutral	0,14	disease	0,5	neutral	0,27	neutral	0,43	1	neutral	0,2	deleterious	0,79	neutral	-6	neutral	0,14	medium_impact	0,06	medium_impact	0,47	medium_impact	-0,33	0,57	0,8	16,98	36,64	N	0,26	N	0,1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4013	4013	C	T	MI.12239	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	707	236	T	I	aCc/aTc	1,6	0	0	benign	0,12	neutral	1	neutral	2,78	neutral	0,52	deleterious	-4,19	low_impact	1,3	neutral	0,78	neutral	0,91	deleterious	2,12	17,01	0,14	0,4	neutral	0,13	disease	0,69	neutral	0,29	neutral	0,49	0	neutral	0,12	deleterious	0,94	neutral	-6	neutral	0,16	medium_impact	0,06	high_impact	1,96	medium_impact	-0,05	0,68	0,85	16,98	36,64	N	0,26	N	0,14	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9101	9101	T	C	MI.1224	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	575	192	I	T	aTc/aCc	4,76	0,99	0,01	benign	0,01	neutral	1	neutral	4,38	neutral	-0,1	neutral	3,43	neutral_impact	-1,09	damaging	0,34	neutral	0,37	neutral	-1,17	0,01	0,46	0,65	neutral	0,32	neutral	0,05	neutral	0,24	neutral	0,2	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,11	medium_impact	1,14	high_impact	1,98	low_impact	-2,03	0,71	0,9	12,83	11,48	P	0,8	P	0,67	disease_causing_automatic	0	0,02	rs199476134	Pathogenic	Leber's_optic_atrophy	RCV000010277.2	MedGen:OMIM:SNOMED_CT	.	.	.	.	T9101C	LHON	+	-	Reported	3
chrM	4015	4015	C	G	MI.12240	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	709	237	L	V	Ctc/Gtc	-7,36	0	0	probably_damaging	1	neutral	0,29	neutral	2,24	neutral	-2,44	neutral	-2,47	medium_impact	2,62	neutral	0,73	neutral	0,6	deleterious	3,51	23,1	0,25	0,45	neutral	0,28	neutral	0,44	disease	0,51	neutral	0,44	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,06	medium_impact	1,1	0,41	0,8	18,87	31,55	N	0,4	N	0,41	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4015	4015	C	T	MI.12241	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	709	237	L	F	Ctc/Ttc	-7,36	0	0	probably_damaging	1	neutral	0,78	neutral	2,24	neutral	-2,47	deleterious	-3,25	medium_impact	2,41	neutral	0,8	neutral	0,9	deleterious	3,99	23,6	0,18	0,45	neutral	0,31	neutral	0,43	neutral	0,42	neutral	0,42	2	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,58	medium_impact	0,92	0,39	0,8	18,87	31,55	N	0,27	N	0,24	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4015	4015	C	A	MI.12242	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	709	237	L	I	Ctc/Atc	-7,36	0	0	probably_damaging	1	neutral	0,69	neutral	2,28	neutral	-2,14	neutral	-1,58	medium_impact	2,31	neutral	0,82	neutral	0,84	deleterious	4,11	23,8	0,28	0,45	neutral	0,28	neutral	0,37	neutral	0,35	neutral	0,42	2	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,47	medium_impact	0,83	0,48	0,8	18,87	31,55	N	0,29	N	0,39	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4016	4016	T	A	MI.12243	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	710	237	L	H	cTc/cAc	-0,7	0	0	probably_damaging	1	neutral	0,26	neutral	2,09	deleterious	-6,41	deleterious	-6,09	high_impact	4,5	neutral	0,7	neutral	0,46	deleterious	4,18	23,8	0,03	0,35	disease	0,7	disease	0,72	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,02	high_impact	2,74	0,22	0,8	18,87	31,55	N	0,47	N	0,87	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4016	4016	T	C	MI.12244	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	710	237	L	P	cTc/cCc	-0,7	0	0	probably_damaging	1	neutral	0,1	neutral	2,09	deleterious	-6,32	deleterious	-6,18	high_impact	3,94	neutral	0,78	neutral	0,44	deleterious	4	23,6	0,02	0,35	disease	0,73	disease	0,75	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,26	high_impact	2,25	0,24	0,8	18,87	31,55	N	0,36	N	0,95	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4016	4016	T	G	MI.12245	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	710	237	L	R	cTc/cGc	-0,7	0	0	probably_damaging	1	neutral	0,17	neutral	2,09	deleterious	-5,77	deleterious	-5,3	high_impact	4,5	neutral	0,66	neutral	0,44	deleterious	4,29	24	0,01	0,35	disease	0,71	disease	0,84	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	-0,11	high_impact	2,74	0,11	0,8	18,87	31,55	N	0,5	N	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4018	4018	A	G	MI.12246	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	712	238	T	A	Acc/Gcc	-8,74	0	0	probably_damaging	1	neutral	0,43	neutral	2,79	neutral	0,59	neutral	-1,79	medium_impact	1,94	neutral	0,68	neutral	0,58	deleterious	3,58	23,2	0,23	0,45	neutral	0,15	neutral	0,41	neutral	0,43	neutral	0,45	1	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,65	low_impact	-3,57	medium_impact	0,21	medium_impact	0,51	0,51	0,8	51,26	9,33	N	0,31	N	0,65	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4018	4018	A	C	MI.12247	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	712	238	T	P	Acc/Ccc	-8,74	0	0	probably_damaging	1	neutral	0,14	neutral	2,69	deleterious	-3,06	deleterious	-3,29	high_impact	3,94	neutral	0,63	neutral	0,3	deleterious	3,56	23,1	0,05	0,35	disease	0,54	disease	0,83	disease	0,6	disease	0,73	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	-0,17	high_impact	2,25	0,44	0,8	51,26	9,33	N	0,36	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4018	4018	A	T	MI.12248	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	712	238	T	S	Acc/Tcc	-8,74	0	0	probably_damaging	1	neutral	0,59	neutral	2,79	neutral	-1,31	neutral	0,27	neutral_impact	0,4	neutral	0,75	neutral	0,86	deleterious	0,65	8,5	0,36	0,5	neutral	0,23	neutral	0,06	neutral	0,24	neutral	0,21	6	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,64	low_impact	-3,57	medium_impact	0,36	medium_impact	-0,84	0,57	0,8	51,26	9,33	N	0,4	N	0,89	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4019	4019	C	T	MI.12249	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	713	238	T	I	aCc/aTc	3,21	0,99	0	probably_damaging	1	neutral	0,62	neutral	2,78	neutral	0,62	deleterious	-3,85	medium_impact	2,12	neutral	0,66	neutral	0,45	deleterious	4,08	23,7	0,12	0,4	neutral	0,15	disease	0,67	neutral	0,36	disease	0,51	0	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,68	low_impact	-3,57	medium_impact	0,39	medium_impact	0,66	0,7	0,85	51,26	9,33	N	0,38	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9102	9102	C	G	MI.1225	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	576	192	I	M	atC/atG	3,6	0,99	0	possibly_damaging	0,77	neutral	0,29	neutral	4,3	neutral	-1,74	neutral	-0,28	neutral_impact	0,36	neutral	0,9	neutral	0,73	deleterious	3,23	22,8	0,49	0,65	neutral	0,33	neutral	0,31	neutral	0,27	neutral	0,46	1	neutral	0,82	neutral	0,26	neutral	-3	deleterious	0,57	low_impact	-1,25	medium_impact	0,07	medium_impact	-0,79	0,77	0,9	12,83	11,48	N	0,53	P	0,33	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4019	4019	C	A	MI.12250	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	713	238	T	N	aCc/aAc	3,21	0,99	0	probably_damaging	1	neutral	0,4	neutral	2,7	neutral	-1,81	neutral	-1,8	medium_impact	3,04	neutral	0,62	neutral	0,42	deleterious	3,78	23,4	0,25	0,45	neutral	0,49	disease	0,69	neutral	0,46	neutral	0,48	0	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	0,18	medium_impact	1,47	0,57	0,8	51,26	9,33	P	0,54	P	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4019	4019	C	G	MI.12251	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	713	238	T	S	aCc/aGc	3,21	0,99	0	probably_damaging	1	neutral	0,59	neutral	2,79	neutral	-1,31	neutral	0,27	neutral_impact	0,4	neutral	0,75	neutral	0,86	deleterious	0,85	9,79	0,36	0,5	neutral	0,23	neutral	0,06	neutral	0,24	neutral	0,21	6	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,64	low_impact	-3,57	medium_impact	0,36	medium_impact	-0,84	0,57	0,8	51,26	9,33	P	0,55	P	0,89	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4021	4021	A	C	MI.12252	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	715	239	T	P	Act/Cct	-3	0	0	benign	0,27	neutral	0,12	neutral	2,66	deleterious	-3,64	deleterious	-2,74	high_impact	3,67	neutral	0,61	neutral	0,36	neutral	1,65	14,12	0,04	0,35	disease	0,55	disease	0,82	disease	0,67	disease	0,75	5	neutral	0,86	neutral	0,43	neutral	-2	neutral	0,35	medium_impact	-0,35	medium_impact	-0,21	high_impact	2,02	0,41	0,8	18,87	16,59	N	0,37	N	0,75	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4021	4021	A	G	MI.12253	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	715	239	T	A	Act/Gct	-3	0	0	benign	0	neutral	0,4	neutral	2,81	neutral	0,05	neutral	-0,08	neutral_impact	0,47	neutral	0,86	neutral	0,98	neutral	-0,63	0,11	0,28	0,45	neutral	0,15	neutral	0,12	neutral	0,27	neutral	0,25	5	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,18	medium_impact	-0,78	0,43	0,8	18,87	16,59	N	0,43	N	0,01	polymorphism	1	0,01	rs199771084	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4021	4021	A	T	MI.12254	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	715	239	T	S	Act/Tct	-3	0	0	benign	0,01	neutral	0,69	neutral	2,86	neutral	-0,42	neutral	-0,9	neutral_impact	0,7	neutral	0,82	neutral	0,88	deleterious	0,32	5,86	0,33	0,5	neutral	0,17	neutral	0,31	neutral	0,24	neutral	0,44	1	neutral	0,3	deleterious	0,84	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,47	medium_impact	-0,58	0,6	0,8	18,87	16,59	N	0,32	N	0,14	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4022	4022	C	G	MI.12255	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	716	239	T	S	aCt/aGt	-0,93	0	0	benign	0,01	neutral	0,69	neutral	2,86	neutral	-0,42	neutral	-0,9	neutral_impact	0,7	neutral	0,82	neutral	0,88	deleterious	0,5	7,4	0,33	0,5	neutral	0,17	neutral	0,31	neutral	0,24	neutral	0,44	1	neutral	0,3	deleterious	0,84	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,47	medium_impact	-0,58	0,6	0,8	18,87	16,59	N	0,31	N	0,14	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4022	4022	C	T	MI.12256	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	716	239	T	I	aCt/aTt	-0,93	0	0	benign	0	neutral	0,48	neutral	2,71	neutral	-0,94	neutral	-1,9	medium_impact	2,52	neutral	0,88	neutral	0,94	neutral	0,96	10,4	0,1	0,4	neutral	0,31	disease	0,62	neutral	0,34	neutral	0,46	1	neutral	0,51	deleterious	0,74	neutral	-3	neutral	0,16	high_impact	2,07	medium_impact	0,26	medium_impact	1,01	0,57	0,8	18,87	16,59	N	0,37	N	0,64	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4022	4022	C	A	MI.12257	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	716	239	T	N	aCt/aAt	-0,93	0	0	benign	0	neutral	0,33	neutral	2,68	deleterious	-3,25	deleterious	-2,72	medium_impact	2,87	neutral	0,73	neutral	0,59	neutral	1,72	14,5	0,24	0,45	neutral	0,33	disease	0,66	disease	0,54	disease	0,67	3	neutral	0,67	deleterious	0,67	neutral	-3	neutral	0,18	high_impact	2,07	medium_impact	0,1	medium_impact	1,32	0,54	0,8	18,87	16,59	N	0,42	N	0,56	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4024	4024	A	C	MI.12258	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	718	240	T	P	Aca/Cca	-16,09	0	0,03	possibly_damaging	0,86	neutral	0,1	neutral	2,71	neutral	-2,53	deleterious	-2,57	medium_impact	2,9	neutral	0,77	neutral	0,38	deleterious	1,92	15,7	0,05	0,35	neutral	0,49	disease	0,85	disease	0,62	disease	0,79	6	neutral	0,95	neutral	0,12	NA	0	deleterious	0,67	low_impact	-1,49	medium_impact	-0,26	medium_impact	1,34	0,36	0,8	13,84	16,81	N	0,31	N	0,84	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4024	4024	A	T	MI.12259	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	718	240	T	S	Aca/Tca	-16,09	0	0,03	possibly_damaging	0,52	neutral	0,6	neutral	2,77	neutral	-0,64	neutral	-1,41	low_impact	1,86	neutral	0,78	neutral	0,66	neutral	1,6	13,83	0,38	0,5	neutral	0,19	neutral	0,5	neutral	0,47	disease	0,52	0	neutral	0,46	deleterious	0,54	neutral	-3	neutral	0,25	medium_impact	-0,78	medium_impact	0,37	medium_impact	0,44	0,63	0,8	13,84	16,81	N	0,27	N	0,44	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9102	9102	C	A	MI.1226	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	576	192	I	M	atC/atA	3,6	0,99	0	possibly_damaging	0,77	neutral	0,29	neutral	4,3	neutral	-1,74	neutral	-0,28	neutral_impact	0,36	neutral	0,9	neutral	0,73	deleterious	3,66	23,2	0,49	0,65	neutral	0,33	neutral	0,31	neutral	0,27	neutral	0,46	1	neutral	0,82	neutral	0,26	neutral	-3	deleterious	0,57	low_impact	-1,25	medium_impact	0,07	medium_impact	-0,79	0,77	0,9	12,83	11,48	N	0,53	P	0,33	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4024	4024	A	G	MI.12260	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	718	240	T	A	Aca/Gca	-16,09	0	0,03	benign	0,03	neutral	0,37	neutral	2,81	neutral	0	neutral	-0,87	low_impact	1,58	neutral	0,84	neutral	0,81	neutral	1,59	13,78	0,24	0,45	neutral	0,16	neutral	0,39	neutral	0,48	neutral	0,45	1	neutral	0,61	deleterious	0,67	neutral	-6	neutral	0,1	medium_impact	0,67	medium_impact	0,15	medium_impact	0,19	0,48	0,8	13,84	16,81	N	0,35	N	0,2	polymorphism	1	0,03	rs41504646	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4025	4025	C	A	MI.12261	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	719	240	T	K	aCa/aAa	1,14	0	0,01	possibly_damaging	0,66	neutral	0,14	neutral	2,74	neutral	-1,47	neutral	-2,49	medium_impact	2,9	neutral	0,65	neutral	0,43	deleterious	2,63	20,4	0,06	0,35	neutral	0,21	disease	0,79	disease	0,59	disease	0,75	5	neutral	0,87	neutral	0,24	NA	0	deleterious	0,52	low_impact	-1,02	medium_impact	-0,17	medium_impact	1,34	0,49	0,8	13,84	16,81	N	0,41	N	0,78	disease_causing_automatic	0	0,2	rs397515509	Pathogenic	Leber's_optic_atrophy	RCV000055709.1	MedGen:OMIM:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	4025	4025	C	T	MI.12262	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	719	240	T	M	aCa/aTa	1,14	0	0,01	benign	0,14	neutral	0,91	neutral	2,75	neutral	-1,15	neutral	0,09	low_impact	1,07	neutral	0,83	neutral	0,78	deleterious	2,07	16,64	0,1	0,4	neutral	0,32	disease	0,54	neutral	0,3	neutral	0,45	1	neutral	0,06	deleterious	0,89	neutral	-6	neutral	0,15	medium_impact	-0,01	medium_impact	0,84	medium_impact	-0,25	0,59	0,8	13,84	16,81	N	0,24	N	0,05	disease_causing_automatic	0	0,02	rs397515509	Pathogenic	Leber's_optic_atrophy	RCV000055709.1	MedGen:OMIM:SNOMED_CT	.	.	CPD	2,97	.	.	.	.	.	.
chrM	4027	4027	A	C	MI.12263	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	721	241	I	L	Atc/Ctc	-6,44	0	0	benign	0,04	neutral	1	neutral	3,27	neutral	2,42	neutral	1,27	neutral_impact	-1,01	neutral	0,72	neutral	0,94	neutral	1,1	11,24	0,24	0,45	neutral	0,18	neutral	0,16	neutral	0,28	neutral	0,24	5	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,11	medium_impact	0,55	high_impact	1,96	low_impact	-2,07	0,57	0,8	27,04	42,75	N	0,36	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4027	4027	A	G	MI.12264	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	721	241	I	V	Atc/Gtc	-6,44	0	0	possibly_damaging	0,64	neutral	0,47	neutral	2,72	neutral	0,2	neutral	-0,84	low_impact	1,68	neutral	0,87	neutral	0,9	deleterious	3,03	22,3	0,35	0,5	neutral	0,16	neutral	0,33	neutral	0,36	neutral	0,44	1	neutral	0,63	neutral	0,42	neutral	-3	neutral	0,36	medium_impact	-0,99	medium_impact	0,25	medium_impact	0,28	0,44	0,8	27,04	42,75	N	0,34	N	0,08	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4027	4027	A	T	MI.12265	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	721	241	I	F	Atc/Ttc	-6,44	0	0	possibly_damaging	0,89	neutral	0,75	neutral	2,64	neutral	-0,82	neutral	-2,09	low_impact	1,26	neutral	0,82	neutral	0,55	deleterious	3,98	23,6	0,18	0,45	neutral	0,33	disease	0,68	neutral	0,37	disease	0,52	0	neutral	0,87	neutral	0,43	neutral	-3	deleterious	0,67	low_impact	-1,6	medium_impact	0,54	medium_impact	-0,09	0,56	0,8	27,04	42,75	N	0,26	N	0,69	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4028	4028	T	A	MI.12266	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	722	241	I	N	aTc/aAc	-1,16	0	0	probably_damaging	0,98	neutral	0,52	neutral	2,6	deleterious	-3,84	deleterious	-4,81	medium_impact	2,88	neutral	0,69	neutral	0,53	deleterious	4,7	24,6	0,07	0,35	disease	0,69	disease	0,8	disease	0,59	disease	0,75	5	neutral	0,98	neutral	0,27	deleterious	1	deleterious	0,82	low_impact	-2,34	medium_impact	0,29	medium_impact	1,33	0,47	0,8	27,04	42,75	N	0,27	N	0,92	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4028	4028	T	C	MI.12267	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	722	241	I	T	aTc/aCc	-1,16	0	0	probably_damaging	0,91	neutral	0,66	neutral	2,63	neutral	-2,17	deleterious	-2,96	medium_impact	2,67	neutral	0,68	neutral	0,49	deleterious	3,52	23,1	0,06	0,35	neutral	0,44	disease	0,52	disease	0,53	disease	0,61	2	neutral	0,89	neutral	0,38	deleterious	1	deleterious	0,67	low_impact	-1,69	medium_impact	0,44	medium_impact	1,14	0,31	0,8	27,04	42,75	N	0,26	N	0,83	polymorphism	1	0,19	.	.	.	.	.	MNGIE fibroblasts	.	.	.	.	.	.	.	.	.
chrM	4028	4028	T	G	MI.12268	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	722	241	I	S	aTc/aGc	-1,16	0	0	probably_damaging	0,96	neutral	0,64	neutral	2,62	neutral	-2,61	deleterious	-3,88	medium_impact	2,53	neutral	0,7	neutral	0,55	deleterious	4,32	24	0,03	0,35	disease	0,52	disease	0,73	disease	0,56	disease	0,7	4	neutral	0,95	neutral	0,34	deleterious	1	deleterious	0,76	low_impact	-2,05	medium_impact	0,42	medium_impact	1,02	0,31	0,8	27,04	42,75	N	0,23	N	0,87	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4029	4029	C	A	MI.12269	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	723	241	I	M	atC/atA	7,34	0,95	0	probably_damaging	0,92	neutral	0,5	neutral	2,68	neutral	-0,95	neutral	-0,27	neutral_impact	0,43	neutral	0,79	neutral	0,9	deleterious	2,81	21,4	0,25	0,45	neutral	0,23	neutral	0,38	neutral	0,32	neutral	0,45	1	neutral	0,91	neutral	0,29	neutral	-2	deleterious	0,62	low_impact	-1,75	medium_impact	0,28	medium_impact	-0,81	0,53	0,8	27,04	42,75	N	0,51	P	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9103	9103	T	C	MI.1227	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	577	193	F	L	Ttc/Ctc	-8,66	0	0	benign	0,01	neutral	1	neutral	4,6	neutral	-0,5	deleterious	-2,5	neutral_impact	-0,32	neutral	0,95	neutral	0,85	deleterious	0,84	9,74	0,44	0,65	disease	0,64	neutral	0,28	neutral	0,28	disease	0,57	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,17	medium_impact	1,14	high_impact	1,98	low_impact	-1,37	0,64	0,9	25,22	21,86	N	0,23	N	0,33	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4029	4029	C	G	MI.12270	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	723	241	I	M	atC/atG	7,34	0,95	0	probably_damaging	0,92	neutral	0,5	neutral	2,68	neutral	-0,95	neutral	-0,27	neutral_impact	0,43	neutral	0,79	neutral	0,9	deleterious	2,4	18,79	0,25	0,45	neutral	0,23	neutral	0,38	neutral	0,32	neutral	0,45	1	neutral	0,91	neutral	0,29	neutral	-2	deleterious	0,62	low_impact	-1,75	medium_impact	0,28	medium_impact	-0,81	0,53	0,8	27,04	42,75	N	0,51	P	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4030	4030	T	C	MI.12271	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	724	242	F	L	Ttc/Ctc	-5,07	0	0	probably_damaging	1	neutral	0,96	neutral	2,22	deleterious	-4,95	deleterious	-5,55	medium_impact	3,26	neutral	0,71	neutral	0,59	deleterious	4,13	23,8	0,06	0,35	neutral	0,27	disease	0,77	disease	0,67	disease	0,68	4	deleterious	1	deleterious	0,48	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	1,05	medium_impact	1,66	0,41	0,8	59,43	10,58	N	0,34	N	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4030	4030	T	A	MI.12272	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	724	242	F	I	Ttc/Atc	-5,07	0	0	probably_damaging	1	neutral	0,51	neutral	2,18	deleterious	-6,06	deleterious	-5,55	high_impact	4,38	neutral	0,7	neutral	0,6	deleterious	4,46	24,2	0,07	0,35	neutral	0,39	disease	0,76	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	0,29	high_impact	2,64	0,41	0,8	59,43	10,58	N	0,47	N	0,97	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4030	4030	T	G	MI.12273	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	724	242	F	V	Ttc/Gtc	-5,07	0	0	probably_damaging	1	neutral	0,52	neutral	2,19	deleterious	-5,4	deleterious	-6,48	high_impact	4,38	neutral	0,62	neutral	0,51	deleterious	4,14	23,8	0,06	0,35	neutral	0,35	disease	0,8	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	0,29	high_impact	2,64	0,32	0,8	59,43	10,58	N	0,44	N	0,98	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4031	4031	T	A	MI.12274	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	725	242	F	Y	tTc/tAc	5,5	1	0	probably_damaging	1	neutral	0,67	neutral	2,44	deleterious	-3,66	deleterious	-2,78	medium_impact	3,12	neutral	0,69	neutral	0,46	deleterious	4,33	24	0,1	0,4	neutral	0,42	disease	0,64	disease	0,7	disease	0,5	0	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,45	medium_impact	1,54	0,49	0,8	59,43	10,58	P	0,56	P	0,88	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4031	4031	T	C	MI.12275	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	725	242	F	S	tTc/tCc	5,5	1	0	probably_damaging	1	neutral	0,66	neutral	2,19	deleterious	-6,83	deleterious	-7,4	high_impact	4,04	neutral	0,6	neutral	0,63	deleterious	4,34	24	0,04	0,35	neutral	0,49	disease	0,82	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,44	high_impact	2,34	0,29	0,8	59,43	10,58	P	0,58	P	0,98	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4031	4031	T	G	MI.12276	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	725	242	F	C	tTc/tGc	5,5	1	0	probably_damaging	1	neutral	0,14	neutral	2,14	deleterious	-8,38	deleterious	-7,41	high_impact	4,38	neutral	0,66	neutral	0,49	deleterious	4,19	23,8	0,04	0,35	disease	0,55	disease	0,84	disease	0,75	disease	0,78	6	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	-0,17	high_impact	2,64	0,22	0,8	59,43	10,58	P	0,6	P	1	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4032	4032	C	G	MI.12277	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	726	242	F	L	ttC/ttG	7,34	1	0	probably_damaging	1	neutral	0,96	neutral	2,22	deleterious	-4,95	deleterious	-5,55	medium_impact	3,26	neutral	0,71	neutral	0,59	deleterious	4,45	24,2	0,06	0,35	neutral	0,27	disease	0,77	disease	0,67	disease	0,68	4	deleterious	1	deleterious	0,48	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	1,05	medium_impact	1,66	0,41	0,8	59,43	10,58	N	0,51	P	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4032	4032	C	A	MI.12278	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	726	242	F	L	ttC/ttA	7,34	1	0	probably_damaging	1	neutral	0,96	neutral	2,22	deleterious	-4,95	deleterious	-5,55	medium_impact	3,26	neutral	0,71	neutral	0,59	deleterious	4,77	24,7	0,06	0,35	neutral	0,27	disease	0,77	disease	0,67	disease	0,68	4	deleterious	1	deleterious	0,48	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	1,05	medium_impact	1,66	0,41	0,8	59,43	10,58	N	0,51	P	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4033	4033	C	A	MI.12279	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	727	243	L	M	Cta/Ata	-2,31	0	0	benign	0,4	neutral	0,38	neutral	2,26	deleterious	-3,83	neutral	-1,09	low_impact	1,67	neutral	0,87	neutral	0,9	deleterious	2,51	19,56	0,31	0,45	disease	0,54	neutral	0,23	neutral	0,4	neutral	0,48	0	neutral	0,56	deleterious	0,49	neutral	-6	neutral	0,29	medium_impact	-0,59	medium_impact	0,16	medium_impact	0,27	0,63	0,8	23,27	13,76	N	0,45	N	0,45	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9103	9103	T	G	MI.1228	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	577	193	F	V	Ttc/Gtc	-8,66	0	0	benign	0,22	neutral	0,5	neutral	4,41	neutral	-1,06	deleterious	-3,13	low_impact	1,47	neutral	0,88	neutral	0,7	neutral	1,1	11,22	0,25	0,65	disease	0,65	neutral	0,44	neutral	0,4	disease	0,61	2	neutral	0,4	deleterious	0,64	neutral	-6	neutral	0,31	medium_impact	-0,23	medium_impact	0,29	medium_impact	0,16	0,54	0,9	25,22	21,86	N	0,29	N	0,85	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4033	4033	C	G	MI.12280	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	727	243	L	V	Cta/Gta	-2,31	0	0	possibly_damaging	0,64	neutral	0,32	neutral	2,32	neutral	-2,63	neutral	-2,23	medium_impact	3,01	neutral	0,72	damaging	0,17	deleterious	3,46	23	0,24	0,45	neutral	0,33	neutral	0,42	disease	0,67	neutral	0,48	0	neutral	0,72	neutral	0,34	NA	0	deleterious	0,55	medium_impact	-0,99	medium_impact	0,09	medium_impact	1,44	0,58	0,8	23,27	13,76	N	0,35	N	0,34	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4034	4034	T	A	MI.12281	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	728	243	L	Q	cTa/cAa	-3,46	0	0	probably_damaging	0,96	neutral	0,07	neutral	2,22	deleterious	-5,24	deleterious	-4,78	high_impact	4,11	neutral	0,72	damaging	0,16	deleterious	4,14	23,8	0,04	0,35	disease	0,77	disease	0,73	disease	0,67	disease	0,69	4	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,81	low_impact	-2,05	medium_impact	-0,35	high_impact	2,4	0,3	0,8	23,27	13,76	N	0,38	N	0,94	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4034	4034	T	G	MI.12282	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	728	243	L	R	cTa/cGa	-3,46	0	0	probably_damaging	0,96	neutral	0,09	neutral	2,22	deleterious	-5,11	deleterious	-4,92	high_impact	3,76	neutral	0,63	damaging	0,12	deleterious	4,24	23,9	0,03	0,35	disease	0,77	disease	0,83	disease	0,77	disease	0,79	6	deleterious	0,98	neutral	0,07	deleterious	2	deleterious	0,84	low_impact	-2,05	medium_impact	-0,29	high_impact	2,1	0,28	0,8	23,27	13,76	N	0,39	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4034	4034	T	C	MI.12283	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	728	243	L	P	cTa/cCa	-3,46	0	0	probably_damaging	0,97	neutral	0,05	neutral	2,23	deleterious	-5,14	deleterious	-5,14	high_impact	3,76	neutral	0,64	damaging	0,13	deleterious	3,98	23,6	0,03	0,35	disease	0,52	disease	0,77	disease	0,77	disease	0,76	5	deleterious	0,99	neutral	0,04	deleterious	2	deleterious	0,82	low_impact	-2,17	medium_impact	-0,44	high_impact	2,1	0,28	0,8	23,27	13,76	N	0,38	N	0,94	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4036	4036	G	C	MI.12284	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	730	244	G	R	Gga/Cga	-0,7	0,33	0	probably_damaging	0,93	neutral	0,25	neutral	2,36	deleterious	-4,05	deleterious	-5,24	high_impact	3,96	neutral	0,68	damaging	0,25	deleterious	3,96	23,6	0,02	0,35	neutral	0,45	disease	0,82	disease	0,78	disease	0,75	5	neutral	0,95	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-1,81	medium_impact	0,01	high_impact	2,27	0,45	0,8	22,64	17,2	N	0,46	N	0,99	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4036	4036	G	T	MI.12285	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	730	244	G	W	Gga/Tga	-0,7	0,33	0	probably_damaging	0,98	neutral	0,14	neutral	2,31	deleterious	-6,59	deleterious	-5,92	high_impact	3,77	neutral	0,73	damaging	0,25	deleterious	4,48	24,2	0,05	0,35	disease	0,85	disease	0,82	disease	0,74	disease	0,8	6	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,85	low_impact	-2,34	medium_impact	-0,17	high_impact	2,1	0,12	0,8	22,64	17,2	N	0,38	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4037	4037	G	C	MI.12286	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	731	244	G	A	gGa/gCa	4,81	1	0	benign	0,05	neutral	0,46	neutral	2,41	deleterious	-3,39	deleterious	-3,87	medium_impact	2,87	neutral	0,83	neutral	0,64	deleterious	2,1	16,85	0,09	0,35	neutral	0,36	neutral	0,46	disease	0,61	neutral	0,43	1	neutral	0,5	deleterious	0,71	neutral	-3	neutral	0,22	medium_impact	0,45	medium_impact	0,24	medium_impact	1,32	0,33	0,8	22,64	17,2	P	0,59	P	0,8	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4037	4037	G	A	MI.12287	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	731	244	G	E	gGa/gAa	4,81	1	0	possibly_damaging	0,75	neutral	0,2	neutral	2,41	deleterious	-3,37	deleterious	-5,16	high_impact	3,77	neutral	0,72	neutral	0,33	deleterious	3,97	23,6	0,02	0,35	neutral	0,37	disease	0,81	disease	0,78	disease	0,74	5	neutral	0,86	neutral	0,23	deleterious	1	deleterious	0,73	low_impact	-1,2	medium_impact	-0,06	high_impact	2,1	0,2	0,8	22,64	17,2	P	0,64	P	0,97	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4037	4037	G	T	MI.12288	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	731	244	G	V	gGa/gTa	4,81	1	0	possibly_damaging	0,75	neutral	0,63	neutral	2,35	deleterious	-4,11	deleterious	-6,25	high_impact	3,77	neutral	0,72	neutral	0,36	deleterious	3,83	23,4	0,03	0,35	neutral	0,36	disease	0,74	disease	0,69	disease	0,68	4	neutral	0,71	neutral	0,44	deleterious	1	deleterious	0,7	low_impact	-1,2	medium_impact	0,4	high_impact	2,1	0,16	0,8	22,64	17,2	N	0,53	P	0,97	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4039	4039	A	C	MI.12289	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	733	245	T	P	Aca/Cca	-5,52	0	0	possibly_damaging	0,81	neutral	0,16	neutral	2,73	neutral	-1,39	neutral	0,86	neutral_impact	-0,97	neutral	0,86	neutral	0,98	neutral	1,73	14,58	0,07	0,35	neutral	0,3	neutral	0,35	neutral	0,19	neutral	0,44	1	neutral	0,91	neutral	0,18	neutral	-3	deleterious	0,63	low_impact	-1,34	medium_impact	-0,13	low_impact	-2,04	0,37	0,8	30,82	36,57	N	0,49	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9103	9103	T	A	MI.1229	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	577	193	F	I	Ttc/Atc	-8,66	0	0	benign	0,14	neutral	0,59	neutral	4,46	neutral	-1,59	deleterious	-2,62	low_impact	1,07	neutral	0,86	neutral	0,61	neutral	1,41	12,83	0,24	0,65	disease	0,72	neutral	0,32	neutral	0,33	disease	0,64	3	neutral	0,3	deleterious	0,73	neutral	-6	neutral	0,29	medium_impact	-0,01	medium_impact	0,38	medium_impact	-0,18	0,54	0,9	25,22	21,86	N	0,24	N	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4039	4039	A	T	MI.12290	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	733	245	T	S	Aca/Tca	-5,52	0	0	benign	0,06	neutral	0,39	neutral	2,86	neutral	0,55	neutral	0,29	neutral_impact	-1,08	neutral	0,83	neutral	0,99	neutral	1,62	13,95	0,32	0,5	neutral	0,21	neutral	0,13	neutral	0,2	neutral	0,26	5	neutral	0,57	deleterious	0,67	neutral	-6	neutral	0,13	medium_impact	0,37	medium_impact	0,17	low_impact	-2,13	0,56	0,8	30,82	36,57	N	0,48	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4039	4039	A	G	MI.12291	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	733	245	T	A	Aca/Gca	-5,52	0	0	benign	0,02	neutral	0,57	neutral	2,85	neutral	0,47	neutral	0,53	neutral_impact	-0,57	neutral	0,79	neutral	0,95	deleterious	0,86	9,83	0,25	0,45	neutral	0,14	neutral	0,06	neutral	0,25	neutral	0,23	5	neutral	0,4	deleterious	0,78	neutral	-6	neutral	0,1	medium_impact	0,84	medium_impact	0,34	low_impact	-1,69	0,32	0,8	30,82	36,57	N	0,35	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4040	4040	C	T	MI.12292	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	734	245	T	M	aCa/aTa	-3,69	0	0	benign	0,32	neutral	0,38	neutral	2,7	neutral	-2,57	neutral	-1,61	low_impact	1	neutral	0,76	neutral	0,74	deleterious	4,04	23,7	0,14	0,4	neutral	0,28	neutral	0,37	neutral	0,45	neutral	0,45	1	neutral	0,54	deleterious	0,53	neutral	-6	neutral	0,18	medium_impact	-0,44	medium_impact	0,16	medium_impact	-0,32	0,61	0,8	30,82	36,57	N	0,35	N	0,64	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4040	4040	C	A	MI.12293	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	734	245	T	K	aCa/aAa	-3,69	0	0	possibly_damaging	0,56	neutral	0,21	neutral	2,74	neutral	-1,21	neutral	-1,34	low_impact	1,43	neutral	0,66	neutral	0,52	deleterious	4,6	24,4	0,08	0,35	neutral	0,23	disease	0,55	disease	0,56	disease	0,68	4	neutral	0,78	neutral	0,33	neutral	-3	deleterious	0,44	medium_impact	-0,85	medium_impact	-0,05	medium_impact	0,06	0,35	0,8	30,82	36,57	N	0,38	N	0,47	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4042	4042	A	G	MI.12294	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	736	246	T	A	Aca/Gca	-1,62	0	0	benign	0,04	neutral	0,4	neutral	2,82	neutral	0,62	neutral	-0,7	low_impact	1,72	neutral	0,85	neutral	0,82	neutral	1,74	14,62	0,21	0,45	neutral	0,15	neutral	0,22	neutral	0,39	neutral	0,38	2	neutral	0,57	deleterious	0,68	neutral	-6	neutral	0,13	medium_impact	0,55	medium_impact	0,18	medium_impact	0,31	0,29	0,8	30,82	33,51	N	0,35	N	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4042	4042	A	T	MI.12295	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	736	246	T	S	Aca/Tca	-1,62	0	0	benign	0,01	neutral	0,49	neutral	2,83	neutral	0,33	neutral	0,33	neutral_impact	-0,57	neutral	0,89	neutral	0,97	neutral	0,98	10,56	0,31	0,45	neutral	0,13	neutral	0,06	neutral	0,26	neutral	0,23	5	neutral	0,5	deleterious	0,74	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,27	low_impact	-1,69	0,7	0,85	30,82	33,51	N	0,44	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4042	4042	A	C	MI.12296	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	736	246	T	P	Aca/Cca	-1,62	0	0	benign	0	neutral	0,15	neutral	2,76	neutral	0,34	neutral	-1,31	low_impact	1,13	neutral	0,88	neutral	0,79	deleterious	2,13	17,04	0,07	0,35	neutral	0,4	disease	0,66	neutral	0,4	neutral	0,49	0	neutral	0,85	deleterious	0,58	neutral	-6	neutral	0,22	high_impact	2,07	medium_impact	-0,15	medium_impact	-0,2	0,42	0,8	30,82	33,51	N	0,39	N	0,12	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4043	4043	C	T	MI.12297	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	737	246	T	M	aCa/aTa	-0,7	0	0	benign	0,36	neutral	0,31	neutral	2,75	neutral	-1,14	neutral	-1,6	low_impact	1,32	neutral	0,87	neutral	0,86	deleterious	2,68	20,7	0,16	0,45	neutral	0,27	neutral	0,36	neutral	0,34	neutral	0,45	1	neutral	0,63	deleterious	0,48	neutral	-6	neutral	0,4	medium_impact	-0,52	medium_impact	0,08	medium_impact	-0,04	0,65	0,8	30,82	33,51	N	0,42	N	0,04	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4043	4043	C	A	MI.12298	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	737	246	T	K	aCa/aAa	-0,7	0	0	benign	0,11	neutral	0,19	neutral	2,81	neutral	-0,3	neutral	-1,74	low_impact	1,82	neutral	0,69	neutral	0,51	deleterious	3,22	22,7	0,1	0,4	neutral	0,22	disease	0,57	neutral	0,49	disease	0,52	0	neutral	0,78	deleterious	0,54	neutral	-6	neutral	0,22	medium_impact	0,1	medium_impact	-0,08	medium_impact	0,4	0,38	0,8	30,82	33,51	N	0,44	N	0,51	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4045	4045	T	C	MI.12299	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	739	247	Y	H	Tat/Cat	-7,13	0	0	benign	0,01	neutral	0,35	neutral	2,83	neutral	-0,56	neutral	0,68	neutral_impact	-0,6	neutral	0,73	neutral	0,97	neutral	-0,97	0,02	0,15	0,4	neutral	0,12	neutral	0,12	neutral	0,29	neutral	0,27	5	neutral	0,64	deleterious	0,67	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	0,12	low_impact	-1,71	0,28	0,8	31,76	37,78	N	0,43	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8584	8584	G	C	MI.123	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	58	20	A	P	Gca/Cca	-5,89	0	0,17	possibly_damaging	0,68	neutral	0,2	neutral	4,56	neutral	-2,79	neutral	-2,31	low_impact	0,9	neutral	0,81	neutral	0,38	deleterious	3,43	23	0,13	0,65	disease	0,65	disease	0,79	disease	0,6	disease	0,78	6	neutral	0,83	neutral	0,26	neutral	-3	deleterious	0,73	low_impact	-1,07	medium_impact	-0,05	medium_impact	-0,33	0,71	0,9	24,78	23,03	N	0,24	N	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9104	9104	T	G	MI.1230	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	578	193	F	C	tTc/tGc	-1,26	0	0	probably_damaging	0,91	neutral	0,08	neutral	4,28	deleterious	-4,49	deleterious	-4,29	medium_impact	2,68	neutral	0,77	neutral	0,45	deleterious	4,1	23,7	0,23	0,65	disease	0,89	disease	0,55	neutral	0,44	disease	0,59	2	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,72	low_impact	-1,71	medium_impact	-0,31	medium_impact	1,2	0,33	0,9	25,22	21,86	N	0,35	N	0,83	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4045	4045	T	G	MI.12300	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	739	247	Y	D	Tat/Gat	-7,13	0	0	possibly_damaging	0,47	neutral	0,09	neutral	2,84	neutral	-2,3	deleterious	-2,82	low_impact	1,2	neutral	0,87	neutral	0,58	deleterious	2,22	17,67	0,08	0,35	neutral	0,12	disease	0,61	disease	0,52	disease	0,59	2	neutral	0,9	neutral	0,31	neutral	-3	neutral	0,41	medium_impact	-0,7	medium_impact	-0,29	medium_impact	-0,14	0,21	0,8	31,76	37,78	N	0,4	N	0,62	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4045	4045	T	A	MI.12301	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	739	247	Y	N	Tat/Aat	-7,13	0	0	benign	0,38	neutral	0,18	neutral	2,85	neutral	-0,83	neutral	-1,54	neutral_impact	0,42	neutral	0,86	neutral	0,96	deleterious	0,86	9,83	0,15	0,4	neutral	0,12	neutral	0,42	neutral	0,35	neutral	0,43	1	neutral	0,79	neutral	0,4	neutral	-6	neutral	0,23	medium_impact	-0,55	medium_impact	-0,09	medium_impact	-0,82	0,26	0,8	31,76	37,78	N	0,38	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4046	4046	A	C	MI.12302	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	740	247	Y	S	tAt/tCt	-1,62	0	0	benign	0,34	neutral	0,38	neutral	2,89	neutral	-0,68	neutral	-2,02	neutral_impact	-0,16	neutral	0,81	neutral	0,8	deleterious	0,7	8,82	0,1	0,4	neutral	0,14	neutral	0,34	neutral	0,35	neutral	0,43	1	neutral	0,55	deleterious	0,52	neutral	-6	neutral	0,26	medium_impact	-0,48	medium_impact	0,16	low_impact	-1,33	0,24	0,8	31,76	37,78	N	0,29	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4046	4046	A	G	MI.12303	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	740	247	Y	C	tAt/tGt	-1,62	0	0	benign	0,02	neutral	0,11	neutral	2,78	neutral	-2,82	deleterious	-2,97	low_impact	1,9	neutral	0,9	neutral	0,76	deleterious	2,14	17,13	0,06	0,35	disease	0,5	disease	0,64	neutral	0,38	neutral	0,5	0	neutral	0,89	deleterious	0,55	neutral	-6	neutral	0,18	medium_impact	0,84	medium_impact	-0,23	medium_impact	0,47	0,05	0,8	31,76	37,78	N	0,43	N	0,55	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4046	4046	A	T	MI.12304	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	740	247	Y	F	tAt/tTt	-1,62	0	0	benign	0,01	neutral	0,76	neutral	2,83	neutral	0,2	neutral	-1,26	low_impact	0,88	neutral	0,85	neutral	0,93	deleterious	-0,02	2,35	0,22	0,45	neutral	0,27	neutral	0,24	neutral	0,27	neutral	0,43	2	neutral	0,21	deleterious	0,88	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,56	medium_impact	-0,42	0,4	0,8	31,76	37,78	N	0,32	N	0,06	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4048	4048	G	T	MI.12305	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	742	248	D	Y	Gac/Tac	-4,38	0	0,1	benign	0,23	neutral	0,98	neutral	2,75	neutral	-2,86	neutral	-0,16	neutral_impact	0,18	neutral	0,88	neutral	0,87	neutral	-0,42	0,35	0,08	0,35	neutral	0,39	neutral	0,35	neutral	0,26	neutral	0,46	1	neutral	0,18	deleterious	0,88	neutral	-6	neutral	0,32	medium_impact	-0,26	medium_impact	1,22	low_impact	-1,03	0,14	0,8	25,79	23,77	N	0,25	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4048	4048	G	A	MI.12306	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	742	248	D	N	Gac/Aac	-4,38	0	0,1	benign	0	neutral	0,37	neutral	2,81	neutral	-0,4	neutral	1,51	neutral_impact	-1,12	neutral	0,83	neutral	0,94	deleterious	0,26	5,29	0,38	0,5	neutral	0,13	neutral	0,09	neutral	0,22	neutral	0,29	4	neutral	0,63	deleterious	0,69	neutral	-6	neutral	0,07	high_impact	2,07	medium_impact	0,15	low_impact	-2,17	0,62	0,8	25,79	23,77	N	0,34	N	0,02	polymorphism	1	0,01	rs201629275	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4048	4048	G	C	MI.12307	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	742	248	D	H	Gac/Cac	-4,38	0	0,1	benign	0,26	neutral	0,51	neutral	2,76	neutral	-2,02	neutral	0,36	low_impact	0,84	neutral	0,8	neutral	0,78	deleterious	-0,01	2,5	0,12	0,4	neutral	0,25	neutral	0,21	neutral	0,3	neutral	0,36	3	neutral	0,39	deleterious	0,63	neutral	-6	neutral	0,18	medium_impact	-0,32	medium_impact	0,29	medium_impact	-0,46	0,32	0,8	25,79	23,77	N	0,31	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4049	4049	A	T	MI.12308	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	743	248	D	V	gAc/gTc	-0,47	0	0	benign	0,04	neutral	0,57	neutral	2,8	neutral	-1,58	neutral	0,07	neutral_impact	0,34	neutral	0,83	neutral	0,79	deleterious	0,11	3,7	0,08	0,35	neutral	0,29	neutral	0,32	neutral	0,39	neutral	0,44	1	neutral	0,38	deleterious	0,77	neutral	-6	neutral	0,11	medium_impact	0,55	medium_impact	0,34	medium_impact	-0,89	0,07	0,8	25,79	23,77	N	0,29	N	0,2	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4049	4049	A	C	MI.12309	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	743	248	D	A	gAc/gCc	-0,47	0	0	benign	0,01	neutral	0,49	neutral	2,85	neutral	-0,51	neutral	-0,32	neutral_impact	0,18	neutral	0,83	neutral	0,81	deleterious	-0,03	2,3	0,12	0,4	neutral	0,16	neutral	0,2	neutral	0,39	neutral	0,35	3	neutral	0,5	deleterious	0,74	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,27	low_impact	-1,03	0,33	0,8	25,79	23,77	N	0,33	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9104	9104	T	A	MI.1231	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	578	193	F	Y	tTc/tAc	-1,26	0	0	benign	0,43	neutral	0,3	neutral	4,3	deleterious	-3,33	neutral	-1,82	medium_impact	2,06	neutral	0,87	neutral	0,55	neutral	1,44	13,02	0,26	0,65	disease	0,78	neutral	0,35	neutral	0,46	disease	0,64	3	neutral	0,65	neutral	0,44	neutral	-3	deleterious	0,53	medium_impact	-0,64	medium_impact	0,08	medium_impact	0,67	0,54	0,9	25,22	21,86	N	0,41	N	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4049	4049	A	G	MI.12310	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	743	248	D	G	gAc/gGc	-0,47	0	0	benign	0,02	neutral	0,53	neutral	2,78	neutral	-0,07	neutral	-0,68	neutral_impact	-0,63	neutral	0,69	neutral	0,63	deleterious	0,63	8,37	0,13	0,4	neutral	0,18	neutral	0,28	neutral	0,44	neutral	0,42	2	neutral	0,45	deleterious	0,76	neutral	-6	neutral	0,09	medium_impact	0,84	medium_impact	0,3	low_impact	-1,74	0,32	0,8	25,79	23,77	N	0,32	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4050	4050	C	A	MI.12311	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	744	248	D	E	gaC/gaA	-2,31	0	0	benign	0,02	neutral	0,26	neutral	2,87	neutral	0,02	neutral	-0,08	low_impact	0,84	neutral	0,74	neutral	0,65	neutral	0,92	10,19	0,18	0,45	neutral	0,11	neutral	0,26	neutral	0,33	neutral	0,41	2	neutral	0,73	deleterious	0,62	neutral	-6	neutral	0,08	medium_impact	0,84	medium_impact	0,02	medium_impact	-0,46	0,61	0,8	25,79	23,77	N	0,45	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4050	4050	C	G	MI.12312	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	744	248	D	E	gaC/gaG	-2,31	0	0	benign	0,02	neutral	0,26	neutral	2,87	neutral	0,02	neutral	-0,08	low_impact	0,84	neutral	0,74	neutral	0,65	deleterious	0,58	8,04	0,18	0,45	neutral	0,11	neutral	0,26	neutral	0,33	neutral	0,41	2	neutral	0,73	deleterious	0,62	neutral	-6	neutral	0,08	medium_impact	0,84	medium_impact	0,02	medium_impact	-0,46	0,61	0,8	25,79	23,77	N	0,45	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4051	4051	G	C	MI.12313	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	745	249	A	P	Gca/Cca	-3,69	0	0	benign	0	neutral	0,22	neutral	2,73	neutral	-1,55	neutral	2,06	neutral_impact	-2,08	neutral	0,81	neutral	0,95	neutral	-0,65	0,1	0,09	0,35	neutral	0,16	neutral	0,18	neutral	0,3	neutral	0,33	3	neutral	0,78	deleterious	0,61	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	-0,03	low_impact	-3	0,49	0,8	30,82	42,25	N	0,32	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4051	4051	G	T	MI.12314	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	745	249	A	S	Gca/Tca	-3,69	0	0	benign	0	neutral	0,44	neutral	2,78	neutral	-0,32	neutral	0,44	neutral_impact	-0,08	neutral	0,81	neutral	0,95	deleterious	0,58	8,05	0,27	0,45	neutral	0,25	neutral	0,16	neutral	0,25	neutral	0,29	4	neutral	0,56	deleterious	0,72	neutral	-6	neutral	0,13	high_impact	2,07	medium_impact	0,22	low_impact	-1,26	0,36	0,8	30,82	42,25	N	0,41	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4051	4051	G	A	MI.12315	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	745	249	A	T	Gca/Aca	-3,69	0	0	benign	0	neutral	0,4	neutral	2,77	neutral	-0,49	neutral	0,35	neutral_impact	-0,72	neutral	0,9	neutral	0,85	neutral	1,04	10,87	0,24	0,45	neutral	0,24	neutral	0,17	neutral	0,38	neutral	0,31	4	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,18	low_impact	-1,82	0,7	0,85	30,82	42,25	N	0,39	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4052	4052	C	T	MI.12316	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	746	249	A	V	gCa/gTa	-1,16	0	0	benign	0	neutral	0,51	neutral	2,85	neutral	0,43	neutral	-0,62	neutral_impact	0,24	neutral	0,86	neutral	0,83	neutral	1,43	12,97	0,18	0,45	neutral	0,15	neutral	0,3	neutral	0,4	neutral	0,44	1	neutral	0,49	deleterious	0,76	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,29	medium_impact	-0,98	0,7	0,85	30,82	42,25	N	0,31	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4052	4052	C	A	MI.12317	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	746	249	A	E	gCa/gAa	-1,16	0	0	benign	0,04	neutral	0,27	neutral	2,77	neutral	-0,6	neutral	-0,07	low_impact	1,09	neutral	0,87	neutral	0,58	neutral	1,52	13,43	0,06	0,35	neutral	0,3	disease	0,57	neutral	0,49	neutral	0,49	0	neutral	0,71	deleterious	0,62	neutral	-6	neutral	0,18	medium_impact	0,55	medium_impact	0,03	medium_impact	-0,24	0,31	0,8	30,82	42,25	N	0,39	N	0,16	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4052	4052	C	G	MI.12318	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	746	249	A	G	gCa/gGa	-1,16	0	0	benign	0,04	neutral	0,39	neutral	2,73	neutral	-1,57	neutral	-0,85	neutral_impact	0,34	neutral	0,8	neutral	0,7	neutral	0,96	10,45	0,29	0,45	neutral	0,4	neutral	0,31	neutral	0,38	neutral	0,45	1	neutral	0,58	deleterious	0,68	neutral	-6	neutral	0,16	medium_impact	0,55	medium_impact	0,17	medium_impact	-0,89	0,52	0,8	30,82	42,25	N	0,33	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4054	4054	C	G	MI.12319	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	748	250	L	V	Ctc/Gtc	-6,44	0	0	benign	0,02	neutral	0,51	neutral	2,74	neutral	-1,07	neutral	-0,55	low_impact	1,62	neutral	0,88	neutral	0,78	neutral	-0,2	1,11	0,31	0,45	neutral	0,21	neutral	0,27	neutral	0,41	neutral	0,42	2	neutral	0,46	deleterious	0,75	neutral	-6	neutral	0,1	medium_impact	0,84	medium_impact	0,29	medium_impact	0,23	0,26	0,8	28,3	26,2	N	0,35	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9104	9104	T	C	MI.1232	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	578	193	F	S	tTc/tCc	-1,26	0	0	possibly_damaging	0,68	neutral	0,32	neutral	4,32	neutral	-2,89	deleterious	-3,8	neutral_impact	0,62	neutral	0,88	neutral	0,65	deleterious	2,66	20,5	0,27	0,65	neutral	0,45	neutral	0,31	neutral	0,42	neutral	0,45	1	neutral	0,74	neutral	0,32	neutral	-3	deleterious	0,52	low_impact	-1,07	medium_impact	0,11	medium_impact	-0,57	0,52	0,9	25,22	21,86	N	0,39	N	0,33	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4054	4054	C	A	MI.12320	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	748	250	L	I	Ctc/Atc	-6,44	0	0	benign	0	neutral	0,4	neutral	2,75	neutral	-0,91	neutral	-0,44	low_impact	0,82	neutral	0,86	neutral	0,95	deleterious	0,58	8	0,3	0,45	neutral	0,23	neutral	0,17	neutral	0,26	neutral	0,3	4	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,18	medium_impact	-0,47	0,48	0,8	28,3	26,2	N	0,47	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4054	4054	C	T	MI.12321	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	748	250	L	F	Ctc/Ttc	-6,44	0	0	benign	0	neutral	0,72	neutral	2,69	neutral	-1,4	neutral	-0,7	low_impact	0,86	neutral	0,85	neutral	0,92	neutral	-0,07	1,95	0,24	0,45	neutral	0,31	neutral	0,3	neutral	0,26	neutral	0,44	1	neutral	0,27	deleterious	0,86	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,51	medium_impact	-0,44	0,48	0,8	28,3	26,2	N	0,34	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4055	4055	T	G	MI.12322	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	749	250	L	R	cTc/cGc	-4,15	0	0	benign	0	neutral	0,34	neutral	2,7	deleterious	-3,87	neutral	-1,18	medium_impact	3	neutral	0,78	neutral	0,48	deleterious	0,77	9,28	0,04	0,35	neutral	0,29	disease	0,71	disease	0,53	disease	0,63	3	neutral	0,66	deleterious	0,67	neutral	-3	neutral	0,18	high_impact	2,07	medium_impact	0,11	medium_impact	1,43	0,2	0,8	28,3	26,2	N	0,33	N	0,03	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4055	4055	T	C	MI.12323	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	749	250	L	P	cTc/cCc	-4,15	0	0	benign	0,11	neutral	0,21	neutral	2,69	neutral	-2,82	neutral	-1,61	low_impact	0,96	neutral	0,81	neutral	0,69	deleterious	0,73	9,02	0,04	0,35	neutral	0,47	disease	0,67	neutral	0,33	disease	0,5	0	neutral	0,76	deleterious	0,55	neutral	-6	neutral	0,28	medium_impact	0,1	medium_impact	-0,05	medium_impact	-0,35	0,11	0,8	28,3	26,2	N	0,37	N	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4055	4055	T	A	MI.12324	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	749	250	L	H	cTc/cAc	-4,15	0	0	benign	0	neutral	0,54	neutral	2,67	deleterious	-3,97	neutral	-0,72	medium_impact	2,2	neutral	0,82	neutral	0,96	deleterious	0,46	7,1	0,07	0,35	neutral	0,28	neutral	0,41	neutral	0,32	neutral	0,44	1	neutral	0,46	deleterious	0,77	neutral	-3	neutral	0,14	high_impact	2,07	medium_impact	0,31	medium_impact	0,73	0,15	0,8	28,3	26,2	N	0,33	N	0,01	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4057	4057	T	A	MI.12325	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	751	251	S	T	Tcc/Acc	-9,43	0	0	benign	0,01	neutral	0,41	neutral	2,78	neutral	-0,81	neutral	0,16	neutral_impact	0,8	neutral	0,85	neutral	0,96	deleterious	0	2,57	0,34	0,5	neutral	0,16	neutral	0,12	neutral	0,27	neutral	0,3	4	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,08	medium_impact	1,12	medium_impact	0,19	medium_impact	-0,49	0,49	0,8	28,93	27,72	N	0,45	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4057	4057	T	C	MI.12326	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	751	251	S	P	Tcc/Ccc	-9,43	0	0	benign	0,41	neutral	0,21	neutral	2,74	neutral	-1,6	neutral	-1,1	neutral_impact	-0,04	neutral	0,72	neutral	0,64	deleterious	0,72	8,96	0,13	0,4	neutral	0,3	disease	0,59	neutral	0,28	neutral	0,45	1	neutral	0,76	neutral	0,4	neutral	-6	neutral	0,36	medium_impact	-0,6	medium_impact	-0,05	low_impact	-1,22	0,26	0,8	28,93	27,72	N	0,4	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4057	4057	T	G	MI.12327	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	751	251	S	A	Tcc/Gcc	-9,43	0	0	benign	0,01	neutral	0,53	neutral	2,8	neutral	-0,08	neutral	-0,26	low_impact	1,21	neutral	0,9	neutral	0,94	neutral	-0,07	1,96	0,39	0,5	neutral	0,14	neutral	0,16	neutral	0,39	neutral	0,3	4	neutral	0,46	deleterious	0,76	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,3	medium_impact	-0,13	0,28	0,8	28,93	27,72	N	0,38	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4058	4058	C	A	MI.12328	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	752	251	S	Y	tCc/tAc	-3,69	0	0	benign	0,17	neutral	1	neutral	2,72	neutral	-2,97	neutral	0,15	low_impact	0,94	neutral	0,9	neutral	0,9	neutral	-0,4	0,39	0,15	0,4	neutral	0,32	neutral	0,42	neutral	0,33	neutral	0,45	1	neutral	0,17	deleterious	0,92	neutral	-6	neutral	0,21	medium_impact	-0,1	high_impact	1,96	medium_impact	-0,37	0,13	0,8	28,93	27,72	N	0,28	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4058	4058	C	T	MI.12329	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	752	251	S	F	tCc/tTc	-3,69	0	0	benign	0,01	neutral	0,72	neutral	2,75	neutral	-1,94	neutral	0,37	neutral_impact	-0,31	neutral	0,85	neutral	0,98	neutral	-0,26	0,83	0,13	0,4	neutral	0,44	neutral	0,33	neutral	0,3	neutral	0,45	1	neutral	0,26	deleterious	0,86	neutral	-6	neutral	0,15	medium_impact	1,12	medium_impact	0,51	low_impact	-1,46	0,08	0,8	28,93	27,72	N	0,27	N	0,53	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9105	9105	C	G	MI.1233	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	579	193	F	L	ttC/ttG	0,36	0	0	benign	0,01	neutral	1	neutral	4,6	neutral	-0,5	deleterious	-2,5	neutral_impact	-0,32	neutral	0,95	neutral	0,85	neutral	1,09	11,17	0,44	0,65	disease	0,64	neutral	0,28	neutral	0,28	disease	0,57	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,17	medium_impact	1,14	high_impact	1,98	low_impact	-1,37	0,64	0,9	25,22	21,86	N	0,22	N	0,33	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4058	4058	C	G	MI.12330	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	752	251	S	C	tCc/tGc	-3,69	0	0	possibly_damaging	0,76	neutral	0,18	neutral	2,7	deleterious	-4,24	neutral	-0,93	low_impact	1,49	neutral	0,69	neutral	0,41	deleterious	0,82	9,6	0,15	0,45	disease	0,6	disease	0,54	neutral	0,34	neutral	0,48	0	neutral	0,87	neutral	0,21	neutral	-3	deleterious	0,53	low_impact	-1,22	medium_impact	-0,09	medium_impact	0,11	0,2	0,8	28,93	27,72	N	0,4	N	0,44	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4060	4060	C	A	MI.12331	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	754	252	P	T	Cct/Act	-6,9	0	0	benign	0,08	neutral	0,4	neutral	2,82	neutral	-1,81	deleterious	-5,38	low_impact	1,6	neutral	0,86	neutral	0,81	deleterious	2,77	21,2	0,22	0,45	neutral	0,2	disease	0,63	neutral	0,22	neutral	0,4	2	neutral	0,55	deleterious	0,66	neutral	-6	neutral	0,16	medium_impact	0,25	medium_impact	0,18	medium_impact	0,21	0,46	0,8	16,67	19,21	N	0,37	N	0,45	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4060	4060	C	T	MI.12332	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	754	252	P	S	Cct/Tct	-6,9	0	0	benign	0,2	neutral	0,42	neutral	2,82	neutral	-1,85	deleterious	-5,4	medium_impact	1,97	neutral	0,85	neutral	0,91	deleterious	3,95	23,6	0,24	0,45	neutral	0,17	disease	0,65	neutral	0,21	neutral	0,4	2	neutral	0,49	deleterious	0,61	neutral	-3	neutral	0,22	medium_impact	-0,19	medium_impact	0,2	medium_impact	0,53	0,08	0,8	16,67	19,21	N	0,37	N	0,44	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4060	4060	C	G	MI.12333	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	754	252	P	A	Cct/Gct	-6,9	0	0	possibly_damaging	0,52	neutral	0,5	neutral	2,87	neutral	-1,32	deleterious	-5,66	medium_impact	2,78	neutral	0,83	neutral	0,64	deleterious	3,19	22,7	0,22	0,45	neutral	0,14	disease	0,53	neutral	0,39	disease	0,52	0	neutral	0,51	deleterious	0,49	NA	0	neutral	0,36	medium_impact	-0,78	medium_impact	0,28	medium_impact	1,24	0,56	0,8	16,67	19,21	N	0,3	N	0,53	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4061	4061	C	A	MI.12334	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	755	252	P	H	cCt/cAt	0,91	0,01	0	probably_damaging	0,98	neutral	0,54	neutral	2,76	deleterious	-3,52	deleterious	-6,39	medium_impact	3,06	neutral	0,73	neutral	0,47	deleterious	4,07	23,7	0,13	0,4	neutral	0,33	disease	0,75	neutral	0,31	disease	0,57	1	neutral	0,97	neutral	0,28	deleterious	1	deleterious	0,72	low_impact	-2,34	medium_impact	0,31	medium_impact	1,48	0,18	0,8	16,67	19,21	N	0,31	N	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4061	4061	C	T	MI.12335	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	755	252	P	L	cCt/cTt	0,91	0,01	0	possibly_damaging	0,83	neutral	0,67	neutral	2,89	neutral	-1,4	deleterious	-7,17	medium_impact	1,97	neutral	0,71	neutral	0,54	deleterious	4,41	24,1	0,19	0,45	neutral	0,17	disease	0,8	neutral	0,24	neutral	0,48	0	neutral	0,8	neutral	0,42	NA	0	deleterious	0,51	low_impact	-1,4	medium_impact	0,45	medium_impact	0,53	0,4	0,8	16,67	19,21	N	0,3	N	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4061	4061	C	G	MI.12336	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	755	252	P	R	cCt/cGt	0,91	0,01	0	probably_damaging	0,94	neutral	0,34	neutral	2,79	neutral	-2,76	deleterious	-6,51	high_impact	3,75	neutral	0,69	neutral	0,47	deleterious	3,72	23,3	0,13	0,4	neutral	0,16	disease	0,83	disease	0,57	disease	0,71	4	neutral	0,95	neutral	0,2	deleterious	2	deleterious	0,67	low_impact	-1,87	medium_impact	0,11	high_impact	2,09	0,29	0,8	16,67	19,21	N	0,43	N	0,94	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4063	4063	G	C	MI.12337	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	757	253	E	Q	Gaa/Caa	-1,16	0	0	possibly_damaging	0,52	neutral	0,29	neutral	2,74	neutral	-0,94	neutral	-1,91	medium_impact	2,19	neutral	0,88	damaging	0,24	deleterious	2,38	18,67	0,27	0,45	neutral	0,27	disease	0,51	neutral	0,35	neutral	0,47	1	neutral	0,69	neutral	0,39	NA	0	deleterious	0,48	medium_impact	-0,78	medium_impact	0,06	medium_impact	0,72	0,61	0,8	18,24	25,06	N	0,38	N	0,88	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4063	4063	G	A	MI.12338	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	757	253	E	K	Gaa/Aaa	-1,16	0	0	possibly_damaging	0,9	neutral	0,29	neutral	2,77	neutral	-0,43	deleterious	-2,92	medium_impact	2,34	neutral	0,74	damaging	0,12	deleterious	4,58	24,4	0,13	0,4	neutral	0,23	disease	0,77	disease	0,53	disease	0,66	3	neutral	0,92	neutral	0,2	NA	0	deleterious	0,73	low_impact	-1,65	medium_impact	0,06	medium_impact	0,86	0,68	0,85	18,24	25,06	N	0,34	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4064	4064	A	C	MI.12339	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	758	253	E	A	gAa/gCa	5,27	1	0	possibly_damaging	0,9	neutral	0,5	neutral	2,81	neutral	0	deleterious	-4,38	low_impact	1,74	neutral	0,76	damaging	0,16	deleterious	3,8	23,4	0,16	0,45	neutral	0,14	disease	0,53	neutral	0,46	neutral	0,45	1	neutral	0,89	neutral	0,3	neutral	-3	deleterious	0,68	low_impact	-1,65	medium_impact	0,28	medium_impact	0,33	0,46	0,8	18,24	25,06	N	0,51	P	0,81	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9105	9105	C	A	MI.1234	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	579	193	F	L	ttC/ttA	0,36	0	0	benign	0,01	neutral	1	neutral	4,6	neutral	-0,5	deleterious	-2,5	neutral_impact	-0,32	neutral	0,95	neutral	0,85	neutral	1,4	12,8	0,44	0,65	disease	0,64	neutral	0,28	neutral	0,28	disease	0,57	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,17	medium_impact	1,14	high_impact	1,98	low_impact	-1,37	0,64	0,9	25,22	21,86	N	0,22	N	0,33	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4064	4064	A	T	MI.12340	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	758	253	E	V	gAa/gTa	5,27	1	0	probably_damaging	0,98	neutral	0,5	neutral	2,78	neutral	-0,32	deleterious	-5,17	medium_impact	2,27	neutral	0,73	damaging	0,14	deleterious	4,36	24,1	0,09	0,4	neutral	0,16	disease	0,77	neutral	0,47	disease	0,6	2	neutral	0,98	neutral	0,26	deleterious	1	deleterious	0,73	low_impact	-2,34	medium_impact	0,28	medium_impact	0,79	0,37	0,8	18,24	25,06	N	0,46	N	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4064	4064	A	G	MI.12341	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	758	253	E	G	gAa/gGa	5,27	1	0	probably_damaging	0,97	neutral	0,34	neutral	2,71	neutral	-1,7	deleterious	-5,05	low_impact	1,19	neutral	0,9	neutral	0,35	deleterious	4,37	24,1	0,13	0,4	neutral	0,26	disease	0,69	disease	0,54	disease	0,53	1	neutral	0,97	neutral	0,19	neutral	-2	deleterious	0,73	low_impact	-2,17	medium_impact	0,11	medium_impact	-0,15	0,3	0,8	18,24	25,06	N	0,57	P	0,83	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4065	4065	A	C	MI.12342	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	759	253	E	D	gaA/gaC	5,04	1	0	probably_damaging	0,92	neutral	0,21	neutral	2,72	neutral	-1,33	neutral	-1,91	low_impact	1,78	neutral	0,81	damaging	0,19	deleterious	3,7	23,3	0,33	0,5	neutral	0,34	neutral	0,46	neutral	0,44	neutral	0,46	1	neutral	0,95	neutral	0,15	neutral	-2	deleterious	0,69	low_impact	-1,75	medium_impact	-0,05	medium_impact	0,37	0,51	0,8	18,24	25,06	P	0,59	P	0,88	polymorphism	1	0,03	rs386828932	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4065	4065	A	T	MI.12343	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	759	253	E	D	gaA/gaT	5,04	1	0	probably_damaging	0,92	neutral	0,21	neutral	2,72	neutral	-1,33	neutral	-1,91	low_impact	1,78	neutral	0,81	damaging	0,19	deleterious	3,81	23,4	0,33	0,5	neutral	0,34	neutral	0,46	neutral	0,44	neutral	0,46	1	neutral	0,95	neutral	0,15	neutral	-2	deleterious	0,69	low_impact	-1,75	medium_impact	-0,05	medium_impact	0,37	0,51	0,8	18,24	25,06	P	0,6	P	0,88	polymorphism	1	0,03	rs386828932	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4066	4066	C	T	MI.12344	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	760	254	L	F	Ctc/Ttc	0,91	0,33	0	benign	0,02	neutral	0,84	neutral	2,66	neutral	-2,37	neutral	-2,27	low_impact	1,7	neutral	0,89	neutral	0,85	deleterious	2,89	21,8	0,18	0,45	neutral	0,3	neutral	0,34	neutral	0,26	neutral	0,45	1	neutral	0,12	deleterious	0,91	neutral	-6	neutral	0,15	medium_impact	0,84	medium_impact	0,68	medium_impact	0,3	0,48	0,8	26,1	19,12	N	0,29	N	0,63	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4066	4066	C	G	MI.12345	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	760	254	L	V	Ctc/Gtc	0,91	0,33	0	benign	0,18	neutral	0,54	neutral	2,73	neutral	-1,35	neutral	-1,6	medium_impact	2,12	neutral	0,88	neutral	0,69	deleterious	3,4	23	0,29	0,45	neutral	0,16	neutral	0,31	neutral	0,45	neutral	0,45	1	neutral	0,35	deleterious	0,68	neutral	-3	neutral	0,2	medium_impact	-0,13	medium_impact	0,31	medium_impact	0,66	0,37	0,8	26,1	19,12	N	0,3	N	0,32	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4066	4066	C	A	MI.12346	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	760	254	L	I	Ctc/Atc	0,91	0,33	0	benign	0,26	neutral	0,5	neutral	2,78	neutral	-1,26	neutral	-1,01	low_impact	1,26	neutral	0,87	neutral	0,94	deleterious	3,02	22,3	0,31	0,45	neutral	0,26	neutral	0,14	neutral	0,27	neutral	0,27	5	neutral	0,4	deleterious	0,62	neutral	-6	neutral	0,24	medium_impact	-0,32	medium_impact	0,28	medium_impact	-0,09	0,61	0,8	26,1	19,12	N	0,37	N	0,09	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4067	4067	T	A	MI.12347	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	761	254	L	H	cTc/cAc	-2,77	0	0	benign	0,02	neutral	0,52	neutral	2,64	deleterious	-4,75	deleterious	-4,48	high_impact	3,74	neutral	0,77	neutral	0,48	deleterious	4,4	24,1	0,06	0,35	disease	0,59	disease	0,6	disease	0,59	disease	0,68	4	neutral	0,45	deleterious	0,75	neutral	-2	neutral	0,26	medium_impact	0,84	medium_impact	0,29	high_impact	2,08	0,17	0,8	26,1	19,12	N	0,34	N	0,86	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4067	4067	T	G	MI.12348	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	761	254	L	R	cTc/cGc	-2,77	0	0	possibly_damaging	0,47	neutral	0,33	neutral	2,67	deleterious	-4,12	deleterious	-4,08	medium_impact	3,4	neutral	0,65	neutral	0,37	deleterious	4,29	24	0,03	0,35	neutral	0,5	disease	0,75	disease	0,72	disease	0,73	5	neutral	0,63	neutral	0,43	NA	0	deleterious	0,59	medium_impact	-0,7	medium_impact	0,1	medium_impact	1,78	0,2	0,8	26,1	19,12	N	0,35	N	0,96	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4067	4067	T	C	MI.12349	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	761	254	L	P	cTc/cCc	-2,77	0	0	possibly_damaging	0,55	neutral	0,27	neutral	2,68	deleterious	-3,46	deleterious	-4,78	medium_impact	2,59	damaging	0,59	neutral	0,35	deleterious	4,04	23,7	0,04	0,35	neutral	0,33	disease	0,69	disease	0,64	disease	0,55	1	neutral	0,72	neutral	0,36	NA	0	deleterious	0,63	medium_impact	-0,83	medium_impact	0,03	medium_impact	1,07	0,14	0,8	26,1	19,12	N	0,31	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9106	9106	A	T	MI.1235	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	580	194	T	S	Aca/Tca	-2,42	0	0	probably_damaging	0,99	neutral	0,18	neutral	4,32	neutral	-1,28	neutral	-1,77	neutral_impact	0	neutral	0,87	neutral	0,89	deleterious	2,12	16,97	0,39	0,65	neutral	0,35	neutral	0,23	neutral	0,33	neutral	0,42	2	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,68	low_impact	-2,65	medium_impact	-0,08	low_impact	-1,1	0,62	0,9	15,93	19,05	N	0,43	N	0,06	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4069	4069	T	G	MI.12350	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	763	255	Y	D	Tac/Gac	-9,66	0	0	possibly_damaging	0,81	neutral	0,2	neutral	2,81	neutral	-1,05	deleterious	-2,54	low_impact	1,34	neutral	0,87	neutral	0,63	deleterious	2,26	17,88	0,08	0,35	neutral	0,26	disease	0,72	disease	0,58	disease	0,71	4	neutral	0,89	neutral	0,2	neutral	-3	deleterious	0,61	low_impact	-1,34	medium_impact	-0,06	medium_impact	-0,02	0,3	0,8	27,99	30,66	N	0,36	N	0,92	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4069	4069	T	A	MI.12351	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	763	255	Y	N	Tac/Aac	-9,66	0	0	possibly_damaging	0,68	neutral	0,32	neutral	2,84	neutral	-0,86	neutral	-1,88	low_impact	0,82	neutral	0,91	neutral	0,87	deleterious	0,8	9,45	0,11	0,4	neutral	0,24	disease	0,64	neutral	0,36	neutral	0,47	1	neutral	0,75	neutral	0,32	neutral	-3	deleterious	0,52	low_impact	-1,06	medium_impact	0,09	medium_impact	-0,47	0,28	0,8	27,99	30,66	N	0,41	N	0,8	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4069	4069	T	C	MI.12352	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	763	255	Y	H	Tac/Cac	-9,66	0	0	benign	0,05	neutral	0,51	neutral	2,78	neutral	-1,59	neutral	-1,75	low_impact	1,07	neutral	0,89	neutral	0,91	neutral	-0,25	0,87	0,16	0,45	neutral	0,34	neutral	0,45	neutral	0,4	neutral	0,49	0	neutral	0,44	deleterious	0,73	neutral	-6	neutral	0,18	medium_impact	0,45	medium_impact	0,29	medium_impact	-0,25	0,33	0,8	27,99	30,66	N	0,37	N	0,74	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4070	4070	A	G	MI.12353	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	764	255	Y	C	tAc/tGc	1,6	0	0	probably_damaging	0,94	neutral	0,17	neutral	2,76	neutral	-2,46	neutral	-2,19	medium_impact	2,31	neutral	0,95	neutral	0,81	deleterious	2,21	17,55	0,07	0,35	neutral	0,37	disease	0,74	neutral	0,39	disease	0,54	1	neutral	0,97	neutral	0,12	deleterious	1	deleterious	0,68	low_impact	-1,87	medium_impact	-0,11	medium_impact	0,83	0,09	0,8	27,99	30,66	N	0,45	N	0,49	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4070	4070	A	C	MI.12354	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	764	255	Y	S	tAc/tCc	1,6	0	0	possibly_damaging	0,65	neutral	0,41	neutral	2,84	neutral	-0,19	neutral	-1,08	neutral_impact	0,12	neutral	0,8	neutral	0,96	deleterious	0,41	6,66	0,08	0,35	neutral	0,12	neutral	0,4	neutral	0,38	neutral	0,43	1	neutral	0,67	neutral	0,38	neutral	-3	neutral	0,43	low_impact	-1	medium_impact	0,19	low_impact	-1,08	0,36	0,8	27,99	30,66	N	0,35	N	0,8	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4070	4070	A	T	MI.12355	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	764	255	Y	F	tAc/tTc	1,6	0	0	benign	0,01	neutral	0,71	neutral	2,8	neutral	0,23	neutral	0,61	neutral_impact	-0,77	neutral	0,78	neutral	0,96	neutral	-0,41	0,37	0,21	0,45	neutral	0,2	neutral	0,16	neutral	0,25	neutral	0,24	5	neutral	0,26	deleterious	0,85	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	0,49	low_impact	-1,86	0,46	0,8	27,99	30,66	N	0,3	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4072	4072	A	C	MI.12356	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	766	256	T	P	Aca/Cca	-5,07	0	0	probably_damaging	0,96	neutral	0,21	neutral	2,72	neutral	-1,86	deleterious	-3,24	low_impact	1,52	neutral	0,76	neutral	0,32	deleterious	2,42	18,94	0,06	0,35	neutral	0,46	disease	0,74	neutral	0,5	disease	0,54	1	neutral	0,97	neutral	0,13	neutral	-2	deleterious	0,77	low_impact	-2,05	medium_impact	-0,05	medium_impact	0,14	0,43	0,8	54,72	10,65	N	0,29	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4072	4072	A	T	MI.12357	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	766	256	T	S	Aca/Tca	-5,07	0	0	benign	0,13	neutral	0,43	neutral	2,82	neutral	-1,1	neutral	-1,74	low_impact	1,32	neutral	0,86	neutral	0,89	deleterious	1,83	15,15	0,36	0,5	neutral	0,19	neutral	0,21	neutral	0,28	neutral	0,37	3	neutral	0,5	deleterious	0,65	neutral	-6	neutral	0,19	medium_impact	0,02	medium_impact	0,21	medium_impact	-0,04	0,72	0,85	54,72	10,65	N	0,42	N	0,08	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4072	4072	A	G	MI.12358	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	766	256	T	A	Aca/Gca	-5,07	0	0	possibly_damaging	0,64	neutral	0,52	neutral	2,8	neutral	-0,05	deleterious	-2,75	medium_impact	2,57	neutral	0,82	neutral	0,56	deleterious	2,35	18,48	0,26	0,45	neutral	0,18	neutral	0,37	neutral	0,42	neutral	0,44	1	neutral	0,61	neutral	0,44	NA	0	deleterious	0,48	medium_impact	-0,99	medium_impact	0,29	medium_impact	1,06	0,45	0,8	54,72	10,65	N	0,3	N	0,65	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4073	4073	C	T	MI.12359	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	767	256	T	M	aCa/aTa	-0,7	0	0	probably_damaging	0,98	neutral	0,23	neutral	2,74	neutral	-1,66	deleterious	-3,98	medium_impact	3,26	neutral	0,67	damaging	0,13	deleterious	4,12	23,8	0,1	0,4	neutral	0,29	disease	0,68	neutral	0,37	disease	0,5	0	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,68	low_impact	-2,34	medium_impact	-0,02	medium_impact	1,66	0,73	0,85	54,72	10,65	N	0,36	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9106	9106	A	G	MI.1236	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	580	194	T	A	Aca/Gca	-2,42	0	0	probably_damaging	0,99	neutral	0,48	neutral	4,38	neutral	-0,11	neutral	-1,56	neutral_impact	-0,38	neutral	0,94	neutral	0,84	deleterious	2,03	16,43	0,42	0,65	neutral	0,28	neutral	0,18	neutral	0,35	neutral	0,3	4	deleterious	0,99	neutral	0,25	neutral	-2	deleterious	0,67	low_impact	-2,65	medium_impact	0,27	low_impact	-1,42	0,45	0,9	15,93	19,05	N	0,33	N	0,23	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4073	4073	C	A	MI.12360	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	767	256	T	K	aCa/aAa	-0,7	0	0	possibly_damaging	0,83	neutral	0,31	neutral	2,75	neutral	-2,18	deleterious	-3,75	medium_impact	2,81	neutral	0,66	damaging	0,14	deleterious	4,55	24,4	0,06	0,35	neutral	0,32	disease	0,78	neutral	0,41	disease	0,67	3	neutral	0,86	neutral	0,24	NA	0	deleterious	0,72	low_impact	-1,4	medium_impact	0,08	medium_impact	1,27	0,54	0,8	54,72	10,65	N	0,33	N	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4075	4075	A	G	MI.12361	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	769	257	T	A	Aca/Gca	-6,44	0	0	benign	0,01	neutral	0,5	neutral	2,8	neutral	0,22	neutral	-0,63	neutral_impact	0,52	neutral	0,86	neutral	0,97	deleterious	2,19	17,48	0,23	0,45	neutral	0,18	neutral	0,19	neutral	0,36	neutral	0,37	3	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	0,28	medium_impact	-0,73	0,48	0,8	25,79	18,66	N	0,35	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4075	4075	A	T	MI.12362	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	769	257	T	S	Aca/Tca	-6,44	0	0	benign	0,18	neutral	0,53	neutral	2,76	neutral	-0,71	neutral	-1,12	low_impact	1,31	neutral	0,75	neutral	0,68	deleterious	2,38	18,69	0,36	0,5	neutral	0,19	neutral	0,32	neutral	0,25	neutral	0,45	1	neutral	0,36	deleterious	0,68	neutral	-6	neutral	0,19	medium_impact	-0,13	medium_impact	0,3	medium_impact	-0,04	0,68	0,85	25,79	18,66	N	0,39	N	0,2	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4075	4075	A	C	MI.12363	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	769	257	T	P	Aca/Cca	-6,44	0	0	possibly_damaging	0,55	neutral	0,33	neutral	2,71	neutral	-1,5	neutral	-2,25	neutral_impact	0,76	neutral	0,67	neutral	0,56	deleterious	3,54	23,1	0,05	0,35	neutral	0,45	disease	0,74	disease	0,53	disease	0,64	3	neutral	0,66	neutral	0,39	neutral	-3	deleterious	0,61	medium_impact	-0,83	medium_impact	0,1	medium_impact	-0,53	0,46	0,8	25,79	18,66	N	0,31	N	0,94	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4076	4076	C	T	MI.12364	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	770	257	T	M	aCa/aTa	-2,08	0	0	benign	0,03	neutral	0,27	neutral	2,76	neutral	-1,19	neutral	1,18	neutral_impact	0,25	neutral	0,86	neutral	0,95	deleterious	2,15	17,15	0,11	0,4	neutral	0,25	neutral	0,22	neutral	0,25	neutral	0,41	2	neutral	0,71	deleterious	0,62	neutral	-6	neutral	0,11	medium_impact	0,67	medium_impact	0,03	medium_impact	-0,97	0,63	0,8	25,79	18,66	N	0,42	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4076	4076	C	A	MI.12365	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	770	257	T	K	aCa/aAa	-2,08	0	0	benign	0,26	neutral	0,29	neutral	2,74	neutral	-1,87	neutral	-1,91	medium_impact	2,17	neutral	0,69	neutral	0,46	deleterious	4,63	24,5	0,06	0,35	neutral	0,34	disease	0,58	disease	0,61	disease	0,7	4	neutral	0,65	deleterious	0,52	neutral	-3	neutral	0,36	medium_impact	-0,32	medium_impact	0,06	medium_impact	0,71	0,55	0,8	25,79	18,66	N	0,39	N	0,9	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4078	4078	T	C	MI.12366	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	772	258	Y	H	Tat/Cat	-12,65	0	0	benign	0,29	neutral	0,54	neutral	2,77	neutral	-1,48	neutral	1,38	low_impact	1,2	neutral	0,74	neutral	0,51	deleterious	2,06	16,57	0,19	0,45	neutral	0,35	neutral	0,38	neutral	0,36	neutral	0,45	1	neutral	0,36	deleterious	0,63	neutral	-6	neutral	0,22	medium_impact	-0,39	medium_impact	0,31	medium_impact	-0,14	0,38	0,8	28,62	36,47	N	0,3	N	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4078	4078	T	G	MI.12367	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	772	258	Y	D	Tat/Gat	-12,65	0	0	benign	0,07	neutral	0,2	neutral	2,77	neutral	-1,82	neutral	1,65	low_impact	0,85	neutral	0,85	neutral	0,68	deleterious	2,35	18,52	0,06	0,35	neutral	0,4	disease	0,66	neutral	0,44	disease	0,51	0	neutral	0,78	deleterious	0,57	neutral	-6	neutral	0,21	medium_impact	0,3	medium_impact	-0,06	medium_impact	-0,45	0,32	0,8	28,62	36,47	N	0,3	N	0,26	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4078	4078	T	A	MI.12368	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	772	258	Y	N	Tat/Aat	-12,65	0	0	benign	0	neutral	0,31	neutral	2,8	neutral	-1,03	neutral	4,28	neutral_impact	-2,11	neutral	0,67	neutral	0,96	neutral	-0,31	0,63	0,1	0,4	neutral	0,15	neutral	0,15	neutral	0,25	neutral	0,29	4	neutral	0,69	deleterious	0,66	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,08	low_impact	-3,03	0,46	0,8	28,62	36,47	N	0,41	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4079	4079	A	C	MI.12369	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	773	258	Y	S	tAt/tCt	-0,47	0	0	benign	0	neutral	0,4	neutral	2,84	neutral	-0,25	neutral	2,72	neutral_impact	-1,43	neutral	0,79	neutral	0,96	deleterious	0,17	4,39	0,08	0,35	neutral	0,14	neutral	0,28	neutral	0,24	neutral	0,41	2	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,18	low_impact	-2,44	0,35	0,8	28,62	36,47	N	0,28	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9106	9106	A	C	MI.1237	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	580	194	T	P	Aca/Cca	-2,42	0	0	probably_damaging	1	neutral	0,14	neutral	4,3	neutral	-1,86	deleterious	-3,23	neutral_impact	0,68	neutral	0,73	neutral	0,38	deleterious	2,5	19,48	0,15	0,65	disease	0,59	disease	0,75	disease	0,6	disease	0,61	2	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,8	low_impact	-3,6	medium_impact	-0,15	medium_impact	-0,52	0,58	0,9	15,93	19,05	N	0,26	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4079	4079	A	G	MI.12370	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	773	258	Y	C	tAt/tGt	-0,47	0	0	benign	0	neutral	0,18	neutral	2,77	neutral	-1,91	neutral	-0,4	neutral_impact	0,5	neutral	0,78	neutral	0,76	deleterious	0,43	6,84	0,05	0,35	neutral	0,35	disease	0,63	neutral	0,26	neutral	0,5	0	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,15	high_impact	2,07	medium_impact	-0,09	medium_impact	-0,75	0,21	0,8	28,62	36,47	N	0,39	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4079	4079	A	T	MI.12371	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	773	258	Y	F	tAt/tTt	-0,47	0	0	benign	0,11	neutral	0,71	neutral	2,84	neutral	1,01	neutral	-0,53	neutral_impact	-0,46	neutral	0,87	neutral	0,84	neutral	1,31	12,33	0,35	0,5	neutral	0,14	neutral	0,3	neutral	0,18	neutral	0,43	1	neutral	0,18	deleterious	0,8	neutral	-6	neutral	0,14	medium_impact	0,1	medium_impact	0,49	low_impact	-1,59	0,57	0,8	28,62	36,47	N	0,37	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4081	4081	T	C	MI.12372	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	775	259	F	L	Ttt/Ctt	-5,07	0	0	benign	0,08	neutral	0,95	neutral	2,87	neutral	-1,08	neutral	1,53	neutral_impact	-0,14	neutral	0,81	neutral	0,91	neutral	1,58	13,77	0,17	0,45	neutral	0,17	neutral	0,17	neutral	0,27	neutral	0,24	5	neutral	0,02	deleterious	0,94	neutral	-6	neutral	0,12	medium_impact	0,25	medium_impact	0,99	low_impact	-1,31	0,68	0,85	57,55	10,31	N	0,25	N	0,92	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	T4081C	LHON (putative)	+	-	Reported	1
chrM	4081	4081	T	A	MI.12373	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	775	259	F	I	Ttt/Att	-5,07	0	0	possibly_damaging	0,63	neutral	0,51	neutral	2,82	neutral	-1,97	neutral	0,44	low_impact	1,52	neutral	0,74	neutral	0,42	deleterious	3,5	23,1	0,12	0,4	neutral	0,22	neutral	0,41	neutral	0,38	neutral	0,44	1	neutral	0,61	neutral	0,44	neutral	-3	deleterious	0,49	medium_impact	-0,97	medium_impact	0,29	medium_impact	0,14	0,51	0,8	57,55	10,31	N	0,38	N	0,97	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4081	4081	T	G	MI.12374	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	775	259	F	V	Ttt/Gtt	-5,07	0	0	possibly_damaging	0,74	neutral	0,55	neutral	2,84	neutral	-1,82	neutral	-0,43	medium_impact	2,21	neutral	0,72	damaging	0,19	deleterious	4,22	23,9	0,09	0,35	neutral	0,21	disease	0,65	neutral	0,43	neutral	0,5	0	neutral	0,71	neutral	0,41	NA	0	deleterious	0,53	low_impact	-1,18	medium_impact	0,32	medium_impact	0,74	0,35	0,8	57,55	10,31	N	0,27	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4082	4082	T	C	MI.12375	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	776	259	F	S	tTt/tCt	-0,01	0	0	probably_damaging	0,96	neutral	0,44	neutral	2,77	deleterious	-3,43	deleterious	-2,88	medium_impact	2,44	neutral	0,78	damaging	0,15	deleterious	4,31	24	0,05	0,35	neutral	0,46	disease	0,7	disease	0,59	disease	0,7	4	neutral	0,95	neutral	0,24	deleterious	1	deleterious	0,74	low_impact	-2,05	medium_impact	0,22	medium_impact	0,94	0,39	0,8	57,55	10,31	N	0,23	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4082	4082	T	A	MI.12376	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	776	259	F	Y	tTt/tAt	-0,01	0	0	possibly_damaging	0,89	neutral	0,96	neutral	2,71	deleterious	-3,06	neutral	-1,27	medium_impact	2,87	neutral	0,73	damaging	0,16	deleterious	4,22	23,9	0,16	0,45	disease	0,54	disease	0,53	disease	0,51	disease	0,54	1	neutral	0,88	deleterious	0,54	NA	0	deleterious	0,69	low_impact	-1,6	medium_impact	1,05	medium_impact	1,32	0,62	0,8	57,55	10,31	N	0,3	N	0,88	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4082	4082	T	G	MI.12377	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	776	259	F	C	tTt/tGt	-0,01	0	0	probably_damaging	0,98	neutral	0,2	neutral	2,69	deleterious	-4,84	neutral	-2,23	high_impact	3,76	neutral	0,68	damaging	0,13	deleterious	4,19	23,8	0,05	0,35	disease	0,65	disease	0,77	disease	0,61	disease	0,73	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,76	low_impact	-2,34	medium_impact	-0,06	high_impact	2,1	0,25	0,8	57,55	10,31	N	0,37	N	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4083	4083	T	A	MI.12378	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	777	259	F	L	ttT/ttA	7,34	0,98	0	benign	0,08	neutral	0,95	neutral	2,87	neutral	-1,08	neutral	1,53	neutral_impact	-0,14	neutral	0,81	neutral	0,91	deleterious	1,82	15,12	0,17	0,45	neutral	0,17	neutral	0,17	neutral	0,27	neutral	0,24	5	neutral	0,02	deleterious	0,94	neutral	-6	neutral	0,12	medium_impact	0,25	medium_impact	0,99	low_impact	-1,31	0,68	0,85	57,55	10,31	P	0,57	P	0,92	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4083	4083	T	G	MI.12379	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	777	259	F	L	ttT/ttG	7,34	0,98	0	benign	0,08	neutral	0,95	neutral	2,87	neutral	-1,08	neutral	1,53	neutral_impact	-0,14	neutral	0,81	neutral	0,91	neutral	1,72	14,51	0,17	0,45	neutral	0,17	neutral	0,17	neutral	0,27	neutral	0,24	5	neutral	0,02	deleterious	0,94	neutral	-6	neutral	0,12	medium_impact	0,25	medium_impact	0,99	low_impact	-1,31	0,68	0,85	57,55	10,31	P	0,57	P	0,92	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9107	9107	C	A	MI.1238	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	581	194	T	K	aCa/aAa	-0,8	0	0	probably_damaging	1	neutral	0,06	neutral	4,29	neutral	-2,11	deleterious	-3,1	medium_impact	2,1	neutral	0,83	neutral	0,44	deleterious	4,55	24,3	0,12	0,65	neutral	0,42	disease	0,67	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	-0,38	medium_impact	0,7	0,7	0,9	15,93	19,05	N	0,33	N	0,83	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4084	4084	G	C	MI.12380	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	778	260	V	L	Gtc/Ctc	-8,51	0	0	benign	0,03	neutral	1	neutral	2,81	neutral	0,72	neutral	0,37	neutral_impact	-0,57	neutral	0,75	neutral	0,7	neutral	1,71	14,47	0,19	0,45	neutral	0,13	neutral	0,41	neutral	0,4	neutral	0,43	1	neutral	0,03	deleterious	0,99	neutral	-6	neutral	0,1	medium_impact	0,67	high_impact	1,96	low_impact	-1,69	0,45	0,8	24,53	19,91	N	0,26	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4084	4084	G	T	MI.12381	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	778	260	V	F	Gtc/Ttc	-8,51	0	0	benign	0,38	neutral	0,89	neutral	2,69	neutral	-0,71	neutral	-1,29	neutral_impact	-0,46	neutral	0,71	neutral	0,63	deleterious	2,32	18,3	0,07	0,35	neutral	0,27	disease	0,54	neutral	0,32	neutral	0,44	1	neutral	0,28	deleterious	0,76	neutral	-6	neutral	0,24	medium_impact	-0,55	medium_impact	0,78	low_impact	-1,59	0,44	0,8	24,53	19,91	N	0,24	N	0,2	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4084	4084	G	A	MI.12382	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	778	260	V	I	Gtc/Atc	-8,51	0	0	benign	0,01	neutral	0,55	neutral	2,77	neutral	0,2	neutral	-0,01	neutral_impact	-0,66	neutral	0,8	neutral	0,96	deleterious	0,61	8,19	0,3	0,45	neutral	0,14	neutral	0,1	neutral	0,29	neutral	0,3	4	neutral	0,43	deleterious	0,77	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,32	low_impact	-1,76	0,68	0,85	24,53	19,91	N	0,31	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4085	4085	T	C	MI.12383	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	779	260	V	A	gTc/gCc	1,37	0	0	benign	0,01	neutral	0,5	neutral	2,76	neutral	-0,8	neutral	-1,66	neutral_impact	-0,94	neutral	0,82	neutral	0,96	deleterious	0,55	7,81	0,09	0,4	neutral	0,18	neutral	0,17	neutral	0,34	neutral	0,29	4	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	0,28	low_impact	-2,01	0,17	0,8	24,53	19,91	N	0,36	N	0,03	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4085	4085	T	G	MI.12384	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	779	260	V	G	gTc/gGc	1,37	0	0	benign	0,18	neutral	0,34	neutral	2,65	neutral	-1,98	deleterious	-3,67	neutral_impact	-0,16	neutral	0,71	neutral	0,56	deleterious	1,98	16,1	0,05	0,35	neutral	0,39	neutral	0,47	neutral	0,37	neutral	0,45	1	neutral	0,59	deleterious	0,58	neutral	-6	neutral	0,2	medium_impact	-0,13	medium_impact	0,11	low_impact	-1,33	0,3	0,8	24,53	19,91	N	0,35	N	0,34	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4085	4085	T	A	MI.12385	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	779	260	V	D	gTc/gAc	1,37	0	0	possibly_damaging	0,47	neutral	0,2	neutral	2,63	deleterious	-4,37	deleterious	-3,63	low_impact	1,26	neutral	0,7	neutral	0,5	deleterious	2,64	20,5	0,02	0,35	neutral	0,35	disease	0,71	disease	0,67	disease	0,74	5	neutral	0,77	neutral	0,37	neutral	-3	neutral	0,33	medium_impact	-0,7	medium_impact	-0,06	medium_impact	-0,09	0,27	0,8	24,53	19,91	N	0,33	N	0,38	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4087	4087	A	C	MI.12386	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	781	261	T	P	Acc/Ccc	-3,46	0	0	possibly_damaging	0,55	neutral	0,2	neutral	2,71	neutral	-2,31	deleterious	-2,87	medium_impact	2,8	neutral	0,82	neutral	0,58	deleterious	0,64	8,44	0,05	0,35	disease	0,52	disease	0,81	disease	0,54	disease	0,74	5	neutral	0,79	neutral	0,33	NA	0	deleterious	0,58	medium_impact	-0,83	medium_impact	-0,06	medium_impact	1,26	0,37	0,8	17,3	13,67	N	0,34	N	0,79	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4087	4087	A	G	MI.12387	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	781	261	T	A	Acc/Gcc	-3,46	0	0	benign	0,01	neutral	0,51	neutral	2,8	neutral	0,75	neutral	-1,29	low_impact	0,92	neutral	0,91	neutral	0,94	deleterious	0,07	3,28	0,23	0,45	neutral	0,18	neutral	0,28	neutral	0,38	neutral	0,43	1	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	0,29	medium_impact	-0,39	0,4	0,8	17,3	13,67	N	0,32	N	0,17	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4087	4087	A	T	MI.12388	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	781	261	T	S	Acc/Tcc	-3,46	0	0	benign	0,02	neutral	0,41	neutral	2,75	neutral	-0,75	neutral	-1,27	medium_impact	2,11	neutral	0,83	neutral	0,77	deleterious	-0,02	2,42	0,35	0,5	neutral	0,28	neutral	0,41	neutral	0,36	neutral	0,45	1	neutral	0,57	deleterious	0,7	neutral	-3	neutral	0,13	medium_impact	0,84	medium_impact	0,19	medium_impact	0,65	0,49	0,8	17,3	13,67	N	0,39	N	0,21	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4088	4088	C	G	MI.12389	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	782	261	T	S	aCc/aGc	-2,54	0	0	benign	0,02	neutral	0,41	neutral	2,75	neutral	-0,75	neutral	-1,27	medium_impact	2,11	neutral	0,83	neutral	0,77	deleterious	0,18	4,45	0,35	0,5	neutral	0,28	neutral	0,41	neutral	0,36	neutral	0,45	1	neutral	0,57	deleterious	0,7	neutral	-3	neutral	0,13	medium_impact	0,84	medium_impact	0,19	medium_impact	0,65	0,49	0,8	17,3	13,67	N	0,39	N	0,21	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9107	9107	C	T	MI.1239	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	581	194	T	M	aCa/aTa	-0,8	0	0	probably_damaging	1	neutral	0,36	neutral	4,33	neutral	-0,92	neutral	-1,36	neutral_impact	0,02	neutral	0,93	neutral	0,89	deleterious	2,88	21,7	0,29	0,65	neutral	0,43	neutral	0,29	neutral	0,33	neutral	0,44	1	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	0,15	low_impact	-1,08	0,73	0,9	15,93	19,05	N	0,37	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4088	4088	C	T	MI.12390	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	782	261	T	I	aCc/aTc	-2,54	0	0	benign	0,01	neutral	0,4	neutral	2,91	neutral	0,86	neutral	-0,22	neutral_impact	0,15	neutral	0,82	neutral	0,92	neutral	-0,15	1,4	0,12	0,4	neutral	0,13	neutral	0,22	neutral	0,26	neutral	0,34	3	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	0,18	low_impact	-1,06	0,59	0,8	17,3	13,67	N	0,35	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4088	4088	C	A	MI.12391	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	782	261	T	N	aCc/aAc	-2,54	0	0	benign	0,38	neutral	0,31	neutral	2,72	neutral	-2,27	neutral	-2,43	medium_impact	2,46	neutral	0,69	neutral	0,54	deleterious	0,74	9,1	0,23	0,45	neutral	0,46	disease	0,66	neutral	0,4	neutral	0,49	0	neutral	0,63	neutral	0,47	neutral	-3	neutral	0,28	medium_impact	-0,55	medium_impact	0,08	medium_impact	0,96	0,64	0,8	17,3	13,67	N	0,39	N	0,57	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4090	4090	A	G	MI.12392	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	784	262	K	E	Aag/Gag	-8,97	0	0	probably_damaging	1	neutral	0,25	neutral	2,4	deleterious	-3,05	deleterious	-3,68	high_impact	3,55	neutral	0,8	neutral	0,66	deleterious	4,09	23,7	0,09	0,35	neutral	0,41	disease	0,85	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,01	medium_impact	1,91	0,29	0,8	21,7	15,68	N	0,4	N	0,3	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4090	4090	A	C	MI.12393	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	784	262	K	Q	Aag/Cag	-8,97	0	0	probably_damaging	1	neutral	0,24	neutral	2,38	deleterious	-3,21	deleterious	-3,68	high_impact	4,04	neutral	0,76	damaging	0,13	deleterious	3,57	23,1	0,22	0,45	neutral	0,49	disease	0,81	disease	0,68	disease	0,64	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	-0,01	high_impact	2,34	0,36	0,8	21,7	15,68	N	0,33	N	0,62	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4091	4091	A	C	MI.12394	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	785	262	K	T	aAg/aCg	5,5	1	0	probably_damaging	1	neutral	0,5	neutral	2,37	deleterious	-3,71	deleterious	-5,5	high_impact	3,9	neutral	0,71	damaging	0,11	deleterious	3,82	23,4	0,08	0,35	disease	0,54	disease	0,78	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,28	high_impact	2,22	0,26	0,8	21,7	15,68	P	0,59	P	0,87	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4091	4091	A	T	MI.12395	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	785	262	K	M	aAg/aTg	5,5	1	0	probably_damaging	1	neutral	0,34	neutral	2,35	deleterious	-4,77	deleterious	-5,48	medium_impact	3,12	neutral	0,77	damaging	0,12	deleterious	4,13	23,8	0,08	0,35	disease	0,61	disease	0,82	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,77	low_impact	-3,57	medium_impact	0,11	medium_impact	1,54	0,18	0,8	21,7	15,68	N	0,54	P	0,87	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4092	4092	G	T	MI.12396	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	786	262	K	N	aaG/aaT	6,65	1	0,01	probably_damaging	1	neutral	0,28	neutral	2,36	deleterious	-3,88	deleterious	-4,59	high_impact	3,55	neutral	0,75	damaging	0,12	deleterious	4,17	23,8	0,23	0,45	disease	0,55	disease	0,83	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,05	medium_impact	1,91	0,31	0,8	21,7	15,68	P	0,62	P	0,8	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4092	4092	G	C	MI.12397	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	786	262	K	N	aaG/aaC	6,65	1	0,01	probably_damaging	1	neutral	0,28	neutral	2,36	deleterious	-3,88	deleterious	-4,59	high_impact	3,55	neutral	0,75	damaging	0,12	deleterious	4,04	23,7	0,23	0,45	disease	0,55	disease	0,83	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,05	medium_impact	1,91	0,31	0,8	21,7	15,68	P	0,62	P	0,8	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4093	4093	A	G	MI.12398	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	787	263	T	A	Acc/Gcc	1,6	0,82	0,01	benign	0,01	neutral	0,49	neutral	2,82	neutral	-0,93	neutral	0	neutral_impact	0,66	neutral	0,84	neutral	0,93	neutral	-0,9	0,03	0,25	0,45	neutral	0,11	neutral	0,13	neutral	0,3	neutral	0,28	4	neutral	0,5	deleterious	0,74	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,27	medium_impact	-0,61	0,33	0,8	10,38	25,7	N	0,36	N	0,01	polymorphism	1	0,01	rs200180511	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4093	4093	A	T	MI.12399	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	787	263	T	S	Acc/Tcc	1,6	0,82	0,01	benign	0,17	neutral	0,5	neutral	2,77	neutral	-1,97	neutral	-1,02	low_impact	1,7	neutral	0,81	neutral	0,94	neutral	1,27	12,1	0,4	0,5	neutral	0,23	disease	0,55	neutral	0,33	neutral	0,45	1	neutral	0,4	deleterious	0,67	neutral	-6	neutral	0,23	medium_impact	-0,1	medium_impact	0,28	medium_impact	0,3	0,71	0,85	10,38	25,7	N	0,34	N	0,13	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8584	8584	G	T	MI.124	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	58	20	A	S	Gca/Tca	-5,89	0	0,17	benign	0,28	neutral	0,4	neutral	4,65	neutral	-0,84	neutral	-1,34	neutral_impact	0,48	neutral	0,88	neutral	0,71	neutral	1,75	14,7	0,36	0,65	neutral	0,35	neutral	0,35	neutral	0,3	neutral	0,47	1	neutral	0,52	deleterious	0,56	neutral	-6	neutral	0,28	medium_impact	-0,37	medium_impact	0,19	medium_impact	-0,69	0,66	0,9	24,78	23,03	N	0,36	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9109	9109	A	G	MI.1240	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	583	195	I	V	Att/Gtt	-8,43	0	0	benign	0	neutral	0,62	neutral	4,22	neutral	-0,81	neutral	-0,29	neutral_impact	0,06	neutral	0,97	neutral	0,93	neutral	-0,93	0,02	0,54	0,65	NA	NA	neutral	0,09	neutral	0,29	neutral	0,22	6	neutral	0,37	deleterious	0,81	neutral	-6	neutral	0,11	high_impact	2,09	medium_impact	0,41	low_impact	-1,05	0,44	0,9	20,35	25,84	N	0,37	N	0,61	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4093	4093	A	C	MI.12400	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	787	263	T	P	Acc/Ccc	1,6	0,82	0,01	possibly_damaging	0,64	neutral	0,29	neutral	2,68	deleterious	-3,93	deleterious	-2,77	medium_impact	3,42	neutral	0,62	neutral	0,33	neutral	1,74	14,61	0,06	0,35	disease	0,52	disease	0,9	disease	0,68	disease	0,78	6	neutral	0,75	neutral	0,33	NA	0	deleterious	0,59	medium_impact	-0,99	medium_impact	0,06	medium_impact	1,8	0,38	0,8	10,38	25,7	N	0,39	N	0,78	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4094	4094	C	T	MI.12401	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	788	263	T	I	aCc/aTc	-0,47	0	0	benign	0,37	neutral	0,75	neutral	2,8	neutral	-0,43	neutral	-2,12	low_impact	1,78	neutral	0,84	neutral	0,84	neutral	1,15	11,5	0,12	0,4	neutral	0,18	disease	0,64	neutral	0,33	neutral	0,46	1	neutral	0,26	deleterious	0,69	neutral	-6	neutral	0,36	medium_impact	-0,53	medium_impact	0,54	medium_impact	0,37	0,54	0,8	10,38	25,7	N	0,25	N	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4094	4094	C	A	MI.12402	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	788	263	T	N	aCc/aAc	-0,47	0	0	possibly_damaging	0,64	neutral	0,38	neutral	2,7	deleterious	-3,57	deleterious	-2,84	medium_impact	2,73	damaging	0,59	neutral	0,47	deleterious	1,91	15,62	0,28	0,45	neutral	0,44	disease	0,82	disease	0,57	disease	0,75	5	neutral	0,68	neutral	0,37	NA	0	deleterious	0,56	medium_impact	-0,99	medium_impact	0,16	medium_impact	1,2	0,64	0,8	10,38	25,7	N	0,34	N	0,55	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4094	4094	C	G	MI.12403	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	788	263	T	S	aCc/aGc	-0,47	0	0	benign	0,17	neutral	0,5	neutral	2,77	neutral	-1,97	neutral	-1,02	low_impact	1,7	neutral	0,81	neutral	0,94	neutral	1,57	13,71	0,4	0,5	neutral	0,23	disease	0,55	neutral	0,33	neutral	0,45	1	neutral	0,4	deleterious	0,67	neutral	-6	neutral	0,23	medium_impact	-0,1	medium_impact	0,28	medium_impact	0,3	0,71	0,85	10,38	25,7	N	0,34	N	0,13	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4096	4096	C	G	MI.12404	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	790	264	L	V	Cta/Gta	-11,96	0	0	benign	0,12	neutral	0,57	neutral	2,77	neutral	-1,05	neutral	-0,22	low_impact	1,25	neutral	0,82	neutral	0,67	neutral	1,52	13,41	0,29	0,45	neutral	0,14	neutral	0,18	neutral	0,21	neutral	0,33	3	neutral	0,33	deleterious	0,73	neutral	-6	neutral	0,13	medium_impact	0,06	medium_impact	0,34	medium_impact	-0,1	0,58	0,8	19,5	14,66	N	0,36	N	0,69	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4096	4096	C	A	MI.12405	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	790	264	L	M	Cta/Ata	-11,96	0	0	probably_damaging	0,96	neutral	0,27	neutral	2,67	neutral	-2,95	neutral	-0,08	low_impact	1,34	neutral	0,88	neutral	0,89	deleterious	2,55	19,82	0,23	0,45	neutral	0,37	neutral	0,16	neutral	0,2	neutral	0,3	4	neutral	0,96	neutral	0,16	neutral	-2	deleterious	0,64	low_impact	-2,05	medium_impact	0,03	medium_impact	-0,02	0,4	0,8	19,5	14,66	N	0,53	P	0,27	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4097	4097	T	C	MI.12406	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	791	264	L	P	cTa/cCa	-2,08	0	0	probably_damaging	0,98	neutral	0,24	neutral	2,64	deleterious	-4,57	neutral	-1,95	medium_impact	2,46	neutral	0,69	neutral	0,36	deleterious	3,92	23,5	0,04	0,35	disease	0,58	disease	0,81	disease	0,54	disease	0,76	5	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,83	low_impact	-2,34	medium_impact	-0,01	medium_impact	0,96	0,23	0,8	19,5	14,66	N	0,3	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4097	4097	T	A	MI.12407	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	791	264	L	Q	cTa/cAa	-2,08	0	0	probably_damaging	0,98	neutral	0,28	neutral	2,66	deleterious	-3,4	neutral	-1,45	medium_impact	2,88	neutral	0,74	neutral	0,45	deleterious	4,11	23,7	0,06	0,35	neutral	0,4	disease	0,55	neutral	0,39	neutral	0,49	0	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,7	low_impact	-2,34	medium_impact	0,05	medium_impact	1,33	0,27	0,8	19,5	14,66	N	0,42	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4097	4097	T	G	MI.12408	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	791	264	L	R	cTa/cGa	-2,08	0	0	probably_damaging	0,97	neutral	0,35	neutral	2,66	deleterious	-3,97	neutral	-1,64	medium_impact	3,43	neutral	0,73	neutral	0,43	deleterious	4,27	24	0,03	0,35	neutral	0,47	disease	0,79	disease	0,54	disease	0,75	5	neutral	0,97	neutral	0,19	deleterious	1	deleterious	0,78	low_impact	-2,17	medium_impact	0,12	medium_impact	1,81	0,18	0,8	19,5	14,66	N	0,37	N	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4099	4099	C	A	MI.12409	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	793	265	L	I	Ctt/Att	-8,05	0	0	benign	0,08	neutral	0,6	neutral	2,68	neutral	-0,64	neutral	-0,99	neutral_impact	0,74	neutral	0,86	neutral	0,93	deleterious	2,94	22	0,25	0,45	neutral	0,25	neutral	0,23	neutral	0,24	neutral	0,43	1	neutral	0,32	deleterious	0,76	neutral	-6	neutral	0,16	medium_impact	0,25	medium_impact	0,37	medium_impact	-0,54	0,39	0,8	24,21	16,02	N	0,35	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9109	9109	A	C	MI.1241	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	583	195	I	L	Att/Ctt	-8,43	0	0	benign	0,03	neutral	0,52	neutral	4,26	neutral	-0,59	neutral	-0,95	neutral_impact	-0,05	neutral	0,84	neutral	0,68	neutral	-0,28	0,73	0,29	0,65	NA	NA	neutral	0,23	neutral	0,23	neutral	0,2	6	neutral	0,44	deleterious	0,75	neutral	-6	neutral	0,13	medium_impact	0,68	medium_impact	0,31	low_impact	-1,14	0,51	0,9	20,35	25,84	N	0,34	N	0,23	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4099	4099	C	G	MI.12410	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	793	265	L	V	Ctt/Gtt	-8,05	0	0	benign	0,4	neutral	0,35	neutral	2,69	neutral	-0,39	neutral	-1,58	medium_impact	1,99	neutral	0,89	neutral	0,85	deleterious	3,48	23,1	0,19	0,45	neutral	0,21	neutral	0,41	neutral	0,3	neutral	0,46	1	neutral	0,59	deleterious	0,48	neutral	-3	neutral	0,28	medium_impact	-0,59	medium_impact	0,12	medium_impact	0,55	0,46	0,8	24,21	16,02	N	0,44	N	0,33	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4099	4099	C	T	MI.12411	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	793	265	L	F	Ctt/Ttt	-8,05	0	0	benign	0,08	neutral	0,59	neutral	2,69	neutral	-0,49	deleterious	-2,59	low_impact	0,95	neutral	0,87	neutral	0,91	deleterious	3,98	23,6	0,23	0,45	neutral	0,26	neutral	0,28	neutral	0,22	neutral	0,44	1	neutral	0,33	deleterious	0,76	neutral	-6	neutral	0,15	medium_impact	0,25	medium_impact	0,36	medium_impact	-0,36	0,37	0,8	24,21	16,02	N	0,37	N	0,05	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4100	4100	T	C	MI.12412	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	794	265	L	P	cTt/cCt	-4,38	0	0	probably_damaging	0,95	neutral	0,08	neutral	2,56	deleterious	-4,29	deleterious	-4,96	medium_impact	2,75	damaging	0,59	neutral	0,36	deleterious	4,05	23,7	0,04	0,35	disease	0,65	disease	0,85	disease	0,67	disease	0,72	4	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,83	low_impact	-1,95	medium_impact	-0,32	medium_impact	1,21	0,29	0,8	24,21	16,02	N	0,3	N	0,94	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4100	4100	T	G	MI.12413	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	794	265	L	R	cTt/cGt	-4,38	0	0	probably_damaging	0,93	neutral	0,24	neutral	2,57	deleterious	-3,65	deleterious	-4,29	medium_impact	3,44	neutral	0,65	neutral	0,4	deleterious	4,35	24,1	0,03	0,35	disease	0,55	disease	0,85	disease	0,66	disease	0,72	4	neutral	0,95	neutral	0,16	deleterious	1	deleterious	0,78	low_impact	-1,81	medium_impact	-0,01	medium_impact	1,82	0,22	0,8	24,21	16,02	N	0,34	N	0,91	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4100	4100	T	A	MI.12414	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	794	265	L	H	cTt/cAt	-4,38	0	0	probably_damaging	0,98	neutral	0,14	neutral	2,56	deleterious	-4,24	deleterious	-4,96	high_impact	3,79	neutral	0,71	neutral	0,45	deleterious	4,35	24,1	0,06	0,35	disease	0,64	disease	0,75	disease	0,62	disease	0,68	4	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,78	low_impact	-2,34	medium_impact	-0,17	high_impact	2,12	0,22	0,8	24,21	16,02	N	0,39	N	0,81	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4102	4102	C	G	MI.12415	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	796	266	L	V	Cta/Gta	-8,97	0	0	probably_damaging	1	neutral	0,48	neutral	2,52	neutral	-1,57	deleterious	-2,65	medium_impact	2,08	neutral	0,62	neutral	0,53	deleterious	3,52	23,1	0,2	0,45	neutral	0,2	neutral	0,45	neutral	0,3	neutral	0,43	1	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,26	medium_impact	0,63	0,43	0,8	55,97	9,68	N	0,36	N	0,84	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4102	4102	C	A	MI.12416	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	796	266	L	M	Cta/Ata	-8,97	0	0	probably_damaging	1	neutral	0,78	neutral	2,44	neutral	-2,5	neutral	-1,74	medium_impact	2,36	neutral	0,7	neutral	0,64	deleterious	3,82	23,4	0,17	0,45	neutral	0,36	neutral	0,43	neutral	0,28	neutral	0,45	1	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,58	medium_impact	0,87	0,3	0,8	55,97	9,68	N	0,3	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4103	4103	T	A	MI.12417	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	797	266	L	Q	cTa/cAa	-0,93	0	0	probably_damaging	1	neutral	0,09	neutral	2,37	deleterious	-4,42	deleterious	-5,36	high_impact	4,18	neutral	0,66	neutral	0,5	deleterious	4,08	23,7	0,05	0,35	disease	0,63	disease	0,79	disease	0,54	disease	0,68	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	-0,29	high_impact	2,46	0,2	0,8	55,97	9,68	N	0,42	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4103	4103	T	G	MI.12418	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	797	266	L	R	cTa/cGa	-0,93	0	0	probably_damaging	1	neutral	0,3	neutral	2,37	deleterious	-4,35	deleterious	-5,36	high_impact	4,18	neutral	0,67	neutral	0,45	deleterious	4,2	23,9	0,03	0,35	disease	0,61	disease	0,88	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,07	high_impact	2,46	0,24	0,8	55,97	9,68	N	0,4	N	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4103	4103	T	C	MI.12419	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	797	266	L	P	cTa/cCa	-0,93	0	0	probably_damaging	1	neutral	0,07	neutral	2,36	deleterious	-4,95	deleterious	-6,27	medium_impact	3,48	neutral	0,66	neutral	0,47	deleterious	3,96	23,6	0,03	0,35	disease	0,69	disease	0,84	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,86	low_impact	-3,57	medium_impact	-0,35	medium_impact	1,85	0,26	0,8	55,97	9,68	N	0,32	N	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9109	9109	A	T	MI.1242	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	583	195	I	F	Att/Ttt	-8,43	0	0	benign	0,36	neutral	0,16	neutral	4,01	deleterious	-3,52	deleterious	-2,94	low_impact	1,16	neutral	0,87	neutral	0,37	deleterious	2,43	19,04	0,32	0,65	NA	NA	disease	0,61	neutral	0,38	neutral	0,49	0	neutral	0,81	neutral	0,4	neutral	-6	neutral	0,4	medium_impact	-0,52	medium_impact	-0,12	medium_impact	-0,1	0,62	0,9	20,35	25,84	N	0,4	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4105	4105	A	G	MI.12420	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	799	267	T	A	Acc/Gcc	-5,75	0	0	possibly_damaging	0,53	neutral	0,54	neutral	2,81	neutral	0,55	neutral	-1,9	low_impact	1,39	neutral	0,71	neutral	0,6	deleterious	3,54	23,1	0,21	0,45	neutral	0,12	disease	0,53	neutral	0,3	neutral	0,44	1	neutral	0,5	deleterious	0,51	neutral	-3	neutral	0,37	medium_impact	-0,8	medium_impact	0,31	medium_impact	0,03	0,39	0,8	16,98	17,21	N	0,31	N	0,71	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4105	4105	A	T	MI.12421	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	799	267	T	S	Acc/Tcc	-5,75	0	0	benign	0,13	neutral	0,44	neutral	2,82	neutral	-0,49	neutral	-0,18	neutral_impact	-0,04	neutral	0,77	neutral	0,79	deleterious	0,83	9,64	0,28	0,45	neutral	0,16	neutral	0,11	neutral	0,22	neutral	0,28	4	neutral	0,48	deleterious	0,66	neutral	-6	neutral	0,15	medium_impact	0,02	medium_impact	0,22	low_impact	-1,22	0,47	0,8	16,98	17,21	N	0,4	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4105	4105	A	C	MI.12422	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	799	267	T	P	Acc/Ccc	-5,75	0	0	benign	0,08	neutral	0,22	neutral	2,72	neutral	-2,37	deleterious	-3,38	medium_impact	2,5	neutral	0,68	neutral	0,34	deleterious	3,58	23,2	0,05	0,35	neutral	0,47	disease	0,93	disease	0,64	disease	0,79	6	neutral	0,76	deleterious	0,57	neutral	-3	neutral	0,33	medium_impact	0,25	medium_impact	-0,03	medium_impact	1	0,28	0,8	16,98	17,21	N	0,34	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4106	4106	C	T	MI.12423	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	800	267	T	I	aCc/aTc	0,68	0,03	0	benign	0,11	neutral	0,42	neutral	2,86	neutral	1,25	deleterious	-3,69	low_impact	1,18	neutral	0,75	neutral	0,55	deleterious	4,01	23,6	0,13	0,4	neutral	0,16	disease	0,77	neutral	0,3	disease	0,51	0	neutral	0,51	deleterious	0,66	neutral	-6	neutral	0,2	medium_impact	0,1	medium_impact	0,2	medium_impact	-0,16	0,44	0,8	16,98	17,21	N	0,37	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4106	4106	C	A	MI.12424	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	800	267	T	N	aCc/aAc	0,68	0,03	0	possibly_damaging	0,76	neutral	0,3	neutral	2,73	neutral	-2,17	neutral	-2,08	medium_impact	2,61	neutral	0,61	neutral	0,42	deleterious	3,9	23,5	0,23	0,45	neutral	0,41	disease	0,87	disease	0,51	disease	0,71	4	neutral	0,81	neutral	0,27	NA	0	deleterious	0,7	low_impact	-1,22	medium_impact	0,07	medium_impact	1,09	0,45	0,8	16,98	17,21	N	0,41	N	0,72	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4106	4106	C	G	MI.12425	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	800	267	T	S	aCc/aGc	0,68	0,03	0	benign	0,13	neutral	0,44	neutral	2,82	neutral	-0,49	neutral	-0,18	neutral_impact	-0,04	neutral	0,77	neutral	0,79	neutral	1,02	10,76	0,28	0,45	neutral	0,16	neutral	0,11	neutral	0,22	neutral	0,28	4	neutral	0,48	deleterious	0,66	neutral	-6	neutral	0,15	medium_impact	0,02	medium_impact	0,22	low_impact	-1,22	0,47	0,8	16,98	17,21	N	0,43	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4108	4108	T	C	MI.12426	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	802	268	S	P	Tcc/Ccc	-9,66	0	0	possibly_damaging	0,55	neutral	0,2	neutral	2,72	neutral	-2,15	neutral	-1,53	medium_impact	2,27	neutral	0,63	neutral	0,4	deleterious	4,1	23,7	0,08	0,35	neutral	0,43	disease	0,83	disease	0,59	disease	0,79	6	neutral	0,79	neutral	0,33	NA	0	deleterious	0,66	medium_impact	-0,83	medium_impact	-0,06	medium_impact	0,79	0,3	0,8	25,16	28,89	N	0,34	N	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4108	4108	T	G	MI.12427	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	802	268	S	A	Tcc/Gcc	-9,66	0	0	benign	0,01	neutral	0,71	neutral	2,81	neutral	0,39	neutral	0,34	low_impact	0,96	neutral	0,85	neutral	0,97	deleterious	2,34	18,44	0,22	0,45	neutral	0,16	neutral	0,21	neutral	0,34	neutral	0,36	3	neutral	0,27	deleterious	0,85	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	0,49	medium_impact	-0,35	0,34	0,8	25,16	28,89	N	0,31	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4108	4108	T	A	MI.12428	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	802	268	S	T	Tcc/Acc	-9,66	0	0	benign	0,01	neutral	0,61	neutral	2,81	neutral	-0,37	neutral	0,39	neutral_impact	0,3	neutral	0,8	neutral	0,98	deleterious	2,29	18,11	0,24	0,45	neutral	0,16	neutral	0,15	neutral	0,25	neutral	0,29	4	neutral	0,37	deleterious	0,8	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	0,38	medium_impact	-0,93	0,33	0,8	25,16	28,89	N	0,34	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4109	4109	C	G	MI.12429	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	803	268	S	C	tCc/tGc	-0,7	0	0	possibly_damaging	0,84	neutral	0,16	neutral	2,72	neutral	-1,62	neutral	-0,59	low_impact	1,8	neutral	0,85	neutral	0,65	deleterious	3,72	23,3	0,08	0,35	neutral	0,31	disease	0,63	neutral	0,45	disease	0,5	0	neutral	0,92	neutral	0,16	neutral	-3	deleterious	0,57	low_impact	-1,43	medium_impact	-0,13	medium_impact	0,38	0,26	0,8	25,16	28,89	N	0,37	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9110	9110	T	C	MI.1243	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	584	195	I	T	aTt/aCt	-0,8	0	0,01	benign	0,19	neutral	0,16	neutral	4,02	deleterious	-3,21	deleterious	-2,61	low_impact	1,48	neutral	0,96	neutral	0,81	deleterious	0,51	7,48	0,35	0,65	NA	NA	neutral	0,32	neutral	0,37	neutral	0,17	7	neutral	0,81	deleterious	0,49	neutral	-6	neutral	0,2	medium_impact	-0,16	medium_impact	-0,12	medium_impact	0,17	0,65	0,9	20,35	25,84	N	0,45	N	1	polymorphism	1	0,07	.	.	.	.	.	MNGIE fibroblasts	.	.	.	.	.	.	.	.	.
chrM	4109	4109	C	A	MI.12430	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	803	268	S	Y	tCc/tAc	-0,7	0	0	possibly_damaging	0,79	neutral	1	neutral	2,76	neutral	-0,82	neutral	-1,01	low_impact	0,98	neutral	0,77	neutral	0,57	deleterious	4,16	23,8	0,08	0,35	neutral	0,29	disease	0,62	neutral	0,34	neutral	0,47	1	neutral	0,79	deleterious	0,61	neutral	-3	deleterious	0,58	low_impact	-1,29	high_impact	1,96	medium_impact	-0,33	0,28	0,8	25,16	28,89	N	0,21	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4109	4109	C	T	MI.12431	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	803	268	S	F	tCc/tTc	-0,7	0	0	possibly_damaging	0,47	neutral	0,92	neutral	2,91	neutral	2,14	neutral	-0,57	neutral_impact	-0,62	neutral	0,87	neutral	0,88	deleterious	3,21	22,7	0,1	0,4	neutral	0,15	neutral	0,29	neutral	0,3	neutral	0,42	2	neutral	0,39	deleterious	0,73	neutral	-3	deleterious	0,44	medium_impact	-0,7	medium_impact	0,87	low_impact	-1,73	0,15	0,8	25,16	28,89	N	0,32	N	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4111	4111	C	A	MI.12432	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	805	269	L	M	Ctg/Atg	-11,5	0	0	benign	0,4	neutral	0,23	neutral	2,64	neutral	-1,91	neutral	-0,4	low_impact	1,4	neutral	0,87	neutral	0,93	deleterious	2,56	19,86	0,23	0,45	neutral	0,4	neutral	0,15	neutral	0,28	neutral	0,31	4	neutral	0,73	neutral	0,42	neutral	-6	neutral	0,25	medium_impact	-0,59	medium_impact	-0,02	medium_impact	0,03	0,4	0,8	22,64	19,17	N	0,51	P	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4111	4111	C	G	MI.12433	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	805	269	L	V	Ctg/Gtg	-11,5	0	0	benign	0,4	neutral	0,5	neutral	2,77	neutral	-0,2	neutral	-0,23	low_impact	1,7	neutral	0,87	neutral	0,88	deleterious	1,91	15,67	0,19	0,45	neutral	0,13	neutral	0,13	neutral	0,27	neutral	0,27	5	neutral	0,44	deleterious	0,55	neutral	-6	neutral	0,23	medium_impact	-0,59	medium_impact	0,28	medium_impact	0,3	0,37	0,8	22,64	19,17	N	0,39	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4112	4112	T	C	MI.12434	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	806	269	L	P	cTg/cCg	-8,05	0	0	probably_damaging	0,95	neutral	0,2	neutral	2,57	deleterious	-4,01	deleterious	-2,96	high_impact	3,76	neutral	0,69	neutral	0,42	deleterious	3,98	23,6	0,05	0,35	disease	0,63	disease	0,8	disease	0,59	disease	0,73	5	neutral	0,97	neutral	0,13	deleterious	2	deleterious	0,8	low_impact	-1,95	medium_impact	-0,06	high_impact	2,1	0,24	0,8	22,64	19,17	N	0,39	N	0,79	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4112	4112	T	G	MI.12435	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	806	269	L	R	cTg/cGg	-8,05	0	0	probably_damaging	0,93	neutral	0,35	neutral	2,58	deleterious	-3,66	deleterious	-2,71	high_impact	3,76	neutral	0,73	neutral	0,5	deleterious	4,26	23,9	0,05	0,35	disease	0,54	disease	0,74	disease	0,58	disease	0,7	4	neutral	0,94	neutral	0,21	deleterious	2	deleterious	0,73	low_impact	-1,81	medium_impact	0,12	high_impact	2,1	0,15	0,8	22,64	19,17	N	0,4	N	0,48	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4112	4112	T	A	MI.12436	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	806	269	L	Q	cTg/cAg	-8,05	0	0	probably_damaging	0,93	neutral	0,29	neutral	2,58	deleterious	-3,88	deleterious	-2,5	high_impact	3,76	neutral	0,74	neutral	0,56	deleterious	4,27	23,9	0,08	0,35	disease	0,56	disease	0,58	neutral	0,44	neutral	0,48	0	neutral	0,94	neutral	0,18	deleterious	2	deleterious	0,68	low_impact	-1,81	medium_impact	0,06	high_impact	2,1	0,17	0,8	22,64	19,17	N	0,46	N	0,42	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4114	4114	T	C	MI.12437	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	808	270	F	L	Ttc/Ctc	-9,2	0	0	possibly_damaging	0,8	neutral	0,76	neutral	2,72	neutral	-1	deleterious	-5,37	medium_impact	2,73	neutral	0,67	damaging	0,16	deleterious	4,12	23,8	0,11	0,4	neutral	0,17	disease	0,79	disease	0,64	disease	0,68	4	neutral	0,77	deleterious	0,48	NA	0	deleterious	0,59	low_impact	-1,32	medium_impact	0,56	medium_impact	1,2	0,26	0,8	60,38	10,13	N	0,32	N	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4114	4114	T	A	MI.12438	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	808	270	F	I	Ttc/Atc	-9,2	0	0	probably_damaging	0,91	neutral	0,51	neutral	2,65	neutral	-1,11	deleterious	-5,37	medium_impact	2,27	neutral	0,72	damaging	0,2	deleterious	4,51	24,3	0,13	0,4	neutral	0,18	disease	0,75	disease	0,66	disease	0,68	4	neutral	0,9	neutral	0,3	deleterious	1	deleterious	0,68	low_impact	-1,69	medium_impact	0,29	medium_impact	0,79	0,24	0,8	60,38	10,13	N	0,29	N	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4114	4114	T	G	MI.12439	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	808	270	F	V	Ttc/Gtc	-9,2	0	0	possibly_damaging	0,88	neutral	0,59	neutral	2,67	neutral	-1,34	deleterious	-6,26	medium_impact	2,86	neutral	0,62	damaging	0,17	deleterious	4,16	23,8	0,11	0,4	neutral	0,19	disease	0,81	disease	0,67	disease	0,69	4	neutral	0,86	neutral	0,36	NA	0	deleterious	0,62	low_impact	-1,56	medium_impact	0,36	medium_impact	1,31	0,26	0,8	60,38	10,13	N	0,33	N	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9110	9110	T	A	MI.1244	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	584	195	I	N	aTt/aAt	-0,8	0	0,01	possibly_damaging	0,78	deleterious	0	neutral	3,98	deleterious	-4,87	deleterious	-4,79	medium_impact	3,29	neutral	0,84	neutral	0,36	deleterious	4,41	24,1	0,24	0,65	NA	NA	disease	0,65	disease	0,57	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	4	deleterious	0,62	low_impact	-1,28	low_impact	-1,4	medium_impact	1,72	0,55	0,9	20,35	25,84	N	0,39	N	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4115	4115	T	A	MI.12440	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	809	270	F	Y	tTc/tAc	7,34	1	0	probably_damaging	0,92	neutral	0,96	neutral	2,63	neutral	-2,3	deleterious	-2,68	medium_impact	2,69	neutral	0,69	damaging	0,17	deleterious	4,4	24,1	0,17	0,45	neutral	0,35	disease	0,69	disease	0,63	disease	0,5	0	neutral	0,92	deleterious	0,52	deleterious	1	deleterious	0,7	low_impact	-1,75	medium_impact	1,05	medium_impact	1,16	0,37	0,8	60,38	10,13	N	0,53	P	0,88	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4115	4115	T	G	MI.12441	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	809	270	F	C	tTc/tGc	7,34	1	0	probably_damaging	0,98	neutral	0,17	neutral	2,57	deleterious	-4,27	deleterious	-7,16	high_impact	4,18	neutral	0,69	damaging	0,16	deleterious	4,21	23,9	0,08	0,35	disease	0,58	disease	0,82	disease	0,69	disease	0,71	4	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,75	low_impact	-2,34	medium_impact	-0,11	high_impact	2,46	0,14	0,8	60,38	10,13	P	0,63	P	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4115	4115	T	C	MI.12442	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	809	270	F	S	tTc/tCc	7,34	1	0	benign	0,2	neutral	0,45	neutral	2,65	neutral	-2,12	deleterious	-7,15	medium_impact	3,49	neutral	0,71	damaging	0,22	deleterious	4,35	24,1	0,06	0,35	neutral	0,3	disease	0,82	disease	0,63	disease	0,68	4	neutral	0,46	deleterious	0,63	neutral	-3	neutral	0,3	medium_impact	-0,19	medium_impact	0,23	medium_impact	1,86	0,26	0,8	60,38	10,13	P	0,59	P	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4116	4116	C	G	MI.12443	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	810	270	F	L	ttC/ttG	7,34	1	0	possibly_damaging	0,8	neutral	0,76	neutral	2,72	neutral	-1	deleterious	-5,37	medium_impact	2,73	neutral	0,67	damaging	0,16	deleterious	4,47	24,2	0,11	0,4	neutral	0,17	disease	0,79	disease	0,64	disease	0,68	4	neutral	0,77	deleterious	0,48	NA	0	deleterious	0,59	low_impact	-1,32	medium_impact	0,56	medium_impact	1,2	0,26	0,8	60,38	10,13	P	0,52	P	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4116	4116	C	A	MI.12444	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	810	270	F	L	ttC/ttA	7,34	1	0	possibly_damaging	0,8	neutral	0,76	neutral	2,72	neutral	-1	deleterious	-5,37	medium_impact	2,73	neutral	0,67	damaging	0,16	deleterious	4,76	24,7	0,11	0,4	neutral	0,17	disease	0,79	disease	0,64	disease	0,68	4	neutral	0,77	deleterious	0,48	NA	0	deleterious	0,59	low_impact	-1,32	medium_impact	0,56	medium_impact	1,2	0,26	0,8	60,38	10,13	P	0,53	P	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4117	4117	T	A	MI.12445	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	811	271	L	M	Tta/Ata	-0,93	0	0,04	probably_damaging	1	neutral	0,13	neutral	2,55	neutral	-2,69	neutral	-1,75	low_impact	1,88	neutral	0,77	damaging	0,16	deleterious	3,64	23,2	0,26	0,45	neutral	0,34	disease	0,55	disease	0,56	disease	0,63	3	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,69	low_impact	-3,57	medium_impact	-0,19	medium_impact	0,45	0,43	0,8	60,06	10,49	N	0,28	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4117	4117	T	G	MI.12446	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	811	271	L	V	Tta/Gta	-0,93	0	0,04	probably_damaging	1	neutral	0,22	neutral	2,83	neutral	0,14	deleterious	-2,56	low_impact	1,94	neutral	0,68	damaging	0,15	deleterious	3,47	23	0,19	0,45	neutral	0,15	neutral	0,48	neutral	0,35	neutral	0,42	2	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,68	low_impact	-3,57	medium_impact	-0,03	medium_impact	0,51	0,34	0,8	60,06	10,49	N	0,32	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4118	4118	T	C	MI.12447	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	812	271	L	S	tTa/tCa	-0,47	0	0	probably_damaging	1	neutral	0,15	neutral	2,54	deleterious	-3,3	deleterious	-5,29	high_impact	3,79	neutral	0,73	damaging	0,15	deleterious	3,89	23,5	0,08	0,35	neutral	0,31	disease	0,74	disease	0,59	disease	0,67	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,74	low_impact	-3,57	medium_impact	-0,15	high_impact	2,12	0,23	0,8	60,06	10,49	N	0,32	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	COSM1155627	.	.	.	.	.	.	.	.
chrM	4118	4118	T	G	MI.12448	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	812	271	L	W	tTa/tGa	-0,47	0	0	probably_damaging	1	neutral	0,23	neutral	2,51	deleterious	-5,66	deleterious	-5,33	high_impact	4,13	neutral	0,74	damaging	0,13	deleterious	3,9	23,5	0,06	0,35	disease	0,72	disease	0,8	disease	0,61	disease	0,68	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	-0,02	high_impact	2,42	0,19	0,8	60,06	10,49	N	0,34	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4119	4119	A	C	MI.12449	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	813	271	L	F	ttA/ttC	7,34	1	0	probably_damaging	1	neutral	0,41	neutral	2,54	neutral	-2,94	deleterious	-3,52	medium_impact	2,71	neutral	0,7	damaging	0,12	deleterious	3,71	23,3	0,19	0,45	neutral	0,39	disease	0,69	disease	0,59	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	0,19	medium_impact	1,18	0,37	0,8	60,06	10,49	P	0,56	P	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9110	9110	T	G	MI.1245	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	584	195	I	S	aTt/aGt	-0,8	0	0,01	possibly_damaging	0,44	neutral	0,05	neutral	4,03	neutral	-2,99	deleterious	-3,75	medium_impact	2,1	neutral	0,81	neutral	0,42	deleterious	2,71	20,9	0,27	0,65	NA	NA	disease	0,63	disease	0,56	disease	0,62	2	neutral	0,94	neutral	0,31	NA	0	neutral	0,3	medium_impact	-0,66	medium_impact	-0,43	medium_impact	0,7	0,58	0,9	20,35	25,84	N	0,34	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4119	4119	A	T	MI.12450	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	813	271	L	F	ttA/ttT	7,34	1	0	probably_damaging	1	neutral	0,41	neutral	2,54	neutral	-2,94	deleterious	-3,52	medium_impact	2,71	neutral	0,7	damaging	0,12	deleterious	3,72	23,3	0,19	0,45	neutral	0,39	disease	0,69	disease	0,59	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	0,19	medium_impact	1,18	0,37	0,8	60,06	10,49	P	0,57	P	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4120	4120	T	C	MI.12451	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	814	272	W	R	Tga/Cga	0,45	0,99	0	probably_damaging	0,96	neutral	0,43	neutral	2,66	deleterious	-3,94	deleterious	-12,58	high_impact	4,07	neutral	0,71	damaging	0,08	deleterious	3,71	23,3	0,04	0,35	neutral	0,49	disease	0,89	disease	0,77	disease	0,78	6	neutral	0,95	neutral	0,24	deleterious	2	deleterious	0,76	low_impact	-2,05	medium_impact	0,21	high_impact	2,37	0,06	0,8	58,81	10,42	P	0,55	P	0,98	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4120	4120	T	G	MI.12452	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	814	272	W	G	Tga/Gga	0,45	0,99	0	probably_damaging	0,91	neutral	0,39	neutral	2,65	deleterious	-3,83	deleterious	-11,68	high_impact	4,07	neutral	0,73	damaging	0,13	deleterious	4,02	23,6	0,05	0,35	neutral	0,42	disease	0,86	disease	0,74	disease	0,74	5	neutral	0,91	neutral	0,24	deleterious	2	deleterious	0,72	low_impact	-1,69	medium_impact	0,17	high_impact	2,37	0,07	0,8	58,81	10,42	N	0,49	N	1	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4121	4121	G	C	MI.12453	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	815	272	W	S	tGa/tCa	7,34	1	0	probably_damaging	0,96	neutral	0,53	neutral	2,68	neutral	-2,98	deleterious	-12,58	high_impact	4,07	neutral	0,71	damaging	0,13	deleterious	4,14	23,8	0,06	0,35	neutral	0,27	disease	0,88	disease	0,72	disease	0,74	5	neutral	0,95	neutral	0,29	deleterious	2	deleterious	0,73	low_impact	-2,05	medium_impact	0,3	high_impact	2,37	0,05	0,8	58,81	10,42	N	0,51	P	0,99	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4121	4121	G	T	MI.12454	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	815	272	W	L	tGa/tTa	7,34	1	0	possibly_damaging	0,48	neutral	1	neutral	2,89	neutral	-0,75	deleterious	-11,69	medium_impact	2,73	neutral	0,69	damaging	0,09	deleterious	4,34	24	0,09	0,4	neutral	0,15	disease	0,85	disease	0,68	disease	0,66	3	neutral	0,48	deleterious	0,76	NA	0	deleterious	0,43	medium_impact	-0,72	high_impact	1,96	medium_impact	1,2	0,06	0,8	58,81	10,42	N	0,45	N	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4122	4122	A	C	MI.12455	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	816	272	W	C	tgA/tgC	7,11	1	0	probably_damaging	0,98	neutral	0,17	neutral	2,65	deleterious	-4,32	deleterious	-11,69	high_impact	3,72	neutral	0,7	damaging	0,08	deleterious	4,11	23,8	0,05	0,35	disease	0,59	disease	0,87	disease	0,74	disease	0,77	5	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,78	low_impact	-2,34	medium_impact	-0,11	high_impact	2,06	0,09	0,8	58,81	10,42	P	0,58	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4122	4122	A	T	MI.12456	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	816	272	W	C	tgA/tgT	7,11	1	0	probably_damaging	0,98	neutral	0,17	neutral	2,65	deleterious	-4,32	deleterious	-11,69	high_impact	3,72	neutral	0,7	damaging	0,08	deleterious	4,23	23,9	0,05	0,35	disease	0,59	disease	0,87	disease	0,74	disease	0,77	5	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,78	low_impact	-2,34	medium_impact	-0,11	high_impact	2,06	0,09	0,8	58,81	10,42	P	0,59	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4123	4123	A	T	MI.12457	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	817	273	I	F	Att/Ttt	0,45	0,1	0	possibly_damaging	0,75	neutral	0,72	neutral	2,47	deleterious	-3,33	deleterious	-3,27	medium_impact	2,15	neutral	0,7	neutral	0,36	deleterious	3,97	23,6	0,12	0,4	neutral	0,25	disease	0,78	neutral	0,47	disease	0,63	3	neutral	0,7	deleterious	0,49	NA	0	deleterious	0,6	low_impact	-1,2	medium_impact	0,51	medium_impact	0,69	0,68	0,85	17,3	12,04	N	0,33	N	0,92	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	A4123T	LHON (putative)	+	-	Reported	1
chrM	4123	4123	A	C	MI.12458	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	817	273	I	L	Att/Ctt	0,45	0,1	0	benign	0,17	neutral	0,85	neutral	2,61	neutral	-1,11	neutral	-1,59	medium_impact	2	neutral	0,7	neutral	0,41	deleterious	3,9	23,5	0,25	0,45	neutral	0,17	disease	0,7	neutral	0,5	disease	0,53	1	neutral	0,08	deleterious	0,84	neutral	-3	neutral	0,2	medium_impact	-0,1	medium_impact	0,7	medium_impact	0,56	0,56	0,8	17,3	12,04	N	0,31	N	0,54	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4123	4123	A	G	MI.12459	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	817	273	I	V	Att/Gtt	0,45	0,1	0	benign	0,01	neutral	0,73	neutral	2,9	neutral	0,36	neutral	0,26	neutral_impact	-0,17	neutral	0,81	neutral	0,96	deleterious	0,43	6,87	0,5	0,6	neutral	0,15	neutral	0,04	neutral	0,2	neutral	0,24	5	neutral	0,24	deleterious	0,86	neutral	-6	neutral	0,08	medium_impact	1,12	medium_impact	0,52	low_impact	-1,34	0,53	0,8	17,3	12,04	N	0,39	N	0,04	polymorphism	1	0,01	rs200764459	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9111	9111	T	G	MI.1246	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	585	195	I	M	atT/atG	5,68	0,9	0	possibly_damaging	0,63	deleterious	0,03	neutral	4,09	neutral	-1,88	neutral	-1,66	low_impact	1,68	neutral	0,86	neutral	0,43	deleterious	3,12	22,6	0,34	0,65	NA	NA	neutral	0,35	neutral	0,35	neutral	0,18	6	neutral	0,97	neutral	0,2	deleterious	1	neutral	0,4	medium_impact	-0,98	medium_impact	-0,56	medium_impact	0,34	0,68	0,9	20,35	25,84	N	0,49	N	0,79	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4124	4124	T	C	MI.12460	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	818	273	I	T	aTt/aCt	-0,24	0,06	0	benign	0,03	neutral	0,42	neutral	2,52	neutral	-2,12	deleterious	-2,59	medium_impact	2,19	neutral	0,73	neutral	0,67	deleterious	2,46	19,21	0,08	0,35	neutral	0,29	disease	0,53	neutral	0,48	neutral	0,48	0	neutral	0,56	deleterious	0,7	neutral	-3	neutral	0,15	medium_impact	0,67	medium_impact	0,2	medium_impact	0,72	0,39	0,8	17,3	12,04	N	0,43	N	0,94	polymorphism	1	0,1	.	.	.	.	.	.	COSM1155629	.	.	.	.	.	.	.	.
chrM	4124	4124	T	A	MI.12461	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	818	273	I	N	aTt/aAt	-0,24	0,06	0	benign	0,04	neutral	0,27	neutral	2,44	deleterious	-4,57	deleterious	-5,04	medium_impact	3,45	neutral	0,72	neutral	0,43	deleterious	4,7	24,6	0,13	0,4	disease	0,59	disease	0,9	disease	0,55	disease	0,76	5	neutral	0,71	deleterious	0,62	neutral	-3	neutral	0,28	medium_impact	0,55	medium_impact	0,03	medium_impact	1,82	0,41	0,8	17,3	12,04	N	0,37	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4124	4124	T	G	MI.12462	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	818	273	I	S	aTt/aGt	-0,24	0,06	0	possibly_damaging	0,48	neutral	0,57	neutral	2,46	deleterious	-3,53	deleterious	-4,09	medium_impact	2,38	neutral	0,69	neutral	0,42	deleterious	4,49	24,3	0,05	0,35	neutral	0,4	disease	0,81	disease	0,54	disease	0,74	5	neutral	0,44	deleterious	0,55	NA	0	neutral	0,42	medium_impact	-0,72	medium_impact	0,34	medium_impact	0,89	0,34	0,8	17,3	12,04	N	0,28	N	0,94	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4125	4125	T	A	MI.12463	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	819	273	I	M	atT/atA	4,58	0,68	0	possibly_damaging	0,87	neutral	0,27	neutral	2,49	neutral	-2,63	neutral	-1,9	medium_impact	2,52	neutral	0,69	neutral	0,38	deleterious	3,76	23,3	0,22	0,45	neutral	0,33	disease	0,63	neutral	0,45	disease	0,52	0	neutral	0,9	neutral	0,2	NA	0	deleterious	0,59	low_impact	-1,53	medium_impact	0,03	medium_impact	1,01	0,61	0,8	17,3	12,04	N	0,48	N	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4125	4125	T	G	MI.12464	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	819	273	I	M	atT/atG	4,58	0,68	0	possibly_damaging	0,87	neutral	0,27	neutral	2,49	neutral	-2,63	neutral	-1,9	medium_impact	2,52	neutral	0,69	neutral	0,38	deleterious	3,58	23,2	0,22	0,45	neutral	0,33	disease	0,63	neutral	0,45	disease	0,52	0	neutral	0,9	neutral	0,2	NA	0	deleterious	0,59	low_impact	-1,53	medium_impact	0,03	medium_impact	1,01	0,61	0,8	17,3	12,04	N	0,47	N	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4126	4126	C	G	MI.12465	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	820	274	R	G	Cga/Gga	-9,43	0	0	possibly_damaging	0,74	neutral	0,35	neutral	2,12	deleterious	-4,86	deleterious	-6,29	high_impact	4,75	damaging	0,43	damaging	0,07	deleterious	4,32	24	0,03	0,35	disease	0,53	disease	0,83	disease	0,74	disease	0,75	5	neutral	0,78	neutral	0,31	deleterious	1	deleterious	0,65	low_impact	-1,18	medium_impact	0,12	high_impact	2,96	0,19	0,8	60,06	10,36	P	0,53	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4126	4126	C	T	MI.12466	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	820	274	R	W	Cga/Tga	-9,43	0	0	probably_damaging	0,99	neutral	0,26	neutral	2,09	deleterious	-7,39	deleterious	-7,19	high_impact	4,21	damaging	0,48	damaging	0,04	deleterious	5,27	25,7	0,05	0,35	disease	0,87	disease	0,91	disease	0,75	disease	0,84	7	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,85	low_impact	-2,62	medium_impact	0,02	high_impact	2,49	0,64	0,8	60,06	10,36	N	0,36	N	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4127	4127	G	A	MI.12467	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	821	274	R	Q	cGa/cAa	4,35	0,99	0	probably_damaging	0,91	neutral	0,28	neutral	2,17	deleterious	-3,45	deleterious	-3,59	high_impact	4,41	damaging	0,34	damaging	0,04	deleterious	4,63	24,5	0,12	0,4	neutral	0,37	disease	0,82	disease	0,76	disease	0,75	5	neutral	0,93	neutral	0,19	deleterious	2	deleterious	0,73	low_impact	-1,69	medium_impact	0,05	high_impact	2,66	0,85	0,9	60,06	10,36	P	0,76	P	1	polymorphism	0,96	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4127	4127	G	T	MI.12468	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	821	274	R	L	cGa/cTa	4,35	0,99	0	possibly_damaging	0,88	neutral	0,87	neutral	2,13	deleterious	-4,46	deleterious	-6,29	high_impact	4,75	damaging	0,45	damaging	0,04	deleterious	4,42	24,2	0,03	0,35	neutral	0,5	disease	0,93	disease	0,73	disease	0,82	6	neutral	0,86	deleterious	0,5	deleterious	1	deleterious	0,75	low_impact	-1,56	medium_impact	0,74	high_impact	2,96	0,05	0,8	60,06	10,36	P	0,66	P	1	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4127	4127	G	C	MI.12469	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	821	274	R	P	cGa/cCa	4,35	0,99	0	probably_damaging	0,96	neutral	0,23	neutral	2,11	deleterious	-5,41	deleterious	-6,27	high_impact	4,75	damaging	0,49	damaging	0,05	deleterious	4,31	24	0,02	0,35	disease	0,62	disease	0,87	disease	0,83	disease	0,8	6	neutral	0,97	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-2,05	medium_impact	-0,02	high_impact	2,96	0,13	0,8	60,06	10,36	P	0,7	P	1	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9111	9111	T	A	MI.1247	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	585	195	I	M	atT/atA	5,68	0,9	0	possibly_damaging	0,63	deleterious	0,03	neutral	4,09	neutral	-1,88	neutral	-1,66	low_impact	1,68	neutral	0,86	neutral	0,43	deleterious	3,44	23	0,34	0,65	NA	NA	neutral	0,35	neutral	0,35	neutral	0,18	6	neutral	0,97	neutral	0,2	deleterious	1	neutral	0,4	medium_impact	-0,98	medium_impact	-0,56	medium_impact	0,34	0,68	0,9	20,35	25,84	N	0,49	N	0,79	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4129	4129	A	G	MI.12470	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	823	275	T	A	Aca/Gca	-0,24	0,65	0,01	benign	0,01	neutral	0,57	neutral	3	neutral	1,44	neutral	2,99	neutral_impact	-2,74	neutral	0,65	neutral	0,82	neutral	-1,04	0,01	0,17	0,45	neutral	0,15	neutral	0,05	neutral	0,15	neutral	0,23	5	neutral	0,42	deleterious	0,78	neutral	-6	neutral	0,12	medium_impact	1,12	medium_impact	0,34	low_impact	-3,58	0,35	0,8	17,61	21,08	N	0,35	N	0	polymorphism	1	0,01	rs201832206	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4129	4129	A	C	MI.12471	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	823	275	T	P	Aca/Cca	-0,24	0,65	0,01	possibly_damaging	0,65	neutral	0,24	neutral	2,74	neutral	-2,43	neutral	-1,23	neutral_impact	0,76	damaging	0,56	neutral	0,46	deleterious	1,87	15,43	0,04	0,35	neutral	0,38	disease	0,86	disease	0,61	disease	0,78	6	neutral	0,79	neutral	0,3	neutral	-3	deleterious	0,64	low_impact	-1	medium_impact	-0,01	medium_impact	-0,53	0,23	0,8	17,61	21,08	N	0,34	N	0,3	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4129	4129	A	T	MI.12472	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	823	275	T	S	Aca/Tca	-0,24	0,65	0,01	benign	0,03	neutral	0,47	neutral	2,85	neutral	0,12	neutral	0,56	neutral_impact	-0,34	neutral	0,68	neutral	0,79	neutral	1,48	13,22	0,25	0,45	neutral	0,11	neutral	0,45	neutral	0,29	neutral	0,43	1	neutral	0,5	deleterious	0,72	neutral	-6	neutral	0,18	medium_impact	0,67	medium_impact	0,25	low_impact	-1,49	0,68	0,85	17,61	21,08	N	0,33	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4130	4130	C	A	MI.12473	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	824	275	T	K	aCa/aAa	5,04	1	0	benign	0,36	neutral	0,29	neutral	2,79	neutral	-0,57	neutral	-1,23	low_impact	1,3	neutral	0,62	neutral	0,56	deleterious	2,73	21	0,08	0,35	neutral	0,18	disease	0,72	disease	0,58	disease	0,67	3	neutral	0,65	neutral	0,47	neutral	-6	neutral	0,4	medium_impact	-0,52	medium_impact	0,06	medium_impact	-0,05	0,46	0,8	17,61	21,08	P	0,59	P	0,42	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4130	4130	C	T	MI.12474	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	824	275	T	M	aCa/aTa	5,04	1	0	possibly_damaging	0,89	neutral	0,24	neutral	2,75	neutral	-1,85	neutral	-1,23	low_impact	1,1	neutral	0,63	neutral	0,54	deleterious	3,74	23,3	0,08	0,35	neutral	0,31	disease	0,59	neutral	0,49	neutral	0,49	0	neutral	0,92	neutral	0,18	neutral	-3	deleterious	0,68	low_impact	-1,6	medium_impact	-0,01	medium_impact	-0,23	0,57	0,8	17,61	21,08	P	0,61	P	0,43	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4132	4132	G	C	MI.12475	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	826	276	A	P	Gca/Cca	-1,39	0	0	benign	0,36	neutral	0,23	neutral	2,65	deleterious	-3,27	neutral	-1,88	medium_impact	2,7	damaging	0,53	neutral	0,41	deleterious	2,13	17,07	0,04	0,35	disease	0,53	disease	0,84	neutral	0,49	disease	0,77	5	neutral	0,73	neutral	0,44	neutral	-3	deleterious	0,46	medium_impact	-0,52	medium_impact	-0,02	medium_impact	1,17	0,53	0,8	24,53	38,18	N	0,4	N	0,79	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4132	4132	G	A	MI.12476	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	826	276	A	T	Gca/Aca	-1,39	0	0	benign	0	neutral	0,41	neutral	2,86	neutral	1,33	neutral	-0,08	neutral_impact	-0,34	neutral	0,69	neutral	0,8	deleterious	2,37	18,62	0,15	0,4	neutral	0,14	neutral	0,14	neutral	0,17	neutral	0,27	5	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,19	low_impact	-1,49	0,48	0,8	24,53	38,18	P	0,58	P	0,04	polymorphism	1	0,01	rs1057520201	.	.	.	.	.	.	CPD	8,31	G4132A	NAION-associated	+	-	Reported	1
chrM	4132	4132	G	T	MI.12477	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	826	276	A	S	Gca/Tca	-1,39	0	0	benign	0	neutral	0,44	neutral	2,87	neutral	-0,1	neutral	2,49	neutral_impact	-1,47	neutral	0,66	neutral	0,81	neutral	-0,82	0,04	0,2	0,45	neutral	0,12	neutral	0,03	neutral	0,12	neutral	0,23	5	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,22	low_impact	-2,47	0,46	0,8	24,53	38,18	N	0,52	P	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4133	4133	C	G	MI.12478	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	827	276	A	G	gCa/gGa	2,52	0,99	0	benign	0,1	neutral	0,35	neutral	2,68	neutral	-2,73	neutral	-1	medium_impact	2	damaging	0,56	neutral	0,62	deleterious	2,12	16,95	0,16	0,45	neutral	0,24	disease	0,54	neutral	0,47	disease	0,51	0	neutral	0,6	deleterious	0,63	neutral	-3	neutral	0,2	medium_impact	0,15	medium_impact	0,12	medium_impact	0,56	0,62	0,8	24,53	38,18	P	0,57	P	0,34	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4133	4133	C	A	MI.12479	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	827	276	A	E	gCa/gAa	2,52	0,99	0	benign	0,15	neutral	0,26	neutral	2,7	neutral	-2,41	neutral	-1,02	medium_impact	2,35	neutral	0,6	neutral	0,59	deleterious	2,8	21,4	0,04	0,35	neutral	0,4	disease	0,76	disease	0,63	disease	0,74	5	neutral	0,7	deleterious	0,56	neutral	-3	neutral	0,32	medium_impact	-0,04	medium_impact	0,02	medium_impact	0,86	0,3	0,8	24,53	38,18	N	0,52	P	0,63	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9112	9112	C	G	MI.1248	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	586	196	L	V	Cta/Gta	-11,44	0	0	probably_damaging	0,99	neutral	0,21	neutral	4,43	neutral	-0,99	neutral	-2,21	low_impact	1,89	neutral	0,77	neutral	0,44	deleterious	3,44	23	0,32	0,65	NA	NA	neutral	0,49	disease	0,53	neutral	0,43	1	deleterious	0,99	neutral	0,11	neutral	-2	deleterious	0,79	low_impact	-2,65	medium_impact	-0,03	medium_impact	0,52	0,51	0,9	20,8	18,46	N	0,34	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4133	4133	C	T	MI.12480	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	827	276	A	V	gCa/gTa	2,52	0,99	0	benign	0,1	neutral	0,5	neutral	2,71	neutral	0,1	deleterious	-2,7	low_impact	1,42	damaging	0,56	neutral	0,76	deleterious	2,62	20,3	0,11	0,4	neutral	0,27	disease	0,55	neutral	0,5	disease	0,5	0	neutral	0,43	deleterious	0,7	neutral	-6	neutral	0,23	medium_impact	0,15	medium_impact	0,28	medium_impact	0,05	0,56	0,8	24,53	38,18	P	0,51	P	0,76	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4135	4135	T	C	MI.12481	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	829	277	Y	H	Tac/Cac	-14,26	0	0	probably_damaging	0,98	neutral	0,43	neutral	2,62	deleterious	-3,23	deleterious	-4,47	high_impact	4,04	damaging	0,56	neutral	0,32	deleterious	3,73	23,3	0,11	0,4	disease	0,64	disease	0,83	disease	0,8	disease	0,81	6	neutral	0,98	neutral	0,23	deleterious	2	deleterious	0,79	low_impact	-2,34	medium_impact	0,21	high_impact	2,34	0,13	0,8	60,06	10	N	0,38	N	1	polymorphism	1	0,18	rs876661355	Uncertain significance	not_specified	RCV000223794.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	4135	4135	T	A	MI.12482	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	829	277	Y	N	Tac/Aac	-14,26	0	0	probably_damaging	0,97	neutral	0,24	neutral	2,62	deleterious	-3,09	deleterious	-8,06	high_impact	3,7	neutral	0,69	neutral	0,4	deleterious	4,19	23,9	0,09	0,35	disease	0,62	disease	0,89	disease	0,72	disease	0,78	6	neutral	0,98	neutral	0,14	deleterious	2	deleterious	0,8	low_impact	-2,17	medium_impact	-0,01	high_impact	2,04	0,1	0,8	60,06	10	N	0,41	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4135	4135	T	G	MI.12483	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	829	277	Y	D	Tac/Gac	-14,26	0	0	probably_damaging	0,98	neutral	0,23	neutral	2,61	deleterious	-3,71	deleterious	-8,95	high_impact	4,04	neutral	0,71	neutral	0,36	deleterious	4,16	23,8	0,05	0,35	disease	0,73	disease	0,9	disease	0,79	disease	0,82	6	deleterious	0,98	neutral	0,13	deleterious	2	deleterious	0,82	low_impact	-2,34	medium_impact	-0,02	high_impact	2,34	0,09	0,8	60,06	10	N	0,48	N	1	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4136	4136	A	T	MI.12484	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	830	277	Y	F	tAc/tTc	7,34	1	0,01	possibly_damaging	0,74	neutral	0,78	neutral	2,71	neutral	-0,91	deleterious	-3,56	low_impact	1,59	neutral	0,65	neutral	0,45	deleterious	3,45	23	0,21	0,45	neutral	0,2	disease	0,69	disease	0,51	neutral	0,48	0	neutral	0,69	deleterious	0,52	neutral	-3	deleterious	0,62	low_impact	-1,18	medium_impact	0,58	medium_impact	0,2	0,33	0,8	60,06	10	P	0,55	P	0,8	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4136	4136	A	G	MI.12485	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	830	277	Y	C	tAc/tGc	7,34	1	0,01	probably_damaging	0,98	neutral	0,14	neutral	2,61	deleterious	-3,59	deleterious	-8,05	high_impact	4,04	neutral	0,83	neutral	0,37	deleterious	3,57	23,2	0,05	0,35	disease	0,64	disease	0,89	disease	0,74	disease	0,79	6	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,76	low_impact	-2,34	medium_impact	-0,17	high_impact	2,34	0,03	0,8	60,06	10	P	0,71	P	1	disease_causing_automatic	0	0,15	rs199476121	Pathogenic	Leber's_optic_atrophy	RCV000010378.2	MedGen:OMIM:SNOMED_CT	.	.	.	0,15	A4136G	LHON	+	-	Possibly synergistic	10
chrM	4136	4136	A	C	MI.12486	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	830	277	Y	S	tAc/tCc	7,34	1	0,01	probably_damaging	0,94	neutral	0,4	neutral	2,65	neutral	-2,12	deleterious	-8,05	high_impact	3,7	neutral	0,7	neutral	0,5	deleterious	3,74	23,3	0,06	0,35	neutral	0,45	disease	0,85	disease	0,71	disease	0,76	5	neutral	0,94	neutral	0,23	deleterious	2	deleterious	0,77	low_impact	-1,87	medium_impact	0,18	high_impact	2,04	0,19	0,8	60,06	10	P	0,66	P	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4138	4138	C	A	MI.12487	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	832	278	P	T	Ccc/Acc	-0,93	0,02	0	probably_damaging	1	neutral	0,39	neutral	1,19	deleterious	-6,45	deleterious	-7,18	high_impact	4,42	damaging	0,55	damaging	0,07	deleterious	3,95	23,6	0,05	0,35	disease	0,53	disease	0,83	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,17	high_impact	2,67	0,41	0,8	60,06	10,39	N	0,37	N	0,91	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4138	4138	C	G	MI.12488	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	832	278	P	A	Ccc/Gcc	-0,93	0,02	0	probably_damaging	1	neutral	0,51	neutral	1,22	deleterious	-5,75	deleterious	-7,18	high_impact	4,07	damaging	0,58	damaging	0,1	deleterious	3,2	22,7	0,06	0,35	neutral	0,27	disease	0,76	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,74	low_impact	-3,57	medium_impact	0,29	high_impact	2,37	0,48	0,8	60,06	10,39	N	0,32	N	0,78	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4138	4138	C	T	MI.12489	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	832	278	P	S	Ccc/Tcc	-0,93	0,02	0	probably_damaging	1	neutral	0,4	neutral	1,21	deleterious	-6,02	deleterious	-7,18	high_impact	3,79	damaging	0,58	damaging	0,1	deleterious	3,99	23,6	0,05	0,35	neutral	0,48	disease	0,83	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,18	high_impact	2,12	0,15	0,8	60,06	10,39	N	0,26	N	0,74	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9112	9112	C	A	MI.1249	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	586	196	L	M	Cta/Ata	-11,44	0	0	probably_damaging	1	neutral	0,22	neutral	4,32	neutral	-2,16	neutral	-1,64	medium_impact	2,07	neutral	0,74	damaging	0,18	deleterious	3,79	23,4	0,26	0,65	NA	NA	neutral	0,37	disease	0,51	neutral	0,25	5	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,02	medium_impact	0,68	0,56	0,9	20,8	18,46	N	0,35	N	0,96	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4139	4139	C	G	MI.12490	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	833	278	P	R	cCc/cGc	7,11	1	0	probably_damaging	1	neutral	0,35	neutral	1,18	deleterious	-6,98	deleterious	-8,08	high_impact	4,76	neutral	0,6	damaging	0,06	deleterious	3,79	23,4	0,03	0,35	disease	0,69	disease	0,91	disease	0,8	disease	0,82	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,12	high_impact	2,97	0,25	0,8	60,06	10,39	P	0,71	P	0,71	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4139	4139	C	T	MI.12491	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	833	278	P	L	cCc/cTc	7,11	1	0	probably_damaging	1	neutral	0,65	neutral	1,19	deleterious	-6,82	deleterious	-8,97	high_impact	4,42	neutral	0,61	damaging	0,05	deleterious	4,56	24,4	0,03	0,35	disease	0,55	disease	0,9	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,43	high_impact	2,67	0,43	0,8	60,06	10,39	P	0,53	P	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4139	4139	C	A	MI.12492	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	833	278	P	H	cCc/cAc	7,11	1	0	probably_damaging	1	neutral	0,54	neutral	1,17	deleterious	-8,08	deleterious	-8,08	high_impact	4,42	damaging	0,58	damaging	0,05	deleterious	4,17	23,8	0,03	0,35	disease	0,81	disease	0,88	disease	0,79	disease	0,83	7	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,31	high_impact	2,67	0,19	0,8	60,06	10,39	P	0,62	P	0,69	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4141	4141	C	G	MI.12493	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	835	279	R	G	Cga/Gga	-4,38	0	0	probably_damaging	0,91	neutral	0,33	neutral	1,63	deleterious	-6,87	deleterious	-6,28	high_impact	4,76	neutral	0,62	damaging	0,08	deleterious	4,36	24,1	0,02	0,35	disease	0,76	disease	0,82	disease	0,76	disease	0,77	5	neutral	0,92	neutral	0,21	deleterious	2	deleterious	0,78	low_impact	-1,69	medium_impact	0,1	high_impact	2,97	0,07	0,8	59,43	10,54	P	0,59	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4141	4141	C	T	MI.12494	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	835	279	R	W	Cga/Tga	-4,38	0	0	probably_damaging	0,99	neutral	0,19	neutral	1,6	deleterious	-9,36	deleterious	-7,18	high_impact	4,76	neutral	0,72	damaging	0,08	deleterious	5,35	25,9	0,03	0,35	disease	0,94	disease	0,91	disease	0,79	disease	0,84	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-2,62	medium_impact	-0,08	high_impact	2,97	0,33	0,8	59,43	10,54	P	0,59	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4142	4142	G	C	MI.12495	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	836	279	R	P	cGa/cCa	5,5	1	0	benign	0,12	neutral	0,2	neutral	1,61	deleterious	-7,19	deleterious	-6,28	high_impact	4,42	neutral	0,66	damaging	0,07	deleterious	4,46	24,2	0,02	0,35	disease	0,81	disease	0,87	disease	0,83	disease	0,82	6	neutral	0,77	deleterious	0,54	neutral	-2	neutral	0,38	medium_impact	0,06	medium_impact	-0,06	high_impact	2,67	0,07	0,8	59,43	10,54	P	0,61	P	1	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4142	4142	G	T	MI.12496	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	836	279	R	L	cGa/cTa	5,5	1	0	probably_damaging	0,91	neutral	0,65	neutral	1,63	deleterious	-6,26	deleterious	-6,28	high_impact	4,42	damaging	0,59	damaging	0,06	deleterious	4,53	24,3	0,02	0,35	disease	0,73	disease	0,93	disease	0,76	disease	0,79	6	neutral	0,89	neutral	0,37	deleterious	2	deleterious	0,8	low_impact	-1,69	medium_impact	0,43	high_impact	2,67	0,02	0,8	59,43	10,54	P	0,62	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4142	4142	G	A	MI.12497	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	836	279	R	Q	cGa/cAa	5,5	1	0	probably_damaging	0,93	neutral	0,29	neutral	1,65	deleterious	-5,34	deleterious	-3,59	high_impact	4,21	damaging	0,6	damaging	0,06	deleterious	4,64	24,5	0,04	0,35	disease	0,56	disease	0,82	disease	0,74	disease	0,75	5	neutral	0,94	neutral	0,18	deleterious	2	deleterious	0,79	low_impact	-1,81	medium_impact	0,06	high_impact	2,49	0,63	0,8	59,43	10,54	P	0,74	P	1	polymorphism	0,96	0,4	.	.	.	.	.	.	.	.	.	G4142A	Developmental delay,seizure,hypotonia	-	+	Reported	1
chrM	4144	4144	T	A	MI.12498	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	838	280	F	I	Ttc/Atc	0,45	0,97	0	benign	0,03	neutral	0,39	neutral	2,74	neutral	-1,09	deleterious	-5,36	medium_impact	2,42	neutral	0,74	neutral	0,61	deleterious	2,65	20,5	0,1	0,4	neutral	0,2	disease	0,78	neutral	0,34	disease	0,5	0	neutral	0,59	deleterious	0,68	neutral	-3	neutral	0,2	medium_impact	0,67	medium_impact	0,17	medium_impact	0,93	0,55	0,8	55,66	10,13	N	0,48	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4144	4144	T	C	MI.12499	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	838	280	F	L	Ttc/Ctc	0,45	0,97	0	benign	0,02	neutral	0,65	neutral	2,78	neutral	0,14	deleterious	-5,35	medium_impact	2,23	neutral	0,66	neutral	0,67	deleterious	2,27	17,99	0,13	0,4	neutral	0,14	disease	0,78	neutral	0,33	neutral	0,5	0	neutral	0,32	deleterious	0,82	neutral	-3	neutral	0,18	medium_impact	0,84	medium_impact	0,43	medium_impact	0,76	0,61	0,8	55,66	10,13	N	0,38	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8584	8584	G	A	MI.125	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	58	20	A	T	Gca/Aca	-5,89	0	0,17	benign	0,02	neutral	0,39	neutral	4,64	neutral	-0,81	neutral	-0,4	neutral_impact	0,06	neutral	0,99	neutral	0,95	deleterious	0,81	9,54	0,45	0,65	neutral	0,44	neutral	0,23	neutral	0,29	neutral	0,43	1	neutral	0,59	deleterious	0,69	neutral	-6	neutral	0,16	medium_impact	0,85	medium_impact	0,18	low_impact	-1,05	0,49	0,9	24,78	23,03	N	0,46	N	0,01	polymorphism	1	0,01	rs3135028	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9113	9113	T	C	MI.1250	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	587	196	L	P	cTa/cCa	-1,49	0	0	probably_damaging	1	deleterious	0,04	neutral	4,3	deleterious	-3,61	deleterious	-5,89	high_impact	3,6	damaging	0,56	damaging	0,16	deleterious	3,95	23,6	0,15	0,65	NA	NA	disease	0,79	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,88	low_impact	-3,6	medium_impact	-0,49	medium_impact	1,99	0,54	0,9	20,8	18,46	N	0,28	N	1	disease_causing	0,87	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4144	4144	T	G	MI.12500	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	838	280	F	V	Ttc/Gtc	0,45	0,97	0	benign	0,19	neutral	0,5	neutral	2,78	neutral	-0,74	deleterious	-6,25	medium_impact	2,4	neutral	0,63	neutral	0,49	deleterious	2,38	18,71	0,08	0,35	neutral	0,18	disease	0,86	disease	0,61	disease	0,71	4	neutral	0,4	deleterious	0,66	neutral	-3	neutral	0,24	medium_impact	-0,16	medium_impact	0,28	medium_impact	0,91	0,43	0,8	55,66	10,13	N	0,43	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4145	4145	T	C	MI.12501	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	839	280	F	S	tTc/tCc	5,73	1	0	possibly_damaging	0,75	neutral	0,4	neutral	2,67	neutral	-2,67	deleterious	-7,16	high_impact	3,58	neutral	0,71	neutral	0,63	deleterious	2,74	21,1	0,04	0,35	neutral	0,34	disease	0,82	disease	0,62	disease	0,69	4	neutral	0,76	neutral	0,33	deleterious	1	deleterious	0,63	low_impact	-1,2	medium_impact	0,18	medium_impact	1,94	0,18	0,8	55,66	10,13	P	0,6	P	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4145	4145	T	G	MI.12502	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	839	280	F	C	tTc/tGc	5,73	1	0	probably_damaging	0,94	neutral	0,18	neutral	2,63	deleterious	-3,76	deleterious	-7,15	high_impact	3,92	neutral	0,7	neutral	0,48	deleterious	4,03	23,6	0,04	0,35	disease	0,54	disease	0,84	disease	0,63	disease	0,71	4	neutral	0,96	neutral	0,12	deleterious	2	deleterious	0,74	low_impact	-1,87	medium_impact	-0,09	high_impact	2,24	0,18	0,8	55,66	10,13	P	0,65	P	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4145	4145	T	A	MI.12503	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	839	280	F	Y	tTc/tAc	5,73	1	0	possibly_damaging	0,75	neutral	1	neutral	2,75	neutral	-0,89	deleterious	-2,68	medium_impact	1,94	neutral	0,7	neutral	0,46	deleterious	2,79	21,3	0,13	0,4	neutral	0,21	disease	0,56	neutral	0,28	neutral	0,41	2	neutral	0,75	deleterious	0,63	NA	0	deleterious	0,47	low_impact	-1,2	high_impact	1,96	medium_impact	0,51	0,66	0,8	55,66	10,13	N	0,53	P	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4146	4146	C	G	MI.12504	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	840	280	F	L	ttC/ttG	7,34	1	0	benign	0,02	neutral	0,65	neutral	2,78	neutral	0,14	deleterious	-5,35	medium_impact	2,23	neutral	0,66	neutral	0,67	deleterious	2,55	19,78	0,13	0,4	neutral	0,14	disease	0,78	neutral	0,33	neutral	0,5	0	neutral	0,32	deleterious	0,82	neutral	-3	neutral	0,18	medium_impact	0,84	medium_impact	0,43	medium_impact	0,76	0,61	0,8	55,66	10,13	N	0,52	P	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4146	4146	C	A	MI.12505	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	840	280	F	L	ttC/ttA	7,34	1	0	benign	0,02	neutral	0,65	neutral	2,78	neutral	0,14	deleterious	-5,35	medium_impact	2,23	neutral	0,66	neutral	0,67	deleterious	2,83	21,5	0,13	0,4	neutral	0,14	disease	0,78	neutral	0,33	neutral	0,5	0	neutral	0,32	deleterious	0,82	neutral	-3	neutral	0,18	medium_impact	0,84	medium_impact	0,43	medium_impact	0,76	0,61	0,8	55,66	10,13	N	0,52	P	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4147	4147	C	T	MI.12506	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	841	281	R	C	Cgc/Tgc	-3,46	0	0	benign	0,01	neutral	0,17	neutral	1,6	deleterious	-9,27	deleterious	-7,16	high_impact	4,75	damaging	0,55	damaging	0,18	deleterious	3,17	22,7	0,06	0,35	disease	0,93	disease	0,83	disease	0,78	disease	0,85	7	neutral	0,83	deleterious	0,58	neutral	-2	neutral	0,33	medium_impact	1,12	medium_impact	-0,11	high_impact	2,96	0,65	0,8	58,49	10,46	P	0,51	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4147	4147	C	A	MI.12507	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	841	281	R	S	Cgc/Agc	-3,46	0	0	possibly_damaging	0,65	neutral	0,43	neutral	1,64	deleterious	-6,12	deleterious	-5,37	high_impact	4,39	damaging	0,55	neutral	0,35	deleterious	2,76	21,2	0,03	0,35	disease	0,65	disease	0,78	disease	0,73	disease	0,74	5	neutral	0,66	neutral	0,39	deleterious	1	deleterious	0,55	low_impact	-1	medium_impact	0,21	high_impact	2,65	0,18	0,8	58,49	10,46	N	0,42	N	0,74	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4147	4147	C	G	MI.12508	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	841	281	R	G	Cgc/Ggc	-3,46	0	0	possibly_damaging	0,78	neutral	0,32	neutral	1,63	deleterious	-7,07	deleterious	-6,27	high_impact	4,39	damaging	0,59	neutral	0,35	deleterious	2,47	19,28	0,03	0,35	disease	0,75	disease	0,75	disease	0,74	disease	0,75	5	neutral	0,81	neutral	0,27	deleterious	1	deleterious	0,58	low_impact	-1,27	medium_impact	0,09	high_impact	2,65	0,17	0,8	58,49	10,46	N	0,42	N	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4148	4148	G	C	MI.12509	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	842	281	R	P	cGc/cCc	4,35	1	0	probably_damaging	0,94	neutral	0,21	neutral	1,61	deleterious	-7,52	deleterious	-6,27	high_impact	4,04	damaging	0,57	damaging	0,26	deleterious	2,78	21,2	0,02	0,35	disease	0,81	disease	0,84	disease	0,84	disease	0,8	6	neutral	0,96	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-1,87	medium_impact	-0,05	high_impact	2,34	0,13	0,8	58,49	10,46	P	0,6	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9113	9113	T	A	MI.1251	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	587	196	L	Q	cTa/cAa	-1,49	0	0	probably_damaging	1	neutral	0,48	neutral	4,31	deleterious	-3,26	deleterious	-5,1	low_impact	1,73	damaging	0,57	damaging	0,15	deleterious	4,07	23,7	0,17	0,65	NA	NA	neutral	0,42	neutral	0,41	neutral	0,18	6	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,27	medium_impact	0,39	0,54	0,9	20,8	18,46	N	0,3	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4148	4148	G	T	MI.12510	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	842	281	R	L	cGc/cTc	4,35	1	0	possibly_damaging	0,52	neutral	0,65	neutral	1,63	deleterious	-6,64	deleterious	-6,26	high_impact	4,39	damaging	0,56	neutral	0,3	deleterious	2,57	19,89	0,03	0,35	disease	0,73	disease	0,9	disease	0,74	disease	0,77	5	neutral	0,43	deleterious	0,57	deleterious	1	deleterious	0,52	medium_impact	-0,78	medium_impact	0,43	high_impact	2,65	0,1	0,8	58,49	10,46	P	0,59	P	1	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4148	4148	G	A	MI.12511	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	842	281	R	H	cGc/cAc	4,35	1	0	probably_damaging	0,96	neutral	0,52	neutral	1,62	deleterious	-6,4	deleterious	-4,48	high_impact	4,75	damaging	0,48	damaging	0,18	deleterious	4,14	23,8	0,06	0,35	disease	0,74	disease	0,79	disease	0,77	disease	0,76	5	neutral	0,95	neutral	0,28	deleterious	2	deleterious	0,82	low_impact	-2,05	medium_impact	0,29	high_impact	2,96	0,75	0,85	58,49	10,46	P	0,74	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4150	4150	T	A	MI.12512	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	844	282	Y	N	Tac/Aac	-8,97	0	0	probably_damaging	1	neutral	0,23	neutral	2,41	deleterious	-4,09	deleterious	-8,06	high_impact	4,64	neutral	0,66	neutral	0,33	deleterious	4,19	23,8	0,05	0,35	neutral	0,49	disease	0,88	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	-0,02	high_impact	2,86	0,15	0,8	59,43	10,34	N	0,54	P	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4150	4150	T	C	MI.12513	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	844	282	Y	H	Tac/Cac	-8,97	0	0	probably_damaging	1	neutral	0,39	neutral	2,41	deleterious	-4,23	deleterious	-4,48	high_impact	4,64	neutral	0,63	damaging	0,26	deleterious	3,75	23,3	0,11	0,4	disease	0,56	disease	0,82	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	0,17	high_impact	2,86	0,23	0,8	59,43	10,34	N	0,55	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4150	4150	T	G	MI.12514	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	844	282	Y	D	Tac/Gac	-8,97	0	0	probably_damaging	1	neutral	0,21	neutral	2,4	deleterious	-4,59	deleterious	-8,96	high_impact	4,1	neutral	0,68	neutral	0,3	deleterious	4,12	23,8	0,03	0,35	disease	0,58	disease	0,89	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	-0,05	high_impact	2,39	0,13	0,8	59,43	10,34	N	0,48	N	1	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4151	4151	A	C	MI.12515	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	845	282	Y	S	tAc/tCc	7,34	1	0	probably_damaging	1	neutral	0,42	neutral	2,43	deleterious	-3,25	deleterious	-8,06	high_impact	4,1	neutral	0,64	neutral	0,39	deleterious	3,85	23,4	0,04	0,35	neutral	0,26	disease	0,84	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,2	high_impact	2,39	0,22	0,8	59,43	10,34	P	0,62	P	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4151	4151	A	T	MI.12516	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	845	282	Y	F	tAc/tTc	7,34	1	0	probably_damaging	1	neutral	0,6	neutral	2,48	neutral	-2,39	deleterious	-3,59	medium_impact	2,71	neutral	0,62	neutral	0,29	deleterious	3,59	23,2	0,2	0,45	neutral	0,3	disease	0,79	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,8	low_impact	-3,57	medium_impact	0,37	medium_impact	1,18	0,43	0,8	59,43	10,34	P	0,54	P	0,8	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4151	4151	A	G	MI.12517	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	845	282	Y	C	tAc/tGc	7,34	1	0	probably_damaging	1	neutral	0,14	neutral	2,4	deleterious	-4,87	deleterious	-8,07	high_impact	4,1	neutral	0,67	damaging	0,22	deleterious	3,68	23,3	0,03	0,35	disease	0,57	disease	0,85	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	-0,17	high_impact	2,39	0,08	0,8	59,43	10,34	P	0,67	P	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4153	4153	G	C	MI.12518	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	847	283	D	H	Gac/Cac	-3	0	0	probably_damaging	1	neutral	0,53	neutral	1,55	deleterious	-6,67	deleterious	-6,28	high_impact	4,74	neutral	0,62	damaging	0,25	deleterious	3,77	23,4	0,05	0,35	disease	0,65	disease	0,85	disease	0,8	disease	0,77	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,3	high_impact	2,95	0,41	0,8	58,81	10,84	P	0,65	P	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4153	4153	G	T	MI.12519	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	847	283	D	Y	Gac/Tac	-3	0	0	probably_damaging	1	neutral	1	neutral	1,54	deleterious	-7,42	deleterious	-8,07	high_impact	4,39	neutral	0,66	damaging	0,28	deleterious	4,04	23,7	0,03	0,35	disease	0,77	disease	0,93	disease	0,76	disease	0,8	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,89	low_impact	-3,57	high_impact	1,96	high_impact	2,65	0,13	0,8	58,81	10,84	N	0,44	N	1	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9113	9113	T	G	MI.1252	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	587	196	L	R	cTa/cGa	-1,49	0	0	probably_damaging	1	neutral	0,07	neutral	4,27	deleterious	-3,78	deleterious	-5,14	high_impact	3,6	damaging	0,52	damaging	0,13	deleterious	4,18	23,8	0,16	0,65	NA	NA	disease	0,84	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,34	medium_impact	1,99	0,48	0,9	20,8	18,46	N	0,3	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4153	4153	G	A	MI.12520	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	847	283	D	N	Gac/Aac	-3	0	0	probably_damaging	1	neutral	0,3	neutral	1,59	deleterious	-5,04	deleterious	-4,48	medium_impact	3,35	neutral	0,64	neutral	0,34	deleterious	4,41	24,1	0,27	0,45	neutral	0,45	disease	0,85	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,83	low_impact	-3,57	medium_impact	0,07	medium_impact	1,74	0,77	0,85	58,81	10,84	N	0,41	N	1	polymorphism	1	0,23	rs28566134	.	.	.	.	.	COSM1155631	.	.	.	.	.	.	.	.
chrM	4154	4154	A	C	MI.12521	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	848	283	D	A	gAc/gCc	9,18	1	0	probably_damaging	1	neutral	0,5	neutral	1,58	deleterious	-5,36	deleterious	-7,18	high_impact	4,74	neutral	0,65	neutral	0,39	deleterious	4,28	24	0,05	0,35	neutral	0,46	disease	0,84	disease	0,74	disease	0,75	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,28	high_impact	2,95	0,23	0,8	58,81	10,84	P	0,7	P	0,94	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4154	4154	A	T	MI.12522	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	848	283	D	V	gAc/gTc	9,18	1	0	probably_damaging	1	neutral	0,5	neutral	1,55	deleterious	-6,62	deleterious	-8,07	high_impact	4,74	damaging	0,6	neutral	0,33	deleterious	4,46	24,2	0,03	0,35	disease	0,65	disease	0,91	disease	0,74	disease	0,78	6	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,86	low_impact	-3,57	medium_impact	0,28	high_impact	2,95	0,09	0,8	58,81	10,84	P	0,69	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4154	4154	A	G	MI.12523	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	848	283	D	G	gAc/gGc	9,18	1	0	probably_damaging	1	neutral	0,33	neutral	1,57	deleterious	-5,53	deleterious	-6,28	high_impact	4,2	neutral	0,65	neutral	0,38	deleterious	4,69	24,6	0,05	0,35	disease	0,57	disease	0,86	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,1	high_impact	2,48	0,33	0,8	58,81	10,84	P	0,66	P	0,99	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4155	4155	C	G	MI.12524	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	849	283	D	E	gaC/gaG	8,49	1	0,01	probably_damaging	1	neutral	0,27	neutral	1,64	deleterious	-4,18	deleterious	-3,59	high_impact	4,39	neutral	0,66	neutral	0,35	deleterious	4,03	23,6	0,12	0,4	neutral	0,29	disease	0,78	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,03	high_impact	2,65	0,43	0,8	58,81	10,84	P	0,66	P	0,95	polymorphism	0,97	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4155	4155	C	A	MI.12525	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	849	283	D	E	gaC/gaA	8,49	1	0,01	probably_damaging	1	neutral	0,27	neutral	1,64	deleterious	-4,18	deleterious	-3,59	high_impact	4,39	neutral	0,66	neutral	0,35	deleterious	4,34	24	0,12	0,4	neutral	0,29	disease	0,78	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,03	high_impact	2,65	0,43	0,8	58,81	10,84	P	0,66	P	0,95	polymorphism	0,97	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4156	4156	C	A	MI.12526	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	850	284	Q	K	Caa/Aaa	-3,92	0	0	probably_damaging	1	neutral	0,35	neutral	2,64	neutral	-2,45	deleterious	-3,53	medium_impact	2,23	neutral	0,71	damaging	0,12	deleterious	4,15	23,8	0,15	0,4	neutral	0,22	disease	0,63	neutral	0,39	neutral	0,41	2	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,12	medium_impact	0,76	0,31	0,8	59,12	10,3	N	0,27	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4156	4156	C	G	MI.12527	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	850	284	Q	E	Caa/Gaa	-3,92	0	0	probably_damaging	1	neutral	0,32	neutral	2,54	neutral	-2,77	deleterious	-2,64	high_impact	3,54	neutral	0,74	damaging	0,15	deleterious	3,19	22,7	0,16	0,45	neutral	0,28	disease	0,81	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-3,57	medium_impact	0,09	medium_impact	1,9	0,29	0,8	59,12	10,3	N	0,32	N	0,93	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4157	4157	A	T	MI.12528	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	851	284	Q	L	cAa/cTa	4,4	1	0	probably_damaging	1	neutral	0,67	neutral	2,53	deleterious	-4,2	deleterious	-6,2	medium_impact	2,55	neutral	0,7	damaging	0,1	deleterious	3,95	23,6	0,05	0,35	neutral	0,33	disease	0,91	disease	0,59	disease	0,69	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,82	low_impact	-3,57	medium_impact	0,45	medium_impact	1,04	0,07	0,8	59,12	10,3	N	0,39	N	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4157	4157	A	C	MI.12529	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	851	284	Q	P	cAa/cCa	4,4	1	0	probably_damaging	1	neutral	0,24	neutral	2,46	deleterious	-5,01	deleterious	-5,31	high_impact	4,44	neutral	0,72	damaging	0,13	deleterious	3,46	23	0,02	0,35	disease	0,58	disease	0,92	disease	0,73	disease	0,8	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	-0,01	high_impact	2,69	0,17	0,8	59,12	10,3	P	0,65	P	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9115	9115	A	C	MI.1253	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	589	197	I	L	Att/Ctt	-8,2	0	0,01	benign	0,02	neutral	0,74	neutral	4,53	neutral	-0,18	neutral	-0,57	neutral_impact	-0,13	neutral	0,9	neutral	0,92	neutral	-0,48	0,25	0,17	0,65	NA	NA	neutral	0,18	neutral	0,22	neutral	0,22	6	neutral	0,22	deleterious	0,86	neutral	-6	neutral	0,13	medium_impact	0,85	medium_impact	0,55	low_impact	-1,21	0,28	0,9	24,78	14,04	N	0,37	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4157	4157	A	G	MI.12530	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	851	284	Q	R	cAa/cGa	4,4	1	0	probably_damaging	1	neutral	0,4	neutral	2,55	deleterious	-3	deleterious	-3,51	medium_impact	3,46	neutral	0,77	damaging	0,15	deleterious	3,64	23,2	0,1	0,4	neutral	0,27	disease	0,9	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,81	low_impact	-3,57	medium_impact	0,18	medium_impact	1,83	0,21	0,8	59,12	10,3	N	0,51	P	0,95	polymorphism	0,99	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4158	4158	A	T	MI.12531	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	852	284	Q	H	caA/caT	8,55	1	0	probably_damaging	1	neutral	0,52	neutral	2,47	deleterious	-4,26	deleterious	-4,33	medium_impact	3,24	neutral	0,72	damaging	0,13	deleterious	3,7	23,3	0,13	0,4	disease	0,53	disease	0,83	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,83	low_impact	-3,57	medium_impact	0,29	medium_impact	1,64	0,43	0,8	59,12	10,3	P	0,55	P	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4158	4158	A	C	MI.12532	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	852	284	Q	H	caA/caC	8,55	1	0	probably_damaging	1	neutral	0,52	neutral	2,47	deleterious	-4,26	deleterious	-4,33	medium_impact	3,24	neutral	0,72	damaging	0,13	deleterious	3,56	23,1	0,13	0,4	disease	0,53	disease	0,83	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,83	low_impact	-3,57	medium_impact	0,29	medium_impact	1,64	0,43	0,8	59,12	10,3	N	0,55	P	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4159	4159	C	A	MI.12533	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	853	285	L	I	Ctc/Atc	-0,2	0,5	0	probably_damaging	1	neutral	0,38	neutral	2,1	neutral	-2,86	neutral	-1,79	medium_impact	3,11	damaging	0,56	damaging	0,08	deleterious	4,38	24,1	0,18	0,45	neutral	0,24	disease	0,71	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	0,16	medium_impact	1,53	0,51	0,8	60,06	10,34	N	0,3	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4159	4159	C	T	MI.12534	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	853	285	L	F	Ctc/Ttc	-0,2	0,5	0	probably_damaging	1	neutral	0,8	neutral	2,04	deleterious	-3,65	deleterious	-3,58	medium_impact	2,66	damaging	0,48	damaging	0,06	deleterious	4,08	23,7	0,08	0,35	neutral	0,42	disease	0,75	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,8	low_impact	-3,57	medium_impact	0,61	medium_impact	1,14	0,53	0,8	60,06	10,34	N	0,34	N	0,95	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4159	4159	C	G	MI.12535	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	853	285	L	V	Ctc/Gtc	-0,2	0,5	0	probably_damaging	1	neutral	0,47	neutral	2,1	neutral	-2,81	deleterious	-2,69	medium_impact	3,16	damaging	0,51	damaging	0,06	deleterious	3,54	23,1	0,14	0,4	neutral	0,28	disease	0,67	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	0,25	medium_impact	1,57	0,48	0,8	60,06	10,34	N	0,33	N	0,84	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4160	4160	T	C	MI.12536	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	854	285	L	P	cTc/cCc	1,64	0,94	0	probably_damaging	1	neutral	0,26	neutral	1,96	deleterious	-6,68	deleterious	-6,27	high_impact	4,66	damaging	0,27	damaging	0,06	deleterious	4,12	23,8	0,01	0,35	disease	0,72	disease	0,82	disease	0,8	disease	0,78	6	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	0,02	high_impact	2,88	0,31	0,8	60,06	10,34	P	0,89	P	1	disease_causing_automatic	0	0,36	rs199476119	Pathogenic	Leber's_optic_atrophy	RCV000010372.2	MedGen:OMIM:SNOMED_CT	.	.	.	.	T4160C	LHON	+	-	Reported	10
chrM	4160	4160	T	A	MI.12537	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	854	285	L	H	cTc/cAc	1,64	0,94	0	probably_damaging	1	neutral	0,49	neutral	1,95	deleterious	-6,84	deleterious	-6,27	high_impact	4,66	damaging	0,47	damaging	0,05	deleterious	4,42	24,2	0,03	0,35	disease	0,71	disease	0,84	disease	0,79	disease	0,78	6	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,27	high_impact	2,88	0,29	0,8	60,06	10,34	P	0,6	P	0,97	polymorphism	1	0,36	.	.	.	.	.	MNGIE fibroblasts	.	.	.	.	.	.	.	.	.
chrM	4160	4160	T	G	MI.12538	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	854	285	L	R	cTc/cGc	1,64	0,94	0	probably_damaging	1	neutral	0,49	neutral	1,96	deleterious	-6,1	deleterious	-5,38	high_impact	4,66	damaging	0,36	damaging	0,05	deleterious	4,38	24,1	0,01	0,35	neutral	0,43	disease	0,9	disease	0,8	disease	0,8	6	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,27	high_impact	2,88	0,16	0,8	60,06	10,34	P	0,68	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4162	4162	A	T	MI.12539	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	856	286	M	L	Ata/Tta	-7,8	0	0	probably_damaging	0,98	neutral	0,65	neutral	2,79	neutral	-0,05	deleterious	-2,68	medium_impact	3,08	neutral	0,77	damaging	0,14	deleterious	3,38	23	0,16	0,45	neutral	0,17	disease	0,83	disease	0,59	disease	0,69	4	deleterious	0,98	neutral	0,34	deleterious	1	deleterious	0,75	low_impact	-2,34	medium_impact	0,43	medium_impact	1,5	0,31	0,8	59,12	10,29	N	0,24	N	0,95	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9115	9115	A	G	MI.1254	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	589	197	I	V	Att/Gtt	-8,2	0	0,01	benign	0,01	neutral	1	neutral	4,48	neutral	-0,35	neutral	-0,23	neutral_impact	-0,16	neutral	0,87	neutral	0,96	neutral	-1,06	0,01	0,48	0,65	NA	NA	neutral	0,16	neutral	0,31	neutral	0,21	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,14	high_impact	1,98	low_impact	-1,24	0,28	0,9	24,78	14,04	N	0,28	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4162	4162	A	G	MI.12540	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	856	286	M	V	Ata/Gta	-7,8	0	0	probably_damaging	0,99	neutral	0,5	neutral	2,46	neutral	-2,05	deleterious	-3,58	medium_impact	2,97	damaging	0,54	damaging	0,09	deleterious	2,81	21,4	0,14	0,4	neutral	0,24	disease	0,83	disease	0,68	disease	0,7	4	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,77	low_impact	-2,62	medium_impact	0,28	medium_impact	1,41	0,33	0,8	59,12	10,29	N	0,26	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4162	4162	A	C	MI.12541	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	856	286	M	L	Ata/Cta	-7,8	0	0	probably_damaging	0,98	neutral	0,65	neutral	2,79	neutral	-0,05	deleterious	-2,68	medium_impact	3,08	neutral	0,77	damaging	0,14	deleterious	3,28	22,8	0,16	0,45	neutral	0,17	disease	0,83	disease	0,59	disease	0,69	4	deleterious	0,98	neutral	0,34	deleterious	1	deleterious	0,75	low_impact	-2,34	medium_impact	0,43	medium_impact	1,5	0,31	0,8	59,12	10,29	N	0,23	N	0,95	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4163	4163	T	C	MI.12542	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	857	286	M	T	aTa/aCa	8,55	1	0	probably_damaging	1	neutral	0,39	neutral	2,37	deleterious	-3,81	deleterious	-5,37	high_impact	3,62	damaging	0,57	damaging	0,11	deleterious	3,11	22,5	0,04	0,35	neutral	0,27	disease	0,88	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,17	medium_impact	1,97	0,15	0,8	59,12	10,29	N	0,51	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	T4163C	LHON (putative)	+	-	Reported	1
chrM	4163	4163	T	A	MI.12543	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	857	286	M	K	aTa/aAa	8,55	1	0	probably_damaging	1	neutral	0,29	neutral	2,36	deleterious	-4,46	deleterious	-5,38	high_impact	4,33	neutral	0,63	damaging	0,09	deleterious	4,1	23,7	0,02	0,35	neutral	0,24	disease	0,9	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,06	high_impact	2,59	0,17	0,8	59,12	10,29	P	0,63	P	1	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4164	4164	A	T	MI.12544	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	858	286	M	I	atA/atT	4,63	1	0,09	probably_damaging	0,99	neutral	0,39	neutral	2,48	neutral	-1,85	deleterious	-3,57	medium_impact	3	neutral	0,61	damaging	0,09	deleterious	3,6	23,2	0,11	0,4	neutral	0,3	disease	0,84	disease	0,62	disease	0,7	4	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-2,62	medium_impact	0,17	medium_impact	1,43	0,26	0,8	59,12	10,29	N	0,5	N	0,95	disease_causing	1	0,15	rs386420034	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4164	4164	A	C	MI.12545	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	858	286	M	I	atA/atC	4,63	1	0,09	probably_damaging	0,99	neutral	0,39	neutral	2,48	neutral	-1,85	deleterious	-3,57	medium_impact	3	neutral	0,61	damaging	0,09	deleterious	3,56	23,1	0,11	0,4	neutral	0,3	disease	0,84	disease	0,62	disease	0,7	4	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-2,62	medium_impact	0,17	medium_impact	1,43	0,26	0,8	59,12	10,29	N	0,49	N	0,95	disease_causing	1	0,15	rs386420034	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4165	4165	C	T	MI.12546	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	859	287	H	Y	Cac/Tac	-0,43	0,07	0	benign	0,02	neutral	1	neutral	2,81	neutral	-0,53	deleterious	-5,09	low_impact	1,35	neutral	0,74	neutral	0,73	deleterious	1,84	15,23	0,19	0,45	neutral	0,27	disease	0,52	neutral	0,16	neutral	0,41	2	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,21	medium_impact	0,84	high_impact	1,96	medium_impact	-0,01	0,27	0,8	18,87	12,35	N	0,36	N	0,55	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4165	4165	C	A	MI.12547	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	859	287	H	N	Cac/Aac	-0,43	0,07	0	possibly_damaging	0,44	neutral	0,17	neutral	2,85	neutral	1,37	deleterious	-6,15	low_impact	1,76	neutral	0,69	neutral	0,34	deleterious	2,18	17,38	0,24	0,45	neutral	0,15	disease	0,81	neutral	0,26	neutral	0,49	0	neutral	0,8	neutral	0,37	neutral	-3	neutral	0,41	medium_impact	-0,65	medium_impact	-0,11	medium_impact	0,35	0,35	0,8	18,87	12,35	N	0,39	N	0,89	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4165	4165	C	G	MI.12548	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	859	287	H	D	Cac/Gac	-0,43	0,07	0	possibly_damaging	0,57	neutral	0,2	neutral	2,82	neutral	1,07	deleterious	-7,9	medium_impact	2,21	neutral	0,72	neutral	0,3	deleterious	2,17	17,29	0,06	0,35	neutral	0,17	disease	0,83	disease	0,51	disease	0,7	4	neutral	0,8	neutral	0,32	NA	0	neutral	0,43	medium_impact	-0,87	medium_impact	-0,06	medium_impact	0,74	0,33	0,8	18,87	12,35	N	0,38	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4166	4166	A	T	MI.12549	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	860	287	H	L	cAc/cTc	2,79	0,98	0	possibly_damaging	0,44	neutral	0,74	neutral	2,8	neutral	-0,59	deleterious	-9,58	medium_impact	2,6	neutral	0,68	neutral	0,36	deleterious	1,95	15,92	0,06	0,35	neutral	0,29	disease	0,88	neutral	0,45	disease	0,73	5	neutral	0,33	deleterious	0,65	NA	0	neutral	0,39	medium_impact	-0,65	medium_impact	0,53	medium_impact	1,08	0,21	0,8	18,87	12,35	N	0,45	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9115	9115	A	T	MI.1255	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	589	197	I	F	Att/Ttt	-8,2	0	0,01	benign	0,16	neutral	0,9	neutral	4,31	neutral	-1,64	neutral	-0,89	neutral_impact	-0,2	neutral	0,88	neutral	0,95	neutral	-0,62	0,11	0,3	0,65	NA	NA	neutral	0,25	neutral	0,25	neutral	0,17	7	neutral	0,07	deleterious	0,87	neutral	-6	neutral	0,31	medium_impact	-0,07	medium_impact	0,83	low_impact	-1,27	0,37	0,9	24,78	14,04	N	0,3	N	0,03	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4166	4166	A	G	MI.12550	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	860	287	H	R	cAc/cGc	2,79	0,98	0	possibly_damaging	0,57	neutral	0,48	neutral	2,86	neutral	1,93	deleterious	-7,01	low_impact	1,86	neutral	0,67	damaging	0,28	neutral	1,14	11,41	0,12	0,4	neutral	0,14	disease	0,82	neutral	0,22	neutral	0,48	0	neutral	0,57	neutral	0,46	neutral	-3	neutral	0,39	medium_impact	-0,87	medium_impact	0,26	medium_impact	0,44	0,3	0,8	18,87	12,35	N	0,42	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4166	4166	A	C	MI.12551	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	860	287	H	P	cAc/cCc	2,79	0,98	0	possibly_damaging	0,89	neutral	0,13	neutral	2,77	neutral	-1,16	deleterious	-8,76	medium_impact	3,45	neutral	0,69	damaging	0,27	neutral	1,6	13,84	0,05	0,35	neutral	0,37	disease	0,91	disease	0,62	disease	0,73	5	neutral	0,95	neutral	0,12	NA	0	deleterious	0,72	low_impact	-1,6	medium_impact	-0,19	medium_impact	1,82	0,15	0,8	18,87	12,35	P	0,56	P	0,97	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4167	4167	C	G	MI.12552	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	861	287	H	Q	caC/caG	6,71	0,99	0	benign	0,06	neutral	0,24	neutral	2,83	neutral	0,83	deleterious	-6,98	medium_impact	2,9	neutral	0,72	neutral	0,42	deleterious	1,92	15,69	0,17	0,45	neutral	0,17	disease	0,75	neutral	0,25	disease	0,53	1	neutral	0,74	deleterious	0,59	neutral	-3	neutral	0,21	medium_impact	0,37	medium_impact	-0,01	medium_impact	1,34	0,34	0,8	18,87	12,35	P	0,58	P	0,84	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4167	4167	C	A	MI.12553	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	861	287	H	Q	caC/caA	6,71	0,99	0	benign	0,06	neutral	0,24	neutral	2,83	neutral	0,83	deleterious	-6,98	medium_impact	2,9	neutral	0,72	neutral	0,42	deleterious	2,25	17,85	0,17	0,45	neutral	0,17	disease	0,75	neutral	0,25	disease	0,53	1	neutral	0,74	deleterious	0,59	neutral	-3	neutral	0,21	medium_impact	0,37	medium_impact	-0,01	medium_impact	1,34	0,34	0,8	18,87	12,35	P	0,58	P	0,84	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4168	4168	C	G	MI.12554	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	862	288	L	V	Ctc/Gtc	-2,04	0	0	probably_damaging	1	neutral	0,45	neutral	2,06	deleterious	-3,12	deleterious	-2,64	medium_impact	3,44	neutral	0,68	damaging	0,1	deleterious	3,55	23,1	0,2	0,45	neutral	0,33	disease	0,64	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	0,23	medium_impact	1,82	0,59	0,8	59,43	10,44	N	0,27	N	0,84	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4168	4168	C	A	MI.12555	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	862	288	L	I	Ctc/Atc	-2,04	0	0	probably_damaging	1	neutral	0,39	neutral	2,13	neutral	-2,49	neutral	-1,76	medium_impact	2,97	neutral	0,79	damaging	0,14	deleterious	4,38	24,1	0,24	0,45	neutral	0,31	disease	0,69	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,17	medium_impact	1,41	0,5	0,8	59,43	10,44	N	0,23	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4168	4168	C	T	MI.12556	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	862	288	L	F	Ctc/Ttc	-2,04	0	0	probably_damaging	1	neutral	0,65	neutral	2,05	deleterious	-3,26	deleterious	-3,52	medium_impact	2,29	neutral	0,69	damaging	0,08	deleterious	4,08	23,7	0,15	0,4	neutral	0,38	disease	0,71	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,77	low_impact	-3,57	medium_impact	0,43	medium_impact	0,81	0,57	0,8	59,43	10,44	N	0,19	N	0,95	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4169	4169	T	A	MI.12557	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	863	288	L	H	cTc/cAc	-0,2	0	0	probably_damaging	1	neutral	0,46	neutral	1,93	deleterious	-6,86	deleterious	-6,16	high_impact	4,54	neutral	0,72	damaging	0,09	deleterious	4,3	24	0,02	0,35	disease	0,84	disease	0,84	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	0,24	high_impact	2,78	0,28	0,8	59,43	10,44	N	0,45	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4169	4169	T	C	MI.12558	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	863	288	L	P	cTc/cCc	-0,2	0	0	probably_damaging	1	neutral	0,2	neutral	1,94	deleterious	-6,8	deleterious	-6,18	high_impact	4,2	neutral	0,78	damaging	0,08	deleterious	4,07	23,7	0,01	0,35	disease	0,83	disease	0,82	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,06	high_impact	2,48	0,38	0,8	59,43	10,44	N	0,35	N	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4169	4169	T	G	MI.12559	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	863	288	L	R	cTc/cGc	-0,2	0	0	probably_damaging	1	neutral	0,37	neutral	1,94	deleterious	-6,24	deleterious	-5,28	high_impact	4,54	neutral	0,76	damaging	0,07	deleterious	4,36	24,1	0,01	0,35	disease	0,78	disease	0,89	disease	0,76	disease	0,82	6	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,88	low_impact	-3,57	medium_impact	0,15	high_impact	2,78	0,15	0,8	59,43	10,44	N	0,49	N	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9116	9116	T	G	MI.1256	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	590	197	I	S	aTt/aGt	-4,73	0	0	benign	0,02	neutral	0,07	neutral	4,27	neutral	-2,95	deleterious	-2,92	low_impact	1,6	neutral	0,83	neutral	0,46	deleterious	2,5	19,47	0,28	0,65	NA	NA	disease	0,58	neutral	0,47	neutral	0,46	1	neutral	0,93	deleterious	0,53	neutral	-6	neutral	0,19	medium_impact	0,85	medium_impact	-0,34	medium_impact	0,27	0,34	0,9	24,78	14,04	N	0,38	N	0,25	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4171	4171	C	G	MI.12560	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	865	289	L	V	Cta/Gta	-13,09	0	0,01	probably_damaging	1	neutral	0,49	neutral	2,79	neutral	-0,82	neutral	-0,28	neutral_impact	0,46	neutral	0,88	neutral	0,71	neutral	1,77	14,81	0,22	0,45	neutral	0,17	neutral	0,17	neutral	0,16	neutral	0,29	4	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,65	low_impact	-3,57	medium_impact	0,27	medium_impact	-0,79	0,52	0,8	59,43	10,63	N	0,47	N	0,84	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4171	4171	C	A	MI.12561	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	865	289	L	M	Cta/Ata	-13,09	0	0,01	probably_damaging	1	neutral	0,24	neutral	2,7	neutral	-1,96	neutral	-0,98	low_impact	1,76	neutral	0,75	neutral	0,56	deleterious	3,81	23,4	0,22	0,45	neutral	0,32	neutral	0,32	neutral	0,18	neutral	0,48	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,68	low_impact	-3,57	medium_impact	-0,01	medium_impact	0,35	0,44	0,8	59,43	10,63	P	0,6	P	0,89	disease_causing_automatic	0	0,03	rs28616230	Pathogenic	Leber's_optic_atrophy	RCV000010384.4	MedGen:OMIM:SNOMED_CT	.	.	.	.	C4171A	LHON	+	+	Cfrm	7
chrM	4172	4172	T	A	MI.12562	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	866	289	L	Q	cTa/cAa	-0,66	0	0	probably_damaging	1	neutral	0,33	neutral	2,71	neutral	-2,72	deleterious	-4,14	medium_impact	3,21	neutral	0,74	neutral	0,33	deleterious	4,23	23,9	0,04	0,35	neutral	0,38	disease	0,68	neutral	0,37	neutral	0,49	0	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,74	low_impact	-3,57	medium_impact	0,1	medium_impact	1,62	0,24	0,8	59,43	10,63	N	0,39	N	0,99	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4172	4172	T	G	MI.12563	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	866	289	L	R	cTa/cGa	-0,66	0	0	probably_damaging	1	neutral	0,35	neutral	2,71	neutral	-2,67	deleterious	-4,38	medium_impact	3,21	neutral	0,71	damaging	0,28	deleterious	4,35	24,1	0,02	0,35	neutral	0,39	disease	0,85	disease	0,51	disease	0,72	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-3,57	medium_impact	0,12	medium_impact	1,62	0,17	0,8	59,43	10,63	N	0,36	N	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4172	4172	T	C	MI.12564	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	866	289	L	P	cTa/cCa	-0,66	0	0	probably_damaging	1	neutral	0,23	neutral	2,68	deleterious	-3,48	deleterious	-4,57	medium_impact	2,51	neutral	0,65	damaging	0,26	deleterious	4,07	23,7	0,02	0,35	disease	0,51	disease	0,85	disease	0,53	disease	0,74	5	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,83	low_impact	-3,57	medium_impact	-0,02	medium_impact	1	0,19	0,8	59,43	10,63	N	0,3	N	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4174	4174	T	G	MI.12565	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	868	290	W	G	Tga/Gga	-0,66	0,06	0	probably_damaging	1	neutral	0,35	neutral	1,99	deleterious	-5,36	deleterious	-11,62	high_impact	4,39	neutral	0,69	damaging	0,12	deleterious	4,04	23,7	0,02	0,35	disease	0,72	disease	0,84	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	0,12	high_impact	2,65	0,04	0,8	60,06	10,24	N	0,48	N	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4174	4174	T	C	MI.12566	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	868	290	W	R	Tga/Cga	-0,66	0,06	0	probably_damaging	1	neutral	0,37	neutral	2,05	deleterious	-3,78	deleterious	-12,52	high_impact	4,19	neutral	0,7	damaging	0,08	deleterious	3,72	23,3	0,02	0,35	neutral	0,5	disease	0,91	disease	0,79	disease	0,79	6	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,15	high_impact	2,47	0,03	0,8	60,06	10,24	N	0,51	P	0,98	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4175	4175	G	T	MI.12567	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	869	290	W	L	tGa/tTa	5,55	1	0	probably_damaging	1	neutral	0,89	neutral	2,04	deleterious	-3,92	deleterious	-11,62	high_impact	4,39	neutral	0,74	damaging	0,1	deleterious	4,38	24,1	0,03	0,35	neutral	0,44	disease	0,86	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,8	low_impact	-3,57	medium_impact	0,78	high_impact	2,65	0,03	0,8	60,06	10,24	P	0,54	P	1	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4175	4175	G	C	MI.12568	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	869	290	W	S	tGa/tCa	5,55	1	0	probably_damaging	1	neutral	0,42	neutral	2,01	deleterious	-4,72	deleterious	-12,52	high_impact	4,19	neutral	0,69	damaging	0,13	deleterious	4,17	23,8	0,02	0,35	disease	0,6	disease	0,88	disease	0,74	disease	0,77	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,84	low_impact	-3,57	medium_impact	0,2	high_impact	2,47	0,03	0,8	60,06	10,24	P	0,58	P	0,99	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4176	4176	A	T	MI.12569	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	870	290	W	C	tgA/tgT	9,01	1	0	probably_damaging	1	neutral	0,18	neutral	1,98	deleterious	-6,71	deleterious	-11,62	high_impact	4,39	neutral	0,69	damaging	0,08	deleterious	4,28	24	0,02	0,35	disease	0,82	disease	0,88	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,09	high_impact	2,65	0,06	0,8	60,06	10,24	P	0,62	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9116	9116	T	C	MI.1257	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	590	197	I	T	aTt/aCt	-4,73	0	0	benign	0	neutral	0,2	neutral	4,28	neutral	-2,08	neutral	-2,02	low_impact	1,36	neutral	0,98	neutral	0,95	deleterious	0,21	4,78	0,38	0,65	NA	NA	neutral	0,26	neutral	0,38	neutral	0,16	7	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,14	high_impact	2,09	medium_impact	-0,05	medium_impact	0,07	0,42	0,9	24,78	14,04	N	0,42	N	0,04	polymorphism	1	0,04	rs376203575	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4176	4176	A	C	MI.12570	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	870	290	W	C	tgA/tgC	9,01	1	0	probably_damaging	1	neutral	0,18	neutral	1,98	deleterious	-6,71	deleterious	-11,62	high_impact	4,39	neutral	0,69	damaging	0,08	deleterious	4,15	23,8	0,02	0,35	disease	0,82	disease	0,88	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,57	medium_impact	-0,09	high_impact	2,65	0,06	0,8	60,06	10,24	P	0,62	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4177	4177	A	G	MI.12571	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	871	291	K	E	Aaa/Gaa	4,63	1	0	probably_damaging	1	neutral	0,14	neutral	2,35	neutral	-2,87	deleterious	-3,56	high_impact	3,51	neutral	0,68	damaging	0,06	deleterious	4,18	23,8	0,11	0,4	neutral	0,29	disease	0,82	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	-0,17	medium_impact	1,88	0,4	0,8	59,12	10,4	P	0,54	P	0,92	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4177	4177	A	C	MI.12572	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	871	291	K	Q	Aaa/Caa	4,63	1	0	probably_damaging	1	neutral	0,28	neutral	2,33	deleterious	-3,18	deleterious	-3,56	high_impact	3,71	neutral	0,61	damaging	0,07	deleterious	3,65	23,2	0,18	0,45	neutral	0,35	disease	0,79	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	0,05	high_impact	2,05	0,43	0,8	59,12	10,4	P	0,56	P	0,92	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4178	4178	A	C	MI.12573	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	872	291	K	T	aAa/aCa	8,55	1	0	probably_damaging	1	neutral	0,26	neutral	2,32	deleterious	-3,36	deleterious	-5,33	medium_impact	3,13	damaging	0,59	damaging	0,07	deleterious	3,55	23,1	0,07	0,35	neutral	0,3	disease	0,78	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	0,02	medium_impact	1,55	0,28	0,8	59,12	10,4	P	0,53	P	0,82	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4178	4178	A	T	MI.12574	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	872	291	K	M	aAa/aTa	8,55	1	0	probably_damaging	1	neutral	0,41	neutral	2,29	deleterious	-4,65	deleterious	-5,34	medium_impact	3,46	neutral	0,65	damaging	0,05	deleterious	3,83	23,4	0,07	0,35	disease	0,6	disease	0,81	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-3,57	medium_impact	0,19	medium_impact	1,83	0,15	0,8	59,12	10,4	P	0,55	P	0,5	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4179	4179	A	T	MI.12575	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	873	291	K	N	aaA/aaT	6,71	1	0	probably_damaging	1	neutral	0,15	neutral	2,32	deleterious	-3,54	deleterious	-4,45	high_impact	3,71	neutral	0,63	damaging	0,06	deleterious	3,87	23,5	0,19	0,45	neutral	0,39	disease	0,8	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	-0,15	high_impact	2,05	0,37	0,8	59,12	10,4	P	0,61	P	0,84	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4179	4179	A	C	MI.12576	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	873	291	K	N	aaA/aaC	6,71	1	0	probably_damaging	1	neutral	0,15	neutral	2,32	deleterious	-3,54	deleterious	-4,45	high_impact	3,71	neutral	0,63	damaging	0,06	deleterious	3,79	23,4	0,19	0,45	neutral	0,39	disease	0,8	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,78	low_impact	-3,57	medium_impact	-0,15	high_impact	2,05	0,37	0,8	59,12	10,4	P	0,6	P	0,84	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4180	4180	A	C	MI.12577	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	874	292	N	H	Aac/Cac	4,63	1	0	probably_damaging	0,96	neutral	0,56	neutral	2,74	neutral	-1,11	deleterious	-3,87	medium_impact	3,15	neutral	0,72	neutral	0,39	deleterious	3,1	22,5	0,28	0,45	neutral	0,36	disease	0,67	neutral	0,31	neutral	0,49	0	neutral	0,96	neutral	0,3	deleterious	1	deleterious	0,68	low_impact	-2,05	medium_impact	0,33	medium_impact	1,56	0,2	0,8	55,97	9,7	N	0,47	N	0,79	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4180	4180	A	T	MI.12578	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	874	292	N	Y	Aac/Tac	4,63	1	0	probably_damaging	0,96	neutral	1	neutral	2,75	neutral	1,2	deleterious	-6,25	medium_impact	2	neutral	0,72	neutral	0,4	deleterious	3,64	23,2	0,12	0,4	neutral	0,29	disease	0,71	neutral	0,41	neutral	0,5	0	neutral	0,96	deleterious	0,52	deleterious	1	deleterious	0,7	low_impact	-2,05	high_impact	1,96	medium_impact	0,56	0,13	0,8	55,97	9,7	N	0,38	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4180	4180	A	G	MI.12579	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	874	292	N	D	Aac/Gac	4,63	1	0	possibly_damaging	0,64	neutral	0,2	neutral	2,76	neutral	-1,28	deleterious	-3,82	medium_impact	2,69	neutral	0,74	neutral	0,48	deleterious	3,83	23,4	0,38	0,5	neutral	0,26	disease	0,61	neutral	0,38	neutral	0,49	0	neutral	0,82	neutral	0,28	NA	0	deleterious	0,51	medium_impact	-0,99	medium_impact	-0,06	medium_impact	1,16	0,29	0,8	55,97	9,7	P	0,67	P	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9116	9116	T	A	MI.1258	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	590	197	I	N	aTt/aAt	-4,73	0	0	benign	0,04	neutral	0,1	neutral	4,26	deleterious	-4,32	deleterious	-3,94	medium_impact	2,38	neutral	0,84	neutral	0,45	deleterious	2,78	21,3	0,24	0,65	NA	NA	disease	0,6	disease	0,56	disease	0,68	4	neutral	0,89	deleterious	0,53	neutral	-3	neutral	0,28	medium_impact	0,55	medium_impact	-0,25	medium_impact	0,94	0,4	0,9	24,78	14,04	N	0,38	N	0,49	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4181	4181	A	T	MI.12580	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	875	292	N	I	aAc/aTc	6,71	1	0	probably_damaging	0,93	neutral	0,41	neutral	2,81	neutral	2,24	deleterious	-7,14	low_impact	1,54	neutral	0,74	neutral	0,47	deleterious	3,87	23,5	0,13	0,4	neutral	0,19	disease	0,75	neutral	0,24	neutral	0,49	0	neutral	0,93	neutral	0,24	neutral	-2	deleterious	0,66	low_impact	-1,81	medium_impact	0,19	medium_impact	0,16	0,11	0,8	55,97	9,7	N	0,51	P	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4181	4181	A	G	MI.12581	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	875	292	N	S	aAc/aGc	6,71	1	0	benign	0,13	neutral	0,42	neutral	2,82	neutral	1,1	deleterious	-3,61	low_impact	1,12	neutral	0,79	neutral	0,9	deleterious	1,95	15,89	0,37	0,5	neutral	0,14	neutral	0,19	neutral	0,19	neutral	0,34	3	neutral	0,51	deleterious	0,65	neutral	-6	neutral	0,15	medium_impact	0,02	medium_impact	0,2	medium_impact	-0,21	0,24	0,8	55,97	9,7	P	0,56	P	0,46	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4181	4181	A	C	MI.12582	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	875	292	N	T	aAc/aCc	6,71	1	0	possibly_damaging	0,64	neutral	0,39	neutral	2,8	neutral	1,01	deleterious	-4,52	low_impact	1,38	neutral	0,72	neutral	0,55	deleterious	3,38	22,9	0,24	0,45	neutral	0,2	neutral	0,5	neutral	0,23	neutral	0,44	1	neutral	0,68	neutral	0,38	neutral	-3	deleterious	0,46	medium_impact	-0,99	medium_impact	0,17	medium_impact	0,02	0,32	0,8	55,97	9,7	P	0,59	P	0,76	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4182	4182	C	G	MI.12583	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	876	292	N	K	aaC/aaG	1,41	0,59	0	benign	0,05	neutral	0,31	neutral	2,83	neutral	0,67	deleterious	-4,48	low_impact	1,76	neutral	0,72	neutral	0,53	deleterious	4,13	23,8	0,28	0,45	neutral	0,15	disease	0,68	neutral	0,28	neutral	0,48	0	neutral	0,66	deleterious	0,63	neutral	-6	neutral	0,16	medium_impact	0,45	medium_impact	0,08	medium_impact	0,35	0,24	0,8	55,97	9,7	N	0,36	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4182	4182	C	A	MI.12584	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	876	292	N	K	aaC/aaA	1,41	0,59	0	benign	0,05	neutral	0,31	neutral	2,83	neutral	0,67	deleterious	-4,48	low_impact	1,76	neutral	0,72	neutral	0,53	deleterious	4,54	24,3	0,28	0,45	neutral	0,15	disease	0,68	neutral	0,28	neutral	0,48	0	neutral	0,66	deleterious	0,63	neutral	-6	neutral	0,16	medium_impact	0,45	medium_impact	0,08	medium_impact	0,35	0,24	0,8	55,97	9,7	N	0,36	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4183	4183	T	G	MI.12585	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	877	293	F	V	Ttc/Gtc	-3,88	0	0	probably_damaging	1	neutral	0,32	neutral	2,65	deleterious	-9,76	deleterious	-6,07	medium_impact	3,15	neutral	0,65	damaging	0,13	deleterious	4,3	24	0,08	0,35	neutral	0,25	disease	0,79	disease	0,61	disease	0,68	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,09	medium_impact	1,56	0,29	0,8	58,81	10,26	N	0,3	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4183	4183	T	A	MI.12586	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	877	293	F	I	Ttc/Atc	-3,88	0	0	probably_damaging	1	neutral	0,27	neutral	2,63	deleterious	-9,7	deleterious	-5,2	medium_impact	2,04	neutral	0,73	damaging	0,16	deleterious	4,74	24,7	0,15	0,45	neutral	0,24	disease	0,81	disease	0,52	disease	0,65	3	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,03	medium_impact	0,59	0,5	0,8	58,81	10,26	N	0,34	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4183	4183	T	C	MI.12587	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	877	293	F	L	Ttc/Ctc	-3,88	0	0	probably_damaging	1	neutral	1	neutral	2,83	deleterious	-8,42	deleterious	-5,2	low_impact	1,68	neutral	0,76	damaging	0,14	deleterious	4,28	24	0,18	0,45	neutral	0,13	disease	0,76	neutral	0,48	disease	0,56	1	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,68	low_impact	-3,57	high_impact	1,96	medium_impact	0,28	0,72	0,85	58,81	10,26	N	0,26	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4184	4184	T	G	MI.12588	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	878	293	F	C	tTc/tGc	7,4	1	0	probably_damaging	1	neutral	0,14	neutral	2,56	deleterious	-11,79	deleterious	-6,96	medium_impact	2,81	neutral	0,71	damaging	0,13	deleterious	4,24	23,9	0,06	0,35	disease	0,65	disease	0,81	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	-0,17	medium_impact	1,27	0,15	0,8	58,81	10,26	N	0,47	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4184	4184	T	C	MI.12589	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	878	293	F	S	tTc/tCc	7,4	1	0	probably_damaging	1	neutral	0,32	neutral	2,57	deleterious	-10,45	deleterious	-6,91	medium_impact	3,04	neutral	0,7	damaging	0,16	deleterious	4,38	24,1	0,03	0,35	neutral	0,45	disease	0,77	disease	0,62	disease	0,68	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	0,09	medium_impact	1,47	0,14	0,8	58,81	10,26	N	0,47	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9117	9117	T	A	MI.1259	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	591	197	I	M	atT/atA	3,83	0,45	0	benign	0,35	neutral	0,29	neutral	4,32	neutral	-2,35	neutral	-0,84	low_impact	1,15	neutral	0,91	neutral	0,92	neutral	0,97	10,48	0,28	0,65	NA	NA	neutral	0,23	neutral	0,27	neutral	0,16	7	neutral	0,65	deleterious	0,47	neutral	-6	neutral	0,43	medium_impact	-0,5	medium_impact	0,07	medium_impact	-0,11	0,49	0,9	24,78	14,04	N	0,46	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4184	4184	T	A	MI.12590	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	878	293	F	Y	tTc/tAc	7,4	1	0	probably_damaging	1	neutral	0,7	neutral	2,64	deleterious	-7,65	deleterious	-2,58	low_impact	1,74	neutral	0,71	damaging	0,15	deleterious	4,36	24,1	0,18	0,45	disease	0,51	neutral	0,42	neutral	0,33	neutral	0,29	4	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,73	low_impact	-3,57	medium_impact	0,48	medium_impact	0,33	0,56	0,8	58,81	10,26	N	0,5	N	0,88	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4185	4185	C	G	MI.12591	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	879	293	F	L	ttC/ttG	7,4	1	0	probably_damaging	1	neutral	1	neutral	2,83	deleterious	-8,42	deleterious	-5,2	low_impact	1,68	neutral	0,76	damaging	0,14	deleterious	4,49	24,3	0,18	0,45	neutral	0,13	disease	0,76	neutral	0,48	disease	0,56	1	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,68	low_impact	-3,57	high_impact	1,96	medium_impact	0,28	0,72	0,85	58,81	10,26	N	0,39	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4185	4185	C	A	MI.12592	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	879	293	F	L	ttC/ttA	7,4	1	0	probably_damaging	1	neutral	1	neutral	2,83	deleterious	-8,42	deleterious	-5,2	low_impact	1,68	neutral	0,76	damaging	0,14	deleterious	4,82	24,8	0,18	0,45	neutral	0,13	disease	0,76	neutral	0,48	disease	0,56	1	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,68	low_impact	-3,57	high_impact	1,96	medium_impact	0,28	0,72	0,85	58,81	10,26	N	0,39	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4186	4186	C	G	MI.12593	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	880	294	L	V	Cta/Gta	-2,73	0	0	probably_damaging	1	neutral	0,35	neutral	1,66	deleterious	-7,96	deleterious	-2,65	medium_impact	3,18	neutral	0,65	damaging	0,11	deleterious	3,52	23,1	0,27	0,45	neutral	0,27	neutral	0,4	disease	0,66	neutral	0,42	2	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,12	medium_impact	1,59	0,46	0,8	60,06	10,16	N	0,33	N	0,84	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4186	4186	C	A	MI.12594	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	880	294	L	M	Cta/Ata	-2,73	0	0	probably_damaging	1	neutral	0,27	neutral	1,62	deleterious	-8,24	neutral	-1,77	medium_impact	3,38	neutral	0,79	damaging	0,16	deleterious	3,85	23,4	0,24	0,45	disease	0,52	neutral	0,46	disease	0,65	neutral	0,5	0	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,03	medium_impact	1,76	0,37	0,8	60,06	10,16	N	0,33	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4187	4187	T	C	MI.12595	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	881	294	L	P	cTa/cCa	-0,43	0	0	probably_damaging	1	neutral	0,21	neutral	1,57	deleterious	-11	deleterious	-6,18	high_impact	3,93	neutral	0,71	damaging	0,1	deleterious	4,02	23,6	0,02	0,35	disease	0,72	disease	0,68	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	-0,05	high_impact	2,24	0,29	0,8	60,06	10,16	N	0,33	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4187	4187	T	A	MI.12596	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	881	294	L	Q	cTa/cAa	-0,43	0	0	probably_damaging	1	neutral	0,24	neutral	1,58	deleterious	-10,85	deleterious	-5,3	high_impact	4,62	neutral	0,7	damaging	0,11	deleterious	4,18	23,8	0,03	0,35	disease	0,64	disease	0,7	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	-0,01	high_impact	2,85	0,29	0,8	60,06	10,16	N	0,44	N	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4187	4187	T	G	MI.12597	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	881	294	L	R	cTa/cGa	-0,43	0	0	probably_damaging	1	neutral	0,22	neutral	1,58	deleterious	-10,71	deleterious	-5,3	high_impact	4,62	neutral	0,71	damaging	0,09	deleterious	4,31	24	0,02	0,35	disease	0,62	disease	0,8	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,83	low_impact	-3,57	medium_impact	-0,03	high_impact	2,85	0,2	0,8	60,06	10,16	N	0,48	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4189	4189	C	A	MI.12598	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	883	295	P	T	Cca/Aca	-10,1	0	0	probably_damaging	1	neutral	0,37	neutral	2,09	deleterious	-11,95	deleterious	-7,02	high_impact	4,16	neutral	0,66	damaging	0,11	deleterious	3,78	23,4	0,11	0,4	neutral	0,41	disease	0,74	disease	0,56	disease	0,65	3	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	0,15	high_impact	2,44	0,54	0,8	59,43	10,47	N	0,3	N	0,91	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4189	4189	C	T	MI.12599	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	883	295	P	S	Cca/Tca	-10,1	0	0	probably_damaging	1	neutral	0,44	neutral	2,14	deleterious	-11,53	deleterious	-7,02	high_impact	3,81	neutral	0,72	damaging	0,14	deleterious	3,99	23,6	0,1	0,4	neutral	0,32	disease	0,71	disease	0,56	disease	0,59	2	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,74	low_impact	-3,57	medium_impact	0,22	high_impact	2,14	0,17	0,8	59,43	10,47	N	0,29	N	0,74	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8585	8585	C	G	MI.126	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	59	20	A	G	gCa/gGa	-1,49	0	0	benign	0,28	neutral	0,33	neutral	4,58	neutral	-2,08	deleterious	-2,85	low_impact	1,1	neutral	0,87	neutral	0,57	deleterious	2	16,19	0,3	0,65	disease	0,72	neutral	0,37	neutral	0,42	disease	0,65	3	neutral	0,6	deleterious	0,53	neutral	-6	neutral	0,36	medium_impact	-0,37	medium_impact	0,12	medium_impact	-0,16	0,52	0,9	24,78	23,03	N	0,38	N	0,53	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9117	9117	T	G	MI.1260	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	591	197	I	M	atT/atG	3,83	0,45	0	benign	0,35	neutral	0,29	neutral	4,32	neutral	-2,35	neutral	-0,84	low_impact	1,15	neutral	0,91	neutral	0,92	deleterious	0,65	8,5	0,28	0,65	NA	NA	neutral	0,23	neutral	0,27	neutral	0,16	7	neutral	0,65	deleterious	0,47	neutral	-6	neutral	0,43	medium_impact	-0,5	medium_impact	0,07	medium_impact	-0,11	0,49	0,9	24,78	14,04	N	0,45	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4189	4189	C	G	MI.12600	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	883	295	P	A	Cca/Gca	-10,1	0	0	probably_damaging	1	neutral	0,48	neutral	2,13	deleterious	-11,19	deleterious	-7,02	high_impact	4,16	neutral	0,7	damaging	0,14	deleterious	3,18	22,7	0,12	0,4	neutral	0,34	disease	0,64	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,73	low_impact	-3,57	medium_impact	0,26	high_impact	2,44	0,54	0,8	59,43	10,47	N	0,31	N	0,78	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4190	4190	C	A	MI.12601	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	884	295	P	Q	cCa/cAa	7,17	1	0	probably_damaging	1	neutral	0,31	neutral	2,06	deleterious	-12,98	deleterious	-7,03	high_impact	4,36	neutral	0,72	damaging	0,11	deleterious	4,21	23,9	0,09	0,35	neutral	0,5	disease	0,83	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,77	low_impact	-3,57	medium_impact	0,08	high_impact	2,62	0,3	0,8	59,43	10,47	P	0,51	P	0,84	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4190	4190	C	T	MI.12602	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	884	295	P	L	cCa/cTa	7,17	1	0	probably_damaging	1	neutral	0,87	neutral	2,06	deleterious	-12,46	deleterious	-8,79	high_impact	3,9	neutral	0,78	damaging	0,11	deleterious	4,42	24,2	0,07	0,35	neutral	0,33	disease	0,87	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,76	low_impact	-3,57	medium_impact	0,74	high_impact	2,22	0,53	0,8	59,43	10,47	N	0,45	N	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4190	4190	C	G	MI.12603	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	884	295	P	R	cCa/cGa	7,17	1	0	probably_damaging	1	neutral	0,33	neutral	2,06	deleterious	-12,49	deleterious	-7,91	high_impact	4,16	neutral	0,81	damaging	0,13	deleterious	3,62	23,2	0,04	0,35	disease	0,51	disease	0,88	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,81	low_impact	-3,57	medium_impact	0,1	high_impact	2,44	0,37	0,8	59,43	10,47	N	0,55	P	0,71	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4192	4192	C	T	MI.12604	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	886	296	L	F	Ctc/Ttc	-14,47	0	0	probably_damaging	0,97	neutral	0,54	neutral	2,27	deleterious	-3,45	deleterious	-2,75	medium_impact	2,05	neutral	0,74	damaging	0,11	deleterious	4,08	23,7	0,2	0,45	neutral	0,34	disease	0,55	neutral	0,32	neutral	0,46	1	neutral	0,97	neutral	0,29	deleterious	1	deleterious	0,71	low_impact	-2,17	medium_impact	0,31	medium_impact	0,6	0,62	0,8	20,44	16,14	N	0,22	N	0,9	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4192	4192	C	A	MI.12605	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	886	296	L	I	Ctc/Atc	-14,47	0	0	possibly_damaging	0,86	neutral	0,31	neutral	2,5	neutral	0,8	neutral	-0,79	low_impact	1,39	neutral	0,88	neutral	0,83	deleterious	2,79	21,3	0,31	0,45	neutral	0,18	neutral	0,25	neutral	0,23	neutral	0,43	1	neutral	0,88	neutral	0,23	neutral	-3	deleterious	0,63	low_impact	-1,49	medium_impact	0,08	medium_impact	0,03	0,58	0,8	20,44	16,14	N	0,43	N	0,1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4192	4192	C	G	MI.12606	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	886	296	L	V	Ctc/Gtc	-14,47	0	0	possibly_damaging	0,86	neutral	0,42	neutral	2,47	neutral	-2,33	neutral	-1,47	medium_impact	2,19	neutral	0,82	damaging	0,18	deleterious	3,5	23,1	0,31	0,45	neutral	0,25	neutral	0,35	neutral	0,27	neutral	0,44	1	neutral	0,85	neutral	0,28	NA	0	deleterious	0,63	low_impact	-1,49	medium_impact	0,2	medium_impact	0,72	0,51	0,8	20,44	16,14	N	0,32	N	0,65	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4193	4193	T	A	MI.12607	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	887	296	L	H	cTc/cAc	-0,89	0	0	probably_damaging	0,99	neutral	0,3	neutral	2,21	deleterious	-7,04	deleterious	-5,21	high_impact	4,24	neutral	0,72	damaging	0,08	deleterious	4,37	24,1	0,06	0,35	disease	0,79	disease	0,79	disease	0,64	disease	0,74	5	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,81	low_impact	-2,62	medium_impact	0,07	high_impact	2,51	0,26	0,8	20,44	16,14	N	0,34	N	0,88	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4193	4193	T	G	MI.12608	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	887	296	L	R	cTc/cGc	-0,89	0	0	probably_damaging	0,98	neutral	0,19	neutral	2,21	deleterious	-6,29	deleterious	-4,55	high_impact	3,9	neutral	0,65	damaging	0,08	deleterious	4,29	24	0,03	0,35	disease	0,72	disease	0,88	disease	0,68	disease	0,75	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-2,34	medium_impact	-0,08	high_impact	2,22	0,24	0,8	20,44	16,14	N	0,33	N	0,98	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4193	4193	T	C	MI.12609	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	887	296	L	P	cTc/cCc	-0,89	0	0	probably_damaging	0,99	neutral	0,17	neutral	2,21	deleterious	-6,63	deleterious	-5,19	high_impact	4,24	neutral	0,64	damaging	0,08	deleterious	4,07	23,7	0,04	0,35	disease	0,78	disease	0,86	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-2,62	medium_impact	-0,11	high_impact	2,51	0,25	0,8	20,44	16,14	N	0,34	N	0,94	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9118	9118	C	G	MI.1261	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	592	198	L	V	Cta/Gta	-12,6	0	0	probably_damaging	0,99	neutral	0,09	neutral	4,31	neutral	-0,11	deleterious	-2,56	medium_impact	2,3	neutral	0,93	neutral	0,54	deleterious	3,48	23,1	0,39	0,65	NA	NA	disease	0,57	neutral	0,37	neutral	0,46	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,82	low_impact	-2,65	medium_impact	-0,28	medium_impact	0,87	0,62	0,9	42,04	7,67	N	0,47	N	0,87	polymorphism	1	0,07	rs28520706	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4195	4195	A	T	MI.12610	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	889	297	T	S	Acc/Tcc	-9,41	0	0	probably_damaging	1	neutral	0,44	neutral	3,02	deleterious	-8,17	deleterious	-3,12	low_impact	1,45	neutral	0,8	damaging	0,16	deleterious	3,39	23	0,33	0,5	neutral	0,11	neutral	0,21	neutral	0,24	neutral	0,33	3	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,66	low_impact	-3,57	medium_impact	0,22	medium_impact	0,08	0,7	0,85	61,32	9,85	N	0,29	N	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4195	4195	A	G	MI.12611	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	889	297	T	A	Acc/Gcc	-9,41	0	0	probably_damaging	1	neutral	0,5	neutral	2,75	deleterious	-7,85	deleterious	-3,87	low_impact	1,75	neutral	0,77	damaging	0,17	deleterious	3,56	23,1	0,22	0,45	neutral	0,13	disease	0,62	neutral	0,31	neutral	0,43	2	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,68	low_impact	-3,57	medium_impact	0,28	medium_impact	0,34	0,37	0,8	61,32	9,85	N	0,22	N	0,65	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4195	4195	A	C	MI.12612	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	889	297	T	P	Acc/Ccc	-9,41	0	0	probably_damaging	1	neutral	0,23	neutral	2,58	deleterious	-9,86	deleterious	-4,9	medium_impact	3,25	neutral	0,73	damaging	0,09	deleterious	3,58	23,2	0,05	0,35	neutral	0,47	disease	0,9	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,79	low_impact	-3,57	medium_impact	-0,02	medium_impact	1,65	0,41	0,8	61,32	9,85	N	0,29	N	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4196	4196	C	A	MI.12613	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	890	297	T	N	aCc/aAc	5,55	1	0	probably_damaging	1	neutral	0,34	neutral	2,6	deleterious	-9,77	deleterious	-4,11	medium_impact	2,98	neutral	0,73	damaging	0,09	deleterious	3,79	23,4	0,23	0,45	neutral	0,23	disease	0,86	disease	0,53	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,11	medium_impact	1,41	0,53	0,8	61,32	9,85	N	0,45	N	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4196	4196	C	T	MI.12614	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	890	297	T	I	aCc/aTc	5,55	1	0	probably_damaging	1	neutral	0,4	neutral	2,59	deleterious	-9,94	deleterious	-4,72	medium_impact	2,32	neutral	0,76	damaging	0,09	deleterious	4,11	23,7	0,1	0,4	neutral	0,27	disease	0,87	neutral	0,5	disease	0,74	5	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,73	low_impact	-3,57	medium_impact	0,18	medium_impact	0,84	0,54	0,8	61,32	9,85	N	0,43	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4196	4196	C	G	MI.12615	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	890	297	T	S	aCc/aGc	5,55	1	0	probably_damaging	1	neutral	0,44	neutral	3,02	deleterious	-8,17	deleterious	-3,12	low_impact	1,45	neutral	0,8	damaging	0,16	deleterious	3,63	23,2	0,33	0,5	neutral	0,11	neutral	0,21	neutral	0,24	neutral	0,33	3	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,66	low_impact	-3,57	medium_impact	0,22	medium_impact	0,08	0,7	0,85	61,32	9,85	N	0,5	N	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4198	4198	C	G	MI.12616	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	892	298	L	V	Cta/Gta	-7,11	0	0	probably_damaging	1	neutral	0,39	neutral	1,91	deleterious	-7,96	neutral	-2,39	medium_impact	3,1	neutral	0,66	damaging	0,05	deleterious	3,54	23,1	0,13	0,4	disease	0,51	disease	0,56	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,75	low_impact	-3,57	medium_impact	0,17	medium_impact	1,52	0,47	0,8	59,75	9,48	N	0,25	N	0,84	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4198	4198	C	A	MI.12617	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	892	298	L	M	Cta/Ata	-7,11	0	0	probably_damaging	1	neutral	0,25	neutral	1,85	deleterious	-8,24	neutral	-1,67	medium_impact	2,88	neutral	0,7	damaging	0,13	deleterious	3,86	23,5	0,14	0,4	neutral	0,48	disease	0,51	disease	0,53	neutral	0,47	1	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,72	low_impact	-3,57	medium_impact	0,01	medium_impact	1,33	0,48	0,8	59,75	9,48	N	0,31	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4199	4199	T	C	MI.12618	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	893	298	L	P	cTa/cCa	-0,2	0	0	probably_damaging	1	neutral	0,18	neutral	1,78	deleterious	-11	deleterious	-6,03	high_impact	4,57	damaging	0,46	damaging	0,04	deleterious	4,02	23,6	0,02	0,35	disease	0,91	disease	0,81	disease	0,74	disease	0,8	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,57	medium_impact	-0,09	high_impact	2,8	0,31	0,8	59,75	9,48	N	0,42	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4199	4199	T	A	MI.12619	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	893	298	L	Q	cTa/cAa	-0,2	0	0	probably_damaging	1	neutral	0,2	neutral	1,79	deleterious	-10,85	deleterious	-5,2	high_impact	4,57	damaging	0,56	damaging	0,04	deleterious	4,18	23,8	0,02	0,35	disease	0,87	disease	0,78	disease	0,64	disease	0,77	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,82	low_impact	-3,57	medium_impact	-0,06	high_impact	2,8	0,29	0,8	59,75	9,48	N	0,39	N	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9118	9118	C	A	MI.1262	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	592	198	L	M	Cta/Ata	-12,6	0	0	probably_damaging	1	neutral	0,17	neutral	4,17	neutral	-2,21	neutral	-1,64	low_impact	1,48	neutral	0,92	neutral	0,85	deleterious	2,69	20,7	0,29	0,65	NA	NA	neutral	0,34	neutral	0,34	neutral	0,16	7	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	-0,1	medium_impact	0,17	0,43	0,9	42,04	7,67	N	0,46	N	0,96	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4199	4199	T	G	MI.12620	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	893	298	L	R	cTa/cGa	-0,2	0	0	probably_damaging	1	neutral	0,25	neutral	1,79	deleterious	-10,71	deleterious	-5,21	high_impact	4,22	damaging	0,51	damaging	0,04	deleterious	4,29	24	0,02	0,35	disease	0,88	disease	0,88	disease	0,75	disease	0,84	7	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,89	low_impact	-3,57	medium_impact	0,01	high_impact	2,5	0,13	0,8	59,75	9,48	N	0,37	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4201	4201	G	A	MI.12621	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	895	299	A	T	Gca/Aca	-1,81	0	0	benign	0,15	neutral	0,38	neutral	2,64	deleterious	-5,23	deleterious	-3,13	medium_impact	3,24	neutral	0,67	neutral	0,59	deleterious	2,37	18,62	0,15	0,45	neutral	0,32	disease	0,67	neutral	0,29	neutral	0,49	0	neutral	0,55	deleterious	0,62	neutral	-3	neutral	0,23	medium_impact	-0,04	medium_impact	0,16	medium_impact	1,64	0,7	0,85	56,92	10,51	N	0,47	N	0,7	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4201	4201	G	T	MI.12622	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	895	299	A	S	Gca/Tca	-1,81	0	0	possibly_damaging	0,78	neutral	0,42	neutral	2,65	deleterious	-5,92	neutral	-2,42	medium_impact	2,31	neutral	0,8	neutral	0,6	deleterious	1,97	16,02	0,22	0,45	neutral	0,34	disease	0,62	neutral	0,27	neutral	0,45	1	neutral	0,78	neutral	0,32	NA	0	deleterious	0,59	low_impact	-1,27	medium_impact	0,2	medium_impact	0,83	0,49	0,8	56,92	10,51	N	0,37	N	0,93	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4201	4201	G	C	MI.12623	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	895	299	A	P	Gca/Cca	-1,81	0	0	probably_damaging	0,96	neutral	0,22	neutral	2,58	deleterious	-7,92	deleterious	-4,08	high_impact	3,94	neutral	0,69	neutral	0,37	deleterious	3,61	23,2	0,05	0,35	disease	0,58	disease	0,86	disease	0,56	disease	0,71	4	neutral	0,97	neutral	0,13	deleterious	2	deleterious	0,8	low_impact	-2,05	medium_impact	-0,03	high_impact	2,25	0,56	0,8	56,92	10,51	N	0,43	N	0,96	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4202	4202	C	A	MI.12624	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	896	299	A	E	gCa/gAa	5,09	1	0	probably_damaging	0,93	neutral	0,2	neutral	2,64	deleterious	-8,42	deleterious	-4,1	high_impact	3,94	neutral	0,73	neutral	0,4	deleterious	3,05	22,4	0,04	0,35	neutral	0,42	disease	0,84	disease	0,55	disease	0,72	4	neutral	0,96	neutral	0,14	deleterious	2	deleterious	0,73	low_impact	-1,81	medium_impact	-0,06	high_impact	2,25	0,46	0,8	56,92	10,51	P	0,61	P	0,96	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4202	4202	C	T	MI.12625	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	896	299	A	V	gCa/gTa	5,09	1	0	possibly_damaging	0,78	neutral	0,48	neutral	2,66	deleterious	-6,18	deleterious	-3,07	low_impact	1,67	neutral	0,84	neutral	0,82	deleterious	2,65	20,5	0,2	0,45	neutral	0,19	disease	0,68	neutral	0,39	neutral	0,48	0	neutral	0,77	neutral	0,35	neutral	-3	deleterious	0,56	low_impact	-1,27	medium_impact	0,26	medium_impact	0,27	0,74	0,85	56,92	10,51	P	0,54	P	0,72	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4202	4202	C	G	MI.12626	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	896	299	A	G	gCa/gGa	5,09	1	0	possibly_damaging	0,78	neutral	0,26	neutral	2,67	deleterious	-6,68	deleterious	-3,31	medium_impact	2,08	neutral	0,74	neutral	0,6	deleterious	2,2	17,52	0,23	0,45	neutral	0,37	disease	0,55	neutral	0,25	neutral	0,45	1	neutral	0,84	neutral	0,24	NA	0	deleterious	0,6	low_impact	-1,27	medium_impact	0,02	medium_impact	0,63	0,66	0,8	56,92	10,51	P	0,58	P	0,79	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4204	4204	T	G	MI.12627	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	898	300	L	V	Tta/Gta	-4,81	0	0	benign	0,13	neutral	0,25	neutral	2,74	deleterious	-5,5	neutral	-2,02	low_impact	1,6	neutral	0,7	neutral	0,58	neutral	1,63	13,99	0,29	0,45	neutral	0,18	disease	0,53	neutral	0,49	neutral	0,48	0	neutral	0,71	deleterious	0,56	neutral	-6	neutral	0,19	medium_impact	0,02	medium_impact	0,01	medium_impact	0,21	0,41	0,8	24,21	11,8	N	0,4	N	0,33	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4204	4204	T	A	MI.12628	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	898	300	L	M	Tta/Ata	-4,81	0	0	benign	0,04	neutral	0,2	neutral	2,69	deleterious	-3,01	neutral	-0,64	low_impact	1,18	neutral	0,85	neutral	0,9	deleterious	1,84	15,25	0,23	0,45	neutral	0,26	neutral	0,17	neutral	0,23	neutral	0,29	4	neutral	0,79	deleterious	0,58	neutral	-6	neutral	0,14	medium_impact	0,55	medium_impact	-0,06	medium_impact	-0,16	0,36	0,8	24,21	11,8	N	0,51	P	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4205	4205	T	C	MI.12629	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	899	300	L	S	tTa/tCa	-2,27	0	0	benign	0,01	neutral	0,21	neutral	2,69	deleterious	-8,8	deleterious	-4,33	medium_impact	2,45	neutral	0,76	neutral	0,61	deleterious	1,94	15,81	0,09	0,4	neutral	0,29	disease	0,67	neutral	0,5	disease	0,52	0	neutral	0,79	deleterious	0,6	neutral	-3	neutral	0,19	medium_impact	1,12	medium_impact	-0,05	medium_impact	0,95	0,27	0,8	24,21	11,8	N	0,41	N	0,2	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9119	9119	T	A	MI.1263	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	593	198	L	Q	cTa/cAa	-4,5	0	0	probably_damaging	1	deleterious	0,01	neutral	4,13	deleterious	-3,24	deleterious	-5,19	medium_impact	2,73	neutral	0,8	neutral	0,44	deleterious	4,08	23,7	0,18	0,65	NA	NA	disease	0,73	disease	0,58	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,82	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,24	0,59	0,9	42,04	7,67	N	0,31	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4205	4205	T	G	MI.12630	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	899	300	L	W	tTa/tGa	-2,27	0	0	possibly_damaging	0,84	neutral	0,1	neutral	2,66	deleterious	-9,5	deleterious	-4,33	medium_impact	2,06	neutral	0,68	neutral	0,43	deleterious	3,51	23,1	0,07	0,35	neutral	0,32	disease	0,72	neutral	0,32	disease	0,53	1	neutral	0,95	neutral	0,13	NA	0	deleterious	0,66	low_impact	-1,43	medium_impact	-0,26	medium_impact	0,61	0,18	0,8	24,21	11,8	N	0,43	N	0,81	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4206	4206	A	C	MI.12631	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	900	300	L	F	ttA/ttC	4,63	0,67	0	benign	0,01	neutral	0,61	neutral	2,71	deleterious	-6,03	deleterious	-2,7	low_impact	0,92	neutral	0,83	neutral	0,93	deleterious	0,73	9,02	0,27	0,45	neutral	0,17	neutral	0,33	neutral	0,23	neutral	0,44	1	neutral	0,38	deleterious	0,8	neutral	-6	neutral	0,15	medium_impact	1,12	medium_impact	0,38	medium_impact	-0,39	0,4	0,8	24,21	11,8	N	0,39	N	0,15	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4206	4206	A	T	MI.12632	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	900	300	L	F	ttA/ttT	4,63	0,67	0	benign	0,01	neutral	0,61	neutral	2,71	deleterious	-6,03	deleterious	-2,7	low_impact	0,92	neutral	0,83	neutral	0,93	deleterious	0,87	9,89	0,27	0,45	neutral	0,17	neutral	0,33	neutral	0,23	neutral	0,44	1	neutral	0,38	deleterious	0,8	neutral	-6	neutral	0,15	medium_impact	1,12	medium_impact	0,38	medium_impact	-0,39	0,4	0,8	24,21	11,8	N	0,38	N	0,15	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4207	4207	C	G	MI.12633	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	901	301	L	V	Ctt/Gtt	-1,58	0	0	benign	0,32	neutral	0,35	neutral	2,63	neutral	-1,2	neutral	0,61	low_impact	0,93	neutral	0,78	neutral	0,76	neutral	1,52	13,43	0,27	0,45	neutral	0,14	neutral	0,14	neutral	0,29	neutral	0,27	5	neutral	0,58	deleterious	0,52	neutral	-6	neutral	0,25	medium_impact	-0,44	medium_impact	0,12	medium_impact	-0,38	0,57	0,8	21,7	31,14	N	0,43	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4207	4207	C	A	MI.12634	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	901	301	L	I	Ctt/Att	-1,58	0	0	benign	0,32	neutral	0,36	neutral	2,53	neutral	-1,47	neutral	0,53	neutral_impact	0,41	neutral	0,74	neutral	0,72	deleterious	2,67	20,6	0,3	0,45	neutral	0,18	neutral	0,34	neutral	0,27	neutral	0,45	1	neutral	0,57	deleterious	0,52	neutral	-6	neutral	0,39	medium_impact	-0,44	medium_impact	0,14	medium_impact	-0,83	0,43	0,8	21,7	31,14	N	0,46	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4207	4207	C	T	MI.12635	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	901	301	L	F	Ctt/Ttt	-1,58	0	0	possibly_damaging	0,85	neutral	0,65	neutral	2,44	neutral	-2,71	neutral	-0,82	low_impact	0,9	neutral	0,78	neutral	0,73	deleterious	2,9	21,9	0,2	0,45	neutral	0,32	neutral	0,47	neutral	0,35	neutral	0,47	1	neutral	0,82	neutral	0,4	neutral	-3	deleterious	0,63	low_impact	-1,46	medium_impact	0,43	medium_impact	-0,4	0,47	0,8	21,7	31,14	N	0,24	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4208	4208	T	A	MI.12636	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	902	301	L	H	cTt/cAt	1,18	0,85	0	probably_damaging	0,94	neutral	0,31	neutral	2,38	deleterious	-4,3	neutral	-2,44	medium_impact	3,37	neutral	0,72	neutral	0,61	deleterious	4,31	24	0,05	0,35	disease	0,6	disease	0,67	disease	0,63	disease	0,72	4	neutral	0,95	neutral	0,19	deleterious	1	deleterious	0,74	low_impact	-1,87	medium_impact	0,08	medium_impact	1,76	0,25	0,8	21,7	31,14	N	0,4	N	0,79	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4208	4208	T	G	MI.12637	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	902	301	L	R	cTt/cGt	1,18	0,85	0	probably_damaging	0,92	neutral	0,2	neutral	2,39	deleterious	-3,4	neutral	-2,42	medium_impact	3,37	neutral	0,74	neutral	0,54	deleterious	4,29	24	0,02	0,35	disease	0,52	disease	0,86	disease	0,68	disease	0,8	6	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,8	low_impact	-1,75	medium_impact	-0,06	medium_impact	1,76	0,22	0,8	21,7	31,14	N	0,39	N	0,85	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4208	4208	T	C	MI.12638	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	902	301	L	P	cTt/cCt	1,18	0,85	0	probably_damaging	0,92	neutral	0,35	neutral	2,38	deleterious	-3,35	neutral	-2,36	medium_impact	3,37	neutral	0,67	neutral	0,45	deleterious	4,05	23,7	0,02	0,35	disease	0,6	disease	0,85	disease	0,68	disease	0,8	6	neutral	0,93	neutral	0,22	deleterious	1	deleterious	0,81	low_impact	-1,75	medium_impact	0,12	medium_impact	1,76	0,34	0,8	21,7	31,14	N	0,36	N	0,94	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4210	4210	A	T	MI.12639	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	904	302	M	L	Ata/Tta	-6,88	0	0	probably_damaging	0,98	neutral	1	neutral	3,03	neutral	5,92	neutral	0,65	neutral_impact	-0,58	neutral	0,86	neutral	0,88	deleterious	0,66	8,53	0,18	0,45	neutral	0,14	neutral	0,29	neutral	0,3	neutral	0,43	1	deleterious	0,98	deleterious	0,51	neutral	-2	deleterious	0,61	low_impact	-2,34	high_impact	1,96	low_impact	-1,7	0,23	0,8	18,87	23,08	N	0,28	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9119	9119	T	C	MI.1264	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	593	198	L	P	cTa/cCa	-4,5	0	0	probably_damaging	1	deleterious	0,01	neutral	4,21	neutral	-2,97	deleterious	-6,12	medium_impact	2,73	neutral	0,77	neutral	0,4	deleterious	3,93	23,5	0,18	0,65	NA	NA	disease	0,83	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,9	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,24	0,71	0,9	42,04	7,67	N	0,3	N	1	disease_causing	0,94	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4210	4210	A	G	MI.12640	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	904	302	M	V	Ata/Gta	-6,88	0	0	probably_damaging	0,99	neutral	0,3	neutral	2,95	neutral	-0,26	neutral	-0,36	low_impact	0,94	neutral	0,8	damaging	0,25	neutral	1,59	13,8	0,18	0,45	neutral	0,1	disease	0,55	neutral	0,4	neutral	0,45	1	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,65	low_impact	-2,62	medium_impact	0,07	medium_impact	-0,37	0,2	0,8	18,87	23,08	N	0,27	N	0,82	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4210	4210	A	C	MI.12641	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	904	302	M	L	Ata/Cta	-6,88	0	0	probably_damaging	0,98	neutral	1	neutral	3,03	neutral	5,92	neutral	0,65	neutral_impact	-0,58	neutral	0,86	neutral	0,88	deleterious	0,55	7,82	0,18	0,45	neutral	0,14	neutral	0,29	neutral	0,3	neutral	0,43	1	deleterious	0,98	deleterious	0,51	neutral	-2	deleterious	0,61	low_impact	-2,34	high_impact	1,96	low_impact	-1,7	0,23	0,8	18,87	23,08	N	0,26	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4211	4211	T	C	MI.12642	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	905	302	M	T	aTa/aCa	0,95	0,3	0	probably_damaging	1	neutral	0,49	neutral	2,81	neutral	-2,58	neutral	-2,43	low_impact	1,49	neutral	0,85	neutral	0,57	deleterious	2,95	22	0,09	0,35	neutral	0,22	disease	0,53	neutral	0,45	neutral	0,48	0	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,68	low_impact	-3,57	medium_impact	0,27	medium_impact	0,11	0,14	0,8	18,87	23,08	N	0,27	N	0,9	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4211	4211	T	A	MI.12643	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	905	302	M	K	aTa/aAa	0,95	0,3	0	probably_damaging	1	neutral	0,27	neutral	2,77	deleterious	-4,1	deleterious	-3,45	medium_impact	3,13	neutral	0,62	damaging	0,11	deleterious	4,02	23,6	0,03	0,35	neutral	0,39	disease	0,8	disease	0,67	disease	0,77	5	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,77	low_impact	-3,57	medium_impact	0,03	medium_impact	1,55	0,15	0,8	18,87	23,08	N	0,31	N	0,95	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4212	4212	A	C	MI.12644	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	906	302	M	I	atA/atC	3,71	0,64	0	probably_damaging	0,99	neutral	0,54	neutral	2,88	neutral	0,79	neutral	0,26	neutral_impact	0,11	neutral	0,69	neutral	0,32	neutral	1,47	13,15	0,18	0,45	neutral	0,13	neutral	0,26	neutral	0,32	neutral	0,42	2	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,64	low_impact	-2,62	medium_impact	0,31	low_impact	-1,09	0,28	0,8	18,87	23,08	N	0,34	N	0,87	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4212	4212	A	T	MI.12645	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	906	302	M	I	atA/atT	3,71	0,64	0	probably_damaging	0,99	neutral	0,54	neutral	2,88	neutral	0,79	neutral	0,26	neutral_impact	0,11	neutral	0,69	neutral	0,32	neutral	1,44	12,98	0,18	0,45	neutral	0,13	neutral	0,26	neutral	0,32	neutral	0,42	2	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,64	low_impact	-2,62	medium_impact	0,31	low_impact	-1,09	0,28	0,8	18,87	23,08	N	0,35	N	0,87	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4213	4213	T	C	MI.12646	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	907	303	W	R	Tga/Cga	-0,43	0,28	0	probably_damaging	1	neutral	0,22	neutral	2,78	deleterious	-8,45	deleterious	-10,49	medium_impact	3,42	neutral	0,7	damaging	0,11	deleterious	3,68	23,3	0,06	0,35	neutral	0,32	disease	0,84	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,76	low_impact	-3,57	medium_impact	-0,03	medium_impact	1,8	0,17	0,8	58,81	9,14	N	0,36	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4213	4213	T	G	MI.12647	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	907	303	W	G	Tga/Gga	-0,43	0,28	0	probably_damaging	1	neutral	0,32	neutral	2,78	deleterious	-8,71	deleterious	-9,87	medium_impact	2,27	neutral	0,77	damaging	0,15	deleterious	3,99	23,6	0,08	0,35	neutral	0,28	disease	0,72	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,7	low_impact	-3,57	medium_impact	0,09	medium_impact	0,79	0,19	0,8	58,81	9,14	N	0,28	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4214	4214	G	C	MI.12648	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	908	303	W	S	tGa/tCa	1,87	0,98	0	probably_damaging	1	neutral	0,35	neutral	2,81	deleterious	-8,22	deleterious	-10,42	medium_impact	2,31	neutral	0,78	damaging	0,16	deleterious	4,13	23,8	0,09	0,35	neutral	0,2	disease	0,77	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,71	low_impact	-3,57	medium_impact	0,12	medium_impact	0,83	0,18	0,8	58,81	9,14	N	0,37	N	0,98	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4214	4214	G	T	MI.12649	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	908	303	W	L	tGa/tTa	1,87	0,98	0	probably_damaging	1	neutral	1	neutral	2,98	deleterious	-3,82	deleterious	-9,29	neutral_impact	0,27	neutral	0,82	neutral	0,59	deleterious	3,27	22,8	0,1	0,4	neutral	0,09	disease	0,53	neutral	0,44	neutral	0,43	1	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,67	low_impact	-3,57	high_impact	1,96	medium_impact	-0,95	0,11	0,8	58,81	9,14	N	0,35	N	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9119	9119	T	G	MI.1265	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	593	198	L	R	cTa/cGa	-4,5	0	0	probably_damaging	1	deleterious	0,01	neutral	4,13	deleterious	-3,22	deleterious	-5,22	high_impact	3,82	neutral	0,79	neutral	0,39	deleterious	4,17	23,8	0,16	0,65	NA	NA	disease	0,88	disease	0,7	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,91	low_impact	-3,6	medium_impact	-0,84	high_impact	2,18	0,66	0,9	42,04	7,67	N	0,34	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4215	4215	A	C	MI.12650	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	909	303	W	C	tgA/tgC	1,64	0,99	0	probably_damaging	1	neutral	0,17	neutral	2,77	deleterious	-9,57	deleterious	-9,56	low_impact	1,68	neutral	0,78	damaging	0,11	deleterious	4,15	23,8	0,09	0,35	neutral	0,41	disease	0,8	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,72	low_impact	-3,57	medium_impact	-0,11	medium_impact	0,28	0,16	0,8	58,81	9,14	N	0,34	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4215	4215	A	T	MI.12651	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	909	303	W	C	tgA/tgT	1,64	0,99	0	probably_damaging	1	neutral	0,17	neutral	2,77	deleterious	-9,57	deleterious	-9,56	low_impact	1,68	neutral	0,78	damaging	0,11	deleterious	4,22	23,9	0,09	0,35	neutral	0,41	disease	0,8	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,72	low_impact	-3,57	medium_impact	-0,11	medium_impact	0,28	0,16	0,8	58,81	9,14	N	0,35	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4216	4216	T	C	MI.12652	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	910	304	Y	H	Tat/Cat	2,56	0,98	0,22	benign	0,01	neutral	0,37	neutral	2,8	neutral	2,95	neutral	3,51	neutral_impact	-1,19	damaging	0,33	neutral	0,97	neutral	-0,95	0,02	0,15	0,4	neutral	0,11	neutral	0,1	neutral	0,3	neutral	0,22	6	neutral	0,62	deleterious	0,68	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,15	low_impact	-2,23	0,3	0,8	29,25	30	P	0,73	P	0,03	polymorphism	1	0,01	rs1599988	other	Leber's_optic_atrophy	RCV000010373.6	MedGen:OMIM:SNOMED_CT	acute leukemia platelets, leukocytes & bone marrow	COSM1138370	.	.	T4216C	LHON/Insulin Resistance/possible adaptive high altitude variant	+	-	P.M.-haplogroup J/T marker	36
chrM	4216	4216	T	A	MI.12653	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	910	304	Y	N	Tat/Aat	2,56	0,98	0,22	benign	0,02	neutral	0,15	neutral	2,77	deleterious	-4,94	neutral	-1,66	neutral_impact	0,77	neutral	0,79	neutral	0,86	deleterious	2,22	17,64	0,15	0,4	neutral	0,24	disease	0,6	neutral	0,39	neutral	0,46	1	neutral	0,85	deleterious	0,57	neutral	-6	neutral	0,17	medium_impact	0,84	medium_impact	-0,15	medium_impact	-0,52	0,28	0,8	29,25	30	N	0,52	P	0,47	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4216	4216	T	G	MI.12654	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	910	304	Y	D	Tat/Gat	2,56	0,98	0,22	benign	0,36	neutral	0,08	neutral	2,76	deleterious	-5,99	deleterious	-3,26	medium_impact	2,21	neutral	0,74	neutral	0,41	deleterious	2,27	18	0,08	0,35	neutral	0,29	disease	0,8	disease	0,6	disease	0,77	5	neutral	0,91	neutral	0,36	neutral	-3	neutral	0,3	medium_impact	-0,52	medium_impact	-0,32	medium_impact	0,74	0,26	0,8	29,25	30	N	0,51	P	0,68	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4217	4217	A	C	MI.12655	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	911	304	Y	S	tAt/tCt	-0,2	0,76	0	benign	0,03	neutral	0,21	neutral	2,8	deleterious	-4,78	deleterious	-3,12	neutral_impact	0,37	neutral	0,73	neutral	0,83	deleterious	1,9	15,58	0,09	0,35	neutral	0,15	disease	0,63	neutral	0,48	disease	0,5	0	neutral	0,78	deleterious	0,59	neutral	-6	neutral	0,16	medium_impact	0,67	medium_impact	-0,05	medium_impact	-0,87	0,29	0,8	29,25	30	N	0,36	N	0,07	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4217	4217	A	T	MI.12656	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	911	304	Y	F	tAt/tTt	-0,2	0,76	0	possibly_damaging	0,52	neutral	0,55	neutral	2,84	neutral	-0,44	deleterious	-2,54	neutral_impact	-0,22	neutral	0,82	neutral	0,96	neutral	1,5	13,32	0,25	0,45	neutral	0,14	neutral	0,38	neutral	0,26	neutral	0,43	1	neutral	0,48	deleterious	0,52	neutral	-3	neutral	0,31	medium_impact	-0,78	medium_impact	0,32	low_impact	-1,38	0,42	0,8	29,25	30	N	0,25	N	0,09	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4217	4217	A	G	MI.12657	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	911	304	Y	C	tAt/tGt	-0,2	0,76	0	possibly_damaging	0,89	neutral	0,17	neutral	2,75	deleterious	-6,38	deleterious	-4,6	low_impact	1,52	neutral	0,83	neutral	0,47	deleterious	3,27	22,8	0,08	0,35	neutral	0,34	disease	0,76	disease	0,51	disease	0,62	2	neutral	0,94	neutral	0,14	neutral	-3	deleterious	0,67	low_impact	-1,6	medium_impact	-0,11	medium_impact	0,14	0,08	0,8	29,25	30	N	0,39	N	0,66	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4219	4219	G	T	MI.12658	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	913	305	V	F	Gtc/Ttc	-5,5	0	0	benign	0,16	neutral	0,43	neutral	2,7	deleterious	-3	neutral	-1,95	neutral_impact	0,65	neutral	0,76	neutral	0,63	deleterious	1,95	15,88	0,06	0,35	neutral	0,27	disease	0,63	neutral	0,25	neutral	0,43	1	neutral	0,49	deleterious	0,64	neutral	-6	neutral	0,16	medium_impact	-0,08	medium_impact	0,21	medium_impact	-0,62	0,36	0,8	23,27	23,47	N	0,36	N	0,65	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4219	4219	G	C	MI.12659	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	913	305	V	L	Gtc/Ctc	-5,5	0	0	benign	0	neutral	1	neutral	2,77	neutral	-1,49	neutral	0,01	neutral_impact	0,38	neutral	0,81	neutral	0,67	neutral	-0,55	0,16	0,22	0,45	neutral	0,14	neutral	0,23	neutral	0,2	neutral	0,4	2	neutral	0	deleterious	1	neutral	-6	neutral	0,08	high_impact	2,07	high_impact	1,96	medium_impact	-0,86	0,52	0,8	23,27	23,47	N	0,3	N	0,39	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9121	9121	C	A	MI.1266	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	595	199	L	M	Ctg/Atg	-6,58	0	0	probably_damaging	1	deleterious	0,02	neutral	4,06	neutral	-1,13	neutral	-1,76	medium_impact	2,37	damaging	0,54	damaging	0,12	deleterious	3,89	23,5	0,34	0,65	NA	NA	neutral	0,48	disease	0,53	neutral	0,4	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-3,6	medium_impact	-0,66	medium_impact	0,93	0,59	0,9	50	8,81	N	0,3	N	0,96	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4219	4219	G	A	MI.12660	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	913	305	V	I	Gtc/Atc	-5,5	0	0	benign	0	neutral	0,48	neutral	2,81	neutral	-0,42	neutral	0,24	neutral_impact	-1,02	neutral	0,73	neutral	0,94	neutral	-0,86	0,03	0,35	0,5	neutral	0,11	neutral	0,1	neutral	0,17	neutral	0,26	5	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,26	low_impact	-2,08	0,77	0,85	23,27	23,47	N	0,42	N	0,03	polymorphism	1	0,01	rs878853008	Likely benign	not_provided	RCV000224714.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	4220	4220	T	A	MI.12661	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	914	305	V	D	gTc/gAc	0,03	0	0	benign	0,21	neutral	0,06	neutral	2,7	deleterious	-4,11	deleterious	-3,92	medium_impact	2,21	neutral	0,77	neutral	0,44	deleterious	2,67	20,6	0,02	0,35	neutral	0,44	disease	0,73	disease	0,6	disease	0,73	5	neutral	0,93	neutral	0,43	neutral	-3	neutral	0,24	medium_impact	-0,21	medium_impact	-0,4	medium_impact	0,74	0,1	0,8	23,27	23,47	N	0,34	N	0,84	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4220	4220	T	G	MI.12662	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	914	305	V	G	gTc/gGc	0,03	0	0	benign	0,1	neutral	0,16	neutral	2,7	deleterious	-3,26	deleterious	-4,34	neutral_impact	0,14	neutral	0,73	neutral	0,46	deleterious	2,01	16,27	0,05	0,35	neutral	0,28	disease	0,53	neutral	0,42	neutral	0,5	0	neutral	0,82	deleterious	0,53	neutral	-6	neutral	0,15	medium_impact	0,15	medium_impact	-0,13	low_impact	-1,07	0,24	0,8	23,27	23,47	N	0,38	N	0,86	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4220	4220	T	C	MI.12663	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	914	305	V	A	gTc/gCc	0,03	0	0	benign	0	neutral	0,51	neutral	2,88	neutral	-1,35	neutral	-2,01	neutral_impact	-0,3	neutral	0,82	neutral	0,73	deleterious	0,56	7,9	0,16	0,45	neutral	0,13	neutral	0,27	neutral	0,39	neutral	0,42	2	neutral	0,49	deleterious	0,76	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,29	low_impact	-1,45	0,31	0,8	23,27	23,47	N	0,3	N	0,49	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4222	4222	T	C	MI.12664	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	916	306	S	P	Tcc/Ccc	-11,71	0	0	probably_damaging	0,93	neutral	0,21	neutral	2,65	deleterious	-5,25	deleterious	-3,33	medium_impact	3,11	neutral	0,61	neutral	0,37	deleterious	4,05	23,7	0,05	0,35	neutral	0,45	disease	0,85	disease	0,71	disease	0,77	5	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,78	low_impact	-1,81	medium_impact	-0,05	medium_impact	1,53	0,37	0,8	54,72	12,76	N	0,28	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4222	4222	T	A	MI.12665	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	916	306	S	T	Tcc/Acc	-11,71	0	0	benign	0,08	neutral	0,38	neutral	2,72	neutral	-1,43	neutral	-1,67	low_impact	1,41	neutral	0,88	neutral	0,98	deleterious	2,57	19,91	0,17	0,45	neutral	0,25	neutral	0,4	neutral	0,37	neutral	0,44	1	neutral	0,57	deleterious	0,65	neutral	-6	neutral	0,17	medium_impact	0,25	medium_impact	0,16	medium_impact	0,04	0,58	0,8	54,72	12,76	N	0,41	N	0,55	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4222	4222	T	G	MI.12666	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	916	306	S	A	Tcc/Gcc	-11,71	0	0	benign	0,05	neutral	0,44	neutral	2,78	neutral	-1,68	neutral	-1,07	neutral_impact	0,8	neutral	0,87	neutral	0,98	deleterious	1,98	16,08	0,21	0,45	neutral	0,15	neutral	0,19	neutral	0,34	neutral	0,34	3	neutral	0,52	deleterious	0,7	neutral	-6	neutral	0,14	medium_impact	0,45	medium_impact	0,22	medium_impact	-0,49	0,54	0,8	54,72	12,76	N	0,41	N	0,17	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4223	4223	C	A	MI.12667	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	917	306	S	Y	tCc/tAc	0,26	0	0	probably_damaging	0,95	neutral	0,7	neutral	2,66	deleterious	-5,38	deleterious	-4,05	medium_impact	2,42	neutral	0,71	neutral	0,46	deleterious	4,18	23,8	0,06	0,35	disease	0,54	disease	0,77	disease	0,53	disease	0,66	3	neutral	0,94	neutral	0,38	deleterious	1	deleterious	0,75	low_impact	-1,95	medium_impact	0,48	medium_impact	0,93	0,33	0,8	54,72	12,76	N	0,24	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4223	4223	C	G	MI.12668	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	917	306	S	C	tCc/tGc	0,26	0	0	probably_damaging	0,96	neutral	0,16	neutral	2,65	deleterious	-5,91	deleterious	-3,05	medium_impact	2,17	neutral	0,62	neutral	0,39	deleterious	3,66	23,2	0,07	0,35	disease	0,56	disease	0,72	neutral	0,4	disease	0,52	0	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,73	low_impact	-2,05	medium_impact	-0,13	medium_impact	0,71	0,47	0,8	54,72	12,76	N	0,39	N	0,54	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4223	4223	C	T	MI.12669	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	917	306	S	F	tCc/tTc	0,26	0	0	possibly_damaging	0,87	neutral	0,65	neutral	2,69	deleterious	-5,13	deleterious	-4,01	medium_impact	2,07	neutral	0,65	neutral	0,44	deleterious	4,36	24,1	0,05	0,35	disease	0,51	disease	0,81	disease	0,52	disease	0,7	4	neutral	0,85	neutral	0,39	NA	0	deleterious	0,71	low_impact	-1,53	medium_impact	0,43	medium_impact	0,62	0,23	0,8	54,72	12,76	N	0,26	N	1	polymorphism	1	0,09	rs9629043	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9121	9121	C	G	MI.1267	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	595	199	L	V	Ctg/Gtg	-6,58	0	0	probably_damaging	0,99	deleterious	0,01	neutral	4,18	neutral	-1,5	deleterious	-2,66	medium_impact	2,9	damaging	0,45	damaging	0,09	deleterious	3,57	23,1	0,33	0,65	NA	NA	disease	0,59	disease	0,63	disease	0,57	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-2,65	medium_impact	-0,84	medium_impact	1,39	0,43	0,9	50	8,81	N	0,29	N	0,87	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4225	4225	A	G	MI.12670	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	919	307	M	V	Ata/Gta	-5,96	0	0	benign	0	neutral	0,48	neutral	2,96	neutral	-2,09	neutral	-0,9	low_impact	0,93	neutral	0,88	neutral	0,87	neutral	-0,07	1,99	0,26	0,45	neutral	0,07	disease	0,5	neutral	0,41	neutral	0,45	1	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,26	medium_impact	-0,38	0,3	0,8	27,99	23,94	N	0,32	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4225	4225	A	T	MI.12671	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	919	307	M	L	Ata/Tta	-5,96	0	0	benign	0	neutral	1	neutral	3,23	neutral	2,94	neutral	0,56	neutral_impact	-0,64	neutral	0,73	neutral	0,99	neutral	-1,04	0,01	0,3	0,45	neutral	0,14	neutral	0,2	neutral	0,33	neutral	0,33	4	neutral	0	deleterious	1	neutral	-6	neutral	0,08	high_impact	2,07	high_impact	1,96	low_impact	-1,75	0,19	0,8	27,99	23,94	N	0,36	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4225	4225	A	C	MI.12672	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	919	307	M	L	Ata/Cta	-5,96	0	0	benign	0	neutral	1	neutral	3,23	neutral	2,94	neutral	0,56	neutral_impact	-0,64	neutral	0,73	neutral	0,99	neutral	-1,18	0,01	0,3	0,45	neutral	0,14	neutral	0,2	neutral	0,33	neutral	0,33	4	neutral	0	deleterious	1	neutral	-6	neutral	0,08	high_impact	2,07	high_impact	1,96	low_impact	-1,75	0,19	0,8	27,99	23,94	N	0,36	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4226	4226	T	A	MI.12673	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	920	307	M	K	aTa/aAa	-1,81	0	0	benign	0,04	neutral	0,17	neutral	2,73	deleterious	-5,61	deleterious	-3,43	medium_impact	2,79	neutral	0,69	neutral	0,41	deleterious	2,12	17	0,04	0,35	neutral	0,42	disease	0,72	disease	0,66	disease	0,75	5	neutral	0,82	deleterious	0,57	neutral	-3	neutral	0,24	medium_impact	0,55	medium_impact	-0,11	medium_impact	1,25	0,13	0,8	27,99	23,94	N	0,38	N	0,8	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4226	4226	T	C	MI.12674	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	920	307	M	T	aTa/aCa	-1,81	0	0	benign	0	neutral	0,18	neutral	2,76	deleterious	-4,08	neutral	-2,49	low_impact	1,34	neutral	0,83	neutral	0,96	deleterious	0	2,59	0,13	0,4	neutral	0,26	neutral	0,45	neutral	0,42	neutral	0,46	1	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	-0,09	medium_impact	-0,02	0,12	0,8	27,99	23,94	N	0,43	N	0,41	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4227	4227	A	T	MI.12675	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	921	307	M	I	atA/atT	3,02	0,61	0	benign	0	neutral	0,52	neutral	2,93	neutral	-0,74	neutral	-0,37	neutral_impact	0,74	neutral	0,88	neutral	0,99	deleterious	0,45	7,05	0,3	0,45	neutral	0,1	neutral	0,47	neutral	0,37	neutral	0,44	1	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,29	medium_impact	-0,54	0,3	0,8	27,99	23,94	N	0,34	N	0,05	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4227	4227	A	C	MI.12676	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	921	307	M	I	atA/atC	3,02	0,61	0	benign	0	neutral	0,52	neutral	2,93	neutral	-0,74	neutral	-0,37	neutral_impact	0,74	neutral	0,88	neutral	0,99	deleterious	0,36	6,3	0,3	0,45	neutral	0,1	neutral	0,47	neutral	0,37	neutral	0,44	1	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,29	medium_impact	-0,54	0,3	0,8	27,99	23,94	N	0,34	N	0,05	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4228	4228	C	A	MI.12677	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	922	308	P	T	Ccc/Acc	-10,33	0	0	possibly_damaging	0,75	neutral	0,4	neutral	2,82	deleterious	-8,83	deleterious	-6,32	medium_impact	2,29	neutral	0,79	neutral	0,54	deleterious	1,88	15,44	0,19	0,45	neutral	0,13	disease	0,63	neutral	0,36	neutral	0,46	1	neutral	0,76	neutral	0,33	NA	0	deleterious	0,48	low_impact	-1,2	medium_impact	0,18	medium_impact	0,81	0,51	0,8	25,16	10,14	N	0,31	N	0,9	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4228	4228	C	T	MI.12678	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	922	308	P	S	Ccc/Tcc	-10,33	0	0	benign	0,18	neutral	0,46	neutral	2,84	deleterious	-8,39	deleterious	-6,32	medium_impact	2,21	neutral	0,74	neutral	0,65	neutral	0,96	10,4	0,22	0,45	neutral	0,09	disease	0,59	neutral	0,35	neutral	0,44	1	neutral	0,45	deleterious	0,64	neutral	-3	neutral	0,19	medium_impact	-0,13	medium_impact	0,24	medium_impact	0,74	0,2	0,8	25,16	10,14	N	0,36	N	0,7	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4228	4228	C	G	MI.12679	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	922	308	P	A	Ccc/Gcc	-10,33	0	0	possibly_damaging	0,51	neutral	0,53	neutral	2,88	deleterious	-8,09	deleterious	-6,32	medium_impact	2,55	neutral	0,76	neutral	0,55	neutral	1,26	12,07	0,2	0,45	neutral	0,09	disease	0,51	neutral	0,48	neutral	0,46	1	neutral	0,49	deleterious	0,51	NA	0	neutral	0,38	medium_impact	-0,77	medium_impact	0,3	medium_impact	1,04	0,58	0,8	25,16	10,14	N	0,33	N	0,75	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9122	9122	T	G	MI.1268	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	596	199	L	R	cTg/cGg	0,36	0,02	0	probably_damaging	1	deleterious	0	neutral	4,04	deleterious	-4,11	deleterious	-5,32	high_impact	4,28	damaging	0,46	damaging	0,07	deleterious	4,26	23,9	0,16	0,65	NA	NA	disease	0,88	disease	0,75	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,6	low_impact	-1,4	high_impact	2,57	0,39	0,9	50	8,81	N	0,47	N	0,99	disease_causing	0,83	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4229	4229	C	A	MI.12680	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	923	308	P	H	cCc/cAc	2,79	0,86	0	probably_damaging	0,96	neutral	0,55	neutral	2,77	deleterious	-10,66	deleterious	-7,21	medium_impact	3,18	neutral	0,75	neutral	0,39	deleterious	3,95	23,6	0,1	0,4	neutral	0,23	disease	0,75	disease	0,68	disease	0,69	4	neutral	0,96	neutral	0,3	deleterious	1	deleterious	0,71	low_impact	-2,05	medium_impact	0,32	medium_impact	1,59	0,33	0,8	25,16	10,14	N	0,41	N	0,69	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4229	4229	C	T	MI.12681	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	923	308	P	L	cCc/cTc	2,79	0,86	0	benign	0,11	neutral	0,83	neutral	2,87	deleterious	-7,2	deleterious	-7,87	low_impact	1,51	neutral	0,82	neutral	0,62	deleterious	2,52	19,6	0,16	0,45	neutral	0,13	disease	0,69	neutral	0,35	disease	0,5	0	neutral	0,07	deleterious	0,86	neutral	-6	neutral	0,18	medium_impact	0,1	medium_impact	0,66	medium_impact	0,13	0,52	0,8	25,16	10,14	N	0,32	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4229	4229	C	G	MI.12682	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	923	308	P	R	cCc/cGc	2,79	0,86	0	probably_damaging	0,9	neutral	0,34	neutral	2,81	deleterious	-9,51	deleterious	-7,19	medium_impact	2,98	neutral	0,74	neutral	0,45	deleterious	1,91	15,67	0,09	0,35	neutral	0,12	disease	0,83	disease	0,65	disease	0,72	4	neutral	0,91	neutral	0,22	deleterious	1	deleterious	0,68	low_impact	-1,65	medium_impact	0,11	medium_impact	1,41	0,39	0,8	25,16	10,14	N	0,39	N	0,73	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4231	4231	A	G	MI.12683	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	925	309	I	V	Att/Gtt	-6,19	0	0	benign	0	neutral	0,59	neutral	2,78	neutral	-1,72	neutral	-0,46	low_impact	1,84	neutral	0,87	neutral	0,96	deleterious	0,04	2,93	0,37	0,5	neutral	0,08	neutral	0,18	neutral	0,32	neutral	0,3	4	neutral	0,4	deleterious	0,8	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,36	medium_impact	0,42	0,31	0,8	19,81	12,09	N	0,35	N	0,52	polymorphism	1	0,01	rs878929819	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4231	4231	A	C	MI.12684	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	925	309	I	L	Att/Ctt	-6,19	0	0	benign	0,01	neutral	0,96	neutral	2,79	neutral	-1,86	neutral	-0,99	medium_impact	2,04	neutral	0,76	neutral	0,63	deleterious	0,79	9,38	0,28	0,45	neutral	0,15	neutral	0,29	neutral	0,27	neutral	0,43	1	neutral	0,01	deleterious	0,98	neutral	-3	neutral	0,11	medium_impact	1,12	medium_impact	1,05	medium_impact	0,59	0,53	0,8	19,81	12,09	N	0,33	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4231	4231	A	T	MI.12685	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	925	309	I	F	Att/Ttt	-6,19	0	0	benign	0,16	neutral	0,8	neutral	2,64	deleterious	-3,87	deleterious	-2,72	medium_impact	2,74	neutral	0,83	neutral	0,46	deleterious	2,2	17,52	0,22	0,45	neutral	0,36	disease	0,6	neutral	0,38	neutral	0,49	0	neutral	0,1	deleterious	0,82	neutral	-3	neutral	0,29	medium_impact	-0,08	medium_impact	0,61	medium_impact	1,2	0,45	0,8	19,81	12,09	N	0,22	N	0,81	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4232	4232	T	C	MI.12686	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	926	309	I	T	aTt/aCt	2,33	0,12	0,01	benign	0	neutral	0,43	neutral	2,67	neutral	-1,2	deleterious	-2,56	low_impact	1,84	neutral	0,83	neutral	0,86	deleterious	0,25	5,16	0,17	0,45	neutral	0,22	neutral	0,35	neutral	0,39	neutral	0,44	1	neutral	0,57	deleterious	0,72	neutral	-6	neutral	0,15	high_impact	2,07	medium_impact	0,21	medium_impact	0,42	0,2	0,8	19,81	12,09	N	0,44	N	0,39	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4232	4232	T	A	MI.12687	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	926	309	I	N	aTt/aAt	2,33	0,12	0,01	benign	0,16	neutral	0,45	neutral	2,61	deleterious	-4,97	deleterious	-4,59	medium_impact	3,29	neutral	0,72	neutral	0,44	deleterious	2,54	19,72	0,12	0,4	neutral	0,5	disease	0,67	disease	0,59	disease	0,68	4	neutral	0,46	deleterious	0,65	neutral	-3	neutral	0,33	medium_impact	-0,08	medium_impact	0,23	medium_impact	1,69	0,17	0,8	19,81	12,09	N	0,38	N	0,87	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4232	4232	T	G	MI.12688	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	926	309	I	S	aTt/aGt	2,33	0,12	0,01	benign	0,06	neutral	0,43	neutral	2,65	deleterious	-3,54	deleterious	-3,74	medium_impact	2,74	neutral	0,74	neutral	0,49	deleterious	2,43	18,99	0,05	0,35	neutral	0,34	disease	0,69	disease	0,58	disease	0,64	3	neutral	0,52	deleterious	0,69	neutral	-3	neutral	0,22	medium_impact	0,37	medium_impact	0,21	medium_impact	1,2	0,15	0,8	19,81	12,09	N	0,4	N	0,77	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4233	4233	T	A	MI.12689	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	927	309	I	M	atT/atA	1,41	0,12	0	benign	0,02	neutral	0,32	neutral	2,64	deleterious	-3,37	neutral	-1,59	low_impact	1,94	neutral	0,87	neutral	0,93	deleterious	0,8	9,49	0,35	0,5	neutral	0,33	neutral	0,31	neutral	0,32	neutral	0,47	1	neutral	0,66	deleterious	0,65	neutral	-6	neutral	0,14	medium_impact	0,84	medium_impact	0,09	medium_impact	0,51	0,51	0,8	19,81	12,09	N	0,49	N	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9122	9122	T	C	MI.1269	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	596	199	L	P	cTg/cCg	0,36	0,02	0	probably_damaging	1	deleterious	0	neutral	4,03	deleterious	-4,53	deleterious	-6,24	high_impact	3,94	damaging	0,39	damaging	0,07	deleterious	4,03	23,7	0,17	0,65	NA	NA	disease	0,82	disease	0,74	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,6	low_impact	-1,4	high_impact	2,28	0,56	0,9	50	8,81	N	0,48	N	1	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4233	4233	T	G	MI.12690	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	927	309	I	M	atT/atG	1,41	0,12	0	benign	0,02	neutral	0,32	neutral	2,64	deleterious	-3,37	neutral	-1,59	low_impact	1,94	neutral	0,87	neutral	0,93	deleterious	0,51	7,53	0,35	0,5	neutral	0,33	neutral	0,31	neutral	0,32	neutral	0,47	1	neutral	0,66	deleterious	0,65	neutral	-6	neutral	0,14	medium_impact	0,84	medium_impact	0,09	medium_impact	0,51	0,51	0,8	19,81	12,09	N	0,49	N	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4234	4234	A	T	MI.12691	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	928	310	T	S	Aca/Tca	-6,19	0	0,01	benign	0	neutral	0,43	neutral	2,82	neutral	4,01	neutral	0,32	neutral_impact	-1,38	neutral	0,84	neutral	0,98	neutral	-0,59	0,13	0,34	0,5	neutral	0,11	neutral	0,07	neutral	0,21	neutral	0,29	4	neutral	0,57	deleterious	0,72	neutral	-6	neutral	0,07	high_impact	2,07	medium_impact	0,21	low_impact	-2,39	0,58	0,8	24,84	23,47	N	0,44	N	0,1	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4234	4234	A	G	MI.12692	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	928	310	T	A	Aca/Gca	-6,19	0	0,01	benign	0	neutral	0,54	neutral	2,84	neutral	0,14	neutral	0,59	neutral_impact	-0,5	neutral	0,89	neutral	0,97	neutral	-1,11	0,01	0,25	0,45	neutral	0,09	neutral	0,06	neutral	0,24	neutral	0,19	6	neutral	0,46	deleterious	0,77	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,31	low_impact	-1,63	0,29	0,8	24,84	23,47	N	0,42	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4234	4234	A	C	MI.12693	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	928	310	T	P	Aca/Cca	-6,19	0	0,01	benign	0,09	neutral	0,25	neutral	2,73	neutral	-2,9	neutral	-1,84	medium_impact	2,31	neutral	0,66	neutral	0,4	neutral	1,58	13,76	0,1	0,4	neutral	0,27	disease	0,62	disease	0,59	disease	0,74	5	neutral	0,72	deleterious	0,58	neutral	-3	neutral	0,2	medium_impact	0,19	medium_impact	0,01	medium_impact	0,83	0,43	0,8	24,84	23,47	N	0,41	N	0,25	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4235	4235	C	A	MI.12694	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	929	310	T	K	aCa/aAa	-1,81	0	0	benign	0,03	neutral	0,31	neutral	2,79	neutral	-2,25	neutral	-1,51	medium_impact	2,31	neutral	0,69	neutral	0,51	deleterious	2,45	19,12	0,12	0,4	neutral	0,15	neutral	0,43	disease	0,56	neutral	0,5	0	neutral	0,67	deleterious	0,64	neutral	-3	neutral	0,12	medium_impact	0,67	medium_impact	0,08	medium_impact	0,83	0,4	0,8	24,84	23,47	N	0,44	N	0,32	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4235	4235	C	T	MI.12695	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	929	310	T	M	aCa/aTa	-1,81	0	0	benign	0	neutral	0,32	neutral	2,76	neutral	-1,7	neutral	-0,89	neutral_impact	0,08	neutral	0,87	neutral	0,91	deleterious	0,57	7,97	0,19	0,45	neutral	0,12	neutral	0,17	neutral	0,3	neutral	0,31	4	neutral	0,68	deleterious	0,66	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,09	low_impact	-1,12	0,4	0,8	24,84	23,47	N	0,41	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4237	4237	A	C	MI.12696	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	931	311	I	L	Atc/Ctc	-2,5	0	0	benign	0	neutral	1	neutral	2,9	neutral	0,52	neutral	0,8	neutral_impact	-1,73	neutral	0,83	neutral	0,92	neutral	-0,75	0,06	0,28	0,45	neutral	0,05	neutral	0,05	neutral	0,27	neutral	0,16	7	neutral	0	deleterious	1	neutral	-6	neutral	0,04	high_impact	2,07	high_impact	1,96	low_impact	-2,7	0,57	0,8	19,81	19	N	0,34	N	0,13	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4237	4237	A	T	MI.12697	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	931	311	I	F	Atc/Ttc	-2,5	0	0	benign	0,05	neutral	0,9	neutral	2,75	neutral	-1,8	neutral	-0,18	neutral_impact	-0,57	neutral	0,84	neutral	0,88	deleterious	0,19	4,53	0,18	0,45	neutral	0,12	neutral	0,09	neutral	0,34	neutral	0,28	4	neutral	0,03	deleterious	0,93	neutral	-6	neutral	0,1	medium_impact	0,45	medium_impact	0,81	low_impact	-1,69	0,62	0,8	19,81	19	N	0,29	N	0,43	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4237	4237	A	G	MI.12698	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	931	311	I	V	Atc/Gtc	-2,5	0	0	benign	0,01	neutral	0,59	neutral	2,81	neutral	-0,36	neutral	-0,43	low_impact	0,99	neutral	0,87	neutral	0,75	neutral	1,21	11,82	0,34	0,5	neutral	0,08	neutral	0,08	neutral	0,37	neutral	0,3	4	neutral	0,39	deleterious	0,79	neutral	-6	neutral	0,06	medium_impact	1,12	medium_impact	0,36	medium_impact	-0,32	0,37	0,8	19,81	19	N	0,37	N	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4238	4238	T	A	MI.12699	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	932	311	I	N	aTc/aAc	-3,88	0	0	benign	0,05	neutral	0,32	neutral	2,68	neutral	-2,87	deleterious	-2,89	low_impact	1,45	neutral	0,74	neutral	0,57	deleterious	2,75	21,1	0,14	0,4	neutral	0,31	neutral	0,33	disease	0,62	neutral	0,48	0	neutral	0,65	deleterious	0,64	neutral	-6	neutral	0,18	medium_impact	0,45	medium_impact	0,09	medium_impact	0,08	0,2	0,8	19,81	19	N	0,41	N	0,58	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8585	8585	C	A	MI.127	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	59	20	A	E	gCa/gAa	-1,49	0	0	possibly_damaging	0,6	neutral	0,27	neutral	4,6	neutral	-1,26	neutral	-2,31	low_impact	1,45	neutral	0,93	neutral	0,56	deleterious	3,84	23,4	0,16	0,65	disease	0,69	disease	0,7	disease	0,58	disease	0,73	5	neutral	0,74	neutral	0,34	neutral	-3	deleterious	0,54	medium_impact	-0,92	medium_impact	0,05	medium_impact	0,15	0,59	0,9	24,78	23,03	N	0,35	N	0,71	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9122	9122	T	A	MI.1270	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	596	199	L	Q	cTg/cAg	0,36	0,02	0	probably_damaging	1	deleterious	0	neutral	4,04	deleterious	-4,22	deleterious	-5,32	high_impact	4,28	damaging	0,48	damaging	0,07	deleterious	4,35	24,1	0,19	0,65	NA	NA	disease	0,74	disease	0,63	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,6	low_impact	-1,4	high_impact	2,57	0,5	0,9	50	8,81	N	0,37	N	0,98	disease_causing	0,79	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4238	4238	T	C	MI.12700	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	932	311	I	T	aTc/aCc	-3,88	0	0	benign	0	neutral	0,57	neutral	2,73	neutral	1,18	neutral	-1,32	neutral_impact	-0,74	neutral	0,83	neutral	0,91	deleterious	0,03	2,91	0,19	0,45	neutral	0,11	neutral	0,1	neutral	0,4	neutral	0,31	4	neutral	0,43	deleterious	0,79	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,34	low_impact	-1,83	0,33	0,8	19,81	19	N	0,34	N	0,07	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4238	4238	T	G	MI.12701	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	932	311	I	S	aTc/aGc	-3,88	0	0	benign	0	neutral	0,54	neutral	2,71	neutral	-1,44	neutral	-2,02	neutral_impact	0,48	neutral	0,84	neutral	0,96	deleterious	2,35	18,47	0,09	0,35	neutral	0,19	neutral	0,29	disease	0,52	neutral	0,45	1	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,31	medium_impact	-0,77	0,24	0,8	19,81	19	N	0,3	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4239	4239	C	A	MI.12702	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	933	311	I	M	atC/atA	0,03	0	0	benign	0	neutral	0,27	neutral	2,72	neutral	1,59	neutral	0,6	neutral_impact	-1,27	neutral	0,88	neutral	0,9	deleterious	0,28	5,47	0,33	0,5	neutral	0,12	neutral	0,05	neutral	0,31	neutral	0,25	5	neutral	0,73	deleterious	0,64	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,03	low_impact	-2,3	0,48	0,8	19,81	19	N	0,45	N	0,59	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4239	4239	C	G	MI.12703	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	933	311	I	M	atC/atG	0,03	0	0	benign	0	neutral	0,27	neutral	2,72	neutral	1,59	neutral	0,6	neutral_impact	-1,27	neutral	0,88	neutral	0,9	neutral	-0,13	1,55	0,33	0,5	neutral	0,12	neutral	0,05	neutral	0,31	neutral	0,25	5	neutral	0,73	deleterious	0,64	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,03	low_impact	-2,3	0,48	0,8	19,81	19	N	0,44	N	0,59	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4240	4240	T	A	MI.12704	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	934	312	S	T	Tcc/Acc	-3,19	0	0	benign	0,11	neutral	0,49	neutral	2,78	neutral	-0,77	neutral	-1,22	low_impact	1,12	neutral	0,85	neutral	0,75	deleterious	0,8	9,46	0,34	0,5	neutral	0,09	neutral	0,12	neutral	0,29	neutral	0,29	4	neutral	0,43	deleterious	0,69	neutral	-6	neutral	0,11	medium_impact	0,1	medium_impact	0,27	medium_impact	-0,21	0,41	0,8	13,84	15,43	N	0,37	N	0,37	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4240	4240	T	C	MI.12705	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	934	312	S	P	Tcc/Ccc	-3,19	0	0	benign	0,4	neutral	0,24	neutral	2,72	neutral	-2,58	deleterious	-2,61	medium_impact	3,17	neutral	0,66	neutral	0,33	deleterious	2,12	16,99	0,19	0,45	neutral	0,19	disease	0,54	disease	0,61	disease	0,71	4	neutral	0,72	neutral	0,42	neutral	-3	neutral	0,41	medium_impact	-0,59	medium_impact	-0,01	medium_impact	1,58	0,2	0,8	13,84	15,43	N	0,38	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4240	4240	T	G	MI.12706	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	934	312	S	A	Tcc/Gcc	-3,19	0	0	benign	0	neutral	0,68	neutral	2,83	neutral	0,26	neutral	0,06	neutral_impact	-0,16	neutral	0,88	neutral	0,98	neutral	-0,91	0,03	0,33	0,5	neutral	0,05	neutral	0,03	neutral	0,23	neutral	0,19	6	neutral	0,31	deleterious	0,84	neutral	-6	neutral	0,04	high_impact	2,07	medium_impact	0,46	low_impact	-1,33	0,26	0,8	13,84	15,43	N	0,41	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4241	4241	C	G	MI.12707	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	935	312	S	C	tCc/tGc	-0,43	0	0	benign	0,01	neutral	0,17	neutral	2,7	neutral	-2,52	neutral	-2,06	medium_impact	2,48	neutral	0,92	neutral	0,78	deleterious	1,83	15,16	0,21	0,45	neutral	0,31	neutral	0,3	neutral	0,35	neutral	0,46	1	neutral	0,83	deleterious	0,58	neutral	-3	neutral	0,09	medium_impact	1,12	medium_impact	-0,11	medium_impact	0,98	0,25	0,8	13,84	15,43	N	0,52	P	0,51	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4241	4241	C	T	MI.12708	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	935	312	S	F	tCc/tTc	-0,43	0	0	possibly_damaging	0,67	neutral	0,69	neutral	2,73	neutral	3,78	deleterious	-2,6	neutral_impact	0,5	neutral	0,85	neutral	0,75	neutral	1,34	12,47	0,22	0,45	neutral	0,12	neutral	0,32	neutral	0,34	neutral	0,44	1	neutral	0,6	deleterious	0,51	neutral	-3	neutral	0,42	low_impact	-1,04	medium_impact	0,47	medium_impact	-0,75	0,12	0,8	13,84	15,43	N	0,3	N	1	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4241	4241	C	A	MI.12709	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	935	312	S	Y	tCc/tAc	-0,43	0	0	possibly_damaging	0,67	neutral	1	neutral	2,72	neutral	-0,77	deleterious	-2,8	medium_impact	2,48	neutral	0,81	neutral	0,63	deleterious	2,3	18,19	0,19	0,45	neutral	0,19	neutral	0,35	neutral	0,33	neutral	0,45	1	neutral	0,67	deleterious	0,67	NA	0	deleterious	0,49	low_impact	-1,04	high_impact	1,96	medium_impact	0,98	0,2	0,8	13,84	15,43	N	0,24	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9124	9124	A	C	MI.1271	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	598	200	T	P	Act/Cct	-8,89	0	0	probably_damaging	1	neutral	0,2	neutral	4,23	deleterious	-4,44	deleterious	-5,11	high_impact	3,52	neutral	0,63	neutral	0,47	deleterious	3,59	23,2	0,13	0,65	NA	NA	disease	0,92	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,05	medium_impact	1,92	0,54	0,9	22,12	17,17	N	0,37	N	0,99	polymorphism	0,76	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4243	4243	A	G	MI.12710	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	937	313	S	G	Agc/Ggc	-2,04	0	0	benign	0	neutral	0,36	neutral	2,78	neutral	-1,32	neutral	2,19	neutral_impact	-0,74	neutral	0,84	neutral	0,98	neutral	-0,74	0,06	0,35	0,5	neutral	0,1	neutral	0,02	neutral	0,29	neutral	0,18	6	neutral	0,64	deleterious	0,68	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,14	low_impact	-1,83	0,56	0,8	21,38	23,07	N	0,4	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4243	4243	A	C	MI.12711	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	937	313	S	R	Agc/Cgc	-2,04	0	0	benign	0,18	neutral	0,34	neutral	2,77	neutral	-2,79	neutral	-2,28	medium_impact	2,5	neutral	0,7	neutral	0,41	deleterious	2,31	18,21	0,27	0,45	neutral	0,13	neutral	0,48	disease	0,62	disease	0,58	2	neutral	0,59	deleterious	0,58	neutral	-3	neutral	0,23	medium_impact	-0,13	medium_impact	0,11	medium_impact	1	0,35	0,8	21,38	23,07	N	0,36	N	0,69	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4243	4243	A	T	MI.12712	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	937	313	S	C	Agc/Tgc	-2,04	0	0	benign	0,01	neutral	0,18	neutral	2,7	deleterious	-4,58	neutral	-2,36	medium_impact	2,35	neutral	0,91	neutral	0,93	neutral	0,96	10,42	0,22	0,45	neutral	0,37	neutral	0,29	neutral	0,37	neutral	0,45	1	neutral	0,82	deleterious	0,59	neutral	-3	neutral	0,13	medium_impact	1,12	medium_impact	-0,09	medium_impact	0,86	0,31	0,8	21,38	23,07	N	0,52	P	0,71	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4244	4244	G	A	MI.12713	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	938	313	S	N	aGc/aAc	-0,66	0	0	benign	0	neutral	0,3	neutral	2,75	neutral	-2,47	neutral	-0,63	medium_impact	2,15	neutral	0,93	neutral	0,85	deleterious	0,84	9,7	0,55	0,6	neutral	0,16	neutral	0,25	neutral	0,38	neutral	0,43	1	neutral	0,7	deleterious	0,65	neutral	-3	neutral	0,11	high_impact	2,07	medium_impact	0,07	medium_impact	0,69	0,43	0,8	21,38	23,07	N	0,42	N	0,35	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4244	4244	G	T	MI.12714	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	938	313	S	I	aGc/aTc	-0,66	0	0	benign	0,14	neutral	0,44	neutral	2,76	neutral	-2,2	deleterious	-3,5	low_impact	1,38	neutral	0,75	neutral	0,62	deleterious	2,57	19,94	0,18	0,45	neutral	0,16	neutral	0,39	neutral	0,39	neutral	0,45	1	neutral	0,48	deleterious	0,65	neutral	-6	neutral	0,2	medium_impact	-0,01	medium_impact	0,22	medium_impact	0,02	0,43	0,8	21,38	23,07	N	0,39	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4244	4244	G	C	MI.12715	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	938	313	S	T	aGc/aCc	-0,66	0	0	benign	0	neutral	0,43	neutral	2,78	neutral	-1,9	neutral	-1,71	medium_impact	2,24	neutral	0,78	neutral	0,69	deleterious	1,81	15,05	0,41	0,5	neutral	0,12	neutral	0,15	neutral	0,46	neutral	0,3	4	neutral	0,56	deleterious	0,72	neutral	-3	neutral	0,1	high_impact	2,07	medium_impact	0,21	medium_impact	0,77	0,54	0,8	21,38	23,07	N	0,38	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4246	4246	A	T	MI.12716	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	940	314	I	F	Att/Ttt	-5,5	0	0	possibly_damaging	0,67	neutral	0,93	neutral	2,65	neutral	-1,96	neutral	-1,99	medium_impact	2,15	neutral	0,86	neutral	0,55	deleterious	2,21	17,57	0,18	0,45	neutral	0,23	neutral	0,19	disease	0,54	neutral	0,39	2	neutral	0,64	deleterious	0,63	NA	0	neutral	0,39	low_impact	-1,04	medium_impact	0,9	medium_impact	0,69	0,44	0,8	42,14	8,64	N	0,23	N	0,96	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4246	4246	A	C	MI.12717	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	940	314	I	L	Att/Ctt	-5,5	0	0	benign	0,09	neutral	0,94	neutral	2,85	neutral	2,53	neutral	0,66	neutral_impact	-0,62	neutral	0,8	neutral	0,66	neutral	-0,54	0,17	0,24	0,45	neutral	0,05	neutral	0,02	neutral	0,25	neutral	0,2	6	neutral	0,03	deleterious	0,93	neutral	-6	neutral	0,07	medium_impact	0,19	medium_impact	0,94	low_impact	-1,73	0,42	0,8	42,14	8,64	N	0,32	N	0,61	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4246	4246	A	G	MI.12718	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	940	314	I	V	Att/Gtt	-5,5	0	0	benign	0,01	neutral	0,68	neutral	2,82	neutral	-0,73	neutral	-0,73	low_impact	1,58	neutral	0,89	neutral	0,89	deleterious	0,32	5,9	0,3	0,45	neutral	0,08	neutral	0,05	neutral	0,4	neutral	0,27	5	neutral	0,3	deleterious	0,84	neutral	-6	neutral	0,04	medium_impact	1,12	medium_impact	0,46	medium_impact	0,19	0,34	0,8	42,14	8,64	N	0,43	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4247	4247	T	G	MI.12719	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	941	314	I	S	aTt/aGt	0,26	0	0	benign	0,32	neutral	0,64	neutral	2,67	neutral	-1,77	deleterious	-3,52	low_impact	1,63	neutral	0,74	neutral	0,55	deleterious	2,62	20,3	0,13	0,4	neutral	0,37	neutral	0,25	neutral	0,43	neutral	0,46	1	neutral	0,28	deleterious	0,66	neutral	-6	neutral	0,24	medium_impact	-0,44	medium_impact	0,42	medium_impact	0,24	0,27	0,8	42,14	8,64	N	0,3	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9124	9124	A	T	MI.1272	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	598	200	T	S	Act/Tct	-8,89	0	0	probably_damaging	0,99	neutral	0,41	neutral	4,27	neutral	-1,63	deleterious	-3,36	low_impact	1,56	neutral	0,74	neutral	0,7	deleterious	2,35	18,47	0,44	0,65	NA	NA	disease	0,71	neutral	0,38	disease	0,5	0	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,82	low_impact	-2,65	medium_impact	0,2	medium_impact	0,24	0,63	0,9	22,12	17,17	N	0,32	N	0,88	polymorphism	0,98	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4247	4247	T	A	MI.12720	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	941	314	I	N	aTt/aAt	0,26	0	0	possibly_damaging	0,52	neutral	0,43	neutral	2,63	deleterious	-3,48	deleterious	-4,36	medium_impact	2,58	neutral	0,73	neutral	0,51	deleterious	2,73	21	0,17	0,45	disease	0,52	neutral	0,26	disease	0,63	disease	0,51	0	neutral	0,56	neutral	0,46	NA	0	deleterious	0,44	medium_impact	-0,78	medium_impact	0,21	medium_impact	1,07	0,2	0,8	42,14	8,64	N	0,35	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4247	4247	T	C	MI.12721	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	941	314	I	T	aTt/aCt	0,26	0	0	benign	0,01	neutral	0,43	neutral	2,68	neutral	-0,7	deleterious	-2,61	neutral_impact	0,78	neutral	0,88	neutral	0,71	neutral	1,59	13,8	0,16	0,45	neutral	0,27	neutral	0,09	neutral	0,42	neutral	0,3	4	neutral	0,56	deleterious	0,71	neutral	-6	neutral	0,08	medium_impact	1,12	medium_impact	0,21	medium_impact	-0,51	0,32	0,8	42,14	8,64	N	0,45	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4248	4248	T	A	MI.12722	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	942	314	I	M	atT/atA	3,71	0,37	0,18	possibly_damaging	0,67	neutral	0,38	neutral	2,65	neutral	-2,18	neutral	-0,66	medium_impact	2,58	neutral	0,86	neutral	0,52	deleterious	2,21	17,55	0,32	0,5	neutral	0,2	neutral	0,08	disease	0,61	neutral	0,35	3	neutral	0,7	neutral	0,36	NA	0	neutral	0,4	low_impact	-1,04	medium_impact	0,16	medium_impact	1,07	0,45	0,8	42,14	8,64	N	0,47	N	0,69	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4248	4248	T	G	MI.12723	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	942	314	I	M	atT/atG	3,71	0,37	0,18	possibly_damaging	0,67	neutral	0,38	neutral	2,65	neutral	-2,18	neutral	-0,66	medium_impact	2,58	neutral	0,86	neutral	0,52	deleterious	1,9	15,58	0,32	0,5	neutral	0,2	neutral	0,08	disease	0,61	neutral	0,35	3	neutral	0,7	neutral	0,36	NA	0	neutral	0,4	low_impact	-1,04	medium_impact	0,16	medium_impact	1,07	0,45	0,8	42,14	8,64	N	0,47	N	0,69	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4249	4249	C	G	MI.12724	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	943	315	P	A	Ccc/Gcc	-9,87	0	0	probably_damaging	1	neutral	0,51	neutral	2,64	deleterious	-10,58	deleterious	-6,57	high_impact	4,41	neutral	0,82	damaging	0,23	deleterious	3,29	22,8	0,25	0,45	neutral	0,28	neutral	0,14	disease	0,62	neutral	0,27	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,67	low_impact	-3,57	medium_impact	0,29	high_impact	2,66	0,44	0,8	58,49	10,47	N	0,37	N	0,75	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4249	4249	C	T	MI.12725	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	943	315	P	S	Ccc/Tcc	-9,87	0	0	probably_damaging	1	neutral	0,4	neutral	2,62	deleterious	-10,9	deleterious	-6,6	high_impact	4,07	neutral	0,78	damaging	0,18	deleterious	4,13	23,8	0,3	0,45	neutral	0,31	neutral	0,32	disease	0,6	neutral	0,43	1	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,71	low_impact	-3,57	medium_impact	0,18	high_impact	2,37	0,26	0,8	58,49	10,47	N	0,34	N	0,7	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4249	4249	C	A	MI.12726	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	943	315	P	T	Ccc/Acc	-9,87	0	0	probably_damaging	1	neutral	0,39	neutral	2,59	deleterious	-11,33	deleterious	-6,6	high_impact	4,41	neutral	0,72	damaging	0,15	deleterious	3,93	23,5	0,31	0,45	neutral	0,37	neutral	0,32	disease	0,68	neutral	0,46	1	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,71	low_impact	-3,57	medium_impact	0,17	high_impact	2,66	0,31	0,8	58,49	10,47	N	0,37	N	0,9	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4250	4250	C	T	MI.12727	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	944	315	P	L	cCc/cTc	3,48	0,99	0	probably_damaging	1	neutral	0,65	neutral	2,57	deleterious	-11,84	deleterious	-8,27	high_impact	3,72	neutral	0,77	damaging	0,13	deleterious	4,63	24,5	0,22	0,45	neutral	0,42	neutral	0,31	disease	0,65	neutral	0,44	1	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,72	low_impact	-3,57	medium_impact	0,43	high_impact	2,06	0,54	0,8	58,49	10,47	N	0,48	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4250	4250	C	A	MI.12728	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	944	315	P	H	cCc/cAc	3,48	0,99	0	probably_damaging	1	neutral	0,54	neutral	2,53	deleterious	-12,86	deleterious	-7,45	high_impact	4,41	neutral	0,76	damaging	0,14	deleterious	4,24	23,9	0,22	0,45	disease	0,61	neutral	0,36	disease	0,72	disease	0,6	2	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,75	low_impact	-3,57	medium_impact	0,31	high_impact	2,66	0,26	0,8	58,49	10,47	N	0,51	P	0,69	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4250	4250	C	G	MI.12729	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	944	315	P	R	cCc/cGc	3,48	0,99	0	probably_damaging	1	neutral	0,34	neutral	2,56	deleterious	-11,89	deleterious	-7,45	high_impact	4,41	neutral	0,78	damaging	0,15	deleterious	3,86	23,5	0,2	0,45	neutral	0,44	neutral	0,41	disease	0,74	neutral	0,5	0	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,74	low_impact	-3,57	medium_impact	0,11	high_impact	2,66	0,31	0,8	58,49	10,47	N	0,49	N	0,73	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9124	9124	A	G	MI.1273	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	598	200	T	A	Act/Gct	-8,89	0	0	probably_damaging	0,99	neutral	0,52	neutral	4,37	neutral	-1,75	deleterious	-4,09	medium_impact	3,17	neutral	0,79	neutral	0,61	deleterious	3,61	23,2	0,58	0,7	NA	NA	disease	0,68	disease	0,56	disease	0,58	2	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,8	low_impact	-2,65	medium_impact	0,31	medium_impact	1,62	0,41	0,9	22,12	17,17	N	0,27	N	0,63	polymorphism	0,94	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4252	4252	C	T	MI.12730	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	946	316	P	S	Cct/Tct	-8,95	0	0	probably_damaging	1	neutral	0,41	neutral	2,67	neutral	-0,35	deleterious	-6,66	medium_impact	3,4	damaging	0,53	damaging	0,1	deleterious	4,12	23,8	0,46	0,55	neutral	0,09	neutral	0,3	disease	0,56	neutral	0,43	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,67	low_impact	-3,57	medium_impact	0,19	medium_impact	1,78	0,27	0,8	NA	NA	N	0,34	N	0,7	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4252	4252	C	A	MI.12731	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	946	316	P	T	Cct/Act	-8,95	0	0	probably_damaging	1	neutral	0,4	neutral	2,63	neutral	-0,74	deleterious	-6,66	high_impact	4,04	damaging	0,55	damaging	0,08	deleterious	3,93	23,5	0,37	0,5	neutral	0,14	neutral	0,31	disease	0,52	neutral	0,43	2	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,67	low_impact	-3,57	medium_impact	0,18	high_impact	2,34	0,3	0,8	NA	NA	N	0,34	N	0,9	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4252	4252	C	G	MI.12732	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	946	316	P	A	Cct/Gct	-8,95	0	0	probably_damaging	1	neutral	0,53	neutral	2,68	neutral	-0,07	deleterious	-6,67	high_impact	4,38	damaging	0,57	damaging	0,12	deleterious	3,28	22,8	0,4	0,5	neutral	0,1	neutral	0,15	disease	0,56	neutral	0,32	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,64	low_impact	-3,57	medium_impact	0,3	high_impact	2,64	0,4	0,8	NA	NA	N	0,36	N	0,75	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4253	4253	C	T	MI.12733	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	947	316	P	L	cCt/cTt	5,55	0,94	0	probably_damaging	1	neutral	0,67	neutral	2,62	neutral	-0,66	deleterious	-8,32	high_impact	4,38	damaging	0,6	damaging	0,06	deleterious	4,5	24,3	0,34	0,5	neutral	0,21	neutral	0,3	disease	0,55	neutral	0,43	1	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,68	low_impact	-3,57	medium_impact	0,45	high_impact	2,64	0,68	0,85	NA	NA	P	0,52	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4253	4253	C	A	MI.12734	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	947	316	P	H	cCt/cAt	5,55	0,94	0	probably_damaging	1	neutral	0,54	neutral	2,57	neutral	-2,27	deleterious	-7,5	high_impact	4,38	damaging	0,57	damaging	0,06	deleterious	4,1	23,7	0,3	0,45	neutral	0,34	neutral	0,34	disease	0,62	neutral	0,43	1	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,71	low_impact	-3,57	medium_impact	0,31	high_impact	2,64	0,24	0,8	NA	NA	P	0,51	P	0,69	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4253	4253	C	G	MI.12735	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	947	316	P	R	cCt/cGt	5,55	0,94	0	probably_damaging	1	neutral	0,35	neutral	2,61	neutral	-1,08	deleterious	-7,51	high_impact	4,04	damaging	0,56	damaging	0,07	deleterious	3,79	23,4	0,27	0,45	neutral	0,2	neutral	0,4	disease	0,64	neutral	0,42	2	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,7	low_impact	-3,57	medium_impact	0,12	high_impact	2,34	0,22	0,8	NA	NA	P	0,54	P	0,73	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4255	4255	C	G	MI.12736	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	949	317	Q	E	Caa/Gaa	-14,01	0	0	benign	0,31	neutral	0,3	neutral	2,8	neutral	0,18	neutral	-1,76	medium_impact	3,26	neutral	0,75	damaging	0,14	deleterious	3,07	22,4	0,56	0,6	neutral	0,09	neutral	0,15	neutral	0,48	neutral	0,27	5	neutral	0,64	deleterious	0,5	neutral	-3	neutral	0,36	medium_impact	-0,43	medium_impact	0,07	medium_impact	1,66	0,38	0,8	21,07	21,46	N	0,39	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4255	4255	C	A	MI.12737	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	949	317	Q	K	Caa/Aaa	-14,01	0	0	possibly_damaging	0,51	neutral	0,31	neutral	2,84	neutral	0,37	neutral	-2,12	high_impact	3,6	neutral	0,82	damaging	0,2	deleterious	4	23,6	0,47	0,55	neutral	0,07	neutral	0,19	neutral	0,48	neutral	0,31	4	neutral	0,67	neutral	0,4	deleterious	1	deleterious	0,46	medium_impact	-0,77	medium_impact	0,08	medium_impact	1,96	0,44	0,8	21,07	21,46	N	0,38	N	0,69	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4256	4256	A	C	MI.12738	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	950	317	Q	P	cAa/cCa	3,48	0,96	0	possibly_damaging	0,89	neutral	0,23	neutral	2,72	neutral	-1,47	deleterious	-3,38	medium_impact	3,06	neutral	0,66	damaging	0,12	deleterious	3,47	23	0,15	0,45	neutral	0,23	neutral	0,29	neutral	0,44	neutral	0,4	2	neutral	0,92	neutral	0,17	NA	0	deleterious	0,66	low_impact	-1,6	medium_impact	-0,02	medium_impact	1,48	0,32	0,8	21,07	21,46	N	0,51	P	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4256	4256	A	G	MI.12739	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	950	317	Q	R	cAa/cGa	3,48	0,96	0	possibly_damaging	0,51	neutral	0,36	neutral	2,8	neutral	-0,04	neutral	-2,1	high_impact	3,6	neutral	0,84	damaging	0,18	deleterious	3,55	23,1	0,44	0,55	neutral	0,09	neutral	0,2	neutral	0,4	neutral	0,35	3	neutral	0,62	neutral	0,43	deleterious	1	deleterious	0,47	medium_impact	-0,77	medium_impact	0,14	medium_impact	1,96	0,39	0,8	21,07	21,46	N	0,49	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9125	9125	C	A	MI.1274	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	599	200	T	N	aCt/aAt	5,68	0,98	0	probably_damaging	1	neutral	0,33	neutral	4,24	neutral	-2,49	deleterious	-4,28	medium_impact	3,06	neutral	0,7	neutral	0,54	deleterious	3,66	23,2	0,52	0,65	NA	NA	disease	0,84	disease	0,6	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,12	medium_impact	1,53	0,77	0,9	22,12	17,17	N	0,52	P	0,9	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4256	4256	A	T	MI.12740	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	950	317	Q	L	cAa/cTa	3,48	0,96	0	possibly_damaging	0,71	neutral	0,68	neutral	2,79	neutral	0,44	deleterious	-2,94	low_impact	1,04	neutral	0,88	neutral	0,86	deleterious	2,87	21,7	0,23	0,45	neutral	0,12	neutral	0,17	neutral	0,42	neutral	0,28	4	neutral	0,65	deleterious	0,49	neutral	-3	deleterious	0,49	low_impact	-1,12	medium_impact	0,46	medium_impact	-0,28	0,27	0,8	21,07	21,46	N	0,42	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4257	4257	A	T	MI.12741	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	951	317	Q	H	caA/caT	3,25	0,97	0	benign	0,05	neutral	0,54	neutral	2,73	neutral	-1,35	neutral	-2,14	medium_impact	2,56	neutral	0,88	neutral	0,79	deleterious	2,51	19,5	0,34	0,5	neutral	0,19	neutral	0,08	neutral	0,37	neutral	0,28	4	neutral	0,41	deleterious	0,75	neutral	-3	neutral	0,14	medium_impact	0,45	medium_impact	0,31	medium_impact	1,05	0,3	0,8	21,07	21,46	N	0,51	P	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4257	4257	A	C	MI.12742	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	951	317	Q	H	caA/caC	3,25	0,97	0	benign	0,05	neutral	0,54	neutral	2,73	neutral	-1,35	neutral	-2,14	medium_impact	2,56	neutral	0,88	neutral	0,79	deleterious	2,36	18,54	0,34	0,5	neutral	0,19	neutral	0,08	neutral	0,37	neutral	0,28	4	neutral	0,41	deleterious	0,75	neutral	-3	neutral	0,14	medium_impact	0,45	medium_impact	0,31	medium_impact	1,05	0,3	0,8	21,07	21,46	N	0,5	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4258	4258	A	G	MI.12743	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	952	318	T	A	Acc/Gcc	0,49	0	0	benign	0,11	neutral	0,66	neutral	2,81	neutral	0,26	neutral	-0,9	medium_impact	2,15	neutral	0,81	neutral	0,66	deleterious	3,45	23	0,2	0,45	neutral	0,07	neutral	0,05	neutral	0,44	neutral	0,15	7	neutral	0,23	deleterious	0,78	neutral	-3	neutral	0,19	medium_impact	0,1	medium_impact	0,44	medium_impact	0,69	0,4	0,8	NA	NA	N	0,39	N	0,76	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4258	4258	A	C	MI.12744	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	952	318	T	P	Acc/Ccc	0,49	0	0	possibly_damaging	0,65	neutral	0,32	neutral	2,7	neutral	-1,56	neutral	-1,47	low_impact	1,92	neutral	0,64	neutral	0,44	deleterious	3,51	23,1	0,14	0,4	neutral	0,22	neutral	0,18	disease	0,54	neutral	0,31	4	neutral	0,73	neutral	0,34	neutral	-3	deleterious	0,68	low_impact	-1	medium_impact	0,09	medium_impact	0,49	0,42	0,8	NA	NA	N	0,45	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4258	4258	A	T	MI.12745	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	952	318	T	S	Acc/Tcc	0,49	0	0	benign	0,02	neutral	0,5	neutral	2,78	neutral	-0,07	neutral	-0,88	low_impact	1,23	neutral	0,88	neutral	0,87	deleterious	2,16	17,25	0,27	0,45	neutral	0,07	neutral	0,05	neutral	0,37	neutral	0,13	7	neutral	0,48	deleterious	0,74	neutral	-6	neutral	0,06	medium_impact	0,84	medium_impact	0,28	medium_impact	-0,11	0,51	0,8	NA	NA	N	0,43	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4259	4259	C	T	MI.12746	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	953	318	T	I	aCc/aTc	-0,89	0	0	possibly_damaging	0,65	neutral	0,44	neutral	2,76	neutral	-0,23	neutral	-0,13	low_impact	1,36	neutral	0,77	neutral	0,64	deleterious	4,01	23,6	0,16	0,45	neutral	0,18	neutral	0,16	disease	0,53	neutral	0,28	4	neutral	0,65	neutral	0,4	neutral	-3	deleterious	0,68	low_impact	-1	medium_impact	0,22	medium_impact	0	0,41	0,8	NA	NA	N	0,35	N	0,75	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4259	4259	C	A	MI.12747	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	953	318	T	N	aCc/aAc	-0,89	0	0	benign	0,02	neutral	0,33	neutral	2,72	neutral	-0,96	neutral	-1,51	low_impact	1,02	neutral	0,89	neutral	0,71	deleterious	3,91	23,5	0,31	0,5	neutral	0,16	neutral	0,12	neutral	0,43	neutral	0,19	6	neutral	0,66	deleterious	0,66	neutral	-6	neutral	0,06	medium_impact	0,84	medium_impact	0,1	medium_impact	-0,3	0,42	0,8	NA	NA	N	0,5	N	0,81	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4259	4259	C	G	MI.12748	MT-ND1	I	ENSG00000198888	ENSP00000354687	ENST00000361390	NU1M_HUMAN	P03886	4535	YP_003024026.1	953	318	T	S	aCc/aGc	-0,89	0	0	benign	0,02	neutral	0,5	neutral	2,78	neutral	-0,07	neutral	-0,88	low_impact	1,23	neutral	0,88	neutral	0,87	deleterious	2,48	19,31	0,27	0,45	neutral	0,07	neutral	0,05	neutral	0,37	neutral	0,13	7	neutral	0,48	deleterious	0,74	neutral	-6	neutral	0,06	medium_impact	0,84	medium_impact	0,28	medium_impact	-0,11	0,51	0,8	NA	NA	N	0,41	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4470	4470	A	C	MI.12749	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1	1	M	L	Atg/Ctg	6,94	1	0	possibly_damaging	0,75	deleterious	0	NA	NA	neutral	1,04	NA	NA	NA	NA	neutral	0,78	neutral	0,46	neutral	1,55	13,61	0,11	0,4	NA	NA	neutral	0,28	disease	0,56	neutral	0,38	2	deleterious	1	neutral	0,13	deleterious	3	deleterious	NA	NA	NA	NA	NA	NA	NA	0,2	0,8	NA	NA	P	0,6	P	0,62	NA	NA	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9125	9125	C	G	MI.1275	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	599	200	T	S	aCt/aGt	5,68	0,98	0	probably_damaging	0,99	neutral	0,41	neutral	4,27	neutral	-1,63	deleterious	-3,36	low_impact	1,56	neutral	0,74	neutral	0,7	deleterious	2,54	19,75	0,44	0,65	NA	NA	disease	0,71	neutral	0,38	disease	0,5	0	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,82	low_impact	-2,65	medium_impact	0,2	medium_impact	0,24	0,63	0,9	22,12	17,17	N	0,49	N	0,88	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4470	4470	A	T	MI.12750	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1	1	M	L	Atg/Ttg	6,94	1	0	possibly_damaging	0,75	deleterious	0	NA	NA	neutral	1,04	NA	NA	NA	NA	neutral	0,78	neutral	0,46	neutral	1,51	13,39	0,11	0,4	NA	NA	neutral	0,28	disease	0,56	neutral	0,38	2	deleterious	1	neutral	0,13	deleterious	3	deleterious	NA	NA	NA	NA	NA	NA	NA	0,2	0,8	NA	NA	P	0,6	P	0,62	NA	NA	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4470	4470	A	G	MI.12751	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1	1	M	V	Atg/Gtg	6,94	1	0	possibly_damaging	0,83	deleterious	0	NA	NA	neutral	0,48	NA	NA	NA	NA	neutral	0,74	neutral	0,49	deleterious	0,83	9,65	0,16	0,45	NA	NA	neutral	0,35	disease	0,59	neutral	0,37	3	deleterious	1	neutral	0,09	deleterious	3	neutral	0,21	NA	NA	NA	NA	NA	NA	0,18	0,8	NA	NA	P	0,58	P	0,73	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4471	4471	T	A	MI.12752	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	2	1	M	K	aTg/aAg	3,48	1	0	probably_damaging	0,92	deleterious	0	NA	NA	neutral	-0,67	NA	NA	NA	NA	neutral	0,8	neutral	0,41	deleterious	2,33	18,35	0,08	0,35	NA	NA	neutral	0,49	disease	0,62	disease	0,55	1	deleterious	1	neutral	0,04	deleterious	4	deleterious	NA	NA	NA	NA	NA	NA	NA	0,07	0,8	NA	NA	N	0,44	N	0,93	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4471	4471	T	C	MI.12753	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	2	1	M	T	aTg/aCg	3,48	1	0	probably_damaging	0,92	deleterious	0	NA	NA	neutral	-0,72	NA	NA	NA	NA	neutral	0,77	neutral	0,48	neutral	1,22	11,88	0,09	0,35	NA	NA	neutral	0,48	disease	0,59	neutral	0,48	0	deleterious	1	neutral	0,04	deleterious	4	neutral	0,3	NA	NA	NA	NA	NA	NA	0,06	0,8	NA	NA	N	0,42	N	0,78	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4472	4472	T	G	MI.12754	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	3	1	M	I	atT/atG	3,71	1	0	possibly_damaging	0,88	deleterious	0	NA	NA	neutral	0,37	NA	NA	NA	NA	neutral	0,86	neutral	0,77	NA	NA	NA	0,11	0,4	NA	NA	neutral	0,32	neutral	0,42	neutral	0,18	6	deleterious	1	neutral	0,06	deleterious	3	deleterious	NA	NA	NA	NA	NA	NA	NA	0,29	0,8	NA	NA	P	0,49	N	0,05	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4472	4472	T	C	MI.12755	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	3	1	M	I	atT/atC	-1,81	0	0	possibly_damaging	0,88	deleterious	0	NA	NA	neutral	0,37	NA	NA	NA	NA	neutral	0,86	neutral	0,77	NA	NA	NA	0,11	0,4	NA	NA	neutral	0,32	neutral	0,42	neutral	0,18	6	deleterious	1	neutral	0,06	deleterious	3	deleterious	NA	NA	NA	NA	NA	NA	NA	0,29	0,8	NA	NA	N	0,39	N	0,05	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4473	4473	A	C	MI.12756	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	4	2	N	H	Aat/Cat	-1,81	0	0	probably_damaging	1	neutral	0,53	neutral	4,06	neutral	-1,98	deleterious	-4,12	medium_impact	2,93	neutral	0,86	damaging	0,12	deleterious	2,81	21,4	0,6	0,65	NA	NA	neutral	0,33	neutral	0,39	neutral	0,19	6	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	0,24	medium_impact	1,32	0,14	0,8	0,86	6,99	N	0,25	N	0,54	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4473	4473	A	G	MI.12757	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	4	2	N	D	Aat/Gat	-1,81	0	0	probably_damaging	1	neutral	0,2	neutral	4,15	neutral	-0,36	deleterious	-4,12	medium_impact	3,07	neutral	0,84	damaging	0,13	deleterious	3,56	23,1	0,8	0,85	NA	NA	neutral	0,3	disease	0,53	neutral	0,35	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,7	low_impact	-3,54	medium_impact	-0,13	medium_impact	1,44	0,39	0,8	0,86	6,99	N	0,41	N	0,74	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4473	4473	A	T	MI.12758	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	4	2	N	Y	Aat/Tat	-1,81	0	0	probably_damaging	1	neutral	1	neutral	4,05	neutral	-1,98	deleterious	-6,49	medium_impact	2,82	neutral	0,88	damaging	0,13	deleterious	3,43	23	0,24	0,45	NA	NA	neutral	0,45	disease	0,53	neutral	0,39	2	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,73	low_impact	-3,54	high_impact	1,87	medium_impact	1,23	0,16	0,8	0,86	6,99	N	0,25	N	0,9	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4474	4474	A	C	MI.12759	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	5	2	N	T	aAt/aCt	2,79	0,02	0	probably_damaging	1	neutral	0,43	neutral	4,12	neutral	-0,46	deleterious	-4,88	medium_impact	2,34	neutral	0,87	neutral	0,32	deleterious	3,12	22,6	0,55	0,6	NA	NA	neutral	0,34	neutral	0,33	neutral	0,19	6	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,71	low_impact	-3,54	medium_impact	0,14	medium_impact	0,83	0,25	0,8	0,86	6,99	N	0,38	N	0,65	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9125	9125	C	T	MI.1276	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	599	200	T	I	aCt/aTt	5,68	0,98	0	probably_damaging	1	neutral	0,47	neutral	4,38	neutral	-1,8	deleterious	-4,65	low_impact	1,94	neutral	0,87	neutral	0,78	deleterious	3,98	23,6	0,47	0,65	NA	NA	disease	0,9	neutral	0,41	disease	0,53	1	deleterious	0,99	neutral	0,24	neutral	-2	deleterious	0,85	low_impact	-3,6	medium_impact	0,26	medium_impact	0,57	0,58	0,9	22,12	17,17	N	0,48	N	0,97	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4474	4474	A	G	MI.12760	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	5	2	N	S	aAt/aGt	2,79	0,02	0	probably_damaging	1	neutral	0,46	neutral	4,17	neutral	0,09	deleterious	-4,01	low_impact	1,64	neutral	0,89	neutral	0,86	neutral	1,51	13,39	0,77	0,8	NA	NA	neutral	0,1	neutral	0,18	neutral	0,26	5	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,68	low_impact	-3,54	medium_impact	0,17	medium_impact	0,24	0,32	0,8	0,86	6,99	N	0,44	N	0,38	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4474	4474	A	T	MI.12761	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	5	2	N	I	aAt/aTt	2,79	0,02	0	probably_damaging	1	neutral	0,4	neutral	4,07	neutral	-1,34	deleterious	-7,33	medium_impact	2,42	neutral	0,88	damaging	0,22	deleterious	3,65	23,2	0,22	0,45	NA	NA	disease	0,52	neutral	0,5	neutral	0,5	0	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,11	medium_impact	0,89	0,16	0,8	0,86	6,99	N	0,38	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4475	4475	T	G	MI.12762	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	6	2	N	K	aaT/aaG	0,72	0	0	probably_damaging	1	neutral	0,33	neutral	4,14	neutral	-0,27	deleterious	-4,3	low_impact	1,1	neutral	0,92	neutral	0,85	deleterious	2,51	19,53	0,65	0,7	NA	NA	neutral	0,3	neutral	0,39	neutral	0,17	7	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	0,04	medium_impact	-0,22	0,5	0,8	0,86	6,99	N	0,49	N	0,51	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4475	4475	T	A	MI.12763	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	6	2	N	K	aaT/aaA	0,72	0	0	probably_damaging	1	neutral	0,33	neutral	4,14	neutral	-0,27	deleterious	-4,3	low_impact	1,1	neutral	0,92	neutral	0,85	deleterious	2,82	21,5	0,65	0,7	NA	NA	neutral	0,3	neutral	0,39	neutral	0,17	7	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	0,04	medium_impact	-0,22	0,5	0,8	0,86	6,99	N	0,49	N	0,51	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4476	4476	C	T	MI.12764	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	7	3	P	S	Ccc/Tcc	-4,35	0	0	probably_damaging	1	neutral	0,7	neutral	4,1	neutral	-0,48	deleterious	-6,87	medium_impact	2,52	neutral	0,86	neutral	0,57	deleterious	3,63	23,2	0,46	0,55	NA	NA	neutral	0,49	neutral	0,5	neutral	0,37	3	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,41	medium_impact	0,98	0,28	0,8	0,86	9,39	N	0,25	N	0,62	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4476	4476	C	A	MI.12765	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	7	3	P	T	Ccc/Acc	-4,35	0	0	probably_damaging	1	neutral	0,59	neutral	4,07	neutral	-0,88	deleterious	-6,86	medium_impact	2,56	neutral	0,92	neutral	0,45	deleterious	3,64	23,2	0,38	0,5	NA	NA	disease	0,51	neutral	0,39	neutral	0,5	0	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,3	medium_impact	1,01	0,58	0,8	0,86	9,39	N	0,29	N	0,79	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4476	4476	C	G	MI.12766	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	7	3	P	A	Ccc/Gcc	-4,35	0	0	probably_damaging	1	neutral	0,77	neutral	4,12	neutral	-0,25	deleterious	-6,87	medium_impact	3,25	neutral	0,88	neutral	0,57	deleterious	2,88	21,8	0,44	0,55	NA	NA	neutral	0,28	disease	0,51	neutral	0,25	5	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0,5	medium_impact	1,59	0,65	0,8	0,86	9,39	N	0,33	N	0,6	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4477	4477	C	A	MI.12767	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	8	3	P	H	cCc/cAc	3,48	0,93	0	probably_damaging	1	neutral	0,57	neutral	4,01	neutral	-2,44	deleterious	-7,63	medium_impact	3,25	neutral	0,88	neutral	0,4	deleterious	3,79	23,4	0,25	0,45	NA	NA	disease	0,52	disease	0,59	disease	0,64	3	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	0,28	medium_impact	1,59	0,3	0,8	0,86	9,39	N	0,41	N	0,86	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4477	4477	C	T	MI.12768	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	8	3	P	L	cCc/cTc	3,48	0,93	0	probably_damaging	1	neutral	0,8	neutral	4,05	neutral	-0,89	deleterious	-8,39	medium_impact	2,5	neutral	0,93	neutral	0,47	deleterious	4,18	23,8	0,32	0,5	NA	NA	neutral	0,5	disease	0,51	disease	0,51	0	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,54	medium_impact	0,96	0,71	0,85	0,86	9,39	N	0,39	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4477	4477	C	G	MI.12769	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	8	3	P	R	cCc/cGc	3,48	0,93	0	probably_damaging	1	neutral	0,54	neutral	4,05	neutral	-1,2	deleterious	-7,63	medium_impact	3,13	neutral	0,86	neutral	0,41	deleterious	3,44	23	0,21	0,45	NA	NA	disease	0,58	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,25	medium_impact	1,49	0,37	0,8	0,86	9,39	N	0,34	N	0,9	polymorphism	1	0,09	rs28430764	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9127	9127	A	T	MI.1277	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	601	201	I	F	Atc/Ttc	-9,36	0	0	benign	0,12	neutral	0,13	neutral	4,19	neutral	-0,17	deleterious	-2,79	low_impact	1,72	neutral	0,83	neutral	0,44	neutral	1,12	11,3	0,45	0,65	NA	NA	disease	0,74	neutral	0,41	disease	0,52	0	neutral	0,85	deleterious	0,51	neutral	-6	neutral	0,29	medium_impact	0,07	medium_impact	-0,18	medium_impact	0,38	0,67	0,9	14,6	19,22	N	0,35	N	0,84	polymorphism	0,86	0,07	rs199732761	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4479	4479	C	G	MI.12770	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	10	4	L	V	Ctg/Gtg	-5,04	0	0	probably_damaging	0,95	neutral	0,43	neutral	4,22	neutral	-0,23	neutral	-1,32	medium_impact	2,46	neutral	0,92	neutral	0,87	deleterious	2,15	17,17	0,42	0,55	NA	NA	neutral	0,14	neutral	0,34	neutral	0,24	5	neutral	0,95	neutral	0,24	deleterious	1	deleterious	0,63	low_impact	-1,97	medium_impact	0,14	medium_impact	0,93	0,43	0,8	3,17	7,69	N	0,41	N	0,36	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4479	4479	C	A	MI.12771	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	10	4	L	M	Ctg/Atg	-5,04	0	0	probably_damaging	0,99	neutral	0,26	neutral	4,15	neutral	-1,46	neutral	-0,94	low_impact	1,26	neutral	0,94	neutral	0,87	deleterious	2,24	17,76	0,35	0,5	NA	NA	neutral	0,07	neutral	0,17	neutral	0,24	5	deleterious	0,99	neutral	0,14	neutral	-2	deleterious	0,65	low_impact	-2,62	medium_impact	-0,04	medium_impact	-0,08	0,5	0,8	3,17	7,69	P	0,58	P	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4480	4480	T	A	MI.12772	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	11	4	L	Q	cTg/cAg	-4,11	0	0	probably_damaging	0,99	neutral	0,25	neutral	4,17	neutral	-1,13	deleterious	-4,16	low_impact	1,71	neutral	0,85	neutral	0,7	deleterious	2,9	21,8	0,14	0,4	NA	NA	neutral	0,09	neutral	0,26	neutral	0,21	6	deleterious	0,99	neutral	0,13	neutral	-2	deleterious	0,67	low_impact	-2,62	medium_impact	-0,06	medium_impact	0,3	0,19	0,8	3,17	7,69	N	0,44	N	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4480	4480	T	C	MI.12773	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	11	4	L	P	cTg/cCg	-4,11	0	0	benign	0,32	neutral	0,2	neutral	4,12	neutral	-2,36	deleterious	-4,41	low_impact	1,23	neutral	0,92	neutral	0,84	deleterious	2,31	18,26	0,09	0,35	NA	NA	neutral	0,45	disease	0,56	neutral	0,36	3	neutral	0,76	neutral	0,44	neutral	-6	neutral	0,35	medium_impact	-0,5	medium_impact	-0,13	medium_impact	-0,11	0,25	0,8	3,17	7,69	N	0,46	N	0,47	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4480	4480	T	G	MI.12774	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	11	4	L	R	cTg/cGg	-4,11	0	0	probably_damaging	0,99	neutral	0,31	neutral	4,16	neutral	-1,11	deleterious	-4,3	medium_impact	2,61	neutral	0,86	neutral	0,51	deleterious	3,96	23,6	0,1	0,4	NA	NA	neutral	0,49	neutral	0,49	neutral	0,38	3	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,75	low_impact	-2,62	medium_impact	0,02	medium_impact	1,05	0,17	0,8	3,17	7,69	N	0,37	N	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4482	4482	G	C	MI.12775	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	13	5	A	P	Gcc/Ccc	-6,19	0	0	possibly_damaging	0,83	neutral	0,25	neutral	4,1	neutral	-2,28	neutral	-2,41	low_impact	1,32	neutral	0,87	neutral	0,39	deleterious	3,65	23,2	0,13	0,4	NA	NA	disease	0,69	neutral	0,4	disease	0,51	0	neutral	0,88	neutral	0,21	neutral	-3	deleterious	0,79	low_impact	-1,43	medium_impact	-0,06	medium_impact	-0,03	0,43	0,8	10,37	8,87	N	0,37	N	0,77	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4482	4482	G	A	MI.12776	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	13	5	A	T	Gcc/Acc	-6,19	0	0	possibly_damaging	0,62	neutral	0,43	neutral	4,18	neutral	-0,58	neutral	-0,4	neutral_impact	-0,14	neutral	0,86	neutral	0,93	deleterious	2,05	16,52	0,24	0,45	NA	NA	neutral	0,2	neutral	0,16	neutral	0,22	6	neutral	0,63	neutral	0,41	neutral	-3	deleterious	0,67	medium_impact	-0,99	medium_impact	0,14	low_impact	-1,26	0,64	0,8	10,37	8,87	N	0,43	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4482	4482	G	T	MI.12777	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	13	5	A	S	Gcc/Tcc	-6,19	0	0	benign	0,33	neutral	0,62	neutral	4,18	neutral	-0,46	neutral	-1,36	neutral_impact	0,04	neutral	0,88	neutral	0,66	deleterious	3,51	23,1	0,33	0,5	NA	NA	neutral	0,4	neutral	0,2	neutral	0,22	6	neutral	0,3	deleterious	0,65	neutral	-6	deleterious	0,74	medium_impact	-0,52	medium_impact	0,33	low_impact	-1,11	0,38	0,8	10,37	8,87	N	0,33	N	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4483	4483	C	A	MI.12778	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	14	5	A	D	gCc/gAc	-1,12	0	0	possibly_damaging	0,72	neutral	0,18	neutral	4,12	neutral	-1,46	deleterious	-2,86	medium_impact	2,13	neutral	0,87	neutral	0,41	deleterious	4,38	24,1	0,13	0,4	NA	NA	disease	0,66	disease	0,67	disease	0,71	4	neutral	0,86	neutral	0,23	NA	0	deleterious	0,75	low_impact	-1,17	medium_impact	-0,16	medium_impact	0,65	0,26	0,8	10,37	8,87	N	0,39	N	0,74	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4483	4483	C	G	MI.12779	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	14	5	A	G	gCc/gGc	-1,12	0	0	benign	0	neutral	0,35	neutral	4,12	neutral	-1,47	deleterious	-2,84	low_impact	1,58	neutral	0,91	neutral	0,58	deleterious	3,83	23,4	0,3	0,45	NA	NA	neutral	0,37	neutral	0,49	neutral	0,2	6	neutral	0,65	deleterious	0,68	neutral	-6	deleterious	0,69	medium_impact	1,95	medium_impact	0,06	medium_impact	0,19	0,58	0,8	10,37	8,87	N	0,42	N	0,43	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9127	9127	A	C	MI.1278	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	601	201	I	L	Atc/Ctc	-9,36	0	0	benign	0,01	neutral	1	neutral	4,32	neutral	1,11	neutral	-0,73	neutral_impact	-0,22	neutral	0,88	neutral	0,73	neutral	-0,36	0,48	0,39	0,65	NA	NA	neutral	0,2	neutral	0,26	neutral	0,19	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,13	medium_impact	1,14	high_impact	1,98	low_impact	-1,29	0,58	0,9	14,6	19,22	N	0,3	N	0,66	polymorphism	1	0,02	rs199732761	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4483	4483	C	T	MI.12780	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	14	5	A	V	gCc/gTc	-1,12	0	0	possibly_damaging	0,62	neutral	0,68	neutral	4,22	neutral	-0,07	neutral	1,27	neutral_impact	-0,15	neutral	0,86	neutral	0,94	deleterious	2,36	18,55	0,19	0,45	NA	NA	neutral	0,23	neutral	0,16	neutral	0,21	6	neutral	0,54	deleterious	0,53	neutral	-3	deleterious	0,68	medium_impact	-0,99	medium_impact	0,39	low_impact	-1,27	0,7	0,85	10,37	8,87	N	0,35	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4485	4485	C	G	MI.12781	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	16	6	Q	E	Caa/Gaa	-6,65	0	0	possibly_damaging	0,56	neutral	0,26	neutral	4,26	neutral	0,36	neutral	-0,73	low_impact	1,42	neutral	0,89	damaging	0,26	deleterious	2,86	21,7	0,36	0,5	NA	NA	neutral	0,28	disease	0,53	neutral	0,34	3	neutral	0,73	neutral	0,35	neutral	-3	deleterious	0,47	medium_impact	-0,89	medium_impact	-0,04	medium_impact	0,05	0,48	0,8	14,7	10,55	N	0,43	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4485	4485	C	A	MI.12782	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	16	6	Q	K	Caa/Aaa	-6,65	0	0	possibly_damaging	0,74	neutral	0,35	neutral	4,29	neutral	0,63	neutral	-0,4	neutral_impact	-0,88	neutral	0,84	neutral	0,46	deleterious	2,75	21,1	0,34	0,5	NA	NA	neutral	0,09	neutral	0,26	neutral	0,2	6	neutral	0,77	neutral	0,31	neutral	-3	deleterious	0,53	low_impact	-1,21	medium_impact	0,06	low_impact	-1,89	0,29	0,8	14,7	10,55	N	0,37	N	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4486	4486	A	C	MI.12783	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	17	6	Q	P	cAa/cCa	-3,42	0	0	probably_damaging	0,94	neutral	0,26	neutral	4,19	neutral	-1,56	neutral	-1,27	neutral_impact	0,26	neutral	0,71	damaging	0,21	deleterious	3,17	22,7	0,06	0,35	NA	NA	disease	0,61	disease	0,66	disease	0,72	4	neutral	0,95	neutral	0,16	neutral	-2	deleterious	0,73	low_impact	-1,89	medium_impact	-0,04	medium_impact	-0,93	0,32	0,8	14,7	10,55	N	0,27	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4486	4486	A	G	MI.12784	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	17	6	Q	R	cAa/cGa	-3,42	0	0	possibly_damaging	0,74	neutral	0,33	neutral	4,23	neutral	0,09	neutral	-0,57	neutral_impact	0,72	neutral	0,85	damaging	0,23	deleterious	3,38	22,9	0,24	0,45	NA	NA	neutral	0,36	neutral	0,47	neutral	0,16	7	neutral	0,78	neutral	0,3	neutral	-3	deleterious	0,59	low_impact	-1,21	medium_impact	0,04	medium_impact	-0,54	0,12	0,8	14,7	10,55	N	0,33	N	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4486	4486	A	T	MI.12785	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	17	6	Q	L	cAa/cTa	-3,42	0	0	possibly_damaging	0,59	neutral	0,92	neutral	4,3	neutral	0,22	neutral	1,38	neutral_impact	-1,15	neutral	0,9	neutral	0,95	neutral	1,04	10,91	0,13	0,4	NA	NA	neutral	0,12	neutral	0,13	neutral	0,18	6	neutral	0,54	deleterious	0,67	neutral	-3	deleterious	0,46	medium_impact	-0,94	medium_impact	0,8	low_impact	-2,11	0,08	0,8	14,7	10,55	N	0,32	N	0,38	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4487	4487	A	T	MI.12786	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	18	6	Q	H	caA/caT	-2,04	0	0	benign	0,04	neutral	0,54	neutral	4,19	neutral	-1,2	neutral	-0,27	neutral_impact	0,72	neutral	0,88	neutral	0,53	deleterious	2,91	21,9	0,3	0,45	NA	NA	neutral	0,18	neutral	0,45	neutral	0,19	6	neutral	0,41	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	0,47	medium_impact	0,25	medium_impact	-0,54	0,58	0,8	14,7	10,55	N	0,34	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4487	4487	A	C	MI.12787	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	18	6	Q	H	caA/caC	-2,04	0	0	benign	0,04	neutral	0,54	neutral	4,19	neutral	-1,2	neutral	-0,27	neutral_impact	0,72	neutral	0,88	neutral	0,53	deleterious	2,76	21,1	0,3	0,45	NA	NA	neutral	0,18	neutral	0,45	neutral	0,19	6	neutral	0,41	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	0,47	medium_impact	0,25	medium_impact	-0,54	0,58	0,8	14,7	10,55	N	0,34	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4488	4488	C	A	MI.12788	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	19	7	P	T	Ccc/Acc	-11,71	0	0	possibly_damaging	0,53	neutral	0,43	neutral	4,27	neutral	0,27	neutral	1,9	neutral_impact	-1,05	neutral	0,87	neutral	0,96	deleterious	2,1	16,84	0,16	0,45	disease	0,73	neutral	0,06	neutral	0,16	neutral	0,41	2	neutral	0,57	neutral	0,45	neutral	-3	deleterious	0,47	medium_impact	-0,84	medium_impact	0,14	low_impact	-2,03	0,65	0,8	5,19	7,52	N	0,45	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4488	4488	C	T	MI.12789	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	19	7	P	S	Ccc/Tcc	-11,71	0	0	possibly_damaging	0,61	neutral	0,52	neutral	4,27	neutral	0,41	neutral	1,36	neutral_impact	-1,06	neutral	0,78	neutral	0,97	deleterious	2,11	16,89	0,22	0,45	disease	0,67	neutral	0,06	neutral	0,15	neutral	0,41	2	neutral	0,58	neutral	0,46	neutral	-3	deleterious	0,49	medium_impact	-0,98	medium_impact	0,23	low_impact	-2,04	0,2	0,8	5,19	7,52	N	0,42	N	0,61	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9127	9127	A	G	MI.1279	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	601	201	I	V	Atc/Gtc	-9,36	0	0	benign	0	neutral	0,33	neutral	4,3	neutral	0,25	neutral	-0,64	low_impact	1,51	neutral	0,95	neutral	0,94	deleterious	0,12	3,84	0,67	0,75	NA	NA	neutral	0,32	neutral	0,38	neutral	0,17	7	neutral	0,67	deleterious	0,67	neutral	-6	neutral	0,16	high_impact	2,09	medium_impact	0,12	medium_impact	0,2	0,52	0,9	14,6	19,22	N	0,35	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4488	4488	C	G	MI.12790	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	19	7	P	A	Ccc/Gcc	-11,71	0	0	benign	0,34	neutral	0,55	neutral	4,29	neutral	0,68	neutral	1,16	neutral_impact	-0,56	neutral	0,87	neutral	0,82	neutral	1,18	11,64	0,17	0,45	disease	0,67	neutral	0,06	neutral	0,19	neutral	0,39	2	neutral	0,37	deleterious	0,61	neutral	-6	neutral	0,36	medium_impact	-0,53	medium_impact	0,26	low_impact	-1,62	0,7	0,85	5,19	7,52	N	0,41	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4489	4489	C	G	MI.12791	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	20	7	P	R	cCc/cGc	-4,11	0	0	possibly_damaging	0,81	neutral	0,34	neutral	4,22	neutral	-0,16	neutral	0,01	low_impact	1,1	neutral	0,9	neutral	0,41	deleterious	2	16,23	0,1	0,4	disease	0,64	neutral	0,29	disease	0,52	disease	0,6	2	neutral	0,83	neutral	0,27	neutral	-3	deleterious	0,63	low_impact	-1,37	medium_impact	0,05	medium_impact	-0,22	0,41	0,8	5,19	7,52	N	0,5	N	0,91	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4489	4489	C	A	MI.12792	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	20	7	P	H	cCc/cAc	-4,11	0	0	probably_damaging	0,93	neutral	0,53	neutral	4,19	neutral	-1,2	neutral	-0,42	neutral_impact	0,55	neutral	0,88	neutral	0,45	deleterious	2,17	17,32	0,11	0,4	disease	0,82	neutral	0,15	neutral	0,45	neutral	0,4	2	neutral	0,92	neutral	0,3	neutral	-2	deleterious	0,66	low_impact	-1,83	medium_impact	0,24	medium_impact	-0,68	0,24	0,8	5,19	7,52	N	0,33	N	0,9	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4489	4489	C	T	MI.12793	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	20	7	P	L	cCc/cTc	-4,11	0	0	benign	0,01	neutral	0,79	neutral	4,31	neutral	0,26	neutral	2,13	neutral_impact	-1,95	neutral	0,95	neutral	0,94	deleterious	2,13	17,02	0,13	0,4	disease	0,81	neutral	0,08	neutral	0,21	neutral	0,38	2	neutral	0,18	deleterious	0,89	neutral	-6	neutral	0,17	medium_impact	1,03	medium_impact	0,53	low_impact	-2,79	0,7	0,85	5,19	7,52	N	0,26	N	0,71	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4491	4491	G	A	MI.12794	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	22	8	V	I	Gtc/Atc	-4,11	0	0,03	benign	0	neutral	1	neutral	4,27	neutral	-0,22	neutral	0,07	neutral_impact	-1,42	neutral	0,89	neutral	0,96	neutral	-1,27	0,01	0,42	0,55	neutral	0,24	neutral	0,03	neutral	0,14	neutral	0,22	6	neutral	0	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,95	high_impact	1,87	low_impact	-2,34	0,86	0,9	2,59	7,91	N	0,31	N	0,02	polymorphism	1	0,01	rs201172504	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4491	4491	G	C	MI.12795	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	22	8	V	L	Gtc/Ctc	-4,11	0	0,03	benign	0,02	neutral	0,81	neutral	4,24	neutral	-0,34	neutral	-0,37	neutral_impact	-1,48	neutral	0,87	neutral	0,92	deleterious	-0,01	2,45	0,21	0,45	neutral	0,22	neutral	0,34	neutral	0,22	neutral	0,44	1	neutral	0,15	deleterious	0,9	neutral	-6	neutral	0,13	medium_impact	0,75	medium_impact	0,56	low_impact	-2,39	0,5	0,8	2,59	7,91	N	0,27	N	0,21	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4491	4491	G	T	MI.12796	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	22	8	V	F	Gtc/Ttc	-4,11	0	0,03	benign	0,2	neutral	0,75	neutral	4,11	neutral	-1,92	neutral	-2,08	neutral_impact	0,07	neutral	0,91	neutral	0,79	neutral	1,61	13,93	0,04	0,35	neutral	0,27	disease	0,71	neutral	0,24	disease	0,51	0	neutral	0,15	deleterious	0,78	neutral	-6	neutral	0,27	medium_impact	-0,25	medium_impact	0,47	low_impact	-1,09	0,31	0,8	2,59	7,91	N	0,25	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4492	4492	T	A	MI.12797	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	23	8	V	D	gTc/gAc	0,26	0	0	possibly_damaging	0,44	neutral	0,06	neutral	4,05	deleterious	-3,18	deleterious	-4,07	low_impact	1,83	neutral	0,85	neutral	0,44	deleterious	2,3	18,2	0,02	0,35	neutral	0,3	disease	0,72	disease	0,69	disease	0,74	5	neutral	0,93	neutral	0,31	neutral	-3	neutral	0,36	medium_impact	-0,7	medium_impact	-0,46	medium_impact	0,4	0,13	0,8	2,59	7,91	N	0,35	N	0,51	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4492	4492	T	C	MI.12798	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	23	8	V	A	gTc/gCc	0,26	0	0	benign	0,08	neutral	0,17	neutral	4,15	neutral	-1	neutral	-1,97	low_impact	0,86	neutral	0,9	neutral	0,93	deleterious	0,29	5,57	0,11	0,4	neutral	0,29	neutral	0,27	neutral	0,32	neutral	0,44	1	neutral	0,81	deleterious	0,55	neutral	-6	neutral	0,15	medium_impact	0,17	medium_impact	-0,17	medium_impact	-0,42	0,19	0,8	2,59	7,91	P	0,55	P	0,33	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4492	4492	T	G	MI.12799	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	23	8	V	G	gTc/gGc	0,26	0	0	benign	0,33	neutral	0,19	neutral	4,07	neutral	-2,88	deleterious	-4,38	low_impact	1,49	neutral	0,88	neutral	0,49	neutral	1,68	14,28	0,03	0,35	disease	0,51	disease	0,55	disease	0,57	disease	0,7	4	neutral	0,77	neutral	0,43	neutral	-6	neutral	0,25	medium_impact	-0,52	medium_impact	-0,14	medium_impact	0,11	0,17	0,8	2,59	7,91	N	0,39	N	0,49	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8585	8585	C	T	MI.128	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	59	20	A	V	gCa/gTa	-1,49	0	0	benign	0,28	neutral	0,51	neutral	4,67	neutral	-0,42	neutral	1,65	neutral_impact	-0,64	neutral	0,87	neutral	0,95	deleterious	0,55	7,79	0,37	0,65	neutral	0,27	neutral	0,3	neutral	0,32	neutral	0,44	1	neutral	0,39	deleterious	0,62	neutral	-6	neutral	0,31	medium_impact	-0,37	medium_impact	0,3	low_impact	-1,65	0,57	0,9	24,78	23,03	N	0,28	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9128	9128	T	A	MI.1280	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	602	201	I	N	aTc/aAc	-0,1	0	0,01	benign	0,12	deleterious	0	neutral	4,14	neutral	-2,93	deleterious	-5,13	medium_impact	3,29	neutral	0,84	neutral	0,41	deleterious	2,72	20,9	0,35	0,65	NA	NA	disease	0,76	disease	0,61	disease	0,71	4	deleterious	1	neutral	0,44	deleterious	1	neutral	0,34	medium_impact	0,07	low_impact	-1,4	medium_impact	1,72	0,54	0,9	14,6	19,22	N	0,34	N	0,99	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4494	4494	A	C	MI.12800	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	25	9	I	L	Atc/Ctc	-5,04	0	0	benign	0,03	neutral	1	neutral	4,35	neutral	0,94	neutral	-1,38	neutral_impact	-0,02	neutral	0,84	neutral	0,95	deleterious	2,11	16,9	0,18	0,45	neutral	0,17	neutral	0,21	neutral	0,19	neutral	0,37	3	neutral	0,03	deleterious	0,99	neutral	-6	deleterious	0,62	medium_impact	0,59	high_impact	1,87	low_impact	-1,16	0,51	0,8	0,58	7,5	N	0,34	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4494	4494	A	T	MI.12801	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	25	9	I	F	Atc/Ttc	-5,04	0	0	benign	0,4	neutral	0,46	neutral	4,17	neutral	-1,31	deleterious	-3,39	neutral_impact	0,46	neutral	0,83	neutral	0,63	deleterious	3,45	23	0,14	0,4	disease	0,52	neutral	0,33	neutral	0,24	neutral	0,39	2	neutral	0,48	deleterious	0,53	neutral	-6	deleterious	0,7	medium_impact	-0,64	medium_impact	0,17	medium_impact	-0,76	0,44	0,8	0,58	7,5	N	0,3	N	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4494	4494	A	G	MI.12802	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	25	9	I	V	Atc/Gtc	-5,04	0	0	benign	0,08	neutral	0,2	neutral	4,22	neutral	-0,12	neutral	-0,88	medium_impact	2,02	neutral	0,88	neutral	0,92	neutral	1,5	13,31	0,31	0,45	neutral	0,34	neutral	0,3	neutral	0,26	neutral	0,48	0	neutral	0,78	deleterious	0,56	neutral	-3	deleterious	0,64	medium_impact	0,17	medium_impact	-0,13	medium_impact	0,56	0,36	0,8	0,58	7,5	P	0,51	P	0,3	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4495	4495	T	G	MI.12803	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	26	9	I	S	aTc/aGc	-0,2	0	0	benign	0,37	neutral	0,11	neutral	4,12	neutral	-1,88	deleterious	-5,22	low_impact	1,7	neutral	0,82	neutral	0,59	deleterious	4,03	23,6	0,02	0,35	disease	0,51	disease	0,6	disease	0,6	disease	0,52	0	neutral	0,87	neutral	0,37	neutral	-6	deleterious	0,76	medium_impact	-0,59	medium_impact	-0,3	medium_impact	0,29	0,2	0,8	0,58	7,5	N	0,37	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4495	4495	T	C	MI.12804	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	26	9	I	T	aTc/aCc	-0,2	0	0	benign	0,29	neutral	0,1	neutral	4,14	neutral	-1,51	deleterious	-4,28	medium_impact	2,14	neutral	0,89	neutral	0,84	deleterious	3,06	22,4	0,06	0,35	neutral	0,47	neutral	0,5	neutral	0,45	neutral	0,49	0	neutral	0,88	neutral	0,41	neutral	-3	deleterious	0,73	medium_impact	-0,44	medium_impact	-0,32	medium_impact	0,66	0,17	0,8	0,58	7,5	N	0,52	P	0,92	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4495	4495	T	A	MI.12805	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	26	9	I	N	aTc/aAc	-0,2	0	0	possibly_damaging	0,71	neutral	0,16	neutral	4,08	deleterious	-3	deleterious	-6,13	medium_impact	2,56	neutral	0,88	neutral	0,41	deleterious	4,2	23,9	0,05	0,35	disease	0,68	disease	0,74	disease	0,6	disease	0,71	4	neutral	0,87	neutral	0,23	NA	0	deleterious	0,8	low_impact	-1,15	medium_impact	-0,19	medium_impact	1,01	0,11	0,8	0,58	7,5	N	0,4	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4496	4496	C	G	MI.12806	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	27	9	I	M	atC/atG	1,87	0,02	0	benign	0,04	neutral	0,27	neutral	4,14	neutral	-1,02	neutral	-2,38	low_impact	0,86	neutral	0,91	neutral	0,79	deleterious	1,99	16,17	0,17	0,45	disease	0,53	neutral	0,34	neutral	0,2	neutral	0,43	1	neutral	0,71	deleterious	0,62	neutral	-6	deleterious	0,69	medium_impact	0,47	medium_impact	-0,03	medium_impact	-0,42	0,46	0,8	0,58	7,5	N	0,44	N	0,66	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4496	4496	C	A	MI.12807	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	27	9	I	M	atC/atA	1,87	0,02	0	benign	0,04	neutral	0,27	neutral	4,14	neutral	-1,02	neutral	-2,38	low_impact	0,86	neutral	0,91	neutral	0,79	deleterious	2,43	19,04	0,17	0,45	disease	0,53	neutral	0,34	neutral	0,2	neutral	0,43	1	neutral	0,71	deleterious	0,62	neutral	-6	deleterious	0,69	medium_impact	0,47	medium_impact	-0,03	medium_impact	-0,42	0,46	0,8	0,58	7,5	N	0,44	N	0,66	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4497	4497	T	G	MI.12808	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	28	10	Y	D	Tac/Gac	-12,17	0	0	possibly_damaging	0,83	deleterious	0,02	neutral	4,14	deleterious	-3,36	deleterious	-3,04	low_impact	1,56	neutral	0,85	damaging	0,19	deleterious	3,64	23,2	0,03	0,35	disease	0,7	disease	0,59	disease	0,65	disease	0,71	4	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,66	low_impact	-1,43	medium_impact	-0,73	medium_impact	0,17	0,24	0,8	4,03	8,73	N	0,33	N	0,85	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4497	4497	T	C	MI.12809	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	28	10	Y	H	Tac/Cac	-12,17	0	0	probably_damaging	0,96	neutral	0,06	neutral	4,15	neutral	-2,6	neutral	-1,79	medium_impact	2,11	neutral	0,85	damaging	0,2	deleterious	2,22	17,63	0,13	0,4	disease	0,62	neutral	0,38	disease	0,61	disease	0,59	2	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,7	low_impact	-2,06	medium_impact	-0,46	medium_impact	0,63	0,26	0,8	4,03	8,73	N	0,26	N	0,61	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9128	9128	T	C	MI.1281	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	602	201	I	T	aTc/aCc	-0,1	0	0,01	benign	0	neutral	0,12	neutral	4,21	neutral	-1,15	deleterious	-3,3	low_impact	1,27	neutral	0,96	neutral	0,66	deleterious	0,4	6,58	0,52	0,65	NA	NA	neutral	0,42	neutral	0,4	neutral	0,19	6	neutral	0,88	deleterious	0,56	neutral	-6	neutral	0,16	high_impact	2,09	medium_impact	-0,2	medium_impact	-0,01	0,57	0,9	14,6	19,22	N	0,36	N	0,95	polymorphism	1	0,07	rs878867946	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4497	4497	T	A	MI.12810	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	28	10	Y	N	Tac/Aac	-12,17	0	0	possibly_damaging	0,78	neutral	0,05	neutral	4,15	neutral	-2,67	neutral	-2,24	medium_impact	2,11	neutral	0,84	damaging	0,25	deleterious	3,69	23,3	0,05	0,35	disease	0,58	neutral	0,46	disease	0,55	disease	0,6	2	neutral	0,97	neutral	0,14	NA	0	deleterious	0,57	low_impact	-1,3	medium_impact	-0,5	medium_impact	0,63	0,31	0,8	4,03	8,73	N	0,36	N	0,74	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4498	4498	A	G	MI.12811	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	29	10	Y	C	tAc/tGc	-5,5	0	0	probably_damaging	0,97	deleterious	0,02	neutral	4,14	deleterious	-3,08	neutral	-1,54	medium_impact	2,11	neutral	0,87	damaging	0,2	deleterious	3,27	22,8	0,04	0,35	disease	0,6	disease	0,63	neutral	0,43	neutral	0,47	1	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,7	low_impact	-2,18	medium_impact	-0,73	medium_impact	0,63	0,13	0,8	4,03	8,73	N	0,35	N	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4498	4498	A	C	MI.12812	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	29	10	Y	S	tAc/tCc	-5,5	0	0	benign	0,12	neutral	0,3	neutral	4,19	neutral	-1,55	neutral	-1,38	neutral_impact	0,06	neutral	0,83	neutral	0,96	neutral	1,61	13,93	0,06	0,35	neutral	0,37	neutral	0,29	neutral	0,33	neutral	0,43	1	neutral	0,65	deleterious	0,59	neutral	-6	neutral	0,18	medium_impact	-0,01	medium_impact	0	low_impact	-1,09	0,31	0,8	4,03	8,73	N	0,42	N	0,48	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4498	4498	A	T	MI.12813	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	29	10	Y	F	tAc/tTc	-5,5	0	0	possibly_damaging	0,67	neutral	0,78	neutral	4,3	neutral	0,2	neutral	-0,19	neutral_impact	0,23	neutral	0,91	neutral	0,87	deleterious	1,84	15,2	0,31	0,45	neutral	0,3	neutral	0,37	neutral	0,23	neutral	0,45	1	neutral	0,61	deleterious	0,56	neutral	-3	deleterious	0,5	low_impact	-1,08	medium_impact	0,51	medium_impact	-0,95	0,63	0,8	4,03	8,73	N	0,37	N	0,51	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4500	4500	T	G	MI.12814	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	31	11	S	A	Tct/Gct	-2,73	0	0,01	benign	0,14	neutral	0,18	neutral	4,23	neutral	0,54	neutral	-0,15	low_impact	1,91	neutral	0,85	neutral	0,91	neutral	-0,11	1,65	0,25	0,45	neutral	0,27	neutral	0,3	neutral	0,4	neutral	0,44	1	neutral	0,79	deleterious	0,52	neutral	-6	neutral	0,15	medium_impact	-0,08	medium_impact	-0,16	medium_impact	0,46	0,46	0,8	1,15	8,59	N	0,46	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4500	4500	T	C	MI.12815	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	31	11	S	P	Tct/Cct	-2,73	0	0,01	benign	0,01	neutral	0,09	neutral	4,11	neutral	-2,21	neutral	-1,64	medium_impact	2,35	neutral	0,92	neutral	0,5	deleterious	0,68	8,68	0,04	0,35	disease	0,58	disease	0,83	disease	0,56	disease	0,75	5	neutral	0,91	deleterious	0,54	neutral	-3	neutral	0,28	medium_impact	1,03	medium_impact	-0,35	medium_impact	0,83	0,26	0,8	1,15	8,59	N	0,38	N	0,06	polymorphism	1	0,04	rs879007369	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4500	4500	T	A	MI.12816	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	31	11	S	T	Tct/Act	-2,73	0	0,01	benign	0,01	neutral	0,37	neutral	4,2	neutral	-0,56	neutral	0,06	neutral_impact	0,4	neutral	0,97	neutral	0,98	neutral	-0,52	0,19	0,33	0,5	neutral	0,25	neutral	0,25	neutral	0,2	neutral	0,44	1	neutral	0,62	deleterious	0,68	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,08	medium_impact	-0,81	0,59	0,8	1,15	8,59	N	0,51	P	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4501	4501	C	A	MI.12817	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	32	11	S	Y	tCt/tAt	-7,34	0	0	benign	0,31	neutral	0,36	neutral	4,12	neutral	-1,86	neutral	-0,67	medium_impact	2,35	neutral	0,9	neutral	0,73	deleterious	0,28	5,53	0,03	0,35	neutral	0,45	disease	0,72	neutral	0,34	disease	0,51	0	neutral	0,57	deleterious	0,53	neutral	-3	neutral	0,32	medium_impact	-0,48	medium_impact	0,07	medium_impact	0,83	0,25	0,8	1,15	8,59	N	0,37	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4501	4501	C	G	MI.12818	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	32	11	S	C	tCt/tGt	-7,34	0	0	possibly_damaging	0,85	neutral	0,07	neutral	4,11	neutral	-2,64	neutral	-1,05	medium_impact	2,11	neutral	0,8	neutral	0,37	deleterious	1,88	15,47	0,05	0,35	disease	0,58	disease	0,7	neutral	0,43	neutral	0,49	0	neutral	0,96	neutral	0,11	NA	0	deleterious	0,63	low_impact	-1,49	medium_impact	-0,42	medium_impact	0,63	0,22	0,8	1,15	8,59	N	0,36	N	0,34	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4501	4501	C	T	MI.12819	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	32	11	S	F	tCt/tTt	-7,34	0	0	benign	0,01	neutral	1	neutral	4,16	neutral	-0,98	neutral	0,08	low_impact	0,98	neutral	0,95	neutral	0,96	neutral	-0,28	0,72	0,06	0,35	neutral	0,25	disease	0,61	neutral	0,28	neutral	0,45	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,15	medium_impact	1,03	high_impact	1,87	medium_impact	-0,32	0,15	0,8	1,15	8,59	N	0,28	N	0,14	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9128	9128	T	G	MI.1282	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	602	201	I	S	aTc/aGc	-0,1	0	0,01	benign	0,04	deleterious	0	neutral	4,2	neutral	-1,49	deleterious	-4,21	medium_impact	2,04	neutral	0,81	neutral	0,44	deleterious	2,47	19,25	0,35	0,65	NA	NA	disease	0,73	disease	0,51	disease	0,53	1	deleterious	1	deleterious	0,48	deleterious	1	neutral	0,24	medium_impact	0,55	low_impact	-1,4	medium_impact	0,65	0,56	0,9	14,6	19,22	N	0,35	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4503	4503	A	T	MI.12820	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	34	12	T	S	Acc/Tcc	-3,65	0	0	possibly_damaging	0,72	neutral	0,46	neutral	4,2	neutral	-0,86	deleterious	-3,61	low_impact	0,91	neutral	0,83	neutral	0,79	deleterious	0,07	3,26	0,35	0,5	neutral	0,24	neutral	0,07	neutral	0,16	neutral	0,27	5	neutral	0,71	neutral	0,37	neutral	-3	deleterious	0,5	low_impact	-1,17	medium_impact	0,17	medium_impact	-0,38	0,66	0,8	2,59	7,45	N	0,45	N	0,41	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4503	4503	A	G	MI.12821	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	34	12	T	A	Acc/Gcc	-3,65	0	0	benign	0,11	neutral	0,51	neutral	4,16	neutral	-0,69	deleterious	-4,51	medium_impact	2,02	neutral	0,94	neutral	0,6	neutral	1,79	14,94	0,24	0,45	neutral	0,48	disease	0,57	disease	0,56	disease	0,66	3	neutral	0,41	deleterious	0,7	neutral	-3	neutral	0,23	medium_impact	0,03	medium_impact	0,22	medium_impact	0,56	0,29	0,8	2,59	7,45	N	0,31	N	0,75	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4503	4503	A	C	MI.12822	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	34	12	T	P	Acc/Ccc	-3,65	0	0	probably_damaging	0,95	neutral	0,2	neutral	4,07	deleterious	-3,07	deleterious	-5,42	medium_impact	3,02	neutral	0,75	neutral	0,37	deleterious	2,12	16,96	0,05	0,35	disease	0,74	disease	0,92	disease	0,68	disease	0,79	6	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,84	low_impact	-1,97	medium_impact	-0,13	medium_impact	1,4	0,35	0,8	2,59	7,45	N	0,29	N	0,94	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4504	4504	C	A	MI.12823	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	35	12	T	N	aCc/aAc	4,4	0,99	0	probably_damaging	0,95	neutral	0,31	neutral	4,09	neutral	-2,05	deleterious	-4,52	medium_impact	2	neutral	0,85	neutral	0,57	neutral	1,74	14,62	0,24	0,45	disease	0,55	disease	0,85	neutral	0,42	disease	0,71	4	neutral	0,96	neutral	0,18	deleterious	1	deleterious	0,76	low_impact	-1,97	medium_impact	0,02	medium_impact	0,54	0,58	0,8	2,59	7,45	N	0,52	P	0,83	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4504	4504	C	T	MI.12824	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	35	12	T	I	aCc/aTc	4,4	0,99	0	probably_damaging	0,91	neutral	0,41	neutral	4,17	neutral	-0,53	deleterious	-5,37	low_impact	1,92	neutral	0,88	neutral	0,55	deleterious	1,96	15,93	0,13	0,4	disease	0,59	disease	0,82	disease	0,55	disease	0,75	5	neutral	0,91	neutral	0,25	neutral	-2	deleterious	0,73	low_impact	-1,72	medium_impact	0,12	medium_impact	0,47	0,62	0,8	2,59	7,45	P	0,54	P	0,83	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4504	4504	C	G	MI.12825	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	35	12	T	S	aCc/aGc	4,4	0,99	0	possibly_damaging	0,72	neutral	0,46	neutral	4,2	neutral	-0,86	deleterious	-3,61	low_impact	0,91	neutral	0,83	neutral	0,79	neutral	-0,26	0,8	0,35	0,5	neutral	0,24	neutral	0,07	neutral	0,16	neutral	0,27	5	neutral	0,71	neutral	0,37	neutral	-3	deleterious	0,5	low_impact	-1,17	medium_impact	0,17	medium_impact	-0,38	0,66	0,8	2,59	7,45	P	0,55	P	0,41	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4506	4506	A	G	MI.12826	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	37	13	I	V	Atc/Gtc	-3,88	0	0	benign	0,01	neutral	0,28	neutral	4,21	neutral	-0,04	neutral	-0,22	neutral_impact	0,62	neutral	0,98	neutral	0,97	neutral	-0,7	0,07	0,56	0,6	neutral	0,38	neutral	0,31	neutral	0,35	neutral	0,45	1	neutral	0,71	deleterious	0,64	neutral	-6	neutral	0,15	medium_impact	1,03	medium_impact	-0,02	medium_impact	-0,62	0,38	0,8	0,29	9,03	N	0,45	N	0,65	polymorphism	1	0,01	rs11510099	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4506	4506	A	C	MI.12827	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	37	13	I	L	Atc/Ctc	-3,88	0	0	benign	0,08	neutral	1	neutral	4,46	neutral	1,12	neutral	-0,32	neutral_impact	-0,9	neutral	0,88	neutral	0,93	neutral	-1,03	0,01	0,24	0,45	neutral	0,22	neutral	0,16	neutral	0,27	neutral	0,24	5	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,14	medium_impact	0,17	high_impact	1,87	low_impact	-1,9	0,55	0,8	0,29	9,03	N	0,3	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4506	4506	A	T	MI.12828	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	37	13	I	F	Atc/Ttc	-3,88	0	0	possibly_damaging	0,58	neutral	0,27	neutral	4,13	neutral	-1,1	deleterious	-2,68	medium_impact	2,02	neutral	0,86	neutral	0,5	deleterious	2,02	16,36	0,22	0,45	disease	0,59	disease	0,8	disease	0,65	disease	0,78	6	neutral	0,73	neutral	0,35	NA	0	deleterious	0,63	medium_impact	-0,93	medium_impact	-0,03	medium_impact	0,56	0,55	0,8	0,29	9,03	N	0,34	N	0,57	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4507	4507	T	G	MI.12829	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	38	13	I	S	aTc/aGc	-3,42	0	0	possibly_damaging	0,65	neutral	0,35	neutral	4,11	neutral	-1,44	deleterious	-4,03	medium_impact	2,12	neutral	0,88	neutral	0,49	deleterious	2,3	18,17	0,04	0,35	disease	0,52	disease	0,78	disease	0,6	disease	0,77	5	neutral	0,71	neutral	0,35	NA	0	deleterious	0,59	low_impact	-1,04	medium_impact	0,06	medium_impact	0,64	0,2	0,8	0,29	9,03	N	0,33	N	0,86	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9129	9129	C	G	MI.1283	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	603	201	I	M	atC/atG	3,83	0,4	0	benign	0,01	neutral	0,42	neutral	4,21	neutral	-0,59	neutral	-1,25	low_impact	1,09	neutral	0,88	neutral	0,92	deleterious	0,42	6,77	0,55	0,65	NA	NA	neutral	0,39	neutral	0,34	neutral	0,17	7	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,16	medium_impact	1,14	medium_impact	0,21	medium_impact	-0,16	0,76	0,9	14,6	19,22	N	0,36	N	0,28	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4507	4507	T	A	MI.12830	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	38	13	I	N	aTc/aAc	-3,42	0	0	possibly_damaging	0,85	deleterious	0,04	neutral	4,07	neutral	-2,91	deleterious	-4,97	medium_impact	2,27	neutral	0,87	neutral	0,43	deleterious	3,87	23,5	0,08	0,35	disease	0,75	disease	0,85	disease	0,63	disease	0,8	6	neutral	0,98	neutral	0,1	deleterious	4	deleterious	0,75	low_impact	-1,49	medium_impact	-0,56	medium_impact	0,77	0,19	0,8	0,29	9,03	N	0,41	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4507	4507	T	C	MI.12831	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	38	13	I	T	aTc/aCc	-3,42	0	0	benign	0,36	neutral	0,27	neutral	4,12	neutral	-1,21	deleterious	-3	low_impact	1,66	neutral	0,91	neutral	0,66	neutral	1,29	12,24	0,13	0,4	neutral	0,38	disease	0,54	disease	0,58	disease	0,7	4	neutral	0,68	neutral	0,46	neutral	-6	neutral	0,42	medium_impact	-0,57	medium_impact	-0,03	medium_impact	0,25	0,28	0,8	0,29	9,03	N	0,39	N	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4508	4508	C	G	MI.12832	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	39	13	I	M	atC/atG	5,78	0,87	0	benign	0,05	neutral	0,32	neutral	4,16	neutral	-1,18	neutral	-0,71	neutral_impact	0,16	neutral	0,95	neutral	0,91	deleterious	0,11	3,73	0,35	0,5	disease	0,59	neutral	0,49	neutral	0,31	disease	0,56	1	neutral	0,65	deleterious	0,64	neutral	-6	neutral	0,23	medium_impact	0,37	medium_impact	0,03	low_impact	-1,01	0,52	0,8	0,29	9,03	N	0,43	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4508	4508	C	A	MI.12833	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	39	13	I	M	atC/atA	5,78	0,87	0	benign	0,05	neutral	0,32	neutral	4,16	neutral	-1,18	neutral	-0,71	neutral_impact	0,16	neutral	0,95	neutral	0,91	deleterious	0,54	7,75	0,35	0,5	disease	0,59	neutral	0,49	neutral	0,31	disease	0,56	1	neutral	0,65	deleterious	0,64	neutral	-6	neutral	0,23	medium_impact	0,37	medium_impact	0,03	low_impact	-1,01	0,52	0,8	0,29	9,03	N	0,43	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4509	4509	T	A	MI.12834	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	40	14	F	I	Ttt/Att	-2,73	0	0	benign	0	neutral	0,57	neutral	4,23	neutral	0,05	neutral	0,75	neutral_impact	-0,88	neutral	0,97	neutral	0,98	neutral	1,38	12,68	0,15	0,4	neutral	0,19	neutral	0,14	neutral	0,27	neutral	0,26	5	neutral	0,42	deleterious	0,79	neutral	-6	neutral	0,09	medium_impact	1,95	medium_impact	0,28	low_impact	-1,89	0,56	0,8	4,9	7,47	N	0,34	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4509	4509	T	G	MI.12835	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	40	14	F	V	Ttt/Gtt	-2,73	0	0	benign	0,03	neutral	0,55	neutral	4,23	neutral	0,11	neutral	0,27	neutral_impact	0,23	neutral	0,91	neutral	0,94	deleterious	2,36	18,57	0,13	0,4	neutral	0,22	neutral	0,42	neutral	0,43	neutral	0,43	1	neutral	0,41	deleterious	0,76	neutral	-6	neutral	0,12	medium_impact	0,59	medium_impact	0,26	medium_impact	-0,95	0,29	0,8	4,9	7,47	N	0,31	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4509	4509	T	C	MI.12836	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	40	14	F	L	Ttt/Ctt	-2,73	0	0	benign	0	neutral	1	neutral	4,3	neutral	0,56	neutral	0,32	neutral_impact	0,3	neutral	0,98	neutral	0,96	neutral	1,61	13,89	0,2	0,45	neutral	0,23	neutral	0,18	neutral	0,29	neutral	0,25	5	neutral	0	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,95	high_impact	1,87	medium_impact	-0,89	0,53	0,8	4,9	7,47	N	0,29	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4510	4510	T	C	MI.12837	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	41	14	F	S	tTt/tCt	-2,73	0	0	benign	0,21	neutral	0,31	neutral	4,12	neutral	-1,27	neutral	-2,21	low_impact	1,12	neutral	0,85	neutral	0,63	deleterious	3,98	23,6	0,06	0,35	neutral	0,43	neutral	0,34	neutral	0,42	neutral	0,45	1	neutral	0,63	deleterious	0,55	neutral	-6	neutral	0,3	medium_impact	-0,27	medium_impact	0,02	medium_impact	-0,2	0,23	0,8	4,9	7,47	N	0,36	N	0,48	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4510	4510	T	A	MI.12838	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	41	14	F	Y	tTt/tAt	-2,73	0	0	possibly_damaging	0,47	neutral	0,56	neutral	4,09	neutral	-2,1	neutral	-1,14	medium_impact	2,44	neutral	0,91	neutral	0,55	deleterious	3,91	23,5	0,23	0,45	disease	0,51	neutral	0,33	neutral	0,42	neutral	0,33	3	neutral	0,44	deleterious	0,55	NA	0	deleterious	0,48	medium_impact	-0,75	medium_impact	0,27	medium_impact	0,91	0,57	0,8	4,9	7,47	N	0,41	N	0,33	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4510	4510	T	G	MI.12839	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	41	14	F	C	tTt/tGt	-2,73	0	0	possibly_damaging	0,77	neutral	0,11	neutral	4,07	neutral	-2,83	neutral	-1,93	low_impact	1,9	neutral	0,83	neutral	0,42	deleterious	3,87	23,5	0,09	0,35	disease	0,63	disease	0,6	neutral	0,41	neutral	0,48	0	neutral	0,92	neutral	0,17	neutral	-3	deleterious	0,6	low_impact	-1,28	medium_impact	-0,3	medium_impact	0,46	0,15	0,8	4,9	7,47	N	0,36	N	0,48	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9129	9129	C	A	MI.1284	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	603	201	I	M	atC/atA	3,83	0,4	0	benign	0,01	neutral	0,42	neutral	4,21	neutral	-0,59	neutral	-1,25	low_impact	1,09	neutral	0,88	neutral	0,92	neutral	0,89	10,01	0,55	0,65	NA	NA	neutral	0,39	neutral	0,34	neutral	0,17	7	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,16	medium_impact	1,14	medium_impact	0,21	medium_impact	-0,16	0,76	0,9	14,6	19,22	N	0,36	N	0,28	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4511	4511	T	G	MI.12840	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	42	14	F	L	ttT/ttG	1,41	0	0	benign	0	neutral	1	neutral	4,3	neutral	0,56	neutral	0,32	neutral_impact	0,3	neutral	0,98	neutral	0,96	deleterious	1,91	15,64	0,2	0,45	neutral	0,23	neutral	0,18	neutral	0,29	neutral	0,25	5	neutral	0	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,95	high_impact	1,87	medium_impact	-0,89	0,53	0,8	4,9	7,47	N	0,34	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4511	4511	T	A	MI.12841	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	42	14	F	L	ttT/ttA	1,41	0	0	benign	0	neutral	1	neutral	4,3	neutral	0,56	neutral	0,32	neutral_impact	0,3	neutral	0,98	neutral	0,96	deleterious	2,04	16,46	0,2	0,45	neutral	0,23	neutral	0,18	neutral	0,29	neutral	0,25	5	neutral	0	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,95	high_impact	1,87	medium_impact	-0,89	0,53	0,8	4,9	7,47	N	0,35	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4512	4512	G	C	MI.12842	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	43	15	A	P	Gca/Cca	-14,94	0	0	possibly_damaging	0,65	deleterious	0,04	neutral	4,05	deleterious	-4,1	neutral	-1,73	low_impact	0,9	neutral	0,78	neutral	0,36	deleterious	3,24	22,8	0,06	0,35	disease	0,74	disease	0,81	disease	0,72	disease	0,79	6	neutral	0,96	neutral	0,2	deleterious	1	deleterious	0,64	low_impact	-1,04	medium_impact	-0,56	medium_impact	-0,39	0,54	0,8	2,31	7,56	N	0,29	N	0,23	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4512	4512	G	T	MI.12843	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	43	15	A	S	Gca/Tca	-14,94	0	0	benign	0,2	neutral	0,25	neutral	4,11	neutral	-2,1	neutral	0,27	neutral_impact	-1,38	neutral	0,79	neutral	0,96	neutral	-0,09	1,8	0,23	0,45	neutral	0,27	neutral	0,32	neutral	0,31	neutral	0,45	1	neutral	0,7	deleterious	0,53	neutral	-6	neutral	0,24	medium_impact	-0,25	medium_impact	-0,06	low_impact	-2,31	0,5	0,8	2,31	7,56	N	0,39	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4512	4512	G	A	MI.12844	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	43	15	A	T	Gca/Aca	-14,94	0	0	benign	0,01	neutral	0,18	neutral	4,14	neutral	-1,52	neutral	0,15	neutral_impact	-0,7	neutral	0,95	neutral	0,97	deleterious	0,63	8,38	0,21	0,45	neutral	0,41	neutral	0,19	neutral	0,28	neutral	0,36	3	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	-0,16	low_impact	-1,73	0,7	0,85	2,31	7,56	N	0,5	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4513	4513	C	T	MI.12845	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	44	15	A	V	gCa/gTa	-8,72	0	0	benign	0,2	neutral	0,14	neutral	4,18	neutral	-0,89	neutral	0,14	neutral_impact	-0,08	neutral	0,86	neutral	0,82	neutral	1,12	11,34	0,18	0,45	neutral	0,4	neutral	0,48	neutral	0,37	neutral	0,47	1	neutral	0,84	deleterious	0,47	neutral	-6	neutral	0,27	medium_impact	-0,25	medium_impact	-0,23	low_impact	-1,21	0,63	0,8	2,31	7,56	N	0,44	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4513	4513	C	A	MI.12846	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	44	15	A	E	gCa/gAa	-8,72	0	0	benign	0,36	deleterious	0,03	neutral	4,06	deleterious	-3,52	neutral	-1,49	low_impact	1,45	neutral	0,89	neutral	0,56	deleterious	2,42	18,95	0,04	0,35	disease	0,56	disease	0,74	disease	0,71	disease	0,77	5	neutral	0,97	neutral	0,34	neutral	-2	deleterious	0,49	medium_impact	-0,57	medium_impact	-0,63	medium_impact	0,08	0,35	0,8	2,31	7,56	N	0,43	N	0,27	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4513	4513	C	G	MI.12847	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	44	15	A	G	gCa/gGa	-8,72	0	0	benign	0,26	neutral	0,14	neutral	4,09	neutral	-2,45	neutral	-2,05	neutral_impact	0,75	neutral	0,88	neutral	0,56	deleterious	1,9	15,6	0,25	0,45	disease	0,67	neutral	0,48	disease	0,54	disease	0,66	3	neutral	0,83	neutral	0,44	neutral	-6	neutral	0,37	medium_impact	-0,38	medium_impact	-0,23	medium_impact	-0,51	0,66	0,8	2,31	7,56	N	0,39	N	0,3	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4515	4515	G	T	MI.12848	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	46	16	G	C	Ggc/Tgc	-0,89	0	0	probably_damaging	1	neutral	0,18	neutral	3,69	deleterious	-5,25	deleterious	-7,92	high_impact	3,94	neutral	0,75	damaging	0,07	deleterious	3,93	23,5	0,03	0,35	disease	0,84	disease	0,87	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	-0,16	high_impact	2,17	0,19	0,8	NA	NA	N	0,39	N	0,96	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4515	4515	G	A	MI.12849	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	46	16	G	S	Ggc/Agc	-0,89	0	0	probably_damaging	1	neutral	0,51	neutral	3,78	deleterious	-3,13	deleterious	-5,1	medium_impact	2	neutral	0,82	neutral	0,57	deleterious	3,9	23,5	0,07	0,35	neutral	0,18	disease	0,81	disease	0,68	disease	0,64	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,22	medium_impact	0,54	0,64	0,8	NA	NA	N	0,3	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9130	9130	C	A	MI.1285	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	604	202	L	M	Cta/Ata	-14,91	0	0	probably_damaging	1	neutral	0,09	neutral	3,3	deleterious	-3,82	neutral	-1,79	medium_impact	3,44	damaging	0,38	neutral	0,62	deleterious	3,82	23,4	0,26	0,65	NA	NA	disease	0,63	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	-0,28	medium_impact	1,85	0,49	0,9	49,56	8,88	P	0,52	P	0,96	polymorphism	0,98	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4515	4515	G	C	MI.12850	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	46	16	G	R	Ggc/Cgc	-0,89	0	0	probably_damaging	1	neutral	0,35	neutral	3,71	deleterious	-4,3	deleterious	-7,04	high_impact	4,29	neutral	0,79	damaging	0,07	deleterious	3,75	23,3	0,03	0,35	neutral	0,45	disease	0,88	disease	0,85	disease	0,84	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	0,06	high_impact	2,47	0,57	0,8	NA	NA	N	0,43	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4516	4516	G	A	MI.12851	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	47	16	G	D	gGc/gAc	5,09	1	0	probably_damaging	1	neutral	0,2	neutral	3,7	deleterious	-4,79	deleterious	-6,13	high_impact	4,29	neutral	0,8	damaging	0,08	deleterious	3,63	23,2	0,03	0,35	neutral	0,46	disease	0,88	disease	0,84	disease	0,84	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	-0,13	high_impact	2,47	0,15	0,8	NA	NA	P	0,62	P	0,95	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4516	4516	G	T	MI.12852	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	47	16	G	V	gGc/gTc	5,09	1	0	probably_damaging	1	neutral	0,52	neutral	3,77	neutral	-2,95	deleterious	-7,96	high_impact	3,73	neutral	0,65	damaging	0,08	deleterious	3,56	23,1	0,03	0,35	disease	0,55	disease	0,87	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	0,23	medium_impact	2	0,15	0,8	NA	NA	P	0,61	P	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4516	4516	G	C	MI.12853	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	47	16	G	A	gGc/gCc	5,09	1	0	probably_damaging	1	neutral	0,52	neutral	3,78	neutral	-2,59	deleterious	-5,22	high_impact	3,59	neutral	0,75	damaging	0,1	deleterious	2,91	21,9	0,09	0,35	neutral	0,4	disease	0,63	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	0,23	medium_impact	1,88	0,37	0,8	NA	NA	P	0,56	P	0,74	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4518	4518	A	G	MI.12854	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	49	17	T	A	Aca/Gca	-7,34	0	0	probably_damaging	1	neutral	0,51	neutral	4,15	neutral	0,14	deleterious	-4,57	medium_impact	3,25	neutral	0,9	damaging	0,13	deleterious	3,24	22,8	0,19	0,45	neutral	0,31	disease	0,65	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0,22	medium_impact	1,59	0,44	0,8	2,31	7,6	N	0,33	N	0,79	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4518	4518	A	T	MI.12855	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	49	17	T	S	Aca/Tca	-7,34	0	0	probably_damaging	1	neutral	0,52	neutral	4,11	neutral	-0,66	deleterious	-3,65	medium_impact	2,58	neutral	0,92	neutral	0,32	deleterious	3,02	22,3	0,34	0,5	neutral	0,4	disease	0,67	disease	0,6	neutral	0,49	0	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,23	medium_impact	1,03	0,56	0,8	2,31	7,6	N	0,35	N	0,54	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4518	4518	A	C	MI.12856	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	49	17	T	P	Aca/Cca	-7,34	0	0	probably_damaging	1	neutral	0,22	neutral	4,03	neutral	-2,83	deleterious	-5,48	medium_impact	2,88	neutral	0,91	neutral	0,73	deleterious	2,19	17,47	0,04	0,35	neutral	0,43	disease	0,82	disease	0,62	disease	0,55	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,1	medium_impact	1,28	0,37	0,8	2,31	7,6	N	0,43	N	0,5	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4519	4519	C	T	MI.12857	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	50	17	T	M	aCa/aTa	2,33	0,94	0	probably_damaging	1	neutral	0,27	neutral	4,24	neutral	1,34	deleterious	-5,48	medium_impact	3,32	neutral	0,91	damaging	0,11	deleterious	3,8	23,4	0,12	0,4	disease	0,79	disease	0,81	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,03	medium_impact	1,65	0,52	0,8	2,31	7,6	N	0,45	N	0,92	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4519	4519	C	A	MI.12858	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	50	17	T	K	aCa/aAa	2,33	0,94	0	probably_damaging	1	neutral	0,28	neutral	4,04	neutral	-2,09	deleterious	-5,48	high_impact	4,29	neutral	0,9	damaging	0,1	deleterious	4,18	23,8	0,07	0,35	neutral	0,48	disease	0,86	disease	0,8	disease	0,8	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,02	high_impact	2,47	0,4	0,8	2,31	7,6	P	0,62	P	0,95	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4521	4521	C	T	MI.12859	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	52	18	L	F	Ctc/Ttc	-11,48	0	0	benign	0,04	neutral	0,8	neutral	4,01	neutral	-2,24	neutral	-2,07	low_impact	1,34	neutral	0,98	neutral	0,89	deleterious	2,52	19,61	0,22	0,45	neutral	0,19	disease	0,57	neutral	0,33	neutral	0,48	0	neutral	0,13	deleterious	0,88	neutral	-6	neutral	0,12	medium_impact	0,47	medium_impact	0,54	medium_impact	-0,02	0,65	0,8	4,61	7,28	N	0,32	N	0,16	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9130	9130	C	G	MI.1286	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	604	202	L	V	Cta/Gta	-14,91	0	0	probably_damaging	0,99	deleterious	0	neutral	3,3	deleterious	-3,68	deleterious	-2,69	high_impact	4,13	damaging	0,31	neutral	0,48	deleterious	3,5	23,1	0,28	0,65	NA	NA	disease	0,67	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,65	low_impact	-1,4	high_impact	2,44	0,49	0,9	49,56	8,88	P	0,6	P	0,87	polymorphism	0,98	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4521	4521	C	A	MI.12860	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	52	18	L	I	Ctc/Atc	-11,48	0	0	benign	0,03	neutral	0,6	neutral	4,11	neutral	-1,18	neutral	-0,75	neutral_impact	0,31	neutral	0,97	neutral	0,95	neutral	1,62	13,98	0,37	0,5	neutral	0,4	neutral	0,16	neutral	0,16	neutral	0,26	5	neutral	0,36	deleterious	0,79	neutral	-6	neutral	0,14	medium_impact	0,59	medium_impact	0,31	medium_impact	-0,88	0,63	0,8	4,61	7,28	N	0,45	N	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4521	4521	C	G	MI.12861	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	52	18	L	V	Ctc/Gtc	-11,48	0	0	benign	0,18	neutral	0,64	neutral	4,08	neutral	-1,22	neutral	-0,9	low_impact	1,29	neutral	0,89	neutral	0,96	neutral	1,39	12,72	0,31	0,45	neutral	0,36	neutral	0,31	neutral	0,24	neutral	0,46	1	neutral	0,24	deleterious	0,73	neutral	-6	neutral	0,27	medium_impact	-0,19	medium_impact	0,35	medium_impact	-0,06	0,66	0,8	4,61	7,28	N	0,38	N	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4522	4522	T	G	MI.12862	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	53	18	L	R	cTc/cGc	-0,89	0	0	possibly_damaging	0,81	neutral	0,35	neutral	3,95	deleterious	-3,83	deleterious	-3,07	medium_impact	3,09	neutral	0,82	neutral	0,43	deleterious	3,92	23,5	0,02	0,35	disease	0,74	disease	0,81	disease	0,71	disease	0,79	6	neutral	0,83	neutral	0,27	NA	0	deleterious	0,73	low_impact	-1,37	medium_impact	0,06	medium_impact	1,46	0,25	0,8	4,61	7,28	N	0,31	N	0,76	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4522	4522	T	C	MI.12863	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	53	18	L	P	cTc/cCc	-0,89	0	0	possibly_damaging	0,86	neutral	0,2	neutral	3,94	deleterious	-4,45	deleterious	-3,68	medium_impact	2,54	neutral	0,71	neutral	0,36	deleterious	3,71	23,3	0,02	0,35	disease	0,8	disease	0,83	disease	0,71	disease	0,81	6	neutral	0,91	neutral	0,17	NA	0	deleterious	0,77	low_impact	-1,52	medium_impact	-0,13	medium_impact	0,99	0,38	0,8	4,61	7,28	N	0,28	N	0,85	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4522	4522	T	A	MI.12864	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	53	18	L	H	cTc/cAc	-0,89	0	0	probably_damaging	0,93	neutral	0,55	neutral	3,95	deleterious	-4,21	deleterious	-3,82	medium_impact	3,09	neutral	0,84	neutral	0,47	deleterious	3,99	23,6	0,04	0,35	disease	0,8	disease	0,56	disease	0,57	disease	0,72	4	neutral	0,92	neutral	0,31	deleterious	1	deleterious	0,72	low_impact	-1,83	medium_impact	0,26	medium_impact	1,46	0,23	0,8	4,61	7,28	N	0,26	N	0,72	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4524	4524	A	G	MI.12865	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	55	19	I	V	Atc/Gtc	-2,73	0	0	benign	0,42	neutral	0,48	neutral	4,21	neutral	0,36	neutral	-0,73	medium_impact	2,31	neutral	0,93	neutral	0,79	neutral	1,55	13,6	0,59	0,65	neutral	0,49	neutral	0,45	neutral	0,38	neutral	0,43	1	neutral	0,47	deleterious	0,53	neutral	-3	neutral	0,31	medium_impact	-0,67	medium_impact	0,19	medium_impact	0,8	0,46	0,8	0,86	7,07	N	0,37	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4524	4524	A	T	MI.12866	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	55	19	I	F	Atc/Ttc	-2,73	0	0	probably_damaging	0,92	neutral	0,29	neutral	4,08	neutral	-0,8	deleterious	-3,23	medium_impact	2,66	neutral	0,84	neutral	0,4	deleterious	3,52	23,1	0,15	0,4	disease	0,67	disease	0,85	disease	0,63	disease	0,71	4	neutral	0,94	neutral	0,19	deleterious	1	deleterious	0,72	low_impact	-1,77	medium_impact	-0,01	medium_impact	1,1	0,59	0,8	0,86	7,07	N	0,31	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4524	4524	A	C	MI.12867	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	55	19	I	L	Atc/Ctc	-2,73	0	0	benign	0,42	neutral	0,98	neutral	4,3	neutral	1,01	neutral	-1,18	low_impact	1,16	neutral	0,91	neutral	0,93	neutral	1,75	14,69	0,27	0,45	neutral	0,33	neutral	0,4	neutral	0,25	neutral	0,44	1	neutral	0,39	deleterious	0,78	neutral	-6	neutral	0,43	medium_impact	-0,67	medium_impact	1,15	medium_impact	-0,17	0,59	0,8	0,86	7,07	N	0,3	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4525	4525	T	A	MI.12868	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	56	19	I	N	aTc/aAc	-0,2	0	0	possibly_damaging	0,9	neutral	0,07	neutral	3,99	neutral	-2,63	deleterious	-5,78	high_impact	3,98	neutral	0,89	neutral	0,47	deleterious	4,22	23,9	0,07	0,35	disease	0,75	disease	0,87	disease	0,62	disease	0,71	4	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,75	low_impact	-1,67	medium_impact	-0,42	high_impact	2,21	0,45	0,8	0,86	7,07	N	0,52	P	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4525	4525	T	G	MI.12869	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	56	19	I	S	aTc/aGc	-0,2	0	0	possibly_damaging	0,54	neutral	0,56	neutral	4,02	neutral	-1,91	deleterious	-4,87	high_impact	3,63	neutral	0,84	neutral	0,47	deleterious	4,02	23,6	0,02	0,35	neutral	0,34	disease	0,84	disease	0,62	disease	0,71	4	neutral	0,5	deleterious	0,51	deleterious	1	deleterious	0,53	medium_impact	-0,86	medium_impact	0,27	medium_impact	1,91	0,37	0,8	0,86	7,07	N	0,29	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9131	9131	T	C	MI.1287	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	605	202	L	P	cTa/cCa	0,13	0	0	probably_damaging	1	deleterious	0	neutral	3,25	deleterious	-6,45	deleterious	-6,3	high_impact	4,13	damaging	0,19	neutral	0,47	deleterious	4,01	23,6	0,15	0,65	NA	NA	disease	0,86	disease	0,72	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,6	low_impact	-1,4	high_impact	2,44	0,49	0,9	49,56	8,88	P	0,9	P	1	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4525	4525	T	C	MI.12870	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	56	19	I	T	aTc/aCc	-0,2	0	0	benign	0,06	neutral	0,31	neutral	4,04	neutral	-1,41	deleterious	-3,88	medium_impact	2,08	neutral	0,92	neutral	0,94	deleterious	3,09	22,5	0,06	0,35	neutral	0,5	disease	0,65	neutral	0,41	neutral	0,47	1	neutral	0,66	deleterious	0,63	neutral	-3	neutral	0,23	medium_impact	0,3	medium_impact	0,02	medium_impact	0,61	0,26	0,8	0,86	7,07	N	0,42	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4526	4526	C	A	MI.12871	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	57	19	I	M	atC/atA	4,63	0,65	0	probably_damaging	0,95	neutral	0,37	neutral	4,07	neutral	-0,78	neutral	-1,98	low_impact	1,72	neutral	0,89	neutral	0,93	deleterious	2,29	18,13	0,31	0,45	disease	0,63	disease	0,51	neutral	0,31	neutral	0,48	0	neutral	0,95	neutral	0,21	neutral	-2	deleterious	0,68	low_impact	-1,97	medium_impact	0,08	medium_impact	0,3	0,55	0,8	0,86	7,07	N	0,45	N	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4526	4526	C	G	MI.12872	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	57	19	I	M	atC/atG	4,63	0,65	0	probably_damaging	0,95	neutral	0,37	neutral	4,07	neutral	-0,78	neutral	-1,98	low_impact	1,72	neutral	0,89	neutral	0,93	deleterious	1,85	15,28	0,31	0,45	disease	0,63	disease	0,51	neutral	0,31	neutral	0,48	0	neutral	0,95	neutral	0,21	neutral	-2	deleterious	0,68	low_impact	-1,97	medium_impact	0,08	medium_impact	0,3	0,55	0,8	0,86	7,07	N	0,45	N	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4527	4527	A	C	MI.12873	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	58	20	T	P	Aca/Cca	-8,95	0	0	probably_damaging	0,95	neutral	0,2	neutral	4,06	neutral	-2,89	deleterious	-3,16	medium_impact	3,37	neutral	0,81	neutral	0,4	neutral	1,64	14,05	0,04	0,35	disease	0,75	disease	0,86	disease	0,77	disease	0,78	6	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,78	low_impact	-1,97	medium_impact	-0,13	medium_impact	1,69	0,32	0,8	1,15	11,16	N	0,39	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4527	4527	A	G	MI.12874	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	58	20	T	A	Aca/Gca	-8,95	0	0	benign	0,11	neutral	0,48	neutral	4,17	neutral	0,3	neutral	-1,48	low_impact	0,89	neutral	0,93	neutral	0,8	deleterious	0,23	5	0,19	0,45	neutral	0,39	disease	0,56	disease	0,55	neutral	0,46	1	neutral	0,44	deleterious	0,69	neutral	-6	neutral	0,19	medium_impact	0,03	medium_impact	0,19	medium_impact	-0,4	0,49	0,8	1,15	11,16	N	0,3	N	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4527	4527	A	T	MI.12875	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	58	20	T	S	Aca/Tca	-8,95	0	0	possibly_damaging	0,72	neutral	0,55	neutral	4,15	neutral	-0,58	neutral	-2,29	low_impact	1,22	neutral	0,91	neutral	0,6	neutral	1,18	11,63	0,31	0,45	neutral	0,49	disease	0,71	disease	0,62	disease	0,65	3	neutral	0,68	neutral	0,42	neutral	-3	deleterious	0,59	low_impact	-1,17	medium_impact	0,26	medium_impact	-0,12	0,68	0,85	1,15	11,16	N	0,3	N	0,64	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4528	4528	C	T	MI.12876	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	59	20	T	M	aCa/aTa	4,63	0,98	0	probably_damaging	0,98	neutral	0,27	neutral	4,26	neutral	1,01	neutral	-1,62	medium_impact	2,82	neutral	0,91	neutral	0,51	deleterious	3,64	23,2	0,08	0,35	disease	0,57	disease	0,77	disease	0,66	disease	0,69	4	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,71	low_impact	-2,34	medium_impact	-0,03	medium_impact	1,23	0,71	0,85	1,15	11,16	P	0,57	P	0,82	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4528	4528	C	A	MI.12877	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	59	20	T	K	aCa/aAa	4,63	0,98	0	probably_damaging	0,91	neutral	0,26	neutral	4,07	neutral	-2,31	deleterious	-3,16	medium_impact	3,02	neutral	0,88	neutral	0,45	deleterious	2,46	19,19	0,05	0,35	disease	0,63	disease	0,86	disease	0,77	disease	0,78	6	neutral	0,93	neutral	0,18	deleterious	1	deleterious	0,74	low_impact	-1,72	medium_impact	-0,04	medium_impact	1,4	0,43	0,8	1,15	11,16	P	0,6	P	0,95	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4530	4530	G	T	MI.12878	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	61	21	A	S	Gcg/Tcg	-12,17	0	0	benign	0,02	neutral	0,72	neutral	4,07	neutral	-2,05	neutral	-0,22	low_impact	0,95	neutral	0,92	neutral	0,65	deleterious	3,42	23	0,19	0,45	neutral	0,39	neutral	0,38	neutral	0,46	neutral	0,47	1	neutral	0,24	deleterious	0,85	neutral	-6	neutral	0,14	medium_impact	0,75	medium_impact	0,44	medium_impact	-0,35	0,57	0,8	1,73	8,04	N	0,31	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4530	4530	G	A	MI.12879	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	61	21	A	T	Gcg/Acg	-12,17	0	0	benign	0,01	neutral	0,52	neutral	4,08	neutral	-1,77	neutral	0,1	neutral_impact	0,38	neutral	0,92	neutral	0,94	deleterious	2,83	21,5	0,15	0,45	neutral	0,27	neutral	0,31	neutral	0,45	neutral	0,45	1	neutral	0,47	deleterious	0,76	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	0,23	medium_impact	-0,83	0,68	0,85	1,73	8,04	N	0,35	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9131	9131	T	A	MI.1288	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	605	202	L	Q	cTa/cAa	0,13	0	0	probably_damaging	1	deleterious	0	neutral	3,25	deleterious	-6,49	deleterious	-5,38	high_impact	4,47	damaging	0,36	neutral	0,48	deleterious	4,18	23,8	0,15	0,65	NA	NA	disease	0,81	disease	0,66	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,6	low_impact	-1,4	high_impact	2,73	0,47	0,9	49,56	8,88	P	0,64	P	0,98	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4530	4530	G	C	MI.12880	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	61	21	A	P	Gcg/Ccg	-12,17	0	0	possibly_damaging	0,64	neutral	0,19	neutral	4,02	deleterious	-3,31	neutral	-1,39	medium_impact	2,04	neutral	0,83	neutral	0,37	deleterious	3,65	23,2	0,04	0,35	disease	0,63	disease	0,82	disease	0,69	disease	0,8	6	neutral	0,82	neutral	0,28	NA	0	deleterious	0,6	low_impact	-1,03	medium_impact	-0,14	medium_impact	0,57	0,6	0,8	1,73	8,04	N	0,25	N	0,7	polymorphism	1	0,03	rs28739288	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4531	4531	C	T	MI.12881	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	62	21	A	V	gCg/gTg	-1,58	0	0	benign	0,08	neutral	0,52	neutral	4,26	neutral	-0,11	neutral	1,35	neutral_impact	0,16	neutral	0,97	neutral	0,95	deleterious	4,14	23,8	0,15	0,4	neutral	0,21	neutral	0,44	neutral	0,37	neutral	0,45	1	neutral	0,41	deleterious	0,72	neutral	-6	neutral	0,14	medium_impact	0,17	medium_impact	0,23	low_impact	-1,01	0,68	0,85	1,73	8,04	N	0,31	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4531	4531	C	G	MI.12882	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	62	21	A	G	gCg/gGg	-1,58	0	0	benign	0,19	neutral	0,36	neutral	4,03	deleterious	-3,58	neutral	-2,15	low_impact	1,5	neutral	0,89	neutral	0,59	deleterious	3,7	23,3	0,12	0,4	disease	0,55	neutral	0,48	disease	0,53	disease	0,63	3	neutral	0,57	deleterious	0,59	neutral	-6	neutral	0,27	medium_impact	-0,22	medium_impact	0,07	medium_impact	0,12	0,57	0,8	1,73	8,04	N	0,37	N	0,5	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4531	4531	C	A	MI.12883	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	62	21	A	E	gCg/gAg	-1,58	0	0	benign	0,35	neutral	0,3	neutral	4,01	deleterious	-4	neutral	-1,35	medium_impact	2,04	neutral	0,92	neutral	0,59	deleterious	4,35	24,1	0,03	0,35	disease	0,52	disease	0,74	disease	0,68	disease	0,75	5	neutral	0,64	deleterious	0,48	neutral	-3	deleterious	0,45	medium_impact	-0,55	medium_impact	0	medium_impact	0,57	0,51	0,8	1,73	8,04	N	0,34	N	0,67	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4533	4533	C	A	MI.12884	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	64	22	L	M	Cta/Ata	-2,27	0	0	benign	0,32	neutral	0,24	neutral	4,08	neutral	-2,68	neutral	-0,14	neutral_impact	-0,82	neutral	0,96	neutral	0,81	deleterious	0,58	8	0,25	0,45	neutral	0,46	neutral	0,23	neutral	0,28	neutral	0,43	1	neutral	0,71	neutral	0,46	neutral	-6	neutral	0,35	medium_impact	-0,5	medium_impact	-0,07	low_impact	-1,84	0,55	0,8	4,03	7,25	N	0,5	N	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4533	4533	C	G	MI.12885	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	64	22	L	V	Cta/Gta	-2,27	0	0	possibly_damaging	0,56	neutral	0,53	neutral	4,15	neutral	-1,3	neutral	-0,23	neutral_impact	0,3	neutral	0,92	neutral	0,89	neutral	-1,41	0	0,24	0,45	neutral	0,47	neutral	0,41	neutral	0,37	neutral	0,44	1	neutral	0,53	deleterious	0,49	neutral	-3	deleterious	0,46	medium_impact	-0,89	medium_impact	0,24	medium_impact	-0,89	0,54	0,8	4,03	7,25	N	0,34	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4534	4534	T	C	MI.12886	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	65	22	L	P	cTa/cCa	-2,5	0	0	probably_damaging	0,9	neutral	0,21	neutral	4,04	deleterious	-4,22	deleterious	-3,28	low_impact	0,85	neutral	0,69	neutral	0,41	deleterious	0,71	8,92	0,03	0,35	disease	0,83	disease	0,85	disease	0,64	disease	0,82	6	neutral	0,94	neutral	0,16	neutral	-2	deleterious	0,8	low_impact	-1,67	medium_impact	-0,11	medium_impact	-0,43	0,24	0,8	4,03	7,25	N	0,28	N	0,9	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4534	4534	T	G	MI.12887	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	65	22	L	R	cTa/cGa	-2,5	0	0	possibly_damaging	0,87	neutral	0,35	neutral	4,06	deleterious	-3,41	deleterious	-2,87	low_impact	1,2	neutral	0,81	neutral	0,48	deleterious	2,03	16,41	0,03	0,35	disease	0,77	disease	0,85	disease	0,71	disease	0,8	6	neutral	0,88	neutral	0,24	neutral	-3	deleterious	0,78	low_impact	-1,55	medium_impact	0,06	medium_impact	-0,13	0,19	0,8	4,03	7,25	N	0,28	N	0,79	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4534	4534	T	A	MI.12888	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	65	22	L	Q	cTa/cAa	-2,5	0	0	probably_damaging	0,9	neutral	0,3	neutral	4,06	deleterious	-3,01	deleterious	-2,74	low_impact	1,2	neutral	0,85	neutral	0,56	neutral	0,99	10,58	0,04	0,35	disease	0,79	disease	0,6	neutral	0,5	disease	0,56	1	neutral	0,92	neutral	0,2	neutral	-2	deleterious	0,71	low_impact	-1,67	medium_impact	0	medium_impact	-0,13	0,26	0,8	4,03	7,25	N	0,31	N	0,81	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4536	4536	A	T	MI.12889	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	67	23	S	C	Agc/Tgc	-6,19	0	0	probably_damaging	1	neutral	0,05	neutral	3,85	deleterious	-4,57	deleterious	-4,41	medium_impact	3,1	neutral	0,89	damaging	0,11	deleterious	3,19	22,7	0,04	0,35	disease	0,8	disease	0,86	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,5	medium_impact	1,47	0,3	0,8	NA	NA	N	0,4	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9131	9131	T	G	MI.1289	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	605	202	L	R	cTa/cGa	0,13	0	0	probably_damaging	1	deleterious	0	neutral	3,25	deleterious	-6,16	deleterious	-5,38	high_impact	4,47	damaging	0,45	neutral	0,43	deleterious	4,27	24	0,14	0,65	NA	NA	disease	0,91	disease	0,76	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,93	low_impact	-3,6	low_impact	-1,4	high_impact	2,73	0,32	0,9	49,56	8,88	N	0,55	P	0,99	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4536	4536	A	C	MI.12890	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	67	23	S	R	Agc/Cgc	-6,19	0	0	probably_damaging	1	neutral	0,1	neutral	3,82	deleterious	-6,18	deleterious	-4,44	high_impact	3,91	neutral	0,87	damaging	0,09	deleterious	3,62	23,2	0,04	0,35	disease	0,74	disease	0,9	disease	0,82	disease	0,8	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	-0,32	high_impact	2,15	0,32	0,8	NA	NA	N	0,47	N	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4536	4536	A	G	MI.12891	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	67	23	S	G	Agc/Ggc	-6,19	0	0	probably_damaging	1	neutral	0,09	neutral	3,84	deleterious	-5,04	deleterious	-3,54	medium_impact	3,36	neutral	0,94	neutral	0,28	deleterious	3,31	22,9	0,08	0,35	disease	0,7	disease	0,69	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,35	medium_impact	1,68	0,35	0,8	NA	NA	N	0,46	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4537	4537	G	A	MI.12892	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	68	23	S	N	aGc/aAc	6,71	1	0	probably_damaging	1	neutral	0,16	neutral	3,82	deleterious	-5,85	deleterious	-2,72	medium_impact	3,36	neutral	0,9	damaging	0,13	deleterious	3,4	23	0,17	0,45	disease	0,76	disease	0,83	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	-0,19	medium_impact	1,68	0,27	0,8	NA	NA	P	0,65	P	0,89	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4537	4537	G	C	MI.12893	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	68	23	S	T	aGc/aCc	6,71	1	0	probably_damaging	1	neutral	0,14	neutral	3,85	deleterious	-4,62	deleterious	-2,62	medium_impact	2,39	neutral	0,96	neutral	0,54	deleterious	3,15	22,6	0,11	0,4	neutral	0,49	disease	0,67	disease	0,69	disease	0,59	2	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,23	medium_impact	0,87	0,5	0,8	NA	NA	P	0,65	P	0,71	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4537	4537	G	T	MI.12894	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	68	23	S	I	aGc/aTc	6,71	1	0	probably_damaging	1	neutral	0,15	neutral	3,82	deleterious	-5,83	deleterious	-5,32	high_impact	3,56	neutral	0,91	damaging	0,12	deleterious	3,87	23,5	0,04	0,35	neutral	0,35	disease	0,92	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	-0,21	medium_impact	1,85	0,31	0,8	NA	NA	P	0,6	P	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4539	4539	T	G	MI.12895	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	70	24	S	A	Tcg/Gcg	-0,2	0,01	0	probably_damaging	1	neutral	0,51	neutral	4,52	neutral	0,13	deleterious	-2,72	medium_impact	2,44	neutral	0,91	neutral	0,62	deleterious	3,48	23,1	0,22	0,45	neutral	0,42	disease	0,63	disease	0,65	disease	0,69	4	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0,22	medium_impact	0,91	0,35	0,8	NA	NA	N	0,35	N	0,41	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4539	4539	T	C	MI.12896	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	70	24	S	P	Tcg/Ccg	-0,2	0,01	0	probably_damaging	1	neutral	0,2	neutral	4,48	neutral	-2,34	deleterious	-4,47	low_impact	1,78	neutral	0,9	neutral	0,43	deleterious	3,75	23,3	0,05	0,35	neutral	0,22	disease	0,91	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	-0,13	medium_impact	0,35	0,2	0,8	NA	NA	N	0,41	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4539	4539	T	A	MI.12897	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	70	24	S	T	Tcg/Acg	-0,2	0,01	0	probably_damaging	1	neutral	0,4	neutral	4,52	neutral	-0,3	deleterious	-2,58	low_impact	1,31	neutral	0,88	neutral	0,89	deleterious	2,49	19,38	0,19	0,45	neutral	0,38	disease	0,51	neutral	0,45	neutral	0,35	3	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,7	low_impact	-3,54	medium_impact	0,11	medium_impact	-0,04	0,45	0,8	NA	NA	N	0,37	N	0,23	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4540	4540	C	T	MI.12898	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	71	24	S	L	tCg/tTg	0,49	0	0	probably_damaging	1	neutral	0,69	neutral	4,53	neutral	-0,9	deleterious	-5,37	medium_impact	2,86	neutral	0,9	neutral	0,48	deleterious	4,46	24,2	0,09	0,4	disease	0,55	disease	0,86	disease	0,62	disease	0,72	4	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	0,4	medium_impact	1,26	0,52	0,8	NA	NA	N	0,32	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4540	4540	C	G	MI.12899	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	71	24	S	W	tCg/tGg	0,49	0	0	probably_damaging	1	neutral	0,24	neutral	4,45	deleterious	-4,25	deleterious	-6,29	medium_impact	3,41	neutral	0,88	neutral	0,44	deleterious	4,17	23,8	0,06	0,35	disease	0,9	disease	0,92	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	-0,07	medium_impact	1,73	0,14	0,8	NA	NA	N	0,39	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8587	8587	G	T	MI.129	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	61	21	V	L	Gta/Tta	-8,2	0	0	benign	0,19	neutral	0,58	neutral	4,6	neutral	1,18	neutral	-0,64	neutral_impact	-1,18	neutral	0,91	neutral	0,96	neutral	-0,54	0,18	0,48	0,65	neutral	0,32	neutral	0,16	neutral	0,21	neutral	0,27	5	neutral	0,31	deleterious	0,7	neutral	-6	neutral	0,19	medium_impact	-0,16	medium_impact	0,37	low_impact	-2,11	0,64	0,9	22,57	20,88	N	0,36	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9133	9133	G	C	MI.1290	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	607	203	E	Q	Gaa/Caa	-4,04	0	0	probably_damaging	0,99	deleterious	0	neutral	3,42	deleterious	-4,06	deleterious	-2,66	high_impact	4,23	damaging	0,49	neutral	0,55	deleterious	3,41	23	0,38	0,65	NA	NA	disease	0,77	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,65	low_impact	-1,4	high_impact	2,53	0,64	0,9	48,67	8,97	N	0,49	N	0,91	disease_causing	0,98	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4542	4542	C	T	MI.12900	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	73	25	H	Y	Cac/Tac	-3,42	0	0	probably_damaging	1	neutral	1	neutral	4,58	neutral	-2,79	deleterious	-5,4	medium_impact	3,17	neutral	0,86	damaging	0,09	deleterious	3,55	23,1	0,1	0,4	disease	0,55	disease	0,87	disease	0,78	disease	0,73	5	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,82	low_impact	-3,54	high_impact	1,87	medium_impact	1,52	0,31	0,8	0,58	7,17	N	0,29	N	0,86	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4542	4542	C	G	MI.12901	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	73	25	H	D	Cac/Gac	-3,42	0	0	probably_damaging	1	neutral	0,2	neutral	4,97	neutral	2,68	deleterious	-7,95	medium_impact	3,03	neutral	0,88	damaging	0,1	deleterious	3,66	23,2	0,05	0,35	neutral	0,48	disease	0,83	disease	0,82	disease	0,75	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,13	medium_impact	1,41	0,37	0,8	0,58	7,17	N	0,43	N	0,91	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4542	4542	C	A	MI.12902	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	73	25	H	N	Cac/Aac	-3,42	0	0	probably_damaging	1	neutral	0,49	neutral	5,02	neutral	2,89	deleterious	-6,01	low_impact	1,64	neutral	0,89	neutral	0,7	deleterious	2,6	20,2	0,22	0,45	neutral	0,23	disease	0,81	disease	0,75	neutral	0,44	1	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	0,2	medium_impact	0,24	0,38	0,8	0,58	7,17	N	0,36	N	0,63	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4543	4543	A	T	MI.12903	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	74	25	H	L	cAc/cTc	2,1	0,95	0	probably_damaging	1	neutral	0,71	neutral	4,59	neutral	-1,83	deleterious	-9,85	medium_impact	3,38	neutral	0,84	damaging	0,09	deleterious	3,62	23,2	0,04	0,35	neutral	0,23	disease	0,89	disease	0,78	disease	0,7	4	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,42	medium_impact	1,7	0,2	0,8	0,58	7,17	N	0,46	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4543	4543	A	C	MI.12904	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	74	25	H	P	cAc/cCc	2,1	0,95	0	probably_damaging	1	neutral	0,25	neutral	4,59	neutral	-1,99	deleterious	-8,93	high_impact	3,73	neutral	0,84	damaging	0,1	deleterious	3,04	22,4	0,03	0,35	disease	0,63	disease	0,87	disease	0,84	disease	0,76	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,06	medium_impact	2	0,19	0,8	0,58	7,17	P	0,56	P	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4543	4543	A	G	MI.12905	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	74	25	H	R	cAc/cGc	2,1	0,95	0	probably_damaging	1	neutral	0,36	neutral	4,61	neutral	-0,99	deleterious	-7,1	high_impact	3,73	neutral	0,86	damaging	0,1	deleterious	2,77	21,2	0,08	0,35	neutral	0,45	disease	0,85	disease	0,81	disease	0,73	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	0,07	medium_impact	2	0,41	0,8	0,58	7,17	N	0,49	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4544	4544	C	G	MI.12906	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	75	25	H	Q	caC/caG	4,63	0,99	0	probably_damaging	1	neutral	0,29	neutral	4,62	neutral	-0,51	deleterious	-7,1	medium_impact	3,03	neutral	0,9	damaging	0,11	deleterious	3,36	22,9	0,11	0,4	neutral	0,43	disease	0,8	disease	0,78	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,41	0,29	0,8	0,58	7,17	P	0,57	P	0,8	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4544	4544	C	A	MI.12907	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	75	25	H	Q	caC/caA	4,63	0,99	0	probably_damaging	1	neutral	0,29	neutral	4,62	neutral	-0,51	deleterious	-7,1	medium_impact	3,03	neutral	0,9	damaging	0,11	deleterious	3,63	23,2	0,11	0,4	neutral	0,43	disease	0,8	disease	0,78	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,41	0,29	0,8	0,58	7,17	P	0,58	P	0,8	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4545	4545	T	C	MI.12908	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	76	26	W	R	Tga/Cga	0,03	0,96	0	probably_damaging	1	neutral	0,23	neutral	4,54	neutral	-2,58	deleterious	-12,83	high_impact	3,96	neutral	0,78	damaging	0,11	deleterious	3,38	23	0,03	0,35	disease	0,65	disease	0,9	disease	0,84	disease	0,77	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	-0,08	high_impact	2,19	0,13	0,8	2,59	8,07	P	0,52	P	0,98	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4545	4545	T	G	MI.12909	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	76	26	W	G	Tga/Gga	0,03	0,96	0	probably_damaging	1	neutral	0,26	neutral	4,54	neutral	-2,63	deleterious	-11,91	high_impact	3,96	neutral	0,9	damaging	0,12	deleterious	3,65	23,2	0,04	0,35	disease	0,66	disease	0,84	disease	0,81	disease	0,74	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	-0,04	high_impact	2,19	0,08	0,8	2,59	8,07	P	0,58	P	0,9	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9133	9133	G	A	MI.1291	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	607	203	E	K	Gaa/Aaa	-4,04	0	0	probably_damaging	0,99	deleterious	0	neutral	3,44	deleterious	-3,55	deleterious	-3,55	high_impact	3,6	damaging	0,52	neutral	0,44	deleterious	4,56	24,4	0,28	0,65	NA	NA	disease	0,9	disease	0,78	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,92	low_impact	-2,65	low_impact	-1,4	medium_impact	1,99	0,66	0,9	48,67	8,97	N	0,43	N	1	disease_causing	1	0,3	.	.	.	.	.	.	COSM1138418	.	.	.	.	.	.	.	.
chrM	4546	4546	G	T	MI.12910	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	77	26	W	L	tGa/tTa	2,33	1	0	probably_damaging	1	neutral	0,58	neutral	5,18	neutral	2,72	deleterious	-11,91	medium_impact	2,34	neutral	0,94	neutral	0,62	deleterious	2,96	22,1	0,08	0,35	neutral	0,22	disease	0,83	disease	0,76	disease	0,58	2	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,29	medium_impact	0,83	0,08	0,8	2,59	8,07	N	0,47	N	0,65	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4546	4546	G	C	MI.12911	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	77	26	W	S	tGa/tCa	2,33	1	0	probably_damaging	1	neutral	0,64	neutral	4,56	neutral	-1,62	deleterious	-12,83	medium_impact	3,42	neutral	0,78	damaging	0,12	deleterious	3,87	23,5	0,04	0,35	neutral	0,47	disease	0,89	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	0,35	medium_impact	1,73	0,06	0,8	2,59	8,07	N	0,47	N	0,95	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4547	4547	A	C	MI.12912	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	78	26	W	C	tgA/tgC	5,78	1	0	probably_damaging	1	neutral	0,11	neutral	4,56	neutral	-1,81	deleterious	-11,91	high_impact	3,96	neutral	0,75	damaging	0,1	deleterious	3,84	23,4	0,04	0,35	disease	0,61	disease	0,89	disease	0,82	disease	0,76	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,3	high_impact	2,19	0,15	0,8	2,59	8,07	P	0,66	P	0,89	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4547	4547	A	T	MI.12913	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	78	26	W	C	tgA/tgT	5,78	1	0	probably_damaging	1	neutral	0,11	neutral	4,56	neutral	-1,81	deleterious	-11,91	high_impact	3,96	neutral	0,75	damaging	0,1	deleterious	3,92	23,5	0,04	0,35	disease	0,61	disease	0,89	disease	0,82	disease	0,76	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,3	high_impact	2,19	0,15	0,8	2,59	8,07	P	0,66	P	0,89	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4548	4548	T	G	MI.12914	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	79	27	F	V	Ttt/Gtt	1,64	0,79	0	possibly_damaging	0,56	neutral	0,38	neutral	4,58	neutral	-0,6	neutral	-0,95	low_impact	1,26	neutral	0,86	neutral	0,69	deleterious	2,17	17,32	0,07	0,35	neutral	0,25	disease	0,52	disease	0,54	neutral	0,4	2	neutral	0,63	neutral	0,41	neutral	-3	deleterious	0,55	medium_impact	-0,89	medium_impact	0,09	medium_impact	-0,08	0,32	0,8	0,29	7,84	N	0,34	N	0,6	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4548	4548	T	A	MI.12915	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	79	27	F	I	Ttt/Att	1,64	0,79	0	benign	0,43	neutral	0,36	neutral	4,82	neutral	1,07	neutral	-0,04	low_impact	1	neutral	0,87	neutral	0,77	neutral	1,34	12,46	0,15	0,4	neutral	0,2	disease	0,5	neutral	0,37	neutral	0,24	5	neutral	0,59	neutral	0,47	neutral	-6	deleterious	0,52	medium_impact	-0,69	medium_impact	0,07	medium_impact	-0,3	0,49	0,8	0,29	7,84	N	0,35	N	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4548	4548	T	C	MI.12916	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	79	27	F	L	Ttt/Ctt	1,64	0,79	0	benign	0,04	neutral	1	neutral	4,89	neutral	1,33	neutral	1,32	neutral_impact	-0,38	neutral	0,92	neutral	0,98	neutral	-0,7	0,07	0,14	0,4	neutral	0,34	neutral	0,21	neutral	0,26	neutral	0,36	3	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,14	medium_impact	0,47	high_impact	1,87	low_impact	-1,46	0,71	0,85	0,29	7,84	N	0,3	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4549	4549	T	A	MI.12917	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	80	27	F	Y	tTt/tAt	-4,35	0	0	possibly_damaging	0,77	neutral	0,62	neutral	4,48	neutral	-2,9	neutral	-1,38	medium_impact	2,34	neutral	0,9	neutral	0,52	deleterious	2,72	20,9	0,11	0,4	disease	0,5	disease	0,62	disease	0,58	disease	0,69	4	neutral	0,73	neutral	0,43	NA	0	deleterious	0,68	low_impact	-1,28	medium_impact	0,33	medium_impact	0,83	0,62	0,8	0,29	7,84	N	0,34	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4549	4549	T	G	MI.12918	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	80	27	F	C	tTt/tGt	-4,35	0	0	probably_damaging	0,97	neutral	0,1	neutral	4,47	deleterious	-3,69	deleterious	-2,55	medium_impact	3,03	neutral	0,86	neutral	0,4	deleterious	3,91	23,5	0,02	0,35	disease	0,63	disease	0,81	disease	0,61	disease	0,74	5	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,74	low_impact	-2,18	medium_impact	-0,32	medium_impact	1,41	0,23	0,8	0,29	7,84	N	0,34	N	0,71	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4549	4549	T	C	MI.12919	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	80	27	F	S	tTt/tCt	-4,35	0	0	probably_damaging	0,9	neutral	0,45	neutral	4,49	neutral	-2,42	deleterious	-3,23	medium_impact	2,34	neutral	0,84	neutral	0,53	deleterious	3,86	23,5	0,02	0,35	neutral	0,38	disease	0,66	disease	0,62	disease	0,7	4	neutral	0,9	neutral	0,28	deleterious	1	deleterious	0,69	low_impact	-1,67	medium_impact	0,16	medium_impact	0,83	0,37	0,8	0,29	7,84	N	0,26	N	0,78	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9134	9134	A	C	MI.1292	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	608	203	E	A	gAa/gCa	9,38	1	0	probably_damaging	0,99	deleterious	0	neutral	3,43	deleterious	-4,06	deleterious	-5,3	high_impact	4,58	damaging	0,56	neutral	0,55	deleterious	3,62	23,2	0,21	0,65	NA	NA	disease	0,72	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,65	low_impact	-1,4	high_impact	2,83	0,46	0,9	48,67	8,97	P	0,53	P	0,8	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4550	4550	T	G	MI.12920	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	81	27	F	L	ttT/ttG	4,4	0,64	0	benign	0,04	neutral	1	neutral	4,89	neutral	1,33	neutral	1,32	neutral_impact	-0,38	neutral	0,92	neutral	0,98	neutral	-0,64	0,1	0,14	0,4	neutral	0,34	neutral	0,21	neutral	0,26	neutral	0,36	3	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,14	medium_impact	0,47	high_impact	1,87	low_impact	-1,46	0,71	0,85	0,29	7,84	N	0,36	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4550	4550	T	A	MI.12921	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	81	27	F	L	ttT/ttA	4,4	0,64	0	benign	0,04	neutral	1	neutral	4,89	neutral	1,33	neutral	1,32	neutral_impact	-0,38	neutral	0,92	neutral	0,98	neutral	-0,45	0,3	0,14	0,4	neutral	0,34	neutral	0,21	neutral	0,26	neutral	0,36	3	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,14	medium_impact	0,47	high_impact	1,87	low_impact	-1,46	0,71	0,85	0,29	7,84	N	0,37	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4551	4551	T	A	MI.12922	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	82	28	F	I	Ttt/Att	-12,86	0	0	benign	0	neutral	0,29	neutral	4,74	neutral	0,42	neutral	1,13	neutral_impact	-0,12	neutral	0,91	neutral	0,64	deleterious	2,16	17,23	0,14	0,4	neutral	0,48	disease	0,64	neutral	0,44	neutral	0,35	3	neutral	0,71	deleterious	0,65	neutral	-6	neutral	0,2	medium_impact	1,95	medium_impact	-0,01	low_impact	-1,25	0,52	0,8	NA	NA	N	0,37	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4551	4551	T	G	MI.12923	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	82	28	F	V	Ttt/Gtt	-12,86	0	0	benign	0,01	neutral	0,45	neutral	4,73	neutral	0,94	neutral	0,76	neutral_impact	0,33	neutral	0,93	neutral	0,9	deleterious	0,77	9,28	0,12	0,4	neutral	0,46	disease	0,63	neutral	0,46	neutral	0,42	2	neutral	0,53	deleterious	0,72	neutral	-6	neutral	0,19	medium_impact	1,03	medium_impact	0,16	medium_impact	-0,87	0,43	0,8	NA	NA	N	0,3	N	0,55	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4551	4551	T	C	MI.12924	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	82	28	F	L	Ttt/Ctt	-12,86	0	0	benign	0	neutral	1	neutral	4,91	neutral	1,47	neutral	2,27	neutral_impact	-1,26	neutral	0,97	neutral	0,97	neutral	-0,93	0,02	0,16	0,45	neutral	0,26	neutral	0,19	neutral	0,28	neutral	0,32	4	neutral	0	deleterious	1	neutral	-6	neutral	0,11	medium_impact	1,95	high_impact	1,87	low_impact	-2,21	0,7	0,85	NA	NA	N	0,33	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4552	4552	T	C	MI.12925	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	83	28	F	S	tTt/tCt	-7,11	0	0	benign	0,2	neutral	0,36	neutral	4,78	neutral	-0,02	neutral	-1,27	neutral_impact	-0,32	neutral	0,87	neutral	0,62	deleterious	2,27	17,94	0,06	0,35	disease	0,59	disease	0,57	disease	0,55	disease	0,61	2	neutral	0,57	deleterious	0,58	neutral	-6	neutral	0,42	medium_impact	-0,25	medium_impact	0,07	low_impact	-1,41	0,48	0,8	NA	NA	N	0,29	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4552	4552	T	A	MI.12926	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	83	28	F	Y	tTt/tAt	-7,11	0	0	benign	0,2	neutral	0,29	neutral	4,63	neutral	-0,96	neutral	-0,86	low_impact	1,02	neutral	0,91	neutral	0,58	deleterious	2,24	17,76	0,18	0,45	disease	0,7	disease	0,54	disease	0,52	disease	0,56	1	neutral	0,65	deleterious	0,55	neutral	-6	deleterious	0,44	medium_impact	-0,25	medium_impact	-0,01	medium_impact	-0,29	0,71	0,85	NA	NA	N	0,4	N	0,48	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4552	4552	T	G	MI.12927	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	83	28	F	C	tTt/tGt	-7,11	0	0	possibly_damaging	0,69	neutral	0,17	neutral	4,62	neutral	-2,35	neutral	-0,99	low_impact	0,91	neutral	0,83	neutral	0,44	deleterious	3,7	23,3	0,06	0,35	disease	0,8	disease	0,77	disease	0,54	disease	0,71	4	neutral	0,86	neutral	0,24	neutral	-3	deleterious	0,71	low_impact	-1,12	medium_impact	-0,17	medium_impact	-0,38	0,23	0,8	NA	NA	N	0,31	N	0,64	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4553	4553	T	G	MI.12928	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	84	28	F	L	ttT/ttG	0,72	0	0,01	benign	0	neutral	1	neutral	4,91	neutral	1,47	neutral	2,27	neutral_impact	-1,26	neutral	0,97	neutral	0,97	neutral	-0,59	0,13	0,16	0,45	neutral	0,26	neutral	0,19	neutral	0,28	neutral	0,32	4	neutral	0	deleterious	1	neutral	-6	neutral	0,11	medium_impact	1,95	high_impact	1,87	low_impact	-2,21	0,7	0,85	NA	NA	N	0,32	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4553	4553	T	A	MI.12929	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	84	28	F	L	ttT/ttA	0,72	0	0,01	benign	0	neutral	1	neutral	4,91	neutral	1,47	neutral	2,27	neutral_impact	-1,26	neutral	0,97	neutral	0,97	neutral	-0,46	0,28	0,16	0,45	neutral	0,26	neutral	0,19	neutral	0,28	neutral	0,32	4	neutral	0	deleterious	1	neutral	-6	neutral	0,11	medium_impact	1,95	high_impact	1,87	low_impact	-2,21	0,7	0,85	NA	NA	N	0,32	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9134	9134	A	G	MI.1293	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	608	203	E	G	gAa/gGa	9,38	1	0	probably_damaging	0,99	deleterious	0	neutral	3,49	deleterious	-4,01	deleterious	-6,22	high_impact	4,03	damaging	0,53	neutral	0,62	deleterious	4,14	23,8	0,3	0,65	NA	NA	disease	0,83	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,65	low_impact	-1,4	high_impact	2,36	0,4	0,9	48,67	8,97	N	0,5	N	0,71	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4554	4554	A	G	MI.12930	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	85	29	T	A	Acc/Gcc	-2,96	0	0	benign	0	neutral	0,61	neutral	4,73	neutral	1,41	neutral	-0,08	neutral_impact	-1,21	neutral	0,95	neutral	0,94	neutral	-1,39	0	0,18	0,45	neutral	0,21	neutral	0,1	neutral	0,28	neutral	0,23	6	neutral	0,39	deleterious	0,81	neutral	-6	neutral	0,1	medium_impact	1,95	medium_impact	0,32	low_impact	-2,16	0,39	0,8	4,61	10,18	N	0,42	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4554	4554	A	C	MI.12931	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	85	29	T	P	Acc/Ccc	-2,96	0	0	benign	0,24	neutral	0,2	neutral	4,61	neutral	-1,9	neutral	-2,14	medium_impact	2,08	neutral	0,76	neutral	0,37	deleterious	0,31	5,75	0,05	0,35	disease	0,64	disease	0,87	disease	0,66	disease	0,79	6	neutral	0,76	deleterious	0,48	neutral	-3	neutral	0,37	medium_impact	-0,34	medium_impact	-0,13	medium_impact	0,61	0,35	0,8	4,61	10,18	N	0,27	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4554	4554	A	T	MI.12932	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	85	29	T	S	Acc/Tcc	-2,96	0	0	benign	0,06	neutral	0,42	neutral	4,63	neutral	-0,38	neutral	-1,05	neutral_impact	0,32	neutral	0,9	neutral	0,84	deleterious	0,06	3,2	0,33	0,5	neutral	0,42	disease	0,51	neutral	0,49	neutral	0,5	0	neutral	0,54	deleterious	0,68	neutral	-6	neutral	0,18	medium_impact	0,3	medium_impact	0,13	medium_impact	-0,88	0,59	0,8	4,61	10,18	N	0,34	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4555	4555	C	T	MI.12933	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	86	29	T	I	aCc/aTc	1,18	0	0	benign	0	neutral	0,42	neutral	4,85	neutral	2,42	neutral	1,8	neutral_impact	0,27	neutral	0,92	neutral	0,98	neutral	-0,56	0,15	0,09	0,35	neutral	0,24	disease	0,67	neutral	0,34	neutral	0,22	6	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	0,13	medium_impact	-0,92	0,67	0,85	4,61	10,18	N	0,3	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4555	4555	C	A	MI.12934	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	86	29	T	N	aCc/aAc	1,18	0	0	benign	0,24	neutral	0,31	neutral	4,61	neutral	-1,6	neutral	-2,26	medium_impact	2,08	neutral	0,85	neutral	0,56	neutral	1,56	13,65	0,23	0,45	disease	0,6	disease	0,78	disease	0,53	disease	0,7	4	neutral	0,63	deleterious	0,54	neutral	-3	neutral	0,34	medium_impact	-0,34	medium_impact	0,02	medium_impact	0,61	0,65	0,8	4,61	10,18	N	0,29	N	0,47	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4555	4555	C	G	MI.12935	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	86	29	T	S	aCc/aGc	1,18	0	0	benign	0,06	neutral	0,42	neutral	4,63	neutral	-0,38	neutral	-1,05	neutral_impact	0,32	neutral	0,9	neutral	0,84	deleterious	0,29	5,57	0,33	0,5	neutral	0,42	disease	0,51	neutral	0,49	neutral	0,5	0	neutral	0,54	deleterious	0,68	neutral	-6	neutral	0,18	medium_impact	0,3	medium_impact	0,13	medium_impact	-0,88	0,59	0,8	4,61	10,18	N	0,36	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4557	4557	T	G	MI.12936	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	88	30	W	G	Tga/Gga	-2,96	0	0	probably_damaging	1	neutral	0,28	neutral	4,49	deleterious	-5,47	deleterious	-11,92	high_impact	4	damaging	0,58	damaging	0,06	deleterious	3,77	23,4	0,03	0,35	disease	0,52	disease	0,86	disease	0,8	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	-0,02	high_impact	2,22	0,11	0,8	NA	NA	N	0,45	N	0,96	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4557	4557	T	C	MI.12937	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	88	30	W	R	Tga/Cga	-2,96	0	0	probably_damaging	1	neutral	0,17	neutral	4,49	deleterious	-5,33	deleterious	-12,83	high_impact	4	neutral	0,6	damaging	0,06	deleterious	3,39	23	0,02	0,35	neutral	0,37	disease	0,92	disease	0,83	disease	0,73	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,17	high_impact	2,22	0,14	0,8	NA	NA	N	0,45	N	0,97	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4558	4558	G	C	MI.12938	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	89	30	W	S	tGa/tCa	7,4	1	0	probably_damaging	1	neutral	0,32	neutral	4,5	deleterious	-4,16	deleterious	-12,83	high_impact	4	damaging	0,51	damaging	0,06	deleterious	3,87	23,5	0,02	0,35	neutral	0,41	disease	0,91	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,03	high_impact	2,22	0,11	0,8	NA	NA	P	0,61	P	0,94	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4558	4558	G	T	MI.12939	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	89	30	W	L	tGa/tTa	7,4	1	0	probably_damaging	1	neutral	0,63	neutral	4,64	neutral	-1,9	deleterious	-11,92	high_impact	3,65	damaging	0,59	damaging	0,05	deleterious	4,14	23,8	0,03	0,35	neutral	0,44	disease	0,87	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	0,34	medium_impact	1,93	0,12	0,8	NA	NA	P	0,6	P	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9134	9134	A	T	MI.1294	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	608	203	E	V	gAa/gTa	9,38	1	0	probably_damaging	1	deleterious	0	neutral	3,38	deleterious	-5,4	deleterious	-6,22	high_impact	4,58	damaging	0,47	neutral	0,48	deleterious	4,1	23,7	0,2	0,65	NA	NA	disease	0,9	disease	0,78	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,6	low_impact	-1,4	high_impact	2,83	0,48	0,9	48,67	8,97	P	0,59	P	0,86	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4559	4559	A	T	MI.12940	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	90	30	W	C	tgA/tgT	9,01	1	0	probably_damaging	1	neutral	0,1	neutral	4,51	deleterious	-4,91	deleterious	-11,92	high_impact	4	neutral	0,61	damaging	0,05	deleterious	3,97	23,6	0,03	0,35	neutral	0,27	disease	0,91	disease	0,8	disease	0,7	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,76	low_impact	-3,54	medium_impact	-0,32	high_impact	2,22	0,16	0,8	NA	NA	P	0,58	P	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4559	4559	A	C	MI.12941	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	90	30	W	C	tgA/tgC	9,01	1	0	probably_damaging	1	neutral	0,1	neutral	4,51	deleterious	-4,91	deleterious	-11,92	high_impact	4	neutral	0,61	damaging	0,05	deleterious	3,84	23,4	0,03	0,35	neutral	0,27	disease	0,91	disease	0,8	disease	0,7	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,76	low_impact	-3,54	medium_impact	-0,32	high_impact	2,22	0,16	0,8	NA	NA	P	0,57	P	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4560	4560	G	A	MI.12942	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	91	31	V	M	Gta/Ata	2,1	0,94	0	benign	0,02	neutral	1	neutral	4,59	neutral	-0,48	neutral	-0,84	neutral_impact	-0,42	neutral	0,89	neutral	0,94	neutral	-0,68	0,08	0,17	0,45	neutral	0,32	neutral	0,13	neutral	0,21	neutral	0,24	5	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,14	medium_impact	0,75	high_impact	1,87	low_impact	-1,5	0,89	0,9	3,46	8,29	N	0,35	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4560	4560	G	T	MI.12943	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	91	31	V	L	Gta/Tta	2,1	0,94	0	benign	0	neutral	0,79	neutral	4,83	neutral	1,08	neutral	-0,78	neutral_impact	-0,04	neutral	0,93	neutral	0,9	deleterious	0,41	6,7	0,13	0,4	neutral	0,23	disease	0,53	neutral	0,31	neutral	0,22	6	neutral	0,2	deleterious	0,9	neutral	-6	neutral	0,13	medium_impact	1,95	medium_impact	0,53	low_impact	-1,18	0,58	0,8	3,46	8,29	N	0,3	N	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4560	4560	G	C	MI.12944	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	91	31	V	L	Gta/Cta	2,1	0,94	0	benign	0	neutral	0,79	neutral	4,83	neutral	1,08	neutral	-0,78	neutral_impact	-0,04	neutral	0,93	neutral	0,9	deleterious	0,26	5,32	0,13	0,4	neutral	0,23	disease	0,53	neutral	0,31	neutral	0,22	6	neutral	0,2	deleterious	0,9	neutral	-6	neutral	0,13	medium_impact	1,95	medium_impact	0,53	low_impact	-1,18	0,58	0,8	3,46	8,29	N	0,3	N	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4561	4561	T	G	MI.12945	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	92	31	V	G	gTa/gGa	0,03	0	0,01	benign	0,14	neutral	0,52	neutral	4,48	deleterious	-3,29	deleterious	-4,96	medium_impact	2,21	neutral	0,87	neutral	0,53	deleterious	3,32	22,9	0,02	0,35	disease	0,64	disease	0,63	disease	0,59	disease	0,71	4	neutral	0,39	deleterious	0,69	neutral	-3	neutral	0,35	medium_impact	-0,08	medium_impact	0,23	medium_impact	0,72	0,27	0,8	3,46	8,29	N	0,31	N	0,76	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4561	4561	T	C	MI.12946	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	92	31	V	A	gTa/gCa	0,03	0	0,01	benign	0	neutral	0,52	neutral	4,52	neutral	-1,54	neutral	-2,24	neutral_impact	0,38	neutral	0,95	neutral	0,95	deleterious	0,22	4,94	0,08	0,35	neutral	0,38	neutral	0,3	neutral	0,39	neutral	0,44	1	neutral	0,47	deleterious	0,76	neutral	-6	neutral	0,14	medium_impact	1,95	medium_impact	0,23	medium_impact	-0,83	0,33	0,8	3,46	8,29	N	0,3	N	0,4	polymorphism	1	0,05	rs41376350	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4561	4561	T	A	MI.12947	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	92	31	V	E	gTa/gAa	0,03	0	0,01	benign	0,34	neutral	0,34	neutral	4,47	deleterious	-3,54	deleterious	-4,3	medium_impact	2,56	neutral	0,9	neutral	0,51	deleterious	4,58	24,4	0,02	0,35	disease	0,57	disease	0,82	disease	0,69	disease	0,77	5	neutral	0,59	deleterious	0,5	neutral	-3	deleterious	0,56	medium_impact	-0,53	medium_impact	0,05	medium_impact	1,01	0,26	0,8	3,46	8,29	N	0,37	N	0,82	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4563	4563	G	A	MI.12948	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	94	32	G	S	Ggc/Agc	-5,27	0	0	probably_damaging	1	neutral	0,4	neutral	4,47	neutral	-1,82	deleterious	-5,54	medium_impact	2,38	damaging	0,38	damaging	0,02	deleterious	4,01	23,6	0,05	0,35	neutral	0,5	disease	0,84	disease	0,59	disease	0,68	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,11	medium_impact	0,86	0,62	0,8	NA	NA	N	0,5	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4563	4563	G	C	MI.12949	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	94	32	G	R	Ggc/Cgc	-5,27	0	0	probably_damaging	1	neutral	0,35	neutral	4,35	deleterious	-3,81	deleterious	-7,39	medium_impact	3,4	damaging	0,46	damaging	0,02	deleterious	3,74	23,3	0,02	0,35	neutral	0,43	disease	0,92	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0,06	medium_impact	1,72	0,34	0,8	NA	NA	N	0,38	N	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9135	9135	A	C	MI.1295	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	609	203	E	D	gaA/gaC	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	3,52	deleterious	-3,76	deleterious	-2,67	high_impact	4,58	damaging	0,55	neutral	0,54	deleterious	3,83	23,4	0,44	0,65	NA	NA	disease	0,79	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,65	low_impact	-1,4	high_impact	2,83	0,62	0,9	48,67	8,97	P	0,58	P	0,87	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4563	4563	G	T	MI.12950	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	94	32	G	C	Ggc/Tgc	-5,27	0	0	probably_damaging	1	neutral	0,18	neutral	4,33	deleterious	-4,38	deleterious	-8,31	medium_impact	2,56	damaging	0,48	damaging	0,02	deleterious	3,93	23,5	0,03	0,35	disease	0,88	disease	0,92	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,16	medium_impact	1,01	0,23	0,8	NA	NA	N	0,3	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4564	4564	G	T	MI.12951	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	95	32	G	V	gGc/gTc	6,01	1	0	probably_damaging	1	neutral	0,5	neutral	4,41	neutral	-1,99	deleterious	-8,31	medium_impact	3,4	damaging	0,44	damaging	0,02	deleterious	3,59	23,2	0,03	0,35	disease	0,64	disease	0,9	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	0,21	medium_impact	1,72	0,23	0,8	NA	NA	P	0,62	P	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4564	4564	G	A	MI.12952	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	95	32	G	D	gGc/gAc	6,01	1	0	probably_damaging	1	neutral	0,2	neutral	4,33	deleterious	-4,53	deleterious	-6,46	high_impact	3,94	damaging	0,49	damaging	0,02	deleterious	3,74	23,3	0,02	0,35	neutral	0,3	disease	0,9	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	-0,13	high_impact	2,17	0,2	0,8	NA	NA	P	0,59	P	0,95	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4564	4564	G	C	MI.12953	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	95	32	G	A	gGc/gCc	6,01	1	0	probably_damaging	1	neutral	0,51	neutral	4,44	neutral	-0,5	deleterious	-5,54	medium_impact	2,5	damaging	0,44	damaging	0,04	deleterious	2,96	22,1	0,09	0,35	neutral	0,5	disease	0,78	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,22	medium_impact	0,96	0,44	0,8	NA	NA	P	0,59	P	0,74	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4566	4566	C	A	MI.12954	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	97	33	L	M	Cta/Ata	-15,63	0	0	probably_damaging	1	neutral	0,22	neutral	4,43	neutral	-2,06	neutral	-0,88	low_impact	1,5	neutral	0,81	damaging	0,22	deleterious	3,58	23,2	0,13	0,4	neutral	0,28	disease	0,59	disease	0,58	disease	0,62	2	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	-0,1	medium_impact	0,12	0,61	0,8	0,86	12,13	N	0,3	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4566	4566	C	G	MI.12955	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	97	33	L	V	Cta/Gta	-15,63	0	0	probably_damaging	1	neutral	0,43	neutral	4,44	neutral	-1,86	neutral	-1,8	medium_impact	2,58	neutral	0,89	damaging	0,25	deleterious	3,26	22,8	0,09	0,35	neutral	0,44	disease	0,69	disease	0,6	disease	0,63	3	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,14	medium_impact	1,03	0,59	0,8	0,86	12,13	N	0,29	N	0,43	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4567	4567	T	C	MI.12956	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	98	33	L	P	cTa/cCa	-0,43	0	0	probably_damaging	1	neutral	0,15	neutral	4,37	deleterious	-4,74	deleterious	-5,01	medium_impact	3,13	neutral	0,79	damaging	0,17	deleterious	3,75	23,3	0,02	0,35	disease	0,76	disease	0,85	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,21	medium_impact	1,49	0,29	0,8	0,86	12,13	N	0,28	N	0,95	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4567	4567	T	G	MI.12957	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	98	33	L	R	cTa/cGa	-0,43	0	0	probably_damaging	1	neutral	0,26	neutral	4,37	deleterious	-4,18	deleterious	-4,08	medium_impact	3,48	neutral	0,78	damaging	0,16	deleterious	4,02	23,6	0,02	0,35	disease	0,65	disease	0,92	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,87	low_impact	-3,54	medium_impact	-0,04	medium_impact	1,79	0,28	0,8	0,86	12,13	N	0,32	N	0,96	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4567	4567	T	A	MI.12958	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	98	33	L	Q	cTa/cAa	-0,43	0	0	probably_damaging	1	neutral	0,23	neutral	4,37	deleterious	-4,31	deleterious	-4,08	medium_impact	3,48	neutral	0,79	damaging	0,21	deleterious	3,92	23,5	0,02	0,35	neutral	0,23	disease	0,83	disease	0,6	disease	0,66	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	-0,08	medium_impact	1,79	0,34	0,8	0,86	12,13	N	0,31	N	0,96	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4569	4569	G	A	MI.12959	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	100	34	E	K	Gaa/Aaa	-1,12	0	0	probably_damaging	1	neutral	0,29	neutral	3,14	deleterious	-6,47	deleterious	-3,69	high_impact	3,66	neutral	0,62	damaging	0,06	deleterious	4,32	24	0,02	0,35	disease	0,84	disease	0,91	disease	0,85	disease	0,72	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,9	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,94	0,58	0,8	0,29	6,56	N	0,45	N	0,98	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9135	9135	A	T	MI.1296	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	609	203	E	D	gaA/gaT	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	3,52	deleterious	-3,76	deleterious	-2,67	high_impact	4,58	damaging	0,55	neutral	0,54	deleterious	3,98	23,6	0,44	0,65	NA	NA	disease	0,79	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,65	low_impact	-1,4	high_impact	2,83	0,62	0,9	48,67	8,97	P	0,58	P	0,87	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4569	4569	G	C	MI.12960	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	100	34	E	Q	Gaa/Caa	-1,12	0	0	probably_damaging	1	neutral	0,3	neutral	3,14	deleterious	-6,46	deleterious	-2,77	high_impact	4	neutral	0,67	damaging	0,07	deleterious	3,15	22,6	0,05	0,35	disease	0,86	disease	0,8	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	0	high_impact	2,22	0,56	0,8	0,29	6,56	N	0,4	N	0,88	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4570	4570	A	G	MI.12961	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	101	34	E	G	gAa/gGa	6,01	1	0	probably_damaging	1	neutral	0,34	neutral	3,18	deleterious	-5,24	deleterious	-6,46	high_impact	4	neutral	0,64	damaging	0,1	deleterious	3,88	23,5	0,02	0,35	disease	0,86	disease	0,81	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,05	high_impact	2,22	0,13	0,8	0,29	6,56	P	0,69	P	0,45	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4570	4570	A	T	MI.12962	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	101	34	E	V	gAa/gTa	6,01	1	0	probably_damaging	1	neutral	0,51	neutral	3,12	deleterious	-8,28	deleterious	-6,46	high_impact	3,66	neutral	0,68	damaging	0,08	deleterious	3,84	23,4	0,02	0,35	disease	0,92	disease	0,91	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	0,22	medium_impact	1,94	0,23	0,8	0,29	6,56	P	0,64	P	0,81	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4570	4570	A	C	MI.12963	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	101	34	E	A	gAa/gCa	6,01	1	0	probably_damaging	1	neutral	0,51	neutral	3,14	deleterious	-6,58	deleterious	-5,54	high_impact	3,66	neutral	0,69	damaging	0,12	deleterious	3,35	22,9	0,02	0,35	neutral	0,42	disease	0,83	disease	0,77	disease	0,71	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	0,22	medium_impact	1,94	0,28	0,8	0,29	6,56	P	0,57	P	0,73	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4571	4571	A	C	MI.12964	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	102	34	E	D	gaA/gaC	8,55	1	0	probably_damaging	1	neutral	0,21	neutral	3,28	deleterious	-3,93	deleterious	-2,77	high_impact	3,66	neutral	0,68	damaging	0,06	deleterious	3,56	23,1	0,07	0,35	disease	0,75	disease	0,77	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,11	medium_impact	1,94	0,51	0,8	0,29	6,56	P	0,66	P	0,85	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4571	4571	A	T	MI.12965	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	102	34	E	D	gaA/gaT	8,55	1	0	probably_damaging	1	neutral	0,21	neutral	3,28	deleterious	-3,93	deleterious	-2,77	high_impact	3,66	neutral	0,68	damaging	0,06	deleterious	3,71	23,3	0,07	0,35	disease	0,75	disease	0,77	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,11	medium_impact	1,94	0,51	0,8	0,29	6,56	P	0,68	P	0,85	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4572	4572	A	C	MI.12966	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	103	35	M	L	Ata/Cta	3,25	1	0	benign	0,02	neutral	1	neutral	4,85	neutral	2,15	neutral	-1,96	neutral_impact	0,18	neutral	0,89	neutral	0,83	neutral	1,74	14,62	0,24	0,45	neutral	0,29	disease	0,76	neutral	0,34	neutral	0,23	5	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,21	medium_impact	0,75	high_impact	1,87	medium_impact	-0,99	0,6	0,8	0,86	7,41	N	0,41	N	0,6	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4572	4572	A	T	MI.12967	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	103	35	M	L	Ata/Tta	3,25	1	0	benign	0,02	neutral	1	neutral	4,85	neutral	2,15	neutral	-1,96	neutral_impact	0,18	neutral	0,89	neutral	0,83	deleterious	1,8	15	0,24	0,45	neutral	0,29	disease	0,76	neutral	0,34	neutral	0,23	5	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,21	medium_impact	0,75	high_impact	1,87	medium_impact	-0,99	0,6	0,8	0,86	7,41	N	0,42	N	0,6	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4572	4572	A	G	MI.12968	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	103	35	M	V	Ata/Gta	3,25	1	0	benign	0,28	neutral	0,54	neutral	4,81	neutral	1,07	deleterious	-2,77	low_impact	1,44	neutral	0,93	neutral	0,37	deleterious	2,32	18,33	0,21	0,45	neutral	0,2	disease	0,84	disease	0,51	neutral	0,22	6	neutral	0,36	deleterious	0,63	neutral	-6	deleterious	0,46	medium_impact	-0,42	medium_impact	0,25	medium_impact	0,07	0,54	0,8	0,86	7,41	N	0,35	N	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4573	4573	T	C	MI.12969	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	104	35	M	T	aTa/aCa	1,41	1	0	possibly_damaging	0,74	neutral	0,41	neutral	4,68	neutral	-0,39	deleterious	-4,86	medium_impact	2,31	neutral	0,81	damaging	0,15	deleterious	2,86	21,6	0,07	0,35	neutral	0,37	disease	0,85	disease	0,61	disease	0,74	5	neutral	0,74	neutral	0,34	NA	0	deleterious	0,71	low_impact	-1,21	medium_impact	0,12	medium_impact	0,8	0,15	0,8	0,86	7,41	N	0,36	N	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9136	9136	A	G	MI.1297	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	610	204	I	V	Atc/Gtc	-0,33	0	0	benign	0	neutral	1	neutral	4,27	neutral	-0,78	neutral	-0,45	neutral_impact	0,16	neutral	0,81	neutral	0,79	neutral	-1,59	0	0,62	0,7	NA	NA	neutral	0,11	neutral	0,28	neutral	0,22	6	neutral	0	deleterious	1	neutral	-6	neutral	0,14	high_impact	2,09	high_impact	1,98	medium_impact	-0,96	0,31	0,9	27,88	21,96	N	0,27	N	0,44	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4573	4573	T	A	MI.12970	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	104	35	M	K	aTa/aAa	1,41	1	0	possibly_damaging	0,74	neutral	0,27	neutral	4,63	neutral	-2,44	deleterious	-5,17	medium_impact	2,86	neutral	0,83	damaging	0,13	deleterious	3,93	23,5	0,02	0,35	disease	0,64	disease	0,94	disease	0,67	disease	0,81	6	neutral	0,81	neutral	0,27	NA	0	deleterious	0,8	low_impact	-1,21	medium_impact	-0,03	medium_impact	1,26	0,15	0,8	0,86	7,41	N	0,45	N	0,89	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4574	4574	A	T	MI.12971	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	105	35	M	I	atA/atT	7,4	1	0	benign	0,39	neutral	0,92	neutral	4,71	neutral	1,08	deleterious	-2,59	neutral_impact	-0,36	neutral	0,89	neutral	0,89	neutral	1,4	12,81	0,21	0,45	neutral	0,23	neutral	0,34	neutral	0,23	neutral	0,44	1	neutral	0,31	deleterious	0,77	neutral	-6	deleterious	0,51	medium_impact	-0,62	medium_impact	0,8	low_impact	-1,45	0,58	0,8	0,86	7,41	N	0,55	P	0,4	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4574	4574	A	C	MI.12972	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	105	35	M	I	atA/atC	7,4	1	0	benign	0,39	neutral	0,92	neutral	4,71	neutral	1,08	deleterious	-2,59	neutral_impact	-0,36	neutral	0,89	neutral	0,89	neutral	1,33	12,41	0,21	0,45	neutral	0,23	neutral	0,34	neutral	0,23	neutral	0,44	1	neutral	0,31	deleterious	0,77	neutral	-6	deleterious	0,51	medium_impact	-0,62	medium_impact	0,8	low_impact	-1,45	0,58	0,8	0,86	7,41	N	0,54	P	0,4	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4575	4575	A	G	MI.12973	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	106	36	N	D	Aac/Gac	-3,65	0	0	probably_damaging	1	neutral	0,24	neutral	4,6	neutral	-1,24	deleterious	-4,49	high_impact	3,63	neutral	0,83	neutral	0,45	deleterious	3,68	23,3	0,25	0,45	disease	0,75	disease	0,8	disease	0,76	disease	0,72	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	-0,07	medium_impact	1,91	0,2	0,8	1,15	8,05	N	0,4	N	0,7	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4575	4575	A	C	MI.12974	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	106	36	N	H	Aac/Cac	-3,65	0	0	probably_damaging	1	neutral	0,55	neutral	4,59	neutral	-1,9	deleterious	-4,52	high_impact	3,98	neutral	0,87	neutral	0,32	deleterious	2,92	21,9	0,17	0,45	disease	0,74	disease	0,86	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,26	high_impact	2,21	0,2	0,8	1,15	8,05	N	0,34	N	0,49	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4575	4575	A	T	MI.12975	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	106	36	N	Y	Aac/Tac	-3,65	0	0	probably_damaging	1	neutral	1	neutral	4,59	neutral	-1,81	deleterious	-7,22	high_impact	3,98	neutral	0,83	neutral	0,37	deleterious	3,52	23,1	0,04	0,35	disease	0,64	disease	0,9	disease	0,71	disease	0,73	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,83	low_impact	-3,54	high_impact	1,87	high_impact	2,21	0,14	0,8	1,15	8,05	N	0,28	N	0,91	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4576	4576	A	T	MI.12976	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	107	36	N	I	aAc/aTc	6,71	0,94	0	probably_damaging	1	neutral	0,43	neutral	4,62	neutral	-0,62	deleterious	-8,11	high_impact	3,98	neutral	0,87	neutral	0,54	deleterious	3,66	23,2	0,05	0,35	neutral	0,25	disease	0,94	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,76	low_impact	-3,54	medium_impact	0,14	high_impact	2,21	0,11	0,8	1,15	8,05	P	0,59	P	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4576	4576	A	G	MI.12977	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	107	36	N	S	aAc/aGc	6,71	0,94	0	probably_damaging	1	neutral	0,45	neutral	4,81	neutral	1,75	deleterious	-4,35	medium_impact	2,34	neutral	0,9	neutral	0,81	neutral	1,66	14,2	0,37	0,5	neutral	0,4	disease	0,78	neutral	0,47	neutral	0,21	6	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,16	medium_impact	0,83	0,21	0,8	1,15	8,05	P	0,53	P	0,22	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4576	4576	A	C	MI.12978	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	107	36	N	T	aAc/aCc	6,71	0,94	0	probably_damaging	1	neutral	0,43	neutral	4,62	neutral	-0,42	deleterious	-5,34	medium_impact	3,29	neutral	0,84	neutral	0,49	deleterious	3,22	22,7	0,18	0,45	neutral	0,49	disease	0,84	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	0,14	medium_impact	1,63	0,22	0,8	1,15	8,05	P	0,54	P	0,58	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4577	4577	C	A	MI.12979	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	108	36	N	K	aaC/aaA	1,41	0,67	0,01	probably_damaging	1	neutral	0,34	neutral	4,63	neutral	-0,39	deleterious	-5,38	high_impact	3,98	neutral	0,85	neutral	0,36	deleterious	4,32	24	0,16	0,45	disease	0,62	disease	0,89	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	0,05	high_impact	2,21	0,33	0,8	1,15	8,05	N	0,38	N	0,83	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9136	9136	A	T	MI.1298	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	610	204	I	F	Atc/Ttc	-0,33	0	0	benign	0,39	neutral	0,46	neutral	4,18	neutral	-1,6	neutral	-0,56	low_impact	0,9	neutral	0,86	neutral	0,95	neutral	1,1	11,19	0,44	0,65	NA	NA	disease	0,6	neutral	0,34	neutral	0,46	1	neutral	0,48	deleterious	0,54	neutral	-6	deleterious	0,62	medium_impact	-0,57	medium_impact	0,25	medium_impact	-0,33	0,56	0,9	27,88	21,96	N	0,31	N	0,19	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4577	4577	C	G	MI.12980	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	108	36	N	K	aaC/aaG	1,41	0,67	0,01	probably_damaging	1	neutral	0,34	neutral	4,63	neutral	-0,39	deleterious	-5,38	high_impact	3,98	neutral	0,85	neutral	0,36	deleterious	3,82	23,4	0,16	0,45	disease	0,62	disease	0,89	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	0,05	high_impact	2,21	0,33	0,8	1,15	8,05	N	0,38	N	0,83	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4578	4578	A	C	MI.12981	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	109	37	M	L	Atg/Ctg	-2,73	0	0	benign	0,24	neutral	0,94	neutral	4,98	neutral	2,45	neutral	-2,04	neutral_impact	-0,21	neutral	0,91	neutral	0,89	neutral	1,59	13,8	0,29	0,45	neutral	0,23	disease	0,77	neutral	0,4	neutral	0,21	6	neutral	0,15	deleterious	0,85	neutral	-6	deleterious	0,45	medium_impact	-0,34	medium_impact	0,87	low_impact	-1,32	0,24	0,8	0,86	7,47	N	0,28	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4578	4578	A	T	MI.12982	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	109	37	M	L	Atg/Ttg	-2,73	0	0	benign	0,24	neutral	0,94	neutral	4,98	neutral	2,45	neutral	-2,04	neutral_impact	-0,21	neutral	0,91	neutral	0,89	neutral	1,6	13,87	0,29	0,45	neutral	0,23	disease	0,77	neutral	0,4	neutral	0,21	6	neutral	0,15	deleterious	0,85	neutral	-6	deleterious	0,45	medium_impact	-0,34	medium_impact	0,87	low_impact	-1,32	0,24	0,8	0,86	7,47	N	0,29	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4578	4578	A	G	MI.12983	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	109	37	M	V	Atg/Gtg	-2,73	0	0	benign	0,34	neutral	0,66	neutral	4,74	neutral	1,16	deleterious	-3,14	medium_impact	2,31	neutral	0,82	neutral	0,53	deleterious	2,4	18,82	0,21	0,45	neutral	0,27	disease	0,82	disease	0,62	disease	0,73	5	neutral	0,28	deleterious	0,66	neutral	-3	deleterious	0,5	medium_impact	-0,53	medium_impact	0,37	medium_impact	0,8	0,26	0,8	0,86	7,47	N	0,25	N	0,65	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4579	4579	T	A	MI.12984	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	110	37	M	K	aTg/aAg	1,87	0,54	0	possibly_damaging	0,54	neutral	0,32	neutral	4,58	neutral	-1,96	deleterious	-5,08	medium_impact	2,31	neutral	0,82	neutral	0,36	deleterious	3,92	23,5	0,03	0,35	disease	0,65	disease	0,92	disease	0,71	disease	0,76	5	neutral	0,67	neutral	0,39	NA	0	deleterious	0,76	medium_impact	-0,86	medium_impact	0,03	medium_impact	0,8	0,12	0,8	0,86	7,47	N	0,33	N	0,87	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4579	4579	T	C	MI.12985	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	110	37	M	T	aTg/aCg	1,87	0,54	0	benign	0,04	neutral	1	neutral	4,65	neutral	0,14	deleterious	-4,73	neutral_impact	-0,78	neutral	0,86	neutral	0,9	neutral	0,96	10,43	0,1	0,4	neutral	0,25	neutral	0,21	neutral	0,32	neutral	0,33	3	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,19	medium_impact	0,47	high_impact	1,87	low_impact	-1,8	0,14	0,8	0,86	7,47	N	0,25	N	0,35	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4580	4580	G	C	MI.12986	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	111	37	M	I	atG/atC	3,48	0,59	0,12	benign	0,42	neutral	0,61	neutral	4,78	neutral	1,41	deleterious	-3,05	low_impact	1,62	neutral	0,83	neutral	0,42	deleterious	3,36	22,9	0,21	0,45	neutral	0,37	disease	0,84	disease	0,6	disease	0,75	5	neutral	0,37	deleterious	0,6	neutral	-6	deleterious	0,63	medium_impact	-0,67	medium_impact	0,32	medium_impact	0,22	0,31	0,8	0,86	7,47	N	0,28	N	0,72	disease_causing	1	0,06	rs28357975	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4580	4580	G	T	MI.12987	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	111	37	M	I	atG/atT	3,48	0,59	0,12	benign	0,42	neutral	0,61	neutral	4,78	neutral	1,41	deleterious	-3,05	low_impact	1,62	neutral	0,83	neutral	0,42	deleterious	3,48	23,1	0,21	0,45	neutral	0,37	disease	0,84	disease	0,6	disease	0,75	5	neutral	0,37	deleterious	0,6	neutral	-6	deleterious	0,63	medium_impact	-0,67	medium_impact	0,32	medium_impact	0,22	0,31	0,8	0,86	7,47	N	0,28	N	0,72	disease_causing	1	0,06	rs28357975	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4581	4581	C	G	MI.12988	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	112	38	L	V	Cta/Gta	-3,65	0	0	probably_damaging	1	neutral	0,07	neutral	4,62	neutral	-1,84	neutral	-2,42	medium_impact	3,06	neutral	0,87	damaging	0,14	deleterious	3,25	22,8	0,08	0,35	disease	0,51	disease	0,71	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,42	medium_impact	1,43	0,55	0,8	0,58	7,04	N	0,36	N	0,77	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4581	4581	C	A	MI.12989	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	112	38	L	M	Cta/Ata	-3,65	0	0	probably_damaging	1	neutral	0,16	neutral	4,55	deleterious	-3,63	neutral	-1,39	low_impact	1	neutral	0,92	neutral	0,88	deleterious	2,39	18,73	0,1	0,4	disease	0,6	disease	0,59	neutral	0,33	neutral	0,24	5	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,77	low_impact	-3,54	medium_impact	-0,19	medium_impact	-0,3	0,49	0,8	0,58	7,04	N	0,43	N	0,88	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9136	9136	A	C	MI.1299	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	610	204	I	L	Atc/Ctc	-0,33	0	0	benign	0,03	neutral	0,37	neutral	4,45	neutral	0,26	neutral	-0,65	neutral_impact	0,41	neutral	0,89	neutral	0,91	deleterious	0,13	3,93	0,42	0,65	NA	NA	neutral	0,43	neutral	0,24	neutral	0,2	6	neutral	0,61	deleterious	0,67	neutral	-6	neutral	0,23	medium_impact	0,68	medium_impact	0,16	medium_impact	-0,75	0,51	0,9	27,88	21,96	N	0,38	N	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4582	4582	T	C	MI.12990	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	113	38	L	P	cTa/cCa	-1,58	0	0	probably_damaging	1	deleterious	0,02	neutral	4,66	deleterious	-4,81	deleterious	-5,96	medium_impact	3,27	neutral	0,88	damaging	0,09	deleterious	3,76	23,3	0,01	0,35	disease	0,73	disease	0,87	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,89	low_impact	-3,54	medium_impact	-0,73	medium_impact	1,61	0,13	0,8	0,58	7,04	N	0,4	N	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4582	4582	T	A	MI.12991	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	113	38	L	Q	cTa/cAa	-1,58	0	0	probably_damaging	1	deleterious	0,03	neutral	4,5	deleterious	-5,11	deleterious	-5	high_impact	3,62	neutral	0,89	damaging	0,13	deleterious	4	23,6	0,01	0,35	disease	0,54	disease	0,87	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-3,54	medium_impact	-0,63	medium_impact	1,9	0,19	0,8	0,58	7,04	N	0,41	N	0,99	polymorphism	1	0,3	rs28393930	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4582	4582	T	G	MI.12992	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	113	38	L	R	cTa/cGa	-1,58	0	0	probably_damaging	1	deleterious	0,04	neutral	4,5	deleterious	-4,93	deleterious	-5,04	high_impact	3,62	neutral	0,86	damaging	0,09	deleterious	4,04	23,7	0,01	0,35	disease	0,55	disease	0,92	disease	0,78	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,89	low_impact	-3,54	medium_impact	-0,56	medium_impact	1,9	0,08	0,8	0,58	7,04	N	0,39	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4584	4584	G	C	MI.12993	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	115	39	A	P	Gct/Cct	-4,35	0	0	probably_damaging	1	neutral	0,22	neutral	4,55	neutral	-2,86	deleterious	-4,2	medium_impact	3	neutral	0,82	damaging	0,11	deleterious	3,64	23,2	0,03	0,35	disease	0,73	disease	0,87	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,88	low_impact	-3,54	medium_impact	-0,1	medium_impact	1,38	0,58	0,8	0,29	6,69	N	0,3	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4584	4584	G	A	MI.12994	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	115	39	A	T	Gct/Act	-4,35	0	0	probably_damaging	1	neutral	0,41	neutral	4,68	neutral	0,43	deleterious	-2,94	medium_impact	2,64	neutral	0,9	neutral	0,57	deleterious	4	23,6	0,1	0,4	neutral	0,46	disease	0,81	disease	0,53	disease	0,54	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,12	medium_impact	1,08	0,77	0,85	0,29	6,69	N	0,41	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4584	4584	G	T	MI.12995	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	115	39	A	S	Gct/Tct	-4,35	0	0	probably_damaging	1	neutral	0,54	neutral	4,88	neutral	1,74	neutral	-2,15	low_impact	0,98	neutral	0,92	neutral	0,34	deleterious	3,48	23,1	0,23	0,45	neutral	0,4	disease	0,77	neutral	0,36	neutral	0,19	6	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,8	low_impact	-3,54	medium_impact	0,25	medium_impact	-0,32	0,54	0,8	0,29	6,69	N	0,3	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4585	4585	C	A	MI.12996	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	116	39	A	D	gCt/gAt	2,56	0,98	0	probably_damaging	1	neutral	0,2	neutral	4,54	deleterious	-3,17	deleterious	-4,94	medium_impact	3,13	neutral	0,89	damaging	0,1	deleterious	4,42	24,2	0,01	0,35	disease	0,61	disease	0,9	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	-0,13	medium_impact	1,49	0,31	0,8	0,29	6,69	P	0,59	P	0,95	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4585	4585	C	T	MI.12997	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	116	39	A	V	gCt/gTt	2,56	0,98	0	probably_damaging	1	neutral	0,53	neutral	4,66	neutral	0,22	deleterious	-3,41	medium_impact	2,64	neutral	0,85	damaging	0,12	deleterious	4,25	23,9	0,06	0,35	neutral	0,48	disease	0,85	disease	0,64	disease	0,7	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	0,24	medium_impact	1,08	0,77	0,85	0,29	6,69	N	0,4	N	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4585	4585	C	G	MI.12998	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	116	39	A	G	gCt/gGt	2,56	0,98	0	probably_damaging	1	neutral	0,36	neutral	4,55	neutral	-2,33	deleterious	-3,39	low_impact	1,9	neutral	0,9	damaging	0,13	deleterious	3,79	23,4	0,19	0,45	disease	0,65	disease	0,76	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,81	low_impact	-3,54	medium_impact	0,07	medium_impact	0,46	0,68	0,85	0,29	6,69	N	0,53	P	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4587	4587	T	C	MI.12999	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	118	40	F	L	Ttt/Ctt	-10,56	0	0	benign	0,43	neutral	0,4	neutral	4,68	neutral	0,17	neutral	0,75	low_impact	1,43	neutral	0,9	neutral	0,52	deleterious	3,79	23,4	0,19	0,45	neutral	0,28	disease	0,6	neutral	0,25	neutral	0,21	6	neutral	0,55	deleterious	0,49	neutral	-6	deleterious	0,51	medium_impact	-0,69	medium_impact	0,11	medium_impact	0,06	0,66	0,8	NA	NA	N	0,37	N	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8532	8532	C	G	MI.13	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	6	2	N	K	aaC/aaG	1,75	0,87	0	probably_damaging	0,97	neutral	0,07	neutral	4,69	neutral	0,02	deleterious	-3,41	medium_impact	2,6	neutral	0,87	neutral	0,44	deleterious	6,13	28,4	0,78	0,8	disease	0,51	neutral	0,42	neutral	0,25	neutral	0,38	3	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,68	low_impact	-2,19	medium_impact	-0,34	medium_impact	1,13	0,26	0,9	41,59	7,23	N	0,39	N	1	disease_causing	0,89	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8587	8587	G	A	MI.130	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	61	21	V	M	Gta/Ata	-8,2	0	0	possibly_damaging	0,88	neutral	0,28	neutral	4,25	neutral	-2,02	neutral	-0,88	neutral_impact	0,11	neutral	0,92	neutral	0,9	deleterious	2,08	16,74	0,39	0,65	disease	0,65	neutral	0,19	neutral	0,27	neutral	0,45	1	neutral	0,91	neutral	0,2	neutral	-3	deleterious	0,63	low_impact	-1,58	medium_impact	0,06	low_impact	-1	0,69	0,9	22,57	20,88	N	0,48	N	0,7	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9137	9137	T	G	MI.1300	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	611	204	I	S	aTc/aGc	-0,1	0	0	benign	0,16	neutral	0,46	neutral	4,15	neutral	-2,2	deleterious	-3,59	low_impact	1,62	neutral	0,81	neutral	0,5	deleterious	2,85	21,6	0,35	0,65	NA	NA	disease	0,61	disease	0,56	neutral	0,46	1	neutral	0,45	deleterious	0,65	neutral	-6	neutral	0,38	medium_impact	-0,07	medium_impact	0,25	medium_impact	0,29	0,37	0,9	27,88	21,96	N	0,27	N	0,46	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4587	4587	T	A	MI.13000	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	118	40	F	I	Ttt/Att	-10,56	0	0	benign	0,1	neutral	1	neutral	4,51	neutral	-1,07	neutral	1,91	neutral_impact	-0,86	neutral	0,87	neutral	0,92	neutral	1,51	13,36	0,14	0,4	neutral	0,19	neutral	0,22	neutral	0,14	neutral	0,36	3	neutral	0,1	deleterious	0,95	neutral	-6	neutral	0,21	medium_impact	0,08	high_impact	1,87	low_impact	-1,87	0,41	0,8	NA	NA	N	0,34	N	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4587	4587	T	G	MI.13001	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	118	40	F	V	Ttt/Gtt	-10,56	0	0	benign	0,43	neutral	0,24	neutral	4,5	neutral	-1,12	neutral	1,23	low_impact	1,15	neutral	0,9	neutral	0,94	deleterious	2,74	21	0,07	0,35	neutral	0,31	disease	0,73	neutral	0,28	neutral	0,21	6	neutral	0,72	neutral	0,41	neutral	-6	deleterious	0,58	medium_impact	-0,69	medium_impact	-0,07	medium_impact	-0,18	0,32	0,8	NA	NA	N	0,42	N	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4588	4588	T	G	MI.13002	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	119	40	F	C	tTt/tGt	4,63	1	0	probably_damaging	0,98	neutral	0,06	neutral	4,38	deleterious	-4,76	neutral	-1,84	medium_impact	2,71	neutral	0,79	damaging	0,22	deleterious	3,93	23,5	0,03	0,35	disease	0,68	disease	0,79	disease	0,55	disease	0,7	4	deleterious	0,99	neutral	0,04	deleterious	1	deleterious	0,79	low_impact	-2,34	medium_impact	-0,46	medium_impact	1,14	0,21	0,8	NA	NA	N	0,52	P	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4588	4588	T	A	MI.13003	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	119	40	F	Y	tTt/tAt	4,63	1	0	possibly_damaging	0,89	neutral	0,16	neutral	4,81	neutral	0,75	neutral	-1,15	medium_impact	2,16	neutral	0,89	damaging	0,26	deleterious	4,03	23,7	0,16	0,45	disease	0,55	disease	0,62	disease	0,51	neutral	0,49	0	neutral	0,94	neutral	0,14	NA	0	deleterious	0,75	low_impact	-1,63	medium_impact	-0,19	medium_impact	0,67	0,57	0,8	NA	NA	P	0,63	P	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4588	4588	T	C	MI.13004	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	119	40	F	S	tTt/tCt	4,63	1	0	probably_damaging	0,9	neutral	0,51	neutral	4,39	deleterious	-3,54	neutral	-2,49	medium_impact	2,71	neutral	0,76	damaging	0,21	deleterious	4,02	23,6	0,04	0,35	neutral	0,32	disease	0,74	disease	0,51	disease	0,54	1	neutral	0,89	neutral	0,31	deleterious	1	deleterious	0,74	low_impact	-1,67	medium_impact	0,22	medium_impact	1,14	0,29	0,8	NA	NA	N	0,51	P	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4589	4589	T	G	MI.13005	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	120	40	F	L	ttT/ttG	4,63	1	0	benign	0,43	neutral	0,4	neutral	4,68	neutral	0,17	neutral	0,75	low_impact	1,43	neutral	0,9	neutral	0,52	deleterious	4,1	23,7	0,19	0,45	neutral	0,28	disease	0,6	neutral	0,25	neutral	0,21	6	neutral	0,55	deleterious	0,49	neutral	-6	deleterious	0,51	medium_impact	-0,69	medium_impact	0,11	medium_impact	0,06	0,66	0,8	NA	NA	P	0,57	P	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4589	4589	T	A	MI.13006	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	120	40	F	L	ttT/ttA	4,63	1	0	benign	0,43	neutral	0,4	neutral	4,68	neutral	0,17	neutral	0,75	low_impact	1,43	neutral	0,9	neutral	0,52	deleterious	4,23	23,9	0,19	0,45	neutral	0,28	disease	0,6	neutral	0,25	neutral	0,21	6	neutral	0,55	deleterious	0,49	neutral	-6	deleterious	0,51	medium_impact	-0,69	medium_impact	0,11	medium_impact	0,06	0,66	0,8	NA	NA	P	0,57	P	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4590	4590	A	C	MI.13007	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	121	41	I	L	Att/Ctt	-8,49	0	0	benign	0,12	neutral	0,5	neutral	4,74	neutral	-0,38	neutral	-1,69	low_impact	1,2	neutral	0,85	neutral	0,54	deleterious	3,57	23,2	0,27	0,45	neutral	0,22	neutral	0,37	neutral	0,31	neutral	0,43	2	neutral	0,42	deleterious	0,69	neutral	-6	neutral	0,31	medium_impact	-0,01	medium_impact	0,21	medium_impact	-0,13	0,57	0,8	0,29	7,27	N	0,33	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4590	4590	A	G	MI.13008	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	121	41	I	V	Att/Gtt	-8,49	0	0	benign	0,02	neutral	0,28	neutral	4,51	neutral	-0,21	neutral	-0,64	low_impact	1,89	neutral	0,91	neutral	0,93	deleterious	1,81	15,07	0,38	0,5	neutral	0,4	neutral	0,45	neutral	0,41	neutral	0,41	2	neutral	0,71	deleterious	0,63	neutral	-6	neutral	0,19	medium_impact	0,75	medium_impact	-0,02	medium_impact	0,45	0,53	0,8	0,29	7,27	N	0,42	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4590	4590	A	T	MI.13009	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	121	41	I	F	Att/Ttt	-8,49	0	0	possibly_damaging	0,66	neutral	0,59	neutral	4,44	neutral	-0,96	deleterious	-3,47	medium_impact	3,43	neutral	0,86	neutral	0,41	deleterious	3,6	23,2	0,1	0,4	disease	0,62	disease	0,78	disease	0,67	disease	0,68	4	neutral	0,61	neutral	0,47	NA	0	deleterious	0,75	low_impact	-1,06	medium_impact	0,3	medium_impact	1,74	0,5	0,8	0,29	7,27	N	0,3	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9137	9137	T	A	MI.1301	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	611	204	I	N	aTc/aAc	-0,1	0	0	benign	0,32	deleterious	0,01	neutral	4,09	deleterious	-4,21	deleterious	-4,51	medium_impact	3,4	neutral	0,81	neutral	0,45	deleterious	4,51	24,3	0,31	0,65	NA	NA	disease	0,76	disease	0,57	disease	0,74	5	deleterious	0,99	neutral	0,35	deleterious	1	deleterious	0,6	medium_impact	-0,45	medium_impact	-0,84	medium_impact	1,82	0,35	0,9	27,88	21,96	N	0,36	N	0,63	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4591	4591	T	G	MI.13010	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	122	41	I	S	aTt/aGt	3,02	0,98	0	benign	0,37	neutral	0,29	neutral	4,38	neutral	-2,62	deleterious	-4,87	high_impact	3,78	neutral	0,86	neutral	0,44	deleterious	4,04	23,7	0,02	0,35	disease	0,55	disease	0,86	disease	0,68	disease	0,71	4	neutral	0,66	neutral	0,46	neutral	-2	deleterious	0,63	medium_impact	-0,59	medium_impact	-0,01	high_impact	2,04	0,25	0,8	0,29	7,27	P	0,59	P	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4591	4591	T	A	MI.13011	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	122	41	I	N	aTt/aAt	3,02	0,98	0	possibly_damaging	0,76	neutral	0,11	neutral	4,36	deleterious	-3,95	deleterious	-5,8	high_impact	3,78	neutral	0,88	neutral	0,41	deleterious	4,18	23,8	0,05	0,35	disease	0,61	disease	0,85	disease	0,7	disease	0,71	4	neutral	0,92	neutral	0,18	deleterious	1	deleterious	0,76	low_impact	-1,26	medium_impact	-0,3	high_impact	2,04	0,33	0,8	0,29	7,27	P	0,62	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4591	4591	T	C	MI.13012	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	122	41	I	T	aTt/aCt	3,02	0,98	0	benign	0,03	neutral	0,19	neutral	4,4	neutral	-2,16	deleterious	-3,63	medium_impact	2,34	neutral	0,98	neutral	0,69	deleterious	2,06	16,58	0,04	0,35	disease	0,53	disease	0,75	disease	0,59	neutral	0,46	1	neutral	0,8	deleterious	0,58	neutral	-3	neutral	0,29	medium_impact	0,59	medium_impact	-0,14	medium_impact	0,83	0,24	0,8	0,29	7,27	N	0,5	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4592	4592	T	A	MI.13013	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	123	41	I	M	atT/atA	5,55	0,99	0	benign	0,12	neutral	0,22	neutral	4,38	neutral	-2,37	neutral	-2,47	medium_impact	2,23	neutral	0,92	neutral	0,6	deleterious	3,61	23,2	0,14	0,4	disease	0,62	disease	0,68	disease	0,52	neutral	0,46	1	neutral	0,75	deleterious	0,55	neutral	-3	neutral	0,39	medium_impact	-0,01	medium_impact	-0,1	medium_impact	0,73	0,46	0,8	0,29	7,27	P	0,6	P	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4592	4592	T	G	MI.13014	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	123	41	I	M	atT/atG	5,55	0,99	0	benign	0,12	neutral	0,22	neutral	4,38	neutral	-2,37	neutral	-2,47	medium_impact	2,23	neutral	0,92	neutral	0,6	deleterious	3,29	22,8	0,14	0,4	disease	0,62	disease	0,68	disease	0,52	neutral	0,46	1	neutral	0,75	deleterious	0,55	neutral	-3	neutral	0,39	medium_impact	-0,01	medium_impact	-0,1	medium_impact	0,73	0,46	0,8	0,29	7,27	P	0,6	P	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4593	4593	C	T	MI.13015	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	124	42	P	S	Cca/Tca	-5,27	0	0	benign	0,14	neutral	0,52	neutral	4,64	neutral	-0,09	deleterious	-6,77	medium_impact	3,1	neutral	0,75	neutral	0,45	deleterious	3,72	23,3	0,1	0,4	disease	0,77	disease	0,83	disease	0,72	disease	0,62	2	neutral	0,39	deleterious	0,69	neutral	-3	deleterious	0,51	medium_impact	-0,08	medium_impact	0,23	medium_impact	1,47	0,13	0,8	NA	NA	N	0,28	N	0,72	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4593	4593	C	A	MI.13016	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	124	42	P	T	Cca/Aca	-5,27	0	0	possibly_damaging	0,76	neutral	0,4	neutral	4,62	neutral	-0,57	deleterious	-6,92	medium_impact	2,97	neutral	0,79	neutral	0,35	deleterious	3,53	23,1	0,07	0,35	disease	0,79	disease	0,85	disease	0,76	disease	0,72	4	neutral	0,77	neutral	0,32	NA	0	deleterious	0,81	low_impact	-1,26	medium_impact	0,11	medium_impact	1,36	0,43	0,8	NA	NA	N	0,3	N	0,88	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4593	4593	C	G	MI.13017	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	124	42	P	A	Cca/Gca	-5,27	0	0	possibly_damaging	0,66	neutral	0,53	neutral	4,63	neutral	-0,23	deleterious	-6,92	medium_impact	2,75	neutral	0,82	neutral	0,48	deleterious	2,95	22	0,08	0,35	disease	0,75	disease	0,71	disease	0,75	disease	0,72	4	neutral	0,62	neutral	0,44	NA	0	deleterious	0,74	low_impact	-1,06	medium_impact	0,24	medium_impact	1,17	0,52	0,8	NA	NA	N	0,26	N	0,72	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4594	4594	C	G	MI.13018	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	125	42	P	R	cCa/cGa	4,4	0,99	0	probably_damaging	0,93	neutral	0,34	neutral	4,59	neutral	-1,85	deleterious	-7,91	high_impact	4,07	neutral	0,83	neutral	0,36	deleterious	3,44	23	0,02	0,35	disease	0,82	disease	0,91	disease	0,84	disease	0,75	5	neutral	0,94	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-1,83	medium_impact	0,05	high_impact	2,28	0,31	0,8	NA	NA	P	0,67	P	0,56	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4594	4594	C	A	MI.13019	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	125	42	P	Q	cCa/cAa	4,4	0,99	0	probably_damaging	0,93	neutral	0,29	neutral	4,59	neutral	-1,97	deleterious	-6,98	high_impact	4,07	neutral	0,81	neutral	0,4	deleterious	3,87	23,5	0,06	0,35	disease	0,82	disease	0,89	disease	0,77	disease	0,72	4	neutral	0,94	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-1,83	medium_impact	-0,01	high_impact	2,28	0,29	0,8	NA	NA	P	0,64	P	0,83	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9137	9137	T	C	MI.1302	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	611	204	I	T	aTc/aCc	-0,1	0	0	benign	0,01	neutral	0,18	neutral	4,13	neutral	-2,57	deleterious	-2,72	low_impact	1,92	neutral	0,93	neutral	0,64	deleterious	0,69	8,73	0,58	0,7	NA	NA	neutral	0,41	neutral	0,36	neutral	0,16	7	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,16	medium_impact	1,14	medium_impact	-0,08	medium_impact	0,55	0,38	0,9	27,88	21,96	N	0,42	N	0,14	polymorphism	1	0,07	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	4594	4594	C	T	MI.13020	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	125	42	P	L	cCa/cTa	4,4	0,99	0	probably_damaging	0,91	neutral	0,76	neutral	5,34	neutral	3,74	deleterious	-8,83	medium_impact	3,27	neutral	0,94	neutral	0,41	deleterious	4,19	23,8	0,08	0,35	disease	0,64	disease	0,87	disease	0,71	disease	0,72	4	neutral	0,89	neutral	0,43	deleterious	1	deleterious	0,77	low_impact	-1,72	medium_impact	0,49	medium_impact	1,61	0,64	0,8	NA	NA	N	0,52	P	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4596	4596	G	T	MI.13021	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	127	43	V	F	Gtt/Ttt	-16,09	0	0	benign	0,22	neutral	0,4	neutral	4,47	neutral	-2,42	neutral	-2,34	neutral_impact	0,44	neutral	0,91	neutral	0,74	deleterious	3,51	23,1	0,04	0,35	neutral	0,35	disease	0,63	disease	0,66	neutral	0,5	0	neutral	0,52	deleterious	0,59	neutral	-6	deleterious	0,66	medium_impact	-0,29	medium_impact	0,11	medium_impact	-0,77	0,3	0,8	0,29	6,93	N	0,31	N	0,36	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4596	4596	G	C	MI.13022	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	127	43	V	L	Gtt/Ctt	-16,09	0	0	benign	0,01	neutral	1	neutral	4,59	neutral	-0,42	neutral	-0,05	neutral_impact	-1,57	neutral	0,89	neutral	0,95	neutral	-0,82	0,04	0,18	0,45	neutral	0,2	neutral	0,16	neutral	0,35	neutral	0,21	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,2	medium_impact	1,03	high_impact	1,87	low_impact	-2,47	0,38	0,8	0,29	6,93	N	0,36	N	0,18	polymorphism	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4596	4596	G	A	MI.13023	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	127	43	V	I	Gtt/Att	-16,09	0	0	benign	0	neutral	0,36	neutral	4,94	neutral	1,41	neutral	0,57	neutral_impact	-1,18	neutral	0,97	neutral	0,95	neutral	-1,17	0,01	0,54	0,6	neutral	0,29	neutral	0,15	neutral	0,37	neutral	0,26	5	neutral	0,64	deleterious	0,68	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,07	low_impact	-2,14	0,96	1	0,29	6,93	N	0,36	N	0,02	polymorphism	0,99	0,01	rs1117207	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4597	4597	T	A	MI.13024	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	128	43	V	D	gTt/gAt	-0,66	0	0	benign	0,36	neutral	0,06	neutral	4,44	deleterious	-4,28	deleterious	-5,18	low_impact	1,92	neutral	0,86	neutral	0,41	deleterious	4,43	24,2	0,01	0,35	disease	0,78	disease	0,76	disease	0,74	disease	0,72	4	neutral	0,93	neutral	0,35	neutral	-6	deleterious	0,78	medium_impact	-0,57	medium_impact	-0,46	medium_impact	0,47	0,1	0,8	0,29	6,93	N	0,34	N	0,66	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4597	4597	T	C	MI.13025	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	128	43	V	A	gTt/gCt	-0,66	0	0	benign	0,06	neutral	0,22	neutral	4,56	neutral	-0,77	deleterious	-3	low_impact	1,36	neutral	0,91	neutral	0,8	deleterious	1,82	15,13	0,06	0,35	neutral	0,2	neutral	0,35	disease	0,63	neutral	0,46	1	neutral	0,76	deleterious	0,58	neutral	-6	neutral	0,39	medium_impact	0,3	medium_impact	-0,1	medium_impact	0	0,23	0,8	0,29	6,93	N	0,47	N	0,26	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4597	4597	T	G	MI.13026	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	128	43	V	G	gTt/gGt	-0,66	0	0	benign	0,26	neutral	0,12	neutral	4,45	deleterious	-3,38	deleterious	-5,67	low_impact	1,92	neutral	0,9	neutral	0,47	deleterious	3,62	23,2	0,01	0,35	neutral	0,23	disease	0,57	disease	0,68	disease	0,71	4	neutral	0,86	neutral	0,43	neutral	-6	deleterious	0,66	medium_impact	-0,38	medium_impact	-0,27	medium_impact	0,47	0,15	0,8	0,29	6,93	N	0,43	N	0,57	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4599	4599	C	A	MI.13027	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	130	44	L	M	Cta/Ata	-9,18	0	0	probably_damaging	1	neutral	0,82	neutral	4,5	neutral	-1,6	neutral	-1,64	neutral_impact	-0,42	neutral	0,93	neutral	0,87	neutral	1,48	13,18	0,28	0,45	neutral	0,48	neutral	0,12	neutral	0,12	neutral	0,25	5	deleterious	1	neutral	0,41	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	0,57	low_impact	-1,5	0,54	0,8	1,15	7,68	N	0,34	N	0,13	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4599	4599	C	G	MI.13028	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	130	44	L	V	Cta/Gta	-9,18	0	0	probably_damaging	1	neutral	0,29	neutral	4,55	neutral	-0,02	neutral	-2,46	low_impact	1,74	neutral	0,87	damaging	0,17	deleterious	3,27	22,8	0,21	0,45	neutral	0,41	disease	0,6	disease	0,55	disease	0,66	3	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,75	low_impact	-3,54	medium_impact	-0,01	medium_impact	0,32	0,54	0,8	1,15	7,68	N	0,3	N	0,39	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4600	4600	T	A	MI.13029	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	131	44	L	Q	cTa/cAa	0,26	0,01	0	probably_damaging	1	neutral	0,14	neutral	4,48	deleterious	-3,59	deleterious	-5,39	medium_impact	2,89	neutral	0,85	damaging	0,13	deleterious	3,85	23,4	0,02	0,35	disease	0,52	disease	0,78	disease	0,56	disease	0,71	4	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,23	medium_impact	1,29	0,2	0,8	1,15	7,68	N	0,28	N	0,86	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9138	9138	C	G	MI.1303	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	612	204	I	M	atC/atG	4,76	0,73	0	possibly_damaging	0,59	neutral	0,29	neutral	4,12	neutral	-2,9	neutral	-1,16	low_impact	1,21	neutral	0,86	neutral	0,58	deleterious	2,03	16,39	0,5	0,65	NA	NA	neutral	0,39	neutral	0,26	neutral	0,18	6	neutral	0,72	neutral	0,35	neutral	-3	deleterious	0,58	medium_impact	-0,91	medium_impact	0,07	medium_impact	-0,06	0,56	0,9	27,88	21,96	N	0,42	N	0,64	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4600	4600	T	G	MI.13030	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	131	44	L	R	cTa/cGa	0,26	0,01	0	probably_damaging	1	neutral	0,23	neutral	4,48	deleterious	-3,24	deleterious	-5,42	medium_impact	2,89	neutral	0,77	damaging	0,1	deleterious	3,96	23,6	0,02	0,35	disease	0,72	disease	0,91	disease	0,69	disease	0,77	5	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,91	low_impact	-3,54	medium_impact	-0,08	medium_impact	1,29	0,13	0,8	1,15	7,68	N	0,25	N	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4600	4600	T	C	MI.13031	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	131	44	L	P	cTa/cCa	0,26	0,01	0	probably_damaging	1	neutral	0,25	neutral	4,46	deleterious	-3,97	deleterious	-6,29	medium_impact	2,54	neutral	0,69	damaging	0,09	deleterious	3,73	23,3	0,02	0,35	disease	0,81	disease	0,89	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,92	low_impact	-3,54	medium_impact	-0,06	medium_impact	0,99	0,19	0,8	1,15	7,68	N	0,24	N	0,97	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4602	4602	A	T	MI.13032	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	133	45	T	S	Acc/Tcc	-1,58	0	0	benign	0,19	neutral	0,53	neutral	4,65	neutral	0,17	neutral	-0,69	neutral_impact	0,24	neutral	0,77	neutral	0,72	deleterious	2,01	16,26	0,32	0,5	neutral	0,44	neutral	0,08	neutral	0,19	neutral	0,32	4	neutral	0,36	deleterious	0,67	neutral	-6	neutral	0,34	medium_impact	-0,22	medium_impact	0,24	medium_impact	-0,94	0,54	0,8	0,86	7,93	N	0,4	N	0,3	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4602	4602	A	G	MI.13033	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	133	45	T	A	Acc/Gcc	-1,58	0	0	benign	0,01	neutral	0,66	neutral	4,69	neutral	0,86	neutral	-0,52	neutral_impact	0,55	neutral	0,84	neutral	0,8	deleterious	1,88	15,49	0,27	0,45	neutral	0,41	neutral	0,13	neutral	0,18	neutral	0,27	5	neutral	0,32	deleterious	0,83	neutral	-6	neutral	0,16	medium_impact	1,03	medium_impact	0,37	medium_impact	-0,68	0,34	0,8	0,86	7,93	N	0,4	N	0,32	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4602	4602	A	C	MI.13034	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	133	45	T	P	Acc/Ccc	-1,58	0	0	possibly_damaging	0,64	neutral	0,25	neutral	4,6	neutral	-1,89	neutral	-1,79	medium_impact	2,13	neutral	0,81	neutral	0,49	deleterious	3,33	22,9	0,04	0,35	disease	0,79	disease	0,77	disease	0,68	disease	0,74	5	neutral	0,77	neutral	0,31	NA	0	deleterious	0,75	low_impact	-1,03	medium_impact	-0,06	medium_impact	0,65	0,31	0,8	0,86	7,93	N	0,28	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4603	4603	C	A	MI.13035	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	134	45	T	N	aCc/aAc	1,18	0	0	possibly_damaging	0,64	neutral	0,37	neutral	4,61	neutral	-1,5	neutral	-1,7	low_impact	1,1	neutral	0,89	neutral	0,73	deleterious	3,6	23,2	0,24	0,45	disease	0,73	disease	0,57	neutral	0,44	neutral	0,45	1	neutral	0,69	neutral	0,37	neutral	-3	deleterious	0,69	low_impact	-1,03	medium_impact	0,08	medium_impact	-0,22	0,54	0,8	0,86	7,93	N	0,39	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4603	4603	C	G	MI.13036	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	134	45	T	S	aCc/aGc	1,18	0	0	benign	0,19	neutral	0,53	neutral	4,65	neutral	0,17	neutral	-0,69	neutral_impact	0,24	neutral	0,77	neutral	0,72	deleterious	2,19	17,46	0,32	0,5	neutral	0,44	neutral	0,08	neutral	0,19	neutral	0,32	4	neutral	0,36	deleterious	0,67	neutral	-6	neutral	0,34	medium_impact	-0,22	medium_impact	0,24	medium_impact	-0,94	0,54	0,8	0,86	7,93	N	0,42	N	0,3	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4603	4603	C	T	MI.13037	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	134	45	T	I	aCc/aTc	1,18	0	0	benign	0,01	neutral	0,44	neutral	4,75	neutral	1,52	neutral	1,22	low_impact	0,84	neutral	0,96	neutral	0,97	deleterious	2,15	17,15	0,14	0,4	neutral	0,3	neutral	0,48	neutral	0,26	neutral	0,38	2	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,18	medium_impact	1,03	medium_impact	0,15	medium_impact	-0,44	0,59	0,8	0,86	7,93	N	0,38	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4605	4605	A	G	MI.13038	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	136	46	K	E	Aaa/Gaa	-5,27	0	0	probably_damaging	1	neutral	0,82	neutral	4,58	neutral	-1,41	deleterious	-2,79	medium_impact	1,98	neutral	0,92	damaging	0,24	deleterious	3,86	23,5	0,15	0,4	neutral	0,36	disease	0,84	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,41	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	0,57	medium_impact	0,52	0,44	0,8	8,93	9,1	N	0,27	N	0,65	polymorphism	1	0,05	.	.	.	.	.	head/neck tumor	.	.	.	.	.	.	.	.	.
chrM	4605	4605	A	C	MI.13039	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	136	46	K	Q	Aaa/Caa	-5,27	0	0	probably_damaging	1	neutral	0,72	neutral	4,58	neutral	-1,65	deleterious	-2,67	low_impact	1,38	neutral	0,9	damaging	0,28	deleterious	2,11	16,92	0,3	0,45	neutral	0,22	disease	0,59	neutral	0,3	neutral	0,21	6	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	0,44	medium_impact	0,02	0,29	0,8	8,93	9,1	N	0,23	N	0,64	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9138	9138	C	A	MI.1304	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	612	204	I	M	atC/atA	4,76	0,73	0	possibly_damaging	0,59	neutral	0,29	neutral	4,12	neutral	-2,9	neutral	-1,16	low_impact	1,21	neutral	0,86	neutral	0,58	deleterious	2,51	19,51	0,5	0,65	NA	NA	neutral	0,39	neutral	0,26	neutral	0,18	6	neutral	0,72	neutral	0,35	neutral	-3	deleterious	0,58	medium_impact	-0,91	medium_impact	0,07	medium_impact	-0,06	0,56	0,9	27,88	21,96	N	0,42	N	0,64	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4606	4606	A	C	MI.13040	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	137	46	K	T	aAa/aCa	0,72	0	0	probably_damaging	1	neutral	0,7	neutral	4,62	neutral	-0,34	deleterious	-4,1	medium_impact	2,18	neutral	0,92	neutral	0,29	deleterious	3,37	22,9	0,11	0,4	neutral	0,48	disease	0,76	neutral	0,39	neutral	0,22	6	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,41	medium_impact	0,69	0,25	0,8	8,93	9,1	N	0,26	N	0,61	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4606	4606	A	T	MI.13041	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	137	46	K	M	aAa/aTa	0,72	0	0	probably_damaging	1	neutral	0,26	neutral	4,58	neutral	-1,37	deleterious	-4,01	medium_impact	2,08	neutral	0,94	damaging	0,24	deleterious	3,8	23,4	0,11	0,4	disease	0,74	disease	0,77	neutral	0,49	neutral	0,42	2	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,04	medium_impact	0,61	0,17	0,8	8,93	9,1	N	0,4	N	0,7	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4607	4607	A	C	MI.13042	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	138	46	K	N	aaA/aaC	1,87	0	0	probably_damaging	1	neutral	0,61	neutral	4,59	neutral	-1,02	deleterious	-2,94	low_impact	1,47	neutral	0,91	neutral	0,75	deleterious	2,24	17,8	0,39	0,5	neutral	0,24	disease	0,75	neutral	0,36	neutral	0,22	6	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,77	low_impact	-3,54	medium_impact	0,32	medium_impact	0,09	0,35	0,8	8,93	9,1	N	0,27	N	0,34	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4607	4607	A	T	MI.13043	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	138	46	K	N	aaA/aaT	1,87	0	0	probably_damaging	1	neutral	0,61	neutral	4,59	neutral	-1,02	deleterious	-2,94	low_impact	1,47	neutral	0,91	neutral	0,75	deleterious	2,32	18,3	0,39	0,5	neutral	0,24	disease	0,75	neutral	0,36	neutral	0,22	6	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,77	low_impact	-3,54	medium_impact	0,32	medium_impact	0,09	0,35	0,8	8,93	9,1	N	0,27	N	0,34	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4608	4608	A	C	MI.13044	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	139	47	K	Q	Aaa/Caa	0,03	0	0	probably_damaging	0,9	neutral	0,35	neutral	4,63	neutral	-1,44	neutral	-1,83	low_impact	0,89	neutral	0,87	neutral	0,79	neutral	1,59	13,8	0,37	0,5	disease	0,58	neutral	0,25	neutral	0,22	disease	0,55	1	neutral	0,91	neutral	0,23	neutral	-2	deleterious	0,69	low_impact	-1,67	medium_impact	0,06	medium_impact	-0,4	0,23	0,8	0,86	8,89	N	0,43	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4608	4608	A	G	MI.13045	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	139	47	K	E	Aaa/Gaa	0,03	0	0	possibly_damaging	0,64	neutral	0,34	neutral	4,61	neutral	-1,1	neutral	-2,04	low_impact	1,59	neutral	0,9	neutral	0,5	deleterious	2,35	18,47	0,2	0,45	disease	0,55	disease	0,63	neutral	0,45	neutral	0,46	1	neutral	0,71	neutral	0,35	neutral	-3	deleterious	0,68	low_impact	-1,03	medium_impact	0,05	medium_impact	0,19	0,4	0,8	0,86	8,89	N	0,43	N	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4609	4609	A	T	MI.13046	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	140	47	K	M	aAa/aTa	0,26	0	0	probably_damaging	0,98	neutral	0,25	neutral	4,55	deleterious	-3,96	deleterious	-3,82	low_impact	1,7	neutral	0,86	neutral	0,29	deleterious	3,46	23	0,17	0,45	disease	0,87	neutral	0,32	neutral	0,28	disease	0,65	3	deleterious	0,98	neutral	0,14	neutral	-2	deleterious	0,76	low_impact	-2,34	medium_impact	-0,06	medium_impact	0,29	0,17	0,8	0,86	8,89	N	0,37	N	0,81	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4609	4609	A	C	MI.13047	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	140	47	K	T	aAa/aCa	0,26	0	0	possibly_damaging	0,67	neutral	0,44	neutral	4,57	neutral	-1,91	deleterious	-3,24	low_impact	0,88	neutral	0,87	neutral	0,9	deleterious	2	16,21	0,2	0,45	disease	0,69	neutral	0,33	neutral	0,29	disease	0,62	2	neutral	0,67	neutral	0,39	neutral	-3	deleterious	0,66	low_impact	-1,08	medium_impact	0,15	medium_impact	-0,4	0,15	0,8	0,86	8,89	N	0,37	N	0,72	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4610	4610	A	T	MI.13048	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	141	47	K	N	aaA/aaT	0,95	0	0	benign	0,06	neutral	0,39	neutral	4,62	neutral	-1,32	neutral	-1,5	neutral_impact	0,64	neutral	0,88	neutral	0,88	deleterious	2,01	16,25	0,58	0,65	neutral	0,43	neutral	0,39	neutral	0,26	neutral	0,46	1	neutral	0,57	deleterious	0,67	neutral	-6	neutral	0,21	medium_impact	0,3	medium_impact	0,1	medium_impact	-0,61	0,28	0,8	0,86	8,89	N	0,42	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4610	4610	A	C	MI.13049	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	141	47	K	N	aaA/aaC	0,95	0	0	benign	0,06	neutral	0,39	neutral	4,62	neutral	-1,32	neutral	-1,5	neutral_impact	0,64	neutral	0,88	neutral	0,88	deleterious	1,95	15,88	0,58	0,65	neutral	0,43	neutral	0,39	neutral	0,26	neutral	0,46	1	neutral	0,57	deleterious	0,67	neutral	-6	neutral	0,21	medium_impact	0,3	medium_impact	0,1	medium_impact	-0,61	0,28	0,8	0,86	8,89	N	0,41	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9139	9139	G	C	MI.1305	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	613	205	A	P	Gct/Cct	-7,28	0	0	probably_damaging	1	neutral	0,05	neutral	4,22	deleterious	-3,67	deleterious	-4,16	high_impact	4,25	damaging	0,46	neutral	0,44	deleterious	3,89	23,5	0,14	0,65	NA	NA	disease	0,94	disease	0,72	disease	0,86	7	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,94	low_impact	-3,6	medium_impact	-0,43	high_impact	2,54	0,77	0,9	15,93	18,3	N	0,49	N	0,97	disease_causing	0,93	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4611	4611	A	T	MI.13050	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	142	48	M	L	Ata/Tta	-7,8	0	0	benign	0,02	neutral	0,65	neutral	4,66	neutral	1,32	neutral	-0,54	neutral_impact	0,2	neutral	0,91	neutral	0,6	neutral	-0,08	1,87	0,39	0,5	neutral	0,31	neutral	0,48	neutral	0,45	neutral	0,44	1	neutral	0,31	deleterious	0,82	neutral	-6	neutral	0,2	medium_impact	0,75	medium_impact	0,36	medium_impact	-0,98	0,25	0,8	18,44	10,65	N	0,33	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4611	4611	A	G	MI.13051	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	142	48	M	V	Ata/Gta	-7,8	0	0	benign	0,04	neutral	0,49	neutral	4,69	neutral	1	neutral	-0,44	neutral_impact	0,3	neutral	0,85	neutral	0,67	neutral	-0,58	0,14	0,38	0,5	neutral	0,32	disease	0,57	neutral	0,47	neutral	0,47	1	neutral	0,47	deleterious	0,73	neutral	-6	neutral	0,22	medium_impact	0,47	medium_impact	0,2	medium_impact	-0,89	0,3	0,8	18,44	10,65	N	0,25	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4611	4611	A	C	MI.13052	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	142	48	M	L	Ata/Cta	-7,8	0	0	benign	0,02	neutral	0,65	neutral	4,66	neutral	1,32	neutral	-0,54	neutral_impact	0,2	neutral	0,91	neutral	0,6	neutral	-0,16	1,34	0,39	0,5	neutral	0,31	neutral	0,48	neutral	0,45	neutral	0,44	1	neutral	0,31	deleterious	0,82	neutral	-6	neutral	0,2	medium_impact	0,75	medium_impact	0,36	medium_impact	-0,98	0,25	0,8	18,44	10,65	N	0,33	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4612	4612	T	A	MI.13053	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	143	48	M	K	aTa/aAa	-1,12	0	0,01	benign	0,12	neutral	0,55	neutral	4,84	neutral	3,11	neutral	-0,41	neutral_impact	-1,63	neutral	0,91	neutral	0,87	deleterious	0,66	8,59	0,16	0,45	neutral	0,37	disease	0,75	disease	0,51	neutral	0,43	1	neutral	0,36	deleterious	0,72	neutral	-6	neutral	0,33	medium_impact	-0,01	medium_impact	0,26	low_impact	-2,52	0,17	0,8	18,44	10,65	N	0,28	N	0,33	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4612	4612	T	C	MI.13054	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	143	48	M	T	aTa/aCa	-1,12	0	0,01	benign	0	neutral	0,45	neutral	4,75	neutral	2,2	neutral	-0,01	neutral_impact	-0,22	neutral	0,97	neutral	0,92	neutral	-0,49	0,23	0,22	0,45	neutral	0,38	neutral	0,49	neutral	0,39	neutral	0,24	5	neutral	0,55	deleterious	0,73	neutral	-6	neutral	0,21	medium_impact	1,95	medium_impact	0,16	low_impact	-1,33	0,11	0,8	18,44	10,65	N	0,33	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4613	4613	A	T	MI.13055	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	144	48	M	I	atA/atT	0,03	0	0	benign	0,08	neutral	0,51	neutral	4,67	neutral	0,63	neutral	-0,59	neutral_impact	0,12	neutral	0,89	neutral	0,63	deleterious	0,16	4,27	0,32	0,5	neutral	0,32	disease	0,54	neutral	0,46	neutral	0,47	1	neutral	0,42	deleterious	0,72	neutral	-6	neutral	0,34	medium_impact	0,17	medium_impact	0,22	low_impact	-1,04	0,36	0,8	18,44	10,65	N	0,32	N	0,23	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4613	4613	A	C	MI.13056	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	144	48	M	I	atA/atC	0,03	0	0	benign	0,08	neutral	0,51	neutral	4,67	neutral	0,63	neutral	-0,59	neutral_impact	0,12	neutral	0,89	neutral	0,63	deleterious	0,08	3,43	0,32	0,5	neutral	0,32	disease	0,54	neutral	0,46	neutral	0,47	1	neutral	0,42	deleterious	0,72	neutral	-6	neutral	0,34	medium_impact	0,17	medium_impact	0,22	low_impact	-1,04	0,36	0,8	18,44	10,65	N	0,32	N	0,23	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4614	4614	A	C	MI.13057	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	145	49	N	H	Aac/Cac	-3,19	0	0	possibly_damaging	0,69	neutral	0,93	neutral	4,59	neutral	-1,46	deleterious	-3,69	neutral_impact	-0,11	neutral	0,86	neutral	0,94	neutral	1,03	10,83	0,76	0,8	neutral	0,48	neutral	0,06	neutral	0,33	neutral	0,2	6	neutral	0,66	deleterious	0,62	neutral	-3	deleterious	0,67	low_impact	-1,12	medium_impact	0,83	low_impact	-1,24	0,19	0,8	NA	NA	N	0,3	N	0,06	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4614	4614	A	T	MI.13058	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	145	49	N	Y	Aac/Tac	-3,19	0	0	possibly_damaging	0,6	neutral	1	neutral	4,6	neutral	-1,4	deleterious	-5,88	medium_impact	1,98	neutral	0,86	neutral	0,49	deleterious	3,49	23,1	0,23	0,45	disease	0,87	disease	0,71	disease	0,7	disease	0,7	4	neutral	0,6	deleterious	0,7	NA	0	deleterious	0,84	medium_impact	-0,96	high_impact	1,87	medium_impact	0,52	0,21	0,8	NA	NA	N	0,18	N	0,6	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4614	4614	A	G	MI.13059	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	145	49	N	D	Aac/Gac	-3,19	0	0	benign	0,13	neutral	0,33	neutral	4,65	neutral	0,18	deleterious	-3,5	medium_impact	2,27	neutral	0,85	neutral	0,4	deleterious	1,99	16,13	0,77	0,8	neutral	0,23	disease	0,65	disease	0,69	disease	0,7	4	neutral	0,62	deleterious	0,6	neutral	-3	deleterious	0,58	medium_impact	-0,04	medium_impact	0,04	medium_impact	0,77	0,33	0,8	NA	NA	N	0,34	N	0,42	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9139	9139	G	A	MI.1306	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	613	205	A	T	Gct/Act	-7,28	0	0	probably_damaging	1	neutral	0,06	neutral	4,26	neutral	-1,76	deleterious	-2,95	high_impact	3,7	neutral	0,74	neutral	0,55	deleterious	4,25	23,9	0,37	0,65	NA	NA	disease	0,87	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,38	high_impact	2,07	0,66	0,9	15,93	18,3	N	0,43	N	0,8	disease_causing	0,79	0,22	rs879243938	.	.	.	.	.	.	CPD	0,15	G9139A	LHON	+	-	Reported-possibly synergistic	1
chrM	4615	4615	A	T	MI.13060	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	146	49	N	I	aAc/aTc	0,95	0	0	possibly_damaging	0,52	neutral	0,54	neutral	4,59	neutral	-1,96	deleterious	-6,5	medium_impact	2,38	neutral	0,87	neutral	0,48	deleterious	3,48	23,1	0,21	0,45	disease	0,85	disease	0,73	disease	0,65	disease	0,7	4	neutral	0,49	deleterious	0,51	NA	0	deleterious	0,82	medium_impact	-0,83	medium_impact	0,25	medium_impact	0,86	0,13	0,8	NA	NA	N	0,28	N	0,67	polymorphism	1	0,08	rs386828946	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4615	4615	A	G	MI.13061	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	146	49	N	S	aAc/aGc	0,95	0	0	benign	0	neutral	0,76	neutral	4,83	neutral	1,87	deleterious	-2,55	neutral_impact	0,58	neutral	0,95	neutral	0,99	neutral	-0,52	0,19	0,7	0,75	neutral	0,47	neutral	0,5	neutral	0,45	neutral	0,24	5	neutral	0,23	deleterious	0,88	neutral	-6	neutral	0,24	medium_impact	1,95	medium_impact	0,49	medium_impact	-0,66	0,38	0,8	NA	NA	N	0,33	N	0	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4615	4615	A	C	MI.13062	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	146	49	N	T	aAc/aCc	0,95	0	0	benign	0,13	neutral	0,52	neutral	4,64	neutral	-0,02	deleterious	-3,52	low_impact	1,06	neutral	0,89	neutral	0,76	deleterious	0,34	6,11	0,56	0,6	disease	0,67	disease	0,51	neutral	0,43	neutral	0,3	4	neutral	0,39	deleterious	0,7	neutral	-6	deleterious	0,62	medium_impact	-0,04	medium_impact	0,23	medium_impact	-0,25	0,34	0,8	NA	NA	N	0,36	N	0,04	polymorphism	1	0,06	rs386828946	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4616	4616	C	A	MI.13063	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	147	49	N	K	aaC/aaA	0,72	0	0	benign	0,01	neutral	0,62	neutral	4,79	neutral	1,58	deleterious	-4,11	low_impact	1,66	neutral	0,86	neutral	0,58	deleterious	2,59	20,1	0,64	0,7	disease	0,57	disease	0,71	disease	0,7	disease	0,72	4	neutral	0,36	deleterious	0,81	neutral	-6	neutral	0,34	medium_impact	1,03	medium_impact	0,33	medium_impact	0,25	0,46	0,8	NA	NA	N	0,27	N	0,4	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4616	4616	C	G	MI.13064	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	147	49	N	K	aaC/aaG	0,72	0	0	benign	0,01	neutral	0,62	neutral	4,79	neutral	1,58	deleterious	-4,11	low_impact	1,66	neutral	0,86	neutral	0,58	deleterious	2,15	17,2	0,64	0,7	disease	0,57	disease	0,71	disease	0,7	disease	0,72	4	neutral	0,36	deleterious	0,81	neutral	-6	neutral	0,34	medium_impact	1,03	medium_impact	0,33	medium_impact	0,25	0,46	0,8	NA	NA	N	0,27	N	0,4	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4617	4617	C	A	MI.13065	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	148	50	P	T	Cct/Act	-0,2	0	0	benign	0,05	neutral	0,57	neutral	4,56	neutral	-1,23	deleterious	-7,28	medium_impact	2,27	neutral	0,79	neutral	0,54	deleterious	3,71	23,3	0,36	0,5	neutral	0,43	disease	0,84	disease	0,6	disease	0,69	4	neutral	0,38	deleterious	0,76	neutral	-3	neutral	0,31	medium_impact	0,37	medium_impact	0,28	medium_impact	0,77	0,41	0,8	NA	NA	N	0,24	N	0,4	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4617	4617	C	T	MI.13066	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	148	50	P	S	Cct/Tct	-0,2	0	0	benign	0,03	neutral	0,89	neutral	4,62	neutral	-0,79	deleterious	-7,26	medium_impact	2	neutral	0,86	neutral	0,66	deleterious	3,65	23,2	0,4	0,5	neutral	0,4	disease	0,85	disease	0,59	disease	0,57	1	neutral	0,05	deleterious	0,93	neutral	-3	neutral	0,31	medium_impact	0,59	medium_impact	0,71	medium_impact	0,54	0,28	0,8	NA	NA	N	0,25	N	0,68	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4617	4617	C	G	MI.13067	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	148	50	P	A	Cct/Gct	-0,2	0	0	benign	0,02	neutral	0,76	neutral	4,59	neutral	-0,13	deleterious	-7,28	medium_impact	3,04	neutral	0,82	neutral	0,65	deleterious	2,93	22	0,43	0,55	neutral	0,38	disease	0,67	disease	0,67	disease	0,66	3	neutral	0,2	deleterious	0,87	neutral	-3	neutral	0,24	medium_impact	0,75	medium_impact	0,49	medium_impact	1,42	0,59	0,8	NA	NA	N	0,27	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4618	4618	C	A	MI.13068	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	149	50	P	H	cCt/cAt	3,48	0,99	0	probably_damaging	0,93	neutral	0,43	neutral	4,51	neutral	-2,35	deleterious	-8,23	medium_impact	3,15	neutral	0,81	neutral	0,35	deleterious	3,78	23,4	0,18	0,45	disease	0,66	disease	0,84	disease	0,72	disease	0,72	4	neutral	0,93	neutral	0,25	deleterious	1	deleterious	0,82	low_impact	-1,83	medium_impact	0,14	medium_impact	1,51	0,21	0,8	NA	NA	N	0,48	N	0,91	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4618	4618	C	T	MI.13069	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	149	50	P	L	cCt/cTt	3,48	0,99	0	benign	0,03	neutral	0,78	neutral	4,6	neutral	-1,03	deleterious	-9,12	medium_impact	2,02	neutral	0,79	neutral	0,43	deleterious	4,17	23,8	0,25	0,45	neutral	0,3	disease	0,86	disease	0,65	disease	0,71	4	neutral	0,16	deleterious	0,88	neutral	-3	neutral	0,26	medium_impact	0,59	medium_impact	0,51	medium_impact	0,56	0,65	0,8	NA	NA	N	0,42	N	0,5	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9139	9139	G	T	MI.1307	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	613	205	A	S	Gct/Tct	-7,28	0	0	probably_damaging	0,99	neutral	0,13	neutral	4,26	neutral	-2,07	neutral	-2,32	medium_impact	2,75	damaging	0,59	neutral	0,58	deleterious	3,79	23,4	0,32	0,65	NA	NA	disease	0,89	disease	0,59	disease	0,67	3	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,91	low_impact	-2,65	medium_impact	-0,18	medium_impact	1,26	0,62	0,9	15,93	18,3	N	0,33	N	0,95	disease_causing	0,63	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4618	4618	C	G	MI.13070	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	149	50	P	R	cCt/cGt	3,48	0,99	0	possibly_damaging	0,76	neutral	0,5	neutral	4,54	neutral	-0,49	deleterious	-8,23	medium_impact	2,81	neutral	0,83	neutral	0,37	deleterious	3,47	23	0,12	0,4	disease	0,53	disease	0,89	disease	0,73	disease	0,73	5	neutral	0,74	neutral	0,37	NA	0	deleterious	0,78	low_impact	-1,26	medium_impact	0,21	medium_impact	1,22	0,27	0,8	NA	NA	N	0,48	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4620	4620	C	T	MI.13071	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	151	51	R	C	Cgt/Tgt	-8,95	0	0	probably_damaging	1	neutral	0,16	neutral	4,46	deleterious	-5,77	deleterious	-7,46	high_impact	3,86	neutral	0,75	damaging	0,05	deleterious	4,92	25	0,08	0,35	disease	0,74	disease	0,88	disease	0,76	disease	0,72	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	-0,19	high_impact	2,11	0,82	0,85	NA	NA	N	0,33	N	1	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4620	4620	C	A	MI.13072	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	151	51	R	S	Cgt/Agt	-8,95	0	0	probably_damaging	1	neutral	0,7	neutral	4,58	neutral	-1,56	deleterious	-5,6	medium_impact	2,12	neutral	0,88	damaging	0,1	deleterious	4,52	24,3	0,1	0,4	neutral	0,48	disease	0,89	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0,41	medium_impact	0,64	0,26	0,8	NA	NA	N	0,23	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4620	4620	C	G	MI.13073	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	151	51	R	G	Cgt/Ggt	-8,95	0	0	probably_damaging	1	neutral	0,35	neutral	4,49	neutral	-2,22	deleterious	-6,53	medium_impact	2,82	neutral	0,76	damaging	0,09	deleterious	4,12	23,8	0,09	0,35	disease	0,64	disease	0,84	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	0,06	medium_impact	1,23	0,16	0,8	NA	NA	N	0,24	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4621	4621	G	A	MI.13074	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	152	51	R	H	cGt/cAt	2,79	0,98	0	probably_damaging	1	neutral	0,52	neutral	4,49	deleterious	-3,19	deleterious	-4,66	medium_impact	3,31	neutral	0,74	damaging	0,05	deleterious	4,26	23,9	0,26	0,45	disease	0,69	disease	0,83	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	0,23	medium_impact	1,64	0,91	0,95	NA	NA	N	0,48	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4621	4621	G	C	MI.13075	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	152	51	R	P	cGt/cCt	2,79	0,98	0	probably_damaging	1	neutral	0,26	neutral	4,48	deleterious	-3,41	deleterious	-6,53	medium_impact	2,96	neutral	0,76	damaging	0,06	deleterious	4,07	23,7	0,04	0,35	disease	0,71	disease	0,9	disease	0,81	disease	0,74	5	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,88	low_impact	-3,54	medium_impact	-0,04	medium_impact	1,35	0,11	0,8	NA	NA	N	0,49	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4621	4621	G	T	MI.13076	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	152	51	R	L	cGt/cTt	2,79	0,98	0	probably_damaging	1	neutral	0,73	neutral	4,51	neutral	-1,86	deleterious	-6,53	low_impact	1,93	neutral	0,7	damaging	0,06	deleterious	4,19	23,8	0,1	0,4	neutral	0,37	disease	0,92	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,37	neutral	-2	deleterious	0,83	low_impact	-3,54	medium_impact	0,45	medium_impact	0,48	0,05	0,8	NA	NA	N	0,4	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4623	4623	T	G	MI.13077	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	154	52	S	A	Tcc/Gcc	-0,43	0,01	0	probably_damaging	1	neutral	0,94	neutral	4,59	neutral	-1,14	neutral	-1,5	neutral_impact	-0,38	neutral	0,9	neutral	0,97	neutral	1,54	13,5	0,35	0,5	neutral	0,41	neutral	0,07	neutral	0,21	neutral	0,34	3	deleterious	0,99	deleterious	0,47	neutral	-2	deleterious	0,7	low_impact	-3,54	medium_impact	0,87	low_impact	-1,46	0,39	0,8	0,86	6,84	N	0,35	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4623	4623	T	C	MI.13078	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	154	52	S	P	Tcc/Ccc	-0,43	0,01	0	probably_damaging	1	neutral	0,22	neutral	4,37	deleterious	-4,41	deleterious	-3,97	medium_impact	2,18	neutral	0,76	damaging	0,18	deleterious	3,81	23,4	0,06	0,35	disease	0,87	disease	0,92	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,93	low_impact	-3,54	medium_impact	-0,1	medium_impact	0,69	0,15	0,8	0,86	6,84	N	0,28	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4623	4623	T	A	MI.13079	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	154	52	S	T	Tcc/Acc	-0,43	0,01	0	probably_damaging	1	neutral	0,38	neutral	4,42	neutral	-2,76	neutral	-2,21	low_impact	1,27	neutral	0,91	neutral	0,8	deleterious	2,54	19,71	0,32	0,5	disease	0,7	disease	0,56	neutral	0,48	neutral	0,34	3	deleterious	1	neutral	0,19	neutral	-2	deleterious	0,82	low_impact	-3,54	medium_impact	0,09	medium_impact	-0,08	0,5	0,8	0,86	6,84	N	0,39	N	0,47	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9140	9140	C	T	MI.1308	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	614	205	A	V	gCt/gTt	6,14	1	0	probably_damaging	1	neutral	0,09	neutral	4,3	neutral	-0,55	deleterious	-3,3	medium_impact	3,28	damaging	0,47	neutral	0,44	deleterious	4,53	24,3	0,35	0,65	NA	NA	disease	0,92	disease	0,58	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,92	low_impact	-3,6	medium_impact	-0,28	medium_impact	1,71	0,64	0,9	15,93	18,3	P	0,66	P	0,75	disease_causing	1	0,09	rs878972895	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4624	4624	C	A	MI.13080	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	155	52	S	Y	tCc/tAc	0,49	0,11	0	probably_damaging	1	neutral	1	neutral	4,36	deleterious	-4,8	deleterious	-4,9	medium_impact	2,35	neutral	0,86	damaging	0,13	deleterious	3,88	23,5	0,07	0,35	disease	0,93	disease	0,84	disease	0,65	disease	0,72	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,91	low_impact	-3,54	high_impact	1,87	medium_impact	0,83	0,13	0,8	0,86	6,84	N	0,21	N	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4624	4624	C	G	MI.13081	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	155	52	S	C	tCc/tGc	0,49	0,11	0	probably_damaging	1	neutral	0,17	neutral	4,35	deleterious	-6,34	deleterious	-3,76	medium_impact	2,6	neutral	0,77	damaging	0,12	deleterious	3,44	23	0,08	0,35	disease	0,92	disease	0,8	disease	0,6	disease	0,7	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,88	low_impact	-3,54	medium_impact	-0,17	medium_impact	1,04	0,24	0,8	0,86	6,84	N	0,3	N	0,57	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4624	4624	C	T	MI.13082	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	155	52	S	F	tCc/tTc	0,49	0,11	0	probably_damaging	1	neutral	0,66	neutral	4,36	deleterious	-5,52	deleterious	-4,9	medium_impact	2,35	neutral	0,79	damaging	0,11	deleterious	4,12	23,8	0,08	0,35	disease	0,93	disease	0,86	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,91	low_impact	-3,54	medium_impact	0,37	medium_impact	0,83	0,03	0,8	0,86	6,84	N	0,22	N	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4626	4626	A	T	MI.13083	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	157	53	T	S	Aca/Tca	-5,27	0	0	possibly_damaging	0,79	neutral	0,91	neutral	4,63	neutral	-0,18	neutral	-2,32	low_impact	1	neutral	0,88	neutral	0,56	deleterious	3,24	22,8	0,34	0,5	disease	0,51	disease	0,6	disease	0,51	disease	0,5	0	neutral	0,77	deleterious	0,56	neutral	-3	deleterious	0,72	low_impact	-1,32	medium_impact	0,77	medium_impact	-0,3	0,43	0,8	NA	NA	N	0,28	N	0,71	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4626	4626	A	C	MI.13084	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	157	53	T	P	Aca/Cca	-5,27	0	0	probably_damaging	0,98	neutral	0,24	neutral	4,54	neutral	-2,9	deleterious	-3,8	medium_impact	2,29	neutral	0,78	neutral	0,32	deleterious	3,35	22,9	0,03	0,35	disease	0,79	disease	0,86	disease	0,66	disease	0,73	5	deleterious	0,98	neutral	0,13	deleterious	1	deleterious	0,87	low_impact	-2,34	medium_impact	-0,07	medium_impact	0,78	0,17	0,8	NA	NA	N	0,26	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4626	4626	A	G	MI.13085	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	157	53	T	A	Aca/Gca	-5,27	0	0	benign	0,16	neutral	0,68	neutral	4,65	neutral	0,13	deleterious	-2,73	low_impact	1,59	neutral	0,92	neutral	0,81	deleterious	3,3	22,9	0,24	0,45	neutral	0,47	neutral	0,43	disease	0,52	neutral	0,47	1	neutral	0,2	deleterious	0,76	neutral	-6	neutral	0,29	medium_impact	-0,14	medium_impact	0,39	medium_impact	0,19	0,31	0,8	NA	NA	N	0,27	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4627	4627	C	A	MI.13086	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	158	53	T	K	aCa/aAa	1,41	0	0	probably_damaging	0,94	neutral	0,57	neutral	4,58	neutral	-1,06	deleterious	-3,54	medium_impact	2,04	neutral	0,85	neutral	0,39	deleterious	4,33	24	0,06	0,35	disease	0,71	disease	0,82	disease	0,66	disease	0,72	4	neutral	0,93	neutral	0,32	deleterious	1	deleterious	0,83	low_impact	-1,89	medium_impact	0,28	medium_impact	0,57	0,26	0,8	NA	NA	N	0,21	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4627	4627	C	T	MI.13087	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	158	53	T	M	aCa/aTa	1,41	0	0	probably_damaging	0,99	neutral	0,37	neutral	4,6	neutral	-0,68	neutral	-1,51	low_impact	1,76	neutral	0,91	neutral	0,95	deleterious	2,45	19,15	0,1	0,4	neutral	0,19	disease	0,51	neutral	0,28	neutral	0,23	5	deleterious	0,99	neutral	0,19	neutral	-2	deleterious	0,68	low_impact	-2,62	medium_impact	0,08	medium_impact	0,34	0,52	0,8	NA	NA	N	0,39	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4629	4629	G	C	MI.13088	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	160	54	E	Q	Gaa/Caa	-1,81	0	0	probably_damaging	1	neutral	0,31	neutral	4,46	deleterious	-3,38	deleterious	-2,8	medium_impact	3,04	neutral	0,86	damaging	0,13	deleterious	3,2	22,7	0,13	0,4	disease	0,71	disease	0,85	disease	0,56	disease	0,67	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	0,02	medium_impact	1,42	0,57	0,8	NA	NA	N	0,3	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4629	4629	G	A	MI.13089	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	160	54	E	K	Gaa/Aaa	-1,81	0	0	probably_damaging	1	neutral	0,44	neutral	4,53	neutral	-2,49	deleterious	-3,73	medium_impact	3,11	neutral	0,87	damaging	0,11	deleterious	4,31	24	0,05	0,35	disease	0,65	disease	0,91	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,89	low_impact	-3,54	medium_impact	0,15	medium_impact	1,47	0,8	0,85	NA	NA	N	0,36	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9140	9140	C	A	MI.1309	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	614	205	A	D	gCt/gAt	6,14	1	0	probably_damaging	1	deleterious	0,03	neutral	4,22	deleterious	-4,22	deleterious	-4,89	high_impact	4,25	neutral	0,63	neutral	0,45	deleterious	4,58	24,4	0,15	0,65	NA	NA	disease	0,96	disease	0,72	disease	0,86	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,94	low_impact	-3,6	medium_impact	-0,56	high_impact	2,54	0,55	0,9	15,93	18,3	P	0,51	P	0,99	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4630	4630	A	T	MI.13090	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	161	54	E	V	gAa/gTa	5,09	1	0	probably_damaging	1	neutral	0,52	neutral	4,38	deleterious	-4,37	deleterious	-6,53	high_impact	3,54	neutral	0,77	damaging	0,12	deleterious	3,93	23,5	0,02	0,35	disease	0,53	disease	0,9	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	0,23	medium_impact	1,84	0,22	0,8	NA	NA	N	0,51	P	0,81	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4630	4630	A	C	MI.13091	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	161	54	E	A	gAa/gCa	5,09	1	0	probably_damaging	1	neutral	0,6	neutral	4,46	deleterious	-3,2	deleterious	-5,6	high_impact	4,08	neutral	0,89	damaging	0,15	deleterious	3,45	23	0,04	0,35	disease	0,59	disease	0,75	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,31	high_impact	2,29	0,29	0,8	NA	NA	N	0,55	P	0,73	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4630	4630	A	G	MI.13092	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	161	54	E	G	gAa/gGa	5,09	1	0	probably_damaging	1	neutral	0,3	neutral	4,38	deleterious	-4,32	deleterious	-6,53	high_impact	3,74	neutral	0,83	damaging	0,15	deleterious	4,06	23,7	0,04	0,35	disease	0,78	disease	0,85	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0	high_impact	2	0,22	0,8	NA	NA	P	0,57	P	0,45	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4631	4631	A	T	MI.13093	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	162	54	E	D	gaA/gaT	8,55	1	0	probably_damaging	1	neutral	0,26	neutral	4,41	deleterious	-3,41	deleterious	-2,8	medium_impact	3,04	neutral	0,84	damaging	0,11	deleterious	3,73	23,3	0,17	0,45	disease	0,76	disease	0,81	disease	0,51	disease	0,66	3	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,04	medium_impact	1,42	0,55	0,8	NA	NA	P	0,56	P	0,85	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4631	4631	A	C	MI.13094	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	162	54	E	D	gaA/gaC	8,55	1	0	probably_damaging	1	neutral	0,26	neutral	4,41	deleterious	-3,41	deleterious	-2,8	medium_impact	3,04	neutral	0,84	damaging	0,11	deleterious	3,59	23,2	0,17	0,45	disease	0,76	disease	0,81	disease	0,51	disease	0,66	3	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,04	medium_impact	1,42	0,55	0,8	NA	NA	P	0,55	P	0,85	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4632	4632	G	C	MI.13095	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	163	55	A	P	Gct/Cct	3,25	1	0	probably_damaging	1	neutral	0,1	neutral	4,2	deleterious	-6,22	deleterious	-4,66	medium_impact	2,9	neutral	0,94	neutral	0,44	deleterious	3,69	23,3	0,02	0,35	disease	0,91	disease	0,92	disease	0,74	disease	0,68	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,93	low_impact	-3,54	medium_impact	-0,32	medium_impact	1,3	0,36	0,8	0,58	7,14	P	0,59	P	0,94	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4632	4632	G	A	MI.13096	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	163	55	A	T	Gct/Act	3,25	1	0	probably_damaging	1	neutral	0,19	neutral	4,21	deleterious	-4,91	deleterious	-3,73	medium_impact	2,4	neutral	0,87	neutral	0,39	deleterious	4,14	23,8	0,04	0,35	disease	0,81	disease	0,88	disease	0,62	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,9	low_impact	-3,54	medium_impact	-0,14	medium_impact	0,88	0,68	0,85	0,58	7,14	N	0,54	P	0,71	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4632	4632	G	T	MI.13097	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	163	55	A	S	Gct/Tct	3,25	1	0	probably_damaging	1	neutral	0,51	neutral	4,36	deleterious	-3,59	deleterious	-2,8	low_impact	1,08	neutral	0,86	neutral	0,75	deleterious	2,35	18,5	0,07	0,35	disease	0,78	disease	0,8	neutral	0,27	neutral	0,27	5	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,89	low_impact	-3,54	medium_impact	0,22	medium_impact	-0,24	0,44	0,8	0,58	7,14	N	0,4	N	0,39	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4633	4633	C	G	MI.13098	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	164	55	A	G	gCt/gGt	4,17	1	0	probably_damaging	1	neutral	0,15	neutral	4,23	deleterious	-3,93	deleterious	-3,73	medium_impact	2,45	neutral	0,95	neutral	0,58	deleterious	3,81	23,4	0,04	0,35	disease	0,85	disease	0,86	neutral	0,49	disease	0,64	3	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,88	low_impact	-3,54	medium_impact	-0,21	medium_impact	0,92	0,55	0,8	0,58	7,14	P	0,68	P	0,6	polymorphism	1	0,06	.	.	.	.	.	.	.	.	0,3	C4633G	LHON candidate	+	-	Reported	1
chrM	4633	4633	C	A	MI.13099	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	164	55	A	D	gCt/gAt	4,17	1	0	probably_damaging	1	neutral	0,09	neutral	4,2	deleterious	-5,86	deleterious	-5,6	high_impact	3,87	neutral	0,85	neutral	0,4	deleterious	4,4	24,1	0,02	0,35	disease	0,93	disease	0,94	disease	0,73	disease	0,67	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,92	low_impact	-3,54	medium_impact	-0,35	high_impact	2,11	0,3	0,8	0,58	7,14	P	0,62	P	0,96	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8587	8587	G	C	MI.131	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	61	21	V	L	Gta/Cta	-8,2	0	0	benign	0,19	neutral	0,58	neutral	4,6	neutral	1,18	neutral	-0,64	neutral_impact	-1,18	neutral	0,91	neutral	0,96	neutral	-0,64	0,1	0,48	0,65	neutral	0,32	neutral	0,16	neutral	0,21	neutral	0,27	5	neutral	0,31	deleterious	0,7	neutral	-6	neutral	0,19	medium_impact	-0,16	medium_impact	0,37	low_impact	-2,11	0,64	0,9	22,57	20,88	N	0,38	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9140	9140	C	G	MI.1310	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	614	205	A	G	gCt/gGt	6,14	1	0	probably_damaging	0,99	neutral	0,21	neutral	4,31	neutral	-1,67	deleterious	-3,13	low_impact	1,94	damaging	0,59	neutral	0,68	deleterious	4,05	23,7	0,26	0,65	NA	NA	disease	0,85	disease	0,51	neutral	0,49	0	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,87	low_impact	-2,65	medium_impact	-0,03	medium_impact	0,57	0,71	0,9	15,93	18,3	N	0,47	N	0,86	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4633	4633	C	T	MI.13100	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	164	55	A	V	gCt/gTt	4,17	1	0	probably_damaging	1	neutral	0,19	neutral	4,21	deleterious	-4,75	deleterious	-3,73	medium_impact	3,17	neutral	0,88	neutral	0,44	deleterious	4,21	23,9	0,03	0,35	disease	0,79	disease	0,88	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,89	low_impact	-3,54	medium_impact	-0,14	medium_impact	1,52	0,65	0,8	0,58	7,14	P	0,62	P	0,82	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4635	4635	G	A	MI.13101	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	166	56	A	T	Gcc/Acc	-8,72	0	0	possibly_damaging	0,87	neutral	0,81	neutral	4,51	deleterious	-3,35	deleterious	-2,54	low_impact	1,03	neutral	0,87	neutral	0,46	deleterious	2,86	21,7	0,08	0,35	neutral	0,28	disease	0,51	neutral	0,32	neutral	0,27	5	neutral	0,85	deleterious	0,47	neutral	-3	deleterious	0,7	low_impact	-1,55	medium_impact	0,56	medium_impact	-0,28	0,68	0,85	0,29	7,4	N	0,29	N	0,7	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4635	4635	G	T	MI.13102	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	166	56	A	S	Gcc/Tcc	-8,72	0	0	benign	0,39	neutral	0,86	neutral	4,74	neutral	-2,51	neutral	-1,49	neutral_impact	0,53	neutral	0,86	neutral	0,92	deleterious	2,06	16,62	0,15	0,45	neutral	0,31	disease	0,62	neutral	0,33	neutral	0,21	6	neutral	0,28	deleterious	0,74	neutral	-6	deleterious	0,56	medium_impact	-0,62	medium_impact	0,65	medium_impact	-0,7	0,5	0,8	0,29	7,4	N	0,23	N	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4635	4635	G	C	MI.13103	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	166	56	A	P	Gcc/Ccc	-8,72	0	0	probably_damaging	0,99	neutral	0,13	neutral	4,4	deleterious	-6,09	deleterious	-3,91	medium_impact	3,17	neutral	0,76	damaging	0,11	deleterious	3,74	23,3	0,03	0,35	neutral	0,24	disease	0,92	disease	0,68	disease	0,73	5	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,81	low_impact	-2,62	medium_impact	-0,25	medium_impact	1,52	0,43	0,8	0,29	7,4	N	0,32	N	0,93	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4636	4636	C	A	MI.13104	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	167	56	A	D	gCc/gAc	-0,2	0	0	probably_damaging	0,97	neutral	0,26	neutral	4,41	deleterious	-5,61	deleterious	-4,42	high_impact	3,51	neutral	0,83	damaging	0,12	deleterious	4,35	24,1	0,02	0,35	disease	0,65	disease	0,93	disease	0,66	disease	0,75	5	neutral	0,98	neutral	0,15	deleterious	2	deleterious	0,87	low_impact	-2,18	medium_impact	-0,04	medium_impact	1,81	0,26	0,8	0,29	7,4	N	0,31	N	0,98	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4636	4636	C	T	MI.13105	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	167	56	A	V	gCc/gTc	-0,2	0	0	probably_damaging	0,96	neutral	0,24	neutral	4,47	deleterious	-4,7	deleterious	-3,35	medium_impact	2,54	neutral	0,88	damaging	0,18	deleterious	4,34	24,1	0,06	0,35	neutral	0,33	disease	0,83	disease	0,57	disease	0,68	4	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,78	low_impact	-2,06	medium_impact	-0,07	medium_impact	0,99	0,69	0,85	0,29	7,4	N	0,38	N	0,82	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4636	4636	C	G	MI.13106	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	167	56	A	G	gCc/gGc	-0,2	0	0	possibly_damaging	0,87	neutral	0,23	neutral	4,63	neutral	-1,6	deleterious	-3,07	medium_impact	1,94	neutral	0,89	damaging	0,22	deleterious	3,83	23,4	0,13	0,4	disease	0,63	disease	0,83	disease	0,52	disease	0,69	4	neutral	0,91	neutral	0,18	NA	0	deleterious	0,79	low_impact	-1,55	medium_impact	-0,08	medium_impact	0,49	0,58	0,8	0,29	7,4	N	0,43	N	0,49	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4638	4638	A	T	MI.13107	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	169	57	I	F	Atc/Ttc	-10,33	0	0,01	possibly_damaging	0,55	neutral	0,45	neutral	4,61	neutral	-1,18	neutral	-1	low_impact	1,68	neutral	0,86	neutral	0,51	deleterious	3,38	23	0,15	0,4	disease	0,68	disease	0,79	disease	0,57	disease	0,72	4	neutral	0,57	neutral	0,45	neutral	-3	deleterious	0,69	medium_impact	-0,88	medium_impact	0,16	medium_impact	0,27	0,57	0,8	0,86	7,85	N	0,27	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4638	4638	A	G	MI.13108	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	169	57	I	V	Atc/Gtc	-10,33	0	0,01	benign	0,06	neutral	0,38	neutral	4,57	neutral	-0,33	neutral	0,82	neutral_impact	0,42	neutral	0,96	neutral	0,93	deleterious	0	2,56	0,29	0,45	neutral	0,45	neutral	0,39	neutral	0,46	neutral	0,43	1	neutral	0,58	deleterious	0,66	neutral	-6	neutral	0,21	medium_impact	0,3	medium_impact	0,09	medium_impact	-0,79	0,32	0,8	0,86	7,85	N	0,37	N	0,59	polymorphism	1	0,01	rs878960801	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4638	4638	A	C	MI.13109	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	169	57	I	L	Atc/Ctc	-10,33	0	0,01	benign	0,06	neutral	0,61	neutral	4,79	neutral	0,74	neutral	-0,07	neutral_impact	0,51	neutral	0,88	neutral	0,48	deleterious	1,83	15,17	0,19	0,45	neutral	0,41	disease	0,6	neutral	0,5	neutral	0,48	0	neutral	0,32	deleterious	0,78	neutral	-6	neutral	0,27	medium_impact	0,3	medium_impact	0,32	medium_impact	-0,72	0,51	0,8	0,86	7,85	N	0,25	N	0,56	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9142	9142	G	C	MI.1311	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	616	206	V	L	Gtc/Ctc	-10,05	0	0	benign	0,19	deleterious	0	neutral	3,75	deleterious	-3,62	deleterious	-2,62	high_impact	4,15	neutral	0,61	neutral	0,59	deleterious	3,68	23,3	0,31	0,65	NA	NA	disease	0,88	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,41	deleterious	2	neutral	0,38	medium_impact	-0,16	low_impact	-1,4	high_impact	2,46	0,54	0,9	48,23	8,69	N	0,43	N	0,72	disease_causing	0,65	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4639	4639	T	G	MI.13110	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	170	57	I	S	aTc/aGc	3,25	0,07	0,03	benign	0,14	neutral	0,87	neutral	4,5	neutral	-2,24	neutral	1,69	medium_impact	2,04	neutral	0,87	neutral	0,6	deleterious	2,33	18,39	0,05	0,35	neutral	0,48	disease	0,82	disease	0,56	disease	0,71	4	neutral	0,06	deleterious	0,87	neutral	-3	neutral	0,39	medium_impact	-0,08	medium_impact	0,67	medium_impact	0,57	0,33	0,8	0,86	7,85	N	0,25	N	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4639	4639	T	C	MI.13111	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	170	57	I	T	aTc/aCc	3,25	0,07	0,03	benign	0	neutral	1	neutral	4,55	neutral	-1,31	neutral	5,01	neutral_impact	-0,78	neutral	0,93	neutral	0,93	neutral	-1,36	0	0,11	0,4	neutral	0,33	neutral	0,11	neutral	0,27	neutral	0,23	5	neutral	0	deleterious	1	neutral	-6	neutral	0,12	medium_impact	1,95	high_impact	1,87	low_impact	-1,8	0,35	0,8	0,86	7,85	N	0,27	N	0,01	polymorphism	1	0,01	rs41510547	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4639	4639	T	A	MI.13112	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	170	57	I	N	aTc/aAc	3,25	0,07	0,03	benign	0,27	neutral	0,15	neutral	4,47	deleterious	-3,33	neutral	0,67	medium_impact	2,17	neutral	0,88	neutral	0,47	deleterious	2,64	20,4	0,12	0,4	disease	0,77	disease	0,89	disease	0,57	disease	0,74	5	neutral	0,82	neutral	0,44	neutral	-3	deleterious	0,62	medium_impact	-0,4	medium_impact	-0,21	medium_impact	0,68	0,38	0,8	0,86	7,85	N	0,46	N	0,69	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4640	4640	C	A	MI.13113	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	171	57	I	M	atC/atA	-0,2	0	0,02	possibly_damaging	0,73	neutral	0,2	neutral	4,62	neutral	-0,6	neutral	-0,07	neutral_impact	0,54	neutral	0,9	neutral	0,65	deleterious	3,48	23,1	0,28	0,45	disease	0,67	disease	0,61	neutral	0,44	neutral	0,41	2	neutral	0,85	neutral	0,24	neutral	-3	deleterious	0,7	low_impact	-1,19	medium_impact	-0,13	medium_impact	-0,69	0,68	0,85	0,86	7,85	P	0,57	P	0,67	disease_causing_automatic	0	0,01	rs387906426	Pathogenic	Leber's_optic_atrophy	RCV000010366.2	MedGen:OMIM:SNOMED_CT	.	.	CPD	0,3	C4640A	LHON	+	-	Reported	4
chrM	4640	4640	C	G	MI.13114	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	171	57	I	M	atC/atG	-0,2	0	0,02	possibly_damaging	0,73	neutral	0,2	neutral	4,62	neutral	-0,6	neutral	-0,07	neutral_impact	0,54	neutral	0,9	neutral	0,65	deleterious	3	22,2	0,28	0,45	disease	0,67	disease	0,61	neutral	0,44	neutral	0,41	2	neutral	0,85	neutral	0,24	neutral	-3	deleterious	0,7	low_impact	-1,19	medium_impact	-0,13	medium_impact	-0,69	0,68	0,85	0,86	7,85	N	0,53	P	0,67	disease_causing_automatic	0	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4641	4641	A	G	MI.13115	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	172	58	K	E	Aag/Gag	-7,8	0	0	probably_damaging	1	neutral	0,26	neutral	4,31	deleterious	-3,75	deleterious	-3,73	high_impact	4,08	neutral	0,87	damaging	0,12	deleterious	3,93	23,5	0,07	0,35	disease	0,69	disease	0,83	disease	0,76	disease	0,72	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,04	high_impact	2,29	0,55	0,8	NA	NA	N	0,44	N	0,91	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4641	4641	A	C	MI.13116	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	172	58	K	Q	Aag/Cag	-7,8	0	0	probably_damaging	1	neutral	0,29	neutral	4,3	deleterious	-3,82	deleterious	-3,73	high_impact	3,73	neutral	0,86	damaging	0,12	deleterious	3,35	22,9	0,13	0,4	disease	0,71	disease	0,81	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,01	medium_impact	2	0,64	0,8	NA	NA	N	0,35	N	0,88	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4642	4642	A	C	MI.13117	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	173	58	K	T	aAg/aCg	8,55	1	0	probably_damaging	1	neutral	0,38	neutral	4,3	deleterious	-4,19	deleterious	-5,6	medium_impact	3,1	neutral	0,85	damaging	0,12	deleterious	3,58	23,2	0,07	0,35	disease	0,56	disease	0,81	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,09	medium_impact	1,47	0,4	0,8	NA	NA	N	0,57	P	0,81	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4642	4642	A	T	MI.13118	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	173	58	K	M	aAg/aTg	8,55	1	0	probably_damaging	1	neutral	0,22	neutral	4,29	deleterious	-6,21	deleterious	-5,6	medium_impact	2,92	neutral	0,87	damaging	0,12	deleterious	3,91	23,5	0,04	0,35	disease	0,64	disease	0,81	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,1	medium_impact	1,31	0,39	0,8	NA	NA	N	0,56	P	0,45	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4643	4643	G	T	MI.13119	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	174	58	K	N	aaG/aaT	6,94	1	0	probably_damaging	1	neutral	0,29	neutral	4,3	deleterious	-4,41	deleterious	-4,67	medium_impact	3,27	neutral	0,88	damaging	0,11	deleterious	3,93	23,5	0,12	0,4	disease	0,73	disease	0,83	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,61	0,38	0,8	NA	NA	P	0,61	P	0,69	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9142	9142	G	T	MI.1312	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	616	206	V	F	Gtc/Ttc	-10,05	0	0	possibly_damaging	0,8	deleterious	0	neutral	3,68	deleterious	-5,18	deleterious	-4,4	high_impact	4,5	neutral	0,61	neutral	0,54	deleterious	3,97	23,6	0,14	0,65	NA	NA	disease	0,95	disease	0,74	disease	0,87	7	deleterious	1	neutral	0,1	deleterious	5	deleterious	0,81	low_impact	-1,33	low_impact	-1,4	high_impact	2,76	0,6	0,9	48,23	8,69	N	0,49	N	1	disease_causing	0,95	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4643	4643	G	C	MI.13120	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	174	58	K	N	aaG/aaC	6,94	1	0	probably_damaging	1	neutral	0,29	neutral	4,3	deleterious	-4,41	deleterious	-4,67	medium_impact	3,27	neutral	0,88	damaging	0,11	deleterious	3,83	23,4	0,12	0,4	disease	0,73	disease	0,83	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,61	0,38	0,8	NA	NA	P	0,61	P	0,69	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4644	4644	T	G	MI.13121	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	175	59	Y	D	Tat/Gat	0,49	0,99	0	probably_damaging	1	neutral	0,08	neutral	4,3	deleterious	-7,78	deleterious	-9,33	high_impact	4,12	neutral	0,88	damaging	0,13	deleterious	3,84	23,4	0,01	0,35	disease	0,64	disease	0,89	disease	0,81	disease	0,74	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,38	high_impact	2,32	0,15	0,8	0,29	6,97	P	0,57	P	0,96	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4644	4644	T	A	MI.13122	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	175	59	Y	N	Tat/Aat	0,49	0,99	0	probably_damaging	1	neutral	0,07	neutral	4,3	deleterious	-6,82	deleterious	-8,39	high_impact	3,77	neutral	0,87	damaging	0,15	deleterious	4,12	23,8	0,02	0,35	disease	0,64	disease	0,87	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	-0,42	high_impact	2,03	0,22	0,8	0,29	6,97	N	0,53	P	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4644	4644	T	C	MI.13123	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	175	59	Y	H	Tat/Cat	0,49	0,99	0	probably_damaging	1	neutral	0,12	neutral	4,3	deleterious	-6,77	deleterious	-4,66	high_impact	3,77	neutral	0,86	damaging	0,12	deleterious	3,56	23,1	0,05	0,35	disease	0,77	disease	0,78	disease	0,82	disease	0,71	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,27	high_impact	2,03	0,26	0,8	0,29	6,97	N	0,54	P	0,99	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4645	4645	A	G	MI.13124	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	176	59	Y	C	tAt/tGt	7,4	1	0	probably_damaging	1	deleterious	0,04	neutral	4,3	deleterious	-7,17	deleterious	-8,4	high_impact	4,12	neutral	0,85	damaging	0,11	deleterious	3,44	23	0,02	0,35	disease	0,85	disease	0,86	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-3,54	medium_impact	-0,56	high_impact	2,32	0,19	0,8	0,29	6,97	P	0,65	P	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4645	4645	A	C	MI.13125	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	176	59	Y	S	tAt/tCt	7,4	1	0	probably_damaging	1	neutral	0,2	neutral	4,33	deleterious	-5,86	deleterious	-8,39	high_impact	3,57	neutral	0,9	damaging	0,19	deleterious	3,61	23,2	0,02	0,35	neutral	0,49	disease	0,87	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	-0,13	medium_impact	1,86	0,28	0,8	0,29	6,97	P	0,62	P	0,96	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4645	4645	A	T	MI.13126	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	176	59	Y	F	tAt/tTt	7,4	1	0	probably_damaging	1	neutral	0,33	neutral	4,42	neutral	-2,71	deleterious	-3,73	high_impact	4,12	neutral	0,83	damaging	0,12	deleterious	3,33	22,9	0,13	0,4	disease	0,77	disease	0,82	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	0,04	high_impact	2,32	0,44	0,8	0,29	6,97	P	0,66	P	0,8	polymorphism	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4647	4647	T	G	MI.13127	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	178	60	F	V	Ttc/Gtc	-2,04	0	0	probably_damaging	1	neutral	0,09	neutral	4,41	neutral	-1,83	deleterious	-6,49	high_impact	4,09	neutral	0,76	damaging	0,15	deleterious	4,03	23,7	0,03	0,35	disease	0,66	disease	0,87	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	-0,35	high_impact	2,3	0,22	0,8	NA	NA	N	0,37	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4647	4647	T	C	MI.13128	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	178	60	F	L	Ttc/Ctc	-2,04	0	0	probably_damaging	1	neutral	0,3	neutral	4,47	neutral	-1	deleterious	-5,55	medium_impact	2,55	neutral	0,91	neutral	0,55	deleterious	4,02	23,6	0,04	0,35	neutral	0,2	disease	0,8	disease	0,6	disease	0,56	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0	medium_impact	1	0,4	0,8	NA	NA	N	0,46	N	0,91	polymorphism	1	0,1	rs879192007	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4647	4647	T	A	MI.13129	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	178	60	F	I	Ttc/Atc	-2,04	0	0	probably_damaging	1	neutral	0,09	neutral	4,46	neutral	-2,15	deleterious	-5,56	high_impact	4,09	neutral	0,91	damaging	0,15	deleterious	4,42	24,2	0,05	0,35	disease	0,65	disease	0,84	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	-0,35	high_impact	2,3	0,28	0,8	NA	NA	N	0,44	N	0,93	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9142	9142	G	A	MI.1313	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	616	206	V	I	Gtc/Atc	-10,05	0	0	benign	0,03	neutral	0,06	neutral	4,04	neutral	-1,16	neutral	-0,85	medium_impact	2,31	neutral	0,64	neutral	0,63	deleterious	3,69	23,3	0,37	0,65	NA	NA	disease	0,7	disease	0,62	disease	0,5	0	neutral	0,94	deleterious	0,52	neutral	-3	neutral	0,27	medium_impact	0,68	medium_impact	-0,38	medium_impact	0,88	0,74	0,9	48,23	8,69	N	0,4	N	0,06	polymorphism	0,64	0,06	rs200660596	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4648	4648	T	G	MI.13130	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	179	60	F	C	tTc/tGc	5,55	1	0	probably_damaging	1	neutral	0,05	neutral	4,27	deleterious	-5,31	deleterious	-7,43	high_impact	3,75	neutral	0,81	damaging	0,13	deleterious	3,92	23,5	0,02	0,35	disease	0,91	disease	0,86	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	-0,5	high_impact	2,01	0,15	0,8	NA	NA	P	0,6	P	0,99	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4648	4648	T	C	MI.13131	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	179	60	F	S	tTc/tCc	5,55	1	0	probably_damaging	1	neutral	0,13	neutral	4,3	deleterious	-3,78	deleterious	-7,44	high_impact	3,75	neutral	0,87	damaging	0,17	deleterious	4,05	23,7	0,01	0,35	neutral	0,32	disease	0,88	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	-0,25	high_impact	2,01	0,16	0,8	NA	NA	P	0,63	P	0,95	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	T4648C	PEG	+	-	Reported	1
chrM	4648	4648	T	A	MI.13132	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	179	60	F	Y	tTc/tAc	5,55	1	0	probably_damaging	1	neutral	0,42	neutral	4,37	deleterious	-3,85	deleterious	-2,79	medium_impact	2,77	neutral	0,83	damaging	0,12	deleterious	4,05	23,7	0,07	0,35	disease	0,71	disease	0,8	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,13	medium_impact	1,19	0,3	0,8	NA	NA	N	0,56	P	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4649	4649	C	A	MI.13133	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	180	60	F	L	ttC/ttA	5,78	1	0	probably_damaging	1	neutral	0,3	neutral	4,47	neutral	-1	deleterious	-5,55	medium_impact	2,55	neutral	0,91	neutral	0,55	deleterious	4,55	24,4	0,04	0,35	neutral	0,2	disease	0,8	disease	0,6	disease	0,56	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0	medium_impact	1	0,4	0,8	NA	NA	P	0,6	P	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4649	4649	C	G	MI.13134	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	180	60	F	L	ttC/ttG	5,78	1	0	probably_damaging	1	neutral	0,3	neutral	4,47	neutral	-1	deleterious	-5,55	medium_impact	2,55	neutral	0,91	neutral	0,55	deleterious	4,22	23,9	0,04	0,35	neutral	0,2	disease	0,8	disease	0,6	disease	0,56	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0	medium_impact	1	0,4	0,8	NA	NA	P	0,6	P	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4650	4650	C	G	MI.13135	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	181	61	L	V	Ctc/Gtc	-4,35	0	0	probably_damaging	1	neutral	0,19	neutral	4,25	neutral	-0,97	deleterious	-2,65	medium_impact	2,4	neutral	0,95	damaging	0,28	deleterious	3,28	22,8	0,14	0,4	neutral	0,48	disease	0,64	disease	0,55	disease	0,62	2	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,14	medium_impact	0,88	0,56	0,8	NA	NA	N	0,4	N	0,2	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4650	4650	C	A	MI.13136	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	181	61	L	I	Ctc/Atc	-4,35	0	0	probably_damaging	1	neutral	0,28	neutral	4,22	neutral	-0,9	neutral	-1,79	low_impact	1,63	neutral	0,94	neutral	0,37	deleterious	2,86	21,7	0,17	0,45	disease	0,53	disease	0,62	neutral	0,39	neutral	0,22	6	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,78	low_impact	-3,54	medium_impact	-0,02	medium_impact	0,23	0,48	0,8	NA	NA	N	0,36	N	0,48	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4650	4650	C	T	MI.13137	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	181	61	L	F	Ctc/Ttc	-4,35	0	0	probably_damaging	1	neutral	0,4	neutral	4,21	deleterious	-3,22	deleterious	-3,54	medium_impact	2,48	neutral	0,95	damaging	0,17	deleterious	3,81	23,4	0,07	0,35	neutral	0,23	disease	0,76	disease	0,58	disease	0,57	1	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,11	medium_impact	0,94	0,46	0,8	NA	NA	N	0,3	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4651	4651	T	C	MI.13138	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	182	61	L	P	cTc/cCc	-1,35	0	0	probably_damaging	1	deleterious	0,02	neutral	4,07	deleterious	-5,54	deleterious	-6,31	high_impact	3,56	neutral	0,85	damaging	0,11	deleterious	3,76	23,3	0,01	0,35	disease	0,86	disease	0,84	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-3,54	medium_impact	-0,73	medium_impact	1,85	0,37	0,8	NA	NA	N	0,32	N	0,94	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4651	4651	T	A	MI.13139	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	182	61	L	H	cTc/cAc	-1,35	0	0	probably_damaging	1	neutral	0,06	neutral	4,07	deleterious	-5,51	deleterious	-6,29	high_impact	3,9	neutral	0,88	damaging	0,1	deleterious	3,99	23,6	0,02	0,35	disease	0,85	disease	0,8	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	-0,46	high_impact	2,14	0,36	0,8	NA	NA	N	0,39	N	0,85	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9143	9143	T	G	MI.1314	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	617	206	V	G	gTc/gGc	6,14	1	0	possibly_damaging	0,83	deleterious	0	neutral	3,66	deleterious	-6,16	deleterious	-6,21	high_impact	4,5	neutral	0,65	neutral	0,66	deleterious	3,89	23,5	0,16	0,65	NA	NA	disease	0,91	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	5	deleterious	0,82	low_impact	-1,41	low_impact	-1,4	high_impact	2,76	0,45	0,9	48,23	8,69	N	0,48	N	0,95	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4651	4651	T	G	MI.13140	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	182	61	L	R	cTc/cGc	-1,35	0	0	probably_damaging	1	deleterious	0,04	neutral	4,07	deleterious	-4,98	deleterious	-5,37	high_impact	3,9	neutral	0,94	damaging	0,14	deleterious	4,03	23,6	0,01	0,35	disease	0,81	disease	0,89	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,9	low_impact	-3,54	medium_impact	-0,56	high_impact	2,14	0,24	0,8	NA	NA	N	0,47	N	0,97	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4653	4653	A	C	MI.13141	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	184	62	T	P	Acg/Ccg	-11,25	0	0	possibly_damaging	0,55	neutral	0,2	neutral	4,5	neutral	-2,9	deleterious	-4,47	medium_impact	2,21	neutral	0,75	neutral	0,35	deleterious	3,26	22,8	0,04	0,35	disease	0,93	disease	0,92	disease	0,7	disease	0,67	3	neutral	0,79	neutral	0,33	NA	0	deleterious	0,8	medium_impact	-0,88	medium_impact	-0,13	medium_impact	0,72	0,35	0,8	NA	NA	N	0,31	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4653	4653	A	T	MI.13142	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	184	62	T	S	Acg/Tcg	-11,25	0	0	benign	0,14	neutral	0,4	neutral	4,54	neutral	-1,03	deleterious	-2,98	medium_impact	2,81	neutral	0,89	neutral	0,54	neutral	1,51	13,38	0,32	0,5	disease	0,86	disease	0,77	disease	0,54	disease	0,66	3	neutral	0,53	deleterious	0,63	neutral	-3	neutral	0,42	medium_impact	-0,08	medium_impact	0,11	medium_impact	1,22	0,7	0,85	NA	NA	N	0,33	N	0,62	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4653	4653	A	G	MI.13143	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	184	62	T	A	Acg/Gcg	-11,25	0	0	benign	0,01	neutral	0,52	neutral	4,56	neutral	-0,29	deleterious	-3,33	medium_impact	2,21	neutral	0,89	neutral	0,75	neutral	1,58	13,72	0,25	0,45	disease	0,72	disease	0,62	neutral	0,49	neutral	0,34	3	neutral	0,47	deleterious	0,76	neutral	-3	neutral	0,24	medium_impact	1,03	medium_impact	0,23	medium_impact	0,72	0,34	0,8	NA	NA	N	0,32	N	0,78	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4654	4654	C	A	MI.13144	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	185	62	T	K	aCg/aAg	0,72	0	0	benign	0,34	neutral	0,28	neutral	4,51	neutral	-2,38	deleterious	-4,41	high_impact	3,7	neutral	0,87	neutral	0,37	deleterious	4,07	23,7	0,04	0,35	disease	0,91	disease	0,91	disease	0,66	disease	0,67	3	neutral	0,66	deleterious	0,47	neutral	-2	deleterious	0,64	medium_impact	-0,53	medium_impact	-0,02	medium_impact	1,97	0,48	0,8	NA	NA	N	0,41	N	0,94	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4654	4654	C	T	MI.13145	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	185	62	T	M	aCg/aTg	0,72	0	0	benign	0,02	neutral	0,23	neutral	4,55	neutral	0,37	deleterious	-3,35	medium_impact	2,61	neutral	0,95	neutral	0,82	deleterious	2,66	20,5	0,06	0,35	disease	0,79	disease	0,81	disease	0,51	neutral	0,36	3	neutral	0,76	deleterious	0,61	neutral	-3	neutral	0,28	medium_impact	0,75	medium_impact	-0,08	medium_impact	1,05	0,5	0,8	NA	NA	N	0,37	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4656	4656	C	G	MI.13146	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	187	63	Q	E	Caa/Gaa	-12,63	0	0	probably_damaging	0,99	neutral	0,28	neutral	4,57	neutral	-0,89	deleterious	-2,8	high_impact	4,12	neutral	0,81	damaging	0,08	deleterious	2,92	21,9	0,16	0,45	disease	0,66	disease	0,82	disease	0,73	disease	0,71	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-2,62	medium_impact	-0,02	high_impact	2,32	0,49	0,8	NA	NA	N	0,31	N	0,9	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4656	4656	C	A	MI.13147	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	187	63	Q	K	Caa/Aaa	-12,63	0	0	probably_damaging	0,99	neutral	0,3	neutral	4,57	neutral	-0,94	deleterious	-3,73	high_impact	3,77	neutral	0,78	damaging	0,06	deleterious	3,84	23,4	0,08	0,35	disease	0,6	disease	0,91	disease	0,76	disease	0,74	5	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-2,62	medium_impact	0	high_impact	2,03	0,42	0,8	NA	NA	N	0,32	N	0,97	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4657	4657	A	C	MI.13148	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	188	63	Q	P	cAa/cCa	5,55	1	0	probably_damaging	1	neutral	0,2	neutral	4,5	deleterious	-3,01	deleterious	-5,6	high_impact	4,12	neutral	0,76	damaging	0,07	deleterious	3,25	22,8	0,03	0,35	disease	0,82	disease	0,91	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	-0,13	high_impact	2,32	0,32	0,8	NA	NA	P	0,68	P	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4657	4657	A	T	MI.13149	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	188	63	Q	L	cAa/cTa	5,55	1	0	probably_damaging	1	neutral	0,68	neutral	4,51	neutral	-2,45	deleterious	-6,53	high_impact	3,77	neutral	0,75	damaging	0,06	deleterious	3,71	23,3	0,03	0,35	neutral	0,22	disease	0,92	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,39	high_impact	2,03	0,28	0,8	NA	NA	N	0,52	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9143	9143	T	A	MI.1315	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	617	206	V	D	gTc/gAc	6,14	1	0	probably_damaging	0,94	deleterious	0	neutral	3,66	deleterious	-5,95	deleterious	-6,2	high_impact	4,5	neutral	0,66	neutral	0,56	deleterious	4,52	24,3	0,1	0,65	NA	NA	disease	0,94	disease	0,8	disease	0,86	7	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,89	low_impact	-1,89	low_impact	-1,4	high_impact	2,76	0,52	0,9	48,23	8,69	P	0,51	P	0,99	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4657	4657	A	G	MI.13150	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	188	63	Q	R	cAa/cGa	5,55	1	0	probably_damaging	0,99	neutral	0,35	neutral	4,53	neutral	-1,67	deleterious	-3,73	high_impact	4,12	neutral	0,83	damaging	0,07	deleterious	3,36	22,9	0,08	0,35	disease	0,66	disease	0,91	disease	0,77	disease	0,74	5	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,84	low_impact	-2,62	medium_impact	0,06	high_impact	2,32	0,31	0,8	NA	NA	P	0,68	P	0,87	polymorphism	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4658	4658	A	T	MI.13151	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	189	63	Q	H	caA/caT	8,55	1	0	probably_damaging	1	neutral	0,54	neutral	4,5	neutral	-2,79	deleterious	-4,67	high_impact	4,12	neutral	0,76	damaging	0,06	deleterious	3,48	23,1	0,08	0,35	disease	0,81	disease	0,84	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,25	high_impact	2,32	0,65	0,8	NA	NA	P	0,64	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4658	4658	A	C	MI.13152	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	189	63	Q	H	caA/caC	8,55	1	0	probably_damaging	1	neutral	0,54	neutral	4,5	neutral	-2,79	deleterious	-4,67	high_impact	4,12	neutral	0,76	damaging	0,06	deleterious	3,32	22,9	0,08	0,35	disease	0,81	disease	0,84	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,25	high_impact	2,32	0,65	0,8	NA	NA	P	0,63	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4659	4659	G	C	MI.13153	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	190	64	A	P	Gca/Cca	2,1	1	0,01	possibly_damaging	0,85	neutral	0,12	neutral	4,41	deleterious	-4,7	deleterious	-4,13	high_impact	3,86	neutral	0,84	neutral	0,42	deleterious	3,58	23,2	0,03	0,35	disease	0,85	disease	0,95	disease	0,76	disease	0,75	5	neutral	0,94	neutral	0,14	deleterious	1	deleterious	0,87	low_impact	-1,49	medium_impact	-0,27	high_impact	2,11	0,65	0,8	0,58	6,94	P	0,62	P	0,94	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4659	4659	G	T	MI.13154	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	190	64	A	S	Gca/Tca	2,1	1	0,01	benign	0,02	neutral	0,46	neutral	4,49	neutral	-1,34	neutral	-2,02	low_impact	1,24	neutral	0,87	neutral	0,9	deleterious	0,75	9,13	0,25	0,45	neutral	0,5	disease	0,86	disease	0,54	neutral	0,28	4	neutral	0,52	deleterious	0,72	neutral	-6	neutral	0,3	medium_impact	0,75	medium_impact	0,17	medium_impact	-0,1	0,65	0,8	0,58	6,94	N	0,39	N	0,14	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4659	4659	G	A	MI.13155	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	190	64	A	T	Gca/Aca	2,1	1	0,01	benign	0,06	neutral	0,3	neutral	4,45	neutral	-2,11	deleterious	-2,75	low_impact	1,76	neutral	0,9	neutral	0,73	neutral	1,11	11,29	0,13	0,4	disease	0,65	disease	0,87	neutral	0,44	neutral	0,22	6	neutral	0,67	deleterious	0,62	neutral	-6	neutral	0,32	medium_impact	0,3	medium_impact	0	medium_impact	0,34	0,71	0,85	0,58	6,94	P	0,61	P	0,71	polymorphism	1	0,06	.	.	.	.	.	.	.	.	2,67	G4659A	Possible PD risk factor	+	-	Reported	1
chrM	4660	4660	C	T	MI.13156	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	191	64	A	V	gCa/gTa	1,64	1	0	possibly_damaging	0,44	neutral	0,36	neutral	4,5	neutral	-2,15	deleterious	-3,36	medium_impact	2,39	neutral	0,95	neutral	0,57	deleterious	2,56	19,88	0,08	0,35	disease	0,54	disease	0,92	disease	0,58	disease	0,58	2	neutral	0,6	neutral	0,46	NA	0	deleterious	0,67	medium_impact	-0,7	medium_impact	0,07	medium_impact	0,87	0,79	0,85	0,58	6,94	N	0,56	P	0,8	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4660	4660	C	G	MI.13157	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	191	64	A	G	gCa/gGa	1,64	1	0	benign	0,33	neutral	0,21	neutral	4,48	neutral	-2,32	deleterious	-3,34	medium_impact	3,31	neutral	0,91	neutral	0,55	deleterious	2,16	17,22	0,19	0,45	disease	0,8	disease	0,91	disease	0,63	disease	0,68	4	neutral	0,75	neutral	0,44	neutral	-3	deleterious	0,6	medium_impact	-0,52	medium_impact	-0,11	medium_impact	1,64	0,71	0,85	0,58	6,94	P	0,55	P	0,47	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4660	4660	C	A	MI.13158	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	191	64	A	E	gCa/gAa	1,64	1	0	possibly_damaging	0,58	neutral	0,16	neutral	4,45	deleterious	-3,02	deleterious	-4,05	medium_impact	3,31	neutral	0,9	neutral	0,41	deleterious	4,06	23,7	0,02	0,35	disease	0,8	disease	0,95	disease	0,73	disease	0,78	6	neutral	0,84	neutral	0,29	NA	0	deleterious	0,77	medium_impact	-0,93	medium_impact	-0,19	medium_impact	1,64	0,41	0,8	0,58	6,94	P	0,59	P	0,88	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4662	4662	A	T	MI.13159	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	193	65	T	S	Acc/Tcc	-6,65	0	0	possibly_damaging	0,51	neutral	0,55	neutral	4,6	neutral	-1,1	deleterious	-3,45	low_impact	1,47	neutral	0,86	neutral	0,9	deleterious	2,58	19,96	0,35	0,5	neutral	0,26	disease	0,73	neutral	0,4	neutral	0,21	6	neutral	0,47	deleterious	0,52	neutral	-3	deleterious	0,54	medium_impact	-0,81	medium_impact	0,26	medium_impact	0,09	0,61	0,8	0,29	10,05	N	0,27	N	0,49	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9143	9143	T	C	MI.1316	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	617	206	V	A	gTc/gCc	6,14	1	0	benign	0,39	deleterious	0	neutral	3,77	deleterious	-4,02	deleterious	-3,52	high_impact	3,94	neutral	0,6	neutral	0,65	deleterious	3,65	23,2	0,26	0,65	NA	NA	disease	0,73	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,57	medium_impact	-0,57	low_impact	-1,4	high_impact	2,28	0,29	0,9	48,23	8,69	P	0,51	P	0,84	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4662	4662	A	C	MI.13160	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	193	65	T	P	Acc/Ccc	-6,65	0	0	probably_damaging	0,99	neutral	0,13	neutral	4,57	neutral	-2,65	deleterious	-5,44	medium_impact	3,36	neutral	0,76	neutral	0,42	deleterious	3,82	23,4	0,04	0,35	disease	0,84	disease	0,94	disease	0,73	disease	0,74	5	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,87	low_impact	-2,62	medium_impact	-0,25	medium_impact	1,68	0,32	0,8	0,29	10,05	N	0,34	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4662	4662	A	G	MI.13161	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	193	65	T	A	Acc/Gcc	-6,65	0	0	possibly_damaging	0,81	neutral	1	neutral	4,67	neutral	0,31	deleterious	-4,46	low_impact	0,88	neutral	0,84	neutral	0,61	deleterious	3,76	23,3	0,2	0,45	neutral	0,22	neutral	0,25	neutral	0,38	neutral	0,41	2	neutral	0,81	deleterious	0,6	neutral	-3	deleterious	0,63	low_impact	-1,37	high_impact	1,87	medium_impact	-0,4	0,31	0,8	0,29	10,05	N	0,24	N	0,83	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4663	4663	C	G	MI.13162	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	194	65	T	S	aCc/aGc	-0,43	0	0	possibly_damaging	0,51	neutral	0,55	neutral	4,6	neutral	-1,1	deleterious	-3,45	low_impact	1,47	neutral	0,86	neutral	0,9	deleterious	2,21	17,55	0,35	0,5	neutral	0,26	disease	0,73	neutral	0,4	neutral	0,21	6	neutral	0,47	deleterious	0,52	neutral	-3	deleterious	0,54	medium_impact	-0,81	medium_impact	0,26	medium_impact	0,09	0,61	0,8	0,29	10,05	N	0,26	N	0,49	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4663	4663	C	A	MI.13163	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	194	65	T	N	aCc/aAc	-0,43	0	0	probably_damaging	0,94	neutral	0,23	neutral	4,57	neutral	-2,35	deleterious	-4,46	medium_impact	3,01	neutral	0,88	neutral	0,55	deleterious	3,57	23,1	0,27	0,45	disease	0,81	disease	0,89	disease	0,61	disease	0,69	4	neutral	0,96	neutral	0,15	deleterious	1	deleterious	0,82	low_impact	-1,89	medium_impact	-0,08	medium_impact	1,39	0,51	0,8	0,29	10,05	N	0,38	N	0,88	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4663	4663	C	T	MI.13164	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	194	65	T	I	aCc/aTc	-0,43	0	0	probably_damaging	0,99	neutral	0,5	neutral	4,82	neutral	1,65	deleterious	-5,48	low_impact	1,18	neutral	0,9	neutral	0,56	deleterious	3,73	23,3	0,14	0,4	disease	0,79	disease	0,92	disease	0,58	disease	0,62	2	deleterious	0,98	neutral	0,26	neutral	-2	deleterious	0,83	low_impact	-2,62	medium_impact	0,21	medium_impact	-0,15	0,55	0,8	0,29	10,05	N	0,35	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4665	4665	G	T	MI.13165	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	196	66	A	S	Gca/Tca	-8,03	0	0	probably_damaging	1	neutral	0,51	neutral	4,87	neutral	1,14	deleterious	-2,8	low_impact	1,94	neutral	0,88	damaging	0,13	deleterious	3,56	23,1	0,13	0,4	neutral	0,34	disease	0,88	disease	0,55	disease	0,67	3	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,8	low_impact	-3,54	medium_impact	0,22	medium_impact	0,49	0,48	0,8	NA	NA	N	0,27	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4665	4665	G	C	MI.13166	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	196	66	A	P	Gca/Cca	-8,03	0	0	probably_damaging	1	neutral	0,11	neutral	4,44	deleterious	-3,89	deleterious	-4,67	high_impact	3,63	neutral	0,81	damaging	0,12	deleterious	3,73	23,3	0,03	0,35	disease	0,77	disease	0,93	disease	0,76	disease	0,75	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,88	low_impact	-3,54	medium_impact	-0,3	medium_impact	1,91	0,41	0,8	NA	NA	N	0,35	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4665	4665	G	A	MI.13167	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	196	66	A	T	Gca/Aca	-8,03	0	0	probably_damaging	1	neutral	0,28	neutral	4,47	neutral	-2,36	deleterious	-3,73	medium_impact	2,94	neutral	0,86	damaging	0,12	deleterious	4,07	23,7	0,08	0,35	disease	0,51	disease	0,87	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	-0,02	medium_impact	1,33	0,75	0,85	NA	NA	N	0,34	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4666	4666	C	A	MI.13168	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	197	66	A	E	gCa/gAa	7,17	1	0	probably_damaging	1	neutral	0,15	neutral	4,44	deleterious	-3,52	deleterious	-4,67	high_impact	3,98	neutral	0,89	damaging	0,13	deleterious	4,38	24,1	0,03	0,35	disease	0,71	disease	0,94	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	-0,21	high_impact	2,21	0,34	0,8	NA	NA	P	0,69	P	0,99	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4666	4666	C	T	MI.13169	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	197	66	A	V	gCa/gTa	7,17	1	0	probably_damaging	1	neutral	0,32	neutral	4,45	neutral	-2,87	deleterious	-3,73	high_impact	3,98	neutral	0,83	damaging	0,13	deleterious	4,35	24,1	0,06	0,35	neutral	0,17	disease	0,91	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,76	low_impact	-3,54	medium_impact	0,03	high_impact	2,21	0,74	0,85	NA	NA	P	0,58	P	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9145	9145	G	A	MI.1317	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	619	207	A	T	Gcc/Acc	-3,8	0	0,01	probably_damaging	1	deleterious	0,01	neutral	4,08	neutral	-2,7	deleterious	-3,54	medium_impact	3,17	damaging	0,58	neutral	0,48	deleterious	4,35	24,1	0,48	0,65	NA	NA	disease	0,87	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,89	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,62	0,84	0,9	48,67	8,68	N	0,34	N	0,8	disease_causing	0,57	0,27	.	.	.	.	.	.	COSM1155694	.	.	.	.	.	.	.	.
chrM	4666	4666	C	G	MI.13170	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	197	66	A	G	gCa/gGa	7,17	1	0	probably_damaging	1	neutral	0,24	neutral	5,03	neutral	1,64	deleterious	-3,73	low_impact	1,67	neutral	0,93	damaging	0,15	deleterious	3,83	23,4	0,14	0,4	disease	0,7	disease	0,89	disease	0,55	disease	0,66	3	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,07	medium_impact	0,26	0,59	0,8	NA	NA	P	0,57	P	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4668	4668	T	A	MI.13171	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	199	67	S	T	Tcc/Acc	-5,73	0	0	probably_damaging	1	neutral	0,32	neutral	3,79	deleterious	-5,14	deleterious	-2,8	high_impact	3,68	neutral	0,88	damaging	0,13	deleterious	3,68	23,3	0,1	0,4	neutral	0,45	disease	0,76	disease	0,62	disease	0,63	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,03	medium_impact	1,95	0,65	0,8	0,29	6,81	N	0,39	N	0,71	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4668	4668	T	G	MI.13172	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	199	67	S	A	Tcc/Gcc	-5,73	0	0	probably_damaging	1	neutral	1	neutral	3,86	deleterious	-3,42	deleterious	-2,8	low_impact	1,68	neutral	0,9	neutral	0,3	deleterious	2,46	19,18	0,12	0,4	disease	0,54	neutral	0,39	neutral	0,45	disease	0,5	0	deleterious	0,99	deleterious	0,5	neutral	-2	deleterious	0,74	low_impact	-3,54	high_impact	1,87	medium_impact	0,27	0,42	0,8	0,29	6,81	N	0,27	N	0,49	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4668	4668	T	C	MI.13173	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	199	67	S	P	Tcc/Ccc	-5,73	0	0	probably_damaging	1	neutral	0,15	neutral	3,77	deleterious	-6,27	deleterious	-4,67	high_impact	4,03	neutral	0,85	damaging	0,12	deleterious	3,85	23,4	0,03	0,35	disease	0,86	disease	0,92	disease	0,79	disease	0,73	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	-0,21	high_impact	2,25	0,3	0,8	0,29	6,81	N	0,46	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4669	4669	C	T	MI.13174	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	200	67	S	F	tCc/tTc	2,79	0,99	0	probably_damaging	1	neutral	0,73	neutral	3,76	deleterious	-7,72	deleterious	-5,6	high_impact	4,03	neutral	0,78	damaging	0,09	deleterious	4,05	23,7	0,03	0,35	disease	0,7	disease	0,94	disease	0,71	disease	0,8	6	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,45	high_impact	2,25	0,09	0,8	0,29	6,81	N	0,45	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4669	4669	C	A	MI.13175	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	200	67	S	Y	tCc/tAc	2,79	0,99	0	probably_damaging	1	neutral	0,75	neutral	3,76	deleterious	-7,44	deleterious	-5,6	high_impact	4,03	neutral	0,9	damaging	0,11	deleterious	4,03	23,6	0,03	0,35	disease	0,77	disease	0,92	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,47	high_impact	2,25	0,25	0,8	0,29	6,81	N	0,49	N	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4669	4669	C	G	MI.13176	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	200	67	S	C	tCc/tGc	2,79	0,99	0	probably_damaging	1	neutral	0,13	neutral	3,76	deleterious	-7,76	deleterious	-4,67	high_impact	4,03	neutral	0,87	damaging	0,13	deleterious	3,42	23	0,04	0,35	disease	0,83	disease	0,88	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,25	high_impact	2,25	0,26	0,8	0,29	6,81	N	0,57	P	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4671	4671	A	G	MI.13177	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	202	68	M	V	Ata/Gta	-10,79	0	0	possibly_damaging	0,56	neutral	0,4	neutral	4,81	neutral	1,08	deleterious	-3,51	low_impact	1,19	neutral	0,84	damaging	0,17	deleterious	2,58	19,95	0,31	0,5	disease	0,65	disease	0,81	disease	0,65	disease	0,72	4	neutral	0,61	neutral	0,42	neutral	-3	deleterious	0,68	medium_impact	-0,89	medium_impact	0,11	medium_impact	-0,14	0,36	0,8	1,15	7,52	N	0,24	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4671	4671	A	C	MI.13178	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	202	68	M	L	Ata/Cta	-10,79	0	0	benign	0,03	neutral	0,41	neutral	4,85	neutral	1,78	deleterious	-2,65	low_impact	1,23	neutral	0,92	damaging	0,17	deleterious	3,1	22,5	0,27	0,45	neutral	0,28	disease	0,85	disease	0,63	disease	0,74	5	neutral	0,56	deleterious	0,69	neutral	-6	neutral	0,23	medium_impact	0,59	medium_impact	0,12	medium_impact	-0,11	0,3	0,8	1,15	7,52	N	0,3	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4671	4671	A	T	MI.13179	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	202	68	M	L	Ata/Tta	-10,79	0	0	benign	0,03	neutral	0,41	neutral	4,85	neutral	1,78	deleterious	-2,65	low_impact	1,23	neutral	0,92	damaging	0,17	deleterious	3,24	22,8	0,27	0,45	neutral	0,28	disease	0,85	disease	0,63	disease	0,74	5	neutral	0,56	deleterious	0,69	neutral	-6	neutral	0,23	medium_impact	0,59	medium_impact	0,12	medium_impact	-0,11	0,3	0,8	1,15	7,52	N	0,3	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9145	9145	G	T	MI.1318	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	619	207	A	S	Gcc/Tcc	-3,8	0	0,01	probably_damaging	0,99	neutral	0,09	neutral	4,19	neutral	-1,21	deleterious	-2,65	low_impact	1,9	neutral	0,61	neutral	0,6	deleterious	3,78	23,4	0,36	0,65	NA	NA	disease	0,83	neutral	0,41	neutral	0,48	0	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,9	low_impact	-2,65	medium_impact	-0,28	medium_impact	0,53	0,84	0,9	48,67	8,68	N	0,36	N	0,95	polymorphism	0,64	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4672	4672	T	A	MI.13180	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	203	68	M	K	aTa/aAa	1,64	0,39	0	probably_damaging	0,93	neutral	0,19	neutral	4,63	neutral	-1,88	deleterious	-5,41	medium_impact	2,82	neutral	0,81	damaging	0,13	deleterious	3,8	23,4	0,04	0,35	disease	0,8	disease	0,93	disease	0,72	disease	0,73	5	neutral	0,96	neutral	0,13	deleterious	1	deleterious	0,87	low_impact	-1,83	medium_impact	-0,14	medium_impact	1,23	0,2	0,8	1,15	7,52	N	0,3	N	0,98	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4672	4672	T	C	MI.13181	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	203	68	M	T	aTa/aCa	1,64	0,39	0	possibly_damaging	0,85	neutral	0,28	neutral	4,7	neutral	0,41	deleterious	-5,35	neutral_impact	0,42	neutral	0,87	neutral	0,31	deleterious	2,77	21,2	0,15	0,4	disease	0,74	disease	0,55	neutral	0,48	neutral	0,3	4	neutral	0,88	neutral	0,22	neutral	-3	deleterious	0,76	low_impact	-1,49	medium_impact	-0,02	medium_impact	-0,79	0,15	0,8	1,15	7,52	N	0,35	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4673	4673	A	T	MI.13182	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	204	68	M	I	atA/atT	2,56	0,4	0	possibly_damaging	0,56	neutral	0,37	neutral	4,81	neutral	0,67	deleterious	-3,51	low_impact	0,88	neutral	0,9	neutral	0,36	deleterious	3,3	22,8	0,28	0,45	disease	0,69	disease	0,85	disease	0,58	disease	0,62	2	neutral	0,64	neutral	0,41	neutral	-3	deleterious	0,71	medium_impact	-0,89	medium_impact	0,08	medium_impact	-0,4	0,4	0,8	1,15	7,52	N	0,42	N	0,93	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4673	4673	A	C	MI.13183	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	204	68	M	I	atA/atC	2,56	0,4	0	possibly_damaging	0,56	neutral	0,37	neutral	4,81	neutral	0,67	deleterious	-3,51	low_impact	0,88	neutral	0,9	neutral	0,36	deleterious	3,24	22,8	0,28	0,45	disease	0,69	disease	0,85	disease	0,58	disease	0,62	2	neutral	0,64	neutral	0,41	neutral	-3	deleterious	0,71	medium_impact	-0,89	medium_impact	0,08	medium_impact	-0,4	0,4	0,8	1,15	7,52	N	0,41	N	0,93	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4674	4674	A	T	MI.13184	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	205	69	I	F	Atc/Ttc	-1,81	0	0,02	possibly_damaging	0,76	neutral	0,66	neutral	4,66	neutral	0,06	deleterious	-2,67	low_impact	1,62	neutral	0,88	neutral	0,5	deleterious	3,37	22,9	0,19	0,45	disease	0,61	disease	0,72	disease	0,58	disease	0,7	4	neutral	0,71	neutral	0,45	neutral	-3	deleterious	0,71	low_impact	-1,26	medium_impact	0,37	medium_impact	0,22	0,55	0,8	0,58	6,97	N	0,29	N	0,63	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4674	4674	A	G	MI.13185	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	205	69	I	V	Atc/Gtc	-1,81	0	0,02	benign	0,02	neutral	0,39	neutral	4,57	neutral	-0,08	neutral	-0,88	neutral_impact	0,67	neutral	0,99	neutral	0,92	neutral	-0,18	1,21	0,45	0,55	disease	0,52	neutral	0,27	neutral	0,35	neutral	0,32	4	neutral	0,59	deleterious	0,69	neutral	-6	neutral	0,13	medium_impact	0,75	medium_impact	0,1	medium_impact	-0,58	0,52	0,8	0,58	6,97	N	0,43	N	0,09	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4674	4674	A	C	MI.13186	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	205	69	I	L	Atc/Ctc	-1,81	0	0,02	benign	0,02	neutral	1	neutral	4,72	neutral	0,73	neutral	0,21	neutral_impact	0,01	neutral	0,88	neutral	0,92	neutral	-0,92	0,02	0,25	0,45	neutral	0,41	neutral	0,17	neutral	0,24	neutral	0,28	4	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,13	medium_impact	0,75	high_impact	1,87	low_impact	-1,14	0,5	0,8	0,58	6,97	N	0,29	N	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4675	4675	T	G	MI.13187	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	206	69	I	S	aTc/aGc	-1,58	0	0	possibly_damaging	0,81	neutral	0,56	neutral	4,48	neutral	-2,45	deleterious	-4,51	medium_impact	2,03	neutral	0,86	neutral	0,46	deleterious	3,79	23,4	0,05	0,35	disease	0,63	disease	0,7	disease	0,56	disease	0,69	4	neutral	0,78	neutral	0,38	NA	0	deleterious	0,7	low_impact	-1,37	medium_impact	0,27	medium_impact	0,56	0,34	0,8	0,58	6,97	N	0,21	N	0,85	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4675	4675	T	A	MI.13188	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	206	69	I	N	aTc/aAc	-1,58	0	0	probably_damaging	0,92	neutral	0,23	neutral	4,45	deleterious	-3,94	deleterious	-5,46	medium_impact	2,27	neutral	0,89	neutral	0,44	deleterious	4,4	24,1	0,14	0,4	disease	0,78	disease	0,78	disease	0,58	disease	0,74	5	neutral	0,95	neutral	0,16	deleterious	1	deleterious	0,79	low_impact	-1,77	medium_impact	-0,08	medium_impact	0,77	0,36	0,8	0,58	6,97	N	0,4	N	0,89	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4675	4675	T	C	MI.13189	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	206	69	I	T	aTc/aCc	-1,58	0	0	possibly_damaging	0,58	neutral	0,46	neutral	4,49	neutral	-2,12	deleterious	-3,6	neutral_impact	0,78	neutral	0,88	neutral	0,78	neutral	1,59	13,81	0,11	0,4	disease	0,67	neutral	0,44	neutral	0,37	disease	0,59	2	neutral	0,58	neutral	0,44	neutral	-3	deleterious	0,6	medium_impact	-0,93	medium_impact	0,17	medium_impact	-0,49	0,35	0,8	0,58	6,97	N	0,35	N	0,73	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9145	9145	G	C	MI.1319	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	619	207	A	P	Gcc/Ccc	-3,8	0	0,01	probably_damaging	1	deleterious	0,01	neutral	4,04	deleterious	-4,4	deleterious	-4,49	high_impact	4,32	damaging	0,42	neutral	0,44	deleterious	3,91	23,5	0,12	0,65	NA	NA	disease	0,94	disease	0,75	disease	0,85	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,94	low_impact	-3,6	medium_impact	-0,84	high_impact	2,6	0,74	0,9	48,67	8,68	P	0,57	P	0,97	disease_causing	0,82	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4676	4676	C	A	MI.13190	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	207	69	I	M	atC/atA	3,25	0,17	0	possibly_damaging	0,86	neutral	0,73	neutral	4,5	neutral	-1,7	neutral	-1,03	neutral_impact	0,72	neutral	0,88	neutral	0,95	deleterious	2,16	17,24	0,36	0,5	disease	0,59	neutral	0,27	neutral	0,28	disease	0,55	1	neutral	0,83	neutral	0,44	neutral	-3	deleterious	0,66	low_impact	-1,52	medium_impact	0,45	medium_impact	-0,54	0,58	0,8	0,58	6,97	N	0,33	N	0,64	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4676	4676	C	G	MI.13191	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	207	69	I	M	atC/atG	3,25	0,17	0	possibly_damaging	0,86	neutral	0,73	neutral	4,5	neutral	-1,7	neutral	-1,03	neutral_impact	0,72	neutral	0,88	neutral	0,95	neutral	1,69	14,36	0,36	0,5	disease	0,59	neutral	0,27	neutral	0,28	disease	0,55	1	neutral	0,83	neutral	0,44	neutral	-3	deleterious	0,66	low_impact	-1,52	medium_impact	0,45	medium_impact	-0,54	0,58	0,8	0,58	6,97	N	0,33	N	0,64	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4677	4677	C	A	MI.13192	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	208	70	L	I	Ctt/Att	-2,73	0	0	possibly_damaging	0,56	neutral	0,64	neutral	3,82	neutral	-2,77	neutral	-1,85	neutral_impact	0,52	neutral	0,9	neutral	0,88	neutral	1	10,64	0,2	0,45	NA	NA	neutral	0,25	neutral	0,25	neutral	0,19	6	neutral	0,49	deleterious	0,54	neutral	-3	deleterious	0,61	medium_impact	-0,89	medium_impact	0,35	medium_impact	-0,71	0,45	0,8	0,29	6,59	N	0,38	N	0,19	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4677	4677	C	T	MI.13193	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	208	70	L	F	Ctt/Ttt	-2,73	0	0	benign	0,06	neutral	0,28	neutral	3,77	deleterious	-3,15	deleterious	-3,57	low_impact	0,98	neutral	0,99	neutral	0,8	deleterious	0,73	9,04	0,13	0,4	NA	NA	disease	0,76	neutral	0,39	neutral	0,41	2	neutral	0,69	deleterious	0,61	neutral	-6	neutral	0,26	medium_impact	0,3	medium_impact	-0,02	medium_impact	-0,32	0,34	0,8	0,29	6,59	N	0,45	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4677	4677	C	G	MI.13194	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	208	70	L	V	Ctt/Gtt	-2,73	0	0	possibly_damaging	0,56	neutral	0,12	neutral	3,7	deleterious	-3,97	deleterious	-2,8	low_impact	1,6	neutral	0,89	neutral	0,75	deleterious	0,48	7,31	0,15	0,4	NA	NA	neutral	0,37	neutral	0,36	neutral	0,16	7	neutral	0,88	neutral	0,28	neutral	-3	deleterious	0,64	medium_impact	-0,89	medium_impact	-0,27	medium_impact	0,2	0,54	0,8	0,29	6,59	N	0,53	P	0,54	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4678	4678	T	C	MI.13195	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	209	70	L	P	cTt/cCt	-2,5	0	0	probably_damaging	0,97	deleterious	0,02	neutral	3,61	deleterious	-8,26	deleterious	-6,58	high_impact	3,5	neutral	0,83	neutral	0,34	deleterious	3,65	23,2	0,01	0,35	NA	NA	disease	0,92	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,9	low_impact	-2,18	medium_impact	-0,73	medium_impact	1,8	0,33	0,8	0,29	6,59	N	0,38	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4678	4678	T	A	MI.13196	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	209	70	L	H	cTt/cAt	-2,5	0	0	probably_damaging	0,97	neutral	0,05	neutral	3,61	deleterious	-8,63	deleterious	-6,51	high_impact	3,5	neutral	0,86	neutral	0,43	deleterious	3,91	23,5	0,03	0,35	NA	NA	disease	0,85	disease	0,67	disease	0,73	5	deleterious	0,99	neutral	0,04	deleterious	2	deleterious	0,83	low_impact	-2,18	medium_impact	-0,5	medium_impact	1,8	0,23	0,8	0,29	6,59	N	0,41	N	0,85	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4678	4678	T	G	MI.13197	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	209	70	L	R	cTt/cGt	-2,5	0	0	probably_damaging	0,93	neutral	0,07	neutral	3,62	deleterious	-7,9	deleterious	-5,63	high_impact	3,5	neutral	0,83	neutral	0,4	deleterious	3,97	23,6	0,01	0,35	NA	NA	disease	0,94	disease	0,7	disease	0,82	6	deleterious	0,98	neutral	0,07	deleterious	2	deleterious	0,89	low_impact	-1,83	medium_impact	-0,42	medium_impact	1,8	0,14	0,8	0,29	6,59	N	0,39	N	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4680	4680	C	A	MI.13198	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	211	71	L	M	Cta/Ata	-11,71	0	0	benign	0,07	neutral	0,2	neutral	3,57	deleterious	-3,95	neutral	1,99	neutral_impact	0,78	neutral	0,88	neutral	0,86	neutral	-1,01	0,02	0,1	0,4	NA	NA	neutral	0,25	neutral	0,41	neutral	0,16	7	neutral	0,78	deleterious	0,57	neutral	-6	neutral	0,26	medium_impact	0,23	medium_impact	-0,13	medium_impact	-0,49	0,48	0,8	0,58	7,58	N	0,42	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4680	4680	C	G	MI.13199	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	211	71	L	V	Cta/Gta	-11,71	0	0	benign	0,22	neutral	0,06	neutral	3,54	deleterious	-4,28	neutral	-1,26	medium_impact	2,42	neutral	0,92	neutral	0,61	neutral	1,45	13,03	0,08	0,35	NA	NA	disease	0,69	disease	0,61	disease	0,57	1	neutral	0,93	neutral	0,42	neutral	-3	deleterious	0,53	medium_impact	-0,29	medium_impact	-0,46	medium_impact	0,89	0,5	0,8	0,58	7,58	N	0,39	N	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8588	8588	T	C	MI.132	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	62	21	V	A	gTa/gCa	-2,42	0	0	benign	0,39	neutral	0,49	neutral	4,31	neutral	-0,84	neutral	-0,85	neutral_impact	-1,51	neutral	0,89	neutral	0,73	neutral	-0,21	1,05	0,35	0,65	neutral	0,44	neutral	0,06	neutral	0,26	neutral	0,25	5	neutral	0,44	deleterious	0,55	neutral	-6	neutral	0,38	medium_impact	-0,57	medium_impact	0,28	low_impact	-2,39	0,34	0,9	22,57	20,88	N	0,42	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9146	9146	C	G	MI.1320	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	620	207	A	G	gCc/gGc	7,3	1	0	probably_damaging	0,99	neutral	0,05	neutral	4,19	neutral	-1,21	deleterious	-3,57	medium_impact	2,77	neutral	0,66	neutral	0,59	deleterious	4,1	23,7	0,35	0,65	NA	NA	disease	0,89	disease	0,53	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,88	low_impact	-2,65	medium_impact	-0,43	medium_impact	1,28	0,82	0,9	48,67	8,68	P	0,5	N	0,86	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4681	4681	T	A	MI.13200	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	212	71	L	Q	cTa/cAa	-0,66	0	0	possibly_damaging	0,86	deleterious	0,04	neutral	3,46	deleterious	-7,75	deleterious	-2,56	medium_impact	3,46	neutral	0,83	neutral	0,51	deleterious	3,62	23,2	0,02	0,35	NA	NA	disease	0,87	disease	0,67	disease	0,72	4	neutral	0,98	neutral	0,09	deleterious	4	deleterious	0,81	low_impact	-1,52	medium_impact	-0,56	medium_impact	1,77	0,22	0,8	0,58	7,58	N	0,44	N	0,85	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4681	4681	T	C	MI.13201	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	212	71	L	P	cTa/cCa	-0,66	0	0	probably_damaging	0,92	deleterious	0,04	neutral	3,46	deleterious	-8,21	deleterious	-4,27	medium_impact	3,46	neutral	0,74	neutral	0,4	deleterious	3,61	23,2	0,02	0,35	NA	NA	disease	0,91	disease	0,76	disease	0,76	5	deleterious	0,99	neutral	0,06	deleterious	5	deleterious	0,89	low_impact	-1,77	medium_impact	-0,56	medium_impact	1,77	0,26	0,8	0,58	7,58	N	0,52	P	0,98	disease_causing_automatic	0	0,3	rs267606889	Pathogenic|Pathogenic	Leigh_syndrome_due_to_mitochondrial_complex_I_deficiency|Leigh_syndrome	RCV000010369.3|RCV000144022.2	MedGen|MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	T4681C	Leigh Syndrome	-	+	Reported	2
chrM	4681	4681	T	G	MI.13202	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	212	71	L	R	cTa/cGa	-0,66	0	0	possibly_damaging	0,86	deleterious	0,02	neutral	3,46	deleterious	-7,78	deleterious	-3,33	medium_impact	3,12	neutral	0,83	neutral	0,42	deleterious	3,74	23,3	0,02	0,35	NA	NA	disease	0,94	disease	0,77	disease	0,84	7	deleterious	0,99	neutral	0,08	deleterious	4	deleterious	0,88	low_impact	-1,52	medium_impact	-0,73	medium_impact	1,48	0,16	0,8	0,58	7,58	N	0,45	N	0,88	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4683	4683	A	T	MI.13203	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	214	72	M	L	Ata/Tta	-0,2	0	0	benign	0,01	neutral	0,75	neutral	4,88	neutral	1,19	neutral	-0,52	neutral_impact	-0,32	neutral	0,95	neutral	0,97	deleterious	0,47	7,22	0,21	0,45	NA	NA	disease	0,6	neutral	0,41	neutral	0,21	6	neutral	0,22	deleterious	0,87	neutral	-6	neutral	0,22	medium_impact	1,03	medium_impact	0,47	low_impact	-1,41	0,23	0,8	0,86	7,78	N	0,22	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4683	4683	A	C	MI.13204	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	214	72	M	L	Ata/Cta	-0,2	0	0	benign	0,01	neutral	0,75	neutral	4,88	neutral	1,19	neutral	-0,52	neutral_impact	-0,32	neutral	0,95	neutral	0,97	deleterious	0,37	6,34	0,21	0,45	NA	NA	disease	0,6	neutral	0,41	neutral	0,21	6	neutral	0,22	deleterious	0,87	neutral	-6	neutral	0,22	medium_impact	1,03	medium_impact	0,47	low_impact	-1,41	0,23	0,8	0,86	7,78	N	0,22	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4683	4683	A	G	MI.13205	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	214	72	M	V	Ata/Gta	-0,2	0	0	benign	0,34	neutral	0,29	neutral	4,75	neutral	0,5	neutral	-2,16	low_impact	1,19	neutral	0,92	neutral	0,75	neutral	1,51	13,38	0,19	0,45	NA	NA	disease	0,74	disease	0,59	disease	0,7	4	neutral	0,65	deleterious	0,48	neutral	-6	deleterious	0,55	medium_impact	-0,53	medium_impact	-0,01	medium_impact	-0,14	0,26	0,8	0,86	7,78	N	0,33	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4684	4684	T	C	MI.13206	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	215	72	M	T	aTa/aCa	-0,89	0	0	possibly_damaging	0,62	neutral	0,13	neutral	4,64	neutral	-0,92	deleterious	-3,81	low_impact	1,26	neutral	0,89	neutral	0,57	deleterious	2,83	21,5	0,1	0,4	NA	NA	disease	0,71	disease	0,59	disease	0,69	4	neutral	0,87	neutral	0,26	neutral	-3	deleterious	0,73	medium_impact	-0,99	medium_impact	-0,25	medium_impact	-0,08	0,18	0,8	0,86	7,78	N	0,43	N	0,74	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4684	4684	T	A	MI.13207	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	215	72	M	K	aTa/aAa	-0,89	0	0	possibly_damaging	0,79	neutral	0,12	neutral	4,6	neutral	-2,71	deleterious	-4,44	medium_impact	2,5	neutral	0,83	neutral	0,41	deleterious	4,09	23,7	0,03	0,35	NA	NA	disease	0,89	disease	0,67	disease	0,79	6	neutral	0,92	neutral	0,17	NA	0	deleterious	0,8	low_impact	-1,32	medium_impact	-0,27	medium_impact	0,96	0,18	0,8	0,86	7,78	N	0,35	N	0,87	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4685	4685	A	C	MI.13208	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	216	72	M	I	atA/atC	5,55	0,87	0	benign	0,34	neutral	0,36	neutral	4,73	neutral	0,14	neutral	-1,78	low_impact	0,88	neutral	0,84	neutral	0,37	deleterious	3,18	22,7	0,2	0,45	NA	NA	disease	0,82	disease	0,59	disease	0,74	5	neutral	0,57	deleterious	0,51	neutral	-6	deleterious	0,6	medium_impact	-0,53	medium_impact	0,07	medium_impact	-0,4	0,28	0,8	0,86	7,78	N	0,41	N	0,57	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4685	4685	A	T	MI.13209	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	216	72	M	I	atA/atT	5,55	0,87	0	benign	0,34	neutral	0,36	neutral	4,73	neutral	0,14	neutral	-1,78	low_impact	0,88	neutral	0,84	neutral	0,37	deleterious	3,35	22,9	0,2	0,45	NA	NA	disease	0,82	disease	0,59	disease	0,74	5	neutral	0,57	deleterious	0,51	neutral	-6	deleterious	0,6	medium_impact	-0,53	medium_impact	0,07	medium_impact	-0,4	0,28	0,8	0,86	7,78	N	0,41	N	0,57	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9146	9146	C	T	MI.1321	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	620	207	A	V	gCc/gTc	7,3	1	0	probably_damaging	1	neutral	0,05	neutral	4,1	neutral	-2,29	deleterious	-3,58	high_impact	3,77	damaging	0,45	neutral	0,44	deleterious	4,64	24,5	0,41	0,65	NA	NA	disease	0,91	disease	0,65	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,43	high_impact	2,13	0,83	0,9	48,67	8,68	P	0,66	P	0,75	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4686	4686	G	T	MI.13210	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	217	73	A	S	Gct/Tct	-2,04	0	0	possibly_damaging	0,87	neutral	0,53	neutral	4,51	neutral	-1,58	neutral	-2,31	neutral_impact	0,7	neutral	0,82	neutral	0,87	deleterious	2,07	16,69	0,22	0,45	NA	NA	neutral	0,27	neutral	0,29	neutral	0,19	6	neutral	0,85	neutral	0,33	neutral	-3	deleterious	0,7	low_impact	-1,55	medium_impact	0,24	medium_impact	-0,56	0,55	0,8	0,58	7,45	N	0,33	N	0,29	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4686	4686	G	A	MI.13211	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	217	73	A	T	Gct/Act	-2,04	0	0	benign	0,36	neutral	0,41	neutral	4,45	neutral	-2,96	deleterious	-3,14	medium_impact	2,21	neutral	0,89	neutral	0,46	deleterious	2,97	22,1	0,11	0,4	NA	NA	disease	0,83	neutral	0,41	neutral	0,49	0	neutral	0,52	deleterious	0,53	neutral	-3	deleterious	0,62	medium_impact	-0,57	medium_impact	0,12	medium_impact	0,72	0,72	0,85	0,58	7,45	N	0,36	N	0,42	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4686	4686	G	C	MI.13212	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	217	73	A	P	Gct/Cct	-2,04	0	0	probably_damaging	0,99	neutral	0,22	neutral	4,4	deleterious	-4,33	deleterious	-4,24	medium_impact	3,17	neutral	0,76	damaging	0,09	deleterious	3,65	23,2	0,03	0,35	NA	NA	disease	0,96	disease	0,73	disease	0,83	7	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,91	low_impact	-2,62	medium_impact	-0,1	medium_impact	1,52	0,52	0,8	0,58	7,45	N	0,29	N	0,87	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4687	4687	C	A	MI.13213	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	218	73	A	D	gCt/gAt	0,03	0	0	probably_damaging	0,98	neutral	0,2	neutral	4,41	deleterious	-3,95	deleterious	-4,93	high_impact	3,52	neutral	0,83	damaging	0,09	deleterious	4,42	24,2	0,02	0,35	NA	NA	disease	0,95	disease	0,72	disease	0,83	6	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-2,34	medium_impact	-0,13	medium_impact	1,82	0,28	0,8	0,58	7,45	N	0,32	N	0,88	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4687	4687	C	G	MI.13214	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	218	73	A	G	gCt/gGt	0,03	0	0	probably_damaging	0,93	neutral	0,44	neutral	4,66	neutral	0,55	deleterious	-2,73	low_impact	1,14	neutral	0,9	neutral	0,83	deleterious	2,52	19,6	0,23	0,45	NA	NA	disease	0,8	neutral	0,38	neutral	0,19	6	neutral	0,93	neutral	0,26	neutral	-2	deleterious	0,79	low_impact	-1,83	medium_impact	0,15	medium_impact	-0,19	0,68	0,85	0,58	7,45	N	0,3	N	0,38	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4687	4687	C	T	MI.13215	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	218	73	A	V	gCt/gTt	0,03	0	0	possibly_damaging	0,87	neutral	0,53	neutral	4,5	neutral	-2,79	deleterious	-3,49	medium_impact	2,72	neutral	0,88	damaging	0,26	deleterious	4,21	23,9	0,08	0,35	NA	NA	disease	0,89	disease	0,61	disease	0,73	5	neutral	0,85	neutral	0,33	NA	0	deleterious	0,82	low_impact	-1,55	medium_impact	0,24	medium_impact	1,15	0,7	0,85	0,58	7,45	N	0,35	N	0,46	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4689	4689	A	G	MI.13216	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	220	74	I	V	Atc/Gtc	-14,94	0	0	probably_damaging	0,99	neutral	0,51	neutral	4,47	neutral	-1,41	neutral	-0,36	neutral_impact	0,55	neutral	0,91	neutral	0,93	neutral	1,48	13,22	0,49	0,55	NA	NA	neutral	0,33	neutral	0,29	neutral	0,16	7	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,7	low_impact	-2,62	medium_impact	0,22	medium_impact	-0,68	0,4	0,8	0,86	8,3	N	0,39	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4689	4689	A	C	MI.13217	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	220	74	I	L	Atc/Ctc	-14,94	0	0	probably_damaging	0,99	neutral	0,66	neutral	4,48	neutral	-0,57	neutral	-1,56	low_impact	1,45	neutral	0,91	neutral	0,54	deleterious	3,63	23,2	0,28	0,45	NA	NA	disease	0,61	neutral	0,41	neutral	0,46	1	deleterious	0,99	neutral	0,34	neutral	-2	deleterious	0,74	low_impact	-2,62	medium_impact	0,37	medium_impact	0,08	0,46	0,8	0,86	8,3	N	0,28	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4689	4689	A	T	MI.13218	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	220	74	I	F	Atc/Ttc	-14,94	0	0	probably_damaging	1	neutral	0,71	neutral	4,42	neutral	-2,31	deleterious	-3,33	low_impact	1,59	neutral	0,9	damaging	0,18	deleterious	3,75	23,3	0,19	0,45	NA	NA	disease	0,75	neutral	0,5	disease	0,5	0	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,79	low_impact	-3,54	medium_impact	0,42	medium_impact	0,19	0,51	0,8	0,86	8,3	N	0,25	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4690	4690	T	A	MI.13219	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	221	74	I	N	aTc/aAc	-0,43	0	0	probably_damaging	1	neutral	0,31	neutral	4,32	deleterious	-4,75	deleterious	-5,49	medium_impact	2,29	neutral	0,82	damaging	0,13	deleterious	4,27	23,9	0,08	0,35	NA	NA	disease	0,79	neutral	0,49	disease	0,59	2	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,02	medium_impact	0,78	0,32	0,8	0,86	8,3	N	0,26	N	0,98	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9146	9146	C	A	MI.1322	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	620	207	A	D	gCc/gAc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	4,05	deleterious	-4,01	deleterious	-5,34	high_impact	4,32	damaging	0,55	neutral	0,49	deleterious	4,68	24,5	0,15	0,65	NA	NA	disease	0,96	disease	0,73	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,93	low_impact	-3,6	low_impact	-1,4	high_impact	2,6	0,67	0,9	48,67	8,68	N	0,5	N	0,99	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4690	4690	T	G	MI.13220	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	221	74	I	S	aTc/aGc	-0,43	0	0	probably_damaging	1	neutral	0,43	neutral	4,36	deleterious	-3,09	deleterious	-4,26	neutral_impact	0,01	neutral	0,8	neutral	0,34	deleterious	2,89	21,8	0,05	0,35	NA	NA	neutral	0,24	neutral	0,3	neutral	0,17	7	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,14	low_impact	-1,14	0,33	0,8	0,86	8,3	N	0,27	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4690	4690	T	C	MI.13221	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	221	74	I	T	aTc/aCc	-0,43	0	0	probably_damaging	1	neutral	0,4	neutral	4,35	neutral	-2,96	deleterious	-3,3	low_impact	1,04	neutral	0,88	neutral	0,66	deleterious	2,17	17,32	0,1	0,4	NA	NA	neutral	0,48	neutral	0,29	neutral	0,19	6	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	0,11	medium_impact	-0,27	0,32	0,8	0,86	8,3	N	0,34	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4691	4691	C	A	MI.13222	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	222	74	I	M	atC/atA	0,03	0	0	probably_damaging	1	neutral	0,22	neutral	4,43	neutral	-2,12	neutral	-2,23	low_impact	1,31	neutral	0,85	damaging	0,13	deleterious	3,74	23,3	0,32	0,5	NA	NA	disease	0,58	neutral	0,37	neutral	0,45	1	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	-0,1	medium_impact	-0,04	0,5	0,8	0,86	8,3	N	0,3	N	0,65	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4691	4691	C	G	MI.13223	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	222	74	I	M	atC/atG	0,03	0	0	probably_damaging	1	neutral	0,22	neutral	4,43	neutral	-2,12	neutral	-2,23	low_impact	1,31	neutral	0,85	damaging	0,13	deleterious	3,27	22,8	0,32	0,5	NA	NA	disease	0,58	neutral	0,37	neutral	0,45	1	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	-0,1	medium_impact	-0,04	0,5	0,8	0,86	8,3	N	0,3	N	0,65	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4692	4692	C	A	MI.13224	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	223	75	L	I	Ctc/Atc	-7,34	0	0	benign	0,01	neutral	1	neutral	4,53	neutral	-0,71	neutral	0,79	neutral_impact	-0,69	neutral	0,92	neutral	0,92	neutral	1,23	11,89	0,36	0,5	NA	NA	neutral	0,33	neutral	0,19	neutral	0,15	7	neutral	0,01	deleterious	1	neutral	-6	neutral	0,12	medium_impact	1,03	high_impact	1,87	low_impact	-1,73	0,52	0,8	2,59	7,65	N	0,27	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4692	4692	C	T	MI.13225	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	223	75	L	F	Ctc/Ttc	-7,34	0	0	benign	0,01	neutral	0,5	neutral	4,45	neutral	-1,46	neutral	-1,86	low_impact	0,98	neutral	0,88	neutral	0,82	deleterious	3,83	23,4	0,24	0,45	NA	NA	disease	0,64	neutral	0,44	neutral	0,43	1	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,17	medium_impact	1,03	medium_impact	0,21	medium_impact	-0,32	0,48	0,8	2,59	7,65	N	0,28	N	0,19	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4692	4692	C	G	MI.13226	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	223	75	L	V	Ctc/Gtc	-7,34	0	0	benign	0,02	neutral	0,45	neutral	4,45	neutral	-1,42	neutral	0,49	neutral_impact	0,44	neutral	0,92	neutral	0,97	deleterious	1,96	15,99	0,37	0,5	NA	NA	neutral	0,47	neutral	0,25	neutral	0,19	6	neutral	0,53	deleterious	0,72	neutral	-6	neutral	0,14	medium_impact	0,75	medium_impact	0,16	medium_impact	-0,77	0,64	0,8	2,59	7,65	N	0,39	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4693	4693	T	G	MI.13227	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	224	75	L	R	cTc/cGc	-0,43	0	0	possibly_damaging	0,56	neutral	0,2	neutral	4,35	deleterious	-3,86	deleterious	-3,72	medium_impact	2,33	neutral	0,84	neutral	0,47	deleterious	4,07	23,7	0,02	0,35	NA	NA	disease	0,9	disease	0,66	disease	0,78	6	neutral	0,79	neutral	0,32	NA	0	deleterious	0,77	medium_impact	-0,89	medium_impact	-0,13	medium_impact	0,82	0,21	0,8	2,59	7,65	N	0,33	N	0,71	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4693	4693	T	A	MI.13228	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	224	75	L	H	cTc/cAc	-0,43	0	0	possibly_damaging	0,74	neutral	0,28	neutral	4,35	deleterious	-4,42	deleterious	-4	medium_impact	2,33	neutral	0,85	neutral	0,51	deleterious	3,98	23,6	0,04	0,35	NA	NA	disease	0,7	disease	0,63	disease	0,71	4	neutral	0,81	neutral	0,27	NA	0	deleterious	0,66	low_impact	-1,21	medium_impact	-0,02	medium_impact	0,82	0,22	0,8	2,59	7,65	N	0,32	N	0,7	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4693	4693	T	C	MI.13229	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	224	75	L	P	cTc/cCc	-0,43	0	0	possibly_damaging	0,74	neutral	0,11	neutral	4,34	deleterious	-4,47	deleterious	-3,83	low_impact	1,78	neutral	0,73	neutral	0,41	deleterious	3,75	23,3	0,02	0,35	NA	NA	disease	0,9	disease	0,61	disease	0,76	5	neutral	0,92	neutral	0,19	neutral	-3	deleterious	0,77	low_impact	-1,21	medium_impact	-0,3	medium_impact	0,35	0,25	0,8	2,59	7,65	N	0,32	N	0,84	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9148	9148	T	A	MI.1323	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	622	208	L	M	Tta/Ata	-9,13	0	0,01	probably_damaging	1	neutral	1	neutral	4,36	neutral	-0,94	neutral	0,11	neutral_impact	-0,18	neutral	0,84	neutral	0,85	neutral	1	10,67	0,3	0,65	NA	NA	neutral	0,05	neutral	0,23	neutral	0,17	7	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,71	low_impact	-3,6	high_impact	1,98	low_impact	-1,25	0,73	0,9	NA	NA	N	0,3	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4695	4695	T	A	MI.13230	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	226	76	F	I	Ttc/Atc	-9,41	0	0	benign	0	neutral	1	neutral	4,78	neutral	-1,31	neutral	2,75	neutral_impact	-1,75	neutral	0,89	neutral	0,93	neutral	-0,41	0,38	0,23	0,45	disease	0,55	neutral	0,32	neutral	0,22	disease	0,6	2	neutral	0	deleterious	1	neutral	-6	neutral	0,15	medium_impact	1,95	high_impact	1,87	low_impact	-2,62	0,47	0,8	2,59	8,22	N	0,27	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4695	4695	T	C	MI.13231	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	226	76	F	L	Ttc/Ctc	-9,41	0	0	benign	0	neutral	0,84	neutral	4,83	neutral	0,23	neutral	1,93	neutral_impact	-0,78	neutral	0,96	neutral	0,97	deleterious	0,23	5	0,26	0,45	neutral	0,35	neutral	0,49	neutral	0,31	neutral	0,28	5	neutral	0,16	deleterious	0,92	neutral	-6	neutral	0,13	medium_impact	1,95	medium_impact	0,61	low_impact	-1,8	0,67	0,85	2,59	8,22	N	0,22	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4695	4695	T	G	MI.13232	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	226	76	F	V	Ttc/Gtc	-9,41	0	0	benign	0	neutral	0,45	neutral	4,77	neutral	-1,18	neutral	2,01	neutral_impact	0,02	neutral	0,91	neutral	0,82	deleterious	0,86	9,86	0,15	0,4	disease	0,63	disease	0,61	neutral	0,33	neutral	0,27	5	neutral	0,55	deleterious	0,73	neutral	-6	neutral	0,19	medium_impact	1,95	medium_impact	0,16	low_impact	-1,13	0,4	0,8	2,59	8,22	N	0,3	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4696	4696	T	C	MI.13233	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	227	76	F	S	tTc/tCc	-0,89	0	0	benign	0	neutral	0,59	neutral	4,66	neutral	-2,73	neutral	-1,82	neutral_impact	-0,15	neutral	0,93	neutral	0,92	deleterious	0,88	9,95	0,07	0,35	disease	0,68	disease	0,53	neutral	0,36	neutral	0,28	4	neutral	0,41	deleterious	0,8	neutral	-6	neutral	0,19	medium_impact	1,95	medium_impact	0,3	low_impact	-1,27	0,27	0,8	2,59	8,22	N	0,27	N	0	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4696	4696	T	A	MI.13234	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	227	76	F	Y	tTc/tAc	-0,89	0	0	benign	0	neutral	0,43	neutral	4,75	neutral	-0,17	neutral	-0,86	neutral_impact	0,12	neutral	0,98	neutral	0,9	deleterious	0,69	8,77	0,24	0,45	neutral	0,31	neutral	0,49	neutral	0,31	neutral	0,34	3	neutral	0,57	deleterious	0,72	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,14	low_impact	-1,04	0,62	0,8	2,59	8,22	N	0,37	N	0,03	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4696	4696	T	G	MI.13235	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	227	76	F	C	tTc/tGc	-0,89	0	0	benign	0	neutral	0,12	neutral	4,62	deleterious	-4	neutral	-1,1	low_impact	1,15	neutral	0,92	neutral	0,58	deleterious	1,99	16,17	0,07	0,35	disease	0,89	disease	0,76	disease	0,54	disease	0,68	4	neutral	0,88	deleterious	0,56	neutral	-6	neutral	0,24	medium_impact	1,95	medium_impact	-0,27	medium_impact	-0,18	0,2	0,8	2,59	8,22	N	0,36	N	0,12	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4697	4697	C	A	MI.13236	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	228	76	F	L	ttC/ttA	-0,66	0	0	benign	0	neutral	0,84	neutral	4,83	neutral	0,23	neutral	1,93	neutral_impact	-0,78	neutral	0,96	neutral	0,97	neutral	0,89	10,02	0,26	0,45	neutral	0,35	neutral	0,49	neutral	0,31	neutral	0,28	5	neutral	0,16	deleterious	0,92	neutral	-6	neutral	0,13	medium_impact	1,95	medium_impact	0,61	low_impact	-1,8	0,67	0,85	2,59	8,22	N	0,21	N	0,06	polymorphism	1	0,01	rs386828948	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4697	4697	C	G	MI.13237	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	228	76	F	L	ttC/ttG	-0,66	0	0	benign	0	neutral	0,84	neutral	4,83	neutral	0,23	neutral	1,93	neutral_impact	-0,78	neutral	0,96	neutral	0,97	deleterious	0,58	7,99	0,26	0,45	neutral	0,35	neutral	0,49	neutral	0,31	neutral	0,28	5	neutral	0,16	deleterious	0,92	neutral	-6	neutral	0,13	medium_impact	1,95	medium_impact	0,61	low_impact	-1,8	0,67	0,85	2,59	8,22	N	0,22	N	0,06	polymorphism	1	0,01	rs386828948	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4698	4698	A	C	MI.13238	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	229	77	N	H	Aac/Cac	-5,73	0	0	probably_damaging	1	neutral	0,54	neutral	4,62	neutral	-1,25	deleterious	-4,81	high_impact	3,52	neutral	0,83	neutral	0,3	deleterious	2,93	22	0,31	0,45	disease	0,81	disease	0,87	disease	0,77	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0,25	medium_impact	1,82	0,24	0,8	0,58	8,65	N	0,29	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4698	4698	A	T	MI.13239	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	229	77	N	Y	Aac/Tac	-5,73	0	0	probably_damaging	1	neutral	1	neutral	4,67	neutral	0,65	deleterious	-7,44	medium_impact	2,55	neutral	0,8	neutral	0,34	deleterious	3,56	23,1	0,07	0,35	disease	0,87	disease	0,9	disease	0,71	disease	0,66	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,84	low_impact	-3,54	high_impact	1,87	medium_impact	1	0,23	0,8	0,58	8,65	N	0,19	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9148	9148	T	G	MI.1324	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	622	208	L	V	Tta/Gta	-9,13	0	0,01	probably_damaging	0,99	neutral	0,53	neutral	4,37	neutral	0,14	neutral	-1,84	neutral_impact	0,76	neutral	0,86	neutral	0,78	deleterious	3,44	23	0,31	0,65	NA	NA	neutral	0,44	neutral	0,31	neutral	0,21	6	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,79	low_impact	-2,65	medium_impact	0,32	medium_impact	-0,45	0,5	0,9	NA	NA	N	0,29	N	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4698	4698	A	G	MI.13240	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	229	77	N	D	Aac/Gac	-5,73	0	0	probably_damaging	1	neutral	0,21	neutral	4,62	neutral	-1,83	deleterious	-4,81	medium_impact	3,32	neutral	0,86	neutral	0,52	deleterious	3,65	23,2	0,36	0,5	disease	0,65	disease	0,83	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,11	medium_impact	1,65	0,34	0,8	0,58	8,65	N	0,32	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4699	4699	A	C	MI.13241	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	230	77	N	T	aAc/aCc	6,71	1	0	probably_damaging	1	neutral	0,39	neutral	4,68	neutral	1,02	deleterious	-5,73	medium_impact	2,67	neutral	0,89	neutral	0,48	deleterious	3,19	22,7	0,21	0,45	disease	0,59	disease	0,87	disease	0,56	disease	0,66	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,1	medium_impact	1,1	0,37	0,8	0,58	8,65	P	0,58	P	0,69	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4699	4699	A	T	MI.13242	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	230	77	N	I	aAc/aTc	6,71	1	0	probably_damaging	1	neutral	0,4	neutral	4,9	neutral	3,08	deleterious	-8,06	medium_impact	2,83	neutral	0,83	neutral	0,55	deleterious	3,87	23,5	0,11	0,4	disease	0,84	disease	0,95	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0,11	medium_impact	1,24	0,19	0,8	0,58	8,65	P	0,58	P	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4699	4699	A	G	MI.13243	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	230	77	N	S	aAc/aGc	6,71	1	0	probably_damaging	1	neutral	0,41	neutral	4,67	neutral	0,77	deleterious	-4,79	medium_impact	2,1	neutral	0,83	neutral	0,6	deleterious	2,93	22	0,37	0,5	disease	0,52	disease	0,82	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0,12	medium_impact	0,62	0,44	0,8	0,58	8,65	P	0,56	P	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4700	4700	C	G	MI.13244	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	231	77	N	K	aaC/aaG	4,4	1	0	probably_damaging	1	neutral	0,29	neutral	4,63	neutral	-0,65	deleterious	-5,74	medium_impact	3,06	neutral	0,78	neutral	0,35	deleterious	3,79	23,4	0,24	0,45	disease	0,54	disease	0,91	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,43	0,58	0,8	0,58	8,65	N	0,52	P	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4700	4700	C	A	MI.13245	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	231	77	N	K	aaC/aaA	4,4	1	0	probably_damaging	1	neutral	0,29	neutral	4,63	neutral	-0,65	deleterious	-5,74	medium_impact	3,06	neutral	0,78	neutral	0,35	deleterious	4,27	23,9	0,24	0,45	disease	0,54	disease	0,91	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,43	0,58	0,8	0,58	8,65	N	0,52	P	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4701	4701	A	C	MI.13246	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	232	78	N	H	Aat/Cat	-2,96	0	0	possibly_damaging	0,52	neutral	0,54	neutral	4,66	neutral	0,72	neutral	-0,24	low_impact	1,28	neutral	0,88	neutral	0,75	neutral	1,64	14,09	0,35	0,5	disease	0,57	disease	0,52	neutral	0,43	neutral	0,42	2	neutral	0,49	deleterious	0,51	neutral	-3	deleterious	0,69	medium_impact	-0,83	medium_impact	0,25	medium_impact	-0,07	0,29	0,8	15,27	10,16	N	0,29	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4701	4701	A	T	MI.13247	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	232	78	N	Y	Aat/Tat	-2,96	0	0	benign	0,02	neutral	1	neutral	5,01	neutral	4,51	neutral	1,32	neutral_impact	-0,38	neutral	0,92	neutral	0,89	deleterious	1,85	15,27	0,11	0,4	neutral	0,39	disease	0,65	neutral	0,25	neutral	0,36	3	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,25	medium_impact	0,75	high_impact	1,87	low_impact	-1,46	0,21	0,8	15,27	10,16	N	0,23	N	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4701	4701	A	G	MI.13248	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	232	78	N	D	Aat/Gat	-2,96	0	0	benign	0,13	neutral	0,23	neutral	4,64	neutral	-0,87	neutral	-1,16	low_impact	0,94	neutral	0,85	neutral	0,49	deleterious	3,46	23	0,52	0,6	neutral	0,38	disease	0,59	disease	0,53	disease	0,57	1	neutral	0,74	deleterious	0,55	neutral	-6	deleterious	0,62	medium_impact	-0,04	medium_impact	-0,08	medium_impact	-0,35	0,41	0,8	15,27	10,16	N	0,34	N	0,34	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4702	4702	A	T	MI.13249	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	233	78	N	I	aAt/aTt	-0,2	0	0	benign	0,37	neutral	0,41	neutral	4,73	neutral	2,5	neutral	2,61	neutral_impact	-0,1	neutral	0,9	neutral	0,65	deleterious	2,76	21,2	0,11	0,4	neutral	0,37	disease	0,79	neutral	0,35	disease	0,58	1	neutral	0,52	deleterious	0,52	neutral	-6	deleterious	0,67	medium_impact	-0,59	medium_impact	0,12	low_impact	-1,23	0,15	0,8	15,27	10,16	N	0,28	N	0,27	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9149	9149	T	C	MI.1325	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	623	208	L	S	tTa/tCa	-1,95	0	0	probably_damaging	1	neutral	0,14	neutral	4,34	neutral	-1,5	deleterious	-4,11	medium_impact	2,42	neutral	0,76	neutral	0,53	deleterious	3,86	23,5	0,21	0,65	NA	NA	disease	0,7	disease	0,57	disease	0,71	4	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	-0,15	medium_impact	0,98	0,62	0,9	NA	NA	N	0,31	N	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4702	4702	A	G	MI.13250	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	233	78	N	S	aAt/aGt	-0,2	0	0	benign	0	neutral	0,44	neutral	4,69	neutral	1,72	neutral	0,44	neutral_impact	-0,4	neutral	0,93	neutral	0,93	deleterious	1,84	15,25	0,45	0,55	neutral	0,33	neutral	0,45	neutral	0,21	neutral	0,45	1	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,21	medium_impact	1,95	medium_impact	0,15	low_impact	-1,48	0,33	0,8	15,27	10,16	N	0,4	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4702	4702	A	C	MI.13251	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	233	78	N	T	aAt/aCt	-0,2	0	0	benign	0,01	neutral	0,41	neutral	4,68	neutral	1,56	neutral	0,94	neutral_impact	-0,04	neutral	0,91	neutral	0,9	deleterious	2,1	16,87	0,27	0,45	neutral	0,29	neutral	0,47	neutral	0,18	neutral	0,44	1	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,21	medium_impact	1,03	medium_impact	0,12	low_impact	-1,18	0,33	0,8	15,27	10,16	N	0,47	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4703	4703	T	A	MI.13252	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	234	78	N	K	aaT/aaA	0,72	0	0,01	benign	0,13	neutral	0,33	neutral	4,65	neutral	0,3	neutral	-0,04	neutral_impact	0,59	neutral	0,85	neutral	0,53	deleterious	4,08	23,7	0,31	0,45	neutral	0,35	disease	0,7	disease	0,57	disease	0,65	3	neutral	0,62	deleterious	0,6	neutral	-6	deleterious	0,64	medium_impact	-0,04	medium_impact	0,04	medium_impact	-0,65	0,41	0,8	15,27	10,16	N	0,29	N	0,33	polymorphism	1	0,01	rs386828949	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4703	4703	T	G	MI.13253	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	234	78	N	K	aaT/aaG	0,72	0	0,01	benign	0,13	neutral	0,33	neutral	4,65	neutral	0,3	neutral	-0,04	neutral_impact	0,59	neutral	0,85	neutral	0,53	deleterious	3,76	23,3	0,31	0,45	neutral	0,35	disease	0,7	disease	0,57	disease	0,65	3	neutral	0,62	deleterious	0,6	neutral	-6	deleterious	0,64	medium_impact	-0,04	medium_impact	0,04	medium_impact	-0,65	0,41	0,8	15,27	10,16	N	0,3	N	0,33	polymorphism	1	0,01	rs386828949	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4704	4704	A	C	MI.13254	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	235	79	M	L	Ata/Cta	-8,26	0	0,01	benign	0	neutral	0,93	neutral	4,73	neutral	1,34	neutral	-0,41	neutral_impact	0,09	neutral	0,96	neutral	0,97	neutral	-1,63	0	0,35	0,5	neutral	0,33	disease	0,56	neutral	0,35	neutral	0,2	6	neutral	0,06	deleterious	0,97	neutral	-6	neutral	0,19	medium_impact	1,95	medium_impact	0,83	low_impact	-1,07	0,38	0,8	11,82	8,87	N	0,29	N	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4704	4704	A	T	MI.13255	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	235	79	M	L	Ata/Tta	-8,26	0	0,01	benign	0	neutral	0,93	neutral	4,73	neutral	1,34	neutral	-0,41	neutral_impact	0,09	neutral	0,96	neutral	0,97	neutral	-1,56	0	0,35	0,5	neutral	0,33	disease	0,56	neutral	0,35	neutral	0,2	6	neutral	0,06	deleterious	0,97	neutral	-6	neutral	0,19	medium_impact	1,95	medium_impact	0,83	low_impact	-1,07	0,38	0,8	11,82	8,87	N	0,29	N	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4704	4704	A	G	MI.13256	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	235	79	M	V	Ata/Gta	-8,26	0	0,01	benign	0,01	neutral	0,5	neutral	4,72	neutral	1,3	neutral	-2,04	low_impact	1,4	neutral	0,91	neutral	0,76	neutral	-0,7	0,07	0,29	0,45	neutral	0,48	disease	0,67	disease	0,63	disease	0,64	3	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,22	medium_impact	1,03	medium_impact	0,21	medium_impact	0,03	0,41	0,8	11,82	8,87	N	0,22	N	0,36	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4705	4705	T	A	MI.13257	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	236	79	M	K	aTa/aAa	-0,43	0	0,02	benign	0,41	neutral	0,34	neutral	4,63	neutral	-0,46	deleterious	-4,52	low_impact	1,61	neutral	0,91	neutral	0,84	deleterious	0,54	7,7	0,04	0,35	neutral	0,33	disease	0,86	disease	0,71	disease	0,65	3	neutral	0,61	neutral	0,47	neutral	-6	deleterious	0,61	medium_impact	-0,65	medium_impact	0,05	medium_impact	0,21	0,17	0,8	11,82	8,87	N	0,39	N	0,42	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4705	4705	T	C	MI.13258	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	236	79	M	T	aTa/aCa	-0,43	0	0,02	benign	0,18	neutral	0,43	neutral	4,66	neutral	0,39	deleterious	-3,88	low_impact	1,26	neutral	0,92	neutral	0,91	neutral	-0,41	0,36	0,11	0,4	neutral	0,42	disease	0,7	disease	0,62	disease	0,63	3	neutral	0,48	deleterious	0,63	neutral	-6	neutral	0,42	medium_impact	-0,19	medium_impact	0,14	medium_impact	-0,08	0,16	0,8	11,82	8,87	N	0,34	N	0,17	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4706	4706	A	T	MI.13259	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	237	79	M	I	atA/atT	0,72	0	0,01	benign	0,06	neutral	0,55	neutral	4,66	neutral	0,4	neutral	-1,6	neutral_impact	0,74	neutral	0,91	neutral	0,89	deleterious	0,11	3,72	0,26	0,45	disease	0,63	disease	0,76	neutral	0,37	neutral	0,41	2	neutral	0,39	deleterious	0,75	neutral	-6	neutral	0,34	medium_impact	0,3	medium_impact	0,26	medium_impact	-0,52	0,38	0,8	11,82	8,87	N	0,25	N	0,34	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9149	9149	T	G	MI.1326	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	623	208	L	W	tTa/tGa	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	4,26	deleterious	-4,2	deleterious	-4,18	medium_impact	3,23	neutral	0,76	neutral	0,44	deleterious	3,85	23,4	0,13	0,65	NA	NA	disease	0,83	disease	0,59	disease	0,77	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	medium_impact	1,67	0,5	0,9	NA	NA	N	0,34	N	0,87	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4706	4706	A	C	MI.13260	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	237	79	M	I	atA/atC	0,72	0	0,01	benign	0,06	neutral	0,55	neutral	4,66	neutral	0,4	neutral	-1,6	neutral_impact	0,74	neutral	0,91	neutral	0,89	deleterious	0,06	3,24	0,26	0,45	disease	0,63	disease	0,76	neutral	0,37	neutral	0,41	2	neutral	0,39	deleterious	0,75	neutral	-6	neutral	0,34	medium_impact	0,3	medium_impact	0,26	medium_impact	-0,52	0,38	0,8	11,82	8,87	N	0,25	N	0,34	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4707	4707	C	T	MI.13261	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	238	80	L	F	Ctc/Ttc	-0,43	0	0	benign	0,01	neutral	0,91	neutral	4,52	neutral	-1,14	neutral	2,32	neutral_impact	0,44	neutral	0,95	neutral	0,91	deleterious	0,24	5,11	0,23	0,45	disease	0,54	neutral	0,38	neutral	0,24	neutral	0,44	1	neutral	0,06	deleterious	0,95	neutral	-6	neutral	0,17	medium_impact	1,03	medium_impact	0,77	medium_impact	-0,77	0,6	0,8	12,39	10,1	N	0,23	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4707	4707	C	G	MI.13262	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	238	80	L	V	Ctc/Gtc	-0,43	0	0	benign	0,01	neutral	0,54	neutral	4,5	neutral	-1,42	neutral	-0,34	low_impact	1,57	neutral	0,89	neutral	0,7	deleterious	0,33	6,01	0,29	0,45	neutral	0,49	neutral	0,35	neutral	0,4	neutral	0,4	2	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,16	medium_impact	1,03	medium_impact	0,25	medium_impact	0,18	0,55	0,8	12,39	10,1	N	0,34	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4707	4707	C	A	MI.13263	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	238	80	L	I	Ctc/Atc	-0,43	0	0	benign	0,02	neutral	0,62	neutral	4,59	neutral	-0,37	neutral	-0,17	low_impact	1	neutral	0,89	neutral	0,74	neutral	0,95	10,38	0,32	0,5	neutral	0,5	neutral	0,44	neutral	0,23	neutral	0,26	5	neutral	0,35	deleterious	0,8	neutral	-6	neutral	0,18	medium_impact	0,75	medium_impact	0,33	medium_impact	-0,3	0,61	0,8	12,39	10,1	N	0,35	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4708	4708	T	G	MI.13264	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	239	80	L	R	cTc/cGc	-5,96	0	0	possibly_damaging	0,58	neutral	0,33	neutral	4,43	deleterious	-3,05	neutral	-0,58	medium_impact	2,66	neutral	0,83	neutral	0,44	deleterious	2,83	21,5	0,03	0,35	disease	0,75	disease	0,84	disease	0,59	disease	0,73	5	neutral	0,68	neutral	0,38	NA	0	deleterious	0,72	medium_impact	-0,93	medium_impact	0,04	medium_impact	1,1	0,06	0,8	12,39	10,1	N	0,31	N	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4708	4708	T	C	MI.13265	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	239	80	L	P	cTc/cCc	-5,96	0	0	possibly_damaging	0,66	neutral	0,19	neutral	4,42	deleterious	-3,91	neutral	-1,62	low_impact	1,86	neutral	0,74	neutral	0,36	deleterious	2,69	20,8	0,03	0,35	disease	0,82	disease	0,84	disease	0,62	disease	0,73	5	neutral	0,83	neutral	0,27	neutral	-3	deleterious	0,77	low_impact	-1,06	medium_impact	-0,14	medium_impact	0,42	0,1	0,8	12,39	10,1	N	0,26	N	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4708	4708	T	A	MI.13266	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	239	80	L	H	cTc/cAc	-5,96	0	0	possibly_damaging	0,67	neutral	0,54	neutral	4,43	neutral	-2,97	neutral	2,13	neutral_impact	0,72	neutral	0,81	neutral	0,96	deleterious	2,52	19,57	0,06	0,35	disease	0,72	neutral	0,36	neutral	0,33	disease	0,63	3	neutral	0,63	neutral	0,44	neutral	-3	deleterious	0,63	low_impact	-1,08	medium_impact	0,25	medium_impact	-0,54	0,12	0,8	12,39	10,1	N	0,31	N	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4710	4710	T	A	MI.13267	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	241	81	S	T	Tcc/Acc	-9,41	0	0	benign	0,17	neutral	0,52	neutral	4,76	neutral	0,74	neutral	-1,98	neutral_impact	-0,33	neutral	0,88	neutral	0,95	neutral	1,49	13,25	0,31	0,5	disease	0,54	neutral	0,12	neutral	0,21	neutral	0,34	3	neutral	0,38	deleterious	0,68	neutral	-6	deleterious	0,61	medium_impact	-0,17	medium_impact	0,23	low_impact	-1,42	0,52	0,8	1,15	8,24	N	0,39	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4710	4710	T	C	MI.13268	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	241	81	S	P	Tcc/Ccc	-9,41	0	0	benign	0	neutral	0,2	neutral	4,51	deleterious	-3,47	deleterious	-3,82	medium_impact	2,12	neutral	0,87	neutral	0,41	deleterious	3,74	23,3	0,06	0,35	disease	0,86	disease	0,9	disease	0,61	disease	0,68	4	neutral	0,8	deleterious	0,6	neutral	-3	neutral	0,35	medium_impact	1,95	medium_impact	-0,13	medium_impact	0,64	0,14	0,8	1,15	8,24	N	0,32	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4710	4710	T	G	MI.13269	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	241	81	S	A	Tcc/Gcc	-9,41	0	0	benign	0,06	neutral	0,51	neutral	4,6	neutral	-0,47	neutral	-2,47	low_impact	1,64	neutral	0,91	neutral	0,58	deleterious	3,49	23,1	0,3	0,45	disease	0,61	disease	0,54	disease	0,57	disease	0,66	3	neutral	0,43	deleterious	0,73	neutral	-6	deleterious	0,6	medium_impact	0,3	medium_impact	0,22	medium_impact	0,24	0,28	0,8	1,15	8,24	N	0,28	N	0,38	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9150	9150	A	C	MI.1327	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	624	208	L	F	ttA/ttC	7,53	0,98	0	probably_damaging	1	neutral	0,59	neutral	4,34	neutral	1,21	deleterious	-2,73	low_impact	0,84	neutral	0,82	neutral	0,69	deleterious	3,54	23,1	0,35	0,65	NA	NA	disease	0,67	neutral	0,37	neutral	0,49	0	deleterious	0,99	neutral	0,3	neutral	-2	deleterious	0,84	low_impact	-3,6	medium_impact	0,38	medium_impact	-0,38	0,59	0,9	NA	NA	N	0,42	N	0,57	disease_causing	0,84	0,07	rs193303047	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4711	4711	C	T	MI.13270	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	242	81	S	F	tCc/tTc	0,03	0	0	benign	0,01	neutral	0,75	neutral	4,53	neutral	-2,87	deleterious	-5,17	low_impact	1,43	neutral	0,93	neutral	0,46	deleterious	4,11	23,7	0,05	0,35	disease	0,53	disease	0,84	disease	0,64	disease	0,74	5	neutral	0,23	deleterious	0,87	neutral	-6	deleterious	0,74	medium_impact	1,03	medium_impact	0,47	medium_impact	0,06	0,06	0,8	1,15	8,24	N	0,21	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4711	4711	C	A	MI.13271	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	242	81	S	Y	tCc/tAc	0,03	0	0	benign	0	neutral	1	neutral	4,53	deleterious	-3,38	deleterious	-5,12	low_impact	1,89	neutral	0,92	neutral	0,61	deleterious	3,88	23,5	0,04	0,35	disease	0,76	disease	0,81	disease	0,59	disease	0,7	4	neutral	0	deleterious	1	neutral	-6	neutral	0,34	medium_impact	1,95	high_impact	1,87	medium_impact	0,45	0,12	0,8	1,15	8,24	N	0,23	N	0,98	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4711	4711	C	G	MI.13272	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	242	81	S	C	tCc/tGc	0,03	0	0	possibly_damaging	0,7	neutral	0,18	neutral	4,51	deleterious	-4,87	deleterious	-4,27	medium_impact	2,38	neutral	0,89	neutral	0,39	deleterious	3,45	23	0,06	0,35	disease	0,84	disease	0,83	disease	0,61	disease	0,7	4	neutral	0,85	neutral	0,24	NA	0	deleterious	0,8	low_impact	-1,13	medium_impact	-0,16	medium_impact	0,86	0,17	0,8	1,15	8,24	N	0,43	N	0,59	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4713	4713	G	C	MI.13273	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	244	82	G	R	Gga/Cga	-2,5	0	0	probably_damaging	0,98	neutral	0,34	neutral	4,31	deleterious	-4,04	deleterious	-7,62	high_impact	3,77	neutral	0,78	damaging	0,26	deleterious	3,89	23,5	0,03	0,35	neutral	0,4	disease	0,9	disease	0,86	disease	0,74	5	neutral	0,98	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-2,34	medium_impact	0,05	high_impact	2,03	0,64	0,8	0,58	8,01	N	0,42	N	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4713	4713	G	T	MI.13274	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	244	82	G	W	Gga/Tga	-2,5	0	0	probably_damaging	1	neutral	0,18	neutral	4,26	deleterious	-7,22	deleterious	-7,65	high_impact	3,77	neutral	0,77	damaging	0,25	deleterious	4,33	24	0,05	0,35	disease	0,95	disease	0,88	disease	0,81	disease	0,65	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	-0,16	high_impact	2,03	0,11	0,8	0,58	8,01	N	0,4	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4714	4714	G	T	MI.13275	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	245	82	G	V	gGa/gTa	2,79	1	0	probably_damaging	0,99	neutral	0,53	neutral	4,29	deleterious	-4,18	deleterious	-8,59	medium_impact	2,87	neutral	0,68	neutral	0,32	deleterious	3,68	23,3	0,03	0,35	disease	0,76	disease	0,85	disease	0,79	disease	0,69	4	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,83	low_impact	-2,62	medium_impact	0,24	medium_impact	1,27	0,1	0,8	0,58	8,01	N	0,48	N	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4714	4714	G	A	MI.13276	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	245	82	G	E	gGa/gAa	2,79	1	0	possibly_damaging	0,47	neutral	0,27	neutral	4,35	deleterious	-3,38	deleterious	-7,59	medium_impact	2,29	neutral	0,85	neutral	0,33	deleterious	3,78	23,4	0,02	0,35	neutral	0,34	disease	0,89	disease	0,85	disease	0,72	4	neutral	0,7	neutral	0,4	NA	0	deleterious	0,69	medium_impact	-0,75	medium_impact	-0,03	medium_impact	0,78	0,23	0,8	0,58	8,01	N	0,5	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4714	4714	G	C	MI.13277	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	245	82	G	A	gGa/gCa	2,79	1	0	probably_damaging	0,92	neutral	0,51	neutral	4,33	neutral	-2,97	deleterious	-5,7	medium_impact	3,08	neutral	0,76	neutral	0,41	deleterious	3,04	22,4	0,1	0,4	neutral	0,42	disease	0,71	disease	0,75	disease	0,69	4	neutral	0,91	neutral	0,3	deleterious	1	deleterious	0,76	low_impact	-1,77	medium_impact	0,22	medium_impact	1,45	0,32	0,8	0,58	8,01	N	0,45	N	0,75	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4716	4716	C	A	MI.13278	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	247	83	Q	K	Caa/Aaa	-5,73	0	0	possibly_damaging	0,53	neutral	0,33	neutral	4,63	neutral	-0,16	deleterious	-3,36	medium_impact	2,48	neutral	0,85	neutral	0,38	deleterious	3,81	23,4	0,28	0,45	neutral	0,36	disease	0,83	disease	0,69	disease	0,67	3	neutral	0,66	neutral	0,4	NA	0	deleterious	0,65	medium_impact	-0,84	medium_impact	0,04	medium_impact	0,94	0,33	0,8	3,75	8,9	N	0,3	N	0,58	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4716	4716	C	G	MI.13279	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	247	83	Q	E	Caa/Gaa	-5,73	0	0	benign	0,34	neutral	0,33	neutral	4,65	neutral	0,07	neutral	-2,3	low_impact	1,62	neutral	0,9	neutral	0,61	deleterious	2,87	21,7	0,32	0,5	neutral	0,37	neutral	0,44	neutral	0,43	neutral	0,39	2	neutral	0,61	deleterious	0,5	neutral	-6	deleterious	0,53	medium_impact	-0,53	medium_impact	0,04	medium_impact	0,22	0,33	0,8	3,75	8,9	N	0,39	N	0,54	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9150	9150	A	T	MI.1328	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	624	208	L	F	ttA/ttT	7,53	0,98	0	probably_damaging	1	neutral	0,59	neutral	4,34	neutral	1,21	deleterious	-2,73	low_impact	0,84	neutral	0,82	neutral	0,69	deleterious	3,68	23,3	0,35	0,65	NA	NA	disease	0,67	neutral	0,37	neutral	0,49	0	deleterious	0,99	neutral	0,3	neutral	-2	deleterious	0,84	low_impact	-3,6	medium_impact	0,38	medium_impact	-0,38	0,59	0,9	NA	NA	N	0,43	N	0,57	disease_causing	0,84	0,07	rs193303047	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4717	4717	A	T	MI.13280	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	248	83	Q	L	cAa/cTa	0,03	0	0	benign	0,37	neutral	0,68	neutral	4,6	neutral	-0,69	deleterious	-6,14	medium_impact	2,31	neutral	0,92	neutral	0,65	deleterious	3,47	23	0,1	0,4	disease	0,74	disease	0,81	disease	0,57	disease	0,53	1	neutral	0,29	deleterious	0,66	neutral	-3	deleterious	0,62	medium_impact	-0,59	medium_impact	0,39	medium_impact	0,8	0,14	0,8	3,75	8,9	N	0,25	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4717	4717	A	C	MI.13281	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	248	83	Q	P	cAa/cCa	0,03	0	0	possibly_damaging	0,87	neutral	0,23	neutral	4,55	neutral	-2,32	deleterious	-5,16	medium_impact	2,48	neutral	0,74	neutral	0,32	deleterious	3,14	22,6	0,03	0,35	disease	0,73	disease	0,88	disease	0,69	disease	0,71	4	neutral	0,91	neutral	0,18	NA	0	deleterious	0,83	low_impact	-1,55	medium_impact	-0,08	medium_impact	0,94	0,17	0,8	3,75	8,9	N	0,29	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4717	4717	A	G	MI.13282	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	248	83	Q	R	cAa/cGa	0,03	0	0	possibly_damaging	0,59	neutral	0,36	neutral	4,59	neutral	-0,9	deleterious	-3,27	high_impact	3,63	neutral	0,84	neutral	0,39	deleterious	3,23	22,8	0,23	0,45	neutral	0,32	disease	0,83	disease	0,71	disease	0,7	4	neutral	0,66	neutral	0,39	deleterious	1	deleterious	0,66	medium_impact	-0,94	medium_impact	0,07	medium_impact	1,91	0,14	0,8	3,75	8,9	N	0,36	N	0,46	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4718	4718	A	T	MI.13283	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	249	83	Q	H	caA/caT	1,18	0	0	benign	0,04	neutral	0,54	neutral	4,56	neutral	-2,03	deleterious	-3,07	medium_impact	2,39	neutral	0,9	neutral	0,91	deleterious	2,36	18,57	0,27	0,45	neutral	0,42	disease	0,7	neutral	0,48	neutral	0,16	7	neutral	0,41	deleterious	0,75	neutral	-3	neutral	0,25	medium_impact	0,47	medium_impact	0,25	medium_impact	0,87	0,37	0,8	3,75	8,9	N	0,3	N	0,65	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4718	4718	A	C	MI.13284	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	249	83	Q	H	caA/caC	1,18	0	0	benign	0,04	neutral	0,54	neutral	4,56	neutral	-2,03	deleterious	-3,07	medium_impact	2,39	neutral	0,9	neutral	0,91	deleterious	2,27	17,98	0,27	0,45	neutral	0,42	disease	0,7	neutral	0,48	neutral	0,16	7	neutral	0,41	deleterious	0,75	neutral	-3	neutral	0,25	medium_impact	0,47	medium_impact	0,25	medium_impact	0,87	0,37	0,8	3,75	8,9	N	0,3	N	0,65	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4719	4719	T	G	MI.13285	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	250	84	W	G	Tga/Gga	-0,2	0	0	probably_damaging	1	neutral	0,35	neutral	4,54	neutral	-2,54	deleterious	-12,57	medium_impact	3,35	neutral	0,79	damaging	0,12	deleterious	3,79	23,4	0,06	0,35	disease	0,74	disease	0,8	disease	0,84	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,06	medium_impact	1,68	0,09	0,8	NA	NA	N	0,42	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4719	4719	T	C	MI.13286	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	250	84	W	R	Tga/Cga	-0,2	0	0	probably_damaging	1	neutral	0,35	neutral	4,54	neutral	-2,49	deleterious	-13,53	high_impact	3,9	neutral	0,77	damaging	0,1	deleterious	3,51	23,1	0,04	0,35	neutral	0,49	disease	0,89	disease	0,86	disease	0,75	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,06	high_impact	2,14	0,07	0,8	NA	NA	N	0,47	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4720	4720	G	C	MI.13287	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	251	84	W	S	tGa/tCa	5,55	1	0	probably_damaging	1	neutral	0,46	neutral	4,56	neutral	-1,52	deleterious	-13,53	medium_impact	2,13	neutral	0,78	damaging	0,14	deleterious	3,91	23,5	0,07	0,35	disease	0,53	disease	0,89	disease	0,82	disease	0,72	4	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,17	medium_impact	0,65	0,15	0,8	NA	NA	N	0,49	N	0,94	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4720	4720	G	T	MI.13288	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	251	84	W	L	tGa/tTa	5,55	1	0	probably_damaging	1	neutral	0,72	neutral	4,86	neutral	1,55	deleterious	-12,57	medium_impact	2,13	neutral	0,92	damaging	0,1	deleterious	4,12	23,8	0,1	0,4	disease	0,55	disease	0,82	disease	0,78	disease	0,7	4	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,44	medium_impact	0,65	0,12	0,8	NA	NA	N	0,5	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4721	4721	A	T	MI.13289	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	252	84	W	C	tgA/tgT	6,01	1	0	probably_damaging	1	neutral	0,17	neutral	4,56	neutral	-1,65	deleterious	-12,57	medium_impact	3,35	neutral	0,74	damaging	0,09	deleterious	4	23,6	0,05	0,35	disease	0,93	disease	0,9	disease	0,85	disease	0,65	3	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,17	medium_impact	1,68	0,12	0,8	NA	NA	P	0,63	P	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9151	9151	A	T	MI.1329	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	625	209	I	F	Atc/Ttc	-0,33	0,39	0	probably_damaging	0,99	deleterious	0,04	neutral	3,17	deleterious	-4,83	deleterious	-3,55	high_impact	4,49	damaging	0,55	neutral	0,45	deleterious	3,85	23,4	0,21	0,65	NA	NA	disease	0,91	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,9	low_impact	-2,65	medium_impact	-0,49	high_impact	2,75	0,64	0,9	48,67	8,76	N	0,51	P	0,97	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4721	4721	A	C	MI.13290	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	252	84	W	C	tgA/tgC	6,01	1	0	probably_damaging	1	neutral	0,17	neutral	4,56	neutral	-1,65	deleterious	-12,57	medium_impact	3,35	neutral	0,74	damaging	0,09	deleterious	3,91	23,5	0,05	0,35	disease	0,93	disease	0,9	disease	0,85	disease	0,65	3	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,17	medium_impact	1,68	0,12	0,8	NA	NA	P	0,62	P	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4722	4722	A	T	MI.13291	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	253	85	T	S	Acc/Tcc	-0,66	0	0	benign	0,11	neutral	0,5	neutral	4,77	neutral	1,47	neutral	-2,22	neutral_impact	0,76	neutral	0,84	neutral	0,94	deleterious	1,82	15,08	0,43	0,55	disease	0,51	neutral	0,32	neutral	0,24	neutral	0,36	3	neutral	0,42	deleterious	0,7	neutral	-6	neutral	0,23	medium_impact	0,03	medium_impact	0,21	medium_impact	-0,51	0,52	0,8	2,59	7,58	N	0,36	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4722	4722	A	C	MI.13292	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	253	85	T	P	Acc/Ccc	-0,66	0	0	possibly_damaging	0,86	neutral	0,25	neutral	4,59	neutral	-1,75	deleterious	-4,45	low_impact	1,86	neutral	0,75	neutral	0,31	deleterious	3,48	23,1	0,05	0,35	neutral	0,39	disease	0,78	disease	0,6	disease	0,69	4	neutral	0,9	neutral	0,2	neutral	-3	deleterious	0,71	low_impact	-1,52	medium_impact	-0,06	medium_impact	0,42	0,23	0,8	2,59	7,58	N	0,33	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4722	4722	A	G	MI.13293	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	253	85	T	A	Acc/Gcc	-0,66	0	0	benign	0,02	neutral	0,58	neutral	4,64	neutral	0	deleterious	-3,06	low_impact	1,46	neutral	0,94	neutral	0,81	deleterious	2,31	18,26	0,33	0,5	disease	0,61	neutral	0,34	neutral	0,43	disease	0,6	2	neutral	0,39	deleterious	0,78	neutral	-6	neutral	0,2	medium_impact	0,75	medium_impact	0,29	medium_impact	0,09	0,33	0,8	2,59	7,58	N	0,28	N	0,49	polymorphism	1	0,05	.	.	.	.	.	endometrial and ovarian tumors	.	.	.	.	.	.	.	.	.
chrM	4723	4723	C	A	MI.13294	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	254	85	T	N	aCc/aAc	-0,2	0	0	possibly_damaging	0,67	neutral	0,39	neutral	4,74	neutral	1,19	deleterious	-3,49	neutral_impact	0,74	neutral	0,86	neutral	0,9	deleterious	2,49	19,39	0,38	0,5	neutral	0,5	disease	0,58	neutral	0,26	neutral	0,23	5	neutral	0,7	neutral	0,36	neutral	-3	deleterious	0,67	low_impact	-1,08	medium_impact	0,1	medium_impact	-0,52	0,52	0,8	2,59	7,58	N	0,3	N	0,73	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4723	4723	C	G	MI.13295	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	254	85	T	S	aCc/aGc	-0,2	0	0	benign	0,11	neutral	0,5	neutral	4,77	neutral	1,47	neutral	-2,22	neutral_impact	0,76	neutral	0,84	neutral	0,94	deleterious	1,92	15,7	0,43	0,55	disease	0,51	neutral	0,32	neutral	0,24	neutral	0,36	3	neutral	0,42	deleterious	0,7	neutral	-6	neutral	0,23	medium_impact	0,03	medium_impact	0,21	medium_impact	-0,51	0,52	0,8	2,59	7,58	N	0,35	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4723	4723	C	T	MI.13296	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	254	85	T	I	aCc/aTc	-0,2	0	0	benign	0,09	neutral	0,44	neutral	4,61	neutral	-0,83	deleterious	-4,12	low_impact	1,86	neutral	0,94	neutral	0,5	deleterious	3,8	23,4	0,18	0,45	disease	0,83	disease	0,63	neutral	0,44	neutral	0,47	1	neutral	0,5	deleterious	0,68	neutral	-6	neutral	0,35	medium_impact	0,12	medium_impact	0,15	medium_impact	0,42	0,5	0,8	2,59	7,58	N	0,34	N	0,65	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4725	4725	A	G	MI.13297	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	256	86	M	V	Ata/Gta	-10,33	0	0	benign	0,01	neutral	0,58	neutral	4,73	neutral	1,6	neutral	1,08	neutral_impact	0,14	neutral	0,92	neutral	0,97	neutral	-0,67	0,09	0,25	0,45	neutral	0,44	neutral	0,28	neutral	0,37	neutral	0,42	2	neutral	0,4	deleterious	0,79	neutral	-6	neutral	0,15	medium_impact	1,03	medium_impact	0,29	low_impact	-1,03	0,36	0,8	5,76	8,39	N	0,33	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4725	4725	A	T	MI.13298	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	256	86	M	L	Ata/Tta	-10,33	0	0	benign	0	neutral	0,81	neutral	4,86	neutral	2,68	neutral	0,4	neutral_impact	-0,55	neutral	0,93	neutral	0,95	deleterious	-0,01	2,53	0,29	0,45	neutral	0,34	neutral	0,3	neutral	0,34	neutral	0,42	2	neutral	0,19	deleterious	0,91	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,56	low_impact	-1,61	0,28	0,8	5,76	8,39	N	0,34	N	0,1	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4725	4725	A	C	MI.13299	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	256	86	M	L	Ata/Cta	-10,33	0	0	benign	0	neutral	0,81	neutral	4,86	neutral	2,68	neutral	0,4	neutral_impact	-0,55	neutral	0,93	neutral	0,95	neutral	-0,19	1,15	0,29	0,45	neutral	0,34	neutral	0,3	neutral	0,34	neutral	0,42	2	neutral	0,19	deleterious	0,91	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,56	low_impact	-1,61	0,28	0,8	5,76	8,39	N	0,34	N	0,1	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8588	8588	T	A	MI.133	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	62	21	V	E	gTa/gAa	-2,42	0	0	probably_damaging	0,92	neutral	0,11	neutral	4,23	neutral	-2,99	deleterious	-3,05	low_impact	1,5	neutral	0,89	neutral	0,46	deleterious	3,42	23	0,17	0,65	disease	0,74	disease	0,63	disease	0,57	disease	0,73	5	neutral	0,97	neutral	0,1	neutral	-2	deleterious	0,74	low_impact	-1,76	medium_impact	-0,22	medium_impact	0,19	0,52	0,9	22,57	20,88	N	0,42	N	0,89	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9151	9151	A	C	MI.1330	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	625	209	I	L	Atc/Ctc	-0,33	0,39	0	probably_damaging	0,93	deleterious	0	neutral	3,63	neutral	-0,77	neutral	-1,77	medium_impact	2,33	damaging	0,54	neutral	0,47	deleterious	3,89	23,5	0,28	0,65	NA	NA	disease	0,82	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,8	low_impact	-1,82	low_impact	-1,4	medium_impact	0,9	0,57	0,9	48,67	8,76	N	0,34	N	0,83	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4726	4726	T	A	MI.13300	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	257	86	M	K	aTa/aAa	-0,2	0	0	benign	0,09	neutral	0,33	neutral	4,62	neutral	-1	deleterious	-3,68	low_impact	1,03	neutral	0,84	neutral	0,46	deleterious	1,97	16	0,03	0,35	neutral	0,38	disease	0,6	disease	0,73	disease	0,72	4	neutral	0,63	deleterious	0,62	neutral	-6	neutral	0,26	medium_impact	0,12	medium_impact	0,04	medium_impact	-0,28	0,21	0,8	5,76	8,39	N	0,31	N	0,51	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4726	4726	T	C	MI.13301	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	257	86	M	T	aTa/aCa	-0,2	0	0	benign	0	neutral	0,49	neutral	4,68	neutral	0,86	neutral	-1,96	neutral_impact	0,51	neutral	0,94	neutral	0,95	neutral	-0,2	1,08	0,11	0,4	disease	0,51	neutral	0,5	disease	0,56	neutral	0,46	1	neutral	0,51	deleterious	0,75	neutral	-6	neutral	0,22	medium_impact	1,95	medium_impact	0,2	medium_impact	-0,72	0,13	0,8	5,76	8,39	N	0,29	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4727	4727	A	T	MI.13302	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	258	86	M	I	atA/atT	2,33	0,05	0,01	benign	0	neutral	0,89	neutral	4,81	neutral	2,34	neutral	1,46	neutral_impact	-1,55	neutral	0,88	neutral	0,97	neutral	-1,23	0,01	0,3	0,45	neutral	0,43	neutral	0,07	neutral	0,23	neutral	0,29	4	neutral	0,1	deleterious	0,95	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,71	low_impact	-2,45	0,47	0,8	5,76	8,39	N	0,33	N	0,06	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4727	4727	A	C	MI.13303	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	258	86	M	I	atA/atC	2,33	0,05	0,01	benign	0	neutral	0,89	neutral	4,81	neutral	2,34	neutral	1,46	neutral_impact	-1,55	neutral	0,88	neutral	0,97	neutral	-1,26	0,01	0,3	0,45	neutral	0,43	neutral	0,07	neutral	0,23	neutral	0,29	4	neutral	0,1	deleterious	0,95	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,71	low_impact	-2,45	0,47	0,8	5,76	8,39	N	0,34	N	0,06	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4728	4728	A	C	MI.13304	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	259	87	T	P	Acc/Ccc	-4,58	0	0	benign	0,14	neutral	0,21	neutral	4,59	neutral	-1,84	deleterious	-2,88	low_impact	1,62	neutral	0,91	neutral	0,61	deleterious	1,92	15,69	0,04	0,35	disease	0,73	disease	0,73	disease	0,61	disease	0,6	2	neutral	0,76	deleterious	0,54	neutral	-6	deleterious	0,63	medium_impact	-0,08	medium_impact	-0,11	medium_impact	0,22	0,31	0,8	12,39	9,61	N	0,36	N	0,75	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4728	4728	A	T	MI.13305	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	259	87	T	S	Acc/Tcc	-4,58	0	0	benign	0,03	neutral	0,44	neutral	4,63	neutral	-0,14	neutral	-1,06	neutral_impact	0,3	neutral	0,83	neutral	0,97	neutral	-0,3	0,66	0,31	0,45	disease	0,57	neutral	0,34	neutral	0,26	disease	0,59	2	neutral	0,53	deleterious	0,71	neutral	-6	neutral	0,27	medium_impact	0,59	medium_impact	0,15	medium_impact	-0,89	0,48	0,8	12,39	9,61	N	0,37	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4728	4728	A	G	MI.13306	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	259	87	T	A	Acc/Gcc	-4,58	0	0	benign	0	neutral	0,52	neutral	4,59	neutral	0,35	neutral	-1,76	low_impact	1,66	neutral	0,95	neutral	0,82	neutral	-0,12	1,61	0,29	0,45	neutral	0,5	neutral	0,38	neutral	0,44	neutral	0,19	6	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,13	medium_impact	1,95	medium_impact	0,23	medium_impact	0,25	0,32	0,8	12,39	9,61	N	0,29	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4729	4729	C	T	MI.13307	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	260	87	T	I	aCc/aTc	0,03	0	0	benign	0	neutral	0,41	neutral	4,54	neutral	-1,56	neutral	-1,44	low_impact	1,31	neutral	0,9	neutral	0,93	deleterious	1,86	15,36	0,14	0,4	neutral	0,48	disease	0,55	neutral	0,34	neutral	0,46	1	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,26	medium_impact	1,95	medium_impact	0,12	medium_impact	-0,04	0,54	0,8	12,39	9,61	N	0,35	N	0,55	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4729	4729	C	G	MI.13308	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	260	87	T	S	aCc/aGc	0,03	0	0	benign	0,03	neutral	0,44	neutral	4,63	neutral	-0,14	neutral	-1,06	neutral_impact	0,3	neutral	0,83	neutral	0,97	neutral	-0,12	1,58	0,31	0,45	disease	0,57	neutral	0,34	neutral	0,26	disease	0,59	2	neutral	0,53	deleterious	0,71	neutral	-6	neutral	0,27	medium_impact	0,59	medium_impact	0,15	medium_impact	-0,89	0,48	0,8	12,39	9,61	N	0,39	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4729	4729	C	A	MI.13309	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	260	87	T	N	aCc/aAc	0,03	0	0	benign	0	neutral	0,35	neutral	4,61	neutral	-0,89	neutral	-1,98	low_impact	0,83	neutral	0,86	neutral	0,92	deleterious	1,92	15,72	0,32	0,5	neutral	0,5	disease	0,52	neutral	0,29	neutral	0,46	1	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,06	medium_impact	-0,45	0,45	0,8	12,39	9,61	N	0,39	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9151	9151	A	G	MI.1331	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	625	209	I	V	Atc/Gtc	-0,33	0,39	0	probably_damaging	0,93	neutral	0,08	neutral	3,39	neutral	-1,83	neutral	-0,89	medium_impact	3,13	neutral	0,63	neutral	0,52	deleterious	3,16	22,6	0,4	0,65	NA	NA	disease	0,68	disease	0,62	disease	0,66	3	neutral	0,98	neutral	0,08	deleterious	1	deleterious	0,79	low_impact	-1,82	medium_impact	-0,31	medium_impact	1,59	0,64	0,9	48,67	8,76	N	0,35	N	0,77	disease_causing	1	0,06	rs879206297	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4731	4731	A	T	MI.13310	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	262	88	N	Y	Aat/Tat	-1,12	0	0	possibly_damaging	0,86	neutral	1	neutral	4,53	neutral	-2,47	deleterious	-4,76	low_impact	1,34	neutral	0,92	neutral	0,81	deleterious	2,34	18,41	0,15	0,4	disease	0,75	disease	0,64	disease	0,55	disease	0,61	2	neutral	0,86	deleterious	0,57	neutral	-3	deleterious	0,76	low_impact	-1,52	high_impact	1,87	medium_impact	-0,02	0,31	0,8	19,31	10	N	0,26	N	0,67	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4731	4731	A	C	MI.13311	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	262	88	N	H	Aat/Cat	-1,12	0	0	possibly_damaging	0,86	neutral	0,54	neutral	4,54	neutral	-1,92	deleterious	-2,68	neutral_impact	0,73	neutral	0,9	neutral	0,9	neutral	1,66	14,19	0,32	0,5	disease	0,77	neutral	0,49	disease	0,52	disease	0,55	1	neutral	0,84	neutral	0,34	neutral	-3	deleterious	0,72	low_impact	-1,52	medium_impact	0,25	medium_impact	-0,53	0,16	0,8	19,31	10	N	0,32	N	0,15	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4731	4731	A	G	MI.13312	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	262	88	N	D	Aat/Gat	-1,12	0	0	benign	0,2	neutral	0,22	neutral	4,6	neutral	-0,28	deleterious	-2,87	low_impact	1,44	neutral	0,9	neutral	0,68	deleterious	0,74	9,07	0,4	0,5	disease	0,74	disease	0,54	disease	0,6	disease	0,58	1	neutral	0,74	deleterious	0,51	neutral	-6	deleterious	0,48	medium_impact	-0,25	medium_impact	-0,1	medium_impact	0,07	0,34	0,8	19,31	10	N	0,43	N	0,51	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4732	4732	A	T	MI.13313	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	263	88	N	I	aAt/aTt	0,03	0	0,05	possibly_damaging	0,68	neutral	0,41	neutral	4,58	deleterious	-3,02	deleterious	-5,73	low_impact	1,38	neutral	0,88	neutral	0,56	deleterious	2,62	20,3	0,16	0,45	disease	0,72	disease	0,75	disease	0,65	disease	0,71	4	neutral	0,69	neutral	0,37	neutral	-3	deleterious	0,72	low_impact	-1,1	medium_impact	0,12	medium_impact	0,02	0,23	0,8	19,31	10	N	0,31	N	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4732	4732	A	G	MI.13314	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	263	88	N	S	aAt/aGt	0,03	0	0,05	benign	0,01	neutral	0,42	neutral	4,6	neutral	-0,55	neutral	-2,22	neutral_impact	0,64	neutral	0,94	neutral	0,98	neutral	-0,41	0,36	0,4	0,5	disease	0,6	neutral	0,44	neutral	0,47	disease	0,6	2	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,17	medium_impact	1,03	medium_impact	0,13	medium_impact	-0,61	0,26	0,8	19,31	10	N	0,32	N	0,29	polymorphism	1	0,02	rs201854167	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4732	4732	A	C	MI.13315	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	263	88	N	T	aAt/aCt	0,03	0	0,05	benign	0,2	neutral	0,41	neutral	4,6	neutral	-1,25	deleterious	-3,29	low_impact	0,9	neutral	0,93	neutral	0,82	deleterious	0,39	6,5	0,23	0,45	disease	0,6	disease	0,55	neutral	0,47	neutral	0,46	1	neutral	0,51	deleterious	0,61	neutral	-6	neutral	0,4	medium_impact	-0,25	medium_impact	0,12	medium_impact	-0,39	0,31	0,8	19,31	10	N	0,35	N	0,29	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4733	4733	T	A	MI.13316	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	264	88	N	K	aaT/aaA	0,95	0	0,02	benign	0,29	neutral	0,32	neutral	4,65	neutral	-0,74	neutral	-1,4	neutral_impact	0,74	neutral	0,89	neutral	0,92	neutral	-0,2	1,09	0,36	0,5	neutral	0,49	neutral	0,48	neutral	0,5	neutral	0,45	1	neutral	0,61	deleterious	0,52	neutral	-6	deleterious	0,49	medium_impact	-0,44	medium_impact	0,03	medium_impact	-0,52	0,43	0,8	19,31	10	N	0,4	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4733	4733	T	G	MI.13317	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	264	88	N	K	aaT/aaG	0,95	0	0,02	benign	0,29	neutral	0,32	neutral	4,65	neutral	-0,74	neutral	-1,4	neutral_impact	0,74	neutral	0,89	neutral	0,92	neutral	-0,49	0,23	0,36	0,5	neutral	0,49	neutral	0,48	neutral	0,5	neutral	0,45	1	neutral	0,61	deleterious	0,52	neutral	-6	deleterious	0,49	medium_impact	-0,44	medium_impact	0,03	medium_impact	-0,52	0,43	0,8	19,31	10	N	0,41	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4734	4734	A	G	MI.13318	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	265	89	T	A	Act/Gct	-1,35	0	0	benign	0	neutral	0,53	neutral	4,63	neutral	-0,24	neutral	-0,54	low_impact	1,62	neutral	0,93	neutral	0,74	neutral	-0,12	1,6	0,28	0,45	neutral	0,46	neutral	0,24	neutral	0,46	neutral	0,44	1	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,14	medium_impact	1,95	medium_impact	0,24	medium_impact	0,22	0,34	0,8	17,58	9,79	N	0,32	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4734	4734	A	T	MI.13319	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	265	89	T	S	Act/Tct	-1,35	0	0	benign	0	neutral	0,56	neutral	4,62	neutral	-0,37	neutral	-0,43	neutral_impact	0,76	neutral	0,85	neutral	0,94	neutral	-0,47	0,26	0,42	0,55	neutral	0,49	neutral	0,25	neutral	0,43	neutral	0,4	2	neutral	0,43	deleterious	0,78	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,27	medium_impact	-0,51	0,57	0,8	17,58	9,79	N	0,34	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9152	9152	T	C	MI.1332	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	626	209	I	T	aTc/aCc	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	3,14	deleterious	-6,26	deleterious	-4,4	high_impact	4,49	neutral	0,62	neutral	0,53	deleterious	3,59	23,2	0,27	0,65	NA	NA	disease	0,83	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,65	low_impact	-1,4	high_impact	2,75	0,43	0,9	48,67	8,76	N	0,47	N	0,99	disease_causing	1	0,4	rs878853096	Uncertain significance	not_provided	RCV000224169.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	4734	4734	A	C	MI.13320	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	265	89	T	P	Act/Cct	-1,35	0	0	benign	0	neutral	0,27	neutral	4,61	neutral	-0,73	neutral	-1,3	low_impact	0,82	neutral	0,92	neutral	0,95	deleterious	0	2,58	0,05	0,35	disease	0,58	disease	0,66	neutral	0,43	neutral	0,22	6	neutral	0,73	deleterious	0,64	neutral	-6	neutral	0,24	medium_impact	1,95	medium_impact	-0,03	medium_impact	-0,45	0,28	0,8	17,58	9,79	N	0,35	N	0,66	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4735	4735	C	A	MI.13321	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	266	89	T	N	aCt/aAt	-7,11	0	0,01	benign	0	neutral	0,37	neutral	4,6	neutral	-1,18	neutral	-1,25	low_impact	0,96	neutral	0,95	neutral	0,86	deleterious	0,11	3,72	0,31	0,45	disease	0,5	neutral	0,43	neutral	0,3	neutral	0,25	5	neutral	0,63	deleterious	0,69	neutral	-6	neutral	0,17	medium_impact	1,95	medium_impact	0,08	medium_impact	-0,34	0,49	0,8	17,58	9,79	N	0,37	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4735	4735	C	G	MI.13322	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	266	89	T	S	aCt/aGt	-7,11	0	0,01	benign	0	neutral	0,56	neutral	4,62	neutral	-0,37	neutral	-0,43	neutral_impact	0,76	neutral	0,85	neutral	0,94	neutral	-0,11	1,67	0,42	0,55	neutral	0,49	neutral	0,25	neutral	0,43	neutral	0,4	2	neutral	0,43	deleterious	0,78	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,27	medium_impact	-0,51	0,57	0,8	17,58	9,79	N	0,31	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4735	4735	C	T	MI.13323	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	266	89	T	I	aCt/aTt	-7,11	0	0,01	benign	0	neutral	0,46	neutral	4,85	neutral	1,83	neutral	0,5	neutral_impact	0,38	neutral	0,95	neutral	0,97	neutral	-0,2	1,12	0,15	0,4	disease	0,66	neutral	0,33	neutral	0,31	disease	0,61	2	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,18	medium_impact	1,95	medium_impact	0,17	medium_impact	-0,83	0,54	0,8	17,58	9,79	N	0,4	N	0,16	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4737	4737	A	T	MI.13324	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	268	90	T	S	Acc/Tcc	-4,11	0	0	benign	0	neutral	0,45	neutral	4,68	neutral	-0,94	neutral	-0,13	neutral_impact	0,36	neutral	0,84	neutral	0,97	neutral	1,5	13,31	0,33	0,5	disease	0,56	neutral	0,18	neutral	0,19	neutral	0,4	2	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	0,16	medium_impact	-0,84	0,54	0,8	12,39	9,68	N	0,49	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4737	4737	A	C	MI.13325	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	268	90	T	P	Acc/Ccc	-4,11	0	0	benign	0	neutral	0,22	neutral	4,59	neutral	-2,15	neutral	-0,9	low_impact	1,46	neutral	0,95	neutral	0,89	deleterious	2,37	18,63	0,05	0,35	disease	0,72	disease	0,72	neutral	0,43	disease	0,55	1	neutral	0,78	deleterious	0,61	neutral	-6	neutral	0,25	medium_impact	1,95	medium_impact	-0,1	medium_impact	0,09	0,29	0,8	12,39	9,68	N	0,34	N	0,36	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4737	4737	A	G	MI.13326	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	268	90	T	A	Acc/Gcc	-4,11	0	0	benign	0	neutral	0,54	neutral	4,68	neutral	0,09	neutral	-0,73	low_impact	1,56	neutral	0,9	neutral	0,81	deleterious	2,04	16,46	0,26	0,45	disease	0,53	neutral	0,4	neutral	0,44	neutral	0,39	2	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	0,25	medium_impact	0,17	0,21	0,8	12,39	9,68	N	0,3	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4738	4738	C	T	MI.13327	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	269	90	T	I	aCc/aTc	-4,11	0	0	benign	0	neutral	0,42	neutral	4,66	neutral	-1,66	neutral	-0,85	low_impact	1,76	neutral	0,91	neutral	0,87	deleterious	2,02	16,33	0,15	0,4	disease	0,57	disease	0,63	neutral	0,46	neutral	0,49	0	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,19	medium_impact	1,95	medium_impact	0,13	medium_impact	0,34	0,52	0,8	12,39	9,68	N	0,27	N	0,16	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4738	4738	C	A	MI.13328	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	269	90	T	N	aCc/aAc	-4,11	0	0	benign	0,06	neutral	0,34	neutral	4,67	neutral	-2,19	neutral	-0,26	low_impact	0,94	neutral	0,85	neutral	0,95	deleterious	1,85	15,26	0,3	0,45	neutral	0,47	neutral	0,47	neutral	0,29	neutral	0,49	0	neutral	0,62	deleterious	0,64	neutral	-6	deleterious	0,49	medium_impact	0,3	medium_impact	0,05	medium_impact	-0,35	0,47	0,8	12,39	9,68	N	0,45	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4738	4738	C	G	MI.13329	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	269	90	T	S	aCc/aGc	-4,11	0	0	benign	0	neutral	0,45	neutral	4,68	neutral	-0,94	neutral	-0,13	neutral_impact	0,36	neutral	0,84	neutral	0,97	neutral	1,19	11,67	0,33	0,5	disease	0,56	neutral	0,18	neutral	0,19	neutral	0,4	2	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	0,16	medium_impact	-0,84	0,54	0,8	12,39	9,68	N	0,49	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9152	9152	T	G	MI.1333	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	626	209	I	S	aTc/aGc	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	3,14	deleterious	-7,61	deleterious	-5,29	high_impact	4,14	damaging	0,56	neutral	0,6	deleterious	4,4	24,1	0,18	0,65	NA	NA	disease	0,92	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,65	low_impact	-1,4	high_impact	2,45	0,35	0,9	48,67	8,76	N	0,42	N	0,98	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4740	4740	A	T	MI.13330	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	271	91	N	Y	Aat/Tat	-8,95	0	0	probably_damaging	0,96	neutral	1	neutral	4,5	deleterious	-3,24	deleterious	-6,75	low_impact	1,82	neutral	0,91	neutral	0,66	deleterious	3,55	23,1	0,16	0,45	neutral	0,4	disease	0,8	neutral	0,4	neutral	0,49	0	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,73	low_impact	-2,06	high_impact	1,87	medium_impact	0,39	0,24	0,8	1,15	7,43	N	0,25	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4740	4740	A	C	MI.13331	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	271	91	N	H	Aat/Cat	-8,95	0	0	probably_damaging	0,96	neutral	0,55	neutral	4,51	neutral	-2,59	deleterious	-4,08	neutral_impact	0,32	neutral	0,82	neutral	0,94	deleterious	1,81	15,07	0,39	0,5	disease	0,63	neutral	0,28	neutral	0,31	disease	0,57	1	neutral	0,96	neutral	0,3	neutral	-2	deleterious	0,7	low_impact	-2,06	medium_impact	0,26	medium_impact	-0,88	0,1	0,8	1,15	7,43	N	0,29	N	0,62	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4740	4740	A	G	MI.13332	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	271	91	N	D	Aat/Gat	-8,95	0	0	benign	0,03	neutral	0,21	neutral	4,55	neutral	-1,29	deleterious	-3,71	neutral_impact	0,72	neutral	0,82	neutral	0,95	deleterious	2,45	19,14	0,53	0,6	disease	0,59	disease	0,62	neutral	0,35	neutral	0,27	5	neutral	0,78	deleterious	0,59	neutral	-6	neutral	0,22	medium_impact	0,59	medium_impact	-0,11	medium_impact	-0,54	0,32	0,8	1,15	7,43	N	0,36	N	0,8	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4741	4741	A	G	MI.13333	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	272	91	N	S	aAt/aGt	0,03	0	0	benign	0,06	neutral	0,41	neutral	4,59	neutral	-0,57	deleterious	-3,71	low_impact	1,01	neutral	0,85	neutral	0,98	neutral	1,79	14,9	0,51	0,6	disease	0,6	disease	0,57	neutral	0,31	neutral	0,28	4	neutral	0,55	deleterious	0,68	neutral	-6	neutral	0,28	medium_impact	0,3	medium_impact	0,12	medium_impact	-0,29	0,19	0,8	1,15	7,43	N	0,33	N	0,07	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4741	4741	A	C	MI.13334	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	272	91	N	T	aAt/aCt	0,03	0	0	possibly_damaging	0,54	neutral	0,39	neutral	4,64	neutral	-0,07	deleterious	-4,83	low_impact	1,06	neutral	0,88	neutral	0,73	deleterious	3,34	22,9	0,33	0,5	disease	0,71	disease	0,68	neutral	0,27	neutral	0,3	4	neutral	0,61	neutral	0,43	neutral	-3	deleterious	0,64	medium_impact	-0,86	medium_impact	0,1	medium_impact	-0,25	0,24	0,8	1,15	7,43	N	0,36	N	0,65	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4741	4741	A	T	MI.13335	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	272	91	N	I	aAt/aTt	0,03	0	0	probably_damaging	0,92	neutral	0,4	neutral	4,51	neutral	-2,68	deleterious	-7,62	medium_impact	1,94	neutral	0,9	neutral	0,48	deleterious	3,94	23,5	0,17	0,45	disease	0,67	disease	0,88	disease	0,53	disease	0,73	5	neutral	0,92	neutral	0,24	deleterious	1	deleterious	0,79	low_impact	-1,77	medium_impact	0,11	medium_impact	0,49	0,17	0,8	1,15	7,43	N	0,37	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4742	4742	T	G	MI.13336	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	273	91	N	K	aaT/aaG	0,95	0	0,01	possibly_damaging	0,62	neutral	0,29	neutral	4,67	neutral	0,27	deleterious	-4,94	medium_impact	2	neutral	0,89	neutral	0,38	deleterious	3,91	23,5	0,42	0,55	disease	0,53	disease	0,8	disease	0,6	disease	0,71	4	neutral	0,74	neutral	0,34	NA	0	deleterious	0,69	medium_impact	-0,99	medium_impact	-0,01	medium_impact	0,54	0,39	0,8	1,15	7,43	N	0,39	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4742	4742	T	A	MI.13337	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	273	91	N	K	aaT/aaA	0,95	0	0,01	possibly_damaging	0,62	neutral	0,29	neutral	4,67	neutral	0,27	deleterious	-4,94	medium_impact	2	neutral	0,89	neutral	0,38	deleterious	4,18	23,8	0,42	0,55	disease	0,53	disease	0,8	disease	0,6	disease	0,71	4	neutral	0,74	neutral	0,34	NA	0	deleterious	0,69	medium_impact	-0,99	medium_impact	-0,01	medium_impact	0,54	0,39	0,8	1,15	7,43	N	0,39	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4743	4743	C	A	MI.13338	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	274	92	Q	K	Caa/Aaa	-0,89	0	0	benign	0,04	neutral	0,46	neutral	4,66	neutral	0,4	neutral	-1,26	neutral_impact	0,19	neutral	0,86	neutral	0,72	neutral	1,11	11,26	0,33	0,5	neutral	0,49	disease	0,73	neutral	0,5	neutral	0,38	2	neutral	0,5	deleterious	0,71	neutral	-6	neutral	0,24	medium_impact	0,47	medium_impact	0,17	medium_impact	-0,98	0,31	0,8	12,68	9,01	N	0,23	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4743	4743	C	G	MI.13339	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	274	92	Q	E	Caa/Gaa	-0,89	0	0	benign	0,33	neutral	0,44	neutral	4,68	neutral	0,91	neutral	-0,91	neutral_impact	0,7	neutral	0,89	neutral	0,75	deleterious	0,09	3,55	0,37	0,5	neutral	0,49	disease	0,71	neutral	0,49	neutral	0,38	3	neutral	0,48	deleterious	0,56	neutral	-6	deleterious	0,48	medium_impact	-0,52	medium_impact	0,15	medium_impact	-0,56	0,43	0,8	12,68	9,01	N	0,32	N	0,47	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9152	9152	T	A	MI.1334	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	626	209	I	N	aTc/aAc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	3,13	deleterious	-8,46	deleterious	-6,21	high_impact	4,14	damaging	0,54	neutral	0,49	deleterious	4,74	24,7	0,2	0,65	NA	NA	disease	0,91	disease	0,72	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	high_impact	2,45	0,41	0,9	48,67	8,76	N	0,43	N	1	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4744	4744	A	G	MI.13340	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	275	92	Q	R	cAa/cGa	-0,43	0	0	possibly_damaging	0,44	neutral	0,43	neutral	4,64	neutral	-0,02	neutral	-1,62	medium_impact	2,02	neutral	0,89	neutral	0,51	neutral	1,64	14,08	0,31	0,45	disease	0,53	disease	0,83	disease	0,52	disease	0,7	4	neutral	0,53	deleterious	0,5	NA	0	deleterious	0,6	medium_impact	-0,7	medium_impact	0,14	medium_impact	0,56	0,11	0,8	12,68	9,01	N	0,35	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4744	4744	A	C	MI.13341	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	275	92	Q	P	cAa/cCa	-0,43	0	0	benign	0,04	neutral	0,33	neutral	4,66	neutral	0,57	neutral	0,8	neutral_impact	-1,32	neutral	0,92	neutral	0,98	neutral	-1,43	0	0,07	0,35	neutral	0,48	neutral	0,23	neutral	0,4	neutral	0,38	2	neutral	0,65	deleterious	0,65	neutral	-6	neutral	0,18	medium_impact	0,47	medium_impact	0,04	low_impact	-2,26	0,38	0,8	12,68	9,01	N	0,38	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4744	4744	A	T	MI.13342	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	275	92	Q	L	cAa/cTa	-0,43	0	0	possibly_damaging	0,61	neutral	0,76	neutral	4,84	neutral	2,77	deleterious	-3,06	neutral_impact	0,57	neutral	0,9	neutral	0,68	deleterious	0,81	9,53	0,12	0,4	neutral	0,39	disease	0,75	neutral	0,45	neutral	0,42	2	neutral	0,52	deleterious	0,58	neutral	-3	deleterious	0,6	medium_impact	-0,98	medium_impact	0,49	medium_impact	-0,67	0,07	0,8	12,68	9,01	N	0,29	N	0,81	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4745	4745	A	C	MI.13343	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	276	92	Q	H	caA/caC	-0,2	0	0,02	probably_damaging	0,95	neutral	0,56	neutral	4,63	neutral	-0,82	neutral	-0,91	neutral_impact	0,78	neutral	0,89	neutral	0,94	deleterious	1,98	16,05	0,3	0,45	disease	0,74	disease	0,53	neutral	0,33	neutral	0,3	4	neutral	0,94	neutral	0,31	neutral	-2	deleterious	0,75	low_impact	-1,97	medium_impact	0,27	medium_impact	-0,49	0,38	0,8	12,68	9,01	N	0,33	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4745	4745	A	T	MI.13344	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	276	92	Q	H	caA/caT	-0,2	0	0,02	probably_damaging	0,95	neutral	0,56	neutral	4,63	neutral	-0,82	neutral	-0,91	neutral_impact	0,78	neutral	0,89	neutral	0,94	deleterious	2,11	16,94	0,3	0,45	disease	0,74	disease	0,53	neutral	0,33	neutral	0,3	4	neutral	0,94	neutral	0,31	neutral	-2	deleterious	0,75	low_impact	-1,97	medium_impact	0,27	medium_impact	-0,49	0,38	0,8	12,68	9,01	N	0,33	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4746	4746	T	G	MI.13345	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	277	93	Y	D	Tac/Gac	-4,35	0	0	benign	0,3	neutral	0,29	neutral	4,62	deleterious	-3,51	neutral	-1,55	low_impact	1,49	neutral	0,88	neutral	0,41	deleterious	2,48	19,35	0,05	0,35	disease	0,96	disease	0,71	disease	0,58	disease	0,83	7	neutral	0,65	deleterious	0,5	neutral	-6	deleterious	0,59	medium_impact	-0,46	medium_impact	-0,01	medium_impact	0,11	0,09	0,8	7,49	8,66	N	0,31	N	0,71	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4746	4746	T	A	MI.13346	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	277	93	Y	N	Tac/Aac	-4,35	0	0	benign	0,3	neutral	0,47	neutral	4,63	deleterious	-3,04	neutral	-0,88	neutral_impact	0,29	neutral	0,9	neutral	0,82	deleterious	2,53	19,68	0,1	0,4	disease	0,94	disease	0,57	neutral	0,45	disease	0,76	5	neutral	0,44	deleterious	0,59	neutral	-6	deleterious	0,55	medium_impact	-0,46	medium_impact	0,18	medium_impact	-0,9	0,08	0,8	7,49	8,66	N	0,34	N	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4746	4746	T	C	MI.13347	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	277	93	Y	H	Tac/Cac	-4,35	0	0	possibly_damaging	0,77	neutral	0,44	neutral	4,63	neutral	-1,9	neutral	-1,27	low_impact	0,86	neutral	0,89	neutral	0,51	neutral	1,58	13,75	0,22	0,45	disease	0,94	neutral	0,49	neutral	0,32	disease	0,73	5	neutral	0,76	neutral	0,34	neutral	-3	deleterious	0,73	low_impact	-1,28	medium_impact	0,15	medium_impact	-0,42	0,16	0,8	7,49	8,66	N	0,34	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4747	4747	A	C	MI.13348	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	278	93	Y	S	tAc/tCc	-5,5	0	0	benign	0,12	neutral	0,55	neutral	4,66	neutral	-1,76	neutral	0,08	neutral_impact	0,31	neutral	0,88	neutral	0,91	neutral	1,73	14,59	0,07	0,35	disease	0,85	disease	0,54	neutral	0,44	disease	0,63	3	neutral	0,36	deleterious	0,72	neutral	-6	neutral	0,37	medium_impact	-0,01	medium_impact	0,26	medium_impact	-0,88	0,15	0,8	7,49	8,66	N	0,28	N	0,56	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4747	4747	A	T	MI.13349	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	278	93	Y	F	tAc/tTc	-5,5	0	0	benign	0	neutral	0,72	neutral	4,79	neutral	0,32	neutral	0,48	neutral_impact	0,06	neutral	0,9	neutral	0,89	deleterious	0,85	9,75	0,35	0,5	disease	0,62	neutral	0,46	neutral	0,22	disease	0,59	2	neutral	0,27	deleterious	0,86	neutral	-6	neutral	0,19	medium_impact	1,95	medium_impact	0,44	low_impact	-1,09	0,34	0,8	7,49	8,66	N	0,31	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9153	9153	C	A	MI.1335	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	627	209	I	M	atC/atA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	3,18	deleterious	-4,45	deleterious	-2,66	high_impact	3,94	damaging	0,59	neutral	0,59	deleterious	3,98	23,6	0,29	0,65	NA	NA	disease	0,81	disease	0,71	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,6	low_impact	-1,4	high_impact	2,28	0,7	0,9	48,67	8,76	N	0,46	N	0,75	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4747	4747	A	G	MI.13350	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	278	93	Y	C	tAc/tGc	-5,5	0	0	possibly_damaging	0,77	neutral	0,16	neutral	4,63	deleterious	-3,1	neutral	-0,16	low_impact	1,83	neutral	0,84	neutral	0,41	deleterious	1,95	15,91	0,05	0,35	disease	0,94	disease	0,75	neutral	0,46	disease	0,79	6	neutral	0,89	neutral	0,2	neutral	-3	deleterious	0,74	low_impact	-1,28	medium_impact	-0,19	medium_impact	0,4	0,01	0,8	7,49	8,66	N	0,38	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4749	4749	T	A	MI.13351	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	280	94	S	T	Tca/Aca	-8,72	0	0	benign	0,02	neutral	0,6	neutral	4,56	neutral	-1,31	neutral	-0,44	neutral_impact	0,74	neutral	0,9	neutral	0,93	deleterious	2,39	18,75	0,27	0,45	neutral	0,25	disease	0,65	neutral	0,28	neutral	0,24	5	neutral	0,37	deleterious	0,79	neutral	-6	neutral	0,17	medium_impact	0,75	medium_impact	0,31	medium_impact	-0,52	0,55	0,8	10,95	9,28	N	0,32	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4749	4749	T	G	MI.13352	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	280	94	S	A	Tca/Gca	-8,72	0	0	benign	0,19	neutral	0,81	neutral	4,63	neutral	-0,14	neutral	0,89	neutral_impact	-0,6	neutral	0,91	neutral	0,97	deleterious	0,81	9,55	0,26	0,45	neutral	0,21	neutral	0,22	neutral	0,22	neutral	0,42	2	neutral	0,11	deleterious	0,81	neutral	-6	neutral	0,25	medium_impact	-0,22	medium_impact	0,56	low_impact	-1,65	0,39	0,8	10,95	9,28	N	0,29	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4749	4749	T	C	MI.13353	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	280	94	S	P	Tca/Cca	-8,72	0	0	benign	0,01	neutral	0,33	neutral	4,55	neutral	-1,64	neutral	-1,45	neutral_impact	0,44	neutral	0,89	neutral	0,98	deleterious	2,66	20,6	0,07	0,35	neutral	0,48	disease	0,77	neutral	0,39	neutral	0,23	5	neutral	0,66	deleterious	0,66	neutral	-6	neutral	0,25	medium_impact	1,03	medium_impact	0,04	medium_impact	-0,77	0,21	0,8	10,95	9,28	N	0,33	N	0,03	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4750	4750	C	G	MI.13354	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	281	94	S	W	tCa/tGa	-2,5	0	0	possibly_damaging	0,89	deleterious	0,02	neutral	4,52	neutral	-2,58	deleterious	-3,89	medium_impact	2,73	neutral	0,86	neutral	0,47	deleterious	4,23	23,9	0,06	0,35	disease	0,79	disease	0,89	disease	0,66	disease	0,72	4	deleterious	0,99	neutral	0,07	deleterious	4	deleterious	0,78	low_impact	-1,63	medium_impact	-0,73	medium_impact	1,15	0,13	0,8	10,95	9,28	N	0,35	N	0,63	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4750	4750	C	T	MI.13355	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	281	94	S	L	tCa/tTa	-2,5	0	0	benign	0,01	neutral	0,44	neutral	4,77	neutral	0,98	neutral	-2,12	low_impact	1,12	neutral	0,9	neutral	0,85	deleterious	3,35	22,9	0,1	0,4	neutral	0,23	disease	0,85	neutral	0,48	neutral	0,5	0	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,17	medium_impact	1,03	medium_impact	0,15	medium_impact	-0,2	0,43	0,8	10,95	9,28	N	0,32	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4752	4752	T	C	MI.13356	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	283	95	S	P	Tca/Cca	-6,88	0	0	benign	0,05	neutral	0,21	neutral	4,48	neutral	-1,65	deleterious	-3,1	medium_impact	2,06	neutral	0,9	neutral	0,62	deleterious	3,8	23,4	0,05	0,35	disease	0,73	disease	0,91	disease	0,65	disease	0,6	2	neutral	0,77	deleterious	0,58	neutral	-3	neutral	0,33	medium_impact	0,37	medium_impact	-0,11	medium_impact	0,59	0,28	0,8	4,32	8,5	N	0,37	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4752	4752	T	A	MI.13357	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	283	95	S	T	Tca/Aca	-6,88	0	0	benign	0,06	neutral	0,41	neutral	4,54	neutral	-0,81	neutral	-1,9	neutral_impact	0,66	neutral	0,9	neutral	0,77	deleterious	2,48	19,32	0,28	0,45	neutral	0,41	disease	0,63	neutral	0,27	neutral	0,24	5	neutral	0,55	deleterious	0,68	neutral	-6	neutral	0,21	medium_impact	0,3	medium_impact	0,12	medium_impact	-0,59	0,48	0,8	4,32	8,5	N	0,39	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4752	4752	T	G	MI.13358	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	283	95	S	A	Tca/Gca	-6,88	0	0	benign	0,03	neutral	0,52	neutral	4,56	neutral	0,38	neutral	-2,04	low_impact	1,33	neutral	0,93	neutral	0,82	deleterious	2,47	19,25	0,28	0,45	neutral	0,33	disease	0,62	neutral	0,32	neutral	0,24	5	neutral	0,44	deleterious	0,75	neutral	-6	neutral	0,18	medium_impact	0,59	medium_impact	0,23	medium_impact	-0,03	0,39	0,8	4,32	8,5	N	0,29	N	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4753	4753	C	T	MI.13359	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	284	95	S	L	tCa/tTa	-1,35	0	0	possibly_damaging	0,54	neutral	0,67	neutral	4,63	neutral	0,74	deleterious	-4,37	neutral_impact	0,76	neutral	0,86	neutral	0,89	deleterious	3,3	22,9	0,09	0,35	neutral	0,22	disease	0,86	neutral	0,35	neutral	0,23	6	neutral	0,46	deleterious	0,57	neutral	-3	deleterious	0,54	medium_impact	-0,86	medium_impact	0,38	medium_impact	-0,51	0,41	0,8	4,32	8,5	N	0,25	N	0,54	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9153	9153	C	G	MI.1336	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	627	209	I	M	atC/atG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	3,18	deleterious	-4,45	deleterious	-2,66	high_impact	3,94	damaging	0,59	neutral	0,59	deleterious	3,54	23,1	0,29	0,65	NA	NA	disease	0,81	disease	0,71	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,6	low_impact	-1,4	high_impact	2,28	0,7	0,9	48,67	8,76	N	0,46	N	0,75	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4753	4753	C	G	MI.13360	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	284	95	S	W	tCa/tGa	-1,35	0	0	probably_damaging	0,98	neutral	0,19	neutral	4,54	deleterious	-3,71	deleterious	-5,6	medium_impact	2,68	neutral	0,88	neutral	0,42	deleterious	4,16	23,8	0,06	0,35	disease	0,83	disease	0,91	disease	0,59	disease	0,68	4	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,81	low_impact	-2,34	medium_impact	-0,14	medium_impact	1,11	0,15	0,8	4,32	8,5	N	0,37	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4755	4755	T	G	MI.13361	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	286	96	L	V	Tta/Gta	-20	0	0	benign	0,26	neutral	0,39	neutral	4,39	neutral	-1,13	neutral	-0,28	low_impact	0,8	neutral	0,93	neutral	0,93	neutral	-0,09	1,82	0,28	0,45	disease	0,73	disease	0,57	neutral	0,33	neutral	0,44	1	neutral	0,53	deleterious	0,57	neutral	-6	deleterious	0,43	medium_impact	-0,38	medium_impact	0,1	medium_impact	-0,47	0,66	0,8	10,09	9,41	N	0,37	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4755	4755	T	A	MI.13362	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	286	96	L	M	Tta/Ata	-20	0	0	benign	0,17	neutral	0,38	neutral	4,3	deleterious	-3,44	neutral	-0,1	neutral_impact	-0,26	neutral	0,93	neutral	0,85	neutral	1,78	14,87	0,25	0,45	disease	0,73	neutral	0,43	neutral	0,3	disease	0,62	2	neutral	0,55	deleterious	0,61	neutral	-6	neutral	0,31	medium_impact	-0,17	medium_impact	0,09	low_impact	-1,36	0,48	0,8	10,09	9,41	N	0,41	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4756	4756	T	G	MI.13363	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	287	96	L	W	tTa/tGa	-2,27	0	0	probably_damaging	0,92	neutral	0,05	neutral	4,25	deleterious	-5,13	neutral	-2,34	low_impact	1,78	neutral	0,82	neutral	0,44	deleterious	2,32	18,29	0,05	0,35	disease	0,97	disease	0,76	disease	0,51	disease	0,78	6	deleterious	0,99	neutral	0,07	neutral	-2	deleterious	0,8	low_impact	-1,77	medium_impact	-0,5	medium_impact	0,35	0,33	0,8	10,09	9,41	N	0,34	N	0,69	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4756	4756	T	C	MI.13364	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	287	96	L	S	tTa/tCa	-2,27	0	0	benign	0,04	neutral	0,35	neutral	4,31	deleterious	-4,14	neutral	-1,46	neutral_impact	0,6	neutral	0,91	neutral	0,86	deleterious	0,41	6,67	0,04	0,35	disease	0,84	disease	0,7	neutral	0,36	disease	0,57	1	neutral	0,62	deleterious	0,66	neutral	-6	neutral	0,28	medium_impact	0,47	medium_impact	0,06	medium_impact	-0,64	0,33	0,8	10,09	9,41	N	0,34	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4757	4757	A	C	MI.13365	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	288	96	L	F	ttA/ttC	-1,58	0	0	possibly_damaging	0,69	neutral	0,34	neutral	4,45	deleterious	-3,08	neutral	-0,42	low_impact	0,91	neutral	0,93	neutral	0,86	neutral	1,14	11,44	0,19	0,45	disease	0,68	disease	0,62	neutral	0,34	neutral	0,44	1	neutral	0,74	neutral	0,33	neutral	-3	deleterious	0,66	low_impact	-1,12	medium_impact	0,05	medium_impact	-0,38	0,63	0,8	10,09	9,41	N	0,42	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4757	4757	A	T	MI.13366	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	288	96	L	F	ttA/ttT	-1,58	0	0	possibly_damaging	0,69	neutral	0,34	neutral	4,45	deleterious	-3,08	neutral	-0,42	low_impact	0,91	neutral	0,93	neutral	0,86	neutral	1,25	12,02	0,19	0,45	disease	0,68	disease	0,62	neutral	0,34	neutral	0,44	1	neutral	0,74	neutral	0,33	neutral	-3	deleterious	0,66	low_impact	-1,12	medium_impact	0,05	medium_impact	-0,38	0,63	0,8	10,09	9,41	N	0,45	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4758	4758	A	G	MI.13367	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	289	97	M	V	Ata/Gta	-9,87	0	0	benign	0,01	neutral	0,54	neutral	4,69	neutral	-0,28	neutral	-0,95	low_impact	0,94	neutral	0,94	neutral	0,9	neutral	1,36	12,56	0,18	0,45	disease	0,67	disease	0,72	neutral	0,5	neutral	0,28	4	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,23	medium_impact	1,03	medium_impact	0,25	medium_impact	-0,35	0,36	0,8	0,58	8,19	N	0,25	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4758	4758	A	C	MI.13368	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	289	97	M	L	Ata/Cta	-9,87	0	0	benign	0,02	neutral	1	neutral	4,97	neutral	2,14	neutral	-0,43	neutral_impact	-0,86	neutral	0,94	neutral	0,99	deleterious	0,36	6,29	0,18	0,45	disease	0,51	neutral	0,48	neutral	0,4	neutral	0,36	3	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,2	medium_impact	0,75	high_impact	1,87	low_impact	-1,87	0,38	0,8	0,58	8,19	N	0,29	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4758	4758	A	T	MI.13369	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	289	97	M	L	Ata/Tta	-9,87	0	0	benign	0,02	neutral	1	neutral	4,97	neutral	2,14	neutral	-0,43	neutral_impact	-0,86	neutral	0,94	neutral	0,99	deleterious	0,43	6,87	0,18	0,45	disease	0,51	neutral	0,48	neutral	0,4	neutral	0,36	3	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,2	medium_impact	0,75	high_impact	1,87	low_impact	-1,87	0,38	0,8	0,58	8,19	N	0,29	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9154	9154	C	A	MI.1337	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	628	210	Q	K	Caa/Aaa	-2,88	0	0	probably_damaging	0,97	deleterious	0	neutral	2,97	deleterious	-6,06	deleterious	-3,54	high_impact	4,24	damaging	0,6	damaging	0,14	deleterious	4,04	23,7	0,2	0,65	NA	NA	disease	0,93	disease	0,8	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,9	low_impact	-2,19	low_impact	-1,4	high_impact	2,54	0,55	0,9	49,56	8,86	N	0,44	N	0,99	disease_causing	0,92	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4759	4759	T	A	MI.13370	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	290	97	M	K	aTa/aAa	-3,88	0	0	benign	0,16	neutral	0,32	neutral	4,56	deleterious	-3,18	deleterious	-4,25	medium_impact	2,56	neutral	0,87	neutral	0,35	deleterious	3,91	23,5	0,03	0,35	disease	0,78	disease	0,89	disease	0,74	disease	0,75	5	neutral	0,62	deleterious	0,58	neutral	-3	deleterious	0,54	medium_impact	-0,14	medium_impact	0,03	medium_impact	1,01	0,28	0,8	0,58	8,19	N	0,36	N	0,92	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4759	4759	T	C	MI.13371	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	290	97	M	T	aTa/aCa	-3,88	0	0	benign	0,01	neutral	0,44	neutral	4,59	neutral	-1,71	deleterious	-3,14	neutral_impact	0,8	neutral	0,92	neutral	0,95	neutral	1,51	13,35	0,08	0,35	disease	0,52	disease	0,73	neutral	0,5	neutral	0,26	5	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,23	medium_impact	1,03	medium_impact	0,15	medium_impact	-0,47	0,14	0,8	0,58	8,19	N	0,27	N	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4760	4760	A	C	MI.13372	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	291	97	M	I	atA/atC	3,02	0,14	0	benign	0,01	neutral	0,76	neutral	4,65	neutral	-0,46	neutral	-0,54	neutral_impact	-0,32	neutral	0,92	neutral	0,97	deleterious	0,74	9,11	0,23	0,45	disease	0,59	disease	0,52	neutral	0,42	neutral	0,32	4	neutral	0,22	deleterious	0,88	neutral	-6	neutral	0,2	medium_impact	1,03	medium_impact	0,49	low_impact	-1,41	0,38	0,8	0,58	8,19	N	0,28	N	0,82	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4760	4760	A	T	MI.13373	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	291	97	M	I	atA/atT	3,02	0,14	0	benign	0,01	neutral	0,76	neutral	4,65	neutral	-0,46	neutral	-0,54	neutral_impact	-0,32	neutral	0,92	neutral	0,97	deleterious	0,8	9,47	0,23	0,45	disease	0,59	disease	0,52	neutral	0,42	neutral	0,32	4	neutral	0,22	deleterious	0,88	neutral	-6	neutral	0,2	medium_impact	1,03	medium_impact	0,49	low_impact	-1,41	0,38	0,8	0,58	8,19	N	0,28	N	0,82	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4761	4761	A	C	MI.13374	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	292	98	I	L	Atc/Ctc	-4,35	0	0	benign	0,01	neutral	1	neutral	4,86	neutral	0,81	neutral	0,21	neutral_impact	-0,18	neutral	0,82	neutral	0,93	deleterious	0,16	4,3	0,19	0,45	neutral	0,36	neutral	0,28	neutral	0,26	neutral	0,45	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,03	high_impact	1,87	low_impact	-1,3	0,47	0,8	6,92	7,93	N	0,25	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4761	4761	A	T	MI.13375	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	292	98	I	F	Atc/Ttc	-4,35	0	0	benign	0,21	neutral	0,66	neutral	4,45	neutral	-1,32	neutral	-1,69	low_impact	1,17	neutral	0,91	neutral	0,87	deleterious	1,88	15,47	0,12	0,4	disease	0,51	disease	0,67	neutral	0,4	neutral	0,22	6	neutral	0,22	deleterious	0,73	neutral	-6	deleterious	0,48	medium_impact	-0,27	medium_impact	0,37	medium_impact	-0,16	0,48	0,8	6,92	7,93	N	0,25	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4761	4761	A	G	MI.13376	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	292	98	I	V	Atc/Gtc	-4,35	0	0	benign	0,01	neutral	0,51	neutral	4,45	neutral	-1,29	neutral	-0,24	low_impact	1,32	neutral	0,92	neutral	0,97	neutral	-0,1	1,7	0,25	0,45	disease	0,6	neutral	0,4	neutral	0,38	disease	0,61	2	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,18	medium_impact	1,03	medium_impact	0,22	medium_impact	-0,03	0,42	0,8	6,92	7,93	N	0,35	N	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4762	4762	T	G	MI.13377	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	293	98	I	S	aTc/aGc	-0,43	0	0	benign	0,14	neutral	0,54	neutral	4,35	deleterious	-3,02	deleterious	-2,64	medium_impact	2,4	neutral	0,87	neutral	0,51	deleterious	2,49	19,39	0,03	0,35	disease	0,76	disease	0,74	disease	0,59	disease	0,71	4	neutral	0,36	deleterious	0,7	neutral	-3	neutral	0,38	medium_impact	-0,08	medium_impact	0,25	medium_impact	0,88	0,35	0,8	6,92	7,93	N	0,23	N	0,47	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4762	4762	T	C	MI.13378	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	293	98	I	T	aTc/aCc	-0,43	0	0	benign	0,01	neutral	0,41	neutral	4,34	deleterious	-3,27	neutral	-2,17	low_impact	1,38	neutral	0,91	neutral	0,97	deleterious	0,2	4,69	0,06	0,35	disease	0,64	disease	0,56	neutral	0,4	neutral	0,23	5	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,22	medium_impact	1,03	medium_impact	0,12	medium_impact	0,02	0,26	0,8	6,92	7,93	N	0,35	N	0,28	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4762	4762	T	A	MI.13379	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	293	98	I	N	aTc/aAc	-0,43	0	0	possibly_damaging	0,46	neutral	0,31	neutral	4,31	deleterious	-4,95	deleterious	-3,75	medium_impact	2,94	neutral	0,88	neutral	0,43	deleterious	4,16	23,8	0,06	0,35	disease	0,91	disease	0,76	disease	0,6	disease	0,71	4	neutral	0,65	neutral	0,43	NA	0	deleterious	0,61	medium_impact	-0,73	medium_impact	0,02	medium_impact	1,33	0,37	0,8	6,92	7,93	N	0,41	N	0,69	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9154	9154	C	G	MI.1338	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	628	210	Q	E	Caa/Gaa	-2,88	0	0	probably_damaging	0,94	deleterious	0	neutral	2,99	deleterious	-6,46	deleterious	-2,65	high_impact	4,59	neutral	0,68	damaging	0,16	deleterious	3,19	22,7	0,2	0,65	NA	NA	disease	0,88	disease	0,77	disease	0,77	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,89	low_impact	-1,89	low_impact	-1,4	high_impact	2,84	0,55	0,9	49,56	8,86	N	0,52	P	0,94	disease_causing	0,85	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4763	4763	C	A	MI.13380	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	294	98	I	M	atC/atA	0,72	0	0	benign	0,01	neutral	0,35	neutral	4,42	neutral	-1,71	neutral	1,23	neutral_impact	-0,09	neutral	0,91	neutral	0,93	neutral	-0,89	0,03	0,17	0,45	disease	0,5	neutral	0,33	neutral	0,29	neutral	0,15	7	neutral	0,64	deleterious	0,67	neutral	-6	neutral	0,17	medium_impact	1,03	medium_impact	0,06	low_impact	-1,22	0,38	0,8	6,92	7,93	N	0,36	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4763	4763	C	G	MI.13381	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	294	98	I	M	atC/atG	0,72	0	0	benign	0,01	neutral	0,35	neutral	4,42	neutral	-1,71	neutral	1,23	neutral_impact	-0,09	neutral	0,91	neutral	0,93	neutral	-1,39	0	0,17	0,45	disease	0,5	neutral	0,33	neutral	0,29	neutral	0,15	7	neutral	0,64	deleterious	0,67	neutral	-6	neutral	0,17	medium_impact	1,03	medium_impact	0,06	low_impact	-1,22	0,38	0,8	6,92	7,93	N	0,36	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4764	4764	A	G	MI.13382	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	295	99	M	V	Ata/Gta	-5,73	0	0	benign	0	neutral	0,51	neutral	4,76	neutral	0,88	neutral	0,18	neutral_impact	0,32	neutral	0,93	neutral	0,77	neutral	-0,36	0,49	0,21	0,45	neutral	0,41	disease	0,78	neutral	0,48	neutral	0,39	2	neutral	0,49	deleterious	0,76	neutral	-6	neutral	0,22	medium_impact	1,95	medium_impact	0,22	medium_impact	-0,88	0,46	0,8	0,58	7,94	N	0,24	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4764	4764	A	C	MI.13383	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	295	99	M	L	Ata/Cta	-5,73	0	0	benign	0	neutral	0,75	neutral	4,88	neutral	2,73	neutral	-0,05	neutral_impact	-0,3	neutral	0,94	neutral	0,96	neutral	-0,2	1,08	0,22	0,45	neutral	0,36	disease	0,71	neutral	0,46	neutral	0,17	7	neutral	0,25	deleterious	0,88	neutral	-6	neutral	0,21	medium_impact	1,95	medium_impact	0,47	low_impact	-1,4	0,39	0,8	0,58	7,94	N	0,27	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4764	4764	A	T	MI.13384	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	295	99	M	L	Ata/Tta	-5,73	0	0	benign	0	neutral	0,75	neutral	4,88	neutral	2,73	neutral	-0,05	neutral_impact	-0,3	neutral	0,94	neutral	0,96	neutral	-0,13	1,5	0,22	0,45	neutral	0,36	disease	0,71	neutral	0,46	neutral	0,17	7	neutral	0,25	deleterious	0,88	neutral	-6	neutral	0,21	medium_impact	1,95	medium_impact	0,47	low_impact	-1,4	0,39	0,8	0,58	7,94	N	0,28	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4765	4765	T	A	MI.13385	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	296	99	M	K	aTa/aAa	1,18	0	0	benign	0,04	neutral	0,35	neutral	4,59	neutral	-2,53	neutral	-1,36	medium_impact	1,96	neutral	0,85	neutral	0,47	deleterious	1,91	15,66	0,03	0,35	disease	0,82	disease	0,88	disease	0,7	disease	0,7	4	neutral	0,62	deleterious	0,66	neutral	-3	neutral	0,33	medium_impact	0,47	medium_impact	0,06	medium_impact	0,51	0,29	0,8	0,58	7,94	N	0,28	N	0,55	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4765	4765	T	C	MI.13386	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	296	99	M	T	aTa/aCa	1,18	0	0	benign	0	neutral	0,55	neutral	4,7	neutral	-0,14	neutral	2,88	neutral_impact	-1,7	neutral	0,88	neutral	0,93	neutral	-1,8	0	0,11	0,4	neutral	0,4	neutral	0,34	neutral	0,39	neutral	0,41	2	neutral	0,45	deleterious	0,78	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,26	low_impact	-2,58	0,16	0,8	0,58	7,94	N	0,26	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4766	4766	A	T	MI.13387	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	297	99	M	I	atA/atT	0,95	0	0	benign	0	neutral	0,47	neutral	4,78	neutral	0,87	neutral	-0,35	neutral_impact	-0,41	neutral	0,88	neutral	0,78	deleterious	0,33	5,98	0,26	0,45	disease	0,53	disease	0,79	neutral	0,46	neutral	0,2	6	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,27	medium_impact	1,95	medium_impact	0,18	low_impact	-1,49	0,44	0,8	0,58	7,94	N	0,26	N	0,17	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4766	4766	A	C	MI.13388	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	297	99	M	I	atA/atC	0,95	0	0	benign	0	neutral	0,47	neutral	4,78	neutral	0,87	neutral	-0,35	neutral_impact	-0,41	neutral	0,88	neutral	0,78	deleterious	0,27	5,44	0,26	0,45	disease	0,53	disease	0,79	neutral	0,46	neutral	0,2	6	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,27	medium_impact	1,95	medium_impact	0,18	low_impact	-1,49	0,44	0,8	0,58	7,94	N	0,25	N	0,17	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4767	4767	A	C	MI.13389	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	298	100	M	L	Ata/Cta	-10,1	0	0,01	benign	0	neutral	1	neutral	4,82	neutral	1,97	neutral	0,07	neutral_impact	-0,25	neutral	0,84	neutral	0,99	neutral	-1,24	0,01	0,25	0,45	disease	0,59	disease	0,65	neutral	0,4	neutral	0,31	4	neutral	0	deleterious	1	neutral	-6	neutral	0,17	medium_impact	1,95	high_impact	1,87	low_impact	-1,36	0,47	0,8	0,58	8,47	N	0,31	N	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9155	9155	A	C	MI.1339	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	629	210	Q	P	cAa/cCa	7,3	1	0	probably_damaging	0,98	deleterious	0	neutral	2,92	deleterious	-8,64	deleterious	-5,34	high_impact	4,24	damaging	0,53	damaging	0,15	deleterious	3,49	23,1	0,14	0,65	NA	NA	disease	0,93	disease	0,82	disease	0,86	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,94	low_impact	-2,36	low_impact	-1,4	high_impact	2,54	0,49	0,9	49,56	8,86	N	0,46	N	0,98	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4767	4767	A	G	MI.13390	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	298	100	M	V	Ata/Gta	-10,1	0	0,01	benign	0	neutral	0,33	neutral	4,84	neutral	2,33	neutral	-0,18	low_impact	0,98	neutral	0,94	neutral	0,96	neutral	-0,56	0,15	0,21	0,45	neutral	0,37	disease	0,72	neutral	0,45	neutral	0,24	5	neutral	0,67	deleterious	0,67	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	0,04	medium_impact	-0,32	0,48	0,8	0,58	8,47	N	0,32	N	0,32	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4767	4767	A	T	MI.13391	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	298	100	M	L	Ata/Tta	-10,1	0	0,01	benign	0	neutral	1	neutral	4,82	neutral	1,97	neutral	0,07	neutral_impact	-0,25	neutral	0,84	neutral	0,99	neutral	-1,17	0,01	0,25	0,45	disease	0,59	disease	0,65	neutral	0,4	neutral	0,31	4	neutral	0	deleterious	1	neutral	-6	neutral	0,17	medium_impact	1,95	high_impact	1,87	low_impact	-1,36	0,47	0,8	0,58	8,47	N	0,31	N	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4768	4768	T	C	MI.13392	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	299	100	M	T	aTa/aCa	-4,58	0	0	benign	0	neutral	0,36	neutral	4,61	neutral	-0,25	neutral	-2,01	neutral_impact	0,66	neutral	0,94	neutral	0,99	neutral	-0,46	0,27	0,09	0,35	neutral	0,45	disease	0,59	neutral	0,44	neutral	0,24	5	neutral	0,64	deleterious	0,68	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	0,07	medium_impact	-0,59	0,19	0,8	0,58	8,47	N	0,31	N	0,03	polymorphism	1	0,04	rs878853032	Uncertain significance	not_provided	RCV000224931.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	4768	4768	T	A	MI.13393	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	299	100	M	K	aTa/aAa	-4,58	0	0	benign	0,04	neutral	0,23	neutral	4,54	neutral	-2,11	deleterious	-3,68	medium_impact	2,73	neutral	0,87	neutral	0,38	deleterious	2,21	17,55	0,03	0,35	disease	0,77	disease	0,89	disease	0,7	disease	0,77	5	neutral	0,75	deleterious	0,6	neutral	-3	neutral	0,28	medium_impact	0,47	medium_impact	-0,08	medium_impact	1,15	0,3	0,8	0,58	8,47	N	0,35	N	0,62	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4769	4769	A	T	MI.13394	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	300	100	M	I	atA/atT	-0,66	0	0,27	benign	0	neutral	0,56	neutral	4,74	neutral	2,14	neutral	0,2	neutral_impact	-0,24	neutral	0,9	neutral	0,98	neutral	-1,22	0,01	0,2	0,45	neutral	0,37	disease	0,64	neutral	0,35	neutral	0,29	4	neutral	0,44	deleterious	0,78	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	0,27	low_impact	-1,35	0,5	0,8	0,58	8,47	N	0,31	N	0,12	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4769	4769	A	C	MI.13395	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	300	100	M	I	atA/atC	-0,66	0	0,27	benign	0	neutral	0,56	neutral	4,74	neutral	2,14	neutral	0,2	neutral_impact	-0,24	neutral	0,9	neutral	0,98	neutral	-1,39	0	0,2	0,45	neutral	0,37	disease	0,64	neutral	0,35	neutral	0,29	4	neutral	0,44	deleterious	0,78	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	0,27	low_impact	-1,35	0,5	0,8	0,58	8,47	N	0,31	N	0,12	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4770	4770	G	T	MI.13396	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	301	101	A	S	Gct/Tct	-20	0	0	probably_damaging	1	neutral	0,45	neutral	4,33	neutral	-2,39	neutral	-2,37	low_impact	1,18	neutral	0,89	neutral	0,78	deleterious	2,27	17,99	0,15	0,4	disease	0,64	disease	0,75	neutral	0,41	neutral	0,2	6	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,79	low_impact	-3,54	medium_impact	0,16	medium_impact	-0,15	0,38	0,8	0,29	6,81	N	0,33	N	0,21	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4770	4770	G	A	MI.13397	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	301	101	A	T	Gct/Act	-20	0	0	probably_damaging	1	neutral	0,41	neutral	4,24	deleterious	-3,12	deleterious	-3,51	medium_impact	2,48	neutral	0,93	damaging	0,15	deleterious	4,05	23,7	0,06	0,35	disease	0,62	disease	0,83	disease	0,58	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	0,12	medium_impact	0,94	0,65	0,8	0,29	6,81	N	0,34	N	0,71	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4770	4770	G	C	MI.13398	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	301	101	A	P	Gct/Cct	-20	0	0	probably_damaging	1	neutral	0,24	neutral	4,18	deleterious	-5,21	deleterious	-4,57	medium_impact	3,2	neutral	0,9	damaging	0,15	deleterious	3,66	23,2	0,03	0,35	disease	0,92	disease	0,86	disease	0,75	disease	0,61	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	-0,07	medium_impact	1,55	0,3	0,8	0,29	6,81	N	0,4	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4771	4771	C	T	MI.13399	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	302	101	A	V	gCt/gTt	3,48	1	0	probably_damaging	1	neutral	0,55	neutral	4,21	neutral	-2,78	deleterious	-3,78	high_impact	3,54	neutral	0,84	damaging	0,12	deleterious	4,24	23,9	0,05	0,35	disease	0,66	disease	0,86	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,26	medium_impact	1,84	0,52	0,8	0,29	6,81	N	0,43	N	0,8	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8588	8588	T	G	MI.134	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	62	21	V	G	gTa/gGa	-2,42	0	0	possibly_damaging	0,83	neutral	0,12	neutral	4,23	neutral	-2,96	deleterious	-3,43	neutral_impact	0,22	neutral	0,84	neutral	0,73	deleterious	2,28	18,03	0,23	0,65	neutral	0,48	neutral	0,32	neutral	0,46	neutral	0,42	2	neutral	0,93	neutral	0,15	neutral	-3	deleterious	0,63	low_impact	-1,41	medium_impact	-0,2	medium_impact	-0,91	0,5	0,9	22,57	20,88	N	0,4	N	0,84	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9155	9155	A	G	MI.1340	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	629	210	Q	R	cAa/cGa	7,3	1	0	probably_damaging	0,97	deleterious	0	neutral	2,95	deleterious	-6,4	deleterious	-3,54	high_impact	4,59	damaging	0,59	damaging	0,14	deleterious	3,54	23,1	0,21	0,65	NA	NA	disease	0,93	disease	0,81	disease	0,84	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,92	low_impact	-2,19	low_impact	-1,4	high_impact	2,84	0,48	0,9	49,56	8,86	P	0,53	P	0,91	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4771	4771	C	A	MI.13400	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	302	101	A	D	gCt/gAt	3,48	1	0	probably_damaging	1	neutral	0,21	neutral	4,18	deleterious	-5,27	deleterious	-5,36	high_impact	3,54	neutral	0,88	damaging	0,12	deleterious	4,43	24,2	0,02	0,35	disease	0,95	disease	0,91	disease	0,74	disease	0,61	2	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	-0,11	medium_impact	1,84	0,25	0,8	0,29	6,81	N	0,54	P	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4771	4771	C	G	MI.13401	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	302	101	A	G	gCt/gGt	3,48	1	0	probably_damaging	1	neutral	0,4	neutral	4,53	neutral	1,76	deleterious	-3,6	medium_impact	1,97	neutral	0,87	damaging	0,15	deleterious	3,79	23,4	0,11	0,4	neutral	0,45	disease	0,76	neutral	0,49	neutral	0,4	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,11	medium_impact	0,51	0,58	0,8	0,29	6,81	N	0,44	N	0,51	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4773	4773	A	G	MI.13402	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	304	102	M	V	Ata/Gta	-10,33	0	0	benign	0,02	neutral	0,25	neutral	4,74	neutral	1,08	neutral	-1,31	low_impact	1,04	neutral	0,89	neutral	0,69	deleterious	0,82	9,58	0,16	0,45	neutral	0,43	disease	0,77	disease	0,59	neutral	0,47	1	neutral	0,74	deleterious	0,62	neutral	-6	neutral	0,23	medium_impact	0,75	medium_impact	-0,06	medium_impact	-0,27	0,29	0,8	0,58	6,92	N	0,31	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4773	4773	A	T	MI.13403	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	304	102	M	L	Ata/Tta	-10,33	0	0	benign	0	neutral	1	neutral	4,98	neutral	2,46	neutral	1,15	neutral_impact	-1,51	neutral	0,9	neutral	0,96	neutral	-1,23	0,01	0,2	0,45	disease	0,54	neutral	0,43	neutral	0,33	disease	0,55	1	neutral	0	deleterious	1	neutral	-6	neutral	0,17	medium_impact	1,95	high_impact	1,87	low_impact	-2,42	0,27	0,8	0,58	6,92	N	0,29	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4773	4773	A	C	MI.13404	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	304	102	M	L	Ata/Cta	-10,33	0	0	benign	0	neutral	1	neutral	4,98	neutral	2,46	neutral	1,15	neutral_impact	-1,51	neutral	0,9	neutral	0,96	neutral	-1,38	0	0,2	0,45	disease	0,54	neutral	0,43	neutral	0,33	disease	0,55	1	neutral	0	deleterious	1	neutral	-6	neutral	0,17	medium_impact	1,95	high_impact	1,87	low_impact	-2,42	0,27	0,8	0,58	6,92	N	0,29	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4774	4774	T	A	MI.13405	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	305	102	M	K	aTa/aAa	-0,43	0	0	benign	0,2	neutral	0,1	neutral	4,63	neutral	-1,97	deleterious	-4,16	medium_impact	2,37	neutral	0,83	neutral	0,47	deleterious	2,03	16,39	0,03	0,35	disease	0,75	disease	0,87	disease	0,67	disease	0,76	5	neutral	0,88	neutral	0,45	neutral	-3	deleterious	0,53	medium_impact	-0,25	medium_impact	-0,32	medium_impact	0,85	0,16	0,8	0,58	6,92	N	0,32	N	0,59	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4774	4774	T	C	MI.13406	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	305	102	M	T	aTa/aCa	-0,43	0	0	benign	0,1	neutral	0,11	neutral	4,66	neutral	-0,55	deleterious	-3,31	medium_impact	2,02	neutral	0,84	neutral	0,61	neutral	0,99	10,61	0,06	0,35	neutral	0,49	disease	0,7	disease	0,59	disease	0,67	3	neutral	0,88	deleterious	0,51	neutral	-3	neutral	0,31	medium_impact	0,08	medium_impact	-0,3	medium_impact	0,56	0,13	0,8	0,58	6,92	N	0,34	N	0,5	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4775	4775	A	T	MI.13407	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	306	102	M	I	atA/atT	5,78	0,87	0	benign	0,01	neutral	0,26	neutral	4,69	neutral	1,2	neutral	-0,5	neutral_impact	-0,04	neutral	0,82	neutral	0,69	neutral	1,48	13,2	0,2	0,45	neutral	0,35	disease	0,57	neutral	0,38	neutral	0,22	6	neutral	0,73	deleterious	0,63	neutral	-6	neutral	0,21	medium_impact	1,03	medium_impact	-0,04	low_impact	-1,18	0,34	0,8	0,58	6,92	N	0,44	N	0,1	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4775	4775	A	C	MI.13408	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	306	102	M	I	atA/atC	5,78	0,87	0	benign	0,01	neutral	0,26	neutral	4,69	neutral	1,2	neutral	-0,5	neutral_impact	-0,04	neutral	0,82	neutral	0,69	neutral	1,39	12,71	0,2	0,45	neutral	0,35	disease	0,57	neutral	0,38	neutral	0,22	6	neutral	0,73	deleterious	0,63	neutral	-6	neutral	0,21	medium_impact	1,03	medium_impact	-0,04	low_impact	-1,18	0,34	0,8	0,58	6,92	N	0,43	N	0,1	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4776	4776	G	A	MI.13409	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	307	103	A	T	Gca/Aca	-6,19	0	0	benign	0,02	neutral	0,4	neutral	4,52	deleterious	-3,01	neutral	-0,44	low_impact	1,53	neutral	0,9	neutral	0,93	deleterious	0,58	7,98	0,17	0,45	disease	0,66	disease	0,75	neutral	0,36	neutral	0,21	6	neutral	0,58	deleterious	0,69	neutral	-6	neutral	0,26	medium_impact	0,75	medium_impact	0,11	medium_impact	0,14	0,7	0,85	4,03	8,64	N	0,32	N	0,48	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9155	9155	A	T	MI.1341	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	629	210	Q	L	cAa/cTa	7,3	1	0	probably_damaging	0,97	deleterious	0	neutral	2,92	deleterious	-7,61	deleterious	-6,19	high_impact	4,59	neutral	0,63	damaging	0,13	deleterious	3,94	23,5	0,15	0,65	NA	NA	disease	0,95	disease	0,74	disease	0,85	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,9	low_impact	-2,19	low_impact	-1,4	high_impact	2,84	0,35	0,9	49,56	8,86	N	0,47	N	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4776	4776	G	C	MI.13410	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	307	103	A	P	Gca/Cca	-6,19	0	0	possibly_damaging	0,85	neutral	0,21	neutral	4,47	deleterious	-5,47	deleterious	-2,77	medium_impact	3,37	neutral	0,81	neutral	0,31	deleterious	3,57	23,1	0,04	0,35	disease	0,9	disease	0,9	disease	0,7	disease	0,63	3	neutral	0,91	neutral	0,18	NA	0	deleterious	0,82	low_impact	-1,49	medium_impact	-0,11	medium_impact	1,69	0,56	0,8	4,03	8,64	N	0,38	N	0,9	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4776	4776	G	T	MI.13411	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	307	103	A	S	Gca/Tca	-6,19	0	0	benign	0,33	neutral	0,45	neutral	4,51	deleterious	-3,1	neutral	-0,98	low_impact	1,15	neutral	0,76	neutral	0,92	deleterious	0,59	8,07	0,25	0,45	disease	0,6	disease	0,67	neutral	0,35	neutral	0,21	6	neutral	0,47	deleterious	0,56	neutral	-6	deleterious	0,5	medium_impact	-0,52	medium_impact	0,16	medium_impact	-0,18	0,4	0,8	4,03	8,64	N	0,31	N	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4777	4777	C	G	MI.13412	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	308	103	A	G	gCa/gGa	-2,96	0	0	possibly_damaging	0,53	neutral	0,38	neutral	4,54	neutral	-0,69	deleterious	-2,78	medium_impact	2,12	neutral	0,89	neutral	0,78	neutral	0,93	10,27	0,2	0,45	disease	0,81	disease	0,79	neutral	0,45	neutral	0,46	1	neutral	0,61	neutral	0,43	NA	0	deleterious	0,66	medium_impact	-0,84	medium_impact	0,09	medium_impact	0,64	0,64	0,8	4,03	8,64	N	0,37	N	0,48	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4777	4777	C	T	MI.13413	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	308	103	A	V	gCa/gTa	-2,96	0	0	benign	0,04	neutral	0,54	neutral	4,6	neutral	-2,19	neutral	-0,81	low_impact	1,57	neutral	0,9	neutral	0,88	neutral	1,43	12,93	0,13	0,4	neutral	0,38	disease	0,86	disease	0,57	neutral	0,4	2	neutral	0,41	deleterious	0,75	neutral	-6	neutral	0,25	medium_impact	0,47	medium_impact	0,25	medium_impact	0,18	0,58	0,8	4,03	8,64	N	0,25	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4777	4777	C	A	MI.13414	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	308	103	A	E	gCa/gAa	-2,96	0	0	possibly_damaging	0,66	neutral	0,27	neutral	4,47	deleterious	-5,14	deleterious	-2,69	medium_impact	3,02	neutral	0,89	neutral	0,41	deleterious	4,08	23,7	0,04	0,35	disease	0,88	disease	0,89	disease	0,68	disease	0,64	3	neutral	0,77	neutral	0,31	NA	0	deleterious	0,73	low_impact	-1,06	medium_impact	-0,03	medium_impact	1,4	0,33	0,8	4,03	8,64	N	0,4	N	0,88	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4779	4779	A	T	MI.13415	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	310	104	M	L	Ata/Tta	-6,65	0	0	benign	0,01	neutral	1	neutral	4,8	neutral	1,03	deleterious	-2,71	low_impact	1,1	neutral	0,84	neutral	0,54	deleterious	2,1	16,88	0,3	0,45	disease	0,54	disease	0,68	neutral	0,47	neutral	0,19	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,2	medium_impact	1,03	high_impact	1,87	medium_impact	-0,22	0,41	0,8	NA	NA	N	0,17	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4779	4779	A	C	MI.13416	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	310	104	M	L	Ata/Cta	-6,65	0	0	benign	0,01	neutral	1	neutral	4,8	neutral	1,03	deleterious	-2,71	low_impact	1,1	neutral	0,84	neutral	0,54	deleterious	1,95	15,91	0,3	0,45	disease	0,54	disease	0,68	neutral	0,47	neutral	0,19	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,2	medium_impact	1,03	high_impact	1,87	medium_impact	-0,22	0,41	0,8	NA	NA	N	0,17	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4779	4779	A	G	MI.13417	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	310	104	M	V	Ata/Gta	-6,65	0	0	benign	0,27	neutral	0,33	neutral	4,85	neutral	1,92	deleterious	-3,6	medium_impact	2,26	neutral	0,94	neutral	0,59	deleterious	2,59	20,2	0,31	0,45	neutral	0,48	disease	0,87	disease	0,61	disease	0,68	4	neutral	0,6	deleterious	0,53	neutral	-3	deleterious	0,51	medium_impact	-0,4	medium_impact	0,04	medium_impact	0,76	0,38	0,8	NA	NA	N	0,33	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4780	4780	T	C	MI.13418	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	311	104	M	T	aTa/aCa	3,94	0,99	0	benign	0,03	neutral	0,29	neutral	4,71	neutral	1,44	deleterious	-5,61	medium_impact	1,97	neutral	0,93	neutral	0,69	deleterious	2,82	21,5	0,09	0,35	disease	0,65	disease	0,85	disease	0,61	disease	0,54	1	neutral	0,69	deleterious	0,63	neutral	-3	neutral	0,33	medium_impact	0,59	medium_impact	-0,01	medium_impact	0,51	0,16	0,8	NA	NA	N	0,48	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4780	4780	T	A	MI.13419	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	311	104	M	K	aTa/aAa	3,94	0,99	0	possibly_damaging	0,53	neutral	0,36	neutral	4,6	neutral	-1,75	deleterious	-5,7	medium_impact	3,42	neutral	0,82	neutral	0,41	deleterious	3,93	23,5	0,03	0,35	disease	0,86	disease	0,93	disease	0,73	disease	0,67	3	neutral	0,63	neutral	0,42	NA	0	deleterious	0,72	medium_impact	-0,84	medium_impact	0,07	medium_impact	1,73	0,17	0,8	NA	NA	P	0,59	P	0,98	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9156	9156	A	C	MI.1342	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	630	210	Q	H	caA/caC	8,69	1	0	probably_damaging	1	deleterious	0,03	neutral	2,92	deleterious	-8,14	deleterious	-4,42	high_impact	4,24	neutral	0,63	damaging	0,13	deleterious	3,59	23,2	0,24	0,65	NA	NA	disease	0,89	disease	0,82	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,92	low_impact	-3,6	medium_impact	-0,56	high_impact	2,54	0,55	0,9	49,56	8,86	N	0,47	N	0,97	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4781	4781	A	T	MI.13420	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	312	104	M	I	atA/atT	5,78	1	0	benign	0,27	neutral	0,47	neutral	4,8	neutral	1,83	deleterious	-3,56	low_impact	1,54	neutral	0,9	neutral	0,94	deleterious	1,98	16,08	0,26	0,45	neutral	0,4	disease	0,82	neutral	0,48	neutral	0,16	7	neutral	0,43	deleterious	0,6	neutral	-6	deleterious	0,49	medium_impact	-0,4	medium_impact	0,18	medium_impact	0,15	0,33	0,8	NA	NA	P	0,58	P	0,93	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4781	4781	A	C	MI.13421	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	312	104	M	I	atA/atC	5,78	1	0	benign	0,27	neutral	0,47	neutral	4,8	neutral	1,83	deleterious	-3,56	low_impact	1,54	neutral	0,9	neutral	0,94	deleterious	1,9	15,59	0,26	0,45	neutral	0,4	disease	0,82	neutral	0,48	neutral	0,16	7	neutral	0,43	deleterious	0,6	neutral	-6	deleterious	0,49	medium_impact	-0,4	medium_impact	0,18	medium_impact	0,15	0,33	0,8	NA	NA	P	0,58	P	0,93	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4782	4782	A	G	MI.13422	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	313	105	K	E	Aaa/Gaa	-1,12	0	0	probably_damaging	1	neutral	0,27	neutral	3,17	deleterious	-7,64	deleterious	-3,87	high_impact	4,15	neutral	0,72	damaging	0,07	deleterious	3,92	23,5	0,06	0,35	disease	0,85	disease	0,77	disease	0,79	disease	0,68	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,03	high_impact	2,35	0,3	0,8	NA	NA	N	0,44	N	0,91	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4782	4782	A	C	MI.13423	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	313	105	K	Q	Aaa/Caa	-1,12	0	0	probably_damaging	1	neutral	0,29	neutral	3,17	deleterious	-7,91	deleterious	-3,87	high_impact	4,15	neutral	0,67	damaging	0,06	deleterious	3,34	22,9	0,09	0,35	disease	0,85	disease	0,71	disease	0,77	disease	0,68	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	-0,01	high_impact	2,35	0,36	0,8	NA	NA	N	0,44	N	0,88	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4783	4783	A	C	MI.13424	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	314	105	K	T	aAa/aCa	8,55	1	0	probably_damaging	1	neutral	0,39	neutral	3,15	deleterious	-9,09	deleterious	-5,8	high_impact	4,15	neutral	0,73	damaging	0,1	deleterious	3,47	23	0,06	0,35	disease	0,61	disease	0,77	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	0,1	high_impact	2,35	0,2	0,8	NA	NA	P	0,64	P	0,81	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4783	4783	A	T	MI.13425	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	314	105	K	M	aAa/aTa	8,55	1	0	probably_damaging	1	neutral	0,24	neutral	3,13	deleterious	-10,66	deleterious	-5,8	high_impact	4,15	neutral	0,7	damaging	0,04	deleterious	3,7	23,3	0,05	0,35	disease	0,59	disease	0,78	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,75	low_impact	-3,54	medium_impact	-0,07	high_impact	2,35	0,17	0,8	NA	NA	P	0,61	P	0,45	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4784	4784	A	T	MI.13426	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	315	105	K	N	aaA/aaT	8,55	1	0	probably_damaging	1	neutral	0,31	neutral	3,18	deleterious	-8,51	deleterious	-4,84	high_impact	3,8	neutral	0,66	damaging	0,04	deleterious	3,72	23,3	0,09	0,35	disease	0,75	disease	0,71	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	0,02	high_impact	2,05	0,2	0,8	NA	NA	P	0,63	P	0,69	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4784	4784	A	C	MI.13427	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	315	105	K	N	aaA/aaC	8,55	1	0	probably_damaging	1	neutral	0,31	neutral	3,18	deleterious	-8,51	deleterious	-4,84	high_impact	3,8	neutral	0,66	damaging	0,04	deleterious	3,67	23,3	0,09	0,35	disease	0,75	disease	0,71	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	0,02	high_impact	2,05	0,2	0,8	NA	NA	P	0,63	P	0,69	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4785	4785	C	A	MI.13428	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	316	106	L	M	Cta/Ata	4,63	1	0	possibly_damaging	0,71	neutral	0,29	neutral	4,45	neutral	-1,58	neutral	-1,44	low_impact	1,5	neutral	0,94	damaging	0,19	deleterious	3,73	23,3	0,39	0,5	disease	0,77	disease	0,7	neutral	0,36	neutral	0,22	6	neutral	0,78	neutral	0,29	neutral	-3	deleterious	0,71	low_impact	-1,15	medium_impact	-0,01	medium_impact	0,12	0,63	0,8	0,29	7,5	N	0,55	P	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4785	4785	C	G	MI.13429	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	316	106	L	V	Cta/Gta	4,63	1	0	possibly_damaging	0,87	neutral	0,54	neutral	4,48	neutral	-0,21	deleterious	-2,7	medium_impact	2,37	neutral	0,86	damaging	0,16	deleterious	3,25	22,8	0,28	0,45	disease	0,67	disease	0,77	disease	0,52	neutral	0,2	6	neutral	0,85	neutral	0,34	NA	0	deleterious	0,76	low_impact	-1,55	medium_impact	0,25	medium_impact	0,85	0,54	0,8	0,29	7,5	N	0,48	N	0,77	polymorphism	1	0,05	rs28613328	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9156	9156	A	T	MI.1343	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	630	210	Q	H	caA/caT	8,69	1	0	probably_damaging	1	deleterious	0,03	neutral	2,92	deleterious	-8,14	deleterious	-4,42	high_impact	4,24	neutral	0,63	damaging	0,13	deleterious	3,73	23,3	0,24	0,65	NA	NA	disease	0,89	disease	0,82	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,92	low_impact	-3,6	medium_impact	-0,56	high_impact	2,54	0,55	0,9	49,56	8,86	N	0,49	N	0,97	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4786	4786	T	C	MI.13430	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	317	106	L	P	cTa/cCa	-0,66	0,22	0	probably_damaging	0,99	neutral	0,28	neutral	4,37	deleterious	-4,65	deleterious	-6,47	high_impact	3,56	neutral	0,84	damaging	0,08	deleterious	3,88	23,5	0,03	0,35	disease	0,97	disease	0,87	disease	0,76	disease	0,65	3	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,87	low_impact	-2,62	medium_impact	-0,02	medium_impact	1,85	0,25	0,8	0,29	7,5	N	0,37	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4786	4786	T	A	MI.13431	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	317	106	L	Q	cTa/cAa	-0,66	0,22	0	probably_damaging	0,99	neutral	0,26	neutral	4,38	deleterious	-4,32	deleterious	-5,41	high_impact	3,91	neutral	0,85	damaging	0,11	deleterious	4,29	24	0,04	0,35	disease	0,96	disease	0,84	disease	0,65	disease	0,67	3	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-2,62	medium_impact	-0,04	high_impact	2,15	0,24	0,8	0,29	7,5	N	0,33	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4786	4786	T	G	MI.13432	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	317	106	L	R	cTa/cGa	-0,66	0,22	0	probably_damaging	0,99	neutral	0,31	neutral	4,38	deleterious	-4,17	deleterious	-5,51	high_impact	3,91	neutral	0,81	damaging	0,08	deleterious	4,13	23,8	0,03	0,35	disease	0,95	disease	0,94	disease	0,76	disease	0,64	3	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,91	low_impact	-2,62	medium_impact	0,02	high_impact	2,15	0,17	0,8	0,29	7,5	N	0,38	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4788	4788	G	T	MI.13433	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	319	107	G	W	Gga/Tga	-1,12	0,01	0	probably_damaging	1	neutral	0,19	neutral	4,3	deleterious	-8,97	deleterious	-7,74	high_impact	4,12	damaging	0,57	damaging	0,02	deleterious	4,29	24	0,04	0,35	neutral	0,42	disease	0,89	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	-0,14	high_impact	2,32	0,08	0,8	NA	NA	N	0,35	N	0,99	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4788	4788	G	C	MI.13434	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	319	107	G	R	Gga/Cga	-1,12	0,01	0	probably_damaging	1	neutral	0,36	neutral	4,31	deleterious	-5,91	deleterious	-7,73	high_impact	4,12	damaging	0,5	damaging	0,02	deleterious	3,78	23,4	0,03	0,35	disease	0,84	disease	0,92	disease	0,77	disease	0,66	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	0,07	high_impact	2,32	0,56	0,8	NA	NA	N	0,41	N	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4789	4789	G	T	MI.13435	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	320	107	G	V	gGa/gTa	6,01	1	0	probably_damaging	1	neutral	0,54	neutral	4,32	deleterious	-4,98	deleterious	-8,7	high_impact	3,77	damaging	0,59	damaging	0,02	deleterious	3,64	23,2	0,03	0,35	disease	0,56	disease	0,9	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	0,25	high_impact	2,03	0,17	0,8	NA	NA	N	0,52	P	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4789	4789	G	A	MI.13436	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	320	107	G	E	gGa/gAa	6,01	1	0	probably_damaging	1	neutral	0,31	neutral	4,32	deleterious	-5,54	deleterious	-7,73	high_impact	4,12	damaging	0,57	damaging	0,02	deleterious	3,79	23,4	0,03	0,35	disease	0,86	disease	0,86	disease	0,77	disease	0,63	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	0,02	high_impact	2,32	0,2	0,8	NA	NA	P	0,67	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4789	4789	G	C	MI.13437	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	320	107	G	A	gGa/gCa	6,01	1	0	probably_damaging	1	neutral	0,61	neutral	4,7	neutral	0,57	deleterious	-5,8	medium_impact	2,4	neutral	0,66	damaging	0,16	deleterious	3,01	22,3	0,07	0,35	neutral	0,47	disease	0,64	neutral	0,39	neutral	0,18	7	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,32	medium_impact	0,88	0,28	0,8	NA	NA	N	0,48	N	0,74	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4791	4791	A	G	MI.13438	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	322	108	M	V	Ata/Gta	-5,27	0	0	probably_damaging	0,98	neutral	0,59	neutral	4,68	neutral	0,73	neutral	-2,2	neutral_impact	0,3	neutral	0,89	neutral	0,48	deleterious	2,5	19,49	0,26	0,45	neutral	0,35	disease	0,72	neutral	0,32	neutral	0,17	7	deleterious	0,98	neutral	0,31	neutral	-2	deleterious	0,74	low_impact	-2,34	medium_impact	0,3	medium_impact	-0,89	0,38	0,8	0,86	6,92	N	0,23	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4791	4791	A	T	MI.13439	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	322	108	M	L	Ata/Tta	-5,27	0	0	probably_damaging	0,96	neutral	0,9	neutral	4,77	neutral	1,72	neutral	-0,26	neutral_impact	-1,3	neutral	0,9	neutral	0,96	deleterious	0,5	7,39	0,32	0,5	disease	0,55	neutral	0,33	neutral	0,23	disease	0,6	2	neutral	0,96	deleterious	0,47	neutral	-2	deleterious	0,68	low_impact	-2,06	medium_impact	0,74	low_impact	-2,24	0,36	0,8	0,86	6,92	N	0,35	N	0,15	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9157	9157	G	A	MI.1344	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	631	211	A	T	Gcc/Acc	0,82	0,99	0	probably_damaging	1	deleterious	0,03	neutral	2,96	deleterious	-6,06	deleterious	-3,51	medium_impact	3,48	neutral	0,77	neutral	0,46	deleterious	4,43	24,2	0,32	0,65	NA	NA	disease	0,84	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,87	low_impact	-3,6	medium_impact	-0,56	medium_impact	1,89	0,68	0,9	50,44	9,14	N	0,4	N	0,8	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4791	4791	A	C	MI.13440	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	322	108	M	L	Ata/Cta	-5,27	0	0	probably_damaging	0,96	neutral	0,9	neutral	4,77	neutral	1,72	neutral	-0,26	neutral_impact	-1,3	neutral	0,9	neutral	0,96	deleterious	0,39	6,52	0,32	0,5	disease	0,55	neutral	0,33	neutral	0,23	disease	0,6	2	neutral	0,96	deleterious	0,47	neutral	-2	deleterious	0,68	low_impact	-2,06	medium_impact	0,74	low_impact	-2,24	0,36	0,8	0,86	6,92	N	0,35	N	0,15	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4792	4792	T	A	MI.13441	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	323	108	M	K	aTa/aAa	-1,58	0	0	probably_damaging	0,99	neutral	0,38	neutral	4,57	neutral	-2,65	deleterious	-4,71	medium_impact	2,23	neutral	0,81	damaging	0,17	deleterious	4,12	23,8	0,03	0,35	disease	0,79	disease	0,87	disease	0,67	disease	0,75	5	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,86	low_impact	-2,62	medium_impact	0,09	medium_impact	0,73	0,17	0,8	0,86	6,92	N	0,23	N	0,93	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4792	4792	T	C	MI.13442	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	323	108	M	T	aTa/aCa	-1,58	0	0	probably_damaging	0,99	neutral	0,44	neutral	4,63	neutral	-1,23	deleterious	-4,16	neutral_impact	0,61	neutral	0,9	neutral	0,31	deleterious	2,84	21,6	0,15	0,4	disease	0,51	disease	0,72	disease	0,57	disease	0,68	4	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,79	low_impact	-2,62	medium_impact	0,15	medium_impact	-0,63	0,18	0,8	0,86	6,92	N	0,33	N	0,8	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4793	4793	A	T	MI.13443	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	324	108	M	I	atA/atT	4,63	0,69	0,11	probably_damaging	0,98	neutral	0,45	neutral	4,73	neutral	0,42	neutral	-1,7	neutral_impact	0,28	neutral	0,84	neutral	0,35	deleterious	3,35	22,9	0,37	0,5	neutral	0,41	disease	0,77	neutral	0,29	neutral	0,18	6	deleterious	0,98	neutral	0,24	neutral	-2	deleterious	0,78	low_impact	-2,34	medium_impact	0,16	medium_impact	-0,91	0,4	0,8	0,86	6,92	N	0,33	N	0,52	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4793	4793	A	C	MI.13444	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	324	108	M	I	atA/atC	4,63	0,69	0,11	probably_damaging	0,98	neutral	0,45	neutral	4,73	neutral	0,42	neutral	-1,7	neutral_impact	0,28	neutral	0,84	neutral	0,35	deleterious	3,18	22,7	0,37	0,5	neutral	0,41	disease	0,77	neutral	0,29	neutral	0,18	6	deleterious	0,98	neutral	0,24	neutral	-2	deleterious	0,78	low_impact	-2,34	medium_impact	0,16	medium_impact	-0,91	0,4	0,8	0,86	6,92	N	0,32	N	0,52	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4794	4794	G	A	MI.13445	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	325	109	A	T	Gcc/Acc	-1,81	0	0	benign	0,17	neutral	0,4	neutral	4,47	neutral	-2,64	neutral	-2,12	medium_impact	2,58	neutral	0,93	neutral	0,85	deleterious	4,03	23,6	0,15	0,4	disease	0,73	disease	0,76	disease	0,53	neutral	0,33	3	neutral	0,52	deleterious	0,62	neutral	-3	deleterious	0,53	medium_impact	-0,17	medium_impact	0,11	medium_impact	1,03	0,69	0,85	NA	NA	N	0,32	N	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4794	4794	G	C	MI.13446	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	325	109	A	P	Gcc/Ccc	-1,81	0	0	probably_damaging	0,98	neutral	0,24	neutral	4,43	deleterious	-4,2	deleterious	-3,79	medium_impact	2,65	neutral	0,89	neutral	0,39	deleterious	3,66	23,2	0,03	0,35	disease	0,96	disease	0,88	disease	0,52	disease	0,62	2	deleterious	0,98	neutral	0,13	deleterious	1	deleterious	0,9	low_impact	-2,34	medium_impact	-0,07	medium_impact	1,09	0,58	0,8	NA	NA	N	0,42	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4794	4794	G	T	MI.13447	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	325	109	A	S	Gcc/Tcc	-1,81	0	0	possibly_damaging	0,79	neutral	0,41	neutral	4,48	neutral	-2,85	neutral	-1,2	medium_impact	2,56	neutral	0,81	neutral	0,94	deleterious	2,02	16,34	0,17	0,45	neutral	0,48	disease	0,61	neutral	0,38	neutral	0,17	7	neutral	0,79	neutral	0,31	NA	0	deleterious	0,73	low_impact	-1,32	medium_impact	0,12	medium_impact	1,01	0,56	0,8	NA	NA	N	0,37	N	0,33	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4795	4795	C	T	MI.13448	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	326	109	A	V	gCc/gTc	0,95	0,04	0	possibly_damaging	0,79	neutral	0,53	neutral	4,58	neutral	1,02	deleterious	-3,26	low_impact	1,92	neutral	0,84	neutral	0,71	deleterious	4,26	23,9	0,13	0,4	disease	0,75	disease	0,5	neutral	0,41	neutral	0,3	4	neutral	0,77	neutral	0,37	neutral	-3	deleterious	0,76	low_impact	-1,32	medium_impact	0,24	medium_impact	0,47	0,7	0,85	NA	NA	N	0,3	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4795	4795	C	A	MI.13449	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	326	109	A	D	gCc/gAc	0,95	0,04	0	probably_damaging	0,97	neutral	0,2	neutral	4,42	deleterious	-5,21	deleterious	-4,22	high_impact	3,94	neutral	0,84	neutral	0,35	deleterious	4,51	24,3	0,02	0,35	disease	0,97	disease	0,9	disease	0,72	disease	0,64	3	neutral	0,98	neutral	0,12	deleterious	2	deleterious	0,88	low_impact	-2,18	medium_impact	-0,13	high_impact	2,17	0,41	0,8	NA	NA	N	0,43	N	0,96	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9157	9157	G	C	MI.1345	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	631	211	A	P	Gcc/Ccc	0,82	0,99	0	probably_damaging	1	deleterious	0	neutral	2,94	deleterious	-7,69	deleterious	-4,46	high_impact	3,58	neutral	0,71	neutral	0,45	deleterious	3,97	23,6	0,17	0,65	NA	NA	disease	0,93	disease	0,68	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,93	low_impact	-3,6	low_impact	-1,4	medium_impact	1,97	0,63	0,9	50,44	9,14	N	0,36	N	0,97	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4795	4795	C	G	MI.13450	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	326	109	A	G	gCc/gGc	0,95	0,04	0	possibly_damaging	0,88	neutral	0,35	neutral	4,44	deleterious	-3,71	deleterious	-3,02	medium_impact	2,84	neutral	0,89	neutral	0,52	deleterious	3,86	23,5	0,14	0,4	disease	0,88	disease	0,75	disease	0,6	disease	0,64	3	neutral	0,89	neutral	0,24	NA	0	deleterious	0,83	low_impact	-1,59	medium_impact	0,06	medium_impact	1,25	0,7	0,85	NA	NA	N	0,42	N	0,61	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4797	4797	C	A	MI.13451	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	328	110	P	T	Ccc/Acc	-5,27	0	0	probably_damaging	1	neutral	0,4	neutral	4,11	deleterious	-8,39	deleterious	-7,73	high_impact	4,15	neutral	0,81	damaging	0,08	deleterious	3,6	23,2	0,03	0,35	disease	0,61	disease	0,85	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	0,11	high_impact	2,35	0,56	0,8	NA	NA	N	0,36	N	0,88	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4797	4797	C	T	MI.13452	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	328	110	P	S	Ccc/Tcc	-5,27	0	0	probably_damaging	1	neutral	0,45	neutral	4,09	deleterious	-8,04	deleterious	-7,73	high_impact	4,15	neutral	0,91	damaging	0,12	deleterious	3,78	23,4	0,04	0,35	neutral	0,48	disease	0,84	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0,16	high_impact	2,35	0,17	0,8	NA	NA	N	0,41	N	0,72	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4797	4797	C	G	MI.13453	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	328	110	P	A	Ccc/Gcc	-5,27	0	0	probably_damaging	1	neutral	0,53	neutral	4,13	deleterious	-7,74	deleterious	-7,73	high_impact	3,81	neutral	0,82	damaging	0,13	deleterious	2,99	22,2	0,05	0,35	disease	0,6	disease	0,73	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	0,24	high_impact	2,06	0,61	0,8	NA	NA	N	0,31	N	0,72	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4798	4798	C	T	MI.13454	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	329	110	P	L	cCc/cTc	5,55	1	0	probably_damaging	1	neutral	0,71	neutral	4,2	deleterious	-9,47	deleterious	-9,67	high_impact	3,81	neutral	0,74	damaging	0,08	deleterious	4,32	24	0,02	0,35	disease	0,66	disease	0,86	disease	0,74	disease	0,68	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,42	high_impact	2,06	0,56	0,8	NA	NA	P	0,56	P	0,97	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4798	4798	C	G	MI.13455	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	329	110	P	R	cCc/cGc	5,55	1	0	probably_damaging	1	neutral	0,35	neutral	4,07	deleterious	-10,42	deleterious	-8,7	high_impact	4,15	neutral	0,83	damaging	0,08	deleterious	3,52	23,1	0,02	0,35	disease	0,57	disease	0,92	disease	0,83	disease	0,73	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	0,06	high_impact	2,35	0,33	0,8	NA	NA	P	0,61	P	0,56	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4798	4798	C	A	MI.13456	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	329	110	P	H	cCc/cAc	5,55	1	0	probably_damaging	1	neutral	0,57	neutral	4,06	deleterious	-11,4	deleterious	-8,7	high_impact	4,15	neutral	0,81	damaging	0,08	deleterious	3,95	23,6	0,03	0,35	disease	0,71	disease	0,86	disease	0,83	disease	0,71	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,28	high_impact	2,35	0,31	0,8	NA	NA	P	0,62	P	0,71	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4800	4800	T	G	MI.13457	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	331	111	F	V	Ttt/Gtt	-6,88	0	0	possibly_damaging	0,77	neutral	0,58	neutral	4,32	neutral	-2,74	deleterious	-6,5	medium_impact	2,01	neutral	0,91	damaging	0,17	deleterious	3,97	23,6	0,06	0,35	disease	0,73	disease	0,86	disease	0,55	neutral	0,31	4	neutral	0,73	neutral	0,41	NA	0	deleterious	0,74	low_impact	-1,28	medium_impact	0,29	medium_impact	0,55	0,39	0,8	0,58	7,14	N	0,27	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4800	4800	T	A	MI.13458	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	331	111	F	I	Ttt/Att	-6,88	0	0	possibly_damaging	0,77	neutral	0,45	neutral	4,28	deleterious	-3,68	deleterious	-5,53	medium_impact	2,21	neutral	0,86	damaging	0,15	deleterious	4,26	23,9	0,09	0,35	disease	0,78	disease	0,88	disease	0,67	disease	0,67	3	neutral	0,76	neutral	0,34	NA	0	deleterious	0,76	low_impact	-1,28	medium_impact	0,16	medium_impact	0,72	0,5	0,8	0,58	7,14	N	0,31	N	0,93	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4800	4800	T	C	MI.13459	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	331	111	F	L	Ttt/Ctt	-6,88	0	0	benign	0,09	neutral	0,86	neutral	4,74	neutral	-0,93	deleterious	-5,47	low_impact	1,23	neutral	0,88	neutral	0,3	deleterious	2,75	21,1	0,12	0,4	disease	0,67	disease	0,65	neutral	0,47	neutral	0,21	6	neutral	0,05	deleterious	0,89	neutral	-6	neutral	0,27	medium_impact	0,12	medium_impact	0,65	medium_impact	-0,11	0,66	0,8	0,58	7,14	N	0,21	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9157	9157	G	T	MI.1346	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	631	211	A	S	Gcc/Tcc	0,82	0,99	0	probably_damaging	0,99	neutral	0,51	neutral	3,14	deleterious	-4,86	deleterious	-2,63	medium_impact	2,1	neutral	0,76	neutral	0,61	deleterious	3,8	23,4	0,25	0,65	NA	NA	disease	0,71	disease	0,51	disease	0,5	0	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,87	low_impact	-2,65	medium_impact	0,3	medium_impact	0,7	0,73	0,9	50,44	9,14	N	0,36	N	0,95	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4801	4801	T	C	MI.13460	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	332	111	F	S	tTt/tCt	1,87	0,97	0	probably_damaging	0,96	neutral	0,5	neutral	4,22	deleterious	-4,4	deleterious	-7,53	medium_impact	3,25	neutral	0,84	damaging	0,15	deleterious	4,07	23,7	0,02	0,35	neutral	0,5	disease	0,86	disease	0,69	disease	0,69	4	neutral	0,96	neutral	0,27	deleterious	1	deleterious	0,78	low_impact	-2,06	medium_impact	0,21	medium_impact	1,59	0,29	0,8	0,58	7,14	N	0,43	N	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4801	4801	T	G	MI.13461	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	332	111	F	C	tTt/tGt	1,87	0,97	0	probably_damaging	0,99	neutral	0,2	neutral	4,27	deleterious	-5,82	deleterious	-7,5	medium_impact	2,65	neutral	0,8	damaging	0,15	deleterious	4,02	23,6	0,03	0,35	disease	0,92	disease	0,89	disease	0,72	disease	0,62	2	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,83	low_impact	-2,62	medium_impact	-0,13	medium_impact	1,09	0,26	0,8	0,58	7,14	N	0,4	N	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4801	4801	T	A	MI.13462	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	332	111	F	Y	tTt/tAt	1,87	0,97	0	probably_damaging	0,93	neutral	1	neutral	4,21	deleterious	-5,17	deleterious	-2,83	high_impact	3,8	neutral	0,88	damaging	0,13	deleterious	4,08	23,7	0,13	0,4	disease	0,84	disease	0,81	disease	0,71	disease	0,65	3	neutral	0,93	deleterious	0,54	deleterious	2	deleterious	0,82	low_impact	-1,83	high_impact	1,87	high_impact	2,05	0,64	0,8	0,58	7,14	N	0,43	N	0,88	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4802	4802	T	A	MI.13463	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	333	111	F	L	ttT/ttA	7,4	1	0	benign	0,09	neutral	0,86	neutral	4,74	neutral	-0,93	deleterious	-5,47	low_impact	1,23	neutral	0,88	neutral	0,3	deleterious	3,18	22,7	0,12	0,4	disease	0,67	disease	0,65	neutral	0,47	neutral	0,21	6	neutral	0,05	deleterious	0,89	neutral	-6	neutral	0,27	medium_impact	0,12	medium_impact	0,65	medium_impact	-0,11	0,66	0,8	0,58	7,14	N	0,52	P	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4802	4802	T	G	MI.13464	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	333	111	F	L	ttT/ttG	7,4	1	0	benign	0,09	neutral	0,86	neutral	4,74	neutral	-0,93	deleterious	-5,47	low_impact	1,23	neutral	0,88	neutral	0,3	deleterious	3,1	22,5	0,12	0,4	disease	0,67	disease	0,65	neutral	0,47	neutral	0,21	6	neutral	0,05	deleterious	0,89	neutral	-6	neutral	0,27	medium_impact	0,12	medium_impact	0,65	medium_impact	-0,11	0,66	0,8	0,58	7,14	N	0,5	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4803	4803	C	T	MI.13465	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	334	112	H	Y	Cac/Tac	-3,65	0	0	probably_damaging	1	neutral	1	neutral	4,01	deleterious	-5,55	deleterious	-5,8	medium_impact	2,45	neutral	0,62	damaging	0,04	deleterious	3,57	23,1	0,05	0,35	disease	0,64	disease	0,87	disease	0,81	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,87	low_impact	-3,54	high_impact	1,87	medium_impact	0,92	0,28	0,8	NA	NA	N	0,26	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4803	4803	C	G	MI.13466	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	334	112	H	D	Cac/Gac	-3,65	0	0	probably_damaging	1	neutral	0,2	neutral	3,98	deleterious	-5,82	deleterious	-8,7	high_impact	4,12	neutral	0,64	damaging	0,04	deleterious	3,74	23,3	0,05	0,35	disease	0,91	disease	0,83	disease	0,84	disease	0,66	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	-0,13	high_impact	2,32	0,28	0,8	NA	NA	N	0,4	N	0,95	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4803	4803	C	A	MI.13467	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	334	112	H	N	Cac/Aac	-3,65	0	0	probably_damaging	1	neutral	0,31	neutral	4	deleterious	-5,39	deleterious	-6,77	high_impact	4,12	neutral	0,64	damaging	0,04	deleterious	3,74	23,3	0,1	0,4	disease	0,86	disease	0,84	disease	0,8	disease	0,66	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	0,02	high_impact	2,32	0,31	0,8	NA	NA	N	0,38	N	0,97	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4804	4804	A	T	MI.13468	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	335	112	H	L	cAc/cTc	4,4	1	0	probably_damaging	1	neutral	0,65	neutral	3,97	deleterious	-5,65	deleterious	-10,64	high_impact	4,12	neutral	0,68	damaging	0,03	deleterious	3,68	23,3	0,03	0,35	disease	0,65	disease	0,87	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	0,36	high_impact	2,32	0,26	0,8	NA	NA	P	0,58	P	0,97	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4804	4804	A	C	MI.13469	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	335	112	H	P	cAc/cCc	4,4	1	0	probably_damaging	1	neutral	0,22	neutral	3,95	deleterious	-7,11	deleterious	-9,67	high_impact	3,77	neutral	0,61	damaging	0,04	deleterious	3,1	22,5	0,03	0,35	disease	0,83	disease	0,87	disease	0,79	disease	0,67	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,54	medium_impact	-0,1	high_impact	2,03	0,18	0,8	NA	NA	P	0,59	P	0,96	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9158	9158	C	G	MI.1347	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	632	211	A	G	gCc/gGc	7,3	1	0	probably_damaging	0,99	neutral	0,08	neutral	3,02	deleterious	-6,41	deleterious	-3,55	medium_impact	2,34	neutral	0,87	neutral	0,61	deleterious	4,11	23,7	0,28	0,65	NA	NA	disease	0,86	disease	0,53	disease	0,54	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,85	low_impact	-2,65	medium_impact	-0,31	medium_impact	0,91	0,8	0,9	50,44	9,14	N	0,48	N	0,86	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4804	4804	A	G	MI.13470	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	335	112	H	R	cAc/cGc	4,4	1	0	probably_damaging	1	neutral	0,35	neutral	3,99	deleterious	-5,73	deleterious	-7,74	high_impact	4,12	neutral	0,64	damaging	0,04	deleterious	2,88	21,8	0,04	0,35	disease	0,84	disease	0,88	disease	0,82	disease	0,66	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,91	low_impact	-3,54	medium_impact	0,06	high_impact	2,32	0,44	0,8	NA	NA	P	0,62	P	0,98	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4805	4805	C	A	MI.13471	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	336	112	H	Q	caC/caA	6,94	1	0	probably_damaging	1	neutral	0,29	neutral	4,04	deleterious	-4,43	deleterious	-7,74	medium_impact	3,31	neutral	0,66	damaging	0,04	deleterious	3,76	23,4	0,05	0,35	disease	0,85	disease	0,81	disease	0,81	disease	0,66	3	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,87	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,64	0,47	0,8	NA	NA	P	0,62	P	0,94	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4805	4805	C	G	MI.13472	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	336	112	H	Q	caC/caG	6,94	1	0	probably_damaging	1	neutral	0,29	neutral	4,04	deleterious	-4,43	deleterious	-7,74	medium_impact	3,31	neutral	0,66	damaging	0,04	deleterious	3,49	23,1	0,05	0,35	disease	0,85	disease	0,81	disease	0,81	disease	0,66	3	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,87	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,64	0,47	0,8	NA	NA	P	0,62	P	0,94	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4806	4806	T	C	MI.13473	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	337	113	F	L	Ttc/Ctc	0,72	0,98	0	probably_damaging	1	neutral	0,79	neutral	4,68	neutral	-1,04	deleterious	-4,73	medium_impact	2,04	neutral	0,89	neutral	0,73	deleterious	2,99	22,2	0,15	0,45	neutral	0,49	disease	0,64	disease	0,51	neutral	0,15	7	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,53	medium_impact	0,57	0,68	0,85	NA	NA	N	0,46	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4806	4806	T	A	MI.13474	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	337	113	F	I	Ttc/Atc	0,72	0,98	0	probably_damaging	1	neutral	0,36	neutral	4,57	neutral	-1,47	deleterious	-4,95	medium_impact	2,96	neutral	0,88	damaging	0,14	deleterious	4,47	24,2	0,13	0,4	neutral	0,5	disease	0,85	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,07	medium_impact	1,35	0,47	0,8	NA	NA	N	0,5	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4806	4806	T	G	MI.13475	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	337	113	F	V	Ttc/Gtc	0,72	0,98	0	probably_damaging	1	neutral	0,39	neutral	4,6	neutral	-0,99	deleterious	-5,91	medium_impact	3,38	neutral	0,87	damaging	0,15	deleterious	4,06	23,7	0,08	0,35	disease	0,56	disease	0,89	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	0,1	medium_impact	1,7	0,28	0,8	NA	NA	N	0,48	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4807	4807	T	C	MI.13476	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	338	113	F	S	tTc/tCc	1,41	0,98	0	probably_damaging	1	neutral	0,41	neutral	4,53	neutral	-1,58	deleterious	-7,09	medium_impact	2,1	neutral	0,91	damaging	0,25	deleterious	4,08	23,7	0,04	0,35	disease	0,66	disease	0,85	disease	0,66	disease	0,55	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,12	medium_impact	0,62	0,26	0,8	NA	NA	N	0,49	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4807	4807	T	A	MI.13477	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	338	113	F	Y	tTc/tAc	1,41	0,98	0	probably_damaging	1	neutral	0,78	neutral	4,52	deleterious	-3,27	deleterious	-2,69	medium_impact	2,46	neutral	0,92	neutral	0,32	deleterious	4,09	23,7	0,14	0,4	disease	0,86	disease	0,8	disease	0,65	disease	0,61	2	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	0,51	medium_impact	0,93	0,54	0,8	NA	NA	N	0,44	N	0,45	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4807	4807	T	G	MI.13478	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	338	113	F	C	tTc/tGc	1,41	0,98	0	probably_damaging	1	neutral	0,13	neutral	4,49	deleterious	-4,46	deleterious	-6,99	medium_impact	3,23	neutral	0,85	damaging	0,14	deleterious	4,01	23,6	0,04	0,35	disease	0,94	disease	0,88	disease	0,71	disease	0,63	3	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,25	medium_impact	1,57	0,21	0,8	NA	NA	N	0,45	N	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4808	4808	C	G	MI.13479	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	339	113	F	L	ttC/ttG	1,64	0,95	0	probably_damaging	1	neutral	0,79	neutral	4,68	neutral	-1,04	deleterious	-4,73	medium_impact	2,04	neutral	0,89	neutral	0,73	deleterious	3,22	22,7	0,15	0,45	neutral	0,49	disease	0,64	disease	0,51	neutral	0,15	7	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,53	medium_impact	0,57	0,68	0,85	NA	NA	N	0,42	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9158	9158	C	T	MI.1348	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	632	211	A	V	gCc/gTc	7,3	1	0	probably_damaging	1	deleterious	0,04	neutral	2,97	deleterious	-7,68	deleterious	-3,55	high_impact	3,83	neutral	0,72	neutral	0,46	deleterious	4,55	24,4	0,38	0,65	NA	NA	disease	0,9	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,9	low_impact	-3,6	medium_impact	-0,49	high_impact	2,19	0,66	0,9	50,44	9,14	N	0,51	P	0,75	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4808	4808	C	A	MI.13480	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	339	113	F	L	ttC/ttA	1,64	0,95	0	probably_damaging	1	neutral	0,79	neutral	4,68	neutral	-1,04	deleterious	-4,73	medium_impact	2,04	neutral	0,89	neutral	0,73	deleterious	3,47	23	0,15	0,45	neutral	0,49	disease	0,64	disease	0,51	neutral	0,15	7	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,53	medium_impact	0,57	0,68	0,85	NA	NA	N	0,43	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4809	4809	T	G	MI.13481	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	340	114	W	G	Tga/Gga	-4,58	0	0	probably_damaging	1	neutral	0,21	neutral	0,43	deleterious	-11,95	deleterious	-12,57	high_impact	4,15	damaging	0,53	damaging	0,04	deleterious	3,8	23,4	0,02	0,35	disease	0,62	disease	0,83	disease	0,85	disease	0,72	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,11	high_impact	2,35	0,06	0,8	NA	NA	N	0,4	N	0,96	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4809	4809	T	C	MI.13482	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	340	114	W	R	Tga/Cga	-4,58	0	0	probably_damaging	1	neutral	0,25	neutral	0,43	deleterious	-12,85	deleterious	-13,54	high_impact	4,15	neutral	0,65	damaging	0,06	deleterious	3,48	23,1	0,02	0,35	disease	0,82	disease	0,91	disease	0,88	disease	0,68	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	-0,06	high_impact	2,35	0,1	0,8	NA	NA	N	0,4	N	0,97	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4810	4810	G	C	MI.13483	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	341	114	W	S	tGa/tCa	7,4	1	0	probably_damaging	1	neutral	0,35	neutral	0,43	deleterious	-12,98	deleterious	-13,54	high_impact	3,81	damaging	0,45	damaging	0,05	deleterious	3,91	23,5	0,02	0,35	neutral	0,36	disease	0,91	disease	0,84	disease	0,74	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,06	high_impact	2,06	0,06	0,8	NA	NA	P	0,51	P	0,94	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4810	4810	G	T	MI.13484	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	341	114	W	L	tGa/tTa	7,4	1	0	probably_damaging	1	neutral	0,71	neutral	0,43	deleterious	-11,93	deleterious	-12,57	high_impact	4,15	damaging	0,55	damaging	0,04	deleterious	4,17	23,8	0,03	0,35	neutral	0,43	disease	0,81	disease	0,84	disease	0,7	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	0,42	high_impact	2,35	0,08	0,8	NA	NA	P	0,54	P	0,97	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4811	4811	A	T	MI.13485	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	342	114	W	C	tgA/tgT	9,24	1	0	probably_damaging	1	neutral	0,14	neutral	0,43	deleterious	-13,81	deleterious	-12,57	high_impact	4,15	damaging	0,56	damaging	0,04	deleterious	4,02	23,6	0,02	0,35	disease	0,87	disease	0,9	disease	0,86	disease	0,65	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	-0,23	high_impact	2,35	0,09	0,8	NA	NA	P	0,54	P	0,98	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4811	4811	A	C	MI.13486	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	342	114	W	C	tgA/tgC	9,24	1	0	probably_damaging	1	neutral	0,14	neutral	0,43	deleterious	-13,81	deleterious	-12,57	high_impact	4,15	damaging	0,56	damaging	0,04	deleterious	3,89	23,5	0,02	0,35	disease	0,87	disease	0,9	disease	0,86	disease	0,65	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	-0,23	high_impact	2,35	0,09	0,8	NA	NA	P	0,53	P	0,98	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4812	4812	G	C	MI.13487	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	343	115	V	L	Gtc/Ctc	3,94	1	0	benign	0,02	neutral	1	neutral	5,25	neutral	2,87	neutral	-2,25	neutral_impact	0,04	neutral	0,93	neutral	0,89	deleterious	1,88	15,47	0,22	0,45	disease	0,59	neutral	0,15	neutral	0,29	neutral	0,26	5	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,16	medium_impact	0,75	high_impact	1,87	low_impact	-1,11	0,42	0,8	1,44	8,33	N	0,44	N	0,36	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4812	4812	G	T	MI.13488	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	343	115	V	F	Gtc/Ttc	3,94	1	0	possibly_damaging	0,82	neutral	0,78	neutral	4,61	neutral	-0,54	deleterious	-4,37	neutral_impact	0,26	neutral	0,84	neutral	0,58	deleterious	3,77	23,4	0,06	0,35	neutral	0,44	neutral	0,28	neutral	0,34	neutral	0,44	1	neutral	0,79	deleterious	0,48	neutral	-3	deleterious	0,66	low_impact	-1,4	medium_impact	0,51	medium_impact	-0,93	0,42	0,8	1,44	8,33	N	0,41	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4812	4812	G	A	MI.13489	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	343	115	V	I	Gtc/Atc	3,94	1	0	benign	0,06	neutral	0,46	neutral	4,7	neutral	0,58	neutral	-0,7	medium_impact	2,12	neutral	0,92	neutral	0,65	deleterious	3,46	23	0,36	0,5	neutral	0,45	neutral	0,32	neutral	0,49	neutral	0,46	1	neutral	0,49	deleterious	0,7	neutral	-3	neutral	0,19	medium_impact	0,3	medium_impact	0,17	medium_impact	0,64	0,76	0,85	1,44	8,33	P	0,56	P	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9158	9158	C	A	MI.1349	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	632	211	A	D	gCc/gAc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,94	deleterious	-8,91	deleterious	-5,3	high_impact	4,38	neutral	0,87	neutral	0,52	deleterious	4,78	24,7	0,13	0,65	NA	NA	disease	0,95	disease	0,71	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,6	low_impact	-1,4	high_impact	2,66	0,58	0,9	50,44	9,14	N	0,48	N	0,99	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4813	4813	T	G	MI.13490	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	344	115	V	G	gTc/gGc	-0,43	0,62	0	probably_damaging	0,93	neutral	0,35	neutral	4,54	neutral	-2,89	deleterious	-6,57	medium_impact	2,92	neutral	0,88	neutral	0,57	deleterious	3,76	23,4	0,02	0,35	disease	0,87	disease	0,56	disease	0,62	disease	0,67	3	neutral	0,93	neutral	0,21	deleterious	1	deleterious	0,79	low_impact	-1,83	medium_impact	0,06	medium_impact	1,31	0,31	0,8	1,44	8,33	N	0,38	N	0,9	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4813	4813	T	C	MI.13491	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	344	115	V	A	gTc/gCc	-0,43	0,62	0	possibly_damaging	0,51	neutral	0,51	neutral	4,62	neutral	-0,31	deleterious	-3,67	medium_impact	2,38	neutral	0,9	neutral	0,59	deleterious	3,51	23,1	0,12	0,4	disease	0,69	neutral	0,42	disease	0,62	disease	0,67	3	neutral	0,5	deleterious	0,5	NA	0	deleterious	0,59	medium_impact	-0,81	medium_impact	0,22	medium_impact	0,86	0,16	0,8	1,44	8,33	N	0,38	N	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4813	4813	T	A	MI.13492	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	344	115	V	D	gTc/gAc	-0,43	0,62	0	probably_damaging	0,95	neutral	0,2	neutral	4,53	deleterious	-3,97	deleterious	-6,53	medium_impact	2,92	neutral	0,85	neutral	0,45	deleterious	4,58	24,4	0,01	0,35	disease	0,93	disease	0,75	disease	0,74	disease	0,7	4	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,84	low_impact	-1,97	medium_impact	-0,13	medium_impact	1,31	0,14	0,8	1,44	8,33	N	0,32	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4815	4815	C	A	MI.13493	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	346	116	P	T	Cca/Aca	-14,24	0	0	probably_damaging	1	neutral	0,4	neutral	4,14	deleterious	-7,01	deleterious	-7,73	medium_impact	3,31	neutral	0,94	damaging	0,14	deleterious	3,56	23,1	0,06	0,35	disease	0,7	disease	0,76	disease	0,67	neutral	0,37	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	0,11	medium_impact	1,64	0,51	0,8	NA	NA	N	0,35	N	0,88	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4815	4815	C	G	MI.13494	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	346	116	P	A	Cca/Gca	-14,24	0	0	probably_damaging	1	neutral	0,52	neutral	4,16	deleterious	-5,6	deleterious	-7,73	high_impact	4,12	neutral	0,93	damaging	0,15	deleterious	2,97	22,1	0,08	0,35	disease	0,59	disease	0,65	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,23	high_impact	2,32	0,67	0,85	NA	NA	N	0,34	N	0,72	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4815	4815	C	T	MI.13495	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	346	116	P	S	Cca/Tca	-14,24	0	0	probably_damaging	1	neutral	0,42	neutral	4,1	deleterious	-6,26	deleterious	-7,73	high_impact	4,12	neutral	0,89	damaging	0,15	deleterious	3,82	23,4	0,05	0,35	disease	0,75	disease	0,77	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,13	high_impact	2,32	0,17	0,8	NA	NA	N	0,38	N	0,72	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4816	4816	C	T	MI.13496	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	347	116	P	L	cCa/cTa	5,32	1	0	probably_damaging	1	neutral	0,68	neutral	4,22	deleterious	-7,15	deleterious	-9,66	medium_impact	2,8	neutral	0,97	damaging	0,12	deleterious	4,33	24	0,03	0,35	neutral	0,39	disease	0,78	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,39	medium_impact	1,21	0,69	0,85	NA	NA	N	0,45	N	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4816	4816	C	G	MI.13497	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	347	116	P	R	cCa/cGa	5,32	1	0	probably_damaging	1	neutral	0,35	neutral	4,09	deleterious	-8,46	deleterious	-8,7	high_impact	4,12	neutral	0,89	damaging	0,1	deleterious	3,52	23,1	0,03	0,35	disease	0,84	disease	0,86	disease	0,78	disease	0,67	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,06	high_impact	2,32	0,29	0,8	NA	NA	P	0,68	P	0,56	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4816	4816	C	A	MI.13498	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	347	116	P	Q	cCa/cAa	5,32	1	0	probably_damaging	1	neutral	0,31	neutral	4,09	deleterious	-8,55	deleterious	-7,73	high_impact	4,12	neutral	0,84	damaging	0,12	deleterious	4,04	23,7	0,06	0,35	disease	0,85	disease	0,82	disease	0,73	disease	0,63	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,02	high_impact	2,32	0,31	0,8	NA	NA	P	0,62	P	0,83	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4818	4818	G	A	MI.13499	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	349	117	E	K	Gag/Aag	-0,89	0,03	0	probably_damaging	1	neutral	0,84	neutral	4,73	neutral	-0,59	deleterious	-3,86	medium_impact	2,88	neutral	0,9	damaging	0,12	deleterious	4,4	24,1	0,1	0,4	disease	0,82	disease	0,8	disease	0,72	disease	0,66	3	deleterious	1	neutral	0,42	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	0,61	medium_impact	1,28	0,62	0,8	NA	NA	N	0,27	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8590	8590	C	A	MI.135	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	64	22	L	M	Ctg/Atg	-15,14	0	0	possibly_damaging	0,85	neutral	0,12	neutral	4,15	neutral	-2,34	neutral	-1,13	medium_impact	2	neutral	0,89	neutral	0,8	deleterious	2,35	18,51	0,33	0,65	disease	0,77	neutral	0,27	neutral	0,36	disease	0,59	2	neutral	0,94	neutral	0,14	NA	0	deleterious	0,69	low_impact	-1,47	medium_impact	-0,2	medium_impact	0,62	0,6	0,9	25,22	20,33	N	0,51	P	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9160	9160	T	A	MI.1350	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	634	212	Y	N	Tac/Aac	-7,04	0	0	probably_damaging	1	deleterious	0	neutral	3,64	deleterious	-6,57	deleterious	-8,03	high_impact	4,53	damaging	0,5	damaging	0,07	deleterious	4,16	23,8	0,25	0,65	NA	NA	disease	0,92	disease	0,69	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	high_impact	2,78	0,2	0,9	50	8,88	N	0,4	N	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4818	4818	G	C	MI.13500	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	349	117	E	Q	Gag/Cag	-0,89	0,03	0	probably_damaging	1	neutral	0,56	neutral	4,56	neutral	-1,07	deleterious	-2,9	medium_impact	2,35	neutral	0,84	damaging	0,15	deleterious	3,31	22,9	0,22	0,45	disease	0,84	disease	0,69	disease	0,68	disease	0,64	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,27	medium_impact	0,83	0,57	0,8	NA	NA	N	0,18	N	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4819	4819	A	G	MI.13501	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	350	117	E	G	gAg/gGg	7,17	1	0	probably_damaging	1	neutral	0,39	neutral	4,51	neutral	-1,32	deleterious	-6,75	medium_impact	2,47	neutral	0,9	damaging	0,19	deleterious	4,16	23,8	0,06	0,35	disease	0,71	disease	0,68	disease	0,69	disease	0,64	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	0,1	medium_impact	0,94	0,25	0,8	NA	NA	P	0,63	P	0,45	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4819	4819	A	C	MI.13502	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	350	117	E	A	gAg/gCg	7,17	1	0	probably_damaging	1	neutral	0,74	neutral	4,58	neutral	-0,42	deleterious	-5,79	medium_impact	2,67	neutral	0,88	damaging	0,17	deleterious	3,61	23,2	0,05	0,35	disease	0,54	disease	0,67	disease	0,66	disease	0,64	3	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,46	medium_impact	1,1	0,33	0,8	NA	NA	N	0,52	P	0,73	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4819	4819	A	T	MI.13503	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	350	117	E	V	gAg/gTg	7,17	1	0	probably_damaging	1	neutral	0,37	neutral	4,51	neutral	-2,36	deleterious	-6,76	medium_impact	3,22	neutral	0,85	damaging	0,15	deleterious	4,14	23,8	0,03	0,35	disease	0,53	disease	0,83	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,08	medium_impact	1,57	0,27	0,8	NA	NA	N	0,55	P	0,81	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4820	4820	G	T	MI.13504	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	351	117	E	D	gaG/gaT	6,94	1	0,07	probably_damaging	1	neutral	0,58	neutral	4,78	neutral	3,12	deleterious	-2,9	medium_impact	2	neutral	0,85	damaging	0,24	deleterious	3,82	23,4	0,29	0,45	disease	0,91	neutral	0,42	neutral	0,34	disease	0,58	2	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,29	medium_impact	0,54	0,53	0,8	NA	NA	N	0,5	N	0,85	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4820	4820	G	C	MI.13505	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	351	117	E	D	gaG/gaC	6,94	1	0,07	probably_damaging	1	neutral	0,58	neutral	4,78	neutral	3,12	deleterious	-2,9	medium_impact	2	neutral	0,85	damaging	0,24	deleterious	3,65	23,2	0,29	0,45	disease	0,91	neutral	0,42	neutral	0,34	disease	0,58	2	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,29	medium_impact	0,54	0,53	0,8	NA	NA	N	0,49	N	0,85	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4821	4821	G	C	MI.13506	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	352	118	V	L	Gtt/Ctt	1,87	1	0	probably_damaging	1	neutral	0,54	neutral	4,31	deleterious	-3,52	deleterious	-2,87	medium_impact	2,6	neutral	0,82	damaging	0,18	deleterious	3,46	23	0,06	0,35	disease	0,51	disease	0,6	disease	0,59	disease	0,64	3	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,25	medium_impact	1,04	0,33	0,8	NA	NA	N	0,39	N	0,76	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4821	4821	G	A	MI.13507	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	352	118	V	I	Gtt/Att	1,87	1	0	probably_damaging	1	neutral	0,31	neutral	4,3	deleterious	-3,75	neutral	-0,93	low_impact	1,79	neutral	0,9	damaging	0,12	deleterious	3,58	23,2	0,25	0,45	disease	0,61	neutral	0,45	neutral	0,46	disease	0,53	1	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	0,02	medium_impact	0,36	0,7	0,85	NA	NA	N	0,53	P	0,46	polymorphism	1	0,03	rs878983010	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4821	4821	G	T	MI.13508	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	352	118	V	F	Gtt/Ttt	1,87	1	0	probably_damaging	1	neutral	0,38	neutral	4,29	deleterious	-4,88	deleterious	-4,8	high_impact	4,02	neutral	0,8	damaging	0,09	deleterious	3,78	23,4	0,02	0,35	neutral	0,42	disease	0,85	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	0,09	high_impact	2,24	0,36	0,8	NA	NA	N	0,43	N	0,95	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4822	4822	T	A	MI.13509	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	353	118	V	D	gTt/gAt	4,17	1	0	probably_damaging	1	neutral	0,12	neutral	4,29	deleterious	-5,12	deleterious	-6,75	high_impact	4,02	neutral	0,88	damaging	0,09	deleterious	4,38	24,1	0,01	0,35	disease	0,92	disease	0,81	disease	0,74	disease	0,63	3	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	-0,27	high_impact	2,24	0,12	0,8	NA	NA	P	0,58	P	0,92	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9160	9160	T	C	MI.1351	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	634	212	Y	H	Tac/Cac	-7,04	0	0	probably_damaging	1	deleterious	0	neutral	3,7	deleterious	-3,96	deleterious	-4,46	high_impact	3,84	damaging	0,54	damaging	0,05	deleterious	3,7	23,3	0,29	0,65	NA	NA	disease	0,9	disease	0,72	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,6	low_impact	-1,4	high_impact	2,19	0,27	0,9	50	8,88	N	0,3	N	0,99	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4822	4822	T	G	MI.13510	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	353	118	V	G	gTt/gGt	4,17	1	0	probably_damaging	1	neutral	0,23	neutral	4,31	deleterious	-3,7	deleterious	-6,76	high_impact	4,02	neutral	0,93	damaging	0,13	deleterious	3,76	23,4	0,01	0,35	neutral	0,47	disease	0,69	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,75	low_impact	-3,54	medium_impact	-0,08	high_impact	2,24	0,15	0,8	NA	NA	P	0,59	P	0,88	polymorphism	1	0,12	rs28571027	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4822	4822	T	C	MI.13511	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	353	118	V	A	gTt/gCt	4,17	1	0	probably_damaging	1	neutral	0,36	neutral	4,91	neutral	0,93	deleterious	-3,87	medium_impact	2,92	neutral	0,93	damaging	0,15	deleterious	3,45	23	0,05	0,35	neutral	0,39	disease	0,57	disease	0,6	disease	0,64	3	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,07	medium_impact	1,31	0,11	0,8	NA	NA	P	0,56	P	0,52	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4824	4824	A	G	MI.13512	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	355	119	T	A	Acc/Gcc	-14,7	0	0,17	benign	0,36	neutral	0,42	neutral	4,64	neutral	-0,37	deleterious	-4,25	low_impact	0,86	neutral	0,98	neutral	0,83	deleterious	2,31	18,24	0,21	0,45	disease	0,55	neutral	0,3	neutral	0,49	disease	0,58	2	neutral	0,51	deleterious	0,53	neutral	-6	deleterious	0,44	medium_impact	-0,57	medium_impact	0,13	medium_impact	-0,42	0,34	0,8	0,86	7,2	N	0,4	N	0,84	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4824	4824	A	C	MI.13513	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	355	119	T	P	Acc/Ccc	-14,7	0	0,17	probably_damaging	0,99	neutral	0,23	neutral	4,58	neutral	-2,8	deleterious	-5,49	medium_impact	2,33	neutral	0,79	neutral	0,61	deleterious	3,4	23	0,06	0,35	disease	0,75	disease	0,7	disease	0,78	disease	0,71	4	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,79	low_impact	-2,62	medium_impact	-0,08	medium_impact	0,82	0,44	0,8	0,86	7,2	N	0,34	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4824	4824	A	T	MI.13514	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	355	119	T	S	Acc/Tcc	-14,7	0	0,17	possibly_damaging	0,87	neutral	0,46	neutral	4,61	neutral	-1,13	deleterious	-3,53	low_impact	1,04	neutral	0,86	neutral	0,55	deleterious	3,23	22,8	0,32	0,5	disease	0,66	neutral	0,34	disease	0,64	disease	0,66	3	neutral	0,86	neutral	0,3	neutral	-3	deleterious	0,68	low_impact	-1,55	medium_impact	0,17	medium_impact	-0,27	0,64	0,8	0,86	7,2	N	0,33	N	0,71	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4825	4825	C	T	MI.13515	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	356	119	T	I	aCc/aTc	-0,2	0	0	probably_damaging	0,97	neutral	0,37	neutral	4,68	neutral	-0,78	deleterious	-5,42	low_impact	0,82	neutral	0,86	neutral	0,5	deleterious	2,83	21,5	0,16	0,45	neutral	0,45	neutral	0,39	neutral	0,49	neutral	0,45	1	neutral	0,97	neutral	0,2	neutral	-2	deleterious	0,68	low_impact	-2,18	medium_impact	0,08	medium_impact	-0,45	0,64	0,8	0,86	7,2	N	0,27	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4825	4825	C	A	MI.13516	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	356	119	T	N	aCc/aAc	-0,2	0	0	probably_damaging	0,98	neutral	0,29	neutral	4,59	neutral	-1,97	deleterious	-4,64	medium_impact	2,33	neutral	0,84	neutral	0,52	deleterious	3,58	23,2	0,28	0,45	disease	0,83	disease	0,56	disease	0,69	disease	0,68	4	deleterious	0,98	neutral	0,16	deleterious	1	deleterious	0,76	low_impact	-2,34	medium_impact	-0,01	medium_impact	0,82	0,52	0,8	0,86	7,2	N	0,33	N	0,91	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4825	4825	C	G	MI.13517	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	356	119	T	S	aCc/aGc	-0,2	0	0	possibly_damaging	0,87	neutral	0,46	neutral	4,61	neutral	-1,13	deleterious	-3,53	low_impact	1,04	neutral	0,86	neutral	0,55	deleterious	3,46	23	0,32	0,5	disease	0,66	neutral	0,34	disease	0,64	disease	0,66	3	neutral	0,86	neutral	0,3	neutral	-3	deleterious	0,68	low_impact	-1,55	medium_impact	0,17	medium_impact	-0,27	0,64	0,8	0,86	7,2	N	0,3	N	0,71	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4827	4827	C	A	MI.13518	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	358	120	Q	K	Caa/Aaa	-15,17	0	0	probably_damaging	0,99	neutral	0,38	neutral	4,6	neutral	-1,32	deleterious	-3,9	medium_impact	2,38	neutral	0,88	damaging	0,14	deleterious	3,92	23,5	0,27	0,45	disease	0,63	disease	0,77	disease	0,61	disease	0,66	3	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,82	low_impact	-2,62	medium_impact	0,09	medium_impact	0,86	0,33	0,8	NA	NA	N	0,26	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4827	4827	C	G	MI.13519	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	358	120	Q	E	Caa/Gaa	-15,17	0	0	probably_damaging	0,99	neutral	0,38	neutral	4,84	neutral	0,98	deleterious	-2,93	low_impact	1,44	neutral	0,81	damaging	0,13	deleterious	3	22,2	0,27	0,45	disease	0,7	disease	0,68	disease	0,6	disease	0,65	3	deleterious	0,99	neutral	0,2	neutral	-2	deleterious	0,76	low_impact	-2,62	medium_impact	0,09	medium_impact	0,07	0,49	0,8	NA	NA	N	0,22	N	0,9	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9160	9160	T	G	MI.1352	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	634	212	Y	D	Tac/Gac	-7,04	0	0	probably_damaging	1	deleterious	0	neutral	3,64	deleterious	-7,72	deleterious	-8,92	high_impact	4,53	damaging	0,51	damaging	0,06	deleterious	4,13	23,8	0,15	0,65	NA	NA	disease	0,94	disease	0,76	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,6	low_impact	-1,4	high_impact	2,78	0,22	0,9	50	8,88	N	0,41	N	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4828	4828	A	G	MI.13520	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	359	120	Q	R	cAa/cGa	5,32	1	0	probably_damaging	0,99	neutral	0,39	neutral	4,57	neutral	-1,85	deleterious	-3,9	medium_impact	3,1	neutral	0,8	damaging	0,13	deleterious	3,36	22,9	0,23	0,45	disease	0,73	disease	0,8	disease	0,64	disease	0,66	3	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,84	low_impact	-2,62	medium_impact	0,1	medium_impact	1,47	0,23	0,8	NA	NA	P	0,57	P	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4828	4828	A	C	MI.13521	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	359	120	Q	P	cAa/cCa	5,32	1	0	probably_damaging	1	neutral	0,23	neutral	4,53	neutral	-2,04	deleterious	-5,86	medium_impact	3,21	neutral	0,87	damaging	0,14	deleterious	3,24	22,8	0,04	0,35	disease	0,85	disease	0,8	disease	0,52	disease	0,61	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,08	medium_impact	1,56	0,19	0,8	NA	NA	P	0,57	P	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4828	4828	A	T	MI.13522	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	359	120	Q	L	cAa/cTa	5,32	1	0	probably_damaging	1	neutral	0,74	neutral	4,56	deleterious	-3,03	deleterious	-6,83	medium_impact	3,21	neutral	0,81	damaging	0,12	deleterious	3,76	23,3	0,09	0,35	disease	0,83	disease	0,81	disease	0,58	disease	0,63	3	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,46	medium_impact	1,56	0,15	0,8	NA	NA	N	0,43	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4829	4829	A	C	MI.13523	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	360	120	Q	H	caA/caC	6,71	1	0	probably_damaging	1	neutral	0,55	neutral	4,54	neutral	-2,24	deleterious	-4,88	medium_impact	3,21	neutral	0,81	damaging	0,12	deleterious	3,35	22,9	0,22	0,45	disease	0,78	disease	0,76	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,26	medium_impact	1,56	0,28	0,8	NA	NA	P	0,53	P	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4829	4829	A	T	MI.13524	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	360	120	Q	H	caA/caT	6,71	1	0	probably_damaging	1	neutral	0,55	neutral	4,54	neutral	-2,24	deleterious	-4,88	medium_impact	3,21	neutral	0,81	damaging	0,12	deleterious	3,48	23,1	0,22	0,45	disease	0,78	disease	0,76	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,26	medium_impact	1,56	0,28	0,8	NA	NA	P	0,53	P	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4830	4830	G	T	MI.13525	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	361	121	G	C	Ggc/Tgc	2,1	1	0	probably_damaging	1	neutral	0,15	neutral	4,32	deleterious	-7,08	deleterious	-8,78	medium_impact	3,5	neutral	0,71	damaging	0,2	deleterious	4,06	23,7	0,07	0,35	disease	0,83	disease	0,88	disease	0,6	disease	0,63	3	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,87	low_impact	-3,54	medium_impact	-0,21	medium_impact	1,8	0,08	0,8	0,29	7,8	N	0,49	N	0,96	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4830	4830	G	C	MI.13526	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	361	121	G	R	Ggc/Cgc	2,1	1	0	probably_damaging	1	neutral	0,61	neutral	4,38	deleterious	-3,69	deleterious	-7,8	high_impact	4,05	neutral	0,88	damaging	0,27	deleterious	3,9	23,5	0,07	0,35	disease	0,92	disease	0,87	disease	0,67	disease	0,6	2	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	0,32	high_impact	2,27	0,5	0,8	0,29	7,8	N	0,49	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4830	4830	G	A	MI.13527	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	361	121	G	S	Ggc/Agc	2,1	1	0	probably_damaging	1	neutral	0,86	neutral	4,44	neutral	-2,91	deleterious	-5,85	medium_impact	2,19	neutral	0,79	neutral	0,38	deleterious	4,16	23,8	0,13	0,4	disease	0,8	disease	0,81	neutral	0,49	disease	0,61	2	deleterious	1	neutral	0,43	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0,65	medium_impact	0,7	0,35	0,8	0,29	7,8	N	0,36	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4831	4831	G	A	MI.13528	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	362	121	G	D	gGc/gAc	6,01	1	0,01	probably_damaging	1	neutral	0,64	neutral	4,38	deleterious	-3,71	deleterious	-6,83	high_impact	3,7	neutral	0,7	damaging	0,24	deleterious	3,8	23,4	0,08	0,35	disease	0,68	disease	0,87	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,35	medium_impact	1,97	0,08	0,8	0,29	7,8	P	0,57	P	0,95	polymorphism	1	0,1	.	.	.	.	.	pituitary oncocytoma	.	.	.	.	.	.	.	.	.
chrM	4831	4831	G	T	MI.13529	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	362	121	G	V	gGc/gTc	6,01	1	0,01	probably_damaging	1	neutral	0,5	neutral	4,35	deleterious	-4,12	deleterious	-8,78	medium_impact	3,5	neutral	0,64	damaging	0,28	deleterious	3,71	23,3	0,06	0,35	disease	0,68	disease	0,86	disease	0,61	disease	0,68	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0,21	medium_impact	1,8	0,08	0,8	0,29	7,8	P	0,57	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9161	9161	A	T	MI.1353	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	635	212	Y	F	tAc/tTc	5,68	1	0	probably_damaging	0,99	neutral	0,09	neutral	4,26	neutral	-0,36	deleterious	-3,57	medium_impact	2,85	damaging	0,54	damaging	0,07	deleterious	3,59	23,2	0,24	0,65	NA	NA	disease	0,91	disease	0,61	disease	0,67	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,91	low_impact	-2,65	medium_impact	-0,28	medium_impact	1,35	0,35	0,9	50	8,88	N	0,47	N	0,81	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4831	4831	G	C	MI.13530	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	362	121	G	A	gGc/gCc	6,01	1	0,01	probably_damaging	1	neutral	0,88	neutral	4,46	neutral	-2,05	deleterious	-5,85	medium_impact	2,95	neutral	0,72	neutral	0,37	deleterious	3,05	22,4	0,14	0,4	disease	0,64	disease	0,72	neutral	0,48	neutral	0,5	0	deleterious	1	neutral	0,44	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	0,69	medium_impact	1,34	0,2	0,8	0,29	7,8	N	0,49	N	0,74	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4833	4833	A	G	MI.13531	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	364	122	T	A	Acc/Gcc	-9,64	0	0,16	benign	0,33	neutral	0,51	neutral	4,86	neutral	1,3	neutral	-0,96	low_impact	0,88	neutral	0,93	neutral	0,81	neutral	1,69	14,33	0,3	0,45	disease	0,51	neutral	0,21	neutral	0,47	neutral	0,28	4	neutral	0,4	deleterious	0,59	neutral	-6	deleterious	0,45	medium_impact	-0,52	medium_impact	0,22	medium_impact	-0,4	0,28	0,8	3,46	8,46	N	0,35	N	0,31	polymorphism	1	0,02	.	.	.	.	.	.	.	CPD	0,15	A4833G	Diabetes helper mutation,AD,PD	+	-	Reported,haplogroup G marker	2
chrM	4833	4833	A	C	MI.13532	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	364	122	T	P	Acc/Ccc	-9,64	0	0,16	probably_damaging	0,92	neutral	0,24	neutral	4,82	neutral	-1,08	deleterious	-2,77	medium_impact	1,98	neutral	0,75	neutral	0,39	deleterious	3,38	23	0,08	0,35	disease	0,89	disease	0,67	neutral	0,5	disease	0,59	2	neutral	0,94	neutral	0,16	deleterious	1	deleterious	0,8	low_impact	-1,77	medium_impact	-0,07	medium_impact	0,52	0,41	0,8	3,46	8,46	N	0,31	N	0,82	polymorphism	1	0,05	rs386419995	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4833	4833	A	T	MI.13533	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	364	122	T	S	Acc/Tcc	-9,64	0	0,16	possibly_damaging	0,61	neutral	0,58	neutral	4,73	neutral	-0,64	neutral	-1,65	neutral_impact	-0,1	neutral	0,78	neutral	0,96	deleterious	0,49	7,36	0,42	0,55	disease	0,58	neutral	0,06	neutral	0,21	neutral	0,38	2	neutral	0,55	deleterious	0,49	neutral	-3	deleterious	0,57	medium_impact	-0,98	medium_impact	0,29	low_impact	-1,23	0,62	0,8	3,46	8,46	N	0,38	N	0,44	polymorphism	1	0,02	rs386419995	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4834	4834	C	A	MI.13534	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	365	122	T	N	aCc/aAc	0,03	0	0	probably_damaging	0,92	neutral	0,36	neutral	4,61	neutral	-2,7	deleterious	-2,77	medium_impact	2,32	neutral	0,81	neutral	0,58	deleterious	3,51	23,1	0,3	0,45	disease	0,87	neutral	0,43	disease	0,55	disease	0,66	3	neutral	0,93	neutral	0,22	deleterious	1	deleterious	0,73	low_impact	-1,77	medium_impact	0,07	medium_impact	0,81	0,52	0,8	3,46	8,46	N	0,34	N	0,7	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4834	4834	C	G	MI.13535	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	365	122	T	S	aCc/aGc	0,03	0	0	possibly_damaging	0,61	neutral	0,58	neutral	4,73	neutral	-0,64	neutral	-1,65	neutral_impact	-0,1	neutral	0,78	neutral	0,96	deleterious	0,67	8,61	0,42	0,55	disease	0,58	neutral	0,06	neutral	0,21	neutral	0,38	2	neutral	0,55	deleterious	0,49	neutral	-3	deleterious	0,57	medium_impact	-0,98	medium_impact	0,29	low_impact	-1,23	0,62	0,8	3,46	8,46	N	0,38	N	0,44	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4834	4834	C	T	MI.13536	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	365	122	T	I	aCc/aTc	0,03	0	0	benign	0,04	neutral	0,5	neutral	4,68	neutral	-2,1	neutral	1,58	neutral_impact	-0,6	neutral	0,91	neutral	0,96	neutral	-0,61	0,12	0,16	0,45	neutral	0,44	neutral	0,14	neutral	0,2	neutral	0,26	5	neutral	0,46	deleterious	0,73	neutral	-6	neutral	0,17	medium_impact	0,47	medium_impact	0,21	low_impact	-1,65	0,38	0,8	3,46	8,46	N	0,33	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4836	4836	C	G	MI.13537	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	367	123	P	A	Cct/Gct	-9,41	0	0	benign	0,04	neutral	0,78	neutral	4,43	deleterious	-3,91	deleterious	-4,26	medium_impact	2,29	neutral	0,9	neutral	0,66	neutral	1,17	11,58	0,31	0,45	neutral	0,45	neutral	0,21	disease	0,52	neutral	0,43	1	neutral	0,15	deleterious	0,87	neutral	-3	neutral	0,16	medium_impact	0,47	medium_impact	0,51	medium_impact	0,78	0,66	0,8	8,65	7,87	N	0,34	N	0,5	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4836	4836	C	T	MI.13538	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	367	123	P	S	Cct/Tct	-9,41	0	0	benign	0,06	neutral	0,76	neutral	4,51	deleterious	-4,01	deleterious	-3,4	neutral_impact	0,38	neutral	0,89	neutral	0,99	deleterious	0,44	6,98	0,48	0,55	disease	0,57	neutral	0,11	neutral	0,32	neutral	0,3	4	neutral	0,15	deleterious	0,85	neutral	-6	neutral	0,19	medium_impact	0,3	medium_impact	0,49	medium_impact	-0,83	0,12	0,8	8,65	7,87	N	0,35	N	0,5	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4836	4836	C	A	MI.13539	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	367	123	P	T	Cct/Act	-9,41	0	0	benign	0,04	neutral	0,61	neutral	4,6	deleterious	-3,12	deleterious	-3,89	neutral_impact	0,55	neutral	0,92	neutral	0,97	deleterious	0,49	7,36	0,31	0,45	neutral	0,42	neutral	0,12	neutral	0,33	neutral	0,25	5	neutral	0,34	deleterious	0,79	neutral	-6	neutral	0,14	medium_impact	0,47	medium_impact	0,32	medium_impact	-0,68	0,5	0,8	8,65	7,87	N	0,43	N	0,58	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9161	9161	A	C	MI.1354	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	635	212	Y	S	tAc/tCc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	3,65	deleterious	-6,29	deleterious	-8,01	high_impact	4,18	damaging	0,49	damaging	0,09	deleterious	3,88	23,5	0,2	0,65	NA	NA	disease	0,93	disease	0,68	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,6	low_impact	-1,4	high_impact	2,48	0,26	0,9	50	8,88	N	0,42	N	0,99	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4837	4837	C	G	MI.13540	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	368	123	P	R	cCt/cGt	-7,34	0	0	possibly_damaging	0,86	neutral	0,54	neutral	4,4	deleterious	-5,2	deleterious	-5,27	medium_impact	3,1	neutral	0,87	neutral	0,35	deleterious	3,15	22,6	0,1	0,4	disease	0,54	neutral	0,48	disease	0,62	disease	0,63	3	neutral	0,84	neutral	0,34	NA	0	deleterious	0,69	low_impact	-1,52	medium_impact	0,25	medium_impact	1,47	0,37	0,8	8,65	7,87	N	0,3	N	0,86	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4837	4837	C	A	MI.13541	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	368	123	P	H	cCt/cAt	-7,34	0	0	probably_damaging	0,95	neutral	0,17	neutral	4,4	deleterious	-6,14	deleterious	-5,03	medium_impact	1,95	neutral	0,89	neutral	0,81	deleterious	2,7	20,8	0,16	0,45	disease	0,7	neutral	0,39	disease	0,51	disease	0,65	3	neutral	0,97	neutral	0,11	deleterious	1	deleterious	0,7	low_impact	-1,97	medium_impact	-0,17	medium_impact	0,5	0,27	0,8	8,65	7,87	N	0,48	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4837	4837	C	T	MI.13542	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	368	123	P	L	cCt/cTt	-7,34	0	0	possibly_damaging	0,58	neutral	0,38	neutral	4,4	deleterious	-5,13	deleterious	-6,24	medium_impact	2,4	neutral	0,92	neutral	0,55	deleterious	2,43	18,99	0,17	0,45	neutral	0,49	neutral	0,37	disease	0,52	neutral	0,45	1	neutral	0,64	neutral	0,4	NA	0	deleterious	0,54	medium_impact	-0,93	medium_impact	0,09	medium_impact	0,88	0,59	0,8	8,65	7,87	N	0,43	N	0,93	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4839	4839	C	G	MI.13543	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	370	124	L	V	Ctg/Gtg	-9,41	0	0	probably_damaging	1	neutral	0,24	neutral	4,61	neutral	-0,32	deleterious	-2,89	high_impact	3,63	neutral	0,87	damaging	0,14	deleterious	3,39	23	0,39	0,5	disease	0,6	neutral	0,39	disease	0,67	disease	0,61	2	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,74	low_impact	-3,54	medium_impact	-0,07	medium_impact	1,91	0,45	0,8	0,58	7,76	N	0,38	N	0,77	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4839	4839	C	A	MI.13544	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	370	124	L	M	Ctg/Atg	-9,41	0	0	probably_damaging	1	neutral	0,25	neutral	4,52	neutral	-2,02	neutral	-1,85	low_impact	1,21	neutral	0,9	neutral	0,83	deleterious	3,66	23,2	0,34	0,5	disease	0,79	neutral	0,17	neutral	0,42	neutral	0,33	3	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,73	low_impact	-3,54	medium_impact	-0,06	medium_impact	-0,13	0,54	0,8	0,58	7,76	N	0,5	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4840	4840	T	A	MI.13545	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	371	124	L	Q	cTg/cAg	-0,89	0	0	probably_damaging	1	neutral	0,17	neutral	4,5	neutral	-2,93	deleterious	-5,78	high_impact	3,63	neutral	0,89	damaging	0,12	deleterious	3,95	23,6	0,04	0,35	disease	0,94	disease	0,68	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	-0,17	medium_impact	1,91	0,14	0,8	0,58	7,76	N	0,38	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4840	4840	T	G	MI.13546	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	371	124	L	R	cTg/cGg	-0,89	0	0	probably_damaging	1	neutral	0,11	neutral	4,5	neutral	-2,8	deleterious	-5,8	medium_impact	3,29	neutral	0,85	damaging	0,11	deleterious	4,09	23,7	0,03	0,35	disease	0,93	disease	0,75	disease	0,77	disease	0,7	4	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,87	low_impact	-3,54	medium_impact	-0,3	medium_impact	1,63	0,17	0,8	0,58	7,76	N	0,32	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4840	4840	T	C	MI.13547	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	371	124	L	P	cTg/cCg	-0,89	0	0	probably_damaging	1	neutral	0,12	neutral	4,77	neutral	0,88	deleterious	-6,78	medium_impact	3,08	neutral	0,88	damaging	0,12	deleterious	3,83	23,4	0,03	0,35	disease	0,93	disease	0,71	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,27	medium_impact	1,45	0,14	0,8	0,58	7,76	N	0,38	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4842	4842	A	G	MI.13548	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	373	125	T	A	Aca/Gca	-3,42	0	0	benign	0,04	neutral	0,57	neutral	4,67	neutral	0,37	neutral	-1,28	low_impact	1,48	neutral	0,89	neutral	0,81	neutral	-0,33	0,56	0,29	0,45	neutral	0,37	neutral	0,22	neutral	0,46	neutral	0,41	2	neutral	0,38	deleterious	0,77	neutral	-6	neutral	0,14	medium_impact	0,47	medium_impact	0,28	medium_impact	0,1	0,43	0,8	15,85	9,38	N	0,27	N	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4842	4842	A	C	MI.13549	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	373	125	T	P	Aca/Cca	-3,42	0	0	possibly_damaging	0,45	neutral	0,24	neutral	4,62	neutral	0,77	neutral	-2,09	low_impact	0,91	neutral	0,92	neutral	0,8	neutral	1,62	13,98	0,09	0,35	neutral	0,38	disease	0,56	disease	0,53	neutral	0,23	5	neutral	0,73	neutral	0,4	neutral	-3	deleterious	0,53	medium_impact	-0,72	medium_impact	-0,07	medium_impact	-0,38	0,42	0,8	15,85	9,38	N	0,41	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9161	9161	A	G	MI.1355	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	635	212	Y	C	tAc/tGc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	3,64	deleterious	-7,79	deleterious	-8,05	high_impact	4,53	damaging	0,46	damaging	0,05	deleterious	3,7	23,3	0,26	0,65	NA	NA	disease	0,92	disease	0,73	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,6	low_impact	-1,4	high_impact	2,78	0,24	0,9	50	8,88	N	0,45	N	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4842	4842	A	T	MI.13550	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	373	125	T	S	Aca/Tca	-3,42	0	0	benign	0,1	neutral	0,46	neutral	4,68	neutral	0,71	neutral	-0,35	neutral_impact	0,1	neutral	0,83	neutral	0,98	neutral	-1,06	0,01	0,31	0,45	neutral	0,4	neutral	0,12	neutral	0,33	neutral	0,28	4	neutral	0,47	deleterious	0,68	neutral	-6	neutral	0,2	medium_impact	0,08	medium_impact	0,17	low_impact	-1,06	0,64	0,8	15,85	9,38	N	0,38	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4843	4843	C	T	MI.13551	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	374	125	T	M	aCa/aTa	-1,12	0	0	benign	0,01	neutral	0,28	neutral	4,58	neutral	-1,65	neutral	-0,86	neutral_impact	0,66	neutral	0,92	neutral	0,98	deleterious	0,48	7,28	0,17	0,45	neutral	0,48	neutral	0,15	neutral	0,35	neutral	0,25	5	neutral	0,72	deleterious	0,64	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	-0,02	medium_impact	-0,59	0,54	0,8	15,85	9,38	N	0,46	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4843	4843	C	A	MI.13552	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	374	125	T	K	aCa/aAa	-1,12	0	0	benign	0,15	neutral	0,33	neutral	4,67	neutral	-2,47	neutral	-1,33	neutral_impact	0,3	neutral	0,84	neutral	0,91	deleterious	0,86	9,83	0,11	0,4	disease	0,79	neutral	0,37	neutral	0,48	disease	0,64	3	neutral	0,61	deleterious	0,59	neutral	-6	neutral	0,3	medium_impact	-0,11	medium_impact	0,04	medium_impact	-0,89	0,33	0,8	15,85	9,38	N	0,39	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4845	4845	T	C	MI.13553	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	376	126	S	P	Tcc/Ccc	-7,57	0	0	benign	0,02	neutral	0,23	neutral	4,39	deleterious	-4,67	deleterious	-3,04	low_impact	1,26	neutral	0,98	neutral	0,83	deleterious	2,74	21	0,06	0,35	disease	0,96	disease	0,8	disease	0,58	disease	0,7	4	neutral	0,76	deleterious	0,61	neutral	-6	neutral	0,37	medium_impact	0,75	medium_impact	-0,08	medium_impact	-0,08	0,37	0,8	2,02	7,51	N	0,36	N	0,36	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4845	4845	T	A	MI.13554	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	376	126	S	T	Tcc/Acc	-7,57	0	0	possibly_damaging	0,58	neutral	0,48	neutral	4,47	neutral	-1,9	neutral	-2,22	neutral_impact	0,1	neutral	0,88	neutral	0,93	deleterious	2,07	16,69	0,27	0,45	disease	0,72	neutral	0,04	neutral	0,28	neutral	0,33	3	neutral	0,58	neutral	0,45	neutral	-3	deleterious	0,59	medium_impact	-0,93	medium_impact	0,19	low_impact	-1,06	0,63	0,8	2,02	7,51	N	0,4	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4845	4845	T	G	MI.13555	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	376	126	S	A	Tcc/Gcc	-7,57	0	0	benign	0,42	neutral	0,51	neutral	4,46	neutral	0,08	neutral	-2,17	low_impact	1,46	neutral	0,92	neutral	0,88	deleterious	2,59	20,1	0,31	0,45	disease	0,78	neutral	0,33	disease	0,58	disease	0,66	3	neutral	0,44	deleterious	0,55	neutral	-6	deleterious	0,6	medium_impact	-0,67	medium_impact	0,22	medium_impact	0,09	0,51	0,8	2,02	7,51	N	0,38	N	0,33	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4846	4846	C	G	MI.13556	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	377	126	S	C	tCc/tGc	0,26	0	0	probably_damaging	0,96	neutral	0,18	neutral	4,38	deleterious	-4,52	deleterious	-4,18	medium_impact	2,29	neutral	0,82	neutral	0,4	deleterious	3,49	23,1	0,07	0,35	disease	0,96	disease	0,65	disease	0,61	disease	0,78	6	neutral	0,98	neutral	0,11	deleterious	1	deleterious	0,82	low_impact	-2,06	medium_impact	-0,16	medium_impact	0,78	0,34	0,8	2,02	7,51	N	0,32	N	0,51	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4846	4846	C	A	MI.13557	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	377	126	S	Y	tCc/tAc	0,26	0	0	probably_damaging	0,95	neutral	1	neutral	4,39	deleterious	-3,93	deleterious	-4,98	medium_impact	2,63	neutral	0,88	neutral	0,47	deleterious	4,07	23,7	0,05	0,35	disease	0,93	disease	0,65	disease	0,66	disease	0,74	5	neutral	0,95	deleterious	0,53	deleterious	1	deleterious	0,84	low_impact	-1,97	high_impact	1,87	medium_impact	1,07	0,39	0,8	2,02	7,51	N	0,27	N	0,91	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4846	4846	C	T	MI.13558	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	377	126	S	F	tCc/tTc	0,26	0	0	probably_damaging	0,95	neutral	0,73	neutral	4,42	deleterious	-3,21	deleterious	-5,15	medium_impact	2,98	neutral	0,86	neutral	0,46	deleterious	4,11	23,7	0,05	0,35	disease	0,81	disease	0,67	disease	0,65	disease	0,69	4	neutral	0,94	neutral	0,39	deleterious	1	deleterious	0,82	low_impact	-1,97	medium_impact	0,45	medium_impact	1,36	0,22	0,8	2,02	7,51	N	0,22	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4848	4848	G	C	MI.13559	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	379	127	G	R	Ggc/Cgc	-2,5	0	0	probably_damaging	0,97	neutral	0,35	neutral	4,55	deleterious	-3,71	deleterious	-7,03	high_impact	3,52	neutral	0,87	damaging	0,24	deleterious	3,92	23,5	0,03	0,35	disease	0,8	disease	0,84	disease	0,75	disease	0,69	4	neutral	0,97	neutral	0,19	deleterious	2	deleterious	0,86	low_impact	-2,18	medium_impact	0,06	medium_impact	1,82	0,62	0,8	NA	NA	N	0,37	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9163	9163	G	C	MI.1356	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	637	213	V	L	Gtt/Ctt	-3,57	0	0	probably_damaging	0,98	neutral	0,08	neutral	3,16	deleterious	-4,34	deleterious	-2,63	high_impact	3,94	neutral	0,65	neutral	0,58	deleterious	3,66	23,2	0,18	0,65	NA	NA	disease	0,89	disease	0,7	disease	0,74	5	deleterious	0,99	neutral	0,05	deleterious	2	deleterious	0,85	low_impact	-2,36	medium_impact	-0,31	high_impact	2,28	0,39	0,9	48,23	8,71	N	0,42	N	0,7	disease_causing	0,97	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4848	4848	G	T	MI.13560	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	379	127	G	C	Ggc/Tgc	-2,5	0	0	probably_damaging	0,99	neutral	0,18	neutral	4,56	deleterious	-3,97	deleterious	-7,82	low_impact	1,23	neutral	0,83	neutral	0,47	deleterious	4,1	23,7	0,06	0,35	disease	0,84	disease	0,76	neutral	0,46	neutral	0,38	2	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,81	low_impact	-2,62	medium_impact	-0,16	medium_impact	-0,11	0,38	0,8	NA	NA	N	0,35	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4848	4848	G	A	MI.13561	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	379	127	G	S	Ggc/Agc	-2,5	0	0	possibly_damaging	0,77	neutral	0,4	neutral	4,9	neutral	-0,59	deleterious	-4,99	low_impact	1,74	neutral	0,9	neutral	0,7	deleterious	4,08	23,7	0,11	0,4	disease	0,7	disease	0,61	neutral	0,45	neutral	0,22	6	neutral	0,78	neutral	0,32	neutral	-3	deleterious	0,73	low_impact	-1,28	medium_impact	0,11	medium_impact	0,32	0,66	0,8	NA	NA	N	0,46	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4849	4849	G	A	MI.13562	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	380	127	G	D	gGc/gAc	4,17	1	0	probably_damaging	0,95	neutral	0,2	neutral	4,55	deleterious	-4,53	deleterious	-6,21	high_impact	3,52	neutral	0,83	damaging	0,28	deleterious	3,77	23,4	0,02	0,35	disease	0,89	disease	0,83	disease	0,74	disease	0,64	3	neutral	0,97	neutral	0,13	deleterious	2	deleterious	0,83	low_impact	-1,97	medium_impact	-0,13	medium_impact	1,82	0,26	0,8	NA	NA	P	0,55	P	0,95	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4849	4849	G	T	MI.13563	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	380	127	G	V	gGc/gTc	4,17	1	0	possibly_damaging	0,85	neutral	0,5	neutral	4,61	neutral	-0,98	deleterious	-7,83	medium_impact	2,14	neutral	0,86	neutral	0,34	deleterious	3,75	23,3	0,07	0,35	neutral	0,38	disease	0,74	disease	0,63	disease	0,65	3	neutral	0,84	neutral	0,33	NA	0	deleterious	0,72	low_impact	-1,49	medium_impact	0,21	medium_impact	0,66	0,21	0,8	NA	NA	N	0,44	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4849	4849	G	C	MI.13564	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	380	127	G	A	gGc/gCc	4,17	1	0	benign	0,15	neutral	0,51	neutral	4,84	neutral	0,13	deleterious	-4,87	low_impact	0,82	neutral	0,9	neutral	0,63	deleterious	1,96	15,99	0,14	0,4	neutral	0,44	neutral	0,2	neutral	0,42	neutral	0,36	3	neutral	0,4	deleterious	0,68	neutral	-6	neutral	0,33	medium_impact	-0,11	medium_impact	0,22	medium_impact	-0,45	0,52	0,8	NA	NA	P	0,59	P	0,74	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4851	4851	C	G	MI.13565	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	382	128	L	V	Ctg/Gtg	-5,5	0	0	possibly_damaging	0,67	neutral	0,09	neutral	4,33	neutral	-1,54	neutral	-2,05	medium_impact	2,8	neutral	0,95	damaging	0,27	deleterious	3,37	22,9	0,22	0,45	disease	0,78	neutral	0,35	disease	0,51	disease	0,63	3	neutral	0,92	neutral	0,21	NA	0	deleterious	0,69	low_impact	-1,08	medium_impact	-0,35	medium_impact	1,21	0,62	0,8	NA	NA	N	0,48	N	0,5	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4851	4851	C	A	MI.13566	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	382	128	L	M	Ctg/Atg	-5,5	0	0	benign	0,34	neutral	0,17	neutral	4,37	deleterious	-3,14	neutral	-0,02	neutral_impact	0,78	neutral	0,9	neutral	0,84	neutral	1,42	12,89	0,19	0,45	disease	0,85	neutral	0,11	neutral	0,32	neutral	0,42	2	neutral	0,8	neutral	0,42	neutral	-6	deleterious	0,53	medium_impact	-0,53	medium_impact	-0,17	medium_impact	-0,49	0,42	0,8	NA	NA	N	0,54	P	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4852	4852	T	A	MI.13567	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	383	128	L	Q	cTg/cAg	-4,11	0	0	probably_damaging	0,97	neutral	0,14	neutral	4,21	deleterious	-5,36	deleterious	-4,19	high_impact	3,69	neutral	0,89	damaging	0,13	deleterious	4,15	23,8	0,03	0,35	disease	0,92	disease	0,71	disease	0,6	disease	0,65	3	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-2,18	medium_impact	-0,23	medium_impact	1,96	0,36	0,8	NA	NA	N	0,49	N	0,94	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	T4852A	LHON	+	-	Reported	1
chrM	4852	4852	T	C	MI.13568	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	383	128	L	P	cTg/cCg	-4,11	0	0	probably_damaging	0,98	neutral	0,17	neutral	4,21	deleterious	-5,75	deleterious	-5,51	high_impact	3,69	neutral	0,88	damaging	0,1	deleterious	3,87	23,5	0,02	0,35	disease	0,95	disease	0,77	disease	0,71	disease	0,7	4	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-2,34	medium_impact	-0,17	medium_impact	1,96	0,31	0,8	NA	NA	N	0,36	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4852	4852	T	G	MI.13569	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	383	128	L	R	cTg/cGg	-4,11	0	0	probably_damaging	0,97	neutral	0,05	neutral	4,22	deleterious	-5,18	deleterious	-4,57	high_impact	3,69	neutral	0,85	damaging	0,1	deleterious	4,16	23,8	0,02	0,35	disease	0,95	disease	0,78	disease	0,72	disease	0,7	4	deleterious	0,99	neutral	0,04	deleterious	2	deleterious	0,87	low_impact	-2,18	medium_impact	-0,5	medium_impact	1,96	0,24	0,8	NA	NA	N	0,38	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9163	9163	G	A	MI.1357	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	637	213	V	I	Gtt/Att	-3,57	0	0	probably_damaging	0,98	neutral	0,27	neutral	3,77	neutral	-1,01	neutral	-0,86	medium_impact	2,33	neutral	0,84	neutral	0,68	deleterious	3,78	23,4	0,27	0,65	NA	NA	disease	0,72	disease	0,64	disease	0,53	1	deleterious	0,98	neutral	0,15	deleterious	1	deleterious	0,81	low_impact	-2,36	medium_impact	0,05	medium_impact	0,9	0,58	0,9	48,23	8,71	N	0,3	N	0,41	disease_causing	0,92	0,06	rs2298010	.	.	.	.	.	COSM1138420	.	.	.	.	.	.	.	.
chrM	4854	4854	C	G	MI.13570	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	385	129	L	V	Ctt/Gtt	-2,27	0	0	possibly_damaging	0,71	neutral	0,3	neutral	4,36	neutral	-1,54	neutral	-0,01	neutral_impact	0,65	neutral	0,94	neutral	0,87	deleterious	2,25	17,81	0,18	0,45	disease	0,9	neutral	0,3	neutral	0,33	disease	0,64	3	neutral	0,78	neutral	0,3	neutral	-3	deleterious	0,73	low_impact	-1,15	medium_impact	0	medium_impact	-0,6	0,49	0,8	NA	NA	N	0,5	N	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4854	4854	C	T	MI.13571	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	385	129	L	F	Ctt/Ttt	-2,27	0	0	probably_damaging	0,98	neutral	0,24	neutral	4,35	neutral	-1,67	deleterious	-2,53	low_impact	1,32	neutral	0,91	neutral	0,41	deleterious	3,92	23,5	0,15	0,4	disease	0,95	disease	0,51	disease	0,55	disease	0,75	5	deleterious	0,99	neutral	0,13	neutral	-2	deleterious	0,81	low_impact	-2,34	medium_impact	-0,07	medium_impact	-0,03	0,29	0,8	NA	NA	N	0,43	N	0,38	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4854	4854	C	A	MI.13572	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	385	129	L	I	Ctt/Att	-2,27	0	0	benign	0,26	neutral	1	neutral	4,63	neutral	-0,04	neutral	0,77	neutral_impact	-1,27	neutral	0,91	neutral	0,9	neutral	1,38	12,7	0,18	0,45	disease	0,68	neutral	0,02	neutral	0,18	neutral	0,39	2	neutral	0,26	deleterious	0,87	neutral	-6	deleterious	0,46	medium_impact	-0,38	high_impact	1,87	low_impact	-2,21	0,36	0,8	NA	NA	N	0,39	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4855	4855	T	C	MI.13573	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	386	129	L	P	cTt/cCt	0,72	0,19	0	probably_damaging	0,99	neutral	0,14	neutral	4,2	deleterious	-5,72	deleterious	-5,25	medium_impact	2,6	neutral	0,76	damaging	0,2	deleterious	3,82	23,4	0,03	0,35	disease	0,99	disease	0,84	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,89	low_impact	-2,62	medium_impact	-0,23	medium_impact	1,04	0,28	0,8	NA	NA	N	0,31	N	0,88	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4855	4855	T	A	MI.13574	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	386	129	L	H	cTt/cAt	0,72	0,19	0	probably_damaging	0,99	neutral	0,07	neutral	4,2	deleterious	-5,77	deleterious	-5,34	medium_impact	2,6	neutral	0,8	damaging	0,24	deleterious	4,06	23,7	0,04	0,35	disease	1	disease	0,66	disease	0,65	disease	0,8	6	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,84	low_impact	-2,62	medium_impact	-0,42	medium_impact	1,04	0,28	0,8	NA	NA	N	0,29	N	0,79	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4855	4855	T	G	MI.13575	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	386	129	L	R	cTt/cGt	0,72	0,19	0	probably_damaging	0,99	deleterious	0,04	neutral	4,2	deleterious	-5,21	deleterious	-5,04	medium_impact	2,6	neutral	0,76	damaging	0,21	deleterious	4,15	23,8	0,02	0,35	disease	0,99	disease	0,82	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,9	low_impact	-2,62	medium_impact	-0,56	medium_impact	1,04	0,2	0,8	NA	NA	N	0,3	N	0,9	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4857	4857	C	G	MI.13576	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	388	130	L	V	Ctt/Gtt	-5,27	0	0	benign	0,15	neutral	0,17	neutral	4,32	neutral	-1,95	deleterious	-2,52	medium_impact	2,7	neutral	0,95	neutral	0,44	deleterious	3,37	22,9	0,11	0,4	neutral	0,38	neutral	0,39	disease	0,55	neutral	0,45	1	neutral	0,8	deleterious	0,51	neutral	-3	neutral	0,32	medium_impact	-0,11	medium_impact	-0,17	medium_impact	1,13	0,56	0,8	NA	NA	N	0,44	N	0,77	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4857	4857	C	T	MI.13577	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	388	130	L	F	Ctt/Ttt	-5,27	0	0	probably_damaging	0,95	neutral	0,2	neutral	4,29	neutral	-2,34	deleterious	-3,72	medium_impact	3,15	neutral	0,81	damaging	0,12	deleterious	3,92	23,5	0,06	0,35	disease	0,86	disease	0,53	disease	0,61	disease	0,64	3	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,75	low_impact	-1,97	medium_impact	-0,13	medium_impact	1,51	0,38	0,8	NA	NA	N	0,28	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4857	4857	C	A	MI.13578	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	388	130	L	I	Ctt/Att	-5,27	0	0	benign	0,15	neutral	0,4	neutral	4,3	neutral	-2,28	neutral	-1,61	low_impact	1,33	neutral	0,91	neutral	0,84	deleterious	2,93	22	0,14	0,4	neutral	0,47	neutral	0,21	neutral	0,37	neutral	0,35	3	neutral	0,53	deleterious	0,63	neutral	-6	neutral	0,27	medium_impact	-0,11	medium_impact	0,11	medium_impact	-0,03	0,36	0,8	NA	NA	N	0,44	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4858	4858	T	A	MI.13579	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	389	130	L	H	cTt/cAt	-2,73	0	0	probably_damaging	0,99	neutral	0,06	neutral	4,43	neutral	-1,01	deleterious	-6,62	high_impact	3,94	neutral	0,87	damaging	0,1	deleterious	3,95	23,6	0,02	0,35	disease	0,94	disease	0,71	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,81	low_impact	-2,62	medium_impact	-0,46	high_impact	2,17	0,28	0,8	NA	NA	N	0,34	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9163	9163	G	T	MI.1358	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	637	213	V	F	Gtt/Ttt	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	3,07	deleterious	-6,93	deleterious	-4,41	high_impact	3,94	neutral	0,66	neutral	0,54	deleterious	3,97	23,6	0,11	0,65	NA	NA	disease	0,96	disease	0,74	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,28	0,45	0,9	48,23	8,71	N	0,4	N	0,98	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4858	4858	T	G	MI.13580	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	389	130	L	R	cTt/cGt	-2,73	0	0	probably_damaging	0,98	neutral	0,07	neutral	4,22	deleterious	-4,43	deleterious	-5,72	high_impact	3,94	neutral	0,91	damaging	0,13	deleterious	4,02	23,6	0,01	0,35	disease	0,92	disease	0,8	disease	0,74	disease	0,67	3	deleterious	0,99	neutral	0,05	deleterious	2	deleterious	0,86	low_impact	-2,34	medium_impact	-0,42	high_impact	2,17	0,2	0,8	NA	NA	N	0,44	N	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4858	4858	T	C	MI.13581	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	389	130	L	P	cTt/cCt	-2,73	0	0	probably_damaging	0,98	neutral	0,11	neutral	4,21	deleterious	-5,09	deleterious	-6,59	high_impact	3,94	neutral	0,85	damaging	0,1	deleterious	3,71	23,3	0,01	0,35	disease	0,93	disease	0,76	disease	0,75	disease	0,69	4	deleterious	0,99	neutral	0,07	deleterious	2	deleterious	0,84	low_impact	-2,34	medium_impact	-0,3	high_impact	2,17	0,36	0,8	NA	NA	N	0,34	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4860	4860	C	T	MI.13582	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	391	131	L	F	Ctc/Ttc	-7,11	0	0	probably_damaging	1	neutral	0,71	neutral	4,58	neutral	-1,72	deleterious	-3,91	medium_impact	2,64	neutral	0,74	damaging	0,04	deleterious	3,97	23,6	0,16	0,45	disease	0,74	neutral	0,48	neutral	0,49	disease	0,58	2	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,42	medium_impact	1,08	0,48	0,8	NA	NA	N	0,19	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4860	4860	C	G	MI.13583	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	391	131	L	V	Ctc/Gtc	-7,11	0	0	probably_damaging	1	neutral	0,5	neutral	4,62	neutral	-0,42	deleterious	-2,93	medium_impact	2,4	neutral	0,7	damaging	0,11	deleterious	3,41	23	0,24	0,45	neutral	0,45	neutral	0,32	neutral	0,4	neutral	0,46	1	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,7	low_impact	-3,54	medium_impact	0,21	medium_impact	0,88	0,46	0,8	NA	NA	N	0,26	N	0,77	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4860	4860	C	A	MI.13584	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	391	131	L	I	Ctc/Atc	-7,11	0	0	probably_damaging	1	neutral	0,4	neutral	4,61	neutral	-0,78	neutral	-1,95	medium_impact	2,35	neutral	0,67	damaging	0,06	deleterious	4,08	23,7	0,23	0,45	disease	0,54	neutral	0,35	neutral	0,42	disease	0,55	1	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	0,11	medium_impact	0,83	0,48	0,8	NA	NA	N	0,28	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4861	4861	T	A	MI.13585	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	392	131	L	H	cTc/cAc	-0,66	0	0	probably_damaging	1	neutral	0,54	neutral	4,57	neutral	-2,22	deleterious	-6,84	medium_impact	3,44	neutral	0,65	damaging	0,05	deleterious	3,99	23,6	0,06	0,35	disease	0,78	disease	0,62	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	0,25	medium_impact	1,75	0,26	0,8	NA	NA	N	0,25	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4861	4861	T	G	MI.13586	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	392	131	L	R	cTc/cGc	-0,66	0	0	probably_damaging	1	neutral	0,35	neutral	4,59	neutral	-1,3	deleterious	-5,86	medium_impact	3,44	neutral	0,61	damaging	0,05	deleterious	4,11	23,7	0,03	0,35	disease	0,74	disease	0,8	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0,06	medium_impact	1,75	0,3	0,8	NA	NA	N	0,26	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4861	4861	T	C	MI.13587	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	392	131	L	P	cTc/cCc	-0,66	0	0	probably_damaging	1	neutral	0,21	neutral	4,57	neutral	-2,35	deleterious	-6,84	medium_impact	3,44	damaging	0,58	damaging	0,04	deleterious	3,86	23,5	0,03	0,35	disease	0,76	disease	0,82	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	-0,11	medium_impact	1,75	0,24	0,8	NA	NA	N	0,26	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4863	4863	A	G	MI.13588	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	394	132	T	A	Aca/Gca	-16,09	0	0	probably_damaging	1	neutral	0,78	neutral	4,69	neutral	-0,04	deleterious	-4,92	high_impact	4,12	neutral	0,72	damaging	0,09	deleterious	3,44	23	0,13	0,4	disease	0,65	neutral	0,5	disease	0,67	disease	0,64	3	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,74	low_impact	-3,54	medium_impact	0,51	high_impact	2,32	0,32	0,8	NA	NA	N	0,26	N	0,69	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4863	4863	A	T	MI.13589	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	394	132	T	S	Aca/Tca	-16,09	0	0	probably_damaging	1	neutral	0,66	neutral	4,57	neutral	-1,41	deleterious	-3,93	medium_impact	2,35	neutral	0,71	damaging	0,12	deleterious	3,21	22,7	0,28	0,45	disease	0,7	disease	0,57	disease	0,64	disease	0,63	3	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,37	medium_impact	0,83	0,65	0,8	NA	NA	N	0,22	N	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9164	9164	T	A	MI.1359	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	638	213	V	D	gTt/gAt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	3,05	deleterious	-9,14	deleterious	-6,21	high_impact	4,5	neutral	0,71	neutral	0,55	deleterious	4,51	24,3	0,08	0,65	NA	NA	disease	0,94	disease	0,81	disease	0,89	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	high_impact	2,76	0,44	0,9	48,23	8,71	P	0,5	N	0,97	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4863	4863	A	C	MI.13590	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	394	132	T	P	Aca/Cca	-16,09	0	0	probably_damaging	1	neutral	0,34	neutral	4,45	deleterious	-4,32	deleterious	-5,9	high_impact	3,78	neutral	0,67	damaging	0,08	deleterious	3,45	23	0,03	0,35	disease	0,9	disease	0,75	disease	0,81	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0,05	high_impact	2,04	0,48	0,8	NA	NA	N	0,33	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4864	4864	C	A	MI.13591	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	395	132	T	K	aCa/aAa	8,55	1	0	probably_damaging	1	neutral	0,65	neutral	4,48	neutral	-2,32	deleterious	-5,9	high_impact	4,12	neutral	0,72	damaging	0,06	deleterious	4,49	24,3	0,04	0,35	disease	0,83	disease	0,77	disease	0,8	disease	0,69	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0,36	high_impact	2,32	0,46	0,8	NA	NA	P	0,64	P	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4864	4864	C	T	MI.13592	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	395	132	T	M	aCa/aTa	8,55	1	0	probably_damaging	1	neutral	0,3	neutral	4,46	neutral	-2,98	deleterious	-5,9	high_impact	3,58	neutral	0,72	damaging	0,06	deleterious	4,03	23,7	0,05	0,35	disease	0,62	disease	0,73	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,74	low_impact	-3,54	medium_impact	0	medium_impact	1,87	0,52	0,8	NA	NA	P	0,62	P	0,92	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4866	4866	T	C	MI.13593	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	397	133	W	R	Tga/Cga	-4,35	0	0	probably_damaging	1	neutral	0,31	neutral	4,58	neutral	-1,97	deleterious	-13,77	high_impact	4,04	neutral	0,68	damaging	0,04	deleterious	3,52	23,1	0,04	0,35	disease	0,78	disease	0,87	disease	0,81	disease	0,71	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	0,02	high_impact	2,26	0,23	0,8	NA	NA	N	0,47	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4866	4866	T	G	MI.13594	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	397	133	W	G	Tga/Gga	-4,35	0	0	probably_damaging	1	neutral	0,35	neutral	4,58	neutral	-2,03	deleterious	-12,79	high_impact	3,69	neutral	0,7	damaging	0,06	deleterious	3,9	23,5	0,06	0,35	disease	0,77	disease	0,76	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,06	medium_impact	1,96	0,17	0,8	NA	NA	N	0,41	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4867	4867	G	T	MI.13595	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	398	133	W	L	tGa/tTa	2,33	0,99	0	probably_damaging	1	neutral	0,94	neutral	4,83	neutral	1,72	deleterious	-12,79	medium_impact	2,39	neutral	0,77	damaging	0,1	deleterious	4,19	23,8	0,07	0,35	disease	0,77	disease	0,74	disease	0,72	neutral	0,47	1	deleterious	1	deleterious	0,47	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,87	medium_impact	0,87	0,17	0,8	NA	NA	N	0,38	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4867	4867	G	C	MI.13596	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	398	133	W	S	tGa/tCa	2,33	0,99	0	probably_damaging	1	neutral	0,48	neutral	4,6	neutral	-1,01	deleterious	-13,77	high_impact	4,04	neutral	0,7	damaging	0,05	deleterious	3,95	23,6	0,06	0,35	disease	0,65	disease	0,81	disease	0,76	disease	0,7	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	0,19	high_impact	2,26	0,17	0,8	NA	NA	N	0,52	P	0,94	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4868	4868	A	T	MI.13597	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	399	133	W	C	tgA/tgT	5,78	1	0	probably_damaging	1	neutral	0,22	neutral	4,57	neutral	-2,34	deleterious	-12,79	high_impact	3,69	neutral	0,67	damaging	0,04	deleterious	4,05	23,7	0,05	0,35	disease	0,97	disease	0,83	disease	0,81	disease	0,75	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,1	medium_impact	1,96	0,26	0,8	NA	NA	P	0,63	P	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4868	4868	A	C	MI.13598	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	399	133	W	C	tgA/tgC	5,78	1	0	probably_damaging	1	neutral	0,22	neutral	4,57	neutral	-2,34	deleterious	-12,79	high_impact	3,69	neutral	0,67	damaging	0,04	deleterious	3,96	23,6	0,05	0,35	disease	0,97	disease	0,83	disease	0,81	disease	0,75	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,1	medium_impact	1,96	0,26	0,8	NA	NA	P	0,62	P	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4869	4869	C	A	MI.13599	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	400	134	Q	K	Caa/Aaa	2,1	1	0	probably_damaging	0,99	neutral	0,37	neutral	4,57	neutral	-1,65	deleterious	-3,93	high_impact	4,1	neutral	0,84	damaging	0,1	deleterious	3,87	23,5	0,11	0,4	neutral	0,47	disease	0,84	disease	0,74	disease	0,71	4	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,79	low_impact	-2,62	medium_impact	0,08	high_impact	2,31	0,33	0,8	NA	NA	N	0,51	P	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8590	8590	C	G	MI.136	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	64	22	L	V	Ctg/Gtg	-15,14	0	0	benign	0,32	neutral	0,14	neutral	4,22	neutral	-1,26	neutral	-1,09	low_impact	1,14	neutral	0,9	neutral	0,81	deleterious	0,35	6,17	0,31	0,65	neutral	0,42	neutral	0,34	neutral	0,37	neutral	0,46	1	neutral	0,83	neutral	0,41	neutral	-6	neutral	0,36	medium_impact	-0,45	medium_impact	-0,15	medium_impact	-0,12	0,59	0,9	25,22	20,33	N	0,49	N	0,23	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9164	9164	T	C	MI.1360	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	638	213	V	A	gTt/gCt	6,14	1	0	probably_damaging	0,99	deleterious	0	neutral	3,07	deleterious	-5,96	deleterious	-3,54	high_impact	4,5	neutral	0,69	neutral	0,64	deleterious	3,53	23,1	0,15	0,65	NA	NA	disease	0,74	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,65	low_impact	-1,4	high_impact	2,76	0,27	0,9	48,23	8,71	P	0,51	P	0,6	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4869	4869	C	G	MI.13600	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	400	134	Q	E	Caa/Gaa	2,1	1	0	probably_damaging	0,99	neutral	0,33	neutral	4,57	neutral	-1,82	deleterious	-2,95	high_impact	4,1	neutral	0,87	damaging	0,11	deleterious	3,02	22,3	0,22	0,45	disease	0,65	disease	0,79	disease	0,72	disease	0,68	4	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,81	low_impact	-2,62	medium_impact	0,04	high_impact	2,31	0,46	0,8	NA	NA	N	0,49	N	0,9	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4870	4870	A	G	MI.13601	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	401	134	Q	R	cAa/cGa	2,79	1	0	probably_damaging	0,99	neutral	0,37	neutral	4,57	neutral	-1,93	deleterious	-3,93	high_impact	4,1	neutral	0,83	damaging	0,11	deleterious	3,16	22,6	0,15	0,4	disease	0,55	disease	0,86	disease	0,76	disease	0,71	4	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-2,62	medium_impact	0,08	high_impact	2,31	0,14	0,8	NA	NA	P	0,57	P	0,87	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4870	4870	A	C	MI.13602	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	401	134	Q	P	cAa/cCa	2,79	1	0	probably_damaging	1	neutral	0,24	neutral	4,61	neutral	-0,58	deleterious	-5,9	high_impact	3,75	neutral	0,83	damaging	0,1	deleterious	3,06	22,4	0,04	0,35	disease	0,79	disease	0,91	disease	0,79	disease	0,69	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	-0,07	high_impact	2,01	0,2	0,8	NA	NA	N	0,53	P	0,96	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4870	4870	A	T	MI.13603	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	401	134	Q	L	cAa/cTa	2,79	1	0	probably_damaging	1	neutral	0,69	neutral	5,05	neutral	2,47	deleterious	-6,88	medium_impact	3,29	neutral	0,87	damaging	0,12	deleterious	3,5	23,1	0,07	0,35	disease	0,82	disease	0,88	disease	0,63	disease	0,6	2	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0,4	medium_impact	1,63	0,13	0,8	NA	NA	N	0,41	N	0,96	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4871	4871	A	C	MI.13604	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	402	134	Q	H	caA/caC	5,32	1	0	probably_damaging	1	neutral	0,54	neutral	4,56	neutral	-2,63	deleterious	-4,92	high_impact	4,1	neutral	0,85	damaging	0,09	deleterious	3,34	22,9	0,15	0,4	neutral	0,44	disease	0,78	disease	0,75	disease	0,68	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,25	high_impact	2,31	0,5	0,8	NA	NA	P	0,57	P	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4871	4871	A	T	MI.13605	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	402	134	Q	H	caA/caT	5,32	1	0	probably_damaging	1	neutral	0,54	neutral	4,56	neutral	-2,63	deleterious	-4,92	high_impact	4,1	neutral	0,85	damaging	0,09	deleterious	3,47	23	0,15	0,4	neutral	0,44	disease	0,78	disease	0,75	disease	0,68	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,25	high_impact	2,31	0,5	0,8	NA	NA	P	0,57	P	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4872	4872	A	G	MI.13606	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	403	135	K	E	Aaa/Gaa	4,63	1	0	probably_damaging	1	neutral	0,38	neutral	4,35	deleterious	-4,32	deleterious	-3,93	high_impact	3,82	neutral	0,84	neutral	0,39	deleterious	3,71	23,3	0,08	0,35	disease	0,52	disease	0,85	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	0,09	high_impact	2,07	0,33	0,8	NA	NA	P	0,63	P	0,91	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4872	4872	A	C	MI.13607	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	403	135	K	Q	Aaa/Caa	4,63	1	0	probably_damaging	1	neutral	0,36	neutral	4,34	deleterious	-4,44	deleterious	-3,93	high_impact	4,17	neutral	0,84	neutral	0,44	deleterious	3,21	22,7	0,13	0,4	disease	0,65	disease	0,79	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	0,07	high_impact	2,37	0,35	0,8	NA	NA	P	0,64	P	0,88	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4873	4873	A	C	MI.13608	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	404	135	K	T	aAa/aCa	8,55	1	0	probably_damaging	1	neutral	0,46	neutral	4,37	deleterious	-3,21	deleterious	-5,9	high_impact	3,82	neutral	0,83	neutral	0,41	deleterious	3,49	23,1	0,07	0,35	disease	0,52	disease	0,8	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	0,17	high_impact	2,07	0,2	0,8	NA	NA	P	0,62	P	0,81	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4873	4873	A	T	MI.13609	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	404	135	K	M	aAa/aTa	8,55	1	0	probably_damaging	1	neutral	0,24	neutral	4,36	deleterious	-3,44	deleterious	-5,9	high_impact	4,17	neutral	0,92	neutral	0,54	deleterious	3,71	23,3	0,06	0,35	disease	0,59	disease	0,83	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,76	low_impact	-3,54	medium_impact	-0,07	high_impact	2,37	0,2	0,8	NA	NA	P	0,68	P	0,45	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9164	9164	T	G	MI.1361	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	638	213	V	G	gTt/gGt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	3,05	deleterious	-8,56	deleterious	-6,23	high_impact	4,5	neutral	0,68	neutral	0,66	deleterious	3,86	23,5	0,11	0,65	NA	NA	disease	0,9	disease	0,73	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,76	0,33	0,9	48,23	8,71	N	0,45	N	0,93	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4874	4874	A	T	MI.13610	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	405	135	K	N	aaA/aaT	8,55	1	0	probably_damaging	1	neutral	0,36	neutral	4,34	deleterious	-4,63	deleterious	-4,92	high_impact	4,17	neutral	0,81	neutral	0,36	deleterious	3,8	23,4	0,14	0,4	disease	0,61	disease	0,81	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	0,07	high_impact	2,37	0,21	0,8	NA	NA	P	0,64	P	0,69	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4874	4874	A	C	MI.13611	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	405	135	K	N	aaA/aaC	8,55	1	0	probably_damaging	1	neutral	0,36	neutral	4,34	deleterious	-4,63	deleterious	-4,92	high_impact	4,17	neutral	0,81	neutral	0,36	deleterious	3,75	23,3	0,14	0,4	disease	0,61	disease	0,81	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	0,07	high_impact	2,37	0,21	0,8	NA	NA	P	0,64	P	0,69	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4875	4875	C	A	MI.13612	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	406	136	L	M	Cta/Ata	4,63	1	0	probably_damaging	1	neutral	0,32	neutral	4,54	neutral	-1,57	neutral	-1,6	medium_impact	2,02	neutral	0,93	damaging	0,26	deleterious	3,84	23,4	0,35	0,5	disease	0,83	disease	0,57	neutral	0,49	disease	0,52	0	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,03	medium_impact	0,56	0,64	0,8	NA	NA	P	0,57	P	0,18	polymorphism	0,96	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4875	4875	C	G	MI.13613	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	406	136	L	V	Cta/Gta	4,63	1	0	probably_damaging	1	neutral	0,45	neutral	4,69	neutral	0,16	neutral	-1,51	low_impact	1,57	neutral	0,93	neutral	0,47	deleterious	2,25	17,87	0,31	0,45	disease	0,68	disease	0,59	neutral	0,49	neutral	0,35	3	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	0,16	medium_impact	0,18	0,44	0,8	NA	NA	N	0,52	P	0,42	polymorphism	0,97	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4876	4876	T	G	MI.13614	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	407	136	L	R	cTa/cGa	-1,58	0	0	probably_damaging	1	neutral	0,27	neutral	4,53	deleterious	-3,94	deleterious	-5,53	medium_impact	3,26	neutral	0,81	damaging	0,12	deleterious	4,2	23,9	0,04	0,35	disease	0,59	disease	0,9	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,03	medium_impact	1,6	0,15	0,8	NA	NA	N	0,28	N	0,92	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4876	4876	T	C	MI.13615	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	407	136	L	P	cTa/cCa	-1,58	0	0	probably_damaging	1	neutral	0,29	neutral	4,52	deleterious	-4,51	deleterious	-6,16	medium_impact	3,26	neutral	0,91	damaging	0,14	deleterious	3,92	23,5	0,04	0,35	disease	0,58	disease	0,88	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,6	0,18	0,8	NA	NA	N	0,38	N	0,91	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4876	4876	T	A	MI.13616	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	407	136	L	Q	cTa/cAa	-1,58	0	0	probably_damaging	1	neutral	0,26	neutral	4,53	deleterious	-4,08	deleterious	-5,53	medium_impact	3,26	neutral	0,86	damaging	0,15	deleterious	4,37	24,1	0,06	0,35	neutral	0,41	disease	0,77	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	-0,04	medium_impact	1,6	0,17	0,8	NA	NA	N	0,31	N	0,89	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4878	4878	G	T	MI.13617	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	409	137	A	S	Gcc/Tcc	-2,5	0	0	probably_damaging	1	neutral	0,5	neutral	4,23	deleterious	-3,18	deleterious	-2,95	medium_impact	2,64	neutral	0,87	damaging	0,11	deleterious	2,05	16,51	0,15	0,4	disease	0,65	disease	0,78	disease	0,61	disease	0,64	3	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,21	medium_impact	1,08	0,64	0,8	0,29	6,87	N	0,26	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4878	4878	G	A	MI.13618	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	409	137	A	T	Gcc/Acc	-2,5	0	0	probably_damaging	1	neutral	0,47	neutral	4,25	deleterious	-4,12	deleterious	-3,93	medium_impact	2,75	neutral	0,86	damaging	0,1	deleterious	3,88	23,5	0,09	0,4	disease	0,59	disease	0,76	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,18	medium_impact	1,17	0,68	0,85	0,29	6,87	N	0,29	N	0,86	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4878	4878	G	C	MI.13619	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	409	137	A	P	Gcc/Ccc	-2,5	0	0	probably_damaging	1	neutral	0,4	neutral	4,19	deleterious	-6,01	deleterious	-4,92	low_impact	1,76	neutral	0,81	damaging	0,24	deleterious	1,82	15,09	0,03	0,35	disease	0,52	neutral	0,39	disease	0,6	neutral	0,48	0	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	0,11	medium_impact	0,34	0,63	0,8	0,29	6,87	N	0,29	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9166	9166	T	A	MI.1362	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	640	214	F	I	Ttc/Atc	-12,37	0	0	probably_damaging	0,99	neutral	0,07	neutral	2,2	deleterious	-6,85	deleterious	-5,23	high_impact	3,65	neutral	0,63	neutral	0,73	deleterious	4,48	24,2	0,14	0,65	NA	NA	disease	0,86	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,87	low_impact	-2,65	medium_impact	-0,34	high_impact	2,03	0,41	0,9	49,56	8,9	N	0,4	N	0,94	disease_causing	0,54	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4879	4879	C	T	MI.13620	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	410	137	A	V	gCc/gTc	5,78	1	0	probably_damaging	1	neutral	0,54	neutral	4,31	deleterious	-3,32	deleterious	-3,93	medium_impact	3,19	neutral	0,9	damaging	0,12	deleterious	4,09	23,7	0,08	0,35	disease	0,82	disease	0,82	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	0,25	medium_impact	1,54	0,68	0,85	0,29	6,87	P	0,57	P	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4879	4879	C	G	MI.13621	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	410	137	A	G	gCc/gGc	5,78	1	0	probably_damaging	1	neutral	0,36	neutral	4,19	neutral	-2,17	deleterious	-3,93	medium_impact	2,43	neutral	0,89	damaging	0,14	deleterious	3,53	23,1	0,13	0,4	disease	0,81	disease	0,76	disease	0,56	disease	0,61	2	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,07	medium_impact	0,9	0,75	0,85	0,29	6,87	P	0,59	P	0,81	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4879	4879	C	A	MI.13622	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	410	137	A	D	gCc/gAc	5,78	1	0	probably_damaging	1	neutral	0,21	neutral	4,18	deleterious	-5,74	deleterious	-5,9	high_impact	3,65	neutral	0,83	damaging	0,08	deleterious	4,43	24,2	0,02	0,35	disease	0,75	disease	0,92	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,11	medium_impact	1,93	0,31	0,8	0,29	6,87	P	0,6	P	0,95	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4881	4881	C	T	MI.13623	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	412	138	P	S	Ccc/Tcc	-5,73	0	0	probably_damaging	1	neutral	0,42	neutral	4,55	neutral	-1,12	deleterious	-7,86	high_impact	3,81	neutral	0,91	damaging	0,12	deleterious	3,89	23,5	0,07	0,35	neutral	0,42	disease	0,77	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,13	high_impact	2,06	0,15	0,8	NA	NA	N	0,37	N	0,72	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4881	4881	C	A	MI.13624	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	412	138	P	T	Ccc/Acc	-5,73	0	0	probably_damaging	1	neutral	0,4	neutral	4,51	neutral	-1,87	deleterious	-7,86	high_impact	3,81	neutral	0,81	damaging	0,08	deleterious	3,69	23,3	0,07	0,35	disease	0,65	disease	0,77	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	0,11	high_impact	2,06	0,56	0,8	NA	NA	N	0,31	N	0,88	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4881	4881	C	G	MI.13625	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	412	138	P	A	Ccc/Gcc	-5,73	0	0	probably_damaging	1	neutral	0,51	neutral	4,61	neutral	-0,32	deleterious	-7,86	medium_impact	3,46	neutral	0,82	damaging	0,13	deleterious	3,08	22,5	0,09	0,35	neutral	0,44	disease	0,62	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,22	medium_impact	1,77	0,62	0,8	NA	NA	N	0,28	N	0,72	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4882	4882	C	G	MI.13626	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	413	138	P	R	cCc/cGc	5,55	1	0	probably_damaging	1	neutral	0,35	neutral	4,5	neutral	-2,41	deleterious	-8,85	high_impact	4,16	neutral	0,83	damaging	0,08	deleterious	3,58	23,2	0,03	0,35	neutral	0,39	disease	0,87	disease	0,79	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	0,06	high_impact	2,36	0,42	0,8	NA	NA	P	0,64	P	0,56	polymorphism	0,99	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4882	4882	C	A	MI.13627	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	413	138	P	H	cCc/cAc	5,55	1	0	probably_damaging	1	neutral	0,53	neutral	4,48	deleterious	-3,44	deleterious	-8,85	high_impact	4,16	neutral	0,91	damaging	0,09	deleterious	4,01	23,6	0,04	0,35	disease	0,8	disease	0,83	disease	0,79	disease	0,68	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,24	high_impact	2,36	0,35	0,8	NA	NA	P	0,64	P	0,71	polymorphism	0,99	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4882	4882	C	T	MI.13628	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	413	138	P	L	cCc/cTc	5,55	1	0	probably_damaging	1	neutral	0,71	neutral	4,5	neutral	-2,31	deleterious	-9,83	high_impact	3,6	neutral	0,74	damaging	0,08	deleterious	4,39	24,1	0,04	0,35	disease	0,58	disease	0,85	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	0,42	medium_impact	1,89	0,59	0,8	NA	NA	N	0,5	N	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4884	4884	A	T	MI.13629	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	415	139	I	F	Atc/Ttc	-7,8	0	0	benign	0,2	neutral	0,87	neutral	4,53	neutral	0,41	deleterious	-2,58	neutral_impact	-0,1	neutral	0,87	neutral	0,74	deleterious	0,85	9,76	0,17	0,45	disease	0,67	neutral	0,41	neutral	0,25	disease	0,63	3	neutral	0,1	deleterious	0,84	neutral	-6	neutral	0,26	medium_impact	-0,25	medium_impact	0,67	low_impact	-1,23	0,63	0,8	NA	NA	N	0,25	N	0,44	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9166	9166	T	C	MI.1363	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	640	214	F	L	Ttc/Ctc	-12,37	0	0	probably_damaging	0,98	deleterious	0,03	neutral	2,24	deleterious	-6,92	deleterious	-5,2	high_impact	3,58	damaging	0,54	neutral	0,64	deleterious	4,11	23,7	0,19	0,65	NA	NA	disease	0,87	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,85	low_impact	-2,36	medium_impact	-0,56	medium_impact	1,97	0,48	0,9	49,56	8,9	N	0,4	N	0,89	disease_causing	0,57	0,38	rs1057516063	Likely pathogenic	Optic_neuropathy	RCV000408929.1	Human_Phenotype_Ontology:MedGen	.	.	.	.	.	.	.	.	.	.
chrM	4884	4884	A	C	MI.13630	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	415	139	I	L	Atc/Ctc	-7,8	0	0	benign	0	neutral	1	neutral	4,82	neutral	-0,05	neutral	0,4	neutral_impact	-1,21	neutral	0,9	neutral	0,95	neutral	-0,84	0,04	0,27	0,45	neutral	0,37	neutral	0,19	neutral	0,19	neutral	0,35	3	neutral	0	deleterious	1	neutral	-6	neutral	0,12	medium_impact	1,95	high_impact	1,87	low_impact	-2,16	0,64	0,8	NA	NA	N	0,38	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4884	4884	A	G	MI.13631	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	415	139	I	V	Atc/Gtc	-7,8	0	0	benign	0,05	neutral	0,34	neutral	4,65	neutral	0,05	neutral	-0,89	low_impact	1,24	neutral	0,95	neutral	0,8	neutral	1,07	11,05	0,46	0,55	neutral	0,38	neutral	0,25	neutral	0,31	neutral	0,46	1	neutral	0,63	deleterious	0,65	neutral	-6	neutral	0,13	medium_impact	0,37	medium_impact	0,05	medium_impact	-0,1	0,49	0,8	NA	NA	N	0,42	N	0,63	polymorphism	1	0,02	rs879155022	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4885	4885	T	G	MI.13632	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	416	139	I	S	aTc/aGc	-3,65	0	0	benign	0,13	neutral	0,41	neutral	4,48	neutral	-2,88	deleterious	-4,48	low_impact	1,94	neutral	0,87	neutral	0,53	deleterious	2,35	18,51	0,03	0,35	neutral	0,36	disease	0,64	disease	0,53	disease	0,61	2	neutral	0,52	deleterious	0,64	neutral	-6	neutral	0,21	medium_impact	-0,04	medium_impact	0,12	medium_impact	0,49	0,28	0,8	NA	NA	N	0,34	N	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4885	4885	T	C	MI.13633	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	416	139	I	T	aTc/aCc	-3,65	0	0	benign	0,01	neutral	0,33	neutral	4,52	neutral	-2,31	deleterious	-3,59	neutral_impact	0,19	neutral	0,92	neutral	0,95	deleterious	0,16	4,23	0,07	0,35	disease	0,67	neutral	0,33	neutral	0,33	disease	0,62	2	neutral	0,66	deleterious	0,66	neutral	-6	neutral	0,18	medium_impact	1,03	medium_impact	0,04	medium_impact	-0,98	0,35	0,8	NA	NA	N	0,42	N	0,65	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4885	4885	T	A	MI.13634	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	416	139	I	N	aTc/aAc	-3,65	0	0	benign	0,36	neutral	0,13	neutral	4,46	deleterious	-4,13	deleterious	-5,46	medium_impact	2,28	neutral	0,9	neutral	0,46	deleterious	2,5	19,46	0,09	0,35	disease	0,65	disease	0,69	disease	0,55	disease	0,66	3	neutral	0,85	neutral	0,39	neutral	-3	neutral	0,36	medium_impact	-0,57	medium_impact	-0,25	medium_impact	0,78	0,33	0,8	NA	NA	N	0,42	N	0,86	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4886	4886	C	G	MI.13635	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	417	139	I	M	atC/atG	4,63	0,66	0	benign	0,01	neutral	0,43	neutral	4,53	neutral	-2,11	neutral	-0,74	neutral_impact	-0,64	neutral	0,94	neutral	0,94	neutral	-0,27	0,78	0,28	0,45	disease	0,59	neutral	0,1	neutral	0,17	neutral	0,29	4	neutral	0,56	deleterious	0,71	neutral	-6	neutral	0,14	medium_impact	1,03	medium_impact	0,14	low_impact	-1,68	0,52	0,8	NA	NA	N	0,45	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4886	4886	C	A	MI.13636	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	417	139	I	M	atC/atA	4,63	0,66	0	benign	0,01	neutral	0,43	neutral	4,53	neutral	-2,11	neutral	-0,74	neutral_impact	-0,64	neutral	0,94	neutral	0,94	deleterious	0,15	4,11	0,28	0,45	disease	0,59	neutral	0,1	neutral	0,17	neutral	0,29	4	neutral	0,56	deleterious	0,71	neutral	-6	neutral	0,14	medium_impact	1,03	medium_impact	0,14	low_impact	-1,68	0,52	0,8	NA	NA	N	0,46	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4887	4887	T	G	MI.13637	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	418	140	S	A	Tca/Gca	-9,87	0	0	possibly_damaging	0,51	neutral	0,69	neutral	4,71	neutral	0,87	deleterious	-2,54	neutral_impact	0,71	neutral	0,87	neutral	0,94	deleterious	2,35	18,48	0,24	0,45	neutral	0,41	neutral	0,12	neutral	0,31	neutral	0,25	5	neutral	0,41	deleterious	0,59	neutral	-3	deleterious	0,56	medium_impact	-0,81	medium_impact	0,4	medium_impact	-0,55	0,54	0,8	2,02	7,8	N	0,34	N	0,28	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4887	4887	T	A	MI.13638	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	418	140	S	T	Tca/Aca	-9,87	0	0	possibly_damaging	0,7	neutral	0,49	neutral	4,62	neutral	-0,55	neutral	-2,22	neutral_impact	0,73	neutral	0,88	neutral	0,97	deleterious	2,52	19,58	0,25	0,45	neutral	0,43	neutral	0,13	neutral	0,32	neutral	0,27	5	neutral	0,67	neutral	0,4	neutral	-3	deleterious	0,62	low_impact	-1,13	medium_impact	0,2	medium_impact	-0,53	0,52	0,8	2,02	7,8	N	0,4	N	0,57	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4887	4887	T	C	MI.13639	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	418	140	S	P	Tca/Cca	-9,87	0	0	probably_damaging	0,95	neutral	0,22	neutral	4,58	neutral	-2,46	deleterious	-4,46	medium_impact	3,21	neutral	0,75	neutral	0,35	deleterious	3,95	23,6	0,05	0,35	disease	0,84	disease	0,87	disease	0,73	disease	0,69	4	neutral	0,96	neutral	0,14	deleterious	1	deleterious	0,87	low_impact	-1,97	medium_impact	-0,1	medium_impact	1,56	0,37	0,8	2,02	7,8	N	0,32	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9166	9166	T	G	MI.1364	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	640	214	F	V	Ttc/Gtc	-12,37	0	0	probably_damaging	0,99	deleterious	0,03	neutral	2,24	deleterious	-7,94	deleterious	-6,12	high_impact	4,2	damaging	0,52	neutral	0,63	deleterious	4,17	23,8	0,16	0,65	NA	NA	disease	0,9	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,87	low_impact	-2,65	medium_impact	-0,56	high_impact	2,5	0,33	0,9	49,56	8,9	N	0,42	N	0,99	disease_causing	0,72	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4888	4888	C	G	MI.13640	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	419	140	S	W	tCa/tGa	-0,2	0	0	probably_damaging	0,96	neutral	0,19	neutral	4,6	neutral	-1,25	deleterious	-6,18	medium_impact	2,4	neutral	0,88	neutral	0,41	deleterious	4,32	24	0,05	0,35	disease	0,88	disease	0,85	disease	0,66	disease	0,66	3	neutral	0,98	neutral	0,12	deleterious	1	deleterious	0,83	low_impact	-2,06	medium_impact	-0,14	medium_impact	0,88	0,18	0,8	2,02	7,8	N	0,36	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4888	4888	C	T	MI.13641	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	419	140	S	L	tCa/tTa	-0,2	0	0	benign	0,03	neutral	0,87	neutral	4,67	neutral	0,45	deleterious	-5,04	low_impact	1,43	neutral	0,93	neutral	0,52	deleterious	4,58	24,4	0,08	0,35	disease	0,67	disease	0,75	disease	0,6	disease	0,66	3	neutral	0,06	deleterious	0,92	neutral	-6	neutral	0,27	medium_impact	0,59	medium_impact	0,67	medium_impact	0,06	0,4	0,8	2,02	7,8	N	0,23	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4890	4890	A	G	MI.13642	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	421	141	I	V	Atc/Gtc	-8,95	0	0	probably_damaging	0,99	neutral	0,28	neutral	4,6	neutral	0,26	neutral	-0,46	low_impact	0,96	neutral	0,91	neutral	0,9	neutral	1,55	13,6	0,52	0,6	disease	0,51	neutral	0,26	neutral	0,44	neutral	0,31	4	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,67	low_impact	-2,62	medium_impact	-0,02	medium_impact	-0,34	0,49	0,8	NA	NA	N	0,47	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4890	4890	A	C	MI.13643	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	421	141	I	L	Atc/Ctc	-8,95	0	0	probably_damaging	0,99	neutral	1	neutral	4,87	neutral	1,06	neutral	-1,82	neutral_impact	-0,53	neutral	0,86	neutral	0,95	deleterious	2,25	17,82	0,24	0,45	disease	0,56	neutral	0,13	neutral	0,33	neutral	0,26	5	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,66	low_impact	-2,62	high_impact	1,87	low_impact	-1,59	0,59	0,8	NA	NA	N	0,29	N	0,6	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4890	4890	A	T	MI.13644	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	421	141	I	F	Atc/Ttc	-8,95	0	0	probably_damaging	1	neutral	0,27	neutral	4,5	neutral	-0,81	deleterious	-3,83	medium_impact	1,97	neutral	0,85	neutral	0,45	deleterious	3,85	23,4	0,12	0,4	disease	0,75	disease	0,72	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,03	medium_impact	0,51	0,44	0,8	NA	NA	N	0,3	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4891	4891	T	A	MI.13645	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	422	141	I	N	aTc/aAc	-1,12	0	0	probably_damaging	1	neutral	0,1	neutral	4,55	deleterious	-3,78	deleterious	-6,49	medium_impact	3,06	neutral	0,88	neutral	0,39	deleterious	4,54	24,3	0,06	0,35	disease	0,77	disease	0,8	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,32	medium_impact	1,43	0,38	0,8	NA	NA	N	0,38	N	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4891	4891	T	C	MI.13646	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	422	141	I	T	aTc/aCc	-1,12	0	0	probably_damaging	1	neutral	0,11	neutral	4,51	neutral	-1,96	deleterious	-4,3	medium_impact	2,37	neutral	0,89	neutral	0,44	deleterious	3,44	23	0,06	0,35	disease	0,71	disease	0,61	disease	0,61	disease	0,68	4	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,3	medium_impact	0,85	0,28	0,8	NA	NA	N	0,47	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4891	4891	T	G	MI.13647	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	422	141	I	S	aTc/aGc	-1,12	0	0	probably_damaging	1	neutral	0,33	neutral	4,5	neutral	-2,72	deleterious	-5,51	medium_impact	2,71	neutral	0,84	neutral	0,43	deleterious	4,25	23,9	0,03	0,35	neutral	0,48	disease	0,76	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,04	medium_impact	1,14	0,31	0,8	NA	NA	N	0,26	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4892	4892	C	A	MI.13648	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	423	141	I	M	atC/atA	5,78	0,87	0	probably_damaging	1	neutral	0,11	neutral	4,53	neutral	-1,3	deleterious	-2,54	low_impact	1,2	neutral	0,9	neutral	0,64	deleterious	3,84	23,4	0,23	0,45	disease	0,79	neutral	0,49	disease	0,56	disease	0,64	3	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	-0,3	medium_impact	-0,13	0,57	0,8	NA	NA	P	0,57	P	0,67	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4892	4892	C	G	MI.13649	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	423	141	I	M	atC/atG	5,78	0,87	0	probably_damaging	1	neutral	0,11	neutral	4,53	neutral	-1,3	deleterious	-2,54	low_impact	1,2	neutral	0,9	neutral	0,64	deleterious	3,34	22,9	0,23	0,45	disease	0,79	neutral	0,49	disease	0,56	disease	0,64	3	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	-0,3	medium_impact	-0,13	0,57	0,8	NA	NA	P	0,57	P	0,67	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9167	9167	T	C	MI.1365	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	641	214	F	S	tTc/tCc	5,68	1	0	probably_damaging	0,99	deleterious	0	neutral	2,16	deleterious	-7,73	deleterious	-7,04	high_impact	4,2	damaging	0,5	neutral	0,8	deleterious	4,36	24,1	0,14	0,65	NA	NA	disease	0,89	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,65	low_impact	-1,4	high_impact	2,5	0,28	0,9	49,56	8,9	N	0,47	N	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4893	4893	A	C	MI.13650	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	424	142	M	L	Ata/Cta	-9,87	0	0	benign	0,18	neutral	1	neutral	5,27	neutral	2,7	neutral	0,54	neutral_impact	-1,24	neutral	0,88	neutral	0,97	deleterious	0,49	7,33	0,18	0,45	disease	0,52	neutral	0,2	neutral	0,44	neutral	0,25	5	neutral	0,18	deleterious	0,91	neutral	-6	neutral	0,35	medium_impact	-0,19	high_impact	1,87	low_impact	-2,19	0,34	0,8	0,29	8,23	N	0,33	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4893	4893	A	T	MI.13651	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	424	142	M	L	Ata/Tta	-9,87	0	0	benign	0,18	neutral	1	neutral	5,27	neutral	2,7	neutral	0,54	neutral_impact	-1,24	neutral	0,88	neutral	0,97	deleterious	0,56	7,85	0,18	0,45	disease	0,52	neutral	0,2	neutral	0,44	neutral	0,25	5	neutral	0,18	deleterious	0,91	neutral	-6	neutral	0,35	medium_impact	-0,19	high_impact	1,87	low_impact	-2,19	0,34	0,8	0,29	8,23	N	0,33	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4893	4893	A	G	MI.13652	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	424	142	M	V	Ata/Gta	-9,87	0	0	benign	0,25	neutral	0,34	neutral	4,64	neutral	-0,01	neutral	-1,64	low_impact	1,38	neutral	0,84	damaging	0,24	deleterious	2,69	20,8	0,14	0,4	neutral	0,49	disease	0,62	disease	0,62	disease	0,7	4	neutral	0,59	deleterious	0,55	neutral	-6	deleterious	0,49	medium_impact	-0,36	medium_impact	0,05	medium_impact	0,02	0,41	0,8	0,29	8,23	N	0,27	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4894	4894	T	C	MI.13653	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	425	142	M	T	aTa/aCa	-1,35	0	0	possibly_damaging	0,74	neutral	0,3	neutral	4,52	neutral	-2,45	deleterious	-3,65	low_impact	1,29	neutral	0,89	damaging	0,27	deleterious	2,92	21,9	0,05	0,35	neutral	0,4	disease	0,62	disease	0,68	disease	0,71	4	neutral	0,8	neutral	0,28	neutral	-3	deleterious	0,7	low_impact	-1,21	medium_impact	0	medium_impact	-0,06	0,26	0,8	0,29	8,23	N	0,36	N	0,8	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4894	4894	T	A	MI.13654	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	425	142	M	K	aTa/aAa	-1,35	0	0	probably_damaging	0,91	neutral	0,39	neutral	4,5	deleterious	-3,86	deleterious	-4,41	medium_impact	2,23	neutral	0,82	damaging	0,19	deleterious	3,93	23,5	0,02	0,35	disease	0,71	disease	0,76	disease	0,75	disease	0,72	4	neutral	0,91	neutral	0,24	deleterious	1	deleterious	0,83	low_impact	-1,72	medium_impact	0,1	medium_impact	0,73	0,22	0,8	0,29	8,23	N	0,26	N	0,93	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4895	4895	A	T	MI.13655	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	426	142	M	I	atA/atT	7,4	0,95	0,04	benign	0,07	neutral	0,47	neutral	4,73	neutral	0,66	neutral	-0,95	neutral_impact	0,26	neutral	0,87	neutral	0,52	deleterious	2,22	17,61	0,17	0,45	disease	0,53	neutral	0,38	neutral	0,48	neutral	0,38	2	neutral	0,47	deleterious	0,7	neutral	-6	neutral	0,29	medium_impact	0,23	medium_impact	0,18	medium_impact	-0,93	0,48	0,8	0,29	8,23	N	0,56	P	0,49	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4895	4895	A	C	MI.13656	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	426	142	M	I	atA/atC	7,4	0,95	0,04	benign	0,07	neutral	0,47	neutral	4,73	neutral	0,66	neutral	-0,95	neutral_impact	0,26	neutral	0,87	neutral	0,52	deleterious	2,12	16,95	0,17	0,45	disease	0,53	neutral	0,38	neutral	0,48	neutral	0,38	2	neutral	0,47	deleterious	0,7	neutral	-6	neutral	0,29	medium_impact	0,23	medium_impact	0,18	medium_impact	-0,93	0,48	0,8	0,29	8,23	N	0,55	P	0,49	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4896	4896	T	A	MI.13657	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	427	143	Y	N	Tac/Aac	-4,81	0	0	possibly_damaging	0,9	neutral	0,17	neutral	4,62	neutral	-2,97	deleterious	-6,89	medium_impact	2	neutral	0,86	damaging	0,16	deleterious	3,96	23,6	0,06	0,35	disease	0,7	disease	0,67	disease	0,61	disease	0,68	4	neutral	0,94	neutral	0,14	NA	0	deleterious	0,76	low_impact	-1,67	medium_impact	-0,17	medium_impact	0,54	0,37	0,8	1,73	6,88	N	0,3	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4896	4896	T	G	MI.13658	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	427	143	Y	D	Tac/Gac	-4,81	0	0	possibly_damaging	0,87	neutral	0,09	neutral	4,56	deleterious	-4,28	deleterious	-7,8	medium_impact	3,04	neutral	0,85	damaging	0,11	deleterious	3,89	23,5	0,04	0,35	disease	0,9	disease	0,78	disease	0,71	disease	0,69	4	neutral	0,96	neutral	0,11	NA	0	deleterious	0,81	low_impact	-1,55	medium_impact	-0,35	medium_impact	1,42	0,29	0,8	1,73	6,88	N	0,32	N	0,97	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4896	4896	T	C	MI.13659	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	427	143	Y	H	Tac/Cac	-4,81	0	0	possibly_damaging	0,9	neutral	0,27	neutral	4,57	neutral	-2,95	deleterious	-3,92	medium_impact	2,85	neutral	0,9	damaging	0,23	deleterious	3,51	23,1	0,12	0,4	disease	0,83	disease	0,63	disease	0,64	disease	0,67	3	neutral	0,92	neutral	0,19	NA	0	deleterious	0,79	low_impact	-1,67	medium_impact	-0,03	medium_impact	1,26	0,33	0,8	1,73	6,88	N	0,43	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9167	9167	T	A	MI.1366	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	641	214	F	Y	tTc/tAc	5,68	1	0	probably_damaging	0,98	deleterious	0	neutral	2,26	deleterious	-5,35	deleterious	-2,65	high_impact	3,51	damaging	0,56	neutral	0,55	deleterious	4,26	23,9	0,15	0,65	NA	NA	disease	0,85	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,36	low_impact	-1,4	medium_impact	1,91	0,48	0,9	49,56	8,9	P	0,52	P	0,89	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4897	4897	A	G	MI.13660	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	428	143	Y	C	tAc/tGc	-0,66	0	0	benign	0,04	neutral	0,19	neutral	4,6	deleterious	-3,22	deleterious	-6,28	medium_impact	2,5	neutral	0,94	neutral	0,67	deleterious	3,38	22,9	0,05	0,35	disease	0,73	disease	0,75	disease	0,58	disease	0,59	2	neutral	0,8	deleterious	0,58	neutral	-3	neutral	0,27	medium_impact	0,47	medium_impact	-0,14	medium_impact	0,96	0,18	0,8	1,73	6,88	N	0,41	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4897	4897	A	C	MI.13661	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	428	143	Y	S	tAc/tCc	-0,66	0	0	possibly_damaging	0,53	neutral	0,34	neutral	4,62	neutral	-2,03	deleterious	-6,6	low_impact	1,27	neutral	0,89	damaging	0,18	deleterious	3,61	23,2	0,06	0,35	disease	0,58	disease	0,68	disease	0,61	disease	0,59	2	neutral	0,65	neutral	0,41	neutral	-3	deleterious	0,64	medium_impact	-0,84	medium_impact	0,05	medium_impact	-0,08	0,41	0,8	1,73	6,88	N	0,37	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4897	4897	A	T	MI.13662	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	428	143	Y	F	tAc/tTc	-0,66	0	0	benign	0,02	neutral	0,44	neutral	4,64	neutral	0,84	deleterious	-2,78	low_impact	1,12	neutral	0,9	neutral	0,78	deleterious	2,18	17,35	0,24	0,45	neutral	0,45	neutral	0,3	neutral	0,41	neutral	0,45	1	neutral	0,54	deleterious	0,71	neutral	-6	neutral	0,19	medium_impact	0,75	medium_impact	0,15	medium_impact	-0,2	0,64	0,8	1,73	6,88	N	0,4	N	0,33	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4899	4899	C	G	MI.13663	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	430	144	Q	E	Caa/Gaa	-3,88	0	0	probably_damaging	0,99	neutral	0,27	neutral	4,66	neutral	0,21	deleterious	-2,77	medium_impact	2,5	neutral	0,86	damaging	0,11	deleterious	2,99	22,2	0,31	0,45	disease	0,72	disease	0,7	disease	0,76	disease	0,71	4	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,84	low_impact	-2,62	medium_impact	-0,03	medium_impact	0,96	0,34	0,8	0,86	6,95	N	0,29	N	0,9	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4899	4899	C	A	MI.13664	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	430	144	Q	K	Caa/Aaa	-3,88	0	0	probably_damaging	0,99	neutral	0,29	neutral	4,68	neutral	0,49	deleterious	-3,59	medium_impact	2,84	neutral	0,83	damaging	0,12	deleterious	4,01	23,6	0,2	0,45	neutral	0,34	disease	0,76	disease	0,76	disease	0,7	4	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-2,62	medium_impact	-0,01	medium_impact	1,25	0,26	0,8	0,86	6,95	N	0,31	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4900	4900	A	G	MI.13665	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	431	144	Q	R	cAa/cGa	0,03	0	0	probably_damaging	0,99	neutral	0,35	neutral	5,04	neutral	2,7	deleterious	-3,6	medium_impact	3,04	neutral	0,83	damaging	0,12	deleterious	3,45	23	0,23	0,45	disease	0,79	disease	0,76	disease	0,79	disease	0,71	4	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,85	low_impact	-2,62	medium_impact	0,06	medium_impact	1,42	0,13	0,8	0,86	6,95	N	0,34	N	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4900	4900	A	T	MI.13666	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	431	144	Q	L	cAa/cTa	0,03	0	0	probably_damaging	1	neutral	0,67	neutral	4,6	neutral	-1,17	deleterious	-5,99	low_impact	0,96	neutral	0,9	neutral	0,55	deleterious	3,7	23,3	0,09	0,4	disease	0,68	disease	0,54	neutral	0,43	neutral	0,27	5	deleterious	1	neutral	0,34	neutral	-2	deleterious	0,78	low_impact	-3,54	medium_impact	0,38	medium_impact	-0,34	0,11	0,8	0,86	6,95	N	0,29	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4900	4900	A	C	MI.13667	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	431	144	Q	P	cAa/cCa	0,03	0	0	probably_damaging	1	neutral	0,2	neutral	4,58	neutral	-1,94	deleterious	-5,42	medium_impact	2,84	neutral	0,71	damaging	0,11	deleterious	3,3	22,9	0,03	0,35	disease	0,92	disease	0,88	disease	0,8	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,91	low_impact	-3,54	medium_impact	-0,13	medium_impact	1,25	0,24	0,8	0,86	6,95	N	0,31	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4901	4901	A	T	MI.13668	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	432	144	Q	H	caA/caT	2,79	0,31	0	probably_damaging	1	neutral	0,54	neutral	4,61	neutral	-0,76	deleterious	-4,57	medium_impact	2,84	neutral	0,87	neutral	0,3	deleterious	3,48	23,1	0,22	0,45	disease	0,9	disease	0,67	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	0,25	medium_impact	1,25	0,44	0,8	0,86	6,95	N	0,32	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4901	4901	A	C	MI.13669	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	432	144	Q	H	caA/caC	2,79	0,31	0	probably_damaging	1	neutral	0,54	neutral	4,61	neutral	-0,76	deleterious	-4,57	medium_impact	2,84	neutral	0,87	neutral	0,3	deleterious	3,31	22,9	0,22	0,45	disease	0,9	disease	0,67	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	0,25	medium_impact	1,25	0,44	0,8	0,86	6,95	N	0,32	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9167	9167	T	G	MI.1367	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	641	214	F	C	tTc/tGc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,16	deleterious	-10,17	deleterious	-7,05	high_impact	4,55	damaging	0,56	neutral	0,55	deleterious	4,16	23,8	0,14	0,65	NA	NA	disease	0,88	disease	0,69	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,6	low_impact	-1,4	high_impact	2,8	0,2	0,9	49,56	8,9	N	0,43	N	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4902	4902	A	C	MI.13670	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	433	145	I	L	Atc/Ctc	2,1	0,31	0	benign	0,09	neutral	1	neutral	4,89	neutral	1,51	neutral	-1,5	low_impact	1,04	neutral	0,84	neutral	0,92	deleterious	0,44	6,96	0,31	0,45	neutral	0,5	neutral	0,46	neutral	0,28	neutral	0,19	6	neutral	0,09	deleterious	0,96	neutral	-6	neutral	0,26	medium_impact	0,12	high_impact	1,87	medium_impact	-0,27	0,71	0,85	3,17	7,79	N	0,29	N	0,61	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4902	4902	A	T	MI.13671	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	433	145	I	F	Atc/Ttc	2,1	0,31	0	possibly_damaging	0,69	neutral	0,79	neutral	4,66	neutral	0,13	deleterious	-3,49	low_impact	1,62	neutral	0,92	neutral	0,74	deleterious	1,84	15,23	0,19	0,45	neutral	0,4	disease	0,68	disease	0,64	disease	0,68	4	neutral	0,62	deleterious	0,55	neutral	-3	deleterious	0,65	low_impact	-1,12	medium_impact	0,53	medium_impact	0,22	0,7	0,85	3,17	7,79	N	0,36	N	0,33	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4902	4902	A	G	MI.13672	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	433	145	I	V	Atc/Gtc	2,1	0,31	0	benign	0,02	neutral	0,5	neutral	4,71	neutral	0,56	neutral	-0,73	low_impact	1,75	neutral	0,93	neutral	0,71	neutral	0,94	10,29	0,43	0,55	disease	0,58	neutral	0,25	neutral	0,32	disease	0,55	1	neutral	0,47	deleterious	0,74	neutral	-6	neutral	0,16	medium_impact	0,75	medium_impact	0,21	medium_impact	0,33	0,52	0,8	3,17	7,79	N	0,32	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4903	4903	T	C	MI.13673	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	434	145	I	T	aTc/aCc	0,49	0,06	0	possibly_damaging	0,58	neutral	0,49	neutral	4,56	neutral	-1,15	deleterious	-3,9	neutral_impact	0,64	neutral	0,82	neutral	0,95	deleterious	0,49	7,39	0,08	0,35	neutral	0,35	neutral	0,11	neutral	0,33	neutral	0,32	4	neutral	0,57	neutral	0,46	neutral	-3	deleterious	0,55	medium_impact	-0,93	medium_impact	0,2	medium_impact	-0,61	0,28	0,8	3,17	7,79	N	0,43	N	0,56	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4903	4903	T	G	MI.13674	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	434	145	I	S	aTc/aGc	0,49	0,06	0	possibly_damaging	0,73	neutral	0,78	neutral	4,55	neutral	-1,42	deleterious	-5,05	low_impact	1,32	neutral	0,86	neutral	0,56	deleterious	2,58	19,97	0,03	0,35	disease	0,66	disease	0,71	disease	0,63	disease	0,59	2	neutral	0,67	deleterious	0,53	neutral	-3	deleterious	0,74	low_impact	-1,19	medium_impact	0,51	medium_impact	-0,03	0,14	0,8	3,17	7,79	N	0,21	N	0,51	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4903	4903	T	A	MI.13675	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	434	145	I	N	aTc/aAc	0,49	0,06	0	possibly_damaging	0,89	neutral	0,26	neutral	4,51	deleterious	-3,14	deleterious	-6,03	low_impact	1,59	neutral	0,9	neutral	0,63	deleterious	4,29	24	0,06	0,35	disease	0,86	disease	0,71	disease	0,64	disease	0,67	3	neutral	0,92	neutral	0,19	neutral	-3	deleterious	0,78	low_impact	-1,63	medium_impact	-0,04	medium_impact	0,19	0,13	0,8	3,17	7,79	N	0,45	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4904	4904	C	G	MI.13676	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	435	145	I	M	atC/atG	0,95	0,04	0	benign	0,11	neutral	0,35	neutral	4,64	neutral	-0,06	neutral	-2,19	low_impact	1,41	neutral	0,94	neutral	0,94	deleterious	0,3	5,68	0,28	0,45	disease	0,75	neutral	0,35	neutral	0,29	disease	0,64	3	neutral	0,6	deleterious	0,62	neutral	-6	neutral	0,31	medium_impact	0,03	medium_impact	0,06	medium_impact	0,04	0,63	0,8	3,17	7,79	N	0,42	N	0	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4904	4904	C	A	MI.13677	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	435	145	I	M	atC/atA	0,95	0,04	0	benign	0,11	neutral	0,35	neutral	4,64	neutral	-0,06	neutral	-2,19	low_impact	1,41	neutral	0,94	neutral	0,94	deleterious	0,7	8,84	0,28	0,45	disease	0,75	neutral	0,35	neutral	0,29	disease	0,64	3	neutral	0,6	deleterious	0,62	neutral	-6	neutral	0,31	medium_impact	0,03	medium_impact	0,06	medium_impact	0,04	0,63	0,8	3,17	7,79	N	0,43	N	0	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4905	4905	T	C	MI.13678	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	436	146	S	P	Tct/Cct	-8,49	0	0	possibly_damaging	0,64	neutral	0,21	neutral	4,49	deleterious	-3,42	deleterious	-2,77	low_impact	1,35	neutral	0,75	neutral	0,35	deleterious	2,59	20,1	0,07	0,35	neutral	0,42	disease	0,85	disease	0,64	disease	0,71	4	neutral	0,81	neutral	0,29	neutral	-3	deleterious	0,67	low_impact	-1,03	medium_impact	-0,11	medium_impact	-0,01	0,31	0,8	6,34	7,89	N	0,31	N	0,78	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4905	4905	T	G	MI.13679	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	436	146	S	A	Tct/Gct	-8,49	0	0	benign	0,12	neutral	0,52	neutral	4,55	neutral	-1,23	neutral	-0,64	low_impact	1,32	neutral	0,88	neutral	0,98	deleterious	0,13	3,93	0,29	0,45	neutral	0,42	neutral	0,23	neutral	0,28	neutral	0,43	1	neutral	0,39	deleterious	0,7	neutral	-6	neutral	0,26	medium_impact	-0,01	medium_impact	0,23	medium_impact	-0,03	0,42	0,8	6,34	7,89	N	0,4	N	0,31	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9168	9168	C	A	MI.1368	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	642	214	F	L	ttC/ttA	7,53	1	0	probably_damaging	0,98	deleterious	0,03	neutral	2,24	deleterious	-6,92	deleterious	-5,2	high_impact	3,58	damaging	0,54	neutral	0,64	deleterious	4,69	24,6	0,19	0,65	NA	NA	disease	0,87	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,85	low_impact	-2,36	medium_impact	-0,56	medium_impact	1,97	0,48	0,9	49,56	8,9	P	0,5	N	0,89	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4905	4905	T	A	MI.13680	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	436	146	S	T	Tct/Act	-8,49	0	0	benign	0,3	neutral	0,4	neutral	4,6	neutral	-0,43	neutral	-0,88	low_impact	1,17	neutral	0,88	neutral	0,92	deleterious	0,56	7,85	0,3	0,45	disease	0,6	neutral	0,45	neutral	0,29	disease	0,6	2	neutral	0,52	deleterious	0,55	neutral	-6	deleterious	0,44	medium_impact	-0,46	medium_impact	0,11	medium_impact	-0,16	0,52	0,8	6,34	7,89	N	0,39	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4906	4906	C	T	MI.13681	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	437	146	S	F	tCt/tTt	-3,88	0	0	benign	0	neutral	0,7	neutral	4,59	neutral	-0,61	neutral	-1,88	low_impact	1,21	neutral	0,94	neutral	0,92	deleterious	0,52	7,58	0,09	0,35	disease	0,55	disease	0,79	neutral	0,41	disease	0,54	1	neutral	0,29	deleterious	0,85	neutral	-6	neutral	0,2	medium_impact	1,95	medium_impact	0,41	medium_impact	-0,13	0,13	0,8	6,34	7,89	N	0,22	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4906	4906	C	G	MI.13682	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	437	146	S	C	tCt/tGt	-3,88	0	0	possibly_damaging	0,85	neutral	0,18	neutral	4,51	neutral	-2,32	neutral	-2,36	medium_impact	2,06	neutral	0,79	neutral	0,38	deleterious	2,36	18,53	0,09	0,35	disease	0,83	disease	0,72	neutral	0,39	disease	0,56	1	neutral	0,92	neutral	0,17	NA	0	deleterious	0,72	low_impact	-1,49	medium_impact	-0,16	medium_impact	0,59	0,24	0,8	6,34	7,89	N	0,3	N	0,56	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4906	4906	C	A	MI.13683	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	437	146	S	Y	tCt/tAt	-3,88	0	0	benign	0	neutral	1	neutral	4,56	neutral	-1,1	neutral	-1,3	low_impact	0,91	neutral	0,91	neutral	0,97	neutral	-0,23	0,97	0,07	0,35	disease	0,57	disease	0,71	neutral	0,38	disease	0,53	1	neutral	0	deleterious	1	neutral	-6	neutral	0,2	medium_impact	1,95	high_impact	1,87	medium_impact	-0,38	0,22	0,8	6,34	7,89	N	0,25	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4908	4908	C	T	MI.13684	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	439	147	P	S	Ccc/Tcc	-4,81	0	0	benign	0	neutral	0,49	neutral	4,61	neutral	-2,7	deleterious	-4,2	neutral_impact	0,6	neutral	0,92	neutral	0,99	deleterious	0,67	8,61	0,23	0,45	neutral	0,46	neutral	0,45	neutral	0,29	neutral	0,46	1	neutral	0,5	deleterious	0,75	neutral	-6	neutral	0,17	medium_impact	1,95	medium_impact	0,2	medium_impact	-0,64	0,04	0,8	2,88	9,03	N	0,42	N	0,02	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4908	4908	C	G	MI.13685	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	439	147	P	A	Ccc/Gcc	-4,81	0	0	benign	0,05	neutral	0,57	neutral	4,6	neutral	-2,66	deleterious	-4,9	low_impact	1,75	neutral	0,9	neutral	0,71	neutral	1,12	11,32	0,24	0,45	neutral	0,44	neutral	0,34	neutral	0,46	neutral	0,47	1	neutral	0,37	deleterious	0,76	neutral	-6	neutral	0,21	medium_impact	0,37	medium_impact	0,28	medium_impact	0,33	0,36	0,8	2,88	9,03	N	0,35	N	0,52	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4908	4908	C	A	MI.13686	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	439	147	P	T	Ccc/Acc	-4,81	0	0	benign	0,01	neutral	0,44	neutral	4,58	deleterious	-3,09	deleterious	-4,49	low_impact	1,52	neutral	0,94	neutral	0,85	deleterious	0,75	9,12	0,23	0,45	disease	0,53	neutral	0,44	neutral	0,32	neutral	0,36	3	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,18	medium_impact	1,03	medium_impact	0,15	medium_impact	0,14	0,36	0,8	2,88	9,03	N	0,38	N	0,59	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4909	4909	C	G	MI.13687	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	440	147	P	R	cCc/cGc	-5,27	0	0	possibly_damaging	0,44	neutral	0,39	neutral	4,57	deleterious	-3,53	deleterious	-5,42	medium_impact	3	neutral	0,87	neutral	0,35	deleterious	1,87	15,38	0,11	0,4	disease	0,76	disease	0,73	disease	0,59	disease	0,68	4	neutral	0,56	deleterious	0,48	NA	0	deleterious	0,57	medium_impact	-0,7	medium_impact	0,1	medium_impact	1,38	0,27	0,8	2,88	9,03	N	0,33	N	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4909	4909	C	A	MI.13688	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	440	147	P	H	cCc/cAc	-5,27	0	0	possibly_damaging	0,69	neutral	0,55	neutral	4,54	deleterious	-4,26	deleterious	-5,07	low_impact	0,96	neutral	0,84	neutral	0,95	deleterious	2,59	20,1	0,13	0,4	disease	0,81	neutral	0,4	neutral	0,4	disease	0,65	3	neutral	0,65	neutral	0,43	neutral	-3	deleterious	0,67	low_impact	-1,12	medium_impact	0,26	medium_impact	-0,34	0,18	0,8	2,88	9,03	N	0,32	N	0,76	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4909	4909	C	T	MI.13689	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	440	147	P	L	cCc/cTc	-5,27	0	0	benign	0,2	neutral	0,69	neutral	4,66	deleterious	-3,66	deleterious	-6,68	low_impact	1,31	neutral	0,9	neutral	0,58	deleterious	2,52	19,59	0,15	0,4	disease	0,71	disease	0,67	disease	0,55	disease	0,64	3	neutral	0,2	deleterious	0,75	neutral	-6	neutral	0,36	medium_impact	-0,25	medium_impact	0,4	medium_impact	-0,04	0,57	0,8	2,88	9,03	N	0,26	N	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9168	9168	C	G	MI.1369	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	642	214	F	L	ttC/ttG	7,53	1	0	probably_damaging	0,98	deleterious	0,03	neutral	2,24	deleterious	-6,92	deleterious	-5,2	high_impact	3,58	damaging	0,54	neutral	0,64	deleterious	4,4	24,1	0,19	0,65	NA	NA	disease	0,87	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,85	low_impact	-2,36	medium_impact	-0,56	medium_impact	1,97	0,48	0,9	49,56	8,9	N	0,49	N	0,89	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4911	4911	T	A	MI.13690	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	442	148	S	T	Tca/Aca	-2,73	0	0	benign	0,04	neutral	0,44	neutral	4,64	neutral	-0,18	neutral	-2,13	low_impact	1,5	neutral	0,91	neutral	0,96	deleterious	0,41	6,68	0,42	0,55	neutral	0,44	neutral	0,32	neutral	0,5	neutral	0,45	1	neutral	0,52	deleterious	0,7	neutral	-6	neutral	0,16	medium_impact	0,47	medium_impact	0,15	medium_impact	0,12	0,43	0,8	1,73	7,99	N	0,37	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4911	4911	T	C	MI.13691	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	442	148	S	P	Tca/Cca	-2,73	0	0	benign	0,03	neutral	0,22	neutral	4,63	neutral	-0,28	deleterious	-4,07	low_impact	1,88	neutral	0,95	neutral	0,61	deleterious	2,2	17,5	0,12	0,4	disease	0,91	disease	0,85	disease	0,76	disease	0,7	4	neutral	0,77	deleterious	0,6	neutral	-6	neutral	0,32	medium_impact	0,59	medium_impact	-0,1	medium_impact	0,44	0,12	0,8	1,73	7,99	N	0,39	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4911	4911	T	G	MI.13692	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	442	148	S	A	Tca/Gca	-2,73	0	0	benign	0,26	neutral	0,56	neutral	4,65	neutral	0,17	neutral	-2,24	medium_impact	2,04	neutral	0,92	neutral	0,85	deleterious	0,68	8,68	0,42	0,55	disease	0,7	neutral	0,37	disease	0,65	disease	0,67	3	neutral	0,33	deleterious	0,65	neutral	-3	neutral	0,42	medium_impact	-0,38	medium_impact	0,27	medium_impact	0,57	0,15	0,8	1,73	7,99	N	0,32	N	0,3	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4912	4912	C	G	MI.13693	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	443	148	S	W	tCa/tGa	-0,66	0	0	probably_damaging	0,92	neutral	0,19	neutral	4,59	neutral	-2,82	deleterious	-5,46	medium_impact	3,05	neutral	0,87	neutral	0,47	deleterious	4,11	23,7	0,09	0,4	disease	0,94	disease	0,85	disease	0,76	disease	0,72	4	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-1,77	medium_impact	-0,14	medium_impact	1,42	0,14	0,8	1,73	7,99	N	0,39	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4912	4912	C	T	MI.13694	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	443	148	S	L	tCa/tTa	-0,66	0	0	benign	0,1	neutral	0,69	neutral	5	neutral	2,84	deleterious	-4,4	low_impact	1,4	neutral	0,87	neutral	0,95	neutral	1,29	12,21	0,21	0,45	neutral	0,43	disease	0,75	disease	0,64	neutral	0,42	2	neutral	0,2	deleterious	0,8	neutral	-6	neutral	0,29	medium_impact	0,08	medium_impact	0,4	medium_impact	0,03	0,36	0,8	1,73	7,99	N	0,29	N	0,48	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4914	4914	C	G	MI.13695	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	445	149	L	V	Cta/Gta	-8,03	0	0	benign	0	neutral	0,65	neutral	4,53	neutral	-1,47	neutral	0,21	low_impact	1,51	neutral	0,88	neutral	0,85	deleterious	0,21	4,73	0,39	0,5	disease	0,62	neutral	0,34	neutral	0,45	disease	0,6	2	neutral	0,35	deleterious	0,83	neutral	-6	neutral	0,19	medium_impact	1,95	medium_impact	0,36	medium_impact	0,13	0,31	0,8	3,46	7,65	N	0,33	N	0,1	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4914	4914	C	A	MI.13696	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	445	149	L	M	Cta/Ata	-8,03	0	0	benign	0,01	neutral	0,38	neutral	4,52	neutral	-2,85	neutral	-0,3	neutral_impact	0,79	neutral	0,87	neutral	0,88	deleterious	0,4	6,61	0,3	0,45	disease	0,78	neutral	0,26	neutral	0,4	disease	0,58	2	neutral	0,61	deleterious	0,69	neutral	-6	neutral	0,2	medium_impact	1,03	medium_impact	0,09	medium_impact	-0,48	0,55	0,8	3,46	7,65	N	0,42	N	0,48	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4915	4915	T	C	MI.13697	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	446	149	L	P	cTa/cCa	-1,58	0	0	benign	0,24	neutral	0,23	neutral	4,46	deleterious	-5,02	deleterious	-4,71	medium_impact	2,39	neutral	0,76	neutral	0,36	deleterious	1,95	15,91	0,05	0,35	disease	0,86	disease	0,78	disease	0,78	disease	0,83	7	neutral	0,72	deleterious	0,5	neutral	-3	neutral	0,35	medium_impact	-0,34	medium_impact	-0,08	medium_impact	0,87	0,16	0,8	3,46	7,65	N	0,33	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4915	4915	T	G	MI.13698	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	446	149	L	R	cTa/cGa	-1,58	0	0	benign	0,19	neutral	0,33	neutral	4,45	deleterious	-3,85	deleterious	-4,43	medium_impact	3,08	neutral	0,79	neutral	0,4	deleterious	2,16	17,24	0,06	0,35	disease	0,77	disease	0,77	disease	0,78	disease	0,78	6	neutral	0,61	deleterious	0,57	neutral	-3	neutral	0,31	medium_impact	-0,22	medium_impact	0,04	medium_impact	1,45	0,11	0,8	3,46	7,65	N	0,36	N	0,86	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4915	4915	T	A	MI.13699	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	446	149	L	Q	cTa/cAa	-1,58	0	0	benign	0,24	neutral	0,3	neutral	4,45	deleterious	-3,84	deleterious	-4,24	medium_impact	2,39	neutral	0,82	neutral	0,48	deleterious	2,18	17,38	0,11	0,4	disease	0,67	disease	0,66	disease	0,66	disease	0,68	4	neutral	0,64	deleterious	0,53	neutral	-3	neutral	0,26	medium_impact	-0,34	medium_impact	0	medium_impact	0,87	0,13	0,8	3,46	7,65	N	0,31	N	0,83	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8591	8591	T	C	MI.137	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	65	22	L	P	cTg/cCg	-5,89	0	0	benign	0	neutral	0,06	neutral	4,11	deleterious	-4,23	deleterious	-3,66	low_impact	1,92	neutral	0,94	neutral	0,9	deleterious	0,56	7,86	0,16	0,65	disease	0,76	disease	0,73	disease	0,57	disease	0,59	2	neutral	0,94	deleterious	0,53	neutral	-6	neutral	0,3	high_impact	2,09	medium_impact	-0,38	medium_impact	0,55	0,6	0,9	25,22	20,33	N	0,37	N	0,13	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9169	9169	A	G	MI.1370	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	643	215	T	A	Aca/Gca	-3,34	0	0	probably_damaging	0,99	neutral	0,39	neutral	4,33	neutral	-0,94	deleterious	-2,7	neutral_impact	0,45	neutral	0,88	neutral	0,5	deleterious	2,47	19,26	0,32	0,65	NA	NA	neutral	0,44	neutral	0,3	neutral	0,2	6	deleterious	0,99	neutral	0,2	neutral	-2	deleterious	0,75	low_impact	-2,65	medium_impact	0,18	medium_impact	-0,71	0,48	0,9	46,9	8,38	N	0,3	N	0,63	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4917	4917	A	T	MI.13700	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	448	150	N	Y	Aac/Tac	-8,95	0	0,1	probably_damaging	0,97	neutral	1	neutral	4,54	neutral	-2,62	deleterious	-7,36	medium_impact	2,38	neutral	0,87	neutral	0,44	deleterious	3,59	23,2	0,15	0,4	disease	0,84	disease	0,85	disease	0,7	disease	0,66	3	neutral	0,97	deleterious	0,52	deleterious	1	deleterious	0,82	low_impact	-2,18	high_impact	1,87	medium_impact	0,86	0,17	0,8	NA	NA	N	0,24	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4917	4917	A	G	MI.13701	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	448	150	N	D	Aac/Gac	-8,95	0	0,1	benign	0,06	neutral	0,22	neutral	4,6	neutral	-0,42	deleterious	-3,86	low_impact	1,4	damaging	0,4	neutral	0,78	deleterious	0,7	8,8	0,4	0,5	disease	0,66	disease	0,67	neutral	0,49	neutral	0,21	6	neutral	0,76	deleterious	0,58	neutral	-6	neutral	0,27	medium_impact	0,3	medium_impact	-0,1	medium_impact	0,03	0,32	0,8	NA	NA	P	0,71	P	0,35	polymorphism	1	0,06	rs28357980	Uncertain significance	Leber's_optic_atrophy	RCV000010364.1	MedGen:OMIM:SNOMED_CT	.	.	.	.	A4917G	LHON/Insulin Resistance/AMD/NRTI-PN	+	-	Reported,haplogroup T marker	27
chrM	4917	4917	A	C	MI.13702	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	448	150	N	H	Aac/Cac	-8,95	0	0,1	probably_damaging	0,97	neutral	0,54	neutral	4,58	neutral	-1,28	deleterious	-4,55	low_impact	1,69	neutral	0,85	neutral	0,52	deleterious	2,94	22	0,32	0,5	disease	0,65	disease	0,78	disease	0,52	neutral	0,22	6	neutral	0,96	neutral	0,29	neutral	-2	deleterious	0,78	low_impact	-2,18	medium_impact	0,25	medium_impact	0,28	0,13	0,8	NA	NA	N	0,2	N	0,81	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4918	4918	A	T	MI.13703	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	449	150	N	I	aAc/aTc	2,1	0,41	0	probably_damaging	0,93	neutral	0,41	neutral	4,58	neutral	-2,68	deleterious	-8,23	medium_impact	2,56	neutral	0,84	neutral	0,54	deleterious	3,68	23,3	0,17	0,45	disease	0,64	disease	0,9	disease	0,65	disease	0,69	4	neutral	0,93	neutral	0,24	deleterious	1	deleterious	0,78	low_impact	-1,83	medium_impact	0,12	medium_impact	1,01	0,13	0,8	NA	NA	N	0,34	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4918	4918	A	G	MI.13704	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	449	150	N	S	aAc/aGc	2,1	0,41	0	possibly_damaging	0,56	neutral	0,43	neutral	4,7	neutral	0,16	deleterious	-4,35	low_impact	1,54	neutral	0,93	neutral	0,65	neutral	1,21	11,78	0,47	0,55	disease	0,52	disease	0,64	neutral	0,45	neutral	0,18	6	neutral	0,59	neutral	0,44	neutral	-3	deleterious	0,64	medium_impact	-0,89	medium_impact	0,14	medium_impact	0,15	0,21	0,8	NA	NA	N	0,38	N	0,79	polymorphism	1	0,06	rs879058895	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4918	4918	A	C	MI.13705	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	449	150	N	T	aAc/aCc	2,1	0,41	0	possibly_damaging	0,81	neutral	0,4	neutral	4,59	neutral	-0,77	deleterious	-5,38	medium_impact	2,12	neutral	0,83	neutral	0,57	deleterious	2,92	22	0,31	0,45	disease	0,52	disease	0,74	disease	0,65	neutral	0,42	2	neutral	0,81	neutral	0,3	NA	0	deleterious	0,71	low_impact	-1,37	medium_impact	0,11	medium_impact	0,64	0,21	0,8	NA	NA	N	0,32	N	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4919	4919	C	G	MI.13706	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	450	150	N	K	aaC/aaG	3,48	0,5	0	possibly_damaging	0,76	neutral	0,3	neutral	4,64	neutral	-0,83	deleterious	-5,4	low_impact	1,8	neutral	0,84	neutral	0,39	deleterious	2,34	18,44	0,31	0,45	disease	0,51	disease	0,83	disease	0,68	disease	0,68	4	neutral	0,81	neutral	0,27	neutral	-3	deleterious	0,74	low_impact	-1,26	medium_impact	0	medium_impact	0,37	0,29	0,8	NA	NA	N	0,36	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4919	4919	C	A	MI.13707	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	450	150	N	K	aaC/aaA	3,48	0,5	0	possibly_damaging	0,76	neutral	0,3	neutral	4,64	neutral	-0,83	deleterious	-5,4	low_impact	1,8	neutral	0,84	neutral	0,39	deleterious	2,85	21,6	0,31	0,45	disease	0,51	disease	0,83	disease	0,68	disease	0,68	4	neutral	0,81	neutral	0,27	neutral	-3	deleterious	0,74	low_impact	-1,26	medium_impact	0	medium_impact	0,37	0,29	0,8	NA	NA	N	0,36	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4920	4920	G	T	MI.13708	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	451	151	V	L	Gta/Tta	-0,89	0	0	benign	0	neutral	0,83	neutral	4,72	neutral	1,23	neutral	0,11	neutral_impact	-1,43	neutral	0,91	neutral	0,94	neutral	-0,63	0,11	0,36	0,5	neutral	0,45	neutral	0,27	neutral	0,3	neutral	0,44	1	neutral	0,16	deleterious	0,92	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,59	low_impact	-2,35	0,49	0,8	22,19	10,8	N	0,32	N	0,2	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4920	4920	G	A	MI.13709	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	451	151	V	M	Gta/Ata	-0,89	0	0	benign	0,02	neutral	0,27	neutral	4,63	neutral	-0,34	neutral	-0,01	neutral_impact	-1,05	neutral	0,93	neutral	0,93	deleterious	0,22	4,91	0,29	0,45	disease	0,77	neutral	0,22	neutral	0,21	disease	0,53	1	neutral	0,72	deleterious	0,63	neutral	-6	neutral	0,21	medium_impact	0,75	medium_impact	-0,03	low_impact	-2,03	0,52	0,8	22,19	10,8	N	0,44	N	0,17	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9169	9169	A	T	MI.1371	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	643	215	T	S	Aca/Tca	-3,34	0	0	probably_damaging	0,99	neutral	0,94	neutral	4,37	neutral	-2,36	deleterious	-2,78	low_impact	0,8	neutral	0,83	damaging	0,11	deleterious	3,37	22,9	0,25	0,65	NA	NA	neutral	0,48	neutral	0,28	neutral	0,31	4	deleterious	0,99	deleterious	0,48	neutral	-2	deleterious	0,77	low_impact	-2,65	medium_impact	0,97	medium_impact	-0,41	0,56	0,9	46,9	8,38	N	0,16	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4920	4920	G	C	MI.13710	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	451	151	V	L	Gta/Cta	-0,89	0	0	benign	0	neutral	0,83	neutral	4,72	neutral	1,23	neutral	0,11	neutral_impact	-1,43	neutral	0,91	neutral	0,94	neutral	-0,75	0,06	0,36	0,5	neutral	0,45	neutral	0,27	neutral	0,3	neutral	0,44	1	neutral	0,16	deleterious	0,92	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,59	low_impact	-2,35	0,49	0,8	22,19	10,8	N	0,32	N	0,2	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4921	4921	T	C	MI.13711	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	452	151	V	A	gTa/gCa	-5,04	0	0	benign	0,09	neutral	0,53	neutral	4,68	neutral	0,62	neutral	-0,38	neutral_impact	-0,18	neutral	0,89	neutral	0,8	neutral	-0,24	0,89	0,23	0,45	disease	0,59	neutral	0,2	neutral	0,37	neutral	0,48	0	neutral	0,39	deleterious	0,72	neutral	-6	neutral	0,24	medium_impact	0,12	medium_impact	0,24	low_impact	-1,3	0,15	0,8	22,19	10,8	N	0,33	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4921	4921	T	A	MI.13712	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	452	151	V	E	gTa/gAa	-5,04	0	0	benign	0,27	neutral	0,27	neutral	4,66	neutral	0,34	neutral	-1,17	neutral_impact	-0,06	neutral	0,88	neutral	0,58	neutral	1,35	12,52	0,05	0,35	disease	0,91	disease	0,69	disease	0,52	disease	0,63	3	neutral	0,67	deleterious	0,5	neutral	-6	deleterious	0,57	medium_impact	-0,4	medium_impact	-0,03	low_impact	-1,2	0,14	0,8	22,19	10,8	N	0,32	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4921	4921	T	G	MI.13713	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	452	151	V	G	gTa/gGa	-5,04	0	0	benign	0,21	neutral	0,35	neutral	4,61	neutral	-0,96	neutral	-2,16	neutral_impact	-0,22	neutral	0,86	neutral	0,49	deleterious	0,39	6,52	0,09	0,35	disease	0,71	neutral	0,4	neutral	0,4	disease	0,65	3	neutral	0,58	deleterious	0,57	neutral	-6	deleterious	0,44	medium_impact	-0,27	medium_impact	0,06	low_impact	-1,33	0,23	0,8	22,19	10,8	N	0,3	N	0,44	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4923	4923	A	G	MI.13714	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	454	152	S	G	Agc/Ggc	-7,34	0	0	benign	0,14	neutral	0,38	neutral	4,55	neutral	-2	neutral	-1,52	neutral_impact	0,74	neutral	0,94	neutral	0,62	neutral	1,6	13,83	0,26	0,45	neutral	0,5	neutral	0,19	neutral	0,47	neutral	0,25	5	neutral	0,55	deleterious	0,62	neutral	-6	neutral	0,24	medium_impact	-0,08	medium_impact	0,09	medium_impact	-0,52	0,49	0,8	10,66	8,21	N	0,37	N	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4923	4923	A	T	MI.13715	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	454	152	S	C	Agc/Tgc	-7,34	0	0	benign	0,02	neutral	0,18	neutral	4,53	deleterious	-3,55	deleterious	-3,25	low_impact	1,29	neutral	0,88	neutral	0,74	deleterious	3,24	22,8	0,13	0,4	disease	0,96	neutral	0,4	neutral	0,48	disease	0,66	3	neutral	0,81	deleterious	0,58	neutral	-6	neutral	0,22	medium_impact	0,75	medium_impact	-0,16	medium_impact	-0,06	0,28	0,8	10,66	8,21	N	0,4	N	0,42	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4923	4923	A	C	MI.13716	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	454	152	S	R	Agc/Cgc	-7,34	0	0	benign	0,39	neutral	0,35	neutral	4,57	neutral	-1,31	neutral	-1,25	low_impact	1,84	neutral	0,87	neutral	0,51	deleterious	1,97	16	0,09	0,35	disease	0,81	disease	0,5	disease	0,57	disease	0,66	3	neutral	0,59	deleterious	0,48	neutral	-6	deleterious	0,52	medium_impact	-0,62	medium_impact	0,06	medium_impact	0,4	0,39	0,8	10,66	8,21	N	0,34	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4924	4924	G	T	MI.13717	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	455	152	S	I	aGc/aTc	-3,88	0	0,01	benign	0,39	neutral	0,5	neutral	4,63	neutral	-0,2	deleterious	-3,24	neutral_impact	0,28	neutral	0,88	neutral	0,66	deleterious	3,58	23,2	0,12	0,4	disease	0,88	neutral	0,43	neutral	0,48	disease	0,66	3	neutral	0,43	deleterious	0,56	neutral	-6	deleterious	0,52	medium_impact	-0,62	medium_impact	0,21	medium_impact	-0,91	0,29	0,8	10,66	8,21	N	0,32	N	0,33	polymorphism	1	0,05	rs386828956	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4924	4924	G	A	MI.13718	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	455	152	S	N	aGc/aAc	-3,88	0	0,01	benign	0	neutral	0,37	neutral	4,68	neutral	0,38	neutral	2,47	neutral_impact	-1,2	neutral	0,93	neutral	0,99	neutral	-1,04	0,01	0,45	0,55	disease	0,68	neutral	0,12	neutral	0,32	neutral	0,35	3	neutral	0,63	deleterious	0,69	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,08	low_impact	-2,15	0,32	0,8	10,66	8,21	N	0,34	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4924	4924	G	C	MI.13719	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	455	152	S	T	aGc/aCc	-3,88	0	0,01	benign	0,01	neutral	0,46	neutral	4,62	neutral	-0,35	neutral	-0,29	neutral_impact	-1,08	neutral	0,94	neutral	0,96	neutral	-0,17	1,28	0,31	0,45	disease	0,52	neutral	0,03	neutral	0,26	neutral	0,16	7	neutral	0,53	deleterious	0,73	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,17	low_impact	-2,05	0,42	0,8	10,66	8,21	N	0,44	N	0,03	polymorphism	1	0	rs386828956	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9169	9169	A	C	MI.1372	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	643	215	T	P	Aca/Cca	-3,34	0	0	probably_damaging	1	neutral	0,06	neutral	4,18	deleterious	-4,98	deleterious	-4,06	medium_impact	3	neutral	0,75	damaging	0,08	deleterious	3,61	23,2	0,11	0,65	NA	NA	disease	0,91	disease	0,67	disease	0,81	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,88	low_impact	-3,6	medium_impact	-0,38	medium_impact	1,47	0,52	0,9	46,9	8,38	N	0,25	N	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4926	4926	C	G	MI.13720	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	457	153	L	V	Ctt/Gtt	-9,87	0	0	benign	0	neutral	0,35	neutral	4,61	neutral	-0,87	neutral	-1,74	low_impact	1,77	neutral	0,92	neutral	0,79	deleterious	0,36	6,27	0,3	0,45	disease	0,76	neutral	0,3	neutral	0,45	disease	0,62	2	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,18	medium_impact	1,95	medium_impact	0,06	medium_impact	0,35	0,6	0,8	NA	NA	N	0,4	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4926	4926	C	A	MI.13721	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	457	153	L	I	Ctt/Att	-9,87	0	0	benign	0	neutral	0,66	neutral	4,68	neutral	-0,96	neutral	-0,98	neutral_impact	0,64	neutral	0,89	neutral	0,9	deleterious	0,16	4,21	0,25	0,45	disease	0,57	neutral	0,18	neutral	0,36	neutral	0,32	4	neutral	0,33	deleterious	0,83	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,37	medium_impact	-0,61	0,38	0,8	NA	NA	N	0,38	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4926	4926	C	T	MI.13722	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	457	153	L	F	Ctt/Ttt	-9,87	0	0	benign	0,18	neutral	0,41	neutral	4,6	neutral	-2,61	deleterious	-3,02	low_impact	1,34	neutral	0,91	neutral	0,62	deleterious	2,25	17,82	0,25	0,45	neutral	0,49	neutral	0,49	disease	0,59	disease	0,52	0	neutral	0,51	deleterious	0,62	neutral	-6	neutral	0,43	medium_impact	-0,19	medium_impact	0,12	medium_impact	-0,02	0,54	0,8	NA	NA	N	0,3	N	0,35	polymorphism	1	0,05	rs28429662	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4927	4927	T	A	MI.13723	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	458	153	L	H	cTt/cAt	-7,57	0	0	possibly_damaging	0,77	neutral	0,23	neutral	4,42	deleterious	-5,29	deleterious	-5,77	medium_impact	3,48	neutral	0,84	neutral	0,38	deleterious	3,93	23,5	0,04	0,35	disease	0,95	disease	0,69	disease	0,75	disease	0,73	5	neutral	0,85	neutral	0,23	NA	0	deleterious	0,77	low_impact	-1,28	medium_impact	-0,08	medium_impact	1,79	0,25	0,8	NA	NA	N	0,34	N	0,79	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4927	4927	T	G	MI.13724	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	458	153	L	R	cTt/cGt	-7,57	0	0	benign	0,33	neutral	0,14	neutral	4,43	deleterious	-4,89	deleterious	-5,01	medium_impact	3,48	neutral	0,81	neutral	0,36	deleterious	3,94	23,5	0,02	0,35	disease	0,94	disease	0,74	disease	0,79	disease	0,75	5	neutral	0,83	neutral	0,41	neutral	-3	deleterious	0,64	medium_impact	-0,52	medium_impact	-0,23	medium_impact	1,79	0,19	0,8	NA	NA	N	0,38	N	0,89	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4927	4927	T	C	MI.13725	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	458	153	L	P	cTt/cCt	-7,57	0	0	benign	0,29	neutral	0,08	neutral	4,45	deleterious	-4,4	deleterious	-5,72	medium_impact	2,58	neutral	0,88	neutral	0,49	deleterious	3,54	23,1	0,03	0,35	disease	0,95	disease	0,72	disease	0,78	disease	0,75	5	neutral	0,91	neutral	0,4	neutral	-3	deleterious	0,65	medium_impact	-0,44	medium_impact	-0,38	medium_impact	1,03	0,24	0,8	NA	NA	N	0,36	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4929	4929	C	G	MI.13726	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	460	154	L	V	Ctc/Gtc	-7,57	0	0	possibly_damaging	0,71	neutral	0,34	neutral	4,41	neutral	-1,75	neutral	-1,66	medium_impact	1,94	neutral	0,95	neutral	0,63	deleterious	3,33	22,9	0,22	0,45	disease	0,73	neutral	0,4	disease	0,59	disease	0,61	2	neutral	0,75	neutral	0,32	NA	0	deleterious	0,68	low_impact	-1,15	medium_impact	0,05	medium_impact	0,49	0,46	0,8	1,15	7,17	N	0,4	N	0,39	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4929	4929	C	A	MI.13727	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	460	154	L	I	Ctc/Atc	-7,57	0	0	possibly_damaging	0,45	neutral	0,8	neutral	4,53	neutral	-1,71	neutral	-0,91	neutral_impact	0,73	neutral	0,95	neutral	0,9	deleterious	2,61	20,3	0,24	0,45	disease	0,59	neutral	0,37	neutral	0,42	disease	0,56	1	neutral	0,34	deleterious	0,68	neutral	-3	deleterious	0,55	medium_impact	-0,72	medium_impact	0,54	medium_impact	-0,53	0,32	0,8	1,15	7,17	N	0,28	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4929	4929	C	T	MI.13728	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	460	154	L	F	Ctc/Ttc	-7,57	0	0	probably_damaging	0,98	neutral	0,32	neutral	4,36	deleterious	-3,01	deleterious	-3,16	low_impact	1,7	neutral	0,95	damaging	0,24	deleterious	3,94	23,5	0,18	0,45	disease	0,8	disease	0,53	disease	0,67	disease	0,66	3	deleterious	0,98	neutral	0,17	neutral	-2	deleterious	0,76	low_impact	-2,34	medium_impact	0,03	medium_impact	0,29	0,28	0,8	1,15	7,17	N	0,35	N	0,33	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4930	4930	T	A	MI.13729	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	461	154	L	H	cTc/cAc	-5,96	0	0	probably_damaging	0,99	neutral	0,14	neutral	4,24	deleterious	-5,54	deleterious	-5,91	high_impact	3,62	neutral	0,91	damaging	0,14	deleterious	4,01	23,6	0,04	0,35	disease	0,96	disease	0,7	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-2,62	medium_impact	-0,23	medium_impact	1,9	0,26	0,8	1,15	7,17	N	0,41	N	0,8	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9170	9170	C	T	MI.1373	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	644	215	T	M	aCa/aTa	2,67	0,98	0	probably_damaging	1	neutral	0,09	neutral	4,27	neutral	-2,61	deleterious	-3,15	low_impact	1,62	neutral	0,88	damaging	0,1	deleterious	4,16	23,8	0,16	0,65	NA	NA	disease	0,7	neutral	0,45	disease	0,51	0	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,8	low_impact	-3,6	medium_impact	-0,28	medium_impact	0,29	0,74	0,9	46,9	8,38	N	0,43	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4930	4930	T	G	MI.13730	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	461	154	L	R	cTc/cGc	-5,96	0	0	probably_damaging	0,99	neutral	0,07	neutral	4,25	deleterious	-5,31	deleterious	-5,16	high_impact	3,62	neutral	0,86	damaging	0,12	deleterious	4,07	23,7	0,02	0,35	disease	0,95	disease	0,76	disease	0,78	disease	0,77	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,86	low_impact	-2,62	medium_impact	-0,42	medium_impact	1,9	0,2	0,8	1,15	7,17	N	0,36	N	0,85	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4930	4930	T	C	MI.13731	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	461	154	L	P	cTc/cCc	-5,96	0	0	probably_damaging	0,99	neutral	0,05	neutral	4,24	deleterious	-5,69	deleterious	-5,87	medium_impact	2,93	neutral	0,93	damaging	0,15	deleterious	3,82	23,4	0,02	0,35	disease	0,93	disease	0,72	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,84	low_impact	-2,62	medium_impact	-0,5	medium_impact	1,32	0,41	0,8	1,15	7,17	N	0,45	N	0,91	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4932	4932	C	G	MI.13732	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	463	155	L	V	Ctc/Gtc	-9,41	0	0	possibly_damaging	0,79	neutral	0,52	neutral	4,55	neutral	-0,88	neutral	-1,87	low_impact	0,97	neutral	0,9	neutral	0,94	deleterious	2,26	17,88	0,2	0,45	disease	0,68	neutral	0,19	neutral	0,32	neutral	0,49	0	neutral	0,77	neutral	0,37	neutral	-3	deleterious	0,64	low_impact	-1,32	medium_impact	0,23	medium_impact	-0,33	0,37	0,8	3,75	9,12	N	0,39	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4932	4932	C	T	MI.13733	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	463	155	L	F	Ctc/Ttc	-9,41	0	0	probably_damaging	0,95	neutral	0,51	neutral	4,44	neutral	-2,23	deleterious	-3,08	low_impact	1,55	neutral	0,93	neutral	0,76	deleterious	2,88	21,8	0,2	0,45	disease	0,61	neutral	0,35	neutral	0,36	disease	0,6	2	neutral	0,95	neutral	0,28	neutral	-2	deleterious	0,69	low_impact	-1,97	medium_impact	0,22	medium_impact	0,16	0,42	0,8	3,75	9,12	N	0,33	N	0,55	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4932	4932	C	A	MI.13734	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	463	155	L	I	Ctc/Atc	-9,41	0	0	possibly_damaging	0,79	neutral	0,91	neutral	4,55	neutral	-0,78	neutral	-1,36	low_impact	0,92	neutral	0,88	neutral	0,96	deleterious	2,42	18,98	0,25	0,45	disease	0,54	neutral	0,12	neutral	0,22	neutral	0,29	4	neutral	0,77	deleterious	0,56	neutral	-3	deleterious	0,63	low_impact	-1,32	medium_impact	0,77	medium_impact	-0,37	0,37	0,8	3,75	9,12	N	0,31	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4933	4933	T	G	MI.13735	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	464	155	L	R	cTc/cGc	-10,1	0	0	probably_damaging	0,98	neutral	0,28	neutral	4,37	deleterious	-4,15	deleterious	-4,62	medium_impact	3,35	neutral	0,84	neutral	0,38	deleterious	4,15	23,8	0,02	0,35	disease	0,93	disease	0,67	disease	0,69	disease	0,72	4	neutral	0,98	neutral	0,15	deleterious	1	deleterious	0,84	low_impact	-2,34	medium_impact	-0,02	medium_impact	1,68	0,2	0,8	3,75	9,12	N	0,35	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4933	4933	T	C	MI.13736	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	464	155	L	P	cTc/cCc	-10,1	0	0	probably_damaging	0,99	neutral	0,17	neutral	4,37	deleterious	-4,74	deleterious	-5,47	medium_impact	2,54	neutral	0,93	neutral	0,57	deleterious	3,84	23,4	0,02	0,35	disease	0,92	disease	0,73	disease	0,7	disease	0,67	3	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-2,62	medium_impact	-0,17	medium_impact	0,99	0,25	0,8	3,75	9,12	N	0,47	N	0,94	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4933	4933	T	A	MI.13737	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	464	155	L	H	cTc/cAc	-10,1	0	0	probably_damaging	0,99	neutral	0,29	neutral	4,37	deleterious	-4,73	deleterious	-5,55	medium_impact	3,35	neutral	0,85	neutral	0,41	deleterious	4,09	23,7	0,05	0,35	disease	0,9	disease	0,52	disease	0,64	disease	0,69	4	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,78	low_impact	-2,62	medium_impact	-0,01	medium_impact	1,68	0,22	0,8	3,75	9,12	N	0,38	N	0,85	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4935	4935	A	T	MI.13738	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	466	156	T	S	Act/Tct	-6,19	0	0	benign	0,14	neutral	0,58	neutral	4,57	neutral	-1,16	neutral	-2,06	neutral_impact	0,68	neutral	0,74	neutral	0,96	deleterious	0,1	3,61	0,34	0,5	neutral	0,4	neutral	0,3	neutral	0,33	neutral	0,44	1	neutral	0,32	deleterious	0,72	neutral	-6	neutral	0,28	medium_impact	-0,08	medium_impact	0,29	medium_impact	-0,57	0,54	0,8	2,59	7,69	N	0,33	N	0,37	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4935	4935	A	C	MI.13739	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	466	156	T	P	Act/Cct	-6,19	0	0	possibly_damaging	0,46	neutral	0,21	neutral	4,53	deleterious	-3,1	deleterious	-3,43	low_impact	1,24	neutral	0,93	neutral	0,77	deleterious	2,03	16,4	0,05	0,35	disease	0,86	disease	0,74	disease	0,54	neutral	0,48	0	neutral	0,76	neutral	0,38	neutral	-3	deleterious	0,7	medium_impact	-0,73	medium_impact	-0,11	medium_impact	-0,1	0,41	0,8	2,59	7,69	N	0,41	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9170	9170	C	A	MI.1374	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	644	215	T	K	aCa/aAa	2,67	0,98	0	probably_damaging	1	neutral	0,05	neutral	4,2	deleterious	-4,07	deleterious	-4,04	medium_impact	3	neutral	0,85	damaging	0,08	deleterious	4,54	24,3	0,11	0,65	NA	NA	disease	0,85	disease	0,66	disease	0,79	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	-0,43	medium_impact	1,47	0,64	0,9	46,9	8,38	N	0,41	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4935	4935	A	G	MI.13740	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	466	156	T	A	Act/Gct	-6,19	0	0	benign	0	neutral	0,61	neutral	4,63	neutral	-0,15	neutral	-2,17	low_impact	1,04	neutral	0,97	neutral	0,96	deleterious	0,2	4,72	0,19	0,45	disease	0,52	neutral	0,25	neutral	0,35	neutral	0,34	3	neutral	0,38	deleterious	0,81	neutral	-6	neutral	0,13	medium_impact	1,95	medium_impact	0,32	medium_impact	-0,27	0,22	0,8	2,59	7,69	N	0,28	N	0,73	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4936	4936	C	T	MI.13741	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	467	156	T	I	aCt/aTt	-5,96	0	0	benign	0,01	neutral	0,5	neutral	4,84	neutral	1,44	neutral	-2,23	neutral_impact	0,61	neutral	0,95	neutral	0,96	deleterious	1,88	15,45	0,1	0,4	neutral	0,4	neutral	0,43	neutral	0,35	neutral	0,44	1	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	0,21	medium_impact	-0,63	0,5	0,8	2,59	7,69	N	0,35	N	0,45	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4936	4936	C	A	MI.13742	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	467	156	T	N	aCt/aAt	-5,96	0	0	possibly_damaging	0,55	neutral	0,34	neutral	4,53	neutral	-2,81	deleterious	-3,21	medium_impact	2,58	neutral	0,85	neutral	0,47	deleterious	2,2	17,51	0,19	0,45	disease	0,83	disease	0,51	neutral	0,48	neutral	0,48	0	neutral	0,66	neutral	0,4	NA	0	deleterious	0,66	medium_impact	-0,88	medium_impact	0,05	medium_impact	1,03	0,46	0,8	2,59	7,69	N	0,34	N	0,7	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4936	4936	C	G	MI.13743	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	467	156	T	S	aCt/aGt	-5,96	0	0	benign	0,14	neutral	0,58	neutral	4,57	neutral	-1,16	neutral	-2,06	neutral_impact	0,68	neutral	0,74	neutral	0,96	deleterious	0,31	5,77	0,34	0,5	neutral	0,4	neutral	0,3	neutral	0,33	neutral	0,44	1	neutral	0,32	deleterious	0,72	neutral	-6	neutral	0,28	medium_impact	-0,08	medium_impact	0,29	medium_impact	-0,57	0,54	0,8	2,59	7,69	N	0,32	N	0,37	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4938	4938	C	G	MI.13744	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	469	157	L	V	Ctc/Gtc	-12,63	0	0	benign	0,22	neutral	0,54	neutral	4,51	neutral	-1,64	neutral	-0,63	low_impact	1,5	neutral	0,93	neutral	0,67	deleterious	0,59	8,07	0,26	0,45	disease	0,55	neutral	0,47	disease	0,62	disease	0,63	3	neutral	0,35	deleterious	0,66	neutral	-6	deleterious	0,44	medium_impact	-0,29	medium_impact	0,25	medium_impact	0,12	0,57	0,8	5,48	8,98	N	0,28	N	0,39	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4938	4938	C	T	MI.13745	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	469	157	L	F	Ctc/Ttc	-12,63	0	0	benign	0,05	neutral	0,74	neutral	4,38	neutral	-2,39	neutral	-1,99	low_impact	1,7	neutral	0,94	neutral	0,84	deleterious	0,82	9,61	0,2	0,45	neutral	0,47	disease	0,59	neutral	0,46	neutral	0,17	7	neutral	0,18	deleterious	0,85	neutral	-6	neutral	0,2	medium_impact	0,37	medium_impact	0,46	medium_impact	0,29	0,48	0,8	5,48	8,98	N	0,22	N	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4938	4938	C	A	MI.13746	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	469	157	L	I	Ctc/Atc	-12,63	0	0	benign	0,04	neutral	0,43	neutral	4,59	neutral	-1,5	neutral	-0,46	low_impact	1,06	neutral	0,92	neutral	0,93	neutral	0,96	10,46	0,23	0,45	neutral	0,36	neutral	0,46	neutral	0,35	neutral	0,39	2	neutral	0,54	deleterious	0,7	neutral	-6	neutral	0,19	medium_impact	0,47	medium_impact	0,14	medium_impact	-0,25	0,44	0,8	5,48	8,98	N	0,39	N	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4939	4939	T	C	MI.13747	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	470	157	L	P	cTc/cCc	-2,5	0	0	probably_damaging	0,92	neutral	0,2	neutral	4,3	deleterious	-5,74	deleterious	-3,76	medium_impact	2,38	neutral	0,74	neutral	0,35	deleterious	3,8	23,4	0,02	0,35	disease	0,93	disease	0,86	disease	0,75	disease	0,65	3	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,85	low_impact	-1,77	medium_impact	-0,13	medium_impact	0,86	0,33	0,8	5,48	8,98	N	0,3	N	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4939	4939	T	G	MI.13748	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	470	157	L	R	cTc/cGc	-2,5	0	0	possibly_damaging	0,89	neutral	0,34	neutral	4,31	deleterious	-5,39	deleterious	-3,15	medium_impact	3,42	neutral	0,81	neutral	0,4	deleterious	4,07	23,7	0,02	0,35	disease	0,9	disease	0,85	disease	0,75	disease	0,64	3	neutral	0,9	neutral	0,23	NA	0	deleterious	0,83	low_impact	-1,63	medium_impact	0,05	medium_impact	1,73	0,2	0,8	5,48	8,98	N	0,36	N	0,96	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4939	4939	T	A	MI.13749	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	470	157	L	H	cTc/cAc	-2,5	0	0	probably_damaging	0,95	neutral	0,54	neutral	4,3	deleterious	-5,91	deleterious	-3,87	medium_impact	3,42	neutral	0,84	neutral	0,46	deleterious	4,03	23,6	0,04	0,35	disease	0,93	disease	0,73	disease	0,72	disease	0,7	4	neutral	0,94	neutral	0,3	deleterious	1	deleterious	0,8	low_impact	-1,97	medium_impact	0,25	medium_impact	1,73	0,3	0,8	5,48	8,98	N	0,27	N	0,85	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9172	9172	C	A	MI.1375	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	646	216	L	I	Ctt/Att	-14,68	0	0	probably_damaging	0,99	neutral	0,25	neutral	4,47	neutral	-0,6	neutral	-1,72	low_impact	1,1	neutral	0,85	damaging	0,16	deleterious	4,26	23,9	0,29	0,65	NA	NA	neutral	0,43	neutral	0,27	neutral	0,22	6	deleterious	0,99	neutral	0,13	neutral	-2	deleterious	0,78	low_impact	-2,65	medium_impact	0,02	medium_impact	-0,16	0,64	0,9	48,23	8,94	N	0,32	N	0,87	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4941	4941	T	G	MI.13750	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	472	158	S	A	Tca/Gca	-0,43	0	0	probably_damaging	1	neutral	0,52	neutral	4,65	neutral	1,29	neutral	0,12	neutral_impact	-0,84	neutral	0,93	neutral	0,97	neutral	0,9	10,08	0,27	0,45	neutral	0,5	neutral	0,1	neutral	0,3	neutral	0,17	7	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,68	low_impact	-3,54	medium_impact	0,23	low_impact	-1,85	0,45	0,8	0,29	7,41	N	0,47	N	0,1	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4941	4941	T	A	MI.13751	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	472	158	S	T	Tca/Aca	-0,43	0	0	probably_damaging	1	neutral	0,39	neutral	4,48	neutral	-1,94	neutral	-1,83	low_impact	1,82	neutral	0,91	neutral	0,36	deleterious	3,67	23,2	0,28	0,45	disease	0,67	neutral	0,4	disease	0,58	disease	0,66	3	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	0,1	medium_impact	0,39	0,62	0,8	0,29	7,41	N	0,42	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4941	4941	T	C	MI.13752	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	472	158	S	P	Tca/Cca	-0,43	0	0	probably_damaging	1	neutral	0,2	neutral	4,44	deleterious	-4,15	deleterious	-3,15	medium_impact	2,5	neutral	0,7	damaging	0,1	deleterious	3,93	23,5	0,04	0,35	disease	0,89	disease	0,9	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,88	low_impact	-3,54	medium_impact	-0,13	medium_impact	0,96	0,27	0,8	0,29	7,41	N	0,26	N	0,92	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4942	4942	C	G	MI.13753	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	473	158	S	W	tCa/tGa	0,72	0	0	probably_damaging	1	neutral	0,19	neutral	4,43	deleterious	-5,48	deleterious	-4,84	medium_impact	2,16	neutral	0,86	damaging	0,12	deleterious	4,3	24	0,05	0,35	disease	0,92	disease	0,88	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	-0,14	medium_impact	0,67	0,15	0,8	0,29	7,41	N	0,29	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4942	4942	C	T	MI.13754	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	473	158	S	L	tCa/tTa	0,72	0	0	probably_damaging	1	neutral	0,66	neutral	4,56	neutral	-1,92	deleterious	-3,81	low_impact	1,26	neutral	0,88	damaging	0,15	deleterious	4,6	24,4	0,06	0,35	neutral	0,41	disease	0,77	disease	0,56	disease	0,7	4	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	0,37	medium_impact	-0,08	0,37	0,8	0,29	7,41	N	0,25	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4944	4944	A	T	MI.13755	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	475	159	I	F	Atc/Ttc	-14,47	0	0	benign	0,39	neutral	0,71	neutral	4,47	neutral	-2,17	neutral	-2,34	medium_impact	1,97	neutral	0,93	neutral	0,95	deleterious	3,37	22,9	0,17	0,45	disease	0,59	disease	0,67	disease	0,55	disease	0,56	1	neutral	0,29	deleterious	0,66	neutral	-3	deleterious	0,48	medium_impact	-0,62	medium_impact	0,42	medium_impact	0,51	0,38	0,8	NA	NA	N	0,24	N	0,68	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4944	4944	A	G	MI.13756	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	475	159	I	V	Atc/Gtc	-14,47	0	0	benign	0,01	neutral	0,6	neutral	4,61	neutral	0,39	neutral	-0,44	low_impact	0,96	neutral	0,93	neutral	0,96	neutral	-0,2	1,1	0,44	0,55	disease	0,51	neutral	0,21	neutral	0,39	neutral	0,28	4	neutral	0,38	deleterious	0,8	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	0,31	medium_impact	-0,34	0,34	0,8	NA	NA	N	0,33	N	0,1	polymorphism	1	0,01	rs878971699	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4944	4944	A	C	MI.13757	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	475	159	I	L	Atc/Ctc	-14,47	0	0	benign	0,01	neutral	1	neutral	4,59	neutral	0,05	neutral	0,16	neutral_impact	-0,05	neutral	0,9	neutral	0,97	neutral	-0,53	0,18	0,26	0,45	neutral	0,36	neutral	0,22	neutral	0,25	neutral	0,41	2	neutral	0,01	deleterious	1	neutral	-6	neutral	0,1	medium_impact	1,03	high_impact	1,87	low_impact	-1,19	0,39	0,8	NA	NA	N	0,36	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4945	4945	T	A	MI.13758	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	476	159	I	N	aTc/aAc	-8,26	0	0	benign	0,39	neutral	0,37	neutral	4,4	deleterious	-4,57	deleterious	-4,58	medium_impact	2,74	neutral	0,89	neutral	0,49	deleterious	2,93	22	0,15	0,4	disease	0,89	disease	0,73	disease	0,62	disease	0,67	3	neutral	0,57	deleterious	0,49	neutral	-3	deleterious	0,62	medium_impact	-0,62	medium_impact	0,08	medium_impact	1,16	0,26	0,8	NA	NA	N	0,37	N	0,88	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4945	4945	T	G	MI.13759	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	476	159	I	S	aTc/aGc	-8,26	0	0	benign	0,14	neutral	0,59	neutral	4,51	neutral	-2,8	deleterious	-3,53	medium_impact	2,19	neutral	0,89	neutral	0,49	deleterious	2,4	18,8	0,06	0,35	disease	0,62	disease	0,75	disease	0,58	disease	0,67	3	neutral	0,3	deleterious	0,73	neutral	-3	neutral	0,33	medium_impact	-0,08	medium_impact	0,3	medium_impact	0,7	0,17	0,8	NA	NA	N	0,23	N	0,76	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9172	9172	C	G	MI.1376	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	646	216	L	V	Ctt/Gtt	-14,68	0	0	probably_damaging	0,99	neutral	0,21	neutral	4,4	neutral	-0,59	deleterious	-2,62	low_impact	1,93	neutral	0,74	damaging	0,14	deleterious	3,58	23,2	0,29	0,65	NA	NA	neutral	0,39	neutral	0,31	neutral	0,19	6	deleterious	0,99	neutral	0,11	neutral	-2	deleterious	0,78	low_impact	-2,65	medium_impact	-0,03	medium_impact	0,56	0,6	0,9	48,23	8,94	N	0,32	N	0,87	polymorphism	0,98	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4945	4945	T	C	MI.13760	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	476	159	I	T	aTc/aCc	-8,26	0	0	benign	0,01	neutral	0,54	neutral	4,49	neutral	-2,32	neutral	-2,43	low_impact	1,75	neutral	0,98	neutral	0,95	deleterious	0,2	4,72	0,1	0,4	disease	0,68	neutral	0,43	neutral	0,43	disease	0,58	2	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,15	medium_impact	1,03	medium_impact	0,25	medium_impact	0,33	0,27	0,8	NA	NA	N	0,31	N	0,4	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4946	4946	C	A	MI.13761	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	477	159	I	M	atC/atA	3,02	0,15	0	benign	0,06	neutral	0,31	neutral	4,43	neutral	-2,6	neutral	-0,41	low_impact	1,43	neutral	0,91	neutral	0,95	deleterious	2,25	17,86	0,35	0,5	disease	0,56	neutral	0,35	neutral	0,38	disease	0,6	2	neutral	0,66	deleterious	0,63	neutral	-6	neutral	0,19	medium_impact	0,3	medium_impact	0,02	medium_impact	0,06	0,46	0,8	NA	NA	N	0,46	N	0,68	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4946	4946	C	G	MI.13762	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	477	159	I	M	atC/atG	3,02	0,15	0	benign	0,06	neutral	0,31	neutral	4,43	neutral	-2,6	neutral	-0,41	low_impact	1,43	neutral	0,91	neutral	0,95	deleterious	1,84	15,2	0,35	0,5	disease	0,56	neutral	0,35	neutral	0,38	disease	0,6	2	neutral	0,66	deleterious	0,63	neutral	-6	neutral	0,19	medium_impact	0,3	medium_impact	0,02	medium_impact	0,06	0,46	0,8	NA	NA	N	0,46	N	0,68	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4947	4947	T	A	MI.13763	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	478	160	L	M	Tta/Ata	-8,49	0	0	possibly_damaging	0,46	neutral	0,38	neutral	4,36	deleterious	-3,74	neutral	-1,2	low_impact	1,4	neutral	0,91	neutral	0,92	deleterious	2,16	17,27	0,3	0,45	disease	0,68	neutral	0,23	neutral	0,39	disease	0,55	1	neutral	0,58	neutral	0,46	neutral	-3	deleterious	0,56	medium_impact	-0,73	medium_impact	0,09	medium_impact	0,03	0,61	0,8	NA	NA	N	0,42	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4947	4947	T	G	MI.13764	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	478	160	L	V	Tta/Gta	-8,49	0	0	possibly_damaging	0,79	neutral	0,62	neutral	4,48	neutral	-1,3	neutral	-2,07	medium_impact	1,97	neutral	0,94	neutral	0,71	deleterious	2,3	18,19	0,27	0,45	disease	0,67	neutral	0,41	neutral	0,43	disease	0,62	2	neutral	0,76	neutral	0,42	NA	0	deleterious	0,66	low_impact	-1,32	medium_impact	0,33	medium_impact	0,51	0,59	0,8	NA	NA	N	0,29	N	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4948	4948	T	C	MI.13765	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	479	160	L	S	tTa/tCa	-9,87	0	0	probably_damaging	0,95	neutral	0,71	neutral	4,34	deleterious	-3,96	deleterious	-4,47	low_impact	1,55	neutral	0,91	neutral	0,81	deleterious	2,66	20,6	0,07	0,35	disease	0,83	disease	0,51	neutral	0,49	neutral	0,36	3	neutral	0,95	neutral	0,38	neutral	-2	deleterious	0,75	low_impact	-1,97	medium_impact	0,42	medium_impact	0,16	0,3	0,8	NA	NA	N	0,32	N	0,33	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4948	4948	T	G	MI.13766	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	479	160	L	W	tTa/tGa	-9,87	0	0	probably_damaging	0,99	neutral	0,2	neutral	4,35	deleterious	-6,21	deleterious	-4,95	medium_impact	2,96	neutral	0,82	neutral	0,4	deleterious	3,75	23,3	0,05	0,35	disease	0,97	disease	0,69	disease	0,65	disease	0,72	4	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,8	low_impact	-2,62	medium_impact	-0,13	medium_impact	1,35	0,28	0,8	NA	NA	N	0,34	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4949	4949	A	T	MI.13767	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	480	160	L	F	ttA/ttT	-0,2	0	0	probably_damaging	0,95	neutral	0,75	neutral	4,4	neutral	-2,85	deleterious	-3,27	low_impact	1,85	neutral	0,85	neutral	0,6	deleterious	3,57	23,1	0,19	0,45	disease	0,57	disease	0,53	disease	0,56	disease	0,55	1	neutral	0,95	neutral	0,4	neutral	-2	deleterious	0,7	low_impact	-1,97	medium_impact	0,47	medium_impact	0,41	0,61	0,8	NA	NA	N	0,22	N	0,5	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4949	4949	A	C	MI.13768	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	480	160	L	F	ttA/ttC	-0,2	0	0	probably_damaging	0,95	neutral	0,75	neutral	4,4	neutral	-2,85	deleterious	-3,27	low_impact	1,85	neutral	0,85	neutral	0,6	deleterious	3,48	23,1	0,19	0,45	disease	0,57	disease	0,53	disease	0,56	disease	0,55	1	neutral	0,95	neutral	0,4	neutral	-2	deleterious	0,7	low_impact	-1,97	medium_impact	0,47	medium_impact	0,41	0,61	0,8	NA	NA	N	0,22	N	0,5	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4950	4950	T	G	MI.13769	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	481	161	S	A	Tcc/Gcc	-3,65	0	0	probably_damaging	1	neutral	0,51	neutral	4,37	neutral	-1,94	deleterious	-2,95	medium_impact	3,31	neutral	0,9	neutral	0,57	deleterious	3,56	23,1	0,11	0,4	disease	0,53	disease	0,58	disease	0,65	disease	0,63	3	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,22	medium_impact	1,64	0,39	0,8	NA	NA	N	0,36	N	0,49	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9172	9172	C	T	MI.1377	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	646	216	L	F	Ctt/Ttt	-14,68	0	0	probably_damaging	1	deleterious	0,02	neutral	4,28	neutral	-2,67	deleterious	-3,54	medium_impact	3,25	neutral	0,76	damaging	0,13	deleterious	4,07	23,7	0,39	0,65	NA	NA	disease	0,76	disease	0,56	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,6	medium_impact	-0,66	medium_impact	1,69	0,61	0,9	48,23	8,94	N	0,27	N	0,97	polymorphism	0,9	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4950	4950	T	C	MI.13770	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	481	161	S	P	Tcc/Ccc	-3,65	0	0	probably_damaging	1	neutral	0,2	neutral	4,29	deleterious	-5,73	deleterious	-4,91	high_impact	4,12	neutral	0,74	neutral	0,51	deleterious	3,9	23,5	0,03	0,35	disease	0,89	disease	0,81	disease	0,81	disease	0,66	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	-0,13	high_impact	2,32	0,35	0,8	NA	NA	N	0,47	N	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4950	4950	T	A	MI.13771	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	481	161	S	T	Tcc/Acc	-3,65	0	0	probably_damaging	1	neutral	0,44	neutral	4,51	neutral	-0,36	deleterious	-2,95	medium_impact	2,73	neutral	0,8	neutral	0,46	deleterious	3,69	23,3	0,16	0,45	neutral	0,43	disease	0,58	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0,15	medium_impact	1,15	0,57	0,8	NA	NA	N	0,29	N	0,71	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4951	4951	C	T	MI.13772	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	482	161	S	F	tCc/tTc	7,4	1	0	probably_damaging	1	neutral	0,72	neutral	4,28	deleterious	-6,18	deleterious	-5,89	high_impact	3,77	neutral	0,87	neutral	0,48	deleterious	4,14	23,8	0,03	0,35	neutral	0,4	disease	0,85	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,75	low_impact	-3,54	medium_impact	0,44	high_impact	2,03	0,12	0,8	NA	NA	N	0,55	P	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4951	4951	C	A	MI.13773	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	482	161	S	Y	tCc/tAc	7,4	1	0	probably_damaging	1	neutral	1	neutral	4,29	deleterious	-6,21	deleterious	-5,89	high_impact	4,12	neutral	0,8	neutral	0,41	deleterious	4,12	23,8	0,03	0,35	neutral	0,45	disease	0,83	disease	0,73	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,74	low_impact	-3,54	high_impact	1,87	high_impact	2,32	0,26	0,8	NA	NA	N	0,54	P	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4951	4951	C	G	MI.13774	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	482	161	S	C	tCc/tGc	7,4	1	0	probably_damaging	1	neutral	0,18	neutral	4,28	deleterious	-6,47	deleterious	-4,91	medium_impact	3,08	neutral	0,79	neutral	0,44	deleterious	3,51	23,1	0,03	0,35	disease	0,81	disease	0,76	disease	0,7	disease	0,66	3	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,16	medium_impact	1,45	0,23	0,8	NA	NA	P	0,58	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4953	4953	A	G	MI.13775	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	484	162	I	V	Atc/Gtc	-8,72	0	0	benign	0,02	neutral	0,6	neutral	4,61	neutral	-0,74	neutral	-0,71	neutral_impact	0,46	neutral	0,93	neutral	0,98	neutral	-0,48	0,25	0,55	0,6	neutral	0,36	neutral	0,17	neutral	0,39	neutral	0,29	4	neutral	0,37	deleterious	0,79	neutral	-6	neutral	0,11	medium_impact	0,75	medium_impact	0,31	medium_impact	-0,76	0,36	0,8	NA	NA	N	0,34	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4953	4953	A	C	MI.13776	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	484	162	I	L	Atc/Ctc	-8,72	0	0	benign	0,22	neutral	0,95	neutral	4,64	neutral	-0,19	neutral	-1,91	low_impact	1,31	neutral	0,9	neutral	0,72	deleterious	1,88	15,45	0,27	0,45	neutral	0,42	disease	0,53	neutral	0,46	neutral	0,32	4	neutral	0,14	deleterious	0,87	neutral	-6	neutral	0,33	medium_impact	-0,29	medium_impact	0,92	medium_impact	-0,04	0,48	0,8	NA	NA	N	0,25	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4953	4953	A	T	MI.13777	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	484	162	I	F	Atc/Ttc	-8,72	0	0	possibly_damaging	0,86	neutral	0,73	neutral	4,45	neutral	-2,7	deleterious	-3,89	medium_impact	2,73	neutral	0,9	neutral	0,4	deleterious	3,58	23,2	0,18	0,45	disease	0,57	disease	0,66	disease	0,63	disease	0,69	4	neutral	0,83	neutral	0,44	NA	0	deleterious	0,69	low_impact	-1,52	medium_impact	0,45	medium_impact	1,15	0,37	0,8	NA	NA	N	0,32	N	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4954	4954	T	C	MI.13778	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	485	162	I	T	aTc/aCc	-0,2	0	0	benign	0,06	neutral	0,56	neutral	4,49	neutral	-2,47	deleterious	-4,59	neutral_impact	0,1	neutral	0,92	neutral	0,94	deleterious	0,19	4,62	0,16	0,45	neutral	0,43	neutral	0,13	neutral	0,35	neutral	0,24	5	neutral	0,37	deleterious	0,75	neutral	-6	neutral	0,16	medium_impact	0,3	medium_impact	0,27	low_impact	-1,06	0,23	0,8	NA	NA	N	0,39	N	0,47	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4954	4954	T	G	MI.13779	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	485	162	I	S	aTc/aGc	-0,2	0	0	possibly_damaging	0,58	neutral	0,62	neutral	4,47	neutral	-2,99	deleterious	-5,71	low_impact	1,06	neutral	0,87	neutral	0,59	deleterious	3,9	23,5	0,04	0,35	neutral	0,41	disease	0,67	disease	0,54	neutral	0,46	1	neutral	0,51	deleterious	0,52	neutral	-3	deleterious	0,55	medium_impact	-0,93	medium_impact	0,33	medium_impact	-0,25	0,2	0,8	NA	NA	N	0,24	N	0,86	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9173	9173	T	C	MI.1378	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	647	216	L	P	cTt/cCt	0,36	0,05	0	probably_damaging	1	deleterious	0,01	neutral	4,25	deleterious	-4,92	deleterious	-6,24	high_impact	4,05	neutral	0,74	damaging	0,14	deleterious	4,04	23,7	0,11	0,65	NA	NA	disease	0,87	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,91	low_impact	-3,6	medium_impact	-0,84	high_impact	2,37	0,67	0,9	48,23	8,94	N	0,34	N	1	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4954	4954	T	A	MI.13780	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	485	162	I	N	aTc/aAc	-0,2	0	0	possibly_damaging	0,86	neutral	0,33	neutral	4,42	deleterious	-4,69	deleterious	-6,69	medium_impact	2,38	neutral	0,88	neutral	0,46	deleterious	4,3	24	0,1	0,4	disease	0,76	disease	0,74	disease	0,62	disease	0,7	4	neutral	0,87	neutral	0,24	NA	0	deleterious	0,73	low_impact	-1,52	medium_impact	0,04	medium_impact	0,86	0,2	0,8	NA	NA	N	0,35	N	0,9	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4955	4955	C	A	MI.13781	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	486	162	I	M	atC/atA	0,95	0	0	possibly_damaging	0,86	neutral	0,26	neutral	4,61	neutral	0,5	deleterious	-2,75	low_impact	1,39	neutral	0,91	neutral	0,67	deleterious	3,61	23,2	0,38	0,5	disease	0,61	neutral	0,42	neutral	0,37	disease	0,59	2	neutral	0,89	neutral	0,2	neutral	-3	deleterious	0,67	low_impact	-1,52	medium_impact	-0,04	medium_impact	0,03	0,49	0,8	NA	NA	N	0,43	N	0,63	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4955	4955	C	G	MI.13782	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	486	162	I	M	atC/atG	0,95	0	0	possibly_damaging	0,86	neutral	0,26	neutral	4,61	neutral	0,5	deleterious	-2,75	low_impact	1,39	neutral	0,91	neutral	0,67	deleterious	3,09	22,5	0,38	0,5	disease	0,61	neutral	0,42	neutral	0,37	disease	0,59	2	neutral	0,89	neutral	0,2	neutral	-3	deleterious	0,67	low_impact	-1,52	medium_impact	-0,04	medium_impact	0,03	0,49	0,8	NA	NA	N	0,43	N	0,63	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4956	4956	A	C	MI.13783	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	487	163	M	L	Ata/Cta	-12,17	0	0	benign	0	neutral	0,94	neutral	5,25	neutral	3,58	neutral	-0,83	neutral_impact	-1,54	neutral	0,96	neutral	0,99	neutral	-1,33	0	0,28	0,45	neutral	0,49	neutral	0,26	neutral	0,3	neutral	0,4	2	neutral	0,05	deleterious	0,97	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,87	low_impact	-2,44	0,26	0,8	0,58	7,37	N	0,34	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4956	4956	A	G	MI.13784	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	487	163	M	V	Ata/Gta	-12,17	0	0	benign	0,08	neutral	0,61	neutral	4,72	neutral	1,14	neutral	-2,06	neutral_impact	-0,27	neutral	0,94	neutral	0,93	neutral	-0,24	0,89	0,23	0,45	neutral	0,41	disease	0,5	neutral	0,4	neutral	0,22	6	neutral	0,3	deleterious	0,77	neutral	-6	neutral	0,18	medium_impact	0,17	medium_impact	0,32	low_impact	-1,37	0,29	0,8	0,58	7,37	N	0,28	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4956	4956	A	T	MI.13785	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	487	163	M	L	Ata/Tta	-12,17	0	0	benign	0	neutral	0,94	neutral	5,25	neutral	3,58	neutral	-0,83	neutral_impact	-1,54	neutral	0,96	neutral	0,99	neutral	-1,26	0,01	0,28	0,45	neutral	0,49	neutral	0,26	neutral	0,3	neutral	0,4	2	neutral	0,05	deleterious	0,97	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,87	low_impact	-2,44	0,26	0,8	0,58	7,37	N	0,33	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4957	4957	T	A	MI.13786	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	488	163	M	K	aTa/aAa	-5,04	0	0	benign	0,17	neutral	0,37	neutral	4,58	deleterious	-3,36	deleterious	-4,38	low_impact	1,75	neutral	0,86	neutral	0,37	deleterious	2,03	16,43	0,04	0,35	neutral	0,45	disease	0,76	disease	0,66	disease	0,72	4	neutral	0,56	deleterious	0,6	neutral	-6	neutral	0,33	medium_impact	-0,17	medium_impact	0,08	medium_impact	0,33	0,17	0,8	0,58	7,37	N	0,28	N	0,62	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4957	4957	T	C	MI.13787	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	488	163	M	T	aTa/aCa	-5,04	0	0	benign	0,17	neutral	0,52	neutral	4,59	neutral	-1,84	deleterious	-3,8	neutral_impact	0,5	neutral	0,93	neutral	0,78	neutral	1,01	10,73	0,11	0,4	neutral	0,41	neutral	0,5	disease	0,57	neutral	0,42	2	neutral	0,38	deleterious	0,68	neutral	-6	neutral	0,27	medium_impact	-0,17	medium_impact	0,23	medium_impact	-0,72	0,11	0,8	0,58	7,37	N	0,3	N	0,32	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4958	4958	A	T	MI.13788	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	489	163	M	I	atA/atT	0,95	0	0,08	benign	0,05	neutral	0,54	neutral	5	neutral	2,79	neutral	-1,85	neutral_impact	-0,42	neutral	0,87	neutral	0,97	deleterious	0,2	4,71	0,27	0,45	neutral	0,36	neutral	0,45	neutral	0,36	neutral	0,42	2	neutral	0,41	deleterious	0,75	neutral	-6	neutral	0,18	medium_impact	0,37	medium_impact	0,25	low_impact	-1,5	0,36	0,8	0,58	7,37	N	0,37	N	0,16	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4958	4958	A	C	MI.13789	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	489	163	M	I	atA/atC	0,95	0	0,08	benign	0,05	neutral	0,54	neutral	5	neutral	2,79	neutral	-1,85	neutral_impact	-0,42	neutral	0,87	neutral	0,97	deleterious	0,09	3,48	0,27	0,45	neutral	0,36	neutral	0,45	neutral	0,36	neutral	0,42	2	neutral	0,41	deleterious	0,75	neutral	-6	neutral	0,18	medium_impact	0,37	medium_impact	0,25	low_impact	-1,5	0,36	0,8	0,58	7,37	N	0,37	N	0,16	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9173	9173	T	A	MI.1379	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	647	216	L	H	cTt/cAt	0,36	0,05	0	probably_damaging	1	deleterious	0,02	neutral	4,25	deleterious	-4,88	deleterious	-6,23	high_impact	4,05	neutral	0,76	damaging	0,13	deleterious	4,36	24,1	0,14	0,65	NA	NA	disease	0,83	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,6	medium_impact	-0,66	high_impact	2,37	0,58	0,9	48,23	8,94	N	0,33	N	0,97	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4959	4959	G	T	MI.13790	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	490	164	A	S	Gca/Tca	-3,42	0	0,02	benign	0,29	neutral	0,45	neutral	4,62	neutral	-1,74	neutral	-1,48	neutral_impact	0,72	neutral	0,86	neutral	0,64	deleterious	1,93	15,76	0,23	0,45	neutral	0,37	neutral	0,36	neutral	0,45	neutral	0,44	1	neutral	0,46	deleterious	0,58	neutral	-6	neutral	0,36	medium_impact	-0,44	medium_impact	0,16	medium_impact	-0,54	0,35	0,8	NA	NA	N	0,31	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4959	4959	G	C	MI.13791	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	490	164	A	P	Gca/Cca	-3,42	0	0,02	possibly_damaging	0,75	neutral	0,22	neutral	4,59	deleterious	-3,75	neutral	-2,23	low_impact	1,07	neutral	0,86	neutral	0,38	deleterious	3,47	23	0,06	0,35	disease	0,89	disease	0,8	disease	0,62	disease	0,7	4	neutral	0,85	neutral	0,24	neutral	-3	deleterious	0,78	low_impact	-1,23	medium_impact	-0,1	medium_impact	-0,24	0,34	0,8	NA	NA	N	0,28	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4959	4959	G	A	MI.13792	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	490	164	A	T	Gca/Aca	-3,42	0	0,02	benign	0,03	neutral	0,42	neutral	4,63	neutral	-0,75	neutral	-0,36	neutral_impact	-0,36	neutral	0,94	neutral	0,84	neutral	1,23	11,92	0,17	0,45	neutral	0,4	neutral	0,29	neutral	0,24	neutral	0,46	1	neutral	0,55	deleterious	0,7	neutral	-6	neutral	0,13	medium_impact	0,59	medium_impact	0,13	low_impact	-1,45	0,56	0,8	NA	NA	N	0,37	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4960	4960	C	T	MI.13793	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	491	164	A	V	gCa/gTa	-5,04	0	0,01	benign	0,01	neutral	0,52	neutral	4,78	neutral	1,04	neutral	2,91	neutral_impact	-1,65	neutral	0,96	neutral	0,98	deleterious	0,24	5,08	0,16	0,45	disease	0,5	neutral	0,15	neutral	0,2	neutral	0,17	7	neutral	0,47	deleterious	0,76	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,23	low_impact	-2,53	0,52	0,8	NA	NA	N	0,34	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4960	4960	C	A	MI.13794	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	491	164	A	E	gCa/gAa	-5,04	0	0,01	possibly_damaging	0,57	neutral	0,33	neutral	4,59	deleterious	-3,49	neutral	-2,23	low_impact	1,42	neutral	0,91	neutral	0,61	deleterious	2,86	21,7	0,05	0,35	disease	0,87	disease	0,72	disease	0,6	disease	0,68	4	neutral	0,68	neutral	0,38	neutral	-3	deleterious	0,63	medium_impact	-0,91	medium_impact	0,04	medium_impact	0,05	0,31	0,8	NA	NA	N	0,35	N	0,55	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4960	4960	C	G	MI.13795	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	491	164	A	G	gCa/gGa	-5,04	0	0,01	possibly_damaging	0,44	neutral	0,36	neutral	4,6	neutral	-2,35	deleterious	-3,02	low_impact	1,42	neutral	0,89	neutral	0,6	deleterious	2,21	17,55	0,17	0,45	disease	0,69	neutral	0,35	neutral	0,45	disease	0,62	2	neutral	0,59	neutral	0,46	neutral	-3	deleterious	0,5	medium_impact	-0,7	medium_impact	0,07	medium_impact	0,05	0,48	0,8	NA	NA	N	0,42	N	0,56	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4962	4962	G	C	MI.13796	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	493	165	G	R	Ggc/Cgc	-11,71	0	0	probably_damaging	1	neutral	0,35	neutral	4,3	deleterious	-6,19	deleterious	-7,86	high_impact	4,13	neutral	0,81	damaging	0,09	deleterious	3,94	23,5	0,01	0,35	disease	0,84	disease	0,92	disease	0,84	disease	0,66	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-3,54	medium_impact	0,06	high_impact	2,33	0,68	0,85	NA	NA	N	0,42	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4962	4962	G	A	MI.13797	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	493	165	G	S	Ggc/Agc	-11,71	0	0	probably_damaging	1	neutral	0,44	neutral	4,38	deleterious	-4,5	deleterious	-5,89	medium_impact	2,37	neutral	0,78	damaging	0,13	deleterious	4,15	23,8	0,03	0,35	disease	0,87	disease	0,87	disease	0,68	disease	0,62	2	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,87	low_impact	-3,54	medium_impact	0,15	medium_impact	0,85	0,73	0,85	NA	NA	N	0,28	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4962	4962	G	T	MI.13798	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	493	165	G	C	Ggc/Tgc	-11,71	0	0	probably_damaging	1	neutral	0,18	neutral	4,28	deleterious	-6,89	deleterious	-8,84	high_impact	4,13	neutral	0,78	damaging	0,08	deleterious	4,12	23,8	0,02	0,35	disease	0,98	disease	0,93	disease	0,75	disease	0,65	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,54	medium_impact	-0,16	high_impact	2,33	0,24	0,8	NA	NA	N	0,36	N	0,96	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4963	4963	G	C	MI.13799	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	494	165	G	A	gGc/gCc	7,17	1	0	probably_damaging	1	neutral	0,51	neutral	4,5	neutral	-2,53	deleterious	-5,89	medium_impact	3,16	neutral	0,87	damaging	0,13	deleterious	3,1	22,5	0,03	0,35	disease	0,85	disease	0,79	disease	0,66	disease	0,64	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	0,22	medium_impact	1,52	0,39	0,8	NA	NA	P	0,57	P	0,74	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8591	8591	T	G	MI.138	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	65	22	L	R	cTg/cGg	-5,89	0	0	possibly_damaging	0,8	deleterious	0,01	neutral	4,12	deleterious	-3,6	deleterious	-4,39	medium_impact	3,46	neutral	0,77	neutral	0,38	deleterious	3,78	23,4	0,15	0,65	disease	0,84	disease	0,84	disease	0,7	disease	0,8	6	deleterious	0,99	neutral	0,11	deleterious	4	deleterious	0,79	low_impact	-1,33	medium_impact	-0,84	medium_impact	1,87	0,61	0,9	25,22	20,33	N	0,31	N	0,45	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9173	9173	T	G	MI.1380	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	647	216	L	R	cTt/cGt	0,36	0,05	0	probably_damaging	1	neutral	0,14	neutral	4,31	deleterious	-4	deleterious	-5,35	high_impact	4,05	neutral	0,78	damaging	0,13	deleterious	4,34	24	0,11	0,65	NA	NA	disease	0,9	disease	0,67	disease	0,75	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,15	high_impact	2,37	0,56	0,9	48,23	8,94	N	0,33	N	0,99	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4963	4963	G	T	MI.13800	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	494	165	G	V	gGc/gTc	7,17	1	0	probably_damaging	1	neutral	0,52	neutral	4,34	deleterious	-4,77	deleterious	-8,84	high_impact	4,13	neutral	0,69	damaging	0,1	deleterious	3,74	23,3	0,02	0,35	disease	0,93	disease	0,91	disease	0,77	disease	0,61	2	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	0,23	high_impact	2,33	0,19	0,8	NA	NA	P	0,67	P	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4963	4963	G	A	MI.13801	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	494	165	G	D	gGc/gAc	7,17	1	0	probably_damaging	1	neutral	0,2	neutral	4,29	deleterious	-6,7	deleterious	-6,88	high_impact	4,13	neutral	0,82	damaging	0,1	deleterious	3,82	23,4	0,02	0,35	disease	0,83	disease	0,91	disease	0,83	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,54	medium_impact	-0,13	high_impact	2,33	0,12	0,8	NA	NA	P	0,66	P	0,95	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4965	4965	A	T	MI.13802	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	496	166	S	C	Agt/Tgt	-5,73	0	0	probably_damaging	0,97	neutral	0,17	neutral	4,09	deleterious	-6,19	deleterious	-3,21	medium_impact	2,22	neutral	0,82	neutral	0,49	deleterious	3,42	23	0,06	0,35	disease	0,94	disease	0,76	disease	0,59	disease	0,68	4	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,84	low_impact	-2,18	medium_impact	-0,17	medium_impact	0,72	0,35	0,8	2,59	7,82	N	0,32	N	0,65	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4965	4965	A	C	MI.13803	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	496	166	S	R	Agt/Cgt	-5,73	0	0	probably_damaging	0,93	neutral	0,35	neutral	4,1	deleterious	-4,8	neutral	-2,36	medium_impact	2,22	neutral	0,82	neutral	0,53	deleterious	3,66	23,2	0,03	0,35	disease	0,83	disease	0,89	disease	0,71	disease	0,68	4	neutral	0,93	neutral	0,21	deleterious	1	deleterious	0,88	low_impact	-1,83	medium_impact	0,06	medium_impact	0,72	0,42	0,8	2,59	7,82	N	0,27	N	0,62	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4965	4965	A	G	MI.13804	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	496	166	S	G	Agt/Ggt	-5,73	0	0	benign	0,04	neutral	0,56	neutral	4,31	neutral	-1,44	neutral	4,57	neutral_impact	-1,76	neutral	0,86	neutral	0,92	neutral	-1,1	0,01	0,14	0,4	disease	0,63	neutral	0,09	neutral	0,25	neutral	0,32	4	neutral	0,39	deleterious	0,76	neutral	-6	neutral	0,18	medium_impact	0,47	medium_impact	0,27	low_impact	-2,63	0,4	0,8	2,59	7,82	N	0,29	N	0	polymorphism	1	0,01	rs879150535	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4966	4966	G	A	MI.13805	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	497	166	S	N	aGt/aAt	4,86	1	0	possibly_damaging	0,81	neutral	0,36	neutral	4,16	neutral	-2,97	neutral	-0,4	low_impact	1,53	neutral	0,85	neutral	0,66	deleterious	1,82	15,1	0,4	0,5	disease	0,78	disease	0,75	disease	0,59	disease	0,68	4	neutral	0,83	neutral	0,28	neutral	-3	deleterious	0,79	low_impact	-1,37	medium_impact	0,07	medium_impact	0,14	0,44	0,8	2,59	7,82	P	0,55	P	0,35	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4966	4966	G	C	MI.13806	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	497	166	S	T	aGt/aCt	4,86	1	0	possibly_damaging	0,71	neutral	0,4	neutral	4,23	neutral	-2,11	neutral	-2,1	low_impact	1,25	neutral	0,9	neutral	0,7	neutral	1,79	14,95	0,2	0,45	neutral	0,43	neutral	0,46	disease	0,59	neutral	0,48	0	neutral	0,73	neutral	0,35	neutral	-3	deleterious	0,68	low_impact	-1,15	medium_impact	0,11	medium_impact	-0,09	0,55	0,8	2,59	7,82	P	0,6	P	0,37	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4966	4966	G	T	MI.13807	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	497	166	S	I	aGt/aTt	4,86	1	0	probably_damaging	0,95	neutral	0,41	neutral	4,09	deleterious	-5,66	deleterious	-4,19	low_impact	1,88	neutral	0,85	neutral	0,6	deleterious	3,96	23,6	0,04	0,35	disease	0,89	disease	0,83	disease	0,61	disease	0,66	3	neutral	0,95	neutral	0,23	neutral	-2	deleterious	0,87	low_impact	-1,97	medium_impact	0,12	medium_impact	0,44	0,28	0,8	2,59	7,82	P	0,55	P	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4968	4968	T	G	MI.13808	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	499	167	W	G	Tga/Gga	-10,56	0	0	probably_damaging	1	neutral	0,41	neutral	4,63	neutral	-1,75	deleterious	-12,77	high_impact	3,5	damaging	0,52	damaging	0,05	deleterious	3,86	23,5	0,05	0,35	disease	0,84	disease	0,86	disease	0,8	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,12	medium_impact	1,8	0,13	0,8	NA	NA	N	0,43	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4968	4968	T	C	MI.13809	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	499	167	W	R	Tga/Cga	-10,56	0	0	probably_damaging	1	neutral	0,36	neutral	4,6	neutral	-2,03	deleterious	-13,75	high_impact	3,85	damaging	0,43	damaging	0,04	deleterious	3,54	23,1	0,04	0,35	disease	0,82	disease	0,92	disease	0,85	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	0,07	high_impact	2,1	0,09	0,8	NA	NA	P	0,52	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9175	9175	C	G	MI.1381	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	649	217	L	V	Cta/Gta	-11,67	0	0	probably_damaging	0,99	deleterious	0,01	neutral	2,23	deleterious	-6,6	deleterious	-2,67	high_impact	4,01	damaging	0,36	neutral	0,51	deleterious	3,52	23,1	0,2	0,65	NA	NA	disease	0,62	disease	0,8	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,65	medium_impact	-0,84	high_impact	2,34	0,68	0,9	50	9,01	P	0,61	P	0,87	polymorphism	0,82	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4969	4969	G	T	MI.13810	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	500	167	W	L	tGa/tTa	5,55	1	0	probably_damaging	1	neutral	0,71	neutral	4,99	neutral	2,94	deleterious	-12,77	low_impact	1,46	damaging	0,58	damaging	0,03	deleterious	4,19	23,9	0,09	0,35	disease	0,57	disease	0,87	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,82	low_impact	-3,54	medium_impact	0,42	medium_impact	0,09	0,09	0,8	NA	NA	N	0,46	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4969	4969	G	C	MI.13811	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	500	167	W	S	tGa/tCa	5,55	1	0	probably_damaging	1	neutral	0,47	neutral	4,68	neutral	-0,82	deleterious	-13,75	high_impact	3,85	damaging	0,48	damaging	0,05	deleterious	3,97	23,6	0,06	0,35	disease	0,74	disease	0,93	disease	0,8	disease	0,71	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,18	high_impact	2,1	0,14	0,8	NA	NA	P	0,62	P	0,94	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4970	4970	A	C	MI.13812	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	501	167	W	C	tgA/tgC	7,17	1	0	probably_damaging	1	neutral	0,17	neutral	4,6	neutral	-2,11	deleterious	-12,77	high_impact	3,5	damaging	0,55	damaging	0,03	deleterious	3,98	23,6	0,05	0,35	neutral	0,46	disease	0,92	disease	0,83	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,17	medium_impact	1,8	0,11	0,8	NA	NA	P	0,56	P	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4970	4970	A	T	MI.13813	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	501	167	W	C	tgA/tgT	7,17	1	0	probably_damaging	1	neutral	0,17	neutral	4,6	neutral	-2,11	deleterious	-12,77	high_impact	3,5	damaging	0,55	damaging	0,03	deleterious	4,1	23,7	0,05	0,35	neutral	0,46	disease	0,92	disease	0,83	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,17	medium_impact	1,8	0,11	0,8	NA	NA	P	0,57	P	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4971	4971	G	A	MI.13814	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	502	168	G	S	Ggt/Agt	2,1	1	0	probably_damaging	1	neutral	0,44	neutral	4,56	neutral	-0,93	deleterious	-5,89	medium_impact	2,31	neutral	0,84	damaging	0,08	deleterious	4,15	23,8	0,11	0,4	neutral	0,36	disease	0,85	disease	0,59	disease	0,54	1	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	0,15	medium_impact	0,8	0,75	0,85	NA	NA	N	0,37	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4971	4971	G	T	MI.13815	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	502	168	G	C	Ggt/Tgt	2,1	1	0	probably_damaging	1	neutral	0,17	neutral	4,55	neutral	-2,66	deleterious	-8,84	high_impact	3,94	neutral	0,8	damaging	0,08	deleterious	4,22	23,9	0,04	0,35	disease	0,85	disease	0,94	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	-0,17	high_impact	2,17	0,19	0,8	NA	NA	N	0,51	P	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4971	4971	G	C	MI.13816	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	502	168	G	R	Ggt/Cgt	2,1	1	0	probably_damaging	1	neutral	0,36	neutral	4,5	neutral	-2,48	deleterious	-7,85	high_impact	3,94	neutral	0,79	damaging	0,07	deleterious	3,98	23,6	0,03	0,35	neutral	0,47	disease	0,93	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,07	high_impact	2,17	0,51	0,8	NA	NA	N	0,52	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4972	4972	G	T	MI.13817	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	503	168	G	V	gGt/gTt	2,56	1	0	probably_damaging	1	neutral	0,51	neutral	4,67	neutral	0,63	deleterious	-8,84	medium_impact	2,9	neutral	0,84	damaging	0,09	deleterious	3,74	23,3	0,05	0,35	disease	0,57	disease	0,91	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0,22	medium_impact	1,3	0,19	0,8	NA	NA	N	0,41	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4972	4972	G	A	MI.13818	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	503	168	G	D	gGt/gAt	2,56	1	0	probably_damaging	1	neutral	0,2	neutral	4,49	deleterious	-4,38	deleterious	-6,87	high_impact	3,94	neutral	0,82	damaging	0,07	deleterious	3,75	23,3	0,03	0,35	neutral	0,24	disease	0,93	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	-0,13	high_impact	2,17	0,17	0,8	NA	NA	N	0,54	P	0,95	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4972	4972	G	C	MI.13819	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	503	168	G	A	gGt/gCt	2,56	1	0	probably_damaging	1	neutral	0,53	neutral	4,62	neutral	0,47	deleterious	-5,89	medium_impact	2,11	neutral	0,87	damaging	0,15	deleterious	3,06	22,4	0,16	0,45	neutral	0,42	disease	0,77	disease	0,61	neutral	0,4	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,24	medium_impact	0,63	0,42	0,8	NA	NA	N	0,36	N	0,74	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9175	9175	C	A	MI.1382	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	649	217	L	M	Cta/Ata	-11,67	0	0	probably_damaging	1	deleterious	0	neutral	2,21	deleterious	-7,14	neutral	-1,78	high_impact	4,57	damaging	0,43	neutral	0,6	deleterious	3,86	23,5	0,16	0,65	NA	NA	disease	0,6	disease	0,77	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,6	low_impact	-1,4	high_impact	2,82	0,58	0,9	50	9,01	P	0,62	P	0,96	polymorphism	0,85	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4974	4974	G	T	MI.13820	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	505	169	G	W	Gga/Tga	-10,1	0	0	probably_damaging	1	neutral	0,19	neutral	4,33	deleterious	-4,91	deleterious	-7,84	high_impact	4,09	neutral	0,75	damaging	0,18	deleterious	4,48	24,2	0,03	0,35	disease	0,86	disease	0,94	disease	0,76	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	-0,14	high_impact	2,3	0,08	0,8	NA	NA	N	0,39	N	0,99	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4974	4974	G	C	MI.13821	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	505	169	G	R	Gga/Cga	-10,1	0	0	probably_damaging	1	neutral	0,36	neutral	4,35	deleterious	-3,03	deleterious	-7,84	high_impact	3,75	neutral	0,77	damaging	0,18	deleterious	3,96	23,6	0,03	0,35	disease	0,61	disease	0,93	disease	0,8	disease	0,73	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	0,07	high_impact	2,01	0,59	0,8	NA	NA	N	0,41	N	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4975	4975	G	T	MI.13822	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	506	169	G	V	gGa/gTa	7,17	1	0	probably_damaging	1	neutral	0,51	neutral	4,42	neutral	-1,18	deleterious	-8,82	high_impact	4,09	neutral	0,65	damaging	0,22	deleterious	3,76	23,3	0,03	0,35	neutral	0,43	disease	0,93	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	0,22	high_impact	2,3	0,2	0,8	NA	NA	P	0,63	P	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4975	4975	G	A	MI.13823	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	506	169	G	E	gGa/gAa	7,17	1	0	probably_damaging	1	neutral	0,28	neutral	4,36	neutral	-2,83	deleterious	-7,84	high_impact	4,09	neutral	0,73	damaging	0,22	deleterious	3,84	23,4	0,03	0,35	neutral	0,39	disease	0,93	disease	0,81	disease	0,72	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	-0,02	high_impact	2,3	0,23	0,8	NA	NA	P	0,7	P	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4975	4975	G	C	MI.13824	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	506	169	G	A	gGa/gCa	7,17	1	0	probably_damaging	1	neutral	0,53	neutral	4,74	neutral	3,06	deleterious	-5,88	medium_impact	2,53	neutral	0,73	neutral	0,34	deleterious	3,08	22,5	0,11	0,4	neutral	0,23	disease	0,84	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,24	medium_impact	0,99	0,46	0,8	NA	NA	N	0,51	P	0,74	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4977	4977	T	A	MI.13825	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	508	170	L	M	Tta/Ata	-5,73	0	0	probably_damaging	1	neutral	0,25	neutral	4,12	deleterious	-3,54	neutral	-1,96	medium_impact	2,23	neutral	0,95	damaging	0,14	deleterious	3,59	23,2	0,18	0,45	NA	NA	disease	0,7	disease	0,59	disease	0,64	3	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,06	medium_impact	0,73	0,58	0,8	NA	NA	N	0,39	N	0,88	polymorphism	1	0,02	rs28357981	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4977	4977	T	G	MI.13826	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	508	170	L	V	Tta/Gta	-5,73	0	0	probably_damaging	1	neutral	0,53	neutral	4,11	neutral	-2,17	deleterious	-2,94	medium_impact	2,69	neutral	0,82	damaging	0,13	deleterious	3,43	23	0,13	0,4	NA	NA	disease	0,71	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0,24	medium_impact	1,12	0,58	0,8	NA	NA	N	0,18	N	0,77	polymorphism	1	0,06	rs28357981	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4978	4978	T	G	MI.13827	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	509	170	L	W	tTa/tGa	0,03	0	0	probably_damaging	1	neutral	0,19	neutral	4,04	deleterious	-6,04	deleterious	-5,88	medium_impact	2,65	neutral	0,87	damaging	0,1	deleterious	3,74	23,3	0,03	0,35	NA	NA	disease	0,82	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,87	low_impact	-3,54	medium_impact	-0,14	medium_impact	1,09	0,19	0,8	NA	NA	N	0,34	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4978	4978	T	C	MI.13828	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	509	170	L	S	tTa/tCa	0,03	0	0	probably_damaging	1	neutral	0,52	neutral	4,05	deleterious	-4,64	deleterious	-5,88	medium_impact	3,42	neutral	0,85	damaging	0,14	deleterious	3,75	23,3	0,02	0,35	NA	NA	disease	0,83	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,88	low_impact	-3,54	medium_impact	0,23	medium_impact	1,73	0,25	0,8	NA	NA	N	0,26	N	0,96	polymorphism	1	0,11	rs879210481	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4979	4979	A	T	MI.13829	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	510	170	L	F	ttA/ttT	7,4	0,95	0	probably_damaging	1	neutral	0,7	neutral	4,09	deleterious	-3,19	deleterious	-3,92	medium_impact	2,23	neutral	0,85	damaging	0,1	deleterious	3,58	23,2	0,08	0,35	NA	NA	disease	0,78	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	0,41	medium_impact	0,73	0,57	0,8	NA	NA	N	0,43	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9176	9176	T	A	MI.1383	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	650	217	L	Q	cTa/cAa	-0,1	0	0,01	probably_damaging	1	deleterious	0	neutral	2,16	deleterious	-9,42	deleterious	-5,35	high_impact	4,57	damaging	0,41	neutral	0,45	deleterious	4,13	23,8	0,11	0,65	NA	NA	disease	0,82	disease	0,79	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,82	0,61	0,9	50	9,01	P	0,66	P	0,98	disease_causing	0,88	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4979	4979	A	C	MI.13830	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	510	170	L	F	ttA/ttC	7,4	0,95	0	probably_damaging	1	neutral	0,7	neutral	4,09	deleterious	-3,19	deleterious	-3,92	medium_impact	2,23	neutral	0,85	damaging	0,1	deleterious	3,44	23	0,08	0,35	NA	NA	disease	0,78	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	0,41	medium_impact	0,73	0,57	0,8	NA	NA	N	0,43	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4980	4980	A	T	MI.13831	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	511	171	N	Y	Aac/Tac	-5,27	0	0	probably_damaging	1	neutral	0,75	neutral	4,53	neutral	-2	deleterious	-7,84	high_impact	3,75	neutral	0,68	damaging	0,05	deleterious	3,68	23,3	0,07	0,35	disease	0,78	disease	0,91	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,88	low_impact	-3,54	medium_impact	0,47	high_impact	2,01	0,19	0,8	NA	NA	N	0,32	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4980	4980	A	C	MI.13832	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	511	171	N	H	Aac/Cac	-5,27	0	0	probably_damaging	1	neutral	0,48	neutral	4,52	neutral	-2,52	deleterious	-4,9	high_impact	3,75	neutral	0,74	damaging	0,04	deleterious	3,05	22,4	0,2	0,45	disease	0,79	disease	0,84	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,19	high_impact	2,01	0,2	0,8	NA	NA	N	0,29	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4980	4980	A	G	MI.13833	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	511	171	N	D	Aac/Gac	-5,27	0	0	probably_damaging	1	neutral	0,64	neutral	4,55	neutral	-1,56	deleterious	-4,9	high_impact	3,75	neutral	0,71	damaging	0,04	deleterious	3,78	23,4	0,27	0,45	disease	0,64	disease	0,82	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,35	high_impact	2,01	0,25	0,8	NA	NA	N	0,25	N	0,92	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4981	4981	A	G	MI.13834	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	512	171	N	S	aAc/aGc	8,55	1	0	probably_damaging	1	neutral	0,93	neutral	4,65	neutral	0,01	deleterious	-4,9	medium_impact	2,9	neutral	0,73	damaging	0,08	deleterious	2,95	22,1	0,28	0,45	disease	0,62	disease	0,83	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,47	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	0,83	medium_impact	1,3	0,21	0,8	NA	NA	N	0,46	N	0,8	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4981	4981	A	T	MI.13835	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	512	171	N	I	aAc/aTc	8,55	1	0	probably_damaging	1	neutral	0,45	neutral	4,53	neutral	-2,35	deleterious	-8,82	medium_impact	2,94	neutral	0,74	damaging	0,05	deleterious	3,8	23,4	0,09	0,4	disease	0,83	disease	0,93	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,89	low_impact	-3,54	medium_impact	0,16	medium_impact	1,33	0,13	0,8	NA	NA	P	0,54	P	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4981	4981	A	C	MI.13836	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	512	171	N	T	aAc/aCc	8,55	1	0	probably_damaging	1	neutral	0,77	neutral	4,64	neutral	-0,02	deleterious	-5,88	medium_impact	2,86	neutral	0,74	damaging	0,05	deleterious	3,31	22,9	0,18	0,45	disease	0,63	disease	0,85	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	0,5	medium_impact	1,26	0,2	0,8	NA	NA	N	0,48	N	0,92	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4982	4982	C	A	MI.13837	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	513	171	N	K	aaC/aaA	8,55	1	0	probably_damaging	1	neutral	0,96	neutral	4,61	neutral	-0,34	deleterious	-5,88	high_impact	3,54	neutral	0,73	damaging	0,04	deleterious	4,45	24,2	0,2	0,45	disease	0,52	disease	0,89	disease	0,71	disease	0,71	4	deleterious	1	deleterious	0,48	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	0,98	medium_impact	1,84	0,35	0,8	NA	NA	N	0,5	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4982	4982	C	G	MI.13838	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	513	171	N	K	aaC/aaG	8,55	1	0	probably_damaging	1	neutral	0,96	neutral	4,61	neutral	-0,34	deleterious	-5,88	high_impact	3,54	neutral	0,73	damaging	0,04	deleterious	4,01	23,6	0,2	0,45	disease	0,52	disease	0,89	disease	0,71	disease	0,71	4	deleterious	1	deleterious	0,48	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	0,98	medium_impact	1,84	0,35	0,8	NA	NA	N	0,49	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4983	4983	C	G	MI.13839	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	514	172	Q	E	Caa/Gaa	-0,2	0,71	0	probably_damaging	0,99	neutral	0,27	neutral	4,15	deleterious	-4,12	deleterious	-2,93	medium_impact	2,8	neutral	0,82	neutral	0,42	deleterious	3,06	22,4	0,12	0,4	neutral	0,47	disease	0,81	disease	0,78	disease	0,7	4	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,85	low_impact	-2,62	medium_impact	-0,03	medium_impact	1,21	0,34	0,8	NA	NA	N	0,36	N	0,9	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9176	9176	T	C	MI.1384	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	650	217	L	P	cTa/cCa	-0,1	0	0,01	probably_damaging	1	deleterious	0	neutral	2,16	deleterious	-9,53	deleterious	-6,26	high_impact	4,22	damaging	0,06	neutral	0,44	deleterious	4	23,6	0,12	0,65	NA	NA	disease	0,8	disease	0,84	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,6	low_impact	-1,4	high_impact	2,52	0,54	0,9	50	9,01	P	0,92	P	1	disease_causing_automatic	1	0,42	rs199476135	Pathogenic|Pathogenic,Pathogenic	Striatonigral_degeneration,_infantile,_mitochondrial|Leigh_syndrome,Leigh_syndrome	RCV000010278.4|RCV000010279.5,RCV000010285.5	MedGen:OMIM|MedGen:OMIM:Orphanet:SNOMED_CT,MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	T9176C	FBSN/Leigh Disease	+	+	Cfrm	18
chrM	4983	4983	C	A	MI.13840	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	514	172	Q	K	Caa/Aaa	-0,2	0,71	0	probably_damaging	0,99	neutral	0,31	neutral	4,11	deleterious	-4,04	deleterious	-3,91	high_impact	3,77	neutral	0,79	neutral	0,38	deleterious	4,05	23,7	0,07	0,35	disease	0,59	disease	0,9	disease	0,82	disease	0,73	5	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,87	low_impact	-2,62	medium_impact	0,02	high_impact	2,03	0,41	0,8	NA	NA	N	0,45	N	0,97	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4984	4984	A	G	MI.13841	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	515	172	Q	R	cAa/cGa	5,55	1	0	probably_damaging	0,99	neutral	0,37	neutral	4,07	deleterious	-4,7	deleterious	-3,91	high_impact	4,12	neutral	0,78	neutral	0,39	deleterious	3,49	23,1	0,08	0,35	disease	0,69	disease	0,89	disease	0,83	disease	0,74	5	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,89	low_impact	-2,62	medium_impact	0,08	high_impact	2,32	0,3	0,8	NA	NA	P	0,7	P	0,87	polymorphism	0,99	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4984	4984	A	T	MI.13842	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	515	172	Q	L	cAa/cTa	5,55	1	0	probably_damaging	1	neutral	0,69	neutral	4,08	deleterious	-5,99	deleterious	-6,85	medium_impact	3,42	neutral	0,76	neutral	0,42	deleterious	3,82	23,4	0,03	0,35	disease	0,68	disease	0,91	disease	0,76	disease	0,72	4	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,89	low_impact	-3,54	medium_impact	0,4	medium_impact	1,73	0,25	0,8	NA	NA	N	0,56	P	0,96	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4984	4984	A	C	MI.13843	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	515	172	Q	P	cAa/cCa	5,55	1	0	probably_damaging	1	neutral	0,2	neutral	4,03	deleterious	-6,63	deleterious	-5,87	high_impact	4,12	neutral	0,87	neutral	0,45	deleterious	3,34	22,9	0,02	0,35	disease	0,84	disease	0,91	disease	0,84	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,92	low_impact	-3,54	medium_impact	-0,13	high_impact	2,32	0,15	0,8	NA	NA	P	0,7	P	0,96	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4985	4985	A	T	MI.13844	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	516	172	Q	H	caA/caT	5,55	1	0	probably_damaging	1	neutral	0,54	neutral	4,04	deleterious	-6,17	deleterious	-4,89	medium_impact	2,96	neutral	0,81	neutral	0,34	deleterious	3,57	23,2	0,06	0,35	disease	0,82	disease	0,84	disease	0,84	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,89	low_impact	-3,54	medium_impact	0,25	medium_impact	1,35	0,51	0,8	NA	NA	P	0,57	P	0,97	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4985	4985	A	C	MI.13845	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	516	172	Q	H	caA/caC	5,55	1	0	probably_damaging	1	neutral	0,54	neutral	4,04	deleterious	-6,17	deleterious	-4,89	medium_impact	2,96	neutral	0,81	neutral	0,34	deleterious	3,35	22,9	0,06	0,35	disease	0,82	disease	0,84	disease	0,84	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,89	low_impact	-3,54	medium_impact	0,25	medium_impact	1,35	0,51	0,8	NA	NA	P	0,57	P	0,97	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4986	4986	A	T	MI.13846	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	517	173	T	S	Acc/Tcc	3,02	1	0	probably_damaging	1	neutral	0,45	neutral	4,54	neutral	-1,66	deleterious	-3,91	medium_impact	2,25	neutral	0,92	damaging	0,15	deleterious	3,19	22,7	0,36	0,5	neutral	0,46	disease	0,67	neutral	0,48	neutral	0,4	2	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,16	medium_impact	0,75	0,48	0,8	0,29	10,09	N	0,51	P	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4986	4986	A	C	MI.13847	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	517	173	T	P	Acc/Ccc	3,02	1	0	probably_damaging	1	neutral	0,2	neutral	4,4	deleterious	-3,85	deleterious	-5,87	medium_impact	2,81	neutral	0,86	damaging	0,24	deleterious	3,42	23	0,04	0,35	disease	0,76	disease	0,77	disease	0,63	neutral	0,37	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,13	medium_impact	1,22	0,25	0,8	0,29	10,09	N	0,46	N	0,97	polymorphism	1	0,09	.	.	.	.	.	oral cancer	.	.	.	.	.	.	.	.	.
chrM	4986	4986	A	G	MI.13848	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	517	173	T	A	Acc/Gcc	3,02	1	0	probably_damaging	1	neutral	0,52	neutral	4,46	neutral	-2,29	deleterious	-4,89	high_impact	3,62	neutral	0,88	damaging	0,14	deleterious	3,39	23	0,14	0,4	neutral	0,48	disease	0,65	disease	0,6	disease	0,64	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,23	medium_impact	1,9	0,35	0,8	0,29	10,09	N	0,47	N	0,69	polymorphism	1	0,09	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	4987	4987	C	A	MI.13849	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	518	173	T	N	aCc/aAc	6,71	1	0	probably_damaging	1	neutral	0,31	neutral	4,49	neutral	-1,27	deleterious	-4,89	medium_impact	2,61	neutral	0,9	damaging	0,14	deleterious	3,82	23,4	0,29	0,45	neutral	0,3	disease	0,83	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,02	medium_impact	1,05	0,55	0,8	0,29	10,09	P	0,58	P	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9176	9176	T	G	MI.1385	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	650	217	L	R	cTa/cGa	-0,1	0	0,01	probably_damaging	1	deleterious	0	neutral	2,16	deleterious	-9,28	deleterious	-5,36	high_impact	4,57	damaging	0,18	neutral	0,36	deleterious	4,29	24	0,11	0,65	NA	NA	disease	0,88	disease	0,85	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,6	low_impact	-1,4	high_impact	2,82	0,37	0,9	50	9,01	P	0,9	P	0,99	disease_causing_automatic	0,9	0,41	rs199476135	Pathogenic|Pathogenic,Pathogenic	Striatonigral_degeneration,_infantile,_mitochondrial|Leigh_syndrome,Leigh_syndrome	RCV000010278.4|RCV000010279.5,RCV000010285.5	MedGen:OMIM|MedGen:OMIM:Orphanet:SNOMED_CT,MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	T9176G	Leigh Disease/Spastic Paraplegia	-	+	Cfrm	3
chrM	4987	4987	C	G	MI.13850	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	518	173	T	S	aCc/aGc	6,71	1	0	probably_damaging	1	neutral	0,45	neutral	4,54	neutral	-1,66	deleterious	-3,91	medium_impact	2,25	neutral	0,92	damaging	0,15	deleterious	3,54	23,1	0,36	0,5	neutral	0,46	disease	0,67	neutral	0,48	neutral	0,4	2	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,16	medium_impact	0,75	0,48	0,8	0,29	10,09	P	0,58	P	0,89	polymorphism	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4987	4987	C	T	MI.13851	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	518	173	T	I	aCc/aTc	6,71	1	0	probably_damaging	1	neutral	0,44	neutral	4,53	deleterious	-3,46	deleterious	-5,87	medium_impact	2,77	neutral	0,88	damaging	0,13	deleterious	3,94	23,5	0,12	0,4	neutral	0,22	disease	0,83	disease	0,51	disease	0,66	3	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,15	medium_impact	1,19	0,45	0,8	0,29	10,09	N	0,5	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4989	4989	C	A	MI.13852	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	520	174	Q	K	Cag/Aag	-10,56	0	0	probably_damaging	0,99	neutral	0,29	neutral	4,73	neutral	0,6	deleterious	-3,91	medium_impact	3,27	neutral	0,83	damaging	0,11	deleterious	4,02	23,6	0,22	0,45	disease	0,58	disease	0,85	disease	0,69	disease	0,68	4	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,85	low_impact	-2,62	medium_impact	-0,01	medium_impact	1,61	0,42	0,8	0,58	6,75	N	0,28	N	0,8	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4989	4989	C	G	MI.13853	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	520	174	Q	E	Cag/Gag	-10,56	0	0	probably_damaging	0,99	neutral	0,27	neutral	4,62	neutral	0,81	deleterious	-2,93	medium_impact	3,12	neutral	0,85	damaging	0,12	deleterious	3,11	22,5	0,3	0,45	disease	0,61	disease	0,77	disease	0,67	disease	0,66	3	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,84	low_impact	-2,62	medium_impact	-0,03	medium_impact	1,48	0,33	0,8	0,58	6,75	N	0,28	N	0,74	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4990	4990	A	T	MI.13854	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	521	174	Q	L	cAg/cTg	5,55	1	0	probably_damaging	1	neutral	0,68	neutral	4,55	neutral	-1,38	deleterious	-6,84	medium_impact	2,38	neutral	0,91	damaging	0,13	deleterious	3,9	23,5	0,05	0,35	neutral	0,29	disease	0,88	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,39	medium_impact	0,86	0,35	0,8	0,58	6,75	N	0,49	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4990	4990	A	G	MI.13855	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	521	174	Q	R	cAg/cGg	5,55	1	0	probably_damaging	0,99	neutral	0,35	neutral	4,58	neutral	0,46	deleterious	-3,91	medium_impact	3,12	neutral	0,83	damaging	0,12	deleterious	3,55	23,1	0,21	0,45	disease	0,62	disease	0,84	disease	0,71	disease	0,69	4	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,85	low_impact	-2,62	medium_impact	0,06	medium_impact	1,48	0,29	0,8	0,58	6,75	P	0,57	P	0,64	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4990	4990	A	C	MI.13856	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	521	174	Q	P	cAg/cCg	5,55	1	0	probably_damaging	1	neutral	0,2	neutral	4,54	neutral	-1,81	deleterious	-5,87	medium_impact	3,48	neutral	0,77	damaging	0,11	deleterious	3,45	23	0,03	0,35	disease	0,73	disease	0,89	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,89	low_impact	-3,54	medium_impact	-0,13	medium_impact	1,79	0,33	0,8	0,58	6,75	P	0,6	P	0,92	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4991	4991	G	T	MI.13857	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	522	174	Q	H	caG/caT	6,71	1	0,02	probably_damaging	1	neutral	0,54	neutral	4,55	neutral	-1,05	deleterious	-4,89	medium_impact	2,23	neutral	0,92	neutral	0,66	deleterious	2,41	18,87	0,25	0,45	disease	0,72	disease	0,74	neutral	0,49	neutral	0,2	6	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0,25	medium_impact	0,73	0,61	0,8	0,58	6,75	P	0,56	P	0,51	polymorphism	1	0,07	rs386828958	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4991	4991	G	C	MI.13858	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	522	174	Q	H	caG/caC	6,71	1	0,02	probably_damaging	1	neutral	0,54	neutral	4,55	neutral	-1,05	deleterious	-4,89	medium_impact	2,23	neutral	0,92	neutral	0,66	deleterious	2,29	18,11	0,25	0,45	disease	0,72	disease	0,74	neutral	0,49	neutral	0,2	6	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0,25	medium_impact	0,73	0,61	0,8	0,58	6,75	P	0,56	P	0,51	polymorphism	1	0,07	rs386828958	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4992	4992	C	A	MI.13859	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	523	175	L	M	Cta/Ata	1,64	0,79	0	probably_damaging	1	neutral	0,43	neutral	4,45	neutral	-1,75	neutral	-1,94	low_impact	1,74	neutral	0,89	neutral	0,79	deleterious	2,86	21,7	0,28	0,45	neutral	0,43	neutral	0,37	neutral	0,3	neutral	0,47	1	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	0,14	medium_impact	0,32	0,65	0,8	1,44	7,27	N	0,4	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9178	9178	G	A	MI.1386	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	652	218	V	M	Gta/Ata	-1,26	0	0	probably_damaging	1	neutral	0,05	neutral	4,31	neutral	-1,11	neutral	-1,45	low_impact	0,96	neutral	0,82	neutral	0,51	deleterious	3,8	23,4	0,43	0,65	NA	NA	neutral	0,39	neutral	0,36	neutral	0,17	7	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,72	low_impact	-3,6	medium_impact	-0,43	medium_impact	-0,28	0,94	0,95	20,35	9,08	N	0,38	N	0,82	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4992	4992	C	G	MI.13860	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	523	175	L	V	Cta/Gta	1,64	0,79	0	probably_damaging	1	neutral	0,53	neutral	4,5	neutral	-0,58	deleterious	-2,91	medium_impact	2,02	neutral	0,91	damaging	0,26	deleterious	3,39	23	0,24	0,45	neutral	0,5	neutral	0,47	neutral	0,47	neutral	0,34	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0,24	medium_impact	0,56	0,48	0,8	1,44	7,27	N	0,3	N	0,44	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4993	4993	T	C	MI.13861	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	524	175	L	P	cTa/cCa	-0,66	0	0	probably_damaging	1	neutral	0,19	neutral	4,34	deleterious	-4,82	deleterious	-6,82	high_impact	3,81	neutral	0,83	damaging	0,1	deleterious	3,93	23,5	0,03	0,35	disease	0,8	disease	0,88	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	-0,14	high_impact	2,06	0,22	0,8	1,44	7,27	N	0,31	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4993	4993	T	G	MI.13862	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	524	175	L	R	cTa/cGa	-0,66	0	0	probably_damaging	1	neutral	0,48	neutral	4,35	deleterious	-4,75	deleterious	-5,84	high_impact	3,81	neutral	0,82	damaging	0,1	deleterious	4,22	23,9	0,03	0,35	disease	0,68	disease	0,84	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,19	high_impact	2,06	0,12	0,8	1,44	7,27	N	0,28	N	0,97	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4993	4993	T	A	MI.13863	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	524	175	L	Q	cTa/cAa	-0,66	0	0	probably_damaging	1	neutral	0,26	neutral	4,34	deleterious	-4,88	deleterious	-5,84	high_impact	3,81	neutral	0,87	damaging	0,13	deleterious	4,1	23,7	0,04	0,35	disease	0,67	disease	0,75	disease	0,6	disease	0,64	3	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	-0,04	high_impact	2,06	0,2	0,8	1,44	7,27	N	0,34	N	0,94	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4995	4995	C	A	MI.13864	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	526	176	R	S	Cgc/Agc	-1,58	0	0	possibly_damaging	0,76	neutral	0,46	neutral	4,38	deleterious	-3,93	deleterious	-5,78	medium_impact	3,25	neutral	0,73	neutral	0,44	deleterious	2,93	22	0,03	0,35	disease	0,57	disease	0,9	disease	0,66	disease	0,7	4	neutral	0,75	neutral	0,35	NA	0	deleterious	0,82	low_impact	-1,26	medium_impact	0,17	medium_impact	1,59	0,11	0,8	NA	NA	N	0,31	N	0,81	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4995	4995	C	T	MI.13865	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	526	176	R	C	Cgc/Tgc	-1,58	0	0	probably_damaging	0,97	neutral	0,17	neutral	4,36	deleterious	-6,79	deleterious	-7,7	high_impact	4,05	neutral	0,87	damaging	0,25	deleterious	4,95	25	0,05	0,35	disease	0,85	disease	0,92	disease	0,7	disease	0,64	3	deleterious	0,98	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-2,18	medium_impact	-0,17	high_impact	2,27	0,63	0,8	NA	NA	N	0,42	N	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4995	4995	C	G	MI.13866	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	526	176	R	G	Cgc/Ggc	-1,58	0	0	possibly_damaging	0,81	neutral	0,33	neutral	4,37	deleterious	-4,62	deleterious	-6,74	high_impact	4,05	neutral	0,76	neutral	0,42	deleterious	2,56	19,85	0,03	0,35	disease	0,56	disease	0,84	disease	0,7	disease	0,7	4	neutral	0,84	neutral	0,26	deleterious	1	deleterious	0,78	low_impact	-1,37	medium_impact	0,04	high_impact	2,27	0,12	0,8	NA	NA	N	0,37	N	0,95	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4996	4996	G	T	MI.13867	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	527	176	R	L	cGc/cTc	3,48	0,99	0	possibly_damaging	0,81	neutral	0,7	neutral	4,38	deleterious	-4,16	deleterious	-6,74	medium_impact	3,37	neutral	0,7	neutral	0,32	deleterious	2,75	21,1	0,03	0,35	neutral	0,27	disease	0,94	disease	0,66	disease	0,76	5	neutral	0,77	neutral	0,45	NA	0	deleterious	0,79	low_impact	-1,37	medium_impact	0,41	medium_impact	1,69	0,04	0,8	NA	NA	N	0,46	N	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4996	4996	G	A	MI.13868	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	527	176	R	H	cGc/cAc	3,48	0,99	0	benign	0,08	neutral	0,54	neutral	4,38	deleterious	-4,13	deleterious	-4,82	high_impact	3,71	neutral	0,68	damaging	0,2	deleterious	2,54	19,7	0,13	0,4	disease	0,8	disease	0,88	disease	0,58	disease	0,65	3	neutral	0,39	deleterious	0,73	neutral	-2	deleterious	0,44	medium_impact	0,17	medium_impact	0,25	medium_impact	1,98	0,57	0,8	NA	NA	N	0,52	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4996	4996	G	C	MI.13869	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	527	176	R	P	cGc/cCc	3,48	0,99	0	probably_damaging	0,95	neutral	0,2	neutral	4,37	deleterious	-5,04	deleterious	-6,75	high_impact	3,71	neutral	0,71	neutral	0,29	deleterious	4,13	23,8	0,02	0,35	disease	0,82	disease	0,93	disease	0,77	disease	0,67	3	neutral	0,97	neutral	0,13	deleterious	2	deleterious	0,9	low_impact	-1,97	medium_impact	-0,13	medium_impact	1,98	0,07	0,8	NA	NA	P	0,58	P	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9178	9178	G	C	MI.1387	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	652	218	V	L	Gta/Cta	-1,26	0	0	probably_damaging	0,98	neutral	1	neutral	4,47	neutral	0,14	neutral	-0,8	neutral_impact	-0,9	neutral	0,7	neutral	0,58	neutral	0,91	10,13	0,38	0,65	NA	NA	neutral	0,14	neutral	0,14	neutral	0,21	6	neutral	0,98	deleterious	0,51	neutral	-2	deleterious	0,67	low_impact	-2,36	high_impact	1,98	low_impact	-1,87	0,61	0,9	20,35	9,08	N	0,31	N	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4998	4998	A	G	MI.13870	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	529	177	K	E	Aaa/Gaa	0,49	0,98	0	probably_damaging	1	neutral	0,27	neutral	4,39	neutral	-1,62	deleterious	-3,84	high_impact	3,69	neutral	0,78	damaging	0,09	deleterious	4,05	23,7	0,13	0,4	neutral	0,41	disease	0,89	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,03	medium_impact	1,96	0,43	0,8	NA	NA	N	0,46	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4998	4998	A	C	MI.13871	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	529	177	K	Q	Aaa/Caa	0,49	0,98	0	probably_damaging	1	neutral	0,29	neutral	4,35	neutral	-1,92	deleterious	-3,84	medium_impact	3,23	neutral	0,72	damaging	0,08	deleterious	3,5	23,1	0,29	0,45	neutral	0,45	disease	0,86	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,57	0,43	0,8	NA	NA	N	0,47	N	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4999	4999	A	C	MI.13872	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	530	177	K	T	aAa/aCa	8,55	1	0	probably_damaging	1	neutral	0,39	neutral	4,34	neutral	-2,45	deleterious	-5,76	medium_impact	2,88	neutral	0,74	damaging	0,09	deleterious	3,63	23,2	0,06	0,35	neutral	0,26	disease	0,87	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	0,1	medium_impact	1,28	0,22	0,8	NA	NA	N	0,51	P	0,81	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	4999	4999	A	T	MI.13873	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	530	177	K	M	aAa/aTa	8,55	1	0	probably_damaging	1	neutral	0,22	neutral	4,32	deleterious	-4,05	deleterious	-5,76	medium_impact	3,06	neutral	0,75	damaging	0,07	deleterious	3,99	23,6	0,07	0,35	disease	0,77	disease	0,87	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	-0,1	medium_impact	1,43	0,19	0,8	NA	NA	P	0,56	P	0,45	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5000	5000	A	C	MI.13874	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	531	177	K	N	aaA/aaC	8,55	1	0	probably_damaging	1	neutral	0,31	neutral	4,38	neutral	-2,42	deleterious	-4,8	high_impact	4,04	neutral	0,7	damaging	0,07	deleterious	3,85	23,4	0,27	0,45	neutral	0,24	disease	0,86	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	0,02	high_impact	2,26	0,55	0,8	NA	NA	P	0,62	P	0,69	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5000	5000	A	T	MI.13875	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	531	177	K	N	aaA/aaT	8,55	1	0	probably_damaging	1	neutral	0,31	neutral	4,38	neutral	-2,42	deleterious	-4,8	high_impact	4,04	neutral	0,7	damaging	0,07	deleterious	3,91	23,5	0,27	0,45	neutral	0,24	disease	0,86	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	0,02	high_impact	2,26	0,55	0,8	NA	NA	P	0,62	P	0,69	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5001	5001	A	T	MI.13876	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	532	178	I	F	Atc/Ttc	2,1	1	0	probably_damaging	0,97	neutral	0,45	neutral	4,46	neutral	-1,8	deleterious	-3,83	high_impact	3,88	neutral	0,86	neutral	0,46	deleterious	3,6	23,2	0,06	0,35	disease	0,68	disease	0,85	disease	0,63	disease	0,68	4	neutral	0,97	neutral	0,24	deleterious	2	deleterious	0,84	low_impact	-2,18	medium_impact	0,16	high_impact	2,12	0,54	0,8	0,86	7,97	N	0,52	P	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5001	5001	A	G	MI.13877	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	532	178	I	V	Atc/Gtc	2,1	1	0	possibly_damaging	0,8	neutral	0,32	neutral	4,67	neutral	0,05	neutral	-0,95	medium_impact	2,29	neutral	0,91	neutral	0,72	deleterious	2,88	21,8	0,36	0,5	neutral	0,5	neutral	0,46	neutral	0,44	neutral	0,31	4	neutral	0,83	neutral	0,26	NA	0	deleterious	0,65	low_impact	-1,35	medium_impact	0,03	medium_impact	0,78	0,6	0,8	0,86	7,97	P	0,56	P	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5001	5001	A	C	MI.13878	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	532	178	I	L	Atc/Ctc	2,1	1	0	possibly_damaging	0,8	neutral	0,78	neutral	4,77	neutral	1,86	neutral	-1,91	low_impact	1,28	neutral	0,85	neutral	0,55	deleterious	3,6	23,2	0,21	0,45	neutral	0,42	disease	0,7	neutral	0,39	neutral	0,17	7	neutral	0,76	deleterious	0,49	neutral	-3	deleterious	0,71	low_impact	-1,35	medium_impact	0,51	medium_impact	-0,07	0,36	0,8	0,86	7,97	N	0,38	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5002	5002	T	A	MI.13879	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	533	178	I	N	aTc/aAc	3,25	1	0	probably_damaging	0,95	neutral	0,2	neutral	4,41	deleterious	-3,84	deleterious	-6,68	high_impact	3,88	neutral	0,92	neutral	0,51	deleterious	4,63	24,5	0,06	0,35	disease	0,5	disease	0,89	disease	0,61	disease	0,68	4	neutral	0,97	neutral	0,13	deleterious	2	deleterious	0,81	low_impact	-1,97	medium_impact	-0,13	high_impact	2,12	0,14	0,8	0,86	7,97	P	0,6	P	0,97	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9178	9178	G	T	MI.1388	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	652	218	V	L	Gta/Tta	-1,26	0	0	probably_damaging	0,98	neutral	1	neutral	4,47	neutral	0,14	neutral	-0,8	neutral_impact	-0,9	neutral	0,7	neutral	0,58	neutral	1,07	11,05	0,38	0,65	NA	NA	neutral	0,14	neutral	0,14	neutral	0,21	6	neutral	0,98	deleterious	0,51	neutral	-2	deleterious	0,67	low_impact	-2,36	high_impact	1,98	low_impact	-1,87	0,61	0,9	20,35	9,08	N	0,31	N	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5002	5002	T	G	MI.13880	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	533	178	I	S	aTc/aGc	3,25	1	0	benign	0,34	neutral	0,64	neutral	4,46	neutral	-2,55	deleterious	-5,72	high_impact	3,88	neutral	0,88	neutral	0,58	deleterious	4,29	24	0,03	0,35	disease	0,57	disease	0,89	disease	0,61	disease	0,68	4	neutral	0,29	deleterious	0,65	neutral	-2	deleterious	0,53	medium_impact	-0,53	medium_impact	0,35	high_impact	2,12	0,12	0,8	0,86	7,97	N	0,5	N	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5002	5002	T	C	MI.13881	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	533	178	I	T	aTc/aCc	3,25	1	0	possibly_damaging	0,77	neutral	0,2	neutral	4,45	neutral	-2,07	deleterious	-4,76	medium_impact	2,99	neutral	0,94	neutral	0,49	deleterious	3,44	23	0,05	0,35	disease	0,5	disease	0,83	disease	0,61	disease	0,65	3	neutral	0,87	neutral	0,22	NA	0	deleterious	0,75	low_impact	-1,28	medium_impact	-0,13	medium_impact	1,37	0,23	0,8	0,86	7,97	P	0,58	P	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5003	5003	C	G	MI.13882	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	534	178	I	M	atC/atG	5,78	1	0	probably_damaging	0,98	neutral	0,32	neutral	4,45	neutral	0,86	deleterious	-2,87	medium_impact	2,02	neutral	0,91	neutral	0,69	deleterious	3,36	22,9	0,16	0,45	disease	0,68	disease	0,7	neutral	0,41	neutral	0,21	6	deleterious	0,98	neutral	0,17	deleterious	1	deleterious	0,76	low_impact	-2,34	medium_impact	0,03	medium_impact	0,56	0,57	0,8	0,86	7,97	P	0,58	P	0,45	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5003	5003	C	A	MI.13883	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	534	178	I	M	atC/atA	5,78	1	0	probably_damaging	0,98	neutral	0,32	neutral	4,45	neutral	0,86	deleterious	-2,87	medium_impact	2,02	neutral	0,91	neutral	0,69	deleterious	3,78	23,4	0,16	0,45	disease	0,68	disease	0,7	neutral	0,41	neutral	0,21	6	deleterious	0,98	neutral	0,17	deleterious	1	deleterious	0,76	low_impact	-2,34	medium_impact	0,03	medium_impact	0,56	0,57	0,8	0,86	7,97	P	0,58	P	0,45	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5004	5004	T	A	MI.13884	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	535	179	L	M	Tta/Ata	-4,11	0	0,03	possibly_damaging	0,46	neutral	0,49	neutral	4,25	deleterious	-4,14	neutral	0,81	neutral_impact	0,1	neutral	0,93	neutral	0,92	deleterious	0,85	9,74	0,15	0,4	NA	NA	neutral	0,08	neutral	0,36	neutral	0,18	6	neutral	0,48	deleterious	0,52	neutral	-3	deleterious	0,56	medium_impact	-0,73	medium_impact	0,2	low_impact	-1,06	0,48	0,8	NA	NA	N	0,41	N	0,13	polymorphism	1	0,01	rs41419549	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5004	5004	T	G	MI.13885	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	535	179	L	V	Tta/Gta	-4,11	0	0,03	possibly_damaging	0,79	neutral	0,44	neutral	4,35	deleterious	-3,68	neutral	-1,79	medium_impact	2,73	neutral	0,9	neutral	0,65	deleterious	3,42	23	0,1	0,4	NA	NA	disease	0,68	disease	0,69	disease	0,67	3	neutral	0,79	neutral	0,33	NA	0	deleterious	0,75	low_impact	-1,32	medium_impact	0,15	medium_impact	1,15	0,44	0,8	NA	NA	N	0,34	N	0,31	polymorphism	1	0,03	rs41419549	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5005	5005	T	C	MI.13886	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	536	179	L	S	tTa/tCa	-4,35	0	0	probably_damaging	0,95	neutral	0,68	neutral	4,13	deleterious	-7,07	deleterious	-4,13	medium_impact	2,98	neutral	0,81	neutral	0,56	deleterious	3,74	23,3	0,02	0,35	NA	NA	disease	0,81	disease	0,7	disease	0,69	4	neutral	0,95	neutral	0,37	deleterious	1	deleterious	0,84	low_impact	-1,97	medium_impact	0,39	medium_impact	1,36	0,28	0,8	NA	NA	N	0,25	N	0,78	polymorphism	1	0,29	rs879008075	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5005	5005	T	G	MI.13887	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	536	179	L	W	tTa/tGa	-4,35	0	0	probably_damaging	0,99	neutral	0,17	neutral	4,11	deleterious	-7,9	deleterious	-4,13	high_impact	3,53	neutral	0,84	neutral	0,42	deleterious	3,74	23,3	0,02	0,35	NA	NA	disease	0,84	disease	0,72	disease	0,72	4	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-2,62	medium_impact	-0,17	medium_impact	1,83	0,21	0,8	NA	NA	N	0,4	N	0,84	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5006	5006	A	T	MI.13888	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	537	179	L	F	ttA/ttT	7,4	1	0	probably_damaging	0,95	neutral	0,62	neutral	4,14	deleterious	-4,38	deleterious	-2,75	medium_impact	2,43	neutral	0,84	neutral	0,52	deleterious	3,59	23,2	0,06	0,35	NA	NA	disease	0,77	disease	0,69	disease	0,68	4	neutral	0,95	neutral	0,34	deleterious	1	deleterious	0,82	low_impact	-1,97	medium_impact	0,33	medium_impact	0,9	0,37	0,8	NA	NA	N	0,51	P	0,45	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5006	5006	A	C	MI.13889	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	537	179	L	F	ttA/ttC	7,4	1	0	probably_damaging	0,95	neutral	0,62	neutral	4,14	deleterious	-4,38	deleterious	-2,75	medium_impact	2,43	neutral	0,84	neutral	0,52	deleterious	3,48	23,1	0,06	0,35	NA	NA	disease	0,77	disease	0,69	disease	0,68	4	neutral	0,95	neutral	0,34	deleterious	1	deleterious	0,82	low_impact	-1,97	medium_impact	0,33	medium_impact	0,9	0,37	0,8	NA	NA	N	0,5	N	0,45	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9179	9179	T	A	MI.1389	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	653	218	V	E	gTa/gAa	0,36	0,15	0	probably_damaging	1	deleterious	0,01	neutral	4,27	neutral	-1,46	deleterious	-4,78	medium_impact	2,86	neutral	0,77	neutral	0,43	deleterious	4,85	24,8	0,18	0,65	NA	NA	disease	0,8	disease	0,64	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,35	0,41	0,9	20,35	9,08	N	0,33	N	1	polymorphism	0,98	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5007	5007	G	T	MI.13890	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	538	180	A	S	Gca/Tca	0,49	0,99	0	possibly_damaging	0,79	neutral	0,44	neutral	2,93	deleterious	-5,79	deleterious	-2,88	medium_impact	2,86	neutral	0,85	neutral	0,57	deleterious	3,71	23,3	0,05	0,35	neutral	0,28	disease	0,83	disease	0,67	disease	0,69	4	neutral	0,79	neutral	0,33	NA	0	deleterious	0,75	low_impact	-1,32	medium_impact	0,15	medium_impact	1,26	0,55	0,8	NA	NA	N	0,45	N	0,57	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5007	5007	G	A	MI.13891	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	538	180	A	T	Gca/Aca	0,49	0,99	0	probably_damaging	0,95	neutral	0,38	neutral	2,92	deleterious	-7,84	deleterious	-3,87	medium_impact	2,27	neutral	0,82	neutral	0,4	deleterious	4,23	23,9	0,03	0,35	disease	0,63	disease	0,86	disease	0,69	disease	0,71	4	neutral	0,95	neutral	0,22	deleterious	1	deleterious	0,83	low_impact	-1,97	medium_impact	0,09	medium_impact	0,77	0,72	0,85	NA	NA	N	0,42	N	0,75	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5007	5007	G	C	MI.13892	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	538	180	A	P	Gca/Cca	0,49	0,99	0	probably_damaging	0,98	neutral	0,2	neutral	2,89	deleterious	-9,43	deleterious	-4,83	high_impact	4,05	neutral	0,76	neutral	0,41	deleterious	3,83	23,4	0,02	0,35	disease	0,79	disease	0,89	disease	0,8	disease	0,73	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-2,34	medium_impact	-0,13	high_impact	2,27	0,51	0,8	NA	NA	P	0,54	P	0,94	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5008	5008	C	A	MI.13893	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	539	180	A	E	gCa/gAa	9,01	1	0	probably_damaging	0,97	neutral	0,26	neutral	2,89	deleterious	-10,66	deleterious	-4,83	high_impact	4,05	neutral	0,85	neutral	0,4	deleterious	4,57	24,4	0,02	0,35	neutral	0,41	disease	0,9	disease	0,77	disease	0,72	4	neutral	0,97	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-2,18	medium_impact	-0,04	high_impact	2,27	0,4	0,8	NA	NA	P	0,63	P	0,92	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5008	5008	C	T	MI.13894	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	539	180	A	V	gCa/gTa	9,01	1	0	probably_damaging	0,95	neutral	0,5	neutral	2,95	deleterious	-8,81	deleterious	-3,88	medium_impact	2,81	neutral	0,81	neutral	0,41	deleterious	4,41	24,1	0,03	0,35	disease	0,75	disease	0,85	disease	0,69	disease	0,71	4	neutral	0,94	neutral	0,28	deleterious	1	deleterious	0,83	low_impact	-1,97	medium_impact	0,21	medium_impact	1,22	0,69	0,85	NA	NA	N	0,54	P	0,8	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5008	5008	C	G	MI.13895	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	539	180	A	G	gCa/gGa	9,01	1	0	benign	0,1	neutral	0,33	neutral	2,99	deleterious	-6,08	deleterious	-3,79	medium_impact	2,31	neutral	0,83	neutral	0,67	deleterious	3,87	23,5	0,04	0,35	disease	0,68	disease	0,77	disease	0,64	disease	0,57	1	neutral	0,62	deleterious	0,62	neutral	-3	neutral	0,32	medium_impact	0,08	medium_impact	0,04	medium_impact	0,8	0,71	0,85	NA	NA	P	0,58	P	0,39	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5010	5010	T	A	MI.13896	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	541	181	Y	N	Tac/Aac	-6,65	0	0	probably_damaging	1	neutral	0,31	neutral	4,14	deleterious	-9,03	deleterious	-8,49	medium_impact	3,41	neutral	0,86	damaging	0,12	deleterious	4,04	23,7	0,03	0,35	neutral	0,44	disease	0,88	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,02	medium_impact	1,73	0,11	0,8	NA	NA	N	0,37	N	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5010	5010	T	C	MI.13897	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	541	181	Y	H	Tac/Cac	-6,65	0	0	probably_damaging	1	neutral	0,54	neutral	4,14	deleterious	-7,6	deleterious	-4,74	high_impact	3,76	neutral	0,84	damaging	0,09	deleterious	3,58	23,2	0,04	0,35	disease	0,62	disease	0,82	disease	0,8	disease	0,75	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,25	high_impact	2,02	0,2	0,8	NA	NA	N	0,33	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5010	5010	T	G	MI.13898	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	541	181	Y	D	Tac/Gac	-6,65	0	0	probably_damaging	1	neutral	0,2	neutral	4,14	deleterious	-11,05	deleterious	-9,41	high_impact	3,76	neutral	0,85	damaging	0,08	deleterious	4	23,6	0,02	0,35	neutral	0,37	disease	0,92	disease	0,79	disease	0,75	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,13	high_impact	2,02	0,13	0,8	NA	NA	N	0,45	N	0,96	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5011	5011	A	G	MI.13899	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	542	181	Y	C	tAc/tGc	5,55	1	0	probably_damaging	1	neutral	0,18	neutral	4,17	deleterious	-10,89	deleterious	-8,46	medium_impact	2,79	neutral	0,78	damaging	0,09	deleterious	3,37	22,9	0,03	0,35	disease	0,58	disease	0,9	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,16	medium_impact	1,2	0,13	0,8	NA	NA	N	0,46	N	1	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8591	8591	T	A	MI.139	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	65	22	L	Q	cTg/cAg	-5,89	0	0	possibly_damaging	0,8	deleterious	0,01	neutral	4,11	deleterious	-3,74	deleterious	-4,23	medium_impact	3,12	neutral	0,8	neutral	0,45	deleterious	3,87	23,5	0,18	0,65	disease	0,85	disease	0,65	disease	0,58	disease	0,71	4	deleterious	0,99	neutral	0,11	deleterious	4	deleterious	0,71	low_impact	-1,33	medium_impact	-0,84	medium_impact	1,58	0,61	0,9	25,22	20,33	N	0,33	N	0,52	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9179	9179	T	C	MI.1390	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	653	218	V	A	gTa/gCa	0,36	0,15	0	probably_damaging	0,99	neutral	0,11	neutral	4,35	neutral	0,68	deleterious	-2,98	low_impact	1,48	neutral	0,76	neutral	0,58	deleterious	3,7	23,3	0,33	0,65	NA	NA	neutral	0,34	neutral	0,49	neutral	0,17	7	deleterious	0,99	neutral	0,06	neutral	-2	deleterious	0,73	low_impact	-2,65	medium_impact	-0,22	medium_impact	0,17	0,52	0,9	20,35	9,08	N	0,4	N	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5011	5011	A	C	MI.13900	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	542	181	Y	S	tAc/tCc	5,55	1	0	probably_damaging	1	neutral	0,41	neutral	4,17	deleterious	-9,06	deleterious	-8,45	medium_impact	3,06	neutral	0,86	damaging	0,13	deleterious	3,57	23,2	0,03	0,35	neutral	0,42	disease	0,86	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,12	medium_impact	1,43	0,15	0,8	NA	NA	N	0,47	N	0,96	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5011	5011	A	T	MI.13901	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	542	181	Y	F	tAc/tTc	5,55	1	0	probably_damaging	1	neutral	0,7	neutral	4,27	deleterious	-4,26	deleterious	-3,58	low_impact	0,89	neutral	0,89	neutral	0,65	deleterious	2,08	16,71	0,11	0,4	neutral	0,43	neutral	0,23	disease	0,54	neutral	0,43	1	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	0,41	medium_impact	-0,4	0,35	0,8	NA	NA	P	0,58	P	0,8	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5013	5013	T	A	MI.13902	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	544	182	S	T	Tcc/Acc	-0,2	0,76	0	benign	0,22	neutral	0,39	neutral	2,47	deleterious	-7,09	deleterious	-2,85	high_impact	4,12	neutral	0,76	damaging	0,09	deleterious	3,97	23,6	0,05	0,35	neutral	0,4	disease	0,75	disease	0,77	disease	0,7	4	neutral	0,53	deleterious	0,59	neutral	-2	deleterious	0,47	medium_impact	-0,29	medium_impact	0,1	high_impact	2,32	0,4	0,8	NA	NA	N	0,43	N	0,71	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5013	5013	T	G	MI.13903	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	544	182	S	A	Tcc/Gcc	-0,2	0,76	0	possibly_damaging	0,67	neutral	0,51	neutral	2,51	deleterious	-6,22	deleterious	-2,86	high_impact	4,12	neutral	0,67	damaging	0,13	deleterious	3,68	23,3	0,05	0,35	disease	0,56	disease	0,67	disease	0,75	disease	0,71	4	neutral	0,64	neutral	0,42	deleterious	1	deleterious	0,73	low_impact	-1,08	medium_impact	0,22	high_impact	2,32	0,41	0,8	NA	NA	N	0,41	N	0,49	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5013	5013	T	C	MI.13904	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	544	182	S	P	Tcc/Ccc	-0,2	0,76	0	probably_damaging	0,97	neutral	0,2	neutral	2,45	deleterious	-8,54	deleterious	-4,77	high_impact	3,78	neutral	0,73	damaging	0,05	deleterious	4,03	23,6	0,02	0,35	disease	0,67	disease	0,86	disease	0,85	disease	0,74	5	deleterious	0,98	neutral	0,12	deleterious	2	deleterious	0,86	low_impact	-2,18	medium_impact	-0,13	high_impact	2,04	0,34	0,8	NA	NA	N	0,45	N	0,99	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5014	5014	C	T	MI.13905	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	545	182	S	F	tCc/tTc	7,4	1	0	probably_damaging	0,98	neutral	0,71	neutral	2,44	deleterious	-9,94	deleterious	-5,72	high_impact	3,78	neutral	0,7	damaging	0,04	deleterious	4,27	24	0,02	0,35	disease	0,82	disease	0,89	disease	0,76	disease	0,71	4	neutral	0,98	neutral	0,37	deleterious	2	deleterious	0,87	low_impact	-2,34	medium_impact	0,42	high_impact	2,04	0,19	0,8	NA	NA	P	0,56	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5014	5014	C	G	MI.13906	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	545	182	S	C	tCc/tGc	7,4	1	0	probably_damaging	0,99	neutral	0,18	neutral	2,49	deleterious	-6,66	deleterious	-4,77	high_impact	4,12	neutral	0,71	damaging	0,05	deleterious	3,6	23,2	0,02	0,35	disease	0,9	disease	0,82	disease	0,75	disease	0,68	4	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-2,62	medium_impact	-0,16	high_impact	2,32	0,36	0,8	NA	NA	P	0,63	P	1	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5014	5014	C	A	MI.13907	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	545	182	S	Y	tCc/tAc	7,4	1	0	probably_damaging	0,99	neutral	1	neutral	2,44	deleterious	-10,34	deleterious	-5,72	high_impact	4,12	neutral	0,71	damaging	0,06	deleterious	4,1	23,7	0,02	0,35	disease	0,82	disease	0,89	disease	0,78	disease	0,72	4	deleterious	0,99	deleterious	0,51	deleterious	2	deleterious	0,87	low_impact	-2,62	high_impact	1,87	high_impact	2,32	0,35	0,8	NA	NA	P	0,59	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5016	5016	T	G	MI.13908	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	547	183	S	A	Tca/Gca	-3,19	0	0	probably_damaging	1	neutral	0,51	neutral	3,97	deleterious	-3,71	deleterious	-2,87	high_impact	3,57	neutral	0,91	damaging	0,2	deleterious	3,66	23,2	0,06	0,35	disease	0,51	disease	0,7	disease	0,76	disease	0,71	4	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	0,22	medium_impact	1,86	0,38	0,8	NA	NA	N	0,35	N	0,49	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5016	5016	T	C	MI.13909	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	547	183	S	P	Tca/Cca	-3,19	0	0	probably_damaging	1	neutral	0,2	neutral	3,91	deleterious	-6	deleterious	-4,78	high_impact	3,77	neutral	0,78	damaging	0,12	deleterious	3,97	23,6	0,02	0,35	disease	0,6	disease	0,87	disease	0,84	disease	0,76	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	-0,13	high_impact	2,03	0,27	0,8	NA	NA	N	0,41	N	0,99	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9179	9179	T	G	MI.1391	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	653	218	V	G	gTa/gGa	0,36	0,15	0	probably_damaging	1	deleterious	0	neutral	4,26	neutral	-2,12	deleterious	-5,67	medium_impact	2,86	neutral	0,76	neutral	0,54	deleterious	3,9	23,5	0,18	0,65	NA	NA	disease	0,62	disease	0,53	disease	0,63	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,6	low_impact	-1,4	medium_impact	1,35	0,41	0,9	20,35	9,08	N	0,37	N	0,95	disease_causing	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5016	5016	T	A	MI.13910	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	547	183	S	T	Tca/Aca	-3,19	0	0	probably_damaging	1	neutral	0,39	neutral	4,51	neutral	-0,37	deleterious	-2,87	high_impact	3,77	neutral	0,82	damaging	0,12	deleterious	3,79	23,4	0,06	0,35	disease	0,56	disease	0,77	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0,1	high_impact	2,03	0,54	0,8	NA	NA	N	0,29	N	0,71	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5017	5017	C	T	MI.13911	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	548	183	S	L	tCa/tTa	7,4	1	0	probably_damaging	1	neutral	0,67	neutral	3,91	deleterious	-6,25	deleterious	-5,73	high_impact	3,77	neutral	0,76	damaging	0,1	deleterious	4,61	24,4	0,02	0,35	neutral	0,23	disease	0,9	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,38	high_impact	2,03	0,44	0,8	NA	NA	N	0,52	P	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5017	5017	C	G	MI.13912	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	548	183	S	W	tCa/tGa	7,4	1	0	probably_damaging	1	neutral	0,19	neutral	3,9	deleterious	-9,39	deleterious	-6,68	high_impact	4,12	neutral	0,85	damaging	0,11	deleterious	4,33	24	0,02	0,35	disease	0,89	disease	0,93	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	-0,14	high_impact	2,32	0,12	0,8	NA	NA	P	0,63	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5019	5019	A	C	MI.13913	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	550	184	I	L	Att/Ctt	-2,27	0	0	probably_damaging	0,99	neutral	0,71	neutral	4,27	deleterious	-3,83	neutral	-1,91	medium_impact	2,88	neutral	0,88	damaging	0,16	deleterious	3,77	23,4	0,12	0,4	neutral	0,45	disease	0,72	disease	0,7	disease	0,7	4	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,77	low_impact	-2,62	medium_impact	0,42	medium_impact	1,28	0,48	0,8	NA	NA	N	0,27	N	0,85	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5019	5019	A	G	MI.13914	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	550	184	I	V	Att/Gtt	-2,27	0	0	probably_damaging	0,99	neutral	0,39	neutral	4,34	neutral	-1,05	neutral	-0,92	medium_impact	2,52	neutral	0,94	damaging	0,19	deleterious	3,01	22,3	0,36	0,5	disease	0,51	disease	0,57	disease	0,67	disease	0,55	1	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,74	low_impact	-2,62	medium_impact	0,1	medium_impact	0,98	0,44	0,8	NA	NA	N	0,36	N	0,73	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5019	5019	A	T	MI.13915	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	550	184	I	F	Att/Ttt	-2,27	0	0	probably_damaging	1	neutral	0,65	neutral	4,07	deleterious	-6,6	deleterious	-3,82	high_impact	3,54	neutral	0,86	damaging	0,13	deleterious	3,98	23,6	0,03	0,35	disease	0,71	disease	0,83	disease	0,76	disease	0,74	5	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	0,36	medium_impact	1,84	0,47	0,8	NA	NA	N	0,28	N	0,97	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5020	5020	T	G	MI.13916	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	551	184	I	S	aTt/aGt	6,71	1	0	probably_damaging	1	neutral	0,46	neutral	4,08	deleterious	-6,56	deleterious	-5,72	high_impact	4,08	neutral	0,91	damaging	0,18	deleterious	4,24	23,9	0,01	0,35	disease	0,63	disease	0,87	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,17	high_impact	2,29	0,16	0,8	NA	NA	P	0,62	P	0,95	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5020	5020	T	C	MI.13917	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	551	184	I	T	aTt/aCt	6,71	1	0	probably_damaging	1	neutral	0,31	neutral	4,08	deleterious	-5,93	deleterious	-4,75	medium_impact	3,04	neutral	0,87	damaging	0,2	deleterious	3,43	23	0,03	0,35	neutral	0,35	disease	0,77	disease	0,68	disease	0,6	2	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,02	medium_impact	1,42	0,17	0,8	NA	NA	N	0,55	P	0,96	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5020	5020	T	A	MI.13918	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	551	184	I	N	aTt/aAt	6,71	1	0	probably_damaging	1	neutral	0,21	neutral	4,05	deleterious	-8,21	deleterious	-6,68	high_impact	3,73	neutral	0,9	damaging	0,14	deleterious	4,5	24,3	0,03	0,35	disease	0,82	disease	0,85	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,11	medium_impact	2	0,24	0,8	NA	NA	P	0,63	P	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5021	5021	T	A	MI.13919	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	552	184	I	M	atT/atA	4,63	1	0,01	probably_damaging	1	neutral	0,29	neutral	4,14	deleterious	-5,01	deleterious	-2,85	medium_impact	2,98	neutral	0,95	damaging	0,17	deleterious	3,72	23,3	0,05	0,35	disease	0,56	disease	0,74	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,36	0,48	0,8	NA	NA	P	0,58	P	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9181	9181	A	T	MI.1392	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	655	219	S	C	Agc/Tgc	-2,88	0	0,01	probably_damaging	1	neutral	0,07	neutral	4,36	neutral	-0,89	deleterious	-4,4	low_impact	1,62	neutral	0,8	neutral	0,42	deleterious	3,52	23,1	0,33	0,65	NA	NA	disease	0,75	disease	0,67	disease	0,64	3	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	-0,34	medium_impact	0,29	0,8	0,9	48,23	7,68	N	0,28	N	0,99	polymorphism	0,62	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5021	5021	T	G	MI.13920	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	552	184	I	M	atT/atG	4,63	1	0,01	probably_damaging	1	neutral	0,29	neutral	4,14	deleterious	-5,01	deleterious	-2,85	medium_impact	2,98	neutral	0,95	damaging	0,17	deleterious	3,42	23	0,05	0,35	disease	0,56	disease	0,74	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,36	0,48	0,8	NA	NA	P	0,58	P	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5022	5022	A	C	MI.13921	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	553	185	T	P	Acc/Ccc	-2,04	0	0	probably_damaging	1	neutral	0,2	neutral	4,56	neutral	-2,03	neutral	-1,76	low_impact	1,32	neutral	0,7	damaging	0,21	deleterious	3,45	23	0,04	0,35	neutral	0,3	disease	0,92	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,78	low_impact	-3,54	medium_impact	-0,13	medium_impact	-0,03	0,4	0,8	2,02	8,22	N	0,28	N	0,78	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5022	5022	A	T	MI.13922	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	553	185	T	S	Acc/Tcc	-2,04	0	0	probably_damaging	1	neutral	0,41	neutral	4,89	neutral	3,13	neutral	0,16	neutral_impact	-0,84	neutral	0,85	neutral	0,91	deleterious	2,09	16,77	0,23	0,45	neutral	0,36	neutral	0,28	neutral	0,45	neutral	0,44	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,12	low_impact	-1,85	0,58	0,8	2,02	8,22	N	0,36	N	0,34	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5022	5022	A	G	MI.13923	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	553	185	T	A	Acc/Gcc	-2,04	0	0	probably_damaging	1	neutral	0,54	neutral	4,7	neutral	2,26	neutral	2,37	neutral_impact	-2,02	neutral	0,93	neutral	0,92	deleterious	0,76	9,21	0,16	0,45	neutral	0,22	neutral	0,16	neutral	0,35	neutral	0,23	5	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,64	low_impact	-3,54	medium_impact	0,25	low_impact	-2,85	0,44	0,8	2,02	8,22	N	0,3	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5023	5023	C	T	MI.13924	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	554	185	T	I	aCc/aTc	0,95	0,31	0	probably_damaging	1	neutral	0,41	neutral	4,59	neutral	-1,83	neutral	-1,77	low_impact	0,98	neutral	0,83	damaging	0,27	deleterious	3,96	23,6	0,09	0,35	neutral	0,34	disease	0,87	disease	0,56	disease	0,75	5	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,77	low_impact	-3,54	medium_impact	0,12	medium_impact	-0,32	0,6	0,8	2,02	8,22	N	0,26	N	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5023	5023	C	A	MI.13925	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	554	185	T	N	aCc/aAc	0,95	0,31	0	probably_damaging	1	neutral	0,31	neutral	4,6	neutral	-0,25	neutral	-2,37	neutral_impact	-0,74	neutral	0,79	damaging	0,27	deleterious	3,64	23,2	0,24	0,45	neutral	0,3	disease	0,84	disease	0,62	disease	0,77	5	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,73	low_impact	-3,54	medium_impact	0,02	low_impact	-1,77	0,57	0,8	2,02	8,22	N	0,22	N	0,65	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5023	5023	C	G	MI.13926	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	554	185	T	S	aCc/aGc	0,95	0,31	0	probably_damaging	1	neutral	0,41	neutral	4,89	neutral	3,13	neutral	0,16	neutral_impact	-0,84	neutral	0,85	neutral	0,91	deleterious	2,32	18,3	0,23	0,45	neutral	0,36	neutral	0,28	neutral	0,45	neutral	0,44	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,12	low_impact	-1,85	0,58	0,8	2,02	8,22	N	0,36	N	0,34	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5025	5025	C	A	MI.13927	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	556	186	H	N	Cac/Aac	-3,42	0	0	probably_damaging	0,96	neutral	0,31	neutral	4,35	neutral	-2,61	deleterious	-6,68	medium_impact	2,14	neutral	0,88	damaging	0,12	deleterious	3,91	23,5	0,12	0,4	disease	0,7	disease	0,84	disease	0,75	disease	0,6	2	neutral	0,96	neutral	0,18	deleterious	1	deleterious	0,82	low_impact	-2,06	medium_impact	0,02	medium_impact	0,66	0,38	0,8	NA	NA	N	0,31	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5025	5025	C	G	MI.13928	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	556	186	H	D	Cac/Gac	-3,42	0	0	probably_damaging	0,96	neutral	0,2	neutral	4,25	deleterious	-4,05	deleterious	-8,59	high_impact	4,07	neutral	0,9	damaging	0,11	deleterious	3,86	23,5	0,04	0,35	disease	0,75	disease	0,89	disease	0,82	disease	0,73	5	neutral	0,97	neutral	0,12	deleterious	2	deleterious	0,84	low_impact	-2,06	medium_impact	-0,13	high_impact	2,28	0,28	0,8	NA	NA	N	0,53	P	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5025	5025	C	T	MI.13929	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	556	186	H	Y	Cac/Tac	-3,42	0	0	benign	0,14	neutral	1	neutral	4,19	deleterious	-6,1	deleterious	-5,71	high_impact	4,07	neutral	0,91	damaging	0,11	deleterious	3,75	23,3	0,05	0,35	disease	0,71	disease	0,89	disease	0,77	disease	0,71	4	neutral	0,14	deleterious	0,93	neutral	-2	neutral	0,4	medium_impact	-0,08	high_impact	1,87	high_impact	2,28	0,27	0,8	NA	NA	N	0,27	N	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9181	9181	A	C	MI.1393	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	655	219	S	R	Agc/Cgc	-2,88	0	0,01	probably_damaging	0,99	deleterious	0,02	neutral	4,29	neutral	-2,94	deleterious	-4,28	high_impact	3,8	neutral	0,82	neutral	0,4	deleterious	3,94	23,5	0,17	0,65	NA	NA	disease	0,84	disease	0,79	disease	0,8	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-2,65	medium_impact	-0,66	high_impact	2,16	0,77	0,9	48,23	7,68	N	0,43	N	1	polymorphism	0,57	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5026	5026	A	G	MI.13930	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	557	186	H	R	cAc/cGc	5,55	1	0	probably_damaging	0,94	neutral	0,35	neutral	4,23	deleterious	-4,17	deleterious	-7,63	high_impact	4,07	neutral	0,93	damaging	0,12	deleterious	3	22,2	0,04	0,35	disease	0,68	disease	0,91	disease	0,8	disease	0,73	5	neutral	0,94	neutral	0,21	deleterious	2	deleterious	0,88	low_impact	-1,89	medium_impact	0,06	high_impact	2,28	0,43	0,8	NA	NA	P	0,7	P	0,98	polymorphism	1	0,35	.	.	.	.	.	oral cancer	.	.	.	.	.	.	.	.	.
chrM	5026	5026	A	C	MI.13931	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	557	186	H	P	cAc/cCc	5,55	1	0	probably_damaging	0,98	neutral	0,2	neutral	4,2	deleterious	-5,62	deleterious	-9,54	high_impact	3,71	neutral	0,86	damaging	0,1	deleterious	3,26	22,8	0,03	0,35	disease	0,79	disease	0,9	disease	0,84	disease	0,73	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-2,34	medium_impact	-0,13	medium_impact	1,98	0,2	0,8	NA	NA	P	0,65	P	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5026	5026	A	T	MI.13932	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	557	186	H	L	cAc/cTc	5,55	1	0	possibly_damaging	0,85	neutral	0,66	neutral	4,2	deleterious	-5,07	deleterious	-10,48	high_impact	4,07	neutral	0,93	damaging	0,1	deleterious	3,93	23,5	0,03	0,35	neutral	0,26	disease	0,92	disease	0,77	disease	0,69	4	neutral	0,82	neutral	0,41	deleterious	1	deleterious	0,75	low_impact	-1,49	medium_impact	0,37	high_impact	2,28	0,25	0,8	NA	NA	P	0,61	P	0,97	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5027	5027	C	A	MI.13933	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	558	186	H	Q	caC/caA	4,63	0,99	0	probably_damaging	0,98	neutral	0,29	neutral	4,54	neutral	-0,67	deleterious	-7,63	medium_impact	2,67	neutral	0,88	damaging	0,1	deleterious	3,94	23,5	0,06	0,35	disease	0,56	disease	0,84	disease	0,75	disease	0,71	4	deleterious	0,98	neutral	0,16	deleterious	1	deleterious	0,82	low_impact	-2,34	medium_impact	-0,01	medium_impact	1,1	0,38	0,8	NA	NA	N	0,52	P	0,94	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5027	5027	C	G	MI.13934	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	558	186	H	Q	caC/caG	4,63	0,99	0	probably_damaging	0,98	neutral	0,29	neutral	4,54	neutral	-0,67	deleterious	-7,63	medium_impact	2,67	neutral	0,88	damaging	0,1	deleterious	3,54	23,1	0,06	0,35	disease	0,56	disease	0,84	disease	0,75	disease	0,71	4	deleterious	0,98	neutral	0,16	deleterious	1	deleterious	0,82	low_impact	-2,34	medium_impact	-0,01	medium_impact	1,1	0,38	0,8	NA	NA	N	0,52	P	0,94	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5028	5028	A	C	MI.13935	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	559	187	M	L	Ata/Cta	-4,81	0	0	benign	0,02	neutral	1	neutral	4,63	neutral	-0,06	deleterious	-2,69	neutral_impact	0,5	neutral	0,85	neutral	0,56	deleterious	0,09	3,5	0,25	0,45	neutral	0,32	neutral	0,39	disease	0,51	neutral	0,45	1	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,18	medium_impact	0,75	high_impact	1,87	medium_impact	-0,72	0,31	0,8	NA	NA	N	0,23	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5028	5028	A	T	MI.13936	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	559	187	M	L	Ata/Tta	-4,81	0	0	benign	0,02	neutral	1	neutral	4,63	neutral	-0,06	deleterious	-2,69	neutral_impact	0,5	neutral	0,85	neutral	0,56	deleterious	0,19	4,58	0,25	0,45	neutral	0,32	neutral	0,39	disease	0,51	neutral	0,45	1	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,18	medium_impact	0,75	high_impact	1,87	medium_impact	-0,72	0,31	0,8	NA	NA	N	0,24	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5028	5028	A	G	MI.13937	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	559	187	M	V	Ata/Gta	-4,81	0	0	benign	0	neutral	0,55	neutral	4,43	neutral	-1,33	deleterious	-3,7	low_impact	1,79	neutral	0,95	neutral	0,54	deleterious	0,66	8,56	0,21	0,45	neutral	0,43	disease	0,88	disease	0,68	disease	0,72	4	neutral	0,44	deleterious	0,78	neutral	-6	neutral	0,27	medium_impact	1,95	medium_impact	0,26	medium_impact	0,36	0,4	0,8	NA	NA	N	0,23	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5029	5029	T	C	MI.13938	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	560	187	M	T	aTa/aCa	-0,2	0	0	benign	0,01	neutral	0,44	neutral	4,32	deleterious	-3,09	deleterious	-5,6	low_impact	1,5	neutral	0,89	neutral	0,58	neutral	1,06	10,98	0,08	0,35	disease	0,52	disease	0,87	disease	0,69	disease	0,71	4	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,31	medium_impact	1,03	medium_impact	0,15	medium_impact	0,12	0,12	0,8	NA	NA	N	0,31	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5029	5029	T	A	MI.13939	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	560	187	M	K	aTa/aAa	-0,2	0	0	benign	0,17	neutral	0,31	neutral	4,29	deleterious	-4,36	deleterious	-5,65	medium_impact	3,42	neutral	0,84	neutral	0,39	deleterious	2,1	16,84	0,03	0,35	disease	0,68	disease	0,93	disease	0,77	disease	0,75	5	neutral	0,63	deleterious	0,57	neutral	-3	deleterious	0,44	medium_impact	-0,17	medium_impact	0,02	medium_impact	1,73	0,17	0,8	NA	NA	N	0,4	N	0,98	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9181	9181	A	G	MI.1394	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	655	219	S	G	Agc/Ggc	-2,88	0	0,01	probably_damaging	0,98	neutral	0,14	neutral	4,3	neutral	-2,6	deleterious	-3,43	medium_impact	2,38	neutral	0,97	neutral	0,63	deleterious	3,68	23,3	0,35	0,65	NA	NA	disease	0,6	disease	0,72	disease	0,68	4	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,74	low_impact	-2,36	medium_impact	-0,15	medium_impact	0,94	0,7	0,9	48,23	7,68	N	0,44	N	0,92	polymorphism	0,87	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5030	5030	A	C	MI.13940	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	561	187	M	I	atA/atC	5,78	0,9	0	benign	0,03	neutral	0,56	neutral	4,5	neutral	-0,79	deleterious	-3,67	low_impact	1,62	neutral	0,85	neutral	0,55	neutral	1,53	13,48	0,2	0,45	neutral	0,31	disease	0,91	disease	0,67	disease	0,72	4	neutral	0,4	deleterious	0,77	neutral	-6	neutral	0,28	medium_impact	0,59	medium_impact	0,27	medium_impact	0,22	0,36	0,8	NA	NA	N	0,4	N	0,93	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5030	5030	A	T	MI.13941	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	561	187	M	I	atA/atT	5,78	0,9	0	benign	0,03	neutral	0,56	neutral	4,5	neutral	-0,79	deleterious	-3,67	low_impact	1,62	neutral	0,85	neutral	0,55	neutral	1,66	14,17	0,2	0,45	neutral	0,31	disease	0,91	disease	0,67	disease	0,72	4	neutral	0,4	deleterious	0,77	neutral	-6	neutral	0,28	medium_impact	0,59	medium_impact	0,27	medium_impact	0,22	0,36	0,8	NA	NA	N	0,4	N	0,93	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5031	5031	G	T	MI.13942	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	562	188	G	W	Gga/Tga	-0,43	0,19	0	probably_damaging	1	neutral	0,2	neutral	3,38	deleterious	-13,66	deleterious	-7,65	high_impact	4,05	neutral	0,79	damaging	0,08	deleterious	4,38	24,1	0,03	0,35	disease	0,99	disease	0,92	disease	0,79	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-3,54	medium_impact	-0,13	high_impact	2,27	0,08	0,8	NA	NA	N	0,4	N	0,99	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5031	5031	G	C	MI.13943	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	562	188	G	R	Gga/Cga	-0,43	0,19	0	probably_damaging	1	neutral	0,34	neutral	3,39	deleterious	-10,82	deleterious	-7,65	high_impact	3,7	neutral	0,89	damaging	0,1	deleterious	3,9	23,5	0,02	0,35	disease	0,95	disease	0,92	disease	0,82	disease	0,63	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,92	low_impact	-3,54	medium_impact	0,05	medium_impact	1,97	0,42	0,8	NA	NA	N	0,52	P	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5032	5032	G	A	MI.13944	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	563	188	G	E	gGa/gAa	6,01	1	0	probably_damaging	1	neutral	0,27	neutral	3,4	deleterious	-10,18	deleterious	-7,65	high_impact	4,05	neutral	0,8	damaging	0,09	deleterious	3,94	23,5	0,02	0,35	disease	0,71	disease	0,9	disease	0,82	disease	0,73	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	-0,03	high_impact	2,27	0,23	0,8	NA	NA	P	0,62	P	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5032	5032	G	T	MI.13945	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	563	188	G	V	gGa/gTa	6,01	1	0	probably_damaging	1	neutral	0,5	neutral	3,4	deleterious	-9,64	deleterious	-8,61	high_impact	4,05	neutral	0,65	damaging	0,09	deleterious	3,77	23,4	0,02	0,35	disease	0,96	disease	0,91	disease	0,77	disease	0,61	2	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	0,21	high_impact	2,27	0,19	0,8	NA	NA	P	0,62	P	0,97	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5032	5032	G	C	MI.13946	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	563	188	G	A	gGa/gCa	6,01	1	0	probably_damaging	1	neutral	0,51	neutral	3,48	deleterious	-7,02	deleterious	-5,74	medium_impact	2,29	neutral	0,75	damaging	0,1	deleterious	3,11	22,5	0,03	0,35	disease	0,88	disease	0,77	disease	0,74	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0,22	medium_impact	0,78	0,27	0,8	NA	NA	N	0,49	N	0,74	polymorphism	1	0,1	.	.	.	.	.	.	COSM1637127	.	.	.	.	.	.	.	.
chrM	5034	5034	T	C	MI.13947	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	565	189	W	R	Tga/Cga	-8,72	0	0	probably_damaging	1	neutral	0,3	neutral	4,51	neutral	-0,82	deleterious	-13,38	high_impact	4,12	neutral	0,91	damaging	0,13	deleterious	3,62	23,2	0,02	0,35	disease	0,89	disease	0,93	disease	0,81	disease	0,63	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,9	low_impact	-3,54	medium_impact	0	high_impact	2,32	0,14	0,8	NA	NA	P	0,56	P	0,97	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5034	5034	T	G	MI.13948	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	565	189	W	G	Tga/Gga	-8,72	0	0	probably_damaging	1	neutral	0,38	neutral	4,51	neutral	-0,66	deleterious	-12,43	high_impact	4,12	neutral	0,81	damaging	0,12	deleterious	3,93	23,5	0,03	0,35	disease	0,9	disease	0,87	disease	0,77	disease	0,63	3	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	0,09	high_impact	2,32	0,09	0,8	NA	NA	N	0,49	N	0,96	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5035	5035	G	C	MI.13949	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	566	189	W	S	tGa/tCa	7,4	1	0	probably_damaging	1	neutral	0,53	neutral	4,53	neutral	0,18	deleterious	-13,39	high_impact	4,12	neutral	0,89	damaging	0,15	deleterious	4,01	23,6	0,02	0,35	disease	0,83	disease	0,92	disease	0,76	disease	0,66	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	0,24	high_impact	2,32	0,08	0,8	NA	NA	P	0,57	P	0,94	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9182	9182	G	C	MI.1395	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	656	219	S	T	aGc/aCc	5,68	1	0,01	probably_damaging	0,98	neutral	0,85	neutral	4,36	neutral	-0,72	deleterious	-2,55	neutral_impact	0,53	neutral	0,82	neutral	0,58	deleterious	2,34	18,45	0,26	0,65	NA	NA	neutral	0,21	disease	0,55	neutral	0,32	4	neutral	0,98	neutral	0,44	neutral	-2	deleterious	0,72	low_impact	-2,36	medium_impact	0,72	medium_impact	-0,64	0,8	0,9	48,23	7,68	N	0,43	N	0,67	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5035	5035	G	T	MI.13950	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	566	189	W	L	tGa/tTa	7,4	1	0	probably_damaging	1	neutral	0,82	neutral	4,73	neutral	2,84	deleterious	-12,43	high_impact	3,57	neutral	0,75	damaging	0,1	deleterious	4,23	23,9	0,03	0,35	neutral	0,4	disease	0,87	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,41	deleterious	2	deleterious	0,76	low_impact	-3,54	medium_impact	0,57	medium_impact	1,86	0,12	0,8	NA	NA	N	0,52	P	0,97	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5036	5036	A	C	MI.13951	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	567	189	W	C	tgA/tgC	6,01	1	0	probably_damaging	1	neutral	0,17	neutral	4,51	neutral	-1,13	deleterious	-12,43	high_impact	4,12	neutral	0,87	damaging	0,12	deleterious	3,97	23,6	0,02	0,35	disease	0,91	disease	0,91	disease	0,8	disease	0,62	2	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	-0,17	high_impact	2,32	0,12	0,8	NA	NA	P	0,67	P	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5036	5036	A	T	MI.13952	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	567	189	W	C	tgA/tgT	6,01	1	0	probably_damaging	1	neutral	0,17	neutral	4,51	neutral	-1,13	deleterious	-12,43	high_impact	4,12	neutral	0,87	damaging	0,12	deleterious	4,08	23,7	0,02	0,35	disease	0,91	disease	0,91	disease	0,8	disease	0,62	2	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	-0,17	high_impact	2,32	0,12	0,8	NA	NA	P	0,68	P	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5037	5037	A	C	MI.13953	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	568	190	M	L	Ata/Cta	5,55	1	0	probably_damaging	0,96	neutral	0,89	neutral	4,69	neutral	0,09	deleterious	-2,8	low_impact	1,56	neutral	0,95	damaging	0,16	deleterious	3,25	22,8	0,2	0,45	neutral	0,32	disease	0,81	disease	0,63	disease	0,54	1	neutral	0,96	neutral	0,47	neutral	-2	deleterious	0,78	low_impact	-2,06	medium_impact	0,71	medium_impact	0,17	0,58	0,8	NA	NA	N	0,47	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5037	5037	A	T	MI.13954	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	568	190	M	L	Ata/Tta	5,55	1	0	probably_damaging	0,96	neutral	0,89	neutral	4,69	neutral	0,09	deleterious	-2,8	low_impact	1,56	neutral	0,95	damaging	0,16	deleterious	3,35	22,9	0,2	0,45	neutral	0,32	disease	0,81	disease	0,63	disease	0,54	1	neutral	0,96	neutral	0,47	neutral	-2	deleterious	0,78	low_impact	-2,06	medium_impact	0,71	medium_impact	0,17	0,58	0,8	NA	NA	N	0,49	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5037	5037	A	G	MI.13955	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	568	190	M	V	Ata/Gta	5,55	1	0	probably_damaging	0,98	neutral	0,51	neutral	4,48	neutral	0,15	deleterious	-3,72	medium_impact	2,33	neutral	0,82	damaging	0,15	deleterious	2,7	20,8	0,19	0,45	neutral	0,38	disease	0,84	disease	0,67	disease	0,54	1	deleterious	0,98	neutral	0,27	deleterious	1	deleterious	0,79	low_impact	-2,34	medium_impact	0,22	medium_impact	0,82	0,59	0,8	NA	NA	N	0,47	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5038	5038	T	C	MI.13956	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	569	190	M	T	aTa/aCa	6,71	1	0	probably_damaging	0,99	neutral	0,36	neutral	4,45	neutral	-2,98	deleterious	-5,51	low_impact	1,55	neutral	0,93	damaging	0,19	deleterious	2,93	22	0,04	0,35	neutral	0,46	disease	0,9	disease	0,68	disease	0,55	1	deleterious	0,99	neutral	0,19	neutral	-2	deleterious	0,85	low_impact	-2,62	medium_impact	0,07	medium_impact	0,16	0,3	0,8	NA	NA	N	0,52	P	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5038	5038	T	A	MI.13957	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	569	190	M	K	aTa/aAa	6,71	1	0	probably_damaging	0,99	neutral	0,28	neutral	4,39	deleterious	-4,74	deleterious	-5,63	high_impact	3,81	neutral	0,86	damaging	0,12	deleterious	4,06	23,7	0,02	0,35	neutral	0,4	disease	0,9	disease	0,79	disease	0,7	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-2,62	medium_impact	-0,02	high_impact	2,06	0,35	0,8	NA	NA	P	0,63	P	0,98	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5039	5039	A	C	MI.13958	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	570	190	M	I	atA/atC	4,4	1	0	probably_damaging	0,98	neutral	0,87	neutral	4,54	neutral	0,47	deleterious	-3,73	low_impact	1,64	neutral	0,93	neutral	0,52	deleterious	3,32	22,9	0,17	0,45	neutral	0,32	disease	0,86	disease	0,56	neutral	0,23	5	deleterious	0,98	neutral	0,45	neutral	-2	deleterious	0,81	low_impact	-2,34	medium_impact	0,67	medium_impact	0,24	0,63	0,8	NA	NA	N	0,46	N	0,93	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5039	5039	A	T	MI.13959	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	570	190	M	I	atA/atT	4,4	1	0	probably_damaging	0,98	neutral	0,87	neutral	4,54	neutral	0,47	deleterious	-3,73	low_impact	1,64	neutral	0,93	neutral	0,52	deleterious	3,38	23	0,17	0,45	neutral	0,32	disease	0,86	disease	0,56	neutral	0,23	5	deleterious	0,98	neutral	0,45	neutral	-2	deleterious	0,81	low_impact	-2,34	medium_impact	0,67	medium_impact	0,24	0,63	0,8	NA	NA	N	0,47	N	0,93	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9182	9182	G	A	MI.1396	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	656	219	S	N	aGc/aAc	5,68	1	0,01	probably_damaging	0,98	neutral	0,07	neutral	4,29	deleterious	-3,16	neutral	-2,38	medium_impact	2,4	neutral	0,95	neutral	0,6	deleterious	3,73	23,3	0,56	0,65	NA	NA	disease	0,7	disease	0,7	disease	0,66	3	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,79	low_impact	-2,36	medium_impact	-0,34	medium_impact	0,96	0,72	0,9	48,23	7,68	P	0,55	P	0,88	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5040	5040	A	T	MI.13960	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	571	191	M	L	Ata/Tta	0,49	0,02	0	benign	0	neutral	1	neutral	4,65	neutral	1,97	neutral	-0,95	neutral_impact	-0,42	neutral	0,89	neutral	0,96	neutral	-0,41	0,37	0,26	0,45	neutral	0,27	disease	0,62	neutral	0,37	neutral	0,2	6	neutral	0	deleterious	1	neutral	-6	neutral	0,15	medium_impact	1,95	high_impact	1,87	low_impact	-1,5	0,58	0,8	9,22	7,95	N	0,33	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5040	5040	A	C	MI.13961	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	571	191	M	L	Ata/Cta	0,49	0,02	0	benign	0	neutral	1	neutral	4,65	neutral	1,97	neutral	-0,95	neutral_impact	-0,42	neutral	0,89	neutral	0,96	neutral	-0,48	0,25	0,26	0,45	neutral	0,27	disease	0,62	neutral	0,37	neutral	0,2	6	neutral	0	deleterious	1	neutral	-6	neutral	0,15	medium_impact	1,95	high_impact	1,87	low_impact	-1,5	0,58	0,8	9,22	7,95	N	0,32	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5040	5040	A	G	MI.13962	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	571	191	M	V	Ata/Gta	0,49	0,02	0	benign	0,01	neutral	0,6	neutral	4,57	neutral	0,17	neutral	-0,56	neutral_impact	0,31	neutral	0,92	neutral	0,98	neutral	-1,18	0,01	0,24	0,45	neutral	0,29	disease	0,59	neutral	0,36	neutral	0,21	6	neutral	0,39	deleterious	0,8	neutral	-6	neutral	0,14	medium_impact	1,03	medium_impact	0,31	medium_impact	-0,88	0,56	0,8	9,22	7,95	N	0,29	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5041	5041	T	C	MI.13963	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	572	191	M	T	aTa/aCa	-0,89	0	0,01	benign	0,01	neutral	0,51	neutral	4,47	neutral	-0,35	neutral	0,06	neutral_impact	-0,1	neutral	0,96	neutral	0,99	neutral	-1,64	0	0,11	0,4	neutral	0,24	neutral	0,41	neutral	0,37	neutral	0,42	2	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,22	low_impact	-1,23	0,33	0,8	9,22	7,95	N	0,34	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5041	5041	T	A	MI.13964	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	572	191	M	K	aTa/aAa	-0,89	0	0,01	benign	0,27	neutral	0,32	neutral	4,42	deleterious	-3,37	neutral	-2,13	medium_impact	2,58	neutral	0,87	neutral	0,42	deleterious	2,42	18,97	0,02	0,35	disease	0,61	disease	0,8	disease	0,64	disease	0,74	5	neutral	0,61	deleterious	0,53	neutral	-3	deleterious	0,56	medium_impact	-0,4	medium_impact	0,03	medium_impact	1,03	0,37	0,8	9,22	7,95	N	0,3	N	0,67	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5042	5042	A	C	MI.13965	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	573	191	M	I	atA/atC	-0,89	0	0	benign	0,09	neutral	0,72	neutral	4,64	neutral	0,02	neutral	-1,14	neutral_impact	0,14	neutral	0,84	neutral	0,98	neutral	-1	0,02	0,24	0,45	neutral	0,22	neutral	0,48	neutral	0,29	neutral	0,35	3	neutral	0,18	deleterious	0,82	neutral	-6	neutral	0,26	medium_impact	0,12	medium_impact	0,44	low_impact	-1,03	0,65	0,8	9,22	7,95	N	0,29	N	0,3	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5042	5042	A	T	MI.13966	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	573	191	M	I	atA/atT	-0,89	0	0	benign	0,09	neutral	0,72	neutral	4,64	neutral	0,02	neutral	-1,14	neutral_impact	0,14	neutral	0,84	neutral	0,98	neutral	-0,83	0,04	0,24	0,45	neutral	0,22	neutral	0,48	neutral	0,29	neutral	0,35	3	neutral	0,18	deleterious	0,82	neutral	-6	neutral	0,26	medium_impact	0,12	medium_impact	0,44	low_impact	-1,03	0,65	0,8	9,22	7,95	N	0,3	N	0,3	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5043	5043	G	A	MI.13967	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	574	192	A	T	Gca/Aca	-5,04	0	0	benign	0,09	neutral	0,37	neutral	4,54	neutral	-1,92	neutral	-2,38	low_impact	0,98	neutral	0,94	neutral	0,92	deleterious	2,84	21,6	0,11	0,4	disease	0,68	disease	0,52	neutral	0,3	neutral	0,27	5	neutral	0,58	deleterious	0,64	neutral	-6	neutral	0,3	medium_impact	0,12	medium_impact	0,08	medium_impact	-0,32	0,74	0,85	NA	NA	N	0,38	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5043	5043	G	T	MI.13968	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	574	192	A	S	Gca/Tca	-5,04	0	0	benign	0,42	neutral	0,67	neutral	4,57	neutral	-2,56	neutral	-1,98	low_impact	0,86	neutral	0,66	neutral	0,92	deleterious	2,35	18,5	0,19	0,45	disease	0,69	disease	0,54	neutral	0,28	neutral	0,27	5	neutral	0,34	deleterious	0,63	neutral	-6	deleterious	0,62	medium_impact	-0,67	medium_impact	0,38	medium_impact	-0,42	0,43	0,8	NA	NA	N	0,31	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5043	5043	G	C	MI.13969	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	574	192	A	P	Gca/Cca	-5,04	0	0	possibly_damaging	0,9	neutral	0,17	neutral	4,48	deleterious	-4,58	deleterious	-3,83	medium_impact	2,22	neutral	0,87	neutral	0,34	deleterious	3,79	23,4	0,03	0,35	disease	0,87	disease	0,85	disease	0,64	disease	0,67	3	neutral	0,94	neutral	0,14	NA	0	deleterious	0,86	low_impact	-1,67	medium_impact	-0,17	medium_impact	0,72	0,55	0,8	NA	NA	N	0,39	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9182	9182	G	T	MI.1397	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	656	219	S	I	aGc/aTc	5,68	1	0,01	probably_damaging	0,99	neutral	0,06	neutral	4,45	neutral	-1	deleterious	-5,23	medium_impact	2,25	neutral	0,84	neutral	0,6	deleterious	4,2	23,9	0,27	0,65	NA	NA	disease	0,79	disease	0,63	disease	0,54	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,8	low_impact	-2,65	medium_impact	-0,38	medium_impact	0,83	0,77	0,9	48,23	7,68	N	0,48	N	1	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5044	5044	C	G	MI.13970	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	575	192	A	G	gCa/gGa	-1,12	0	0	possibly_damaging	0,7	neutral	0,31	neutral	4,66	neutral	-1,13	deleterious	-3,33	low_impact	1,92	neutral	0,9	neutral	0,62	deleterious	3,93	23,5	0,13	0,4	disease	0,83	disease	0,58	neutral	0,49	disease	0,52	0	neutral	0,76	neutral	0,31	neutral	-3	deleterious	0,71	low_impact	-1,13	medium_impact	0,02	medium_impact	0,47	0,58	0,8	NA	NA	N	0,43	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5044	5044	C	A	MI.13971	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	575	192	A	E	gCa/gAa	-1,12	0	0	possibly_damaging	0,8	neutral	0,21	neutral	4,49	deleterious	-4,49	deleterious	-3,79	medium_impact	3,12	neutral	0,91	neutral	0,45	deleterious	4,49	24,3	0,03	0,35	disease	0,85	disease	0,83	disease	0,63	disease	0,67	3	neutral	0,88	neutral	0,21	NA	0	deleterious	0,83	low_impact	-1,35	medium_impact	-0,11	medium_impact	1,48	0,37	0,8	NA	NA	N	0,47	N	0,91	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5044	5044	C	T	MI.13972	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	575	192	A	V	gCa/gTa	-1,12	0	0	benign	0,42	neutral	0,65	neutral	4,63	neutral	-0,47	neutral	-2,41	low_impact	1,16	neutral	0,77	neutral	0,92	deleterious	2,99	22,2	0,12	0,4	neutral	0,37	disease	0,62	neutral	0,32	neutral	0,21	6	neutral	0,35	deleterious	0,62	neutral	-6	deleterious	0,53	medium_impact	-0,67	medium_impact	0,36	medium_impact	-0,17	0,68	0,85	NA	NA	N	0,25	N	0,52	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5046	5046	G	C	MI.13973	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	577	193	V	L	Gtt/Ctt	-4,11	0	0,04	benign	0,22	neutral	0,99	neutral	4,69	neutral	0,11	neutral	-1,38	low_impact	0,92	neutral	0,89	neutral	0,5	deleterious	1,84	15,21	0,12	0,4	neutral	0,38	disease	0,75	disease	0,57	disease	0,67	3	neutral	0,2	deleterious	0,89	neutral	-6	neutral	0,42	medium_impact	-0,29	medium_impact	1,32	medium_impact	-0,37	0,51	0,8	NA	NA	N	0,23	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5046	5046	G	A	MI.13974	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	577	193	V	I	Gtt/Att	-4,11	0	0,04	benign	0,02	neutral	0,83	neutral	4,84	neutral	-0,09	neutral	0,37	neutral_impact	-0,83	neutral	0,88	neutral	0,94	neutral	-1,05	0,01	0,29	0,45	neutral	0,35	neutral	0,12	neutral	0,28	neutral	0,21	6	neutral	0,12	deleterious	0,91	neutral	-6	neutral	0,13	medium_impact	0,75	medium_impact	0,59	low_impact	-1,84	0,66	0,8	NA	NA	N	0,3	N	0,18	polymorphism	1	0,01	rs878927053	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5046	5046	G	T	MI.13975	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	577	193	V	F	Gtt/Ttt	-4,11	0	0,04	possibly_damaging	0,81	neutral	0,72	neutral	4,59	neutral	-1,24	deleterious	-3,21	medium_impact	2,08	neutral	0,85	neutral	0,46	deleterious	3,65	23,2	0,05	0,35	neutral	0,36	disease	0,88	disease	0,63	disease	0,74	5	neutral	0,77	neutral	0,46	NA	0	deleterious	0,72	low_impact	-1,37	medium_impact	0,44	medium_impact	0,61	0,4	0,8	NA	NA	N	0,21	N	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5047	5047	T	G	MI.13976	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	578	193	V	G	gTt/gGt	-0,43	0	0	possibly_damaging	0,66	neutral	0,38	neutral	4,52	neutral	0,85	deleterious	-6,29	low_impact	0,92	neutral	0,89	neutral	0,45	deleterious	3,75	23,3	0,05	0,35	disease	0,5	disease	0,79	disease	0,63	disease	0,7	4	neutral	0,69	neutral	0,36	neutral	-3	deleterious	0,66	low_impact	-1,06	medium_impact	0,09	medium_impact	-0,37	0,26	0,8	NA	NA	N	0,32	N	0,86	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5047	5047	T	C	MI.13977	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	578	193	V	A	gTt/gCt	-0,43	0	0	benign	0,33	neutral	0,56	neutral	4,68	neutral	0,96	deleterious	-3,51	neutral_impact	0,22	neutral	0,88	neutral	0,77	deleterious	0,86	9,84	0,09	0,35	disease	0,57	disease	0,62	neutral	0,45	neutral	0,2	6	neutral	0,35	deleterious	0,62	neutral	-6	deleterious	0,49	medium_impact	-0,52	medium_impact	0,27	medium_impact	-0,96	0,17	0,8	NA	NA	N	0,26	N	0,63	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5047	5047	T	A	MI.13978	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	578	193	V	D	gTt/gAt	-0,43	0	0	possibly_damaging	0,81	neutral	0,26	neutral	4,51	deleterious	-4,61	deleterious	-5,57	medium_impact	2,62	neutral	0,84	neutral	0,38	deleterious	4,56	24,4	0,02	0,35	disease	0,88	disease	0,89	disease	0,72	disease	0,65	3	neutral	0,86	neutral	0,23	NA	0	deleterious	0,8	low_impact	-1,37	medium_impact	-0,04	medium_impact	1,06	0,14	0,8	NA	NA	N	0,28	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5049	5049	C	G	MI.13979	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	580	194	L	V	Cta/Gta	-9,18	0	0,03	possibly_damaging	0,79	neutral	0,59	neutral	4,37	neutral	-1,8	neutral	-1,39	low_impact	1,8	neutral	0,91	neutral	0,95	deleterious	2,31	18,22	0,3	0,45	disease	0,72	disease	0,58	neutral	0,41	neutral	0,24	5	neutral	0,76	neutral	0,4	neutral	-3	deleterious	0,72	low_impact	-1,32	medium_impact	0,3	medium_impact	0,37	0,61	0,8	1,15	7,21	N	0,24	N	0,51	polymorphism	1	0,03	rs28494478	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9184	9184	C	A	MI.1398	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	658	220	L	I	Ctc/Atc	-0,1	0,34	0	probably_damaging	0,99	neutral	0,09	neutral	4,21	neutral	-0,71	neutral	-1,77	medium_impact	2,21	damaging	0,57	neutral	0,57	deleterious	4,16	23,8	0,44	0,65	NA	NA	neutral	0,41	disease	0,65	neutral	0,36	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,8	low_impact	-2,65	medium_impact	-0,28	medium_impact	0,8	0,73	0,9	50	8,8	N	0,38	N	0,87	disease_causing	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5049	5049	C	A	MI.13980	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	580	194	L	M	Cta/Ata	-9,18	0	0,03	possibly_damaging	0,58	neutral	0,28	neutral	4,3	deleterious	-3,49	neutral	-0,97	neutral_impact	0,48	neutral	0,94	neutral	0,92	deleterious	2,23	17,71	0,27	0,45	disease	0,79	neutral	0,39	neutral	0,33	disease	0,65	3	neutral	0,73	neutral	0,35	neutral	-3	deleterious	0,65	medium_impact	-0,93	medium_impact	-0,02	medium_impact	-0,74	0,36	0,8	1,15	7,21	N	0,44	N	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5050	5050	T	C	MI.13981	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	581	194	L	P	cTa/cCa	-7,11	0	0	probably_damaging	0,99	neutral	0,2	neutral	4,22	deleterious	-5,92	deleterious	-5,44	medium_impact	3,27	neutral	0,74	neutral	0,34	deleterious	3,84	23,4	0,02	0,35	disease	0,53	disease	0,88	disease	0,74	disease	0,73	5	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,82	low_impact	-2,62	medium_impact	-0,13	medium_impact	1,61	0,24	0,8	1,15	7,21	N	0,33	N	0,96	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5050	5050	T	A	MI.13982	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	581	194	L	Q	cTa/cAa	-7,11	0	0	probably_damaging	0,98	neutral	0,37	neutral	4,23	deleterious	-5,4	deleterious	-4,67	medium_impact	2,93	neutral	0,85	neutral	0,49	deleterious	3,99	23,6	0,03	0,35	disease	0,93	disease	0,8	disease	0,62	disease	0,68	4	deleterious	0,98	neutral	0,2	deleterious	1	deleterious	0,84	low_impact	-2,34	medium_impact	0,08	medium_impact	1,32	0,32	0,8	1,15	7,21	N	0,3	N	0,98	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5050	5050	T	G	MI.13983	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	581	194	L	R	cTa/cGa	-7,11	0	0	probably_damaging	0,98	neutral	0,32	neutral	4,23	deleterious	-5,36	deleterious	-4,81	medium_impact	3,27	neutral	0,8	neutral	0,38	deleterious	4,07	23,7	0,01	0,35	disease	0,93	disease	0,92	disease	0,75	disease	0,64	3	neutral	0,98	neutral	0,17	deleterious	1	deleterious	0,91	low_impact	-2,34	medium_impact	0,03	medium_impact	1,61	0,25	0,8	1,15	7,21	N	0,34	N	1	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5052	5052	C	G	MI.13984	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	583	195	P	A	Ccg/Gcg	-6,88	0	0	benign	0	neutral	0,48	neutral	4,77	neutral	2,12	neutral	0,93	neutral_impact	0,12	neutral	0,84	neutral	0,94	neutral	1,01	10,71	0,23	0,45	neutral	0,41	neutral	0,31	neutral	0,42	neutral	0,43	1	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,19	low_impact	-1,04	0,66	0,8	15,27	10,13	N	0,37	N	0,64	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5052	5052	C	A	MI.13985	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	583	195	P	T	Ccg/Acg	-6,88	0	0	benign	0,01	neutral	0,42	neutral	4,69	neutral	0,23	neutral	2,03	neutral_impact	-0,76	neutral	0,98	neutral	0,98	neutral	1,4	12,8	0,19	0,45	disease	0,59	neutral	0,29	neutral	0,25	disease	0,54	1	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	0,13	low_impact	-1,78	0,57	0,8	15,27	10,13	N	0,36	N	0,35	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5052	5052	C	T	MI.13986	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	583	195	P	S	Ccg/Tcg	-6,88	0	0	benign	0,12	neutral	0,45	neutral	4,87	neutral	0,86	neutral	0,75	neutral_impact	-0,22	neutral	0,75	neutral	0,93	deleterious	2,12	16,97	0,24	0,45	disease	0,53	neutral	0,29	neutral	0,3	neutral	0,39	2	neutral	0,48	deleterious	0,67	neutral	-6	neutral	0,26	medium_impact	-0,01	medium_impact	0,16	low_impact	-1,33	0,26	0,8	15,27	10,13	N	0,37	N	0,75	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5053	5053	C	A	MI.13987	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	584	195	P	Q	cCg/cAg	-5,27	0	0	benign	0,43	neutral	0,31	neutral	4,66	neutral	-0,94	neutral	-0,39	neutral_impact	-0,17	neutral	0,82	neutral	0,76	deleterious	2,69	20,8	0,14	0,4	disease	0,67	neutral	0,34	neutral	0,36	disease	0,61	2	neutral	0,64	neutral	0,44	neutral	-6	deleterious	0,52	medium_impact	-0,69	medium_impact	0,02	low_impact	-1,29	0,4	0,8	15,27	10,13	N	0,37	N	0,87	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5053	5053	C	T	MI.13988	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	584	195	P	L	cCg/cTg	-5,27	0	0	benign	0,05	neutral	0,7	neutral	4,66	neutral	0,59	neutral	0,48	neutral_impact	-0,64	neutral	0,87	neutral	0,94	deleterious	1,97	16,05	0,11	0,4	disease	0,7	disease	0,52	neutral	0,44	neutral	0,29	4	neutral	0,23	deleterious	0,83	neutral	-6	neutral	0,22	medium_impact	0,37	medium_impact	0,41	low_impact	-1,68	0,62	0,8	15,27	10,13	N	0,25	N	0,84	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5053	5053	C	G	MI.13989	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	584	195	P	R	cCg/cGg	-5,27	0	0	benign	0,3	neutral	0,32	neutral	4,66	neutral	-1,52	neutral	-0,82	medium_impact	1,98	neutral	0,91	neutral	0,41	deleterious	1,92	15,73	0,11	0,4	disease	0,78	disease	0,72	disease	0,63	disease	0,7	4	neutral	0,61	deleterious	0,51	neutral	-3	deleterious	0,54	medium_impact	-0,46	medium_impact	0,03	medium_impact	0,52	0,46	0,8	15,27	10,13	N	0,31	N	0,92	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9184	9184	C	G	MI.1399	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	658	220	L	V	Ctc/Gtc	-0,1	0,34	0	probably_damaging	0,99	deleterious	0	neutral	4,32	neutral	0,6	deleterious	-2,66	medium_impact	2,72	damaging	0,32	neutral	0,44	deleterious	3,54	23,1	0,46	0,65	NA	NA	neutral	0,44	disease	0,65	neutral	0,41	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-2,65	low_impact	-1,4	medium_impact	1,23	0,76	0,9	50	8,8	P	0,68	P	0,87	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5055	5055	T	C	MI.13990	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	586	196	Y	H	Tac/Cac	-8,95	0	0	benign	0,19	neutral	0,37	neutral	4,61	neutral	-2,64	deleterious	-4,47	medium_impact	2,17	neutral	0,88	neutral	0,28	deleterious	3,6	23,2	0,17	0,45	disease	0,86	disease	0,85	disease	0,7	disease	0,57	1	neutral	0,56	deleterious	0,59	neutral	-3	deleterious	0,46	medium_impact	-0,22	medium_impact	0,08	medium_impact	0,68	0,31	0,8	NA	NA	N	0,31	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5055	5055	T	A	MI.13991	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	586	196	Y	N	Tac/Aac	-8,95	0	0	probably_damaging	0,95	neutral	0,27	neutral	4,65	neutral	-2,48	deleterious	-8,03	low_impact	1,88	neutral	0,87	damaging	0,14	deleterious	4,07	23,7	0,12	0,4	disease	0,84	disease	0,87	disease	0,67	disease	0,63	3	neutral	0,96	neutral	0,16	neutral	-2	deleterious	0,81	low_impact	-1,97	medium_impact	-0,03	medium_impact	0,44	0,23	0,8	NA	NA	N	0,35	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5055	5055	T	G	MI.13992	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	586	196	Y	D	Tac/Gac	-8,95	0	0	probably_damaging	0,97	neutral	0,14	neutral	4,61	deleterious	-3,13	deleterious	-8,85	medium_impact	3,07	neutral	0,9	damaging	0,11	deleterious	4,03	23,6	0,06	0,35	disease	0,9	disease	0,91	disease	0,77	disease	0,67	3	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,81	low_impact	-2,18	medium_impact	-0,23	medium_impact	1,44	0,2	0,8	NA	NA	N	0,48	N	0,97	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5056	5056	A	G	MI.13993	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	587	196	Y	C	tAc/tGc	2,79	0,6	0	probably_damaging	0,99	neutral	0,12	neutral	4,61	neutral	-2,31	deleterious	-7,94	medium_impact	2,03	neutral	0,76	damaging	0,1	deleterious	3,59	23,2	0,06	0,35	disease	0,75	disease	0,92	disease	0,71	disease	0,71	4	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,8	low_impact	-2,62	medium_impact	-0,27	medium_impact	0,56	0,09	0,8	NA	NA	N	0,35	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5056	5056	A	T	MI.13994	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	587	196	Y	F	tAc/tTc	2,79	0,6	0	possibly_damaging	0,9	neutral	0,68	neutral	4,66	neutral	0,14	deleterious	-2,75	neutral_impact	0,66	neutral	0,89	neutral	0,91	deleterious	2,2	17,51	0,31	0,45	neutral	0,46	disease	0,62	neutral	0,38	neutral	0,23	5	neutral	0,88	neutral	0,39	neutral	-3	deleterious	0,73	low_impact	-1,67	medium_impact	0,39	medium_impact	-0,59	0,5	0,8	NA	NA	N	0,31	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5056	5056	A	C	MI.13995	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	587	196	Y	S	tAc/tCc	2,79	0,6	0	probably_damaging	0,95	neutral	0,47	neutral	4,64	neutral	-0,89	deleterious	-7,91	low_impact	1,49	neutral	0,85	damaging	0,13	deleterious	3,8	23,4	0,1	0,4	disease	0,64	disease	0,88	disease	0,66	disease	0,7	4	neutral	0,94	neutral	0,26	neutral	-2	deleterious	0,78	low_impact	-1,97	medium_impact	0,18	medium_impact	0,11	0,21	0,8	NA	NA	N	0,33	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5058	5058	A	C	MI.13996	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	589	197	N	H	Aac/Cac	-3,19	0	0	probably_damaging	0,99	neutral	0,52	neutral	4,48	neutral	-2,75	deleterious	-4,14	medium_impact	2,86	neutral	0,88	damaging	0,13	deleterious	3,05	22,4	0,32	0,5	disease	0,95	disease	0,8	disease	0,7	disease	0,7	4	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,8	low_impact	-2,62	medium_impact	0,23	medium_impact	1,26	0,17	0,8	NA	NA	N	0,27	N	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5058	5058	A	T	MI.13997	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	589	197	N	Y	Aac/Tac	-3,19	0	0	probably_damaging	0,99	neutral	1	neutral	4,47	deleterious	-3,37	deleterious	-6,68	medium_impact	2,45	neutral	0,88	damaging	0,24	deleterious	3,57	23,1	0,11	0,4	disease	0,96	disease	0,85	disease	0,54	disease	0,64	3	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,83	low_impact	-2,62	high_impact	1,87	medium_impact	0,92	0,21	0,8	NA	NA	N	0,23	N	0,65	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5058	5058	A	G	MI.13998	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	589	197	N	D	Aac/Gac	-3,19	0	0	benign	0,14	neutral	0,2	neutral	4,57	neutral	-1,12	deleterious	-3,82	medium_impact	2,05	neutral	0,93	damaging	0,27	deleterious	3,73	23,3	0,48	0,55	disease	0,93	disease	0,72	disease	0,6	disease	0,66	3	neutral	0,77	deleterious	0,53	neutral	-3	neutral	0,35	medium_impact	-0,08	medium_impact	-0,13	medium_impact	0,58	0,4	0,8	NA	NA	N	0,39	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5059	5059	A	G	MI.13999	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	590	197	N	S	aAc/aGc	0,26	0	0	benign	0,34	neutral	0,44	neutral	4,58	neutral	-0,15	deleterious	-3,76	low_impact	0,83	neutral	0,87	neutral	0,79	deleterious	2,47	19,28	0,44	0,55	neutral	0,47	neutral	0,42	neutral	0,41	neutral	0,43	1	neutral	0,48	deleterious	0,55	neutral	-6	neutral	0,42	medium_impact	-0,53	medium_impact	0,15	medium_impact	-0,45	0,28	0,8	NA	NA	N	0,33	N	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8532	8532	C	A	MI.14	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	6	2	N	K	aaC/aaA	1,75	0,87	0	probably_damaging	0,97	neutral	0,07	neutral	4,69	neutral	0,02	deleterious	-3,41	medium_impact	2,6	neutral	0,87	neutral	0,44	deleterious	4,56	24,4	0,78	0,8	disease	0,51	neutral	0,42	neutral	0,25	neutral	0,38	3	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,68	low_impact	-2,19	medium_impact	-0,34	medium_impact	1,13	0,26	0,9	41,59	7,23	N	0,4	N	1	disease_causing	0,89	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8593	8593	A	G	MI.140	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	67	23	I	V	Atc/Gtc	-8,2	0	0	benign	0,01	neutral	1	neutral	4,44	neutral	0,42	neutral	-0,13	low_impact	0,88	neutral	0,94	neutral	0,84	neutral	-0,45	0,28	0,6	0,7	neutral	0,29	neutral	0,32	neutral	0,5	neutral	0,45	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,14	high_impact	1,98	medium_impact	-0,34	0,33	0,9	19,03	10,37	N	0,27	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9184	9184	C	T	MI.1400	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	658	220	L	F	Ctc/Ttc	-0,1	0,34	0	probably_damaging	1	neutral	0,08	neutral	4,16	neutral	-2,56	deleterious	-3,54	medium_impact	2,84	damaging	0,37	neutral	0,45	deleterious	4,12	23,8	0,46	0,65	NA	NA	disease	0,55	neutral	0,46	neutral	0,46	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,31	medium_impact	1,34	0,75	0,9	50	8,8	P	0,62	P	0,97	disease_causing	1	0,09	rs879233310	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5059	5059	A	T	MI.14000	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	590	197	N	I	aAc/aTc	0,26	0	0	probably_damaging	0,97	neutral	0,42	neutral	4,49	deleterious	-3,29	deleterious	-7,5	medium_impact	3	neutral	0,87	damaging	0,12	deleterious	4,47	24,2	0,13	0,4	disease	0,92	disease	0,91	disease	0,58	disease	0,62	2	neutral	0,97	neutral	0,23	deleterious	1	deleterious	0,83	low_impact	-2,18	medium_impact	0,13	medium_impact	1,38	0,15	0,8	NA	NA	N	0,29	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5059	5059	A	C	MI.14001	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	590	197	N	T	aAc/aCc	0,26	0	0	possibly_damaging	0,77	neutral	0,38	neutral	4,63	neutral	-1,01	deleterious	-4,8	medium_impact	2,23	neutral	0,94	damaging	0,17	deleterious	3,89	23,5	0,28	0,45	disease	0,63	disease	0,81	disease	0,59	disease	0,55	1	neutral	0,78	neutral	0,31	NA	0	deleterious	0,72	low_impact	-1,28	medium_impact	0,09	medium_impact	0,73	0,28	0,8	NA	NA	N	0,35	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5060	5060	C	G	MI.14002	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	591	197	N	K	aaC/aaG	-0,2	0	0	possibly_damaging	0,89	neutral	0,28	neutral	4,56	neutral	-1,06	deleterious	-4,85	medium_impact	2,65	neutral	0,86	damaging	0,12	deleterious	4,06	23,7	0,27	0,45	disease	0,91	disease	0,87	disease	0,71	disease	0,64	3	neutral	0,91	neutral	0,2	NA	0	deleterious	0,81	low_impact	-1,63	medium_impact	-0,02	medium_impact	1,09	0,29	0,8	NA	NA	N	0,29	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5060	5060	C	A	MI.14003	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	591	197	N	K	aaC/aaA	-0,2	0	0	possibly_damaging	0,89	neutral	0,28	neutral	4,56	neutral	-1,06	deleterious	-4,85	medium_impact	2,65	neutral	0,86	damaging	0,12	deleterious	4,51	24,3	0,27	0,45	disease	0,91	disease	0,87	disease	0,71	disease	0,64	3	neutral	0,91	neutral	0,2	NA	0	deleterious	0,81	low_impact	-1,63	medium_impact	-0,02	medium_impact	1,09	0,29	0,8	NA	NA	N	0,3	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5061	5061	C	G	MI.14004	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	592	198	P	A	Cct/Gct	-2,27	0	0	probably_damaging	1	neutral	0,51	neutral	4,76	neutral	0,14	deleterious	-5,96	medium_impact	2,7	neutral	0,93	neutral	0,57	deleterious	3,13	22,6	0,23	0,45	disease	0,55	disease	0,7	disease	0,73	disease	0,67	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,22	medium_impact	1,13	0,7	0,85	NA	NA	N	0,34	N	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5061	5061	C	A	MI.14005	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	592	198	P	T	Cct/Act	-2,27	0	0	probably_damaging	1	neutral	0,39	neutral	4,67	neutral	0,78	deleterious	-5,7	medium_impact	2,06	neutral	0,9	neutral	0,71	deleterious	3,88	23,5	0,23	0,45	disease	0,53	disease	0,77	neutral	0,46	neutral	0,17	7	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	0,1	medium_impact	0,59	0,62	0,8	NA	NA	N	0,36	N	0,88	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5061	5061	C	T	MI.14006	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	592	198	P	S	Cct/Tct	-2,27	0	0	probably_damaging	1	neutral	0,41	neutral	4,77	neutral	0,3	deleterious	-5,87	medium_impact	2,01	neutral	0,95	neutral	0,58	deleterious	3,87	23,5	0,33	0,5	disease	0,64	disease	0,81	disease	0,61	disease	0,54	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,12	medium_impact	0,55	0,16	0,8	NA	NA	N	0,35	N	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5062	5062	C	T	MI.14007	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	593	198	P	L	cCt/cTt	1,18	0,06	0	probably_damaging	1	neutral	0,66	neutral	4,72	neutral	-1,13	deleterious	-7,88	medium_impact	2,1	neutral	0,91	neutral	0,49	deleterious	4,33	24	0,17	0,45	neutral	0,39	disease	0,88	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,37	medium_impact	0,62	0,68	0,85	NA	NA	N	0,33	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5062	5062	C	G	MI.14008	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	593	198	P	R	cCt/cGt	1,18	0,06	0	probably_damaging	1	neutral	0,34	neutral	4,66	neutral	-1,43	deleterious	-6,98	medium_impact	3,4	neutral	0,88	neutral	0,43	deleterious	3,64	23,2	0,08	0,35	disease	0,84	disease	0,91	disease	0,81	disease	0,67	3	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	0,05	medium_impact	1,72	0,35	0,8	NA	NA	N	0,49	N	0,56	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5062	5062	C	A	MI.14009	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	593	198	P	H	cCt/cAt	1,18	0,06	0	probably_damaging	1	neutral	0,54	neutral	4,63	neutral	-2,6	deleterious	-7,12	medium_impact	2,77	neutral	0,93	neutral	0,44	deleterious	3,98	23,6	0,1	0,4	disease	0,88	disease	0,86	disease	0,74	disease	0,63	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,25	medium_impact	1,19	0,28	0,8	NA	NA	N	0,35	N	0,71	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9185	9185	T	C	MI.1401	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	659	220	L	P	cTc/cCc	0,82	0,48	0	probably_damaging	1	deleterious	0	neutral	4,08	deleterious	-4,18	deleterious	-6,22	high_impact	4,3	damaging	0,2	neutral	0,42	deleterious	3,99	23,6	0,2	0,65	NA	NA	disease	0,67	disease	0,76	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,59	0,48	0,9	50	8,8	P	0,94	P	1	disease_causing_automatic	1	0,32	rs199476138	Pathogenic	Leigh_syndrome	RCV000010282.5	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	T9185C	Leigh Disease/Ataxia syndromes/NARP-like disease	+	+	Cfrm	10
chrM	5064	5064	A	G	MI.14010	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	595	199	N	D	Aac/Gac	-11,25	0	0	benign	0,01	neutral	0,19	neutral	4,62	neutral	-0,93	neutral	-1,36	medium_impact	2,04	neutral	0,89	neutral	0,67	deleterious	0,85	9,79	0,59	0,65	disease	0,83	disease	0,58	neutral	0,33	neutral	0,37	3	neutral	0,81	deleterious	0,59	neutral	-3	neutral	0,23	medium_impact	1,03	medium_impact	-0,14	medium_impact	0,57	0,32	0,8	1,15	8,22	N	0,39	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5064	5064	A	C	MI.14011	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	595	199	N	H	Aac/Cac	-11,25	0	0	possibly_damaging	0,86	neutral	0,5	neutral	4,61	neutral	-1,31	neutral	-2,44	low_impact	0,92	neutral	0,86	neutral	0,68	deleterious	2,91	21,9	0,39	0,5	disease	0,77	disease	0,54	neutral	0,37	neutral	0,27	5	neutral	0,84	neutral	0,32	neutral	-3	deleterious	0,71	low_impact	-1,52	medium_impact	0,21	medium_impact	-0,37	0,22	0,8	1,15	8,22	N	0,25	N	0,33	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5064	5064	A	T	MI.14012	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	595	199	N	Y	Aac/Tac	-11,25	0	0	possibly_damaging	0,8	neutral	1	neutral	4,77	neutral	1,88	deleterious	-3,27	low_impact	1,21	neutral	0,92	neutral	0,58	deleterious	3,65	23,2	0,15	0,4	disease	0,64	disease	0,7	disease	0,54	disease	0,6	2	neutral	0,8	deleterious	0,6	neutral	-3	deleterious	0,7	low_impact	-1,35	high_impact	1,87	medium_impact	-0,13	0,28	0,8	1,15	8,22	N	0,26	N	0,65	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5065	5065	A	G	MI.14013	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	596	199	N	S	aAc/aGc	-1,81	0	0	benign	0,2	neutral	0,48	neutral	4,71	neutral	1,25	neutral	-0,19	neutral_impact	0,32	neutral	0,87	neutral	0,99	neutral	-0,45	0,29	0,52	0,6	neutral	0,46	neutral	0,38	neutral	0,27	neutral	0,46	1	neutral	0,42	deleterious	0,64	neutral	-6	neutral	0,3	medium_impact	-0,25	medium_impact	0,19	medium_impact	-0,88	0,12	0,8	1,15	8,22	N	0,41	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5065	5065	A	C	MI.14014	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	596	199	N	T	aAc/aCc	-1,81	0	0	benign	0,02	neutral	0,44	neutral	4,69	neutral	0,89	neutral	1,24	neutral_impact	-0,18	neutral	0,9	neutral	0,97	neutral	-0,97	0,02	0,33	0,5	disease	0,51	neutral	0,36	neutral	0,21	neutral	0,33	3	neutral	0,54	deleterious	0,71	neutral	-6	neutral	0,16	medium_impact	0,75	medium_impact	0,15	low_impact	-1,3	0,37	0,8	1,15	8,22	N	0,36	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5065	5065	A	T	MI.14015	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	596	199	N	I	aAc/aTc	-1,81	0	0	benign	0,41	neutral	0,44	neutral	4,79	neutral	2,05	deleterious	-2,88	low_impact	1,93	neutral	0,9	neutral	0,65	deleterious	3,69	23,3	0,16	0,45	neutral	0,45	disease	0,79	neutral	0,5	disease	0,56	1	neutral	0,5	deleterious	0,52	neutral	-6	deleterious	0,56	medium_impact	-0,65	medium_impact	0,15	medium_impact	0,48	0,18	0,8	1,15	8,22	N	0,34	N	0,63	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5066	5066	C	G	MI.14016	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	597	199	N	K	aaC/aaG	0,03	0	0	benign	0,36	neutral	0,3	neutral	4,67	neutral	0,64	neutral	-1,97	neutral_impact	0,45	neutral	0,8	neutral	0,64	neutral	1,19	11,71	0,48	0,55	disease	0,7	neutral	0,32	neutral	0,31	disease	0,64	3	neutral	0,64	deleterious	0,47	neutral	-6	deleterious	0,49	medium_impact	-0,57	medium_impact	0	medium_impact	-0,77	0,49	0,8	1,15	8,22	N	0,34	N	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5066	5066	C	A	MI.14017	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	597	199	N	K	aaC/aaA	0,03	0	0	benign	0,36	neutral	0,3	neutral	4,67	neutral	0,64	neutral	-1,97	neutral_impact	0,45	neutral	0,8	neutral	0,64	neutral	1,72	14,52	0,48	0,55	disease	0,7	neutral	0,32	neutral	0,31	disease	0,64	3	neutral	0,64	deleterious	0,47	neutral	-6	deleterious	0,49	medium_impact	-0,57	medium_impact	0	medium_impact	-0,77	0,49	0,8	1,15	8,22	N	0,34	N	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5067	5067	A	C	MI.14018	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	598	200	M	L	Ata/Cta	-6,65	0	0	benign	0,01	neutral	1	neutral	4,83	neutral	2,05	neutral	-0,22	neutral_impact	-0,74	neutral	0,9	neutral	0,96	neutral	-1,49	0	0,39	0,5	neutral	0,38	neutral	0,19	neutral	0,29	neutral	0,34	3	neutral	0,01	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,03	high_impact	1,87	low_impact	-1,77	0,25	0,8	1,73	8,56	N	0,35	N	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5067	5067	A	T	MI.14019	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	598	200	M	L	Ata/Tta	-6,65	0	0	benign	0,01	neutral	1	neutral	4,83	neutral	2,05	neutral	-0,22	neutral_impact	-0,74	neutral	0,9	neutral	0,96	neutral	-1,41	0	0,39	0,5	neutral	0,38	neutral	0,19	neutral	0,29	neutral	0,34	3	neutral	0,01	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,03	high_impact	1,87	low_impact	-1,77	0,25	0,8	1,73	8,56	N	0,34	N	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9185	9185	T	G	MI.1402	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	659	220	L	R	cTc/cGc	0,82	0,48	0	probably_damaging	1	deleterious	0	neutral	4,09	deleterious	-3,54	deleterious	-5,32	high_impact	4,3	damaging	0,15	neutral	0,34	deleterious	4,32	24	0,19	0,65	NA	NA	disease	0,78	disease	0,77	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	high_impact	2,59	0,54	0,9	50	8,8	P	0,95	P	0,99	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5067	5067	A	G	MI.14020	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	598	200	M	V	Ata/Gta	-6,65	0	0	benign	0	neutral	0,31	neutral	4,72	neutral	1,19	neutral	-1,38	low_impact	1,11	neutral	0,93	neutral	0,77	deleterious	0,7	8,81	0,31	0,45	neutral	0,47	disease	0,63	disease	0,67	disease	0,7	4	neutral	0,69	deleterious	0,66	neutral	-6	neutral	0,21	medium_impact	1,95	medium_impact	0,02	medium_impact	-0,21	0,28	0,8	1,73	8,56	N	0,32	N	0,31	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5068	5068	T	C	MI.14021	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	599	200	M	T	aTa/aCa	-0,66	0	0	benign	0	neutral	0,46	neutral	4,66	neutral	0,3	deleterious	-3,42	low_impact	0,88	neutral	0,96	neutral	0,85	deleterious	0,02	2,74	0,18	0,45	neutral	0,4	disease	0,63	disease	0,58	disease	0,61	2	neutral	0,53	deleterious	0,73	neutral	-6	neutral	0,24	medium_impact	1,95	medium_impact	0,17	medium_impact	-0,4	0,11	0,8	1,73	8,56	N	0,3	N	0,02	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5068	5068	T	A	MI.14022	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	599	200	M	K	aTa/aAa	-0,66	0	0	benign	0,12	neutral	0,09	neutral	4,61	neutral	-1,04	deleterious	-4,32	medium_impact	2,7	neutral	0,84	neutral	0,41	deleterious	2,23	17,68	0,04	0,35	disease	0,79	disease	0,8	disease	0,74	disease	0,71	4	neutral	0,9	deleterious	0,49	neutral	-3	neutral	0,42	medium_impact	-0,01	medium_impact	-0,35	medium_impact	1,13	0,13	0,8	1,73	8,56	N	0,34	N	0,81	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5069	5069	A	C	MI.14023	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	600	200	M	I	atA/atC	3,02	0,15	0	benign	0	neutral	0,34	neutral	4,72	neutral	1,15	neutral	-0,92	neutral_impact	0,38	neutral	0,9	neutral	0,98	deleterious	-0,02	2,4	0,3	0,45	neutral	0,41	neutral	0,43	neutral	0,35	neutral	0,42	2	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,2	medium_impact	1,95	medium_impact	0,05	medium_impact	-0,83	0,23	0,8	1,73	8,56	N	0,41	N	0,06	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5069	5069	A	T	MI.14024	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	600	200	M	I	atA/atT	3,02	0,15	0	benign	0	neutral	0,34	neutral	4,72	neutral	1,15	neutral	-0,92	neutral_impact	0,38	neutral	0,9	neutral	0,98	deleterious	0,01	2,7	0,3	0,45	neutral	0,41	neutral	0,43	neutral	0,35	neutral	0,42	2	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,2	medium_impact	1,95	medium_impact	0,05	medium_impact	-0,83	0,23	0,8	1,73	8,56	N	0,41	N	0,06	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5070	5070	A	G	MI.14025	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	601	201	T	A	Acc/Gcc	-11,94	0	0	benign	0,11	neutral	0,51	neutral	5,03	neutral	2,49	deleterious	-2,52	neutral_impact	0,75	neutral	0,88	neutral	0,94	deleterious	0,45	7,05	0,28	0,45	disease	0,55	neutral	0,25	neutral	0,44	disease	0,54	1	neutral	0,41	deleterious	0,7	neutral	-6	neutral	0,22	medium_impact	0,03	medium_impact	0,22	medium_impact	-0,51	0,35	0,8	0,86	7,69	N	0,42	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5070	5070	A	C	MI.14026	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	601	201	T	P	Acc/Ccc	-11,94	0	0	probably_damaging	0,95	neutral	0,2	neutral	4,56	neutral	-2,46	deleterious	-3,76	medium_impact	2,33	neutral	0,79	neutral	0,34	deleterious	3,26	22,8	0,06	0,35	disease	0,67	disease	0,8	disease	0,72	disease	0,68	4	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,8	low_impact	-1,97	medium_impact	-0,13	medium_impact	0,82	0,34	0,8	0,86	7,69	N	0,26	N	0,98	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5070	5070	A	T	MI.14027	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	601	201	T	S	Acc/Tcc	-11,94	0	0	possibly_damaging	0,72	neutral	0,42	neutral	4,71	neutral	0,81	neutral	-1,95	neutral_impact	0,74	neutral	0,87	neutral	0,91	deleterious	0,42	6,82	0,33	0,5	disease	0,62	disease	0,51	neutral	0,38	neutral	0,25	5	neutral	0,73	neutral	0,35	neutral	-3	deleterious	0,68	low_impact	-1,17	medium_impact	0,13	medium_impact	-0,52	0,65	0,8	0,86	7,69	N	0,34	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5071	5071	C	T	MI.14028	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	602	201	T	I	aCc/aTc	0,26	0	0	probably_damaging	0,91	neutral	0,41	neutral	4,6	neutral	-0,92	deleterious	-2,86	medium_impact	2,58	neutral	0,88	neutral	0,57	deleterious	3,5	23,1	0,17	0,45	disease	0,76	disease	0,74	disease	0,59	disease	0,64	3	neutral	0,91	neutral	0,25	deleterious	1	deleterious	0,75	low_impact	-1,72	medium_impact	0,12	medium_impact	1,03	0,69	0,85	0,86	7,69	N	0,33	N	0,8	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5071	5071	C	A	MI.14029	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	602	201	T	N	aCc/aAc	0,26	0	0	probably_damaging	0,95	neutral	0,31	neutral	4,58	neutral	-1,58	deleterious	-3,12	medium_impact	3,13	neutral	0,85	neutral	0,49	deleterious	3,52	23,1	0,25	0,45	disease	0,68	disease	0,68	disease	0,62	disease	0,64	3	neutral	0,96	neutral	0,18	deleterious	1	deleterious	0,75	low_impact	-1,97	medium_impact	0,02	medium_impact	1,49	0,62	0,8	0,86	7,69	N	0,33	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9185	9185	T	A	MI.1403	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	659	220	L	H	cTc/cAc	0,82	0,48	0	probably_damaging	1	deleterious	0	neutral	4,08	deleterious	-4,12	deleterious	-6,2	high_impact	4,3	damaging	0,38	neutral	0,38	deleterious	4,22	23,9	0,22	0,65	NA	NA	disease	0,7	disease	0,73	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,59	0,58	0,9	50	8,8	P	0,66	P	0,97	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5071	5071	C	G	MI.14030	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	602	201	T	S	aCc/aGc	0,26	0	0	possibly_damaging	0,72	neutral	0,42	neutral	4,71	neutral	0,81	neutral	-1,95	neutral_impact	0,74	neutral	0,87	neutral	0,91	deleterious	0,6	8,13	0,33	0,5	disease	0,62	disease	0,51	neutral	0,38	neutral	0,25	5	neutral	0,73	neutral	0,35	neutral	-3	deleterious	0,68	low_impact	-1,17	medium_impact	0,13	medium_impact	-0,52	0,65	0,8	0,86	7,69	N	0,35	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5073	5073	A	C	MI.14031	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	604	202	I	L	Att/Ctt	-4,58	0	0	benign	0,27	neutral	1	neutral	4,64	neutral	0,06	neutral	0,2	neutral_impact	-0,32	neutral	0,87	neutral	0,97	neutral	1,06	11,01	0,23	0,45	neutral	0,39	neutral	0,11	neutral	0,28	neutral	0,22	6	neutral	0,27	deleterious	0,87	neutral	-6	neutral	0,28	medium_impact	-0,4	high_impact	1,87	low_impact	-1,41	0,57	0,8	0,29	6,64	N	0,32	N	0,2	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5073	5073	A	G	MI.14032	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	604	202	I	V	Att/Gtt	-4,58	0	0	benign	0,03	neutral	0,11	neutral	4,53	neutral	-0,6	neutral	-0,46	low_impact	0,82	neutral	0,96	neutral	0,94	deleterious	1,91	15,63	0,38	0,5	neutral	0,5	neutral	0,25	neutral	0,4	neutral	0,3	4	neutral	0,89	deleterious	0,54	neutral	-6	neutral	0,15	medium_impact	0,59	medium_impact	-0,3	medium_impact	-0,45	0,47	0,8	0,29	6,64	N	0,48	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5073	5073	A	T	MI.14033	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	604	202	I	F	Att/Ttt	-4,58	0	0	possibly_damaging	0,76	neutral	0,38	neutral	4,55	neutral	-1,91	neutral	-2,25	neutral_impact	0,58	neutral	0,91	neutral	0,82	deleterious	4,02	23,6	0,18	0,45	disease	0,75	disease	0,57	disease	0,53	neutral	0,27	5	neutral	0,77	neutral	0,31	neutral	-3	deleterious	0,71	low_impact	-1,26	medium_impact	0,09	medium_impact	-0,66	0,54	0,8	0,29	6,64	N	0,39	N	0,34	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5074	5074	T	A	MI.14034	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	605	202	I	N	aTt/aAt	-11,02	0	0	possibly_damaging	0,76	neutral	0,15	neutral	4,42	deleterious	-4,09	deleterious	-4,42	medium_impact	2,8	neutral	0,88	neutral	0,42	deleterious	4,4	24,1	0,07	0,35	disease	0,89	disease	0,68	disease	0,64	disease	0,68	4	neutral	0,89	neutral	0,2	NA	0	deleterious	0,75	low_impact	-1,26	medium_impact	-0,21	medium_impact	1,21	0,31	0,8	0,29	6,64	N	0,41	N	0,78	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5074	5074	T	C	MI.14035	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	605	202	I	T	aTt/aCt	-11,02	0	0	benign	0,03	neutral	0,19	neutral	4,46	neutral	-2,33	neutral	-2,36	neutral_impact	0,64	neutral	0,97	neutral	0,96	deleterious	2,16	17,25	0,08	0,35	disease	0,64	neutral	0,38	neutral	0,42	disease	0,61	2	neutral	0,8	deleterious	0,58	neutral	-6	neutral	0,2	medium_impact	0,59	medium_impact	-0,14	medium_impact	-0,61	0,25	0,8	0,29	6,64	N	0,46	N	0,41	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5074	5074	T	G	MI.14036	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	605	202	I	S	aTt/aGt	-11,02	0	0	benign	0,37	neutral	0,31	neutral	4,47	neutral	-2,89	deleterious	-3,44	low_impact	1,64	neutral	0,87	neutral	0,58	deleterious	4,3	24	0,03	0,35	disease	0,53	disease	0,64	disease	0,62	disease	0,69	4	neutral	0,63	deleterious	0,47	neutral	-6	deleterious	0,53	medium_impact	-0,59	medium_impact	0,02	medium_impact	0,24	0,24	0,8	0,29	6,64	N	0,34	N	0,66	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5075	5075	T	A	MI.14037	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	606	202	I	M	atT/atA	1,41	0	0	possibly_damaging	0,86	neutral	0,13	neutral	4,55	neutral	-1,52	neutral	-0,29	neutral_impact	0,67	neutral	0,87	neutral	0,94	deleterious	2,48	19,32	0,25	0,45	disease	0,62	neutral	0,24	neutral	0,34	disease	0,55	1	neutral	0,94	neutral	0,14	neutral	-3	deleterious	0,66	low_impact	-1,52	medium_impact	-0,25	medium_impact	-0,58	0,59	0,8	0,29	6,64	N	0,52	P	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5075	5075	T	G	MI.14038	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	606	202	I	M	atT/atG	1,41	0	0	possibly_damaging	0,86	neutral	0,13	neutral	4,55	neutral	-1,52	neutral	-0,29	neutral_impact	0,67	neutral	0,87	neutral	0,94	deleterious	2,13	17,03	0,25	0,45	disease	0,62	neutral	0,24	neutral	0,34	disease	0,55	1	neutral	0,94	neutral	0,14	neutral	-3	deleterious	0,66	low_impact	-1,52	medium_impact	-0,25	medium_impact	-0,58	0,59	0,8	0,29	6,64	N	0,52	P	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5076	5076	C	A	MI.14039	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	607	203	L	I	Ctt/Att	-11,71	0	0	possibly_damaging	0,56	neutral	0,48	neutral	4,69	neutral	0,24	neutral	-1,72	low_impact	1,36	neutral	0,9	neutral	0,69	deleterious	2,29	18,1	0,36	0,5	disease	0,64	neutral	0,28	neutral	0,38	disease	0,53	1	neutral	0,56	neutral	0,46	neutral	-3	deleterious	0,56	medium_impact	-0,89	medium_impact	0,19	medium_impact	0	0,57	0,8	NA	NA	N	0,36	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9187	9187	T	A	MI.1404	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	661	221	Y	N	Tac/Aac	-14,45	0	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-9,09	deleterious	-7,94	high_impact	4,55	damaging	0,43	neutral	0,46	deleterious	4,09	23,7	0,2	0,65	NA	NA	disease	0,77	disease	0,77	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,6	low_impact	-1,4	high_impact	2,8	0,23	0,9	48,67	8,74	P	0,52	P	1	disease_causing	0,84	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5076	5076	C	T	MI.14040	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	607	203	L	F	Ctt/Ttt	-11,71	0	0	benign	0,04	neutral	0,33	neutral	4,55	neutral	-0,6	deleterious	-2,86	low_impact	1,21	neutral	0,88	neutral	0,73	neutral	0,91	10,14	0,29	0,45	disease	0,78	neutral	0,47	neutral	0,4	neutral	0,49	0	neutral	0,65	deleterious	0,65	neutral	-6	neutral	0,26	medium_impact	0,47	medium_impact	0,04	medium_impact	-0,13	0,57	0,8	NA	NA	N	0,39	N	0,18	polymorphism	1	0,06	rs386828960	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5076	5076	C	G	MI.14041	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	607	203	L	V	Ctt/Gtt	-11,71	0	0	possibly_damaging	0,56	neutral	0,17	neutral	4,49	neutral	-1,21	deleterious	-2,67	medium_impact	1,94	neutral	0,94	neutral	0,58	neutral	1,64	14,07	0,36	0,5	disease	0,57	neutral	0,42	disease	0,54	disease	0,6	2	neutral	0,82	neutral	0,31	NA	0	deleterious	0,6	medium_impact	-0,89	medium_impact	-0,17	medium_impact	0,49	0,68	0,85	NA	NA	N	0,44	N	0,41	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5077	5077	T	C	MI.14042	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	608	203	L	P	cTt/cCt	-1,81	0	0	probably_damaging	0,95	neutral	0,05	neutral	4,37	deleterious	-4,34	deleterious	-6,39	medium_impact	3,29	neutral	0,85	neutral	0,37	deleterious	3,72	23,3	0,02	0,35	neutral	0,38	disease	0,72	disease	0,74	disease	0,68	4	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,78	low_impact	-1,97	medium_impact	-0,5	medium_impact	1,63	0,22	0,8	NA	NA	N	0,38	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5077	5077	T	A	MI.14043	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	608	203	L	H	cTt/cAt	-1,81	0	0	probably_damaging	0,97	neutral	0,11	neutral	4,37	deleterious	-4,29	deleterious	-6,1	medium_impact	3,29	neutral	0,88	neutral	0,36	deleterious	3,94	23,5	0,04	0,35	disease	0,86	disease	0,68	disease	0,7	disease	0,67	3	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,81	low_impact	-2,18	medium_impact	-0,3	medium_impact	1,63	0,21	0,8	NA	NA	N	0,41	N	0,86	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5077	5077	T	G	MI.14044	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	608	203	L	R	cTt/cGt	-1,81	0	0	probably_damaging	0,93	deleterious	0,04	neutral	4,38	deleterious	-3,75	deleterious	-5,43	high_impact	3,64	neutral	0,85	neutral	0,37	deleterious	3,93	23,5	0,02	0,35	disease	0,79	disease	0,8	disease	0,73	disease	0,68	4	deleterious	0,99	neutral	0,06	deleterious	6	deleterious	0,84	low_impact	-1,83	medium_impact	-0,56	medium_impact	1,92	0,22	0,8	NA	NA	N	0,37	N	0,97	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5079	5079	A	T	MI.14045	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	610	204	N	Y	Aat/Tat	-5,5	0	0	benign	0,01	neutral	1	neutral	4,72	neutral	1,34	deleterious	-6,25	neutral_impact	0,64	neutral	0,91	neutral	0,59	deleterious	3,66	23,2	0,13	0,4	disease	0,77	disease	0,77	disease	0,65	disease	0,55	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,26	medium_impact	1,03	high_impact	1,87	medium_impact	-0,61	0,28	0,8	NA	NA	N	0,23	N	0,62	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5079	5079	A	C	MI.14046	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	610	204	N	H	Aat/Cat	-5,5	0	0	possibly_damaging	0,6	neutral	0,44	neutral	4,81	neutral	0,77	deleterious	-4,04	medium_impact	3,41	neutral	0,88	neutral	0,3	deleterious	3,09	22,5	0,3	0,45	disease	0,85	disease	0,72	disease	0,73	disease	0,66	3	neutral	0,61	neutral	0,42	NA	0	deleterious	0,69	medium_impact	-0,96	medium_impact	0,15	medium_impact	1,73	0,26	0,8	NA	NA	N	0,34	N	0,62	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5079	5079	A	G	MI.14047	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	610	204	N	D	Aat/Gat	-5,5	0	0	benign	0,31	neutral	0,17	neutral	4,62	neutral	-0,94	deleterious	-4,39	medium_impact	3,41	neutral	0,86	neutral	0,46	deleterious	3,84	23,4	0,46	0,55	disease	0,85	disease	0,65	disease	0,7	disease	0,67	3	neutral	0,8	neutral	0,43	neutral	-3	deleterious	0,51	medium_impact	-0,48	medium_impact	-0,17	medium_impact	1,73	0,35	0,8	NA	NA	N	0,35	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5080	5080	A	G	MI.14048	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	611	204	N	S	aAt/aGt	2,56	0,11	0	benign	0,02	neutral	0,47	neutral	4,65	neutral	0,12	deleterious	-4,25	medium_impact	2,31	neutral	0,91	neutral	0,65	deleterious	3,12	22,5	0,44	0,55	neutral	0,41	disease	0,63	neutral	0,49	neutral	0,16	7	neutral	0,51	deleterious	0,73	neutral	-3	neutral	0,2	medium_impact	0,75	medium_impact	0,18	medium_impact	0,8	0,46	0,8	NA	NA	N	0,4	N	0,84	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5080	5080	A	T	MI.14049	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	611	204	N	I	aAt/aTt	2,56	0,11	0	benign	0,35	neutral	0,49	neutral	4,76	neutral	-2,14	deleterious	-7,7	medium_impact	3,41	neutral	0,89	neutral	0,56	deleterious	3,89	23,5	0,14	0,4	neutral	0,36	disease	0,82	disease	0,62	disease	0,67	3	neutral	0,43	deleterious	0,57	neutral	-3	deleterious	0,54	medium_impact	-0,55	medium_impact	0,2	medium_impact	1,73	0,24	0,8	NA	NA	N	0,45	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9187	9187	T	C	MI.1405	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	661	221	Y	H	Tac/Cac	-14,45	0	0	probably_damaging	1	deleterious	0	neutral	2,64	deleterious	-7,7	deleterious	-4,41	high_impact	4,55	damaging	0,53	neutral	0,41	deleterious	3,63	23,2	0,23	0,65	NA	NA	disease	0,73	disease	0,86	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,8	0,27	0,9	48,67	8,74	N	0,52	P	0,99	polymorphism	0,69	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5080	5080	A	C	MI.14050	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	611	204	N	T	aAt/aCt	2,56	0,11	0	benign	0,01	neutral	0,5	neutral	4,69	neutral	-0,74	deleterious	-5,11	low_impact	0,94	neutral	0,84	neutral	0,62	deleterious	3,36	22,9	0,23	0,45	disease	0,52	neutral	0,39	neutral	0,44	neutral	0,33	3	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,18	medium_impact	1,03	medium_impact	0,21	medium_impact	-0,35	0,39	0,8	NA	NA	N	0,34	N	0,82	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5081	5081	T	G	MI.14051	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	612	204	N	K	aaT/aaG	1,87	0,1	0,01	benign	0,25	neutral	0,29	neutral	4,64	neutral	-0,31	deleterious	-5,18	medium_impact	3,41	neutral	0,87	neutral	0,38	deleterious	4,06	23,7	0,29	0,45	disease	0,76	disease	0,79	disease	0,71	disease	0,68	4	neutral	0,65	deleterious	0,52	neutral	-3	deleterious	0,55	medium_impact	-0,36	medium_impact	-0,01	medium_impact	1,73	0,48	0,8	NA	NA	N	0,41	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5081	5081	T	A	MI.14052	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	612	204	N	K	aaT/aaA	1,87	0,1	0,01	benign	0,25	neutral	0,29	neutral	4,64	neutral	-0,31	deleterious	-5,18	medium_impact	3,41	neutral	0,87	neutral	0,38	deleterious	4,38	24,1	0,29	0,45	disease	0,76	disease	0,79	disease	0,71	disease	0,68	4	neutral	0,65	deleterious	0,52	neutral	-3	deleterious	0,55	medium_impact	-0,36	medium_impact	-0,01	medium_impact	1,73	0,48	0,8	NA	NA	N	0,41	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5082	5082	T	A	MI.14053	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	613	205	L	M	Tta/Ata	-1,35	0	0,01	probably_damaging	1	neutral	0,32	neutral	4,43	neutral	-1,13	neutral	-1,81	low_impact	1,77	neutral	0,96	neutral	0,71	deleterious	3,79	23,4	0,3	0,45	disease	0,76	neutral	0,36	disease	0,52	disease	0,65	3	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	0,03	medium_impact	0,35	0,61	0,8	NA	NA	N	0,46	N	0,64	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5082	5082	T	G	MI.14054	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	613	205	L	V	Tta/Gta	-1,35	0	0,01	probably_damaging	1	neutral	0,34	neutral	4,34	neutral	-1,9	deleterious	-2,83	medium_impact	2,58	neutral	0,89	neutral	0,52	deleterious	3,45	23	0,23	0,45	neutral	0,5	neutral	0,42	disease	0,62	neutral	0,46	1	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0,05	medium_impact	1,03	0,59	0,8	NA	NA	N	0,42	N	0,51	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5083	5083	T	G	MI.14055	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	614	205	L	W	tTa/tGa	-1,58	0	0	probably_damaging	1	neutral	0,09	neutral	4,22	deleterious	-5,7	deleterious	-5,67	medium_impact	2,65	neutral	0,86	neutral	0,42	deleterious	3,73	23,3	0,05	0,35	disease	0,75	disease	0,62	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,35	medium_impact	1,09	0,25	0,8	NA	NA	N	0,37	N	0,88	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5083	5083	T	C	MI.14056	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	614	205	L	S	tTa/tCa	-1,58	0	0	probably_damaging	1	neutral	0,5	neutral	4,26	deleterious	-3,49	deleterious	-5,67	high_impact	3,62	neutral	0,84	neutral	0,55	deleterious	3,75	23,3	0,06	0,35	disease	0,86	disease	0,6	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0,21	medium_impact	1,9	0,26	0,8	NA	NA	N	0,29	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5084	5084	A	C	MI.14057	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	615	205	L	F	ttA/ttC	3,71	0,33	0,01	probably_damaging	1	neutral	0,68	neutral	4,33	neutral	-2,03	deleterious	-3,78	low_impact	0,84	neutral	0,89	neutral	0,66	deleterious	3,43	23	0,26	0,45	neutral	0,37	neutral	0,07	neutral	0,42	neutral	0,22	6	deleterious	1	neutral	0,34	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,39	medium_impact	-0,44	0,59	0,8	NA	NA	N	0,42	N	0,66	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5084	5084	A	T	MI.14058	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	615	205	L	F	ttA/ttT	3,71	0,33	0,01	probably_damaging	1	neutral	0,68	neutral	4,33	neutral	-2,03	deleterious	-3,78	low_impact	0,84	neutral	0,89	neutral	0,66	deleterious	3,55	23,1	0,26	0,45	neutral	0,37	neutral	0,07	neutral	0,42	neutral	0,22	6	deleterious	1	neutral	0,34	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,39	medium_impact	-0,44	0,59	0,8	NA	NA	N	0,42	N	0,66	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5085	5085	A	G	MI.14059	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	616	206	T	A	Act/Gct	-2,04	0	0	benign	0,01	neutral	0,25	neutral	4,66	neutral	0,35	neutral	-0,89	neutral_impact	0,64	neutral	0,92	neutral	0,93	deleterious	0,43	6,86	0,25	0,45	neutral	0,4	neutral	0,13	neutral	0,49	neutral	0,31	4	neutral	0,75	deleterious	0,62	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	-0,06	medium_impact	-0,61	0,37	0,8	2,02	8,05	N	0,49	N	0,27	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9187	9187	T	G	MI.1406	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	661	221	Y	D	Tac/Gac	-14,45	0	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-10,32	deleterious	-8,82	high_impact	4,55	damaging	0,55	neutral	0,42	deleterious	4,01	23,6	0,14	0,65	NA	NA	disease	0,8	disease	0,85	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,8	0,26	0,9	48,67	8,74	N	0,47	N	1	disease_causing	0,79	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5085	5085	A	T	MI.14060	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	616	206	T	S	Act/Tct	-2,04	0	0	benign	0,14	neutral	0,41	neutral	4,61	neutral	-0,78	neutral	-1,43	neutral_impact	0,44	neutral	0,89	neutral	0,93	deleterious	0,45	7,01	0,4	0,5	disease	0,7	neutral	0,2	neutral	0,38	disease	0,51	0	neutral	0,52	deleterious	0,64	neutral	-6	neutral	0,3	medium_impact	-0,08	medium_impact	0,12	medium_impact	-0,77	0,45	0,8	2,02	8,05	N	0,47	N	0,33	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5085	5085	A	C	MI.14061	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	616	206	T	P	Act/Cct	-2,04	0	0	possibly_damaging	0,55	neutral	0,13	neutral	4,58	neutral	-2,32	deleterious	-2,59	medium_impact	2,34	neutral	0,8	neutral	0,33	deleterious	3,32	22,9	0,06	0,35	disease	0,67	disease	0,66	disease	0,65	disease	0,7	4	neutral	0,86	neutral	0,29	NA	0	deleterious	0,66	medium_impact	-0,88	medium_impact	-0,25	medium_impact	0,83	0,35	0,8	2,02	8,05	N	0,3	N	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5086	5086	C	G	MI.14062	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	617	206	T	S	aCt/aGt	-6,19	0	0	benign	0,14	neutral	0,41	neutral	4,61	neutral	-0,78	neutral	-1,43	neutral_impact	0,44	neutral	0,89	neutral	0,93	deleterious	0,59	8,08	0,4	0,5	disease	0,7	neutral	0,2	neutral	0,38	disease	0,51	0	neutral	0,52	deleterious	0,64	neutral	-6	neutral	0,3	medium_impact	-0,08	medium_impact	0,12	medium_impact	-0,77	0,45	0,8	2,02	8,05	N	0,42	N	0,33	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5086	5086	C	A	MI.14063	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	617	206	T	N	aCt/aAt	-6,19	0	0	possibly_damaging	0,55	neutral	0,14	neutral	4,59	neutral	-2,03	neutral	-2,41	medium_impact	2,34	neutral	0,83	neutral	0,51	deleterious	3,54	23,1	0,22	0,45	disease	0,82	neutral	0,38	disease	0,53	disease	0,66	3	neutral	0,85	neutral	0,3	NA	0	deleterious	0,65	medium_impact	-0,88	medium_impact	-0,23	medium_impact	0,83	0,51	0,8	2,02	8,05	N	0,38	N	0,61	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5086	5086	C	T	MI.14064	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	617	206	T	I	aCt/aTt	-6,19	0	0	benign	0,01	neutral	0,62	neutral	4,95	neutral	2,48	neutral	1,53	neutral_impact	-0,72	neutral	0,96	neutral	0,98	neutral	-0,54	0,18	0,1	0,4	disease	0,52	neutral	0,2	neutral	0,39	neutral	0,27	5	neutral	0,36	deleterious	0,81	neutral	-6	neutral	0,14	medium_impact	1,03	medium_impact	0,33	low_impact	-1,75	0,59	0,8	2,02	8,05	N	0,31	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5088	5088	A	T	MI.14065	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	619	207	I	F	Att/Ttt	-7,57	0	0	possibly_damaging	0,61	neutral	0,58	neutral	4,51	neutral	-0,08	deleterious	-3,17	low_impact	1,6	neutral	0,9	neutral	0,46	deleterious	3,8	23,4	0,15	0,4	disease	0,52	disease	0,72	disease	0,62	disease	0,67	3	neutral	0,55	deleterious	0,49	neutral	-3	deleterious	0,62	medium_impact	-0,98	medium_impact	0,29	medium_impact	0,2	0,49	0,8	NA	NA	N	0,25	N	0,74	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5088	5088	A	G	MI.14066	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	619	207	I	V	Att/Gtt	-7,57	0	0	benign	0,01	neutral	0,44	neutral	4,58	neutral	0,45	neutral	-0,73	low_impact	1,44	neutral	0,97	neutral	0,93	neutral	1,09	11,17	0,32	0,5	neutral	0,46	neutral	0,24	neutral	0,4	neutral	0,44	1	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,14	medium_impact	1,03	medium_impact	0,15	medium_impact	0,07	0,46	0,8	NA	NA	N	0,39	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5088	5088	A	C	MI.14067	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	619	207	I	L	Att/Ctt	-7,57	0	0	benign	0,08	neutral	1	neutral	4,62	neutral	0,01	neutral	-1,05	low_impact	1,07	neutral	0,87	neutral	0,96	deleterious	0,54	7,73	0,19	0,45	disease	0,65	neutral	0,19	neutral	0,33	neutral	0,49	0	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,21	medium_impact	0,17	high_impact	1,87	medium_impact	-0,24	0,46	0,8	NA	NA	N	0,3	N	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5089	5089	T	C	MI.14068	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	620	207	I	T	aTt/aCt	0,49	0	0	benign	0,02	neutral	0,46	neutral	4,72	neutral	-0,26	deleterious	-3,68	low_impact	1,41	neutral	0,97	neutral	0,79	deleterious	0,42	6,76	0,09	0,35	disease	0,65	neutral	0,4	neutral	0,39	disease	0,62	2	neutral	0,52	deleterious	0,72	neutral	-6	neutral	0,19	medium_impact	0,75	medium_impact	0,17	medium_impact	0,04	0,34	0,8	NA	NA	N	0,37	N	0,67	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5089	5089	T	A	MI.14069	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	620	207	I	N	aTt/aAt	0,49	0	0	possibly_damaging	0,75	neutral	0,37	neutral	4,49	neutral	-1,4	deleterious	-5,68	medium_impact	3,23	neutral	0,88	neutral	0,39	deleterious	4,27	24	0,13	0,4	neutral	0,41	disease	0,76	disease	0,6	disease	0,68	4	neutral	0,77	neutral	0,31	NA	0	deleterious	0,63	low_impact	-1,23	medium_impact	0,08	medium_impact	1,57	0,33	0,8	NA	NA	N	0,35	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9188	9188	A	C	MI.1407	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	662	221	Y	S	tAc/tCc	7,53	1	0	probably_damaging	1	neutral	0,08	neutral	2,63	deleterious	-9,01	deleterious	-7,93	high_impact	4,21	damaging	0,47	neutral	0,59	deleterious	4,53	24,3	0,18	0,65	NA	NA	disease	0,77	disease	0,78	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,31	high_impact	2,51	0,26	0,9	48,67	8,74	P	0,52	P	0,99	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5089	5089	T	G	MI.14070	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	620	207	I	S	aTt/aGt	0,49	0	0	benign	0,29	neutral	0,48	neutral	4,66	neutral	-0,61	deleterious	-4,73	medium_impact	2,25	neutral	0,89	neutral	0,46	deleterious	3,75	23,3	0,05	0,35	disease	0,68	disease	0,75	disease	0,58	disease	0,67	3	neutral	0,42	deleterious	0,6	neutral	-3	deleterious	0,55	medium_impact	-0,44	medium_impact	0,19	medium_impact	0,75	0,26	0,8	NA	NA	N	0,34	N	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5090	5090	T	A	MI.14071	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	621	207	I	M	atT/atA	1,41	0	0	benign	0,06	neutral	0,34	neutral	4,53	neutral	-1,47	neutral	-1,75	low_impact	1,81	neutral	0,94	neutral	0,88	deleterious	2,38	18,7	0,28	0,45	disease	0,61	neutral	0,38	neutral	0,38	disease	0,61	2	neutral	0,63	deleterious	0,64	neutral	-6	neutral	0,25	medium_impact	0,3	medium_impact	0,05	medium_impact	0,38	0,51	0,8	NA	NA	N	0,43	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5090	5090	T	G	MI.14072	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	621	207	I	M	atT/atG	1,41	0	0	benign	0,06	neutral	0,34	neutral	4,53	neutral	-1,47	neutral	-1,75	low_impact	1,81	neutral	0,94	neutral	0,88	deleterious	2,16	17,27	0,28	0,45	disease	0,61	neutral	0,38	neutral	0,38	disease	0,61	2	neutral	0,63	deleterious	0,64	neutral	-6	neutral	0,25	medium_impact	0,3	medium_impact	0,05	medium_impact	0,38	0,51	0,8	NA	NA	N	0,43	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5091	5091	T	G	MI.14073	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	622	208	Y	D	Tat/Gat	-16,09	0	0	probably_damaging	1	neutral	0,16	neutral	4,28	deleterious	-5,59	deleterious	-9,53	high_impact	4,11	neutral	0,89	damaging	0,13	deleterious	3,98	23,6	0,04	0,35	disease	0,79	disease	0,86	disease	0,82	disease	0,68	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,19	high_impact	2,32	0,17	0,8	NA	NA	N	0,49	N	0,96	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5091	5091	T	C	MI.14074	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	622	208	Y	H	Tat/Cat	-16,09	0	0	probably_damaging	1	neutral	0,3	neutral	5,04	neutral	1,26	deleterious	-4,77	high_impact	3,56	neutral	0,85	damaging	0,11	deleterious	3,58	23,2	0,11	0,4	disease	0,66	disease	0,82	disease	0,78	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,76	low_impact	-3,54	medium_impact	0	medium_impact	1,85	0,23	0,8	NA	NA	N	0,34	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5091	5091	T	A	MI.14075	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	622	208	Y	N	Tat/Aat	-16,09	0	0	probably_damaging	1	neutral	0,25	neutral	4,29	deleterious	-4,97	deleterious	-8,58	high_impact	3,76	neutral	0,87	damaging	0,14	deleterious	4,04	23,7	0,06	0,35	disease	0,68	disease	0,84	disease	0,76	disease	0,7	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	-0,06	high_impact	2,02	0,2	0,8	NA	NA	N	0,4	N	1	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5092	5092	A	G	MI.14076	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	623	208	Y	C	tAt/tGt	4,63	1	0	probably_damaging	1	neutral	0,09	neutral	4,28	deleterious	-6,39	deleterious	-8,58	high_impact	4,11	neutral	0,89	damaging	0,11	deleterious	3,57	23,1	0,06	0,35	disease	0,9	disease	0,86	disease	0,81	disease	0,64	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,35	high_impact	2,32	0,15	0,8	NA	NA	P	0,66	P	1	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5092	5092	A	C	MI.14077	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	623	208	Y	S	tAt/tCt	4,63	1	0	probably_damaging	1	neutral	0,33	neutral	4,29	deleterious	-4,51	deleterious	-8,58	high_impact	4,11	neutral	0,85	damaging	0,16	deleterious	3,75	23,3	0,07	0,35	neutral	0,48	disease	0,84	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	0,04	high_impact	2,32	0,25	0,8	NA	NA	P	0,59	P	0,96	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5092	5092	A	T	MI.14078	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	623	208	Y	F	tAt/tTt	4,63	1	0	probably_damaging	1	neutral	0,54	neutral	4,44	neutral	-1,29	deleterious	-3,82	high_impact	3,76	neutral	0,83	damaging	0,11	deleterious	3,42	23	0,14	0,4	disease	0,81	disease	0,82	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,25	high_impact	2,02	0,42	0,8	NA	NA	P	0,53	P	0,8	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5094	5094	A	C	MI.14079	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	625	209	I	L	Att/Ctt	-6,19	0	0	benign	0,09	neutral	0,47	neutral	4,65	neutral	0,31	neutral	-1,38	low_impact	1,17	neutral	0,84	neutral	0,88	deleterious	2,45	19,14	0,18	0,45	neutral	0,45	neutral	0,4	neutral	0,29	neutral	0,47	1	neutral	0,46	deleterious	0,69	neutral	-6	neutral	0,19	medium_impact	0,12	medium_impact	0,18	medium_impact	-0,16	0,59	0,8	NA	NA	N	0,35	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9188	9188	A	T	MI.1408	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	662	221	Y	F	tAc/tTc	7,53	1	0	probably_damaging	0,99	deleterious	0,02	neutral	2,72	deleterious	-3,69	deleterious	-3,53	medium_impact	3,13	damaging	0,51	neutral	0,43	deleterious	4,3	24	0,2	0,65	NA	NA	disease	0,69	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,85	low_impact	-2,65	medium_impact	-0,66	medium_impact	1,59	0,4	0,9	48,67	8,74	P	0,53	P	0,81	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5094	5094	A	T	MI.14080	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	625	209	I	F	Att/Ttt	-6,19	0	0	probably_damaging	0,93	neutral	0,52	neutral	4,55	neutral	-2,49	deleterious	-3,49	low_impact	1,47	neutral	0,9	neutral	0,66	deleterious	3,51	23,1	0,16	0,45	disease	0,58	disease	0,71	neutral	0,38	neutral	0,19	6	neutral	0,92	neutral	0,3	neutral	-2	deleterious	0,71	low_impact	-1,83	medium_impact	0,23	medium_impact	0,09	0,5	0,8	NA	NA	N	0,3	N	0,48	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5094	5094	A	G	MI.14081	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	625	209	I	V	Att/Gtt	-6,19	0	0	possibly_damaging	0,67	neutral	0,37	neutral	4,64	neutral	-0,3	neutral	-0,89	low_impact	1,66	neutral	0,94	neutral	0,84	deleterious	1,84	15,21	0,32	0,5	neutral	0,47	neutral	0,28	neutral	0,37	neutral	0,44	1	neutral	0,71	neutral	0,35	neutral	-3	deleterious	0,56	low_impact	-1,08	medium_impact	0,08	medium_impact	0,25	0,45	0,8	NA	NA	N	0,45	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5095	5095	T	C	MI.14082	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	626	209	I	T	aTt/aCt	-2,04	0	0	probably_damaging	0,94	neutral	0,37	neutral	4,56	neutral	-1,66	deleterious	-4,42	low_impact	1,38	neutral	0,94	neutral	0,6	deleterious	3,39	23	0,11	0,4	neutral	0,37	neutral	0,39	disease	0,54	neutral	0,47	1	neutral	0,94	neutral	0,22	neutral	-2	deleterious	0,65	low_impact	-1,89	medium_impact	0,08	medium_impact	0,02	0,27	0,8	NA	NA	N	0,39	N	0,68	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5095	5095	T	A	MI.14083	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	626	209	I	N	aTt/aAt	-2,04	0	0	probably_damaging	0,98	neutral	0,2	neutral	4,56	deleterious	-3,69	deleterious	-6,3	medium_impact	3,4	neutral	0,89	neutral	0,4	deleterious	4,4	24,1	0,08	0,35	disease	0,76	disease	0,77	disease	0,56	disease	0,67	3	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,76	low_impact	-2,34	medium_impact	-0,13	medium_impact	1,72	0,32	0,8	NA	NA	N	0,43	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5095	5095	T	G	MI.14084	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	626	209	I	S	aTt/aGt	-2,04	0	0	probably_damaging	0,97	neutral	0,4	neutral	4,58	neutral	-1,38	deleterious	-5,35	low_impact	0,98	neutral	0,82	neutral	0,53	deleterious	4,3	24	0,06	0,35	disease	0,58	disease	0,65	disease	0,54	neutral	0,38	2	neutral	0,97	neutral	0,22	neutral	-2	deleterious	0,71	low_impact	-2,18	medium_impact	0,11	medium_impact	-0,32	0,28	0,8	NA	NA	N	0,26	N	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5096	5096	T	A	MI.14085	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	627	209	I	M	atT/atA	2,1	0,02	0	probably_damaging	0,96	neutral	0,28	neutral	4,57	neutral	-1,2	neutral	-2,26	low_impact	1,13	neutral	0,89	neutral	0,8	deleterious	3,65	23,2	0,22	0,45	disease	0,57	disease	0,5	neutral	0,32	neutral	0,26	5	neutral	0,97	neutral	0,16	neutral	-2	deleterious	0,68	low_impact	-2,06	medium_impact	-0,02	medium_impact	-0,19	0,51	0,8	NA	NA	N	0,42	N	0,64	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5096	5096	T	G	MI.14086	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	627	209	I	M	atT/atG	2,1	0,02	0	probably_damaging	0,96	neutral	0,28	neutral	4,57	neutral	-1,2	neutral	-2,26	low_impact	1,13	neutral	0,89	neutral	0,8	deleterious	3,33	22,9	0,22	0,45	disease	0,57	disease	0,5	neutral	0,32	neutral	0,26	5	neutral	0,97	neutral	0,16	neutral	-2	deleterious	0,68	low_impact	-2,06	medium_impact	-0,02	medium_impact	-0,19	0,51	0,8	NA	NA	N	0,42	N	0,64	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5097	5097	A	G	MI.14087	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	628	210	I	V	Atc/Gtc	-10,79	0	0	benign	0	neutral	0,45	neutral	4,7	neutral	-0,32	neutral	-0,44	low_impact	1,22	neutral	0,96	neutral	0,92	neutral	-0,09	1,83	0,28	0,45	disease	0,69	neutral	0,19	neutral	0,37	neutral	0,5	0	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,16	medium_impact	-0,12	0,53	0,8	NA	NA	N	0,39	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5097	5097	A	C	MI.14088	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	628	210	I	L	Atc/Ctc	-10,79	0	0	benign	0,01	neutral	0,99	neutral	4,84	neutral	0,62	neutral	0,22	neutral_impact	0,54	neutral	0,87	neutral	0,97	neutral	-0,46	0,28	0,16	0,45	neutral	0,45	neutral	0,17	neutral	0,3	neutral	0,25	5	neutral	0	deleterious	0,99	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	1,32	medium_impact	-0,69	0,52	0,8	NA	NA	N	0,35	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5097	5097	A	T	MI.14089	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	628	210	I	F	Atc/Ttc	-10,79	0	0	benign	0,01	neutral	0,87	neutral	4,89	neutral	-0,11	neutral	-1,92	neutral_impact	0,59	neutral	0,88	neutral	0,96	deleterious	0,83	9,64	0,14	0,4	disease	0,72	disease	0,58	neutral	0,39	neutral	0,25	5	neutral	0,1	deleterious	0,93	neutral	-6	neutral	0,21	medium_impact	1,03	medium_impact	0,67	medium_impact	-0,65	0,54	0,8	NA	NA	N	0,28	N	0,31	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9188	9188	A	G	MI.1409	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	662	221	Y	C	tAc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-10,51	deleterious	-7,96	high_impact	4,55	damaging	0,42	neutral	0,33	deleterious	4,38	24,1	0,23	0,65	NA	NA	disease	0,78	disease	0,83	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,8	0,21	0,9	48,67	8,74	P	0,6	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5098	5098	T	G	MI.14090	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	629	210	I	S	aTc/aGc	-1,35	0	0	benign	0,14	neutral	0,62	neutral	4,61	neutral	-2,55	deleterious	-3,18	low_impact	1,56	neutral	0,86	neutral	0,72	neutral	1,26	12,05	0,05	0,35	disease	0,91	disease	0,65	disease	0,59	disease	0,7	4	neutral	0,27	deleterious	0,74	neutral	-6	neutral	0,36	medium_impact	-0,08	medium_impact	0,33	medium_impact	0,17	0,25	0,8	NA	NA	N	0,21	N	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5098	5098	T	A	MI.14091	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	629	210	I	N	aTc/aAc	-1,35	0	0	benign	0,39	neutral	0,23	neutral	4,55	deleterious	-4,03	deleterious	-4,16	medium_impact	2,19	neutral	0,89	neutral	0,41	deleterious	2,61	20,3	0,1	0,4	disease	0,96	disease	0,71	disease	0,6	disease	0,7	4	neutral	0,73	neutral	0,42	neutral	-3	deleterious	0,64	medium_impact	-0,62	medium_impact	-0,08	medium_impact	0,7	0,27	0,8	NA	NA	N	0,42	N	0,83	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5098	5098	T	C	MI.14092	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	629	210	I	T	aTc/aCc	-1,35	0	0	benign	0,01	neutral	0,57	neutral	4,61	neutral	-2,18	neutral	-2,13	neutral_impact	0,78	neutral	0,93	neutral	0,98	neutral	-0,18	1,21	0,1	0,4	disease	0,73	neutral	0,27	neutral	0,4	disease	0,58	2	neutral	0,41	deleterious	0,78	neutral	-6	neutral	0,16	medium_impact	1,03	medium_impact	0,28	medium_impact	-0,49	0,25	0,8	NA	NA	N	0,33	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5099	5099	C	G	MI.14093	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	630	210	I	M	atC/atG	-0,2	0	0,01	possibly_damaging	0,66	neutral	0,79	neutral	4,6	neutral	-1,94	neutral	-0,15	neutral_impact	0,56	neutral	0,93	neutral	0,95	neutral	-0,27	0,78	0,22	0,45	disease	0,7	neutral	0,2	neutral	0,32	disease	0,51	0	neutral	0,59	deleterious	0,57	neutral	-3	deleterious	0,58	low_impact	-1,06	medium_impact	0,53	medium_impact	-0,67	0,59	0,8	NA	NA	N	0,35	N	0,59	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5099	5099	C	A	MI.14094	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	630	210	I	M	atC/atA	-0,2	0	0,01	possibly_damaging	0,66	neutral	0,79	neutral	4,6	neutral	-1,94	neutral	-0,15	neutral_impact	0,56	neutral	0,93	neutral	0,95	deleterious	0,2	4,71	0,22	0,45	disease	0,7	neutral	0,2	neutral	0,32	disease	0,51	0	neutral	0,59	deleterious	0,57	neutral	-3	deleterious	0,58	low_impact	-1,06	medium_impact	0,53	medium_impact	-0,67	0,59	0,8	NA	NA	N	0,35	N	0,59	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5100	5100	C	G	MI.14095	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	631	211	L	V	Cta/Gta	-6,88	0	0,01	benign	0,41	neutral	0,44	neutral	4,65	neutral	0,29	neutral	-1,52	low_impact	0,84	neutral	0,88	neutral	0,67	deleterious	3,41	23	0,27	0,45	disease	0,79	neutral	0,41	disease	0,57	disease	0,68	4	neutral	0,5	deleterious	0,52	neutral	-6	deleterious	0,64	medium_impact	-0,65	medium_impact	0,15	medium_impact	-0,44	0,44	0,8	6,92	8,08	N	0,31	N	0,37	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5100	5100	C	A	MI.14096	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	631	211	L	M	Cta/Ata	-6,88	0	0,01	benign	0,3	neutral	1	neutral	4,65	neutral	0,58	neutral	1,09	neutral_impact	-1,22	neutral	0,93	neutral	0,9	neutral	1,01	10,74	0,26	0,45	disease	0,79	neutral	0,02	neutral	0,23	neutral	0,37	3	neutral	0,3	deleterious	0,85	neutral	-6	deleterious	0,48	medium_impact	-0,46	high_impact	1,87	low_impact	-2,17	0,39	0,8	6,92	8,08	N	0,3	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5101	5101	T	C	MI.14097	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	632	211	L	P	cTa/cCa	0,26	0	0	probably_damaging	0,97	neutral	0,21	neutral	4,53	deleterious	-3,77	deleterious	-4,64	medium_impact	1,96	neutral	0,73	neutral	0,37	deleterious	3,94	23,5	0,03	0,35	disease	0,78	disease	0,86	disease	0,7	disease	0,72	4	neutral	0,98	neutral	0,12	deleterious	1	deleterious	0,87	low_impact	-2,18	medium_impact	-0,11	medium_impact	0,51	0,26	0,8	6,92	8,08	N	0,27	N	0,92	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5101	5101	T	A	MI.14098	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	632	211	L	Q	cTa/cAa	0,26	0	0	probably_damaging	0,95	neutral	0,14	neutral	4,53	neutral	-2,16	deleterious	-3,14	medium_impact	2,31	neutral	0,86	neutral	0,52	deleterious	4,11	23,8	0,04	0,35	disease	0,96	disease	0,63	disease	0,57	disease	0,79	6	neutral	0,98	neutral	0,1	deleterious	1	deleterious	0,83	low_impact	-1,97	medium_impact	-0,23	medium_impact	0,8	0,2	0,8	6,92	8,08	N	0,36	N	0,87	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5101	5101	T	G	MI.14099	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	632	211	L	R	cTa/cGa	0,26	0	0	probably_damaging	0,95	neutral	0,2	neutral	4,54	deleterious	-3,16	deleterious	-3,72	medium_impact	2,31	neutral	0,81	neutral	0,46	deleterious	4,18	23,8	0,03	0,35	disease	0,96	disease	0,88	disease	0,69	disease	0,68	4	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,9	low_impact	-1,97	medium_impact	-0,13	medium_impact	0,8	0,15	0,8	6,92	8,08	N	0,29	N	0,9	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8593	8593	A	C	MI.141	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	67	23	I	L	Atc/Ctc	-8,2	0	0	benign	0,09	neutral	0,66	neutral	4,63	neutral	1,49	neutral	-1,09	neutral_impact	0,47	neutral	0,89	neutral	0,4	deleterious	0,64	8,43	0,35	0,65	neutral	0,46	neutral	0,46	neutral	0,38	neutral	0,48	0	neutral	0,24	deleterious	0,79	neutral	-6	neutral	0,22	medium_impact	0,2	medium_impact	0,45	medium_impact	-0,7	0,56	0,9	19,03	10,37	N	0,34	N	0,67	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9190	9190	C	A	MI.1410	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	664	222	L	M	Ctg/Atg	-1,95	0	0	probably_damaging	1	neutral	0,05	neutral	4,09	neutral	-2,89	neutral	-1,76	medium_impact	2,65	neutral	0,65	damaging	0,19	deleterious	4,1	23,7	0,46	0,65	NA	NA	neutral	0,25	neutral	0,43	neutral	0,19	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	-0,43	medium_impact	1,17	0,75	0,9	51,33	8,07	N	0,38	N	0,96	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5103	5103	A	C	MI.14100	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	634	212	T	P	Act/Cct	-2,04	0	0	probably_damaging	0,98	neutral	0,22	neutral	4,57	deleterious	-3,65	deleterious	-5,72	high_impact	3,84	neutral	0,75	neutral	0,52	deleterious	3,51	23,1	0,05	0,35	disease	0,68	disease	0,83	disease	0,81	disease	0,72	4	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,76	low_impact	-2,34	medium_impact	-0,1	high_impact	2,09	0,26	0,8	NA	NA	N	0,44	N	0,97	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5103	5103	A	T	MI.14101	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	634	212	T	S	Act/Tct	-2,04	0	0	probably_damaging	0,91	neutral	0,53	neutral	4,81	neutral	-0,31	deleterious	-3,82	low_impact	1,6	neutral	0,86	neutral	0,68	deleterious	3,33	22,9	0,29	0,45	disease	0,68	disease	0,69	disease	0,61	disease	0,64	3	neutral	0,9	neutral	0,31	neutral	-2	deleterious	0,75	low_impact	-1,72	medium_impact	0,24	medium_impact	0,2	0,43	0,8	NA	NA	N	0,23	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5103	5103	A	G	MI.14102	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	634	212	T	A	Act/Gct	-2,04	0	0	possibly_damaging	0,7	neutral	0,52	neutral	4,63	neutral	-1,19	deleterious	-4,77	medium_impact	2,6	neutral	0,83	neutral	0,65	deleterious	3,53	23,1	0,19	0,45	disease	0,58	disease	0,58	disease	0,65	disease	0,63	3	neutral	0,67	neutral	0,41	NA	0	deleterious	0,68	low_impact	-1,13	medium_impact	0,23	medium_impact	1,04	0,3	0,8	NA	NA	N	0,26	N	0,69	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5104	5104	C	G	MI.14103	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	635	212	T	S	aCt/aGt	8,55	1	0	probably_damaging	0,91	neutral	0,53	neutral	4,81	neutral	-0,31	deleterious	-3,82	low_impact	1,6	neutral	0,86	neutral	0,68	deleterious	3,47	23	0,29	0,45	disease	0,68	disease	0,69	disease	0,61	disease	0,64	3	neutral	0,9	neutral	0,31	neutral	-2	deleterious	0,75	low_impact	-1,72	medium_impact	0,24	medium_impact	0,2	0,43	0,8	NA	NA	P	0,54	P	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5104	5104	C	A	MI.14104	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	635	212	T	N	aCt/aAt	8,55	1	0	probably_damaging	0,98	neutral	0,35	neutral	4,65	neutral	-0,31	deleterious	-4,77	medium_impact	2,13	neutral	0,87	neutral	0,59	deleterious	3,71	23,3	0,25	0,45	disease	0,76	disease	0,81	disease	0,65	disease	0,65	3	deleterious	0,98	neutral	0,19	deleterious	1	deleterious	0,77	low_impact	-2,34	medium_impact	0,06	medium_impact	0,65	0,49	0,8	NA	NA	P	0,63	P	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5104	5104	C	T	MI.14105	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	635	212	T	I	aCt/aTt	8,55	1	0	possibly_damaging	0,8	neutral	0,49	neutral	4,59	neutral	-2,71	deleterious	-5,72	medium_impact	2,15	neutral	0,9	neutral	0,67	deleterious	3,87	23,5	0,12	0,4	disease	0,66	disease	0,84	disease	0,67	disease	0,69	4	neutral	0,78	neutral	0,35	NA	0	deleterious	0,73	low_impact	-1,35	medium_impact	0,2	medium_impact	0,67	0,5	0,8	NA	NA	P	0,62	P	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5106	5106	A	G	MI.14106	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	637	213	T	A	Act/Gct	-10,33	0	0	benign	0,42	neutral	0,53	neutral	4,83	neutral	1,45	neutral	-1,31	neutral_impact	0,41	neutral	0,88	neutral	0,85	deleterious	2,32	18,3	0,26	0,45	neutral	0,41	neutral	0,12	neutral	0,33	neutral	0,28	4	neutral	0,43	deleterious	0,56	neutral	-6	neutral	0,42	medium_impact	-0,67	medium_impact	0,24	medium_impact	-0,8	0,32	0,8	3,46	8,17	N	0,42	N	0,19	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5106	5106	A	C	MI.14107	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	637	213	T	P	Act/Cct	-10,33	0	0	possibly_damaging	0,9	neutral	0,21	neutral	4,54	neutral	-2,95	deleterious	-2,97	medium_impact	2,46	neutral	0,79	neutral	0,35	deleterious	3,48	23,1	0,06	0,35	disease	0,8	disease	0,81	disease	0,6	disease	0,65	3	neutral	0,93	neutral	0,16	NA	0	deleterious	0,79	low_impact	-1,67	medium_impact	-0,11	medium_impact	0,93	0,47	0,8	3,46	8,17	N	0,29	N	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5106	5106	A	T	MI.14108	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	637	213	T	S	Act/Tct	-10,33	0	0	benign	0,06	neutral	0,44	neutral	4,71	neutral	0,65	neutral	-1,29	neutral_impact	-0,26	neutral	0,96	neutral	0,98	neutral	1,66	14,17	0,41	0,5	neutral	0,48	neutral	0,13	neutral	0,25	neutral	0,26	5	neutral	0,51	deleterious	0,69	neutral	-6	neutral	0,17	medium_impact	0,3	medium_impact	0,15	low_impact	-1,36	0,58	0,8	3,46	8,17	N	0,38	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5107	5107	C	G	MI.14109	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	638	213	T	S	aCt/aGt	-5,73	0	0	benign	0,06	neutral	0,44	neutral	4,71	neutral	0,65	neutral	-1,29	neutral_impact	-0,26	neutral	0,96	neutral	0,98	deleterious	1,82	15,12	0,41	0,5	neutral	0,48	neutral	0,13	neutral	0,25	neutral	0,26	5	neutral	0,51	deleterious	0,69	neutral	-6	neutral	0,17	medium_impact	0,3	medium_impact	0,15	low_impact	-1,36	0,58	0,8	3,46	8,17	N	0,44	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9190	9190	C	G	MI.1411	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	664	222	L	V	Ctg/Gtg	-1,95	0	0	probably_damaging	0,99	neutral	0,06	neutral	4,09	neutral	-1,38	deleterious	-2,63	medium_impact	2,78	neutral	0,61	damaging	0,17	deleterious	3,69	23,3	0,4	0,65	NA	NA	neutral	0,28	neutral	0,47	neutral	0,19	6	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,75	low_impact	-2,65	medium_impact	-0,38	medium_impact	1,29	0,48	0,9	51,33	8,07	N	0,36	N	0,87	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5107	5107	C	A	MI.14110	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	638	213	T	N	aCt/aAt	-5,73	0	0	possibly_damaging	0,67	neutral	0,32	neutral	4,55	neutral	-2,46	neutral	-2,5	medium_impact	2,12	neutral	0,85	neutral	0,52	deleterious	3,57	23,1	0,25	0,45	neutral	0,47	disease	0,58	neutral	0,45	neutral	0,42	2	neutral	0,74	neutral	0,33	NA	0	deleterious	0,59	low_impact	-1,08	medium_impact	0,03	medium_impact	0,64	0,51	0,8	3,46	8,17	N	0,33	N	0,52	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5107	5107	C	T	MI.14111	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	638	213	T	I	aCt/aTt	-5,73	0	0	benign	0,06	neutral	0,4	neutral	4,68	neutral	0,36	neutral	0,15	neutral_impact	0,33	neutral	0,9	neutral	0,97	neutral	1,75	14,67	0,13	0,4	disease	0,83	neutral	0,46	neutral	0,31	disease	0,6	2	neutral	0,56	deleterious	0,67	neutral	-6	neutral	0,24	medium_impact	0,3	medium_impact	0,11	medium_impact	-0,87	0,62	0,8	3,46	8,17	N	0,37	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5109	5109	A	T	MI.14112	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	640	214	T	S	Acc/Tcc	-7,57	0	0	benign	0,07	neutral	0,53	neutral	4,59	neutral	-0,7	neutral	-1,1	neutral_impact	0,33	neutral	0,86	neutral	0,98	deleterious	0,42	6,78	0,36	0,5	disease	0,52	neutral	0,23	neutral	0,28	neutral	0,36	3	neutral	0,4	deleterious	0,73	neutral	-6	neutral	0,21	medium_impact	0,23	medium_impact	0,24	medium_impact	-0,87	0,67	0,85	NA	NA	N	0,33	N	0,19	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5109	5109	A	G	MI.14113	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	640	214	T	A	Acc/Gcc	-7,57	0	0	benign	0,02	neutral	0,63	neutral	4,61	neutral	1,13	neutral	-2,08	neutral_impact	0,44	neutral	0,94	neutral	0,99	deleterious	0,71	8,91	0,19	0,45	disease	0,61	neutral	0,12	neutral	0,35	neutral	0,32	4	neutral	0,33	deleterious	0,81	neutral	-6	neutral	0,17	medium_impact	0,75	medium_impact	0,34	medium_impact	-0,77	0,34	0,8	NA	NA	N	0,27	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5109	5109	A	C	MI.14114	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	640	214	T	P	Acc/Ccc	-7,57	0	0	possibly_damaging	0,73	neutral	0,25	neutral	4,49	neutral	-2,97	deleterious	-2,68	low_impact	1,02	neutral	0,9	neutral	0,95	deleterious	2,49	19,42	0,1	0,4	disease	0,68	disease	0,83	neutral	0,48	neutral	0,23	5	neutral	0,82	neutral	0,26	neutral	-3	deleterious	0,78	low_impact	-1,19	medium_impact	-0,06	medium_impact	-0,29	0,31	0,8	NA	NA	N	0,41	N	0,41	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5110	5110	C	T	MI.14115	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	641	214	T	I	aCc/aTc	-2,27	0	0	possibly_damaging	0,66	neutral	0,46	neutral	4,6	neutral	-0,37	deleterious	-3,9	low_impact	1,54	neutral	0,87	neutral	0,49	deleterious	3,59	23,2	0,14	0,4	neutral	0,43	disease	0,75	disease	0,55	disease	0,66	3	neutral	0,65	neutral	0,4	neutral	-3	deleterious	0,68	low_impact	-1,06	medium_impact	0,17	medium_impact	0,15	0,59	0,8	NA	NA	N	0,26	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5110	5110	C	G	MI.14116	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	641	214	T	S	aCc/aGc	-2,27	0	0	benign	0,07	neutral	0,53	neutral	4,59	neutral	-0,7	neutral	-1,1	neutral_impact	0,33	neutral	0,86	neutral	0,98	deleterious	0,1	3,56	0,36	0,5	disease	0,52	neutral	0,23	neutral	0,28	neutral	0,36	3	neutral	0,4	deleterious	0,73	neutral	-6	neutral	0,21	medium_impact	0,23	medium_impact	0,24	medium_impact	-0,87	0,67	0,85	NA	NA	N	0,33	N	0,19	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5110	5110	C	A	MI.14117	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	641	214	T	N	aCc/aAc	-2,27	0	0	possibly_damaging	0,66	neutral	0,38	neutral	4,51	neutral	-1,76	neutral	-2,18	low_impact	1,78	neutral	0,91	neutral	0,63	deleterious	3,37	22,9	0,25	0,45	disease	0,87	disease	0,75	disease	0,57	disease	0,67	3	neutral	0,69	neutral	0,36	neutral	-3	deleterious	0,71	low_impact	-1,06	medium_impact	0,09	medium_impact	0,35	0,45	0,8	NA	NA	N	0,34	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5112	5112	G	C	MI.14118	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	643	215	A	P	Gca/Cca	-14,47	0	0	benign	0,33	neutral	0,15	neutral	4,57	neutral	-2,69	neutral	-1,34	neutral_impact	0,7	neutral	0,85	neutral	0,38	deleterious	2,25	17,81	0,04	0,35	disease	0,83	disease	0,82	disease	0,69	disease	0,72	4	neutral	0,82	neutral	0,41	neutral	-6	deleterious	0,6	medium_impact	-0,52	medium_impact	-0,21	medium_impact	-0,56	0,46	0,8	2,02	7,82	N	0,27	N	0,79	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5112	5112	G	T	MI.14119	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	643	215	A	S	Gca/Tca	-14,47	0	0	benign	0,02	neutral	0,38	neutral	4,62	neutral	-0,36	neutral	0,1	neutral_impact	0,7	neutral	0,8	neutral	0,81	neutral	1,79	14,9	0,3	0,45	disease	0,65	neutral	0,4	disease	0,52	disease	0,63	3	neutral	0,6	deleterious	0,68	neutral	-6	neutral	0,2	medium_impact	0,75	medium_impact	0,09	medium_impact	-0,56	0,31	0,8	2,02	7,82	N	0,37	N	0,56	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9191	9191	T	A	MI.1412	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	665	222	L	Q	cTg/cAg	-2,65	0	0	probably_damaging	1	deleterious	0,02	neutral	3,99	deleterious	-5,72	deleterious	-5,28	high_impact	3,75	damaging	0,45	damaging	0,15	deleterious	4,51	24,3	0,27	0,65	NA	NA	disease	0,58	disease	0,59	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,6	medium_impact	-0,66	high_impact	2,12	0,5	0,9	51,33	8,07	N	0,34	N	0,98	polymorphism	0,87	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5112	5112	G	A	MI.14120	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	643	215	A	T	Gca/Aca	-14,47	0	0	benign	0	neutral	0,4	neutral	4,64	neutral	0,01	neutral	1,07	neutral_impact	-0,83	neutral	0,94	neutral	0,98	deleterious	-0,06	2,01	0,18	0,45	disease	0,54	neutral	0,15	neutral	0,28	neutral	0,3	4	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,14	medium_impact	1,95	medium_impact	0,11	low_impact	-1,84	0,8	0,85	2,02	7,82	N	0,4	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5113	5113	C	A	MI.14121	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	644	215	A	E	gCa/gAa	-2,04	0	0	benign	0,17	neutral	0,19	neutral	4,57	neutral	-2,33	neutral	-1,3	low_impact	1,8	neutral	0,91	neutral	0,6	deleterious	2,71	20,9	0,03	0,35	disease	0,77	disease	0,75	disease	0,67	disease	0,72	4	neutral	0,78	deleterious	0,51	neutral	-6	neutral	0,37	medium_impact	-0,17	medium_impact	-0,14	medium_impact	0,37	0,28	0,8	2,02	7,82	N	0,36	N	0,8	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5113	5113	C	G	MI.14122	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	644	215	A	G	gCa/gGa	-2,04	0	0	benign	0,13	neutral	0,26	neutral	4,57	neutral	-2,17	neutral	-2,06	low_impact	1,46	neutral	0,89	neutral	0,6	deleterious	2,12	16,96	0,23	0,45	disease	0,78	neutral	0,44	disease	0,54	disease	0,67	3	neutral	0,7	deleterious	0,57	neutral	-6	neutral	0,28	medium_impact	-0,04	medium_impact	-0,04	medium_impact	0,09	0,5	0,8	2,02	7,82	N	0,42	N	0,57	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5113	5113	C	T	MI.14123	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	644	215	A	V	gCa/gTa	-2,04	0	0	benign	0,05	neutral	0,49	neutral	4,71	neutral	0,79	neutral	0,73	neutral_impact	-0,44	neutral	0,8	neutral	0,8	neutral	1,31	12,3	0,2	0,45	neutral	0,44	neutral	0,16	neutral	0,34	neutral	0,3	4	neutral	0,46	deleterious	0,72	neutral	-6	neutral	0,16	medium_impact	0,37	medium_impact	0,2	low_impact	-1,52	0,72	0,85	2,02	7,82	N	0,31	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5115	5115	T	C	MI.14124	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	646	216	F	L	Ttc/Ctc	-1,12	0	0	benign	0,09	neutral	0,59	neutral	2,74	deleterious	-5,12	deleterious	-5,52	medium_impact	2,1	neutral	0,92	damaging	0,22	deleterious	4,06	23,7	0,15	0,4	neutral	0,12	disease	0,8	disease	0,68	disease	0,55	1	neutral	0,32	deleterious	0,75	neutral	-3	neutral	0,27	medium_impact	0,12	medium_impact	0,3	medium_impact	0,62	0,36	0,8	0,29	7,08	N	0,26	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5115	5115	T	A	MI.14125	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	646	216	F	I	Ttc/Atc	-1,12	0	0	possibly_damaging	0,77	neutral	0,48	neutral	2,65	deleterious	-7,21	deleterious	-5,57	low_impact	1,63	neutral	0,91	damaging	0,13	deleterious	4,44	24,2	0,15	0,4	neutral	0,43	disease	0,79	disease	0,75	disease	0,68	4	neutral	0,75	neutral	0,36	neutral	-3	deleterious	0,73	low_impact	-1,28	medium_impact	0,19	medium_impact	0,23	0,39	0,8	0,29	7,08	N	0,38	N	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5115	5115	T	G	MI.14126	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	646	216	F	V	Ttc/Gtc	-1,12	0	0	possibly_damaging	0,77	neutral	0,27	neutral	2,64	deleterious	-7,46	deleterious	-6,51	medium_impact	2,1	neutral	0,78	damaging	0,13	deleterious	4,17	23,8	0,13	0,4	neutral	0,43	disease	0,81	disease	0,75	disease	0,69	4	neutral	0,83	neutral	0,25	NA	0	deleterious	0,72	low_impact	-1,28	medium_impact	-0,03	medium_impact	0,62	0,25	0,8	0,29	7,08	N	0,29	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5116	5116	T	C	MI.14127	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	647	216	F	S	tTc/tCc	4,63	1	0	probably_damaging	0,96	neutral	0,22	neutral	2,63	deleterious	-9	deleterious	-7,52	medium_impact	2,52	neutral	0,9	damaging	0,17	deleterious	4,32	24	0,07	0,35	disease	0,56	disease	0,83	disease	0,73	disease	0,7	4	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,8	low_impact	-2,06	medium_impact	-0,1	medium_impact	0,98	0,28	0,8	0,29	7,08	N	0,52	P	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5116	5116	T	A	MI.14128	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	647	216	F	Y	tTc/tAc	4,63	1	0	probably_damaging	0,93	neutral	0,53	neutral	2,69	deleterious	-5,93	deleterious	-2,83	medium_impact	2,73	neutral	0,84	damaging	0,11	deleterious	4,46	24,2	0,2	0,45	neutral	0,37	disease	0,74	disease	0,71	disease	0,68	4	neutral	0,92	neutral	0,3	deleterious	1	deleterious	0,75	low_impact	-1,83	medium_impact	0,24	medium_impact	1,15	0,37	0,8	0,29	7,08	N	0,48	N	0,88	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5116	5116	T	G	MI.14129	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	647	216	F	C	tTc/tGc	4,63	1	0	probably_damaging	0,99	neutral	0,08	neutral	2,62	deleterious	-10,27	deleterious	-7,5	medium_impact	2,38	neutral	0,83	damaging	0,13	deleterious	4,14	23,8	0,08	0,35	disease	0,79	disease	0,83	disease	0,75	disease	0,68	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,81	low_impact	-2,62	medium_impact	-0,38	medium_impact	0,86	0,15	0,8	0,29	7,08	N	0,44	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9191	9191	T	C	MI.1413	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	665	222	L	P	cTg/cCg	-2,65	0	0	probably_damaging	1	deleterious	0,01	neutral	3,99	deleterious	-6,08	deleterious	-6,17	high_impact	4,1	damaging	0,27	damaging	0,15	deleterious	4,23	23,9	0,22	0,65	NA	NA	disease	0,56	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,6	medium_impact	-0,84	high_impact	2,42	0,41	0,9	51,33	8,07	P	0,75	P	1	disease_causing_automatic	1	0,28	rs386829069	Pathogenic	Leigh_syndrome	RCV000144006.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	T9191C	Leigh Disease	-	+	Reported	1
chrM	5117	5117	C	A	MI.14130	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	648	216	F	L	ttC/ttA	7,4	1	0	benign	0,09	neutral	0,59	neutral	2,74	deleterious	-5,12	deleterious	-5,52	medium_impact	2,1	neutral	0,92	damaging	0,22	deleterious	4,71	24,6	0,15	0,4	neutral	0,12	disease	0,8	disease	0,68	disease	0,55	1	neutral	0,32	deleterious	0,75	neutral	-3	neutral	0,27	medium_impact	0,12	medium_impact	0,3	medium_impact	0,62	0,36	0,8	0,29	7,08	N	0,51	P	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5117	5117	C	G	MI.14131	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	648	216	F	L	ttC/ttG	7,4	1	0	benign	0,09	neutral	0,59	neutral	2,74	deleterious	-5,12	deleterious	-5,52	medium_impact	2,1	neutral	0,92	damaging	0,22	deleterious	4,39	24,1	0,15	0,4	neutral	0,12	disease	0,8	disease	0,68	disease	0,55	1	neutral	0,32	deleterious	0,75	neutral	-3	neutral	0,27	medium_impact	0,12	medium_impact	0,3	medium_impact	0,62	0,36	0,8	0,29	7,08	N	0,51	P	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5118	5118	C	G	MI.14132	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	649	217	L	V	Cta/Gta	-2,5	0	0	possibly_damaging	0,79	neutral	0,58	neutral	4,42	neutral	-1,98	neutral	-0,92	low_impact	1,74	neutral	0,93	neutral	0,7	deleterious	3,39	23	0,33	0,5	neutral	0,28	neutral	0,38	disease	0,57	neutral	0,46	1	neutral	0,76	neutral	0,4	neutral	-3	deleterious	0,57	low_impact	-1,32	medium_impact	0,29	medium_impact	0,32	0,62	0,8	3,46	7,39	N	0,33	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5118	5118	C	A	MI.14133	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	649	217	L	M	Cta/Ata	-2,5	0	0	possibly_damaging	0,46	neutral	0,36	neutral	4,38	neutral	-1,98	neutral	1,78	neutral_impact	0,26	neutral	0,85	neutral	0,86	neutral	1,04	10,87	0,25	0,45	neutral	0,19	neutral	0,09	neutral	0,26	neutral	0,26	5	neutral	0,6	neutral	0,45	neutral	-3	neutral	0,36	medium_impact	-0,73	medium_impact	0,07	medium_impact	-0,93	0,39	0,8	3,46	7,39	N	0,42	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5119	5119	T	G	MI.14134	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	650	217	L	R	cTa/cGa	-2,96	0	0	probably_damaging	0,98	neutral	0,31	neutral	4,29	deleterious	-5,01	deleterious	-2,77	medium_impact	2,71	neutral	0,81	neutral	0,44	deleterious	4,23	23,9	0,02	0,35	disease	0,64	disease	0,82	disease	0,7	disease	0,68	4	neutral	0,98	neutral	0,17	deleterious	1	deleterious	0,83	low_impact	-2,34	medium_impact	0,02	medium_impact	1,14	0,15	0,8	3,46	7,39	N	0,27	N	0,62	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5119	5119	T	C	MI.14135	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	650	217	L	P	cTa/cCa	-2,96	0	0	probably_damaging	0,99	neutral	0,18	neutral	4,29	deleterious	-5,36	deleterious	-3,57	medium_impact	2,5	neutral	0,76	neutral	0,4	deleterious	3,93	23,5	0,02	0,35	disease	0,72	disease	0,81	disease	0,71	disease	0,69	4	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,85	low_impact	-2,62	medium_impact	-0,16	medium_impact	0,96	0,24	0,8	3,46	7,39	N	0,29	N	0,86	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5119	5119	T	A	MI.14136	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	650	217	L	Q	cTa/cAa	-2,96	0	0	probably_damaging	0,98	neutral	0,29	neutral	4,29	deleterious	-5,15	neutral	-2,06	medium_impact	2,16	neutral	0,83	neutral	0,51	deleterious	4,1	23,7	0,03	0,35	disease	0,66	disease	0,72	disease	0,57	disease	0,63	3	neutral	0,98	neutral	0,16	deleterious	1	deleterious	0,77	low_impact	-2,34	medium_impact	-0,01	medium_impact	0,67	0,23	0,8	3,46	7,39	N	0,3	N	0,56	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5121	5121	C	G	MI.14137	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	652	218	L	V	Cta/Gta	-7,34	0	0	benign	0,02	neutral	0,54	neutral	4,45	neutral	-0,26	neutral	-1,89	low_impact	1,3	neutral	0,92	neutral	0,89	deleterious	0,37	6,38	0,32	0,5	NA	NA	neutral	0,17	neutral	0,25	neutral	0,2	6	neutral	0,43	deleterious	0,76	neutral	-6	neutral	0,12	medium_impact	0,75	medium_impact	0,25	medium_impact	-0,05	0,57	0,8	7,2	8,74	N	0,4	N	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5121	5121	C	A	MI.14138	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	652	218	L	M	Cta/Ata	-7,34	0	0	benign	0,02	neutral	0,34	neutral	4,34	neutral	-2,29	neutral	-1,06	neutral_impact	0,62	neutral	0,86	neutral	0,94	deleterious	1,9	15,57	0,26	0,45	NA	NA	neutral	0,08	neutral	0,23	neutral	0,19	6	neutral	0,64	deleterious	0,66	neutral	-6	neutral	0,11	medium_impact	0,75	medium_impact	0,05	medium_impact	-0,62	0,41	0,8	7,2	8,74	N	0,51	P	0,05	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5122	5122	T	G	MI.14139	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	653	218	L	R	cTa/cGa	-3,42	0	0	benign	0,23	neutral	0,36	neutral	4,32	deleterious	-4,42	deleterious	-4,78	medium_impact	2,44	neutral	0,89	neutral	0,42	deleterious	3,81	23,4	0,02	0,35	NA	NA	disease	0,67	disease	0,57	disease	0,65	3	neutral	0,57	deleterious	0,57	neutral	-3	deleterious	0,54	medium_impact	-0,32	medium_impact	0,07	medium_impact	0,91	0,28	0,8	7,2	8,74	N	0,38	N	0,42	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9191	9191	T	G	MI.1414	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	665	222	L	R	cTg/cGg	-2,65	0	0	probably_damaging	1	deleterious	0,02	neutral	4	deleterious	-5,36	deleterious	-5,28	high_impact	3,75	damaging	0,37	damaging	0,13	deleterious	4,53	24,3	0,24	0,65	NA	NA	disease	0,66	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,6	medium_impact	-0,66	high_impact	2,12	0,52	0,9	51,33	8,07	N	0,44	N	0,99	polymorphism	0,84	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5122	5122	T	C	MI.14140	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	653	218	L	P	cTa/cCa	-3,42	0	0	benign	0,23	neutral	0,21	neutral	4,31	deleterious	-4,95	deleterious	-5,52	low_impact	1,75	neutral	0,77	neutral	0,3	deleterious	3,58	23,2	0,02	0,35	NA	NA	disease	0,73	disease	0,59	disease	0,65	3	neutral	0,75	deleterious	0,49	neutral	-6	deleterious	0,55	medium_impact	-0,32	medium_impact	-0,11	medium_impact	0,33	0,33	0,8	7,2	8,74	N	0,29	N	0,72	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5122	5122	T	A	MI.14141	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	653	218	L	Q	cTa/cAa	-3,42	0	0	benign	0,41	neutral	0,32	neutral	4,37	deleterious	-3,99	deleterious	-4,62	medium_impact	2,79	neutral	0,87	neutral	0,47	deleterious	3,95	23,6	0,04	0,35	NA	NA	disease	0,5	neutral	0,43	neutral	0,44	1	neutral	0,63	neutral	0,46	neutral	-3	deleterious	0,5	medium_impact	-0,65	medium_impact	0,03	medium_impact	1,2	0,28	0,8	7,2	8,74	N	0,42	N	0,42	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5124	5124	C	G	MI.14142	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	655	219	L	V	Ctc/Gtc	-7,8	0	0	possibly_damaging	0,82	neutral	0,54	neutral	4,67	neutral	-0,19	neutral	-2,11	medium_impact	3,02	neutral	0,92	neutral	0,64	deleterious	3,46	23	0,31	0,45	neutral	0,21	neutral	0,35	disease	0,63	neutral	0,45	1	neutral	0,8	neutral	0,36	NA	0	deleterious	0,63	low_impact	-1,4	medium_impact	0,25	medium_impact	1,4	0,54	0,8	NA	NA	N	0,36	N	0,33	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5124	5124	C	A	MI.14143	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	655	219	L	I	Ctc/Atc	-7,8	0	0	possibly_damaging	0,77	neutral	0,49	neutral	4,55	neutral	-0,77	neutral	-1,16	low_impact	1,64	neutral	0,91	neutral	0,8	deleterious	3,04	22,4	0,3	0,45	neutral	0,36	neutral	0,35	neutral	0,35	neutral	0,44	1	neutral	0,75	neutral	0,36	neutral	-3	deleterious	0,65	low_impact	-1,28	medium_impact	0,2	medium_impact	0,24	0,48	0,8	NA	NA	N	0,38	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5124	5124	C	T	MI.14144	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	655	219	L	F	Ctc/Ttc	-7,8	0	0	benign	0,09	neutral	0,89	neutral	4,48	neutral	-2,1	neutral	-0,7	neutral_impact	0,04	neutral	0,9	neutral	0,92	deleterious	2,04	16,48	0,22	0,45	neutral	0,38	neutral	0,19	neutral	0,35	neutral	0,32	4	neutral	0,04	deleterious	0,9	neutral	-6	neutral	0,25	medium_impact	0,12	medium_impact	0,71	low_impact	-1,11	0,36	0,8	NA	NA	N	0,31	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5125	5125	T	C	MI.14145	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	656	219	L	P	cTc/cCc	-0,89	0	0	probably_damaging	0,99	neutral	0,21	neutral	4,41	deleterious	-4,84	deleterious	-5,68	medium_impact	3,36	neutral	0,75	neutral	0,36	deleterious	4	23,6	0,01	0,35	neutral	0,38	disease	0,78	disease	0,76	disease	0,69	4	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,78	low_impact	-2,62	medium_impact	-0,11	medium_impact	1,68	0,23	0,8	NA	NA	N	0,4	N	0,94	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5125	5125	T	A	MI.14146	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	656	219	L	H	cTc/cAc	-0,89	0	0	probably_damaging	0,99	neutral	0,55	neutral	4,42	deleterious	-3,59	deleterious	-4,7	medium_impact	3,02	neutral	0,9	neutral	0,6	deleterious	4,29	24	0,04	0,35	disease	0,73	disease	0,72	disease	0,71	disease	0,69	4	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,8	low_impact	-2,62	medium_impact	0,26	medium_impact	1,4	0,28	0,8	NA	NA	N	0,32	N	0,82	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5125	5125	T	G	MI.14147	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	656	219	L	R	cTc/cGc	-0,89	0	0	probably_damaging	0,98	neutral	0,34	neutral	4,42	deleterious	-4,07	deleterious	-4,76	medium_impact	3,02	neutral	0,81	neutral	0,41	deleterious	4,22	23,9	0,01	0,35	disease	0,64	disease	0,8	disease	0,76	disease	0,7	4	deleterious	0,98	neutral	0,18	deleterious	1	deleterious	0,82	low_impact	-2,34	medium_impact	0,05	medium_impact	1,4	0,21	0,8	NA	NA	N	0,34	N	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5127	5127	A	T	MI.14148	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	658	220	N	Y	Aac/Tac	-6,65	0	0,01	benign	0,02	neutral	1	neutral	4,53	neutral	-2,94	neutral	-0,42	low_impact	1,46	neutral	0,92	neutral	0,81	neutral	1	10,66	0,14	0,4	disease	0,67	disease	0,51	neutral	0,36	disease	0,5	0	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,17	medium_impact	0,75	high_impact	1,87	medium_impact	0,09	0,21	0,8	15,27	9,25	N	0,21	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5127	5127	A	G	MI.14149	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	658	220	N	D	Aac/Gac	-6,65	0	0,01	benign	0,02	neutral	0,21	neutral	4,59	neutral	-0,81	neutral	-1,59	low_impact	1,83	neutral	0,87	neutral	0,74	deleterious	0,61	8,23	0,46	0,55	disease	0,54	neutral	0,45	disease	0,56	disease	0,61	2	neutral	0,78	deleterious	0,6	neutral	-6	neutral	0,16	medium_impact	0,75	medium_impact	-0,11	medium_impact	0,4	0,25	0,8	15,27	9,25	N	0,39	N	0,06	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9193	9193	C	A	MI.1415	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	667	223	H	N	Cac/Aac	1,29	1	0	probably_damaging	0,98	neutral	0,59	neutral	4,5	neutral	2,01	deleterious	-3,65	neutral_impact	-0,67	neutral	0,88	neutral	0,47	deleterious	4,19	23,8	0,83	0,85	NA	NA	neutral	0,37	neutral	0,48	neutral	0,15	7	neutral	0,98	neutral	0,31	neutral	-2	deleterious	0,74	low_impact	-2,36	medium_impact	0,38	low_impact	-1,67	0,55	0,9	NA	NA	N	0,35	N	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5127	5127	A	C	MI.14150	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	658	220	N	H	Aac/Cac	-6,65	0	0,01	possibly_damaging	0,81	neutral	0,54	neutral	4,54	neutral	-2,23	neutral	-0,65	low_impact	1,56	neutral	0,9	neutral	0,88	neutral	1,15	11,5	0,32	0,5	disease	0,72	neutral	0,48	neutral	0,46	disease	0,6	2	neutral	0,78	neutral	0,37	neutral	-3	deleterious	0,65	low_impact	-1,37	medium_impact	0,25	medium_impact	0,17	0,23	0,8	15,27	9,25	N	0,36	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5128	5128	A	C	MI.14151	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	659	220	N	T	aAc/aCc	0,95	0	0	possibly_damaging	0,52	neutral	0,43	neutral	4,59	neutral	-0,74	neutral	-0,48	low_impact	1,12	neutral	0,9	neutral	0,94	neutral	1,34	12,47	0,29	0,45	disease	0,52	neutral	0,32	neutral	0,45	neutral	0,36	3	neutral	0,57	neutral	0,46	neutral	-3	deleterious	0,51	medium_impact	-0,83	medium_impact	0,14	medium_impact	-0,2	0,27	0,8	15,27	9,25	N	0,48	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5128	5128	A	G	MI.14152	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	659	220	N	S	aAc/aGc	0,95	0	0	benign	0,26	neutral	0,47	neutral	4,63	neutral	-0,18	neutral	-0,36	low_impact	1,17	neutral	0,9	neutral	0,85	neutral	-0,26	0,83	0,48	0,55	neutral	0,42	neutral	0,37	neutral	0,44	neutral	0,46	1	neutral	0,43	deleterious	0,61	neutral	-6	deleterious	0,44	medium_impact	-0,38	medium_impact	0,18	medium_impact	-0,16	0,28	0,8	15,27	9,25	N	0,41	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5128	5128	A	T	MI.14153	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	659	220	N	I	aAc/aTc	0,95	0	0	possibly_damaging	0,75	neutral	0,48	neutral	4,58	neutral	-0,96	neutral	0,35	neutral_impact	0,62	neutral	0,87	neutral	0,96	deleterious	1,99	16,15	0,16	0,45	disease	0,62	neutral	0,31	neutral	0,34	disease	0,61	2	neutral	0,73	neutral	0,37	neutral	-3	deleterious	0,6	low_impact	-1,23	medium_impact	0,19	medium_impact	-0,62	0,2	0,8	15,27	9,25	N	0,42	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5129	5129	C	G	MI.14154	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	660	220	N	K	aaC/aaG	-0,89	0	0	possibly_damaging	0,44	neutral	0,39	neutral	4,64	neutral	-0,09	neutral	-1,14	neutral_impact	0,6	neutral	0,87	neutral	0,75	deleterious	0,81	9,51	0,4	0,5	neutral	0,4	neutral	0,31	neutral	0,46	neutral	0,46	1	neutral	0,56	deleterious	0,48	neutral	-3	deleterious	0,5	medium_impact	-0,7	medium_impact	0,1	medium_impact	-0,64	0,35	0,8	15,27	9,25	N	0,38	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5129	5129	C	A	MI.14155	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	660	220	N	K	aaC/aaA	-0,89	0	0	possibly_damaging	0,44	neutral	0,39	neutral	4,64	neutral	-0,09	neutral	-1,14	neutral_impact	0,6	neutral	0,87	neutral	0,75	neutral	1,24	11,95	0,4	0,5	neutral	0,4	neutral	0,31	neutral	0,46	neutral	0,46	1	neutral	0,56	deleterious	0,48	neutral	-3	deleterious	0,5	medium_impact	-0,7	medium_impact	0,1	medium_impact	-0,64	0,35	0,8	15,27	9,25	N	0,39	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5130	5130	T	G	MI.14156	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	661	221	L	V	Tta/Gta	-5,96	0	0	possibly_damaging	0,66	neutral	0,51	neutral	4,53	neutral	-1,27	neutral	-0,53	low_impact	1,08	neutral	0,92	neutral	0,85	deleterious	0,35	6,16	0,4	0,5	disease	0,66	neutral	0,1	neutral	0,37	neutral	0,38	2	neutral	0,63	neutral	0,43	neutral	-3	deleterious	0,55	low_impact	-1,06	medium_impact	0,22	medium_impact	-0,24	0,48	0,8	20,46	10,41	N	0,42	N	0,3	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5130	5130	T	A	MI.14157	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	661	221	L	M	Tta/Ata	-5,96	0	0	benign	0,3	neutral	0,34	neutral	4,45	neutral	-2,16	neutral	0,27	neutral_impact	0,55	neutral	0,91	neutral	0,94	deleterious	0,28	5,5	0,32	0,5	disease	0,78	neutral	0,08	neutral	0,26	neutral	0,37	3	neutral	0,59	deleterious	0,52	neutral	-6	neutral	0,42	medium_impact	-0,46	medium_impact	0,05	medium_impact	-0,68	0,56	0,8	20,46	10,41	N	0,55	P	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5131	5131	T	G	MI.14158	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	662	221	L	W	tTa/tGa	-5,73	0	0	probably_damaging	0,98	neutral	0,17	neutral	4,38	deleterious	-5,58	neutral	-1,24	low_impact	1,43	neutral	0,87	neutral	0,44	deleterious	2,6	20,2	0,07	0,35	disease	0,94	neutral	0,36	neutral	0,37	disease	0,57	1	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,74	low_impact	-2,34	medium_impact	-0,17	medium_impact	0,06	0,21	0,8	20,46	10,41	N	0,43	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5131	5131	T	C	MI.14159	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	662	221	L	S	tTa/tCa	-5,73	0	0	benign	0,3	neutral	0,57	neutral	4,57	deleterious	-3,35	neutral	-1,2	neutral_impact	0,17	neutral	0,73	neutral	0,9	deleterious	2,17	17,33	0,07	0,35	disease	0,62	neutral	0,14	neutral	0,31	neutral	0,34	3	neutral	0,33	deleterious	0,64	neutral	-6	neutral	0,38	medium_impact	-0,46	medium_impact	0,28	low_impact	-1	0,29	0,8	20,46	10,41	N	0,31	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9193	9193	C	G	MI.1416	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	667	223	H	D	Cac/Gac	1,29	1	0	probably_damaging	0,99	neutral	0,33	neutral	4,41	neutral	0,69	deleterious	-4,85	neutral_impact	-0,82	neutral	0,79	neutral	0,39	deleterious	4,18	23,8	0,45	0,65	NA	NA	neutral	0,4	disease	0,55	neutral	0,32	4	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,77	low_impact	-2,65	medium_impact	0,12	low_impact	-1,8	0,48	0,9	NA	NA	N	0,3	N	0,95	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5132	5132	A	T	MI.14160	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	663	221	L	F	ttA/ttT	-4,58	0	0	probably_damaging	0,91	neutral	0,78	neutral	4,44	neutral	-2,86	neutral	0,23	neutral_impact	-0,04	neutral	0,84	neutral	0,95	neutral	1,24	11,94	0,27	0,45	disease	0,82	neutral	0,16	neutral	0,26	neutral	0,37	3	neutral	0,9	neutral	0,44	neutral	-2	deleterious	0,67	low_impact	-1,72	medium_impact	0,51	low_impact	-1,18	0,5	0,8	20,46	10,41	N	0,32	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5132	5132	A	C	MI.14161	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	663	221	L	F	ttA/ttC	-4,58	0	0	probably_damaging	0,91	neutral	0,78	neutral	4,44	neutral	-2,86	neutral	0,23	neutral_impact	-0,04	neutral	0,84	neutral	0,95	neutral	1,07	11,06	0,27	0,45	disease	0,82	neutral	0,16	neutral	0,26	neutral	0,37	3	neutral	0,9	neutral	0,44	neutral	-2	deleterious	0,67	low_impact	-1,72	medium_impact	0,51	low_impact	-1,18	0,5	0,8	20,46	10,41	N	0,31	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5133	5133	A	G	MI.14162	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	664	222	N	D	Aac/Gac	-12,86	0	0	benign	0,32	neutral	0,21	neutral	4,62	neutral	-1,58	deleterious	-3,17	medium_impact	2,04	neutral	0,91	neutral	0,45	deleterious	1,97	16,01	0,5	0,6	disease	0,66	neutral	0,31	neutral	0,45	disease	0,6	2	neutral	0,75	neutral	0,45	neutral	-3	neutral	0,38	medium_impact	-0,5	medium_impact	-0,11	medium_impact	0,57	0,23	0,8	4,61	7,9	N	0,42	N	0,64	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5133	5133	A	T	MI.14163	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	664	222	N	Y	Aac/Tac	-12,86	0	0	possibly_damaging	0,87	neutral	1	neutral	4,64	neutral	-0,17	deleterious	-4,54	low_impact	0,88	neutral	0,94	neutral	0,77	deleterious	2,13	17,07	0,15	0,4	disease	0,8	neutral	0,34	neutral	0,29	disease	0,64	3	neutral	0,87	deleterious	0,57	neutral	-3	deleterious	0,67	low_impact	-1,55	high_impact	1,87	medium_impact	-0,4	0,21	0,8	4,61	7,9	N	0,27	N	0,33	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5133	5133	A	C	MI.14164	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	664	222	N	H	Aac/Cac	-12,86	0	0	possibly_damaging	0,87	neutral	0,54	neutral	4,62	neutral	-1,1	deleterious	-2,61	low_impact	1,5	neutral	0,89	neutral	0,91	neutral	1,54	13,51	0,35	0,5	disease	0,59	neutral	0,32	neutral	0,32	disease	0,61	2	neutral	0,86	neutral	0,34	neutral	-3	deleterious	0,64	low_impact	-1,55	medium_impact	0,25	medium_impact	0,12	0,19	0,8	4,61	7,9	N	0,33	N	0,4	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5134	5134	A	C	MI.14165	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	665	222	N	T	aAc/aCc	-0,89	0	0	benign	0,32	neutral	0,42	neutral	4,67	neutral	0,74	deleterious	-3,12	neutral_impact	-0,26	neutral	0,84	neutral	0,99	deleterious	0	2,62	0,31	0,45	neutral	0,45	neutral	0,07	neutral	0,26	neutral	0,25	5	neutral	0,5	deleterious	0,55	neutral	-6	neutral	0,32	medium_impact	-0,5	medium_impact	0,13	low_impact	-1,36	0,26	0,8	4,61	7,9	N	0,41	N	0,46	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5134	5134	A	T	MI.14166	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	665	222	N	I	aAc/aTc	-0,89	0	0	possibly_damaging	0,77	neutral	0,42	neutral	4,88	neutral	2,99	deleterious	-5,65	low_impact	0,86	neutral	0,83	neutral	0,76	deleterious	2,29	18,11	0,16	0,45	disease	0,7	neutral	0,24	neutral	0,3	disease	0,56	1	neutral	0,77	neutral	0,33	neutral	-3	deleterious	0,6	low_impact	-1,28	medium_impact	0,13	medium_impact	-0,42	0,09	0,8	4,61	7,9	N	0,36	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5134	5134	A	G	MI.14167	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	665	222	N	S	aAc/aGc	-0,89	0	0	benign	0,01	neutral	0,45	neutral	4,69	neutral	1,13	neutral	-2,34	neutral_impact	0,3	neutral	0,93	neutral	0,99	neutral	-0,66	0,09	0,45	0,55	neutral	0,4	neutral	0,12	neutral	0,29	neutral	0,3	4	neutral	0,53	deleterious	0,72	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	0,16	medium_impact	-0,89	0,23	0,8	4,61	7,9	N	0,44	N	0,09	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5135	5135	C	G	MI.14168	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	666	222	N	K	aaC/aaG	-0,66	0	0	possibly_damaging	0,44	neutral	0,3	neutral	4,63	neutral	-0,43	deleterious	-3,63	low_impact	1,07	neutral	0,89	neutral	0,48	neutral	1,11	11,3	0,44	0,55	disease	0,54	neutral	0,35	neutral	0,45	neutral	0,44	1	neutral	0,66	neutral	0,43	neutral	-3	neutral	0,41	medium_impact	-0,7	medium_impact	0	medium_impact	-0,24	0,26	0,8	4,61	7,9	N	0,44	N	0,72	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5135	5135	C	A	MI.14169	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	666	222	N	K	aaC/aaA	-0,66	0	0	possibly_damaging	0,44	neutral	0,3	neutral	4,63	neutral	-0,43	deleterious	-3,63	low_impact	1,07	neutral	0,89	neutral	0,48	neutral	1,52	13,41	0,44	0,55	disease	0,54	neutral	0,35	neutral	0,45	neutral	0,44	1	neutral	0,66	neutral	0,43	neutral	-3	neutral	0,41	medium_impact	-0,7	medium_impact	0	medium_impact	-0,24	0,26	0,8	4,61	7,9	N	0,44	N	0,72	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9193	9193	C	T	MI.1417	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	667	223	H	Y	Cac/Tac	1,29	1	0	probably_damaging	0,98	deleterious	0,01	neutral	4,37	neutral	-1,3	deleterious	-3,42	low_impact	1,15	neutral	0,94	neutral	0,55	deleterious	3,95	23,6	0,63	0,7	NA	NA	neutral	0,34	disease	0,52	neutral	0,3	4	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,77	low_impact	-2,36	medium_impact	-0,84	medium_impact	-0,11	0,4	0,9	NA	NA	N	0,43	N	0,93	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5136	5136	T	C	MI.14170	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	667	223	S	P	Tcc/Ccc	-5,27	0	0	probably_damaging	1	neutral	0,28	neutral	4,57	neutral	-2,49	deleterious	-4,04	medium_impact	2,38	neutral	0,91	damaging	0,17	deleterious	4,08	23,7	0,11	0,4	disease	0,78	disease	0,84	disease	0,53	disease	0,75	5	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	-0,02	medium_impact	0,86	0,11	0,8	2,88	7,74	N	0,36	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5136	5136	T	A	MI.14171	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	667	223	S	T	Tcc/Acc	-5,27	0	0	probably_damaging	1	neutral	0,57	neutral	4,61	neutral	-0,6	neutral	-1,86	low_impact	1,27	neutral	0,86	neutral	0,92	deleterious	2,89	21,8	0,45	0,55	disease	0,59	neutral	0,27	neutral	0,26	disease	0,57	1	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,67	low_impact	-3,54	medium_impact	0,28	medium_impact	-0,08	0,3	0,8	2,88	7,74	N	0,33	N	0,63	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5136	5136	T	G	MI.14172	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	667	223	S	A	Tcc/Gcc	-5,27	0	0	probably_damaging	1	neutral	0,71	neutral	4,63	neutral	-0,25	neutral	-2,35	low_impact	1,82	neutral	0,89	neutral	0,91	deleterious	2,74	21	0,38	0,5	disease	0,58	neutral	0,28	neutral	0,42	disease	0,56	1	deleterious	0,99	neutral	0,36	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	0,42	medium_impact	0,39	0,17	0,8	2,88	7,74	N	0,32	N	0,44	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5137	5137	C	A	MI.14173	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	668	223	S	Y	tCc/tAc	-0,89	0	0	probably_damaging	1	neutral	1	neutral	4,78	neutral	1,41	deleterious	-4,82	medium_impact	2,83	neutral	0,91	neutral	0,66	deleterious	4,12	23,8	0,18	0,45	disease	0,76	disease	0,63	disease	0,51	disease	0,56	1	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,75	low_impact	-3,54	high_impact	1,87	medium_impact	1,24	0,11	0,8	2,88	7,74	N	0,29	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5137	5137	C	T	MI.14174	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	668	223	S	F	tCc/tTc	-0,89	0	0	probably_damaging	1	neutral	0,74	neutral	4,62	neutral	-0,48	deleterious	-4,9	medium_impact	2,83	neutral	0,89	damaging	0,22	deleterious	4,32	24	0,21	0,45	disease	0,82	disease	0,71	disease	0,59	disease	0,72	4	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	0,46	medium_impact	1,24	0,06	0,8	2,88	7,74	N	0,27	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5137	5137	C	G	MI.14175	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	668	223	S	C	tCc/tGc	-0,89	0	0	probably_damaging	1	neutral	0,19	neutral	4,59	neutral	-1,13	deleterious	-3,85	medium_impact	3,17	neutral	0,86	damaging	0,13	deleterious	3,65	23,2	0,19	0,45	disease	0,91	disease	0,68	disease	0,54	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,14	medium_impact	1,52	0,12	0,8	2,88	7,74	N	0,33	N	0,56	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5139	5139	A	G	MI.14176	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	670	224	S	G	Agc/Ggc	-11,25	0	0	benign	0,34	neutral	0,49	neutral	4,47	neutral	-2,76	deleterious	-2,7	medium_impact	2	neutral	0,87	neutral	0,49	deleterious	3,64	23,2	0,29	0,45	disease	0,76	neutral	0,47	disease	0,59	disease	0,67	3	neutral	0,43	deleterious	0,58	neutral	-3	deleterious	0,44	medium_impact	-0,53	medium_impact	0,2	medium_impact	0,54	0,28	0,8	4,32	8,06	N	0,3	N	0,33	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5139	5139	A	T	MI.14177	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	670	224	S	C	Agc/Tgc	-11,25	0	0	probably_damaging	0,95	neutral	0,27	neutral	4,44	deleterious	-4,64	deleterious	-3,54	medium_impact	2,35	neutral	0,8	neutral	0,39	deleterious	3,53	23,1	0,13	0,4	disease	0,87	disease	0,69	disease	0,59	disease	0,69	4	neutral	0,96	neutral	0,16	deleterious	1	deleterious	0,73	low_impact	-1,97	medium_impact	-0,03	medium_impact	0,83	0,15	0,8	4,32	8,06	N	0,29	N	0,54	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5139	5139	A	C	MI.14178	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	670	224	S	R	Agc/Cgc	-11,25	0	0	possibly_damaging	0,62	neutral	0,36	neutral	4,49	neutral	-1,99	deleterious	-2,82	medium_impact	2,69	neutral	0,86	neutral	0,4	deleterious	3,9	23,5	0,12	0,4	disease	0,79	disease	0,75	disease	0,66	disease	0,71	4	neutral	0,68	neutral	0,37	NA	0	deleterious	0,63	medium_impact	-0,99	medium_impact	0,07	medium_impact	1,12	0,34	0,8	4,32	8,06	N	0,28	N	0,71	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5140	5140	G	A	MI.14179	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	671	224	S	N	aGc/aAc	-2,04	0	0	benign	0,01	neutral	0,84	neutral	4,5	neutral	-1,75	neutral	-0,78	low_impact	1,88	neutral	0,92	neutral	0,83	deleterious	2	16,21	0,52	0,6	disease	0,8	disease	0,51	neutral	0,38	neutral	0,38	2	neutral	0,12	deleterious	0,92	neutral	-6	neutral	0,21	medium_impact	1,03	medium_impact	0,61	medium_impact	0,44	0,34	0,8	4,32	8,06	N	0,24	N	0,23	polymorphism	1	0,01	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	9194	9194	A	G	MI.1418	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	668	223	H	R	cAc/cGc	4,52	1	0	probably_damaging	0,99	neutral	0,13	neutral	4,42	neutral	0,86	deleterious	-3,91	neutral_impact	0,3	neutral	0,93	neutral	0,54	deleterious	3,27	22,8	0,73	0,8	NA	NA	neutral	0,45	neutral	0,43	neutral	0,22	6	deleterious	0,99	neutral	0,07	neutral	-2	deleterious	0,78	low_impact	-2,65	medium_impact	-0,18	medium_impact	-0,84	0,4	0,9	NA	NA	N	0,48	N	0,43	disease_causing	0,87	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5140	5140	G	T	MI.14180	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	671	224	S	I	aGc/aTc	-2,04	0	0	possibly_damaging	0,86	neutral	0,66	neutral	4,49	neutral	-2,08	deleterious	-3,99	neutral_impact	0,12	neutral	0,91	neutral	0,87	deleterious	2,89	21,8	0,15	0,45	disease	0,53	disease	0,67	neutral	0,4	neutral	0,25	5	neutral	0,83	neutral	0,4	neutral	-3	deleterious	0,68	low_impact	-1,52	medium_impact	0,37	low_impact	-1,04	0,22	0,8	4,32	8,06	N	0,27	N	0,81	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5140	5140	G	C	MI.14181	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	671	224	S	T	aGc/aCc	-2,04	0	0	benign	0,42	neutral	0,96	neutral	4,63	neutral	-0,09	neutral	-0,81	neutral_impact	-0,46	neutral	0,9	neutral	0,98	neutral	1,25	11,99	0,32	0,5	neutral	0,48	neutral	0,11	neutral	0,25	neutral	0,29	4	neutral	0,37	deleterious	0,77	neutral	-6	deleterious	0,46	medium_impact	-0,67	medium_impact	0,98	low_impact	-1,53	0,34	0,8	4,32	8,06	N	0,33	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5142	5142	A	G	MI.14182	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	673	225	T	A	Acc/Gcc	-14,47	0	0	benign	0,33	neutral	0,77	neutral	4,63	neutral	-0,27	deleterious	-4,44	medium_impact	2,52	neutral	0,89	neutral	0,6	deleterious	1,86	15,37	0,38	0,5	disease	0,51	neutral	0,46	disease	0,56	neutral	0,5	0	neutral	0,22	deleterious	0,72	neutral	-3	neutral	0,4	medium_impact	-0,52	medium_impact	0,5	medium_impact	0,98	0,13	0,8	0,29	6,79	N	0,3	N	0,71	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5142	5142	A	C	MI.14183	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	673	225	T	P	Acc/Ccc	-14,47	0	0	probably_damaging	0,92	neutral	0,3	neutral	4,57	neutral	-2,02	deleterious	-5,46	medium_impact	2,23	neutral	0,8	neutral	0,52	deleterious	3,53	23,1	0,08	0,35	disease	0,89	disease	0,82	disease	0,7	disease	0,69	4	neutral	0,93	neutral	0,19	deleterious	1	deleterious	0,78	low_impact	-1,77	medium_impact	0	medium_impact	0,73	0,33	0,8	0,29	6,79	N	0,28	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5142	5142	A	T	MI.14184	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	673	225	T	S	Acc/Tcc	-14,47	0	0	possibly_damaging	0,61	neutral	0,75	neutral	4,66	neutral	0,19	deleterious	-3,5	low_impact	1,45	neutral	0,85	neutral	0,75	neutral	1,8	14,98	0,46	0,55	disease	0,64	neutral	0,47	neutral	0,43	disease	0,53	1	neutral	0,52	deleterious	0,57	neutral	-3	deleterious	0,59	medium_impact	-0,98	medium_impact	0,47	medium_impact	0,08	0,33	0,8	0,29	6,79	N	0,25	N	0,4	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5143	5143	C	G	MI.14185	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	674	225	T	S	aCc/aGc	1,41	0	0	possibly_damaging	0,61	neutral	0,75	neutral	4,66	neutral	0,19	deleterious	-3,5	low_impact	1,45	neutral	0,85	neutral	0,75	deleterious	1,94	15,82	0,46	0,55	disease	0,64	neutral	0,47	neutral	0,43	disease	0,53	1	neutral	0,52	deleterious	0,57	neutral	-3	deleterious	0,59	medium_impact	-0,98	medium_impact	0,47	medium_impact	0,08	0,33	0,8	0,29	6,79	N	0,26	N	0,4	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5143	5143	C	T	MI.14186	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	674	225	T	I	aCc/aTc	1,41	0	0	benign	0,22	neutral	0,5	neutral	4,57	neutral	-2,15	deleterious	-5,3	medium_impact	2,36	neutral	0,84	neutral	0,57	deleterious	2,23	17,74	0,22	0,45	neutral	0,43	disease	0,66	disease	0,51	neutral	0,31	4	neutral	0,4	deleterious	0,64	neutral	-3	deleterious	0,43	medium_impact	-0,29	medium_impact	0,21	medium_impact	0,84	0,2	0,8	0,29	6,79	N	0,28	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5143	5143	C	A	MI.14187	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	674	225	T	N	aCc/aAc	1,41	0	0	possibly_damaging	0,9	neutral	0,56	neutral	4,65	neutral	0,16	deleterious	-4,52	low_impact	1,5	neutral	0,89	neutral	0,61	deleterious	3,64	23,2	0,41	0,5	disease	0,87	disease	0,66	neutral	0,5	neutral	0,5	0	neutral	0,88	neutral	0,33	neutral	-3	deleterious	0,73	low_impact	-1,67	medium_impact	0,27	medium_impact	0,12	0,34	0,8	0,29	6,79	N	0,32	N	0,85	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5145	5145	A	C	MI.14188	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	676	226	T	P	Acg/Ccg	-11,48	0	0	probably_damaging	1	neutral	0,2	neutral	4,53	neutral	-2,61	deleterious	-5,14	medium_impact	2,64	neutral	0,71	damaging	0,08	deleterious	3,55	23,1	0,07	0,35	disease	0,92	disease	0,83	disease	0,75	disease	0,82	6	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,13	medium_impact	1,08	0,34	0,8	2,02	7,29	N	0,25	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5145	5145	A	T	MI.14189	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	676	226	T	S	Acg/Tcg	-11,48	0	0	probably_damaging	1	neutral	0,41	neutral	4,65	neutral	0,11	deleterious	-2,85	neutral_impact	0,4	neutral	0,88	neutral	0,9	deleterious	1,98	16,08	0,47	0,55	disease	0,56	neutral	0,39	neutral	0,3	disease	0,61	2	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,12	medium_impact	-0,81	0,44	0,8	2,02	7,29	N	0,36	N	0,65	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9194	9194	A	C	MI.1419	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	668	223	H	P	cAc/cCc	4,52	1	0	probably_damaging	0,99	neutral	0,07	neutral	4,37	neutral	-0,77	deleterious	-5,74	low_impact	1,5	neutral	0,74	neutral	0,31	deleterious	3,6	23,2	0,24	0,65	NA	NA	disease	0,67	disease	0,65	disease	0,73	5	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,82	low_impact	-2,65	medium_impact	-0,34	medium_impact	0,19	0,48	0,9	NA	NA	N	0,4	N	0,99	disease_causing	0,97	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5145	5145	A	G	MI.14190	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	676	226	T	A	Acg/Gcg	-11,48	0	0	probably_damaging	1	neutral	0,51	neutral	4,59	neutral	-0,83	deleterious	-4,1	medium_impact	3,19	neutral	0,86	damaging	0,25	deleterious	3,5	23,1	0,34	0,5	disease	0,58	neutral	0,42	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	0,22	medium_impact	1,54	0,33	0,8	2,02	7,29	N	0,28	N	0,8	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5146	5146	C	A	MI.14191	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	677	226	T	K	aCg/aAg	1,87	0,01	0	probably_damaging	1	neutral	0,31	neutral	4,61	neutral	-0,47	deleterious	-4,97	neutral_impact	0,69	neutral	0,9	neutral	0,75	deleterious	2,86	21,7	0,12	0,4	disease	0,8	neutral	0,18	neutral	0,36	neutral	0,4	2	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	0,02	medium_impact	-0,56	0,35	0,8	2,02	7,29	N	0,49	N	0,72	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5146	5146	C	T	MI.14192	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	677	226	T	M	aCg/aTg	1,87	0,01	0	probably_damaging	1	neutral	0,22	neutral	4,54	neutral	-2	deleterious	-5,14	medium_impact	2,38	neutral	0,84	damaging	0,11	deleterious	4,14	23,8	0,17	0,45	disease	0,81	disease	0,58	disease	0,64	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	-0,1	medium_impact	0,86	0,41	0,8	2,02	7,29	N	0,3	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5148	5148	A	G	MI.14193	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	679	227	T	A	Acc/Gcc	-6,42	0	0	benign	0,06	neutral	0,64	neutral	4,61	neutral	-0,51	deleterious	-3,97	medium_impact	2,08	neutral	0,94	neutral	0,67	neutral	1,29	12,21	0,21	0,45	disease	0,63	neutral	0,26	disease	0,54	disease	0,57	1	neutral	0,29	deleterious	0,79	neutral	-3	neutral	0,18	medium_impact	0,3	medium_impact	0,35	medium_impact	0,61	0,22	0,8	2,02	8,1	N	0,3	N	0,42	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5148	5148	A	T	MI.14194	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	679	227	T	S	Acc/Tcc	-6,42	0	0	possibly_damaging	0,56	neutral	0,65	neutral	4,59	neutral	-1,21	deleterious	-3,23	low_impact	1,8	neutral	0,86	neutral	0,59	deleterious	3,48	23,1	0,28	0,45	disease	0,51	neutral	0,34	disease	0,51	neutral	0,39	2	neutral	0,48	deleterious	0,55	neutral	-3	deleterious	0,6	medium_impact	-0,89	medium_impact	0,36	medium_impact	0,37	0,47	0,8	2,02	8,1	N	0,25	N	0,37	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5148	5148	A	C	MI.14195	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	679	227	T	P	Acc/Ccc	-6,42	0	0	probably_damaging	0,93	neutral	0,25	neutral	4,56	neutral	-2,76	deleterious	-5,17	medium_impact	2,42	neutral	0,78	neutral	0,34	deleterious	3,91	23,5	0,05	0,35	disease	0,83	disease	0,75	disease	0,66	disease	0,75	5	neutral	0,95	neutral	0,16	deleterious	1	deleterious	0,8	low_impact	-1,83	medium_impact	-0,06	medium_impact	0,89	0,34	0,8	2,02	8,1	N	0,25	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5149	5149	C	A	MI.14196	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	680	227	T	N	aCc/aAc	3,02	0,04	0	probably_damaging	0,9	neutral	0,55	neutral	4,56	neutral	-2,4	deleterious	-4,36	medium_impact	2,08	neutral	0,85	neutral	0,64	deleterious	3,56	23,1	0,18	0,45	disease	0,87	disease	0,51	disease	0,53	disease	0,63	3	neutral	0,89	neutral	0,33	deleterious	1	deleterious	0,75	low_impact	-1,67	medium_impact	0,26	medium_impact	0,61	0,37	0,8	2,02	8,1	N	0,27	N	0,8	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5149	5149	C	G	MI.14197	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	680	227	T	S	aCc/aGc	3,02	0,04	0	possibly_damaging	0,56	neutral	0,65	neutral	4,59	neutral	-1,21	deleterious	-3,23	low_impact	1,8	neutral	0,86	neutral	0,59	deleterious	3,13	22,6	0,28	0,45	disease	0,51	neutral	0,34	disease	0,51	neutral	0,39	2	neutral	0,48	deleterious	0,55	neutral	-3	deleterious	0,6	medium_impact	-0,89	medium_impact	0,36	medium_impact	0,37	0,47	0,8	2,02	8,1	N	0,29	N	0,37	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5149	5149	C	T	MI.14198	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	680	227	T	I	aCc/aTc	3,02	0,04	0	benign	0,08	neutral	0,62	neutral	4,88	neutral	1,83	deleterious	-4,67	neutral_impact	-0,15	neutral	0,96	neutral	0,93	deleterious	-0,06	2,01	0,11	0,4	neutral	0,45	neutral	0,11	neutral	0,18	neutral	0,27	5	neutral	0,29	deleterious	0,77	neutral	-6	neutral	0,2	medium_impact	0,17	medium_impact	0,33	low_impact	-1,27	0,34	0,8	2,02	8,1	N	0,43	N	0,1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5151	5151	C	G	MI.14199	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	682	228	L	V	Cta/Gta	-6,42	0	0	probably_damaging	1	neutral	0,5	neutral	4,62	neutral	-0,32	neutral	-2,48	low_impact	1,74	neutral	0,9	damaging	0,19	deleterious	1,92	15,72	0,39	0,5	disease	0,75	neutral	0,21	neutral	0,26	disease	0,53	1	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	0,21	medium_impact	0,32	0,38	0,8	6,63	8,81	N	0,32	N	0,38	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8593	8593	A	T	MI.142	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	67	23	I	F	Atc/Ttc	-8,2	0	0	possibly_damaging	0,68	neutral	0,27	neutral	4,31	neutral	-1,25	deleterious	-2,51	low_impact	0,94	neutral	0,9	neutral	0,56	deleterious	3,31	22,9	0,39	0,65	neutral	0,48	disease	0,63	disease	0,55	disease	0,65	3	neutral	0,78	neutral	0,3	neutral	-3	deleterious	0,63	low_impact	-1,07	medium_impact	0,05	medium_impact	-0,29	0,58	0,9	19,03	10,37	N	0,37	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9194	9194	A	T	MI.1420	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	668	223	H	L	cAc/cTc	4,52	1	0	probably_damaging	0,99	neutral	0,08	neutral	4,39	neutral	-0,22	deleterious	-6,52	neutral_impact	0,34	neutral	0,85	neutral	0,42	deleterious	4,2	23,9	0,37	0,65	NA	NA	neutral	0,45	disease	0,52	neutral	0,37	3	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,75	low_impact	-2,65	medium_impact	-0,31	medium_impact	-0,81	0,4	0,9	NA	NA	N	0,42	N	0,96	disease_causing	0,97	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5151	5151	C	A	MI.14200	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	682	228	L	M	Cta/Ata	-6,42	0	0	probably_damaging	1	neutral	0,23	neutral	4,57	neutral	-1,56	neutral	-1,64	low_impact	1,53	neutral	0,87	damaging	0,25	deleterious	2,59	20,1	0,31	0,45	disease	0,84	neutral	0,23	neutral	0,14	disease	0,56	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	-0,08	medium_impact	0,14	0,48	0,8	6,63	8,81	N	0,45	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5152	5152	T	C	MI.14201	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	683	228	L	P	cTa/cCa	-1,35	0	0	probably_damaging	1	neutral	0,21	neutral	4,55	neutral	-2,47	deleterious	-5,89	low_impact	1,43	neutral	0,79	damaging	0,21	deleterious	2,56	19,88	0,06	0,35	disease	0,96	disease	0,7	neutral	0,46	disease	0,78	6	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,85	low_impact	-3,54	medium_impact	-0,11	medium_impact	0,06	0,18	0,8	6,63	8,81	N	0,27	N	0,88	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5152	5152	T	A	MI.14202	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	683	228	L	Q	cTa/cAa	-1,35	0	0	probably_damaging	1	neutral	0,29	neutral	4,63	neutral	-0,19	deleterious	-4,99	neutral_impact	0,49	neutral	0,88	damaging	0,26	deleterious	2,29	18,09	0,17	0,45	disease	0,95	neutral	0,46	neutral	0,15	disease	0,68	4	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,79	low_impact	-3,54	medium_impact	-0,01	medium_impact	-0,73	0,21	0,8	6,63	8,81	N	0,39	N	0,73	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5152	5152	T	G	MI.14203	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	683	228	L	R	cTa/cGa	-1,35	0	0	probably_damaging	1	neutral	0,34	neutral	4,72	neutral	0,79	deleterious	-5,02	low_impact	1,48	neutral	0,9	damaging	0,13	deleterious	2,21	17,54	0,12	0,4	disease	0,95	disease	0,66	neutral	0,34	disease	0,79	6	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,81	low_impact	-3,54	medium_impact	0,05	medium_impact	0,1	0,2	0,8	6,63	8,81	N	0,35	N	0,68	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5154	5154	C	A	MI.14204	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	685	229	L	M	Cta/Ata	-6,19	0	0	benign	0,02	neutral	0,31	neutral	4,58	neutral	-1,91	neutral	0,87	neutral_impact	-1,13	neutral	0,96	neutral	0,88	deleterious	0,84	9,68	0,29	0,45	disease	0,74	neutral	0,11	neutral	0,15	neutral	0,45	1	neutral	0,68	deleterious	0,65	neutral	-6	neutral	0,17	medium_impact	0,75	medium_impact	0,02	low_impact	-2,1	0,42	0,8	1,73	7,38	N	0,53	P	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5154	5154	C	G	MI.14205	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	685	229	L	V	Cta/Gta	-6,19	0	0	benign	0,14	neutral	0,53	neutral	4,61	neutral	-0,88	neutral	-0,02	neutral_impact	0,11	neutral	0,89	neutral	0,72	deleterious	1,87	15,38	0,31	0,45	disease	0,73	neutral	0,12	neutral	0,43	neutral	0,4	2	neutral	0,37	deleterious	0,7	neutral	-6	neutral	0,31	medium_impact	-0,08	medium_impact	0,24	low_impact	-1,05	0,32	0,8	1,73	7,38	N	0,37	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5155	5155	T	G	MI.14206	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	686	229	L	R	cTa/cGa	-2,04	0	0	possibly_damaging	0,46	neutral	0,34	neutral	4,61	neutral	0,64	neutral	0,04	neutral_impact	0	neutral	0,84	neutral	0,47	deleterious	4,14	23,8	0,12	0,4	disease	0,87	disease	0,54	neutral	0,43	disease	0,61	2	neutral	0,62	neutral	0,44	neutral	-3	deleterious	0,65	medium_impact	-0,73	medium_impact	0,05	low_impact	-1,14	0,15	0,8	1,73	7,38	N	0,34	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5155	5155	T	C	MI.14207	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	686	229	L	P	cTa/cCa	-2,04	0	0	possibly_damaging	0,55	neutral	0,23	neutral	4,56	neutral	-2,37	neutral	-0,11	neutral_impact	0,26	neutral	0,78	neutral	0,74	deleterious	3,92	23,5	0,08	0,35	disease	0,96	disease	0,67	disease	0,62	disease	0,84	7	neutral	0,76	neutral	0,34	neutral	-3	deleterious	0,78	medium_impact	-0,88	medium_impact	-0,08	medium_impact	-0,93	0,19	0,8	1,73	7,38	N	0,36	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5155	5155	T	A	MI.14208	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	686	229	L	Q	cTa/cAa	-2,04	0	0	possibly_damaging	0,46	neutral	0,33	neutral	4,6	neutral	-0,13	neutral	0,76	neutral_impact	-1,7	neutral	0,9	neutral	0,66	deleterious	4,21	23,9	0,18	0,45	disease	0,95	neutral	0,42	neutral	0,33	disease	0,67	3	neutral	0,63	neutral	0,44	neutral	-3	deleterious	0,7	medium_impact	-0,73	medium_impact	0,04	low_impact	-2,58	0,15	0,8	1,73	7,38	N	0,46	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5157	5157	C	G	MI.14209	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	688	230	L	V	Cta/Gta	-4,58	0	0	possibly_damaging	0,87	neutral	0,52	neutral	4,46	neutral	-1,37	deleterious	-2,84	medium_impact	2,44	neutral	0,86	damaging	0,17	deleterious	3,49	23,1	0,21	0,45	disease	0,79	neutral	0,29	disease	0,68	disease	0,62	2	neutral	0,86	neutral	0,33	NA	0	deleterious	0,71	low_impact	-1,55	medium_impact	0,23	medium_impact	0,91	0,41	0,8	0,58	7,05	N	0,26	N	0,6	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9195	9195	C	A	MI.1421	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	669	223	H	Q	caC/caA	5,68	1	0	probably_damaging	0,99	neutral	1	neutral	4,47	neutral	1,54	deleterious	-2,78	neutral_impact	-1,94	neutral	0,87	neutral	0,85	neutral	1,47	13,13	0,78	0,8	NA	NA	neutral	0,03	neutral	0,24	neutral	0,19	6	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,68	low_impact	-2,65	high_impact	1,98	low_impact	-2,76	0,53	0,9	NA	NA	N	0,48	N	0,77	disease_causing	0,68	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5157	5157	C	A	MI.14210	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	688	230	L	M	Cta/Ata	-4,58	0	0	possibly_damaging	0,71	neutral	0,39	neutral	4,48	neutral	-1,18	neutral	-1,88	low_impact	1,56	neutral	0,89	neutral	0,45	deleterious	2,75	21,1	0,23	0,45	disease	0,87	neutral	0,12	neutral	0,27	neutral	0,44	1	neutral	0,73	neutral	0,34	neutral	-3	deleterious	0,66	low_impact	-1,15	medium_impact	0,1	medium_impact	0,17	0,42	0,8	0,58	7,05	N	0,42	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5158	5158	T	A	MI.14211	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	689	230	L	Q	cTa/cAa	-0,89	0	0	probably_damaging	0,99	neutral	0,28	neutral	4,36	deleterious	-3,79	deleterious	-5,62	medium_impact	3,06	neutral	0,82	damaging	0,12	deleterious	4,32	24	0,02	0,35	disease	0,9	disease	0,71	disease	0,67	disease	0,7	4	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,8	low_impact	-2,62	medium_impact	-0,02	medium_impact	1,43	0,21	0,8	0,58	7,05	N	0,27	N	0,94	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5158	5158	T	C	MI.14212	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	689	230	L	P	cTa/cCa	-0,89	0	0	probably_damaging	0,99	neutral	0,26	neutral	4,35	deleterious	-4,39	deleterious	-6,54	medium_impact	3,21	neutral	0,76	damaging	0,1	deleterious	4,06	23,7	0,02	0,35	disease	0,94	disease	0,74	disease	0,8	disease	0,8	6	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,86	low_impact	-2,62	medium_impact	-0,04	medium_impact	1,56	0,15	0,8	0,58	7,05	N	0,33	N	0,88	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5158	5158	T	G	MI.14213	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	689	230	L	R	cTa/cGa	-0,89	0	0	probably_damaging	0,99	neutral	0,34	neutral	4,36	deleterious	-3,69	deleterious	-5,62	high_impact	3,76	neutral	0,75	damaging	0,1	deleterious	4,22	23,9	0,01	0,35	disease	0,9	disease	0,72	disease	0,8	disease	0,76	5	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-2,62	medium_impact	0,05	high_impact	2,02	0,17	0,8	0,58	7,05	N	0,37	N	0,95	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5160	5160	T	C	MI.14214	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	691	231	S	P	Tct/Cct	-1,35	0	0	probably_damaging	0,9	neutral	0,21	neutral	4,54	neutral	-2,52	deleterious	-4,39	low_impact	1,71	neutral	0,8	neutral	0,36	deleterious	3,8	23,4	0,09	0,35	disease	0,97	disease	0,78	disease	0,74	disease	0,74	5	neutral	0,94	neutral	0,16	neutral	-2	deleterious	0,84	low_impact	-1,67	medium_impact	-0,11	medium_impact	0,3	0,16	0,8	0,29	9,24	N	0,28	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5160	5160	T	G	MI.14215	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	691	231	S	A	Tct/Gct	-1,35	0	0	benign	0,06	neutral	0,54	neutral	4,62	neutral	-0,24	neutral	-2,14	neutral_impact	0,7	neutral	0,92	neutral	0,94	deleterious	0,59	8,12	0,38	0,5	neutral	0,44	neutral	0,12	neutral	0,22	neutral	0,3	4	neutral	0,4	deleterious	0,74	neutral	-6	neutral	0,16	medium_impact	0,3	medium_impact	0,25	medium_impact	-0,56	0,27	0,8	0,29	9,24	N	0,36	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5160	5160	T	A	MI.14216	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	691	231	S	T	Tct/Act	-1,35	0	0	benign	0,1	neutral	0,43	neutral	4,57	neutral	-1,12	deleterious	-2,52	low_impact	0,88	neutral	0,93	neutral	0,91	deleterious	0,73	9,04	0,31	0,5	disease	0,85	neutral	0,19	neutral	0,22	disease	0,53	1	neutral	0,51	deleterious	0,67	neutral	-6	neutral	0,22	medium_impact	0,08	medium_impact	0,14	medium_impact	-0,4	0,36	0,8	0,29	9,24	N	0,4	N	0,15	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5161	5161	C	A	MI.14217	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	692	231	S	Y	tCt/tAt	-0,66	0	0	probably_damaging	0,95	neutral	1	neutral	4,53	deleterious	-3,01	deleterious	-5,35	low_impact	1,78	neutral	0,91	neutral	0,42	deleterious	4,11	23,7	0,1	0,4	disease	0,99	disease	0,62	disease	0,64	disease	0,81	6	neutral	0,95	deleterious	0,53	neutral	-2	deleterious	0,81	low_impact	-1,97	high_impact	1,87	medium_impact	0,35	0,17	0,8	0,29	9,24	N	0,25	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5161	5161	C	G	MI.14218	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	692	231	S	C	tCt/tGt	-0,66	0	0	probably_damaging	0,97	neutral	0,17	neutral	4,52	deleterious	-4,4	deleterious	-4,27	medium_impact	3,1	neutral	0,8	neutral	0,39	deleterious	3,53	23,1	0,12	0,4	disease	0,98	disease	0,63	disease	0,58	disease	0,8	6	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,79	low_impact	-2,18	medium_impact	-0,17	medium_impact	1,47	0,24	0,8	0,29	9,24	N	0,35	N	0,76	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5161	5161	C	T	MI.14219	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	692	231	S	F	tCt/tTt	-0,66	0	0	probably_damaging	0,93	neutral	0,72	neutral	4,55	neutral	-2,07	deleterious	-5,34	low_impact	1,21	neutral	0,89	neutral	0,42	deleterious	4,1	23,7	0,13	0,4	disease	0,99	disease	0,62	disease	0,65	disease	0,81	6	neutral	0,92	neutral	0,4	neutral	-2	deleterious	0,8	low_impact	-1,83	medium_impact	0,44	medium_impact	-0,13	0,05	0,8	0,29	9,24	N	0,29	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9195	9195	C	G	MI.1422	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	669	223	H	Q	caC/caG	5,68	1	0	probably_damaging	0,99	neutral	1	neutral	4,47	neutral	1,54	deleterious	-2,78	neutral_impact	-1,94	neutral	0,87	neutral	0,85	neutral	1,14	11,42	0,78	0,8	NA	NA	neutral	0,03	neutral	0,24	neutral	0,19	6	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,68	low_impact	-2,65	high_impact	1,98	low_impact	-2,76	0,53	0,9	NA	NA	N	0,48	N	0,77	disease_causing	0,68	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5163	5163	C	G	MI.14220	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	694	232	R	G	Cgc/Ggc	-9,18	0	0	benign	0,19	neutral	0,35	neutral	4,9	neutral	0,03	neutral	-2,17	neutral_impact	-0,34	neutral	0,9	neutral	0,64	deleterious	2,76	21,1	0,1	0,4	disease	0,59	neutral	0,24	neutral	0,42	disease	0,53	1	neutral	0,58	deleterious	0,58	neutral	-6	neutral	0,4	medium_impact	-0,22	medium_impact	0,06	low_impact	-1,43	0,19	0,8	13,54	8,77	N	0,37	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5163	5163	C	T	MI.14221	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	694	232	R	C	Cgc/Tgc	-9,18	0	0	possibly_damaging	0,89	neutral	0,18	neutral	4,55	deleterious	-5,97	deleterious	-2,7	neutral_impact	-0,14	neutral	0,83	neutral	0,28	deleterious	3,83	23,4	0,1	0,4	disease	0,86	neutral	0,44	neutral	0,36	disease	0,68	4	neutral	0,94	neutral	0,15	neutral	-3	deleterious	0,72	low_impact	-1,63	medium_impact	-0,16	low_impact	-1,26	0,76	0,85	13,54	8,77	N	0,32	N	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5163	5163	C	A	MI.14222	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	694	232	R	S	Cgc/Agc	-9,18	0	0	benign	0,19	neutral	0,51	neutral	4,72	neutral	-1,66	neutral	-0,91	neutral_impact	-1,5	neutral	0,82	neutral	0,75	deleterious	2,91	21,9	0,14	0,4	disease	0,63	neutral	0,17	neutral	0,21	neutral	0,44	1	neutral	0,39	deleterious	0,66	neutral	-6	neutral	0,35	medium_impact	-0,22	medium_impact	0,22	low_impact	-2,41	0,26	0,8	13,54	8,77	N	0,35	N	0,58	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5164	5164	G	C	MI.14223	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	695	232	R	P	cGc/cCc	0,03	0	0	possibly_damaging	0,72	neutral	0,23	neutral	4,57	deleterious	-3,79	neutral	-2,19	neutral_impact	0,2	neutral	0,74	neutral	0,28	deleterious	2,96	22,1	0,04	0,35	disease	0,63	disease	0,62	disease	0,53	disease	0,6	2	neutral	0,83	neutral	0,26	neutral	-3	deleterious	0,73	low_impact	-1,17	medium_impact	-0,08	medium_impact	-0,98	0,13	0,8	13,54	8,77	N	0,29	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5164	5164	G	A	MI.14224	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	695	232	R	H	cGc/cAc	0,03	0	0	benign	0,01	neutral	0,54	neutral	4,58	deleterious	-3,01	neutral	2,76	neutral_impact	-1,12	neutral	0,9	neutral	0,94	deleterious	1,81	15,04	0,23	0,45	neutral	0,45	neutral	0,1	neutral	0,11	neutral	0,31	4	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	0,25	low_impact	-2,09	0,68	0,85	13,54	8,77	N	0,37	N	0,23	polymorphism	1	0,01	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	5164	5164	G	T	MI.14225	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	695	232	R	L	cGc/cTc	0,03	0	0	benign	0,01	neutral	0,75	neutral	4,59	deleterious	-3,11	neutral	-1,87	neutral_impact	-1,64	neutral	0,9	neutral	0,91	deleterious	1,85	15,29	0,1	0,4	neutral	0,46	neutral	0,28	neutral	0,15	neutral	0,44	1	neutral	0,22	deleterious	0,87	neutral	-6	neutral	0,15	medium_impact	1,03	medium_impact	0,47	low_impact	-2,53	0,06	0,8	13,54	8,77	N	0,36	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5166	5166	A	T	MI.14226	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	697	233	T	S	Acc/Tcc	-11,48	0	0	benign	0,04	neutral	0,42	neutral	4,61	neutral	-0,71	neutral	-1,46	neutral_impact	0,7	neutral	0,93	neutral	0,96	neutral	-0,45	0,29	0,39	0,5	disease	0,79	neutral	0,05	neutral	0,23	neutral	0,37	3	neutral	0,55	deleterious	0,69	neutral	-6	neutral	0,22	medium_impact	0,47	medium_impact	0,13	medium_impact	-0,56	0,46	0,8	6,34	7,53	N	0,47	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5166	5166	A	C	MI.14227	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	697	233	T	P	Acc/Ccc	-11,48	0	0	possibly_damaging	0,81	neutral	0,21	neutral	4,56	neutral	-2,69	deleterious	-3,53	medium_impact	2,68	neutral	0,84	neutral	0,35	deleterious	0,86	9,84	0,06	0,35	disease	0,91	disease	0,69	neutral	0,5	disease	0,63	3	neutral	0,88	neutral	0,2	NA	0	deleterious	0,81	low_impact	-1,37	medium_impact	-0,11	medium_impact	1,11	0,33	0,8	6,34	7,53	N	0,33	N	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5166	5166	A	G	MI.14228	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	697	233	T	A	Acc/Gcc	-11,48	0	0	benign	0,02	neutral	0,51	neutral	4,62	neutral	-0,43	neutral	-2,03	low_impact	1,21	neutral	0,95	neutral	0,97	deleterious	0,31	5,81	0,26	0,45	disease	0,72	neutral	0,12	neutral	0,35	neutral	0,45	1	neutral	0,46	deleterious	0,75	neutral	-6	neutral	0,2	medium_impact	0,75	medium_impact	0,22	medium_impact	-0,13	0,28	0,8	6,34	7,53	N	0,37	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5167	5167	C	T	MI.14229	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	698	233	T	I	aCc/aTc	-0,89	0	0	possibly_damaging	0,81	neutral	0,4	neutral	4,66	neutral	0,27	neutral	-2,48	low_impact	1,37	neutral	0,91	neutral	0,68	neutral	1,33	12,42	0,17	0,45	disease	0,55	neutral	0,37	neutral	0,41	disease	0,58	2	neutral	0,81	neutral	0,3	neutral	-3	deleterious	0,68	low_impact	-1,37	medium_impact	0,11	medium_impact	0,01	0,36	0,8	6,34	7,53	N	0,38	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9196	9196	G	C	MI.1423	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	670	224	D	H	Gac/Cac	-0,8	0,08	0	possibly_damaging	0,8	deleterious	0	neutral	4,28	deleterious	-4,9	deleterious	-3,75	medium_impact	2,88	neutral	0,81	neutral	0,36	deleterious	3,75	23,3	0,48	0,65	NA	NA	neutral	0,23	disease	0,58	neutral	0,38	3	deleterious	1	neutral	0,1	deleterious	4	deleterious	0,62	low_impact	-1,33	low_impact	-1,4	medium_impact	1,37	0,5	0,9	NA	NA	N	0,38	N	0,89	polymorphism	0,99	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5167	5167	C	G	MI.14230	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	698	233	T	S	aCc/aGc	-0,89	0	0	benign	0,04	neutral	0,42	neutral	4,61	neutral	-0,71	neutral	-1,46	neutral_impact	0,7	neutral	0,93	neutral	0,96	neutral	-0,29	0,71	0,39	0,5	disease	0,79	neutral	0,05	neutral	0,23	neutral	0,37	3	neutral	0,55	deleterious	0,69	neutral	-6	neutral	0,22	medium_impact	0,47	medium_impact	0,13	medium_impact	-0,56	0,46	0,8	6,34	7,53	N	0,47	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5167	5167	C	A	MI.14231	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	698	233	T	N	aCc/aAc	-0,89	0	0	possibly_damaging	0,58	neutral	0,31	neutral	4,57	neutral	-2,38	deleterious	-2,79	low_impact	1,73	neutral	0,86	neutral	0,54	deleterious	0,82	9,59	0,31	0,45	disease	0,95	disease	0,51	disease	0,55	disease	0,81	6	neutral	0,7	neutral	0,37	neutral	-3	deleterious	0,75	medium_impact	-0,93	medium_impact	0,02	medium_impact	0,31	0,48	0,8	6,34	7,53	N	0,35	N	0,65	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5169	5169	T	C	MI.14232	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	700	234	W	R	Tga/Cga	-1,58	0	0	probably_damaging	1	neutral	0,34	neutral	4,71	neutral	-1,73	deleterious	-11,72	high_impact	3,75	neutral	0,92	damaging	0,13	deleterious	3,64	23,2	0,05	0,35	disease	0,81	disease	0,77	disease	0,86	disease	0,76	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	0,05	high_impact	2,01	0,11	0,8	NA	NA	N	0,52	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5169	5169	T	G	MI.14233	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	700	234	W	G	Tga/Gga	-1,58	0	0	probably_damaging	1	neutral	0,36	neutral	4,66	neutral	-0,07	deleterious	-10,53	medium_impact	2,65	neutral	0,94	damaging	0,13	deleterious	4,02	23,6	0,06	0,35	disease	0,69	disease	0,69	disease	0,84	disease	0,72	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,07	medium_impact	1,09	0,13	0,8	NA	NA	N	0,43	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5170	5170	G	C	MI.14234	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	701	234	W	S	tGa/tCa	7,4	1	0	probably_damaging	1	neutral	0,54	neutral	4,77	neutral	-1,22	deleterious	-11,26	medium_impact	1,94	neutral	0,9	neutral	0,57	deleterious	3,05	22,4	0,08	0,35	neutral	0,43	disease	0,76	disease	0,8	disease	0,59	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,25	medium_impact	0,49	0,15	0,8	NA	NA	P	0,54	P	0,94	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5170	5170	G	T	MI.14235	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	701	234	W	L	tGa/tTa	7,4	1	0	probably_damaging	1	neutral	0,99	neutral	4,81	neutral	1	deleterious	-11,01	medium_impact	2,02	neutral	0,87	damaging	0,11	deleterious	4,32	24	0,12	0,4	neutral	0,5	disease	0,71	disease	0,81	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	1,32	medium_impact	0,56	0,1	0,8	NA	NA	N	0,53	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5171	5171	A	C	MI.14236	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	702	234	W	C	tgA/tgC	4,63	1	0	probably_damaging	1	neutral	0,17	neutral	4,63	deleterious	-3,12	deleterious	-10,9	medium_impact	3,21	neutral	0,92	damaging	0,16	deleterious	4,09	23,7	0,06	0,35	disease	0,84	disease	0,77	disease	0,81	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,17	medium_impact	1,56	0,11	0,8	NA	NA	P	0,61	P	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5171	5171	A	T	MI.14237	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	702	234	W	C	tgA/tgT	4,63	1	0	probably_damaging	1	neutral	0,17	neutral	4,63	deleterious	-3,12	deleterious	-10,9	medium_impact	3,21	neutral	0,92	damaging	0,16	deleterious	4,26	23,9	0,06	0,35	disease	0,84	disease	0,77	disease	0,81	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,17	medium_impact	1,56	0,11	0,8	NA	NA	P	0,61	P	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5172	5172	A	G	MI.14238	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	703	235	N	D	Aac/Gac	1,64	1	0	probably_damaging	1	neutral	0,25	neutral	4,54	neutral	-0,82	deleterious	-4,66	medium_impact	2,79	neutral	0,89	damaging	0,15	deleterious	4	23,6	0,74	0,75	disease	0,79	neutral	0,32	neutral	0,49	disease	0,64	3	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	-0,06	medium_impact	1,2	0,32	0,8	NA	NA	P	0,58	P	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5172	5172	A	C	MI.14239	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	703	235	N	H	Aac/Cac	1,64	1	0	probably_damaging	1	neutral	0,54	neutral	4,54	neutral	-1,98	deleterious	-4,69	medium_impact	1,98	neutral	0,89	damaging	0,15	deleterious	3,27	22,8	0,5	0,6	disease	0,85	neutral	0,34	neutral	0,38	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,25	medium_impact	0,52	0,11	0,8	NA	NA	N	0,45	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9196	9196	G	T	MI.1424	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	670	224	D	Y	Gac/Tac	-0,8	0,08	0	possibly_damaging	0,89	deleterious	0	neutral	4,2	deleterious	-6,13	deleterious	-5,59	medium_impact	2,88	neutral	0,84	neutral	0,44	deleterious	4,11	23,7	0,22	0,65	NA	NA	neutral	0,4	disease	0,57	neutral	0,37	3	deleterious	1	neutral	0,06	deleterious	4	deleterious	0,71	low_impact	-1,62	low_impact	-1,4	medium_impact	1,37	0,35	0,9	NA	NA	N	0,42	N	0,98	polymorphism	0,98	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5172	5172	A	T	MI.14240	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	703	235	N	Y	Aac/Tac	1,64	1	0	probably_damaging	1	neutral	1	neutral	4,55	neutral	-2,79	deleterious	-7,46	medium_impact	2,16	neutral	0,87	damaging	0,12	deleterious	3,88	23,5	0,22	0,45	disease	0,74	neutral	0,42	neutral	0,48	disease	0,64	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,74	low_impact	-3,54	high_impact	1,87	medium_impact	0,67	0,2	0,8	NA	NA	N	0,38	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5173	5173	A	G	MI.14241	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	704	235	N	S	aAc/aGc	1,18	0,99	0	probably_damaging	1	neutral	0,5	neutral	4,57	neutral	-0,38	deleterious	-4,49	low_impact	0,84	neutral	0,83	neutral	0,47	deleterious	2,01	16,3	0,72	0,75	disease	0,68	neutral	0,13	neutral	0,29	neutral	0,44	1	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,21	medium_impact	-0,44	0,15	0,8	NA	NA	N	0,44	N	0,8	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5173	5173	A	C	MI.14242	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	704	235	N	T	aAc/aCc	1,18	0,99	0	probably_damaging	1	neutral	0,49	neutral	4,58	neutral	-1,2	deleterious	-5,42	neutral_impact	0,64	neutral	0,88	neutral	0,35	deleterious	2,23	17,7	0,49	0,55	disease	0,5	neutral	0,04	neutral	0,21	neutral	0,22	6	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,66	low_impact	-3,54	medium_impact	0,2	medium_impact	-0,61	0,2	0,8	NA	NA	N	0,46	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5173	5173	A	T	MI.14243	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	704	235	N	I	aAc/aTc	1,18	0,99	0	probably_damaging	1	neutral	0,45	neutral	4,57	neutral	-2,64	deleterious	-8,35	low_impact	1,94	neutral	0,88	damaging	0,21	deleterious	3,9	23,5	0,21	0,45	neutral	0,41	neutral	0,41	neutral	0,47	neutral	0,48	1	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,16	medium_impact	0,49	0,23	0,8	NA	NA	N	0,43	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5174	5174	C	A	MI.14244	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	705	235	N	K	aaC/aaA	3,94	0,99	0	probably_damaging	1	neutral	0,4	neutral	4,72	neutral	0,11	deleterious	-5,56	low_impact	1,64	neutral	0,84	damaging	0,1	deleterious	4,52	24,3	0,54	0,6	neutral	0,38	neutral	0,37	neutral	0,5	neutral	0,47	1	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,11	medium_impact	0,24	0,5	0,8	NA	NA	N	0,43	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5174	5174	C	G	MI.14245	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	705	235	N	K	aaC/aaG	3,94	0,99	0	probably_damaging	1	neutral	0,4	neutral	4,72	neutral	0,11	deleterious	-5,56	low_impact	1,64	neutral	0,84	damaging	0,1	deleterious	4,07	23,7	0,54	0,6	neutral	0,38	neutral	0,37	neutral	0,5	neutral	0,47	1	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,11	medium_impact	0,24	0,5	0,8	NA	NA	N	0,43	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5175	5175	A	G	MI.14246	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	706	236	K	E	Aag/Gag	-4,11	0	0	probably_damaging	1	neutral	0,34	neutral	4,58	neutral	-1,5	deleterious	-3,29	medium_impact	2,14	neutral	0,85	damaging	0,13	deleterious	3,95	23,6	0,21	0,45	disease	0,87	disease	0,75	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	0,05	medium_impact	0,66	0,5	0,8	1,73	8	N	0,26	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5175	5175	A	C	MI.14247	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	706	236	K	Q	Aag/Cag	-4,11	0	0	probably_damaging	1	neutral	0,33	neutral	4,56	neutral	-1,9	deleterious	-3,29	low_impact	1,84	neutral	0,86	damaging	0,22	deleterious	3,32	22,9	0,36	0,5	disease	0,89	disease	0,65	disease	0,53	disease	0,62	2	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,77	low_impact	-3,54	medium_impact	0,04	medium_impact	0,4	0,27	0,8	1,73	8	N	0,28	N	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5176	5176	A	T	MI.14248	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	707	236	K	M	aAg/aTg	4,4	0,55	0	probably_damaging	1	neutral	0,24	neutral	4,58	deleterious	-3,83	deleterious	-4,95	low_impact	1,9	neutral	0,94	damaging	0,23	deleterious	4,17	23,8	0,13	0,4	disease	0,85	disease	0,64	disease	0,55	disease	0,62	2	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	-0,07	medium_impact	0,46	0,14	0,8	1,73	8	N	0,5	N	0,75	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5176	5176	A	C	MI.14249	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	707	236	K	T	aAg/aCg	4,4	0,55	0	probably_damaging	1	neutral	0,43	neutral	4,62	neutral	-2,3	deleterious	-4,62	low_impact	1,35	neutral	0,93	neutral	0,74	deleterious	2,71	20,9	0,14	0,4	disease	0,59	disease	0,54	neutral	0,4	neutral	0,44	1	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	0,14	medium_impact	-0,01	0,09	0,8	1,73	8	N	0,43	N	0,91	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9196	9196	G	A	MI.1425	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	670	224	D	N	Gac/Aac	-0,8	0,08	0	benign	0,27	deleterious	0,01	neutral	4,24	deleterious	-3,3	neutral	-2,31	low_impact	1,84	neutral	0,91	neutral	0,73	neutral	1,63	14	0,7	0,75	NA	NA	neutral	0,24	neutral	0,46	neutral	0,17	7	deleterious	0,99	neutral	0,37	neutral	-2	neutral	0,35	medium_impact	-0,35	medium_impact	-0,84	medium_impact	0,48	0,61	0,9	NA	NA	P	0,54	P	0,34	polymorphism	1	0,28	rs374870159	.	.	.	.	.	COSM1155696	.	.	.	.	.	.	.	.
chrM	5177	5177	G	C	MI.14250	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	708	236	K	N	aaG/aaC	1,41	0,41	0	probably_damaging	1	neutral	0,34	neutral	4,61	neutral	-2,18	deleterious	-3,72	low_impact	1,66	neutral	0,9	neutral	0,74	deleterious	2,98	22,2	0,53	0,6	disease	0,8	disease	0,64	disease	0,54	disease	0,56	1	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,79	low_impact	-3,54	medium_impact	0,05	medium_impact	0,25	0,2	0,8	1,73	8	N	0,43	N	0,85	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5177	5177	G	T	MI.14251	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	708	236	K	N	aaG/aaT	1,41	0,41	0	probably_damaging	1	neutral	0,34	neutral	4,61	neutral	-2,18	deleterious	-3,72	low_impact	1,66	neutral	0,9	neutral	0,74	deleterious	3,1	22,5	0,53	0,6	disease	0,8	disease	0,64	disease	0,54	disease	0,56	1	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,79	low_impact	-3,54	medium_impact	0,05	medium_impact	0,25	0,2	0,8	1,73	8	N	0,43	N	0,85	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5178	5178	C	G	MI.14252	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	709	237	L	V	Cta/Gta	0,03	0	1	benign	0,3	neutral	0,51	neutral	4,6	neutral	-2,22	neutral	-0,24	neutral_impact	0,5	neutral	0,88	neutral	0,76	deleterious	2,36	18,53	0,35	0,5	disease	0,54	neutral	0,15	disease	0,6	neutral	0,3	4	neutral	0,39	deleterious	0,61	neutral	-6	deleterious	0,46	medium_impact	-0,46	medium_impact	0,22	medium_impact	-0,72	0,3	0,8	8,65	8,62	N	0,38	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5178	5178	C	A	MI.14253	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	709	237	L	M	Cta/Ata	0,03	0	1	possibly_damaging	0,9	neutral	0,25	neutral	4,67	neutral	-1,39	neutral	0,39	neutral_impact	0,14	neutral	0,99	neutral	0,83	deleterious	2,36	18,59	0,32	0,5	disease	0,64	neutral	0,1	neutral	0,4	neutral	0,43	1	neutral	0,92	neutral	0,18	neutral	-3	deleterious	0,63	low_impact	-1,67	medium_impact	-0,06	low_impact	-1,03	0,51	0,8	8,65	8,62	P	0,68	P	0,43	polymorphism	1	0	rs28357984	.	.	.	.	.	.	.	.	C5178A	Longevity,Extraversion MI/AMS protection,blood iron metabolism	+	-	Reported,haplogroup D marker	18
chrM	5179	5179	T	C	MI.14254	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	710	237	L	P	cTa/cCa	-4,35	0	0	probably_damaging	0,92	neutral	0,24	neutral	4,53	deleterious	-4,81	neutral	-1,96	neutral_impact	0,66	neutral	0,74	neutral	0,36	deleterious	3,94	23,5	0,03	0,35	disease	0,93	disease	0,7	disease	0,69	disease	0,83	7	neutral	0,94	neutral	0,16	neutral	-2	deleterious	0,81	low_impact	-1,77	medium_impact	-0,07	medium_impact	-0,59	0,12	0,8	8,65	8,62	N	0,28	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5179	5179	T	G	MI.14255	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	710	237	L	R	cTa/cGa	-4,35	0	0	possibly_damaging	0,9	neutral	0,35	neutral	4,56	neutral	-2,67	neutral	-1,4	low_impact	1,15	neutral	0,84	neutral	0,44	deleterious	3,23	22,8	0,04	0,35	disease	0,9	disease	0,58	disease	0,75	disease	0,77	5	neutral	0,9	neutral	0,23	neutral	-3	deleterious	0,77	low_impact	-1,67	medium_impact	0,06	medium_impact	-0,18	0,19	0,8	8,65	8,62	N	0,31	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5179	5179	T	A	MI.14256	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	710	237	L	Q	cTa/cAa	-4,35	0	0	possibly_damaging	0,9	neutral	0,3	neutral	4,54	deleterious	-3,85	neutral	-1,12	neutral_impact	0,73	neutral	0,87	neutral	0,52	deleterious	4,1	23,7	0,06	0,35	disease	0,91	neutral	0,38	disease	0,69	disease	0,69	4	neutral	0,91	neutral	0,2	neutral	-3	deleterious	0,74	low_impact	-1,67	medium_impact	0	medium_impact	-0,53	0,12	0,8	8,65	8,62	N	0,42	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5181	5181	A	C	MI.14257	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	712	238	T	P	Aca/Cca	-6,81	0	0	benign	0,04	neutral	0,28	neutral	5,04	neutral	3,11	neutral	5,83	neutral_impact	-1,54	neutral	0,87	neutral	0,96	deleterious	0,66	8,57	0,07	0,35	neutral	0,45	neutral	0,06	neutral	0,18	neutral	0,26	5	neutral	0,7	deleterious	0,62	neutral	-6	neutral	0,15	medium_impact	0,47	medium_impact	-0,02	low_impact	-2,44	0,29	0,8	0,58	7,2	N	0,48	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5181	5181	A	G	MI.14258	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	712	238	T	A	Aca/Gca	-6,81	0	0	benign	0,02	neutral	0,56	neutral	4,69	neutral	0,8	neutral	-0,67	low_impact	1,25	neutral	0,98	neutral	0,97	neutral	1,56	13,66	0,29	0,45	neutral	0,4	neutral	0,32	disease	0,53	neutral	0,44	1	neutral	0,41	deleterious	0,77	neutral	-6	neutral	0,18	medium_impact	0,75	medium_impact	0,27	medium_impact	-0,09	0,28	0,8	0,58	7,2	N	0,33	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5181	5181	A	T	MI.14259	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	712	238	T	S	Aca/Tca	-6,81	0	0	possibly_damaging	0,44	neutral	0,45	neutral	4,66	neutral	0,28	neutral	-0,56	neutral_impact	0,24	neutral	0,83	neutral	0,84	neutral	1,63	14,02	0,44	0,55	disease	0,63	neutral	0,36	neutral	0,36	disease	0,6	2	neutral	0,51	deleterious	0,51	neutral	-3	deleterious	0,5	medium_impact	-0,7	medium_impact	0,16	medium_impact	-0,94	0,39	0,8	0,58	7,2	N	0,33	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9197	9197	A	C	MI.1426	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	671	224	D	A	gAc/gCc	6,14	1	0	benign	0,27	deleterious	0	neutral	4,26	deleterious	-3,86	deleterious	-4,81	medium_impact	2,88	neutral	0,84	neutral	0,48	deleterious	2,21	17,6	0,38	0,65	NA	NA	neutral	0,22	disease	0,52	neutral	0,3	4	deleterious	1	neutral	0,37	deleterious	1	neutral	0,3	medium_impact	-0,35	low_impact	-1,4	medium_impact	1,37	0,54	0,9	NA	NA	P	0,61	P	0,8	disease_causing	0,5	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5182	5182	C	A	MI.14260	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	713	238	T	K	aCa/aAa	2,9	0,87	0	possibly_damaging	0,66	neutral	0,35	neutral	4,7	neutral	0,98	neutral	-0,82	neutral_impact	0,24	neutral	0,86	neutral	0,52	deleterious	3,09	22,5	0,13	0,4	disease	0,79	disease	0,61	disease	0,65	disease	0,75	5	neutral	0,71	neutral	0,35	neutral	-3	deleterious	0,73	low_impact	-1,06	medium_impact	0,06	medium_impact	-0,94	0,26	0,8	0,58	7,2	N	0,32	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5182	5182	C	T	MI.14261	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	713	238	T	M	aCa/aTa	2,9	0,87	0	possibly_damaging	0,9	neutral	0,24	neutral	4,64	neutral	-0,21	neutral	-1,62	neutral_impact	0,62	neutral	0,89	neutral	0,54	deleterious	4	23,6	0,26	0,45	disease	0,58	neutral	0,5	neutral	0,39	disease	0,5	0	neutral	0,92	neutral	0,17	neutral	-3	deleterious	0,71	low_impact	-1,67	medium_impact	-0,07	medium_impact	-0,62	0,32	0,8	0,58	7,2	N	0,43	N	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5184	5184	T	C	MI.14262	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	715	239	W	R	Tga/Cga	-11,44	0	0	possibly_damaging	0,7	neutral	0,22	neutral	4,66	neutral	1,42	neutral	-1,55	low_impact	0,9	neutral	0,87	neutral	0,46	deleterious	3,54	23,1	0,07	0,35	disease	0,66	neutral	0,21	disease	0,51	neutral	0,39	2	neutral	0,82	neutral	0,26	neutral	-3	deleterious	0,62	low_impact	-1,13	medium_impact	-0,1	medium_impact	-0,39	0,09	0,8	10,37	9,76	N	0,4	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5184	5184	T	G	MI.14263	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	715	239	W	G	Tga/Gga	-11,44	0	0	possibly_damaging	0,62	neutral	0,35	neutral	4,69	neutral	2,48	deleterious	-2,84	neutral_impact	0,2	neutral	0,89	neutral	0,49	deleterious	3,92	23,5	0,09	0,35	disease	0,62	neutral	0,13	disease	0,53	neutral	0,33	3	neutral	0,69	neutral	0,37	neutral	-3	deleterious	0,58	medium_impact	-0,99	medium_impact	0,06	medium_impact	-0,98	0,13	0,8	10,37	9,76	N	0,41	N	0,53	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5185	5185	G	T	MI.14264	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	716	239	W	L	tGa/tTa	-6,81	0	0	possibly_damaging	0,45	neutral	1	neutral	4,87	neutral	4,72	neutral	2,71	neutral_impact	-1,51	neutral	0,87	neutral	0,96	neutral	1,57	13,67	0,12	0,4	disease	0,61	neutral	0,07	neutral	0,22	neutral	0,26	5	neutral	0,45	deleterious	0,78	neutral	-3	deleterious	0,5	medium_impact	-0,72	high_impact	1,87	low_impact	-2,42	0,08	0,8	10,37	9,76	N	0,28	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5185	5185	G	C	MI.14265	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	716	239	W	S	tGa/tCa	-6,81	0	0	possibly_damaging	0,67	neutral	0,4	neutral	4,7	neutral	2,79	neutral	-1,38	neutral_impact	-1,1	neutral	0,78	neutral	0,83	deleterious	2,9	21,8	0,1	0,4	neutral	0,4	neutral	0,09	neutral	0,47	neutral	0,29	4	neutral	0,69	neutral	0,37	neutral	-3	deleterious	0,55	low_impact	-1,08	medium_impact	0,11	low_impact	-2,07	0,13	0,8	10,37	9,76	N	0,34	N	0,57	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5186	5186	A	C	MI.14266	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	717	239	W	C	tgA/tgC	-0,57	0	0,02	probably_damaging	0,95	neutral	0,11	neutral	4,65	neutral	0,9	neutral	-0,7	low_impact	0,9	neutral	0,89	neutral	0,45	deleterious	4,01	23,6	0,09	0,35	disease	0,6	neutral	0,27	neutral	0,49	neutral	0,47	1	neutral	0,98	neutral	0,08	neutral	-2	deleterious	0,67	low_impact	-1,97	medium_impact	-0,3	medium_impact	-0,39	0,11	0,8	10,37	9,76	N	0,51	P	0,57	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5186	5186	A	T	MI.14267	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	717	239	W	C	tgA/tgT	-0,57	0	0,02	probably_damaging	0,95	neutral	0,11	neutral	4,65	neutral	0,9	neutral	-0,7	low_impact	0,9	neutral	0,89	neutral	0,45	deleterious	4,15	23,8	0,09	0,35	disease	0,6	neutral	0,27	neutral	0,49	neutral	0,47	1	neutral	0,98	neutral	0,08	neutral	-2	deleterious	0,67	low_impact	-1,97	medium_impact	-0,3	medium_impact	-0,39	0,11	0,8	10,37	9,76	N	0,51	P	0,57	polymorphism	1	0,06	rs878939965	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5187	5187	C	A	MI.14268	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	718	240	L	M	Cta/Ata	-4,96	0	0	benign	0,24	neutral	0,47	neutral	4,49	neutral	-2,61	neutral	-0,24	neutral_impact	0,18	neutral	0,92	neutral	0,81	neutral	1,41	12,82	0,33	0,5	disease	0,7	neutral	0,13	neutral	0,26	neutral	0,36	3	neutral	0,43	deleterious	0,62	neutral	-6	neutral	0,36	medium_impact	-0,34	medium_impact	0,18	medium_impact	-0,99	0,64	0,8	NA	NA	N	0,43	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5187	5187	C	G	MI.14269	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	718	240	L	V	Cta/Gta	-4,96	0	0	benign	0,1	neutral	0,38	neutral	4,49	neutral	-1,57	neutral	-0,47	low_impact	1,31	neutral	0,95	neutral	0,8	deleterious	2,28	18,05	0,33	0,5	disease	0,59	neutral	0,27	disease	0,62	disease	0,57	1	neutral	0,57	deleterious	0,64	neutral	-6	neutral	0,25	medium_impact	0,08	medium_impact	0,09	medium_impact	-0,04	0,61	0,8	NA	NA	N	0,39	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9197	9197	A	G	MI.1427	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	671	224	D	G	gAc/gGc	6,14	1	0	benign	0,34	deleterious	0	neutral	4,22	deleterious	-4,17	deleterious	-4,47	medium_impact	2,52	neutral	0,8	neutral	0,46	deleterious	2,67	20,6	0,43	0,65	NA	NA	neutral	0,32	disease	0,53	neutral	0,33	3	deleterious	1	neutral	0,33	deleterious	1	neutral	0,38	medium_impact	-0,48	low_impact	-1,4	medium_impact	1,06	0,4	0,9	NA	NA	P	0,57	P	0,69	disease_causing	0,59	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5188	5188	T	C	MI.14270	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	719	240	L	P	cTa/cCa	-3,11	0	0	probably_damaging	0,96	neutral	0,2	neutral	4,39	deleterious	-5,14	deleterious	-4,45	medium_impact	2,01	neutral	0,83	neutral	0,39	deleterious	3,98	23,6	0,03	0,35	disease	0,91	disease	0,72	disease	0,75	disease	0,82	6	neutral	0,97	neutral	0,12	deleterious	1	deleterious	0,82	low_impact	-2,06	medium_impact	-0,13	medium_impact	0,55	0,1	0,8	NA	NA	N	0,31	N	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5188	5188	T	G	MI.14271	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	719	240	L	R	cTa/cGa	-3,11	0	0	probably_damaging	0,96	neutral	0,25	neutral	4,43	neutral	-2,4	deleterious	-3,93	medium_impact	2,7	neutral	0,85	neutral	0,43	deleterious	4,23	23,9	0,03	0,35	disease	0,88	disease	0,7	disease	0,75	disease	0,81	6	neutral	0,97	neutral	0,15	deleterious	1	deleterious	0,8	low_impact	-2,06	medium_impact	-0,06	medium_impact	1,13	0,09	0,8	NA	NA	N	0,32	N	0,87	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5188	5188	T	A	MI.14272	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	719	240	L	Q	cTa/cAa	-3,11	0	0	probably_damaging	0,96	neutral	0,23	neutral	4,43	deleterious	-3,97	deleterious	-3,72	low_impact	1,42	neutral	0,86	neutral	0,51	deleterious	4,24	23,9	0,05	0,35	disease	0,89	disease	0,63	disease	0,63	disease	0,71	4	neutral	0,97	neutral	0,14	neutral	-2	deleterious	0,75	low_impact	-2,06	medium_impact	-0,08	medium_impact	0,05	0,15	0,8	NA	NA	N	0,32	N	0,85	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5190	5190	A	T	MI.14273	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	721	241	T	S	Aca/Tca	-1,49	0	0	benign	0,05	neutral	0,62	neutral	4,66	neutral	0,04	neutral	-2,09	low_impact	1	neutral	0,78	neutral	0,92	deleterious	0,42	6,76	0,33	0,5	disease	0,54	neutral	0,18	neutral	0,3	neutral	0,33	3	neutral	0,31	deleterious	0,79	neutral	-6	neutral	0,19	medium_impact	0,37	medium_impact	0,33	medium_impact	-0,3	0,55	0,8	9,22	8,54	N	0,3	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5190	5190	A	C	MI.14274	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	721	241	T	P	Aca/Cca	-1,49	0	0	benign	0,29	neutral	0,25	neutral	4,56	neutral	-2,24	deleterious	-3,9	medium_impact	1,94	neutral	0,81	neutral	0,46	deleterious	3,15	22,6	0,05	0,35	disease	0,79	disease	0,74	disease	0,7	disease	0,76	5	neutral	0,7	deleterious	0,48	neutral	-3	deleterious	0,56	medium_impact	-0,44	medium_impact	-0,06	medium_impact	0,49	0,36	0,8	9,22	8,54	N	0,27	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5190	5190	A	G	MI.14275	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	721	241	T	A	Aca/Gca	-1,49	0	0	benign	0	neutral	0,64	neutral	4,8	neutral	1,23	neutral	-2,32	low_impact	1,14	neutral	0,96	neutral	0,94	deleterious	0,34	6,1	0,28	0,45	neutral	0,41	neutral	0,19	neutral	0,3	neutral	0,36	3	neutral	0,36	deleterious	0,82	neutral	-6	neutral	0,14	medium_impact	1,95	medium_impact	0,35	medium_impact	-0,19	0,29	0,8	9,22	8,54	N	0,32	N	0,13	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5191	5191	C	A	MI.14276	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	722	241	T	K	aCa/aAa	0,36	0	0	benign	0,12	neutral	0,3	neutral	4,63	neutral	-0,92	deleterious	-3,67	neutral_impact	0,8	neutral	0,86	neutral	0,37	deleterious	2,72	20,9	0,13	0,4	disease	0,82	disease	0,6	disease	0,69	disease	0,73	5	neutral	0,66	deleterious	0,59	neutral	-6	neutral	0,38	medium_impact	-0,01	medium_impact	0	medium_impact	-0,47	0,34	0,8	9,22	8,54	N	0,29	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5191	5191	C	T	MI.14277	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	722	241	T	M	aCa/aTa	0,36	0	0	benign	0,01	neutral	0,32	neutral	4,62	neutral	-0,7	neutral	-2,45	low_impact	1,36	neutral	0,96	neutral	0,73	deleterious	0,76	9,21	0,11	0,4	disease	0,5	neutral	0,35	neutral	0,3	neutral	0,25	5	neutral	0,67	deleterious	0,66	neutral	-6	neutral	0,15	medium_impact	1,03	medium_impact	0,03	medium_impact	0	0,51	0,8	9,22	8,54	N	0,38	N	0,13	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5193	5193	C	T	MI.14278	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	724	242	P	S	Ccc/Tcc	-6,12	0	0	probably_damaging	0,95	neutral	0,62	neutral	4,7	neutral	2,32	neutral	0,4	neutral_impact	-2,01	neutral	0,78	neutral	0,98	neutral	1,79	14,95	0,23	0,45	neutral	0,38	neutral	0,08	neutral	0,16	neutral	0,26	5	neutral	0,94	neutral	0,34	neutral	-2	deleterious	0,62	low_impact	-1,97	medium_impact	0,33	low_impact	-2,84	0,08	0,8	9,8	8,71	N	0,4	N	0,21	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5193	5193	C	G	MI.14279	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	724	242	P	A	Ccc/Gcc	-6,12	0	0	possibly_damaging	0,78	neutral	0,75	neutral	4,75	neutral	2,96	neutral	0,11	neutral_impact	-2,02	neutral	0,83	neutral	0,93	neutral	-0,54	0,17	0,18	0,45	neutral	0,48	neutral	0,03	neutral	0,18	neutral	0,2	6	neutral	0,74	deleterious	0,49	neutral	-3	deleterious	0,6	low_impact	-1,3	medium_impact	0,47	low_impact	-2,85	0,73	0,85	9,8	8,71	N	0,42	N	0,21	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9197	9197	A	T	MI.1428	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	671	224	D	V	gAc/gTc	6,14	1	0	possibly_damaging	0,67	deleterious	0	neutral	4,21	deleterious	-5,38	deleterious	-5,7	medium_impact	2,88	neutral	0,82	neutral	0,48	deleterious	3,88	23,5	0,27	0,65	NA	NA	neutral	0,35	disease	0,56	neutral	0,36	3	deleterious	1	neutral	0,17	deleterious	4	deleterious	0,54	low_impact	-1,05	low_impact	-1,4	medium_impact	1,37	0,3	0,9	NA	NA	P	0,56	P	0,97	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5193	5193	C	A	MI.14280	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	724	242	P	T	Ccc/Acc	-6,12	0	0	probably_damaging	0,93	neutral	0,57	neutral	4,8	neutral	3,56	neutral	0,81	neutral_impact	-2	neutral	0,85	neutral	0,99	neutral	1,05	10,95	0,18	0,45	neutral	0,36	neutral	0,05	neutral	0,17	neutral	0,23	5	neutral	0,92	neutral	0,32	neutral	-2	deleterious	0,61	low_impact	-1,83	medium_impact	0,28	low_impact	-2,83	0,63	0,8	9,8	8,71	N	0,41	N	0,18	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5194	5194	C	G	MI.14281	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	725	242	P	R	cCc/cGc	-3,11	0	0	probably_damaging	0,96	neutral	0,45	neutral	4,65	neutral	0,59	neutral	-1,59	neutral_impact	0	neutral	0,89	neutral	0,4	deleterious	3,48	23,1	0,1	0,4	disease	0,67	neutral	0,35	disease	0,59	disease	0,64	3	neutral	0,96	neutral	0,25	neutral	-2	deleterious	0,7	low_impact	-2,06	medium_impact	0,16	low_impact	-1,14	0,43	0,8	9,8	8,71	N	0,36	N	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5194	5194	C	A	MI.14282	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	725	242	P	H	cCc/cAc	-3,11	0	0	probably_damaging	0,98	neutral	0,52	neutral	4,64	neutral	0,05	neutral	-2	neutral_impact	0	neutral	0,87	neutral	0,43	deleterious	4,11	23,7	0,11	0,4	disease	0,74	neutral	0,22	disease	0,53	disease	0,52	0	deleterious	0,98	neutral	0,27	neutral	-2	deleterious	0,68	low_impact	-2,34	medium_impact	0,23	low_impact	-1,14	0,39	0,8	9,8	8,71	N	0,31	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5194	5194	C	T	MI.14283	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	725	242	P	L	cCc/cTc	-3,11	0	0	benign	0,15	neutral	1	neutral	5,01	neutral	4,79	neutral	-0,73	neutral_impact	-1,84	neutral	0,95	neutral	0,89	deleterious	0,74	9,07	0,12	0,4	disease	0,78	neutral	0,21	neutral	0,29	disease	0,52	0	neutral	0,15	deleterious	0,93	neutral	-6	neutral	0,29	medium_impact	-0,11	high_impact	1,87	low_impact	-2,69	0,76	0,85	9,8	8,71	N	0,3	N	0,63	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5196	5196	T	A	MI.14284	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	727	243	L	M	Tta/Ata	-10,05	0	0	benign	0,24	neutral	0,38	neutral	4,43	neutral	-2,72	neutral	-0,14	low_impact	0,88	neutral	0,88	neutral	0,91	neutral	1,72	14,54	0,27	0,45	disease	0,72	neutral	0,04	neutral	0,16	neutral	0,4	2	neutral	0,54	deleterious	0,57	neutral	-6	neutral	0,36	medium_impact	-0,34	medium_impact	0,09	medium_impact	-0,4	0,51	0,8	4,32	7,96	N	0,54	P	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5196	5196	T	G	MI.14285	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	727	243	L	V	Tta/Gta	-10,05	0	0	benign	0,1	neutral	0,48	neutral	4,53	neutral	-1,03	neutral	-1,25	low_impact	1,46	neutral	0,91	neutral	0,48	deleterious	2,4	18,85	0,25	0,45	disease	0,56	neutral	0,18	neutral	0,25	neutral	0,38	2	neutral	0,45	deleterious	0,69	neutral	-6	neutral	0,24	medium_impact	0,08	medium_impact	0,19	medium_impact	0,09	0,59	0,8	4,32	7,96	N	0,38	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5197	5197	T	G	MI.14286	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	728	243	L	W	tTa/tGa	-2,65	0	0	probably_damaging	0,98	neutral	0,18	neutral	4,42	deleterious	-5,94	deleterious	-3,73	medium_impact	2,48	neutral	0,92	damaging	0,16	deleterious	3,8	23,4	0,05	0,35	disease	0,96	disease	0,51	neutral	0,49	disease	0,75	5	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,78	low_impact	-2,34	medium_impact	-0,16	medium_impact	0,94	0,22	0,8	4,32	7,96	N	0,45	N	0,83	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5197	5197	T	C	MI.14287	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	728	243	L	S	tTa/tCa	-2,65	0	0	possibly_damaging	0,78	neutral	0,54	neutral	4,51	neutral	-2,91	neutral	-2,47	neutral_impact	0,67	neutral	0,85	neutral	0,82	deleterious	2,63	20,4	0,05	0,35	disease	0,83	neutral	0,29	neutral	0,33	disease	0,6	2	neutral	0,75	neutral	0,38	neutral	-3	deleterious	0,67	low_impact	-1,3	medium_impact	0,25	medium_impact	-0,58	0,2	0,8	4,32	7,96	N	0,28	N	0,74	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5198	5198	A	T	MI.14288	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	729	243	L	F	ttA/ttT	-0,11	0	0,01	probably_damaging	0,92	neutral	0,85	neutral	4,41	neutral	-2,37	neutral	-2,27	low_impact	1,32	neutral	0,91	neutral	0,67	deleterious	2,57	19,94	0,18	0,45	disease	0,76	neutral	0,28	neutral	0,29	disease	0,58	2	neutral	0,91	neutral	0,47	neutral	-2	deleterious	0,69	low_impact	-1,77	medium_impact	0,63	medium_impact	-0,03	0,61	0,8	4,32	7,96	N	0,31	N	0,43	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5198	5198	A	C	MI.14289	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	729	243	L	F	ttA/ttC	-0,11	0	0,01	probably_damaging	0,92	neutral	0,85	neutral	4,41	neutral	-2,37	neutral	-2,27	low_impact	1,32	neutral	0,91	neutral	0,67	deleterious	2,43	19,02	0,18	0,45	disease	0,76	neutral	0,28	neutral	0,29	disease	0,58	2	neutral	0,91	neutral	0,47	neutral	-2	deleterious	0,69	low_impact	-1,77	medium_impact	0,63	medium_impact	-0,03	0,61	0,8	4,32	7,96	N	0,28	N	0,43	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9198	9198	C	A	MI.1429	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	672	224	D	E	gaC/gaA	7,07	1	0	benign	0,01	neutral	1	neutral	4,45	neutral	-1,79	neutral	-0,99	neutral_impact	-1,33	neutral	0,87	neutral	0,7	neutral	-0,21	1,05	0,58	0,7	NA	NA	neutral	0,03	neutral	0,23	neutral	0,19	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,14	high_impact	1,98	low_impact	-2,24	0,55	0,9	NA	NA	N	0,49	N	0,85	polymorphism	0,8	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5199	5199	A	T	MI.14290	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	730	244	I	F	Att/Ttt	-12,13	0	0	possibly_damaging	0,48	neutral	0,55	neutral	4,69	neutral	0,33	neutral	-2,39	low_impact	0,94	neutral	0,91	neutral	0,76	deleterious	3,73	23,3	0,14	0,4	disease	0,81	neutral	0,4	neutral	0,29	disease	0,64	3	neutral	0,45	deleterious	0,54	neutral	-3	deleterious	0,57	medium_impact	-0,77	medium_impact	0,26	medium_impact	-0,35	0,52	0,8	2,88	7,94	N	0,29	N	0,54	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5199	5199	A	G	MI.14291	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	730	244	I	V	Att/Gtt	-12,13	0	0	benign	0,01	neutral	0,4	neutral	4,57	neutral	-0,76	neutral	-0,44	low_impact	1,36	neutral	0,96	neutral	0,9	neutral	1,76	14,72	0,33	0,5	neutral	0,42	neutral	0,12	neutral	0,24	neutral	0,31	4	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	0,11	medium_impact	0	0,4	0,8	2,88	7,94	N	0,49	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5199	5199	A	C	MI.14292	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	730	244	I	L	Att/Ctt	-12,13	0	0	benign	0,06	neutral	1	neutral	4,92	neutral	1,43	neutral	-0,52	neutral_impact	0,32	neutral	0,87	neutral	0,94	deleterious	2,35	18,51	0,22	0,45	disease	0,57	neutral	0,11	neutral	0,19	neutral	0,36	3	neutral	0,06	deleterious	0,97	neutral	-6	neutral	0,17	medium_impact	0,3	high_impact	1,87	medium_impact	-0,88	0,52	0,8	2,88	7,94	N	0,42	N	0,64	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5200	5200	T	G	MI.14293	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	731	244	I	S	aTt/aGt	-0,57	0	0	benign	0,28	neutral	0,41	neutral	4,49	neutral	-2,54	deleterious	-3,38	low_impact	0,96	neutral	0,84	neutral	0,96	deleterious	3,32	22,9	0,05	0,35	disease	0,54	neutral	0,45	neutral	0,31	neutral	0,44	1	neutral	0,5	deleterious	0,57	neutral	-6	deleterious	0,44	medium_impact	-0,42	medium_impact	0,12	medium_impact	-0,34	0,3	0,8	2,88	7,94	N	0,35	N	0,79	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5200	5200	T	C	MI.14294	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	731	244	I	T	aTt/aCt	-0,57	0	0	benign	0,02	neutral	0,41	neutral	4,52	neutral	-1,57	neutral	-2,24	neutral_impact	0,78	neutral	0,96	neutral	0,98	deleterious	1,83	15,15	0,09	0,35	disease	0,58	neutral	0,14	neutral	0,22	neutral	0,32	4	neutral	0,57	deleterious	0,7	neutral	-6	neutral	0,16	medium_impact	0,75	medium_impact	0,12	medium_impact	-0,49	0,31	0,8	2,88	7,94	N	0,43	N	0,62	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5200	5200	T	A	MI.14295	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	731	244	I	N	aTt/aAt	-0,57	0	0	possibly_damaging	0,48	neutral	0,2	neutral	4,47	deleterious	-3,78	deleterious	-4,35	medium_impact	2,62	neutral	0,88	neutral	0,44	deleterious	4,58	24,4	0,11	0,4	disease	0,64	disease	0,59	disease	0,55	disease	0,65	3	neutral	0,78	neutral	0,36	NA	0	deleterious	0,66	medium_impact	-0,77	medium_impact	-0,13	medium_impact	1,06	0,38	0,8	2,88	7,94	N	0,43	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5201	5201	T	A	MI.14296	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	732	244	I	M	atT/atA	0,59	0	0,01	benign	0,04	neutral	0,27	neutral	4,58	neutral	-0,68	neutral	-0,63	low_impact	0,83	neutral	0,96	neutral	0,94	deleterious	2,2	17,54	0,23	0,45	disease	0,68	neutral	0,12	neutral	0,14	neutral	0,39	2	neutral	0,71	deleterious	0,62	neutral	-6	neutral	0,18	medium_impact	0,47	medium_impact	-0,03	medium_impact	-0,45	0,51	0,8	2,88	7,94	N	0,51	P	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5201	5201	T	G	MI.14297	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	732	244	I	M	atT/atG	0,59	0	0,01	benign	0,04	neutral	0,27	neutral	4,58	neutral	-0,68	neutral	-0,63	low_impact	0,83	neutral	0,96	neutral	0,94	deleterious	1,93	15,77	0,23	0,45	disease	0,68	neutral	0,12	neutral	0,14	neutral	0,39	2	neutral	0,71	deleterious	0,62	neutral	-6	neutral	0,18	medium_impact	0,47	medium_impact	-0,03	medium_impact	-0,45	0,51	0,8	2,88	7,94	N	0,51	P	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5202	5202	C	T	MI.14298	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	733	245	P	S	Cca/Tca	-8,43	0	0	benign	0,01	neutral	0,48	neutral	4,74	neutral	2,94	neutral	0,6	neutral_impact	0,26	neutral	0,96	neutral	0,93	deleterious	0,82	9,58	0,17	0,45	neutral	0,47	neutral	0,11	neutral	0,19	neutral	0,33	3	neutral	0,5	deleterious	0,74	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,19	medium_impact	-0,93	0,14	0,8	3,17	8,68	N	0,5	N	0,2	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5202	5202	C	G	MI.14299	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	733	245	P	A	Cca/Gca	-8,43	0	0	benign	0	neutral	0,33	neutral	4,74	neutral	2,88	neutral	1,02	neutral_impact	0,37	neutral	0,97	neutral	0,96	deleterious	0,33	6	0,17	0,45	disease	0,51	neutral	0,06	neutral	0,22	neutral	0,24	5	neutral	0,67	deleterious	0,67	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,04	medium_impact	-0,83	0,55	0,8	3,17	8,68	N	0,49	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8594	8594	T	G	MI.143	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	68	23	I	S	aTc/aGc	2,67	0,98	0	possibly_damaging	0,68	neutral	0,56	neutral	4,29	neutral	-1,62	neutral	-2,33	neutral_impact	-0,8	neutral	0,79	neutral	0,66	deleterious	2,5	19,47	0,33	0,65	disease	0,56	neutral	0,32	neutral	0,33	disease	0,61	2	neutral	0,64	neutral	0,44	neutral	-3	deleterious	0,49	low_impact	-1,07	medium_impact	0,35	low_impact	-1,78	0,58	0,9	19,03	10,37	N	0,36	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9198	9198	C	G	MI.1430	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	672	224	D	E	gaC/gaG	7,07	1	0	benign	0,01	neutral	1	neutral	4,45	neutral	-1,79	neutral	-0,99	neutral_impact	-1,33	neutral	0,87	neutral	0,7	neutral	-0,53	0,18	0,58	0,7	NA	NA	neutral	0,03	neutral	0,23	neutral	0,19	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,14	high_impact	1,98	low_impact	-2,24	0,55	0,9	NA	NA	N	0,49	N	0,85	polymorphism	0,8	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5202	5202	C	A	MI.14300	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	733	245	P	T	Cca/Aca	-8,43	0	0	benign	0,01	neutral	0,25	neutral	4,73	neutral	2,71	neutral	1,43	neutral_impact	0,2	neutral	0,9	neutral	0,95	neutral	0,98	10,57	0,16	0,45	disease	0,53	neutral	0,06	neutral	0,18	neutral	0,29	4	neutral	0,74	deleterious	0,62	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	-0,06	medium_impact	-0,98	0,56	0,8	3,17	8,68	P	0,57	P	0,32	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5203	5203	C	T	MI.14301	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	734	245	P	L	cCa/cTa	-4,5	0	0	benign	0,01	neutral	1	neutral	4,91	neutral	4,27	neutral	4,13	neutral_impact	-1,24	neutral	0,92	neutral	0,98	neutral	1,36	12,58	0,12	0,4	disease	0,6	neutral	0,11	neutral	0,19	neutral	0,34	3	neutral	0,01	deleterious	1	neutral	-6	neutral	0,13	medium_impact	1,03	high_impact	1,87	low_impact	-2,19	0,66	0,8	3,17	8,68	N	0,3	N	0,19	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5203	5203	C	G	MI.14302	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	734	245	P	R	cCa/cGa	-4,5	0	0	possibly_damaging	0,46	neutral	0,17	neutral	4,65	neutral	0,61	neutral	0,13	medium_impact	2,06	neutral	0,9	neutral	0,41	deleterious	3,48	23,1	0,1	0,4	disease	0,74	neutral	0,33	disease	0,64	disease	0,66	3	neutral	0,81	neutral	0,36	NA	0	deleterious	0,54	medium_impact	-0,73	medium_impact	-0,17	medium_impact	0,59	0,4	0,8	3,17	8,68	N	0,51	P	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5203	5203	C	A	MI.14303	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	734	245	P	Q	cCa/cAa	-4,5	0	0	possibly_damaging	0,46	neutral	0,17	neutral	4,65	neutral	0,45	neutral	0,4	medium_impact	2,06	neutral	0,89	neutral	0,5	deleterious	3,95	23,6	0,12	0,4	disease	0,76	neutral	0,17	disease	0,52	neutral	0,47	1	neutral	0,81	neutral	0,36	NA	0	deleterious	0,59	medium_impact	-0,73	medium_impact	-0,17	medium_impact	0,59	0,39	0,8	3,17	8,68	N	0,52	P	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5205	5205	T	A	MI.14304	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	736	246	S	T	Tcc/Acc	-1,26	0	0	benign	0,25	neutral	0,51	neutral	4,66	neutral	0,36	neutral	1,02	neutral_impact	-0,24	neutral	0,92	neutral	0,98	deleterious	2,02	16,32	0,26	0,45	disease	0,74	neutral	0,07	neutral	0,14	neutral	0,44	1	neutral	0,39	deleterious	0,63	neutral	-6	neutral	0,39	medium_impact	-0,36	medium_impact	0,22	low_impact	-1,35	0,54	0,8	0,86	7,55	N	0,46	N	0,15	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5205	5205	T	G	MI.14305	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	736	246	S	A	Tcc/Gcc	-1,26	0	0	benign	0,01	neutral	0,69	neutral	4,65	neutral	0,08	neutral	0,41	neutral_impact	-0,19	neutral	0,96	neutral	0,96	deleterious	2,51	19,55	0,24	0,45	neutral	0,4	neutral	0,12	neutral	0,18	neutral	0,32	4	neutral	0,29	deleterious	0,84	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,4	low_impact	-1,3	0,43	0,8	0,86	7,55	N	0,38	N	0,14	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5205	5205	T	C	MI.14306	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	736	246	S	P	Tcc/Ccc	-1,26	0	0	benign	0,02	neutral	0,37	neutral	4,59	neutral	-2,2	neutral	-1,22	low_impact	1,47	neutral	0,95	neutral	0,62	deleterious	4,03	23,7	0,06	0,35	disease	0,9	disease	0,64	disease	0,56	disease	0,71	4	neutral	0,62	deleterious	0,68	neutral	-6	neutral	0,29	medium_impact	0,75	medium_impact	0,08	medium_impact	0,09	0,38	0,8	0,86	7,55	N	0,3	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5206	5206	C	T	MI.14307	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	737	246	S	F	tCc/tTc	-3,58	0	0	benign	0,02	neutral	0,37	neutral	4,69	neutral	0,82	neutral	-0,04	neutral_impact	-0,34	neutral	0,95	neutral	0,84	deleterious	3,17	22,7	0,09	0,35	neutral	0,46	neutral	0,36	neutral	0,37	neutral	0,46	1	neutral	0,62	deleterious	0,68	neutral	-6	neutral	0,14	medium_impact	0,75	medium_impact	0,08	low_impact	-1,43	0,16	0,8	0,86	7,55	N	0,36	N	0,47	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5206	5206	C	A	MI.14308	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	737	246	S	Y	tCc/tAc	-3,58	0	0	benign	0,4	neutral	0,26	neutral	4,61	neutral	-1,16	neutral	-0,55	low_impact	0,92	neutral	0,9	neutral	0,62	deleterious	4,22	23,9	0,07	0,35	disease	0,55	neutral	0,34	neutral	0,48	disease	0,59	2	neutral	0,7	neutral	0,43	neutral	-6	deleterious	0,45	medium_impact	-0,64	medium_impact	-0,04	medium_impact	-0,37	0,31	0,8	0,86	7,55	N	0,46	N	0,5	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5206	5206	C	G	MI.14309	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	737	246	S	C	tCc/tGc	-3,58	0	0	possibly_damaging	0,89	neutral	0,09	neutral	4,62	neutral	-0,74	neutral	-0,27	neutral_impact	0,57	neutral	0,81	neutral	0,48	deleterious	3,62	23,2	0,07	0,35	disease	0,85	neutral	0,37	neutral	0,42	disease	0,66	3	neutral	0,97	neutral	0,1	neutral	-3	deleterious	0,69	low_impact	-1,63	medium_impact	-0,35	medium_impact	-0,67	0,25	0,8	0,86	7,55	N	0,4	N	0,47	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9199	9199	A	T	MI.1431	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	673	225	N	Y	Aac/Tac	-1,03	0,02	0	probably_damaging	0,99	neutral	0,16	neutral	4,52	neutral	-2,9	deleterious	-6,88	high_impact	3,57	damaging	0,55	neutral	0,36	deleterious	3,78	23,4	0,46	0,65	NA	NA	neutral	0,49	disease	0,63	disease	0,53	1	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,75	low_impact	-2,65	medium_impact	-0,12	medium_impact	1,96	0,56	0,9	NA	NA	N	0,36	N	1	disease_causing	0,98	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5208	5208	A	G	MI.14310	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	739	247	T	A	Acc/Gcc	-13,06	0	0	benign	0,01	neutral	0,56	neutral	4,67	neutral	0,34	neutral	-1,64	low_impact	1,48	neutral	0,91	neutral	0,67	neutral	0,95	10,37	0,23	0,45	NA	NA	neutral	0,2	neutral	0,5	neutral	0,2	6	neutral	0,42	deleterious	0,78	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	0,27	medium_impact	0,1	0,39	0,8	5,48	7,87	N	0,34	N	0,36	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5208	5208	A	C	MI.14311	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	739	247	T	P	Acc/Ccc	-13,06	0	0	possibly_damaging	0,57	neutral	0,26	neutral	4,52	neutral	-2,56	deleterious	-3,14	medium_impact	2,87	neutral	0,76	neutral	0,31	deleterious	3,65	23,2	0,06	0,35	NA	NA	disease	0,62	disease	0,72	disease	0,67	3	neutral	0,74	neutral	0,35	NA	0	deleterious	0,67	medium_impact	-0,91	medium_impact	-0,04	medium_impact	1,27	0,45	0,8	5,48	7,87	N	0,31	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5208	5208	A	T	MI.14312	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	739	247	T	S	Acc/Tcc	-13,06	0	0	benign	0,2	neutral	0,56	neutral	4,6	neutral	-1,28	neutral	-1,75	low_impact	1,05	neutral	0,89	neutral	0,94	neutral	0,98	10,52	0,38	0,5	NA	NA	neutral	0,23	neutral	0,39	neutral	0,17	7	neutral	0,33	deleterious	0,68	neutral	-6	neutral	0,34	medium_impact	-0,25	medium_impact	0,27	medium_impact	-0,26	0,65	0,8	5,48	7,87	N	0,36	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5209	5209	C	A	MI.14313	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	740	247	T	N	aCc/aAc	-0,57	0	0	possibly_damaging	0,65	neutral	0,33	neutral	4,55	deleterious	-3,48	deleterious	-2,87	low_impact	0,98	neutral	0,91	neutral	0,59	deleterious	3,39	23	0,25	0,45	NA	NA	neutral	0,45	disease	0,62	neutral	0,42	2	neutral	0,72	neutral	0,34	neutral	-3	deleterious	0,64	low_impact	-1,04	medium_impact	0,04	medium_impact	-0,32	0,64	0,8	5,48	7,87	N	0,39	N	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5209	5209	C	T	MI.14314	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	740	247	T	I	aCc/aTc	-0,57	0	0	benign	0,01	neutral	0,53	neutral	4,65	neutral	-1,16	neutral	-0,26	low_impact	0,81	neutral	0,93	neutral	0,94	deleterious	0,25	5,17	0,12	0,4	NA	NA	neutral	0,21	neutral	0,37	neutral	0,19	6	neutral	0,45	deleterious	0,76	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	0,24	medium_impact	-0,46	0,68	0,85	5,48	7,87	N	0,33	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5209	5209	C	G	MI.14315	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	740	247	T	S	aCc/aGc	-0,57	0	0	benign	0,2	neutral	0,56	neutral	4,6	neutral	-1,28	neutral	-1,75	low_impact	1,05	neutral	0,89	neutral	0,94	deleterious	0,69	8,78	0,38	0,5	NA	NA	neutral	0,23	neutral	0,39	neutral	0,17	7	neutral	0,33	deleterious	0,68	neutral	-6	neutral	0,34	medium_impact	-0,25	medium_impact	0,27	medium_impact	-0,26	0,65	0,8	5,48	7,87	N	0,36	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5211	5211	C	T	MI.14316	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	742	248	L	F	Ctc/Ttc	-8,66	0	0	probably_damaging	0,95	neutral	0,39	neutral	4,46	neutral	-1,71	deleterious	-3,22	low_impact	1,57	neutral	0,91	neutral	0,76	deleterious	4,01	23,6	0,29	0,45	disease	0,68	neutral	0,33	disease	0,58	disease	0,59	2	neutral	0,95	neutral	0,22	neutral	-2	deleterious	0,7	low_impact	-1,97	medium_impact	0,1	medium_impact	0,18	0,63	0,8	NA	NA	N	0,41	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5211	5211	C	G	MI.14317	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	742	248	L	V	Ctc/Gtc	-8,66	0	0	possibly_damaging	0,67	neutral	0,3	neutral	4,56	neutral	-1,79	neutral	-2,25	medium_impact	2,87	neutral	0,93	neutral	0,54	deleterious	3,52	23,1	0,37	0,5	disease	0,67	neutral	0,29	disease	0,58	disease	0,55	1	neutral	0,75	neutral	0,32	NA	0	deleterious	0,64	low_impact	-1,08	medium_impact	0	medium_impact	1,27	0,54	0,8	NA	NA	N	0,44	N	0,61	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5211	5211	C	A	MI.14318	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	742	248	L	I	Ctc/Atc	-8,66	0	0	possibly_damaging	0,77	neutral	0,31	neutral	4,6	neutral	-1,75	neutral	-1,59	low_impact	1,93	neutral	0,94	neutral	0,71	deleterious	4,14	23,8	0,39	0,5	disease	0,55	neutral	0,27	disease	0,56	disease	0,53	1	neutral	0,81	neutral	0,27	neutral	-3	deleterious	0,64	low_impact	-1,28	medium_impact	0,02	medium_impact	0,48	0,61	0,8	NA	NA	N	0,46	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5212	5212	T	C	MI.14319	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	743	248	L	P	cTc/cCc	0,13	0,01	0	probably_damaging	0,98	neutral	0,16	neutral	4,41	deleterious	-5,26	deleterious	-5,79	high_impact	3,76	neutral	0,83	neutral	0,35	deleterious	3,99	23,6	0,02	0,35	neutral	0,45	disease	0,6	disease	0,77	disease	0,68	4	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,73	low_impact	-2,34	medium_impact	-0,19	high_impact	2,02	0,4	0,8	NA	NA	N	0,43	N	0,9	polymorphism	1	0,29	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	9199	9199	A	C	MI.1432	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	673	225	N	H	Aac/Cac	-1,03	0,02	0	probably_damaging	0,99	neutral	0,36	neutral	4,56	neutral	-2,41	deleterious	-4,3	low_impact	1,64	damaging	0,55	neutral	0,34	deleterious	3,22	22,7	0,61	0,7	NA	NA	neutral	0,35	disease	0,62	neutral	0,36	3	deleterious	0,99	neutral	0,19	neutral	-2	deleterious	0,74	low_impact	-2,65	medium_impact	0,15	medium_impact	0,31	0,54	0,9	NA	NA	N	0,33	N	0,98	disease_causing	0,93	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5212	5212	T	A	MI.14320	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	743	248	L	H	cTc/cAc	0,13	0,01	0	probably_damaging	0,99	neutral	0,22	neutral	4,41	deleterious	-5,21	deleterious	-5,79	high_impact	3,76	neutral	0,86	neutral	0,4	deleterious	4,2	23,9	0,04	0,35	disease	0,92	disease	0,59	disease	0,73	disease	0,73	5	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,77	low_impact	-2,62	medium_impact	-0,1	high_impact	2,02	0,29	0,8	NA	NA	N	0,4	N	0,91	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5212	5212	T	G	MI.14321	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	743	248	L	R	cTc/cGc	0,13	0,01	0	probably_damaging	0,97	neutral	0,18	neutral	4,42	deleterious	-4,69	deleterious	-4,83	high_impact	3,76	neutral	0,84	neutral	0,39	deleterious	4,28	24	0,02	0,35	disease	0,88	disease	0,66	disease	0,76	disease	0,67	3	deleterious	0,98	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-2,18	medium_impact	-0,16	high_impact	2,02	0,28	0,8	NA	NA	N	0,45	N	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5214	5214	C	T	MI.14322	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	745	249	L	F	Ctc/Ttc	-13,06	0	0	possibly_damaging	0,88	neutral	0,74	neutral	4,3	neutral	-1,52	deleterious	-3,21	medium_impact	2,42	neutral	0,84	neutral	0,45	deleterious	4,07	23,7	0,12	0,4	disease	0,81	neutral	0,32	disease	0,51	disease	0,6	2	neutral	0,86	neutral	0,43	NA	0	deleterious	0,72	low_impact	-1,59	medium_impact	0,46	medium_impact	0,89	0,48	0,8	NA	NA	N	0,25	N	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5214	5214	C	G	MI.14323	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	745	249	L	V	Ctc/Gtc	-13,06	0	0	possibly_damaging	0,54	neutral	0,52	neutral	4,23	neutral	-2,86	neutral	-2,23	medium_impact	2,77	neutral	0,87	neutral	0,52	deleterious	3,52	23,1	0,16	0,45	disease	0,68	neutral	0,28	disease	0,68	disease	0,57	1	neutral	0,52	deleterious	0,49	NA	0	deleterious	0,61	medium_impact	-0,86	medium_impact	0,23	medium_impact	1,19	0,55	0,8	NA	NA	N	0,26	N	0,6	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5214	5214	C	A	MI.14324	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	745	249	L	I	Ctc/Atc	-13,06	0	0	possibly_damaging	0,66	neutral	0,36	neutral	4,21	neutral	-2,68	neutral	-1,61	medium_impact	2,38	neutral	0,88	neutral	0,62	deleterious	4,2	23,9	0,19	0,45	disease	0,62	neutral	0,24	disease	0,6	disease	0,53	1	neutral	0,7	neutral	0,35	NA	0	deleterious	0,61	low_impact	-1,06	medium_impact	0,07	medium_impact	0,86	0,61	0,8	NA	NA	N	0,37	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5215	5215	T	C	MI.14325	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	746	249	L	P	cTc/cCc	-2,19	0	0	probably_damaging	0,97	neutral	0,23	neutral	4,14	deleterious	-6,25	deleterious	-5,78	high_impact	3,92	neutral	0,74	neutral	0,3	deleterious	3,96	23,6	0,02	0,35	disease	0,96	disease	0,6	disease	0,78	disease	0,8	6	neutral	0,98	neutral	0,13	deleterious	2	deleterious	0,82	low_impact	-2,18	medium_impact	-0,08	high_impact	2,16	0,2	0,8	NA	NA	N	0,38	N	0,89	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5215	5215	T	G	MI.14326	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	746	249	L	R	cTc/cGc	-2,19	0	0	probably_damaging	0,93	neutral	0,33	neutral	4,15	deleterious	-5,69	deleterious	-4,82	high_impact	3,92	neutral	0,79	neutral	0,35	deleterious	4,28	24	0,02	0,35	disease	0,95	disease	0,66	disease	0,78	disease	0,8	6	neutral	0,94	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-1,83	medium_impact	0,04	high_impact	2,16	0,2	0,8	NA	NA	N	0,42	N	0,94	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5215	5215	T	A	MI.14327	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	746	249	L	H	cTc/cAc	-2,19	0	0	probably_damaging	0,98	neutral	0,48	neutral	4,14	deleterious	-6,22	deleterious	-5,78	high_impact	3,92	neutral	0,82	neutral	0,38	deleterious	4,2	23,9	0,03	0,35	disease	0,91	disease	0,59	disease	0,75	disease	0,69	4	neutral	0,98	neutral	0,25	deleterious	2	deleterious	0,79	low_impact	-2,34	medium_impact	0,19	high_impact	2,16	0,28	0,8	NA	NA	N	0,4	N	0,88	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5217	5217	T	A	MI.14328	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	748	250	S	T	Tcc/Acc	-3,11	0	0	probably_damaging	1	neutral	0,39	neutral	4,27	deleterious	-3,58	deleterious	-2,87	medium_impact	3,15	neutral	0,95	damaging	0,22	deleterious	3,84	23,4	0,13	0,4	disease	0,66	neutral	0,42	disease	0,7	disease	0,58	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0,1	medium_impact	1,51	0,65	0,8	NA	NA	N	0,42	N	0,71	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5217	5217	T	G	MI.14329	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	748	250	S	A	Tcc/Gcc	-3,11	0	0	probably_damaging	1	neutral	0,51	neutral	4,41	neutral	-0,94	deleterious	-2,86	medium_impact	3,07	neutral	0,87	damaging	0,21	deleterious	3,73	23,3	0,14	0,4	neutral	0,48	neutral	0,3	disease	0,6	neutral	0,43	1	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,71	low_impact	-3,54	medium_impact	0,22	medium_impact	1,44	0,35	0,8	NA	NA	N	0,31	N	0,49	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9199	9199	A	G	MI.1433	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	673	225	N	D	Aac/Gac	-1,03	0,02	0	probably_damaging	0,95	deleterious	0,04	neutral	4,57	neutral	-0,89	deleterious	-4,28	medium_impact	2,67	neutral	0,69	neutral	0,47	deleterious	3,94	23,5	0,73	0,8	NA	NA	neutral	0,34	disease	0,62	neutral	0,39	2	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,71	low_impact	-1,97	medium_impact	-0,49	medium_impact	1,19	0,61	0,9	NA	NA	N	0,39	N	0,96	disease_causing	0,86	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5217	5217	T	C	MI.14330	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	748	250	S	P	Tcc/Ccc	-3,11	0	0	probably_damaging	1	neutral	0,21	neutral	4,22	deleterious	-5,58	deleterious	-4,79	medium_impact	3,49	neutral	0,84	damaging	0,09	deleterious	4,02	23,6	0,04	0,35	disease	0,67	disease	0,65	disease	0,8	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,11	medium_impact	1,79	0,34	0,8	NA	NA	N	0,38	N	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5218	5218	C	A	MI.14331	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	749	250	S	Y	tCc/tAc	5,68	1	0	probably_damaging	1	neutral	1	neutral	4,22	deleterious	-5,25	deleterious	-5,74	high_impact	4,04	neutral	0,89	damaging	0,08	deleterious	4,16	23,8	0,04	0,35	disease	0,83	disease	0,64	disease	0,71	disease	0,67	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,77	low_impact	-3,54	high_impact	1,87	high_impact	2,26	0,19	0,8	NA	NA	P	0,56	P	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5218	5218	C	G	MI.14332	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	749	250	S	C	tCc/tGc	5,68	1	0	probably_damaging	1	neutral	0,18	neutral	4,24	deleterious	-5,45	deleterious	-4,79	high_impact	4,04	neutral	0,87	damaging	0,1	deleterious	3,69	23,3	0,04	0,35	disease	0,92	disease	0,57	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,76	low_impact	-3,54	medium_impact	-0,16	high_impact	2,26	0,24	0,8	NA	NA	P	0,67	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5218	5218	C	T	MI.14333	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	749	250	S	F	tCc/tTc	5,68	1	0	probably_damaging	1	neutral	0,7	neutral	4,28	deleterious	-4,77	deleterious	-5,74	high_impact	4,04	neutral	0,8	damaging	0,07	deleterious	4,35	24,1	0,03	0,35	neutral	0,39	disease	0,66	disease	0,71	disease	0,67	3	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,71	low_impact	-3,54	medium_impact	0,41	high_impact	2,26	0,09	0,8	NA	NA	N	0,5	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5220	5220	C	G	MI.14334	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	751	251	L	V	Cta/Gta	-10,75	0	0	possibly_damaging	0,79	neutral	0,52	neutral	4,32	deleterious	-3	neutral	-2,24	high_impact	3,56	neutral	0,89	neutral	0,55	deleterious	3,51	23,1	0,28	0,45	disease	0,81	neutral	0,4	disease	0,69	disease	0,65	3	neutral	0,77	neutral	0,37	deleterious	1	deleterious	0,68	low_impact	-1,32	medium_impact	0,23	medium_impact	1,85	0,5	0,8	0,86	7,54	N	0,38	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5220	5220	C	A	MI.14335	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	751	251	L	M	Cta/Ata	-10,75	0	0	possibly_damaging	0,46	neutral	0,26	neutral	4,29	neutral	-2,11	neutral	-0,47	low_impact	1,63	neutral	0,87	neutral	0,87	deleterious	2,55	19,81	0,35	0,5	disease	0,68	neutral	0,22	neutral	0,44	neutral	0,47	1	neutral	0,71	neutral	0,4	neutral	-3	deleterious	0,57	medium_impact	-0,73	medium_impact	-0,04	medium_impact	0,23	0,57	0,8	0,86	7,54	N	0,47	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5221	5221	T	G	MI.14336	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	752	251	L	R	cTa/cGa	-0,57	0	0	probably_damaging	0,98	neutral	0,36	neutral	4,24	deleterious	-5,58	deleterious	-4,8	high_impact	3,91	neutral	0,86	neutral	0,38	deleterious	4,25	23,9	0,02	0,35	disease	0,75	disease	0,75	disease	0,78	disease	0,69	4	neutral	0,98	neutral	0,19	deleterious	2	deleterious	0,8	low_impact	-2,34	medium_impact	0,07	high_impact	2,15	0,12	0,8	0,86	7,54	N	0,49	N	0,95	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5221	5221	T	A	MI.14337	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	752	251	L	Q	cTa/cAa	-0,57	0	0	probably_damaging	0,98	neutral	0,3	neutral	4,24	deleterious	-5,63	deleterious	-4,51	high_impact	3,91	neutral	0,86	neutral	0,47	deleterious	4,14	23,8	0,03	0,35	disease	0,68	disease	0,65	disease	0,68	disease	0,65	3	neutral	0,98	neutral	0,16	deleterious	2	deleterious	0,74	low_impact	-2,34	medium_impact	0	high_impact	2,15	0,26	0,8	0,86	7,54	N	0,43	N	0,95	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5221	5221	T	C	MI.14338	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	752	251	L	P	cTa/cCa	-0,57	0	0	probably_damaging	0,99	neutral	0,28	neutral	4,23	deleterious	-6,15	deleterious	-5,74	high_impact	3,91	neutral	0,83	neutral	0,36	deleterious	3,98	23,6	0,02	0,35	disease	0,52	disease	0,66	disease	0,78	disease	0,68	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,76	low_impact	-2,62	medium_impact	-0,02	high_impact	2,15	0,27	0,8	0,86	7,54	N	0,44	N	0,88	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5223	5223	G	T	MI.14339	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	754	252	G	W	Gga/Tga	-0,11	0,48	0	probably_damaging	1	neutral	0,19	neutral	4,53	deleterious	-4,15	deleterious	-7,66	high_impact	3,86	neutral	0,84	damaging	0,07	deleterious	4,47	24,2	0,08	0,35	disease	0,79	disease	0,84	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,14	high_impact	2,11	0,08	0,8	NA	NA	N	0,38	N	0,99	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9200	9200	A	C	MI.1434	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	674	225	N	T	aAc/aCc	6,84	1	0	probably_damaging	0,97	neutral	0,11	neutral	4,6	neutral	-0,45	deleterious	-5,1	medium_impact	2,21	damaging	0,59	neutral	0,48	deleterious	3,6	23,2	0,59	0,7	NA	NA	neutral	0,38	disease	0,58	neutral	0,38	2	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,72	low_impact	-2,19	medium_impact	-0,22	medium_impact	0,8	0,6	0,9	NA	NA	P	0,55	P	0,96	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5223	5223	G	C	MI.14340	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	754	252	G	R	Gga/Cga	-0,11	0,48	0	probably_damaging	1	neutral	0,35	neutral	4,55	neutral	-2,81	deleterious	-7,66	high_impact	3,51	neutral	0,81	damaging	0,06	deleterious	3,96	23,6	0,05	0,35	disease	0,71	disease	0,87	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	0,06	medium_impact	1,81	0,5	0,8	NA	NA	N	0,38	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5224	5224	G	T	MI.14341	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	755	252	G	V	gGa/gTa	7,07	1	0	probably_damaging	1	neutral	0,52	neutral	4,65	neutral	0,25	deleterious	-8,62	high_impact	3,86	neutral	0,85	damaging	0,08	deleterious	3,84	23,4	0,07	0,35	disease	0,7	disease	0,79	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0,23	high_impact	2,11	0,11	0,8	NA	NA	P	0,56	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5224	5224	G	C	MI.14342	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	755	252	G	A	gGa/gCa	7,07	1	0	probably_damaging	1	neutral	0,55	neutral	4,68	neutral	2,52	deleterious	-5,74	low_impact	1,47	neutral	0,87	damaging	0,23	deleterious	3,15	22,6	0,17	0,45	neutral	0,43	neutral	0,14	neutral	0,38	neutral	0,28	4	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	0,26	medium_impact	0,09	0,3	0,8	NA	NA	N	0,52	P	0,74	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5224	5224	G	A	MI.14343	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	755	252	G	E	gGa/gAa	7,07	1	0	probably_damaging	1	neutral	0,27	neutral	4,55	deleterious	-3	deleterious	-7,66	high_impact	3,86	neutral	0,84	damaging	0,06	deleterious	3,96	23,6	0,06	0,35	neutral	0,38	disease	0,83	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,76	low_impact	-3,54	medium_impact	-0,03	high_impact	2,11	0,2	0,8	NA	NA	P	0,62	P	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5226	5226	G	C	MI.14344	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	757	253	G	R	Ggc/Cgc	-0,34	0,39	0	probably_damaging	1	neutral	0,35	neutral	3,6	deleterious	-10,56	deleterious	-7,66	high_impact	4,06	neutral	0,81	damaging	0,1	deleterious	4,05	23,7	0,01	0,35	disease	0,7	disease	0,85	disease	0,83	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	0,06	high_impact	2,27	0,57	0,8	0,58	7,14	N	0,43	N	1	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5226	5226	G	A	MI.14345	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	757	253	G	S	Ggc/Agc	-0,34	0,39	0	probably_damaging	1	neutral	0,4	neutral	3,68	deleterious	-6,89	deleterious	-5,75	high_impact	3,51	neutral	0,86	damaging	0,14	deleterious	4,23	23,9	0,02	0,35	neutral	0,33	disease	0,75	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,74	low_impact	-3,54	medium_impact	0,11	medium_impact	1,81	0,61	0,8	0,58	7,14	N	0,36	N	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5226	5226	G	T	MI.14346	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	757	253	G	C	Ggc/Tgc	-0,34	0,39	0	probably_damaging	1	neutral	0,18	neutral	3,59	deleterious	-10,11	deleterious	-8,62	high_impact	4,06	neutral	0,78	damaging	0,09	deleterious	4,28	24	0,02	0,35	disease	0,94	disease	0,83	disease	0,75	disease	0,66	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,16	high_impact	2,27	0,22	0,8	0,58	7,14	N	0,39	N	0,96	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5227	5227	G	C	MI.14347	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	758	253	G	A	gGc/gCc	7,3	1	0	probably_damaging	1	neutral	0,51	neutral	3,82	deleterious	-6,34	deleterious	-5,75	high_impact	4,06	neutral	0,83	damaging	0,13	deleterious	3,17	22,7	0,03	0,35	neutral	0,39	disease	0,62	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,75	low_impact	-3,54	medium_impact	0,22	high_impact	2,27	0,4	0,8	0,58	7,14	P	0,56	P	0,74	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5227	5227	G	T	MI.14348	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	758	253	G	V	gGc/gTc	7,3	1	0	probably_damaging	1	neutral	0,5	neutral	3,61	deleterious	-9,34	deleterious	-8,62	high_impact	4,06	neutral	0,68	damaging	0,1	deleterious	3,84	23,4	0,02	0,35	disease	0,65	disease	0,82	disease	0,77	disease	0,7	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,21	high_impact	2,27	0,21	0,8	0,58	7,14	P	0,61	P	0,97	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5227	5227	G	A	MI.14349	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	758	253	G	D	gGc/gAc	7,3	1	0	probably_damaging	1	neutral	0,2	neutral	3,6	deleterious	-10,05	deleterious	-6,7	high_impact	4,06	neutral	0,81	damaging	0,1	deleterious	3,97	23,6	0,01	0,35	disease	0,61	disease	0,83	disease	0,83	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,13	high_impact	2,27	0,13	0,8	0,58	7,14	P	0,59	P	0,95	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9200	9200	A	G	MI.1435	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	674	225	N	S	aAc/aGc	6,84	1	0	probably_damaging	0,95	neutral	0,18	neutral	4,64	neutral	0,33	deleterious	-4,19	low_impact	0,94	neutral	0,75	neutral	0,59	deleterious	3,29	22,8	0,71	0,75	NA	NA	neutral	0,29	disease	0,53	neutral	0,34	3	neutral	0,97	neutral	0,12	neutral	-2	deleterious	0,73	low_impact	-1,97	medium_impact	-0,08	medium_impact	-0,29	0,43	0,9	NA	NA	P	0,56	P	0,82	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5229	5229	C	G	MI.14350	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	760	254	L	V	Ctg/Gtg	-6,12	0	0	probably_damaging	1	neutral	0,55	neutral	4,41	neutral	-1,21	deleterious	-2,87	medium_impact	3,06	neutral	0,91	damaging	0,14	deleterious	3,49	23,1	0,13	0,4	NA	NA	neutral	0,39	disease	0,68	neutral	0,41	2	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,26	medium_impact	1,43	0,65	0,8	NA	NA	N	0,28	N	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5229	5229	C	A	MI.14351	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	760	254	L	M	Ctg/Atg	-6,12	0	0	probably_damaging	1	neutral	0,24	neutral	4,35	neutral	-2,34	neutral	-1,92	medium_impact	2,08	neutral	0,85	damaging	0,11	deleterious	3,82	23,4	0,15	0,4	NA	NA	neutral	0,38	disease	0,55	neutral	0,36	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	-0,07	medium_impact	0,61	0,61	0,8	NA	NA	N	0,32	N	0,88	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5230	5230	T	A	MI.14352	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	761	254	L	Q	cTg/cAg	0,59	0,13	0	probably_damaging	1	neutral	0,33	neutral	4,3	deleterious	-5,26	deleterious	-5,75	high_impact	3,96	neutral	0,83	damaging	0,11	deleterious	4,25	23,9	0,02	0,35	NA	NA	disease	0,68	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,04	high_impact	2,19	0,37	0,8	NA	NA	N	0,36	N	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5230	5230	T	C	MI.14353	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	761	254	L	P	cTg/cCg	0,59	0,13	0	probably_damaging	1	neutral	0,36	neutral	4,3	deleterious	-5,64	deleterious	-6,7	high_impact	3,62	neutral	0,81	damaging	0,09	deleterious	3,97	23,6	0,02	0,35	NA	NA	disease	0,63	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0,07	medium_impact	1,9	0,17	0,8	NA	NA	N	0,32	N	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5230	5230	T	G	MI.14354	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	761	254	L	R	cTg/cGg	0,59	0,13	0	probably_damaging	1	neutral	0,38	neutral	4,3	deleterious	-5,09	deleterious	-5,75	high_impact	3,96	neutral	0,81	damaging	0,09	deleterious	4,27	23,9	0,01	0,35	NA	NA	disease	0,74	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,09	high_impact	2,19	0,19	0,8	NA	NA	N	0,39	N	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5232	5232	C	T	MI.14355	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	763	255	P	S	Ccc/Tcc	-16,07	0	0	probably_damaging	1	neutral	0,49	neutral	3,54	deleterious	-7,55	deleterious	-7,66	high_impact	4,04	neutral	0,84	damaging	0,16	deleterious	3,96	23,6	0,05	0,35	disease	0,56	disease	0,66	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,75	low_impact	-3,54	medium_impact	0,2	high_impact	2,26	0,18	0,8	NA	NA	N	0,33	N	0,72	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5232	5232	C	G	MI.14356	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	763	255	P	A	Ccc/Gcc	-16,07	0	0	probably_damaging	1	neutral	0,58	neutral	3,56	deleterious	-7,04	deleterious	-7,66	high_impact	3,69	neutral	0,85	damaging	0,17	deleterious	3,16	22,6	0,07	0,35	disease	0,62	disease	0,52	disease	0,76	disease	0,7	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,75	low_impact	-3,54	medium_impact	0,29	medium_impact	1,96	0,48	0,8	NA	NA	N	0,28	N	0,72	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5232	5232	C	A	MI.14357	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	763	255	P	T	Ccc/Acc	-16,07	0	0	probably_damaging	1	neutral	0,45	neutral	3,54	deleterious	-7,99	deleterious	-7,66	medium_impact	3,48	neutral	0,83	damaging	0,12	deleterious	3,76	23,3	0,05	0,35	disease	0,8	disease	0,63	disease	0,76	disease	0,67	3	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,16	medium_impact	1,79	0,43	0,8	NA	NA	N	0,29	N	0,88	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5233	5233	C	T	MI.14358	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	764	255	P	L	cCc/cTc	5,45	0,99	0	probably_damaging	1	neutral	0,75	neutral	3,62	deleterious	-8	deleterious	-9,58	high_impact	3,69	neutral	0,92	damaging	0,12	deleterious	4,5	24,3	0,05	0,35	disease	0,69	disease	0,76	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	0,47	medium_impact	1,96	0,56	0,8	NA	NA	N	0,54	P	0,97	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5233	5233	C	A	MI.14359	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	764	255	P	H	cCc/cAc	5,45	0,99	0	probably_damaging	1	neutral	0,55	neutral	3,52	deleterious	-10,38	deleterious	-8,62	high_impact	4,04	neutral	0,84	damaging	0,1	deleterious	4,05	23,7	0,05	0,35	disease	0,89	disease	0,76	disease	0,81	disease	0,67	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0,26	high_impact	2,26	0,32	0,8	NA	NA	P	0,61	P	0,71	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9200	9200	A	T	MI.1436	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	674	225	N	I	aAc/aTc	6,84	1	0	probably_damaging	0,99	neutral	0,1	neutral	4,54	neutral	-2,04	deleterious	-7,73	low_impact	1,54	neutral	0,62	neutral	0,53	deleterious	4,23	23,9	0,45	0,65	NA	NA	disease	0,52	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,75	low_impact	-2,65	medium_impact	-0,25	medium_impact	0,22	0,49	0,9	NA	NA	P	0,49	N	1	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5233	5233	C	G	MI.14360	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	764	255	P	R	cCc/cGc	5,45	0,99	0	probably_damaging	1	neutral	0,39	neutral	3,53	deleterious	-9,61	deleterious	-8,62	high_impact	4,04	neutral	0,85	damaging	0,12	deleterious	3,64	23,2	0,04	0,35	disease	0,69	disease	0,78	disease	0,83	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	0,1	high_impact	2,26	0,3	0,8	NA	NA	P	0,63	P	0,56	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5235	5235	C	G	MI.14361	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	766	256	P	A	Ccg/Gcg	-12,13	0	0	probably_damaging	1	neutral	0,5	neutral	4,36	deleterious	-3,7	deleterious	-7,66	high_impact	4,04	neutral	0,83	damaging	0,16	deleterious	3,16	22,6	0,08	0,35	disease	0,52	disease	0,55	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,74	low_impact	-3,54	medium_impact	0,21	high_impact	2,26	0,66	0,8	NA	NA	N	0,33	N	0,72	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5235	5235	C	A	MI.14362	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	766	256	P	T	Ccg/Acg	-12,13	0	0	probably_damaging	1	neutral	0,39	neutral	4,35	deleterious	-4,19	deleterious	-7,66	medium_impact	3,34	neutral	0,83	damaging	0,12	deleterious	3,76	23,4	0,06	0,35	neutral	0,35	disease	0,67	disease	0,74	disease	0,68	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	0,1	medium_impact	1,67	0,51	0,8	NA	NA	N	0,31	N	0,88	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5235	5235	C	T	MI.14363	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	766	256	P	S	Ccg/Tcg	-12,13	0	0	probably_damaging	1	neutral	0,4	neutral	4,34	deleterious	-4,33	deleterious	-7,66	high_impact	4,04	neutral	0,83	damaging	0,16	deleterious	3,98	23,6	0,07	0,35	disease	0,65	disease	0,69	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,76	low_impact	-3,54	medium_impact	0,11	high_impact	2,26	0,14	0,8	NA	NA	N	0,34	N	0,72	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5236	5236	C	G	MI.14364	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	767	256	P	R	cCg/cGg	5,45	1	0	probably_damaging	1	neutral	0,35	neutral	4,32	deleterious	-5,56	deleterious	-8,62	high_impact	4,04	neutral	0,85	damaging	0,12	deleterious	3,68	23,3	0,04	0,35	disease	0,75	disease	0,82	disease	0,82	disease	0,68	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0,06	high_impact	2,26	0,26	0,8	NA	NA	P	0,63	P	0,56	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5236	5236	C	T	MI.14365	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	767	256	P	L	cCg/cTg	5,45	1	0	probably_damaging	1	neutral	0,66	neutral	4,46	neutral	-2,02	deleterious	-9,57	medium_impact	3,48	neutral	0,76	damaging	0,11	deleterious	4,48	24,2	0,06	0,35	neutral	0,39	disease	0,79	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0,37	medium_impact	1,79	0,5	0,8	NA	NA	N	0,44	N	0,97	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5236	5236	C	A	MI.14366	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	767	256	P	Q	cCg/cAg	5,45	1	0	probably_damaging	1	neutral	0,29	neutral	4,31	deleterious	-5,69	deleterious	-7,66	high_impact	4,04	neutral	0,83	damaging	0,11	deleterious	4,16	23,8	0,06	0,35	disease	0,53	disease	0,79	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,75	low_impact	-3,54	medium_impact	-0,01	high_impact	2,26	0,32	0,8	NA	NA	P	0,58	P	0,83	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5238	5238	C	G	MI.14367	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	769	257	L	V	Cta/Gta	-4,73	0	0	probably_damaging	1	neutral	0,47	neutral	4,36	neutral	-2,62	deleterious	-2,87	high_impact	3,78	neutral	0,85	damaging	0,14	deleterious	3,5	23,1	0,21	0,45	NA	NA	neutral	0,5	disease	0,67	disease	0,61	2	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,76	low_impact	-3,54	medium_impact	0,18	high_impact	2,04	0,49	0,8	NA	NA	N	0,33	N	0,77	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5238	5238	C	A	MI.14368	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	769	257	L	M	Cta/Ata	-4,73	0	0	probably_damaging	1	neutral	0,23	neutral	4,3	neutral	-2,69	neutral	-1,92	medium_impact	2,13	neutral	0,91	damaging	0,21	deleterious	3,8	23,4	0,29	0,45	NA	NA	neutral	0,36	neutral	0,44	neutral	0,15	7	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	-0,08	medium_impact	0,65	0,63	0,8	NA	NA	N	0,43	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5239	5239	T	C	MI.14369	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	770	257	L	P	cTa/cCa	-0,11	0	0	probably_damaging	1	neutral	0,29	neutral	4,25	deleterious	-5,61	deleterious	-6,7	high_impact	3,78	neutral	0,82	damaging	0,11	deleterious	3,96	23,6	0,02	0,35	NA	NA	disease	0,77	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,01	high_impact	2,04	0,25	0,8	NA	NA	N	0,31	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9201	9201	C	A	MI.1437	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	675	225	N	K	aaC/aaA	6,84	1	0	probably_damaging	0,97	neutral	0,05	neutral	4,62	neutral	-0,72	deleterious	-5,13	low_impact	1,49	neutral	0,62	neutral	0,43	deleterious	4,58	24,4	0,73	0,75	NA	NA	neutral	0,41	disease	0,59	neutral	0,38	2	deleterious	0,99	neutral	0,04	neutral	-2	deleterious	0,75	low_impact	-2,19	medium_impact	-0,43	medium_impact	0,18	0,84	0,9	NA	NA	P	0,52	P	1	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5239	5239	T	G	MI.14370	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	770	257	L	R	cTa/cGa	-0,11	0	0	probably_damaging	1	neutral	0,29	neutral	4,26	deleterious	-5,03	deleterious	-5,74	high_impact	3,78	neutral	0,8	damaging	0,11	deleterious	4,24	23,9	0,02	0,35	NA	NA	disease	0,83	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	-0,01	high_impact	2,04	0,13	0,8	NA	NA	N	0,36	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5239	5239	T	A	MI.14371	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	770	257	L	Q	cTa/cAa	-0,11	0	0	probably_damaging	1	neutral	0,26	neutral	4,26	deleterious	-5,2	deleterious	-5,74	high_impact	3,78	neutral	0,86	damaging	0,14	deleterious	4,12	23,8	0,03	0,35	NA	NA	disease	0,73	disease	0,66	disease	0,65	3	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	-0,04	high_impact	2,04	0,29	0,8	NA	NA	N	0,34	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5241	5241	A	T	MI.14372	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	772	258	T	S	Acc/Tcc	-1,96	0	0	benign	0,18	neutral	0,43	neutral	4,68	neutral	2,08	neutral	-0,91	neutral_impact	0,63	neutral	0,9	neutral	0,88	neutral	-0,37	0,45	0,3	0,45	neutral	0,38	neutral	0,18	neutral	0,42	neutral	0,25	5	neutral	0,49	deleterious	0,63	neutral	-6	neutral	0,32	medium_impact	-0,19	medium_impact	0,14	medium_impact	-0,61	0,63	0,8	NA	NA	N	0,47	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5241	5241	A	G	MI.14373	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	772	258	T	A	Acc/Gcc	-1,96	0	0	possibly_damaging	0,62	neutral	0,52	neutral	4,7	neutral	2,43	deleterious	-2,64	low_impact	1,92	neutral	0,87	neutral	0,65	neutral	1,75	14,7	0,23	0,45	disease	0,51	disease	0,57	disease	0,6	disease	0,54	1	neutral	0,58	neutral	0,45	neutral	-3	deleterious	0,63	medium_impact	-0,99	medium_impact	0,23	medium_impact	0,47	0,31	0,8	NA	NA	N	0,3	N	0,75	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5241	5241	A	C	MI.14374	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	772	258	T	P	Acc/Ccc	-1,96	0	0	probably_damaging	0,95	neutral	0,22	neutral	4,52	neutral	-1,06	deleterious	-4,04	medium_impact	2,76	neutral	0,78	neutral	0,32	deleterious	3,33	22,9	0,05	0,35	disease	0,87	disease	0,84	disease	0,68	disease	0,65	3	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,8	low_impact	-1,97	medium_impact	-0,1	medium_impact	1,18	0,43	0,8	NA	NA	N	0,28	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5242	5242	C	T	MI.14375	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	773	258	T	I	aCc/aTc	0,13	0,01	0	probably_damaging	0,95	neutral	0,41	neutral	4,59	neutral	0,44	deleterious	-4,41	low_impact	1,61	neutral	0,85	neutral	0,47	deleterious	3,72	23,3	0,11	0,4	neutral	0,39	disease	0,79	disease	0,68	disease	0,66	3	neutral	0,95	neutral	0,23	neutral	-2	deleterious	0,71	low_impact	-1,97	medium_impact	0,12	medium_impact	0,21	0,58	0,8	NA	NA	N	0,27	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5242	5242	C	A	MI.14376	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	773	258	T	N	aCc/aAc	0,13	0,01	0	possibly_damaging	0,82	neutral	0,32	neutral	4,53	neutral	0,57	deleterious	-2,7	medium_impact	3,31	neutral	0,86	neutral	0,48	deleterious	2,11	16,92	0,22	0,45	disease	0,63	disease	0,79	disease	0,69	disease	0,66	3	neutral	0,84	neutral	0,25	NA	0	deleterious	0,73	low_impact	-1,4	medium_impact	0,03	medium_impact	1,64	0,49	0,8	NA	NA	N	0,32	N	0,76	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5242	5242	C	G	MI.14377	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	773	258	T	S	aCc/aGc	0,13	0,01	0	benign	0,18	neutral	0,43	neutral	4,68	neutral	2,08	neutral	-0,91	neutral_impact	0,63	neutral	0,9	neutral	0,88	neutral	-0,21	1,04	0,3	0,45	neutral	0,38	neutral	0,18	neutral	0,42	neutral	0,25	5	neutral	0,49	deleterious	0,63	neutral	-6	neutral	0,32	medium_impact	-0,19	medium_impact	0,14	medium_impact	-0,61	0,63	0,8	NA	NA	N	0,45	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5244	5244	G	T	MI.14378	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	775	259	G	C	Ggc/Tgc	-4,96	0	0	probably_damaging	1	neutral	0,18	neutral	4,21	deleterious	-7,72	deleterious	-8,62	high_impact	4,01	damaging	0,44	damaging	0,02	deleterious	4,21	23,9	0,03	0,35	disease	0,94	disease	0,9	disease	0,78	disease	0,64	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,54	medium_impact	-0,16	high_impact	2,23	0,24	0,8	NA	NA	N	0,43	N	0,96	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5244	5244	G	C	MI.14379	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	775	259	G	R	Ggc/Cgc	-4,96	0	0	probably_damaging	1	neutral	0,35	neutral	4,24	deleterious	-6,53	deleterious	-7,66	high_impact	4,01	damaging	0,51	damaging	0,02	deleterious	4,02	23,6	0,03	0,35	disease	0,68	disease	0,91	disease	0,86	disease	0,73	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-3,54	medium_impact	0,06	high_impact	2,23	0,66	0,8	NA	NA	N	0,37	N	1	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9201	9201	C	G	MI.1438	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	675	225	N	K	aaC/aaG	6,84	1	0	probably_damaging	0,97	neutral	0,05	neutral	4,62	neutral	-0,72	deleterious	-5,13	low_impact	1,49	neutral	0,62	neutral	0,43	deleterious	4,14	23,8	0,73	0,75	NA	NA	neutral	0,41	disease	0,59	neutral	0,38	2	deleterious	0,99	neutral	0,04	neutral	-2	deleterious	0,75	low_impact	-2,19	medium_impact	-0,43	medium_impact	0,18	0,84	0,9	NA	NA	P	0,52	P	1	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5244	5244	G	A	MI.14380	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	775	259	G	S	Ggc/Agc	-4,96	0	0	probably_damaging	1	neutral	0,4	neutral	4,31	deleterious	-5,14	deleterious	-5,75	high_impact	3,67	damaging	0,27	damaging	0,02	deleterious	4,23	23,9	0,05	0,35	disease	0,54	disease	0,85	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,11	medium_impact	1,95	0,7	0,85	NA	NA	P	0,77	P	0,98	disease_causing_automatic	0	0,18	rs199476115	Pathogenic	Leber's_optic_atrophy	RCV000010365.2	MedGen:OMIM:SNOMED_CT	.	.	.	.	G5244A	LHON	-	+	Reported	7
chrM	5245	5245	G	T	MI.14381	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	776	259	G	V	gGc/gTc	7,3	1	0	probably_damaging	1	neutral	0,5	neutral	4,23	deleterious	-5,08	deleterious	-8,62	high_impact	4,01	damaging	0,37	damaging	0,02	deleterious	3,86	23,5	0,03	0,35	disease	0,66	disease	0,91	disease	0,81	disease	0,72	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,21	high_impact	2,23	0,2	0,8	NA	NA	P	0,71	P	0,97	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5245	5245	G	A	MI.14382	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	776	259	G	D	gGc/gAc	7,3	1	0	probably_damaging	1	neutral	0,2	neutral	4,23	deleterious	-6,88	deleterious	-6,7	high_impact	4,01	damaging	0,48	damaging	0,02	deleterious	3,87	23,5	0,03	0,35	disease	0,62	disease	0,9	disease	0,85	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	-0,13	high_impact	2,23	0,21	0,8	NA	NA	P	0,64	P	0,95	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5245	5245	G	C	MI.14383	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	776	259	G	A	gGc/gCc	7,3	1	0	probably_damaging	1	neutral	0,51	neutral	4,26	deleterious	-5,23	deleterious	-5,75	high_impact	4,01	damaging	0,34	damaging	0,03	deleterious	3,21	22,7	0,06	0,35	disease	0,61	disease	0,77	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,22	high_impact	2,23	0,45	0,8	NA	NA	P	0,74	P	0,74	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5247	5247	T	C	MI.14384	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	778	260	F	L	Ttt/Ctt	-5,89	0	0	probably_damaging	1	neutral	0,67	neutral	3,51	deleterious	-7,35	deleterious	-5,75	medium_impact	3,31	damaging	0,57	damaging	0,05	deleterious	4,23	23,9	0,03	0,35	neutral	0,38	disease	0,81	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,38	medium_impact	1,64	0,54	0,8	NA	NA	N	0,39	N	0,91	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5247	5247	T	A	MI.14385	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	778	260	F	I	Ttt/Att	-5,89	0	0	probably_damaging	1	neutral	0,45	neutral	3,4	deleterious	-8,75	deleterious	-5,75	high_impact	4,01	damaging	0,6	damaging	0,06	deleterious	4,54	24,3	0,04	0,35	neutral	0,39	disease	0,82	disease	0,8	disease	0,68	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,16	high_impact	2,23	0,31	0,8	NA	NA	N	0,39	N	0,93	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5247	5247	T	G	MI.14386	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	778	260	F	V	Ttt/Gtt	-5,89	0	0	probably_damaging	1	neutral	0,4	neutral	3,4	deleterious	-8,63	deleterious	-6,7	high_impact	4,01	damaging	0,58	damaging	0,06	deleterious	4,24	23,9	0,04	0,35	neutral	0,38	disease	0,88	disease	0,81	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,11	high_impact	2,23	0,33	0,8	NA	NA	N	0,4	N	0,96	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5248	5248	T	G	MI.14387	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	779	260	F	C	tTt/tGt	7,3	1	0	probably_damaging	1	neutral	0,12	neutral	3,37	deleterious	-10,66	deleterious	-7,66	high_impact	4,01	damaging	0,6	damaging	0,05	deleterious	4,11	23,7	0,02	0,35	disease	0,89	disease	0,85	disease	0,82	disease	0,63	3	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	-0,27	high_impact	2,23	0,19	0,8	NA	NA	P	0,61	P	0,99	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5248	5248	T	C	MI.14388	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	779	260	F	S	tTt/tCt	7,3	1	0	probably_damaging	1	neutral	0,36	neutral	3,38	deleterious	-9,25	deleterious	-7,66	high_impact	3,66	damaging	0,5	damaging	0,07	deleterious	4,17	23,8	0,02	0,35	disease	0,68	disease	0,86	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,07	medium_impact	1,94	0,2	0,8	NA	NA	P	0,58	P	0,95	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5248	5248	T	A	MI.14389	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	779	260	F	Y	tTt/tAt	7,3	1	0	probably_damaging	1	neutral	0,71	neutral	3,47	deleterious	-5,93	deleterious	-2,87	high_impact	4,01	damaging	0,6	damaging	0,06	deleterious	4,23	23,9	0,08	0,35	disease	0,64	disease	0,8	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0,42	high_impact	2,23	0,4	0,8	NA	NA	P	0,64	P	0,88	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9202	9202	A	C	MI.1439	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	676	226	T	P	Aca/Cca	-1,95	0	0	benign	0,35	deleterious	0,01	neutral	4,48	neutral	-2,03	deleterious	-3,82	neutral_impact	0,78	neutral	0,81	damaging	0,23	deleterious	1,97	16,05	0,34	0,65	NA	NA	neutral	0,25	disease	0,67	neutral	0,31	4	deleterious	0,99	neutral	0,33	neutral	-2	deleterious	0,63	medium_impact	-0,5	medium_impact	-0,84	medium_impact	-0,43	0,68	0,9	NA	NA	N	0,32	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5249	5249	T	A	MI.14390	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	780	260	F	L	ttT/ttA	5,68	1	0	probably_damaging	1	neutral	0,67	neutral	3,51	deleterious	-7,35	deleterious	-5,75	medium_impact	3,31	damaging	0,57	damaging	0,05	deleterious	4,48	24,3	0,03	0,35	neutral	0,38	disease	0,81	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,38	medium_impact	1,64	0,54	0,8	NA	NA	P	0,55	P	0,91	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5249	5249	T	G	MI.14391	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	780	260	F	L	ttT/ttG	5,68	1	0	probably_damaging	1	neutral	0,67	neutral	3,51	deleterious	-7,35	deleterious	-5,75	medium_impact	3,31	damaging	0,57	damaging	0,05	deleterious	4,26	23,9	0,03	0,35	neutral	0,38	disease	0,81	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,38	medium_impact	1,64	0,54	0,8	NA	NA	P	0,55	P	0,91	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5250	5250	T	G	MI.14392	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	781	261	L	V	Ttg/Gtg	-2,88	0	0	benign	0,42	neutral	0,56	neutral	4,62	neutral	0,45	neutral	-1,22	low_impact	1,7	neutral	0,93	neutral	0,75	deleterious	2,3	18,19	0,33	0,5	disease	0,61	disease	0,52	neutral	0,41	neutral	0,26	5	neutral	0,4	deleterious	0,57	neutral	-6	deleterious	0,54	medium_impact	-0,67	medium_impact	0,27	medium_impact	0,29	0,49	0,8	5,48	8,08	N	0,26	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5250	5250	T	A	MI.14393	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	781	261	L	M	Ttg/Atg	-2,88	0	0	benign	0,3	neutral	0,6	neutral	4,46	neutral	-1,59	neutral	0,05	neutral_impact	0,01	neutral	0,95	neutral	0,92	deleterious	0,81	9,54	0,33	0,5	disease	0,61	neutral	0,06	neutral	0,27	neutral	0,29	4	neutral	0,31	deleterious	0,65	neutral	-6	neutral	0,38	medium_impact	-0,46	medium_impact	0,31	low_impact	-1,14	0,43	0,8	5,48	8,08	N	0,38	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5251	5251	T	G	MI.14394	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	782	261	L	W	tTg/tGg	-1,72	0	0	probably_damaging	0,96	neutral	0,18	neutral	4,41	neutral	-1,01	deleterious	-3,9	medium_impact	2,64	neutral	0,84	neutral	0,43	deleterious	3,78	23,4	0,06	0,35	disease	0,97	disease	0,74	disease	0,66	disease	0,75	5	neutral	0,98	neutral	0,11	deleterious	1	deleterious	0,81	low_impact	-2,06	medium_impact	-0,16	medium_impact	1,08	0,21	0,8	5,48	8,08	N	0,31	N	0,84	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5251	5251	T	C	MI.14395	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	782	261	L	S	tTg/tCg	-1,72	0	0	benign	0,1	neutral	0,44	neutral	4,42	neutral	-2,49	deleterious	-3,31	low_impact	1,12	neutral	0,9	neutral	0,86	deleterious	2,58	19,96	0,03	0,35	disease	0,86	disease	0,64	neutral	0,5	neutral	0,47	1	neutral	0,49	deleterious	0,67	neutral	-6	neutral	0,35	medium_impact	0,08	medium_impact	0,15	medium_impact	-0,2	0,33	0,8	5,48	8,08	N	0,34	N	0,64	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5252	5252	G	C	MI.14396	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	783	261	L	F	ttG/ttC	1,05	0	0,01	possibly_damaging	0,82	neutral	0,67	neutral	4,5	neutral	0,33	neutral	-2,24	low_impact	0,91	neutral	0,9	neutral	0,56	deleterious	3,54	23,1	0,29	0,45	disease	0,81	disease	0,62	disease	0,55	disease	0,65	3	neutral	0,79	neutral	0,43	neutral	-3	deleterious	0,73	low_impact	-1,4	medium_impact	0,38	medium_impact	-0,38	0,56	0,8	5,48	8,08	N	0,28	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5252	5252	G	T	MI.14397	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	783	261	L	F	ttG/ttT	1,05	0	0,01	possibly_damaging	0,82	neutral	0,67	neutral	4,5	neutral	0,33	neutral	-2,24	low_impact	0,91	neutral	0,9	neutral	0,56	deleterious	3,7	23,3	0,29	0,45	disease	0,81	disease	0,62	disease	0,55	disease	0,65	3	neutral	0,79	neutral	0,43	neutral	-3	deleterious	0,73	low_impact	-1,4	medium_impact	0,38	medium_impact	-0,38	0,56	0,8	5,48	8,08	N	0,28	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5253	5253	C	T	MI.14398	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	784	262	P	S	Ccc/Tcc	-3,34	0	0	probably_damaging	1	neutral	0,45	neutral	4,88	neutral	3,74	deleterious	-7,66	medium_impact	2,59	neutral	0,64	damaging	0,06	deleterious	3,99	23,6	0,17	0,45	disease	0,57	disease	0,8	disease	0,58	disease	0,65	3	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,16	medium_impact	1,04	0,29	0,8	NA	NA	N	0,31	N	0,72	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5253	5253	C	G	MI.14399	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	784	262	P	A	Ccc/Gcc	-3,34	0	0	probably_damaging	1	neutral	0,55	neutral	4,74	neutral	2,7	deleterious	-7,66	medium_impact	2,81	neutral	0,66	damaging	0,07	deleterious	3,2	22,7	0,11	0,4	neutral	0,39	disease	0,68	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,26	medium_impact	1,22	0,68	0,85	NA	NA	N	0,29	N	0,72	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8594	8594	T	C	MI.144	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	68	23	I	T	aTc/aCc	2,67	0,98	0	benign	0,39	neutral	0,43	neutral	4,3	neutral	-1,27	neutral	-2,2	neutral_impact	0,67	neutral	0,9	neutral	0,42	deleterious	0,34	6,05	0,5	0,65	disease	0,68	neutral	0,38	neutral	0,37	disease	0,63	3	neutral	0,5	deleterious	0,52	neutral	-6	deleterious	0,47	medium_impact	-0,57	medium_impact	0,22	medium_impact	-0,52	0,57	0,9	19,03	10,37	N	0,45	N	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9202	9202	A	G	MI.1440	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	676	226	T	A	Aca/Gca	-1,95	0	0	benign	0,09	deleterious	0,01	neutral	4,59	neutral	-0,05	deleterious	-2,66	low_impact	1,73	neutral	0,87	neutral	0,29	neutral	1,63	14,02	0,56	0,65	NA	NA	neutral	0,12	disease	0,64	neutral	0,25	5	deleterious	0,99	neutral	0,46	neutral	-2	neutral	0,2	medium_impact	0,2	medium_impact	-0,84	medium_impact	0,39	0,61	0,9	NA	NA	N	0,4	N	0,38	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5253	5253	C	A	MI.14400	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	784	262	P	T	Ccc/Acc	-3,34	0	0	probably_damaging	1	neutral	0,42	neutral	4,64	neutral	0,08	deleterious	-7,66	medium_impact	3,21	neutral	0,66	damaging	0,03	deleterious	3,8	23,4	0,09	0,35	neutral	0,5	disease	0,8	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,13	medium_impact	1,56	0,5	0,8	NA	NA	N	0,27	N	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5254	5254	C	A	MI.14401	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	785	262	P	H	cCc/cAc	4,06	0,98	0	probably_damaging	1	neutral	0,54	neutral	4,61	neutral	-2,23	deleterious	-8,62	high_impact	3,91	neutral	0,68	damaging	0,03	deleterious	4,07	23,7	0,06	0,35	disease	0,87	disease	0,85	disease	0,74	disease	0,62	2	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,25	high_impact	2,15	0,42	0,8	NA	NA	P	0,55	P	0,71	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5254	5254	C	T	MI.14402	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	785	262	P	L	cCc/cTc	4,06	0,98	0	probably_damaging	1	neutral	0,68	neutral	4,67	neutral	-1,14	deleterious	-9,57	medium_impact	2,81	neutral	0,66	damaging	0,03	deleterious	4,52	24,3	0,09	0,35	disease	0,52	disease	0,86	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,39	medium_impact	1,22	0,6	0,8	NA	NA	N	0,44	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5254	5254	C	G	MI.14403	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	785	262	P	R	cCc/cGc	4,06	0,98	0	probably_damaging	1	neutral	0,37	neutral	4,62	neutral	-1,19	deleterious	-8,62	high_impact	3,91	neutral	0,64	damaging	0,04	deleterious	3,68	23,3	0,04	0,35	disease	0,83	disease	0,89	disease	0,73	disease	0,67	3	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,08	high_impact	2,15	0,56	0,8	NA	NA	P	0,6	P	0,56	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5256	5256	A	G	MI.14404	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	787	263	K	E	Aaa/Gaa	-11,21	0	0	probably_damaging	1	neutral	0,92	neutral	4,12	neutral	-2,93	deleterious	-3,83	high_impact	4,01	neutral	0,74	damaging	0,07	deleterious	4,11	23,7	0,06	0,35	disease	0,84	disease	0,83	disease	0,78	disease	0,68	4	deleterious	1	neutral	0,46	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	0,8	high_impact	2,23	0,48	0,8	NA	NA	N	0,29	N	0,91	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5256	5256	A	C	MI.14405	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	787	263	K	Q	Aaa/Caa	-11,21	0	0	probably_damaging	1	neutral	0,68	neutral	3,84	deleterious	-6,11	deleterious	-3,83	high_impact	3,66	neutral	0,74	damaging	0,07	deleterious	3,49	23,1	0,08	0,35	neutral	0,4	disease	0,8	disease	0,75	disease	0,68	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,76	low_impact	-3,54	medium_impact	0,39	medium_impact	1,94	0,48	0,8	NA	NA	N	0,29	N	0,88	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5257	5257	A	C	MI.14406	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	788	263	K	T	aAa/aCa	8,45	1	0	probably_damaging	1	neutral	0,75	neutral	3,83	deleterious	-6,73	deleterious	-5,74	high_impact	4,01	neutral	0,73	damaging	0,07	deleterious	3,72	23,3	0,05	0,35	disease	0,52	disease	0,8	disease	0,79	disease	0,68	4	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	0,47	high_impact	2,23	0,25	0,8	NA	NA	P	0,59	P	0,81	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5257	5257	A	T	MI.14407	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	788	263	K	M	aAa/aTa	8,45	1	0	probably_damaging	1	neutral	0,3	neutral	3,8	deleterious	-8,57	deleterious	-5,74	high_impact	4,01	neutral	0,73	damaging	0,05	deleterious	4,08	23,7	0,04	0,35	disease	0,68	disease	0,8	disease	0,79	disease	0,68	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0	high_impact	2,23	0,26	0,8	NA	NA	P	0,63	P	0,45	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5258	5258	A	T	MI.14408	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	789	263	K	N	aaA/aaT	8,45	1	0	probably_damaging	1	neutral	0,64	neutral	3,84	deleterious	-6,37	deleterious	-4,78	high_impact	4,01	neutral	0,71	damaging	0,05	deleterious	4,03	23,6	0,07	0,35	disease	0,84	disease	0,82	disease	0,79	disease	0,66	3	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,35	high_impact	2,23	0,38	0,8	NA	NA	P	0,64	P	0,69	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5258	5258	A	C	MI.14409	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	789	263	K	N	aaA/aaC	8,45	1	0	probably_damaging	1	neutral	0,64	neutral	3,84	deleterious	-6,37	deleterious	-4,78	high_impact	4,01	neutral	0,71	damaging	0,05	deleterious	3,99	23,6	0,07	0,35	disease	0,84	disease	0,82	disease	0,79	disease	0,66	3	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,35	high_impact	2,23	0,38	0,8	NA	NA	P	0,63	P	0,69	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9202	9202	A	T	MI.1441	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	676	226	T	S	Aca/Tca	-1,95	0	0	benign	0,01	neutral	0,32	neutral	4,56	neutral	-0,37	neutral	-2,25	low_impact	1	neutral	0,95	neutral	0,75	deleterious	0,09	3,52	0,57	0,65	NA	NA	neutral	0,06	neutral	0,47	neutral	0,16	7	neutral	0,67	deleterious	0,66	neutral	-6	neutral	0,08	medium_impact	1,14	medium_impact	0,11	medium_impact	-0,24	0,8	0,9	NA	NA	N	0,45	N	0,02	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5259	5259	T	G	MI.14410	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	790	264	W	G	Tgg/Ggg	2,67	1	0	probably_damaging	0,94	neutral	0,23	neutral	4,59	neutral	-2,46	deleterious	-12,41	high_impact	3,86	neutral	0,91	damaging	0,12	deleterious	4,04	23,7	0,04	0,35	disease	0,86	disease	0,87	disease	0,75	disease	0,63	3	neutral	0,96	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-1,89	medium_impact	-0,08	high_impact	2,11	0,16	0,8	NA	NA	P	0,59	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5259	5259	T	C	MI.14411	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	790	264	W	R	Tgg/Cgg	2,67	1	0	probably_damaging	0,99	neutral	0,2	neutral	4,6	neutral	-2,35	deleterious	-13,37	high_impact	3,86	neutral	0,79	damaging	0,09	deleterious	3,73	23,3	0,03	0,35	disease	0,59	disease	0,93	disease	0,79	disease	0,74	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-2,62	medium_impact	-0,13	high_impact	2,11	0,21	0,8	NA	NA	P	0,56	P	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5260	5260	G	C	MI.14412	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	791	264	W	S	tGg/tCg	5,68	1	0	probably_damaging	0,97	neutral	0,29	neutral	4,62	neutral	-1,45	deleterious	-13,36	high_impact	3,86	neutral	0,81	damaging	0,12	deleterious	4,12	23,8	0,04	0,35	disease	0,72	disease	0,93	disease	0,73	disease	0,72	4	neutral	0,98	neutral	0,16	deleterious	2	deleterious	0,86	low_impact	-2,18	medium_impact	-0,01	high_impact	2,11	0,17	0,8	NA	NA	P	0,58	P	0,94	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5260	5260	G	T	MI.14413	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	791	264	W	L	tGg/tTg	5,68	1	0	possibly_damaging	0,77	neutral	1	neutral	4,77	neutral	1,36	deleterious	-12,41	low_impact	1,6	neutral	0,79	damaging	0,08	deleterious	4,34	24	0,09	0,35	disease	0,59	disease	0,85	disease	0,67	neutral	0,39	2	neutral	0,77	deleterious	0,62	neutral	-3	deleterious	0,73	low_impact	-1,28	high_impact	1,87	medium_impact	0,2	0,15	0,8	NA	NA	N	0,42	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5261	5261	G	C	MI.14414	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	792	264	W	C	tgG/tgC	7,07	1	0,02	probably_damaging	0,99	neutral	0,12	neutral	4,58	deleterious	-3,02	deleterious	-12,41	high_impact	3,52	neutral	0,77	damaging	0,08	deleterious	4,1	23,7	0,04	0,35	disease	0,74	disease	0,91	disease	0,77	disease	0,7	4	deleterious	0,99	neutral	0,07	deleterious	2	deleterious	0,84	low_impact	-2,62	medium_impact	-0,27	medium_impact	1,82	0,26	0,8	NA	NA	P	0,56	P	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5261	5261	G	T	MI.14415	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	792	264	W	C	tgG/tgT	7,07	1	0,02	probably_damaging	0,99	neutral	0,12	neutral	4,58	deleterious	-3,02	deleterious	-12,41	high_impact	3,52	neutral	0,77	damaging	0,08	deleterious	4,26	23,9	0,04	0,35	disease	0,74	disease	0,91	disease	0,77	disease	0,7	4	deleterious	0,99	neutral	0,07	deleterious	2	deleterious	0,84	low_impact	-2,62	medium_impact	-0,27	medium_impact	1,82	0,26	0,8	NA	NA	P	0,57	P	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5262	5262	G	T	MI.14416	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	793	265	A	S	Gcc/Tcc	1,28	0,5	0	benign	0,06	neutral	0,3	neutral	4,62	neutral	-1,6	neutral	-0,58	neutral_impact	0,2	neutral	0,84	neutral	0,64	deleterious	1,94	15,85	0,23	0,45	disease	0,54	neutral	0,44	neutral	0,43	disease	0,51	0	neutral	0,67	deleterious	0,62	neutral	-6	neutral	0,23	medium_impact	0,3	medium_impact	0	medium_impact	-0,98	0,57	0,8	2,59	8,19	N	0,35	N	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5262	5262	G	C	MI.14417	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	793	265	A	P	Gcc/Ccc	1,28	0,5	0	benign	0,3	neutral	0,08	neutral	4,57	deleterious	-3,71	neutral	-1,62	neutral_impact	0,55	neutral	0,74	neutral	0,38	deleterious	2,2	17,52	0,04	0,35	disease	0,92	disease	0,82	disease	0,6	disease	0,69	4	neutral	0,91	neutral	0,39	neutral	-6	deleterious	0,55	medium_impact	-0,46	medium_impact	-0,38	medium_impact	-0,68	0,66	0,8	2,59	8,19	N	0,29	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5262	5262	G	A	MI.14418	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	793	265	A	T	Gcc/Acc	1,28	0,5	0	benign	0,01	neutral	0,2	neutral	4,63	neutral	-1,38	neutral	-0,36	neutral_impact	-0,18	neutral	0,99	neutral	0,88	deleterious	2,33	18,39	0,17	0,45	disease	0,73	neutral	0,4	neutral	0,45	disease	0,65	3	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,19	medium_impact	1,03	medium_impact	-0,13	low_impact	-1,3	0,76	0,85	2,59	8,19	N	0,44	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5263	5263	C	T	MI.14419	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	794	265	A	V	gCc/gTc	-1,26	0	0,04	benign	0	neutral	0,25	neutral	4,66	neutral	-0,85	neutral	1,63	neutral_impact	-0,32	neutral	0,99	neutral	0,96	neutral	1,47	13,13	0,16	0,45	disease	0,65	neutral	0,46	neutral	0,41	disease	0,62	2	neutral	0,75	deleterious	0,63	neutral	-6	neutral	0,18	medium_impact	1,95	medium_impact	-0,06	low_impact	-1,41	0,73	0,85	2,59	8,19	N	0,35	N	0	polymorphism	1	0,01	rs41320049	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9203	9203	C	A	MI.1442	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	677	226	T	K	aCa/aAa	0,59	0	0	benign	0,14	deleterious	0,01	neutral	4,52	neutral	-0,86	deleterious	-3,85	medium_impact	2,62	neutral	0,88	damaging	0,26	deleterious	2,83	21,5	0,37	0,65	NA	NA	neutral	0,29	disease	0,67	neutral	0,32	4	deleterious	0,99	neutral	0,44	deleterious	1	neutral	0,33	medium_impact	-0,01	medium_impact	-0,84	medium_impact	1,15	0,63	0,9	NA	NA	N	0,39	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5263	5263	C	G	MI.14420	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	794	265	A	G	gCc/gGc	-1,26	0	0,04	benign	0,16	neutral	0,12	neutral	4,58	neutral	-2,25	neutral	-2,36	neutral_impact	0,06	neutral	0,88	neutral	0,59	deleterious	2,14	17,13	0,19	0,45	disease	0,54	neutral	0,44	neutral	0,43	disease	0,51	0	neutral	0,86	deleterious	0,48	neutral	-6	neutral	0,24	medium_impact	-0,14	medium_impact	-0,27	low_impact	-1,09	0,66	0,8	2,59	8,19	N	0,44	N	0,49	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5263	5263	C	A	MI.14421	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	794	265	A	D	gCc/gAc	-1,26	0	0,04	benign	0,3	deleterious	0,04	neutral	4,56	deleterious	-4,22	neutral	-2,42	low_impact	1,1	neutral	0,85	neutral	0,46	deleterious	2,74	21	0,02	0,35	disease	0,94	disease	0,73	disease	0,59	disease	0,73	5	neutral	0,95	neutral	0,37	neutral	-2	deleterious	0,52	medium_impact	-0,46	medium_impact	-0,56	medium_impact	-0,22	0,39	0,8	2,59	8,19	N	0,31	N	0,56	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5265	5265	A	C	MI.14422	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	796	266	I	L	Att/Ctt	-6,35	0	0	benign	0,08	neutral	0,91	neutral	4,57	neutral	-0,47	neutral	-1,79	medium_impact	2,48	neutral	0,85	neutral	0,47	deleterious	2,04	16,45	0,16	0,45	neutral	0,46	disease	0,77	disease	0,55	disease	0,64	3	neutral	0,03	deleterious	0,92	neutral	-3	neutral	0,34	medium_impact	0,17	medium_impact	0,77	medium_impact	0,94	0,55	0,8	0,86	7,31	N	0,18	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5265	5265	A	T	MI.14423	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	796	266	I	F	Att/Ttt	-6,35	0	0	possibly_damaging	0,57	neutral	0,38	neutral	4,31	neutral	-2,81	deleterious	-3,64	medium_impact	3,42	neutral	0,93	neutral	0,47	deleterious	3,86	23,5	0,05	0,35	disease	0,79	disease	0,86	disease	0,63	disease	0,67	3	neutral	0,64	neutral	0,41	NA	0	deleterious	0,76	medium_impact	-0,91	medium_impact	0,09	medium_impact	1,73	0,54	0,8	0,86	7,31	N	0,41	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5265	5265	A	G	MI.14424	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	796	266	I	V	Att/Gtt	-6,35	0	0	benign	0,01	neutral	0,35	neutral	4,59	neutral	-0,24	neutral	-0,81	low_impact	1,45	neutral	0,88	neutral	0,7	neutral	1,17	11,61	0,35	0,5	disease	0,54	disease	0,53	neutral	0,5	neutral	0,24	5	neutral	0,64	deleterious	0,67	neutral	-6	neutral	0,2	medium_impact	1,03	medium_impact	0,06	medium_impact	0,08	0,4	0,8	0,86	7,31	N	0,31	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5266	5266	T	C	MI.14425	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	797	266	I	T	aTt/aCt	4,75	0,99	0	benign	0,01	neutral	0,18	neutral	4,34	deleterious	-3,32	deleterious	-4,08	medium_impact	2,12	neutral	0,84	neutral	0,62	deleterious	0,7	8,86	0,03	0,35	disease	0,66	disease	0,83	disease	0,56	neutral	0,29	4	neutral	0,82	deleterious	0,59	neutral	-3	neutral	0,3	medium_impact	1,03	medium_impact	-0,16	medium_impact	0,64	0,28	0,8	0,86	7,31	N	0,51	P	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5266	5266	T	A	MI.14426	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	797	266	I	N	aTt/aAt	4,75	0,99	0	possibly_damaging	0,57	neutral	0,27	neutral	4,28	deleterious	-5,33	deleterious	-6,19	high_impact	3,77	neutral	0,87	neutral	0,47	deleterious	4,41	24,1	0,03	0,35	disease	0,82	disease	0,92	disease	0,63	disease	0,66	3	neutral	0,73	neutral	0,35	deleterious	1	deleterious	0,77	medium_impact	-0,91	medium_impact	-0,03	high_impact	2,03	0,36	0,8	0,86	7,31	P	0,65	P	1	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5266	5266	T	G	MI.14427	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	797	266	I	S	aTt/aGt	4,75	0,99	0	benign	0,29	neutral	0,32	neutral	4,35	deleterious	-3,82	deleterious	-5,24	medium_impact	2,44	neutral	0,87	neutral	0,58	deleterious	4,03	23,6	0,02	0,35	neutral	0,46	disease	0,91	disease	0,6	disease	0,69	4	neutral	0,61	deleterious	0,52	neutral	-3	deleterious	0,56	medium_impact	-0,44	medium_impact	0,03	medium_impact	0,91	0,4	0,8	0,86	7,31	P	0,57	P	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5267	5267	T	A	MI.14428	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	798	266	I	M	atT/atA	2,9	0,99	0	possibly_damaging	0,75	neutral	0,28	neutral	4,31	deleterious	-3,03	deleterious	-2,67	medium_impact	2,57	neutral	0,94	neutral	0,57	deleterious	3,62	23,2	0,08	0,35	disease	0,7	disease	0,76	disease	0,55	disease	0,64	3	neutral	0,81	neutral	0,27	NA	0	deleterious	0,71	low_impact	-1,23	medium_impact	-0,02	medium_impact	1,02	0,49	0,8	0,86	7,31	P	0,57	P	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5267	5267	T	G	MI.14429	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	798	266	I	M	atT/atG	2,9	0,99	0	possibly_damaging	0,75	neutral	0,28	neutral	4,31	deleterious	-3,03	deleterious	-2,67	medium_impact	2,57	neutral	0,94	neutral	0,57	deleterious	3,29	22,8	0,08	0,35	disease	0,7	disease	0,76	disease	0,55	disease	0,64	3	neutral	0,81	neutral	0,27	NA	0	deleterious	0,71	low_impact	-1,23	medium_impact	-0,02	medium_impact	1,02	0,49	0,8	0,86	7,31	N	0,56	P	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9203	9203	C	T	MI.1443	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	677	226	T	M	aCa/aTa	0,59	0	0	possibly_damaging	0,78	deleterious	0	neutral	4,47	neutral	-2,16	deleterious	-3,41	medium_impact	2,27	neutral	0,89	damaging	0,26	deleterious	4,03	23,6	0,38	0,65	NA	NA	neutral	0,21	disease	0,69	neutral	0,35	3	deleterious	1	neutral	0,11	deleterious	4	deleterious	0,77	low_impact	-1,28	low_impact	-1,4	medium_impact	0,85	0,76	0,9	NA	NA	N	0,44	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5268	5268	A	G	MI.14430	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	799	267	I	V	Atc/Gtc	-7,05	0	0	benign	0,36	neutral	0,38	neutral	4,34	neutral	-2,77	neutral	-0,87	medium_impact	2,23	neutral	0,93	neutral	0,75	deleterious	3,13	22,6	0,48	0,55	disease	0,55	neutral	0,47	neutral	0,48	disease	0,59	2	neutral	0,55	deleterious	0,51	neutral	-3	deleterious	0,49	medium_impact	-0,57	medium_impact	0,09	medium_impact	0,73	0,44	0,8	1,15	8,18	N	0,36	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5268	5268	A	C	MI.14431	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	799	267	I	L	Atc/Ctc	-7,05	0	0	benign	0,02	neutral	1	neutral	5,36	neutral	1,96	neutral	-1,59	neutral_impact	0,45	neutral	0,89	neutral	0,9	deleterious	2,26	17,9	0,25	0,45	neutral	0,44	neutral	0,23	neutral	0,23	neutral	0,46	1	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,16	medium_impact	0,75	high_impact	1,87	medium_impact	-0,77	0,5	0,8	1,15	8,18	N	0,37	N	0,37	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5268	5268	A	T	MI.14432	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	799	267	I	F	Atc/Ttc	-7,05	0	0	possibly_damaging	0,78	neutral	0,47	neutral	4,45	neutral	-1,26	deleterious	-3,58	medium_impact	2,15	neutral	0,9	neutral	0,47	deleterious	3,87	23,5	0,08	0,35	disease	0,62	disease	0,82	disease	0,58	disease	0,67	3	neutral	0,77	neutral	0,35	NA	0	deleterious	0,74	low_impact	-1,3	medium_impact	0,18	medium_impact	0,67	0,48	0,8	1,15	8,18	N	0,36	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5269	5269	T	G	MI.14433	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	800	267	I	S	aTc/aGc	0,82	0,27	0	possibly_damaging	0,87	neutral	0,34	neutral	4,29	deleterious	-5,8	deleterious	-5,42	medium_impact	2,96	neutral	0,88	neutral	0,48	deleterious	4,34	24	0,02	0,35	disease	0,89	disease	0,87	disease	0,58	disease	0,69	4	neutral	0,88	neutral	0,24	NA	0	deleterious	0,83	low_impact	-1,55	medium_impact	0,05	medium_impact	1,35	0,18	0,8	1,15	8,18	N	0,42	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5269	5269	T	C	MI.14434	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	800	267	I	T	aTc/aCc	0,82	0,27	0	possibly_damaging	0,74	neutral	0,25	neutral	4,3	deleterious	-4,86	deleterious	-4,5	medium_impact	2,54	neutral	0,92	neutral	0,57	deleterious	3,48	23,1	0,02	0,35	disease	0,85	disease	0,76	disease	0,53	disease	0,6	2	neutral	0,82	neutral	0,26	NA	0	deleterious	0,78	low_impact	-1,21	medium_impact	-0,06	medium_impact	0,99	0,23	0,8	1,15	8,18	N	0,45	N	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5269	5269	T	A	MI.14435	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	800	267	I	N	aTc/aAc	0,82	0,27	0	probably_damaging	0,96	neutral	0,28	neutral	4,29	deleterious	-6,92	deleterious	-6,38	high_impact	3,51	neutral	0,89	neutral	0,44	deleterious	4,46	24,2	0,03	0,35	disease	0,95	disease	0,9	disease	0,59	disease	0,73	5	neutral	0,96	neutral	0,16	deleterious	2	deleterious	0,86	low_impact	-2,06	medium_impact	-0,02	medium_impact	1,81	0,15	0,8	1,15	8,18	N	0,45	N	0,97	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5270	5270	C	G	MI.14436	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	801	267	I	M	atC/atG	4,29	0,7	0	benign	0,12	neutral	0,25	neutral	4,35	neutral	-2,53	neutral	-2,4	medium_impact	2,19	neutral	0,92	neutral	0,86	deleterious	3,38	23	0,09	0,4	disease	0,8	disease	0,61	neutral	0,48	disease	0,5	0	neutral	0,71	deleterious	0,57	neutral	-3	neutral	0,41	medium_impact	-0,01	medium_impact	-0,06	medium_impact	0,7	0,46	0,8	1,15	8,18	N	0,42	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5270	5270	C	A	MI.14437	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	801	267	I	M	atC/atA	4,29	0,7	0	benign	0,12	neutral	0,25	neutral	4,35	neutral	-2,53	neutral	-2,4	medium_impact	2,19	neutral	0,92	neutral	0,86	deleterious	3,85	23,4	0,09	0,4	disease	0,8	disease	0,61	neutral	0,48	disease	0,5	0	neutral	0,71	deleterious	0,57	neutral	-3	neutral	0,41	medium_impact	-0,01	medium_impact	-0,06	medium_impact	0,7	0,46	0,8	1,15	8,18	N	0,43	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5271	5271	G	C	MI.14438	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	802	268	E	Q	Gaa/Caa	-8,66	0	0	benign	0,01	neutral	0,34	neutral	4,54	neutral	-0,37	neutral	1,74	neutral_impact	-1,76	neutral	0,9	neutral	0,94	deleterious	0,47	7,22	0,24	0,45	neutral	0,36	neutral	0,05	neutral	0,12	neutral	0,22	6	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,14	medium_impact	1,03	medium_impact	0,05	low_impact	-2,63	0,63	0,8	6,92	8,54	N	0,51	P	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5271	5271	G	A	MI.14439	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	802	268	E	K	Gaa/Aaa	-8,66	0	0	benign	0,14	neutral	0,32	neutral	4,53	neutral	-0,8	neutral	-0,75	neutral_impact	-0,24	neutral	0,86	neutral	0,72	deleterious	1,94	15,81	0,07	0,35	neutral	0,49	disease	0,7	neutral	0,29	neutral	0,19	6	neutral	0,63	deleterious	0,59	neutral	-6	neutral	0,38	medium_impact	-0,08	medium_impact	0,03	low_impact	-1,35	0,7	0,85	6,92	8,54	N	0,31	N	0,5	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8366	8366	A	C	MI.1444	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	1	1	M	L	Atg/Ctg	-9,59	0	0	possibly_damaging	0,66	deleterious	0	deleterious	-2,11	deleterious	-10,1	deleterious	-2,98	NA	NA	neutral	0,89	damaging	0,07	deleterious	2,74	21,1	0,2269091	0,85	neutral	0,36	neutral	0,11	disease	0,71	neutral	0,19	6	deleterious	1	neutral	0,17	deleterious	3	neutral	0,42	NA	NA	NA	NA	NA	NA	0,35	0,85	20,59	8,49	N	0,44	N	0,67	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5272	5272	A	T	MI.14440	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	803	268	E	V	gAa/gTa	0,36	0,04	0	benign	0,14	neutral	0,52	neutral	4,54	neutral	-1,5	deleterious	-3,74	neutral_impact	0,64	neutral	0,88	neutral	0,67	deleterious	4,14	23,8	0,09	0,35	disease	0,73	disease	0,69	neutral	0,49	neutral	0,48	0	neutral	0,39	deleterious	0,69	neutral	-6	neutral	0,41	medium_impact	-0,08	medium_impact	0,23	medium_impact	-0,61	0,28	0,8	6,92	8,54	N	0,29	N	0,65	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5272	5272	A	G	MI.14441	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	803	268	E	G	gAa/gGa	0,36	0,04	0	benign	0,01	neutral	0,34	neutral	4,52	neutral	-1,41	deleterious	-3,34	low_impact	1,38	neutral	0,9	neutral	0,56	deleterious	2,44	19,07	0,12	0,4	neutral	0,46	disease	0,55	disease	0,51	disease	0,52	0	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,21	medium_impact	1,03	medium_impact	0,05	medium_impact	0,02	0,27	0,8	6,92	8,54	N	0,44	N	0,56	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5272	5272	A	C	MI.14442	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	803	268	E	A	gAa/gCa	0,36	0,04	0	benign	0,14	neutral	0,52	neutral	4,59	neutral	-0,55	deleterious	-2,8	low_impact	1,04	neutral	0,89	neutral	0,72	deleterious	2,14	17,1	0,11	0,4	neutral	0,48	neutral	0,46	neutral	0,48	neutral	0,4	2	neutral	0,39	deleterious	0,69	neutral	-6	neutral	0,34	medium_impact	-0,08	medium_impact	0,23	medium_impact	-0,27	0,35	0,8	6,92	8,54	N	0,34	N	0,32	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5273	5273	A	C	MI.14443	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	804	268	E	D	gaA/gaC	4,52	0,98	0	benign	0,18	neutral	0,22	neutral	4,5	neutral	-1,7	neutral	-1,27	neutral_impact	0,7	neutral	0,86	neutral	0,77	deleterious	2,16	17,24	0,3	0,45	disease	0,59	disease	0,51	neutral	0,32	neutral	0,36	3	neutral	0,74	deleterious	0,52	neutral	-6	deleterious	0,44	medium_impact	-0,19	medium_impact	-0,1	medium_impact	-0,56	0,58	0,8	6,92	8,54	P	0,57	P	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5273	5273	A	T	MI.14444	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	804	268	E	D	gaA/gaT	4,52	0,98	0	benign	0,18	neutral	0,22	neutral	4,5	neutral	-1,7	neutral	-1,27	neutral_impact	0,7	neutral	0,86	neutral	0,77	deleterious	2,28	18,02	0,3	0,45	disease	0,59	disease	0,51	neutral	0,32	neutral	0,36	3	neutral	0,74	deleterious	0,52	neutral	-6	deleterious	0,44	medium_impact	-0,19	medium_impact	-0,1	medium_impact	-0,56	0,58	0,8	6,92	8,54	P	0,59	P	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5274	5274	G	C	MI.14445	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	805	269	E	Q	Gaa/Caa	0,36	0,97	0	probably_damaging	1	neutral	0,3	neutral	4,14	neutral	-1,05	deleterious	-2,87	medium_impact	2,08	neutral	0,87	damaging	0,14	deleterious	3,44	23	0,19	0,45	disease	0,82	disease	0,81	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0	medium_impact	0,61	0,48	0,8	NA	NA	N	0,39	N	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5274	5274	G	A	MI.14446	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	805	269	E	K	Gaa/Aaa	0,36	0,97	0	probably_damaging	1	neutral	0,31	neutral	4,15	neutral	-0,72	deleterious	-3,83	medium_impact	2,27	neutral	0,88	damaging	0,12	deleterious	4,56	24,4	0,08	0,35	disease	0,8	disease	0,91	disease	0,6	disease	0,64	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,89	low_impact	-3,54	medium_impact	0,02	medium_impact	0,77	0,53	0,8	NA	NA	N	0,43	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5275	5275	A	C	MI.14447	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	806	269	E	A	gAa/gCa	4,98	1	0	probably_damaging	1	neutral	0,52	neutral	4,45	neutral	1,92	deleterious	-5,74	medium_impact	2,3	neutral	0,88	damaging	0,15	deleterious	3,65	23,2	0,13	0,4	neutral	0,41	disease	0,77	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,23	medium_impact	0,79	0,29	0,8	NA	NA	N	0,45	N	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5275	5275	A	G	MI.14448	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	806	269	E	G	gAa/gGa	4,98	1	0	probably_damaging	1	neutral	0,35	neutral	4,2	neutral	0,25	deleterious	-6,7	medium_impact	2,52	neutral	0,93	damaging	0,18	deleterious	4,18	23,8	0,14	0,4	disease	0,83	disease	0,82	disease	0,62	disease	0,63	3	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,06	medium_impact	0,98	0,19	0,8	NA	NA	N	0,54	P	0,46	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5275	5275	A	T	MI.14449	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	806	269	E	V	gAa/gTa	4,98	1	0	probably_damaging	1	neutral	0,51	neutral	4,11	neutral	-1,69	deleterious	-6,7	medium_impact	2,3	neutral	0,84	damaging	0,13	deleterious	4,11	23,7	0,08	0,35	neutral	0,37	disease	0,9	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	0,22	medium_impact	0,79	0,29	0,8	NA	NA	N	0,43	N	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8366	8366	A	T	MI.1445	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	1	1	M	L	Atg/Ttg	-9,59	0	0	possibly_damaging	0,66	deleterious	0	deleterious	-2,11	deleterious	-10,1	deleterious	-2,98	NA	NA	neutral	0,89	damaging	0,07	deleterious	2,75	21,1	0,2269091	0,85	neutral	0,36	neutral	0,11	disease	0,71	neutral	0,19	6	deleterious	1	neutral	0,17	deleterious	3	neutral	0,42	NA	NA	NA	NA	NA	NA	0,35	0,85	20,59	8,49	N	0,45	N	0,67	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5276	5276	A	C	MI.14450	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	807	269	E	D	gaA/gaC	6,37	1	0	probably_damaging	1	neutral	0,21	neutral	4,12	neutral	-1,56	deleterious	-2,87	medium_impact	2,34	neutral	0,9	damaging	0,19	deleterious	3,72	23,3	0,23	0,45	disease	0,88	disease	0,76	neutral	0,49	disease	0,53	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	-0,11	medium_impact	0,83	0,56	0,8	NA	NA	P	0,63	P	0,85	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5276	5276	A	T	MI.14451	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	807	269	E	D	gaA/gaT	6,37	1	0	probably_damaging	1	neutral	0,21	neutral	4,12	neutral	-1,56	deleterious	-2,87	medium_impact	2,34	neutral	0,9	damaging	0,19	deleterious	3,83	23,4	0,23	0,45	disease	0,88	disease	0,76	neutral	0,49	disease	0,53	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	-0,11	medium_impact	0,83	0,56	0,8	NA	NA	P	0,64	P	0,85	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5277	5277	T	A	MI.14452	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	808	270	F	I	Ttc/Atc	0,13	0	0	benign	0,01	neutral	0,38	neutral	4,22	neutral	-0,77	neutral	1,47	neutral_impact	-0,6	neutral	0,9	neutral	0,94	deleterious	2,77	21,2	0,16	0,45	neutral	0,39	neutral	0,41	neutral	0,2	neutral	0,44	1	neutral	0,61	deleterious	0,69	neutral	-6	neutral	0,18	medium_impact	1,03	medium_impact	0,09	low_impact	-1,65	0,57	0,8	0,29	8,23	N	0,4	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5277	5277	T	G	MI.14453	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	808	270	F	V	Ttc/Gtc	0,13	0	0	benign	0,04	neutral	0,39	neutral	4,26	neutral	-0,03	neutral	0,71	neutral_impact	-0,3	neutral	0,93	neutral	0,75	deleterious	2,4	18,85	0,09	0,35	neutral	0,37	disease	0,55	neutral	0,36	neutral	0,43	1	neutral	0,58	deleterious	0,68	neutral	-6	neutral	0,22	medium_impact	0,47	medium_impact	0,1	low_impact	-1,4	0,4	0,8	0,29	8,23	N	0,32	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5277	5277	T	C	MI.14454	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	808	270	F	L	Ttc/Ctc	0,13	0	0	benign	0	neutral	1	neutral	4,41	neutral	0,54	neutral	2,96	neutral_impact	-2,67	neutral	0,91	neutral	0,95	neutral	-0,37	0,45	0,21	0,45	disease	0,57	neutral	0,12	neutral	0,15	neutral	0,33	3	neutral	0	deleterious	1	neutral	-6	neutral	0,13	medium_impact	1,95	high_impact	1,87	low_impact	-3,39	0,75	0,85	0,29	8,23	N	0,28	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5278	5278	T	A	MI.14455	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	809	270	F	Y	tTc/tAc	-2,19	0	0	benign	0,41	neutral	0,56	neutral	4,15	neutral	-2,05	neutral	-1,04	neutral_impact	-0,14	neutral	0,91	neutral	0,57	deleterious	2,79	21,3	0,14	0,4	disease	0,83	neutral	0,43	neutral	0,48	disease	0,65	3	neutral	0,4	deleterious	0,58	neutral	-6	deleterious	0,61	medium_impact	-0,65	medium_impact	0,27	low_impact	-1,26	0,7	0,85	0,29	8,23	N	0,33	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5278	5278	T	C	MI.14456	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	809	270	F	S	tTc/tCc	-2,19	0	0	benign	0,41	neutral	0,44	neutral	4,19	neutral	-1,42	neutral	-1,95	neutral_impact	-0,55	neutral	0,82	neutral	0,54	deleterious	2,71	20,9	0,04	0,35	disease	0,78	disease	0,53	disease	0,52	disease	0,53	1	neutral	0,5	deleterious	0,52	neutral	-6	deleterious	0,62	medium_impact	-0,65	medium_impact	0,15	low_impact	-1,61	0,25	0,8	0,29	8,23	N	0,27	N	0,69	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5278	5278	T	G	MI.14457	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	809	270	F	C	tTc/tGc	-2,19	0	0	possibly_damaging	0,85	neutral	0,07	neutral	4,13	neutral	-2,97	neutral	-1,24	neutral_impact	0,2	neutral	0,84	neutral	0,43	deleterious	4,07	23,7	0,04	0,35	disease	0,89	disease	0,6	neutral	0,5	disease	0,54	1	neutral	0,96	neutral	0,11	neutral	-3	deleterious	0,75	low_impact	-1,49	medium_impact	-0,42	medium_impact	-0,98	0,18	0,8	0,29	8,23	N	0,35	N	0,64	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5279	5279	C	A	MI.14458	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	810	270	F	L	ttC/ttA	7,3	0,94	0	benign	0	neutral	1	neutral	4,41	neutral	0,54	neutral	2,96	neutral_impact	-2,67	neutral	0,91	neutral	0,95	deleterious	0,03	2,86	0,21	0,45	disease	0,57	neutral	0,12	neutral	0,15	neutral	0,33	3	neutral	0	deleterious	1	neutral	-6	neutral	0,13	medium_impact	1,95	high_impact	1,87	low_impact	-3,39	0,75	0,85	0,29	8,23	N	0,41	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5279	5279	C	G	MI.14459	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	810	270	F	L	ttC/ttG	7,3	0,94	0	benign	0	neutral	1	neutral	4,41	neutral	0,54	neutral	2,96	neutral_impact	-2,67	neutral	0,91	neutral	0,95	neutral	-0,26	0,82	0,21	0,45	disease	0,57	neutral	0,12	neutral	0,15	neutral	0,33	3	neutral	0	deleterious	1	neutral	-6	neutral	0,13	medium_impact	1,95	high_impact	1,87	low_impact	-3,39	0,75	0,85	0,29	8,23	N	0,41	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8366	8366	A	G	MI.1446	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	1	1	M	V	Atg/Gtg	-9,59	0	0	possibly_damaging	0,75	deleterious	0	deleterious	-2,12	deleterious	-11,65	deleterious	-3,97	NA	NA	neutral	0,84	damaging	0,09	deleterious	2,1	16,83	0,29828471	0,85	disease	0,54	neutral	0,09	disease	0,73	neutral	0,19	6	deleterious	1	neutral	0,13	deleterious	3	deleterious	0,47	NA	NA	NA	NA	NA	NA	0,38	0,85	20,59	8,49	N	0,36	N	0,81	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5280	5280	A	T	MI.14460	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	811	271	T	S	Aca/Tca	-3,34	0	0	possibly_damaging	0,56	neutral	0,44	neutral	4,15	neutral	-0,88	deleterious	-3,44	medium_impact	2,15	neutral	0,87	neutral	0,66	neutral	1,39	12,76	0,34	0,5	disease	0,68	disease	0,51	neutral	0,26	neutral	0,23	5	neutral	0,59	neutral	0,44	NA	0	deleterious	0,54	medium_impact	-0,89	medium_impact	0,15	medium_impact	0,67	0,53	0,8	0,58	8,4	N	0,36	N	0,32	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5280	5280	A	G	MI.14461	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	811	271	T	A	Aca/Gca	-3,34	0	0	benign	0,04	neutral	0,53	neutral	4,2	neutral	0,37	deleterious	-4,12	medium_impact	2,22	neutral	0,87	neutral	0,77	deleterious	0,46	7,16	0,26	0,45	disease	0,61	neutral	0,39	neutral	0,28	disease	0,59	2	neutral	0,43	deleterious	0,75	neutral	-3	neutral	0,2	medium_impact	0,47	medium_impact	0,24	medium_impact	0,72	0,28	0,8	0,58	8,4	N	0,32	N	0,08	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5280	5280	A	C	MI.14462	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	811	271	T	P	Aca/Cca	-3,34	0	0	probably_damaging	0,9	neutral	0,18	neutral	4,1	neutral	-2,45	deleterious	-5,23	high_impact	3,96	neutral	0,77	neutral	0,33	deleterious	1,94	15,82	0,04	0,35	disease	0,87	disease	0,8	disease	0,7	disease	0,66	3	neutral	0,94	neutral	0,14	deleterious	2	deleterious	0,76	low_impact	-1,67	medium_impact	-0,16	high_impact	2,19	0,24	0,8	0,58	8,4	N	0,34	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5281	5281	C	A	MI.14463	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	812	271	T	K	aCa/aAa	1,98	0	0	possibly_damaging	0,76	neutral	0,41	neutral	4,1	neutral	-2,19	deleterious	-5,21	medium_impact	3,4	neutral	0,88	neutral	0,37	deleterious	2,72	20,9	0,05	0,35	disease	0,83	disease	0,8	disease	0,67	disease	0,65	3	neutral	0,76	neutral	0,33	NA	0	deleterious	0,73	low_impact	-1,26	medium_impact	0,12	medium_impact	1,72	0,32	0,8	0,58	8,4	N	0,37	N	0,65	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5281	5281	C	T	MI.14464	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	812	271	T	M	aCa/aTa	1,98	0	0	probably_damaging	0,97	neutral	0,25	neutral	4,16	neutral	-0,75	deleterious	-4,8	medium_impact	2,03	neutral	0,88	neutral	0,83	deleterious	2,75	21,1	0,1	0,4	neutral	0,41	disease	0,62	neutral	0,42	neutral	0,34	3	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,67	low_impact	-2,18	medium_impact	-0,06	medium_impact	0,56	0,46	0,8	0,58	8,4	N	0,41	N	0,24	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5283	5283	A	G	MI.14465	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	814	272	K	E	Aaa/Gaa	-4,5	0	0	possibly_damaging	0,7	neutral	0,31	neutral	4,25	neutral	0,56	deleterious	-3,42	low_impact	1,78	neutral	0,93	neutral	0,65	deleterious	4,05	23,7	0,26	0,45	disease	0,6	disease	0,86	disease	0,58	disease	0,64	3	neutral	0,76	neutral	0,31	neutral	-3	deleterious	0,66	low_impact	-1,13	medium_impact	0,02	medium_impact	0,35	0,56	0,8	NA	NA	N	0,39	N	0,73	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5283	5283	A	C	MI.14466	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	814	272	K	Q	Aaa/Caa	-4,5	0	0	possibly_damaging	0,84	neutral	0,36	neutral	4,22	neutral	0,08	deleterious	-3,38	medium_impact	2,36	neutral	0,86	neutral	0,51	deleterious	3,48	23,1	0,43	0,55	disease	0,68	disease	0,76	disease	0,54	disease	0,6	2	neutral	0,86	neutral	0,26	NA	0	deleterious	0,7	low_impact	-1,46	medium_impact	0,07	medium_impact	0,84	0,4	0,8	NA	NA	N	0,31	N	0,66	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5284	5284	A	C	MI.14467	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	815	272	K	T	aAa/aCa	2,9	0,98	0	possibly_damaging	0,8	neutral	0,43	neutral	4,16	neutral	-1	deleterious	-5,02	low_impact	1,43	neutral	0,9	neutral	0,66	deleterious	2,36	18,55	0,13	0,4	neutral	0,42	disease	0,7	neutral	0,31	neutral	0,17	7	neutral	0,79	neutral	0,32	neutral	-3	deleterious	0,61	low_impact	-1,35	medium_impact	0,14	medium_impact	0,06	0,33	0,8	NA	NA	N	0,51	P	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5284	5284	A	T	MI.14468	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	815	272	K	M	aAa/aTa	2,9	0,98	0	benign	0,21	neutral	0,29	neutral	4,1	deleterious	-3,07	deleterious	-5,05	medium_impact	2,06	neutral	0,88	neutral	0,71	deleterious	3,69	23,3	0,14	0,4	disease	0,88	disease	0,72	neutral	0,43	neutral	0,43	1	neutral	0,65	deleterious	0,54	neutral	-3	neutral	0,38	medium_impact	-0,27	medium_impact	-0,01	medium_impact	0,59	0,26	0,8	NA	NA	N	0,5	N	0,41	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5285	5285	A	C	MI.14469	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	816	272	K	N	aaA/aaC	2,21	0,99	0	benign	0,09	neutral	0,33	neutral	4,16	neutral	-0,61	deleterious	-4,05	low_impact	1,66	neutral	0,91	neutral	0,82	deleterious	3,61	23,2	0,57	0,65	neutral	0,45	disease	0,69	neutral	0,3	neutral	0,17	7	neutral	0,63	deleterious	0,62	neutral	-6	neutral	0,24	medium_impact	0,12	medium_impact	0,04	medium_impact	0,25	0,36	0,8	NA	NA	P	0,55	P	0,64	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8367	8367	T	A	MI.1447	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	2	1	M	K	aTg/aAg	8,46	1	0	possibly_damaging	0,88	deleterious	0	deleterious	-2,13	deleterious	-13,27	deleterious	-5,96	NA	NA	neutral	0,87	damaging	0,06	deleterious	3,83	23,4	0,18003069	0,85	disease	0,78	neutral	0,21	disease	0,75	neutral	0,26	5	deleterious	1	neutral	0,06	deleterious	3	deleterious	0,73	NA	NA	NA	NA	NA	NA	0,33	0,85	20,59	8,49	P	0,59	P	0,93	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5285	5285	A	T	MI.14470	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	816	272	K	N	aaA/aaT	2,21	0,99	0	benign	0,09	neutral	0,33	neutral	4,16	neutral	-0,61	deleterious	-4,05	low_impact	1,66	neutral	0,91	neutral	0,82	deleterious	3,69	23,3	0,57	0,65	neutral	0,45	disease	0,69	neutral	0,3	neutral	0,17	7	neutral	0,63	deleterious	0,62	neutral	-6	neutral	0,24	medium_impact	0,12	medium_impact	0,04	medium_impact	0,25	0,36	0,8	NA	NA	P	0,56	P	0,64	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5286	5286	A	T	MI.14471	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	817	273	N	Y	Aac/Tac	0,82	0,99	0	probably_damaging	1	neutral	1	neutral	4,12	neutral	-2	deleterious	-7,62	medium_impact	2,46	neutral	0,89	neutral	0,3	deleterious	3,48	23,1	0,23	0,45	disease	0,9	disease	0,8	neutral	0,4	disease	0,61	2	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,85	low_impact	-3,54	high_impact	1,87	medium_impact	0,93	0,2	0,8	NA	NA	N	0,34	N	0,64	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5286	5286	A	C	MI.14472	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	817	273	N	H	Aac/Cac	0,82	0,99	0	probably_damaging	1	neutral	0,53	neutral	4,14	neutral	-1,06	deleterious	-4,77	medium_impact	1,95	neutral	0,86	neutral	0,35	deleterious	1,93	15,79	0,54	0,6	disease	0,87	disease	0,61	neutral	0,36	disease	0,5	0	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,24	medium_impact	0,5	0,15	0,8	NA	NA	N	0,35	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5286	5286	A	G	MI.14473	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	817	273	N	D	Aac/Gac	0,82	0,99	0	probably_damaging	1	neutral	0,24	neutral	4,16	neutral	-0,5	deleterious	-4,76	medium_impact	2,89	neutral	0,89	damaging	0,11	deleterious	3,72	23,3	0,73	0,75	disease	0,8	disease	0,71	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	-0,07	medium_impact	1,29	0,39	0,8	NA	NA	N	0,5	N	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5287	5287	A	C	MI.14474	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	818	273	N	T	aAc/aCc	2,21	1	0	probably_damaging	1	neutral	0,42	neutral	4,17	neutral	-0,39	deleterious	-5,71	medium_impact	2,25	neutral	0,84	damaging	0,18	deleterious	3,36	22,9	0,4	0,5	disease	0,56	disease	0,66	disease	0,61	disease	0,6	2	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,13	medium_impact	0,75	0,24	0,8	NA	NA	N	0,4	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5287	5287	A	G	MI.14475	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	818	273	N	S	aAc/aGc	2,21	1	0	probably_damaging	1	neutral	0,53	neutral	4,27	neutral	0,56	deleterious	-4,75	low_impact	1,51	neutral	0,87	damaging	0,23	deleterious	2,99	22,2	0,64	0,7	neutral	0,44	disease	0,65	disease	0,62	disease	0,6	2	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,75	low_impact	-3,54	medium_impact	0,24	medium_impact	0,13	0,25	0,8	NA	NA	N	0,38	N	0,74	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5287	5287	A	T	MI.14476	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	818	273	N	I	aAc/aTc	2,21	1	0	probably_damaging	1	neutral	0,48	neutral	4,12	neutral	-2,22	deleterious	-8,56	medium_impact	2,73	neutral	0,87	damaging	0,11	deleterious	3,84	23,4	0,22	0,45	disease	0,67	disease	0,87	disease	0,59	disease	0,72	4	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	0,19	medium_impact	1,15	0,16	0,8	NA	NA	N	0,42	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5288	5288	C	A	MI.14477	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	819	273	N	K	aaC/aaA	6,6	1	0	probably_damaging	1	neutral	0,33	neutral	4,19	neutral	-0,13	deleterious	-5,71	medium_impact	2,34	neutral	0,91	damaging	0,1	deleterious	4,45	24,2	0,6	0,65	disease	0,71	disease	0,8	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,04	medium_impact	0,83	0,42	0,8	NA	NA	P	0,55	P	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5288	5288	C	G	MI.14478	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	819	273	N	K	aaC/aaG	6,6	1	0	probably_damaging	1	neutral	0,33	neutral	4,19	neutral	-0,13	deleterious	-5,71	medium_impact	2,34	neutral	0,91	damaging	0,1	deleterious	3,99	23,6	0,6	0,65	disease	0,71	disease	0,8	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,04	medium_impact	0,83	0,42	0,8	NA	NA	P	0,55	P	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5289	5289	A	T	MI.14479	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	820	274	N	Y	Aat/Tat	-0,8	0	0	possibly_damaging	0,89	neutral	1	neutral	4,08	neutral	-2,61	deleterious	-5,48	medium_impact	2,84	neutral	0,9	neutral	0,75	deleterious	1,87	15,4	0,13	0,4	disease	0,71	disease	0,81	disease	0,59	disease	0,62	2	neutral	0,89	deleterious	0,56	NA	0	deleterious	0,73	low_impact	-1,63	high_impact	1,87	medium_impact	1,25	0,2	0,8	1,15	8,25	N	0,25	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8367	8367	T	C	MI.1448	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	2	1	M	T	aTg/aCg	8,46	1	0	possibly_damaging	0,88	deleterious	0	deleterious	-2,12	deleterious	-12,66	deleterious	-5,96	NA	NA	neutral	0,88	damaging	0,09	deleterious	2,67	20,6	0,34561211	0,85	disease	0,73	neutral	0,2	disease	0,73	neutral	0,26	5	deleterious	1	neutral	0,06	deleterious	3	deleterious	0,71	NA	NA	NA	NA	NA	NA	0,24	0,85	20,59	8,49	P	0,58	P	0,88	NA	NA	0,5	.	.	.	.	.	MNGIE fibroblasts	.	.	.	.	.	.	.	.	.
chrM	5289	5289	A	C	MI.14480	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	820	274	N	H	Aat/Cat	-0,8	0	0	probably_damaging	0,92	neutral	0,53	neutral	4,12	neutral	-1,57	deleterious	-3,08	medium_impact	2,63	neutral	0,82	neutral	0,94	deleterious	0,34	6,05	0,49	0,55	disease	0,82	disease	0,61	neutral	0,44	neutral	0,35	3	neutral	0,92	neutral	0,31	deleterious	1	deleterious	0,71	low_impact	-1,77	medium_impact	0,24	medium_impact	1,07	0,21	0,8	1,15	8,25	N	0,28	N	0,54	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5289	5289	A	G	MI.14481	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	820	274	N	D	Aat/Gat	-0,8	0	0	benign	0,02	neutral	0,23	neutral	4,14	neutral	-0,96	neutral	-1,75	low_impact	0,92	neutral	0,87	neutral	0,99	deleterious	0,25	5,21	0,77	0,8	disease	0,71	neutral	0,35	neutral	0,41	disease	0,64	3	neutral	0,76	deleterious	0,61	neutral	-6	neutral	0,2	medium_impact	0,75	medium_impact	-0,08	medium_impact	-0,37	0,34	0,8	1,15	8,25	N	0,47	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5290	5290	A	G	MI.14482	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	821	274	N	S	aAt/aGt	-0,8	0	0	benign	0,04	neutral	0,42	neutral	4,16	neutral	-0,72	deleterious	-2,7	low_impact	1,51	neutral	0,83	neutral	0,98	deleterious	0,19	4,59	0,6	0,65	neutral	0,43	disease	0,61	neutral	0,41	neutral	0,2	6	neutral	0,54	deleterious	0,69	neutral	-6	neutral	0,21	medium_impact	0,47	medium_impact	0,13	medium_impact	0,13	0,28	0,8	1,15	8,25	N	0,36	N	0,56	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5290	5290	A	C	MI.14483	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	821	274	N	T	aAt/aCt	-0,8	0	0	benign	0,36	neutral	0,4	neutral	4,13	neutral	-1,06	deleterious	-3,84	medium_impact	2,84	neutral	0,91	neutral	0,61	neutral	1,6	13,86	0,39	0,5	neutral	0,44	disease	0,69	disease	0,63	disease	0,68	4	neutral	0,53	deleterious	0,52	neutral	-3	neutral	0,38	medium_impact	-0,57	medium_impact	0,11	medium_impact	1,25	0,23	0,8	1,15	8,25	N	0,36	N	0,6	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5290	5290	A	T	MI.14484	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	821	274	N	I	aAt/aTt	-0,8	0	0	possibly_damaging	0,85	neutral	0,42	neutral	4,07	neutral	-2,99	deleterious	-6,31	medium_impact	3,29	neutral	0,9	neutral	0,47	deleterious	2,39	18,76	0,13	0,4	neutral	0,49	disease	0,86	disease	0,61	disease	0,73	5	neutral	0,85	neutral	0,29	NA	0	deleterious	0,66	low_impact	-1,49	medium_impact	0,13	medium_impact	1,63	0,17	0,8	1,15	8,25	N	0,39	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5291	5291	T	A	MI.14485	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	822	274	N	K	aaT/aaA	0,82	0	0	benign	0,36	neutral	0,29	neutral	4,16	neutral	-0,63	deleterious	-3,69	medium_impact	2,23	neutral	0,89	neutral	0,69	deleterious	2,58	19,99	0,51	0,6	disease	0,76	disease	0,81	disease	0,65	disease	0,61	2	neutral	0,66	neutral	0,47	neutral	-3	deleterious	0,53	medium_impact	-0,57	medium_impact	-0,01	medium_impact	0,73	0,4	0,8	1,15	8,25	N	0,42	N	0,47	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5291	5291	T	G	MI.14486	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	822	274	N	K	aaT/aaG	0,82	0	0	benign	0,36	neutral	0,29	neutral	4,16	neutral	-0,63	deleterious	-3,69	medium_impact	2,23	neutral	0,89	neutral	0,69	deleterious	2,2	17,52	0,51	0,6	disease	0,76	disease	0,81	disease	0,65	disease	0,61	2	neutral	0,66	neutral	0,47	neutral	-3	deleterious	0,53	medium_impact	-0,57	medium_impact	-0,01	medium_impact	0,73	0,4	0,8	1,15	8,25	N	0,4	N	0,47	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5292	5292	A	C	MI.14487	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	823	275	S	R	Agc/Cgc	-5,89	0	0	benign	0,26	neutral	0,15	neutral	4,15	neutral	-1,16	neutral	-2,31	medium_impact	2,23	neutral	0,86	neutral	0,44	deleterious	0,6	8,16	0,11	0,4	disease	0,76	disease	0,63	disease	0,62	disease	0,72	4	neutral	0,82	neutral	0,45	neutral	-3	neutral	0,3	medium_impact	-0,38	medium_impact	-0,21	medium_impact	0,73	0,55	0,8	0,58	7,49	N	0,31	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5292	5292	A	T	MI.14488	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	823	275	S	C	Agc/Tgc	-5,89	0	0	possibly_damaging	0,76	neutral	0,12	neutral	4,11	deleterious	-3,87	deleterious	-3,15	medium_impact	2,44	neutral	0,94	neutral	0,91	deleterious	0,34	6,03	0,14	0,4	neutral	0,42	neutral	0,46	neutral	0,32	disease	0,5	0	neutral	0,91	neutral	0,18	NA	0	deleterious	0,45	low_impact	-1,26	medium_impact	-0,27	medium_impact	0,91	0,28	0,8	0,58	7,49	N	0,52	P	0,29	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5292	5292	A	G	MI.14489	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	823	275	S	G	Agc/Ggc	-5,89	0	0	benign	0,08	neutral	0,25	neutral	4,17	neutral	-0,66	neutral	-2,33	low_impact	1,74	neutral	0,93	neutral	0,83	deleterious	0,3	5,71	0,26	0,45	disease	0,54	neutral	0,29	neutral	0,44	neutral	0,49	0	neutral	0,72	deleterious	0,59	neutral	-6	neutral	0,15	medium_impact	0,17	medium_impact	-0,06	medium_impact	0,32	0,57	0,8	0,58	7,49	N	0,43	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8368	8368	G	T	MI.1449	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	3	1	M	I	atG/atT	7,53	1	0	possibly_damaging	0,82	deleterious	0	deleterious	-2,12	deleterious	-11,44	deleterious	-3,97	NA	NA	neutral	0,89	damaging	0,06	deleterious	3,27	22,8	0,29054267	0,85	disease	0,52	neutral	0,1	disease	0,73	neutral	0,19	6	deleterious	1	neutral	0,09	deleterious	3	deleterious	0,57	NA	NA	NA	NA	NA	NA	0,56	0,85	20,59	8,49	P	0,6	P	0,71	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5293	5293	G	A	MI.14490	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	824	275	S	N	aGc/aAc	0,13	0	0	benign	0	neutral	0,21	neutral	4,17	neutral	-1,17	neutral	0,13	neutral_impact	-0,38	neutral	0,93	neutral	0,94	neutral	-0,95	0,02	0,61	0,65	disease	0,78	neutral	0,2	neutral	0,24	disease	0,53	1	neutral	0,79	deleterious	0,61	neutral	-6	neutral	0,19	medium_impact	1,95	medium_impact	-0,11	low_impact	-1,46	0,34	0,8	0,58	7,49	N	0,46	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5293	5293	G	C	MI.14491	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	824	275	S	T	aGc/aCc	0,13	0	0	benign	0	neutral	0,32	neutral	4,18	neutral	-0,7	neutral	-1,38	low_impact	1,2	neutral	0,95	neutral	0,78	deleterious	0,19	4,55	0,33	0,5	neutral	0,5	neutral	0,21	neutral	0,28	neutral	0,27	5	neutral	0,68	deleterious	0,66	neutral	-6	neutral	0,14	medium_impact	1,95	medium_impact	0,03	medium_impact	-0,13	0,58	0,8	0,58	7,49	N	0,47	N	0,16	polymorphism	1	0,02	rs28690990	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5293	5293	G	T	MI.14492	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	824	275	S	I	aGc/aTc	0,13	0	0	benign	0,2	neutral	0,38	neutral	4,14	neutral	-1,58	deleterious	-2,97	low_impact	1,36	neutral	0,88	neutral	0,68	neutral	1,02	10,78	0,12	0,4	neutral	0,41	disease	0,54	neutral	0,34	neutral	0,49	0	neutral	0,54	deleterious	0,59	neutral	-6	neutral	0,22	medium_impact	-0,25	medium_impact	0,09	medium_impact	0	0,3	0,8	0,58	7,49	N	0,36	N	0,67	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5295	5295	C	A	MI.14493	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	826	276	L	I	Ctc/Atc	-1,96	0	0	benign	0,06	neutral	0,69	neutral	4,13	neutral	-1,09	neutral	1,23	neutral_impact	-1	neutral	0,87	neutral	0,89	neutral	1,4	12,8	0,4	0,5	neutral	0,46	neutral	0,05	neutral	0,16	neutral	0,22	6	neutral	0,22	deleterious	0,82	neutral	-6	neutral	0,14	medium_impact	0,3	medium_impact	0,4	low_impact	-1,99	0,52	0,8	1,73	8,64	N	0,41	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5295	5295	C	G	MI.14494	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	826	276	L	V	Ctc/Gtc	-1,96	0	0	benign	0,23	neutral	0,59	neutral	4,12	neutral	-0,9	neutral	0,52	neutral_impact	0,46	neutral	0,89	neutral	0,93	deleterious	2,28	18	0,37	0,5	disease	0,55	neutral	0,18	neutral	0,38	neutral	0,38	3	neutral	0,3	deleterious	0,68	neutral	-6	neutral	0,31	medium_impact	-0,32	medium_impact	0,3	medium_impact	-0,76	0,61	0,8	1,73	8,64	N	0,37	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5295	5295	C	T	MI.14495	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	826	276	L	F	Ctc/Ttc	-1,96	0	0	benign	0,02	neutral	0,77	neutral	4,06	neutral	-1,88	neutral	-1,56	neutral_impact	0,72	neutral	0,97	neutral	0,85	deleterious	2,94	22	0,26	0,45	disease	0,72	neutral	0,27	neutral	0,4	disease	0,57	1	neutral	0,18	deleterious	0,88	neutral	-6	neutral	0,2	medium_impact	0,75	medium_impact	0,5	medium_impact	-0,54	0,64	0,8	1,73	8,64	N	0,27	N	0,1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5296	5296	T	A	MI.14496	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	827	276	L	H	cTc/cAc	-1,49	0	0	possibly_damaging	0,87	neutral	0,46	neutral	3,99	deleterious	-4,09	deleterious	-4,48	low_impact	1,58	neutral	0,86	neutral	0,64	deleterious	4,18	23,8	0,05	0,35	disease	0,85	neutral	0,35	disease	0,53	disease	0,65	3	neutral	0,86	neutral	0,3	neutral	-3	deleterious	0,67	low_impact	-1,55	medium_impact	0,17	medium_impact	0,19	0,18	0,8	1,73	8,64	N	0,35	N	0,71	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5296	5296	T	G	MI.14497	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	827	276	L	R	cTc/cGc	-1,49	0	0	possibly_damaging	0,89	neutral	0,3	neutral	3,99	deleterious	-3,82	deleterious	-4,47	medium_impact	2,62	neutral	0,84	neutral	0,44	deleterious	4,27	23,9	0,02	0,35	disease	0,8	disease	0,62	disease	0,58	disease	0,72	4	neutral	0,91	neutral	0,21	NA	0	deleterious	0,75	low_impact	-1,63	medium_impact	0	medium_impact	1,06	0,17	0,8	1,73	8,64	N	0,33	N	0,74	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5296	5296	T	C	MI.14498	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	827	276	L	P	cTc/cCc	-1,49	0	0	probably_damaging	0,93	neutral	0,39	neutral	4,02	neutral	-2,97	deleterious	-4,48	neutral_impact	-0,08	neutral	0,85	neutral	0,86	deleterious	2,69	20,8	0,03	0,35	neutral	0,42	neutral	0,43	neutral	0,43	neutral	0,46	1	neutral	0,93	neutral	0,23	neutral	-2	deleterious	0,69	low_impact	-1,83	medium_impact	0,1	low_impact	-1,21	0,11	0,8	1,73	8,64	N	0,31	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5298	5298	A	G	MI.14499	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	829	277	I	V	Atc/Gtc	-11,21	0	0	benign	0,01	neutral	0,46	neutral	4,26	neutral	0,54	neutral	-0,62	low_impact	1,3	neutral	0,98	neutral	0,95	deleterious	0,09	3,46	0,6	0,65	disease	0,56	neutral	0,16	neutral	0,36	neutral	0,39	2	neutral	0,53	deleterious	0,73	neutral	-6	neutral	0,14	medium_impact	1,03	medium_impact	0,17	medium_impact	-0,05	0,4	0,8	4,32	7,56	N	0,37	N	0,62	polymorphism	1	0,02	.	.	.	.	.	papillary thyroid carcinoma	.	.	.	.	.	.	.	.	.
chrM	8594	8594	T	A	MI.145	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	68	23	I	N	aTc/aAc	2,67	0,98	0	probably_damaging	0,91	neutral	0,12	neutral	4,26	neutral	-2,82	deleterious	-4,03	low_impact	1,36	neutral	0,87	neutral	0,37	deleterious	4,16	23,8	0,3	0,65	disease	0,86	disease	0,73	disease	0,55	disease	0,75	5	neutral	0,96	neutral	0,11	neutral	-2	deleterious	0,78	low_impact	-1,71	medium_impact	-0,2	medium_impact	0,07	0,6	0,9	19,03	10,37	N	0,46	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8368	8368	G	C	MI.1450	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	3	1	M	I	atG/atC	7,53	1	0	possibly_damaging	0,82	deleterious	0	deleterious	-2,12	deleterious	-11,44	deleterious	-3,97	NA	NA	neutral	0,89	damaging	0,06	deleterious	3,14	22,6	0,29054267	0,85	disease	0,52	neutral	0,1	disease	0,73	neutral	0,19	6	deleterious	1	neutral	0,09	deleterious	3	deleterious	0,57	NA	NA	NA	NA	NA	NA	0,56	0,85	20,59	8,49	P	0,6	P	0,71	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5298	5298	A	C	MI.14500	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	829	277	I	L	Atc/Ctc	-11,21	0	0	benign	0,01	neutral	1	neutral	4,31	neutral	0,61	neutral	-1,17	low_impact	1,1	neutral	0,94	neutral	0,95	deleterious	0,64	8,45	0,22	0,45	disease	0,51	neutral	0,19	neutral	0,25	neutral	0,27	5	neutral	0,01	deleterious	1	neutral	-6	neutral	0,13	medium_impact	1,03	high_impact	1,87	medium_impact	-0,22	0,63	0,8	4,32	7,56	N	0,3	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5298	5298	A	T	MI.14501	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	829	277	I	F	Atc/Ttc	-11,21	0	0	possibly_damaging	0,52	neutral	0,66	neutral	4,21	neutral	-0,53	deleterious	-3,07	low_impact	0,96	neutral	0,89	neutral	0,81	neutral	1,09	11,18	0,21	0,45	disease	0,62	neutral	0,46	neutral	0,34	disease	0,57	1	neutral	0,44	deleterious	0,57	neutral	-3	deleterious	0,52	medium_impact	-0,83	medium_impact	0,37	medium_impact	-0,34	0,56	0,8	4,32	7,56	N	0,31	N	0,61	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5299	5299	T	A	MI.14502	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	830	277	I	N	aTc/aAc	-1,96	0	0	possibly_damaging	0,75	neutral	0,14	neutral	4,09	deleterious	-3,13	deleterious	-5,44	high_impact	3,59	neutral	0,87	neutral	0,41	deleterious	4,23	23,9	0,09	0,4	disease	0,83	disease	0,58	disease	0,63	disease	0,67	3	neutral	0,9	neutral	0,2	deleterious	1	deleterious	0,63	low_impact	-1,23	medium_impact	-0,23	medium_impact	1,88	0,24	0,8	4,32	7,56	N	0,43	N	0,88	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5299	5299	T	G	MI.14503	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	830	277	I	S	aTc/aGc	-1,96	0	0	benign	0,29	neutral	0,45	neutral	4,12	neutral	-1,69	deleterious	-4,45	medium_impact	2,12	neutral	0,81	neutral	0,82	deleterious	2,57	19,91	0,04	0,35	disease	0,55	disease	0,53	neutral	0,42	neutral	0,27	5	neutral	0,46	deleterious	0,58	neutral	-3	neutral	0,38	medium_impact	-0,44	medium_impact	0,16	medium_impact	0,64	0,24	0,8	4,32	7,56	N	0,32	N	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5299	5299	T	C	MI.14504	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	830	277	I	T	aTc/aCc	-1,96	0	0	benign	0,03	neutral	0,55	neutral	4,15	neutral	-0,9	deleterious	-3,46	low_impact	1,36	neutral	0,9	neutral	0,97	deleterious	0,41	6,68	0,14	0,4	disease	0,69	neutral	0,22	neutral	0,39	neutral	0,5	0	neutral	0,41	deleterious	0,76	neutral	-6	neutral	0,19	medium_impact	0,59	medium_impact	0,26	medium_impact	0	0,24	0,8	4,32	7,56	N	0,37	N	0,47	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5300	5300	C	G	MI.14505	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	831	277	I	M	atC/atG	-0,34	0	0,01	possibly_damaging	0,68	neutral	0,59	neutral	4,12	neutral	-1,77	neutral	-1,54	low_impact	1,08	neutral	0,84	neutral	0,95	deleterious	0,54	7,76	0,35	0,5	disease	0,6	neutral	0,2	neutral	0,31	neutral	0,46	1	neutral	0,63	neutral	0,46	neutral	-3	deleterious	0,51	low_impact	-1,1	medium_impact	0,3	medium_impact	-0,24	0,64	0,8	4,32	7,56	N	0,32	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5300	5300	C	A	MI.14506	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	831	277	I	M	atC/atA	-0,34	0	0,01	possibly_damaging	0,68	neutral	0,59	neutral	4,12	neutral	-1,77	neutral	-1,54	low_impact	1,08	neutral	0,84	neutral	0,95	neutral	1,07	11,04	0,35	0,5	disease	0,6	neutral	0,2	neutral	0,31	neutral	0,46	1	neutral	0,63	neutral	0,46	neutral	-3	deleterious	0,51	low_impact	-1,1	medium_impact	0,3	medium_impact	-0,24	0,64	0,8	4,32	7,56	N	0,32	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5301	5301	A	G	MI.14507	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	832	278	I	V	Atc/Gtc	-10,98	0	0,08	benign	0,04	neutral	0,75	neutral	4,23	neutral	0,19	neutral	-0,51	neutral_impact	0,62	neutral	0,96	neutral	0,9	deleterious	0,03	2,86	0,55	0,6	neutral	0,46	neutral	0,11	neutral	0,32	neutral	0,33	3	neutral	0,19	deleterious	0,86	neutral	-6	neutral	0,1	medium_impact	0,47	medium_impact	0,47	medium_impact	-0,62	0,39	0,8	NA	NA	N	0,29	N	0,47	polymorphism	1	0,02	rs199794187	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5301	5301	A	C	MI.14508	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	832	278	I	L	Atc/Ctc	-10,98	0	0,08	benign	0	neutral	1	neutral	4,54	neutral	1,71	neutral	0,93	neutral_impact	-1,36	neutral	0,87	neutral	0,94	neutral	-0,74	0,06	0,25	0,45	neutral	0,38	neutral	0,14	neutral	0,23	neutral	0,24	5	neutral	0	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,95	high_impact	1,87	low_impact	-2,29	0,68	0,85	NA	NA	N	0,38	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5301	5301	A	T	MI.14509	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	832	278	I	F	Atc/Ttc	-10,98	0	0,08	benign	0	neutral	0,81	neutral	4,13	neutral	-1,35	neutral	-1,64	neutral_impact	0,7	neutral	0,89	neutral	0,81	deleterious	1,86	15,35	0,19	0,45	neutral	0,43	neutral	0,41	neutral	0,38	neutral	0,44	1	neutral	0,17	deleterious	0,91	neutral	-6	neutral	0,14	medium_impact	1,95	medium_impact	0,56	medium_impact	-0,56	0,52	0,8	NA	NA	N	0,33	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8369	8369	C	T	MI.1451	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	4	2	P	S	Ccc/Tcc	5,22	1	0	probably_damaging	1	deleterious	0,02	neutral	-1,21	deleterious	-9,22	deleterious	-7,95	high_impact	3,9	neutral	0,99	neutral	0,45	deleterious	3,64	23,2	0,46398601	0,85	disease	0,79	neutral	0,1	disease	0,52	neutral	0,21	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,6	medium_impact	-0,66	high_impact	2,25	0,17	0,85	22,06	7,2	P	0,65	P	0,94	disease_causing	0,98	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5302	5302	T	A	MI.14510	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	833	278	I	N	aTc/aAc	-6,58	0	0	benign	0,14	neutral	0,24	neutral	4,07	deleterious	-3,39	deleterious	-4,2	low_impact	1,86	neutral	0,89	neutral	0,45	deleterious	2,61	20,3	0,09	0,35	disease	0,69	disease	0,51	disease	0,63	disease	0,68	4	neutral	0,72	deleterious	0,55	neutral	-6	neutral	0,26	medium_impact	-0,08	medium_impact	-0,07	medium_impact	0,42	0,28	0,8	NA	NA	N	0,39	N	0,77	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5302	5302	T	G	MI.14511	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	833	278	I	S	aTc/aGc	-6,58	0	0	benign	0,06	neutral	0,68	neutral	4,1	neutral	-1,92	deleterious	-3,23	low_impact	1,17	neutral	0,88	neutral	0,74	deleterious	2,38	18,7	0,03	0,35	disease	0,61	neutral	0,46	disease	0,6	disease	0,6	2	neutral	0,24	deleterious	0,81	neutral	-6	neutral	0,17	medium_impact	0,3	medium_impact	0,39	medium_impact	-0,16	0,27	0,8	NA	NA	N	0,26	N	0,4	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5302	5302	T	C	MI.14512	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	833	278	I	T	aTc/aCc	-6,58	0	0	benign	0	neutral	0,75	neutral	4,14	neutral	-1,53	deleterious	-2,5	neutral_impact	-0,18	neutral	0,99	neutral	0,96	deleterious	0,01	2,64	0,12	0,4	disease	0,63	neutral	0,1	neutral	0,31	neutral	0,33	3	neutral	0,24	deleterious	0,88	neutral	-6	neutral	0,09	medium_impact	1,95	medium_impact	0,47	low_impact	-1,3	0,35	0,8	NA	NA	N	0,33	N	0,06	polymorphism	1	0,07	rs878853115	Benign	not_provided	RCV000224519.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	5303	5303	C	G	MI.14513	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	834	278	I	M	atC/atG	0,36	0	0	benign	0,01	neutral	0,55	neutral	4,11	neutral	-1,75	neutral	0,83	neutral_impact	-0,82	neutral	0,96	neutral	0,92	neutral	-0,67	0,09	0,33	0,5	neutral	0,5	neutral	0,1	neutral	0,25	neutral	0,21	6	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	0,26	low_impact	-1,84	0,7	0,85	NA	NA	N	0,35	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5303	5303	C	A	MI.14514	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	834	278	I	M	atC/atA	0,36	0	0	benign	0,01	neutral	0,55	neutral	4,11	neutral	-1,75	neutral	0,83	neutral_impact	-0,82	neutral	0,96	neutral	0,92	neutral	-0,23	0,96	0,33	0,5	neutral	0,5	neutral	0,1	neutral	0,25	neutral	0,21	6	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	0,26	low_impact	-1,84	0,7	0,85	NA	NA	N	0,37	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5304	5304	C	T	MI.14515	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	835	279	P	S	Ccc/Tcc	-2,19	0	0	probably_damaging	1	neutral	0,5	neutral	4,25	neutral	-0,65	deleterious	-5,87	neutral_impact	-0,12	neutral	0,84	neutral	0,92	deleterious	2,71	20,9	0,22	0,45	neutral	0,39	neutral	0,38	neutral	0,33	neutral	0,43	2	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,7	low_impact	-3,54	medium_impact	0,21	low_impact	-1,25	0,24	0,8	NA	NA	N	0,28	N	0,27	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5304	5304	C	G	MI.14516	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	835	279	P	A	Ccc/Gcc	-2,19	0	0	probably_damaging	1	neutral	0,72	neutral	4,55	neutral	1,85	deleterious	-5,9	neutral_impact	-0,85	neutral	0,9	neutral	0,89	neutral	0,9	10,09	0,18	0,45	neutral	0,38	neutral	0,07	neutral	0,3	neutral	0,18	7	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,67	low_impact	-3,54	medium_impact	0,44	low_impact	-1,86	0,75	0,85	NA	NA	N	0,38	N	0,42	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5304	5304	C	A	MI.14517	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	835	279	P	T	Ccc/Acc	-2,19	0	0	probably_damaging	1	neutral	0,58	neutral	4,25	neutral	-0,33	deleterious	-6,17	neutral_impact	0,72	neutral	0,9	neutral	0,47	deleterious	3,68	23,3	0,18	0,45	disease	0,55	neutral	0,35	neutral	0,46	disease	0,58	2	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	0,29	medium_impact	-0,54	0,66	0,8	NA	NA	N	0,32	N	0,6	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5305	5305	C	T	MI.14518	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	836	279	P	L	cCc/cTc	0,82	0,28	0	probably_damaging	1	neutral	0,75	neutral	4,33	neutral	0,61	deleterious	-8,09	neutral_impact	0,57	neutral	0,86	damaging	0,12	deleterious	4,5	24,3	0,12	0,4	neutral	0,5	disease	0,6	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,38	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	0,47	medium_impact	-0,67	0,7	0,85	NA	NA	N	0,23	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5305	5305	C	A	MI.14519	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	836	279	P	H	cCc/cAc	0,82	0,28	0	probably_damaging	1	neutral	0,52	neutral	4,17	neutral	-2,92	deleterious	-7,29	medium_impact	2,89	neutral	0,88	damaging	0,11	deleterious	4,13	23,8	0,1	0,4	disease	0,59	disease	0,52	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,23	medium_impact	1,29	0,41	0,8	NA	NA	N	0,31	N	0,88	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8369	8369	C	A	MI.1452	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	4	2	P	T	Ccc/Acc	5,22	1	0	probably_damaging	1	deleterious	0	neutral	-1,19	deleterious	-8,28	deleterious	-7,95	high_impact	3,9	neutral	0,99	neutral	0,46	deleterious	3,43	23	0,36427644	0,85	disease	0,83	neutral	0,12	disease	0,53	neutral	0,22	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,6	low_impact	-1,4	high_impact	2,25	0,35	0,85	22,06	7,2	P	0,65	P	0,92	disease_causing	0,98	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5305	5305	C	G	MI.14520	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	836	279	P	R	cCc/cGc	0,82	0,28	0	probably_damaging	1	neutral	0,34	neutral	4,18	neutral	-2,31	deleterious	-7,22	medium_impact	2,54	neutral	0,91	damaging	0,13	deleterious	3,68	23,3	0,08	0,35	neutral	0,45	disease	0,77	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,05	medium_impact	0,99	0,41	0,8	NA	NA	N	0,34	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5307	5307	A	G	MI.14521	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	838	280	T	A	Acc/Gcc	-9,82	0	0	benign	0,34	neutral	0,5	neutral	4,22	neutral	0,71	deleterious	-3,64	medium_impact	2,45	neutral	0,9	neutral	0,69	deleterious	4,04	23,7	0,31	0,45	disease	0,74	neutral	0,4	neutral	0,38	disease	0,62	2	neutral	0,42	deleterious	0,58	neutral	-3	neutral	0,37	medium_impact	-0,53	medium_impact	0,21	medium_impact	0,92	0,36	0,8	1,44	7,46	N	0,38	N	0,75	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5307	5307	A	T	MI.14522	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	838	280	T	S	Acc/Tcc	-9,82	0	0	benign	0,04	neutral	0,42	neutral	4,12	neutral	-1,11	deleterious	-2,75	medium_impact	1,96	neutral	0,87	neutral	0,73	deleterious	2,83	21,5	0,36	0,5	disease	0,61	disease	0,52	neutral	0,35	neutral	0,23	5	neutral	0,55	deleterious	0,69	neutral	-3	neutral	0,21	medium_impact	0,47	medium_impact	0,13	medium_impact	0,51	0,54	0,8	1,44	7,46	N	0,33	N	0,34	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5307	5307	A	C	MI.14523	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	838	280	T	P	Acc/Ccc	-9,82	0	0	possibly_damaging	0,86	neutral	0,21	neutral	4,06	deleterious	-3	deleterious	-4,8	medium_impact	3,29	neutral	0,76	neutral	0,3	deleterious	4,11	23,7	0,05	0,35	disease	0,86	disease	0,8	disease	0,71	disease	0,66	3	neutral	0,91	neutral	0,18	NA	0	deleterious	0,73	low_impact	-1,52	medium_impact	-0,11	medium_impact	1,63	0,28	0,8	1,44	7,46	N	0,34	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5308	5308	C	T	MI.14524	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	839	280	T	I	aCc/aTc	0,13	0	0	possibly_damaging	0,45	neutral	0,43	neutral	4,21	neutral	0,25	deleterious	-4,32	low_impact	1,46	neutral	0,89	neutral	0,7	deleterious	3	22,2	0,11	0,4	disease	0,75	disease	0,68	neutral	0,36	neutral	0,24	5	neutral	0,53	deleterious	0,49	neutral	-3	deleterious	0,47	medium_impact	-0,72	medium_impact	0,14	medium_impact	0,09	0,64	0,8	1,44	7,46	N	0,38	N	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5308	5308	C	A	MI.14525	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	839	280	T	N	aCc/aAc	0,13	0	0	possibly_damaging	0,59	neutral	0,3	neutral	4,06	deleterious	-3,17	deleterious	-3,88	high_impact	4,1	neutral	0,84	neutral	0,46	deleterious	3,75	23,3	0,25	0,45	neutral	0,36	disease	0,69	disease	0,61	disease	0,64	3	neutral	0,71	neutral	0,36	deleterious	1	deleterious	0,49	medium_impact	-0,94	medium_impact	0	high_impact	2,31	0,5	0,8	1,44	7,46	N	0,44	N	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5308	5308	C	G	MI.14526	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	839	280	T	S	aCc/aGc	0,13	0	0	benign	0,04	neutral	0,42	neutral	4,12	neutral	-1,11	deleterious	-2,75	medium_impact	1,96	neutral	0,87	neutral	0,73	deleterious	2,46	19,2	0,36	0,5	disease	0,61	disease	0,52	neutral	0,35	neutral	0,23	5	neutral	0,55	deleterious	0,69	neutral	-3	neutral	0,21	medium_impact	0,47	medium_impact	0,13	medium_impact	0,51	0,54	0,8	1,44	7,46	N	0,33	N	0,34	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5310	5310	A	G	MI.14527	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	841	281	I	V	Atc/Gtc	-7,51	0	0	benign	0,01	neutral	0,48	neutral	4,19	neutral	-0,03	neutral	-0,61	neutral_impact	0,8	neutral	0,98	neutral	0,95	deleterious	0,04	3,01	0,42	0,55	neutral	0,48	neutral	0,2	neutral	0,31	neutral	0,33	3	neutral	0,5	deleterious	0,74	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,19	medium_impact	-0,47	0,5	0,8	2,31	8,33	N	0,4	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5310	5310	A	C	MI.14528	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	841	281	I	L	Atc/Ctc	-7,51	0	0	benign	0,04	neutral	1	neutral	4,2	neutral	-0,29	neutral	0,26	neutral_impact	-0,1	neutral	0,89	neutral	0,97	neutral	-0,72	0,06	0,18	0,45	neutral	0,41	neutral	0,26	neutral	0,2	neutral	0,45	1	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,12	medium_impact	0,47	high_impact	1,87	low_impact	-1,23	0,52	0,8	2,31	8,33	N	0,32	N	0,22	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5310	5310	A	T	MI.14529	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	841	281	I	F	Atc/Ttc	-7,51	0	0	benign	0,39	neutral	0,71	neutral	3,98	neutral	-2,07	neutral	-1,66	low_impact	0,82	neutral	0,91	neutral	0,94	deleterious	0,83	9,65	0,16	0,45	disease	0,68	disease	0,54	neutral	0,32	neutral	0,25	5	neutral	0,29	deleterious	0,66	neutral	-6	neutral	0,37	medium_impact	-0,62	medium_impact	0,42	medium_impact	-0,45	0,48	0,8	2,31	8,33	N	0,26	N	0,21	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8369	8369	C	G	MI.1453	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	4	2	P	A	Ccc/Gcc	5,22	1	0	probably_damaging	0,99	deleterious	0,01	neutral	-1,21	deleterious	-8,92	deleterious	-7,95	high_impact	3,9	neutral	0,99	neutral	0,51	deleterious	2,85	21,6	0,40681744	0,85	disease	0,76	neutral	0,06	disease	0,53	neutral	0,16	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,65	medium_impact	-0,84	high_impact	2,25	0,4	0,85	22,06	7,2	P	0,64	P	0,83	disease_causing	0,96	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5311	5311	T	G	MI.14530	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	842	281	I	S	aTc/aGc	-7,05	0	0	benign	0,14	neutral	0,39	neutral	3,94	deleterious	-3,04	deleterious	-3,24	medium_impact	1,97	neutral	0,87	neutral	0,88	neutral	1,32	12,35	0,05	0,35	disease	0,71	disease	0,69	neutral	0,41	neutral	0,37	3	neutral	0,54	deleterious	0,63	neutral	-3	neutral	0,3	medium_impact	-0,08	medium_impact	0,1	medium_impact	0,51	0,28	0,8	2,31	8,33	N	0,33	N	0,47	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5311	5311	T	C	MI.14531	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	842	281	I	T	aTc/aCc	-7,05	0	0	benign	0	neutral	0,59	neutral	3,96	neutral	-2,62	neutral	-2,24	low_impact	1,38	neutral	0,97	neutral	0,99	deleterious	0,07	3,26	0,12	0,4	disease	0,72	neutral	0,34	neutral	0,35	disease	0,64	3	neutral	0,4	deleterious	0,8	neutral	-6	neutral	0,19	medium_impact	1,95	medium_impact	0,3	medium_impact	0,02	0,3	0,8	2,31	8,33	N	0,3	N	0,14	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5311	5311	T	A	MI.14532	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	842	281	I	N	aTc/aAc	-7,05	0	0	benign	0,39	neutral	0,32	neutral	3,91	deleterious	-4,42	deleterious	-4,27	high_impact	3,6	neutral	0,89	neutral	0,41	deleterious	2,66	20,6	0,09	0,35	disease	0,93	disease	0,68	disease	0,6	disease	0,7	4	neutral	0,62	neutral	0,47	neutral	-2	deleterious	0,55	medium_impact	-0,62	medium_impact	0,03	medium_impact	1,89	0,36	0,8	2,31	8,33	N	0,39	N	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5312	5312	C	A	MI.14533	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	843	281	I	M	atC/atA	-0,11	0	0	benign	0,02	neutral	0,38	neutral	3,97	neutral	-2,48	neutral	-0,59	low_impact	1,75	neutral	0,9	neutral	0,96	neutral	0,99	10,62	0,29	0,45	disease	0,65	neutral	0,29	neutral	0,25	disease	0,56	1	neutral	0,6	deleterious	0,68	neutral	-6	neutral	0,16	medium_impact	0,75	medium_impact	0,09	medium_impact	0,33	0,53	0,8	2,31	8,33	N	0,46	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5312	5312	C	G	MI.14534	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	843	281	I	M	atC/atG	-0,11	0	0	benign	0,02	neutral	0,38	neutral	3,97	neutral	-2,48	neutral	-0,59	low_impact	1,75	neutral	0,9	neutral	0,96	deleterious	0,47	7,17	0,29	0,45	disease	0,65	neutral	0,29	neutral	0,25	disease	0,56	1	neutral	0,6	deleterious	0,68	neutral	-6	neutral	0,16	medium_impact	0,75	medium_impact	0,09	medium_impact	0,33	0,53	0,8	2,31	8,33	N	0,45	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5313	5313	A	C	MI.14535	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	844	282	M	L	Ata/Cta	-13,29	0	0	probably_damaging	0,96	neutral	1	neutral	4,4	neutral	1,6	deleterious	-2,72	low_impact	0,91	neutral	0,94	neutral	0,86	deleterious	1,91	15,66	0,27	0,45	disease	0,57	disease	0,69	neutral	0,43	neutral	0,23	5	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,69	low_impact	-2,06	high_impact	1,87	medium_impact	-0,38	0,26	0,8	NA	NA	N	0,25	N	0,37	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5313	5313	A	G	MI.14536	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	844	282	M	V	Ata/Gta	-13,29	0	0	probably_damaging	0,98	neutral	0,34	neutral	4,24	neutral	0,6	deleterious	-3,69	medium_impact	2,72	neutral	0,84	damaging	0,15	deleterious	2,53	19,69	0,22	0,45	neutral	0,42	disease	0,71	disease	0,57	disease	0,54	1	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,73	low_impact	-2,34	medium_impact	0,05	medium_impact	1,15	0,31	0,8	NA	NA	N	0,24	N	0,74	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5313	5313	A	T	MI.14537	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	844	282	M	L	Ata/Tta	-13,29	0	0	probably_damaging	0,96	neutral	1	neutral	4,4	neutral	1,6	deleterious	-2,72	low_impact	0,91	neutral	0,94	neutral	0,86	deleterious	1,98	16,09	0,27	0,45	disease	0,57	disease	0,69	neutral	0,43	neutral	0,23	5	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,69	low_impact	-2,06	high_impact	1,87	medium_impact	-0,38	0,26	0,8	NA	NA	N	0,27	N	0,37	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5314	5314	T	A	MI.14538	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	845	282	M	K	aTa/aAa	1,28	0,57	0	probably_damaging	0,99	neutral	0,24	neutral	4,11	neutral	-2,48	deleterious	-5,68	high_impact	4,22	neutral	0,81	damaging	0,12	deleterious	3,94	23,5	0,04	0,35	disease	0,88	disease	0,88	disease	0,72	disease	0,65	3	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,87	low_impact	-2,62	medium_impact	-0,07	high_impact	2,41	0,22	0,8	NA	NA	N	0,39	N	0,93	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5314	5314	T	C	MI.14539	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	845	282	M	T	aTa/aCa	1,28	0,57	0	probably_damaging	0,99	neutral	0,39	neutral	4,15	neutral	-1,03	deleterious	-5,63	medium_impact	3,07	neutral	0,83	damaging	0,16	deleterious	2,94	22	0,09	0,35	disease	0,72	disease	0,77	disease	0,58	disease	0,55	1	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,81	low_impact	-2,62	medium_impact	0,1	medium_impact	1,44	0,13	0,8	NA	NA	N	0,29	N	0,88	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8370	8370	C	T	MI.1454	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	5	2	P	L	cCc/cTc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	-1,23	deleterious	-11,38	deleterious	-9,94	high_impact	3,9	neutral	1	neutral	0,38	deleterious	4,19	23,9	0,42878708	0,85	disease	0,87	neutral	0,13	disease	0,53	neutral	0,22	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,6	low_impact	-1,4	high_impact	2,25	0,63	0,85	22,06	7,2	P	0,64	P	0,92	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5315	5315	A	C	MI.14540	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	846	282	M	I	atA/atC	4,29	0,77	0,01	probably_damaging	0,98	neutral	0,63	neutral	4,27	neutral	0,67	deleterious	-3,65	medium_impact	2,25	neutral	0,85	neutral	0,41	deleterious	3,19	22,7	0,24	0,45	neutral	0,43	neutral	0,31	neutral	0,39	neutral	0,44	1	deleterious	0,98	neutral	0,33	deleterious	1	deleterious	0,7	low_impact	-2,34	medium_impact	0,34	medium_impact	0,75	0,27	0,8	NA	NA	N	0,34	N	0,75	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5315	5315	A	T	MI.14541	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	846	282	M	I	atA/atT	4,29	0,77	0,01	probably_damaging	0,98	neutral	0,63	neutral	4,27	neutral	0,67	deleterious	-3,65	medium_impact	2,25	neutral	0,85	neutral	0,41	deleterious	3,3	22,9	0,24	0,45	neutral	0,43	neutral	0,31	neutral	0,39	neutral	0,44	1	deleterious	0,98	neutral	0,33	deleterious	1	deleterious	0,7	low_impact	-2,34	medium_impact	0,34	medium_impact	0,75	0,27	0,8	NA	NA	N	0,35	N	0,75	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5316	5316	G	C	MI.14542	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	847	283	A	P	Gcc/Ccc	-1,03	0	0	possibly_damaging	0,86	neutral	0,2	neutral	3,94	deleterious	-4,73	deleterious	-4,33	high_impact	3,62	neutral	0,77	neutral	0,32	deleterious	3,88	23,5	0,04	0,35	disease	0,98	disease	0,91	disease	0,7	disease	0,7	4	neutral	0,91	neutral	0,17	deleterious	1	deleterious	0,79	low_impact	-1,52	medium_impact	-0,13	medium_impact	1,9	0,49	0,8	NA	NA	N	0,38	N	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5316	5316	G	A	MI.14543	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	847	283	A	T	Gcc/Acc	-1,03	0	0	benign	0,04	neutral	0,39	neutral	3,99	neutral	-2,21	deleterious	-3,09	medium_impact	2,41	neutral	0,95	neutral	0,84	deleterious	3,18	22,7	0,16	0,45	disease	0,92	disease	0,71	neutral	0,44	disease	0,58	2	neutral	0,58	deleterious	0,68	neutral	-3	neutral	0,32	medium_impact	0,47	medium_impact	0,1	medium_impact	0,88	0,42	0,8	NA	NA	N	0,36	N	0,56	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5316	5316	G	T	MI.14544	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	847	283	A	S	Gcc/Tcc	-1,03	0	0	possibly_damaging	0,45	neutral	0,4	neutral	3,99	neutral	-2,62	deleterious	-2,58	medium_impact	2,79	neutral	0,79	neutral	0,72	deleterious	3,7	23,3	0,23	0,45	disease	0,87	disease	0,54	neutral	0,33	neutral	0,47	1	neutral	0,56	deleterious	0,48	NA	0	deleterious	0,52	medium_impact	-0,72	medium_impact	0,11	medium_impact	1,2	0,28	0,8	NA	NA	N	0,33	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5317	5317	C	G	MI.14545	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	848	283	A	G	gCc/gGc	1,05	0	0	possibly_damaging	0,54	neutral	0,32	neutral	4,01	neutral	-1,54	deleterious	-3,65	medium_impact	3,48	neutral	0,89	neutral	0,58	deleterious	4,03	23,6	0,2	0,45	disease	0,95	disease	0,79	disease	0,56	disease	0,67	3	neutral	0,67	neutral	0,39	NA	0	deleterious	0,59	medium_impact	-0,86	medium_impact	0,03	medium_impact	1,79	0,49	0,8	NA	NA	N	0,46	N	0,68	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5317	5317	C	A	MI.14546	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	848	283	A	D	gCc/gAc	1,05	0	0	possibly_damaging	0,74	neutral	0,2	neutral	3,93	deleterious	-5,32	deleterious	-5,22	high_impact	4,17	neutral	0,83	neutral	0,35	deleterious	4,69	24,6	0,03	0,35	disease	0,98	disease	0,91	disease	0,69	disease	0,7	4	neutral	0,85	neutral	0,23	deleterious	1	deleterious	0,75	low_impact	-1,21	medium_impact	-0,13	high_impact	2,37	0,36	0,8	NA	NA	N	0,4	N	0,93	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5317	5317	C	T	MI.14547	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	848	283	A	V	gCc/gTc	1,05	0	0	benign	0,04	neutral	0,49	neutral	4,16	neutral	-0,27	deleterious	-2,87	low_impact	1,78	neutral	0,96	neutral	0,67	deleterious	4,44	24,2	0,15	0,4	disease	0,91	disease	0,82	neutral	0,47	disease	0,55	1	neutral	0,47	deleterious	0,73	neutral	-6	neutral	0,33	medium_impact	0,47	medium_impact	0,2	medium_impact	0,35	0,43	0,8	NA	NA	N	0,29	N	0,58	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5319	5319	A	T	MI.14548	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	850	284	T	S	Acc/Tcc	-13,06	0	0,02	benign	0,02	neutral	0,29	neutral	4,19	neutral	-0,72	neutral	-0,95	neutral_impact	0,27	neutral	0,9	neutral	0,62	deleterious	1,98	16,07	0,4	0,5	disease	0,6	neutral	0,35	neutral	0,44	disease	0,6	2	neutral	0,7	deleterious	0,64	neutral	-6	neutral	0,18	medium_impact	0,75	medium_impact	-0,01	medium_impact	-0,92	0,42	0,8	NA	NA	N	0,43	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5319	5319	A	C	MI.14549	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	850	284	T	P	Acc/Ccc	-13,06	0	0,02	benign	0,12	neutral	0,05	neutral	4,12	deleterious	-3,38	neutral	-1,92	low_impact	1,27	neutral	0,85	neutral	0,44	deleterious	2,13	17,05	0,06	0,35	disease	0,79	disease	0,8	disease	0,58	disease	0,73	5	neutral	0,94	neutral	0,47	neutral	-6	neutral	0,34	medium_impact	-0,01	medium_impact	-0,5	medium_impact	-0,08	0,29	0,8	NA	NA	N	0,32	N	0,34	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8370	8370	C	G	MI.1455	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	5	2	P	R	cCc/cGc	5,45	1	0	probably_damaging	1	deleterious	0,02	neutral	-1,23	deleterious	-11,45	deleterious	-8,94	high_impact	3,9	neutral	1	neutral	0,35	deleterious	3,34	22,9	0,34743468	0,85	disease	0,88	neutral	0,14	disease	0,59	neutral	0,23	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,6	medium_impact	-0,66	high_impact	2,25	0,29	0,85	22,06	7,2	P	0,64	P	0,8	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5319	5319	A	G	MI.14550	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	850	284	T	A	Acc/Gcc	-13,06	0	0,02	benign	0	neutral	0,2	neutral	4,23	neutral	0,04	neutral	-0,38	neutral_impact	0,46	neutral	0,97	neutral	0,87	deleterious	2,1	16,83	0,23	0,45	neutral	0,49	neutral	0,28	neutral	0,45	neutral	0,4	2	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	-0,13	medium_impact	-0,76	0,28	0,8	NA	NA	N	0,38	N	0,24	polymorphism	1	0,01	rs28456039	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5320	5320	C	T	MI.14551	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	851	284	T	I	aCc/aTc	-0,34	0	0	benign	0	neutral	0,45	neutral	4,31	neutral	0,71	neutral	2,84	neutral_impact	-1,59	neutral	0,97	neutral	0,99	neutral	-0,61	0,12	0,13	0,4	neutral	0,42	neutral	0,26	neutral	0,18	neutral	0,44	1	neutral	0,55	deleterious	0,73	neutral	-6	neutral	0,13	medium_impact	1,95	medium_impact	0,16	low_impact	-2,48	0,5	0,8	NA	NA	N	0,35	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5320	5320	C	G	MI.14552	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	851	284	T	S	aCc/aGc	-0,34	0	0	benign	0,02	neutral	0,29	neutral	4,19	neutral	-0,72	neutral	-0,95	neutral_impact	0,27	neutral	0,9	neutral	0,62	neutral	1,65	14,14	0,4	0,5	disease	0,6	neutral	0,35	neutral	0,44	disease	0,6	2	neutral	0,7	deleterious	0,64	neutral	-6	neutral	0,18	medium_impact	0,75	medium_impact	-0,01	medium_impact	-0,92	0,42	0,8	NA	NA	N	0,43	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5320	5320	C	A	MI.14553	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	851	284	T	N	aCc/aAc	-0,34	0	0	benign	0,12	deleterious	0,04	neutral	4,13	neutral	-2,84	neutral	-1,91	low_impact	1,82	neutral	0,83	neutral	0,63	deleterious	1,84	15,25	0,24	0,45	disease	0,76	disease	0,58	neutral	0,46	neutral	0,49	0	neutral	0,96	neutral	0,46	neutral	-2	neutral	0,26	medium_impact	-0,01	medium_impact	-0,56	medium_impact	0,39	0,52	0,8	NA	NA	N	0,38	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5322	5322	A	G	MI.14554	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	853	285	I	V	Atc/Gtc	-16,07	0	0	benign	0	neutral	0,51	neutral	4,26	neutral	0,36	neutral	-0,1	neutral_impact	0,22	neutral	0,96	neutral	0,72	deleterious	0,03	2,93	0,4	0,5	neutral	0,5	neutral	0,19	neutral	0,33	neutral	0,28	4	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,22	medium_impact	-0,96	0,34	0,8	1,15	6,87	N	0,37	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5322	5322	A	T	MI.14555	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	853	285	I	F	Atc/Ttc	-16,07	0	0	benign	0,27	neutral	0,76	neutral	4,18	neutral	-0,85	neutral	-1,34	neutral_impact	-0,2	neutral	0,93	neutral	0,77	neutral	1,04	10,86	0,21	0,45	disease	0,7	neutral	0,49	neutral	0,23	neutral	0,49	0	neutral	0,18	deleterious	0,75	neutral	-6	neutral	0,37	medium_impact	-0,4	medium_impact	0,49	low_impact	-1,31	0,4	0,8	1,15	6,87	N	0,25	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5322	5322	A	C	MI.14556	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	853	285	I	L	Atc/Ctc	-16,07	0	0	benign	0	neutral	0,91	neutral	4,27	neutral	0,22	neutral	0,84	neutral_impact	-1,67	neutral	0,93	neutral	0,94	neutral	-0,74	0,06	0,24	0,45	neutral	0,37	neutral	0,13	neutral	0,14	neutral	0,23	6	neutral	0,07	deleterious	0,96	neutral	-6	neutral	0,1	medium_impact	1,95	medium_impact	0,77	low_impact	-2,55	0,43	0,8	1,15	6,87	N	0,4	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5323	5323	T	G	MI.14557	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	854	285	I	S	aTc/aGc	-3,11	0	0	benign	0,14	neutral	0,55	neutral	4,24	neutral	-0,18	neutral	-1,05	neutral_impact	-2,35	neutral	0,82	neutral	0,97	deleterious	0,5	7,46	0,07	0,35	disease	0,76	neutral	0,16	neutral	0,24	neutral	0,45	1	neutral	0,35	deleterious	0,71	neutral	-6	neutral	0,2	medium_impact	-0,08	medium_impact	0,26	low_impact	-3,12	0,22	0,8	1,15	6,87	N	0,31	N	0,19	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5323	5323	T	A	MI.14558	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	854	285	I	N	aTc/aAc	-3,11	0	0	possibly_damaging	0,55	neutral	0,32	neutral	4,17	neutral	-0,32	neutral	-2,18	neutral_impact	-0,22	neutral	0,86	neutral	0,52	deleterious	2,75	21,1	0,14	0,4	disease	0,7	disease	0,58	neutral	0,37	neutral	0,41	2	neutral	0,67	neutral	0,39	neutral	-3	deleterious	0,56	medium_impact	-0,88	medium_impact	0,03	low_impact	-1,33	0,2	0,8	1,15	6,87	N	0,29	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5323	5323	T	C	MI.14559	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	854	285	I	T	aTc/aCc	-3,11	0	0	benign	0,14	neutral	0,65	neutral	4,23	neutral	-0,42	neutral	0,17	neutral_impact	-2,22	neutral	0,9	neutral	0,96	neutral	-0,69	0,07	0,19	0,45	neutral	0,45	neutral	0,13	neutral	0,23	neutral	0,28	4	neutral	0,24	deleterious	0,76	neutral	-6	neutral	0,22	medium_impact	-0,08	medium_impact	0,36	low_impact	-3,01	0,35	0,8	1,15	6,87	N	0,36	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8370	8370	C	A	MI.1456	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	5	2	P	H	cCc/cAc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	-1,23	deleterious	-12,48	deleterious	-8,94	high_impact	3,9	neutral	0,95	neutral	0,34	deleterious	3,75	23,3	0,33487573	0,85	disease	0,93	neutral	0,16	disease	0,6	neutral	0,26	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,6	low_impact	-1,4	high_impact	2,25	0,22	0,85	22,06	7,2	P	0,63	P	0,84	disease_causing	0,99	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5324	5324	C	G	MI.14560	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	855	285	I	M	atC/atG	0,36	0	0	benign	0,01	neutral	0,27	neutral	4,16	neutral	-0,99	neutral	0,88	neutral_impact	-0,99	neutral	0,97	neutral	0,92	neutral	-0,41	0,37	0,3	0,45	disease	0,55	neutral	0,18	neutral	0,17	neutral	0,4	2	neutral	0,72	deleterious	0,63	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	-0,03	low_impact	-1,98	0,53	0,8	1,15	6,87	N	0,46	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5324	5324	C	A	MI.14561	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	855	285	I	M	atC/atA	0,36	0	0	benign	0,01	neutral	0,27	neutral	4,16	neutral	-0,99	neutral	0,88	neutral_impact	-0,99	neutral	0,97	neutral	0,92	deleterious	0,04	2,95	0,3	0,45	disease	0,55	neutral	0,18	neutral	0,17	neutral	0,4	2	neutral	0,72	deleterious	0,63	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	-0,03	low_impact	-1,98	0,53	0,8	1,15	6,87	N	0,46	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5325	5325	A	C	MI.14562	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	856	286	T	P	Acc/Ccc	-2,19	0	0	probably_damaging	0,93	neutral	0,19	neutral	4,01	deleterious	-3,87	neutral	-1,9	medium_impact	2,16	neutral	0,75	neutral	0,39	deleterious	3,13	22,6	0,04	0,35	disease	0,73	disease	0,89	disease	0,73	disease	0,75	5	neutral	0,96	neutral	0,13	deleterious	1	deleterious	0,81	low_impact	-1,83	medium_impact	-0,14	medium_impact	0,67	0,28	0,8	NA	NA	N	0,3	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5325	5325	A	G	MI.14563	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	856	286	T	A	Acc/Gcc	-2,19	0	0	benign	0,04	neutral	0,73	neutral	4,17	neutral	-0,31	neutral	2,04	neutral_impact	-1,54	neutral	0,9	neutral	0,96	neutral	-1,04	0,01	0,21	0,45	disease	0,68	neutral	0,07	neutral	0,27	neutral	0,31	4	neutral	0,21	deleterious	0,85	neutral	-6	neutral	0,19	medium_impact	0,47	medium_impact	0,45	low_impact	-2,44	0,32	0,8	NA	NA	N	0,29	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5325	5325	A	T	MI.14564	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	856	286	T	S	Acc/Tcc	-2,19	0	0	benign	0,1	neutral	0,57	neutral	4,46	neutral	1,09	neutral	0,13	neutral_impact	-0,88	neutral	0,87	neutral	0,95	deleterious	0,33	6,03	0,39	0,5	neutral	0,48	neutral	0,1	neutral	0,34	neutral	0,3	4	neutral	0,34	deleterious	0,74	neutral	-6	neutral	0,22	medium_impact	0,08	medium_impact	0,28	low_impact	-1,89	0,6	0,8	NA	NA	N	0,36	N	0,35	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5326	5326	C	A	MI.14565	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	857	286	T	N	aCc/aAc	2,44	0,99	0	possibly_damaging	0,69	neutral	0,34	neutral	4,02	neutral	-2,95	neutral	-2,38	low_impact	1,62	neutral	0,83	neutral	0,59	deleterious	1,91	15,65	0,27	0,45	disease	0,95	disease	0,76	disease	0,62	disease	0,73	5	neutral	0,74	neutral	0,33	neutral	-3	deleterious	0,75	low_impact	-1,12	medium_impact	0,05	medium_impact	0,22	0,45	0,8	NA	NA	N	0,47	N	0,71	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5326	5326	C	G	MI.14566	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	857	286	T	S	aCc/aGc	2,44	0,99	0	benign	0,1	neutral	0,57	neutral	4,46	neutral	1,09	neutral	0,13	neutral_impact	-0,88	neutral	0,87	neutral	0,95	deleterious	0,57	7,97	0,39	0,5	neutral	0,48	neutral	0,1	neutral	0,34	neutral	0,3	4	neutral	0,34	deleterious	0,74	neutral	-6	neutral	0,22	medium_impact	0,08	medium_impact	0,28	low_impact	-1,89	0,6	0,8	NA	NA	N	0,43	N	0,35	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5326	5326	C	T	MI.14567	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	857	286	T	I	aCc/aTc	2,44	0,99	0	possibly_damaging	0,87	neutral	0,51	neutral	4,06	neutral	-1,72	neutral	-1,94	medium_impact	2,16	neutral	0,86	neutral	0,54	deleterious	2,45	19,15	0,12	0,4	disease	0,9	disease	0,74	disease	0,59	disease	0,69	4	neutral	0,86	neutral	0,32	NA	0	deleterious	0,77	low_impact	-1,55	medium_impact	0,22	medium_impact	0,67	0,63	0,8	NA	NA	N	0,44	N	0,7	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5328	5328	C	T	MI.14568	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	859	287	L	F	Ctc/Ttc	-10,98	0	0	probably_damaging	1	neutral	0,29	neutral	3,92	neutral	-2,66	deleterious	-3,83	high_impact	3,67	neutral	0,68	damaging	0,04	deleterious	4,03	23,6	0,19	0,45	disease	0,85	disease	0,68	disease	0,67	disease	0,64	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,01	medium_impact	1,95	0,51	0,8	NA	NA	N	0,32	N	0,98	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5328	5328	C	G	MI.14569	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	859	287	L	V	Ctc/Gtc	-10,98	0	0	probably_damaging	1	neutral	0,14	neutral	4,2	neutral	0,09	deleterious	-2,87	medium_impact	2,74	neutral	0,66	damaging	0,05	deleterious	3,5	23,1	0,33	0,5	neutral	0,39	disease	0,57	disease	0,57	disease	0,62	2	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	-0,23	medium_impact	1,16	0,46	0,8	NA	NA	N	0,3	N	0,73	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8372	8372	C	A	MI.1457	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	7	3	Q	K	Caa/Aaa	-2,19	0	0	probably_damaging	0,94	deleterious	0	deleterious	-2,65	deleterious	-12,55	deleterious	-3,99	high_impact	3,9	neutral	0,84	damaging	0,06	deleterious	3,77	23,4	0,43104827	0,85	disease	0,59	neutral	0,14	neutral	0,46	neutral	0,21	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,7	low_impact	-1,89	low_impact	-1,4	high_impact	2,25	0,43	0,85	23,53	8,05	N	0,48	N	0,85	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5328	5328	C	A	MI.14570	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	859	287	L	I	Ctc/Atc	-10,98	0	0	probably_damaging	1	neutral	0,24	neutral	4	neutral	-0,99	neutral	-1,92	medium_impact	3,12	neutral	0,7	damaging	0,05	deleterious	4,14	23,8	0,32	0,5	neutral	0,39	disease	0,59	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	-0,07	medium_impact	1,48	0,54	0,8	NA	NA	N	0,35	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5329	5329	T	G	MI.14571	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	860	287	L	R	cTc/cGc	0,82	0,39	0	probably_damaging	1	neutral	0,12	neutral	3,87	deleterious	-4,22	deleterious	-5,74	high_impact	4,71	damaging	0,56	damaging	0,05	deleterious	4,29	24	0,02	0,35	disease	0,91	disease	0,87	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	-0,27	high_impact	2,82	0,17	0,8	NA	NA	P	0,66	P	0,99	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5329	5329	T	C	MI.14572	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	860	287	L	P	cTc/cCc	0,82	0,39	0	probably_damaging	1	deleterious	0,02	neutral	3,86	deleterious	-4,79	deleterious	-6,7	high_impact	4,71	damaging	0,53	damaging	0,04	deleterious	4	23,6	0,03	0,35	disease	0,94	disease	0,77	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-3,54	medium_impact	-0,73	high_impact	2,82	0,33	0,8	NA	NA	P	0,6	P	0,99	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5329	5329	T	A	MI.14573	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	860	287	L	H	cTc/cAc	0,82	0,39	0	probably_damaging	1	neutral	0,08	neutral	3,86	deleterious	-4,75	deleterious	-6,7	high_impact	4,71	neutral	0,69	damaging	0,04	deleterious	4,21	23,9	0,05	0,35	disease	0,93	disease	0,77	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,38	high_impact	2,82	0,27	0,8	NA	NA	P	0,62	P	0,97	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5331	5331	C	T	MI.14574	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	862	288	L	F	Ctt/Ttt	-4,04	0	0	possibly_damaging	0,49	neutral	0,39	neutral	4	neutral	-2,13	deleterious	-3,74	medium_impact	2,8	neutral	0,87	neutral	0,47	deleterious	2,2	17,48	0,26	0,45	disease	0,81	disease	0,68	disease	0,55	disease	0,63	3	neutral	0,59	neutral	0,45	NA	0	deleterious	0,62	medium_impact	-0,78	medium_impact	0,1	medium_impact	1,21	0,51	0,8	NA	NA	N	0,36	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5331	5331	C	A	MI.14575	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	862	288	L	I	Ctt/Att	-4,04	0	0	benign	0,01	neutral	0,48	neutral	4,27	neutral	0,09	neutral	-1,83	low_impact	1,38	neutral	0,89	neutral	0,79	neutral	1,17	11,59	0,3	0,45	disease	0,76	neutral	0,5	neutral	0,32	neutral	0,3	4	neutral	0,51	deleterious	0,74	neutral	-6	neutral	0,24	medium_impact	1,03	medium_impact	0,19	medium_impact	0,02	0,37	0,8	NA	NA	N	0,28	N	0,83	polymorphism	1	0,04	rs200778062	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5331	5331	C	G	MI.14576	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	862	288	L	V	Ctt/Gtt	-4,04	0	0	benign	0,01	neutral	0,24	neutral	4,11	neutral	-0,64	deleterious	-2,75	medium_impact	2,44	neutral	0,93	neutral	0,59	neutral	1,56	13,62	0,3	0,45	disease	0,7	disease	0,58	disease	0,53	disease	0,58	2	neutral	0,75	deleterious	0,62	neutral	-3	neutral	0,25	medium_impact	1,03	medium_impact	-0,07	medium_impact	0,91	0,48	0,8	NA	NA	N	0,37	N	0,73	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5332	5332	T	C	MI.14577	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	863	288	L	P	cTt/cCt	-1,26	0	0	possibly_damaging	0,75	neutral	0,07	neutral	3,9	deleterious	-4,94	deleterious	-6,58	medium_impact	2,62	neutral	0,88	neutral	0,59	deleterious	2,15	17,16	0,06	0,35	disease	0,87	disease	0,74	disease	0,71	disease	0,57	1	neutral	0,95	neutral	0,16	NA	0	deleterious	0,72	low_impact	-1,23	medium_impact	-0,42	medium_impact	1,06	0,27	0,8	NA	NA	N	0,42	N	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5332	5332	T	G	MI.14578	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	863	288	L	R	cTt/cGt	-1,26	0	0	possibly_damaging	0,75	neutral	0,14	neutral	3,9	deleterious	-4,37	deleterious	-5,63	high_impact	4,39	neutral	0,87	neutral	0,37	deleterious	2,49	19,4	0,05	0,35	disease	0,76	disease	0,87	disease	0,75	disease	0,73	5	neutral	0,9	neutral	0,2	deleterious	1	deleterious	0,73	low_impact	-1,23	medium_impact	-0,23	high_impact	2,55	0,19	0,8	NA	NA	N	0,51	P	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5332	5332	T	A	MI.14579	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	863	288	L	H	cTt/cAt	-1,26	0	0	possibly_damaging	0,9	neutral	0,18	neutral	3,9	deleterious	-4,89	deleterious	-6,58	high_impact	4,04	neutral	0,89	neutral	0,37	deleterious	3,85	23,4	0,07	0,35	disease	0,86	disease	0,77	disease	0,72	disease	0,69	4	neutral	0,94	neutral	0,14	deleterious	1	deleterious	0,76	low_impact	-1,67	medium_impact	-0,16	high_impact	2,26	0,25	0,8	NA	NA	N	0,47	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8372	8372	C	G	MI.1458	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	7	3	Q	E	Caa/Gaa	-2,19	0	0	possibly_damaging	0,87	deleterious	0	deleterious	-2,65	deleterious	-12,77	deleterious	-2,99	high_impact	3,9	neutral	0,75	damaging	0,08	deleterious	2,85	21,6	0,45913084	0,85	disease	0,64	neutral	0,11	neutral	0,46	neutral	0,22	6	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,68	low_impact	-1,54	low_impact	-1,4	high_impact	2,25	0,36	0,85	23,53	8,05	N	0,44	N	0,73	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5334	5334	A	C	MI.14580	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	865	289	N	H	Aac/Cac	-5,89	0	0	probably_damaging	1	neutral	0,54	neutral	4,19	neutral	-1,73	deleterious	-4,63	medium_impact	3,05	neutral	0,85	damaging	0,11	deleterious	3,17	22,7	0,34	0,5	neutral	0,39	disease	0,64	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	0,25	medium_impact	1,42	0,2	0,8	NA	NA	N	0,21	N	0,86	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5334	5334	A	G	MI.14581	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	865	289	N	D	Aac/Gac	-5,89	0	0	probably_damaging	1	neutral	0,21	neutral	4,21	neutral	-0,98	deleterious	-4,58	high_impact	3,75	neutral	0,83	damaging	0,12	deleterious	3,89	23,5	0,46	0,55	disease	0,71	disease	0,7	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	-0,11	high_impact	2,01	0,36	0,8	NA	NA	N	0,32	N	0,91	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5334	5334	A	T	MI.14582	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	865	289	N	Y	Aac/Tac	-5,89	0	0	probably_damaging	1	neutral	1	neutral	4,2	neutral	-1,37	deleterious	-7,4	medium_impact	3,4	neutral	0,89	damaging	0,11	deleterious	3,8	23,4	0,09	0,4	disease	0,72	disease	0,76	disease	0,65	disease	0,69	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,81	low_impact	-3,54	high_impact	1,87	medium_impact	1,72	0,18	0,8	NA	NA	N	0,23	N	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5335	5335	A	G	MI.14583	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	866	289	N	S	aAc/aGc	2,44	0,91	0	probably_damaging	1	neutral	0,42	neutral	4,55	neutral	2,35	deleterious	-4,38	neutral_impact	0,04	neutral	0,84	neutral	0,83	neutral	1,67	14,27	0,46	0,55	disease	0,52	neutral	0,08	neutral	0,37	neutral	0,2	6	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,7	low_impact	-3,54	medium_impact	0,13	low_impact	-1,11	0,31	0,8	NA	NA	N	0,43	N	0,6	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5335	5335	A	C	MI.14584	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	866	289	N	T	aAc/aCc	2,44	0,91	0	probably_damaging	1	neutral	0,39	neutral	4,38	neutral	1,4	deleterious	-5,44	low_impact	1,27	neutral	0,85	damaging	0,18	deleterious	3,44	23	0,3	0,45	disease	0,7	disease	0,55	disease	0,65	disease	0,61	2	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	0,1	medium_impact	-0,08	0,3	0,8	NA	NA	N	0,33	N	0,87	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5335	5335	A	T	MI.14585	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	866	289	N	I	aAc/aTc	2,44	0,91	0	probably_damaging	1	neutral	0,4	neutral	4,22	neutral	-0,49	deleterious	-8,31	medium_impact	3,19	neutral	0,86	damaging	0,12	deleterious	3,98	23,6	0,12	0,4	disease	0,85	disease	0,8	disease	0,61	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,11	medium_impact	1,54	0,2	0,8	NA	NA	N	0,37	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5336	5336	C	A	MI.14586	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	867	289	N	K	aaC/aaA	3,83	0,97	0	probably_damaging	1	neutral	0,3	neutral	4,23	neutral	-0,11	deleterious	-5,49	high_impact	3,75	neutral	0,85	damaging	0,11	deleterious	4,54	24,3	0,34	0,5	disease	0,6	disease	0,76	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0	high_impact	2,01	0,43	0,8	NA	NA	N	0,48	N	0,93	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5336	5336	C	G	MI.14587	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	867	289	N	K	aaC/aaG	3,83	0,97	0	probably_damaging	1	neutral	0,3	neutral	4,23	neutral	-0,11	deleterious	-5,49	high_impact	3,75	neutral	0,85	damaging	0,11	deleterious	4,07	23,7	0,34	0,5	disease	0,6	disease	0,76	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0	high_impact	2,01	0,43	0,8	NA	NA	N	0,49	N	0,93	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5337	5337	C	G	MI.14588	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	868	290	L	V	Ctc/Gtc	-0,11	0,02	0	probably_damaging	1	neutral	0,2	neutral	-0,79	deleterious	-7,71	deleterious	-2,87	high_impact	4,2	neutral	0,78	damaging	0,15	deleterious	3,52	23,1	0,26	0,45	disease	0,74	disease	0,58	disease	0,7	disease	0,65	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	-0,13	high_impact	2,39	0,42	0,8	NA	NA	N	0,38	N	0,77	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5337	5337	C	T	MI.14589	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	868	290	L	F	Ctc/Ttc	-0,11	0,02	0	probably_damaging	1	neutral	0,38	neutral	-0,81	deleterious	-8,82	deleterious	-3,83	high_impact	4,2	neutral	0,94	damaging	0,15	deleterious	4,04	23,7	0,15	0,4	disease	0,89	disease	0,7	disease	0,7	disease	0,65	3	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,09	high_impact	2,39	0,37	0,8	NA	NA	N	0,45	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8373	8373	A	C	MI.1459	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	8	3	Q	P	cAa/cCa	7,3	1	0	probably_damaging	0,96	neutral	0,07	deleterious	-2,66	deleterious	-13,66	deleterious	-5,99	high_impact	3,9	neutral	0,88	damaging	0,06	deleterious	3,09	22,5	0,46398601	0,85	disease	0,83	neutral	0,21	neutral	0,44	neutral	0,25	5	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,81	low_impact	-2,07	medium_impact	-0,34	high_impact	2,25	0,34	0,85	23,53	8,05	P	0,6	P	0,9	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5337	5337	C	A	MI.14590	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	868	290	L	I	Ctc/Atc	-0,11	0,02	0	probably_damaging	1	neutral	0,22	neutral	-0,79	deleterious	-7,78	neutral	-1,92	high_impact	4,2	neutral	0,85	damaging	0,12	deleterious	4,34	24	0,27	0,45	disease	0,68	disease	0,61	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	-0,1	high_impact	2,39	0,37	0,8	NA	NA	N	0,41	N	0,85	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5338	5338	T	C	MI.14591	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	869	290	L	P	cTc/cCc	-0,11	0,02	0	probably_damaging	1	neutral	0,05	neutral	-0,82	deleterious	-12,3	deleterious	-6,7	high_impact	4,2	neutral	0,82	damaging	0,12	deleterious	3,97	23,6	0,03	0,35	disease	0,96	disease	0,75	disease	0,79	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	-0,5	high_impact	2,39	0,23	0,8	NA	NA	N	0,4	N	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5338	5338	T	A	MI.14592	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	869	290	L	H	cTc/cAc	-0,11	0,02	0	probably_damaging	1	neutral	0,12	neutral	-0,83	deleterious	-13,08	deleterious	-6,7	high_impact	4,2	neutral	0,84	damaging	0,12	deleterious	4,2	23,9	0,05	0,35	disease	0,96	disease	0,75	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,27	high_impact	2,39	0,21	0,8	NA	NA	N	0,42	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5338	5338	T	G	MI.14593	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	869	290	L	R	cTc/cGc	-0,11	0,02	0	probably_damaging	1	neutral	0,26	neutral	-0,82	deleterious	-12,11	deleterious	-5,75	high_impact	4,2	neutral	0,82	damaging	0,11	deleterious	4,29	24	0,02	0,35	disease	0,95	disease	0,86	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,88	low_impact	-3,54	medium_impact	-0,04	high_impact	2,39	0,13	0,8	NA	NA	N	0,42	N	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5340	5340	T	G	MI.14594	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	871	291	Y	D	Tac/Gac	-2,42	0	0	probably_damaging	0,97	neutral	0,06	neutral	1,6	deleterious	-6,19	deleterious	-8,86	medium_impact	3,38	neutral	0,84	neutral	0,33	deleterious	3,99	23,6	0,04	0,35	disease	0,82	disease	0,93	disease	0,76	disease	0,73	5	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,85	low_impact	-2,18	medium_impact	-0,46	medium_impact	1,7	0,2	0,8	NA	NA	N	0,43	N	0,97	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5340	5340	T	C	MI.14595	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	871	291	Y	H	Tac/Cac	-2,42	0	0	probably_damaging	0,97	neutral	0,17	neutral	1,6	deleterious	-5,52	deleterious	-4,6	medium_impact	3,38	neutral	0,88	neutral	0,41	deleterious	3,63	23,2	0,16	0,45	disease	0,87	disease	0,83	disease	0,72	disease	0,65	3	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,83	low_impact	-2,18	medium_impact	-0,17	medium_impact	1,7	0,29	0,8	NA	NA	N	0,42	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5340	5340	T	A	MI.14596	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	871	291	Y	N	Tac/Aac	-2,42	0	0	probably_damaging	0,97	neutral	0,15	neutral	1,61	deleterious	-5,28	deleterious	-8,08	medium_impact	3,04	neutral	0,87	neutral	0,46	deleterious	4,07	23,7	0,08	0,35	neutral	0,49	disease	0,91	disease	0,67	disease	0,76	5	deleterious	0,98	neutral	0,09	deleterious	1	deleterious	0,79	low_impact	-2,18	medium_impact	-0,21	medium_impact	1,42	0,24	0,8	NA	NA	N	0,42	N	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5341	5341	A	C	MI.14597	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	872	291	Y	S	tAc/tCc	5,68	0,87	0	probably_damaging	0,95	neutral	0,34	neutral	1,64	deleterious	-3,32	deleterious	-7,9	medium_impact	3,38	neutral	0,84	neutral	0,46	deleterious	3,79	23,4	0,08	0,35	disease	0,51	disease	0,86	disease	0,67	disease	0,74	5	neutral	0,96	neutral	0,2	deleterious	1	deleterious	0,77	low_impact	-1,97	medium_impact	0,05	medium_impact	1,7	0,23	0,8	NA	NA	N	0,52	P	0,94	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5341	5341	A	G	MI.14598	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	872	291	Y	C	tAc/tGc	5,68	0,87	0	probably_damaging	0,98	neutral	0,07	neutral	1,61	deleterious	-5,36	deleterious	-7,89	medium_impact	3,38	neutral	0,9	neutral	0,35	deleterious	3,62	23,2	0,06	0,35	disease	0,89	disease	0,92	disease	0,68	disease	0,66	3	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,83	low_impact	-2,34	medium_impact	-0,42	medium_impact	1,7	0,13	0,8	NA	NA	P	0,61	P	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5341	5341	A	T	MI.14599	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	872	291	Y	F	tAc/tTc	5,68	0,87	0	benign	0,08	neutral	1	neutral	2,2	neutral	0,69	deleterious	-2,6	neutral_impact	-0,23	neutral	0,87	neutral	0,95	deleterious	0,82	9,57	0,27	0,45	neutral	0,46	neutral	0,16	neutral	0,44	neutral	0,23	5	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,25	medium_impact	0,17	high_impact	1,87	low_impact	-1,34	0,32	0,8	NA	NA	N	0,44	N	0,3	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8595	8595	C	A	MI.146	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	69	23	I	M	atC/atA	4,52	0,99	0,01	possibly_damaging	0,82	neutral	0,17	neutral	4,32	neutral	-1,04	neutral	-1,56	low_impact	0,82	neutral	0,88	neutral	0,37	deleterious	3,47	23	0,43	0,65	disease	0,74	neutral	0,41	disease	0,53	disease	0,67	3	neutral	0,91	neutral	0,18	neutral	-3	deleterious	0,65	low_impact	-1,38	medium_impact	-0,1	medium_impact	-0,4	0,7	0,9	19,03	10,37	N	0,5	N	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8373	8373	A	T	MI.1460	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	8	3	Q	L	cAa/cTa	7,3	1	0	probably_damaging	0,94	deleterious	0	deleterious	-2,66	deleterious	-13,62	deleterious	-6,98	high_impact	3,9	neutral	0,87	damaging	0,06	deleterious	3,64	23,2	0,36619744	0,85	disease	0,76	neutral	0,15	neutral	0,45	neutral	0,22	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,76	low_impact	-1,89	low_impact	-1,4	high_impact	2,25	0,28	0,85	23,53	8,05	P	0,6	P	0,94	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5343	5343	T	C	MI.14600	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	874	292	F	L	Ttc/Ctc	-3,11	0	0	probably_damaging	1	neutral	0,58	neutral	0	deleterious	-7,09	deleterious	-5,74	high_impact	3,62	neutral	0,67	damaging	0,06	deleterious	4,28	24	0,14	0,4	neutral	0,37	disease	0,83	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,72	low_impact	-3,54	medium_impact	0,29	medium_impact	1,9	0,35	0,8	NA	NA	N	0,33	N	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5343	5343	T	A	MI.14601	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	874	292	F	I	Ttc/Atc	-3,11	0	0	probably_damaging	1	neutral	0,31	neutral	-0,01	deleterious	-7,47	deleterious	-5,74	high_impact	4,17	neutral	0,61	damaging	0,06	deleterious	4,67	24,5	0,12	0,4	disease	0,57	disease	0,78	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,76	low_impact	-3,54	medium_impact	0,02	high_impact	2,37	0,37	0,8	NA	NA	N	0,36	N	0,93	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5343	5343	T	G	MI.14602	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	874	292	F	V	Ttc/Gtc	-3,11	0	0	probably_damaging	1	neutral	0,33	neutral	-0,01	deleterious	-7,65	deleterious	-6,7	medium_impact	3,48	damaging	0,59	damaging	0,06	deleterious	4,28	24	0,1	0,4	disease	0,66	disease	0,83	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,04	medium_impact	1,79	0,31	0,8	NA	NA	N	0,27	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5344	5344	T	A	MI.14603	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	875	292	F	Y	tTc/tAc	7,3	1	0	probably_damaging	1	neutral	0,77	neutral	0,19	deleterious	-4,22	deleterious	-2,87	medium_impact	3,2	neutral	0,61	damaging	0,06	deleterious	4,32	24	0,15	0,4	neutral	0,34	disease	0,74	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0,5	medium_impact	1,55	0,52	0,8	NA	NA	N	0,52	P	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5344	5344	T	C	MI.14604	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	875	292	F	S	tTc/tCc	7,3	1	0	probably_damaging	1	neutral	0,23	neutral	-0,03	deleterious	-9,62	deleterious	-7,66	high_impact	4,17	damaging	0,51	damaging	0,07	deleterious	4,32	24	0,05	0,35	disease	0,87	disease	0,83	disease	0,71	disease	0,66	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,08	high_impact	2,37	0,37	0,8	NA	NA	P	0,58	P	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5344	5344	T	G	MI.14605	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	875	292	F	C	tTc/tGc	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	-0,03	deleterious	-10,94	deleterious	-7,66	high_impact	4,17	neutral	0,61	damaging	0,05	deleterious	4,21	23,9	0,05	0,35	disease	0,93	disease	0,82	disease	0,74	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,16	high_impact	2,37	0,26	0,8	NA	NA	P	0,58	P	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5345	5345	C	G	MI.14606	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	876	292	F	L	ttC/ttG	7,3	1	0	probably_damaging	1	neutral	0,58	neutral	0	deleterious	-7,09	deleterious	-5,74	high_impact	3,62	neutral	0,67	damaging	0,06	deleterious	4,45	24,2	0,14	0,4	neutral	0,37	disease	0,83	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,72	low_impact	-3,54	medium_impact	0,29	medium_impact	1,9	0,35	0,8	NA	NA	N	0,51	P	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5345	5345	C	A	MI.14607	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	876	292	F	L	ttC/ttA	7,3	1	0	probably_damaging	1	neutral	0,58	neutral	0	deleterious	-7,09	deleterious	-5,74	high_impact	3,62	neutral	0,67	damaging	0,06	deleterious	4,7	24,6	0,14	0,4	neutral	0,37	disease	0,83	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,72	low_impact	-3,54	medium_impact	0,29	medium_impact	1,9	0,35	0,8	NA	NA	N	0,52	P	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5346	5346	T	G	MI.14608	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	877	293	Y	D	Tac/Gac	-4,5	0	0	probably_damaging	1	neutral	0,11	deleterious	-2,6	deleterious	-14,46	deleterious	-9,57	high_impact	4,2	neutral	0,72	damaging	0,05	deleterious	3,96	23,6	0,03	0,35	NA	NA	disease	0,9	disease	0,8	disease	0,72	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	-0,3	high_impact	2,39	0,15	0,8	NA	NA	N	0,41	N	0,96	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5346	5346	T	A	MI.14609	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	877	293	Y	N	Tac/Aac	-4,5	0	0	probably_damaging	1	neutral	0,2	deleterious	-2,6	deleterious	-14,02	deleterious	-8,62	high_impact	4,2	neutral	0,66	damaging	0,04	deleterious	4,05	23,7	0,04	0,35	NA	NA	disease	0,88	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,54	medium_impact	-0,13	high_impact	2,39	0,15	0,8	NA	NA	N	0,39	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8373	8373	A	G	MI.1461	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	8	3	Q	R	cAa/cGa	7,3	1	0	probably_damaging	0,94	deleterious	0	deleterious	-2,65	deleterious	-12,74	deleterious	-3,99	high_impact	3,9	neutral	0,83	damaging	0,07	deleterious	3,29	22,8	0,52918828	0,85	disease	0,64	neutral	0,13	neutral	0,48	neutral	0,23	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,75	low_impact	-1,89	low_impact	-1,4	high_impact	2,25	0,34	0,85	23,53	8,05	P	0,61	P	0,77	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5346	5346	T	C	MI.14610	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	877	293	Y	H	Tac/Cac	-4,5	0	0	probably_damaging	1	neutral	0,29	deleterious	-2,6	deleterious	-12,99	deleterious	-4,79	high_impact	4,2	neutral	0,69	damaging	0,04	deleterious	3,61	23,2	0,06	0,35	NA	NA	disease	0,84	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,9	low_impact	-3,54	medium_impact	-0,01	high_impact	2,39	0,22	0,8	NA	NA	N	0,41	N	0,99	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5347	5347	A	G	MI.14611	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	878	293	Y	C	tAc/tGc	4,52	1	0	probably_damaging	1	neutral	0,1	deleterious	-2,6	deleterious	-15,07	deleterious	-8,62	high_impact	3,85	neutral	0,7	damaging	0,04	deleterious	4,12	23,8	0,04	0,35	NA	NA	disease	0,88	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,88	low_impact	-3,54	medium_impact	-0,32	high_impact	2,1	0,2	0,8	NA	NA	N	0,5	N	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5347	5347	A	T	MI.14612	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	878	293	Y	F	tAc/tTc	4,52	1	0	probably_damaging	1	neutral	0,5	deleterious	-2,58	deleterious	-10,77	deleterious	-3,83	high_impact	4,2	neutral	0,75	damaging	0,04	deleterious	4,04	23,7	0,12	0,4	NA	NA	disease	0,86	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,88	low_impact	-3,54	medium_impact	0,21	high_impact	2,39	0,34	0,8	NA	NA	P	0,55	P	0,8	polymorphism	0,99	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5347	5347	A	C	MI.14613	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	878	293	Y	S	tAc/tCc	4,52	1	0	probably_damaging	1	neutral	0,49	deleterious	-2,6	deleterious	-13,86	deleterious	-8,62	high_impact	4,2	neutral	0,62	damaging	0,06	deleterious	4,27	24	0,04	0,35	NA	NA	disease	0,87	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,89	low_impact	-3,54	medium_impact	0,2	high_impact	2,39	0,14	0,8	NA	NA	N	0,5	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5349	5349	C	G	MI.14614	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	880	294	L	V	Cta/Gta	-4,5	0	0	benign	0,01	neutral	0,47	neutral	0,86	deleterious	-4,46	neutral	-0,94	medium_impact	2,12	neutral	0,9	neutral	0,66	neutral	1,43	12,94	0,19	0,45	neutral	0,34	disease	0,51	neutral	0,45	neutral	0,36	3	neutral	0,52	deleterious	0,73	neutral	-3	neutral	0,18	medium_impact	1,03	medium_impact	0,18	medium_impact	0,64	0,59	0,8	NA	NA	N	0,35	N	0,08	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5349	5349	C	A	MI.14615	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	880	294	L	M	Cta/Ata	-4,5	0	0	benign	0,04	neutral	0,28	neutral	0,99	deleterious	-3,07	neutral	1,71	neutral_impact	-0,44	neutral	0,9	neutral	0,88	neutral	-0,7	0,07	0,21	0,45	disease	0,5	neutral	0,1	neutral	0,36	neutral	0,24	5	neutral	0,7	deleterious	0,62	neutral	-6	neutral	0,2	medium_impact	0,47	medium_impact	-0,02	low_impact	-1,52	0,44	0,8	NA	NA	N	0,42	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5350	5350	T	G	MI.14616	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	881	294	L	R	cTa/cGa	0,13	0	0	possibly_damaging	0,68	neutral	0,47	neutral	0,78	deleterious	-8,36	deleterious	-3,19	medium_impact	2,67	neutral	0,83	neutral	0,45	deleterious	2,61	20,3	0,02	0,35	disease	0,87	disease	0,85	disease	0,72	disease	0,63	3	neutral	0,67	neutral	0,4	NA	0	deleterious	0,78	low_impact	-1,1	medium_impact	0,18	medium_impact	1,1	0,19	0,8	NA	NA	N	0,3	N	0,48	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5350	5350	T	A	MI.14617	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	881	294	L	Q	cTa/cAa	0,13	0	0	possibly_damaging	0,75	neutral	0,19	neutral	0,78	deleterious	-8,41	neutral	-2,47	medium_impact	2,67	neutral	0,84	neutral	0,53	deleterious	2,5	19,44	0,02	0,35	disease	0,88	disease	0,71	disease	0,62	disease	0,63	3	neutral	0,86	neutral	0,22	NA	0	deleterious	0,75	low_impact	-1,23	medium_impact	-0,14	medium_impact	1,1	0,41	0,8	NA	NA	N	0,38	N	0,47	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5350	5350	T	C	MI.14618	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	881	294	L	P	cTa/cCa	0,13	0	0	possibly_damaging	0,75	neutral	0,14	neutral	0,78	deleterious	-8,81	deleterious	-3,98	medium_impact	2,67	neutral	0,78	neutral	0,43	deleterious	2,36	18,59	0,02	0,35	disease	0,9	disease	0,82	disease	0,73	disease	0,64	3	neutral	0,9	neutral	0,2	NA	0	deleterious	0,8	low_impact	-1,23	medium_impact	-0,23	medium_impact	1,1	0,36	0,8	NA	NA	N	0,32	N	0,81	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5352	5352	C	G	MI.14619	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	883	295	R	G	Cgc/Ggc	-2,88	0	0	probably_damaging	1	neutral	0,33	neutral	-0,7	deleterious	-10,18	deleterious	-6,7	high_impact	3,85	damaging	0,55	damaging	0,04	deleterious	4,29	24	0,03	0,35	disease	0,75	disease	0,79	disease	0,79	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,04	high_impact	2,1	0,2	0,8	NA	NA	N	0,34	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8374	8374	A	T	MI.1462	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	9	3	Q	H	caA/caT	6,84	1	0	probably_damaging	0,99	deleterious	0,03	deleterious	-2,66	deleterious	-14,21	deleterious	-4,99	high_impact	3,9	neutral	0,87	damaging	0,07	deleterious	3,42	23	0,46889253	0,85	disease	0,83	neutral	0,13	neutral	0,5	neutral	0,23	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,81	low_impact	-2,65	medium_impact	-0,56	high_impact	2,25	0,52	0,85	23,53	8,05	P	0,61	P	0,82	disease_causing	0,98	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5352	5352	C	A	MI.14620	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	883	295	R	S	Cgc/Agc	-2,88	0	0	probably_damaging	1	neutral	0,43	neutral	-0,7	deleterious	-9,61	deleterious	-5,74	high_impact	4,19	damaging	0,42	damaging	0,03	deleterious	4,65	24,5	0,03	0,35	disease	0,72	disease	0,81	disease	0,77	disease	0,7	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	0,14	high_impact	2,38	0,23	0,8	NA	NA	N	0,43	N	0,81	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5352	5352	C	T	MI.14621	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	883	295	R	C	Cgc/Tgc	-2,88	0	0	probably_damaging	1	neutral	0,18	neutral	-0,71	deleterious	-12,38	deleterious	-7,66	high_impact	4,19	damaging	0,53	damaging	0,02	deleterious	5,08	25,3	0,06	0,35	disease	0,8	disease	0,84	disease	0,81	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,16	high_impact	2,38	0,63	0,8	NA	NA	N	0,36	N	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5353	5353	G	C	MI.14622	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	884	295	R	P	cGc/cCc	4,29	1	0	probably_damaging	1	neutral	0,21	neutral	-0,7	deleterious	-10,69	deleterious	-6,7	high_impact	4,19	damaging	0,57	damaging	0,03	deleterious	4,33	24	0,02	0,35	disease	0,87	disease	0,85	disease	0,87	disease	0,64	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	-0,11	high_impact	2,38	0,11	0,8	NA	NA	P	0,56	P	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5353	5353	G	T	MI.14623	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	884	295	R	L	cGc/cTc	4,29	1	0	probably_damaging	1	neutral	0,69	neutral	-0,7	deleterious	-9,87	deleterious	-6,7	high_impact	4,19	damaging	0,49	damaging	0,03	deleterious	4,38	24,1	0,04	0,35	neutral	0,44	disease	0,93	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,4	high_impact	2,38	0,12	0,8	NA	NA	P	0,55	P	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5353	5353	G	A	MI.14624	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	884	295	R	H	cGc/cAc	4,29	1	0	probably_damaging	1	neutral	0,54	neutral	-0,68	deleterious	-8,27	deleterious	-4,79	high_impact	4,19	damaging	0,53	damaging	0,03	deleterious	4,6	24,4	0,09	0,35	disease	0,86	disease	0,81	disease	0,76	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0,25	high_impact	2,38	0,65	0,8	NA	NA	P	0,59	P	1	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5355	5355	C	A	MI.14625	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	886	296	L	M	Cta/Ata	-4,04	0	0	probably_damaging	1	neutral	0,27	neutral	1,32	deleterious	-3,56	neutral	-1,86	medium_impact	2,75	neutral	0,89	damaging	0,22	deleterious	3,78	23,4	0,22	0,45	disease	0,69	neutral	0,42	neutral	0,33	disease	0,56	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	-0,03	medium_impact	1,17	0,52	0,8	NA	NA	N	0,42	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5355	5355	C	G	MI.14626	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	886	296	L	V	Cta/Gta	-4,04	0	0	probably_damaging	1	neutral	0,38	neutral	1,37	neutral	-2,87	deleterious	-2,65	medium_impact	3,31	neutral	0,95	damaging	0,17	deleterious	3,44	23	0,17	0,45	neutral	0,34	neutral	0,47	disease	0,52	neutral	0,42	2	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,7	low_impact	-3,54	medium_impact	0,09	medium_impact	1,64	0,56	0,8	NA	NA	N	0,38	N	0,54	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5356	5356	T	C	MI.14627	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	887	296	L	P	cTa/cCa	-1,03	0	0	probably_damaging	1	neutral	0,18	neutral	1,24	deleterious	-7,44	deleterious	-6,59	high_impact	4,11	neutral	0,9	damaging	0,12	deleterious	4	23,6	0,02	0,35	disease	0,93	disease	0,76	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	-0,16	high_impact	2,32	0,35	0,8	NA	NA	N	0,45	N	0,9	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5356	5356	T	G	MI.14628	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	887	296	L	R	cTa/cGa	-1,03	0	0	probably_damaging	1	neutral	0,21	neutral	1,25	deleterious	-6,95	deleterious	-5,68	high_impact	4,11	neutral	0,87	damaging	0,12	deleterious	4,25	23,9	0,02	0,35	disease	0,91	disease	0,83	disease	0,75	disease	0,64	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	-0,11	high_impact	2,32	0,16	0,8	NA	NA	N	0,41	N	0,94	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5356	5356	T	A	MI.14629	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	887	296	L	Q	cTa/cAa	-1,03	0	0	probably_damaging	1	neutral	0,17	neutral	1,25	deleterious	-7,07	deleterious	-5,68	high_impact	4,11	neutral	0,9	damaging	0,13	deleterious	4,18	23,8	0,03	0,35	disease	0,92	disease	0,71	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,17	high_impact	2,32	0,31	0,8	NA	NA	N	0,43	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8374	8374	A	C	MI.1463	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	9	3	Q	H	caA/caC	6,84	1	0	probably_damaging	0,99	deleterious	0,03	deleterious	-2,66	deleterious	-14,21	deleterious	-4,99	high_impact	3,9	neutral	0,87	damaging	0,07	deleterious	3,28	22,8	0,46889253	0,85	disease	0,83	neutral	0,13	neutral	0,5	neutral	0,23	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,81	low_impact	-2,65	medium_impact	-0,56	high_impact	2,25	0,52	0,85	23,53	8,05	P	0,61	P	0,82	disease_causing	0,98	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5358	5358	A	C	MI.14630	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	889	297	I	L	Atc/Ctc	-2,88	0	0	benign	0,18	neutral	0,64	neutral	1,97	neutral	-0,42	neutral	-0,8	low_impact	1,58	neutral	0,89	neutral	0,48	deleterious	3,81	23,4	0,18	0,45	disease	0,5	neutral	0,49	neutral	0,39	neutral	0,37	3	neutral	0,24	deleterious	0,73	neutral	-6	neutral	0,36	medium_impact	-0,19	medium_impact	0,35	medium_impact	0,19	0,59	0,8	NA	NA	N	0,28	N	0,63	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5358	5358	A	T	MI.14631	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	889	297	I	F	Atc/Ttc	-2,88	0	0	possibly_damaging	0,66	neutral	0,68	neutral	1,93	neutral	-1,43	neutral	-2,12	low_impact	1,24	neutral	0,88	neutral	0,53	deleterious	3,86	23,5	0,13	0,4	disease	0,61	disease	0,59	disease	0,58	disease	0,67	3	neutral	0,59	deleterious	0,51	neutral	-3	deleterious	0,7	low_impact	-1,06	medium_impact	0,39	medium_impact	-0,1	0,6	0,8	NA	NA	N	0,23	N	0,71	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5358	5358	A	G	MI.14632	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	889	297	I	V	Atc/Gtc	-2,88	0	0	benign	0,02	neutral	0,48	neutral	2	neutral	0,01	neutral	0,14	low_impact	1,24	neutral	0,96	neutral	0,92	neutral	1,77	14,84	0,25	0,45	disease	0,54	neutral	0,23	neutral	0,22	neutral	0,49	0	neutral	0,5	deleterious	0,73	neutral	-6	neutral	0,16	medium_impact	0,75	medium_impact	0,19	medium_impact	-0,1	0,34	0,8	NA	NA	N	0,41	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5359	5359	T	A	MI.14633	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	890	297	I	N	aTc/aAc	-0,11	0	0	possibly_damaging	0,66	neutral	0,31	neutral	1,9	deleterious	-3,24	neutral	-2,4	low_impact	1,58	neutral	0,85	neutral	0,47	deleterious	4,71	24,6	0,06	0,35	disease	0,74	disease	0,71	disease	0,51	disease	0,5	0	neutral	0,74	neutral	0,33	neutral	-3	deleterious	0,73	low_impact	-1,06	medium_impact	0,02	medium_impact	0,19	0,29	0,8	NA	NA	N	0,31	N	0,91	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5359	5359	T	C	MI.14634	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	890	297	I	T	aTc/aCc	-0,11	0	0	benign	0,02	neutral	0,4	neutral	2,13	neutral	1,15	neutral	0,61	neutral_impact	-1,86	neutral	0,98	neutral	0,97	neutral	1,08	11,1	0,1	0,4	neutral	0,49	neutral	0,12	neutral	0,25	neutral	0,25	5	neutral	0,59	deleterious	0,69	neutral	-6	neutral	0,14	medium_impact	0,75	medium_impact	0,11	low_impact	-2,71	0,37	0,8	NA	NA	N	0,45	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5359	5359	T	G	MI.14635	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	890	297	I	S	aTc/aGc	-0,11	0	0	benign	0,37	neutral	0,41	neutral	2,28	neutral	1,94	neutral	-1,17	neutral_impact	-0,57	neutral	0,81	neutral	0,95	deleterious	3,1	22,5	0,05	0,35	neutral	0,48	neutral	0,33	neutral	0,29	neutral	0,43	2	neutral	0,52	deleterious	0,52	neutral	-6	deleterious	0,48	medium_impact	-0,59	medium_impact	0,12	low_impact	-1,62	0,39	0,8	NA	NA	N	0,35	N	0,77	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5360	5360	C	G	MI.14636	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	891	297	I	M	atC/atG	-0,11	0	0	possibly_damaging	0,86	neutral	0,23	neutral	1,94	neutral	-1,2	neutral	-1,07	neutral_impact	0,78	neutral	0,93	neutral	0,88	deleterious	2,33	18,36	0,2	0,45	disease	0,51	neutral	0,33	neutral	0,28	neutral	0,35	3	neutral	0,9	neutral	0,19	neutral	-3	deleterious	0,66	low_impact	-1,52	medium_impact	-0,08	medium_impact	-0,49	0,7	0,85	NA	NA	N	0,52	P	0,69	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5360	5360	C	A	MI.14637	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	891	297	I	M	atC/atA	-0,11	0	0	possibly_damaging	0,86	neutral	0,23	neutral	1,94	neutral	-1,2	neutral	-1,07	neutral_impact	0,78	neutral	0,93	neutral	0,88	deleterious	2,76	21,1	0,2	0,45	disease	0,51	neutral	0,33	neutral	0,28	neutral	0,35	3	neutral	0,9	neutral	0,19	neutral	-3	deleterious	0,66	low_impact	-1,52	medium_impact	-0,08	medium_impact	-0,49	0,7	0,85	NA	NA	N	0,52	P	0,69	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5361	5361	T	G	MI.14638	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	892	298	Y	D	Tac/Gac	-4,04	0	0	probably_damaging	1	neutral	0,11	neutral	0,25	deleterious	-10,93	deleterious	-9,56	high_impact	4,18	neutral	0,71	damaging	0,07	deleterious	4,01	23,6	0,03	0,35	disease	0,91	disease	0,89	disease	0,82	disease	0,64	3	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,3	high_impact	2,37	0,15	0,8	NA	NA	N	0,39	N	0,96	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5361	5361	T	C	MI.14639	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	892	298	Y	H	Tac/Cac	-4,04	0	0	probably_damaging	1	neutral	0,3	neutral	0,29	deleterious	-6,43	deleterious	-4,78	medium_impact	3,48	neutral	0,78	damaging	0,15	deleterious	3,63	23,2	0,17	0,45	disease	0,87	disease	0,81	disease	0,77	disease	0,5	0	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	0	medium_impact	1,79	0,2	0,8	NA	NA	N	0,35	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8375	8375	C	A	MI.1464	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	10	4	L	M	Cta/Ata	-0,1	0	0	probably_damaging	1	neutral	0,24	neutral	-0,1	deleterious	-4,98	neutral	-1,99	high_impact	3,9	neutral	1	neutral	0,43	deleterious	3,77	23,4	0,35482158	0,85	disease	0,54	neutral	0,11	disease	0,61	neutral	0,19	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,01	high_impact	2,25	0,63	0,85	25	8,38	P	0,59	P	0,61	polymorphism	0,99	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5361	5361	T	A	MI.14640	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	892	298	Y	N	Tac/Aac	-4,04	0	0	probably_damaging	1	neutral	0,22	neutral	0,25	deleterious	-9,7	deleterious	-8,61	high_impact	3,83	neutral	0,77	damaging	0,06	deleterious	4,07	23,7	0,08	0,35	disease	0,85	disease	0,87	disease	0,73	disease	0,63	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	-0,1	high_impact	2,08	0,23	0,8	NA	NA	N	0,34	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5362	5362	A	C	MI.14641	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	893	298	Y	S	tAc/tCc	4,52	1	0	probably_damaging	1	neutral	0,3	neutral	0,27	deleterious	-7,37	deleterious	-8,61	high_impact	3,83	neutral	0,73	damaging	0,08	deleterious	3,79	23,4	0,06	0,35	disease	0,73	disease	0,86	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	0	high_impact	2,08	0,22	0,8	NA	NA	P	0,56	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5362	5362	A	G	MI.14642	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	893	298	Y	C	tAc/tGc	4,52	1	0	probably_damaging	1	neutral	0,11	neutral	0,25	deleterious	-11,02	deleterious	-8,61	high_impact	4,18	neutral	0,73	damaging	0,06	deleterious	3,63	23,2	0,05	0,35	disease	0,54	disease	0,87	disease	0,8	disease	0,72	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	-0,3	high_impact	2,37	0,1	0,8	NA	NA	P	0,55	P	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5362	5362	A	T	MI.14643	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	893	298	Y	F	tAc/tTc	4,52	1	0	probably_damaging	1	neutral	0,51	neutral	0,55	deleterious	-3,35	deleterious	-3,83	medium_impact	3,48	neutral	0,83	damaging	0,12	deleterious	3,54	23,1	0,24	0,45	neutral	0,45	disease	0,84	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,22	medium_impact	1,79	0,41	0,8	NA	NA	N	0,49	N	0,8	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5364	5364	T	C	MI.14644	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	895	299	S	P	Tcc/Ccc	-1,96	0	0	possibly_damaging	0,46	neutral	0,21	neutral	1,75	deleterious	-3,85	deleterious	-4,01	medium_impact	2,81	neutral	0,86	neutral	0,38	deleterious	2,58	19,95	0,04	0,35	disease	0,9	disease	0,82	disease	0,65	disease	0,66	3	neutral	0,76	neutral	0,38	NA	0	deleterious	0,73	medium_impact	-0,73	medium_impact	-0,11	medium_impact	1,22	0,35	0,8	NA	NA	N	0,33	N	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5364	5364	T	G	MI.14645	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	895	299	S	A	Tcc/Gcc	-1,96	0	0	benign	0	neutral	0,52	neutral	1,93	neutral	-0,45	neutral	-1,84	neutral_impact	0,02	neutral	0,93	neutral	0,99	deleterious	0,14	4,06	0,25	0,45	neutral	0,41	neutral	0,11	neutral	0,24	neutral	0,25	5	neutral	0,47	deleterious	0,76	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,23	low_impact	-1,13	0,49	0,8	NA	NA	N	0,43	N	0,09	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5364	5364	T	A	MI.14646	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	895	299	S	T	Tcc/Acc	-1,96	0	0	benign	0,01	neutral	0,4	neutral	1,94	neutral	-0,38	neutral	-1,82	neutral_impact	0,56	neutral	0,97	neutral	0,98	deleterious	0,67	8,62	0,24	0,45	disease	0,7	neutral	0,14	neutral	0,23	neutral	0,37	3	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,18	medium_impact	1,03	medium_impact	0,11	medium_impact	-0,67	0,59	0,8	NA	NA	N	0,45	N	0,1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5365	5365	C	A	MI.14647	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	896	299	S	Y	tCc/tAc	-0,57	0	0	possibly_damaging	0,73	neutral	1	neutral	1,76	deleterious	-3,29	deleterious	-4,9	low_impact	1,36	neutral	0,87	neutral	0,74	deleterious	3,99	23,6	0,05	0,35	disease	0,84	neutral	0,45	neutral	0,38	disease	0,63	3	neutral	0,73	deleterious	0,64	neutral	-3	deleterious	0,71	low_impact	-1,19	high_impact	1,87	medium_impact	0	0,29	0,8	NA	NA	N	0,28	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5365	5365	C	G	MI.14648	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	896	299	S	C	tCc/tGc	-0,57	0	0	possibly_damaging	0,79	neutral	0,18	neutral	1,74	deleterious	-4,24	deleterious	-3,86	neutral_impact	0,77	neutral	0,83	neutral	0,63	deleterious	3,51	23,1	0,08	0,35	disease	0,85	neutral	0,34	neutral	0,33	disease	0,65	3	neutral	0,89	neutral	0,2	neutral	-3	deleterious	0,7	low_impact	-1,32	medium_impact	-0,16	medium_impact	-0,5	0,34	0,8	NA	NA	N	0,39	N	0,52	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5365	5365	C	T	MI.14649	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	896	299	S	F	tCc/tTc	-0,57	0	0	possibly_damaging	0,5	neutral	0,71	neutral	1,77	neutral	-2,74	deleterious	-4,89	medium_impact	2,81	neutral	0,89	neutral	0,47	deleterious	3,98	23,6	0,05	0,35	disease	0,76	disease	0,69	neutral	0,42	neutral	0,47	1	neutral	0,41	deleterious	0,61	NA	0	deleterious	0,68	medium_impact	-0,8	medium_impact	0,42	medium_impact	1,22	0,14	0,8	NA	NA	N	0,31	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8375	8375	C	G	MI.1465	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	10	4	L	V	Cta/Gta	-0,1	0	0	probably_damaging	0,97	neutral	0,05	neutral	-0,24	deleterious	-7,49	deleterious	-2,99	high_impact	3,9	neutral	1	neutral	0,5	deleterious	3,24	22,8	0,51005936	0,85	neutral	0,36	neutral	0,1	disease	0,64	neutral	0,19	6	deleterious	0,99	neutral	0,04	deleterious	2	deleterious	0,73	low_impact	-2,19	medium_impact	-0,43	high_impact	2,25	0,5	0,85	25	8,38	P	0,62	P	0,46	polymorphism	0,98	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5367	5367	A	C	MI.14650	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	898	300	T	P	Acc/Ccc	-7,28	0	0	possibly_damaging	0,9	neutral	0,2	neutral	1,72	deleterious	-5,01	deleterious	-4,99	high_impact	3,56	neutral	0,8	neutral	0,31	deleterious	4,1	23,7	0,04	0,35	disease	0,79	disease	0,83	disease	0,73	disease	0,72	4	neutral	0,94	neutral	0,15	deleterious	1	deleterious	0,83	low_impact	-1,67	medium_impact	-0,13	medium_impact	1,85	0,45	0,8	NA	NA	N	0,33	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5367	5367	A	G	MI.14651	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	898	300	T	A	Acc/Gcc	-7,28	0	0	benign	0,34	neutral	0,5	neutral	1,97	neutral	-0,2	deleterious	-3,84	low_impact	1,56	neutral	0,87	neutral	0,72	deleterious	4,05	23,7	0,25	0,45	neutral	0,49	neutral	0,21	neutral	0,36	neutral	0,33	3	neutral	0,42	deleterious	0,58	neutral	-6	deleterious	0,46	medium_impact	-0,53	medium_impact	0,21	medium_impact	0,17	0,45	0,8	NA	NA	N	0,35	N	0,83	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5367	5367	A	T	MI.14652	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	898	300	T	S	Acc/Tcc	-7,28	0	0	possibly_damaging	0,69	neutral	0,42	neutral	1,87	neutral	-0,92	deleterious	-2,7	low_impact	1,6	neutral	0,83	neutral	0,92	deleterious	2,33	18,34	0,3	0,45	neutral	0,48	neutral	0,17	neutral	0,3	neutral	0,28	4	neutral	0,7	neutral	0,37	neutral	-3	deleterious	0,62	low_impact	-1,12	medium_impact	0,13	medium_impact	0,2	0,69	0,85	NA	NA	N	0,36	N	0,35	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5368	5368	C	T	MI.14653	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	899	300	T	I	aCc/aTc	-0,8	0	0	benign	0,02	neutral	0,4	neutral	1,82	neutral	-1,56	deleterious	-4,82	medium_impact	2,36	neutral	0,86	neutral	0,58	deleterious	4,05	23,7	0,11	0,4	neutral	0,4	disease	0,58	neutral	0,38	neutral	0,21	6	neutral	0,58	deleterious	0,69	neutral	-3	neutral	0,19	medium_impact	0,75	medium_impact	0,11	medium_impact	0,84	0,62	0,8	NA	NA	N	0,38	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5368	5368	C	A	MI.14654	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	899	300	T	N	aCc/aAc	-0,8	0	0	possibly_damaging	0,9	neutral	0,31	neutral	1,72	deleterious	-4,7	deleterious	-3,94	high_impact	3,56	neutral	0,85	neutral	0,46	deleterious	3,83	23,4	0,26	0,45	disease	0,79	disease	0,68	disease	0,63	disease	0,7	4	neutral	0,92	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-1,67	medium_impact	0,02	medium_impact	1,85	0,6	0,8	NA	NA	N	0,37	N	0,84	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5368	5368	C	G	MI.14655	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	899	300	T	S	aCc/aGc	-0,8	0	0	possibly_damaging	0,69	neutral	0,42	neutral	1,87	neutral	-0,92	deleterious	-2,7	low_impact	1,6	neutral	0,83	neutral	0,92	deleterious	2,03	16,41	0,3	0,45	neutral	0,48	neutral	0,17	neutral	0,3	neutral	0,28	4	neutral	0,7	neutral	0,37	neutral	-3	deleterious	0,62	low_impact	-1,12	medium_impact	0,13	medium_impact	0,2	0,69	0,85	NA	NA	N	0,37	N	0,35	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5370	5370	T	C	MI.14656	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	901	301	S	P	Tca/Cca	-3,11	0	0	probably_damaging	1	neutral	0,2	neutral	1,82	deleterious	-4,35	deleterious	-4,01	medium_impact	2,68	neutral	0,74	neutral	0,33	deleterious	4,12	23,8	0,06	0,35	disease	0,84	disease	0,87	disease	0,79	disease	0,77	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,9	low_impact	-3,54	medium_impact	-0,13	medium_impact	1,11	0,18	0,8	NA	NA	N	0,33	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5370	5370	T	G	MI.14657	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	901	301	S	A	Tca/Gca	-3,11	0	0	probably_damaging	1	neutral	0,51	neutral	1,98	neutral	-0,13	neutral	-1,72	neutral_impact	0,36	neutral	0,9	neutral	0,98	deleterious	2,25	17,81	0,36	0,5	neutral	0,46	neutral	0,22	neutral	0,37	neutral	0,4	2	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	0,22	medium_impact	-0,84	0,36	0,8	NA	NA	N	0,38	N	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5370	5370	T	A	MI.14658	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	901	301	S	T	Tca/Aca	-3,11	0	0	probably_damaging	1	neutral	0,4	neutral	2,17	neutral	1,02	neutral	-1,87	neutral_impact	-0,12	neutral	0,9	neutral	0,98	deleterious	1,9	15,59	0,33	0,5	disease	0,55	neutral	0,06	neutral	0,26	neutral	0,28	4	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,11	low_impact	-1,25	0,35	0,8	NA	NA	N	0,47	N	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5371	5371	C	G	MI.14659	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	902	301	S	W	tCa/tGa	-0,34	0	0	probably_damaging	1	neutral	0,18	neutral	1,81	deleterious	-5,05	deleterious	-5,79	medium_impact	3,02	neutral	0,9	neutral	0,4	deleterious	4,47	24,2	0,07	0,35	disease	0,89	disease	0,85	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,16	medium_impact	1,4	0,12	0,8	NA	NA	N	0,42	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8376	8376	T	C	MI.1466	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	11	4	L	P	cTa/cCa	-1,49	0	0	probably_damaging	1	deleterious	0,02	neutral	-0,27	deleterious	-11,28	deleterious	-6,97	high_impact	3,9	neutral	0,99	damaging	0,24	deleterious	3,85	23,4	0,23790843	0,85	disease	0,71	neutral	0,33	disease	0,62	neutral	0,24	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,6	medium_impact	-0,66	high_impact	2,25	0,39	0,85	25	8,38	N	0,52	P	0,97	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5371	5371	C	T	MI.14660	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	902	301	S	L	tCa/tTa	-0,34	0	0	probably_damaging	1	neutral	0,66	neutral	1,97	neutral	-0,29	deleterious	-4,69	medium_impact	2,68	neutral	0,88	neutral	0,49	deleterious	4,76	24,7	0,11	0,4	disease	0,65	disease	0,78	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,37	medium_impact	1,11	0,34	0,8	NA	NA	N	0,28	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5373	5373	A	C	MI.14661	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	904	302	I	L	Atc/Ctc	-1,26	0	0	benign	0	neutral	1	neutral	2,63	neutral	2,71	neutral	1,66	neutral_impact	-1,74	neutral	0,83	neutral	0,88	neutral	-0,68	0,08	0,25	0,45	neutral	0,36	neutral	0,16	neutral	0,22	neutral	0,27	5	neutral	0	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,95	high_impact	1,87	low_impact	-2,61	0,67	0,85	NA	NA	N	0,3	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5373	5373	A	G	MI.14662	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	904	302	I	V	Atc/Gtc	-1,26	0	0	benign	0,01	neutral	0,5	neutral	1,95	neutral	-0,58	neutral	-0,85	low_impact	1,66	neutral	0,9	neutral	0,74	neutral	1,35	12,52	0,48	0,55	neutral	0,49	neutral	0,39	disease	0,51	neutral	0,45	1	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,16	medium_impact	1,03	medium_impact	0,21	medium_impact	0,25	0,4	0,8	NA	NA	N	0,36	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5373	5373	A	T	MI.14663	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	904	302	I	F	Atc/Ttc	-1,26	0	0	benign	0,21	neutral	0,75	neutral	1,88	neutral	-2,53	neutral	-1,9	low_impact	1,51	neutral	0,86	neutral	0,49	deleterious	2,36	18,59	0,21	0,45	disease	0,68	disease	0,76	disease	0,53	disease	0,64	3	neutral	0,15	deleterious	0,77	neutral	-6	deleterious	0,52	medium_impact	-0,27	medium_impact	0,47	medium_impact	0,13	0,62	0,8	NA	NA	N	0,2	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5374	5374	T	C	MI.14664	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	905	302	I	T	aTc/aCc	0,13	0	0	benign	0,18	neutral	0,61	neutral	1,88	neutral	-2,25	deleterious	-2,84	medium_impact	2,21	neutral	0,87	neutral	0,49	deleterious	1,96	15,97	0,09	0,35	neutral	0,44	disease	0,63	disease	0,62	disease	0,69	4	neutral	0,27	deleterious	0,72	neutral	-3	neutral	0,39	medium_impact	-0,19	medium_impact	0,32	medium_impact	0,72	0,13	0,8	NA	NA	N	0,23	N	0,71	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5374	5374	T	G	MI.14665	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	905	302	I	S	aTc/aGc	0,13	0	0	benign	0,34	neutral	0,44	neutral	1,89	neutral	-1,97	deleterious	-3,71	low_impact	1,66	neutral	0,87	neutral	0,5	deleterious	2,83	21,5	0,03	0,35	neutral	0,34	disease	0,81	disease	0,64	disease	0,72	4	neutral	0,48	deleterious	0,55	neutral	-6	deleterious	0,52	medium_impact	-0,53	medium_impact	0,15	medium_impact	0,25	0,1	0,8	NA	NA	N	0,3	N	0,85	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5374	5374	T	A	MI.14666	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	905	302	I	N	aTc/aAc	0,13	0	0	possibly_damaging	0,66	neutral	0,37	neutral	1,86	deleterious	-3,87	deleterious	-4,67	medium_impact	2,21	neutral	0,88	neutral	0,46	deleterious	4,49	24,3	0,08	0,35	neutral	0,47	disease	0,81	disease	0,66	disease	0,73	5	neutral	0,7	neutral	0,36	NA	0	deleterious	0,69	low_impact	-1,06	medium_impact	0,08	medium_impact	0,72	0,1	0,8	NA	NA	N	0,34	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5375	5375	C	A	MI.14667	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	906	302	I	M	atC/atA	4,52	0,79	0	benign	0,01	neutral	0,3	neutral	2,16	neutral	1,15	neutral	0,26	neutral_impact	0,74	neutral	0,95	neutral	0,91	deleterious	0,81	9,53	0,33	0,5	disease	0,65	neutral	0,48	neutral	0,29	neutral	0,44	1	neutral	0,69	deleterious	0,65	neutral	-6	neutral	0,22	medium_impact	1,03	medium_impact	0	medium_impact	-0,52	0,58	0,8	NA	NA	N	0,38	N	0,56	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5375	5375	C	G	MI.14668	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	906	302	I	M	atC/atG	4,52	0,79	0	benign	0,01	neutral	0,3	neutral	2,16	neutral	1,15	neutral	0,26	neutral_impact	0,74	neutral	0,95	neutral	0,91	deleterious	0,39	6,53	0,33	0,5	disease	0,65	neutral	0,48	neutral	0,29	neutral	0,44	1	neutral	0,69	deleterious	0,65	neutral	-6	neutral	0,22	medium_impact	1,03	medium_impact	0	medium_impact	-0,52	0,58	0,8	NA	NA	N	0,38	N	0,56	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5376	5376	A	C	MI.14669	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	907	303	T	P	Aca/Cca	-8,2	0	0	probably_damaging	0,98	neutral	0,23	neutral	1,25	deleterious	-6,72	deleterious	-5,71	high_impact	3,83	neutral	0,77	damaging	0,1	deleterious	3,61	23,2	0,04	0,35	neutral	0,41	disease	0,77	disease	0,73	disease	0,68	4	deleterious	0,98	neutral	0,13	deleterious	2	deleterious	0,77	low_impact	-2,34	medium_impact	-0,08	high_impact	2,08	0,32	0,8	NA	NA	N	0,32	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8376	8376	T	G	MI.1467	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	11	4	L	R	cTa/cGa	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	-0,27	deleterious	-11,05	deleterious	-5,98	high_impact	3,9	neutral	1	neutral	0,29	deleterious	4,07	23,7	0,26016055	0,85	disease	0,77	neutral	0,36	disease	0,67	neutral	0,29	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,6	low_impact	-1,4	high_impact	2,25	0,3	0,85	25	8,38	N	0,53	P	0,96	disease_causing	0,56	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5376	5376	A	T	MI.14670	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	907	303	T	S	Aca/Tca	-8,2	0	0	benign	0,37	neutral	0,47	neutral	1,3	deleterious	-4,05	deleterious	-3,78	high_impact	4,17	neutral	0,88	damaging	0,27	deleterious	3,38	23	0,4	0,5	neutral	0,49	disease	0,68	disease	0,68	disease	0,65	3	neutral	0,46	deleterious	0,55	neutral	-2	deleterious	0,51	medium_impact	-0,59	medium_impact	0,18	high_impact	2,37	0,5	0,8	NA	NA	N	0,39	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5376	5376	A	G	MI.14671	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	907	303	T	A	Aca/Gca	-8,2	0	0	possibly_damaging	0,7	neutral	0,5	neutral	1,29	deleterious	-4,46	deleterious	-4,75	high_impact	4,17	neutral	0,82	damaging	0,13	deleterious	3,61	23,2	0,28	0,45	disease	0,54	disease	0,56	disease	0,65	disease	0,63	3	neutral	0,68	neutral	0,4	deleterious	1	deleterious	0,69	low_impact	-1,13	medium_impact	0,21	high_impact	2,37	0,37	0,8	NA	NA	N	0,35	N	0,69	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5377	5377	C	T	MI.14672	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	908	303	T	M	aCa/aTa	2,9	0,95	0	probably_damaging	0,99	neutral	0,36	neutral	1,31	deleterious	-3,94	deleterious	-5,71	high_impact	3,83	neutral	0,83	damaging	0,11	deleterious	4,18	23,8	0,14	0,4	disease	0,86	disease	0,77	disease	0,73	disease	0,67	3	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,8	low_impact	-2,62	medium_impact	0,07	high_impact	2,08	0,56	0,8	NA	NA	N	0,48	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5377	5377	C	A	MI.14673	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	908	303	T	K	aCa/aAa	2,9	0,95	0	possibly_damaging	0,9	neutral	0,42	neutral	1,26	deleterious	-6,13	deleterious	-5,71	high_impact	4,17	neutral	0,83	damaging	0,09	deleterious	4,56	24,4	0,09	0,35	disease	0,53	disease	0,83	disease	0,77	disease	0,71	4	neutral	0,9	neutral	0,26	deleterious	1	deleterious	0,8	low_impact	-1,67	medium_impact	0,13	high_impact	2,37	0,31	0,8	NA	NA	N	0,54	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5379	5379	C	G	MI.14674	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	910	304	L	V	Cta/Gta	-15,37	0	0	possibly_damaging	0,54	neutral	0,55	neutral	1,74	neutral	-2,2	neutral	-1,55	low_impact	1,77	neutral	0,88	neutral	0,65	deleterious	3,51	23,1	0,36	0,5	neutral	0,48	disease	0,52	neutral	0,23	neutral	0,37	3	neutral	0,5	deleterious	0,51	neutral	-3	deleterious	0,62	medium_impact	-0,86	medium_impact	0,26	medium_impact	0,35	0,33	0,8	NA	NA	N	0,28	N	0,3	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5379	5379	C	A	MI.14675	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	910	304	L	M	Cta/Ata	-15,37	0	0	benign	0,15	neutral	0,29	neutral	1,82	neutral	-1,16	neutral	1,11	neutral_impact	0,05	neutral	0,89	neutral	0,87	neutral	1,17	11,58	0,31	0,45	neutral	0,47	neutral	0,13	neutral	0,13	neutral	0,28	4	neutral	0,66	deleterious	0,57	neutral	-6	neutral	0,38	medium_impact	-0,11	medium_impact	-0,01	low_impact	-1,1	0,46	0,8	NA	NA	N	0,56	P	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5380	5380	T	G	MI.14676	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	911	304	L	R	cTa/cGa	-0,11	0	0	probably_damaging	0,95	neutral	0,38	neutral	1,67	deleterious	-4,62	deleterious	-3,76	medium_impact	3,1	neutral	0,77	neutral	0,4	deleterious	4,28	24	0,09	0,35	disease	0,56	disease	0,85	disease	0,62	disease	0,72	4	neutral	0,95	neutral	0,22	deleterious	1	deleterious	0,84	low_impact	-1,97	medium_impact	0,09	medium_impact	1,47	0,12	0,8	NA	NA	N	0,28	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5380	5380	T	A	MI.14677	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	911	304	L	Q	cTa/cAa	-0,11	0	0	probably_damaging	0,95	neutral	0,31	neutral	1,67	deleterious	-4,77	deleterious	-3,17	medium_impact	2,55	neutral	0,82	neutral	0,52	deleterious	4,35	24,1	0,1	0,4	neutral	0,37	disease	0,75	neutral	0,28	disease	0,51	0	neutral	0,96	neutral	0,18	deleterious	1	deleterious	0,76	low_impact	-1,97	medium_impact	0,02	medium_impact	1	0,12	0,8	NA	NA	N	0,34	N	0,81	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5380	5380	T	C	MI.14678	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	911	304	L	P	cTa/cCa	-0,11	0	0	probably_damaging	0,97	neutral	0,24	neutral	1,66	deleterious	-5,2	deleterious	-4,68	medium_impact	2,75	neutral	0,7	neutral	0,34	deleterious	4,07	23,7	0,05	0,35	disease	0,79	disease	0,85	disease	0,54	disease	0,69	4	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,88	low_impact	-2,18	medium_impact	-0,07	medium_impact	1,17	0,16	0,8	NA	NA	N	0,3	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5382	5382	C	G	MI.14679	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	913	305	L	V	Ctc/Gtc	-1,96	0	0	possibly_damaging	0,56	neutral	0,51	neutral	1,99	neutral	-0,2	neutral	-1,21	neutral_impact	0	neutral	0,88	neutral	0,7	deleterious	1,9	15,56	0,36	0,5	disease	0,64	neutral	0,33	neutral	0,3	disease	0,6	2	neutral	0,54	deleterious	0,48	neutral	-3	deleterious	0,62	medium_impact	-0,89	medium_impact	0,22	low_impact	-1,14	0,29	0,8	NA	NA	N	0,35	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8376	8376	T	A	MI.1468	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	11	4	L	Q	cTa/cAa	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	-0,27	deleterious	-10,71	deleterious	-5,98	high_impact	3,9	neutral	1	neutral	0,35	deleterious	4,09	23,7	0,24042424	0,85	disease	0,78	neutral	0,33	disease	0,64	neutral	0,24	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,6	low_impact	-1,4	high_impact	2,25	0,46	0,85	25	8,38	P	0,55	P	0,91	disease_causing	0,5	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5382	5382	C	T	MI.14680	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	913	305	L	F	Ctc/Ttc	-1,96	0	0	benign	0,04	neutral	0,74	neutral	2,09	neutral	1,29	neutral	4,46	neutral_impact	-3,15	neutral	0,91	neutral	0,91	neutral	-0,53	0,19	0,38	0,5	disease	0,63	neutral	0,13	neutral	0,14	neutral	0,37	3	neutral	0,19	deleterious	0,85	neutral	-6	neutral	0,23	medium_impact	0,47	medium_impact	0,46	low_impact	-3,8	0,38	0,8	NA	NA	N	0,33	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5382	5382	C	A	MI.14681	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	913	305	L	I	Ctc/Atc	-1,96	0	0	possibly_damaging	0,56	neutral	0,4	neutral	1,99	neutral	-0,22	neutral	-0,25	neutral_impact	0	neutral	0,88	neutral	0,56	deleterious	2,57	19,91	0,35	0,5	disease	0,71	neutral	0,32	neutral	0,29	disease	0,64	3	neutral	0,62	neutral	0,42	neutral	-3	deleterious	0,61	medium_impact	-0,89	medium_impact	0,11	low_impact	-1,14	0,41	0,8	NA	NA	N	0,41	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5383	5383	T	A	MI.14682	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	914	305	L	H	cTc/cAc	0,59	0,09	0	probably_damaging	0,97	neutral	0,54	neutral	1,97	neutral	-0,82	neutral	-1,72	neutral_impact	-0,55	neutral	0,84	neutral	0,65	deleterious	4,35	24,1	0,12	0,4	disease	0,85	neutral	0,46	neutral	0,23	disease	0,65	3	neutral	0,96	neutral	0,29	neutral	-2	deleterious	0,81	low_impact	-2,18	medium_impact	0,25	low_impact	-1,61	0,13	0,8	NA	NA	N	0,28	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5383	5383	T	C	MI.14683	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	914	305	L	P	cTc/cCc	0,59	0,09	0	probably_damaging	0,95	neutral	0,25	neutral	2,16	neutral	1,88	deleterious	-4,18	neutral_impact	-2,42	neutral	0,86	neutral	0,85	deleterious	2,97	22,1	0,1	0,4	disease	0,83	neutral	0,17	neutral	0,25	disease	0,55	1	neutral	0,96	neutral	0,15	neutral	-2	deleterious	0,78	low_impact	-1,97	medium_impact	-0,06	low_impact	-3,18	0,18	0,8	NA	NA	N	0,38	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5383	5383	T	G	MI.14684	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	914	305	L	R	cTc/cGc	0,59	0,09	0	probably_damaging	0,93	neutral	0,35	neutral	1,95	neutral	-1,75	deleterious	-3,24	neutral_impact	0	neutral	0,81	neutral	0,48	deleterious	4,26	23,9	0,09	0,35	disease	0,89	disease	0,77	neutral	0,45	disease	0,67	3	neutral	0,93	neutral	0,21	neutral	-2	deleterious	0,88	low_impact	-1,83	medium_impact	0,06	low_impact	-1,14	0,15	0,8	NA	NA	N	0,32	N	0,75	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5385	5385	C	A	MI.14685	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	916	306	P	T	Ccc/Acc	-7,74	0	0	probably_damaging	1	neutral	0,41	neutral	1,07	deleterious	-4,42	deleterious	-7,65	high_impact	4,18	neutral	0,7	damaging	0,05	deleterious	3,83	23,4	0,44	0,55	disease	0,53	disease	0,85	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,12	high_impact	2,37	0,56	0,8	NA	NA	N	0,34	N	0,88	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5385	5385	C	G	MI.14686	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	916	306	P	A	Ccc/Gcc	-7,74	0	0	probably_damaging	1	neutral	0,51	neutral	1,05	deleterious	-4,9	deleterious	-7,65	high_impact	4,18	neutral	0,71	damaging	0,09	deleterious	3,23	22,8	0,47	0,55	disease	0,64	disease	0,71	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	0,22	high_impact	2,37	0,58	0,8	NA	NA	N	0,33	N	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5385	5385	C	T	MI.14687	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	916	306	P	S	Ccc/Tcc	-7,74	0	0	probably_damaging	1	neutral	0,43	neutral	1,14	deleterious	-3,37	deleterious	-7,65	high_impact	3,63	neutral	0,66	damaging	0,06	deleterious	4,03	23,6	0,38	0,5	neutral	0,35	disease	0,85	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	0,14	medium_impact	1,91	0,15	0,8	NA	NA	N	0,31	N	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5386	5386	C	T	MI.14688	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	917	306	P	L	cCc/cTc	4,29	0,99	0	probably_damaging	1	neutral	0,66	neutral	1,06	deleterious	-4,7	deleterious	-9,56	medium_impact	3,5	neutral	0,7	damaging	0,05	deleterious	4,56	24,4	0,24	0,45	neutral	0,48	disease	0,88	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	0,37	medium_impact	1,8	0,75	0,85	NA	NA	N	0,47	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5386	5386	C	A	MI.14689	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	917	306	P	H	cCc/cAc	4,29	0,99	0	probably_damaging	1	neutral	0,53	neutral	1,03	deleterious	-5,82	deleterious	-8,61	high_impact	4,18	neutral	0,72	damaging	0,04	deleterious	4,18	23,8	0,25	0,45	disease	0,81	disease	0,87	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	0,24	high_impact	2,37	0,18	0,8	NA	NA	P	0,59	P	0,71	polymorphism	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8378	8378	A	T	MI.1469	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	13	5	N	Y	Aat/Tat	-0,33	0,25	0	probably_damaging	1	neutral	0,22	neutral	1,69	deleterious	-3,86	deleterious	-5,27	medium_impact	3,04	neutral	1	neutral	0,69	deleterious	3,62	23,2	0,5726291	0,85	disease	0,72	neutral	0,21	disease	0,61	neutral	0,18	6	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	-0,02	medium_impact	1,51	0,34	0,85	5,88	7,06	N	0,53	P	0,66	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5386	5386	C	G	MI.14690	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	917	306	P	R	cCc/cGc	4,29	0,99	0	probably_damaging	1	neutral	0,34	neutral	1,03	deleterious	-5,55	deleterious	-8,61	high_impact	4,18	neutral	0,68	damaging	0,05	deleterious	3,73	23,3	0,16	0,45	disease	0,72	disease	0,9	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,05	high_impact	2,37	0,29	0,8	NA	NA	P	0,6	P	0,56	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5388	5388	A	G	MI.14691	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	919	307	M	V	Ata/Gta	-2,88	0	0	benign	0,02	neutral	0,51	neutral	2,03	neutral	1,76	neutral	-0,23	low_impact	0,8	neutral	0,95	neutral	0,87	neutral	1,05	10,96	0,36	0,5	neutral	0,38	neutral	0,42	neutral	0,48	neutral	0,47	1	neutral	0,46	deleterious	0,75	neutral	-6	neutral	0,17	medium_impact	0,75	medium_impact	0,22	medium_impact	-0,47	0,28	0,8	NA	NA	N	0,36	N	0,45	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5388	5388	A	T	MI.14692	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	919	307	M	L	Ata/Tta	-2,88	0	0	benign	0,02	neutral	0,67	neutral	2,02	neutral	1,53	neutral	-0,6	neutral_impact	-0,09	neutral	0,91	neutral	0,58	neutral	1,75	14,68	0,27	0,45	neutral	0,38	neutral	0,41	neutral	0,45	neutral	0,46	1	neutral	0,29	deleterious	0,83	neutral	-6	neutral	0,17	medium_impact	0,75	medium_impact	0,38	low_impact	-1,22	0,24	0,8	NA	NA	N	0,32	N	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5388	5388	A	C	MI.14693	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	919	307	M	L	Ata/Cta	-2,88	0	0	benign	0,02	neutral	0,67	neutral	2,02	neutral	1,53	neutral	-0,6	neutral_impact	-0,09	neutral	0,91	neutral	0,58	neutral	1,61	13,91	0,27	0,45	neutral	0,38	neutral	0,41	neutral	0,45	neutral	0,46	1	neutral	0,29	deleterious	0,83	neutral	-6	neutral	0,17	medium_impact	0,75	medium_impact	0,38	low_impact	-1,22	0,24	0,8	NA	NA	N	0,32	N	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5389	5389	T	A	MI.14694	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	920	307	M	K	aTa/aAa	-1,96	0	0	benign	0,05	neutral	0,31	neutral	2,09	neutral	3,3	neutral	0,28	neutral_impact	0,46	neutral	0,85	neutral	0,5	deleterious	2,23	17,72	0,19	0,45	disease	0,84	disease	0,63	disease	0,53	disease	0,59	2	neutral	0,66	deleterious	0,63	neutral	-6	neutral	0,32	medium_impact	0,37	medium_impact	0,02	medium_impact	-0,76	0,18	0,8	NA	NA	N	0,31	N	0,57	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5389	5389	T	C	MI.14695	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	920	307	M	T	aTa/aCa	-1,96	0	0	benign	0	neutral	0,42	neutral	2,11	neutral	3,6	neutral	3,13	neutral_impact	-1,79	neutral	0,97	neutral	0,93	neutral	-1,41	0	0,26	0,45	neutral	0,47	neutral	0,29	neutral	0,2	neutral	0,45	1	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	0,13	low_impact	-2,65	0,06	0,8	NA	NA	N	0,33	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5390	5390	A	T	MI.14696	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	921	307	M	I	atA/atT	1,28	0	0,02	benign	0,04	neutral	0,42	neutral	2,03	neutral	1,98	neutral	-0,63	neutral_impact	0,11	neutral	0,87	neutral	0,48	neutral	1,79	14,9	0,28	0,45	neutral	0,39	neutral	0,44	neutral	0,46	neutral	0,49	0	neutral	0,55	deleterious	0,69	neutral	-6	neutral	0,22	medium_impact	0,47	medium_impact	0,13	low_impact	-1,05	0,32	0,8	NA	NA	N	0,36	N	0,43	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5390	5390	A	C	MI.14697	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	921	307	M	I	atA/atC	1,28	0	0,02	benign	0,04	neutral	0,42	neutral	2,03	neutral	1,98	neutral	-0,63	neutral_impact	0,11	neutral	0,87	neutral	0,48	neutral	1,69	14,33	0,28	0,45	neutral	0,39	neutral	0,44	neutral	0,46	neutral	0,49	0	neutral	0,55	deleterious	0,69	neutral	-6	neutral	0,22	medium_impact	0,47	medium_impact	0,13	low_impact	-1,05	0,32	0,8	NA	NA	N	0,35	N	0,43	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5391	5391	T	C	MI.14698	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	922	308	S	P	Tct/Cct	-7,28	0	0	benign	0,02	neutral	0,22	neutral	1,91	neutral	-1,18	deleterious	-2,52	neutral_impact	0,36	neutral	0,94	neutral	0,95	deleterious	2,95	22,1	0,2	0,45	disease	0,81	disease	0,7	neutral	0,34	disease	0,53	1	neutral	0,77	deleterious	0,6	neutral	-6	neutral	0,3	medium_impact	0,75	medium_impact	-0,1	medium_impact	-0,84	0,23	0,8	NA	NA	N	0,35	N	0,69	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5391	5391	T	A	MI.14699	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	922	308	S	T	Tct/Act	-7,28	0	0	benign	0,06	neutral	0,48	neutral	2,13	neutral	0,89	neutral	0,98	neutral_impact	-1,5	neutral	0,93	neutral	0,99	neutral	1,21	11,79	0,56	0,6	neutral	0,42	neutral	0,08	neutral	0,23	neutral	0,27	5	neutral	0,46	deleterious	0,71	neutral	-6	neutral	0,16	medium_impact	0,3	medium_impact	0,19	low_impact	-2,41	0,46	0,8	NA	NA	N	0,4	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8595	8595	C	G	MI.147	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	69	23	I	M	atC/atG	4,52	0,99	0,01	possibly_damaging	0,82	neutral	0,17	neutral	4,32	neutral	-1,04	neutral	-1,56	low_impact	0,82	neutral	0,88	neutral	0,37	deleterious	2,95	22,1	0,43	0,65	disease	0,74	neutral	0,41	disease	0,53	disease	0,67	3	neutral	0,91	neutral	0,18	neutral	-3	deleterious	0,65	low_impact	-1,38	medium_impact	-0,1	medium_impact	-0,4	0,7	0,9	19,03	10,37	N	0,5	N	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8378	8378	A	C	MI.1470	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	13	5	N	H	Aat/Cat	-0,33	0,25	0	probably_damaging	1	neutral	0,08	neutral	1,71	neutral	-2,73	deleterious	-2,96	medium_impact	3,04	neutral	0,99	neutral	0,55	deleterious	2,97	22,1	0,6294906	0,85	disease	0,57	neutral	0,19	disease	0,59	neutral	0,19	6	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	-0,31	medium_impact	1,51	0,29	0,85	5,88	7,06	N	0,52	P	0,33	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5391	5391	T	G	MI.14700	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	922	308	S	A	Tct/Gct	-7,28	0	0	benign	0,34	neutral	0,5	neutral	1,89	neutral	-1,6	neutral	-1,3	neutral_impact	0,74	neutral	0,89	neutral	0,85	deleterious	2,68	20,7	0,49	0,55	neutral	0,35	neutral	0,31	neutral	0,47	neutral	0,47	1	neutral	0,42	deleterious	0,58	neutral	-6	deleterious	0,44	medium_impact	-0,53	medium_impact	0,21	medium_impact	-0,52	0,2	0,8	NA	NA	N	0,36	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5392	5392	C	A	MI.14701	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	923	308	S	Y	tCt/tAt	-1,03	0	0	probably_damaging	0,93	neutral	1	neutral	1,87	neutral	-2,23	deleterious	-2,89	low_impact	1,43	neutral	0,9	neutral	0,55	deleterious	4,25	23,9	0,23	0,45	neutral	0,41	disease	0,67	disease	0,63	disease	0,7	4	neutral	0,93	deleterious	0,54	neutral	-2	deleterious	0,71	low_impact	-1,83	high_impact	1,87	medium_impact	0,06	0,23	0,8	NA	NA	N	0,2	N	0,77	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5392	5392	C	G	MI.14702	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	923	308	S	C	tCt/tGt	-1,03	0	0	probably_damaging	0,95	neutral	0,17	neutral	1,83	deleterious	-4,89	neutral	-2,42	medium_impact	1,98	neutral	0,79	neutral	0,42	deleterious	3,66	23,2	0,2	0,45	disease	0,82	disease	0,67	disease	0,59	disease	0,69	4	neutral	0,97	neutral	0,11	deleterious	1	deleterious	0,75	low_impact	-1,97	medium_impact	-0,17	medium_impact	0,52	0,26	0,8	NA	NA	N	0,29	N	0,52	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5392	5392	C	T	MI.14703	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	923	308	S	F	tCt/tTt	-1,03	0	0	possibly_damaging	0,82	neutral	0,71	neutral	1,85	neutral	-2,91	deleterious	-2,71	low_impact	0,94	neutral	0,92	neutral	0,76	deleterious	4,23	23,9	0,23	0,45	disease	0,53	disease	0,69	disease	0,62	disease	0,7	4	neutral	0,78	neutral	0,45	neutral	-3	deleterious	0,69	low_impact	-1,4	medium_impact	0,42	medium_impact	-0,35	0,1	0,8	NA	NA	N	0,21	N	0,79	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5394	5394	A	C	MI.14704	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	925	309	N	H	Aac/Cac	-13,06	0	0	probably_damaging	1	neutral	0,54	neutral	1,92	neutral	-2,24	deleterious	-4,68	medium_impact	3,21	neutral	0,86	damaging	0,1	deleterious	3,23	22,8	0,71	0,75	disease	0,65	disease	0,57	disease	0,58	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	0,25	medium_impact	1,56	0,09	0,8	0,58	8,67	N	0,2	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5394	5394	A	G	MI.14705	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	925	309	N	D	Aac/Gac	-13,06	0	0	probably_damaging	1	neutral	0,2	neutral	1,91	deleterious	-3,25	deleterious	-4,64	medium_impact	3,21	neutral	0,89	damaging	0,14	deleterious	3,97	23,6	0,74	0,75	disease	0,75	disease	0,57	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,13	medium_impact	1,56	0,31	0,8	0,58	8,67	N	0,41	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5394	5394	A	T	MI.14706	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	925	309	N	Y	Aac/Tac	-13,06	0	0	probably_damaging	1	neutral	1	neutral	1,93	neutral	-1,84	deleterious	-7,48	medium_impact	3,21	neutral	0,9	damaging	0,22	deleterious	3,89	23,5	0,25	0,45	neutral	0,38	disease	0,7	disease	0,58	disease	0,67	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,73	low_impact	-3,54	high_impact	1,87	medium_impact	1,56	0,19	0,8	0,58	8,67	N	0,23	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5395	5395	A	T	MI.14707	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	926	309	N	I	aAc/aTc	8,45	1	0	probably_damaging	1	neutral	0,41	neutral	2,04	neutral	0,49	deleterious	-8,4	low_impact	1,83	neutral	0,87	damaging	0,23	deleterious	3,99	23,6	0,29	0,45	disease	0,61	disease	0,7	neutral	0,43	neutral	0,26	5	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	0,12	medium_impact	0,4	0,26	0,8	0,58	8,67	P	0,56	P	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5395	5395	A	C	MI.14708	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	926	309	N	T	aAc/aCc	8,45	1	0	probably_damaging	1	neutral	0,4	neutral	2,1	neutral	1,08	deleterious	-5,53	low_impact	0,84	neutral	0,88	neutral	0,33	deleterious	2,42	18,93	0,61	0,65	disease	0,62	neutral	0,18	neutral	0,36	neutral	0,39	2	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,11	medium_impact	-0,44	0,19	0,8	0,58	8,67	P	0,59	P	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5395	5395	A	G	MI.14709	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	926	309	N	S	aAc/aGc	8,45	1	0	probably_damaging	1	neutral	0,41	neutral	2,2	neutral	1,7	deleterious	-4,5	low_impact	1,57	neutral	0,82	neutral	0,77	deleterious	2,15	17,17	0,7	0,75	neutral	0,35	neutral	0,37	neutral	0,4	neutral	0,45	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,68	low_impact	-3,54	medium_impact	0,12	medium_impact	0,18	0,25	0,8	0,58	8,67	P	0,57	P	0,8	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8378	8378	A	G	MI.1471	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	13	5	N	D	Aat/Gat	-0,33	0,25	0	probably_damaging	0,97	neutral	0,86	neutral	1,95	neutral	1,96	neutral	1,74	neutral_impact	-0,36	neutral	0,96	neutral	0,9	neutral	1	10,65	0,80179446	0,9	neutral	0,11	neutral	0,03	neutral	0,37	neutral	0,06	9	neutral	0,97	neutral	0,45	neutral	-2	deleterious	0,64	low_impact	-2,19	medium_impact	0,74	low_impact	-1,41	0,55	0,85	5,88	7,06	N	0,31	N	0,13	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5396	5396	C	A	MI.14710	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	927	309	N	K	aaC/aaA	4,52	1	0	probably_damaging	1	neutral	0,3	neutral	1,92	neutral	-2,2	deleterious	-5,56	medium_impact	2,87	neutral	0,86	damaging	0,1	deleterious	4,56	24,4	0,67	0,7	disease	0,63	disease	0,67	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0	medium_impact	1,27	0,42	0,8	0,58	8,67	N	0,48	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5396	5396	C	G	MI.14711	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	927	309	N	K	aaC/aaG	4,52	1	0	probably_damaging	1	neutral	0,3	neutral	1,92	neutral	-2,2	deleterious	-5,56	medium_impact	2,87	neutral	0,86	damaging	0,1	deleterious	4,08	23,7	0,67	0,7	disease	0,63	disease	0,67	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0	medium_impact	1,27	0,42	0,8	0,58	8,67	N	0,49	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5397	5397	A	G	MI.14712	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	928	310	N	D	Aac/Gac	-4,96	0	0	possibly_damaging	0,87	neutral	0,23	neutral	1,82	neutral	-2,75	deleterious	-4,37	medium_impact	3,44	neutral	0,88	damaging	0,18	deleterious	3,83	23,4	0,78	0,8	disease	0,89	disease	0,77	disease	0,68	disease	0,69	4	neutral	0,91	neutral	0,18	NA	0	deleterious	0,78	low_impact	-1,55	medium_impact	-0,08	medium_impact	1,75	0,27	0,8	NA	NA	N	0,42	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5397	5397	A	T	MI.14713	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	928	310	N	Y	Aac/Tac	-4,96	0	0	probably_damaging	0,99	neutral	1	neutral	1,83	neutral	-2,28	deleterious	-7,07	medium_impact	2,98	neutral	0,85	damaging	0,19	deleterious	3,62	23,2	0,2	0,45	disease	0,75	disease	0,88	disease	0,68	disease	0,71	4	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,83	low_impact	-2,62	high_impact	1,87	medium_impact	1,36	0,28	0,8	NA	NA	N	0,19	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5397	5397	A	C	MI.14714	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	928	310	N	H	Aac/Cac	-4,96	0	0	probably_damaging	0,99	neutral	0,54	neutral	1,84	neutral	-2,22	deleterious	-4,46	high_impact	3,79	neutral	0,89	damaging	0,16	deleterious	3,08	22,5	0,6	0,65	disease	0,84	disease	0,8	disease	0,61	disease	0,63	3	deleterious	0,99	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-2,62	medium_impact	0,25	high_impact	2,05	0,17	0,8	NA	NA	N	0,31	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5398	5398	A	T	MI.14715	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	929	310	N	I	aAc/aTc	1,51	0	0	probably_damaging	0,97	neutral	0,42	neutral	1,85	neutral	-1,93	deleterious	-7,85	medium_impact	3,1	neutral	0,9	neutral	0,54	deleterious	4,04	23,7	0,26	0,45	disease	0,53	disease	0,9	disease	0,63	disease	0,58	2	neutral	0,97	neutral	0,23	deleterious	1	deleterious	0,78	low_impact	-2,18	medium_impact	0,13	medium_impact	1,47	0,29	0,8	NA	NA	N	0,42	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5398	5398	A	C	MI.14716	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	929	310	N	T	aAc/aCc	1,51	0	0	possibly_damaging	0,77	neutral	0,43	neutral	1,99	neutral	-0,05	deleterious	-4,94	low_impact	1,62	neutral	0,91	neutral	0,73	deleterious	3,45	23	0,52	0,6	disease	0,6	disease	0,75	neutral	0,41	neutral	0,23	5	neutral	0,77	neutral	0,33	neutral	-3	deleterious	0,76	low_impact	-1,28	medium_impact	0,14	medium_impact	0,22	0,3	0,8	NA	NA	N	0,35	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5398	5398	A	G	MI.14717	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	929	310	N	S	aAc/aGc	1,51	0	0	benign	0,34	neutral	0,44	neutral	1,93	neutral	-0,58	deleterious	-4,08	medium_impact	2,16	neutral	0,92	neutral	0,74	deleterious	2,14	17,13	0,73	0,75	disease	0,53	disease	0,7	neutral	0,44	neutral	0,21	6	neutral	0,48	deleterious	0,55	neutral	-3	deleterious	0,58	medium_impact	-0,53	medium_impact	0,15	medium_impact	0,67	0,23	0,8	NA	NA	N	0,37	N	0,8	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5399	5399	C	A	MI.14718	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	930	310	N	K	aaC/aaA	0,59	0	0	possibly_damaging	0,89	neutral	0,33	neutral	1,87	neutral	-1,52	deleterious	-5,23	medium_impact	3,24	neutral	0,86	damaging	0,18	deleterious	4,6	24,4	0,62	0,65	disease	0,8	disease	0,85	disease	0,67	disease	0,69	4	neutral	0,9	neutral	0,22	NA	0	deleterious	0,82	low_impact	-1,63	medium_impact	0,04	medium_impact	1,58	0,45	0,8	NA	NA	N	0,34	N	0,99	polymorphism	1	0,07	rs28631235	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5399	5399	C	G	MI.14719	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	930	310	N	K	aaC/aaG	0,59	0	0	possibly_damaging	0,89	neutral	0,33	neutral	1,87	neutral	-1,52	deleterious	-5,23	medium_impact	3,24	neutral	0,86	damaging	0,18	deleterious	4,09	23,7	0,62	0,65	disease	0,8	disease	0,85	disease	0,67	disease	0,69	4	neutral	0,9	neutral	0,22	NA	0	deleterious	0,82	low_impact	-1,63	medium_impact	0,04	medium_impact	1,58	0,45	0,8	NA	NA	N	0,3	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8379	8379	A	C	MI.1472	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	14	5	N	T	aAt/aCt	3,37	0,99	0	probably_damaging	0,98	neutral	0,07	neutral	1,72	neutral	-2	deleterious	-3,29	medium_impact	3,04	neutral	0,99	neutral	0,66	deleterious	3,17	22,7	0,6294906	0,85	neutral	0,46	neutral	0,19	disease	0,55	neutral	0,21	6	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,72	low_impact	-2,36	medium_impact	-0,34	medium_impact	1,51	0,41	0,85	5,88	7,06	P	0,67	P	0,32	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5400	5400	G	A	MI.14720	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	931	311	V	M	Gta/Ata	-1,26	0	0	benign	0,04	neutral	0,24	neutral	1,98	neutral	-0,31	neutral	1,56	neutral_impact	-2,02	neutral	0,9	neutral	0,89	neutral	1,63	13,99	0,32	0,5	neutral	0,46	neutral	0,13	neutral	0,19	neutral	0,28	5	neutral	0,74	deleterious	0,6	neutral	-6	neutral	0,19	medium_impact	0,47	medium_impact	-0,07	low_impact	-2,85	0,7	0,85	6,92	8,85	N	0,52	P	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5400	5400	G	C	MI.14721	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	931	311	V	L	Gta/Cta	-1,26	0	0	benign	0,06	neutral	0,67	neutral	2,02	neutral	0,32	neutral	0,13	neutral_impact	-0,35	neutral	0,85	neutral	0,89	deleterious	0,45	7,02	0,37	0,5	neutral	0,37	neutral	0,29	neutral	0,34	neutral	0,43	1	neutral	0,25	deleterious	0,81	neutral	-6	neutral	0,17	medium_impact	0,3	medium_impact	0,38	low_impact	-1,44	0,56	0,8	6,92	8,85	N	0,26	N	0,34	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5400	5400	G	T	MI.14722	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	931	311	V	L	Gta/Tta	-1,26	0	0	benign	0,06	neutral	0,67	neutral	2,02	neutral	0,32	neutral	0,13	neutral_impact	-0,35	neutral	0,85	neutral	0,89	deleterious	0,57	7,94	0,37	0,5	neutral	0,37	neutral	0,29	neutral	0,34	neutral	0,43	1	neutral	0,25	deleterious	0,81	neutral	-6	neutral	0,17	medium_impact	0,3	medium_impact	0,38	low_impact	-1,44	0,56	0,8	6,92	8,85	N	0,26	N	0,34	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5401	5401	T	G	MI.14723	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	932	311	V	G	gTa/gGa	-0,34	0	0	benign	0,14	neutral	0,33	neutral	1,97	neutral	-0,61	deleterious	-3,37	neutral_impact	-0,82	neutral	0,88	neutral	0,57	deleterious	2,16	17,28	0,09	0,4	disease	0,77	neutral	0,39	neutral	0,44	disease	0,65	3	neutral	0,61	deleterious	0,6	neutral	-6	neutral	0,36	medium_impact	-0,08	medium_impact	0,04	low_impact	-1,84	0,13	0,8	6,92	8,85	N	0,35	N	0,51	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5401	5401	T	A	MI.14724	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	932	311	V	E	gTa/gAa	-0,34	0	0	benign	0,27	neutral	0,27	neutral	1,92	neutral	-1,94	neutral	-2,46	low_impact	0,9	neutral	0,9	neutral	0,53	deleterious	3,34	22,9	0,07	0,35	disease	0,88	disease	0,68	neutral	0,49	disease	0,63	3	neutral	0,67	deleterious	0,5	neutral	-6	deleterious	0,58	medium_impact	-0,4	medium_impact	-0,03	medium_impact	-0,39	0,21	0,8	6,92	8,85	N	0,37	N	0,47	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5401	5401	T	C	MI.14725	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	932	311	V	A	gTa/gCa	-0,34	0	0	benign	0	neutral	0,52	neutral	2,04	neutral	0,44	neutral	-1,32	neutral_impact	-0,77	neutral	0,93	neutral	0,84	deleterious	0,08	3,35	0,37	0,5	disease	0,59	neutral	0,21	neutral	0,4	neutral	0,46	1	neutral	0,47	deleterious	0,76	neutral	-6	neutral	0,18	medium_impact	1,95	medium_impact	0,23	low_impact	-1,79	0,25	0,8	6,92	8,85	N	0,33	N	0,03	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5403	5403	A	C	MI.14726	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	934	312	K	Q	Aaa/Caa	-3,34	0	0	probably_damaging	1	neutral	0,3	neutral	1,9	neutral	-1,38	deleterious	-3,8	medium_impact	3,02	neutral	0,87	damaging	0,15	deleterious	3,6	23,2	0,43	0,55	disease	0,66	disease	0,63	disease	0,64	disease	0,61	2	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0	medium_impact	1,4	0,21	0,8	NA	NA	N	0,33	N	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5403	5403	A	G	MI.14727	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	934	312	K	E	Aaa/Gaa	-3,34	0	0	probably_damaging	1	neutral	0,28	neutral	1,9	neutral	-1,44	deleterious	-3,81	medium_impact	2,33	neutral	0,88	damaging	0,14	deleterious	4,15	23,8	0,22	0,45	disease	0,59	disease	0,73	disease	0,61	disease	0,61	2	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	-0,02	medium_impact	0,82	0,36	0,8	NA	NA	N	0,32	N	0,91	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5404	5404	A	T	MI.14728	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	935	312	K	M	aAa/aTa	2,9	0,88	0	probably_damaging	1	neutral	0,23	neutral	1,98	neutral	-0,22	deleterious	-5,68	low_impact	0,84	neutral	0,86	neutral	0,56	deleterious	3,83	23,4	0,15	0,4	disease	0,57	neutral	0,2	neutral	0,46	neutral	0,46	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	-0,08	medium_impact	-0,44	0,13	0,8	NA	NA	N	0,41	N	0,45	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5404	5404	A	C	MI.14729	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	935	312	K	T	aAa/aCa	2,9	0,88	0	probably_damaging	1	neutral	0,41	neutral	2,1	neutral	0,73	deleterious	-5,71	low_impact	1,34	neutral	0,87	damaging	0,2	deleterious	3,54	23,1	0,2	0,45	disease	0,54	neutral	0,47	neutral	0,39	disease	0,52	0	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,75	low_impact	-3,54	medium_impact	0,12	medium_impact	-0,02	0,12	0,8	NA	NA	N	0,36	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8379	8379	A	T	MI.1473	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	14	5	N	I	aAt/aTt	3,37	0,99	0	probably_damaging	1	neutral	0,06	neutral	1,69	deleterious	-3,77	deleterious	-5,6	medium_impact	2,49	neutral	0,99	neutral	0,58	deleterious	3,65	23,2	0,49421446	0,85	disease	0,72	neutral	0,23	disease	0,56	neutral	0,18	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	-0,38	medium_impact	1,04	0,28	0,85	5,88	7,06	P	0,64	P	0,64	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5405	5405	A	C	MI.14730	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	936	312	K	N	aaA/aaC	2,44	0,88	0	probably_damaging	1	neutral	0,32	neutral	1,88	neutral	-1,81	deleterious	-4,76	medium_impact	2,4	neutral	0,87	damaging	0,18	deleterious	3,93	23,5	0,63	0,7	neutral	0,42	disease	0,59	disease	0,58	neutral	0,48	0	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,03	medium_impact	0,88	0,28	0,8	NA	NA	N	0,4	N	0,69	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5405	5405	A	T	MI.14731	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	936	312	K	N	aaA/aaT	2,44	0,88	0	probably_damaging	1	neutral	0,32	neutral	1,88	neutral	-1,81	deleterious	-4,76	medium_impact	2,4	neutral	0,87	damaging	0,18	deleterious	3,99	23,6	0,63	0,7	neutral	0,42	disease	0,59	disease	0,58	neutral	0,48	0	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,03	medium_impact	0,88	0,28	0,8	NA	NA	N	0,41	N	0,69	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5406	5406	A	C	MI.14732	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	937	313	M	L	Ata/Cta	1,51	0,79	0	benign	0,09	neutral	0,67	neutral	2,03	neutral	0,26	neutral	-1,72	neutral_impact	0,35	neutral	0,87	neutral	0,95	neutral	1,74	14,63	0,36	0,5	disease	0,66	neutral	0,31	neutral	0,35	disease	0,61	2	neutral	0,23	deleterious	0,79	neutral	-6	neutral	0,37	medium_impact	0,12	medium_impact	0,38	medium_impact	-0,85	0,3	0,8	1,73	8,19	N	0,28	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5406	5406	A	T	MI.14733	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	937	313	M	L	Ata/Tta	1,51	0,79	0	benign	0,09	neutral	0,67	neutral	2,03	neutral	0,26	neutral	-1,72	neutral_impact	0,35	neutral	0,87	neutral	0,95	deleterious	1,82	15,08	0,36	0,5	disease	0,66	neutral	0,31	neutral	0,35	disease	0,61	2	neutral	0,23	deleterious	0,79	neutral	-6	neutral	0,37	medium_impact	0,12	medium_impact	0,38	medium_impact	-0,85	0,3	0,8	1,73	8,19	N	0,29	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5406	5406	A	G	MI.14734	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	937	313	M	V	Ata/Gta	1,51	0,79	0	benign	0,14	neutral	0,52	neutral	1,93	neutral	-0,98	neutral	-2,23	medium_impact	2,17	neutral	0,92	neutral	0,59	deleterious	2,64	20,4	0,36	0,5	disease	0,67	neutral	0,43	disease	0,53	disease	0,63	3	neutral	0,39	deleterious	0,69	neutral	-3	neutral	0,39	medium_impact	-0,08	medium_impact	0,23	medium_impact	0,68	0,25	0,8	1,73	8,19	N	0,3	N	0,78	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5407	5407	T	A	MI.14735	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	938	313	M	K	aTa/aAa	-0,57	0,01	0	possibly_damaging	0,8	neutral	0,32	neutral	1,93	neutral	-0,93	deleterious	-4,92	neutral_impact	0,67	neutral	0,81	neutral	0,34	deleterious	4,19	23,8	0,13	0,4	disease	0,58	neutral	0,32	disease	0,56	disease	0,62	2	neutral	0,83	neutral	0,26	neutral	-3	deleterious	0,69	low_impact	-1,35	medium_impact	0,03	medium_impact	-0,58	0,23	0,8	1,73	8,19	N	0,31	N	0,97	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5407	5407	T	C	MI.14736	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	938	313	M	T	aTa/aCa	-0,57	0,01	0	possibly_damaging	0,67	neutral	0,43	neutral	2,05	neutral	0,43	deleterious	-4,33	low_impact	0,98	neutral	0,84	neutral	0,82	deleterious	1,85	15,27	0,19	0,45	disease	0,64	neutral	0,43	neutral	0,39	disease	0,59	2	neutral	0,67	neutral	0,38	neutral	-3	deleterious	0,67	low_impact	-1,08	medium_impact	0,14	medium_impact	-0,32	0,06	0,8	1,73	8,19	N	0,3	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5408	5408	A	T	MI.14737	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	939	313	M	I	atA/atT	1,98	0,06	0	benign	0,03	neutral	0,43	neutral	1,98	neutral	-0,25	neutral	-2,03	low_impact	1,62	neutral	0,9	neutral	0,96	deleterious	1,94	15,85	0,31	0,45	disease	0,73	neutral	0,38	neutral	0,36	disease	0,64	3	neutral	0,55	deleterious	0,7	neutral	-6	neutral	0,24	medium_impact	0,59	medium_impact	0,14	medium_impact	0,22	0,33	0,8	1,73	8,19	N	0,43	N	0,57	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5408	5408	A	C	MI.14738	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	939	313	M	I	atA/atC	1,98	0,06	0	benign	0,03	neutral	0,43	neutral	1,98	neutral	-0,25	neutral	-2,03	low_impact	1,62	neutral	0,9	neutral	0,96	deleterious	1,86	15,37	0,31	0,45	disease	0,73	neutral	0,38	neutral	0,36	disease	0,64	3	neutral	0,55	deleterious	0,7	neutral	-6	neutral	0,24	medium_impact	0,59	medium_impact	0,14	medium_impact	0,22	0,33	0,8	1,73	8,19	N	0,42	N	0,57	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5409	5409	A	G	MI.14739	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	940	314	K	E	Aaa/Gaa	-1,03	0	0	benign	0,34	neutral	0,28	neutral	1,72	neutral	-2,6	deleterious	-3,31	high_impact	3,55	neutral	0,91	neutral	0,43	deleterious	4,16	23,8	0,23	0,45	disease	0,68	disease	0,66	disease	0,51	disease	0,51	0	neutral	0,66	deleterious	0,47	neutral	-2	deleterious	0,61	medium_impact	-0,53	medium_impact	-0,02	medium_impact	1,84	0,52	0,8	7,2	8,29	N	0,43	N	0,62	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8379	8379	A	G	MI.1474	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	14	5	N	S	aAt/aGt	3,37	0,99	0	probably_damaging	0,97	neutral	0,34	neutral	1,8	neutral	-1,35	neutral	-2,29	medium_impact	2,35	neutral	1	neutral	0,64	deleterious	2,83	21,5	0,74880421	0,85	neutral	0,31	neutral	0,13	disease	0,52	neutral	0,18	6	neutral	0,98	neutral	0,19	deleterious	1	deleterious	0,68	low_impact	-2,19	medium_impact	0,13	medium_impact	0,92	0,29	0,85	5,88	7,06	P	0,64	P	0,35	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5409	5409	A	C	MI.14740	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	940	314	K	Q	Aaa/Caa	-1,03	0	0	possibly_damaging	0,73	neutral	0,3	neutral	1,72	neutral	-2,49	deleterious	-3,16	low_impact	1,42	neutral	0,85	neutral	0,86	deleterious	2,27	17,95	0,4	0,5	disease	0,72	neutral	0,21	neutral	0,3	disease	0,52	0	neutral	0,79	neutral	0,29	neutral	-3	deleterious	0,67	low_impact	-1,19	medium_impact	0	medium_impact	0,05	0,33	0,8	7,2	8,29	N	0,42	N	0,26	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5410	5410	A	T	MI.14741	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	941	314	K	M	aAa/aTa	1,28	0	0	probably_damaging	0,93	neutral	0,23	neutral	1,68	deleterious	-4,18	deleterious	-4,48	medium_impact	2,4	neutral	0,87	neutral	0,88	deleterious	2,91	21,9	0,12	0,4	neutral	0,48	neutral	0,39	neutral	0,34	neutral	0,42	2	neutral	0,95	neutral	0,15	deleterious	1	deleterious	0,71	low_impact	-1,83	medium_impact	-0,08	medium_impact	0,88	0,23	0,8	7,2	8,29	N	0,49	N	0,33	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5410	5410	A	C	MI.14742	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	941	314	K	T	aAa/aCa	1,28	0	0	benign	0,03	neutral	0,4	neutral	1,76	neutral	-1,89	deleterious	-4,69	medium_impact	2,2	neutral	0,96	neutral	0,95	deleterious	2,58	19,99	0,17	0,45	disease	0,63	neutral	0,49	neutral	0,33	neutral	0,48	0	neutral	0,58	deleterious	0,69	neutral	-3	neutral	0,27	medium_impact	0,59	medium_impact	0,11	medium_impact	0,71	0,17	0,8	7,2	8,29	N	0,4	N	0,17	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5411	5411	A	C	MI.14743	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	942	314	K	N	aaA/aaC	0,13	0	0	benign	0,02	neutral	0,33	neutral	1,8	neutral	-1,35	deleterious	-3,91	medium_impact	2,86	neutral	0,88	neutral	0,81	deleterious	2,86	21,7	0,52	0,6	disease	0,74	disease	0,52	neutral	0,35	disease	0,51	0	neutral	0,66	deleterious	0,66	neutral	-3	neutral	0,27	medium_impact	0,75	medium_impact	0,04	medium_impact	1,26	0,32	0,8	7,2	8,29	N	0,42	N	0,59	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5411	5411	A	T	MI.14744	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	942	314	K	N	aaA/aaT	0,13	0	0	benign	0,02	neutral	0,33	neutral	1,8	neutral	-1,35	deleterious	-3,91	medium_impact	2,86	neutral	0,88	neutral	0,81	deleterious	2,87	21,7	0,52	0,6	disease	0,74	disease	0,52	neutral	0,35	disease	0,51	0	neutral	0,66	deleterious	0,66	neutral	-3	neutral	0,27	medium_impact	0,75	medium_impact	0,04	medium_impact	1,26	0,32	0,8	7,2	8,29	N	0,43	N	0,59	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5412	5412	T	C	MI.14745	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	943	315	W	R	Tga/Cga	-1,72	0	0	probably_damaging	1	neutral	0,4	neutral	0,79	deleterious	-6,97	deleterious	-13,39	high_impact	3,83	neutral	0,8	damaging	0,13	deleterious	3,75	23,3	0,06	0,35	disease	0,73	disease	0,87	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	0,11	high_impact	2,08	0,03	0,8	NA	NA	N	0,44	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5412	5412	T	G	MI.14746	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	943	315	W	G	Tga/Gga	-1,72	0	0	probably_damaging	1	neutral	0,33	neutral	0,8	deleterious	-6,33	deleterious	-12,43	high_impact	3,63	neutral	0,82	damaging	0,13	deleterious	4,06	23,7	0,05	0,35	disease	0,73	disease	0,79	disease	0,8	disease	0,77	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,04	medium_impact	1,91	0,06	0,8	NA	NA	N	0,43	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5413	5413	G	T	MI.14747	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	944	315	W	L	tGa/tTa	3,6	0,95	0	probably_damaging	1	neutral	0,72	neutral	0,85	deleterious	-4,69	deleterious	-12,43	high_impact	3,83	neutral	0,91	damaging	0,12	deleterious	4,39	24,1	0,09	0,35	disease	0,62	disease	0,74	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	0,44	high_impact	2,08	0,06	0,8	NA	NA	N	0,53	P	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5413	5413	G	C	MI.14748	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	944	315	W	S	tGa/tCa	3,6	0,95	0	probably_damaging	1	neutral	0,44	neutral	0,82	deleterious	-5,56	deleterious	-13,39	high_impact	3,83	neutral	0,92	neutral	0,28	deleterious	4,09	23,7	0,07	0,35	disease	0,54	disease	0,89	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	0,15	high_impact	2,08	0,05	0,8	NA	NA	P	0,61	P	0,95	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5414	5414	A	C	MI.14749	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	945	315	W	C	tgA/tgC	1,51	0,93	0	probably_damaging	1	neutral	0,18	neutral	0,79	deleterious	-7,54	deleterious	-12,43	high_impact	4,18	neutral	0,77	damaging	0,11	deleterious	4,15	23,8	0,06	0,35	disease	0,67	disease	0,86	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,16	high_impact	2,37	0,05	0,8	NA	NA	P	0,53	P	0,96	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8380	8380	T	A	MI.1475	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	15	5	N	K	aaT/aaA	5,45	0,99	0	probably_damaging	0,98	neutral	0,11	neutral	1,76	neutral	-1,33	deleterious	-3,29	medium_impact	3,04	neutral	0,99	neutral	0,52	deleterious	4,23	23,9	0,70300388	0,85	neutral	0,37	neutral	0,21	disease	0,55	neutral	0,21	6	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,74	low_impact	-2,36	medium_impact	-0,22	medium_impact	1,51	0,46	0,85	5,88	7,06	P	0,69	P	0,43	polymorphism	0,98	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5414	5414	A	T	MI.14750	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	945	315	W	C	tgA/tgT	1,51	0,93	0	probably_damaging	1	neutral	0,18	neutral	0,79	deleterious	-7,54	deleterious	-12,43	high_impact	4,18	neutral	0,77	damaging	0,11	deleterious	4,24	23,9	0,06	0,35	disease	0,67	disease	0,86	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,16	high_impact	2,37	0,05	0,8	NA	NA	P	0,53	P	0,96	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5415	5415	C	A	MI.14751	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	946	316	Q	K	Cag/Aag	-0,11	0	0	probably_damaging	0,99	neutral	0,3	neutral	2,08	neutral	1,29	neutral	-2,46	low_impact	1,84	neutral	0,85	neutral	0,66	deleterious	2,85	21,6	0,33	0,5	disease	0,58	disease	0,59	neutral	0,39	disease	0,52	0	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,76	low_impact	-2,62	medium_impact	0	medium_impact	0,4	0,2	0,8	9,51	8,59	N	0,32	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5415	5415	C	G	MI.14752	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	946	316	Q	E	Cag/Gag	-0,11	0	0	probably_damaging	0,99	neutral	0,27	neutral	2,02	neutral	0,41	neutral	-2,31	medium_impact	2,82	neutral	0,89	neutral	0,41	deleterious	3,17	22,7	0,37	0,5	disease	0,76	disease	0,51	disease	0,62	disease	0,69	4	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-2,62	medium_impact	-0,03	medium_impact	1,23	0,44	0,8	9,51	8,59	N	0,43	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5416	5416	A	T	MI.14753	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	947	316	Q	L	cAg/cTg	-0,11	0	0	probably_damaging	1	neutral	0,75	neutral	1,97	neutral	-0,82	deleterious	-5,5	medium_impact	2,19	neutral	0,91	neutral	0,85	deleterious	2,56	19,88	0,13	0,4	neutral	0,37	disease	0,53	neutral	0,5	neutral	0,48	0	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,47	medium_impact	0,7	0,05	0,8	9,51	8,59	N	0,29	N	0,44	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5416	5416	A	C	MI.14754	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	947	316	Q	P	cAg/cCg	-0,11	0	0	probably_damaging	1	neutral	0,22	neutral	1,98	neutral	-0,73	deleterious	-4,89	medium_impact	2,62	neutral	0,93	neutral	0,7	deleterious	3,25	22,8	0,08	0,35	disease	0,79	disease	0,78	disease	0,63	disease	0,75	5	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,88	low_impact	-3,54	medium_impact	-0,1	medium_impact	1,06	0,2	0,8	9,51	8,59	N	0,44	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5416	5416	A	G	MI.14755	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	947	316	Q	R	cAg/cGg	-0,11	0	0	probably_damaging	0,99	neutral	0,45	neutral	2,62	neutral	3,83	deleterious	-2,54	neutral_impact	0,28	neutral	0,91	neutral	0,88	neutral	1,79	14,93	0,46	0,55	disease	0,68	neutral	0,15	neutral	0,32	neutral	0,34	3	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,73	low_impact	-2,62	medium_impact	0,16	medium_impact	-0,91	0,13	0,8	9,51	8,59	N	0,44	N	0,45	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5417	5417	G	C	MI.14756	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	948	316	Q	H	caG/caC	0,36	0	0,19	probably_damaging	1	neutral	0,55	neutral	1,99	neutral	-0,24	deleterious	-3,91	low_impact	1,34	neutral	0,86	neutral	0,96	deleterious	2,2	17,49	0,33	0,5	disease	0,68	neutral	0,19	neutral	0,34	neutral	0,48	0	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,75	low_impact	-3,54	medium_impact	0,26	medium_impact	-0,02	0,32	0,8	9,51	8,59	N	0,33	N	0,32	polymorphism	1	0,06	rs386828968	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5417	5417	G	T	MI.14757	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	948	316	Q	H	caG/caT	0,36	0	0,19	probably_damaging	1	neutral	0,55	neutral	1,99	neutral	-0,24	deleterious	-3,91	low_impact	1,34	neutral	0,86	neutral	0,96	deleterious	2,26	17,88	0,33	0,5	disease	0,68	neutral	0,19	neutral	0,34	neutral	0,48	0	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,75	low_impact	-3,54	medium_impact	0,26	medium_impact	-0,02	0,32	0,8	9,51	8,59	N	0,33	N	0,32	polymorphism	1	0,06	rs386828968	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5418	5418	T	A	MI.14758	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	949	317	F	I	Ttt/Att	-6,35	0	0,01	benign	0,07	neutral	0,56	neutral	2,01	neutral	0,2	deleterious	-4,23	medium_impact	1,97	neutral	0,85	neutral	0,88	deleterious	2,82	21,5	0,31	0,45	disease	0,67	neutral	0,38	neutral	0,39	disease	0,63	3	neutral	0,37	deleterious	0,75	neutral	-3	neutral	0,22	medium_impact	0,23	medium_impact	0,27	medium_impact	0,51	0,29	0,8	8,65	9,18	N	0,28	N	0,41	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5418	5418	T	C	MI.14759	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	949	317	F	L	Ttt/Ctt	-6,35	0	0,01	benign	0	neutral	0,91	neutral	2,21	neutral	1,72	deleterious	-4,04	low_impact	0,86	neutral	0,97	neutral	0,96	neutral	0,96	10,44	0,27	0,45	neutral	0,5	neutral	0,3	neutral	0,33	neutral	0,29	4	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	0,77	medium_impact	-0,42	0,33	0,8	8,65	9,18	N	0,24	N	0,25	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8380	8380	T	G	MI.1476	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	15	5	N	K	aaT/aaG	5,45	0,99	0	probably_damaging	0,98	neutral	0,11	neutral	1,76	neutral	-1,33	deleterious	-3,29	medium_impact	3,04	neutral	0,99	neutral	0,52	deleterious	3,93	23,5	0,70300388	0,85	neutral	0,37	neutral	0,21	disease	0,55	neutral	0,21	6	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,74	low_impact	-2,36	medium_impact	-0,22	medium_impact	1,51	0,46	0,85	5,88	7,06	P	0,69	P	0,43	polymorphism	0,98	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5418	5418	T	G	MI.14760	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	949	317	F	V	Ttt/Gtt	-6,35	0	0,01	benign	0,11	neutral	0,52	neutral	1,98	neutral	-0,27	deleterious	-5,05	medium_impact	2,12	neutral	0,94	neutral	0,93	deleterious	2,35	18,49	0,26	0,45	disease	0,6	disease	0,57	disease	0,53	disease	0,5	0	neutral	0,39	deleterious	0,71	neutral	-3	neutral	0,23	medium_impact	0,03	medium_impact	0,23	medium_impact	0,64	0,28	0,8	8,65	9,18	N	0,31	N	0,51	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5419	5419	T	C	MI.14761	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	950	317	F	S	tTt/tCt	-0,57	0	0	possibly_damaging	0,48	neutral	0,5	neutral	1,95	neutral	-1,01	deleterious	-6,17	medium_impact	3,1	neutral	0,89	neutral	0,75	deleterious	2,53	19,63	0,13	0,4	neutral	0,43	disease	0,65	disease	0,55	disease	0,63	3	neutral	0,49	deleterious	0,51	NA	0	neutral	0,39	medium_impact	-0,77	medium_impact	0,21	medium_impact	1,47	0,13	0,8	8,65	9,18	N	0,39	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5419	5419	T	A	MI.14762	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	950	317	F	Y	tTt/tAt	-0,57	0	0	benign	0,35	neutral	1	neutral	1,95	neutral	-1,06	neutral	-1,91	medium_impact	2,55	neutral	0,88	neutral	0,93	neutral	1,23	11,91	0,25	0,45	neutral	0,35	neutral	0,5	neutral	0,37	neutral	0,47	1	neutral	0,35	deleterious	0,83	neutral	-3	neutral	0,36	medium_impact	-0,55	high_impact	1,87	medium_impact	1	0,2	0,8	8,65	9,18	N	0,31	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5419	5419	T	G	MI.14763	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	950	317	F	C	tTt/tGt	-0,57	0	0	possibly_damaging	0,82	neutral	0,19	neutral	1,91	deleterious	-3,35	deleterious	-6,14	medium_impact	2,9	neutral	0,87	neutral	0,46	deleterious	3,55	23,1	0,12	0,4	disease	0,87	disease	0,76	disease	0,56	disease	0,75	5	neutral	0,9	neutral	0,19	NA	0	deleterious	0,72	low_impact	-1,4	medium_impact	-0,14	medium_impact	1,3	0,11	0,8	8,65	9,18	N	0,38	N	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5420	5420	T	A	MI.14764	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	951	317	F	L	ttT/ttA	-0,11	0	0	benign	0	neutral	0,91	neutral	2,21	neutral	1,72	deleterious	-4,04	low_impact	0,86	neutral	0,97	neutral	0,96	neutral	1,18	11,66	0,27	0,45	neutral	0,5	neutral	0,3	neutral	0,33	neutral	0,29	4	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	0,77	medium_impact	-0,42	0,33	0,8	8,65	9,18	N	0,34	N	0,25	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5420	5420	T	G	MI.14765	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	951	317	F	L	ttT/ttG	-0,11	0	0	benign	0	neutral	0,91	neutral	2,21	neutral	1,72	deleterious	-4,04	low_impact	0,86	neutral	0,97	neutral	0,96	neutral	1,1	11,22	0,27	0,45	neutral	0,5	neutral	0,3	neutral	0,33	neutral	0,29	4	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	0,77	medium_impact	-0,42	0,33	0,8	8,65	9,18	N	0,33	N	0,25	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5421	5421	G	A	MI.14766	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	952	318	E	K	Gaa/Aaa	-6,35	0	0	benign	0,15	neutral	0,31	neutral	2,24	neutral	2,2	neutral	-1,74	neutral_impact	-0,67	neutral	0,81	neutral	0,83	deleterious	2,17	17,34	0,26	0,45	disease	0,58	neutral	0,18	neutral	0,24	neutral	0,3	4	neutral	0,64	deleterious	0,58	neutral	-6	neutral	0,26	medium_impact	-0,11	medium_impact	0,02	low_impact	-1,71	0,61	0,8	12,97	9,31	N	0,37	N	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5421	5421	G	C	MI.14767	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	952	318	E	Q	Gaa/Caa	-6,35	0	0	possibly_damaging	0,82	neutral	0,3	neutral	2,03	neutral	0,44	neutral	-1,27	neutral_impact	-0,32	neutral	0,85	neutral	0,93	neutral	1,64	14,06	0,57	0,65	disease	0,65	neutral	0,18	neutral	0,23	neutral	0,43	1	neutral	0,86	neutral	0,24	neutral	-3	deleterious	0,66	low_impact	-1,4	medium_impact	0	low_impact	-1,41	0,49	0,8	12,97	9,31	N	0,38	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5422	5422	A	G	MI.14768	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	953	318	E	G	gAa/gGa	-1,96	0	0	probably_damaging	0,92	neutral	0,33	neutral	1,96	neutral	-1,33	deleterious	-4,47	low_impact	1,15	neutral	0,86	neutral	0,82	deleterious	3,3	22,9	0,25	0,45	neutral	0,42	neutral	0,26	neutral	0,46	neutral	0,46	1	neutral	0,93	neutral	0,21	neutral	-2	deleterious	0,66	low_impact	-1,77	medium_impact	0,04	medium_impact	-0,18	0,31	0,8	12,97	9,31	N	0,36	N	0,6	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5422	5422	A	C	MI.14769	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	953	318	E	A	gAa/gCa	-1,96	0	0	possibly_damaging	0,82	neutral	0,51	neutral	1,99	neutral	-0,19	deleterious	-3,7	low_impact	1,29	neutral	0,9	neutral	0,43	deleterious	2,55	19,79	0,31	0,5	disease	0,66	neutral	0,23	neutral	0,42	disease	0,56	1	neutral	0,8	neutral	0,35	neutral	-3	deleterious	0,64	low_impact	-1,4	medium_impact	0,22	medium_impact	-0,06	0,36	0,8	12,97	9,31	N	0,37	N	0,39	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8381	8381	A	G	MI.1477	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	16	6	T	A	Act/Gct	-1,49	0	0	probably_damaging	0,97	neutral	0,07	neutral	1,51	deleterious	-4,04	deleterious	-4,48	medium_impact	2,99	neutral	0,99	neutral	0,53	deleterious	3,26	22,8	0,65309858	0,85	neutral	0,38	neutral	0,12	disease	0,64	neutral	0,2	6	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,69	low_impact	-2,19	medium_impact	-0,34	medium_impact	1,47	0,56	0,85	7,35	7,2	P	0,69	P	0,8	polymorphism	0,94	0,41	.	.	.	.	.	.	.	.	.	A8381G	MIDD/LVNC cardiomyopathy-assoc.	+	-	Reported	2
chrM	5422	5422	A	T	MI.14770	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	953	318	E	V	gAa/gTa	-1,96	0	0	probably_damaging	0,94	neutral	0,5	neutral	1,97	neutral	-0,68	deleterious	-4,6	low_impact	1,84	neutral	0,91	neutral	0,31	deleterious	3,3	22,9	0,22	0,45	disease	0,56	neutral	0,41	disease	0,52	disease	0,63	3	neutral	0,93	neutral	0,28	neutral	-2	deleterious	0,72	low_impact	-1,89	medium_impact	0,21	medium_impact	0,4	0,4	0,8	12,97	9,31	N	0,34	N	0,61	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5423	5423	A	T	MI.14771	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	954	318	E	D	gaA/gaT	0,13	0	0	possibly_damaging	0,8	neutral	0,21	neutral	1,97	neutral	-0,91	neutral	-1,96	low_impact	0,8	neutral	0,89	neutral	0,82	deleterious	2,64	20,4	0,42	0,55	disease	0,7	neutral	0,25	neutral	0,35	disease	0,57	1	neutral	0,88	neutral	0,21	neutral	-3	deleterious	0,66	low_impact	-1,35	medium_impact	-0,11	medium_impact	-0,47	0,54	0,8	12,97	9,31	P	0,56	P	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5423	5423	A	C	MI.14772	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	954	318	E	D	gaA/gaC	0,13	0	0	possibly_damaging	0,8	neutral	0,21	neutral	1,97	neutral	-0,91	neutral	-1,96	low_impact	0,8	neutral	0,89	neutral	0,82	deleterious	2,55	19,82	0,42	0,55	disease	0,7	neutral	0,25	neutral	0,35	disease	0,57	1	neutral	0,88	neutral	0,21	neutral	-3	deleterious	0,66	low_impact	-1,35	medium_impact	-0,11	medium_impact	-0,47	0,54	0,8	12,97	9,31	P	0,55	P	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5424	5424	C	G	MI.14773	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	955	319	H	D	Cat/Gat	-1,72	0	0	benign	0,03	neutral	0,2	neutral	1,98	neutral	-0,81	neutral	-1,1	low_impact	1,15	neutral	0,89	neutral	0,6	deleterious	2	16,2	0,31	0,45	disease	0,83	neutral	0,41	disease	0,57	disease	0,67	3	neutral	0,79	deleterious	0,59	neutral	-6	neutral	0,24	medium_impact	0,59	medium_impact	-0,13	medium_impact	-0,18	0,41	0,8	7,49	7,8	N	0,44	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5424	5424	C	T	MI.14774	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	955	319	H	Y	Cat/Tat	-1,72	0	0	benign	0	neutral	1	neutral	1,98	neutral	-0,77	neutral	-1,81	low_impact	1,15	neutral	0,98	neutral	0,92	deleterious	0,59	8,11	0,33	0,5	disease	0,56	neutral	0,35	neutral	0,37	disease	0,6	2	neutral	0	deleterious	1	neutral	-6	neutral	0,2	medium_impact	1,95	high_impact	1,87	medium_impact	-0,18	0,33	0,8	7,49	7,8	N	0,28	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5424	5424	C	A	MI.14775	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	955	319	H	N	Cat/Aat	-1,72	0	0	benign	0	neutral	0,33	neutral	2,07	neutral	1,16	neutral	1,43	neutral_impact	-1,1	neutral	0,97	neutral	0,97	neutral	-0,42	0,35	0,47	0,55	disease	0,59	neutral	0,17	neutral	0,31	neutral	0,28	4	neutral	0,67	deleterious	0,67	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,04	low_impact	-2,07	0,33	0,8	7,49	7,8	N	0,32	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5425	5425	A	G	MI.14776	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	956	319	H	R	cAt/cGt	-1,96	0	0	benign	0,04	neutral	0,34	neutral	2	neutral	-0,02	neutral	-1,33	neutral_impact	-0,02	neutral	0,91	neutral	0,66	neutral	0,98	10,57	0,33	0,5	disease	0,72	neutral	0,42	neutral	0,49	disease	0,65	3	neutral	0,63	deleterious	0,65	neutral	-6	neutral	0,25	medium_impact	0,47	medium_impact	0,05	low_impact	-1,16	0,12	0,8	7,49	7,8	N	0,39	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5425	5425	A	C	MI.14777	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	956	319	H	P	cAt/cCt	-1,96	0	0	benign	0,13	neutral	0,21	neutral	2,13	neutral	1,79	neutral	-2,35	neutral_impact	-0,78	neutral	0,87	neutral	0,95	neutral	-0,25	0,88	0,23	0,45	disease	0,66	disease	0,52	neutral	0,4	neutral	0,49	0	neutral	0,76	deleterious	0,54	neutral	-6	neutral	0,33	medium_impact	-0,04	medium_impact	-0,11	low_impact	-1,8	0,29	0,8	7,49	7,8	N	0,36	N	0,35	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5425	5425	A	T	MI.14778	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	956	319	H	L	cAt/cTt	-1,96	0	0	benign	0,03	neutral	0,66	neutral	2,05	neutral	0,99	deleterious	-2,98	neutral_impact	0,4	neutral	0,92	neutral	0,79	deleterious	0,66	8,58	0,31	0,45	disease	0,65	neutral	0,35	neutral	0,49	disease	0,61	2	neutral	0,29	deleterious	0,82	neutral	-6	neutral	0,17	medium_impact	0,59	medium_impact	0,37	medium_impact	-0,81	0,12	0,8	7,49	7,8	N	0,29	N	0,3	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5426	5426	T	A	MI.14779	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	957	319	H	Q	caT/caA	-1,96	0	0,02	benign	0,1	neutral	0,29	neutral	2,01	neutral	0,3	neutral	-0,88	neutral_impact	0,26	neutral	0,96	neutral	0,89	deleterious	0,48	7,29	0,39	0,5	disease	0,74	neutral	0,23	neutral	0,37	disease	0,57	1	neutral	0,67	deleterious	0,6	neutral	-6	neutral	0,24	medium_impact	0,08	medium_impact	-0,01	medium_impact	-0,93	0,59	0,8	7,49	7,8	N	0,44	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8381	8381	A	T	MI.1478	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	16	6	T	S	Act/Tct	-1,49	0	0	probably_damaging	0,97	neutral	0,08	neutral	1,5	deleterious	-4,36	deleterious	-3,66	medium_impact	2,99	neutral	0,99	neutral	0,46	deleterious	3,05	22,4	0,57868449	0,85	neutral	0,46	neutral	0,13	disease	0,63	neutral	0,21	6	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,71	low_impact	-2,19	medium_impact	-0,31	medium_impact	1,47	0,62	0,85	7,35	7,2	P	0,61	P	0,77	polymorphism	0,98	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5426	5426	T	G	MI.14780	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	957	319	H	Q	caT/caG	-1,96	0	0,02	benign	0,1	neutral	0,29	neutral	2,01	neutral	0,3	neutral	-0,88	neutral_impact	0,26	neutral	0,96	neutral	0,89	deleterious	0,37	6,39	0,39	0,5	disease	0,74	neutral	0,23	neutral	0,37	disease	0,57	1	neutral	0,67	deleterious	0,6	neutral	-6	neutral	0,24	medium_impact	0,08	medium_impact	-0,01	medium_impact	-0,93	0,59	0,8	7,49	7,8	N	0,43	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5427	5427	A	T	MI.14781	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	958	320	T	S	Aca/Tca	-6,58	0	0	benign	0,24	neutral	0,48	neutral	1,95	neutral	-0,57	neutral	-2,04	low_impact	1,79	neutral	0,8	neutral	0,97	deleterious	0,26	5,3	0,55	0,6	disease	0,56	neutral	0,18	neutral	0,28	neutral	0,32	4	neutral	0,42	deleterious	0,62	neutral	-6	deleterious	0,44	medium_impact	-0,34	medium_impact	0,19	medium_impact	0,36	0,57	0,8	8,93	8,99	N	0,37	N	0,33	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5427	5427	A	C	MI.14782	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	958	320	T	P	Aca/Cca	-6,58	0	0	possibly_damaging	0,64	neutral	0,26	neutral	1,91	neutral	-1,1	deleterious	-3,3	low_impact	1,23	neutral	0,9	neutral	0,97	deleterious	2,02	16,36	0,15	0,45	disease	0,83	disease	0,54	neutral	0,27	disease	0,59	2	neutral	0,77	neutral	0,31	neutral	-3	deleterious	0,73	low_impact	-1,03	medium_impact	-0,04	medium_impact	-0,11	0,31	0,8	8,93	8,99	N	0,45	N	0,47	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5427	5427	A	G	MI.14783	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	958	320	T	A	Aca/Gca	-6,58	0	0	benign	0,14	neutral	0,58	neutral	1,89	neutral	-1,44	deleterious	-2,88	medium_impact	2,62	neutral	0,93	neutral	0,77	neutral	1,63	13,99	0,39	0,5	neutral	0,4	neutral	0,26	neutral	0,46	neutral	0,46	1	neutral	0,32	deleterious	0,72	neutral	-3	neutral	0,28	medium_impact	-0,08	medium_impact	0,29	medium_impact	1,06	0,27	0,8	8,93	8,99	N	0,31	N	0,76	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5428	5428	C	A	MI.14784	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	959	320	T	K	aCa/aAa	-2,42	0	0	benign	0,34	neutral	0,4	neutral	2,07	neutral	0,54	deleterious	-2,87	low_impact	0,96	neutral	0,87	neutral	0,87	neutral	1,55	13,59	0,19	0,45	disease	0,77	neutral	0,42	neutral	0,38	disease	0,66	3	neutral	0,52	deleterious	0,53	neutral	-6	deleterious	0,52	medium_impact	-0,53	medium_impact	0,11	medium_impact	-0,34	0,37	0,8	8,93	8,99	N	0,35	N	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5428	5428	C	T	MI.14785	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	959	320	T	M	aCa/aTa	-2,42	0	0	benign	0,02	neutral	0,25	neutral	1,84	deleterious	-3,68	deleterious	-2,89	low_impact	1,8	neutral	0,98	neutral	0,96	neutral	0,91	10,14	0,24	0,45	neutral	0,35	neutral	0,29	neutral	0,35	neutral	0,45	1	neutral	0,74	deleterious	0,62	neutral	-6	neutral	0,14	medium_impact	0,75	medium_impact	-0,06	medium_impact	0,37	0,56	0,8	8,93	8,99	N	0,51	P	0,5	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5430	5430	A	G	MI.14786	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	961	321	K	E	Aaa/Gaa	-4,96	0	0	probably_damaging	1	neutral	0,49	neutral	1,82	neutral	-1,86	deleterious	-2,96	medium_impact	3,13	neutral	0,91	damaging	0,18	deleterious	4,17	23,8	0,32	0,5	disease	0,7	disease	0,7	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	0,2	medium_impact	1,49	0,36	0,8	NA	NA	N	0,34	N	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5430	5430	A	C	MI.14787	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	961	321	K	Q	Aaa/Caa	-4,96	0	0	probably_damaging	1	neutral	0,47	neutral	1,9	neutral	-0,76	deleterious	-2,93	low_impact	0,92	neutral	0,87	neutral	0,53	deleterious	2,38	18,69	0,52	0,6	disease	0,79	neutral	0,35	neutral	0,44	disease	0,65	3	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	0,18	medium_impact	-0,37	0,25	0,8	NA	NA	N	0,32	N	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5431	5431	A	T	MI.14788	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	962	321	K	M	aAa/aTa	-0,34	0	0	probably_damaging	1	neutral	0,27	neutral	1,79	neutral	-2,49	deleterious	-4,61	medium_impact	2,33	neutral	0,86	damaging	0,22	deleterious	3,93	23,5	0,19	0,45	disease	0,94	disease	0,52	neutral	0,46	disease	0,8	6	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,03	medium_impact	0,82	0,22	0,8	NA	NA	N	0,33	N	0,45	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5431	5431	A	C	MI.14789	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	962	321	K	T	aAa/aCa	-0,34	0	0	probably_damaging	1	neutral	0,56	neutral	1,85	neutral	-1,35	deleterious	-4,02	low_impact	1,34	neutral	0,88	neutral	0,46	deleterious	2,65	20,5	0,28	0,45	disease	0,77	neutral	0,47	neutral	0,42	disease	0,63	3	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,78	low_impact	-3,54	medium_impact	0,27	medium_impact	-0,02	0,15	0,8	NA	NA	N	0,29	N	0,81	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8381	8381	A	C	MI.1479	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	16	6	T	P	Act/Cct	-1,49	0	0	probably_damaging	0,99	neutral	1	neutral	2	deleterious	-6,14	deleterious	-5,55	low_impact	1,17	neutral	0,99	neutral	0,28	deleterious	3,31	22,9	0,50472207	0,85	disease	0,73	neutral	0,27	disease	0,61	neutral	0,17	7	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,78	low_impact	-2,65	high_impact	1,98	medium_impact	-0,1	0,57	0,85	7,35	7,2	N	0,33	N	0,89	polymorphism	0,75	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5432	5432	A	T	MI.14790	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	963	321	K	N	aaA/aaT	1,05	0	0	probably_damaging	1	neutral	0,45	neutral	1,97	neutral	-0,19	deleterious	-3,19	low_impact	1,82	neutral	0,87	neutral	0,89	deleterious	2,89	21,8	0,62	0,65	disease	0,68	neutral	0,49	neutral	0,41	neutral	0,49	0	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,78	low_impact	-3,54	medium_impact	0,16	medium_impact	0,39	0,3	0,8	NA	NA	N	0,36	N	0,69	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5432	5432	A	C	MI.14791	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	963	321	K	N	aaA/aaC	1,05	0	0	probably_damaging	1	neutral	0,45	neutral	1,97	neutral	-0,19	deleterious	-3,19	low_impact	1,82	neutral	0,87	neutral	0,89	deleterious	2,81	21,4	0,62	0,65	disease	0,68	neutral	0,49	neutral	0,41	neutral	0,49	0	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,78	low_impact	-3,54	medium_impact	0,16	medium_impact	0,39	0,3	0,8	NA	NA	N	0,35	N	0,69	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5433	5433	C	A	MI.14792	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	964	322	P	T	Ccc/Acc	-0,11	0	0	benign	0,06	neutral	0,5	neutral	2,01	neutral	0,11	neutral	-0,87	neutral_impact	0,01	neutral	0,89	neutral	0,96	deleterious	1,85	15,3	0,32	0,5	disease	0,5	neutral	0,26	neutral	0,29	neutral	0,25	5	neutral	0,45	deleterious	0,72	neutral	-6	neutral	0,28	medium_impact	0,3	medium_impact	0,21	low_impact	-1,14	0,38	0,8	16,71	9,25	N	0,39	N	0,22	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5433	5433	C	T	MI.14793	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	964	322	P	S	Ccc/Tcc	-0,11	0	0	benign	0,01	neutral	0,49	neutral	2,03	neutral	0,32	neutral	-0,53	neutral_impact	0,22	neutral	0,82	neutral	0,97	deleterious	2,13	17,05	0,39	0,5	neutral	0,42	neutral	0,29	neutral	0,3	neutral	0,46	1	neutral	0,5	deleterious	0,74	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,2	medium_impact	-0,96	0,14	0,8	16,71	9,25	N	0,35	N	0,55	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5433	5433	C	G	MI.14794	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	964	322	P	A	Ccc/Gcc	-0,11	0	0	benign	0,04	neutral	0,5	neutral	1,95	neutral	-0,72	neutral	-0,84	low_impact	1,18	neutral	0,88	neutral	0,72	neutral	1,31	12,31	0,47	0,55	neutral	0,34	neutral	0,22	neutral	0,46	neutral	0,41	2	neutral	0,46	deleterious	0,73	neutral	-6	neutral	0,23	medium_impact	0,47	medium_impact	0,21	medium_impact	-0,15	0,48	0,8	16,71	9,25	N	0,36	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5434	5434	C	A	MI.14795	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	965	322	P	H	cCc/cAc	-3,81	0	0	possibly_damaging	0,57	neutral	0,53	neutral	1,94	neutral	-0,94	neutral	-0,76	low_impact	1,14	neutral	0,82	neutral	0,97	deleterious	2,29	18,12	0,29	0,45	neutral	0,45	neutral	0,46	neutral	0,38	neutral	0,47	1	neutral	0,53	deleterious	0,48	neutral	-3	deleterious	0,58	medium_impact	-0,91	medium_impact	0,24	medium_impact	-0,19	0,31	0,8	16,71	9,25	N	0,3	N	0,3	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5434	5434	C	G	MI.14796	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	965	322	P	R	cCc/cGc	-3,81	0	0	benign	0,24	neutral	0,35	neutral	1,93	neutral	-1,33	neutral	-0,04	low_impact	1,48	neutral	0,89	neutral	0,67	deleterious	1,98	16,11	0,18	0,45	neutral	0,39	disease	0,61	neutral	0,47	neutral	0,48	0	neutral	0,58	deleterious	0,56	neutral	-6	deleterious	0,5	medium_impact	-0,34	medium_impact	0,06	medium_impact	0,1	0,34	0,8	16,71	9,25	N	0,37	N	0,64	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5434	5434	C	T	MI.14797	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	965	322	P	L	cCc/cTc	-3,81	0	0	benign	0	neutral	0,79	neutral	1,96	neutral	-0,63	neutral	-1,29	low_impact	1,28	neutral	0,84	neutral	0,88	deleterious	2,27	17,94	0,19	0,45	neutral	0,36	neutral	0,43	neutral	0,45	neutral	0,46	1	neutral	0,2	deleterious	0,9	neutral	-6	neutral	0,14	medium_impact	1,95	medium_impact	0,53	medium_impact	-0,07	0,61	0,8	16,71	9,25	N	0,28	N	0,9	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5436	5436	A	T	MI.14798	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	967	323	T	S	Acc/Tcc	-5,66	0	0	benign	0,12	neutral	0,55	neutral	1,96	neutral	-0,25	neutral	-1,1	low_impact	0,82	neutral	0,87	neutral	0,86	deleterious	2,43	19	0,45	0,55	neutral	0,38	neutral	0,23	neutral	0,28	neutral	0,44	1	neutral	0,36	deleterious	0,72	neutral	-6	neutral	0,42	medium_impact	-0,01	medium_impact	0,26	medium_impact	-0,45	0,49	0,8	16,43	9,29	N	0,35	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5436	5436	A	C	MI.14799	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	967	323	T	P	Acc/Ccc	-5,66	0	0	benign	0,36	neutral	0,23	neutral	1,84	neutral	-1,66	neutral	-2,5	low_impact	1,55	neutral	0,88	neutral	0,79	deleterious	2,86	21,7	0,12	0,4	disease	0,66	disease	0,71	neutral	0,28	disease	0,54	1	neutral	0,73	neutral	0,44	neutral	-6	deleterious	0,66	medium_impact	-0,57	medium_impact	-0,08	medium_impact	0,16	0,35	0,8	16,43	9,29	N	0,39	N	0,73	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8596	8596	A	G	MI.148	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	70	24	I	V	Att/Gtt	-7,51	0	0	probably_damaging	0,93	neutral	0,34	neutral	4,15	neutral	-1,03	neutral	-0,7	low_impact	1,25	neutral	0,94	neutral	0,97	neutral	1,59	13,81	0,65	0,7	neutral	0,34	neutral	0,2	neutral	0,35	neutral	0,38	2	neutral	0,94	neutral	0,21	neutral	-2	deleterious	0,6	low_impact	-1,82	medium_impact	0,13	medium_impact	-0,03	0,51	0,9	18,14	17,22	N	0,42	N	0,04	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8382	8382	C	A	MI.1480	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	17	6	T	N	aCt/aAt	3,83	0,99	0	probably_damaging	0,99	neutral	0,05	neutral	1,48	deleterious	-5,68	deleterious	-4,66	medium_impact	3,34	neutral	0,99	neutral	0,43	deleterious	3,5	23,1	0,61963595	0,85	disease	0,69	neutral	0,23	disease	0,68	neutral	0,21	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,76	low_impact	-2,65	medium_impact	-0,43	medium_impact	1,77	0,73	0,85	7,35	7,2	P	0,69	P	0,85	disease_causing	0,96	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5436	5436	A	G	MI.14800	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	967	323	T	A	Acc/Gcc	-5,66	0	0	benign	0,07	neutral	0,51	neutral	1,83	neutral	-1,92	neutral	-1,3	medium_impact	2,34	neutral	0,92	neutral	0,89	deleterious	2,56	19,88	0,27	0,45	neutral	0,35	neutral	0,29	neutral	0,43	neutral	0,45	1	neutral	0,43	deleterious	0,72	neutral	-3	neutral	0,35	medium_impact	0,23	medium_impact	0,22	medium_impact	0,83	0,24	0,8	16,43	9,29	N	0,35	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5437	5437	C	T	MI.14801	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	968	323	T	I	aCc/aTc	-1,72	0	0	benign	0,08	neutral	0,48	neutral	1,85	neutral	-1,56	neutral	-0,68	low_impact	1,07	neutral	0,9	neutral	0,94	deleterious	2,5	19,44	0,19	0,45	neutral	0,42	neutral	0,45	neutral	0,33	neutral	0,46	1	neutral	0,46	deleterious	0,7	neutral	-6	neutral	0,4	medium_impact	0,17	medium_impact	0,19	medium_impact	-0,24	0,34	0,8	16,43	9,29	N	0,37	N	0,27	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5437	5437	C	A	MI.14802	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	968	323	T	N	aCc/aAc	-1,72	0	0	benign	0,36	neutral	0,39	neutral	1,95	neutral	-0,34	neutral	-2,27	low_impact	1,58	neutral	0,79	neutral	0,95	deleterious	2,09	16,78	0,4	0,5	neutral	0,33	neutral	0,42	neutral	0,3	neutral	0,47	1	neutral	0,54	deleterious	0,52	neutral	-6	deleterious	0,52	medium_impact	-0,57	medium_impact	0,1	medium_impact	0,19	0,36	0,8	16,43	9,29	N	0,37	N	0,19	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5437	5437	C	G	MI.14803	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	968	323	T	S	aCc/aGc	-1,72	0	0	benign	0,12	neutral	0,55	neutral	1,96	neutral	-0,25	neutral	-1,1	low_impact	0,82	neutral	0,87	neutral	0,86	deleterious	2,1	16,83	0,45	0,55	neutral	0,38	neutral	0,23	neutral	0,28	neutral	0,44	1	neutral	0,36	deleterious	0,72	neutral	-6	neutral	0,42	medium_impact	-0,01	medium_impact	0,26	medium_impact	-0,45	0,49	0,8	16,43	9,29	N	0,34	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5439	5439	C	G	MI.14804	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	970	324	P	A	Cca/Gca	-4,27	0	0	benign	0	neutral	0,52	neutral	2,04	neutral	0,81	deleterious	-3,12	neutral_impact	0,62	neutral	0,86	neutral	0,89	neutral	1,19	11,7	0,23	0,45	disease	0,86	neutral	0,09	neutral	0,43	neutral	0,36	3	neutral	0,47	deleterious	0,76	neutral	-6	deleterious	0,7	medium_impact	1,95	medium_impact	0,23	medium_impact	-0,62	0,56	0,8	8,93	8,2	N	0,36	N	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5439	5439	C	A	MI.14805	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	970	324	P	T	Cca/Aca	-4,27	0	0	benign	0,01	neutral	0,46	neutral	2,08	neutral	1,33	neutral	-2,34	neutral_impact	-0,8	neutral	0,83	neutral	0,98	deleterious	1,85	15,29	0,26	0,45	disease	0,84	neutral	0,08	neutral	0,18	neutral	0,36	3	neutral	0,53	deleterious	0,73	neutral	-6	deleterious	0,69	medium_impact	1,03	medium_impact	0,17	low_impact	-1,82	0,46	0,8	8,93	8,2	N	0,45	N	0,19	polymorphism	1	0,02	rs879127743	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5439	5439	C	T	MI.14806	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	970	324	P	S	Cca/Tca	-4,27	0	0	benign	0,02	neutral	0,47	neutral	2,03	neutral	0,7	deleterious	-2,84	neutral_impact	0,45	neutral	0,73	neutral	0,91	deleterious	2,25	17,84	0,26	0,45	disease	0,88	neutral	0,14	neutral	0,23	neutral	0,38	2	neutral	0,51	deleterious	0,73	neutral	-6	deleterious	0,71	medium_impact	0,75	medium_impact	0,18	medium_impact	-0,77	0,23	0,8	8,93	8,2	N	0,35	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5440	5440	C	G	MI.14807	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	971	324	P	R	cCa/cGa	-1,03	0	0	benign	0,04	neutral	0,35	neutral	1,96	neutral	-1,71	deleterious	-3,61	low_impact	1,06	neutral	0,89	neutral	0,55	deleterious	2,06	16,58	0,18	0,45	disease	0,9	neutral	0,41	disease	0,62	disease	0,67	3	neutral	0,62	deleterious	0,66	neutral	-6	deleterious	0,79	medium_impact	0,47	medium_impact	0,06	medium_impact	-0,25	0,53	0,8	8,93	8,2	N	0,4	N	0,72	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5440	5440	C	A	MI.14808	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	971	324	P	Q	cCa/cAa	-1,03	0	0	benign	0,08	neutral	0,29	neutral	1,98	neutral	-0,75	deleterious	-3,15	low_impact	1,06	neutral	0,85	neutral	0,58	deleterious	2,7	20,8	0,21	0,45	disease	0,9	neutral	0,26	neutral	0,36	disease	0,58	2	neutral	0,68	deleterious	0,61	neutral	-6	deleterious	0,75	medium_impact	0,17	medium_impact	-0,01	medium_impact	-0,25	0,36	0,8	8,93	8,2	N	0,38	N	0,72	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5440	5440	C	T	MI.14809	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	971	324	P	L	cCa/cTa	-1,03	0	0	benign	0	neutral	0,74	neutral	2,28	neutral	2,69	deleterious	-3,8	neutral_impact	-0,46	neutral	0,93	neutral	0,96	deleterious	2,21	17,59	0,25	0,45	disease	0,83	neutral	0,19	neutral	0,44	neutral	0,44	1	neutral	0,26	deleterious	0,87	neutral	-6	deleterious	0,73	medium_impact	1,95	medium_impact	0,46	low_impact	-1,53	0,51	0,8	8,93	8,2	N	0,37	N	0,24	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8382	8382	C	T	MI.1481	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	17	6	T	I	aCt/aTt	3,83	0,99	0	probably_damaging	0,99	neutral	0,2	neutral	1,52	deleterious	-5,39	deleterious	-4,99	medium_impact	1,95	neutral	0,98	neutral	0,53	deleterious	3,89	23,5	0,57868449	0,85	disease	0,68	neutral	0,22	disease	0,55	neutral	0,17	7	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,77	low_impact	-2,65	medium_impact	-0,05	medium_impact	0,57	0,63	0,85	7,35	7,2	P	0,68	P	0,76	disease_causing	0,96	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5442	5442	T	A	MI.14810	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	973	325	F	I	Ttc/Atc	-11,21	0	0,01	benign	0,01	neutral	0,64	neutral	2,1	neutral	1,22	neutral	0,28	neutral_impact	-0,66	neutral	0,91	neutral	0,95	deleterious	2,89	21,8	0,17	0,45	neutral	0,4	neutral	0,1	neutral	0,47	neutral	0,31	4	neutral	0,35	deleterious	0,82	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,35	low_impact	-1,7	0,35	0,8	NA	NA	N	0,29	N	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5442	5442	T	G	MI.14811	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	973	325	F	V	Ttc/Gtc	-11,21	0	0,01	benign	0,01	neutral	0,55	neutral	2,01	neutral	0,15	neutral	-0,41	neutral_impact	0,11	neutral	0,89	neutral	0,77	deleterious	2,91	21,9	0,17	0,45	neutral	0,37	neutral	0,26	disease	0,59	neutral	0,46	1	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,26	low_impact	-1,05	0,28	0,8	NA	NA	N	0,33	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5442	5442	T	C	MI.14812	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	973	325	F	L	Ttc/Ctc	-11,21	0	0,01	benign	0	neutral	0,96	neutral	2,25	neutral	2,21	neutral	1,48	neutral_impact	-1,74	neutral	0,99	neutral	0,99	neutral	-0,1	1,7	0,17	0,45	neutral	0,35	neutral	0,07	neutral	0,38	neutral	0,19	6	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,1	medium_impact	1,95	medium_impact	0,98	low_impact	-2,61	0,24	0,8	NA	NA	N	0,29	N	0,01	polymorphism	1	0,01	rs3020601	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5443	5443	T	A	MI.14813	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	974	325	F	Y	tTc/tAc	-5,66	0	0	benign	0,02	neutral	1	neutral	1,99	neutral	-0,24	neutral	-0,92	neutral_impact	0	neutral	0,88	neutral	0,83	neutral	1,67	14,22	0,18	0,45	disease	0,76	neutral	0,18	neutral	0,48	neutral	0,44	1	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,25	medium_impact	0,75	high_impact	1,87	low_impact	-1,14	0,33	0,8	NA	NA	N	0,3	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5443	5443	T	C	MI.14814	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	974	325	F	S	tTc/tCc	-5,66	0	0	benign	0,02	neutral	0,59	neutral	1,99	neutral	-0,16	neutral	-2,3	neutral_impact	0,11	neutral	0,79	neutral	0,95	deleterious	3,04	22,3	0,11	0,4	disease	0,7	neutral	0,23	disease	0,54	disease	0,55	1	neutral	0,37	deleterious	0,79	neutral	-6	neutral	0,31	medium_impact	0,75	medium_impact	0,3	low_impact	-1,05	0,19	0,8	NA	NA	N	0,28	N	0,72	polymorphism	1	0,06	rs878943513	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5443	5443	T	G	MI.14815	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	974	325	F	C	tTc/tGc	-5,66	0	0	benign	0,19	neutral	0,17	neutral	1,94	neutral	-1,9	neutral	-1	neutral_impact	-0,55	neutral	0,9	neutral	0,76	deleterious	3,04	22,3	0,13	0,4	disease	0,89	neutral	0,42	disease	0,64	disease	0,66	3	neutral	0,8	deleterious	0,49	neutral	-6	deleterious	0,53	medium_impact	-0,22	medium_impact	-0,17	low_impact	-1,61	0,18	0,8	NA	NA	N	0,43	N	0,63	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5444	5444	C	A	MI.14816	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	975	325	F	L	ttC/ttA	-0,34	0	0	benign	0	neutral	0,96	neutral	2,25	neutral	2,21	neutral	1,48	neutral_impact	-1,74	neutral	0,99	neutral	0,99	deleterious	0,53	7,65	0,17	0,45	neutral	0,35	neutral	0,07	neutral	0,38	neutral	0,19	6	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,1	medium_impact	1,95	medium_impact	0,98	low_impact	-2,61	0,24	0,8	NA	NA	N	0,4	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5444	5444	C	G	MI.14817	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	975	325	F	L	ttC/ttG	-0,34	0	0	benign	0	neutral	0,96	neutral	2,25	neutral	2,21	neutral	1,48	neutral_impact	-1,74	neutral	0,99	neutral	0,99	deleterious	0,21	4,79	0,17	0,45	neutral	0,35	neutral	0,07	neutral	0,38	neutral	0,19	6	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,1	medium_impact	1,95	medium_impact	0,98	low_impact	-2,61	0,24	0,8	NA	NA	N	0,4	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5445	5445	C	T	MI.14818	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	976	326	L	F	Ctc/Ttc	-9,36	0	0	benign	0,16	neutral	0,71	neutral	1,45	deleterious	-3,47	deleterious	-3,07	medium_impact	3,01	neutral	0,94	neutral	0,63	deleterious	4	23,6	0,24	0,45	disease	0,65	neutral	0,4	neutral	0,42	disease	0,62	2	neutral	0,17	deleterious	0,78	neutral	-3	deleterious	0,54	medium_impact	-0,14	medium_impact	0,42	medium_impact	1,39	0,48	0,8	NA	NA	N	0,27	N	0,24	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5445	5445	C	G	MI.14819	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	976	326	L	V	Ctc/Gtc	-9,36	0	0	benign	0,03	neutral	0,46	neutral	1,51	neutral	-2,57	neutral	-1,91	medium_impact	2,16	neutral	0,91	neutral	0,76	deleterious	3,32	22,9	0,22	0,45	disease	0,55	neutral	0,26	neutral	0,39	disease	0,55	1	neutral	0,51	deleterious	0,72	neutral	-3	neutral	0,28	medium_impact	0,59	medium_impact	0,17	medium_impact	0,67	0,29	0,8	NA	NA	N	0,4	N	0,45	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8382	8382	C	G	MI.1482	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	17	6	T	S	aCt/aGt	3,83	0,99	0	probably_damaging	0,97	neutral	0,08	neutral	1,5	deleterious	-4,36	deleterious	-3,66	medium_impact	2,99	neutral	0,99	neutral	0,46	deleterious	3,43	23	0,57868449	0,85	neutral	0,46	neutral	0,13	disease	0,63	neutral	0,21	6	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,71	low_impact	-2,19	medium_impact	-0,31	medium_impact	1,47	0,62	0,85	7,35	7,2	P	0,71	P	0,77	disease_causing	0,69	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5445	5445	C	A	MI.14820	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	976	326	L	I	Ctc/Atc	-9,36	0	0	benign	0	neutral	0,49	neutral	1,6	neutral	-1,74	neutral	-1,24	low_impact	1,64	neutral	0,94	neutral	0,94	deleterious	2,47	19,29	0,23	0,45	disease	0,53	neutral	0,07	neutral	0,33	neutral	0,26	5	neutral	0,51	deleterious	0,75	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,2	medium_impact	0,24	0,38	0,8	NA	NA	N	0,42	N	0,05	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5446	5446	T	G	MI.14821	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	977	326	L	R	cTc/cGc	-2,65	0	0	possibly_damaging	0,54	neutral	0,3	neutral	1,4	deleterious	-5,6	deleterious	-4,75	medium_impact	3,36	neutral	0,84	neutral	0,43	deleterious	4,26	23,9	0,1	0,4	disease	0,88	disease	0,76	disease	0,7	disease	0,78	6	neutral	0,69	neutral	0,38	NA	0	deleterious	0,77	medium_impact	-0,86	medium_impact	0	medium_impact	1,68	0,25	0,8	NA	NA	N	0,35	N	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5446	5446	T	A	MI.14822	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	977	326	L	H	cTc/cAc	-2,65	0	0	possibly_damaging	0,63	neutral	0,48	neutral	1,4	deleterious	-5,14	deleterious	-5,61	medium_impact	3,36	neutral	0,84	neutral	0,53	deleterious	4,24	23,9	0,12	0,4	disease	0,91	disease	0,63	disease	0,66	disease	0,75	5	neutral	0,61	neutral	0,43	NA	0	deleterious	0,75	low_impact	-1,01	medium_impact	0,19	medium_impact	1,68	0,28	0,8	NA	NA	N	0,33	N	0,85	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5446	5446	T	C	MI.14823	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	977	326	L	P	cTc/cCc	-2,65	0	0	possibly_damaging	0,54	neutral	0,22	neutral	1,4	deleterious	-5,5	deleterious	-5,57	medium_impact	2,12	neutral	0,86	neutral	0,35	deleterious	3,98	23,6	0,09	0,35	disease	0,8	disease	0,74	disease	0,59	disease	0,73	5	neutral	0,77	neutral	0,34	NA	0	deleterious	0,76	medium_impact	-0,86	medium_impact	-0,1	medium_impact	0,64	0,24	0,8	NA	NA	N	0,32	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5448	5448	C	T	MI.14824	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	979	327	P	S	Ccc/Tcc	-6,35	0	0	benign	0,01	neutral	0,73	neutral	2,23	neutral	1,69	deleterious	-3,19	neutral_impact	0,56	neutral	0,91	neutral	0,98	deleterious	2,28	18,01	0,32	0,5	disease	0,51	neutral	0,15	neutral	0,37	neutral	0,27	5	neutral	0,24	deleterious	0,86	neutral	-6	neutral	0,16	medium_impact	1,03	medium_impact	0,45	medium_impact	-0,67	0,25	0,8	NA	NA	N	0,39	N	0,44	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5448	5448	C	G	MI.14825	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	979	327	P	A	Ccc/Gcc	-6,35	0	0	benign	0,08	neutral	0,53	neutral	2,21	neutral	1,61	deleterious	-3,52	neutral_impact	0,6	neutral	0,8	neutral	0,98	neutral	1,77	14,81	0,25	0,45	neutral	0,49	neutral	0,05	neutral	0,49	neutral	0,21	6	neutral	0,4	deleterious	0,73	neutral	-6	neutral	0,29	medium_impact	0,17	medium_impact	0,24	medium_impact	-0,64	0,61	0,8	NA	NA	N	0,39	N	0,48	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5448	5448	C	A	MI.14826	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	979	327	P	T	Ccc/Acc	-6,35	0	0	benign	0,12	neutral	0,6	neutral	2,04	neutral	0,45	deleterious	-3,93	neutral_impact	0,76	neutral	0,84	neutral	0,89	deleterious	2,56	19,86	0,28	0,45	neutral	0,4	neutral	0,16	neutral	0,35	neutral	0,31	4	neutral	0,3	deleterious	0,74	neutral	-6	neutral	0,36	medium_impact	-0,01	medium_impact	0,31	medium_impact	-0,51	0,61	0,8	NA	NA	N	0,34	N	0,66	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5449	5449	C	A	MI.14827	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	980	327	P	H	cCc/cAc	-0,57	0	0	possibly_damaging	0,75	neutral	0,41	neutral	1,9	neutral	-2,66	deleterious	-5,33	medium_impact	2,96	neutral	0,89	neutral	0,39	deleterious	4,13	23,8	0,2	0,45	disease	0,6	neutral	0,43	disease	0,64	disease	0,65	3	neutral	0,75	neutral	0,33	NA	0	deleterious	0,65	low_impact	-1,23	medium_impact	0,12	medium_impact	1,35	0,41	0,8	NA	NA	N	0,42	N	0,85	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5449	5449	C	T	MI.14828	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	980	327	P	L	cCc/cTc	-0,57	0	0	benign	0,31	neutral	1	neutral	1,93	neutral	-1,33	deleterious	-5,92	medium_impact	2,15	neutral	0,9	neutral	0,55	deleterious	4,44	24,2	0,21	0,45	disease	0,51	neutral	0,4	neutral	0,33	neutral	0,37	3	neutral	0,31	deleterious	0,85	neutral	-3	deleterious	0,47	medium_impact	-0,48	high_impact	1,87	medium_impact	0,67	0,52	0,8	NA	NA	N	0,28	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5449	5449	C	G	MI.14829	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	980	327	P	R	cCc/cGc	-0,57	0	0	possibly_damaging	0,5	neutral	0,31	neutral	1,92	neutral	-1,6	deleterious	-5,18	medium_impact	2,96	neutral	0,89	neutral	0,38	deleterious	3,66	23,2	0,19	0,45	disease	0,56	disease	0,55	disease	0,68	disease	0,72	4	neutral	0,66	neutral	0,41	NA	0	deleterious	0,58	medium_impact	-0,8	medium_impact	0,02	medium_impact	1,35	0,5	0,8	NA	NA	N	0,41	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8384	8384	A	G	MI.1483	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	19	7	T	A	Acc/Gcc	-2,42	0	0	benign	0	neutral	0,88	neutral	2,2	neutral	-0,48	neutral	-0,48	low_impact	1,28	neutral	1	neutral	0,81	deleterious	0,89	9,99	0,55484047	0,85	neutral	0,22	neutral	0,09	neutral	0,48	neutral	0,12	8	neutral	0,12	deleterious	0,94	neutral	-6	neutral	0,14	high_impact	2,09	medium_impact	0,78	medium_impact	0	0,45	0,85	5,88	6,93	N	0,34	N	0,15	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5451	5451	A	C	MI.14830	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	982	328	T	P	Aca/Cca	-5,89	0	0	benign	0	neutral	0,26	neutral	1,83	neutral	-2,15	neutral	2,73	neutral_impact	-0,58	neutral	0,97	neutral	0,97	deleterious	0,81	9,53	0,11	0,4	disease	0,85	neutral	0,27	neutral	0,4	disease	0,6	2	neutral	0,74	deleterious	0,63	neutral	-6	neutral	0,22	medium_impact	1,95	medium_impact	-0,04	low_impact	-1,63	0,32	0,8	1,15	7,37	N	0,36	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5451	5451	A	G	MI.14831	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	982	328	T	A	Aca/Gca	-5,89	0	0	benign	0,01	neutral	0,61	neutral	1,87	neutral	-1,32	neutral	-0,94	low_impact	0,88	neutral	0,94	neutral	0,87	deleterious	2,09	16,81	0,28	0,45	neutral	0,48	neutral	0,12	neutral	0,33	neutral	0,26	5	neutral	0,38	deleterious	0,8	neutral	-6	neutral	0,15	medium_impact	1,03	medium_impact	0,32	medium_impact	-0,4	0,15	0,8	1,15	7,37	N	0,34	N	0,55	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5451	5451	A	T	MI.14832	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	982	328	T	S	Aca/Tca	-5,89	0	0	benign	0,02	neutral	0,65	neutral	1,84	neutral	-1,95	neutral	-0,92	low_impact	1,05	neutral	0,9	neutral	0,93	deleterious	2	16,23	0,39	0,5	disease	0,54	neutral	0,19	neutral	0,33	neutral	0,33	3	neutral	0,32	deleterious	0,82	neutral	-6	neutral	0,19	medium_impact	0,75	medium_impact	0,36	medium_impact	-0,26	0,5	0,8	1,15	7,37	N	0,34	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5452	5452	C	A	MI.14833	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	983	328	T	K	aCa/aAa	-2,42	0	0	benign	0,02	neutral	0,31	neutral	1,8	deleterious	-3,97	neutral	-1,64	medium_impact	2,2	neutral	0,85	neutral	0,43	deleterious	4,33	24	0,13	0,4	disease	0,87	disease	0,52	disease	0,73	disease	0,75	5	neutral	0,68	deleterious	0,65	neutral	-3	neutral	0,31	medium_impact	0,75	medium_impact	0,02	medium_impact	0,71	0,36	0,8	1,15	7,37	N	0,34	N	0,84	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5452	5452	C	T	MI.14834	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	983	328	T	M	aCa/aTa	-2,42	0	0	benign	0,06	neutral	0,33	neutral	1,91	neutral	-0,84	neutral	-2,06	low_impact	1,3	neutral	0,91	neutral	0,78	deleterious	2,97	22,1	0,15	0,45	disease	0,8	neutral	0,24	neutral	0,43	disease	0,57	1	neutral	0,64	deleterious	0,64	neutral	-6	neutral	0,36	medium_impact	0,3	medium_impact	0,04	medium_impact	-0,05	0,46	0,8	1,15	7,37	N	0,49	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	CPD	0,15	C5452T	Progressive Encephalomyopathy	+	-	Reported	1
chrM	5454	5454	C	T	MI.14835	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	985	329	L	F	Ctc/Ttc	-7,74	0	0	probably_damaging	0,98	neutral	0,76	neutral	1,58	neutral	-2,67	deleterious	-2,87	medium_impact	1,99	neutral	0,93	neutral	0,8	deleterious	3,93	23,5	0,24	0,45	disease	0,65	neutral	0,27	neutral	0,47	disease	0,56	1	neutral	0,98	neutral	0,39	deleterious	1	deleterious	0,71	low_impact	-2,34	medium_impact	0,49	medium_impact	0,53	0,61	0,8	NA	NA	N	0,31	N	0,71	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5454	5454	C	G	MI.14836	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	985	329	L	V	Ctc/Gtc	-7,74	0	0	possibly_damaging	0,89	neutral	0,54	neutral	1,6	neutral	-2,34	neutral	-2,22	medium_impact	2,42	neutral	0,91	neutral	0,68	deleterious	3,35	22,9	0,23	0,45	disease	0,51	neutral	0,21	neutral	0,43	neutral	0,3	4	neutral	0,88	neutral	0,33	NA	0	deleterious	0,66	low_impact	-1,63	medium_impact	0,25	medium_impact	0,89	0,4	0,8	NA	NA	N	0,33	N	0,41	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5454	5454	C	A	MI.14837	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	985	329	L	I	Ctc/Atc	-7,74	0	0	probably_damaging	0,93	neutral	0,48	neutral	1,57	neutral	-2,71	neutral	-1,47	low_impact	1,57	neutral	0,93	neutral	0,86	deleterious	2,92	21,9	0,22	0,45	disease	0,57	neutral	0,12	neutral	0,35	neutral	0,3	4	neutral	0,92	neutral	0,28	neutral	-2	deleterious	0,65	low_impact	-1,83	medium_impact	0,19	medium_impact	0,18	0,55	0,8	NA	NA	N	0,36	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5455	5455	T	G	MI.14838	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	986	329	L	R	cTc/cGc	-3,81	0	0	probably_damaging	0,98	neutral	0,41	neutral	1,5	deleterious	-5,4	deleterious	-4,92	medium_impact	3,31	neutral	0,81	neutral	0,43	deleterious	4,23	23,9	0,09	0,35	disease	0,88	disease	0,69	disease	0,76	disease	0,79	6	neutral	0,98	neutral	0,22	deleterious	1	deleterious	0,82	low_impact	-2,34	medium_impact	0,12	medium_impact	1,64	0,31	0,8	NA	NA	N	0,35	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5455	5455	T	A	MI.14839	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	986	329	L	H	cTc/cAc	-3,81	0	0	probably_damaging	0,99	neutral	0,55	neutral	1,49	deleterious	-5,93	deleterious	-5,7	medium_impact	3,31	neutral	0,82	neutral	0,48	deleterious	4,34	24	0,13	0,4	disease	0,91	disease	0,55	disease	0,73	disease	0,78	6	deleterious	0,98	neutral	0,28	deleterious	1	deleterious	0,78	low_impact	-2,62	medium_impact	0,26	medium_impact	1,64	0,23	0,8	NA	NA	N	0,28	N	0,85	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8384	8384	A	C	MI.1484	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	19	7	T	P	Acc/Ccc	-2,42	0	0	benign	0,05	neutral	0,25	neutral	1,91	neutral	-2,72	deleterious	-2,5	medium_impact	2,33	neutral	0,99	neutral	0,42	deleterious	1,99	16,15	0,24683078	0,85	disease	0,56	neutral	0,31	disease	0,54	neutral	0,2	6	neutral	0,73	deleterious	0,6	neutral	-3	neutral	0,22	medium_impact	0,46	medium_impact	0,02	medium_impact	0,9	0,58	0,85	5,88	6,93	N	0,5	N	0,24	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5455	5455	T	C	MI.14840	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	986	329	L	P	cTc/cCc	-3,81	0	0	probably_damaging	0,99	neutral	0,26	neutral	1,56	neutral	-2,98	deleterious	-5,82	medium_impact	2,62	neutral	0,87	neutral	0,5	deleterious	3,99	23,6	0,11	0,4	disease	0,91	disease	0,65	disease	0,63	disease	0,75	5	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,82	low_impact	-2,62	medium_impact	-0,04	medium_impact	1,06	0,29	0,8	NA	NA	N	0,36	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5457	5457	A	C	MI.14841	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	988	330	I	L	Atc/Ctc	-2,65	0	0	benign	0	neutral	1	neutral	1,98	neutral	-0,12	neutral	-1,26	low_impact	1,12	neutral	0,84	neutral	0,89	neutral	0,93	10,23	0,18	0,45	disease	0,53	neutral	0,35	neutral	0,26	neutral	0,45	1	neutral	0	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,95	high_impact	1,87	medium_impact	-0,2	0,33	0,8	NA	NA	N	0,26	N	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5457	5457	A	G	MI.14842	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	988	330	I	V	Atc/Gtc	-2,65	0	0	benign	0,01	neutral	0,42	neutral	1,92	neutral	-0,73	neutral	-0,7	low_impact	1,3	neutral	0,92	neutral	0,98	deleterious	0,23	4,95	0,21	0,45	neutral	0,48	neutral	0,17	neutral	0,37	neutral	0,31	4	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,14	medium_impact	1,03	medium_impact	0,13	medium_impact	-0,05	0,16	0,8	NA	NA	N	0,43	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5457	5457	A	T	MI.14843	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	988	330	I	F	Atc/Ttc	-2,65	0	0	benign	0,08	neutral	0,7	neutral	1,84	neutral	-1,84	deleterious	-2,51	medium_impact	2,15	neutral	0,95	neutral	0,78	deleterious	3,51	23,1	0,12	0,4	disease	0,51	disease	0,51	neutral	0,39	neutral	0,49	0	neutral	0,21	deleterious	0,81	neutral	-3	neutral	0,31	medium_impact	0,17	medium_impact	0,41	medium_impact	0,67	0,32	0,8	NA	NA	N	0,24	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5458	5458	T	A	MI.14844	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	989	330	I	N	aTc/aAc	-1,26	0	0	benign	0,32	neutral	0,23	neutral	1,82	neutral	-2,39	deleterious	-5,47	medium_impact	1,98	neutral	0,89	neutral	0,42	deleterious	4,35	24,1	0,13	0,4	disease	0,83	disease	0,69	disease	0,6	disease	0,74	5	neutral	0,72	neutral	0,46	neutral	-3	deleterious	0,54	medium_impact	-0,5	medium_impact	-0,08	medium_impact	0,52	0,22	0,8	NA	NA	N	0,41	N	0,57	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5458	5458	T	C	MI.14845	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	989	330	I	T	aTc/aCc	-1,26	0	0	benign	0,08	neutral	0,6	neutral	1,99	neutral	-0,1	deleterious	-3,56	neutral_impact	0,38	neutral	0,92	neutral	0,95	deleterious	0,3	5,68	0,18	0,45	disease	0,52	neutral	0,13	neutral	0,31	neutral	0,2	6	neutral	0,32	deleterious	0,76	neutral	-6	neutral	0,28	medium_impact	0,17	medium_impact	0,31	medium_impact	-0,83	0,27	0,8	NA	NA	N	0,38	N	0,05	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5458	5458	T	G	MI.14846	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	989	330	I	S	aTc/aGc	-1,26	0	0	benign	0,1	neutral	0,47	neutral	2	neutral	-0,02	deleterious	-4,43	low_impact	1,25	neutral	0,87	neutral	0,69	deleterious	4,06	23,7	0,1	0,4	disease	0,6	disease	0,56	neutral	0,42	disease	0,51	0	neutral	0,46	deleterious	0,69	neutral	-6	neutral	0,33	medium_impact	0,08	medium_impact	0,18	medium_impact	-0,09	0,23	0,8	NA	NA	N	0,31	N	0,4	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5459	5459	C	A	MI.14847	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	990	330	I	M	atC/atA	-0,57	0	0	benign	0	neutral	0,38	neutral	1,9	neutral	-0,93	neutral	-1,93	low_impact	1,91	neutral	0,93	neutral	0,78	deleterious	2,47	19,29	0,21	0,45	neutral	0,35	neutral	0,29	neutral	0,32	neutral	0,46	1	neutral	0,62	deleterious	0,69	neutral	-6	neutral	0,13	medium_impact	1,95	medium_impact	0,09	medium_impact	0,46	0,35	0,8	NA	NA	N	0,41	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5459	5459	C	G	MI.14848	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	990	330	I	M	atC/atG	-0,57	0	0	benign	0	neutral	0,38	neutral	1,9	neutral	-0,93	neutral	-1,93	low_impact	1,91	neutral	0,93	neutral	0,78	deleterious	1,98	16,09	0,21	0,45	neutral	0,35	neutral	0,29	neutral	0,32	neutral	0,46	1	neutral	0,62	deleterious	0,69	neutral	-6	neutral	0,13	medium_impact	1,95	medium_impact	0,09	medium_impact	0,46	0,35	0,8	NA	NA	N	0,41	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5460	5460	G	C	MI.14849	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	991	331	A	P	Gcc/Ccc	-8,9	0	0,21	benign	0	neutral	0,23	neutral	1,99	neutral	-0,08	neutral	-1,78	neutral_impact	0,34	neutral	0,82	neutral	0,57	deleterious	1,96	15,94	0,11	0,4	disease	0,87	disease	0,58	disease	0,56	disease	0,67	3	neutral	0,77	deleterious	0,62	neutral	-6	neutral	0,28	medium_impact	1,95	medium_impact	-0,08	medium_impact	-0,86	0,4	0,8	NA	NA	N	0,3	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8384	8384	A	T	MI.1485	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	19	7	T	S	Acc/Tcc	-2,42	0	0	benign	0,01	neutral	0,84	neutral	2,18	neutral	2,3	neutral	1,84	neutral_impact	-1,11	neutral	0,93	neutral	0,94	neutral	-0,88	0,03	0,37202141	0,85	neutral	0,1	neutral	0,01	neutral	0,34	neutral	0,08	8	neutral	0,13	deleterious	0,92	neutral	-6	neutral	0,09	medium_impact	1,14	medium_impact	0,7	low_impact	-2,05	0,64	0,85	5,88	6,93	N	0,33	N	0,05	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5460	5460	G	A	MI.14850	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	991	331	A	T	Gcc/Acc	-8,9	0	0,21	benign	0	neutral	0,63	neutral	2,12	neutral	1,12	neutral	0,8	neutral_impact	-1,01	neutral	0,95	neutral	0,98	deleterious	0,76	9,23	0,18	0,45	neutral	0,37	neutral	0,06	neutral	0,31	neutral	0,21	6	neutral	0,37	deleterious	0,82	neutral	-6	neutral	0,1	medium_impact	1,95	medium_impact	0,34	low_impact	-2	0,65	0,8	NA	NA	N	0,33	N	0,02	polymorphism	1	0,01	rs3021088	.	.	.	.	.	.	.	.	G5460A	AD/PD	+	+	P.M.	8
chrM	5460	5460	G	T	MI.14851	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	991	331	A	S	Gcc/Tcc	-8,9	0	0,21	benign	0	neutral	0,55	neutral	2	neutral	0,02	neutral	-0,79	neutral_impact	0	damaging	0,37	neutral	0,96	deleterious	0,65	8,48	0,23	0,45	neutral	0,42	neutral	0,13	neutral	0,35	neutral	0,32	4	neutral	0,45	deleterious	0,78	neutral	-6	neutral	0,13	medium_impact	1,95	medium_impact	0,26	low_impact	-1,14	0,28	0,8	NA	NA	P	0,8	P	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	G5460T	AD	+	+	Reported	5
chrM	5461	5461	C	A	MI.14852	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	992	331	A	D	gCc/gAc	-1,26	0	0	benign	0	neutral	0,18	neutral	1,89	deleterious	-4,17	neutral	-2,03	low_impact	1,32	neutral	0,88	neutral	0,5	deleterious	2,69	20,7	0,09	0,35	disease	0,91	disease	0,55	disease	0,72	disease	0,8	6	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,25	medium_impact	1,95	medium_impact	-0,16	medium_impact	-0,03	0,24	0,8	NA	NA	N	0,36	N	0,38	polymorphism	1	0,03	rs878985080	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5461	5461	C	T	MI.14853	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	992	331	A	V	gCc/gTc	-1,26	0	0	benign	0	neutral	0,66	neutral	2,06	neutral	0,63	neutral	2,7	neutral_impact	-1,07	neutral	0,93	neutral	0,97	deleterious	0,82	9,6	0,16	0,45	neutral	0,33	neutral	0,14	neutral	0,36	neutral	0,28	4	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,37	low_impact	-2,05	0,69	0,85	NA	NA	N	0,27	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5461	5461	C	G	MI.14854	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	992	331	A	G	gCc/gGc	-1,26	0	0	benign	0	neutral	0,37	neutral	1,9	deleterious	-3,03	deleterious	-2,64	low_impact	1,32	neutral	0,91	neutral	0,58	deleterious	2,16	17,26	0,2	0,45	disease	0,66	neutral	0,25	disease	0,59	disease	0,58	2	neutral	0,63	deleterious	0,69	neutral	-6	neutral	0,17	medium_impact	1,95	medium_impact	0,08	medium_impact	-0,03	0,5	0,8	NA	NA	N	0,38	N	0,35	polymorphism	1	0,06	rs878985080	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5463	5463	C	A	MI.14855	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	994	332	L	I	Ctt/Att	-14,45	0	0	benign	0,01	neutral	0,4	neutral	1,87	neutral	-0,6	neutral	-0,56	low_impact	0,96	neutral	0,92	neutral	0,91	neutral	1,61	13,88	0,24	0,45	neutral	0,41	neutral	0,08	neutral	0,36	neutral	0,28	4	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,16	medium_impact	1,03	medium_impact	0,11	medium_impact	-0,34	0,49	0,8	NA	NA	N	0,49	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5463	5463	C	T	MI.14856	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	994	332	L	F	Ctt/Ttt	-14,45	0	0	benign	0,07	neutral	0,71	neutral	1,68	neutral	-2,23	neutral	-2,38	low_impact	1,77	neutral	0,96	neutral	0,8	deleterious	3,95	23,6	0,23	0,45	disease	0,64	neutral	0,31	neutral	0,48	disease	0,61	2	neutral	0,2	deleterious	0,82	neutral	-6	neutral	0,31	medium_impact	0,23	medium_impact	0,42	medium_impact	0,35	0,51	0,8	NA	NA	N	0,27	N	0,36	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5463	5463	C	G	MI.14857	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	994	332	L	V	Ctt/Gtt	-14,45	0	0	benign	0,01	neutral	0,5	neutral	1,67	neutral	-2,35	neutral	-1,2	medium_impact	2,12	neutral	0,87	neutral	0,94	deleterious	2,17	17,3	0,24	0,45	neutral	0,4	neutral	0,21	neutral	0,46	neutral	0,41	2	neutral	0,49	deleterious	0,75	neutral	-3	neutral	0,16	medium_impact	1,03	medium_impact	0,21	medium_impact	0,64	0,33	0,8	NA	NA	N	0,43	N	0,29	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5464	5464	T	G	MI.14858	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	995	332	L	R	cTt/cGt	-8,2	0	0	benign	0,03	neutral	0,35	neutral	1,59	deleterious	-5,06	deleterious	-4,37	medium_impact	2,92	neutral	0,82	neutral	0,43	deleterious	4,24	23,9	0,09	0,35	disease	0,89	disease	0,68	disease	0,76	disease	0,78	6	neutral	0,63	deleterious	0,66	neutral	-3	neutral	0,42	medium_impact	0,59	medium_impact	0,06	medium_impact	1,31	0,25	0,8	NA	NA	N	0,35	N	0,74	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5464	5464	T	A	MI.14859	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	995	332	L	H	cTt/cAt	-8,2	0	0	benign	0,19	neutral	0,54	neutral	1,59	deleterious	-5,59	deleterious	-4,93	medium_impact	2,92	neutral	0,81	neutral	0,49	deleterious	4,16	23,8	0,11	0,4	disease	0,92	disease	0,54	disease	0,73	disease	0,79	6	neutral	0,35	deleterious	0,68	neutral	-3	deleterious	0,56	medium_impact	-0,22	medium_impact	0,25	medium_impact	1,31	0,24	0,8	NA	NA	N	0,28	N	0,75	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8385	8385	C	G	MI.1486	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	20	7	T	S	aCc/aGc	-0,8	0	0	benign	0,01	neutral	0,84	neutral	2,18	neutral	2,3	neutral	1,84	neutral_impact	-1,11	neutral	0,93	neutral	0,94	neutral	-1,19	0,01	0,37202141	0,85	neutral	0,1	neutral	0,01	neutral	0,34	neutral	0,08	8	neutral	0,13	deleterious	0,92	neutral	-6	neutral	0,09	medium_impact	1,14	medium_impact	0,7	low_impact	-2,05	0,64	0,85	5,88	6,93	N	0,34	N	0,05	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5464	5464	T	C	MI.14860	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	995	332	L	P	cTt/cCt	-8,2	0	0	benign	0,04	neutral	0,2	neutral	1,62	deleterious	-3,52	deleterious	-4,95	medium_impact	2,58	neutral	0,79	neutral	0,48	deleterious	3,91	23,5	0,1	0,4	disease	0,92	disease	0,67	disease	0,76	disease	0,8	6	neutral	0,79	deleterious	0,58	neutral	-3	neutral	0,43	medium_impact	0,47	medium_impact	-0,13	medium_impact	1,03	0,23	0,8	NA	NA	N	0,33	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5466	5466	A	C	MI.14861	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	997	333	T	P	Acc/Ccc	-5,66	0	0,01	benign	0,06	neutral	0,28	neutral	1,87	neutral	-2,06	neutral	-2,43	low_impact	1,76	neutral	0,84	neutral	0,44	deleterious	3,46	23	0,09	0,35	disease	0,76	disease	0,8	disease	0,77	disease	0,81	6	neutral	0,69	deleterious	0,61	neutral	-6	deleterious	0,48	medium_impact	0,3	medium_impact	-0,02	medium_impact	0,34	0,4	0,8	NA	NA	N	0,31	N	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5466	5466	A	T	MI.14862	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	997	333	T	S	Acc/Tcc	-5,66	0	0,01	benign	0	neutral	0,61	neutral	2,6	neutral	2,51	neutral	1,89	neutral_impact	-2,05	neutral	0,78	neutral	0,9	deleterious	0,41	6,74	0,32	0,5	neutral	0,36	neutral	0,03	neutral	0,35	neutral	0,17	7	neutral	0,39	deleterious	0,81	neutral	-6	neutral	0,11	medium_impact	1,95	medium_impact	0,32	low_impact	-2,87	0,46	0,8	NA	NA	N	0,34	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5466	5466	A	G	MI.14863	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	997	333	T	A	Acc/Gcc	-5,66	0	0,01	benign	0,01	neutral	0,72	neutral	2,1	neutral	0,72	neutral	-0,65	neutral_impact	0,03	neutral	0,98	neutral	0,85	deleterious	2,17	17,33	0,22	0,45	neutral	0,42	neutral	0,19	neutral	0,42	neutral	0,35	3	neutral	0,26	deleterious	0,86	neutral	-6	neutral	0,15	medium_impact	1,03	medium_impact	0,44	low_impact	-1,12	0,17	0,8	NA	NA	N	0,3	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5467	5467	C	A	MI.14864	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	998	333	T	N	aCc/aAc	-0,11	0	0	benign	0,02	neutral	0,34	neutral	1,89	neutral	-1,68	neutral	-0,68	low_impact	1,76	neutral	0,84	neutral	0,56	deleterious	3,56	23,1	0,3	0,45	disease	0,59	disease	0,67	disease	0,66	disease	0,73	5	neutral	0,65	deleterious	0,66	neutral	-6	neutral	0,29	medium_impact	0,75	medium_impact	0,05	medium_impact	0,34	0,44	0,8	NA	NA	N	0,29	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5467	5467	C	T	MI.14865	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	998	333	T	I	aCc/aTc	-0,11	0	0	benign	0,06	neutral	0,7	neutral	1,87	neutral	-2,44	deleterious	-3,24	low_impact	0,87	neutral	0,86	neutral	0,52	deleterious	3,96	23,6	0,14	0,4	disease	0,57	disease	0,58	disease	0,63	disease	0,71	4	neutral	0,22	deleterious	0,82	neutral	-6	neutral	0,39	medium_impact	0,3	medium_impact	0,41	medium_impact	-0,41	0,22	0,8	NA	NA	N	0,2	N	0,76	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5467	5467	C	G	MI.14866	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	998	333	T	S	aCc/aGc	-0,11	0	0	benign	0	neutral	0,61	neutral	2,6	neutral	2,51	neutral	1,89	neutral_impact	-2,05	neutral	0,78	neutral	0,9	deleterious	0,63	8,33	0,32	0,5	neutral	0,36	neutral	0,03	neutral	0,35	neutral	0,17	7	neutral	0,39	deleterious	0,81	neutral	-6	neutral	0,11	medium_impact	1,95	medium_impact	0,32	low_impact	-2,87	0,46	0,8	NA	NA	N	0,34	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5469	5469	A	G	MI.14867	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1000	334	T	A	Acg/Gcg	-12,83	0	0	benign	0,05	neutral	0,55	neutral	1,78	neutral	-2,11	deleterious	-4,05	medium_impact	2,12	neutral	0,86	neutral	0,72	deleterious	3,18	22,7	0,29	0,45	neutral	0,43	neutral	0,24	neutral	0,42	neutral	0,45	1	neutral	0,4	deleterious	0,75	neutral	-3	neutral	0,28	medium_impact	0,37	medium_impact	0,26	medium_impact	0,64	0,19	0,8	4,9	8,12	N	0,35	N	0,57	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5469	5469	A	C	MI.14868	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1000	334	T	P	Acg/Ccg	-12,83	0	0	benign	0,28	neutral	0,25	neutral	1,73	deleterious	-4,42	deleterious	-5,09	medium_impact	2,43	neutral	0,78	damaging	0,1	deleterious	3,47	23	0,11	0,4	disease	0,9	disease	0,77	disease	0,71	disease	0,8	6	neutral	0,7	deleterious	0,49	neutral	-3	deleterious	0,66	medium_impact	-0,42	medium_impact	-0,06	medium_impact	0,9	0,39	0,8	4,9	8,12	N	0,23	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5469	5469	A	T	MI.14869	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1000	334	T	S	Acg/Tcg	-12,83	0	0	benign	0,01	neutral	0,52	neutral	1,79	neutral	-1,97	deleterious	-3,14	low_impact	1,94	neutral	0,85	neutral	0,9	deleterious	1,81	15,04	0,37	0,5	neutral	0,38	neutral	0,31	neutral	0,41	neutral	0,46	1	neutral	0,47	deleterious	0,76	neutral	-6	neutral	0,15	medium_impact	1,03	medium_impact	0,23	medium_impact	0,49	0,48	0,8	4,9	8,12	N	0,37	N	0,52	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8385	8385	C	T	MI.1487	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	20	7	T	I	aCc/aTc	-0,8	0	0	benign	0,03	neutral	0,67	neutral	2,02	neutral	-2,75	deleterious	-3,23	medium_impact	1,98	neutral	0,99	neutral	0,56	deleterious	2,01	16,29	0,37006987	0,85	disease	0,59	neutral	0,17	disease	0,55	neutral	0,18	6	neutral	0,29	deleterious	0,82	neutral	-3	neutral	0,21	medium_impact	0,68	medium_impact	0,47	medium_impact	0,6	0,43	0,85	5,88	6,93	N	0,36	N	0,48	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5470	5470	C	T	MI.14870	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1001	334	T	M	aCg/aTg	0,13	0	0	possibly_damaging	0,65	neutral	0,29	neutral	1,79	neutral	-1,96	deleterious	-4,61	medium_impact	2,43	neutral	0,9	damaging	0,23	deleterious	4,05	23,7	0,15	0,45	disease	0,63	neutral	0,45	neutral	0,44	disease	0,62	2	neutral	0,75	neutral	0,32	NA	0	deleterious	0,62	low_impact	-1,04	medium_impact	-0,01	medium_impact	0,9	0,46	0,8	4,9	8,12	N	0,44	N	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5470	5470	C	A	MI.14871	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1001	334	T	K	aCg/aAg	0,13	0	0	benign	0,11	neutral	0,31	neutral	1,73	deleterious	-4,4	deleterious	-5	medium_impact	3,33	neutral	0,85	damaging	0,11	deleterious	4,39	24,1	0,13	0,4	disease	0,8	disease	0,72	disease	0,76	disease	0,81	6	neutral	0,65	deleterious	0,6	neutral	-3	deleterious	0,53	medium_impact	0,03	medium_impact	0,02	medium_impact	1,66	0,42	0,8	4,9	8,12	N	0,36	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5472	5472	C	A	MI.14872	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1003	335	L	M	Cta/Ata	-6,12	0	0	possibly_damaging	0,58	neutral	0,39	neutral	1,85	neutral	-0,84	neutral	0,17	neutral_impact	0,1	neutral	0,84	neutral	0,91	neutral	1,1	11,22	0,15	0,4	disease	0,69	neutral	0,03	neutral	0,27	neutral	0,3	4	neutral	0,63	neutral	0,41	neutral	-3	deleterious	0,57	medium_impact	-0,93	medium_impact	0,1	low_impact	-1,06	0,48	0,8	NA	NA	N	0,45	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5472	5472	C	G	MI.14873	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1003	335	L	V	Cta/Gta	-6,12	0	0	benign	0,1	neutral	0,11	neutral	1,73	neutral	-2	neutral	-1,89	medium_impact	2,46	neutral	0,88	neutral	0,7	deleterious	3,32	22,9	0,16	0,45	disease	0,72	neutral	0,26	disease	0,53	disease	0,59	2	neutral	0,88	deleterious	0,51	neutral	-3	neutral	0,42	medium_impact	0,08	medium_impact	-0,3	medium_impact	0,93	0,42	0,8	NA	NA	N	0,45	N	0,31	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5473	5473	T	A	MI.14874	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1004	335	L	Q	cTa/cAa	-5,66	0	0	possibly_damaging	0,67	neutral	0,11	neutral	1,64	deleterious	-5,01	deleterious	-3,91	medium_impact	3,16	neutral	0,86	neutral	0,52	deleterious	4,12	23,8	0,09	0,35	disease	0,95	neutral	0,5	disease	0,64	disease	0,82	6	neutral	0,9	neutral	0,22	NA	0	deleterious	0,72	low_impact	-1,08	medium_impact	-0,3	medium_impact	1,52	0,32	0,8	NA	NA	N	0,44	N	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5473	5473	T	G	MI.14875	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1004	335	L	R	cTa/cGa	-5,66	0	0	possibly_damaging	0,67	neutral	0,11	neutral	1,64	deleterious	-4,83	deleterious	-4,3	medium_impact	3,16	neutral	0,85	neutral	0,45	deleterious	4,22	23,9	0,07	0,35	disease	0,91	disease	0,75	disease	0,75	disease	0,83	7	neutral	0,9	neutral	0,22	NA	0	deleterious	0,78	low_impact	-1,08	medium_impact	-0,3	medium_impact	1,52	0,28	0,8	NA	NA	N	0,38	N	0,91	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5473	5473	T	C	MI.14876	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1004	335	L	P	cTa/cCa	-5,66	0	0	possibly_damaging	0,67	deleterious	0,04	neutral	1,64	deleterious	-5,41	deleterious	-5,22	medium_impact	2,82	neutral	0,79	neutral	0,36	deleterious	3,97	23,6	0,07	0,35	disease	0,96	disease	0,73	disease	0,76	disease	0,86	7	neutral	0,96	neutral	0,19	deleterious	4	deleterious	0,79	low_impact	-1,08	medium_impact	-0,56	medium_impact	1,23	0,33	0,8	NA	NA	N	0,29	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5475	5475	C	T	MI.14877	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1006	336	L	F	Ctc/Ttc	-5,89	0	0	probably_damaging	0,98	neutral	0,2	neutral	1,6	deleterious	-3,14	neutral	-1,86	medium_impact	2,92	neutral	0,94	neutral	0,74	deleterious	3,96	23,6	0,26	0,45	disease	0,63	neutral	0,36	disease	0,59	disease	0,62	2	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,72	low_impact	-2,34	medium_impact	-0,13	medium_impact	1,31	0,48	0,8	5,48	8,52	N	0,5	N	0,27	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5475	5475	C	A	MI.14878	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1006	336	L	I	Ctc/Atc	-5,89	0	0	probably_damaging	0,93	neutral	0,34	neutral	1,68	neutral	-1,88	neutral	-0,26	low_impact	1,56	neutral	0,92	neutral	0,9	deleterious	2,65	20,5	0,26	0,45	neutral	0,45	neutral	0,24	neutral	0,4	neutral	0,43	1	neutral	0,94	neutral	0,21	neutral	-2	deleterious	0,65	low_impact	-1,83	medium_impact	0,05	medium_impact	0,17	0,39	0,8	5,48	8,52	N	0,48	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5475	5475	C	G	MI.14879	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1006	336	L	V	Ctc/Gtc	-5,89	0	0	possibly_damaging	0,89	neutral	0,11	neutral	1,63	neutral	-2,6	neutral	-0,41	medium_impact	2,71	neutral	0,92	neutral	0,7	deleterious	3,26	22,8	0,22	0,45	neutral	0,46	neutral	0,33	disease	0,58	neutral	0,48	1	neutral	0,96	neutral	0,11	NA	0	deleterious	0,66	low_impact	-1,63	medium_impact	-0,3	medium_impact	1,14	0,34	0,8	5,48	8,52	N	0,54	P	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8385	8385	C	A	MI.1488	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	20	7	T	N	aCc/aAc	-0,8	0	0	benign	0,05	neutral	0,52	neutral	1,98	neutral	-2,16	neutral	-0,84	neutral_impact	0,7	neutral	0,99	neutral	0,68	neutral	1,67	14,23	0,42207444	0,85	neutral	0,5	neutral	0,17	disease	0,51	neutral	0,19	6	neutral	0,43	deleterious	0,74	neutral	-6	neutral	0,2	medium_impact	0,46	medium_impact	0,31	medium_impact	-0,5	0,7	0,85	5,88	6,93	N	0,43	N	0,14	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5476	5476	T	C	MI.14880	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1007	336	L	P	cTc/cCc	-1,03	0	0	probably_damaging	0,99	neutral	0,13	neutral	1,55	deleterious	-5,76	deleterious	-3,05	high_impact	3,61	neutral	0,85	neutral	0,41	deleterious	4,02	23,6	0,11	0,4	disease	0,84	disease	0,67	disease	0,77	disease	0,8	6	deleterious	0,99	neutral	0,07	deleterious	2	deleterious	0,81	low_impact	-2,62	medium_impact	-0,25	medium_impact	1,89	0,3	0,8	5,48	8,52	N	0,45	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5476	5476	T	G	MI.14881	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1007	336	L	R	cTc/cGc	-1,03	0	0	probably_damaging	0,98	deleterious	0,04	neutral	1,56	deleterious	-5,16	deleterious	-2,73	high_impact	3,61	neutral	0,87	neutral	0,44	deleterious	4,25	23,9	0,1	0,4	disease	0,77	disease	0,77	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,81	low_impact	-2,34	medium_impact	-0,56	medium_impact	1,89	0,28	0,8	5,48	8,52	N	0,47	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5476	5476	T	A	MI.14882	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1007	336	L	H	cTc/cAc	-1,03	0	0	probably_damaging	0,99	neutral	0,06	neutral	1,55	deleterious	-5,71	deleterious	-3,32	high_impact	3,61	neutral	0,89	neutral	0,45	deleterious	4,39	24,1	0,13	0,4	disease	0,83	disease	0,63	disease	0,74	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,77	low_impact	-2,62	medium_impact	-0,46	medium_impact	1,89	0,28	0,8	5,48	8,52	N	0,5	N	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5478	5478	C	A	MI.14883	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1009	337	L	M	Cta/Ata	-10,28	0	0	probably_damaging	0,98	neutral	0,23	neutral	1,27	deleterious	-3,38	neutral	-1,8	medium_impact	3,21	neutral	0,93	neutral	0,61	deleterious	3,78	23,4	0,16	0,45	disease	0,8	neutral	0,33	neutral	0,49	disease	0,59	2	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,73	low_impact	-2,34	medium_impact	-0,08	medium_impact	1,56	0,45	0,8	NA	NA	N	0,5	N	0,88	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5478	5478	C	G	MI.14884	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1009	337	L	V	Cta/Gta	-10,28	0	0	possibly_damaging	0,89	neutral	0,5	neutral	1,26	deleterious	-3,48	deleterious	-2,54	high_impact	4,01	neutral	0,87	damaging	0,16	deleterious	3,32	22,9	0,19	0,45	disease	0,81	neutral	0,42	disease	0,71	disease	0,67	3	neutral	0,88	neutral	0,31	deleterious	1	deleterious	0,73	low_impact	-1,63	medium_impact	0,21	high_impact	2,23	0,47	0,8	NA	NA	N	0,37	N	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5479	5479	T	C	MI.14885	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1010	337	L	P	cTa/cCa	0,13	0,01	0	probably_damaging	0,99	neutral	0,26	neutral	1,19	deleterious	-5,41	deleterious	-6,47	high_impact	3,66	neutral	0,94	damaging	0,15	deleterious	3,95	23,6	0,07	0,35	disease	0,96	disease	0,67	disease	0,7	disease	0,83	7	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-2,62	medium_impact	-0,04	medium_impact	1,94	0,18	0,8	NA	NA	N	0,42	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5479	5479	T	A	MI.14886	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1010	337	L	Q	cTa/cAa	0,13	0,01	0	probably_damaging	0,99	neutral	0,29	neutral	1,18	deleterious	-6,6	deleterious	-5,6	high_impact	4,01	neutral	0,89	damaging	0,14	deleterious	4,11	23,8	0,1	0,4	disease	0,95	disease	0,64	disease	0,72	disease	0,84	7	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,8	low_impact	-2,62	medium_impact	-0,01	high_impact	2,23	0,23	0,8	NA	NA	N	0,44	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5479	5479	T	G	MI.14887	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1010	337	L	R	cTa/cGa	0,13	0,01	0	probably_damaging	0,98	neutral	0,35	neutral	1,18	deleterious	-6,43	deleterious	-5,6	high_impact	4,01	neutral	0,88	damaging	0,12	deleterious	4,24	23,9	0,06	0,35	disease	0,94	disease	0,8	disease	0,8	disease	0,89	8	deleterious	0,98	neutral	0,19	deleterious	2	deleterious	0,86	low_impact	-2,34	medium_impact	0,06	high_impact	2,23	0,26	0,8	NA	NA	N	0,45	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5481	5481	C	A	MI.14888	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1012	338	P	T	Cct/Act	-15,37	0	0	probably_damaging	0,99	neutral	0,38	neutral	1,2	deleterious	-4,08	deleterious	-7,59	high_impact	3,98	neutral	0,83	damaging	0,11	deleterious	3,76	23,3	0,18	0,45	disease	0,68	disease	0,57	disease	0,75	disease	0,76	5	deleterious	0,99	neutral	0,2	deleterious	2	deleterious	0,76	low_impact	-2,62	medium_impact	0,09	high_impact	2,21	0,62	0,8	NA	NA	N	0,34	N	0,88	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5481	5481	C	G	MI.14889	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1012	338	P	A	Cct/Gct	-15,37	0	0	probably_damaging	0,98	neutral	0,55	neutral	1,18	deleterious	-4,69	deleterious	-7,59	medium_impact	3,29	neutral	0,85	damaging	0,15	deleterious	3,08	22,5	0,21	0,45	disease	0,66	neutral	0,43	disease	0,75	disease	0,64	3	neutral	0,98	neutral	0,29	deleterious	1	deleterious	0,72	low_impact	-2,34	medium_impact	0,26	medium_impact	1,63	0,57	0,8	NA	NA	N	0,26	N	0,72	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8387	8387	G	T	MI.1489	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	22	8	V	L	Gta/Tta	-9,59	0	0	probably_damaging	0,96	neutral	0,67	neutral	1,99	neutral	-0,4	neutral	-1,28	low_impact	1,1	neutral	0,99	neutral	0,54	deleterious	3,37	22,9	0,66698427	0,85	neutral	0,26	neutral	0,15	neutral	0,47	neutral	0,16	7	neutral	0,95	neutral	0,36	neutral	-2	deleterious	0,63	low_impact	-2,07	medium_impact	0,47	medium_impact	-0,16	0,63	0,85	2,94	7,06	N	0,37	N	0,49	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5481	5481	C	T	MI.14890	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1012	338	P	S	Cct/Tct	-15,37	0	0	probably_damaging	0,99	neutral	0,45	neutral	1,2	deleterious	-4,06	deleterious	-7,59	medium_impact	3,44	neutral	0,86	damaging	0,14	deleterious	3,94	23,5	0,22	0,45	neutral	0,47	disease	0,62	disease	0,74	disease	0,73	5	deleterious	0,99	neutral	0,23	deleterious	1	deleterious	0,72	low_impact	-2,62	medium_impact	0,16	medium_impact	1,75	0,16	0,8	NA	NA	N	0,3	N	0,72	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5482	5482	C	A	MI.14891	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1013	338	P	H	cCt/cAt	4,29	0,98	0	probably_damaging	0,99	neutral	0,52	neutral	1,14	deleterious	-6,89	deleterious	-8,54	high_impact	3,63	neutral	0,85	damaging	0,09	deleterious	4,14	23,8	0,15	0,4	disease	0,9	disease	0,76	disease	0,82	disease	0,84	7	deleterious	0,99	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-2,62	medium_impact	0,23	medium_impact	1,91	0,35	0,8	NA	NA	P	0,59	P	0,71	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5482	5482	C	G	MI.14892	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1013	338	P	R	cCt/cGt	4,29	0,98	0	probably_damaging	0,99	neutral	0,33	neutral	1,14	deleterious	-6,34	deleterious	-8,54	high_impact	3,98	neutral	0,87	damaging	0,12	deleterious	3,6	23,2	0,13	0,4	disease	0,8	disease	0,83	disease	0,83	disease	0,85	7	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-2,62	medium_impact	0,04	high_impact	2,21	0,48	0,8	NA	NA	P	0,65	P	0,56	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5482	5482	C	T	MI.14893	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1013	338	P	L	cCt/cTt	4,29	0,98	0	probably_damaging	0,99	neutral	0,95	neutral	1,27	deleterious	-3,05	deleterious	-9,48	high_impact	3,63	neutral	0,92	damaging	0,11	deleterious	4,3	24	0,15	0,45	disease	0,62	disease	0,78	disease	0,72	disease	0,74	5	deleterious	0,99	deleterious	0,48	deleterious	2	deleterious	0,76	low_impact	-2,62	medium_impact	0,92	medium_impact	1,91	0,54	0,8	NA	NA	N	0,49	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5484	5484	A	T	MI.14894	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1015	339	I	F	Atc/Ttc	-10,98	0	0	benign	0,28	neutral	0,78	neutral	1,75	neutral	-2,1	neutral	-1,94	medium_impact	2,12	neutral	0,85	neutral	0,5	deleterious	3,66	23,2	0,14	0,4	disease	0,52	disease	0,51	disease	0,71	disease	0,73	5	neutral	0,18	deleterious	0,75	neutral	-3	deleterious	0,55	medium_impact	-0,42	medium_impact	0,51	medium_impact	0,64	0,57	0,8	NA	NA	N	0,22	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5484	5484	A	C	MI.14895	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1015	339	I	L	Atc/Ctc	-10,98	0	0	benign	0,02	neutral	1	neutral	2,22	neutral	0,86	neutral	1,21	neutral_impact	-1,22	neutral	0,9	neutral	0,9	neutral	-0,61	0,12	0,19	0,45	neutral	0,37	neutral	0,11	neutral	0,27	neutral	0,22	6	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,15	medium_impact	0,75	high_impact	1,87	low_impact	-2,17	0,47	0,8	NA	NA	N	0,33	N	0,1	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5484	5484	A	G	MI.14896	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1015	339	I	V	Atc/Gtc	-10,98	0	0	benign	0	neutral	0,63	neutral	1,77	neutral	-1,78	neutral	-0,7	low_impact	1,26	neutral	0,95	neutral	0,84	deleterious	0,23	5,02	0,2	0,45	neutral	0,46	neutral	0,17	neutral	0,43	neutral	0,31	4	neutral	0,37	deleterious	0,82	neutral	-6	neutral	0,14	medium_impact	1,95	medium_impact	0,34	medium_impact	-0,08	0,35	0,8	NA	NA	N	0,36	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5485	5485	T	G	MI.14897	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1016	339	I	S	aTc/aGc	-2,19	0	0	benign	0,28	neutral	0,56	neutral	1,74	neutral	-2,23	deleterious	-3,56	medium_impact	2,46	neutral	0,85	neutral	0,54	deleterious	4,04	23,7	0,09	0,35	disease	0,63	disease	0,56	disease	0,67	disease	0,72	4	neutral	0,34	deleterious	0,64	neutral	-3	deleterious	0,5	medium_impact	-0,42	medium_impact	0,27	medium_impact	0,93	0,34	0,8	NA	NA	N	0,23	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5485	5485	T	C	MI.14898	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1016	339	I	T	aTc/aCc	-2,19	0	0	benign	0,11	neutral	0,62	neutral	1,76	neutral	-2,01	deleterious	-2,74	medium_impact	2,12	neutral	0,85	neutral	0,59	deleterious	1,91	15,63	0,16	0,45	neutral	0,41	neutral	0,31	disease	0,61	neutral	0,5	0	neutral	0,28	deleterious	0,76	neutral	-3	neutral	0,38	medium_impact	0,03	medium_impact	0,33	medium_impact	0,64	0,31	0,8	NA	NA	N	0,27	N	0,83	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5485	5485	T	A	MI.14899	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1016	339	I	N	aTc/aAc	-2,19	0	0	possibly_damaging	0,56	neutral	0,27	neutral	1,68	deleterious	-5,02	deleterious	-4,51	medium_impact	2,46	neutral	0,86	neutral	0,47	deleterious	4,3	24	0,19	0,45	disease	0,83	disease	0,59	disease	0,69	disease	0,74	5	neutral	0,73	neutral	0,36	NA	0	deleterious	0,66	medium_impact	-0,89	medium_impact	-0,03	medium_impact	0,93	0,32	0,8	NA	NA	N	0,35	N	0,96	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8596	8596	A	T	MI.149	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	70	24	I	F	Att/Ttt	-7,51	0	0	probably_damaging	0,99	deleterious	0,03	neutral	4,07	neutral	-1,56	deleterious	-2,98	low_impact	1,17	neutral	0,87	neutral	0,6	deleterious	3,48	23,1	0,4	0,65	neutral	0,47	disease	0,52	neutral	0,41	neutral	0,5	0	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,72	low_impact	-2,65	medium_impact	-0,56	medium_impact	-0,1	0,58	0,9	18,14	17,22	N	0,43	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8387	8387	G	C	MI.1490	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	22	8	V	L	Gta/Cta	-9,59	0	0	probably_damaging	0,96	neutral	0,67	neutral	1,99	neutral	-0,4	neutral	-1,28	low_impact	1,1	neutral	0,99	neutral	0,54	deleterious	3,26	22,8	0,66698427	0,85	neutral	0,26	neutral	0,15	neutral	0,47	neutral	0,16	7	neutral	0,95	neutral	0,36	neutral	-2	deleterious	0,63	low_impact	-2,07	medium_impact	0,47	medium_impact	-0,16	0,63	0,85	2,94	7,06	N	0,37	N	0,49	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5486	5486	C	A	MI.14900	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1017	339	I	M	atC/atA	2,9	0,13	0	possibly_damaging	0,46	neutral	0,31	neutral	1,8	neutral	-1,38	neutral	0,36	low_impact	1,18	neutral	0,94	neutral	0,92	deleterious	2,36	18,54	0,23	0,45	neutral	0,47	neutral	0,2	neutral	0,36	neutral	0,36	3	neutral	0,65	neutral	0,43	neutral	-3	deleterious	0,54	medium_impact	-0,73	medium_impact	0,02	medium_impact	-0,15	0,55	0,8	NA	NA	N	0,51	P	0,62	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5486	5486	C	G	MI.14901	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1017	339	I	M	atC/atG	2,9	0,13	0	possibly_damaging	0,46	neutral	0,31	neutral	1,8	neutral	-1,38	neutral	0,36	low_impact	1,18	neutral	0,94	neutral	0,92	deleterious	1,96	15,96	0,23	0,45	neutral	0,47	neutral	0,2	neutral	0,36	neutral	0,36	3	neutral	0,65	neutral	0,43	neutral	-3	deleterious	0,54	medium_impact	-0,73	medium_impact	0,02	medium_impact	-0,15	0,55	0,8	NA	NA	N	0,51	P	0,62	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5487	5487	T	C	MI.14902	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1018	340	S	P	Tcc/Ccc	-12,83	0	0	benign	0,22	neutral	0,26	neutral	1,86	deleterious	-3,96	deleterious	-2,52	low_impact	1,65	neutral	0,75	neutral	0,39	deleterious	3,8	23,4	0,13	0,4	disease	0,73	disease	0,78	disease	0,67	disease	0,76	5	neutral	0,69	deleterious	0,52	neutral	-6	deleterious	0,52	medium_impact	-0,29	medium_impact	-0,04	medium_impact	0,24	0,25	0,8	NA	NA	N	0,29	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5487	5487	T	G	MI.14903	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1018	340	S	A	Tcc/Gcc	-12,83	0	0	benign	0,02	neutral	0,52	neutral	2,01	neutral	0,06	neutral	-0,76	low_impact	0,88	neutral	0,97	neutral	0,97	deleterious	0,77	9,29	0,19	0,45	neutral	0,49	neutral	0,2	neutral	0,48	neutral	0,33	3	neutral	0,45	deleterious	0,75	neutral	-6	neutral	0,18	medium_impact	0,75	medium_impact	0,23	medium_impact	-0,4	0,33	0,8	NA	NA	N	0,35	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5487	5487	T	A	MI.14904	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1018	340	S	T	Tcc/Acc	-12,83	0	0	benign	0	neutral	0,45	neutral	2,23	neutral	1,46	neutral	1,1	neutral_impact	-0,27	neutral	0,89	neutral	0,94	neutral	-0,44	0,31	0,19	0,45	neutral	0,36	neutral	0,04	neutral	0,34	neutral	0,17	7	neutral	0,55	deleterious	0,73	neutral	-6	neutral	0,13	medium_impact	1,95	medium_impact	0,16	low_impact	-1,37	0,46	0,8	NA	NA	N	0,45	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5488	5488	C	A	MI.14905	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1019	340	S	Y	tCc/tAc	-1,26	0	0	possibly_damaging	0,47	neutral	1	neutral	1,9	neutral	-1,79	deleterious	-3,25	medium_impact	2,9	neutral	0,89	neutral	0,55	deleterious	4,11	23,7	0,1	0,4	disease	0,61	disease	0,61	disease	0,7	disease	0,74	5	neutral	0,47	deleterious	0,77	NA	0	deleterious	0,59	medium_impact	-0,75	high_impact	1,87	medium_impact	1,3	0,23	0,8	NA	NA	N	0,25	N	0,93	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5488	5488	C	G	MI.14906	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1019	340	S	C	tCc/tGc	-1,26	0	0	possibly_damaging	0,57	neutral	0,18	neutral	1,86	deleterious	-3,74	neutral	-2,26	medium_impact	2,9	neutral	0,8	neutral	0,43	deleterious	3,68	23,3	0,11	0,4	disease	0,93	disease	0,57	disease	0,67	disease	0,8	6	neutral	0,81	neutral	0,31	NA	0	deleterious	0,62	medium_impact	-0,91	medium_impact	-0,16	medium_impact	1,3	0,28	0,8	NA	NA	N	0,32	N	0,55	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5488	5488	C	T	MI.14907	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1019	340	S	F	tCc/tTc	-1,26	0	0	possibly_damaging	0,47	neutral	0,71	neutral	1,89	neutral	-1,89	deleterious	-3,16	medium_impact	2,9	neutral	0,87	neutral	0,54	deleterious	4,25	23,9	0,1	0,4	disease	0,88	disease	0,65	disease	0,7	disease	0,75	5	neutral	0,37	deleterious	0,62	NA	0	deleterious	0,64	medium_impact	-0,75	medium_impact	0,42	medium_impact	1,3	0,2	0,8	NA	NA	N	0,24	N	0,93	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5490	5490	C	A	MI.14908	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1021	341	P	T	Cct/Act	-2,42	0	0	probably_damaging	0,99	neutral	0,4	neutral	0,48	deleterious	-5,3	deleterious	-7,28	medium_impact	3,33	neutral	0,85	damaging	0,11	deleterious	3,78	23,4	0,21	0,45	disease	0,63	neutral	0,44	disease	0,74	disease	0,62	2	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,74	low_impact	-2,62	medium_impact	0,11	medium_impact	1,66	0,57	0,8	NA	NA	N	0,31	N	0,66	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5490	5490	C	G	MI.14909	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1021	341	P	A	Cct/Gct	-2,42	0	0	probably_damaging	0,98	neutral	0,51	neutral	0,46	deleterious	-5,78	deleterious	-7,52	medium_impact	3,19	neutral	0,87	damaging	0,14	deleterious	3,09	22,5	0,16	0,45	disease	0,62	neutral	0,3	disease	0,78	disease	0,64	3	neutral	0,98	neutral	0,27	deleterious	1	deleterious	0,71	low_impact	-2,34	medium_impact	0,22	medium_impact	1,54	0,64	0,8	NA	NA	N	0,4	N	0,48	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8387	8387	G	A	MI.1491	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	22	8	V	M	Gta/Ata	-9,59	0	0	probably_damaging	1	neutral	0,34	neutral	1,96	neutral	-1,67	neutral	-1,12	neutral_impact	0,55	neutral	0,98	neutral	0,69	deleterious	2,35	18,52	0,58788784	0,85	neutral	0,42	neutral	0,14	neutral	0,44	neutral	0,16	7	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	0,13	medium_impact	-0,63	0,64	0,85	2,94	7,06	N	0,52	P	0,44	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5490	5490	C	T	MI.14910	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1021	341	P	S	Cct/Tct	-2,42	0	0	probably_damaging	0,99	neutral	0,4	neutral	0,6	deleterious	-3,75	deleterious	-7,52	medium_impact	3,19	neutral	0,93	damaging	0,18	deleterious	3,94	23,5	0,18	0,45	disease	0,55	neutral	0,45	disease	0,74	disease	0,62	2	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,72	low_impact	-2,62	medium_impact	0,11	medium_impact	1,54	0,37	0,8	NA	NA	N	0,41	N	0,45	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5491	5491	C	A	MI.14911	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1022	341	P	H	cCt/cAt	2,21	0,92	0	probably_damaging	0,99	neutral	0,53	neutral	0,41	deleterious	-9,54	deleterious	-8,45	high_impact	3,54	neutral	0,86	damaging	0,08	deleterious	4,08	23,7	0,14	0,4	disease	0,8	disease	0,62	disease	0,82	disease	0,78	6	deleterious	0,99	neutral	0,27	deleterious	2	deleterious	0,78	low_impact	-2,62	medium_impact	0,24	medium_impact	1,84	0,35	0,8	NA	NA	N	0,45	N	0,85	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5491	5491	C	T	MI.14912	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1022	341	P	L	cCt/cTt	2,21	0,92	0	probably_damaging	0,99	neutral	0,67	neutral	0,43	deleterious	-6,86	deleterious	-9,11	high_impact	3,54	neutral	0,92	damaging	0,1	deleterious	4,36	24,1	0,18	0,45	disease	0,78	disease	0,62	disease	0,76	disease	0,77	5	deleterious	0,99	neutral	0,34	deleterious	2	deleterious	0,76	low_impact	-2,62	medium_impact	0,38	medium_impact	1,84	0,59	0,8	NA	NA	N	0,46	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5491	5491	C	G	MI.14913	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1022	341	P	R	cCt/cGt	2,21	0,92	0	probably_damaging	0,99	neutral	0,34	neutral	0,41	deleterious	-8,55	deleterious	-8,45	high_impact	3,88	neutral	0,88	damaging	0,1	deleterious	3,69	23,3	0,14	0,4	disease	0,64	disease	0,7	disease	0,84	disease	0,79	6	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,78	low_impact	-2,62	medium_impact	0,05	high_impact	2,12	0,48	0,8	NA	NA	P	0,55	P	0,86	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5493	5493	T	G	MI.14914	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1024	342	F	V	Ttt/Gtt	-8,66	0	0	benign	0,01	neutral	0,37	neutral	2,08	neutral	1,47	neutral	0,82	neutral_impact	-0,98	neutral	0,88	neutral	0,73	deleterious	4,11	23,7	0,15	0,4	disease	0,68	neutral	0,22	disease	0,55	disease	0,51	0	neutral	0,62	deleterious	0,68	neutral	-6	neutral	0,18	medium_impact	1,03	medium_impact	0,08	low_impact	-1,97	0,39	0,8	NA	NA	N	0,39	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5493	5493	T	C	MI.14915	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1024	342	F	L	Ttt/Ctt	-8,66	0	0	benign	0	neutral	1	neutral	2,37	neutral	3,25	neutral	1,46	neutral_impact	-2,2	neutral	0,98	neutral	0,98	neutral	1,01	10,7	0,18	0,45	disease	0,57	neutral	0,07	neutral	0,34	neutral	0,28	4	neutral	0	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,95	high_impact	1,87	low_impact	-3	0,55	0,8	NA	NA	N	0,35	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5493	5493	T	A	MI.14916	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1024	342	F	I	Ttt/Att	-8,66	0	0	benign	0,01	neutral	0,47	neutral	2,06	neutral	1,14	neutral	1,04	neutral_impact	-1,58	neutral	0,91	neutral	0,97	deleterious	2,97	22,1	0,15	0,45	disease	0,74	neutral	0,12	neutral	0,4	neutral	0,4	2	neutral	0,52	deleterious	0,73	neutral	-6	neutral	0,18	medium_impact	1,03	medium_impact	0,18	low_impact	-2,47	0,46	0,8	NA	NA	N	0,39	N	0,16	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5494	5494	T	G	MI.14917	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1025	342	F	C	tTt/tGt	-0,57	0	0	benign	0,19	neutral	0,08	neutral	1,96	neutral	-2,13	neutral	-0,45	neutral_impact	0	neutral	0,86	neutral	0,5	deleterious	4,33	24	0,1	0,4	disease	0,9	neutral	0,28	disease	0,64	disease	0,61	2	neutral	0,91	neutral	0,45	neutral	-6	deleterious	0,51	medium_impact	-0,22	medium_impact	-0,38	low_impact	-1,14	0,28	0,8	NA	NA	N	0,39	N	0,49	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5494	5494	T	A	MI.14918	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1025	342	F	Y	tTt/tAt	-0,57	0	0	benign	0,02	neutral	0,47	neutral	1,98	neutral	-0,6	neutral	-0,53	neutral_impact	0	neutral	0,9	neutral	0,61	deleterious	2,92	21,9	0,11	0,4	disease	0,58	neutral	0,12	disease	0,52	neutral	0,35	3	neutral	0,5	deleterious	0,73	neutral	-6	neutral	0,23	medium_impact	0,75	medium_impact	0,18	low_impact	-1,14	0,37	0,8	NA	NA	N	0,44	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5494	5494	T	C	MI.14919	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1025	342	F	S	tTt/tCt	-0,57	0	0	benign	0,02	neutral	0,36	neutral	2,07	neutral	1,26	neutral	-0,52	neutral_impact	-0,9	neutral	0,83	neutral	0,68	deleterious	4,21	23,9	0,07	0,35	neutral	0,49	neutral	0,16	disease	0,53	neutral	0,27	5	neutral	0,62	deleterious	0,67	neutral	-6	neutral	0,27	medium_impact	0,75	medium_impact	0,07	low_impact	-1,9	0,25	0,8	NA	NA	N	0,34	N	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8388	8388	T	G	MI.1492	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	23	8	V	G	gTa/gGa	1,52	0,18	0	probably_damaging	0,99	neutral	0,33	neutral	1,96	neutral	-1,44	deleterious	-2,56	low_impact	1,1	neutral	0,99	neutral	0,46	deleterious	3,58	23,2	0,33137158	0,85	disease	0,53	neutral	0,28	disease	0,52	neutral	0,17	7	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,72	low_impact	-2,65	medium_impact	0,12	medium_impact	-0,16	0,38	0,85	2,94	7,06	N	0,48	N	0,44	polymorphism	0,99	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5495	5495	T	G	MI.14920	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1026	342	F	L	ttT/ttG	-0,34	0	0,01	benign	0	neutral	1	neutral	2,37	neutral	3,25	neutral	1,46	neutral_impact	-2,2	neutral	0,98	neutral	0,98	neutral	1,27	12,12	0,18	0,45	disease	0,57	neutral	0,07	neutral	0,34	neutral	0,28	4	neutral	0	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,95	high_impact	1,87	low_impact	-3	0,55	0,8	NA	NA	N	0,35	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5495	5495	T	A	MI.14921	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1026	342	F	L	ttT/ttA	-0,34	0	0,01	benign	0	neutral	1	neutral	2,37	neutral	3,25	neutral	1,46	neutral_impact	-2,2	neutral	0,98	neutral	0,98	neutral	1,4	12,79	0,18	0,45	disease	0,57	neutral	0,07	neutral	0,34	neutral	0,28	4	neutral	0	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,95	high_impact	1,87	low_impact	-3	0,55	0,8	NA	NA	N	0,35	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5496	5496	A	C	MI.14922	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1027	343	M	L	Ata/Cta	-0,57	0	0	benign	0,32	neutral	1	neutral	2,31	neutral	2,12	neutral	-0,79	neutral_impact	-1,24	neutral	0,89	neutral	0,99	neutral	-0,98	0,02	0,16	0,45	neutral	0,29	neutral	0,1	neutral	0,42	neutral	0,24	5	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,21	medium_impact	-0,5	high_impact	1,87	low_impact	-2,19	0,25	0,8	6,63	8	N	0,39	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5496	5496	A	G	MI.14923	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1027	343	M	V	Ata/Gta	-0,57	0	0	possibly_damaging	0,52	neutral	0,41	neutral	2	neutral	-0,01	neutral	-1,97	neutral_impact	0,74	neutral	0,96	neutral	0,96	deleterious	0,03	2,87	0,16	0,45	neutral	0,27	neutral	0,19	disease	0,52	neutral	0,38	2	neutral	0,58	neutral	0,45	neutral	-3	neutral	0,27	medium_impact	-0,83	medium_impact	0,12	medium_impact	-0,52	0,2	0,8	6,63	8	N	0,4	N	0,08	polymorphism	1	0,03	rs879099820	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5496	5496	A	T	MI.14924	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1027	343	M	L	Ata/Tta	-0,57	0	0	benign	0,32	neutral	1	neutral	2,31	neutral	2,12	neutral	-0,79	neutral_impact	-1,24	neutral	0,89	neutral	0,99	neutral	-0,92	0,02	0,16	0,45	neutral	0,29	neutral	0,1	neutral	0,42	neutral	0,24	5	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,21	medium_impact	-0,5	high_impact	1,87	low_impact	-2,19	0,25	0,8	6,63	8	N	0,38	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5497	5497	T	A	MI.14925	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1028	343	M	K	aTa/aAa	-0,11	0	0	possibly_damaging	0,74	neutral	0,21	neutral	1,91	neutral	-2,85	deleterious	-3,96	low_impact	1,59	neutral	0,85	neutral	0,43	deleterious	2,37	18,64	0,1	0,4	disease	0,54	neutral	0,45	disease	0,73	disease	0,66	3	neutral	0,85	neutral	0,24	neutral	-3	deleterious	0,55	low_impact	-1,21	medium_impact	-0,11	medium_impact	0,19	0,24	0,8	6,63	8	N	0,34	N	0,48	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5497	5497	T	C	MI.14926	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1028	343	M	T	aTa/aCa	-0,11	0	0	possibly_damaging	0,74	neutral	0,44	neutral	1,98	neutral	-0,34	deleterious	-3,05	neutral_impact	0,74	neutral	0,95	neutral	0,75	deleterious	0,21	4,83	0,12	0,4	neutral	0,49	neutral	0,19	disease	0,66	neutral	0,4	2	neutral	0,73	neutral	0,35	neutral	-3	deleterious	0,5	low_impact	-1,21	medium_impact	0,15	medium_impact	-0,52	0,15	0,8	6,63	8	N	0,37	N	0,08	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5498	5498	A	C	MI.14927	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1029	343	M	I	atA/atC	2,9	0,03	0,01	possibly_damaging	0,64	neutral	0,66	neutral	2,38	neutral	2,42	neutral	-1,51	neutral_impact	-0,28	neutral	0,87	neutral	0,95	neutral	-0,12	1,6	0,12	0,4	neutral	0,24	neutral	0,05	neutral	0,41	neutral	0,18	6	neutral	0,57	deleterious	0,51	neutral	-3	neutral	0,33	low_impact	-1,03	medium_impact	0,37	low_impact	-1,38	0,24	0,8	6,63	8	N	0,45	N	0,05	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5498	5498	A	T	MI.14928	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1029	343	M	I	atA/atT	2,9	0,03	0,01	possibly_damaging	0,64	neutral	0,66	neutral	2,38	neutral	2,42	neutral	-1,51	neutral_impact	-0,28	neutral	0,87	neutral	0,95	neutral	-0,07	1,95	0,12	0,4	neutral	0,24	neutral	0,05	neutral	0,41	neutral	0,18	6	neutral	0,57	deleterious	0,51	neutral	-3	neutral	0,33	low_impact	-1,03	medium_impact	0,37	low_impact	-1,38	0,24	0,8	6,63	8	N	0,45	N	0,05	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5499	5499	C	A	MI.14929	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1030	344	L	M	Cta/Ata	-3,34	0	0	probably_damaging	0,98	neutral	0,32	neutral	1,74	neutral	-2,03	neutral	-0,59	neutral_impact	0,56	neutral	0,92	neutral	0,85	deleterious	2,15	17,21	0,15	0,45	neutral	0,47	neutral	0,06	neutral	0,39	neutral	0,25	5	deleterious	0,98	neutral	0,17	neutral	-2	deleterious	0,66	low_impact	-2,34	medium_impact	0,03	medium_impact	-0,67	0,49	0,8	6,92	10,05	N	0,53	P	0,39	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8388	8388	T	C	MI.1493	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	23	8	V	A	gTa/gCa	1,52	0,18	0	probably_damaging	0,97	neutral	0,51	neutral	2	neutral	-0,12	neutral	-0,52	neutral_impact	0,76	neutral	0,99	neutral	0,76	deleterious	3,26	22,8	0,66000491	0,85	neutral	0,29	neutral	0,11	neutral	0,5	neutral	0,14	7	neutral	0,97	neutral	0,27	neutral	-2	deleterious	0,66	low_impact	-2,19	medium_impact	0,3	medium_impact	-0,45	0,39	0,85	2,94	7,06	N	0,46	N	0,36	polymorphism	1	0,05	rs879199176	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5499	5499	C	G	MI.14930	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1030	344	L	V	Cta/Gta	-3,34	0	0	possibly_damaging	0,89	neutral	0,57	neutral	1,76	neutral	-1,84	neutral	-1,13	neutral_impact	0,74	neutral	0,92	neutral	0,75	deleterious	2,14	17,12	0,22	0,45	neutral	0,42	neutral	0,14	neutral	0,45	neutral	0,29	4	neutral	0,87	neutral	0,34	neutral	-3	deleterious	0,63	low_impact	-1,63	medium_impact	0,28	medium_impact	-0,52	0,34	0,8	6,92	10,05	N	0,36	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5500	5500	T	C	MI.14931	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1031	344	L	P	cTa/cCa	-5,89	0	0	probably_damaging	0,99	neutral	0,23	neutral	1,68	deleterious	-3,77	deleterious	-3	low_impact	1,5	neutral	0,79	damaging	0,12	deleterious	4,09	23,7	0,08	0,35	disease	0,82	neutral	0,41	disease	0,75	disease	0,72	4	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,78	low_impact	-2,62	medium_impact	-0,08	medium_impact	0,12	0,25	0,8	6,92	10,05	N	0,27	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5500	5500	T	A	MI.14932	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1031	344	L	Q	cTa/cAa	-5,89	0	0	probably_damaging	0,99	neutral	0,3	neutral	1,67	deleterious	-4,32	neutral	-2,29	low_impact	1,08	neutral	0,86	damaging	0,17	deleterious	4,31	24	0,11	0,4	disease	0,74	neutral	0,3	disease	0,65	disease	0,65	3	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,72	low_impact	-2,62	medium_impact	0	medium_impact	-0,24	0,24	0,8	6,92	10,05	N	0,31	N	0,56	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5500	5500	T	G	MI.14933	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1031	344	L	R	cTa/cGa	-5,89	0	0	probably_damaging	0,98	neutral	0,34	neutral	1,66	deleterious	-4,72	deleterious	-2,67	medium_impact	2,06	neutral	0,79	damaging	0,1	deleterious	4,27	24	0,07	0,35	disease	0,74	disease	0,53	disease	0,75	disease	0,76	5	deleterious	0,98	neutral	0,18	deleterious	1	deleterious	0,79	low_impact	-2,34	medium_impact	0,05	medium_impact	0,59	0,2	0,8	6,92	10,05	N	0,24	N	0,58	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5502	5502	A	C	MI.14934	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1033	345	M	L	Ata/Cta	-6,58	0	0	benign	0,18	neutral	1	neutral	2,09	neutral	0,89	neutral	-0,11	neutral_impact	0,62	neutral	0,94	neutral	0,99	deleterious	0,16	4,22	0,13	0,4	neutral	0,4	neutral	0,07	neutral	0,35	neutral	0,26	5	neutral	0,18	deleterious	0,91	neutral	-6	neutral	0,22	medium_impact	-0,19	high_impact	1,87	medium_impact	-0,62	0,23	0,8	11,24	8,11	N	0,35	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5502	5502	A	T	MI.14935	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1033	345	M	L	Ata/Tta	-6,58	0	0	benign	0,18	neutral	1	neutral	2,09	neutral	0,89	neutral	-0,11	neutral_impact	0,62	neutral	0,94	neutral	0,99	deleterious	0,26	5,3	0,13	0,4	neutral	0,4	neutral	0,07	neutral	0,35	neutral	0,26	5	neutral	0,18	deleterious	0,91	neutral	-6	neutral	0,22	medium_impact	-0,19	high_impact	1,87	medium_impact	-0,62	0,23	0,8	11,24	8,11	N	0,35	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5502	5502	A	G	MI.14936	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1033	345	M	V	Ata/Gta	-6,58	0	0	benign	0,26	neutral	0,55	neutral	1,98	neutral	-0,31	neutral	-0,23	low_impact	0,98	neutral	0,96	neutral	0,97	deleterious	-0,02	2,39	0,13	0,4	neutral	0,42	neutral	0,11	neutral	0,38	neutral	0,26	5	neutral	0,34	deleterious	0,65	neutral	-6	neutral	0,28	medium_impact	-0,38	medium_impact	0,26	medium_impact	-0,32	0,18	0,8	11,24	8,11	N	0,36	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5503	5503	T	A	MI.14937	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1034	345	M	K	aTa/aAa	-1,72	0	0	possibly_damaging	0,45	neutral	0,46	neutral	1,91	neutral	-2,33	neutral	-1,28	low_impact	0,98	neutral	0,9	neutral	0,44	deleterious	2,47	19,27	0,09	0,35	disease	0,56	neutral	0,28	disease	0,63	disease	0,53	1	neutral	0,5	deleterious	0,51	neutral	-3	deleterious	0,51	medium_impact	-0,72	medium_impact	0,17	medium_impact	-0,32	0,24	0,8	11,24	8,11	N	0,37	N	0,47	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5503	5503	T	C	MI.14938	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1034	345	M	T	aTa/aCa	-1,72	0	0	possibly_damaging	0,45	neutral	0,61	neutral	2,1	neutral	0,93	neutral	1,44	neutral_impact	0,17	neutral	0,94	neutral	0,97	neutral	-0,16	1,34	0,1	0,4	neutral	0,41	neutral	0,04	neutral	0,42	neutral	0,25	5	neutral	0,39	deleterious	0,58	neutral	-3	deleterious	0,45	medium_impact	-0,72	medium_impact	0,32	low_impact	-1	0,15	0,8	11,24	8,11	N	0,36	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5504	5504	A	C	MI.14939	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1035	345	M	I	atA/atC	-1,72	0	0	benign	0,34	neutral	0,7	neutral	2,02	neutral	0,28	neutral	-0,29	low_impact	0,98	neutral	0,95	neutral	0,98	neutral	-0,97	0,02	0,11	0,4	disease	0,53	neutral	0,09	neutral	0,36	neutral	0,25	5	neutral	0,25	deleterious	0,68	neutral	-6	neutral	0,37	medium_impact	-0,53	medium_impact	0,41	medium_impact	-0,32	0,24	0,8	11,24	8,11	N	0,37	N	0,06	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8388	8388	T	A	MI.1494	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	23	8	V	E	gTa/gAa	1,52	0,18	0	probably_damaging	0,99	neutral	0,26	neutral	1,99	neutral	-0,17	neutral	-1,58	low_impact	1,1	neutral	0,98	neutral	0,51	deleterious	4,38	24,1	0,30143898	0,85	disease	0,53	neutral	0,41	disease	0,58	neutral	0,22	6	deleterious	0,99	neutral	0,14	neutral	-2	deleterious	0,76	low_impact	-2,65	medium_impact	0,04	medium_impact	-0,16	0,51	0,85	2,94	7,06	N	0,48	N	0,45	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5504	5504	A	T	MI.14940	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1035	345	M	I	atA/atT	-1,72	0	0	benign	0,34	neutral	0,7	neutral	2,02	neutral	0,28	neutral	-0,29	low_impact	0,98	neutral	0,95	neutral	0,98	neutral	-0,91	0,02	0,11	0,4	disease	0,53	neutral	0,09	neutral	0,36	neutral	0,25	5	neutral	0,25	deleterious	0,68	neutral	-6	neutral	0,37	medium_impact	-0,53	medium_impact	0,41	medium_impact	-0,32	0,24	0,8	11,24	8,11	N	0,37	N	0,06	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5505	5505	A	G	MI.14941	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1036	346	I	V	Atc/Gtc	-9,36	0	0	benign	0	neutral	0,19	neutral	4,23	neutral	0,06	neutral	-0,42	neutral_impact	0	neutral	0,94	neutral	0,81	neutral	1,29	12,22	0,22	0,45	disease	0,56	neutral	0,04	neutral	0,35	neutral	0,22	6	neutral	0,81	deleterious	0,6	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	-0,14	low_impact	-1,14	0,36	0,8	NA	NA	N	0,5	N	0,7	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5505	5505	A	T	MI.14942	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1036	346	I	F	Atc/Ttc	-9,36	0	0	benign	0,01	neutral	0,31	neutral	4,08	neutral	-1,28	neutral	-1,71	neutral_impact	0	neutral	0,87	neutral	0,55	deleterious	2	16,2	0,11	0,4	disease	0,76	neutral	0,13	neutral	0,36	neutral	0,28	4	neutral	0,68	deleterious	0,65	neutral	-6	neutral	0,17	medium_impact	1,03	medium_impact	0,02	low_impact	-1,14	0,44	0,8	NA	NA	N	0,43	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5505	5505	A	C	MI.14943	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1036	346	I	L	Atc/Ctc	-9,36	0	0	benign	0	neutral	1	neutral	4,31	neutral	0,36	neutral	0,71	neutral_impact	0	neutral	0,9	neutral	0,93	neutral	-0,64	0,1	0,17	0,45	disease	0,54	neutral	0,02	neutral	0,21	neutral	0,2	6	neutral	0	deleterious	1	neutral	-6	neutral	0,11	medium_impact	1,95	high_impact	1,87	low_impact	-1,14	0,44	0,8	NA	NA	N	0,4	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5506	5506	T	C	MI.14944	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1037	346	I	T	aTc/aCc	-2,42	0	0	benign	0	neutral	0,23	neutral	4,08	neutral	-1,01	neutral	-0,87	neutral_impact	0	neutral	0,87	neutral	0,56	neutral	1,71	14,49	0,14	0,4	disease	0,64	neutral	0,09	disease	0,55	neutral	0,28	4	neutral	0,77	deleterious	0,62	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	-0,08	low_impact	-1,14	0,25	0,8	NA	NA	N	0,45	N	0,72	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5506	5506	T	G	MI.14945	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1037	346	I	S	aTc/aGc	-2,42	0	0	benign	0,01	neutral	0,16	neutral	4,07	neutral	-0,81	neutral	-2,29	neutral_impact	0	neutral	0,86	neutral	0,5	deleterious	2,5	19,48	0,13	0,4	disease	0,7	neutral	0,2	disease	0,56	neutral	0,41	2	neutral	0,84	deleterious	0,58	neutral	-6	neutral	0,18	medium_impact	1,03	medium_impact	-0,19	low_impact	-1,14	0,28	0,8	NA	NA	N	0,4	N	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5506	5506	T	A	MI.14946	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1037	346	I	N	aTc/aAc	-2,42	0	0	benign	0,06	neutral	0,09	neutral	4,04	neutral	-1,7	neutral	-2,19	neutral_impact	0	neutral	0,87	neutral	0,48	deleterious	2,88	21,8	0,13	0,4	disease	0,79	neutral	0,21	disease	0,6	neutral	0,45	1	neutral	0,9	deleterious	0,52	neutral	-6	neutral	0,26	medium_impact	0,3	medium_impact	-0,35	low_impact	-1,14	0,23	0,8	NA	NA	N	0,43	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5507	5507	C	G	MI.14947	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1038	346	I	M	atC/atG	-1,26	0	0	benign	0,03	neutral	0,23	neutral	4,08	neutral	-1,61	neutral	-0,23	neutral_impact	0	neutral	0,95	neutral	0,77	deleterious	0,46	7,14	0,17	0,45	neutral	0,42	neutral	0,04	neutral	0,26	neutral	0,21	6	neutral	0,76	deleterious	0,6	neutral	-6	neutral	0,13	medium_impact	0,59	medium_impact	-0,08	low_impact	-1,14	0,43	0,8	NA	NA	N	0,52	P	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5507	5507	C	A	MI.14948	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1038	346	I	M	atC/atA	-1,26	0	0	benign	0,03	neutral	0,23	neutral	4,08	neutral	-1,61	neutral	-0,23	neutral_impact	0	neutral	0,95	neutral	0,77	deleterious	0,88	9,95	0,17	0,45	neutral	0,42	neutral	0,04	neutral	0,26	neutral	0,21	6	neutral	0,76	deleterious	0,6	neutral	-6	neutral	0,13	medium_impact	0,59	medium_impact	-0,08	low_impact	-1,14	0,43	0,8	NA	NA	N	0,52	P	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5508	5508	T	A	MI.14949	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1039	347	L	M	Tta/Ata	-14,22	0	0	possibly_damaging	0,87	neutral	0,31	neutral	4,1	neutral	-1,83	neutral	-0,22	neutral_impact	0	neutral	0,95	neutral	0,9	neutral	1,65	14,14	0,12	0,4	NA	NA	neutral	0,04	neutral	0,18	neutral	0,11	8	neutral	0,89	neutral	0,22	neutral	-3	deleterious	0,71	low_impact	-1,55	medium_impact	0,02	low_impact	-1,14	0,5	0,8	NA	NA	P	0,6	P	0,3	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8390	8390	T	C	MI.1495	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	25	9	W	R	Tgg/Cgg	-3,57	0	0	probably_damaging	1	deleterious	0	deleterious	-1,63	deleterious	-12,89	deleterious	-13,96	high_impact	3,9	neutral	0,79	damaging	0,05	deleterious	3,38	22,9	0,21191278	0,85	disease	0,89	disease	0,56	disease	0,83	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,25	0,17	0,85	22,06	8,23	N	0,31	N	0,97	polymorphism	0,82	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5508	5508	T	G	MI.14950	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1039	347	L	V	Tta/Gta	-14,22	0	0	possibly_damaging	0,61	neutral	0,63	neutral	4,2	neutral	-0,35	neutral	-0,93	neutral_impact	0	neutral	0,87	neutral	0,71	deleterious	0,17	4,41	0,18	0,45	NA	NA	neutral	0,03	neutral	0,25	neutral	0,11	8	neutral	0,54	deleterious	0,51	neutral	-3	deleterious	0,45	medium_impact	-0,98	medium_impact	0,34	low_impact	-1,14	0,5	0,8	NA	NA	N	0,4	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5509	5509	T	G	MI.14951	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1040	347	L	W	tTa/tGa	-6,81	0	0	probably_damaging	0,96	neutral	0,18	neutral	4,06	deleterious	-3,86	neutral	-1,34	neutral_impact	0	neutral	0,81	neutral	0,44	deleterious	3,83	23,4	0,16	0,45	NA	NA	neutral	0,18	disease	0,61	neutral	0,26	5	neutral	0,97	neutral	0,11	neutral	-2	deleterious	0,85	low_impact	-2,06	medium_impact	-0,16	low_impact	-1,14	0,24	0,8	NA	NA	N	0,33	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5509	5509	T	C	MI.14952	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1040	347	L	S	tTa/tCa	-6,81	0	0	possibly_damaging	0,8	neutral	0,56	neutral	4,14	neutral	-0,9	neutral	0,39	neutral_impact	0	neutral	0,76	neutral	0,57	deleterious	3,58	23,2	0,19	0,45	NA	NA	neutral	0,15	disease	0,58	neutral	0,22	6	neutral	0,77	neutral	0,38	neutral	-3	deleterious	0,71	low_impact	-1,35	medium_impact	0,27	low_impact	-1,14	0,19	0,8	NA	NA	N	0,28	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5510	5510	A	T	MI.14953	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1041	347	L	F	ttA/ttT	-0,11	0	0	possibly_damaging	0,8	neutral	0,72	neutral	4,11	neutral	-1,52	neutral	-0,34	neutral_impact	0	neutral	0,91	neutral	0,55	neutral	1,58	13,74	0,18	0,45	NA	NA	neutral	0,11	disease	0,58	neutral	0,19	6	neutral	0,76	neutral	0,46	neutral	-3	deleterious	0,68	low_impact	-1,35	medium_impact	0,44	low_impact	-1,14	0,51	0,8	NA	NA	N	0,33	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5510	5510	A	C	MI.14954	MT-ND2	I	ENSG00000198763	ENSP00000355046	ENST00000361453	NU2M_HUMAN	P03891	4536	YP_003024027.1	1041	347	L	F	ttA/ttC	-0,11	0	0	possibly_damaging	0,8	neutral	0,72	neutral	4,11	neutral	-1,52	neutral	-0,34	neutral_impact	0	neutral	0,91	neutral	0,55	neutral	1,48	13,18	0,18	0,45	NA	NA	neutral	0,11	disease	0,58	neutral	0,19	6	neutral	0,76	neutral	0,46	neutral	-3	deleterious	0,68	low_impact	-1,35	medium_impact	0,44	low_impact	-1,14	0,51	0,8	NA	NA	N	0,33	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10059	10059	A	C	MI.14955	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	1	1	M	L	Ata/Cta	8,69	1	0	benign	0,32	deleterious	0	neutral	2,12	neutral	1,28	neutral	-2,34	NA	NA	neutral	0,68	neutral	0,56	neutral	1,05	10,93	0,05	0,35	NA	NA	neutral	0,36	neutral	0,28	neutral	0,2	6	deleterious	1	neutral	0,34	NA	0	neutral	0,39	NA	NA	NA	NA	NA	NA	0,5	0,8	1,74	8,66	P	0,65	P	0,44	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10059	10059	A	T	MI.14956	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	1	1	M	L	Ata/Tta	8,69	1	0	benign	0,32	deleterious	0	neutral	2,12	neutral	1,28	neutral	-2,34	NA	NA	neutral	0,68	neutral	0,56	neutral	1,14	11,41	0,05	0,35	NA	NA	neutral	0,36	neutral	0,28	neutral	0,2	6	deleterious	1	neutral	0,34	NA	0	neutral	0,39	NA	NA	NA	NA	NA	NA	0,5	0,8	1,74	8,66	P	0,66	P	0,44	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10059	10059	A	G	MI.14957	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	1	1	M	V	Ata/Gta	8,69	1	0	possibly_damaging	0,44	deleterious	0	neutral	2,02	neutral	0,83	deleterious	-3,03	NA	NA	neutral	0,65	neutral	0,6	deleterious	0,55	7,77	0,08	0,35	NA	NA	neutral	0,38	neutral	0,31	neutral	0,21	6	deleterious	1	neutral	0,28	deleterious	3	deleterious	0,45	NA	NA	NA	NA	NA	NA	0,27	0,8	1,74	8,66	P	0,63	P	0,43	NA	NA	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10060	10060	T	C	MI.14958	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	2	1	M	T	aTa/aCa	8,69	1	0	possibly_damaging	0,65	deleterious	0	neutral	1,92	neutral	-0,27	deleterious	-4,85	NA	NA	neutral	0,71	neutral	0,59	deleterious	0,76	9,2	0,06	0,35	NA	NA	neutral	0,48	disease	0,57	neutral	0,47	1	deleterious	1	neutral	0,18	deleterious	3	deleterious	0,69	NA	NA	NA	NA	NA	NA	0,11	0,8	1,74	8,66	P	0,62	P	0,62	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10060	10060	T	A	MI.14959	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	2	1	M	K	aTa/aAa	8,69	1	0	possibly_damaging	0,65	deleterious	0	neutral	1,92	neutral	-0,19	deleterious	-5,05	NA	NA	neutral	0,71	neutral	0,53	deleterious	1,84	15,24	0,05	0,35	NA	NA	disease	0,61	disease	0,52	disease	0,56	1	deleterious	1	neutral	0,18	deleterious	3	deleterious	0,69	NA	NA	NA	NA	NA	NA	0,21	0,8	1,74	8,66	P	0,61	P	0,92	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8390	8390	T	G	MI.1496	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	25	9	W	G	Tgg/Ggg	-3,57	0	0	probably_damaging	0,98	neutral	0,05	deleterious	-1,55	deleterious	-7,71	deleterious	-12,96	high_impact	3,9	neutral	0,84	damaging	0,09	deleterious	3,64	23,2	0,16637319	0,85	disease	0,85	neutral	0,42	disease	0,78	neutral	0,41	2	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,85	low_impact	-2,36	medium_impact	-0,43	high_impact	2,25	0,2	0,85	22,06	8,23	N	0,45	N	0,93	polymorphism	0,62	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10061	10061	A	T	MI.14960	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	3	1	M	I	atA/atT	7,53	1	0	possibly_damaging	0,53	deleterious	0	neutral	2,01	neutral	0,69	deleterious	-2,93	NA	NA	neutral	0,83	neutral	0,86	deleterious	0,02	2,81	0,07	0,35	NA	NA	neutral	0,38	neutral	0,25	neutral	0,2	6	deleterious	1	neutral	0,24	deleterious	3	deleterious	0,56	NA	NA	NA	NA	NA	NA	0,55	0,8	1,74	8,66	P	0,59	P	0,03	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10061	10061	A	C	MI.14961	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	3	1	M	I	atA/atC	7,53	1	0	possibly_damaging	0,53	deleterious	0	neutral	2,01	neutral	0,69	deleterious	-2,93	NA	NA	neutral	0,83	neutral	0,86	deleterious	-0,05	2,09	0,07	0,35	NA	NA	neutral	0,38	neutral	0,25	neutral	0,2	6	deleterious	1	neutral	0,24	deleterious	3	deleterious	0,56	NA	NA	NA	NA	NA	NA	0,55	0,8	1,74	8,66	P	0,59	P	0,03	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10062	10062	A	G	MI.14962	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	4	2	N	D	Aac/Gac	-3,11	0	0	possibly_damaging	0,9	neutral	0,2	neutral	1,93	neutral	-0,42	deleterious	-4,29	medium_impact	3,38	neutral	0,69	damaging	0,22	deleterious	3,5	23,1	0,43	0,55	NA	NA	neutral	0,42	neutral	0,38	neutral	0,19	6	neutral	0,94	neutral	0,15	NA	0	deleterious	0,72	low_impact	-1,58	medium_impact	-0,14	medium_impact	1,99	0,4	0,8	6,96	8,08	N	0,49	N	0,94	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10062	10062	A	C	MI.14963	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	4	2	N	H	Aac/Cac	-3,11	0	0	probably_damaging	0,98	neutral	0,54	neutral	1,86	neutral	-1,77	deleterious	-4,26	medium_impact	3,38	neutral	0,7	damaging	0,2	deleterious	2,77	21,2	0,3	0,45	NA	NA	neutral	0,48	neutral	0,34	neutral	0,33	3	deleterious	0,98	neutral	0,28	deleterious	1	deleterious	0,77	low_impact	-2,24	medium_impact	0,23	medium_impact	1,99	0,24	0,8	6,96	8,08	N	0,29	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10062	10062	A	T	MI.14964	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	4	2	N	Y	Aac/Tac	-3,11	0	0	probably_damaging	0,98	neutral	1	neutral	1,86	neutral	-1,42	deleterious	-6,55	medium_impact	2,83	neutral	0,71	damaging	0,2	deleterious	3,37	22,9	0,16	0,45	NA	NA	disease	0,59	neutral	0,49	neutral	0,49	0	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,79	low_impact	-2,24	high_impact	1,85	medium_impact	1,49	0,38	0,8	6,96	8,08	N	0,21	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10063	10063	A	T	MI.14965	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	5	2	N	I	aAc/aTc	8,69	1	0	probably_damaging	0,98	neutral	0,4	neutral	1,87	neutral	-0,8	deleterious	-7,04	medium_impact	3,04	neutral	0,72	damaging	0,21	deleterious	3,46	23	0,17	0,45	NA	NA	disease	0,7	neutral	0,21	neutral	0,48	0	deleterious	0,98	neutral	0,21	deleterious	1	deleterious	0,8	low_impact	-2,24	medium_impact	0,09	medium_impact	1,68	0,37	0,8	6,96	8,08	P	0,57	P	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10063	10063	A	G	MI.14966	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	5	2	N	S	aAc/aGc	8,69	1	0	possibly_damaging	0,9	neutral	0,4	neutral	1,94	neutral	0,07	deleterious	-4,17	medium_impact	2,02	neutral	0,77	neutral	0,37	deleterious	2,59	20,1	0,44	0,55	NA	NA	neutral	0,35	neutral	0,17	neutral	0,19	6	neutral	0,9	neutral	0,25	NA	0	deleterious	0,72	low_impact	-1,58	medium_impact	0,09	medium_impact	0,74	0,37	0,8	6,96	8,08	P	0,57	P	0,81	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10063	10063	A	C	MI.14967	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	5	2	N	T	aAc/aCc	8,69	1	0	probably_damaging	0,94	neutral	0,39	neutral	1,91	neutral	-0,31	deleterious	-4,79	medium_impact	2,48	neutral	0,84	neutral	0,34	deleterious	2,92	21,9	0,28	0,45	NA	NA	neutral	0,41	neutral	0,15	neutral	0,2	6	neutral	0,94	neutral	0,23	deleterious	1	deleterious	0,74	low_impact	-1,8	medium_impact	0,08	medium_impact	1,17	0,31	0,8	6,96	8,08	P	0,54	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10064	10064	C	G	MI.14968	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	6	2	N	K	aaC/aaG	6,38	1	0	probably_damaging	0,94	neutral	0,29	neutral	1,95	neutral	-0,13	deleterious	-5,08	medium_impact	2,83	neutral	0,65	damaging	0,21	deleterious	3,71	23,3	0,42	0,5	NA	NA	disease	0,58	neutral	0,4	neutral	0,46	1	neutral	0,95	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-1,8	medium_impact	-0,03	medium_impact	1,49	0,46	0,8	6,96	8,08	P	0,6	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10064	10064	C	A	MI.14969	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	6	2	N	K	aaC/aaA	6,38	1	0	probably_damaging	0,94	neutral	0,29	neutral	1,95	neutral	-0,13	deleterious	-5,08	medium_impact	2,83	neutral	0,65	damaging	0,21	deleterious	4,12	23,8	0,42	0,5	NA	NA	disease	0,58	neutral	0,4	neutral	0,46	1	neutral	0,95	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-1,8	medium_impact	-0,03	medium_impact	1,49	0,46	0,8	6,96	8,08	P	0,6	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8391	8391	G	C	MI.1497	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	26	9	W	S	tGg/tCg	7,53	1	0	probably_damaging	0,99	deleterious	0,02	deleterious	-1,63	deleterious	-12,18	deleterious	-13,95	high_impact	3,9	neutral	0,86	damaging	0,07	deleterious	3,83	23,4	0,15456258	0,85	disease	0,88	disease	0,54	disease	0,78	disease	0,68	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,87	low_impact	-2,65	medium_impact	-0,66	high_impact	2,25	0,16	0,85	22,06	8,23	P	0,58	P	0,95	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10065	10065	T	G	MI.14970	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	7	3	F	V	Ttc/Gtc	-1,26	0	0	possibly_damaging	0,9	neutral	0,33	neutral	1,98	neutral	-0,93	neutral	0,92	neutral_impact	0,06	neutral	0,91	neutral	0,92	deleterious	3,84	23,4	0,14	0,4	NA	NA	neutral	0,24	neutral	0,3	neutral	0,19	6	neutral	0,91	neutral	0,22	neutral	-3	deleterious	0,62	low_impact	-1,58	medium_impact	0,02	low_impact	-1,05	0,28	0,8	5,22	8,44	N	0,5	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10065	10065	T	C	MI.14971	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	7	3	F	L	Ttc/Ctc	-1,26	0	0	possibly_damaging	0,85	neutral	1	neutral	2,13	neutral	-0,14	neutral	2,44	neutral_impact	-1,7	neutral	0,96	neutral	1	neutral	1,17	11,57	0,21	0,45	NA	NA	neutral	0,05	neutral	0,18	neutral	0,16	7	neutral	0,85	deleterious	0,58	neutral	-3	deleterious	0,58	low_impact	-1,4	high_impact	1,85	low_impact	-2,67	0,5	0,8	5,22	8,44	N	0,29	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10065	10065	T	A	MI.14972	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	7	3	F	I	Ttc/Atc	-1,26	0	0	possibly_damaging	0,9	neutral	0,39	neutral	1,98	neutral	-0,99	neutral	1,46	neutral_impact	0,06	neutral	0,95	neutral	0,98	deleterious	3,14	22,6	0,17	0,45	NA	NA	neutral	0,17	neutral	0,2	neutral	0,22	6	neutral	0,9	neutral	0,25	neutral	-3	deleterious	0,62	low_impact	-1,58	medium_impact	0,08	low_impact	-1,05	0,58	0,8	5,22	8,44	N	0,46	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10066	10066	T	G	MI.14973	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	8	3	F	C	tTc/tGc	-1,49	0	0	probably_damaging	0,98	neutral	0,08	neutral	1,85	deleterious	-3,77	neutral	-0,97	low_impact	1,04	neutral	0,79	neutral	0,59	deleterious	3,9	23,5	0,08	0,35	NA	NA	neutral	0,34	disease	0,52	neutral	0,25	5	deleterious	0,99	neutral	0,05	neutral	-2	deleterious	0,67	low_impact	-2,24	medium_impact	-0,4	medium_impact	-0,16	0,15	0,8	5,22	8,44	N	0,39	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10066	10066	T	A	MI.14974	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	8	3	F	Y	tTc/tAc	-1,49	0	0	possibly_damaging	0,85	neutral	0,59	neutral	1,9	neutral	-0,85	neutral	-0,85	low_impact	1,04	neutral	0,81	neutral	0,68	deleterious	4,03	23,6	0,18	0,45	NA	NA	neutral	0,17	disease	0,51	neutral	0,23	5	neutral	0,82	neutral	0,37	neutral	-3	deleterious	0,62	low_impact	-1,4	medium_impact	0,28	medium_impact	-0,16	0,51	0,8	5,22	8,44	N	0,35	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10066	10066	T	C	MI.14975	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	8	3	F	S	tTc/tCc	-1,49	0	0	probably_damaging	0,94	neutral	0,45	neutral	1,9	neutral	-1,91	neutral	-1,35	neutral_impact	-0,12	neutral	0,83	neutral	0,79	deleterious	4,01	23,6	0,06	0,35	NA	NA	neutral	0,23	neutral	0,5	neutral	0,17	7	neutral	0,94	neutral	0,26	neutral	-2	deleterious	0,66	low_impact	-1,8	medium_impact	0,14	low_impact	-1,22	0,2	0,8	5,22	8,44	N	0,32	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10067	10067	C	G	MI.14976	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	9	3	F	L	ttC/ttG	2,44	0,05	0	possibly_damaging	0,85	neutral	1	neutral	2,13	neutral	-0,14	neutral	2,44	neutral_impact	-1,7	neutral	0,96	neutral	1	neutral	1,38	12,7	0,21	0,45	NA	NA	neutral	0,05	neutral	0,18	neutral	0,16	7	neutral	0,85	deleterious	0,58	neutral	-3	deleterious	0,58	low_impact	-1,4	high_impact	1,85	low_impact	-2,67	0,5	0,8	5,22	8,44	N	0,32	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10067	10067	C	A	MI.14977	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	9	3	F	L	ttC/ttA	2,44	0,05	0	possibly_damaging	0,85	neutral	1	neutral	2,13	neutral	-0,14	neutral	2,44	neutral_impact	-1,7	neutral	0,96	neutral	1	neutral	1,71	14,47	0,21	0,45	NA	NA	neutral	0,05	neutral	0,18	neutral	0,16	7	neutral	0,85	deleterious	0,58	neutral	-3	deleterious	0,58	low_impact	-1,4	high_impact	1,85	low_impact	-2,67	0,5	0,8	5,22	8,44	N	0,32	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10068	10068	G	A	MI.14978	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	10	4	A	T	Gcc/Acc	-2,65	0	0	benign	0	neutral	0,26	neutral	1,97	neutral	-0,46	neutral	0,09	neutral_impact	0,24	neutral	0,97	neutral	0,95	deleterious	0,65	8,51	0,25	0,45	NA	NA	neutral	0,07	neutral	0,25	neutral	0,19	6	neutral	0,74	deleterious	0,63	neutral	-6	neutral	0,07	medium_impact	1,99	medium_impact	-0,06	medium_impact	-0,89	0,71	0,85	14,78	10,28	P	0,55	P	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10068	10068	G	C	MI.14979	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	10	4	A	P	Gcc/Ccc	-2,65	0	0	benign	0,02	neutral	0,11	neutral	1,88	neutral	-2,18	neutral	-1,32	low_impact	1,18	neutral	0,93	neutral	0,83	deleterious	0,6	8,18	0,06	0,35	NA	NA	neutral	0,45	neutral	0,46	neutral	0,19	6	neutral	0,89	deleterious	0,55	neutral	-6	neutral	0,19	medium_impact	0,81	medium_impact	-0,31	medium_impact	-0,03	0,44	0,8	14,78	10,28	N	0,45	N	0,25	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8391	8391	G	T	MI.1498	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	26	9	W	L	tGg/tTg	7,53	1	0	probably_damaging	0,98	neutral	0,09	deleterious	-1,63	deleterious	-12,59	deleterious	-12,95	high_impact	3,56	neutral	0,86	damaging	0,06	deleterious	4,03	23,6	0,17443806	0,85	disease	0,79	neutral	0,42	disease	0,77	neutral	0,41	2	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,83	low_impact	-2,36	medium_impact	-0,28	medium_impact	1,95	0,17	0,85	22,06	8,23	P	0,58	P	0,96	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10068	10068	G	T	MI.14980	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	10	4	A	S	Gcc/Tcc	-2,65	0	0	benign	0	neutral	0,15	neutral	1,94	neutral	-0,57	neutral	-0,69	neutral_impact	0,62	neutral	0,89	neutral	0,82	deleterious	0,06	3,23	0,32	0,5	NA	NA	neutral	0,08	neutral	0,28	neutral	0,21	6	neutral	0,85	deleterious	0,58	neutral	-6	neutral	0,1	medium_impact	1,99	medium_impact	-0,23	medium_impact	-0,54	0,3	0,8	14,78	10,28	P	0,57	P	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10069	10069	C	T	MI.14981	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	11	4	A	V	gCc/gTc	-3,11	0	0	benign	0	neutral	0,29	neutral	2,02	neutral	-0,1	neutral	1,5	neutral_impact	0,66	neutral	0,99	neutral	0,97	deleterious	0,43	6,91	0,18	0,45	NA	NA	neutral	0,1	neutral	0,29	neutral	0,2	6	neutral	0,71	deleterious	0,65	neutral	-6	neutral	0,07	medium_impact	1,99	medium_impact	-0,03	medium_impact	-0,5	0,75	0,85	14,78	10,28	N	0,47	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10069	10069	C	A	MI.14982	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	11	4	A	D	gCc/gAc	-3,11	0	0	benign	0,02	neutral	0,07	neutral	1,89	neutral	-1,74	neutral	-2,3	medium_impact	1,98	neutral	0,84	neutral	0,61	deleterious	2,58	19,95	0,05	0,35	NA	NA	neutral	0,38	disease	0,66	neutral	0,31	4	neutral	0,93	deleterious	0,53	neutral	-3	neutral	0,16	medium_impact	0,81	medium_impact	-0,43	medium_impact	0,71	0,23	0,8	14,78	10,28	N	0,4	N	0,37	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10069	10069	C	G	MI.14983	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	11	4	A	G	gCc/gGc	-3,11	0	0	benign	0	neutral	0,08	neutral	1,9	neutral	-1,51	neutral	-2,42	low_impact	1,63	neutral	0,87	neutral	0,73	neutral	0,96	10,43	0,3	0,45	NA	NA	neutral	0,14	neutral	0,5	neutral	0,25	5	neutral	0,92	deleterious	0,54	neutral	-6	neutral	0,09	medium_impact	1,99	medium_impact	-0,4	medium_impact	0,39	0,51	0,8	14,78	10,28	N	0,5	N	0,31	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10071	10071	T	G	MI.14984	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	13	5	L	V	Tta/Gta	-3,8	0	0	possibly_damaging	0,9	neutral	0,52	neutral	1,89	neutral	-0,66	neutral	-1,05	low_impact	1,78	neutral	0,92	neutral	0,94	deleterious	2,07	16,63	0,27	0,45	NA	NA	neutral	0,19	neutral	0,32	neutral	0,22	6	neutral	0,89	neutral	0,31	neutral	-3	deleterious	0,65	low_impact	-1,58	medium_impact	0,21	medium_impact	0,52	0,64	0,8	4,35	7,91	N	0,4	N	0,14	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10071	10071	T	A	MI.14985	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	13	5	L	M	Tta/Ata	-3,8	0	0	probably_damaging	0,98	neutral	0,39	neutral	1,8	neutral	-2,14	neutral	-0,92	low_impact	1,26	neutral	0,93	neutral	0,97	deleterious	2,09	16,77	0,24	0,45	NA	NA	neutral	0,09	neutral	0,3	neutral	0,26	5	deleterious	0,98	neutral	0,21	neutral	-2	deleterious	0,65	low_impact	-2,24	medium_impact	0,08	medium_impact	0,05	0,61	0,8	4,35	7,91	N	0,5	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10072	10072	T	C	MI.14986	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	14	5	L	S	tTa/tCa	-6,35	0	0	probably_damaging	0,96	neutral	0,25	neutral	1,78	neutral	-2,81	deleterious	-3,69	medium_impact	1,98	neutral	0,76	neutral	0,43	deleterious	3,59	23,2	0,05	0,35	NA	NA	neutral	0,34	neutral	0,41	neutral	0,17	7	neutral	0,97	neutral	0,15	deleterious	1	deleterious	0,72	low_impact	-1,96	medium_impact	-0,08	medium_impact	0,71	0,33	0,8	4,35	7,91	N	0,36	N	0,65	polymorphism	1	0,1	.	.	.	.	.	.	COSM1331643	.	.	.	.	.	.	.	.
chrM	10072	10072	T	G	MI.14987	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	14	5	L	W	tTa/tGa	-6,35	0	0	probably_damaging	0,99	neutral	0,11	neutral	1,72	deleterious	-5,23	deleterious	-4,48	medium_impact	3,33	neutral	0,74	damaging	0,16	deleterious	3,64	23,2	0,06	0,35	NA	NA	neutral	0,48	disease	0,64	disease	0,52	0	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,73	low_impact	-2,52	medium_impact	-0,31	medium_impact	1,94	0,27	0,8	4,35	7,91	N	0,35	N	0,86	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10073	10073	A	T	MI.14988	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	15	5	L	F	ttA/ttT	-0,1	0	0	probably_damaging	0,96	neutral	0,68	neutral	1,79	neutral	-2,29	deleterious	-2,62	low_impact	1,54	neutral	0,89	neutral	0,6	deleterious	2,42	18,93	0,21	0,45	NA	NA	neutral	0,32	neutral	0,36	neutral	0,18	6	neutral	0,96	neutral	0,36	neutral	-2	deleterious	0,69	low_impact	-1,96	medium_impact	0,37	medium_impact	0,3	0,71	0,85	4,35	7,91	N	0,3	N	0,35	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10073	10073	A	C	MI.14989	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	15	5	L	F	ttA/ttC	-0,1	0	0	probably_damaging	0,96	neutral	0,68	neutral	1,79	neutral	-2,29	deleterious	-2,62	low_impact	1,54	neutral	0,89	neutral	0,6	deleterious	2,27	17,99	0,21	0,45	NA	NA	neutral	0,32	neutral	0,36	neutral	0,18	6	neutral	0,96	neutral	0,36	neutral	-2	deleterious	0,69	low_impact	-1,96	medium_impact	0,37	medium_impact	0,3	0,71	0,85	4,35	7,91	N	0,3	N	0,35	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8392	8392	G	C	MI.1499	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	27	9	W	C	tgG/tgC	9,15	1	0,01	probably_damaging	1	deleterious	0	deleterious	-1,63	deleterious	-13,64	deleterious	-12,96	high_impact	3,9	neutral	0,84	damaging	0,05	deleterious	3,76	23,3	0,21080113	0,85	disease	0,94	neutral	0,5	disease	0,8	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,6	low_impact	-1,4	high_impact	2,25	0,17	0,85	22,06	8,23	P	0,56	P	0,92	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10074	10074	A	C	MI.14990	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	16	6	I	L	Att/Ctt	-6,12	0	0	benign	0	neutral	0,93	neutral	2,02	neutral	0,32	neutral	-0,23	neutral_impact	0,64	neutral	0,82	neutral	0,71	deleterious	0,57	7,98	0,2	0,45	neutral	0,15	neutral	0,28	neutral	0,29	neutral	0,44	1	neutral	0,06	deleterious	0,97	neutral	-6	neutral	0,08	medium_impact	1,99	medium_impact	0,81	medium_impact	-0,52	0,39	0,8	11,3	8,73	N	0,28	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10074	10074	A	T	MI.14991	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	16	6	I	F	Att/Ttt	-6,12	0	0	benign	0,04	neutral	0,63	neutral	1,95	neutral	-0,26	neutral	-1,21	neutral_impact	-0,04	neutral	0,82	neutral	0,8	deleterious	0,61	8,24	0,16	0,45	neutral	0,3	neutral	0,34	neutral	0,37	neutral	0,45	1	neutral	0,32	deleterious	0,8	neutral	-6	neutral	0,18	medium_impact	0,53	medium_impact	0,32	low_impact	-1,15	0,46	0,8	11,3	8,73	N	0,28	N	0,31	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10074	10074	A	G	MI.14992	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	16	6	I	V	Att/Gtt	-6,12	0	0	benign	0	neutral	0,34	neutral	1,99	neutral	-0,1	neutral	0,4	low_impact	1,01	neutral	0,93	neutral	0,96	neutral	-1,24	0,01	0,27	0,45	neutral	0,15	neutral	0,08	neutral	0,33	neutral	0,28	5	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,06	medium_impact	1,99	medium_impact	0,03	medium_impact	-0,18	0,3	0,8	11,3	8,73	N	0,44	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10075	10075	T	C	MI.14993	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	17	6	I	T	aTt/aCt	-1,03	0	0	benign	0,01	neutral	0,7	neutral	1,9	neutral	-1,29	neutral	1,83	neutral_impact	-0,38	neutral	0,95	neutral	1	neutral	-1,14	0,01	0,11	0,4	neutral	0,15	neutral	0,15	neutral	0,35	neutral	0,27	5	neutral	0,28	deleterious	0,85	neutral	-6	neutral	0,1	medium_impact	1,09	medium_impact	0,39	low_impact	-1,46	0,26	0,8	11,3	8,73	N	0,26	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10075	10075	T	G	MI.14994	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	17	6	I	S	aTt/aGt	-1,03	0	0	benign	0,01	neutral	0,49	neutral	1,87	neutral	-1,66	neutral	1,19	neutral_impact	0,72	neutral	0,92	neutral	0,94	neutral	0,93	10,25	0,06	0,35	neutral	0,24	neutral	0,43	neutral	0,41	neutral	0,46	1	neutral	0,5	deleterious	0,74	neutral	-6	neutral	0,12	medium_impact	1,09	medium_impact	0,18	medium_impact	-0,45	0,28	0,8	11,3	8,73	N	0,34	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10075	10075	T	A	MI.14995	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	17	6	I	N	aTt/aAt	-1,03	0	0	benign	0,06	neutral	0,1	neutral	1,83	neutral	-2,76	neutral	-0,5	low_impact	1,62	neutral	0,74	neutral	0,4	deleterious	2,68	20,7	0,1	0,4	neutral	0,2	disease	0,53	disease	0,54	disease	0,69	4	neutral	0,89	deleterious	0,52	neutral	-6	neutral	0,19	medium_impact	0,36	medium_impact	-0,34	medium_impact	0,38	0,29	0,8	11,3	8,73	N	0,42	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10076	10076	T	G	MI.14996	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	18	6	I	M	atT/atG	0,36	0	0	benign	0,1	neutral	0,6	neutral	1,89	neutral	-1,43	neutral	0,02	neutral_impact	0,19	neutral	0,89	neutral	0,91	neutral	-0,29	0,7	0,22	0,45	neutral	0,19	neutral	0,09	neutral	0,21	neutral	0,26	5	neutral	0,31	deleterious	0,75	neutral	-6	neutral	0,31	medium_impact	0,15	medium_impact	0,29	medium_impact	-0,93	0,46	0,8	11,3	8,73	N	0,39	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10076	10076	T	A	MI.14997	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	18	6	I	M	atT/atA	0,36	0	0	benign	0,1	neutral	0,6	neutral	1,89	neutral	-1,43	neutral	0,02	neutral_impact	0,19	neutral	0,89	neutral	0,91	deleterious	0,08	3,41	0,22	0,45	neutral	0,19	neutral	0,09	neutral	0,21	neutral	0,26	5	neutral	0,31	deleterious	0,75	neutral	-6	neutral	0,31	medium_impact	0,15	medium_impact	0,29	medium_impact	-0,93	0,46	0,8	11,3	8,73	N	0,38	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10077	10077	T	A	MI.14998	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	19	7	L	M	Tta/Ata	-20	0	0	probably_damaging	0,98	neutral	0,51	neutral	1,69	deleterious	-3	neutral	-1,14	low_impact	1,94	neutral	0,87	neutral	0,93	deleterious	2,32	18,32	0,27	0,45	neutral	0,4	neutral	0,14	neutral	0,39	neutral	0,32	4	deleterious	0,98	neutral	0,27	neutral	-2	deleterious	0,63	low_impact	-2,24	medium_impact	0,2	medium_impact	0,67	0,48	0,8	2,61	9,21	N	0,39	N	0,57	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10077	10077	T	G	MI.14999	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	19	7	L	V	Tta/Gta	-20	0	0	possibly_damaging	0,9	neutral	0,47	neutral	1,78	neutral	-1,23	neutral	-1,76	low_impact	1,94	neutral	0,87	neutral	0,78	deleterious	2,26	17,89	0,21	0,45	neutral	0,33	neutral	0,27	neutral	0,39	neutral	0,45	1	neutral	0,89	neutral	0,29	neutral	-3	deleterious	0,62	low_impact	-1,58	medium_impact	0,16	medium_impact	0,67	0,51	0,8	2,61	9,21	N	0,35	N	0,53	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8533	8533	G	C	MI.15	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	7	3	E	Q	Gaa/Caa	-0,1	0,06	0	probably_damaging	0,97	neutral	0,34	neutral	4,66	neutral	-0,83	neutral	-0,94	low_impact	1,61	neutral	0,92	neutral	0,68	neutral	1,32	12,35	0,68	0,75	neutral	0,28	neutral	0,1	neutral	0,11	neutral	0,34	3	neutral	0,97	neutral	0,19	neutral	-2	deleterious	0,6	low_impact	-2,19	medium_impact	0,13	medium_impact	0,28	0,86	0,9	15,93	14,48	P	0,56	P	0,89	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8596	8596	A	C	MI.150	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	70	24	I	L	Att/Ctt	-7,51	0	0	probably_damaging	0,93	neutral	1	neutral	4,06	neutral	-1,62	neutral	-0,73	neutral_impact	-0,51	neutral	0,83	neutral	0,81	neutral	1,18	11,64	0,35	0,65	neutral	0,24	neutral	0,12	neutral	0,25	neutral	0,26	5	neutral	0,93	deleterious	0,54	neutral	-2	deleterious	0,58	low_impact	-1,82	high_impact	1,98	low_impact	-1,54	0,52	0,9	18,14	17,22	N	0,25	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8392	8392	G	T	MI.1500	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	27	9	W	C	tgG/tgT	9,15	1	0,01	probably_damaging	1	deleterious	0	deleterious	-1,63	deleterious	-13,64	deleterious	-12,96	high_impact	3,9	neutral	0,84	damaging	0,05	deleterious	3,93	23,5	0,21080113	0,85	disease	0,94	neutral	0,5	disease	0,8	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,6	low_impact	-1,4	high_impact	2,25	0,17	0,85	22,06	8,23	P	0,56	P	0,92	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10078	10078	T	G	MI.15000	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	20	7	L	W	tTa/tGa	-2,42	0	0	probably_damaging	0,99	neutral	0,05	neutral	1,61	deleterious	-5,8	deleterious	-4,78	high_impact	3,83	neutral	0,76	damaging	0,06	deleterious	3,66	23,2	0,05	0,35	disease	0,84	disease	0,62	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,76	low_impact	-2,52	medium_impact	-0,52	high_impact	2,4	0,2	0,8	2,61	9,21	N	0,34	N	0,95	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10078	10078	T	C	MI.15001	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	20	7	L	S	tTa/tCa	-2,42	0	0	probably_damaging	0,96	neutral	0,54	neutral	1,65	deleterious	-3,49	deleterious	-4,61	medium_impact	2,47	neutral	0,76	damaging	0,1	deleterious	3,69	23,3	0,04	0,35	disease	0,71	neutral	0,49	disease	0,65	disease	0,66	3	neutral	0,96	neutral	0,29	deleterious	1	deleterious	0,74	low_impact	-1,96	medium_impact	0,23	medium_impact	1,16	0,24	0,8	2,61	9,21	N	0,21	N	0,88	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10079	10079	A	T	MI.15002	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	21	7	L	F	ttA/ttT	3,6	0,28	0	probably_damaging	0,96	neutral	0,39	neutral	1,7	neutral	-2,69	deleterious	-2,85	low_impact	1,87	neutral	0,81	neutral	0,47	deleterious	2,22	17,66	0,16	0,45	neutral	0,27	neutral	0,37	neutral	0,43	neutral	0,46	1	neutral	0,96	neutral	0,22	neutral	-2	deleterious	0,65	low_impact	-1,96	medium_impact	0,08	medium_impact	0,61	0,53	0,8	2,61	9,21	N	0,38	N	0,76	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10079	10079	A	C	MI.15003	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	21	7	L	F	ttA/ttC	3,6	0,28	0	probably_damaging	0,96	neutral	0,39	neutral	1,7	neutral	-2,69	deleterious	-2,85	low_impact	1,87	neutral	0,81	neutral	0,47	deleterious	2,08	16,72	0,16	0,45	neutral	0,27	neutral	0,37	neutral	0,43	neutral	0,46	1	neutral	0,96	neutral	0,22	neutral	-2	deleterious	0,65	low_impact	-1,96	medium_impact	0,08	medium_impact	0,61	0,53	0,8	2,61	9,21	N	0,37	N	0,76	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10080	10080	A	T	MI.15004	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	22	8	M	L	Ata/Tta	-5,42	0	0	benign	0	neutral	1	neutral	2,11	neutral	1,59	neutral	0,2	neutral_impact	-0,3	neutral	0,89	neutral	0,99	neutral	-1,48	0	0,22	0,45	neutral	0,08	neutral	0,24	neutral	0,34	neutral	0,4	2	neutral	0	deleterious	1	neutral	-6	neutral	0,07	medium_impact	1,99	high_impact	1,85	low_impact	-1,38	0,28	0,8	18,26	8,78	N	0,35	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10080	10080	A	G	MI.15005	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	22	8	M	V	Ata/Gta	-5,42	0	0	benign	0	neutral	0,53	neutral	2,05	neutral	1,2	neutral	-0,96	low_impact	0,88	neutral	0,93	neutral	0,86	neutral	-0,69	0,08	0,25	0,45	neutral	0,11	neutral	0,3	neutral	0,39	neutral	0,43	1	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,08	medium_impact	1,99	medium_impact	0,22	medium_impact	-0,3	0,27	0,8	18,26	8,78	N	0,34	N	0,27	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10080	10080	A	C	MI.15006	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	22	8	M	L	Ata/Cta	-5,42	0	0	benign	0	neutral	1	neutral	2,11	neutral	1,59	neutral	0,2	neutral_impact	-0,3	neutral	0,89	neutral	0,99	neutral	-1,54	0	0,22	0,45	neutral	0,08	neutral	0,24	neutral	0,34	neutral	0,4	2	neutral	0	deleterious	1	neutral	-6	neutral	0,07	medium_impact	1,99	high_impact	1,85	low_impact	-1,38	0,28	0,8	18,26	8,78	N	0,35	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10081	10081	T	A	MI.15007	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	23	8	M	K	aTa/aAa	-8,89	0	0	benign	0	neutral	0,12	neutral	1,91	neutral	-0,94	deleterious	-3,17	medium_impact	2,67	neutral	0,81	neutral	0,46	deleterious	1,87	15,42	0,05	0,35	neutral	0,3	disease	0,7	disease	0,71	disease	0,77	5	neutral	0,88	deleterious	0,56	neutral	-3	neutral	0,18	medium_impact	1,99	medium_impact	-0,29	medium_impact	1,34	0,23	0,8	18,26	8,78	N	0,35	N	0,65	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10081	10081	T	C	MI.15008	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	23	8	M	T	aTa/aCa	-8,89	0	0	benign	0	neutral	0,43	neutral	1,97	neutral	0,07	neutral	-1,71	neutral_impact	-0,09	neutral	0,95	neutral	0,98	neutral	-1	0,02	0,12	0,4	neutral	0,14	neutral	0,2	neutral	0,39	neutral	0,34	3	neutral	0,57	deleterious	0,72	neutral	-6	neutral	0,1	medium_impact	1,99	medium_impact	0,12	low_impact	-1,19	0,15	0,8	18,26	8,78	N	0,34	N	0,01	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10082	10082	A	T	MI.15009	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	24	8	M	I	atA/atT	1,29	0	0	benign	0	neutral	0,91	neutral	2,06	neutral	1,08	neutral	-0,59	neutral_impact	0,29	neutral	0,93	neutral	0,98	neutral	-0,39	0,42	0,22	0,45	neutral	0,08	neutral	0,26	neutral	0,34	neutral	0,4	2	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,08	medium_impact	1,99	medium_impact	0,75	medium_impact	-0,84	0,2	0,8	18,26	8,78	N	0,34	N	0,21	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8393	8393	C	G	MI.1501	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	28	10	P	A	Ccc/Gcc	2,67	0,98	0,02	probably_damaging	0,99	neutral	0,05	neutral	2,03	neutral	0,86	neutral	-1,15	medium_impact	2,1	neutral	0,99	neutral	0,75	neutral	1,43	12,96	0,5726291	0,85	neutral	0,21	neutral	0,08	neutral	0,45	neutral	0,05	9	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,7	low_impact	-2,65	medium_impact	-0,43	medium_impact	0,7	0,71	0,85	NA	NA	P	0,6	P	0,4	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10082	10082	A	C	MI.15010	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	24	8	M	I	atA/atC	1,29	0	0	benign	0	neutral	0,91	neutral	2,06	neutral	1,08	neutral	-0,59	neutral_impact	0,29	neutral	0,93	neutral	0,98	neutral	-0,45	0,3	0,22	0,45	neutral	0,08	neutral	0,26	neutral	0,34	neutral	0,4	2	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,08	medium_impact	1,99	medium_impact	0,75	medium_impact	-0,84	0,2	0,8	18,26	8,78	N	0,34	N	0,21	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10083	10083	A	C	MI.15011	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	25	9	I	L	Atc/Ctc	-14,45	0	0	benign	0	neutral	1	neutral	1,9	neutral	-0,85	neutral	-1,1	low_impact	1,44	neutral	0,72	neutral	0,73	deleterious	0,59	8,09	0,23	0,45	neutral	0,18	neutral	0,44	neutral	0,34	neutral	0,45	1	neutral	0	deleterious	1	neutral	-6	neutral	0,08	medium_impact	1,99	high_impact	1,85	medium_impact	0,21	0,38	0,8	5,22	7,3	N	0,33	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10083	10083	A	G	MI.15012	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	25	9	I	V	Atc/Gtc	-14,45	0	0	benign	0	neutral	0,26	neutral	1,94	neutral	-0,17	neutral	-0,18	low_impact	0,83	neutral	0,92	neutral	0,96	neutral	-0,33	0,56	0,33	0,5	neutral	0,16	neutral	0,24	neutral	0,36	neutral	0,43	1	neutral	0,74	deleterious	0,63	neutral	-6	neutral	0,06	medium_impact	1,99	medium_impact	-0,06	medium_impact	-0,35	0,26	0,8	5,22	7,3	N	0,42	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10083	10083	A	T	MI.15013	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	25	9	I	F	Atc/Ttc	-14,45	0	0	benign	0,02	neutral	0,55	neutral	1,77	neutral	-2,07	deleterious	-2,59	low_impact	1,44	neutral	0,68	neutral	0,67	neutral	1,57	13,7	0,18	0,45	neutral	0,47	disease	0,63	neutral	0,42	disease	0,51	0	neutral	0,42	deleterious	0,77	neutral	-6	neutral	0,16	medium_impact	0,81	medium_impact	0,24	medium_impact	0,21	0,36	0,8	5,22	7,3	N	0,33	N	0,48	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10084	10084	T	G	MI.15014	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	26	9	I	S	aTc/aGc	-0,1	0	0,03	benign	0,01	neutral	0,21	neutral	1,74	neutral	-2,66	deleterious	-2,78	medium_impact	2,63	neutral	0,65	neutral	0,38	deleterious	2,11	16,93	0,07	0,35	neutral	0,49	disease	0,71	disease	0,56	disease	0,67	3	neutral	0,79	deleterious	0,6	neutral	-3	neutral	0,16	medium_impact	1,09	medium_impact	-0,13	medium_impact	1,3	0,26	0,8	5,22	7,3	N	0,35	N	0,47	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10084	10084	T	A	MI.15015	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	26	9	I	N	aTc/aAc	-0,1	0	0,03	benign	0,01	deleterious	0,03	neutral	1,71	deleterious	-3,82	deleterious	-3,74	high_impact	3,61	damaging	0,6	neutral	0,36	deleterious	2,4	18,83	0,1	0,4	disease	0,65	disease	0,71	disease	0,64	disease	0,69	4	neutral	0,97	deleterious	0,51	deleterious	2	neutral	0,2	medium_impact	1,09	medium_impact	-0,65	high_impact	2,2	0,3	0,8	5,22	7,3	N	0,34	N	0,53	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10084	10084	T	C	MI.15016	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	26	9	I	T	aTc/aCc	-0,1	0	0,03	benign	0	neutral	0,35	neutral	1,78	neutral	-2,15	neutral	-0,96	low_impact	1,3	neutral	0,92	neutral	0,98	neutral	-0,28	0,72	0,15	0,4	neutral	0,18	neutral	0,34	neutral	0,4	neutral	0,44	1	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,1	medium_impact	1,99	medium_impact	0,04	medium_impact	0,08	0,31	0,8	5,22	7,3	N	0,37	N	0,12	polymorphism	1	0,04	rs41487950	Likely benign	not_provided	RCV000224206.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	10085	10085	C	G	MI.15017	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	27	9	I	M	atC/atG	-0,57	0	0	benign	0,05	neutral	0,37	neutral	1,75	neutral	-2,6	neutral	-1,61	low_impact	1,8	neutral	0,8	neutral	0,9	neutral	1,14	11,45	0,29	0,45	neutral	0,44	neutral	0,46	neutral	0,35	neutral	0,47	1	neutral	0,6	deleterious	0,66	neutral	-6	neutral	0,13	medium_impact	0,44	medium_impact	0,06	medium_impact	0,54	0,39	0,8	5,22	7,3	N	0,39	N	0,6	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10085	10085	C	A	MI.15018	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	27	9	I	M	atC/atA	-0,57	0	0	benign	0,05	neutral	0,37	neutral	1,75	neutral	-2,6	neutral	-1,61	low_impact	1,8	neutral	0,8	neutral	0,9	neutral	1,6	13,87	0,29	0,45	neutral	0,44	neutral	0,46	neutral	0,35	neutral	0,47	1	neutral	0,6	deleterious	0,66	neutral	-6	neutral	0,13	medium_impact	0,44	medium_impact	0,06	medium_impact	0,54	0,39	0,8	5,22	7,3	N	0,39	N	0,6	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10086	10086	A	T	MI.15019	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	28	10	N	Y	Aac/Tac	-10,98	0	0	probably_damaging	0,98	neutral	0,15	neutral	1,97	neutral	-0,47	deleterious	-6,14	medium_impact	2,34	neutral	0,84	neutral	0,39	deleterious	3,44	23	0,14	0,4	neutral	0,45	disease	0,75	neutral	0,5	disease	0,62	2	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,68	low_impact	-2,24	medium_impact	-0,23	medium_impact	1,04	0,33	0,8	1,74	7,74	N	0,34	N	0,99	polymorphism	1	0,11	rs28358274	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8393	8393	C	A	MI.1502	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	28	10	P	T	Ccc/Acc	2,67	0,98	0,02	probably_damaging	1	neutral	0,09	neutral	2,17	neutral	2,45	neutral	-1,15	low_impact	1,76	neutral	0,97	neutral	0,84	deleterious	2,27	18	0,70671114	0,85	neutral	0,26	neutral	0,13	neutral	0,35	neutral	0,1	8	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	-0,28	medium_impact	0,41	0,66	0,85	NA	NA	P	0,62	P	0,1	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10086	10086	A	G	MI.15020	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	28	10	N	D	Aac/Gac	-10,98	0	0	possibly_damaging	0,9	deleterious	0,02	neutral	1,97	neutral	-0,42	deleterious	-3,52	medium_impact	2,34	neutral	0,96	neutral	0,57	deleterious	2,47	19,3	0,44	0,55	neutral	0,23	disease	0,68	disease	0,57	disease	0,69	4	deleterious	0,99	neutral	0,06	deleterious	4	deleterious	0,59	low_impact	-1,58	medium_impact	-0,75	medium_impact	1,04	0,28	0,8	1,74	7,74	P	0,56	P	0,94	polymorphism	1	0,1	rs28358274	.	.	.	.	.	.	CPD	0,15	A10086G	Hypertensive end-stage renal disease	+	-	Reported	3
chrM	10086	10086	A	C	MI.15021	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	28	10	N	H	Aac/Cac	-10,98	0	0	probably_damaging	0,98	neutral	0,07	neutral	1,96	neutral	-0,86	deleterious	-3,9	medium_impact	3,04	neutral	0,83	neutral	0,34	deleterious	2,84	21,6	0,34	0,5	neutral	0,38	disease	0,69	disease	0,58	disease	0,73	5	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,65	low_impact	-2,24	medium_impact	-0,43	medium_impact	1,68	0,26	0,8	1,74	7,74	N	0,38	N	0,98	polymorphism	1	0,1	rs28358274	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10087	10087	A	C	MI.15022	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	29	10	N	T	aAc/aCc	1,05	0,07	0	probably_damaging	0,94	neutral	0,23	neutral	2,04	neutral	0,75	deleterious	-4,13	low_impact	0,88	neutral	0,77	neutral	0,68	neutral	1,31	12,34	0,29	0,45	neutral	0,19	neutral	0,28	neutral	0,23	neutral	0,45	1	neutral	0,95	neutral	0,15	neutral	-2	deleterious	0,6	low_impact	-1,8	medium_impact	-0,1	medium_impact	-0,3	0,3	0,8	1,74	7,74	N	0,4	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10087	10087	A	G	MI.15023	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	29	10	N	S	aAc/aGc	1,05	0,07	0	possibly_damaging	0,9	neutral	0,37	neutral	2,1	neutral	1,01	deleterious	-3,38	low_impact	0,86	neutral	0,78	neutral	0,64	neutral	1,37	12,66	0,42	0,55	neutral	0,16	neutral	0,22	neutral	0,29	neutral	0,35	3	neutral	0,9	neutral	0,24	neutral	-3	deleterious	0,58	low_impact	-1,58	medium_impact	0,06	medium_impact	-0,32	0,27	0,8	1,74	7,74	N	0,37	N	0,81	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10087	10087	A	T	MI.15024	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	29	10	N	I	aAc/aTc	1,05	0,07	0	probably_damaging	0,98	neutral	1	neutral	2,02	neutral	0,95	deleterious	-6,66	low_impact	1,14	neutral	0,82	neutral	0,54	deleterious	3,73	23,3	0,16	0,45	neutral	0,34	disease	0,84	neutral	0,3	disease	0,6	2	deleterious	0,98	deleterious	0,51	neutral	-2	deleterious	0,67	low_impact	-2,24	high_impact	1,85	medium_impact	-0,06	0,24	0,8	1,74	7,74	N	0,22	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10088	10088	C	A	MI.15025	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	30	10	N	K	aaC/aaA	2,67	0,15	0	probably_damaging	0,94	deleterious	0,03	neutral	2,01	neutral	0,52	deleterious	-4,5	medium_impact	3,04	neutral	0,83	neutral	0,31	deleterious	4,09	23,7	0,37	0,5	neutral	0,17	disease	0,82	disease	0,58	disease	0,78	6	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,63	low_impact	-1,8	medium_impact	-0,65	medium_impact	1,68	0,41	0,8	1,74	7,74	N	0,42	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10088	10088	C	G	MI.15026	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	30	10	N	K	aaC/aaG	2,67	0,15	0	probably_damaging	0,94	deleterious	0,03	neutral	2,01	neutral	0,52	deleterious	-4,5	medium_impact	3,04	neutral	0,83	neutral	0,31	deleterious	3,64	23,2	0,37	0,5	neutral	0,17	disease	0,82	disease	0,58	disease	0,78	6	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,63	low_impact	-1,8	medium_impact	-0,65	medium_impact	1,68	0,41	0,8	1,74	7,74	N	0,42	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10089	10089	A	T	MI.15027	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	31	11	T	S	Acc/Tcc	-9,36	0	0	possibly_damaging	0,9	neutral	0,46	neutral	1,95	neutral	-0,62	neutral	-1,38	low_impact	0,95	neutral	0,75	neutral	0,96	neutral	1,14	11,45	0,4	0,5	neutral	0,28	neutral	0,25	neutral	0,29	neutral	0,45	1	neutral	0,89	neutral	0,28	neutral	-3	deleterious	0,6	low_impact	-1,58	medium_impact	0,15	medium_impact	-0,24	0,38	0,8	10,43	8,48	N	0,41	N	0,1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10089	10089	A	G	MI.15028	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	31	11	T	A	Acc/Gcc	-9,36	0	0	possibly_damaging	0,9	neutral	0,41	neutral	1,98	neutral	0,11	neutral	-1,63	low_impact	1,67	neutral	0,75	neutral	0,88	neutral	1,49	13,27	0,25	0,45	neutral	0,2	neutral	0,29	neutral	0,3	neutral	0,44	1	neutral	0,9	neutral	0,26	neutral	-3	deleterious	0,59	low_impact	-1,58	medium_impact	0,1	medium_impact	0,42	0,23	0,8	10,43	8,48	N	0,4	N	0,2	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10089	10089	A	C	MI.15029	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	31	11	T	P	Acc/Ccc	-9,36	0	0	probably_damaging	0,96	neutral	0,07	neutral	1,88	neutral	-2,04	deleterious	-3,14	low_impact	1,59	neutral	0,67	damaging	0,08	deleterious	2,06	16,61	0,07	0,35	neutral	0,5	disease	0,86	disease	0,6	disease	0,78	6	deleterious	0,99	neutral	0,06	neutral	-2	deleterious	0,74	low_impact	-1,96	medium_impact	-0,43	medium_impact	0,35	0,28	0,8	10,43	8,48	N	0,24	N	0,8	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8393	8393	C	T	MI.1503	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	28	10	P	S	Ccc/Tcc	2,67	0,98	0,02	probably_damaging	1	deleterious	0,04	neutral	2,01	neutral	0,2	neutral	-1,26	low_impact	1,17	neutral	1	neutral	0,89	deleterious	2,5	19,46	0,62290357	0,85	neutral	0,18	neutral	0,09	neutral	0,32	neutral	0,04	9	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,67	low_impact	-3,6	medium_impact	-0,49	medium_impact	-0,1	0,28	0,85	NA	NA	P	0,67	P	0,44	polymorphism	0,98	0,04	rs121434446	other	Brain_pseudoatrophy,_reversible,_valproate-induced,_susceptibility_to	RCV000010270.4	MedGen	.	.	.	.	C8393T	Reversible brain pseudoatrophy	-	+	Reported	2
chrM	10090	10090	C	T	MI.15030	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	32	11	T	I	aCc/aTc	-2,88	0	0	probably_damaging	0,96	neutral	1	neutral	2	neutral	0,01	neutral	-1	neutral_impact	0,1	neutral	0,72	neutral	0,98	neutral	1,72	14,51	0,15	0,45	neutral	0,11	disease	0,52	neutral	0,29	neutral	0,43	1	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,62	low_impact	-1,96	high_impact	1,85	low_impact	-1,02	0,41	0,8	10,43	8,48	N	0,3	N	0,15	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10090	10090	C	A	MI.15031	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	32	11	T	N	aCc/aAc	-2,88	0	0	probably_damaging	0,96	neutral	0,09	neutral	1,88	neutral	-1,91	deleterious	-2,54	medium_impact	2,74	neutral	0,75	damaging	0,13	deleterious	2,33	18,34	0,28	0,45	neutral	0,43	disease	0,62	neutral	0,46	disease	0,5	0	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,66	low_impact	-1,96	medium_impact	-0,37	medium_impact	1,4	0,4	0,8	10,43	8,48	N	0,34	N	0,51	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10090	10090	C	G	MI.15032	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	32	11	T	S	aCc/aGc	-2,88	0	0	possibly_damaging	0,9	neutral	0,46	neutral	1,95	neutral	-0,62	neutral	-1,38	low_impact	0,95	neutral	0,75	neutral	0,96	neutral	1,54	13,51	0,4	0,5	neutral	0,28	neutral	0,25	neutral	0,29	neutral	0,45	1	neutral	0,89	neutral	0,28	neutral	-3	deleterious	0,6	low_impact	-1,58	medium_impact	0,15	medium_impact	-0,24	0,38	0,8	10,43	8,48	N	0,39	N	0,1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10092	10092	C	G	MI.15033	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	34	12	L	V	Ctc/Gtc	-15,6	0	0	probably_damaging	0,97	neutral	0,43	neutral	1,88	neutral	-0,43	neutral	-0,39	neutral_impact	0	neutral	0,81	neutral	0,97	neutral	1,46	13,08	0,3	0,45	neutral	0,24	neutral	0,29	neutral	0,32	neutral	0,43	1	neutral	0,97	neutral	0,23	neutral	-2	deleterious	0,67	low_impact	-2,08	medium_impact	0,12	low_impact	-1,11	0,31	0,8	3,48	7,77	N	0,33	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10092	10092	C	T	MI.15034	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	34	12	L	F	Ctc/Ttc	-15,6	0	0	probably_damaging	0,99	neutral	0,43	neutral	1,77	neutral	-1,95	neutral	-1,55	neutral_impact	0	neutral	0,8	neutral	0,89	deleterious	2,59	20,2	0,29	0,45	neutral	0,45	neutral	0,45	neutral	0,39	neutral	0,49	0	deleterious	0,99	neutral	0,22	neutral	-2	deleterious	0,73	low_impact	-2,52	medium_impact	0,12	low_impact	-1,11	0,38	0,8	3,48	7,77	N	0,3	N	0,36	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10092	10092	C	A	MI.15035	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	34	12	L	I	Ctc/Atc	-15,6	0	0	probably_damaging	0,97	neutral	0,88	neutral	1,89	neutral	-0,52	neutral	-0,3	neutral_impact	0	neutral	0,8	neutral	0,99	neutral	1,73	14,57	0,27	0,45	neutral	0,26	neutral	0,22	neutral	0,22	neutral	0,41	2	neutral	0,97	neutral	0,46	neutral	-2	deleterious	0,67	low_impact	-2,08	medium_impact	0,67	low_impact	-1,11	0,43	0,8	3,48	7,77	N	0,31	N	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10093	10093	T	G	MI.15036	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	35	12	L	R	cTc/cGc	-6,81	0	0	probably_damaging	1	neutral	0,07	neutral	1,72	neutral	-2,87	neutral	-2,15	neutral_impact	0	neutral	0,71	neutral	0,4	deleterious	3,96	23,6	0,04	0,35	neutral	0,49	disease	0,83	disease	0,71	disease	0,79	6	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,81	low_impact	-3,43	medium_impact	-0,43	low_impact	-1,11	0,22	0,8	3,48	7,77	N	0,28	N	0,76	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10093	10093	T	C	MI.15037	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	35	12	L	P	cTc/cCc	-6,81	0	0	probably_damaging	1	neutral	0,09	neutral	1,71	deleterious	-3,63	neutral	-2,44	neutral_impact	0	neutral	0,64	neutral	0,3	deleterious	3,67	23,3	0,05	0,35	disease	0,6	disease	0,82	disease	0,7	disease	0,78	6	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,82	low_impact	-3,43	medium_impact	-0,37	low_impact	-1,11	0,17	0,8	3,48	7,77	N	0,24	N	0,94	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10093	10093	T	A	MI.15038	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	35	12	L	H	cTc/cAc	-6,81	0	0	probably_damaging	1	neutral	0,11	neutral	1,71	deleterious	-3,56	deleterious	-2,65	neutral_impact	0	neutral	0,77	neutral	0,49	deleterious	3,88	23,5	0,07	0,35	disease	0,63	disease	0,62	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,76	low_impact	-3,43	medium_impact	-0,31	low_impact	-1,11	0,23	0,8	3,48	7,77	N	0,27	N	0,79	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10095	10095	C	A	MI.15039	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	37	13	L	M	Cta/Ata	-10,28	0	0	probably_damaging	1	neutral	0,17	neutral	0,81	neutral	-1,45	neutral	-1,74	medium_impact	2,27	neutral	0,81	neutral	0,59	deleterious	3,51	23,1	0,26	0,45	neutral	0,46	neutral	0,48	disease	0,53	neutral	0,46	1	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,71	low_impact	-3,43	medium_impact	-0,19	medium_impact	0,97	0,38	0,8	1,74	7,66	N	0,39	N	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8394	8394	C	G	MI.1504	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	29	10	P	R	cCc/cGc	-0,1	0,03	0	probably_damaging	1	deleterious	0,01	neutral	1,98	neutral	-1,24	neutral	-2,17	medium_impact	2,46	neutral	1	neutral	0,45	deleterious	2,26	17,89	0,51005936	0,85	neutral	0,36	neutral	0,27	disease	0,63	neutral	0,13	7	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,73	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,01	0,66	0,85	NA	NA	N	0,55	P	0,58	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10095	10095	C	G	MI.15040	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	37	13	L	V	Cta/Gta	-10,28	0	0	probably_damaging	0,97	neutral	0,44	neutral	0,92	neutral	-0,44	deleterious	-2,59	low_impact	1,58	neutral	0,83	neutral	0,59	deleterious	3,11	22,5	0,25	0,45	neutral	0,32	neutral	0,46	neutral	0,39	neutral	0,44	1	neutral	0,97	neutral	0,24	neutral	-2	deleterious	0,7	low_impact	-2,08	medium_impact	0,13	medium_impact	0,34	0,33	0,8	1,74	7,66	N	0,32	N	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10096	10096	T	C	MI.15041	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	38	13	L	P	cTa/cCa	-2,42	0	0	probably_damaging	1	deleterious	0,02	neutral	0,71	deleterious	-4,43	deleterious	-6,25	medium_impact	2,96	damaging	0,6	damaging	0,17	deleterious	3,69	23,3	0,06	0,35	disease	0,85	disease	0,82	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,85	low_impact	-3,43	medium_impact	-0,75	medium_impact	1,61	0,26	0,8	1,74	7,66	N	0,25	N	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10096	10096	T	G	MI.15042	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	38	13	L	R	cTa/cGa	-2,42	0	0	probably_damaging	1	deleterious	0,01	neutral	0,72	deleterious	-3,87	deleterious	-5,37	medium_impact	2,96	neutral	0,63	damaging	0,2	deleterious	3,96	23,6	0,06	0,35	disease	0,82	disease	0,88	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,88	low_impact	-3,43	medium_impact	-0,92	medium_impact	1,61	0,18	0,8	1,74	7,66	N	0,25	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10096	10096	T	A	MI.15043	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	38	13	L	Q	cTa/cAa	-2,42	0	0	probably_damaging	1	deleterious	0,01	neutral	0,71	deleterious	-4,02	deleterious	-5,36	medium_impact	2,96	neutral	0,73	damaging	0,24	deleterious	3,86	23,5	0,08	0,35	disease	0,81	disease	0,73	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-3,43	medium_impact	-0,92	medium_impact	1,61	0,22	0,8	1,74	7,66	N	0,25	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10098	10098	G	A	MI.15044	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	40	14	A	T	Gcc/Acc	-4,96	0	0	probably_damaging	0,99	neutral	0,11	neutral	0,95	neutral	-0,59	neutral	-0,91	low_impact	0,92	neutral	0,9	neutral	0,97	deleterious	2,75	21,1	0,23	0,45	neutral	0,2	neutral	0,37	neutral	0,33	neutral	0,43	1	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,66	low_impact	-2,52	medium_impact	-0,31	medium_impact	-0,27	0,63	0,8	11,3	8,63	N	0,5	N	0,06	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10098	10098	G	C	MI.15045	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	40	14	A	P	Gcc/Ccc	-4,96	0	0	probably_damaging	1	deleterious	0	neutral	0,92	neutral	-1,39	deleterious	-2,97	low_impact	1,66	neutral	0,77	neutral	0,8	deleterious	3,54	23,1	0,09	0,35	disease	0,55	disease	0,88	disease	0,52	disease	0,6	2	deleterious	1	neutral	0	deleterious	2	deleterious	0,82	low_impact	-3,43	low_impact	-1,47	medium_impact	0,41	0,43	0,8	11,3	8,63	N	0,34	N	0,79	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10098	10098	G	T	MI.15046	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	40	14	A	S	Gcc/Tcc	-4,96	0	0	probably_damaging	0,99	neutral	0,21	neutral	1,01	neutral	0,09	neutral	-0,31	neutral_impact	-0,11	neutral	0,73	neutral	0,93	deleterious	0,76	9,21	0,25	0,45	neutral	0,09	neutral	0,06	neutral	0,25	neutral	0,23	5	deleterious	0,99	neutral	0,11	neutral	-2	deleterious	0,62	low_impact	-2,52	medium_impact	-0,13	low_impact	-1,21	0,4	0,8	11,3	8,63	N	0,47	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10099	10099	C	T	MI.15047	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	41	14	A	V	gCc/gTc	0,13	0	0	probably_damaging	0,99	neutral	0,3	neutral	1,01	neutral	0,09	neutral	-2,48	low_impact	1,19	neutral	0,79	neutral	0,76	deleterious	3,16	22,6	0,17	0,45	neutral	0,44	disease	0,68	neutral	0,38	disease	0,54	1	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,74	low_impact	-2,52	medium_impact	-0,01	medium_impact	-0,02	0,48	0,8	11,3	8,63	N	0,32	N	0,48	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10099	10099	C	A	MI.15048	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	41	14	A	D	gCc/gAc	0,13	0	0	probably_damaging	1	deleterious	0	neutral	0,88	neutral	-2,83	deleterious	-3,12	medium_impact	2,47	neutral	0,72	neutral	0,32	deleterious	4,44	24,2	0,05	0,35	disease	0,56	disease	0,86	disease	0,7	disease	0,8	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,8	low_impact	-3,43	low_impact	-1,47	medium_impact	1,16	0,3	0,8	11,3	8,63	N	0,3	N	0,89	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10099	10099	C	G	MI.15049	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	41	14	A	G	gCc/gGc	0,13	0	0	probably_damaging	0,99	deleterious	0,03	neutral	0,94	neutral	-0,94	neutral	-2,43	low_impact	1,57	neutral	0,75	neutral	0,51	deleterious	3,75	23,3	0,25	0,45	neutral	0,38	disease	0,63	disease	0,57	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,7	low_impact	-2,52	medium_impact	-0,65	medium_impact	0,33	0,5	0,8	11,3	8,63	N	0,36	N	0,42	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8394	8394	C	A	MI.1505	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	29	10	P	H	cCc/cAc	-0,1	0,03	0	probably_damaging	1	deleterious	0,02	neutral	1,97	neutral	-1,79	neutral	-1,42	medium_impact	2,46	neutral	0,95	neutral	0,44	deleterious	3,66	23,2	0,47886177	0,85	neutral	0,46	neutral	0,23	disease	0,63	neutral	0,14	7	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,73	low_impact	-3,6	medium_impact	-0,66	medium_impact	1,01	0,7	0,85	NA	NA	N	0,49	N	0,42	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10101	10101	T	A	MI.15050	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	43	15	L	M	Tta/Ata	-6,12	0	0,03	probably_damaging	1	neutral	0,23	neutral	0,76	neutral	-2,02	neutral	-0,05	neutral_impact	0,68	neutral	0,82	neutral	0,98	deleterious	2,05	16,55	0,24	0,45	neutral	0,33	neutral	0,17	neutral	0,29	neutral	0,31	4	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,66	low_impact	-3,43	medium_impact	-0,1	medium_impact	-0,49	0,38	0,8	4,35	8,63	N	0,46	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10101	10101	T	G	MI.15051	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	43	15	L	V	Tta/Gta	-6,12	0	0,03	probably_damaging	0,97	neutral	0,51	neutral	0,87	neutral	-0,8	neutral	-0,7	neutral_impact	0,66	neutral	0,78	neutral	0,91	neutral	1,78	14,87	0,25	0,45	neutral	0,18	neutral	0,22	neutral	0,28	neutral	0,39	2	neutral	0,97	neutral	0,27	neutral	-2	deleterious	0,65	low_impact	-2,08	medium_impact	0,2	medium_impact	-0,5	0,43	0,8	4,35	8,63	N	0,32	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10102	10102	T	G	MI.15052	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	44	15	L	W	tTa/tGa	-3,34	0	0	probably_damaging	1	neutral	0,18	neutral	0,69	deleterious	-4,9	deleterious	-2,64	medium_impact	2,56	neutral	0,77	neutral	0,35	deleterious	3,56	23,1	0,08	0,35	disease	0,65	disease	0,66	neutral	0,49	neutral	0,5	0	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,75	low_impact	-3,43	medium_impact	-0,18	medium_impact	1,24	0,19	0,8	4,35	8,63	N	0,31	N	0,6	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10102	10102	T	C	MI.15053	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	44	15	L	S	tTa/tCa	-3,34	0	0	probably_damaging	0,99	neutral	0,44	neutral	0,75	neutral	-2,27	neutral	-0,31	neutral_impact	0,3	neutral	0,89	neutral	1	neutral	1,76	14,76	0,09	0,35	neutral	0,13	neutral	0,23	neutral	0,36	neutral	0,4	2	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,65	low_impact	-2,52	medium_impact	0,13	medium_impact	-0,83	0,19	0,8	4,35	8,63	N	0,37	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10103	10103	A	T	MI.15054	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	45	15	L	F	ttA/ttT	-0,8	0	0	probably_damaging	0,99	neutral	0,71	neutral	0,78	neutral	-1,8	neutral	-1,38	low_impact	1,4	neutral	0,77	neutral	0,88	deleterious	2,15	17,21	0,27	0,45	neutral	0,25	neutral	0,39	neutral	0,31	neutral	0,45	1	deleterious	0,99	neutral	0,36	neutral	-2	deleterious	0,68	low_impact	-2,52	medium_impact	0,41	medium_impact	0,18	0,44	0,8	4,35	8,63	N	0,26	N	0,15	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10103	10103	A	C	MI.15055	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	45	15	L	F	ttA/ttC	-0,8	0	0	probably_damaging	0,99	neutral	0,71	neutral	0,78	neutral	-1,8	neutral	-1,38	low_impact	1,4	neutral	0,77	neutral	0,88	deleterious	2,03	16,38	0,27	0,45	neutral	0,25	neutral	0,39	neutral	0,31	neutral	0,45	1	deleterious	0,99	neutral	0,36	neutral	-2	deleterious	0,68	low_impact	-2,52	medium_impact	0,41	medium_impact	0,18	0,44	0,8	4,35	8,63	N	0,24	N	0,15	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10104	10104	C	A	MI.15056	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	46	16	L	M	Cta/Ata	-11,21	0	0,02	probably_damaging	1	neutral	0,2	neutral	0,78	neutral	-2,02	neutral	-1,14	medium_impact	2,04	neutral	0,86	neutral	0,83	deleterious	2,43	19	0,25	0,45	neutral	0,34	neutral	0,33	neutral	0,4	neutral	0,46	1	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,67	low_impact	-3,43	medium_impact	-0,14	medium_impact	0,76	0,52	0,8	10,43	8,69	N	0,45	N	0,51	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10104	10104	C	G	MI.15057	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	46	16	L	V	Cta/Gta	-11,21	0	0,02	probably_damaging	0,97	neutral	0,41	neutral	0,92	neutral	-0,51	neutral	-0,85	low_impact	1,22	neutral	0,78	neutral	0,99	neutral	1,41	12,84	0,22	0,45	neutral	0,15	neutral	0,17	neutral	0,34	neutral	0,3	4	neutral	0,97	neutral	0,22	neutral	-2	deleterious	0,64	low_impact	-2,08	medium_impact	0,1	medium_impact	0,01	0,48	0,8	10,43	8,69	N	0,35	N	0,38	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10105	10105	T	G	MI.15058	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	47	16	L	R	cTa/cGa	-7,51	0	0	probably_damaging	1	neutral	0,16	neutral	0,73	deleterious	-3,52	deleterious	-4,77	medium_impact	3,14	neutral	0,7	neutral	0,35	deleterious	3,96	23,6	0,05	0,35	disease	0,55	disease	0,86	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,83	low_impact	-3,43	medium_impact	-0,21	medium_impact	1,77	0,24	0,8	10,43	8,69	N	0,32	N	0,94	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10105	10105	T	C	MI.15059	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	47	16	L	P	cTa/cCa	-7,51	0	0	probably_damaging	1	neutral	0,2	neutral	0,72	deleterious	-4,14	deleterious	-5,19	medium_impact	3,14	damaging	0,6	damaging	0,24	deleterious	3,75	23,3	0,05	0,35	disease	0,64	disease	0,84	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,83	low_impact	-3,43	medium_impact	-0,14	medium_impact	1,77	0,33	0,8	10,43	8,69	N	0,28	N	0,94	polymorphism	1	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8394	8394	C	T	MI.1506	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	29	10	P	L	cCc/cTc	-0,1	0,03	0	probably_damaging	1	neutral	1	neutral	2,23	neutral	2,81	neutral	0,02	neutral_impact	0,21	neutral	1	neutral	0,94	neutral	1,44	13	0,56962521	0,85	neutral	0,16	neutral	0,16	neutral	0,35	neutral	0,08	8	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,69	low_impact	-3,6	high_impact	1,98	medium_impact	-0,92	0,76	0,85	NA	NA	N	0,33	N	0,22	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10105	10105	T	A	MI.15060	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	47	16	L	Q	cTa/cAa	-7,51	0	0	probably_damaging	1	neutral	0,09	neutral	0,72	deleterious	-3,67	deleterious	-4,65	medium_impact	3,14	neutral	0,8	neutral	0,42	deleterious	4,03	23,6	0,08	0,35	disease	0,56	disease	0,6	disease	0,62	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,74	low_impact	-3,43	medium_impact	-0,37	medium_impact	1,77	0,23	0,8	10,43	8,69	N	0,35	N	0,89	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10107	10107	C	A	MI.15061	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	49	17	L	M	Cta/Ata	-7,51	0	0	probably_damaging	1	neutral	0,24	neutral	0,81	neutral	-1,74	neutral	-1,65	medium_impact	2,21	neutral	0,72	neutral	0,53	deleterious	3,52	23,1	0,23	0,45	neutral	0,49	neutral	0,4	neutral	0,37	neutral	0,38	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,71	low_impact	-3,43	medium_impact	-0,09	medium_impact	0,92	0,4	0,8	4,35	9	N	0,4	N	0,66	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10107	10107	C	G	MI.15062	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	49	17	L	V	Cta/Gta	-7,51	0	0	probably_damaging	0,97	neutral	0,57	neutral	0,87	neutral	-0,91	deleterious	-2,54	medium_impact	2,33	neutral	0,71	neutral	0,61	deleterious	3,2	22,7	0,24	0,45	neutral	0,26	neutral	0,45	disease	0,55	neutral	0,42	2	neutral	0,97	neutral	0,3	deleterious	1	deleterious	0,69	low_impact	-2,08	medium_impact	0,26	medium_impact	1,03	0,43	0,8	4,35	9	N	0,31	N	0,19	polymorphism	1	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10108	10108	T	G	MI.15063	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	50	17	L	R	cTa/cGa	-0,8	0	0	probably_damaging	1	neutral	0,1	neutral	0,74	deleterious	-3,4	deleterious	-5,6	high_impact	3,98	damaging	0,55	damaging	0,04	deleterious	3,98	23,6	0,06	0,35	disease	0,8	disease	0,86	disease	0,75	disease	0,82	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,88	low_impact	-3,43	medium_impact	-0,34	high_impact	2,54	0,18	0,8	4,35	9	N	0,36	N	0,98	polymorphism	1	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10108	10108	T	A	MI.15064	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	50	17	L	Q	cTa/cAa	-0,8	0	0	probably_damaging	1	deleterious	0,04	neutral	0,74	deleterious	-3,26	deleterious	-5,53	high_impact	3,63	damaging	0,59	damaging	0,06	deleterious	3,99	23,6	0,09	0,35	disease	0,81	disease	0,72	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,79	low_impact	-3,43	medium_impact	-0,58	high_impact	2,22	0,21	0,8	4,35	9	N	0,27	N	0,93	polymorphism	1	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10108	10108	T	C	MI.15065	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	50	17	L	P	cTa/cCa	-0,8	0	0	probably_damaging	1	deleterious	0,03	neutral	0,74	deleterious	-3,47	deleterious	-6,48	medium_impact	3,08	damaging	0,53	damaging	0,05	deleterious	3,76	23,3	0,06	0,35	disease	0,85	disease	0,77	disease	0,74	disease	0,8	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,85	low_impact	-3,43	medium_impact	-0,65	medium_impact	1,72	0,28	0,8	4,35	9	N	0,27	N	0,93	polymorphism	1	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10110	10110	A	C	MI.15066	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	52	18	M	L	Ata/Cta	-2,42	0	0	possibly_damaging	0,66	neutral	1	neutral	1,15	neutral	1,38	neutral	-0,25	neutral_impact	-0,04	neutral	0,77	neutral	0,79	deleterious	1,91	15,62	0,15	0,45	neutral	0,14	disease	0,55	neutral	0,37	neutral	0,43	1	neutral	0,66	deleterious	0,67	neutral	-3	neutral	0,4	medium_impact	-0,98	high_impact	1,85	low_impact	-1,15	0,24	0,8	16,52	10,1	N	0,27	N	0,4	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10110	10110	A	G	MI.15067	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	52	18	M	V	Ata/Gta	-2,42	0	0	possibly_damaging	0,75	neutral	0,25	neutral	1,08	neutral	0,86	neutral	0,89	neutral_impact	0,66	neutral	0,83	neutral	0,99	deleterious	0,04	2,96	0,23	0,45	neutral	0,09	neutral	0,32	neutral	0,35	neutral	0,42	2	neutral	0,83	neutral	0,25	neutral	-3	deleterious	0,44	low_impact	-1,15	medium_impact	-0,08	medium_impact	-0,5	0,21	0,8	16,52	10,1	N	0,34	N	0,07	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10110	10110	A	T	MI.15068	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	52	18	M	L	Ata/Tta	-2,42	0	0	possibly_damaging	0,66	neutral	1	neutral	1,15	neutral	1,38	neutral	-0,25	neutral_impact	-0,04	neutral	0,77	neutral	0,79	deleterious	2,01	16,27	0,15	0,45	neutral	0,14	disease	0,55	neutral	0,37	neutral	0,43	1	neutral	0,66	deleterious	0,67	neutral	-3	neutral	0,4	medium_impact	-0,98	high_impact	1,85	low_impact	-1,15	0,24	0,8	16,52	10,1	N	0,3	N	0,4	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10111	10111	T	C	MI.15069	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	53	18	M	T	aTa/aCa	0,36	0	0	possibly_damaging	0,88	neutral	0,06	neutral	0,96	neutral	-0,53	neutral	-2,23	low_impact	1,05	neutral	0,86	neutral	0,86	neutral	1,63	13,99	0,12	0,4	neutral	0,21	neutral	0,23	neutral	0,41	neutral	0,41	2	neutral	0,97	neutral	0,09	neutral	-3	deleterious	0,6	low_impact	-1,5	medium_impact	-0,47	medium_impact	-0,15	0,15	0,8	16,52	10,1	N	0,44	N	0,37	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8396	8396	A	C	MI.1507	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	31	11	T	P	Acc/Ccc	-4,73	0	0	probably_damaging	0,99	neutral	0,22	neutral	1,78	deleterious	-4,4	deleterious	-3,41	low_impact	1,57	neutral	0,99	neutral	0,34	deleterious	2,66	20,5	0,26709301	0,85	disease	0,66	neutral	0,49	disease	0,7	disease	0,52	0	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,77	low_impact	-2,65	medium_impact	-0,02	medium_impact	0,25	0,62	0,85	4,41	7,72	N	0,49	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10111	10111	T	A	MI.15070	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	53	18	M	K	aTa/aAa	0,36	0	0	possibly_damaging	0,88	deleterious	0,02	neutral	0,92	neutral	-1,89	deleterious	-3,69	medium_impact	2,99	neutral	0,76	neutral	0,48	deleterious	3,89	23,5	0,06	0,35	neutral	0,42	disease	0,77	disease	0,68	disease	0,78	6	deleterious	0,99	neutral	0,07	deleterious	4	deleterious	0,7	low_impact	-1,5	medium_impact	-0,75	medium_impact	1,63	0,19	0,8	16,52	10,1	N	0,41	N	0,86	disease_causing	1	0,61	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10112	10112	A	C	MI.15071	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	54	18	M	I	atA/atC	1,05	0	0	possibly_damaging	0,82	neutral	0,49	neutral	1,13	neutral	1,24	neutral	0,9	neutral_impact	-0,14	neutral	0,77	neutral	1	deleterious	0,42	6,76	0,19	0,45	neutral	0,09	neutral	0,26	neutral	0,3	neutral	0,41	2	neutral	0,8	neutral	0,34	neutral	-3	deleterious	0,52	low_impact	-1,31	medium_impact	0,18	low_impact	-1,24	0,2	0,8	16,52	10,1	N	0,36	N	0,1	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10112	10112	A	T	MI.15072	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	54	18	M	I	atA/atT	1,05	0	0	possibly_damaging	0,82	neutral	0,49	neutral	1,13	neutral	1,24	neutral	0,9	neutral_impact	-0,14	neutral	0,77	neutral	1	deleterious	0,47	7,23	0,19	0,45	neutral	0,09	neutral	0,26	neutral	0,3	neutral	0,41	2	neutral	0,8	neutral	0,34	neutral	-3	deleterious	0,52	low_impact	-1,31	medium_impact	0,18	low_impact	-1,24	0,2	0,8	16,52	10,1	N	0,36	N	0,1	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10113	10113	A	G	MI.15073	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	55	19	I	V	Att/Gtt	-5,19	0	0	benign	0,04	neutral	0,35	neutral	0,96	neutral	-0,33	neutral	-0,02	neutral_impact	0,8	neutral	0,79	neutral	0,96	neutral	-0,42	0,35	0,47	0,55	neutral	0,15	neutral	0,14	neutral	0,36	neutral	0,32	4	neutral	0,63	deleterious	0,66	neutral	-6	neutral	0,12	medium_impact	0,53	medium_impact	0,04	medium_impact	-0,38	0,3	0,8	3,48	8,85	N	0,39	N	0,49	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10113	10113	A	T	MI.15074	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	55	19	I	F	Att/Ttt	-5,19	0	0	benign	0,4	neutral	0,56	neutral	0,88	neutral	-1,15	neutral	-1,74	neutral_impact	0,78	neutral	0,76	neutral	0,93	deleterious	0,73	8,99	0,2	0,45	neutral	0,14	neutral	0,45	neutral	0,35	neutral	0,43	1	neutral	0,39	deleterious	0,58	neutral	-6	neutral	0,36	medium_impact	-0,56	medium_impact	0,25	medium_impact	-0,39	0,44	0,8	3,48	8,85	N	0,31	N	0,42	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10113	10113	A	C	MI.15075	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	55	19	I	L	Att/Ctt	-5,19	0	0	benign	0,04	neutral	0,89	neutral	1,01	neutral	0,07	neutral	-0,06	neutral_impact	-0,98	neutral	0,78	neutral	0,98	neutral	-0,97	0,02	0,24	0,45	neutral	0,09	neutral	0,19	neutral	0,26	neutral	0,35	3	neutral	0,04	deleterious	0,93	neutral	-6	neutral	0,11	medium_impact	0,53	medium_impact	0,69	low_impact	-2,01	0,48	0,8	3,48	8,85	N	0,3	N	0,18	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10114	10114	T	G	MI.15076	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	56	19	I	S	aTt/aGt	-8,2	0	0	benign	0,08	neutral	0,54	neutral	0,85	neutral	-1,66	neutral	-0,91	neutral_impact	0,56	neutral	0,82	neutral	0,97	deleterious	0,76	9,23	0,05	0,35	neutral	0,22	neutral	0,47	neutral	0,41	neutral	0,44	1	neutral	0,39	deleterious	0,73	neutral	-6	neutral	0,17	medium_impact	0,24	medium_impact	0,23	medium_impact	-0,6	0,19	0,8	3,48	8,85	N	0,31	N	0,25	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10114	10114	T	A	MI.15077	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	56	19	I	N	aTt/aAt	-8,2	0	0	benign	0,26	neutral	0,19	neutral	0,8	neutral	-2,92	neutral	-2,14	medium_impact	1,98	neutral	0,74	neutral	0,34	deleterious	2,6	20,2	0,12	0,4	neutral	0,45	disease	0,63	disease	0,52	disease	0,59	2	neutral	0,77	neutral	0,47	neutral	-3	deleterious	0,43	medium_impact	-0,31	medium_impact	-0,16	medium_impact	0,71	0,2	0,8	3,48	8,85	N	0,35	N	0,58	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10114	10114	T	C	MI.15078	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	56	19	I	T	aTt/aCt	-8,2	0	0	benign	0	neutral	0,54	neutral	0,87	neutral	-1,29	neutral	0,56	neutral_impact	-0,01	neutral	0,9	neutral	0,99	neutral	-1,02	0,01	0,22	0,45	neutral	0,17	neutral	0,14	neutral	0,31	neutral	0,24	5	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,1	medium_impact	1,99	medium_impact	0,23	low_impact	-1,12	0,24	0,8	3,48	8,85	N	0,32	N	0,06	polymorphism	1	0,18	rs879734442	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10115	10115	T	G	MI.15079	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	57	19	I	M	atT/atG	-1,72	0	0,01	possibly_damaging	0,6	neutral	0,69	neutral	0,85	neutral	-1,55	neutral	-0,3	neutral_impact	0,43	neutral	0,76	neutral	0,98	neutral	1,53	13,47	0,34	0,5	neutral	0,29	neutral	0,17	neutral	0,29	neutral	0,29	4	neutral	0,51	deleterious	0,55	neutral	-3	deleterious	0,48	medium_impact	-0,88	medium_impact	0,38	medium_impact	-0,71	0,54	0,8	3,48	8,85	N	0,31	N	0,54	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8396	8396	A	G	MI.1508	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	31	11	T	A	Acc/Gcc	-4,73	0	0	probably_damaging	0,97	neutral	0,64	neutral	1,86	neutral	-1,47	neutral	-1,88	low_impact	1,92	neutral	0,99	neutral	0,64	deleterious	2,11	16,93	0,6294906	0,85	neutral	0,32	neutral	0,11	disease	0,56	neutral	0,11	8	neutral	0,97	neutral	0,34	neutral	-2	deleterious	0,67	low_impact	-2,19	medium_impact	0,43	medium_impact	0,55	0,53	0,85	4,41	7,72	N	0,4	N	0,42	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10115	10115	T	A	MI.15080	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	57	19	I	M	atT/atA	-1,72	0	0,01	possibly_damaging	0,6	neutral	0,69	neutral	0,85	neutral	-1,55	neutral	-0,3	neutral_impact	0,43	neutral	0,76	neutral	0,98	deleterious	1,86	15,33	0,34	0,5	neutral	0,29	neutral	0,17	neutral	0,29	neutral	0,29	4	neutral	0,51	deleterious	0,55	neutral	-3	deleterious	0,48	medium_impact	-0,88	medium_impact	0,38	medium_impact	-0,71	0,54	0,8	3,48	8,85	N	0,31	N	0,54	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10116	10116	A	C	MI.15081	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	58	20	I	L	Att/Ctt	-6,35	0	0	benign	0	neutral	0,53	neutral	1,23	neutral	1,29	neutral	-1,68	low_impact	1,15	neutral	0,77	neutral	0,91	deleterious	0,48	7,25	0,22	0,45	neutral	0,15	neutral	0,28	neutral	0,31	neutral	0,44	1	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,11	medium_impact	1,99	medium_impact	0,22	medium_impact	-0,05	0,52	0,8	1,74	8,77	N	0,35	N	0,65	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10116	10116	A	T	MI.15082	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	58	20	I	F	Att/Ttt	-6,35	0	0	benign	0,18	neutral	0,68	neutral	0,88	neutral	-1,71	deleterious	-3,68	medium_impact	2,5	neutral	0,67	neutral	0,31	neutral	1,8	14,97	0,19	0,45	disease	0,51	disease	0,68	neutral	0,43	disease	0,52	0	neutral	0,2	deleterious	0,75	neutral	-3	neutral	0,32	medium_impact	-0,12	medium_impact	0,37	medium_impact	1,18	0,54	0,8	1,74	8,77	N	0,23	N	0,94	polymorphism	1	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10116	10116	A	G	MI.15083	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	58	20	I	V	Att/Gtt	-6,35	0	0	benign	0,03	neutral	0,45	neutral	1,04	neutral	0,29	neutral	-0,39	neutral_impact	0,26	neutral	0,84	neutral	0,99	neutral	-1,06	0,01	0,3	0,45	neutral	0,15	neutral	0,06	neutral	0,32	neutral	0,24	5	neutral	0,52	deleterious	0,71	neutral	-6	neutral	0,1	medium_impact	0,65	medium_impact	0,14	medium_impact	-0,87	0,35	0,8	1,74	8,77	N	0,42	N	0,28	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10117	10117	T	G	MI.15084	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	59	20	I	S	aTt/aGt	-0,33	0	0	benign	0,36	neutral	0,39	neutral	0,89	neutral	-1,57	deleterious	-5,15	medium_impact	2,75	neutral	0,68	neutral	0,35	deleterious	2,44	19,09	0,06	0,35	disease	0,66	disease	0,7	disease	0,52	disease	0,6	2	neutral	0,54	deleterious	0,52	neutral	-3	deleterious	0,46	medium_impact	-0,49	medium_impact	0,08	medium_impact	1,41	0,2	0,8	1,74	8,77	N	0,3	N	0,95	polymorphism	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10117	10117	T	C	MI.15085	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	59	20	I	T	aTt/aCt	-0,33	0	0	benign	0,19	neutral	0,46	neutral	0,9	neutral	-1,25	deleterious	-4,02	medium_impact	2,61	neutral	0,84	neutral	0,42	neutral	1,39	12,76	0,14	0,4	disease	0,53	neutral	0,49	neutral	0,43	disease	0,52	0	neutral	0,45	deleterious	0,64	neutral	-3	neutral	0,34	medium_impact	-0,15	medium_impact	0,15	medium_impact	1,28	0,29	0,8	1,74	8,77	N	0,33	N	0,94	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10117	10117	T	A	MI.15086	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	59	20	I	N	aTt/aAt	-0,33	0	0	possibly_damaging	0,65	neutral	0,06	neutral	0,85	neutral	-2,86	deleterious	-6,21	high_impact	3,65	neutral	0,79	neutral	0,41	deleterious	3,92	23,5	0,11	0,4	disease	0,79	disease	0,78	disease	0,61	disease	0,77	5	neutral	0,94	neutral	0,21	deleterious	1	deleterious	0,69	medium_impact	-0,96	medium_impact	-0,47	high_impact	2,24	0,19	0,8	1,74	8,77	N	0,37	N	0,99	polymorphism	1	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10118	10118	T	A	MI.15087	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	60	20	I	M	atT/atA	4,52	0,7	0	benign	0,25	neutral	0,6	neutral	0,91	neutral	-1,11	neutral	-2,38	low_impact	1,53	neutral	0,81	neutral	0,69	neutral	1,73	14,6	0,25	0,45	neutral	0,35	neutral	0,48	neutral	0,4	disease	0,51	0	neutral	0,29	deleterious	0,68	neutral	-6	neutral	0,39	medium_impact	-0,29	medium_impact	0,29	medium_impact	0,29	0,56	0,8	1,74	8,77	N	0,32	N	0,73	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10118	10118	T	G	MI.15088	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	60	20	I	M	atT/atG	4,52	0,7	0	benign	0,25	neutral	0,6	neutral	0,91	neutral	-1,11	neutral	-2,38	low_impact	1,53	neutral	0,81	neutral	0,69	neutral	1,44	13	0,25	0,45	neutral	0,35	neutral	0,48	neutral	0,4	disease	0,51	0	neutral	0,29	deleterious	0,68	neutral	-6	neutral	0,39	medium_impact	-0,29	medium_impact	0,29	medium_impact	0,29	0,56	0,8	1,74	8,77	N	0,31	N	0,73	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10119	10119	A	T	MI.15089	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	61	21	T	S	Aca/Tca	-6,12	0	0	benign	0,02	neutral	0,26	neutral	1,17	neutral	0,85	neutral	0,48	neutral_impact	-0,46	neutral	0,72	neutral	0,85	neutral	-1,06	0,01	0,36	0,5	neutral	0,09	neutral	0,08	neutral	0,3	neutral	0,2	6	neutral	0,73	deleterious	0,62	neutral	-6	neutral	0,11	medium_impact	0,81	medium_impact	-0,06	low_impact	-1,53	0,58	0,8	20	14,7	N	0,47	N	0,35	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8396	8396	A	T	MI.1509	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	31	11	T	S	Acc/Tcc	-4,73	0	0	probably_damaging	0,97	neutral	0,49	neutral	1,84	neutral	-1,87	neutral	-2,12	low_impact	1,36	neutral	1	neutral	0,63	deleterious	2,5	19,48	0,52918828	0,85	neutral	0,42	neutral	0,16	neutral	0,49	neutral	0,12	8	neutral	0,97	neutral	0,26	neutral	-2	deleterious	0,66	low_impact	-2,19	medium_impact	0,28	medium_impact	0,07	0,72	0,85	4,41	7,72	N	0,42	N	0,43	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10119	10119	A	G	MI.15090	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	61	21	T	A	Aca/Gca	-6,12	0	0	benign	0,15	neutral	0,37	neutral	1,07	neutral	0,64	neutral	2,24	neutral_impact	-1,74	neutral	0,79	neutral	0,95	neutral	-1,24	0,01	0,3	0,45	neutral	0,1	neutral	0,15	neutral	0,31	neutral	0,23	5	neutral	0,56	deleterious	0,61	neutral	-6	neutral	0,2	medium_impact	-0,04	medium_impact	0,06	low_impact	-2,7	0,35	0,8	20	14,7	N	0,26	N	0	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10119	10119	A	C	MI.15091	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	61	21	T	P	Aca/Cca	-6,12	0	0	possibly_damaging	0,49	neutral	0,05	neutral	0,95	neutral	-1,08	neutral	-1,74	neutral_impact	0,63	damaging	0,6	neutral	0,41	deleterious	3,04	22,4	0,08	0,35	neutral	0,42	disease	0,86	disease	0,69	disease	0,81	6	neutral	0,95	neutral	0,28	neutral	-3	deleterious	0,66	medium_impact	-0,7	medium_impact	-0,52	medium_impact	-0,53	0,35	0,8	20	14,7	N	0,32	N	0,68	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10120	10120	C	T	MI.15092	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	62	21	T	M	aCa/aTa	2,67	0,93	0	possibly_damaging	0,86	neutral	0,24	neutral	0,95	neutral	-1,76	neutral	-1,42	neutral_impact	0,43	neutral	0,86	neutral	0,68	deleterious	2,64	20,5	0,17	0,45	disease	0,51	disease	0,53	neutral	0,4	neutral	0,49	0	neutral	0,9	neutral	0,19	neutral	-3	deleterious	0,68	low_impact	-1,43	medium_impact	-0,09	medium_impact	-0,71	0,52	0,8	20	14,7	N	0,39	N	0,18	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10120	10120	C	A	MI.15093	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	62	21	T	K	aCa/aAa	2,67	0,93	0	benign	0,22	neutral	0,08	neutral	1	neutral	0,31	neutral	-1,59	low_impact	1,21	neutral	0,72	neutral	0,52	deleterious	2,54	19,72	0,14	0,4	neutral	0,27	disease	0,75	disease	0,62	disease	0,72	4	neutral	0,91	neutral	0,43	neutral	-6	neutral	0,37	medium_impact	-0,22	medium_impact	-0,4	medium_impact	0	0,42	0,8	20	14,7	N	0,42	N	0,59	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10122	10122	T	G	MI.15094	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	64	22	F	V	Ttt/Gtt	-1,95	0	0	possibly_damaging	0,82	neutral	0,5	neutral	0,97	neutral	-0,31	deleterious	-6,82	medium_impact	2,77	neutral	0,72	damaging	0,08	deleterious	3,91	23,5	0,18	0,45	neutral	0,32	disease	0,86	disease	0,64	disease	0,74	5	neutral	0,81	neutral	0,34	NA	0	deleterious	0,66	low_impact	-1,31	medium_impact	0,19	medium_impact	1,43	0,26	0,8	NA	NA	N	0,27	N	0,96	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10122	10122	T	A	MI.15095	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	64	22	F	I	Ttt/Att	-1,95	0	0	possibly_damaging	0,82	neutral	0,4	neutral	0,95	neutral	-0,52	deleterious	-5,82	medium_impact	2,35	neutral	0,78	damaging	0,11	deleterious	4,24	23,9	0,18	0,45	neutral	0,37	disease	0,84	neutral	0,47	disease	0,53	1	neutral	0,83	neutral	0,29	NA	0	deleterious	0,68	low_impact	-1,31	medium_impact	0,09	medium_impact	1,05	0,54	0,8	NA	NA	N	0,3	N	0,95	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10122	10122	T	C	MI.15096	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	64	22	F	L	Ttt/Ctt	-1,95	0	0	benign	0,12	neutral	0,65	neutral	1,03	neutral	0,21	deleterious	-5,79	medium_impact	1,94	neutral	0,81	damaging	0,18	deleterious	3,85	23,4	0,3	0,45	neutral	0,31	disease	0,78	neutral	0,46	disease	0,52	0	neutral	0,24	deleterious	0,77	neutral	-3	neutral	0,24	medium_impact	0,06	medium_impact	0,34	medium_impact	0,67	0,46	0,8	NA	NA	N	0,19	N	0,91	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10123	10123	T	C	MI.15097	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	65	22	F	S	tTt/tCt	3,83	1	0	probably_damaging	0,96	neutral	0,41	neutral	0,91	neutral	-1,04	deleterious	-7,84	medium_impact	2,11	neutral	0,76	damaging	0,11	deleterious	4,16	23,8	0,07	0,35	neutral	0,23	disease	0,81	disease	0,62	disease	0,65	3	neutral	0,96	neutral	0,23	deleterious	1	deleterious	0,71	low_impact	-1,96	medium_impact	0,1	medium_impact	0,83	0,23	0,8	NA	NA	N	0,41	N	0,97	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10123	10123	T	A	MI.15098	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	65	22	F	Y	tTt/tAt	3,83	1	0	probably_damaging	0,95	neutral	1	neutral	0,88	neutral	-1,5	deleterious	-2,95	medium_impact	2,04	neutral	0,76	damaging	0,16	deleterious	4,28	24	0,2	0,45	neutral	0,46	disease	0,75	neutral	0,48	disease	0,53	1	neutral	0,95	deleterious	0,53	deleterious	1	deleterious	0,74	low_impact	-1,87	high_impact	1,85	medium_impact	0,76	0,56	0,8	NA	NA	N	0,44	N	0,89	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10123	10123	T	G	MI.15099	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	65	22	F	C	tTt/tGt	3,83	1	0	probably_damaging	0,99	neutral	0,18	neutral	0,84	deleterious	-3,21	deleterious	-7,82	high_impact	3,78	neutral	0,74	damaging	0,09	deleterious	3,97	23,6	0,08	0,35	disease	0,65	disease	0,87	disease	0,66	disease	0,75	5	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,77	low_impact	-2,52	medium_impact	-0,18	high_impact	2,36	0,16	0,8	NA	NA	P	0,58	P	0,99	polymorphism	1	0,69	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8597	8597	T	G	MI.151	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	71	24	I	S	aTt/aGt	0,36	0,01	0,01	probably_damaging	0,99	neutral	0,18	neutral	3,9	deleterious	-4,47	deleterious	-4,63	low_impact	1,38	neutral	0,82	neutral	0,46	deleterious	4,09	23,7	0,37	0,65	neutral	0,27	disease	0,57	neutral	0,48	neutral	0,48	0	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,67	low_impact	-2,65	medium_impact	-0,08	medium_impact	0,09	0,62	0,9	18,14	17,22	N	0,35	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8397	8397	C	T	MI.1510	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	32	11	T	I	aCc/aTc	-0,33	0	0	probably_damaging	0,99	neutral	0,52	neutral	1,96	neutral	-0,26	neutral	0,28	neutral_impact	0,41	neutral	0,98	neutral	0,97	neutral	1,49	13,26	0,51817131	0,85	neutral	0,1	neutral	0,06	neutral	0,37	neutral	0,04	9	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,64	low_impact	-2,65	medium_impact	0,31	medium_impact	-0,75	0,76	0,85	4,41	7,72	N	0,43	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10124	10124	T	G	MI.15100	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	66	22	F	L	ttT/ttG	4,76	1	0	benign	0,12	neutral	0,65	neutral	1,03	neutral	0,21	deleterious	-5,79	medium_impact	1,94	neutral	0,81	damaging	0,18	deleterious	4,21	23,9	0,3	0,45	neutral	0,31	disease	0,78	neutral	0,46	disease	0,52	0	neutral	0,24	deleterious	0,77	neutral	-3	neutral	0,24	medium_impact	0,06	medium_impact	0,34	medium_impact	0,67	0,46	0,8	NA	NA	N	0,45	N	0,91	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10124	10124	T	A	MI.15101	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	66	22	F	L	ttT/ttA	4,76	1	0	benign	0,12	neutral	0,65	neutral	1,03	neutral	0,21	deleterious	-5,79	medium_impact	1,94	neutral	0,81	damaging	0,18	deleterious	4,24	23,9	0,3	0,45	neutral	0,31	disease	0,78	neutral	0,46	disease	0,52	0	neutral	0,24	deleterious	0,77	neutral	-3	neutral	0,24	medium_impact	0,06	medium_impact	0,34	medium_impact	0,67	0,46	0,8	NA	NA	N	0,45	N	0,91	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10125	10125	T	G	MI.15102	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	67	23	W	G	Tga/Gga	-1,26	0	0	probably_damaging	1	neutral	0,24	neutral	1,01	neutral	-0,24	deleterious	-12,24	medium_impact	3,39	neutral	0,75	damaging	0,08	deleterious	3,77	23,4	0,08	0,35	disease	0,66	disease	0,84	disease	0,76	disease	0,8	6	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,8	low_impact	-3,43	medium_impact	-0,09	high_impact	2	0,11	0,8	5,22	9,13	N	0,42	N	0,97	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10125	10125	T	C	MI.15103	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	67	23	W	R	Tga/Cga	-1,26	0	0	probably_damaging	1	neutral	0,16	neutral	1,01	neutral	-0,54	deleterious	-13,11	medium_impact	3,13	neutral	0,67	damaging	0,05	deleterious	3,43	23	0,07	0,35	disease	0,6	disease	0,93	disease	0,75	disease	0,83	7	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,87	low_impact	-3,43	medium_impact	-0,21	medium_impact	1,76	0,15	0,8	5,22	9,13	N	0,38	N	0,97	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10126	10126	G	T	MI.15104	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	68	23	W	L	tGa/tTa	4,52	1	0	probably_damaging	1	neutral	0,62	neutral	1,28	neutral	2,63	deleterious	-11,96	low_impact	1,31	neutral	0,83	damaging	0,1	deleterious	4,09	23,7	0,11	0,4	neutral	0,14	disease	0,84	disease	0,61	disease	0,52	0	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,74	low_impact	-3,43	medium_impact	0,31	medium_impact	0,09	0,1	0,8	5,22	9,13	N	0,34	N	0,97	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10126	10126	G	C	MI.15105	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	68	23	W	S	tGa/tCa	4,52	1	0	probably_damaging	1	neutral	0,49	neutral	1,06	neutral	0,36	deleterious	-13,07	medium_impact	2,66	neutral	0,79	damaging	0,09	deleterious	3,85	23,4	0,09	0,4	disease	0,51	disease	0,89	disease	0,73	disease	0,8	6	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	0,18	medium_impact	1,33	0,15	0,8	5,22	9,13	N	0,41	N	0,95	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10127	10127	A	C	MI.15106	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	69	23	W	C	tgA/tgC	3,6	1	0	probably_damaging	1	neutral	0,1	neutral	1	neutral	-1,05	deleterious	-12,11	medium_impact	3,25	neutral	0,81	damaging	0,07	deleterious	3,87	23,5	0,08	0,35	disease	0,7	disease	0,88	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	-0,34	medium_impact	1,87	0,15	0,8	5,22	9,13	N	0,5	N	0,98	polymorphism	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10127	10127	A	T	MI.15107	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	69	23	W	C	tgA/tgT	3,6	1	0	probably_damaging	1	neutral	0,1	neutral	1	neutral	-1,05	deleterious	-12,11	medium_impact	3,25	neutral	0,81	damaging	0,07	deleterious	3,98	23,6	0,08	0,35	disease	0,7	disease	0,88	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	-0,34	medium_impact	1,87	0,15	0,8	5,22	9,13	N	0,51	P	0,98	polymorphism	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10128	10128	C	A	MI.15108	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	70	24	L	M	Cta/Ata	1,29	0,58	0	probably_damaging	1	neutral	0,28	neutral	0,64	neutral	-2,91	neutral	-1,77	medium_impact	2,07	neutral	0,73	neutral	0,57	deleterious	3,56	23,1	0,3	0,45	disease	0,53	disease	0,51	neutral	0,31	neutral	0,47	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,74	low_impact	-3,43	medium_impact	-0,04	medium_impact	0,79	0,53	0,8	4,35	7,79	N	0,39	N	0,91	polymorphism	1	0,35	rs377413998	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10128	10128	C	G	MI.15109	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	70	24	L	V	Cta/Gta	1,29	0,58	0	probably_damaging	1	neutral	0,54	neutral	0,74	neutral	-1,44	deleterious	-2,5	medium_impact	2,54	neutral	0,68	neutral	0,41	deleterious	3,31	22,9	0,25	0,45	neutral	0,41	disease	0,59	neutral	0,49	neutral	0,47	1	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,75	low_impact	-3,43	medium_impact	0,23	medium_impact	1,22	0,29	0,8	4,35	7,79	N	0,28	N	0,89	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8397	8397	C	G	MI.1511	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	32	11	T	S	aCc/aGc	-0,33	0	0	probably_damaging	0,97	neutral	0,49	neutral	1,84	neutral	-1,87	neutral	-2,12	low_impact	1,36	neutral	1	neutral	0,63	deleterious	2,13	17,03	0,52918828	0,85	neutral	0,42	neutral	0,16	neutral	0,49	neutral	0,12	8	neutral	0,97	neutral	0,26	neutral	-2	deleterious	0,66	low_impact	-2,19	medium_impact	0,28	medium_impact	0,07	0,72	0,85	4,41	7,72	N	0,44	N	0,43	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10129	10129	T	A	MI.15110	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	71	24	L	Q	cTa/cAa	-1,26	0	0	probably_damaging	1	neutral	0,35	neutral	0,61	deleterious	-3,9	deleterious	-5,7	high_impact	4,12	neutral	0,61	damaging	0,23	deleterious	4,12	23,8	0,07	0,35	disease	0,79	disease	0,79	disease	0,64	disease	0,74	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-3,43	medium_impact	0,04	high_impact	2,67	0,18	0,8	4,35	7,79	N	0,34	N	0,97	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10129	10129	T	G	MI.15111	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	71	24	L	R	cTa/cGa	-1,26	0	0	probably_damaging	1	neutral	0,39	neutral	0,61	deleterious	-3,76	deleterious	-5,74	high_impact	4,46	neutral	0,66	damaging	0,18	deleterious	4,06	23,7	0,04	0,35	disease	0,77	disease	0,9	disease	0,75	disease	0,83	7	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,9	low_impact	-3,43	medium_impact	0,08	high_impact	2,98	0,2	0,8	4,35	7,79	N	0,46	N	1	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10129	10129	T	C	MI.15112	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	71	24	L	P	cTa/cCa	-1,26	0	0	probably_damaging	1	neutral	0,24	neutral	0,59	deleterious	-4,66	deleterious	-6,62	high_impact	3,91	damaging	0,58	damaging	0,22	deleterious	3,82	23,4	0,04	0,35	disease	0,84	disease	0,84	disease	0,76	disease	0,83	7	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-3,43	medium_impact	-0,09	high_impact	2,48	0,23	0,8	4,35	7,79	N	0,36	N	0,99	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10131	10131	C	G	MI.15113	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	73	25	P	A	Cca/Gca	-20	0	0	probably_damaging	1	neutral	0,34	neutral	1,07	neutral	1,34	deleterious	-7,94	low_impact	1,74	neutral	0,73	neutral	0,39	deleterious	2,92	21,9	0,33	0,5	neutral	0,23	neutral	0,43	neutral	0,44	neutral	0,38	2	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,7	low_impact	-3,43	medium_impact	0,03	medium_impact	0,49	0,57	0,8	1,74	6,78	N	0,43	N	0,81	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10131	10131	C	A	MI.15114	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	73	25	P	T	Cca/Aca	-20	0	0	probably_damaging	1	neutral	0,25	neutral	1,04	neutral	0,81	deleterious	-7,94	medium_impact	2,23	neutral	0,74	damaging	0,16	deleterious	3,55	23,1	0,3	0,45	neutral	0,38	disease	0,74	neutral	0,32	disease	0,51	0	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,74	low_impact	-3,43	medium_impact	-0,08	medium_impact	0,94	0,38	0,8	1,74	6,78	N	0,35	N	0,97	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10131	10131	C	T	MI.15115	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	73	25	P	S	Cca/Tca	-20	0	0	probably_damaging	1	neutral	0,29	neutral	1,16	neutral	2,17	deleterious	-7,94	low_impact	1,5	neutral	0,75	damaging	0,2	deleterious	3,77	23,4	0,28	0,45	neutral	0,16	disease	0,75	neutral	0,3	neutral	0,5	0	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,71	low_impact	-3,43	medium_impact	-0,03	medium_impact	0,27	0,27	0,8	1,74	6,78	N	0,34	N	0,95	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10132	10132	C	G	MI.15116	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	74	25	P	R	cCa/cGa	1,29	0,74	0	probably_damaging	1	neutral	0,25	neutral	1,06	neutral	1,1	deleterious	-8,93	medium_impact	2,22	neutral	0,66	damaging	0,05	deleterious	3,4	23	0,14	0,4	disease	0,58	disease	0,91	disease	0,61	disease	0,74	5	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,84	low_impact	-3,43	medium_impact	-0,08	medium_impact	0,93	0,43	0,8	1,74	6,78	N	0,31	N	0,73	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10132	10132	C	T	MI.15117	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	74	25	P	L	cCa/cTa	1,29	0,74	0	probably_damaging	1	neutral	1	neutral	1	neutral	-0,02	deleterious	-9,92	medium_impact	3,22	neutral	0,68	damaging	0,04	deleterious	4,2	23,9	0,14	0,4	disease	0,58	disease	0,88	disease	0,52	disease	0,72	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,81	low_impact	-3,43	high_impact	1,85	medium_impact	1,84	0,48	0,8	1,74	6,78	N	0,31	N	0,97	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10132	10132	C	A	MI.15118	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	74	25	P	Q	cCa/cAa	1,29	0,74	0	probably_damaging	1	neutral	0,2	neutral	1,03	neutral	0,76	deleterious	-7,94	medium_impact	3,13	neutral	0,73	damaging	0,05	deleterious	3,98	23,6	0,21	0,45	disease	0,58	disease	0,83	neutral	0,5	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,79	low_impact	-3,43	medium_impact	-0,14	medium_impact	1,76	0,32	0,8	1,74	6,78	N	0,34	N	0,9	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10134	10134	C	A	MI.15119	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	76	26	Q	K	Caa/Aaa	-6,81	0	0	benign	0,43	neutral	0,74	neutral	1	neutral	0,78	deleterious	-3,8	low_impact	1,18	neutral	0,69	damaging	0,08	deleterious	3,88	23,5	0,29	0,45	neutral	0,13	disease	0,84	neutral	0,25	neutral	0,48	0	neutral	0,33	deleterious	0,66	neutral	-6	deleterious	0,51	medium_impact	-0,61	medium_impact	0,44	medium_impact	-0,03	0,33	0,8	NA	NA	N	0,19	N	0,96	disease_causing_automatic	0	0,49	rs587780529	Pathogenic	Leigh_syndrome	RCV000144458.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	8397	8397	C	A	MI.1512	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	32	11	T	N	aCc/aAc	-0,33	0	0	probably_damaging	0,99	neutral	0,37	neutral	1,79	deleterious	-3,45	deleterious	-3,12	medium_impact	2,27	neutral	0,99	neutral	0,62	deleterious	3,38	22,9	0,52641227	0,85	disease	0,6	neutral	0,27	disease	0,6	neutral	0,13	7	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,72	low_impact	-2,65	medium_impact	0,16	medium_impact	0,85	0,83	0,85	4,41	7,72	N	0,5	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10134	10134	C	G	MI.15120	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	76	26	Q	E	Caa/Gaa	-6,81	0	0	benign	0,43	neutral	0,7	neutral	0,98	neutral	0,35	deleterious	-2,85	medium_impact	2,19	neutral	0,73	damaging	0,12	deleterious	2,98	22,2	0,35	0,5	neutral	0,28	disease	0,8	neutral	0,38	disease	0,63	3	neutral	0,34	deleterious	0,64	neutral	-3	deleterious	0,53	medium_impact	-0,61	medium_impact	0,39	medium_impact	0,9	0,45	0,8	NA	NA	N	0,19	N	0,93	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10135	10135	A	T	MI.15121	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	77	26	Q	L	cAa/cTa	1,52	0,01	0	benign	0,03	neutral	0,83	neutral	0,92	neutral	-0,77	deleterious	-6,58	low_impact	1,83	neutral	0,78	neutral	0,33	deleterious	3,48	23,1	0,16	0,45	neutral	0,46	disease	0,8	neutral	0,35	disease	0,53	1	neutral	0,11	deleterious	0,9	neutral	-6	neutral	0,26	medium_impact	0,65	medium_impact	0,57	medium_impact	0,57	0,18	0,8	NA	NA	N	0,22	N	0,97	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10135	10135	A	C	MI.15122	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	77	26	Q	P	cAa/cCa	1,52	0,01	0	possibly_damaging	0,8	neutral	0,48	neutral	0,96	neutral	0,49	deleterious	-5,74	low_impact	1,15	neutral	0,65	damaging	0,08	deleterious	3,17	22,7	0,12	0,4	disease	0,57	disease	0,92	neutral	0,4	disease	0,68	4	neutral	0,79	neutral	0,34	neutral	-3	deleterious	0,78	low_impact	-1,26	medium_impact	0,17	medium_impact	-0,05	0,3	0,8	NA	NA	N	0,26	N	0,96	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10135	10135	A	G	MI.15123	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	77	26	Q	R	cAa/cGa	1,52	0,01	0	possibly_damaging	0,63	neutral	0,56	neutral	0,93	neutral	0,11	deleterious	-3,78	medium_impact	1,98	neutral	0,66	damaging	0,09	deleterious	3,27	22,8	0,29	0,45	neutral	0,25	disease	0,89	neutral	0,43	disease	0,75	5	neutral	0,58	neutral	0,47	NA	0	deleterious	0,66	medium_impact	-0,93	medium_impact	0,25	medium_impact	0,71	0,33	0,8	NA	NA	N	0,26	N	0,85	polymorphism	1	0,49	rs28754574	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10136	10136	A	T	MI.15124	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	78	26	Q	H	caA/caT	1,75	0,01	0	probably_damaging	0,93	neutral	0,58	neutral	0,89	neutral	-1,31	deleterious	-4,52	low_impact	1,53	neutral	0,83	neutral	0,73	deleterious	2,33	18,35	0,22	0,45	disease	0,5	disease	0,79	neutral	0,28	neutral	0,48	0	neutral	0,92	neutral	0,33	neutral	-2	deleterious	0,77	low_impact	-1,73	medium_impact	0,27	medium_impact	0,29	0,41	0,8	NA	NA	N	0,24	N	0,93	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10136	10136	A	C	MI.15125	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	78	26	Q	H	caA/caC	1,75	0,01	0	probably_damaging	0,93	neutral	0,58	neutral	0,89	neutral	-1,31	deleterious	-4,52	low_impact	1,53	neutral	0,83	neutral	0,73	deleterious	2,18	17,39	0,22	0,45	disease	0,5	disease	0,79	neutral	0,28	neutral	0,48	0	neutral	0,92	neutral	0,33	neutral	-2	deleterious	0,77	low_impact	-1,73	medium_impact	0,27	medium_impact	0,29	0,41	0,8	NA	NA	N	0,24	N	0,93	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10137	10137	C	G	MI.15126	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	79	27	L	V	Ctc/Gtc	0,13	0	0	probably_damaging	1	neutral	0,5	neutral	1	neutral	-0,13	neutral	-2,09	low_impact	1,86	neutral	0,83	neutral	0,33	deleterious	3,25	22,8	0,36	0,5	neutral	0,26	neutral	0,47	neutral	0,38	neutral	0,5	0	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,68	low_impact	-3,43	medium_impact	0,19	medium_impact	0,6	0,4	0,8	2,61	7,38	N	0,27	N	0,42	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10137	10137	C	A	MI.15127	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	79	27	L	I	Ctc/Atc	0,13	0	0	probably_damaging	1	neutral	0,42	neutral	0,98	neutral	-0,95	neutral	-1,38	low_impact	0,95	neutral	0,85	neutral	0,58	deleterious	2,96	22,1	0,3	0,45	neutral	0,27	neutral	0,33	neutral	0,2	neutral	0,45	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,68	low_impact	-3,43	medium_impact	0,11	medium_impact	-0,24	0,33	0,8	2,61	7,38	N	0,35	N	0,52	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10137	10137	C	T	MI.15128	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	79	27	L	F	Ctc/Ttc	0,13	0	0	probably_damaging	1	neutral	0,69	neutral	0,99	neutral	-0,49	deleterious	-3,25	low_impact	1,94	neutral	0,75	damaging	0,09	deleterious	3,79	23,4	0,32	0,5	neutral	0,41	disease	0,56	neutral	0,41	disease	0,51	0	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,73	low_impact	-3,43	medium_impact	0,38	medium_impact	0,67	0,34	0,8	2,61	7,38	N	0,21	N	0,65	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10138	10138	T	C	MI.15129	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	80	27	L	P	cTc/cCc	-0,8	0	0	probably_damaging	1	neutral	0,22	neutral	0,98	neutral	-0,81	deleterious	-5,46	low_impact	1,9	neutral	0,79	neutral	0,4	deleterious	3,8	23,4	0,08	0,35	disease	0,62	disease	0,84	neutral	0,44	disease	0,72	4	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,84	low_impact	-3,43	medium_impact	-0,12	medium_impact	0,63	0,25	0,8	2,61	7,38	N	0,27	N	0,94	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8399	8399	A	G	MI.1513	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	34	12	M	V	Ata/Gta	-7,74	0	0	benign	0	neutral	0,26	neutral	2,02	neutral	0,25	neutral	0,46	neutral_impact	-1,28	neutral	1	neutral	0,94	neutral	-1,26	0,01	0,62618842	0,85	neutral	0,26	neutral	0,21	neutral	0,46	neutral	0,11	8	neutral	0,74	deleterious	0,63	neutral	-6	neutral	0,17	high_impact	2,09	medium_impact	0,04	low_impact	-2,19	0,6	0,85	NA	NA	N	0,45	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10138	10138	T	A	MI.15130	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	80	27	L	H	cTc/cAc	-0,8	0	0	probably_damaging	1	neutral	0,53	neutral	0,99	neutral	-0,33	deleterious	-5,82	low_impact	1,47	neutral	0,72	damaging	0,07	deleterious	4,17	23,8	0,17	0,45	disease	0,59	disease	0,67	neutral	0,42	disease	0,52	0	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,77	low_impact	-3,43	medium_impact	0,22	medium_impact	0,24	0,15	0,8	2,61	7,38	N	0,21	N	0,86	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10138	10138	T	G	MI.15131	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	80	27	L	R	cTc/cGc	-0,8	0	0	probably_damaging	1	neutral	0,34	neutral	1,05	neutral	1,08	deleterious	-4,99	neutral_impact	0,43	neutral	0,69	damaging	0,05	deleterious	4,13	23,8	0,12	0,4	neutral	0,41	disease	0,84	neutral	0,33	disease	0,56	1	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,8	low_impact	-3,43	medium_impact	0,03	medium_impact	-0,71	0,21	0,8	2,61	7,38	N	0,22	N	0,97	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10140	10140	A	G	MI.15132	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	82	28	N	D	Aac/Gac	-1,95	0	0	possibly_damaging	0,72	neutral	0,27	neutral	0,94	neutral	-0,69	deleterious	-3,89	medium_impact	2,21	neutral	0,85	damaging	0,2	deleterious	3,36	22,9	0,68	0,7	neutral	0,34	disease	0,67	neutral	0,47	disease	0,51	0	neutral	0,8	neutral	0,28	NA	0	deleterious	0,6	low_impact	-1,09	medium_impact	-0,05	medium_impact	0,92	0,35	0,8	3,48	9,24	N	0,38	N	0,77	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10140	10140	A	T	MI.15133	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	82	28	N	Y	Aac/Tac	-1,95	0	0	benign	0,08	neutral	1	neutral	0,88	neutral	-2,49	deleterious	-4,68	low_impact	1,68	neutral	0,86	neutral	0,87	deleterious	0,53	7,68	0,26	0,45	disease	0,61	disease	0,74	neutral	0,33	disease	0,53	1	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,27	medium_impact	0,24	high_impact	1,85	medium_impact	0,43	0,23	0,8	3,48	9,24	N	0,21	N	0,08	polymorphism	1	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10140	10140	A	C	MI.15134	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	82	28	N	H	Aac/Cac	-1,95	0	0	possibly_damaging	0,87	neutral	0,53	neutral	0,88	neutral	-1,68	deleterious	-3,16	medium_impact	2,48	neutral	0,84	neutral	0,3	deleterious	2,65	20,5	0,58	0,65	disease	0,53	disease	0,67	neutral	0,35	disease	0,53	1	neutral	0,86	neutral	0,33	NA	0	deleterious	0,7	low_impact	-1,46	medium_impact	0,22	medium_impact	1,17	0,14	0,8	3,48	9,24	N	0,28	N	0,42	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10141	10141	A	G	MI.15135	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	83	28	N	S	aAc/aGc	0,59	0	0	benign	0,15	neutral	0,54	neutral	1	neutral	0,13	deleterious	-3,51	low_impact	1,01	neutral	0,78	neutral	0,4	deleterious	0,24	5,05	0,75	0,8	neutral	0,26	neutral	0,4	neutral	0,29	neutral	0,44	1	neutral	0,36	deleterious	0,7	neutral	-6	neutral	0,2	medium_impact	-0,04	medium_impact	0,23	medium_impact	-0,18	0,39	0,8	3,48	9,24	N	0,26	N	0,61	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10141	10141	A	T	MI.15136	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	83	28	N	I	aAc/aTc	0,59	0	0	possibly_damaging	0,88	neutral	0,41	neutral	0,87	neutral	-1,72	deleterious	-6,72	medium_impact	1,97	neutral	0,84	damaging	0,19	deleterious	3,58	23,2	0,28	0,45	disease	0,5	disease	0,81	neutral	0,41	disease	0,67	3	neutral	0,88	neutral	0,27	NA	0	deleterious	0,72	low_impact	-1,5	medium_impact	0,1	medium_impact	0,7	0,33	0,8	3,48	9,24	N	0,29	N	0,9	polymorphism	1	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10141	10141	A	C	MI.15137	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	83	28	N	T	aAc/aCc	0,59	0	0	possibly_damaging	0,64	neutral	0,45	neutral	0,94	neutral	-0,5	deleterious	-4,36	medium_impact	2,02	neutral	0,81	neutral	0,36	neutral	1,78	14,86	0,53	0,6	neutral	0,21	neutral	0,41	neutral	0,26	neutral	0,44	1	neutral	0,64	neutral	0,41	NA	0	deleterious	0,49	medium_impact	-0,94	medium_impact	0,14	medium_impact	0,74	0,28	0,8	3,48	9,24	N	0,31	N	0,65	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10142	10142	C	A	MI.15138	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	84	28	N	K	aaC/aaA	0,36	0	0	possibly_damaging	0,72	neutral	0,53	neutral	1,04	neutral	0,68	deleterious	-4,46	low_impact	1,5	neutral	0,81	neutral	0,34	deleterious	4	23,6	0,56	0,6	neutral	0,29	disease	0,66	neutral	0,34	neutral	0,47	1	neutral	0,69	neutral	0,41	neutral	-3	deleterious	0,61	low_impact	-1,09	medium_impact	0,22	medium_impact	0,27	0,46	0,8	3,48	9,24	N	0,23	N	0,82	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10142	10142	C	G	MI.15139	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	84	28	N	K	aaC/aaG	0,36	0	0	possibly_damaging	0,72	neutral	0,53	neutral	1,04	neutral	0,68	deleterious	-4,46	low_impact	1,5	neutral	0,81	neutral	0,34	deleterious	3,49	23,1	0,56	0,6	neutral	0,29	disease	0,66	neutral	0,34	neutral	0,47	1	neutral	0,69	neutral	0,41	neutral	-3	deleterious	0,61	low_impact	-1,09	medium_impact	0,22	medium_impact	0,27	0,46	0,8	3,48	9,24	N	0,23	N	0,82	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8399	8399	A	C	MI.1514	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	34	12	M	L	Ata/Cta	-7,74	0	0	benign	0	neutral	0,89	neutral	2,06	neutral	0,75	neutral	-0,42	neutral_impact	0,27	neutral	0,99	neutral	0,44	neutral	-0,87	0,03	0,54903459	0,85	neutral	0,25	neutral	0,25	disease	0,59	neutral	0,13	7	neutral	0,1	deleterious	0,95	neutral	-6	neutral	0,17	high_impact	2,09	medium_impact	0,8	medium_impact	-0,87	0,65	0,85	NA	NA	N	0,34	N	0,38	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10143	10143	G	A	MI.15140	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	85	29	G	S	Ggc/Agc	-2,42	0	0	benign	0	neutral	0,92	neutral	1,06	neutral	0,43	neutral	1,97	neutral_impact	-0,84	neutral	0,89	neutral	0,95	deleterious	0,28	5,51	0,31	0,45	neutral	0,11	neutral	0,34	neutral	0,23	neutral	0,43	1	neutral	0,07	deleterious	0,96	neutral	-6	neutral	0,12	medium_impact	1,99	medium_impact	0,78	low_impact	-1,88	0,48	0,8	20	10,89	N	0,2	N	0,02	polymorphism	1	0,15	rs202131419	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10143	10143	G	C	MI.15141	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	85	29	G	R	Ggc/Cgc	-2,42	0	0	benign	0,14	neutral	0,59	neutral	1,03	neutral	0,26	neutral	0,76	neutral_impact	-0,14	neutral	0,7	neutral	0,51	deleterious	0,57	7,93	0,16	0,45	neutral	0,2	disease	0,76	disease	0,53	disease	0,67	3	neutral	0,3	deleterious	0,73	neutral	-6	neutral	0,26	medium_impact	-0,01	medium_impact	0,28	low_impact	-1,24	0,5	0,8	20	10,89	N	0,27	N	0,1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10143	10143	G	T	MI.15142	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	85	29	G	C	Ggc/Tgc	-2,42	0	0	possibly_damaging	0,62	neutral	0,09	neutral	0,96	deleterious	-3,13	neutral	1,5	low_impact	1,04	neutral	0,68	neutral	0,42	deleterious	2,55	19,78	0,12	0,4	neutral	0,38	disease	0,7	neutral	0,5	disease	0,52	0	neutral	0,91	neutral	0,24	neutral	-3	deleterious	0,46	medium_impact	-0,91	medium_impact	-0,37	medium_impact	-0,16	0,16	0,8	20	10,89	N	0,37	N	0,15	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10144	10144	G	C	MI.15143	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	86	29	G	A	gGc/gCc	-1,95	0	0	benign	0,02	neutral	0,83	neutral	1,06	neutral	0,36	neutral	2,31	neutral_impact	-0,38	neutral	0,78	neutral	0,9	neutral	-0,59	0,13	0,29	0,45	neutral	0,11	neutral	0,34	neutral	0,34	neutral	0,43	1	neutral	0,13	deleterious	0,91	neutral	-6	neutral	0,13	medium_impact	0,81	medium_impact	0,57	low_impact	-1,46	0,28	0,8	20	10,89	N	0,22	N	0,06	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10144	10144	G	T	MI.15144	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	86	29	G	V	gGc/gTc	-1,95	0	0	benign	0,06	neutral	0,43	neutral	1,01	neutral	-0,59	neutral	3,54	neutral_impact	-0,48	neutral	0,83	neutral	0,96	deleterious	0,32	5,92	0,14	0,4	neutral	0,11	disease	0,55	neutral	0,4	neutral	0,44	1	neutral	0,52	deleterious	0,69	neutral	-6	neutral	0,16	medium_impact	0,36	medium_impact	0,12	low_impact	-1,55	0,21	0,8	20	10,89	N	0,25	N	0,05	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10144	10144	G	A	MI.15145	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	86	29	G	D	gGc/gAc	-1,95	0	0	benign	0,06	neutral	0,67	neutral	1,02	neutral	-0,19	neutral	0,34	neutral_impact	0,18	neutral	0,66	neutral	0,5	deleterious	0,4	6,58	0,14	0,4	neutral	0,25	disease	0,69	disease	0,58	disease	0,67	3	neutral	0,25	deleterious	0,81	neutral	-6	neutral	0,21	medium_impact	0,36	medium_impact	0,36	medium_impact	-0,94	0,23	0,8	20	10,89	N	0,28	N	0,26	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10146	10146	T	A	MI.15146	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	88	30	Y	N	Tac/Aac	-13,06	0	0	probably_damaging	1	neutral	0,5	neutral	1,05	neutral	1,43	deleterious	-7,53	low_impact	1,03	neutral	0,77	neutral	0,34	neutral	1,26	12,08	0,31	0,5	neutral	0,4	disease	0,76	neutral	0,44	disease	0,55	1	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,77	low_impact	-3,43	medium_impact	0,19	medium_impact	-0,16	0,2	0,8	NA	NA	N	0,29	N	0,99	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10146	10146	T	C	MI.15147	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	88	30	Y	H	Tac/Cac	-13,06	0	0	probably_damaging	1	neutral	0,57	neutral	0,98	neutral	-0,53	deleterious	-4,11	medium_impact	2,98	neutral	0,72	damaging	0,08	deleterious	2,24	17,76	0,45	0,55	disease	0,55	disease	0,6	disease	0,57	disease	0,69	4	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,78	low_impact	-3,43	medium_impact	0,26	medium_impact	1,62	0,17	0,8	NA	NA	N	0,21	N	0,98	polymorphism	1	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10146	10146	T	G	MI.15148	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	88	30	Y	D	Tac/Gac	-13,06	0	0	probably_damaging	1	neutral	0,47	neutral	1,05	neutral	1,13	deleterious	-8,04	neutral_impact	0,52	neutral	0,65	neutral	0,44	neutral	1,33	12,43	0,19	0,45	neutral	0,1	neutral	0,12	neutral	0,42	neutral	0,26	5	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,64	low_impact	-3,43	medium_impact	0,16	medium_impact	-0,63	0,21	0,8	NA	NA	N	0,34	N	0,97	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10147	10147	A	G	MI.15149	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	89	30	Y	C	tAc/tGc	3,6	1	0	probably_damaging	1	neutral	0,19	neutral	0,96	neutral	-2,76	deleterious	-8,01	high_impact	3,67	neutral	0,67	damaging	0,07	deleterious	3,4	23	0,17	0,45	disease	0,81	disease	0,83	disease	0,65	disease	0,79	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,43	medium_impact	-0,16	high_impact	2,26	0,05	0,8	NA	NA	N	0,52	P	1	polymorphism	1	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8399	8399	A	T	MI.1515	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	34	12	M	L	Ata/Tta	-7,74	0	0	benign	0	neutral	0,89	neutral	2,06	neutral	0,75	neutral	-0,42	neutral_impact	0,27	neutral	0,99	neutral	0,44	neutral	-0,69	0,08	0,54903459	0,85	neutral	0,25	neutral	0,25	disease	0,59	neutral	0,13	7	neutral	0,1	deleterious	0,95	neutral	-6	neutral	0,17	high_impact	2,09	medium_impact	0,8	medium_impact	-0,87	0,65	0,85	NA	NA	N	0,35	N	0,38	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10147	10147	A	C	MI.15150	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	89	30	Y	S	tAc/tCc	3,6	1	0	probably_damaging	1	neutral	0,69	neutral	1,09	neutral	1,49	deleterious	-7,68	low_impact	1,23	neutral	0,8	damaging	0,15	deleterious	1,85	15,26	0,21	0,45	neutral	0,4	disease	0,7	neutral	0,47	disease	0,52	0	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,77	low_impact	-3,43	medium_impact	0,38	medium_impact	0,02	0,21	0,8	NA	NA	N	0,34	N	0,98	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10147	10147	A	T	MI.15151	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	89	30	Y	F	tAc/tTc	3,6	1	0	probably_damaging	1	neutral	0,72	neutral	0,98	neutral	-1,37	deleterious	-3,58	medium_impact	2,98	neutral	0,68	damaging	0,11	deleterious	3,39	23	0,45	0,55	neutral	0,41	disease	0,63	disease	0,58	disease	0,65	3	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,76	low_impact	-3,43	medium_impact	0,42	medium_impact	1,62	0,08	0,8	NA	NA	N	0,46	N	0,81	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10149	10149	A	C	MI.15152	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	91	31	M	L	Ata/Cta	-2,19	0	0	benign	0,08	neutral	0,42	neutral	1,06	neutral	1,1	neutral	-0,4	neutral_impact	-0,65	neutral	0,85	neutral	0,91	neutral	1,73	14,59	0,36	0,5	neutral	0,14	neutral	0,37	neutral	0,35	neutral	0,42	2	neutral	0,53	deleterious	0,67	neutral	-6	neutral	0,16	medium_impact	0,24	medium_impact	0,11	low_impact	-1,71	0,25	0,8	11,3	7,82	N	0,29	N	0,44	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10149	10149	A	G	MI.15153	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	91	31	M	V	Ata/Gta	-2,19	0	0	benign	0,01	neutral	0,33	neutral	1,03	neutral	0,99	neutral	-0,21	neutral_impact	0,03	neutral	0,82	neutral	0,76	neutral	1,32	12,38	0,32	0,5	neutral	0,15	neutral	0,37	neutral	0,41	neutral	0,43	1	neutral	0,66	deleterious	0,66	neutral	-6	neutral	0,1	medium_impact	1,09	medium_impact	0,02	low_impact	-1,08	0,22	0,8	11,3	7,82	N	0,33	N	0,43	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10149	10149	A	T	MI.15154	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	91	31	M	L	Ata/Tta	-2,19	0	0	benign	0,08	neutral	0,42	neutral	1,06	neutral	1,1	neutral	-0,4	neutral_impact	-0,65	neutral	0,85	neutral	0,91	neutral	1,77	14,78	0,36	0,5	neutral	0,14	neutral	0,37	neutral	0,35	neutral	0,42	2	neutral	0,53	deleterious	0,67	neutral	-6	neutral	0,16	medium_impact	0,24	medium_impact	0,11	low_impact	-1,71	0,25	0,8	11,3	7,82	N	0,29	N	0,44	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10150	10150	T	C	MI.15155	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	92	31	M	T	aTa/aCa	-8,2	0	0	benign	0,01	neutral	0,62	neutral	1,06	neutral	1,86	neutral	1,03	neutral_impact	-1,38	neutral	0,88	neutral	0,99	deleterious	0,17	4,39	0,18	0,45	neutral	0,11	neutral	0,22	neutral	0,31	neutral	0,38	3	neutral	0,36	deleterious	0,81	neutral	-6	neutral	0,09	medium_impact	1,09	medium_impact	0,31	low_impact	-2,37	0,05	0,8	11,3	7,82	N	0,3	N	0,03	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10150	10150	T	A	MI.15156	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	92	31	M	K	aTa/aAa	-8,2	0	0	benign	0,31	neutral	0,98	neutral	1,12	neutral	2,72	neutral	-1,03	neutral_impact	-0,14	neutral	0,77	neutral	0,48	deleterious	3,87	23,5	0,14	0,4	neutral	0,14	disease	0,6	neutral	0,45	disease	0,53	1	neutral	0,27	deleterious	0,84	neutral	-6	neutral	0,36	medium_impact	-0,4	medium_impact	1,13	low_impact	-1,24	0,24	0,8	11,3	7,82	N	0,25	N	0,56	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10151	10151	A	T	MI.15157	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	93	31	M	I	atA/atT	0,13	0	0	benign	0,1	neutral	0,19	neutral	1,02	neutral	0,36	neutral	-0,59	neutral_impact	0,34	neutral	0,8	neutral	0,64	deleterious	2,34	18,42	0,25	0,45	neutral	0,18	neutral	0,33	neutral	0,4	neutral	0,44	1	neutral	0,79	deleterious	0,55	neutral	-6	neutral	0,19	medium_impact	0,15	medium_impact	-0,16	medium_impact	-0,8	0,26	0,8	11,3	7,82	N	0,37	N	0,37	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10151	10151	A	C	MI.15158	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	93	31	M	I	atA/atC	0,13	0	0	benign	0,1	neutral	0,19	neutral	1,02	neutral	0,36	neutral	-0,59	neutral_impact	0,34	neutral	0,8	neutral	0,64	deleterious	2,25	17,86	0,25	0,45	neutral	0,18	neutral	0,33	neutral	0,4	neutral	0,44	1	neutral	0,79	deleterious	0,55	neutral	-6	neutral	0,19	medium_impact	0,15	medium_impact	-0,16	medium_impact	-0,8	0,26	0,8	11,3	7,82	N	0,37	N	0,37	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10152	10152	G	A	MI.15159	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	94	32	E	K	Gaa/Aaa	-0,57	0	0	probably_damaging	1	neutral	0,94	neutral	0,85	neutral	-1,16	deleterious	-3,91	high_impact	3,5	damaging	0,59	damaging	0,07	deleterious	4,44	24,2	0,15	0,4	neutral	0,43	disease	0,89	disease	0,73	disease	0,73	5	deleterious	1	deleterious	0,47	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	0,85	high_impact	2,1	0,52	0,8	2,61	6,78	N	0,35	N	0,9	polymorphism	1	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8400	8400	T	A	MI.1516	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	35	12	M	K	aTa/aAa	3,14	0,03	0	benign	0,01	neutral	0,09	neutral	1,92	neutral	-2,67	neutral	-2,2	low_impact	1,24	neutral	0,99	neutral	0,36	deleterious	0,77	9,27	0,20000037	0,85	neutral	0,33	neutral	0,46	disease	0,69	neutral	0,26	5	neutral	0,91	deleterious	0,54	neutral	-6	neutral	0,24	medium_impact	1,14	medium_impact	-0,28	medium_impact	-0,04	0,59	0,85	NA	NA	N	0,56	P	0,56	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10152	10152	G	C	MI.15160	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	94	32	E	Q	Gaa/Caa	-0,57	0	0	probably_damaging	1	neutral	0,55	neutral	0,81	neutral	-1,69	deleterious	-2,9	medium_impact	3,06	damaging	0,59	damaging	0,14	deleterious	3,22	22,7	0,51	0,6	neutral	0,37	disease	0,75	disease	0,62	neutral	0,49	0	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,79	low_impact	-3,43	medium_impact	0,24	medium_impact	1,7	0,39	0,8	2,61	6,78	N	0,28	N	0,81	polymorphism	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10153	10153	A	G	MI.15161	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	95	32	E	G	gAa/gGa	7,3	1	0	probably_damaging	1	neutral	0,29	neutral	0,77	neutral	-2,46	deleterious	-6,76	medium_impact	3,38	damaging	0,54	damaging	0,15	deleterious	3,98	23,6	0,27	0,45	disease	0,53	disease	0,78	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	-0,03	medium_impact	1,99	0,21	0,8	2,61	6,78	P	0,59	P	0,85	polymorphism	1	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10153	10153	A	C	MI.15162	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	95	32	E	A	gAa/gCa	7,3	1	0	probably_damaging	1	neutral	0,61	neutral	0,82	neutral	-1,5	deleterious	-5,84	medium_impact	2,88	neutral	0,62	damaging	0,1	deleterious	3,45	23	0,21	0,45	neutral	0,48	disease	0,8	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	0,3	medium_impact	1,53	0,42	0,8	2,61	6,78	N	0,5	N	0,81	polymorphism	1	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10153	10153	A	T	MI.15163	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	95	32	E	V	gAa/gTa	7,3	1	0	probably_damaging	1	neutral	0,21	neutral	0,76	neutral	-2,64	deleterious	-6,83	medium_impact	3,29	damaging	0,58	damaging	0,08	deleterious	3,94	23,5	0,13	0,4	disease	0,69	disease	0,89	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,87	low_impact	-3,43	medium_impact	-0,13	medium_impact	1,91	0,44	0,8	2,61	6,78	P	0,59	P	0,94	polymorphism	1	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10154	10154	A	T	MI.15164	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	96	32	E	D	gaA/gaT	8,69	1	0	probably_damaging	1	neutral	0,75	neutral	0,82	neutral	-1,48	deleterious	-2,68	medium_impact	2,94	neutral	0,68	neutral	0,66	deleterious	3,71	23,3	0,5	0,6	neutral	0,28	disease	0,72	neutral	0,47	neutral	0,46	1	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,76	low_impact	-3,43	medium_impact	0,45	medium_impact	1,59	0,27	0,8	2,61	6,78	P	0,59	P	0,23	polymorphism	1	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10154	10154	A	C	MI.15165	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	96	32	E	D	gaA/gaC	8,69	1	0	probably_damaging	1	neutral	0,75	neutral	0,82	neutral	-1,48	deleterious	-2,68	medium_impact	2,94	neutral	0,68	neutral	0,66	deleterious	3,58	23,2	0,5	0,6	neutral	0,28	disease	0,72	neutral	0,47	neutral	0,46	1	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,76	low_impact	-3,43	medium_impact	0,45	medium_impact	1,59	0,27	0,8	2,61	6,78	P	0,58	P	0,23	polymorphism	1	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10155	10155	A	G	MI.15166	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	97	33	K	E	Aaa/Gaa	1,75	1	0	probably_damaging	1	neutral	1	neutral	0,7	deleterious	-3,82	deleterious	-3,97	high_impact	3,71	damaging	0,57	damaging	0,04	deleterious	3,68	23,3	0,12	0,4	disease	0,61	disease	0,84	disease	0,76	disease	0,69	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,85	low_impact	-3,43	high_impact	1,85	high_impact	2,29	0,37	0,8	1,74	6,56	N	0,47	N	0,86	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10155	10155	A	C	MI.15167	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	97	33	K	Q	Aaa/Caa	1,75	1	0	probably_damaging	1	neutral	0,4	neutral	0,68	deleterious	-3,96	deleterious	-3,97	high_impact	4,32	damaging	0,57	damaging	0,05	deleterious	3,14	22,6	0,2	0,45	disease	0,61	disease	0,81	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,82	low_impact	-3,43	medium_impact	0,09	high_impact	2,85	0,46	0,8	1,74	6,56	P	0,55	P	0,86	polymorphism	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10156	10156	A	C	MI.15168	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	98	33	K	T	aAa/aCa	5,68	1	0	probably_damaging	1	neutral	0,41	neutral	0,67	deleterious	-4,26	deleterious	-5,96	high_impact	3,58	damaging	0,55	damaging	0,04	deleterious	3,46	23	0,07	0,35	disease	0,7	disease	0,88	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	0,1	high_impact	2,17	0,32	0,8	1,74	6,56	P	0,62	P	0,81	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10156	10156	A	T	MI.15169	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	98	33	K	M	aAa/aTa	5,68	1	0	probably_damaging	1	neutral	0,12	neutral	0,63	deleterious	-6,05	deleterious	-5,96	high_impact	3,97	damaging	0,58	damaging	0,03	deleterious	3,71	23,3	0,07	0,35	disease	0,86	disease	0,84	disease	0,75	disease	0,63	3	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-3,43	medium_impact	-0,29	high_impact	2,53	0,23	0,8	1,74	6,56	P	0,63	P	0,54	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8400	8400	T	C	MI.1517	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	35	12	M	T	aTa/aCa	3,14	0,03	0	benign	0	neutral	0,4	neutral	2,12	neutral	1,22	neutral	1,15	neutral_impact	-1,24	neutral	1	neutral	0,98	neutral	-1,89	0	0,47886177	0,85	neutral	0,11	neutral	0,08	neutral	0,49	neutral	0,04	9	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,12	high_impact	2,09	medium_impact	0,19	low_impact	-2,16	0,47	0,85	NA	NA	N	0,45	N	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10157	10157	A	C	MI.15170	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	99	33	K	N	aaA/aaC	8,69	1	0	probably_damaging	1	neutral	0,33	neutral	0,65	deleterious	-4,53	deleterious	-4,97	high_impact	4,32	damaging	0,55	damaging	0,04	deleterious	3,76	23,3	0,23	0,45	disease	0,69	disease	0,84	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,84	low_impact	-3,43	medium_impact	0,02	high_impact	2,85	0,38	0,8	1,74	6,56	P	0,64	P	0,71	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10157	10157	A	T	MI.15171	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	99	33	K	N	aaA/aaT	8,69	1	0	probably_damaging	1	neutral	0,33	neutral	0,65	deleterious	-4,53	deleterious	-4,97	high_impact	4,32	damaging	0,55	damaging	0,04	deleterious	3,84	23,4	0,23	0,45	disease	0,69	disease	0,84	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,84	low_impact	-3,43	medium_impact	0,02	high_impact	2,85	0,38	0,8	1,74	6,56	P	0,64	P	0,71	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10158	10158	T	C	MI.15172	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	100	34	S	P	Tcc/Ccc	1,05	0,4	0	possibly_damaging	0,47	neutral	0,34	neutral	0,88	neutral	-2,39	neutral	-2,09	low_impact	1,78	damaging	0,2	neutral	0,42	deleterious	2,25	17,84	0,1	0,4	neutral	0,5	disease	0,72	neutral	0,48	neutral	0,42	2	neutral	0,62	neutral	0,44	neutral	-3	neutral	0,4	medium_impact	-0,67	medium_impact	0,03	medium_impact	0,52	0,13	0,8	16,52	9,67	P	0,95	P	0,59	disease_causing_automatic	0	0,44	rs199476117	Pathogenic|Pathogenic|Pathogenic|Pathogenic	Leigh_syndrome_due_to_mitochondrial_complex_I_deficiency|Mitochondrial_complex_I_deficiency|Leigh_syndrome|not_provided	RCV000010360.2|RCV000010361.2|RCV000144009.2|RCV000224598.1	MedGen|MedGen:OMIM|MedGen:OMIM:Orphanet:SNOMED_CT|MedGen	MNGIE tissues	.	.	.	T10158C	Leigh Disease	+	+	Cfrm	13
chrM	10158	10158	T	A	MI.15173	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	100	34	S	T	Tcc/Acc	1,05	0,4	0	benign	0	neutral	0,45	neutral	0,92	neutral	-1,1	neutral	0,1	neutral_impact	0,71	neutral	0,85	neutral	0,99	deleterious	0,59	8,09	0,3	0,45	neutral	0,16	neutral	0,28	neutral	0,24	neutral	0,44	1	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,1	medium_impact	1,99	medium_impact	0,14	medium_impact	-0,46	0,34	0,8	16,52	9,67	N	0,37	N	0,02	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10158	10158	T	G	MI.15174	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	100	34	S	A	Tcc/Gcc	1,05	0,4	0	benign	0	neutral	0,57	neutral	0,95	neutral	-0,57	neutral	0,51	neutral_impact	0,01	neutral	0,86	neutral	0,98	neutral	-0,2	1,1	0,31	0,45	neutral	0,16	neutral	0,18	neutral	0,22	neutral	0,29	4	neutral	0,42	deleterious	0,79	neutral	-6	neutral	0,1	medium_impact	1,99	medium_impact	0,26	low_impact	-1,1	0,28	0,8	16,52	9,67	N	0,31	N	0,06	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10159	10159	C	T	MI.15175	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	101	34	S	F	tCc/tTc	-3,11	0	0	possibly_damaging	0,47	neutral	0,07	neutral	0,89	neutral	-1,88	neutral	-1,61	low_impact	1,86	damaging	0,52	neutral	0,58	deleterious	2,63	20,4	0,14	0,4	neutral	0,48	disease	0,53	neutral	0,43	neutral	0,43	1	neutral	0,92	neutral	0,3	neutral	-3	neutral	0,4	medium_impact	-0,67	medium_impact	-0,43	medium_impact	0,6	0,07	0,8	16,52	9,67	N	0,45	N	0,73	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10159	10159	C	G	MI.15176	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	101	34	S	C	tCc/tGc	-3,11	0	0	possibly_damaging	0,73	deleterious	0,04	neutral	0,86	deleterious	-3,46	neutral	-1,3	medium_impact	2,71	damaging	0,55	neutral	0,41	deleterious	3,24	22,8	0,12	0,4	disease	0,59	disease	0,54	neutral	0,47	neutral	0,41	2	neutral	0,97	neutral	0,16	deleterious	4	deleterious	0,49	low_impact	-1,11	medium_impact	-0,58	medium_impact	1,38	0,17	0,8	16,52	9,67	N	0,42	N	0,58	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10159	10159	C	A	MI.15177	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	101	34	S	Y	tCc/tAc	-3,11	0	0	possibly_damaging	0,66	neutral	0,1	neutral	0,89	neutral	-1,84	neutral	-1,44	low_impact	1,25	neutral	0,79	neutral	0,77	deleterious	2,45	19,17	0,1	0,4	disease	0,52	neutral	0,49	neutral	0,33	neutral	0,4	2	neutral	0,91	neutral	0,22	neutral	-3	deleterious	0,48	medium_impact	-0,98	medium_impact	-0,34	medium_impact	0,04	0,12	0,8	16,52	9,67	N	0,37	N	0,7	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10161	10161	A	C	MI.15178	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	103	35	T	P	Acc/Ccc	-7,04	0	0	benign	0,15	neutral	0,34	neutral	0,9	neutral	-2,29	neutral	-2,09	medium_impact	2,74	damaging	0,44	neutral	0,41	deleterious	2,03	16,41	0,04	0,35	neutral	0,43	disease	0,69	disease	0,58	disease	0,67	3	neutral	0,6	deleterious	0,6	neutral	-3	neutral	0,35	medium_impact	-0,04	medium_impact	0,03	medium_impact	1,4	0,32	0,8	12,17	11,96	N	0,47	N	0,32	polymorphism	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10161	10161	A	G	MI.15179	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	103	35	T	A	Acc/Gcc	-7,04	0	0	benign	0,02	neutral	0,88	neutral	0,97	neutral	-0,38	neutral	-0,86	low_impact	1,4	neutral	0,66	neutral	0,75	deleterious	1,99	16,14	0,2	0,45	neutral	0,18	neutral	0,29	disease	0,58	neutral	0,4	2	neutral	0,06	deleterious	0,93	neutral	-6	neutral	0,15	medium_impact	0,81	medium_impact	0,67	medium_impact	0,18	0,33	0,8	12,17	11,96	N	0,33	N	0,16	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8401	8401	A	C	MI.1518	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	36	12	M	I	atA/atC	-0,57	0	0	benign	0,01	neutral	1	neutral	2,55	neutral	3,02	neutral	0,04	neutral_impact	-1,57	neutral	1	neutral	0,9	neutral	-0,93	0,02	0,60038707	0,85	neutral	0,3	neutral	0,06	neutral	0,45	neutral	0,03	9	neutral	0,01	deleterious	1	neutral	-6	neutral	0,15	medium_impact	1,14	high_impact	1,98	low_impact	-2,44	0,61	0,85	NA	NA	N	0,44	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10161	10161	A	T	MI.15180	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	103	35	T	S	Acc/Tcc	-7,04	0	0	benign	0	neutral	0,83	neutral	1,14	neutral	1,18	neutral	1,8	neutral_impact	-1,28	neutral	0,88	neutral	0,94	neutral	-0,88	0,03	0,27	0,45	neutral	0,13	neutral	0,03	neutral	0,27	neutral	0,17	7	neutral	0,16	deleterious	0,92	neutral	-6	neutral	0,09	medium_impact	1,99	medium_impact	0,57	low_impact	-2,28	0,36	0,8	12,17	11,96	N	0,3	N	0,01	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10162	10162	C	G	MI.15181	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	104	35	T	S	aCc/aGc	2,21	0,02	0	benign	0	neutral	0,83	neutral	1,14	neutral	1,18	neutral	1,8	neutral_impact	-1,28	neutral	0,88	neutral	0,94	neutral	-1,17	0,01	0,27	0,45	neutral	0,13	neutral	0,03	neutral	0,27	neutral	0,17	7	neutral	0,16	deleterious	0,92	neutral	-6	neutral	0,09	medium_impact	1,99	medium_impact	0,57	low_impact	-2,28	0,36	0,8	12,17	11,96	N	0,31	N	0,01	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10162	10162	C	A	MI.15182	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	104	35	T	N	aCc/aAc	2,21	0,02	0	benign	0	neutral	0,57	neutral	0,94	neutral	-0,84	neutral	1,64	low_impact	0,84	neutral	0,93	neutral	0,97	deleterious	0,22	4,91	0,3	0,45	neutral	0,18	disease	0,55	neutral	0,38	neutral	0,15	7	neutral	0,43	deleterious	0,79	neutral	-6	neutral	0,17	medium_impact	1,99	medium_impact	0,26	medium_impact	-0,34	0,29	0,8	12,17	11,96	N	0,27	N	0,04	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10162	10162	C	T	MI.15183	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	104	35	T	I	aCc/aTc	2,21	0,02	0	benign	0,15	neutral	0,34	neutral	0,91	neutral	-1,81	deleterious	-3,06	low_impact	1,76	neutral	0,64	neutral	0,57	deleterious	2,06	16,57	0,12	0,4	neutral	0,44	neutral	0,46	disease	0,57	neutral	0,49	0	neutral	0,6	deleterious	0,6	neutral	-6	neutral	0,3	medium_impact	-0,04	medium_impact	0,03	medium_impact	0,51	0,46	0,8	12,17	11,96	N	0,43	N	0,42	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10164	10164	C	T	MI.15184	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	106	36	P	S	Cct/Tct	-3,8	0	0	probably_damaging	1	neutral	1	neutral	0,91	neutral	-0,77	deleterious	-7,36	medium_impact	2,82	neutral	0,63	damaging	0,09	deleterious	3,87	23,5	0,15	0,4	disease	0,75	disease	0,83	disease	0,65	disease	0,68	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,87	low_impact	-3,43	high_impact	1,85	medium_impact	1,48	0,09	0,8	NA	NA	N	0,21	N	0,95	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10164	10164	C	G	MI.15185	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	106	36	P	A	Cct/Gct	-3,8	0	0	probably_damaging	1	neutral	0,64	neutral	0,91	neutral	-0,72	deleterious	-7,32	medium_impact	2,04	damaging	0,6	damaging	0,1	deleterious	3,02	22,3	0,17	0,45	disease	0,72	disease	0,69	disease	0,66	disease	0,54	1	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	0,33	medium_impact	0,76	0,48	0,8	NA	NA	N	0,19	N	0,81	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10164	10164	C	A	MI.15186	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	106	36	P	T	Cct/Act	-3,8	0	0	probably_damaging	1	neutral	0,45	neutral	0,89	neutral	-0,97	deleterious	-7,46	medium_impact	2,76	damaging	0,58	damaging	0,06	deleterious	3,71	23,3	0,16	0,45	disease	0,8	disease	0,87	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,87	low_impact	-3,43	medium_impact	0,14	medium_impact	1,42	0,39	0,8	NA	NA	N	0,22	N	0,97	polymorphism	1	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10165	10165	C	G	MI.15187	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	107	36	P	R	cCt/cGt	3,6	0,99	0	probably_damaging	1	neutral	0,39	neutral	0,82	neutral	-2,23	deleterious	-8,47	high_impact	4,67	neutral	0,61	damaging	0,05	deleterious	3,59	23,2	0,08	0,35	disease	0,85	disease	0,88	disease	0,76	disease	0,64	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,9	low_impact	-3,43	medium_impact	0,08	high_impact	3,17	0,25	0,8	NA	NA	P	0,67	P	0,73	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10165	10165	C	T	MI.15188	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	107	36	P	L	cCt/cTt	3,6	0,99	0	probably_damaging	1	neutral	0,56	neutral	0,85	neutral	-1,57	deleterious	-9,43	high_impact	4,33	damaging	0,53	damaging	0,04	deleterious	4,28	24	0,1	0,4	disease	0,84	disease	0,86	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,87	low_impact	-3,43	medium_impact	0,25	high_impact	2,86	0,63	0,8	NA	NA	P	0,55	P	0,97	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10165	10165	C	A	MI.15189	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	107	36	P	H	cCt/cAt	3,6	0,99	0	probably_damaging	1	neutral	0,39	neutral	0,79	deleterious	-3,21	deleterious	-8,5	high_impact	4,67	damaging	0,54	damaging	0,04	deleterious	3,96	23,6	0,1	0,4	disease	0,92	disease	0,84	disease	0,74	disease	0,64	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,88	low_impact	-3,43	medium_impact	0,08	high_impact	3,17	0,22	0,8	NA	NA	P	0,61	P	0,74	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8401	8401	A	T	MI.1519	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	36	12	M	I	atA/atT	-0,57	0	0	benign	0,01	neutral	1	neutral	2,55	neutral	3,02	neutral	0,04	neutral_impact	-1,57	neutral	1	neutral	0,9	neutral	-0,88	0,03	0,60038707	0,85	neutral	0,3	neutral	0,06	neutral	0,45	neutral	0,03	9	neutral	0,01	deleterious	1	neutral	-6	neutral	0,15	medium_impact	1,14	high_impact	1,98	low_impact	-2,44	0,61	0,85	NA	NA	N	0,43	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10167	10167	T	A	MI.15190	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	109	37	Y	N	Tac/Aac	-14,68	0	0	probably_damaging	1	neutral	0,3	neutral	0,32	deleterious	-7,37	deleterious	-8,9	high_impact	4,62	damaging	0,56	damaging	0,04	deleterious	3,99	23,6	0,04	0,35	disease	0,77	disease	0,85	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	-0,01	high_impact	3,13	0,07	0,8	3,48	6,65	N	0,4	N	0,99	polymorphism	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10167	10167	T	C	MI.15191	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	109	37	Y	H	Tac/Cac	-14,68	0	0	probably_damaging	1	neutral	0,51	neutral	0,34	deleterious	-5,86	deleterious	-4,95	high_impact	4,07	damaging	0,57	damaging	0,03	deleterious	3,54	23,1	0,05	0,35	disease	0,61	disease	0,77	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-3,43	medium_impact	0,2	high_impact	2,62	0,14	0,8	3,48	6,65	N	0,27	N	0,98	polymorphism	1	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10167	10167	T	G	MI.15192	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	109	37	Y	D	Tac/Gac	-14,68	0	0	probably_damaging	1	neutral	0,21	neutral	0,32	deleterious	-8,49	deleterious	-9,89	high_impact	4,62	neutral	0,65	damaging	0,03	deleterious	3,96	23,6	0,03	0,35	disease	0,87	disease	0,85	disease	0,73	disease	0,64	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	-0,13	high_impact	3,13	0,06	0,8	3,48	6,65	N	0,42	N	0,97	disease_causing	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10168	10168	A	T	MI.15193	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	110	37	Y	F	tAc/tTc	7,53	1	0	probably_damaging	1	neutral	0,67	neutral	1,07	neutral	-2,77	deleterious	-3,94	low_impact	1,27	neutral	0,62	damaging	0,06	deleterious	3,33	22,9	0,14	0,4	neutral	0,16	disease	0,53	neutral	0,5	neutral	0,16	7	deleterious	1	neutral	0,34	neutral	-2	deleterious	0,74	low_impact	-3,43	medium_impact	0,36	medium_impact	0,06	0,27	0,8	3,48	6,65	N	0,46	N	0,81	polymorphism	1	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10168	10168	A	G	MI.15194	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	110	37	Y	C	tAc/tGc	7,53	1	0	probably_damaging	1	neutral	0,2	neutral	0,32	deleterious	-8,66	deleterious	-8,88	high_impact	4,62	damaging	0,58	damaging	0,04	deleterious	3,51	23,1	0,03	0,35	disease	0,88	disease	0,87	disease	0,76	disease	0,63	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,43	medium_impact	-0,14	high_impact	3,13	0,08	0,8	3,48	6,65	P	0,62	P	1	polymorphism	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10168	10168	A	C	MI.15195	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	110	37	Y	S	tAc/tCc	7,53	1	0	probably_damaging	1	neutral	0,5	neutral	0,32	deleterious	-7,12	deleterious	-8,89	high_impact	4,27	damaging	0,59	damaging	0,05	deleterious	3,68	23,3	0,04	0,35	disease	0,75	disease	0,85	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,87	low_impact	-3,43	medium_impact	0,19	high_impact	2,81	0,08	0,8	3,48	6,65	P	0,55	P	0,98	polymorphism	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10170	10170	G	C	MI.15196	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	112	38	E	Q	Gag/Cag	-2,42	0	0	probably_damaging	1	neutral	0,29	neutral	-0,53	deleterious	-6,23	deleterious	-2,98	high_impact	4,92	damaging	0,4	damaging	0,08	deleterious	3,35	22,9	0,09	0,35	disease	0,95	disease	0,73	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,43	medium_impact	-0,03	high_impact	3,4	0,42	0,8	1,74	6,81	P	0,69	P	0,9	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10170	10170	G	A	MI.15197	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	112	38	E	K	Gag/Aag	-2,42	0	0	probably_damaging	1	neutral	0,29	neutral	-0,51	deleterious	-5,62	deleterious	-3,97	high_impact	4,57	damaging	0,42	damaging	0,08	deleterious	4,46	24,2	0,05	0,35	disease	0,94	disease	0,85	disease	0,81	disease	0,66	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,91	low_impact	-3,43	medium_impact	-0,03	high_impact	3,08	0,44	0,8	1,74	6,81	P	0,63	P	0,99	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10171	10171	A	C	MI.15198	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	113	38	E	A	gAg/gCg	9,15	1	0	probably_damaging	1	neutral	0,5	neutral	-0,53	deleterious	-6,26	deleterious	-5,96	high_impact	4,92	damaging	0,48	damaging	0,11	deleterious	3,73	23,3	0,04	0,35	disease	0,94	disease	0,73	disease	0,77	disease	0,68	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,87	low_impact	-3,43	medium_impact	0,19	high_impact	3,4	0,28	0,8	1,74	6,81	P	0,74	P	0,76	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10171	10171	A	G	MI.15199	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	113	38	E	G	gAg/gGg	9,15	1	0	probably_damaging	1	neutral	0,33	neutral	-0,53	deleterious	-6,49	deleterious	-6,95	high_impact	4,92	damaging	0,39	damaging	0,11	deleterious	4,31	24	0,04	0,35	disease	0,93	disease	0,75	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,43	medium_impact	0,02	high_impact	3,4	0,12	0,8	1,74	6,81	P	0,82	P	0,61	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8597	8597	T	A	MI.152	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	71	24	I	N	aTt/aAt	0,36	0,01	0,01	probably_damaging	1	deleterious	0,01	neutral	3,88	deleterious	-5,67	deleterious	-5,61	medium_impact	2,66	neutral	0,87	neutral	0,51	deleterious	4,23	23,9	0,31	0,65	disease	0,79	disease	0,63	disease	0,59	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,18	0,61	0,9	18,14	17,22	N	0,41	N	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8402	8402	A	T	MI.1520	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	37	13	I	F	Att/Ttt	-6,12	0	0	probably_damaging	0,97	neutral	1	neutral	2,02	deleterious	-4,63	deleterious	-3,94	medium_impact	2,22	neutral	0,98	damaging	0,1	deleterious	3,51	23,1	0,28004023	0,85	disease	0,71	disease	0,51	disease	0,72	disease	0,65	3	neutral	0,97	deleterious	0,52	deleterious	1	deleterious	0,81	low_impact	-2,19	high_impact	1,98	medium_impact	0,81	0,63	0,85	11,76	7,19	N	0,26	N	0,93	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10171	10171	A	T	MI.15200	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	113	38	E	V	gAg/gTg	9,15	1	0	probably_damaging	1	neutral	0,49	neutral	-0,55	deleterious	-7,6	deleterious	-6,96	high_impact	4,92	damaging	0,38	damaging	0,07	deleterious	4,3	24	0,03	0,35	disease	0,97	disease	0,88	disease	0,8	disease	0,66	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,91	low_impact	-3,43	medium_impact	0,18	high_impact	3,4	0,2	0,8	1,74	6,81	P	0,8	P	0,84	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10172	10172	G	C	MI.15201	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	114	38	E	D	gaG/gaC	8,69	1	0,02	probably_damaging	1	neutral	0,2	neutral	-0,48	deleterious	-4,96	deleterious	-2,98	high_impact	4,57	damaging	0,52	damaging	0,09	deleterious	3,64	23,2	0,1	0,4	disease	0,87	disease	0,72	disease	0,72	disease	0,63	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,43	medium_impact	-0,14	high_impact	3,08	0,38	0,8	1,74	6,81	P	0,67	P	0,86	polymorphism	0,99	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10172	10172	G	T	MI.15202	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	114	38	E	D	gaG/gaT	8,69	1	0,02	probably_damaging	1	neutral	0,2	neutral	-0,48	deleterious	-4,96	deleterious	-2,98	high_impact	4,57	damaging	0,52	damaging	0,09	deleterious	3,8	23,4	0,1	0,4	disease	0,87	disease	0,72	disease	0,72	disease	0,63	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,43	medium_impact	-0,14	high_impact	3,08	0,38	0,8	1,74	6,81	P	0,67	P	0,86	polymorphism	0,99	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10173	10173	T	G	MI.15203	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	115	39	C	G	Tgc/Ggc	0,82	0,99	0	probably_damaging	1	neutral	0,38	neutral	0,36	deleterious	-3,61	deleterious	-11,67	high_impact	3,96	damaging	0,57	damaging	0,1	deleterious	3,32	22,9	0,05	0,35	disease	0,74	disease	0,86	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,88	low_impact	-3,43	medium_impact	0,07	high_impact	2,52	0,1	0,8	3,48	7,4	N	0,52	P	0,8	polymorphism	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10173	10173	T	A	MI.15204	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	115	39	C	S	Tgc/Agc	0,82	0,99	0	probably_damaging	1	neutral	0,49	neutral	0,64	neutral	-1,26	deleterious	-9,71	medium_impact	2,8	neutral	0,61	damaging	0,1	deleterious	3,7	23,3	0,05	0,35	disease	0,71	disease	0,86	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,87	low_impact	-3,43	medium_impact	0,18	medium_impact	1,46	0,15	0,8	3,48	7,4	N	0,4	N	0,51	polymorphism	1	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10173	10173	T	C	MI.15205	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	115	39	C	R	Tgc/Cgc	0,82	0,99	0	probably_damaging	1	neutral	0,41	neutral	0,33	deleterious	-5,72	deleterious	-11,68	high_impact	4,86	damaging	0,6	damaging	0,07	deleterious	3,55	23,1	0,04	0,35	disease	0,86	disease	0,9	disease	0,81	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,92	low_impact	-3,43	medium_impact	0,1	high_impact	3,35	0,05	0,8	3,48	7,4	P	0,61	P	0,88	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10174	10174	G	C	MI.15206	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	116	39	C	S	tGc/tCc	5,68	1	0	probably_damaging	1	neutral	0,49	neutral	0,64	neutral	-1,26	deleterious	-9,71	medium_impact	2,8	neutral	0,61	damaging	0,1	deleterious	3,14	22,6	0,05	0,35	disease	0,71	disease	0,86	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,87	low_impact	-3,43	medium_impact	0,18	medium_impact	1,46	0,15	0,8	3,48	7,4	N	0,51	P	0,51	polymorphism	1	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10174	10174	G	T	MI.15207	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	116	39	C	F	tGc/tTc	5,68	1	0	probably_damaging	1	neutral	0,71	neutral	0,33	deleterious	-6,25	deleterious	-10,69	high_impact	4,86	damaging	0,56	damaging	0,08	deleterious	3,91	23,5	0,04	0,35	disease	0,87	disease	0,91	disease	0,76	disease	0,62	2	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,91	low_impact	-3,43	medium_impact	0,41	high_impact	3,35	0,17	0,8	3,48	7,4	P	0,64	P	0,94	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10174	10174	G	A	MI.15208	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	116	39	C	Y	tGc/tAc	5,68	1	0	probably_damaging	1	neutral	1	neutral	0,33	deleterious	-6,66	deleterious	-10,69	high_impact	4,51	neutral	0,6	damaging	0,06	deleterious	3,56	23,1	0,05	0,35	disease	0,9	disease	0,9	disease	0,77	disease	0,61	2	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,91	low_impact	-3,43	high_impact	1,85	high_impact	3,03	0,19	0,8	3,48	7,4	P	0,62	P	0,93	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10175	10175	C	A	MI.15209	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	117	39	C	W	tgC/tgA	7,3	1	0	probably_damaging	1	neutral	0,19	neutral	0,31	deleterious	-8,29	deleterious	-10,68	high_impact	4,86	neutral	0,62	damaging	0,09	deleterious	4,54	24,3	0,04	0,35	disease	0,95	disease	0,88	disease	0,8	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,43	medium_impact	-0,16	high_impact	3,35	0,15	0,8	3,48	7,4	P	0,62	P	0,94	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8402	8402	A	C	MI.1521	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	37	13	I	L	Att/Ctt	-6,12	0	0	possibly_damaging	0,85	neutral	0,76	neutral	1,96	neutral	-2,5	neutral	-1,99	low_impact	1,82	neutral	0,98	damaging	0,1	deleterious	3,48	23,1	0,34020157	0,85	neutral	0,39	disease	0,52	disease	0,66	disease	0,63	3	neutral	0,83	neutral	0,46	neutral	-3	deleterious	0,59	low_impact	-1,47	medium_impact	0,57	medium_impact	0,46	0,66	0,85	11,76	7,19	N	0,3	N	0,68	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10175	10175	C	G	MI.15210	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	117	39	C	W	tgC/tgG	7,3	1	0	probably_damaging	1	neutral	0,19	neutral	0,31	deleterious	-8,29	deleterious	-10,68	high_impact	4,86	neutral	0,62	damaging	0,09	deleterious	4,26	23,9	0,04	0,35	disease	0,95	disease	0,88	disease	0,8	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,43	medium_impact	-0,16	high_impact	3,35	0,15	0,8	3,48	7,4	P	0,62	P	0,94	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10176	10176	G	C	MI.15211	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	118	40	G	R	Ggc/Cgc	-7,28	0	0	probably_damaging	1	neutral	0,35	neutral	-0,4	deleterious	-8,42	deleterious	-7,94	high_impact	4,92	damaging	0,57	damaging	0,06	deleterious	3,95	23,6	0,02	0,35	disease	0,98	disease	0,81	disease	0,84	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,91	low_impact	-3,43	medium_impact	0,04	high_impact	3,4	0,54	0,8	5,22	7,71	P	0,54	P	1	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10176	10176	G	A	MI.15212	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	118	40	G	S	Ggc/Agc	-7,28	0	0	probably_damaging	1	neutral	0,41	neutral	-0,34	deleterious	-6,53	deleterious	-5,96	high_impact	4,92	damaging	0,58	damaging	0,06	deleterious	4,14	23,8	0,03	0,35	disease	0,95	disease	0,79	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,88	low_impact	-3,43	medium_impact	0,1	high_impact	3,4	0,37	0,8	5,22	7,71	P	0,63	P	0,99	polymorphism	1	0,84	.	.	.	.	.	pancreatic cancer cell line	.	.	.	.	.	.	.	.	.
chrM	10176	10176	G	T	MI.15213	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	118	40	G	C	Ggc/Tgc	-7,28	0	0	probably_damaging	1	neutral	0,2	neutral	-0,4	deleterious	-8,96	deleterious	-8,94	high_impact	4,92	damaging	0,54	damaging	0,03	deleterious	4,19	23,8	0,03	0,35	disease	0,98	disease	0,83	disease	0,77	disease	0,66	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,43	medium_impact	-0,14	high_impact	3,4	0,17	0,8	5,22	7,71	N	0,46	N	0,99	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10177	10177	G	C	MI.15214	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	119	40	G	A	gGc/gCc	4,99	1	0	probably_damaging	1	neutral	0,51	neutral	-0,3	deleterious	-6,06	deleterious	-5,96	high_impact	4,92	neutral	0,62	damaging	0,09	deleterious	3,1	22,5	0,04	0,35	disease	0,94	disease	0,64	disease	0,76	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	0,2	high_impact	3,4	0,29	0,8	5,22	7,71	P	0,72	P	0,81	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10177	10177	G	T	MI.15215	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	119	40	G	V	gGc/gTc	4,99	1	0	probably_damaging	1	neutral	0,5	neutral	-0,39	deleterious	-7,92	deleterious	-8,94	high_impact	4,92	damaging	0,51	damaging	0,04	deleterious	3,76	23,3	0,03	0,35	disease	0,98	disease	0,84	disease	0,79	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,89	low_impact	-3,43	medium_impact	0,19	high_impact	3,4	0,15	0,8	5,22	7,71	P	0,6	P	0,98	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10177	10177	G	A	MI.15216	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	119	40	G	D	gGc/gAc	4,99	1	0	probably_damaging	1	neutral	0,21	neutral	-0,39	deleterious	-7,75	deleterious	-6,95	high_impact	4,92	damaging	0,59	damaging	0,04	deleterious	3,77	23,4	0,03	0,35	disease	0,97	disease	0,83	disease	0,83	disease	0,66	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-3,43	medium_impact	-0,13	high_impact	3,4	0,09	0,8	5,22	7,71	P	0,7	P	0,96	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10179	10179	T	C	MI.15217	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	121	41	F	L	Ttc/Ctc	-3,57	0	0	probably_damaging	1	neutral	0,65	neutral	0,75	neutral	-1,76	deleterious	-5,96	high_impact	3,62	damaging	0,56	damaging	0,09	deleterious	4,09	23,7	0,14	0,4	disease	0,5	disease	0,63	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,79	low_impact	-3,43	medium_impact	0,34	high_impact	2,21	0,43	0,8	2,61	7,05	N	0,34	N	0,91	polymorphism	1	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10179	10179	T	G	MI.15218	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	121	41	F	V	Ttc/Gtc	-3,57	0	0	probably_damaging	1	neutral	0,51	neutral	0,77	neutral	-1,54	deleterious	-6,95	medium_impact	3,06	damaging	0,57	damaging	0,09	deleterious	4,1	23,7	0,08	0,35	disease	0,68	disease	0,8	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,83	low_impact	-3,43	medium_impact	0,2	medium_impact	1,7	0,12	0,8	2,61	7,05	N	0,28	N	0,96	polymorphism	1	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10179	10179	T	A	MI.15219	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	121	41	F	I	Ttc/Atc	-3,57	0	0	probably_damaging	1	neutral	0,39	neutral	0,76	neutral	-1,71	deleterious	-5,96	medium_impact	2,81	neutral	0,61	damaging	0,12	deleterious	4,43	24,2	0,12	0,4	disease	0,67	disease	0,68	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	0,08	medium_impact	1,47	0,25	0,8	2,61	7,05	N	0,32	N	0,95	polymorphism	1	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8402	8402	A	G	MI.1522	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	37	13	I	V	Att/Gtt	-6,12	0	0	possibly_damaging	0,85	deleterious	0,03	neutral	1,8	neutral	-1,29	neutral	-0,99	medium_impact	2,71	neutral	0,99	neutral	0,57	deleterious	2,77	21,2	0,45672233	0,85	neutral	0,31	neutral	0,24	disease	0,69	neutral	0,24	5	deleterious	0,98	neutral	0,09	deleterious	4	deleterious	0,54	low_impact	-1,47	medium_impact	-0,56	medium_impact	1,23	0,7	0,85	11,76	7,19	P	0,58	P	0,39	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10180	10180	T	A	MI.15220	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	122	41	F	Y	tTc/tAc	5,68	1	0	probably_damaging	1	neutral	1	neutral	0,67	deleterious	-3,2	deleterious	-2,98	high_impact	4,08	neutral	0,61	damaging	0,1	deleterious	4,27	24	0,14	0,4	neutral	0,46	disease	0,66	disease	0,68	disease	0,65	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,78	low_impact	-3,43	high_impact	1,85	high_impact	2,63	0,42	0,8	2,61	7,05	P	0,57	P	0,89	polymorphism	1	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10180	10180	T	G	MI.15221	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	122	41	F	C	tTc/tGc	5,68	1	0	probably_damaging	1	neutral	0,22	neutral	0,65	deleterious	-4,27	deleterious	-7,95	high_impact	4,22	damaging	0,6	damaging	0,09	deleterious	4,11	23,7	0,05	0,35	disease	0,9	disease	0,76	disease	0,77	disease	0,66	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	-0,12	high_impact	2,76	0,1	0,8	2,61	7,05	P	0,72	P	0,99	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10180	10180	T	C	MI.15222	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	122	41	F	S	tTc/tCc	5,68	1	0	probably_damaging	1	neutral	0,41	neutral	0,7	neutral	-2,64	deleterious	-7,95	medium_impact	3,17	neutral	0,61	damaging	0,14	deleterious	4,25	23,9	0,03	0,35	disease	0,79	disease	0,81	disease	0,7	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,87	low_impact	-3,43	medium_impact	0,1	medium_impact	1,8	0,08	0,8	2,61	7,05	P	0,59	P	0,97	polymorphism	1	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10181	10181	C	A	MI.15223	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	123	41	F	L	ttC/ttA	7,53	1	0,04	probably_damaging	1	neutral	0,65	neutral	0,75	neutral	-1,76	deleterious	-5,96	high_impact	3,62	damaging	0,56	damaging	0,09	deleterious	4,62	24,5	0,14	0,4	disease	0,5	disease	0,63	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,79	low_impact	-3,43	medium_impact	0,34	high_impact	2,21	0,43	0,8	2,61	7,05	P	0,6	P	0,91	polymorphism	1	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10181	10181	C	G	MI.15224	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	123	41	F	L	ttC/ttG	7,53	1	0,04	probably_damaging	1	neutral	0,65	neutral	0,75	neutral	-1,76	deleterious	-5,96	high_impact	3,62	damaging	0,56	damaging	0,09	deleterious	4,34	24,1	0,14	0,4	disease	0,5	disease	0,63	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,79	low_impact	-3,43	medium_impact	0,34	high_impact	2,21	0,43	0,8	2,61	7,05	P	0,6	P	0,91	polymorphism	1	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10182	10182	G	C	MI.15225	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	124	42	D	H	Gac/Cac	-1,72	0	0	probably_damaging	0,97	neutral	0,54	neutral	0,82	neutral	-2,68	deleterious	-6,93	medium_impact	3,17	damaging	0,52	damaging	0,2	deleterious	3,49	23,1	0,08	0,35	disease	0,74	disease	0,8	disease	0,78	disease	0,69	4	neutral	0,97	neutral	0,29	deleterious	1	deleterious	0,85	low_impact	-2,08	medium_impact	0,23	medium_impact	1,8	0,19	0,8	4,35	7,15	N	0,35	N	0,99	polymorphism	1	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10182	10182	G	A	MI.15226	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	124	42	D	N	Gac/Aac	-1,72	0	0	probably_damaging	0,95	neutral	0,3	neutral	0,88	neutral	-1,17	deleterious	-4,96	medium_impact	2,14	damaging	0,44	neutral	0,36	deleterious	4,03	23,6	0,53	0,6	neutral	0,49	disease	0,77	disease	0,67	disease	0,55	1	neutral	0,96	neutral	0,18	deleterious	1	deleterious	0,81	low_impact	-1,87	medium_impact	-0,01	medium_impact	0,85	0,63	0,8	4,35	7,15	N	0,47	N	0,98	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10182	10182	G	T	MI.15227	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	124	42	D	Y	Gac/Tac	-1,72	0	0	benign	0,17	neutral	1	neutral	0,8	deleterious	-3,56	deleterious	-8,92	high_impact	4,01	damaging	0,52	damaging	0,23	deleterious	1,93	15,77	0,04	0,35	disease	0,85	disease	0,9	disease	0,77	disease	0,66	3	neutral	0,17	deleterious	0,92	neutral	-2	deleterious	0,46	medium_impact	-0,1	high_impact	1,85	high_impact	2,57	0,02	0,8	4,35	7,15	N	0,39	N	1	polymorphism	1	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10183	10183	A	T	MI.15228	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	125	42	D	V	gAc/gTc	6,14	1	0	probably_damaging	0,94	neutral	0,5	neutral	0,89	neutral	-1,13	deleterious	-8,92	medium_impact	3,27	damaging	0,47	damaging	0,27	deleterious	4,08	23,7	0,04	0,35	disease	0,79	disease	0,89	disease	0,75	disease	0,67	3	neutral	0,94	neutral	0,28	deleterious	1	deleterious	0,86	low_impact	-1,8	medium_impact	0,19	medium_impact	1,89	0,01	0,8	4,35	7,15	P	0,66	P	0,99	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10183	10183	A	C	MI.15229	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	125	42	D	A	gAc/gCc	6,14	1	0	probably_damaging	0,94	neutral	0,5	neutral	0,87	neutral	-1,31	deleterious	-7,93	high_impact	3,66	damaging	0,59	neutral	0,37	deleterious	3,9	23,5	0,07	0,35	disease	0,59	disease	0,79	disease	0,75	disease	0,69	4	neutral	0,93	neutral	0,28	deleterious	2	deleterious	0,8	low_impact	-1,8	medium_impact	0,19	high_impact	2,25	0,21	0,8	4,35	7,15	P	0,66	P	0,94	polymorphism	1	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8403	8403	T	G	MI.1523	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	38	13	I	S	aTt/aGt	-0,1	0	0	probably_damaging	0,97	neutral	0,12	neutral	1,73	deleterious	-4,61	deleterious	-5,98	medium_impact	3,26	neutral	0,97	damaging	0,09	deleterious	4,04	23,7	0,2329555	0,85	disease	0,78	disease	0,68	disease	0,73	disease	0,63	3	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,84	low_impact	-2,19	medium_impact	-0,2	medium_impact	1,7	0,51	0,85	11,76	7,19	N	0,43	N	0,9	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10183	10183	A	G	MI.15230	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	125	42	D	G	gAc/gGc	6,14	1	0	probably_damaging	0,95	neutral	0,34	neutral	0,82	neutral	-2,49	deleterious	-6,94	high_impact	3,75	damaging	0,52	neutral	0,37	deleterious	4,34	24	0,06	0,35	disease	0,6	disease	0,81	disease	0,76	disease	0,69	4	neutral	0,96	neutral	0,2	deleterious	2	deleterious	0,82	low_impact	-1,87	medium_impact	0,03	high_impact	2,33	0,16	0,8	4,35	7,15	P	0,67	P	0,98	polymorphism	1	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10184	10184	C	A	MI.15231	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	126	42	D	E	gaC/gaA	8,69	1	0	probably_damaging	0,92	neutral	0,28	neutral	0,95	neutral	-0,37	deleterious	-3,95	low_impact	1,88	damaging	0,51	neutral	0,33	deleterious	3,92	23,5	0,3	0,45	neutral	0,34	disease	0,67	disease	0,63	disease	0,54	1	neutral	0,94	neutral	0,18	neutral	-2	deleterious	0,74	low_impact	-1,68	medium_impact	-0,04	medium_impact	0,62	0,38	0,8	4,35	7,15	P	0,65	P	0,93	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10184	10184	C	G	MI.15232	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	126	42	D	E	gaC/gaG	8,69	1	0	probably_damaging	0,92	neutral	0,28	neutral	0,95	neutral	-0,37	deleterious	-3,95	low_impact	1,88	damaging	0,51	neutral	0,33	deleterious	3,6	23,2	0,3	0,45	neutral	0,34	disease	0,67	disease	0,63	disease	0,54	1	neutral	0,94	neutral	0,18	neutral	-2	deleterious	0,74	low_impact	-1,68	medium_impact	-0,04	medium_impact	0,62	0,38	0,8	4,35	7,15	P	0,65	P	0,93	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10185	10185	C	A	MI.15233	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	127	43	P	T	Cct/Act	-1,03	0	0	probably_damaging	1	neutral	0,39	neutral	0,83	neutral	-1,6	deleterious	-7,94	medium_impact	3,23	damaging	0,59	damaging	0,07	deleterious	3,82	23,4	0,13	0,4	disease	0,8	disease	0,77	disease	0,72	disease	0,66	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,84	low_impact	-3,43	medium_impact	0,08	medium_impact	1,85	0,46	0,8	2,61	6,75	N	0,27	N	0,97	polymorphism	1	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10185	10185	C	G	MI.15234	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	127	43	P	A	Cct/Gct	-1,03	0	0	probably_damaging	1	neutral	0,5	neutral	0,92	neutral	-1,08	deleterious	-7,94	medium_impact	2,83	neutral	0,62	damaging	0,11	deleterious	3,04	22,4	0,12	0,4	disease	0,72	disease	0,58	disease	0,71	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,79	low_impact	-3,43	medium_impact	0,19	medium_impact	1,49	0,58	0,8	2,61	6,75	N	0,28	N	0,81	polymorphism	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10185	10185	C	T	MI.15235	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	127	43	P	S	Cct/Tct	-1,03	0	0	probably_damaging	1	neutral	0,4	neutral	0,92	neutral	-1,52	deleterious	-7,94	medium_impact	2,4	neutral	0,63	damaging	0,09	deleterious	3,83	23,4	0,11	0,4	disease	0,75	disease	0,77	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,84	low_impact	-3,43	medium_impact	0,09	medium_impact	1,09	0,12	0,8	2,61	6,75	N	0,25	N	0,95	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10186	10186	C	T	MI.15236	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	128	43	P	L	cCt/cTt	4,52	0,98	0	probably_damaging	1	neutral	0,66	neutral	0,83	neutral	-1,94	deleterious	-9,93	medium_impact	3,47	damaging	0,57	damaging	0,07	deleterious	4,26	23,9	0,07	0,35	disease	0,84	disease	0,75	disease	0,7	disease	0,66	3	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,84	low_impact	-3,43	medium_impact	0,35	high_impact	2,07	0,52	0,8	2,61	6,75	N	0,5	N	0,97	polymorphism	1	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10186	10186	C	A	MI.15237	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	128	43	P	H	cCt/cAt	4,52	0,98	0	probably_damaging	1	neutral	0,54	neutral	0,78	deleterious	-3,36	deleterious	-8,93	high_impact	4,2	damaging	0,56	damaging	0,06	deleterious	3,92	23,5	0,07	0,35	disease	0,92	disease	0,77	disease	0,76	disease	0,67	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	0,23	high_impact	2,74	0,28	0,8	2,61	6,75	P	0,59	P	0,74	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10186	10186	C	G	MI.15238	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	128	43	P	R	cCt/cGt	4,52	0,98	0	probably_damaging	1	neutral	0,34	neutral	0,81	neutral	-2,41	deleterious	-8,93	high_impact	4,2	neutral	0,63	damaging	0,06	deleterious	3,58	23,2	0,06	0,35	disease	0,85	disease	0,8	disease	0,77	disease	0,68	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	0,03	high_impact	2,74	0,24	0,8	2,61	6,75	P	0,66	P	0,73	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10188	10188	A	C	MI.15239	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	130	44	M	L	Ata/Cta	-11,9	0	0	benign	0	neutral	0,68	neutral	1,13	neutral	1,03	neutral	-0,44	neutral_impact	-0,26	neutral	0,85	neutral	0,96	neutral	-1,27	0,01	0,21	0,45	neutral	0,1	neutral	0,12	neutral	0,29	neutral	0,24	5	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,08	medium_impact	1,99	medium_impact	0,37	low_impact	-1,35	0,12	0,8	21,74	12,32	N	0,38	N	0,04	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8403	8403	T	A	MI.1524	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	38	13	I	N	aTt/aAt	-0,1	0	0	probably_damaging	0,99	deleterious	0,03	neutral	1,71	deleterious	-5,72	deleterious	-6,97	high_impact	3,6	neutral	0,97	damaging	0,12	deleterious	4,3	24	0,20211531	0,85	disease	0,87	disease	0,7	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,88	low_impact	-2,65	medium_impact	-0,56	medium_impact	1,99	0,48	0,85	11,76	7,19	N	0,44	N	0,97	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10188	10188	A	T	MI.15240	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	130	44	M	L	Ata/Tta	-11,9	0	0	benign	0	neutral	0,68	neutral	1,13	neutral	1,03	neutral	-0,44	neutral_impact	-0,26	neutral	0,85	neutral	0,96	neutral	-1,13	0,01	0,21	0,45	neutral	0,1	neutral	0,12	neutral	0,29	neutral	0,24	5	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,08	medium_impact	1,99	medium_impact	0,37	low_impact	-1,35	0,12	0,8	21,74	12,32	N	0,37	N	0,04	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10188	10188	A	G	MI.15241	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	130	44	M	V	Ata/Gta	-11,9	0	0	benign	0	neutral	0,51	neutral	1,07	neutral	1,55	neutral	-1,6	low_impact	1,26	neutral	0,87	neutral	0,92	deleterious	0,87	9,87	0,24	0,45	neutral	0,17	neutral	0,48	neutral	0,44	neutral	0,33	3	neutral	0,49	deleterious	0,76	neutral	-6	neutral	0,12	medium_impact	1,99	medium_impact	0,2	medium_impact	0,05	0,18	0,8	21,74	12,32	N	0,37	N	0,27	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10189	10189	T	C	MI.15242	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	131	44	M	T	aTa/aCa	-0,1	0	0	benign	0,02	neutral	0,43	neutral	1,02	neutral	1,02	deleterious	-2,8	neutral_impact	0,8	neutral	0,84	neutral	0,91	neutral	-0,31	0,63	0,16	0,45	neutral	0,16	neutral	0,48	neutral	0,45	neutral	0,34	3	neutral	0,55	deleterious	0,71	neutral	-6	neutral	0,13	medium_impact	0,81	medium_impact	0,12	medium_impact	-0,38	0,1	0,8	21,74	12,32	N	0,31	N	0,08	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10189	10189	T	A	MI.15243	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	131	44	M	K	aTa/aAa	-0,1	0	0	benign	0,04	neutral	0,34	neutral	1,05	neutral	-0,77	deleterious	-4,18	low_impact	0,85	neutral	0,69	neutral	0,35	deleterious	2	16,21	0,1	0,4	neutral	0,12	disease	0,54	neutral	0,47	neutral	0,21	6	neutral	0,64	deleterious	0,65	neutral	-6	neutral	0,15	medium_impact	0,53	medium_impact	0,03	medium_impact	-0,33	0,15	0,8	21,74	12,32	N	0,33	N	0,68	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10190	10190	A	T	MI.15244	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	132	44	M	I	atA/atT	2,21	0,18	0	benign	0	neutral	0,41	neutral	1,05	neutral	1,05	neutral	-1,34	neutral_impact	0,53	neutral	0,84	neutral	0,87	deleterious	0,42	6,82	0,19	0,45	neutral	0,2	neutral	0,45	neutral	0,4	neutral	0,42	2	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,14	medium_impact	1,99	medium_impact	0,1	medium_impact	-0,62	0,17	0,8	21,74	12,32	N	0,34	N	0,25	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10190	10190	A	C	MI.15245	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	132	44	M	I	atA/atC	2,21	0,18	0	benign	0	neutral	0,41	neutral	1,05	neutral	1,05	neutral	-1,34	neutral_impact	0,53	neutral	0,84	neutral	0,87	deleterious	0,39	6,54	0,19	0,45	neutral	0,2	neutral	0,45	neutral	0,4	neutral	0,42	2	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,14	medium_impact	1,99	medium_impact	0,1	medium_impact	-0,62	0,17	0,8	21,74	12,32	N	0,33	N	0,25	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10191	10191	T	G	MI.15246	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	133	45	S	A	Tcc/Gcc	-0,1	0,15	0	benign	0,09	neutral	0,79	neutral	0,91	neutral	-0,27	neutral	-0,84	medium_impact	2,38	neutral	0,76	neutral	0,81	neutral	1,74	14,63	0,3	0,45	neutral	0,21	neutral	0,31	disease	0,56	neutral	0,4	2	neutral	0,11	deleterious	0,85	neutral	-3	neutral	0,15	medium_impact	0,19	medium_impact	0,51	medium_impact	1,07	0,35	0,8	25,22	17,51	N	0,35	N	0,1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10191	10191	T	A	MI.15247	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	133	45	S	T	Tcc/Acc	-0,1	0,15	0	benign	0,09	neutral	0,6	neutral	0,9	neutral	-0,75	neutral	-1,76	medium_impact	2,13	damaging	0,6	neutral	0,65	deleterious	1,82	15,08	0,33	0,5	neutral	0,25	neutral	0,35	disease	0,6	neutral	0,42	2	neutral	0,31	deleterious	0,76	neutral	-3	neutral	0,16	medium_impact	0,19	medium_impact	0,29	medium_impact	0,84	0,48	0,8	25,22	17,51	N	0,4	N	0,13	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10191	10191	T	C	MI.15248	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	133	45	S	P	Tcc/Ccc	-0,1	0,15	0	benign	0,43	neutral	0,3	neutral	0,85	neutral	-1,41	deleterious	-2,51	medium_impact	2,88	damaging	0,17	neutral	0,35	deleterious	2,31	18,21	0,12	0,4	neutral	0,44	disease	0,76	disease	0,6	disease	0,69	4	neutral	0,66	neutral	0,44	neutral	-3	deleterious	0,57	medium_impact	-0,61	medium_impact	-0,01	medium_impact	1,53	0,22	0,8	25,22	17,51	P	0,95	P	0,6	disease_causing_automatic	0	0,55	rs267606890	Pathogenic|Pathogenic	Mitochondrial_complex_I_deficiency|Leigh_syndrome	RCV000010358.2|RCV000144010.2	MedGen:OMIM|MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	T10191C	Leigh Disease/Leigh-like Disease/ESOC	-	+	Cfrm	18
chrM	10192	10192	C	G	MI.15249	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	134	45	S	C	tCc/tGc	3,6	1	0	possibly_damaging	0,71	neutral	0,08	neutral	0,82	deleterious	-4,12	deleterious	-3,36	medium_impact	3,23	neutral	0,69	neutral	0,43	deleterious	3,22	22,7	0,11	0,4	disease	0,63	disease	0,6	disease	0,54	disease	0,66	3	neutral	0,93	neutral	0,19	NA	0	deleterious	0,62	low_impact	-1,07	medium_impact	-0,4	medium_impact	1,85	0,27	0,8	25,22	17,51	P	0,6	P	0,56	polymorphism	1	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8403	8403	T	C	MI.1525	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	38	13	I	T	aTt/aCt	-0,1	0	0	probably_damaging	0,97	neutral	0,05	neutral	1,73	deleterious	-4,09	deleterious	-4,98	medium_impact	2,56	neutral	0,99	neutral	0,33	deleterious	3,23	22,8	0,34199561	0,85	disease	0,7	disease	0,58	disease	0,69	disease	0,64	3	deleterious	0,99	neutral	0,04	deleterious	1	deleterious	0,83	low_impact	-2,19	medium_impact	-0,43	medium_impact	1,1	0,55	0,85	11,76	7,19	P	0,62	P	0,9	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	T8403C	Episodic weakness and progressive neuropathy	+	-	Reported	1
chrM	10192	10192	C	A	MI.15250	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	134	45	S	Y	tCc/tAc	3,6	1	0	benign	0	neutral	0,17	neutral	0,84	neutral	-2,73	deleterious	-3,39	medium_impact	2,54	neutral	0,7	neutral	0,58	deleterious	2,2	17,48	0,09	0,35	neutral	0,43	disease	0,59	disease	0,64	disease	0,69	4	neutral	0,83	deleterious	0,59	neutral	-3	neutral	0,19	medium_impact	1,99	medium_impact	-0,19	medium_impact	1,22	0,2	0,8	25,22	17,51	N	0,53	P	0,06	polymorphism	1	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10192	10192	C	T	MI.15251	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	134	45	S	F	tCc/tTc	3,6	1	0	benign	0	neutral	0,14	neutral	0,84	deleterious	-3,14	deleterious	-3,55	medium_impact	2,6	neutral	0,62	neutral	0,54	deleterious	2,24	17,75	0,11	0,4	neutral	0,44	disease	0,65	disease	0,62	disease	0,7	4	neutral	0,86	deleterious	0,57	neutral	-3	neutral	0,21	medium_impact	1,99	medium_impact	-0,25	medium_impact	1,28	0,09	0,8	25,22	17,51	P	0,55	P	0,54	polymorphism	1	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10194	10194	C	T	MI.15252	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	136	46	P	S	Ccc/Tcc	-5,19	0	0	benign	0,26	neutral	0,94	neutral	1,12	neutral	1	neutral	3,12	neutral_impact	-2,06	neutral	0,79	neutral	0,93	neutral	1,18	11,66	0,27	0,45	neutral	0,14	neutral	0,13	neutral	0,19	neutral	0,25	5	neutral	0,18	deleterious	0,84	neutral	-6	neutral	0,24	medium_impact	-0,31	medium_impact	0,85	low_impact	-3	0,17	0,8	18,26	12,11	N	0,25	N	0,09	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10194	10194	C	G	MI.15253	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	136	46	P	A	Ccc/Gcc	-5,19	0	0	possibly_damaging	0,73	neutral	0,9	neutral	1,05	neutral	0,44	neutral	0,75	low_impact	1,02	neutral	0,75	neutral	0,71	deleterious	3,09	22,5	0,23	0,45	neutral	0,16	neutral	0,25	disease	0,52	neutral	0,38	2	neutral	0,69	deleterious	0,59	neutral	-3	deleterious	0,56	low_impact	-1,11	medium_impact	0,72	medium_impact	-0,17	0,56	0,8	18,26	12,11	N	0,3	N	0,48	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10194	10194	C	A	MI.15254	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	136	46	P	T	Ccc/Acc	-5,19	0	0	possibly_damaging	0,88	neutral	0,67	neutral	1,04	neutral	0,37	neutral	0,85	neutral_impact	0,38	neutral	0,8	neutral	0,8	deleterious	2,63	20,4	0,27	0,45	neutral	0,13	neutral	0,23	neutral	0,29	neutral	0,37	3	neutral	0,86	neutral	0,4	neutral	-3	deleterious	0,6	low_impact	-1,5	medium_impact	0,36	medium_impact	-0,76	0,46	0,8	18,26	12,11	N	0,26	N	0,56	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10195	10195	C	G	MI.15255	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	137	46	P	R	cCc/cGc	2,21	0,97	0	probably_damaging	0,97	neutral	0,63	neutral	1,04	neutral	0,12	neutral	-1,06	low_impact	1,57	neutral	0,75	neutral	0,45	deleterious	3,61	23,2	0,14	0,4	neutral	0,36	disease	0,67	disease	0,59	disease	0,66	3	neutral	0,97	neutral	0,33	neutral	-2	deleterious	0,74	low_impact	-2,08	medium_impact	0,32	medium_impact	0,33	0,31	0,8	18,26	12,11	N	0,37	N	0,76	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10195	10195	C	T	MI.15256	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	137	46	P	L	cCc/cTc	2,21	0,97	0	probably_damaging	0,94	neutral	0,79	neutral	1,03	neutral	-0,87	neutral	-1,76	low_impact	0,84	neutral	0,75	neutral	0,53	deleterious	4,4	24,1	0,16	0,45	neutral	0,36	neutral	0,4	disease	0,51	neutral	0,42	2	neutral	0,92	neutral	0,43	neutral	-2	deleterious	0,69	low_impact	-1,8	medium_impact	0,51	medium_impact	-0,34	0,56	0,8	18,26	12,11	N	0,39	N	0,89	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10195	10195	C	A	MI.15257	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	137	46	P	H	cCc/cAc	2,21	0,97	0	probably_damaging	0,99	neutral	0,58	neutral	0,99	neutral	-0,88	neutral	-1,08	neutral_impact	0,47	neutral	0,73	neutral	0,45	deleterious	4	23,6	0,17	0,45	disease	0,51	neutral	0,35	disease	0,52	neutral	0,45	1	deleterious	0,99	neutral	0,3	neutral	-2	deleterious	0,71	low_impact	-2,52	medium_impact	0,27	medium_impact	-0,68	0,26	0,8	18,26	12,11	N	0,42	N	0,77	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10197	10197	G	T	MI.15258	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	139	47	A	S	Gcc/Tcc	-20	0	0	probably_damaging	1	neutral	1	neutral	0,98	neutral	-1,42	deleterious	-2,76	low_impact	1,77	damaging	0,46	neutral	0,37	deleterious	3,72	23,3	0,26	0,45	neutral	0,17	disease	0,69	disease	0,71	neutral	0,36	3	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,75	low_impact	-3,43	high_impact	1,85	medium_impact	0,51	0,21	0,8	2,61	7,01	N	0,39	N	0,98	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10197	10197	G	A	MI.15259	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	139	47	A	T	Gcc/Acc	-20	0	0	probably_damaging	1	neutral	0,52	neutral	0,89	neutral	-1,8	deleterious	-3,52	medium_impact	2,54	damaging	0,09	neutral	0,38	deleterious	4,2	23,9	0,17	0,45	neutral	0,31	disease	0,74	disease	0,74	disease	0,58	2	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,79	low_impact	-3,43	medium_impact	0,21	medium_impact	1,22	0,76	0,85	2,61	7,01	P	0,88	P	0,93	disease_causing_automatic	0	0,53	rs267606891	Pathogenic|Pathogenic|Pathogenic	Leigh_syndrome_due_to_mitochondrial_complex_I_deficiency|Leber_hereditary_optic_neuropathy_with_dystonia|Leigh_syndrome	RCV000010362.2|RCV000010363.4|RCV000144011.2	MedGen|MedGen:OMIM|MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	G10197A	Leigh Disease/Dystonia/Stroke/LDYT	+	+	Cfrm	8
chrM	8404	8404	T	G	MI.1526	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	39	13	I	M	atT/atG	7,53	0,96	0	probably_damaging	0,99	neutral	0,26	neutral	1,8	deleterious	-4,37	deleterious	-2,99	low_impact	1,74	neutral	0,98	damaging	0,1	deleterious	3,22	22,7	0,34561211	0,85	disease	0,68	neutral	0,46	disease	0,7	neutral	0,45	1	deleterious	0,99	neutral	0,14	neutral	-2	deleterious	0,82	low_impact	-2,65	medium_impact	0,04	medium_impact	0,39	0,68	0,85	11,76	7,19	P	0,59	P	0,73	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10197	10197	G	C	MI.15260	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	139	47	A	P	Gcc/Ccc	-20	0	0	probably_damaging	1	neutral	0,32	neutral	0,82	deleterious	-3,08	deleterious	-4,73	medium_impact	2,73	damaging	0,39	damaging	0,24	deleterious	3,87	23,5	0,04	0,35	disease	0,58	disease	0,77	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,84	low_impact	-3,43	medium_impact	0,01	medium_impact	1,39	0,31	0,8	2,61	7,01	N	0,46	N	0,96	polymorphism	1	0,54	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	10198	10198	C	G	MI.15261	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	140	47	A	G	gCc/gGc	4,99	1	0	probably_damaging	1	neutral	0,45	neutral	0,85	neutral	-2,6	deleterious	-3,84	medium_impact	3,02	damaging	0,43	neutral	0,42	deleterious	4,02	23,6	0,24	0,45	neutral	0,44	disease	0,68	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-3,43	medium_impact	0,14	medium_impact	1,66	0,6	0,8	2,61	7,01	P	0,81	P	0,85	polymorphism	1	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10198	10198	C	A	MI.15262	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	140	47	A	D	gCc/gAc	4,99	1	0	probably_damaging	1	neutral	0,44	neutral	0,85	neutral	-2,63	deleterious	-5,67	high_impact	4,21	damaging	0,48	damaging	0,27	deleterious	4,52	24,3	0,04	0,35	disease	0,54	disease	0,84	disease	0,8	disease	0,71	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,8	low_impact	-3,43	medium_impact	0,13	high_impact	2,75	0,15	0,8	2,61	7,01	P	0,72	P	0,96	polymorphism	1	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10198	10198	C	T	MI.15263	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	140	47	A	V	gCc/gTc	4,99	1	0	probably_damaging	1	neutral	0,42	neutral	0,91	neutral	-2,51	deleterious	-3,75	medium_impact	3,46	damaging	0,38	neutral	0,31	deleterious	4,5	24,3	0,11	0,4	neutral	0,39	disease	0,79	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,78	low_impact	-3,43	medium_impact	0,11	high_impact	2,06	0,72	0,85	2,61	7,01	P	0,8	P	0,79	polymorphism	1	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10200	10200	C	T	MI.15264	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	142	48	R	C	Cgc/Tgc	-12,6	0	0	probably_damaging	1	neutral	0,18	neutral	0,72	deleterious	-5,07	deleterious	-7,66	high_impact	4,82	damaging	0,57	damaging	0,04	deleterious	5,02	25,2	0,08	0,35	disease	0,92	disease	0,8	disease	0,82	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,43	medium_impact	-0,18	high_impact	3,31	0,87	0,9	3,48	7,82	P	0,58	P	1	polymorphism	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10200	10200	C	G	MI.15265	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	142	48	R	G	Cgc/Ggc	-12,6	0	0	probably_damaging	1	neutral	0,33	neutral	0,77	neutral	-2,15	deleterious	-6,71	medium_impact	3,46	damaging	0,58	damaging	0,07	deleterious	4,23	23,9	0,07	0,35	disease	0,76	disease	0,68	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,8	low_impact	-3,43	medium_impact	0,02	high_impact	2,06	0,16	0,8	3,48	7,82	N	0,31	N	0,97	polymorphism	1	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10200	10200	C	A	MI.15266	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	142	48	R	S	Cgc/Agc	-12,6	0	0	probably_damaging	1	neutral	0,48	neutral	0,83	neutral	-1,68	deleterious	-5,72	medium_impact	3,46	neutral	0,62	damaging	0,06	deleterious	4,6	24,4	0,07	0,35	disease	0,72	disease	0,75	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,81	low_impact	-3,43	medium_impact	0,17	high_impact	2,06	0,22	0,8	3,48	7,82	N	0,3	N	0,81	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10201	10201	G	C	MI.15267	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	143	48	R	P	cGc/cCc	1,75	0,9	0	probably_damaging	1	neutral	0,28	neutral	0,74	deleterious	-3,4	deleterious	-6,71	high_impact	4,12	damaging	0,55	damaging	0,05	deleterious	4,27	24	0,04	0,35	disease	0,83	disease	0,77	disease	0,79	disease	0,67	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-3,43	medium_impact	-0,04	high_impact	2,67	0,1	0,8	3,48	7,82	N	0,47	N	0,99	polymorphism	1	0,65	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10201	10201	G	T	MI.15268	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	143	48	R	L	cGc/cTc	1,75	0,9	0	probably_damaging	1	neutral	0,67	neutral	0,76	neutral	-2,43	deleterious	-6,74	high_impact	4,12	damaging	0,59	damaging	0,04	deleterious	4,34	24	0,06	0,35	disease	0,76	disease	0,81	disease	0,79	disease	0,68	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,83	low_impact	-3,43	medium_impact	0,36	high_impact	2,67	0,06	0,8	3,48	7,82	N	0,45	N	1	polymorphism	1	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10201	10201	G	A	MI.15269	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	143	48	R	H	cGc/cAc	1,75	0,9	0	probably_damaging	1	neutral	0,54	neutral	0,75	neutral	-2,85	deleterious	-4,51	medium_impact	3,32	neutral	0,62	damaging	0,04	deleterious	4,36	24,1	0,2	0,45	disease	0,81	disease	0,71	disease	0,73	disease	0,59	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	0,23	medium_impact	1,94	0,94	0,95	3,48	7,82	N	0,35	N	1	polymorphism	1	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8404	8404	T	A	MI.1527	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	39	13	I	M	atT/atA	7,53	0,96	0	probably_damaging	0,99	neutral	0,26	neutral	1,8	deleterious	-4,37	deleterious	-2,99	low_impact	1,74	neutral	0,98	damaging	0,1	deleterious	3,52	23,1	0,34561211	0,85	disease	0,68	neutral	0,46	disease	0,7	neutral	0,45	1	deleterious	0,99	neutral	0,14	neutral	-2	deleterious	0,82	low_impact	-2,65	medium_impact	0,04	medium_impact	0,39	0,68	0,85	11,76	7,19	P	0,59	P	0,73	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10203	10203	G	A	MI.15270	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	145	49	V	I	Gtc/Atc	-8,43	0	0	benign	0,01	neutral	0,4	neutral	1	neutral	-0,16	neutral	0,94	neutral_impact	-0,95	neutral	0,79	neutral	0,73	deleterious	0,54	7,72	0,43	0,55	neutral	0,12	neutral	0,19	neutral	0,26	neutral	0,34	3	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,12	medium_impact	1,09	medium_impact	0,09	low_impact	-1,98	0,78	0,85	18,26	13,84	N	0,32	N	0,08	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10203	10203	G	C	MI.15271	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	145	49	V	L	Gtc/Ctc	-8,43	0	0	benign	0,05	neutral	0,68	neutral	1,02	neutral	0,01	neutral	2,44	neutral_impact	-2,12	neutral	0,73	neutral	0,95	neutral	-1,06	0,01	0,24	0,45	neutral	0,11	neutral	0,1	neutral	0,16	neutral	0,25	5	neutral	0,25	deleterious	0,82	neutral	-6	neutral	0,1	medium_impact	0,44	medium_impact	0,37	low_impact	-3,05	0,68	0,85	18,26	13,84	N	0,35	N	0,03	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10203	10203	G	T	MI.15272	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	145	49	V	F	Gtc/Ttc	-8,43	0	0	possibly_damaging	0,5	neutral	0,73	neutral	0,92	neutral	-1,44	neutral	-1,23	low_impact	0,86	neutral	0,71	neutral	0,62	deleterious	2,12	16,95	0,06	0,35	neutral	0,4	disease	0,61	disease	0,62	disease	0,65	3	neutral	0,4	deleterious	0,62	neutral	-3	neutral	0,37	medium_impact	-0,72	medium_impact	0,43	medium_impact	-0,32	0,36	0,8	18,26	13,84	N	0,27	N	0,41	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10204	10204	T	G	MI.15273	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	146	49	V	G	gTc/gGc	-0,1	0	0	possibly_damaging	0,72	neutral	0,34	neutral	1	neutral	-0,78	deleterious	-5,08	neutral_impact	0,4	neutral	0,62	neutral	0,46	deleterious	2,25	17,81	0,05	0,35	disease	0,71	neutral	0,47	disease	0,62	disease	0,66	3	neutral	0,77	neutral	0,31	neutral	-3	deleterious	0,53	low_impact	-1,09	medium_impact	0,03	medium_impact	-0,74	0,13	0,8	18,26	13,84	N	0,3	N	0,66	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10204	10204	T	A	MI.15274	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	146	49	V	D	gTc/gAc	-0,1	0	0	possibly_damaging	0,81	neutral	0,21	neutral	0,92	neutral	-2,1	deleterious	-4,99	low_impact	1,41	damaging	0,57	neutral	0,45	deleterious	4,14	23,8	0,03	0,35	disease	0,79	disease	0,66	disease	0,67	disease	0,67	3	neutral	0,88	neutral	0,2	neutral	-3	deleterious	0,67	low_impact	-1,29	medium_impact	-0,13	medium_impact	0,18	0,04	0,8	18,26	13,84	N	0,3	N	0,69	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10204	10204	T	C	MI.15275	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	146	49	V	A	gTc/gCc	-0,1	0	0	benign	0,26	neutral	0,53	neutral	0,98	neutral	-0,51	neutral	-2,16	neutral_impact	0,56	damaging	0,6	neutral	0,68	neutral	1,72	14,51	0,17	0,45	neutral	0,4	neutral	0,27	disease	0,58	neutral	0,45	1	neutral	0,37	deleterious	0,64	neutral	-6	neutral	0,27	medium_impact	-0,31	medium_impact	0,22	medium_impact	-0,6	0,16	0,8	18,26	13,84	N	0,34	N	0,32	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10206	10206	C	G	MI.15276	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	148	50	P	A	Cct/Gct	-12,37	0	0	probably_damaging	1	neutral	0,54	neutral	0,94	neutral	0,39	deleterious	-7,76	medium_impact	3,14	damaging	0,56	damaging	0,06	deleterious	3,08	22,5	0,2	0,45	disease	0,72	disease	0,65	disease	0,72	disease	0,66	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,79	low_impact	-3,43	medium_impact	0,23	medium_impact	1,77	0,58	0,8	3,48	6,69	N	0,26	N	0,81	polymorphism	1	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10206	10206	C	A	MI.15277	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	148	50	P	T	Cct/Act	-12,37	0	0	probably_damaging	1	neutral	0,42	neutral	0,91	neutral	0,21	deleterious	-7,76	medium_impact	3,35	damaging	0,55	damaging	0,03	deleterious	3,71	23,3	0,17	0,45	disease	0,8	disease	0,78	disease	0,7	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,85	low_impact	-3,43	medium_impact	0,11	medium_impact	1,96	0,53	0,8	3,48	6,69	N	0,29	N	0,97	polymorphism	1	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10206	10206	C	T	MI.15278	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	148	50	P	S	Cct/Tct	-12,37	0	0	probably_damaging	1	neutral	0,46	neutral	0,94	neutral	0,47	deleterious	-7,76	medium_impact	3,02	damaging	0,57	damaging	0,04	deleterious	3,92	23,5	0,24	0,45	disease	0,75	disease	0,81	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,83	low_impact	-3,43	medium_impact	0,15	medium_impact	1,66	0,11	0,8	3,48	6,69	N	0,27	N	0,95	polymorphism	1	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10207	10207	C	G	MI.15279	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	149	50	P	R	cCt/cGt	7,3	1	0	probably_damaging	1	neutral	0,4	neutral	0,95	neutral	1,75	deleterious	-8,74	medium_impact	2,43	neutral	0,67	damaging	0,03	deleterious	3,65	23,2	0,09	0,35	disease	0,85	disease	0,89	disease	0,76	disease	0,63	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,87	low_impact	-3,43	medium_impact	0,09	medium_impact	1,12	0,29	0,8	3,48	6,69	P	0,54	P	0,73	polymorphism	1	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8405	8405	A	C	MI.1528	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	40	14	T	P	Acc/Ccc	-2,65	0	0	benign	0,14	neutral	0,05	neutral	1,92	neutral	-2,97	deleterious	-2,6	medium_impact	2,2	neutral	0,99	neutral	0,4	neutral	1,34	12,48	0,22335685	0,85	disease	0,61	disease	0,58	disease	0,67	disease	0,66	3	neutral	0,94	neutral	0,46	neutral	-3	neutral	0,32	medium_impact	-0,01	medium_impact	-0,43	medium_impact	0,79	0,57	0,85	NA	NA	N	0,46	N	0,58	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10207	10207	C	T	MI.15280	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	149	50	P	L	cCt/cTt	7,3	1	0	probably_damaging	1	neutral	0,7	neutral	0,9	neutral	-0,54	deleterious	-9,72	high_impact	4,12	damaging	0,54	damaging	0,02	deleterious	4,35	24,1	0,12	0,4	disease	0,84	disease	0,82	disease	0,7	disease	0,64	3	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,84	low_impact	-3,43	medium_impact	0,39	high_impact	2,67	0,75	0,85	3,48	6,69	P	0,58	P	0,97	polymorphism	1	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10207	10207	C	A	MI.15281	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	149	50	P	H	cCt/cAt	7,3	1	0	probably_damaging	1	neutral	0,55	neutral	0,88	neutral	-1,02	deleterious	-8,74	high_impact	4,32	damaging	0,59	damaging	0,02	deleterious	4,02	23,6	0,12	0,4	disease	0,92	disease	0,84	disease	0,76	disease	0,62	2	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	0,24	high_impact	2,85	0,23	0,8	3,48	6,69	P	0,62	P	0,74	polymorphism	1	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10209	10209	T	A	MI.15282	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	151	51	F	I	Ttc/Atc	-10,98	0	0	probably_damaging	1	neutral	0,35	neutral	0,61	neutral	-2,88	deleterious	-5,82	medium_impact	3,29	neutral	0,75	damaging	0,12	deleterious	4,42	24,2	0,06	0,35	disease	0,67	disease	0,83	disease	0,73	neutral	0,4	2	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,84	low_impact	-3,43	medium_impact	0,04	medium_impact	1,91	0,3	0,8	NA	NA	N	0,36	N	0,95	polymorphism	1	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10209	10209	T	G	MI.15283	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	151	51	F	V	Ttc/Gtc	-10,98	0	0	probably_damaging	1	neutral	0,48	neutral	0,65	neutral	-2,84	deleterious	-6,8	high_impact	3,61	neutral	0,7	damaging	0,08	deleterious	4,17	23,8	0,05	0,35	disease	0,68	disease	0,88	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,84	low_impact	-3,43	medium_impact	0,17	high_impact	2,2	0,27	0,8	NA	NA	N	0,36	N	0,96	polymorphism	1	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10209	10209	T	C	MI.15284	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	151	51	F	L	Ttc/Ctc	-10,98	0	0	probably_damaging	1	neutral	0,59	neutral	0,64	neutral	-2,2	deleterious	-5,82	medium_impact	3,44	neutral	0,79	damaging	0,11	deleterious	4,05	23,7	0,05	0,35	disease	0,5	disease	0,73	disease	0,72	disease	0,57	1	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,79	low_impact	-3,43	medium_impact	0,28	high_impact	2,05	0,61	0,8	NA	NA	N	0,3	N	0,91	polymorphism	1	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10210	10210	T	C	MI.15285	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	152	51	F	S	tTc/tCc	3,83	1	0	probably_damaging	1	neutral	0,84	neutral	0,49	deleterious	-4,08	deleterious	-7,76	high_impact	4,16	neutral	0,73	damaging	0,08	deleterious	4,24	23,9	0,02	0,35	disease	0,79	disease	0,86	disease	0,76	disease	0,68	4	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,87	low_impact	-3,43	medium_impact	0,59	high_impact	2,71	0,08	0,8	NA	NA	P	0,57	P	0,97	polymorphism	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10210	10210	T	A	MI.15286	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	152	51	F	Y	tTc/tAc	3,83	1	0	probably_damaging	1	neutral	0,49	neutral	0,51	neutral	-2,71	deleterious	-2,92	medium_impact	2,95	neutral	0,74	neutral	0,36	deleterious	4,21	23,9	0,09	0,35	neutral	0,46	disease	0,7	disease	0,61	neutral	0,32	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,79	low_impact	-3,43	medium_impact	0,18	medium_impact	1,6	0,58	0,8	NA	NA	P	0,57	P	0,89	polymorphism	1	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10210	10210	T	G	MI.15287	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	152	51	F	C	tTc/tGc	3,83	1	0	probably_damaging	1	neutral	0,13	neutral	0,47	deleterious	-5,5	deleterious	-7,78	high_impact	4,5	neutral	0,7	damaging	0,08	deleterious	4,11	23,8	0,02	0,35	disease	0,9	disease	0,85	disease	0,8	disease	0,67	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	-0,27	high_impact	3,02	0,11	0,8	NA	NA	P	0,64	P	0,99	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10211	10211	C	A	MI.15288	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	153	51	F	L	ttC/ttA	7,53	1	0,02	probably_damaging	1	neutral	0,59	neutral	0,64	neutral	-2,2	deleterious	-5,82	medium_impact	3,44	neutral	0,79	damaging	0,11	deleterious	4,6	24,4	0,05	0,35	disease	0,5	disease	0,73	disease	0,72	disease	0,57	1	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,79	low_impact	-3,43	medium_impact	0,28	high_impact	2,05	0,61	0,8	NA	NA	P	0,54	P	0,91	polymorphism	1	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10211	10211	C	G	MI.15289	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	153	51	F	L	ttC/ttG	7,53	1	0,02	probably_damaging	1	neutral	0,59	neutral	0,64	neutral	-2,2	deleterious	-5,82	medium_impact	3,44	neutral	0,79	damaging	0,11	deleterious	4,36	24,1	0,05	0,35	disease	0,5	disease	0,73	disease	0,72	disease	0,57	1	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,79	low_impact	-3,43	medium_impact	0,28	high_impact	2,05	0,61	0,8	NA	NA	P	0,54	P	0,91	polymorphism	1	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8405	8405	A	T	MI.1529	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	40	14	T	S	Acc/Tcc	-2,65	0	0	benign	0,03	neutral	0,17	neutral	1,99	neutral	-0,27	neutral	-1,33	low_impact	1,16	neutral	1	neutral	0,87	neutral	1,12	11,33	0,53760445	0,85	neutral	0,39	neutral	0,17	neutral	0,36	neutral	0,12	8	neutral	0,82	deleterious	0,57	neutral	-6	neutral	0,14	medium_impact	0,68	medium_impact	-0,1	medium_impact	-0,1	0,75	0,85	NA	NA	P	0,57	P	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10212	10212	T	G	MI.15290	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	154	52	S	A	Tcc/Gcc	-1,03	0,02	0	probably_damaging	1	neutral	0,79	neutral	0,76	neutral	-1,98	deleterious	-2,9	high_impact	4,21	damaging	0,55	damaging	0,12	deleterious	3,64	23,2	0,16	0,45	neutral	0,44	disease	0,55	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,4	deleterious	2	deleterious	0,75	low_impact	-3,43	medium_impact	0,51	high_impact	2,75	0,33	0,8	2,61	6,64	N	0,33	N	0,5	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10212	10212	T	A	MI.15291	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	154	52	S	T	Tcc/Acc	-1,03	0,02	0	probably_damaging	1	neutral	0,6	neutral	0,79	neutral	-1,59	deleterious	-2,9	high_impact	3,6	damaging	0,51	damaging	0,13	deleterious	3,73	23,3	0,19	0,45	disease	0,56	disease	0,64	disease	0,7	disease	0,65	3	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,81	low_impact	-3,43	medium_impact	0,29	high_impact	2,19	0,52	0,8	2,61	6,64	N	0,32	N	0,72	polymorphism	1	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10212	10212	T	C	MI.15292	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	154	52	S	P	Tcc/Ccc	-1,03	0,02	0	probably_damaging	1	neutral	0,34	neutral	0,72	neutral	-2,77	deleterious	-4,83	medium_impact	3,07	damaging	0,44	damaging	0,07	deleterious	3,94	23,5	0,05	0,35	disease	0,74	disease	0,78	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,86	low_impact	-3,43	medium_impact	0,03	medium_impact	1,71	0,17	0,8	2,61	6,64	N	0,41	N	0,98	polymorphism	1	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10213	10213	C	T	MI.15293	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	155	52	S	F	tCc/tTc	5,68	1	0	probably_damaging	1	neutral	0,23	neutral	0,69	deleterious	-4,6	deleterious	-5,83	high_impact	4,41	damaging	0,43	damaging	0,04	deleterious	4,29	24	0,05	0,35	disease	0,83	disease	0,85	disease	0,72	disease	0,65	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-3,43	medium_impact	-0,1	high_impact	2,94	0,07	0,8	2,61	6,64	P	0,7	P	1	polymorphism	1	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10213	10213	C	A	MI.15294	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	155	52	S	Y	tCc/tAc	5,68	1	0	probably_damaging	1	neutral	0,16	neutral	0,69	deleterious	-4,22	deleterious	-5,83	high_impact	4,41	damaging	0,52	damaging	0,06	deleterious	4,11	23,7	0,05	0,35	disease	0,85	disease	0,83	disease	0,72	disease	0,62	2	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	-0,21	high_impact	2,94	0,19	0,8	2,61	6,64	P	0,65	P	1	polymorphism	1	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10213	10213	C	G	MI.15295	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	155	52	S	C	tCc/tGc	5,68	1	0	probably_damaging	1	neutral	0,07	neutral	0,69	deleterious	-4,75	deleterious	-4,87	high_impact	3,95	damaging	0,5	damaging	0,06	deleterious	3,58	23,2	0,06	0,35	disease	0,81	disease	0,75	disease	0,69	disease	0,64	3	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,82	low_impact	-3,43	medium_impact	-0,43	high_impact	2,51	0,26	0,8	2,61	6,64	P	0,62	P	1	polymorphism	1	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10215	10215	A	G	MI.15296	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	157	53	M	V	Ata/Gta	-8,66	0	0	probably_damaging	0,98	neutral	0,51	neutral	1,18	neutral	1,67	deleterious	-3,55	low_impact	0,86	neutral	0,91	neutral	0,66	deleterious	2,76	21,2	0,27	0,45	neutral	0,24	disease	0,71	disease	0,65	neutral	0,4	2	deleterious	0,98	neutral	0,27	neutral	-2	deleterious	0,66	low_impact	-2,24	medium_impact	0,2	medium_impact	-0,32	0,36	0,8	0,87	7,08	N	0,34	N	0,96	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10215	10215	A	C	MI.15297	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	157	53	M	L	Ata/Cta	-8,66	0	0	probably_damaging	0,96	neutral	0,66	neutral	1,19	neutral	1,73	neutral	-2,46	neutral_impact	0,68	neutral	0,83	neutral	0,85	neutral	1,65	14,15	0,27	0,45	neutral	0,09	neutral	0,32	disease	0,52	neutral	0,42	2	neutral	0,96	neutral	0,35	neutral	-2	deleterious	0,61	low_impact	-1,96	medium_impact	0,35	medium_impact	-0,49	0,3	0,8	0,87	7,08	N	0,31	N	0,98	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10215	10215	A	T	MI.15298	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	157	53	M	L	Ata/Tta	-8,66	0	0	probably_damaging	0,96	neutral	0,66	neutral	1,19	neutral	1,73	neutral	-2,46	neutral_impact	0,68	neutral	0,83	neutral	0,85	neutral	1,79	14,93	0,27	0,45	neutral	0,09	neutral	0,32	disease	0,52	neutral	0,42	2	neutral	0,96	neutral	0,35	neutral	-2	deleterious	0,61	low_impact	-1,96	medium_impact	0,35	medium_impact	-0,49	0,3	0,8	0,87	7,08	N	0,34	N	0,98	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10216	10216	T	A	MI.15299	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	158	53	M	K	aTa/aAa	2,21	0,96	0	probably_damaging	0,99	neutral	0,31	neutral	0,94	neutral	-1,68	deleterious	-5,59	high_impact	3,79	neutral	0,74	neutral	0,3	deleterious	3,98	23,6	0,02	0,35	disease	0,7	disease	0,87	disease	0,8	disease	0,75	5	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,86	low_impact	-2,52	medium_impact	0	high_impact	2,37	0,19	0,8	0,87	7,08	N	0,54	P	1	disease_causing	1	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8597	8597	T	C	MI.153	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	71	24	I	T	aTt/aCt	0,36	0,01	0,01	probably_damaging	0,99	neutral	0,53	neutral	3,91	deleterious	-3,91	deleterious	-3,73	low_impact	1,31	neutral	0,91	neutral	0,97	deleterious	3,07	22,4	0,49	0,65	neutral	0,45	neutral	0,22	neutral	0,36	neutral	0,37	3	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,67	low_impact	-2,65	medium_impact	0,32	medium_impact	0,03	0,61	0,9	18,14	17,22	N	0,39	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8405	8405	A	G	MI.1530	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	40	14	T	A	Acc/Gcc	-2,65	0	0	benign	0	neutral	0,2	neutral	1,99	neutral	-0,13	neutral	-1,03	low_impact	1,5	neutral	0,99	neutral	0,78	deleterious	0	2,61	0,7141844	0,85	neutral	0,29	neutral	0,13	neutral	0,45	neutral	0,06	9	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,13	high_impact	2,09	medium_impact	-0,05	medium_impact	0,19	0,54	0,85	NA	NA	N	0,53	P	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10216	10216	T	C	MI.15300	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	158	53	M	T	aTa/aCa	2,21	0,96	0	probably_damaging	0,99	neutral	0,4	neutral	0,99	neutral	-0,12	deleterious	-5,47	medium_impact	2,27	neutral	0,77	neutral	0,4	deleterious	2,98	22,2	0,12	0,4	disease	0,52	disease	0,69	disease	0,75	disease	0,72	4	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,79	low_impact	-2,52	medium_impact	0,09	medium_impact	0,97	0,14	0,8	0,87	7,08	N	0,4	N	0,99	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10217	10217	A	T	MI.15301	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	159	53	M	I	atA/atT	5,68	1	0,01	probably_damaging	0,99	neutral	0,4	neutral	1,18	neutral	1,65	deleterious	-3,46	low_impact	1,17	neutral	0,78	neutral	0,61	deleterious	2,21	17,56	0,34	0,5	neutral	0,14	neutral	0,37	disease	0,57	neutral	0,43	1	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,65	low_impact	-2,52	medium_impact	0,09	medium_impact	-0,04	0,51	0,8	0,87	7,08	P	0,55	P	0,96	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10217	10217	A	C	MI.15302	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	159	53	M	I	atA/atC	5,68	1	0,01	probably_damaging	0,99	neutral	0,4	neutral	1,18	neutral	1,65	deleterious	-3,46	low_impact	1,17	neutral	0,78	neutral	0,61	deleterious	2,13	17,06	0,34	0,5	neutral	0,14	neutral	0,37	disease	0,57	neutral	0,43	1	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,65	low_impact	-2,52	medium_impact	0,09	medium_impact	-0,04	0,51	0,8	0,87	7,08	P	0,55	P	0,96	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10218	10218	A	C	MI.15303	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	160	54	K	Q	Aaa/Caa	-0,1	0,91	0	probably_damaging	1	neutral	0,32	neutral	0,99	neutral	-1,14	deleterious	-3,54	low_impact	1,64	neutral	0,68	damaging	0,16	deleterious	3,43	23	0,3	0,45	neutral	0,37	disease	0,51	neutral	0,4	neutral	0,21	6	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,75	low_impact	-3,43	medium_impact	0,01	medium_impact	0,4	0,46	0,8	NA	NA	N	0,32	N	0,86	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10218	10218	A	G	MI.15304	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	160	54	K	E	Aaa/Gaa	-0,1	0,91	0	probably_damaging	1	neutral	0,27	neutral	0,95	neutral	-1,22	deleterious	-3,64	medium_impact	3,28	neutral	0,66	damaging	0,09	deleterious	4,04	23,7	0,13	0,4	neutral	0,43	disease	0,8	disease	0,66	disease	0,73	5	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	-0,05	medium_impact	1,9	0,52	0,8	NA	NA	N	0,37	N	0,86	polymorphism	1	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10219	10219	A	T	MI.15305	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	161	54	K	M	aAa/aTa	4,99	1	0	probably_damaging	1	neutral	0,24	neutral	0,84	deleterious	-3,96	deleterious	-5,46	high_impact	3,97	neutral	0,7	damaging	0,09	deleterious	3,85	23,4	0,06	0,35	disease	0,73	disease	0,64	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,8	low_impact	-3,43	medium_impact	-0,09	high_impact	2,53	0,22	0,8	NA	NA	P	0,62	P	0,54	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10219	10219	A	C	MI.15306	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	161	54	K	T	aAa/aCa	4,99	1	0	probably_damaging	1	neutral	0,42	neutral	0,91	neutral	-2,07	deleterious	-5,44	high_impact	3,62	neutral	0,67	damaging	0,09	deleterious	3,59	23,2	0,06	0,35	disease	0,52	disease	0,55	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,8	low_impact	-3,43	medium_impact	0,11	high_impact	2,21	0,26	0,8	NA	NA	P	0,58	P	0,81	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10220	10220	A	C	MI.15307	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	162	54	K	N	aaA/aaC	5,68	1	0	probably_damaging	1	neutral	0,32	neutral	0,91	neutral	-1,98	deleterious	-4,5	medium_impact	2,62	neutral	0,65	damaging	0,07	deleterious	3,74	23,3	0,4	0,5	disease	0,5	disease	0,74	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	0,01	medium_impact	1,29	0,43	0,8	NA	NA	P	0,59	P	0,71	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10220	10220	A	T	MI.15308	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	162	54	K	N	aaA/aaT	5,68	1	0	probably_damaging	1	neutral	0,32	neutral	0,91	neutral	-1,98	deleterious	-4,5	medium_impact	2,62	neutral	0,65	damaging	0,07	deleterious	3,81	23,4	0,4	0,5	disease	0,5	disease	0,74	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	0,01	medium_impact	1,29	0,43	0,8	NA	NA	P	0,6	P	0,71	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10221	10221	T	A	MI.15309	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	163	55	F	I	Ttc/Atc	0,59	0,99	0	probably_damaging	1	neutral	0,45	neutral	-0,05	deleterious	-6,44	deleterious	-5,77	high_impact	4,84	damaging	0,52	damaging	0,04	deleterious	4,61	24,5	0,05	0,35	disease	0,67	disease	0,88	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,83	low_impact	-3,43	medium_impact	0,14	high_impact	3,33	0,26	0,8	1,74	6,59	P	0,66	P	0,95	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8406	8406	C	T	MI.1531	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	41	14	T	I	aCc/aTc	-13,98	0	0	benign	0,08	neutral	0,75	neutral	2,1	neutral	1,15	neutral	0,79	neutral_impact	0,36	neutral	1	neutral	0,94	neutral	-0,55	0,16	0,56663707	0,85	neutral	0,14	neutral	0,18	neutral	0,35	neutral	0,07	9	neutral	0,15	deleterious	0,84	neutral	-6	neutral	0,15	medium_impact	0,25	medium_impact	0,56	medium_impact	-0,79	0,71	0,85	NA	NA	N	0,31	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10221	10221	T	G	MI.15310	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	163	55	F	V	Ttc/Gtc	0,59	0,99	0	probably_damaging	1	neutral	0,47	neutral	-0,05	deleterious	-6,36	deleterious	-6,73	high_impact	4,84	damaging	0,51	damaging	0,04	deleterious	4,17	23,8	0,04	0,35	disease	0,68	disease	0,9	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,83	low_impact	-3,43	medium_impact	0,16	high_impact	3,33	0,26	0,8	1,74	6,59	P	0,64	P	0,96	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10221	10221	T	C	MI.15311	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	163	55	F	L	Ttc/Ctc	0,59	0,99	0	probably_damaging	1	neutral	0,77	neutral	-0,01	deleterious	-4,91	deleterious	-5,77	high_impact	4,84	damaging	0,5	damaging	0,03	deleterious	4,16	23,8	0,04	0,35	disease	0,5	disease	0,83	disease	0,71	disease	0,68	4	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,79	low_impact	-3,43	medium_impact	0,48	high_impact	3,33	0,39	0,8	1,74	6,59	P	0,66	P	0,91	polymorphism	1	0,83	.	.	.	.	.	MNGIE tissues	.	.	.	.	.	.	.	.	.
chrM	10222	10222	T	A	MI.15312	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	164	55	F	Y	tTc/tAc	7,53	1	0	probably_damaging	1	neutral	0,88	neutral	0,43	neutral	-1,46	deleterious	-2,88	medium_impact	2,45	damaging	0,51	damaging	0,04	deleterious	4,44	24,2	0,09	0,35	neutral	0,46	disease	0,83	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,44	deleterious	1	deleterious	0,8	low_impact	-3,43	medium_impact	0,67	medium_impact	1,14	0,47	0,8	1,74	6,59	P	0,57	P	0,89	polymorphism	1	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10222	10222	T	C	MI.15313	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	164	55	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	neutral	0,44	neutral	-0,05	deleterious	-6,87	deleterious	-7,67	high_impact	4,84	damaging	0,52	damaging	0,04	deleterious	4,3	24	0,01	0,35	disease	0,79	disease	0,88	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	0,13	high_impact	3,33	0,25	0,8	1,74	6,59	P	0,63	P	0,97	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10222	10222	T	G	MI.15314	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	164	55	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	neutral	0,15	neutral	-0,06	deleterious	-8,39	deleterious	-7,71	high_impact	4,84	damaging	0,51	damaging	0,03	deleterious	4,11	23,7	0,02	0,35	disease	0,9	disease	0,88	disease	0,76	disease	0,61	2	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,84	low_impact	-3,43	medium_impact	-0,23	high_impact	3,33	0,22	0,8	1,74	6,59	P	0,6	P	0,99	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10223	10223	C	A	MI.15315	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	165	55	F	L	ttC/ttA	7,53	1	0	probably_damaging	1	neutral	0,77	neutral	-0,01	deleterious	-4,91	deleterious	-5,77	high_impact	4,84	damaging	0,5	damaging	0,03	deleterious	4,63	24,5	0,04	0,35	disease	0,5	disease	0,83	disease	0,71	disease	0,68	4	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,79	low_impact	-3,43	medium_impact	0,48	high_impact	3,33	0,39	0,8	1,74	6,59	P	0,7	P	0,91	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10223	10223	C	G	MI.15316	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	165	55	F	L	ttC/ttG	7,53	1	0	probably_damaging	1	neutral	0,77	neutral	-0,01	deleterious	-4,91	deleterious	-5,77	high_impact	4,84	damaging	0,5	damaging	0,03	deleterious	4,35	24,1	0,04	0,35	disease	0,5	disease	0,83	disease	0,71	disease	0,68	4	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,79	low_impact	-3,43	medium_impact	0,48	high_impact	3,33	0,39	0,8	1,74	6,59	P	0,7	P	0,91	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10224	10224	T	A	MI.15317	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	166	56	F	I	Ttc/Atc	-4,96	0	0	probably_damaging	1	neutral	0,18	neutral	0,38	neutral	-2,8	deleterious	-5,76	medium_impact	3,35	damaging	0,6	damaging	0,12	deleterious	4,31	24	0,07	0,35	disease	0,67	disease	0,89	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	-0,18	medium_impact	1,96	0,44	0,8	NA	NA	N	0,37	N	0,95	polymorphism	1	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10224	10224	T	C	MI.15318	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	166	56	F	L	Ttc/Ctc	-4,96	0	0	probably_damaging	1	neutral	0,32	neutral	0,42	neutral	-1,96	deleterious	-5,76	high_impact	4,12	damaging	0,57	damaging	0,11	deleterious	3,99	23,6	0,05	0,35	disease	0,5	disease	0,85	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,43	medium_impact	0,01	high_impact	2,67	0,54	0,8	NA	NA	N	0,42	N	0,91	polymorphism	1	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10224	10224	T	G	MI.15319	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	166	56	F	V	Ttc/Gtc	-4,96	0	0	probably_damaging	1	neutral	0,15	neutral	0,37	neutral	-2,83	deleterious	-6,72	high_impact	4,32	damaging	0,52	damaging	0,09	deleterious	4,01	23,6	0,05	0,35	disease	0,68	disease	0,91	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,82	low_impact	-3,43	medium_impact	-0,23	high_impact	2,85	0,29	0,8	NA	NA	N	0,42	N	0,96	polymorphism	1	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8406	8406	C	A	MI.1532	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	41	14	T	N	aCc/aAc	-13,98	0	0	benign	0,14	neutral	0,08	neutral	1,93	neutral	-2,68	neutral	-2,41	medium_impact	2,2	neutral	0,99	neutral	0,61	neutral	1,57	13,68	0,48904297	0,85	disease	0,55	neutral	0,3	disease	0,57	neutral	0,22	6	neutral	0,91	deleterious	0,47	neutral	-3	neutral	0,25	medium_impact	-0,01	medium_impact	-0,31	medium_impact	0,79	0,8	0,85	NA	NA	N	0,49	N	0,49	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10225	10225	T	C	MI.15320	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	167	56	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	neutral	0,13	neutral	0,38	deleterious	-3,66	deleterious	-7,66	high_impact	3,97	neutral	0,6	damaging	0,12	deleterious	4,22	23,9	0,02	0,35	disease	0,79	disease	0,89	disease	0,71	disease	0,67	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,85	low_impact	-3,43	medium_impact	-0,27	high_impact	2,53	0,15	0,8	NA	NA	P	0,66	P	0,97	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10225	10225	T	G	MI.15321	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	167	56	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	neutral	0,05	neutral	0,35	deleterious	-4,9	deleterious	-7,71	high_impact	3,77	damaging	0,58	damaging	0,09	deleterious	4,1	23,7	0,03	0,35	disease	0,9	disease	0,9	disease	0,75	disease	0,61	2	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,84	low_impact	-3,43	medium_impact	-0,52	high_impact	2,35	0,15	0,8	NA	NA	P	0,62	P	0,99	polymorphism	1	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10225	10225	T	A	MI.15322	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	167	56	F	Y	tTc/tAc	7,53	1	0	probably_damaging	1	neutral	0,14	neutral	1,05	neutral	2,91	deleterious	-2,88	low_impact	1,9	damaging	0,6	damaging	0,09	deleterious	4,23	23,9	0,09	0,4	neutral	0,46	disease	0,84	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,79	low_impact	-3,43	medium_impact	-0,25	medium_impact	0,63	0,51	0,8	NA	NA	P	0,57	P	0,89	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10226	10226	C	A	MI.15323	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	168	56	F	L	ttC/ttA	7,53	1	0	probably_damaging	1	neutral	0,32	neutral	0,42	neutral	-1,96	deleterious	-5,76	high_impact	4,12	damaging	0,57	damaging	0,11	deleterious	4,67	24,5	0,05	0,35	disease	0,5	disease	0,85	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,43	medium_impact	0,01	high_impact	2,67	0,54	0,8	NA	NA	P	0,65	P	0,91	polymorphism	1	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10226	10226	C	G	MI.15324	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	168	56	F	L	ttC/ttG	7,53	1	0	probably_damaging	1	neutral	0,32	neutral	0,42	neutral	-1,96	deleterious	-5,76	high_impact	4,12	damaging	0,57	damaging	0,11	deleterious	4,37	24,1	0,05	0,35	disease	0,5	disease	0,85	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,43	medium_impact	0,01	high_impact	2,67	0,54	0,8	NA	NA	P	0,65	P	0,91	polymorphism	1	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10227	10227	T	A	MI.15325	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	169	57	L	M	Tta/Ata	-1,95	0	0	probably_damaging	1	neutral	0,09	neutral	0,67	neutral	-2,34	neutral	-1,92	medium_impact	2,89	neutral	0,61	damaging	0,17	deleterious	3,48	23,1	0,16	0,45	disease	0,59	disease	0,56	disease	0,58	neutral	0,49	0	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,75	low_impact	-3,43	medium_impact	-0,37	medium_impact	1,54	0,47	0,8	NA	NA	N	0,34	N	0,91	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10227	10227	T	G	MI.15326	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	169	57	L	V	Tta/Gta	-1,95	0	0	probably_damaging	1	neutral	0,24	neutral	0,76	neutral	-1,5	deleterious	-2,88	medium_impact	3,17	damaging	0,43	damaging	0,06	deleterious	3,37	22,9	0,14	0,4	disease	0,51	disease	0,68	disease	0,61	disease	0,63	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,78	low_impact	-3,43	medium_impact	-0,09	medium_impact	1,8	0,46	0,8	NA	NA	N	0,43	N	0,89	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10228	10228	T	G	MI.15327	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	170	57	L	W	tTa/tGa	-0,57	0	0	probably_damaging	1	deleterious	0,04	neutral	0,6	deleterious	-5,97	deleterious	-5,79	high_impact	4,82	damaging	0,53	damaging	0,05	deleterious	3,75	23,3	0,04	0,35	disease	0,91	disease	0,76	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-3,43	medium_impact	-0,58	high_impact	3,31	0,22	0,8	NA	NA	P	0,54	P	0,98	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10228	10228	T	C	MI.15328	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	170	57	L	S	tTa/tCa	-0,57	0	0	probably_damaging	1	neutral	0,28	neutral	0,66	deleterious	-3,74	deleterious	-5,74	high_impact	4,26	damaging	0,51	damaging	0,06	deleterious	3,75	23,3	0,04	0,35	disease	0,8	disease	0,78	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-3,43	medium_impact	-0,04	high_impact	2,8	0,31	0,8	NA	NA	N	0,36	N	0,97	polymorphism	1	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10229	10229	A	C	MI.15329	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	171	57	L	F	ttA/ttC	7,53	0,96	0	probably_damaging	1	neutral	1	neutral	0,66	deleterious	-3,54	deleterious	-3,84	medium_impact	3,5	damaging	0,46	damaging	0,05	deleterious	3,45	23	0,12	0,4	disease	0,62	disease	0,74	disease	0,66	disease	0,66	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,81	low_impact	-3,43	high_impact	1,85	high_impact	2,1	0,48	0,8	NA	NA	N	0,52	P	0,99	polymorphism	1	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8406	8406	C	G	MI.1533	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	41	14	T	S	aCc/aGc	-13,98	0	0	benign	0,03	neutral	0,17	neutral	1,99	neutral	-0,27	neutral	-1,33	low_impact	1,16	neutral	1	neutral	0,87	neutral	1,36	12,57	0,53760445	0,85	neutral	0,39	neutral	0,17	neutral	0,36	neutral	0,12	8	neutral	0,82	deleterious	0,57	neutral	-6	neutral	0,14	medium_impact	0,68	medium_impact	-0,1	medium_impact	-0,1	0,75	0,85	NA	NA	P	0,54	P	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10229	10229	A	T	MI.15330	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	171	57	L	F	ttA/ttT	7,53	0,96	0	probably_damaging	1	neutral	1	neutral	0,66	deleterious	-3,54	deleterious	-3,84	medium_impact	3,5	damaging	0,46	damaging	0,05	deleterious	3,58	23,2	0,12	0,4	disease	0,62	disease	0,74	disease	0,66	disease	0,66	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,81	low_impact	-3,43	high_impact	1,85	high_impact	2,1	0,48	0,8	NA	NA	N	0,53	P	0,99	polymorphism	1	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10230	10230	G	A	MI.15331	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	172	58	V	M	Gta/Ata	-0,33	0	0	probably_damaging	0,95	neutral	0,05	neutral	0,74	neutral	-2,37	deleterious	-2,68	medium_impact	3,37	neutral	0,68	neutral	0,5	deleterious	3,62	23,2	0,09	0,35	disease	0,59	disease	0,74	disease	0,65	disease	0,65	3	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,72	low_impact	-1,87	medium_impact	-0,52	medium_impact	1,98	0,93	0,95	0,87	6,79	N	0,39	N	0,7	polymorphism	1	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10230	10230	G	C	MI.15332	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	172	58	V	L	Gta/Cta	-0,33	0	0	possibly_damaging	0,49	neutral	0,9	neutral	0,94	neutral	-0,28	neutral	-2,46	low_impact	1,9	neutral	0,69	neutral	0,49	deleterious	1,93	15,75	0,17	0,45	neutral	0,31	disease	0,76	disease	0,55	neutral	0,26	5	neutral	0,42	deleterious	0,71	neutral	-3	deleterious	0,55	medium_impact	-0,7	medium_impact	0,72	medium_impact	0,63	0,35	0,8	0,87	6,79	N	0,26	N	0,66	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10230	10230	G	T	MI.15333	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	172	58	V	L	Gta/Tta	-0,33	0	0	possibly_damaging	0,49	neutral	0,9	neutral	0,94	neutral	-0,28	neutral	-2,46	low_impact	1,9	neutral	0,69	neutral	0,49	deleterious	2,09	16,78	0,17	0,45	neutral	0,31	disease	0,76	disease	0,55	neutral	0,26	5	neutral	0,42	deleterious	0,71	neutral	-3	deleterious	0,55	medium_impact	-0,7	medium_impact	0,72	medium_impact	0,63	0,35	0,8	0,87	6,79	N	0,27	N	0,66	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10231	10231	T	G	MI.15334	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	173	58	V	G	gTa/gGa	1,52	0,95	0	possibly_damaging	0,82	neutral	0,11	neutral	0,69	deleterious	-4,12	deleterious	-6,75	high_impact	4,41	neutral	0,66	neutral	0,51	deleterious	2,24	17,76	0,03	0,35	disease	0,81	disease	0,85	disease	0,64	disease	0,66	3	neutral	0,94	neutral	0,15	deleterious	1	deleterious	0,72	low_impact	-1,31	medium_impact	-0,31	high_impact	2,94	0,24	0,8	0,87	6,79	P	0,59	P	0,95	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10231	10231	T	A	MI.15335	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	173	58	V	E	gTa/gAa	1,52	0,95	0	probably_damaging	0,94	neutral	0,06	neutral	0,69	deleterious	-4,28	deleterious	-5,79	high_impact	4,41	neutral	0,69	neutral	0,38	deleterious	4,74	24,7	0,03	0,35	disease	0,82	disease	0,88	disease	0,75	disease	0,69	4	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,81	low_impact	-1,8	medium_impact	-0,47	high_impact	2,94	0,2	0,8	0,87	6,79	P	0,6	P	0,98	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10231	10231	T	C	MI.15336	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	173	58	V	A	gTa/gCa	1,52	0,95	0	benign	0,08	neutral	0,28	neutral	0,74	neutral	-2,31	deleterious	-3,83	high_impact	4,05	neutral	0,71	neutral	0,55	neutral	1,64	14,07	0,07	0,35	disease	0,52	disease	0,63	disease	0,62	disease	0,63	3	neutral	0,69	deleterious	0,6	neutral	-2	neutral	0,24	medium_impact	0,24	medium_impact	-0,04	high_impact	2,61	0,17	0,8	0,87	6,79	P	0,54	P	0,75	polymorphism	1	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10233	10233	G	T	MI.15337	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	175	59	A	S	Gct/Tct	-4,04	0	0	probably_damaging	1	neutral	0,23	neutral	0,8	deleterious	-3,64	deleterious	-2,75	medium_impact	2,62	damaging	0,55	damaging	0,06	deleterious	3,68	23,3	0,11	0,4	neutral	0,39	disease	0,8	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,79	low_impact	-3,43	medium_impact	-0,1	medium_impact	1,29	0,55	0,8	2,61	7,03	N	0,29	N	0,98	polymorphism	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10233	10233	G	C	MI.15338	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	175	59	A	P	Gct/Cct	-4,04	0	0	probably_damaging	1	deleterious	0,04	neutral	0,67	deleterious	-6,1	deleterious	-4,71	high_impact	4,2	damaging	0,48	damaging	0,04	deleterious	3,79	23,4	0,02	0,35	disease	0,67	disease	0,86	disease	0,77	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-3,43	medium_impact	-0,58	high_impact	2,74	0,48	0,8	2,61	7,03	N	0,41	N	0,96	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10233	10233	G	A	MI.15339	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	175	59	A	T	Gct/Act	-4,04	0	0	probably_damaging	1	neutral	0,15	neutral	0,74	deleterious	-4,39	deleterious	-3,75	medium_impact	2,95	damaging	0,47	damaging	0,06	deleterious	4,2	23,9	0,07	0,35	neutral	0,29	disease	0,75	disease	0,63	disease	0,55	1	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,77	low_impact	-3,43	medium_impact	-0,23	medium_impact	1,6	0,72	0,85	2,61	7,03	N	0,37	N	0,93	polymorphism	1	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8408	8408	C	A	MI.1534	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	43	15	P	T	Ccc/Acc	-5,66	0	0	probably_damaging	1	neutral	0,21	neutral	2,06	neutral	1,47	neutral	0,62	neutral_impact	-0,34	neutral	0,97	neutral	0,9	deleterious	0,79	9,41	0,48647755	0,85	neutral	0,36	neutral	0,07	neutral	0,35	neutral	0,04	9	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,66	low_impact	-3,6	medium_impact	-0,03	low_impact	-1,39	0,77	0,85	8,82	7,31	P	0,56	P	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10234	10234	C	T	MI.15340	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	176	59	A	V	gCt/gTt	9,15	1	0	probably_damaging	1	neutral	0,9	neutral	0,83	deleterious	-5,38	deleterious	-3,81	medium_impact	3,3	damaging	0,42	damaging	0,05	deleterious	4,36	24,1	0,05	0,35	disease	0,53	disease	0,84	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,45	deleterious	1	deleterious	0,8	low_impact	-3,43	medium_impact	0,72	medium_impact	1,92	0,66	0,8	2,61	7,03	P	0,65	P	0,79	polymorphism	1	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10234	10234	C	A	MI.15341	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	176	59	A	D	gCt/gAt	9,15	1	0	probably_damaging	1	deleterious	0,04	neutral	0,68	deleterious	-6,18	deleterious	-5,57	high_impact	4,75	damaging	0,57	damaging	0,04	deleterious	4,55	24,4	0,02	0,35	disease	0,7	disease	0,9	disease	0,77	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-3,43	medium_impact	-0,58	high_impact	3,25	0,35	0,8	2,61	7,03	P	0,69	P	0,96	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10234	10234	C	G	MI.15342	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	176	59	A	G	gCt/gGt	9,15	1	0	probably_damaging	1	neutral	0,11	neutral	0,71	deleterious	-4,12	deleterious	-3,46	medium_impact	2,18	damaging	0,54	neutral	0,62	deleterious	2,84	21,6	0,09	0,35	disease	0,5	disease	0,76	disease	0,62	neutral	0,34	3	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,77	low_impact	-3,43	medium_impact	-0,31	medium_impact	0,89	0,66	0,8	2,61	7,03	P	0,58	P	0,85	polymorphism	1	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10236	10236	A	G	MI.15343	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	178	60	I	V	Att/Gtt	-8,89	0	0	possibly_damaging	0,64	neutral	0,22	neutral	0,96	neutral	-1,31	neutral	-0,95	low_impact	1,92	damaging	0,58	neutral	0,43	deleterious	3,01	22,3	0,35	0,5	neutral	0,19	neutral	0,37	neutral	0,43	neutral	0,39	2	neutral	0,8	neutral	0,29	neutral	-3	deleterious	0,5	medium_impact	-0,94	medium_impact	-0,12	medium_impact	0,65	0,61	0,8	1,74	7,14	N	0,47	N	0,79	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10236	10236	A	T	MI.15344	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	178	60	I	F	Att/Ttt	-8,89	0	0	probably_damaging	0,92	neutral	0,58	neutral	0,72	neutral	-2,82	deleterious	-3,74	high_impact	4,31	damaging	0,53	neutral	0,33	deleterious	4	23,6	0,08	0,35	disease	0,62	disease	0,83	disease	0,65	disease	0,67	3	neutral	0,91	neutral	0,33	deleterious	2	deleterious	0,79	low_impact	-1,68	medium_impact	0,27	high_impact	2,84	0,62	0,8	1,74	7,14	N	0,4	N	0,97	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10236	10236	A	C	MI.15345	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	178	60	I	L	Att/Ctt	-8,89	0	0	benign	0,12	neutral	0,54	neutral	1,08	neutral	0,78	neutral	-1,77	medium_impact	2,32	damaging	0,5	neutral	0,37	deleterious	3,74	23,3	0,22	0,45	neutral	0,29	disease	0,72	disease	0,51	disease	0,53	1	neutral	0,37	deleterious	0,71	neutral	-3	neutral	0,23	medium_impact	0,06	medium_impact	0,23	medium_impact	1,02	0,62	0,8	1,74	7,14	N	0,38	N	0,85	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10237	10237	T	A	MI.15346	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	179	60	I	N	aTt/aAt	4,76	1	0	probably_damaging	0,99	deleterious	0,03	neutral	0,68	deleterious	-5,01	deleterious	-6,62	high_impact	3,96	damaging	0,5	neutral	0,31	deleterious	4,37	24,1	0,06	0,35	disease	0,82	disease	0,86	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,83	low_impact	-2,52	medium_impact	-0,65	high_impact	2,52	0,34	0,8	1,74	7,14	P	0,57	P	0,99	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10237	10237	T	G	MI.15347	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	179	60	I	S	aTt/aGt	4,76	1	0	probably_damaging	0,97	deleterious	0,04	neutral	0,7	deleterious	-3,86	deleterious	-5,64	high_impact	4,66	damaging	0,55	neutral	0,38	deleterious	4,25	23,9	0,03	0,35	disease	0,71	disease	0,84	disease	0,61	disease	0,67	3	deleterious	0,99	neutral	0,04	deleterious	6	deleterious	0,81	low_impact	-2,08	medium_impact	-0,58	high_impact	3,16	0,28	0,8	1,74	7,14	P	0,64	P	0,96	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10237	10237	T	C	MI.15348	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	179	60	I	T	aTt/aCt	4,76	1	0	probably_damaging	0,96	neutral	0,09	neutral	0,71	deleterious	-3,14	deleterious	-4,68	high_impact	3,86	damaging	0,43	neutral	0,37	deleterious	3,33	22,9	0,06	0,35	disease	0,53	disease	0,7	disease	0,59	disease	0,64	3	deleterious	0,98	neutral	0,07	deleterious	2	deleterious	0,77	low_impact	-1,96	medium_impact	-0,37	high_impact	2,43	0,28	0,8	1,74	7,14	P	0,79	P	0,99	disease_causing_automatic	0	0,74	rs193302927	Pathogenic	Leber's_optic_atrophy	RCV000055695.1	MedGen:OMIM:SNOMED_CT	.	.	CPD	0,15	T10237C	LHON	+	-	Reported	1
chrM	10238	10238	T	A	MI.15349	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	180	60	I	M	atT/atA	7,53	1	0,08	probably_damaging	0,97	neutral	0,17	neutral	0,77	neutral	-0,35	deleterious	-2,76	medium_impact	2,66	damaging	0,57	neutral	0,38	deleterious	3,68	23,3	0,19	0,45	disease	0,54	disease	0,66	disease	0,56	neutral	0,5	0	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,72	low_impact	-2,08	medium_impact	-0,19	medium_impact	1,33	0,54	0,8	1,74	7,14	P	0,66	P	0,78	polymorphism	1	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8408	8408	C	T	MI.1535	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	43	15	P	S	Ccc/Tcc	-5,66	0	0	probably_damaging	1	neutral	0,62	neutral	2,2	neutral	2,94	neutral	2,01	neutral_impact	-2,1	neutral	1	neutral	0,97	neutral	1,03	10,83	0,60673599	0,85	neutral	0,11	neutral	0,04	neutral	0,4	neutral	0,04	9	deleterious	0,99	neutral	0,31	neutral	-2	deleterious	0,62	low_impact	-3,6	medium_impact	0,41	low_impact	-2,9	0,46	0,85	8,82	7,31	N	0,4	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10238	10238	T	G	MI.15350	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	180	60	I	M	atT/atG	7,53	1	0,08	probably_damaging	0,97	neutral	0,17	neutral	0,77	neutral	-0,35	deleterious	-2,76	medium_impact	2,66	damaging	0,57	neutral	0,38	deleterious	3,39	23	0,19	0,45	disease	0,54	disease	0,66	disease	0,56	neutral	0,5	0	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,72	low_impact	-2,08	medium_impact	-0,19	medium_impact	1,33	0,54	0,8	1,74	7,14	P	0,66	P	0,78	polymorphism	1	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10239	10239	A	C	MI.15351	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	181	61	T	P	Acc/Ccc	-2,19	0	0	benign	0,19	deleterious	0,02	neutral	0,94	neutral	-2,19	deleterious	-4,92	medium_impact	2,81	damaging	0,57	damaging	0,05	deleterious	2,3	18,16	0,05	0,35	disease	0,6	disease	0,92	disease	0,65	disease	0,75	5	neutral	0,98	neutral	0,42	deleterious	1	neutral	0,43	medium_impact	-0,15	medium_impact	-0,75	medium_impact	1,47	0,27	0,8	2,61	6,75	N	0,25	N	0,98	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10239	10239	A	T	MI.15352	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	181	61	T	S	Acc/Tcc	-2,19	0	0	probably_damaging	0,94	neutral	0,07	neutral	0,99	neutral	-0,25	deleterious	-3,39	medium_impact	2,46	neutral	0,78	damaging	0,11	neutral	1,44	13	0,3	0,45	neutral	0,38	disease	0,63	disease	0,52	disease	0,57	1	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,7	low_impact	-1,8	medium_impact	-0,43	medium_impact	1,15	0,36	0,8	2,61	6,75	N	0,34	N	0,89	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10239	10239	A	G	MI.15353	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	181	61	T	A	Acc/Gcc	-2,19	0	0	possibly_damaging	0,87	neutral	0,37	neutral	1,01	neutral	0,18	deleterious	-4,12	medium_impact	2,56	neutral	0,71	damaging	0,11	deleterious	2,15	17,18	0,22	0,45	neutral	0,28	disease	0,56	disease	0,52	disease	0,56	1	neutral	0,87	neutral	0,25	NA	0	deleterious	0,66	low_impact	-1,46	medium_impact	0,06	medium_impact	1,24	0,26	0,8	2,61	6,75	N	0,31	N	0,72	polymorphism	1	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10240	10240	C	T	MI.15354	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	182	61	T	I	aCc/aTc	1,29	0,45	0	probably_damaging	0,99	neutral	1	neutral	1,16	neutral	1,78	deleterious	-4,73	neutral_impact	0,42	neutral	0,69	damaging	0,1	deleterious	2,67	20,6	0,13	0,4	neutral	0,12	disease	0,71	neutral	0,34	neutral	0,21	6	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,68	low_impact	-2,52	high_impact	1,85	medium_impact	-0,72	0,46	0,8	2,61	6,75	N	0,23	N	0,96	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10240	10240	C	G	MI.15355	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	182	61	T	S	aCc/aGc	1,29	0,45	0	probably_damaging	0,94	neutral	0,07	neutral	0,99	neutral	-0,25	deleterious	-3,39	medium_impact	2,46	neutral	0,78	damaging	0,11	neutral	1,66	14,16	0,3	0,45	neutral	0,38	disease	0,63	disease	0,52	disease	0,57	1	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,7	low_impact	-1,8	medium_impact	-0,43	medium_impact	1,15	0,36	0,8	2,61	6,75	N	0,31	N	0,89	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10240	10240	C	A	MI.15356	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	182	61	T	N	aCc/aAc	1,29	0,45	0	probably_damaging	0,98	deleterious	0,02	neutral	0,95	neutral	-1,88	deleterious	-4,37	medium_impact	3,36	neutral	0,66	damaging	0,08	deleterious	2,48	19,36	0,3	0,45	disease	0,53	disease	0,83	disease	0,55	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-2,24	medium_impact	-0,75	medium_impact	1,97	0,4	0,8	2,61	6,75	N	0,31	N	0,94	polymorphism	1	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10242	10242	T	G	MI.15357	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	184	62	F	V	Ttc/Gtc	-3,34	0	0	probably_damaging	1	neutral	0,29	neutral	-0,47	deleterious	-6,43	deleterious	-6,54	high_impact	4,93	damaging	0,51	damaging	0,04	deleterious	4,11	23,8	0,07	0,35	disease	0,67	disease	0,91	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-3,43	medium_impact	-0,03	high_impact	3,41	0,24	0,8	1,74	6,65	P	0,54	P	0,96	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10242	10242	T	A	MI.15358	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	184	62	F	I	Ttc/Atc	-3,34	0	0	probably_damaging	1	neutral	0,46	neutral	-0,47	deleterious	-6,38	deleterious	-5,6	high_impact	4,12	damaging	0,52	damaging	0,04	deleterious	4,42	24,2	0,06	0,35	disease	0,66	disease	0,9	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,82	low_impact	-3,43	medium_impact	0,15	high_impact	2,67	0,31	0,8	1,74	6,65	N	0,38	N	0,95	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10242	10242	T	C	MI.15359	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	184	62	F	L	Ttc/Ctc	-3,34	0	0	probably_damaging	1	neutral	1	neutral	-0,4	deleterious	-4,59	deleterious	-5,6	high_impact	4,24	damaging	0,5	damaging	0,03	deleterious	4,08	23,7	0,06	0,35	neutral	0,5	disease	0,88	disease	0,68	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,79	low_impact	-3,43	high_impact	1,85	high_impact	2,78	0,35	0,8	1,74	6,65	N	0,39	N	0,91	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8408	8408	C	G	MI.1536	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	43	15	P	A	Ccc/Gcc	-5,66	0	0	probably_damaging	0,99	neutral	0,26	neutral	2,06	neutral	1,62	neutral	0,31	neutral_impact	-0,06	neutral	0,99	neutral	0,91	neutral	1,03	10,8	0,41328743	0,85	neutral	0,26	neutral	0,05	neutral	0,36	neutral	0,04	9	deleterious	0,99	neutral	0,14	neutral	-2	deleterious	0,67	low_impact	-2,65	medium_impact	0,04	low_impact	-1,15	0,76	0,85	8,82	7,31	P	0,6	P	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10243	10243	T	C	MI.15360	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	185	62	F	S	tTc/tCc	5,68	1	0	probably_damaging	1	deleterious	0,04	neutral	-0,49	deleterious	-7,45	deleterious	-7,46	high_impact	4,58	damaging	0,52	damaging	0,04	deleterious	4,23	23,9	0,03	0,35	disease	0,78	disease	0,89	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,83	low_impact	-3,43	medium_impact	-0,58	high_impact	3,09	0,13	0,8	1,74	6,65	P	0,56	P	0,97	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10243	10243	T	A	MI.15361	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	185	62	F	Y	tTc/tAc	5,68	1	0	probably_damaging	1	neutral	0,06	neutral	-0,34	deleterious	-3,9	deleterious	-2,8	high_impact	3,77	damaging	0,51	damaging	0,04	deleterious	4,22	23,9	0,09	0,4	neutral	0,45	disease	0,85	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,79	low_impact	-3,43	medium_impact	-0,47	high_impact	2,35	0,5	0,8	1,74	6,65	P	0,62	P	0,89	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10243	10243	T	G	MI.15362	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	185	62	F	C	tTc/tGc	5,68	1	0	probably_damaging	1	deleterious	0,01	neutral	-0,5	deleterious	-8,88	deleterious	-7,48	high_impact	4,93	damaging	0,51	damaging	0,03	deleterious	4,12	23,8	0,04	0,35	disease	0,9	disease	0,9	disease	0,74	disease	0,62	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,43	medium_impact	-0,92	high_impact	3,41	0,12	0,8	1,74	6,65	P	0,58	P	0,99	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10244	10244	C	A	MI.15363	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	186	62	F	L	ttC/ttA	7,53	1	0	probably_damaging	1	neutral	1	neutral	-0,4	deleterious	-4,59	deleterious	-5,6	high_impact	4,24	damaging	0,5	damaging	0,03	deleterious	4,69	24,6	0,06	0,35	neutral	0,5	disease	0,88	disease	0,68	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,79	low_impact	-3,43	high_impact	1,85	high_impact	2,78	0,35	0,8	1,74	6,65	P	0,58	P	0,91	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10244	10244	C	G	MI.15364	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	186	62	F	L	ttC/ttG	7,53	1	0	probably_damaging	1	neutral	1	neutral	-0,4	deleterious	-4,59	deleterious	-5,6	high_impact	4,24	damaging	0,5	damaging	0,03	deleterious	4,39	24,1	0,06	0,35	neutral	0,5	disease	0,88	disease	0,68	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,79	low_impact	-3,43	high_impact	1,85	high_impact	2,78	0,35	0,8	1,74	6,65	P	0,58	P	0,91	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10245	10245	T	G	MI.15365	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	187	63	L	V	Tta/Gta	-3,34	0	0	probably_damaging	0,92	neutral	0,38	neutral	1	neutral	0,03	deleterious	-2,88	medium_impact	2,52	damaging	0,43	neutral	0,28	deleterious	3,12	22,6	0,17	0,45	neutral	0,44	disease	0,66	disease	0,63	disease	0,65	3	neutral	0,92	neutral	0,23	deleterious	1	deleterious	0,74	low_impact	-1,68	medium_impact	0,07	medium_impact	1,2	0,4	0,8	2,61	6,7	N	0,45	N	0,89	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10245	10245	T	A	MI.15366	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	187	63	L	M	Tta/Ata	-3,34	0	0	probably_damaging	0,98	neutral	0,16	neutral	0,68	deleterious	-3,06	neutral	-1,93	medium_impact	3,34	damaging	0,57	neutral	0,43	deleterious	3,45	23	0,12	0,4	disease	0,56	disease	0,63	disease	0,58	disease	0,62	2	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,74	low_impact	-2,24	medium_impact	-0,21	medium_impact	1,95	0,34	0,8	2,61	6,7	N	0,4	N	0,91	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10246	10246	T	G	MI.15367	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	188	63	L	W	tTa/tGa	-0,33	0	0	probably_damaging	1	deleterious	0,01	neutral	0,61	deleterious	-6,61	deleterious	-5,74	high_impact	4,72	damaging	0,51	damaging	0,26	deleterious	3,77	23,4	0,04	0,35	disease	0,88	disease	0,81	disease	0,68	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,43	medium_impact	-0,92	high_impact	3,22	0,2	0,8	2,61	6,7	P	0,55	P	0,98	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10246	10246	T	C	MI.15368	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	188	63	L	S	tTa/tCa	-0,33	0	0	probably_damaging	0,91	neutral	0,12	neutral	0,64	deleterious	-4,55	deleterious	-5,71	high_impact	4,38	damaging	0,49	neutral	0,33	deleterious	3,55	23,1	0,04	0,35	disease	0,63	disease	0,78	disease	0,66	disease	0,66	3	neutral	0,96	neutral	0,11	deleterious	2	deleterious	0,79	low_impact	-1,62	medium_impact	-0,29	high_impact	2,91	0,22	0,8	2,61	6,7	N	0,48	N	0,97	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10247	10247	A	C	MI.15369	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	189	63	L	F	ttA/ttC	4,52	0,69	0	probably_damaging	0,98	neutral	1	neutral	0,65	deleterious	-3,65	deleterious	-3,85	high_impact	4,17	damaging	0,54	neutral	0,34	deleterious	3,44	23	0,12	0,4	disease	0,58	disease	0,76	disease	0,66	disease	0,65	3	deleterious	0,98	deleterious	0,51	deleterious	2	deleterious	0,8	low_impact	-2,24	high_impact	1,85	high_impact	2,72	0,33	0,8	2,61	6,7	N	0,46	N	0,99	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8409	8409	C	T	MI.1537	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	44	15	P	L	cCc/cTc	-1,26	0	0	probably_damaging	1	neutral	0,86	neutral	2,2	neutral	2,95	neutral	-2,07	neutral_impact	-0,52	neutral	1	neutral	0,67	deleterious	3,08	22,5	0,60355318	0,85	disease	0,56	neutral	0,2	neutral	0,36	neutral	0,12	8	deleterious	1	neutral	0,43	neutral	-2	deleterious	0,72	low_impact	-3,6	medium_impact	0,74	low_impact	-1,54	0,74	0,85	8,82	7,31	N	0,33	N	0,17	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10247	10247	A	T	MI.15370	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	189	63	L	F	ttA/ttT	4,52	0,69	0	probably_damaging	0,98	neutral	1	neutral	0,65	deleterious	-3,65	deleterious	-3,85	high_impact	4,17	damaging	0,54	neutral	0,34	deleterious	3,51	23,1	0,12	0,4	disease	0,58	disease	0,76	disease	0,66	disease	0,65	3	deleterious	0,98	deleterious	0,51	deleterious	2	deleterious	0,8	low_impact	-2,24	high_impact	1,85	high_impact	2,72	0,33	0,8	2,61	6,7	N	0,47	N	0,99	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10248	10248	T	G	MI.15371	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	190	64	L	V	Tta/Gta	-20	0	0	probably_damaging	1	neutral	0,28	neutral	1,02	neutral	0,07	deleterious	-2,87	low_impact	1,52	neutral	0,67	damaging	0,06	deleterious	3,39	23	0,23	0,45	neutral	0,31	disease	0,59	neutral	0,5	neutral	0,39	2	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,72	low_impact	-3,43	medium_impact	-0,04	medium_impact	0,29	0,4	0,8	NA	NA	N	0,26	N	0,89	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10248	10248	T	A	MI.15372	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	190	64	L	M	Tta/Ata	-20	0	0	probably_damaging	1	neutral	0,07	neutral	0,69	neutral	-2,82	neutral	-1,93	medium_impact	2,88	neutral	0,66	damaging	0,06	deleterious	3,53	23,1	0,15	0,4	neutral	0,46	disease	0,57	disease	0,58	disease	0,61	2	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,72	low_impact	-3,43	medium_impact	-0,43	medium_impact	1,53	0,42	0,8	NA	NA	N	0,3	N	0,91	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10249	10249	T	G	MI.15373	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	191	64	L	W	tTa/tGa	-1,72	0	0	probably_damaging	1	deleterious	0,03	neutral	0,64	deleterious	-6,04	deleterious	-5,74	high_impact	4,26	neutral	0,61	damaging	0,04	deleterious	3,74	23,3	0,05	0,35	disease	0,88	disease	0,8	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,83	low_impact	-3,43	medium_impact	-0,65	high_impact	2,8	0,2	0,8	NA	NA	N	0,32	N	0,98	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10249	10249	T	C	MI.15374	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	191	64	L	S	tTa/tCa	-1,72	0	0	probably_damaging	1	neutral	0,06	neutral	0,66	deleterious	-3,88	deleterious	-5,71	high_impact	3,92	neutral	0,62	damaging	0,04	deleterious	3,84	23,4	0,05	0,35	disease	0,76	disease	0,73	disease	0,61	disease	0,63	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,81	low_impact	-3,43	medium_impact	-0,47	high_impact	2,49	0,23	0,8	NA	NA	N	0,3	N	0,97	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10250	10250	A	C	MI.15375	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	192	64	L	F	ttA/ttC	7,53	0,96	0	probably_damaging	1	neutral	0,67	neutral	0,68	deleterious	-3,23	deleterious	-3,86	high_impact	3,92	neutral	0,6	damaging	0,04	deleterious	3,52	23,1	0,14	0,4	disease	0,51	disease	0,73	disease	0,6	disease	0,62	2	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,77	low_impact	-3,43	medium_impact	0,36	high_impact	2,49	0,33	0,8	NA	NA	N	0,5	N	0,99	polymorphism	1	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10250	10250	A	T	MI.15376	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	192	64	L	F	ttA/ttT	7,53	0,96	0	probably_damaging	1	neutral	0,67	neutral	0,68	deleterious	-3,23	deleterious	-3,86	high_impact	3,92	neutral	0,6	damaging	0,04	deleterious	3,56	23,1	0,14	0,4	disease	0,51	disease	0,73	disease	0,6	disease	0,62	2	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,77	low_impact	-3,43	medium_impact	0,36	high_impact	2,49	0,33	0,8	NA	NA	N	0,5	N	0,99	polymorphism	1	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10251	10251	T	C	MI.15377	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	193	65	F	L	Ttt/Ctt	-3,11	0	0	probably_damaging	1	neutral	1	neutral	-0,64	deleterious	-6,03	deleterious	-5,69	high_impact	3,88	damaging	0,58	damaging	0,09	deleterious	3,91	23,5	0,06	0,35	neutral	0,5	disease	0,87	disease	0,7	disease	0,69	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,78	low_impact	-3,43	high_impact	1,85	high_impact	2,45	0,16	0,8	1,74	6,53	N	0,34	N	0,91	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10251	10251	T	A	MI.15378	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	193	65	F	I	Ttt/Att	-3,11	0	0	probably_damaging	1	neutral	0,46	neutral	-0,67	deleterious	-7,29	deleterious	-5,68	high_impact	4,24	damaging	0,6	damaging	0,09	deleterious	4,28	24	0,09	0,35	disease	0,66	disease	0,87	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,8	low_impact	-3,43	medium_impact	0,15	high_impact	2,78	0,24	0,8	1,74	6,53	N	0,42	N	0,95	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10251	10251	T	G	MI.15379	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	193	65	F	V	Ttt/Gtt	-3,11	0	0	probably_damaging	1	neutral	0,12	neutral	-0,67	deleterious	-7,25	deleterious	-6,62	high_impact	4,58	neutral	0,61	damaging	0,12	deleterious	3,9	23,5	0,09	0,35	disease	0,67	disease	0,88	disease	0,76	disease	0,7	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,81	low_impact	-3,43	medium_impact	-0,29	high_impact	3,09	0,18	0,8	1,74	6,53	N	0,48	N	0,96	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8409	8409	C	A	MI.1538	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	44	15	P	H	cCc/cAc	-1,26	0	0	probably_damaging	1	neutral	0,17	neutral	1,98	neutral	-1,41	neutral	-1,54	low_impact	1,36	neutral	0,95	neutral	0,44	deleterious	3,79	23,4	0,47634976	0,85	disease	0,7	neutral	0,21	disease	0,66	neutral	0,16	7	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	-0,1	medium_impact	0,07	0,62	0,85	8,82	7,31	N	0,48	N	0,44	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10252	10252	T	A	MI.15380	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	194	65	F	Y	tTt/tAt	7,53	1	0	probably_damaging	1	neutral	0,09	neutral	-0,51	deleterious	-4,02	deleterious	-2,85	high_impact	4,92	neutral	0,64	damaging	0,1	deleterious	4,27	24	0,12	0,4	neutral	0,45	disease	0,81	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,78	low_impact	-3,43	medium_impact	-0,37	high_impact	3,4	0,38	0,8	1,74	6,53	P	0,77	P	0,89	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10252	10252	T	C	MI.15381	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	194	65	F	S	tTt/tCt	7,53	1	0	probably_damaging	1	deleterious	0,04	neutral	-0,68	deleterious	-7,87	deleterious	-7,59	high_impact	4,38	neutral	0,6	damaging	0,09	deleterious	4,26	23,9	0,05	0,35	disease	0,78	disease	0,87	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,83	low_impact	-3,43	medium_impact	-0,58	high_impact	2,91	0,13	0,8	1,74	6,53	P	0,57	P	0,97	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10252	10252	T	G	MI.15382	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	194	65	F	C	tTt/tGt	7,53	1	0	probably_damaging	1	deleterious	0,02	neutral	-0,69	deleterious	-9,36	deleterious	-7,5	high_impact	4,92	neutral	0,62	damaging	0,09	deleterious	4,09	23,7	0,05	0,35	disease	0,9	disease	0,87	disease	0,74	disease	0,61	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-3,43	medium_impact	-0,75	high_impact	3,4	0,12	0,8	1,74	6,53	P	0,63	P	0,99	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10253	10253	T	G	MI.15383	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	195	65	F	L	ttT/ttG	5,68	1	0	probably_damaging	1	neutral	1	neutral	-0,64	deleterious	-6,03	deleterious	-5,69	high_impact	3,88	damaging	0,58	damaging	0,09	deleterious	4,32	24	0,06	0,35	neutral	0,5	disease	0,87	disease	0,7	disease	0,69	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,78	low_impact	-3,43	high_impact	1,85	high_impact	2,45	0,16	0,8	1,74	6,53	P	0,56	P	0,91	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10253	10253	T	A	MI.15384	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	195	65	F	L	ttT/ttA	5,68	1	0	probably_damaging	1	neutral	1	neutral	-0,64	deleterious	-6,03	deleterious	-5,69	high_impact	3,88	damaging	0,58	damaging	0,09	deleterious	4,41	24,1	0,06	0,35	neutral	0,5	disease	0,87	disease	0,7	disease	0,69	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,78	low_impact	-3,43	high_impact	1,85	high_impact	2,45	0,16	0,8	1,74	6,53	P	0,57	P	0,91	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10254	10254	G	A	MI.15385	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	196	66	D	N	Gat/Aat	-3,34	0	0	probably_damaging	1	neutral	0,11	neutral	-0,36	deleterious	-5,25	deleterious	-4,77	high_impact	4,58	damaging	0,39	damaging	0,05	deleterious	4,18	23,8	0,29	0,45	disease	0,63	disease	0,82	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,81	low_impact	-3,43	medium_impact	-0,31	high_impact	3,09	0,65	0,8	0,87	6,92	P	0,56	P	0,98	disease_causing_automatic	0	0,84	rs587776438	Pathogenic	Leigh_syndrome	RCV000144012.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	G10254A	Leigh Disease	-	+	Reported	1
chrM	10254	10254	G	C	MI.15386	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	196	66	D	H	Gat/Cat	-3,34	0	0	probably_damaging	1	neutral	0,18	neutral	-0,4	deleterious	-7,07	deleterious	-6,7	high_impact	4,58	damaging	0,48	damaging	0,04	deleterious	3,62	23,2	0,07	0,35	disease	0,83	disease	0,88	disease	0,8	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,43	medium_impact	-0,18	high_impact	3,09	0,37	0,8	0,87	6,92	N	0,48	N	0,99	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10254	10254	G	T	MI.15387	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	196	66	D	Y	Gat/Tat	-3,34	0	0	probably_damaging	1	neutral	0,34	neutral	-0,41	deleterious	-8,27	deleterious	-8,62	high_impact	4,93	damaging	0,5	damaging	0,04	deleterious	3,9	23,5	0,04	0,35	disease	0,89	disease	0,92	disease	0,8	disease	0,63	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,87	low_impact	-3,43	medium_impact	0,03	high_impact	3,41	0,15	0,8	0,87	6,92	P	0,54	P	1	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10255	10255	A	C	MI.15388	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	197	66	D	A	gAt/gCt	7,3	1	0	probably_damaging	1	neutral	0,22	neutral	-0,37	deleterious	-5,54	deleterious	-7,62	high_impact	4,24	damaging	0,57	damaging	0,07	deleterious	3,71	23,3	0,06	0,35	disease	0,69	disease	0,81	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,83	low_impact	-3,43	medium_impact	-0,12	high_impact	2,78	0,33	0,8	0,87	6,92	P	0,64	P	0,94	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10255	10255	A	G	MI.15389	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	197	66	D	G	gAt/gGt	7,3	1	0	probably_damaging	1	neutral	0,14	neutral	-0,38	deleterious	-6,03	deleterious	-6,69	high_impact	4,93	damaging	0,47	damaging	0,08	deleterious	4,07	23,7	0,07	0,35	disease	0,69	disease	0,87	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,81	low_impact	-3,43	medium_impact	-0,25	high_impact	3,41	0,33	0,8	0,87	6,92	P	0,69	P	0,98	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8409	8409	C	G	MI.1539	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	44	15	P	R	cCc/cGc	-1,26	0	0	probably_damaging	1	neutral	0,11	neutral	1,99	neutral	-0,88	neutral	-1,51	low_impact	1,36	neutral	0,99	neutral	0,44	deleterious	2,3	18,2	0,37202141	0,85	disease	0,55	neutral	0,28	disease	0,64	neutral	0,14	7	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	-0,22	medium_impact	0,07	0,72	0,85	8,82	7,31	N	0,55	P	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10255	10255	A	T	MI.15390	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	197	66	D	V	gAt/gTt	7,3	1	0	probably_damaging	1	neutral	0,69	neutral	-0,41	deleterious	-7,53	deleterious	-8,62	high_impact	4,93	damaging	0,43	damaging	0,05	deleterious	3,78	23,4	0,03	0,35	disease	0,84	disease	0,91	disease	0,77	disease	0,65	3	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,85	low_impact	-3,43	medium_impact	0,38	high_impact	3,41	0,16	0,8	0,87	6,92	P	0,71	P	0,99	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10256	10256	T	A	MI.15391	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	198	66	D	E	gaT/gaA	8,69	1	0	probably_damaging	1	neutral	0,22	neutral	-0,29	deleterious	-4,14	deleterious	-3,81	high_impact	3,78	damaging	0,54	damaging	0,09	deleterious	4,1	23,7	0,15	0,4	disease	0,51	disease	0,81	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,79	low_impact	-3,43	medium_impact	-0,12	high_impact	2,36	0,48	0,8	0,87	6,92	P	0,64	P	0,93	polymorphism	0,97	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10256	10256	T	G	MI.15392	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	198	66	D	E	gaT/gaG	8,69	1	0	probably_damaging	1	neutral	0,22	neutral	-0,29	deleterious	-4,14	deleterious	-3,81	high_impact	3,78	damaging	0,54	damaging	0,09	deleterious	3,92	23,5	0,15	0,4	disease	0,51	disease	0,81	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,79	low_impact	-3,43	medium_impact	-0,12	high_impact	2,36	0,48	0,8	0,87	6,92	P	0,64	P	0,93	polymorphism	0,97	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10257	10257	C	A	MI.15393	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	199	67	L	M	Cta/Ata	-0,1	0	0	probably_damaging	1	neutral	0,23	neutral	0,64	neutral	-2,71	neutral	-1,94	medium_impact	3,26	damaging	0,49	damaging	0,02	deleterious	3,89	23,5	0,2	0,45	neutral	0,46	disease	0,52	disease	0,6	disease	0,61	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,72	low_impact	-3,43	medium_impact	-0,1	medium_impact	1,88	0,77	0,85	NA	NA	N	0,39	N	0,91	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10257	10257	C	G	MI.15394	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	199	67	L	V	Cta/Gta	-0,1	0	0	probably_damaging	1	neutral	0,89	neutral	1,01	neutral	1,11	deleterious	-2,9	low_impact	1,34	damaging	0,44	damaging	0,02	deleterious	3,38	23	0,26	0,45	neutral	0,21	neutral	0,33	neutral	0,36	neutral	0,4	2	deleterious	1	neutral	0,45	neutral	-2	deleterious	0,7	low_impact	-3,43	medium_impact	0,69	medium_impact	0,12	0,63	0,8	NA	NA	N	0,36	N	0,89	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10258	10258	T	A	MI.15395	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	200	67	L	Q	cTa/cAa	-0,33	0	0	probably_damaging	1	neutral	0,14	neutral	0,58	deleterious	-4,94	deleterious	-5,81	high_impact	4,46	damaging	0,46	damaging	0,02	deleterious	4,02	23,6	0,04	0,35	disease	0,8	disease	0,76	disease	0,62	disease	0,63	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,81	low_impact	-3,43	medium_impact	-0,25	high_impact	2,98	0,3	0,8	NA	NA	N	0,41	N	0,97	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10258	10258	T	C	MI.15396	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	200	67	L	P	cTa/cCa	-0,33	0	0	probably_damaging	1	neutral	0,1	neutral	0,58	deleterious	-4,8	deleterious	-6,79	high_impact	3,77	damaging	0,44	damaging	0,01	deleterious	3,91	23,5	0,03	0,35	disease	0,84	disease	0,8	disease	0,72	disease	0,65	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	-0,34	high_impact	2,35	0,24	0,8	NA	NA	N	0,42	N	0,99	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10258	10258	T	G	MI.15397	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	200	67	L	R	cTa/cGa	-0,33	0	0	probably_damaging	1	neutral	0,16	neutral	0,58	deleterious	-4,84	deleterious	-5,81	high_impact	4,46	damaging	0,52	damaging	0,02	deleterious	4,21	23,9	0,02	0,35	disease	0,8	disease	0,88	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,87	low_impact	-3,43	medium_impact	-0,21	high_impact	2,98	0,2	0,8	NA	NA	N	0,42	N	1	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10260	10260	G	A	MI.15398	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	202	68	E	K	Gaa/Aaa	-0,1	0,75	0	benign	0,18	neutral	0,29	neutral	-0,07	deleterious	-5,14	deleterious	-3,86	high_impact	4,93	damaging	0,37	damaging	0,03	deleterious	4,47	24,2	0,06	0,35	disease	0,63	disease	0,87	disease	0,84	disease	0,73	5	neutral	0,66	deleterious	0,56	neutral	-2	deleterious	0,54	medium_impact	-0,12	medium_impact	-0,03	high_impact	3,41	0,7	0,85	3,48	7,62	P	0,7	P	0,99	polymorphism	1	0,84	rs28655588	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10260	10260	G	C	MI.15399	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	202	68	E	Q	Gaa/Caa	-0,1	0,75	0	probably_damaging	0,91	neutral	0,29	neutral	-0,08	deleterious	-5,22	deleterious	-2,9	high_impact	4,93	damaging	0,39	damaging	0,03	deleterious	3,3	22,9	0,11	0,4	disease	0,68	disease	0,74	disease	0,75	disease	0,69	4	neutral	0,93	neutral	0,19	deleterious	2	deleterious	0,78	low_impact	-1,62	medium_impact	-0,03	high_impact	3,41	0,55	0,8	3,48	7,62	P	0,69	P	0,9	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8598	8598	T	G	MI.154	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	72	24	I	M	atT/atG	3,83	0,43	0	probably_damaging	1	neutral	0,35	neutral	3,96	neutral	-2,76	neutral	-1,44	neutral_impact	-0,32	neutral	0,87	neutral	0,96	neutral	1,69	14,33	0,5	0,65	disease	0,56	neutral	0,13	neutral	0,27	neutral	0,29	4	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,14	low_impact	-1,37	0,7	0,9	18,14	17,22	N	0,45	N	0,63	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8411	8411	A	G	MI.1540	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	46	16	M	V	Ata/Gta	-6,12	0	0	possibly_damaging	0,75	neutral	0,52	neutral	1,94	neutral	1,33	deleterious	-3,28	medium_impact	2	neutral	1	neutral	0,68	deleterious	2,35	18,52	0,5726291	0,85	neutral	0,4	neutral	0,4	disease	0,64	neutral	0,18	6	neutral	0,73	neutral	0,39	NA	0	deleterious	0,48	low_impact	-1,21	medium_impact	0,31	medium_impact	0,62	0,53	0,85	NA	NA	N	0,39	N	0,61	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	A8411G	Severe mitochondrial disorder	+	-	Reported	1
chrM	10261	10261	A	G	MI.15400	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	203	68	E	G	gAa/gGa	6,14	1	0	probably_damaging	0,94	neutral	0,32	neutral	-0,08	deleterious	-5,26	deleterious	-6,76	high_impact	4,59	damaging	0,38	damaging	0,05	deleterious	4,03	23,7	0,06	0,35	disease	0,68	disease	0,75	disease	0,77	disease	0,69	4	neutral	0,94	neutral	0,19	deleterious	2	deleterious	0,8	low_impact	-1,8	medium_impact	0,01	high_impact	3,1	0,1	0,8	3,48	7,62	P	0,74	P	0,61	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10261	10261	A	C	MI.15401	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	203	68	E	A	gAa/gCa	6,14	1	0	possibly_damaging	0,81	neutral	0,52	neutral	-0,08	deleterious	-5,32	deleterious	-5,79	high_impact	4,93	damaging	0,45	damaging	0,07	deleterious	3,51	23,1	0,06	0,35	disease	0,66	disease	0,7	disease	0,75	disease	0,69	4	neutral	0,79	neutral	0,36	deleterious	1	deleterious	0,78	low_impact	-1,29	medium_impact	0,21	high_impact	3,41	0,27	0,8	3,48	7,62	P	0,69	P	0,76	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10261	10261	A	T	MI.15402	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	203	68	E	V	gAa/gTa	6,14	1	0	probably_damaging	0,95	neutral	0,58	neutral	-0,11	deleterious	-6,94	deleterious	-6,77	high_impact	4,93	damaging	0,38	damaging	0,04	deleterious	4	23,6	0,05	0,35	disease	0,8	disease	0,85	disease	0,81	disease	0,68	4	neutral	0,95	neutral	0,32	deleterious	2	deleterious	0,86	low_impact	-1,87	medium_impact	0,27	high_impact	3,41	0,21	0,8	3,48	7,62	P	0,76	P	0,84	polymorphism	1	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10262	10262	A	T	MI.15403	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	204	68	E	D	gaA/gaT	6,84	1	0	possibly_damaging	0,84	neutral	0,33	neutral	0,12	neutral	-2,71	deleterious	-2,9	high_impact	4,04	damaging	0,41	damaging	0,03	deleterious	3,87	23,5	0,15	0,4	neutral	0,5	disease	0,73	disease	0,76	disease	0,68	4	neutral	0,86	neutral	0,25	deleterious	1	deleterious	0,75	low_impact	-1,37	medium_impact	0,02	high_impact	2,6	0,5	0,8	3,48	7,62	P	0,8	P	0,86	polymorphism	0,98	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10262	10262	A	C	MI.15404	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	204	68	E	D	gaA/gaC	6,84	1	0	possibly_damaging	0,84	neutral	0,33	neutral	0,12	neutral	-2,71	deleterious	-2,9	high_impact	4,04	damaging	0,41	damaging	0,03	deleterious	3,72	23,3	0,15	0,4	neutral	0,5	disease	0,73	disease	0,76	disease	0,68	4	neutral	0,86	neutral	0,25	deleterious	1	deleterious	0,75	low_impact	-1,37	medium_impact	0,02	high_impact	2,6	0,5	0,8	3,48	7,62	P	0,79	P	0,86	polymorphism	0,98	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10263	10263	A	C	MI.15405	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	205	69	I	L	Att/Ctt	3,37	1	0	probably_damaging	0,99	neutral	0,67	neutral	0,92	neutral	-0,54	neutral	-1,85	medium_impact	2,86	damaging	0,5	damaging	0,06	deleterious	3,55	23,1	0,2	0,45	neutral	0,34	disease	0,71	disease	0,56	disease	0,63	3	deleterious	0,99	neutral	0,34	deleterious	1	deleterious	0,72	low_impact	-2,52	medium_impact	0,36	medium_impact	1,51	0,45	0,8	NA	NA	N	0,5	N	0,85	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10263	10263	A	T	MI.15406	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	205	69	I	F	Att/Ttt	3,37	1	0	probably_damaging	1	neutral	0,71	neutral	0,8	neutral	-2	deleterious	-3,79	high_impact	4,66	damaging	0,49	damaging	0,06	deleterious	3,54	23,1	0,1	0,4	disease	0,66	disease	0,77	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,79	low_impact	-3,43	medium_impact	0,41	high_impact	3,16	0,47	0,8	NA	NA	P	0,59	P	0,97	polymorphism	1	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10263	10263	A	G	MI.15407	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	205	69	I	V	Att/Gtt	3,37	1	0	probably_damaging	0,99	neutral	0,56	neutral	0,98	neutral	-0,1	neutral	-0,94	low_impact	1,75	damaging	0,56	damaging	0,1	deleterious	2,81	21,4	0,28	0,45	neutral	0,28	neutral	0,41	disease	0,53	neutral	0,42	2	deleterious	0,99	neutral	0,29	neutral	-2	deleterious	0,65	low_impact	-2,52	medium_impact	0,25	medium_impact	0,5	0,32	0,8	NA	NA	N	0,44	N	0,79	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10264	10264	T	C	MI.15408	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	206	69	I	T	aTt/aCt	8,69	1	0	probably_damaging	1	neutral	0,41	neutral	0,83	neutral	-1,48	deleterious	-4,74	medium_impact	2,7	damaging	0,51	damaging	0,07	deleterious	3,41	23	0,07	0,35	disease	0,66	disease	0,67	disease	0,61	disease	0,64	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-3,43	medium_impact	0,1	medium_impact	1,37	0,32	0,8	NA	NA	P	0,57	P	0,99	polymorphism	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10264	10264	T	G	MI.15409	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	206	69	I	S	aTt/aGt	8,69	1	0	probably_damaging	1	neutral	0,41	neutral	0,8	neutral	-2,07	deleterious	-5,68	high_impact	3,69	damaging	0,54	damaging	0,08	deleterious	4,29	24	0,04	0,35	disease	0,74	disease	0,81	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,8	low_impact	-3,43	medium_impact	0,1	high_impact	2,28	0,27	0,8	NA	NA	P	0,57	P	0,96	polymorphism	1	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8411	8411	A	T	MI.1541	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	46	16	M	L	Ata/Tta	-6,12	0	0	possibly_damaging	0,66	neutral	0,64	neutral	2,05	neutral	1,38	deleterious	-2,55	medium_impact	2,63	neutral	0,97	neutral	0,4	deleterious	3	22,2	0,54043948	0,85	neutral	0,37	neutral	0,49	disease	0,7	neutral	0,45	1	neutral	0,59	deleterious	0,49	NA	0	deleterious	0,43	low_impact	-1,03	medium_impact	0,43	medium_impact	1,16	0,5	0,85	NA	NA	N	0,36	N	0,58	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10264	10264	T	A	MI.15410	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	206	69	I	N	aTt/aAt	8,69	1	0	probably_damaging	1	neutral	0,31	neutral	0,75	deleterious	-3,7	deleterious	-6,66	high_impact	4,66	damaging	0,48	damaging	0,06	deleterious	4,52	24,3	0,07	0,35	disease	0,84	disease	0,85	disease	0,64	disease	0,63	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,81	low_impact	-3,43	medium_impact	0	high_impact	3,16	0,33	0,8	NA	NA	P	0,65	P	0,99	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10265	10265	T	A	MI.15411	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	207	69	I	M	atT/atA	5,68	1	0	probably_damaging	1	neutral	0,23	neutral	0,84	neutral	-1,3	deleterious	-2,71	medium_impact	3,38	neutral	0,61	damaging	0,08	deleterious	3,71	23,3	0,13	0,4	disease	0,64	disease	0,67	disease	0,54	disease	0,61	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,73	low_impact	-3,43	medium_impact	-0,1	medium_impact	1,99	0,43	0,8	NA	NA	P	0,64	P	0,78	polymorphism	0,99	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10265	10265	T	G	MI.15412	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	207	69	I	M	atT/atG	5,68	1	0	probably_damaging	1	neutral	0,23	neutral	0,84	neutral	-1,3	deleterious	-2,71	medium_impact	3,38	neutral	0,61	damaging	0,08	deleterious	3,42	23	0,13	0,4	disease	0,64	disease	0,67	disease	0,54	disease	0,61	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,73	low_impact	-3,43	medium_impact	-0,1	medium_impact	1,99	0,43	0,8	NA	NA	P	0,63	P	0,78	polymorphism	0,99	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10266	10266	G	C	MI.15413	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	208	70	A	P	Gcc/Ccc	-4,73	0	0	probably_damaging	1	neutral	0,19	neutral	0,86	deleterious	-3,71	deleterious	-4,75	high_impact	4,12	damaging	0,52	damaging	0,05	deleterious	3,79	23,4	0,04	0,35	disease	0,67	disease	0,85	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-3,43	medium_impact	-0,16	high_impact	2,67	0,51	0,8	NA	NA	N	0,34	N	0,96	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10266	10266	G	T	MI.15414	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	208	70	A	S	Gcc/Tcc	-4,73	0	0	probably_damaging	1	neutral	0,29	neutral	0,95	neutral	-2,09	deleterious	-2,83	medium_impact	2,38	damaging	0,58	damaging	0,05	deleterious	3,7	23,3	0,25	0,45	neutral	0,25	disease	0,7	disease	0,57	disease	0,53	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,72	low_impact	-3,43	medium_impact	-0,03	medium_impact	1,07	0,35	0,8	NA	NA	N	0,25	N	0,98	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10266	10266	G	A	MI.15415	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	208	70	A	T	Gcc/Acc	-4,73	0	0	probably_damaging	1	neutral	0,34	neutral	0,94	neutral	-1,65	deleterious	-3,67	medium_impact	2,44	damaging	0,52	neutral	0,32	deleterious	4,21	23,9	0,16	0,45	neutral	0,45	disease	0,6	neutral	0,38	neutral	0,17	7	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,73	low_impact	-3,43	medium_impact	0,03	medium_impact	1,13	0,72	0,85	NA	NA	N	0,41	N	0,93	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10267	10267	C	A	MI.15416	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	209	70	A	D	gCc/gAc	2,9	0,99	0	probably_damaging	1	neutral	0,29	neutral	0,85	deleterious	-4,07	deleterious	-5,69	high_impact	4,46	damaging	0,59	damaging	0,03	deleterious	4,5	24,3	0,03	0,35	disease	0,69	disease	0,88	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,8	low_impact	-3,43	medium_impact	-0,03	high_impact	2,98	0,26	0,8	NA	NA	P	0,57	P	0,96	polymorphism	1	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10267	10267	C	T	MI.15417	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	209	70	A	V	gCc/gTc	2,9	0,99	0	probably_damaging	1	neutral	0,73	neutral	1,11	neutral	1,1	deleterious	-3,69	low_impact	1,6	damaging	0,5	damaging	0,06	deleterious	4,48	24,2	0,17	0,45	disease	0,57	disease	0,67	neutral	0,5	neutral	0,21	6	deleterious	1	neutral	0,37	neutral	-2	deleterious	0,74	low_impact	-3,43	medium_impact	0,43	medium_impact	0,36	0,68	0,85	NA	NA	N	0,44	N	0,79	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10267	10267	C	G	MI.15418	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	209	70	A	G	gCc/gGc	2,9	0,99	0	probably_damaging	1	neutral	0,2	neutral	0,86	deleterious	-3,29	deleterious	-3,83	high_impact	4,46	damaging	0,54	damaging	0,08	deleterious	4,01	23,6	0,21	0,45	neutral	0,49	disease	0,69	disease	0,58	disease	0,62	2	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,73	low_impact	-3,43	medium_impact	-0,14	high_impact	2,98	0,63	0,8	NA	NA	P	0,56	P	0,85	polymorphism	1	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10269	10269	C	G	MI.15419	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	211	71	L	V	Ctc/Gtc	-4,96	0	0	probably_damaging	1	neutral	0,37	neutral	0,56	neutral	-1,44	deleterious	-2,73	high_impact	3,9	damaging	0,41	damaging	0,05	deleterious	3,45	23	0,24	0,45	neutral	0,35	neutral	0,46	disease	0,63	neutral	0,47	1	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,7	low_impact	-3,43	medium_impact	0,06	high_impact	2,47	0,46	0,8	NA	NA	N	0,49	N	0,89	polymorphism	1	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8411	8411	A	C	MI.1542	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	46	16	M	L	Ata/Cta	-6,12	0	0	possibly_damaging	0,66	neutral	0,64	neutral	2,05	neutral	1,38	deleterious	-2,55	medium_impact	2,63	neutral	0,97	neutral	0,4	deleterious	2,86	21,7	0,54043948	0,85	neutral	0,37	neutral	0,49	disease	0,7	neutral	0,45	1	neutral	0,59	deleterious	0,49	NA	0	deleterious	0,43	low_impact	-1,03	medium_impact	0,43	medium_impact	1,16	0,5	0,85	NA	NA	N	0,29	N	0,58	polymorphism	1	0,31	rs878942289	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10269	10269	C	A	MI.15420	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	211	71	L	I	Ctc/Atc	-4,96	0	0	probably_damaging	1	neutral	0,72	neutral	0,6	neutral	-1,52	neutral	-1,77	medium_impact	2,54	neutral	0,61	neutral	0,48	deleterious	4,06	23,7	0,2	0,45	neutral	0,24	neutral	0,5	neutral	0,41	neutral	0,17	7	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,69	low_impact	-3,43	medium_impact	0,42	medium_impact	1,22	0,57	0,8	NA	NA	N	0,31	N	0,86	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10269	10269	C	T	MI.15421	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	211	71	L	F	Ctc/Ttc	-4,96	0	0	probably_damaging	1	neutral	0,27	neutral	0,69	neutral	1,88	deleterious	-3,79	low_impact	1,89	damaging	0,44	damaging	0,05	deleterious	3,98	23,6	0,21	0,45	disease	0,53	disease	0,58	disease	0,6	disease	0,62	2	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,74	low_impact	-3,43	medium_impact	-0,05	medium_impact	0,62	0,44	0,8	NA	NA	N	0,38	N	0,99	polymorphism	1	0,51	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	10270	10270	T	C	MI.15422	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	212	71	L	P	cTc/cCc	1,05	0,43	0	probably_damaging	1	neutral	0,16	neutral	0,46	deleterious	-4,27	deleterious	-6,7	high_impact	4,6	damaging	0,4	damaging	0,04	deleterious	3,91	23,5	0,02	0,35	disease	0,86	disease	0,75	disease	0,74	disease	0,66	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-3,43	medium_impact	-0,21	high_impact	3,11	0,23	0,8	NA	NA	P	0,6	P	0,99	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10270	10270	T	A	MI.15423	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	212	71	L	H	cTc/cAc	1,05	0,43	0	probably_damaging	1	neutral	0,16	neutral	0,46	deleterious	-3,51	deleterious	-6,69	high_impact	4,6	damaging	0,45	damaging	0,04	deleterious	4,13	23,8	0,04	0,35	disease	0,89	disease	0,76	disease	0,71	disease	0,65	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,8	low_impact	-3,43	medium_impact	-0,21	high_impact	3,11	0,28	0,8	NA	NA	P	0,48	N	0,97	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10270	10270	T	G	MI.15424	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	212	71	L	R	cTc/cGc	1,05	0,43	0	probably_damaging	1	neutral	0,19	neutral	0,47	deleterious	-3,6	deleterious	-5,76	high_impact	4,6	damaging	0,46	damaging	0,03	deleterious	4,2	23,9	0,02	0,35	disease	0,82	disease	0,84	disease	0,75	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,43	medium_impact	-0,16	high_impact	3,11	0,17	0,8	NA	NA	P	0,53	P	1	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10272	10272	C	T	MI.15425	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	214	72	L	F	Ctt/Ttt	-20	0	0	probably_damaging	1	neutral	0,19	neutral	0,22	deleterious	-3,17	deleterious	-3,87	medium_impact	3,03	damaging	0,45	damaging	0,01	deleterious	3,94	23,5	0,14	0,4	disease	0,53	disease	0,52	disease	0,69	disease	0,65	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,75	low_impact	-3,43	medium_impact	-0,16	medium_impact	1,67	0,4	0,8	1,74	6,76	N	0,34	N	0,99	polymorphism	1	0,56	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	10272	10272	C	G	MI.15426	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	214	72	L	V	Ctt/Gtt	-20	0	0	probably_damaging	1	neutral	0,13	neutral	0,18	deleterious	-3,71	deleterious	-2,9	medium_impact	3,38	damaging	0,45	damaging	0,03	deleterious	3,43	23	0,22	0,45	neutral	0,36	neutral	0,4	disease	0,7	neutral	0,46	1	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,71	low_impact	-3,43	medium_impact	-0,27	medium_impact	1,99	0,53	0,8	1,74	6,76	N	0,37	N	0,89	polymorphism	1	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10272	10272	C	A	MI.15427	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	214	72	L	I	Ctt/Att	-20	0	0	probably_damaging	1	neutral	0,32	neutral	0,4	neutral	-1,89	neutral	-1,94	medium_impact	2,32	damaging	0,45	damaging	0,04	deleterious	4,15	23,8	0,23	0,45	neutral	0,25	neutral	0,34	neutral	0,46	neutral	0,39	2	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,7	low_impact	-3,43	medium_impact	0,01	medium_impact	1,02	0,48	0,8	1,74	6,76	N	0,38	N	0,86	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10273	10273	T	A	MI.15428	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	215	72	L	H	cTt/cAt	1,29	0,72	0	probably_damaging	1	deleterious	0,04	neutral	0,09	deleterious	-7,8	deleterious	-6,78	high_impact	4,73	damaging	0,47	damaging	0,01	deleterious	4,06	23,7	0,05	0,35	disease	0,89	disease	0,72	disease	0,76	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-3,43	medium_impact	-0,58	high_impact	3,23	0,32	0,8	1,74	6,76	P	0,56	P	0,97	polymorphism	1	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10273	10273	T	C	MI.15429	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	215	72	L	P	cTt/cCt	1,29	0,72	0	probably_damaging	1	neutral	0,19	neutral	0,1	deleterious	-7,49	deleterious	-6,79	high_impact	4,73	damaging	0,41	damaging	0,02	deleterious	3,76	23,4	0,03	0,35	disease	0,86	disease	0,72	disease	0,79	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,43	medium_impact	-0,16	high_impact	3,23	0,31	0,8	1,74	6,76	P	0,67	P	0,99	polymorphism	1	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8412	8412	T	A	MI.1543	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	47	16	M	K	aTa/aAa	0,59	0	0	possibly_damaging	0,88	neutral	0,29	neutral	1,8	neutral	-0,46	deleterious	-5,2	medium_impact	3,33	neutral	0,99	neutral	0,31	deleterious	3,72	23,3	0,32107757	0,85	disease	0,53	disease	0,66	disease	0,79	disease	0,64	3	neutral	0,9	neutral	0,21	NA	0	deleterious	0,73	low_impact	-1,58	medium_impact	0,07	medium_impact	1,76	0,42	0,85	NA	NA	N	0,52	P	0,79	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10273	10273	T	G	MI.15430	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	215	72	L	R	cTt/cGt	1,29	0,72	0	probably_damaging	1	deleterious	0,03	neutral	0,1	deleterious	-7,09	deleterious	-5,81	high_impact	4,73	damaging	0,5	damaging	0,02	deleterious	4,11	23,7	0,03	0,35	disease	0,82	disease	0,8	disease	0,8	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-3,43	medium_impact	-0,65	high_impact	3,23	0,28	0,8	1,74	6,76	P	0,58	P	1	polymorphism	1	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10275	10275	T	G	MI.15431	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	217	73	L	V	Tta/Gta	-14,22	0	0	possibly_damaging	0,87	neutral	0,11	neutral	0,69	neutral	-0,87	deleterious	-2,8	medium_impact	2,89	damaging	0,57	damaging	0,03	deleterious	3,41	23	0,26	0,45	disease	0,5	neutral	0,4	disease	0,63	neutral	0,39	2	neutral	0,95	neutral	0,12	NA	0	deleterious	0,71	low_impact	-1,46	medium_impact	-0,31	medium_impact	1,54	0,57	0,8	NA	NA	N	0,31	N	0,89	polymorphism	1	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10275	10275	T	A	MI.15432	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	217	73	L	M	Tta/Ata	-14,22	0	0	probably_damaging	0,99	neutral	0,05	neutral	0,64	neutral	-1,9	neutral	-1,87	medium_impact	2,33	neutral	0,65	damaging	0,04	deleterious	3,59	23,2	0,22	0,45	disease	0,59	neutral	0,39	neutral	0,41	disease	0,54	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,72	low_impact	-2,52	medium_impact	-0,52	medium_impact	1,03	0,42	0,8	NA	NA	N	0,32	N	0,91	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10276	10276	T	G	MI.15433	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	218	73	L	W	tTa/tGa	-0,1	0	0	probably_damaging	1	deleterious	0,03	neutral	0,58	neutral	-2,42	deleterious	-5,65	high_impact	3,87	damaging	0,56	damaging	0,02	deleterious	3,64	23,2	0,05	0,35	disease	0,91	disease	0,64	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-3,43	medium_impact	-0,65	high_impact	2,44	0,26	0,8	NA	NA	N	0,32	N	0,98	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10276	10276	T	C	MI.15434	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	218	73	L	S	tTa/tCa	-0,1	0	0	probably_damaging	0,96	neutral	0,11	neutral	0,61	neutral	-2,11	deleterious	-5,59	high_impact	3,72	damaging	0,53	damaging	0,04	deleterious	3,67	23,3	0,04	0,35	disease	0,8	disease	0,6	disease	0,65	disease	0,67	3	deleterious	0,98	neutral	0,08	deleterious	2	deleterious	0,8	low_impact	-1,96	medium_impact	-0,31	high_impact	2,3	0,28	0,8	NA	NA	N	0,34	N	0,97	polymorphism	1	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10277	10277	A	C	MI.15435	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	219	73	L	F	ttA/ttC	7,53	0,96	0	probably_damaging	0,99	neutral	0,33	neutral	0,78	neutral	1,56	deleterious	-3,77	low_impact	1,07	damaging	0,56	damaging	0,02	deleterious	3,44	23	0,22	0,45	disease	0,61	neutral	0,43	neutral	0,42	disease	0,52	0	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,76	low_impact	-2,52	medium_impact	0,02	medium_impact	-0,13	0,38	0,8	NA	NA	N	0,48	N	0,99	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10277	10277	A	T	MI.15436	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	219	73	L	F	ttA/ttT	7,53	0,96	0	probably_damaging	0,99	neutral	0,33	neutral	0,78	neutral	1,56	deleterious	-3,77	low_impact	1,07	damaging	0,56	damaging	0,02	deleterious	3,54	23,1	0,22	0,45	disease	0,61	neutral	0,43	neutral	0,42	disease	0,52	0	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,76	low_impact	-2,52	medium_impact	0,02	medium_impact	-0,13	0,38	0,8	NA	NA	N	0,49	N	0,99	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10278	10278	C	A	MI.15437	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	220	74	P	T	Ccc/Acc	-20	0	0	possibly_damaging	0,81	neutral	0,19	neutral	0,45	deleterious	-3,49	deleterious	-7,66	high_impact	3,92	damaging	0,54	neutral	0,31	deleterious	3,67	23,3	0,05	0,35	disease	0,97	disease	0,76	disease	0,71	disease	0,69	4	neutral	0,89	neutral	0,19	deleterious	1	deleterious	0,78	low_impact	-1,29	medium_impact	-0,16	high_impact	2,49	0,55	0,8	8,7	10,6	N	0,35	N	0,71	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10278	10278	C	G	MI.15438	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	220	74	P	A	Ccc/Gcc	-20	0	0	possibly_damaging	0,73	neutral	0,27	neutral	0,51	neutral	-2,62	deleterious	-7,66	medium_impact	3,44	damaging	0,59	neutral	0,39	deleterious	3,06	22,4	0,07	0,35	disease	0,95	disease	0,62	disease	0,7	disease	0,74	5	neutral	0,81	neutral	0,27	NA	0	deleterious	0,74	low_impact	-1,11	medium_impact	-0,05	high_impact	2,05	0,65	0,8	8,7	10,6	N	0,37	N	0,6	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10278	10278	C	T	MI.15439	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	220	74	P	S	Ccc/Tcc	-20	0	0	benign	0,18	neutral	0,29	neutral	0,49	neutral	-2,87	deleterious	-7,65	high_impact	3,51	damaging	0,54	neutral	0,4	deleterious	3,86	23,5	0,06	0,35	disease	0,96	disease	0,77	disease	0,65	disease	0,69	4	neutral	0,66	deleterious	0,56	neutral	-2	neutral	0,41	medium_impact	-0,12	medium_impact	-0,03	high_impact	2,11	0,15	0,8	8,7	10,6	N	0,36	N	0,32	polymorphism	1	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8412	8412	T	C	MI.1544	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	47	16	M	T	aTa/aCa	0,59	0	0	possibly_damaging	0,88	neutral	0,44	neutral	1,89	neutral	1,84	deleterious	-4,63	low_impact	1,05	neutral	1	neutral	0,94	neutral	1,48	13,23	0,6294906	0,85	neutral	0,45	neutral	0,28	disease	0,62	neutral	0,09	8	neutral	0,87	neutral	0,28	neutral	-3	deleterious	0,66	low_impact	-1,58	medium_impact	0,23	medium_impact	-0,2	0,42	0,85	NA	NA	N	0,49	N	0,71	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10279	10279	C	A	MI.15440	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	221	74	P	H	cCc/cAc	5,45	1	0	probably_damaging	0,99	neutral	0,23	neutral	0,41	deleterious	-5,03	deleterious	-8,61	high_impact	4,89	damaging	0,51	damaging	0,23	deleterious	4,11	23,7	0,03	0,35	disease	0,99	disease	0,85	disease	0,79	disease	0,78	6	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-2,52	medium_impact	-0,1	high_impact	3,38	0,29	0,8	8,7	10,6	P	0,67	P	0,87	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10279	10279	C	G	MI.15441	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	221	74	P	R	cCc/cGc	5,45	1	0	probably_damaging	0,97	neutral	0,14	neutral	0,43	deleterious	-4	deleterious	-8,61	high_impact	4,89	damaging	0,56	damaging	0,28	deleterious	3,58	23,2	0,03	0,35	disease	0,98	disease	0,88	disease	0,79	disease	0,74	5	deleterious	0,98	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-2,08	medium_impact	-0,25	high_impact	3,38	0,33	0,8	8,7	10,6	P	0,7	P	0,9	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10279	10279	C	T	MI.15442	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	221	74	P	L	cCc/cTc	5,45	1	0	probably_damaging	0,94	neutral	1	neutral	0,44	deleterious	-3,78	deleterious	-9,54	high_impact	4,2	damaging	0,52	neutral	0,38	deleterious	4,32	24	0,04	0,35	disease	0,98	disease	0,86	disease	0,68	disease	0,69	4	neutral	0,93	deleterious	0,53	deleterious	2	deleterious	0,85	low_impact	-1,8	high_impact	1,85	high_impact	2,74	0,43	0,8	8,7	10,6	P	0,59	P	0,91	polymorphism	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10281	10281	C	A	MI.15443	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	223	75	L	M	Cta/Ata	-8,89	0	0	probably_damaging	0,98	neutral	0,24	neutral	0,89	neutral	-1,2	neutral	-1,74	medium_impact	2,06	neutral	0,79	neutral	0,52	deleterious	3,67	23,3	0,3	0,45	neutral	0,31	neutral	0,3	neutral	0,31	neutral	0,44	1	deleterious	0,98	neutral	0,13	deleterious	1	deleterious	0,67	low_impact	-2,24	medium_impact	-0,09	medium_impact	0,78	0,48	0,8	4,35	6,92	N	0,39	N	0,91	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10281	10281	C	G	MI.15444	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	223	75	L	V	Cta/Gta	-8,89	0	0	benign	0,18	neutral	0,54	neutral	0,95	neutral	-0,4	neutral	-2,31	medium_impact	2,56	neutral	0,76	neutral	0,44	neutral	1,48	13,22	0,27	0,45	neutral	0,41	neutral	0,34	disease	0,6	neutral	0,48	0	neutral	0,35	deleterious	0,68	neutral	-3	neutral	0,22	medium_impact	-0,12	medium_impact	0,23	medium_impact	1,24	0,52	0,8	4,35	6,92	N	0,3	N	0,89	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10282	10282	T	G	MI.15445	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	224	75	L	R	cTa/cGa	0,13	0	0	probably_damaging	0,98	neutral	0,35	neutral	0,82	neutral	-2,94	deleterious	-5,51	high_impact	4,01	neutral	0,67	damaging	0,25	deleterious	4,12	23,8	0,04	0,35	disease	0,83	disease	0,79	disease	0,71	disease	0,67	3	neutral	0,98	neutral	0,19	deleterious	2	deleterious	0,86	low_impact	-2,24	medium_impact	0,04	high_impact	2,57	0,19	0,8	4,35	6,92	N	0,34	N	1	polymorphism	1	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10282	10282	T	A	MI.15446	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	224	75	L	Q	cTa/cAa	0,13	0	0	probably_damaging	0,98	neutral	0,29	neutral	0,82	deleterious	-3,11	deleterious	-5,48	high_impact	3,66	neutral	0,72	neutral	0,29	deleterious	4	23,6	0,06	0,35	disease	0,81	disease	0,69	disease	0,59	disease	0,65	3	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,8	low_impact	-2,24	medium_impact	-0,03	high_impact	2,25	0,21	0,8	4,35	6,92	N	0,34	N	0,97	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10282	10282	T	C	MI.15447	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	224	75	L	P	cTa/cCa	0,13	0	0	probably_damaging	0,98	neutral	0,38	neutral	0,81	deleterious	-3,53	deleterious	-6,37	medium_impact	2,77	neutral	0,62	damaging	0,25	deleterious	3,84	23,4	0,04	0,35	disease	0,86	disease	0,78	disease	0,69	disease	0,66	3	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,85	low_impact	-2,24	medium_impact	0,07	medium_impact	1,43	0,2	0,8	4,35	6,92	N	0,25	N	0,99	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10284	10284	C	G	MI.15448	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	226	76	P	A	Cca/Gca	-12,37	0	0	probably_damaging	1	neutral	0,54	neutral	1,18	neutral	1,53	deleterious	-7,41	medium_impact	2,83	neutral	0,65	damaging	0,12	deleterious	3,05	22,4	0,19	0,45	neutral	0,29	neutral	0,44	disease	0,55	neutral	0,41	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,7	low_impact	-3,43	medium_impact	0,23	medium_impact	1,49	0,6	0,8	NA	NA	N	0,34	N	0,81	polymorphism	1	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10284	10284	C	T	MI.15449	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	226	76	P	S	Cca/Tca	-12,37	0	0	probably_damaging	1	neutral	0,45	neutral	0,97	neutral	-0,57	deleterious	-7,41	medium_impact	3,42	neutral	0,65	damaging	0,11	deleterious	3,84	23,4	0,23	0,45	neutral	0,32	disease	0,63	disease	0,64	disease	0,56	1	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,72	low_impact	-3,43	medium_impact	0,14	high_impact	2,03	0,14	0,8	NA	NA	N	0,32	N	0,95	polymorphism	1	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8413	8413	A	T	MI.1545	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	48	16	M	I	atA/atT	1,75	0	0	possibly_damaging	0,82	neutral	0,4	neutral	1,91	neutral	4,18	deleterious	-3,33	medium_impact	2,29	neutral	0,95	neutral	0,52	deleterious	3,08	22,5	0,55484047	0,85	neutral	0,45	neutral	0,31	disease	0,73	neutral	0,17	7	neutral	0,82	neutral	0,29	NA	0	deleterious	0,57	low_impact	-1,38	medium_impact	0,19	medium_impact	0,87	0,63	0,85	NA	NA	N	0,5	N	0,64	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10284	10284	C	A	MI.15450	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	226	76	P	T	Cca/Aca	-12,37	0	0	probably_damaging	1	neutral	0,41	neutral	0,98	neutral	-0,39	deleterious	-7,41	medium_impact	3,06	neutral	0,61	damaging	0,07	deleterious	3,65	23,2	0,14	0,4	neutral	0,37	disease	0,59	disease	0,54	neutral	0,34	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,72	low_impact	-3,43	medium_impact	0,1	medium_impact	1,7	0,58	0,8	NA	NA	N	0,29	N	0,97	polymorphism	1	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10285	10285	C	T	MI.15451	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	227	76	P	L	cCa/cTa	4,52	0,99	0	probably_damaging	1	neutral	0,96	neutral	1,07	neutral	0,79	deleterious	-9,19	medium_impact	2,42	neutral	0,61	damaging	0,06	deleterious	4,32	24	0,13	0,4	neutral	0,4	disease	0,76	disease	0,62	disease	0,58	2	deleterious	1	deleterious	0,48	deleterious	1	deleterious	0,74	low_impact	-3,43	medium_impact	0,96	medium_impact	1,11	0,51	0,8	NA	NA	N	0,36	N	0,97	polymorphism	1	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10285	10285	C	A	MI.15452	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	227	76	P	Q	cCa/cAa	4,52	0,99	0	probably_damaging	1	neutral	0,28	neutral	0,93	neutral	-1,8	deleterious	-7,39	high_impact	3,87	neutral	0,62	damaging	0,06	deleterious	4,18	23,8	0,11	0,4	neutral	0,49	disease	0,76	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,74	low_impact	-3,43	medium_impact	-0,04	high_impact	2,44	0,42	0,8	NA	NA	P	0,57	P	0,9	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10285	10285	C	G	MI.15453	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	227	76	P	R	cCa/cGa	4,52	0,99	0	probably_damaging	1	neutral	0,36	neutral	0,93	neutral	-1,7	deleterious	-8,36	high_impact	4,22	neutral	0,61	damaging	0,06	deleterious	3,51	23,1	0,07	0,35	neutral	0,49	disease	0,79	disease	0,77	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,79	low_impact	-3,43	medium_impact	0,05	high_impact	2,76	0,33	0,8	NA	NA	P	0,65	P	0,73	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10287	10287	T	C	MI.15454	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	229	77	W	R	Tga/Cga	-6,12	0	0	probably_damaging	0,98	neutral	0,35	neutral	1,01	deleterious	-3,5	deleterious	-13,07	high_impact	4,15	damaging	0,58	damaging	0,03	deleterious	3,54	23,1	0,07	0,35	disease	0,62	disease	0,86	disease	0,77	disease	0,75	5	deleterious	0,98	neutral	0,19	deleterious	2	deleterious	0,81	low_impact	-2,24	medium_impact	0,04	high_impact	2,7	0,13	0,8	2,61	6,92	N	0,47	N	0,97	polymorphism	1	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10287	10287	T	G	MI.15455	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	229	77	W	G	Tga/Gga	-6,12	0	0	probably_damaging	0,96	neutral	0,34	neutral	1,03	deleterious	-3,61	deleterious	-11,87	high_impact	4,15	damaging	0,58	damaging	0,06	deleterious	3,91	23,5	0,09	0,35	disease	0,66	disease	0,74	disease	0,73	disease	0,71	4	neutral	0,96	neutral	0,19	deleterious	2	deleterious	0,74	low_impact	-1,96	medium_impact	0,03	high_impact	2,7	0,11	0,8	2,61	6,92	N	0,41	N	0,97	polymorphism	1	0,69	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10288	10288	G	T	MI.15456	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	230	77	W	L	tGa/tTa	7,53	1	0	possibly_damaging	0,63	neutral	0,82	neutral	1,21	neutral	-1,47	deleterious	-12,04	medium_impact	2,52	damaging	0,52	damaging	0,04	deleterious	4,22	23,9	0,12	0,4	neutral	0,23	disease	0,76	disease	0,69	disease	0,52	0	neutral	0,56	deleterious	0,6	NA	0	deleterious	0,59	medium_impact	-0,93	medium_impact	0,56	medium_impact	1,2	0,1	0,8	2,61	6,92	N	0,49	N	0,97	polymorphism	1	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10288	10288	G	C	MI.15457	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	230	77	W	S	tGa/tCa	7,53	1	0	probably_damaging	0,96	neutral	0,46	neutral	1,06	neutral	-2,61	deleterious	-12,99	medium_impact	2,76	damaging	0,55	damaging	0,06	deleterious	4,01	23,6	0,1	0,4	disease	0,54	disease	0,8	disease	0,71	disease	0,56	1	neutral	0,95	neutral	0,25	deleterious	1	deleterious	0,77	low_impact	-1,96	medium_impact	0,15	medium_impact	1,42	0,13	0,8	2,61	6,92	N	0,45	N	0,95	disease_causing	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10289	10289	A	C	MI.15458	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	231	77	W	C	tgA/tgC	9,15	1	0	probably_damaging	0,99	neutral	0,18	neutral	1	deleterious	-4,27	deleterious	-12,15	high_impact	4,15	damaging	0,6	damaging	0,03	deleterious	4,02	23,6	0,08	0,35	disease	0,74	disease	0,81	disease	0,76	disease	0,73	5	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,78	low_impact	-2,52	medium_impact	-0,18	high_impact	2,7	0,15	0,8	2,61	6,92	P	0,6	P	0,98	polymorphism	1	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10289	10289	A	T	MI.15459	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	231	77	W	C	tgA/tgT	9,15	1	0	probably_damaging	0,99	neutral	0,18	neutral	1	deleterious	-4,27	deleterious	-12,15	high_impact	4,15	damaging	0,6	damaging	0,03	deleterious	4,1	23,7	0,08	0,35	disease	0,74	disease	0,81	disease	0,76	disease	0,73	5	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,78	low_impact	-2,52	medium_impact	-0,18	high_impact	2,7	0,15	0,8	2,61	6,92	P	0,61	P	0,98	polymorphism	1	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8413	8413	A	C	MI.1546	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	48	16	M	I	atA/atC	1,75	0	0	possibly_damaging	0,82	neutral	0,4	neutral	1,91	neutral	4,18	deleterious	-3,33	medium_impact	2,29	neutral	0,95	neutral	0,52	deleterious	3,01	22,3	0,55484047	0,85	neutral	0,45	neutral	0,31	disease	0,73	neutral	0,17	7	neutral	0,82	neutral	0,29	NA	0	deleterious	0,57	low_impact	-1,38	medium_impact	0,19	medium_impact	0,87	0,63	0,85	NA	NA	N	0,49	N	0,64	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10290	10290	G	T	MI.15460	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	232	78	A	S	Gcc/Tcc	0,13	0,98	0	possibly_damaging	0,86	neutral	0,43	neutral	1	neutral	-2,26	neutral	-2,35	low_impact	1,9	neutral	0,7	neutral	0,56	deleterious	3,43	23	0,28	0,45	neutral	0,32	neutral	0,44	neutral	0,21	neutral	0,46	1	neutral	0,85	neutral	0,29	neutral	-3	deleterious	0,67	low_impact	-1,43	medium_impact	0,12	medium_impact	0,63	0,43	0,8	6,96	7,87	N	0,55	P	0,98	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10290	10290	G	A	MI.15461	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	232	78	A	T	Gcc/Acc	0,13	0,98	0	probably_damaging	0,95	neutral	0,4	neutral	0,97	neutral	-2,85	deleterious	-3,35	medium_impact	2,41	neutral	0,73	neutral	0,54	deleterious	4,09	23,7	0,19	0,45	neutral	0,35	disease	0,51	neutral	0,25	neutral	0,34	3	neutral	0,95	neutral	0,23	deleterious	1	deleterious	0,69	low_impact	-1,87	medium_impact	0,09	medium_impact	1,1	0,71	0,85	6,96	7,87	N	0,51	P	0,93	polymorphism	1	0,52	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	10290	10290	G	C	MI.15462	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	232	78	A	P	Gcc/Ccc	0,13	0,98	0	probably_damaging	0,98	neutral	0,23	neutral	0,89	deleterious	-4,67	deleterious	-4,38	medium_impact	2,75	damaging	0,59	damaging	0,22	deleterious	3,82	23,4	0,06	0,35	disease	0,59	disease	0,84	disease	0,67	disease	0,71	4	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,8	low_impact	-2,24	medium_impact	-0,1	medium_impact	1,41	0,33	0,8	6,96	7,87	N	0,47	N	0,96	polymorphism	1	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10291	10291	C	T	MI.15463	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	233	78	A	V	gCc/gTc	3,6	1	0	probably_damaging	0,95	neutral	0,53	neutral	1,02	neutral	-2,26	deleterious	-3,53	medium_impact	2,65	neutral	0,8	neutral	0,46	deleterious	4,33	24	0,17	0,45	neutral	0,3	disease	0,59	disease	0,54	neutral	0,5	0	neutral	0,95	neutral	0,29	deleterious	1	deleterious	0,68	low_impact	-1,87	medium_impact	0,22	medium_impact	1,32	0,66	0,8	6,96	7,87	N	0,45	N	0,79	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10291	10291	C	A	MI.15464	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	233	78	A	D	gCc/gAc	3,6	1	0	probably_damaging	0,96	neutral	0,21	neutral	0,95	deleterious	-4,05	deleterious	-5,11	high_impact	3,59	neutral	0,65	neutral	0,3	deleterious	4,58	24,4	0,04	0,35	disease	0,56	disease	0,81	disease	0,68	disease	0,68	4	neutral	0,97	neutral	0,13	deleterious	2	deleterious	0,77	low_impact	-1,96	medium_impact	-0,13	high_impact	2,18	0,23	0,8	6,96	7,87	P	0,57	P	0,96	polymorphism	1	0,69	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10291	10291	C	G	MI.15465	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	233	78	A	G	gCc/gGc	3,6	1	0	benign	0,06	neutral	0,33	neutral	0,91	deleterious	-3,84	deleterious	-2,7	medium_impact	2,79	neutral	0,74	neutral	0,58	deleterious	0,34	6,08	0,26	0,45	neutral	0,28	neutral	0,17	neutral	0,23	neutral	0,28	4	neutral	0,64	deleterious	0,64	neutral	-3	neutral	0,16	medium_impact	0,36	medium_impact	0,02	medium_impact	1,45	0,51	0,8	6,96	7,87	P	0,67	P	0,85	polymorphism	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10293	10293	C	G	MI.15466	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	235	79	L	V	Cta/Gta	-10,98	0	0	possibly_damaging	0,61	neutral	0,5	neutral	0,96	neutral	1,22	neutral	-0,08	neutral_impact	0,8	neutral	0,78	neutral	0,97	neutral	1,52	13,4	0,3	0,45	neutral	0,15	neutral	0,16	neutral	0,17	neutral	0,3	4	neutral	0,59	neutral	0,45	neutral	-3	deleterious	0,49	medium_impact	-0,89	medium_impact	0,19	medium_impact	-0,38	0,31	0,8	26,96	12,02	N	0,47	N	0,22	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10293	10293	C	A	MI.15467	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	235	79	L	M	Cta/Ata	-10,98	0	0	probably_damaging	0,97	neutral	0,29	neutral	0,87	neutral	-1,56	neutral	0,14	neutral_impact	0,66	neutral	0,78	neutral	0,98	deleterious	2,18	17,37	0,24	0,45	neutral	0,18	neutral	0,11	neutral	0,15	neutral	0,29	4	neutral	0,97	neutral	0,16	neutral	-2	deleterious	0,61	low_impact	-2,08	medium_impact	-0,03	medium_impact	-0,5	0,4	0,8	26,96	12,02	P	0,56	P	0,43	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10294	10294	T	C	MI.15468	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	236	79	L	P	cTa/cCa	-0,57	0	0	probably_damaging	0,98	neutral	0,25	neutral	0,81	deleterious	-3,2	neutral	-2,09	medium_impact	3,1	neutral	0,67	neutral	0,4	deleterious	2,59	20,1	0,03	0,35	neutral	0,4	disease	0,73	disease	0,56	disease	0,68	4	deleterious	0,98	neutral	0,14	deleterious	1	deleterious	0,74	low_impact	-2,24	medium_impact	-0,08	medium_impact	1,73	0,19	0,8	26,96	12,02	N	0,39	N	0,81	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10294	10294	T	G	MI.15469	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	236	79	L	R	cTa/cGa	-0,57	0	0	probably_damaging	0,97	neutral	0,34	neutral	0,82	neutral	-2,62	neutral	-2,17	medium_impact	3,44	neutral	0,72	neutral	0,51	deleterious	2,65	20,5	0,02	0,35	neutral	0,27	disease	0,69	disease	0,53	disease	0,6	2	neutral	0,97	neutral	0,19	deleterious	1	deleterious	0,71	low_impact	-2,08	medium_impact	0,03	high_impact	2,05	0,12	0,8	26,96	12,02	N	0,41	N	0,65	polymorphism	1	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8414	8414	C	T	MI.1547	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	49	17	L	F	Ctc/Ttc	-2,42	0	0,46	probably_damaging	0,99	neutral	0,31	neutral	1,71	neutral	-2,75	neutral	-1,98	low_impact	1,05	neutral	1	neutral	0,79	deleterious	2,42	18,98	0,51005936	0,85	neutral	0,27	neutral	0,15	neutral	0,37	neutral	0,06	9	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,71	low_impact	-2,65	medium_impact	0,1	medium_impact	-0,2	0,65	0,85	NA	NA	P	0,58	P	0,12	polymorphism	1	0,03	rs28358884	.	.	.	.	.	.	.	23,41	C8414T	Longevity	+	-	Reported	1
chrM	10294	10294	T	A	MI.15470	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	236	79	L	Q	cTa/cAa	-0,57	0	0	probably_damaging	0,98	neutral	0,31	neutral	0,82	neutral	-2,7	neutral	-1,61	medium_impact	2,63	neutral	0,77	neutral	0,58	deleterious	2,59	20,1	0,05	0,35	neutral	0,26	neutral	0,45	neutral	0,38	neutral	0,47	1	deleterious	0,98	neutral	0,17	deleterious	1	deleterious	0,65	low_impact	-2,24	medium_impact	0	medium_impact	1,3	0,1	0,8	26,96	12,02	N	0,4	N	0,63	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10296	10296	C	A	MI.15471	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	238	80	Q	K	Caa/Aaa	-5,66	0	0	possibly_damaging	0,85	neutral	0,29	neutral	2,01	neutral	0,24	deleterious	-3,53	low_impact	1,86	neutral	0,74	damaging	0,08	deleterious	3,98	23,6	0,25	0,45	neutral	0,16	disease	0,61	neutral	0,36	neutral	0,35	3	neutral	0,88	neutral	0,22	neutral	-3	deleterious	0,64	low_impact	-1,4	medium_impact	-0,03	medium_impact	0,6	0,31	0,8	5,22	11,64	N	0,26	N	0,96	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10296	10296	C	G	MI.15472	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	238	80	Q	E	Caa/Gaa	-5,66	0	0	possibly_damaging	0,89	neutral	0,27	neutral	1,98	neutral	0,12	deleterious	-2,62	medium_impact	2,38	neutral	0,73	damaging	0,11	deleterious	3,14	22,6	0,36	0,5	neutral	0,25	disease	0,55	neutral	0,38	neutral	0,44	1	neutral	0,91	neutral	0,19	NA	0	deleterious	0,65	low_impact	-1,54	medium_impact	-0,05	medium_impact	1,07	0,58	0,8	5,22	11,64	N	0,3	N	0,93	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10297	10297	A	C	MI.15473	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	239	80	Q	P	cAa/cCa	1,98	0,95	0	benign	0,12	neutral	0,22	neutral	1,88	neutral	-1,96	deleterious	-4,86	medium_impact	2,85	neutral	0,65	damaging	0,09	deleterious	3,13	22,6	0,08	0,35	disease	0,55	disease	0,78	disease	0,7	disease	0,68	4	neutral	0,75	deleterious	0,55	neutral	-3	neutral	0,3	medium_impact	0,06	medium_impact	-0,12	medium_impact	1,5	0,31	0,8	5,22	11,64	N	0,38	N	0,96	polymorphism	1	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10297	10297	A	T	MI.15474	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	239	80	Q	L	cAa/cTa	1,98	0,95	0	probably_damaging	0,93	neutral	0,67	neutral	1,92	neutral	-1,27	deleterious	-6,31	medium_impact	2,19	neutral	0,83	damaging	0,21	deleterious	3,6	23,2	0,13	0,4	neutral	0,39	disease	0,72	neutral	0,43	neutral	0,47	1	neutral	0,91	neutral	0,37	deleterious	1	deleterious	0,71	low_impact	-1,73	medium_impact	0,36	medium_impact	0,9	0,17	0,8	5,22	11,64	N	0,3	N	0,97	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10297	10297	A	G	MI.15475	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	239	80	Q	R	cAa/cGa	1,98	0,95	0	probably_damaging	0,95	neutral	0,34	neutral	1,93	neutral	-0,48	deleterious	-3,54	medium_impact	3,48	neutral	0,67	damaging	0,09	deleterious	3,24	22,8	0,28	0,45	neutral	0,25	disease	0,73	disease	0,6	disease	0,64	3	neutral	0,95	neutral	0,2	deleterious	1	deleterious	0,73	low_impact	-1,87	medium_impact	0,03	high_impact	2,08	0,18	0,8	5,22	11,64	N	0,42	N	0,85	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10298	10298	A	C	MI.15476	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	240	80	Q	H	caA/caC	6,84	0,99	0	probably_damaging	0,99	neutral	0,54	neutral	1,89	neutral	-1,52	deleterious	-4,18	low_impact	1,68	neutral	0,83	neutral	0,81	deleterious	3,34	22,9	0,24	0,45	neutral	0,48	disease	0,58	neutral	0,34	neutral	0,38	2	deleterious	0,98	neutral	0,28	neutral	-2	deleterious	0,73	low_impact	-2,52	medium_impact	0,23	medium_impact	0,43	0,39	0,8	5,22	11,64	N	0,51	P	0,93	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10298	10298	A	T	MI.15477	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	240	80	Q	H	caA/caT	6,84	0,99	0	probably_damaging	0,99	neutral	0,54	neutral	1,89	neutral	-1,52	deleterious	-4,18	low_impact	1,68	neutral	0,83	neutral	0,81	deleterious	3,49	23,1	0,24	0,45	neutral	0,48	disease	0,58	neutral	0,34	neutral	0,38	2	deleterious	0,98	neutral	0,28	neutral	-2	deleterious	0,73	low_impact	-2,52	medium_impact	0,23	medium_impact	0,43	0,39	0,8	5,22	11,64	N	0,51	P	0,93	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10299	10299	A	C	MI.15478	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	241	81	T	P	Aca/Cca	1,52	0,72	0	probably_damaging	0,99	neutral	0,21	neutral	0,93	neutral	-1,9	deleterious	-2,89	medium_impact	2,19	neutral	0,63	damaging	0,09	deleterious	3,44	23	0,09	0,35	disease	0,53	disease	0,68	disease	0,62	disease	0,69	4	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,72	low_impact	-2,52	medium_impact	-0,13	medium_impact	0,9	0,25	0,8	8,7	9,15	N	0,31	N	0,99	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10299	10299	A	G	MI.15479	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	241	81	T	A	Aca/Gca	1,52	0,72	0	possibly_damaging	0,9	neutral	0,52	neutral	1,03	neutral	0,37	neutral	-1,54	low_impact	1,43	neutral	0,78	neutral	0,82	deleterious	2,26	17,88	0,36	0,5	neutral	0,24	neutral	0,22	neutral	0,44	neutral	0,42	2	neutral	0,89	neutral	0,31	neutral	-3	deleterious	0,6	low_impact	-1,58	medium_impact	0,21	medium_impact	0,2	0,24	0,8	8,7	9,15	N	0,35	N	0,86	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8414	8414	C	G	MI.1548	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	49	17	L	V	Ctc/Gtc	-2,42	0	0,46	probably_damaging	0,97	neutral	0,15	neutral	1,75	neutral	-1,92	neutral	-0,69	low_impact	1	neutral	1	neutral	0,93	deleterious	2,05	16,51	0,67403744	0,85	neutral	0,33	neutral	0,22	neutral	0,32	neutral	0,19	6	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,71	low_impact	-2,19	medium_impact	-0,13	medium_impact	-0,24	0,62	0,85	NA	NA	P	0,59	P	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10299	10299	A	T	MI.15480	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	241	81	T	S	Aca/Tca	1,52	0,72	0	possibly_damaging	0,82	neutral	0,42	neutral	1,02	neutral	0,28	neutral	-0,83	neutral_impact	0,78	neutral	0,76	neutral	0,96	neutral	1,62	13,95	0,44	0,55	neutral	0,3	neutral	0,19	neutral	0,27	neutral	0,36	3	neutral	0,82	neutral	0,3	neutral	-3	deleterious	0,58	low_impact	-1,31	medium_impact	0,11	medium_impact	-0,39	0,38	0,8	8,7	9,15	N	0,36	N	0,47	polymorphism	1	0,17	rs878918474	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10300	10300	C	A	MI.15481	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	242	81	T	K	aCa/aAa	-1,03	0	0	probably_damaging	0,95	neutral	0,31	neutral	1,05	neutral	0,58	neutral	-2,4	low_impact	1,92	neutral	0,69	damaging	0,12	deleterious	4,48	24,2	0,16	0,45	neutral	0,33	disease	0,54	neutral	0,5	neutral	0,5	0	neutral	0,96	neutral	0,18	neutral	-2	deleterious	0,66	low_impact	-1,87	medium_impact	0	medium_impact	0,65	0,42	0,8	8,7	9,15	N	0,29	N	0,97	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10300	10300	C	T	MI.15482	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	242	81	T	M	aCa/aTa	-1,03	0	0	probably_damaging	0,99	neutral	0,23	neutral	0,94	neutral	-1,68	neutral	-1,22	neutral_impact	0,7	neutral	0,78	neutral	0,93	deleterious	2,75	21,1	0,23	0,45	neutral	0,36	neutral	0,26	neutral	0,34	neutral	0,45	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,64	low_impact	-2,52	medium_impact	-0,1	medium_impact	-0,47	0,4	0,8	8,7	9,15	N	0,38	N	0,8	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10302	10302	A	T	MI.15483	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	244	82	T	S	Act/Tct	-11,47	0	0	benign	0,17	neutral	0,48	neutral	1,05	neutral	0,5	neutral	0,02	neutral_impact	-0,41	neutral	0,74	neutral	0,98	neutral	-0,78	0,05	0,4	0,5	neutral	0,1	neutral	0,09	neutral	0,2	neutral	0,26	5	neutral	0,43	deleterious	0,66	neutral	-6	neutral	0,11	medium_impact	-0,1	medium_impact	0,17	low_impact	-1,48	0,5	0,8	20,87	10,61	N	0,45	N	0,09	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10302	10302	A	G	MI.15484	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	244	82	T	A	Act/Gct	-11,47	0	0	benign	0	neutral	0,51	neutral	1,02	neutral	0,32	neutral	-1,43	low_impact	0,88	neutral	0,86	neutral	0,96	neutral	-0,52	0,2	0,33	0,5	neutral	0,13	neutral	0,16	neutral	0,35	neutral	0,26	5	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,07	medium_impact	1,99	medium_impact	0,2	medium_impact	-0,3	0,19	0,8	20,87	10,61	N	0,39	N	0	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10302	10302	A	C	MI.15485	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	244	82	T	P	Act/Cct	-11,47	0	0	possibly_damaging	0,53	neutral	0,23	neutral	0,94	neutral	-1,35	neutral	-1,36	neutral_impact	0,08	neutral	0,77	neutral	0,98	neutral	-0,27	0,76	0,1	0,4	neutral	0,27	neutral	0,38	neutral	0,37	neutral	0,44	1	neutral	0,76	neutral	0,35	neutral	-3	neutral	0,38	medium_impact	-0,76	medium_impact	-0,1	low_impact	-1,04	0,29	0,8	20,87	10,61	N	0,43	N	0,1	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10303	10303	C	A	MI.15486	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	245	82	T	N	aCt/aAt	-2,94	0	0	benign	0,03	neutral	0,36	neutral	1,01	neutral	-0,02	neutral	0,62	neutral_impact	-0,58	neutral	0,78	neutral	0,99	neutral	-0,34	0,53	0,34	0,5	neutral	0,12	neutral	0,22	neutral	0,22	neutral	0,39	2	neutral	0,62	deleterious	0,67	neutral	-6	neutral	0,08	medium_impact	0,65	medium_impact	0,05	low_impact	-1,64	0,42	0,8	20,87	10,61	N	0,35	N	0,14	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10303	10303	C	T	MI.15487	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	245	82	T	I	aCt/aTt	-2,94	0	0	benign	0,37	neutral	0,41	neutral	0,95	neutral	-1,53	neutral	-2,33	neutral_impact	0,78	neutral	0,8	neutral	0,9	deleterious	0,39	6,49	0,17	0,45	neutral	0,27	neutral	0,32	neutral	0,37	neutral	0,44	1	neutral	0,52	deleterious	0,52	neutral	-6	neutral	0,33	medium_impact	-0,51	medium_impact	0,1	medium_impact	-0,39	0,48	0,8	20,87	10,61	N	0,31	N	0,24	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10303	10303	C	G	MI.15488	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	245	82	T	S	aCt/aGt	-2,94	0	0	benign	0,17	neutral	0,48	neutral	1,05	neutral	0,5	neutral	0,02	neutral_impact	-0,41	neutral	0,74	neutral	0,98	neutral	-0,64	0,1	0,4	0,5	neutral	0,1	neutral	0,09	neutral	0,2	neutral	0,26	5	neutral	0,43	deleterious	0,66	neutral	-6	neutral	0,11	medium_impact	-0,1	medium_impact	0,17	low_impact	-1,48	0,5	0,8	20,87	10,61	N	0,44	N	0,09	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10305	10305	A	G	MI.15489	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	247	83	N	D	Aac/Gac	-11,47	0	0	possibly_damaging	0,86	neutral	0,21	neutral	0,94	neutral	-0,28	deleterious	-2,61	medium_impact	1,96	neutral	0,77	neutral	0,87	deleterious	2,17	17,31	0,66	0,7	neutral	0,25	neutral	0,33	neutral	0,44	neutral	0,44	1	neutral	0,91	neutral	0,18	NA	0	deleterious	0,55	low_impact	-1,43	medium_impact	-0,13	medium_impact	0,69	0,21	0,8	4,35	9,01	N	0,46	N	0,8	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8414	8414	C	A	MI.1549	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	49	17	L	I	Ctc/Atc	-2,42	0	0,46	probably_damaging	0,97	neutral	0,35	neutral	1,82	neutral	-1,14	neutral	0,13	neutral_impact	-0,56	neutral	0,99	neutral	0,93	deleterious	2,33	18,39	0,67403744	0,85	neutral	0,16	neutral	0,17	neutral	0,22	neutral	0,09	8	neutral	0,97	neutral	0,19	neutral	-2	deleterious	0,68	low_impact	-2,19	medium_impact	0,14	low_impact	-1,58	0,57	0,85	NA	NA	N	0,51	P	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10305	10305	A	C	MI.15490	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	247	83	N	H	Aac/Cac	-11,47	0	0	probably_damaging	0,98	neutral	0,54	neutral	0,92	neutral	-1,67	deleterious	-3,35	medium_impact	2,31	neutral	0,77	neutral	0,56	deleterious	1,95	15,92	0,44	0,55	neutral	0,31	neutral	0,37	neutral	0,45	neutral	0,45	1	deleterious	0,98	neutral	0,28	deleterious	1	deleterious	0,64	low_impact	-2,24	medium_impact	0,23	medium_impact	1,01	0,05	0,8	4,35	9,01	N	0,3	N	0,55	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10305	10305	A	T	MI.15491	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	247	83	N	Y	Aac/Tac	-11,47	0	0	probably_damaging	0,98	neutral	1	neutral	0,92	neutral	-2,39	deleterious	-5,42	medium_impact	2,4	neutral	0,86	neutral	0,66	deleterious	3,65	23,2	0,14	0,4	disease	0,52	neutral	0,44	neutral	0,47	neutral	0,38	2	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,68	low_impact	-2,24	high_impact	1,85	medium_impact	1,09	0,11	0,8	4,35	9,01	N	0,24	N	0,94	polymorphism	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10306	10306	A	C	MI.15492	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	248	83	N	T	aAc/aCc	-0,17	0	0	possibly_damaging	0,81	neutral	0,4	neutral	0,98	neutral	-0,69	deleterious	-3,14	low_impact	1,69	neutral	0,76	neutral	0,94	deleterious	0,46	7,13	0,39	0,5	neutral	0,23	neutral	0,21	neutral	0,36	neutral	0,37	3	neutral	0,82	neutral	0,3	neutral	-3	deleterious	0,5	low_impact	-1,29	medium_impact	0,09	medium_impact	0,44	0,13	0,8	4,35	9,01	N	0,42	N	0,7	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10306	10306	A	T	MI.15493	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	248	83	N	I	aAc/aTc	-0,17	0	0	probably_damaging	0,98	neutral	0,4	neutral	0,97	neutral	-2,32	deleterious	-5,96	medium_impact	2,63	neutral	0,8	damaging	0,13	deleterious	3,88	23,5	0,14	0,4	neutral	0,45	disease	0,6	disease	0,52	disease	0,57	1	neutral	0,98	neutral	0,21	deleterious	1	deleterious	0,68	low_impact	-2,24	medium_impact	0,09	medium_impact	1,3	0,1	0,8	4,35	9,01	N	0,24	N	0,96	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10306	10306	A	G	MI.15494	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	248	83	N	S	aAc/aGc	-0,17	0	0	benign	0,18	neutral	0,42	neutral	1,01	neutral	0,05	neutral	-2,29	low_impact	1,2	neutral	0,75	neutral	0,95	neutral	-0,27	0,78	0,58	0,65	neutral	0,19	neutral	0,1	neutral	0,35	neutral	0,29	4	neutral	0,5	deleterious	0,62	neutral	-6	neutral	0,13	medium_impact	-0,12	medium_impact	0,11	medium_impact	-0,01	0,13	0,8	4,35	9,01	N	0,46	N	0,72	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10307	10307	C	A	MI.15495	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	249	83	N	K	aaC/aaA	-0,17	0	0	possibly_damaging	0,86	neutral	0,3	neutral	0,98	neutral	0,3	deleterious	-3,33	medium_impact	1,98	neutral	0,82	neutral	0,67	deleterious	3,01	22,3	0,52	0,6	neutral	0,16	neutral	0,44	neutral	0,46	neutral	0,45	1	neutral	0,88	neutral	0,22	NA	0	deleterious	0,57	low_impact	-1,43	medium_impact	-0,01	medium_impact	0,71	0,29	0,8	4,35	9,01	N	0,35	N	0,33	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10307	10307	C	G	MI.15496	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	249	83	N	K	aaC/aaG	-0,17	0	0	possibly_damaging	0,86	neutral	0,3	neutral	0,98	neutral	0,3	deleterious	-3,33	medium_impact	1,98	neutral	0,82	neutral	0,67	deleterious	2,54	19,73	0,52	0,6	neutral	0,16	neutral	0,44	neutral	0,46	neutral	0,45	1	neutral	0,88	neutral	0,22	NA	0	deleterious	0,57	low_impact	-1,43	medium_impact	-0,01	medium_impact	0,71	0,29	0,8	4,35	9,01	N	0,35	N	0,33	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10308	10308	C	A	MI.15497	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	250	84	L	M	Ctg/Atg	-9,85	0	0	probably_damaging	0,97	neutral	0,26	neutral	0,91	neutral	-2,53	neutral	-0,68	low_impact	1,4	neutral	0,83	neutral	0,76	deleterious	2,61	20,3	0,27	0,45	neutral	0,35	neutral	0,29	neutral	0,41	neutral	0,45	1	neutral	0,98	neutral	0,15	neutral	-2	deleterious	0,65	low_impact	-2,08	medium_impact	-0,06	medium_impact	0,18	0,54	0,8	6,96	8,79	N	0,42	N	0,47	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10308	10308	C	G	MI.15498	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	250	84	L	V	Ctg/Gtg	-9,85	0	0	possibly_damaging	0,61	neutral	0,51	neutral	0,95	neutral	-1,44	neutral	-1,02	medium_impact	2,3	neutral	0,84	neutral	0,67	deleterious	0,45	7	0,28	0,45	neutral	0,19	neutral	0,32	neutral	0,35	neutral	0,43	1	neutral	0,59	neutral	0,45	NA	0	deleterious	0,47	medium_impact	-0,89	medium_impact	0,2	medium_impact	1	0,34	0,8	6,96	8,79	N	0,35	N	0,34	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10309	10309	T	G	MI.15499	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	251	84	L	R	cTg/cGg	-0,17	0	0	probably_damaging	0,98	neutral	0,34	neutral	0,9	deleterious	-3,74	deleterious	-3,29	medium_impact	3,36	neutral	0,67	damaging	0,09	deleterious	4,08	23,7	0,04	0,35	neutral	0,43	disease	0,82	disease	0,71	disease	0,79	6	neutral	0,98	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-2,24	medium_impact	0,03	medium_impact	1,97	0,15	0,8	6,96	8,79	N	0,29	N	0,86	polymorphism	1	0,66	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8598	8598	T	A	MI.155	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	72	24	I	M	atT/atA	3,83	0,43	0	probably_damaging	1	neutral	0,35	neutral	3,96	neutral	-2,76	neutral	-1,44	neutral_impact	-0,32	neutral	0,87	neutral	0,96	deleterious	2,04	16,44	0,5	0,65	disease	0,56	neutral	0,13	neutral	0,27	neutral	0,29	4	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,14	low_impact	-1,37	0,7	0,9	18,14	17,22	N	0,46	N	0,63	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8415	8415	T	C	MI.1550	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	50	17	L	P	cTc/cCc	-0,1	0	0	probably_damaging	1	deleterious	0,03	neutral	1,66	deleterious	-5,12	deleterious	-5,4	medium_impact	2,44	neutral	0,99	neutral	0,38	deleterious	3,79	23,4	0,22335685	0,85	disease	0,81	disease	0,62	disease	0,68	disease	0,62	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,82	low_impact	-3,6	medium_impact	-0,56	medium_impact	0,99	0,63	0,85	NA	NA	N	0,5	N	0,75	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10309	10309	T	C	MI.15500	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	251	84	L	P	cTg/cCg	-0,17	0	0	benign	0,17	neutral	0,24	neutral	0,89	deleterious	-3,85	neutral	-2,29	neutral_impact	0,78	neutral	0,74	neutral	0,87	deleterious	0,68	8,67	0,04	0,35	neutral	0,16	neutral	0,09	neutral	0,5	neutral	0,22	6	neutral	0,72	deleterious	0,54	neutral	-6	neutral	0,17	medium_impact	-0,1	medium_impact	-0,09	medium_impact	-0,39	0,26	0,8	6,96	8,79	N	0,47	N	0,54	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10309	10309	T	A	MI.15501	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	251	84	L	Q	cTg/cAg	-0,17	0	0	probably_damaging	0,98	neutral	0,29	neutral	0,9	deleterious	-3,9	deleterious	-3,06	medium_impact	2,87	neutral	0,74	damaging	0,16	deleterious	3,08	22,5	0,06	0,35	neutral	0,44	disease	0,61	neutral	0,48	neutral	0,49	0	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,72	low_impact	-2,24	medium_impact	-0,03	medium_impact	1,52	0,23	0,8	6,96	8,79	N	0,34	N	0,81	polymorphism	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10311	10311	C	A	MI.15502	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	253	85	P	T	Cca/Aca	-11,01	0	0	benign	0,19	neutral	0,41	neutral	1,07	neutral	1,67	neutral	1,46	neutral_impact	-0,64	neutral	0,79	neutral	0,98	neutral	-0,96	0,02	0,23	0,45	neutral	0,09	neutral	0,06	neutral	0,28	neutral	0,23	5	neutral	0,51	deleterious	0,61	neutral	-6	neutral	0,12	medium_impact	-0,15	medium_impact	0,1	low_impact	-1,7	0,59	0,8	20	12,34	N	0,39	N	0,13	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10311	10311	C	T	MI.15503	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	253	85	P	S	Cca/Tca	-11,01	0	0	benign	0,01	neutral	0,41	neutral	1,05	neutral	1,66	neutral	1,38	neutral_impact	-0,44	neutral	0,86	neutral	0,99	neutral	-0,13	1,5	0,31	0,45	neutral	0,1	neutral	0,14	neutral	0,31	neutral	0,26	5	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,07	medium_impact	1,09	medium_impact	0,1	low_impact	-1,51	0,19	0,8	20	12,34	N	0,35	N	0,25	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10311	10311	C	G	MI.15504	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	253	85	P	A	Cca/Gca	-11,01	0	0	benign	0,08	neutral	0,5	neutral	1,09	neutral	1,98	neutral	0,2	low_impact	0,92	neutral	0,79	neutral	0,83	neutral	-0,77	0,05	0,23	0,45	neutral	0,12	neutral	0,11	neutral	0,41	neutral	0,3	4	neutral	0,43	deleterious	0,71	neutral	-6	neutral	0,1	medium_impact	0,24	medium_impact	0,19	medium_impact	-0,27	0,59	0,8	20	12,34	N	0,39	N	0,45	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10312	10312	C	A	MI.15505	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	254	85	P	Q	cCa/cAa	-0,17	0	0	benign	0,04	neutral	0,3	neutral	1,01	neutral	0,53	neutral	0,64	low_impact	1,2	neutral	0,81	neutral	0,85	deleterious	0,66	8,53	0,16	0,45	neutral	0,15	neutral	0,22	neutral	0,39	neutral	0,4	2	neutral	0,68	deleterious	0,63	neutral	-6	neutral	0,08	medium_impact	0,53	medium_impact	-0,01	medium_impact	-0,01	0,39	0,8	20	12,34	N	0,39	N	0,49	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10312	10312	C	T	MI.15506	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	254	85	P	L	cCa/cTa	-0,17	0	0	benign	0,01	neutral	0,66	neutral	1,23	neutral	3,21	neutral	-0,14	neutral_impact	-0,27	neutral	0,83	neutral	0,89	deleterious	0	2,57	0,16	0,45	neutral	0,1	neutral	0,2	neutral	0,34	neutral	0,33	3	neutral	0,32	deleterious	0,83	neutral	-6	neutral	0,07	medium_impact	1,09	medium_impact	0,35	low_impact	-1,36	0,59	0,8	20	12,34	N	0,34	N	0,62	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10312	10312	C	G	MI.15507	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	254	85	P	R	cCa/cGa	-0,17	0	0	benign	0,29	neutral	0,35	neutral	1	neutral	0,12	neutral	0,39	low_impact	1,9	neutral	0,8	neutral	0,46	deleterious	0,21	4,82	0,13	0,4	neutral	0,16	neutral	0,41	disease	0,52	neutral	0,45	1	neutral	0,58	deleterious	0,53	neutral	-6	neutral	0,25	medium_impact	-0,37	medium_impact	0,04	medium_impact	0,63	0,41	0,8	20	12,34	N	0,34	N	0,67	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10314	10314	C	A	MI.15508	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	256	86	L	M	Cta/Ata	-9,85	0	0	benign	0,08	neutral	0,33	neutral	0,82	neutral	-1,79	neutral	-0,16	neutral_impact	0,58	neutral	0,85	neutral	0,97	deleterious	2,27	17,96	0,27	0,45	neutral	0,23	neutral	0,18	neutral	0,31	neutral	0,3	4	neutral	0,63	deleterious	0,63	neutral	-6	neutral	0,15	medium_impact	0,24	medium_impact	0,02	medium_impact	-0,58	0,52	0,8	6,09	10,69	N	0,47	N	0,03	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10314	10314	C	G	MI.15509	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	256	86	L	V	Cta/Gta	-9,85	0	0	benign	0,04	neutral	0,53	neutral	0,88	neutral	-0,71	neutral	-0,62	low_impact	0,86	neutral	0,88	neutral	0,94	neutral	1,55	13,56	0,28	0,45	neutral	0,12	neutral	0,29	neutral	0,41	neutral	0,42	2	neutral	0,42	deleterious	0,75	neutral	-6	neutral	0,1	medium_impact	0,53	medium_impact	0,22	medium_impact	-0,32	0,39	0,8	6,09	10,69	N	0,33	N	0,2	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8415	8415	T	A	MI.1551	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	50	17	L	H	cTc/cAc	-0,1	0	0	probably_damaging	1	neutral	0,09	neutral	1,66	deleterious	-5,08	deleterious	-5,23	medium_impact	2,44	neutral	0,99	neutral	0,53	deleterious	4,14	23,8	0,24042424	0,85	disease	0,84	disease	0,56	disease	0,64	disease	0,62	2	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,28	medium_impact	0,99	0,53	0,85	NA	NA	N	0,52	P	0,56	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10315	10315	T	A	MI.15510	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	257	86	L	Q	cTa/cAa	-2,94	0	0	possibly_damaging	0,87	neutral	0,31	neutral	0,81	neutral	-2,86	neutral	-1,63	medium_impact	2,07	neutral	0,8	neutral	0,81	deleterious	2,58	19,99	0,07	0,35	neutral	0,41	disease	0,53	neutral	0,46	neutral	0,48	0	neutral	0,89	neutral	0,22	NA	0	deleterious	0,65	low_impact	-1,46	medium_impact	0	medium_impact	0,79	0,17	0,8	6,09	10,69	N	0,34	N	0,57	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10315	10315	T	G	MI.15511	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	257	86	L	R	cTa/cGa	-2,94	0	0	possibly_damaging	0,74	neutral	0,24	neutral	0,8	neutral	-2,82	neutral	-2,05	medium_impact	2,92	neutral	0,71	neutral	0,44	deleterious	2,55	19,78	0,06	0,35	neutral	0,4	disease	0,78	disease	0,52	disease	0,67	3	neutral	0,83	neutral	0,25	NA	0	deleterious	0,7	low_impact	-1,13	medium_impact	-0,09	medium_impact	1,57	0,15	0,8	6,09	10,69	N	0,39	N	0,49	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10315	10315	T	C	MI.15512	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	257	86	L	P	cTa/cCa	-2,94	0	0	possibly_damaging	0,8	neutral	0,16	neutral	0,79	deleterious	-3,8	neutral	-2,41	low_impact	1,43	neutral	0,76	neutral	0,49	deleterious	2,58	19,97	0,05	0,35	disease	0,51	disease	0,79	disease	0,61	disease	0,7	4	neutral	0,9	neutral	0,18	neutral	-3	deleterious	0,74	low_impact	-1,26	medium_impact	-0,21	medium_impact	0,2	0,18	0,8	6,09	10,69	N	0,32	N	0,81	polymorphism	1	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10317	10317	A	C	MI.15513	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	259	87	M	L	Ata/Cta	-12,62	0	0	benign	0,04	neutral	0,77	neutral	1,08	neutral	1,57	neutral	-1,09	neutral_impact	0,5	neutral	0,81	neutral	0,91	neutral	1,39	12,72	0,29	0,45	neutral	0,15	disease	0,51	neutral	0,44	neutral	0,44	1	neutral	0,16	deleterious	0,87	neutral	-6	neutral	0,15	medium_impact	0,53	medium_impact	0,48	medium_impact	-0,65	0,36	0,8	9,57	8,6	N	0,29	N	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10317	10317	A	T	MI.15514	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	259	87	M	L	Ata/Tta	-12,62	0	0	benign	0,04	neutral	0,77	neutral	1,08	neutral	1,57	neutral	-1,09	neutral_impact	0,5	neutral	0,81	neutral	0,91	neutral	1,49	13,26	0,29	0,45	neutral	0,15	disease	0,51	neutral	0,44	neutral	0,44	1	neutral	0,16	deleterious	0,87	neutral	-6	neutral	0,15	medium_impact	0,53	medium_impact	0,48	medium_impact	-0,65	0,36	0,8	9,57	8,6	N	0,3	N	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10317	10317	A	G	MI.15515	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	259	87	M	V	Ata/Gta	-12,62	0	0	benign	0,04	neutral	0,39	neutral	1,09	neutral	1,34	neutral	-0,89	neutral_impact	0,44	neutral	0,82	neutral	0,9	neutral	-0,24	0,89	0,25	0,45	neutral	0,15	neutral	0,5	neutral	0,45	neutral	0,43	1	neutral	0,58	deleterious	0,68	neutral	-6	neutral	0,15	medium_impact	0,53	medium_impact	0,08	medium_impact	-0,71	0,44	0,8	9,57	8,6	N	0,32	N	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10318	10318	T	C	MI.15516	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	260	87	M	T	aTa/aCa	1,68	0	0	benign	0,01	neutral	0,57	neutral	1,04	neutral	0,26	neutral	0,08	neutral_impact	0,31	neutral	0,82	neutral	0,97	neutral	-1,63	0	0,15	0,45	neutral	0,16	neutral	0,12	neutral	0,4	neutral	0,25	5	neutral	0,42	deleterious	0,78	neutral	-6	neutral	0,1	medium_impact	1,09	medium_impact	0,26	medium_impact	-0,82	0,21	0,8	9,57	8,6	N	0,36	N	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10318	10318	T	A	MI.15517	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	260	87	M	K	aTa/aAa	1,68	0	0	benign	0,21	neutral	0,24	neutral	0,99	neutral	-0,93	deleterious	-2,51	medium_impact	2,31	neutral	0,72	neutral	0,4	deleterious	2,38	18,69	0,05	0,35	neutral	0,36	disease	0,75	disease	0,6	disease	0,69	4	neutral	0,71	deleterious	0,52	neutral	-3	neutral	0,29	medium_impact	-0,2	medium_impact	-0,09	medium_impact	1,01	0,2	0,8	9,57	8,6	N	0,39	N	1	disease_causing	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10319	10319	A	C	MI.15518	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	261	87	M	I	atA/atC	1,21	0	0	benign	0,01	neutral	0,62	neutral	1,05	neutral	1,15	neutral	-1,32	low_impact	1,34	neutral	0,83	neutral	0,77	neutral	1,41	12,85	0,26	0,45	neutral	0,19	disease	0,57	disease	0,53	disease	0,55	1	neutral	0,36	deleterious	0,81	neutral	-6	neutral	0,16	medium_impact	1,09	medium_impact	0,31	medium_impact	0,12	0,52	0,8	9,57	8,6	N	0,29	N	0,96	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10319	10319	A	T	MI.15519	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	261	87	M	I	atA/atT	1,21	0	0	benign	0,01	neutral	0,62	neutral	1,05	neutral	1,15	neutral	-1,32	low_impact	1,34	neutral	0,83	neutral	0,77	neutral	1,65	14,11	0,26	0,45	neutral	0,19	disease	0,57	disease	0,53	disease	0,55	1	neutral	0,36	deleterious	0,81	neutral	-6	neutral	0,16	medium_impact	1,09	medium_impact	0,31	medium_impact	0,12	0,52	0,8	9,57	8,6	N	0,29	N	0,96	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8415	8415	T	G	MI.1552	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	50	17	L	R	cTc/cGc	-0,1	0	0	probably_damaging	1	neutral	0,06	neutral	1,67	deleterious	-4,55	deleterious	-5	medium_impact	2,44	neutral	1	neutral	0,49	deleterious	4,02	23,6	0,22218516	0,85	disease	0,77	disease	0,67	disease	0,67	disease	0,61	2	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	-0,38	medium_impact	0,99	0,5	0,85	NA	NA	N	0,53	P	0,65	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10320	10320	G	T	MI.15520	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	262	88	V	F	Gtt/Ttt	-1,78	0	0	benign	0	neutral	0,74	neutral	1,09	neutral	0,68	neutral	-1,19	neutral_impact	-0,38	neutral	0,76	neutral	0,75	deleterious	0,09	3,53	0,07	0,35	neutral	0,27	neutral	0,26	neutral	0,37	neutral	0,42	2	neutral	0,25	deleterious	0,87	neutral	-6	neutral	0,1	medium_impact	1,99	medium_impact	0,44	low_impact	-1,46	0,4	0,8	16,52	14,07	N	0,27	N	0,33	polymorphism	1	0,19	rs28358276	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10320	10320	G	A	MI.15521	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	262	88	V	I	Gtt/Att	-1,78	0	0	benign	0	neutral	0,43	neutral	0,98	neutral	-0,14	neutral	0,5	neutral_impact	-0,78	neutral	0,82	neutral	0,97	deleterious	0,1	3,56	0,42	0,55	neutral	0,13	neutral	0,12	neutral	0,33	neutral	0,26	5	neutral	0,57	deleterious	0,72	neutral	-6	neutral	0,08	medium_impact	1,99	medium_impact	0,12	low_impact	-1,82	0,71	0,85	16,52	14,07	N	0,34	N	0,04	polymorphism	1	0,15	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	10320	10320	G	C	MI.15522	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	262	88	V	L	Gtt/Ctt	-1,78	0	0	benign	0	neutral	0,68	neutral	1,09	neutral	0,68	neutral	0,88	neutral_impact	-1,38	neutral	0,81	neutral	0,97	neutral	-1,13	0,01	0,26	0,45	neutral	0,09	neutral	0,13	neutral	0,29	neutral	0,22	6	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,06	medium_impact	1,99	medium_impact	0,37	low_impact	-2,37	0,54	0,8	16,52	14,07	N	0,3	N	0,07	polymorphism	1	0,15	rs28358276	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10321	10321	T	G	MI.15523	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	263	88	V	G	gTt/gGt	-1,09	0	0	benign	0,04	neutral	0,34	neutral	0,88	neutral	-2,07	deleterious	-4,47	neutral_impact	-0,38	neutral	0,72	neutral	0,49	deleterious	1,94	15,86	0,05	0,35	neutral	0,38	neutral	0,35	disease	0,65	neutral	0,49	0	neutral	0,64	deleterious	0,65	neutral	-6	neutral	0,14	medium_impact	0,53	medium_impact	0,03	low_impact	-1,46	0,24	0,8	16,52	14,07	N	0,32	N	0,61	polymorphism	1	0,49	rs193302928	Likely benign	not_provided	RCV000224675.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	10321	10321	T	C	MI.15524	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	263	88	V	A	gTt/gCt	-1,09	0	0	benign	0	neutral	0,52	neutral	0,93	neutral	-0,77	neutral	-2,05	neutral_impact	0,42	neutral	0,79	neutral	0,86	deleterious	0,56	7,89	0,15	0,4	neutral	0,17	neutral	0,17	neutral	0,43	neutral	0,3	4	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,09	medium_impact	1,99	medium_impact	0,21	medium_impact	-0,72	0,23	0,8	16,52	14,07	N	0,33	N	0,21	polymorphism	1	0,35	rs193302928	Likely benign	not_provided	RCV000224675.1	MedGen	bladder tumor	.	.	.	.	.	.	.	.	.
chrM	10321	10321	T	A	MI.15525	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	263	88	V	D	gTt/gAt	-1,09	0	0	benign	0,08	neutral	0,2	neutral	0,86	deleterious	-3,07	deleterious	-4,33	low_impact	1,83	neutral	0,7	neutral	0,46	deleterious	2,69	20,8	0,04	0,35	neutral	0,49	disease	0,58	disease	0,75	disease	0,76	5	neutral	0,78	deleterious	0,56	neutral	-6	neutral	0,23	medium_impact	0,24	medium_impact	-0,14	medium_impact	0,57	0,17	0,8	16,52	14,07	N	0,37	N	0,62	polymorphism	1	0,69	rs193302928	Likely benign	not_provided	RCV000224675.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	10323	10323	A	C	MI.15526	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	265	89	M	L	Atg/Ctg	-11,7	0	0	benign	0,04	neutral	0,95	neutral	1,15	neutral	1,63	neutral	0,14	neutral_impact	-0,88	neutral	0,74	neutral	0,97	neutral	-1,18	0,01	0,25	0,45	neutral	0,1	neutral	0,21	neutral	0,32	neutral	0,35	3	neutral	0,01	deleterious	0,96	neutral	-6	neutral	0,08	medium_impact	0,53	medium_impact	0,9	low_impact	-1,92	0,28	0,8	27,83	15,56	N	0,38	N	0,04	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10323	10323	A	T	MI.15527	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	265	89	M	L	Atg/Ttg	-11,7	0	0	benign	0,04	neutral	0,95	neutral	1,15	neutral	1,63	neutral	0,14	neutral_impact	-0,88	neutral	0,74	neutral	0,97	neutral	-1,18	0,01	0,25	0,45	neutral	0,1	neutral	0,21	neutral	0,32	neutral	0,35	3	neutral	0,01	deleterious	0,96	neutral	-6	neutral	0,08	medium_impact	0,53	medium_impact	0,9	low_impact	-1,92	0,28	0,8	27,83	15,56	N	0,38	N	0,04	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10323	10323	A	G	MI.15528	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	265	89	M	V	Atg/Gtg	-11,7	0	0	benign	0,04	neutral	0,45	neutral	1,15	neutral	1,59	neutral	-0,19	neutral_impact	0,31	neutral	0,82	neutral	0,95	neutral	-0,5	0,22	0,24	0,45	neutral	0,08	neutral	0,3	neutral	0,49	neutral	0,41	2	neutral	0,52	deleterious	0,71	neutral	-6	neutral	0,1	medium_impact	0,53	medium_impact	0,14	medium_impact	-0,82	0,38	0,8	27,83	15,56	N	0,33	N	0,02	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10324	10324	T	A	MI.15529	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	266	89	M	K	aTg/aAg	-1,09	0	0	benign	0	neutral	0,11	neutral	0,96	neutral	-0,99	neutral	-1,61	low_impact	0,98	neutral	0,89	neutral	0,71	deleterious	0,69	8,76	0,05	0,35	neutral	0,33	disease	0,56	disease	0,62	neutral	0,48	0	neutral	0,89	deleterious	0,56	neutral	-6	neutral	0,16	medium_impact	1,99	medium_impact	-0,31	medium_impact	-0,21	0,25	0,8	27,83	15,56	N	0,39	N	0,23	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8417	8417	C	T	MI.1553	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	52	18	L	F	Ctt/Ttt	-1,26	0	0	probably_damaging	0,99	neutral	0,45	neutral	1,75	neutral	-1,06	deleterious	-2,86	medium_impact	2	neutral	0,99	neutral	0,72	deleterious	2,52	19,59	0,6294906	0,85	neutral	0,48	neutral	0,13	neutral	0,39	neutral	0,1	8	deleterious	0,99	neutral	0,23	deleterious	1	deleterious	0,71	low_impact	-2,65	medium_impact	0,24	medium_impact	0,62	0,5	0,85	2,94	7,61	N	0,45	N	0,35	polymorphism	1	0,08	rs199616772	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10324	10324	T	C	MI.15530	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	266	89	M	T	aTg/aCg	-1,09	0	0	benign	0	neutral	0,53	neutral	1,02	neutral	0,4	neutral	0,21	neutral_impact	-0,5	neutral	0,88	neutral	0,98	neutral	-1,26	0,01	0,13	0,4	neutral	0,11	neutral	0,14	neutral	0,36	neutral	0,24	5	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,08	medium_impact	1,99	medium_impact	0,22	low_impact	-1,57	0,12	0,8	27,83	15,56	N	0,33	N	0,02	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10325	10325	G	C	MI.15531	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	267	89	M	I	atG/atC	-5,24	0	0,01	benign	0,09	neutral	0,49	neutral	1,16	neutral	1,67	neutral	-0,2	neutral_impact	-0,14	neutral	0,73	neutral	0,98	neutral	-0,25	0,86	0,27	0,45	neutral	0,09	neutral	0,21	neutral	0,34	neutral	0,33	3	neutral	0,44	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	0,19	medium_impact	0,18	low_impact	-1,24	0,34	0,8	27,83	15,56	N	0,4	N	0,04	disease_causing	1	0,15	rs386829097	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10325	10325	G	T	MI.15532	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	267	89	M	I	atG/atT	-5,24	0	0,01	benign	0,09	neutral	0,49	neutral	1,16	neutral	1,67	neutral	-0,2	neutral_impact	-0,14	neutral	0,73	neutral	0,98	neutral	-0,15	1,38	0,27	0,45	neutral	0,09	neutral	0,21	neutral	0,34	neutral	0,33	3	neutral	0,44	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	0,19	medium_impact	0,18	low_impact	-1,24	0,34	0,8	27,83	15,56	N	0,4	N	0,04	disease_causing	1	0,15	rs386829097	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10326	10326	T	G	MI.15533	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	268	90	S	A	Tca/Gca	-14,47	0	0	possibly_damaging	0,62	neutral	0,4	neutral	0,97	neutral	-0,33	neutral	-0,05	neutral_impact	0,68	neutral	0,79	neutral	0,9	deleterious	2,38	18,7	0,24	0,45	neutral	0,14	neutral	0,27	neutral	0,32	neutral	0,43	2	neutral	0,66	neutral	0,39	neutral	-3	deleterious	0,48	medium_impact	-0,91	medium_impact	0,09	medium_impact	-0,49	0,42	0,8	23,48	11,99	N	0,32	N	0,14	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10326	10326	T	C	MI.15534	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	268	90	S	P	Tca/Cca	-14,47	0	0	probably_damaging	0,95	neutral	0,11	neutral	0,91	neutral	-1,86	neutral	-1,56	medium_impact	2	damaging	0,59	neutral	0,38	deleterious	2,91	21,9	0,08	0,35	neutral	0,38	disease	0,83	disease	0,51	disease	0,73	5	deleterious	0,98	neutral	0,08	deleterious	1	deleterious	0,75	low_impact	-1,87	medium_impact	-0,31	medium_impact	0,73	0,34	0,8	23,48	11,99	N	0,31	N	0,63	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10326	10326	T	A	MI.15535	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	268	90	S	T	Tca/Aca	-14,47	0	0	benign	0,12	neutral	0,56	neutral	0,97	neutral	-0,34	neutral	0,92	neutral_impact	0,06	neutral	0,9	neutral	1	deleterious	1,95	15,91	0,23	0,45	neutral	0,11	neutral	0,14	neutral	0,19	neutral	0,27	5	neutral	0,34	deleterious	0,72	neutral	-6	neutral	0,18	medium_impact	0,06	medium_impact	0,25	low_impact	-1,05	0,43	0,8	23,48	11,99	N	0,39	N	0,14	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10327	10327	C	G	MI.15536	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	269	90	S	W	tCa/tGa	0,52	0	0	probably_damaging	0,98	neutral	0,37	neutral	0,89	neutral	-2,85	neutral	-0,22	neutral_impact	0,37	neutral	0,78	neutral	0,83	neutral	1,64	14,05	0,08	0,35	neutral	0,15	neutral	0,32	neutral	0,23	neutral	0,44	1	deleterious	0,98	neutral	0,2	neutral	-2	deleterious	0,64	low_impact	-2,24	medium_impact	0,06	medium_impact	-0,77	0,22	0,8	23,48	11,99	N	0,34	N	0,6	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10327	10327	C	T	MI.15537	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	269	90	S	L	tCa/tTa	0,52	0	0	benign	0,08	neutral	0,95	neutral	1	neutral	0,03	neutral	1,21	neutral_impact	-0,29	neutral	0,83	neutral	0,96	deleterious	2,78	21,3	0,1	0,4	neutral	0,12	disease	0,53	neutral	0,22	neutral	0,39	2	neutral	0,02	deleterious	0,94	neutral	-6	neutral	0,14	medium_impact	0,24	medium_impact	0,9	low_impact	-1,37	0,43	0,8	23,48	11,99	N	0,25	N	0,2	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10329	10329	T	C	MI.15538	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	271	91	S	P	Tcc/Ccc	-1,09	0	0	probably_damaging	0,97	neutral	0,24	neutral	0,94	neutral	-2,06	deleterious	-2,77	medium_impact	2,53	damaging	0,49	neutral	0,31	deleterious	4,03	23,7	0,07	0,35	disease	0,51	disease	0,87	disease	0,74	disease	0,8	6	neutral	0,98	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-2,08	medium_impact	-0,09	medium_impact	1,21	0,34	0,8	19,13	12,1	N	0,36	N	0,69	polymorphism	1	0,69	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10329	10329	T	A	MI.15539	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	271	91	S	T	Tcc/Acc	-1,09	0	0	benign	0,18	neutral	0,46	neutral	1,06	neutral	0,87	neutral	-0,85	neutral_impact	0,24	neutral	0,86	neutral	0,97	deleterious	2,54	19,75	0,25	0,45	neutral	0,23	neutral	0,14	neutral	0,36	neutral	0,28	4	neutral	0,45	deleterious	0,64	neutral	-6	neutral	0,28	medium_impact	-0,12	medium_impact	0,15	medium_impact	-0,89	0,35	0,8	19,13	12,1	N	0,37	N	0,06	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8417	8417	C	A	MI.1554	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	52	18	L	I	Ctt/Att	-1,26	0	0	probably_damaging	0,97	neutral	0,65	neutral	1,67	neutral	0,47	neutral	-0,71	low_impact	1,39	neutral	0,99	neutral	0,85	deleterious	2,42	18,96	0,56962521	0,85	neutral	0,26	neutral	0,1	neutral	0,24	neutral	0,05	9	neutral	0,97	neutral	0,34	neutral	-2	deleterious	0,67	low_impact	-2,19	medium_impact	0,44	medium_impact	0,09	0,67	0,85	2,94	7,61	N	0,42	N	0,1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10329	10329	T	G	MI.15540	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	271	91	S	A	Tcc/Gcc	-1,09	0	0	possibly_damaging	0,73	neutral	0,6	neutral	1,05	neutral	0,74	neutral	0,43	neutral_impact	-0,08	neutral	0,78	neutral	0,99	neutral	1,02	10,77	0,28	0,45	neutral	0,09	neutral	0,09	neutral	0,31	neutral	0,21	6	neutral	0,68	neutral	0,44	neutral	-3	deleterious	0,53	low_impact	-1,11	medium_impact	0,29	low_impact	-1,18	0,31	0,8	19,13	12,1	N	0,34	N	0,02	polymorphism	1	0,15	rs878943163	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10330	10330	C	G	MI.15541	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	272	91	S	C	tCc/tGc	-2,01	0	0	probably_damaging	0,99	neutral	0,17	neutral	0,95	neutral	-1,66	neutral	-2,16	medium_impact	2,31	neutral	0,62	neutral	0,33	deleterious	3,61	23,2	0,1	0,4	disease	0,61	disease	0,65	disease	0,6	disease	0,71	4	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,73	low_impact	-2,52	medium_impact	-0,19	medium_impact	1,01	0,25	0,8	19,13	12,1	N	0,32	N	0,53	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10330	10330	C	A	MI.15542	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	272	91	S	Y	tCc/tAc	-2,01	0	0	probably_damaging	0,98	neutral	1	neutral	0,99	neutral	-0,2	deleterious	-3,29	medium_impact	2,46	neutral	0,65	neutral	0,48	deleterious	4,22	23,9	0,08	0,35	disease	0,7	disease	0,68	disease	0,64	disease	0,71	4	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,78	low_impact	-2,24	high_impact	1,85	medium_impact	1,15	0,33	0,8	19,13	12,1	N	0,21	N	0,82	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10330	10330	C	T	MI.15543	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	272	91	S	F	tCc/tTc	-2,01	0	0	probably_damaging	0,98	neutral	0,81	neutral	1,01	neutral	0,24	deleterious	-3,25	low_impact	1,71	damaging	0,56	neutral	0,47	deleterious	4,24	23,9	0,08	0,35	disease	0,67	disease	0,75	neutral	0,5	disease	0,52	0	deleterious	0,98	neutral	0,42	neutral	-2	deleterious	0,8	low_impact	-2,24	medium_impact	0,54	medium_impact	0,46	0,32	0,8	19,13	12,1	N	0,25	N	0,86	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10332	10332	C	T	MI.15544	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	274	92	L	F	Ctc/Ttc	-8,7	0	0	possibly_damaging	0,77	neutral	0,84	neutral	0,91	neutral	-1,56	neutral	-0,75	neutral_impact	0,7	neutral	0,76	neutral	0,98	deleterious	1,91	15,66	0,27	0,45	neutral	0,22	neutral	0,19	neutral	0,27	neutral	0,36	3	neutral	0,73	deleterious	0,54	neutral	-3	deleterious	0,59	low_impact	-1,19	medium_impact	0,59	medium_impact	-0,47	0,48	0,8	18,26	12,33	N	0,31	N	0,14	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10332	10332	C	G	MI.15545	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	274	92	L	V	Ctc/Gtc	-8,7	0	0	benign	0,23	neutral	0,42	neutral	0,9	neutral	-0,84	neutral	-1,35	low_impact	1,38	neutral	0,8	neutral	0,77	deleterious	2,18	17,41	0,28	0,45	neutral	0,17	neutral	0,26	neutral	0,3	neutral	0,44	1	neutral	0,49	deleterious	0,6	neutral	-6	neutral	0,29	medium_impact	-0,24	medium_impact	0,11	medium_impact	0,16	0,57	0,8	18,26	12,33	N	0,33	N	0,34	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10332	10332	C	A	MI.15546	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	274	92	L	I	Ctc/Atc	-8,7	0	0	benign	0,07	neutral	0,72	neutral	0,97	neutral	-0,83	neutral	-0,74	low_impact	0,86	neutral	0,85	neutral	0,86	deleterious	2,69	20,7	0,28	0,45	neutral	0,15	neutral	0,26	neutral	0,26	neutral	0,43	2	neutral	0,19	deleterious	0,83	neutral	-6	neutral	0,14	medium_impact	0,3	medium_impact	0,42	medium_impact	-0,32	0,5	0,8	18,26	12,33	N	0,3	N	0,1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10333	10333	T	C	MI.15547	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	275	92	L	P	cTc/cCc	-2,94	0	0	probably_damaging	0,93	neutral	0,12	neutral	0,76	deleterious	-4	deleterious	-4,6	high_impact	3,73	damaging	0,57	neutral	0,3	deleterious	3,84	23,4	0,04	0,35	disease	0,51	disease	0,76	disease	0,61	disease	0,73	5	neutral	0,97	neutral	0,1	deleterious	2	deleterious	0,74	low_impact	-1,73	medium_impact	-0,29	high_impact	2,31	0,33	0,8	18,26	12,33	N	0,38	N	0,88	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10333	10333	T	A	MI.15548	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	275	92	L	H	cTc/cAc	-2,94	0	0	probably_damaging	0,97	neutral	0,31	neutral	0,77	deleterious	-3,95	deleterious	-3,91	high_impact	3,73	neutral	0,74	neutral	0,48	deleterious	2,96	22,1	0,06	0,35	neutral	0,49	disease	0,53	disease	0,52	disease	0,59	2	neutral	0,97	neutral	0,17	deleterious	2	deleterious	0,7	low_impact	-2,08	medium_impact	0	high_impact	2,31	0,17	0,8	18,26	12,33	N	0,45	N	0,7	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10333	10333	T	G	MI.15549	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	275	92	L	R	cTc/cGc	-2,94	0	0	possibly_damaging	0,88	neutral	0,2	neutral	0,78	deleterious	-3,38	deleterious	-3,87	high_impact	3,73	neutral	0,69	neutral	0,39	deleterious	3,12	22,6	0,04	0,35	neutral	0,4	disease	0,74	disease	0,59	disease	0,71	4	neutral	0,92	neutral	0,16	deleterious	1	deleterious	0,71	low_impact	-1,5	medium_impact	-0,14	high_impact	2,31	0,2	0,8	18,26	12,33	N	0,46	N	0,79	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8417	8417	C	G	MI.1555	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	52	18	L	V	Ctt/Gtt	-1,26	0	0	probably_damaging	0,97	neutral	0,2	neutral	1,59	neutral	-2,87	neutral	-1,18	low_impact	1,34	neutral	1	neutral	0,92	deleterious	1,98	16,08	0,6294906	0,85	neutral	0,31	neutral	0,13	neutral	0,36	neutral	0,1	8	deleterious	0,98	neutral	0,12	neutral	-2	deleterious	0,69	low_impact	-2,19	medium_impact	-0,05	medium_impact	0,05	0,46	0,85	2,94	7,61	P	0,61	P	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10335	10335	T	G	MI.15550	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	277	93	L	V	Tta/Gta	-20	0	0	benign	0,01	neutral	0,25	neutral	0,95	neutral	-0,07	neutral	0,08	low_impact	0,87	neutral	0,81	neutral	0,97	neutral	-0,83	0,04	0,22	0,45	neutral	0,14	neutral	0,18	neutral	0,24	neutral	0,28	4	neutral	0,74	deleterious	0,62	neutral	-6	neutral	0,1	medium_impact	1,09	medium_impact	-0,08	medium_impact	-0,31	0,39	0,8	15,65	9,34	N	0,44	N	0,16	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10335	10335	T	A	MI.15551	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	277	93	L	M	Tta/Ata	-20	0	0	benign	0,03	neutral	0,32	neutral	0,81	neutral	-1,96	neutral	-0,07	neutral_impact	0,37	neutral	0,86	neutral	0,96	deleterious	0,27	5,4	0,22	0,45	neutral	0,31	neutral	0,13	neutral	0,27	neutral	0,3	4	neutral	0,66	deleterious	0,65	neutral	-6	neutral	0,12	medium_impact	0,65	medium_impact	0,01	medium_impact	-0,77	0,32	0,8	15,65	9,34	N	0,47	N	0,04	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10336	10336	T	G	MI.15552	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	278	93	L	W	tTa/tGa	-8,7	0	0,02	possibly_damaging	0,89	neutral	0,24	neutral	0,73	deleterious	-4,84	deleterious	-2,53	medium_impact	2,88	neutral	0,75	neutral	0,37	deleterious	2,61	20,2	0,07	0,35	disease	0,66	neutral	0,49	neutral	0,46	disease	0,54	1	neutral	0,92	neutral	0,18	NA	0	deleterious	0,68	low_impact	-1,54	medium_impact	-0,09	medium_impact	1,53	0,15	0,8	15,65	9,34	N	0,36	N	0,4	polymorphism	1	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10336	10336	T	C	MI.15553	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	278	93	L	S	tTa/tCa	-8,7	0	0,02	benign	0,18	neutral	0,49	neutral	0,79	neutral	-2,54	neutral	-0,75	low_impact	1,29	neutral	0,86	neutral	0,98	deleterious	0,58	7,99	0,08	0,35	neutral	0,32	neutral	0,24	neutral	0,34	neutral	0,43	1	neutral	0,41	deleterious	0,66	neutral	-6	neutral	0,21	medium_impact	-0,12	medium_impact	0,18	medium_impact	0,07	0,22	0,8	15,65	9,34	N	0,39	N	0,17	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10337	10337	A	C	MI.15554	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	279	93	L	F	ttA/ttC	-2,24	0	0	benign	0,26	neutral	0,77	neutral	0,85	neutral	-1,39	neutral	-1,2	neutral_impact	0,71	neutral	0,81	neutral	0,96	deleterious	0,27	5,36	0,27	0,45	neutral	0,22	neutral	0,21	neutral	0,26	neutral	0,36	3	neutral	0,17	deleterious	0,76	neutral	-6	neutral	0,33	medium_impact	-0,31	medium_impact	0,48	medium_impact	-0,46	0,33	0,8	15,65	9,34	N	0,31	N	0,06	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10337	10337	A	T	MI.15555	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	279	93	L	F	ttA/ttT	-2,24	0	0	benign	0,26	neutral	0,77	neutral	0,85	neutral	-1,39	neutral	-1,2	neutral_impact	0,71	neutral	0,81	neutral	0,96	deleterious	0,35	6,12	0,27	0,45	neutral	0,22	neutral	0,21	neutral	0,26	neutral	0,36	3	neutral	0,17	deleterious	0,76	neutral	-6	neutral	0,33	medium_impact	-0,31	medium_impact	0,48	medium_impact	-0,46	0,33	0,8	15,65	9,34	N	0,3	N	0,06	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10338	10338	T	A	MI.15556	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	280	94	L	M	Tta/Ata	-8,24	0	0	probably_damaging	0,98	neutral	0,25	neutral	0,78	neutral	-2,35	neutral	-1,75	medium_impact	2,54	neutral	0,81	neutral	0,66	deleterious	3,53	23,1	0,13	0,4	neutral	0,41	neutral	0,32	neutral	0,41	neutral	0,47	1	deleterious	0,98	neutral	0,14	deleterious	1	deleterious	0,68	low_impact	-2,24	medium_impact	-0,08	medium_impact	1,22	0,32	0,8	NA	NA	N	0,4	N	0,6	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10338	10338	T	G	MI.15557	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	280	94	L	V	Tta/Gta	-8,24	0	0	possibly_damaging	0,86	neutral	0,23	neutral	0,81	neutral	-1,66	neutral	-2,35	low_impact	1,71	neutral	0,81	neutral	0,73	deleterious	1,91	15,67	0,15	0,4	neutral	0,25	neutral	0,2	neutral	0,27	neutral	0,38	2	neutral	0,9	neutral	0,19	neutral	-3	deleterious	0,61	low_impact	-1,43	medium_impact	-0,1	medium_impact	0,46	0,3	0,8	NA	NA	N	0,41	N	0,5	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10339	10339	T	G	MI.15558	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	281	94	L	W	tTa/tGa	-2,48	0	0	probably_damaging	0,99	neutral	0,06	neutral	0,72	deleterious	-5,25	deleterious	-5,36	high_impact	3,83	neutral	0,74	damaging	0,27	deleterious	3,78	23,4	0,04	0,35	disease	0,84	disease	0,66	disease	0,54	disease	0,66	3	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,78	low_impact	-2,52	medium_impact	-0,47	high_impact	2,4	0,12	0,8	NA	NA	N	0,37	N	0,83	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10339	10339	T	C	MI.15559	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	281	94	L	S	tTa/tCa	-2,48	0	0	probably_damaging	0,97	neutral	0,25	neutral	0,73	deleterious	-4,22	deleterious	-5,34	medium_impact	2,79	neutral	0,69	neutral	0,36	deleterious	3,83	23,4	0,05	0,35	disease	0,67	disease	0,53	disease	0,54	disease	0,63	3	neutral	0,98	neutral	0,14	deleterious	1	deleterious	0,74	low_impact	-2,08	medium_impact	-0,08	medium_impact	1,45	0,17	0,8	NA	NA	N	0,32	N	0,9	polymorphism	1	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8418	8418	T	C	MI.1556	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	53	18	L	P	cTt/cCt	-14,68	0	0	probably_damaging	1	deleterious	0,02	neutral	1,51	deleterious	-6,55	deleterious	-3,76	medium_impact	2,19	neutral	0,98	neutral	0,7	deleterious	2,55	19,82	0,32447288	0,85	disease	0,78	neutral	0,12	disease	0,56	neutral	0,06	9	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,77	low_impact	-3,6	medium_impact	-0,66	medium_impact	0,78	0,54	0,85	2,94	7,61	N	0,52	P	0,33	polymorphism	1	0,1	rs1057516062	Likely pathogenic	Optic_neuropathy	RCV000408923.1	Human_Phenotype_Ontology:MedGen	.	.	.	.	.	.	.	.	.	.
chrM	10340	10340	A	T	MI.15560	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	282	94	L	F	ttA/ttT	5,83	0,89	0	benign	0,17	neutral	0,49	neutral	1,66	neutral	2,06	deleterious	-3,55	neutral_impact	-0,1	neutral	0,82	neutral	0,68	deleterious	3,53	23,1	0,12	0,4	neutral	0,21	neutral	0,25	neutral	0,35	neutral	0,42	2	neutral	0,41	deleterious	0,66	neutral	-6	neutral	0,24	medium_impact	-0,1	medium_impact	0,18	low_impact	-1,2	0,22	0,8	NA	NA	N	0,5	N	0,27	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10340	10340	A	C	MI.15561	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	282	94	L	F	ttA/ttC	5,83	0,89	0	benign	0,17	neutral	0,49	neutral	1,66	neutral	2,06	deleterious	-3,55	neutral_impact	-0,1	neutral	0,82	neutral	0,68	deleterious	3,41	23	0,12	0,4	neutral	0,21	neutral	0,25	neutral	0,35	neutral	0,42	2	neutral	0,41	deleterious	0,66	neutral	-6	neutral	0,24	medium_impact	-0,1	medium_impact	0,18	low_impact	-1,2	0,22	0,8	NA	NA	N	0,49	N	0,27	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10341	10341	A	C	MI.15562	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	283	95	I	L	Atc/Ctc	-5,7	0	0	possibly_damaging	0,62	neutral	0,78	neutral	1,2	neutral	-0,02	neutral	-1,06	neutral_impact	0,66	neutral	0,73	neutral	0,91	neutral	1,64	14,07	0,15	0,4	neutral	0,11	neutral	0,21	neutral	0,28	neutral	0,36	3	neutral	0,54	deleterious	0,58	neutral	-3	neutral	0,4	medium_impact	-0,91	medium_impact	0,5	medium_impact	-0,5	0,31	0,8	NA	NA	N	0,33	N	0,64	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10341	10341	A	T	MI.15563	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	283	95	I	F	Atc/Ttc	-5,7	0	0	probably_damaging	0,96	neutral	0,71	neutral	0,86	neutral	-1,43	deleterious	-3,41	low_impact	0,96	neutral	0,73	damaging	0,23	deleterious	3,79	23,4	0,16	0,45	neutral	0,5	disease	0,71	neutral	0,5	disease	0,5	0	neutral	0,95	neutral	0,38	neutral	-2	deleterious	0,71	low_impact	-1,96	medium_impact	0,41	medium_impact	-0,23	0,29	0,8	NA	NA	N	0,18	N	0,89	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10341	10341	A	G	MI.15564	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	283	95	I	V	Atc/Gtc	-5,7	0	0	benign	0,18	neutral	0,59	neutral	1	neutral	-0,33	neutral	-0,67	low_impact	1,17	neutral	0,75	neutral	0,96	neutral	1,71	14,47	0,27	0,45	neutral	0,15	neutral	0,34	neutral	0,45	neutral	0,44	1	neutral	0,3	deleterious	0,71	neutral	-6	neutral	0,15	medium_impact	-0,12	medium_impact	0,28	medium_impact	-0,04	0,17	0,8	NA	NA	N	0,33	N	0,13	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10342	10342	T	G	MI.15565	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	284	95	I	S	aTc/aGc	0,06	0	0	probably_damaging	0,95	neutral	0,12	neutral	0,84	neutral	-2,91	deleterious	-5,04	medium_impact	3,11	neutral	0,61	damaging	0,11	deleterious	4,32	24	0,05	0,35	disease	0,67	disease	0,75	disease	0,64	disease	0,71	4	neutral	0,98	neutral	0,09	deleterious	1	deleterious	0,74	low_impact	-1,87	medium_impact	-0,29	medium_impact	1,74	0,23	0,8	NA	NA	N	0,29	N	0,94	polymorphism	1	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10342	10342	T	A	MI.15566	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	284	95	I	N	aTc/aAc	0,06	0	0	probably_damaging	0,98	deleterious	0,01	neutral	0,8	deleterious	-4,12	deleterious	-6,01	medium_impact	3,21	neutral	0,6	damaging	0,11	deleterious	4,62	24,5	0,1	0,4	disease	0,8	disease	0,74	disease	0,67	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,76	low_impact	-2,24	medium_impact	-0,92	medium_impact	1,83	0,31	0,8	NA	NA	N	0,26	N	0,99	polymorphism	1	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10342	10342	T	C	MI.15567	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	284	95	I	T	aTc/aCc	0,06	0	0	possibly_damaging	0,86	neutral	0,1	neutral	0,86	neutral	-2,33	deleterious	-4,01	medium_impact	2,69	neutral	0,76	damaging	0,22	deleterious	3,51	23,1	0,12	0,4	disease	0,53	neutral	0,47	disease	0,63	disease	0,6	2	neutral	0,95	neutral	0,12	NA	0	deleterious	0,63	low_impact	-1,43	medium_impact	-0,34	medium_impact	1,36	0,28	0,8	NA	NA	N	0,33	N	0,9	polymorphism	1	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10343	10343	C	A	MI.15568	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	285	95	I	M	atC/atA	5,83	0,89	0	probably_damaging	0,98	neutral	0,31	neutral	0,85	neutral	-1,73	neutral	-2,1	medium_impact	2,21	neutral	0,72	damaging	0,2	deleterious	3,93	23,5	0,23	0,45	neutral	0,44	disease	0,54	neutral	0,43	neutral	0,49	0	deleterious	0,98	neutral	0,17	deleterious	1	deleterious	0,67	low_impact	-2,24	medium_impact	0	medium_impact	0,92	0,37	0,8	NA	NA	N	0,47	N	0,58	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10343	10343	C	G	MI.15569	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	285	95	I	M	atC/atG	5,83	0,89	0	probably_damaging	0,98	neutral	0,31	neutral	0,85	neutral	-1,73	neutral	-2,1	medium_impact	2,21	neutral	0,72	damaging	0,2	deleterious	3,43	23	0,23	0,45	neutral	0,44	disease	0,54	neutral	0,43	neutral	0,49	0	deleterious	0,98	neutral	0,17	deleterious	1	deleterious	0,67	low_impact	-2,24	medium_impact	0	medium_impact	0,92	0,37	0,8	NA	NA	N	0,47	N	0,58	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8418	8418	T	G	MI.1557	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	53	18	L	R	cTt/cGt	-14,68	0	0	probably_damaging	1	deleterious	0,04	neutral	1,51	deleterious	-6,18	deleterious	-4,42	medium_impact	3,4	neutral	1	neutral	0,41	deleterious	3,95	23,6	0,23173347	0,85	disease	0,71	disease	0,55	disease	0,69	disease	0,6	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,83	low_impact	-3,6	medium_impact	-0,49	medium_impact	1,82	0,66	0,85	2,94	7,61	N	0,53	P	0,68	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10344	10344	A	C	MI.15570	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	286	96	I	L	Atc/Ctc	-13,77	0	0,01	benign	0,08	neutral	1	neutral	1,12	neutral	0,77	neutral	-0,23	neutral_impact	-0,56	neutral	0,83	neutral	0,97	deleterious	0,34	6,11	0,2	0,45	neutral	0,11	neutral	0,24	neutral	0,26	neutral	0,41	2	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,11	medium_impact	0,24	high_impact	1,85	low_impact	-1,62	0,47	0,8	18,26	11,99	N	0,29	N	0,14	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10344	10344	A	T	MI.15571	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	286	96	I	F	Atc/Ttc	-13,77	0	0,01	possibly_damaging	0,56	neutral	0,66	neutral	0,91	neutral	-0,99	neutral	-1,32	neutral_impact	0,78	neutral	0,85	neutral	0,97	neutral	0,89	10,03	0,17	0,45	neutral	0,32	neutral	0,47	neutral	0,32	neutral	0,46	1	neutral	0,48	deleterious	0,55	neutral	-3	deleterious	0,45	medium_impact	-0,81	medium_impact	0,35	medium_impact	-0,39	0,33	0,8	18,26	11,99	N	0,3	N	0,44	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10344	10344	A	G	MI.15572	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	286	96	I	V	Atc/Gtc	-13,77	0	0,01	benign	0,01	neutral	0,23	neutral	1,06	neutral	0,41	neutral	-0,16	neutral_impact	0,58	neutral	0,83	neutral	0,81	neutral	-0,79	0,05	0,37	0,5	neutral	0,15	neutral	0,17	neutral	0,3	neutral	0,3	4	neutral	0,76	deleterious	0,61	neutral	-6	neutral	0,09	medium_impact	1,09	medium_impact	-0,1	medium_impact	-0,58	0,41	0,8	18,26	11,99	N	0,43	N	0,43	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10345	10345	T	A	MI.15573	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	287	96	I	N	aTc/aAc	-4,32	0	0,06	benign	0,4	neutral	0,09	neutral	0,84	neutral	-2,95	neutral	-1,43	medium_impact	3,25	neutral	0,72	neutral	0,36	deleterious	2,6	20,2	0,11	0,4	neutral	0,42	disease	0,58	disease	0,56	disease	0,67	3	neutral	0,9	neutral	0,35	neutral	-3	neutral	0,37	medium_impact	-0,56	medium_impact	-0,37	medium_impact	1,87	0,25	0,8	18,26	11,99	N	0,39	N	0,5	polymorphism	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10345	10345	T	G	MI.15574	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	287	96	I	S	aTc/aGc	-4,32	0	0,06	benign	0,19	neutral	0,16	neutral	0,91	neutral	-1,03	neutral	0,24	neutral_impact	0,29	neutral	0,8	neutral	1	deleterious	0,4	6,62	0,06	0,35	neutral	0,2	neutral	0,42	neutral	0,35	neutral	0,43	1	neutral	0,81	deleterious	0,49	neutral	-6	neutral	0,18	medium_impact	-0,15	medium_impact	-0,21	medium_impact	-0,84	0,31	0,8	18,26	11,99	N	0,38	N	0,13	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10345	10345	T	C	MI.15575	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	287	96	I	T	aTc/aCc	-4,32	0	0,06	benign	0,01	neutral	0,15	neutral	0,92	neutral	-1,03	neutral	0,16	neutral_impact	0,76	neutral	0,9	neutral	0,99	neutral	-0,13	1,5	0,15	0,4	neutral	0,14	neutral	0,19	neutral	0,32	neutral	0,35	3	neutral	0,85	deleterious	0,57	neutral	-6	neutral	0,09	medium_impact	1,09	medium_impact	-0,23	medium_impact	-0,41	0,34	0,8	18,26	11,99	N	0,4	N	0,06	polymorphism	1	0,2	rs201397417	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10346	10346	C	G	MI.15576	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	288	96	I	M	atC/atG	-2,01	0	0	possibly_damaging	0,71	neutral	0,1	neutral	0,9	neutral	-1,25	neutral	-0,18	low_impact	1,3	neutral	0,8	neutral	0,87	deleterious	0,52	7,56	0,26	0,45	neutral	0,32	neutral	0,27	neutral	0,3	neutral	0,45	1	neutral	0,92	neutral	0,2	neutral	-3	deleterious	0,47	low_impact	-1,07	medium_impact	-0,34	medium_impact	0,08	0,38	0,8	18,26	11,99	N	0,46	N	0,48	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10346	10346	C	A	MI.15577	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	288	96	I	M	atC/atA	-2,01	0	0	possibly_damaging	0,71	neutral	0,1	neutral	0,9	neutral	-1,25	neutral	-0,18	low_impact	1,3	neutral	0,8	neutral	0,87	neutral	1,04	10,9	0,26	0,45	neutral	0,32	neutral	0,27	neutral	0,3	neutral	0,45	1	neutral	0,92	neutral	0,2	neutral	-3	deleterious	0,47	low_impact	-1,07	medium_impact	-0,34	medium_impact	0,08	0,38	0,8	18,26	11,99	N	0,46	N	0,48	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10347	10347	A	C	MI.15578	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	289	97	I	L	Atc/Ctc	-20	0	0	probably_damaging	0,99	neutral	1	neutral	0,96	neutral	-0,21	neutral	-0,52	neutral_impact	0,74	neutral	0,75	neutral	0,96	neutral	1,1	11,22	0,17	0,45	neutral	0,09	neutral	0,18	neutral	0,25	neutral	0,27	5	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,62	low_impact	-2,52	high_impact	1,85	medium_impact	-0,43	0,23	0,8	13,91	12,04	N	0,31	N	0,05	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10347	10347	A	T	MI.15579	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	289	97	I	F	Atc/Ttc	-20	0	0	probably_damaging	1	neutral	0,38	neutral	0,85	neutral	-1,18	deleterious	-3,04	medium_impact	2,41	neutral	0,75	neutral	0,76	deleterious	3,79	23,4	0,13	0,4	neutral	0,47	disease	0,73	disease	0,55	disease	0,61	2	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,75	low_impact	-3,43	medium_impact	0,07	medium_impact	1,1	0,25	0,8	13,91	12,04	N	0,36	N	0,61	polymorphism	1	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8418	8418	T	A	MI.1558	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	53	18	L	H	cTt/cAt	-14,68	0	0	probably_damaging	1	neutral	0,06	neutral	1,5	deleterious	-6,87	deleterious	-5,03	medium_impact	3,4	neutral	0,99	neutral	0,45	deleterious	3,92	23,5	0,25207871	0,85	disease	0,79	neutral	0,4	disease	0,65	neutral	0,25	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	-0,38	medium_impact	1,82	0,57	0,85	2,94	7,61	N	0,53	P	0,62	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10347	10347	A	G	MI.15580	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	289	97	I	V	Atc/Gtc	-20	0	0	probably_damaging	0,99	neutral	0,2	neutral	0,93	neutral	-0,39	neutral	-0,76	low_impact	1,16	neutral	0,81	neutral	0,9	deleterious	1,94	15,82	0,33	0,5	neutral	0,13	neutral	0,34	neutral	0,4	neutral	0,44	1	deleterious	0,99	neutral	0,11	neutral	-2	deleterious	0,61	low_impact	-2,52	medium_impact	-0,14	medium_impact	-0,05	0,23	0,8	13,91	12,04	N	0,36	N	0,1	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10348	10348	T	C	MI.15581	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	290	97	I	T	aTc/aCc	-0,4	0	0	probably_damaging	1	neutral	0,17	neutral	0,81	neutral	-1,68	deleterious	-3,63	medium_impact	2,8	neutral	0,78	neutral	0,6	deleterious	3,47	23	0,12	0,4	disease	0,51	neutral	0,47	disease	0,54	disease	0,52	0	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,7	low_impact	-3,43	medium_impact	-0,19	medium_impact	1,46	0,23	0,8	13,91	12,04	N	0,39	N	0,78	polymorphism	1	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10348	10348	T	G	MI.15582	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	290	97	I	S	aTc/aGc	-0,4	0	0	probably_damaging	1	deleterious	0,04	neutral	0,77	neutral	-2,44	deleterious	-4,58	medium_impact	3,29	neutral	0,69	neutral	0,41	deleterious	4,35	24,1	0,06	0,35	disease	0,65	disease	0,75	disease	0,59	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,77	low_impact	-3,43	medium_impact	-0,58	medium_impact	1,91	0,15	0,8	13,91	12,04	N	0,38	N	0,86	polymorphism	1	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10348	10348	T	A	MI.15583	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	290	97	I	N	aTc/aAc	-0,4	0	0	probably_damaging	1	deleterious	0,02	neutral	0,74	deleterious	-3,68	deleterious	-5,61	high_impact	3,72	neutral	0,65	neutral	0,41	deleterious	4,52	24,3	0,11	0,4	disease	0,78	disease	0,8	disease	0,6	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-3,43	medium_impact	-0,75	high_impact	2,3	0,19	0,8	13,91	12,04	N	0,33	N	0,89	polymorphism	1	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10349	10349	C	G	MI.15584	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	291	97	I	M	atC/atG	5,83	0,89	0	probably_damaging	1	neutral	0,13	neutral	0,83	neutral	-1,35	neutral	-1,71	medium_impact	2,83	neutral	0,75	neutral	0,67	deleterious	3,39	23	0,25	0,45	neutral	0,42	disease	0,52	disease	0,52	disease	0,51	0	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,69	low_impact	-3,43	medium_impact	-0,27	medium_impact	1,49	0,28	0,8	13,91	12,04	P	0,53	P	0,62	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10349	10349	C	A	MI.15585	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	291	97	I	M	atC/atA	5,83	0,89	0	probably_damaging	1	neutral	0,13	neutral	0,83	neutral	-1,35	neutral	-1,71	medium_impact	2,83	neutral	0,75	neutral	0,67	deleterious	3,87	23,5	0,25	0,45	neutral	0,42	disease	0,52	disease	0,52	disease	0,51	0	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,69	low_impact	-3,43	medium_impact	-0,27	medium_impact	1,49	0,28	0,8	13,91	12,04	P	0,54	P	0,62	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10350	10350	C	G	MI.15586	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	292	98	L	V	Cta/Gta	-8,24	0	0	probably_damaging	1	neutral	0,21	neutral	0,39	neutral	-2,57	deleterious	-2,89	medium_impact	3,38	damaging	0,57	damaging	0,1	deleterious	3,45	23	0,15	0,4	neutral	0,25	neutral	0,49	disease	0,63	disease	0,54	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,69	low_impact	-3,43	medium_impact	-0,13	medium_impact	1,99	0,41	0,8	1,74	6,79	N	0,33	N	0,89	polymorphism	1	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10350	10350	C	A	MI.15587	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	292	98	L	M	Cta/Ata	-8,24	0	0	probably_damaging	1	neutral	0,09	neutral	0,32	deleterious	-3,5	neutral	-1,92	high_impact	3,87	neutral	0,63	damaging	0,1	deleterious	3,74	23,3	0,15	0,4	neutral	0,48	neutral	0,47	disease	0,62	neutral	0,45	1	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,71	low_impact	-3,43	medium_impact	-0,37	high_impact	2,44	0,39	0,8	1,74	6,79	N	0,37	N	0,91	polymorphism	1	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10351	10351	T	G	MI.15588	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	293	98	L	R	cTa/cGa	-0,63	0	0	probably_damaging	1	deleterious	0,02	neutral	0,25	deleterious	-5,7	deleterious	-5,74	high_impact	4,91	damaging	0,55	damaging	0,03	deleterious	4,22	23,9	0,02	0,35	disease	0,8	disease	0,81	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-3,43	medium_impact	-0,75	high_impact	3,39	0,09	0,8	1,74	6,79	P	0,6	P	1	polymorphism	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10351	10351	T	C	MI.15589	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	293	98	L	P	cTa/cCa	-0,63	0	0	probably_damaging	1	deleterious	0,01	neutral	0,3	deleterious	-3,7	deleterious	-6,67	high_impact	4,55	damaging	0,47	damaging	0,04	deleterious	3,96	23,6	0,02	0,35	disease	0,85	disease	0,75	disease	0,77	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,43	medium_impact	-0,92	high_impact	3,06	0,2	0,8	1,74	6,79	P	0,5	N	0,99	polymorphism	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8420	8420	A	T	MI.1559	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	55	19	T	S	Aca/Tca	-10,05	0	0	probably_damaging	0,97	neutral	0,18	neutral	2,02	neutral	0,12	deleterious	-3,02	medium_impact	2,04	neutral	1	neutral	0,77	deleterious	3,05	22,4	0,59098804	0,85	disease	0,57	neutral	0,15	neutral	0,48	neutral	0,1	8	deleterious	0,98	neutral	0,11	deleterious	1	deleterious	0,7	low_impact	-2,19	medium_impact	-0,08	medium_impact	0,65	0,63	0,85	NA	NA	P	0,55	P	0,08	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10351	10351	T	A	MI.15590	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	293	98	L	Q	cTa/cAa	-0,63	0	0	probably_damaging	1	deleterious	0,02	neutral	0,25	deleterious	-5,77	deleterious	-5,73	high_impact	4,55	damaging	0,55	damaging	0,05	deleterious	4,12	23,8	0,03	0,35	disease	0,8	disease	0,69	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-3,43	medium_impact	-0,75	high_impact	3,06	0,23	0,8	1,74	6,79	N	0,37	N	0,97	polymorphism	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10353	10353	G	C	MI.15591	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	295	99	A	P	Gcc/Ccc	-0,63	0	0	possibly_damaging	0,58	deleterious	0,02	neutral	0,88	neutral	-2,83	deleterious	-3,11	medium_impact	3,46	neutral	0,64	neutral	0,32	deleterious	2,27	17,96	0,07	0,35	disease	0,51	disease	0,9	disease	0,66	disease	0,81	6	neutral	0,98	neutral	0,22	deleterious	4	deleterious	0,64	medium_impact	-0,84	medium_impact	-0,75	high_impact	2,06	0,48	0,8	12,17	9,19	N	0,36	N	0,75	polymorphism	1	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10353	10353	G	A	MI.15592	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	295	99	A	T	Gcc/Acc	-0,63	0	0	benign	0,01	neutral	0,14	neutral	0,97	neutral	-0,39	neutral	-0,51	neutral_impact	0,26	neutral	0,84	neutral	0,9	neutral	-0,37	0,45	0,22	0,45	neutral	0,12	neutral	0,06	neutral	0,25	neutral	0,22	6	neutral	0,86	deleterious	0,57	neutral	-6	neutral	0,09	medium_impact	1,09	medium_impact	-0,25	medium_impact	-0,87	0,63	0,8	12,17	9,19	N	0,49	N	0,16	polymorphism	1	0,16	rs28435660	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10353	10353	G	T	MI.15593	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	295	99	A	S	Gcc/Tcc	-0,63	0	0	benign	0,2	neutral	0,1	neutral	0,95	neutral	-0,59	neutral	-0,83	low_impact	1,26	neutral	0,79	neutral	0,88	deleterious	0,7	8,81	0,3	0,45	neutral	0,21	disease	0,54	neutral	0,33	neutral	0,45	1	neutral	0,88	neutral	0,45	neutral	-6	neutral	0,21	medium_impact	-0,17	medium_impact	-0,34	medium_impact	0,05	0,36	0,8	12,17	9,19	N	0,4	N	0,25	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10354	10354	C	G	MI.15594	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	296	99	A	G	gCc/gGc	0,29	0	0	benign	0,29	neutral	0,18	neutral	0,89	neutral	-2,3	deleterious	-2,8	low_impact	1,86	neutral	0,78	neutral	0,65	deleterious	2,16	17,22	0,25	0,45	neutral	0,38	disease	0,6	neutral	0,42	neutral	0,47	1	neutral	0,79	neutral	0,45	neutral	-6	neutral	0,27	medium_impact	-0,37	medium_impact	-0,18	medium_impact	0,6	0,54	0,8	12,17	9,19	N	0,37	N	0,39	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10354	10354	C	A	MI.15595	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	296	99	A	D	gCc/gAc	0,29	0	0	possibly_damaging	0,5	deleterious	0,02	neutral	0,88	deleterious	-3,34	deleterious	-3,48	medium_impact	3,46	neutral	0,62	neutral	0,31	deleterious	3,03	22,3	0,05	0,35	neutral	0,46	disease	0,87	disease	0,64	disease	0,8	6	neutral	0,98	neutral	0,26	deleterious	4	neutral	0,43	medium_impact	-0,72	medium_impact	-0,75	high_impact	2,06	0,24	0,8	12,17	9,19	N	0,38	N	0,8	polymorphism	1	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10354	10354	C	T	MI.15596	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	296	99	A	V	gCc/gTc	0,29	0	0	benign	0,02	neutral	0,11	neutral	1,07	neutral	0,67	neutral	-2,17	low_impact	0,93	neutral	0,78	neutral	0,62	deleterious	2,51	19,56	0,2	0,45	neutral	0,29	disease	0,64	neutral	0,36	neutral	0,48	0	neutral	0,89	deleterious	0,55	neutral	-6	neutral	0,17	medium_impact	0,81	medium_impact	-0,31	medium_impact	-0,26	0,62	0,8	12,17	9,19	N	0,36	N	0,43	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10356	10356	C	A	MI.15597	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	298	100	L	M	Cta/Ata	-7,55	0	0	probably_damaging	1	neutral	0,15	neutral	0,81	neutral	-2,37	neutral	-1,44	low_impact	1,92	neutral	0,81	neutral	0,87	deleterious	3,8	23,4	0,32	0,5	neutral	0,33	neutral	0,4	neutral	0,37	neutral	0,45	1	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,67	low_impact	-3,43	medium_impact	-0,23	medium_impact	0,65	0,54	0,8	5,22	9,73	N	0,41	N	0,54	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10356	10356	C	G	MI.15598	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	298	100	L	V	Cta/Gta	-7,55	0	0	probably_damaging	1	neutral	0,27	neutral	0,98	neutral	0,53	neutral	-1,83	low_impact	1,38	neutral	0,85	neutral	0,93	deleterious	2,39	18,75	0,3	0,45	neutral	0,18	neutral	0,38	neutral	0,34	neutral	0,43	1	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,66	low_impact	-3,43	medium_impact	-0,05	medium_impact	0,16	0,45	0,8	5,22	9,73	N	0,33	N	0,22	polymorphism	1	0,26	rs28457866	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10357	10357	T	A	MI.15599	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	299	100	L	Q	cTa/cAa	-1,32	0	0	probably_damaging	1	neutral	0,1	neutral	0,75	deleterious	-3,46	deleterious	-4,58	high_impact	4,21	neutral	0,71	neutral	0,46	deleterious	4,14	23,8	0,06	0,35	disease	0,51	disease	0,71	disease	0,62	disease	0,67	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,73	low_impact	-3,43	medium_impact	-0,34	high_impact	2,75	0,18	0,8	5,22	9,73	N	0,47	N	0,82	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8599	8599	C	G	MI.156	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	73	25	L	V	Cta/Gta	-4,27	0	0	probably_damaging	0,99	neutral	0,26	neutral	4,35	neutral	-0,27	neutral	-1,05	low_impact	0,92	neutral	0,88	neutral	0,86	deleterious	1,84	15,24	0,47	0,65	neutral	0,48	neutral	0,21	neutral	0,35	neutral	0,35	3	deleterious	0,99	neutral	0,14	neutral	-2	deleterious	0,7	low_impact	-2,65	medium_impact	0,04	medium_impact	-0,31	0,7	0,9	10,18	13,06	N	0,43	N	0,3	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8420	8420	A	G	MI.1560	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	55	19	T	A	Aca/Gca	-10,05	0	0	probably_damaging	0,97	neutral	0,42	neutral	1,86	neutral	-1,17	deleterious	-3,31	low_impact	1,22	neutral	1	neutral	0,97	deleterious	1,84	15,25	0,64287435	0,85	disease	0,52	neutral	0,05	neutral	0,5	neutral	0,03	9	neutral	0,97	neutral	0,23	neutral	-2	deleterious	0,7	low_impact	-2,19	medium_impact	0,21	medium_impact	-0,05	0,38	0,85	NA	NA	N	0,46	N	0,25	polymorphism	1	0,13	rs375408733	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10357	10357	T	C	MI.15600	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	299	100	L	P	cTa/cCa	-1,32	0	0	probably_damaging	1	neutral	0,07	neutral	0,74	deleterious	-3,94	deleterious	-5,32	high_impact	4,21	damaging	0,6	neutral	0,33	deleterious	3,97	23,6	0,05	0,35	disease	0,58	disease	0,85	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,82	low_impact	-3,43	medium_impact	-0,43	high_impact	2,75	0,27	0,8	5,22	9,73	N	0,4	N	0,93	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10357	10357	T	G	MI.15601	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	299	100	L	R	cTa/cGa	-1,32	0	0	probably_damaging	1	neutral	0,11	neutral	0,75	deleterious	-3,32	deleterious	-4,63	high_impact	4,21	neutral	0,64	neutral	0,38	deleterious	4,22	23,9	0,04	0,35	neutral	0,49	disease	0,84	disease	0,74	disease	0,77	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,81	low_impact	-3,43	medium_impact	-0,31	high_impact	2,75	0,17	0,8	5,22	9,73	N	0,46	N	0,85	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10359	10359	A	G	MI.15602	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	301	101	S	G	Agt/Ggt	-9,62	0	0	benign	0,02	neutral	0,3	neutral	1,52	neutral	2,21	neutral	2,8	neutral_impact	-1,92	neutral	0,86	neutral	0,95	neutral	-1,03	0,01	0,12	0,4	neutral	0,09	neutral	0,09	neutral	0,35	neutral	0,22	6	neutral	0,69	deleterious	0,64	neutral	-6	neutral	0,1	medium_impact	0,81	medium_impact	-0,01	low_impact	-2,87	0,49	0,8	NA	NA	N	0,37	N	0,02	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10359	10359	A	T	MI.15603	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	301	101	S	C	Agt/Tgt	-9,62	0	0	probably_damaging	0,96	neutral	0,05	neutral	0,84	deleterious	-3,71	deleterious	-3,51	medium_impact	2,42	neutral	0,62	neutral	0,37	deleterious	3,39	23	0,05	0,35	disease	0,66	disease	0,77	disease	0,54	disease	0,72	4	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,8	low_impact	-1,96	medium_impact	-0,52	medium_impact	1,11	0,27	0,8	NA	NA	N	0,29	N	0,7	polymorphism	1	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10359	10359	A	C	MI.15604	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	301	101	S	R	Agt/Cgt	-9,62	0	0	possibly_damaging	0,89	neutral	0,09	neutral	0,85	neutral	-2,78	deleterious	-2,84	medium_impact	2,76	neutral	0,63	neutral	0,44	deleterious	3,63	23,2	0,03	0,35	disease	0,59	disease	0,93	disease	0,69	disease	0,82	6	neutral	0,97	neutral	0,1	NA	0	deleterious	0,85	low_impact	-1,54	medium_impact	-0,37	medium_impact	1,42	0,29	0,8	NA	NA	N	0,34	N	0,69	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10360	10360	G	A	MI.15605	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	302	101	S	N	aGt/aAt	2,37	0,99	0	possibly_damaging	0,61	neutral	0,13	neutral	0,86	neutral	-2,52	neutral	-0,9	medium_impact	2,76	neutral	0,66	neutral	0,54	deleterious	1,94	15,84	0,27	0,45	neutral	0,49	disease	0,83	disease	0,55	disease	0,77	5	neutral	0,87	neutral	0,26	NA	0	deleterious	0,68	medium_impact	-0,89	medium_impact	-0,27	medium_impact	1,42	0,35	0,8	NA	NA	P	0,56	P	0,41	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10360	10360	G	T	MI.15606	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	302	101	S	I	aGt/aTt	2,37	0,99	0	probably_damaging	0,92	neutral	0,39	neutral	0,85	neutral	-2,99	deleterious	-4,43	medium_impact	2,06	neutral	0,7	neutral	0,45	deleterious	3,92	23,5	0,04	0,35	disease	0,66	disease	0,87	disease	0,57	disease	0,79	6	neutral	0,92	neutral	0,24	deleterious	1	deleterious	0,84	low_impact	-1,68	medium_impact	0,08	medium_impact	0,78	0,25	0,8	NA	NA	N	0,44	N	0,85	polymorphism	1	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10360	10360	G	C	MI.15607	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	302	101	S	T	aGt/aCt	2,37	0,99	0	possibly_damaging	0,68	neutral	0,15	neutral	0,92	neutral	-0,87	neutral	-2,23	low_impact	1,72	neutral	0,68	neutral	0,53	neutral	1,78	14,87	0,17	0,45	neutral	0,36	neutral	0,5	disease	0,55	disease	0,67	3	neutral	0,87	neutral	0,24	neutral	-3	deleterious	0,63	low_impact	-1,01	medium_impact	-0,23	medium_impact	0,47	0,5	0,8	NA	NA	P	0,55	P	0,52	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10362	10362	C	G	MI.15608	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	304	102	L	V	Ctg/Gtg	-10,78	0	0	probably_damaging	1	neutral	0,51	neutral	0,72	neutral	-1,32	deleterious	-2,9	medium_impact	3,17	neutral	0,67	damaging	0,08	deleterious	3,51	23,1	0,24	0,45	disease	0,5	disease	0,55	disease	0,65	disease	0,55	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,76	low_impact	-3,43	medium_impact	0,2	medium_impact	1,8	0,49	0,8	NA	NA	N	0,25	N	0,89	polymorphism	1	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10362	10362	C	A	MI.15609	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	304	102	L	M	Ctg/Atg	-10,78	0	0	probably_damaging	1	neutral	0,22	neutral	0,58	deleterious	-3,19	neutral	-1,93	high_impact	3,69	neutral	0,75	damaging	0,12	deleterious	3,79	23,4	0,23	0,45	disease	0,59	disease	0,55	disease	0,69	disease	0,57	1	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,75	low_impact	-3,43	medium_impact	-0,12	high_impact	2,28	0,41	0,8	NA	NA	N	0,35	N	0,91	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8420	8420	A	C	MI.1561	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	55	19	T	P	Aca/Cca	-10,05	0	0	probably_damaging	0,99	neutral	0,07	neutral	1,75	deleterious	-4,64	deleterious	-4,98	high_impact	3,56	neutral	0,99	neutral	0,29	deleterious	3,3	22,9	0,25879581	0,85	disease	0,79	neutral	0,44	disease	0,76	neutral	0,34	3	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,81	low_impact	-2,65	medium_impact	-0,34	medium_impact	1,95	0,49	0,85	NA	NA	N	0,53	P	0,78	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10363	10363	T	G	MI.15610	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	305	102	L	R	cTg/cGg	-0,17	0	0	probably_damaging	1	neutral	0,34	neutral	0,54	deleterious	-4,53	deleterious	-5,79	high_impact	4,66	neutral	0,64	damaging	0,04	deleterious	4,22	23,9	0,01	0,35	disease	0,83	disease	0,87	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,43	medium_impact	0,03	high_impact	3,16	0,12	0,8	NA	NA	P	0,58	P	1	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10363	10363	T	A	MI.15611	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	305	102	L	Q	cTg/cAg	-0,17	0	0	probably_damaging	1	neutral	0,29	neutral	0,54	deleterious	-4,66	deleterious	-5,79	high_impact	4,66	neutral	0,66	damaging	0,05	deleterious	4,1	23,7	0,03	0,35	disease	0,85	disease	0,77	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,82	low_impact	-3,43	medium_impact	-0,03	high_impact	3,16	0,31	0,8	NA	NA	N	0,48	N	0,97	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10363	10363	T	C	MI.15612	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	305	102	L	P	cTg/cCg	-0,17	0	0	probably_damaging	1	neutral	0,2	neutral	0,53	deleterious	-5,11	deleterious	-6,75	high_impact	4,66	damaging	0,57	damaging	0,05	deleterious	4,01	23,6	0,02	0,35	disease	0,87	disease	0,83	disease	0,8	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,43	medium_impact	-0,14	high_impact	3,16	0,37	0,8	NA	NA	P	0,52	P	0,99	polymorphism	1	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10365	10365	G	C	MI.15613	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	307	103	A	P	Gcc/Ccc	-3,17	0	0	possibly_damaging	0,86	neutral	0,19	neutral	0,9	neutral	-2,67	deleterious	-4,02	high_impact	3,71	damaging	0,6	neutral	0,29	deleterious	3,63	23,2	0,05	0,35	disease	0,52	disease	0,91	disease	0,7	disease	0,8	6	neutral	0,92	neutral	0,17	deleterious	1	deleterious	0,79	low_impact	-1,43	medium_impact	-0,16	high_impact	2,29	0,6	0,8	NA	NA	N	0,39	N	0,8	polymorphism	1	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10365	10365	G	A	MI.15614	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	307	103	A	T	Gcc/Acc	-3,17	0	0	benign	0,03	neutral	0,41	neutral	0,95	neutral	-0,76	deleterious	-2,54	medium_impact	2,4	neutral	0,88	neutral	0,85	neutral	1,18	11,66	0,17	0,45	neutral	0,28	neutral	0,48	neutral	0,38	neutral	0,47	1	neutral	0,56	deleterious	0,69	neutral	-3	neutral	0,16	medium_impact	0,65	medium_impact	0,1	medium_impact	1,09	0,75	0,85	NA	NA	N	0,4	N	0,03	polymorphism	1	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10365	10365	G	T	MI.15615	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	307	103	A	S	Gcc/Tcc	-3,17	0	0	benign	0,4	neutral	0,39	neutral	0,95	neutral	-0,81	neutral	-2,23	medium_impact	3,37	neutral	0,78	neutral	0,69	deleterious	1,99	16,16	0,22	0,45	neutral	0,25	disease	0,59	neutral	0,46	neutral	0,48	0	neutral	0,55	deleterious	0,5	neutral	-3	neutral	0,36	medium_impact	-0,56	medium_impact	0,08	medium_impact	1,98	0,52	0,8	NA	NA	N	0,39	N	0,23	polymorphism	1	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10366	10366	C	G	MI.15616	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	308	103	A	G	gCc/gGc	0,06	0	0	benign	0,03	neutral	0,41	neutral	0,92	neutral	-1,77	deleterious	-3,49	medium_impact	2,82	neutral	0,78	neutral	0,56	deleterious	2,36	18,59	0,2	0,45	neutral	0,43	disease	0,62	disease	0,54	disease	0,68	4	neutral	0,56	deleterious	0,69	neutral	-3	neutral	0,2	medium_impact	0,65	medium_impact	0,1	medium_impact	1,48	0,71	0,85	NA	NA	N	0,32	N	0,44	polymorphism	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10366	10366	C	A	MI.15617	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	308	103	A	D	gCc/gAc	0,06	0	0	possibly_damaging	0,73	neutral	0,19	neutral	0,9	deleterious	-3,2	deleterious	-4,81	high_impact	3,71	neutral	0,67	neutral	0,33	deleterious	4,31	24	0,04	0,35	neutral	0,46	disease	0,87	disease	0,68	disease	0,79	6	neutral	0,86	neutral	0,23	deleterious	1	deleterious	0,73	low_impact	-1,11	medium_impact	-0,16	high_impact	2,29	0,42	0,8	NA	NA	N	0,42	N	0,96	polymorphism	1	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10366	10366	C	T	MI.15618	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	308	103	A	V	gCc/gTc	0,06	0	0	benign	0,08	neutral	0,5	neutral	1,1	neutral	0,92	neutral	-2,45	low_impact	1,34	neutral	0,75	neutral	0,64	neutral	1,06	11	0,17	0,45	neutral	0,22	neutral	0,41	neutral	0,34	neutral	0,43	1	neutral	0,43	deleterious	0,71	neutral	-6	neutral	0,17	medium_impact	0,24	medium_impact	0,19	medium_impact	0,12	0,7	0,85	NA	NA	N	0,37	N	0,51	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10368	10368	T	C	MI.15619	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	310	104	Y	H	Tat/Cat	-10,32	0	0	probably_damaging	1	neutral	0,42	neutral	0,49	deleterious	-5,75	deleterious	-4,82	medium_impact	2,32	damaging	0,57	damaging	0,07	deleterious	3,68	23,3	0,09	0,35	neutral	0,35	disease	0,69	disease	0,59	neutral	0,47	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,79	low_impact	-3,43	medium_impact	0,11	medium_impact	1,02	0,12	0,8	NA	NA	N	0,21	N	0,98	polymorphism	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8421	8421	C	T	MI.1562	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	56	19	T	M	aCa/aTa	-0,8	0	0	probably_damaging	1	neutral	0,11	neutral	1,83	neutral	-1,52	deleterious	-4,83	medium_impact	2,87	neutral	1	neutral	0,36	deleterious	3,78	23,4	0,47136521	0,85	disease	0,87	neutral	0,24	disease	0,63	neutral	0,15	7	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	-0,22	medium_impact	1,36	0,72	0,85	NA	NA	P	0,55	P	0,76	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10368	10368	T	A	MI.15620	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	310	104	Y	N	Tat/Aat	-10,32	0	0	probably_damaging	1	neutral	0,23	neutral	0,43	deleterious	-7,34	deleterious	-8,69	high_impact	4	damaging	0,6	damaging	0,04	deleterious	4,15	23,8	0,08	0,35	disease	0,73	disease	0,9	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	-0,1	high_impact	2,56	0,05	0,8	NA	NA	N	0,33	N	0,99	polymorphism	1	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10368	10368	T	G	MI.15621	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	310	104	Y	D	Tat/Gat	-10,32	0	0	probably_damaging	1	neutral	0,15	neutral	0,42	deleterious	-8,41	deleterious	-9,65	high_impact	4,7	damaging	0,58	damaging	0,04	deleterious	4,1	23,7	0,05	0,35	disease	0,79	disease	0,91	disease	0,68	disease	0,75	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,88	low_impact	-3,43	medium_impact	-0,23	high_impact	3,2	0,08	0,8	NA	NA	N	0,43	N	0,97	disease_causing	1	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10369	10369	A	G	MI.15622	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	311	104	Y	C	tAt/tGt	4,67	1	0	probably_damaging	1	neutral	0,13	neutral	0,42	deleterious	-8,59	deleterious	-8,7	high_impact	4,34	damaging	0,59	damaging	0,02	deleterious	3,69	23,3	0,08	0,35	disease	0,88	disease	0,88	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,87	low_impact	-3,43	medium_impact	-0,27	high_impact	2,87	0,06	0,8	NA	NA	P	0,56	P	1	polymorphism	1	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10369	10369	A	C	MI.15623	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	311	104	Y	S	tAt/tCt	4,67	1	0	probably_damaging	1	neutral	0,33	neutral	0,46	deleterious	-7,04	deleterious	-8,68	high_impact	4,34	damaging	0,59	damaging	0,06	deleterious	3,95	23,6	0,08	0,35	disease	0,7	disease	0,86	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	0,02	high_impact	2,87	0,08	0,8	NA	NA	P	0,55	P	0,98	polymorphism	1	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10369	10369	A	T	MI.15624	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	311	104	Y	F	tAt/tTt	4,67	1	0	probably_damaging	1	neutral	0,57	neutral	0,59	deleterious	-3,6	deleterious	-3,86	medium_impact	2,33	damaging	0,6	damaging	0,06	deleterious	3,6	23,2	0,14	0,4	neutral	0,31	disease	0,83	disease	0,56	disease	0,61	2	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,81	low_impact	-3,43	medium_impact	0,26	medium_impact	1,03	0,28	0,8	NA	NA	N	0,45	N	0,81	polymorphism	1	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10371	10371	G	A	MI.15625	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	313	105	E	K	Gag/Aag	-5,47	0	0	probably_damaging	1	neutral	0,24	neutral	0,69	neutral	-2,12	deleterious	-3,86	high_impact	4,26	damaging	0,39	damaging	0,28	deleterious	4,59	24,4	0,05	0,35	disease	0,63	disease	0,86	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-3,43	medium_impact	-0,09	high_impact	2,8	0,8	0,85	NA	NA	P	0,64	P	0,99	polymorphism	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10371	10371	G	C	MI.15626	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	313	105	E	Q	Gag/Cag	-5,47	0	0	probably_damaging	1	neutral	0,23	neutral	0,66	neutral	-2,66	deleterious	-2,9	high_impact	4,82	damaging	0,41	neutral	0,51	deleterious	3,47	23	0,13	0,4	disease	0,68	disease	0,75	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,84	low_impact	-3,43	medium_impact	-0,1	high_impact	3,31	0,71	0,85	NA	NA	P	0,73	P	0,9	polymorphism	1	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10372	10372	A	C	MI.15627	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	314	105	E	A	gAg/gCg	7,44	1	0	probably_damaging	1	neutral	0,37	neutral	0,76	neutral	-1,36	deleterious	-5,79	medium_impact	2,66	damaging	0,46	neutral	0,5	deleterious	3,8	23,4	0,05	0,35	disease	0,66	disease	0,74	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,85	low_impact	-3,43	medium_impact	0,06	medium_impact	1,33	0,39	0,8	NA	NA	P	0,67	P	0,76	polymorphism	1	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10372	10372	A	G	MI.15628	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	314	105	E	G	gAg/gGg	7,44	1	0	probably_damaging	1	neutral	0,34	neutral	0,62	deleterious	-3,63	deleterious	-6,76	high_impact	4,82	damaging	0,37	neutral	0,53	deleterious	4,43	24,2	0,03	0,35	disease	0,68	disease	0,76	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-3,43	medium_impact	0,03	high_impact	3,31	0,28	0,8	NA	NA	P	0,79	P	0,61	polymorphism	1	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10372	10372	A	T	MI.15629	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	314	105	E	V	gAg/gTg	7,44	1	0	probably_damaging	1	neutral	0,39	neutral	0,66	neutral	-2,54	deleterious	-6,76	medium_impact	3,1	damaging	0,36	neutral	0,36	deleterious	4,31	24	0,03	0,35	disease	0,8	disease	0,86	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,89	low_impact	-3,43	medium_impact	0,08	medium_impact	1,73	0,26	0,8	NA	NA	P	0,78	P	0,84	polymorphism	1	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8421	8421	C	A	MI.1563	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	56	19	T	K	aCa/aAa	-0,8	0	0	probably_damaging	0,99	neutral	0,05	neutral	1,75	deleterious	-4,03	deleterious	-4,96	high_impact	3,56	neutral	1	neutral	0,37	deleterious	4,16	23,8	0,23790843	0,85	disease	0,76	neutral	0,42	disease	0,75	neutral	0,3	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,83	low_impact	-2,65	medium_impact	-0,43	medium_impact	1,95	0,71	0,85	NA	NA	N	0,56	P	0,68	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10373	10373	G	T	MI.15630	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	315	105	E	D	gaG/gaT	8,59	1	0,03	probably_damaging	1	neutral	0,15	neutral	0,66	neutral	-2,68	deleterious	-2,9	high_impact	4,26	damaging	0,53	neutral	0,42	deleterious	3,96	23,6	0,19	0,45	neutral	0,5	disease	0,75	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-3,43	medium_impact	-0,23	high_impact	2,8	0,71	0,85	NA	NA	P	0,7	P	0,86	polymorphism	0,99	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10373	10373	G	C	MI.15631	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	315	105	E	D	gaG/gaC	8,59	1	0,03	probably_damaging	1	neutral	0,15	neutral	0,66	neutral	-2,68	deleterious	-2,9	high_impact	4,26	damaging	0,53	neutral	0,42	deleterious	3,78	23,4	0,19	0,45	neutral	0,5	disease	0,75	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-3,43	medium_impact	-0,23	high_impact	2,8	0,71	0,85	NA	NA	P	0,69	P	0,86	polymorphism	0,99	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10374	10374	T	C	MI.15632	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	316	106	W	R	Tga/Cga	0,52	0,99	0	probably_damaging	1	neutral	0,34	neutral	0,72	deleterious	-4,41	deleterious	-13,48	high_impact	4,48	neutral	0,62	damaging	0,03	deleterious	3,7	23,3	0,03	0,35	disease	0,86	disease	0,89	disease	0,79	disease	0,83	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,9	low_impact	-3,43	medium_impact	0,03	high_impact	3	0,06	0,8	NA	NA	P	0,59	P	0,97	polymorphism	1	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10374	10374	T	G	MI.15633	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	316	106	W	G	Tga/Gga	0,52	0,99	0	probably_damaging	1	neutral	0,34	neutral	0,72	deleterious	-4,82	deleterious	-12,54	high_impact	4,83	damaging	0,54	damaging	0,04	deleterious	3,99	23,6	0,04	0,35	disease	0,82	disease	0,83	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	0,03	high_impact	3,32	0,09	0,8	NA	NA	P	0,54	P	0,97	polymorphism	1	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10375	10375	G	T	MI.15634	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	317	106	W	L	tGa/tTa	5,83	1	0	probably_damaging	1	neutral	0,66	neutral	0,88	neutral	-2,33	deleterious	-12,54	medium_impact	3,08	damaging	0,55	damaging	0,02	deleterious	4,38	24,1	0,06	0,35	disease	0,74	disease	0,86	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,87	low_impact	-3,43	medium_impact	0,35	medium_impact	1,72	0,07	0,8	NA	NA	N	0,49	N	0,97	polymorphism	1	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10375	10375	G	C	MI.15635	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	317	106	W	S	tGa/tCa	5,83	1	0	probably_damaging	1	neutral	0,4	neutral	0,75	deleterious	-3,74	deleterious	-13,47	high_impact	4,48	damaging	0,55	damaging	0,04	deleterious	4,1	23,7	0,04	0,35	disease	0,86	disease	0,88	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,89	low_impact	-3,43	medium_impact	0,09	high_impact	3	0,07	0,8	NA	NA	P	0,6	P	0,95	disease_causing	1	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10376	10376	A	T	MI.15636	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	318	106	W	C	tgA/tgT	9,29	1	0	probably_damaging	1	neutral	0,17	neutral	0,71	deleterious	-5,39	deleterious	-12,55	high_impact	4,48	damaging	0,54	damaging	0,02	deleterious	4,21	23,9	0,03	0,35	disease	0,93	disease	0,87	disease	0,77	disease	0,84	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,43	medium_impact	-0,19	high_impact	3	0,12	0,8	NA	NA	P	0,6	P	0,98	polymorphism	1	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10376	10376	A	C	MI.15637	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	318	106	W	C	tgA/tgC	9,29	1	0	probably_damaging	1	neutral	0,17	neutral	0,71	deleterious	-5,39	deleterious	-12,55	high_impact	4,48	damaging	0,54	damaging	0,02	deleterious	4,09	23,7	0,03	0,35	disease	0,93	disease	0,87	disease	0,77	disease	0,84	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,43	medium_impact	-0,19	high_impact	3	0,12	0,8	NA	NA	P	0,59	P	0,98	polymorphism	1	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10377	10377	C	G	MI.15638	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	319	107	L	V	Cta/Gta	3,29	0,99	0	benign	0,12	neutral	0,52	neutral	0,99	neutral	-0,11	neutral	-0,41	low_impact	1,08	neutral	0,81	neutral	0,98	deleterious	0,26	5,3	0,27	0,45	neutral	0,22	neutral	0,12	neutral	0,13	neutral	0,3	4	neutral	0,39	deleterious	0,7	neutral	-6	neutral	0,1	medium_impact	0,06	medium_impact	0,21	medium_impact	-0,12	0,26	0,8	NA	NA	P	0,53	P	0,29	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10377	10377	C	A	MI.15639	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	319	107	L	M	Cta/Ata	3,29	0,99	0	possibly_damaging	0,7	neutral	0,25	neutral	0,95	neutral	-1,38	neutral	0,07	neutral_impact	0,56	neutral	0,8	neutral	0,96	deleterious	1,85	15,3	0,22	0,45	neutral	0,39	neutral	0,1	neutral	0,14	neutral	0,33	3	neutral	0,8	neutral	0,28	neutral	-3	deleterious	0,46	low_impact	-1,05	medium_impact	-0,08	medium_impact	-0,6	0,51	0,8	NA	NA	P	0,59	P	0,46	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8423	8423	C	G	MI.1564	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	58	20	L	V	Cta/Gta	-12,6	0	0	probably_damaging	0,97	neutral	0,09	neutral	1,22	deleterious	-8,3	deleterious	-2,99	high_impact	3,8	neutral	0,98	damaging	0,1	deleterious	3,25	22,8	0,41111942	0,85	disease	0,55	neutral	0,15	disease	0,71	neutral	0,22	6	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,74	low_impact	-2,19	medium_impact	-0,28	high_impact	2,16	0,7	0,85	NA	NA	N	0,46	N	0,46	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10378	10378	T	C	MI.15640	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	320	107	L	P	cTa/cCa	-7,55	0	0	benign	0,29	neutral	0,22	neutral	0,92	neutral	-1,24	neutral	-2,44	medium_impact	2,71	neutral	0,62	neutral	0,37	deleterious	2,27	17,96	0,04	0,35	neutral	0,49	disease	0,69	neutral	0,48	neutral	0,49	0	neutral	0,74	neutral	0,47	neutral	-3	neutral	0,33	medium_impact	-0,37	medium_impact	-0,12	medium_impact	1,38	0,08	0,8	NA	NA	N	0,33	N	0,6	polymorphism	1	0,62	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10378	10378	T	G	MI.15641	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	320	107	L	R	cTa/cGa	-7,55	0	0	benign	0,23	neutral	0,38	neutral	1	neutral	1,87	neutral	-2,05	neutral_impact	0,5	neutral	0,74	neutral	0,44	neutral	1,42	12,91	0,08	0,35	neutral	0,34	disease	0,55	neutral	0,39	neutral	0,5	0	neutral	0,54	deleterious	0,58	neutral	-6	neutral	0,26	medium_impact	-0,24	medium_impact	0,07	medium_impact	-0,65	0,15	0,8	NA	NA	N	0,34	N	0,46	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10378	10378	T	A	MI.15642	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	320	107	L	Q	cTa/cAa	-7,55	0	0	benign	0,29	neutral	0,36	neutral	0,98	neutral	0,38	neutral	-1,68	low_impact	1,52	neutral	0,76	neutral	0,51	neutral	1,53	13,49	0,1	0,4	neutral	0,34	neutral	0,35	neutral	0,32	neutral	0,46	1	neutral	0,57	deleterious	0,54	neutral	-6	neutral	0,22	medium_impact	-0,37	medium_impact	0,05	medium_impact	0,29	0,16	0,8	NA	NA	N	0,38	N	0,46	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10380	10380	C	G	MI.15643	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	322	108	Q	E	Caa/Gaa	-15,39	0	0	probably_damaging	1	neutral	0,35	neutral	1,08	neutral	0,43	neutral	-2,06	low_impact	0,9	neutral	0,76	neutral	0,75	deleterious	3,16	22,6	0,5	0,6	neutral	0,2	neutral	0,5	neutral	0,35	neutral	0,42	2	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,73	low_impact	-3,43	medium_impact	0,04	medium_impact	-0,28	0,62	0,8	NA	NA	N	0,36	N	0,37	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10380	10380	C	A	MI.15644	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	322	108	Q	K	Caa/Aaa	-15,39	0	0	probably_damaging	1	neutral	0,28	neutral	1,12	neutral	2,12	deleterious	-2,85	low_impact	1,29	neutral	0,73	neutral	0,44	deleterious	4,04	23,7	0,45	0,55	neutral	0,32	disease	0,64	neutral	0,46	neutral	0,45	1	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,77	low_impact	-3,43	medium_impact	-0,04	medium_impact	0,07	0,46	0,8	NA	NA	N	0,39	N	0,88	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10381	10381	A	C	MI.15645	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	323	108	Q	P	cAa/cCa	3,52	0,99	0	probably_damaging	1	neutral	0,19	neutral	0,93	neutral	-1,88	deleterious	-4,85	high_impact	3,96	neutral	0,62	neutral	0,34	deleterious	3,24	22,8	0,08	0,35	disease	0,63	disease	0,79	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,43	medium_impact	-0,16	high_impact	2,52	0,4	0,8	NA	NA	P	0,6	P	0,89	polymorphism	1	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10381	10381	A	T	MI.15646	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	323	108	Q	L	cAa/cTa	3,52	0,99	0	probably_damaging	1	neutral	0,68	neutral	0,97	neutral	-1,13	deleterious	-5,86	medium_impact	2,54	neutral	0,67	neutral	0,41	deleterious	3,69	23,3	0,16	0,45	disease	0,58	disease	0,78	disease	0,51	disease	0,62	2	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	0,37	medium_impact	1,22	0,32	0,8	NA	NA	N	0,41	N	0,9	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10381	10381	A	G	MI.15647	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	323	108	Q	R	cAa/cGa	3,52	0,99	0	probably_damaging	1	neutral	0,33	neutral	0,98	neutral	0,73	deleterious	-3	medium_impact	2,12	neutral	0,73	neutral	0,35	deleterious	3,33	22,9	0,56	0,6	neutral	0,39	disease	0,69	neutral	0,5	neutral	0,47	1	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,8	low_impact	-3,43	medium_impact	0,02	medium_impact	0,84	0,28	0,8	NA	NA	N	0,48	N	0,74	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10382	10382	A	T	MI.15648	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	324	108	Q	H	caA/caT	8,59	1	0	probably_damaging	1	neutral	0,51	neutral	0,94	neutral	-1,27	deleterious	-3,71	medium_impact	3,26	neutral	0,73	neutral	0,55	deleterious	3,61	23,2	0,33	0,5	disease	0,59	disease	0,59	neutral	0,5	neutral	0,46	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,79	low_impact	-3,43	medium_impact	0,2	medium_impact	1,88	0,4	0,8	NA	NA	P	0,62	P	0,85	polymorphism	1	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10382	10382	A	C	MI.15649	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	324	108	Q	H	caA/caC	8,59	1	0	probably_damaging	1	neutral	0,51	neutral	0,94	neutral	-1,27	deleterious	-3,71	medium_impact	3,26	neutral	0,73	neutral	0,55	deleterious	3,48	23,1	0,33	0,5	disease	0,59	disease	0,59	neutral	0,5	neutral	0,46	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,79	low_impact	-3,43	medium_impact	0,2	medium_impact	1,88	0,4	0,8	NA	NA	P	0,62	P	0,85	polymorphism	1	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8423	8423	C	A	MI.1565	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	58	20	L	M	Cta/Ata	-12,6	0	0	probably_damaging	1	neutral	0,06	neutral	1,19	deleterious	-8,54	neutral	-2	medium_impact	3,25	neutral	0,98	damaging	0,09	deleterious	3,6	23,2	0,34020157	0,85	disease	0,63	neutral	0,18	disease	0,68	neutral	0,24	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	-0,38	medium_impact	1,69	0,61	0,85	NA	NA	N	0,44	N	0,61	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10383	10383	A	G	MI.15650	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	325	109	K	E	Aaa/Gaa	3,98	1	0	probably_damaging	1	neutral	0,33	neutral	0,97	neutral	-0,87	deleterious	-2,81	medium_impact	2,68	neutral	0,86	neutral	0,72	deleterious	2,47	19,25	0,23	0,45	neutral	0,34	disease	0,66	disease	0,61	disease	0,64	3	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,77	low_impact	-3,43	medium_impact	0,02	medium_impact	1,35	0,53	0,8	NA	NA	P	0,54	P	0,86	polymorphism	1	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10383	10383	A	C	MI.15651	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	325	109	K	Q	Aaa/Caa	3,98	1	0	probably_damaging	1	neutral	0,37	neutral	0,92	neutral	-1,62	deleterious	-2,98	medium_impact	2,52	neutral	0,79	damaging	0,13	deleterious	2,19	17,42	0,34	0,5	neutral	0,4	neutral	0,39	disease	0,58	neutral	0,46	1	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,72	low_impact	-3,43	medium_impact	0,06	medium_impact	1,2	0,42	0,8	NA	NA	N	0,49	N	0,86	polymorphism	1	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10384	10384	A	C	MI.15652	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	326	109	K	T	aAa/aCa	3,29	1	0	probably_damaging	1	neutral	0,39	neutral	0,91	neutral	-1,99	deleterious	-4,67	medium_impact	3,15	neutral	0,76	damaging	0,14	deleterious	2,4	18,82	0,16	0,45	neutral	0,43	neutral	0,4	disease	0,6	neutral	0,46	1	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,73	low_impact	-3,43	medium_impact	0,08	medium_impact	1,78	0,33	0,8	NA	NA	N	0,48	N	0,81	polymorphism	1	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10384	10384	A	T	MI.15653	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	326	109	K	M	aAa/aTa	3,29	1	0	probably_damaging	1	neutral	0,22	neutral	0,87	deleterious	-3,75	deleterious	-4,87	medium_impact	3,49	neutral	0,78	damaging	0,13	deleterious	3,83	23,4	0,09	0,35	disease	0,71	neutral	0,48	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,78	low_impact	-3,43	medium_impact	-0,12	high_impact	2,09	0,35	0,8	NA	NA	P	0,54	P	0,54	polymorphism	1	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10385	10385	A	T	MI.15654	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	327	109	K	N	aaA/aaT	5,83	1	0	probably_damaging	1	neutral	0,36	neutral	0,94	neutral	-1,69	deleterious	-3,61	low_impact	1,31	neutral	0,75	damaging	0,13	deleterious	2,35	18,47	0,38	0,5	neutral	0,43	disease	0,6	neutral	0,49	neutral	0,48	0	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,77	low_impact	-3,43	medium_impact	0,05	medium_impact	0,09	0,37	0,8	NA	NA	N	0,53	P	0,71	polymorphism	1	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10385	10385	A	C	MI.15655	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	327	109	K	N	aaA/aaC	5,83	1	0	probably_damaging	1	neutral	0,36	neutral	0,94	neutral	-1,69	deleterious	-3,61	low_impact	1,31	neutral	0,75	damaging	0,13	deleterious	2,17	17,31	0,38	0,5	neutral	0,43	disease	0,6	neutral	0,49	neutral	0,48	0	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,77	low_impact	-3,43	medium_impact	0,05	medium_impact	0,09	0,37	0,8	NA	NA	N	0,53	P	0,71	polymorphism	1	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10386	10386	G	C	MI.15656	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	328	110	G	R	Gga/Cga	-0,4	0,32	0	probably_damaging	1	neutral	0,39	neutral	0,98	neutral	-0,6	deleterious	-7,28	medium_impact	3,42	neutral	0,66	damaging	0,04	deleterious	4,29	24	0,12	0,4	neutral	0,49	disease	0,67	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,82	low_impact	-3,43	medium_impact	0,08	high_impact	2,03	0,5	0,8	NA	NA	N	0,28	N	1	polymorphism	1	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10386	10386	G	T	MI.15657	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	328	110	G	W	Gga/Tga	-0,4	0,32	0	probably_damaging	1	neutral	0,29	neutral	0,94	neutral	-2,88	deleterious	-7,36	high_impact	3,76	neutral	0,67	damaging	0,04	deleterious	4,77	24,7	0,13	0,4	disease	0,85	disease	0,76	disease	0,66	disease	0,76	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,43	medium_impact	-0,03	high_impact	2,34	0,07	0,8	NA	NA	N	0,33	N	1	polymorphism	1	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10387	10387	G	T	MI.15658	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	329	110	G	V	gGa/gTa	6,06	1	0	probably_damaging	1	neutral	0,56	neutral	1,1	neutral	1,34	deleterious	-8,22	medium_impact	2,19	neutral	0,61	damaging	0,04	deleterious	4,12	23,8	0,13	0,4	neutral	0,38	disease	0,62	disease	0,57	disease	0,64	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,77	low_impact	-3,43	medium_impact	0,25	medium_impact	0,9	0,04	0,8	NA	NA	N	0,41	N	0,98	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10387	10387	G	A	MI.15659	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	329	110	G	E	gGa/gAa	6,06	1	0	probably_damaging	1	neutral	0,42	neutral	0,99	neutral	-0,2	deleterious	-7,25	high_impact	3,76	neutral	0,67	damaging	0,06	deleterious	4,29	24	0,14	0,4	neutral	0,43	disease	0,66	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,79	low_impact	-3,43	medium_impact	0,11	high_impact	2,34	0,15	0,8	NA	NA	P	0,55	P	1	polymorphism	1	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8424	8424	T	A	MI.1566	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	59	20	L	Q	cTa/cAa	-0,8	0	0	probably_damaging	1	deleterious	0	neutral	1,17	deleterious	-11,19	deleterious	-5,99	high_impact	3,8	neutral	0,97	damaging	0,06	deleterious	4,08	23,7	0,20000037	0,85	disease	0,87	neutral	0,42	disease	0,7	neutral	0,31	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,6	low_impact	-1,4	high_impact	2,16	0,62	0,85	NA	NA	N	0,48	N	0,91	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10387	10387	G	C	MI.15660	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	329	110	G	A	gGa/gCa	6,06	1	0	probably_damaging	1	neutral	0,59	neutral	1,17	neutral	1,89	deleterious	-5,39	low_impact	1,27	neutral	0,69	damaging	0,16	deleterious	3,42	23	0,27	0,45	neutral	0,28	neutral	0,3	neutral	0,31	neutral	0,39	2	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,72	low_impact	-3,43	medium_impact	0,28	medium_impact	0,06	0,33	0,8	NA	NA	N	0,48	N	0,81	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10389	10389	T	G	MI.15661	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	331	111	L	V	Tta/Gta	-8,7	0	0	probably_damaging	1	neutral	0,58	neutral	0,1	deleterious	-3,97	deleterious	-2,78	high_impact	3,78	damaging	0,42	damaging	0,02	deleterious	3,78	23,4	0,13	0,4	neutral	0,4	neutral	0,21	disease	0,71	neutral	0,43	1	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,72	low_impact	-3,43	medium_impact	0,27	high_impact	2,36	0,42	0,8	NA	NA	N	0,46	N	0,89	polymorphism	1	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10389	10389	T	A	MI.15662	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	331	111	L	M	Tta/Ata	-8,7	0	0	probably_damaging	1	neutral	0,25	neutral	0,11	deleterious	-4,81	neutral	-1,86	high_impact	4,01	damaging	0,49	damaging	0,03	deleterious	3,96	23,6	0,13	0,4	disease	0,53	neutral	0,21	disease	0,62	neutral	0,4	2	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,72	low_impact	-3,43	medium_impact	-0,08	high_impact	2,57	0,43	0,8	NA	NA	N	0,39	N	0,91	polymorphism	1	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10390	10390	T	C	MI.15663	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	332	111	L	S	tTa/tCa	-0,4	0	0	probably_damaging	1	neutral	0,58	neutral	-0,01	deleterious	-7,17	deleterious	-5,56	high_impact	4,27	damaging	0,43	damaging	0,03	deleterious	4,1	23,7	0,03	0,35	disease	0,69	neutral	0,39	disease	0,7	disease	0,59	2	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,8	low_impact	-3,43	medium_impact	0,27	high_impact	2,81	0,2	0,8	NA	NA	N	0,48	N	0,97	polymorphism	1	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10390	10390	T	G	MI.15664	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	332	111	L	W	tTa/tGa	-0,4	0	0	probably_damaging	1	neutral	0,22	neutral	-0,03	deleterious	-8,47	deleterious	-5,58	high_impact	4,82	damaging	0,47	damaging	0,01	deleterious	4,12	23,8	0,05	0,35	disease	0,89	neutral	0,41	disease	0,73	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,81	low_impact	-3,43	medium_impact	-0,12	high_impact	3,31	0,23	0,8	NA	NA	P	0,56	P	0,98	polymorphism	1	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10391	10391	A	C	MI.15665	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	333	111	L	F	ttA/ttC	7,44	0,99	0	probably_damaging	1	neutral	0,72	neutral	0,05	deleterious	-4,49	deleterious	-3,71	medium_impact	3,29	damaging	0,45	damaging	0,01	deleterious	3,82	23,4	0,12	0,4	disease	0,56	neutral	0,29	disease	0,7	disease	0,55	1	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,76	low_impact	-3,43	medium_impact	0,42	medium_impact	1,91	0,49	0,8	NA	NA	P	0,6	P	0,99	polymorphism	1	0,62	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10391	10391	A	T	MI.15666	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	333	111	L	F	ttA/ttT	7,44	0,99	0	probably_damaging	1	neutral	0,72	neutral	0,05	deleterious	-4,49	deleterious	-3,71	medium_impact	3,29	damaging	0,45	damaging	0,01	deleterious	3,9	23,5	0,12	0,4	disease	0,56	neutral	0,29	disease	0,7	disease	0,55	1	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,76	low_impact	-3,43	medium_impact	0,42	medium_impact	1,91	0,49	0,8	NA	NA	P	0,6	P	0,99	polymorphism	1	0,62	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10392	10392	G	C	MI.15667	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	334	112	D	H	Gac/Cac	-0,17	0,89	0	probably_damaging	0,96	neutral	0,55	neutral	0,87	neutral	-2,27	neutral	-2,49	medium_impact	2,56	neutral	0,71	neutral	0,5	deleterious	3,82	23,4	0,27	0,45	disease	0,53	neutral	0,16	disease	0,51	neutral	0,3	4	neutral	0,96	neutral	0,3	deleterious	1	deleterious	0,71	low_impact	-1,96	medium_impact	0,24	medium_impact	1,24	0,61	0,8	NA	NA	N	0,32	N	0,63	polymorphism	1	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10392	10392	G	A	MI.15668	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	334	112	D	N	Gac/Aac	-0,17	0,89	0	benign	0,08	neutral	0,38	neutral	0,92	neutral	-0,59	neutral	-2,23	low_impact	1,02	neutral	0,72	neutral	0,56	deleterious	4,1	23,7	0,84	0,85	neutral	0,19	neutral	0,27	neutral	0,32	neutral	0,39	2	neutral	0,57	deleterious	0,65	neutral	-6	neutral	0,18	medium_impact	0,24	medium_impact	0,07	medium_impact	-0,17	0,7	0,85	NA	NA	N	0,42	N	0,47	polymorphism	0,99	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10392	10392	G	T	MI.15669	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	334	112	D	Y	Gac/Tac	-0,17	0,89	0	probably_damaging	0,98	neutral	1	neutral	0,85	deleterious	-3,14	deleterious	-4,35	medium_impact	2,15	neutral	0,71	neutral	0,56	deleterious	4,14	23,8	0,11	0,4	disease	0,7	neutral	0,38	disease	0,51	disease	0,62	2	neutral	0,97	deleterious	0,51	deleterious	1	deleterious	0,79	low_impact	-2,24	high_impact	1,85	medium_impact	0,86	0,09	0,8	NA	NA	N	0,27	N	0,93	polymorphism	1	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8424	8424	T	G	MI.1567	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	59	20	L	R	cTa/cGa	-0,8	0	0	probably_damaging	1	deleterious	0	neutral	1,17	deleterious	-11,06	deleterious	-5,99	high_impact	3,8	neutral	0,97	damaging	0,04	deleterious	3,99	23,6	0,18482793	0,85	disease	0,86	disease	0,55	disease	0,78	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,16	0,43	0,85	NA	NA	N	0,5	N	0,96	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10393	10393	A	C	MI.15670	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	335	112	D	A	gAc/gCc	7,44	1	0	possibly_damaging	0,64	neutral	0,63	neutral	0,94	neutral	-0,81	deleterious	-3,41	medium_impact	2,7	neutral	0,71	neutral	0,67	deleterious	3,45	23	0,31	0,45	neutral	0,37	neutral	0,24	neutral	0,47	neutral	0,41	2	neutral	0,57	deleterious	0,5	NA	0	deleterious	0,54	medium_impact	-0,94	medium_impact	0,32	medium_impact	1,37	0,38	0,8	NA	NA	P	0,6	P	0,71	polymorphism	0,89	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10393	10393	A	T	MI.15671	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	335	112	D	V	gAc/gTc	7,44	1	0	probably_damaging	0,9	neutral	0,55	neutral	0,87	neutral	-2,14	deleterious	-4,35	medium_impact	2,7	neutral	0,72	neutral	0,62	deleterious	3,8	23,4	0,13	0,4	disease	0,6	neutral	0,3	neutral	0,47	disease	0,57	1	neutral	0,89	neutral	0,33	deleterious	1	deleterious	0,7	low_impact	-1,58	medium_impact	0,24	medium_impact	1,37	0,12	0,8	NA	NA	P	0,6	P	0,86	polymorphism	0,78	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10393	10393	A	G	MI.15672	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	335	112	D	G	gAc/gGc	7,44	1	0	possibly_damaging	0,64	neutral	0,4	neutral	0,87	neutral	-1,93	deleterious	-4,08	medium_impact	2,9	neutral	0,78	neutral	0,53	deleterious	3,87	23,5	0,28	0,45	neutral	0,4	neutral	0,26	neutral	0,47	neutral	0,41	2	neutral	0,67	neutral	0,38	NA	0	deleterious	0,57	medium_impact	-0,94	medium_impact	0,09	medium_impact	1,55	0,33	0,8	NA	NA	P	0,66	P	0,81	polymorphism	0,96	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10394	10394	C	G	MI.15673	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	336	112	D	E	gaC/gaG	8,59	1	0	benign	0,05	neutral	0,45	neutral	1,06	neutral	0,71	neutral	1,88	neutral_impact	-0,94	neutral	0,83	neutral	0,93	neutral	-0,48	0,25	0,55	0,6	neutral	0,09	neutral	0,02	neutral	0,13	neutral	0,23	5	neutral	0,51	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	0,44	medium_impact	0,14	low_impact	-1,97	0,57	0,8	NA	NA	P	0,59	P	0,06	disease_causing	0,68	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10394	10394	C	A	MI.15674	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	336	112	D	E	gaC/gaA	8,59	1	0	benign	0,05	neutral	0,45	neutral	1,06	neutral	0,71	neutral	1,88	neutral_impact	-0,94	neutral	0,83	neutral	0,93	neutral	-0,27	0,79	0,55	0,6	neutral	0,09	neutral	0,02	neutral	0,13	neutral	0,23	5	neutral	0,51	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	0,44	medium_impact	0,14	low_impact	-1,97	0,57	0,8	NA	NA	P	0,59	P	0,06	disease_causing	0,68	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10395	10395	T	G	MI.15675	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	337	113	W	G	Tga/Gga	0,06	0,92	0	probably_damaging	1	neutral	0,57	neutral	0,12	deleterious	-7,74	deleterious	-12,13	high_impact	4,72	damaging	0,54	damaging	0,04	deleterious	4,16	23,8	0,05	0,35	disease	0,82	neutral	0,46	disease	0,72	disease	0,65	3	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,82	low_impact	-3,43	medium_impact	0,26	high_impact	3,22	0,11	0,8	NA	NA	P	0,49	N	0,98	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10395	10395	T	C	MI.15676	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	337	113	W	R	Tga/Cga	0,06	0,92	0	probably_damaging	1	neutral	0,69	neutral	0,14	deleterious	-7,7	deleterious	-13,06	high_impact	4,17	neutral	0,62	damaging	0,03	deleterious	3,87	23,5	0,04	0,35	disease	0,86	disease	0,58	disease	0,74	disease	0,76	5	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,85	low_impact	-3,43	medium_impact	0,38	high_impact	2,72	0,12	0,8	NA	NA	N	0,47	N	0,97	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10396	10396	G	C	MI.15677	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	338	113	W	S	tGa/tCa	5,83	1	0	probably_damaging	1	neutral	0,89	neutral	0,14	deleterious	-7,3	deleterious	-13,06	high_impact	4,72	damaging	0,55	damaging	0,04	deleterious	4,24	23,9	0,05	0,35	disease	0,86	disease	0,6	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,85	low_impact	-3,43	medium_impact	0,69	high_impact	3,22	0,13	0,8	NA	NA	P	0,55	P	0,96	disease_causing	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10396	10396	G	T	MI.15678	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	338	113	W	L	tGa/tTa	5,83	1	0	probably_damaging	1	neutral	0,81	neutral	0,22	deleterious	-5,64	deleterious	-12,13	high_impact	3,92	damaging	0,55	damaging	0,02	deleterious	4,42	24,2	0,06	0,35	disease	0,74	neutral	0,46	disease	0,71	disease	0,6	2	deleterious	1	neutral	0,41	deleterious	2	deleterious	0,81	low_impact	-3,43	medium_impact	0,54	high_impact	2,49	0,09	0,8	NA	NA	P	0,54	P	0,97	polymorphism	1	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10397	10397	A	C	MI.15679	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	339	113	W	C	tgA/tgC	7,21	1	0,08	probably_damaging	1	neutral	0,19	neutral	0,12	deleterious	-8,89	deleterious	-12,13	high_impact	4,72	damaging	0,54	damaging	0,02	deleterious	4,25	23,9	0,05	0,35	disease	0,93	disease	0,57	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,43	medium_impact	-0,16	high_impact	3,22	0,11	0,8	NA	NA	P	0,54	P	0,98	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8424	8424	T	C	MI.1568	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	59	20	L	P	cTa/cCa	-0,8	0	0	probably_damaging	1	deleterious	0	neutral	1,16	deleterious	-11,31	deleterious	-6,99	high_impact	3,8	neutral	0,97	damaging	0,04	deleterious	3,83	23,4	0,25207871	0,85	disease	0,89	neutral	0,46	disease	0,78	neutral	0,42	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,6	low_impact	-1,4	high_impact	2,16	0,58	0,85	NA	NA	N	0,49	N	0,97	polymorphism	0,85	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10397	10397	A	T	MI.15680	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	339	113	W	C	tgA/tgT	7,21	1	0,08	probably_damaging	1	neutral	0,19	neutral	0,12	deleterious	-8,89	deleterious	-12,13	high_impact	4,72	damaging	0,54	damaging	0,02	deleterious	4,37	24,1	0,05	0,35	disease	0,93	disease	0,57	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,43	medium_impact	-0,16	high_impact	3,22	0,11	0,8	NA	NA	P	0,53	P	0,98	polymorphism	1	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10398	10398	A	G	MI.15681	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	340	114	T	A	Acc/Gcc	-0,17	0	0,83	benign	0	neutral	0,83	neutral	2,08	neutral	0,42	neutral	-1,39	neutral_impact	-0,24	neutral	0,95	neutral	0,89	neutral	-0,99	0,02	0,36	0,5	neutral	0,09	neutral	0,01	neutral	0,28	neutral	0,17	7	neutral	0,17	deleterious	0,92	neutral	-6	neutral	0,04	medium_impact	1,99	medium_impact	0,57	low_impact	-1,33	0,37	0,8	NA	NA	N	0,44	N	0	polymorphism	1	0,18	rs2853826	other	Parkinson_disease,_resistance_to	RCV000010359.3	MedGen	thyroid tumor	.	.	.	A10398G	PD protective factor/longevity/altered cell pH/metabolic syndrome/breast cancer risk	+	-	Reported,haplogroup IJK marker	27
chrM	10398	10398	A	T	MI.15682	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	340	114	T	S	Acc/Tcc	-0,17	0	0,83	benign	0,02	neutral	0,77	neutral	2	neutral	0,06	neutral	-1,4	low_impact	0,97	neutral	0,84	neutral	0,81	deleterious	0,51	7,47	0,5	0,6	neutral	0,13	neutral	0,07	neutral	0,31	neutral	0,29	4	neutral	0,19	deleterious	0,88	neutral	-6	neutral	0,09	medium_impact	0,81	medium_impact	0,48	medium_impact	-0,22	0,52	0,8	NA	NA	N	0,33	N	0,36	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10398	10398	A	C	MI.15683	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	340	114	T	P	Acc/Ccc	-0,17	0	0,83	benign	0,08	neutral	0,3	neutral	1,91	neutral	-1,94	deleterious	-3,18	medium_impact	2,13	neutral	0,62	neutral	0,31	deleterious	1,82	15,11	0,2	0,45	neutral	0,44	neutral	0,38	neutral	0,5	neutral	0,44	1	neutral	0,66	deleterious	0,61	neutral	-3	neutral	0,2	medium_impact	0,24	medium_impact	-0,01	medium_impact	0,84	0,37	0,8	NA	NA	N	0,41	N	0,68	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10399	10399	C	G	MI.15684	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	341	114	T	S	aCc/aGc	-0,17	0	0	benign	0,02	neutral	0,77	neutral	2	neutral	0,06	neutral	-1,4	low_impact	0,97	neutral	0,84	neutral	0,81	deleterious	0,57	7,97	0,5	0,6	neutral	0,13	neutral	0,07	neutral	0,31	neutral	0,29	4	neutral	0,19	deleterious	0,88	neutral	-6	neutral	0,09	medium_impact	0,81	medium_impact	0,48	medium_impact	-0,22	0,52	0,8	NA	NA	N	0,34	N	0,36	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10399	10399	C	A	MI.15685	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	341	114	T	N	aCc/aAc	-0,17	0	0	benign	0	neutral	0,55	neutral	1,94	neutral	-0,77	neutral	-2,47	low_impact	0,98	neutral	0,8	neutral	0,78	neutral	0,89	10,05	0,49	0,55	neutral	0,38	neutral	0,28	neutral	0,45	neutral	0,42	2	neutral	0,45	deleterious	0,78	neutral	-6	neutral	0,12	medium_impact	1,99	medium_impact	0,24	medium_impact	-0,21	0,43	0,8	NA	NA	N	0,3	N	0,59	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10399	10399	C	T	MI.15686	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	341	114	T	I	aCc/aTc	-0,17	0	0	benign	0	neutral	0,29	neutral	1,98	neutral	0,05	deleterious	-3,08	low_impact	1,17	neutral	0,82	neutral	0,8	deleterious	2,01	16,29	0,28	0,45	neutral	0,43	neutral	0,16	neutral	0,46	neutral	0,34	3	neutral	0,71	deleterious	0,65	neutral	-6	neutral	0,14	medium_impact	1,99	medium_impact	-0,03	medium_impact	-0,04	0,36	0,8	NA	NA	N	0,38	N	0,54	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10401	10401	G	C	MI.15687	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	343	115	E	Q	Gaa/Caa	-7,09	0	0	probably_damaging	1	neutral	0,58	neutral	1,66	neutral	-1,29	deleterious	-2,54	medium_impact	2,44	damaging	0,57	damaging	0,17	deleterious	3,47	23	0,29	0,45	disease	0,55	neutral	0,19	neutral	0,45	neutral	0,38	2	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,91	low_impact	-3,43	medium_impact	0,27	medium_impact	1,13	0,6	0,8	NA	NA	N	0,28	N	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10401	10401	G	A	MI.15688	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	343	115	E	K	Gaa/Aaa	-7,09	0	0	probably_damaging	1	neutral	0,92	neutral	1,69	neutral	-0,72	deleterious	-3,31	low_impact	1,61	damaging	0,55	neutral	0,66	deleterious	4,52	24,3	0,24	0,45	neutral	0,49	neutral	0,26	neutral	0,35	neutral	0,36	3	deleterious	0,99	neutral	0,46	neutral	-2	deleterious	0,92	low_impact	-3,43	medium_impact	0,78	medium_impact	0,37	0,46	0,8	NA	NA	N	0,31	N	0,99	polymorphism	1	0,07	rs28719882	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10402	10402	A	T	MI.15689	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	344	115	E	V	gAa/gTa	1,44	0,98	0	probably_damaging	1	neutral	0,29	neutral	1,62	neutral	-1,58	deleterious	-6,2	medium_impact	2,87	damaging	0,5	damaging	0,09	deleterious	4,37	24,1	0,12	0,4	disease	0,69	neutral	0,31	disease	0,51	disease	0,57	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,92	low_impact	-3,43	medium_impact	-0,03	medium_impact	1,52	0,41	0,8	NA	NA	P	0,54	P	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8426	8426	T	A	MI.1569	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	61	21	F	I	Ttc/Atc	-2,19	0	0	probably_damaging	0,97	neutral	0,5	neutral	1,86	deleterious	-5,37	deleterious	-5,5	medium_impact	2,62	neutral	1	neutral	0,47	deleterious	4,23	23,9	0,25340804	0,85	disease	0,72	neutral	0,42	disease	0,65	neutral	0,28	5	neutral	0,97	neutral	0,27	deleterious	1	deleterious	0,78	low_impact	-2,19	medium_impact	0,29	medium_impact	1,15	0,51	0,85	NA	NA	N	0,48	N	0,8	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10402	10402	A	G	MI.15690	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	344	115	E	G	gAa/gGa	1,44	0,98	0	probably_damaging	1	neutral	0,38	neutral	1,64	neutral	-1,72	deleterious	-6,19	medium_impact	3,07	damaging	0,5	damaging	0,15	deleterious	4,39	24,1	0,2	0,45	disease	0,56	neutral	0,2	disease	0,51	neutral	0,41	2	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,91	low_impact	-3,43	medium_impact	0,07	medium_impact	1,71	0,35	0,8	NA	NA	P	0,58	P	0,6	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10402	10402	A	C	MI.15691	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	344	115	E	A	gAa/gCa	1,44	0,98	0	probably_damaging	1	neutral	0,76	neutral	1,67	neutral	-1,02	deleterious	-5,29	medium_impact	3,42	damaging	0,57	damaging	0,13	deleterious	3,79	23,4	0,23	0,45	disease	0,53	neutral	0,23	neutral	0,48	neutral	0,33	3	deleterious	0,99	neutral	0,38	deleterious	1	deleterious	0,91	low_impact	-3,43	medium_impact	0,47	high_impact	2,03	0,35	0,8	NA	NA	N	0,48	N	0,74	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10403	10403	A	C	MI.15692	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	345	115	E	D	gaA/gaC	5,6	1	0	probably_damaging	0,99	neutral	0,62	neutral	1,72	neutral	-0,78	deleterious	-2,65	medium_impact	2,52	neutral	0,62	damaging	0,13	deleterious	3,76	23,3	0,36	0,5	neutral	0,38	neutral	0,16	neutral	0,3	neutral	0,26	5	deleterious	0,99	neutral	0,32	deleterious	1	deleterious	0,9	low_impact	-2,52	medium_impact	0,31	medium_impact	1,2	0,51	0,8	NA	NA	P	0,56	P	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10403	10403	A	T	MI.15693	MT-ND3	I	ENSG00000198840	ENSP00000355206	ENST00000361227	NU3M_HUMAN	P03897	4537	YP_003024033.1	345	115	E	D	gaA/gaT	5,6	1	0	probably_damaging	0,99	neutral	0,62	neutral	1,72	neutral	-0,78	deleterious	-2,65	medium_impact	2,52	neutral	0,62	damaging	0,13	deleterious	3,89	23,5	0,36	0,5	neutral	0,38	neutral	0,16	neutral	0,3	neutral	0,26	5	deleterious	0,99	neutral	0,32	deleterious	1	deleterious	0,9	low_impact	-2,52	medium_impact	0,31	medium_impact	1,2	0,51	0,8	NA	NA	P	0,57	P	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10470	10470	A	C	MI.15694	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	1	1	M	L	Atg/Ctg	0,29	0,02	0	probably_damaging	0,97	deleterious	0	neutral	2,06	neutral	0,92	deleterious	-2,89	NA	NA	damaging	0,55	damaging	0,13	deleterious	2,91	21,9	0,52	0,6	neutral	0,44	neutral	0,42	disease	0,56	neutral	0,43	1	deleterious	1	neutral	0,02	deleterious	4	deleterious	0,73	NA	NA	NA	NA	NA	NA	0,55	0,8	53,06	11,94	N	0,36	N	0,88	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10471	10471	T	A	MI.15695	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	2	1	M	K	aTg/aAg	4,67	1	0	probably_damaging	0,99	deleterious	0	neutral	1,85	neutral	-1,35	deleterious	-5,57	NA	NA	damaging	0,57	damaging	0,13	deleterious	3,86	23,5	0,31	0,45	disease	0,62	disease	0,63	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	4	deleterious	0,84	NA	NA	NA	NA	NA	NA	0,38	0,8	53,06	11,94	P	0,52	P	0,93	NA	NA	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10473	10473	C	A	MI.15696	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	4	2	P	T	Ccc/Acc	3,52	1	0	benign	0,03	neutral	0,69	neutral	2,02	neutral	0,36	neutral	-1,61	neutral_impact	0,04	neutral	0,9	neutral	0,99	neutral	-1,27	0,01	0,55	0,6	neutral	0,12	neutral	0,05	neutral	0,12	neutral	0,23	5	neutral	0,26	deleterious	0,83	neutral	-6	neutral	0,07	medium_impact	0,58	medium_impact	0,4	low_impact	-1,1	0,61	0,8	29,59	16,37	N	0,51	P	0,03	polymorphism	0,91	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10473	10473	C	T	MI.15697	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	4	2	P	S	Ccc/Tcc	3,52	1	0	benign	0,04	neutral	0,75	neutral	2,05	neutral	0,54	neutral	-1,52	neutral_impact	0,16	neutral	0,93	neutral	1	neutral	-0,76	0,05	0,6	0,65	neutral	0,11	neutral	0,05	neutral	0,12	neutral	0,24	5	neutral	0,18	deleterious	0,86	neutral	-6	neutral	0,07	medium_impact	0,46	medium_impact	0,48	low_impact	-1	0,37	0,8	29,59	16,37	N	0,5	N	0,06	polymorphism	0,9	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10473	10473	C	G	MI.15698	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	4	2	P	A	Ccc/Gcc	3,52	1	0	benign	0,21	neutral	0,52	neutral	2,04	neutral	0,64	deleterious	-2,57	neutral_impact	0,26	neutral	0,9	neutral	0,87	neutral	-0,24	0,9	0,58	0,65	neutral	0,16	neutral	0,09	neutral	0,29	neutral	0,25	5	neutral	0,37	deleterious	0,66	neutral	-6	neutral	0,14	medium_impact	-0,28	medium_impact	0,23	medium_impact	-0,92	0,62	0,8	29,59	16,37	N	0,5	N	0,28	polymorphism	0,94	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10474	10474	C	G	MI.15699	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	5	2	P	R	cCc/cGc	-2,48	0	0	possibly_damaging	0,71	neutral	0,28	neutral	2	neutral	-0,7	deleterious	-3,73	low_impact	1,9	neutral	0,8	neutral	0,51	neutral	1,63	13,99	0,44	0,55	neutral	0,2	neutral	0,39	neutral	0,41	neutral	0,44	1	neutral	0,79	neutral	0,29	neutral	-3	deleterious	0,45	low_impact	-1,16	medium_impact	-0,02	medium_impact	0,46	0,42	0,8	29,59	16,37	N	0,37	N	0,59	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8599	8599	C	A	MI.157	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	73	25	L	M	Cta/Ata	-4,27	0	0	probably_damaging	1	neutral	0,26	neutral	4,16	neutral	-2,65	neutral	-0,02	neutral_impact	0,4	neutral	0,87	neutral	0,84	neutral	1,37	12,65	0,36	0,65	disease	0,63	neutral	0,08	neutral	0,32	neutral	0,37	3	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,04	medium_impact	-0,76	0,5	0,9	10,18	13,06	N	0,52	P	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8426	8426	T	C	MI.1570	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	61	21	F	L	Ttc/Ctc	-2,19	0	0	probably_damaging	0,96	neutral	1	neutral	2,28	deleterious	-4,27	deleterious	-5,44	low_impact	1,92	neutral	0,99	neutral	0,62	deleterious	3,82	23,4	0,39211194	0,85	disease	0,55	neutral	0,4	disease	0,58	neutral	0,24	5	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,74	low_impact	-2,07	high_impact	1,98	medium_impact	0,55	0,43	0,85	NA	NA	N	0,36	N	0,75	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10474	10474	C	A	MI.15700	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	5	2	P	H	cCc/cAc	-2,48	0	0	possibly_damaging	0,87	neutral	0,43	neutral	1,95	neutral	-1,9	deleterious	-3,94	low_impact	1,36	neutral	0,89	neutral	0,67	deleterious	3,45	23	0,59	0,65	neutral	0,33	neutral	0,2	neutral	0,22	neutral	0,38	3	neutral	0,87	neutral	0,28	neutral	-3	deleterious	0,57	low_impact	-1,56	medium_impact	0,14	medium_impact	0	0,41	0,8	29,59	16,37	N	0,41	N	0,57	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10474	10474	C	T	MI.15701	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	5	2	P	L	cCc/cTc	-2,48	0	0	benign	0,03	neutral	1	neutral	2	neutral	-0,61	deleterious	-4,44	neutral_impact	0,58	neutral	0,81	neutral	0,51	neutral	1,14	11,45	0,54	0,6	neutral	0,21	neutral	0,25	neutral	0,3	neutral	0,43	1	neutral	0,03	deleterious	0,99	neutral	-6	neutral	0,11	medium_impact	0,58	high_impact	1,88	medium_impact	-0,65	0,74	0,85	29,59	16,37	N	0,23	N	0,63	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10476	10476	C	T	MI.15702	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	7	3	L	F	Ctc/Ttc	-11,7	0	0	benign	0,01	neutral	0,76	neutral	1,81	neutral	-2,02	neutral	-1	neutral_impact	0	neutral	0,9	neutral	0,94	neutral	-0,45	0,29	0,55	0,6	neutral	0,24	neutral	0,19	neutral	0,28	neutral	0,34	3	neutral	0,21	deleterious	0,88	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,49	low_impact	-1,14	0,71	0,85	31,63	22,49	N	0,43	N	0,29	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10476	10476	C	G	MI.15703	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	7	3	L	V	Ctc/Gtc	-11,7	0	0	benign	0,01	neutral	0,52	neutral	1,9	neutral	-0,68	neutral	-0,24	neutral_impact	0	neutral	0,91	neutral	0,88	neutral	-0,59	0,13	0,61	0,65	neutral	0,25	neutral	0,21	neutral	0,38	neutral	0,36	3	neutral	0,46	deleterious	0,76	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,23	low_impact	-1,14	0,6	0,8	31,63	22,49	N	0,38	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10476	10476	C	A	MI.15704	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	7	3	L	I	Ctc/Atc	-11,7	0	0	benign	0,01	neutral	0,56	neutral	1,88	neutral	-1,02	neutral	-0,1	neutral_impact	0	neutral	0,97	neutral	0,97	deleterious	0,19	4,55	0,54	0,6	neutral	0,28	neutral	0,19	neutral	0,28	neutral	0,35	3	neutral	0,43	deleterious	0,78	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,27	low_impact	-1,14	0,7	0,85	31,63	22,49	N	0,37	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10477	10477	T	C	MI.15705	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	8	3	L	P	cTc/cCc	-5,47	0	0	benign	0,01	neutral	0,4	neutral	1,77	neutral	-2,61	neutral	-0,66	neutral_impact	0	neutral	0,9	neutral	0,96	deleterious	0,2	4,65	0,52	0,6	neutral	0,31	neutral	0,11	neutral	0,44	neutral	0,3	4	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,11	low_impact	-1,14	0,55	0,8	31,63	22,49	N	0,45	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10477	10477	T	A	MI.15706	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	8	3	L	H	cTc/cAc	-5,47	0	0	possibly_damaging	0,66	neutral	0,48	neutral	1,77	neutral	-2,46	neutral	-2,06	neutral_impact	0	neutral	0,81	neutral	0,75	deleterious	1,88	15,46	0,38	0,5	disease	0,61	neutral	0,37	neutral	0,35	disease	0,61	2	neutral	0,64	neutral	0,41	neutral	-3	deleterious	0,68	low_impact	-1,07	medium_impact	0,19	low_impact	-1,14	0,63	0,8	31,63	22,49	N	0,27	N	0,47	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10477	10477	T	G	MI.15707	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	8	3	L	R	cTc/cGc	-5,47	0	0	possibly_damaging	0,55	neutral	0,33	neutral	1,79	neutral	-1,26	neutral	-2,03	neutral_impact	0	neutral	0,71	neutral	0,47	deleterious	2,07	16,69	0,4	0,5	disease	0,52	disease	0,67	neutral	0,49	disease	0,55	1	neutral	0,66	neutral	0,39	neutral	-3	deleterious	0,59	medium_impact	-0,88	medium_impact	0,04	low_impact	-1,14	0,63	0,8	31,63	22,49	N	0,27	N	0,39	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10479	10479	A	C	MI.15708	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	10	4	I	L	Att/Ctt	-7,78	0	0	benign	0,26	neutral	1	neutral	2,14	neutral	0,78	neutral	-1,44	low_impact	1,01	neutral	0,88	neutral	0,81	deleterious	0,24	5,14	0,48	0,55	neutral	0,12	neutral	0,2	neutral	0,37	neutral	0,34	3	neutral	0,26	deleterious	0,87	neutral	-6	neutral	0,13	medium_impact	-0,39	high_impact	1,88	medium_impact	-0,29	0,52	0,8	27,55	22,37	N	0,29	N	0,31	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10479	10479	A	G	MI.15709	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	10	4	I	V	Att/Gtt	-7,78	0	0	benign	0,05	neutral	0,58	neutral	1,93	neutral	-0,56	neutral	-0,29	neutral_impact	0,36	neutral	0,96	neutral	1	neutral	-0,98	0,02	0,75	0,8	neutral	0,12	neutral	0,06	neutral	0,39	neutral	0,24	5	neutral	0,36	deleterious	0,77	neutral	-6	neutral	0,09	medium_impact	0,37	medium_impact	0,29	medium_impact	-0,84	0,22	0,8	27,55	22,37	N	0,36	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8426	8426	T	G	MI.1571	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	61	21	F	V	Ttc/Gtc	-2,19	0	0	probably_damaging	0,97	neutral	0,13	neutral	1,81	deleterious	-5,39	deleterious	-6,36	medium_impact	3,32	neutral	1	neutral	0,5	deleterious	3,88	23,5	0,25207871	0,85	disease	0,72	neutral	0,47	disease	0,69	neutral	0,34	3	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,8	low_impact	-2,19	medium_impact	-0,18	medium_impact	1,75	0,5	0,85	NA	NA	N	0,54	P	0,83	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10479	10479	A	T	MI.15710	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	10	4	I	F	Att/Ttt	-7,78	0	0	probably_damaging	0,91	neutral	1	neutral	1,88	neutral	-1,22	deleterious	-3,19	low_impact	1,19	neutral	0,78	neutral	0,42	deleterious	3,52	23,1	0,54	0,6	neutral	0,35	neutral	0,41	disease	0,54	neutral	0,46	1	neutral	0,91	deleterious	0,55	neutral	-2	deleterious	0,57	low_impact	-1,72	high_impact	1,88	medium_impact	-0,14	0,53	0,8	27,55	22,37	N	0,2	N	0,45	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10480	10480	T	C	MI.15711	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	11	4	I	T	aTt/aCt	-0,63	0	0	benign	0,11	neutral	0,6	neutral	1,88	neutral	-1,26	deleterious	-2,63	neutral_impact	-0,26	neutral	0,91	neutral	0,98	neutral	-0,39	0,41	0,71	0,75	neutral	0,18	neutral	0,19	neutral	0,4	neutral	0,34	3	neutral	0,3	deleterious	0,75	neutral	-6	neutral	0,12	medium_impact	0,03	medium_impact	0,31	low_impact	-1,36	0,37	0,8	27,55	22,37	N	0,36	N	0,05	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10480	10480	T	G	MI.15712	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	11	4	I	S	aTt/aGt	-0,63	0	0	possibly_damaging	0,76	neutral	0,61	neutral	1,86	neutral	-1,59	deleterious	-4,12	medium_impact	2,16	neutral	0,83	neutral	0,68	deleterious	2,62	20,3	0,55	0,6	neutral	0,35	neutral	0,46	disease	0,51	neutral	0,47	1	neutral	0,72	neutral	0,43	NA	0	neutral	0,41	low_impact	-1,26	medium_impact	0,32	medium_impact	0,67	0,44	0,8	27,55	22,37	N	0,28	N	0,4	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10480	10480	T	A	MI.15713	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	11	4	I	N	aTt/aAt	-0,63	0	0	probably_damaging	0,91	neutral	0,27	neutral	1,8	deleterious	-3,79	deleterious	-5,05	medium_impact	2,16	neutral	0,84	neutral	0,46	deleterious	4,15	23,8	0,52	0,6	disease	0,52	disease	0,53	neutral	0,47	disease	0,52	0	neutral	0,93	neutral	0,18	deleterious	1	deleterious	0,63	low_impact	-1,72	medium_impact	-0,03	medium_impact	0,67	0,57	0,8	27,55	22,37	N	0,36	N	0,6	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10481	10481	T	A	MI.15714	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	12	4	I	M	atT/atA	0,52	0	0	benign	0,4	neutral	0,52	neutral	1,87	neutral	-1,4	neutral	-1,88	low_impact	1,01	neutral	0,91	neutral	0,94	deleterious	2,01	16,31	0,65	0,7	neutral	0,35	neutral	0,18	neutral	0,37	neutral	0,29	4	neutral	0,42	deleterious	0,56	neutral	-6	neutral	0,24	medium_impact	-0,64	medium_impact	0,23	medium_impact	-0,29	0,56	0,8	27,55	22,37	N	0,43	N	0,5	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10481	10481	T	G	MI.15715	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	12	4	I	M	atT/atG	0,52	0	0	benign	0,4	neutral	0,52	neutral	1,87	neutral	-1,4	neutral	-1,88	low_impact	1,01	neutral	0,91	neutral	0,94	neutral	1,78	14,85	0,65	0,7	neutral	0,35	neutral	0,18	neutral	0,37	neutral	0,29	4	neutral	0,42	deleterious	0,56	neutral	-6	neutral	0,24	medium_impact	-0,64	medium_impact	0,23	medium_impact	-0,29	0,56	0,8	27,55	22,37	N	0,44	N	0,5	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10482	10482	T	G	MI.15716	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	13	5	Y	D	Tac/Gac	-9,16	0	0	probably_damaging	0,96	neutral	0,2	neutral	1,93	neutral	-2,8	deleterious	-5,27	low_impact	1,87	neutral	0,66	neutral	0,4	deleterious	3,73	23,3	0,47	0,55	disease	0,81	disease	0,7	disease	0,64	disease	0,75	5	neutral	0,97	neutral	0,12	neutral	-2	deleterious	0,78	low_impact	-2,07	medium_impact	-0,12	medium_impact	0,43	0,49	0,8	34,69	11,85	N	0,27	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10482	10482	T	A	MI.15717	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	13	5	Y	N	Tac/Aac	-9,16	0	0	probably_damaging	0,92	neutral	0,31	neutral	1,93	neutral	-2,04	deleterious	-4,27	neutral_impact	0,12	neutral	0,84	neutral	0,87	deleterious	2,46	19,2	0,54	0,6	disease	0,72	neutral	0,49	disease	0,53	disease	0,58	2	neutral	0,93	neutral	0,2	neutral	-2	deleterious	0,72	low_impact	-1,78	medium_impact	0,02	low_impact	-1,04	0,37	0,8	34,69	11,85	N	0,32	N	0,55	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10482	10482	T	C	MI.15718	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	13	5	Y	H	Tac/Cac	-9,16	0	0	benign	0,25	neutral	0,54	neutral	1,96	neutral	-1,56	deleterious	-2,6	neutral_impact	0,17	neutral	0,84	neutral	0,97	neutral	-1,18	0,01	0,63	0,7	neutral	0,17	neutral	0,1	neutral	0,45	neutral	0,25	5	neutral	0,35	deleterious	0,65	neutral	-6	neutral	0,15	medium_impact	-0,37	medium_impact	0,25	medium_impact	-1	0,43	0,8	34,69	11,85	N	0,31	N	0,35	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10483	10483	A	T	MI.15719	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	14	5	Y	F	tAc/tTc	-0,4	0	0	benign	0,17	neutral	0,7	neutral	1,96	neutral	0,12	neutral	-1,39	low_impact	0,83	neutral	0,92	neutral	0,97	deleterious	0,11	3,74	0,53	0,6	neutral	0,19	neutral	0,37	neutral	0,46	neutral	0,44	1	neutral	0,18	deleterious	0,77	neutral	-6	neutral	0,17	medium_impact	-0,17	medium_impact	0,41	medium_impact	-0,44	0,47	0,8	34,69	11,85	N	0,33	N	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8427	8427	T	C	MI.1572	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	62	21	F	S	tTc/tCc	0,82	0	0	probably_damaging	0,98	neutral	0,3	neutral	1,77	deleterious	-6,46	deleterious	-7,42	low_impact	1,82	neutral	1	neutral	0,41	deleterious	4,16	23,8	0,27134083	0,85	disease	0,82	neutral	0,45	disease	0,67	neutral	0,31	4	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,77	low_impact	-2,36	medium_impact	0,08	medium_impact	0,46	0,39	0,85	NA	NA	N	0,51	P	0,86	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10483	10483	A	G	MI.15720	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	14	5	Y	C	tAc/tGc	-0,4	0	0	probably_damaging	0,98	neutral	0,18	neutral	1,91	deleterious	-3,68	deleterious	-4,54	low_impact	1,87	neutral	0,64	neutral	0,51	deleterious	3,38	22,9	0,53	0,6	disease	0,85	disease	0,61	disease	0,64	disease	0,73	5	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,76	low_impact	-2,35	medium_impact	-0,16	medium_impact	0,43	0,2	0,8	34,69	11,85	N	0,32	N	0,78	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10483	10483	A	C	MI.15721	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	14	5	Y	S	tAc/tCc	-0,4	0	0	probably_damaging	0,94	neutral	0,4	neutral	2,02	neutral	-1,68	deleterious	-3,88	neutral_impact	0,63	neutral	0,86	neutral	0,85	deleterious	2,32	18,28	0,47	0,55	disease	0,67	neutral	0,43	disease	0,57	disease	0,64	3	neutral	0,94	neutral	0,23	neutral	-2	deleterious	0,7	low_impact	-1,9	medium_impact	0,11	medium_impact	-0,61	0,37	0,8	34,69	11,85	N	0,32	N	0,71	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10485	10485	A	T	MI.15722	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	16	6	M	L	Ata/Tta	-7,32	0	0	benign	0,01	neutral	1	neutral	2,3	neutral	2,74	neutral	-0,17	neutral_impact	-0,9	neutral	0,85	neutral	0,99	neutral	-1,45	0	0,75	0,8	neutral	0,15	neutral	0,22	neutral	0,49	neutral	0,39	2	neutral	0,01	deleterious	1	neutral	-6	neutral	0,1	medium_impact	1,03	high_impact	1,88	low_impact	-1,89	0,71	0,85	23,47	19,01	N	0,33	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10485	10485	A	G	MI.15723	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	16	6	M	V	Ata/Gta	-7,32	0	0	benign	0,01	neutral	0,33	neutral	2,1	neutral	1,51	neutral	-0,66	neutral_impact	0,38	neutral	0,92	neutral	0,97	neutral	-0,46	0,27	0,66	0,7	neutral	0,15	neutral	0,4	disease	0,55	neutral	0,47	1	neutral	0,66	deleterious	0,66	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,04	medium_impact	-0,82	0,69	0,85	23,47	19,01	N	0,31	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10485	10485	A	C	MI.15724	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	16	6	M	L	Ata/Cta	-7,32	0	0	benign	0,01	neutral	1	neutral	2,3	neutral	2,74	neutral	-0,17	neutral_impact	-0,9	neutral	0,85	neutral	0,99	neutral	-1,49	0	0,75	0,8	neutral	0,15	neutral	0,22	neutral	0,49	neutral	0,39	2	neutral	0,01	deleterious	1	neutral	-6	neutral	0,1	medium_impact	1,03	high_impact	1,88	low_impact	-1,89	0,71	0,85	23,47	19,01	N	0,33	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10486	10486	T	C	MI.15725	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	17	6	M	T	aTa/aCa	-2,24	0	0	benign	0,01	neutral	0,15	neutral	2,04	neutral	0,8	neutral	-2,49	neutral_impact	-0,4	neutral	0,88	neutral	0,96	neutral	-0,28	0,75	0,58	0,65	neutral	0,24	neutral	0,32	disease	0,55	neutral	0,47	1	neutral	0,85	deleterious	0,57	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	-0,21	low_impact	-1,47	0,49	0,8	23,47	19,01	N	0,37	N	0,57	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10486	10486	T	A	MI.15726	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	17	6	M	K	aTa/aAa	-2,24	0	0	benign	0,26	deleterious	0,04	neutral	1,97	neutral	-1,23	deleterious	-3,96	low_impact	1,39	neutral	0,71	neutral	0,53	deleterious	2,21	17,59	0,37	0,5	neutral	0,4	disease	0,65	disease	0,74	disease	0,76	5	neutral	0,95	neutral	0,39	neutral	-2	neutral	0,34	medium_impact	-0,39	medium_impact	-0,56	medium_impact	0,03	0,73	0,85	23,47	19,01	N	0,37	N	0,84	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10487	10487	A	T	MI.15727	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	18	6	M	I	atA/atT	0,98	0	0	benign	0,01	neutral	0,67	neutral	2,12	neutral	1,67	neutral	-0,21	neutral_impact	-0,32	neutral	0,91	neutral	0,98	neutral	-0,47	0,26	0,65	0,7	neutral	0,12	neutral	0,31	disease	0,51	neutral	0,44	1	neutral	0,32	deleterious	0,83	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	0,38	low_impact	-1,41	0,71	0,85	23,47	19,01	N	0,36	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10487	10487	A	C	MI.15728	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	18	6	M	I	atA/atC	0,98	0	0	benign	0,01	neutral	0,67	neutral	2,12	neutral	1,67	neutral	-0,21	neutral_impact	-0,32	neutral	0,91	neutral	0,98	neutral	-0,55	0,17	0,65	0,7	neutral	0,12	neutral	0,31	disease	0,51	neutral	0,44	1	neutral	0,32	deleterious	0,83	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	0,38	low_impact	-1,41	0,71	0,85	23,47	19,01	N	0,36	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10488	10488	A	G	MI.15729	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	19	7	N	D	Aat/Gat	-3,17	0	0	possibly_damaging	0,83	neutral	0,2	neutral	1,93	neutral	-2,97	deleterious	-4,77	medium_impact	3,23	neutral	0,76	neutral	0,52	deleterious	3,66	23,2	0,73	0,75	neutral	0,36	disease	0,69	disease	0,58	disease	0,71	4	neutral	0,9	neutral	0,19	NA	0	deleterious	0,63	low_impact	-1,43	medium_impact	-0,12	medium_impact	1,57	0,7	0,85	54,08	12,33	N	0,47	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8427	8427	T	A	MI.1573	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	62	21	F	Y	tTc/tAc	0,82	0	0	probably_damaging	0,96	neutral	0,16	neutral	1,77	deleterious	-4,27	neutral	-2	medium_impact	2,31	neutral	0,99	neutral	0,65	deleterious	2,56	19,86	0,22453471	0,85	neutral	0,5	neutral	0,11	disease	0,58	neutral	0,05	9	neutral	0,98	neutral	0,1	deleterious	1	deleterious	0,7	low_impact	-2,07	medium_impact	-0,12	medium_impact	0,88	0,64	0,85	NA	NA	P	0,59	P	0,35	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10488	10488	A	C	MI.15730	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	19	7	N	H	Aat/Cat	-3,17	0	0	probably_damaging	0,98	neutral	0,54	neutral	1,94	neutral	-2,47	deleterious	-4,62	medium_impact	2,89	neutral	0,83	neutral	0,5	deleterious	3,03	22,3	0,57	0,65	disease	0,53	disease	0,68	disease	0,53	disease	0,63	3	neutral	0,97	neutral	0,28	deleterious	1	deleterious	0,71	low_impact	-2,35	medium_impact	0,25	medium_impact	1,28	0,75	0,85	54,08	12,33	N	0,22	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10488	10488	A	T	MI.15731	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	19	7	N	Y	Aat/Tat	-3,17	0	0	probably_damaging	0,98	neutral	1	neutral	1,95	neutral	-1,29	deleterious	-7,29	medium_impact	2,68	neutral	0,84	neutral	0,51	deleterious	3,65	23,2	0,54	0,6	disease	0,56	disease	0,76	disease	0,54	disease	0,7	4	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,74	low_impact	-2,35	high_impact	1,88	medium_impact	1,11	0,62	0,8	54,08	12,33	N	0,19	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10489	10489	A	T	MI.15732	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	20	7	N	I	aAt/aTt	3,06	0,34	0	probably_damaging	0,92	neutral	0,4	neutral	2,08	neutral	1,06	deleterious	-8,45	medium_impact	2,08	neutral	0,8	neutral	0,65	deleterious	3,63	23,2	0,49	0,55	neutral	0,43	disease	0,82	neutral	0,46	disease	0,6	2	neutral	0,92	neutral	0,24	deleterious	1	deleterious	0,72	low_impact	-1,78	medium_impact	0,11	medium_impact	0,61	0,55	0,8	54,08	12,33	N	0,32	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10489	10489	A	G	MI.15733	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	20	7	N	S	aAt/aGt	3,06	0,34	0	benign	0,26	neutral	0,42	neutral	2,02	neutral	0,36	deleterious	-4,71	low_impact	1,44	neutral	0,83	neutral	0,73	neutral	-0,92	0,02	0,85	0,85	neutral	0,12	neutral	0,2	neutral	0,46	neutral	0,34	3	neutral	0,49	deleterious	0,58	neutral	-6	neutral	0,22	medium_impact	-0,39	medium_impact	0,13	medium_impact	0,07	0,56	0,8	54,08	12,33	N	0,37	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10489	10489	A	C	MI.15734	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	20	7	N	T	aAt/aCt	3,06	0,34	0	benign	0,26	neutral	0,4	neutral	2,19	neutral	1,9	deleterious	-5,58	low_impact	1,62	neutral	0,77	neutral	0,69	deleterious	0,22	4,89	0,66	0,7	neutral	0,32	neutral	0,39	neutral	0,45	neutral	0,45	1	neutral	0,52	deleterious	0,57	neutral	-6	deleterious	0,59	medium_impact	-0,39	medium_impact	0,11	medium_impact	0,22	0,8	0,85	54,08	12,33	N	0,37	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10490	10490	T	G	MI.15735	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	21	7	N	K	aaT/aaG	1,44	0,31	0	possibly_damaging	0,83	neutral	0,29	neutral	1,94	neutral	-1,81	deleterious	-5,69	medium_impact	3,23	neutral	0,79	neutral	0,48	deleterious	3,67	23,2	0,79	0,8	neutral	0,29	disease	0,78	disease	0,59	disease	0,74	5	neutral	0,87	neutral	0,23	NA	0	deleterious	0,66	low_impact	-1,43	medium_impact	-0,01	medium_impact	1,57	0,81	0,85	54,08	12,33	N	0,39	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10490	10490	T	A	MI.15736	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	21	7	N	K	aaT/aaA	1,44	0,31	0	possibly_damaging	0,83	neutral	0,29	neutral	1,94	neutral	-1,81	deleterious	-5,69	medium_impact	3,23	neutral	0,79	neutral	0,48	deleterious	3,99	23,6	0,79	0,8	neutral	0,29	disease	0,78	disease	0,59	disease	0,74	5	neutral	0,87	neutral	0,23	NA	0	deleterious	0,66	low_impact	-1,43	medium_impact	-0,01	medium_impact	1,57	0,81	0,85	54,08	12,33	N	0,41	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10491	10491	A	T	MI.15737	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	22	8	I	F	Att/Ttt	-8,93	0	0	possibly_damaging	0,87	neutral	0,94	neutral	1,79	neutral	-1,61	deleterious	-3,01	low_impact	1,74	neutral	0,72	neutral	0,83	deleterious	0,56	7,84	0,63	0,7	neutral	0,15	neutral	0,18	neutral	0,35	neutral	0,22	6	neutral	0,86	deleterious	0,54	neutral	-3	deleterious	0,6	low_impact	-1,56	medium_impact	0,87	medium_impact	0,32	0,81	0,85	27,55	11,42	N	0,34	N	0,65	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10491	10491	A	G	MI.15738	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	22	8	I	V	Att/Gtt	-8,93	0	0	benign	0,05	neutral	0,4	neutral	1,86	neutral	-0,94	neutral	-0,6	low_impact	1,45	neutral	0,84	neutral	0,94	neutral	-0,63	0,11	0,69	0,75	neutral	0,21	neutral	0,27	neutral	0,48	neutral	0,44	1	neutral	0,56	deleterious	0,68	neutral	-6	neutral	0,13	medium_impact	0,37	medium_impact	0,11	medium_impact	0,08	0,77	0,85	27,55	11,42	N	0,37	N	0,52	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10491	10491	A	C	MI.15739	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	22	8	I	L	Att/Ctt	-8,93	0	0	benign	0,05	neutral	1	neutral	1,85	neutral	-1	neutral	-0,8	neutral_impact	0,22	neutral	0,77	neutral	0,95	neutral	-0,08	1,87	0,37	0,5	neutral	0,11	neutral	0,33	neutral	0,33	neutral	0,44	1	neutral	0,05	deleterious	0,98	neutral	-6	neutral	0,35	medium_impact	0,37	high_impact	1,88	medium_impact	-0,95	0,75	0,85	27,55	11,42	N	0,28	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8427	8427	T	G	MI.1574	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	62	21	F	C	tTc/tGc	0,82	0	0	probably_damaging	1	deleterious	0,04	neutral	1,73	deleterious	-7,99	deleterious	-7,39	medium_impact	3,12	neutral	0,99	neutral	0,38	deleterious	3,96	23,6	0,21080113	0,85	disease	0,92	neutral	0,46	disease	0,71	neutral	0,37	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,82	low_impact	-3,6	medium_impact	-0,49	medium_impact	1,58	0,32	0,85	NA	NA	N	0,53	P	0,92	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10492	10492	T	A	MI.15740	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	23	8	I	N	aTt/aAt	-0,86	0	0	possibly_damaging	0,87	neutral	0,15	neutral	1,71	deleterious	-3,97	deleterious	-5,75	medium_impact	2,25	neutral	0,71	neutral	0,53	deleterious	3,94	23,5	0,44	0,55	disease	0,58	disease	0,68	disease	0,59	disease	0,72	4	neutral	0,94	neutral	0,14	NA	0	deleterious	0,72	low_impact	-1,56	medium_impact	-0,21	medium_impact	0,75	0,77	0,85	27,55	11,42	N	0,34	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10492	10492	T	C	MI.15741	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	23	8	I	T	aTt/aCt	-0,86	0	0	benign	0,13	neutral	0,29	neutral	1,76	neutral	-2,24	deleterious	-3,78	low_impact	1,71	neutral	0,84	neutral	0,9	neutral	1,17	11,59	0,58	0,65	neutral	0,36	neutral	0,43	disease	0,58	neutral	0,48	0	neutral	0,66	deleterious	0,58	neutral	-6	neutral	0,24	medium_impact	-0,05	medium_impact	-0,01	medium_impact	0,3	0,76	0,85	27,55	11,42	N	0,43	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10492	10492	T	G	MI.15742	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	23	8	I	S	aTt/aGt	-0,86	0	0	benign	0,18	neutral	0,32	neutral	1,85	neutral	-1,02	deleterious	-4,72	medium_impact	2,6	neutral	0,68	neutral	0,67	deleterious	2,16	17,25	0,45	0,55	neutral	0,41	disease	0,65	neutral	0,5	disease	0,55	1	neutral	0,62	deleterious	0,57	neutral	-3	deleterious	0,61	medium_impact	-0,2	medium_impact	0,03	medium_impact	1,04	0,75	0,85	27,55	11,42	N	0,42	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10493	10493	T	G	MI.15743	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	24	8	I	M	atT/atG	3,52	0,28	0	probably_damaging	0,91	neutral	0,34	neutral	1,73	neutral	-2,79	neutral	-1,38	low_impact	1,71	neutral	0,82	neutral	0,97	deleterious	1,94	15,84	0,58	0,65	neutral	0,35	neutral	0,37	neutral	0,45	neutral	0,47	1	neutral	0,92	neutral	0,22	neutral	-2	deleterious	0,65	low_impact	-1,72	medium_impact	0,05	medium_impact	0,3	0,86	0,9	27,55	11,42	N	0,46	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10493	10493	T	A	MI.15744	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	24	8	I	M	atT/atA	3,52	0,28	0	probably_damaging	0,91	neutral	0,34	neutral	1,73	neutral	-2,79	neutral	-1,38	low_impact	1,71	neutral	0,82	neutral	0,97	deleterious	2,26	17,93	0,58	0,65	neutral	0,35	neutral	0,37	neutral	0,45	neutral	0,47	1	neutral	0,92	neutral	0,22	neutral	-2	deleterious	0,65	low_impact	-1,72	medium_impact	0,05	medium_impact	0,3	0,86	0,9	27,55	11,42	N	0,46	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10494	10494	A	G	MI.15745	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	25	9	M	V	Ata/Gta	-7,09	0	0	benign	0	neutral	0,52	neutral	2,04	neutral	0,53	neutral	-0,82	low_impact	1,08	neutral	0,81	neutral	0,84	neutral	-1,08	0,01	0,65	0,7	neutral	0,14	disease	0,51	disease	0,57	disease	0,66	3	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,23	medium_impact	-0,23	0,38	0,8	29,59	17,1	N	0,26	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10494	10494	A	C	MI.15746	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	25	9	M	L	Ata/Cta	-7,09	0	0	benign	0	neutral	1	neutral	2,09	neutral	1,04	neutral	-0,61	neutral_impact	0,16	neutral	0,77	neutral	0,98	neutral	-0,87	0,03	0,58	0,65	neutral	0,13	neutral	0,47	neutral	0,41	neutral	0,43	1	neutral	0	deleterious	1	neutral	-6	neutral	0,11	medium_impact	1,95	high_impact	1,88	low_impact	-1	0,46	0,8	29,59	17,1	N	0,28	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10494	10494	A	T	MI.15747	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	25	9	M	L	Ata/Tta	-7,09	0	0	benign	0	neutral	1	neutral	2,09	neutral	1,04	neutral	-0,61	neutral_impact	0,16	neutral	0,77	neutral	0,98	neutral	-0,8	0,04	0,58	0,65	neutral	0,13	neutral	0,47	neutral	0,41	neutral	0,43	1	neutral	0	deleterious	1	neutral	-6	neutral	0,11	medium_impact	1,95	high_impact	1,88	low_impact	-1	0,46	0,8	29,59	17,1	N	0,28	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10495	10495	T	C	MI.15748	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	26	9	M	T	aTa/aCa	-1,09	0	0	benign	0	neutral	0,41	neutral	2	neutral	0,01	neutral	-1,78	low_impact	0,8	neutral	0,84	neutral	0,99	neutral	-1,09	0,01	0,65	0,7	neutral	0,12	neutral	0,26	neutral	0,47	neutral	0,42	2	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,09	medium_impact	1,95	medium_impact	0,12	medium_impact	-0,47	0,31	0,8	29,59	17,1	N	0,34	N	0,04	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10495	10495	T	A	MI.15749	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	26	9	M	K	aTa/aAa	-1,09	0	0	benign	0,11	neutral	0,16	neutral	1,93	neutral	-2,17	deleterious	-3,67	medium_impact	2,44	neutral	0,81	neutral	0,53	deleterious	0,35	6,12	0,33	0,5	neutral	0,35	disease	0,75	disease	0,68	disease	0,75	5	neutral	0,82	deleterious	0,53	neutral	-3	neutral	0,27	medium_impact	0,03	medium_impact	-0,19	medium_impact	0,91	0,48	0,8	29,59	17,1	N	0,34	N	0,6	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8428	8428	C	A	MI.1575	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	63	21	F	L	ttC/ttA	1,29	0	0	probably_damaging	0,96	neutral	1	neutral	2,28	deleterious	-4,27	deleterious	-5,44	low_impact	1,92	neutral	0,99	neutral	0,62	deleterious	4,52	24,3	0,39211194	0,85	disease	0,55	neutral	0,4	disease	0,58	neutral	0,24	5	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,74	low_impact	-2,07	high_impact	1,98	medium_impact	0,55	0,43	0,85	NA	NA	N	0,35	N	0,75	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10496	10496	A	T	MI.15750	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	27	9	M	I	atA/atT	-1,09	0	0	benign	0	neutral	0,56	neutral	2,1	neutral	1,07	neutral	-0,61	neutral_impact	0,08	neutral	0,78	neutral	0,99	neutral	-0,41	0,37	0,49	0,55	neutral	0,11	neutral	0,4	neutral	0,39	neutral	0,43	1	neutral	0,44	deleterious	0,78	neutral	-6	neutral	0,11	medium_impact	1,95	medium_impact	0,27	low_impact	-1,07	0,54	0,8	29,59	17,1	N	0,33	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10496	10496	A	C	MI.15751	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	27	9	M	I	atA/atC	-1,09	0	0	benign	0	neutral	0,56	neutral	2,1	neutral	1,07	neutral	-0,61	neutral_impact	0,08	neutral	0,78	neutral	0,99	neutral	-0,45	0,29	0,49	0,55	neutral	0,11	neutral	0,4	neutral	0,39	neutral	0,43	1	neutral	0,44	deleterious	0,78	neutral	-6	neutral	0,11	medium_impact	1,95	medium_impact	0,27	low_impact	-1,07	0,54	0,8	29,59	17,1	N	0,33	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10497	10497	C	G	MI.15752	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	28	10	L	V	Cta/Gta	-7,78	0	0	possibly_damaging	0,9	neutral	0,46	neutral	1,78	neutral	-1,21	neutral	-1,66	low_impact	1,46	neutral	0,78	neutral	0,93	neutral	1,61	13,93	0,5	0,6	neutral	0,16	neutral	0,49	neutral	0,41	neutral	0,45	1	neutral	0,89	neutral	0,28	neutral	-3	deleterious	0,65	low_impact	-1,68	medium_impact	0,17	medium_impact	0,09	0,58	0,8	8,16	13,61	N	0,28	N	0,24	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10497	10497	C	A	MI.15753	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	28	10	L	M	Cta/Ata	-7,78	0	0	possibly_damaging	0,76	neutral	0,36	neutral	1,67	neutral	-2,66	neutral	-0,75	neutral_impact	0,77	neutral	0,8	neutral	0,97	deleterious	1,96	15,94	0,32	0,5	neutral	0,16	neutral	0,2	neutral	0,37	neutral	0,36	3	neutral	0,78	neutral	0,3	neutral	-3	deleterious	0,64	low_impact	-1,26	medium_impact	0,07	medium_impact	-0,49	0,7	0,85	8,16	13,61	N	0,35	N	0,05	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10498	10498	T	A	MI.15754	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	29	10	L	Q	cTa/cAa	-3,63	0	0	possibly_damaging	0,63	neutral	0,15	neutral	1,61	deleterious	-4,7	deleterious	-4,24	high_impact	3,51	neutral	0,76	neutral	0,29	deleterious	3,85	23,4	0,22	0,45	neutral	0,46	disease	0,65	disease	0,64	disease	0,73	5	neutral	0,86	neutral	0,26	deleterious	1	deleterious	0,72	low_impact	-1,02	medium_impact	-0,21	medium_impact	1,8	0,76	0,85	8,16	13,61	N	0,39	N	0,76	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10498	10498	T	G	MI.15755	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	29	10	L	R	cTa/cGa	-3,63	0	0	probably_damaging	0,97	neutral	0,18	neutral	1,62	deleterious	-4,52	deleterious	-4,54	high_impact	3,51	neutral	0,72	damaging	0,21	deleterious	3,93	23,5	0,22	0,45	neutral	0,44	disease	0,88	disease	0,74	disease	0,82	6	deleterious	0,98	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-2,19	medium_impact	-0,16	medium_impact	1,8	0,74	0,85	8,16	13,61	N	0,35	N	0,81	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10498	10498	T	C	MI.15756	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	29	10	L	P	cTa/cCa	-3,63	0	0	probably_damaging	0,99	neutral	0,16	neutral	1,61	deleterious	-5,1	deleterious	-5,27	high_impact	3,51	neutral	0,67	damaging	0,19	deleterious	3,66	23,2	0,17	0,45	disease	0,54	disease	0,86	disease	0,73	disease	0,81	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,8	low_impact	-2,63	medium_impact	-0,19	medium_impact	1,8	0,66	0,8	8,16	13,61	N	0,3	N	0,95	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10500	10500	G	C	MI.15757	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	31	11	A	P	Gca/Cca	-1,09	0	0	probably_damaging	0,96	neutral	0,21	neutral	1,83	deleterious	-3,87	deleterious	-4,91	medium_impact	2,62	damaging	0,6	neutral	0,33	deleterious	3,57	23,1	0,19	0,45	disease	0,73	disease	0,93	disease	0,74	disease	0,85	7	neutral	0,98	neutral	0,13	deleterious	1	deleterious	0,83	low_impact	-2,07	medium_impact	-0,11	medium_impact	1,06	0,82	0,85	56,12	11,69	N	0,31	N	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10500	10500	G	T	MI.15758	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	31	11	A	S	Gca/Tca	-1,09	0	0	benign	0,3	neutral	0,42	neutral	1,87	neutral	-1,69	deleterious	-2,92	medium_impact	2	neutral	0,82	neutral	0,63	neutral	1,73	14,56	0,58	0,65	disease	0,51	disease	0,75	neutral	0,43	disease	0,58	2	neutral	0,5	deleterious	0,56	neutral	-3	neutral	0,26	medium_impact	-0,47	medium_impact	0,13	medium_impact	0,54	0,73	0,85	56,12	11,69	N	0,29	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10500	10500	G	A	MI.15759	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	31	11	A	T	Gca/Aca	-1,09	0	0	benign	0,2	neutral	0,4	neutral	1,92	neutral	-0,9	deleterious	-3,83	low_impact	1,57	neutral	0,83	neutral	0,79	neutral	1,06	11,01	0,59	0,65	neutral	0,48	disease	0,66	neutral	0,44	neutral	0,47	1	neutral	0,52	deleterious	0,6	neutral	-6	neutral	0,25	medium_impact	-0,25	medium_impact	0,11	medium_impact	0,18	0,63	0,8	56,12	11,69	N	0,31	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8428	8428	C	G	MI.1576	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	63	21	F	L	ttC/ttG	1,29	0	0	probably_damaging	0,96	neutral	1	neutral	2,28	deleterious	-4,27	deleterious	-5,44	low_impact	1,92	neutral	0,99	neutral	0,62	deleterious	4,2	23,9	0,39211194	0,85	disease	0,55	neutral	0,4	disease	0,58	neutral	0,24	5	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,74	low_impact	-2,07	high_impact	1,98	medium_impact	0,55	0,43	0,85	NA	NA	N	0,34	N	0,75	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10501	10501	C	G	MI.15760	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	32	11	A	G	gCa/gGa	1,21	0,17	0	possibly_damaging	0,78	neutral	0,35	neutral	1,83	deleterious	-3,22	deleterious	-3,95	medium_impact	2,33	neutral	0,66	neutral	0,55	deleterious	3,52	23,1	0,39	0,5	disease	0,65	disease	0,82	disease	0,6	disease	0,7	4	neutral	0,81	neutral	0,29	NA	0	deleterious	0,63	low_impact	-1,31	medium_impact	0,06	medium_impact	0,82	0,8	0,85	56,12	11,69	N	0,34	N	0,81	polymorphism	0,96	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10501	10501	C	A	MI.15761	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	32	11	A	E	gCa/gAa	1,21	0,17	0	probably_damaging	0,91	neutral	0,27	neutral	1,83	deleterious	-3,52	deleterious	-4,91	high_impact	3,83	neutral	0,64	neutral	0,39	deleterious	4,3	24	0,26	0,45	disease	0,63	disease	0,93	disease	0,72	disease	0,81	6	neutral	0,93	neutral	0,18	deleterious	2	deleterious	0,76	low_impact	-1,72	medium_impact	-0,03	high_impact	2,07	0,64	0,8	56,12	11,69	N	0,43	N	0,97	polymorphism	0,92	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10501	10501	C	T	MI.15762	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	32	11	A	V	gCa/gTa	1,21	0,17	0	possibly_damaging	0,86	neutral	0,51	neutral	1,94	neutral	-0,64	deleterious	-3,92	low_impact	1,83	neutral	0,7	neutral	0,5	deleterious	4,09	23,7	0,69	0,75	neutral	0,27	disease	0,87	neutral	0,49	disease	0,73	5	neutral	0,85	neutral	0,33	neutral	-3	deleterious	0,62	low_impact	-1,53	medium_impact	0,22	medium_impact	0,4	0,68	0,85	56,12	11,69	N	0,36	N	0,88	polymorphism	0,96	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10503	10503	T	C	MI.15763	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	34	12	F	L	Ttt/Ctt	-6,63	0	0	benign	0,12	neutral	0,65	neutral	1,53	deleterious	-3,06	deleterious	-5,61	medium_impact	2,27	neutral	0,64	damaging	0,2	deleterious	1,97	16,02	0,49	0,55	disease	0,63	disease	0,93	disease	0,67	disease	0,72	4	neutral	0,24	deleterious	0,77	neutral	-3	neutral	0,31	medium_impact	-0,01	medium_impact	0,36	medium_impact	0,77	0,49	0,8	48,98	10,11	N	0,24	N	0,89	disease_causing	0,63	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10503	10503	T	A	MI.15764	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	34	12	F	I	Ttt/Att	-6,63	0	0	possibly_damaging	0,75	neutral	0,26	neutral	1,53	deleterious	-4,26	deleterious	-5,62	medium_impact	2,8	neutral	0,64	damaging	0,19	deleterious	4,04	23,7	0,27	0,45	disease	0,78	disease	0,95	disease	0,71	disease	0,84	7	neutral	0,82	neutral	0,26	NA	0	deleterious	0,68	low_impact	-1,24	medium_impact	-0,04	medium_impact	1,21	0,54	0,8	48,98	10,11	N	0,35	N	0,66	disease_causing	0,61	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10503	10503	T	G	MI.15765	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	34	12	F	V	Ttt/Gtt	-6,63	0	0	possibly_damaging	0,83	neutral	0,17	neutral	1,56	deleterious	-4,36	deleterious	-6,44	medium_impact	2,24	neutral	0,62	damaging	0,11	deleterious	3,78	23,4	0,31	0,45	disease	0,79	disease	0,95	disease	0,64	disease	0,79	6	neutral	0,91	neutral	0,17	NA	0	deleterious	0,72	low_impact	-1,43	medium_impact	-0,17	medium_impact	0,74	0,44	0,8	48,98	10,11	N	0,27	N	0,9	disease_causing	0,77	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10504	10504	T	C	MI.15766	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	35	12	F	S	tTt/tCt	5,83	1	0	probably_damaging	0,94	neutral	0,17	neutral	1,43	deleterious	-5,8	deleterious	-7,44	high_impact	3,6	neutral	0,64	damaging	0,14	deleterious	4,03	23,7	0,27	0,45	disease	0,86	disease	0,94	disease	0,71	disease	0,83	7	neutral	0,97	neutral	0,12	deleterious	2	deleterious	0,83	low_impact	-1,9	medium_impact	-0,17	medium_impact	1,88	0,34	0,8	48,98	10,11	P	0,61	P	0,97	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10504	10504	T	A	MI.15767	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	35	12	F	Y	tTt/tAt	5,83	1	0	benign	0,08	neutral	0,23	neutral	1,46	deleterious	-3,51	neutral	-1,8	medium_impact	2,08	neutral	0,77	neutral	0,83	deleterious	2,99	22,2	0,24	0,45	disease	0,56	disease	0,88	disease	0,65	disease	0,57	1	neutral	0,74	deleterious	0,58	neutral	-3	neutral	0,29	medium_impact	0,17	medium_impact	-0,08	medium_impact	0,61	0,55	0,8	48,98	10,11	P	0,59	P	0,85	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10504	10504	T	G	MI.15768	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	35	12	F	C	tTt/tGt	5,83	1	0	probably_damaging	0,98	neutral	0,06	neutral	1,41	deleterious	-7,21	deleterious	-7,44	high_impact	3,86	neutral	0,63	damaging	0,12	deleterious	3,85	23,4	0,28	0,45	disease	0,94	disease	0,94	disease	0,75	disease	0,84	7	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,85	low_impact	-2,35	medium_impact	-0,45	high_impact	2,1	0,27	0,8	48,98	10,11	P	0,58	P	0,96	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10505	10505	T	G	MI.15769	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	36	12	F	L	ttT/ttG	3,75	1	0	benign	0,12	neutral	0,65	neutral	1,53	deleterious	-3,06	deleterious	-5,61	medium_impact	2,27	neutral	0,64	damaging	0,2	deleterious	2,28	18,04	0,49	0,55	disease	0,63	disease	0,93	disease	0,67	disease	0,72	4	neutral	0,24	deleterious	0,77	neutral	-3	neutral	0,31	medium_impact	-0,01	medium_impact	0,36	medium_impact	0,77	0,49	0,8	48,98	10,11	N	0,49	N	0,89	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8429	8429	C	T	MI.1577	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	64	22	L	F	Ctc/Ttc	-7,04	0	0,01	probably_damaging	0,99	neutral	0,3	neutral	0,62	deleterious	-4,33	neutral	-1,66	low_impact	1,29	neutral	0,99	neutral	0,89	deleterious	3,78	23,4	0,45432647	0,85	neutral	0,49	neutral	0,14	neutral	0,3	neutral	0,12	8	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,73	low_impact	-2,65	medium_impact	0,08	medium_impact	0,01	0,49	0,85	14,71	8,52	N	0,53	P	0,36	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10505	10505	T	A	MI.15770	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	36	12	F	L	ttT/ttA	3,75	1	0	benign	0,12	neutral	0,65	neutral	1,53	deleterious	-3,06	deleterious	-5,61	medium_impact	2,27	neutral	0,64	damaging	0,2	deleterious	2,4	18,8	0,49	0,55	disease	0,63	disease	0,93	disease	0,67	disease	0,72	4	neutral	0,24	deleterious	0,77	neutral	-3	neutral	0,31	medium_impact	-0,01	medium_impact	0,36	medium_impact	0,77	0,49	0,8	48,98	10,11	N	0,49	N	0,89	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10506	10506	A	C	MI.15771	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	37	13	T	P	Acc/Ccc	-5,47	0	0	possibly_damaging	0,55	neutral	0,1	neutral	1,89	deleterious	-3,28	deleterious	-2,94	medium_impact	2,96	neutral	0,7	neutral	0,32	deleterious	2,97	22,1	0,19	0,45	neutral	0,49	disease	0,9	disease	0,7	disease	0,81	6	neutral	0,89	neutral	0,28	NA	0	deleterious	0,6	medium_impact	-0,88	medium_impact	-0,32	medium_impact	1,34	0,53	0,8	14,29	11,87	N	0,32	N	0,89	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10506	10506	A	G	MI.15772	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	37	13	T	A	Acc/Gcc	-5,47	0	0	benign	0,01	neutral	0,29	neutral	2	neutral	0,03	neutral	-1,12	low_impact	1,02	neutral	0,86	neutral	1	neutral	-0,26	0,81	0,55	0,6	neutral	0,16	neutral	0,49	neutral	0,47	neutral	0,46	1	neutral	0,7	deleterious	0,64	neutral	-6	neutral	0,1	medium_impact	1,03	medium_impact	-0,01	medium_impact	-0,28	0,5	0,8	14,29	11,87	N	0,3	N	0,12	polymorphism	1	0,03	rs199688733	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10506	10506	A	T	MI.15773	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	37	13	T	S	Acc/Tcc	-5,47	0	0	benign	0,02	neutral	0,5	neutral	1,97	neutral	-0,41	neutral	-0,99	neutral_impact	0,3	neutral	0,85	neutral	0,98	neutral	-0,09	1,8	0,4	0,5	neutral	0,19	neutral	0,42	neutral	0,34	neutral	0,45	1	neutral	0,48	deleterious	0,74	neutral	-6	neutral	0,1	medium_impact	0,75	medium_impact	0,21	medium_impact	-0,89	0,49	0,8	14,29	11,87	N	0,34	N	0,06	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10507	10507	C	T	MI.15774	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	38	13	T	I	aCc/aTc	-5,24	0	0	benign	0,01	neutral	0,81	neutral	2,03	neutral	0,35	neutral	-0,56	neutral_impact	-0,24	neutral	0,84	neutral	0,99	neutral	-0,49	0,24	0,58	0,65	neutral	0,11	disease	0,54	neutral	0,32	neutral	0,43	1	neutral	0,16	deleterious	0,9	neutral	-6	neutral	0,1	medium_impact	1,03	medium_impact	0,56	low_impact	-1,34	0,56	0,8	14,29	11,87	N	0,26	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10507	10507	C	G	MI.15775	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	38	13	T	S	aCc/aGc	-5,24	0	0	benign	0,02	neutral	0,5	neutral	1,97	neutral	-0,41	neutral	-0,99	neutral_impact	0,3	neutral	0,85	neutral	0,98	deleterious	0,13	3,95	0,4	0,5	neutral	0,19	neutral	0,42	neutral	0,34	neutral	0,45	1	neutral	0,48	deleterious	0,74	neutral	-6	neutral	0,1	medium_impact	0,75	medium_impact	0,21	medium_impact	-0,89	0,49	0,8	14,29	11,87	N	0,36	N	0,06	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10507	10507	C	A	MI.15776	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	38	13	T	N	aCc/aAc	-5,24	0	0	benign	0,38	neutral	0,15	neutral	1,89	neutral	-2,98	neutral	-2,38	medium_impact	2,96	neutral	0,85	neutral	0,53	deleterious	3,15	22,6	0,57	0,65	neutral	0,42	disease	0,72	disease	0,59	disease	0,73	5	neutral	0,82	neutral	0,39	neutral	-3	neutral	0,32	medium_impact	-0,61	medium_impact	-0,21	medium_impact	1,34	0,72	0,85	14,29	11,87	N	0,35	N	0,59	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10509	10509	A	C	MI.15777	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	40	14	I	L	Atc/Ctc	-10,78	0	0	benign	0,12	neutral	1	neutral	1,82	neutral	-0,77	neutral	-0,13	neutral_impact	-0,35	neutral	0,77	neutral	0,97	neutral	-0,95	0,02	0,36	0,5	neutral	0,17	neutral	0,33	neutral	0,29	neutral	0,45	1	neutral	0,11	deleterious	0,94	neutral	-6	neutral	0,11	medium_impact	-0,01	high_impact	1,88	low_impact	-1,43	0,68	0,85	31,63	17,67	N	0,27	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10509	10509	A	T	MI.15778	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	40	14	I	F	Atc/Ttc	-10,78	0	0	possibly_damaging	0,72	neutral	0,66	neutral	1,59	deleterious	-3,07	neutral	-1,64	neutral_impact	0,5	neutral	0,76	neutral	0,93	deleterious	2,19	17,43	0,42	0,55	neutral	0,23	disease	0,71	neutral	0,43	disease	0,58	2	neutral	0,66	deleterious	0,47	neutral	-3	neutral	0,43	low_impact	-1,18	medium_impact	0,37	medium_impact	-0,72	0,69	0,85	31,63	17,67	N	0,29	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10509	10509	A	G	MI.15779	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	40	14	I	V	Atc/Gtc	-10,78	0	0	benign	0,29	neutral	0,41	neutral	1,67	neutral	-1,83	neutral	-0,25	neutral_impact	0,22	neutral	0,84	neutral	0,99	neutral	-0,19	1,15	0,6	0,65	neutral	0,11	neutral	0,47	neutral	0,41	neutral	0,44	1	neutral	0,51	deleterious	0,56	neutral	-6	neutral	0,14	medium_impact	-0,45	medium_impact	0,12	medium_impact	-0,95	0,48	0,8	31,63	17,67	N	0,3	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8429	8429	C	G	MI.1578	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	64	22	L	V	Ctc/Gtc	-7,04	0	0,01	probably_damaging	0,97	neutral	0,55	neutral	0,69	deleterious	-3,33	neutral	-0,25	medium_impact	1,99	neutral	1	neutral	0,75	deleterious	3,23	22,8	0,47385093	0,85	neutral	0,24	neutral	0,14	neutral	0,29	neutral	0,12	8	neutral	0,97	neutral	0,29	deleterious	1	deleterious	0,69	low_impact	-2,19	medium_impact	0,34	medium_impact	0,61	0,67	0,85	14,71	8,52	N	0,39	N	0,3	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10510	10510	T	C	MI.15780	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	41	14	I	T	aTc/aCc	-3,17	0	0	benign	0,04	neutral	0,17	neutral	1,59	deleterious	-3,12	neutral	-1,92	low_impact	1,93	neutral	0,86	neutral	0,97	deleterious	0,14	4,02	0,67	0,7	neutral	0,44	disease	0,57	neutral	0,46	neutral	0,49	0	neutral	0,82	deleterious	0,57	neutral	-6	neutral	0,16	medium_impact	0,46	medium_impact	-0,17	medium_impact	0,48	0,65	0,8	31,63	17,67	N	0,44	N	0,53	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10510	10510	T	A	MI.15781	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	41	14	I	N	aTc/aAc	-3,17	0	0	possibly_damaging	0,72	neutral	0,1	neutral	1,54	deleterious	-5,09	deleterious	-3,99	medium_impact	3,18	neutral	0,73	neutral	0,4	deleterious	3,95	23,6	0,4	0,5	disease	0,71	disease	0,84	disease	0,62	disease	0,81	6	neutral	0,92	neutral	0,19	NA	0	deleterious	0,56	low_impact	-1,18	medium_impact	-0,32	medium_impact	1,53	0,65	0,8	31,63	17,67	N	0,35	N	0,84	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10510	10510	T	G	MI.15782	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	41	14	I	S	aTc/aGc	-3,17	0	0	benign	0,4	neutral	0,28	neutral	1,63	neutral	-2,4	deleterious	-2,84	low_impact	1,28	neutral	0,69	neutral	0,57	deleterious	3,75	23,3	0,41	0,5	disease	0,55	disease	0,8	neutral	0,45	disease	0,71	4	neutral	0,67	neutral	0,44	neutral	-6	neutral	0,34	medium_impact	-0,64	medium_impact	-0,02	medium_impact	-0,07	0,57	0,8	31,63	17,67	N	0,3	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10511	10511	C	G	MI.15783	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	42	14	I	M	atC/atG	1,44	0	0	benign	0,08	neutral	0,34	neutral	1,59	deleterious	-3,09	neutral	-0,02	neutral_impact	0,65	neutral	0,82	neutral	0,98	deleterious	0,1	3,6	0,45	0,55	neutral	0,27	disease	0,51	neutral	0,35	neutral	0,46	1	neutral	0,62	deleterious	0,63	neutral	-6	neutral	0,14	medium_impact	0,17	medium_impact	0,05	medium_impact	-0,59	0,77	0,85	31,63	17,67	N	0,43	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10511	10511	C	A	MI.15784	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	42	14	I	M	atC/atA	1,44	0	0	benign	0,08	neutral	0,34	neutral	1,59	deleterious	-3,09	neutral	-0,02	neutral_impact	0,65	neutral	0,82	neutral	0,98	deleterious	0,51	7,54	0,45	0,55	neutral	0,27	disease	0,51	neutral	0,35	neutral	0,46	1	neutral	0,62	deleterious	0,63	neutral	-6	neutral	0,14	medium_impact	0,17	medium_impact	0,05	medium_impact	-0,59	0,77	0,85	31,63	17,67	N	0,42	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10512	10512	T	G	MI.15785	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	43	15	S	A	Tca/Gca	-7,78	0	0	benign	0,3	neutral	0,51	neutral	1,98	neutral	-0,19	neutral	-1,25	neutral_impact	0,6	neutral	0,77	neutral	0,96	deleterious	1,95	15,92	0,57	0,65	neutral	0,23	disease	0,55	neutral	0,4	neutral	0,45	1	neutral	0,39	deleterious	0,61	neutral	-6	deleterious	0,72	medium_impact	-0,47	medium_impact	0,22	medium_impact	-0,64	0,72	0,85	48,98	8,72	N	0,31	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10512	10512	T	C	MI.15786	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	43	15	S	P	Tca/Cca	-7,78	0	0	probably_damaging	0,99	neutral	0,2	neutral	1,81	deleterious	-3,7	deleterious	-4,04	medium_impact	3,32	neutral	0,7	damaging	0,13	deleterious	3,73	23,3	0,25	0,45	disease	0,64	disease	0,95	disease	0,69	disease	0,85	7	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,88	low_impact	-2,63	medium_impact	-0,12	medium_impact	1,65	0,65	0,8	48,98	8,72	N	0,31	N	0,87	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10512	10512	T	A	MI.15787	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	43	15	S	T	Tca/Aca	-7,78	0	0	probably_damaging	0,92	neutral	0,39	neutral	1,83	neutral	-2,38	neutral	-2,19	medium_impact	2,23	neutral	0,74	neutral	0,39	deleterious	3,48	23,1	0,49	0,55	neutral	0,42	disease	0,68	neutral	0,45	disease	0,52	0	neutral	0,93	neutral	0,24	deleterious	1	deleterious	0,76	low_impact	-1,78	medium_impact	0,1	medium_impact	0,73	0,72	0,85	48,98	8,72	N	0,33	N	0,57	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10513	10513	C	G	MI.15788	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	44	15	S	W	tCa/tGa	0,29	0,06	0	probably_damaging	1	neutral	0,19	neutral	1,79	deleterious	-6,47	deleterious	-6	high_impact	3,66	neutral	0,68	damaging	0,1	deleterious	4,14	23,8	0,2	0,45	disease	0,93	disease	0,95	disease	0,67	disease	0,84	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,14	medium_impact	1,93	0,48	0,8	48,98	8,72	N	0,31	N	0,97	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10513	10513	C	T	MI.15789	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	44	15	S	L	tCa/tTa	0,29	0,06	0	probably_damaging	0,94	neutral	0,65	neutral	1,82	deleterious	-3,14	deleterious	-4,73	medium_impact	2,28	neutral	0,69	damaging	0,15	deleterious	4,47	24,2	0,34	0,5	disease	0,67	disease	0,92	disease	0,54	disease	0,77	5	neutral	0,93	neutral	0,36	deleterious	1	deleterious	0,84	low_impact	-1,9	medium_impact	0,36	medium_impact	0,77	0,81	0,85	48,98	8,72	N	0,25	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8429	8429	C	A	MI.1579	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	64	22	L	I	Ctc/Atc	-7,04	0	0,01	probably_damaging	0,97	neutral	1	neutral	0,76	neutral	-2,75	neutral	0,56	neutral_impact	0,4	neutral	0,97	neutral	0,92	neutral	1,57	13,67	0,45672233	0,85	neutral	0,1	neutral	0,05	neutral	0,19	neutral	0,04	9	neutral	0,97	deleterious	0,52	neutral	-2	deleterious	0,66	low_impact	-2,19	high_impact	1,98	medium_impact	-0,76	0,6	0,85	14,71	8,52	N	0,39	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10515	10515	C	A	MI.15790	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	46	16	L	I	Ctt/Att	-8,01	0	0	possibly_damaging	0,9	neutral	0,46	neutral	1,82	neutral	-0,93	neutral	-1,66	low_impact	1,68	neutral	0,74	neutral	0,49	deleterious	2,82	21,5	0,51	0,6	neutral	0,4	disease	0,58	neutral	0,39	neutral	0,49	0	neutral	0,89	neutral	0,28	neutral	-3	deleterious	0,73	low_impact	-1,68	medium_impact	0,17	medium_impact	0,27	0,64	0,8	48,98	9,49	N	0,36	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10515	10515	C	G	MI.15791	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	46	16	L	V	Ctt/Gtt	-8,01	0	0	possibly_damaging	0,9	neutral	0,49	neutral	1,81	neutral	-1,06	deleterious	-2,62	medium_impact	2,08	neutral	0,77	neutral	0,29	deleterious	3,19	22,7	0,51	0,6	neutral	0,4	disease	0,71	neutral	0,46	disease	0,54	1	neutral	0,89	neutral	0,3	NA	0	deleterious	0,75	low_impact	-1,68	medium_impact	0,2	medium_impact	0,61	0,61	0,8	48,98	9,49	N	0,22	N	0,65	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10515	10515	C	T	MI.15792	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	46	16	L	F	Ctt/Ttt	-8,01	0	0	possibly_damaging	0,5	neutral	0,61	neutral	1,7	neutral	-2,08	neutral	-2,45	low_impact	1,06	neutral	0,78	neutral	0,95	neutral	0,94	10,29	0,53	0,6	neutral	0,3	disease	0,66	neutral	0,47	neutral	0,49	0	neutral	0,43	deleterious	0,56	neutral	-3	deleterious	0,73	medium_impact	-0,8	medium_impact	0,32	medium_impact	-0,25	0,64	0,8	48,98	9,49	N	0,24	N	0,33	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10516	10516	T	C	MI.15793	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	47	16	L	P	cTt/cCt	-1,78	0	0	probably_damaging	1	neutral	0,09	neutral	1,61	deleterious	-5,11	deleterious	-6,41	high_impact	3,96	neutral	0,64	damaging	0,09	deleterious	3,72	23,3	0,21	0,45	disease	0,8	disease	0,93	disease	0,75	disease	0,88	8	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,35	high_impact	2,18	0,56	0,8	48,98	9,49	N	0,33	N	0,95	polymorphism	0,83	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10516	10516	T	G	MI.15794	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	47	16	L	R	cTt/cGt	-1,78	0	0	probably_damaging	0,99	neutral	0,16	neutral	1,62	deleterious	-4,55	deleterious	-5,43	high_impact	3,96	neutral	0,7	damaging	0,09	deleterious	4,02	23,6	0,21	0,45	disease	0,73	disease	0,93	disease	0,75	disease	0,88	8	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-2,63	medium_impact	-0,19	high_impact	2,18	0,62	0,8	48,98	9,49	N	0,34	N	0,98	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10516	10516	T	A	MI.15795	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	47	16	L	H	cTt/cAt	-1,78	0	0	probably_damaging	1	neutral	0,26	neutral	1,61	deleterious	-5,08	deleterious	-5,98	high_impact	3,96	neutral	0,74	damaging	0,12	deleterious	4,04	23,7	0,24	0,45	disease	0,77	disease	0,89	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	-0,04	high_impact	2,18	0,51	0,8	48,98	9,49	N	0,31	N	0,97	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10518	10518	C	A	MI.15796	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	49	17	L	M	Cta/Ata	-14	0	0	probably_damaging	0,95	neutral	0,31	neutral	1,82	neutral	-1,58	neutral	-0,92	low_impact	0,93	neutral	0,79	neutral	0,97	deleterious	1,97	16,04	0,42	0,55	neutral	0,27	neutral	0,14	neutral	0,31	neutral	0,28	4	neutral	0,96	neutral	0,18	neutral	-2	deleterious	0,64	low_impact	-1,97	medium_impact	0,02	medium_impact	-0,36	0,65	0,8	20,41	17,97	N	0,42	N	0,05	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10518	10518	C	G	MI.15797	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	49	17	L	V	Cta/Gta	-14	0	0	benign	0,12	neutral	0,57	neutral	1,85	neutral	-1,15	neutral	-1,52	low_impact	0,94	neutral	0,8	neutral	0,96	deleterious	2	16,18	0,48	0,55	neutral	0,17	neutral	0,46	neutral	0,37	neutral	0,45	1	neutral	0,33	deleterious	0,73	neutral	-6	deleterious	0,65	medium_impact	-0,01	medium_impact	0,28	medium_impact	-0,35	0,57	0,8	20,41	17,97	N	0,32	N	0,15	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10519	10519	T	C	MI.15798	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	50	17	L	P	cTa/cCa	-1,55	0	0	probably_damaging	0,96	neutral	0,19	neutral	1,73	deleterious	-4,52	deleterious	-5,4	high_impact	3,64	neutral	0,66	damaging	0,21	deleterious	3,69	23,3	0,3	0,45	disease	0,57	disease	0,9	disease	0,73	disease	0,83	7	neutral	0,98	neutral	0,12	deleterious	2	deleterious	0,83	low_impact	-2,07	medium_impact	-0,14	medium_impact	1,91	0,56	0,8	20,41	17,97	N	0,33	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10519	10519	T	A	MI.15799	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	50	17	L	Q	cTa/cAa	-1,55	0	0	probably_damaging	0,96	neutral	0,28	neutral	1,74	deleterious	-4,13	deleterious	-4,55	high_impact	3,64	neutral	0,8	damaging	0,19	deleterious	3,82	23,4	0,3	0,45	neutral	0,5	disease	0,72	disease	0,61	disease	0,73	5	neutral	0,97	neutral	0,16	deleterious	2	deleterious	0,73	low_impact	-2,07	medium_impact	-0,02	medium_impact	1,91	0,56	0,8	20,41	17,97	N	0,32	N	0,84	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8600	8600	T	C	MI.158	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	74	25	L	P	cTa/cCa	-2,19	0	0	probably_damaging	1	deleterious	0,04	neutral	4,25	neutral	-1,12	deleterious	-3,88	medium_impact	2,65	neutral	0,77	neutral	0,51	deleterious	3,63	23,2	0,19	0,65	disease	0,88	disease	0,69	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,84	low_impact	-3,6	medium_impact	-0,49	medium_impact	1,17	0,61	0,9	10,18	13,06	N	0,28	N	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8430	8430	T	A	MI.1580	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	65	22	L	H	cTc/cAc	-3,11	0	0	probably_damaging	1	deleterious	0,03	neutral	0,56	deleterious	-7,74	deleterious	-4,42	medium_impact	2,44	neutral	0,99	neutral	0,74	deleterious	3,99	23,6	0,26709301	0,85	disease	0,87	neutral	0,42	neutral	0,4	neutral	0,26	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,81	low_impact	-3,6	medium_impact	-0,56	medium_impact	0,99	0,59	0,85	14,71	8,52	P	0,54	P	0,62	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10519	10519	T	G	MI.15800	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	50	17	L	R	cTa/cGa	-1,55	0	0	probably_damaging	0,95	neutral	0,39	neutral	1,74	deleterious	-3,95	deleterious	-4,76	high_impact	3,64	neutral	0,72	damaging	0,12	deleterious	3,98	23,6	0,28	0,45	neutral	0,48	disease	0,88	disease	0,72	disease	0,81	6	neutral	0,95	neutral	0,22	deleterious	2	deleterious	0,8	low_impact	-1,97	medium_impact	0,1	medium_impact	1,91	0,61	0,8	20,41	17,97	N	0,31	N	0,94	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10521	10521	G	T	MI.15801	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	52	18	G	W	Gga/Tga	-2,94	0	0	probably_damaging	1	neutral	0,19	neutral	1,54	deleterious	-7,27	deleterious	-7,9	high_impact	4,41	damaging	0,57	damaging	0,04	deleterious	4,22	23,9	0,18	0,45	disease	0,92	disease	0,95	disease	0,73	disease	0,83	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,14	high_impact	2,56	0,38	0,8	53,06	11,91	N	0,41	N	0,99	disease_causing	0,79	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10521	10521	G	C	MI.15802	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	52	18	G	R	Gga/Cga	-2,94	0	0	probably_damaging	1	neutral	0,35	neutral	1,56	deleterious	-4,69	deleterious	-7,86	high_impact	4,41	damaging	0,54	damaging	0,04	deleterious	3,71	23,3	0,21	0,45	disease	0,73	disease	0,95	disease	0,79	disease	0,89	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0,06	high_impact	2,56	0,78	0,85	53,06	11,91	N	0,51	P	0,99	disease_causing	0,69	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10522	10522	G	C	MI.15803	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	53	18	G	A	gGa/gCa	7,21	1	0	probably_damaging	1	neutral	0,51	neutral	1,63	neutral	-2,92	deleterious	-5,9	medium_impact	3,02	neutral	0,67	damaging	0,14	deleterious	2,94	22	0,31	0,5	neutral	0,38	disease	0,83	disease	0,55	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,79	low_impact	-3,55	medium_impact	0,22	medium_impact	1,39	0,75	0,85	53,06	11,91	N	0,47	N	0,98	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10522	10522	G	A	MI.15804	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	53	18	G	E	gGa/gAa	7,21	1	0	probably_damaging	1	neutral	0,27	neutral	1,56	deleterious	-4,44	deleterious	-7,81	high_impact	4,41	neutral	0,62	damaging	0,06	deleterious	3,7	23,3	0,17	0,45	disease	0,73	disease	0,94	disease	0,78	disease	0,85	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,03	high_impact	2,56	0,62	0,8	53,06	11,91	P	0,7	P	0,99	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10522	10522	G	T	MI.15805	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	53	18	G	V	gGa/gTa	7,21	1	0	probably_damaging	1	neutral	0,5	neutral	1,67	deleterious	-3,23	deleterious	-8,87	medium_impact	2,45	neutral	0,61	damaging	0,04	deleterious	3,57	23,1	0,2	0,45	neutral	0,26	disease	0,94	disease	0,59	disease	0,78	6	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,8	low_impact	-3,55	medium_impact	0,21	medium_impact	0,92	0,57	0,8	53,06	11,91	N	0,42	N	1	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10524	10524	A	G	MI.15806	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	55	19	M	V	Ata/Gta	-15,39	0	0	benign	0,01	neutral	0,45	neutral	2,25	neutral	2,14	neutral	-0,71	neutral_impact	-0,02	neutral	0,81	neutral	0,97	neutral	-0,53	0,19	0,74	0,8	neutral	0,13	disease	0,58	neutral	0,41	neutral	0,45	1	neutral	0,54	deleterious	0,72	neutral	-6	neutral	0,15	medium_impact	1,03	medium_impact	0,16	low_impact	-1,16	0,5	0,8	34,69	22,61	N	0,3	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10524	10524	A	T	MI.15807	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	55	19	M	L	Ata/Tta	-15,39	0	0	benign	0,01	neutral	1	neutral	2,35	neutral	2,58	neutral	-0,23	neutral_impact	-1,21	neutral	0,79	neutral	0,99	neutral	-1,35	0	0,65	0,7	neutral	0,22	neutral	0,33	neutral	0,34	neutral	0,43	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,12	medium_impact	1,03	high_impact	1,88	low_impact	-2,15	0,54	0,8	34,69	22,61	N	0,34	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10524	10524	A	C	MI.15808	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	55	19	M	L	Ata/Cta	-15,39	0	0	benign	0,01	neutral	1	neutral	2,35	neutral	2,58	neutral	-0,23	neutral_impact	-1,21	neutral	0,79	neutral	0,99	neutral	-1,46	0	0,65	0,7	neutral	0,22	neutral	0,33	neutral	0,34	neutral	0,43	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,12	medium_impact	1,03	high_impact	1,88	low_impact	-2,15	0,54	0,8	34,69	22,61	N	0,33	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10525	10525	T	A	MI.15809	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	56	19	M	K	aTa/aAa	-1,55	0	0	benign	0,34	neutral	0,26	neutral	1,93	neutral	-2,45	deleterious	-3,42	medium_impact	2,6	neutral	0,68	neutral	0,45	deleterious	3,7	23,3	0,35	0,5	neutral	0,34	disease	0,81	disease	0,68	disease	0,8	6	neutral	0,69	neutral	0,46	neutral	-3	deleterious	0,53	medium_impact	-0,54	medium_impact	-0,04	medium_impact	1,04	0,58	0,8	34,69	22,61	N	0,35	N	0,72	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8430	8430	T	C	MI.1581	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	65	22	L	P	cTc/cCc	-3,11	0	0	probably_damaging	1	deleterious	0,01	neutral	0,56	deleterious	-7,36	deleterious	-5	medium_impact	2,79	neutral	0,99	neutral	0,39	deleterious	3,76	23,3	0,1708065	0,85	disease	0,83	disease	0,54	disease	0,64	disease	0,61	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,29	0,54	0,85	14,71	8,52	N	0,51	P	0,74	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10525	10525	T	C	MI.15810	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	56	19	M	T	aTa/aCa	-1,55	0	0	benign	0,02	neutral	0,31	neutral	1,99	neutral	-0,25	neutral	-1,55	neutral_impact	0,31	neutral	0,83	neutral	0,99	neutral	-0,15	1,41	0,66	0,7	neutral	0,12	neutral	0,43	neutral	0,44	neutral	0,45	1	neutral	0,68	deleterious	0,65	neutral	-6	neutral	0,29	medium_impact	0,75	medium_impact	0,02	medium_impact	-0,88	0,41	0,8	34,69	22,61	N	0,35	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10526	10526	A	T	MI.15811	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	57	19	M	I	atA/atT	2,83	0,12	0	benign	0,01	neutral	0,44	neutral	2,23	neutral	2,04	neutral	-0,64	neutral_impact	0,66	neutral	0,78	neutral	0,93	deleterious	0,2	4,69	0,56	0,6	neutral	0,14	disease	0,65	neutral	0,39	disease	0,53	1	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,16	medium_impact	1,03	medium_impact	0,15	medium_impact	-0,59	0,59	0,8	34,69	22,61	N	0,36	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10526	10526	A	C	MI.15812	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	57	19	M	I	atA/atC	2,83	0,12	0	benign	0,01	neutral	0,44	neutral	2,23	neutral	2,04	neutral	-0,64	neutral_impact	0,66	neutral	0,78	neutral	0,93	deleterious	0,15	4,16	0,56	0,6	neutral	0,14	disease	0,65	neutral	0,39	disease	0,53	1	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,16	medium_impact	1,03	medium_impact	0,15	medium_impact	-0,59	0,59	0,8	34,69	22,61	N	0,36	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10527	10527	C	G	MI.15813	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	58	20	L	V	Cta/Gta	-5,93	0	0,01	possibly_damaging	0,9	neutral	0,61	neutral	1,62	neutral	-2,18	neutral	-2,35	low_impact	1,54	neutral	0,78	neutral	0,32	deleterious	2,05	16,51	0,69	0,75	neutral	0,12	neutral	0,49	neutral	0,29	neutral	0,43	1	neutral	0,88	neutral	0,36	neutral	-3	deleterious	0,6	low_impact	-1,68	medium_impact	0,32	medium_impact	0,15	0,72	0,85	51,02	8,89	N	0,2	N	0,48	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10527	10527	C	A	MI.15814	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	58	20	L	M	Cta/Ata	-5,93	0	0,01	probably_damaging	0,99	neutral	0,25	neutral	1,58	neutral	-2,71	neutral	-0,84	medium_impact	2,25	neutral	0,8	neutral	0,87	deleterious	2,05	16,51	0,44	0,55	neutral	0,4	neutral	0,34	neutral	0,32	neutral	0,46	1	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,68	low_impact	-2,63	medium_impact	-0,06	medium_impact	0,75	0,7	0,85	51,02	8,89	N	0,42	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10528	10528	T	A	MI.15815	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	59	20	L	Q	cTa/cAa	-1,78	0	0	probably_damaging	0,99	neutral	0,3	neutral	1,52	deleterious	-4,47	deleterious	-4,82	high_impact	3,88	neutral	0,69	damaging	0,12	deleterious	4,14	23,8	0,29	0,45	disease	0,55	disease	0,73	neutral	0,48	disease	0,52	0	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,77	low_impact	-2,63	medium_impact	0,01	high_impact	2,11	0,69	0,85	51,02	8,89	N	0,36	N	0,95	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10528	10528	T	C	MI.15816	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	59	20	L	P	cTa/cCa	-1,78	0	0	probably_damaging	0,99	neutral	0,19	neutral	1,5	deleterious	-5,5	deleterious	-6	high_impact	3,88	damaging	0,57	damaging	0,07	deleterious	3,74	23,3	0,24	0,45	disease	0,63	disease	0,89	disease	0,63	disease	0,79	6	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-2,63	medium_impact	-0,14	high_impact	2,11	0,46	0,8	51,02	8,89	N	0,3	N	0,95	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10528	10528	T	G	MI.15817	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	59	20	L	R	cTa/cGa	-1,78	0	0	probably_damaging	0,98	neutral	0,43	neutral	1,51	deleterious	-4,93	deleterious	-5	high_impact	3,88	neutral	0,65	damaging	0,07	deleterious	3,98	23,6	0,3	0,45	disease	0,54	disease	0,87	disease	0,62	disease	0,79	6	deleterious	0,98	neutral	0,23	deleterious	2	deleterious	0,81	low_impact	-2,35	medium_impact	0,14	high_impact	2,11	0,69	0,85	51,02	8,89	N	0,27	N	0,98	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10530	10530	G	T	MI.15818	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	61	21	V	L	Gta/Tta	-5,24	0	0	benign	0,03	neutral	0,67	neutral	2,12	neutral	0,26	neutral	0,15	neutral_impact	-0,08	neutral	0,71	neutral	0,97	deleterious	0,08	3,41	0,75	0,8	neutral	0,11	neutral	0,27	neutral	0,2	neutral	0,42	2	neutral	0,29	deleterious	0,82	neutral	-6	neutral	0,12	medium_impact	0,58	medium_impact	0,38	low_impact	-1,21	0,75	0,85	26,53	16,25	N	0,36	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10530	10530	G	C	MI.15819	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	61	21	V	L	Gta/Cta	-5,24	0	0	benign	0,03	neutral	0,67	neutral	2,12	neutral	0,26	neutral	0,15	neutral_impact	-0,08	neutral	0,71	neutral	0,97	neutral	-0,08	1,89	0,75	0,8	neutral	0,11	neutral	0,27	neutral	0,2	neutral	0,42	2	neutral	0,29	deleterious	0,82	neutral	-6	neutral	0,12	medium_impact	0,58	medium_impact	0,38	low_impact	-1,21	0,75	0,85	26,53	16,25	N	0,36	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8430	8430	T	G	MI.1582	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	65	22	L	R	cTc/cGc	-3,11	0	0	probably_damaging	1	deleterious	0,02	neutral	0,56	deleterious	-7,07	deleterious	-4,58	medium_impact	2,79	neutral	1	neutral	0,49	deleterious	4,05	23,7	0,16376862	0,85	disease	0,79	disease	0,57	disease	0,63	disease	0,61	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,85	low_impact	-3,6	medium_impact	-0,66	medium_impact	1,29	0,62	0,85	14,71	8,52	N	0,53	P	0,68	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10530	10530	G	A	MI.15820	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	61	21	V	M	Gta/Ata	-5,24	0	0	benign	0,02	neutral	0,26	neutral	1,95	neutral	-1,41	neutral	0,68	neutral_impact	-0,8	neutral	0,8	neutral	0,98	neutral	-0,25	0,88	0,65	0,7	neutral	0,11	neutral	0,2	neutral	0,22	neutral	0,35	3	neutral	0,73	deleterious	0,62	neutral	-6	neutral	0,12	medium_impact	0,75	medium_impact	-0,04	low_impact	-1,81	0,81	0,85	26,53	16,25	N	0,36	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10531	10531	T	G	MI.15821	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	62	21	V	G	gTa/gGa	-0,86	0	0	benign	0,34	neutral	0,22	neutral	1,88	deleterious	-3,13	deleterious	-5,18	low_impact	1,71	neutral	0,75	neutral	0,47	deleterious	1,85	15,26	0,42	0,55	neutral	0,42	disease	0,6	neutral	0,47	disease	0,54	1	neutral	0,74	neutral	0,44	neutral	-6	neutral	0,41	medium_impact	-0,54	medium_impact	-0,1	medium_impact	0,3	0,63	0,8	26,53	16,25	N	0,37	N	0,68	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10531	10531	T	C	MI.15822	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	62	21	V	A	gTa/gCa	-0,86	0	0	benign	0,12	neutral	0,35	neutral	1,95	neutral	-1,39	deleterious	-2,65	low_impact	1,12	neutral	0,75	neutral	0,76	neutral	1,52	13,39	0,74	0,75	neutral	0,21	neutral	0,32	neutral	0,37	neutral	0,46	1	neutral	0,6	deleterious	0,62	neutral	-6	neutral	0,22	medium_impact	-0,01	medium_impact	0,06	medium_impact	-0,2	0,48	0,8	26,53	16,25	N	0,44	N	0,33	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10531	10531	T	A	MI.15823	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	62	21	V	E	gTa/gAa	-0,86	0	0	benign	0,34	neutral	0,15	neutral	1,88	deleterious	-3,15	deleterious	-4,2	medium_impact	2,52	neutral	0,72	neutral	0,45	deleterious	2,99	22,2	0,32	0,5	neutral	0,42	disease	0,74	disease	0,52	disease	0,64	3	neutral	0,82	neutral	0,41	neutral	-3	deleterious	0,58	medium_impact	-0,54	medium_impact	-0,21	medium_impact	0,97	0,53	0,8	26,53	16,25	N	0,39	N	0,62	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10533	10533	T	A	MI.15824	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	64	22	Y	N	Tat/Aat	-5,93	0	0	probably_damaging	1	neutral	0,36	neutral	2,07	neutral	1,59	deleterious	-7,94	neutral_impact	0,62	neutral	0,76	neutral	0,8	deleterious	2,75	21,1	0,58	0,65	neutral	0,14	disease	0,66	neutral	0,37	neutral	0,44	1	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,7	low_impact	-3,55	medium_impact	0,07	medium_impact	-0,62	0,4	0,8	25,51	12,02	N	0,3	N	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10533	10533	T	C	MI.15825	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	64	22	Y	H	Tat/Cat	-5,93	0	0	probably_damaging	1	neutral	0,73	neutral	2,03	neutral	0,39	deleterious	-4,61	low_impact	1,2	neutral	0,71	neutral	0,88	deleterious	0,68	8,68	0,76	0,8	neutral	0,21	neutral	0,22	neutral	0,26	neutral	0,39	2	deleterious	1	neutral	0,37	neutral	-2	deleterious	0,68	low_impact	-3,55	medium_impact	0,45	medium_impact	-0,13	0,44	0,8	25,51	12,02	N	0,31	N	0,79	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10533	10533	T	G	MI.15826	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	64	22	Y	D	Tat/Gat	-5,93	0	0	probably_damaging	1	neutral	0,19	neutral	1,98	neutral	0,28	deleterious	-8,62	medium_impact	3,29	neutral	0,8	neutral	0,39	deleterious	3,81	23,4	0,54	0,6	neutral	0,32	disease	0,88	disease	0,62	disease	0,8	6	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,78	low_impact	-3,55	medium_impact	-0,14	medium_impact	1,62	0,44	0,8	25,51	12,02	N	0,39	N	0,9	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10534	10534	A	G	MI.15827	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	65	22	Y	C	tAt/tGt	2,14	0,96	0	probably_damaging	1	neutral	0,17	neutral	1,93	neutral	-2,57	deleterious	-7,66	medium_impact	2,94	neutral	0,66	neutral	0,37	deleterious	3,37	22,9	0,56	0,6	disease	0,66	disease	0,79	disease	0,63	disease	0,76	5	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,79	low_impact	-3,55	medium_impact	-0,17	medium_impact	1,33	0,15	0,8	25,51	12,02	N	0,46	N	0,81	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10534	10534	A	T	MI.15828	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	65	22	Y	F	tAt/tTt	2,14	0,96	0	probably_damaging	1	neutral	0,72	neutral	2,01	neutral	-0,25	neutral	-1,87	neutral_impact	0,07	neutral	0,84	neutral	0,96	neutral	1,6	13,85	0,45	0,55	neutral	0,2	disease	0,52	neutral	0,35	neutral	0,47	1	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,71	low_impact	-3,55	medium_impact	0,44	low_impact	-1,08	0,43	0,8	25,51	12,02	N	0,33	N	0,32	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10534	10534	A	C	MI.15829	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	65	22	Y	S	tAt/tCt	2,14	0,96	0	probably_damaging	1	neutral	0,45	neutral	2,04	neutral	1,17	deleterious	-7,63	low_impact	1,84	neutral	0,8	neutral	0,57	deleterious	3,52	23,1	0,45	0,55	neutral	0,25	disease	0,72	neutral	0,44	disease	0,52	0	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,73	low_impact	-3,55	medium_impact	0,16	medium_impact	0,4	0,49	0,8	25,51	12,02	N	0,39	N	0,86	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8432	8432	A	G	MI.1583	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	67	23	I	V	Atc/Gtc	-5,89	0	0	benign	0	neutral	0,37	neutral	2,01	neutral	-1,4	neutral	-0,37	low_impact	1,42	neutral	1	neutral	0,96	neutral	-0,3	0,65	0,66698427	0,85	neutral	0,13	neutral	0,1	neutral	0,42	neutral	0,05	9	neutral	0,63	deleterious	0,69	neutral	-6	neutral	0,13	high_impact	2,09	medium_impact	0,16	medium_impact	0,12	0,66	0,85	1,47	7,72	N	0,45	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10536	10536	C	A	MI.15830	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	67	23	R	S	Cgc/Agc	-2,24	0	0	probably_damaging	0,96	neutral	0,43	neutral	1,63	deleterious	-4,91	deleterious	-5,87	high_impact	3,55	damaging	0,53	damaging	0,02	deleterious	4,54	24,3	0,41	0,5	disease	0,82	disease	0,88	disease	0,73	disease	0,81	6	neutral	0,96	neutral	0,24	deleterious	2	deleterious	0,88	low_impact	-2,07	medium_impact	0,14	medium_impact	1,84	0,4	0,8	54,08	11,58	N	0,28	N	0,87	disease_causing	0,64	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10536	10536	C	T	MI.15831	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	67	23	R	C	Cgc/Tgc	-2,24	0	0	probably_damaging	0,99	neutral	0,18	neutral	1,49	deleterious	-7,88	deleterious	-7,86	high_impact	4,59	damaging	0,51	damaging	0,01	deleterious	4,84	24,8	0,34	0,5	disease	0,95	disease	0,89	disease	0,78	disease	0,88	8	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-2,63	medium_impact	-0,16	high_impact	2,71	0,69	0,85	54,08	11,58	N	0,47	N	1	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10536	10536	C	G	MI.15832	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	67	23	R	G	Cgc/Ggc	-2,24	0	0	probably_damaging	0,97	neutral	0,33	neutral	1,51	deleterious	-5,71	deleterious	-6,87	high_impact	4,04	damaging	0,56	damaging	0,05	deleterious	4,03	23,6	0,37	0,5	disease	0,84	disease	0,86	disease	0,74	disease	0,81	6	neutral	0,97	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-2,19	medium_impact	0,04	high_impact	2,25	0,36	0,8	54,08	11,58	N	0,32	N	0,93	disease_causing	0,63	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10537	10537	G	T	MI.15833	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	68	23	R	L	cGc/cTc	4,44	0,99	0	probably_damaging	0,97	neutral	0,69	neutral	1,51	deleterious	-5,31	deleterious	-6,87	high_impact	3,9	damaging	0,51	damaging	0,02	deleterious	4,16	23,8	0,34	0,5	disease	0,84	disease	0,95	disease	0,74	disease	0,84	7	neutral	0,97	neutral	0,36	deleterious	2	deleterious	0,9	low_impact	-2,19	medium_impact	0,4	high_impact	2,13	0,35	0,8	54,08	11,58	P	0,57	P	0,98	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10537	10537	G	C	MI.15834	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	68	23	R	P	cGc/cCc	4,44	0,99	0	probably_damaging	0,99	neutral	0,2	neutral	1,5	deleterious	-6,24	deleterious	-6,88	high_impact	4,59	damaging	0,48	damaging	0,01	deleterious	4,04	23,7	0,29	0,45	disease	0,89	disease	0,93	disease	0,83	disease	0,88	8	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-2,63	medium_impact	-0,12	high_impact	2,71	0,32	0,8	54,08	11,58	P	0,67	P	0,97	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10537	10537	G	A	MI.15835	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	68	23	R	H	cGc/cAc	4,44	0,99	0	possibly_damaging	0,46	neutral	0,57	neutral	1,52	deleterious	-5,51	deleterious	-4,9	medium_impact	3,12	damaging	0,49	damaging	0,06	deleterious	3,8	23,4	0,49	0,55	disease	0,88	disease	0,87	disease	0,61	disease	0,7	4	neutral	0,43	deleterious	0,56	NA	0	deleterious	0,89	medium_impact	-0,74	medium_impact	0,28	medium_impact	1,48	0,73	0,85	54,08	11,58	P	0,54	P	0,83	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10539	10539	T	C	MI.15836	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	70	24	S	P	Tca/Cca	-0,86	0	0	probably_damaging	0,96	neutral	0,22	neutral	1,9	neutral	-1,58	deleterious	-4,76	medium_impact	3,27	damaging	0,55	damaging	0,26	deleterious	3,83	23,4	0,35	0,5	disease	0,55	disease	0,86	disease	0,58	disease	0,78	6	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,76	low_impact	-2,07	medium_impact	-0,1	medium_impact	1,6	0,62	0,8	55,1	10,39	N	0,34	N	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10539	10539	T	G	MI.15837	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	70	24	S	A	Tca/Gca	-0,86	0	0	possibly_damaging	0,69	neutral	0,56	neutral	1,93	neutral	-0,85	deleterious	-2,84	medium_impact	2,02	neutral	0,8	neutral	0,76	deleterious	2,21	17,57	0,64	0,7	neutral	0,29	neutral	0,43	neutral	0,4	neutral	0,46	1	neutral	0,64	neutral	0,44	NA	0	neutral	0,42	low_impact	-1,12	medium_impact	0,27	medium_impact	0,56	0,64	0,8	55,1	10,39	N	0,3	N	0,42	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10539	10539	T	A	MI.15838	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	70	24	S	T	Tca/Aca	-0,86	0	0	benign	0,15	neutral	0,46	neutral	1,95	neutral	-0,61	deleterious	-2,82	low_impact	1,26	neutral	0,73	neutral	0,81	neutral	-0,51	0,21	0,56	0,6	neutral	0,26	neutral	0,08	neutral	0,17	neutral	0,29	4	neutral	0,46	deleterious	0,66	neutral	-6	neutral	0,12	medium_impact	-0,11	medium_impact	0,17	medium_impact	-0,08	0,81	0,85	55,1	10,39	N	0,48	N	0,69	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10540	10540	C	T	MI.15839	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	71	24	S	L	tCa/tTa	0,98	0	0	possibly_damaging	0,86	neutral	0,71	neutral	1,89	neutral	-2,08	deleterious	-5,71	medium_impact	2,29	neutral	0,79	neutral	0,46	deleterious	4,46	24,2	0,58	0,65	neutral	0,39	disease	0,74	neutral	0,43	disease	0,55	1	neutral	0,84	neutral	0,43	NA	0	deleterious	0,55	low_impact	-1,53	medium_impact	0,43	medium_impact	0,78	0,79	0,85	55,1	10,39	N	0,27	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8432	8432	A	T	MI.1584	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	67	23	I	F	Atc/Ttc	-5,89	0	0	benign	0,04	neutral	0,41	neutral	1,71	neutral	-2,91	deleterious	-2,85	medium_impact	2,54	neutral	0,99	neutral	0,72	neutral	1,72	14,5	0,32790408	0,85	disease	0,51	neutral	0,28	neutral	0,48	neutral	0,14	7	neutral	0,56	deleterious	0,69	neutral	-3	neutral	0,22	medium_impact	0,55	medium_impact	0,2	medium_impact	1,08	0,7	0,85	1,47	7,72	N	0,44	N	0,52	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10540	10540	C	G	MI.15840	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	71	24	S	W	tCa/tGa	0,98	0	0	probably_damaging	1	neutral	0,18	neutral	1,85	deleterious	-5,49	deleterious	-6,64	high_impact	3,61	neutral	0,72	neutral	0,36	deleterious	4,2	23,9	0,33	0,5	disease	0,83	disease	0,84	disease	0,6	disease	0,78	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,79	low_impact	-3,55	medium_impact	-0,16	medium_impact	1,89	0,55	0,8	55,1	10,39	N	0,34	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10542	10542	C	G	MI.15841	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	73	25	H	D	Cac/Gac	-9,85	0	0	probably_damaging	1	neutral	0,2	neutral	1,88	neutral	-0,92	deleterious	-8,81	high_impact	4,66	neutral	0,75	damaging	0,04	deleterious	3,78	23,4	0,37	0,5	disease	0,64	disease	0,86	disease	0,74	disease	0,78	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,55	medium_impact	-0,12	high_impact	2,77	0,52	0,8	56,12	12,15	N	0,53	P	0,99	disease_causing	0,78	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10542	10542	C	T	MI.15842	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	73	25	H	Y	Cac/Tac	-9,85	0	0	probably_damaging	1	neutral	1	neutral	1,75	deleterious	-3,58	deleterious	-5,88	medium_impact	3,46	neutral	0,71	damaging	0,1	deleterious	3,65	23,2	0,52	0,6	disease	0,77	disease	0,81	disease	0,69	disease	0,69	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,85	low_impact	-3,55	high_impact	1,88	medium_impact	1,76	0,45	0,8	56,12	12,15	N	0,21	N	0,97	disease_causing	0,57	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10542	10542	C	A	MI.15843	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	73	25	H	N	Cac/Aac	-9,85	0	0	probably_damaging	1	neutral	0,33	neutral	2,02	neutral	0,1	deleterious	-6,86	medium_impact	3,08	neutral	0,68	damaging	0,03	deleterious	3,85	23,4	0,58	0,65	disease	0,69	disease	0,78	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,82	low_impact	-3,55	medium_impact	0,04	medium_impact	1,44	0,62	0,8	56,12	12,15	N	0,28	N	0,98	disease_causing	0,52	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10543	10543	A	C	MI.15844	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	74	25	H	P	cAc/cCc	5,6	1	0	probably_damaging	1	neutral	0,2	neutral	1,76	deleterious	-3,42	deleterious	-9,8	high_impact	3,62	neutral	0,63	damaging	0,09	deleterious	3	22,2	0,38	0,5	neutral	0,4	disease	0,89	disease	0,78	disease	0,79	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-3,55	medium_impact	-0,12	medium_impact	1,9	0,35	0,8	56,12	12,15	P	0,61	P	0,99	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10543	10543	A	T	MI.15845	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	74	25	H	L	cAc/cTc	5,6	1	0	probably_damaging	1	neutral	0,74	neutral	1,76	deleterious	-3,28	deleterious	-10,78	high_impact	4,66	neutral	0,68	damaging	0,03	deleterious	3,59	23,2	0,39	0,5	disease	0,74	disease	0,9	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	0,46	high_impact	2,77	0,37	0,8	56,12	12,15	P	0,62	P	0,89	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10543	10543	A	G	MI.15846	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	74	25	H	R	cAc/cGc	5,6	1	0	probably_damaging	1	neutral	0,38	neutral	1,81	neutral	-1,93	deleterious	-7,84	high_impact	4,12	neutral	0,72	damaging	0,04	deleterious	2,77	21,2	0,53	0,6	disease	0,66	disease	0,83	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	0,09	high_impact	2,32	0,39	0,8	56,12	12,15	P	0,65	P	0,98	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	A10543G	LHON	-	+	Reported	1
chrM	10544	10544	C	G	MI.15847	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	75	25	H	Q	caC/caG	5,6	1	0	probably_damaging	1	neutral	0,3	neutral	1,8	neutral	-2,04	deleterious	-7,83	high_impact	3,98	neutral	0,68	damaging	0,05	deleterious	3,47	23	0,55	0,6	disease	0,7	disease	0,81	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-3,55	medium_impact	0,01	high_impact	2,2	0,7	0,85	56,12	12,15	P	0,65	P	0,99	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10544	10544	C	A	MI.15848	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	75	25	H	Q	caC/caA	5,6	1	0	probably_damaging	1	neutral	0,3	neutral	1,8	neutral	-2,04	deleterious	-7,83	high_impact	3,98	neutral	0,68	damaging	0,05	deleterious	3,81	23,4	0,55	0,6	disease	0,7	disease	0,81	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-3,55	medium_impact	0,01	high_impact	2,2	0,7	0,85	56,12	12,15	P	0,65	P	0,99	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10545	10545	C	G	MI.15849	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	76	26	L	V	Ctc/Gtc	-0,86	0	0	possibly_damaging	0,9	neutral	0,34	neutral	1,58	neutral	-1,42	neutral	-2,28	medium_impact	3,02	neutral	0,65	damaging	0,07	deleterious	3,26	22,8	0,52	0,6	neutral	0,46	disease	0,61	disease	0,68	disease	0,68	4	neutral	0,91	neutral	0,22	NA	0	deleterious	0,76	low_impact	-1,68	medium_impact	0,05	medium_impact	1,39	0,7	0,85	50	10,34	N	0,32	N	0,74	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8432	8432	A	C	MI.1585	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	67	23	I	L	Atc/Ctc	-5,89	0	0	benign	0	neutral	1	neutral	1,92	neutral	0,93	neutral	-0,79	neutral_impact	0,7	neutral	1	neutral	0,95	deleterious	0,23	4,94	0,44253433	0,85	neutral	0,11	neutral	0,12	neutral	0,33	neutral	0,06	9	neutral	0	deleterious	1	neutral	-6	neutral	0,15	high_impact	2,09	high_impact	1,98	medium_impact	-0,5	0,64	0,85	1,47	7,72	N	0,39	N	0,1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10545	10545	C	A	MI.15850	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	76	26	L	I	Ctc/Atc	-0,86	0	0	possibly_damaging	0,9	neutral	0,32	neutral	1,65	neutral	-1,09	neutral	-1,48	medium_impact	2,27	neutral	0,8	neutral	0,36	deleterious	4,08	23,7	0,38	0,5	neutral	0,31	disease	0,63	disease	0,55	disease	0,58	1	neutral	0,91	neutral	0,21	NA	0	deleterious	0,73	low_impact	-1,68	medium_impact	0,03	medium_impact	0,77	0,69	0,85	50	10,34	N	0,35	N	0,54	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10545	10545	C	T	MI.15851	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	76	26	L	F	Ctc/Ttc	-0,86	0	0	possibly_damaging	0,5	neutral	0,52	neutral	1,52	deleterious	-3,48	deleterious	-2,95	medium_impact	2,08	neutral	0,82	neutral	0,43	deleterious	3,7	23,3	0,46	0,55	disease	0,62	neutral	0,44	neutral	0,44	disease	0,56	1	neutral	0,49	deleterious	0,51	NA	0	deleterious	0,77	medium_impact	-0,8	medium_impact	0,23	medium_impact	0,61	0,61	0,8	50	10,34	N	0,28	N	0,85	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10546	10546	T	C	MI.15852	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	77	26	L	P	cTc/cCc	-0,86	0	0	probably_damaging	1	neutral	0,13	neutral	1,47	deleterious	-5,87	deleterious	-6,08	high_impact	4,54	damaging	0,51	damaging	0,06	deleterious	3,76	23,3	0,16	0,45	disease	0,91	disease	0,86	disease	0,78	disease	0,87	7	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,25	high_impact	2,67	0,54	0,8	50	10,34	N	0,5	N	0,96	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10546	10546	T	G	MI.15853	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	77	26	L	R	cTc/cGc	-0,86	0	0	probably_damaging	0,99	neutral	0,29	neutral	1,48	deleterious	-5,36	deleterious	-5,14	high_impact	4,54	damaging	0,57	damaging	0,04	deleterious	4,05	23,7	0,08	0,35	disease	0,89	disease	0,87	disease	0,77	disease	0,86	7	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,9	low_impact	-2,63	medium_impact	-0,01	high_impact	2,67	0,42	0,8	50	10,34	N	0,52	P	0,97	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10546	10546	T	A	MI.15854	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	77	26	L	H	cTc/cAc	-0,86	0	0	probably_damaging	1	neutral	0,43	neutral	1,47	deleterious	-6,03	deleterious	-5,91	high_impact	4,54	neutral	0,65	damaging	0,05	deleterious	3,99	23,6	0,12	0,4	disease	0,93	disease	0,84	disease	0,75	disease	0,85	7	deleterious	0,99	neutral	0,22	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	0,14	high_impact	2,67	0,52	0,8	50	10,34	N	0,45	N	0,98	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10548	10548	A	G	MI.15855	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	79	27	M	V	Ata/Gta	-4,09	0	0	benign	0,02	neutral	0,32	neutral	1,94	neutral	1,72	deleterious	-3,67	medium_impact	2,17	neutral	0,82	neutral	0,64	neutral	-0,36	0,47	0,49	0,55	neutral	0,35	disease	0,55	neutral	0,4	neutral	0,49	0	neutral	0,67	deleterious	0,65	neutral	-3	neutral	0,17	medium_impact	0,75	medium_impact	0,03	medium_impact	0,68	0,59	0,8	54,08	11,45	N	0,37	N	0,06	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10548	10548	A	C	MI.15856	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	79	27	M	L	Ata/Cta	-4,09	0	0	benign	0,06	neutral	1	neutral	2,27	neutral	1,87	deleterious	-2,83	neutral_impact	0,36	neutral	0,72	neutral	0,7	neutral	-0,87	0,03	0,41	0,5	neutral	0,11	neutral	0,28	neutral	0,32	neutral	0,43	1	neutral	0,06	deleterious	0,97	neutral	-6	neutral	0,12	medium_impact	0,29	high_impact	1,88	medium_impact	-0,84	0,59	0,8	54,08	11,45	N	0,33	N	0,15	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10548	10548	A	T	MI.15857	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	79	27	M	L	Ata/Tta	-4,09	0	0	benign	0,06	neutral	1	neutral	2,27	neutral	1,87	deleterious	-2,83	neutral_impact	0,36	neutral	0,72	neutral	0,7	neutral	-0,77	0,05	0,41	0,5	neutral	0,11	neutral	0,28	neutral	0,32	neutral	0,43	1	neutral	0,06	deleterious	0,97	neutral	-6	neutral	0,12	medium_impact	0,29	high_impact	1,88	medium_impact	-0,84	0,59	0,8	54,08	11,45	N	0,33	N	0,15	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10549	10549	T	A	MI.15858	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	80	27	M	K	aTa/aAa	1,21	0,55	0	possibly_damaging	0,78	neutral	0,24	neutral	1,76	deleterious	-3,17	deleterious	-5,78	high_impact	3,77	neutral	0,73	neutral	0,32	deleterious	3,59	23,2	0,14	0,4	disease	0,81	disease	0,8	disease	0,69	disease	0,79	6	neutral	0,85	neutral	0,23	deleterious	1	deleterious	0,67	low_impact	-1,31	medium_impact	-0,07	high_impact	2,02	0,31	0,8	54,08	11,45	N	0,39	N	0,84	polymorphism	0,99	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10549	10549	T	C	MI.15859	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	80	27	M	T	aTa/aCa	1,21	0,55	0	possibly_damaging	0,44	neutral	0,19	neutral	1,81	neutral	-1,7	deleterious	-5,69	high_impact	3,77	neutral	0,76	neutral	0,45	neutral	1,18	11,65	0,35	0,5	disease	0,65	disease	0,6	disease	0,63	disease	0,73	5	neutral	0,78	neutral	0,38	deleterious	1	deleterious	0,46	medium_impact	-0,71	medium_impact	-0,14	high_impact	2,02	0,28	0,8	54,08	11,45	N	0,32	N	0,57	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8433	8433	T	G	MI.1586	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	68	23	I	S	aTc/aGc	-2,42	0	0,01	benign	0,05	neutral	0,08	neutral	1,64	deleterious	-4,31	deleterious	-4,33	medium_impact	3,35	neutral	0,99	neutral	0,43	deleterious	2,25	17,82	0,25608775	0,85	disease	0,64	neutral	0,45	disease	0,61	neutral	0,29	4	neutral	0,91	deleterious	0,52	neutral	-3	neutral	0,27	medium_impact	0,46	medium_impact	-0,31	medium_impact	1,77	0,62	0,85	1,47	7,72	N	0,51	P	0,72	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10550	10550	A	T	MI.15860	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	81	27	M	I	atA/atT	7,44	0,98	0,06	benign	0,02	neutral	0,34	neutral	2,02	neutral	1,74	deleterious	-3,7	low_impact	1,48	neutral	0,8	neutral	0,8	neutral	-0,09	1,81	0,47	0,55	neutral	0,23	neutral	0,46	neutral	0,34	neutral	0,46	1	neutral	0,64	deleterious	0,66	neutral	-6	neutral	0,15	medium_impact	0,75	medium_impact	0,05	medium_impact	0,1	0,65	0,8	54,08	11,45	P	0,6	P	0,19	polymorphism	0,99	0,09	rs28358280	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10550	10550	A	C	MI.15861	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	81	27	M	I	atA/atC	7,44	0,98	0,06	benign	0,02	neutral	0,34	neutral	2,02	neutral	1,74	deleterious	-3,7	low_impact	1,48	neutral	0,8	neutral	0,8	neutral	-0,19	1,16	0,47	0,55	neutral	0,23	neutral	0,46	neutral	0,34	neutral	0,46	1	neutral	0,64	deleterious	0,66	neutral	-6	neutral	0,15	medium_impact	0,75	medium_impact	0,05	medium_impact	0,1	0,65	0,8	54,08	11,45	P	0,59	P	0,19	polymorphism	0,99	0,09	rs28358280	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10551	10551	T	A	MI.15862	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	82	28	S	T	Tcc/Acc	-1,09	0,02	0	possibly_damaging	0,74	neutral	0,15	neutral	1,85	neutral	-1,78	deleterious	-2,87	medium_impact	2,9	neutral	0,72	neutral	0,52	neutral	1,71	14,47	0,48	0,55	disease	0,56	disease	0,72	disease	0,51	disease	0,53	1	neutral	0,89	neutral	0,21	NA	0	deleterious	0,7	low_impact	-1,22	medium_impact	-0,21	medium_impact	1,29	0,76	0,85	48,98	10,12	N	0,4	N	0,48	disease_causing	0,94	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10551	10551	T	C	MI.15863	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	82	28	S	P	Tcc/Ccc	-1,09	0,02	0	probably_damaging	0,96	neutral	0,07	neutral	1,8	deleterious	-3,58	deleterious	-4,82	high_impact	3,79	neutral	0,63	neutral	0,46	deleterious	3,75	23,3	0,16	0,45	disease	0,74	disease	0,87	disease	0,73	disease	0,79	6	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,83	low_impact	-2,07	medium_impact	-0,41	high_impact	2,04	0,73	0,85	48,98	10,12	N	0,42	N	0,83	disease_causing	0,99	0,18	.	.	.	.	.	endometrium tumor	.	.	.	.	.	.	.	.	.
chrM	10551	10551	T	G	MI.15864	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	82	28	S	A	Tcc/Gcc	-1,09	0,02	0	benign	0,08	neutral	0,18	neutral	1,85	neutral	-1,69	deleterious	-2,72	medium_impact	2,55	neutral	0,83	neutral	0,68	neutral	1,58	13,75	0,4	0,5	neutral	0,46	disease	0,68	neutral	0,38	disease	0,5	0	neutral	0,8	deleterious	0,55	neutral	-3	neutral	0,26	medium_impact	0,17	medium_impact	-0,16	medium_impact	1	0,75	0,85	48,98	10,12	N	0,43	N	0,01	disease_causing	0,84	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10552	10552	C	T	MI.15865	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	83	28	S	F	tCc/tTc	5,83	1	0	probably_damaging	0,98	neutral	0,22	neutral	1,8	deleterious	-3,6	deleterious	-5,79	high_impact	3,99	neutral	0,64	neutral	0,35	deleterious	4	23,6	0,21	0,45	disease	0,85	disease	0,85	disease	0,64	disease	0,78	6	deleterious	0,98	neutral	0,12	deleterious	2	deleterious	0,84	low_impact	-2,35	medium_impact	-0,1	high_impact	2,21	0,52	0,8	48,98	10,12	P	0,66	P	0,96	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10552	10552	C	G	MI.15866	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	83	28	S	C	tCc/tGc	5,83	1	0	probably_damaging	0,98	neutral	0,09	neutral	1,79	deleterious	-4,25	deleterious	-4,79	high_impact	3,54	neutral	0,73	neutral	0,35	deleterious	3,38	22,9	0,23	0,45	disease	0,84	disease	0,8	disease	0,6	disease	0,74	5	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,8	low_impact	-2,35	medium_impact	-0,35	medium_impact	1,83	0,77	0,85	48,98	10,12	P	0,64	P	0,56	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10552	10552	C	A	MI.15867	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	83	28	S	Y	tCc/tAc	5,83	1	0	probably_damaging	0,98	neutral	0,31	neutral	1,79	deleterious	-3,9	deleterious	-5,79	high_impact	3,64	neutral	0,71	neutral	0,53	deleterious	4,02	23,6	0,18	0,45	disease	0,85	disease	0,87	disease	0,56	disease	0,76	5	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-2,35	medium_impact	0,02	medium_impact	1,91	0,68	0,85	48,98	10,12	P	0,65	P	0,97	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10554	10554	T	A	MI.15868	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	85	29	S	T	Tcc/Acc	-20	0	0	probably_damaging	1	neutral	0,23	neutral	2,04	neutral	0,6	neutral	-1,4	neutral_impact	-0,24	neutral	0,83	neutral	0,99	deleterious	2,13	17,04	0,38	0,5	neutral	0,16	neutral	0,23	neutral	0,28	neutral	0,42	2	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,67	low_impact	-3,55	medium_impact	-0,08	low_impact	-1,34	0,73	0,85	26,53	15,35	N	0,37	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10554	10554	T	C	MI.15869	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	85	29	S	P	Tcc/Ccc	-20	0	0	probably_damaging	1	neutral	0,06	neutral	1,94	neutral	-2,5	deleterious	-4,13	medium_impact	3,29	damaging	0,56	neutral	0,37	deleterious	3,85	23,4	0,17	0,45	neutral	0,48	disease	0,86	disease	0,65	disease	0,8	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,81	low_impact	-3,55	medium_impact	-0,45	medium_impact	1,62	0,73	0,85	26,53	15,35	N	0,37	N	0,81	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8433	8433	T	A	MI.1587	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	68	23	I	N	aTc/aAc	-2,42	0	0,01	benign	0,23	deleterious	0,04	neutral	1,63	deleterious	-5,36	deleterious	-5,33	medium_impact	3,35	neutral	1	neutral	0,46	deleterious	2,5	19,48	0,23666041	0,85	disease	0,78	neutral	0,48	disease	0,65	neutral	0,41	2	neutral	0,95	neutral	0,41	deleterious	1	neutral	0,43	medium_impact	-0,26	medium_impact	-0,49	medium_impact	1,77	0,66	0,85	1,47	7,72	N	0,49	N	0,82	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10554	10554	T	G	MI.15870	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	85	29	S	A	Tcc/Gcc	-20	0	0	probably_damaging	1	neutral	0,59	neutral	2,07	neutral	0,91	neutral	-2,14	neutral_impact	0,53	neutral	0,75	neutral	0,95	deleterious	0,88	9,96	0,46	0,55	neutral	0,12	neutral	0,15	neutral	0,25	neutral	0,24	5	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,65	low_impact	-3,55	medium_impact	0,3	medium_impact	-0,69	0,71	0,85	26,53	15,35	N	0,32	N	0,3	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10555	10555	C	T	MI.15871	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	86	29	S	F	tCc/tTc	0,52	0,3	0	probably_damaging	1	neutral	0,22	neutral	1,97	neutral	-0,78	deleterious	-5,1	medium_impact	2,59	damaging	0,57	neutral	0,46	deleterious	4,14	23,8	0,29	0,45	neutral	0,34	disease	0,7	disease	0,56	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,73	low_impact	-3,55	medium_impact	-0,1	medium_impact	1,03	0,5	0,8	26,53	15,35	N	0,38	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10555	10555	C	G	MI.15872	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	86	29	S	C	tCc/tGc	0,52	0,3	0	probably_damaging	1	neutral	0,16	neutral	1,94	neutral	-2,4	deleterious	-4,07	medium_impact	2,04	neutral	0,62	neutral	0,38	deleterious	3,49	23,1	0,21	0,45	disease	0,52	disease	0,63	disease	0,52	disease	0,61	2	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,72	low_impact	-3,55	medium_impact	-0,19	medium_impact	0,57	0,71	0,85	26,53	15,35	N	0,33	N	0,52	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10555	10555	C	A	MI.15873	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	86	29	S	Y	tCc/tAc	0,52	0,3	0	probably_damaging	1	neutral	0,24	neutral	1,95	neutral	-1,57	deleterious	-5,1	medium_impact	2,94	neutral	0,68	neutral	0,46	deleterious	3,94	23,5	0,25	0,45	neutral	0,4	disease	0,69	disease	0,55	disease	0,7	4	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,74	low_impact	-3,55	medium_impact	-0,07	medium_impact	1,33	0,69	0,85	26,53	15,35	N	0,38	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10557	10557	C	G	MI.15874	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	88	30	L	V	Cta/Gta	-9,85	0	0	probably_damaging	1	neutral	0,19	neutral	1,05	deleterious	-3,41	deleterious	-2,94	high_impact	4,76	damaging	0,52	damaging	0,1	deleterious	3,31	22,9	0,25	0,45	disease	0,62	disease	0,63	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,79	low_impact	-3,55	medium_impact	-0,14	high_impact	2,85	0,75	0,85	55,1	12,02	P	0,65	P	0,75	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10557	10557	C	A	MI.15875	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	88	30	L	M	Cta/Ata	-9,85	0	0	probably_damaging	1	neutral	0,29	neutral	0,95	deleterious	-5,28	neutral	-1,96	high_impact	3,87	damaging	0,59	damaging	0,1	deleterious	3,65	23,2	0,22	0,45	disease	0,69	disease	0,63	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,78	low_impact	-3,55	medium_impact	-0,01	high_impact	2,11	0,57	0,8	55,1	12,02	N	0,32	N	0,77	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10558	10558	T	A	MI.15876	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	89	30	L	Q	cTa/cAa	0,06	0	0	probably_damaging	1	deleterious	0,02	neutral	0,91	deleterious	-8,42	deleterious	-5,88	high_impact	4,76	damaging	0,44	damaging	0,07	deleterious	3,92	23,5	0,13	0,4	disease	0,9	disease	0,84	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,55	medium_impact	-0,73	high_impact	2,85	0,54	0,8	55,1	12,02	P	0,55	P	0,99	polymorphism	0,98	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10558	10558	T	G	MI.15877	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	89	30	L	R	cTa/cGa	0,06	0	0	probably_damaging	1	neutral	0,06	neutral	0,91	deleterious	-8,57	deleterious	-5,89	high_impact	4,76	damaging	0,46	damaging	0,06	deleterious	4,07	23,7	0,12	0,4	disease	0,89	disease	0,87	disease	0,8	disease	0,88	8	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,45	high_impact	2,85	0,39	0,8	55,1	12,02	P	0,57	P	0,99	polymorphism	0,98	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10558	10558	T	C	MI.15878	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	89	30	L	P	cTa/cCa	0,06	0	0	probably_damaging	1	deleterious	0,01	neutral	0,91	deleterious	-8,84	deleterious	-6,88	high_impact	4,76	damaging	0,38	damaging	0,07	deleterious	3,76	23,4	0,15	0,4	disease	0,92	disease	0,84	disease	0,8	disease	0,89	8	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-3,55	medium_impact	-0,9	high_impact	2,85	0,42	0,8	55,1	12,02	P	0,62	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10560	10560	C	A	MI.15879	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	91	31	L	M	Cta/Ata	-5,93	0	0	probably_damaging	1	neutral	0,21	neutral	1,5	neutral	-2,2	neutral	-1,88	medium_impact	3	neutral	0,76	damaging	0,2	deleterious	3,6	23,2	0,27	0,45	disease	0,56	disease	0,5	neutral	0,47	disease	0,51	0	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,74	low_impact	-3,55	medium_impact	-0,11	medium_impact	1,38	0,55	0,8	52,04	11,96	N	0,35	N	0,77	polymorphism	0,8	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8433	8433	T	C	MI.1588	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	68	23	I	T	aTc/aCc	-2,42	0	0,01	benign	0,02	deleterious	0,03	neutral	1,68	deleterious	-3,6	deleterious	-3,16	medium_impact	2,19	neutral	1	neutral	0,86	deleterious	0,23	5,04	0,46889253	0,85	neutral	0,45	neutral	0,32	neutral	0,5	neutral	0,18	6	neutral	0,97	deleterious	0,51	deleterious	1	neutral	0,22	medium_impact	0,85	medium_impact	-0,56	medium_impact	0,78	0,68	0,85	1,47	7,72	P	0,54	P	0,61	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10560	10560	C	G	MI.15880	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	91	31	L	V	Cta/Gta	-5,93	0	0	probably_damaging	1	neutral	0,18	neutral	1,43	neutral	-2,88	deleterious	-2,91	medium_impact	3,41	neutral	0,66	damaging	0,06	deleterious	3,3	22,8	0,25	0,45	neutral	0,44	disease	0,52	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,73	low_impact	-3,55	medium_impact	-0,16	medium_impact	1,72	0,54	0,8	52,04	11,96	N	0,34	N	0,75	polymorphism	0,76	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10561	10561	T	A	MI.15881	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	92	31	L	Q	cTa/cAa	-0,17	0	0	probably_damaging	1	neutral	0,06	neutral	1,33	deleterious	-6,93	deleterious	-5,82	high_impact	4,65	neutral	0,64	damaging	0,05	deleterious	4,12	23,8	0,17	0,45	disease	0,88	disease	0,79	disease	0,66	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	-0,45	high_impact	2,76	0,51	0,8	52,04	11,96	N	0,45	N	0,99	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10561	10561	T	G	MI.15882	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	92	31	L	R	cTa/cGa	-0,17	0	0	probably_damaging	1	neutral	0,07	neutral	1,33	deleterious	-6,93	deleterious	-5,84	high_impact	4,65	neutral	0,61	damaging	0,04	deleterious	4,02	23,6	0,15	0,4	disease	0,88	disease	0,82	disease	0,75	disease	0,83	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,41	high_impact	2,76	0,37	0,8	52,04	11,96	N	0,5	N	0,99	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10561	10561	T	C	MI.15883	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	92	31	L	P	cTa/cCa	-0,17	0	0	probably_damaging	1	deleterious	0,04	neutral	1,32	deleterious	-7,34	deleterious	-6,83	high_impact	4,65	damaging	0,54	damaging	0,05	deleterious	3,86	23,5	0,18	0,45	disease	0,91	disease	0,8	disease	0,75	disease	0,83	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-3,55	medium_impact	-0,56	high_impact	2,76	0,48	0,8	52,04	11,96	N	0,43	N	1	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10563	10563	T	C	MI.15884	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	94	32	C	R	Tgc/Cgc	-1,09	0,01	0	probably_damaging	1	neutral	0,14	neutral	1,74	deleterious	-4,77	deleterious	-11,74	high_impact	3,96	neutral	0,65	damaging	0,07	deleterious	3,34	22,9	0,25	0,45	disease	0,78	disease	0,91	disease	0,74	disease	0,8	6	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,23	high_impact	2,18	0,36	0,8	54,08	12,3	N	0,42	N	1	disease_causing_automatic	1	0,2	rs267606892	Pathogenic	Familial_colorectal_cancer	RCV000010352.2	MedGen	colorectal tumor	.	.	.	.	.	.	.	.	.
chrM	10563	10563	T	A	MI.15885	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	94	32	C	S	Tgc/Agc	-1,09	0,01	0	probably_damaging	1	neutral	0,3	neutral	2,05	neutral	-0,3	deleterious	-9,77	low_impact	1,12	neutral	0,69	damaging	0,17	deleterious	3,37	22,9	0,38	0,5	neutral	0,19	disease	0,82	neutral	0,49	disease	0,7	4	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,75	low_impact	-3,55	medium_impact	0,01	medium_impact	-0,2	0,7	0,85	54,08	12,3	N	0,32	N	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10563	10563	T	G	MI.15886	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	94	32	C	G	Tgc/Ggc	-1,09	0,01	0	probably_damaging	1	neutral	0,19	neutral	2,1	deleterious	-3,37	deleterious	-11,74	medium_impact	3,15	neutral	0,64	damaging	0,1	deleterious	3,16	22,6	0,31	0,5	disease	0,55	disease	0,86	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,82	low_impact	-3,55	medium_impact	-0,14	medium_impact	1,5	0,62	0,8	54,08	12,3	N	0,36	N	1	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10564	10564	G	T	MI.15887	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	95	32	C	F	tGc/tTc	4,44	1	0	probably_damaging	1	neutral	0,44	neutral	1,73	deleterious	-5,29	deleterious	-10,76	high_impact	3,75	neutral	0,63	damaging	0,06	deleterious	3,76	23,3	0,28	0,45	disease	0,82	disease	0,89	disease	0,66	disease	0,76	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,87	low_impact	-3,55	medium_impact	0,15	high_impact	2,01	0,54	0,8	54,08	12,3	N	0,52	P	0,99	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10564	10564	G	C	MI.15888	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	95	32	C	S	tGc/tCc	4,44	1	0	probably_damaging	1	neutral	0,3	neutral	2,05	neutral	-0,3	deleterious	-9,77	low_impact	1,12	neutral	0,69	damaging	0,17	deleterious	3,05	22,4	0,38	0,5	neutral	0,19	disease	0,82	neutral	0,49	disease	0,7	4	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,75	low_impact	-3,55	medium_impact	0,01	medium_impact	-0,2	0,7	0,85	54,08	12,3	N	0,41	N	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10564	10564	G	A	MI.15889	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	95	32	C	Y	tGc/tAc	4,44	1	0	probably_damaging	1	neutral	0,48	neutral	1,73	deleterious	-5,68	deleterious	-10,76	high_impact	3,96	neutral	0,71	damaging	0,08	deleterious	3,59	23,2	0,28	0,45	disease	0,86	disease	0,89	disease	0,68	disease	0,79	6	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	0,19	high_impact	2,18	0,51	0,8	54,08	12,3	N	0,55	P	0,99	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8434	8434	C	A	MI.1589	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	69	23	I	M	atC/atA	5,68	0,87	0,01	benign	0,08	neutral	0,17	neutral	1,68	neutral	-1,72	neutral	-1,05	low_impact	1,73	neutral	0,98	neutral	0,88	deleterious	0,59	8,09	0,43104827	0,85	neutral	0,47	neutral	0,17	neutral	0,43	neutral	0,06	9	neutral	0,81	deleterious	0,55	neutral	-6	neutral	0,24	medium_impact	0,25	medium_impact	-0,1	medium_impact	0,39	0,76	0,85	1,47	7,72	P	0,57	P	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10565	10565	C	A	MI.15890	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	96	32	C	W	tgC/tgA	6,06	1	0	probably_damaging	1	neutral	0,08	neutral	1,72	deleterious	-7,35	deleterious	-10,77	high_impact	4,3	neutral	0,71	damaging	0,07	deleterious	4,53	24,3	0,22	0,45	disease	0,94	disease	0,91	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,38	high_impact	2,47	0,42	0,8	54,08	12,3	P	0,58	P	0,99	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10565	10565	C	G	MI.15891	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	96	32	C	W	tgC/tgG	6,06	1	0	probably_damaging	1	neutral	0,08	neutral	1,72	deleterious	-7,35	deleterious	-10,77	high_impact	4,3	neutral	0,71	damaging	0,07	deleterious	4,21	23,9	0,22	0,45	disease	0,94	disease	0,91	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,38	high_impact	2,47	0,42	0,8	54,08	12,3	P	0,58	P	0,99	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10566	10566	C	G	MI.15892	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	97	33	L	V	Cta/Gta	-2,71	0	0	probably_damaging	1	neutral	0,13	neutral	1,52	neutral	-1,1	deleterious	-2,92	high_impact	3,62	neutral	0,78	damaging	0,19	deleterious	3,33	22,9	0,34	0,5	disease	0,62	neutral	0,46	disease	0,62	disease	0,58	2	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,75	low_impact	-3,55	medium_impact	-0,25	medium_impact	1,9	0,62	0,8	54,08	11,68	N	0,36	N	0,75	disease_causing	0,9	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10566	10566	C	A	MI.15893	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	97	33	L	M	Cta/Ata	-2,71	0	0	probably_damaging	1	neutral	0,21	neutral	1,49	deleterious	-3,81	neutral	-1,93	medium_impact	3,22	neutral	0,75	damaging	0,2	deleterious	3,6	23,2	0,29	0,45	disease	0,69	neutral	0,45	disease	0,6	disease	0,6	2	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	-0,11	medium_impact	1,56	0,6	0,8	54,08	11,68	N	0,37	N	0,77	disease_causing	0,88	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10567	10567	T	C	MI.15894	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	98	33	L	P	cTa/cCa	-1,32	0	0	probably_damaging	1	deleterious	0,01	neutral	1,41	deleterious	-6,48	deleterious	-6,86	high_impact	4,66	damaging	0,57	damaging	0,04	deleterious	3,8	23,4	0,21	0,45	disease	0,92	disease	0,79	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,55	medium_impact	-0,9	high_impact	2,77	0,48	0,8	54,08	11,68	N	0,44	N	1	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10567	10567	T	G	MI.15895	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	98	33	L	R	cTa/cGa	-1,32	0	0	probably_damaging	1	deleterious	0,02	neutral	1,42	deleterious	-6,08	deleterious	-5,87	high_impact	4,66	neutral	0,62	damaging	0,04	deleterious	4,07	23,7	0,17	0,45	disease	0,89	disease	0,82	disease	0,76	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,55	medium_impact	-0,73	high_impact	2,77	0,43	0,8	54,08	11,68	N	0,49	N	0,99	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10567	10567	T	A	MI.15896	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	98	33	L	Q	cTa/cAa	-1,32	0	0	probably_damaging	1	neutral	0,05	neutral	1,41	deleterious	-6,1	deleterious	-5,86	high_impact	4,66	neutral	0,64	damaging	0,05	deleterious	3,96	23,6	0,18	0,45	disease	0,9	disease	0,75	disease	0,67	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,83	low_impact	-3,55	medium_impact	-0,5	high_impact	2,77	0,57	0,8	54,08	11,68	N	0,45	N	0,99	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10569	10569	G	A	MI.15897	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	100	34	E	K	Gaa/Aaa	0,06	0,92	0	benign	0,29	neutral	0,29	neutral	1,54	deleterious	-5,94	deleterious	-3,92	high_impact	4,78	damaging	0,42	damaging	0,26	deleterious	2,62	20,3	0,33	0,5	disease	0,75	disease	0,86	disease	0,84	disease	0,82	6	neutral	0,65	deleterious	0,5	neutral	-2	neutral	0,43	medium_impact	-0,45	medium_impact	-0,01	high_impact	2,87	0,54	0,8	55,1	12,25	P	0,74	P	1	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10569	10569	G	C	MI.15898	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	100	34	E	Q	Gaa/Caa	0,06	0,92	0	probably_damaging	0,91	neutral	0,29	neutral	1,51	deleterious	-6,32	deleterious	-2,94	high_impact	4,78	damaging	0,41	neutral	0,39	deleterious	3,15	22,6	0,39	0,5	disease	0,79	disease	0,74	disease	0,78	disease	0,8	6	neutral	0,93	neutral	0,19	deleterious	2	deleterious	0,79	low_impact	-1,72	medium_impact	-0,01	high_impact	2,87	0,68	0,85	55,1	12,25	P	0,79	P	0,84	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10570	10570	A	G	MI.15899	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	101	34	E	G	gAa/gGa	9,05	1	0	probably_damaging	0,96	neutral	0,33	neutral	1,57	deleterious	-6,43	deleterious	-6,85	high_impact	4,42	damaging	0,46	neutral	0,51	deleterious	4,04	23,7	0,3	0,45	disease	0,78	disease	0,73	disease	0,76	disease	0,75	5	neutral	0,96	neutral	0,19	deleterious	2	deleterious	0,83	low_impact	-2,07	medium_impact	0,04	high_impact	2,57	0,31	0,8	55,1	12,25	P	0,67	P	0,73	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8600	8600	T	G	MI.159	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	74	25	L	R	cTa/cGa	-2,19	0	0	probably_damaging	1	deleterious	0,03	neutral	4,13	deleterious	-3,51	deleterious	-3,3	medium_impact	3	neutral	0,8	neutral	0,45	deleterious	3,9	23,5	0,18	0,65	disease	0,58	disease	0,69	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-3,6	medium_impact	-0,56	medium_impact	1,47	0,52	0,9	10,18	13,06	N	0,32	N	0,85	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8434	8434	C	G	MI.1590	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	69	23	I	M	atC/atG	5,68	0,87	0,01	benign	0,08	neutral	0,17	neutral	1,68	neutral	-1,72	neutral	-1,05	low_impact	1,73	neutral	0,98	neutral	0,88	deleterious	0,15	4,1	0,43104827	0,85	neutral	0,47	neutral	0,17	neutral	0,43	neutral	0,06	9	neutral	0,81	deleterious	0,55	neutral	-6	neutral	0,24	medium_impact	0,25	medium_impact	-0,1	medium_impact	0,39	0,76	0,85	1,47	7,72	P	0,57	P	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10570	10570	A	C	MI.15900	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	101	34	E	A	gAa/gCa	9,05	1	0	probably_damaging	0,91	neutral	0,51	neutral	1,54	deleterious	-6,2	deleterious	-5,86	high_impact	4,78	damaging	0,51	neutral	0,4	deleterious	3,43	23	0,23	0,45	disease	0,78	disease	0,68	disease	0,75	disease	0,77	5	neutral	0,9	neutral	0,3	deleterious	2	deleterious	0,78	low_impact	-1,72	medium_impact	0,22	high_impact	2,87	0,43	0,8	55,1	12,25	P	0,68	P	0,84	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10570	10570	A	T	MI.15901	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	101	34	E	V	gAa/gTa	9,05	1	0	probably_damaging	0,98	neutral	0,5	neutral	1,49	deleterious	-7,36	deleterious	-6,86	high_impact	4,78	damaging	0,43	neutral	0,29	deleterious	3,94	23,6	0,24	0,45	disease	0,88	disease	0,83	disease	0,78	disease	0,85	7	neutral	0,98	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-2,35	medium_impact	0,21	high_impact	2,87	0,46	0,8	55,1	12,25	P	0,78	P	0,89	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10571	10571	A	T	MI.15902	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	102	34	E	D	gaA/gaT	6,75	1	0	possibly_damaging	0,89	neutral	0,2	neutral	1,53	deleterious	-5,15	deleterious	-2,94	high_impact	4,78	damaging	0,48	neutral	0,38	deleterious	3,69	23,3	0,41	0,5	disease	0,63	disease	0,73	disease	0,79	disease	0,77	5	neutral	0,93	neutral	0,16	deleterious	1	deleterious	0,76	low_impact	-1,64	medium_impact	-0,12	high_impact	2,87	0,7	0,85	55,1	12,25	P	0,79	P	0,83	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10571	10571	A	C	MI.15903	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	102	34	E	D	gaA/gaC	6,75	1	0	possibly_damaging	0,89	neutral	0,2	neutral	1,53	deleterious	-5,15	deleterious	-2,94	high_impact	4,78	damaging	0,48	neutral	0,38	deleterious	3,56	23,1	0,41	0,5	disease	0,63	disease	0,73	disease	0,79	disease	0,77	5	neutral	0,93	neutral	0,16	deleterious	1	deleterious	0,76	low_impact	-1,64	medium_impact	-0,12	high_impact	2,87	0,7	0,85	55,1	12,25	P	0,79	P	0,83	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10572	10572	G	C	MI.15904	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	103	35	G	R	Gga/Cga	0,06	0,81	0	probably_damaging	1	neutral	0,34	neutral	1,86	deleterious	-3,04	deleterious	-7,61	high_impact	4,04	neutral	0,67	damaging	0,16	deleterious	3,86	23,4	0,21	0,45	neutral	0,47	disease	0,86	disease	0,67	disease	0,75	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-3,55	medium_impact	0,05	high_impact	2,25	0,64	0,8	54,08	11,89	N	0,41	N	0,99	disease_causing	0,93	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10572	10572	G	T	MI.15905	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	103	35	G	W	Gga/Tga	0,06	0,81	0	probably_damaging	1	neutral	0,18	neutral	1,85	deleterious	-4,3	deleterious	-7,69	high_impact	4,04	neutral	0,71	damaging	0,17	deleterious	4,31	24	0,27	0,45	disease	0,72	disease	0,85	disease	0,64	disease	0,73	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,78	low_impact	-3,55	medium_impact	-0,16	high_impact	2,25	0,4	0,8	54,08	11,89	N	0,42	N	0,99	disease_causing	0,96	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10573	10573	G	A	MI.15906	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	104	35	G	E	gGa/gAa	2,83	1	0	probably_damaging	1	neutral	0,34	neutral	1,86	deleterious	-3,33	deleterious	-7,57	high_impact	4,04	neutral	0,72	damaging	0,24	deleterious	3,8	23,4	0,33	0,5	neutral	0,41	disease	0,81	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,76	low_impact	-3,55	medium_impact	0,05	high_impact	2,25	0,55	0,8	54,08	11,89	N	0,52	P	0,99	disease_causing	0,94	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10573	10573	G	C	MI.15907	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	104	35	G	A	gGa/gCa	2,83	1	0	probably_damaging	1	neutral	0,54	neutral	1,93	neutral	-0,95	deleterious	-5,63	low_impact	1,67	neutral	0,75	neutral	0,57	deleterious	2,92	21,9	0,52	0,6	neutral	0,32	neutral	0,47	neutral	0,37	neutral	0,42	2	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,7	low_impact	-3,55	medium_impact	0,25	medium_impact	0,26	0,69	0,85	54,08	11,89	N	0,42	N	0,98	disease_causing	0,86	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10573	10573	G	T	MI.15908	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	104	35	G	V	gGa/gTa	2,83	1	0	probably_damaging	1	neutral	0,55	neutral	2	neutral	-0,02	deleterious	-8,59	medium_impact	3,06	neutral	0,73	damaging	0,25	deleterious	3,65	23,2	0,35	0,5	neutral	0,33	disease	0,8	disease	0,59	disease	0,7	4	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,73	low_impact	-3,55	medium_impact	0,26	medium_impact	1,43	0,49	0,8	54,08	11,89	N	0,39	N	1	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10575	10575	A	T	MI.15909	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	106	36	M	L	Ata/Tta	-9,85	0	0	benign	0,12	neutral	1	neutral	1,88	neutral	-0,85	deleterious	-2,73	medium_impact	2,31	neutral	0,84	neutral	0,71	neutral	1,43	12,94	0,49	0,55	neutral	0,23	disease	0,75	disease	0,56	disease	0,55	1	neutral	0,12	deleterious	0,94	neutral	-3	neutral	0,21	medium_impact	-0,01	high_impact	1,88	medium_impact	0,8	0,52	0,8	56,12	11,55	N	0,26	N	0,52	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8435	8435	A	C	MI.1591	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	70	24	T	P	Acc/Ccc	-4,5	0	0,01	possibly_damaging	0,66	neutral	0,2	neutral	1,93	deleterious	-5,61	deleterious	-2,74	medium_impact	2,51	neutral	0,99	neutral	0,41	deleterious	2,95	22,1	0,2785712	0,85	disease	0,57	disease	0,55	disease	0,68	disease	0,63	3	neutral	0,82	neutral	0,27	NA	0	deleterious	0,62	low_impact	-1,03	medium_impact	-0,05	medium_impact	1,05	0,68	0,85	NA	NA	N	0,51	P	0,61	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10575	10575	A	C	MI.15910	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	106	36	M	L	Ata/Cta	-9,85	0	0	benign	0,12	neutral	1	neutral	1,88	neutral	-0,85	deleterious	-2,73	medium_impact	2,31	neutral	0,84	neutral	0,71	neutral	1,32	12,39	0,49	0,55	neutral	0,23	disease	0,75	disease	0,56	disease	0,55	1	neutral	0,12	deleterious	0,94	neutral	-3	neutral	0,21	medium_impact	-0,01	high_impact	1,88	medium_impact	0,8	0,52	0,8	56,12	11,55	N	0,26	N	0,52	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10575	10575	A	G	MI.15911	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	106	36	M	V	Ata/Gta	-9,85	0	0	benign	0,18	neutral	0,37	neutral	1,72	neutral	-1,48	deleterious	-3,63	medium_impact	2,98	neutral	0,75	neutral	0,59	deleterious	0,84	9,69	0,62	0,65	neutral	0,18	disease	0,74	disease	0,59	disease	0,63	3	neutral	0,56	deleterious	0,6	neutral	-3	neutral	0,2	medium_impact	-0,2	medium_impact	0,08	medium_impact	1,36	0,42	0,8	56,12	11,55	N	0,38	N	0,48	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10576	10576	T	A	MI.15912	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	107	36	M	K	aTa/aAa	3,98	0,99	0	possibly_damaging	0,84	neutral	0,12	neutral	1,63	deleterious	-5,19	deleterious	-5,7	high_impact	4,39	neutral	0,67	neutral	0,35	deleterious	3,81	23,4	0,22	0,45	disease	0,77	disease	0,89	disease	0,75	disease	0,8	6	neutral	0,94	neutral	0,14	deleterious	1	deleterious	0,71	low_impact	-1,46	medium_impact	-0,27	high_impact	2,54	0,33	0,8	56,12	11,55	P	0,62	P	0,87	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10576	10576	T	C	MI.15913	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	107	36	M	T	aTa/aCa	3,98	0,99	0	possibly_damaging	0,73	neutral	0,19	neutral	1,67	deleterious	-3,96	deleterious	-5,58	medium_impact	3,5	neutral	0,82	neutral	0,55	deleterious	2,52	19,62	0,51	0,6	disease	0,59	disease	0,77	disease	0,68	disease	0,66	3	neutral	0,86	neutral	0,23	NA	0	deleterious	0,54	low_impact	-1,2	medium_impact	-0,14	medium_impact	1,8	0,32	0,8	56,12	11,55	P	0,57	P	0,42	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10577	10577	A	T	MI.15914	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	108	36	M	I	atA/atT	7,44	1	0	benign	0,03	neutral	0,31	neutral	1,94	neutral	-0,87	deleterious	-3,59	low_impact	1,8	neutral	0,92	neutral	0,64	deleterious	0,37	6,33	0,5	0,6	neutral	0,2	disease	0,79	disease	0,54	disease	0,55	1	neutral	0,67	deleterious	0,64	neutral	-6	neutral	0,18	medium_impact	0,58	medium_impact	0,02	medium_impact	0,37	0,56	0,8	56,12	11,55	P	0,61	P	0,05	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10577	10577	A	C	MI.15915	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	108	36	M	I	atA/atC	7,44	1	0	benign	0,03	neutral	0,31	neutral	1,94	neutral	-0,87	deleterious	-3,59	low_impact	1,8	neutral	0,92	neutral	0,64	deleterious	0,31	5,78	0,5	0,6	neutral	0,2	disease	0,79	disease	0,54	disease	0,55	1	neutral	0,67	deleterious	0,64	neutral	-6	neutral	0,18	medium_impact	0,58	medium_impact	0,02	medium_impact	0,37	0,56	0,8	56,12	11,55	P	0,61	P	0,05	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10578	10578	A	C	MI.15916	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	109	37	M	L	Ata/Cta	0,29	0,98	0	benign	0,02	neutral	0,86	neutral	2,01	neutral	1,65	deleterious	-2,67	medium_impact	2,06	neutral	0,83	neutral	0,56	neutral	1,3	12,29	0,62	0,65	neutral	0,14	disease	0,78	disease	0,52	disease	0,62	2	neutral	0,1	deleterious	0,92	neutral	-3	neutral	0,2	medium_impact	0,75	medium_impact	0,65	medium_impact	0,59	0,48	0,8	56,12	10,37	N	0,36	N	0,47	polymorphism	0,65	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10578	10578	A	T	MI.15917	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	109	37	M	L	Ata/Tta	0,29	0,98	0	benign	0,02	neutral	0,86	neutral	2,01	neutral	1,65	deleterious	-2,67	medium_impact	2,06	neutral	0,83	neutral	0,56	neutral	1,37	12,65	0,62	0,65	neutral	0,14	disease	0,78	disease	0,52	disease	0,62	2	neutral	0,1	deleterious	0,92	neutral	-3	neutral	0,2	medium_impact	0,75	medium_impact	0,65	medium_impact	0,59	0,48	0,8	56,12	10,37	N	0,36	N	0,47	polymorphism	0,65	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10578	10578	A	G	MI.15918	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	109	37	M	V	Ata/Gta	0,29	0,98	0	benign	0,1	neutral	0,31	neutral	1,88	neutral	-0,05	deleterious	-3,52	low_impact	1,52	neutral	0,85	neutral	0,71	deleterious	0,81	9,5	0,7	0,75	neutral	0,12	disease	0,72	disease	0,51	disease	0,53	1	neutral	0,65	deleterious	0,61	neutral	-6	neutral	0,18	medium_impact	0,07	medium_impact	0,02	medium_impact	0,14	0,28	0,8	56,12	10,37	N	0,41	N	0,15	polymorphism	0,6	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10579	10579	T	C	MI.15919	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	110	37	M	T	aTa/aCa	3,98	1	0	benign	0,04	neutral	0,13	neutral	1,86	neutral	-2,85	deleterious	-5,48	medium_impact	2,69	neutral	0,83	neutral	0,63	neutral	0,99	10,63	0,64	0,7	disease	0,54	disease	0,76	disease	0,57	disease	0,64	3	neutral	0,86	deleterious	0,55	neutral	-3	neutral	0,27	medium_impact	0,46	medium_impact	-0,25	medium_impact	1,12	0,28	0,8	56,12	10,37	N	0,52	P	0,63	disease_causing	0,73	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8435	8435	A	G	MI.1592	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	70	24	T	A	Acc/Gcc	-4,5	0	0,01	benign	0,1	neutral	0,31	neutral	1,98	deleterious	-3,44	neutral	-1,14	low_impact	1,71	neutral	0,99	neutral	0,74	deleterious	0,37	6,33	0,5726291	0,85	neutral	0,24	neutral	0,16	disease	0,53	neutral	0,2	6	neutral	0,65	deleterious	0,61	neutral	-6	neutral	0,2	medium_impact	0,15	medium_impact	0,1	medium_impact	0,37	0,59	0,85	NA	NA	N	0,52	P	0,34	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10579	10579	T	A	MI.15920	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	110	37	M	K	aTa/aAa	3,98	1	0	possibly_damaging	0,57	deleterious	0,04	neutral	1,83	deleterious	-4,12	deleterious	-5,63	high_impact	4,3	neutral	0,64	neutral	0,36	deleterious	2,34	18,44	0,3	0,45	disease	0,72	disease	0,89	disease	0,74	disease	0,8	6	neutral	0,96	neutral	0,24	deleterious	5	deleterious	0,51	medium_impact	-0,92	medium_impact	-0,56	high_impact	2,47	0,39	0,8	56,12	10,37	P	0,6	P	0,9	disease_causing	0,95	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10580	10580	A	C	MI.15921	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	111	37	M	I	atA/atC	5,83	1	0	benign	0,02	neutral	0,36	neutral	1,86	neutral	-0,69	deleterious	-3,5	medium_impact	2,54	neutral	0,89	neutral	0,74	neutral	1,32	12,39	0,52	0,6	neutral	0,24	disease	0,79	disease	0,62	disease	0,66	3	neutral	0,63	deleterious	0,67	neutral	-3	neutral	0,21	medium_impact	0,75	medium_impact	0,07	medium_impact	0,99	0,49	0,8	56,12	10,37	P	0,63	P	0,08	disease_causing	0,75	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10580	10580	A	T	MI.15922	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	111	37	M	I	atA/atT	5,83	1	0	benign	0,02	neutral	0,36	neutral	1,86	neutral	-0,69	deleterious	-3,5	medium_impact	2,54	neutral	0,89	neutral	0,74	neutral	1,37	12,65	0,52	0,6	neutral	0,24	disease	0,79	disease	0,62	disease	0,66	3	neutral	0,63	deleterious	0,67	neutral	-3	neutral	0,21	medium_impact	0,75	medium_impact	0,07	medium_impact	0,99	0,49	0,8	56,12	10,37	P	0,63	P	0,08	disease_causing	0,75	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10581	10581	C	G	MI.15923	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	112	38	L	V	Cta/Gta	1,21	0,57	0	possibly_damaging	0,68	neutral	0,22	neutral	1,68	neutral	-1,99	deleterious	-2,75	medium_impact	3,26	damaging	0,58	neutral	0,45	neutral	1,61	13,93	0,53	0,6	disease	0,62	neutral	0,5	disease	0,6	disease	0,6	2	neutral	0,82	neutral	0,27	NA	0	deleterious	0,68	low_impact	-1,1	medium_impact	-0,1	medium_impact	1,59	0,68	0,85	48,98	10,58	N	0,43	N	0,43	disease_causing	0,97	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10581	10581	C	A	MI.15924	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	112	38	L	M	Cta/Ata	1,21	0,57	0	possibly_damaging	0,68	neutral	0,14	neutral	1,64	deleterious	-3,74	neutral	-1,88	medium_impact	2,94	neutral	0,67	neutral	0,62	neutral	1,71	14,46	0,4	0,5	disease	0,69	disease	0,53	disease	0,59	disease	0,58	2	neutral	0,88	neutral	0,23	NA	0	deleterious	0,47	low_impact	-1,1	medium_impact	-0,23	medium_impact	1,33	0,62	0,8	48,98	10,58	N	0,39	N	0,08	disease_causing	0,97	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10582	10582	T	A	MI.15925	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	113	38	L	Q	cTa/cAa	-4,78	0	0	probably_damaging	0,98	deleterious	0,02	neutral	1,65	deleterious	-4,15	deleterious	-5,74	high_impact	4,68	damaging	0,55	neutral	0,33	deleterious	4,09	23,7	0,31	0,45	disease	0,9	disease	0,76	disease	0,67	disease	0,79	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-2,35	medium_impact	-0,73	high_impact	2,78	0,66	0,8	48,98	10,58	N	0,47	N	0,92	disease_causing	0,64	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10582	10582	T	C	MI.15926	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	113	38	L	P	cTa/cCa	-4,78	0	0	probably_damaging	0,99	deleterious	0,01	neutral	1,62	deleterious	-5,09	deleterious	-6,7	high_impact	4,68	damaging	0,43	neutral	0,32	deleterious	3,83	23,4	0,28	0,45	disease	0,92	disease	0,79	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,63	medium_impact	-0,9	high_impact	2,78	0,61	0,8	48,98	10,58	P	0,61	P	0,96	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10582	10582	T	G	MI.15927	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	113	38	L	R	cTa/cGa	-4,78	0	0	probably_damaging	0,98	deleterious	0,02	neutral	1,64	deleterious	-4,09	deleterious	-5,74	high_impact	4,68	damaging	0,5	damaging	0,25	deleterious	3,96	23,6	0,24	0,45	disease	0,89	disease	0,85	disease	0,77	disease	0,85	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,88	low_impact	-2,35	medium_impact	-0,73	high_impact	2,78	0,58	0,8	48,98	10,58	P	0,57	P	0,94	disease_causing	0,69	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10584	10584	T	G	MI.15928	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	115	39	S	A	Tcg/Gcg	-2,24	0	0	possibly_damaging	0,64	neutral	0,51	neutral	2,12	neutral	0,44	neutral	-2,44	medium_impact	2,04	neutral	0,78	neutral	0,92	deleterious	0,54	7,71	0,59	0,65	neutral	0,29	neutral	0,34	neutral	0,36	neutral	0,43	1	neutral	0,62	neutral	0,44	NA	0	deleterious	0,45	low_impact	-1,03	medium_impact	0,22	medium_impact	0,57	0,72	0,85	53,06	11,18	N	0,36	N	0,42	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10584	10584	T	C	MI.15929	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	115	39	S	P	Tcg/Ccg	-2,24	0	0	benign	0,08	neutral	0,2	neutral	1,62	deleterious	-4,97	deleterious	-4,2	high_impact	4,25	neutral	0,77	neutral	0,46	deleterious	1,9	15,6	0,24	0,45	disease	0,68	disease	0,87	disease	0,68	disease	0,76	5	neutral	0,78	deleterious	0,56	neutral	-2	neutral	0,31	medium_impact	0,17	medium_impact	-0,12	high_impact	2,42	0,59	0,8	53,06	11,18	N	0,44	N	0,95	polymorphism	1	0,27	.	.	.	.	.	.	COSM1155497	.	.	.	.	.	.	.	.
chrM	8435	8435	A	T	MI.1593	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	70	24	T	S	Acc/Tcc	-4,5	0	0,01	benign	0,22	neutral	0,36	neutral	2,11	deleterious	-3,88	neutral	-1,07	low_impact	1,71	neutral	0,99	neutral	0,62	neutral	1,36	12,56	0,48138703	0,85	neutral	0,32	neutral	0,16	disease	0,51	neutral	0,2	6	neutral	0,57	deleterious	0,57	neutral	-6	neutral	0,25	medium_impact	-0,23	medium_impact	0,15	medium_impact	0,37	0,76	0,85	NA	NA	N	0,51	P	0,4	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10584	10584	T	A	MI.15930	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	115	39	S	T	Tcg/Acg	-2,24	0	0	benign	0,12	neutral	0,39	neutral	1,7	neutral	-2,22	neutral	-2,43	medium_impact	2,34	neutral	0,81	neutral	0,87	neutral	1,66	14,19	0,53	0,6	neutral	0,45	neutral	0,39	neutral	0,38	neutral	0,43	1	neutral	0,55	deleterious	0,64	neutral	-3	neutral	0,21	medium_impact	-0,01	medium_impact	0,1	medium_impact	0,82	0,83	0,9	53,06	11,18	N	0,41	N	0,69	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10585	10585	C	T	MI.15931	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	116	39	S	L	tCg/tTg	0,52	0,3	0	possibly_damaging	0,83	neutral	0,65	neutral	1,63	deleterious	-4,14	deleterious	-5,35	medium_impact	3,15	neutral	0,75	neutral	0,6	deleterious	4,17	23,8	0,38	0,5	neutral	0,49	disease	0,85	disease	0,52	disease	0,71	4	neutral	0,8	neutral	0,41	NA	0	deleterious	0,63	low_impact	-1,43	medium_impact	0,36	medium_impact	1,5	0,84	0,9	53,06	11,18	N	0,35	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10585	10585	C	G	MI.15932	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	116	39	S	W	tCg/tGg	0,52	0,3	0	probably_damaging	0,98	neutral	0,18	neutral	1,61	deleterious	-7,44	deleterious	-6,39	high_impact	4,25	neutral	0,65	neutral	0,32	deleterious	4,18	23,8	0,23	0,45	disease	0,89	disease	0,88	disease	0,61	disease	0,79	6	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-2,35	medium_impact	-0,16	high_impact	2,42	0,41	0,8	53,06	11,18	N	0,4	N	0,99	disease_causing	0,62	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10587	10587	C	G	MI.15933	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	118	40	L	V	Ctg/Gtg	-20	0	0	probably_damaging	1	neutral	0,19	neutral	2,01	neutral	0,04	neutral	-2,03	medium_impact	1,99	neutral	0,76	damaging	0,28	deleterious	3,21	22,7	0,49	0,55	neutral	0,39	neutral	0,47	neutral	0,44	neutral	0,47	1	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,71	low_impact	-3,55	medium_impact	-0,14	medium_impact	0,53	0,62	0,8	50	8,6	N	0,33	N	0,67	polymorphism	1	0,03	rs879216682	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10587	10587	C	A	MI.15934	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	118	40	L	M	Ctg/Atg	-20	0	0	probably_damaging	1	neutral	0,19	neutral	1,71	neutral	-2,88	neutral	-0,75	medium_impact	2,1	neutral	0,79	neutral	0,88	deleterious	2,3	18,15	0,39	0,5	neutral	0,39	neutral	0,24	neutral	0,42	neutral	0,43	1	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,68	low_impact	-3,55	medium_impact	-0,14	medium_impact	0,62	0,66	0,8	50	8,6	N	0,4	N	0,62	polymorphism	1	0,02	rs879216682	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10588	10588	T	A	MI.15935	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	119	40	L	Q	cTg/cAg	-2,24	0	0	probably_damaging	1	deleterious	0,02	neutral	1,68	deleterious	-4,44	deleterious	-4,68	high_impact	3,92	neutral	0,71	damaging	0,07	deleterious	4,01	23,6	0,13	0,4	disease	0,71	disease	0,74	disease	0,62	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,55	medium_impact	-0,73	high_impact	2,15	0,73	0,85	50	8,6	N	0,31	N	0,96	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10588	10588	T	G	MI.15936	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	119	40	L	R	cTg/cGg	-2,24	0	0	probably_damaging	1	deleterious	0,02	neutral	1,68	deleterious	-4,26	deleterious	-4,92	high_impact	4,26	neutral	0,63	damaging	0,04	deleterious	4,05	23,7	0,1	0,4	disease	0,7	disease	0,86	disease	0,73	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-3,55	medium_impact	-0,73	high_impact	2,43	0,56	0,8	50	8,6	N	0,37	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10588	10588	T	C	MI.15937	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	119	40	L	P	cTg/cCg	-2,24	0	0	probably_damaging	1	deleterious	0,01	neutral	1,68	deleterious	-4,84	deleterious	-5,78	high_impact	4,26	neutral	0,68	damaging	0,08	deleterious	3,78	23,4	0,12	0,4	disease	0,79	disease	0,82	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,55	medium_impact	-0,9	high_impact	2,43	0,66	0,8	50	8,6	N	0,33	N	0,95	polymorphism	0,69	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10590	10590	T	A	MI.15938	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	121	41	F	I	Ttc/Atc	-3,17	0	0	possibly_damaging	0,75	neutral	0,45	neutral	1,87	neutral	-1,18	deleterious	-5,71	high_impact	3,51	neutral	0,77	neutral	0,54	deleterious	4,19	23,8	0,39	0,5	neutral	0,48	disease	0,9	disease	0,7	disease	0,8	6	neutral	0,74	neutral	0,35	deleterious	1	deleterious	0,64	low_impact	-1,24	medium_impact	0,16	medium_impact	1,8	0,62	0,8	55,1	11,99	N	0,41	N	0,66	polymorphism	0,95	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10590	10590	T	C	MI.15939	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	121	41	F	L	Ttc/Ctc	-3,17	0	0	benign	0,12	neutral	0,84	neutral	1,9	neutral	-0,81	deleterious	-5,71	medium_impact	2,98	neutral	0,78	neutral	0,56	deleterious	2,16	17,22	0,58	0,65	neutral	0,3	disease	0,86	disease	0,65	disease	0,7	4	neutral	0,07	deleterious	0,86	neutral	-3	neutral	0,23	medium_impact	-0,01	medium_impact	0,61	medium_impact	1,36	0,59	0,8	55,1	11,99	N	0,27	N	0,89	polymorphism	0,95	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8436	8436	C	A	MI.1594	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	71	24	T	N	aCc/aAc	-2,88	0	0	possibly_damaging	0,54	neutral	0,39	neutral	1,95	deleterious	-5,08	neutral	-2,07	medium_impact	2,51	neutral	0,99	neutral	0,62	deleterious	3,18	22,7	0,48647755	0,85	neutral	0,49	neutral	0,31	disease	0,57	neutral	0,18	7	neutral	0,61	neutral	0,43	NA	0	deleterious	0,58	medium_impact	-0,82	medium_impact	0,18	medium_impact	1,05	0,68	0,85	NA	NA	N	0,49	N	0,51	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10590	10590	T	G	MI.15940	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	121	41	F	V	Ttc/Gtc	-3,17	0	0	possibly_damaging	0,83	neutral	0,34	neutral	1,88	neutral	-1,05	deleterious	-6,64	high_impact	3,51	neutral	0,7	neutral	0,45	deleterious	3,9	23,5	0,39	0,5	disease	0,52	disease	0,9	disease	0,71	disease	0,8	6	neutral	0,85	neutral	0,26	deleterious	1	deleterious	0,67	low_impact	-1,43	medium_impact	0,05	medium_impact	1,8	0,62	0,8	55,1	11,99	N	0,39	N	0,9	polymorphism	0,9	0,11	rs28532736	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10591	10591	T	G	MI.15941	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	122	41	F	C	tTc/tGc	5,83	1	0	probably_damaging	0,98	neutral	0,05	neutral	1,78	deleterious	-4,15	deleterious	-7,64	high_impact	4,55	neutral	0,65	neutral	0,42	deleterious	4,03	23,7	0,37	0,5	disease	0,87	disease	0,91	disease	0,7	disease	0,81	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,81	low_impact	-2,35	medium_impact	-0,5	high_impact	2,68	0,28	0,8	55,1	11,99	P	0,67	P	0,96	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	T10591G	LHON	-	+	Reported	1
chrM	10591	10591	T	C	MI.15942	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	122	41	F	S	tTc/tCc	5,83	1	0	probably_damaging	0,96	neutral	0,4	neutral	1,82	neutral	-2,14	deleterious	-7,57	high_impact	3,75	neutral	0,72	neutral	0,54	deleterious	4,17	23,8	0,38	0,5	disease	0,77	disease	0,89	disease	0,68	disease	0,76	5	neutral	0,96	neutral	0,22	deleterious	2	deleterious	0,81	low_impact	-2,07	medium_impact	0,11	high_impact	2,01	0,4	0,8	55,1	11,99	P	0,68	P	0,97	disease_causing	0,99	0,11	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	10591	10591	T	A	MI.15943	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	122	41	F	Y	tTc/tAc	5,83	1	0	benign	0,17	neutral	0,59	neutral	1,83	neutral	-1,97	deleterious	-2,66	medium_impact	2,17	neutral	0,79	neutral	0,7	deleterious	2,63	20,4	0,41	0,5	disease	0,52	disease	0,61	disease	0,58	neutral	0,47	1	neutral	0,3	deleterious	0,71	neutral	-3	deleterious	0,7	medium_impact	-0,17	medium_impact	0,3	medium_impact	0,68	0,61	0,8	55,1	11,99	P	0,57	P	0,85	disease_causing	0,96	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10592	10592	C	A	MI.15944	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	123	41	F	L	ttC/ttA	2,83	0,99	0	benign	0,12	neutral	0,84	neutral	1,9	neutral	-0,81	deleterious	-5,71	medium_impact	2,98	neutral	0,78	neutral	0,56	deleterious	2,83	21,5	0,58	0,65	neutral	0,3	disease	0,86	disease	0,65	disease	0,7	4	neutral	0,07	deleterious	0,86	neutral	-3	neutral	0,23	medium_impact	-0,01	medium_impact	0,61	medium_impact	1,36	0,59	0,8	55,1	11,99	N	0,42	N	0,89	disease_causing	0,93	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10592	10592	C	G	MI.15945	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	123	41	F	L	ttC/ttG	2,83	0,99	0	benign	0,12	neutral	0,84	neutral	1,9	neutral	-0,81	deleterious	-5,71	medium_impact	2,98	neutral	0,78	neutral	0,56	deleterious	2,49	19,41	0,58	0,65	neutral	0,3	disease	0,86	disease	0,65	disease	0,7	4	neutral	0,07	deleterious	0,86	neutral	-3	neutral	0,23	medium_impact	-0,01	medium_impact	0,61	medium_impact	1,36	0,59	0,8	55,1	11,99	N	0,42	N	0,89	disease_causing	0,93	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10593	10593	A	C	MI.15946	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	124	42	I	L	Att/Ctt	-4,78	0	0	benign	0,26	neutral	1	neutral	2,39	neutral	1,61	neutral	-1,35	low_impact	1,29	neutral	0,78	neutral	0,76	deleterious	0,82	9,6	0,38	0,5	neutral	0,19	disease	0,53	neutral	0,3	neutral	0,44	1	neutral	0,26	deleterious	0,87	neutral	-6	neutral	0,21	medium_impact	-0,39	high_impact	1,88	medium_impact	-0,06	0,41	0,8	15,31	9,67	N	0,29	N	0,6	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10593	10593	A	T	MI.15947	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	124	42	I	F	Att/Ttt	-4,78	0	0	possibly_damaging	0,87	neutral	0,64	neutral	1,85	neutral	-1,51	deleterious	-3,18	low_impact	1,5	neutral	0,69	neutral	0,42	deleterious	3,44	23	0,41	0,5	neutral	0,18	disease	0,69	neutral	0,38	disease	0,53	1	neutral	0,85	neutral	0,39	neutral	-3	deleterious	0,62	low_impact	-1,56	medium_impact	0,35	medium_impact	0,12	0,56	0,8	15,31	9,67	N	0,3	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10593	10593	A	G	MI.15948	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	124	42	I	V	Att/Gtt	-4,78	0	0	possibly_damaging	0,53	neutral	0,48	neutral	1,9	neutral	-0,87	neutral	-0,33	low_impact	0,82	neutral	0,85	neutral	0,99	neutral	-0,12	1,58	0,59	0,65	neutral	0,16	neutral	0,27	neutral	0,38	neutral	0,43	1	neutral	0,53	deleterious	0,48	neutral	-3	neutral	0,35	medium_impact	-0,85	medium_impact	0,19	medium_impact	-0,45	0,38	0,8	15,31	9,67	N	0,32	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10594	10594	T	C	MI.15949	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	125	42	I	T	aTt/aCt	-1,55	0	0	benign	0,13	neutral	0,18	neutral	1,83	neutral	-2	deleterious	-2,92	medium_impact	2,1	neutral	0,84	neutral	0,97	deleterious	2,85	21,6	0,53	0,6	neutral	0,38	disease	0,61	neutral	0,41	neutral	0,48	0	neutral	0,79	deleterious	0,53	neutral	-3	deleterious	0,57	medium_impact	-0,05	medium_impact	-0,16	medium_impact	0,62	0,64	0,8	15,31	9,67	N	0,45	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	COSM1138224	.	.	.	.	.	.	.	.
chrM	8436	8436	C	T	MI.1595	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	71	24	T	I	aCc/aTc	-2,88	0	0	benign	0	neutral	0,67	neutral	2,19	deleterious	-3,48	neutral	0,58	neutral_impact	0,18	neutral	1	neutral	0,87	deleterious	0,26	5,29	0,56070775	0,85	neutral	0,28	neutral	0,3	neutral	0,37	neutral	0,14	7	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,17	high_impact	2,09	medium_impact	0,47	medium_impact	-0,94	0,64	0,85	NA	NA	N	0,31	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10594	10594	T	G	MI.15950	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	125	42	I	S	aTt/aGt	-1,55	0	0	possibly_damaging	0,76	neutral	0,61	neutral	1,82	neutral	-2,12	deleterious	-4,26	medium_impact	2,52	neutral	0,77	neutral	0,48	deleterious	3,83	23,4	0,38	0,5	neutral	0,44	disease	0,8	disease	0,52	disease	0,67	3	neutral	0,72	neutral	0,43	NA	0	deleterious	0,57	low_impact	-1,26	medium_impact	0,32	medium_impact	0,97	0,52	0,8	15,31	9,67	N	0,22	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10594	10594	T	A	MI.15951	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	125	42	I	N	aTt/aAt	-1,55	0	0	benign	0,11	neutral	0,11	neutral	1,78	deleterious	-3,93	deleterious	-5,26	high_impact	3,85	neutral	0,74	neutral	0,36	deleterious	2,44	19,06	0,3	0,45	disease	0,6	disease	0,79	disease	0,62	disease	0,71	4	neutral	0,88	deleterious	0,5	neutral	-2	neutral	0,26	medium_impact	0,03	medium_impact	-0,29	high_impact	2,09	0,62	0,8	15,31	9,67	N	0,41	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10595	10595	T	G	MI.15952	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	126	42	I	M	atT/atG	1,21	0	0	benign	0,4	neutral	0,34	neutral	1,83	neutral	-1,85	neutral	-1,65	medium_impact	1,96	neutral	0,85	neutral	0,82	deleterious	0,38	6,43	0,44	0,55	neutral	0,42	disease	0,51	neutral	0,32	neutral	0,46	1	neutral	0,6	deleterious	0,47	neutral	-3	neutral	0,26	medium_impact	-0,64	medium_impact	0,05	medium_impact	0,51	0,58	0,8	15,31	9,67	N	0,37	N	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10595	10595	T	A	MI.15953	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	126	42	I	M	atT/atA	1,21	0	0	benign	0,4	neutral	0,34	neutral	1,83	neutral	-1,85	neutral	-1,65	medium_impact	1,96	neutral	0,85	neutral	0,82	deleterious	0,7	8,83	0,44	0,55	neutral	0,42	disease	0,51	neutral	0,32	neutral	0,46	1	neutral	0,6	deleterious	0,47	neutral	-3	neutral	0,26	medium_impact	-0,64	medium_impact	0,05	medium_impact	0,51	0,58	0,8	15,31	9,67	N	0,36	N	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10596	10596	A	T	MI.15954	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	127	43	M	L	Ata/Tta	-9,62	0	0	benign	0,01	neutral	0,94	neutral	2,16	neutral	1,51	neutral	0,23	neutral_impact	0,2	neutral	0,79	neutral	0,97	neutral	-1,12	0,01	0,5	0,6	neutral	0,4	neutral	0,46	neutral	0,31	neutral	0,48	1	neutral	0,04	deleterious	0,97	neutral	-6	neutral	0,18	medium_impact	1,03	medium_impact	0,87	medium_impact	-0,97	0,58	0,8	22,45	8,75	N	0,33	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10596	10596	A	C	MI.15955	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	127	43	M	L	Ata/Cta	-9,62	0	0	benign	0,01	neutral	0,94	neutral	2,16	neutral	1,51	neutral	0,23	neutral_impact	0,2	neutral	0,79	neutral	0,97	neutral	-1,19	0,01	0,5	0,6	neutral	0,4	neutral	0,46	neutral	0,31	neutral	0,48	1	neutral	0,04	deleterious	0,97	neutral	-6	neutral	0,18	medium_impact	1,03	medium_impact	0,87	medium_impact	-0,97	0,58	0,8	22,45	8,75	N	0,33	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10596	10596	A	G	MI.15956	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	127	43	M	V	Ata/Gta	-9,62	0	0	benign	0,02	neutral	0,53	neutral	2,03	neutral	0,36	neutral	-1,5	medium_impact	2,53	neutral	0,74	neutral	0,72	neutral	-0,74	0,06	0,58	0,65	neutral	0,39	disease	0,57	neutral	0,48	disease	0,54	1	neutral	0,45	deleterious	0,76	neutral	-3	neutral	0,2	medium_impact	0,75	medium_impact	0,24	medium_impact	0,98	0,52	0,8	22,45	8,75	N	0,36	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10597	10597	T	C	MI.15957	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	128	43	M	T	aTa/aCa	-3,4	0	0	benign	0,01	neutral	0,38	neutral	1,97	neutral	-0,46	deleterious	-3,49	medium_impact	2,53	neutral	0,83	neutral	0,86	neutral	-0,54	0,18	0,56	0,6	neutral	0,39	disease	0,51	neutral	0,4	neutral	0,46	1	neutral	0,61	deleterious	0,69	neutral	-3	neutral	0,18	medium_impact	1,03	medium_impact	0,09	medium_impact	0,98	0,46	0,8	22,45	8,75	N	0,4	N	0,66	polymorphism	1	0,07	.	.	.	.	.	.	COSM1155498	.	.	.	.	.	.	.	.
chrM	10597	10597	T	A	MI.15958	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	128	43	M	K	aTa/aAa	-3,4	0	0	benign	0,34	neutral	0,27	neutral	1,93	neutral	-2,22	deleterious	-4,33	high_impact	3,68	neutral	0,73	neutral	0,38	neutral	0,95	10,37	0,29	0,45	neutral	0,45	disease	0,8	disease	0,6	disease	0,77	5	neutral	0,68	neutral	0,47	neutral	-2	deleterious	0,44	medium_impact	-0,54	medium_impact	-0,03	medium_impact	1,95	0,53	0,8	22,45	8,75	N	0,41	N	0,87	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10598	10598	A	T	MI.15959	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	129	43	M	I	atA/atT	2,37	0,02	0	benign	0,01	neutral	0,63	neutral	2,02	neutral	0,31	neutral	-0,83	low_impact	1,5	neutral	0,8	neutral	0,94	neutral	-0,07	1,95	0,48	0,55	neutral	0,46	disease	0,58	neutral	0,35	neutral	0,48	1	neutral	0,36	deleterious	0,81	neutral	-6	neutral	0,21	medium_impact	1,03	medium_impact	0,34	medium_impact	0,12	0,66	0,8	22,45	8,75	N	0,28	N	0,1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8436	8436	C	G	MI.1596	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	71	24	T	S	aCc/aGc	-2,88	0	0	benign	0,22	neutral	0,36	neutral	2,11	deleterious	-3,88	neutral	-1,07	low_impact	1,71	neutral	0,99	neutral	0,62	neutral	1,6	13,83	0,48138703	0,85	neutral	0,32	neutral	0,16	disease	0,51	neutral	0,2	6	neutral	0,57	deleterious	0,57	neutral	-6	neutral	0,25	medium_impact	-0,23	medium_impact	0,15	medium_impact	0,37	0,76	0,85	NA	NA	N	0,51	P	0,4	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10598	10598	A	C	MI.15960	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	129	43	M	I	atA/atC	2,37	0,02	0	benign	0,01	neutral	0,63	neutral	2,02	neutral	0,31	neutral	-0,83	low_impact	1,5	neutral	0,8	neutral	0,94	neutral	-0,17	1,29	0,48	0,55	neutral	0,46	disease	0,58	neutral	0,35	neutral	0,48	1	neutral	0,36	deleterious	0,81	neutral	-6	neutral	0,21	medium_impact	1,03	medium_impact	0,34	medium_impact	0,12	0,66	0,8	22,45	8,75	N	0,28	N	0,1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10599	10599	G	T	MI.15961	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	130	44	A	S	Gct/Tct	-2,71	0	0	benign	0	neutral	0,2	neutral	1,97	neutral	-0,7	neutral	0,22	neutral_impact	0,07	neutral	0,86	neutral	0,93	deleterious	0,13	3,88	0,4	0,5	neutral	0,17	neutral	0,24	neutral	0,24	neutral	0,44	1	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,1	medium_impact	1,95	medium_impact	-0,12	low_impact	-1,08	0,74	0,85	25,51	23,13	N	0,45	N	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10599	10599	G	A	MI.15962	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	130	44	A	T	Gct/Act	-2,71	0	0	benign	0,01	neutral	0,08	neutral	2	neutral	0,02	neutral	-0,16	neutral_impact	-0,58	neutral	0,85	neutral	0,98	deleterious	0,74	9,08	0,4	0,5	neutral	0,13	neutral	0,21	neutral	0,25	neutral	0,37	3	neutral	0,92	deleterious	0,54	neutral	-6	neutral	0,09	medium_impact	1,03	medium_impact	-0,38	low_impact	-1,62	0,62	0,8	25,51	23,13	N	0,43	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10599	10599	G	C	MI.15963	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	130	44	A	P	Gct/Cct	-2,71	0	0	benign	0,42	deleterious	0,02	neutral	1,94	neutral	-2,52	neutral	-2,23	low_impact	1,9	neutral	0,73	neutral	0,42	deleterious	1,88	15,45	0,19	0,45	neutral	0,35	disease	0,73	disease	0,62	disease	0,76	5	neutral	0,98	neutral	0,3	neutral	-2	neutral	0,29	medium_impact	-0,68	medium_impact	-0,73	medium_impact	0,46	0,77	0,85	25,51	23,13	N	0,32	N	0,79	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10600	10600	C	A	MI.15964	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	131	44	A	D	gCt/gAt	-4,55	0	0	benign	0,18	deleterious	0,02	neutral	1,93	deleterious	-3,16	neutral	-1,95	low_impact	1,9	neutral	0,71	neutral	0,37	deleterious	2,56	19,85	0,22	0,45	neutral	0,46	disease	0,69	disease	0,62	disease	0,75	5	neutral	0,98	neutral	0,42	neutral	-2	neutral	0,23	medium_impact	-0,2	medium_impact	-0,73	medium_impact	0,46	0,66	0,8	25,51	23,13	N	0,34	N	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10600	10600	C	G	MI.15965	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	131	44	A	G	gCt/gGt	-4,55	0	0	benign	0,01	neutral	0,08	neutral	1,95	neutral	-1,75	neutral	-1,4	neutral_impact	0,66	neutral	0,86	neutral	0,9	deleterious	0,78	9,34	0,25	0,45	neutral	0,36	neutral	0,37	neutral	0,46	neutral	0,47	1	neutral	0,92	deleterious	0,54	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	-0,38	medium_impact	-0,59	0,73	0,85	25,51	23,13	N	0,47	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10600	10600	C	T	MI.15966	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	131	44	A	V	gCt/gTt	-4,55	0	0	benign	0,04	neutral	0,24	neutral	2,07	neutral	0,94	neutral	-1,06	neutral_impact	-0,32	neutral	0,82	neutral	0,9	neutral	1,16	11,51	0,48	0,55	neutral	0,14	neutral	0,37	neutral	0,29	neutral	0,46	1	neutral	0,74	deleterious	0,6	neutral	-6	neutral	0,11	medium_impact	0,46	medium_impact	-0,07	low_impact	-1,41	0,66	0,8	25,51	23,13	N	0,37	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10602	10602	A	G	MI.15967	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	133	45	T	A	Act/Gct	-13,08	0	0	benign	0,03	neutral	0,54	neutral	2,04	neutral	0,48	neutral	-1,71	neutral_impact	0,7	neutral	0,85	neutral	0,99	neutral	-0,32	0,6	0,61	0,65	neutral	0,13	neutral	0,29	neutral	0,33	neutral	0,42	2	neutral	0,42	deleterious	0,76	neutral	-6	neutral	0,12	medium_impact	0,58	medium_impact	0,25	medium_impact	-0,55	0,45	0,8	17,35	7,83	N	0,34	N	0,05	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10602	10602	A	T	MI.15968	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	133	45	T	S	Act/Tct	-13,08	0	0	benign	0,08	neutral	0,74	neutral	2,01	neutral	0,21	neutral	-0,67	neutral_impact	0,28	neutral	0,81	neutral	0,99	neutral	-1,07	0,01	0,59	0,65	neutral	0,1	neutral	0,11	neutral	0,28	neutral	0,23	5	neutral	0,16	deleterious	0,83	neutral	-6	neutral	0,34	medium_impact	0,17	medium_impact	0,46	medium_impact	-0,9	0,59	0,8	17,35	7,83	N	0,37	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10602	10602	A	C	MI.15969	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	133	45	T	P	Act/Cct	-13,08	0	0	possibly_damaging	0,89	neutral	0,21	neutral	1,92	neutral	-2,57	deleterious	-3,54	medium_impact	3,04	neutral	0,64	neutral	0,39	deleterious	3,3	22,9	0,22	0,45	neutral	0,44	disease	0,86	disease	0,64	disease	0,79	6	neutral	0,93	neutral	0,16	NA	0	deleterious	0,7	low_impact	-1,64	medium_impact	-0,11	medium_impact	1,41	0,58	0,8	17,35	7,83	N	0,41	N	0,73	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8438	8438	C	A	MI.1597	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	73	25	Q	K	Caa/Aaa	-8,2	0	0	probably_damaging	0,94	neutral	0,29	neutral	1,58	deleterious	-4,21	deleterious	-3,99	medium_impact	2,96	neutral	0,99	neutral	0,3	deleterious	3,85	23,4	0,37595543	0,85	disease	0,59	disease	0,58	disease	0,78	disease	0,68	4	neutral	0,95	neutral	0,18	deleterious	1	deleterious	0,73	low_impact	-1,89	medium_impact	0,07	medium_impact	1,44	0,57	0,85	5,88	7,45	N	0,48	N	0,85	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10603	10603	C	T	MI.15970	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	134	45	T	I	aCt/aTt	-7,55	0	0	possibly_damaging	0,75	neutral	0,45	neutral	2,11	neutral	1,14	deleterious	-3,27	low_impact	1,75	neutral	0,84	neutral	0,68	deleterious	2,53	19,63	0,49	0,55	neutral	0,18	disease	0,76	neutral	0,39	disease	0,62	2	neutral	0,74	neutral	0,35	neutral	-3	deleterious	0,58	low_impact	-1,24	medium_impact	0,16	medium_impact	0,33	0,74	0,85	17,35	7,83	N	0,29	N	0,64	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10603	10603	C	G	MI.15971	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	134	45	T	S	aCt/aGt	-7,55	0	0	benign	0,08	neutral	0,74	neutral	2,01	neutral	0,21	neutral	-0,67	neutral_impact	0,28	neutral	0,81	neutral	0,99	neutral	-0,89	0,03	0,59	0,65	neutral	0,1	neutral	0,11	neutral	0,28	neutral	0,23	5	neutral	0,16	deleterious	0,83	neutral	-6	neutral	0,34	medium_impact	0,17	medium_impact	0,46	medium_impact	-0,9	0,59	0,8	17,35	7,83	N	0,37	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10603	10603	C	A	MI.15972	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	134	45	T	N	aCt/aAt	-7,55	0	0	possibly_damaging	0,75	neutral	0,25	neutral	1,92	neutral	-2,39	deleterious	-2,5	medium_impact	2,24	neutral	0,74	neutral	0,49	deleterious	3,43	23	0,55	0,6	neutral	0,35	disease	0,66	neutral	0,5	disease	0,53	1	neutral	0,83	neutral	0,25	NA	0	deleterious	0,64	low_impact	-1,24	medium_impact	-0,06	medium_impact	0,74	0,76	0,85	17,35	7,83	N	0,38	N	0,52	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10605	10605	C	T	MI.15973	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	136	46	L	F	Ctc/Ttc	-14,24	0	0	benign	0,17	neutral	0,61	neutral	1,78	neutral	-2,25	deleterious	-2,61	low_impact	1,74	neutral	0,81	neutral	0,71	deleterious	2	16,21	0,52	0,6	disease	0,52	neutral	0,41	neutral	0,42	neutral	0,37	3	neutral	0,28	deleterious	0,72	neutral	-6	neutral	0,18	medium_impact	-0,17	medium_impact	0,32	medium_impact	0,32	0,74	0,85	19,39	13,62	N	0,28	N	0,52	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10605	10605	C	G	MI.15974	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	136	46	L	V	Ctc/Gtc	-14,24	0	0	benign	0,08	neutral	0,18	neutral	1,87	neutral	-0,9	neutral	-0,9	low_impact	1,26	neutral	0,85	neutral	0,98	deleterious	0,38	6,47	0,55	0,6	neutral	0,18	neutral	0,29	neutral	0,39	neutral	0,44	1	neutral	0,8	deleterious	0,55	neutral	-6	neutral	0,11	medium_impact	0,17	medium_impact	-0,16	medium_impact	-0,08	0,72	0,85	19,39	13,62	N	0,43	N	0,07	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10605	10605	C	A	MI.15975	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	136	46	L	I	Ctc/Atc	-14,24	0	0	benign	0,08	neutral	0,42	neutral	1,87	neutral	-0,97	neutral	-0,4	neutral_impact	0,5	neutral	0,81	neutral	1	deleterious	0,59	8,1	0,54	0,6	neutral	0,17	neutral	0,26	neutral	0,32	neutral	0,44	1	neutral	0,53	deleterious	0,67	neutral	-6	neutral	0,12	medium_impact	0,17	medium_impact	0,13	medium_impact	-0,72	0,76	0,85	19,39	13,62	N	0,36	N	0,31	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10606	10606	T	A	MI.15976	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	137	46	L	H	cTc/cAc	-3,63	0	0	probably_damaging	0,98	neutral	0,1	neutral	1,74	deleterious	-3,89	deleterious	-4,9	high_impact	3,65	neutral	0,82	neutral	0,54	deleterious	3,96	23,6	0,3	0,45	disease	0,79	disease	0,73	disease	0,71	disease	0,76	5	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,77	low_impact	-2,35	medium_impact	-0,32	medium_impact	1,92	0,64	0,8	19,39	13,62	N	0,38	N	0,87	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10606	10606	T	G	MI.15977	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	137	46	L	R	cTc/cGc	-3,63	0	0	probably_damaging	0,93	neutral	0,06	neutral	1,74	deleterious	-3,89	deleterious	-4,3	high_impact	3,65	neutral	0,71	neutral	0,29	deleterious	4,07	23,7	0,27	0,45	disease	0,72	disease	0,83	disease	0,74	disease	0,8	6	deleterious	0,98	neutral	0,07	deleterious	2	deleterious	0,77	low_impact	-1,83	medium_impact	-0,45	medium_impact	1,92	0,71	0,85	19,39	13,62	N	0,37	N	0,95	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10606	10606	T	C	MI.15978	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	137	46	L	P	cTc/cCc	-3,63	0	0	probably_damaging	0,95	neutral	0,07	neutral	1,73	deleterious	-3,99	deleterious	-4,8	medium_impact	3,31	neutral	0,62	damaging	0,28	deleterious	3,77	23,4	0,25	0,45	disease	0,78	disease	0,83	disease	0,75	disease	0,8	6	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,79	low_impact	-1,97	medium_impact	-0,41	medium_impact	1,64	0,73	0,85	19,39	13,62	N	0,34	N	0,98	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10608	10608	A	C	MI.15979	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	139	47	M	L	Ata/Cta	-7,09	0	0,01	benign	0,01	neutral	0,72	neutral	2,1	neutral	1,16	neutral	0,53	neutral_impact	-1,01	neutral	0,77	neutral	0,97	deleterious	-0,04	2,21	0,56	0,6	neutral	0,11	neutral	0,4	neutral	0,34	neutral	0,43	1	neutral	0,26	deleterious	0,86	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,44	low_impact	-1,98	0,52	0,8	24,49	10,84	N	0,28	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8438	8438	C	G	MI.1598	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	73	25	Q	E	Caa/Gaa	-8,2	0	0	possibly_damaging	0,87	neutral	0,27	neutral	1,59	deleterious	-4,52	deleterious	-2,99	high_impact	3,86	neutral	0,98	neutral	0,38	deleterious	2,92	21,9	0,42653776	0,85	disease	0,64	neutral	0,44	disease	0,76	neutral	0,45	1	neutral	0,9	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-1,54	medium_impact	0,05	high_impact	2,21	0,57	0,85	5,88	7,45	N	0,51	P	0,73	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10608	10608	A	G	MI.15980	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	139	47	M	V	Ata/Gta	-7,09	0	0,01	benign	0,04	neutral	0,44	neutral	2,07	neutral	0,82	neutral	0,35	neutral_impact	0,26	neutral	0,82	neutral	0,88	neutral	-0,33	0,55	0,62	0,65	neutral	0,14	neutral	0,45	neutral	0,47	neutral	0,47	1	neutral	0,52	deleterious	0,7	neutral	-6	neutral	0,13	medium_impact	0,46	medium_impact	0,15	medium_impact	-0,92	0,48	0,8	24,49	10,84	N	0,29	N	0	polymorphism	1	0,01	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	10608	10608	A	T	MI.15981	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	139	47	M	L	Ata/Tta	-7,09	0	0,01	benign	0,01	neutral	0,72	neutral	2,1	neutral	1,16	neutral	0,53	neutral_impact	-1,01	neutral	0,77	neutral	0,97	deleterious	0,06	3,21	0,56	0,6	neutral	0,11	neutral	0,4	neutral	0,34	neutral	0,43	1	neutral	0,26	deleterious	0,86	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,44	low_impact	-1,98	0,52	0,8	24,49	10,84	N	0,27	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10609	10609	T	A	MI.15982	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	140	47	M	K	aTa/aAa	-0,63	0	0,12	benign	0,26	neutral	0,23	neutral	1,94	neutral	-1,63	deleterious	-2,78	low_impact	1,65	neutral	0,68	neutral	0,48	deleterious	2,17	17,34	0,29	0,45	neutral	0,27	disease	0,73	disease	0,58	disease	0,74	5	neutral	0,72	deleterious	0,49	neutral	-6	neutral	0,33	medium_impact	-0,39	medium_impact	-0,08	medium_impact	0,25	0,55	0,8	24,49	10,84	N	0,35	N	0,49	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10609	10609	T	C	MI.15983	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	140	47	M	T	aTa/aCa	-0,63	0	0,12	benign	0,01	neutral	0,43	neutral	2	neutral	-0,05	neutral	-0,76	neutral_impact	-1,09	neutral	0,85	neutral	0,98	neutral	-0,67	0,08	0,55	0,6	neutral	0,14	neutral	0,27	neutral	0,4	neutral	0,42	2	neutral	0,56	deleterious	0,71	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	0,14	low_impact	-2,05	0,34	0,8	24,49	10,84	N	0,25	N	0,03	polymorphism	1	0,01	rs200487531	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10610	10610	A	T	MI.15984	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	141	47	M	I	atA/atT	-0,17	0	0	benign	0,01	neutral	0,51	neutral	2,05	neutral	0,7	neutral	0,65	neutral_impact	-0,55	neutral	0,8	neutral	0,98	deleterious	0,13	3,93	0,52	0,6	neutral	0,11	neutral	0,46	neutral	0,37	neutral	0,44	1	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,22	low_impact	-1,6	0,54	0,8	24,49	10,84	N	0,3	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10610	10610	A	C	MI.15985	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	141	47	M	I	atA/atC	-0,17	0	0	benign	0,01	neutral	0,51	neutral	2,05	neutral	0,7	neutral	0,65	neutral_impact	-0,55	neutral	0,8	neutral	0,98	deleterious	0,1	3,6	0,52	0,6	neutral	0,11	neutral	0,46	neutral	0,37	neutral	0,44	1	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,22	low_impact	-1,6	0,54	0,8	24,49	10,84	N	0,29	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10611	10611	A	T	MI.15986	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	142	48	T	S	Acc/Tcc	-10,32	0	0	benign	0	neutral	0,7	neutral	2,14	neutral	1,54	neutral	-0,08	neutral_impact	-0,51	neutral	0,83	neutral	1	neutral	-1,18	0,01	0,72	0,75	neutral	0,15	neutral	0,18	neutral	0,34	neutral	0,32	4	neutral	0,29	deleterious	0,85	neutral	-6	neutral	0,11	medium_impact	1,95	medium_impact	0,41	low_impact	-1,57	0,78	0,85	33,67	21,31	N	0,37	N	0,01	polymorphism	1	0,01	rs386829106	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10611	10611	A	C	MI.15987	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	142	48	T	P	Acc/Ccc	-10,32	0	0	benign	0,2	neutral	0,27	neutral	1,97	neutral	-0,78	neutral	-2,14	low_impact	0,8	neutral	0,82	neutral	0,96	neutral	-0,17	1,24	0,24	0,45	neutral	0,18	disease	0,68	disease	0,51	neutral	0,47	1	neutral	0,68	deleterious	0,54	neutral	-6	neutral	0,32	medium_impact	-0,25	medium_impact	-0,03	medium_impact	-0,47	0,7	0,85	33,67	21,31	N	0,33	N	0,54	polymorphism	1	0,07	rs386829106	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10611	10611	A	G	MI.15988	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	142	48	T	A	Acc/Gcc	-10,32	0	0	benign	0	neutral	0,58	neutral	2,08	neutral	1,06	neutral	0,1	neutral_impact	0,4	neutral	0,9	neutral	0,97	neutral	-0,97	0,02	0,72	0,75	neutral	0,21	neutral	0,17	neutral	0,33	neutral	0,27	5	neutral	0,42	deleterious	0,79	neutral	-6	neutral	0,09	medium_impact	1,95	medium_impact	0,29	medium_impact	-0,8	0,5	0,8	33,67	21,31	N	0,37	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10612	10612	C	G	MI.15989	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	143	48	T	S	aCc/aGc	-1,09	0	0	benign	0	neutral	0,7	neutral	2,14	neutral	1,54	neutral	-0,08	neutral_impact	-0,51	neutral	0,83	neutral	1	neutral	-1	0,02	0,72	0,75	neutral	0,15	neutral	0,18	neutral	0,34	neutral	0,32	4	neutral	0,29	deleterious	0,85	neutral	-6	neutral	0,11	medium_impact	1,95	medium_impact	0,41	low_impact	-1,57	0,78	0,85	33,67	21,31	N	0,36	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8439	8439	A	T	MI.1599	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	74	25	Q	L	cAa/cTa	3,37	0,56	0	probably_damaging	0,94	neutral	0,65	neutral	1,64	deleterious	-5,42	deleterious	-6,99	medium_impact	2,54	neutral	0,99	neutral	0,35	deleterious	3,69	23,3	0,22571878	0,85	disease	0,76	disease	0,63	disease	0,7	disease	0,65	3	neutral	0,93	neutral	0,36	deleterious	1	deleterious	0,8	low_impact	-1,89	medium_impact	0,44	medium_impact	1,08	0,31	0,85	5,88	7,45	N	0,41	N	0,94	disease_causing	0,52	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10612	10612	C	T	MI.15990	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	143	48	T	I	aCc/aTc	-1,09	0	0	benign	0,01	neutral	0,56	neutral	1,99	neutral	-0,2	neutral	-0,21	neutral_impact	-0,52	neutral	0,81	neutral	0,97	deleterious	0,24	5,15	0,49	0,55	neutral	0,17	neutral	0,48	neutral	0,39	neutral	0,45	1	neutral	0,43	deleterious	0,78	neutral	-6	neutral	0,25	medium_impact	1,03	medium_impact	0,27	low_impact	-1,57	0,72	0,85	33,67	21,31	N	0,28	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10612	10612	C	A	MI.15991	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	143	48	T	N	aCc/aAc	-1,09	0	0	benign	0,11	neutral	0,41	neutral	1,96	neutral	-0,99	neutral	-1,92	low_impact	1,5	neutral	0,85	neutral	0,63	deleterious	0,79	9,43	0,49	0,55	neutral	0,35	disease	0,58	neutral	0,5	disease	0,5	0	neutral	0,53	deleterious	0,65	neutral	-6	neutral	0,25	medium_impact	0,03	medium_impact	0,12	medium_impact	0,12	0,82	0,85	33,67	21,31	N	0,32	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10614	10614	C	A	MI.15992	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	145	49	L	I	Ctc/Atc	-5,01	0	0	possibly_damaging	0,75	neutral	0,43	neutral	1,87	neutral	-1,2	neutral	-1,67	low_impact	1,29	neutral	0,76	neutral	0,74	neutral	1,14	11,44	0,71	0,75	neutral	0,41	neutral	0,42	neutral	0,37	neutral	0,46	1	neutral	0,75	neutral	0,34	neutral	-3	deleterious	0,45	low_impact	-1,24	medium_impact	0,14	medium_impact	-0,06	0,59	0,8	26,53	11,6	N	0,34	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10614	10614	C	T	MI.15993	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	145	49	L	F	Ctc/Ttc	-5,01	0	0	benign	0,17	neutral	0,69	neutral	1,83	neutral	-2,16	deleterious	-3,33	medium_impact	2,12	neutral	0,79	neutral	0,66	deleterious	1,98	16,11	0,54	0,6	neutral	0,33	disease	0,57	neutral	0,49	disease	0,51	0	neutral	0,19	deleterious	0,76	neutral	-3	neutral	0,19	medium_impact	-0,17	medium_impact	0,4	medium_impact	0,64	0,68	0,85	26,53	11,6	N	0,23	N	0,47	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10614	10614	C	G	MI.15994	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	145	49	L	V	Ctc/Gtc	-5,01	0	0	possibly_damaging	0,64	neutral	0,55	neutral	2,03	neutral	0,18	neutral	-2,5	low_impact	1,46	neutral	0,78	neutral	0,73	deleterious	0,71	8,91	0,56	0,6	neutral	0,36	neutral	0,41	neutral	0,49	neutral	0,46	1	neutral	0,6	neutral	0,46	neutral	-3	deleterious	0,44	low_impact	-1,03	medium_impact	0,26	medium_impact	0,09	0,72	0,85	26,53	11,6	N	0,26	N	0,3	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10615	10615	T	G	MI.15995	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	146	49	L	R	cTc/cGc	-0,4	0	0	probably_damaging	0,9	neutral	0,29	neutral	1,86	neutral	-1,46	deleterious	-5,11	medium_impact	3,16	neutral	0,71	damaging	0,25	deleterious	4,04	23,7	0,27	0,45	disease	0,86	disease	0,88	disease	0,59	disease	0,79	6	neutral	0,92	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-1,68	medium_impact	-0,01	medium_impact	1,51	0,65	0,8	26,53	11,6	N	0,34	N	0,73	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10615	10615	T	C	MI.15996	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	146	49	L	P	cTc/cCc	-0,4	0	0	probably_damaging	0,93	neutral	0,17	neutral	1,79	deleterious	-4,03	deleterious	-6	medium_impact	2,82	neutral	0,63	damaging	0,27	deleterious	3,8	23,4	0,33	0,5	disease	0,89	disease	0,87	disease	0,67	disease	0,79	6	neutral	0,96	neutral	0,12	deleterious	1	deleterious	0,81	low_impact	-1,83	medium_impact	-0,17	medium_impact	1,23	0,59	0,8	26,53	11,6	N	0,27	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10615	10615	T	A	MI.15997	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	146	49	L	H	cTc/cAc	-0,4	0	0	probably_damaging	0,96	neutral	0,43	neutral	1,79	deleterious	-3,5	deleterious	-5,94	medium_impact	1,99	neutral	0,81	neutral	0,36	deleterious	4,06	23,7	0,3	0,45	disease	0,9	disease	0,8	neutral	0,48	disease	0,75	5	neutral	0,96	neutral	0,24	deleterious	1	deleterious	0,81	low_impact	-2,07	medium_impact	0,14	medium_impact	0,53	0,49	0,8	26,53	11,6	N	0,24	N	0,84	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10617	10617	A	C	MI.15998	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	148	50	N	H	Aac/Cac	-6,16	0	0	probably_damaging	1	neutral	0,53	neutral	1,94	neutral	-1,49	deleterious	-3,93	neutral_impact	0,54	neutral	0,77	neutral	0,92	neutral	1,7	14,4	0,71	0,75	neutral	0,28	disease	0,73	neutral	0,35	disease	0,57	1	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,69	low_impact	-3,55	medium_impact	0,24	medium_impact	-0,69	0,52	0,8	23,47	11,07	N	0,25	N	0,58	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10617	10617	A	G	MI.15999	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	148	50	N	D	Aac/Gac	-6,16	0	0	probably_damaging	0,96	neutral	0,21	neutral	1,95	neutral	-0,92	deleterious	-3,81	medium_impact	2,8	neutral	0,81	neutral	0,6	neutral	0,9	10,06	0,8	0,85	neutral	0,29	disease	0,78	disease	0,52	disease	0,59	2	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,72	low_impact	-2,07	medium_impact	-0,11	medium_impact	1,21	0,48	0,8	23,47	11,07	N	0,36	N	0,87	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8533	8533	G	A	MI.16	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	7	3	E	K	Gaa/Aaa	-0,1	0,06	0	probably_damaging	0,95	neutral	0,35	neutral	4,69	neutral	-0,16	neutral	-1,47	low_impact	0,92	neutral	0,89	neutral	0,57	deleterious	2,08	16,72	0,65	0,7	neutral	0,39	neutral	0,26	neutral	0,25	neutral	0,46	1	neutral	0,96	neutral	0,2	neutral	-2	deleterious	0,64	low_impact	-1,97	medium_impact	0,14	medium_impact	-0,31	0,75	0,9	15,93	14,48	N	0,44	N	1	polymorphism	0,99	0,02	rs386829039	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8600	8600	T	A	MI.160	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	74	25	L	Q	cTa/cAa	-2,19	0	0	probably_damaging	1	deleterious	0,03	neutral	4,13	deleterious	-3,66	deleterious	-3,02	medium_impact	3	neutral	0,82	neutral	0,5	deleterious	3,81	23,4	0,21	0,65	disease	0,85	neutral	0,46	disease	0,57	disease	0,63	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,78	low_impact	-3,6	medium_impact	-0,56	medium_impact	1,47	0,59	0,9	10,18	13,06	N	0,37	N	0,71	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8439	8439	A	G	MI.1600	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	74	25	Q	R	cAa/cGa	3,37	0,56	0	probably_damaging	0,94	neutral	0,35	neutral	1,58	deleterious	-4,61	deleterious	-3,99	high_impact	3,86	neutral	0,98	neutral	0,34	deleterious	3,33	22,9	0,41328743	0,85	disease	0,64	disease	0,54	disease	0,79	disease	0,69	4	neutral	0,94	neutral	0,21	deleterious	2	deleterious	0,79	low_impact	-1,89	medium_impact	0,14	high_impact	2,21	0,54	0,85	5,88	7,45	P	0,58	P	0,77	polymorphism	0,93	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10617	10617	A	T	MI.16000	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	148	50	N	Y	Aac/Tac	-6,16	0	0	probably_damaging	1	neutral	1	neutral	1,97	neutral	-1,55	deleterious	-6,56	low_impact	1,52	neutral	0,81	damaging	0,2	deleterious	3,71	23,3	0,58	0,65	disease	0,6	disease	0,85	neutral	0,45	disease	0,76	5	deleterious	0,99	deleterious	0,5	neutral	-2	deleterious	0,78	low_impact	-3,55	high_impact	1,88	medium_impact	0,14	0,37	0,8	23,47	11,07	N	0,18	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10618	10618	A	C	MI.16001	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	149	50	N	T	aAc/aCc	0,75	0	0	probably_damaging	0,94	neutral	0,39	neutral	1,97	neutral	-0,91	deleterious	-4,56	low_impact	1,52	neutral	0,78	neutral	0,95	deleterious	2,06	16,63	0,67	0,7	neutral	0,32	disease	0,64	neutral	0,3	neutral	0,47	1	neutral	0,94	neutral	0,23	neutral	-2	deleterious	0,69	low_impact	-1,9	medium_impact	0,1	medium_impact	0,14	0,43	0,8	23,47	11,07	N	0,32	N	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10618	10618	A	T	MI.16002	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	149	50	N	I	aAc/aTc	0,75	0	0	probably_damaging	0,99	neutral	0,43	neutral	1,96	neutral	-2,34	deleterious	-7,47	medium_impact	2,02	neutral	0,78	neutral	0,43	deleterious	3,93	23,5	0,57	0,65	disease	0,55	disease	0,88	neutral	0,47	disease	0,73	5	deleterious	0,99	neutral	0,22	deleterious	1	deleterious	0,79	low_impact	-2,63	medium_impact	0,14	medium_impact	0,56	0,3	0,8	23,47	11,07	N	0,26	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10618	10618	A	G	MI.16003	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	149	50	N	S	aAc/aGc	0,75	0	0	possibly_damaging	0,52	neutral	0,44	neutral	2,01	neutral	-0,54	deleterious	-3,71	low_impact	0,88	neutral	0,75	neutral	0,95	deleterious	0,14	4,03	0,84	0,85	neutral	0,18	disease	0,63	neutral	0,34	neutral	0,44	1	neutral	0,56	neutral	0,46	neutral	-3	deleterious	0,67	medium_impact	-0,84	medium_impact	0,15	medium_impact	-0,4	0,2	0,8	23,47	11,07	N	0,35	N	0,8	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10619	10619	C	A	MI.16004	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	150	50	N	K	aaC/aaA	-0,4	0	0	probably_damaging	0,94	neutral	0,29	neutral	2	neutral	-0,28	deleterious	-4,87	medium_impact	2,25	neutral	0,79	neutral	0,28	deleterious	3,1	22,5	0,85	0,85	neutral	0,19	disease	0,85	neutral	0,49	disease	0,6	2	neutral	0,95	neutral	0,18	deleterious	1	deleterious	0,74	low_impact	-1,9	medium_impact	-0,01	medium_impact	0,75	0,55	0,8	23,47	11,07	N	0,29	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10619	10619	C	G	MI.16005	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	150	50	N	K	aaC/aaG	-0,4	0	0	probably_damaging	0,94	neutral	0,29	neutral	2	neutral	-0,28	deleterious	-4,87	medium_impact	2,25	neutral	0,79	neutral	0,28	deleterious	2,66	20,6	0,85	0,85	neutral	0,19	disease	0,85	neutral	0,49	disease	0,6	2	neutral	0,95	neutral	0,18	deleterious	1	deleterious	0,74	low_impact	-1,9	medium_impact	-0,01	medium_impact	0,75	0,55	0,8	23,47	11,07	N	0,29	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10620	10620	A	T	MI.16006	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	151	51	T	S	Acc/Tcc	-5,01	0	0	benign	0,18	neutral	0,51	neutral	1,84	neutral	-1,41	neutral	0,24	neutral_impact	-0,35	neutral	0,82	neutral	1	neutral	-0,52	0,2	0,65	0,7	neutral	0,11	neutral	0,21	neutral	0,31	neutral	0,35	3	neutral	0,39	deleterious	0,67	neutral	-6	neutral	0,14	medium_impact	-0,2	medium_impact	0,22	low_impact	-1,43	0,58	0,8	28,57	17,13	N	0,31	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10620	10620	A	C	MI.16007	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	151	51	T	P	Acc/Ccc	-5,01	0	0	possibly_damaging	0,55	neutral	0,22	neutral	1,77	deleterious	-3,21	neutral	-2,03	medium_impact	2,02	neutral	0,79	neutral	0,67	deleterious	1,81	15,05	0,3	0,45	neutral	0,37	disease	0,77	disease	0,63	disease	0,77	5	neutral	0,77	neutral	0,34	NA	0	deleterious	0,44	medium_impact	-0,88	medium_impact	-0,1	medium_impact	0,56	0,57	0,8	28,57	17,13	N	0,3	N	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10620	10620	A	G	MI.16008	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	151	51	T	A	Acc/Gcc	-5,01	0	0	benign	0,01	neutral	0,53	neutral	1,83	neutral	-1,54	neutral	-0,6	low_impact	1,26	neutral	0,83	neutral	0,93	neutral	-0,44	0,32	0,77	0,8	neutral	0,15	neutral	0,27	neutral	0,46	neutral	0,43	1	neutral	0,45	deleterious	0,76	neutral	-6	neutral	0,09	medium_impact	1,03	medium_impact	0,24	medium_impact	-0,08	0,38	0,8	28,57	17,13	N	0,29	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10621	10621	C	T	MI.16009	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	152	51	T	I	aCc/aTc	-1,78	0	0	benign	0,01	neutral	0,41	neutral	1,8	neutral	-2,26	neutral	-0,23	low_impact	1,32	neutral	0,81	neutral	0,92	deleterious	0,31	5,74	0,62	0,65	neutral	0,21	disease	0,51	neutral	0,38	neutral	0,45	1	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,12	medium_impact	-0,03	0,6	0,8	28,57	17,13	N	0,37	N	0,85	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8439	8439	A	C	MI.1601	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	74	25	Q	P	cAa/cCa	3,37	0,56	0	probably_damaging	0,96	neutral	0,21	neutral	1,58	deleterious	-6,33	deleterious	-5,99	medium_impact	2,44	neutral	0,97	damaging	0,24	deleterious	3,13	22,6	0,22453471	0,85	disease	0,83	disease	0,65	disease	0,78	disease	0,66	3	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,85	low_impact	-2,07	medium_impact	-0,03	medium_impact	0,99	0,49	0,85	5,88	7,45	N	0,51	P	0,9	disease_causing	0,58	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10621	10621	C	A	MI.16010	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	152	51	T	N	aCc/aAc	-1,78	0	0	possibly_damaging	0,62	neutral	0,38	neutral	1,8	neutral	-2,17	neutral	-0,89	low_impact	0,89	neutral	0,81	neutral	0,98	neutral	1,71	14,44	0,68	0,7	neutral	0,13	neutral	0,34	neutral	0,35	neutral	0,43	1	neutral	0,67	neutral	0,38	neutral	-3	neutral	0,36	medium_impact	-1	medium_impact	0,09	medium_impact	-0,39	0,75	0,85	28,57	17,13	N	0,37	N	0,07	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10621	10621	C	G	MI.16011	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	152	51	T	S	aCc/aGc	-1,78	0	0	benign	0,18	neutral	0,51	neutral	1,84	neutral	-1,41	neutral	0,24	neutral_impact	-0,35	neutral	0,82	neutral	1	neutral	-0,12	1,55	0,65	0,7	neutral	0,11	neutral	0,21	neutral	0,31	neutral	0,35	3	neutral	0,39	deleterious	0,67	neutral	-6	neutral	0,14	medium_impact	-0,2	medium_impact	0,22	low_impact	-1,43	0,58	0,8	28,57	17,13	N	0,32	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10623	10623	C	G	MI.16012	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	154	52	H	D	Cac/Gac	-6,16	0	0	possibly_damaging	0,83	neutral	0,23	neutral	2,06	neutral	-0,36	deleterious	-5,56	low_impact	1,13	neutral	0,82	neutral	0,62	deleterious	2,47	19,3	0,5	0,6	neutral	0,18	disease	0,55	disease	0,55	neutral	0,44	1	neutral	0,89	neutral	0,2	neutral	-3	deleterious	0,66	low_impact	-1,43	medium_impact	-0,08	medium_impact	-0,19	0,56	0,8	36,73	8,63	N	0,32	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10623	10623	C	A	MI.16013	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	154	52	H	N	Cac/Aac	-6,16	0	0	benign	0,12	neutral	0,34	neutral	2,03	neutral	-0,23	deleterious	-3,48	neutral_impact	-0,23	neutral	0,79	neutral	0,94	deleterious	2,42	18,95	0,79	0,8	neutral	0,12	neutral	0,35	neutral	0,37	neutral	0,44	1	neutral	0,61	deleterious	0,61	neutral	-6	deleterious	0,57	medium_impact	-0,01	medium_impact	0,05	low_impact	-1,33	0,63	0,8	36,73	8,63	N	0,31	N	0,29	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10623	10623	C	T	MI.16014	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	154	52	H	Y	Cac/Tac	-6,16	0	0	probably_damaging	0,95	neutral	1	neutral	1,95	neutral	-2,56	deleterious	-4,06	low_impact	1,62	neutral	0,83	neutral	0,46	deleterious	1,85	15,28	0,75	0,8	neutral	0,38	disease	0,58	neutral	0,49	disease	0,54	1	neutral	0,95	deleterious	0,53	neutral	-2	deleterious	0,7	low_impact	-1,97	high_impact	1,88	medium_impact	0,22	0,42	0,8	36,73	8,63	N	0,19	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10624	10624	A	C	MI.16015	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	155	52	H	P	cAc/cCc	1,21	0,21	0	probably_damaging	0,98	neutral	0,22	neutral	1,96	neutral	-2,1	deleterious	-6,78	low_impact	1,32	neutral	0,74	neutral	0,64	deleterious	3,19	22,7	0,4	0,5	neutral	0,33	disease	0,85	disease	0,65	disease	0,63	3	deleterious	0,98	neutral	0,12	neutral	-2	deleterious	0,77	low_impact	-2,35	medium_impact	-0,1	medium_impact	-0,03	0,43	0,8	36,73	8,63	N	0,32	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10624	10624	A	G	MI.16016	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	155	52	H	R	cAc/cGc	1,21	0,21	0	benign	0,17	neutral	0,36	neutral	1,99	neutral	-0,41	deleterious	-5,02	medium_impact	2,12	neutral	0,84	neutral	0,38	neutral	1,1	11,21	0,79	0,8	neutral	0,17	disease	0,66	neutral	0,47	disease	0,55	1	neutral	0,57	deleterious	0,6	neutral	-3	neutral	0,21	medium_impact	-0,17	medium_impact	0,07	medium_impact	0,64	0,46	0,8	36,73	8,63	N	0,32	N	0,86	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10624	10624	A	T	MI.16017	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	155	52	H	L	cAc/cTc	1,21	0,21	0	possibly_damaging	0,83	neutral	0,67	neutral	2	neutral	-1,13	deleterious	-7,26	low_impact	1,46	neutral	0,73	neutral	0,72	deleterious	3,61	23,2	0,53	0,6	neutral	0,23	disease	0,67	neutral	0,46	neutral	0,48	0	neutral	0,8	neutral	0,42	neutral	-3	deleterious	0,65	low_impact	-1,43	medium_impact	0,38	medium_impact	0,09	0,35	0,8	36,73	8,63	N	0,33	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10625	10625	C	G	MI.16018	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	156	52	H	Q	caC/caG	3,52	0,26	0	possibly_damaging	0,89	neutral	0,32	neutral	2,02	neutral	-0,06	deleterious	-4,66	neutral_impact	0,69	neutral	0,79	neutral	0,78	neutral	-0,1	1,73	0,92	0,95	neutral	0,12	neutral	0,33	neutral	0,35	neutral	0,44	1	neutral	0,9	neutral	0,22	neutral	-3	deleterious	0,6	low_impact	-1,64	medium_impact	0,03	medium_impact	-0,56	0,64	0,8	36,73	8,63	N	0,35	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10625	10625	C	A	MI.16019	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	156	52	H	Q	caC/caA	3,52	0,26	0	possibly_damaging	0,89	neutral	0,32	neutral	2,02	neutral	-0,06	deleterious	-4,66	neutral_impact	0,69	neutral	0,79	neutral	0,78	deleterious	0,12	3,84	0,92	0,95	neutral	0,12	neutral	0,33	neutral	0,35	neutral	0,44	1	neutral	0,9	neutral	0,22	neutral	-3	deleterious	0,6	low_impact	-1,64	medium_impact	0,03	medium_impact	-0,56	0,64	0,8	36,73	8,63	N	0,35	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8440	8440	A	T	MI.1602	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	75	25	Q	H	caA/caT	2,21	0,54	0,01	probably_damaging	0,99	neutral	0,54	neutral	1,57	deleterious	-6,23	deleterious	-4,99	high_impact	3,86	neutral	0,98	neutral	0,32	deleterious	3,45	23	0,41328743	0,85	disease	0,83	neutral	0,5	disease	0,76	disease	0,67	3	deleterious	0,99	neutral	0,28	deleterious	2	deleterious	0,85	low_impact	-2,65	medium_impact	0,33	high_impact	2,21	0,63	0,85	5,88	7,45	N	0,48	N	0,82	polymorphism	0,89	0,35	rs386829036	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10626	10626	T	A	MI.16020	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	157	53	S	T	Tcc/Acc	-2,01	0	0	benign	0,02	neutral	0,41	neutral	1,93	neutral	-0,91	neutral	-0,57	low_impact	1,55	neutral	0,82	neutral	0,86	deleterious	0,36	6,29	0,51	0,6	neutral	0,19	neutral	0,23	neutral	0,26	neutral	0,44	1	neutral	0,57	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	0,75	medium_impact	0,12	medium_impact	0,16	0,56	0,8	33,67	16,38	N	0,42	N	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10626	10626	T	G	MI.16021	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	157	53	S	A	Tcc/Gcc	-2,01	0	0	benign	0,18	neutral	0,54	neutral	1,93	neutral	-0,97	neutral	-0,62	low_impact	1,82	neutral	0,75	neutral	0,85	neutral	-0,21	1,03	0,67	0,7	neutral	0,22	neutral	0,28	neutral	0,43	neutral	0,44	1	neutral	0,35	deleterious	0,68	neutral	-6	neutral	0,16	medium_impact	-0,2	medium_impact	0,25	medium_impact	0,39	0,55	0,8	33,67	16,38	N	0,35	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10626	10626	T	C	MI.16022	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	157	53	S	P	Tcc/Ccc	-2,01	0	0	possibly_damaging	0,62	neutral	0,21	neutral	1,88	neutral	-2,49	neutral	-2,31	medium_impact	2,35	neutral	0,74	neutral	0,55	deleterious	2,45	19,15	0,47	0,55	neutral	0,49	disease	0,87	disease	0,62	disease	0,76	5	neutral	0,8	neutral	0,3	NA	0	deleterious	0,64	medium_impact	-1	medium_impact	-0,11	medium_impact	0,83	0,53	0,8	33,67	16,38	N	0,31	N	0,64	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10627	10627	C	T	MI.16023	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	158	53	S	F	tCc/tTc	-0,63	0	0	benign	0,01	neutral	0,71	neutral	1,9	neutral	-1,72	neutral	3,19	neutral_impact	0,66	neutral	0,9	neutral	0,98	neutral	-0,21	1,05	0,42	0,55	neutral	0,2	disease	0,6	neutral	0,35	neutral	0,45	1	neutral	0,28	deleterious	0,85	neutral	-6	neutral	0,14	medium_impact	1,03	medium_impact	0,43	medium_impact	-0,59	0,31	0,8	33,67	16,38	N	0,25	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10627	10627	C	A	MI.16024	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	158	53	S	Y	tCc/tAc	-0,63	0	0	benign	0,26	neutral	1	neutral	1,91	neutral	-1,44	neutral	2,27	low_impact	1,38	neutral	0,84	neutral	0,9	neutral	-0,34	0,54	0,39	0,5	neutral	0,4	disease	0,73	neutral	0,31	disease	0,56	1	neutral	0,26	deleterious	0,87	neutral	-6	neutral	0,29	medium_impact	-0,39	high_impact	1,88	medium_impact	0,02	0,62	0,8	33,67	16,38	N	0,2	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10627	10627	C	G	MI.16025	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	158	53	S	C	tCc/tGc	-0,63	0	0	possibly_damaging	0,89	neutral	0,18	neutral	1,87	deleterious	-3,13	neutral	-1,13	medium_impact	2,52	neutral	0,72	neutral	0,41	deleterious	0,42	6,79	0,47	0,55	disease	0,54	disease	0,68	neutral	0,36	disease	0,52	0	neutral	0,94	neutral	0,15	NA	0	deleterious	0,65	low_impact	-1,64	medium_impact	-0,16	medium_impact	0,97	0,54	0,8	33,67	16,38	N	0,42	N	0,43	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10629	10629	C	A	MI.16026	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	160	54	L	I	Ctc/Atc	-6,63	0	0	benign	0,07	neutral	0,4	neutral	1,96	neutral	-0,57	neutral	0,04	neutral_impact	0,31	neutral	0,82	neutral	0,97	neutral	1,17	11,59	0,64	0,7	neutral	0,19	neutral	0,3	neutral	0,2	neutral	0,44	1	neutral	0,55	deleterious	0,67	neutral	-6	neutral	0,16	medium_impact	0,23	medium_impact	0,11	medium_impact	-0,88	0,61	0,8	33,67	23,2	N	0,43	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10629	10629	C	G	MI.16027	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	160	54	L	V	Ctc/Gtc	-6,63	0	0	benign	0,01	neutral	0,51	neutral	1,96	neutral	-0,6	neutral	0,34	low_impact	1,34	neutral	0,82	neutral	0,9	deleterious	0,44	6,93	0,65	0,7	neutral	0,16	neutral	0,31	neutral	0,23	neutral	0,45	1	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	0,22	medium_impact	-0,02	0,46	0,8	33,67	23,2	N	0,35	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10629	10629	C	T	MI.16028	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	160	54	L	F	Ctc/Ttc	-6,63	0	0	benign	0,34	neutral	0,71	neutral	1,91	neutral	-1,51	neutral	-1,1	neutral_impact	0,22	neutral	0,8	neutral	0,97	deleterious	2,33	18,35	0,61	0,65	neutral	0,3	neutral	0,36	neutral	0,4	neutral	0,44	1	neutral	0,25	deleterious	0,69	neutral	-6	deleterious	0,43	medium_impact	-0,54	medium_impact	0,43	medium_impact	-0,95	0,48	0,8	33,67	23,2	N	0,28	N	0,27	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10630	10630	T	C	MI.16029	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	161	54	L	P	cTc/cCc	-2,24	0	0	benign	0	neutral	0,22	neutral	2,23	neutral	1,55	neutral	-0,86	neutral_impact	0,01	neutral	0,87	neutral	0,87	deleterious	0,31	5,79	0,37	0,5	neutral	0,23	disease	0,71	neutral	0,44	disease	0,56	1	neutral	0,78	deleterious	0,61	neutral	-6	neutral	0,19	medium_impact	1,95	medium_impact	-0,1	low_impact	-1,13	0,41	0,8	33,67	23,2	N	0,33	N	0,02	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8440	8440	A	C	MI.1603	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	75	25	Q	H	caA/caC	2,21	0,54	0,01	probably_damaging	0,99	neutral	0,54	neutral	1,57	deleterious	-6,23	deleterious	-4,99	high_impact	3,86	neutral	0,98	neutral	0,32	deleterious	3,32	22,9	0,41328743	0,85	disease	0,83	neutral	0,5	disease	0,76	disease	0,67	3	deleterious	0,99	neutral	0,28	deleterious	2	deleterious	0,85	low_impact	-2,65	medium_impact	0,33	high_impact	2,21	0,63	0,85	5,88	7,45	N	0,48	N	0,82	polymorphism	0,89	0,35	rs386829036	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10630	10630	T	A	MI.16030	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	161	54	L	H	cTc/cAc	-2,24	0	0	possibly_damaging	0,68	neutral	0,53	neutral	1,89	neutral	-2,42	neutral	-1,98	low_impact	1,8	neutral	0,83	neutral	0,6	deleterious	2,79	21,3	0,44	0,55	neutral	0,36	disease	0,6	neutral	0,45	disease	0,55	1	neutral	0,65	neutral	0,43	neutral	-3	deleterious	0,58	low_impact	-1,1	medium_impact	0,24	medium_impact	0,37	0,46	0,8	33,67	23,2	N	0,25	N	0,41	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10630	10630	T	G	MI.16031	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	161	54	L	R	cTc/cGc	-2,24	0	0	benign	0,23	neutral	0,34	neutral	1,91	neutral	-1,64	neutral	-1,41	medium_impact	2,15	neutral	0,79	neutral	0,51	neutral	1,47	13,14	0,41	0,5	neutral	0,24	disease	0,81	neutral	0,5	disease	0,76	5	neutral	0,59	deleterious	0,56	neutral	-3	neutral	0,38	medium_impact	-0,32	medium_impact	0,05	medium_impact	0,66	0,49	0,8	33,67	23,2	N	0,3	N	0,34	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10632	10632	T	A	MI.16032	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	163	55	L	M	Tta/Ata	-10,08	0	0	possibly_damaging	0,76	neutral	0,22	neutral	1,62	deleterious	-3,4	neutral	-1,05	low_impact	0,96	neutral	0,77	neutral	0,94	deleterious	2,19	17,47	0,44	0,55	neutral	0,45	neutral	0,22	neutral	0,23	neutral	0,41	2	neutral	0,85	neutral	0,23	neutral	-3	deleterious	0,66	low_impact	-1,26	medium_impact	-0,1	medium_impact	-0,33	0,63	0,8	31,63	14,43	N	0,46	N	0,5	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10632	10632	T	G	MI.16033	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	163	55	L	V	Tta/Gta	-10,08	0	0	possibly_damaging	0,9	neutral	0,5	neutral	1,72	neutral	-1,7	neutral	-1,6	low_impact	1,34	neutral	0,77	neutral	0,88	neutral	1,62	13,94	0,58	0,65	neutral	0,28	neutral	0,31	neutral	0,39	neutral	0,45	1	neutral	0,89	neutral	0,3	neutral	-3	deleterious	0,65	low_impact	-1,68	medium_impact	0,21	medium_impact	-0,02	0,3	0,8	31,63	14,43	N	0,34	N	0,27	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10633	10633	T	C	MI.16034	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	164	55	L	S	tTa/tCa	-2,71	0	0	probably_damaging	0,98	neutral	0,42	neutral	1,72	neutral	-1,71	deleterious	-3,86	neutral_impact	-0,05	neutral	0,76	neutral	0,97	neutral	1,49	13,27	0,38	0,5	neutral	0,19	neutral	0,14	neutral	0,3	neutral	0,28	4	deleterious	0,98	neutral	0,22	neutral	-2	deleterious	0,64	low_impact	-2,35	medium_impact	0,13	low_impact	-1,18	0,41	0,8	31,63	14,43	N	0,35	N	0,18	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10633	10633	T	G	MI.16035	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	164	55	L	W	tTa/tGa	-2,71	0	0	probably_damaging	1	neutral	0,18	neutral	1,58	deleterious	-6,1	deleterious	-4,78	medium_impact	2,34	neutral	0,79	damaging	0,08	deleterious	2,52	19,58	0,27	0,45	disease	0,75	disease	0,6	neutral	0,48	neutral	0,5	0	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	-0,16	medium_impact	0,82	0,49	0,8	31,63	14,43	N	0,25	N	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10634	10634	A	T	MI.16036	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	165	55	L	F	ttA/ttT	-0,17	0	0	probably_damaging	0,98	neutral	0,7	neutral	1,64	neutral	-2,96	deleterious	-2,95	low_impact	1,72	neutral	0,78	damaging	0,24	neutral	1,55	13,56	0,5	0,6	neutral	0,43	neutral	0,4	neutral	0,39	neutral	0,45	1	neutral	0,98	neutral	0,36	neutral	-2	deleterious	0,68	low_impact	-2,35	medium_impact	0,41	medium_impact	0,3	0,35	0,8	31,63	14,43	N	0,24	N	0,46	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10634	10634	A	C	MI.16037	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	165	55	L	F	ttA/ttC	-0,17	0	0	probably_damaging	0,98	neutral	0,7	neutral	1,64	neutral	-2,96	deleterious	-2,95	low_impact	1,72	neutral	0,78	damaging	0,24	neutral	1,44	13,01	0,5	0,6	neutral	0,43	neutral	0,4	neutral	0,39	neutral	0,45	1	neutral	0,98	neutral	0,36	neutral	-2	deleterious	0,68	low_impact	-2,35	medium_impact	0,41	medium_impact	0,3	0,35	0,8	31,63	14,43	N	0,21	N	0,46	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10635	10635	G	A	MI.16038	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	166	56	A	T	Gcc/Acc	-2,71	0	0	benign	0,01	neutral	0,38	neutral	1,98	neutral	-0,28	neutral	-0,21	neutral_impact	0,04	neutral	0,85	neutral	0,98	deleterious	0,67	8,61	0,63	0,7	neutral	0,25	neutral	0,29	neutral	0,18	neutral	0,44	1	neutral	0,61	deleterious	0,69	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,09	low_impact	-1,1	0,47	0,8	31,63	17,2	N	0,52	P	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10635	10635	G	T	MI.16039	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	166	56	A	S	Gcc/Tcc	-2,71	0	0	benign	0,01	neutral	0,49	neutral	1,99	neutral	-0,12	neutral	0,66	neutral_impact	-0,26	neutral	0,8	neutral	0,93	neutral	-0,25	0,84	0,65	0,7	neutral	0,13	neutral	0,22	neutral	0,18	neutral	0,39	2	neutral	0,5	deleterious	0,74	neutral	-6	neutral	0,23	medium_impact	1,03	medium_impact	0,2	low_impact	-1,36	0,77	0,85	31,63	17,2	N	0,41	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8441	8441	C	A	MI.1604	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	76	26	L	M	Cta/Ata	-0,8	0	0	probably_damaging	1	neutral	0,35	neutral	1,1	deleterious	-5,36	neutral	-1,99	medium_impact	2,64	neutral	0,99	neutral	0,5	deleterious	3,79	23,4	0,48904297	0,85	disease	0,63	neutral	0,35	disease	0,53	neutral	0,26	5	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,14	medium_impact	1,17	0,86	0,9	1,47	7,57	N	0,51	P	0,61	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10635	10635	G	C	MI.16040	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	166	56	A	P	Gcc/Ccc	-2,71	0	0	benign	0,42	neutral	0,19	neutral	2,15	neutral	1,42	neutral	-2,31	low_impact	1,79	neutral	0,76	neutral	0,65	deleterious	2,23	17,73	0,35	0,5	neutral	0,45	disease	0,76	disease	0,51	disease	0,59	2	neutral	0,78	neutral	0,39	neutral	-6	deleterious	0,62	medium_impact	-0,68	medium_impact	-0,14	medium_impact	0,36	0,79	0,85	31,63	17,2	N	0,35	N	0,75	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10636	10636	C	T	MI.16041	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	167	56	A	V	gCc/gTc	-0,63	0	0	benign	0,01	neutral	0,5	neutral	2,06	neutral	0,74	neutral	-1,46	low_impact	1,25	neutral	0,82	neutral	0,67	neutral	0,96	10,43	0,55	0,6	neutral	0,26	neutral	0,44	neutral	0,35	neutral	0,47	1	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	0,21	medium_impact	-0,09	0,57	0,8	31,63	17,2	N	0,33	N	0,06	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10636	10636	C	A	MI.16042	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	167	56	A	D	gCc/gAc	-0,63	0	0	benign	0,34	neutral	0,2	neutral	1,95	neutral	-1,11	neutral	-2,23	low_impact	1,28	neutral	0,8	neutral	0,36	deleterious	3,02	22,3	0,42	0,5	neutral	0,3	disease	0,74	neutral	0,44	disease	0,53	1	neutral	0,76	neutral	0,43	neutral	-6	deleterious	0,52	medium_impact	-0,54	medium_impact	-0,12	medium_impact	-0,07	0,63	0,8	31,63	17,2	N	0,29	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10636	10636	C	G	MI.16043	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	167	56	A	G	gCc/gGc	-0,63	0	0	benign	0,12	neutral	0,4	neutral	2,05	neutral	0,67	neutral	-2	low_impact	0,86	neutral	0,84	neutral	0,68	neutral	0,93	10,25	0,61	0,65	neutral	0,36	neutral	0,46	neutral	0,35	neutral	0,49	0	neutral	0,54	deleterious	0,64	neutral	-6	neutral	0,35	medium_impact	-0,01	medium_impact	0,11	medium_impact	-0,42	0,78	0,85	31,63	17,2	N	0,32	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10638	10638	A	C	MI.16044	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	169	57	N	H	Aat/Cat	-12,16	0	0	possibly_damaging	0,69	neutral	0,54	neutral	1,99	neutral	-0,23	neutral	0,35	medium_impact	2,16	neutral	0,85	neutral	0,64	neutral	1,8	14,97	0,75	0,8	neutral	0,36	disease	0,52	disease	0,6	disease	0,73	5	neutral	0,66	neutral	0,43	NA	0	deleterious	0,61	low_impact	-1,12	medium_impact	0,25	medium_impact	0,67	0,57	0,8	33,67	21,76	N	0,27	N	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10638	10638	A	G	MI.16045	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	169	57	N	D	Aat/Gat	-12,16	0	0	possibly_damaging	0,54	neutral	0,21	neutral	1,99	neutral	-0,24	neutral	-1,09	medium_impact	2,16	neutral	0,83	neutral	0,47	deleterious	2,69	20,8	0,75	0,8	neutral	0,24	disease	0,55	disease	0,59	disease	0,73	5	neutral	0,78	neutral	0,34	NA	0	deleterious	0,62	medium_impact	-0,87	medium_impact	-0,11	medium_impact	0,67	0,55	0,8	33,67	21,76	N	0,37	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10638	10638	A	T	MI.16046	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	169	57	N	Y	Aat/Tat	-12,16	0	0	benign	0,02	neutral	1	neutral	2,01	neutral	0,34	neutral	2,25	neutral_impact	-0,06	neutral	0,85	neutral	0,95	deleterious	0,25	5,25	0,58	0,65	neutral	0,41	disease	0,55	neutral	0,46	neutral	0,46	1	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,16	medium_impact	0,75	high_impact	1,88	low_impact	-1,19	0,42	0,8	33,67	21,76	N	0,2	N	0,58	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10639	10639	A	C	MI.16047	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	170	57	N	T	aAt/aCt	-0,63	0	0	benign	0,05	neutral	0,4	neutral	2,02	neutral	0,59	neutral	0,14	neutral_impact	0,55	neutral	0,86	neutral	0,98	neutral	1,7	14,39	0,7	0,75	neutral	0,11	neutral	0,23	neutral	0,45	neutral	0,42	2	neutral	0,57	deleterious	0,68	neutral	-6	deleterious	0,54	medium_impact	0,37	medium_impact	0,11	medium_impact	-0,68	0,58	0,8	33,67	21,76	N	0,34	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10639	10639	A	G	MI.16048	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	170	57	N	S	aAt/aGt	-0,63	0	0	benign	0,27	neutral	0,41	neutral	2,08	neutral	1,45	neutral	0,33	neutral_impact	-0,98	neutral	0,92	neutral	0,99	deleterious	0,41	6,74	0,74	0,8	neutral	0,16	neutral	0,11	neutral	0,48	neutral	0,32	4	neutral	0,5	deleterious	0,57	neutral	-6	deleterious	0,48	medium_impact	-0,41	medium_impact	0,12	low_impact	-1,96	0,34	0,8	33,67	21,76	N	0,38	N	0,02	polymorphism	1	0,01	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	10639	10639	A	T	MI.16049	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	170	57	N	I	aAt/aTt	-0,63	0	0	benign	0,37	neutral	0,4	neutral	2,01	neutral	0,17	neutral	0,02	neutral_impact	0,26	neutral	0,87	neutral	0,94	deleterious	2,79	21,3	0,58	0,65	neutral	0,29	disease	0,66	neutral	0,47	disease	0,54	1	neutral	0,53	deleterious	0,52	neutral	-6	deleterious	0,6	medium_impact	-0,59	medium_impact	0,11	medium_impact	-0,92	0,36	0,8	33,67	21,76	N	0,31	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8441	8441	C	G	MI.1605	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	76	26	L	V	Cta/Gta	-0,8	0	0	probably_damaging	0,97	neutral	0,47	neutral	1,25	deleterious	-4,54	deleterious	-3	medium_impact	3,34	neutral	0,99	damaging	0,14	deleterious	3,25	22,8	0,57564883	0,85	disease	0,55	neutral	0,27	disease	0,65	neutral	0,17	7	neutral	0,97	neutral	0,25	deleterious	1	deleterious	0,77	low_impact	-2,19	medium_impact	0,26	medium_impact	1,77	0,7	0,85	1,47	7,57	N	0,45	N	0,46	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10640	10640	T	G	MI.16050	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	171	57	N	K	aaT/aaG	-0,63	0	0	possibly_damaging	0,46	neutral	0,3	neutral	2,02	neutral	0,63	neutral	-0,87	low_impact	1,81	neutral	0,83	neutral	0,48	deleterious	2,84	21,6	0,75	0,8	neutral	0,16	disease	0,63	disease	0,6	disease	0,75	5	neutral	0,66	neutral	0,42	neutral	-3	deleterious	0,6	medium_impact	-0,74	medium_impact	0,01	medium_impact	0,38	0,61	0,8	33,67	21,76	N	0,31	N	0,63	polymorphism	1	0,01	rs386419955	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10640	10640	T	A	MI.16051	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	171	57	N	K	aaT/aaA	-0,63	0	0	possibly_damaging	0,46	neutral	0,3	neutral	2,02	neutral	0,63	neutral	-0,87	low_impact	1,81	neutral	0,83	neutral	0,48	deleterious	3,16	22,6	0,75	0,8	neutral	0,16	disease	0,63	disease	0,6	disease	0,75	5	neutral	0,66	neutral	0,42	neutral	-3	deleterious	0,6	medium_impact	-0,74	medium_impact	0,01	medium_impact	0,38	0,61	0,8	33,67	21,76	N	0,31	N	0,63	polymorphism	1	0,01	rs386419955	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10641	10641	A	T	MI.16052	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	172	58	I	F	Att/Ttt	-7,55	0	0	possibly_damaging	0,69	neutral	0,81	neutral	1,91	neutral	-1,39	neutral	-1,74	low_impact	0,82	neutral	0,81	neutral	0,54	deleterious	2,16	17,22	0,56	0,6	neutral	0,25	disease	0,55	neutral	0,5	disease	0,53	1	neutral	0,63	deleterious	0,56	neutral	-3	deleterious	0,6	low_impact	-1,12	medium_impact	0,56	medium_impact	-0,45	0,71	0,85	31,63	19,86	N	0,23	N	0,43	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10641	10641	A	G	MI.16053	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	172	58	I	V	Att/Gtt	-7,55	0	0	possibly_damaging	0,44	neutral	0,58	neutral	2,03	neutral	0,27	neutral	-0,02	low_impact	1,32	neutral	0,85	neutral	0,94	neutral	-0,92	0,02	0,71	0,75	neutral	0,13	neutral	0,2	neutral	0,39	neutral	0,36	3	neutral	0,4	deleterious	0,57	neutral	-3	neutral	0,28	medium_impact	-0,71	medium_impact	0,29	medium_impact	-0,03	0,71	0,85	31,63	19,86	N	0,3	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10641	10641	A	C	MI.16054	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	172	58	I	L	Att/Ctt	-7,55	0	0	benign	0,14	neutral	0,86	neutral	2,04	neutral	0,4	neutral	-0,12	low_impact	0,94	neutral	0,75	neutral	0,8	neutral	-0,93	0,02	0,34	0,5	neutral	0,11	neutral	0,25	neutral	0,31	neutral	0,41	2	neutral	0,06	deleterious	0,86	neutral	-6	neutral	0,17	medium_impact	-0,08	medium_impact	0,65	medium_impact	-0,35	0,68	0,85	31,63	19,86	N	0,31	N	0,3	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10642	10642	T	G	MI.16055	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	173	58	I	S	aTt/aGt	-0,63	0	0	possibly_damaging	0,56	neutral	0,49	neutral	1,93	neutral	-1,03	neutral	-1,66	neutral_impact	0,08	neutral	0,81	neutral	0,9	neutral	1,63	14	0,45	0,55	neutral	0,23	neutral	0,43	neutral	0,42	neutral	0,44	1	neutral	0,55	neutral	0,47	neutral	-3	deleterious	0,61	medium_impact	-0,9	medium_impact	0,2	low_impact	-1,07	0,64	0,8	31,63	19,86	N	0,31	N	0,39	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10642	10642	T	A	MI.16056	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	173	58	I	N	aTt/aAt	-0,63	0	0	possibly_damaging	0,83	neutral	0,3	neutral	1,88	neutral	-2,57	deleterious	-2,8	medium_impact	1,98	neutral	0,86	neutral	0,56	deleterious	3,11	22,5	0,44	0,55	neutral	0,37	disease	0,61	disease	0,55	disease	0,72	4	neutral	0,86	neutral	0,24	NA	0	deleterious	0,68	low_impact	-1,43	medium_impact	0,01	medium_impact	0,52	0,66	0,8	31,63	19,86	N	0,32	N	0,52	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10642	10642	T	C	MI.16057	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	173	58	I	T	aTt/aCt	-0,63	0	0	benign	0,06	neutral	0,37	neutral	1,95	neutral	-0,6	neutral	-0,97	neutral_impact	0,64	neutral	0,85	neutral	0,98	deleterious	0,46	7,15	0,53	0,6	neutral	0,14	neutral	0,24	neutral	0,43	neutral	0,41	2	neutral	0,59	deleterious	0,66	neutral	-6	deleterious	0,52	medium_impact	0,29	medium_impact	0,08	medium_impact	-0,6	0,63	0,8	31,63	19,86	N	0,41	N	0,15	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10643	10643	T	A	MI.16058	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	174	58	I	M	atT/atA	0,52	0	0	benign	0,11	neutral	0,38	neutral	1,95	neutral	-0,66	neutral	1,04	neutral_impact	-0,67	neutral	0,86	neutral	0,98	neutral	-0,79	0,04	0,65	0,7	neutral	0,11	neutral	0,12	neutral	0,35	neutral	0,33	3	neutral	0,56	deleterious	0,64	neutral	-6	neutral	0,15	medium_impact	0,03	medium_impact	0,09	low_impact	-1,7	0,79	0,85	31,63	19,86	N	0,39	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10643	10643	T	G	MI.16059	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	174	58	I	M	atT/atG	0,52	0	0	benign	0,11	neutral	0,38	neutral	1,95	neutral	-0,66	neutral	1,04	neutral_impact	-0,67	neutral	0,86	neutral	0,98	neutral	-1,14	0,01	0,65	0,7	neutral	0,11	neutral	0,12	neutral	0,35	neutral	0,33	3	neutral	0,56	deleterious	0,64	neutral	-6	neutral	0,15	medium_impact	0,03	medium_impact	0,09	low_impact	-1,7	0,79	0,85	31,63	19,86	N	0,39	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8442	8442	T	C	MI.1606	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	77	26	L	P	cTa/cCa	-1,03	0	0	probably_damaging	1	neutral	0,4	neutral	1,04	deleterious	-7,72	deleterious	-6,99	low_impact	1,54	neutral	0,97	damaging	0,08	deleterious	3,85	23,4	0,17170724	0,85	disease	0,89	disease	0,7	disease	0,65	disease	0,74	5	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,88	low_impact	-3,6	medium_impact	0,19	medium_impact	0,22	0,57	0,85	1,47	7,57	N	0,36	N	0,97	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10644	10644	G	A	MI.16060	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	175	59	V	M	Gtg/Atg	-5,24	0	0	benign	0,03	neutral	0,52	neutral	1,95	neutral	-0,59	neutral	0,21	neutral_impact	-1,77	neutral	0,87	neutral	0,94	neutral	-0,14	1,47	0,58	0,65	neutral	0,13	neutral	0,16	neutral	0,23	neutral	0,26	5	neutral	0,45	deleterious	0,75	neutral	-6	neutral	0,08	medium_impact	0,58	medium_impact	0,23	low_impact	-2,62	0,92	0,95	28,57	15,27	N	0,3	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10644	10644	G	T	MI.16061	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	175	59	V	L	Gtg/Ttg	-5,24	0	0	benign	0,01	neutral	1	neutral	2,3	neutral	1,78	neutral	0,02	neutral_impact	-1,74	neutral	0,8	neutral	0,95	neutral	-0,76	0,05	0,49	0,55	neutral	0,17	neutral	0,27	neutral	0,22	neutral	0,42	2	neutral	0,01	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,03	high_impact	1,88	low_impact	-2,6	0,71	0,85	28,57	15,27	N	0,3	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10644	10644	G	C	MI.16062	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	175	59	V	L	Gtg/Ctg	-5,24	0	0	benign	0,01	neutral	1	neutral	2,3	neutral	1,78	neutral	0,02	neutral_impact	-1,74	neutral	0,8	neutral	0,95	neutral	-0,91	0,03	0,49	0,55	neutral	0,17	neutral	0,27	neutral	0,22	neutral	0,42	2	neutral	0,01	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,03	high_impact	1,88	low_impact	-2,6	0,71	0,85	28,57	15,27	N	0,3	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10645	10645	T	A	MI.16063	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	176	59	V	E	gTg/gAg	-0,63	0	0	possibly_damaging	0,45	neutral	0,3	neutral	1,87	deleterious	-3,17	deleterious	-3,97	low_impact	1,32	neutral	0,82	neutral	0,44	deleterious	2,7	20,8	0,25	0,45	neutral	0,49	disease	0,74	disease	0,58	disease	0,75	5	neutral	0,66	neutral	0,43	neutral	-3	deleterious	0,5	medium_impact	-0,72	medium_impact	0,01	medium_impact	-0,03	0,61	0,8	28,57	15,27	N	0,29	N	0,43	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10645	10645	T	G	MI.16064	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	176	59	V	G	gTg/gGg	-0,63	0	0	benign	0,36	neutral	0,48	neutral	1,89	neutral	-1,91	deleterious	-4,8	neutral_impact	0,77	neutral	0,81	neutral	0,72	deleterious	0,49	7,37	0,32	0,5	neutral	0,48	disease	0,58	neutral	0,46	disease	0,51	0	neutral	0,44	deleterious	0,56	neutral	-6	neutral	0,32	medium_impact	-0,57	medium_impact	0,19	medium_impact	-0,49	0,59	0,8	28,57	15,27	N	0,26	N	0,37	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10645	10645	T	C	MI.16065	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	176	59	V	A	gTg/gCg	-0,63	0	0	benign	0,02	neutral	0,63	neutral	1,95	neutral	-0,61	neutral	-2,25	neutral_impact	-1,25	neutral	0,77	neutral	1	neutral	-0,83	0,04	0,54	0,6	neutral	0,12	neutral	0,13	neutral	0,28	neutral	0,26	5	neutral	0,34	deleterious	0,81	neutral	-6	neutral	0,13	medium_impact	0,75	medium_impact	0,34	low_impact	-2,19	0,72	0,85	28,57	15,27	N	0,34	N	0,21	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10647	10647	C	T	MI.16066	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	178	60	P	S	Cct/Tct	-11,93	0	0	possibly_damaging	0,54	neutral	0,41	neutral	1,93	neutral	-0,79	deleterious	-7,8	low_impact	1,48	neutral	0,79	neutral	0,44	deleterious	2,14	17,1	0,3	0,45	neutral	0,16	disease	0,95	disease	0,69	disease	0,8	6	neutral	0,59	neutral	0,44	neutral	-3	neutral	0,37	medium_impact	-0,87	medium_impact	0,12	medium_impact	0,1	0,44	0,8	52,04	12,37	N	0,27	N	0,99	polymorphism	0,58	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10647	10647	C	G	MI.16067	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	178	60	P	A	Cct/Gct	-11,93	0	0	possibly_damaging	0,78	neutral	0,51	neutral	2,01	neutral	0,07	deleterious	-7,8	medium_impact	2,52	neutral	0,69	neutral	0,42	deleterious	2,8	21,4	0,46	0,55	neutral	0,33	disease	0,88	disease	0,75	disease	0,78	6	neutral	0,75	neutral	0,37	NA	0	deleterious	0,63	low_impact	-1,31	medium_impact	0,22	medium_impact	0,97	0,77	0,85	52,04	12,37	N	0,35	N	0,98	polymorphism	0,69	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10647	10647	C	A	MI.16068	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	178	60	P	T	Cct/Act	-11,93	0	0	benign	0,29	neutral	0,4	neutral	1,91	neutral	-1,34	deleterious	-7,8	medium_impact	2,77	neutral	0,71	neutral	0,33	deleterious	1,88	15,49	0,44	0,55	neutral	0,42	disease	0,94	disease	0,75	disease	0,82	6	neutral	0,52	deleterious	0,56	neutral	-3	neutral	0,35	medium_impact	-0,45	medium_impact	0,11	medium_impact	1,18	0,8	0,85	52,04	12,37	N	0,39	N	0,98	polymorphism	0,59	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10648	10648	C	T	MI.16069	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	179	60	P	L	cCt/cTt	4,44	0,99	0	probably_damaging	0,94	neutral	0,67	neutral	1,94	neutral	-0,65	deleterious	-9,74	medium_impact	2,09	neutral	0,65	neutral	0,35	deleterious	4,28	24	0,23	0,45	neutral	0,27	disease	0,97	disease	0,7	disease	0,83	7	neutral	0,93	neutral	0,37	deleterious	1	deleterious	0,77	low_impact	-1,9	medium_impact	0,38	medium_impact	0,61	0,73	0,85	52,04	12,37	N	0,42	N	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8442	8442	T	G	MI.1607	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	77	26	L	R	cTa/cGa	-1,03	0	0	probably_damaging	1	neutral	0,29	neutral	1,04	deleterious	-7	deleterious	-5,99	high_impact	3,68	neutral	0,97	damaging	0,05	deleterious	4,07	23,7	0,16813254	0,85	disease	0,86	disease	0,74	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,07	high_impact	2,06	0,42	0,85	1,47	7,57	N	0,42	N	0,96	polymorphism	0,93	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10648	10648	C	G	MI.16070	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	179	60	P	R	cCt/cGt	4,44	0,99	0	probably_damaging	0,97	neutral	0,35	neutral	1,86	neutral	-2,93	deleterious	-8,79	high_impact	4,16	neutral	0,62	damaging	0,27	deleterious	3,55	23,1	0,13	0,4	disease	0,53	disease	0,97	disease	0,85	disease	0,92	8	neutral	0,97	neutral	0,19	deleterious	2	deleterious	0,86	low_impact	-2,19	medium_impact	0,06	high_impact	2,35	0,72	0,85	52,04	12,37	P	0,67	P	0,98	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10648	10648	C	A	MI.16071	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	179	60	P	H	cCt/cAt	4,44	0,99	0	probably_damaging	0,99	neutral	0,54	neutral	1,85	deleterious	-3,53	deleterious	-8,8	high_impact	4,16	neutral	0,66	damaging	0,27	deleterious	3,88	23,5	0,16	0,45	disease	0,68	disease	0,96	disease	0,84	disease	0,92	8	deleterious	0,99	neutral	0,28	deleterious	2	deleterious	0,86	low_impact	-2,63	medium_impact	0,25	high_impact	2,35	0,75	0,85	52,04	12,37	P	0,62	P	0,91	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10650	10650	A	T	MI.16072	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	181	61	I	F	Att/Ttt	-20	0	0	possibly_damaging	0,68	neutral	0,8	neutral	1,79	neutral	-2,05	deleterious	-3,27	medium_impact	2,15	neutral	0,74	neutral	0,44	deleterious	3,74	23,3	0,25	0,45	neutral	0,43	disease	0,83	disease	0,53	disease	0,76	5	neutral	0,62	deleterious	0,56	NA	0	deleterious	0,58	low_impact	-1,1	medium_impact	0,54	medium_impact	0,66	0,71	0,85	29,59	10,13	N	0,26	N	0,88	disease_causing	0,5	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10650	10650	A	G	MI.16073	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	181	61	I	V	Att/Gtt	-20	0	0	benign	0,02	neutral	0,66	neutral	1,83	neutral	-1,43	neutral	-0,78	medium_impact	2,1	neutral	0,87	neutral	0,91	neutral	-0,15	1,38	0,35	0,5	neutral	0,27	neutral	0,4	neutral	0,35	neutral	0,45	1	neutral	0,3	deleterious	0,82	neutral	-3	neutral	0,11	medium_impact	0,75	medium_impact	0,37	medium_impact	0,62	0,52	0,8	29,59	10,13	N	0,37	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10650	10650	A	C	MI.16074	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	181	61	I	L	Att/Ctt	-20	0	0	benign	0,02	neutral	0,9	neutral	2,6	neutral	1,96	neutral	-0,93	neutral_impact	0,12	neutral	0,81	neutral	0,95	deleterious	0,31	5,75	0,27	0,45	neutral	0,13	neutral	0,47	neutral	0,24	neutral	0,45	1	neutral	0,05	deleterious	0,94	neutral	-6	neutral	0,13	medium_impact	0,75	medium_impact	0,74	low_impact	-1,04	0,55	0,8	29,59	10,13	N	0,35	N	0,45	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10651	10651	T	A	MI.16075	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	182	61	I	N	aTt/aAt	0,29	0,01	0	possibly_damaging	0,81	deleterious	0,04	neutral	1,73	deleterious	-4,39	deleterious	-6,03	high_impact	3,82	neutral	0,78	neutral	0,35	deleterious	4,17	23,8	0,28	0,45	disease	0,71	disease	0,86	disease	0,54	disease	0,78	6	neutral	0,97	neutral	0,12	deleterious	5	deleterious	0,67	low_impact	-1,38	medium_impact	-0,56	high_impact	2,06	0,56	0,8	29,59	10,13	N	0,39	N	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10651	10651	T	G	MI.16076	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	182	61	I	S	aTt/aGt	0,29	0,01	0	possibly_damaging	0,57	neutral	0,15	neutral	1,74	deleterious	-3,65	deleterious	-5,03	high_impact	3,82	neutral	0,71	neutral	0,31	deleterious	3,85	23,4	0,26	0,45	disease	0,54	disease	0,86	disease	0,61	disease	0,78	6	neutral	0,85	neutral	0,29	deleterious	1	deleterious	0,44	medium_impact	-0,92	medium_impact	-0,21	high_impact	2,06	0,5	0,8	29,59	10,13	N	0,43	N	0,93	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10651	10651	T	C	MI.16077	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	182	61	I	T	aTt/aCt	0,29	0,01	0	benign	0,09	neutral	0,47	neutral	1,76	deleterious	-3,09	deleterious	-4,04	medium_impact	3,02	neutral	0,92	neutral	0,72	neutral	1,41	12,85	0,38	0,5	neutral	0,47	disease	0,72	disease	0,52	disease	0,61	2	neutral	0,46	deleterious	0,69	neutral	-3	neutral	0,19	medium_impact	0,12	medium_impact	0,18	medium_impact	1,39	0,52	0,8	29,59	10,13	N	0,37	N	0,89	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10652	10652	T	G	MI.16078	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	183	61	I	M	atT/atG	4,67	0,7	0	benign	0,15	neutral	1	neutral	1,83	neutral	-1,41	neutral	-1,74	low_impact	1,5	neutral	0,81	neutral	0,83	neutral	-0,38	0,44	0,32	0,5	neutral	0,22	neutral	0,18	neutral	0,2	neutral	0,29	4	neutral	0,15	deleterious	0,93	neutral	-6	neutral	0,14	medium_impact	-0,11	high_impact	1,88	medium_impact	0,12	0,66	0,8	29,59	10,13	N	0,35	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10652	10652	T	A	MI.16079	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	183	61	I	M	atT/atA	4,67	0,7	0	benign	0,15	neutral	1	neutral	1,83	neutral	-1,41	neutral	-1,74	low_impact	1,5	neutral	0,81	neutral	0,83	neutral	-0,09	1,79	0,32	0,5	neutral	0,22	neutral	0,18	neutral	0,2	neutral	0,29	4	neutral	0,15	deleterious	0,93	neutral	-6	neutral	0,14	medium_impact	-0,11	high_impact	1,88	medium_impact	0,12	0,66	0,8	29,59	10,13	N	0,36	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8442	8442	T	A	MI.1608	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	77	26	L	Q	cTa/cAa	-1,03	0	0	probably_damaging	1	neutral	0,26	neutral	1,04	deleterious	-7,24	deleterious	-5,99	medium_impact	3,34	neutral	0,97	damaging	0,07	deleterious	4,09	23,7	0,21870687	0,85	disease	0,87	disease	0,68	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	0,04	medium_impact	1,77	0,66	0,85	1,47	7,57	N	0,41	N	0,91	polymorphism	0,94	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10653	10653	G	A	MI.16080	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	184	62	A	T	Gcc/Acc	-6,16	0	0	benign	0	neutral	0,27	neutral	2,37	neutral	2,88	neutral	0,74	neutral_impact	-0,77	neutral	0,88	neutral	0,98	deleterious	0,87	9,89	0,24	0,45	neutral	0,11	neutral	0,31	neutral	0,24	neutral	0,44	1	neutral	0,73	deleterious	0,64	neutral	-6	neutral	0,11	medium_impact	1,95	medium_impact	-0,03	low_impact	-1,78	0,57	0,8	27,55	13,3	N	0,34	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10653	10653	G	C	MI.16081	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	184	62	A	P	Gcc/Ccc	-6,16	0	0	possibly_damaging	0,64	neutral	0,05	neutral	1,94	neutral	-2,37	neutral	-2,06	low_impact	0,9	neutral	0,67	neutral	0,52	deleterious	3,45	23	0,19	0,45	neutral	0,45	disease	0,85	disease	0,62	disease	0,83	7	neutral	0,95	neutral	0,21	neutral	-3	deleterious	0,59	low_impact	-1,03	medium_impact	-0,5	medium_impact	-0,38	0,77	0,85	27,55	13,3	N	0,33	N	0,27	polymorphism	1	0,03	rs386829108	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10653	10653	G	T	MI.16082	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	184	62	A	S	Gcc/Tcc	-6,16	0	0	benign	0,17	neutral	0,44	neutral	1,98	neutral	-0,52	neutral	-0,86	low_impact	0,9	neutral	0,78	neutral	0,72	deleterious	1,88	15,49	0,27	0,45	neutral	0,25	neutral	0,46	neutral	0,46	neutral	0,48	0	neutral	0,47	deleterious	0,64	neutral	-6	neutral	0,22	medium_impact	-0,17	medium_impact	0,15	medium_impact	-0,38	0,75	0,85	27,55	13,3	N	0,31	N	0,12	polymorphism	1	0,02	rs386829108	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10654	10654	C	G	MI.16083	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	185	62	A	G	gCc/gGc	-0,86	0	0,01	benign	0,25	neutral	0,2	neutral	1,97	neutral	-0,74	deleterious	-2,85	low_impact	1,24	neutral	0,76	neutral	0,61	deleterious	2,22	17,65	0,18	0,45	neutral	0,38	disease	0,56	neutral	0,48	disease	0,54	1	neutral	0,76	deleterious	0,48	neutral	-6	neutral	0,28	medium_impact	-0,37	medium_impact	-0,12	medium_impact	-0,1	0,72	0,85	27,55	13,3	N	0,37	N	0,33	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10654	10654	C	T	MI.16084	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	185	62	A	V	gCc/gTc	-0,86	0	0,01	benign	0,01	neutral	0,62	neutral	2,09	neutral	1,21	neutral	2,11	neutral_impact	-1,94	neutral	0,88	neutral	0,98	neutral	1,09	11,18	0,28	0,45	neutral	0,11	neutral	0,42	neutral	0,28	neutral	0,45	1	neutral	0,36	deleterious	0,81	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,33	low_impact	-2,76	0,75	0,85	27,55	13,3	N	0,22	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10654	10654	C	A	MI.16085	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	185	62	A	D	gCc/gAc	-0,86	0	0,01	possibly_damaging	0,45	neutral	0,05	neutral	1,94	neutral	-2,98	neutral	-2,37	low_impact	1,24	neutral	0,72	neutral	0,43	deleterious	4,08	23,7	0,21	0,45	disease	0,5	disease	0,8	disease	0,63	disease	0,79	6	neutral	0,94	neutral	0,3	neutral	-3	deleterious	0,52	medium_impact	-0,72	medium_impact	-0,5	medium_impact	-0,1	0,71	0,85	27,55	13,3	N	0,32	N	0,3	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10656	10656	A	T	MI.16086	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	187	63	M	L	Ata/Tta	-8,7	0	0	benign	0	neutral	1	neutral	2,16	neutral	1,63	neutral	1,52	neutral_impact	-1,59	neutral	0,85	neutral	0,98	neutral	-1,11	0,01	0,38	0,5	neutral	0,14	neutral	0,41	neutral	0,39	neutral	0,44	1	neutral	0	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,95	high_impact	1,88	low_impact	-2,47	0,52	0,8	22,45	12,13	N	0,26	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10656	10656	A	C	MI.16087	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	187	63	M	L	Ata/Cta	-8,7	0	0	benign	0	neutral	1	neutral	2,16	neutral	1,63	neutral	1,52	neutral_impact	-1,59	neutral	0,85	neutral	0,98	neutral	-1,26	0,01	0,38	0,5	neutral	0,14	neutral	0,41	neutral	0,39	neutral	0,44	1	neutral	0	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,95	high_impact	1,88	low_impact	-2,47	0,52	0,8	22,45	12,13	N	0,26	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10656	10656	A	G	MI.16088	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	187	63	M	V	Ata/Gta	-8,7	0	0	benign	0,01	neutral	0,29	neutral	2,09	neutral	1,08	neutral	-0,65	low_impact	0,86	neutral	0,78	neutral	0,77	deleterious	0,88	9,96	0,37	0,5	neutral	0,2	disease	0,78	neutral	0,47	disease	0,6	2	neutral	0,71	deleterious	0,64	neutral	-6	neutral	0,16	medium_impact	1,03	medium_impact	-0,01	medium_impact	-0,42	0,56	0,8	22,45	12,13	N	0,31	N	0,16	polymorphism	1	0,02	rs28645634	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10657	10657	T	C	MI.16089	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	188	63	M	T	aTa/aCa	-1,55	0	0,01	benign	0,03	neutral	0,1	neutral	1,99	neutral	-0,22	deleterious	-2,86	medium_impact	2,52	neutral	0,82	neutral	0,73	neutral	1,07	11,04	0,34	0,5	neutral	0,33	disease	0,79	disease	0,64	disease	0,73	5	neutral	0,9	deleterious	0,54	neutral	-3	neutral	0,22	medium_impact	0,58	medium_impact	-0,32	medium_impact	0,97	0,37	0,8	22,45	12,13	N	0,37	N	0,47	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8444	8444	A	C	MI.1609	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	79	27	K	Q	Aaa/Caa	-2,88	0	0	probably_damaging	0,95	neutral	0,29	neutral	1,58	neutral	-0,21	deleterious	-3,98	medium_impact	3,23	neutral	0,97	damaging	0,13	deleterious	3,33	22,9	0,56366462	0,85	disease	0,66	disease	0,6	disease	0,69	disease	0,66	3	neutral	0,96	neutral	0,17	deleterious	1	deleterious	0,8	low_impact	-1,97	medium_impact	0,07	medium_impact	1,67	0,76	0,85	NA	NA	N	0,39	N	0,8	polymorphism	0,97	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10657	10657	T	A	MI.16090	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	188	63	M	K	aTa/aAa	-1,55	0	0,01	benign	0,04	deleterious	0,03	neutral	1,94	neutral	-2,03	deleterious	-3,98	medium_impact	2,52	neutral	0,75	neutral	0,41	deleterious	2,1	16,83	0,24	0,45	disease	0,52	disease	0,94	disease	0,71	disease	0,87	7	neutral	0,97	deleterious	0,5	deleterious	1	neutral	0,32	medium_impact	0,46	medium_impact	-0,63	medium_impact	0,97	0,54	0,8	22,45	12,13	N	0,32	N	0,67	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10658	10658	A	C	MI.16091	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	189	63	M	I	atA/atC	7,44	0,95	0,01	benign	0	neutral	0,27	neutral	2,11	neutral	1,31	neutral	0,27	neutral_impact	-0,24	neutral	0,77	neutral	0,99	deleterious	0,31	5,8	0,33	0,5	neutral	0,16	disease	0,77	neutral	0,44	disease	0,6	2	neutral	0,73	deleterious	0,64	neutral	-6	neutral	0,17	medium_impact	1,95	medium_impact	-0,03	low_impact	-1,34	0,59	0,8	22,45	12,13	N	0,45	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10658	10658	A	T	MI.16092	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	189	63	M	I	atA/atT	7,44	0,95	0,01	benign	0	neutral	0,27	neutral	2,11	neutral	1,31	neutral	0,27	neutral_impact	-0,24	neutral	0,77	neutral	0,99	deleterious	0,37	6,38	0,33	0,5	neutral	0,16	disease	0,77	neutral	0,44	disease	0,6	2	neutral	0,73	deleterious	0,64	neutral	-6	neutral	0,17	medium_impact	1,95	medium_impact	-0,03	low_impact	-1,34	0,59	0,8	22,45	12,13	N	0,45	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10659	10659	C	G	MI.16093	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	190	64	L	V	Cta/Gta	-5,24	0	0	possibly_damaging	0,9	neutral	0,38	neutral	1,39	neutral	-2,75	deleterious	-2,89	high_impact	4,01	neutral	0,63	damaging	0,08	deleterious	3,38	23	0,2	0,45	disease	0,5	disease	0,82	disease	0,74	disease	0,76	5	neutral	0,9	neutral	0,24	deleterious	1	deleterious	0,76	low_impact	-1,68	medium_impact	0,09	high_impact	2,22	0,72	0,85	53,06	11,99	N	0,35	N	0,75	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10659	10659	C	A	MI.16094	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	190	64	L	M	Cta/Ata	-5,24	0	0	possibly_damaging	0,76	neutral	0,13	neutral	1,32	deleterious	-3,88	neutral	-1,77	medium_impact	3,42	neutral	0,69	damaging	0,25	deleterious	3,53	23,1	0,2	0,45	disease	0,62	disease	0,78	disease	0,56	disease	0,65	3	neutral	0,91	neutral	0,19	NA	0	deleterious	0,71	low_impact	-1,26	medium_impact	-0,25	medium_impact	1,73	0,68	0,85	53,06	11,99	N	0,35	N	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10660	10660	T	A	MI.16095	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	191	64	L	Q	cTa/cAa	-0,63	0	0	probably_damaging	0,99	neutral	0,06	neutral	1,26	deleterious	-7,61	deleterious	-5,79	high_impact	4,7	damaging	0,57	damaging	0,07	deleterious	4,36	24,1	0,13	0,4	disease	0,85	disease	0,93	disease	0,75	disease	0,86	7	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,87	low_impact	-2,63	medium_impact	-0,45	high_impact	2,8	0,61	0,8	53,06	11,99	P	0,51	P	0,99	disease_causing	0,99	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10660	10660	T	C	MI.16096	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	191	64	L	P	cTa/cCa	-0,63	0	0	probably_damaging	1	deleterious	0,03	neutral	1,26	deleterious	-7,93	deleterious	-6,82	high_impact	4,7	damaging	0,45	damaging	0,05	deleterious	3,95	23,6	0,12	0,4	disease	0,88	disease	0,94	disease	0,82	disease	0,92	8	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,89	low_impact	-3,55	medium_impact	-0,63	high_impact	2,8	0,47	0,8	53,06	11,99	P	0,51	P	1	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10660	10660	T	G	MI.16097	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	191	64	L	R	cTa/cGa	-0,63	0	0	probably_damaging	0,99	deleterious	0,04	neutral	1,26	deleterious	-7,65	deleterious	-5,83	high_impact	4,7	damaging	0,53	damaging	0,05	deleterious	4,2	23,9	0,12	0,4	disease	0,84	disease	0,96	disease	0,83	disease	0,92	8	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,91	low_impact	-2,63	medium_impact	-0,56	high_impact	2,8	0,43	0,8	53,06	11,99	P	0,51	P	0,99	disease_causing	0,99	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10662	10662	G	C	MI.16098	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	193	65	V	L	Gtc/Ctc	-0,4	0,17	0	benign	0,12	neutral	0,74	neutral	1,47	deleterious	-3,07	deleterious	-2,85	medium_impact	3,42	neutral	0,77	neutral	0,39	neutral	1,69	14,36	0,38	0,5	neutral	0,38	disease	0,8	disease	0,54	disease	0,76	5	neutral	0,15	deleterious	0,81	neutral	-3	neutral	0,26	medium_impact	-0,01	medium_impact	0,46	medium_impact	1,73	0,64	0,8	54,08	12,24	N	0,25	N	0,87	polymorphism	0,86	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10662	10662	G	T	MI.16099	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	193	65	V	F	Gtc/Ttc	-0,4	0,17	0	probably_damaging	0,92	neutral	0,77	neutral	1,41	deleterious	-4,43	deleterious	-4,84	medium_impact	3,27	neutral	0,66	neutral	0,41	deleterious	3,79	23,4	0,25	0,45	disease	0,59	disease	0,94	disease	0,6	disease	0,82	6	neutral	0,9	neutral	0,43	deleterious	1	deleterious	0,8	low_impact	-1,78	medium_impact	0,5	medium_impact	1,6	0,49	0,8	54,08	12,24	N	0,3	N	0,96	disease_causing	0,64	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8602	8602	T	C	MI.161	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	76	26	F	L	Ttt/Ctt	-2,65	0	0,01	benign	0	neutral	1	neutral	4,49	neutral	0,67	neutral	-1,96	neutral_impact	-0,38	neutral	0,96	neutral	0,92	neutral	-0,82	0,04	0,42	0,65	neutral	0,29	neutral	0,15	neutral	0,27	neutral	0,22	6	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,09	high_impact	1,98	low_impact	-1,42	0,39	0,9	15,49	8,03	N	0,32	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8444	8444	A	G	MI.1610	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	79	27	K	E	Aaa/Gaa	-2,88	0	0	possibly_damaging	0,87	neutral	0,27	neutral	1,58	neutral	-0,34	deleterious	-3,98	high_impact	3,92	neutral	0,83	damaging	0,13	deleterious	3,88	23,5	0,28300158	0,85	disease	0,66	disease	0,62	disease	0,75	disease	0,68	4	neutral	0,9	neutral	0,2	deleterious	1	deleterious	0,81	low_impact	-1,54	medium_impact	0,05	high_impact	2,26	0,66	0,85	NA	NA	N	0,4	N	0,86	polymorphism	0,96	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10662	10662	G	A	MI.16100	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	193	65	V	I	Gtc/Atc	-0,4	0,17	0	benign	0,2	neutral	0,42	neutral	1,47	deleterious	-3,04	neutral	-0,86	medium_impact	2,62	neutral	0,76	neutral	0,54	deleterious	0,71	8,87	0,38	0,5	neutral	0,38	disease	0,7	neutral	0,48	disease	0,53	1	neutral	0,49	deleterious	0,61	neutral	-3	neutral	0,29	medium_impact	-0,25	medium_impact	0,13	medium_impact	1,06	0,79	0,85	54,08	12,24	N	0,33	N	0,8	polymorphism	0,95	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10663	10663	T	C	MI.16101	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	194	65	V	A	gTc/gCc	0,98	0,75	0	possibly_damaging	0,8	neutral	0,62	neutral	1,53	neutral	-2,23	deleterious	-3,98	medium_impact	2,15	damaging	0,28	damaging	0,25	neutral	1,28	12,18	0,43	0,55	neutral	0,19	neutral	0,28	neutral	0,36	neutral	0,43	1	neutral	0,77	neutral	0,41	NA	0	deleterious	0,58	low_impact	-1,35	medium_impact	0,33	medium_impact	0,66	0,33	0,8	54,08	12,24	P	0,9	P	0,89	disease_causing_automatic	0,12	0,1	rs193302933	Pathogenic	Leber's_optic_atrophy	RCV000010353.3	MedGen:OMIM:SNOMED_CT	.	.	.	.	T10663C	LHON	+	-	Cfrm	9
chrM	10663	10663	T	A	MI.16102	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	194	65	V	D	gTc/gAc	0,98	0,75	0	probably_damaging	0,98	neutral	0,2	neutral	1,39	deleterious	-6,18	deleterious	-6,89	high_impact	3,97	neutral	0,7	neutral	0,37	deleterious	4,68	24,6	0,11	0,4	disease	0,65	disease	0,94	disease	0,7	disease	0,86	7	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-2,35	medium_impact	-0,12	high_impact	2,19	0,53	0,8	54,08	12,24	N	0,42	N	0,98	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10663	10663	T	G	MI.16103	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	194	65	V	G	gTc/gGc	0,98	0,75	0	probably_damaging	0,97	neutral	0,36	neutral	1,4	deleterious	-4,9	deleterious	-6,96	medium_impact	2,82	neutral	0,74	neutral	0,45	deleterious	3,8	23,4	0,27	0,45	disease	0,52	disease	0,91	disease	0,57	disease	0,79	6	neutral	0,97	neutral	0,2	deleterious	1	deleterious	0,79	low_impact	-2,19	medium_impact	0,07	medium_impact	1,23	0,5	0,8	54,08	12,24	N	0,35	N	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10665	10665	T	G	MI.16104	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	196	66	F	V	Ttt/Gtt	-2,71	0	0	benign	0,36	neutral	0,45	neutral	1,99	neutral	0,59	deleterious	-6,8	medium_impact	2,68	neutral	0,74	neutral	0,45	deleterious	2,33	18,35	0,21	0,45	disease	0,52	disease	0,95	disease	0,67	disease	0,82	6	neutral	0,47	deleterious	0,55	neutral	-3	neutral	0,41	medium_impact	-0,57	medium_impact	0,16	medium_impact	1,11	0,43	0,8	55,1	11,43	N	0,28	N	0,9	disease_causing	0,81	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10665	10665	T	A	MI.16105	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	196	66	F	I	Ttt/Att	-2,71	0	0	benign	0,11	neutral	0,38	neutral	2,25	neutral	-0,7	deleterious	-5,81	medium_impact	2,94	neutral	0,77	neutral	0,65	deleterious	2,46	19,19	0,34	0,5	disease	0,55	disease	0,93	disease	0,53	disease	0,6	2	neutral	0,56	deleterious	0,64	neutral	-3	neutral	0,31	medium_impact	0,03	medium_impact	0,09	medium_impact	1,33	0,49	0,8	55,1	11,43	N	0,31	N	0,66	disease_causing	0,66	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10665	10665	T	C	MI.16106	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	196	66	F	L	Ttt/Ctt	-2,71	0	0	benign	0,08	neutral	0,75	neutral	1,97	neutral	-0,18	deleterious	-5,77	low_impact	1,84	neutral	0,81	neutral	0,71	deleterious	2,05	16,5	0,53	0,6	neutral	0,45	disease	0,81	neutral	0,47	disease	0,57	1	neutral	0,15	deleterious	0,84	neutral	-6	neutral	0,25	medium_impact	0,17	medium_impact	0,48	medium_impact	0,4	0,47	0,8	55,1	11,43	N	0,21	N	0,89	disease_causing	0,69	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10666	10666	T	A	MI.16107	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	197	66	F	Y	tTt/tAt	5,6	1	0	possibly_damaging	0,89	neutral	0,71	neutral	1,79	deleterious	-3,61	deleterious	-2,94	high_impact	4,11	neutral	0,75	neutral	0,43	deleterious	4,17	23,8	0,25	0,45	disease	0,54	disease	0,93	disease	0,65	disease	0,76	5	neutral	0,87	neutral	0,41	deleterious	1	deleterious	0,74	low_impact	-1,64	medium_impact	0,43	high_impact	2,31	0,51	0,8	55,1	11,43	P	0,63	P	0,85	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10666	10666	T	G	MI.16108	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	197	66	F	C	tTt/tGt	5,6	1	0	probably_damaging	0,98	neutral	0,17	neutral	1,78	deleterious	-4,48	deleterious	-7,82	high_impact	4,46	neutral	0,68	neutral	0,41	deleterious	4,09	23,7	0,2	0,45	disease	0,83	disease	0,95	disease	0,71	disease	0,85	7	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-2,35	medium_impact	-0,17	high_impact	2,6	0,31	0,8	55,1	11,43	P	0,7	P	0,96	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10666	10666	T	C	MI.16109	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	197	66	F	S	tTt/tCt	5,6	1	0	probably_damaging	0,93	neutral	0,46	neutral	1,81	deleterious	-3,48	deleterious	-7,83	high_impact	4,11	neutral	0,75	neutral	0,46	deleterious	4,17	23,8	0,18	0,45	disease	0,6	disease	0,96	disease	0,66	disease	0,82	6	neutral	0,92	neutral	0,27	deleterious	2	deleterious	0,8	low_impact	-1,83	medium_impact	0,17	high_impact	2,31	0,37	0,8	55,1	11,43	P	0,66	P	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8445	8445	A	C	MI.1611	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	80	27	K	T	aAa/aCa	8,46	1	0	probably_damaging	0,92	neutral	0,4	neutral	1,59	neutral	1,25	deleterious	-5,98	high_impact	3,58	neutral	0,95	damaging	0,13	deleterious	3,3	22,9	0,18580261	0,85	disease	0,75	disease	0,51	disease	0,73	disease	0,65	3	neutral	0,92	neutral	0,24	deleterious	2	deleterious	0,81	low_impact	-1,76	medium_impact	0,19	medium_impact	1,97	0,63	0,85	NA	NA	P	0,64	P	0,81	disease_causing	0,96	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10667	10667	T	A	MI.16110	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	198	66	F	L	ttT/ttA	7,44	1	0	benign	0,08	neutral	0,75	neutral	1,97	neutral	-0,18	deleterious	-5,77	low_impact	1,84	neutral	0,81	neutral	0,71	deleterious	2,52	19,56	0,53	0,6	neutral	0,45	disease	0,81	neutral	0,47	disease	0,57	1	neutral	0,15	deleterious	0,84	neutral	-6	neutral	0,25	medium_impact	0,17	medium_impact	0,48	medium_impact	0,4	0,47	0,8	55,1	11,43	N	0,52	P	0,89	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10667	10667	T	G	MI.16111	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	198	66	F	L	ttT/ttG	7,44	1	0	benign	0,08	neutral	0,75	neutral	1,97	neutral	-0,18	deleterious	-5,77	low_impact	1,84	neutral	0,81	neutral	0,71	deleterious	2,38	18,72	0,53	0,6	neutral	0,45	disease	0,81	neutral	0,47	disease	0,57	1	neutral	0,15	deleterious	0,84	neutral	-6	neutral	0,25	medium_impact	0,17	medium_impact	0,48	medium_impact	0,4	0,47	0,8	55,1	11,43	N	0,52	P	0,89	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10668	10668	G	A	MI.16112	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	199	67	A	T	Gcc/Acc	-4,32	0	0	benign	0,28	neutral	0,48	neutral	1,74	neutral	-2,84	deleterious	-3,48	medium_impact	2,98	neutral	0,81	neutral	0,64	deleterious	4,16	23,8	0,49	0,55	neutral	0,47	disease	0,82	disease	0,59	disease	0,75	5	neutral	0,42	deleterious	0,6	neutral	-3	deleterious	0,78	medium_impact	-0,43	medium_impact	0,19	medium_impact	1,36	0,75	0,85	53,06	9,88	N	0,29	N	0,7	polymorphism	0,75	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10668	10668	G	T	MI.16113	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	199	67	A	S	Gcc/Tcc	-4,32	0	0	possibly_damaging	0,64	neutral	0,68	neutral	1,88	neutral	-1,4	neutral	-2,38	neutral_impact	0,46	neutral	0,75	neutral	0,87	deleterious	0,75	9,15	0,49	0,55	neutral	0,12	neutral	0,22	neutral	0,33	neutral	0,38	2	neutral	0,57	deleterious	0,52	neutral	-3	deleterious	0,52	low_impact	-1,03	medium_impact	0,39	medium_impact	-0,75	0,65	0,8	53,06	9,88	N	0,32	N	0,45	polymorphism	0,87	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10668	10668	G	C	MI.16114	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	199	67	A	P	Gcc/Ccc	-4,32	0	0	benign	0,17	neutral	0,21	neutral	1,68	deleterious	-4,86	deleterious	-4,26	high_impact	4,08	damaging	0,57	neutral	0,36	deleterious	1,89	15,55	0,17	0,45	disease	0,68	disease	0,97	disease	0,7	disease	0,88	8	neutral	0,75	deleterious	0,52	neutral	-2	neutral	0,39	medium_impact	-0,17	medium_impact	-0,11	high_impact	2,28	0,61	0,8	53,06	9,88	N	0,37	N	0,88	disease_causing	0,54	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10669	10669	C	A	MI.16115	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	200	67	A	D	gCc/gAc	3,52	1	0	probably_damaging	0,93	neutral	0,21	neutral	1,71	deleterious	-5,06	deleterious	-5,31	high_impact	4,08	neutral	0,64	neutral	0,29	deleterious	4,45	24,2	0,21	0,45	disease	0,71	disease	0,96	disease	0,68	disease	0,85	7	neutral	0,95	neutral	0,14	deleterious	2	deleterious	0,85	low_impact	-1,83	medium_impact	-0,11	high_impact	2,28	0,52	0,8	53,06	9,88	P	0,58	P	0,98	disease_causing	0,99	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10669	10669	C	T	MI.16116	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	200	67	A	V	gCc/gTc	3,52	1	0	possibly_damaging	0,75	neutral	0,68	neutral	1,71	deleterious	-3,38	deleterious	-3,77	medium_impact	2,66	neutral	0,72	neutral	0,55	deleterious	4,45	24,2	0,59	0,65	disease	0,6	disease	0,9	disease	0,59	disease	0,78	6	neutral	0,7	neutral	0,47	NA	0	deleterious	0,8	low_impact	-1,24	medium_impact	0,39	medium_impact	1,09	0,73	0,85	53,06	9,88	N	0,52	P	0,89	disease_causing	0,96	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10669	10669	C	G	MI.16117	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	200	67	A	G	gCc/gGc	3,52	1	0	benign	0,08	neutral	0,41	neutral	1,95	deleterious	-3,78	deleterious	-3,52	medium_impact	2,12	neutral	0,83	neutral	0,68	deleterious	2,04	16,44	0,36	0,5	disease	0,51	disease	0,89	neutral	0,43	disease	0,61	2	neutral	0,54	deleterious	0,67	neutral	-3	neutral	0,3	medium_impact	0,17	medium_impact	0,12	medium_impact	0,64	0,72	0,85	53,06	9,88	N	0,52	P	0,62	disease_causing	0,95	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10671	10671	G	T	MI.16118	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	202	68	A	S	Gcc/Tcc	-11,01	0	0	probably_damaging	0,92	neutral	0,22	neutral	1,55	deleterious	-3,49	deleterious	-2,79	high_impact	4,57	neutral	0,63	neutral	0,39	deleterious	3,64	23,2	0,4	0,5	neutral	0,49	disease	0,94	disease	0,65	disease	0,81	6	neutral	0,95	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-1,78	medium_impact	-0,1	high_impact	2,69	0,65	0,8	53,06	12,04	N	0,54	P	0,82	polymorphism	0,83	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10671	10671	G	A	MI.16119	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	202	68	A	T	Gcc/Acc	-11,01	0	0	probably_damaging	0,97	neutral	0,18	neutral	1,56	deleterious	-3,87	deleterious	-3,78	high_impact	4,22	neutral	0,65	neutral	0,31	deleterious	4,23	23,9	0,42	0,5	disease	0,52	disease	0,93	disease	0,66	disease	0,77	5	neutral	0,98	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-2,19	medium_impact	-0,16	high_impact	2,4	0,65	0,8	53,06	12,04	N	0,46	N	0,94	polymorphism	0,69	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8445	8445	A	T	MI.1612	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	80	27	K	M	aAa/aTa	8,46	1	0	probably_damaging	0,98	neutral	0,26	neutral	1,79	neutral	5,13	deleterious	-5,98	high_impact	3,92	neutral	0,95	damaging	0,12	deleterious	3,62	23,2	0,1762827	0,85	disease	0,89	disease	0,52	disease	0,74	disease	0,66	3	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-2,36	medium_impact	0,04	high_impact	2,26	0,67	0,85	NA	NA	P	0,62	P	0,69	disease_causing	0,98	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10671	10671	G	C	MI.16120	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	202	68	A	P	Gcc/Ccc	-11,01	0	0	possibly_damaging	0,5	neutral	0,05	neutral	1,52	deleterious	-5,42	deleterious	-4,44	high_impact	4,22	damaging	0,59	neutral	0,36	deleterious	2,12	17	0,21	0,45	disease	0,75	disease	0,96	disease	0,73	disease	0,86	7	neutral	0,95	neutral	0,28	deleterious	1	deleterious	0,54	medium_impact	-0,8	medium_impact	-0,5	high_impact	2,4	0,65	0,8	53,06	12,04	N	0,4	N	0,88	disease_causing	0,62	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10672	10672	C	A	MI.16121	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	203	68	A	D	gCc/gAc	7,44	1	0	probably_damaging	0,98	neutral	0,07	neutral	1,52	deleterious	-5,48	deleterious	-5,61	high_impact	4,57	neutral	0,62	neutral	0,33	deleterious	4,56	24,4	0,16	0,45	disease	0,79	disease	0,97	disease	0,74	disease	0,88	8	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,89	low_impact	-2,35	medium_impact	-0,41	high_impact	2,69	0,59	0,8	53,06	12,04	P	0,66	P	0,96	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10672	10672	C	T	MI.16122	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	203	68	A	V	gCc/gTc	7,44	1	0	probably_damaging	0,98	neutral	0,38	neutral	1,75	neutral	-2,6	deleterious	-3,85	medium_impact	2,12	neutral	0,67	neutral	0,64	deleterious	4,52	24,3	0,5	0,6	neutral	0,19	disease	0,92	neutral	0,49	disease	0,56	1	neutral	0,98	neutral	0,2	deleterious	1	deleterious	0,76	low_impact	-2,35	medium_impact	0,09	medium_impact	0,64	0,61	0,8	53,06	12,04	P	0,56	P	0,88	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10672	10672	C	G	MI.16123	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	203	68	A	G	gCc/gGc	7,44	1	0	benign	0,3	neutral	0,14	neutral	1,55	deleterious	-3,69	deleterious	-3,54	high_impact	4,57	neutral	0,72	neutral	0,56	deleterious	2,24	17,75	0,32	0,5	disease	0,61	disease	0,93	disease	0,65	disease	0,76	5	neutral	0,83	neutral	0,42	neutral	-2	deleterious	0,83	medium_impact	-0,47	medium_impact	-0,23	high_impact	2,69	0,78	0,85	53,06	12,04	P	0,69	P	0,81	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10674	10674	T	G	MI.16124	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	205	69	C	G	Tgc/Ggc	-10,08	0	0	probably_damaging	0,94	neutral	0,32	neutral	1,75	deleterious	-3,37	deleterious	-11,42	high_impact	4,12	neutral	0,64	neutral	0,4	deleterious	3,28	22,8	0,31	0,45	disease	0,68	disease	0,97	disease	0,7	disease	0,85	7	neutral	0,95	neutral	0,19	deleterious	2	deleterious	0,79	low_impact	-1,9	medium_impact	0,03	high_impact	2,32	0,35	0,8	54,08	12,17	N	0,46	N	0,9	disease_causing	0,98	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10674	10674	T	A	MI.16125	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	205	69	C	S	Tgc/Agc	-10,08	0	0	probably_damaging	0,96	neutral	0,35	neutral	1,82	neutral	-2,58	deleterious	-9,54	medium_impact	3,15	neutral	0,66	neutral	0,37	deleterious	3,66	23,2	0,38	0,5	disease	0,6	disease	0,97	disease	0,69	disease	0,81	6	neutral	0,96	neutral	0,2	deleterious	1	deleterious	0,83	low_impact	-2,07	medium_impact	0,06	medium_impact	1,5	0,41	0,8	54,08	12,17	N	0,37	N	0,78	disease_causing	0,97	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10674	10674	T	C	MI.16126	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	205	69	C	R	Tgc/Cgc	-10,08	0	0	probably_damaging	0,98	neutral	0,08	neutral	1,71	deleterious	-4,81	deleterious	-11,45	high_impact	4,32	damaging	0,56	damaging	0,24	deleterious	3,51	23,1	0,3	0,45	disease	0,84	disease	0,98	disease	0,78	disease	0,86	7	deleterious	0,99	neutral	0,05	deleterious	2	deleterious	0,9	low_impact	-2,35	medium_impact	-0,38	high_impact	2,48	0,26	0,8	54,08	12,17	N	0,51	P	0,92	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10675	10675	G	C	MI.16127	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	206	69	C	S	tGc/tCc	7,44	1	0	probably_damaging	0,96	neutral	0,35	neutral	1,82	neutral	-2,58	deleterious	-9,54	medium_impact	3,15	neutral	0,66	neutral	0,37	deleterious	3,2	22,7	0,38	0,5	disease	0,6	disease	0,97	disease	0,69	disease	0,81	6	neutral	0,96	neutral	0,2	deleterious	1	deleterious	0,83	low_impact	-2,07	medium_impact	0,06	medium_impact	1,5	0,41	0,8	54,08	12,17	P	0,57	P	0,78	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10675	10675	G	A	MI.16128	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	206	69	C	Y	tGc/tAc	7,44	1	0	probably_damaging	0,92	neutral	0,29	neutral	1,7	deleterious	-5,55	deleterious	-10,29	high_impact	4,67	neutral	0,64	damaging	0,25	deleterious	3,5	23,1	0,31	0,45	disease	0,9	disease	0,98	disease	0,73	disease	0,85	7	neutral	0,93	neutral	0,19	deleterious	2	deleterious	0,83	low_impact	-1,78	medium_impact	-0,01	high_impact	2,78	0,36	0,8	54,08	12,17	P	0,64	P	0,89	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10675	10675	G	T	MI.16129	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	206	69	C	F	tGc/tTc	7,44	1	0	probably_damaging	0,92	neutral	0,33	neutral	1,72	deleterious	-5,07	deleterious	-10,34	high_impact	4,67	neutral	0,64	damaging	0,26	deleterious	3,81	23,4	0,27	0,45	disease	0,87	disease	0,98	disease	0,73	disease	0,85	7	neutral	0,93	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-1,78	medium_impact	0,04	high_impact	2,78	0,36	0,8	54,08	12,17	P	0,64	P	0,93	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8446	8446	A	C	MI.1613	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	81	27	K	N	aaA/aaC	4,29	1	0	probably_damaging	0,95	neutral	0,36	neutral	1,58	neutral	-0,54	deleterious	-4,98	medium_impact	2,82	neutral	0,98	neutral	0,39	deleterious	3,66	23,2	0,56663707	0,85	disease	0,73	disease	0,54	disease	0,62	disease	0,61	2	neutral	0,95	neutral	0,21	deleterious	1	deleterious	0,82	low_impact	-1,97	medium_impact	0,15	medium_impact	1,32	0,6	0,85	NA	NA	P	0,62	P	0,71	disease_causing	0,9	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10676	10676	C	A	MI.16130	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	207	69	C	W	tgC/tgA	7,44	1	0,01	benign	0,12	neutral	0,06	neutral	1,68	deleterious	-7,2	deleterious	-10,01	high_impact	3,77	neutral	0,62	neutral	0,32	deleterious	2,63	20,4	0,22	0,45	disease	0,96	disease	0,98	disease	0,76	disease	0,83	7	neutral	0,93	deleterious	0,47	neutral	-2	neutral	0,39	medium_impact	-0,01	medium_impact	-0,45	high_impact	2,02	0,2	0,8	54,08	12,17	P	0,5	N	0,91	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10676	10676	C	G	MI.16131	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	207	69	C	W	tgC/tgG	7,44	1	0,01	benign	0,12	neutral	0,06	neutral	1,68	deleterious	-7,2	deleterious	-10,01	high_impact	3,77	neutral	0,62	neutral	0,32	deleterious	2,36	18,55	0,22	0,45	disease	0,96	disease	0,98	disease	0,76	disease	0,83	7	neutral	0,93	deleterious	0,47	neutral	-2	neutral	0,39	medium_impact	-0,01	medium_impact	-0,45	high_impact	2,02	0,2	0,8	54,08	12,17	N	0,49	N	0,91	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10677	10677	G	C	MI.16132	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	208	70	E	Q	Gaa/Caa	-5,47	0	0	probably_damaging	0,91	neutral	0,3	neutral	1,54	deleterious	-6,32	deleterious	-2,96	high_impact	4,73	damaging	0,54	neutral	0,48	deleterious	3,38	23	0,42	0,55	disease	0,79	disease	0,94	disease	0,71	disease	0,85	7	neutral	0,92	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-1,72	medium_impact	0,01	high_impact	2,83	0,65	0,8	52,04	12,46	P	0,67	P	0,84	disease_causing	0,94	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10677	10677	G	A	MI.16133	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	208	70	E	K	Gaa/Aaa	-5,47	0	0	benign	0,29	neutral	0,29	neutral	1,56	deleterious	-5,94	deleterious	-3,94	high_impact	4,73	damaging	0,48	neutral	0,3	deleterious	2,78	21,3	0,35	0,5	disease	0,75	disease	0,98	disease	0,75	disease	0,86	7	neutral	0,65	deleterious	0,5	neutral	-2	deleterious	0,46	medium_impact	-0,45	medium_impact	-0,01	high_impact	2,83	0,71	0,85	52,04	12,46	P	0,64	P	1	disease_causing	0,99	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10678	10678	A	G	MI.16134	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	209	70	E	G	gAa/gGa	4,44	1	0	probably_damaging	0,96	neutral	0,35	neutral	1,52	deleterious	-6,43	deleterious	-6,9	medium_impact	3,19	damaging	0,57	neutral	0,66	deleterious	4,27	23,9	0,32	0,5	disease	0,78	disease	0,94	disease	0,61	disease	0,61	2	neutral	0,96	neutral	0,2	deleterious	1	deleterious	0,87	low_impact	-2,07	medium_impact	0,06	medium_impact	1,54	0,28	0,8	52,04	12,46	P	0,53	P	0,73	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10678	10678	A	C	MI.16135	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	209	70	E	A	gAa/gCa	4,44	1	0	probably_damaging	0,91	neutral	0,53	neutral	1,58	deleterious	-6,2	deleterious	-5,9	high_impact	4,73	neutral	0,61	neutral	0,49	deleterious	3,72	23,3	0,23	0,45	disease	0,78	disease	0,93	disease	0,67	disease	0,76	5	neutral	0,9	neutral	0,31	deleterious	2	deleterious	0,83	low_impact	-1,72	medium_impact	0,24	high_impact	2,83	0,46	0,8	52,04	12,46	P	0,67	P	0,84	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10678	10678	A	T	MI.16136	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	209	70	E	V	gAa/gTa	4,44	1	0	probably_damaging	0,98	neutral	0,52	neutral	1,62	deleterious	-7,36	deleterious	-6,87	high_impact	4,73	neutral	0,61	neutral	0,44	deleterious	4,28	24	0,22	0,45	disease	0,88	disease	0,97	disease	0,71	disease	0,85	7	neutral	0,98	neutral	0,27	deleterious	2	deleterious	0,9	low_impact	-2,35	medium_impact	0,23	high_impact	2,83	0,42	0,8	52,04	12,46	P	0,67	P	0,89	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10679	10679	A	T	MI.16137	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	210	70	E	D	gaA/gaT	8,59	1	0	possibly_damaging	0,89	neutral	0,21	neutral	1,53	deleterious	-5,15	deleterious	-2,96	high_impact	4,04	neutral	0,63	neutral	0,47	deleterious	3,85	23,4	0,53	0,6	disease	0,63	disease	0,94	disease	0,61	disease	0,73	5	neutral	0,93	neutral	0,16	deleterious	1	deleterious	0,83	low_impact	-1,64	medium_impact	-0,11	high_impact	2,25	0,66	0,8	52,04	12,46	P	0,68	P	0,83	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10679	10679	A	C	MI.16138	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	210	70	E	D	gaA/gaC	8,59	1	0	possibly_damaging	0,89	neutral	0,21	neutral	1,53	deleterious	-5,15	deleterious	-2,96	high_impact	4,04	neutral	0,63	neutral	0,47	deleterious	3,73	23,3	0,53	0,6	disease	0,63	disease	0,94	disease	0,61	disease	0,73	5	neutral	0,93	neutral	0,16	deleterious	1	deleterious	0,83	low_impact	-1,64	medium_impact	-0,11	high_impact	2,25	0,66	0,8	52,04	12,46	P	0,68	P	0,83	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10680	10680	G	A	MI.16139	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	211	71	A	T	Gca/Aca	0,06	0,94	0,01	benign	0,05	neutral	0,09	neutral	1,94	neutral	-2,9	deleterious	-2,98	high_impact	3,99	neutral	0,72	neutral	0,6	deleterious	2,35	18,51	0,38	0,5	disease	0,5	disease	0,89	disease	0,59	disease	0,57	1	neutral	0,9	deleterious	0,52	neutral	-2	neutral	0,31	medium_impact	0,37	medium_impact	-0,35	high_impact	2,21	0,7	0,85	51,02	11,05	N	0,42	N	0,02	disease_causing	0,97	0,18	.	.	.	.	.	.	.	.	.	G10680A	LHON	+	-	Reported-possibly synergistic	2
chrM	8446	8446	A	T	MI.1614	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	81	27	K	N	aaA/aaT	4,29	1	0	probably_damaging	0,95	neutral	0,36	neutral	1,58	neutral	-0,54	deleterious	-4,98	medium_impact	2,82	neutral	0,98	neutral	0,39	deleterious	3,71	23,3	0,56663707	0,85	disease	0,73	disease	0,54	disease	0,62	disease	0,61	2	neutral	0,95	neutral	0,21	deleterious	1	deleterious	0,82	low_impact	-1,97	medium_impact	0,15	medium_impact	1,32	0,6	0,85	NA	NA	P	0,63	P	0,71	disease_causing	0,9	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10680	10680	G	T	MI.16140	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	211	71	A	S	Gca/Tca	0,06	0,94	0,01	possibly_damaging	0,64	neutral	0,25	neutral	1,76	neutral	-2,15	neutral	-2,47	medium_impact	2,92	neutral	0,65	neutral	0,39	deleterious	2,17	17,33	0,48	0,55	neutral	0,43	disease	0,94	disease	0,58	disease	0,77	5	neutral	0,77	neutral	0,31	NA	0	deleterious	0,68	low_impact	-1,03	medium_impact	-0,06	medium_impact	1,31	0,64	0,8	51,02	11,05	N	0,42	N	0,63	disease_causing	0,94	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10680	10680	G	C	MI.16141	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	211	71	A	P	Gca/Cca	0,06	0,94	0,01	probably_damaging	0,95	neutral	0,07	neutral	1,67	deleterious	-4,58	deleterious	-4,46	high_impact	4,54	damaging	0,56	neutral	0,29	deleterious	3,83	23,4	0,23	0,45	disease	0,71	disease	0,96	disease	0,75	disease	0,89	8	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,86	low_impact	-1,97	medium_impact	-0,41	high_impact	2,67	0,58	0,8	51,02	11,05	P	0,56	P	0,86	disease_causing	0,99	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10681	10681	C	T	MI.16142	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	212	71	A	V	gCa/gTa	5,13	1	0	possibly_damaging	0,75	neutral	0,27	neutral	1,77	neutral	-1,64	deleterious	-3,53	high_impact	4,2	neutral	0,65	neutral	0,29	deleterious	4,12	23,8	0,44	0,55	disease	0,61	disease	0,92	disease	0,63	disease	0,75	5	neutral	0,82	neutral	0,26	deleterious	1	deleterious	0,7	low_impact	-1,24	medium_impact	-0,03	high_impact	2,38	0,69	0,85	51,02	11,05	P	0,69	P	0,58	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10681	10681	C	G	MI.16143	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	212	71	A	G	gCa/gGa	5,13	1	0	benign	0,08	neutral	0,51	neutral	1,72	neutral	-2,09	deleterious	-3,44	low_impact	1,84	neutral	0,67	neutral	0,46	deleterious	2,04	16,46	0,4	0,5	neutral	0,21	disease	0,92	neutral	0,44	disease	0,73	5	neutral	0,42	deleterious	0,72	neutral	-6	neutral	0,23	medium_impact	0,17	medium_impact	0,22	medium_impact	0,4	0,73	0,85	51,02	11,05	P	0,55	P	0,63	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10681	10681	C	A	MI.16144	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	212	71	A	E	gCa/gAa	5,13	1	0	possibly_damaging	0,87	neutral	0,26	neutral	1,7	deleterious	-3,8	deleterious	-4,46	high_impact	4,54	neutral	0,61	neutral	0,36	deleterious	4,4	24,1	0,17	0,45	disease	0,6	disease	0,95	disease	0,71	disease	0,86	7	neutral	0,9	neutral	0,2	deleterious	1	deleterious	0,82	low_impact	-1,56	medium_impact	-0,04	high_impact	2,67	0,51	0,8	51,02	11,05	P	0,7	P	0,84	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10683	10683	G	C	MI.16145	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	214	72	A	P	Gcg/Ccg	-4,32	0	0	probably_damaging	0,97	neutral	0,23	neutral	1,36	deleterious	-5,83	deleterious	-4,75	high_impact	4,27	neutral	0,61	neutral	0,29	deleterious	3,9	23,5	0,24	0,45	disease	0,7	disease	0,94	disease	0,71	disease	0,88	8	deleterious	0,98	neutral	0,13	deleterious	2	deleterious	0,86	low_impact	-2,19	medium_impact	-0,08	high_impact	2,44	0,62	0,8	51,02	9,95	N	0,4	N	0,86	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10683	10683	G	A	MI.16146	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	214	72	A	T	Gcg/Acg	-4,32	0	0	probably_damaging	0,95	neutral	0,45	neutral	1,41	deleterious	-3,76	deleterious	-3,82	medium_impact	3,3	neutral	0,73	neutral	0,48	deleterious	4,22	23,9	0,45	0,55	neutral	0,5	disease	0,67	disease	0,59	disease	0,72	4	neutral	0,95	neutral	0,25	deleterious	1	deleterious	0,75	low_impact	-1,97	medium_impact	0,16	medium_impact	1,63	0,69	0,85	51,02	9,95	N	0,38	N	0,76	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10683	10683	G	T	MI.16147	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	214	72	A	S	Gcg/Tcg	-4,32	0	0	possibly_damaging	0,78	neutral	1	neutral	1,61	neutral	-1,52	deleterious	-2,76	low_impact	1,83	neutral	0,65	neutral	0,59	neutral	1,66	14,2	0,49	0,55	neutral	0,21	neutral	0,25	neutral	0,25	neutral	0,44	1	neutral	0,78	deleterious	0,61	neutral	-3	deleterious	0,6	low_impact	-1,31	high_impact	1,88	medium_impact	0,4	0,69	0,85	51,02	9,95	N	0,34	N	0,53	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10684	10684	C	T	MI.16148	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	215	72	A	V	gCg/gTg	1,91	0,98	0	probably_damaging	0,94	neutral	0,48	neutral	1,47	neutral	-2,65	deleterious	-3,9	medium_impact	2,7	neutral	0,74	neutral	0,5	deleterious	4,45	24,2	0,48	0,55	disease	0,63	disease	0,8	disease	0,52	disease	0,71	4	neutral	0,94	neutral	0,27	deleterious	1	deleterious	0,79	low_impact	-1,9	medium_impact	0,19	medium_impact	1,13	0,58	0,8	51,02	9,95	N	0,5	N	0,87	disease_causing	0,88	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10684	10684	C	G	MI.16149	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	215	72	A	G	gCg/gGg	1,91	0,98	0	benign	0,1	neutral	0,61	neutral	1,44	deleterious	-3,04	deleterious	-3,26	low_impact	1,31	neutral	0,8	neutral	0,9	deleterious	0,1	3,58	0,4	0,5	neutral	0,28	neutral	0,48	neutral	0,35	neutral	0,46	1	neutral	0,3	deleterious	0,76	neutral	-6	neutral	0,2	medium_impact	0,07	medium_impact	0,32	medium_impact	-0,04	0,76	0,85	51,02	9,95	N	0,44	N	0,44	disease_causing	0,86	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8447	8447	A	G	MI.1615	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	82	28	M	V	Ata/Gta	1,29	0,55	0	benign	0	neutral	1	neutral	1,29	neutral	-2,13	neutral	0,09	low_impact	1,27	neutral	1	neutral	0,97	neutral	-1,04	0,01	0,752753	0,85	neutral	0,12	neutral	0,08	disease	0,57	neutral	0,04	9	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,09	high_impact	1,98	medium_impact	-0,01	0,46	0,85	4,41	9,71	N	0,35	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10684	10684	C	A	MI.16150	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	215	72	A	E	gCg/gAg	1,91	0,98	0	probably_damaging	0,97	neutral	0,71	neutral	1,37	deleterious	-4,86	deleterious	-4,75	high_impact	3,92	neutral	0,73	neutral	0,39	deleterious	4,58	24,4	0,17	0,45	disease	0,69	disease	0,9	disease	0,69	disease	0,8	6	neutral	0,97	neutral	0,37	deleterious	2	deleterious	0,85	low_impact	-2,19	medium_impact	0,43	high_impact	2,15	0,61	0,8	51,02	9,95	N	0,54	P	0,93	disease_causing	0,93	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10686	10686	G	A	MI.16151	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	217	73	V	M	Gtg/Atg	-8,7	0	0	possibly_damaging	0,68	neutral	0,21	neutral	1,79	neutral	-2,49	neutral	-2,01	low_impact	1,92	neutral	0,8	neutral	0,71	deleterious	2,37	18,63	0,59	0,65	neutral	0,43	disease	0,51	neutral	0,32	neutral	0,49	0	neutral	0,82	neutral	0,27	neutral	-3	deleterious	0,47	low_impact	-1,1	medium_impact	-0,11	medium_impact	0,47	0,97	1	28,57	22,97	N	0,34	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	COSM488727	.	.	.	.	.	.	.	.
chrM	10686	10686	G	T	MI.16152	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	217	73	V	L	Gtg/Ttg	-8,7	0	0	possibly_damaging	0,54	neutral	1	neutral	2,08	neutral	0,43	neutral	-1,6	neutral_impact	-0,5	neutral	0,82	neutral	0,95	deleterious	1,89	15,53	0,46	0,55	neutral	0,11	disease	0,54	neutral	0,3	neutral	0,43	1	neutral	0,54	deleterious	0,73	neutral	-3	neutral	0,4	medium_impact	-0,87	high_impact	1,88	low_impact	-1,56	0,66	0,8	28,57	22,97	N	0,24	N	0,15	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10686	10686	G	C	MI.16153	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	217	73	V	L	Gtg/Ctg	-8,7	0	0	possibly_damaging	0,54	neutral	1	neutral	2,08	neutral	0,43	neutral	-1,6	neutral_impact	-0,5	neutral	0,82	neutral	0,95	neutral	1,79	14,96	0,46	0,55	neutral	0,11	disease	0,54	neutral	0,3	neutral	0,43	1	neutral	0,54	deleterious	0,73	neutral	-3	neutral	0,4	medium_impact	-0,87	high_impact	1,88	low_impact	-1,56	0,66	0,8	28,57	22,97	N	0,23	N	0,15	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10687	10687	T	C	MI.16154	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	218	73	V	A	gTg/gCg	-1,09	0	0	possibly_damaging	0,86	neutral	0,64	neutral	1,82	neutral	-1,72	deleterious	-3,68	low_impact	1,71	neutral	0,74	neutral	0,72	neutral	1,59	13,79	0,46	0,55	neutral	0,25	neutral	0,25	neutral	0,33	neutral	0,43	1	neutral	0,83	neutral	0,39	neutral	-3	deleterious	0,56	low_impact	-1,53	medium_impact	0,35	medium_impact	0,3	0,5	0,8	28,57	22,97	N	0,36	N	0,77	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10687	10687	T	G	MI.16155	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	218	73	V	G	gTg/gGg	-1,09	0	0	probably_damaging	0,98	neutral	0,44	neutral	1,76	deleterious	-4,01	deleterious	-6,64	medium_impact	3,36	neutral	0,77	neutral	0,48	deleterious	3,86	23,5	0,27	0,45	disease	0,57	disease	0,82	disease	0,6	disease	0,78	6	neutral	0,98	neutral	0,23	deleterious	1	deleterious	0,75	low_impact	-2,35	medium_impact	0,15	medium_impact	1,68	0,43	0,8	28,57	22,97	N	0,29	N	0,94	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10687	10687	T	A	MI.16156	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	218	73	V	E	gTg/gAg	-1,09	0	0	probably_damaging	0,98	neutral	0,25	neutral	1,75	deleterious	-4,26	deleterious	-5,64	medium_impact	3,36	neutral	0,79	neutral	0,35	deleterious	4,74	24,7	0,2	0,45	disease	0,57	disease	0,86	disease	0,65	disease	0,81	6	deleterious	0,98	neutral	0,14	deleterious	1	deleterious	0,8	low_impact	-2,35	medium_impact	-0,06	medium_impact	1,68	0,41	0,8	28,57	22,97	N	0,31	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10689	10689	G	C	MI.16157	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	220	74	G	R	Ggc/Cgc	-8,7	0	0	probably_damaging	1	neutral	0,35	neutral	1,54	deleterious	-8,93	deleterious	-7,96	high_impact	4,75	damaging	0,58	damaging	0,06	deleterious	3,94	23,5	0,14	0,4	disease	0,92	disease	0,96	disease	0,83	disease	0,92	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	0,06	high_impact	2,84	0,69	0,85	54,08	12,29	P	0,54	P	0,99	disease_causing	0,96	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10689	10689	G	A	MI.16158	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	220	74	G	S	Ggc/Agc	-8,7	0	0	probably_damaging	1	neutral	0,43	neutral	1,57	deleterious	-7,5	deleterious	-5,97	high_impact	4,41	damaging	0,56	damaging	0,06	deleterious	4,22	23,9	0,2	0,45	disease	0,82	disease	0,95	disease	0,72	disease	0,85	7	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	0,14	high_impact	2,56	0,81	0,85	54,08	12,29	N	0,41	N	0,97	disease_causing	0,92	0,32	rs879102108	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10689	10689	G	T	MI.16159	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	220	74	G	C	Ggc/Tgc	-8,7	0	0	probably_damaging	1	neutral	0,18	neutral	1,55	deleterious	-9,67	deleterious	-8,96	high_impact	4,21	damaging	0,55	damaging	0,03	deleterious	4,13	23,8	0,14	0,4	disease	0,94	disease	0,96	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,55	medium_impact	-0,16	high_impact	2,39	0,49	0,8	54,08	12,29	N	0,37	N	1	disease_causing	0,98	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8447	8447	A	C	MI.1616	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	82	28	M	L	Ata/Cta	1,29	0,55	0	benign	0	neutral	0,76	neutral	1,64	neutral	0,2	neutral	0,32	neutral_impact	-0,12	neutral	1	neutral	0,95	neutral	-1,57	0	0,68116519	0,85	neutral	0,15	neutral	0,06	neutral	0,48	neutral	0,03	9	neutral	0,24	deleterious	0,88	neutral	-6	neutral	0,11	high_impact	2,09	medium_impact	0,57	low_impact	-1,2	0,62	0,85	4,41	9,71	N	0,34	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10690	10690	G	T	MI.16160	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	221	74	G	V	gGc/gTc	6,06	1	0	probably_damaging	1	neutral	0,52	neutral	1,73	deleterious	-8,73	deleterious	-8,96	high_impact	4,75	damaging	0,53	damaging	0,03	deleterious	3,87	23,5	0,12	0,4	disease	0,91	disease	0,96	disease	0,75	disease	0,85	7	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0,23	high_impact	2,84	0,51	0,8	54,08	12,29	P	0,58	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10690	10690	G	C	MI.16161	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	221	74	G	A	gGc/gCc	6,06	1	0	probably_damaging	1	neutral	0,52	neutral	1,65	deleterious	-7,22	deleterious	-5,97	high_impact	3,86	neutral	0,63	damaging	0,06	deleterious	3,17	22,7	0,24	0,45	disease	0,79	disease	0,9	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-3,55	medium_impact	0,23	high_impact	2,1	0,5	0,8	54,08	12,29	P	0,58	P	0,98	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10690	10690	G	A	MI.16162	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	221	74	G	D	gGc/gAc	6,06	1	0	probably_damaging	1	neutral	0,21	neutral	1,53	deleterious	-8,38	deleterious	-6,97	high_impact	4,75	damaging	0,58	damaging	0,03	deleterious	3,84	23,4	0,08	0,35	disease	0,89	disease	0,97	disease	0,83	disease	0,92	8	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,11	high_impact	2,84	0,4	0,8	54,08	12,29	P	0,69	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10692	10692	C	G	MI.16163	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	223	75	L	V	Cta/Gta	-13,54	0	0,01	probably_damaging	1	neutral	0,4	neutral	0,36	deleterious	-5,01	deleterious	-2,99	high_impact	4,07	damaging	0,46	damaging	0,05	deleterious	3,49	23,1	0,3	0,45	neutral	0,27	disease	0,75	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,73	low_impact	-3,55	medium_impact	0,11	high_impact	2,27	0,66	0,8	54,08	12,39	N	0,32	N	0,75	disease_causing	0,62	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10692	10692	C	A	MI.16164	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	223	75	L	M	Cta/Ata	-13,54	0	0,01	probably_damaging	1	neutral	0,09	neutral	0,29	deleterious	-6,61	neutral	-1,99	high_impact	4,42	damaging	0,5	damaging	0,04	deleterious	3,8	23,4	0,25	0,45	disease	0,57	disease	0,76	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,77	low_impact	-3,55	medium_impact	-0,35	high_impact	2,57	0,63	0,8	54,08	12,39	N	0,38	N	0,77	disease_causing	0,57	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10693	10693	T	C	MI.16165	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	224	75	L	P	cTa/cCa	-0,63	0	0	probably_damaging	1	neutral	0,06	neutral	0,26	deleterious	-9,32	deleterious	-6,97	high_impact	4,42	damaging	0,4	damaging	0,02	deleterious	3,95	23,6	0,17	0,45	disease	0,89	disease	0,93	disease	0,81	disease	0,9	8	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,45	high_impact	2,57	0,4	0,8	54,08	12,39	P	0,55	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10693	10693	T	G	MI.16166	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	224	75	L	R	cTa/cGa	-0,63	0	0	probably_damaging	1	neutral	0,16	neutral	0,27	deleterious	-8,91	deleterious	-5,97	high_impact	4,76	damaging	0,45	damaging	0,02	deleterious	4,24	23,9	0,15	0,4	disease	0,86	disease	0,93	disease	0,81	disease	0,91	8	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,91	low_impact	-3,55	medium_impact	-0,19	high_impact	2,85	0,55	0,8	54,08	12,39	P	0,55	P	0,99	polymorphism	0,99	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10693	10693	T	A	MI.16167	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	224	75	L	Q	cTa/cAa	-0,63	0	0	probably_damaging	1	neutral	0,09	neutral	0,27	deleterious	-8,91	deleterious	-5,97	high_impact	4,76	damaging	0,45	damaging	0,02	deleterious	4,13	23,8	0,16	0,45	disease	0,86	disease	0,93	disease	0,74	disease	0,84	7	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,87	low_impact	-3,55	medium_impact	-0,35	high_impact	2,85	0,65	0,8	54,08	12,39	P	0,53	P	0,99	polymorphism	0,99	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10695	10695	G	C	MI.16168	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	226	76	A	P	Gcc/Ccc	-2,94	0	0	probably_damaging	0,96	neutral	0,19	neutral	1,59	deleterious	-5,23	deleterious	-4,53	high_impact	4,02	damaging	0,57	neutral	0,29	deleterious	3,83	23,4	0,18	0,45	disease	0,64	disease	0,96	disease	0,74	disease	0,89	8	neutral	0,98	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-2,07	medium_impact	-0,14	high_impact	2,23	0,65	0,8	25,51	16,97	N	0,4	N	0,91	polymorphism	0,8	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10695	10695	G	T	MI.16169	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	226	76	A	S	Gcc/Tcc	-2,94	0	0	benign	0,3	neutral	0,73	neutral	1,78	neutral	-1,6	neutral	-2,08	neutral_impact	0,02	neutral	0,8	neutral	0,92	neutral	0,89	10,01	0,53	0,6	neutral	0,12	disease	0,75	neutral	0,29	disease	0,52	0	neutral	0,22	deleterious	0,72	neutral	-6	neutral	0,28	medium_impact	-0,47	medium_impact	0,45	low_impact	-1,12	0,85	0,9	25,51	16,97	N	0,21	N	0,04	polymorphism	0,97	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8447	8447	A	T	MI.1617	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	82	28	M	L	Ata/Tta	1,29	0,55	0	benign	0	neutral	0,76	neutral	1,64	neutral	0,2	neutral	0,32	neutral_impact	-0,12	neutral	1	neutral	0,95	neutral	-1,5	0	0,68116519	0,85	neutral	0,15	neutral	0,06	neutral	0,48	neutral	0,03	9	neutral	0,24	deleterious	0,88	neutral	-6	neutral	0,11	high_impact	2,09	medium_impact	0,57	low_impact	-1,2	0,62	0,85	4,41	9,71	N	0,34	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10695	10695	G	A	MI.16170	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	226	76	A	T	Gcc/Acc	-2,94	0	0	possibly_damaging	0,86	neutral	0,39	neutral	1,75	deleterious	-3,75	deleterious	-3,38	medium_impact	2,6	neutral	0,72	neutral	0,66	deleterious	4,25	23,9	0,4	0,5	neutral	0,43	disease	0,89	disease	0,58	disease	0,71	4	neutral	0,86	neutral	0,27	NA	0	deleterious	0,74	low_impact	-1,53	medium_impact	0,1	medium_impact	1,04	0,77	0,85	25,51	16,97	N	0,41	N	0,72	polymorphism	0,93	0,1	.	.	.	.	.	head/neck tumor	.	.	.	.	.	.	.	.	.
chrM	10696	10696	C	A	MI.16171	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	227	76	A	D	gCc/gAc	1,21	0,76	0	probably_damaging	0,93	neutral	0,19	neutral	1,6	deleterious	-5,19	deleterious	-5,22	high_impact	4,02	neutral	0,64	neutral	0,31	deleterious	4,62	24,5	0,14	0,4	disease	0,66	disease	0,97	disease	0,72	disease	0,88	8	neutral	0,96	neutral	0,13	deleterious	2	deleterious	0,86	low_impact	-1,83	medium_impact	-0,14	high_impact	2,23	0,67	0,85	25,51	16,97	N	0,42	N	0,93	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10696	10696	C	T	MI.16172	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	227	76	A	V	gCc/gTc	1,21	0,76	0	possibly_damaging	0,9	neutral	0,58	neutral	1,75	deleterious	-4,59	deleterious	-3,83	medium_impact	3,47	neutral	0,72	neutral	0,54	deleterious	4,44	24,2	0,49	0,55	disease	0,57	disease	0,9	disease	0,64	disease	0,74	5	neutral	0,88	neutral	0,34	NA	0	deleterious	0,78	low_impact	-1,68	medium_impact	0,29	medium_impact	1,77	0,79	0,85	25,51	16,97	N	0,41	N	0,83	disease_causing	0,99	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10696	10696	C	G	MI.16173	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	227	76	A	G	gCc/gGc	1,21	0,76	0	possibly_damaging	0,78	neutral	0,48	neutral	1,66	deleterious	-3,3	deleterious	-3,53	medium_impact	2,41	neutral	0,69	neutral	0,62	deleterious	3,87	23,5	0,38	0,5	neutral	0,22	disease	0,9	disease	0,56	disease	0,59	2	neutral	0,77	neutral	0,35	NA	0	deleterious	0,66	low_impact	-1,31	medium_impact	0,19	medium_impact	0,88	0,81	0,85	25,51	16,97	N	0,34	N	0,5	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10698	10698	C	A	MI.16174	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	229	77	L	M	Cta/Ata	-10,78	0	0	probably_damaging	1	neutral	0,18	neutral	1,32	neutral	-2,9	neutral	-1,92	medium_impact	3,17	neutral	0,77	damaging	0,24	deleterious	2,66	20,6	0,28	0,45	neutral	0,38	disease	0,59	disease	0,53	neutral	0,46	1	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,72	low_impact	-3,55	medium_impact	-0,16	medium_impact	1,52	0,61	0,8	54,08	12,38	N	0,34	N	0,77	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10698	10698	C	G	MI.16175	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	229	77	L	V	Cta/Gta	-10,78	0	0	probably_damaging	1	neutral	0,22	neutral	1,4	neutral	-1,65	deleterious	-2,92	medium_impact	2,82	neutral	0,69	damaging	0,06	deleterious	3,49	23,1	0,26	0,45	neutral	0,41	disease	0,72	disease	0,56	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	-0,1	medium_impact	1,23	0,69	0,85	54,08	12,38	N	0,26	N	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10699	10699	T	C	MI.16176	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	230	77	L	P	cTa/cCa	-1,78	0	0	probably_damaging	1	deleterious	0,03	neutral	1,26	deleterious	-6,17	deleterious	-6,87	high_impact	4,45	damaging	0,56	damaging	0,05	deleterious	3,95	23,6	0,15	0,45	disease	0,89	disease	0,93	disease	0,72	disease	0,83	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,91	low_impact	-3,55	medium_impact	-0,63	high_impact	2,59	0,55	0,8	54,08	12,38	N	0,38	N	1	disease_causing	0,52	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10699	10699	T	G	MI.16177	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	230	77	L	R	cTa/cGa	-1,78	0	0	probably_damaging	1	neutral	0,05	neutral	1,27	deleterious	-5,74	deleterious	-5,87	high_impact	4,45	damaging	0,57	damaging	0,05	deleterious	4,25	23,9	0,1	0,4	disease	0,87	disease	0,92	disease	0,72	disease	0,83	7	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,91	low_impact	-3,55	medium_impact	-0,5	high_impact	2,59	0,38	0,8	54,08	12,38	N	0,4	N	0,99	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10699	10699	T	A	MI.16178	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	230	77	L	Q	cTa/cAa	-1,78	0	0	probably_damaging	1	deleterious	0,04	neutral	1,27	deleterious	-5,72	deleterious	-5,87	high_impact	4,45	neutral	0,68	damaging	0,06	deleterious	4,11	23,7	0,14	0,4	disease	0,86	disease	0,9	disease	0,62	disease	0,8	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,87	low_impact	-3,55	medium_impact	-0,56	high_impact	2,59	0,55	0,8	54,08	12,38	N	0,37	N	0,99	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10701	10701	C	A	MI.16179	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	232	78	L	M	Cta/Ata	-5,7	0	0	probably_damaging	1	neutral	0,19	neutral	1,62	deleterious	-3,61	neutral	-1,99	medium_impact	2,65	neutral	0,75	neutral	0,32	deleterious	2,75	21,1	0,26	0,45	neutral	0,37	neutral	0,39	neutral	0,42	neutral	0,43	1	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,71	low_impact	-3,55	medium_impact	-0,14	medium_impact	1,08	0,62	0,8	53,06	12,16	N	0,39	N	0,77	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8448	8448	T	C	MI.1618	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	83	28	M	T	aTa/aCa	-1,26	0	0,01	benign	0	neutral	0,31	neutral	1,22	deleterious	-3,78	neutral	-2,27	neutral_impact	0,7	neutral	1	neutral	0,87	neutral	-0,32	0,59	0,69564761	0,85	neutral	0,44	neutral	0,06	disease	0,64	neutral	0,04	9	neutral	0,69	deleterious	0,66	neutral	-6	neutral	0,13	high_impact	2,09	medium_impact	0,1	medium_impact	-0,5	0,38	0,85	4,41	9,71	N	0,45	N	0,28	polymorphism	1	0,04	rs879056797	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10701	10701	C	G	MI.16180	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	232	78	L	V	Cta/Gta	-5,7	0	0	probably_damaging	1	neutral	0,33	neutral	1,69	deleterious	-3,03	deleterious	-2,98	medium_impact	3,46	neutral	0,74	damaging	0,19	deleterious	3,5	23,1	0,26	0,45	neutral	0,21	disease	0,7	disease	0,52	disease	0,56	1	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,72	low_impact	-3,55	medium_impact	0,04	medium_impact	1,76	0,64	0,8	53,06	12,16	N	0,34	N	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10702	10702	T	C	MI.16181	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	233	78	L	P	cTa/cCa	-1,09	0	0	probably_damaging	1	deleterious	0,04	neutral	1,55	deleterious	-7,29	deleterious	-6,96	high_impact	4,66	damaging	0,59	damaging	0,06	deleterious	4,02	23,6	0,13	0,4	disease	0,72	disease	0,93	disease	0,76	disease	0,87	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,89	low_impact	-3,55	medium_impact	-0,56	high_impact	2,77	0,47	0,8	53,06	12,16	N	0,47	N	1	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10702	10702	T	A	MI.16182	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	233	78	L	Q	cTa/cAa	-1,09	0	0	probably_damaging	1	neutral	0,12	neutral	1,55	deleterious	-6,77	deleterious	-5,97	high_impact	4,66	neutral	0,62	damaging	0,06	deleterious	4,42	24,2	0,15	0,4	disease	0,63	disease	0,9	disease	0,67	disease	0,77	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,83	low_impact	-3,55	medium_impact	-0,27	high_impact	2,77	0,46	0,8	53,06	12,16	N	0,44	N	0,99	disease_causing	0,5	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10702	10702	T	G	MI.16183	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	233	78	L	R	cTa/cGa	-1,09	0	0	probably_damaging	1	neutral	0,17	neutral	1,55	deleterious	-6,85	deleterious	-5,97	high_impact	4,66	damaging	0,58	damaging	0,05	deleterious	4,27	23,9	0,13	0,4	disease	0,62	disease	0,92	disease	0,77	disease	0,84	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,17	high_impact	2,77	0,38	0,8	53,06	12,16	N	0,5	N	0,99	disease_causing	0,56	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10704	10704	G	A	MI.16184	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	235	79	V	I	Gtc/Atc	-0,17	0,77	0	benign	0,03	neutral	0,23	neutral	1,66	neutral	-1,88	neutral	-0,79	medium_impact	2,69	neutral	0,85	neutral	0,83	deleterious	0,66	8,56	0,54	0,6	neutral	0,44	disease	0,74	neutral	0,44	disease	0,54	1	neutral	0,76	deleterious	0,6	neutral	-3	neutral	0,23	medium_impact	0,58	medium_impact	-0,08	medium_impact	1,12	0,87	0,9	20,41	12,27	N	0,33	N	0,03	disease_causing	0,93	0,06	rs28437034	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10704	10704	G	C	MI.16185	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	235	79	V	L	Gtc/Ctc	-0,17	0,77	0	benign	0,28	neutral	0,5	neutral	1,64	neutral	-2,31	deleterious	-2,7	high_impact	4,23	neutral	0,67	neutral	0,42	neutral	1,74	14,64	0,32	0,5	disease	0,52	disease	0,92	disease	0,64	disease	0,75	5	neutral	0,4	deleterious	0,61	neutral	-2	neutral	0,35	medium_impact	-0,43	medium_impact	0,21	high_impact	2,41	0,53	0,8	20,41	12,27	N	0,36	N	0,57	disease_causing	0,98	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10704	10704	G	T	MI.16186	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	235	79	V	F	Gtc/Ttc	-0,17	0,77	0	benign	0,11	neutral	0,2	neutral	1,53	deleterious	-4,24	deleterious	-4,65	high_impact	4,58	neutral	0,69	neutral	0,44	deleterious	3,52	23,1	0,13	0,4	disease	0,75	disease	0,97	disease	0,71	disease	0,85	7	neutral	0,77	deleterious	0,55	neutral	-2	neutral	0,34	medium_impact	0,03	medium_impact	-0,12	high_impact	2,7	0,48	0,8	20,41	12,27	N	0,49	N	0,83	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10705	10705	T	C	MI.16187	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	236	79	V	A	gTc/gCc	5,13	1	0	benign	0,05	neutral	0,23	neutral	1,56	deleterious	-3,42	deleterious	-3,67	medium_impact	2,56	neutral	0,8	neutral	0,83	deleterious	0,67	8,6	0,28	0,45	neutral	0,48	disease	0,83	disease	0,62	disease	0,57	1	neutral	0,75	deleterious	0,59	neutral	-3	neutral	0,27	medium_impact	0,37	medium_impact	-0,08	medium_impact	1,01	0,33	0,8	20,41	12,27	N	0,54	P	0,23	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10705	10705	T	G	MI.16188	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	236	79	V	G	gTc/gGc	5,13	1	0	possibly_damaging	0,74	neutral	0,23	neutral	1,5	deleterious	-5,24	deleterious	-6,69	high_impact	4,58	neutral	0,68	neutral	0,47	deleterious	2,24	17,78	0,09	0,35	disease	0,66	disease	0,94	disease	0,7	disease	0,84	7	neutral	0,84	neutral	0,25	deleterious	1	deleterious	0,6	low_impact	-1,22	medium_impact	-0,08	high_impact	2,7	0,36	0,8	20,41	12,27	P	0,67	P	0,92	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10705	10705	T	A	MI.16189	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	236	79	V	D	gTc/gAc	5,13	1	0	possibly_damaging	0,89	neutral	0,05	neutral	1,49	deleterious	-5,88	deleterious	-6,66	high_impact	4,58	neutral	0,71	neutral	0,33	deleterious	4,57	24,4	0,06	0,35	disease	0,81	disease	0,97	disease	0,79	disease	0,9	8	neutral	0,98	neutral	0,08	deleterious	1	deleterious	0,75	low_impact	-1,64	medium_impact	-0,5	high_impact	2,7	0,37	0,8	20,41	12,27	P	0,68	P	0,96	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8448	8448	T	A	MI.1619	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	83	28	M	K	aTa/aAa	-1,26	0	0,01	benign	0,01	neutral	0,21	neutral	1,22	deleterious	-3,83	deleterious	-3,86	medium_impact	2,63	neutral	0,99	neutral	0,45	deleterious	2,18	17,4	0,2998577	0,85	disease	0,66	neutral	0,29	disease	0,78	neutral	0,23	5	neutral	0,79	deleterious	0,6	neutral	-3	neutral	0,26	medium_impact	1,14	medium_impact	-0,03	medium_impact	1,16	0,32	0,85	4,41	9,71	N	0,51	P	0,71	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10707	10707	T	G	MI.16190	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	238	80	S	A	Tca/Gca	-8,01	0	0	benign	0,36	neutral	0,71	neutral	2,07	neutral	0,61	neutral	-0,49	neutral_impact	0,54	neutral	0,61	neutral	0,81	neutral	0,96	10,41	0,45	0,55	neutral	0,12	neutral	0,14	neutral	0,16	neutral	0,27	5	neutral	0,27	deleterious	0,68	neutral	-6	deleterious	0,48	medium_impact	-0,57	medium_impact	0,43	medium_impact	-0,69	0,75	0,85	29,59	21,89	N	0,45	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10707	10707	T	A	MI.16191	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	238	80	S	T	Tca/Aca	-8,01	0	0	benign	0,36	neutral	0,43	neutral	1,93	neutral	-1,09	neutral	-0,36	low_impact	0,86	neutral	0,75	neutral	0,96	neutral	0,97	10,51	0,41	0,5	neutral	0,22	neutral	0,42	neutral	0,28	neutral	0,45	1	neutral	0,5	deleterious	0,54	neutral	-6	deleterious	0,6	medium_impact	-0,57	medium_impact	0,14	medium_impact	-0,42	0,84	0,9	29,59	21,89	N	0,44	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10707	10707	T	C	MI.16192	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	238	80	S	P	Tca/Cca	-8,01	0	0	probably_damaging	0,91	neutral	0,2	neutral	1,88	neutral	-2,93	neutral	-1,51	medium_impact	3,22	damaging	0,44	neutral	0,36	deleterious	4,02	23,6	0,17	0,45	neutral	0,4	disease	0,93	disease	0,68	disease	0,84	7	neutral	0,94	neutral	0,15	deleterious	1	deleterious	0,81	low_impact	-1,72	medium_impact	-0,12	medium_impact	1,56	0,74	0,85	29,59	21,89	N	0,45	N	0,66	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10708	10708	C	G	MI.16193	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	239	80	S	W	tCa/tGa	3,29	0,21	0	probably_damaging	0,95	neutral	0,17	neutral	1,86	deleterious	-5,08	neutral	-1,39	medium_impact	3,22	damaging	0,58	neutral	0,41	deleterious	4,42	24,2	0,16	0,45	disease	0,74	disease	0,89	disease	0,62	disease	0,82	6	neutral	0,97	neutral	0,11	deleterious	1	deleterious	0,83	low_impact	-1,97	medium_impact	-0,17	medium_impact	1,56	0,51	0,8	29,59	21,89	N	0,44	N	0,61	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10708	10708	C	T	MI.16194	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	239	80	S	L	tCa/tTa	3,29	0,21	0	benign	0,01	neutral	0,75	neutral	1,93	neutral	-1,01	neutral	1,14	low_impact	1,61	neutral	0,75	neutral	0,87	deleterious	3,57	23,2	0,37	0,5	neutral	0,29	disease	0,81	neutral	0,46	disease	0,69	4	neutral	0,22	deleterious	0,87	neutral	-6	neutral	0,21	medium_impact	1,03	medium_impact	0,48	medium_impact	0,21	0,84	0,9	29,59	21,89	N	0,31	N	0,47	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10710	10710	A	C	MI.16195	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	241	81	I	L	Atc/Ctc	-0,86	0	0	possibly_damaging	0,61	neutral	0,74	neutral	2,04	neutral	0,23	neutral	-1,75	neutral_impact	0,64	neutral	0,73	damaging	0,18	deleterious	2,68	20,7	0,47	0,55	neutral	0,14	disease	0,76	neutral	0,22	disease	0,61	2	neutral	0,53	deleterious	0,57	neutral	-3	deleterious	0,52	medium_impact	-0,98	medium_impact	0,46	medium_impact	-0,6	0,65	0,8	24,49	13,82	N	0,28	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10710	10710	A	G	MI.16196	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	241	81	I	V	Atc/Gtc	-0,86	0	0	benign	0,18	neutral	0,6	neutral	2,05	neutral	0,3	neutral	0,08	neutral_impact	-0,04	neutral	0,81	neutral	0,95	deleterious	0,75	9,17	0,75	0,8	neutral	0,13	neutral	0,42	neutral	0,24	neutral	0,44	1	neutral	0,28	deleterious	0,71	neutral	-6	deleterious	0,52	medium_impact	-0,2	medium_impact	0,31	low_impact	-1,17	0,47	0,8	24,49	13,82	N	0,27	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10710	10710	A	T	MI.16197	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	241	81	I	F	Atc/Ttc	-0,86	0	0	benign	0,33	neutral	0,71	neutral	1,83	neutral	-2,2	deleterious	-3,47	low_impact	1,64	neutral	0,73	damaging	0,22	neutral	1,15	11,46	0,52	0,6	neutral	0,27	disease	0,87	neutral	0,42	disease	0,77	5	neutral	0,24	deleterious	0,69	neutral	-6	neutral	0,26	medium_impact	-0,52	medium_impact	0,43	medium_impact	0,24	0,7	0,85	24,49	13,82	N	0,22	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10711	10711	T	A	MI.16198	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	242	81	I	N	aTc/aAc	0,06	0	0	probably_damaging	0,99	neutral	0,42	neutral	1,8	deleterious	-3,4	deleterious	-6,05	medium_impact	2,86	neutral	0,73	damaging	0,18	deleterious	4,72	24,6	0,45	0,55	neutral	0,37	disease	0,91	disease	0,53	disease	0,8	6	deleterious	0,99	neutral	0,22	deleterious	1	deleterious	0,79	low_impact	-2,63	medium_impact	0,13	medium_impact	1,26	0,53	0,8	24,49	13,82	N	0,27	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10711	10711	T	C	MI.16199	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	242	81	I	T	aTc/aCc	0,06	0	0	probably_damaging	0,91	neutral	0,59	neutral	1,91	neutral	-0,77	deleterious	-3,6	neutral_impact	0,32	neutral	0,75	neutral	0,93	deleterious	0,83	9,65	0,6	0,65	neutral	0,14	neutral	0,24	neutral	0,19	neutral	0,42	2	neutral	0,9	neutral	0,34	neutral	-2	deleterious	0,64	low_impact	-1,72	medium_impact	0,3	medium_impact	-0,87	0,56	0,8	24,49	13,82	N	0,35	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8602	8602	T	A	MI.162	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	76	26	F	I	Ttt/Att	-2,65	0	0,01	benign	0,06	neutral	0,38	neutral	4,35	neutral	-0,36	neutral	-2,41	neutral_impact	0,15	neutral	0,83	neutral	0,72	neutral	1,08	11,09	0,29	0,65	neutral	0,42	neutral	0,32	neutral	0,3	neutral	0,47	1	neutral	0,58	deleterious	0,66	neutral	-6	neutral	0,18	medium_impact	0,38	medium_impact	0,17	medium_impact	-0,97	0,44	0,9	15,49	8,03	N	0,32	N	0,94	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8449	8449	A	T	MI.1620	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	84	28	M	I	atA/atT	2,9	0,49	0	benign	0	neutral	0,77	neutral	1,36	neutral	-1,3	neutral	0,52	neutral_impact	-0,09	neutral	0,98	neutral	0,97	neutral	-0,71	0,07	0,69199839	0,85	neutral	0,11	neutral	0,06	neutral	0,47	neutral	0,03	9	neutral	0,23	deleterious	0,89	neutral	-6	neutral	0,12	high_impact	2,09	medium_impact	0,59	low_impact	-1,18	0,57	0,85	4,41	9,71	N	0,4	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10711	10711	T	G	MI.16200	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	242	81	I	S	aTc/aGc	0,06	0	0	probably_damaging	0,96	neutral	0,64	neutral	1,86	neutral	-1,41	deleterious	-5,05	low_impact	1,68	neutral	0,73	neutral	0,52	deleterious	2,69	20,7	0,43	0,55	neutral	0,17	disease	0,78	neutral	0,31	disease	0,56	1	neutral	0,95	neutral	0,34	neutral	-2	deleterious	0,7	low_impact	-2,07	medium_impact	0,35	medium_impact	0,27	0,58	0,8	24,49	13,82	N	0,24	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10712	10712	C	G	MI.16201	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	243	81	I	M	atC/atG	4,21	0,27	0	probably_damaging	0,98	neutral	0,28	neutral	1,87	neutral	-1,3	neutral	-2,01	low_impact	0,94	neutral	0,79	neutral	0,77	deleterious	2,34	18,46	0,62	0,65	neutral	0,11	disease	0,67	neutral	0,18	neutral	0,46	1	deleterious	0,98	neutral	0,15	neutral	-2	deleterious	0,66	low_impact	-2,35	medium_impact	-0,02	medium_impact	-0,35	0,74	0,85	24,49	13,82	N	0,4	N	0,73	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10712	10712	C	A	MI.16202	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	243	81	I	M	atC/atA	4,21	0,27	0	probably_damaging	0,98	neutral	0,28	neutral	1,87	neutral	-1,3	neutral	-2,01	low_impact	0,94	neutral	0,79	neutral	0,77	deleterious	2,75	21,1	0,62	0,65	neutral	0,11	disease	0,67	neutral	0,18	neutral	0,46	1	deleterious	0,98	neutral	0,15	neutral	-2	deleterious	0,66	low_impact	-2,35	medium_impact	-0,02	medium_impact	-0,35	0,74	0,85	24,49	13,82	N	0,41	N	0,73	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10713	10713	T	A	MI.16203	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	244	82	S	T	Tcc/Acc	-13,08	0	0	probably_damaging	0,92	neutral	0,41	neutral	1,88	neutral	-1,52	deleterious	-2,88	medium_impact	2,05	neutral	0,73	damaging	0,27	deleterious	2,23	17,73	0,5	0,6	neutral	0,28	neutral	0,35	neutral	0,23	neutral	0,46	1	neutral	0,92	neutral	0,25	deleterious	1	deleterious	0,64	low_impact	-1,78	medium_impact	0,12	medium_impact	0,58	0,87	0,9	55,1	11,36	N	0,34	N	0,61	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10713	10713	T	C	MI.16204	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	244	82	S	P	Tcc/Ccc	-13,08	0	0	benign	0,29	neutral	0,2	neutral	1,83	deleterious	-3,68	deleterious	-4,85	high_impact	4,04	neutral	0,64	damaging	0,1	deleterious	2,28	18,03	0,24	0,45	disease	0,53	disease	0,95	disease	0,64	disease	0,84	7	neutral	0,76	neutral	0,46	neutral	-2	neutral	0,36	medium_impact	-0,45	medium_impact	-0,12	high_impact	2,25	0,75	0,85	55,1	11,36	N	0,33	N	0,85	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10713	10713	T	G	MI.16205	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	244	82	S	A	Tcc/Gcc	-13,08	0	0	possibly_damaging	0,78	neutral	0,52	neutral	1,94	neutral	-0,61	deleterious	-2,88	medium_impact	1,94	neutral	0,74	neutral	0,43	deleterious	2,1	16,87	0,63	0,65	neutral	0,14	neutral	0,36	neutral	0,3	neutral	0,45	1	neutral	0,76	neutral	0,37	NA	0	deleterious	0,58	low_impact	-1,31	medium_impact	0,23	medium_impact	0,49	0,81	0,85	55,1	11,36	N	0,35	N	0,37	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10714	10714	C	G	MI.16206	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	245	82	S	C	tCc/tGc	1,21	0,8	0	probably_damaging	0,99	neutral	0,17	neutral	1,82	deleterious	-3,95	deleterious	-4,81	high_impact	4,04	neutral	0,7	damaging	0,07	deleterious	3,68	23,3	0,31	0,45	disease	0,55	disease	0,87	disease	0,51	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,78	low_impact	-2,63	medium_impact	-0,17	high_impact	2,25	0,7	0,85	55,1	11,36	N	0,38	N	0,81	polymorphism	0,6	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10714	10714	C	A	MI.16207	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	245	82	S	Y	tCc/tAc	1,21	0,8	0	probably_damaging	0,99	neutral	1	neutral	2,07	neutral	0,5	deleterious	-5,53	medium_impact	2,22	neutral	0,77	damaging	0,13	deleterious	4,19	23,8	0,36	0,5	neutral	0,24	disease	0,9	neutral	0,42	disease	0,73	5	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,75	low_impact	-2,63	high_impact	1,88	medium_impact	0,72	0,76	0,85	55,1	11,36	N	0,2	N	0,59	disease_causing	0,54	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10714	10714	C	T	MI.16208	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	245	82	S	F	tCc/tTc	1,21	0,8	0	probably_damaging	0,99	neutral	0,7	neutral	1,9	neutral	-1,1	deleterious	-5,55	medium_impact	2,94	neutral	0,75	damaging	0,08	deleterious	4,35	24,1	0,44	0,55	neutral	0,36	disease	0,91	disease	0,53	disease	0,78	6	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,78	low_impact	-2,63	medium_impact	0,41	medium_impact	1,33	0,54	0,8	55,1	11,36	N	0,25	N	0,89	disease_causing	0,67	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10716	10716	A	T	MI.16209	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	247	83	N	Y	Aac/Tac	-11,7	0	0	probably_damaging	0,92	neutral	1	neutral	1,92	neutral	-2,94	deleterious	-7,01	medium_impact	2,72	neutral	0,75	neutral	0,35	deleterious	3,75	23,3	0,54	0,6	disease	0,62	disease	0,87	disease	0,63	disease	0,79	6	neutral	0,92	deleterious	0,54	deleterious	1	deleterious	0,81	low_impact	-1,78	high_impact	1,88	medium_impact	1,14	0,5	0,8	52,04	9,32	N	0,21	N	0,92	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8449	8449	A	C	MI.1621	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	84	28	M	I	atA/atC	2,9	0,49	0	benign	0	neutral	0,77	neutral	1,36	neutral	-1,3	neutral	0,52	neutral_impact	-0,09	neutral	0,98	neutral	0,97	neutral	-0,77	0,05	0,69199839	0,85	neutral	0,11	neutral	0,06	neutral	0,47	neutral	0,03	9	neutral	0,23	deleterious	0,89	neutral	-6	neutral	0,12	high_impact	2,09	medium_impact	0,59	low_impact	-1,18	0,57	0,85	4,41	9,71	N	0,4	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10716	10716	A	C	MI.16210	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	247	83	N	H	Aac/Cac	-11,7	0	0	probably_damaging	0,94	neutral	0,55	neutral	1,94	neutral	-1,81	deleterious	-4,38	medium_impact	2,44	neutral	0,85	neutral	0,44	deleterious	3,05	22,4	0,66	0,7	neutral	0,5	disease	0,78	disease	0,55	disease	0,7	4	neutral	0,93	neutral	0,31	deleterious	1	deleterious	0,77	low_impact	-1,9	medium_impact	0,26	medium_impact	0,91	0,48	0,8	52,04	9,32	N	0,22	N	0,58	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10716	10716	A	G	MI.16211	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	247	83	N	D	Aac/Gac	-11,7	0	0	benign	0,05	neutral	0,24	neutral	1,96	neutral	-1,45	deleterious	-4,07	medium_impact	3,42	neutral	0,84	neutral	0,49	deleterious	1,96	15,99	0,8	0,85	neutral	0,37	disease	0,84	disease	0,62	disease	0,78	6	neutral	0,74	deleterious	0,6	neutral	-3	deleterious	0,62	medium_impact	0,37	medium_impact	-0,07	medium_impact	1,73	0,71	0,85	52,04	9,32	N	0,38	N	0,87	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10717	10717	A	G	MI.16212	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	248	83	N	S	aAc/aGc	3,06	0,91	0	benign	0,08	neutral	0,53	neutral	2,01	neutral	-1,04	deleterious	-3,9	medium_impact	2,26	neutral	0,88	neutral	0,81	deleterious	0,18	4,47	0,74	0,75	neutral	0,31	disease	0,72	neutral	0,5	disease	0,58	2	neutral	0,4	deleterious	0,73	neutral	-3	neutral	0,24	medium_impact	0,17	medium_impact	0,24	medium_impact	0,76	0,37	0,8	52,04	9,32	N	0,33	N	0,8	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10717	10717	A	C	MI.16213	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	248	83	N	T	aAc/aCc	3,06	0,91	0	possibly_damaging	0,52	neutral	0,41	neutral	1,97	neutral	-1,21	deleterious	-4,94	low_impact	1,64	neutral	0,87	neutral	0,83	neutral	1,79	14,92	0,7	0,75	neutral	0,21	disease	0,73	neutral	0,49	disease	0,59	2	neutral	0,59	neutral	0,45	neutral	-3	deleterious	0,52	medium_impact	-0,84	medium_impact	0,12	medium_impact	0,24	0,51	0,8	52,04	9,32	N	0,39	N	0,75	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10717	10717	A	T	MI.16214	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	248	83	N	I	aAc/aTc	3,06	0,91	0	benign	0,11	neutral	0,45	neutral	1,92	neutral	-2,55	deleterious	-7,88	medium_impact	3,42	neutral	0,78	neutral	0,57	deleterious	2,25	17,83	0,53	0,6	disease	0,55	disease	0,88	disease	0,57	disease	0,79	6	neutral	0,48	deleterious	0,67	neutral	-3	neutral	0,32	medium_impact	0,03	medium_impact	0,16	medium_impact	1,73	0,41	0,8	52,04	9,32	N	0,41	N	0,94	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10718	10718	C	G	MI.16215	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	249	83	N	K	aaC/aaG	2,6	0,91	0	benign	0,12	neutral	0,29	neutral	2,05	neutral	0,46	deleterious	-4,92	medium_impact	2,02	neutral	0,78	neutral	0,45	neutral	1,05	10,94	0,85	0,85	neutral	0,21	disease	0,85	disease	0,54	disease	0,75	5	neutral	0,67	deleterious	0,59	neutral	-3	neutral	0,25	medium_impact	-0,01	medium_impact	-0,01	medium_impact	0,56	0,57	0,8	52,04	9,32	N	0,34	N	0,84	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10718	10718	C	A	MI.16216	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	249	83	N	K	aaC/aaA	2,6	0,91	0	benign	0,12	neutral	0,29	neutral	2,05	neutral	0,46	deleterious	-4,92	medium_impact	2,02	neutral	0,78	neutral	0,45	neutral	1,49	13,28	0,85	0,85	neutral	0,21	disease	0,85	disease	0,54	disease	0,75	5	neutral	0,67	deleterious	0,59	neutral	-3	neutral	0,25	medium_impact	-0,01	medium_impact	-0,01	medium_impact	0,56	0,57	0,8	52,04	9,32	N	0,34	N	0,84	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10719	10719	A	C	MI.16217	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	250	84	T	P	Aca/Cca	-6,16	0	0	probably_damaging	0,94	neutral	0,2	neutral	1,81	deleterious	-3,5	deleterious	-4,66	high_impact	4,17	neutral	0,61	neutral	0,3	deleterious	3,44	23	0,27	0,45	disease	0,74	disease	0,95	disease	0,79	disease	0,91	8	neutral	0,96	neutral	0,13	deleterious	2	deleterious	0,84	low_impact	-1,9	medium_impact	-0,12	high_impact	2,36	0,59	0,8	24,49	9,28	N	0,46	N	0,96	polymorphism	0,92	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10719	10719	A	T	MI.16218	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	250	84	T	S	Aca/Tca	-6,16	0	0	possibly_damaging	0,68	neutral	0,43	neutral	1,92	neutral	-0,77	neutral	-2,43	low_impact	0,93	neutral	0,81	neutral	0,92	deleterious	0,58	7,99	0,67	0,7	neutral	0,27	disease	0,83	neutral	0,46	disease	0,58	2	neutral	0,69	neutral	0,38	neutral	-3	deleterious	0,57	low_impact	-1,1	medium_impact	0,14	medium_impact	-0,36	0,68	0,85	24,49	9,28	N	0,27	N	0,85	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10719	10719	A	G	MI.16219	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	250	84	T	A	Aca/Gca	-6,16	0	0	benign	0,4	neutral	0,49	neutral	1,86	neutral	-1,6	deleterious	-3,56	medium_impact	2,33	neutral	0,77	neutral	0,62	neutral	1,79	14,9	0,79	0,8	neutral	0,42	disease	0,83	disease	0,65	disease	0,6	2	neutral	0,45	deleterious	0,55	neutral	-3	neutral	0,43	medium_impact	-0,64	medium_impact	0,2	medium_impact	0,82	0,68	0,85	24,49	9,28	N	0,27	N	0,91	polymorphism	0,98	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8450	8450	T	A	MI.1622	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	85	29	L	M	Tta/Ata	-13,06	0	0,01	probably_damaging	0,98	neutral	0,22	neutral	-0,16	deleterious	-6,09	neutral	-0,58	medium_impact	2,4	neutral	1	neutral	0,57	deleterious	2,21	17,57	0,46643282	0,85	disease	0,51	neutral	0,26	neutral	0,27	neutral	0,24	5	deleterious	0,98	neutral	0,12	deleterious	1	deleterious	0,73	low_impact	-2,36	medium_impact	-0,02	medium_impact	0,96	0,73	0,85	5,88	10,73	N	0,53	P	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10720	10720	C	A	MI.16220	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	251	84	T	K	aCa/aAa	4,44	0,97	0	possibly_damaging	0,81	neutral	0,3	neutral	1,92	neutral	-0,71	deleterious	-4,36	medium_impact	2,98	neutral	0,72	neutral	0,51	deleterious	2,72	20,9	0,42	0,55	disease	0,71	disease	0,95	disease	0,72	disease	0,84	7	neutral	0,85	neutral	0,25	NA	0	deleterious	0,78	low_impact	-1,38	medium_impact	0,01	medium_impact	1,36	0,75	0,85	24,49	9,28	P	0,55	P	0,95	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10720	10720	C	T	MI.16221	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	251	84	T	M	aCa/aTa	4,44	0,97	0	benign	0,2	neutral	0,24	neutral	1,81	deleterious	-3,36	deleterious	-3,96	medium_impact	2,65	neutral	0,8	neutral	0,65	deleterious	2,29	18,1	0,53	0,6	disease	0,84	disease	0,91	disease	0,67	disease	0,77	5	neutral	0,72	deleterious	0,52	neutral	-3	neutral	0,34	medium_impact	-0,25	medium_impact	-0,07	medium_impact	1,08	0,73	0,85	24,49	9,28	N	0,44	N	0,99	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10722	10722	T	C	MI.16222	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	253	85	Y	H	Tat/Cat	-13,54	0	0	benign	0,4	neutral	0,93	neutral	1,93	neutral	-0,45	deleterious	-4,22	neutral_impact	0,46	neutral	0,72	neutral	0,78	neutral	-0,79	0,05	0,68	0,7	neutral	0,11	neutral	0,26	neutral	0,37	neutral	0,39	2	neutral	0,33	deleterious	0,77	neutral	-6	neutral	0,21	medium_impact	-0,64	medium_impact	0,83	medium_impact	-0,75	0,3	0,8	58,16	10,58	N	0,3	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10722	10722	T	A	MI.16223	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	253	85	Y	N	Tat/Aat	-13,54	0	0	probably_damaging	0,96	neutral	0,44	neutral	1,81	neutral	-1,92	deleterious	-8,37	medium_impact	2,62	neutral	0,7	neutral	0,63	deleterious	4,17	23,8	0,49	0,55	disease	0,59	disease	0,92	disease	0,6	disease	0,76	5	neutral	0,96	neutral	0,24	deleterious	1	deleterious	0,82	low_impact	-2,07	medium_impact	0,15	medium_impact	1,06	0,23	0,8	58,16	10,58	N	0,36	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10722	10722	T	G	MI.16224	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	253	85	Y	D	Tat/Gat	-13,54	0	0	probably_damaging	0,98	neutral	0,23	neutral	1,78	neutral	-2,82	deleterious	-9,41	high_impact	3,82	neutral	0,6	neutral	0,37	deleterious	4,12	23,8	0,5	0,6	disease	0,67	disease	0,94	disease	0,67	disease	0,85	7	deleterious	0,98	neutral	0,13	deleterious	2	deleterious	0,86	low_impact	-2,35	medium_impact	-0,08	high_impact	2,06	0,31	0,8	58,16	10,58	N	0,42	N	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10723	10723	A	C	MI.16225	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	254	85	Y	S	tAt/tCt	2,14	0,98	0	probably_damaging	0,97	neutral	0,41	neutral	1,8	neutral	-2,19	deleterious	-8,48	medium_impact	2,29	neutral	0,68	neutral	0,49	deleterious	3,75	23,3	0,41	0,5	neutral	0,49	disease	0,9	disease	0,62	disease	0,78	6	neutral	0,97	neutral	0,22	deleterious	1	deleterious	0,8	low_impact	-2,19	medium_impact	0,12	medium_impact	0,78	0,3	0,8	58,16	10,58	N	0,5	N	0,98	disease_causing	0,92	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10723	10723	A	T	MI.16226	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	254	85	Y	F	tAt/tTt	2,14	0,98	0	probably_damaging	0,95	neutral	0,67	neutral	1,79	neutral	-2,48	deleterious	-3,79	medium_impact	2,05	neutral	0,7	neutral	0,47	deleterious	3,34	22,9	0,49	0,55	neutral	0,29	disease	0,88	disease	0,62	disease	0,78	6	neutral	0,94	neutral	0,36	deleterious	1	deleterious	0,75	low_impact	-1,97	medium_impact	0,38	medium_impact	0,58	0,35	0,8	58,16	10,58	N	0,44	N	0,92	polymorphism	0,53	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10723	10723	A	G	MI.16227	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	254	85	Y	C	tAt/tGt	2,14	0,98	0	probably_damaging	0,99	neutral	0,17	neutral	1,75	deleterious	-4,15	deleterious	-8,62	medium_impact	2,92	neutral	0,61	neutral	0,35	deleterious	3,5	23,1	0,54	0,6	neutral	0,25	disease	0,93	disease	0,68	disease	0,8	6	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,78	low_impact	-2,63	medium_impact	-0,17	medium_impact	1,31	0,11	0,8	58,16	10,58	N	0,5	N	0,99	disease_causing	0,95	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10725	10725	G	C	MI.16228	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	256	86	G	R	Ggc/Cgc	-5,24	0	0	probably_damaging	0,99	neutral	0,41	neutral	1,49	deleterious	-3,12	deleterious	-7,74	high_impact	4,14	neutral	0,68	damaging	0,15	deleterious	4,11	23,7	0,32	0,5	disease	0,92	disease	0,96	disease	0,73	disease	0,85	7	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,91	low_impact	-2,63	medium_impact	0,12	high_impact	2,33	0,76	0,85	55,1	12,5	N	0,37	N	0,99	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10725	10725	G	T	MI.16229	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	256	86	G	C	Ggc/Tgc	-5,24	0	0	probably_damaging	1	neutral	0,17	neutral	1,42	deleterious	-6,4	deleterious	-8,56	high_impact	4,7	neutral	0,7	damaging	0,18	deleterious	4,26	23,9	0,26	0,45	disease	0,94	disease	0,96	disease	0,67	disease	0,83	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	-0,17	high_impact	2,8	0,58	0,8	55,1	12,5	N	0,52	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8450	8450	T	G	MI.1623	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	85	29	L	V	Tta/Gta	-13,06	0	0,01	possibly_damaging	0,87	neutral	0,5	neutral	-0,12	deleterious	-5,16	neutral	-1,51	medium_impact	2,96	neutral	0,98	damaging	0,23	deleterious	1,98	16,09	0,54903459	0,85	neutral	0,32	neutral	0,23	neutral	0,39	neutral	0,15	7	neutral	0,86	neutral	0,32	NA	0	deleterious	0,68	low_impact	-1,54	medium_impact	0,29	medium_impact	1,44	0,44	0,85	5,88	10,73	N	0,41	N	0,37	polymorphism	1	0,04	rs28461343	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10725	10725	G	A	MI.16230	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	256	86	G	S	Ggc/Agc	-5,24	0	0	probably_damaging	0,97	neutral	0,47	neutral	1,52	neutral	-2,62	deleterious	-5,79	medium_impact	3,31	neutral	0,74	neutral	0,38	deleterious	4,37	24,1	0,35	0,5	disease	0,82	disease	0,91	disease	0,56	disease	0,61	2	neutral	0,97	neutral	0,25	deleterious	1	deleterious	0,88	low_impact	-2,19	medium_impact	0,18	medium_impact	1,64	0,72	0,85	55,1	12,5	N	0,35	N	0,97	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10726	10726	G	A	MI.16231	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	257	86	G	D	gGc/gAc	2,37	0,99	0	probably_damaging	0,98	neutral	0,31	neutral	1,48	deleterious	-3,42	deleterious	-6,79	high_impact	4,34	neutral	0,7	damaging	0,19	deleterious	3,93	23,5	0,28	0,45	disease	0,89	disease	0,96	disease	0,7	disease	0,84	7	deleterious	0,98	neutral	0,17	deleterious	2	deleterious	0,9	low_impact	-2,35	medium_impact	0,02	high_impact	2,5	0,37	0,8	55,1	12,5	P	0,56	P	0,99	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10726	10726	G	T	MI.16232	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	257	86	G	V	gGc/gTc	2,37	0,99	0	probably_damaging	0,99	neutral	0,52	neutral	1,44	deleterious	-4,7	deleterious	-8,68	high_impact	4,7	neutral	0,67	damaging	0,23	deleterious	3,9	23,5	0,27	0,45	disease	0,91	disease	0,95	disease	0,66	disease	0,83	6	deleterious	0,99	neutral	0,27	deleterious	2	deleterious	0,91	low_impact	-2,63	medium_impact	0,23	high_impact	2,8	0,44	0,8	55,1	12,5	P	0,65	P	1	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10726	10726	G	C	MI.16233	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	257	86	G	A	gGc/gCc	2,37	0,99	0	probably_damaging	0,97	neutral	0,53	neutral	1,48	deleterious	-3,28	deleterious	-5,78	high_impact	3,72	neutral	0,77	neutral	0,48	deleterious	3,16	22,6	0,48	0,55	disease	0,79	disease	0,87	neutral	0,46	disease	0,61	2	neutral	0,96	neutral	0,28	deleterious	2	deleterious	0,87	low_impact	-2,19	medium_impact	0,24	medium_impact	1,98	0,81	0,85	55,1	12,5	N	0,46	N	0,98	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10728	10728	C	G	MI.16234	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	259	87	L	V	Cta/Gta	-20	0	0,01	probably_damaging	0,98	neutral	0,52	neutral	1,98	neutral	-0,69	neutral	-1,18	neutral_impact	0,41	neutral	0,83	neutral	0,79	deleterious	2,15	17,19	0,71	0,75	neutral	0,17	neutral	0,39	neutral	0,5	neutral	0,45	1	neutral	0,97	neutral	0,27	neutral	-2	deleterious	0,64	low_impact	-2,35	medium_impact	0,23	medium_impact	-0,79	0,74	0,85	32,65	17,69	N	0,29	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10728	10728	C	A	MI.16235	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	259	87	L	M	Cta/Ata	-20	0	0,01	probably_damaging	1	neutral	0,27	neutral	1,96	neutral	-1,74	neutral	-0,69	low_impact	1,45	neutral	0,81	neutral	0,85	deleterious	3,44	23	0,49	0,55	neutral	0,32	neutral	0,32	neutral	0,32	neutral	0,47	1	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,66	low_impact	-3,55	medium_impact	-0,03	medium_impact	0,08	0,71	0,85	32,65	17,69	N	0,4	N	0,51	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10729	10729	T	C	MI.16236	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	260	87	L	P	cTa/cCa	-0,4	0	0	probably_damaging	1	neutral	0,19	neutral	1,97	neutral	-1,24	deleterious	-3,74	low_impact	1,64	neutral	0,64	neutral	0,32	deleterious	3,99	23,6	0,43	0,55	neutral	0,3	disease	0,88	disease	0,52	disease	0,79	6	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,77	low_impact	-3,55	medium_impact	-0,14	medium_impact	0,24	0,52	0,8	32,65	17,69	N	0,34	N	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10729	10729	T	G	MI.16237	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	260	87	L	R	cTa/cGa	-0,4	0	0	benign	0,38	neutral	0,35	neutral	2	neutral	-0,02	deleterious	-2,84	medium_impact	2	neutral	0,82	damaging	0,24	neutral	1,42	12,9	0,45	0,55	neutral	0,16	disease	0,84	disease	0,59	disease	0,81	6	neutral	0,59	deleterious	0,49	neutral	-3	neutral	0,38	medium_impact	-0,61	medium_impact	0,06	medium_impact	0,54	0,68	0,85	32,65	17,69	N	0,26	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10729	10729	T	A	MI.16238	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	260	87	L	Q	cTa/cAa	-0,4	0	0	probably_damaging	0,98	neutral	0,28	neutral	2,01	neutral	0,29	deleterious	-2,85	low_impact	1,64	neutral	0,69	damaging	0,19	deleterious	4,14	23,8	0,46	0,55	neutral	0,14	disease	0,66	disease	0,51	disease	0,6	2	deleterious	0,98	neutral	0,15	neutral	-2	deleterious	0,67	low_impact	-2,35	medium_impact	-0,02	medium_impact	0,24	0,74	0,85	32,65	17,69	N	0,29	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10731	10731	G	A	MI.16239	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	262	88	D	N	Gac/Aac	-7,55	0	0	benign	0,29	neutral	0,52	neutral	1,66	deleterious	-3,48	deleterious	-4,8	high_impact	3,88	neutral	0,73	neutral	0,5	deleterious	2,41	18,9	0,77	0,8	disease	0,59	disease	0,93	disease	0,71	disease	0,79	6	neutral	0,38	deleterious	0,62	neutral	-2	neutral	0,37	medium_impact	-0,45	medium_impact	0,23	high_impact	2,11	0,77	0,85	53,06	12,24	N	0,33	N	0,96	disease_causing	0,67	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8451	8451	T	C	MI.1624	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	86	29	L	S	tTa/tCa	0,13	0	0	probably_damaging	0,95	neutral	0,41	neutral	-0,21	deleterious	-9,55	neutral	-0,36	low_impact	1,11	neutral	0,96	neutral	0,88	deleterious	2,09	16,81	0,24813243	0,85	neutral	0,09	neutral	0,21	neutral	0,34	neutral	0,11	8	neutral	0,95	neutral	0,23	neutral	-2	deleterious	0,68	low_impact	-1,97	medium_impact	0,2	medium_impact	-0,15	0,57	0,85	5,88	10,73	N	0,45	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10731	10731	G	C	MI.16240	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	262	88	D	H	Gac/Cac	-7,55	0	0	probably_damaging	0,95	neutral	0,55	neutral	1,64	deleterious	-4,48	deleterious	-6,72	high_impact	4,13	neutral	0,71	damaging	0,21	deleterious	3,69	23,3	0,45	0,55	disease	0,81	disease	0,95	disease	0,78	disease	0,9	8	neutral	0,95	neutral	0,3	deleterious	2	deleterious	0,87	low_impact	-1,97	medium_impact	0,26	high_impact	2,32	0,54	0,8	53,06	12,24	N	0,37	N	0,97	disease_causing	0,91	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10731	10731	G	T	MI.16241	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	262	88	D	Y	Gac/Tac	-7,55	0	0	benign	0,29	neutral	0,91	neutral	1,65	deleterious	-4,28	deleterious	-8,64	high_impact	4,68	neutral	0,73	damaging	0,25	deleterious	2,17	17,34	0,27	0,45	disease	0,89	disease	0,98	disease	0,78	disease	0,89	8	neutral	0,19	deleterious	0,81	neutral	-2	neutral	0,43	medium_impact	-0,45	medium_impact	0,77	high_impact	2,78	0,22	0,8	53,06	12,24	N	0,51	P	0,98	disease_causing	0,96	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10732	10732	A	C	MI.16242	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	263	88	D	A	gAc/gCc	4,21	1	0	possibly_damaging	0,86	neutral	0,67	neutral	1,71	neutral	-2,3	deleterious	-7,65	high_impact	4,13	neutral	0,73	neutral	0,49	deleterious	3,52	23,1	0,38	0,5	disease	0,54	disease	0,94	disease	0,73	disease	0,84	7	neutral	0,84	neutral	0,41	deleterious	1	deleterious	0,78	low_impact	-1,53	medium_impact	0,38	high_impact	2,32	0,51	0,8	53,06	12,24	P	0,58	P	0,97	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10732	10732	A	G	MI.16243	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	263	88	D	G	gAc/gGc	4,21	1	0	possibly_damaging	0,86	neutral	0,49	neutral	1,65	deleterious	-3,84	deleterious	-6,72	high_impact	4,13	neutral	0,7	neutral	0,38	deleterious	3,76	23,3	0,44	0,55	disease	0,68	disease	0,95	disease	0,74	disease	0,88	8	neutral	0,85	neutral	0,32	deleterious	1	deleterious	0,73	low_impact	-1,53	medium_impact	0,2	high_impact	2,32	0,32	0,8	53,06	12,24	P	0,63	P	0,94	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10732	10732	A	T	MI.16244	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	263	88	D	V	gAc/gTc	4,21	1	0	probably_damaging	0,93	neutral	0,5	neutral	1,83	neutral	-0,93	deleterious	-8,64	high_impact	3,99	neutral	0,68	neutral	0,29	deleterious	3,66	23,2	0,24	0,45	disease	0,82	disease	0,97	disease	0,76	disease	0,89	8	neutral	0,93	neutral	0,29	deleterious	2	deleterious	0,85	low_impact	-1,83	medium_impact	0,21	high_impact	2,21	0,27	0,8	53,06	12,24	P	0,6	P	0,98	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10733	10733	C	G	MI.16245	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	264	88	D	E	gaC/gaG	5,6	1	0	possibly_damaging	0,78	neutral	0,49	neutral	1,7	neutral	-2,42	deleterious	-3,84	high_impact	3,58	neutral	0,77	neutral	0,37	deleterious	3,79	23,4	0,68	0,7	neutral	0,47	disease	0,94	disease	0,68	disease	0,82	6	neutral	0,76	neutral	0,36	deleterious	1	deleterious	0,75	low_impact	-1,31	medium_impact	0,2	medium_impact	1,86	0,54	0,8	53,06	12,24	P	0,61	P	0,93	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10733	10733	C	A	MI.16246	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	264	88	D	E	gaC/gaA	5,6	1	0	possibly_damaging	0,78	neutral	0,49	neutral	1,7	neutral	-2,42	deleterious	-3,84	high_impact	3,58	neutral	0,77	neutral	0,37	deleterious	3,99	23,6	0,68	0,7	neutral	0,47	disease	0,94	disease	0,68	disease	0,82	6	neutral	0,76	neutral	0,36	deleterious	1	deleterious	0,75	low_impact	-1,31	medium_impact	0,2	medium_impact	1,86	0,54	0,8	53,06	12,24	P	0,59	P	0,93	disease_causing	1	0,2	rs28709356	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10734	10734	T	C	MI.16247	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	265	89	Y	H	Tac/Cac	-3,4	0	0	benign	0,01	neutral	0,56	neutral	2	neutral	-0,01	deleterious	-2,88	low_impact	1,11	neutral	0,83	neutral	0,91	neutral	-0,78	0,05	0,68	0,7	neutral	0,23	neutral	0,22	neutral	0,31	neutral	0,35	3	neutral	0,42	deleterious	0,78	neutral	-6	neutral	0,16	medium_impact	1,03	medium_impact	0,27	medium_impact	-0,21	0,3	0,8	37,76	8,67	N	0,37	N	1	polymorphism	0,66	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10734	10734	T	A	MI.16248	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	265	89	Y	N	Tac/Aac	-3,4	0	0	possibly_damaging	0,53	neutral	0,34	neutral	2,04	neutral	0,52	deleterious	-7,18	medium_impact	2,3	neutral	0,77	neutral	0,78	neutral	1,65	14,12	0,48	0,55	disease	0,57	disease	0,73	neutral	0,46	disease	0,61	2	neutral	0,65	neutral	0,41	NA	0	deleterious	0,52	medium_impact	-0,85	medium_impact	0,05	medium_impact	0,79	0,29	0,8	37,76	8,67	N	0,32	N	0,99	disease_causing	0,85	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10734	10734	T	G	MI.16249	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	265	89	Y	D	Tac/Gac	-3,4	0	0	possibly_damaging	0,72	neutral	0,23	neutral	2,2	neutral	1,79	deleterious	-8,3	medium_impact	3,42	neutral	0,78	neutral	0,3	deleterious	3,82	23,4	0,47	0,55	disease	0,59	disease	0,85	disease	0,67	disease	0,8	6	neutral	0,83	neutral	0,26	NA	0	deleterious	0,72	low_impact	-1,18	medium_impact	-0,08	medium_impact	1,73	0,32	0,8	37,76	8,67	N	0,35	N	1	disease_causing	0,81	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8451	8451	T	G	MI.1625	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	86	29	L	W	tTa/tGa	0,13	0	0	probably_damaging	0,98	neutral	0,18	neutral	-0,21	deleterious	-9,47	deleterious	-3,39	high_impact	3,5	neutral	0,98	damaging	0,15	deleterious	3,61	23,2	0,20000037	0,85	disease	0,8	neutral	0,4	neutral	0,49	neutral	0,23	5	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,79	low_impact	-2,36	medium_impact	-0,08	medium_impact	1,9	0,63	0,85	5,88	10,73	N	0,51	P	0,67	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10735	10735	A	T	MI.16250	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	266	89	Y	F	tAc/tTc	0,75	0,09	0	possibly_damaging	0,56	neutral	0,7	neutral	1,95	neutral	-1,41	deleterious	-3,58	medium_impact	2,02	neutral	0,8	neutral	0,89	deleterious	2,09	16,76	0,43	0,55	neutral	0,42	disease	0,68	neutral	0,39	disease	0,5	0	neutral	0,47	deleterious	0,57	NA	0	deleterious	0,56	medium_impact	-0,9	medium_impact	0,41	medium_impact	0,56	0,31	0,8	37,76	8,67	N	0,26	N	0,92	polymorphism	0,93	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10735	10735	A	G	MI.16251	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	266	89	Y	C	tAc/tGc	0,75	0,09	0	probably_damaging	0,94	neutral	0,18	neutral	1,92	deleterious	-4,04	deleterious	-7,88	high_impact	3,56	neutral	0,75	neutral	0,41	deleterious	3,6	23,2	0,5	0,6	disease	0,84	disease	0,84	disease	0,68	disease	0,81	6	neutral	0,96	neutral	0,12	deleterious	2	deleterious	0,82	low_impact	-1,9	medium_impact	-0,16	medium_impact	1,85	0,09	0,8	37,76	8,67	N	0,42	N	0,99	disease_causing	0,61	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10735	10735	A	C	MI.16252	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	266	89	Y	S	tAc/tCc	0,75	0,09	0	possibly_damaging	0,53	neutral	0,43	neutral	2,02	neutral	0,36	deleterious	-7,47	medium_impact	2,66	neutral	0,78	neutral	0,55	deleterious	2,19	17,43	0,41	0,5	disease	0,52	disease	0,73	disease	0,56	disease	0,68	4	neutral	0,57	neutral	0,45	NA	0	deleterious	0,58	medium_impact	-0,85	medium_impact	0,14	medium_impact	1,09	0,3	0,8	37,76	8,67	N	0,34	N	0,98	polymorphism	0,5	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10737	10737	G	C	MI.16253	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	268	90	V	L	Gta/Cta	-5,01	0	0	benign	0,17	neutral	1	neutral	1,74	neutral	-0,57	deleterious	-2,69	low_impact	1,02	neutral	0,69	neutral	0,56	neutral	-0,89	0,03	0,57	0,65	neutral	0,13	neutral	0,2	neutral	0,21	neutral	0,38	2	neutral	0,17	deleterious	0,92	neutral	-6	neutral	0,14	medium_impact	-0,17	high_impact	1,88	medium_impact	-0,28	0,73	0,85	22,45	16,15	N	0,28	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10737	10737	G	T	MI.16254	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	268	90	V	L	Gta/Tta	-5,01	0	0	benign	0,17	neutral	1	neutral	1,74	neutral	-0,57	deleterious	-2,69	low_impact	1,02	neutral	0,69	neutral	0,56	neutral	-0,79	0,05	0,57	0,65	neutral	0,13	neutral	0,2	neutral	0,21	neutral	0,38	2	neutral	0,17	deleterious	0,92	neutral	-6	neutral	0,14	medium_impact	-0,17	high_impact	1,88	medium_impact	-0,28	0,73	0,85	22,45	16,15	N	0,28	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10737	10737	G	A	MI.16255	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	268	90	V	M	Gta/Ata	-5,01	0	0	possibly_damaging	0,85	neutral	0,23	neutral	1,6	neutral	-2,97	deleterious	-2,84	medium_impact	2,12	neutral	0,71	neutral	0,51	deleterious	2,59	20,1	0,47	0,55	neutral	0,35	neutral	0,4	neutral	0,28	neutral	0,47	1	neutral	0,9	neutral	0,19	NA	0	deleterious	0,6	low_impact	-1,49	medium_impact	-0,08	medium_impact	0,64	0,64	0,8	22,45	16,15	N	0,43	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10738	10738	T	C	MI.16256	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	269	90	V	A	gTa/gCa	0,06	0,01	0	possibly_damaging	0,52	neutral	0,45	neutral	1,61	deleterious	-3,08	deleterious	-3,97	high_impact	3,89	neutral	0,72	neutral	0,57	deleterious	1,95	15,87	0,48	0,55	disease	0,5	disease	0,51	disease	0,61	disease	0,71	4	neutral	0,55	neutral	0,47	deleterious	1	deleterious	0,44	medium_impact	-0,84	medium_impact	0,16	high_impact	2,12	0,42	0,8	22,45	16,15	N	0,45	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10738	10738	T	A	MI.16257	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	269	90	V	E	gTa/gAa	0,06	0,01	0	probably_damaging	0,92	neutral	0,22	neutral	1,56	deleterious	-4,96	deleterious	-5,96	high_impact	3,89	neutral	0,68	neutral	0,37	deleterious	4,71	24,6	0,11	0,4	disease	0,77	disease	0,85	disease	0,73	disease	0,81	6	neutral	0,94	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-1,78	medium_impact	-0,1	high_impact	2,12	0,44	0,8	22,45	16,15	N	0,36	N	0,98	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10738	10738	T	G	MI.16258	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	269	90	V	G	gTa/gGa	0,06	0,01	0	probably_damaging	0,92	neutral	0,3	neutral	1,55	deleterious	-5	deleterious	-6,96	high_impact	3,89	neutral	0,68	neutral	0,49	deleterious	3,85	23,4	0,17	0,45	disease	0,76	disease	0,73	disease	0,64	disease	0,74	5	neutral	0,93	neutral	0,19	deleterious	2	deleterious	0,76	low_impact	-1,78	medium_impact	0,01	high_impact	2,12	0,4	0,8	22,45	16,15	N	0,38	N	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10740	10740	C	G	MI.16259	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	271	91	H	D	Cat/Gat	-4,78	0	0	benign	0,12	neutral	0,22	neutral	2,12	neutral	2,05	neutral	-1,7	neutral_impact	0,55	neutral	0,83	neutral	0,46	deleterious	2,26	17,9	0,5	0,6	neutral	0,18	disease	0,67	disease	0,53	disease	0,64	3	neutral	0,75	deleterious	0,55	neutral	-6	neutral	0,22	medium_impact	-0,01	medium_impact	-0,1	medium_impact	-0,68	0,63	0,8	22,45	17,54	N	0,31	N	0,6	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8452	8452	A	C	MI.1626	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	87	29	L	F	ttA/ttC	-0,8	0	0	probably_damaging	0,95	neutral	0,71	neutral	-0,14	deleterious	-5,58	neutral	-1,96	high_impact	3,5	neutral	0,98	damaging	0,23	deleterious	2,1	16,85	0,56070775	0,85	neutral	0,5	neutral	0,27	neutral	0,4	neutral	0,14	7	neutral	0,94	neutral	0,38	deleterious	2	deleterious	0,73	low_impact	-1,97	medium_impact	0,51	medium_impact	1,9	0,44	0,85	5,88	10,73	N	0,36	N	0,45	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10740	10740	C	T	MI.16260	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	271	91	H	Y	Cat/Tat	-4,78	0	0	benign	0,37	neutral	1	neutral	1,98	neutral	-1,02	neutral	-1,95	low_impact	1,04	neutral	0,83	neutral	0,54	deleterious	3,5	23,1	0,85	0,9	neutral	0,36	disease	0,58	disease	0,57	disease	0,71	4	neutral	0,37	deleterious	0,82	neutral	-6	neutral	0,36	medium_impact	-0,59	high_impact	1,88	medium_impact	-0,27	0,48	0,8	22,45	17,54	N	0,21	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10740	10740	C	A	MI.16261	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	271	91	H	N	Cat/Aat	-4,78	0	0	benign	0	neutral	0,35	neutral	2,07	neutral	1,51	neutral	-1,29	neutral_impact	-0,94	neutral	0,86	neutral	0,85	deleterious	2,1	16,85	0,84	0,85	neutral	0,18	disease	0,56	neutral	0,37	neutral	0,44	1	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,06	low_impact	-1,93	0,67	0,85	22,45	17,54	N	0,32	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10741	10741	A	C	MI.16262	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	272	91	H	P	cAt/cCt	0,52	0,09	0	possibly_damaging	0,5	neutral	0,2	neutral	1,98	neutral	-0,9	deleterious	-2,5	low_impact	1,25	neutral	0,75	neutral	0,4	deleterious	2,93	22	0,32	0,5	neutral	0,32	disease	0,87	disease	0,68	disease	0,82	6	neutral	0,78	neutral	0,35	neutral	-3	neutral	0,42	medium_impact	-0,8	medium_impact	-0,12	medium_impact	-0,09	0,54	0,8	22,45	17,54	N	0,39	N	0,8	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10741	10741	A	G	MI.16263	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	272	91	H	R	cAt/cGt	0,52	0,09	0	benign	0,12	neutral	0,37	neutral	2,06	neutral	1,44	neutral	-0,66	neutral_impact	0,78	neutral	0,77	neutral	0,63	neutral	1,2	11,74	0,88	0,9	neutral	0,16	disease	0,63	neutral	0,47	disease	0,51	0	neutral	0,57	deleterious	0,63	neutral	-6	neutral	0,21	medium_impact	-0,01	medium_impact	0,08	medium_impact	-0,48	0,39	0,8	22,45	17,54	N	0,35	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10741	10741	A	T	MI.16264	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	272	91	H	L	cAt/cTt	0,52	0,09	0	benign	0,18	neutral	0,68	neutral	2	neutral	-0,17	deleterious	-3,65	neutral_impact	0,24	neutral	0,8	neutral	0,54	deleterious	2,04	16,47	0,52	0,6	neutral	0,21	disease	0,69	disease	0,55	disease	0,71	4	neutral	0,2	deleterious	0,75	neutral	-6	neutral	0,25	medium_impact	-0,2	medium_impact	0,39	medium_impact	-0,94	0,48	0,8	22,45	17,54	N	0,25	N	0,76	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10742	10742	T	G	MI.16265	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	273	91	H	Q	caT/caG	5,6	0,85	0	benign	0,01	neutral	0,39	neutral	2,21	neutral	2,8	neutral	2,31	neutral_impact	-2,24	neutral	0,87	neutral	0,98	neutral	-0,98	0,02	0,9	0,95	neutral	0,18	neutral	0,11	neutral	0,31	neutral	0,23	5	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,1	medium_impact	1,03	medium_impact	0,1	low_impact	-3,02	0,59	0,8	22,45	17,54	N	0,46	N	0,06	polymorphism	0,62	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10742	10742	T	A	MI.16266	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	273	91	H	Q	caT/caA	5,6	0,85	0	benign	0,01	neutral	0,39	neutral	2,21	neutral	2,8	neutral	2,31	neutral_impact	-2,24	neutral	0,87	neutral	0,98	neutral	-0,81	0,04	0,9	0,95	neutral	0,18	neutral	0,11	neutral	0,31	neutral	0,23	5	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,1	medium_impact	1,03	medium_impact	0,1	low_impact	-3,02	0,59	0,8	22,45	17,54	N	0,46	N	0,06	polymorphism	0,62	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10743	10743	A	T	MI.16267	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	274	92	N	Y	Aac/Tac	-0,17	0,57	0	probably_damaging	1	neutral	1	neutral	1,84	deleterious	-3,41	deleterious	-7,58	high_impact	4,06	neutral	0,74	damaging	0,08	deleterious	3,69	23,3	0,62	0,65	disease	0,8	disease	0,87	disease	0,68	disease	0,78	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,86	low_impact	-3,55	high_impact	1,88	high_impact	2,27	0,27	0,8	53,06	11,8	N	0,33	N	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10743	10743	A	G	MI.16268	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	274	92	N	D	Aac/Gac	-0,17	0,57	0	probably_damaging	1	neutral	0,27	neutral	1,9	neutral	0,01	deleterious	-4,72	medium_impact	3,09	neutral	0,72	damaging	0,09	deleterious	3,88	23,5	0,92	0,95	neutral	0,45	disease	0,76	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,78	low_impact	-3,55	medium_impact	-0,03	medium_impact	1,45	0,58	0,8	53,06	11,8	N	0,33	N	0,96	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10743	10743	A	C	MI.16269	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	274	92	N	H	Aac/Cac	-0,17	0,57	0	probably_damaging	1	neutral	0,53	neutral	1,86	neutral	-2,57	deleterious	-4,74	high_impact	4,06	neutral	0,75	damaging	0,08	deleterious	3,14	22,6	0,83	0,85	disease	0,73	disease	0,81	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,55	medium_impact	0,24	high_impact	2,27	0,32	0,8	53,06	11,8	N	0,3	N	0,99	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8452	8452	A	T	MI.1627	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	87	29	L	F	ttA/ttT	-0,8	0	0	probably_damaging	0,95	neutral	0,71	neutral	-0,14	deleterious	-5,58	neutral	-1,96	high_impact	3,5	neutral	0,98	damaging	0,23	deleterious	2,23	17,72	0,56070775	0,85	neutral	0,5	neutral	0,27	neutral	0,4	neutral	0,14	7	neutral	0,94	neutral	0,38	deleterious	2	deleterious	0,73	low_impact	-1,97	medium_impact	0,51	medium_impact	1,9	0,44	0,85	5,88	10,73	N	0,36	N	0,45	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10744	10744	A	G	MI.16270	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	275	92	N	S	aAc/aGc	4,67	0,98	0	probably_damaging	1	neutral	0,78	neutral	2,04	neutral	0,02	deleterious	-4,6	low_impact	1,14	neutral	0,78	neutral	0,83	deleterious	2,13	17,04	0,89	0,9	neutral	0,14	neutral	0,5	neutral	0,36	neutral	0,4	2	deleterious	1	neutral	0,39	neutral	-2	deleterious	0,72	low_impact	-3,55	medium_impact	0,52	medium_impact	-0,18	0,19	0,8	53,06	11,8	N	0,41	N	0,89	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10744	10744	A	C	MI.16271	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	275	92	N	T	aAc/aCc	4,67	0,98	0	probably_damaging	1	neutral	0,47	neutral	1,89	neutral	-1,53	deleterious	-5,6	medium_impact	2,35	neutral	0,76	damaging	0,22	deleterious	3,45	23	0,81	0,85	neutral	0,5	disease	0,73	neutral	0,42	disease	0,56	1	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,78	low_impact	-3,55	medium_impact	0,18	medium_impact	0,83	0,31	0,8	53,06	11,8	N	0,48	N	0,95	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10744	10744	A	T	MI.16272	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	275	92	N	I	aAc/aTc	4,67	0,98	0	probably_damaging	1	neutral	0,43	neutral	1,87	deleterious	-3,04	deleterious	-8,52	medium_impact	2,75	neutral	0,73	damaging	0,09	deleterious	4,06	23,7	0,64	0,7	disease	0,75	disease	0,85	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,84	low_impact	-3,55	medium_impact	0,14	medium_impact	1,17	0,2	0,8	53,06	11,8	N	0,48	N	0,98	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10745	10745	C	G	MI.16273	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	276	92	N	K	aaC/aaG	2,37	0,94	0	probably_damaging	1	neutral	0,46	neutral	1,96	neutral	-0,67	deleterious	-5,66	high_impact	3,51	neutral	0,67	damaging	0,08	deleterious	4,13	23,8	0,94	0,95	disease	0,51	disease	0,86	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,84	low_impact	-3,55	medium_impact	0,17	medium_impact	1,8	0,48	0,8	53,06	11,8	N	0,38	N	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10745	10745	C	A	MI.16274	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	276	92	N	K	aaC/aaA	2,37	0,94	0	probably_damaging	1	neutral	0,46	neutral	1,96	neutral	-0,67	deleterious	-5,66	high_impact	3,51	neutral	0,67	damaging	0,08	deleterious	4,6	24,4	0,94	0,95	disease	0,51	disease	0,86	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,84	low_impact	-3,55	medium_impact	0,17	medium_impact	1,8	0,48	0,8	53,06	11,8	N	0,38	N	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10746	10746	C	G	MI.16275	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	277	93	L	V	Cta/Gta	-0,4	0	0	probably_damaging	1	neutral	0,35	neutral	1,53	neutral	-2,42	deleterious	-2,97	medium_impact	3,24	neutral	0,75	neutral	0,43	deleterious	3,49	23,1	0,59	0,65	neutral	0,5	disease	0,52	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,79	low_impact	-3,55	medium_impact	0,06	medium_impact	1,58	0,59	0,8	55,1	12,14	N	0,37	N	0,75	disease_causing	0,92	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10746	10746	C	A	MI.16276	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	277	93	L	M	Cta/Ata	-0,4	0	0	probably_damaging	1	neutral	0,17	neutral	1,51	neutral	-2,65	neutral	-1,98	medium_impact	2,46	neutral	0,76	neutral	0,62	deleterious	4,01	23,6	0,35	0,5	neutral	0,31	neutral	0,44	neutral	0,43	neutral	0,42	2	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,73	low_impact	-3,55	medium_impact	-0,17	medium_impact	0,92	0,75	0,85	55,1	12,14	N	0,44	N	0,77	disease_causing	0,91	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10747	10747	T	C	MI.16277	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	278	93	L	P	cTa/cCa	-0,17	0	0	probably_damaging	1	neutral	0,15	neutral	1,41	deleterious	-5,73	deleterious	-6,94	medium_impact	3,44	damaging	0,57	damaging	0,28	deleterious	2,51	19,53	0,27	0,45	disease	0,9	disease	0,83	disease	0,79	disease	0,87	7	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,91	low_impact	-3,55	medium_impact	-0,21	medium_impact	1,75	0,5	0,8	55,1	12,14	N	0,36	N	1	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10747	10747	T	A	MI.16278	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	278	93	L	Q	cTa/cAa	-0,17	0	0	probably_damaging	1	neutral	0,21	neutral	1,42	deleterious	-5,32	deleterious	-5,95	high_impact	4,34	neutral	0,69	neutral	0,3	deleterious	4,46	24,2	0,24	0,45	disease	0,86	disease	0,82	disease	0,7	disease	0,78	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,11	high_impact	2,5	0,64	0,8	55,1	12,14	N	0,39	N	0,99	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10747	10747	T	G	MI.16279	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	278	93	L	R	cTa/cGa	-0,17	0	0	probably_damaging	1	neutral	0,26	neutral	1,43	deleterious	-4,39	deleterious	-5,95	high_impact	4,34	damaging	0,57	damaging	0,23	deleterious	4,52	24,3	0,21	0,45	disease	0,87	disease	0,85	disease	0,79	disease	0,87	7	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,91	low_impact	-3,55	medium_impact	-0,04	high_impact	2,5	0,51	0,8	55,1	12,14	N	0,48	N	0,99	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8453	8453	A	G	MI.1628	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	88	30	N	D	Aac/Gac	-2,42	0	0	possibly_damaging	0,87	neutral	0,23	neutral	1,11	neutral	-2,83	neutral	-2,31	medium_impact	2,75	neutral	0,97	neutral	0,72	deleterious	2,35	18,5	0,84509432	0,9	neutral	0,32	neutral	0,39	neutral	0,45	neutral	0,18	6	neutral	0,91	neutral	0,18	NA	0	deleterious	0,68	low_impact	-1,54	medium_impact	-0,01	medium_impact	1,26	0,74	0,85	NA	NA	N	0,54	P	0,55	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10749	10749	A	T	MI.16280	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	280	94	N	Y	Aac/Tac	-6,86	0	0	probably_damaging	0,96	neutral	1	neutral	1,65	deleterious	-4,87	deleterious	-7,52	high_impact	4,38	neutral	0,67	neutral	0,28	deleterious	4,01	23,6	0,61	0,65	disease	0,79	disease	0,86	disease	0,71	disease	0,79	6	neutral	0,96	deleterious	0,52	deleterious	2	deleterious	0,84	low_impact	-2,07	high_impact	1,88	high_impact	2,53	0,46	0,8	50	10,05	N	0,36	N	0,99	disease_causing	0,84	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10749	10749	A	G	MI.16281	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	280	94	N	D	Aac/Gac	-6,86	0	0	possibly_damaging	0,64	neutral	0,21	neutral	1,71	neutral	-2,21	deleterious	-4,63	high_impact	3,69	neutral	0,7	neutral	0,37	deleterious	3,83	23,4	0,84	0,85	neutral	0,49	disease	0,75	disease	0,69	disease	0,7	4	neutral	0,81	neutral	0,29	deleterious	1	deleterious	0,63	low_impact	-1,03	medium_impact	-0,11	medium_impact	1,96	0,66	0,8	50	10,05	N	0,38	N	0,96	polymorphism	0,62	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10749	10749	A	C	MI.16282	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	280	94	N	H	Aac/Cac	-6,86	0	0	probably_damaging	0,96	neutral	0,54	neutral	1,66	deleterious	-4,01	deleterious	-4,71	high_impact	4,38	neutral	0,75	damaging	0,28	deleterious	3,38	22,9	0,76	0,8	disease	0,71	disease	0,79	disease	0,71	disease	0,74	5	neutral	0,96	neutral	0,29	deleterious	2	deleterious	0,82	low_impact	-2,07	medium_impact	0,25	high_impact	2,53	0,48	0,8	50	10,05	N	0,38	N	0,99	disease_causing	0,56	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10750	10750	A	C	MI.16283	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	281	94	N	T	aAc/aCc	6,75	1	0,01	possibly_damaging	0,64	neutral	0,4	neutral	1,76	deleterious	-3,01	deleterious	-5,45	medium_impact	2,94	neutral	0,73	neutral	0,57	deleterious	3,32	22,9	0,8	0,85	neutral	0,26	disease	0,8	neutral	0,49	disease	0,63	3	neutral	0,67	neutral	0,38	NA	0	deleterious	0,55	low_impact	-1,03	medium_impact	0,11	medium_impact	1,33	0,46	0,8	50	10,05	P	0,6	P	0,95	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10750	10750	A	T	MI.16284	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	281	94	N	I	aAc/aTc	6,75	1	0,01	probably_damaging	0,93	neutral	0,44	neutral	1,66	deleterious	-4,41	deleterious	-8,43	high_impact	3,84	neutral	0,74	neutral	0,45	deleterious	4,1	23,7	0,53	0,6	disease	0,71	disease	0,85	disease	0,66	disease	0,75	5	neutral	0,93	neutral	0,26	deleterious	2	deleterious	0,8	low_impact	-1,83	medium_impact	0,15	high_impact	2,08	0,35	0,8	50	10,05	P	0,67	P	0,98	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10750	10750	A	G	MI.16285	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	281	94	N	S	aAc/aGc	6,75	1	0,01	benign	0,08	neutral	0,51	neutral	1,82	neutral	-1,34	deleterious	-4,29	low_impact	1,41	neutral	0,82	neutral	0,54	deleterious	0,32	5,85	0,87	0,9	neutral	0,25	disease	0,61	neutral	0,45	neutral	0,43	1	neutral	0,42	deleterious	0,72	neutral	-6	neutral	0,24	medium_impact	0,17	medium_impact	0,22	medium_impact	0,04	0,28	0,8	50	10,05	N	0,48	N	0,89	disease_causing	1	0,09	rs372297272	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10751	10751	C	A	MI.16286	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	282	94	N	K	aaC/aaA	5,36	1	0	possibly_damaging	0,75	neutral	0,3	neutral	1,75	neutral	-2,52	deleterious	-5,54	medium_impact	2,76	neutral	0,74	neutral	0,42	deleterious	4,48	24,2	0,88	0,9	neutral	0,48	disease	0,83	disease	0,65	disease	0,68	4	neutral	0,81	neutral	0,28	NA	0	deleterious	0,63	low_impact	-1,24	medium_impact	0,01	medium_impact	1,18	0,51	0,8	50	10,05	P	0,58	P	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10751	10751	C	G	MI.16287	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	282	94	N	K	aaC/aaG	5,36	1	0	possibly_damaging	0,75	neutral	0,3	neutral	1,75	neutral	-2,52	deleterious	-5,54	medium_impact	2,76	neutral	0,74	neutral	0,42	deleterious	4,01	23,6	0,88	0,9	neutral	0,48	disease	0,83	disease	0,65	disease	0,68	4	neutral	0,81	neutral	0,28	NA	0	deleterious	0,63	low_impact	-1,24	medium_impact	0,01	medium_impact	1,18	0,51	0,8	50	10,05	P	0,57	P	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10752	10752	C	G	MI.16288	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	283	95	L	V	Cta/Gta	-0,86	0	0	benign	0,29	neutral	0,17	neutral	1,65	neutral	-1,58	deleterious	-2,59	medium_impact	2,81	neutral	0,82	neutral	0,42	deleterious	1,9	15,57	0,75	0,8	neutral	0,23	neutral	0,38	neutral	0,35	neutral	0,41	2	neutral	0,8	neutral	0,44	neutral	-3	neutral	0,21	medium_impact	-0,45	medium_impact	-0,17	medium_impact	1,22	0,49	0,8	56,12	12,6	N	0,42	N	0,75	disease_causing	0,94	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10752	10752	C	A	MI.16289	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	283	95	L	M	Cta/Ata	-0,86	0	0	possibly_damaging	0,68	neutral	0,1	neutral	1,57	deleterious	-3,01	neutral	-1,83	medium_impact	2,37	neutral	0,83	neutral	0,57	deleterious	3,94	23,5	0,53	0,6	disease	0,55	neutral	0,37	neutral	0,32	disease	0,54	1	neutral	0,91	neutral	0,21	NA	0	deleterious	0,53	low_impact	-1,1	medium_impact	-0,32	medium_impact	0,85	0,55	0,8	56,12	12,6	N	0,44	N	0,77	disease_causing	0,93	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8453	8453	A	T	MI.1629	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	88	30	N	Y	Aac/Tac	-2,42	0	0	probably_damaging	0,98	neutral	1	neutral	1,03	deleterious	-5,17	deleterious	-4,24	medium_impact	3,1	neutral	0,99	neutral	0,64	deleterious	3,58	23,2	0,46398601	0,85	disease	0,66	disease	0,5	disease	0,58	disease	0,58	2	neutral	0,98	deleterious	0,51	deleterious	1	deleterious	0,78	low_impact	-2,36	high_impact	1,98	medium_impact	1,56	0,59	0,85	NA	NA	N	0,32	N	0,68	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10753	10753	T	G	MI.16290	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	284	95	L	R	cTa/cGa	0,29	0,02	0	probably_damaging	0,98	neutral	0,1	neutral	1,57	deleterious	-5,19	deleterious	-5,73	high_impact	3,71	damaging	0,59	damaging	0,21	deleterious	4,48	24,2	0,49	0,55	disease	0,86	disease	0,77	disease	0,68	disease	0,77	5	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,86	low_impact	-2,35	medium_impact	-0,32	medium_impact	1,97	0,41	0,8	56,12	12,6	N	0,34	N	0,99	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10753	10753	T	C	MI.16291	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	284	95	L	P	cTa/cCa	0,29	0,02	0	probably_damaging	0,99	deleterious	0,04	neutral	1,54	deleterious	-5,79	deleterious	-6,6	medium_impact	3,5	damaging	0,56	damaging	0,23	deleterious	4,19	23,8	0,63	0,7	disease	0,88	disease	0,76	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,87	low_impact	-2,63	medium_impact	-0,56	medium_impact	1,8	0,44	0,8	56,12	12,6	N	0,3	N	1	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10753	10753	T	A	MI.16292	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	284	95	L	Q	cTa/cAa	0,29	0,02	0	probably_damaging	0,98	neutral	0,08	neutral	1,57	deleterious	-5,23	deleterious	-5,68	high_impact	4,4	neutral	0,68	neutral	0,3	deleterious	4,37	24,1	0,51	0,6	disease	0,86	disease	0,75	disease	0,63	disease	0,76	5	deleterious	0,99	neutral	0,05	deleterious	2	deleterious	0,83	low_impact	-2,35	medium_impact	-0,38	high_impact	2,55	0,41	0,8	56,12	12,6	N	0,42	N	0,99	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10755	10755	C	T	MI.16293	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	286	96	L	F	Ctc/Ttc	-12,39	0	0	possibly_damaging	0,5	neutral	0,13	neutral	1,36	deleterious	-4,29	deleterious	-3,53	high_impact	3,6	neutral	0,65	damaging	0,08	deleterious	3,85	23,4	0,6	0,65	disease	0,61	neutral	0,45	disease	0,62	disease	0,57	1	neutral	0,86	neutral	0,32	deleterious	1	deleterious	0,45	medium_impact	-0,8	medium_impact	-0,25	medium_impact	1,88	0,51	0,8	54,08	12,35	N	0,29	N	0,97	polymorphism	0,82	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10755	10755	C	G	MI.16294	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	286	96	L	V	Ctc/Gtc	-12,39	0	0	probably_damaging	0,92	neutral	0,1	neutral	1,42	deleterious	-3,31	deleterious	-2,89	medium_impact	3,43	damaging	0,58	damaging	0,05	deleterious	3,67	23,2	0,59	0,65	disease	0,52	neutral	0,34	disease	0,66	neutral	0,44	1	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,74	low_impact	-1,78	medium_impact	-0,32	medium_impact	1,74	0,49	0,8	54,08	12,35	N	0,33	N	0,75	polymorphism	0,96	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10755	10755	C	A	MI.16295	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	286	96	L	I	Ctc/Atc	-12,39	0	0	possibly_damaging	0,9	neutral	0,12	neutral	1,44	deleterious	-3,02	neutral	-1,9	medium_impact	3,43	neutral	0,6	damaging	0,06	deleterious	4,36	24,1	0,48	0,55	neutral	0,45	neutral	0,37	disease	0,65	neutral	0,44	1	neutral	0,96	neutral	0,11	NA	0	deleterious	0,72	low_impact	-1,68	medium_impact	-0,27	medium_impact	1,74	0,76	0,85	54,08	12,35	N	0,37	N	0,8	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10756	10756	T	C	MI.16296	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	287	96	L	P	cTc/cCc	0,29	0,02	0	probably_damaging	1	deleterious	0,02	neutral	1,32	deleterious	-6,88	deleterious	-6,82	high_impact	3,86	damaging	0,41	damaging	0,05	deleterious	4,23	23,9	0,38	0,5	disease	0,91	disease	0,69	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,55	medium_impact	-0,73	high_impact	2,1	0,45	0,8	54,08	12,35	P	0,49	N	1	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10756	10756	T	A	MI.16297	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	287	96	L	H	cTc/cAc	0,29	0,02	0	probably_damaging	1	neutral	0,06	neutral	1,33	deleterious	-7,06	deleterious	-6,69	medium_impact	3,16	damaging	0,59	damaging	0,05	deleterious	4,57	24,4	0,31	0,5	disease	0,93	disease	0,68	disease	0,64	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,86	low_impact	-3,55	medium_impact	-0,45	medium_impact	1,51	0,64	0,8	54,08	12,35	N	0,27	N	1	disease_causing	0,84	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10756	10756	T	G	MI.16298	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	287	96	L	R	cTc/cGc	0,29	0,02	0	probably_damaging	1	neutral	0,06	neutral	1,33	deleterious	-6,15	deleterious	-5,83	high_impact	4,41	damaging	0,47	damaging	0,04	deleterious	4,46	24,2	0,32	0,5	disease	0,89	disease	0,72	disease	0,69	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,45	high_impact	2,56	0,57	0,8	54,08	12,35	N	0,43	N	0,99	disease_causing	0,9	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10758	10758	C	G	MI.16299	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	289	97	Q	E	Caa/Gaa	-1,32	0	0	probably_damaging	1	neutral	0,27	neutral	1,97	neutral	-0,24	deleterious	-2,65	medium_impact	3,08	neutral	0,67	neutral	0,32	deleterious	3,13	22,6	0,76	0,8	neutral	0,2	neutral	0,49	neutral	0,46	neutral	0,45	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,73	low_impact	-3,55	medium_impact	-0,03	medium_impact	1,44	0,81	0,85	58,16	11,18	N	0,43	N	0,91	disease_causing	0,93	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8602	8602	T	G	MI.163	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	76	26	F	V	Ttt/Gtt	-2,65	0	0,01	benign	0,09	neutral	0,07	neutral	4,36	neutral	-0,26	deleterious	-3,14	low_impact	1,38	neutral	0,87	neutral	0,59	deleterious	0,75	9,18	0,32	0,65	disease	0,51	disease	0,56	neutral	0,38	neutral	0,5	0	neutral	0,92	deleterious	0,49	neutral	-6	neutral	0,22	medium_impact	0,2	medium_impact	-0,34	medium_impact	0,09	0,34	0,9	15,49	8,03	N	0,39	N	0,98	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8453	8453	A	C	MI.1630	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	88	30	N	H	Aac/Cac	-2,42	0	0	probably_damaging	0,98	neutral	0,54	neutral	1,14	neutral	-2,47	deleterious	-2,62	medium_impact	3,1	neutral	0,99	neutral	0,52	deleterious	2,91	21,9	0,66000491	0,85	disease	0,54	neutral	0,48	disease	0,58	neutral	0,43	1	neutral	0,97	neutral	0,28	deleterious	1	deleterious	0,75	low_impact	-2,36	medium_impact	0,33	medium_impact	1,56	0,7	0,85	NA	NA	N	0,38	N	0,41	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10758	10758	C	A	MI.16300	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	289	97	Q	K	Caa/Aaa	-1,32	0	0	probably_damaging	1	neutral	0,34	neutral	2,05	neutral	0,32	deleterious	-3,17	low_impact	1,6	neutral	0,82	neutral	0,84	deleterious	2,94	22	0,8	0,85	neutral	0,17	neutral	0,48	neutral	0,41	neutral	0,41	2	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,73	low_impact	-3,55	medium_impact	0,05	medium_impact	0,2	0,79	0,85	58,16	11,18	N	0,34	N	0,92	disease_causing	0,96	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10759	10759	A	G	MI.16301	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	290	97	Q	R	cAa/cGa	4,21	1	0	probably_damaging	1	neutral	0,36	neutral	2,08	neutral	0,48	deleterious	-3,28	medium_impact	2,76	neutral	0,83	neutral	0,67	deleterious	3,5	23,1	0,8	0,85	neutral	0,3	disease	0,51	disease	0,54	neutral	0,44	1	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	0,07	medium_impact	1,18	0,65	0,8	58,16	11,18	P	0,55	P	0,72	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10759	10759	A	C	MI.16302	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	290	97	Q	P	cAa/cCa	4,21	1	0	probably_damaging	1	neutral	0,2	neutral	1,81	deleterious	-3,41	deleterious	-5,34	high_impact	4,12	neutral	0,66	neutral	0,28	deleterious	3,58	23,2	0,66	0,7	disease	0,61	disease	0,71	disease	0,53	disease	0,6	2	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,82	low_impact	-3,55	medium_impact	-0,12	high_impact	2,32	0,53	0,8	58,16	11,18	P	0,6	P	0,93	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10759	10759	A	T	MI.16303	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	290	97	Q	L	cAa/cTa	4,21	1	0	probably_damaging	1	neutral	0,76	neutral	1,82	neutral	-2,72	deleterious	-6,45	medium_impact	2,73	neutral	0,65	neutral	0,33	deleterious	4,01	23,6	0,47	0,55	disease	0,53	disease	0,65	disease	0,52	disease	0,57	1	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,77	low_impact	-3,55	medium_impact	0,49	medium_impact	1,15	0,51	0,8	58,16	11,18	N	0,43	N	0,95	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10760	10760	A	C	MI.16304	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	291	97	Q	H	caA/caC	5,6	1	0	probably_damaging	1	neutral	0,53	neutral	1,82	deleterious	-3,11	deleterious	-4,54	high_impact	3,77	neutral	0,7	damaging	0,26	deleterious	3,08	22,5	0,76	0,8	disease	0,55	disease	0,55	disease	0,58	disease	0,64	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,78	low_impact	-3,55	medium_impact	0,24	high_impact	2,02	0,7	0,85	58,16	11,18	P	0,61	P	0,8	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10760	10760	A	T	MI.16305	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	291	97	Q	H	caA/caT	5,6	1	0	probably_damaging	1	neutral	0,53	neutral	1,82	deleterious	-3,11	deleterious	-4,54	high_impact	3,77	neutral	0,7	damaging	0,26	deleterious	3,12	22,6	0,76	0,8	disease	0,55	disease	0,55	disease	0,58	disease	0,64	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,78	low_impact	-3,55	medium_impact	0,24	high_impact	2,02	0,7	0,85	58,16	11,18	P	0,61	P	0,8	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10761	10761	T	A	MI.16306	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	292	98	C	S	Tgc/Agc	5,6	1	0	probably_damaging	1	neutral	0,36	neutral	1,89	deleterious	-3,58	deleterious	-9,79	high_impact	3,83	damaging	0,56	damaging	0,03	deleterious	3,89	23,5	0,31	0,45	NA	NA	disease	0,72	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,93	low_impact	-3,55	medium_impact	0,07	high_impact	2,07	0,3	0,8	NA	NA	P	0,59	P	0,97	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10761	10761	T	C	MI.16307	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	292	98	C	R	Tgc/Cgc	5,6	1	0	probably_damaging	1	neutral	0,43	neutral	1,97	deleterious	-4,99	deleterious	-11,75	high_impact	4,04	neutral	0,63	damaging	0,05	deleterious	3,76	23,3	0,26	0,45	NA	NA	disease	0,8	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,94	low_impact	-3,55	medium_impact	0,14	high_impact	2,25	0,17	0,8	NA	NA	N	0,54	P	1	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10761	10761	T	G	MI.16308	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	292	98	C	G	Tgc/Ggc	5,6	1	0	probably_damaging	1	neutral	0,31	neutral	2	deleterious	-4,1	deleterious	-11,76	high_impact	4,04	damaging	0,57	damaging	0,04	deleterious	3,53	23,1	0,25	0,45	NA	NA	disease	0,72	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,93	low_impact	-3,55	medium_impact	0,02	high_impact	2,25	0,24	0,8	NA	NA	P	0,57	P	1	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10762	10762	G	T	MI.16309	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	293	98	C	F	tGc/tTc	7,44	1	0	probably_damaging	1	neutral	0,63	neutral	1,83	deleterious	-5,05	deleterious	-10,71	medium_impact	3,28	damaging	0,55	damaging	0,03	deleterious	4,07	23,7	0,25	0,45	NA	NA	disease	0,82	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,94	low_impact	-3,55	medium_impact	0,34	medium_impact	1,61	0,3	0,8	NA	NA	N	0,46	N	0,99	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8454	8454	A	C	MI.1631	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	89	30	N	T	aAc/aCc	-0,33	0	0	probably_damaging	0,92	neutral	0,43	neutral	1,08	deleterious	-3,41	deleterious	-2,84	low_impact	1,48	neutral	1	neutral	0,76	deleterious	2,16	17,24	0,72936886	0,85	neutral	0,39	neutral	0,44	neutral	0,28	neutral	0,24	5	neutral	0,92	neutral	0,26	neutral	-2	deleterious	0,71	low_impact	-1,76	medium_impact	0,22	medium_impact	0,17	0,69	0,85	NA	NA	N	0,49	N	0,38	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10762	10762	G	C	MI.16310	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	293	98	C	S	tGc/tCc	7,44	1	0	probably_damaging	1	neutral	0,36	neutral	1,89	deleterious	-3,58	deleterious	-9,79	high_impact	3,83	damaging	0,56	damaging	0,03	deleterious	3,32	22,9	0,31	0,45	NA	NA	disease	0,72	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,93	low_impact	-3,55	medium_impact	0,07	high_impact	2,07	0,3	0,8	NA	NA	P	0,58	P	0,97	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10762	10762	G	A	MI.16311	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	293	98	C	Y	tGc/tAc	7,44	1	0	probably_damaging	1	neutral	0,86	neutral	1,83	deleterious	-5,47	deleterious	-10,66	medium_impact	3,48	damaging	0,57	damaging	0,03	deleterious	3,86	23,5	0,25	0,45	NA	NA	disease	0,83	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,43	deleterious	1	deleterious	0,93	low_impact	-3,55	medium_impact	0,65	medium_impact	1,78	0,26	0,8	NA	NA	N	0,44	N	0,99	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10763	10763	C	A	MI.16312	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	294	98	C	W	tgC/tgA	9,05	1	0	probably_damaging	1	neutral	0,16	neutral	1,84	deleterious	-7,11	deleterious	-10,7	medium_impact	2,81	neutral	0,62	damaging	0,03	deleterious	4,69	24,6	0,22	0,45	NA	NA	disease	0,82	disease	0,76	disease	0,76	5	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,93	low_impact	-3,55	medium_impact	-0,19	medium_impact	1,22	0,26	0,8	NA	NA	N	0,45	N	0,99	disease_causing	1	0,2	rs28532881	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10763	10763	C	G	MI.16313	MT-ND4L	I	ENSG00000212907	ENSP00000354728	ENST00000361335	NU4LM_HUMAN	P03901	4539	YP_003024034.1	294	98	C	W	tgC/tgG	9,05	1	0	probably_damaging	1	neutral	0,16	neutral	1,84	deleterious	-7,11	deleterious	-10,7	medium_impact	2,81	neutral	0,62	damaging	0,03	deleterious	4,46	24,2	0,22	0,45	NA	NA	disease	0,82	disease	0,76	disease	0,76	5	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,93	low_impact	-3,55	medium_impact	-0,19	medium_impact	1,22	0,26	0,8	NA	NA	N	0,45	N	0,99	disease_causing	1	0,2	rs28532881	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10760	10760	A	C	MI.16314	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1	1	M	L	Atg/Ctg	5,6	1	0	probably_damaging	0,98	deleterious	0	neutral	0,26	deleterious	-3,7	neutral	-2,2	NA	NA	neutral	0,61	damaging	0,11	deleterious	3,08	22,5	0,04	0,35	NA	NA	neutral	0,27	disease	0,65	neutral	0,39	2	deleterious	1	neutral	0,01	deleterious	4	deleterious	0,62	NA	NA	NA	NA	NA	NA	0,41	0,8	47,06	9,42	P	0,63	P	0,98	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10760	10760	A	T	MI.16315	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1	1	M	L	Atg/Ttg	5,6	1	0	probably_damaging	0,98	deleterious	0	neutral	0,26	deleterious	-3,7	neutral	-2,2	NA	NA	neutral	0,61	damaging	0,11	deleterious	3,12	22,6	0,04	0,35	NA	NA	neutral	0,27	disease	0,65	neutral	0,39	2	deleterious	1	neutral	0,01	deleterious	4	deleterious	0,62	NA	NA	NA	NA	NA	NA	0,41	0,8	47,06	9,42	P	0,63	P	0,98	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10761	10761	T	C	MI.16316	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	2	1	M	T	aTg/aCg	5,6	1	0	probably_damaging	1	deleterious	0	neutral	0,08	deleterious	-7,2	deleterious	-4,41	NA	NA	neutral	0,67	damaging	0,13	deleterious	3,76	23,3	0,07	0,35	NA	NA	neutral	0,39	disease	0,67	neutral	0,4	2	deleterious	1	neutral	0	deleterious	4	deleterious	0,8	NA	NA	NA	NA	NA	NA	0,06	0,8	47,06	9,42	P	0,54	P	0,99	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10761	10761	T	A	MI.16317	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	2	1	M	K	aTg/aAg	5,6	1	0	probably_damaging	1	deleterious	0	neutral	0,08	deleterious	-7,83	deleterious	-4,41	NA	NA	neutral	0,64	damaging	0,11	deleterious	3,89	23,5	0,05	0,35	NA	NA	neutral	0,49	disease	0,69	disease	0,61	2	deleterious	1	neutral	0	deleterious	4	deleterious	0,82	NA	NA	NA	NA	NA	NA	0,15	0,8	47,06	9,42	P	0,55	P	1	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10762	10762	G	T	MI.16318	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	3	1	M	I	atG/atT	7,44	1	0	probably_damaging	0,99	deleterious	0	neutral	0,14	deleterious	-5,15	deleterious	-2,94	NA	NA	neutral	0,65	damaging	0,13	deleterious	4,07	23,7	0,06	0,35	NA	NA	neutral	0,34	disease	0,67	neutral	0,39	2	deleterious	1	neutral	0,01	deleterious	4	deleterious	0,74	NA	NA	NA	NA	NA	NA	0,42	0,8	47,06	9,42	P	0,56	P	0,95	NA	NA	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10762	10762	G	C	MI.16319	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	3	1	M	I	atG/atC	7,44	1	0	probably_damaging	0,99	deleterious	0	neutral	0,14	deleterious	-5,15	deleterious	-2,94	NA	NA	neutral	0,65	damaging	0,13	deleterious	3,32	22,9	0,06	0,35	NA	NA	neutral	0,34	disease	0,67	neutral	0,39	2	deleterious	1	neutral	0,01	deleterious	4	deleterious	0,74	NA	NA	NA	NA	NA	NA	0,42	0,8	47,06	9,42	P	0,56	P	0,95	NA	NA	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8454	8454	A	T	MI.1632	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	89	30	N	I	aAc/aTc	-0,33	0	0	probably_damaging	0,98	neutral	0,43	neutral	1,03	deleterious	-6,07	deleterious	-4,71	medium_impact	2,56	neutral	0,99	neutral	0,54	deleterious	3,72	23,3	0,47385093	0,85	disease	0,61	disease	0,51	disease	0,53	disease	0,51	0	neutral	0,98	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-2,36	medium_impact	0,22	medium_impact	1,1	0,45	0,85	NA	NA	N	0,48	N	0,68	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10763	10763	C	G	MI.16320	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	4	2	L	V	Cta/Gta	9,05	1	0	possibly_damaging	0,86	deleterious	0,01	neutral	0,86	deleterious	-3,36	neutral	-2,19	medium_impact	3,31	neutral	0,67	neutral	0,48	deleterious	4,46	24,2	0,22	0,45	NA	NA	neutral	0,21	neutral	0,38	neutral	0,23	5	deleterious	0,99	neutral	0,08	deleterious	4	deleterious	0,77	low_impact	-1,46	medium_impact	-0,92	high_impact	2,15	0,46	0,8	46,84	9,11	P	0,65	P	0,89	polymorphism	1	0,12	rs28532881	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10763	10763	C	A	MI.16321	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	4	2	L	M	Cta/Ata	9,05	1	0	probably_damaging	0,98	neutral	0,11	neutral	0,88	deleterious	-3,11	neutral	-1,46	medium_impact	2,96	neutral	0,65	neutral	0,58	deleterious	4,69	24,6	0,16	0,45	NA	NA	neutral	0,15	neutral	0,19	neutral	0,23	5	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,74	low_impact	-2,31	medium_impact	-0,31	medium_impact	1,8	0,41	0,8	46,84	9,11	P	0,67	P	0,9	polymorphism	1	0,02	rs28532881	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10764	10764	T	G	MI.16322	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	5	2	L	R	cTa/cGa	-0,86	0,02	0	probably_damaging	0,98	deleterious	0	neutral	0,78	deleterious	-5,66	deleterious	-4,4	medium_impact	3,31	damaging	0,55	neutral	0,35	deleterious	3,94	23,5	0,11	0,4	NA	NA	disease	0,53	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,86	low_impact	-2,31	low_impact	-1,48	high_impact	2,15	0,17	0,8	46,84	9,11	N	0,37	N	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10764	10764	T	A	MI.16323	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	5	2	L	Q	cTa/cAa	-0,86	0,02	0	probably_damaging	0,99	deleterious	0	neutral	0,77	deleterious	-5,77	deleterious	-4,4	medium_impact	3,31	damaging	0,57	neutral	0,4	deleterious	3,83	23,4	0,18	0,45	NA	NA	neutral	0,39	neutral	0,44	neutral	0,19	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-2,59	low_impact	-1,48	high_impact	2,15	0,24	0,8	46,84	9,11	N	0,43	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10764	10764	T	C	MI.16324	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	5	2	L	P	cTa/cCa	-0,86	0,02	0	probably_damaging	0,99	deleterious	0	neutral	0,77	deleterious	-6,28	deleterious	-5,13	medium_impact	3,31	damaging	0,53	neutral	0,39	deleterious	3,67	23,2	0,15	0,45	NA	NA	neutral	0,37	disease	0,68	neutral	0,41	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-2,59	low_impact	-1,48	high_impact	2,15	0,28	0,8	46,84	9,11	N	0,38	N	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10766	10766	A	G	MI.16325	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	7	3	K	E	Aaa/Gaa	8,59	1	0	probably_damaging	1	deleterious	0	neutral	1,22	neutral	-2,3	deleterious	-2,93	medium_impact	3,31	damaging	0,56	damaging	0,09	deleterious	3,8	23,4	0,21	0,45	NA	NA	neutral	0,48	neutral	0,5	neutral	0,35	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,8	low_impact	-3,54	low_impact	-1,48	high_impact	2,15	0,55	0,8	47,93	9,67	P	0,58	P	0,87	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10766	10766	A	C	MI.16326	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	7	3	K	Q	Aaa/Caa	8,59	1	0	probably_damaging	1	deleterious	0	neutral	1,18	neutral	-2,93	deleterious	-2,93	medium_impact	3,31	damaging	0,55	damaging	0,1	deleterious	3,25	22,8	0,35	0,5	NA	NA	neutral	0,37	neutral	0,48	neutral	0,19	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	2,15	0,41	0,8	47,93	9,67	P	0,59	P	0,86	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10767	10767	A	T	MI.16327	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	8	3	K	M	aAa/aTa	8,59	1	0	probably_damaging	1	neutral	0,05	neutral	1,15	deleterious	-3,62	deleterious	-4,39	medium_impact	2,34	damaging	0,54	damaging	0,14	deleterious	3,6	23,2	0,17	0,45	NA	NA	neutral	0,4	neutral	0,39	neutral	0,18	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,19	0,18	0,8	47,93	9,67	P	0,62	P	0,42	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10767	10767	A	C	MI.16328	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	8	3	K	T	aAa/aCa	8,59	1	0	probably_damaging	1	deleterious	0,04	neutral	1,21	neutral	-2,35	deleterious	-4,39	medium_impact	2,5	damaging	0,56	damaging	0,13	deleterious	3,39	23	0,24	0,45	NA	NA	neutral	0,34	neutral	0,42	neutral	0,18	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,35	0,17	0,8	47,93	9,67	P	0,62	P	0,77	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10768	10768	A	T	MI.16329	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	9	3	K	N	aaA/aaT	5,6	1	0	probably_damaging	1	deleterious	0,02	neutral	1,18	neutral	-2,97	deleterious	-3,66	medium_impact	3,31	neutral	0,63	damaging	0,09	deleterious	3,66	23,2	0,5	0,6	NA	NA	neutral	0,34	neutral	0,49	neutral	0,19	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-3,54	medium_impact	-0,75	high_impact	2,15	0,37	0,8	47,93	9,67	P	0,64	P	0,72	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8454	8454	A	G	MI.1633	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	89	30	N	S	aAc/aGc	-0,33	0	0	possibly_damaging	0,87	neutral	0,47	neutral	1,14	neutral	-2,4	neutral	-1,77	low_impact	0,96	neutral	1	neutral	0,94	neutral	1,57	13,68	0,91929012	0,95	neutral	0,2	neutral	0,23	neutral	0,28	neutral	0,15	7	neutral	0,86	neutral	0,3	neutral	-3	deleterious	0,65	low_impact	-1,54	medium_impact	0,26	medium_impact	-0,28	0,43	0,85	NA	NA	N	0,48	N	0,03	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10768	10768	A	C	MI.16330	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	9	3	K	N	aaA/aaC	5,6	1	0	probably_damaging	1	deleterious	0,02	neutral	1,18	neutral	-2,97	deleterious	-3,66	medium_impact	3,31	neutral	0,63	damaging	0,09	deleterious	3,61	23,2	0,5	0,6	NA	NA	neutral	0,34	neutral	0,49	neutral	0,19	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-3,54	medium_impact	-0,75	high_impact	2,15	0,37	0,8	47,93	9,67	P	0,64	P	0,72	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10769	10769	C	G	MI.16331	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	10	4	L	V	Cta/Gta	5,6	1	0	benign	0,32	neutral	0,3	neutral	1,45	neutral	-1,05	neutral	0,5	neutral_impact	-0,04	neutral	0,74	neutral	0,88	deleterious	1,96	15,95	0,26	0,45	NA	NA	neutral	0,1	neutral	0,16	neutral	0,26	5	neutral	0,64	deleterious	0,49	neutral	-6	deleterious	0,71	medium_impact	-0,41	medium_impact	0	low_impact	-1,17	0,47	0,8	27,67	29,01	P	0,66	P	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10769	10769	C	A	MI.16332	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	10	4	L	M	Cta/Ata	5,6	1	0	benign	0,11	neutral	0,07	neutral	1,38	neutral	-2,11	neutral	-0,55	neutral_impact	-0,39	neutral	0,75	neutral	0,86	deleterious	2,63	20,4	0,19	0,45	NA	NA	neutral	0,12	neutral	0,26	neutral	0,25	5	neutral	0,92	deleterious	0,48	neutral	-6	deleterious	0,72	medium_impact	0,14	medium_impact	-0,43	low_impact	-1,51	0,35	0,8	27,67	29,01	P	0,62	P	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10770	10770	T	A	MI.16333	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	11	4	L	Q	cTa/cAa	0,29	0,94	0	probably_damaging	0,9	deleterious	0	neutral	1,33	deleterious	-3,73	deleterious	-3,21	low_impact	1,2	neutral	0,67	neutral	0,6	deleterious	4,08	23,7	0,2	0,45	NA	NA	neutral	0,28	neutral	0,49	neutral	0,16	7	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,76	low_impact	-1,61	low_impact	-1,48	medium_impact	0,06	0,22	0,8	27,67	29,01	N	0,45	N	0,72	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10770	10770	T	G	MI.16334	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	11	4	L	R	cTa/cGa	0,29	0,94	0	probably_damaging	0,9	deleterious	0	neutral	1,34	deleterious	-3,56	deleterious	-3,38	low_impact	1,2	neutral	0,63	neutral	0,55	deleterious	4,06	23,7	0,16	0,45	NA	NA	disease	0,63	disease	0,62	disease	0,74	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,84	low_impact	-1,61	low_impact	-1,48	medium_impact	0,06	0,23	0,8	27,67	29,01	N	0,37	N	0,78	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10770	10770	T	C	MI.16335	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	11	4	L	P	cTa/cCa	0,29	0,94	0	probably_damaging	0,95	deleterious	0	neutral	1,33	deleterious	-4,14	deleterious	-3,44	low_impact	1,2	damaging	0,58	neutral	0,44	deleterious	3,84	23,4	0,15	0,4	NA	NA	disease	0,56	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,83	low_impact	-1,92	low_impact	-1,48	medium_impact	0,06	0,21	0,8	27,67	29,01	N	0,4	N	0,86	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10772	10772	A	G	MI.16336	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	13	5	I	V	Atc/Gtc	-3,17	0	0	benign	0,05	neutral	0,08	neutral	1,37	neutral	-1,47	neutral	-0,67	low_impact	1,77	neutral	0,8	neutral	0,71	deleterious	0	2,58	0,32	0,5	NA	NA	neutral	0,12	neutral	0,33	neutral	0,27	5	neutral	0,91	deleterious	0,52	neutral	-6	neutral	0,12	medium_impact	0,48	medium_impact	-0,39	medium_impact	0,63	0,55	0,8	20,04	18,16	N	0,46	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10772	10772	A	T	MI.16337	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	13	5	I	F	Atc/Ttc	-3,17	0	0	probably_damaging	0,93	neutral	0,1	neutral	1,32	neutral	-2,15	neutral	-2,21	medium_impact	3,02	neutral	0,65	neutral	0,51	deleterious	3,29	22,8	0,14	0,4	NA	NA	neutral	0,28	neutral	0,48	neutral	0,2	6	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,56	low_impact	-1,77	medium_impact	-0,33	medium_impact	1,86	0,49	0,8	20,04	18,16	N	0,47	N	0,95	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10772	10772	A	C	MI.16338	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	13	5	I	L	Atc/Ctc	-3,17	0	0	benign	0,39	neutral	1	neutral	1,67	neutral	0,36	neutral	-0,26	low_impact	1,17	neutral	0,67	neutral	0,86	neutral	-0,91	0,03	0,19	0,45	NA	NA	neutral	0,04	neutral	0,17	neutral	0,22	6	neutral	0,39	deleterious	0,81	neutral	-6	neutral	0,13	medium_impact	-0,54	high_impact	1,88	medium_impact	0,03	0,54	0,8	20,04	18,16	N	0,4	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10773	10773	T	C	MI.16339	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	14	5	I	T	aTc/aCc	-0,17	0	0	possibly_damaging	0,75	deleterious	0,03	neutral	1,31	neutral	-2,39	deleterious	-2,98	medium_impact	2,21	neutral	0,63	neutral	0,64	neutral	1,62	13,96	0,19	0,45	NA	NA	neutral	0,23	disease	0,58	neutral	0,36	3	neutral	0,98	neutral	0,14	deleterious	4	neutral	0,4	low_impact	-1,17	medium_impact	-0,64	medium_impact	1,06	0,19	0,8	20,04	18,16	N	0,42	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8455	8455	C	G	MI.1634	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	90	30	N	K	aaC/aaG	0,36	0	0	probably_damaging	0,92	neutral	0,36	neutral	1,09	deleterious	-3,2	neutral	-0,39	neutral_impact	0,54	neutral	0,98	neutral	0,94	deleterious	2,04	16,46	0,91446772	0,95	neutral	0,17	neutral	0,29	neutral	0,24	neutral	0,22	6	neutral	0,92	neutral	0,22	neutral	-2	deleterious	0,69	low_impact	-1,76	medium_impact	0,15	medium_impact	-0,64	0,85	0,9	NA	NA	N	0,51	P	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10773	10773	T	A	MI.16340	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	14	5	I	N	aTc/aAc	-0,17	0	0	probably_damaging	0,96	deleterious	0	neutral	1,26	deleterious	-3,98	deleterious	-4,46	medium_impact	3,02	neutral	0,63	neutral	0,38	deleterious	4,31	24	0,19	0,45	NA	NA	neutral	0,43	disease	0,62	neutral	0,43	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,69	low_impact	-2,01	low_impact	-1,48	medium_impact	1,86	0,21	0,8	20,04	18,16	N	0,38	N	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10773	10773	T	G	MI.16341	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	14	5	I	S	aTc/aGc	-0,17	0	0	probably_damaging	0,9	deleterious	0	neutral	1,29	neutral	-2,87	deleterious	-3,71	medium_impact	2,48	neutral	0,62	neutral	0,4	deleterious	2,61	20,2	0,16	0,45	NA	NA	neutral	0,42	disease	0,59	neutral	0,4	2	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,47	low_impact	-1,61	low_impact	-1,48	medium_impact	1,33	0,28	0,8	20,04	18,16	N	0,39	N	0,93	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10774	10774	C	G	MI.16342	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	15	5	I	M	atC/atG	7,44	0,96	0	probably_damaging	0,93	neutral	0,06	neutral	1,32	neutral	-2,16	neutral	-1,16	medium_impact	3,02	neutral	0,74	neutral	0,56	deleterious	2,95	22,1	0,21	0,45	NA	NA	neutral	0,19	neutral	0,28	neutral	0,23	5	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,57	low_impact	-1,77	medium_impact	-0,47	medium_impact	1,86	0,52	0,8	20,04	18,16	P	0,64	P	0,8	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10774	10774	C	A	MI.16343	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	15	5	I	M	atC/atA	7,44	0,96	0	probably_damaging	0,93	neutral	0,06	neutral	1,32	neutral	-2,16	neutral	-1,16	medium_impact	3,02	neutral	0,74	neutral	0,56	deleterious	3,46	23	0,21	0,45	NA	NA	neutral	0,19	neutral	0,28	neutral	0,23	5	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,57	low_impact	-1,77	medium_impact	-0,47	medium_impact	1,86	0,52	0,8	20,04	18,16	P	0,64	P	0,8	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10775	10775	G	A	MI.16344	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	16	6	V	I	Gtc/Atc	-3,63	0	0	benign	0	neutral	1	neutral	1,62	neutral	0,25	neutral	0,57	neutral_impact	-1,85	neutral	0,72	neutral	1	neutral	-1,1	0,01	0,44	0,55	NA	NA	neutral	0,01	neutral	0,14	neutral	0,19	6	neutral	0	deleterious	1	neutral	-6	neutral	0,08	high_impact	2,1	high_impact	1,88	low_impact	-2,96	0,59	0,8	19,17	13,21	N	0,41	N	0	polymorphism	1	0,01	rs879015842	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10775	10775	G	T	MI.16345	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	16	6	V	F	Gtc/Ttc	-3,63	0	0	benign	0	neutral	0,57	neutral	1,55	neutral	-0,31	neutral	-1,36	neutral_impact	-0,84	neutral	0,83	neutral	0,94	deleterious	0,74	9,11	0,18	0,45	NA	NA	neutral	0,22	neutral	0,23	neutral	0,17	7	neutral	0,42	deleterious	0,79	neutral	-6	neutral	0,18	high_impact	2,1	medium_impact	0,27	low_impact	-1,96	0,3	0,8	19,17	13,21	N	0,3	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10775	10775	G	C	MI.16346	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	16	6	V	L	Gtc/Ctc	-3,63	0	0	benign	0	neutral	0,55	neutral	1,81	neutral	1,23	neutral	-0,1	neutral_impact	-0,74	neutral	0,77	neutral	0,97	deleterious	0,17	4,37	0,32	0,5	NA	NA	neutral	0,08	neutral	0,18	neutral	0,23	5	neutral	0,45	deleterious	0,78	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	0,25	low_impact	-1,86	0,55	0,8	19,17	13,21	N	0,5	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10776	10776	T	C	MI.16347	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	17	6	V	A	gTc/gCc	-4,09	0	0	benign	0	deleterious	0	neutral	1,47	neutral	-1,36	neutral	-2,36	neutral_impact	0,4	neutral	0,76	neutral	0,96	neutral	1,57	13,71	0,25	0,45	NA	NA	neutral	0,11	neutral	0,49	neutral	0,21	6	deleterious	1	deleterious	0,5	neutral	-2	neutral	0,11	high_impact	2,1	low_impact	-1,48	medium_impact	-0,73	0,26	0,8	19,17	13,21	N	0,45	N	0,03	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10776	10776	T	A	MI.16348	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	17	6	V	D	gTc/gAc	-4,09	0	0	benign	0,27	deleterious	0	neutral	1,4	deleterious	-4,37	deleterious	-3,95	low_impact	1,1	neutral	0,68	neutral	0,47	deleterious	2,66	20,6	0,13	0,4	NA	NA	neutral	0,44	disease	0,64	neutral	0,41	2	deleterious	1	neutral	0,37	neutral	-2	neutral	0,34	medium_impact	-0,31	low_impact	-1,48	medium_impact	-0,04	0,12	0,8	19,17	13,21	N	0,36	N	0,39	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10776	10776	T	G	MI.16349	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	17	6	V	G	gTc/gGc	-4,09	0	0	benign	0,1	deleterious	0,03	neutral	1,41	deleterious	-3,25	deleterious	-4,4	low_impact	1,1	neutral	0,73	neutral	0,55	deleterious	1,88	15,5	0,18	0,45	NA	NA	neutral	0,24	disease	0,52	neutral	0,31	4	neutral	0,97	neutral	0,47	neutral	-2	neutral	0,17	medium_impact	0,18	medium_impact	-0,64	medium_impact	-0,04	0,17	0,8	19,17	13,21	N	0,43	N	0,37	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8455	8455	C	A	MI.1635	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	90	30	N	K	aaC/aaA	0,36	0	0	probably_damaging	0,92	neutral	0,36	neutral	1,09	deleterious	-3,2	neutral	-0,39	neutral_impact	0,54	neutral	0,98	neutral	0,94	deleterious	2,46	19,21	0,91446772	0,95	neutral	0,17	neutral	0,29	neutral	0,24	neutral	0,22	6	neutral	0,92	neutral	0,22	neutral	-2	deleterious	0,69	low_impact	-1,76	medium_impact	0,15	medium_impact	-0,64	0,85	0,9	NA	NA	N	0,53	P	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10778	10778	C	A	MI.16350	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	19	7	P	T	Cca/Aca	-7,78	0	0	probably_damaging	0,91	neutral	0,25	neutral	1,41	neutral	-1,9	deleterious	-5,45	medium_impact	2,58	neutral	0,76	neutral	0,54	deleterious	3,64	23,2	0,23	0,45	NA	NA	neutral	0,43	disease	0,63	neutral	0,39	2	neutral	0,93	neutral	0,17	deleterious	1	deleterious	0,77	low_impact	-1,66	medium_impact	-0,07	medium_impact	1,43	0,54	0,8	45,1	8,54	N	0,38	N	0,89	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10778	10778	C	T	MI.16351	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	19	7	P	S	Cca/Tca	-7,78	0	0	benign	0,42	neutral	0,29	neutral	1,42	neutral	-1,58	deleterious	-5,33	medium_impact	3,04	neutral	0,77	neutral	0,76	deleterious	3,85	23,4	0,25	0,45	NA	NA	neutral	0,43	neutral	0,45	neutral	0,19	6	neutral	0,66	neutral	0,44	neutral	-3	deleterious	0,78	medium_impact	-0,59	medium_impact	-0,02	medium_impact	1,88	0,33	0,8	45,1	8,54	N	0,42	N	0,71	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10778	10778	C	G	MI.16352	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	19	7	P	A	Cca/Gca	-7,78	0	0	possibly_damaging	0,86	neutral	0,38	neutral	1,48	neutral	-0,81	deleterious	-5,45	medium_impact	2,42	neutral	0,82	neutral	0,64	deleterious	3,04	22,3	0,25	0,45	NA	NA	neutral	0,32	neutral	0,48	neutral	0,17	7	neutral	0,86	neutral	0,26	NA	0	deleterious	0,76	low_impact	-1,46	medium_impact	0,08	medium_impact	1,27	0,63	0,8	45,1	8,54	N	0,37	N	0,77	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10779	10779	C	G	MI.16353	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	20	7	P	R	cCa/cGa	1,44	0,57	0	probably_damaging	0,97	neutral	0,2	neutral	1,37	deleterious	-3,1	deleterious	-6,25	medium_impact	3,38	neutral	0,67	neutral	0,42	deleterious	3,58	23,2	0,15	0,4	NA	NA	disease	0,73	disease	0,76	disease	0,75	5	neutral	0,98	neutral	0,12	deleterious	1	deleterious	0,84	low_impact	-2,14	medium_impact	-0,14	high_impact	2,22	0,36	0,8	45,1	8,54	N	0,39	N	0,58	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10779	10779	C	A	MI.16354	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	20	7	P	Q	cCa/cAa	1,44	0,57	0	probably_damaging	0,98	neutral	0,17	neutral	1,36	deleterious	-3,16	deleterious	-5,51	medium_impact	3,38	neutral	0,72	neutral	0,4	deleterious	4,1	23,7	0,18	0,45	NA	NA	disease	0,6	disease	0,68	disease	0,68	4	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,79	low_impact	-2,31	medium_impact	-0,18	high_impact	2,22	0,41	0,8	45,1	8,54	N	0,39	N	0,84	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10779	10779	C	T	MI.16355	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	20	7	P	L	cCa/cTa	1,44	0,57	0	probably_damaging	0,97	neutral	0,42	neutral	1,5	neutral	-0,64	deleterious	-6,99	medium_impact	3,38	neutral	0,71	neutral	0,43	deleterious	4,38	24,1	0,15	0,4	NA	NA	disease	0,64	disease	0,63	disease	0,67	3	neutral	0,97	neutral	0,23	deleterious	1	deleterious	0,8	low_impact	-2,14	medium_impact	0,12	high_impact	2,22	0,56	0,8	45,1	8,54	N	0,37	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10781	10781	A	T	MI.16356	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	22	8	T	S	Aca/Tca	-13,77	0	0	possibly_damaging	0,85	neutral	0,19	neutral	1,41	neutral	-1,48	deleterious	-2,69	low_impact	1,29	neutral	0,79	neutral	0,87	deleterious	2,06	16,62	0,21	0,45	NA	NA	neutral	0,3	neutral	0,39	neutral	0,16	7	neutral	0,91	neutral	0,17	neutral	-3	deleterious	0,75	low_impact	-1,43	medium_impact	-0,15	medium_impact	0,15	0,6	0,8	18,3	18,48	N	0,47	N	0,25	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10781	10781	A	C	MI.16357	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	22	8	T	P	Aca/Cca	-13,77	0	0	probably_damaging	0,98	deleterious	0,01	neutral	1,32	deleterious	-4,12	deleterious	-4,29	medium_impact	2,77	neutral	0,63	neutral	0,35	deleterious	3,31	22,9	0,1	0,4	NA	NA	disease	0,65	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,81	low_impact	-2,31	medium_impact	-0,92	medium_impact	1,61	0,44	0,8	18,3	18,48	N	0,35	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10781	10781	A	G	MI.16358	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	22	8	T	A	Aca/Gca	-13,77	0	0	possibly_damaging	0,74	deleterious	0,04	neutral	1,39	neutral	-1,76	deleterious	-3,51	medium_impact	3,12	neutral	0,8	neutral	0,55	deleterious	3,29	22,8	0,24	0,45	NA	NA	neutral	0,37	disease	0,63	neutral	0,39	2	neutral	0,97	neutral	0,15	deleterious	4	deleterious	0,75	low_impact	-1,14	medium_impact	-0,57	medium_impact	1,96	0,2	0,8	18,3	18,48	N	0,44	N	0,75	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10782	10782	C	A	MI.16359	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	23	8	T	K	aCa/aAa	3,75	0,99	0	probably_damaging	0,94	deleterious	0,02	neutral	1,33	deleterious	-3,36	deleterious	-4,25	medium_impact	3,12	neutral	0,71	neutral	0,38	deleterious	4,27	24	0,12	0,4	NA	NA	disease	0,7	disease	0,74	disease	0,74	5	deleterious	0,99	neutral	0,04	deleterious	5	deleterious	0,81	low_impact	-1,84	medium_impact	-0,75	medium_impact	1,96	0,37	0,8	18,3	18,48	P	0,54	P	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8456	8456	A	C	MI.1636	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	91	31	T	P	Aca/Cca	-9,36	0	0	benign	0,07	neutral	0,21	neutral	0,53	deleterious	-6,41	neutral	-1,96	low_impact	1,73	neutral	0,99	neutral	0,41	deleterious	0,12	3,82	0,13551864	0,85	neutral	0,43	neutral	0,44	neutral	0,32	neutral	0,21	6	neutral	0,77	deleterious	0,57	neutral	-6	neutral	0,22	medium_impact	0,31	medium_impact	-0,03	medium_impact	0,39	0,53	0,85	4,41	7,27	N	0,52	P	0,3	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10782	10782	C	T	MI.16360	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	23	8	T	M	aCa/aTa	3,75	0,99	0	possibly_damaging	0,52	neutral	0,3	neutral	1,4	neutral	-1,58	deleterious	-4,26	medium_impact	2,43	neutral	0,83	neutral	0,6	deleterious	3,69	23,3	0,15	0,45	NA	NA	neutral	0,49	disease	0,55	neutral	0,41	2	neutral	0,68	neutral	0,39	NA	0	deleterious	0,75	medium_impact	-0,75	medium_impact	0	medium_impact	1,28	0,39	0,8	18,3	18,48	P	0,6	P	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10784	10784	A	C	MI.16361	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	25	9	I	L	Att/Ctt	-5,7	0	0	benign	0,03	neutral	1	neutral	1,64	neutral	-0,01	neutral	-0,53	neutral_impact	0,56	neutral	0,76	neutral	0,97	neutral	-0,27	0,77	0,18	0,45	NA	NA	neutral	0,13	neutral	0,19	neutral	0,24	5	neutral	0,03	deleterious	0,99	neutral	-6	neutral	0,1	medium_impact	0,7	high_impact	1,88	medium_impact	-0,57	0,51	0,8	21,35	11,49	N	0,38	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10784	10784	A	G	MI.16362	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	25	9	I	V	Att/Gtt	-5,7	0	0	benign	0,01	neutral	0,17	neutral	1,52	neutral	0,03	neutral	-0,49	medium_impact	2,1	neutral	0,83	neutral	0,93	neutral	-0,23	0,96	0,2	0,45	NA	NA	neutral	0,11	neutral	0,29	neutral	0,26	5	neutral	0,83	deleterious	0,58	neutral	-3	neutral	0,07	medium_impact	1,16	medium_impact	-0,18	medium_impact	0,95	0,34	0,8	21,35	11,49	N	0,49	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10784	10784	A	T	MI.16363	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	25	9	I	F	Att/Ttt	-5,7	0	0	benign	0,38	neutral	0,17	neutral	1,43	neutral	-2,23	neutral	-1,89	low_impact	1,84	neutral	0,79	neutral	0,9	neutral	1,01	10,73	0,14	0,4	NA	NA	neutral	0,29	neutral	0,3	neutral	0,21	6	neutral	0,8	neutral	0,4	neutral	-6	neutral	0,43	medium_impact	-0,52	medium_impact	-0,18	medium_impact	0,69	0,48	0,8	21,35	11,49	N	0,46	N	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10785	10785	T	C	MI.16364	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	26	9	I	T	aTt/aCt	-2,24	0	0	benign	0,01	neutral	0,13	neutral	1,4	neutral	-2,38	neutral	-2,49	low_impact	1,13	neutral	0,79	neutral	0,98	deleterious	0,1	3,62	0,13	0,4	NA	NA	neutral	0,19	neutral	0,35	neutral	0,21	6	neutral	0,87	deleterious	0,56	neutral	-6	neutral	0,11	medium_impact	1,16	medium_impact	-0,26	medium_impact	-0,01	0,21	0,8	21,35	11,49	N	0,48	N	0,37	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10785	10785	T	A	MI.16365	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	26	9	I	N	aTt/aAt	-2,24	0	0	benign	0,38	deleterious	0,01	neutral	1,34	deleterious	-3,82	deleterious	-4,01	medium_impact	2,65	neutral	0,77	neutral	0,52	deleterious	2,56	19,88	0,12	0,4	NA	NA	neutral	0,49	disease	0,6	disease	0,68	4	deleterious	0,99	neutral	0,32	deleterious	1	neutral	0,43	medium_impact	-0,52	medium_impact	-0,92	medium_impact	1,5	0,12	0,8	21,35	11,49	N	0,39	N	0,89	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10785	10785	T	G	MI.16366	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	26	9	I	S	aTt/aGt	-2,24	0	0	benign	0,18	deleterious	0,02	neutral	1,38	neutral	-2,87	deleterious	-3,25	medium_impact	2,1	neutral	0,76	neutral	0,66	deleterious	2,13	17,05	0,06	0,35	NA	NA	neutral	0,47	neutral	0,5	neutral	0,33	3	neutral	0,98	neutral	0,42	deleterious	1	neutral	0,24	medium_impact	-0,1	medium_impact	-0,75	medium_impact	0,95	0,19	0,8	21,35	11,49	N	0,42	N	0,78	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10786	10786	T	A	MI.16367	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	27	9	I	M	atT/atA	0,75	0	0	benign	0,03	neutral	0,16	neutral	1,44	neutral	-2,32	neutral	-1,04	neutral_impact	0,68	neutral	0,83	neutral	0,99	neutral	1,71	14,44	0,21	0,45	NA	NA	neutral	0,16	neutral	0,23	neutral	0,24	5	neutral	0,83	deleterious	0,57	neutral	-6	deleterious	0,44	medium_impact	0,7	medium_impact	-0,2	medium_impact	-0,45	0,52	0,8	21,35	11,49	P	0,53	P	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10786	10786	T	G	MI.16368	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	27	9	I	M	atT/atG	0,75	0	0	benign	0,03	neutral	0,16	neutral	1,44	neutral	-2,32	neutral	-1,04	neutral_impact	0,68	neutral	0,83	neutral	0,99	neutral	1,38	12,67	0,21	0,45	NA	NA	neutral	0,16	neutral	0,23	neutral	0,24	5	neutral	0,83	deleterious	0,57	neutral	-6	deleterious	0,44	medium_impact	0,7	medium_impact	-0,2	medium_impact	-0,45	0,52	0,8	21,35	11,49	P	0,53	P	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10787	10787	A	G	MI.16369	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	28	10	M	V	Ata/Gta	-14,24	0	0	benign	0,22	neutral	0,05	neutral	1,49	neutral	-0,85	deleterious	-2,88	medium_impact	3,37	neutral	0,63	neutral	0,55	deleterious	2,49	19,42	0,17	0,45	NA	NA	disease	0,65	disease	0,67	disease	0,68	4	neutral	0,94	neutral	0,42	neutral	-3	deleterious	0,71	medium_impact	-0,2	medium_impact	-0,52	high_impact	2,21	0,38	0,8	45,53	8,91	N	0,47	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8456	8456	A	G	MI.1637	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	91	31	T	A	Aca/Gca	-9,36	0	0	benign	0,01	neutral	0,5	neutral	0,56	deleterious	-5,07	neutral	-0,88	low_impact	1,73	neutral	1	neutral	0,74	neutral	-0,5	0,22	0,8102732	0,9	neutral	0,2	neutral	0,13	neutral	0,33	neutral	0,1	8	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,15	medium_impact	1,14	medium_impact	0,29	medium_impact	0,39	0,38	0,85	4,41	7,27	N	0,43	N	0,3	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10787	10787	A	C	MI.16370	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	28	10	M	L	Ata/Cta	-14,24	0	0	benign	0,16	neutral	0,17	neutral	1,55	neutral	-0,27	neutral	-2,09	medium_impact	2,47	neutral	0,8	neutral	0,75	deleterious	2,94	22	0,17	0,45	NA	NA	disease	0,56	neutral	0,41	neutral	0,45	1	neutral	0,8	deleterious	0,51	neutral	-3	deleterious	0,62	medium_impact	-0,04	medium_impact	-0,18	medium_impact	1,32	0,36	0,8	45,53	8,91	N	0,4	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10787	10787	A	T	MI.16371	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	28	10	M	L	Ata/Tta	-14,24	0	0	benign	0,16	neutral	0,17	neutral	1,55	neutral	-0,27	neutral	-2,09	medium_impact	2,47	neutral	0,8	neutral	0,75	deleterious	3,01	22,3	0,17	0,45	NA	NA	disease	0,56	neutral	0,41	neutral	0,45	1	neutral	0,8	deleterious	0,51	neutral	-3	deleterious	0,62	medium_impact	-0,04	medium_impact	-0,18	medium_impact	1,32	0,36	0,8	45,53	8,91	N	0,41	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10788	10788	T	C	MI.16372	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	29	10	M	T	aTa/aCa	1,91	0,77	0	possibly_damaging	0,71	deleterious	0,04	neutral	1,45	neutral	-1,43	deleterious	-4,36	medium_impact	2,47	neutral	0,8	neutral	0,64	deleterious	2,63	20,4	0,14	0,4	NA	NA	disease	0,62	disease	0,51	neutral	0,46	1	neutral	0,97	neutral	0,17	deleterious	4	deleterious	0,79	low_impact	-1,08	medium_impact	-0,57	medium_impact	1,32	0,1	0,8	45,53	8,91	N	0,37	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10788	10788	T	A	MI.16373	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	29	10	M	K	aTa/aAa	1,91	0,77	0	possibly_damaging	0,86	deleterious	0,01	neutral	1,39	neutral	-2,85	deleterious	-4,39	medium_impact	3,37	neutral	0,64	neutral	0,42	deleterious	3,66	23,2	0,05	0,35	NA	NA	disease	0,81	disease	0,73	disease	0,75	5	deleterious	0,99	neutral	0,08	deleterious	4	deleterious	0,84	low_impact	-1,46	medium_impact	-0,92	high_impact	2,21	0,19	0,8	45,53	8,91	N	0,39	N	1	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10789	10789	A	T	MI.16374	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	30	10	M	I	atA/atT	3,75	0,86	0	benign	0,04	deleterious	0,03	neutral	1,45	neutral	-1,29	deleterious	-2,86	medium_impact	2,82	neutral	0,67	neutral	0,59	deleterious	3,16	22,6	0,2	0,45	NA	NA	disease	0,65	disease	0,58	disease	0,59	2	neutral	0,97	deleterious	0,5	deleterious	1	deleterious	0,75	medium_impact	0,58	medium_impact	-0,64	medium_impact	1,66	0,44	0,8	45,53	8,91	N	0,46	N	0,95	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10789	10789	A	C	MI.16375	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	30	10	M	I	atA/atC	3,75	0,86	0	benign	0,04	deleterious	0,03	neutral	1,45	neutral	-1,29	deleterious	-2,86	medium_impact	2,82	neutral	0,67	neutral	0,59	deleterious	3,14	22,6	0,2	0,45	NA	NA	disease	0,65	disease	0,58	disease	0,59	2	neutral	0,97	deleterious	0,5	deleterious	1	deleterious	0,75	medium_impact	0,58	medium_impact	-0,64	medium_impact	1,66	0,44	0,8	45,53	8,91	N	0,45	N	0,95	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10790	10790	T	A	MI.16376	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	31	11	L	M	Tta/Ata	0,06	0,02	0,02	possibly_damaging	0,76	neutral	0,29	neutral	1,03	neutral	-2,55	neutral	-1,37	medium_impact	1,97	neutral	0,75	neutral	0,33	deleterious	2,28	18,01	0,17	0,45	NA	NA	neutral	0,26	neutral	0,27	neutral	0,19	6	neutral	0,82	neutral	0,27	NA	0	deleterious	0,75	low_impact	-1,19	medium_impact	-0,02	medium_impact	0,82	0,37	0,8	13,73	9,93	N	0,43	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10790	10790	T	G	MI.16377	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	31	11	L	V	Tta/Gta	0,06	0,02	0,02	possibly_damaging	0,9	neutral	0,05	neutral	1,02	neutral	-2,64	neutral	-2,16	medium_impact	3,35	neutral	0,67	damaging	0,14	deleterious	3,2	22,7	0,19	0,45	NA	NA	neutral	0,41	disease	0,63	neutral	0,38	2	deleterious	0,98	neutral	0,08	NA	0	deleterious	0,8	low_impact	-1,61	medium_impact	-0,52	high_impact	2,19	0,53	0,8	13,73	9,93	N	0,41	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10791	10791	T	G	MI.16378	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	32	11	L	W	tTa/tGa	-0,17	0,02	0	probably_damaging	1	deleterious	0	neutral	0,89	deleterious	-6,65	deleterious	-4,38	medium_impact	3,35	damaging	0,59	damaging	0,14	deleterious	3,52	23,1	0,07	0,35	NA	NA	disease	0,62	disease	0,66	disease	0,68	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,19	0,16	0,8	13,73	9,93	N	0,33	N	0,98	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10791	10791	T	C	MI.16379	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	32	11	L	S	tTa/tCa	-0,17	0,02	0	probably_damaging	0,98	deleterious	0,03	neutral	0,94	deleterious	-4,04	deleterious	-4,36	medium_impact	2,8	neutral	0,63	damaging	0,14	deleterious	3,57	23,1	0,09	0,35	NA	NA	disease	0,6	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,83	low_impact	-2,31	medium_impact	-0,64	medium_impact	1,64	0,24	0,8	13,73	9,93	N	0,31	N	0,95	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8456	8456	A	T	MI.1638	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	91	31	T	S	Aca/Tca	-9,36	0	0	benign	0	neutral	0,41	neutral	0,7	neutral	-2,93	neutral	0,01	neutral_impact	0,42	neutral	1	neutral	0,93	neutral	-0,54	0,17	0,66698427	0,85	neutral	0,19	neutral	0,1	neutral	0,32	neutral	0,04	9	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,13	high_impact	2,09	medium_impact	0,2	medium_impact	-0,74	0,59	0,85	4,41	7,27	N	0,48	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10792	10792	A	C	MI.16380	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	33	11	L	F	ttA/ttC	7,44	0,96	0	probably_damaging	0,98	deleterious	0	neutral	0,96	deleterious	-3,6	deleterious	-2,91	medium_impact	3	neutral	0,63	damaging	0,14	deleterious	3,23	22,8	0,16	0,45	NA	NA	neutral	0,47	disease	0,53	neutral	0,4	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-2,31	low_impact	-1,48	medium_impact	1,84	0,52	0,8	13,73	9,93	P	0,56	P	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10792	10792	A	T	MI.16381	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	33	11	L	F	ttA/ttT	7,44	0,96	0	probably_damaging	0,98	deleterious	0	neutral	0,96	deleterious	-3,6	deleterious	-2,91	medium_impact	3	neutral	0,63	damaging	0,14	deleterious	3,37	22,9	0,16	0,45	NA	NA	neutral	0,47	disease	0,53	neutral	0,4	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-2,31	low_impact	-1,48	medium_impact	1,84	0,52	0,8	13,73	9,93	P	0,57	P	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10793	10793	C	A	MI.16382	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	34	12	L	M	Cta/Ata	-9,39	0	0	benign	0,4	neutral	0,25	neutral	1,48	neutral	-1	neutral	-0,61	low_impact	0,88	neutral	0,83	neutral	0,99	deleterious	2,16	17,25	0,17	0,45	NA	NA	neutral	0,2	neutral	0,18	neutral	0,22	6	neutral	0,71	neutral	0,43	neutral	-6	deleterious	0,71	medium_impact	-0,55	medium_impact	-0,07	medium_impact	-0,26	0,47	0,8	23,97	36,9	N	0,55	P	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10793	10793	C	G	MI.16383	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	34	12	L	V	Cta/Gta	-9,39	0	0	benign	0,4	neutral	0,29	neutral	1,51	neutral	-0,61	neutral	-0,58	low_impact	1,82	neutral	0,8	neutral	0,96	deleterious	1,95	15,87	0,16	0,45	NA	NA	neutral	0,25	neutral	0,21	neutral	0,2	6	neutral	0,66	neutral	0,45	neutral	-6	deleterious	0,71	medium_impact	-0,55	medium_impact	-0,02	medium_impact	0,68	0,49	0,8	23,97	36,9	N	0,47	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10794	10794	T	C	MI.16384	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	35	12	L	P	cTa/cCa	-2,48	0	0	probably_damaging	0,96	deleterious	0	neutral	1,38	deleterious	-3,77	deleterious	-3,87	medium_impact	2,62	damaging	0,56	neutral	0,39	deleterious	3,72	23,3	0,06	0,35	NA	NA	disease	0,78	disease	0,65	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,83	low_impact	-2,01	low_impact	-1,48	medium_impact	1,47	0,23	0,8	23,97	36,9	N	0,33	N	0,93	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10794	10794	T	G	MI.16385	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	35	12	L	R	cTa/cGa	-2,48	0	0	probably_damaging	0,93	deleterious	0	neutral	1,39	deleterious	-3,18	deleterious	-3,45	medium_impact	2,27	neutral	0,65	neutral	0,47	deleterious	3,93	23,5	0,05	0,35	NA	NA	disease	0,77	disease	0,65	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,83	low_impact	-1,77	low_impact	-1,48	medium_impact	1,12	0,17	0,8	23,97	36,9	N	0,32	N	0,93	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10794	10794	T	A	MI.16386	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	35	12	L	Q	cTa/cAa	-2,48	0	0	probably_damaging	0,93	deleterious	0	neutral	1,39	deleterious	-3,34	deleterious	-3,38	medium_impact	2,62	neutral	0,7	neutral	0,54	deleterious	4	23,6	0,07	0,35	NA	NA	disease	0,57	disease	0,51	disease	0,57	1	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,75	low_impact	-1,77	low_impact	-1,48	medium_impact	1,47	0,21	0,8	23,97	36,9	N	0,41	N	0,89	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10796	10796	C	T	MI.16387	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	37	13	P	S	Cca/Tca	-7,32	0	0	probably_damaging	1	deleterious	0,01	neutral	1,33	neutral	-2,19	deleterious	-5,8	medium_impact	3,46	neutral	0,62	damaging	0,17	deleterious	3,66	23,2	0,18	0,45	NA	NA	disease	0,68	disease	0,62	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,82	low_impact	-3,54	medium_impact	-0,92	high_impact	2,3	0,27	0,8	45,97	8,92	N	0,31	N	0,71	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10796	10796	C	G	MI.16388	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	37	13	P	A	Cca/Gca	-7,32	0	0	probably_damaging	1	deleterious	0,03	neutral	1,33	neutral	-2,14	deleterious	-5,78	medium_impact	3,12	neutral	0,64	damaging	0,2	deleterious	2,83	21,5	0,19	0,45	NA	NA	disease	0,53	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,78	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,96	0,64	0,8	45,97	8,92	N	0,31	N	0,77	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10796	10796	C	A	MI.16389	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	37	13	P	T	Cca/Aca	-7,32	0	0	probably_damaging	1	neutral	0,06	neutral	1,32	neutral	-2,27	deleterious	-5,78	medium_impact	3,46	neutral	0,65	damaging	0,14	deleterious	3,45	23	0,17	0,45	NA	NA	disease	0,66	disease	0,57	disease	0,66	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,47	high_impact	2,3	0,58	0,8	45,97	8,92	N	0,33	N	0,89	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8457	8457	C	A	MI.1639	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	92	31	T	K	aCa/aAa	-0,8	0	0	benign	0,02	neutral	0,3	neutral	0,54	deleterious	-5,78	neutral	-1,09	low_impact	1,73	neutral	0,99	neutral	0,57	neutral	0,98	10,53	0,35296026	0,85	neutral	0,18	neutral	0,34	neutral	0,39	neutral	0,16	7	neutral	0,69	deleterious	0,64	neutral	-6	neutral	0,17	medium_impact	0,85	medium_impact	0,08	medium_impact	0,39	0,58	0,85	4,41	7,27	N	0,53	P	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10797	10797	C	G	MI.16390	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	38	13	P	R	cCa/cGa	4,21	0,98	0	probably_damaging	1	deleterious	0,01	neutral	1,28	deleterious	-3,64	deleterious	-6,53	medium_impact	3,46	neutral	0,64	damaging	0,15	deleterious	3,29	22,8	0,1	0,4	NA	NA	disease	0,83	disease	0,75	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,87	low_impact	-3,54	medium_impact	-0,92	high_impact	2,3	0,43	0,8	45,97	8,92	N	0,52	P	0,58	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10797	10797	C	T	MI.16391	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	38	13	P	L	cCa/cTa	4,21	0,98	0	probably_damaging	1	neutral	0,47	neutral	1,46	neutral	-0,71	deleterious	-7,16	medium_impact	2,91	neutral	0,69	damaging	0,2	deleterious	4,06	23,7	0,12	0,4	NA	NA	disease	0,75	neutral	0,44	disease	0,51	0	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	0,17	medium_impact	1,75	0,68	0,85	45,97	8,92	N	0,51	P	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10797	10797	C	A	MI.16392	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	38	13	P	Q	cCa/cAa	4,21	0,98	0	probably_damaging	1	deleterious	0,02	neutral	1,28	deleterious	-3,51	deleterious	-5,8	medium_impact	3,46	neutral	0,64	damaging	0,14	deleterious	3,88	23,5	0,12	0,4	NA	NA	disease	0,78	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-3,54	medium_impact	-0,75	high_impact	2,3	0,46	0,8	45,97	8,92	P	0,53	P	0,84	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10799	10799	C	A	MI.16393	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	40	14	L	M	Ctg/Atg	-13,08	0	0	benign	0,08	neutral	0,33	neutral	1,42	neutral	-1,27	neutral	-0,49	low_impact	1,12	neutral	0,82	neutral	0,96	deleterious	2,23	17,69	0,19	0,45	NA	NA	neutral	0,18	neutral	0,22	neutral	0,23	5	neutral	0,63	deleterious	0,63	neutral	-6	deleterious	0,72	medium_impact	0,28	medium_impact	0,03	medium_impact	-0,02	0,51	0,8	25,05	19,07	N	0,43	N	0,16	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10799	10799	C	G	MI.16394	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	40	14	L	V	Ctg/Gtg	-13,08	0	0	benign	0,04	neutral	0,57	neutral	1,44	neutral	-1,05	neutral	-0,82	medium_impact	2,36	neutral	0,74	neutral	0,86	neutral	1,25	12,02	0,18	0,45	NA	NA	neutral	0,36	neutral	0,26	neutral	0,2	6	neutral	0,38	deleterious	0,77	neutral	-3	deleterious	0,74	medium_impact	0,58	medium_impact	0,27	medium_impact	1,21	0,49	0,8	25,05	19,07	N	0,42	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10800	10800	T	G	MI.16395	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	41	14	L	R	cTg/cGg	-1,09	0	0	possibly_damaging	0,75	neutral	0,15	neutral	1,31	deleterious	-3,58	deleterious	-2,73	medium_impact	2,71	neutral	0,61	neutral	0,41	deleterious	3,88	23,5	0,06	0,35	NA	NA	disease	0,83	disease	0,71	disease	0,79	6	neutral	0,89	neutral	0,2	NA	0	deleterious	0,85	low_impact	-1,17	medium_impact	-0,22	medium_impact	1,56	0,2	0,8	25,05	19,07	N	0,35	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10800	10800	T	C	MI.16396	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	41	14	L	P	cTg/cCg	-1,09	0	0	possibly_damaging	0,87	neutral	0,11	neutral	1,31	deleterious	-4,21	deleterious	-3,15	medium_impact	2,71	damaging	0,56	neutral	0,33	deleterious	2,63	20,4	0,07	0,35	NA	NA	disease	0,81	disease	0,65	disease	0,77	5	neutral	0,95	neutral	0,12	NA	0	deleterious	0,84	low_impact	-1,49	medium_impact	-0,31	medium_impact	1,56	0,18	0,8	25,05	19,07	N	0,33	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10800	10800	T	A	MI.16397	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	41	14	L	Q	cTg/cAg	-1,09	0	0	possibly_damaging	0,83	neutral	0,15	neutral	1,31	deleterious	-3,73	deleterious	-2,61	medium_impact	2,71	neutral	0,67	neutral	0,47	deleterious	3,95	23,6	0,08	0,35	NA	NA	disease	0,6	neutral	0,5	disease	0,51	0	neutral	0,92	neutral	0,16	NA	0	deleterious	0,76	low_impact	-1,37	medium_impact	-0,22	medium_impact	1,56	0,22	0,8	25,05	19,07	N	0,44	N	0,85	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10802	10802	A	G	MI.16398	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	43	15	T	A	Aca/Gca	-7,78	0	0	possibly_damaging	0,64	neutral	0,82	neutral	1,55	neutral	-0,37	neutral	-2,1	low_impact	1,46	neutral	0,78	neutral	0,88	deleterious	2,02	16,33	0,19	0,45	NA	NA	neutral	0,19	neutral	0,29	neutral	0,21	6	neutral	0,57	deleterious	0,59	neutral	-3	deleterious	0,7	medium_impact	-0,95	medium_impact	0,57	medium_impact	0,32	0,48	0,8	17,65	14,93	N	0,27	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10802	10802	A	C	MI.16399	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	43	15	T	P	Aca/Cca	-7,78	0	0	benign	0,12	neutral	0,13	neutral	1,44	neutral	-2,38	deleterious	-3,25	medium_impact	2,69	neutral	0,73	neutral	0,4	deleterious	3,26	22,8	0,07	0,35	NA	NA	disease	0,77	disease	0,7	disease	0,76	5	neutral	0,85	deleterious	0,51	neutral	-3	deleterious	0,8	medium_impact	0,1	medium_impact	-0,26	medium_impact	1,54	0,38	0,8	17,65	14,93	N	0,36	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8603	8603	T	G	MI.164	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	77	26	F	C	tTt/tGt	-0,33	0	0	possibly_damaging	0,78	deleterious	0	neutral	4,23	deleterious	-3,24	deleterious	-4,5	medium_impact	2,19	neutral	0,76	neutral	0,48	deleterious	3,77	23,4	0,27	0,65	disease	0,85	disease	0,63	disease	0,53	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	4	deleterious	0,69	low_impact	-1,28	low_impact	-1,4	medium_impact	0,78	0,28	0,9	15,49	8,03	N	0,31	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8457	8457	C	T	MI.1640	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	92	31	T	M	aCa/aTa	-0,8	0	0	benign	0,36	neutral	0,22	neutral	0,53	deleterious	-6,26	neutral	-0,28	neutral_impact	0,42	neutral	1	neutral	0,67	deleterious	0,82	9,61	0,44957237	0,85	neutral	0,42	neutral	0,12	neutral	0,21	neutral	0,08	9	neutral	0,74	neutral	0,43	neutral	-6	neutral	0,3	medium_impact	-0,52	medium_impact	-0,02	medium_impact	-0,74	0,61	0,85	4,41	7,27	N	0,55	P	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10802	10802	A	T	MI.16400	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	43	15	T	S	Aca/Tca	-7,78	0	0	possibly_damaging	0,8	neutral	0,43	neutral	1,55	neutral	-0,3	neutral	-2,02	medium_impact	2,35	neutral	0,72	neutral	0,76	deleterious	1,94	15,85	0,23	0,45	NA	NA	neutral	0,36	neutral	0,28	neutral	0,2	6	neutral	0,8	neutral	0,32	NA	0	deleterious	0,72	low_impact	-1,28	medium_impact	0,13	medium_impact	1,2	0,68	0,85	17,65	14,93	N	0,47	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10803	10803	C	A	MI.16401	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	44	15	T	K	aCa/aAa	0,29	0	0	possibly_damaging	0,88	neutral	0,07	neutral	1,45	neutral	-1,91	deleterious	-3,21	medium_impact	3,04	neutral	0,72	neutral	0,38	deleterious	4,2	23,9	0,08	0,35	NA	NA	disease	0,71	disease	0,69	disease	0,74	5	neutral	0,97	neutral	0,1	NA	0	deleterious	0,78	low_impact	-1,53	medium_impact	-0,43	medium_impact	1,88	0,44	0,8	17,65	14,93	N	0,42	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10803	10803	C	T	MI.16402	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	44	15	T	M	aCa/aTa	0,29	0	0	possibly_damaging	0,52	neutral	0,12	neutral	1,46	neutral	-1,68	neutral	-2,27	medium_impact	2,15	neutral	0,78	neutral	0,81	deleterious	3,78	23,4	0,08	0,35	NA	NA	neutral	0,5	neutral	0,49	neutral	0,48	0	neutral	0,87	neutral	0,3	NA	0	deleterious	0,72	medium_impact	-0,75	medium_impact	-0,28	medium_impact	1	0,59	0,8	17,65	14,93	N	0,41	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10805	10805	T	G	MI.16403	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	46	16	W	G	Tga/Gga	-4,78	0	0	probably_damaging	1	deleterious	0,02	neutral	1,5	neutral	-1,97	deleterious	-9,15	medium_impact	3	neutral	0,7	damaging	0,18	deleterious	3,72	23,3	0,09	0,35	NA	NA	disease	0,68	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,84	0,24	0,8	39,87	8,23	N	0,33	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10805	10805	T	C	MI.16404	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	46	16	W	R	Tga/Cga	-4,78	0	0	probably_damaging	1	deleterious	0,02	neutral	1,5	neutral	-2,1	deleterious	-9,86	medium_impact	3,35	neutral	0,72	damaging	0,13	deleterious	3,34	22,9	0,07	0,35	NA	NA	disease	0,82	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,85	low_impact	-3,54	medium_impact	-0,75	high_impact	2,19	0,18	0,8	39,87	8,23	N	0,4	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10806	10806	G	C	MI.16405	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	47	16	W	S	tGa/tCa	1,68	0,78	0	probably_damaging	1	deleterious	0,04	neutral	1,55	neutral	-0,56	deleterious	-9,71	medium_impact	3,35	neutral	0,72	damaging	0,2	deleterious	3,76	23,3	0,09	0,35	NA	NA	disease	0,71	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-3,54	medium_impact	-0,57	high_impact	2,19	0,28	0,8	39,87	8,23	N	0,41	N	0,93	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10806	10806	G	T	MI.16406	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	47	16	W	L	tGa/tTa	1,68	0,78	0	probably_damaging	1	neutral	0,55	neutral	1,74	neutral	1,29	deleterious	-9,2	medium_impact	2,15	neutral	0,73	neutral	0,32	deleterious	4,01	23,6	0,1	0,4	NA	NA	neutral	0,45	neutral	0,48	neutral	0,22	6	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,25	medium_impact	1	0,23	0,8	39,87	8,23	N	0,34	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10807	10807	A	T	MI.16407	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	48	16	W	C	tgA/tgT	2,37	0,8	0	probably_damaging	1	deleterious	0,01	neutral	1,51	neutral	-1,59	deleterious	-9,17	medium_impact	2,65	neutral	0,76	damaging	0,17	deleterious	3,92	23,5	0,09	0,35	NA	NA	disease	0,73	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,5	0,3	0,8	39,87	8,23	N	0,36	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10807	10807	A	C	MI.16408	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	48	16	W	C	tgA/tgC	2,37	0,8	0	probably_damaging	1	deleterious	0,01	neutral	1,51	neutral	-1,59	deleterious	-9,17	medium_impact	2,65	neutral	0,76	damaging	0,17	deleterious	3,78	23,4	0,09	0,35	NA	NA	disease	0,73	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,5	0,3	0,8	39,87	8,23	N	0,35	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10808	10808	C	T	MI.16409	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	49	17	L	F	Ctt/Ttt	0,29	0,01	0	benign	0,04	neutral	0,17	neutral	1,38	neutral	-1,64	neutral	-1,17	low_impact	1,59	neutral	0,77	neutral	0,98	deleterious	2,43	19,04	0,19	0,45	NA	NA	neutral	0,37	neutral	0,3	neutral	0,2	6	neutral	0,82	deleterious	0,57	neutral	-6	deleterious	0,73	medium_impact	0,58	medium_impact	-0,18	medium_impact	0,45	0,52	0,8	20,7	14,56	N	0,45	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8459	8459	A	C	MI.1641	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	94	32	N	H	Aac/Cac	-2,65	0	0	probably_damaging	1	neutral	0,54	neutral	1,5	neutral	-2,24	neutral	-1,63	neutral_impact	0,7	neutral	1	neutral	0,94	neutral	0,97	10,47	0,73321515	0,85	neutral	0,4	neutral	0,13	disease	0,61	neutral	0,07	9	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	0,33	medium_impact	-0,5	0,49	0,85	13,24	7,92	N	0,36	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10808	10808	C	G	MI.16410	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	49	17	L	V	Ctt/Gtt	0,29	0,01	0	benign	0,32	neutral	0,1	neutral	1,43	neutral	-1,08	neutral	-1,59	medium_impact	2,61	neutral	0,69	neutral	0,66	deleterious	3,23	22,8	0,3	0,45	NA	NA	neutral	0,44	neutral	0,31	neutral	0,25	5	neutral	0,88	neutral	0,39	neutral	-3	deleterious	0,73	medium_impact	-0,41	medium_impact	-0,33	medium_impact	1,46	0,5	0,8	20,7	14,56	N	0,48	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10808	10808	C	A	MI.16411	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	49	17	L	I	Ctt/Att	0,29	0,01	0	benign	0,06	neutral	0,14	neutral	1,45	neutral	-0,89	neutral	-1	medium_impact	2,12	neutral	0,7	neutral	0,73	deleterious	3,87	23,5	0,27	0,45	NA	NA	neutral	0,46	neutral	0,26	neutral	0,27	5	neutral	0,85	deleterious	0,54	neutral	-3	deleterious	0,74	medium_impact	0,41	medium_impact	-0,24	medium_impact	0,97	0,49	0,8	20,7	14,56	N	0,5	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10809	10809	T	A	MI.16412	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	50	17	L	H	cTt/cAt	-3,86	0	0	benign	0,13	deleterious	0,01	neutral	1,28	deleterious	-4,2	deleterious	-3,58	medium_impact	3,15	neutral	0,64	neutral	0,51	deleterious	4,15	23,8	0,08	0,35	NA	NA	disease	0,7	disease	0,7	disease	0,69	4	deleterious	0,99	neutral	0,44	deleterious	1	deleterious	0,78	medium_impact	0,06	medium_impact	-0,92	medium_impact	1,99	0,15	0,8	20,7	14,56	N	0,38	N	0,76	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10809	10809	T	G	MI.16413	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	50	17	L	R	cTt/cGt	-3,86	0	0	possibly_damaging	0,87	deleterious	0,01	neutral	1,29	deleterious	-3,59	deleterious	-3,52	medium_impact	3,15	damaging	0,59	neutral	0,37	deleterious	4,04	23,7	0,05	0,35	NA	NA	disease	0,84	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,07	deleterious	4	deleterious	0,85	low_impact	-1,49	medium_impact	-0,92	medium_impact	1,99	0,17	0,8	20,7	14,56	N	0,35	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10809	10809	T	C	MI.16414	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	50	17	L	P	cTt/cCt	-3,86	0	0	probably_damaging	0,95	deleterious	0	neutral	1,28	deleterious	-4,27	deleterious	-4,21	medium_impact	3,15	damaging	0,57	neutral	0,32	deleterious	3,8	23,4	0,06	0,35	NA	NA	disease	0,81	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,84	low_impact	-1,92	low_impact	-1,48	medium_impact	1,99	0,15	0,8	20,7	14,56	N	0,33	N	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10811	10811	T	G	MI.16415	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	52	18	S	A	Tcc/Gcc	-4,09	0	0	probably_damaging	1	neutral	0,89	neutral	1,53	neutral	-0,63	neutral	-1,73	low_impact	1,77	neutral	0,78	neutral	0,7	deleterious	2,16	17,22	0,21	0,45	NA	NA	neutral	0,31	neutral	0,25	neutral	0,2	6	deleterious	1	neutral	0,45	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	0,71	medium_impact	0,63	0,52	0,8	45,53	8,16	N	0,27	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10811	10811	T	C	MI.16416	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	52	18	S	P	Tcc/Ccc	-4,09	0	0	probably_damaging	1	neutral	0,32	neutral	1,45	neutral	-2,51	deleterious	-3,15	medium_impact	3,12	damaging	0,53	neutral	0,32	deleterious	3,74	23,3	0,1	0,4	NA	NA	disease	0,86	neutral	0,4	disease	0,75	5	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	0,02	medium_impact	1,96	0,43	0,8	45,53	8,16	N	0,4	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10811	10811	T	A	MI.16417	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	52	18	S	T	Tcc/Acc	-4,09	0	0	probably_damaging	1	neutral	0,76	neutral	1,54	neutral	-0,44	neutral	-1,19	low_impact	1,46	neutral	0,77	neutral	0,9	deleterious	1,99	16,15	0,13	0,4	NA	NA	neutral	0,22	neutral	0,2	neutral	0,2	6	deleterious	1	neutral	0,38	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	0,48	medium_impact	0,32	0,48	0,8	45,53	8,16	N	0,32	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10812	10812	C	T	MI.16418	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	53	18	S	F	tCc/tTc	0,29	0	0	probably_damaging	1	neutral	0,34	neutral	1,48	neutral	-1,48	deleterious	-3,81	medium_impact	3,12	neutral	0,7	neutral	0,41	deleterious	4,02	23,6	0,07	0,35	NA	NA	disease	0,73	neutral	0,37	disease	0,54	1	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,04	medium_impact	1,96	0,2	0,8	45,53	8,16	N	0,39	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10812	10812	C	G	MI.16419	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	53	18	S	C	tCc/tGc	0,29	0	0	probably_damaging	1	neutral	0,14	neutral	1,47	neutral	-1,69	deleterious	-3,09	medium_impact	2,58	neutral	0,76	neutral	0,56	deleterious	3,31	22,9	0,09	0,35	NA	NA	disease	0,65	neutral	0,3	neutral	0,47	1	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	-0,24	medium_impact	1,43	0,44	0,8	45,53	8,16	N	0,43	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8459	8459	A	T	MI.1642	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	94	32	N	Y	Aac/Tac	-2,65	0	0	probably_damaging	1	neutral	1	neutral	1,49	deleterious	-3,07	deleterious	-2,81	low_impact	1,07	neutral	1	neutral	0,74	neutral	0,95	10,37	0,58788784	0,85	neutral	0,31	neutral	0,15	disease	0,56	neutral	0,07	9	deleterious	0,99	deleterious	0,5	neutral	-2	deleterious	0,67	low_impact	-3,6	high_impact	1,98	medium_impact	-0,18	0,47	0,85	13,24	7,92	N	0,3	N	0,11	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10812	10812	C	A	MI.16420	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	53	18	S	Y	tCc/tAc	0,29	0	0	probably_damaging	1	neutral	0,46	neutral	1,45	neutral	-2,48	deleterious	-3,83	medium_impact	3,12	neutral	0,71	neutral	0,37	deleterious	3,81	23,4	0,06	0,35	NA	NA	disease	0,78	disease	0,58	disease	0,75	5	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,16	medium_impact	1,96	0,33	0,8	45,53	8,16	N	0,31	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10814	10814	A	G	MI.16421	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	55	19	K	E	Aaa/Gaa	-8,01	0	0	possibly_damaging	0,72	neutral	0,21	neutral	1,45	neutral	-1,05	neutral	-1,55	medium_impact	2,76	neutral	0,78	neutral	0,42	deleterious	2,46	19,18	0,18	0,45	NA	NA	disease	0,77	disease	0,57	disease	0,71	4	neutral	0,84	neutral	0,25	NA	0	deleterious	0,79	low_impact	-1,1	medium_impact	-0,12	medium_impact	1,61	0,46	0,8	21,35	16,46	N	0,37	N	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10814	10814	A	C	MI.16422	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	55	19	K	Q	Aaa/Caa	-8,01	0	0	possibly_damaging	0,86	neutral	0,13	neutral	1,41	neutral	-1,73	neutral	-1,52	medium_impact	2,42	neutral	0,79	neutral	0,57	deleterious	2,03	16,38	0,26	0,45	NA	NA	disease	0,57	neutral	0,41	neutral	0,5	0	neutral	0,94	neutral	0,14	NA	0	deleterious	0,74	low_impact	-1,46	medium_impact	-0,26	medium_impact	1,27	0,43	0,8	21,35	16,46	N	0,43	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10815	10815	A	T	MI.16423	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	56	19	K	M	aAa/aTa	-0,17	0	0	probably_damaging	0,96	deleterious	0,04	neutral	1,34	deleterious	-3,68	deleterious	-2,77	medium_impact	2,76	neutral	0,8	neutral	0,54	deleterious	3,72	23,3	0,09	0,35	NA	NA	disease	0,57	disease	0,62	disease	0,71	4	deleterious	0,99	neutral	0,04	deleterious	5	deleterious	0,75	low_impact	-2,01	medium_impact	-0,57	medium_impact	1,61	0,16	0,8	21,35	16,46	N	0,36	N	0,73	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10815	10815	A	C	MI.16424	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	56	19	K	T	aAa/aCa	-0,17	0	0	benign	0,09	neutral	0,21	neutral	1,41	neutral	-1,75	neutral	-2,16	medium_impact	2,21	neutral	0,72	neutral	0,83	deleterious	2,08	16,74	0,11	0,4	NA	NA	disease	0,53	disease	0,53	neutral	0,5	0	neutral	0,77	deleterious	0,56	neutral	-3	deleterious	0,74	medium_impact	0,23	medium_impact	-0,12	medium_impact	1,06	0,21	0,8	21,35	16,46	N	0,42	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10816	10816	A	T	MI.16425	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	57	19	K	N	aaA/aaT	0,06	0	0	benign	0,08	neutral	0,47	neutral	1,49	neutral	-0,72	neutral	-1,44	low_impact	1,15	neutral	0,74	neutral	0,97	deleterious	1,93	15,75	0,35	0,5	NA	NA	neutral	0,45	neutral	0,35	neutral	0,21	6	neutral	0,47	deleterious	0,7	neutral	-6	deleterious	0,75	medium_impact	0,28	medium_impact	0,17	medium_impact	0,01	0,35	0,8	21,35	16,46	N	0,42	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10816	10816	A	C	MI.16426	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	57	19	K	N	aaA/aaC	0,06	0	0	benign	0,08	neutral	0,47	neutral	1,49	neutral	-0,72	neutral	-1,44	low_impact	1,15	neutral	0,74	neutral	0,97	deleterious	1,85	15,29	0,35	0,5	NA	NA	neutral	0,45	neutral	0,35	neutral	0,21	6	neutral	0,47	deleterious	0,7	neutral	-6	deleterious	0,75	medium_impact	0,28	medium_impact	0,17	medium_impact	0,01	0,35	0,8	21,35	16,46	N	0,42	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10817	10817	A	C	MI.16427	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	58	20	K	Q	Aaa/Caa	-3,4	0	0	benign	0,41	neutral	0,54	neutral	1,5	neutral	-0,91	neutral	-0,56	neutral_impact	0,57	neutral	0,77	neutral	0,81	neutral	0,96	10,44	0,2	0,45	NA	NA	neutral	0,33	neutral	0,3	neutral	0,18	6	neutral	0,41	deleterious	0,57	neutral	-6	deleterious	0,47	medium_impact	-0,57	medium_impact	0,24	medium_impact	-0,56	0,31	0,8	12,42	14,19	N	0,28	N	0,47	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10817	10817	A	G	MI.16428	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	58	20	K	E	Aaa/Gaa	-3,4	0	0	benign	0,18	neutral	0,44	neutral	1,51	neutral	-0,45	neutral	-0,62	low_impact	1,54	neutral	0,78	neutral	0,65	deleterious	0	2,55	0,17	0,45	NA	NA	disease	0,63	disease	0,53	disease	0,58	2	neutral	0,47	deleterious	0,63	neutral	-6	neutral	0,34	medium_impact	-0,1	medium_impact	0,14	medium_impact	0,4	0,42	0,8	12,42	14,19	N	0,26	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10818	10818	A	T	MI.16429	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	59	20	K	M	aAa/aTa	-3,86	0	0	possibly_damaging	0,79	neutral	0,18	neutral	1,42	neutral	-2,89	neutral	-1,72	low_impact	0,85	neutral	0,81	neutral	0,77	deleterious	2,29	18,11	0,11	0,4	NA	NA	neutral	0,34	neutral	0,36	neutral	0,16	7	neutral	0,89	neutral	0,2	neutral	-3	deleterious	0,62	low_impact	-1,26	medium_impact	-0,17	medium_impact	-0,29	0,17	0,8	12,42	14,19	N	0,36	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8459	8459	A	G	MI.1643	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	94	32	N	D	Aac/Gac	-2,65	0	0	probably_damaging	0,97	neutral	0,21	neutral	2,18	neutral	2,95	deleterious	-2,58	low_impact	1,42	neutral	1	neutral	0,68	deleterious	2,54	19,7	0,84955088	0,9	neutral	0,28	neutral	0,2	disease	0,66	neutral	0,11	8	deleterious	0,98	neutral	0,12	neutral	-2	deleterious	0,66	low_impact	-2,19	medium_impact	-0,03	medium_impact	0,12	0,43	0,85	13,24	7,92	N	0,52	P	0,42	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10818	10818	A	C	MI.16430	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	59	20	K	T	aAa/aCa	-3,86	0	0	benign	0,01	neutral	0,5	neutral	1,48	neutral	-1,1	neutral	-0,76	low_impact	0,85	neutral	0,73	neutral	0,86	neutral	-0,25	0,86	0,11	0,4	NA	NA	neutral	0,3	neutral	0,34	neutral	0,15	7	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,12	medium_impact	1,16	medium_impact	0,2	medium_impact	-0,29	0,22	0,8	12,42	14,19	N	0,35	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10819	10819	A	C	MI.16431	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	60	20	K	N	aaA/aaC	-3,4	0	0,01	benign	0,01	neutral	0,6	neutral	1,53	neutral	-0,97	neutral	0,44	neutral_impact	-1,03	neutral	0,83	neutral	0,98	neutral	-0,25	0,87	0,3	0,45	NA	NA	neutral	0,31	neutral	0,32	neutral	0,15	7	neutral	0,39	deleterious	0,8	neutral	-6	neutral	0,38	medium_impact	1,16	medium_impact	0,3	low_impact	-2,15	0,46	0,8	12,42	14,19	N	0,26	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10819	10819	A	T	MI.16432	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	60	20	K	N	aaA/aaT	-3,4	0	0,01	benign	0,01	neutral	0,6	neutral	1,53	neutral	-0,97	neutral	0,44	neutral_impact	-1,03	neutral	0,83	neutral	0,98	neutral	-0,22	1	0,3	0,45	NA	NA	neutral	0,31	neutral	0,32	neutral	0,15	7	neutral	0,39	deleterious	0,8	neutral	-6	neutral	0,38	medium_impact	1,16	medium_impact	0,3	low_impact	-2,15	0,46	0,8	12,42	14,19	N	0,26	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10820	10820	C	A	MI.16433	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	61	21	H	N	Cac/Aac	-7,32	0	0	benign	0	neutral	0,5	neutral	1,68	neutral	1,74	neutral	1,01	neutral_impact	-1,35	neutral	0,83	neutral	0,98	deleterious	0,49	7,35	0,19	0,45	NA	NA	neutral	0,33	neutral	0,35	neutral	0,13	7	neutral	0,5	deleterious	0,75	neutral	-6	neutral	0,31	high_impact	2,1	medium_impact	0,2	low_impact	-2,46	0,63	0,8	31,15	15,96	N	0,31	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10820	10820	C	T	MI.16434	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	61	21	H	Y	Cac/Tac	-7,32	0	0	benign	0,36	neutral	0,23	neutral	1,56	neutral	-0,96	neutral	-1,37	low_impact	1,04	neutral	0,75	neutral	0,63	neutral	1,78	14,87	0,16	0,45	NA	NA	disease	0,51	neutral	0,48	neutral	0,46	1	neutral	0,73	neutral	0,44	neutral	-6	deleterious	0,57	medium_impact	-0,48	medium_impact	-0,09	medium_impact	-0,1	0,41	0,8	31,15	15,96	N	0,37	N	0,24	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10820	10820	C	G	MI.16435	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	61	21	H	D	Cac/Gac	-7,32	0	0	benign	0	neutral	0,06	neutral	1,62	neutral	0,85	neutral	-0,16	neutral_impact	0,34	neutral	0,74	neutral	0,63	deleterious	1,85	15,31	0,05	0,35	NA	NA	disease	0,6	disease	0,62	disease	0,71	4	neutral	0,94	deleterious	0,53	neutral	-6	deleterious	0,45	high_impact	2,1	medium_impact	-0,47	medium_impact	-0,79	0,56	0,8	31,15	15,96	N	0,38	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10821	10821	A	T	MI.16436	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	62	21	H	L	cAc/cTc	0,06	0	0	benign	0,11	neutral	0,17	neutral	1,59	neutral	0,16	neutral	-1,83	neutral_impact	0,49	neutral	0,73	neutral	0,79	neutral	1,59	13,79	0,06	0,35	NA	NA	disease	0,57	disease	0,56	disease	0,62	2	neutral	0,81	deleterious	0,53	neutral	-6	neutral	0,42	medium_impact	0,14	medium_impact	-0,18	medium_impact	-0,64	0,22	0,8	31,15	15,96	N	0,39	N	0,45	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10821	10821	A	G	MI.16437	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	62	21	H	R	cAc/cGc	0,06	0	0	benign	0,01	neutral	0,12	neutral	1,64	neutral	1,24	neutral	0,48	neutral_impact	0,14	neutral	0,83	neutral	0,93	deleterious	0,65	8,48	0,13	0,4	NA	NA	disease	0,59	neutral	0,32	neutral	0,47	1	neutral	0,88	deleterious	0,56	neutral	-6	neutral	0,2	medium_impact	1,16	medium_impact	-0,28	medium_impact	-0,99	0,33	0,8	31,15	15,96	N	0,35	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10821	10821	A	C	MI.16438	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	62	21	H	P	cAc/cCc	0,06	0	0	benign	0,2	neutral	0,06	neutral	1,58	neutral	-0,21	neutral	-0,85	low_impact	1,04	neutral	0,76	neutral	0,81	neutral	1,39	12,76	0,06	0,35	NA	NA	disease	0,77	disease	0,56	disease	0,55	1	neutral	0,93	neutral	0,43	neutral	-6	deleterious	0,66	medium_impact	-0,15	medium_impact	-0,47	medium_impact	-0,1	0,44	0,8	31,15	15,96	N	0,35	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10822	10822	C	G	MI.16439	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	63	21	H	Q	caC/caG	-0,4	0	0	benign	0,01	neutral	0,12	neutral	1,66	neutral	1,47	neutral	0,43	neutral_impact	0,69	neutral	0,8	neutral	0,85	neutral	1,45	13,07	0,13	0,4	NA	NA	neutral	0,38	neutral	0,48	neutral	0,15	7	neutral	0,88	deleterious	0,56	neutral	-6	neutral	0,38	medium_impact	1,16	medium_impact	-0,28	medium_impact	-0,44	0,65	0,8	31,15	15,96	N	0,39	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8460	8460	A	G	MI.1644	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	95	32	N	S	aAc/aGc	-4,04	0	0	probably_damaging	0,97	neutral	0,5	neutral	1,6	neutral	0,17	neutral	-1,61	neutral_impact	0,64	neutral	1	neutral	0,93	neutral	1,25	12	0,84509432	0,9	neutral	0,14	neutral	0,15	disease	0,55	neutral	0,11	8	neutral	0,97	neutral	0,27	neutral	-2	deleterious	0,63	low_impact	-2,19	medium_impact	0,29	medium_impact	-0,55	0,22	0,85	13,24	7,92	N	0,36	N	0,08	polymorphism	1	0,02	rs1116906	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10822	10822	C	A	MI.16440	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	63	21	H	Q	caC/caA	-0,4	0	0	benign	0,01	neutral	0,12	neutral	1,66	neutral	1,47	neutral	0,43	neutral_impact	0,69	neutral	0,8	neutral	0,85	deleterious	1,87	15,41	0,13	0,4	NA	NA	neutral	0,38	neutral	0,48	neutral	0,15	7	neutral	0,88	deleterious	0,56	neutral	-6	neutral	0,38	medium_impact	1,16	medium_impact	-0,28	medium_impact	-0,44	0,65	0,8	31,15	15,96	N	0,39	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10823	10823	A	C	MI.16441	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	64	22	M	L	Ata/Cta	-4,09	0	0	benign	0,01	neutral	0,63	neutral	1,69	neutral	1,25	neutral	-1,12	low_impact	0,93	neutral	0,75	neutral	0,98	neutral	1,67	14,24	0,19	0,45	NA	NA	neutral	0,31	neutral	0,4	neutral	0,15	7	neutral	0,35	deleterious	0,81	neutral	-6	deleterious	0,55	medium_impact	1,16	medium_impact	0,33	medium_impact	-0,21	0,4	0,8	30,72	22,15	N	0,39	N	0,3	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10823	10823	A	T	MI.16442	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	64	22	M	L	Ata/Tta	-4,09	0	0	benign	0,01	neutral	0,63	neutral	1,69	neutral	1,25	neutral	-1,12	low_impact	0,93	neutral	0,75	neutral	0,98	neutral	1,77	14,81	0,19	0,45	NA	NA	neutral	0,31	neutral	0,4	neutral	0,15	7	neutral	0,35	deleterious	0,81	neutral	-6	deleterious	0,55	medium_impact	1,16	medium_impact	0,33	medium_impact	-0,21	0,4	0,8	30,72	22,15	N	0,38	N	0,3	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10823	10823	A	G	MI.16443	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	64	22	M	V	Ata/Gta	-4,09	0	0	benign	0,18	neutral	0,21	neutral	1,61	neutral	0,32	neutral	-1,84	medium_impact	2,25	neutral	0,77	neutral	0,69	deleterious	2,26	17,9	0,19	0,45	NA	NA	neutral	0,38	disease	0,53	neutral	0,34	3	neutral	0,75	deleterious	0,52	neutral	-3	deleterious	0,61	medium_impact	-0,1	medium_impact	-0,12	medium_impact	1,1	0,48	0,8	30,72	22,15	N	0,41	N	0,34	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10824	10824	T	C	MI.16444	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	65	22	M	T	aTa/aCa	0,06	0	0	benign	0,02	neutral	0,19	neutral	1,59	neutral	0,15	neutral	-2,05	neutral_impact	0,55	neutral	0,71	neutral	0,97	neutral	1,59	13,82	0,11	0,4	NA	NA	neutral	0,38	neutral	0,45	neutral	0,15	7	neutral	0,8	deleterious	0,59	neutral	-6	deleterious	0,71	medium_impact	0,87	medium_impact	-0,15	medium_impact	-0,58	0,26	0,8	30,72	22,15	N	0,43	N	0,02	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10824	10824	T	A	MI.16445	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	65	22	M	K	aTa/aAa	0,06	0	0	possibly_damaging	0,46	neutral	0,24	neutral	1,59	neutral	0,12	neutral	-2,42	low_impact	1,15	neutral	0,78	neutral	0,88	deleterious	2,65	20,5	0,05	0,35	NA	NA	disease	0,54	disease	0,63	neutral	0,48	0	neutral	0,73	neutral	0,39	neutral	-3	deleterious	0,75	medium_impact	-0,65	medium_impact	-0,08	medium_impact	0,01	0,31	0,8	30,72	22,15	N	0,33	N	0,36	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10825	10825	A	T	MI.16446	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	66	22	M	I	atA/atT	-1,09	0	0	benign	0,18	neutral	0,34	neutral	1,61	neutral	0,38	neutral	-1,79	low_impact	1,36	neutral	0,75	neutral	0,79	deleterious	3,24	22,8	0,18	0,45	NA	NA	neutral	0,4	neutral	0,43	neutral	0,16	7	neutral	0,6	deleterious	0,58	neutral	-6	deleterious	0,7	medium_impact	-0,1	medium_impact	0,04	medium_impact	0,22	0,46	0,8	30,72	22,15	N	0,42	N	0,27	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10825	10825	A	C	MI.16447	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	66	22	M	I	atA/atC	-1,09	0	0	benign	0,18	neutral	0,34	neutral	1,61	neutral	0,38	neutral	-1,79	low_impact	1,36	neutral	0,75	neutral	0,79	deleterious	3,19	22,7	0,18	0,45	NA	NA	neutral	0,4	neutral	0,43	neutral	0,16	7	neutral	0,6	deleterious	0,58	neutral	-6	deleterious	0,7	medium_impact	-0,1	medium_impact	0,04	medium_impact	0,22	0,46	0,8	30,72	22,15	N	0,42	N	0,27	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10826	10826	A	C	MI.16448	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	67	23	I	L	Att/Ctt	-0,17	0	0	benign	0,01	neutral	1	neutral	1,79	neutral	1,48	neutral	0,07	neutral_impact	0,19	neutral	0,73	neutral	0,94	deleterious	0,81	9,52	0,19	0,45	NA	NA	neutral	0,08	neutral	0,29	neutral	0,17	7	neutral	0,01	deleterious	1	neutral	-6	deleterious	0,59	medium_impact	1,16	high_impact	1,88	medium_impact	-0,94	0,55	0,8	32,24	23,78	N	0,4	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10826	10826	A	T	MI.16449	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	67	23	I	F	Att/Ttt	-0,17	0	0	possibly_damaging	0,61	neutral	0,31	neutral	1,56	neutral	-0,27	neutral	-2,1	low_impact	1,7	neutral	0,76	neutral	0,67	deleterious	3,46	23	0,1	0,4	NA	NA	neutral	0,45	disease	0,54	neutral	0,36	3	neutral	0,71	neutral	0,35	neutral	-3	deleterious	0,71	medium_impact	-0,9	medium_impact	0,01	medium_impact	0,56	0,56	0,8	32,24	23,78	N	0,37	N	0,58	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8460	8460	A	C	MI.1645	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	95	32	N	T	aAc/aCc	-4,04	0	0	probably_damaging	0,98	neutral	0,53	neutral	1,52	neutral	-1,22	neutral	-1,55	neutral_impact	-0,62	neutral	0,99	neutral	0,95	neutral	1,43	12,96	0,76472473	0,85	neutral	0,15	neutral	0,13	disease	0,53	neutral	0,06	9	deleterious	0,98	neutral	0,28	neutral	-2	deleterious	0,63	low_impact	-2,36	medium_impact	0,32	low_impact	-1,63	0,54	0,85	13,24	7,92	N	0,39	N	0,05	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10826	10826	A	G	MI.16450	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	67	23	I	V	Att/Gtt	-0,17	0	0	benign	0,01	neutral	0,07	neutral	1,59	neutral	0,09	neutral	-0,56	low_impact	1,29	neutral	0,81	neutral	0,98	neutral	1,59	13,78	0,2	0,45	NA	NA	neutral	0,13	neutral	0,4	neutral	0,24	5	neutral	0,93	deleterious	0,53	neutral	-6	deleterious	0,61	medium_impact	1,16	medium_impact	-0,43	medium_impact	0,15	0,38	0,8	32,24	23,78	N	0,48	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	COSM1155500	.	.	.	.	.	.	.	.
chrM	10827	10827	T	G	MI.16451	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	68	23	I	S	aTt/aGt	-3,4	0	0	possibly_damaging	0,75	neutral	0,06	neutral	1,54	neutral	-0,69	deleterious	-3,43	medium_impact	2,4	neutral	0,71	neutral	0,51	deleterious	4,06	23,7	0,06	0,35	NA	NA	disease	0,55	disease	0,61	disease	0,72	4	neutral	0,95	neutral	0,16	NA	0	deleterious	0,75	low_impact	-1,17	medium_impact	-0,47	medium_impact	1,25	0,37	0,8	32,24	23,78	N	0,39	N	0,79	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10827	10827	T	C	MI.16452	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	68	23	I	T	aTt/aCt	-3,4	0	0	possibly_damaging	0,48	neutral	0,07	neutral	1,57	neutral	-0,25	deleterious	-2,68	low_impact	1,7	neutral	0,77	neutral	0,97	deleterious	3,2	22,7	0,09	0,35	NA	NA	neutral	0,33	disease	0,55	neutral	0,34	3	neutral	0,92	neutral	0,3	neutral	-3	deleterious	0,71	medium_impact	-0,69	medium_impact	-0,43	medium_impact	0,56	0,27	0,8	32,24	23,78	N	0,43	N	0,56	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10827	10827	T	A	MI.16453	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	68	23	I	N	aTt/aAt	-3,4	0	0	probably_damaging	0,93	neutral	0,06	neutral	1,51	neutral	-1,27	deleterious	-4,16	medium_impact	2,4	neutral	0,67	neutral	0,5	deleterious	4,4	24,1	0,09	0,35	NA	NA	disease	0,65	disease	0,64	disease	0,74	5	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,77	low_impact	-1,77	medium_impact	-0,47	medium_impact	1,25	0,3	0,8	32,24	23,78	N	0,38	N	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10828	10828	T	G	MI.16454	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	69	23	I	M	atT/atG	4,67	0,69	0	benign	0,17	neutral	0,12	neutral	1,54	neutral	-0,58	neutral	-0,65	low_impact	0,85	neutral	0,72	neutral	0,97	deleterious	1,95	15,88	0,16	0,45	NA	NA	neutral	0,2	neutral	0,39	neutral	0,19	6	neutral	0,86	deleterious	0,48	neutral	-6	deleterious	0,68	medium_impact	-0,07	medium_impact	-0,28	medium_impact	-0,29	0,52	0,8	32,24	23,78	P	0,51	P	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10828	10828	T	A	MI.16455	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	69	23	I	M	atT/atA	4,67	0,69	0	benign	0,17	neutral	0,12	neutral	1,54	neutral	-0,58	neutral	-0,65	low_impact	0,85	neutral	0,72	neutral	0,97	deleterious	2,15	17,19	0,16	0,45	NA	NA	neutral	0,2	neutral	0,39	neutral	0,19	6	neutral	0,86	deleterious	0,48	neutral	-6	deleterious	0,68	medium_impact	-0,07	medium_impact	-0,28	medium_impact	-0,29	0,52	0,8	32,24	23,78	P	0,5	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10829	10829	T	G	MI.16456	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	70	24	W	G	Tga/Gga	-5,7	0	0	probably_damaging	1	deleterious	0	neutral	1,26	deleterious	-3,71	deleterious	-9,83	medium_impact	3,44	damaging	0,56	damaging	0,1	deleterious	3,63	23,2	0,09	0,35	NA	NA	disease	0,8	disease	0,78	disease	0,76	5	deleterious	1	deleterious	0	deleterious	5	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,28	0,33	0,8	47,28	9,14	N	0,41	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10829	10829	T	C	MI.16457	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	70	24	W	R	Tga/Cga	-5,7	0	0	probably_damaging	1	deleterious	0,02	neutral	1,27	deleterious	-3,21	deleterious	-10,58	medium_impact	3,1	damaging	0,57	damaging	0,07	deleterious	3,32	22,9	0,05	0,35	NA	NA	disease	0,85	disease	0,82	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,88	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,94	0,29	0,8	47,28	9,14	N	0,4	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10830	10830	G	C	MI.16458	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	71	24	W	S	tGa/tCa	7,44	1	0	probably_damaging	1	deleterious	0	neutral	1,3	neutral	-2,48	deleterious	-10,57	medium_impact	3,1	damaging	0,53	damaging	0,09	deleterious	3,71	23,3	0,09	0,35	NA	NA	disease	0,84	disease	0,75	disease	0,79	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	medium_impact	1,94	0,29	0,8	47,28	9,14	P	0,51	P	0,93	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10830	10830	G	T	MI.16459	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	71	24	W	L	tGa/tTa	7,44	1	0	probably_damaging	1	deleterious	0,01	neutral	1,36	neutral	-1,55	deleterious	-9,83	medium_impact	3,44	damaging	0,54	damaging	0,07	deleterious	3,97	23,6	0,11	0,4	NA	NA	disease	0,76	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-3,54	medium_impact	-0,92	high_impact	2,28	0,2	0,8	47,28	9,14	P	0,56	P	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8460	8460	A	T	MI.1646	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	95	32	N	I	aAc/aTc	-4,04	0	0	probably_damaging	1	neutral	0,45	neutral	1,48	deleterious	-4,02	deleterious	-3,44	neutral_impact	-0,18	neutral	0,99	neutral	0,91	deleterious	2,08	16,71	0,56070775	0,85	neutral	0,32	neutral	0,24	disease	0,56	neutral	0,1	8	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,24	low_impact	-1,25	0,34	0,85	13,24	7,92	N	0,44	N	0,37	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10831	10831	A	C	MI.16460	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	72	24	W	C	tgA/tgC	6,06	1	0	probably_damaging	1	deleterious	0	neutral	1,25	deleterious	-4,32	deleterious	-9,83	medium_impact	3,44	damaging	0,53	damaging	0,05	deleterious	3,74	23,3	0,09	0,4	NA	NA	disease	0,83	disease	0,77	disease	0,78	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,28	0,35	0,8	47,28	9,14	P	0,54	P	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10831	10831	A	T	MI.16461	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	72	24	W	C	tgA/tgT	6,06	1	0	probably_damaging	1	deleterious	0	neutral	1,25	deleterious	-4,32	deleterious	-9,83	medium_impact	3,44	damaging	0,53	damaging	0,05	deleterious	3,88	23,5	0,09	0,4	NA	NA	disease	0,83	disease	0,77	disease	0,78	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,28	0,35	0,8	47,28	9,14	P	0,55	P	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10832	10832	A	T	MI.16462	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	73	25	I	F	Atc/Ttc	2,37	0,98	0	probably_damaging	0,98	neutral	0,72	neutral	1,52	neutral	-1,29	neutral	-2,17	medium_impact	2,93	neutral	0,74	neutral	0,53	deleterious	2,38	18,71	0,1	0,4	NA	NA	neutral	0,45	neutral	0,4	neutral	0,19	6	neutral	0,97	neutral	0,37	deleterious	1	deleterious	0,72	low_impact	-2,31	medium_impact	0,43	medium_impact	1,77	0,7	0,85	16,56	18,19	N	0,49	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10832	10832	A	G	MI.16463	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	73	25	I	V	Atc/Gtc	2,37	0,98	0	possibly_damaging	0,73	neutral	0,53	neutral	1,57	neutral	0,03	neutral	-0,23	medium_impact	2,58	neutral	0,81	neutral	0,88	neutral	1,63	13,99	0,26	0,45	NA	NA	neutral	0,16	neutral	0,37	neutral	0,23	5	neutral	0,69	neutral	0,4	NA	0	deleterious	0,63	low_impact	-1,12	medium_impact	0,23	medium_impact	1,43	0,51	0,8	16,56	18,19	N	0,48	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10832	10832	A	C	MI.16464	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	73	25	I	L	Atc/Ctc	2,37	0,98	0	possibly_damaging	0,73	neutral	0,7	neutral	1,6	neutral	0,3	neutral	-0,91	medium_impact	2,12	neutral	0,75	neutral	0,7	deleterious	2,36	18,55	0,16	0,45	NA	NA	neutral	0,27	neutral	0,24	neutral	0,17	7	neutral	0,67	deleterious	0,49	NA	0	deleterious	0,64	low_impact	-1,12	medium_impact	0,41	medium_impact	0,97	0,61	0,8	16,56	18,19	N	0,52	P	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10833	10833	T	A	MI.16465	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	74	25	I	N	aTc/aAc	0,06	0,4	0	probably_damaging	0,97	neutral	0,34	neutral	1,56	neutral	-2,26	deleterious	-3,19	low_impact	1,89	neutral	0,75	neutral	0,61	deleterious	4,26	23,9	0,13	0,4	NA	NA	disease	0,56	neutral	0,42	disease	0,51	0	neutral	0,97	neutral	0,19	neutral	-2	deleterious	0,74	low_impact	-2,14	medium_impact	0,04	medium_impact	0,74	0,36	0,8	16,56	18,19	N	0,34	N	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10833	10833	T	G	MI.16466	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	74	25	I	S	aTc/aGc	0,06	0,4	0	possibly_damaging	0,88	neutral	0,49	neutral	1,64	neutral	-1,16	neutral	-2,37	low_impact	1,58	neutral	0,73	neutral	0,68	deleterious	2,74	21,1	0,07	0,35	NA	NA	neutral	0,35	neutral	0,31	neutral	0,16	7	neutral	0,87	neutral	0,31	neutral	-3	deleterious	0,71	low_impact	-1,53	medium_impact	0,19	medium_impact	0,44	0,31	0,8	16,56	18,19	N	0,35	N	0,74	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10833	10833	T	C	MI.16467	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	74	25	I	T	aTc/aCc	0,06	0,4	0	benign	0,26	neutral	0,6	neutral	1,64	neutral	-0,92	neutral	-1,36	low_impact	1,22	neutral	0,74	neutral	0,97	neutral	1,1	11,22	0,09	0,35	NA	NA	neutral	0,11	neutral	0,26	neutral	0,21	6	neutral	0,29	deleterious	0,67	neutral	-6	deleterious	0,69	medium_impact	-0,29	medium_impact	0,3	medium_impact	0,08	0,44	0,8	16,56	18,19	N	0,36	N	0,21	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10834	10834	C	A	MI.16468	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	75	25	I	M	atC/atA	2,14	0,4	0	probably_damaging	0,98	neutral	0,25	neutral	1,54	neutral	-1,51	neutral	-1,19	medium_impact	2,24	neutral	0,77	neutral	0,74	deleterious	2,47	19,26	0,18	0,45	NA	NA	neutral	0,2	neutral	0,31	neutral	0,2	6	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,7	low_impact	-2,31	medium_impact	-0,07	medium_impact	1,09	0,73	0,85	16,56	18,19	N	0,42	N	0,64	polymorphism	1	0,03	rs386829113	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10834	10834	C	G	MI.16469	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	75	25	I	M	atC/atG	2,14	0,4	0	probably_damaging	0,98	neutral	0,25	neutral	1,54	neutral	-1,51	neutral	-1,19	medium_impact	2,24	neutral	0,77	neutral	0,74	deleterious	2,01	16,28	0,18	0,45	NA	NA	neutral	0,2	neutral	0,31	neutral	0,2	6	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,7	low_impact	-2,31	medium_impact	-0,07	medium_impact	1,09	0,73	0,85	16,56	18,19	N	0,42	N	0,64	polymorphism	1	0,03	rs386829113	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8461	8461	C	G	MI.1647	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	96	32	N	K	aaC/aaG	-3,8	0	0	probably_damaging	0,98	neutral	0,37	neutral	1,55	neutral	-0,62	neutral	-2,33	low_impact	0,87	neutral	1	neutral	0,77	deleterious	2,44	19,1	0,86761339	0,9	neutral	0,19	neutral	0,25	disease	0,65	neutral	0,09	8	deleterious	0,98	neutral	0,2	neutral	-2	deleterious	0,68	low_impact	-2,36	medium_impact	0,16	medium_impact	-0,35	0,62	0,85	13,24	7,92	N	0,45	N	0,39	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10835	10835	A	G	MI.16470	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	76	26	N	D	Aac/Gac	-9,39	0	0	probably_damaging	1	neutral	0,21	neutral	1,53	neutral	-1,31	deleterious	-2,84	medium_impact	2,62	neutral	0,77	damaging	0,11	deleterious	3,58	23,2	0,28	0,45	NA	NA	disease	0,57	disease	0,58	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,12	medium_impact	1,47	0,61	0,8	45,1	8,46	N	0,23	N	0,96	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10835	10835	A	C	MI.16471	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	76	26	N	H	Aac/Cac	-9,39	0	0	probably_damaging	1	neutral	0,55	neutral	1,53	neutral	-1,2	deleterious	-2,96	low_impact	1,93	neutral	0,8	damaging	0,23	neutral	1,73	14,56	0,21	0,45	NA	NA	disease	0,5	disease	0,53	neutral	0,48	0	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	0,25	medium_impact	0,78	0,52	0,8	45,1	8,46	N	0,21	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10835	10835	A	T	MI.16472	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	76	26	N	Y	Aac/Tac	-9,39	0	0	probably_damaging	1	neutral	1	neutral	1,54	neutral	-1,04	deleterious	-4,5	medium_impact	2,97	neutral	0,78	damaging	0,11	deleterious	2,33	18,33	0,1	0,4	NA	NA	disease	0,69	disease	0,54	disease	0,62	2	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,79	low_impact	-3,54	high_impact	1,88	medium_impact	1,81	0,43	0,8	45,1	8,46	N	0,16	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10836	10836	A	T	MI.16473	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	77	26	N	I	aAc/aTc	0,75	0	0	probably_damaging	1	neutral	0,41	neutral	1,63	neutral	0,56	deleterious	-4,79	medium_impact	2,27	neutral	0,76	damaging	0,27	deleterious	2,67	20,6	0,1	0,4	NA	NA	disease	0,69	neutral	0,4	disease	0,53	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,11	medium_impact	1,12	0,32	0,8	45,1	8,46	N	0,28	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10836	10836	A	G	MI.16474	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	77	26	N	S	aAc/aGc	0,75	0	0	probably_damaging	1	neutral	0,47	neutral	1,62	neutral	0,51	neutral	-2,32	low_impact	1,77	neutral	0,77	neutral	0,35	neutral	1,39	12,74	0,32	0,5	NA	NA	neutral	0,31	neutral	0,39	neutral	0,17	7	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,73	low_impact	-3,54	medium_impact	0,17	medium_impact	0,63	0,39	0,8	45,1	8,46	N	0,3	N	0,85	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10836	10836	A	C	MI.16475	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	77	26	N	T	aAc/aCc	0,75	0	0	probably_damaging	1	neutral	0,51	neutral	1,65	neutral	0,81	neutral	-2,36	low_impact	0,92	neutral	0,76	neutral	0,41	neutral	1,09	11,15	0,17	0,45	NA	NA	neutral	0,17	neutral	0,29	neutral	0,18	6	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,7	low_impact	-3,54	medium_impact	0,21	medium_impact	-0,22	0,55	0,8	45,1	8,46	N	0,3	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10837	10837	C	A	MI.16476	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	78	26	N	K	aaC/aaA	3,06	0,02	0	probably_damaging	1	neutral	0,3	neutral	1,56	neutral	-0,42	deleterious	-3,29	medium_impact	2,97	neutral	0,76	damaging	0,1	deleterious	4,07	23,7	0,25	0,45	NA	NA	disease	0,61	disease	0,59	disease	0,72	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0	medium_impact	1,81	0,65	0,8	45,1	8,46	N	0,36	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10837	10837	C	G	MI.16477	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	78	26	N	K	aaC/aaG	3,06	0,02	0	probably_damaging	1	neutral	0,3	neutral	1,56	neutral	-0,42	deleterious	-3,29	medium_impact	2,97	neutral	0,76	damaging	0,1	deleterious	3,62	23,2	0,25	0,45	NA	NA	disease	0,61	disease	0,59	disease	0,72	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0	medium_impact	1,81	0,65	0,8	45,1	8,46	N	0,36	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10838	10838	A	G	MI.16478	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	79	27	T	A	Aca/Gca	-6,16	0	0	benign	0,36	neutral	0,47	neutral	1,53	neutral	-0,59	neutral	-1,33	low_impact	1,68	neutral	0,76	neutral	0,99	neutral	1,78	14,9	0,16	0,45	NA	NA	neutral	0,25	neutral	0,47	neutral	0,18	6	neutral	0,45	deleterious	0,56	neutral	-6	deleterious	0,68	medium_impact	-0,48	medium_impact	0,17	medium_impact	0,54	0,47	0,8	30,72	21,73	N	0,38	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10838	10838	A	T	MI.16479	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	79	27	T	S	Aca/Tca	-6,16	0	0	possibly_damaging	0,52	neutral	0,67	neutral	1,59	neutral	0,01	neutral	-0,68	low_impact	1,17	neutral	0,77	neutral	0,99	neutral	1,06	11,02	0,19	0,45	NA	NA	neutral	0,21	neutral	0,31	neutral	0,18	6	neutral	0,43	deleterious	0,58	neutral	-3	deleterious	0,7	medium_impact	-0,75	medium_impact	0,37	medium_impact	0,03	0,66	0,8	30,72	21,73	N	0,32	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8461	8461	C	A	MI.1648	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	96	32	N	K	aaC/aaA	-3,8	0	0	probably_damaging	0,98	neutral	0,37	neutral	1,55	neutral	-0,62	neutral	-2,33	low_impact	0,87	neutral	1	neutral	0,77	deleterious	2,87	21,7	0,86761339	0,9	neutral	0,19	neutral	0,25	disease	0,65	neutral	0,09	8	deleterious	0,98	neutral	0,2	neutral	-2	deleterious	0,68	low_impact	-2,36	medium_impact	0,16	medium_impact	-0,35	0,62	0,85	13,24	7,92	N	0,45	N	0,39	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10838	10838	A	C	MI.16480	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	79	27	T	P	Aca/Cca	-6,16	0	0	possibly_damaging	0,86	neutral	0,19	neutral	1,45	neutral	-2,42	neutral	-1,55	medium_impact	2,28	neutral	0,77	neutral	0,96	deleterious	1,96	15,97	0,08	0,35	NA	NA	disease	0,68	disease	0,54	disease	0,52	0	neutral	0,92	neutral	0,17	NA	0	deleterious	0,78	low_impact	-1,46	medium_impact	-0,15	medium_impact	1,13	0,44	0,8	30,72	21,73	N	0,4	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10839	10839	C	A	MI.16481	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	80	27	T	K	aCa/aAa	-3,4	0	0	possibly_damaging	0,64	neutral	0,33	neutral	1,48	neutral	-1,35	neutral	-2,07	medium_impact	2,83	neutral	0,73	neutral	0,41	deleterious	4,21	23,9	0,08	0,35	NA	NA	disease	0,69	disease	0,6	disease	0,72	4	neutral	0,71	neutral	0,35	NA	0	deleterious	0,78	medium_impact	-0,95	medium_impact	0,03	medium_impact	1,67	0,44	0,8	30,72	21,73	N	0,35	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10839	10839	C	T	MI.16482	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	80	27	T	M	aCa/aTa	-3,4	0	0	benign	0,12	neutral	0,33	neutral	1,47	neutral	-1,55	neutral	-1,67	medium_impact	2,13	neutral	0,72	neutral	0,78	deleterious	2,68	20,7	0,1	0,4	NA	NA	neutral	0,4	neutral	0,41	neutral	0,18	6	neutral	0,62	deleterious	0,61	neutral	-3	deleterious	0,7	medium_impact	0,1	medium_impact	0,03	medium_impact	0,98	0,55	0,8	30,72	21,73	N	0,44	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10841	10841	A	T	MI.16483	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	82	28	T	S	Acc/Tcc	-11,93	0	0	possibly_damaging	0,8	neutral	0,41	neutral	1,42	neutral	-1,71	neutral	-1,6	medium_impact	2,63	neutral	0,78	neutral	0,83	deleterious	2,45	19,12	0,21	0,45	NA	NA	neutral	0,46	neutral	0,42	neutral	0,25	5	neutral	0,81	neutral	0,31	NA	0	deleterious	0,76	low_impact	-1,28	medium_impact	0,11	medium_impact	1,48	0,58	0,8	17,43	15,51	N	0,42	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10841	10841	A	C	MI.16484	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	82	28	T	P	Acc/Ccc	-11,93	0	0	benign	0,12	neutral	0,21	neutral	1,36	deleterious	-3,67	deleterious	-3,43	medium_impact	3,18	neutral	0,66	neutral	0,31	deleterious	3,71	23,3	0,1	0,4	NA	NA	disease	0,79	disease	0,68	disease	0,72	4	neutral	0,76	deleterious	0,55	neutral	-3	deleterious	0,83	medium_impact	0,1	medium_impact	-0,12	high_impact	2,02	0,39	0,8	17,43	15,51	N	0,36	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10841	10841	A	G	MI.16485	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	82	28	T	A	Acc/Gcc	-11,93	0	0	possibly_damaging	0,64	neutral	0,51	neutral	1,45	neutral	-1,29	neutral	-2,42	medium_impact	2,38	neutral	0,77	neutral	0,6	deleterious	3,69	23,3	0,2	0,45	NA	NA	neutral	0,41	disease	0,56	neutral	0,38	2	neutral	0,62	neutral	0,44	NA	0	deleterious	0,73	medium_impact	-0,95	medium_impact	0,21	medium_impact	1,23	0,46	0,8	17,43	15,51	N	0,33	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10842	10842	C	T	MI.16486	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	83	28	T	I	aCc/aTc	1,21	0	0	possibly_damaging	0,83	neutral	0,46	neutral	1,53	neutral	-0,42	deleterious	-2,98	medium_impact	2,38	neutral	0,71	neutral	0,62	deleterious	2,54	19,74	0,12	0,4	NA	NA	disease	0,68	neutral	0,45	disease	0,52	0	neutral	0,82	neutral	0,32	NA	0	deleterious	0,77	low_impact	-1,37	medium_impact	0,16	medium_impact	1,23	0,68	0,85	17,43	15,51	N	0,35	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10842	10842	C	G	MI.16487	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	83	28	T	S	aCc/aGc	1,21	0	0	possibly_damaging	0,8	neutral	0,41	neutral	1,42	neutral	-1,71	neutral	-1,6	medium_impact	2,63	neutral	0,78	neutral	0,83	deleterious	2,12	16,97	0,21	0,45	NA	NA	neutral	0,46	neutral	0,42	neutral	0,25	5	neutral	0,81	neutral	0,31	NA	0	deleterious	0,76	low_impact	-1,28	medium_impact	0,11	medium_impact	1,48	0,58	0,8	17,43	15,51	N	0,37	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10842	10842	C	A	MI.16488	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	83	28	T	N	aCc/aAc	1,21	0	0	probably_damaging	0,96	neutral	0,31	neutral	1,37	deleterious	-3,2	deleterious	-2,65	medium_impact	2,84	neutral	0,71	neutral	0,41	deleterious	3,53	23,1	0,2	0,45	NA	NA	disease	0,62	disease	0,56	disease	0,66	3	neutral	0,96	neutral	0,18	deleterious	1	deleterious	0,76	low_impact	-2,01	medium_impact	0,01	medium_impact	1,68	0,46	0,8	17,43	15,51	N	0,37	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10844	10844	A	G	MI.16489	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	85	29	T	A	Acc/Gcc	-5,24	0	0	benign	0,36	neutral	0,73	neutral	1,6	neutral	0,17	neutral	-0,24	neutral_impact	0,29	neutral	0,71	neutral	1	neutral	1,47	13,17	0,18	0,45	NA	NA	neutral	0,09	neutral	0,32	neutral	0,21	6	neutral	0,26	deleterious	0,69	neutral	-6	deleterious	0,64	medium_impact	-0,48	medium_impact	0,44	medium_impact	-0,84	0,39	0,8	11,76	11,57	N	0,34	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8462	8462	T	C	MI.1649	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	97	33	Y	H	Tac/Cac	-8,2	0	0	probably_damaging	0,99	neutral	0,54	neutral	1,56	deleterious	-3,82	deleterious	-3,59	low_impact	1,42	neutral	1	neutral	0,92	deleterious	2,49	19,39	0,57564883	0,85	disease	0,65	neutral	0,35	disease	0,63	neutral	0,24	5	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,81	low_impact	-2,65	medium_impact	0,33	medium_impact	0,12	0,24	0,85	NA	NA	N	0,41	N	0,23	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10844	10844	A	T	MI.16490	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	85	29	T	S	Acc/Tcc	-5,24	0	0	benign	0,04	neutral	0,54	neutral	1,57	neutral	-0,21	neutral	-0,35	neutral_impact	0,64	neutral	0,75	neutral	0,98	neutral	1,46	13,08	0,25	0,45	NA	NA	neutral	0,13	neutral	0,33	neutral	0,21	6	neutral	0,41	deleterious	0,75	neutral	-6	deleterious	0,66	medium_impact	0,58	medium_impact	0,24	medium_impact	-0,49	0,52	0,8	11,76	11,57	N	0,36	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10844	10844	A	C	MI.16491	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	85	29	T	P	Acc/Ccc	-5,24	0	0	possibly_damaging	0,75	neutral	0,19	neutral	1,49	neutral	-2,35	neutral	-1,85	medium_impact	2,43	neutral	0,65	neutral	0,38	deleterious	3,65	23,2	0,07	0,35	NA	NA	disease	0,64	disease	0,6	disease	0,68	4	neutral	0,87	neutral	0,22	NA	0	deleterious	0,76	low_impact	-1,17	medium_impact	-0,15	medium_impact	1,28	0,36	0,8	11,76	11,57	N	0,35	N	0,68	polymorphism	1	0,02	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	10845	10845	C	T	MI.16492	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	86	29	T	I	aCc/aTc	-7,32	0	0	benign	0,04	neutral	0,55	neutral	1,64	neutral	0,6	neutral	-0,13	low_impact	1,1	neutral	0,74	neutral	0,99	deleterious	2,16	17,24	0,13	0,4	NA	NA	neutral	0,37	neutral	0,37	neutral	0,14	7	neutral	0,4	deleterious	0,76	neutral	-6	deleterious	0,69	medium_impact	0,58	medium_impact	0,25	medium_impact	-0,04	0,55	0,8	11,76	11,57	N	0,36	N	0,45	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10845	10845	C	A	MI.16493	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	86	29	T	N	aCc/aAc	-7,32	0	0	possibly_damaging	0,61	neutral	0,3	neutral	1,5	neutral	-1,98	neutral	-1,59	medium_impact	2,43	neutral	0,8	neutral	0,58	deleterious	2,33	18,38	0,25	0,45	NA	NA	neutral	0,36	neutral	0,45	neutral	0,16	7	neutral	0,72	neutral	0,35	NA	0	deleterious	0,68	medium_impact	-0,9	medium_impact	0	medium_impact	1,28	0,53	0,8	11,76	11,57	N	0,39	N	0,36	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10845	10845	C	G	MI.16494	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	86	29	T	S	aCc/aGc	-7,32	0	0	benign	0,04	neutral	0,54	neutral	1,57	neutral	-0,21	neutral	-0,35	neutral_impact	0,64	neutral	0,75	neutral	0,98	neutral	1,19	11,7	0,25	0,45	NA	NA	neutral	0,13	neutral	0,33	neutral	0,21	6	neutral	0,41	deleterious	0,75	neutral	-6	deleterious	0,66	medium_impact	0,58	medium_impact	0,24	medium_impact	-0,49	0,52	0,8	11,76	11,57	N	0,35	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10847	10847	C	G	MI.16495	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	88	30	H	D	Cac/Gac	-20	0	0	possibly_damaging	0,76	neutral	0,16	neutral	1,54	neutral	-1,91	deleterious	-4,45	medium_impact	2,68	neutral	0,72	neutral	0,4	deleterious	3,62	23,2	0,07	0,35	NA	NA	disease	0,69	disease	0,7	disease	0,76	5	neutral	0,89	neutral	0,2	NA	0	deleterious	0,78	low_impact	-1,19	medium_impact	-0,2	medium_impact	1,53	0,51	0,8	15,69	16,24	N	0,37	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10847	10847	C	T	MI.16496	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	88	30	H	Y	Cac/Tac	-20	0	0	benign	0,04	neutral	1	neutral	1,65	neutral	1,02	neutral	-0,76	neutral_impact	0,06	neutral	0,83	neutral	0,98	neutral	1,68	14,31	0,16	0,45	NA	NA	neutral	0,3	neutral	0,45	neutral	0,17	7	neutral	0,04	deleterious	0,98	neutral	-6	deleterious	0,72	medium_impact	0,58	high_impact	1,88	low_impact	-1,07	0,39	0,8	15,69	16,24	N	0,28	N	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10847	10847	C	A	MI.16497	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	88	30	H	N	Cac/Aac	-20	0	0	possibly_damaging	0,56	neutral	0,38	neutral	1,58	neutral	-0,16	deleterious	-3,25	low_impact	1,88	neutral	0,76	neutral	0,7	deleterious	2,51	19,52	0,33	0,5	NA	NA	neutral	0,4	disease	0,52	neutral	0,33	3	neutral	0,63	neutral	0,41	neutral	-3	deleterious	0,72	medium_impact	-0,82	medium_impact	0,08	medium_impact	0,73	0,42	0,8	15,69	16,24	N	0,39	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10848	10848	A	T	MI.16498	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	89	30	H	L	cAc/cTc	-4,78	0	0	possibly_damaging	0,56	neutral	0,62	neutral	1,7	neutral	1,57	deleterious	-4,84	low_impact	1,79	neutral	0,73	neutral	0,64	deleterious	3,7	23,3	0,1	0,4	NA	NA	disease	0,73	disease	0,53	disease	0,54	1	neutral	0,49	deleterious	0,53	neutral	-3	deleterious	0,77	medium_impact	-0,82	medium_impact	0,32	medium_impact	0,65	0,27	0,8	15,69	16,24	N	0,31	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10848	10848	A	C	MI.16499	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	89	30	H	P	cAc/cCc	-4,78	0	0	probably_damaging	0,93	neutral	0,16	neutral	1,54	neutral	-1,82	deleterious	-5	medium_impact	2,68	neutral	0,64	neutral	0,33	deleterious	3,03	22,3	0,08	0,35	NA	NA	disease	0,85	disease	0,72	disease	0,79	6	neutral	0,96	neutral	0,12	deleterious	1	deleterious	0,83	low_impact	-1,77	medium_impact	-0,2	medium_impact	1,53	0,31	0,8	15,69	16,24	N	0,3	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8603	8603	T	C	MI.165	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	77	26	F	S	tTt/tCt	-0,33	0	0	benign	0,43	deleterious	0,03	neutral	4,33	neutral	-0,63	deleterious	-4,76	low_impact	1,58	neutral	0,93	neutral	0,64	deleterious	2,42	18,98	0,39	0,65	disease	0,56	disease	0,54	disease	0,57	disease	0,65	3	neutral	0,97	neutral	0,3	neutral	-2	neutral	0,36	medium_impact	-0,64	medium_impact	-0,56	medium_impact	0,26	0,37	0,9	15,49	8,03	N	0,43	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8462	8462	T	G	MI.1650	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	97	33	Y	D	Tac/Gac	-8,2	0	0	probably_damaging	1	neutral	0,23	neutral	1,55	deleterious	-4,75	deleterious	-7,78	medium_impact	2,69	neutral	0,99	neutral	0,33	deleterious	3,93	23,5	0,38394872	0,85	disease	0,89	neutral	0,43	disease	0,75	neutral	0,34	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	-0,01	medium_impact	1,21	0,3	0,85	NA	NA	N	0,49	N	0,74	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10848	10848	A	G	MI.16500	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	89	30	H	R	cAc/cGc	-4,78	0	0	possibly_damaging	0,81	neutral	0,28	neutral	1,55	neutral	-1,07	deleterious	-3,81	medium_impact	2,68	neutral	0,78	neutral	0,41	deleterious	2,79	21,3	0,15	0,45	NA	NA	disease	0,72	disease	0,64	disease	0,73	5	neutral	0,85	neutral	0,24	NA	0	deleterious	0,79	low_impact	-1,31	medium_impact	-0,03	medium_impact	1,53	0,31	0,8	15,69	16,24	N	0,3	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10849	10849	C	G	MI.16501	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	90	30	H	Q	caC/caG	5,36	0,53	0	possibly_damaging	0,87	neutral	0,41	neutral	1,6	neutral	0,27	deleterious	-3,25	low_impact	1,4	neutral	0,76	neutral	0,78	neutral	1,61	13,9	0,21	0,45	NA	NA	neutral	0,33	neutral	0,49	neutral	0,17	7	neutral	0,87	neutral	0,27	neutral	-3	deleterious	0,71	low_impact	-1,49	medium_impact	0,11	medium_impact	0,26	0,39	0,8	15,69	16,24	N	0,44	N	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10849	10849	C	A	MI.16502	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	90	30	H	Q	caC/caA	5,36	0,53	0	possibly_damaging	0,87	neutral	0,41	neutral	1,6	neutral	0,27	deleterious	-3,25	low_impact	1,4	neutral	0,76	neutral	0,78	deleterious	1,97	16,05	0,21	0,45	NA	NA	neutral	0,33	neutral	0,49	neutral	0,17	7	neutral	0,87	neutral	0,27	neutral	-3	deleterious	0,71	low_impact	-1,49	medium_impact	0,11	medium_impact	0,26	0,39	0,8	15,69	16,24	N	0,44	N	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10850	10850	A	G	MI.16503	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	91	31	S	G	Agc/Ggc	-8,01	0	0	benign	0,08	neutral	0,33	neutral	1,32	neutral	-2,8	deleterious	-2,92	low_impact	1,75	neutral	0,81	neutral	0,91	deleterious	2,02	16,35	0,19	0,45	NA	NA	disease	0,54	disease	0,51	neutral	0,44	1	neutral	0,63	deleterious	0,63	neutral	-6	deleterious	0,74	medium_impact	0,28	medium_impact	0,03	medium_impact	0,61	0,4	0,8	47,71	9,69	N	0,35	N	0,27	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10850	10850	A	C	MI.16504	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	91	31	S	R	Agc/Cgc	-8,01	0	0	probably_damaging	0,97	neutral	0,29	neutral	1,32	neutral	-2,61	deleterious	-3,74	medium_impact	3,35	neutral	0,64	neutral	0,4	deleterious	3,44	23	0,11	0,4	NA	NA	disease	0,84	disease	0,76	disease	0,79	6	neutral	0,97	neutral	0,16	deleterious	1	deleterious	0,85	low_impact	-2,14	medium_impact	-0,02	high_impact	2,19	0,41	0,8	47,71	9,69	N	0,42	N	0,93	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10850	10850	A	T	MI.16505	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	91	31	S	C	Agc/Tgc	-8,01	0	0	probably_damaging	0,98	neutral	0,15	neutral	1,28	deleterious	-4,65	deleterious	-3,73	medium_impact	3,35	neutral	0,77	neutral	0,39	deleterious	3,02	22,3	0,12	0,4	NA	NA	disease	0,71	disease	0,6	disease	0,66	3	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,78	low_impact	-2,31	medium_impact	-0,22	high_impact	2,19	0,28	0,8	47,71	9,69	N	0,37	N	0,54	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10851	10851	G	T	MI.16506	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	92	31	S	I	aGc/aTc	4,67	1	0	probably_damaging	0,98	neutral	0,38	neutral	1,31	neutral	-2,88	deleterious	-4,49	medium_impact	2,8	neutral	0,67	neutral	0,52	deleterious	3,87	23,5	0,11	0,4	NA	NA	disease	0,86	disease	0,66	disease	0,7	4	neutral	0,98	neutral	0,2	deleterious	1	deleterious	0,83	low_impact	-2,31	medium_impact	0,08	medium_impact	1,64	0,25	0,8	47,71	9,69	P	0,53	P	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10851	10851	G	C	MI.16507	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	92	31	S	T	aGc/aCc	4,67	1	0	possibly_damaging	0,85	neutral	0,39	neutral	1,37	neutral	-1,72	neutral	-2,25	medium_impact	2,8	neutral	0,74	neutral	0,62	deleterious	3,14	22,6	0,21	0,45	NA	NA	disease	0,51	neutral	0,47	neutral	0,43	1	neutral	0,85	neutral	0,27	NA	0	deleterious	0,75	low_impact	-1,43	medium_impact	0,09	medium_impact	1,64	0,49	0,8	47,71	9,69	P	0,63	P	0,69	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10851	10851	G	A	MI.16508	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	92	31	S	N	aGc/aAc	4,67	1	0	probably_damaging	0,91	neutral	0,34	neutral	1,33	neutral	-2,47	neutral	-2,25	medium_impact	3,35	neutral	0,68	neutral	0,45	deleterious	3,34	22,9	0,42	0,55	NA	NA	disease	0,61	disease	0,66	disease	0,6	2	neutral	0,92	neutral	0,22	deleterious	1	deleterious	0,77	low_impact	-1,66	medium_impact	0,04	high_impact	2,19	0,44	0,8	47,71	9,69	P	0,62	P	0,56	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10853	10853	C	G	MI.16509	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	94	32	L	V	Cta/Gta	-0,4	0	0	possibly_damaging	0,9	neutral	0,07	neutral	1,46	neutral	-0,91	neutral	-1,78	medium_impact	3,23	neutral	0,63	damaging	0,17	deleterious	3,19	22,7	0,44	0,55	NA	NA	neutral	0,44	disease	0,6	neutral	0,42	2	neutral	0,97	neutral	0,09	NA	0	deleterious	0,74	low_impact	-1,61	medium_impact	-0,43	high_impact	2,07	0,24	0,8	18,95	18,03	N	0,43	N	0,4	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8462	8462	T	A	MI.1651	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	97	33	Y	N	Tac/Aac	-8,2	0	0	probably_damaging	1	neutral	0,34	neutral	1,56	deleterious	-4,01	deleterious	-7	low_impact	1,6	neutral	0,99	neutral	0,52	deleterious	4,18	23,8	0,4839256	0,85	disease	0,8	neutral	0,37	disease	0,71	neutral	0,28	4	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,83	low_impact	-3,6	medium_impact	0,13	medium_impact	0,27	0,25	0,85	NA	NA	N	0,46	N	0,71	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10853	10853	C	A	MI.16510	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	94	32	L	M	Cta/Ata	-0,4	0	0	probably_damaging	0,99	neutral	0,25	neutral	1,44	neutral	-1,17	neutral	-0,98	medium_impact	1,99	neutral	0,77	neutral	0,95	deleterious	2,37	18,59	0,29	0,45	NA	NA	neutral	0,21	neutral	0,38	neutral	0,2	6	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,7	low_impact	-2,59	medium_impact	-0,07	medium_impact	0,84	0,4	0,8	18,95	18,03	N	0,47	N	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10854	10854	T	G	MI.16511	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	95	32	L	R	cTa/cGa	-4,09	0	0	probably_damaging	0,99	deleterious	0,01	neutral	1,34	deleterious	-3,44	deleterious	-3,89	medium_impact	3,23	damaging	0,59	damaging	0,12	deleterious	3,93	23,5	0,1	0,4	NA	NA	disease	0,8	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,85	low_impact	-2,59	medium_impact	-0,92	high_impact	2,07	0,17	0,8	18,95	18,03	N	0,27	N	0,97	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10854	10854	T	C	MI.16512	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	95	32	L	P	cTa/cCa	-4,09	0	0	probably_damaging	1	deleterious	0	neutral	1,34	deleterious	-3,68	deleterious	-4,63	medium_impact	3,23	damaging	0,57	damaging	0,12	deleterious	3,68	23,3	0,1	0,4	NA	NA	disease	0,78	disease	0,73	disease	0,75	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,07	0,1	0,8	18,95	18,03	N	0,29	N	0,9	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10854	10854	T	A	MI.16513	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	95	32	L	Q	cTa/cAa	-4,09	0	0	probably_damaging	1	deleterious	0,02	neutral	1,34	deleterious	-3,58	deleterious	-3,86	medium_impact	3,23	neutral	0,65	damaging	0,17	deleterious	3,85	23,4	0,15	0,4	NA	NA	disease	0,64	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,54	medium_impact	-0,75	high_impact	2,07	0,14	0,8	18,95	18,03	N	0,31	N	0,93	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10856	10856	A	T	MI.16514	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	97	33	I	F	Att/Ttt	-9,62	0	0	possibly_damaging	0,51	neutral	0,64	neutral	1,49	neutral	-1	neutral	-1,67	low_impact	1,44	neutral	0,74	neutral	0,73	deleterious	2,44	19,06	0,12	0,4	NA	NA	neutral	0,48	neutral	0,4	neutral	0,31	4	neutral	0,43	deleterious	0,57	neutral	-3	deleterious	0,7	medium_impact	-0,73	medium_impact	0,34	medium_impact	0,3	0,34	0,8	22,88	20,34	N	0,32	N	0,49	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10856	10856	A	C	MI.16515	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	97	33	I	L	Att/Ctt	-9,62	0	0	benign	0,01	neutral	1	neutral	1,76	neutral	0,98	neutral	0,57	neutral_impact	-0,28	neutral	0,76	neutral	0,99	deleterious	0,81	9,53	0,22	0,45	NA	NA	neutral	0,1	neutral	0,29	neutral	0,18	6	neutral	0,01	deleterious	1	neutral	-6	deleterious	0,58	medium_impact	1,16	high_impact	1,88	low_impact	-1,4	0,28	0,8	22,88	20,34	N	0,33	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10856	10856	A	G	MI.16516	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	97	33	I	V	Att/Gtt	-9,62	0	0	benign	0,02	neutral	0,28	neutral	1,55	neutral	-0,3	neutral	-0,45	low_impact	1,44	neutral	0,78	neutral	0,84	neutral	1,65	14,14	0,31	0,45	NA	NA	neutral	0,17	neutral	0,4	neutral	0,23	5	neutral	0,71	deleterious	0,63	neutral	-6	deleterious	0,6	medium_impact	0,87	medium_impact	-0,03	medium_impact	0,3	0,42	0,8	22,88	20,34	N	0,45	N	0,55	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10857	10857	T	C	MI.16517	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	98	33	I	T	aTt/aCt	-9,62	0	0	benign	0,03	neutral	0,07	neutral	1,47	neutral	-1,31	neutral	-2,16	low_impact	1,09	neutral	0,79	neutral	0,85	deleterious	1,97	16,02	0,16	0,45	NA	NA	neutral	0,26	neutral	0,45	neutral	0,16	7	neutral	0,93	deleterious	0,52	neutral	-6	deleterious	0,68	medium_impact	0,7	medium_impact	-0,43	medium_impact	-0,05	0,24	0,8	22,88	20,34	N	0,43	N	0,14	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10857	10857	T	G	MI.16518	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	98	33	I	S	aTt/aGt	-9,62	0	0	benign	0,27	deleterious	0,02	neutral	1,48	neutral	-1,18	deleterious	-2,85	low_impact	1,17	neutral	0,73	neutral	0,8	deleterious	3,98	23,6	0,12	0,4	NA	NA	disease	0,55	disease	0,53	disease	0,56	1	neutral	0,98	neutral	0,38	neutral	-2	deleterious	0,73	medium_impact	-0,31	medium_impact	-0,75	medium_impact	0,03	0,26	0,8	22,88	20,34	N	0,38	N	0,64	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10857	10857	T	A	MI.16519	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	98	33	I	N	aTt/aAt	-9,62	0	0	possibly_damaging	0,59	deleterious	0	neutral	1,41	deleterious	-3,28	deleterious	-3,64	medium_impact	2,4	neutral	0,71	neutral	0,45	deleterious	4,28	24	0,17	0,45	NA	NA	disease	0,62	disease	0,62	disease	0,73	5	deleterious	1	neutral	0,21	deleterious	4	deleterious	0,74	medium_impact	-0,87	low_impact	-1,48	medium_impact	1,25	0,2	0,8	22,88	20,34	N	0,36	N	0,84	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8463	8463	A	G	MI.1652	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	98	33	Y	C	tAc/tGc	0,36	0	0	probably_damaging	1	neutral	0,18	neutral	1,55	deleterious	-4,48	deleterious	-6,96	medium_impact	2,69	neutral	1	neutral	0,4	deleterious	3,99	23,6	0,5577664	0,85	disease	0,9	neutral	0,34	disease	0,77	neutral	0,27	5	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	-0,08	medium_impact	1,21	0,11	0,85	NA	NA	N	0,53	P	0,65	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10858	10858	T	G	MI.16520	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	99	33	I	M	atT/atG	1,91	0,02	0	benign	0,05	neutral	0,43	neutral	1,49	neutral	-0,96	neutral	0,02	low_impact	1,21	neutral	0,78	neutral	0,98	neutral	1,79	14,91	0,31	0,45	NA	NA	neutral	0,16	neutral	0,36	neutral	0,23	5	neutral	0,53	deleterious	0,69	neutral	-6	deleterious	0,67	medium_impact	0,48	medium_impact	0,13	medium_impact	0,07	0,4	0,8	22,88	20,34	N	0,43	N	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10858	10858	T	A	MI.16521	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	99	33	I	M	atT/atA	1,91	0,02	0	benign	0,05	neutral	0,43	neutral	1,49	neutral	-0,96	neutral	0,02	low_impact	1,21	neutral	0,78	neutral	0,98	deleterious	2,11	16,95	0,31	0,45	NA	NA	neutral	0,16	neutral	0,36	neutral	0,23	5	neutral	0,53	deleterious	0,69	neutral	-6	deleterious	0,67	medium_impact	0,48	medium_impact	0,13	medium_impact	0,07	0,4	0,8	22,88	20,34	N	0,43	N	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10859	10859	A	T	MI.16522	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	100	34	I	F	Att/Ttt	-1,55	0	0	probably_damaging	1	neutral	0,06	neutral	1,36	neutral	-1,79	deleterious	-2,96	medium_impact	2,87	neutral	0,69	damaging	0,15	deleterious	3,51	23,1	0,12	0,4	NA	NA	disease	0,74	disease	0,61	disease	0,56	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,71	0,41	0,8	40,31	9,47	N	0,34	N	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10859	10859	A	G	MI.16523	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	100	34	I	V	Att/Gtt	-1,55	0	0	probably_damaging	1	neutral	0,08	neutral	1,42	neutral	-1,08	neutral	-0,71	medium_impact	3,07	neutral	0,79	neutral	0,72	neutral	1,76	14,75	0,42	0,55	NA	NA	neutral	0,3	neutral	0,47	neutral	0,16	7	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,66	low_impact	-3,54	medium_impact	-0,39	medium_impact	1,91	0,49	0,8	40,31	9,47	N	0,48	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10859	10859	A	C	MI.16524	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	100	34	I	L	Att/Ctt	-1,55	0	0	probably_damaging	1	neutral	0,51	neutral	1,63	neutral	0,21	neutral	-1,37	low_impact	1,75	neutral	0,76	neutral	0,32	deleterious	3,53	23,1	0,26	0,45	NA	NA	neutral	0,45	neutral	0,38	neutral	0,2	6	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,68	low_impact	-3,54	medium_impact	0,21	medium_impact	0,61	0,45	0,8	40,31	9,47	N	0,34	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10860	10860	T	C	MI.16525	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	101	34	I	T	aTt/aCt	3,75	0,99	0	probably_damaging	1	deleterious	0,04	neutral	1,34	neutral	-2,17	deleterious	-3,66	medium_impact	2,87	neutral	0,76	damaging	0,17	deleterious	3,08	22,5	0,18	0,45	NA	NA	disease	0,66	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,78	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,71	0,28	0,8	40,31	9,47	P	0,52	P	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10860	10860	T	A	MI.16526	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	101	34	I	N	aTt/aAt	3,75	0,99	0	probably_damaging	1	deleterious	0	neutral	1,29	deleterious	-3,57	deleterious	-5,2	medium_impact	3,07	neutral	0,63	damaging	0,14	deleterious	4,07	23,7	0,18	0,45	NA	NA	disease	0,77	disease	0,67	disease	0,7	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	medium_impact	1,91	0,15	0,8	40,31	9,47	N	0,5	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10860	10860	T	G	MI.16527	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	101	34	I	S	aTt/aGt	3,75	0,99	0	probably_damaging	1	neutral	0,07	neutral	1,31	neutral	-2,84	deleterious	-4,44	medium_impact	3,42	neutral	0,71	damaging	0,16	deleterious	3,99	23,6	0,12	0,4	NA	NA	disease	0,78	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,43	high_impact	2,26	0,21	0,8	40,31	9,47	P	0,55	P	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10861	10861	T	G	MI.16528	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	102	34	I	M	atT/atG	7,44	1	0	probably_damaging	1	neutral	0,14	neutral	1,35	neutral	-1,91	neutral	-2,14	medium_impact	3,07	neutral	0,78	damaging	0,17	deleterious	3,2	22,7	0,32	0,5	NA	NA	disease	0,51	neutral	0,46	neutral	0,44	1	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	-0,24	medium_impact	1,91	0,38	0,8	40,31	9,47	P	0,6	P	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10861	10861	T	A	MI.16529	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	102	34	I	M	atT/atA	7,44	1	0	probably_damaging	1	neutral	0,14	neutral	1,35	neutral	-1,91	neutral	-2,14	medium_impact	3,07	neutral	0,78	damaging	0,17	deleterious	3,58	23,2	0,32	0,5	NA	NA	disease	0,51	neutral	0,46	neutral	0,44	1	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	-0,24	medium_impact	1,91	0,38	0,8	40,31	9,47	P	0,6	P	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8463	8463	A	C	MI.1653	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	98	33	Y	S	tAc/tCc	0,36	0	0	probably_damaging	0,99	neutral	0,44	neutral	1,61	deleterious	-3,07	deleterious	-6,8	neutral_impact	0,68	neutral	0,99	neutral	0,85	deleterious	4,1	23,7	0,42207444	0,85	disease	0,78	neutral	0,33	disease	0,65	neutral	0,22	6	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,82	low_impact	-2,65	medium_impact	0,23	medium_impact	-0,52	0,29	0,85	NA	NA	N	0,49	N	0,64	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10862	10862	A	C	MI.16530	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	103	35	S	R	Agc/Cgc	-6,16	0	0	probably_damaging	1	neutral	0,24	neutral	1,47	neutral	-2,37	deleterious	-2,65	medium_impact	3,02	neutral	0,63	neutral	0,44	deleterious	3,59	23,2	0,21	0,45	NA	NA	disease	0,83	disease	0,7	disease	0,78	6	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,08	medium_impact	1,86	0,28	0,8	15,9	10,58	N	0,36	N	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10862	10862	A	T	MI.16531	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	103	35	S	C	Agc/Tgc	-6,16	0	0	probably_damaging	1	neutral	0,12	neutral	1,46	deleterious	-3,01	neutral	-2,27	medium_impact	3,02	neutral	0,76	neutral	0,6	deleterious	3,12	22,6	0,17	0,45	NA	NA	disease	0,7	neutral	0,5	disease	0,54	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,28	medium_impact	1,86	0,2	0,8	15,9	10,58	N	0,4	N	0,53	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10862	10862	A	G	MI.16532	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	103	35	S	G	Agc/Ggc	-6,16	0	0	probably_damaging	1	neutral	0,27	neutral	1,49	neutral	-1,61	neutral	-1,98	medium_impact	2,68	neutral	0,78	neutral	0,7	deleterious	3,3	22,9	0,3	0,45	NA	NA	neutral	0,48	disease	0,54	neutral	0,45	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	-0,04	medium_impact	1,53	0,43	0,8	15,9	10,58	N	0,4	N	0,51	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10863	10863	G	T	MI.16533	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	104	35	S	I	aGc/aTc	0,75	0	0	probably_damaging	1	neutral	0,41	neutral	1,59	neutral	0,09	deleterious	-3,07	low_impact	1,88	neutral	0,64	neutral	0,63	deleterious	3,9	23,5	0,19	0,45	NA	NA	disease	0,77	disease	0,58	disease	0,71	4	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,79	low_impact	-3,54	medium_impact	0,11	medium_impact	0,73	0,28	0,8	15,9	10,58	N	0,33	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10863	10863	G	C	MI.16534	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	104	35	S	T	aGc/aCc	0,75	0	0	probably_damaging	1	neutral	0,34	neutral	1,53	neutral	-0,64	neutral	-1,32	medium_impact	2,48	neutral	0,74	neutral	0,93	deleterious	3,09	22,5	0,32	0,5	NA	NA	neutral	0,37	neutral	0,38	neutral	0,17	7	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	0,04	medium_impact	1,33	0,49	0,8	15,9	10,58	N	0,47	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10863	10863	G	A	MI.16535	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	104	35	S	N	aGc/aAc	0,75	0	0	probably_damaging	1	neutral	0,22	neutral	1,46	neutral	-2,6	neutral	-2	low_impact	1,48	neutral	0,73	neutral	0,86	deleterious	2,28	18,05	0,52	0,6	NA	NA	disease	0,59	disease	0,58	disease	0,65	3	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	-0,11	medium_impact	0,34	0,41	0,8	15,9	10,58	N	0,39	N	0,52	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10865	10865	A	G	MI.16536	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	106	36	I	V	Atc/Gtc	-1,55	0	0	benign	0,05	neutral	0,16	neutral	1,63	neutral	0,33	neutral	-0,45	neutral_impact	0,34	neutral	0,77	neutral	0,82	neutral	-0,17	1,25	0,33	0,5	NA	NA	neutral	0,11	neutral	0,32	neutral	0,25	5	neutral	0,83	deleterious	0,56	neutral	-6	neutral	0,1	medium_impact	0,48	medium_impact	-0,2	medium_impact	-0,79	0,32	0,8	27,02	18,08	N	0,43	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10865	10865	A	T	MI.16537	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	106	36	I	F	Atc/Ttc	-1,55	0	0	benign	0,01	neutral	0,54	neutral	1,57	neutral	-0,18	neutral	-0,93	neutral_impact	-0,14	neutral	0,74	neutral	0,98	deleterious	0,33	5,97	0,13	0,4	NA	NA	neutral	0,28	neutral	0,27	neutral	0,16	7	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,12	medium_impact	1,16	medium_impact	0,24	low_impact	-1,26	0,4	0,8	27,02	18,08	N	0,37	N	0,1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10865	10865	A	C	MI.16538	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	106	36	I	L	Atc/Ctc	-1,55	0	0	benign	0	neutral	1	neutral	1,72	neutral	0,86	neutral	0,79	neutral_impact	-1,88	neutral	0,78	neutral	0,98	neutral	-1,06	0,01	0,24	0,45	NA	NA	neutral	0,07	neutral	0,23	neutral	0,18	6	neutral	0	deleterious	1	neutral	-6	neutral	0,07	high_impact	2,1	high_impact	1,88	low_impact	-2,99	0,37	0,8	27,02	18,08	N	0,3	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10866	10866	T	C	MI.16539	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	107	36	I	T	aTc/aCc	-10,08	0	0	benign	0,11	neutral	0,36	neutral	1,5	neutral	-0,93	neutral	-1,29	neutral_impact	0,09	neutral	0,76	neutral	0,93	deleterious	-0,02	2,38	0,21	0,45	NA	NA	neutral	0,12	neutral	0,3	neutral	0,24	5	neutral	0,58	deleterious	0,63	neutral	-6	neutral	0,11	medium_impact	0,14	medium_impact	0,06	low_impact	-1,04	0,17	0,8	27,02	18,08	N	0,45	N	0	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8463	8463	A	T	MI.1654	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	98	33	Y	F	tAc/tTc	0,36	0	0	probably_damaging	0,97	neutral	0,73	neutral	1,6	neutral	-0,8	neutral	-1,42	neutral_impact	-0,37	neutral	0,99	neutral	0,96	deleterious	2,16	17,23	0,51274914	0,85	neutral	0,19	neutral	0,09	neutral	0,41	neutral	0,04	9	neutral	0,97	neutral	0,38	neutral	-2	deleterious	0,7	low_impact	-2,19	medium_impact	0,54	low_impact	-1,42	0,29	0,85	NA	NA	N	0,43	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10866	10866	T	G	MI.16540	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	107	36	I	S	aTc/aGc	-10,08	0	0	benign	0,01	neutral	0,32	neutral	1,48	neutral	-1,3	neutral	-1,67	neutral_impact	-0,2	neutral	0,68	neutral	0,85	neutral	0,99	10,59	0,08	0,35	NA	NA	neutral	0,34	neutral	0,33	neutral	0,13	7	neutral	0,67	deleterious	0,66	neutral	-6	neutral	0,13	medium_impact	1,16	medium_impact	0,02	low_impact	-1,32	0,24	0,8	27,02	18,08	N	0,43	N	0,03	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10866	10866	T	A	MI.16541	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	107	36	I	N	aTc/aAc	-10,08	0	0	benign	0,17	neutral	0,09	neutral	1,43	neutral	-2,86	deleterious	-2,64	low_impact	1,24	neutral	0,74	neutral	0,49	deleterious	2,29	18,08	0,14	0,4	NA	NA	neutral	0,46	disease	0,54	neutral	0,41	2	neutral	0,9	neutral	0,46	neutral	-6	neutral	0,17	medium_impact	-0,07	medium_impact	-0,36	medium_impact	0,1	0,2	0,8	27,02	18,08	N	0,43	N	0,21	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10867	10867	C	G	MI.16542	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	108	36	I	M	atC/atG	-0,17	0	0	benign	0,26	neutral	0,25	neutral	1,48	neutral	-1,34	neutral	0,06	neutral_impact	0,34	neutral	0,77	neutral	0,96	deleterious	0,2	4,66	0,3	0,45	NA	NA	neutral	0,12	neutral	0,28	neutral	0,24	5	neutral	0,7	deleterious	0,5	neutral	-6	neutral	0,34	medium_impact	-0,29	medium_impact	-0,07	medium_impact	-0,79	0,4	0,8	27,02	18,08	N	0,46	N	0,03	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10867	10867	C	A	MI.16543	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	108	36	I	M	atC/atA	-0,17	0	0	benign	0,26	neutral	0,25	neutral	1,48	neutral	-1,34	neutral	0,06	neutral_impact	0,34	neutral	0,77	neutral	0,96	deleterious	0,72	8,98	0,3	0,45	NA	NA	neutral	0,12	neutral	0,28	neutral	0,24	5	neutral	0,7	deleterious	0,5	neutral	-6	neutral	0,34	medium_impact	-0,29	medium_impact	-0,07	medium_impact	-0,79	0,4	0,8	27,02	18,08	N	0,46	N	0,03	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10868	10868	A	T	MI.16544	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	109	37	I	F	Atc/Ttc	-9,16	0	0	benign	0,17	neutral	1	neutral	1,49	neutral	-0,93	neutral	-1,72	low_impact	1,81	neutral	0,73	neutral	0,42	deleterious	2,22	17,62	0,14	0,4	NA	NA	neutral	0,39	neutral	0,32	neutral	0,16	7	neutral	0,17	deleterious	0,92	neutral	-6	deleterious	0,7	medium_impact	-0,07	high_impact	1,88	medium_impact	0,67	0,51	0,8	22,88	19,35	N	0,23	N	0,44	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10868	10868	A	G	MI.16545	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	109	37	I	V	Atc/Gtc	-9,16	0	0	possibly_damaging	0,73	neutral	0,21	neutral	1,55	neutral	-0,27	neutral	-0,25	low_impact	1,71	neutral	0,74	neutral	0,93	neutral	1,49	13,26	0,28	0,45	NA	NA	neutral	0,12	neutral	0,33	neutral	0,25	5	neutral	0,84	neutral	0,24	neutral	-3	deleterious	0,61	low_impact	-1,12	medium_impact	-0,12	medium_impact	0,57	0,55	0,8	22,88	19,35	N	0,48	N	0,63	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10868	10868	A	C	MI.16546	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	109	37	I	L	Atc/Ctc	-9,16	0	0	possibly_damaging	0,73	neutral	0,83	neutral	1,76	neutral	1,01	neutral	-0,6	neutral_impact	0,73	neutral	0,72	neutral	0,94	neutral	1,7	14,39	0,19	0,45	NA	NA	neutral	0,13	neutral	0,21	neutral	0,22	6	neutral	0,68	deleterious	0,55	neutral	-3	deleterious	0,59	low_impact	-1,12	medium_impact	0,59	medium_impact	-0,4	0,48	0,8	22,88	19,35	N	0,38	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10869	10869	T	A	MI.16547	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	110	37	I	N	aTc/aAc	-2,24	0	0	probably_damaging	0,98	neutral	0,15	neutral	1,41	deleterious	-3,25	deleterious	-3,18	medium_impact	2,91	neutral	0,69	damaging	0,21	deleterious	4,24	23,9	0,16	0,45	NA	NA	disease	0,53	disease	0,57	disease	0,7	4	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,73	low_impact	-2,31	medium_impact	-0,22	medium_impact	1,75	0,18	0,8	22,88	19,35	N	0,33	N	0,74	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10869	10869	T	C	MI.16548	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	110	37	I	T	aTc/aCc	-2,24	0	0	probably_damaging	0,95	neutral	0,28	neutral	1,47	neutral	-1,23	neutral	-1,22	low_impact	1,32	neutral	0,73	neutral	0,97	neutral	1,65	14,11	0,18	0,45	NA	NA	neutral	0,24	neutral	0,36	neutral	0,17	7	neutral	0,96	neutral	0,17	neutral	-2	deleterious	0,68	low_impact	-1,92	medium_impact	-0,03	medium_impact	0,18	0,24	0,8	22,88	19,35	N	0,45	N	0,08	polymorphism	1	0,04	.	.	.	.	.	.	COSM1132244	.	.	.	.	.	.	.	.
chrM	10869	10869	T	G	MI.16549	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	110	37	I	S	aTc/aGc	-2,24	0	0	probably_damaging	0,97	neutral	0,35	neutral	1,45	neutral	-1,74	neutral	-2,29	medium_impact	2,36	neutral	0,8	neutral	0,84	deleterious	2,98	22,2	0,09	0,35	NA	NA	neutral	0,49	neutral	0,46	neutral	0,46	1	neutral	0,97	neutral	0,19	deleterious	1	deleterious	0,73	low_impact	-2,14	medium_impact	0,05	medium_impact	1,21	0,26	0,8	22,88	19,35	N	0,36	N	0,31	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8465	8465	C	A	MI.1655	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	100	34	H	N	Cac/Aac	-2,19	0	0	probably_damaging	0,96	neutral	0,39	neutral	0,72	deleterious	-6,39	deleterious	-3,33	medium_impact	1,96	neutral	0,99	neutral	0,66	deleterious	2,66	20,5	0,74096869	0,85	neutral	0,35	neutral	0,18	neutral	0,48	neutral	0,12	8	neutral	0,96	neutral	0,22	deleterious	1	deleterious	0,64	low_impact	-2,07	medium_impact	0,18	medium_impact	0,58	0,58	0,85	10,29	8,62	N	0,51	P	0,48	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10870	10870	C	A	MI.16550	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	111	37	I	M	atC/atA	-0,17	0	0	probably_damaging	0,98	neutral	0,44	neutral	1,49	neutral	-1,03	neutral	-1,09	low_impact	1,71	neutral	0,72	neutral	0,88	deleterious	2,37	18,66	0,3	0,45	NA	NA	neutral	0,15	neutral	0,3	neutral	0,24	5	neutral	0,98	neutral	0,23	neutral	-2	deleterious	0,67	low_impact	-2,31	medium_impact	0,14	medium_impact	0,57	0,55	0,8	22,88	19,35	N	0,45	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10870	10870	C	G	MI.16551	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	111	37	I	M	atC/atG	-0,17	0	0	probably_damaging	0,98	neutral	0,44	neutral	1,49	neutral	-1,03	neutral	-1,09	low_impact	1,71	neutral	0,72	neutral	0,88	deleterious	1,93	15,79	0,3	0,45	NA	NA	neutral	0,15	neutral	0,3	neutral	0,24	5	neutral	0,98	neutral	0,23	neutral	-2	deleterious	0,67	low_impact	-2,31	medium_impact	0,14	medium_impact	0,57	0,55	0,8	22,88	19,35	N	0,45	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10871	10871	C	G	MI.16552	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	112	38	P	A	Cct/Gct	-8,93	0	0	possibly_damaging	0,62	neutral	0,44	neutral	1,67	neutral	2,16	neutral	1,16	neutral_impact	0,6	neutral	0,78	neutral	0,86	deleterious	2,79	21,3	0,23	0,45	NA	NA	neutral	0,11	neutral	0,25	neutral	0,26	5	neutral	0,63	neutral	0,41	neutral	-3	deleterious	0,7	medium_impact	-0,92	medium_impact	0,14	medium_impact	-0,53	0,66	0,8	28,76	30,68	N	0,36	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10871	10871	C	T	MI.16553	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	112	38	P	S	Cct/Tct	-8,93	0	0	benign	0,18	neutral	1	neutral	1,98	neutral	4,21	neutral	2,72	neutral_impact	-1,49	neutral	0,7	neutral	0,95	neutral	0,95	10,38	0,23	0,45	NA	NA	neutral	0,06	neutral	0,16	neutral	0,22	6	neutral	0,18	deleterious	0,91	neutral	-6	deleterious	0,67	medium_impact	-0,1	high_impact	1,88	low_impact	-2,6	0,15	0,8	28,76	30,68	N	0,37	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10871	10871	C	A	MI.16554	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	112	38	P	T	Cct/Act	-8,93	0	0	benign	0,18	neutral	0,35	neutral	1,67	neutral	2,17	neutral	1,41	neutral_impact	-0,34	neutral	0,76	neutral	0,9	deleterious	2,36	18,57	0,21	0,45	NA	NA	neutral	0,16	neutral	0,24	neutral	0,23	5	neutral	0,58	deleterious	0,59	neutral	-6	deleterious	0,7	medium_impact	-0,1	medium_impact	0,05	low_impact	-1,46	0,66	0,8	28,76	30,68	N	0,41	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10872	10872	C	G	MI.16555	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	113	38	P	R	cCt/cGt	0,75	0	0	probably_damaging	0,95	neutral	0,29	neutral	1,59	neutral	0,35	neutral	-0,37	low_impact	1,5	neutral	0,73	damaging	0,23	deleterious	3,39	23	0,09	0,35	NA	NA	disease	0,55	disease	0,63	disease	0,71	4	neutral	0,96	neutral	0,17	neutral	-2	deleterious	0,79	low_impact	-1,92	medium_impact	-0,02	medium_impact	0,36	0,48	0,8	28,76	30,68	N	0,36	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10872	10872	C	T	MI.16556	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	113	38	P	L	cCt/cTt	0,75	0	0	possibly_damaging	0,82	neutral	0,63	neutral	1,67	neutral	2,17	neutral	-0,76	low_impact	1,5	neutral	0,68	neutral	0,29	deleterious	4,11	23,7	0,15	0,4	NA	NA	neutral	0,32	neutral	0,35	neutral	0,15	7	neutral	0,79	neutral	0,41	neutral	-3	deleterious	0,73	low_impact	-1,34	medium_impact	0,33	medium_impact	0,36	0,58	0,8	28,76	30,68	N	0,36	N	0,82	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10872	10872	C	A	MI.16557	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	113	38	P	H	cCt/cAt	0,75	0	0	probably_damaging	0,98	neutral	0,43	neutral	1,58	neutral	-0,37	neutral	-0,46	low_impact	1,5	neutral	0,75	damaging	0,27	deleterious	3,71	23,3	0,13	0,4	NA	NA	neutral	0,29	disease	0,6	neutral	0,37	3	deleterious	0,98	neutral	0,23	neutral	-2	deleterious	0,74	low_impact	-2,31	medium_impact	0,13	medium_impact	0,36	0,4	0,8	28,76	30,68	N	0,36	N	0,79	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10874	10874	C	A	MI.16558	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	115	39	L	M	Cta/Ata	-0,63	0	0	probably_damaging	0,96	neutral	0,27	neutral	1,23	neutral	-2,9	neutral	-1,21	medium_impact	2,3	neutral	0,79	neutral	0,74	deleterious	3,51	23,1	0,31	0,45	NA	NA	neutral	0,33	neutral	0,46	neutral	0,17	7	neutral	0,96	neutral	0,16	deleterious	1	deleterious	0,73	low_impact	-2,01	medium_impact	-0,04	medium_impact	1,15	0,56	0,8	8,71	10,96	N	0,4	N	0,9	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10874	10874	C	G	MI.16559	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	115	39	L	V	Cta/Gta	-0,63	0	0	possibly_damaging	0,52	neutral	0,08	neutral	1,3	neutral	-1,75	neutral	-1,94	medium_impact	2,79	neutral	0,79	neutral	0,57	deleterious	3,18	22,7	0,32	0,5	NA	NA	neutral	0,45	disease	0,6	neutral	0,41	2	neutral	0,91	neutral	0,28	NA	0	deleterious	0,76	medium_impact	-0,75	medium_impact	-0,39	medium_impact	1,63	0,42	0,8	8,71	10,96	N	0,43	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8465	8465	C	T	MI.1656	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	100	34	H	Y	Cac/Tac	-2,19	0	0	probably_damaging	0,96	neutral	1	neutral	0,97	neutral	-2,06	neutral	-0,77	neutral_impact	0,22	neutral	1	neutral	0,96	deleterious	0,87	9,91	0,66348541	0,85	neutral	0,25	neutral	0,07	neutral	0,32	neutral	0,04	9	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,63	low_impact	-2,07	high_impact	1,98	medium_impact	-0,91	0,26	0,85	10,29	8,62	N	0,36	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10875	10875	T	G	MI.16560	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	116	39	L	R	cTa/cGa	-1,78	0	0	probably_damaging	0,98	deleterious	0,01	neutral	1,19	deleterious	-4,23	deleterious	-4,26	medium_impact	3,34	damaging	0,56	neutral	0,34	deleterious	3,87	23,5	0,06	0,35	NA	NA	disease	0,8	disease	0,79	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,88	low_impact	-2,31	medium_impact	-0,92	high_impact	2,18	0,18	0,8	8,71	10,96	N	0,4	N	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10875	10875	T	C	MI.16561	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	116	39	L	P	cTa/cCa	-1,78	0	0	probably_damaging	0,98	deleterious	0,04	neutral	1,18	deleterious	-4,81	deleterious	-4,89	medium_impact	3,34	damaging	0,53	neutral	0,31	deleterious	3,62	23,2	0,05	0,35	NA	NA	disease	0,76	disease	0,78	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,88	low_impact	-2,31	medium_impact	-0,57	high_impact	2,18	0,15	0,8	8,71	10,96	N	0,42	N	0,98	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10875	10875	T	A	MI.16562	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	116	39	L	Q	cTa/cAa	-1,78	0	0	probably_damaging	0,98	deleterious	0,01	neutral	1,19	deleterious	-4,39	deleterious	-4,21	medium_impact	3,34	neutral	0,65	neutral	0,41	deleterious	3,78	23,4	0,1	0,4	NA	NA	disease	0,71	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-2,31	medium_impact	-0,92	high_impact	2,18	0,13	0,8	8,71	10,96	N	0,36	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10877	10877	C	A	MI.16563	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	118	40	L	M	Cta/Ata	-4,78	0	0	benign	0,12	neutral	0,38	neutral	1,43	neutral	-1,32	neutral	-0,12	neutral_impact	0,68	neutral	0,76	neutral	0,94	deleterious	1,93	15,76	0,28	0,45	NA	NA	neutral	0,09	neutral	0,36	neutral	0,26	5	neutral	0,56	deleterious	0,63	neutral	-6	deleterious	0,68	medium_impact	0,1	medium_impact	0,08	medium_impact	-0,45	0,57	0,8	23,75	22,06	N	0,41	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10877	10877	C	G	MI.16564	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	118	40	L	V	Cta/Gta	-4,78	0	0	benign	0,03	neutral	0,54	neutral	1,48	neutral	-0,8	neutral	-0,58	low_impact	1,15	neutral	0,79	neutral	0,83	neutral	1,32	12,36	0,3	0,45	NA	NA	neutral	0,18	neutral	0,45	neutral	0,22	6	neutral	0,43	deleterious	0,76	neutral	-6	deleterious	0,7	medium_impact	0,7	medium_impact	0,24	medium_impact	0,01	0,64	0,8	23,75	22,06	N	0,29	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10878	10878	T	G	MI.16565	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	119	40	L	R	cTa/cGa	-7,09	0	0	possibly_damaging	0,78	neutral	0,35	neutral	1,35	deleterious	-3,26	neutral	-1,59	medium_impact	2,12	neutral	0,71	neutral	0,49	deleterious	2,38	18,71	0,04	0,35	NA	NA	disease	0,61	disease	0,64	disease	0,73	5	neutral	0,8	neutral	0,29	NA	0	deleterious	0,79	low_impact	-1,23	medium_impact	0,05	medium_impact	0,97	0,21	0,8	23,75	22,06	N	0,33	N	0,58	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10878	10878	T	A	MI.16566	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	119	40	L	Q	cTa/cAa	-7,09	0	0	possibly_damaging	0,83	neutral	0,39	neutral	1,37	neutral	-2,51	neutral	-1,33	low_impact	1,02	neutral	0,75	neutral	0,8	deleterious	2,54	19,69	0,06	0,35	NA	NA	neutral	0,25	neutral	0,38	neutral	0,15	7	neutral	0,83	neutral	0,28	neutral	-3	deleterious	0,7	low_impact	-1,37	medium_impact	0,09	medium_impact	-0,12	0,23	0,8	23,75	22,06	N	0,39	N	0,49	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10878	10878	T	C	MI.16567	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	119	40	L	P	cTa/cCa	-7,09	0	0	probably_damaging	0,93	neutral	0,25	neutral	1,35	deleterious	-3,18	neutral	-1,22	low_impact	1,23	neutral	0,76	neutral	0,97	deleterious	2,21	17,55	0,04	0,35	NA	NA	disease	0,6	disease	0,59	neutral	0,48	0	neutral	0,95	neutral	0,16	neutral	-2	deleterious	0,79	low_impact	-1,77	medium_impact	-0,07	medium_impact	0,09	0,23	0,8	23,75	22,06	N	0,36	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10880	10880	T	C	MI.16568	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	121	41	F	L	Ttt/Ctt	-10,78	0	0	benign	0,05	neutral	0,83	neutral	1,8	neutral	1,7	neutral	-0,16	neutral_impact	-0,1	neutral	0,74	neutral	0,98	neutral	1,67	14,23	0,21	0,45	NA	NA	neutral	0,21	neutral	0,3	neutral	0,18	6	neutral	0,08	deleterious	0,89	neutral	-6	deleterious	0,69	medium_impact	0,48	medium_impact	0,59	low_impact	-1,23	0,47	0,8	27,23	22,95	N	0,36	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10880	10880	T	G	MI.16569	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	121	41	F	V	Ttt/Gtt	-10,78	0	0	possibly_damaging	0,54	neutral	0,31	neutral	1,64	neutral	0,61	neutral	-1,04	low_impact	1,38	neutral	0,72	neutral	0,76	deleterious	3,68	23,3	0,15	0,45	NA	NA	neutral	0,46	neutral	0,46	neutral	0,25	5	neutral	0,68	neutral	0,39	neutral	-3	deleterious	0,73	medium_impact	-0,78	medium_impact	0,01	medium_impact	0,24	0,38	0,8	27,23	22,95	N	0,45	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8465	8465	C	G	MI.1657	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	100	34	H	D	Cac/Gac	-2,19	0	0	probably_damaging	0,97	neutral	0,2	neutral	0,71	deleterious	-7,1	deleterious	-3,97	medium_impact	2,5	neutral	1	neutral	0,47	deleterious	2,57	19,92	0,41328743	0,85	neutral	0,34	neutral	0,22	disease	0,54	neutral	0,14	7	deleterious	0,98	neutral	0,12	deleterious	1	deleterious	0,68	low_impact	-2,19	medium_impact	-0,05	medium_impact	1,05	0,63	0,85	10,29	8,62	P	0,57	P	0,62	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10880	10880	T	A	MI.16570	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	121	41	F	I	Ttt/Att	-10,78	0	0	possibly_damaging	0,66	neutral	0,46	neutral	1,66	neutral	0,79	neutral	-0,85	low_impact	1,16	neutral	0,8	neutral	0,9	deleterious	4,07	23,7	0,18	0,45	NA	NA	neutral	0,44	neutral	0,45	neutral	0,21	6	neutral	0,65	neutral	0,4	neutral	-3	deleterious	0,75	medium_impact	-0,99	medium_impact	0,16	medium_impact	0,02	0,41	0,8	27,23	22,95	N	0,39	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10881	10881	T	C	MI.16571	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	122	41	F	S	tTt/tCt	-0,86	0	0	benign	0,09	neutral	0,44	neutral	1,56	neutral	-0,33	neutral	-1,79	low_impact	1,5	neutral	0,77	neutral	0,73	deleterious	4,07	23,7	0,06	0,35	NA	NA	neutral	0,39	neutral	0,41	neutral	0,15	7	neutral	0,5	deleterious	0,68	neutral	-6	deleterious	0,75	medium_impact	0,23	medium_impact	0,14	medium_impact	0,36	0,24	0,8	27,23	22,95	N	0,35	N	0,61	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10881	10881	T	G	MI.16572	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	122	41	F	C	tTt/tGt	-0,86	0	0	probably_damaging	0,98	neutral	0,1	neutral	1,51	neutral	-1,98	neutral	-1,71	medium_impact	2,19	neutral	0,75	neutral	0,48	deleterious	3,87	23,5	0,09	0,35	NA	NA	disease	0,56	disease	0,51	disease	0,53	1	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,76	low_impact	-2,31	medium_impact	-0,33	medium_impact	1,04	0,23	0,8	27,23	22,95	N	0,42	N	0,64	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10881	10881	T	A	MI.16573	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	122	41	F	Y	tTt/tAt	-0,86	0	0	possibly_damaging	0,84	neutral	0,72	neutral	1,53	neutral	-1,24	neutral	0,03	low_impact	1,5	neutral	0,78	neutral	0,99	deleterious	3,02	22,3	0,18	0,45	NA	NA	neutral	0,29	neutral	0,36	neutral	0,15	7	neutral	0,8	neutral	0,44	neutral	-3	deleterious	0,73	low_impact	-1,39	medium_impact	0,43	medium_impact	0,36	0,49	0,8	27,23	22,95	N	0,37	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10882	10882	T	A	MI.16574	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	123	41	F	L	ttT/ttA	-0,63	0	0	benign	0,05	neutral	0,83	neutral	1,8	neutral	1,7	neutral	-0,16	neutral_impact	-0,1	neutral	0,74	neutral	0,98	deleterious	2,13	17,05	0,21	0,45	NA	NA	neutral	0,21	neutral	0,3	neutral	0,18	6	neutral	0,08	deleterious	0,89	neutral	-6	deleterious	0,69	medium_impact	0,48	medium_impact	0,59	low_impact	-1,23	0,47	0,8	27,23	22,95	N	0,37	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10882	10882	T	G	MI.16575	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	123	41	F	L	ttT/ttG	-0,63	0	0	benign	0,05	neutral	0,83	neutral	1,8	neutral	1,7	neutral	-0,16	neutral_impact	-0,1	neutral	0,74	neutral	0,98	deleterious	1,94	15,81	0,21	0,45	NA	NA	neutral	0,21	neutral	0,3	neutral	0,18	6	neutral	0,08	deleterious	0,89	neutral	-6	deleterious	0,69	medium_impact	0,48	medium_impact	0,59	low_impact	-1,23	0,47	0,8	27,23	22,95	N	0,37	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10883	10883	T	G	MI.16576	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	124	42	F	V	Ttt/Gtt	-5,7	0	0	benign	0,25	neutral	0,08	neutral	1,56	neutral	-0,23	neutral	-0,18	low_impact	1,92	neutral	0,72	neutral	0,74	neutral	1,76	14,76	0,19	0,45	NA	NA	disease	0,53	disease	0,55	disease	0,6	2	neutral	0,91	neutral	0,42	neutral	-6	neutral	0,18	medium_impact	-0,27	medium_impact	-0,39	medium_impact	0,77	0,43	0,8	23,09	29,17	N	0,43	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10883	10883	T	C	MI.16577	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	124	42	F	L	Ttt/Ctt	-5,7	0	0	benign	0,01	neutral	1	neutral	1,81	neutral	1,31	neutral	1,36	neutral_impact	-0,88	neutral	0,74	neutral	0,98	neutral	-0,95	0,02	0,25	0,45	NA	NA	neutral	0,1	neutral	0,31	neutral	0,19	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,1	medium_impact	1,16	high_impact	1,88	low_impact	-2	0,57	0,8	23,09	29,17	N	0,31	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10883	10883	T	A	MI.16578	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	124	42	F	I	Ttt/Att	-5,7	0	0	benign	0,17	neutral	0,11	neutral	1,58	neutral	-0,05	neutral	0,48	low_impact	1,72	neutral	0,75	neutral	0,94	neutral	1,03	10,83	0,14	0,4	NA	NA	neutral	0,49	neutral	0,43	neutral	0,44	1	neutral	0,87	deleterious	0,47	neutral	-6	neutral	0,19	medium_impact	-0,07	medium_impact	-0,31	medium_impact	0,58	0,52	0,8	23,09	29,17	N	0,51	P	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10884	10884	T	A	MI.16579	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	125	42	F	Y	tTt/tAt	-1,55	0	0	possibly_damaging	0,6	neutral	0,07	neutral	1,45	neutral	-2,11	neutral	-0,88	medium_impact	2,27	neutral	0,73	neutral	0,78	deleterious	2,14	17,09	0,21	0,45	NA	NA	neutral	0,4	disease	0,51	neutral	0,22	6	neutral	0,93	neutral	0,24	NA	0	neutral	0,3	medium_impact	-0,88	medium_impact	-0,43	medium_impact	1,12	0,59	0,8	23,09	29,17	P	0,51	P	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8466	8466	A	T	MI.1658	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	101	34	H	L	cAc/cTc	-0,57	0	0	probably_damaging	0,97	neutral	0,68	neutral	0,74	deleterious	-5,06	deleterious	-4,4	low_impact	1	neutral	1	neutral	0,71	deleterious	2,73	21	0,59410459	0,85	neutral	0,32	neutral	0,22	neutral	0,46	neutral	0,13	7	neutral	0,97	neutral	0,36	neutral	-2	deleterious	0,68	low_impact	-2,19	medium_impact	0,48	medium_impact	-0,24	0,33	0,85	10,29	8,62	N	0,38	N	0,66	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10884	10884	T	C	MI.16580	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	125	42	F	S	tTt/tCt	-1,55	0	0	benign	0,03	neutral	0,05	neutral	1,48	neutral	-1,48	neutral	-2,14	low_impact	1,57	neutral	0,74	neutral	0,7	deleterious	2,15	17,16	0,06	0,35	NA	NA	disease	0,51	disease	0,56	disease	0,6	2	neutral	0,95	deleterious	0,51	neutral	-6	neutral	0,37	medium_impact	0,7	medium_impact	-0,52	medium_impact	0,43	0,19	0,8	23,09	29,17	N	0,44	N	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10884	10884	T	G	MI.16581	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	125	42	F	C	tTt/tGt	-1,55	0	0	probably_damaging	0,92	deleterious	0,03	neutral	1,43	deleterious	-3,16	neutral	-1,67	medium_impact	2,27	neutral	0,67	neutral	0,45	deleterious	3,6	23,2	0,09	0,35	NA	NA	disease	0,65	disease	0,58	disease	0,72	4	deleterious	0,99	neutral	0,06	deleterious	5	deleterious	0,65	low_impact	-1,71	medium_impact	-0,64	medium_impact	1,12	0,19	0,8	23,09	29,17	N	0,37	N	0,63	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10885	10885	T	G	MI.16582	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	126	42	F	L	ttT/ttG	7,44	0,96	0	benign	0,01	neutral	1	neutral	1,81	neutral	1,31	neutral	1,36	neutral_impact	-0,88	neutral	0,74	neutral	0,98	neutral	-0,6	0,13	0,25	0,45	NA	NA	neutral	0,1	neutral	0,31	neutral	0,19	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,1	medium_impact	1,16	high_impact	1,88	low_impact	-2	0,57	0,8	23,09	29,17	N	0,51	P	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10885	10885	T	A	MI.16583	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	126	42	F	L	ttT/ttA	7,44	0,96	0	benign	0,01	neutral	1	neutral	1,81	neutral	1,31	neutral	1,36	neutral_impact	-0,88	neutral	0,74	neutral	0,98	neutral	-0,49	0,24	0,25	0,45	NA	NA	neutral	0,1	neutral	0,31	neutral	0,19	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,1	medium_impact	1,16	high_impact	1,88	low_impact	-2	0,57	0,8	23,09	29,17	N	0,52	P	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10886	10886	A	G	MI.16584	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	127	43	N	D	Aac/Gac	-7,55	0	0	benign	0,36	neutral	0,2	neutral	1,46	neutral	-1,86	neutral	-2,06	low_impact	1,62	neutral	0,79	neutral	0,44	deleterious	0,68	8,69	0,54	0,6	NA	NA	disease	0,51	disease	0,6	disease	0,68	4	neutral	0,76	neutral	0,42	neutral	-6	neutral	0,42	medium_impact	-0,48	medium_impact	-0,14	medium_impact	0,48	0,31	0,8	32,68	25,6	N	0,32	N	0,7	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10886	10886	A	T	MI.16585	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	127	43	N	Y	Aac/Tac	-7,55	0	0	benign	0,03	neutral	1	neutral	1,49	neutral	-1,23	neutral	-1,81	medium_impact	2,17	neutral	0,75	neutral	0,94	neutral	1,38	12,7	0,13	0,4	NA	NA	disease	0,64	neutral	0,34	neutral	0,49	0	neutral	0,03	deleterious	0,99	neutral	-3	deleterious	0,71	medium_impact	0,7	high_impact	1,88	medium_impact	1,02	0,24	0,8	32,68	25,6	N	0,28	N	0,21	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10886	10886	A	C	MI.16586	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	127	43	N	H	Aac/Cac	-7,55	0	0	benign	0,02	neutral	0,52	neutral	1,46	neutral	-1,96	neutral	-1,24	low_impact	1	neutral	0,76	neutral	0,92	neutral	1,19	11,68	0,4	0,5	NA	NA	disease	0,56	neutral	0,36	neutral	0,47	1	neutral	0,46	deleterious	0,75	neutral	-6	deleterious	0,69	medium_impact	0,87	medium_impact	0,22	medium_impact	-0,14	0,17	0,8	32,68	25,6	N	0,31	N	0,31	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10887	10887	A	T	MI.16587	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	128	43	N	I	aAc/aTc	-0,4	0	0	possibly_damaging	0,75	neutral	0,43	neutral	1,47	neutral	-1,76	deleterious	-3,47	low_impact	1,72	neutral	0,79	neutral	0,68	deleterious	2,13	17,03	0,13	0,4	NA	NA	disease	0,73	neutral	0,32	disease	0,54	1	neutral	0,75	neutral	0,34	neutral	-3	deleterious	0,66	low_impact	-1,17	medium_impact	0,13	medium_impact	0,58	0,16	0,8	32,68	25,6	N	0,28	N	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10887	10887	A	G	MI.16588	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	128	43	N	S	aAc/aGc	-0,4	0	0	benign	0,03	neutral	0,44	neutral	1,57	neutral	-0,11	neutral	-1,52	low_impact	1,05	neutral	0,73	neutral	0,95	neutral	-0,38	0,43	0,55	0,6	NA	NA	neutral	0,42	disease	0,56	neutral	0,36	3	neutral	0,53	deleterious	0,71	neutral	-6	neutral	0,17	medium_impact	0,7	medium_impact	0,14	medium_impact	-0,09	0,15	0,8	32,68	25,6	N	0,38	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10887	10887	A	C	MI.16589	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	128	43	N	T	aAc/aCc	-0,4	0	0	benign	0,36	neutral	0,4	neutral	1,51	neutral	-0,92	neutral	-1,89	low_impact	1,72	neutral	0,75	neutral	0,74	deleterious	0,07	3,32	0,38	0,5	NA	NA	neutral	0,46	neutral	0,46	neutral	0,24	5	neutral	0,53	deleterious	0,52	neutral	-6	neutral	0,34	medium_impact	-0,48	medium_impact	0,1	medium_impact	0,58	0,23	0,8	32,68	25,6	N	0,39	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8466	8466	A	C	MI.1659	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	101	34	H	P	cAc/cCc	-0,57	0	0	probably_damaging	0,98	neutral	0,39	neutral	0,71	deleterious	-7,32	neutral	-1,59	neutral_impact	0,24	neutral	0,99	neutral	0,97	deleterious	2,02	16,31	0,49682067	0,85	neutral	0,09	neutral	0,22	neutral	0,43	neutral	0,09	8	deleterious	0,98	neutral	0,21	neutral	-2	deleterious	0,68	low_impact	-2,36	medium_impact	0,18	medium_impact	-0,89	0,41	0,85	10,29	8,62	N	0,44	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10888	10888	C	G	MI.16590	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	129	43	N	K	aaC/aaG	0,06	0	0	benign	0,36	neutral	0,37	neutral	1,56	neutral	-0,26	neutral	-1,51	low_impact	1,48	neutral	0,73	neutral	0,7	neutral	-0,33	0,56	0,46	0,55	NA	NA	neutral	0,37	disease	0,62	neutral	0,36	3	neutral	0,56	deleterious	0,51	neutral	-6	neutral	0,4	medium_impact	-0,48	medium_impact	0,07	medium_impact	0,34	0,47	0,8	32,68	25,6	N	0,37	N	0,77	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10888	10888	C	A	MI.16591	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	129	43	N	K	aaC/aaA	0,06	0	0	benign	0,36	neutral	0,37	neutral	1,56	neutral	-0,26	neutral	-1,51	low_impact	1,48	neutral	0,73	neutral	0,7	deleterious	0,11	3,71	0,46	0,55	NA	NA	neutral	0,37	disease	0,62	neutral	0,36	3	neutral	0,56	deleterious	0,51	neutral	-6	neutral	0,4	medium_impact	-0,48	medium_impact	0,07	medium_impact	0,34	0,47	0,8	32,68	25,6	N	0,36	N	0,77	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10889	10889	C	G	MI.16592	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	130	44	Q	E	Caa/Gaa	-5,01	0	0	possibly_damaging	0,88	neutral	0,27	neutral	1,55	neutral	0,2	neutral	-1,22	medium_impact	2,8	neutral	0,79	neutral	0,53	neutral	1,39	12,71	0,33	0,5	NA	NA	neutral	0,33	neutral	0,47	neutral	0,16	7	neutral	0,9	neutral	0,2	NA	0	deleterious	0,71	low_impact	-1,53	medium_impact	-0,04	medium_impact	1,64	0,32	0,8	28,76	21,01	N	0,39	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10889	10889	C	A	MI.16593	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	130	44	Q	K	Caa/Aaa	-5,01	0	0	possibly_damaging	0,89	neutral	0,29	neutral	1,57	neutral	0,16	neutral	-1,4	medium_impact	2,8	neutral	0,79	neutral	0,56	deleterious	2,29	18,12	0,21	0,45	NA	NA	neutral	0,42	neutral	0,49	neutral	0,16	7	neutral	0,91	neutral	0,2	NA	0	deleterious	0,72	low_impact	-1,57	medium_impact	-0,02	medium_impact	1,64	0,44	0,8	28,76	21,01	N	0,43	N	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10890	10890	A	T	MI.16594	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	131	44	Q	L	cAa/cTa	-0,17	0	0	possibly_damaging	0,61	neutral	0,66	neutral	1,63	neutral	-1,04	deleterious	-2,57	low_impact	1,75	neutral	0,72	neutral	0,66	neutral	1,48	13,21	0,11	0,4	NA	NA	neutral	0,33	neutral	0,41	neutral	0,14	7	neutral	0,54	deleterious	0,53	neutral	-3	deleterious	0,72	medium_impact	-0,9	medium_impact	0,36	medium_impact	0,61	0,12	0,8	28,76	21,01	N	0,32	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10890	10890	A	C	MI.16595	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	131	44	Q	P	cAa/cCa	-0,17	0	0	probably_damaging	0,98	neutral	0,22	neutral	1,54	neutral	-1,57	deleterious	-2,57	low_impact	1,51	neutral	0,74	neutral	0,64	neutral	1,72	14,51	0,06	0,35	NA	NA	neutral	0,41	disease	0,55	neutral	0,33	3	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,77	low_impact	-2,31	medium_impact	-0,11	medium_impact	0,37	0,32	0,8	28,76	21,01	N	0,38	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10890	10890	A	G	MI.16596	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	131	44	Q	R	cAa/cGa	-0,17	0	0	probably_damaging	0,94	neutral	0,35	neutral	1,54	neutral	-0,54	neutral	-1,51	medium_impact	2,44	neutral	0,83	neutral	0,64	neutral	1,73	14,57	0,23	0,45	NA	NA	neutral	0,39	disease	0,53	neutral	0,34	3	neutral	0,94	neutral	0,21	deleterious	1	deleterious	0,75	low_impact	-1,84	medium_impact	0,05	medium_impact	1,29	0,11	0,8	28,76	21,01	N	0,37	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10891	10891	A	C	MI.16597	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	132	44	Q	H	caA/caC	1,68	0	0	probably_damaging	0,99	neutral	0,54	neutral	1,54	neutral	-1,37	neutral	-1,53	medium_impact	2,1	neutral	0,75	neutral	0,88	neutral	1	10,68	0,29	0,45	NA	NA	neutral	0,23	neutral	0,27	neutral	0,16	7	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,73	low_impact	-2,59	medium_impact	0,24	medium_impact	0,95	0,56	0,8	28,76	21,01	N	0,39	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10891	10891	A	T	MI.16598	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	132	44	Q	H	caA/caT	1,68	0	0	probably_damaging	0,99	neutral	0,54	neutral	1,54	neutral	-1,37	neutral	-1,53	medium_impact	2,1	neutral	0,75	neutral	0,88	neutral	1,17	11,6	0,29	0,45	NA	NA	neutral	0,23	neutral	0,27	neutral	0,16	7	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,73	low_impact	-2,59	medium_impact	0,24	medium_impact	0,95	0,56	0,8	28,76	21,01	N	0,39	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10892	10892	A	T	MI.16599	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	133	45	I	F	Atc/Ttc	-2,48	0	0,01	possibly_damaging	0,49	neutral	0,72	neutral	1,57	neutral	-1,41	neutral	-0,11	neutral_impact	-1,01	neutral	0,78	neutral	0,97	neutral	-0,58	0,14	0,16	0,45	NA	NA	neutral	0,21	neutral	0,2	neutral	0,18	6	neutral	0,39	deleterious	0,62	neutral	-3	neutral	0,27	medium_impact	-0,7	medium_impact	0,43	low_impact	-2,13	0,61	0,8	35,08	27,64	N	0,31	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8603	8603	T	A	MI.166	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	77	26	F	Y	tTt/tAt	-0,33	0	0	benign	0,21	neutral	0,07	neutral	4,3	neutral	-1,05	neutral	-1,92	medium_impact	2,04	neutral	0,85	neutral	0,62	deleterious	2,39	18,78	0,35	0,65	disease	0,78	neutral	0,42	neutral	0,39	disease	0,66	3	neutral	0,92	neutral	0,43	neutral	-3	neutral	0,36	medium_impact	-0,21	medium_impact	-0,34	medium_impact	0,65	0,49	0,9	15,49	8,03	N	0,44	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8466	8466	A	G	MI.1660	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	101	34	H	R	cAc/cGc	-0,57	0	0	probably_damaging	0,97	neutral	0,38	neutral	0,72	deleterious	-6,46	deleterious	-3,64	medium_impact	2,5	neutral	0,99	neutral	0,5	deleterious	2,15	17,16	0,73708172	0,85	neutral	0,31	neutral	0,2	neutral	0,46	neutral	0,13	7	neutral	0,97	neutral	0,21	deleterious	1	deleterious	0,69	low_impact	-2,19	medium_impact	0,17	medium_impact	1,05	0,29	0,85	10,29	8,62	N	0,52	P	0,48	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10892	10892	A	C	MI.16600	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	133	45	I	L	Atc/Ctc	-2,48	0	0,01	benign	0,05	neutral	0,67	neutral	1,61	neutral	-0,23	neutral	0,18	neutral_impact	-0,12	neutral	0,72	neutral	0,97	neutral	-0,69	0,08	0,26	0,45	NA	NA	neutral	0,08	neutral	0,28	neutral	0,22	6	neutral	0,26	deleterious	0,81	neutral	-6	neutral	0,08	medium_impact	0,48	medium_impact	0,37	low_impact	-1,25	0,48	0,8	35,08	27,64	N	0,39	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10892	10892	A	G	MI.16601	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	133	45	I	V	Atc/Gtc	-2,48	0	0,01	benign	0,05	neutral	0,51	neutral	1,6	neutral	-0,14	neutral	0,13	neutral_impact	0,34	neutral	0,81	neutral	0,8	neutral	-1,05	0,01	0,55	0,6	NA	NA	neutral	0,06	neutral	0,35	neutral	0,19	6	neutral	0,44	deleterious	0,73	neutral	-6	neutral	0,07	medium_impact	0,48	medium_impact	0,21	medium_impact	-0,79	0,42	0,8	35,08	27,64	N	0,37	N	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10893	10893	T	C	MI.16602	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	134	45	I	T	aTc/aCc	-2,94	0	0	benign	0	neutral	0,41	neutral	1,61	neutral	-1,19	neutral	1,08	neutral_impact	-1,07	neutral	0,73	neutral	0,96	neutral	-0,6	0,13	0,23	0,45	NA	NA	neutral	0,08	neutral	0,26	neutral	0,22	6	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,08	high_impact	2,1	medium_impact	0,11	low_impact	-2,18	0,31	0,8	35,08	27,64	N	0,4	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10893	10893	T	G	MI.16603	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	134	45	I	S	aTc/aGc	-2,94	0	0	benign	0,01	neutral	0,43	neutral	1,69	neutral	-1,12	neutral	0,9	neutral_impact	-1,18	neutral	0,73	neutral	0,97	deleterious	0,39	6,51	0,1	0,4	NA	NA	neutral	0,16	neutral	0,27	neutral	0,22	6	neutral	0,56	deleterious	0,71	neutral	-6	neutral	0,12	medium_impact	1,16	medium_impact	0,13	low_impact	-2,29	0,22	0,8	35,08	27,64	N	0,4	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10893	10893	T	A	MI.16604	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	134	45	I	N	aTc/aAc	-2,94	0	0	benign	0,11	neutral	0,32	neutral	1,67	neutral	-2,47	neutral	0,57	neutral_impact	-1,32	neutral	0,72	neutral	0,97	deleterious	0,87	9,88	0,2	0,45	NA	NA	neutral	0,29	neutral	0,26	neutral	0,16	7	neutral	0,63	deleterious	0,61	neutral	-6	neutral	0,21	medium_impact	0,14	medium_impact	0,02	low_impact	-2,43	0,15	0,8	35,08	27,64	N	0,42	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10894	10894	C	G	MI.16605	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	135	45	I	M	atC/atG	-1,32	0	0	possibly_damaging	0,68	neutral	0,24	neutral	1,58	neutral	-1,8	neutral	0,45	neutral_impact	-0,46	neutral	0,73	neutral	0,95	deleterious	0,11	3,74	0,41	0,5	NA	NA	neutral	0,06	neutral	0,2	neutral	0,21	6	neutral	0,8	neutral	0,28	neutral	-3	neutral	0,39	low_impact	-1,03	medium_impact	-0,08	low_impact	-1,58	0,61	0,8	35,08	27,64	N	0,52	P	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10894	10894	C	A	MI.16606	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	135	45	I	M	atC/atA	-1,32	0	0	possibly_damaging	0,68	neutral	0,24	neutral	1,58	neutral	-1,8	neutral	0,45	neutral_impact	-0,46	neutral	0,73	neutral	0,95	deleterious	0,57	7,95	0,41	0,5	NA	NA	neutral	0,06	neutral	0,2	neutral	0,21	6	neutral	0,8	neutral	0,28	neutral	-3	neutral	0,39	low_impact	-1,03	medium_impact	-0,08	low_impact	-1,58	0,61	0,8	35,08	27,64	N	0,52	P	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10895	10895	A	T	MI.16607	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	136	46	N	Y	Aac/Tac	-20	0	0	probably_damaging	0,96	neutral	1	neutral	1,54	neutral	-2,22	neutral	-1,59	medium_impact	2,03	neutral	0,78	neutral	0,71	deleterious	2,21	17,57	0,15	0,4	NA	NA	neutral	0,33	neutral	0,29	neutral	0,16	7	neutral	0,96	deleterious	0,52	deleterious	1	deleterious	0,66	low_impact	-2,01	high_impact	1,88	medium_impact	0,88	0,22	0,8	19,61	16,67	N	0,24	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10895	10895	A	G	MI.16608	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	136	46	N	D	Aac/Gac	-20	0	0	benign	0,05	neutral	0,29	neutral	1,57	neutral	-0,64	neutral	-0,15	low_impact	1,48	neutral	0,78	neutral	0,95	deleterious	0,27	5,45	0,51	0,6	NA	NA	neutral	0,21	neutral	0,49	neutral	0,18	6	neutral	0,69	deleterious	0,62	neutral	-6	neutral	0,11	medium_impact	0,48	medium_impact	-0,02	medium_impact	0,34	0,28	0,8	19,61	16,67	N	0,44	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10895	10895	A	C	MI.16609	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	136	46	N	H	Aac/Cac	-20	0	0	probably_damaging	0,96	neutral	0,51	neutral	1,55	neutral	-1,55	neutral	-0,97	medium_impact	2,38	neutral	0,83	neutral	0,84	neutral	1,66	14,2	0,34	0,5	NA	NA	neutral	0,33	neutral	0,34	neutral	0,15	7	neutral	0,96	neutral	0,28	deleterious	1	deleterious	0,65	low_impact	-2,01	medium_impact	0,21	medium_impact	1,23	0,2	0,8	19,61	16,67	N	0,36	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8467	8467	C	G	MI.1661	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	102	34	H	Q	caC/caG	-4,04	0	0	probably_damaging	0,98	neutral	0,31	neutral	0,71	deleterious	-7,1	deleterious	-3,07	low_impact	1,81	neutral	1	neutral	0,63	deleterious	2,31	18,21	0,7892424	0,85	neutral	0,32	neutral	0,21	neutral	0,47	neutral	0,13	7	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,67	low_impact	-2,36	medium_impact	0,1	medium_impact	0,45	0,51	0,85	10,29	8,62	N	0,51	P	0,18	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10896	10896	A	G	MI.16610	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	137	46	N	S	aAc/aGc	-4,78	0	0	benign	0,09	neutral	0,65	neutral	1,63	neutral	0,19	neutral	0,54	low_impact	1,18	neutral	0,76	neutral	0,99	neutral	-1,54	0	0,45	0,55	NA	NA	neutral	0,07	neutral	0,28	neutral	0,21	6	neutral	0,26	deleterious	0,78	neutral	-6	neutral	0,26	medium_impact	0,23	medium_impact	0,35	medium_impact	0,04	0,27	0,8	19,61	16,67	N	0,4	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10896	10896	A	C	MI.16611	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	137	46	N	T	aAc/aCc	-4,78	0	0	possibly_damaging	0,64	neutral	0,45	neutral	1,6	neutral	-0,33	neutral	-0,4	medium_impact	2,17	neutral	0,74	neutral	0,98	neutral	1,43	12,92	0,32	0,5	NA	NA	neutral	0,22	neutral	0,27	neutral	0,15	7	neutral	0,64	neutral	0,41	NA	0	neutral	0,4	medium_impact	-0,95	medium_impact	0,15	medium_impact	1,02	0,24	0,8	19,61	16,67	N	0,47	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10896	10896	A	T	MI.16612	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	137	46	N	I	aAc/aTc	-4,78	0	0	probably_damaging	0,93	neutral	0,39	neutral	1,55	neutral	-1,59	neutral	-1,79	medium_impact	2,17	neutral	0,83	neutral	0,81	deleterious	2,62	20,3	0,17	0,45	NA	NA	neutral	0,46	neutral	0,41	neutral	0,25	5	neutral	0,93	neutral	0,23	deleterious	1	deleterious	0,63	low_impact	-1,77	medium_impact	0,09	medium_impact	1,02	0,15	0,8	19,61	16,67	N	0,35	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10897	10897	C	A	MI.16613	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	138	46	N	K	aaC/aaA	-2,24	0	0	possibly_damaging	0,64	neutral	0,33	neutral	1,58	neutral	0,11	neutral	-0,94	medium_impact	2,38	neutral	0,79	neutral	0,56	deleterious	2,49	19,42	0,35	0,5	NA	NA	neutral	0,44	neutral	0,49	neutral	0,21	6	neutral	0,72	neutral	0,35	NA	0	neutral	0,4	medium_impact	-0,95	medium_impact	0,03	medium_impact	1,23	0,33	0,8	19,61	16,67	N	0,38	N	0,66	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10897	10897	C	G	MI.16614	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	138	46	N	K	aaC/aaG	-2,24	0	0	possibly_damaging	0,64	neutral	0,33	neutral	1,58	neutral	0,11	neutral	-0,94	medium_impact	2,38	neutral	0,79	neutral	0,56	deleterious	2,01	16,29	0,35	0,5	NA	NA	neutral	0,44	neutral	0,49	neutral	0,21	6	neutral	0,72	neutral	0,35	NA	0	neutral	0,4	medium_impact	-0,95	medium_impact	0,03	medium_impact	1,23	0,33	0,8	19,61	16,67	N	0,37	N	0,66	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10898	10898	A	G	MI.16615	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	139	47	N	D	Aac/Gac	-5,93	0	0	benign	0,25	neutral	0,21	neutral	1,58	neutral	-0,57	neutral	0,74	low_impact	1,14	neutral	0,76	neutral	0,98	neutral	-0,42	0,34	0,45	0,55	NA	NA	neutral	0,12	neutral	0,33	neutral	0,22	6	neutral	0,75	deleterious	0,48	neutral	-6	neutral	0,26	medium_impact	-0,27	medium_impact	-0,12	medium_impact	0	0,35	0,8	32,03	28,79	N	0,46	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10898	10898	A	C	MI.16616	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	139	47	N	H	Aac/Cac	-5,93	0	0	possibly_damaging	0,8	neutral	0,53	neutral	1,49	neutral	-1,7	neutral	-0,84	medium_impact	2,17	neutral	0,81	neutral	0,84	deleterious	2,57	19,89	0,32	0,5	NA	NA	neutral	0,28	disease	0,52	neutral	0,31	4	neutral	0,78	neutral	0,37	NA	0	deleterious	0,61	low_impact	-1,28	medium_impact	0,23	medium_impact	1,02	0,29	0,8	32,03	28,79	N	0,29	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10898	10898	A	T	MI.16617	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	139	47	N	Y	Aac/Tac	-5,93	0	0	possibly_damaging	0,85	neutral	1	neutral	1,49	neutral	-1,85	neutral	-1,2	low_impact	1,49	neutral	0,78	neutral	0,81	deleterious	3,11	22,5	0,12	0,4	NA	NA	neutral	0,3	neutral	0,32	neutral	0,14	7	neutral	0,85	deleterious	0,58	neutral	-3	deleterious	0,62	low_impact	-1,43	high_impact	1,88	medium_impact	0,35	0,35	0,8	32,03	28,79	N	0,22	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10899	10899	A	G	MI.16618	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	140	47	N	S	aAc/aGc	0,06	0	0	benign	0,03	neutral	0,41	neutral	1,59	neutral	0,33	neutral	-0,45	low_impact	1,21	neutral	0,73	neutral	0,86	neutral	-0,18	1,18	0,51	0,6	NA	NA	neutral	0,16	neutral	0,32	neutral	0,21	6	neutral	0,57	deleterious	0,69	neutral	-6	neutral	0,11	medium_impact	0,7	medium_impact	0,11	medium_impact	0,07	0,23	0,8	32,03	28,79	N	0,44	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10899	10899	A	T	MI.16619	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	140	47	N	I	aAc/aTc	0,06	0	0	benign	0,04	neutral	0,39	neutral	1,52	neutral	-0,96	neutral	-1,36	low_impact	1,83	neutral	0,81	neutral	0,89	deleterious	2,41	18,91	0,15	0,4	NA	NA	neutral	0,41	neutral	0,34	neutral	0,16	7	neutral	0,58	deleterious	0,68	neutral	-6	deleterious	0,56	medium_impact	0,58	medium_impact	0,09	medium_impact	0,68	0,19	0,8	32,03	28,79	N	0,37	N	0,5	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8467	8467	C	A	MI.1662	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	102	34	H	Q	caC/caA	-4,04	0	0	probably_damaging	0,98	neutral	0,31	neutral	0,71	deleterious	-7,1	deleterious	-3,07	low_impact	1,81	neutral	1	neutral	0,63	deleterious	2,64	20,4	0,7892424	0,85	neutral	0,32	neutral	0,21	neutral	0,47	neutral	0,13	7	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,67	low_impact	-2,36	medium_impact	0,1	medium_impact	0,45	0,51	0,85	10,29	8,62	N	0,51	P	0,18	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10899	10899	A	C	MI.16620	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	140	47	N	T	aAc/aCc	0,06	0	0	benign	0,03	neutral	0,39	neutral	1,55	neutral	-0,21	neutral	-0,52	neutral_impact	-0,15	neutral	0,72	neutral	0,96	deleterious	-0,05	2,13	0,28	0,45	NA	NA	neutral	0,17	neutral	0,3	neutral	0,2	6	neutral	0,59	deleterious	0,68	neutral	-6	neutral	0,21	medium_impact	0,7	medium_impact	0,09	low_impact	-1,27	0,48	0,8	32,03	28,79	N	0,4	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10900	10900	C	A	MI.16621	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	141	47	N	K	aaC/aaA	1,21	0	0	benign	0,25	neutral	0,28	neutral	1,55	neutral	0,15	neutral	-0,83	low_impact	1,83	neutral	0,78	neutral	0,69	neutral	1,34	12,48	0,4	0,5	NA	NA	neutral	0,39	disease	0,57	neutral	0,36	3	neutral	0,66	deleterious	0,52	neutral	-6	neutral	0,32	medium_impact	-0,27	medium_impact	-0,03	medium_impact	0,68	0,44	0,8	32,03	28,79	N	0,37	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10900	10900	C	G	MI.16622	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	141	47	N	K	aaC/aaG	1,21	0	0	benign	0,25	neutral	0,28	neutral	1,55	neutral	0,15	neutral	-0,83	low_impact	1,83	neutral	0,78	neutral	0,69	deleterious	0,86	9,82	0,4	0,5	NA	NA	neutral	0,39	disease	0,57	neutral	0,36	3	neutral	0,66	deleterious	0,52	neutral	-6	neutral	0,32	medium_impact	-0,27	medium_impact	-0,03	medium_impact	0,68	0,44	0,8	32,03	28,79	N	0,37	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10901	10901	A	G	MI.16623	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	142	48	N	D	Aac/Gac	-5,24	0	0	possibly_damaging	0,52	neutral	0,2	neutral	1,56	neutral	-0,54	neutral	-1,28	medium_impact	2,13	neutral	0,83	neutral	0,55	deleterious	0,57	7,94	0,73	0,75	NA	NA	neutral	0,26	neutral	0,45	neutral	0,17	7	neutral	0,79	neutral	0,34	NA	0	neutral	0,35	medium_impact	-0,75	medium_impact	-0,14	medium_impact	0,98	0,33	0,8	29,85	20,94	N	0,42	N	0,69	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10901	10901	A	C	MI.16624	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	142	48	N	H	Aac/Cac	-5,24	0	0	probably_damaging	0,92	neutral	0,53	neutral	1,54	neutral	-1,34	neutral	-1,36	medium_impact	2,13	neutral	0,8	neutral	0,91	neutral	1,13	11,36	0,47	0,55	NA	NA	neutral	0,31	neutral	0,29	neutral	0,17	7	neutral	0,91	neutral	0,31	deleterious	1	deleterious	0,63	low_impact	-1,71	medium_impact	0,23	medium_impact	0,98	0,15	0,8	29,85	20,94	N	0,3	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10901	10901	A	T	MI.16625	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	142	48	N	Y	Aac/Tac	-5,24	0	0	probably_damaging	0,94	neutral	1	neutral	1,58	neutral	-2,19	neutral	-1,56	low_impact	1,79	neutral	0,78	neutral	0,66	neutral	1,4	12,77	0,13	0,4	NA	NA	neutral	0,39	neutral	0,24	neutral	0,17	7	neutral	0,94	deleterious	0,53	neutral	-2	deleterious	0,67	low_impact	-1,84	high_impact	1,88	medium_impact	0,65	0,16	0,8	29,85	20,94	N	0,22	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10902	10902	A	C	MI.16626	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	143	48	N	T	aAc/aCc	-0,4	0	0	possibly_damaging	0,52	neutral	0,43	neutral	1,58	neutral	-0,21	neutral	0,24	low_impact	1,88	neutral	0,69	neutral	0,98	neutral	-0,85	0,03	0,39	0,5	NA	NA	neutral	0,11	neutral	0,19	neutral	0,24	5	neutral	0,57	neutral	0,46	neutral	-3	neutral	0,27	medium_impact	-0,75	medium_impact	0,13	medium_impact	0,73	0,25	0,8	29,85	20,94	P	0,59	P	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10902	10902	A	T	MI.16627	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	143	48	N	I	aAc/aTc	-0,4	0	0	possibly_damaging	0,89	neutral	0,4	neutral	1,54	neutral	-2,03	neutral	-1,59	medium_impact	2	neutral	0,77	neutral	0,83	deleterious	2,51	19,52	0,15	0,4	NA	NA	neutral	0,45	neutral	0,4	neutral	0,19	6	neutral	0,89	neutral	0,26	NA	0	deleterious	0,6	low_impact	-1,57	medium_impact	0,1	medium_impact	0,85	0,11	0,8	29,85	20,94	N	0,38	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10902	10902	A	G	MI.16628	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	143	48	N	S	aAc/aGc	-0,4	0	0	benign	0,05	neutral	0,43	neutral	1,65	neutral	0,08	neutral	-0,41	low_impact	1,19	neutral	0,76	neutral	0,97	deleterious	0,08	3,36	0,61	0,65	NA	NA	neutral	0,21	neutral	0,24	neutral	0,18	6	neutral	0,53	deleterious	0,69	neutral	-6	neutral	0,12	medium_impact	0,48	medium_impact	0,13	medium_impact	0,05	0,2	0,8	29,85	20,94	N	0,45	N	0,55	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10903	10903	C	A	MI.16629	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	144	48	N	K	aaC/aaA	-1,78	0	0	possibly_damaging	0,52	neutral	0,28	neutral	1,61	neutral	0,18	neutral	-1,32	medium_impact	2,68	neutral	0,8	neutral	0,54	neutral	1,3	12,25	0,56	0,6	NA	NA	neutral	0,43	neutral	0,46	neutral	0,18	6	neutral	0,7	neutral	0,38	NA	0	neutral	0,4	medium_impact	-0,75	medium_impact	-0,03	medium_impact	1,53	0,42	0,8	29,85	20,94	N	0,39	N	0,83	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8468	8468	C	A	MI.1663	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	103	35	L	M	Cta/Ata	-3,8	0	0	probably_damaging	1	neutral	0,27	neutral	1,54	neutral	-1,13	neutral	-0,12	low_impact	1,14	neutral	1	neutral	0,75	deleterious	2,5	19,5	0,52090386	0,85	neutral	0,39	neutral	0,07	neutral	0,22	neutral	0,06	9	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,65	low_impact	-3,6	medium_impact	0,05	medium_impact	-0,12	0,61	0,85	19,12	9,43	P	0,57	P	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10903	10903	C	G	MI.16630	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	144	48	N	K	aaC/aaG	-1,78	0	0	possibly_damaging	0,52	neutral	0,28	neutral	1,61	neutral	0,18	neutral	-1,32	medium_impact	2,68	neutral	0,8	neutral	0,54	deleterious	0,82	9,59	0,56	0,6	NA	NA	neutral	0,43	neutral	0,46	neutral	0,18	6	neutral	0,7	neutral	0,38	NA	0	neutral	0,4	medium_impact	-0,75	medium_impact	-0,03	medium_impact	1,53	0,42	0,8	29,85	20,94	N	0,39	N	0,83	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10904	10904	C	A	MI.16631	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	145	49	L	M	Cta/Ata	-8,24	0	0	probably_damaging	0,98	neutral	0,23	neutral	1,48	neutral	-1,12	neutral	0,52	neutral_impact	0,7	neutral	0,76	neutral	0,84	deleterious	2,54	19,73	0,26	0,45	NA	NA	neutral	0,05	neutral	0,18	neutral	0,2	6	deleterious	0,99	neutral	0,13	neutral	-2	deleterious	0,66	low_impact	-2,31	medium_impact	-0,09	medium_impact	-0,43	0,39	0,8	32,9	33,04	P	0,56	P	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10904	10904	C	G	MI.16632	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	145	49	L	V	Cta/Gta	-8,24	0	0	possibly_damaging	0,86	neutral	0,5	neutral	1,51	neutral	-0,73	neutral	-0,09	low_impact	1,67	neutral	0,8	neutral	0,8	deleterious	1,96	15,95	0,3	0,45	NA	NA	neutral	0,12	neutral	0,3	neutral	0,23	6	neutral	0,84	neutral	0,32	neutral	-3	deleterious	0,67	low_impact	-1,46	medium_impact	0,2	medium_impact	0,53	0,31	0,8	32,9	33,04	N	0,35	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10905	10905	T	C	MI.16633	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	146	49	L	P	cTa/cCa	-0,86	0	0	probably_damaging	0,99	neutral	0,2	neutral	1,42	neutral	-2,5	neutral	0,32	low_impact	1,67	neutral	0,74	neutral	0,85	deleterious	2,45	19,14	0,09	0,35	NA	NA	disease	0,55	neutral	0,37	neutral	0,47	1	deleterious	0,99	neutral	0,11	neutral	-2	deleterious	0,78	low_impact	-2,59	medium_impact	-0,14	medium_impact	0,53	0,16	0,8	32,9	33,04	N	0,46	N	0,71	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10905	10905	T	A	MI.16634	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	146	49	L	Q	cTa/cAa	-0,86	0	0	probably_damaging	0,99	neutral	0,29	neutral	1,42	neutral	-2,63	neutral	0,7	low_impact	1,67	neutral	0,79	neutral	0,75	deleterious	2,79	21,3	0,12	0,4	NA	NA	neutral	0,34	neutral	0,35	neutral	0,15	7	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,72	low_impact	-2,59	medium_impact	-0,02	medium_impact	0,53	0,14	0,8	32,9	33,04	N	0,41	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10905	10905	T	G	MI.16635	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	146	49	L	R	cTa/cGa	-0,86	0	0	probably_damaging	0,98	neutral	0,34	neutral	1,42	neutral	-2,78	neutral	0,28	low_impact	1,67	neutral	0,7	neutral	0,52	deleterious	2,88	21,8	0,09	0,35	NA	NA	disease	0,51	neutral	0,49	disease	0,52	0	deleterious	0,99	neutral	0,18	neutral	-2	deleterious	0,76	low_impact	-2,31	medium_impact	0,04	medium_impact	0,53	0,14	0,8	32,9	33,04	N	0,44	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10907	10907	T	A	MI.16636	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	148	50	F	I	Ttt/Att	-8,01	0	0,01	benign	0	neutral	0,41	neutral	1,58	neutral	-1,04	neutral	-0,14	neutral_impact	-0,34	neutral	0,79	neutral	0,88	neutral	0,98	10,54	0,24	0,45	NA	NA	neutral	0,15	neutral	0,48	neutral	0,22	6	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,11	high_impact	2,1	medium_impact	0,11	low_impact	-1,46	0,5	0,8	33,33	26,24	N	0,36	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10907	10907	T	G	MI.16637	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	148	50	F	V	Ttt/Gtt	-8,01	0	0,01	benign	0,03	neutral	0,51	neutral	1,61	neutral	-0,98	neutral	-0,39	neutral_impact	0	neutral	0,82	neutral	0,77	deleterious	0,61	8,24	0,11	0,4	NA	NA	neutral	0,17	neutral	0,49	neutral	0,21	6	neutral	0,46	deleterious	0,74	neutral	-6	neutral	0,09	medium_impact	0,7	medium_impact	0,21	low_impact	-1,13	0,29	0,8	33,33	26,24	N	0,32	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10907	10907	T	C	MI.16638	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	148	50	F	L	Ttt/Ctt	-8,01	0	0,01	benign	0	neutral	0,7	neutral	1,64	neutral	-0,54	neutral	0,57	neutral_impact	-2,1	neutral	0,78	neutral	0,98	neutral	-0,45	0,3	0,27	0,45	NA	NA	neutral	0,09	neutral	0,26	neutral	0,2	6	neutral	0,29	deleterious	0,85	neutral	-6	neutral	0,07	high_impact	2,1	medium_impact	0,41	low_impact	-3,2	0,52	0,8	33,33	26,24	N	0,35	N	0,01	polymorphism	1	0	rs879094052	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10908	10908	T	C	MI.16639	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	149	50	F	S	tTt/tCt	-0,63	0	0	benign	0,01	neutral	0,47	neutral	1,71	neutral	-2,13	neutral	-0,79	neutral_impact	-1,79	neutral	0,71	neutral	0,92	neutral	0,93	10,25	0,05	0,35	NA	NA	neutral	0,19	disease	0,53	neutral	0,28	4	neutral	0,52	deleterious	0,73	neutral	-6	neutral	0,11	medium_impact	1,16	medium_impact	0,17	low_impact	-2,9	0,17	0,8	33,33	26,24	N	0,33	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8468	8468	C	G	MI.1664	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	103	35	L	V	Cta/Gta	-3,8	0	0	probably_damaging	0,97	neutral	0,6	neutral	1,56	neutral	-0,51	neutral	-0,75	low_impact	1,68	neutral	1	neutral	0,74	neutral	1,48	13,22	0,49944063	0,85	neutral	0,24	neutral	0,08	neutral	0,31	neutral	0,05	9	neutral	0,97	neutral	0,32	neutral	-2	deleterious	0,62	low_impact	-2,19	medium_impact	0,39	medium_impact	0,34	0,52	0,85	19,12	9,43	N	0,38	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10908	10908	T	G	MI.16640	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	149	50	F	C	tTt/tGt	-0,63	0	0	benign	0,01	neutral	0,19	neutral	1,57	deleterious	-3,72	neutral	-1,08	neutral_impact	0,34	neutral	0,77	neutral	0,63	neutral	1,14	11,45	0,07	0,35	NA	NA	neutral	0,41	neutral	0,36	neutral	0,15	7	neutral	0,81	deleterious	0,59	neutral	-6	deleterious	0,43	medium_impact	1,16	medium_impact	-0,15	medium_impact	-0,79	0,21	0,8	33,33	26,24	N	0,39	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10908	10908	T	A	MI.16641	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	149	50	F	Y	tTt/tAt	-0,63	0	0	benign	0,01	neutral	1	neutral	1,59	neutral	-2,01	neutral	0,33	neutral_impact	0	neutral	0,73	neutral	0,96	deleterious	0,51	7,53	0,2	0,45	NA	NA	neutral	0,11	neutral	0,28	neutral	0,21	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,16	high_impact	1,88	low_impact	-1,13	0,54	0,8	33,33	26,24	N	0,32	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10909	10909	T	A	MI.16642	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	150	50	F	L	ttT/ttA	-0,17	0	0	benign	0	neutral	0,7	neutral	1,64	neutral	-0,54	neutral	0,57	neutral_impact	-2,1	neutral	0,78	neutral	0,98	deleterious	0,06	3,18	0,27	0,45	NA	NA	neutral	0,09	neutral	0,26	neutral	0,2	6	neutral	0,29	deleterious	0,85	neutral	-6	neutral	0,07	high_impact	2,1	medium_impact	0,41	low_impact	-3,2	0,52	0,8	33,33	26,24	N	0,36	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10909	10909	T	G	MI.16643	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	150	50	F	L	ttT/ttG	-0,17	0	0	benign	0	neutral	0,7	neutral	1,64	neutral	-0,54	neutral	0,57	neutral_impact	-2,1	neutral	0,78	neutral	0,98	deleterious	0,02	2,77	0,27	0,45	NA	NA	neutral	0,09	neutral	0,26	neutral	0,2	6	neutral	0,29	deleterious	0,85	neutral	-6	neutral	0,07	high_impact	2,1	medium_impact	0,41	low_impact	-3,2	0,52	0,8	33,33	26,24	N	0,35	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10910	10910	A	T	MI.16644	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	151	51	S	C	Agc/Tgc	-2,94	0	0	possibly_damaging	0,84	neutral	0,17	neutral	1,49	deleterious	-4,49	neutral	-2,25	low_impact	0,98	neutral	0,8	neutral	0,46	neutral	1,76	14,73	0,14	0,4	NA	NA	neutral	0,45	neutral	0,49	neutral	0,26	5	neutral	0,92	neutral	0,17	neutral	-3	deleterious	0,57	low_impact	-1,39	medium_impact	-0,18	medium_impact	-0,16	0,17	0,8	18,95	19,87	N	0,35	N	0,72	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10910	10910	A	C	MI.16645	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	151	51	S	R	Agc/Cgc	-2,94	0	0	benign	0,34	neutral	0,34	neutral	1,5	neutral	-1,15	neutral	-1,24	low_impact	1,52	neutral	0,73	neutral	0,46	deleterious	0,71	8,92	0,13	0,4	NA	NA	neutral	0,45	disease	0,64	neutral	0,44	1	neutral	0,59	deleterious	0,5	neutral	-6	neutral	0,34	medium_impact	-0,45	medium_impact	0,04	medium_impact	0,38	0,31	0,8	18,95	19,87	N	0,34	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10910	10910	A	G	MI.16646	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	151	51	S	G	Agc/Ggc	-2,94	0	0	benign	0,01	neutral	0,34	neutral	1,51	neutral	-1,03	neutral	-0,97	low_impact	0,83	neutral	0,81	neutral	0,81	deleterious	0,35	6,15	0,3	0,45	NA	NA	neutral	0,17	neutral	0,44	neutral	0,24	5	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,21	medium_impact	1,16	medium_impact	0,04	medium_impact	-0,31	0,44	0,8	18,95	19,87	N	0,4	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10911	10911	G	C	MI.16647	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	152	51	S	T	aGc/aCc	1,44	0	0	benign	0,01	neutral	0,44	neutral	1,55	neutral	-0,88	neutral	-0,5	neutral_impact	0,2	neutral	0,82	neutral	0,95	neutral	-0,51	0,21	0,42	0,55	NA	NA	neutral	0,12	neutral	0,23	neutral	0,23	5	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,11	medium_impact	1,16	medium_impact	0,14	medium_impact	-0,93	0,42	0,8	18,95	19,87	N	0,41	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10911	10911	G	A	MI.16648	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	152	51	S	N	aGc/aAc	1,44	0	0	benign	0,01	neutral	0,44	neutral	1,59	neutral	-0,81	neutral	1,58	neutral_impact	-1,04	neutral	0,8	neutral	0,97	neutral	-1,21	0,01	0,7	0,75	NA	NA	neutral	0,09	neutral	0,26	neutral	0,22	6	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,19	medium_impact	1,16	medium_impact	0,14	low_impact	-2,16	0,47	0,8	18,95	19,87	N	0,36	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10911	10911	G	T	MI.16649	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	152	51	S	I	aGc/aTc	1,44	0	0	benign	0,01	neutral	0,42	neutral	1,5	neutral	-2,42	neutral	-2,11	low_impact	1,52	neutral	0,81	neutral	0,89	deleterious	0,83	9,65	0,13	0,4	NA	NA	neutral	0,43	neutral	0,48	neutral	0,2	6	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,15	medium_impact	1,16	medium_impact	0,12	medium_impact	0,38	0,26	0,8	18,95	19,87	N	0,37	N	0,88	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8469	8469	T	C	MI.1665	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	104	35	L	P	cTa/cCa	-4,27	0	0	probably_damaging	1	neutral	0,33	neutral	1,54	neutral	-1,12	neutral	-0,94	neutral_impact	-0,16	neutral	1	neutral	0,9	deleterious	2,51	19,51	0,46155204	0,85	neutral	0,48	neutral	0,15	neutral	0,26	neutral	0,07	9	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	0,12	low_impact	-1,24	0,56	0,85	19,12	9,43	N	0,51	P	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10913	10913	T	G	MI.16650	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	154	52	C	G	Tgt/Ggt	-3,17	0	0	benign	0,05	neutral	0,25	neutral	1,58	neutral	-0,03	neutral	-1,09	neutral_impact	0	neutral	0,81	neutral	0,62	deleterious	0,07	3,33	0,1	0,4	NA	NA	neutral	0,14	neutral	0,44	neutral	0,23	5	neutral	0,73	deleterious	0,6	neutral	-6	neutral	0,12	medium_impact	0,48	medium_impact	-0,07	low_impact	-1,13	0,23	0,8	23,09	23,28	N	0,38	N	0,61	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10913	10913	T	C	MI.16651	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	154	52	C	R	Tgt/Cgt	-3,17	0	0	benign	0,06	neutral	0,08	neutral	1,59	neutral	0,06	neutral	-0,74	neutral_impact	0	neutral	0,77	neutral	0,55	deleterious	0,24	5,08	0,06	0,35	NA	NA	neutral	0,26	disease	0,57	neutral	0,37	3	neutral	0,91	deleterious	0,51	neutral	-6	neutral	0,14	medium_impact	0,41	medium_impact	-0,39	low_impact	-1,13	0,06	0,8	23,09	23,28	N	0,37	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10913	10913	T	A	MI.16652	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	154	52	C	S	Tgt/Agt	-3,17	0	0	benign	0,04	neutral	0,26	neutral	1,7	neutral	2,51	neutral	0,19	neutral_impact	-1,84	neutral	0,76	neutral	0,96	neutral	-0,31	0,64	0,12	0,4	NA	NA	neutral	0,08	neutral	0,26	neutral	0,21	6	neutral	0,72	deleterious	0,61	neutral	-6	neutral	0,11	medium_impact	0,58	medium_impact	-0,05	low_impact	-2,95	0,39	0,8	23,09	23,28	N	0,45	N	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10914	10914	G	C	MI.16653	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	155	52	C	S	tGt/tCt	-1,09	0	0	benign	0,04	neutral	0,26	neutral	1,7	neutral	2,51	neutral	0,19	neutral_impact	-1,84	neutral	0,76	neutral	0,96	neutral	-0,63	0,11	0,12	0,4	NA	NA	neutral	0,08	neutral	0,26	neutral	0,21	6	neutral	0,72	deleterious	0,61	neutral	-6	neutral	0,11	medium_impact	0,58	medium_impact	-0,05	low_impact	-2,95	0,39	0,8	23,09	23,28	N	0,46	N	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10914	10914	G	A	MI.16654	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	155	52	C	Y	tGt/tAt	-1,09	0	0	benign	0	neutral	0,27	neutral	1,6	neutral	0,54	neutral	1,44	neutral_impact	-0,55	neutral	0,84	neutral	0,98	neutral	-0,7	0,07	0,1	0,4	NA	NA	neutral	0,16	neutral	0,23	neutral	0,22	6	neutral	0,73	deleterious	0,64	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	-0,04	low_impact	-1,67	0,22	0,8	23,09	23,28	N	0,39	N	0	polymorphism	1	0,01	rs878931758	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10914	10914	G	T	MI.16655	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	155	52	C	F	tGt/tTt	-1,09	0	0	benign	0	neutral	0,38	neutral	1,64	neutral	1,69	neutral	2,22	neutral_impact	-2,46	neutral	0,74	neutral	0,97	neutral	-0,92	0,02	0,11	0,4	NA	NA	neutral	0,15	neutral	0,19	neutral	0,22	6	neutral	0,62	deleterious	0,69	neutral	-6	neutral	0,09	high_impact	2,1	medium_impact	0,08	low_impact	-3,56	0,23	0,8	23,09	23,28	N	0,46	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10915	10915	T	G	MI.16656	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	156	52	C	W	tgT/tgG	-0,17	0	0,04	benign	0,32	deleterious	0,04	neutral	1,57	neutral	-1,29	neutral	0,37	neutral_impact	0	neutral	0,83	neutral	0,63	deleterious	2,1	16,83	0,08	0,35	NA	NA	neutral	0,22	neutral	0,47	neutral	0,16	7	neutral	0,95	neutral	0,36	neutral	-2	neutral	0,21	medium_impact	-0,41	medium_impact	-0,57	low_impact	-1,13	0,33	0,8	23,09	23,28	N	0,44	N	0,3	polymorphism	1	0,01	rs2857285	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10915	10915	T	A	MI.16657	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	156	52	C	W	tgT/tgA	-0,17	0	0,04	benign	0,32	deleterious	0,04	neutral	1,57	neutral	-1,29	neutral	0,37	neutral_impact	0	neutral	0,83	neutral	0,63	deleterious	2,25	17,81	0,08	0,35	NA	NA	neutral	0,22	neutral	0,47	neutral	0,16	7	neutral	0,95	neutral	0,36	neutral	-2	neutral	0,21	medium_impact	-0,41	medium_impact	-0,57	low_impact	-1,13	0,33	0,8	23,09	23,28	N	0,44	N	0,3	polymorphism	1	0,01	rs2857285	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10916	10916	T	C	MI.16658	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	157	53	S	P	Tcc/Ccc	-8,01	0	0	probably_damaging	1	neutral	0,06	neutral	1,32	deleterious	-3,52	deleterious	-3,13	medium_impact	2,98	neutral	0,71	damaging	0,15	deleterious	3,76	23,4	0,07	0,35	NA	NA	disease	0,69	neutral	0,45	disease	0,52	0	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,82	0,19	0,8	16,34	17,29	N	0,35	N	0,96	polymorphism	1	0,08	rs879188757	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10916	10916	T	A	MI.16659	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	157	53	S	T	Tcc/Acc	-8,01	0	0	probably_damaging	1	neutral	0,31	neutral	1,4	neutral	-1,56	neutral	-1,77	low_impact	1,66	neutral	0,76	damaging	0,24	deleterious	2,49	19,43	0,22	0,45	NA	NA	neutral	0,22	neutral	0,23	neutral	0,2	6	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	0,01	medium_impact	0,52	0,52	0,8	16,34	17,29	N	0,39	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8469	8469	T	G	MI.1666	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	104	35	L	R	cTa/cGa	-4,27	0	0	probably_damaging	1	neutral	0,52	neutral	1,56	neutral	-0,65	neutral	-1,64	low_impact	1,34	neutral	0,99	neutral	0,5	deleterious	2,57	19,92	0,36236553	0,85	neutral	0,31	neutral	0,36	neutral	0,44	neutral	0,16	7	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	0,31	medium_impact	0,05	0,45	0,85	19,12	9,43	N	0,39	N	0,29	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10916	10916	T	G	MI.16660	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	157	53	S	A	Tcc/Gcc	-8,01	0	0	probably_damaging	1	deleterious	0,04	neutral	1,38	neutral	-1,83	neutral	-2,01	medium_impact	2,63	neutral	0,73	damaging	0,19	deleterious	3,46	23	0,24	0,45	NA	NA	neutral	0,23	neutral	0,42	neutral	0,19	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,71	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,48	0,37	0,8	16,34	17,29	N	0,39	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10917	10917	C	G	MI.16661	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	158	53	S	C	tCc/tGc	0,29	0	0	probably_damaging	1	neutral	0,07	neutral	1,3	deleterious	-4,77	deleterious	-3,21	medium_impact	2,98	neutral	0,74	damaging	0,09	deleterious	3,43	23	0,08	0,35	NA	NA	disease	0,61	neutral	0,47	disease	0,51	0	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	-0,43	medium_impact	1,82	0,28	0,8	16,34	17,29	N	0,32	N	0,63	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10917	10917	C	A	MI.16662	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	158	53	S	Y	tCc/tAc	0,29	0	0	probably_damaging	1	neutral	0,15	neutral	1,31	deleterious	-3,82	deleterious	-3,51	medium_impact	2,98	neutral	0,75	damaging	0,09	deleterious	3,87	23,5	0,08	0,35	NA	NA	disease	0,58	neutral	0,45	disease	0,54	1	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,22	medium_impact	1,82	0,28	0,8	16,34	17,29	N	0,33	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10917	10917	C	T	MI.16663	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	158	53	S	F	tCc/tTc	0,29	0	0	probably_damaging	1	neutral	0,17	neutral	1,31	deleterious	-3,88	deleterious	-3,61	medium_impact	2,98	neutral	0,73	damaging	0,1	deleterious	4,1	23,7	0,09	0,35	NA	NA	disease	0,62	neutral	0,49	neutral	0,5	0	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,18	medium_impact	1,82	0,07	0,8	16,34	17,29	N	0,32	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10919	10919	C	T	MI.16664	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	160	54	P	S	Cca/Tca	-5,47	0	0	benign	0,02	neutral	0,42	neutral	1,65	neutral	1,21	neutral	0,64	low_impact	0,9	neutral	0,74	neutral	0,92	deleterious	-0,01	2,47	0,18	0,45	NA	NA	neutral	0,11	neutral	0,14	neutral	0,25	5	neutral	0,56	deleterious	0,7	neutral	-6	neutral	0,15	medium_impact	0,87	medium_impact	0,12	medium_impact	-0,24	0,12	0,8	33,33	23,33	N	0,54	P	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10919	10919	C	A	MI.16665	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	160	54	P	T	Cca/Aca	-5,47	0	0	benign	0	neutral	0,37	neutral	1,64	neutral	1	neutral	0,9	neutral_impact	0,02	neutral	0,81	neutral	0,98	neutral	-0,2	1,12	0,16	0,45	NA	NA	neutral	0,09	neutral	0,15	neutral	0,23	5	neutral	0,63	deleterious	0,69	neutral	-6	neutral	0,09	high_impact	2,1	medium_impact	0,07	low_impact	-1,11	0,53	0,8	33,33	23,33	N	0,49	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10919	10919	C	G	MI.16666	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	160	54	P	A	Cca/Gca	-5,47	0	0	benign	0	neutral	0,47	neutral	1,63	neutral	0,9	neutral	0,14	low_impact	1,15	neutral	0,8	neutral	0,81	neutral	-1,04	0,01	0,17	0,45	NA	NA	neutral	0,06	neutral	0,45	neutral	0,19	6	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,08	high_impact	2,1	medium_impact	0,17	medium_impact	0,01	0,53	0,8	33,33	23,33	N	0,41	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10920	10920	C	G	MI.16667	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	161	54	P	R	cCa/cGa	-7,32	0	0	benign	0,05	neutral	0,32	neutral	1,59	neutral	0,05	neutral	-0,04	low_impact	1,7	neutral	0,8	neutral	0,46	neutral	-0,07	1,99	0,1	0,4	NA	NA	neutral	0,23	disease	0,64	neutral	0,38	3	neutral	0,65	deleterious	0,64	neutral	-6	neutral	0,26	medium_impact	0,48	medium_impact	0,02	medium_impact	0,56	0,28	0,8	33,33	23,33	N	0,37	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10920	10920	C	A	MI.16668	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	161	54	P	Q	cCa/cAa	-7,32	0	0	benign	0,11	neutral	0,28	neutral	1,61	neutral	0,66	neutral	0,19	low_impact	1,24	neutral	0,76	neutral	0,77	deleterious	0,62	8,29	0,12	0,4	NA	NA	neutral	0,15	neutral	0,5	neutral	0,22	6	neutral	0,68	deleterious	0,59	neutral	-6	neutral	0,36	medium_impact	0,14	medium_impact	-0,03	medium_impact	0,1	0,36	0,8	33,33	23,33	N	0,44	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10920	10920	C	T	MI.16669	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	161	54	P	L	cCa/cTa	-7,32	0	0	benign	0	neutral	0,64	neutral	1,66	neutral	1,35	neutral	0,92	neutral_impact	-0,5	neutral	0,81	neutral	0,96	neutral	-0,07	1,96	0,13	0,4	NA	NA	neutral	0,11	neutral	0,38	neutral	0,24	5	neutral	0,36	deleterious	0,82	neutral	-6	neutral	0,08	high_impact	2,1	medium_impact	0,34	low_impact	-1,62	0,72	0,85	33,33	23,33	N	0,35	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8469	8469	T	A	MI.1667	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	104	35	L	Q	cTa/cAa	-4,27	0	0	probably_damaging	1	neutral	0,5	neutral	1,55	neutral	-0,96	neutral	-1,1	neutral_impact	0,61	neutral	1	neutral	0,89	deleterious	2,54	19,75	0,31439318	0,85	neutral	0,3	neutral	0,15	neutral	0,25	neutral	0,07	9	deleterious	0,99	neutral	0,25	neutral	-2	deleterious	0,66	low_impact	-3,6	medium_impact	0,29	medium_impact	-0,58	0,54	0,85	19,12	9,43	N	0,44	N	0,16	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10922	10922	A	C	MI.16670	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	163	55	T	P	Acc/Ccc	-6,4	0	0	benign	0,11	neutral	0,06	neutral	1,52	neutral	-2,3	neutral	-1,99	low_impact	1,32	neutral	0,74	neutral	0,37	deleterious	0,78	9,36	0,05	0,35	NA	NA	neutral	0,33	neutral	0,26	neutral	0,16	7	neutral	0,93	deleterious	0,48	neutral	-6	neutral	0,18	medium_impact	0,14	medium_impact	-0,47	medium_impact	0,18	0,32	0,8	25,05	18,84	N	0,42	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10922	10922	A	T	MI.16671	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	163	55	T	S	Acc/Tcc	-6,4	0	0	benign	0	neutral	0,24	neutral	1,59	neutral	0,05	neutral	-0,76	neutral_impact	0,34	neutral	0,78	neutral	0,97	neutral	-0,09	1,8	0,31	0,45	NA	NA	neutral	0,06	neutral	0,25	neutral	0,19	6	neutral	0,76	deleterious	0,62	neutral	-6	neutral	0,09	high_impact	2,1	medium_impact	-0,08	medium_impact	-0,79	0,55	0,8	25,05	18,84	N	0,48	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10922	10922	A	G	MI.16672	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	163	55	T	A	Acc/Gcc	-6,4	0	0	benign	0,01	neutral	0,25	neutral	1,61	neutral	0,32	neutral	-1,04	low_impact	1,32	neutral	0,79	neutral	0,86	deleterious	0,38	6,45	0,24	0,45	NA	NA	neutral	0,06	neutral	0,4	neutral	0,19	6	neutral	0,74	deleterious	0,62	neutral	-6	neutral	0,08	medium_impact	1,16	medium_impact	-0,07	medium_impact	0,18	0,4	0,8	25,05	18,84	N	0,49	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10923	10923	C	G	MI.16673	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	164	55	T	S	aCc/aGc	-2,71	0	0	benign	0	neutral	0,24	neutral	1,59	neutral	0,05	neutral	-0,76	neutral_impact	0,34	neutral	0,78	neutral	0,97	neutral	-0,48	0,25	0,31	0,45	NA	NA	neutral	0,06	neutral	0,25	neutral	0,19	6	neutral	0,76	deleterious	0,62	neutral	-6	neutral	0,09	high_impact	2,1	medium_impact	-0,08	medium_impact	-0,79	0,55	0,8	25,05	18,84	N	0,5	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10923	10923	C	A	MI.16674	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	164	55	T	N	aCc/aAc	-2,71	0	0	benign	0	neutral	0,19	neutral	1,56	neutral	-0,42	neutral	-1,28	neutral_impact	0,77	neutral	0,72	neutral	0,93	deleterious	0,31	5,76	0,26	0,45	NA	NA	neutral	0,14	neutral	0,28	neutral	0,25	5	neutral	0,81	deleterious	0,6	neutral	-6	neutral	0,11	high_impact	2,1	medium_impact	-0,15	medium_impact	-0,36	0,6	0,8	25,05	18,84	N	0,52	P	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10923	10923	C	T	MI.16675	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	164	55	T	I	aCc/aTc	-2,71	0	0	benign	0,02	neutral	0,43	neutral	1,61	neutral	0,4	neutral	-0,55	neutral_impact	0,42	neutral	0,79	neutral	0,96	deleterious	0,37	6,31	0,12	0,4	NA	NA	neutral	0,11	neutral	0,45	neutral	0,25	5	neutral	0,55	deleterious	0,71	neutral	-6	neutral	0,1	medium_impact	0,87	medium_impact	0,13	medium_impact	-0,71	0,66	0,8	25,05	18,84	N	0,36	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10925	10925	T	C	MI.16676	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	166	56	F	L	Ttt/Ctt	-2,71	0	0	benign	0,01	neutral	0,64	neutral	1,72	neutral	-0,79	neutral	-2,48	neutral_impact	0,64	neutral	0,75	neutral	0,82	deleterious	1,97	16,04	0,17	0,45	NA	NA	neutral	0,14	neutral	0,31	neutral	0,23	5	neutral	0,33	deleterious	0,82	neutral	-6	deleterious	0,68	medium_impact	1,16	medium_impact	0,34	medium_impact	-0,49	0,71	0,85	21,57	25,24	N	0,33	N	0,43	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10925	10925	T	A	MI.16677	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	166	56	F	I	Ttt/Att	-2,71	0	0	benign	0,25	deleterious	0,04	neutral	1,47	neutral	-1,76	deleterious	-2,86	medium_impact	2,58	neutral	0,77	neutral	0,56	deleterious	4,2	23,9	0,1	0,4	NA	NA	neutral	0,29	neutral	0,41	neutral	0,19	6	neutral	0,95	neutral	0,4	deleterious	1	deleterious	0,71	medium_impact	-0,27	medium_impact	-0,57	medium_impact	1,43	0,58	0,8	21,57	25,24	N	0,46	N	0,84	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10925	10925	T	G	MI.16678	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	166	56	F	V	Ttt/Gtt	-2,71	0	0	benign	0,36	neutral	0,07	neutral	1,48	neutral	-1,8	deleterious	-3,47	medium_impact	2,93	neutral	0,76	neutral	0,55	deleterious	3,87	23,5	0,06	0,35	NA	NA	neutral	0,36	disease	0,59	neutral	0,37	3	neutral	0,92	neutral	0,36	neutral	-3	deleterious	0,71	medium_impact	-0,48	medium_impact	-0,43	medium_impact	1,77	0,43	0,8	21,57	25,24	N	0,44	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10926	10926	T	C	MI.16679	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	167	56	F	S	tTt/tCt	1,21	0	0	possibly_damaging	0,81	deleterious	0,02	neutral	1,43	deleterious	-3,09	deleterious	-4,49	medium_impact	2,23	neutral	0,8	neutral	0,69	deleterious	2,87	21,7	0,02	0,35	NA	NA	neutral	0,45	disease	0,61	neutral	0,43	1	deleterious	0,99	neutral	0,11	deleterious	4	deleterious	0,74	low_impact	-1,31	medium_impact	-0,75	medium_impact	1,08	0,28	0,8	21,57	25,24	N	0,43	N	0,95	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8471	8471	C	T	MI.1668	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	106	36	P	S	Cct/Tct	-2,42	0	0	benign	0,02	neutral	0,72	neutral	2,03	neutral	0,4	neutral	-0,12	low_impact	0,98	neutral	1	neutral	0,96	neutral	-0,07	1,93	0,45913084	0,85	neutral	0,14	neutral	0,06	neutral	0,31	neutral	0,04	9	neutral	0,24	deleterious	0,85	neutral	-6	neutral	0,12	medium_impact	0,85	medium_impact	0,52	medium_impact	-0,26	0,23	0,85	19,12	8,87	N	0,43	N	0,35	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10926	10926	T	A	MI.16680	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	167	56	F	Y	tTt/tAt	1,21	0	0	benign	0,03	neutral	0,08	neutral	1,42	neutral	-2,75	neutral	-1,09	medium_impact	2,58	neutral	0,74	neutral	0,76	deleterious	2,2	17,52	0,12	0,4	NA	NA	neutral	0,15	neutral	0,28	neutral	0,17	7	neutral	0,92	deleterious	0,53	neutral	-3	deleterious	0,7	medium_impact	0,7	medium_impact	-0,39	medium_impact	1,43	0,56	0,8	21,57	25,24	P	0,56	P	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10926	10926	T	G	MI.16681	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	167	56	F	C	tTt/tGt	1,21	0	0	probably_damaging	0,95	deleterious	0,01	neutral	1,38	deleterious	-4,63	deleterious	-4,43	medium_impact	2,93	neutral	0,8	neutral	0,41	deleterious	3,89	23,5	0,03	0,35	NA	NA	disease	0,6	neutral	0,44	disease	0,5	0	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,74	low_impact	-1,92	medium_impact	-0,92	medium_impact	1,77	0,24	0,8	21,57	25,24	N	0,4	N	0,94	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10927	10927	T	G	MI.16682	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	168	56	F	L	ttT/ttG	-0,17	0	0,01	benign	0,01	neutral	0,64	neutral	1,72	neutral	-0,79	neutral	-2,48	neutral_impact	0,64	neutral	0,75	neutral	0,82	deleterious	2,27	17,94	0,17	0,45	NA	NA	neutral	0,14	neutral	0,31	neutral	0,23	5	neutral	0,33	deleterious	0,82	neutral	-6	deleterious	0,68	medium_impact	1,16	medium_impact	0,34	medium_impact	-0,49	0,71	0,85	21,57	25,24	N	0,34	N	0,43	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10927	10927	T	A	MI.16683	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	168	56	F	L	ttT/ttA	-0,17	0	0,01	benign	0,01	neutral	0,64	neutral	1,72	neutral	-0,79	neutral	-2,48	neutral_impact	0,64	neutral	0,75	neutral	0,82	deleterious	2,42	18,92	0,17	0,45	NA	NA	neutral	0,14	neutral	0,31	neutral	0,23	5	neutral	0,33	deleterious	0,82	neutral	-6	deleterious	0,68	medium_impact	1,16	medium_impact	0,34	medium_impact	-0,49	0,71	0,85	21,57	25,24	N	0,34	N	0,43	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10928	10928	T	G	MI.16684	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	169	57	S	A	Tcc/Gcc	-2,48	0	0	possibly_damaging	0,84	neutral	0,81	neutral	1,56	neutral	-0,2	neutral	-0,16	neutral_impact	0,44	neutral	0,73	neutral	0,61	neutral	1	10,67	0,21	0,45	NA	NA	neutral	0,03	disease	0,51	neutral	0,16	7	neutral	0,81	deleterious	0,49	neutral	-3	deleterious	0,67	low_impact	-1,39	medium_impact	0,56	medium_impact	-0,69	0,34	0,8	25,49	24,04	N	0,35	N	0,32	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10928	10928	T	C	MI.16685	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	169	57	S	P	Tcc/Ccc	-2,48	0	0	probably_damaging	0,98	neutral	0,06	neutral	1,44	neutral	-2,97	neutral	-2,1	medium_impact	2,35	damaging	0,59	damaging	0,16	deleterious	2,48	19,31	0,06	0,35	NA	NA	disease	0,56	neutral	0,5	disease	0,52	0	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,76	low_impact	-2,31	medium_impact	-0,47	medium_impact	1,2	0,23	0,8	25,49	24,04	N	0,34	N	0,94	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10928	10928	T	A	MI.16686	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	169	57	S	T	Tcc/Acc	-2,48	0	0	probably_damaging	0,92	neutral	0,22	neutral	1,52	neutral	-0,76	neutral	-0,76	low_impact	1,65	neutral	0,75	neutral	0,49	deleterious	1,91	15,66	0,22	0,45	NA	NA	neutral	0,1	neutral	0,2	neutral	0,26	5	neutral	0,95	neutral	0,15	neutral	-2	deleterious	0,67	low_impact	-1,71	medium_impact	-0,11	medium_impact	0,51	0,41	0,8	25,49	24,04	N	0,48	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10929	10929	C	A	MI.16687	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	170	57	S	Y	tCc/tAc	2,6	0,44	0	probably_damaging	0,94	neutral	0,41	neutral	1,45	neutral	-2,63	neutral	0,1	medium_impact	2,35	neutral	0,8	neutral	0,51	neutral	1,35	12,51	0,09	0,35	NA	NA	neutral	0,29	neutral	0,33	neutral	0,16	7	neutral	0,94	neutral	0,24	deleterious	1	deleterious	0,72	low_impact	-1,84	medium_impact	0,11	medium_impact	1,2	0,2	0,8	25,49	24,04	N	0,4	N	0,77	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10929	10929	C	G	MI.16688	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	170	57	S	C	tCc/tGc	2,6	0,44	0	probably_damaging	0,99	neutral	0,06	neutral	1,43	deleterious	-3,78	neutral	-1,27	medium_impact	2,35	neutral	0,77	damaging	0,19	deleterious	2,17	17,31	0,12	0,4	NA	NA	neutral	0,39	disease	0,53	neutral	0,33	3	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,71	low_impact	-2,59	medium_impact	-0,47	medium_impact	1,2	0,21	0,8	25,49	24,04	N	0,38	N	0,55	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10929	10929	C	T	MI.16689	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	170	57	S	F	tCc/tTc	2,6	0,44	0	benign	0,23	neutral	0,52	neutral	1,48	neutral	-1,58	neutral	1,16	neutral_impact	-0,24	neutral	0,77	neutral	0,95	neutral	1,39	12,72	0,1	0,4	NA	NA	neutral	0,22	neutral	0,23	neutral	0,16	7	neutral	0,37	deleterious	0,65	neutral	-6	deleterious	0,7	medium_impact	-0,23	medium_impact	0,22	low_impact	-1,36	0,13	0,8	25,49	24,04	N	0,32	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8471	8471	C	A	MI.1669	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	106	36	P	T	Cct/Act	-2,42	0	0	benign	0,04	neutral	0,55	neutral	2,01	neutral	0,08	neutral	-0,65	neutral_impact	0,28	neutral	0,97	neutral	0,95	deleterious	0,05	3,11	0,40256048	0,85	neutral	0,25	neutral	0,14	neutral	0,32	neutral	0,11	8	neutral	0,4	deleterious	0,76	neutral	-6	neutral	0,15	medium_impact	0,55	medium_impact	0,34	medium_impact	-0,86	0,48	0,85	19,12	8,87	N	0,34	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10931	10931	T	G	MI.16690	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	172	58	S	A	Tcc/Gcc	-5,93	0	0	possibly_damaging	0,53	neutral	0,43	neutral	1,57	neutral	1,31	neutral	-1,16	low_impact	1,48	neutral	0,76	neutral	0,96	deleterious	2,34	18,43	0,24	0,45	NA	NA	neutral	0,08	neutral	0,19	neutral	0,22	6	neutral	0,57	neutral	0,45	neutral	-3	deleterious	0,66	medium_impact	-0,77	medium_impact	0,13	medium_impact	0,34	0,38	0,8	21,13	19,5	N	0,5	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10931	10931	T	C	MI.16691	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	172	58	S	P	Tcc/Ccc	-5,93	0	0	benign	0,08	neutral	0,15	neutral	1,48	neutral	-2,04	deleterious	-2,6	medium_impact	2,63	neutral	0,64	neutral	0,39	deleterious	3,83	23,4	0,07	0,35	NA	NA	neutral	0,49	disease	0,55	disease	0,65	3	neutral	0,83	deleterious	0,54	neutral	-3	deleterious	0,75	medium_impact	0,28	medium_impact	-0,22	medium_impact	1,48	0,28	0,8	21,13	19,5	N	0,43	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10931	10931	T	A	MI.16692	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	172	58	S	T	Tcc/Acc	-5,93	0	0	possibly_damaging	0,78	neutral	0,8	neutral	1,6	neutral	-0,15	neutral	-0,04	neutral_impact	0,06	neutral	0,72	neutral	1	neutral	0,95	10,37	0,24	0,45	NA	NA	neutral	0,03	neutral	0,24	neutral	0,19	6	neutral	0,74	deleterious	0,51	neutral	-3	deleterious	0,66	low_impact	-1,23	medium_impact	0,54	low_impact	-1,07	0,43	0,8	21,13	19,5	N	0,43	N	0,61	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10932	10932	C	A	MI.16693	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	173	58	S	Y	tCc/tAc	-0,17	0	0	possibly_damaging	0,87	neutral	0,84	neutral	1,53	neutral	-0,85	deleterious	-3,11	medium_impact	2,63	neutral	0,79	neutral	0,56	deleterious	3,86	23,5	0,08	0,35	NA	NA	neutral	0,25	disease	0,51	neutral	0,25	5	neutral	0,85	deleterious	0,49	NA	0	deleterious	0,7	low_impact	-1,49	medium_impact	0,61	medium_impact	1,48	0,22	0,8	21,13	19,5	N	0,26	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10932	10932	C	T	MI.16694	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	173	58	S	F	tCc/tTc	-0,17	0	0	benign	0,11	neutral	0,73	neutral	1,52	neutral	0	deleterious	-3,03	low_impact	1,94	neutral	0,77	neutral	0,51	deleterious	4,04	23,7	0,09	0,35	NA	NA	neutral	0,28	neutral	0,37	neutral	0,16	7	neutral	0,16	deleterious	0,81	neutral	-6	deleterious	0,7	medium_impact	0,14	medium_impact	0,44	medium_impact	0,79	0,14	0,8	21,13	19,5	N	0,24	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10932	10932	C	G	MI.16695	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	173	58	S	C	tCc/tGc	-0,17	0	0	probably_damaging	0,98	neutral	0,3	neutral	1,52	neutral	-1,9	neutral	-2,4	medium_impact	2,28	neutral	0,78	neutral	0,41	deleterious	3,43	23	0,08	0,35	NA	NA	neutral	0,28	disease	0,56	neutral	0,34	3	neutral	0,98	neutral	0,16	deleterious	1	deleterious	0,69	low_impact	-2,31	medium_impact	0	medium_impact	1,13	0,23	0,8	21,13	19,5	N	0,35	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10934	10934	G	T	MI.16696	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	175	59	D	Y	Gac/Tac	-15,85	0	0	probably_damaging	1	deleterious	0	neutral	-0,16	deleterious	-9,14	deleterious	-6,83	high_impact	3,57	damaging	0,58	damaging	0,14	deleterious	3,75	23,3	0,02	0,35	NA	NA	disease	0,73	disease	0,86	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,41	0,1	0,8	47,28	9,34	N	0,34	N	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10934	10934	G	C	MI.16697	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	175	59	D	H	Gac/Cac	-15,85	0	0	probably_damaging	0,99	deleterious	0	neutral	-0,16	deleterious	-7,93	deleterious	-5,35	high_impact	3,57	damaging	0,59	damaging	0,14	deleterious	3,51	23,1	0,03	0,35	NA	NA	disease	0,66	disease	0,89	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,59	low_impact	-1,48	high_impact	2,41	0,31	0,8	47,28	9,34	N	0,35	N	0,99	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10934	10934	G	A	MI.16698	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	175	59	D	N	Gac/Aac	-15,85	0	0	probably_damaging	0,97	neutral	0,07	neutral	-0,11	deleterious	-5,72	deleterious	-3,83	high_impact	3,57	damaging	0,54	damaging	0,17	deleterious	4,05	23,7	0,16	0,45	NA	NA	disease	0,52	disease	0,8	disease	0,72	4	deleterious	0,99	neutral	0,05	deleterious	2	deleterious	0,79	low_impact	-2,14	medium_impact	-0,43	high_impact	2,41	0,55	0,8	47,28	9,34	N	0,41	N	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10935	10935	A	T	MI.16699	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	176	59	D	V	gAc/gTc	5,13	1	0	probably_damaging	0,98	deleterious	0	neutral	-0,16	deleterious	-8,48	deleterious	-6,75	high_impact	3,57	damaging	0,57	damaging	0,15	deleterious	4,24	23,9	0,02	0,35	NA	NA	disease	0,7	disease	0,84	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,31	low_impact	-1,48	high_impact	2,41	0,11	0,8	47,28	9,34	P	0,56	P	0,99	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8604	8604	T	A	MI.167	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	78	26	F	L	ttT/ttA	3,83	0,39	0	benign	0	neutral	1	neutral	4,49	neutral	0,67	neutral	-1,96	neutral_impact	-0,38	neutral	0,96	neutral	0,92	neutral	-0,3	0,66	0,42	0,65	neutral	0,29	neutral	0,15	neutral	0,27	neutral	0,22	6	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,09	high_impact	1,98	low_impact	-1,42	0,39	0,9	15,49	8,03	N	0,36	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8471	8471	C	G	MI.1670	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	106	36	P	A	Cct/Gct	-2,42	0	0	benign	0,02	neutral	0,62	neutral	1,98	neutral	-0,31	neutral	-1,55	low_impact	1,77	neutral	0,99	neutral	0,88	neutral	-0,82	0,04	0,38800886	0,85	neutral	0,18	neutral	0,06	neutral	0,41	neutral	0,04	9	neutral	0,35	deleterious	0,8	neutral	-6	neutral	0,14	medium_impact	0,85	medium_impact	0,41	medium_impact	0,42	0,4	0,85	19,12	8,87	N	0,43	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10935	10935	A	G	MI.16700	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	176	59	D	G	gAc/gGc	5,13	1	0	probably_damaging	0,97	deleterious	0	neutral	-0,13	deleterious	-6,31	deleterious	-5,36	medium_impact	3,22	damaging	0,58	damaging	0,17	deleterious	4,44	24,2	0,04	0,35	NA	NA	disease	0,63	disease	0,84	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-2,14	low_impact	-1,48	high_impact	2,06	0,28	0,8	47,28	9,34	P	0,57	P	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10935	10935	A	C	MI.16701	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	176	59	D	A	gAc/gCc	5,13	1	0	probably_damaging	0,94	deleterious	0	neutral	-0,14	deleterious	-6,73	deleterious	-6,09	high_impact	3,57	neutral	0,66	damaging	0,17	deleterious	4,06	23,7	0,03	0,35	NA	NA	disease	0,52	disease	0,84	disease	0,77	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,79	low_impact	-1,84	low_impact	-1,48	high_impact	2,41	0,28	0,8	47,28	9,34	P	0,59	P	0,93	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10936	10936	C	G	MI.16702	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	177	59	D	E	gaC/gaG	6,75	1	0	benign	0,3	deleterious	0	neutral	-0,08	deleterious	-5,17	deleterious	-3,06	high_impact	3,57	neutral	0,61	damaging	0,17	deleterious	3,74	23,3	0,06	0,35	NA	NA	neutral	0,48	disease	0,85	disease	0,71	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,78	medium_impact	-0,37	low_impact	-1,48	high_impact	2,41	0,31	0,8	47,28	9,34	P	0,64	P	0,95	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10936	10936	C	A	MI.16703	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	177	59	D	E	gaC/gaA	6,75	1	0	benign	0,3	deleterious	0	neutral	-0,08	deleterious	-5,17	deleterious	-3,06	high_impact	3,57	neutral	0,61	damaging	0,17	deleterious	4,06	23,7	0,06	0,35	NA	NA	neutral	0,48	disease	0,85	disease	0,71	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,78	medium_impact	-0,37	low_impact	-1,48	high_impact	2,41	0,31	0,8	47,28	9,34	P	0,64	P	0,95	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10937	10937	C	A	MI.16704	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	178	60	P	T	Ccc/Acc	-0,17	0	0	possibly_damaging	0,52	neutral	0,61	neutral	1,61	neutral	-0,56	deleterious	-2,69	medium_impact	2,15	neutral	0,8	neutral	0,4	deleterious	3,64	23,2	0,18	0,45	NA	NA	neutral	0,12	neutral	0,35	neutral	0,25	5	neutral	0,45	deleterious	0,55	NA	0	deleterious	0,68	medium_impact	-0,75	medium_impact	0,31	medium_impact	1	0,52	0,8	18,52	15,16	N	0,26	N	0,35	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10937	10937	C	T	MI.16705	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	178	60	P	S	Ccc/Tcc	-0,17	0	0	probably_damaging	0,94	neutral	0,78	neutral	1,68	neutral	-0,31	neutral	-1,96	low_impact	0,82	neutral	0,76	neutral	0,97	deleterious	2,08	16,7	0,19	0,45	NA	NA	neutral	0,1	neutral	0,29	neutral	0,22	6	neutral	0,93	neutral	0,42	neutral	-2	deleterious	0,68	low_impact	-1,84	medium_impact	0,51	medium_impact	-0,32	0,18	0,8	18,52	15,16	N	0,34	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10937	10937	C	G	MI.16706	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	178	60	P	A	Ccc/Gcc	-0,17	0	0	possibly_damaging	0,9	neutral	0,8	neutral	1,6	neutral	-0,47	deleterious	-2,5	medium_impact	3,04	neutral	0,78	neutral	0,88	deleterious	2,84	21,6	0,17	0,45	NA	NA	neutral	0,08	neutral	0,47	neutral	0,21	6	neutral	0,88	neutral	0,45	NA	0	deleterious	0,68	low_impact	-1,61	medium_impact	0,54	medium_impact	1,88	0,64	0,8	18,52	15,16	N	0,35	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10938	10938	C	T	MI.16707	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	179	60	P	L	cCc/cTc	-0,86	0	0	probably_damaging	0,96	neutral	0,79	neutral	1,62	neutral	-1,58	deleterious	-4,26	medium_impact	2,49	neutral	0,76	neutral	0,32	deleterious	4,21	23,9	0,15	0,4	NA	NA	neutral	0,22	neutral	0,47	neutral	0,19	6	neutral	0,95	neutral	0,42	deleterious	1	deleterious	0,7	low_impact	-2,01	medium_impact	0,52	medium_impact	1,34	0,64	0,8	18,52	15,16	N	0,24	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10938	10938	C	G	MI.16708	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	179	60	P	R	cCc/cGc	-0,86	0	0	probably_damaging	0,98	neutral	0,54	neutral	1,58	neutral	-0,94	deleterious	-3,37	medium_impact	3,04	neutral	0,7	damaging	0,2	deleterious	3,49	23,1	0,09	0,35	NA	NA	neutral	0,33	disease	0,64	neutral	0,39	2	deleterious	0,98	neutral	0,28	deleterious	1	deleterious	0,72	low_impact	-2,31	medium_impact	0,24	medium_impact	1,88	0,4	0,8	18,52	15,16	N	0,26	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10938	10938	C	A	MI.16709	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	179	60	P	H	cCc/cAc	-0,86	0	0	probably_damaging	1	neutral	0,57	neutral	1,56	neutral	-1,92	deleterious	-3,03	medium_impact	2,23	neutral	0,81	neutral	0,47	deleterious	3,85	23,4	0,1	0,4	NA	NA	neutral	0,25	neutral	0,5	neutral	0,19	6	deleterious	0,99	neutral	0,29	deleterious	1	deleterious	0,7	low_impact	-3,54	medium_impact	0,27	medium_impact	1,08	0,29	0,8	18,52	15,16	N	0,26	N	0,93	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8472	8472	C	T	MI.1671	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	107	36	P	L	cCt/cTt	-4,27	0	0,01	benign	0,02	neutral	0,33	neutral	1,92	neutral	-2,03	deleterious	-2,98	medium_impact	2,12	neutral	0,99	neutral	0,53	deleterious	0,16	4,2	0,52090386	0,85	neutral	0,29	neutral	0,14	neutral	0,41	neutral	0,1	8	neutral	0,66	deleterious	0,66	neutral	-3	neutral	0,16	medium_impact	0,85	medium_impact	0,12	medium_impact	0,72	0,73	0,85	19,12	8,87	N	0,55	P	0,75	polymorphism	1	0,06	rs879209186	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10940	10940	C	G	MI.16710	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	181	61	L	V	Cta/Gta	-6,16	0	0	probably_damaging	1	neutral	0,28	neutral	1,28	neutral	-2,99	neutral	-2,18	medium_impact	2,56	neutral	0,7	damaging	0,2	deleterious	3,26	22,8	0,25	0,45	NA	NA	neutral	0,15	neutral	0,45	neutral	0,21	6	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,69	low_impact	-3,54	medium_impact	-0,03	medium_impact	1,41	0,5	0,8	45,53	8,4	N	0,36	N	0,89	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10940	10940	C	A	MI.16711	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	181	61	L	M	Cta/Ata	-6,16	0	0	probably_damaging	1	neutral	0,25	neutral	1,23	deleterious	-3,88	neutral	-1,5	medium_impact	3,02	neutral	0,69	damaging	0,16	deleterious	3,6	23,2	0,25	0,45	NA	NA	neutral	0,13	neutral	0,46	neutral	0,21	6	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,69	low_impact	-3,54	medium_impact	-0,07	medium_impact	1,86	0,7	0,85	45,53	8,4	N	0,4	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10941	10941	T	C	MI.16712	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	182	61	L	P	cTa/cCa	-2,24	0	0	probably_damaging	1	deleterious	0	neutral	1,14	deleterious	-6,55	deleterious	-5,3	medium_impact	3,37	neutral	0,61	damaging	0,11	deleterious	3,76	23,3	0,02	0,35	NA	NA	disease	0,55	disease	0,76	disease	0,74	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,8	low_impact	-3,54	low_impact	-1,48	high_impact	2,21	0,3	0,8	45,53	8,4	N	0,34	N	0,98	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10941	10941	T	A	MI.16713	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	182	61	L	Q	cTa/cAa	-2,24	0	0	probably_damaging	1	deleterious	0,01	neutral	1,14	deleterious	-6,15	deleterious	-4,56	medium_impact	3,37	neutral	0,69	damaging	0,12	deleterious	3,93	23,5	0,02	0,35	NA	NA	neutral	0,48	disease	0,66	disease	0,53	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,74	low_impact	-3,54	medium_impact	-0,92	high_impact	2,21	0,32	0,8	45,53	8,4	N	0,34	N	0,99	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10941	10941	T	G	MI.16714	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	182	61	L	R	cTa/cGa	-2,24	0	0	probably_damaging	1	deleterious	0,01	neutral	1,14	deleterious	-6	deleterious	-4,57	medium_impact	3,37	neutral	0,63	damaging	0,11	deleterious	4,01	23,6	0,02	0,35	NA	NA	disease	0,58	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,54	medium_impact	-0,92	high_impact	2,21	0,14	0,8	45,53	8,4	N	0,36	N	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10943	10943	A	T	MI.16715	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	184	62	T	S	Aca/Tca	-0,86	0,05	0	benign	0,02	neutral	1	neutral	2,94	neutral	5,4	neutral	1,88	neutral_impact	-1,59	neutral	0,76	neutral	0,89	neutral	-1,54	0	0,32	0,5	NA	NA	neutral	0,03	neutral	0,28	neutral	0,14	7	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,09	medium_impact	0,87	high_impact	1,88	low_impact	-2,7	0,42	0,8	24,18	26,75	N	0,32	N	0	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10943	10943	A	G	MI.16716	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	184	62	T	A	Aca/Gca	-0,86	0,05	0	benign	0,02	deleterious	0,03	neutral	1,63	neutral	0,91	neutral	-0,24	low_impact	1,15	neutral	0,75	neutral	0,8	neutral	1,43	12,96	0,24	0,45	NA	NA	neutral	0,16	neutral	0,47	neutral	0,21	6	neutral	0,97	deleterious	0,51	neutral	-2	neutral	0,23	medium_impact	0,87	medium_impact	-0,64	medium_impact	0,01	0,24	0,8	24,18	26,75	N	0,47	N	0	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10943	10943	A	C	MI.16717	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	184	62	T	P	Aca/Cca	-0,86	0,05	0	possibly_damaging	0,72	deleterious	0	neutral	1,55	neutral	-1,61	neutral	-1,75	low_impact	1,7	neutral	0,62	neutral	0,47	deleterious	3,04	22,4	0,06	0,35	NA	NA	disease	0,59	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,68	low_impact	-1,1	low_impact	-1,48	medium_impact	0,56	0,32	0,8	24,18	26,75	N	0,37	N	0,39	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10944	10944	C	T	MI.16718	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	185	62	T	M	aCa/aTa	3,06	0,99	0	probably_damaging	0,94	deleterious	0	neutral	1,54	neutral	-2,75	neutral	-1,75	low_impact	1,7	neutral	0,73	neutral	0,55	deleterious	3,76	23,3	0,06	0,35	NA	NA	neutral	0,33	disease	0,58	neutral	0,35	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,7	low_impact	-1,84	low_impact	-1,48	medium_impact	0,56	0,56	0,8	24,18	26,75	P	0,58	P	0,48	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10944	10944	C	A	MI.16719	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	185	62	T	K	aCa/aAa	3,06	0,99	0	possibly_damaging	0,44	deleterious	0	neutral	1,56	neutral	-0,97	neutral	-1,05	low_impact	1,7	neutral	0,68	neutral	0,56	deleterious	2,63	20,4	0,07	0,35	NA	NA	neutral	0,39	disease	0,67	neutral	0,35	3	deleterious	1	neutral	0,28	deleterious	1	neutral	0,39	medium_impact	-0,62	low_impact	-1,48	medium_impact	0,56	0,37	0,8	24,18	26,75	P	0,58	P	0,44	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8472	8472	C	A	MI.1672	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	107	36	P	H	cCt/cAt	-4,27	0	0,01	benign	0	neutral	0,16	neutral	1,92	neutral	-1,89	neutral	-0,41	low_impact	1,77	neutral	1	neutral	0,9	deleterious	0,09	3,52	0,40896277	0,85	neutral	0,31	neutral	0,16	neutral	0,44	neutral	0,13	7	neutral	0,84	deleterious	0,58	neutral	-6	neutral	0,16	high_impact	2,09	medium_impact	-0,12	medium_impact	0,42	0,4	0,85	19,12	8,87	N	0,5	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10946	10946	A	T	MI.16720	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	187	63	T	S	Acc/Tcc	-9,39	0	0	benign	0,18	neutral	0,44	neutral	1,6	neutral	0,15	neutral	-0,97	low_impact	0,84	neutral	0,7	neutral	0,92	neutral	1,73	14,57	0,35	0,5	NA	NA	neutral	0,07	neutral	0,34	neutral	0,17	7	neutral	0,47	deleterious	0,63	neutral	-6	deleterious	0,67	medium_impact	-0,1	medium_impact	0,14	medium_impact	-0,3	0,69	0,85	20,7	16,72	N	0,44	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10946	10946	A	C	MI.16721	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	187	63	T	P	Acc/Ccc	-9,39	0	0	probably_damaging	0,97	neutral	0,19	neutral	1,46	deleterious	-3,02	deleterious	-3,22	medium_impact	2,92	neutral	0,67	neutral	0,36	deleterious	3,81	23,4	0,07	0,35	NA	NA	disease	0,63	disease	0,73	disease	0,75	5	deleterious	0,98	neutral	0,11	deleterious	1	deleterious	0,76	low_impact	-2,14	medium_impact	-0,15	medium_impact	1,76	0,45	0,8	20,7	16,72	N	0,33	N	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10946	10946	A	G	MI.16722	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	187	63	T	A	Acc/Gcc	-9,39	0	0	benign	0,12	neutral	0,51	neutral	1,63	neutral	0,42	neutral	-1,95	neutral_impact	0,64	neutral	0,76	neutral	0,99	deleterious	2,46	19,2	0,38	0,5	NA	NA	neutral	0,08	neutral	0,37	neutral	0,2	6	neutral	0,41	deleterious	0,7	neutral	-6	deleterious	0,67	medium_impact	0,1	medium_impact	0,21	medium_impact	-0,49	0,36	0,8	20,7	16,72	N	0,39	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10947	10947	C	T	MI.16723	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	188	63	T	I	aCc/aTc	-0,86	0	0	probably_damaging	0,94	neutral	0,4	neutral	1,55	neutral	-0,43	deleterious	-3,46	medium_impact	2,03	neutral	0,72	neutral	0,6	deleterious	3,77	23,4	0,18	0,45	NA	NA	neutral	0,38	neutral	0,47	neutral	0,19	6	neutral	0,94	neutral	0,23	deleterious	1	deleterious	0,71	low_impact	-1,84	medium_impact	0,1	medium_impact	0,88	0,6	0,8	20,7	16,72	N	0,34	N	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10947	10947	C	G	MI.16724	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	188	63	T	S	aCc/aGc	-0,86	0	0	benign	0,18	neutral	0,44	neutral	1,6	neutral	0,15	neutral	-0,97	low_impact	0,84	neutral	0,7	neutral	0,92	neutral	1,42	12,87	0,35	0,5	NA	NA	neutral	0,07	neutral	0,34	neutral	0,17	7	neutral	0,47	deleterious	0,63	neutral	-6	deleterious	0,67	medium_impact	-0,1	medium_impact	0,14	medium_impact	-0,3	0,69	0,85	20,7	16,72	N	0,47	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10947	10947	C	A	MI.16725	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	188	63	T	N	aCc/aAc	-0,86	0	0	possibly_damaging	0,88	neutral	0,3	neutral	1,48	neutral	-2,27	neutral	-2,34	medium_impact	2,58	neutral	0,71	neutral	0,51	deleterious	3,64	23,2	0,3	0,45	NA	NA	neutral	0,44	disease	0,63	neutral	0,43	1	neutral	0,9	neutral	0,21	NA	0	deleterious	0,71	low_impact	-1,53	medium_impact	0	medium_impact	1,43	0,52	0,8	20,7	16,72	N	0,39	N	0,39	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10949	10949	C	A	MI.16726	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	190	64	P	T	Ccc/Acc	-5,01	0	0	possibly_damaging	0,76	neutral	0,38	neutral	1,34	neutral	-0,48	deleterious	-6,12	high_impact	3,55	neutral	0,66	neutral	0,43	deleterious	3,57	23,2	0,18	0,45	NA	NA	neutral	0,42	disease	0,65	neutral	0,4	2	neutral	0,77	neutral	0,31	deleterious	1	deleterious	0,72	low_impact	-1,19	medium_impact	0,08	high_impact	2,39	0,6	0,8	46,41	8,92	N	0,4	N	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10949	10949	C	T	MI.16727	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	190	64	P	S	Ccc/Tcc	-5,01	0	0	possibly_damaging	0,76	neutral	0,41	neutral	1,36	neutral	-1,05	deleterious	-6,12	high_impact	3,55	neutral	0,73	neutral	0,52	deleterious	3,76	23,3	0,21	0,45	NA	NA	neutral	0,47	disease	0,64	neutral	0,41	2	neutral	0,76	neutral	0,33	deleterious	1	deleterious	0,74	low_impact	-1,19	medium_impact	0,11	high_impact	2,39	0,25	0,8	46,41	8,92	N	0,39	N	0,71	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10949	10949	C	G	MI.16728	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	190	64	P	A	Ccc/Gcc	-5,01	0	0	benign	0,08	neutral	0,5	neutral	1,36	neutral	-0,21	deleterious	-6,12	high_impact	3,55	neutral	0,69	neutral	0,5	deleterious	2,97	22,1	0,19	0,45	NA	NA	neutral	0,32	disease	0,61	neutral	0,37	3	neutral	0,43	deleterious	0,71	neutral	-2	deleterious	0,72	medium_impact	0,28	medium_impact	0,2	high_impact	2,39	0,62	0,8	46,41	8,92	N	0,42	N	0,77	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10950	10950	C	G	MI.16729	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	191	64	P	R	cCc/cGc	5,6	1	0	probably_damaging	0,93	neutral	0,34	neutral	1,3	neutral	-2,67	deleterious	-6,89	high_impact	3,55	neutral	0,73	neutral	0,44	deleterious	3,51	23,1	0,06	0,35	NA	NA	disease	0,71	disease	0,78	disease	0,74	5	neutral	0,94	neutral	0,21	deleterious	2	deleterious	0,78	low_impact	-1,77	medium_impact	0,04	high_impact	2,39	0,54	0,8	46,41	8,92	P	0,66	P	0,58	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8472	8472	C	G	MI.1673	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	107	36	P	R	cCt/cGt	-4,27	0	0,01	benign	0	neutral	0,44	neutral	2,11	neutral	1,08	neutral	-1,51	medium_impact	2,81	neutral	0,99	neutral	0,43	deleterious	-0,05	2,14	0,42878708	0,85	neutral	0,26	neutral	0,19	disease	0,51	neutral	0,12	8	neutral	0,56	deleterious	0,72	neutral	-3	neutral	0,16	high_impact	2,09	medium_impact	0,23	medium_impact	1,31	0,39	0,85	19,12	8,87	N	0,41	N	0,52	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10950	10950	C	A	MI.16730	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	191	64	P	H	cCc/cAc	5,6	1	0	probably_damaging	0,98	neutral	0,53	neutral	1,28	deleterious	-3,22	deleterious	-6,89	high_impact	3,55	neutral	0,68	neutral	0,36	deleterious	3,88	23,5	0,09	0,35	NA	NA	disease	0,66	disease	0,72	disease	0,71	4	neutral	0,97	neutral	0,28	deleterious	2	deleterious	0,77	low_impact	-2,31	medium_impact	0,23	high_impact	2,39	0,41	0,8	46,41	8,92	P	0,56	P	0,7	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10950	10950	C	T	MI.16731	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	191	64	P	L	cCc/cTc	5,6	1	0	benign	0,08	neutral	0,69	neutral	1,36	neutral	0,82	deleterious	-7,65	medium_impact	3,2	neutral	0,62	neutral	0,44	deleterious	4,28	24	0,14	0,4	NA	NA	disease	0,64	disease	0,64	disease	0,59	2	neutral	0,21	deleterious	0,81	neutral	-3	deleterious	0,75	medium_impact	0,28	medium_impact	0,4	high_impact	2,04	0,57	0,8	46,41	8,92	P	0,59	P	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10952	10952	C	G	MI.16732	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	193	65	L	V	Ctc/Gtc	-11,24	0	0	possibly_damaging	0,86	deleterious	0	neutral	0,03	deleterious	-5,5	neutral	-2,29	high_impact	3,57	damaging	0,56	neutral	0,51	deleterious	3,3	22,9	0,26	0,45	NA	NA	neutral	0,24	disease	0,66	neutral	0,39	2	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,73	low_impact	-1,46	low_impact	-1,48	high_impact	2,41	0,44	0,8	46,41	9,4	P	0,48	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10952	10952	C	A	MI.16733	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	193	65	L	I	Ctc/Atc	-11,24	0	0	possibly_damaging	0,86	deleterious	0,04	neutral	0,06	deleterious	-5,03	neutral	-1,52	high_impact	3,57	damaging	0,58	neutral	0,55	deleterious	3,94	23,5	0,21	0,45	NA	NA	neutral	0,28	disease	0,65	neutral	0,39	2	neutral	0,98	neutral	0,09	deleterious	5	deleterious	0,73	low_impact	-1,46	medium_impact	-0,57	high_impact	2,41	0,55	0,8	46,41	9,4	P	0,51	P	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10952	10952	C	T	MI.16734	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	193	65	L	F	Ctc/Ttc	-11,24	0	0	benign	0,29	neutral	0,1	neutral	0,04	deleterious	-5,38	deleterious	-3	high_impact	3,57	neutral	0,61	neutral	0,59	deleterious	3,79	23,4	0,22	0,45	NA	NA	neutral	0,3	disease	0,58	neutral	0,37	3	neutral	0,88	neutral	0,41	neutral	-2	deleterious	0,74	medium_impact	-0,35	medium_impact	-0,33	high_impact	2,41	0,33	0,8	46,41	9,4	P	0,49	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10953	10953	T	G	MI.16735	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	194	65	L	R	cTc/cGc	-0,17	0	0	probably_damaging	0,98	deleterious	0	neutral	-0,02	deleterious	-8,58	deleterious	-4,57	high_impact	3,57	damaging	0,58	neutral	0,37	deleterious	4,06	23,7	0,02	0,35	NA	NA	disease	0,64	disease	0,76	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,31	low_impact	-1,48	high_impact	2,41	0,12	0,8	46,41	9,4	N	0,45	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10953	10953	T	C	MI.16736	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	194	65	L	P	cTc/cCc	-0,17	0	0	probably_damaging	0,99	deleterious	0	neutral	-0,02	deleterious	-7,93	deleterious	-5,34	high_impact	3,57	damaging	0,55	neutral	0,44	deleterious	3,77	23,4	0,02	0,35	NA	NA	neutral	0,5	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,59	low_impact	-1,48	high_impact	2,41	0,27	0,8	46,41	9,4	N	0,39	N	0,98	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10953	10953	T	A	MI.16737	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	194	65	L	H	cTc/cAc	-0,17	0	0	probably_damaging	0,99	deleterious	0	neutral	-0,03	deleterious	-9,3	deleterious	-5,32	high_impact	3,57	damaging	0,56	neutral	0,39	deleterious	3,99	23,6	0,04	0,35	NA	NA	disease	0,56	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,59	low_impact	-1,48	high_impact	2,41	0,23	0,8	46,41	9,4	N	0,4	N	0,96	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10955	10955	C	A	MI.16738	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	196	66	L	M	Cta/Ata	-11,01	0	0	probably_damaging	0,97	neutral	0,12	neutral	1,39	neutral	-1,83	neutral	-1,25	medium_impact	2,61	neutral	0,79	neutral	0,35	deleterious	3,52	23,1	0,27	0,45	NA	NA	neutral	0,15	neutral	0,34	neutral	0,22	6	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,7	low_impact	-2,14	medium_impact	-0,28	medium_impact	1,46	0,46	0,8	20,7	19,59	N	0,42	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10955	10955	C	G	MI.16739	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	196	66	L	V	Cta/Gta	-11,01	0	0	benign	0,17	neutral	0,22	neutral	1,55	neutral	-0,2	neutral	-1,84	medium_impact	3,07	neutral	0,83	neutral	0,61	deleterious	3,22	22,7	0,25	0,45	NA	NA	neutral	0,12	neutral	0,35	neutral	0,24	5	neutral	0,74	deleterious	0,53	neutral	-3	deleterious	0,69	medium_impact	-0,07	medium_impact	-0,11	medium_impact	1,91	0,35	0,8	20,7	19,59	N	0,49	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8474	8474	C	G	MI.1674	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	109	37	P	A	Ccc/Gcc	-0,1	0	0	probably_damaging	0,99	neutral	0,25	neutral	1,83	deleterious	-3,26	deleterious	-5,57	medium_impact	2,88	neutral	1	neutral	0,73	deleterious	1,88	15,48	0,60038707	0,85	disease	0,76	neutral	0,05	disease	0,58	neutral	0,08	8	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,76	low_impact	-2,65	medium_impact	0,02	medium_impact	1,37	0,64	0,85	NA	NA	P	0,55	P	0,64	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10956	10956	T	C	MI.16740	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	197	66	L	P	cTa/cCa	-1,55	0	0	probably_damaging	0,99	deleterious	0	neutral	1,32	deleterious	-4,4	deleterious	-5,04	medium_impact	3,42	neutral	0,65	damaging	0,13	deleterious	3,78	23,4	0,05	0,35	NA	NA	disease	0,53	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-2,59	low_impact	-1,48	high_impact	2,26	0,26	0,8	20,7	19,59	N	0,31	N	0,86	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10956	10956	T	A	MI.16741	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	197	66	L	Q	cTa/cAa	-1,55	0	0	probably_damaging	0,99	deleterious	0	neutral	1,32	deleterious	-4	deleterious	-4,32	medium_impact	3,42	neutral	0,73	damaging	0,14	deleterious	3,95	23,6	0,06	0,35	NA	NA	neutral	0,44	disease	0,58	neutral	0,42	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,72	low_impact	-2,59	low_impact	-1,48	high_impact	2,26	0,2	0,8	20,7	19,59	N	0,36	N	0,91	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10956	10956	T	G	MI.16742	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	197	66	L	R	cTa/cGa	-1,55	0	0	probably_damaging	0,98	deleterious	0	neutral	1,32	deleterious	-3,84	deleterious	-4,38	medium_impact	3,42	neutral	0,65	damaging	0,12	deleterious	4,02	23,6	0,04	0,35	NA	NA	disease	0,58	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-2,31	low_impact	-1,48	high_impact	2,26	0,16	0,8	20,7	19,59	N	0,33	N	0,98	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10958	10958	A	T	MI.16743	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	199	67	M	L	Ata/Tta	-3,63	0	0	benign	0,08	neutral	0,93	neutral	1,77	neutral	2,55	neutral	0,15	neutral_impact	0,41	neutral	0,79	neutral	0,8	deleterious	3,15	22,6	0,16	0,45	NA	NA	neutral	0,14	neutral	0,37	neutral	0,23	5	neutral	0,02	deleterious	0,93	neutral	-6	deleterious	0,47	medium_impact	0,28	medium_impact	0,83	medium_impact	-0,72	0,23	0,8	19,61	20,92	N	0,3	N	0,3	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10958	10958	A	G	MI.16744	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	199	67	M	V	Ata/Gta	-3,63	0	0	benign	0,08	neutral	1	neutral	1,71	neutral	1,73	neutral	1,14	neutral_impact	-1,02	neutral	0,67	neutral	0,98	neutral	-0,14	1,47	0,16	0,45	NA	NA	neutral	0,03	neutral	0,31	neutral	0,16	7	neutral	0,08	deleterious	0,96	neutral	-6	deleterious	0,51	medium_impact	0,28	high_impact	1,88	low_impact	-2,14	0,24	0,8	19,61	20,92	N	0,36	N	0,31	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10958	10958	A	C	MI.16745	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	199	67	M	L	Ata/Cta	-3,63	0	0	benign	0,08	neutral	0,93	neutral	1,77	neutral	2,55	neutral	0,15	neutral_impact	0,41	neutral	0,79	neutral	0,8	deleterious	3,05	22,4	0,16	0,45	NA	NA	neutral	0,14	neutral	0,37	neutral	0,23	5	neutral	0,02	deleterious	0,93	neutral	-6	deleterious	0,47	medium_impact	0,28	medium_impact	0,83	medium_impact	-0,72	0,23	0,8	19,61	20,92	N	0,3	N	0,3	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10959	10959	T	C	MI.16746	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	200	67	M	T	aTa/aCa	0,29	0	0	benign	0,01	neutral	0,15	neutral	1,57	neutral	-0,22	neutral	-1,2	neutral_impact	-0,41	neutral	0,73	neutral	0,99	neutral	1,59	13,77	0,1	0,4	NA	NA	neutral	0,11	neutral	0,38	neutral	0,23	5	neutral	0,85	deleterious	0,57	neutral	-6	deleterious	0,62	medium_impact	1,16	medium_impact	-0,22	low_impact	-1,53	0,18	0,8	19,61	20,92	N	0,51	P	0,02	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10959	10959	T	A	MI.16747	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	200	67	M	K	aTa/aAa	0,29	0	0	benign	0,27	deleterious	0,02	neutral	1,5	neutral	-1,79	deleterious	-2,71	low_impact	1,38	neutral	0,65	neutral	0,49	deleterious	3,96	23,6	0,04	0,35	NA	NA	neutral	0,33	disease	0,62	neutral	0,37	3	neutral	0,98	neutral	0,38	neutral	-2	deleterious	0,69	medium_impact	-0,31	medium_impact	-0,75	medium_impact	0,24	0,21	0,8	19,61	20,92	N	0,37	N	0,79	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10960	10960	A	T	MI.16748	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	201	67	M	I	atA/atT	0,06	0	0	benign	0,03	neutral	0,88	neutral	1,73	neutral	1,13	neutral	1,28	neutral_impact	-0,9	neutral	0,7	neutral	0,98	deleterious	0,67	8,66	0,19	0,45	NA	NA	neutral	0,05	neutral	0,28	neutral	0,12	8	neutral	0,06	deleterious	0,93	neutral	-6	deleterious	0,58	medium_impact	0,7	medium_impact	0,69	low_impact	-2,02	0,22	0,8	19,61	20,92	N	0,36	N	0,09	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10960	10960	A	C	MI.16749	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	201	67	M	I	atA/atC	0,06	0	0	benign	0,03	neutral	0,88	neutral	1,73	neutral	1,13	neutral	1,28	neutral_impact	-0,9	neutral	0,7	neutral	0,98	deleterious	0,63	8,33	0,19	0,45	NA	NA	neutral	0,05	neutral	0,28	neutral	0,12	8	neutral	0,06	deleterious	0,93	neutral	-6	deleterious	0,58	medium_impact	0,7	medium_impact	0,69	low_impact	-2,02	0,22	0,8	19,61	20,92	N	0,35	N	0,09	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8474	8474	C	T	MI.1675	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	109	37	P	S	Ccc/Tcc	-0,1	0	0	probably_damaging	1	neutral	0,37	neutral	2,05	deleterious	-3,41	deleterious	-5,23	medium_impact	2,88	neutral	1	neutral	0,6	deleterious	3,87	23,5	0,60673599	0,85	disease	0,79	neutral	0,17	disease	0,57	neutral	0,2	6	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,16	medium_impact	1,37	0,38	0,85	NA	NA	N	0,53	P	0,65	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10961	10961	C	G	MI.16750	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	202	68	L	V	Cta/Gta	-10,32	0	0	possibly_damaging	0,86	deleterious	0,04	neutral	-0,39	deleterious	-6,15	neutral	-2,3	high_impact	3,56	damaging	0,51	neutral	0,51	deleterious	3,27	22,8	0,22	0,45	NA	NA	neutral	0,21	disease	0,67	neutral	0,38	2	neutral	0,98	neutral	0,09	deleterious	5	deleterious	0,75	low_impact	-1,46	medium_impact	-0,57	high_impact	2,4	0,33	0,8	45,75	8,94	P	0,51	P	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10961	10961	C	A	MI.16751	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	202	68	L	M	Cta/Ata	-10,32	0	0	possibly_damaging	0,68	neutral	0,09	neutral	-0,39	deleterious	-6,03	neutral	-1,53	medium_impact	2,87	damaging	0,51	neutral	0,61	deleterious	3,59	23,2	0,18	0,45	NA	NA	neutral	0,24	disease	0,6	neutral	0,37	3	neutral	0,92	neutral	0,21	NA	0	deleterious	0,73	low_impact	-1,03	medium_impact	-0,36	medium_impact	1,71	0,33	0,8	45,75	8,94	P	0,48	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10962	10962	T	G	MI.16752	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	203	68	L	R	cTa/cGa	-1,78	0	0	probably_damaging	0,98	deleterious	0	neutral	-0,45	deleterious	-9,42	deleterious	-4,59	high_impact	3,56	damaging	0,53	neutral	0,38	deleterious	4,02	23,6	0,03	0,35	NA	NA	disease	0,61	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,31	low_impact	-1,48	high_impact	2,4	0,09	0,8	45,75	8,94	N	0,48	N	1	polymorphism	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10962	10962	T	C	MI.16753	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	203	68	L	P	cTa/cCa	-1,78	0	0	probably_damaging	0,99	deleterious	0	neutral	-0,45	deleterious	-9,9	deleterious	-5,36	high_impact	3,56	damaging	0,48	neutral	0,45	deleterious	3,81	23,4	0,03	0,35	NA	NA	neutral	0,46	disease	0,79	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,59	low_impact	-1,48	high_impact	2,4	0,28	0,8	45,75	8,94	N	0,48	N	0,98	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10962	10962	T	A	MI.16754	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	203	68	L	Q	cTa/cAa	-1,78	0	0	probably_damaging	0,98	deleterious	0	neutral	-0,45	deleterious	-9,34	deleterious	-4,59	high_impact	3,56	damaging	0,52	neutral	0,44	deleterious	4,04	23,7	0,04	0,35	NA	NA	neutral	0,49	disease	0,68	disease	0,58	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,31	low_impact	-1,48	high_impact	2,4	0,19	0,8	45,75	8,94	N	0,46	N	0,99	polymorphism	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10964	10964	A	C	MI.16755	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	205	69	T	P	Act/Cct	-3,63	0	0	probably_damaging	0,94	deleterious	0,04	neutral	1,23	deleterious	-4,56	deleterious	-4,2	medium_impact	3,41	neutral	0,67	neutral	0,37	deleterious	3,35	22,9	0,06	0,35	NA	NA	disease	0,68	disease	0,75	disease	0,75	5	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,79	low_impact	-1,84	medium_impact	-0,57	high_impact	2,25	0,29	0,8	16,99	20,84	N	0,4	N	0,97	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10964	10964	A	T	MI.16756	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	205	69	T	S	Act/Tct	-3,63	0	0	benign	0,2	neutral	1	neutral	2,31	neutral	1,96	neutral	-2,39	low_impact	1,65	neutral	0,73	neutral	0,75	deleterious	1,81	15,03	0,37	0,5	NA	NA	neutral	0,03	neutral	0,32	neutral	0,14	7	neutral	0,2	deleterious	0,9	neutral	-6	deleterious	0,67	medium_impact	-0,15	high_impact	1,88	medium_impact	0,51	0,34	0,8	16,99	20,84	N	0,34	N	0,39	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10964	10964	A	G	MI.16757	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	205	69	T	A	Act/Gct	-3,63	0	0	possibly_damaging	0,64	deleterious	0	neutral	1,3	neutral	-2,27	deleterious	-3,33	medium_impact	3,06	neutral	0,76	neutral	0,72	deleterious	3,35	22,9	0,26	0,45	NA	NA	neutral	0,29	disease	0,6	neutral	0,39	2	deleterious	1	neutral	0,18	deleterious	4	deleterious	0,71	medium_impact	-0,95	low_impact	-1,48	medium_impact	1,9	0,23	0,8	16,99	20,84	N	0,45	N	0,86	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10965	10965	C	T	MI.16758	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	206	69	T	I	aCt/aTt	0,52	0,05	0	probably_damaging	0,96	deleterious	0	neutral	1,22	deleterious	-5,08	deleterious	-4,29	medium_impact	3,41	neutral	0,75	neutral	0,53	deleterious	3,71	23,3	0,15	0,4	NA	NA	disease	0,53	disease	0,58	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,75	low_impact	-2,01	low_impact	-1,48	high_impact	2,25	0,52	0,8	16,99	20,84	N	0,46	N	0,91	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10965	10965	C	G	MI.16759	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	206	69	T	S	aCt/aGt	0,52	0,05	0	benign	0,2	neutral	1	neutral	2,31	neutral	1,96	neutral	-2,39	low_impact	1,65	neutral	0,73	neutral	0,75	deleterious	1,94	15,84	0,37	0,5	NA	NA	neutral	0,03	neutral	0,32	neutral	0,14	7	neutral	0,2	deleterious	0,9	neutral	-6	deleterious	0,67	medium_impact	-0,15	high_impact	1,88	medium_impact	0,51	0,34	0,8	16,99	20,84	N	0,37	N	0,39	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8474	8474	C	A	MI.1676	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	109	37	P	T	Ccc/Acc	-0,1	0	0	probably_damaging	1	neutral	0,28	neutral	1,86	deleterious	-3,9	deleterious	-5,42	medium_impact	2,19	neutral	0,99	neutral	0,66	deleterious	2,62	20,3	0,66698427	0,85	disease	0,83	neutral	0,17	neutral	0,43	neutral	0,07	9	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,06	medium_impact	0,78	0,57	0,85	NA	NA	P	0,52	P	0,55	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10965	10965	C	A	MI.16760	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	206	69	T	N	aCt/aAt	0,52	0,05	0	possibly_damaging	0,83	deleterious	0,01	neutral	1,23	deleterious	-4,27	deleterious	-3,35	medium_impact	3,41	neutral	0,72	neutral	0,48	deleterious	3,57	23,1	0,3	0,45	NA	NA	disease	0,52	disease	0,64	disease	0,67	3	deleterious	0,99	neutral	0,09	deleterious	4	deleterious	0,74	low_impact	-1,37	medium_impact	-0,92	high_impact	2,25	0,39	0,8	16,99	20,84	N	0,44	N	0,83	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10967	10967	A	T	MI.16761	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	208	70	T	S	Acc/Tcc	-11,93	0	0	benign	0,27	neutral	0,07	neutral	1,55	neutral	-0,71	neutral	-1,05	medium_impact	2,29	neutral	0,82	neutral	0,83	deleterious	3,65	23,2	0,47	0,55	NA	NA	neutral	0,27	disease	0,52	neutral	0,32	4	neutral	0,92	neutral	0,4	neutral	-3	deleterious	0,7	medium_impact	-0,31	medium_impact	-0,43	medium_impact	1,14	0,4	0,8	33,33	28,4	N	0,45	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10967	10967	A	G	MI.16762	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	208	70	T	A	Acc/Gcc	-11,93	0	0	benign	0,01	neutral	0,39	neutral	1,62	neutral	0,47	neutral	-0,97	low_impact	1,32	neutral	0,75	neutral	0,97	deleterious	2,68	20,7	0,3	0,45	NA	NA	neutral	0,21	neutral	0,37	neutral	0,18	6	neutral	0,6	deleterious	0,69	neutral	-6	deleterious	0,7	medium_impact	1,16	medium_impact	0,09	medium_impact	0,18	0,26	0,8	33,33	28,4	N	0,43	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10967	10967	A	C	MI.16763	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	208	70	T	P	Acc/Ccc	-11,93	0	0	possibly_damaging	0,66	deleterious	0,03	neutral	1,51	neutral	-2,41	deleterious	-2,6	medium_impact	2,64	neutral	0,65	neutral	0,41	deleterious	3,83	23,4	0,06	0,35	NA	NA	disease	0,74	disease	0,7	disease	0,77	5	neutral	0,97	neutral	0,19	deleterious	4	deleterious	0,79	medium_impact	-0,99	medium_impact	-0,64	medium_impact	1,49	0,31	0,8	33,33	28,4	N	0,37	N	0,55	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10968	10968	C	G	MI.16764	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	209	70	T	S	aCc/aGc	0,29	0	0	benign	0,27	neutral	0,07	neutral	1,55	neutral	-0,71	neutral	-1,05	medium_impact	2,29	neutral	0,82	neutral	0,83	deleterious	3,34	22,9	0,47	0,55	NA	NA	neutral	0,27	disease	0,52	neutral	0,32	4	neutral	0,92	neutral	0,4	neutral	-3	deleterious	0,7	medium_impact	-0,31	medium_impact	-0,43	medium_impact	1,14	0,4	0,8	33,33	28,4	N	0,45	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10968	10968	C	T	MI.16765	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	209	70	T	I	aCc/aTc	0,29	0	0	benign	0,02	neutral	0,55	neutral	1,67	neutral	0,99	neutral	-1,74	medium_impact	1,95	neutral	0,76	neutral	0,79	deleterious	3,76	23,3	0,16	0,45	NA	NA	neutral	0,4	neutral	0,4	neutral	0,14	7	neutral	0,42	deleterious	0,77	neutral	-3	deleterious	0,73	medium_impact	0,87	medium_impact	0,25	medium_impact	0,8	0,44	0,8	33,33	28,4	N	0,32	N	0,09	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10968	10968	C	A	MI.16766	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	209	70	T	N	aCc/aAc	0,29	0	0	possibly_damaging	0,73	deleterious	0,03	neutral	1,52	neutral	-2,1	neutral	-2,3	medium_impact	2,64	neutral	0,68	neutral	0,58	deleterious	3,54	23,1	0,31	0,45	NA	NA	disease	0,54	disease	0,58	disease	0,71	4	neutral	0,98	neutral	0,15	deleterious	4	deleterious	0,74	low_impact	-1,12	medium_impact	-0,64	medium_impact	1,49	0,44	0,8	33,33	28,4	N	0,41	N	0,4	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10970	10970	T	C	MI.16767	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	211	71	W	R	Tga/Cga	-2,48	0	0	probably_damaging	0,97	deleterious	0	neutral	0,14	deleterious	-7,47	deleterious	-10,74	high_impact	3,54	damaging	0,57	damaging	0,06	deleterious	3,42	23	0,08	0,35	NA	NA	disease	0,75	disease	0,82	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-2,14	low_impact	-1,48	high_impact	2,38	0,17	0,8	47,28	9,24	N	0,4	N	0,97	polymorphism	1	0,23	.	.	.	.	.	pancreatic cancer cell line	.	.	.	.	.	.	.	.	.
chrM	10970	10970	T	G	MI.16768	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	211	71	W	G	Tga/Gga	-2,48	0	0	possibly_damaging	0,81	deleterious	0	neutral	0,13	deleterious	-8,07	deleterious	-9,97	high_impact	3,54	damaging	0,53	damaging	0,09	deleterious	3,81	23,4	0,1	0,4	NA	NA	disease	0,61	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	5	deleterious	0,77	low_impact	-1,31	low_impact	-1,48	high_impact	2,38	0,2	0,8	47,28	9,24	N	0,38	N	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10971	10971	G	T	MI.16769	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	212	71	W	L	tGa/tTa	5,6	1	0	probably_damaging	0,91	neutral	0,09	neutral	0,23	deleterious	-4,45	deleterious	-9,97	high_impact	3,54	damaging	0,52	damaging	0,06	deleterious	4,12	23,8	0,11	0,4	NA	NA	disease	0,64	disease	0,74	disease	0,72	4	neutral	0,97	neutral	0,09	deleterious	2	deleterious	0,78	low_impact	-1,66	medium_impact	-0,36	high_impact	2,38	0,13	0,8	47,28	9,24	P	0,58	P	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8475	8475	C	T	MI.1677	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	110	37	P	L	cCc/cTc	0,82	0	0	probably_damaging	1	neutral	0,17	neutral	1,85	deleterious	-4,7	deleterious	-6,83	medium_impact	2,58	neutral	0,99	neutral	0,67	deleterious	4,38	24,1	0,63281019	0,85	disease	0,87	neutral	0,21	neutral	0,45	neutral	0,16	7	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	-0,1	medium_impact	1,11	0,64	0,85	NA	NA	P	0,56	P	0,86	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10971	10971	G	C	MI.16770	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	212	71	W	S	tGa/tCa	5,6	1	0	benign	0,34	deleterious	0	neutral	0,14	deleterious	-7,27	deleterious	-10,74	high_impact	3,54	damaging	0,5	damaging	0,1	deleterious	3,89	23,5	0,08	0,35	NA	NA	disease	0,69	disease	0,76	disease	0,75	5	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,79	medium_impact	-0,45	low_impact	-1,48	high_impact	2,38	0,15	0,8	47,28	9,24	P	0,49	N	0,93	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10972	10972	A	T	MI.16771	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	213	71	W	C	tgA/tgT	9,05	1	0	probably_damaging	0,99	deleterious	0	neutral	0,13	deleterious	-8,81	deleterious	-9,97	high_impact	3,54	damaging	0,49	damaging	0,05	deleterious	4	23,6	0,1	0,4	NA	NA	disease	0,68	disease	0,8	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,59	low_impact	-1,48	high_impact	2,38	0,14	0,8	47,28	9,24	P	0,53	P	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10972	10972	A	C	MI.16772	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	213	71	W	C	tgA/tgC	9,05	1	0	probably_damaging	0,99	deleterious	0	neutral	0,13	deleterious	-8,81	deleterious	-9,97	high_impact	3,54	damaging	0,49	damaging	0,05	deleterious	3,87	23,5	0,1	0,4	NA	NA	disease	0,68	disease	0,8	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,59	low_impact	-1,48	high_impact	2,38	0,14	0,8	47,28	9,24	P	0,53	P	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10973	10973	C	T	MI.16773	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	214	72	L	F	Ctc/Ttc	1,44	1	0	benign	0,17	deleterious	0,01	neutral	0,91	deleterious	-4,78	deleterious	-3,06	medium_impact	3,5	neutral	0,66	neutral	0,62	deleterious	3,9	23,5	0,21	0,45	NA	NA	neutral	0,37	disease	0,62	neutral	0,39	2	deleterious	0,99	neutral	0,42	deleterious	1	deleterious	0,76	medium_impact	-0,07	medium_impact	-0,92	high_impact	2,34	0,33	0,8	47,28	9,32	P	0,52	P	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10973	10973	C	A	MI.16774	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	214	72	L	I	Ctc/Atc	1,44	1	0	benign	0,12	neutral	0,53	neutral	1,38	neutral	-0,62	neutral	-1,53	medium_impact	2,4	neutral	0,71	neutral	0,6	deleterious	3,96	23,6	0,21	0,45	NA	NA	neutral	0,13	neutral	0,42	neutral	0,22	6	neutral	0,38	deleterious	0,71	neutral	-3	deleterious	0,72	medium_impact	0,1	medium_impact	0,23	medium_impact	1,25	0,33	0,8	47,28	9,32	P	0,52	P	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10973	10973	C	G	MI.16775	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	214	72	L	V	Ctc/Gtc	1,44	1	0	possibly_damaging	0,52	neutral	0,12	neutral	1,09	neutral	-2,05	neutral	-2,3	medium_impact	3,15	neutral	0,72	neutral	0,52	deleterious	3,32	22,9	0,2	0,45	NA	NA	neutral	0,27	disease	0,65	neutral	0,38	2	neutral	0,87	neutral	0,3	NA	0	deleterious	0,74	medium_impact	-0,75	medium_impact	-0,28	medium_impact	1,99	0,41	0,8	47,28	9,32	P	0,61	P	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10974	10974	T	G	MI.16776	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	215	72	L	R	cTc/cGc	0,98	1	0	probably_damaging	0,97	deleterious	0	neutral	0,89	deleterious	-6,65	deleterious	-4,6	medium_impact	3,5	neutral	0,65	neutral	0,38	deleterious	4,11	23,7	0,04	0,35	NA	NA	disease	0,72	disease	0,77	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,84	low_impact	-2,14	low_impact	-1,48	high_impact	2,34	0,13	0,8	47,28	9,32	N	0,49	N	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10974	10974	T	A	MI.16777	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	215	72	L	H	cTc/cAc	0,98	1	0	probably_damaging	0,98	deleterious	0	neutral	0,89	deleterious	-7,37	deleterious	-5,37	medium_impact	3,5	neutral	0,69	neutral	0,4	deleterious	4,22	23,9	0,07	0,35	NA	NA	disease	0,59	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-2,31	low_impact	-1,48	high_impact	2,34	0,23	0,8	47,28	9,32	N	0,47	N	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10974	10974	T	C	MI.16778	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	215	72	L	P	cTc/cCc	0,98	1	0	probably_damaging	0,98	deleterious	0	neutral	0,89	deleterious	-7,02	deleterious	-5,37	medium_impact	3,5	neutral	0,64	neutral	0,44	deleterious	3,84	23,4	0,04	0,35	NA	NA	disease	0,63	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-2,31	low_impact	-1,48	high_impact	2,34	0,28	0,8	47,28	9,32	N	0,48	N	0,98	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10976	10976	C	G	MI.16779	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	217	73	L	V	Cta/Gta	-20	0	0,05	possibly_damaging	0,76	neutral	0,21	neutral	1,36	neutral	-1,39	neutral	-2,22	medium_impact	3,5	neutral	0,68	damaging	0,12	deleterious	3,29	22,8	0,33	0,5	NA	NA	neutral	0,29	neutral	0,5	neutral	0,19	6	neutral	0,86	neutral	0,23	NA	0	deleterious	0,73	low_impact	-1,19	medium_impact	-0,12	high_impact	2,34	0,31	0,8	45,97	8,88	N	0,37	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8475	8475	C	A	MI.1678	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	110	37	P	H	cCc/cAc	0,82	0	0	probably_damaging	1	neutral	0,05	neutral	1,78	deleterious	-5,42	deleterious	-6,25	high_impact	3,77	neutral	0,98	neutral	0,37	deleterious	4,01	23,6	0,44957237	0,85	disease	0,93	neutral	0,23	disease	0,61	neutral	0,16	7	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	-0,43	high_impact	2,13	0,63	0,85	NA	NA	P	0,53	P	0,82	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10976	10976	C	A	MI.16780	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	217	73	L	M	Cta/Ata	-20	0	0,05	probably_damaging	0,98	neutral	0,11	neutral	1,27	neutral	-2,55	neutral	-1,49	medium_impact	3,5	neutral	0,72	damaging	0,16	deleterious	3,62	23,2	0,24	0,45	NA	NA	neutral	0,29	neutral	0,49	neutral	0,19	6	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,71	low_impact	-2,31	medium_impact	-0,31	high_impact	2,34	0,36	0,8	45,97	8,88	N	0,42	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10977	10977	T	A	MI.16781	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	218	73	L	Q	cTa/cAa	0,29	0,02	0	probably_damaging	1	deleterious	0,03	neutral	1,22	deleterious	-4,19	deleterious	-4,49	medium_impact	3,5	neutral	0,68	damaging	0,12	deleterious	3,94	23,5	0,08	0,35	NA	NA	disease	0,59	disease	0,59	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,76	low_impact	-3,54	medium_impact	-0,64	high_impact	2,34	0,18	0,8	45,97	8,88	N	0,35	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10977	10977	T	C	MI.16782	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	218	73	L	P	cTa/cCa	0,29	0,02	0	probably_damaging	1	deleterious	0,02	neutral	1,22	deleterious	-4,64	deleterious	-5,24	medium_impact	3,5	damaging	0,58	damaging	0,12	deleterious	3,78	23,4	0,04	0,35	NA	NA	disease	0,68	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-3,54	medium_impact	-0,75	high_impact	2,34	0,28	0,8	45,97	8,88	N	0,3	N	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10977	10977	T	G	MI.16783	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	218	73	L	R	cTa/cGa	0,29	0,02	0	probably_damaging	1	deleterious	0,03	neutral	1,23	deleterious	-4,03	deleterious	-4,49	medium_impact	3,5	damaging	0,57	damaging	0,11	deleterious	4,07	23,7	0,05	0,35	NA	NA	disease	0,74	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,84	low_impact	-3,54	medium_impact	-0,64	high_impact	2,34	0,18	0,8	45,97	8,88	N	0,31	N	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10979	10979	C	G	MI.16784	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	220	74	P	A	Ccc/Gcc	-15,85	0	0	benign	0,12	neutral	0,24	neutral	1,37	neutral	-1,48	deleterious	-6,18	medium_impact	2,42	neutral	0,7	neutral	0,52	deleterious	2,95	22,1	0,22	0,45	NA	NA	neutral	0,42	disease	0,59	neutral	0,35	3	neutral	0,72	deleterious	0,56	neutral	-3	deleterious	0,75	medium_impact	0,1	medium_impact	-0,08	medium_impact	1,27	0,68	0,85	47,28	9,38	N	0,45	N	0,77	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10979	10979	C	A	MI.16785	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	220	74	P	T	Ccc/Acc	-15,85	0	0	possibly_damaging	0,83	neutral	0,15	neutral	1,31	neutral	-2,47	deleterious	-6,18	medium_impact	3,47	neutral	0,66	neutral	0,42	deleterious	3,56	23,1	0,22	0,45	NA	NA	disease	0,57	disease	0,64	disease	0,65	3	neutral	0,92	neutral	0,16	NA	0	deleterious	0,75	low_impact	-1,37	medium_impact	-0,22	high_impact	2,31	0,48	0,8	47,28	9,38	N	0,43	N	0,89	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10979	10979	C	T	MI.16786	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	220	74	P	S	Ccc/Tcc	-15,85	0	0	possibly_damaging	0,83	neutral	0,25	neutral	1,37	neutral	-1,52	deleterious	-6,18	medium_impact	2,57	neutral	0,68	neutral	0,48	deleterious	3,76	23,4	0,23	0,45	NA	NA	disease	0,52	disease	0,62	neutral	0,47	1	neutral	0,88	neutral	0,21	NA	0	deleterious	0,77	low_impact	-1,37	medium_impact	-0,07	medium_impact	1,42	0,13	0,8	47,28	9,38	N	0,42	N	0,71	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10980	10980	C	A	MI.16787	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	221	74	P	H	cCc/cAc	5,6	1	0	probably_damaging	0,98	neutral	0,15	neutral	1,26	deleterious	-4,17	deleterious	-6,95	medium_impact	3,47	neutral	0,65	neutral	0,35	deleterious	4	23,6	0,11	0,4	NA	NA	disease	0,75	disease	0,74	disease	0,74	5	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,8	low_impact	-2,31	medium_impact	-0,22	high_impact	2,31	0,3	0,8	47,28	9,38	P	0,6	P	0,7	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10980	10980	C	T	MI.16788	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	221	74	P	L	cCc/cTc	5,6	1	0	possibly_damaging	0,48	neutral	0,26	neutral	1,36	neutral	-1,68	deleterious	-7,72	medium_impact	3,12	neutral	0,66	neutral	0,43	deleterious	4,22	23,9	0,11	0,4	NA	NA	disease	0,73	disease	0,61	disease	0,57	1	neutral	0,71	neutral	0,39	NA	0	deleterious	0,79	medium_impact	-0,69	medium_impact	-0,05	medium_impact	1,96	0,52	0,8	47,28	9,38	P	0,67	P	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10980	10980	C	G	MI.16789	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	221	74	P	R	cCc/cGc	5,6	1	0	probably_damaging	0,96	neutral	0,09	neutral	1,28	deleterious	-3,36	deleterious	-6,95	medium_impact	3,47	neutral	0,64	neutral	0,42	deleterious	3,47	23,1	0,07	0,35	NA	NA	disease	0,79	disease	0,74	disease	0,75	5	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,84	low_impact	-2,01	medium_impact	-0,36	high_impact	2,31	0,37	0,8	47,28	9,38	P	0,61	P	0,58	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8475	8475	C	G	MI.1679	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	110	37	P	R	cCc/cGc	0,82	0	0	probably_damaging	1	neutral	0,19	neutral	1,79	deleterious	-4,32	deleterious	-6,43	high_impact	3,77	neutral	1	neutral	0,33	deleterious	3,59	23,2	0,50472207	0,85	disease	0,88	neutral	0,25	disease	0,63	neutral	0,15	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,06	high_impact	2,13	0,55	0,85	NA	NA	N	0,52	P	0,87	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10982	10982	C	T	MI.16790	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	223	75	L	F	Ctc/Ttc	-7,55	0	0	benign	0,17	deleterious	0	neutral	0,11	deleterious	-5,98	deleterious	-3	high_impact	3,52	neutral	0,63	neutral	0,45	deleterious	3,84	23,4	0,17	0,45	NA	NA	neutral	0,46	disease	0,67	neutral	0,45	1	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,77	medium_impact	-0,07	low_impact	-1,48	high_impact	2,36	0,54	0,8	47,06	9,34	N	0,43	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10982	10982	C	G	MI.16791	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	223	75	L	V	Ctc/Gtc	-7,55	0	0	possibly_damaging	0,74	neutral	0,07	neutral	0,16	deleterious	-4,81	neutral	-2,23	medium_impact	3,18	neutral	0,66	neutral	0,59	deleterious	3,32	22,9	0,25	0,45	NA	NA	neutral	0,38	disease	0,61	neutral	0,37	3	neutral	0,95	neutral	0,17	NA	0	deleterious	0,76	low_impact	-1,14	medium_impact	-0,43	high_impact	2,02	0,49	0,8	47,06	9,34	N	0,45	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10982	10982	C	A	MI.16792	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	223	75	L	I	Ctc/Atc	-7,55	0	0	possibly_damaging	0,74	neutral	0,12	neutral	0,19	deleterious	-4,42	neutral	-1,5	medium_impact	3,18	neutral	0,65	neutral	0,57	deleterious	3,96	23,6	0,33	0,5	NA	NA	neutral	0,43	disease	0,57	neutral	0,38	2	neutral	0,91	neutral	0,19	NA	0	deleterious	0,76	low_impact	-1,14	medium_impact	-0,28	high_impact	2,02	0,49	0,8	47,06	9,34	N	0,49	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10983	10983	T	A	MI.16793	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	224	75	L	H	cTc/cAc	-2,01	0	0	probably_damaging	0,98	deleterious	0	neutral	0,07	deleterious	-9,14	deleterious	-5,28	high_impact	3,52	neutral	0,62	neutral	0,38	deleterious	3,99	23,6	0,06	0,35	NA	NA	disease	0,68	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,31	low_impact	-1,48	high_impact	2,36	0,23	0,8	47,06	9,34	N	0,36	N	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10983	10983	T	C	MI.16794	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	224	75	L	P	cTc/cCc	-2,01	0	0	probably_damaging	0,97	deleterious	0	neutral	0,08	deleterious	-7,74	deleterious	-5,29	medium_impact	2,98	damaging	0,6	neutral	0,5	deleterious	3,79	23,4	0,04	0,35	NA	NA	disease	0,68	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,85	low_impact	-2,14	low_impact	-1,48	medium_impact	1,82	0,26	0,8	47,06	9,34	N	0,38	N	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10983	10983	T	G	MI.16795	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	224	75	L	R	cTc/cGc	-2,01	0	0	probably_damaging	0,96	deleterious	0	neutral	0,08	deleterious	-8,37	deleterious	-4,51	high_impact	3,52	neutral	0,65	neutral	0,36	deleterious	4,07	23,7	0,03	0,35	NA	NA	disease	0,77	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,87	low_impact	-2,01	low_impact	-1,48	high_impact	2,36	0,12	0,8	47,06	9,34	N	0,43	N	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10985	10985	A	G	MI.16796	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	226	76	T	A	Aca/Gca	-5,01	0	0	benign	0,07	neutral	0,05	neutral	1,56	neutral	-0,35	neutral	-0,46	low_impact	0,8	neutral	0,71	neutral	0,85	neutral	1,46	13,12	0,29	0,45	NA	NA	neutral	0,37	neutral	0,5	neutral	0,15	7	neutral	0,95	deleterious	0,49	neutral	-6	neutral	0,19	medium_impact	0,34	medium_impact	-0,52	medium_impact	-0,33	0,29	0,8	41,83	8,12	N	0,46	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10985	10985	A	C	MI.16797	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	226	76	T	P	Aca/Cca	-5,01	0	0	possibly_damaging	0,45	deleterious	0	neutral	1,48	neutral	-2,84	neutral	-1,24	low_impact	1,15	neutral	0,66	neutral	0,47	neutral	1,74	14,65	0,04	0,35	NA	NA	disease	0,82	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,58	medium_impact	-0,64	low_impact	-1,48	medium_impact	0,01	0,28	0,8	41,83	8,12	N	0,33	N	0,29	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10985	10985	A	T	MI.16798	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	226	76	T	S	Aca/Tca	-5,01	0	0	benign	0,2	neutral	0,1	neutral	1,55	neutral	-0,45	neutral	-0,37	neutral_impact	0,6	neutral	0,68	neutral	0,64	neutral	1,34	12,47	0,4	0,5	NA	NA	neutral	0,38	neutral	0,36	neutral	0,15	7	neutral	0,88	neutral	0,45	neutral	-6	neutral	0,24	medium_impact	-0,15	medium_impact	-0,33	medium_impact	-0,53	0,52	0,8	41,83	8,12	N	0,47	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10986	10986	C	A	MI.16799	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	227	76	T	K	aCa/aAa	8,59	1	0	benign	0,15	deleterious	0,01	neutral	1,5	neutral	-1,93	neutral	-0,56	low_impact	1,15	neutral	0,73	neutral	0,56	deleterious	2,51	19,5	0,07	0,35	NA	NA	disease	0,7	disease	0,68	disease	0,74	5	deleterious	0,99	neutral	0,43	neutral	-2	neutral	0,3	medium_impact	-0,01	medium_impact	-0,92	medium_impact	0,01	0,38	0,8	41,83	8,12	P	0,56	P	0,35	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8604	8604	T	G	MI.168	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	78	26	F	L	ttT/ttG	3,83	0,39	0	benign	0	neutral	1	neutral	4,49	neutral	0,67	neutral	-1,96	neutral_impact	-0,38	neutral	0,96	neutral	0,92	neutral	-0,42	0,34	0,42	0,65	neutral	0,29	neutral	0,15	neutral	0,27	neutral	0,22	6	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,09	high_impact	1,98	low_impact	-1,42	0,39	0,9	15,49	8,03	N	0,36	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8477	8477	T	A	MI.1680	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	112	38	S	T	Tca/Aca	-4,5	0	0	benign	0	neutral	0,85	neutral	1,6	neutral	0,28	neutral	-0,88	low_impact	0,82	neutral	1	neutral	0,94	deleterious	-0,06	2,07	0,74487615	0,85	neutral	0,31	neutral	0,21	neutral	0,22	neutral	0,24	5	neutral	0,15	deleterious	0,93	neutral	-6	neutral	0,14	high_impact	2,09	medium_impact	0,72	medium_impact	-0,4	0,75	0,85	20,59	7,81	N	0,35	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10986	10986	C	T	MI.16800	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	227	76	T	M	aCa/aTa	8,59	1	0	benign	0,01	neutral	1	neutral	2,05	neutral	2,53	neutral	3,51	neutral_impact	-2,36	neutral	0,71	neutral	0,94	neutral	-0,77	0,05	0,12	0,4	NA	NA	neutral	0,08	neutral	0,27	neutral	0,18	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,1	medium_impact	1,16	high_impact	1,88	low_impact	-3,46	0,51	0,8	41,83	8,12	N	0,51	P	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10988	10988	A	G	MI.16801	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	229	77	I	V	Atc/Gtc	1,68	0,91	0	benign	0,05	neutral	0,17	neutral	1,45	neutral	-0,77	neutral	-0,71	medium_impact	2,06	neutral	0,74	neutral	0,75	deleterious	2,86	21,7	0,52	0,6	NA	NA	neutral	0,13	neutral	0,42	neutral	0,23	5	neutral	0,82	deleterious	0,56	neutral	-3	deleterious	0,6	medium_impact	0,48	medium_impact	-0,18	medium_impact	0,91	0,38	0,8	27,02	20,05	P	0,52	P	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10988	10988	A	T	MI.16802	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	229	77	I	F	Atc/Ttc	1,68	0,91	0	possibly_damaging	0,88	neutral	0,19	neutral	1,34	neutral	-2,04	deleterious	-2,55	medium_impact	2,4	neutral	0,74	neutral	0,69	deleterious	3,8	23,4	0,17	0,45	NA	NA	neutral	0,46	disease	0,58	neutral	0,42	2	neutral	0,93	neutral	0,16	NA	0	deleterious	0,71	low_impact	-1,53	medium_impact	-0,15	medium_impact	1,25	0,43	0,8	27,02	20,05	N	0,47	N	0,57	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10988	10988	A	C	MI.16803	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	229	77	I	L	Atc/Ctc	1,68	0,91	0	benign	0,18	neutral	0,44	neutral	1,58	neutral	-0,03	neutral	-0,56	neutral_impact	0,22	neutral	0,74	neutral	0,96	deleterious	2,14	17,08	0,22	0,45	NA	NA	neutral	0,17	neutral	0,33	neutral	0,2	6	neutral	0,47	deleterious	0,63	neutral	-6	deleterious	0,62	medium_impact	-0,1	medium_impact	0,14	medium_impact	-0,91	0,46	0,8	27,02	20,05	N	0,42	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10989	10989	T	A	MI.16804	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	230	77	I	N	aTc/aAc	-0,17	0,61	0	probably_damaging	0,91	deleterious	0	neutral	1,27	deleterious	-4,21	deleterious	-4,78	medium_impact	2,95	neutral	0,66	neutral	0,49	deleterious	4,45	24,2	0,09	0,4	NA	NA	disease	0,62	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,74	low_impact	-1,66	low_impact	-1,48	medium_impact	1,79	0,14	0,8	27,02	20,05	N	0,38	N	0,92	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10989	10989	T	C	MI.16805	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	230	77	I	T	aTc/aCc	-0,17	0,61	0	benign	0,13	deleterious	0,01	neutral	1,32	neutral	-2,37	deleterious	-3,21	medium_impact	2,15	neutral	0,72	neutral	0,72	deleterious	2,27	17,99	0,12	0,4	NA	NA	neutral	0,34	disease	0,56	neutral	0,36	3	deleterious	0,99	neutral	0,44	deleterious	1	deleterious	0,7	medium_impact	0,06	medium_impact	-0,92	medium_impact	1	0,29	0,8	27,02	20,05	N	0,38	N	0,84	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10989	10989	T	G	MI.16806	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	230	77	I	S	aTc/aGc	-0,17	0,61	0	possibly_damaging	0,76	deleterious	0,01	neutral	1,3	neutral	-2,88	deleterious	-4,01	medium_impact	2,95	neutral	0,71	neutral	0,55	deleterious	4,15	23,8	0,04	0,35	NA	NA	disease	0,61	disease	0,62	disease	0,68	4	deleterious	0,99	neutral	0,13	deleterious	4	deleterious	0,73	low_impact	-1,19	medium_impact	-0,92	medium_impact	1,79	0,16	0,8	27,02	20,05	N	0,35	N	0,86	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10990	10990	C	A	MI.16807	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	231	77	I	M	atC/atA	7,44	0,98	0	benign	0,4	neutral	0,21	neutral	1,35	neutral	-1,84	neutral	-1,48	medium_impact	2,6	neutral	0,77	neutral	0,94	deleterious	2,64	20,4	0,3	0,45	NA	NA	neutral	0,23	neutral	0,4	neutral	0,17	7	neutral	0,75	neutral	0,41	neutral	-3	deleterious	0,69	medium_impact	-0,55	medium_impact	-0,12	medium_impact	1,45	0,49	0,8	27,02	20,05	P	0,63	P	0,19	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10990	10990	C	G	MI.16808	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	231	77	I	M	atC/atG	7,44	0,98	0	benign	0,4	neutral	0,21	neutral	1,35	neutral	-1,84	neutral	-1,48	medium_impact	2,6	neutral	0,77	neutral	0,94	deleterious	2,14	17,09	0,3	0,45	NA	NA	neutral	0,23	neutral	0,4	neutral	0,17	7	neutral	0,75	neutral	0,41	neutral	-3	deleterious	0,69	medium_impact	-0,55	medium_impact	-0,12	medium_impact	1,45	0,49	0,8	27,02	20,05	P	0,63	P	0,19	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10991	10991	A	C	MI.16809	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	232	78	M	L	Atg/Ctg	-10,78	0	0	benign	0,02	neutral	1	neutral	1,76	neutral	2,59	neutral	0,15	neutral_impact	0,27	neutral	0,66	neutral	0,98	neutral	-1,3	0,01	0,23	0,45	NA	NA	neutral	0,11	neutral	0,4	neutral	0,18	6	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,11	medium_impact	0,87	high_impact	1,88	medium_impact	-0,86	0,31	0,8	25,71	18,27	N	0,4	N	0,2	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8477	8477	T	G	MI.1681	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	112	38	S	A	Tca/Gca	-4,5	0	0	benign	0,01	neutral	0,7	neutral	1,66	neutral	1,36	neutral	-1,18	medium_impact	2,27	neutral	1	neutral	0,85	neutral	-0,37	0,45	0,72936886	0,85	neutral	0,24	neutral	0,09	neutral	0,35	neutral	0,04	9	neutral	0,28	deleterious	0,85	neutral	-3	neutral	0,14	medium_impact	1,14	medium_impact	0,5	medium_impact	0,85	0,69	0,85	20,59	7,81	N	0,42	N	0,22	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10991	10991	A	G	MI.16810	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	232	78	M	V	Atg/Gtg	-10,78	0	0	benign	0,25	neutral	0,08	neutral	1,48	neutral	1,67	neutral	-0,84	medium_impact	2,47	neutral	0,78	neutral	0,82	deleterious	0,8	9,48	0,2	0,45	NA	NA	neutral	0,39	disease	0,6	neutral	0,38	2	neutral	0,91	neutral	0,42	neutral	-3	neutral	0,15	medium_impact	-0,27	medium_impact	-0,39	medium_impact	1,32	0,23	0,8	25,71	18,27	N	0,42	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10991	10991	A	T	MI.16811	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	232	78	M	L	Atg/Ttg	-10,78	0	0	benign	0,02	neutral	1	neutral	1,76	neutral	2,59	neutral	0,15	neutral_impact	0,27	neutral	0,66	neutral	0,98	neutral	-1,32	0	0,23	0,45	NA	NA	neutral	0,11	neutral	0,4	neutral	0,18	6	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,11	medium_impact	0,87	high_impact	1,88	medium_impact	-0,86	0,31	0,8	25,71	18,27	N	0,39	N	0,2	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10992	10992	T	A	MI.16812	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	233	78	M	K	aTg/aAg	-0,86	0	0	benign	0,36	deleterious	0	neutral	1,38	neutral	-1,92	deleterious	-3,55	medium_impact	2,82	neutral	0,68	neutral	0,47	deleterious	2,1	16,87	0,03	0,35	NA	NA	disease	0,61	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,32	deleterious	1	neutral	0,3	medium_impact	-0,48	low_impact	-1,48	medium_impact	1,66	0,12	0,8	25,71	18,27	N	0,38	N	0,9	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10992	10992	T	C	MI.16813	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	233	78	M	T	aTg/aCg	-0,86	0	0	benign	0,02	neutral	0,07	neutral	1,44	neutral	-0,1	deleterious	-2,79	medium_impact	2,82	neutral	0,78	neutral	0,81	neutral	-0,15	1,4	0,11	0,4	NA	NA	neutral	0,41	disease	0,64	neutral	0,37	3	neutral	0,93	deleterious	0,53	neutral	-3	neutral	0,14	medium_impact	0,87	medium_impact	-0,43	medium_impact	1,66	0,11	0,8	25,71	18,27	N	0,44	N	0,75	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10993	10993	G	C	MI.16814	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	234	78	M	I	atG/atC	5,83	0,88	0	benign	0,25	neutral	0,22	neutral	1,53	neutral	2	neutral	-0,32	low_impact	1,5	neutral	0,71	neutral	0,99	neutral	-0,1	1,72	0,25	0,45	NA	NA	neutral	0,26	neutral	0,45	neutral	0,18	6	neutral	0,74	deleterious	0,49	neutral	-6	neutral	0,19	medium_impact	-0,27	medium_impact	-0,11	medium_impact	0,36	0,31	0,8	25,71	18,27	P	0,57	P	0,3	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10993	10993	G	T	MI.16815	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	234	78	M	I	atG/atT	5,83	0,88	0	benign	0,25	neutral	0,22	neutral	1,53	neutral	2	neutral	-0,32	low_impact	1,5	neutral	0,71	neutral	0,99	deleterious	0	2,58	0,25	0,45	NA	NA	neutral	0,26	neutral	0,45	neutral	0,18	6	neutral	0,74	deleterious	0,49	neutral	-6	neutral	0,19	medium_impact	-0,27	medium_impact	-0,11	medium_impact	0,36	0,31	0,8	25,71	18,27	P	0,57	P	0,3	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10994	10994	G	C	MI.16816	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	235	79	A	P	Gca/Cca	-3,86	0	0	probably_damaging	1	deleterious	0	neutral	0,18	deleterious	-7,05	deleterious	-3,86	high_impact	3,55	neutral	0,76	neutral	0,43	deleterious	3,7	23,3	0,04	0,35	NA	NA	disease	0,68	disease	0,81	disease	0,75	5	deleterious	1	deleterious	0	deleterious	6	deleterious	0,8	low_impact	-3,54	low_impact	-1,48	high_impact	2,39	0,38	0,8	46,84	9,23	N	0,45	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10994	10994	G	A	MI.16817	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	235	79	A	T	Gca/Aca	-3,86	0	0	probably_damaging	1	deleterious	0	neutral	0,21	deleterious	-5,59	deleterious	-3,09	high_impact	3,55	neutral	0,66	neutral	0,45	deleterious	4,11	23,7	0,12	0,4	NA	NA	disease	0,58	disease	0,71	disease	0,71	4	deleterious	1	deleterious	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	2,39	0,48	0,8	46,84	9,23	N	0,46	N	0,82	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10994	10994	G	T	MI.16818	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	235	79	A	S	Gca/Tca	-3,86	0	0	probably_damaging	1	neutral	0,26	neutral	0,42	deleterious	-3,12	neutral	-2,32	high_impact	3,55	neutral	0,66	neutral	0,54	deleterious	3,59	23,2	0,2	0,45	NA	NA	neutral	0,49	disease	0,65	neutral	0,41	2	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	-0,05	high_impact	2,39	0,27	0,8	46,84	9,23	N	0,5	N	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10995	10995	C	G	MI.16819	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	236	79	A	G	gCa/gGa	7,21	1	0	probably_damaging	1	deleterious	0,04	neutral	0,22	deleterious	-5,37	deleterious	-3,09	medium_impact	2,86	damaging	0,59	neutral	0,53	deleterious	3,82	23,4	0,2	0,45	NA	NA	neutral	0,49	disease	0,65	disease	0,63	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,77	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,7	0,46	0,8	46,84	9,23	P	0,59	P	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8477	8477	T	C	MI.1682	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	112	38	S	P	Tca/Cca	-4,5	0	0	benign	0,06	neutral	0,25	neutral	1,57	neutral	-0,71	neutral	-1,84	low_impact	1,28	neutral	1	neutral	0,69	deleterious	0,6	8,13	0,56663707	0,85	disease	0,5	neutral	0,34	neutral	0,2	neutral	0,21	6	neutral	0,73	deleterious	0,6	neutral	-6	neutral	0,21	medium_impact	0,38	medium_impact	0,02	medium_impact	0	0,42	0,85	20,59	7,81	N	0,52	P	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10995	10995	C	A	MI.16820	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	236	79	A	E	gCa/gAa	7,21	1	0	probably_damaging	1	deleterious	0	neutral	0,17	deleterious	-7,3	deleterious	-3,86	high_impact	3,55	neutral	0,73	neutral	0,43	deleterious	4,29	24	0,04	0,35	NA	NA	disease	0,7	disease	0,78	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	2,39	0,15	0,8	46,84	9,23	P	0,56	P	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10995	10995	C	T	MI.16821	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	236	79	A	V	gCa/gTa	7,21	1	0	probably_damaging	1	neutral	0,07	neutral	0,18	deleterious	-6,58	deleterious	-3,09	high_impact	3,55	damaging	0,59	neutral	0,51	deleterious	4,37	24,1	0,14	0,4	NA	NA	disease	0,59	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,78	low_impact	-3,54	medium_impact	-0,43	high_impact	2,39	0,49	0,8	46,84	9,23	P	0,62	P	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10997	10997	A	T	MI.16822	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	238	80	S	C	Agc/Tgc	-12,85	0	0	probably_damaging	0,99	deleterious	0	neutral	0,05	deleterious	-7,93	deleterious	-3,78	medium_impact	3,49	neutral	0,62	damaging	0,13	deleterious	3,38	23	0,06	0,35	NA	NA	disease	0,58	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,76	low_impact	-2,59	low_impact	-1,48	high_impact	2,33	0,39	0,8	16,56	16,09	N	0,33	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10997	10997	A	C	MI.16823	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	238	80	S	R	Agc/Cgc	-12,85	0	0	probably_damaging	0,97	deleterious	0	neutral	0,06	deleterious	-6,93	deleterious	-3,78	medium_impact	3,49	neutral	0,66	damaging	0,13	deleterious	3,75	23,3	0,04	0,35	NA	NA	disease	0,71	disease	0,81	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,82	low_impact	-2,14	low_impact	-1,48	high_impact	2,33	0,4	0,8	16,56	16,09	N	0,39	N	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10997	10997	A	G	MI.16824	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	238	80	S	G	Agc/Ggc	-12,85	0	0	possibly_damaging	0,89	neutral	0,06	neutral	0,08	deleterious	-6,11	deleterious	-3,06	medium_impact	3,49	neutral	0,66	damaging	0,24	deleterious	3,49	23,1	0,17	0,45	NA	NA	neutral	0,44	disease	0,74	disease	0,59	2	neutral	0,98	neutral	0,09	NA	0	deleterious	0,74	low_impact	-1,57	medium_impact	-0,47	high_impact	2,33	0,64	0,8	16,56	16,09	N	0,38	N	0,87	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10998	10998	G	C	MI.16825	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	239	80	S	T	aGc/aCc	6,75	1	0	benign	0,26	neutral	0,09	neutral	0,1	deleterious	-5,47	neutral	-2,13	medium_impact	2,59	damaging	0,56	damaging	0,2	deleterious	3,23	22,8	0,19	0,45	NA	NA	neutral	0,45	disease	0,68	neutral	0,43	2	neutral	0,89	neutral	0,42	neutral	-3	deleterious	0,75	medium_impact	-0,29	medium_impact	-0,36	medium_impact	1,44	0,64	0,8	16,56	16,09	P	0,65	P	0,73	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10998	10998	G	A	MI.16826	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	239	80	S	N	aGc/aAc	6,75	1	0	probably_damaging	0,91	deleterious	0	neutral	0,08	deleterious	-6	neutral	-2,26	medium_impact	3,15	neutral	0,62	damaging	0,16	deleterious	3,56	23,1	0,27	0,45	NA	NA	disease	0,55	disease	0,7	disease	0,66	3	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,77	low_impact	-1,66	low_impact	-1,48	medium_impact	1,99	0,45	0,8	16,56	16,09	P	0,59	P	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	10998	10998	G	T	MI.16827	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	239	80	S	I	aGc/aTc	6,75	1	0	probably_damaging	0,94	deleterious	0,02	neutral	0,06	deleterious	-7,42	deleterious	-4,53	medium_impact	3,49	neutral	0,62	damaging	0,18	deleterious	3,99	23,6	0,04	0,35	NA	NA	disease	0,79	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,8	low_impact	-1,84	medium_impact	-0,75	high_impact	2,33	0,29	0,8	16,56	16,09	P	0,53	P	1	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11000	11000	C	A	MI.16828	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	241	81	Q	K	Caa/Aaa	-1,09	0,01	0	probably_damaging	1	neutral	0,23	neutral	1,34	neutral	-1,9	deleterious	-3,08	medium_impact	3,11	neutral	0,63	damaging	0,16	deleterious	3,78	23,4	0,27	0,45	NA	NA	disease	0,55	disease	0,71	disease	0,67	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,09	medium_impact	1,95	0,25	0,8	46,84	9,35	N	0,36	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11000	11000	C	G	MI.16829	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	241	81	Q	E	Caa/Gaa	-1,09	0,01	0	probably_damaging	1	neutral	0,34	neutral	1,37	neutral	-1,48	neutral	-2,31	medium_impact	2,56	neutral	0,64	damaging	0,17	deleterious	2,93	22	0,36	0,5	NA	NA	neutral	0,36	disease	0,72	neutral	0,41	2	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,04	medium_impact	1,41	0,3	0,8	46,84	9,35	N	0,32	N	0,93	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8478	8478	C	G	MI.1683	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	113	38	S	W	tCa/tGa	-1,72	0	0	benign	0,43	neutral	0,21	neutral	1,55	neutral	-1,44	deleterious	-3,96	medium_impact	3,08	neutral	1	neutral	0,44	deleterious	2,63	20,4	0,43790363	0,85	disease	0,81	neutral	0,32	disease	0,55	neutral	0,23	6	neutral	0,76	neutral	0,39	neutral	-3	neutral	0,43	medium_impact	-0,64	medium_impact	-0,03	medium_impact	1,54	0,48	0,85	20,59	7,81	N	0,5	N	0,6	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11001	11001	A	G	MI.16830	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	242	81	Q	R	cAa/cGa	7,21	1	0	probably_damaging	1	neutral	0,18	neutral	1,3	neutral	-2,55	deleterious	-3,08	medium_impact	3,11	damaging	0,6	damaging	0,17	deleterious	3,36	22,9	0,25	0,45	NA	NA	disease	0,58	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,17	medium_impact	1,95	0,09	0,8	46,84	9,35	P	0,64	P	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11001	11001	A	T	MI.16831	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	242	81	Q	L	cAa/cTa	7,21	1	0	probably_damaging	1	neutral	0,33	neutral	1,3	neutral	-2,46	deleterious	-5,4	medium_impact	3,46	neutral	0,68	damaging	0,16	deleterious	3,73	23,3	0,1	0,4	NA	NA	disease	0,64	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,03	high_impact	2,3	0,06	0,8	46,84	9,35	P	0,64	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11001	11001	A	C	MI.16832	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	242	81	Q	P	cAa/cCa	7,21	1	0	probably_damaging	1	neutral	0,14	neutral	1,26	deleterious	-4,06	deleterious	-4,63	medium_impact	3,46	damaging	0,6	damaging	0,15	deleterious	3,2	22,7	0,06	0,35	NA	NA	disease	0,69	disease	0,8	disease	0,76	5	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,24	high_impact	2,3	0,26	0,8	46,84	9,35	P	0,65	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11002	11002	A	T	MI.16833	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	243	81	Q	H	caA/caT	8,59	1	0,02	probably_damaging	1	neutral	0,27	neutral	1,27	deleterious	-3,34	deleterious	-3,86	medium_impact	3,11	neutral	0,73	damaging	0,15	deleterious	3,47	23	0,3	0,45	NA	NA	disease	0,55	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,04	medium_impact	1,95	0,54	0,8	46,84	9,35	P	0,66	P	0,97	polymorphism	1	0,08	rs386829114	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11002	11002	A	C	MI.16834	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	243	81	Q	H	caA/caC	8,59	1	0,02	probably_damaging	1	neutral	0,27	neutral	1,27	deleterious	-3,34	deleterious	-3,86	medium_impact	3,11	neutral	0,73	damaging	0,15	deleterious	3,35	22,9	0,3	0,45	NA	NA	disease	0,55	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,04	medium_impact	1,95	0,54	0,8	46,84	9,35	P	0,66	P	0,97	polymorphism	1	0,08	rs386829114	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11003	11003	C	G	MI.16835	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	244	82	R	G	Cgc/Ggc	0,75	0,02	0	benign	0,15	neutral	0,26	neutral	1,58	neutral	-0,02	neutral	-0,61	neutral_impact	0	neutral	0,74	neutral	0,64	deleterious	2,16	17,24	0,13	0,4	NA	NA	neutral	0,23	disease	0,52	neutral	0,28	4	neutral	0,7	deleterious	0,56	neutral	-6	neutral	0,18	medium_impact	-0,01	medium_impact	-0,05	low_impact	-1,13	0,24	0,8	28,98	18,21	N	0,44	N	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11003	11003	C	A	MI.16836	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	244	82	R	S	Cgc/Agc	0,75	0,02	0	benign	0,11	neutral	0,42	neutral	1,7	neutral	1,42	neutral	0,41	neutral_impact	-0,9	neutral	0,74	neutral	0,95	neutral	1,55	13,57	0,12	0,4	NA	NA	neutral	0,15	neutral	0,35	neutral	0,23	5	neutral	0,51	deleterious	0,66	neutral	-6	neutral	0,17	medium_impact	0,14	medium_impact	0,12	low_impact	-2,02	0,17	0,8	28,98	18,21	N	0,4	N	0,3	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11003	11003	C	T	MI.16837	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	244	82	R	C	Cgc/Tgc	0,75	0,02	0	possibly_damaging	0,76	deleterious	0,01	neutral	1,52	deleterious	-3,51	neutral	-1,82	neutral_impact	0,34	neutral	0,68	neutral	0,31	deleterious	4,62	24,5	0,13	0,4	NA	NA	neutral	0,37	neutral	0,5	neutral	0,15	7	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,62	low_impact	-1,19	medium_impact	-0,92	medium_impact	-0,79	0,8	0,85	28,98	18,21	N	0,36	N	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11004	11004	G	A	MI.16838	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	245	82	R	H	cGc/cAc	-0,4	0	0	benign	0	neutral	0,09	neutral	1,57	neutral	-0,29	neutral	1,78	neutral_impact	-2,14	neutral	0,74	neutral	0,94	neutral	1,05	10,94	0,36	0,5	NA	NA	neutral	0,12	neutral	0,2	neutral	0,27	5	neutral	0,91	deleterious	0,55	neutral	-6	neutral	0,11	high_impact	2,1	medium_impact	-0,36	low_impact	-3,24	0,84	0,9	28,98	18,21	N	0,5	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11004	11004	G	C	MI.16839	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	245	82	R	P	cGc/cCc	-0,4	0	0	benign	0,36	neutral	0,09	neutral	1,53	neutral	-1,59	neutral	-1,22	neutral_impact	0	neutral	0,68	neutral	0,29	deleterious	2,32	18,32	0,03	0,35	NA	NA	disease	0,61	disease	0,7	disease	0,72	4	neutral	0,89	neutral	0,37	neutral	-6	neutral	0,38	medium_impact	-0,48	medium_impact	-0,36	low_impact	-1,13	0,13	0,8	28,98	18,21	N	0,3	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8478	8478	C	T	MI.1684	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	113	38	S	L	tCa/tTa	-1,72	0	0	benign	0	neutral	0,61	neutral	1,71	neutral	1,83	deleterious	-2,71	low_impact	1,28	neutral	1	neutral	0,82	neutral	1,15	11,49	0,71043795	0,85	neutral	0,37	neutral	0,19	neutral	0,29	neutral	0,08	8	neutral	0,39	deleterious	0,81	neutral	-6	neutral	0,14	high_impact	2,09	medium_impact	0,4	medium_impact	0	0,87	0,9	20,59	7,81	N	0,29	N	0,2	polymorphism	1	0,06	rs201902227	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11004	11004	G	T	MI.16840	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	245	82	R	L	cGc/cTc	-0,4	0	0	benign	0,07	deleterious	0,04	neutral	1,55	neutral	-0,92	neutral	-1,65	neutral_impact	0,34	neutral	0,82	neutral	0,48	deleterious	2,29	18,13	0,13	0,4	NA	NA	neutral	0,35	disease	0,53	neutral	0,32	4	neutral	0,96	deleterious	0,49	neutral	-2	neutral	0,2	medium_impact	0,34	medium_impact	-0,57	medium_impact	-0,79	0,01	0,8	28,98	18,21	N	0,4	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11006	11006	C	T	MI.16841	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	247	83	H	Y	Cac/Tac	-3,17	0	0	probably_damaging	1	neutral	1	neutral	1,39	neutral	2,31	deleterious	-4,64	medium_impact	3,07	neutral	0,67	damaging	0,12	deleterious	3,62	23,2	0,34	0,5	NA	NA	disease	0,58	disease	0,74	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,78	low_impact	-3,54	high_impact	1,88	medium_impact	1,91	0,14	0,8	47,49	9,4	N	0,3	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11006	11006	C	A	MI.16842	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	247	83	H	N	Cac/Aac	-3,17	0	0	probably_damaging	1	neutral	0,31	neutral	1,38	neutral	-0,7	deleterious	-5,41	medium_impact	3,42	neutral	0,69	damaging	0,16	deleterious	3,75	23,3	0,35	0,5	NA	NA	disease	0,55	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,01	high_impact	2,26	0,23	0,8	47,49	9,4	N	0,34	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11006	11006	C	G	MI.16843	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	247	83	H	D	Cac/Gac	-3,17	0	0	probably_damaging	1	neutral	0,2	neutral	1,37	neutral	-0,51	deleterious	-6,96	medium_impact	3,42	neutral	0,64	damaging	0,13	deleterious	3,71	23,3	0,06	0,35	NA	NA	disease	0,68	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,14	high_impact	2,26	0,26	0,8	47,49	9,4	N	0,38	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11007	11007	A	T	MI.16844	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	248	83	H	L	cAc/cTc	5,6	1	0	probably_damaging	1	neutral	0,67	neutral	1,51	neutral	-0,86	deleterious	-8,51	medium_impact	3,42	neutral	0,7	damaging	0,12	deleterious	3,72	23,3	0,08	0,35	NA	NA	disease	0,65	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,37	high_impact	2,26	0,12	0,8	47,49	9,4	N	0,55	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11007	11007	A	G	MI.16845	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	248	83	H	R	cAc/cGc	5,6	1	0	probably_damaging	1	neutral	0,37	neutral	1,39	neutral	-0,9	deleterious	-6,19	medium_impact	2,87	neutral	0,63	damaging	0,14	deleterious	2,87	21,7	0,19	0,45	NA	NA	disease	0,58	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	0,07	medium_impact	1,71	0,22	0,8	47,49	9,4	P	0,6	P	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11007	11007	A	C	MI.16846	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	248	83	H	P	cAc/cCc	5,6	1	0	probably_damaging	1	neutral	0,2	neutral	1,37	neutral	-1,79	deleterious	-7,73	medium_impact	3,42	neutral	0,72	damaging	0,13	deleterious	3,09	22,5	0,05	0,35	NA	NA	disease	0,75	disease	0,82	disease	0,8	6	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,14	high_impact	2,26	0,12	0,8	47,49	9,4	P	0,64	P	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11008	11008	C	G	MI.16847	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	249	83	H	Q	caC/caG	6,75	1	0	probably_damaging	1	neutral	0,29	neutral	1,39	neutral	-0,66	deleterious	-6,19	medium_impact	3,42	neutral	0,68	damaging	0,13	deleterious	3,48	23,1	0,24	0,45	NA	NA	disease	0,58	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,02	high_impact	2,26	0,26	0,8	47,49	9,4	P	0,65	P	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11008	11008	C	A	MI.16848	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	249	83	H	Q	caC/caA	6,75	1	0	probably_damaging	1	neutral	0,29	neutral	1,39	neutral	-0,66	deleterious	-6,19	medium_impact	3,42	neutral	0,68	damaging	0,13	deleterious	3,76	23,3	0,24	0,45	NA	NA	disease	0,58	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,02	high_impact	2,26	0,26	0,8	47,49	9,4	P	0,65	P	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11009	11009	T	A	MI.16849	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	250	84	L	M	Tta/Ata	-0,63	0	0	possibly_damaging	0,68	neutral	0,25	neutral	1,39	neutral	0,15	neutral	-0,73	low_impact	1,09	neutral	0,76	neutral	0,95	deleterious	2,07	16,68	0,29	0,45	NA	NA	neutral	0,09	neutral	0,19	neutral	0,25	5	neutral	0,79	neutral	0,29	neutral	-3	deleterious	0,7	low_impact	-1,03	medium_impact	-0,07	medium_impact	-0,05	0,5	0,8	14,81	15,64	P	0,52	P	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8480	8480	C	T	MI.1685	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	115	39	P	S	Cca/Tca	-1,95	0	0	probably_damaging	1	neutral	0,49	neutral	1,68	neutral	1,55	deleterious	-2,54	low_impact	0,89	neutral	1	neutral	0,93	deleterious	2,5	19,49	0,48647755	0,85	neutral	0,18	neutral	0,14	neutral	0,19	neutral	0,13	7	deleterious	0,99	neutral	0,25	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	0,28	medium_impact	-0,34	0,33	0,85	7,35	7,21	N	0,5	N	0,39	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11009	11009	T	G	MI.16850	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	250	84	L	V	Tta/Gta	-0,63	0	0	possibly_damaging	0,86	neutral	0,44	neutral	1,38	neutral	-0,93	neutral	-1,47	medium_impact	2,35	neutral	0,75	neutral	0,69	deleterious	2,2	17,5	0,28	0,45	NA	NA	neutral	0,26	neutral	0,48	neutral	0,2	6	neutral	0,85	neutral	0,29	NA	0	deleterious	0,72	low_impact	-1,46	medium_impact	0,14	medium_impact	1,2	0,31	0,8	14,81	15,64	N	0,45	N	0,66	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11010	11010	T	C	MI.16851	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	251	84	L	S	tTa/tCa	-1,32	0	0	probably_damaging	0,98	neutral	0,05	neutral	1,3	neutral	-2,83	deleterious	-3,68	medium_impact	2,55	neutral	0,74	neutral	0,52	deleterious	3,65	23,2	0,09	0,35	NA	NA	disease	0,52	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,77	low_impact	-2,31	medium_impact	-0,52	medium_impact	1,4	0,23	0,8	14,81	15,64	N	0,4	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11010	11010	T	G	MI.16852	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	251	84	L	W	tTa/tGa	-1,32	0	0	probably_damaging	0,99	deleterious	0,02	neutral	1,25	deleterious	-4,39	deleterious	-3,93	medium_impact	2,9	neutral	0,78	neutral	0,42	deleterious	3,68	23,3	0,11	0,4	NA	NA	disease	0,54	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,77	low_impact	-2,59	medium_impact	-0,75	medium_impact	1,74	0,22	0,8	14,81	15,64	N	0,37	N	0,89	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11011	11011	A	T	MI.16853	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	252	84	L	F	ttA/ttT	4,21	0,48	0	probably_damaging	0,96	neutral	0,23	neutral	1,33	neutral	-2,42	deleterious	-2,5	medium_impact	2,9	neutral	0,73	neutral	0,47	deleterious	3,49	23,1	0,27	0,45	NA	NA	neutral	0,33	disease	0,61	neutral	0,38	3	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,73	low_impact	-2,01	medium_impact	-0,09	medium_impact	1,74	0,31	0,8	14,81	15,64	N	0,48	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11011	11011	A	C	MI.16854	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	252	84	L	F	ttA/ttC	4,21	0,48	0	probably_damaging	0,96	neutral	0,23	neutral	1,33	neutral	-2,42	deleterious	-2,5	medium_impact	2,9	neutral	0,73	neutral	0,47	deleterious	3,4	23	0,27	0,45	NA	NA	neutral	0,33	disease	0,61	neutral	0,38	3	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,73	low_impact	-2,01	medium_impact	-0,09	medium_impact	1,74	0,31	0,8	14,81	15,64	N	0,47	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11012	11012	T	G	MI.16855	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	253	85	S	A	Tcc/Gcc	-3,63	0	0	benign	0,12	neutral	0,61	neutral	1,52	neutral	-0,45	neutral	-0,99	low_impact	1,24	neutral	0,72	neutral	0,98	neutral	-0,26	0,83	0,56	0,6	NA	NA	neutral	0,09	neutral	0,29	neutral	0,21	6	neutral	0,29	deleterious	0,75	neutral	-6	neutral	0,18	medium_impact	0,1	medium_impact	0,31	medium_impact	0,1	0,35	0,8	35,08	30,78	N	0,4	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11012	11012	T	C	MI.16856	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	253	85	S	P	Tcc/Ccc	-3,63	0	0	possibly_damaging	0,71	neutral	0,2	neutral	1,44	neutral	-2,44	neutral	-1,86	medium_impact	2,17	neutral	0,7	neutral	0,42	deleterious	2,44	19,09	0,22	0,45	NA	NA	disease	0,65	neutral	0,49	neutral	0,5	0	neutral	0,84	neutral	0,25	NA	0	deleterious	0,67	low_impact	-1,08	medium_impact	-0,14	medium_impact	1,02	0,17	0,8	35,08	30,78	N	0,38	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11012	11012	T	A	MI.16857	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	253	85	S	T	Tcc/Acc	-3,63	0	0	benign	0,3	neutral	0,45	neutral	1,51	neutral	-1,53	neutral	-0,84	low_impact	1,83	neutral	0,72	neutral	0,98	deleterious	0,08	3,39	0,59	0,65	NA	NA	neutral	0,12	neutral	0,19	neutral	0,25	5	neutral	0,46	deleterious	0,58	neutral	-6	neutral	0,31	medium_impact	-0,37	medium_impact	0,15	medium_impact	0,68	0,38	0,8	35,08	30,78	P	0,56	P	0,22	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11013	11013	C	A	MI.16858	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	254	85	S	Y	tCc/tAc	-5,24	0	0,01	benign	0,01	neutral	0,44	neutral	1,44	deleterious	-3,17	neutral	-2,03	low_impact	1,83	neutral	0,8	neutral	0,76	deleterious	0,26	5,26	0,24	0,45	NA	NA	neutral	0,4	neutral	0,41	neutral	0,15	7	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,11	medium_impact	1,16	medium_impact	0,14	medium_impact	0,68	0,15	0,8	35,08	30,78	N	0,33	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11013	11013	C	T	MI.16859	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	254	85	S	F	tCc/tTc	-5,24	0	0,01	benign	0,18	neutral	0,34	neutral	1,44	deleterious	-3,1	neutral	-2,39	medium_impact	2,52	neutral	0,75	neutral	0,56	deleterious	0,74	9,08	0,27	0,45	NA	NA	neutral	0,37	neutral	0,41	neutral	0,15	7	neutral	0,6	deleterious	0,58	neutral	-3	neutral	0,29	medium_impact	-0,1	medium_impact	0,04	medium_impact	1,37	0,07	0,8	35,08	30,78	N	0,43	N	0,73	polymorphism	1	0,07	rs879244441	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8480	8480	C	A	MI.1686	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	115	39	P	T	Cca/Aca	-1,95	0	0	probably_damaging	1	neutral	0,46	neutral	1,61	neutral	0,53	deleterious	-2,62	low_impact	1,46	neutral	0,97	neutral	0,94	neutral	1,67	14,25	0,57564883	0,85	neutral	0,26	neutral	0,1	neutral	0,2	neutral	0,05	9	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	0,25	medium_impact	0,15	0,66	0,85	7,35	7,21	N	0,41	N	0,1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11013	11013	C	G	MI.16860	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	254	85	S	C	tCc/tGc	-5,24	0	0,01	benign	0,02	neutral	0,1	neutral	1,42	deleterious	-4,99	neutral	-2,29	low_impact	1,43	neutral	0,78	neutral	0,72	deleterious	2,19	17,46	0,26	0,45	NA	NA	neutral	0,38	neutral	0,47	neutral	0,16	7	neutral	0,9	deleterious	0,54	neutral	-6	deleterious	0,64	medium_impact	0,87	medium_impact	-0,33	medium_impact	0,29	0,16	0,8	35,08	30,78	N	0,43	N	0,56	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11015	11015	A	C	MI.16861	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	256	86	S	R	Agt/Cgt	-8,24	0	0	benign	0,06	neutral	0,38	neutral	1,48	neutral	-0,77	neutral	-0,01	low_impact	1,7	neutral	0,76	neutral	0,54	deleterious	0,53	7,64	0,31	0,45	NA	NA	neutral	0,45	neutral	0,35	neutral	0,21	6	neutral	0,58	deleterious	0,66	neutral	-6	neutral	0,15	medium_impact	0,41	medium_impact	0,08	medium_impact	0,56	0,33	0,8	26,14	26,33	N	0,39	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11015	11015	A	T	MI.16862	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	256	86	S	C	Agt/Tgt	-8,24	0	0	possibly_damaging	0,71	neutral	0,18	neutral	1,42	deleterious	-4,1	neutral	-2,31	low_impact	1,7	neutral	0,79	neutral	0,42	deleterious	2,87	21,7	0,33	0,5	NA	NA	neutral	0,38	neutral	0,29	neutral	0,16	7	neutral	0,86	neutral	0,24	neutral	-3	deleterious	0,51	low_impact	-1,08	medium_impact	-0,17	medium_impact	0,56	0,2	0,8	26,14	26,33	N	0,36	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11015	11015	A	G	MI.16863	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	256	86	S	G	Agt/Ggt	-8,24	0	0	benign	0,04	neutral	0,36	neutral	1,45	neutral	-0,53	neutral	-1,5	low_impact	1,35	neutral	0,79	neutral	0,66	deleterious	0,29	5,58	0,44	0,55	NA	NA	neutral	0,22	neutral	0,26	neutral	0,16	7	neutral	0,61	deleterious	0,66	neutral	-6	neutral	0,09	medium_impact	0,58	medium_impact	0,06	medium_impact	0,21	0,38	0,8	26,14	26,33	N	0,43	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11016	11016	G	T	MI.16864	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	257	86	S	I	aGt/aTt	-0,4	0	0,06	benign	0,34	neutral	0,41	neutral	1,44	neutral	-2,38	neutral	-2,27	low_impact	1,35	neutral	0,8	neutral	0,67	neutral	1,06	11	0,26	0,45	NA	NA	neutral	0,44	neutral	0,3	neutral	0,22	6	neutral	0,51	deleterious	0,54	neutral	-6	neutral	0,2	medium_impact	-0,45	medium_impact	0,11	medium_impact	0,21	0,32	0,8	26,14	26,33	N	0,31	N	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11016	11016	G	A	MI.16865	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	257	86	S	N	aGt/aAt	-0,4	0	0,06	benign	0	neutral	0,35	neutral	1,57	neutral	-1,06	neutral	0,21	neutral_impact	-0,14	neutral	0,76	neutral	0,99	neutral	-0,63	0,11	0,65	0,7	NA	NA	neutral	0,16	neutral	0,16	neutral	0,21	6	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,08	high_impact	2,1	medium_impact	0,05	low_impact	-1,26	0,39	0,8	26,14	26,33	N	0,53	P	0,01	polymorphism	1	0	rs28594904	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	11016	11016	G	C	MI.16866	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	257	86	S	T	aGt/aCt	-0,4	0	0,06	benign	0,06	neutral	0,43	neutral	1,52	neutral	-0,99	neutral	-0,71	neutral_impact	0,46	neutral	0,76	neutral	0,81	neutral	-0,21	1,02	0,58	0,65	NA	NA	neutral	0,1	neutral	0,13	neutral	0,22	6	neutral	0,52	deleterious	0,69	neutral	-6	neutral	0,08	medium_impact	0,41	medium_impact	0,13	medium_impact	-0,67	0,49	0,8	26,14	26,33	N	0,49	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11018	11018	G	C	MI.16867	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	259	87	E	Q	Gaa/Caa	-2,94	0	0	benign	0,34	neutral	0,16	neutral	1,34	neutral	-1,95	neutral	-2	medium_impact	2,72	neutral	0,69	damaging	0,19	deleterious	3,25	22,8	0,74	0,8	NA	NA	disease	0,6	neutral	0,44	neutral	0,46	1	neutral	0,81	neutral	0,41	neutral	-3	deleterious	0,79	medium_impact	-0,45	medium_impact	-0,2	medium_impact	1,57	0,49	0,8	19,61	16,52	N	0,33	N	0,81	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11018	11018	G	A	MI.16868	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	259	87	E	K	Gaa/Aaa	-2,94	0	0	possibly_damaging	0,81	neutral	0,3	neutral	1,37	neutral	-1,13	deleterious	-2,69	medium_impact	2,37	neutral	0,71	damaging	0,15	deleterious	4,36	24,1	0,27	0,45	NA	NA	disease	0,7	disease	0,55	disease	0,52	0	neutral	0,85	neutral	0,25	NA	0	deleterious	0,82	low_impact	-1,31	medium_impact	0	medium_impact	1,22	0,42	0,8	19,61	16,52	N	0,39	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11019	11019	A	G	MI.16869	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	260	87	E	G	gAa/gGa	6,06	1	0	possibly_damaging	0,88	neutral	0,11	neutral	1,28	neutral	-2,62	deleterious	-4,59	medium_impact	2,92	neutral	0,77	neutral	0,57	deleterious	4,17	23,8	0,5	0,6	NA	NA	disease	0,65	disease	0,67	disease	0,68	4	neutral	0,96	neutral	0,12	NA	0	deleterious	0,8	low_impact	-1,53	medium_impact	-0,31	medium_impact	1,76	0,15	0,8	19,61	16,52	P	0,65	P	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8480	8480	C	G	MI.1687	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	115	39	P	A	Cca/Gca	-1,95	0	0	probably_damaging	0,99	neutral	0,59	neutral	1,62	neutral	0,71	deleterious	-3	medium_impact	2,15	neutral	0,99	neutral	0,83	neutral	1,61	13,91	0,46889253	0,85	neutral	0,26	neutral	0,08	neutral	0,34	neutral	0,05	9	deleterious	0,99	neutral	0,3	deleterious	1	deleterious	0,69	low_impact	-2,65	medium_impact	0,38	medium_impact	0,75	0,74	0,85	7,35	7,21	N	0,43	N	0,4	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11019	11019	A	C	MI.16870	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	260	87	E	A	gAa/gCa	6,06	1	0	possibly_damaging	0,81	neutral	0,19	neutral	1,33	neutral	-1,86	deleterious	-4,12	medium_impact	3,27	neutral	0,71	damaging	0,19	deleterious	3,59	23,2	0,53	0,6	NA	NA	disease	0,53	disease	0,66	disease	0,59	2	neutral	0,89	neutral	0,19	NA	0	deleterious	0,79	low_impact	-1,31	medium_impact	-0,15	high_impact	2,11	0,27	0,8	19,61	16,52	P	0,68	P	0,78	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11019	11019	A	T	MI.16871	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	260	87	E	V	gAa/gTa	6,06	1	0	probably_damaging	0,96	neutral	0,09	neutral	1,28	deleterious	-3,39	deleterious	-4,87	medium_impact	3,27	neutral	0,65	damaging	0,15	deleterious	4,12	23,8	0,27	0,45	NA	NA	disease	0,74	disease	0,67	disease	0,65	3	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,83	low_impact	-2,01	medium_impact	-0,36	high_impact	2,11	0,35	0,8	19,61	16,52	P	0,62	P	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11020	11020	A	C	MI.16872	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	261	87	E	D	gaA/gaC	5,6	1	0	possibly_damaging	0,73	neutral	0,21	neutral	1,33	neutral	-0,36	neutral	-1,72	medium_impact	2,58	neutral	0,76	neutral	0,59	deleterious	3,51	23,1	0,62	0,65	NA	NA	disease	0,58	neutral	0,38	neutral	0,44	1	neutral	0,84	neutral	0,24	NA	0	deleterious	0,78	low_impact	-1,12	medium_impact	-0,12	medium_impact	1,43	0,52	0,8	19,61	16,52	P	0,67	P	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11020	11020	A	T	MI.16873	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	261	87	E	D	gaA/gaT	5,6	1	0	possibly_damaging	0,73	neutral	0,21	neutral	1,33	neutral	-0,36	neutral	-1,72	medium_impact	2,58	neutral	0,76	neutral	0,59	deleterious	3,62	23,2	0,62	0,65	NA	NA	disease	0,58	neutral	0,38	neutral	0,44	1	neutral	0,84	neutral	0,24	NA	0	deleterious	0,78	low_impact	-1,12	medium_impact	-0,12	medium_impact	1,43	0,52	0,8	19,61	16,52	P	0,68	P	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11021	11021	C	T	MI.16874	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	262	88	P	S	Cca/Tca	-0,17	0	0	benign	0,02	neutral	0,35	neutral	1,41	neutral	-0,88	neutral	-1,61	low_impact	1,29	neutral	0,81	neutral	0,96	deleterious	0,36	6,25	0,42	0,55	NA	NA	neutral	0,37	neutral	0,36	neutral	0,16	7	neutral	0,64	deleterious	0,67	neutral	-6	neutral	0,15	medium_impact	0,87	medium_impact	0,05	medium_impact	0,15	0,2	0,8	8,93	15,25	N	0,38	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11021	11021	C	G	MI.16875	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	262	88	P	A	Cca/Gca	-0,17	0	0	benign	0,17	neutral	0,3	neutral	1,29	neutral	-1,96	deleterious	-2,61	medium_impact	2,69	neutral	0,69	neutral	0,58	neutral	1,1	11,22	0,65	0,7	NA	NA	neutral	0,31	disease	0,58	neutral	0,38	2	neutral	0,65	deleterious	0,57	neutral	-3	neutral	0,3	medium_impact	-0,07	medium_impact	0	medium_impact	1,54	0,38	0,8	8,93	15,25	N	0,43	N	0,49	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11021	11021	C	A	MI.16876	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	262	88	P	T	Cca/Aca	-0,17	0	0	benign	0,25	neutral	0,32	neutral	1,29	neutral	-1,9	neutral	-2,1	low_impact	1,47	neutral	0,8	neutral	0,96	deleterious	0,75	9,15	0,46	0,55	NA	NA	neutral	0,33	neutral	0,36	neutral	0,16	7	neutral	0,61	deleterious	0,54	neutral	-6	neutral	0,39	medium_impact	-0,27	medium_impact	0,02	medium_impact	0,33	0,38	0,8	8,93	15,25	N	0,38	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11022	11022	C	T	MI.16877	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	263	88	P	L	cCa/cTa	-0,86	0	0	possibly_damaging	0,57	neutral	0,51	neutral	1,21	deleterious	-3,47	deleterious	-4,19	medium_impact	2,49	neutral	0,7	neutral	0,46	deleterious	3,76	23,3	0,49	0,55	NA	NA	disease	0,57	disease	0,56	disease	0,63	3	neutral	0,55	deleterious	0,47	NA	0	deleterious	0,52	medium_impact	-0,83	medium_impact	0,21	medium_impact	1,34	0,7	0,85	8,93	15,25	N	0,31	N	0,75	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11022	11022	C	A	MI.16878	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	263	88	P	Q	cCa/cAa	-0,86	0	0	possibly_damaging	0,75	neutral	0,17	neutral	1,22	deleterious	-3,22	deleterious	-2,61	medium_impact	3,04	neutral	0,77	neutral	0,56	deleterious	3,7	23,3	0,38	0,5	NA	NA	disease	0,61	disease	0,54	disease	0,61	2	neutral	0,88	neutral	0,21	NA	0	deleterious	0,62	low_impact	-1,17	medium_impact	-0,18	medium_impact	1,88	0,24	0,8	8,93	15,25	N	0,39	N	0,58	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11022	11022	C	G	MI.16879	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	263	88	P	R	cCa/cGa	-0,86	0	0	possibly_damaging	0,57	neutral	0,2	neutral	1,22	deleterious	-3,34	deleterious	-3,26	medium_impact	3,04	neutral	0,63	neutral	0,39	deleterious	3,1	22,5	0,33	0,5	NA	NA	disease	0,56	disease	0,65	disease	0,65	3	neutral	0,8	neutral	0,32	NA	0	deleterious	0,61	medium_impact	-0,83	medium_impact	-0,14	medium_impact	1,88	0,36	0,8	8,93	15,25	N	0,37	N	0,73	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8481	8481	C	T	MI.1688	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	116	39	P	L	cCa/cTa	-2,65	0	0	probably_damaging	1	neutral	0,7	neutral	1,56	neutral	-0,73	deleterious	-3,92	low_impact	1,46	neutral	0,98	neutral	0,92	deleterious	2,92	22	0,43790363	0,85	neutral	0,28	neutral	0,18	neutral	0,33	neutral	0,13	8	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,5	medium_impact	0,15	0,84	0,85	7,35	7,21	N	0,37	N	0,29	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	C8481T	Tetralogy of Fallot patient	+	-	Reported	1
chrM	11024	11024	C	A	MI.16880	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	265	89	L	M	Cta/Ata	-9,85	0	0	probably_damaging	0,94	neutral	0,26	neutral	1,5	neutral	-1,43	neutral	-0,4	medium_impact	2,44	neutral	0,77	neutral	0,91	deleterious	1,97	16,02	0,25	0,45	NA	NA	neutral	0,09	neutral	0,17	neutral	0,24	5	neutral	0,96	neutral	0,16	deleterious	1	deleterious	0,53	low_impact	-1,84	medium_impact	-0,05	medium_impact	1,29	0,36	0,8	29,63	19,55	P	0,55	P	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11024	11024	C	G	MI.16881	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	265	89	L	V	Cta/Gta	-9,85	0	0	possibly_damaging	0,68	neutral	0,53	neutral	1,51	neutral	-1,25	neutral	-0,53	low_impact	1,28	neutral	0,76	neutral	0,92	neutral	-0,13	1,55	0,25	0,45	NA	NA	neutral	0,13	neutral	0,29	neutral	0,25	5	neutral	0,65	neutral	0,43	neutral	-3	neutral	0,18	low_impact	-1,03	medium_impact	0,23	medium_impact	0,14	0,41	0,8	29,63	19,55	N	0,34	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11025	11025	T	A	MI.16882	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	266	89	L	Q	cTa/cAa	-5,47	0	0,01	probably_damaging	0,92	neutral	0,3	neutral	1,54	neutral	-0,71	neutral	-1,83	medium_impact	2,08	neutral	0,78	neutral	0,78	deleterious	2,43	19,05	0,21	0,45	NA	NA	neutral	0,32	neutral	0,23	neutral	0,19	6	neutral	0,93	neutral	0,19	deleterious	1	deleterious	0,49	low_impact	-1,71	medium_impact	0	medium_impact	0,93	0,2	0,8	29,63	19,55	N	0,42	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11025	11025	T	C	MI.16883	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	266	89	L	P	cTa/cCa	-5,47	0	0,01	benign	0,02	neutral	0,24	neutral	1,5	neutral	-1,56	neutral	-2,17	neutral_impact	0,48	neutral	0,8	neutral	0,99	deleterious	0,31	5,77	0,15	0,45	NA	NA	neutral	0,41	neutral	0,24	neutral	0,18	6	neutral	0,75	deleterious	0,61	neutral	-6	neutral	0,15	medium_impact	0,87	medium_impact	-0,08	medium_impact	-0,65	0,22	0,8	29,63	19,55	N	0,39	N	0,03	polymorphism	1	0,02	rs201300253	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11025	11025	T	G	MI.16884	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	266	89	L	R	cTa/cGa	-5,47	0	0,01	probably_damaging	0,92	neutral	0,34	neutral	1,53	neutral	-0,84	neutral	-2,18	medium_impact	2,44	neutral	0,7	neutral	0,58	deleterious	2,32	18,29	0,17	0,45	NA	NA	neutral	0,43	neutral	0,4	neutral	0,22	6	neutral	0,93	neutral	0,21	deleterious	1	deleterious	0,52	low_impact	-1,71	medium_impact	0,04	medium_impact	1,29	0,16	0,8	29,63	19,55	N	0,39	N	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11027	11027	T	C	MI.16885	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	268	90	S	P	Tca/Cca	-9,39	0	0	benign	0,02	neutral	0,23	neutral	1,53	neutral	-1,98	neutral	-1,61	neutral_impact	0,45	neutral	0,77	neutral	0,93	deleterious	0,85	9,75	0,28	0,45	NA	NA	disease	0,57	neutral	0,2	neutral	0,43	1	neutral	0,76	deleterious	0,61	neutral	-6	deleterious	0,46	medium_impact	0,87	medium_impact	-0,09	medium_impact	-0,68	0,23	0,8	29,41	24,09	N	0,42	N	0,68	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11027	11027	T	G	MI.16886	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	268	90	S	A	Tca/Gca	-9,39	0	0	benign	0,25	neutral	0,36	neutral	1,56	neutral	-0,52	neutral	-0,82	low_impact	0,96	neutral	0,76	neutral	0,98	deleterious	0,05	3,07	0,49	0,55	NA	NA	neutral	0,15	neutral	0,28	neutral	0,18	7	neutral	0,56	deleterious	0,56	neutral	-6	neutral	0,1	medium_impact	-0,27	medium_impact	0,06	medium_impact	-0,18	0,31	0,8	29,41	24,09	N	0,45	N	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11027	11027	T	A	MI.16887	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	268	90	S	T	Tca/Aca	-9,39	0	0	benign	0,03	neutral	0,45	neutral	1,57	neutral	-1,05	neutral	0,38	neutral_impact	-0,06	neutral	0,76	neutral	0,99	neutral	-0,47	0,26	0,52	0,6	NA	NA	neutral	0,08	neutral	0,17	neutral	0,19	6	neutral	0,52	deleterious	0,71	neutral	-6	neutral	0,1	medium_impact	0,7	medium_impact	0,15	low_impact	-1,19	0,46	0,8	29,41	24,09	N	0,48	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11028	11028	C	G	MI.16888	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	269	90	S	W	tCa/tGa	-5,7	0	0	probably_damaging	0,92	deleterious	0,03	neutral	1,48	deleterious	-4,25	neutral	-2,37	medium_impact	2	neutral	0,78	neutral	0,43	deleterious	2,86	21,7	0,17	0,45	NA	NA	disease	0,61	neutral	0,46	neutral	0,48	0	deleterious	0,99	neutral	0,06	deleterious	5	deleterious	0,65	low_impact	-1,71	medium_impact	-0,64	medium_impact	0,85	0,17	0,8	29,41	24,09	N	0,35	N	0,58	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11028	11028	C	T	MI.16889	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	269	90	S	L	tCa/tTa	-5,7	0	0	benign	0,02	neutral	0,19	neutral	1,56	neutral	-2,04	neutral	-1,24	neutral_impact	0,41	neutral	0,81	neutral	0,95	deleterious	0,87	9,9	0,34	0,5	NA	NA	neutral	0,35	neutral	0,3	neutral	0,18	6	neutral	0,8	deleterious	0,59	neutral	-6	neutral	0,1	medium_impact	0,87	medium_impact	-0,15	medium_impact	-0,72	0,59	0,8	29,41	24,09	N	0,42	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8481	8481	C	A	MI.1689	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	116	39	P	Q	cCa/cAa	-2,65	0	0	probably_damaging	1	neutral	0,36	neutral	1,59	neutral	0,24	deleterious	-2,64	low_impact	1,52	neutral	0,99	neutral	0,81	deleterious	2,11	16,91	0,42878708	0,85	neutral	0,42	neutral	0,13	neutral	0,25	neutral	0,07	9	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,15	medium_impact	0,21	0,59	0,85	7,35	7,21	N	0,5	N	0,57	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11030	11030	C	T	MI.16890	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	271	91	R	W	Cga/Tga	-3,86	0	0	benign	0,11	neutral	0,13	neutral	1,39	deleterious	-6,89	deleterious	-5,05	medium_impact	2,74	neutral	0,7	neutral	0,3	deleterious	5,09	25,3	0,2	0,45	NA	NA	disease	0,85	disease	0,67	disease	0,75	5	neutral	0,85	deleterious	0,51	neutral	-3	deleterious	0,85	medium_impact	0,14	medium_impact	-0,26	medium_impact	1,59	0,87	0,9	24,84	23,34	N	0,32	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11030	11030	C	G	MI.16891	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	271	91	R	G	Cga/Gga	-3,86	0	0	possibly_damaging	0,78	neutral	0,24	neutral	1,42	deleterious	-3,33	deleterious	-4,42	medium_impact	3,08	neutral	0,72	neutral	0,41	deleterious	4,12	23,8	0,24	0,45	NA	NA	disease	0,72	disease	0,71	disease	0,7	4	neutral	0,85	neutral	0,23	NA	0	deleterious	0,82	low_impact	-1,23	medium_impact	-0,08	medium_impact	1,92	0,23	0,8	24,84	23,34	N	0,34	N	0,81	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11031	11031	G	T	MI.16892	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	272	91	R	L	cGa/cTa	1,21	0,02	0	possibly_damaging	0,64	neutral	0,54	neutral	1,43	deleterious	-3,1	deleterious	-4,53	medium_impact	2,19	neutral	0,78	neutral	0,55	deleterious	4,16	23,8	0,24	0,45	NA	NA	disease	0,86	disease	0,68	disease	0,7	4	neutral	0,61	neutral	0,45	NA	0	deleterious	0,85	medium_impact	-0,95	medium_impact	0,24	medium_impact	1,04	0,06	0,8	24,84	23,34	N	0,24	N	0,61	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11031	11031	G	A	MI.16893	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	272	91	R	Q	cGa/cAa	1,21	0,02	0	benign	0,09	neutral	0,22	neutral	1,48	neutral	-1,98	neutral	-2,15	low_impact	1,56	neutral	0,75	neutral	0,63	deleterious	4,34	24	0,26	0,45	NA	NA	disease	0,69	disease	0,54	neutral	0,49	0	neutral	0,75	deleterious	0,57	neutral	-6	deleterious	0,8	medium_impact	0,23	medium_impact	-0,11	medium_impact	0,42	0,77	0,85	24,84	23,34	N	0,41	N	0,3	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11031	11031	G	C	MI.16894	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	272	91	R	P	cGa/cCa	1,21	0,02	0	probably_damaging	0,95	neutral	0,12	neutral	1,4	deleterious	-4,07	deleterious	-4,44	medium_impact	3,08	neutral	0,65	damaging	0,28	deleterious	4,13	23,8	0,13	0,4	NA	NA	disease	0,86	disease	0,71	disease	0,78	6	neutral	0,98	neutral	0,09	deleterious	1	deleterious	0,88	low_impact	-1,92	medium_impact	-0,28	medium_impact	1,92	0,19	0,8	24,84	23,34	N	0,36	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11033	11033	A	C	MI.16895	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	274	92	K	Q	Aaa/Caa	-0,4	0	0	probably_damaging	1	neutral	1	neutral	1,61	neutral	0,16	neutral	-1,08	low_impact	1,12	neutral	0,68	neutral	0,82	deleterious	0,64	8,45	0,35	0,5	NA	NA	neutral	0,13	neutral	0,24	neutral	0,21	6	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,71	low_impact	-3,54	high_impact	1,88	medium_impact	-0,02	0,34	0,8	14,6	18,78	N	0,32	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11033	11033	A	G	MI.16896	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	274	92	K	E	Aaa/Gaa	-0,4	0	0	probably_damaging	1	neutral	0,3	neutral	1,5	neutral	-0,71	neutral	-1,82	medium_impact	3,17	neutral	0,67	damaging	0,18	deleterious	3,92	23,5	0,25	0,45	NA	NA	disease	0,7	disease	0,67	disease	0,58	2	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	0	high_impact	2,01	0,41	0,8	14,6	18,78	N	0,41	N	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11034	11034	A	T	MI.16897	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	275	92	K	M	aAa/aTa	2,14	0,93	0	probably_damaging	1	neutral	0,1	neutral	1,38	deleterious	-3,54	deleterious	-3,24	medium_impact	2,83	neutral	0,73	damaging	0,2	deleterious	3,57	23,1	0,19	0,45	NA	NA	disease	0,57	disease	0,63	disease	0,64	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,33	medium_impact	1,67	0,19	0,8	14,6	18,78	N	0,4	N	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11034	11034	A	C	MI.16898	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	275	92	K	T	aAa/aCa	2,14	0,93	0	probably_damaging	1	neutral	0,23	neutral	1,44	neutral	-1,62	deleterious	-3,48	medium_impact	2,83	neutral	0,7	damaging	0,24	deleterious	3,27	22,8	0,25	0,45	NA	NA	neutral	0,5	disease	0,56	disease	0,59	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,09	medium_impact	1,67	0,39	0,8	14,6	18,78	N	0,46	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11035	11035	A	T	MI.16899	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	276	92	K	N	aaA/aaT	8,59	1	0	probably_damaging	1	neutral	0,33	neutral	1,44	neutral	-1,51	deleterious	-2,79	medium_impact	3,17	neutral	0,68	damaging	0,19	deleterious	3,61	23,2	0,53	0,6	NA	NA	disease	0,57	disease	0,64	disease	0,54	1	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,03	high_impact	2,01	0,38	0,8	14,6	18,78	P	0,66	P	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8605	8605	C	T	MI.169	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	79	27	P	S	Ccc/Tcc	-6,58	0	0	probably_damaging	1	neutral	0,45	neutral	4,42	neutral	0,41	deleterious	-7,11	medium_impact	2,41	neutral	0,67	neutral	0,62	deleterious	3,67	23,2	0,46	0,65	neutral	0,35	disease	0,75	neutral	0,45	disease	0,54	1	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,24	medium_impact	0,97	0,26	0,9	48,23	8,81	N	0,32	N	0,84	polymorphism	0,75	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8481	8481	C	G	MI.1690	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	116	39	P	R	cCa/cGa	-2,65	0	0	probably_damaging	1	neutral	0,4	neutral	1,65	neutral	1,18	deleterious	-3,75	medium_impact	3,13	neutral	1	neutral	0,37	deleterious	2,13	17,07	0,40896277	0,85	neutral	0,43	neutral	0,22	neutral	0,43	neutral	0,13	7	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,19	medium_impact	1,59	0,68	0,85	7,35	7,21	N	0,48	N	0,58	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11035	11035	A	C	MI.16900	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	276	92	K	N	aaA/aaC	8,59	1	0	probably_damaging	1	neutral	0,33	neutral	1,44	neutral	-1,51	deleterious	-2,79	medium_impact	3,17	neutral	0,68	damaging	0,19	deleterious	3,53	23,1	0,53	0,6	NA	NA	disease	0,57	disease	0,64	disease	0,54	1	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,03	high_impact	2,01	0,38	0,8	14,6	18,78	P	0,66	P	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11036	11036	A	C	MI.16901	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	277	93	K	Q	Aaa/Caa	2,6	1	0	probably_damaging	1	neutral	0,08	neutral	1,5	neutral	-0,84	neutral	-2,29	medium_impact	2,52	neutral	0,61	neutral	0,38	deleterious	3	22,2	0,27	0,45	NA	NA	neutral	0,4	neutral	0,35	neutral	0,15	7	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,39	medium_impact	1,37	0,34	0,8	46,84	8,88	P	0,62	P	0,86	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11036	11036	A	G	MI.16902	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	277	93	K	E	Aaa/Gaa	2,6	1	0	probably_damaging	1	neutral	0,05	neutral	1,52	neutral	-0,66	deleterious	-2,56	medium_impact	2,73	damaging	0,48	damaging	0,14	deleterious	3,58	23,2	0,18	0,45	NA	NA	disease	0,68	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,58	0,36	0,8	46,84	8,88	P	0,62	P	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11037	11037	A	C	MI.16903	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	278	93	K	T	aAa/aCa	3,75	1	0	probably_damaging	1	neutral	0,14	neutral	1,48	neutral	-1,2	deleterious	-3,85	medium_impact	3,08	damaging	0,49	damaging	0,14	deleterious	3,41	23	0,15	0,45	NA	NA	neutral	0,37	disease	0,62	neutral	0,37	3	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	-0,24	medium_impact	1,92	0,2	0,8	46,84	8,88	P	0,67	P	0,77	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11037	11037	A	T	MI.16904	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	278	93	K	M	aAa/aTa	3,75	1	0	probably_damaging	1	neutral	0,07	neutral	1,42	deleterious	-3,12	deleterious	-3,85	medium_impact	3,08	damaging	0,48	damaging	0,13	deleterious	3,63	23,2	0,13	0,4	NA	NA	disease	0,52	disease	0,61	disease	0,7	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,43	medium_impact	1,92	0,21	0,8	46,84	8,88	P	0,62	P	0,42	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11038	11038	A	T	MI.16905	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	279	93	K	N	aaA/aaT	3,29	1	0	probably_damaging	1	neutral	0,31	neutral	1,51	neutral	-0,79	deleterious	-3,08	medium_impact	2,27	damaging	0,52	damaging	0,13	deleterious	3,72	23,3	0,5	0,6	NA	NA	neutral	0,45	disease	0,53	neutral	0,34	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	0,01	medium_impact	1,12	0,3	0,8	46,84	8,88	P	0,58	P	0,72	polymorphism	1	0,07	rs386829117	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11038	11038	A	C	MI.16906	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	279	93	K	N	aaA/aaC	3,29	1	0	probably_damaging	1	neutral	0,31	neutral	1,51	neutral	-0,79	deleterious	-3,08	medium_impact	2,27	damaging	0,52	damaging	0,13	deleterious	3,67	23,3	0,5	0,6	NA	NA	neutral	0,45	disease	0,53	neutral	0,34	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	0,01	medium_impact	1,12	0,3	0,8	46,84	8,88	P	0,58	P	0,72	polymorphism	1	0,07	rs386829117	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11039	11039	C	G	MI.16907	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	280	94	L	V	Ctc/Gtc	0,06	0	0	possibly_damaging	0,52	neutral	0,39	neutral	1,48	neutral	-0,87	neutral	-0,79	medium_impact	2,12	neutral	0,74	neutral	0,82	deleterious	2,06	16,63	0,45	0,55	NA	NA	neutral	0,17	neutral	0,24	neutral	0,22	6	neutral	0,6	neutral	0,44	NA	0	deleterious	0,7	medium_impact	-0,75	medium_impact	0,09	medium_impact	0,97	0,37	0,8	26,36	16,11	N	0,5	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11039	11039	C	A	MI.16908	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	280	94	L	I	Ctc/Atc	0,06	0	0	benign	0,12	neutral	0,48	neutral	1,48	neutral	-0,79	neutral	-0,56	low_impact	1,48	neutral	0,68	neutral	0,85	deleterious	2,77	21,2	0,39	0,5	NA	NA	neutral	0,11	neutral	0,2	neutral	0,23	5	neutral	0,44	deleterious	0,68	neutral	-6	deleterious	0,69	medium_impact	0,1	medium_impact	0,18	medium_impact	0,34	0,48	0,8	26,36	16,11	N	0,49	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11039	11039	C	T	MI.16909	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	280	94	L	F	Ctc/Ttc	0,06	0	0	benign	0,17	neutral	0,77	neutral	1,42	neutral	-1,57	neutral	-1,52	medium_impact	2,37	neutral	0,79	neutral	0,69	deleterious	2,7	20,8	0,28	0,45	NA	NA	neutral	0,2	neutral	0,24	neutral	0,19	6	neutral	0,12	deleterious	0,8	neutral	-3	deleterious	0,7	medium_impact	-0,07	medium_impact	0,5	medium_impact	1,22	0,48	0,8	26,36	16,11	N	0,3	N	0,99	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8483	8483	A	C	MI.1691	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	118	40	K	Q	Aag/Cag	-2,65	0	0	benign	0,37	neutral	0,66	neutral	1,81	neutral	-2,26	deleterious	-3,02	medium_impact	2,6	neutral	0,98	neutral	0,52	neutral	1,68	14,28	0,8102732	0,9	neutral	0,39	neutral	0,48	neutral	0,4	neutral	0,35	3	neutral	0,3	deleterious	0,65	neutral	-3	neutral	0,32	medium_impact	-0,54	medium_impact	0,45	medium_impact	1,13	0,51	0,85	NA	NA	N	0,32	N	0,59	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11040	11040	T	A	MI.16910	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	281	94	L	H	cTc/cAc	-0,4	0	0	probably_damaging	0,98	neutral	0,35	neutral	1,36	deleterious	-3,56	deleterious	-2,97	medium_impact	2,92	neutral	0,77	neutral	0,74	deleterious	3,13	22,6	0,08	0,35	NA	NA	neutral	0,42	disease	0,52	neutral	0,35	3	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,75	low_impact	-2,31	medium_impact	0,05	medium_impact	1,76	0,15	0,8	26,36	16,11	N	0,39	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11040	11040	T	G	MI.16911	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	281	94	L	R	cTc/cGc	-0,4	0	0	probably_damaging	0,96	neutral	0,24	neutral	1,37	deleterious	-3,12	deleterious	-2,62	medium_impact	2,92	neutral	0,7	neutral	0,43	deleterious	4,05	23,7	0,07	0,35	NA	NA	disease	0,58	disease	0,59	disease	0,7	4	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,79	low_impact	-2,01	medium_impact	-0,08	medium_impact	1,76	0,11	0,8	26,36	16,11	N	0,38	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11040	11040	T	C	MI.16912	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	281	94	L	P	cTc/cCc	-0,4	0	0	probably_damaging	0,97	neutral	0,12	neutral	1,36	deleterious	-3,62	deleterious	-3,1	medium_impact	2,92	neutral	0,62	neutral	0,37	deleterious	3,83	23,4	0,02	0,35	NA	NA	disease	0,69	disease	0,63	disease	0,72	4	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,82	low_impact	-2,14	medium_impact	-0,28	medium_impact	1,76	0,06	0,8	26,36	16,11	N	0,35	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11042	11042	T	G	MI.16913	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	283	95	Y	D	Tac/Gac	-11,24	0	0	probably_damaging	0,98	deleterious	0	neutral	1,24	deleterious	-6,49	deleterious	-7,21	medium_impact	3,34	neutral	0,71	neutral	0,38	deleterious	3,79	23,4	0,02	0,35	NA	NA	disease	0,86	disease	0,76	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,86	low_impact	-2,31	low_impact	-1,48	high_impact	2,18	0,12	0,8	45,75	11,64	N	0,39	N	0,93	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11042	11042	T	A	MI.16914	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	283	95	Y	N	Tac/Aac	-11,24	0	0	probably_damaging	0,98	deleterious	0,04	neutral	1,24	deleterious	-5,33	deleterious	-6,57	medium_impact	3,34	neutral	0,72	neutral	0,54	deleterious	3,87	23,5	0,03	0,35	NA	NA	disease	0,78	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,82	low_impact	-2,31	medium_impact	-0,57	high_impact	2,18	0,22	0,8	45,75	11,64	N	0,42	N	0,89	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11042	11042	T	C	MI.16915	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	283	95	Y	H	Tac/Cac	-11,24	0	0	probably_damaging	0,98	deleterious	0	neutral	1,26	deleterious	-4,1	deleterious	-3,73	medium_impact	3,34	neutral	0,73	neutral	0,41	deleterious	3,42	23	0,08	0,35	NA	NA	disease	0,72	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-2,31	low_impact	-1,48	high_impact	2,18	0,22	0,8	45,75	11,64	N	0,38	N	0,84	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11043	11043	A	T	MI.16916	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	284	95	Y	F	tAc/tTc	2,83	0,23	0	benign	0,17	neutral	1	neutral	2,58	neutral	2,49	neutral	-2,23	low_impact	1,49	neutral	0,79	neutral	0,98	deleterious	2,6	20,2	0,16	0,45	NA	NA	neutral	0,14	neutral	0,32	neutral	0,18	6	neutral	0,17	deleterious	0,92	neutral	-6	deleterious	0,74	medium_impact	-0,07	high_impact	1,88	medium_impact	0,35	0,51	0,8	45,75	11,64	N	0,36	N	0,18	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11043	11043	A	G	MI.16917	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	284	95	Y	C	tAc/tGc	2,83	0,23	0	probably_damaging	0,99	neutral	0,05	neutral	1,24	deleterious	-6,5	deleterious	-6,41	medium_impact	3	neutral	0,75	neutral	0,39	deleterious	3,93	23,5	0,03	0,35	NA	NA	disease	0,79	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,82	low_impact	-2,59	medium_impact	-0,52	medium_impact	1,84	0,15	0,8	45,75	11,64	N	0,41	N	0,94	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11043	11043	A	C	MI.16918	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	284	95	Y	S	tAc/tCc	2,83	0,23	0	probably_damaging	0,98	neutral	0,05	neutral	1,25	deleterious	-5,05	deleterious	-6,44	medium_impact	3,34	neutral	0,72	neutral	0,54	deleterious	4,06	23,7	0,03	0,35	NA	NA	disease	0,77	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,83	low_impact	-2,31	medium_impact	-0,52	high_impact	2,18	0,23	0,8	45,75	11,64	N	0,43	N	0,9	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11045	11045	C	A	MI.16919	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	286	96	L	I	Ctc/Atc	-4,55	0	0	benign	0,08	neutral	1	neutral	1,57	neutral	-1,26	neutral	1,02	neutral_impact	-0,6	neutral	0,71	neutral	0,97	neutral	1,37	12,62	0,29	0,45	NA	NA	neutral	0,04	neutral	0,14	neutral	0,2	6	neutral	0,08	deleterious	0,96	neutral	-6	deleterious	0,69	medium_impact	0,28	high_impact	1,88	low_impact	-1,72	0,5	0,8	25,27	24,78	N	0,41	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8483	8483	A	G	MI.1692	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	118	40	K	E	Aag/Gag	-2,65	0	0	benign	0,17	neutral	0,47	neutral	1,84	neutral	-1,53	deleterious	-2,81	medium_impact	2,65	neutral	1	neutral	0,85	deleterious	2,17	17,28	0,53197893	0,85	neutral	0,35	neutral	0,42	neutral	0,47	neutral	0,21	6	neutral	0,44	deleterious	0,65	neutral	-3	neutral	0,34	medium_impact	-0,1	medium_impact	0,26	medium_impact	1,17	0,5	0,85	NA	NA	N	0,45	N	0,35	polymorphism	1	0,14	rs377093295	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11045	11045	C	G	MI.16920	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	286	96	L	V	Ctc/Gtc	-4,55	0	0	benign	0,05	neutral	0,15	neutral	1,39	neutral	-1,14	neutral	0,28	low_impact	1,32	neutral	0,76	neutral	0,89	deleterious	3,24	22,8	0,27	0,45	NA	NA	neutral	0,41	neutral	0,43	neutral	0,19	6	neutral	0,84	deleterious	0,55	neutral	-6	deleterious	0,74	medium_impact	0,48	medium_impact	-0,22	medium_impact	0,18	0,67	0,85	25,27	24,78	N	0,45	N	0,39	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11045	11045	C	T	MI.16921	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	286	96	L	F	Ctc/Ttc	-4,55	0	0	possibly_damaging	0,88	deleterious	0,03	neutral	1,3	neutral	-0,16	neutral	-1,78	medium_impact	2,48	neutral	0,65	neutral	0,72	deleterious	3,8	23,4	0,26	0,45	NA	NA	disease	0,51	neutral	0,44	neutral	0,48	0	deleterious	0,99	neutral	0,08	deleterious	4	deleterious	0,76	low_impact	-1,53	medium_impact	-0,64	medium_impact	1,33	0,51	0,8	25,27	24,78	N	0,46	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11046	11046	T	A	MI.16922	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	287	96	L	H	cTc/cAc	0,75	0,37	0	probably_damaging	0,98	deleterious	0,01	neutral	1,26	neutral	-2,92	deleterious	-4,07	medium_impact	2,48	neutral	0,66	neutral	0,59	deleterious	4	23,6	0,05	0,35	NA	NA	disease	0,65	disease	0,66	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-2,31	medium_impact	-0,92	medium_impact	1,33	0,2	0,8	25,27	24,78	N	0,33	N	0,88	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11046	11046	T	C	MI.16923	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	287	96	L	P	cTc/cCc	0,75	0,37	0	probably_damaging	0,96	deleterious	0,01	neutral	1,26	deleterious	-3,39	deleterious	-4,07	medium_impact	2,48	damaging	0,58	neutral	0,45	deleterious	3,77	23,4	0,02	0,35	NA	NA	disease	0,85	disease	0,71	disease	0,8	6	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,87	low_impact	-2,01	medium_impact	-0,92	medium_impact	1,33	0,38	0,8	25,27	24,78	N	0,31	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11046	11046	T	G	MI.16924	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	287	96	L	R	cTc/cGc	0,75	0,37	0	probably_damaging	0,93	deleterious	0,01	neutral	1,27	deleterious	-4,11	deleterious	-3,94	medium_impact	2,48	neutral	0,65	neutral	0,52	deleterious	4,1	23,7	0,02	0,35	NA	NA	disease	0,82	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,86	low_impact	-1,77	medium_impact	-0,92	medium_impact	1,33	0,11	0,8	25,27	24,78	N	0,32	N	0,96	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11048	11048	T	A	MI.16925	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	289	97	S	T	Tct/Act	-8,7	0	0	benign	0,03	neutral	0,68	neutral	1,62	neutral	0,41	neutral	0,18	neutral_impact	0	neutral	0,74	neutral	0,99	neutral	-0,96	0,02	0,25	0,45	NA	NA	neutral	0,06	neutral	0,17	neutral	0,19	6	neutral	0,27	deleterious	0,83	neutral	-6	neutral	0,11	medium_impact	0,7	medium_impact	0,39	low_impact	-1,13	0,67	0,85	18,74	14,9	N	0,48	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11048	11048	T	G	MI.16926	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	289	97	S	A	Tct/Gct	-8,7	0	0	benign	0,4	neutral	0,44	neutral	1,58	neutral	-0,12	neutral	-1,4	low_impact	1,66	neutral	0,77	neutral	0,86	deleterious	0,69	8,75	0,26	0,45	NA	NA	neutral	0,19	neutral	0,23	neutral	0,21	6	neutral	0,5	deleterious	0,52	neutral	-6	neutral	0,18	medium_impact	-0,55	medium_impact	0,14	medium_impact	0,52	0,6	0,8	18,74	14,9	N	0,4	N	0,27	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11048	11048	T	C	MI.16927	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	289	97	S	P	Tct/Cct	-8,7	0	0	possibly_damaging	0,89	neutral	0,13	neutral	1,48	neutral	-2,86	deleterious	-2,61	medium_impact	2,7	damaging	0,55	neutral	0,35	deleterious	3,44	23	0,05	0,35	NA	NA	disease	0,78	disease	0,54	disease	0,75	5	neutral	0,95	neutral	0,12	NA	0	deleterious	0,54	low_impact	-1,57	medium_impact	-0,26	medium_impact	1,55	0,33	0,8	18,74	14,9	N	0,39	N	0,74	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11049	11049	C	A	MI.16928	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	290	97	S	Y	tCt/tAt	-2,71	0	0	possibly_damaging	0,81	neutral	0,64	neutral	1,52	neutral	-1,15	deleterious	-3,15	medium_impact	2,7	neutral	0,8	neutral	0,51	deleterious	3,72	23,3	0,04	0,35	NA	NA	disease	0,56	neutral	0,45	disease	0,51	0	neutral	0,77	neutral	0,42	NA	0	deleterious	0,63	low_impact	-1,31	medium_impact	0,34	medium_impact	1,55	0,3	0,8	18,74	14,9	N	0,23	N	0,65	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11049	11049	C	T	MI.16929	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	290	97	S	F	tCt/tTt	-2,71	0	0	benign	0,07	neutral	1	neutral	1,65	neutral	0,63	deleterious	-3,07	low_impact	1,46	neutral	0,78	neutral	0,78	deleterious	3,85	23,4	0,06	0,35	NA	NA	neutral	0,46	neutral	0,32	neutral	0,23	5	neutral	0,07	deleterious	0,97	neutral	-6	deleterious	0,62	medium_impact	0,34	high_impact	1,88	medium_impact	0,32	0,29	0,8	18,74	14,9	N	0,21	N	0,11	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8484	8484	A	T	MI.1693	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	119	40	K	M	aAg/aTg	1,52	0	0	benign	0,04	neutral	0,28	neutral	1,78	deleterious	-3,59	deleterious	-4,28	medium_impact	2,86	neutral	0,99	neutral	0,78	deleterious	1,91	15,63	0,32447288	0,85	disease	0,64	neutral	0,36	neutral	0,43	neutral	0,27	5	neutral	0,7	deleterious	0,62	neutral	-3	neutral	0,24	medium_impact	0,55	medium_impact	0,06	medium_impact	1,35	0,38	0,85	NA	NA	N	0,53	P	0,33	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11049	11049	C	G	MI.16930	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	290	97	S	C	tCt/tGt	-2,71	0	0	probably_damaging	0,94	neutral	0,13	neutral	1,48	neutral	-2,69	neutral	-2,47	medium_impact	2,7	neutral	0,72	neutral	0,54	deleterious	3,33	22,9	0,06	0,35	NA	NA	neutral	0,49	neutral	0,31	neutral	0,47	1	neutral	0,97	neutral	0,1	deleterious	1	deleterious	0,66	low_impact	-1,84	medium_impact	-0,26	medium_impact	1,55	0,37	0,8	18,74	14,9	N	0,45	N	0,64	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11051	11051	A	C	MI.16931	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	292	98	M	L	Ata/Cta	-10,55	0	0	benign	0,33	neutral	1	neutral	1,74	neutral	2,5	neutral	-0,57	low_impact	1,16	neutral	0,68	neutral	0,95	deleterious	0,43	6,88	0,17	0,45	NA	NA	neutral	0,22	neutral	0,29	neutral	0,16	7	neutral	0,33	deleterious	0,84	neutral	-6	deleterious	0,52	medium_impact	-0,43	high_impact	1,88	medium_impact	0,02	0,34	0,8	15,9	13,46	N	0,38	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11051	11051	A	T	MI.16932	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	292	98	M	L	Ata/Tta	-10,55	0	0	benign	0,33	neutral	1	neutral	1,74	neutral	2,5	neutral	-0,57	low_impact	1,16	neutral	0,68	neutral	0,95	deleterious	0,57	7,94	0,17	0,45	NA	NA	neutral	0,22	neutral	0,29	neutral	0,16	7	neutral	0,33	deleterious	0,84	neutral	-6	deleterious	0,52	medium_impact	-0,43	high_impact	1,88	medium_impact	0,02	0,34	0,8	15,9	13,46	N	0,39	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11051	11051	A	G	MI.16933	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	292	98	M	V	Ata/Gta	-10,55	0	0	possibly_damaging	0,44	neutral	0,16	neutral	1,67	neutral	-0,06	neutral	-1,87	medium_impact	2,52	neutral	0,79	neutral	0,76	deleterious	2,64	20,4	0,14	0,4	NA	NA	neutral	0,42	neutral	0,48	neutral	0,18	6	neutral	0,82	neutral	0,36	NA	0	deleterious	0,62	medium_impact	-0,62	medium_impact	-0,2	medium_impact	1,37	0,39	0,8	15,9	13,46	N	0,44	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11052	11052	T	A	MI.16934	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	293	98	M	K	aTa/aAa	0,98	0	0	possibly_damaging	0,64	deleterious	0,03	neutral	1,49	neutral	-2,81	deleterious	-3,7	medium_impact	3,08	neutral	0,68	neutral	0,45	deleterious	3,77	23,4	0,02	0,35	NA	NA	disease	0,69	disease	0,68	disease	0,73	5	neutral	0,97	neutral	0,2	deleterious	4	deleterious	0,78	medium_impact	-0,95	medium_impact	-0,64	medium_impact	1,92	0,23	0,8	15,9	13,46	N	0,39	N	0,9	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11052	11052	T	C	MI.16935	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	293	98	M	T	aTa/aCa	0,98	0	0	benign	0,06	neutral	0,27	neutral	1,64	neutral	-1,14	deleterious	-3,1	low_impact	1,88	neutral	0,69	neutral	0,95	neutral	1,49	13,24	0,09	0,35	NA	NA	neutral	0,2	neutral	0,33	neutral	0,17	7	neutral	0,7	deleterious	0,61	neutral	-6	deleterious	0,67	medium_impact	0,41	medium_impact	-0,04	medium_impact	0,73	0,1	0,8	15,9	13,46	P	0,5	N	0,38	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11053	11053	A	T	MI.16936	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	294	98	M	I	atA/atT	1,91	0,02	0	possibly_damaging	0,44	neutral	0,22	neutral	1,59	neutral	-0,09	neutral	-1,6	medium_impact	2,27	neutral	0,75	neutral	0,75	deleterious	3,3	22,9	0,18	0,45	NA	NA	neutral	0,42	neutral	0,31	neutral	0,16	7	neutral	0,75	neutral	0,39	NA	0	deleterious	0,67	medium_impact	-0,62	medium_impact	-0,11	medium_impact	1,12	0,34	0,8	15,9	13,46	N	0,48	N	0,52	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11053	11053	A	C	MI.16937	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	294	98	M	I	atA/atC	1,91	0,02	0	possibly_damaging	0,44	neutral	0,22	neutral	1,59	neutral	-0,09	neutral	-1,6	medium_impact	2,27	neutral	0,75	neutral	0,75	deleterious	3,26	22,8	0,18	0,45	NA	NA	neutral	0,42	neutral	0,31	neutral	0,16	7	neutral	0,75	neutral	0,39	NA	0	deleterious	0,67	medium_impact	-0,62	medium_impact	-0,11	medium_impact	1,12	0,34	0,8	15,9	13,46	N	0,48	N	0,52	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11054	11054	C	A	MI.16938	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	295	99	L	M	Cta/Ata	-3,63	0	0	benign	0,22	neutral	0,13	neutral	1,3	neutral	-2,8	neutral	-1,22	low_impact	1,28	neutral	0,77	neutral	0,81	deleterious	2,37	18,6	0,21	0,45	NA	NA	neutral	0,38	neutral	0,25	neutral	0,2	6	neutral	0,85	neutral	0,46	neutral	-6	deleterious	0,75	medium_impact	-0,2	medium_impact	-0,26	medium_impact	0,14	0,36	0,8	20,7	24,68	N	0,41	N	0,08	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11054	11054	C	G	MI.16939	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	295	99	L	V	Cta/Gta	-3,63	0	0	possibly_damaging	0,64	neutral	0,33	neutral	1,46	neutral	-2,23	neutral	-2,12	medium_impact	2,67	neutral	0,69	neutral	0,57	deleterious	3,28	22,8	0,17	0,45	NA	NA	neutral	0,45	neutral	0,31	neutral	0,23	5	neutral	0,72	neutral	0,35	NA	0	deleterious	0,77	medium_impact	-0,95	medium_impact	0,03	medium_impact	1,52	0,44	0,8	20,7	24,68	N	0,42	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8484	8484	A	C	MI.1694	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	119	40	K	T	aAg/aCg	1,52	0	0	benign	0,2	neutral	0,59	neutral	1,92	neutral	-0,57	deleterious	-4,25	medium_impact	2,19	neutral	0,99	neutral	0,87	deleterious	0,52	7,61	0,45672233	0,85	neutral	0,26	neutral	0,49	neutral	0,39	neutral	0,38	2	neutral	0,3	deleterious	0,7	neutral	-3	neutral	0,29	medium_impact	-0,18	medium_impact	0,38	medium_impact	0,78	0,4	0,85	NA	NA	N	0,4	N	0,34	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11055	11055	T	A	MI.16940	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	296	99	L	Q	cTa/cAa	-1,09	0	0	probably_damaging	0,96	deleterious	0,04	neutral	1,28	deleterious	-5,33	deleterious	-4,33	medium_impact	3,23	neutral	0,67	neutral	0,4	deleterious	4,07	23,7	0,04	0,35	NA	NA	disease	0,72	neutral	0,39	disease	0,52	0	deleterious	0,99	neutral	0,04	deleterious	5	deleterious	0,81	low_impact	-2,01	medium_impact	-0,57	high_impact	2,07	0,27	0,8	20,7	24,68	N	0,44	N	0,86	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11055	11055	T	G	MI.16941	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	296	99	L	R	cTa/cGa	-1,09	0	0	probably_damaging	0,96	deleterious	0,01	neutral	1,26	deleterious	-5,23	deleterious	-4,38	medium_impact	3,23	damaging	0,57	neutral	0,36	deleterious	4,05	23,7	0,02	0,35	NA	NA	disease	0,85	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,89	low_impact	-2,01	medium_impact	-0,92	high_impact	2,07	0,12	0,8	20,7	24,68	N	0,33	N	0,97	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11055	11055	T	C	MI.16942	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	296	99	L	P	cTa/cCa	-1,09	0	0	probably_damaging	0,98	deleterious	0,01	neutral	1,25	deleterious	-5,77	deleterious	-5,15	medium_impact	3,23	damaging	0,55	neutral	0,39	deleterious	3,84	23,4	0,02	0,35	NA	NA	disease	0,84	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,89	low_impact	-2,31	medium_impact	-0,92	high_impact	2,07	0,33	0,8	20,7	24,68	N	0,33	N	0,96	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11057	11057	A	G	MI.16943	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	298	100	I	V	Atc/Gtc	-4,09	0	0	benign	0,08	neutral	0,41	neutral	1,54	neutral	0,25	neutral	-0,3	neutral_impact	0,5	neutral	0,8	neutral	0,99	neutral	1,47	13,13	0,34	0,5	NA	NA	neutral	0,21	neutral	0,2	neutral	0,21	6	neutral	0,54	deleterious	0,67	neutral	-6	deleterious	0,63	medium_impact	0,28	medium_impact	0,11	medium_impact	-0,63	0,31	0,8	47,49	9,25	N	0,45	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11057	11057	A	T	MI.16944	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	298	100	I	F	Atc/Ttc	-4,09	0	0	probably_damaging	0,96	neutral	0,31	neutral	1,39	neutral	-0,21	deleterious	-2,71	medium_impact	2,25	neutral	0,75	neutral	0,48	deleterious	3,64	23,2	0,16	0,45	NA	NA	disease	0,63	neutral	0,26	neutral	0,48	0	neutral	0,96	neutral	0,18	deleterious	1	deleterious	0,76	low_impact	-2,01	medium_impact	0,01	medium_impact	1,1	0,38	0,8	47,49	9,25	N	0,42	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11057	11057	A	C	MI.16945	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	298	100	I	L	Atc/Ctc	-4,09	0	0	possibly_damaging	0,52	neutral	1	neutral	1,57	neutral	2,11	neutral	-1,29	medium_impact	2,8	neutral	0,8	neutral	0,68	deleterious	3,62	23,2	0,21	0,45	NA	NA	neutral	0,49	neutral	0,27	neutral	0,4	2	neutral	0,51	deleterious	0,74	NA	0	deleterious	0,68	medium_impact	-0,75	high_impact	1,88	medium_impact	1,64	0,41	0,8	47,49	9,25	N	0,33	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11058	11058	T	G	MI.16946	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	299	100	I	S	aTc/aGc	-0,4	0	0	probably_damaging	0,94	neutral	0,28	neutral	1,39	neutral	-0,4	deleterious	-3,52	medium_impact	2,25	neutral	0,8	neutral	0,76	deleterious	4,11	23,7	0,05	0,35	NA	NA	disease	0,71	neutral	0,31	disease	0,53	1	neutral	0,95	neutral	0,17	deleterious	1	deleterious	0,77	low_impact	-1,84	medium_impact	-0,03	medium_impact	1,1	0,16	0,8	47,49	9,25	N	0,36	N	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11058	11058	T	A	MI.16947	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	299	100	I	N	aTc/aAc	-0,4	0	0	probably_damaging	0,98	neutral	0,12	neutral	1,35	neutral	-1,75	deleterious	-4,39	medium_impact	2,8	neutral	0,73	neutral	0,45	deleterious	4,49	24,3	0,09	0,35	NA	NA	disease	0,74	neutral	0,5	disease	0,56	1	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,78	low_impact	-2,31	medium_impact	-0,28	medium_impact	1,64	0,15	0,8	47,49	9,25	N	0,39	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11058	11058	T	C	MI.16948	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	299	100	I	T	aTc/aCc	-0,4	0	0	possibly_damaging	0,83	neutral	0,34	neutral	1,45	neutral	-0,66	deleterious	-2,51	low_impact	1,06	neutral	0,73	neutral	0,98	deleterious	1,83	15,17	0,12	0,4	NA	NA	neutral	0,21	neutral	0,23	neutral	0,2	6	neutral	0,85	neutral	0,26	neutral	-3	deleterious	0,69	low_impact	-1,37	medium_impact	0,04	medium_impact	-0,08	0,25	0,8	47,49	9,25	N	0,42	N	0,95	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11059	11059	C	A	MI.16949	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	300	100	I	M	atC/atA	0,52	0	0,01	probably_damaging	0,96	neutral	0,17	neutral	1,4	neutral	-0,76	neutral	-1,83	medium_impact	2,8	neutral	0,79	neutral	0,6	deleterious	3,68	23,3	0,26	0,45	NA	NA	neutral	0,49	neutral	0,23	neutral	0,35	3	neutral	0,97	neutral	0,11	deleterious	1	deleterious	0,73	low_impact	-2,01	medium_impact	-0,18	medium_impact	1,64	0,53	0,8	47,49	9,25	N	0,42	N	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8485	8485	G	C	MI.1695	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	120	40	K	N	aaG/aaC	-3,8	0	0,01	possibly_damaging	0,44	neutral	0,58	neutral	1,92	neutral	-0,6	deleterious	-3,81	medium_impact	2,51	neutral	0,98	neutral	0,8	deleterious	2,28	18,05	0,7892424	0,85	neutral	0,45	neutral	0,43	neutral	0,42	neutral	0,23	5	neutral	0,41	deleterious	0,57	NA	0	neutral	0,39	medium_impact	-0,66	medium_impact	0,37	medium_impact	1,05	0,64	0,85	NA	NA	N	0,36	N	0,56	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11059	11059	C	G	MI.16950	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	300	100	I	M	atC/atG	0,52	0	0,01	probably_damaging	0,96	neutral	0,17	neutral	1,4	neutral	-0,76	neutral	-1,83	medium_impact	2,8	neutral	0,79	neutral	0,6	deleterious	3,28	22,8	0,26	0,45	NA	NA	neutral	0,49	neutral	0,23	neutral	0,35	3	neutral	0,97	neutral	0,11	deleterious	1	deleterious	0,73	low_impact	-2,01	medium_impact	-0,18	medium_impact	1,64	0,53	0,8	47,49	9,25	N	0,42	N	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11060	11060	T	G	MI.16951	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	301	101	S	A	Tcc/Gcc	-8,47	0	0	benign	0,05	neutral	0,38	neutral	1,59	neutral	0,08	neutral	-0,61	low_impact	1,92	neutral	0,77	neutral	0,81	neutral	-0,33	0,56	0,25	0,45	NA	NA	neutral	0,3	neutral	0,24	neutral	0,19	6	neutral	0,59	deleterious	0,67	neutral	-6	neutral	0,14	medium_impact	0,48	medium_impact	0,08	medium_impact	0,77	0,26	0,8	30,28	19,2	N	0,43	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11060	11060	T	C	MI.16952	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	301	101	S	P	Tcc/Ccc	-8,47	0	0	benign	0,41	neutral	0,11	neutral	1,49	neutral	-2,69	neutral	-2,15	medium_impact	2,48	neutral	0,61	neutral	0,4	deleterious	0,64	8,42	0,05	0,35	NA	NA	disease	0,85	disease	0,63	disease	0,78	6	neutral	0,87	neutral	0,35	neutral	-3	deleterious	0,48	medium_impact	-0,57	medium_impact	-0,31	medium_impact	1,33	0,26	0,8	30,28	19,2	N	0,34	N	0,8	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11060	11060	T	A	MI.16953	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	301	101	S	T	Tcc/Acc	-8,47	0	0	benign	0,01	neutral	0,4	neutral	1,58	neutral	-0,14	neutral	-0,44	low_impact	1,32	neutral	0,81	neutral	0,99	neutral	-0,38	0,42	0,26	0,45	NA	NA	neutral	0,2	neutral	0,19	neutral	0,21	6	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,1	medium_impact	1,16	medium_impact	0,1	medium_impact	0,18	0,42	0,8	30,28	19,2	N	0,5	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11061	11061	C	T	MI.16954	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	302	101	S	F	tCc/tTc	-5,93	0	0,01	benign	0	neutral	1	neutral	1,61	neutral	0,29	neutral	-1,23	neutral_impact	0,63	neutral	0,78	neutral	0,81	deleterious	-0,05	2,14	0,08	0,35	NA	NA	disease	0,51	neutral	0,29	neutral	0,42	2	neutral	0	deleterious	1	neutral	-6	neutral	0,31	high_impact	2,1	high_impact	1,88	medium_impact	-0,5	0,13	0,8	30,28	19,2	N	0,23	N	0,62	polymorphism	1	0,03	rs879204439	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11061	11061	C	G	MI.16955	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	302	101	S	C	tCc/tGc	-5,93	0	0,01	benign	0,01	neutral	0,11	neutral	1,5	neutral	-1,97	neutral	-1,41	medium_impact	2,13	neutral	0,77	neutral	0,47	neutral	1,77	14,79	0,07	0,35	NA	NA	disease	0,65	neutral	0,49	neutral	0,49	0	neutral	0,89	deleterious	0,55	neutral	-3	deleterious	0,57	medium_impact	1,16	medium_impact	-0,31	medium_impact	0,98	0,22	0,8	30,28	19,2	N	0,35	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11061	11061	C	A	MI.16956	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	302	101	S	Y	tCc/tAc	-5,93	0	0,01	benign	0,17	neutral	0,56	neutral	1,52	neutral	-1,44	neutral	-1,64	medium_impact	2,13	neutral	0,81	neutral	0,62	neutral	-0,4	0,38	0,06	0,35	NA	NA	disease	0,69	neutral	0,45	neutral	0,5	0	neutral	0,33	deleterious	0,7	neutral	-3	deleterious	0,54	medium_impact	-0,07	medium_impact	0,26	medium_impact	0,98	0,2	0,8	30,28	19,2	N	0,21	N	0,75	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11063	11063	C	A	MI.16957	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	304	102	L	M	Cta/Ata	-11,01	0	0	probably_damaging	1	neutral	0,14	neutral	0,34	deleterious	-4,43	neutral	-1,55	medium_impact	3,19	damaging	0,49	damaging	0,1	deleterious	3,64	23,2	0,28	0,45	NA	NA	disease	0,53	disease	0,57	disease	0,56	1	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,24	high_impact	2,03	0,49	0,8	46,62	9,41	N	0,36	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11063	11063	C	G	MI.16958	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	304	102	L	V	Cta/Gta	-11,01	0	0	probably_damaging	1	neutral	0,06	neutral	0,34	deleterious	-4,36	neutral	-2,32	medium_impact	3,19	damaging	0,59	damaging	0,17	deleterious	3,3	22,9	0,25	0,45	NA	NA	disease	0,51	disease	0,59	neutral	0,46	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,47	high_impact	2,03	0,52	0,8	46,62	9,41	N	0,34	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11064	11064	T	A	MI.16959	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	305	102	L	Q	cTa/cAa	-0,86	0	0	probably_damaging	1	deleterious	0	neutral	0,25	deleterious	-7,85	deleterious	-4,64	high_impact	3,54	damaging	0,46	damaging	0,07	deleterious	3,92	23,5	0,05	0,35	NA	NA	disease	0,76	disease	0,65	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	2,38	0,24	0,8	46,62	9,41	N	0,36	N	0,99	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8485	8485	G	T	MI.1696	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	120	40	K	N	aaG/aaT	-3,8	0	0,01	possibly_damaging	0,44	neutral	0,58	neutral	1,92	neutral	-0,6	deleterious	-3,81	medium_impact	2,51	neutral	0,98	neutral	0,8	deleterious	2,41	18,9	0,7892424	0,85	neutral	0,45	neutral	0,43	neutral	0,42	neutral	0,23	5	neutral	0,41	deleterious	0,57	NA	0	neutral	0,39	medium_impact	-0,66	medium_impact	0,37	medium_impact	1,05	0,64	0,85	NA	NA	N	0,36	N	0,56	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11064	11064	T	C	MI.16960	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	305	102	L	P	cTa/cCa	-0,86	0	0	probably_damaging	1	deleterious	0	neutral	0,25	deleterious	-8,34	deleterious	-5,41	high_impact	3,54	damaging	0,41	damaging	0,07	deleterious	3,76	23,3	0,04	0,35	NA	NA	disease	0,8	disease	0,75	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	2,38	0,33	0,8	46,62	9,41	N	0,48	N	0,98	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11064	11064	T	G	MI.16961	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	305	102	L	R	cTa/cGa	-0,86	0	0	probably_damaging	1	deleterious	0	neutral	0,25	deleterious	-7,89	deleterious	-4,64	high_impact	3,54	damaging	0,44	damaging	0,06	deleterious	4,06	23,7	0,03	0,35	NA	NA	disease	0,87	disease	0,76	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,54	low_impact	-1,48	high_impact	2,38	0,13	0,8	46,62	9,41	N	0,45	N	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11066	11066	C	A	MI.16962	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	307	103	Q	K	Caa/Aaa	-20	0	0	probably_damaging	1	neutral	0,29	neutral	1,4	neutral	-2,03	deleterious	-2,99	high_impact	3,51	neutral	0,71	damaging	0,15	deleterious	3,81	23,4	0,22	0,45	NA	NA	disease	0,86	disease	0,74	disease	0,78	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,02	high_impact	2,35	0,35	0,8	46,84	9,32	N	0,37	N	0,98	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11066	11066	C	G	MI.16963	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	307	103	Q	E	Caa/Gaa	-20	0	0	probably_damaging	1	neutral	0,28	neutral	1,4	neutral	-1,99	neutral	-2,22	high_impact	3,51	neutral	0,69	damaging	0,17	deleterious	2,96	22,1	0,33	0,5	NA	NA	disease	0,79	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,03	high_impact	2,35	0,4	0,8	46,84	9,32	N	0,34	N	0,93	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11067	11067	A	G	MI.16964	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	308	103	Q	R	cAa/cGa	5,6	1	0	probably_damaging	1	neutral	0,35	neutral	1,38	neutral	-2,57	deleterious	-2,96	high_impact	3,51	neutral	0,68	damaging	0,15	deleterious	3,07	22,4	0,2	0,45	NA	NA	disease	0,88	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,54	medium_impact	0,05	high_impact	2,35	0,14	0,8	46,84	9,32	P	0,64	P	0,88	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11067	11067	A	C	MI.16965	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	308	103	Q	P	cAa/cCa	5,6	1	0	probably_damaging	1	neutral	0,2	neutral	1,36	deleterious	-3,68	deleterious	-4,51	high_impact	3,51	neutral	0,64	damaging	0,14	deleterious	3	22,2	0,06	0,35	NA	NA	disease	0,9	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-3,54	medium_impact	-0,14	high_impact	2,35	0,35	0,8	46,84	9,32	P	0,63	P	0,97	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11067	11067	A	T	MI.16966	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	308	103	Q	L	cAa/cTa	5,6	1	0	probably_damaging	1	neutral	0,7	neutral	1,59	neutral	0,02	deleterious	-5,28	medium_impact	2,62	neutral	0,68	damaging	0,14	deleterious	3,43	23	0,11	0,4	NA	NA	disease	0,8	disease	0,54	disease	0,51	0	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	0,41	medium_impact	1,47	0,12	0,8	46,84	9,32	N	0,47	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11068	11068	A	C	MI.16967	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	309	103	Q	H	caA/caC	8,59	1	0	probably_damaging	1	neutral	0,54	neutral	1,37	neutral	-2,93	deleterious	-3,43	high_impact	3,51	neutral	0,77	damaging	0,17	deleterious	3,25	22,8	0,24	0,45	NA	NA	disease	0,79	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,24	high_impact	2,35	0,39	0,8	46,84	9,32	N	0,53	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11068	11068	A	T	MI.16968	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	309	103	Q	H	caA/caT	8,59	1	0	probably_damaging	1	neutral	0,54	neutral	1,37	neutral	-2,93	deleterious	-3,43	high_impact	3,51	neutral	0,77	damaging	0,17	deleterious	3,34	22,9	0,24	0,45	NA	NA	disease	0,79	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,54	medium_impact	0,24	high_impact	2,35	0,39	0,8	46,84	9,32	N	0,54	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11069	11069	A	T	MI.16969	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	310	104	I	F	Atc/Ttc	2,14	0,94	0,01	possibly_damaging	0,49	neutral	0,57	neutral	1,45	neutral	0,6	neutral	-1,39	medium_impact	2,02	neutral	0,71	neutral	0,79	deleterious	0,71	8,9	0,18	0,45	NA	NA	neutral	0,43	neutral	0,31	neutral	0,19	6	neutral	0,45	deleterious	0,54	NA	0	deleterious	0,51	medium_impact	-0,7	medium_impact	0,27	medium_impact	0,87	0,4	0,8	24,62	22,4	N	0,38	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8486	8486	C	G	MI.1697	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	121	41	P	A	Ccc/Gcc	-0,8	0	0	benign	0,07	neutral	0,74	neutral	1,55	neutral	-0,86	neutral	-0,73	low_impact	1,08	neutral	0,99	neutral	0,86	neutral	-1,16	0,01	0,58788784	0,85	neutral	0,22	neutral	0,02	neutral	0,39	neutral	0,05	9	neutral	0,17	deleterious	0,84	neutral	-6	neutral	0,1	medium_impact	0,31	medium_impact	0,55	medium_impact	-0,17	0,66	0,85	13,24	9,24	N	0,44	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11069	11069	A	G	MI.16970	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	310	104	I	V	Atc/Gtc	2,14	0,94	0,01	benign	0,01	neutral	0,24	neutral	1,56	neutral	0,13	neutral	-0,1	low_impact	1,78	neutral	0,79	neutral	0,98	neutral	-0,93	0,02	0,43	0,55	NA	NA	neutral	0,15	neutral	0,31	neutral	0,23	5	neutral	0,76	deleterious	0,62	neutral	-6	neutral	0,09	medium_impact	1,16	medium_impact	-0,08	medium_impact	0,64	0,43	0,8	24,62	22,4	N	0,45	N	0,58	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11069	11069	A	C	MI.16971	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	310	104	I	L	Atc/Ctc	2,14	0,94	0,01	benign	0,02	neutral	0,81	neutral	1,7	neutral	1,22	neutral	-0,13	neutral_impact	0,72	neutral	0,71	neutral	0,97	neutral	-0,91	0,02	0,3	0,45	NA	NA	neutral	0,22	neutral	0,23	neutral	0,16	7	neutral	0,15	deleterious	0,9	neutral	-6	neutral	0,13	medium_impact	0,87	medium_impact	0,56	medium_impact	-0,41	0,5	0,8	24,62	22,4	N	0,39	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11070	11070	T	G	MI.16972	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	311	104	I	S	aTc/aGc	-4,78	0	0	benign	0,36	deleterious	0,01	neutral	1,44	neutral	-0,56	neutral	-1,59	medium_impact	2,48	neutral	0,77	neutral	0,81	deleterious	2,25	17,82	0,09	0,35	NA	NA	disease	0,54	neutral	0,44	neutral	0,48	0	deleterious	0,99	neutral	0,33	deleterious	1	neutral	0,31	medium_impact	-0,48	medium_impact	-0,92	medium_impact	1,33	0,2	0,8	24,62	22,4	N	0,39	N	0,93	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11070	11070	T	C	MI.16973	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	311	104	I	T	aTc/aCc	-4,78	0	0	benign	0,02	neutral	0,29	neutral	1,52	neutral	-0,04	neutral	-0,55	neutral_impact	0,68	neutral	0,72	neutral	0,99	neutral	-0,69	0,08	0,19	0,45	NA	NA	neutral	0,17	neutral	0,29	neutral	0,22	6	neutral	0,7	deleterious	0,64	neutral	-6	neutral	0,09	medium_impact	0,87	medium_impact	-0,02	medium_impact	-0,45	0,23	0,8	24,62	22,4	N	0,48	N	0,97	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11070	11070	T	A	MI.16974	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	311	104	I	N	aTc/aAc	-4,78	0	0	possibly_damaging	0,68	deleterious	0,01	neutral	1,38	deleterious	-3,1	deleterious	-2,58	medium_impact	2,83	neutral	0,75	neutral	0,49	deleterious	2,86	21,7	0,2	0,45	NA	NA	disease	0,58	neutral	0,45	neutral	0,49	0	deleterious	0,99	neutral	0,17	deleterious	4	deleterious	0,51	low_impact	-1,03	medium_impact	-0,92	medium_impact	1,67	0,21	0,8	24,62	22,4	N	0,41	N	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11071	11071	C	A	MI.16975	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	312	104	I	M	atC/atA	-0,17	0	0	possibly_damaging	0,75	neutral	0,3	neutral	1,41	neutral	-1,03	neutral	-0,57	medium_impact	2,27	neutral	0,71	neutral	0,75	neutral	1,77	14,82	0,39	0,5	NA	NA	neutral	0,22	neutral	0,29	neutral	0,16	7	neutral	0,8	neutral	0,28	NA	0	deleterious	0,5	low_impact	-1,17	medium_impact	0	medium_impact	1,12	0,62	0,8	24,62	22,4	N	0,5	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11071	11071	C	G	MI.16976	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	312	104	I	M	atC/atG	-0,17	0	0	possibly_damaging	0,75	neutral	0,3	neutral	1,41	neutral	-1,03	neutral	-0,57	medium_impact	2,27	neutral	0,71	neutral	0,75	neutral	1,37	12,63	0,39	0,5	NA	NA	neutral	0,22	neutral	0,29	neutral	0,16	7	neutral	0,8	neutral	0,28	NA	0	deleterious	0,5	low_impact	-1,17	medium_impact	0	medium_impact	1,12	0,62	0,8	24,62	22,4	N	0,5	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11072	11072	T	A	MI.16977	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	313	105	S	T	Tcc/Acc	-13,08	0	0	benign	0,04	neutral	0,15	neutral	1,54	neutral	-0,98	neutral	-0,27	neutral_impact	0,56	neutral	0,7	neutral	0,84	deleterious	2,53	19,68	0,32	0,5	NA	NA	neutral	0,26	neutral	0,35	neutral	0,16	7	neutral	0,84	deleterious	0,56	neutral	-6	deleterious	0,69	medium_impact	0,58	medium_impact	-0,22	medium_impact	-0,57	0,56	0,8	27,67	26,85	N	0,49	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11072	11072	T	C	MI.16978	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	313	105	S	P	Tcc/Ccc	-13,08	0	0	possibly_damaging	0,81	deleterious	0,03	neutral	1,43	deleterious	-3,85	neutral	-1,85	medium_impact	2,11	damaging	0,52	neutral	0,44	deleterious	3,8	23,4	0,04	0,35	NA	NA	disease	0,86	disease	0,66	disease	0,81	6	deleterious	0,98	neutral	0,11	deleterious	4	deleterious	0,84	low_impact	-1,31	medium_impact	-0,64	medium_impact	0,96	0,23	0,8	27,67	26,85	N	0,4	N	0,76	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11072	11072	T	G	MI.16979	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	313	105	S	A	Tcc/Gcc	-13,08	0	0	benign	0,36	neutral	0,35	neutral	1,59	neutral	0,55	neutral	-0,24	low_impact	1,07	neutral	0,77	neutral	0,84	deleterious	2,41	18,91	0,3	0,45	NA	NA	neutral	0,26	neutral	0,35	neutral	0,16	7	neutral	0,58	deleterious	0,5	neutral	-6	deleterious	0,69	medium_impact	-0,48	medium_impact	0,05	medium_impact	-0,07	0,41	0,8	27,67	26,85	N	0,41	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8486	8486	C	T	MI.1698	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	121	41	P	S	Ccc/Tcc	-0,8	0	0	benign	0,07	neutral	0,68	neutral	1,55	neutral	-0,66	neutral	-0,44	neutral_impact	-0,02	neutral	0,99	neutral	0,97	neutral	-0,43	0,33	0,68116519	0,85	neutral	0,14	neutral	0,03	neutral	0,36	neutral	0,03	9	neutral	0,23	deleterious	0,81	neutral	-6	neutral	0,09	medium_impact	0,31	medium_impact	0,48	low_impact	-1,12	0,27	0,85	13,24	9,24	N	0,44	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11073	11073	C	G	MI.16980	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	314	105	S	C	tCc/tGc	-0,63	0	0	probably_damaging	0,95	neutral	0,09	neutral	1,44	deleterious	-3,62	neutral	-0,73	low_impact	1,76	neutral	0,74	neutral	0,53	deleterious	3,45	23	0,07	0,35	NA	NA	disease	0,67	disease	0,59	disease	0,73	5	deleterious	0,98	neutral	0,07	neutral	-2	deleterious	0,75	low_impact	-1,92	medium_impact	-0,36	medium_impact	0,62	0,28	0,8	27,67	26,85	N	0,4	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11073	11073	C	T	MI.16981	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	314	105	S	F	tCc/tTc	-0,63	0	0	benign	0,04	neutral	1	neutral	1,59	neutral	-2,21	neutral	2,39	neutral_impact	-0,5	neutral	0,7	neutral	0,98	neutral	1,43	12,97	0,06	0,35	NA	NA	neutral	0,24	neutral	0,39	neutral	0,16	7	neutral	0,04	deleterious	0,98	neutral	-6	deleterious	0,7	medium_impact	0,58	high_impact	1,88	low_impact	-1,62	0,11	0,8	27,67	26,85	N	0,3	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11073	11073	C	A	MI.16982	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	314	105	S	Y	tCc/tAc	-0,63	0	0	possibly_damaging	0,61	deleterious	0,01	neutral	1,45	deleterious	-3,18	neutral	1,03	medium_impact	2,11	neutral	0,72	neutral	0,59	deleterious	3,99	23,6	0,05	0,35	NA	NA	disease	0,68	disease	0,57	disease	0,72	4	deleterious	0,99	neutral	0,2	deleterious	4	deleterious	0,77	medium_impact	-0,9	medium_impact	-0,92	medium_impact	0,96	0,3	0,8	27,67	26,85	N	0,43	N	0,42	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11075	11075	T	A	MI.16983	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	316	106	L	M	Tta/Ata	-5,47	0	0	probably_damaging	1	deleterious	0,04	neutral	0,03	deleterious	-5,89	neutral	-1,55	medium_impact	3,1	damaging	0,49	damaging	0,09	deleterious	3,52	23,1	0,27	0,45	NA	NA	disease	0,52	disease	0,57	disease	0,63	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,76	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,94	0,38	0,8	47,28	9,38	N	0,35	N	0,9	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11075	11075	T	G	MI.16984	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	316	106	L	V	Tta/Gta	-5,47	0	0	probably_damaging	1	deleterious	0,04	neutral	0,07	deleterious	-5,04	neutral	-2,32	medium_impact	3,44	damaging	0,52	damaging	0,09	deleterious	3,29	22,8	0,28	0,45	NA	NA	disease	0,53	disease	0,59	disease	0,64	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-3,54	medium_impact	-0,57	high_impact	2,28	0,46	0,8	47,28	9,38	N	0,33	N	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11076	11076	T	C	MI.16985	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	317	106	L	S	tTa/tCa	-0,17	0	0	probably_damaging	1	neutral	0,08	neutral	-0,01	deleterious	-7,8	deleterious	-4,64	medium_impact	3,44	damaging	0,47	damaging	0,1	deleterious	3,63	23,2	0,07	0,35	NA	NA	disease	0,7	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,39	high_impact	2,28	0,19	0,8	47,28	9,38	N	0,32	N	0,95	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11076	11076	T	G	MI.16986	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	317	106	L	W	tTa/tGa	-0,17	0	0	probably_damaging	1	deleterious	0	neutral	-0,02	deleterious	-9,45	deleterious	-4,64	medium_impact	3,44	damaging	0,48	damaging	0,06	deleterious	3,62	23,2	0,06	0,35	NA	NA	disease	0,71	disease	0,69	disease	0,68	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,28	0,19	0,8	47,28	9,38	N	0,36	N	0,98	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11077	11077	A	T	MI.16987	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	318	106	L	F	ttA/ttT	5,83	0,88	0	probably_damaging	1	neutral	0,06	neutral	0,02	deleterious	-6,25	deleterious	-3,09	medium_impact	3,44	damaging	0,49	damaging	0,07	deleterious	3,48	23,1	0,18	0,45	NA	NA	disease	0,63	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,47	high_impact	2,28	0,44	0,8	47,28	9,38	N	0,5	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11077	11077	A	C	MI.16988	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	318	106	L	F	ttA/ttC	5,83	0,88	0	probably_damaging	1	neutral	0,06	neutral	0,02	deleterious	-6,25	deleterious	-3,09	medium_impact	3,44	damaging	0,49	damaging	0,07	deleterious	3,34	22,9	0,18	0,45	NA	NA	disease	0,63	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,47	high_impact	2,28	0,44	0,8	47,28	9,38	N	0,49	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11078	11078	A	G	MI.16989	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	319	107	I	V	Att/Gtt	-3,17	0	0	benign	0,08	neutral	0,46	neutral	1,49	neutral	-0,06	neutral	-0,7	medium_impact	2,08	neutral	0,79	neutral	0,92	deleterious	1,83	15,18	0,63	0,7	NA	NA	neutral	0,3	neutral	0,42	neutral	0,16	7	neutral	0,48	deleterious	0,69	neutral	-3	deleterious	0,65	medium_impact	0,28	medium_impact	0,16	medium_impact	0,93	0,4	0,8	22	8,45	N	0,36	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8486	8486	C	A	MI.1699	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	121	41	P	T	Ccc/Acc	-0,8	0	0	benign	0	neutral	0,59	neutral	1,56	neutral	-0,57	neutral	-0,14	neutral_impact	0,21	neutral	1	neutral	0,97	neutral	-0,12	1,6	0,61638548	0,85	neutral	0,16	neutral	0,05	neutral	0,23	neutral	0,04	9	neutral	0,41	deleterious	0,8	neutral	-6	neutral	0,07	high_impact	2,09	medium_impact	0,38	medium_impact	-0,92	0,62	0,85	13,24	9,24	N	0,44	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11078	11078	A	T	MI.16990	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	319	107	I	F	Att/Ttt	-3,17	0	0	probably_damaging	0,96	neutral	0,31	neutral	1,36	neutral	-1,93	deleterious	-2,67	medium_impact	3,31	neutral	0,7	neutral	0,5	deleterious	3,6	23,2	0,22	0,45	NA	NA	disease	0,69	neutral	0,46	disease	0,51	0	neutral	0,96	neutral	0,18	deleterious	1	deleterious	0,79	low_impact	-2,01	medium_impact	0,01	high_impact	2,15	0,48	0,8	22	8,45	N	0,43	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11078	11078	A	C	MI.16991	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	319	107	I	L	Att/Ctt	-3,17	0	0	possibly_damaging	0,52	neutral	0,46	neutral	1,49	neutral	0,8	neutral	-1,32	medium_impact	2,04	neutral	0,74	neutral	0,71	deleterious	3,59	23,2	0,28	0,45	NA	NA	neutral	0,5	neutral	0,38	neutral	0,44	1	neutral	0,54	deleterious	0,47	NA	0	deleterious	0,68	medium_impact	-0,75	medium_impact	0,16	medium_impact	0,89	0,51	0,8	22	8,45	N	0,4	N	0,86	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11079	11079	T	C	MI.16992	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	320	107	I	T	aTt/aCt	0,75	0,15	0	possibly_damaging	0,83	neutral	0,05	neutral	1,33	neutral	-1,84	deleterious	-3,58	medium_impact	2,42	neutral	0,74	neutral	0,72	deleterious	3,29	22,8	0,11	0,4	NA	NA	disease	0,6	neutral	0,48	neutral	0,46	1	neutral	0,97	neutral	0,11	NA	0	deleterious	0,76	low_impact	-1,37	medium_impact	-0,52	medium_impact	1,27	0,2	0,8	22	8,45	N	0,46	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11079	11079	T	G	MI.16993	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	320	107	I	S	aTt/aGt	0,75	0,15	0	probably_damaging	0,94	neutral	0,08	neutral	1,3	neutral	-2,32	deleterious	-4,37	medium_impact	2,97	neutral	0,72	neutral	0,62	deleterious	4,14	23,8	0,03	0,35	NA	NA	disease	0,76	disease	0,54	disease	0,52	0	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,8	low_impact	-1,84	medium_impact	-0,39	medium_impact	1,81	0,16	0,8	22	8,45	N	0,42	N	0,95	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11079	11079	T	A	MI.16994	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	320	107	I	N	aTt/aAt	0,75	0,15	0	probably_damaging	0,98	deleterious	0,01	neutral	1,27	neutral	-1,66	deleterious	-5,14	medium_impact	3,31	neutral	0,66	neutral	0,48	deleterious	4,38	24,1	0,09	0,35	NA	NA	disease	0,78	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,81	low_impact	-2,31	medium_impact	-0,92	high_impact	2,15	0,19	0,8	22	8,45	N	0,4	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11080	11080	T	A	MI.16995	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	321	107	I	M	atT/atA	5,6	0,88	0,01	probably_damaging	0,96	neutral	0,13	neutral	1,32	neutral	-0,94	neutral	-2,05	medium_impact	2,62	neutral	0,73	neutral	0,63	deleterious	3,62	23,2	0,38	0,5	NA	NA	disease	0,55	disease	0,53	neutral	0,47	1	neutral	0,98	neutral	0,09	deleterious	1	deleterious	0,75	low_impact	-2,01	medium_impact	-0,26	medium_impact	1,47	0,49	0,8	22	8,45	P	0,53	P	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11080	11080	T	G	MI.16996	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	321	107	I	M	atT/atG	5,6	0,88	0,01	probably_damaging	0,96	neutral	0,13	neutral	1,32	neutral	-0,94	neutral	-2,05	medium_impact	2,62	neutral	0,73	neutral	0,63	deleterious	3,3	22,8	0,38	0,5	NA	NA	disease	0,55	disease	0,53	neutral	0,47	1	neutral	0,98	neutral	0,09	deleterious	1	deleterious	0,75	low_impact	-2,01	medium_impact	-0,26	medium_impact	1,47	0,49	0,8	22	8,45	P	0,53	P	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11081	11081	A	C	MI.16997	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	322	108	M	L	Ata/Cta	-5,24	0	0	benign	0,01	neutral	1	neutral	1,8	neutral	0,55	neutral	-1,53	neutral_impact	0,57	neutral	0,69	neutral	0,87	neutral	1,3	12,26	0,36	0,5	NA	NA	neutral	0,3	neutral	0,35	neutral	0,17	7	neutral	0,01	deleterious	1	neutral	-6	deleterious	0,51	medium_impact	1,16	high_impact	1,88	medium_impact	-0,56	0,23	0,8	15,9	15,73	N	0,27	N	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11081	11081	A	G	MI.16998	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	322	108	M	V	Ata/Gta	-5,24	0	0	benign	0,18	neutral	0,18	neutral	1,57	neutral	-0,44	deleterious	-2,59	medium_impact	2,56	neutral	0,81	neutral	0,61	deleterious	2,55	19,78	0,28	0,45	NA	NA	disease	0,66	neutral	0,46	neutral	0,48	1	neutral	0,79	deleterious	0,5	neutral	-3	deleterious	0,65	medium_impact	-0,1	medium_impact	-0,17	medium_impact	1,41	0,33	0,8	15,9	15,73	N	0,34	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11081	11081	A	T	MI.16999	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	322	108	M	L	Ata/Tta	-5,24	0	0	benign	0,01	neutral	1	neutral	1,8	neutral	0,55	neutral	-1,53	neutral_impact	0,57	neutral	0,69	neutral	0,87	neutral	1,37	12,63	0,36	0,5	NA	NA	neutral	0,3	neutral	0,35	neutral	0,17	7	neutral	0,01	deleterious	1	neutral	-6	deleterious	0,51	medium_impact	1,16	high_impact	1,88	medium_impact	-0,56	0,23	0,8	15,9	15,73	N	0,27	N	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8534	8534	A	C	MI.17	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	8	3	E	A	gAa/gCa	-0,1	0,06	0	probably_damaging	0,95	neutral	0,6	neutral	4,7	neutral	0,11	neutral	-2,42	neutral_impact	0,72	neutral	0,86	neutral	0,6	deleterious	3,42	23	0,61	0,7	disease	0,54	neutral	0,1	neutral	0,28	neutral	0,35	3	neutral	0,95	neutral	0,33	neutral	-2	deleterious	0,63	low_impact	-1,97	medium_impact	0,39	medium_impact	-0,48	0,8	0,9	15,93	14,48	N	0,25	N	0,74	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8605	8605	C	G	MI.170	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	79	27	P	A	Ccc/Gcc	-6,58	0	0	probably_damaging	1	neutral	0,51	neutral	4,46	neutral	0,91	deleterious	-7	medium_impact	2,82	neutral	0,73	neutral	0,55	deleterious	2,92	21,9	0,35	0,65	neutral	0,44	disease	0,54	disease	0,57	disease	0,57	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,3	medium_impact	1,32	0,61	0,9	48,23	8,81	N	0,31	N	0,79	polymorphism	0,83	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8487	8487	C	T	MI.1700	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	122	41	P	L	cCc/cTc	-6,81	0	0	benign	0,07	neutral	0,75	neutral	1,53	neutral	-1,58	neutral	-0,62	neutral_impact	-0,46	neutral	1	neutral	0,91	deleterious	0,88	9,98	0,62290357	0,85	neutral	0,36	neutral	0,04	neutral	0,38	neutral	0,03	9	neutral	0,16	deleterious	0,84	neutral	-6	neutral	0,11	medium_impact	0,31	medium_impact	0,56	low_impact	-1,49	0,72	0,85	13,24	9,24	N	0,41	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11082	11082	T	C	MI.17000	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	323	108	M	T	aTa/aCa	0,52	0,04	0	benign	0,03	deleterious	0,02	neutral	1,46	neutral	-1,96	deleterious	-4,13	medium_impact	2,56	neutral	0,8	neutral	0,61	deleterious	2,73	21	0,13	0,4	NA	NA	disease	0,64	disease	0,6	disease	0,55	1	neutral	0,98	deleterious	0,5	deleterious	1	deleterious	0,75	medium_impact	0,7	medium_impact	-0,75	medium_impact	1,41	0,1	0,8	15,9	15,73	N	0,4	N	0,9	polymorphism	1	0,11	.	.	.	.	.	.	COSM5655028	.	.	.	.	.	.	.	.
chrM	11082	11082	T	A	MI.17001	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	323	108	M	K	aTa/aAa	0,52	0,04	0	benign	0,34	deleterious	0,01	neutral	1,42	deleterious	-3,59	deleterious	-4,3	medium_impact	2,9	neutral	0,71	neutral	0,37	deleterious	3,71	23,3	0,03	0,35	NA	NA	disease	0,86	disease	0,68	disease	0,79	6	deleterious	0,99	neutral	0,34	deleterious	1	deleterious	0,83	medium_impact	-0,45	medium_impact	-0,92	medium_impact	1,74	0,17	0,8	15,9	15,73	N	0,35	N	0,94	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11083	11083	A	T	MI.17002	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	324	108	M	I	atA/atT	3,75	0,42	0	benign	0,27	neutral	0,21	neutral	1,56	neutral	-0,57	neutral	-2,44	low_impact	1,49	neutral	0,77	neutral	0,65	deleterious	3,28	22,8	0,34	0,5	NA	NA	disease	0,69	neutral	0,43	disease	0,52	0	neutral	0,75	deleterious	0,47	neutral	-6	deleterious	0,71	medium_impact	-0,31	medium_impact	-0,12	medium_impact	0,35	0,34	0,8	15,9	15,73	N	0,39	N	0,83	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11083	11083	A	C	MI.17003	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	324	108	M	I	atA/atC	3,75	0,42	0	benign	0,27	neutral	0,21	neutral	1,56	neutral	-0,57	neutral	-2,44	low_impact	1,49	neutral	0,77	neutral	0,65	deleterious	3,24	22,8	0,34	0,5	NA	NA	disease	0,69	neutral	0,43	disease	0,52	0	neutral	0,75	deleterious	0,47	neutral	-6	deleterious	0,71	medium_impact	-0,31	medium_impact	-0,12	medium_impact	0,35	0,34	0,8	15,9	15,73	N	0,38	N	0,83	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11084	11084	A	T	MI.17004	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	325	109	T	S	Aca/Tca	-0,86	0	0,08	possibly_damaging	0,89	neutral	0,27	neutral	1,17	neutral	-2,5	neutral	-1,67	medium_impact	2,79	neutral	0,72	neutral	0,61	deleterious	3,12	22,6	0,49	0,55	NA	NA	disease	0,65	neutral	0,44	neutral	0,48	1	neutral	0,92	neutral	0,19	NA	0	deleterious	0,76	low_impact	-1,57	medium_impact	-0,04	medium_impact	1,63	0,65	0,8	17,65	20,11	N	0,49	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11084	11084	A	G	MI.17005	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	325	109	T	A	Aca/Gca	-0,86	0	0,08	possibly_damaging	0,81	neutral	1	neutral	1,3	neutral	-1,26	neutral	-1,32	low_impact	1,1	damaging	0,27	neutral	0,76	deleterious	0,62	8,31	0,34	0,5	NA	NA	neutral	0,12	neutral	0,34	neutral	0,21	6	neutral	0,81	deleterious	0,6	neutral	-3	deleterious	0,66	low_impact	-1,31	high_impact	1,88	medium_impact	-0,04	0,28	0,8	17,65	20,11	P	0,94	P	0,59	disease_causing_automatic	0	0,03	rs199476113	Pathogenic	Juvenile_myopathy,_encephalopathy,_lactic_acidosis_AND_stroke	RCV000010355.3	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	A11084G	AD,PD,MELAS	+	+	Reported,P.M.	6
chrM	11084	11084	A	C	MI.17006	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	325	109	T	P	Aca/Cca	-0,86	0	0,08	probably_damaging	0,98	deleterious	0,04	neutral	1,08	deleterious	-5,03	deleterious	-3,22	medium_impact	3,14	neutral	0,84	neutral	0,36	deleterious	3,35	22,9	0,04	0,35	NA	NA	disease	0,92	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,84	low_impact	-2,31	medium_impact	-0,57	medium_impact	1,98	0,4	0,8	17,65	20,11	N	0,39	N	0,97	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11085	11085	C	T	MI.17007	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	326	109	T	M	aCa/aTa	3,52	1	0	possibly_damaging	0,61	neutral	0,06	neutral	1,11	deleterious	-3,82	deleterious	-3,22	medium_impact	3,14	neutral	0,78	neutral	0,55	deleterious	3,84	23,4	0,11	0,4	NA	NA	disease	0,81	disease	0,58	disease	0,75	5	neutral	0,94	neutral	0,23	NA	0	deleterious	0,78	medium_impact	-0,9	medium_impact	-0,47	medium_impact	1,98	0,56	0,8	17,65	20,11	P	0,56	P	0,92	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11085	11085	C	A	MI.17008	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	326	109	T	K	aCa/aAa	3,52	1	0	probably_damaging	0,96	neutral	0,05	neutral	1,1	deleterious	-3,88	deleterious	-3,22	medium_impact	3,14	neutral	0,79	neutral	0,41	deleterious	4,44	24,2	0,07	0,35	NA	NA	disease	0,91	disease	0,73	disease	0,82	6	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,85	low_impact	-2,01	medium_impact	-0,52	medium_impact	1,98	0,46	0,8	17,65	20,11	N	0,51	P	0,93	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11087	11087	T	C	MI.17009	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	328	110	F	L	Ttc/Ctc	-6,16	0	0,01	probably_damaging	1	deleterious	0,01	neutral	2,07	neutral	-1,68	deleterious	-4,63	high_impact	3,68	damaging	0,55	neutral	0,67	deleterious	3,88	23,5	0,16	0,45	NA	NA	disease	0,81	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,54	medium_impact	-0,92	high_impact	2,52	0,66	0,8	46,84	9,26	N	0,41	N	0,91	polymorphism	1	0,25	rs28433448	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8487	8487	C	A	MI.1701	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	122	41	P	H	cCc/cAc	-6,81	0	0	possibly_damaging	0,73	neutral	0,58	neutral	1,55	neutral	-0,77	neutral	-1,86	low_impact	1,32	neutral	0,98	neutral	0,67	deleterious	2,46	19,18	0,63950197	0,85	neutral	0,44	neutral	0,06	disease	0,53	neutral	0,14	7	neutral	0,69	neutral	0,43	neutral	-3	deleterious	0,46	low_impact	-1,17	medium_impact	0,37	medium_impact	0,03	0,5	0,85	13,24	9,24	N	0,41	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11087	11087	T	G	MI.17010	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	328	110	F	V	Ttc/Gtc	-6,16	0	0,01	probably_damaging	1	deleterious	0	neutral	2,36	neutral	-0,33	deleterious	-5,41	high_impact	4,24	neutral	0,61	neutral	0,65	deleterious	3,96	23,6	0,09	0,35	NA	NA	disease	0,87	disease	0,63	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,07	0,35	0,8	46,84	9,26	N	0,45	N	0,96	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11087	11087	T	A	MI.17011	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	328	110	F	I	Ttc/Atc	-6,16	0	0,01	probably_damaging	1	deleterious	0	neutral	2,06	neutral	-1,92	deleterious	-4,63	high_impact	4,93	neutral	0,63	neutral	0,73	deleterious	4,25	23,9	0,13	0,4	NA	NA	disease	0,86	disease	0,69	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,75	0,41	0,8	46,84	9,26	P	0,71	P	0,96	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11088	11088	T	A	MI.17012	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	329	110	F	Y	tTc/tAc	7,44	1	0	probably_damaging	1	neutral	0,05	neutral	1,96	deleterious	-4,17	neutral	-2,32	high_impact	4,58	neutral	0,66	neutral	0,58	deleterious	4,2	23,9	0,14	0,4	NA	NA	disease	0,77	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,83	low_impact	-3,54	medium_impact	-0,52	high_impact	3,41	0,62	0,8	46,84	9,26	P	0,68	P	0,88	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11088	11088	T	C	MI.17013	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	329	110	F	S	tTc/tCc	7,44	1	0	probably_damaging	1	deleterious	0	neutral	1,98	deleterious	-3,06	deleterious	-6,18	high_impact	4,93	damaging	0,59	neutral	0,78	deleterious	4,16	23,8	0,03	0,35	NA	NA	disease	0,84	disease	0,7	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,75	0,2	0,8	46,84	9,26	P	0,66	P	0,95	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11088	11088	T	G	MI.17014	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	329	110	F	C	tTc/tGc	7,44	1	0	probably_damaging	1	deleterious	0	neutral	1,95	deleterious	-4,69	deleterious	-6,18	high_impact	4,93	neutral	0,66	neutral	0,59	deleterious	3,96	23,6	0,03	0,35	NA	NA	disease	0,85	disease	0,73	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,75	0,31	0,8	46,84	9,26	P	0,65	P	0,99	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11089	11089	C	A	MI.17015	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	330	110	F	L	ttC/ttA	5,83	1	0	probably_damaging	1	deleterious	0,01	neutral	2,07	neutral	-1,68	deleterious	-4,63	high_impact	3,68	damaging	0,55	neutral	0,67	deleterious	4,43	24,2	0,16	0,45	NA	NA	disease	0,81	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,54	medium_impact	-0,92	high_impact	2,52	0,66	0,8	46,84	9,26	P	0,62	P	0,91	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11089	11089	C	G	MI.17016	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	330	110	F	L	ttC/ttG	5,83	1	0	probably_damaging	1	deleterious	0,01	neutral	2,07	neutral	-1,68	deleterious	-4,63	high_impact	3,68	damaging	0,55	neutral	0,67	deleterious	4,14	23,8	0,16	0,45	NA	NA	disease	0,81	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,54	medium_impact	-0,92	high_impact	2,52	0,66	0,8	46,84	9,26	P	0,62	P	0,91	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11090	11090	A	T	MI.17017	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	331	111	T	S	Aca/Tca	-4,32	0	0	benign	0,01	neutral	1	neutral	2,25	neutral	0	neutral	0,04	neutral_impact	-1,35	neutral	0,76	neutral	1	deleterious	0,38	6,4	0,37	0,5	NA	NA	neutral	0,09	neutral	0,21	neutral	0,23	5	neutral	0,01	deleterious	1	neutral	-6	deleterious	0,66	medium_impact	1,16	high_impact	1,88	low_impact	-2,46	0,68	0,85	25,93	24,56	N	0,31	N	0	polymorphism	1	0	.	.	.	.	.	pituitary adenoma	.	.	.	.	.	.	.	.	.
chrM	11090	11090	A	G	MI.17018	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	331	111	T	A	Aca/Gca	-4,32	0	0	benign	0,12	neutral	0,32	neutral	2,17	neutral	-0,27	neutral	-1,06	neutral_impact	0,41	neutral	0,72	neutral	0,96	deleterious	2,08	16,75	0,22	0,45	NA	NA	neutral	0,47	neutral	0,36	neutral	0,25	5	neutral	0,63	deleterious	0,6	neutral	-6	deleterious	0,73	medium_impact	0,1	medium_impact	0,02	medium_impact	-0,72	0,36	0,8	25,93	24,56	N	0,4	N	0,22	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11090	11090	A	C	MI.17019	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	331	111	T	P	Aca/Cca	-4,32	0	0	possibly_damaging	0,51	neutral	0,11	neutral	2,05	deleterious	-3,87	neutral	-2,4	medium_impact	2,25	neutral	0,71	neutral	0,39	deleterious	3,33	22,9	0,05	0,35	NA	NA	disease	0,9	disease	0,71	disease	0,82	6	neutral	0,88	neutral	0,3	NA	0	deleterious	0,85	medium_impact	-0,73	medium_impact	-0,31	medium_impact	1,1	0,44	0,8	25,93	24,56	N	0,34	N	0,68	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8487	8487	C	G	MI.1702	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	122	41	P	R	cCc/cGc	-6,81	0	0	benign	0,29	neutral	0,5	neutral	1,8	neutral	1,84	neutral	-1,69	low_impact	1,77	neutral	1	neutral	0,4	neutral	-0,1	1,72	0,54615447	0,85	neutral	0,29	neutral	0,08	neutral	0,48	neutral	0,05	9	neutral	0,4	deleterious	0,61	neutral	-6	neutral	0,22	medium_impact	-0,39	medium_impact	0,29	medium_impact	0,42	0,55	0,85	13,24	9,24	N	0,44	N	0,34	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11091	11091	C	T	MI.17020	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	332	111	T	M	aCa/aTa	-1,78	0	0	benign	0,01	neutral	0,29	neutral	2,11	neutral	-1,28	neutral	-2,45	neutral_impact	0,02	neutral	0,74	neutral	0,75	deleterious	2,73	21	0,13	0,4	NA	NA	disease	0,62	neutral	0,36	neutral	0,47	1	neutral	0,7	deleterious	0,64	neutral	-6	deleterious	0,76	medium_impact	1,16	medium_impact	-0,02	low_impact	-1,11	0,62	0,8	25,93	24,56	N	0,4	N	0,16	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11091	11091	C	A	MI.17021	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	332	111	T	K	aCa/aAa	-1,78	0	0	benign	0,19	neutral	0,16	neutral	2,06	deleterious	-3,52	neutral	-2,08	medium_impact	2,11	neutral	0,73	neutral	0,47	deleterious	4,33	24	0,06	0,35	NA	NA	disease	0,85	disease	0,7	disease	0,81	6	neutral	0,81	deleterious	0,49	neutral	-3	deleterious	0,83	medium_impact	-0,13	medium_impact	-0,2	medium_impact	0,96	0,51	0,8	25,93	24,56	N	0,34	N	0,53	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11093	11093	G	A	MI.17022	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	334	112	A	T	Gcc/Acc	-15,85	0	0	possibly_damaging	0,83	neutral	0,4	neutral	4,26	deleterious	-3,42	deleterious	-2,61	neutral_impact	0,49	neutral	0,75	neutral	0,83	deleterious	3,88	23,5	0,16	0,45	NA	NA	disease	0,67	neutral	0,42	neutral	0,48	0	neutral	0,84	neutral	0,29	neutral	-3	deleterious	0,72	low_impact	-1,37	medium_impact	0,1	medium_impact	-0,64	0,75	0,85	16,12	14,73	N	0,39	N	0,87	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11093	11093	G	T	MI.17023	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	334	112	A	S	Gcc/Tcc	-15,85	0	0	benign	0,2	neutral	0,86	neutral	5,06	neutral	1,2	neutral	-1,88	neutral_impact	0,56	neutral	0,75	neutral	0,85	deleterious	1,92	15,7	0,23	0,45	NA	NA	neutral	0,44	neutral	0,37	neutral	0,2	6	neutral	0,09	deleterious	0,83	neutral	-6	deleterious	0,6	medium_impact	-0,15	medium_impact	0,64	medium_impact	-0,57	0,57	0,8	16,12	14,73	N	0,32	N	0,32	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11093	11093	G	C	MI.17024	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	334	112	A	P	Gcc/Ccc	-15,85	0	0	probably_damaging	0,96	neutral	0,09	neutral	4,26	deleterious	-3,46	deleterious	-3,58	medium_impact	3,44	neutral	0,69	neutral	0,37	deleterious	3,69	23,3	0,02	0,35	NA	NA	disease	0,93	disease	0,75	disease	0,87	7	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,88	low_impact	-2,01	medium_impact	-0,36	high_impact	2,28	0,55	0,8	16,12	14,73	N	0,38	N	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11094	11094	C	G	MI.17025	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	335	112	A	G	gCc/gGc	0,75	0,67	0	benign	0,08	deleterious	0	neutral	4,25	deleterious	-3,84	deleterious	-2,87	medium_impact	2,89	neutral	0,77	neutral	0,65	deleterious	1,9	15,61	0,17	0,45	NA	NA	disease	0,85	disease	0,63	disease	0,74	5	deleterious	1	neutral	0,46	deleterious	1	neutral	0,27	medium_impact	0,28	low_impact	-1,48	medium_impact	1,73	0,68	0,85	16,12	14,73	N	0,33	N	0,65	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11094	11094	C	A	MI.17026	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	335	112	A	D	gCc/gAc	0,75	0,67	0	possibly_damaging	0,89	deleterious	0	neutral	4,23	deleterious	-5,35	deleterious	-4,21	medium_impact	3,44	neutral	0,71	neutral	0,4	deleterious	4,39	24,1	0,02	0,35	NA	NA	disease	0,93	disease	0,74	disease	0,86	7	deleterious	1	neutral	0,06	deleterious	4	deleterious	0,84	low_impact	-1,57	low_impact	-1,48	high_impact	2,28	0,34	0,8	16,12	14,73	N	0,42	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11094	11094	C	T	MI.17027	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	335	112	A	V	gCc/gTc	0,75	0,67	0	possibly_damaging	0,88	neutral	0,44	neutral	4,3	neutral	-2,53	deleterious	-2,87	low_impact	0,82	neutral	0,74	neutral	0,64	deleterious	4,11	23,7	0,07	0,35	NA	NA	disease	0,85	disease	0,58	disease	0,55	1	neutral	0,87	neutral	0,28	neutral	-3	deleterious	0,78	low_impact	-1,53	medium_impact	0,14	medium_impact	-0,32	0,67	0,85	16,12	14,73	N	0,32	N	0,82	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11096	11096	A	G	MI.17028	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	337	113	T	A	Aca/Gca	-12,16	0	0	benign	0,05	neutral	0,21	neutral	4,65	neutral	-0,21	deleterious	-2,67	medium_impact	2,42	neutral	0,78	neutral	0,86	neutral	1,38	12,66	0,24	0,45	NA	NA	disease	0,63	disease	0,57	disease	0,62	2	neutral	0,77	deleterious	0,58	neutral	-3	neutral	0,2	medium_impact	0,48	medium_impact	-0,12	medium_impact	1,27	0,37	0,8	17,21	15,02	N	0,39	N	0,6	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11096	11096	A	T	MI.17029	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	337	113	T	S	Aca/Tca	-12,16	0	0	benign	0,13	neutral	0,64	neutral	4,77	neutral	-0,13	neutral	-1,78	neutral_impact	0,7	neutral	0,74	neutral	0,95	deleterious	0,21	4,76	0,35	0,5	NA	NA	neutral	0,43	neutral	0,34	neutral	0,19	6	neutral	0,25	deleterious	0,76	neutral	-6	neutral	0,29	medium_impact	0,06	medium_impact	0,34	medium_impact	-0,43	0,58	0,8	17,21	15,02	N	0,34	N	0,06	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8489	8489	A	G	MI.1703	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	124	42	M	V	Ata/Gta	-6,35	0	0	possibly_damaging	0,75	neutral	0,6	neutral	1,23	neutral	-2,4	neutral	-0,36	neutral_impact	0,76	neutral	1	neutral	0,93	neutral	-0,13	1,54	0,70671114	0,85	neutral	0,22	neutral	0,22	neutral	0,35	neutral	0,11	8	neutral	0,71	neutral	0,43	neutral	-3	neutral	0,35	low_impact	-1,21	medium_impact	0,39	medium_impact	-0,45	0,44	0,85	17,65	9,06	N	0,36	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11096	11096	A	C	MI.17030	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	337	113	T	P	Aca/Cca	-12,16	0	0	probably_damaging	0,93	neutral	0,09	neutral	4,61	neutral	-1,7	deleterious	-3,67	medium_impact	2,17	neutral	0,68	neutral	0,4	deleterious	3,06	22,4	0,06	0,35	NA	NA	disease	0,9	disease	0,72	disease	0,8	6	neutral	0,98	neutral	0,08	deleterious	1	deleterious	0,74	low_impact	-1,77	medium_impact	-0,36	medium_impact	1,02	0,3	0,8	17,21	15,02	N	0,35	N	0,98	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11097	11097	C	A	MI.17031	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	338	113	T	K	aCa/aAa	0,06	0	0	possibly_damaging	0,75	neutral	0,14	neutral	4,67	neutral	-0,34	deleterious	-3,49	low_impact	1,84	neutral	0,73	neutral	0,45	deleterious	2,61	20,2	0,11	0,4	NA	NA	disease	0,91	disease	0,71	disease	0,8	6	neutral	0,9	neutral	0,2	neutral	-3	deleterious	0,52	low_impact	-1,17	medium_impact	-0,24	medium_impact	0,69	0,51	0,8	17,21	15,02	N	0,35	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11097	11097	C	T	MI.17032	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	338	113	T	M	aCa/aTa	0,06	0	0	probably_damaging	0,96	neutral	0,42	neutral	4,61	neutral	-2,65	deleterious	-3,38	low_impact	1	neutral	0,8	neutral	0,93	deleterious	2,69	20,7	0,11	0,4	NA	NA	disease	0,65	neutral	0,39	neutral	0,47	1	neutral	0,96	neutral	0,23	neutral	-2	deleterious	0,7	low_impact	-2,01	medium_impact	0,12	medium_impact	-0,14	0,55	0,8	17,21	15,02	N	0,29	N	0,42	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11099	11099	G	A	MI.17033	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	340	114	E	K	Gaa/Aaa	-5,7	0	0	probably_damaging	1	deleterious	0,01	neutral	4,57	neutral	-0,51	deleterious	-3,07	medium_impact	2,05	neutral	0,69	neutral	0,45	deleterious	4,32	24	0,09	0,35	NA	NA	disease	0,9	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,89	low_impact	-3,54	medium_impact	-0,92	medium_impact	0,9	0,82	0,85	46,41	8,56	N	0,39	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11099	11099	G	C	MI.17034	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	340	114	E	Q	Gaa/Caa	-5,7	0	0	probably_damaging	1	deleterious	0,01	neutral	4,56	neutral	-0,95	neutral	-2,29	medium_impact	3,09	neutral	0,71	neutral	0,56	deleterious	3,23	22,8	0,16	0,45	NA	NA	disease	0,73	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,93	0,58	0,8	46,41	8,56	N	0,38	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11100	11100	A	T	MI.17035	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	341	114	E	V	gAa/gTa	3,75	1	0	probably_damaging	1	deleterious	0	neutral	4,53	neutral	-2,24	deleterious	-5,36	medium_impact	3,09	neutral	0,68	neutral	0,57	deleterious	3,96	23,6	0,04	0,35	NA	NA	disease	0,89	disease	0,68	disease	0,77	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	medium_impact	1,93	0,26	0,8	46,41	8,56	P	0,5	N	0,8	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11100	11100	A	C	MI.17036	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	341	114	E	A	gAa/gCa	3,75	1	0	probably_damaging	1	deleterious	0,01	neutral	4,56	neutral	-0,89	deleterious	-4,59	medium_impact	3,09	neutral	0,74	neutral	0,62	deleterious	3,53	23,1	0,08	0,35	NA	NA	disease	0,72	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,82	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,93	0,28	0,8	46,41	8,56	P	0,57	P	0,74	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11100	11100	A	G	MI.17037	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	341	114	E	G	gAa/gGa	3,75	1	0	probably_damaging	1	neutral	0,05	neutral	4,56	neutral	-1,65	deleterious	-5,31	medium_impact	2,4	neutral	0,7	neutral	0,66	deleterious	4,07	23,7	0,11	0,4	NA	NA	disease	0,84	disease	0,68	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,25	0,23	0,8	46,41	8,56	P	0,55	P	0,53	polymorphism	1	0,09	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	11101	11101	A	T	MI.17038	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	342	114	E	D	gaA/gaT	8,59	1	0	probably_damaging	1	neutral	0,42	neutral	4,9	neutral	3,07	neutral	-2,15	neutral_impact	0,18	neutral	0,71	neutral	0,8	deleterious	3,62	23,2	0,21	0,45	NA	NA	disease	0,59	disease	0,51	neutral	0,44	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,81	low_impact	-3,54	medium_impact	0,12	medium_impact	-0,95	0,62	0,8	46,41	8,56	P	0,61	P	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11101	11101	A	C	MI.17039	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	342	114	E	D	gaA/gaC	8,59	1	0	probably_damaging	1	neutral	0,42	neutral	4,9	neutral	3,07	neutral	-2,15	neutral_impact	0,18	neutral	0,71	neutral	0,8	deleterious	3,52	23,1	0,21	0,45	NA	NA	disease	0,59	disease	0,51	neutral	0,44	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,81	low_impact	-3,54	medium_impact	0,12	medium_impact	-0,95	0,62	0,8	46,41	8,56	P	0,6	P	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8489	8489	A	T	MI.1704	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	124	42	M	L	Ata/Tta	-6,35	0	0	possibly_damaging	0,66	neutral	0,79	neutral	1,26	neutral	-1,98	neutral	-0,46	neutral_impact	0,18	neutral	1	neutral	0,94	neutral	1,32	12,36	0,62618842	0,85	neutral	0,12	neutral	0,17	neutral	0,32	neutral	0,07	9	neutral	0,59	deleterious	0,57	neutral	-3	neutral	0,3	low_impact	-1,03	medium_impact	0,62	medium_impact	-0,94	0,53	0,85	17,65	9,06	N	0,36	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11102	11102	C	A	MI.17040	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	343	115	L	M	Cta/Ata	-0,63	0	0	possibly_damaging	0,68	neutral	0,18	neutral	4,03	deleterious	-4,21	neutral	-0,37	medium_impact	2,19	neutral	0,77	neutral	0,83	deleterious	2,43	19,03	0,26	0,45	NA	NA	neutral	0,3	neutral	0,43	neutral	0,18	6	neutral	0,85	neutral	0,25	NA	0	deleterious	0,7	low_impact	-1,03	medium_impact	-0,17	medium_impact	1,04	0,73	0,85	14,6	9,81	N	0,47	N	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11102	11102	C	G	MI.17041	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	343	115	L	V	Cta/Gta	-0,63	0	0	possibly_damaging	0,86	neutral	0,19	neutral	4,15	neutral	-2,31	neutral	-1,22	medium_impact	2,5	neutral	0,7	damaging	0,27	deleterious	2,08	16,71	0,24	0,45	NA	NA	neutral	0,47	disease	0,58	neutral	0,39	2	neutral	0,92	neutral	0,17	NA	0	deleterious	0,76	low_impact	-1,46	medium_impact	-0,15	medium_impact	1,35	0,59	0,8	14,6	9,81	N	0,39	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11103	11103	T	G	MI.17042	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	344	115	L	R	cTa/cGa	-0,63	0	0	probably_damaging	0,98	deleterious	0	neutral	4,01	deleterious	-5,3	deleterious	-3,83	high_impact	4,12	neutral	0,69	damaging	0,1	deleterious	4,07	23,7	0,03	0,35	NA	NA	disease	0,9	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-2,31	low_impact	-1,48	high_impact	2,95	0,15	0,8	14,6	9,81	N	0,46	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11103	11103	T	A	MI.17043	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	344	115	L	Q	cTa/cAa	-0,63	0	0	probably_damaging	0,98	deleterious	0	neutral	4,01	deleterious	-5,47	deleterious	-3,62	high_impact	4,12	neutral	0,71	damaging	0,09	deleterious	4,1	23,7	0,05	0,35	NA	NA	disease	0,74	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,31	low_impact	-1,48	high_impact	2,95	0,26	0,8	14,6	9,81	N	0,38	N	0,94	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11103	11103	T	C	MI.17044	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	344	115	L	P	cTa/cCa	-0,63	0	0	probably_damaging	0,99	deleterious	0	neutral	4	deleterious	-5,87	deleterious	-4,43	high_impact	3,77	neutral	0,64	damaging	0,09	deleterious	3,86	23,5	0,04	0,35	NA	NA	disease	0,84	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,59	low_impact	-1,48	high_impact	2,6	0,28	0,8	14,6	9,81	N	0,41	N	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11105	11105	A	G	MI.17045	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	346	116	I	V	Atc/Gtc	-2,24	0	0	benign	0,4	neutral	0,16	neutral	4,4	neutral	0,16	neutral	-0,62	low_impact	1,16	neutral	0,78	neutral	0,61	neutral	1,04	10,9	0,4	0,5	NA	NA	neutral	0,4	neutral	0,37	neutral	0,19	6	neutral	0,81	neutral	0,38	neutral	-6	neutral	0,15	medium_impact	-0,55	medium_impact	-0,2	medium_impact	0,02	0,62	0,8	11,76	8,95	N	0,36	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11105	11105	A	C	MI.17046	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	346	116	I	L	Atc/Ctc	-2,24	0	0	benign	0,18	neutral	0,93	neutral	4,71	neutral	1,17	neutral	-1,04	neutral_impact	0,42	neutral	0,72	neutral	0,69	deleterious	0,69	8,76	0,23	0,45	NA	NA	neutral	0,48	neutral	0,31	neutral	0,33	3	neutral	0,08	deleterious	0,88	neutral	-6	neutral	0,13	medium_impact	-0,1	medium_impact	0,83	medium_impact	-0,71	0,65	0,8	11,76	8,95	N	0,26	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11105	11105	A	T	MI.17047	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	346	116	I	F	Atc/Ttc	-2,24	0	0	possibly_damaging	0,83	neutral	0,63	neutral	4,46	neutral	1,01	neutral	-2,49	low_impact	1	neutral	0,68	neutral	0,51	neutral	1,78	14,85	0,18	0,45	NA	NA	disease	0,6	neutral	0,39	neutral	0,47	1	neutral	0,8	neutral	0,4	neutral	-3	neutral	0,34	low_impact	-1,37	medium_impact	0,33	medium_impact	-0,14	0,6	0,8	11,76	8,95	N	0,32	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11106	11106	T	C	MI.17048	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	347	116	I	T	aTc/aCc	4,44	0,99	0	possibly_damaging	0,81	neutral	0,2	neutral	4,32	neutral	-2,14	deleterious	-3,1	medium_impact	2,02	neutral	0,75	neutral	0,64	neutral	1,51	13,37	0,08	0,35	NA	NA	neutral	0,44	neutral	0,4	neutral	0,21	6	neutral	0,89	neutral	0,2	NA	0	neutral	0,24	low_impact	-1,31	medium_impact	-0,14	medium_impact	0,87	0,28	0,8	11,76	8,95	P	0,61	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11106	11106	T	G	MI.17049	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	347	116	I	S	aTc/aGc	4,44	0,99	0	possibly_damaging	0,86	deleterious	0,04	neutral	4,31	neutral	-2,47	deleterious	-3,88	medium_impact	2,68	neutral	0,71	neutral	0,5	deleterious	2,33	18,4	0,03	0,35	NA	NA	disease	0,77	neutral	0,44	disease	0,59	2	neutral	0,98	neutral	0,09	deleterious	4	neutral	0,31	low_impact	-1,46	medium_impact	-0,57	medium_impact	1,53	0,24	0,8	11,76	8,95	P	0,57	P	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8489	8489	A	C	MI.1705	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	124	42	M	L	Ata/Cta	-6,35	0	0	possibly_damaging	0,66	neutral	0,79	neutral	1,26	neutral	-1,98	neutral	-0,46	neutral_impact	0,18	neutral	1	neutral	0,94	neutral	1,18	11,64	0,62618842	0,85	neutral	0,12	neutral	0,17	neutral	0,32	neutral	0,07	9	neutral	0,59	deleterious	0,57	neutral	-3	neutral	0,3	low_impact	-1,03	medium_impact	0,62	medium_impact	-0,94	0,53	0,85	17,65	9,06	N	0,36	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11106	11106	T	A	MI.17050	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	347	116	I	N	aTc/aAc	4,44	0,99	0	probably_damaging	0,95	deleterious	0	neutral	4,29	deleterious	-3,93	deleterious	-4,66	medium_impact	3,38	neutral	0,68	neutral	0,44	deleterious	2,81	21,4	0,08	0,35	NA	NA	disease	0,81	disease	0,6	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,5	low_impact	-1,92	low_impact	-1,48	high_impact	2,22	0,31	0,8	11,76	8,95	P	0,54	P	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11107	11107	C	A	MI.17051	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	348	116	I	M	atC/atA	3,75	0,99	0	benign	0,39	neutral	0,4	neutral	4,34	neutral	-1,49	neutral	-1,49	neutral_impact	0,67	neutral	0,75	neutral	0,88	deleterious	0,69	8,79	0,26	0,45	NA	NA	neutral	0,31	neutral	0,31	neutral	0,18	6	neutral	0,54	deleterious	0,51	neutral	-6	neutral	0,12	medium_impact	-0,54	medium_impact	0,1	medium_impact	-0,46	0,51	0,8	11,76	8,95	N	0,49	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11107	11107	C	G	MI.17052	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	348	116	I	M	atC/atG	3,75	0,99	0	benign	0,39	neutral	0,4	neutral	4,34	neutral	-1,49	neutral	-1,49	neutral_impact	0,67	neutral	0,75	neutral	0,88	deleterious	0,19	4,6	0,26	0,45	NA	NA	neutral	0,31	neutral	0,31	neutral	0,18	6	neutral	0,54	deleterious	0,51	neutral	-6	neutral	0,12	medium_impact	-0,54	medium_impact	0,1	medium_impact	-0,46	0,51	0,8	11,76	8,95	N	0,49	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11108	11108	A	C	MI.17053	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	349	117	M	L	Ata/Cta	-7,78	0	0	benign	0	neutral	1	neutral	4,88	neutral	2,16	neutral	-0,24	neutral_impact	-0,18	neutral	0,78	neutral	0,99	neutral	0,98	10,53	0,23	0,45	NA	NA	neutral	0,34	neutral	0,42	neutral	0,17	7	neutral	0	deleterious	1	neutral	-6	deleterious	0,51	high_impact	2,1	high_impact	1,88	low_impact	-1,3	0,21	0,8	38,56	9,77	N	0,3	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11108	11108	A	T	MI.17054	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	349	117	M	L	Ata/Tta	-7,78	0	0	benign	0	neutral	1	neutral	4,88	neutral	2,16	neutral	-0,24	neutral_impact	-0,18	neutral	0,78	neutral	0,99	neutral	1,05	10,92	0,23	0,45	NA	NA	neutral	0,34	neutral	0,42	neutral	0,17	7	neutral	0	deleterious	1	neutral	-6	deleterious	0,51	high_impact	2,1	high_impact	1,88	low_impact	-1,3	0,21	0,8	38,56	9,77	N	0,3	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11108	11108	A	G	MI.17055	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	349	117	M	V	Ata/Gta	-7,78	0	0	benign	0,13	neutral	0,08	neutral	4,7	neutral	0,67	neutral	-1,76	low_impact	1,84	neutral	0,69	neutral	0,59	deleterious	2,57	19,94	0,2	0,45	NA	NA	disease	0,77	disease	0,66	disease	0,7	4	neutral	0,91	deleterious	0,48	neutral	-6	deleterious	0,68	medium_impact	0,06	medium_impact	-0,39	medium_impact	0,69	0,3	0,8	38,56	9,77	N	0,37	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11109	11109	T	A	MI.17056	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	350	117	M	K	aTa/aAa	-5,47	0	0	possibly_damaging	0,49	deleterious	0,04	neutral	4,62	neutral	-1,74	deleterious	-3,65	medium_impact	2,52	neutral	0,7	neutral	0,45	deleterious	3,84	23,4	0,04	0,35	NA	NA	disease	0,9	disease	0,72	disease	0,8	6	neutral	0,96	neutral	0,28	deleterious	4	deleterious	0,84	medium_impact	-0,7	medium_impact	-0,57	medium_impact	1,37	0,18	0,8	38,56	9,77	N	0,36	N	0,91	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11109	11109	T	C	MI.17057	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	350	117	M	T	aTa/aCa	-5,47	0	0	benign	0,41	neutral	0,05	neutral	4,75	neutral	0,88	deleterious	-3,22	medium_impact	2,02	neutral	0,67	neutral	0,65	deleterious	2,85	21,6	0,1	0,4	NA	NA	disease	0,76	disease	0,61	disease	0,69	4	neutral	0,94	neutral	0,32	neutral	-3	deleterious	0,77	medium_impact	-0,57	medium_impact	-0,52	medium_impact	0,87	0,19	0,8	38,56	9,77	N	0,35	N	0,76	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11110	11110	A	T	MI.17058	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	351	117	M	I	atA/atT	4,67	0,69	0	benign	0,08	neutral	0,14	neutral	4,71	neutral	-0,19	neutral	-1,34	low_impact	1,84	neutral	0,69	neutral	0,51	deleterious	3,27	22,8	0,24	0,45	NA	NA	disease	0,8	disease	0,64	disease	0,7	4	neutral	0,85	deleterious	0,53	neutral	-6	deleterious	0,74	medium_impact	0,28	medium_impact	-0,24	medium_impact	0,69	0,21	0,8	38,56	9,77	N	0,42	N	0,55	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11110	11110	A	C	MI.17059	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	351	117	M	I	atA/atC	4,67	0,69	0	benign	0,08	neutral	0,14	neutral	4,71	neutral	-0,19	neutral	-1,34	low_impact	1,84	neutral	0,69	neutral	0,51	deleterious	3,18	22,7	0,24	0,45	NA	NA	disease	0,8	disease	0,64	disease	0,7	4	neutral	0,85	deleterious	0,53	neutral	-6	deleterious	0,74	medium_impact	0,28	medium_impact	-0,24	medium_impact	0,69	0,21	0,8	38,56	9,77	N	0,41	N	0,55	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8490	8490	T	C	MI.1706	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	125	42	M	T	aTa/aCa	-9,59	0	0	possibly_damaging	0,88	neutral	0,75	neutral	1,2	deleterious	-3,05	neutral	-0,17	neutral_impact	-0,86	neutral	1	neutral	0,98	neutral	1,11	11,28	0,7892424	0,85	neutral	0,24	neutral	0,21	neutral	0,24	neutral	0,15	7	neutral	0,86	neutral	0,44	neutral	-3	deleterious	0,53	low_impact	-1,58	medium_impact	0,56	low_impact	-1,83	0,15	0,85	17,65	9,06	N	0,35	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11111	11111	T	G	MI.17060	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	352	118	F	V	Ttt/Gtt	-1,55	0	0	possibly_damaging	0,74	deleterious	0	neutral	4,54	neutral	-2,03	deleterious	-5,09	high_impact	4,12	neutral	0,63	neutral	0,63	deleterious	3,85	23,4	0,06	0,35	NA	NA	disease	0,86	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,82	low_impact	-1,14	low_impact	-1,48	high_impact	2,95	0,34	0,8	45,32	8,57	N	0,47	N	0,96	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11111	11111	T	C	MI.17061	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	352	118	F	L	Ttt/Ctt	-1,55	0	0	benign	0,08	neutral	0,05	neutral	4,62	neutral	0,38	deleterious	-4,31	medium_impact	3,08	neutral	0,62	neutral	0,72	deleterious	3,88	23,5	0,14	0,4	NA	NA	disease	0,81	disease	0,56	disease	0,63	3	neutral	0,95	deleterious	0,49	neutral	-3	deleterious	0,79	medium_impact	0,28	medium_impact	-0,52	medium_impact	1,92	0,51	0,8	45,32	8,57	N	0,48	N	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11111	11111	T	A	MI.17062	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	352	118	F	I	Ttt/Att	-1,55	0	0	possibly_damaging	0,74	deleterious	0	neutral	4,68	neutral	-1,81	deleterious	-4,36	high_impact	4,12	neutral	0,65	neutral	0,66	deleterious	4,24	23,9	0,1	0,4	NA	NA	disease	0,83	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,82	low_impact	-1,14	low_impact	-1,48	high_impact	2,95	0,47	0,8	45,32	8,57	P	0,53	P	0,96	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11112	11112	T	G	MI.17063	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	353	118	F	C	tTt/tGt	4,44	1	0	probably_damaging	0,98	deleterious	0	neutral	4,43	deleterious	-4,99	deleterious	-5,9	high_impact	4,47	neutral	0,68	neutral	0,53	deleterious	4,01	23,6	0,03	0,35	NA	NA	disease	0,86	disease	0,68	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,31	low_impact	-1,48	high_impact	3,3	0,19	0,8	45,32	8,57	P	0,58	P	0,99	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11112	11112	T	A	MI.17064	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	353	118	F	Y	tTt/tAt	4,44	1	0	possibly_damaging	0,89	deleterious	0	neutral	4,45	deleterious	-3,87	neutral	-2,03	high_impact	3,57	neutral	0,66	neutral	0,57	deleterious	4,32	24	0,12	0,4	NA	NA	disease	0,78	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,82	low_impact	-1,57	low_impact	-1,48	high_impact	2,41	0,54	0,8	45,32	8,57	P	0,63	P	0,88	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11112	11112	T	C	MI.17065	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	353	118	F	S	tTt/tCt	4,44	1	0	probably_damaging	0,96	deleterious	0	neutral	4,46	deleterious	-3,51	deleterious	-5,92	high_impact	4,12	neutral	0,7	neutral	0,7	deleterious	4,21	23,9	0,02	0,35	NA	NA	disease	0,84	disease	0,65	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-2,01	low_impact	-1,48	high_impact	2,95	0,34	0,8	45,32	8,57	P	0,55	P	0,93	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11113	11113	T	A	MI.17066	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	354	118	F	L	ttT/ttA	5,6	1	0	benign	0,08	neutral	0,05	neutral	4,62	neutral	0,38	deleterious	-4,31	medium_impact	3,08	neutral	0,62	neutral	0,72	deleterious	4,32	24	0,14	0,4	NA	NA	disease	0,81	disease	0,56	disease	0,63	3	neutral	0,95	deleterious	0,49	neutral	-3	deleterious	0,79	medium_impact	0,28	medium_impact	-0,52	medium_impact	1,92	0,51	0,8	45,32	8,57	P	0,69	P	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11113	11113	T	G	MI.17067	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	354	118	F	L	ttT/ttG	5,6	1	0	benign	0,08	neutral	0,05	neutral	4,62	neutral	0,38	deleterious	-4,31	medium_impact	3,08	neutral	0,62	neutral	0,72	deleterious	4,25	23,9	0,14	0,4	NA	NA	disease	0,81	disease	0,56	disease	0,63	3	neutral	0,95	deleterious	0,49	neutral	-3	deleterious	0,79	medium_impact	0,28	medium_impact	-0,52	medium_impact	1,92	0,51	0,8	45,32	8,57	P	0,69	P	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11114	11114	T	C	MI.17068	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	355	119	Y	H	Tat/Cat	-7,09	0	0	probably_damaging	1	deleterious	0	neutral	4,21	deleterious	-5,78	deleterious	-3,83	high_impact	4,32	neutral	0,66	damaging	0,13	deleterious	3,4	23	0,07	0,35	NA	NA	disease	0,82	disease	0,77	disease	0,77	5	deleterious	1	deleterious	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,15	0,18	0,8	46,41	8,92	N	0,47	N	0,97	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11114	11114	T	G	MI.17069	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	355	119	Y	D	Tat/Gat	-7,09	0	0	probably_damaging	1	deleterious	0	neutral	4,2	deleterious	-7,06	deleterious	-7,6	high_impact	4,32	neutral	0,74	damaging	0,15	deleterious	3,8	23,4	0,03	0,35	NA	NA	disease	0,87	disease	0,76	disease	0,79	6	deleterious	1	deleterious	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,15	0,14	0,8	46,41	8,92	N	0,45	N	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8490	8490	T	A	MI.1707	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	125	42	M	K	aTa/aAa	-9,59	0	0	possibly_damaging	0,88	neutral	0,68	neutral	1,18	deleterious	-3,6	neutral	-1,95	neutral_impact	0,54	neutral	1	neutral	0,72	deleterious	2,65	20,5	0,46643282	0,85	neutral	0,47	neutral	0,37	neutral	0,32	neutral	0,16	7	neutral	0,86	neutral	0,4	neutral	-3	deleterious	0,59	low_impact	-1,58	medium_impact	0,48	medium_impact	-0,64	0,46	0,85	17,65	9,06	N	0,38	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11114	11114	T	A	MI.17070	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	355	119	Y	N	Tat/Aat	-7,09	0	0	probably_damaging	1	deleterious	0	neutral	4,21	deleterious	-5,57	deleterious	-6,86	high_impact	3,98	neutral	0,69	damaging	0,16	deleterious	3,88	23,5	0,04	0,35	NA	NA	disease	0,86	disease	0,68	disease	0,75	5	deleterious	1	deleterious	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,81	0,13	0,8	46,41	8,92	N	0,33	N	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11115	11115	A	C	MI.17071	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	356	119	Y	S	tAt/tCt	7,44	1	0	probably_damaging	1	deleterious	0	neutral	4,22	deleterious	-5,01	deleterious	-6,83	high_impact	4,32	neutral	0,69	damaging	0,17	deleterious	3,61	23,2	0,04	0,35	NA	NA	disease	0,84	disease	0,68	disease	0,75	5	deleterious	1	deleterious	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,15	0,13	0,8	46,41	8,92	P	0,55	P	0,95	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11115	11115	A	G	MI.17072	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	356	119	Y	C	tAt/tGt	7,44	1	0	probably_damaging	1	deleterious	0	neutral	4,23	deleterious	-6,34	deleterious	-6,83	high_impact	4,32	neutral	0,7	damaging	0,12	deleterious	3,45	23	0,03	0,35	NA	NA	disease	0,87	disease	0,73	disease	0,78	6	deleterious	1	deleterious	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,15	0,16	0,8	46,41	8,92	P	0,54	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11115	11115	A	T	MI.17073	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	356	119	Y	F	tAt/tTt	7,44	1	0	probably_damaging	1	neutral	0,09	neutral	4,55	neutral	0,54	deleterious	-2,86	low_impact	1,51	neutral	0,7	neutral	0,33	deleterious	3,25	22,8	0,15	0,4	NA	NA	disease	0,71	neutral	0,48	neutral	0,49	0	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,83	low_impact	-3,54	medium_impact	-0,36	medium_impact	0,37	0,42	0,8	46,41	8,92	P	0,59	P	0,79	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11117	11117	A	C	MI.17074	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	358	120	I	L	Atc/Ctc	-2,24	0	0	benign	0,39	neutral	0,25	neutral	4,69	neutral	0,04	neutral	-1,54	low_impact	1,9	neutral	0,72	neutral	0,51	neutral	1,72	14,52	0,17	0,45	NA	NA	disease	0,58	neutral	0,37	neutral	0,46	1	neutral	0,71	neutral	0,43	neutral	-6	neutral	0,18	medium_impact	-0,54	medium_impact	-0,07	medium_impact	0,75	0,52	0,8	46,19	9,15	N	0,4	N	0,86	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11117	11117	A	T	MI.17075	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	358	120	I	F	Atc/Ttc	-2,24	0	0	probably_damaging	0,93	neutral	0,27	neutral	4,44	neutral	-0,86	deleterious	-3,09	medium_impact	1,96	neutral	0,67	neutral	0,44	deleterious	3,17	22,7	0,07	0,35	NA	NA	disease	0,79	disease	0,62	disease	0,57	1	neutral	0,94	neutral	0,17	deleterious	1	deleterious	0,62	low_impact	-1,77	medium_impact	-0,04	medium_impact	0,81	0,46	0,8	46,19	9,15	N	0,34	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11117	11117	A	G	MI.17076	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	358	120	I	V	Atc/Gtc	-2,24	0	0	benign	0,05	neutral	0,35	neutral	4,51	neutral	1,14	neutral	-0,58	low_impact	1,88	neutral	0,77	neutral	0,88	neutral	-0,49	0,23	0,22	0,45	NA	NA	neutral	0,18	neutral	0,37	neutral	0,22	6	neutral	0,62	deleterious	0,65	neutral	-6	neutral	0,11	medium_impact	0,48	medium_impact	0,05	medium_impact	0,73	0,49	0,8	46,19	9,15	N	0,41	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11118	11118	T	A	MI.17077	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	359	120	I	N	aTc/aAc	0,75	0,22	0	probably_damaging	0,96	deleterious	0	neutral	4,34	deleterious	-4,59	deleterious	-5,31	high_impact	4,12	neutral	0,68	neutral	0,44	deleterious	4,18	23,8	0,03	0,35	NA	NA	disease	0,86	disease	0,61	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-2,01	low_impact	-1,48	high_impact	2,95	0,31	0,8	46,19	9,15	N	0,43	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11118	11118	T	G	MI.17078	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	359	120	I	S	aTc/aGc	0,75	0,22	0	probably_damaging	0,9	deleterious	0	neutral	4,36	deleterious	-3,31	deleterious	-4,54	high_impact	3,77	neutral	0,72	neutral	0,46	deleterious	2,57	19,93	0,02	0,35	NA	NA	disease	0,85	disease	0,6	disease	0,74	5	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,53	low_impact	-1,61	low_impact	-1,48	high_impact	2,6	0,25	0,8	46,19	9,15	N	0,41	N	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11118	11118	T	C	MI.17079	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	359	120	I	T	aTc/aCc	0,75	0,22	0	possibly_damaging	0,75	deleterious	0	neutral	4,37	neutral	-2,76	deleterious	-3,67	medium_impact	3,43	neutral	0,76	neutral	0,56	neutral	1,5	13,3	0,03	0,35	NA	NA	disease	0,7	disease	0,54	disease	0,59	2	deleterious	1	neutral	0,13	deleterious	4	deleterious	0,43	low_impact	-1,17	low_impact	-1,48	high_impact	2,27	0,22	0,8	46,19	9,15	N	0,38	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8491	8491	A	T	MI.1708	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	126	42	M	I	atA/atT	-7,28	0	0	possibly_damaging	0,82	neutral	0,46	neutral	1,25	neutral	-2,15	neutral	-0,51	neutral_impact	-0,18	neutral	0,99	neutral	0,95	neutral	1,29	12,21	0,64626452	0,85	neutral	0,23	neutral	0,12	neutral	0,34	neutral	0,06	9	neutral	0,81	neutral	0,32	neutral	-3	deleterious	0,44	low_impact	-1,38	medium_impact	0,25	low_impact	-1,25	0,52	0,85	17,65	9,06	N	0,48	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11119	11119	C	G	MI.17080	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	360	120	I	M	atC/atG	4,67	0,76	0	probably_damaging	0,93	neutral	0,1	neutral	4,46	neutral	-2,38	neutral	-2,22	medium_impact	3,15	neutral	0,74	neutral	0,54	deleterious	2,99	22,2	0,08	0,35	NA	NA	disease	0,63	disease	0,53	disease	0,54	1	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,58	low_impact	-1,77	medium_impact	-0,33	medium_impact	1,99	0,38	0,8	46,19	9,15	N	0,49	N	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11119	11119	C	A	MI.17081	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	360	120	I	M	atC/atA	4,67	0,76	0	probably_damaging	0,93	neutral	0,1	neutral	4,46	neutral	-2,38	neutral	-2,22	medium_impact	3,15	neutral	0,74	neutral	0,54	deleterious	3,4	23	0,08	0,35	NA	NA	disease	0,63	disease	0,53	disease	0,54	1	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,58	low_impact	-1,77	medium_impact	-0,33	medium_impact	1,99	0,38	0,8	46,19	9,15	N	0,5	N	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11120	11120	T	G	MI.17082	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	361	121	F	V	Ttc/Gtc	-6,16	0	0	benign	0,05	deleterious	0,03	neutral	4,55	neutral	-2,96	neutral	0,62	medium_impact	2,78	neutral	0,76	neutral	0,69	deleterious	2,05	16,54	0,1	0,4	NA	NA	disease	0,66	neutral	0,5	disease	0,51	0	neutral	0,97	deleterious	0,49	deleterious	1	neutral	0,17	medium_impact	0,48	medium_impact	-0,64	medium_impact	1,62	0,29	0,8	46,62	10,39	N	0,43	N	0,17	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11120	11120	T	A	MI.17083	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	361	121	F	I	Ttc/Atc	-6,16	0	0	benign	0,03	neutral	0,06	neutral	4,53	deleterious	-3,36	neutral	1,08	medium_impact	2,44	neutral	0,74	neutral	0,6	deleterious	2,36	18,56	0,12	0,4	NA	NA	disease	0,56	neutral	0,48	neutral	0,5	0	neutral	0,94	deleterious	0,52	neutral	-3	neutral	0,17	medium_impact	0,7	medium_impact	-0,47	medium_impact	1,29	0,38	0,8	46,62	10,39	N	0,45	N	0,08	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11120	11120	T	C	MI.17084	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	361	121	F	L	Ttc/Ctc	-6,16	0	0	benign	0	neutral	0,48	neutral	4,58	neutral	-2,53	neutral	2,26	neutral_impact	-0,45	neutral	0,79	neutral	0,95	neutral	-0,28	0,74	0,13	0,4	NA	NA	neutral	0,35	neutral	0,34	neutral	0,14	7	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,11	high_impact	2,1	medium_impact	0,18	low_impact	-1,57	0,55	0,8	46,62	10,39	N	0,28	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11121	11121	T	C	MI.17085	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	362	121	F	S	tTc/tCc	-4,32	0	0	benign	0,01	neutral	0,19	neutral	4,61	deleterious	-3,33	neutral	-1,28	neutral_impact	0,42	neutral	0,7	neutral	0,85	deleterious	2,29	18,13	0,03	0,35	NA	NA	neutral	0,42	neutral	0,44	neutral	0,16	7	neutral	0,81	deleterious	0,59	neutral	-6	neutral	0,28	medium_impact	1,16	medium_impact	-0,15	medium_impact	-0,71	0,25	0,8	46,62	10,39	N	0,43	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11121	11121	T	A	MI.17086	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	362	121	F	Y	tTc/tAc	-4,32	0	0	benign	0,26	neutral	0,14	neutral	4,5	deleterious	-4,57	neutral	-0,79	low_impact	1,34	neutral	0,75	neutral	0,65	deleterious	2,33	18,33	0,16	0,45	NA	NA	neutral	0,5	disease	0,55	disease	0,66	3	neutral	0,83	neutral	0,44	neutral	-6	neutral	0,26	medium_impact	-0,29	medium_impact	-0,24	medium_impact	0,2	0,53	0,8	46,62	10,39	N	0,41	N	0,26	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11121	11121	T	G	MI.17087	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	362	121	F	C	tTc/tGc	-4,32	0	0	possibly_damaging	0,76	deleterious	0,04	neutral	4,47	deleterious	-4,55	neutral	-0,86	low_impact	1,63	neutral	0,71	neutral	0,46	deleterious	3,7	23,3	0,04	0,35	NA	NA	disease	0,71	disease	0,53	disease	0,63	3	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,59	low_impact	-1,19	medium_impact	-0,57	medium_impact	0,49	0,19	0,8	46,62	10,39	N	0,38	N	0,47	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11122	11122	C	A	MI.17088	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	363	121	F	L	ttC/ttA	2,14	0,48	0	benign	0	neutral	0,48	neutral	4,58	neutral	-2,53	neutral	2,26	neutral_impact	-0,45	neutral	0,79	neutral	0,95	deleterious	0,33	5,95	0,13	0,4	NA	NA	neutral	0,35	neutral	0,34	neutral	0,14	7	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,11	high_impact	2,1	medium_impact	0,18	low_impact	-1,57	0,55	0,8	46,62	10,39	N	0,31	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11122	11122	C	G	MI.17089	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	363	121	F	L	ttC/ttG	2,14	0,48	0	benign	0	neutral	0,48	neutral	4,58	neutral	-2,53	neutral	2,26	neutral_impact	-0,45	neutral	0,79	neutral	0,95	deleterious	0,03	2,84	0,13	0,4	NA	NA	neutral	0,35	neutral	0,34	neutral	0,14	7	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,11	high_impact	2,1	medium_impact	0,18	low_impact	-1,57	0,55	0,8	46,62	10,39	N	0,31	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8491	8491	A	C	MI.1709	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	126	42	M	I	atA/atC	-7,28	0	0	possibly_damaging	0,82	neutral	0,46	neutral	1,25	neutral	-2,15	neutral	-0,51	neutral_impact	-0,18	neutral	0,99	neutral	0,95	neutral	1,21	11,82	0,64626452	0,85	neutral	0,23	neutral	0,12	neutral	0,34	neutral	0,06	9	neutral	0,81	neutral	0,32	neutral	-3	deleterious	0,44	low_impact	-1,38	medium_impact	0,25	low_impact	-1,25	0,52	0,85	17,65	9,06	N	0,49	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11123	11123	T	C	MI.17090	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	364	122	F	L	Ttc/Ctc	0,29	0,47	0	probably_damaging	1	deleterious	0	neutral	4,71	neutral	-0,1	deleterious	-4,64	high_impact	4,42	neutral	0,61	damaging	0,16	deleterious	3,88	23,5	0,1	0,4	NA	NA	disease	0,82	disease	0,59	disease	0,7	4	deleterious	1	deleterious	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,25	0,48	0,8	45,97	8,86	N	0,47	N	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11123	11123	T	A	MI.17091	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	364	122	F	I	Ttc/Atc	0,29	0,47	0	probably_damaging	1	deleterious	0	neutral	4,64	neutral	-1,34	deleterious	-4,64	high_impact	4,42	neutral	0,63	damaging	0,18	deleterious	4,22	23,9	0,09	0,35	NA	NA	disease	0,83	disease	0,66	disease	0,73	5	deleterious	1	deleterious	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,25	0,33	0,8	45,97	8,86	N	0,48	N	0,96	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11123	11123	T	G	MI.17092	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	364	122	F	V	Ttc/Gtc	0,29	0,47	0	probably_damaging	1	deleterious	0	neutral	4,51	neutral	-1,59	deleterious	-5,41	high_impact	4,42	neutral	0,62	damaging	0,17	deleterious	3,92	23,5	0,08	0,35	NA	NA	disease	0,86	disease	0,69	disease	0,76	5	deleterious	1	deleterious	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,25	0,23	0,8	45,97	8,86	N	0,46	N	0,96	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11124	11124	T	A	MI.17093	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	365	122	F	Y	tTc/tAc	5,83	1	0	probably_damaging	1	neutral	0,1	neutral	4,51	neutral	-1,66	neutral	-2,32	medium_impact	2,77	neutral	0,63	damaging	0,17	deleterious	4,19	23,9	0,11	0,4	NA	NA	disease	0,77	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,33	medium_impact	1,61	0,54	0,8	45,97	8,86	P	0,63	P	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11124	11124	T	C	MI.17094	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	365	122	F	S	tTc/tCc	5,83	1	0	probably_damaging	1	deleterious	0	neutral	4,46	neutral	-2,81	deleterious	-6,18	high_impact	4,42	neutral	0,66	damaging	0,2	deleterious	4,18	23,8	0,04	0,35	NA	NA	disease	0,84	disease	0,66	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,25	0,27	0,8	45,97	8,86	P	0,59	P	0,93	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11124	11124	T	G	MI.17095	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	365	122	F	C	tTc/tGc	5,83	1	0	probably_damaging	1	deleterious	0	neutral	4,44	deleterious	-4,46	deleterious	-6,18	high_impact	4,42	neutral	0,64	damaging	0,15	deleterious	4,03	23,6	0,04	0,35	NA	NA	disease	0,84	disease	0,7	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	3,25	0,2	0,8	45,97	8,86	P	0,57	P	0,99	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11125	11125	C	A	MI.17096	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	366	122	F	L	ttC/ttA	5,83	1	0	probably_damaging	1	deleterious	0	neutral	4,71	neutral	-0,1	deleterious	-4,64	high_impact	4,42	neutral	0,61	damaging	0,16	deleterious	4,52	24,3	0,1	0,4	NA	NA	disease	0,82	disease	0,59	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,25	0,48	0,8	45,97	8,86	P	0,6	P	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11125	11125	C	G	MI.17097	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	366	122	F	L	ttC/ttG	5,83	1	0	probably_damaging	1	deleterious	0	neutral	4,71	neutral	-0,1	deleterious	-4,64	high_impact	4,42	neutral	0,61	damaging	0,16	deleterious	4,24	23,9	0,1	0,4	NA	NA	disease	0,82	disease	0,59	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,25	0,48	0,8	45,97	8,86	P	0,6	P	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11126	11126	G	A	MI.17098	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	367	123	E	K	Gaa/Aaa	-2,24	0	0	probably_damaging	1	deleterious	0	neutral	3,14	deleterious	-6,47	deleterious	-3,1	high_impact	4,5	damaging	0,34	damaging	0,06	deleterious	4,41	24,1	0,03	0,35	NA	NA	disease	0,88	disease	0,84	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,67	0,85	47,06	9,35	P	0,63	P	1	polymorphism	1	0,43	.	.	.	.	.	papillary thyroid carcinoma	.	.	.	.	.	.	.	.	.
chrM	11126	11126	G	C	MI.17099	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	367	123	E	Q	Gaa/Caa	-2,24	0	0	probably_damaging	1	deleterious	0	neutral	3,14	deleterious	-6,46	neutral	-2,32	high_impact	4,5	damaging	0,36	damaging	0,08	deleterious	3,24	22,8	0,06	0,35	NA	NA	disease	0,73	disease	0,78	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,36	0,8	47,06	9,35	P	0,6	P	0,92	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8605	8605	C	A	MI.171	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	79	27	P	T	Ccc/Acc	-6,58	0	0	probably_damaging	1	neutral	0,43	neutral	4,41	neutral	0,3	deleterious	-7,04	medium_impact	2,54	neutral	0,72	neutral	0,52	deleterious	3,48	23,1	0,32	0,65	neutral	0,49	disease	0,69	neutral	0,45	disease	0,51	0	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,22	medium_impact	1,08	0,51	0,9	48,23	8,81	N	0,28	N	0,94	polymorphism	0,76	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8492	8492	A	C	MI.1710	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	127	43	K	Q	Aaa/Caa	-3,57	0	0	probably_damaging	0,99	neutral	0,48	neutral	1,54	neutral	-0,88	neutral	-2,48	medium_impact	2,61	neutral	0,98	neutral	0,51	deleterious	3,37	22,9	0,68836831	0,85	neutral	0,4	neutral	0,24	neutral	0,45	neutral	0,1	8	deleterious	0,99	neutral	0,25	deleterious	1	deleterious	0,69	low_impact	-2,65	medium_impact	0,27	medium_impact	1,14	0,66	0,85	4,41	8,93	N	0,44	N	0,62	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11127	11127	A	T	MI.17100	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	368	123	E	V	gAa/gTa	6,06	1	0	probably_damaging	1	deleterious	0	neutral	3,12	deleterious	-8,28	deleterious	-5,42	high_impact	4,5	damaging	0,35	damaging	0,09	deleterious	4,2	23,9	0,02	0,35	NA	NA	disease	0,88	disease	0,78	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,13	0,8	47,06	9,35	P	0,73	P	0,8	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11127	11127	A	C	MI.17101	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	368	123	E	A	gAa/gCa	6,06	1	0	probably_damaging	1	deleterious	0	neutral	3,14	deleterious	-6,58	deleterious	-4,64	high_impact	4,14	damaging	0,4	damaging	0,14	deleterious	3,67	23,2	0,03	0,35	NA	NA	disease	0,69	disease	0,77	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,97	0,21	0,8	47,06	9,35	P	0,78	P	0,74	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11127	11127	A	G	MI.17102	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	368	123	E	G	gAa/gGa	6,06	1	0	probably_damaging	1	deleterious	0	neutral	3,18	deleterious	-5,24	deleterious	-5,42	high_impact	4,5	damaging	0,36	damaging	0,13	deleterious	4,22	23,9	0,03	0,35	NA	NA	disease	0,81	disease	0,77	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,08	0,8	47,06	9,35	P	0,8	P	0,53	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11128	11128	A	C	MI.17103	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	369	123	E	D	gaA/gaC	8,59	1	0	probably_damaging	1	deleterious	0	neutral	3,28	deleterious	-3,93	neutral	-2,32	high_impact	3,94	damaging	0,34	damaging	0,08	deleterious	3,62	23,2	0,07	0,35	NA	NA	disease	0,73	disease	0,78	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	2,77	0,31	0,8	47,06	9,35	P	0,79	P	0,89	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11128	11128	A	T	MI.17104	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	369	123	E	D	gaA/gaT	8,59	1	0	probably_damaging	1	deleterious	0	neutral	3,28	deleterious	-3,93	neutral	-2,32	high_impact	3,94	damaging	0,34	damaging	0,08	deleterious	3,71	23,3	0,07	0,35	NA	NA	disease	0,73	disease	0,78	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	2,77	0,31	0,8	47,06	9,35	P	0,79	P	0,89	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11129	11129	A	G	MI.17105	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	370	124	T	A	Acc/Gcc	2,83	1	0	benign	0,02	neutral	1	neutral	4,7	neutral	1,22	neutral	1,01	neutral_impact	-0,92	neutral	0,72	neutral	0,99	neutral	-1,37	0	0,26	0,45	NA	NA	neutral	0,07	neutral	0,17	neutral	0,23	5	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,09	medium_impact	0,87	high_impact	1,88	low_impact	-2,04	0,28	0,8	25,71	24,71	N	0,47	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11129	11129	A	C	MI.17106	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	370	124	T	P	Acc/Ccc	2,83	1	0	possibly_damaging	0,8	deleterious	0,02	neutral	4,58	neutral	-2,7	neutral	-1,86	medium_impact	2,69	neutral	0,66	neutral	0,46	neutral	1,66	14,18	0,04	0,35	NA	NA	disease	0,91	disease	0,65	disease	0,82	6	deleterious	0,99	neutral	0,11	deleterious	4	deleterious	0,56	low_impact	-1,28	medium_impact	-0,75	medium_impact	1,54	0,39	0,8	25,71	24,71	P	0,51	P	0,93	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11129	11129	A	T	MI.17107	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	370	124	T	S	Acc/Tcc	2,83	1	0	benign	0,35	neutral	0,5	neutral	4,63	neutral	-0,58	neutral	-0,19	neutral_impact	0,42	neutral	0,66	neutral	0,98	neutral	1,18	11,67	0,34	0,5	NA	NA	neutral	0,42	neutral	0,21	neutral	0,18	7	neutral	0,42	deleterious	0,58	neutral	-6	neutral	0,21	medium_impact	-0,47	medium_impact	0,2	medium_impact	-0,71	0,63	0,8	25,71	24,71	P	0,56	P	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11130	11130	C	G	MI.17108	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	371	124	T	S	aCc/aGc	0,29	0,98	0	benign	0,35	neutral	0,5	neutral	4,63	neutral	-0,58	neutral	-0,19	neutral_impact	0,42	neutral	0,66	neutral	0,98	neutral	1,5	13,33	0,34	0,5	NA	NA	neutral	0,42	neutral	0,21	neutral	0,18	7	neutral	0,42	deleterious	0,58	neutral	-6	neutral	0,21	medium_impact	-0,47	medium_impact	0,2	medium_impact	-0,71	0,63	0,8	25,71	24,71	P	0,52	P	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11130	11130	C	A	MI.17109	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	371	124	T	N	aCc/aAc	0,29	0,98	0	possibly_damaging	0,74	deleterious	0,03	neutral	4,59	neutral	-2,59	neutral	-2,08	medium_impact	2,34	neutral	0,69	neutral	0,62	deleterious	1,96	15,93	0,26	0,45	NA	NA	disease	0,82	disease	0,51	disease	0,73	5	neutral	0,98	neutral	0,15	deleterious	4	deleterious	0,43	low_impact	-1,14	medium_impact	-0,64	medium_impact	1,19	0,52	0,8	25,71	24,71	N	0,5	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8492	8492	A	G	MI.1711	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	127	43	K	E	Aaa/Gaa	-3,57	0	0	probably_damaging	0,97	neutral	0,84	neutral	1,55	neutral	-0,63	neutral	-2,45	low_impact	1,75	neutral	0,99	neutral	0,69	deleterious	2,92	21,9	0,42878708	0,85	neutral	0,35	neutral	0,24	neutral	0,43	neutral	0,1	8	neutral	0,97	neutral	0,44	neutral	-2	deleterious	0,71	low_impact	-2,19	medium_impact	0,7	medium_impact	0,4	0,52	0,85	4,41	8,93	N	0,35	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11130	11130	C	T	MI.17110	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	371	124	T	I	aCc/aTc	0,29	0,98	0	possibly_damaging	0,6	neutral	0,18	neutral	4,68	neutral	1,41	neutral	-1,88	low_impact	0,96	neutral	0,73	neutral	0,73	deleterious	1,97	16,01	0,11	0,4	NA	NA	disease	0,81	disease	0,52	disease	0,57	1	neutral	0,82	neutral	0,29	neutral	-3	neutral	0,36	medium_impact	-0,88	medium_impact	-0,17	medium_impact	-0,18	0,57	0,8	25,71	24,71	N	0,49	N	0,77	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11132	11132	A	G	MI.17111	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	373	125	T	A	Aca/Gca	-10,55	0	0	probably_damaging	1	deleterious	0,01	neutral	4,63	neutral	-0,86	deleterious	-3,87	medium_impact	2,36	neutral	0,68	neutral	0,58	deleterious	3,42	23	0,26	0,45	NA	NA	disease	0,62	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,21	0,33	0,8	47,93	9,47	N	0,4	N	0,69	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11132	11132	A	C	MI.17112	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	373	125	T	P	Aca/Cca	-10,55	0	0	probably_damaging	1	deleterious	0	neutral	4,57	deleterious	-4,31	deleterious	-4,64	medium_impact	3,37	neutral	0,7	neutral	0,5	deleterious	3,41	23	0,04	0,35	NA	NA	disease	0,87	disease	0,76	disease	0,8	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	2,21	0,36	0,8	47,93	9,47	N	0,4	N	0,97	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11132	11132	A	T	MI.17113	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	373	125	T	S	Aca/Tca	-10,55	0	0	probably_damaging	1	neutral	1	neutral	4,66	neutral	-1,33	deleterious	-3,09	low_impact	0,96	neutral	0,65	neutral	0,72	deleterious	3,29	22,8	0,36	0,5	NA	NA	neutral	0,35	neutral	0,35	neutral	0,16	7	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,76	low_impact	-3,54	high_impact	1,88	medium_impact	-0,18	0,62	0,8	47,93	9,47	N	0,33	N	0,87	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11133	11133	C	A	MI.17114	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	374	125	T	K	aCa/aAa	6,75	1	0	probably_damaging	1	deleterious	0	neutral	4,6	deleterious	-3,53	deleterious	-4,64	medium_impact	3,37	neutral	0,67	neutral	0,41	deleterious	4,35	24,1	0,07	0,35	NA	NA	disease	0,89	disease	0,76	disease	0,81	6	deleterious	1	deleterious	0	deleterious	5	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	2,21	0,34	0,8	47,93	9,47	P	0,56	P	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11133	11133	C	T	MI.17115	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	374	125	T	M	aCa/aTa	6,75	1	0	probably_damaging	1	deleterious	0	neutral	4,61	neutral	0,51	deleterious	-4,64	medium_impact	2,1	neutral	0,68	neutral	0,56	deleterious	3,97	23,6	0,14	0,4	NA	NA	disease	0,81	disease	0,66	disease	0,71	4	deleterious	1	deleterious	0	deleterious	5	deleterious	0,8	low_impact	-3,54	low_impact	-1,48	medium_impact	0,95	0,46	0,8	47,93	9,47	P	0,54	P	0,92	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11135	11135	C	G	MI.17116	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	376	126	L	V	Ctt/Gtt	-10,32	0	0	probably_damaging	1	deleterious	0,01	neutral	4,46	neutral	-2,53	neutral	-2,32	medium_impact	3,1	damaging	0,55	damaging	0,15	deleterious	3,41	23	0,26	0,45	NA	NA	disease	0,64	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,82	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,94	0,45	0,8	46,62	9,31	N	0,3	N	0,89	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11135	11135	C	T	MI.17117	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	376	126	L	F	Ctt/Ttt	-10,32	0	0	probably_damaging	1	deleterious	0	neutral	4,42	deleterious	-4,1	deleterious	-3,09	high_impact	3,87	damaging	0,53	damaging	0,13	deleterious	3,89	23,5	0,12	0,4	NA	NA	disease	0,72	disease	0,67	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	2,7	0,38	0,8	46,62	9,31	N	0,33	N	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11135	11135	C	A	MI.17118	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	376	126	L	I	Ctt/Att	-10,32	0	0	probably_damaging	1	neutral	0,08	neutral	4,45	neutral	-2,86	neutral	-1,55	medium_impact	2,73	damaging	0,55	damaging	0,17	deleterious	4,08	23,7	0,26	0,45	NA	NA	disease	0,65	neutral	0,5	disease	0,51	0	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	-0,39	medium_impact	1,58	0,45	0,8	46,62	9,31	N	0,35	N	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11136	11136	T	A	MI.17119	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	377	126	L	H	cTt/cAt	-0,4	0	0	probably_damaging	1	deleterious	0	neutral	4,42	deleterious	-5,11	deleterious	-5,42	high_impact	4,42	damaging	0,53	damaging	0,12	deleterious	4,14	23,8	0,04	0,35	NA	NA	disease	0,79	disease	0,74	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,25	0,13	0,8	46,62	9,31	N	0,45	N	0,96	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8493	8493	A	T	MI.1712	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	128	43	K	M	aAa/aTa	-0,8	0	0	probably_damaging	1	neutral	0,11	neutral	1,5	neutral	-2,39	deleterious	-3,86	low_impact	1,72	neutral	0,99	neutral	0,78	deleterious	3,71	23,3	0,42878708	0,85	disease	0,68	neutral	0,15	neutral	0,39	neutral	0,11	8	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,72	low_impact	-3,6	medium_impact	-0,22	medium_impact	0,38	0,47	0,85	4,41	8,93	P	0,59	P	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11136	11136	T	G	MI.17120	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	377	126	L	R	cTt/cGt	-0,4	0	0	probably_damaging	1	deleterious	0	neutral	4,44	deleterious	-4,35	deleterious	-4,64	high_impact	4,42	damaging	0,56	damaging	0,12	deleterious	4,09	23,7	0,02	0,35	NA	NA	disease	0,89	disease	0,77	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,54	low_impact	-1,48	high_impact	3,25	0,09	0,8	46,62	9,31	N	0,54	P	1	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11136	11136	T	C	MI.17121	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	377	126	L	P	cTt/cCt	-0,4	0	0	probably_damaging	1	deleterious	0	neutral	4,42	deleterious	-4,69	deleterious	-5,42	high_impact	3,87	damaging	0,53	damaging	0,13	deleterious	3,86	23,5	0,02	0,35	NA	NA	disease	0,78	disease	0,72	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	2,7	0,08	0,8	46,62	9,31	N	0,37	N	0,98	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11138	11138	A	G	MI.17122	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	379	127	I	V	Atc/Gtc	-4,09	0	0	benign	0,08	neutral	0,1	neutral	4,61	neutral	-1,02	neutral	-0,62	low_impact	1,32	neutral	0,81	neutral	0,98	neutral	1,76	14,78	0,44	0,55	NA	NA	neutral	0,36	neutral	0,37	neutral	0,16	7	neutral	0,89	deleterious	0,51	neutral	-6	deleterious	0,66	medium_impact	0,28	medium_impact	-0,33	medium_impact	0,18	0,46	0,8	15,25	12,4	N	0,45	N	0,16	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11138	11138	A	C	MI.17123	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	379	127	I	L	Atc/Ctc	-4,09	0	0	possibly_damaging	0,52	neutral	0,25	neutral	4,84	neutral	0,58	neutral	-1,45	low_impact	1,51	neutral	0,77	neutral	0,89	deleterious	3,68	23,3	0,24	0,45	NA	NA	disease	0,69	neutral	0,31	neutral	0,48	1	neutral	0,73	neutral	0,37	neutral	-3	deleterious	0,71	medium_impact	-0,75	medium_impact	-0,07	medium_impact	0,37	0,59	0,8	15,25	12,4	N	0,39	N	0,64	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11138	11138	A	T	MI.17124	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	379	127	I	F	Atc/Ttc	-4,09	0	0	probably_damaging	0,96	neutral	0,14	neutral	4,54	neutral	-2,59	deleterious	-3,04	medium_impact	2,67	neutral	0,65	neutral	0,51	deleterious	3,73	23,3	0,09	0,4	NA	NA	disease	0,86	disease	0,67	disease	0,75	5	neutral	0,98	neutral	0,09	deleterious	1	deleterious	0,82	low_impact	-2,01	medium_impact	-0,24	medium_impact	1,52	0,42	0,8	15,25	12,4	N	0,37	N	0,94	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11139	11139	T	A	MI.17125	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	380	127	I	N	aTc/aAc	3,06	0,99	0	probably_damaging	0,98	deleterious	0	neutral	4,44	deleterious	-5,13	deleterious	-5,29	high_impact	4,08	neutral	0,64	neutral	0,49	deleterious	4,31	24	0,07	0,35	NA	NA	disease	0,89	disease	0,67	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,31	low_impact	-1,48	high_impact	2,91	0,17	0,8	15,25	12,4	P	0,53	P	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11139	11139	T	G	MI.17126	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	380	127	I	S	aTc/aGc	3,06	0,99	0	probably_damaging	0,94	deleterious	0,01	neutral	4,47	deleterious	-3,61	deleterious	-4,51	high_impact	4,08	neutral	0,64	neutral	0,55	deleterious	4,15	23,8	0,04	0,35	NA	NA	disease	0,87	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,84	low_impact	-1,84	medium_impact	-0,92	high_impact	2,91	0,11	0,8	15,25	12,4	P	0,56	P	0,93	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11139	11139	T	C	MI.17127	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	380	127	I	T	aTc/aCc	3,06	0,99	0	possibly_damaging	0,83	deleterious	0	neutral	4,52	deleterious	-3,33	deleterious	-3,67	high_impact	3,54	neutral	0,62	neutral	0,46	deleterious	3,32	22,9	0,08	0,35	NA	NA	disease	0,76	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,09	deleterious	5	deleterious	0,8	low_impact	-1,37	low_impact	-1,48	high_impact	2,38	0,15	0,8	15,25	12,4	P	0,55	P	0,96	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11140	11140	C	G	MI.17128	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	381	127	I	M	atC/atG	4,67	0,99	0	probably_damaging	0,96	deleterious	0,01	neutral	4,51	neutral	-2,89	neutral	-2,17	medium_impact	3,19	neutral	0,72	neutral	0,78	deleterious	3,34	22,9	0,13	0,4	NA	NA	disease	0,7	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,75	low_impact	-2,01	medium_impact	-0,92	high_impact	2,03	0,46	0,8	15,25	12,4	P	0,57	P	0,69	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11140	11140	C	A	MI.17129	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	381	127	I	M	atC/atA	4,67	0,99	0	probably_damaging	0,96	deleterious	0,01	neutral	4,51	neutral	-2,89	neutral	-2,17	medium_impact	3,19	neutral	0,72	neutral	0,78	deleterious	3,78	23,4	0,13	0,4	NA	NA	disease	0,7	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,75	low_impact	-2,01	medium_impact	-0,92	high_impact	2,03	0,46	0,8	15,25	12,4	P	0,57	P	0,69	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8493	8493	A	C	MI.1713	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	128	43	K	T	aAa/aCa	-0,8	0	0	probably_damaging	0,98	neutral	0,53	neutral	2,01	neutral	2,54	deleterious	-3,11	low_impact	1,27	neutral	1	neutral	0,93	deleterious	2,22	17,61	0,47385093	0,85	neutral	0,27	neutral	0,2	neutral	0,34	neutral	0,08	8	deleterious	0,98	neutral	0,28	neutral	-2	deleterious	0,68	low_impact	-2,36	medium_impact	0,32	medium_impact	-0,01	0,5	0,85	4,41	8,93	N	0,42	N	0,1	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11141	11141	C	A	MI.17130	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	382	128	P	T	Ccc/Acc	-2,24	0	0	probably_damaging	1	deleterious	0	neutral	4,57	neutral	-2,06	deleterious	-6,19	high_impact	4,47	damaging	0,54	damaging	0,08	deleterious	3,62	23,2	0,11	0,4	NA	NA	disease	0,82	disease	0,71	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,3	0,49	0,8	47,06	9,38	N	0,4	N	0,89	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11141	11141	C	G	MI.17131	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	382	128	P	A	Ccc/Gcc	-2,24	0	0	probably_damaging	1	deleterious	0	neutral	4,58	neutral	0,2	deleterious	-6,19	high_impact	4,47	damaging	0,51	damaging	0,11	deleterious	3,04	22,4	0,14	0,4	NA	NA	disease	0,72	disease	0,69	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	3,3	0,68	0,85	47,06	9,38	N	0,44	N	0,77	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11141	11141	C	T	MI.17132	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	382	128	P	S	Ccc/Tcc	-2,24	0	0	probably_damaging	1	deleterious	0	neutral	4,6	neutral	-0,27	deleterious	-6,19	high_impact	4,13	damaging	0,51	damaging	0,1	deleterious	3,83	23,4	0,17	0,45	NA	NA	disease	0,84	disease	0,69	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	2,96	0,13	0,8	47,06	9,38	N	0,39	N	0,71	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11142	11142	C	T	MI.17133	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	383	128	P	L	cCc/cTc	4,44	0,99	0	probably_damaging	1	deleterious	0,04	neutral	4,63	neutral	-1,82	deleterious	-7,74	medium_impact	3,27	damaging	0,51	damaging	0,07	deleterious	4,36	24,1	0,09	0,35	NA	NA	disease	0,91	disease	0,69	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,87	low_impact	-3,54	medium_impact	-0,57	high_impact	2,11	0,62	0,8	47,06	9,38	P	0,53	P	0,97	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11142	11142	C	G	MI.17134	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	383	128	P	R	cCc/cGc	4,44	0,99	0	probably_damaging	1	deleterious	0	neutral	4,49	deleterious	-4,08	deleterious	-6,96	high_impact	4,47	damaging	0,59	damaging	0,08	deleterious	3,53	23,1	0,05	0,35	NA	NA	disease	0,92	disease	0,81	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,3	0,33	0,8	47,06	9,38	P	0,64	P	0,58	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11142	11142	C	A	MI.17135	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	383	128	P	H	cCc/cAc	4,44	0,99	0	probably_damaging	1	deleterious	0	neutral	4,48	deleterious	-4,72	deleterious	-6,96	high_impact	4,47	damaging	0,54	damaging	0,07	deleterious	3,98	23,6	0,08	0,35	NA	NA	disease	0,87	disease	0,8	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	3,3	0,27	0,8	47,06	9,38	P	0,63	P	0,7	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11144	11144	A	C	MI.17136	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	385	129	T	P	Acc/Ccc	-12,62	0	0	probably_damaging	1	deleterious	0	neutral	4,51	deleterious	-3,52	deleterious	-4,63	high_impact	4,1	neutral	0,65	neutral	0,48	deleterious	3,97	23,6	0,03	0,35	NA	NA	disease	0,85	disease	0,74	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	2,93	0,33	0,8	47,06	9,2	N	0,43	N	0,97	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11144	11144	A	T	MI.17137	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	385	129	T	S	Acc/Tcc	-12,62	0	0	probably_damaging	1	deleterious	0	neutral	4,84	neutral	2,24	deleterious	-3,08	high_impact	3,55	damaging	0,59	neutral	0,61	deleterious	3,8	23,4	0,36	0,5	NA	NA	disease	0,75	disease	0,63	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	2,39	0,68	0,85	47,06	9,2	N	0,46	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11144	11144	A	G	MI.17138	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	385	129	T	A	Acc/Gcc	-12,62	0	0	probably_damaging	1	deleterious	0,01	neutral	4,61	neutral	-0,47	deleterious	-3,86	medium_impact	2,86	damaging	0,59	neutral	0,75	deleterious	3,97	23,6	0,21	0,45	NA	NA	disease	0,69	disease	0,54	disease	0,61	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,81	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,7	0,31	0,8	47,06	9,2	N	0,41	N	0,69	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11145	11145	C	A	MI.17139	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	386	129	T	N	aCc/aAc	6,75	1	0	probably_damaging	1	deleterious	0	neutral	4,52	deleterious	-3,3	deleterious	-3,86	high_impact	4,1	neutral	0,6	neutral	0,52	deleterious	3,64	23,2	0,19	0,45	NA	NA	disease	0,85	disease	0,65	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,93	0,59	0,8	47,06	9,2	P	0,6	P	0,93	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8494	8494	A	C	MI.1714	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	129	43	K	N	aaA/aaC	0,13	0	0	probably_damaging	0,99	neutral	0,44	neutral	1,53	neutral	-1,12	neutral	-2,44	low_impact	1,55	neutral	1	neutral	0,84	neutral	1,69	14,34	0,76472473	0,85	neutral	0,45	neutral	0,08	neutral	0,36	neutral	0,04	9	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,68	low_impact	-2,65	medium_impact	0,23	medium_impact	0,23	0,66	0,85	4,41	8,93	N	0,47	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11145	11145	C	G	MI.17140	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	386	129	T	S	aCc/aGc	6,75	1	0	probably_damaging	1	deleterious	0	neutral	4,84	neutral	2,24	deleterious	-3,08	high_impact	3,55	damaging	0,59	neutral	0,61	deleterious	3,46	23	0,36	0,5	NA	NA	disease	0,75	disease	0,63	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	2,39	0,68	0,85	47,06	9,2	P	0,61	P	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11145	11145	C	T	MI.17141	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	386	129	T	I	aCc/aTc	6,75	1	0	probably_damaging	1	neutral	0,31	neutral	4,62	neutral	-1,02	deleterious	-4,64	low_impact	1,84	neutral	0,61	neutral	0,61	deleterious	3,95	23,6	0,1	0,4	NA	NA	disease	0,87	disease	0,53	disease	0,67	3	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,86	low_impact	-3,54	medium_impact	0,01	medium_impact	0,69	0,54	0,8	47,06	9,2	P	0,56	P	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11147	11147	T	A	MI.17142	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	388	130	L	M	Ttg/Atg	-11,01	0	0	probably_damaging	1	neutral	0,06	neutral	4,37	neutral	-2,07	neutral	-1,5	low_impact	1,8	neutral	0,71	neutral	0,72	deleterious	3,51	23,1	0,26	0,45	NA	NA	neutral	0,45	neutral	0,21	neutral	0,24	5	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	-0,47	medium_impact	0,66	0,64	0,8	45,53	8,78	N	0,47	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11147	11147	T	G	MI.17143	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	388	130	L	V	Ttg/Gtg	-11,01	0	0	probably_damaging	1	deleterious	0,04	neutral	4,47	neutral	-0,42	neutral	-2,3	medium_impact	2,53	neutral	0,61	damaging	0,13	deleterious	3,36	22,9	0,23	0,45	NA	NA	disease	0,6	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,38	0,61	0,8	45,53	8,78	N	0,32	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11148	11148	T	G	MI.17144	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	389	130	L	W	tTg/tGg	-0,17	0	0	probably_damaging	1	deleterious	0	neutral	4,34	neutral	-2,29	deleterious	-4,62	medium_impact	3,31	neutral	0,63	damaging	0,13	deleterious	3,71	23,3	0,04	0,35	NA	NA	disease	0,76	disease	0,6	disease	0,67	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,15	0,2	0,8	45,53	8,78	N	0,32	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11148	11148	T	C	MI.17145	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	389	130	L	S	tTg/tCg	-0,17	0	0	probably_damaging	1	deleterious	0,01	neutral	4,36	neutral	-2,05	deleterious	-4,62	medium_impact	3,45	neutral	0,63	damaging	0,14	deleterious	3,7	23,3	0,04	0,35	NA	NA	disease	0,76	disease	0,59	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,85	low_impact	-3,54	medium_impact	-0,92	high_impact	2,29	0,28	0,8	45,53	8,78	N	0,33	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11149	11149	G	T	MI.17146	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	390	130	L	F	ttG/ttT	7,44	0,95	0,02	probably_damaging	1	neutral	0,19	neutral	4,61	neutral	0,84	deleterious	-3,08	low_impact	1,47	neutral	0,61	damaging	0,14	deleterious	3,55	23,1	0,21	0,45	NA	NA	disease	0,69	neutral	0,44	disease	0,51	0	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,15	medium_impact	0,33	0,57	0,8	45,53	8,78	P	0,5	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11149	11149	G	C	MI.17147	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	390	130	L	F	ttG/ttC	7,44	0,95	0,02	probably_damaging	1	neutral	0,19	neutral	4,61	neutral	0,84	deleterious	-3,08	low_impact	1,47	neutral	0,61	damaging	0,14	deleterious	3,36	22,9	0,21	0,45	NA	NA	disease	0,69	neutral	0,44	disease	0,51	0	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,82	low_impact	-3,54	medium_impact	-0,15	medium_impact	0,33	0,57	0,8	45,53	8,78	P	0,5	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11150	11150	G	T	MI.17148	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	391	131	A	S	Gct/Tct	-6,16	0	0	benign	0,12	deleterious	0,01	neutral	4,6	neutral	-2,14	neutral	-0,85	low_impact	0,85	neutral	0,76	neutral	0,67	neutral	1,74	14,65	0,23	0,45	NA	NA	neutral	0,37	neutral	0,41	neutral	0,15	7	deleterious	0,99	neutral	0,45	neutral	-2	neutral	0,22	medium_impact	0,1	medium_impact	-0,92	medium_impact	-0,29	0,41	0,8	27,45	8,14	N	0,41	N	0,37	polymorphism	1	0,03	rs386829118	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11150	11150	G	C	MI.17149	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	391	131	A	P	Gct/Cct	-6,16	0	0	benign	0,34	deleterious	0	neutral	4,59	neutral	-1,75	neutral	-1,6	low_impact	1,54	neutral	0,68	neutral	0,46	deleterious	2	16,18	0,06	0,35	NA	NA	disease	0,78	disease	0,57	disease	0,74	5	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,52	medium_impact	-0,45	low_impact	-1,48	medium_impact	0,4	0,51	0,8	27,45	8,14	N	0,34	N	0,6	polymorphism	1	0,03	rs386829118	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8494	8494	A	T	MI.1715	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	129	43	K	N	aaA/aaT	0,13	0	0	probably_damaging	0,99	neutral	0,44	neutral	1,53	neutral	-1,12	neutral	-2,44	low_impact	1,55	neutral	1	neutral	0,84	neutral	1,75	14,67	0,76472473	0,85	neutral	0,45	neutral	0,08	neutral	0,36	neutral	0,04	9	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,68	low_impact	-2,65	medium_impact	0,23	medium_impact	0,23	0,66	0,85	4,41	8,93	N	0,49	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11150	11150	G	A	MI.17150	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	391	131	A	T	Gct/Act	-6,16	0	0	benign	0,06	deleterious	0	neutral	4,61	neutral	-1,86	neutral	-0,09	low_impact	1,2	neutral	0,77	neutral	0,67	deleterious	2,23	17,74	0,17	0,45	NA	NA	neutral	0,32	neutral	0,45	neutral	0,15	7	deleterious	1	deleterious	0,47	neutral	-2	neutral	0,16	medium_impact	0,41	low_impact	-1,48	medium_impact	0,06	0,63	0,8	27,45	8,14	N	0,45	N	0,3	polymorphism	1	0,01	rs386829118	.	.	.	.	head/neck tumor	.	.	.	.	.	.	.	.	.
chrM	11151	11151	C	A	MI.17151	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	392	131	A	D	gCt/gAt	0,06	0	0,03	benign	0,34	deleterious	0	neutral	4,56	deleterious	-4,67	neutral	-1,69	low_impact	1,54	neutral	0,73	neutral	0,53	deleterious	2,52	19,6	0,02	0,35	NA	NA	disease	0,67	disease	0,56	disease	0,65	3	deleterious	1	neutral	0,33	neutral	-2	neutral	0,36	medium_impact	-0,45	low_impact	-1,48	medium_impact	0,4	0,34	0,8	27,45	8,14	N	0,38	N	0,6	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11151	11151	C	T	MI.17152	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	392	131	A	V	gCt/gTt	0,06	0	0,03	benign	0	neutral	0,35	neutral	4,72	neutral	-0,33	neutral	2,84	neutral_impact	-0,72	neutral	0,76	neutral	0,99	neutral	1,24	11,96	0,16	0,45	NA	NA	neutral	0,28	neutral	0,19	neutral	0,16	7	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,05	low_impact	-1,84	0,73	0,85	27,45	8,14	N	0,44	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11151	11151	C	G	MI.17153	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	392	131	A	G	gCt/gGt	0,06	0	0,03	benign	0,12	deleterious	0	neutral	4,6	neutral	-0,94	neutral	-2,31	neutral_impact	0,74	neutral	0,76	neutral	0,66	deleterious	2,03	16,38	0,18	0,45	NA	NA	neutral	0,39	neutral	0,38	neutral	0,15	7	deleterious	1	neutral	0,44	neutral	-2	neutral	0,23	medium_impact	0,1	low_impact	-1,48	medium_impact	-0,39	0,6	0,8	27,45	8,14	N	0,39	N	0,6	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11153	11153	A	C	MI.17154	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	394	132	I	L	Atc/Ctc	-8,01	0	0	probably_damaging	1	neutral	1	neutral	5,28	neutral	3,59	neutral	-1,37	neutral_impact	-0,2	neutral	0,75	neutral	0,77	deleterious	2,53	19,64	0,18	0,45	NA	NA	neutral	0,11	disease	0,58	neutral	0,24	5	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,6	low_impact	-3,54	high_impact	1,88	low_impact	-1,32	0,37	0,8	10,46	9,27	N	0,36	N	0,86	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11153	11153	A	T	MI.17155	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	394	132	I	F	Atc/Ttc	-8,01	0	0	probably_damaging	1	deleterious	0,01	neutral	4,55	neutral	-1,75	deleterious	-3	medium_impact	2,58	neutral	0,74	damaging	0,14	deleterious	3,83	23,4	0,04	0,35	NA	NA	disease	0,66	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,76	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,43	0,37	0,8	10,46	9,27	N	0,34	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11153	11153	A	G	MI.17156	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	394	132	I	V	Atc/Gtc	-8,01	0	0	probably_damaging	1	deleterious	0,03	neutral	4,66	neutral	-0,54	neutral	-0,66	medium_impact	2,17	neutral	0,79	neutral	0,77	deleterious	1,87	15,43	0,25	0,45	NA	NA	neutral	0,25	disease	0,6	neutral	0,36	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,62	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,02	0,48	0,8	10,46	9,27	N	0,41	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11154	11154	T	A	MI.17157	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	395	132	I	N	aTc/aAc	0,52	0,07	0	probably_damaging	1	deleterious	0	neutral	4,53	deleterious	-3,7	deleterious	-5,27	high_impact	3,62	neutral	0,74	damaging	0,15	deleterious	4,32	24	0,02	0,35	NA	NA	disease	0,79	disease	0,78	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	2,46	0,1	0,8	10,46	9,27	N	0,46	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11154	11154	T	G	MI.17158	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	395	132	I	S	aTc/aGc	0,52	0,07	0	probably_damaging	1	deleterious	0	neutral	4,58	neutral	-2,4	deleterious	-4,49	medium_impact	3,27	neutral	0,75	damaging	0,15	deleterious	4,21	23,9	0,01	0,35	NA	NA	disease	0,76	disease	0,75	disease	0,77	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	2,11	0,11	0,8	10,46	9,27	N	0,4	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11154	11154	T	C	MI.17159	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	395	132	I	T	aTc/aCc	0,52	0,07	0	probably_damaging	1	deleterious	0	neutral	4,56	neutral	-2,03	deleterious	-3,66	medium_impact	3,27	neutral	0,84	damaging	0,12	deleterious	3,35	22,9	0,02	0,35	NA	NA	disease	0,62	disease	0,76	disease	0,75	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,72	low_impact	-3,54	low_impact	-1,48	high_impact	2,11	0,13	0,8	10,46	9,27	N	0,38	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8495	8495	A	G	MI.1716	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	130	44	M	V	Ata/Gta	-0,8	0	0	possibly_damaging	0,75	neutral	0,44	neutral	1,99	neutral	-0,32	neutral	-0,81	low_impact	1,78	neutral	1	neutral	0,88	deleterious	0,47	7,19	0,84955088	0,9	neutral	0,2	neutral	0,13	neutral	0,49	neutral	0,1	8	neutral	0,75	neutral	0,35	neutral	-3	neutral	0,34	low_impact	-1,21	medium_impact	0,23	medium_impact	0,43	0,37	0,85	7,35	9,56	N	0,5	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11155	11155	C	G	MI.17160	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	396	132	I	M	atC/atG	7,44	0,96	0	probably_damaging	1	neutral	0,27	neutral	4,6	neutral	-1,03	neutral	-2,12	low_impact	1,68	neutral	0,82	damaging	0,27	deleterious	3,28	22,8	0,12	0,4	NA	NA	neutral	0,44	disease	0,7	neutral	0,43	1	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,7	low_impact	-3,54	medium_impact	-0,04	medium_impact	0,54	0,35	0,8	10,46	9,27	P	0,54	P	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11155	11155	C	A	MI.17161	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	396	132	I	M	atC/atA	7,44	0,96	0	probably_damaging	1	neutral	0,27	neutral	4,6	neutral	-1,03	neutral	-2,12	low_impact	1,68	neutral	0,82	damaging	0,27	deleterious	3,8	23,4	0,12	0,4	NA	NA	neutral	0,44	disease	0,7	neutral	0,43	1	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,7	low_impact	-3,54	medium_impact	-0,04	medium_impact	0,54	0,35	0,8	10,46	9,27	P	0,54	P	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11156	11156	A	C	MI.17162	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	397	133	I	L	Atc/Ctc	-7,78	0	0	probably_damaging	1	deleterious	0,03	neutral	4,29	neutral	-2,19	neutral	-1,5	medium_impact	3,13	damaging	0,53	damaging	0,12	deleterious	3,74	23,3	0,13	0,4	NA	NA	disease	0,6	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,72	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,97	0,31	0,8	46,84	9,25	N	0,37	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11156	11156	A	G	MI.17163	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	397	133	I	V	Atc/Gtc	-7,78	0	0	probably_damaging	1	neutral	0,05	neutral	4,35	neutral	-1,15	neutral	-0,76	medium_impact	2,69	damaging	0,57	damaging	0,16	deleterious	3,01	22,3	0,28	0,45	NA	NA	neutral	0,42	disease	0,66	neutral	0,4	2	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,69	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,54	0,44	0,8	46,84	9,25	N	0,4	N	0,75	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11156	11156	A	T	MI.17164	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	397	133	I	F	Atc/Ttc	-7,78	0	0	probably_damaging	1	deleterious	0	neutral	4,17	deleterious	-5,1	deleterious	-3,04	high_impact	4,11	damaging	0,55	damaging	0,14	deleterious	3,71	23,3	0,03	0,35	NA	NA	disease	0,74	disease	0,79	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,94	0,33	0,8	46,84	9,25	N	0,43	N	0,96	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11157	11157	T	G	MI.17165	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	398	133	I	S	aTc/aGc	8,59	1	0	probably_damaging	1	deleterious	0	neutral	4,19	deleterious	-5,08	deleterious	-4,58	high_impact	4,46	damaging	0,57	damaging	0,16	deleterious	4,24	23,9	0,01	0,35	NA	NA	disease	0,83	disease	0,76	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,29	0,12	0,8	46,84	9,25	P	0,59	P	0,95	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11157	11157	T	C	MI.17166	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	398	133	I	T	aTc/aCc	8,59	1	0	probably_damaging	1	deleterious	0	neutral	4,24	deleterious	-4,52	deleterious	-3,82	high_impact	4,11	neutral	0,6	damaging	0,13	deleterious	3,37	22,9	0,02	0,35	NA	NA	disease	0,73	disease	0,76	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	2,94	0,14	0,8	46,84	9,25	P	0,61	P	0,96	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11157	11157	T	A	MI.17167	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	398	133	I	N	aTc/aAc	8,59	1	0	probably_damaging	1	deleterious	0	neutral	4,18	deleterious	-6,43	deleterious	-5,35	high_impact	4,46	damaging	0,54	damaging	0,14	deleterious	4,4	24,1	0,02	0,35	NA	NA	disease	0,83	disease	0,78	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,29	0,07	0,8	46,84	9,25	P	0,59	P	0,99	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11158	11158	C	A	MI.17168	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	399	133	I	M	atC/atA	7,44	1	0	probably_damaging	1	deleterious	0,01	neutral	4,19	deleterious	-4,18	neutral	-2,21	high_impact	3,65	damaging	0,6	damaging	0,14	deleterious	3,69	23,3	0,05	0,35	NA	NA	disease	0,64	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-3,54	medium_impact	-0,92	high_impact	2,49	0,35	0,8	46,84	9,25	P	0,61	P	0,76	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11158	11158	C	G	MI.17169	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	399	133	I	M	atC/atG	7,44	1	0	probably_damaging	1	deleterious	0,01	neutral	4,19	deleterious	-4,18	neutral	-2,21	high_impact	3,65	damaging	0,6	damaging	0,14	deleterious	3,25	22,8	0,05	0,35	NA	NA	disease	0,64	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-3,54	medium_impact	-0,92	high_impact	2,49	0,35	0,8	46,84	9,25	P	0,6	P	0,76	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8495	8495	A	T	MI.1717	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	130	44	M	L	Ata/Tta	-0,8	0	0	possibly_damaging	0,66	neutral	0,45	neutral	2,09	neutral	1,4	neutral	-0,78	neutral_impact	0,68	neutral	1	neutral	0,95	neutral	1	10,66	0,70300388	0,85	neutral	0,18	neutral	0,07	neutral	0,34	neutral	0,04	9	neutral	0,65	neutral	0,4	neutral	-3	neutral	0,3	low_impact	-1,03	medium_impact	0,24	medium_impact	-0,52	0,47	0,85	7,35	9,56	N	0,52	P	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11159	11159	A	T	MI.17170	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	400	134	T	S	Acc/Tcc	-5,47	0	0	probably_damaging	1	neutral	0,42	neutral	4,75	neutral	0,13	deleterious	-2,86	low_impact	1,83	neutral	0,69	neutral	0,66	deleterious	3,22	22,7	0,4	0,5	NA	NA	disease	0,56	neutral	0,4	neutral	0,45	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,8	low_impact	-3,54	medium_impact	0,12	medium_impact	0,68	0,64	0,8	44,01	8,3	N	0,38	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11159	11159	A	C	MI.17171	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	400	134	T	P	Acc/Ccc	-5,47	0	0	probably_damaging	1	neutral	0,2	neutral	4,57	neutral	-2,9	deleterious	-4,44	medium_impact	3,5	neutral	0,67	neutral	0,46	deleterious	3,41	23	0,04	0,35	NA	NA	disease	0,81	disease	0,78	disease	0,76	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,87	low_impact	-3,54	medium_impact	-0,14	high_impact	2,34	0,34	0,8	44,01	8,3	N	0,44	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11159	11159	A	G	MI.17172	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	400	134	T	A	Acc/Gcc	-5,47	0	0	probably_damaging	1	neutral	0,5	neutral	4,68	neutral	1,3	deleterious	-3,52	low_impact	1,83	neutral	0,67	neutral	0,7	deleterious	3,43	23	0,29	0,45	NA	NA	disease	0,54	disease	0,58	disease	0,57	1	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,79	low_impact	-3,54	medium_impact	0,2	medium_impact	0,68	0,28	0,8	44,01	8,3	N	0,34	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11160	11160	C	A	MI.17173	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	401	134	T	N	aCc/aAc	4,67	1	0	probably_damaging	1	neutral	0,31	neutral	4,61	neutral	-1,76	deleterious	-3,72	medium_impact	3,15	neutral	0,71	neutral	0,5	deleterious	3,62	23,2	0,24	0,45	NA	NA	disease	0,75	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	0,01	medium_impact	1,99	0,51	0,8	44,01	8,3	P	0,61	P	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11160	11160	C	T	MI.17174	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	401	134	T	I	aCc/aTc	4,67	1	0	probably_damaging	1	neutral	0,46	neutral	4,64	neutral	0,02	deleterious	-4,44	low_impact	1,62	neutral	0,72	neutral	0,58	deleterious	3,92	23,5	0,12	0,4	NA	NA	disease	0,71	disease	0,63	disease	0,55	1	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,83	low_impact	-3,54	medium_impact	0,16	medium_impact	0,48	0,66	0,8	44,01	8,3	P	0,51	P	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11160	11160	C	G	MI.17175	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	401	134	T	S	aCc/aGc	4,67	1	0	probably_damaging	1	neutral	0,42	neutral	4,75	neutral	0,13	deleterious	-2,86	low_impact	1,83	neutral	0,69	neutral	0,66	deleterious	3,46	23	0,4	0,5	NA	NA	disease	0,56	neutral	0,4	neutral	0,45	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,8	low_impact	-3,54	medium_impact	0,12	medium_impact	0,68	0,64	0,8	44,01	8,3	P	0,55	P	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11162	11162	C	G	MI.17176	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	403	135	R	G	Cga/Gga	-11,7	0	0	possibly_damaging	0,88	neutral	0,83	neutral	4,64	neutral	0,03	deleterious	-5,39	low_impact	0,82	neutral	0,64	neutral	0,4	deleterious	4,16	23,8	0,09	0,35	NA	NA	neutral	0,48	disease	0,7	neutral	0,39	2	neutral	0,86	deleterious	0,48	neutral	-3	deleterious	0,79	low_impact	-1,53	medium_impact	0,59	medium_impact	-0,32	0,19	0,8	14,38	16,18	N	0,26	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11162	11162	C	T	MI.17177	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	403	135	R	W	Cga/Tga	-11,7	0	0	probably_damaging	0,99	neutral	0,19	neutral	4,63	neutral	-2,47	deleterious	-6,17	medium_impact	2,65	neutral	0,63	damaging	0,22	deleterious	5,15	25,4	0,13	0,4	NA	NA	disease	0,9	disease	0,78	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,89	low_impact	-2,59	medium_impact	-0,15	medium_impact	1,5	0,66	0,8	14,38	16,18	N	0,35	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11163	11163	G	C	MI.17178	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	404	135	R	P	cGa/cCa	3,52	0,97	0	probably_damaging	0,97	neutral	0,27	neutral	4,6	neutral	-2,61	deleterious	-5,4	high_impact	3,54	neutral	0,61	neutral	0,3	deleterious	4,28	24	0,02	0,35	NA	NA	disease	0,91	disease	0,87	disease	0,87	7	neutral	0,97	neutral	0,15	deleterious	2	deleterious	0,91	low_impact	-2,14	medium_impact	-0,04	high_impact	2,38	0,12	0,8	14,38	16,18	P	0,55	P	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11163	11163	G	T	MI.17179	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	404	135	R	L	cGa/cTa	3,52	0,97	0	possibly_damaging	0,88	neutral	0,72	neutral	4,77	neutral	1,37	deleterious	-5,41	low_impact	1,76	neutral	0,64	neutral	0,35	deleterious	4,34	24	0,09	0,35	NA	NA	disease	0,91	disease	0,78	disease	0,81	6	neutral	0,85	neutral	0,42	neutral	-3	deleterious	0,88	low_impact	-1,53	medium_impact	0,43	medium_impact	0,62	0,05	0,8	14,38	16,18	N	0,47	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8495	8495	A	C	MI.1718	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	130	44	M	L	Ata/Cta	-0,8	0	0	possibly_damaging	0,66	neutral	0,45	neutral	2,09	neutral	1,4	neutral	-0,78	neutral_impact	0,68	neutral	1	neutral	0,95	neutral	0,92	10,21	0,70300388	0,85	neutral	0,18	neutral	0,07	neutral	0,34	neutral	0,04	9	neutral	0,65	neutral	0,4	neutral	-3	neutral	0,3	low_impact	-1,03	medium_impact	0,24	medium_impact	-0,52	0,47	0,85	7,35	9,56	N	0,53	P	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11163	11163	G	A	MI.17180	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	404	135	R	Q	cGa/cAa	3,52	0,97	0	possibly_damaging	0,83	neutral	0,43	neutral	4,61	neutral	-1,52	deleterious	-3,08	medium_impact	2,65	neutral	0,64	damaging	0,28	deleterious	4,45	24,2	0,2	0,45	NA	NA	disease	0,83	disease	0,79	disease	0,8	6	neutral	0,83	neutral	0,3	NA	0	deleterious	0,83	low_impact	-1,37	medium_impact	0,13	medium_impact	1,5	0,81	0,85	14,38	16,18	P	0,55	P	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11165	11165	T	C	MI.17181	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	406	136	W	R	Tga/Cga	-4,09	0	0	probably_damaging	1	deleterious	0	neutral	4,46	neutral	-2,3	deleterious	-10,83	high_impact	4,45	neutral	0,64	damaging	0,12	deleterious	3,52	23,1	0,04	0,35	NA	NA	disease	0,91	disease	0,88	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,28	0,03	0,8	47,28	9,26	P	0,58	P	0,97	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11165	11165	T	G	MI.17182	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	406	136	W	G	Tga/Gga	-4,09	0	0	probably_damaging	1	neutral	0,05	neutral	4,48	neutral	-2,8	deleterious	-10,06	high_impact	3,9	neutral	0,63	damaging	0,17	deleterious	3,83	23,4	0,05	0,35	NA	NA	disease	0,86	disease	0,85	disease	0,81	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	-0,52	high_impact	2,73	0,04	0,8	47,28	9,26	N	0,49	N	0,97	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11166	11166	G	T	MI.17183	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	407	136	W	L	tGa/tTa	7,44	1	0	probably_damaging	1	deleterious	0,01	neutral	4,51	neutral	-2,69	deleterious	-10,06	high_impact	3,55	neutral	0,62	damaging	0,13	deleterious	4,2	23,9	0,06	0,35	NA	NA	disease	0,86	disease	0,84	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-3,54	medium_impact	-0,92	high_impact	2,39	0,06	0,8	47,28	9,26	P	0,62	P	0,97	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11166	11166	G	C	MI.17184	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	407	136	W	S	tGa/tCa	7,44	1	0	probably_damaging	1	deleterious	0	neutral	4,46	neutral	-2,58	deleterious	-10,83	high_impact	3,75	neutral	0,64	damaging	0,17	deleterious	3,98	23,6	0,05	0,35	NA	NA	disease	0,92	disease	0,84	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	2,58	0,04	0,8	47,28	9,26	P	0,63	P	0,93	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11167	11167	A	T	MI.17185	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	408	136	W	C	tgA/tgT	7,21	1	0,02	probably_damaging	1	deleterious	0	neutral	4,43	deleterious	-5,13	deleterious	-10,06	high_impact	4,1	neutral	0,63	damaging	0,11	deleterious	4,06	23,7	0,04	0,35	NA	NA	disease	0,9	disease	0,87	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	2,93	0,08	0,8	47,28	9,26	P	0,61	P	0,98	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11167	11167	A	C	MI.17186	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	408	136	W	C	tgA/tgC	7,21	1	0,02	probably_damaging	1	deleterious	0	neutral	4,43	deleterious	-5,13	deleterious	-10,06	high_impact	4,1	neutral	0,63	damaging	0,11	deleterious	3,98	23,6	0,04	0,35	NA	NA	disease	0,9	disease	0,87	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	2,93	0,08	0,8	47,28	9,26	P	0,61	P	0,98	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11168	11168	G	T	MI.17187	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	409	137	G	C	Ggc/Tgc	0,06	0,94	0	probably_damaging	1	deleterious	0	neutral	4,49	deleterious	-6,5	deleterious	-6,96	high_impact	4,5	damaging	0,32	damaging	0,03	deleterious	4,17	23,8	0,08	0,35	NA	NA	disease	0,89	disease	0,69	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,09	0,8	47,49	9,15	P	0,63	P	0,98	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11168	11168	G	C	MI.17188	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	409	137	G	R	Ggc/Cgc	0,06	0,94	0	probably_damaging	1	deleterious	0	neutral	4,58	neutral	-1,7	deleterious	-6,19	high_impact	4,5	damaging	0,39	damaging	0,04	deleterious	3,93	23,5	0,08	0,35	NA	NA	disease	0,87	disease	0,73	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,58	0,8	47,49	9,15	P	0,67	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11168	11168	G	A	MI.17189	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	409	137	G	S	Ggc/Agc	0,06	0,94	0	probably_damaging	1	neutral	0,06	neutral	4,59	neutral	-2,42	deleterious	-4,64	medium_impact	3,26	damaging	0,34	damaging	0,07	deleterious	4,12	23,8	0,13	0,4	NA	NA	disease	0,85	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,88	low_impact	-3,54	medium_impact	-0,47	high_impact	2,1	0,5	0,8	47,49	9,15	P	0,64	P	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8496	8496	T	A	MI.1719	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	131	44	M	K	aTa/aAa	-5,19	0	0	possibly_damaging	0,88	neutral	1	neutral	2,06	neutral	1,08	neutral	-1,44	neutral_impact	0,44	neutral	1	neutral	0,84	deleterious	2,65	20,5	0,44486802	0,85	neutral	0,45	neutral	0,26	neutral	0,33	neutral	0,13	8	neutral	0,88	deleterious	0,56	neutral	-3	deleterious	0,58	low_impact	-1,58	high_impact	1,98	medium_impact	-0,72	0,43	0,85	7,35	9,56	N	0,31	N	0,52	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11169	11169	G	A	MI.17190	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	410	137	G	D	gGc/gAc	5,13	1	0	probably_damaging	1	deleterious	0	neutral	4,54	neutral	-2,91	deleterious	-5,42	high_impact	4,5	damaging	0,3	damaging	0,05	deleterious	3,8	23,4	0,08	0,35	NA	NA	disease	0,88	disease	0,75	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,13	0,8	47,49	9,15	P	0,78	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11169	11169	G	C	MI.17191	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	410	137	G	A	gGc/gCc	5,13	1	0	probably_damaging	1	deleterious	0	neutral	4,55	neutral	-2,45	deleterious	-4,64	high_impact	4,5	damaging	0,46	damaging	0,07	deleterious	3,08	22,5	0,17	0,45	NA	NA	disease	0,76	disease	0,68	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,36	0,8	47,49	9,15	P	0,64	P	0,76	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11169	11169	G	T	MI.17192	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	410	137	G	V	gGc/gTc	5,13	1	0	probably_damaging	1	deleterious	0	neutral	4,51	deleterious	-3,95	deleterious	-6,96	high_impact	4,5	damaging	0,38	damaging	0,05	deleterious	3,73	23,3	0,07	0,35	NA	NA	disease	0,88	disease	0,7	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,08	0,8	47,49	9,15	P	0,7	P	0,98	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11171	11171	A	C	MI.17193	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	412	138	N	H	Aac/Cac	-9,16	0	0	possibly_damaging	0,76	neutral	0,46	neutral	4,57	neutral	-0,4	deleterious	-3,58	low_impact	1,52	neutral	0,73	neutral	0,44	deleterious	3,11	22,5	0,67	0,7	NA	NA	disease	0,67	neutral	0,39	disease	0,51	0	neutral	0,75	neutral	0,35	neutral	-3	deleterious	0,78	low_impact	-1,19	medium_impact	0,16	medium_impact	0,38	0,11	0,8	18,52	17,16	N	0,27	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11171	11171	A	T	MI.17194	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	412	138	N	Y	Aac/Tac	-9,16	0	0	benign	0,03	neutral	1	neutral	4,63	neutral	-1,56	deleterious	-5,64	neutral_impact	0,03	neutral	0,67	neutral	0,61	deleterious	3,68	23,3	0,23	0,45	NA	NA	disease	0,52	neutral	0,38	neutral	0,45	1	neutral	0,03	deleterious	0,99	neutral	-6	deleterious	0,76	medium_impact	0,7	high_impact	1,88	low_impact	-1,1	0,16	0,8	18,52	17,16	N	0,25	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11171	11171	A	G	MI.17195	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	412	138	N	D	Aac/Gac	-9,16	0	0	benign	0,37	neutral	0,18	neutral	4,62	neutral	0,44	deleterious	-3,68	medium_impact	2,4	neutral	0,75	neutral	0,48	deleterious	3,83	23,4	0,81	0,85	NA	NA	disease	0,65	disease	0,6	disease	0,67	3	neutral	0,79	neutral	0,41	neutral	-3	deleterious	0,78	medium_impact	-0,5	medium_impact	-0,17	medium_impact	1,25	0,28	0,8	18,52	17,16	N	0,37	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11172	11172	A	C	MI.17196	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	413	138	N	T	aAc/aCc	4,67	0,69	0	benign	0,03	neutral	0,33	neutral	4,65	neutral	0,52	deleterious	-4,36	medium_impact	2,29	neutral	0,77	neutral	0,56	deleterious	3,82	23,4	0,59	0,65	NA	NA	disease	0,68	neutral	0,33	disease	0,5	0	neutral	0,65	deleterious	0,65	neutral	-3	deleterious	0,75	medium_impact	0,7	medium_impact	0,03	medium_impact	1,14	0,27	0,8	18,52	17,16	N	0,38	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11172	11172	A	G	MI.17197	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	413	138	N	S	aAc/aGc	4,67	0,69	0	benign	0,03	neutral	0,41	neutral	4,64	neutral	0,45	deleterious	-3,59	neutral_impact	0,18	neutral	0,72	neutral	0,83	deleterious	2,48	19,36	0,77	0,8	NA	NA	disease	0,55	neutral	0,35	neutral	0,46	1	neutral	0,56	deleterious	0,69	neutral	-6	deleterious	0,77	medium_impact	0,7	medium_impact	0,11	medium_impact	-0,95	0,29	0,8	18,52	17,16	N	0,31	N	0,85	polymorphism	1	0,07	rs2853489	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11172	11172	A	T	MI.17198	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	413	138	N	I	aAc/aTc	4,67	0,69	0	benign	0,03	neutral	0,33	neutral	4,58	neutral	-2,41	deleterious	-6,57	medium_impact	2,2	neutral	0,72	neutral	0,53	deleterious	4,41	24,1	0,2	0,45	NA	NA	disease	0,81	disease	0,59	disease	0,7	4	neutral	0,65	deleterious	0,65	neutral	-3	deleterious	0,82	medium_impact	0,7	medium_impact	0,03	medium_impact	1,05	0,1	0,8	18,52	17,16	N	0,41	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11173	11173	C	A	MI.17199	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	414	138	N	K	aaC/aaA	1,68	0,54	0	benign	0,37	neutral	0,24	neutral	4,75	neutral	0,73	deleterious	-4,39	low_impact	1,74	neutral	0,77	neutral	0,38	deleterious	4,41	24,1	0,68	0,7	NA	NA	disease	0,77	disease	0,62	disease	0,7	4	neutral	0,72	neutral	0,44	neutral	-6	deleterious	0,82	medium_impact	-0,5	medium_impact	-0,08	medium_impact	0,6	0,38	0,8	18,52	17,16	N	0,28	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8606	8606	C	A	MI.172	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	80	27	P	H	cCc/cAc	5,45	1	0	probably_damaging	1	neutral	0,54	neutral	4,34	neutral	-2,05	deleterious	-8,12	high_impact	3,86	neutral	0,73	neutral	0,43	deleterious	3,83	23,4	0,28	0,65	neutral	0,39	disease	0,82	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,33	high_impact	2,21	0,46	0,9	48,23	8,81	N	0,49	N	0,67	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8496	8496	T	C	MI.1720	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	131	44	M	T	aTa/aCa	-5,19	0	0	possibly_damaging	0,88	neutral	0,67	neutral	2,1	neutral	1,46	neutral	0,24	neutral_impact	-0,7	neutral	1	neutral	0,98	deleterious	0,29	5,57	0,8102732	0,9	neutral	0,12	neutral	0,14	neutral	0,41	neutral	0,07	9	neutral	0,86	neutral	0,4	neutral	-3	deleterious	0,51	low_impact	-1,58	medium_impact	0,47	low_impact	-1,7	0,16	0,85	7,35	9,56	N	0,41	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11173	11173	C	G	MI.17200	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	414	138	N	K	aaC/aaG	1,68	0,54	0	benign	0,37	neutral	0,24	neutral	4,75	neutral	0,73	deleterious	-4,39	low_impact	1,74	neutral	0,77	neutral	0,38	deleterious	3,97	23,6	0,68	0,7	NA	NA	disease	0,77	disease	0,62	disease	0,7	4	neutral	0,72	neutral	0,44	neutral	-6	deleterious	0,82	medium_impact	-0,5	medium_impact	-0,08	medium_impact	0,6	0,38	0,8	18,52	17,16	N	0,28	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11174	11174	C	A	MI.17201	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	415	139	Q	K	Cag/Aag	-4,55	0	0	probably_damaging	1	deleterious	0	neutral	4,72	neutral	1,44	deleterious	-3,1	medium_impact	2,91	neutral	0,63	damaging	0,14	deleterious	3,98	23,6	0,49	0,55	NA	NA	disease	0,86	disease	0,67	disease	0,74	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	medium_impact	1,75	0,24	0,8	46,62	9,3	N	0,34	N	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11174	11174	C	G	MI.17202	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	415	139	Q	E	Cag/Gag	-4,55	0	0	probably_damaging	1	deleterious	0	neutral	4,6	neutral	0,5	neutral	-2,32	medium_impact	2,71	neutral	0,68	damaging	0,13	deleterious	3,04	22,4	0,55	0,6	NA	NA	disease	0,79	disease	0,68	disease	0,71	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	medium_impact	1,56	0,28	0,8	46,62	9,3	N	0,29	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11175	11175	A	T	MI.17203	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	416	139	Q	L	cAg/cTg	5,6	1	0	probably_damaging	1	deleterious	0	neutral	4,54	neutral	-1,31	deleterious	-5,42	high_impact	3,75	neutral	0,64	damaging	0,09	deleterious	3,89	23,5	0,12	0,4	NA	NA	disease	0,88	disease	0,66	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	2,58	0,11	0,8	46,62	9,3	P	0,61	P	0,97	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11175	11175	A	C	MI.17204	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	416	139	Q	P	cAg/cCg	5,6	1	0	probably_damaging	1	deleterious	0	neutral	4,52	neutral	-2,6	deleterious	-4,64	medium_impact	2,98	neutral	0,64	damaging	0,14	deleterious	3,37	22,9	0,09	0,35	NA	NA	disease	0,88	disease	0,65	disease	0,73	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,91	low_impact	-3,54	low_impact	-1,48	medium_impact	1,82	0,17	0,8	46,62	9,3	P	0,52	P	0,97	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11175	11175	A	G	MI.17205	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	416	139	Q	R	cAg/cGg	5,6	1	0	probably_damaging	1	neutral	0,08	neutral	4,64	neutral	1,08	deleterious	-3,1	medium_impact	2,58	neutral	0,67	damaging	0,11	deleterious	3,52	23,1	0,5	0,6	NA	NA	disease	0,84	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,89	low_impact	-3,54	medium_impact	-0,39	medium_impact	1,43	0,2	0,8	46,62	9,3	P	0,58	P	0,88	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11176	11176	G	T	MI.17206	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	417	139	Q	H	caG/caT	8,59	1	0,01	probably_damaging	1	deleterious	0,01	neutral	4,53	neutral	-1,82	deleterious	-3,87	high_impact	3,75	neutral	0,64	damaging	0,1	deleterious	3,55	23,1	0,33	0,5	NA	NA	disease	0,79	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,54	medium_impact	-0,92	high_impact	2,58	0,31	0,8	46,62	9,3	P	0,6	P	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11176	11176	G	C	MI.17207	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	417	139	Q	H	caG/caC	8,59	1	0,01	probably_damaging	1	deleterious	0,01	neutral	4,53	neutral	-1,82	deleterious	-3,87	high_impact	3,75	neutral	0,64	damaging	0,1	deleterious	3,42	23	0,33	0,5	NA	NA	disease	0,79	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,54	medium_impact	-0,92	high_impact	2,58	0,31	0,8	46,62	9,3	P	0,6	P	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11177	11177	C	A	MI.17208	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	418	140	P	T	Cca/Aca	0,75	0,21	0,01	benign	0,04	neutral	0,41	neutral	4,56	neutral	-1,82	neutral	2,73	neutral_impact	0,7	neutral	0,71	neutral	0,97	neutral	1,05	10,94	0,3	0,45	NA	NA	neutral	0,15	neutral	0,15	neutral	0,22	6	neutral	0,56	deleterious	0,69	neutral	-6	deleterious	0,66	medium_impact	0,58	medium_impact	0,11	medium_impact	-0,43	0,48	0,8	31,59	28,53	N	0,47	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11177	11177	C	T	MI.17209	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	418	140	P	S	Cca/Tca	0,75	0,21	0,01	benign	0,36	neutral	0,2	neutral	4,62	neutral	-1,35	neutral	0,85	medium_impact	2,13	neutral	0,76	neutral	0,84	deleterious	3,73	23,3	0,29	0,45	NA	NA	neutral	0,47	neutral	0,34	neutral	0,34	3	neutral	0,76	neutral	0,42	neutral	-3	deleterious	0,73	medium_impact	-0,48	medium_impact	-0,14	medium_impact	0,98	0,27	0,8	31,59	28,53	N	0,41	N	0,44	polymorphism	1	0,02	rs28358284	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8497	8497	A	T	MI.1721	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	132	44	M	I	atA/atT	-6,35	0	0	possibly_damaging	0,82	neutral	0,36	neutral	1,99	neutral	-0,42	neutral	-1,11	low_impact	1,01	neutral	1	neutral	0,95	neutral	1,49	13,26	0,7567226	0,85	neutral	0,18	neutral	0,04	neutral	0,35	neutral	0,04	9	neutral	0,83	neutral	0,27	neutral	-3	neutral	0,42	low_impact	-1,38	medium_impact	0,15	medium_impact	-0,23	0,38	0,85	7,35	9,56	P	0,53	P	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11177	11177	C	G	MI.17210	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	418	140	P	A	Cca/Gca	0,75	0,21	0,01	benign	0,01	neutral	0,22	neutral	4,59	neutral	-0,87	neutral	0,56	low_impact	1,25	neutral	0,74	neutral	0,96	neutral	1,07	11,06	0,32	0,5	NA	NA	neutral	0,17	neutral	0,19	neutral	0,23	5	neutral	0,77	deleterious	0,61	neutral	-6	deleterious	0,69	medium_impact	1,16	medium_impact	-0,11	medium_impact	0,11	0,39	0,8	31,59	28,53	N	0,49	N	0,05	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11178	11178	C	G	MI.17211	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	419	140	P	R	cCa/cGa	0,06	0	0	possibly_damaging	0,75	deleterious	0,03	neutral	4,54	neutral	-1,31	neutral	-0,57	medium_impact	2,98	neutral	0,8	neutral	0,46	deleterious	3,51	23,1	0,12	0,4	NA	NA	disease	0,68	neutral	0,46	disease	0,51	0	neutral	0,98	neutral	0,14	deleterious	4	deleterious	0,77	low_impact	-1,17	medium_impact	-0,64	medium_impact	1,82	0,16	0,8	31,59	28,53	N	0,39	N	0,6	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11178	11178	C	A	MI.17212	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	419	140	P	Q	cCa/cAa	0,06	0	0	possibly_damaging	0,81	deleterious	0,04	neutral	4,6	neutral	-1,88	neutral	-0,48	low_impact	1,75	neutral	0,77	neutral	0,78	deleterious	3,97	23,6	0,17	0,45	NA	NA	disease	0,51	neutral	0,29	neutral	0,5	0	neutral	0,97	neutral	0,12	deleterious	1	deleterious	0,72	low_impact	-1,31	medium_impact	-0,57	medium_impact	0,61	0,26	0,8	31,59	28,53	N	0,43	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11178	11178	C	T	MI.17213	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	419	140	P	L	cCa/cTa	0,06	0	0	benign	0,36	neutral	0,05	neutral	4,6	neutral	-2,64	neutral	-0,55	medium_impact	2,09	neutral	0,79	neutral	0,72	deleterious	4,32	24	0,17	0,45	NA	NA	disease	0,58	neutral	0,38	neutral	0,49	0	neutral	0,94	neutral	0,35	neutral	-3	deleterious	0,74	medium_impact	-0,48	medium_impact	-0,52	medium_impact	0,94	0,56	0,8	31,59	28,53	N	0,41	N	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11180	11180	G	A	MI.17214	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	421	141	E	K	Gaa/Aaa	-0,63	0	0	benign	0,3	deleterious	0,01	neutral	4,64	neutral	-0,57	deleterious	-3	medium_impact	2,94	damaging	0,57	neutral	0,46	deleterious	4,45	24,2	0,2	0,45	NA	NA	disease	0,9	disease	0,58	disease	0,69	4	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,91	medium_impact	-0,37	medium_impact	-0,92	medium_impact	1,78	0,72	0,85	42,48	8,42	N	0,38	N	0,41	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11180	11180	G	C	MI.17215	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	421	141	E	Q	Gaa/Caa	-0,63	0	0	probably_damaging	0,94	deleterious	0,02	neutral	4,51	neutral	-1,06	neutral	-2,25	medium_impact	3,07	damaging	0,59	neutral	0,57	deleterious	3,35	22,9	0,47	0,55	NA	NA	disease	0,78	disease	0,51	disease	0,6	2	deleterious	0,99	neutral	0,04	deleterious	5	deleterious	0,84	low_impact	-1,84	medium_impact	-0,75	medium_impact	1,91	0,37	0,8	42,48	8,42	N	0,41	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11181	11181	A	C	MI.17216	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	422	141	E	A	gAa/gCa	7,44	1	0	possibly_damaging	0,9	deleterious	0,01	neutral	4,53	neutral	-0,51	deleterious	-4,39	medium_impact	3,07	neutral	0,61	neutral	0,66	deleterious	3,62	23,2	0,18	0,45	NA	NA	disease	0,82	disease	0,55	disease	0,69	4	deleterious	1	neutral	0,06	deleterious	4	deleterious	0,87	low_impact	-1,61	medium_impact	-0,92	medium_impact	1,91	0,43	0,8	42,48	8,42	P	0,6	P	0,77	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11181	11181	A	G	MI.17217	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	422	141	E	G	gAa/gGa	7,44	1	0	probably_damaging	0,96	deleterious	0,01	neutral	4,48	neutral	-2,17	deleterious	-5,23	medium_impact	3,25	damaging	0,57	neutral	0,58	deleterious	4,17	23,8	0,18	0,45	NA	NA	disease	0,8	disease	0,62	disease	0,69	4	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,87	low_impact	-2,01	medium_impact	-0,92	high_impact	2,09	0,19	0,8	42,48	8,42	P	0,56	P	0,87	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11181	11181	A	T	MI.17218	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	422	141	E	V	gAa/gTa	7,44	1	0	probably_damaging	0,98	deleterious	0	neutral	4,47	neutral	-2,68	deleterious	-5,23	high_impact	3,67	damaging	0,56	neutral	0,48	deleterious	4,05	23,7	0,09	0,35	NA	NA	disease	0,9	disease	0,62	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-2,31	low_impact	-1,48	high_impact	2,51	0,47	0,8	42,48	8,42	P	0,58	P	0,93	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11182	11182	A	C	MI.17219	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	423	141	E	D	gaA/gaC	8,59	1	0	probably_damaging	0,92	deleterious	0,03	neutral	4,54	neutral	-1,33	neutral	-2,27	low_impact	1,88	damaging	0,6	neutral	0,62	deleterious	3,63	23,2	0,55	0,6	NA	NA	disease	0,74	neutral	0,46	neutral	0,49	0	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,86	low_impact	-1,71	medium_impact	-0,64	medium_impact	0,73	0,35	0,8	42,48	8,42	P	0,61	P	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8497	8497	A	C	MI.1722	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	132	44	M	I	atA/atC	-6,35	0	0	possibly_damaging	0,82	neutral	0,36	neutral	1,99	neutral	-0,42	neutral	-1,11	low_impact	1,01	neutral	1	neutral	0,95	neutral	1,41	12,85	0,7567226	0,85	neutral	0,18	neutral	0,04	neutral	0,35	neutral	0,04	9	neutral	0,83	neutral	0,27	neutral	-3	neutral	0,42	low_impact	-1,38	medium_impact	0,15	medium_impact	-0,23	0,38	0,85	7,35	9,56	P	0,53	P	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11182	11182	A	T	MI.17220	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	423	141	E	D	gaA/gaT	8,59	1	0	probably_damaging	0,92	deleterious	0,03	neutral	4,54	neutral	-1,33	neutral	-2,27	low_impact	1,88	damaging	0,6	neutral	0,62	deleterious	3,73	23,3	0,55	0,6	NA	NA	disease	0,74	neutral	0,46	neutral	0,49	0	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,86	low_impact	-1,71	medium_impact	-0,64	medium_impact	0,73	0,35	0,8	42,48	8,42	P	0,62	P	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11183	11183	C	T	MI.17221	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	424	142	R	C	Cgc/Tgc	-0,17	0,57	0	probably_damaging	1	deleterious	0	neutral	4,48	deleterious	-6,01	deleterious	-6,18	high_impact	4,45	damaging	0,44	damaging	0,01	deleterious	4,94	25	0,06	0,35	NA	NA	disease	0,92	disease	0,74	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,28	0,75	0,85	46,19	9,45	P	0,56	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11183	11183	C	G	MI.17222	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	424	142	R	G	Cgc/Ggc	-0,17	0,57	0	probably_damaging	1	deleterious	0	neutral	4,52	neutral	-2,97	deleterious	-5,41	high_impact	3,9	damaging	0,46	damaging	0,05	deleterious	4,14	23,8	0,05	0,35	NA	NA	disease	0,83	disease	0,74	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	2,73	0,19	0,8	46,19	9,45	N	0,43	N	0,98	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11183	11183	C	A	MI.17223	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	424	142	R	S	Cgc/Agc	-0,17	0,57	0	probably_damaging	1	deleterious	0	neutral	4,77	neutral	-0,64	deleterious	-4,64	high_impact	3,56	damaging	0,44	damaging	0,04	deleterious	4,65	24,5	0,05	0,35	NA	NA	disease	0,89	disease	0,71	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	2,4	0,19	0,8	46,19	9,45	N	0,51	P	0,81	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11184	11184	G	A	MI.17224	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	425	142	R	H	cGc/cAc	1,68	0,95	0	probably_damaging	1	deleterious	0	neutral	4,5	deleterious	-3,24	deleterious	-3,87	high_impact	4,45	damaging	0,49	damaging	0,02	deleterious	4,49	24,3	0,12	0,4	NA	NA	disease	0,87	disease	0,69	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,28	0,85	0,9	46,19	9,45	P	0,56	P	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11184	11184	G	T	MI.17225	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	425	142	R	L	cGc/cTc	1,68	0,95	0	probably_damaging	1	deleterious	0	neutral	4,5	neutral	-2,97	deleterious	-5,41	high_impact	4,45	damaging	0,47	damaging	0,02	deleterious	4,28	24	0,04	0,35	NA	NA	disease	0,94	disease	0,71	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,28	0,05	0,8	46,19	9,45	P	0,58	P	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11184	11184	G	C	MI.17226	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	425	142	R	P	cGc/cCc	1,68	0,95	0	probably_damaging	1	deleterious	0,01	neutral	4,49	deleterious	-3,64	deleterious	-5,41	high_impact	4,11	damaging	0,44	damaging	0,02	deleterious	4,19	23,8	0,02	0,35	NA	NA	disease	0,91	disease	0,82	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,92	low_impact	-3,54	medium_impact	-0,92	high_impact	2,94	0,09	0,8	46,19	9,45	P	0,61	P	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11186	11186	C	G	MI.17227	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	427	143	L	V	Ctg/Gtg	-6,63	0	0	probably_damaging	1	neutral	0,14	neutral	4,59	neutral	-0,47	neutral	-2,19	medium_impact	2,1	neutral	0,61	damaging	0,1	deleterious	3,33	22,9	0,27	0,45	NA	NA	disease	0,56	disease	0,53	neutral	0,47	1	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,24	medium_impact	0,95	0,34	0,8	40,09	8,36	N	0,3	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11186	11186	C	A	MI.17228	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	427	143	L	M	Ctg/Atg	-6,63	0	0	probably_damaging	1	deleterious	0,04	neutral	4,5	neutral	-1,6	neutral	-1,24	medium_impact	2,74	neutral	0,73	neutral	0,4	deleterious	3,65	23,2	0,25	0,45	NA	NA	disease	0,51	neutral	0,35	neutral	0,46	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,78	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,59	0,48	0,8	40,09	8,36	N	0,45	N	0,28	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11187	11187	T	A	MI.17229	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	428	143	L	Q	cTg/cAg	0,29	0,02	0	probably_damaging	1	deleterious	0	neutral	4,46	deleterious	-3,23	deleterious	-4,4	medium_impact	3,29	damaging	0,59	damaging	0,1	deleterious	4,12	23,8	0,03	0,35	NA	NA	disease	0,81	disease	0,55	disease	0,68	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,13	0,08	0,8	40,09	8,36	N	0,32	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8498	8498	A	G	MI.1723	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	133	45	K	E	Aaa/Gaa	-5,89	0	0	possibly_damaging	0,87	neutral	0,39	neutral	1,76	neutral	1,22	neutral	-0,5	medium_impact	2,23	neutral	0,99	neutral	0,81	neutral	1,43	12,93	0,64287435	0,85	neutral	0,15	neutral	0,18	neutral	0,39	neutral	0,12	8	neutral	0,88	neutral	0,26	NA	0	deleterious	0,65	low_impact	-1,54	medium_impact	0,18	medium_impact	0,81	0,6	0,85	20,59	9,8	N	0,49	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11187	11187	T	G	MI.17230	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	428	143	L	R	cTg/cGg	0,29	0,02	0	probably_damaging	1	deleterious	0	neutral	4,46	deleterious	-3,12	deleterious	-4,46	medium_impact	2,94	damaging	0,55	damaging	0,09	deleterious	4,11	23,7	0,02	0,35	NA	NA	disease	0,87	disease	0,66	disease	0,75	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	medium_impact	1,78	0,09	0,8	40,09	8,36	N	0,3	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11187	11187	T	C	MI.17231	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	428	143	L	P	cTg/cCg	0,29	0,02	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-3,82	deleterious	-5,24	high_impact	3,63	damaging	0,54	damaging	0,09	deleterious	3,79	23,4	0,01	0,35	NA	NA	disease	0,83	disease	0,68	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,54	low_impact	-1,48	high_impact	2,47	0,05	0,8	40,09	8,36	N	0,31	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11189	11189	A	G	MI.17232	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	430	144	N	D	Aac/Gac	-2,94	0	0	benign	0,17	neutral	0,11	neutral	4,61	neutral	-0,59	deleterious	-3,6	medium_impact	2,32	neutral	0,77	damaging	0,17	deleterious	3,72	23,3	0,57	0,65	NA	NA	disease	0,64	neutral	0,45	neutral	0,49	0	neutral	0,87	deleterious	0,47	neutral	-3	deleterious	0,79	medium_impact	-0,07	medium_impact	-0,31	medium_impact	1,17	0,22	0,8	32,68	8,13	N	0,33	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11189	11189	A	C	MI.17233	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	430	144	N	H	Aac/Cac	-2,94	0	0	probably_damaging	0,99	deleterious	0,01	neutral	4,65	neutral	0,05	deleterious	-3,54	medium_impact	2,04	neutral	0,74	damaging	0,2	deleterious	3	22,2	0,36	0,5	NA	NA	disease	0,67	neutral	0,41	disease	0,52	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-2,59	medium_impact	-0,92	medium_impact	0,89	0,12	0,8	32,68	8,13	N	0,32	N	0,83	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11189	11189	A	T	MI.17234	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	430	144	N	Y	Aac/Tac	-2,94	0	0	probably_damaging	0,99	deleterious	0	neutral	4,61	neutral	-0,74	deleterious	-5,78	low_impact	1	neutral	0,73	damaging	0,1	deleterious	3,65	23,2	0,13	0,4	NA	NA	disease	0,8	neutral	0,5	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	2	deleterious	0,82	low_impact	-2,59	low_impact	-1,48	medium_impact	-0,14	0,19	0,8	32,68	8,13	N	0,27	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11190	11190	A	C	MI.17235	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	431	144	N	T	aAc/aCc	6,75	0,99	0	probably_damaging	0,94	neutral	0,14	neutral	4,65	neutral	0,12	deleterious	-4,25	low_impact	1,43	neutral	0,75	neutral	0,29	deleterious	3,38	23	0,32	0,5	NA	NA	disease	0,57	neutral	0,19	neutral	0,45	1	neutral	0,97	neutral	0,1	neutral	-2	deleterious	0,75	low_impact	-1,84	medium_impact	-0,24	medium_impact	0,29	0,24	0,8	32,68	8,13	P	0,59	P	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11190	11190	A	T	MI.17236	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	431	144	N	I	aAc/aTc	6,75	0,99	0	probably_damaging	0,98	deleterious	0,02	neutral	4,57	neutral	-2,19	deleterious	-6,54	medium_impact	2,12	neutral	0,71	damaging	0,11	deleterious	3,92	23,5	0,14	0,4	NA	NA	disease	0,8	neutral	0,44	disease	0,65	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,83	low_impact	-2,31	medium_impact	-0,75	medium_impact	0,97	0,17	0,8	32,68	8,13	N	0,51	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11190	11190	A	G	MI.17237	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	431	144	N	S	aAc/aGc	6,75	0,99	0	possibly_damaging	0,81	neutral	0,36	neutral	4,7	neutral	0,72	deleterious	-3,44	neutral_impact	0,68	neutral	0,78	neutral	0,72	deleterious	2,98	22,2	0,49	0,55	NA	NA	neutral	0,38	neutral	0,23	neutral	0,2	6	neutral	0,83	neutral	0,28	neutral	-3	deleterious	0,76	low_impact	-1,31	medium_impact	0,06	medium_impact	-0,45	0,22	0,8	32,68	8,13	P	0,54	P	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11191	11191	C	G	MI.17238	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	432	144	N	K	aaC/aaG	2,37	0,97	0	probably_damaging	0,91	neutral	0,16	neutral	4,74	neutral	1,07	deleterious	-4,24	low_impact	0,96	neutral	0,78	damaging	0,19	deleterious	3,88	23,5	0,42	0,55	NA	NA	disease	0,72	neutral	0,28	disease	0,51	0	neutral	0,95	neutral	0,13	neutral	-2	deleterious	0,82	low_impact	-1,66	medium_impact	-0,2	medium_impact	-0,18	0,28	0,8	32,68	8,13	N	0,41	N	0,57	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11191	11191	C	A	MI.17239	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	432	144	N	K	aaC/aaA	2,37	0,97	0	probably_damaging	0,91	neutral	0,16	neutral	4,74	neutral	1,07	deleterious	-4,24	low_impact	0,96	neutral	0,78	damaging	0,19	deleterious	4,36	24,1	0,42	0,55	NA	NA	disease	0,72	neutral	0,28	disease	0,51	0	neutral	0,95	neutral	0,13	neutral	-2	deleterious	0,82	low_impact	-1,66	medium_impact	-0,2	medium_impact	-0,18	0,28	0,8	32,68	8,13	N	0,41	N	0,57	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8498	8498	A	C	MI.1724	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	133	45	K	Q	Aaa/Caa	-5,89	0	0	probably_damaging	0,95	neutral	0,38	neutral	1,56	neutral	-0,34	neutral	0,34	neutral_impact	0,08	neutral	0,99	neutral	0,97	neutral	1,13	11,4	0,5073837	0,85	neutral	0,16	neutral	0,05	neutral	0,27	neutral	0,04	9	neutral	0,95	neutral	0,22	neutral	-2	deleterious	0,62	low_impact	-1,97	medium_impact	0,17	low_impact	-1,03	0,7	0,85	20,59	9,8	N	0,53	P	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11192	11192	G	A	MI.17240	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	433	145	A	T	Gca/Aca	-4,09	0	0	possibly_damaging	0,48	deleterious	0	neutral	4,21	deleterious	-4,74	deleterious	-3,09	high_impact	3,92	damaging	0,52	neutral	0,39	deleterious	2,37	18,6	0,05	0,35	NA	NA	disease	0,85	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,26	deleterious	5	neutral	0,37	medium_impact	-0,69	low_impact	-1,48	high_impact	2,75	0,72	0,85	46,19	9,28	N	0,47	N	0,82	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11192	11192	G	T	MI.17241	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	433	145	A	S	Gca/Tca	-4,09	0	0	possibly_damaging	0,44	neutral	0,16	neutral	4,36	deleterious	-3,46	neutral	-2,31	medium_impact	2,55	damaging	0,52	neutral	0,51	deleterious	1,86	15,36	0,08	0,35	NA	NA	disease	0,81	disease	0,65	disease	0,7	4	neutral	0,82	neutral	0,36	NA	0	deleterious	0,45	medium_impact	-0,62	medium_impact	-0,2	medium_impact	1,4	0,48	0,8	46,19	9,28	N	0,4	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11192	11192	G	C	MI.17242	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	433	145	A	P	Gca/Cca	-4,09	0	0	benign	0,04	deleterious	0	neutral	4,2	deleterious	-6,18	deleterious	-3,86	high_impact	3,92	damaging	0,5	neutral	0,42	deleterious	2,19	17,41	0,03	0,35	NA	NA	disease	0,87	disease	0,8	disease	0,82	6	deleterious	1	deleterious	0,48	deleterious	2	deleterious	0,68	medium_impact	0,58	low_impact	-1,48	high_impact	2,75	0,44	0,8	46,19	9,28	N	0,5	N	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11193	11193	C	A	MI.17243	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	434	145	A	E	gCa/gAa	4,21	1	0	possibly_damaging	0,74	deleterious	0	neutral	4,23	deleterious	-3,91	deleterious	-3,86	high_impact	4,46	damaging	0,53	neutral	0,38	deleterious	2,76	21,1	0,02	0,35	NA	NA	disease	0,88	disease	0,77	disease	0,8	6	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,63	low_impact	-1,14	low_impact	-1,48	high_impact	3,29	0,4	0,8	46,19	9,28	P	0,69	P	0,99	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11193	11193	C	T	MI.17244	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	434	145	A	V	gCa/gTa	4,21	1	0	benign	0,03	deleterious	0	neutral	4,21	deleterious	-5,31	deleterious	-3,09	high_impact	3,66	damaging	0,41	neutral	0,43	deleterious	2,48	19,35	0,05	0,35	NA	NA	disease	0,82	disease	0,7	disease	0,75	5	deleterious	1	deleterious	0,49	deleterious	2	neutral	0,29	medium_impact	0,7	low_impact	-1,48	high_impact	2,5	0,69	0,85	46,19	9,28	P	0,71	P	0,72	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11193	11193	C	G	MI.17245	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	434	145	A	G	gCa/gGa	4,21	1	0	possibly_damaging	0,51	deleterious	0	neutral	4,23	deleterious	-4,03	deleterious	-3,09	high_impact	3,92	damaging	0,47	neutral	0,5	deleterious	2,07	16,66	0,07	0,35	NA	NA	disease	0,74	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,25	deleterious	5	deleterious	0,44	medium_impact	-0,73	low_impact	-1,48	high_impact	2,75	0,71	0,85	46,19	9,28	P	0,67	P	0,79	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11195	11195	G	A	MI.17246	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	436	146	G	S	Ggc/Agc	-8,24	0	0	benign	0,24	neutral	0,26	neutral	4,76	neutral	-1,14	deleterious	-4,47	low_impact	1,47	neutral	0,62	neutral	0,58	deleterious	4,08	23,7	0,06	0,35	NA	NA	disease	0,85	neutral	0,47	neutral	0,49	0	neutral	0,69	deleterious	0,51	neutral	-6	deleterious	0,89	medium_impact	-0,25	medium_impact	-0,05	medium_impact	0,33	0,65	0,8	17,86	20,57	N	0,38	N	0,39	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11195	11195	G	T	MI.17247	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	436	146	G	C	Ggc/Tgc	-8,24	0	0	probably_damaging	0,99	deleterious	0,03	neutral	4,44	deleterious	-4,06	deleterious	-6,82	medium_impact	3,36	damaging	0,57	damaging	0,27	deleterious	4,09	23,7	0,02	0,35	NA	NA	disease	0,93	disease	0,67	disease	0,79	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,92	low_impact	-2,59	medium_impact	-0,64	high_impact	2,2	0,25	0,8	17,86	20,57	N	0,3	N	0,87	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11195	11195	G	C	MI.17248	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	436	146	G	R	Ggc/Cgc	-8,24	0	0	probably_damaging	0,97	deleterious	0	neutral	4,43	neutral	-2,83	deleterious	-6,06	high_impact	4,16	damaging	0,58	neutral	0,29	deleterious	3,91	23,5	0,03	0,35	NA	NA	disease	0,92	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,94	low_impact	-2,14	low_impact	-1,48	high_impact	2,99	0,5	0,8	17,86	20,57	N	0,43	N	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11196	11196	G	T	MI.17249	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	437	146	G	V	gGc/gTc	5,13	1	0	probably_damaging	0,97	deleterious	0,03	neutral	4,49	neutral	-1,85	deleterious	-6,83	medium_impact	3,19	damaging	0,57	neutral	0,35	deleterious	3,71	23,3	0,03	0,35	NA	NA	disease	0,91	disease	0,67	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,91	low_impact	-2,14	medium_impact	-0,64	high_impact	2,03	0,26	0,8	17,86	20,57	P	0,55	P	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8499	8499	A	T	MI.1725	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	134	45	K	M	aAa/aTa	-7,28	0	0	probably_damaging	0,98	neutral	0,23	neutral	1,45	deleterious	-3,74	neutral	-1,24	low_impact	1,43	neutral	1	neutral	0,83	deleterious	2,44	19,07	0,44957237	0,85	neutral	0,38	neutral	0,08	neutral	0,27	neutral	0,04	9	deleterious	0,99	neutral	0,13	neutral	-2	deleterious	0,67	low_impact	-2,36	medium_impact	-0,01	medium_impact	0,13	0,63	0,85	20,59	9,8	P	0,58	P	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11196	11196	G	C	MI.17250	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	437	146	G	A	gGc/gCc	5,13	1	0	possibly_damaging	0,78	neutral	0,12	neutral	4,66	neutral	1,19	deleterious	-4,52	low_impact	1,88	neutral	0,63	neutral	0,44	deleterious	3,07	22,4	0,11	0,4	NA	NA	disease	0,81	disease	0,6	disease	0,69	4	neutral	0,92	neutral	0,17	neutral	-3	deleterious	0,88	low_impact	-1,23	medium_impact	-0,28	medium_impact	0,73	0,28	0,8	17,86	20,57	P	0,59	P	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11196	11196	G	A	MI.17251	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	437	146	G	D	gGc/gAc	5,13	1	0	probably_damaging	0,91	deleterious	0	neutral	4,42	deleterious	-3,91	deleterious	-5,29	high_impact	3,82	neutral	0,62	neutral	0,32	deleterious	3,79	23,4	0,02	0,35	NA	NA	disease	0,91	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,91	low_impact	-1,66	low_impact	-1,48	high_impact	2,65	0,21	0,8	17,86	20,57	P	0,56	P	0,91	polymorphism	1	0,31	.	.	.	.	.	.	COSM488729	.	.	.	.	.	.	.	.
chrM	11198	11198	A	C	MI.17252	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	439	147	T	P	Aca/Cca	-13,54	0	0	possibly_damaging	0,72	neutral	0,19	neutral	4,56	neutral	-2,73	deleterious	-2,67	medium_impact	2,74	neutral	0,67	neutral	0,4	deleterious	0,64	8,43	0,04	0,35	NA	NA	disease	0,84	disease	0,69	disease	0,77	5	neutral	0,85	neutral	0,24	NA	0	deleterious	0,57	low_impact	-1,1	medium_impact	-0,15	medium_impact	1,59	0,34	0,8	30,28	28,04	N	0,35	N	0,86	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11198	11198	A	T	MI.17253	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	439	147	T	S	Aca/Tca	-13,54	0	0	benign	0,04	neutral	0,4	neutral	4,59	neutral	-1,18	neutral	-1,46	neutral_impact	0,66	neutral	0,8	neutral	0,91	deleterious	0,03	2,91	0,25	0,45	NA	NA	neutral	0,49	neutral	0,34	neutral	0,44	1	neutral	0,57	deleterious	0,68	neutral	-6	neutral	0,17	medium_impact	0,58	medium_impact	0,1	medium_impact	-0,47	0,46	0,8	30,28	28,04	N	0,33	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11198	11198	A	G	MI.17254	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	439	147	T	A	Aca/Gca	-13,54	0	0	benign	0,22	neutral	0,48	neutral	4,62	neutral	-0,48	neutral	-1,43	medium_impact	2,19	neutral	0,72	neutral	0,7	deleterious	0,23	5	0,21	0,45	NA	NA	neutral	0,49	neutral	0,44	neutral	0,4	2	neutral	0,42	deleterious	0,63	neutral	-3	neutral	0,21	medium_impact	-0,2	medium_impact	0,18	medium_impact	1,04	0,46	0,8	30,28	28,04	N	0,37	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11199	11199	C	T	MI.17255	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	440	147	T	M	aCa/aTa	-1,32	0	0	benign	0,15	neutral	0,23	neutral	4,71	neutral	0,79	neutral	-0,68	neutral_impact	0,24	neutral	0,74	neutral	0,91	deleterious	2,56	19,84	0,12	0,4	NA	NA	neutral	0,42	neutral	0,35	neutral	0,18	6	neutral	0,73	deleterious	0,54	neutral	-6	deleterious	0,63	medium_impact	-0,01	medium_impact	-0,09	medium_impact	-0,89	0,65	0,8	30,28	28,04	N	0,44	N	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11199	11199	C	A	MI.17256	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	440	147	T	K	aCa/aAa	-1,32	0	0	possibly_damaging	0,44	neutral	0,28	neutral	4,57	neutral	-2,09	neutral	-2,27	low_impact	1,36	neutral	0,69	neutral	0,48	neutral	1,47	13,18	0,05	0,35	NA	NA	disease	0,8	disease	0,59	disease	0,74	5	neutral	0,68	neutral	0,42	neutral	-3	neutral	0,34	medium_impact	-0,62	medium_impact	-0,03	medium_impact	0,22	0,61	0,8	30,28	28,04	N	0,32	N	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11201	11201	T	A	MI.17257	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	442	148	Y	N	Tac/Aac	-11,93	0	0	probably_damaging	1	deleterious	0	neutral	4,55	neutral	-1,9	deleterious	-6,95	high_impact	3,56	damaging	0,57	damaging	0,11	deleterious	4	23,6	0,09	0,35	NA	NA	disease	0,91	disease	0,72	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	2,4	0,2	0,8	47,06	9,27	N	0,33	N	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11201	11201	T	G	MI.17258	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	442	148	Y	D	Tac/Gac	-11,93	0	0	probably_damaging	1	deleterious	0	neutral	4,53	neutral	-2,08	deleterious	-7,72	high_impact	4,37	neutral	0,69	damaging	0,11	deleterious	3,94	23,5	0,03	0,35	NA	NA	disease	0,9	disease	0,76	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	3,2	0,18	0,8	47,06	9,27	N	0,52	P	0,99	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11201	11201	T	C	MI.17259	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	442	148	Y	H	Tac/Cac	-11,93	0	0	probably_damaging	1	deleterious	0,01	neutral	4,51	neutral	-2,05	deleterious	-3,86	high_impact	4,37	damaging	0,57	damaging	0,09	deleterious	3,51	23,1	0,2	0,45	NA	NA	disease	0,86	disease	0,75	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,54	medium_impact	-0,92	high_impact	3,2	0,24	0,8	47,06	9,27	N	0,42	N	0,97	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8499	8499	A	C	MI.1726	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	134	45	K	T	aAa/aCa	-7,28	0	0	probably_damaging	0,92	neutral	0,47	neutral	1,52	neutral	-0,93	neutral	-1,28	neutral_impact	0,59	neutral	1	neutral	0,86	neutral	1,4	12,8	0,56962521	0,85	neutral	0,22	neutral	0,22	neutral	0,25	neutral	0,19	6	neutral	0,91	neutral	0,28	neutral	-2	deleterious	0,65	low_impact	-1,76	medium_impact	0,26	medium_impact	-0,59	0,67	0,85	20,59	9,8	N	0,47	N	0,05	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11202	11202	A	G	MI.17260	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	443	148	Y	C	tAc/tGc	5,83	1	0	probably_damaging	1	deleterious	0,01	neutral	4,5	deleterious	-4,8	deleterious	-6,95	high_impact	4,02	damaging	0,6	damaging	0,1	deleterious	3,31	22,9	0,05	0,35	NA	NA	disease	0,91	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-3,54	medium_impact	-0,92	high_impact	2,85	0,1	0,8	47,06	9,27	P	0,57	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11202	11202	A	C	MI.17261	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	443	148	Y	S	tAc/tCc	5,83	1	0	probably_damaging	1	deleterious	0,01	neutral	4,57	neutral	-1,56	deleterious	-6,95	medium_impact	3,4	neutral	0,61	damaging	0,13	deleterious	3,51	23,1	0,07	0,35	NA	NA	disease	0,89	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,88	low_impact	-3,54	medium_impact	-0,92	high_impact	2,24	0,19	0,8	47,06	9,27	P	0,58	P	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11202	11202	A	T	MI.17262	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	443	148	Y	F	tAc/tTc	5,83	1	0	probably_damaging	1	deleterious	0,03	neutral	4,56	neutral	-2,78	deleterious	-3,09	medium_impact	2,92	damaging	0,57	damaging	0,13	deleterious	3,18	22,7	0,28	0,45	NA	NA	disease	0,86	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,87	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,76	0,41	0,8	47,06	9,27	P	0,54	P	0,79	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11204	11204	T	A	MI.17263	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	445	149	F	I	Ttc/Atc	-1,09	0	0,02	benign	0,38	deleterious	0,01	neutral	4,59	neutral	-2,46	deleterious	-4,62	medium_impact	2,67	neutral	0,72	neutral	0,65	deleterious	2,6	20,2	0,1	0,4	NA	NA	disease	0,83	disease	0,61	disease	0,71	4	deleterious	0,99	neutral	0,32	deleterious	1	neutral	0,26	medium_impact	-0,52	medium_impact	-0,92	medium_impact	1,52	0,51	0,8	46,19	9,05	N	0,37	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11204	11204	T	C	MI.17264	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	445	149	F	L	Ttc/Ctc	-1,09	0	0,02	benign	0,03	neutral	0,68	neutral	4,76	neutral	-1,75	deleterious	-4,62	low_impact	1,15	neutral	0,71	neutral	0,65	deleterious	2,16	17,25	0,19	0,45	NA	NA	disease	0,57	neutral	0,49	neutral	0,44	1	neutral	0,27	deleterious	0,83	neutral	-6	neutral	0,17	medium_impact	0,7	medium_impact	0,39	medium_impact	0,01	0,74	0,85	46,19	9,05	N	0,29	N	0,92	polymorphism	1	0,09	rs201803443	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11204	11204	T	G	MI.17265	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	445	149	F	V	Ttc/Gtc	-1,09	0	0,02	possibly_damaging	0,52	deleterious	0,01	neutral	4,6	neutral	-2,31	deleterious	-5,4	high_impact	3,51	neutral	0,7	neutral	0,56	deleterious	2,24	17,76	0,06	0,35	NA	NA	disease	0,88	disease	0,67	disease	0,76	5	deleterious	0,99	neutral	0,25	deleterious	5	neutral	0,28	medium_impact	-0,75	medium_impact	-0,92	high_impact	2,35	0,42	0,8	46,19	9,05	N	0,39	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11205	11205	T	A	MI.17266	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	446	149	F	Y	tTc/tAc	3,06	0,99	0	possibly_damaging	0,74	deleterious	0	neutral	4,87	neutral	-0,02	neutral	-2,31	medium_impact	3,37	neutral	0,72	neutral	0,53	deleterious	2,43	18,98	0,13	0,4	NA	NA	disease	0,82	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,13	deleterious	4	neutral	0,38	low_impact	-1,14	low_impact	-1,48	high_impact	2,21	0,66	0,8	46,19	9,05	P	0,59	P	0,88	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11205	11205	T	G	MI.17267	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	446	149	F	C	tTc/tGc	3,06	0,99	0	probably_damaging	0,96	deleterious	0	neutral	4,52	deleterious	-5,03	deleterious	-6,17	high_impact	4,06	neutral	0,73	neutral	0,52	deleterious	3,86	23,5	0,03	0,35	NA	NA	disease	0,91	disease	0,68	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,75	low_impact	-2,01	low_impact	-1,48	high_impact	2,89	0,34	0,8	46,19	9,05	P	0,53	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11205	11205	T	C	MI.17268	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	446	149	F	S	tTc/tCc	3,06	0,99	0	possibly_damaging	0,89	deleterious	0	neutral	4,55	neutral	-2,63	deleterious	-6,17	high_impact	3,71	neutral	0,73	neutral	0,6	deleterious	2,54	19,73	0,02	0,35	NA	NA	disease	0,88	disease	0,66	disease	0,76	5	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,44	low_impact	-1,57	low_impact	-1,48	high_impact	2,54	0,43	0,8	46,19	9,05	P	0,56	P	0,93	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11206	11206	C	A	MI.17269	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	447	149	F	L	ttC/ttA	7,44	1	0	benign	0,03	neutral	0,68	neutral	4,76	neutral	-1,75	deleterious	-4,62	low_impact	1,15	neutral	0,71	neutral	0,65	deleterious	2,69	20,7	0,19	0,45	NA	NA	disease	0,57	neutral	0,49	neutral	0,44	1	neutral	0,27	deleterious	0,83	neutral	-6	neutral	0,17	medium_impact	0,7	medium_impact	0,39	medium_impact	0,01	0,74	0,85	46,19	9,05	N	0,51	P	0,92	polymorphism	1	0,09	rs28756874	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8500	8500	A	C	MI.1727	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	135	45	K	N	aaA/aaC	-6,35	0	0	probably_damaging	0,95	neutral	0,37	neutral	1,51	neutral	-1,11	neutral	-1,33	low_impact	1,78	neutral	0,99	neutral	0,8	neutral	1,8	14,97	0,78510221	0,85	neutral	0,27	neutral	0,19	neutral	0,36	neutral	0,11	8	neutral	0,95	neutral	0,21	neutral	-2	deleterious	0,66	low_impact	-1,97	medium_impact	0,16	medium_impact	0,43	0,79	0,85	20,59	9,8	N	0,49	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11206	11206	C	G	MI.17270	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	447	149	F	L	ttC/ttG	7,44	1	0	benign	0,03	neutral	0,68	neutral	4,76	neutral	-1,75	deleterious	-4,62	low_impact	1,15	neutral	0,71	neutral	0,65	deleterious	2,36	18,54	0,19	0,45	NA	NA	disease	0,57	neutral	0,49	neutral	0,44	1	neutral	0,27	deleterious	0,83	neutral	-6	neutral	0,17	medium_impact	0,7	medium_impact	0,39	medium_impact	0,01	0,74	0,85	46,19	9,05	N	0,53	P	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11207	11207	C	G	MI.17271	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	448	150	L	V	Cta/Gta	-4,78	0	0,01	probably_damaging	1	neutral	0,11	neutral	4,59	neutral	-1,15	neutral	-2,31	medium_impact	2,29	neutral	0,64	damaging	0,12	deleterious	3,34	22,9	0,17	0,45	NA	NA	disease	0,61	disease	0,62	disease	0,59	2	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,31	medium_impact	1,14	0,52	0,8	46,84	9,18	N	0,29	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11207	11207	C	A	MI.17272	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	448	150	L	M	Cta/Ata	-4,78	0	0,01	probably_damaging	1	neutral	0,3	neutral	4,51	neutral	-2,43	neutral	-1,54	low_impact	1,52	neutral	0,75	neutral	0,28	deleterious	3,64	23,2	0,16	0,45	NA	NA	neutral	0,35	neutral	0,4	neutral	0,16	7	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,73	low_impact	-3,54	medium_impact	0	medium_impact	0,38	0,4	0,8	46,84	9,18	N	0,35	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11208	11208	T	A	MI.17273	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	449	150	L	Q	cTa/cAa	-2,01	0	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-5,08	deleterious	-4,63	high_impact	4,04	neutral	0,61	damaging	0,11	deleterious	4,01	23,6	0,01	0,35	NA	NA	disease	0,82	disease	0,63	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,87	0,33	0,8	46,84	9,18	N	0,35	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11208	11208	T	G	MI.17274	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	449	150	L	R	cTa/cGa	-2,01	0	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-4,89	deleterious	-4,63	high_impact	4,04	neutral	0,61	damaging	0,1	deleterious	4,13	23,8	0,01	0,35	NA	NA	disease	0,89	disease	0,74	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	2,87	0,2	0,8	46,84	9,18	N	0,37	N	1	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11208	11208	T	C	MI.17275	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	449	150	L	P	cTa/cCa	-2,01	0	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-5,46	deleterious	-5,4	high_impact	4,04	damaging	0,57	damaging	0,1	deleterious	3,85	23,4	0,01	0,35	NA	NA	disease	0,85	disease	0,74	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	2,87	0,45	0,8	46,84	9,18	N	0,35	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11210	11210	T	C	MI.17276	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	451	151	F	L	Ttc/Ctc	-0,86	0,01	0	benign	0,08	neutral	0,16	neutral	5,08	neutral	2,14	deleterious	-4,62	low_impact	1,64	neutral	0,66	neutral	0,3	deleterious	3,93	23,5	0,21	0,45	NA	NA	disease	0,81	disease	0,53	neutral	0,49	0	neutral	0,82	deleterious	0,54	neutral	-6	deleterious	0,79	medium_impact	0,28	medium_impact	-0,2	medium_impact	0,5	0,64	0,8	47,28	9,39	N	0,27	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11210	11210	T	G	MI.17277	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	451	151	F	V	Ttc/Gtc	-0,86	0,01	0	possibly_damaging	0,74	deleterious	0,02	neutral	4,68	neutral	0,31	deleterious	-5,39	medium_impact	2,68	neutral	0,72	damaging	0,15	deleterious	3,97	23,6	0,11	0,4	NA	NA	disease	0,89	disease	0,67	disease	0,75	5	deleterious	0,98	neutral	0,14	deleterious	4	deleterious	0,83	low_impact	-1,14	medium_impact	-0,75	medium_impact	1,53	0,42	0,8	47,28	9,39	N	0,33	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11210	11210	T	A	MI.17278	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	451	151	F	I	Ttc/Atc	-0,86	0,01	0	possibly_damaging	0,74	neutral	0,05	neutral	4,66	neutral	0,12	deleterious	-4,62	medium_impact	2,04	neutral	0,72	damaging	0,16	deleterious	4,32	24	0,14	0,4	NA	NA	disease	0,81	disease	0,61	disease	0,53	1	neutral	0,96	neutral	0,16	NA	0	deleterious	0,82	low_impact	-1,14	medium_impact	-0,52	medium_impact	0,89	0,46	0,8	47,28	9,39	N	0,37	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11211	11211	T	G	MI.17279	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	452	151	F	C	tTc/tGc	7,44	1	0	probably_damaging	0,98	deleterious	0,01	neutral	4,5	deleterious	-3,34	deleterious	-6,16	high_impact	4,16	neutral	0,73	damaging	0,12	deleterious	4,01	23,6	0,03	0,35	NA	NA	disease	0,9	disease	0,66	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,85	low_impact	-2,31	medium_impact	-0,92	high_impact	2,99	0,3	0,8	47,28	9,39	P	0,58	P	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8500	8500	A	T	MI.1728	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	135	45	K	N	aaA/aaT	-6,35	0	0	probably_damaging	0,95	neutral	0,37	neutral	1,51	neutral	-1,11	neutral	-1,33	low_impact	1,78	neutral	0,99	neutral	0,8	deleterious	1,88	15,44	0,78510221	0,85	neutral	0,27	neutral	0,19	neutral	0,36	neutral	0,11	8	neutral	0,95	neutral	0,21	neutral	-2	deleterious	0,66	low_impact	-1,97	medium_impact	0,16	medium_impact	0,43	0,79	0,85	20,59	9,8	N	0,49	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11211	11211	T	A	MI.17280	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	452	151	F	Y	tTc/tAc	7,44	1	0	possibly_damaging	0,89	deleterious	0	neutral	4,51	neutral	-2,55	neutral	-2,31	high_impact	3,81	neutral	0,73	damaging	0,13	deleterious	4,37	24,1	0,13	0,4	NA	NA	disease	0,83	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,83	low_impact	-1,57	low_impact	-1,48	high_impact	2,64	0,5	0,8	47,28	9,39	P	0,63	P	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11211	11211	T	C	MI.17281	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	452	151	F	S	tTc/tCc	7,44	1	0	probably_damaging	0,96	deleterious	0	neutral	4,56	neutral	-1,22	deleterious	-6,16	high_impact	3,81	neutral	0,73	damaging	0,16	deleterious	4,24	23,9	0,04	0,35	NA	NA	disease	0,88	disease	0,64	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-2,01	low_impact	-1,48	high_impact	2,64	0,46	0,8	47,28	9,39	P	0,62	P	0,93	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11212	11212	C	A	MI.17282	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	453	151	F	L	ttC/ttA	7,44	1	0	benign	0,08	neutral	0,16	neutral	5,08	neutral	2,14	deleterious	-4,62	low_impact	1,64	neutral	0,66	neutral	0,3	deleterious	4,48	24,2	0,21	0,45	NA	NA	disease	0,81	disease	0,53	neutral	0,49	0	neutral	0,82	deleterious	0,54	neutral	-6	deleterious	0,79	medium_impact	0,28	medium_impact	-0,2	medium_impact	0,5	0,64	0,8	47,28	9,39	P	0,59	P	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11212	11212	C	G	MI.17283	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	453	151	F	L	ttC/ttG	7,44	1	0	benign	0,08	neutral	0,16	neutral	5,08	neutral	2,14	deleterious	-4,62	low_impact	1,64	neutral	0,66	neutral	0,3	deleterious	4,26	23,9	0,21	0,45	NA	NA	disease	0,81	disease	0,53	neutral	0,49	0	neutral	0,82	deleterious	0,54	neutral	-6	deleterious	0,79	medium_impact	0,28	medium_impact	-0,2	medium_impact	0,5	0,64	0,8	47,28	9,39	P	0,58	P	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11213	11213	T	G	MI.17284	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	454	152	Y	D	Tac/Gac	-4,09	0	0	probably_damaging	1	deleterious	0	neutral	4,44	deleterious	-4,97	deleterious	-7,72	high_impact	4,53	neutral	0,67	damaging	0,12	deleterious	3,8	23,4	0,02	0,35	NA	NA	disease	0,9	disease	0,81	disease	0,81	6	deleterious	1	deleterious	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,36	0,36	0,8	47,06	9,31	N	0,54	P	0,99	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11213	11213	T	A	MI.17285	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	454	152	Y	N	Tac/Aac	-4,09	0	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-4,42	deleterious	-6,95	high_impact	4,53	neutral	0,63	damaging	0,11	deleterious	3,89	23,5	0,03	0,35	NA	NA	disease	0,9	disease	0,74	disease	0,79	6	deleterious	1	deleterious	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,36	0,44	0,8	47,06	9,31	N	0,46	N	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11213	11213	T	C	MI.17286	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	454	152	Y	H	Tac/Cac	-4,09	0	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-4,7	deleterious	-3,86	high_impact	4,53	neutral	0,61	damaging	0,1	deleterious	3,45	23	0,09	0,35	NA	NA	disease	0,87	disease	0,8	disease	0,8	6	deleterious	1	deleterious	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,36	0,42	0,8	47,06	9,31	P	0,57	P	0,97	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11214	11214	A	G	MI.17287	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	455	152	Y	C	tAc/tGc	5,6	1	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-3,66	deleterious	-6,95	high_impact	4,53	neutral	0,65	damaging	0,08	deleterious	3,46	23	0,03	0,35	NA	NA	disease	0,9	disease	0,77	disease	0,8	6	deleterious	1	deleterious	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,36	0,26	0,8	47,06	9,31	P	0,66	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11214	11214	A	T	MI.17288	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	455	152	Y	F	tAc/tTc	5,6	1	0	probably_damaging	1	deleterious	0,04	neutral	4,48	neutral	-1,91	deleterious	-3,09	medium_impact	2,98	neutral	0,64	damaging	0,12	deleterious	3,42	23	0,18	0,45	NA	NA	disease	0,86	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,85	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,82	0,66	0,8	47,06	9,31	P	0,57	P	0,79	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11214	11214	A	C	MI.17289	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	455	152	Y	S	tAc/tCc	5,6	1	0	probably_damaging	1	deleterious	0	neutral	4,49	neutral	-2,84	deleterious	-6,95	high_impact	4,53	neutral	0,65	damaging	0,12	deleterious	3,63	23,2	0,03	0,35	NA	NA	disease	0,88	disease	0,71	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,36	0,47	0,8	47,06	9,31	P	0,62	P	0,95	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8501	8501	A	G	MI.1729	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	136	46	N	D	Aat/Gat	-6,35	0	0	possibly_damaging	0,87	neutral	0,27	neutral	1,79	neutral	-0,67	neutral	-1,31	low_impact	0,98	neutral	1	neutral	0,54	neutral	1,58	13,74	0,76071314	0,85	neutral	0,27	neutral	0,08	neutral	0,32	neutral	0,05	9	neutral	0,9	neutral	0,2	neutral	-3	deleterious	0,6	low_impact	-1,54	medium_impact	0,05	medium_impact	-0,26	0,68	0,85	NA	NA	N	0,53	P	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11216	11216	A	T	MI.17290	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	457	153	T	S	Acc/Tcc	-3,17	0	0	probably_damaging	1	deleterious	0	neutral	4,56	neutral	-1,76	deleterious	-3,09	high_impact	3,55	neutral	0,61	damaging	0,15	deleterious	3,13	22,6	0,29	0,45	NA	NA	disease	0,76	disease	0,66	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,39	0,73	0,85	47,49	9,33	N	0,37	N	0,87	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11216	11216	A	C	MI.17291	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	457	153	T	P	Acc/Ccc	-3,17	0	0	probably_damaging	1	deleterious	0	neutral	4,42	deleterious	-4,93	deleterious	-4,63	high_impact	4,53	damaging	0,59	damaging	0,12	deleterious	3,36	22,9	0,04	0,35	NA	NA	disease	0,85	disease	0,79	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	3,36	0,45	0,8	47,49	9,33	N	0,53	P	0,97	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11216	11216	A	G	MI.17292	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	457	153	T	A	Acc/Gcc	-3,17	0	0	probably_damaging	1	deleterious	0,04	neutral	4,5	neutral	-1,43	deleterious	-3,86	high_impact	3,72	damaging	0,58	damaging	0,17	deleterious	3,3	22,9	0,12	0,4	NA	NA	disease	0,7	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,81	low_impact	-3,54	medium_impact	-0,57	high_impact	2,55	0,33	0,8	47,49	9,33	N	0,31	N	0,69	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11217	11217	C	G	MI.17293	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	458	153	T	S	aCc/aGc	4,67	1	0	probably_damaging	1	deleterious	0	neutral	4,56	neutral	-1,76	deleterious	-3,09	high_impact	3,55	neutral	0,61	damaging	0,15	deleterious	3,47	23	0,29	0,45	NA	NA	disease	0,76	disease	0,66	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,39	0,73	0,85	47,49	9,33	P	0,55	P	0,87	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11217	11217	C	T	MI.17294	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	458	153	T	I	aCc/aTc	4,67	1	0	probably_damaging	1	deleterious	0,02	neutral	4,42	deleterious	-3,32	deleterious	-4,63	high_impact	3,98	damaging	0,58	damaging	0,13	deleterious	3,92	23,5	0,06	0,35	NA	NA	disease	0,88	disease	0,67	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,54	medium_impact	-0,75	high_impact	2,81	0,62	0,8	47,49	9,33	P	0,54	P	0,95	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11217	11217	C	A	MI.17295	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	458	153	T	N	aCc/aAc	4,67	1	0	probably_damaging	1	deleterious	0	neutral	4,6	neutral	-0,5	deleterious	-3,86	high_impact	3,98	damaging	0,55	damaging	0,14	deleterious	3,6	23,2	0,2	0,45	NA	NA	disease	0,87	disease	0,68	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,81	0,54	0,8	47,49	9,33	P	0,56	P	0,93	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11219	11219	C	A	MI.17296	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	460	154	L	M	Cta/Ata	-13,31	0	0	probably_damaging	1	neutral	0,07	neutral	4,56	neutral	-2,73	neutral	-1,53	medium_impact	2,09	damaging	0,59	damaging	0,21	deleterious	3,68	23,3	0,28	0,45	NA	NA	disease	0,53	neutral	0,41	neutral	0,45	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	-0,43	medium_impact	0,94	0,68	0,85	46,84	9,05	N	0,34	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11219	11219	C	G	MI.17297	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	460	154	L	V	Cta/Gta	-13,31	0	0	probably_damaging	1	neutral	0,17	neutral	4,62	neutral	-1,36	neutral	-2,29	medium_impact	2,07	damaging	0,57	damaging	0,11	deleterious	3,36	22,9	0,26	0,45	NA	NA	disease	0,59	disease	0,56	neutral	0,48	0	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,18	medium_impact	0,92	0,61	0,8	46,84	9,05	N	0,28	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11220	11220	T	G	MI.17298	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	461	154	L	R	cTa/cGa	-1,55	0	0	probably_damaging	1	deleterious	0	neutral	4,71	neutral	-0,78	deleterious	-4,62	high_impact	3,9	damaging	0,57	damaging	0,09	deleterious	4,1	23,7	0,05	0,35	NA	NA	disease	0,9	disease	0,74	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	2,73	0,18	0,8	46,84	9,05	N	0,35	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11220	11220	T	C	MI.17299	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	461	154	L	P	cTa/cCa	-1,55	0	0	probably_damaging	1	deleterious	0,01	neutral	4,53	deleterious	-5,06	deleterious	-5,38	high_impact	4,25	damaging	0,53	damaging	0,11	deleterious	3,83	23,4	0,04	0,35	NA	NA	disease	0,82	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-3,54	medium_impact	-0,92	high_impact	3,08	0,25	0,8	46,84	9,05	N	0,39	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8606	8606	C	T	MI.173	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	80	27	P	L	cCc/cTc	5,45	1	0	probably_damaging	1	neutral	0,67	neutral	4,57	neutral	1,84	deleterious	-8,3	medium_impact	2,47	neutral	0,65	neutral	0,49	deleterious	4,22	23,9	0,4	0,65	neutral	0,27	disease	0,84	disease	0,54	disease	0,67	3	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,47	medium_impact	1,02	0,81	0,9	48,23	8,81	N	0,43	N	0,97	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8501	8501	A	T	MI.1730	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	136	46	N	Y	Aat/Tat	-6,35	0	0	probably_damaging	0,98	neutral	0,1	neutral	1,5	deleterious	-3,03	neutral	-2,36	low_impact	1,45	neutral	0,99	neutral	0,71	deleterious	3,45	23	0,61638548	0,85	disease	0,61	neutral	0,12	neutral	0,24	neutral	0,1	8	deleterious	0,99	neutral	0,06	neutral	-2	deleterious	0,68	low_impact	-2,36	medium_impact	-0,25	medium_impact	0,15	0,7	0,85	NA	NA	P	0,56	P	0,38	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11220	11220	T	A	MI.17300	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	461	154	L	Q	cTa/cAa	-1,55	0	0	probably_damaging	1	deleterious	0	neutral	4,58	deleterious	-3,2	deleterious	-4,62	medium_impact	3,21	damaging	0,54	damaging	0,1	deleterious	3,99	23,6	0,06	0,35	NA	NA	disease	0,8	disease	0,64	disease	0,7	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,05	0,25	0,8	46,84	9,05	N	0,29	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11222	11222	G	T	MI.17301	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	463	155	V	L	Gta/Tta	-0,63	0	0	benign	0,02	neutral	0,84	neutral	4,69	neutral	-0,67	neutral	-0,47	neutral_impact	0,7	neutral	0,76	neutral	0,86	deleterious	2,35	18,49	0,23	0,45	NA	NA	neutral	0,48	neutral	0,3	neutral	0,3	4	neutral	0,11	deleterious	0,91	neutral	-6	deleterious	0,69	medium_impact	0,87	medium_impact	0,61	medium_impact	-0,43	0,38	0,8	11,11	10,8	N	0,25	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11222	11222	G	C	MI.17302	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	463	155	V	L	Gta/Cta	-0,63	0	0	benign	0,02	neutral	0,84	neutral	4,69	neutral	-0,67	neutral	-0,47	neutral_impact	0,7	neutral	0,76	neutral	0,86	deleterious	2,19	17,44	0,23	0,45	NA	NA	neutral	0,48	neutral	0,3	neutral	0,3	4	neutral	0,11	deleterious	0,91	neutral	-6	deleterious	0,69	medium_impact	0,87	medium_impact	0,61	medium_impact	-0,43	0,38	0,8	11,11	10,8	N	0,25	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11222	11222	G	A	MI.17303	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	463	155	V	M	Gta/Ata	-0,63	0	0	possibly_damaging	0,76	neutral	0,26	neutral	4,47	deleterious	-3,44	neutral	-0,34	neutral_impact	0,8	neutral	0,72	neutral	0,94	deleterious	2,27	17,95	0,2	0,45	NA	NA	neutral	0,35	neutral	0,33	neutral	0,14	7	neutral	0,83	neutral	0,25	neutral	-3	deleterious	0,67	low_impact	-1,19	medium_impact	-0,05	medium_impact	-0,33	0,54	0,8	11,11	10,8	N	0,46	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11223	11223	T	G	MI.17304	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	464	155	V	G	gTa/gGa	-2,71	0	0	benign	0,27	neutral	0,34	neutral	4,46	neutral	-2,85	deleterious	-2,81	low_impact	1,24	neutral	0,72	neutral	0,48	deleterious	3,77	23,4	0,05	0,35	NA	NA	disease	0,6	disease	0,59	disease	0,73	5	neutral	0,59	deleterious	0,54	neutral	-6	deleterious	0,73	medium_impact	-0,31	medium_impact	0,04	medium_impact	0,1	0,22	0,8	11,11	10,8	N	0,31	N	0,74	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11223	11223	T	C	MI.17305	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	464	155	V	A	gTa/gCa	-2,71	0	0	benign	0,01	neutral	0,59	neutral	4,53	neutral	-1,11	neutral	-0,53	neutral_impact	-0,12	neutral	0,69	neutral	0,99	deleterious	0,8	9,45	0,16	0,45	NA	NA	neutral	0,08	neutral	0,32	neutral	0,2	6	neutral	0,39	deleterious	0,79	neutral	-6	deleterious	0,65	medium_impact	1,16	medium_impact	0,29	low_impact	-1,25	0,11	0,8	11,11	10,8	N	0,4	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11223	11223	T	A	MI.17306	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	464	155	V	E	gTa/gAa	-2,71	0	0	benign	0,37	neutral	0,27	neutral	4,43	deleterious	-5,12	neutral	-2,46	medium_impact	2,9	neutral	0,69	neutral	0,45	deleterious	4,84	24,8	0,02	0,35	NA	NA	disease	0,81	disease	0,62	disease	0,8	6	neutral	0,68	neutral	0,45	neutral	-3	deleterious	0,79	medium_impact	-0,5	medium_impact	-0,04	medium_impact	1,74	0,14	0,8	11,11	10,8	N	0,36	N	0,86	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11225	11225	G	C	MI.17307	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	466	156	G	R	Ggc/Cgc	-3,17	0	0	probably_damaging	1	deleterious	0,02	neutral	4,06	deleterious	-7,56	deleterious	-5,9	high_impact	3,85	neutral	0,68	damaging	0,07	deleterious	3,83	23,4	0,02	0,35	NA	NA	disease	0,93	disease	0,8	disease	0,89	8	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,91	low_impact	-3,54	medium_impact	-0,75	high_impact	2,68	0,6	0,8	47,06	9,09	N	0,38	N	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11225	11225	G	A	MI.17308	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	466	156	G	S	Ggc/Agc	-3,17	0	0	probably_damaging	1	neutral	0,42	neutral	4,49	deleterious	-3,23	deleterious	-4,35	low_impact	0,82	neutral	0,7	neutral	0,31	deleterious	4,1	23,7	0,04	0,35	NA	NA	disease	0,54	neutral	0,46	neutral	0,46	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,78	low_impact	-3,54	medium_impact	0,12	medium_impact	-0,32	0,51	0,8	47,06	9,09	N	0,33	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11225	11225	G	T	MI.17309	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	466	156	G	C	Ggc/Tgc	-3,17	0	0	probably_damaging	1	neutral	0,17	neutral	4,08	deleterious	-7,98	deleterious	-6,6	medium_impact	3,15	neutral	0,74	damaging	0,08	deleterious	4,02	23,6	0,02	0,35	NA	NA	disease	0,91	disease	0,69	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,18	medium_impact	1,99	0,23	0,8	47,06	9,09	N	0,28	N	0,98	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8501	8501	A	C	MI.1731	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	136	46	N	H	Aat/Cat	-6,35	0	0	probably_damaging	0,98	neutral	0,16	neutral	1,52	neutral	-2,08	neutral	-1,5	low_impact	0,82	neutral	1	neutral	0,59	neutral	1,75	14,72	0,7567226	0,85	neutral	0,47	neutral	0,07	neutral	0,24	neutral	0,05	9	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,64	low_impact	-2,36	medium_impact	-0,12	medium_impact	-0,4	0,76	0,85	NA	NA	P	0,57	P	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11226	11226	G	T	MI.17310	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	467	156	G	V	gGc/gTc	5,83	1	0	probably_damaging	1	neutral	0,13	neutral	4,07	deleterious	-6,68	deleterious	-6,6	medium_impact	2,6	neutral	0,67	damaging	0,08	deleterious	3,67	23,3	0,02	0,35	NA	NA	disease	0,87	disease	0,7	disease	0,6	2	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,87	low_impact	-3,54	medium_impact	-0,26	medium_impact	1,45	0,18	0,8	47,06	9,09	N	0,45	N	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11226	11226	G	A	MI.17311	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	467	156	G	D	gGc/gAc	5,83	1	0	probably_damaging	1	deleterious	0,02	neutral	4,05	deleterious	-7,62	deleterious	-5,2	high_impact	3,85	neutral	0,7	damaging	0,08	deleterious	3,78	23,4	0,01	0,35	NA	NA	disease	0,91	disease	0,79	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,54	medium_impact	-0,75	high_impact	2,68	0,1	0,8	47,06	9,09	P	0,55	P	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11226	11226	G	C	MI.17312	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	467	156	G	A	gGc/gCc	5,83	1	0	probably_damaging	1	neutral	0,63	neutral	4,26	deleterious	-3,17	deleterious	-4,25	low_impact	0,88	neutral	0,71	damaging	0,21	deleterious	3	22,2	0,06	0,35	NA	NA	neutral	0,43	neutral	0,46	neutral	0,19	6	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,77	low_impact	-3,54	medium_impact	0,33	medium_impact	-0,26	0,47	0,8	47,06	9,09	N	0,49	N	0,76	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11228	11228	T	C	MI.17313	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	469	157	S	P	Tcc/Ccc	-2,94	0	0	probably_damaging	1	deleterious	0	neutral	3,77	deleterious	-6,27	deleterious	-3,86	high_impact	4,17	damaging	0,52	neutral	0,47	deleterious	3,89	23,5	0,03	0,35	NA	NA	disease	0,85	disease	0,8	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3	0,24	0,8	47,49	9,31	N	0,52	P	0,99	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11228	11228	T	A	MI.17314	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	469	157	S	T	Tcc/Acc	-2,94	0	0	probably_damaging	1	deleterious	0,01	neutral	3,79	deleterious	-5,14	neutral	-2,32	high_impact	3,54	damaging	0,58	neutral	0,42	deleterious	3,73	23,3	0,19	0,45	NA	NA	disease	0,69	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,54	medium_impact	-0,92	high_impact	2,38	0,59	0,8	47,49	9,31	N	0,39	N	0,73	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11228	11228	T	G	MI.17315	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	469	157	S	A	Tcc/Gcc	-2,94	0	0	probably_damaging	1	deleterious	0,01	neutral	3,86	deleterious	-3,42	neutral	-2,32	medium_impact	3,48	damaging	0,53	neutral	0,72	deleterious	3,62	23,2	0,19	0,45	NA	NA	disease	0,59	disease	0,54	neutral	0,44	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,81	low_impact	-3,54	medium_impact	-0,92	high_impact	2,32	0,31	0,8	47,49	9,31	N	0,46	N	0,51	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11229	11229	C	T	MI.17316	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	470	157	S	F	tCc/tTc	7,44	1	0	probably_damaging	1	deleterious	0	neutral	3,76	deleterious	-7,72	deleterious	-4,63	high_impact	4,51	damaging	0,48	neutral	0,44	deleterious	4,2	23,9	0,05	0,35	NA	NA	disease	0,91	disease	0,72	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,34	0,1	0,8	47,49	9,31	P	0,57	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11229	11229	C	G	MI.17317	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	470	157	S	C	tCc/tGc	7,44	1	0	probably_damaging	1	deleterious	0	neutral	3,76	deleterious	-7,76	deleterious	-3,86	high_impact	4,51	damaging	0,56	neutral	0,4	deleterious	3,55	23,1	0,06	0,35	NA	NA	disease	0,82	disease	0,68	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,34	0,21	0,8	47,49	9,31	P	0,53	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11229	11229	C	A	MI.17318	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	470	157	S	Y	tCc/tAc	7,44	1	0	probably_damaging	1	deleterious	0	neutral	3,76	deleterious	-7,44	deleterious	-4,63	high_impact	4,51	damaging	0,54	neutral	0,37	deleterious	4,01	23,6	0,04	0,35	NA	NA	disease	0,88	disease	0,73	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	3,34	0,16	0,8	47,49	9,31	P	0,54	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11231	11231	C	T	MI.17319	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	472	158	L	F	Ctt/Ttt	-13,77	0	0	probably_damaging	0,98	neutral	0,12	neutral	4,53	neutral	-1,26	deleterious	-3,01	medium_impact	2,7	neutral	0,66	damaging	0,15	deleterious	3,91	23,5	0,2	0,45	NA	NA	disease	0,71	disease	0,57	disease	0,61	2	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,82	low_impact	-2,31	medium_impact	-0,28	medium_impact	1,55	0,63	0,8	18,3	22,31	N	0,23	N	0,73	polymorphism	1	0,08	rs28592011	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8502	8502	A	C	MI.1732	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	137	46	N	T	aAt/aCt	-0,1	0	0	probably_damaging	0,92	neutral	0,35	neutral	1,56	neutral	-1,24	neutral	-0,43	neutral_impact	-0,16	neutral	1	neutral	0,96	neutral	1,14	11,42	0,82750062	0,9	neutral	0,34	neutral	0,06	neutral	0,18	neutral	0,05	9	neutral	0,92	neutral	0,22	neutral	-2	deleterious	0,61	low_impact	-1,76	medium_impact	0,14	low_impact	-1,24	0,7	0,85	NA	NA	P	0,57	P	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11231	11231	C	G	MI.17320	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	472	158	L	V	Ctt/Gtt	-13,77	0	0	benign	0,3	neutral	0,08	neutral	4,6	neutral	-0,86	neutral	-2,16	medium_impact	2,57	neutral	0,64	damaging	0,26	deleterious	3,39	23	0,3	0,45	NA	NA	disease	0,56	neutral	0,42	neutral	0,45	1	neutral	0,91	neutral	0,39	neutral	-3	deleterious	0,81	medium_impact	-0,37	medium_impact	-0,39	medium_impact	1,42	0,45	0,8	18,3	22,31	N	0,37	N	0,44	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11231	11231	C	A	MI.17321	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	472	158	L	I	Ctt/Att	-13,77	0	0	possibly_damaging	0,76	neutral	0,07	neutral	4,61	neutral	-1,69	neutral	-1,39	medium_impact	2,67	neutral	0,72	neutral	0,83	deleterious	3	22,2	0,36	0,5	NA	NA	disease	0,56	neutral	0,39	neutral	0,45	1	neutral	0,95	neutral	0,16	NA	0	deleterious	0,8	low_impact	-1,19	medium_impact	-0,43	medium_impact	1,52	0,57	0,8	18,3	22,31	N	0,49	N	0,08	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11232	11232	T	C	MI.17322	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	473	158	L	P	cTt/cCt	-0,4	0	0	probably_damaging	1	deleterious	0	neutral	4,41	deleterious	-5,44	deleterious	-5,32	high_impact	4,39	damaging	0,59	damaging	0,1	deleterious	3,76	23,3	0,04	0,35	NA	NA	disease	0,81	disease	0,76	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,22	0,19	0,8	18,3	22,31	N	0,47	N	0,86	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	T11232C	CPEO	-	+	Reported	3
chrM	11232	11232	T	G	MI.17323	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	473	158	L	R	cTt/cGt	-0,4	0	0	probably_damaging	0,99	deleterious	0	neutral	4,42	deleterious	-4,87	deleterious	-4,59	high_impact	4,39	neutral	0,65	damaging	0,1	deleterious	4,14	23,8	0,04	0,35	NA	NA	disease	0,89	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-2,59	low_impact	-1,48	high_impact	3,22	0,18	0,8	18,3	22,31	N	0,52	P	0,98	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11232	11232	T	A	MI.17324	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	473	158	L	H	cTt/cAt	-0,4	0	0	probably_damaging	1	deleterious	0	neutral	4,41	deleterious	-5,39	deleterious	-5,32	high_impact	4,39	neutral	0,62	damaging	0,11	deleterious	4,01	23,6	0,06	0,35	NA	NA	disease	0,81	disease	0,72	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,22	0,22	0,8	18,3	22,31	N	0,44	N	0,82	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11234	11234	C	A	MI.17325	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	475	159	P	T	Ccc/Acc	-20	0	0	probably_damaging	1	deleterious	0	neutral	4,59	neutral	0,57	deleterious	-6,18	high_impact	4,07	damaging	0,52	damaging	0,09	deleterious	3,62	23,2	0,14	0,4	NA	NA	disease	0,81	disease	0,68	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,9	0,56	0,8	47,06	9,43	N	0,34	N	0,89	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11234	11234	C	G	MI.17326	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	475	159	P	A	Ccc/Gcc	-20	0	0	probably_damaging	1	deleterious	0	neutral	4,62	neutral	2,39	deleterious	-6,18	medium_impact	3,31	damaging	0,52	damaging	0,16	deleterious	3,03	22,3	0,14	0,4	NA	NA	disease	0,71	disease	0,65	disease	0,68	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	2,15	0,63	0,8	47,06	9,43	N	0,36	N	0,77	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11234	11234	C	T	MI.17327	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	475	159	P	S	Ccc/Tcc	-20	0	0	probably_damaging	1	deleterious	0	neutral	4,57	neutral	0,93	deleterious	-6,18	high_impact	3,86	damaging	0,5	damaging	0,11	deleterious	3,82	23,4	0,15	0,45	NA	NA	disease	0,84	disease	0,66	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,69	0,17	0,8	47,06	9,43	N	0,37	N	0,71	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11235	11235	C	T	MI.17328	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	476	159	P	L	cCc/cTc	5,6	1	0	probably_damaging	1	deleterious	0,01	neutral	4,82	neutral	3,18	deleterious	-7,72	medium_impact	2,36	damaging	0,49	damaging	0,07	deleterious	4,34	24	0,11	0,4	NA	NA	disease	0,92	disease	0,63	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,86	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,21	0,52	0,8	47,06	9,43	P	0,53	P	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11235	11235	C	A	MI.17329	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	476	159	P	H	cCc/cAc	5,6	1	0	probably_damaging	1	deleterious	0	neutral	4,54	neutral	-1,64	deleterious	-6,94	high_impact	4,41	damaging	0,51	damaging	0,08	deleterious	3,94	23,5	0,09	0,35	NA	NA	disease	0,89	disease	0,76	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	3,24	0,3	0,8	47,06	9,43	P	0,66	P	0,7	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8502	8502	A	T	MI.1733	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	137	46	N	I	aAt/aTt	-0,1	0	0	probably_damaging	0,98	neutral	0,17	neutral	1,5	neutral	-2,69	neutral	-2,46	low_impact	1,24	neutral	0,99	neutral	0,7	deleterious	2,35	18,47	0,59098804	0,85	disease	0,56	neutral	0,09	neutral	0,33	neutral	0,05	9	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,67	low_impact	-2,36	medium_impact	-0,1	medium_impact	-0,04	0,64	0,85	NA	NA	P	0,59	P	0,44	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11235	11235	C	G	MI.17330	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	476	159	P	R	cCc/cGc	5,6	1	0	probably_damaging	1	deleterious	0	neutral	4,55	neutral	-1,1	deleterious	-6,95	high_impact	4,41	damaging	0,59	damaging	0,08	deleterious	3,57	23,1	0,05	0,35	NA	NA	disease	0,92	disease	0,78	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,24	0,49	0,8	47,06	9,43	P	0,68	P	0,58	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11237	11237	C	A	MI.17331	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	478	160	L	M	Cta/Ata	-7,55	0	0	probably_damaging	1	neutral	0,26	neutral	3,78	deleterious	-3,07	neutral	-1,54	low_impact	1,38	damaging	0,5	damaging	0,1	deleterious	3,7	23,3	0,23	0,45	NA	NA	neutral	0,45	disease	0,52	neutral	0,32	4	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,77	low_impact	-3,54	medium_impact	-0,05	medium_impact	0,24	0,44	0,8	47,71	9,19	N	0,31	N	0,9	polymorphism	1	0,03	rs28546714	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11237	11237	C	G	MI.17332	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	478	160	L	V	Cta/Gta	-7,55	0	0	probably_damaging	1	deleterious	0,02	neutral	3,7	deleterious	-3,97	neutral	-2,32	medium_impact	3,23	damaging	0,41	damaging	0,07	deleterious	3,36	22,9	0,21	0,45	NA	NA	disease	0,62	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-3,54	medium_impact	-0,75	high_impact	2,07	0,41	0,8	47,71	9,19	N	0,4	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11238	11238	T	C	MI.17333	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	479	160	L	P	cTa/cCa	-0,17	0	0	probably_damaging	1	deleterious	0,03	neutral	3,61	deleterious	-8,26	deleterious	-5,41	high_impact	4,28	damaging	0,39	damaging	0,05	deleterious	3,82	23,4	0,03	0,35	NA	NA	disease	0,8	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,9	low_impact	-3,54	medium_impact	-0,64	high_impact	3,11	0,28	0,8	47,71	9,19	N	0,49	N	0,98	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11238	11238	T	G	MI.17334	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	479	160	L	R	cTa/cGa	-0,17	0	0	probably_damaging	1	deleterious	0	neutral	3,62	deleterious	-7,9	deleterious	-4,64	high_impact	4,28	damaging	0,43	damaging	0,05	deleterious	4,12	23,8	0,03	0,35	NA	NA	disease	0,88	disease	0,74	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,54	low_impact	-1,48	high_impact	3,11	0,16	0,8	47,71	9,19	N	0,47	N	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11238	11238	T	A	MI.17335	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	479	160	L	Q	cTa/cAa	-0,17	0	0	probably_damaging	1	deleterious	0	neutral	3,62	deleterious	-7,77	deleterious	-4,64	high_impact	4,28	damaging	0,41	damaging	0,05	deleterious	3,98	23,6	0,04	0,35	NA	NA	disease	0,8	disease	0,64	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,11	0,26	0,8	47,71	9,19	N	0,49	N	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11240	11240	C	T	MI.17336	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	481	161	L	F	Ctc/Ttc	-13,54	0	0	probably_damaging	1	neutral	0,09	neutral	3,59	deleterious	-3,63	deleterious	-3,09	medium_impact	2,75	damaging	0,54	damaging	0,09	deleterious	3,93	23,5	0,09	0,35	NA	NA	disease	0,67	disease	0,64	disease	0,61	2	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,36	medium_impact	1,6	0,37	0,8	47,28	9,47	N	0,26	N	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	C11240T	Leigh Syndrome	-	+	Reported	1
chrM	11240	11240	C	G	MI.17337	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	481	161	L	V	Ctc/Gtc	-13,54	0	0	probably_damaging	1	deleterious	0	neutral	3,54	deleterious	-4,28	neutral	-2,32	high_impact	4,15	damaging	0,59	damaging	0,13	deleterious	3,37	22,9	0,11	0,4	NA	NA	disease	0,56	disease	0,59	disease	0,64	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,98	0,46	0,8	47,28	9,47	N	0,37	N	0,89	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11240	11240	C	A	MI.17338	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	481	161	L	I	Ctc/Atc	-13,54	0	0	probably_damaging	1	deleterious	0,01	neutral	3,59	deleterious	-3,69	neutral	-1,54	medium_impact	3,3	damaging	0,6	damaging	0,15	deleterious	4,05	23,7	0,15	0,4	NA	NA	disease	0,55	disease	0,55	disease	0,63	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,81	low_impact	-3,54	medium_impact	-0,92	high_impact	2,14	0,38	0,8	47,28	9,47	N	0,34	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11241	11241	T	G	MI.17339	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	482	161	L	R	cTc/cGc	-3,17	0	0	probably_damaging	1	deleterious	0	neutral	3,46	deleterious	-7,78	deleterious	-4,64	high_impact	4,5	damaging	0,55	damaging	0,09	deleterious	4,11	23,7	0,02	0,35	NA	NA	disease	0,84	disease	0,76	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,13	0,8	47,28	9,47	N	0,47	N	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8502	8502	A	G	MI.1734	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	137	46	N	S	aAt/aGt	-0,1	0	0	possibly_damaging	0,87	neutral	0,41	neutral	1,59	neutral	-0,81	neutral	-0,15	neutral_impact	0,55	neutral	1	neutral	0,95	deleterious	0,64	8,42	0,88141185	0,9	neutral	0,29	neutral	0,03	neutral	0,2	neutral	0,06	9	neutral	0,87	neutral	0,27	neutral	-3	deleterious	0,59	low_impact	-1,54	medium_impact	0,2	medium_impact	-0,63	0,51	0,85	NA	NA	N	0,54	P	0,12	polymorphism	1	0,01	rs879247004	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11241	11241	T	C	MI.17340	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	482	161	L	P	cTc/cCc	-3,17	0	0	probably_damaging	1	deleterious	0	neutral	3,46	deleterious	-8,21	deleterious	-5,41	high_impact	4,15	damaging	0,54	damaging	0,09	deleterious	3,9	23,5	0,02	0,35	NA	NA	disease	0,76	disease	0,76	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	2,98	0,23	0,8	47,28	9,47	N	0,37	N	0,98	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11241	11241	T	A	MI.17341	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	482	161	L	H	cTc/cAc	-3,17	0	0	probably_damaging	1	deleterious	0	neutral	3,46	deleterious	-8,45	deleterious	-5,41	high_impact	4,5	damaging	0,53	damaging	0,09	deleterious	4,19	23,8	0,03	0,35	NA	NA	disease	0,77	disease	0,73	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,18	0,8	47,28	9,47	N	0,4	N	0,96	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11243	11243	A	T	MI.17342	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	484	162	I	F	Atc/Ttc	-1,09	0	0	probably_damaging	0,97	neutral	0,33	neutral	4,76	neutral	0,88	deleterious	-3,09	low_impact	1,82	neutral	0,66	damaging	0,15	deleterious	3,72	23,3	0,16	0,45	NA	NA	disease	0,79	disease	0,57	disease	0,71	4	neutral	0,97	neutral	0,18	neutral	-2	deleterious	0,77	low_impact	-2,14	medium_impact	0,03	medium_impact	0,68	0,49	0,8	18,74	17,42	N	0,3	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11243	11243	A	C	MI.17343	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	484	162	I	L	Atc/Ctc	-1,09	0	0	possibly_damaging	0,61	neutral	0,57	neutral	4,8	neutral	1,13	neutral	-1,54	low_impact	0,98	neutral	0,7	damaging	0,28	deleterious	3,69	23,3	0,18	0,45	NA	NA	disease	0,62	neutral	0,31	neutral	0,48	0	neutral	0,56	deleterious	0,48	neutral	-3	deleterious	0,67	medium_impact	-0,9	medium_impact	0,27	medium_impact	-0,16	0,38	0,8	18,74	17,42	N	0,33	N	0,6	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11243	11243	A	G	MI.17344	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	484	162	I	V	Atc/Gtc	-1,09	0	0	benign	0,12	neutral	1	neutral	4,67	neutral	0,21	neutral	0,21	neutral_impact	-0,06	neutral	0,69	neutral	0,97	deleterious	0,27	5,44	0,35	0,5	NA	NA	neutral	0,06	neutral	0,26	neutral	0,17	7	neutral	0,11	deleterious	0,94	neutral	-6	deleterious	0,59	medium_impact	0,1	high_impact	1,88	low_impact	-1,19	0,26	0,8	18,74	17,42	N	0,36	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11244	11244	T	C	MI.17345	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	485	162	I	T	aTc/aCc	-0,4	0	0	probably_damaging	0,91	neutral	0,05	neutral	4,56	neutral	-1,37	deleterious	-2,87	medium_impact	2,56	neutral	0,77	neutral	0,41	deleterious	3,35	22,9	0,09	0,35	NA	NA	disease	0,6	neutral	0,38	neutral	0,49	0	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,72	low_impact	-1,66	medium_impact	-0,52	medium_impact	1,41	0,27	0,8	18,74	17,42	N	0,39	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11244	11244	T	A	MI.17346	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	485	162	I	N	aTc/aAc	-0,4	0	0	probably_damaging	0,98	deleterious	0,03	neutral	4,56	neutral	-1,4	deleterious	-4,91	medium_impact	2,9	neutral	0,68	damaging	0,2	deleterious	4,42	24,2	0,13	0,4	NA	NA	disease	0,85	disease	0,56	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,8	low_impact	-2,31	medium_impact	-0,64	medium_impact	1,74	0,27	0,8	18,74	17,42	N	0,33	N	0,98	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11244	11244	T	G	MI.17347	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	485	162	I	S	aTc/aGc	-0,4	0	0	probably_damaging	0,96	deleterious	0,02	neutral	4,54	neutral	-1,73	deleterious	-4,14	medium_impact	2,77	neutral	0,69	damaging	0,16	deleterious	4,24	23,9	0,06	0,35	NA	NA	disease	0,82	disease	0,54	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,78	low_impact	-2,01	medium_impact	-0,75	medium_impact	1,61	0,29	0,8	18,74	17,42	N	0,32	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11245	11245	C	A	MI.17348	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	486	162	I	M	atC/atA	7,44	0,95	0	probably_damaging	0,97	neutral	0,17	neutral	4,56	neutral	-1,23	neutral	-1,82	low_impact	1,19	neutral	0,69	neutral	0,36	deleterious	3,79	23,4	0,21	0,45	NA	NA	disease	0,54	neutral	0,33	neutral	0,47	1	deleterious	0,98	neutral	0,1	neutral	-2	deleterious	0,72	low_impact	-2,14	medium_impact	-0,18	medium_impact	0,05	0,45	0,8	18,74	17,42	P	0,54	P	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11245	11245	C	G	MI.17349	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	486	162	I	M	atC/atG	7,44	0,95	0	probably_damaging	0,97	neutral	0,17	neutral	4,56	neutral	-1,23	neutral	-1,82	low_impact	1,19	neutral	0,69	neutral	0,36	deleterious	3,3	22,9	0,21	0,45	NA	NA	disease	0,54	neutral	0,33	neutral	0,47	1	deleterious	0,98	neutral	0,1	neutral	-2	deleterious	0,72	low_impact	-2,14	medium_impact	-0,18	medium_impact	0,05	0,45	0,8	18,74	17,42	P	0,53	P	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8503	8503	T	G	MI.1735	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	138	46	N	K	aaT/aaG	-0,33	0	0,01	probably_damaging	0,92	neutral	1	neutral	1,62	neutral	1,87	neutral	1,47	neutral_impact	-1,44	neutral	0,98	neutral	0,94	neutral	1,31	12,3	0,91929012	0,95	neutral	0,1	neutral	0,06	neutral	0,28	neutral	0,03	9	neutral	0,92	deleterious	0,54	neutral	-2	deleterious	0,59	low_impact	-1,76	high_impact	1,98	low_impact	-2,33	0,81	0,85	NA	NA	N	0,37	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11246	11246	G	C	MI.17350	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	487	163	A	P	Gca/Cca	-11,7	0	0	possibly_damaging	0,73	deleterious	0,02	neutral	4,4	deleterious	-5,12	deleterious	-3,45	high_impact	3,7	neutral	0,63	neutral	0,33	deleterious	3,75	23,3	0,02	0,35	NA	NA	disease	0,9	disease	0,71	disease	0,8	6	deleterious	0,98	neutral	0,15	deleterious	5	deleterious	0,87	low_impact	-1,12	medium_impact	-0,75	high_impact	2,53	0,5	0,8	27,02	31,13	N	0,38	N	0,94	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11246	11246	G	A	MI.17351	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	487	163	A	T	Gca/Aca	-11,7	0	0	benign	0,03	neutral	0,25	neutral	4,45	deleterious	-3,22	neutral	-2,36	low_impact	1,88	neutral	0,73	neutral	0,85	deleterious	3,08	22,5	0,11	0,4	NA	NA	disease	0,63	disease	0,51	neutral	0,46	1	neutral	0,74	deleterious	0,61	neutral	-6	deleterious	0,75	medium_impact	0,7	medium_impact	-0,07	medium_impact	0,73	0,82	0,85	27,02	31,13	N	0,41	N	0,86	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11246	11246	G	T	MI.17352	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	487	163	A	S	Gca/Tca	-11,7	0	0	benign	0,27	neutral	0,44	neutral	4,51	neutral	-2,4	neutral	-1,94	low_impact	1,12	neutral	0,74	neutral	0,77	deleterious	3,6	23,2	0,23	0,45	NA	NA	disease	0,57	neutral	0,36	neutral	0,46	1	neutral	0,47	deleterious	0,59	neutral	-6	deleterious	0,77	medium_impact	-0,31	medium_impact	0,14	medium_impact	-0,02	0,39	0,8	27,02	31,13	N	0,36	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11247	11247	C	A	MI.17353	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	488	163	A	E	gCa/gAa	1,91	0,42	0	possibly_damaging	0,54	deleterious	0,03	neutral	4,43	deleterious	-4,42	deleterious	-3,43	medium_impact	3,36	neutral	0,64	neutral	0,41	deleterious	4,38	24,1	0,02	0,35	NA	NA	disease	0,91	disease	0,7	disease	0,8	6	neutral	0,97	neutral	0,25	deleterious	4	deleterious	0,85	medium_impact	-0,78	medium_impact	-0,64	high_impact	2,2	0,27	0,8	27,02	31,13	N	0,39	N	0,93	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11247	11247	C	G	MI.17354	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	488	163	A	G	gCa/gGa	1,91	0,42	0	benign	0,41	neutral	0,43	neutral	4,66	neutral	0,65	deleterious	-2,88	low_impact	1,31	neutral	0,65	neutral	0,54	deleterious	3,88	23,5	0,23	0,45	NA	NA	disease	0,61	disease	0,56	neutral	0,48	1	neutral	0,51	deleterious	0,51	neutral	-6	deleterious	0,75	medium_impact	-0,57	medium_impact	0,13	medium_impact	0,17	0,58	0,8	27,02	31,13	N	0,29	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11247	11247	C	T	MI.17355	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	488	163	A	V	gCa/gTa	1,91	0,42	0	benign	0,02	neutral	0,4	neutral	4,5	neutral	-2,44	neutral	-2,5	medium_impact	1,94	neutral	0,77	neutral	0,56	deleterious	4,35	24,1	0,08	0,35	NA	NA	disease	0,78	disease	0,54	disease	0,53	1	neutral	0,58	deleterious	0,69	neutral	-3	deleterious	0,8	medium_impact	0,87	medium_impact	0,1	medium_impact	0,79	0,8	0,85	27,02	31,13	N	0,27	N	0,61	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11249	11249	C	G	MI.17356	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	490	164	L	V	Cta/Gta	-5,93	0	0	probably_damaging	1	neutral	0,09	neutral	4,63	neutral	-0,71	neutral	-2,26	medium_impact	2,22	damaging	0,45	damaging	0,09	deleterious	3,36	22,9	0,28	0,45	NA	NA	disease	0,58	disease	0,59	disease	0,66	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,36	medium_impact	1,07	0,56	0,8	47,28	9,36	N	0,35	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11249	11249	C	A	MI.17357	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	490	164	L	M	Cta/Ata	-5,93	0	0	probably_damaging	1	neutral	0,11	neutral	4,59	neutral	-1,23	neutral	-1,5	medium_impact	2,34	damaging	0,48	damaging	0,11	deleterious	3,69	23,3	0,22	0,45	NA	NA	disease	0,53	neutral	0,49	disease	0,51	0	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	-0,31	medium_impact	1,19	0,53	0,8	47,28	9,36	N	0,38	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11250	11250	T	A	MI.17358	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	491	164	L	Q	cTa/cAa	-0,63	0	0	probably_damaging	1	deleterious	0	neutral	4,48	deleterious	-4,72	deleterious	-4,59	high_impact	3,97	damaging	0,41	damaging	0,06	deleterious	4,1	23,7	0,02	0,35	NA	NA	disease	0,79	disease	0,6	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	2,8	0,34	0,8	47,28	9,36	N	0,48	N	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11250	11250	T	G	MI.17359	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	491	164	L	R	cTa/cGa	-0,63	0	0	probably_damaging	1	deleterious	0	neutral	4,49	deleterious	-4,54	deleterious	-4,6	high_impact	3,97	damaging	0,38	damaging	0,05	deleterious	4,08	23,7	0,01	0,35	NA	NA	disease	0,87	disease	0,72	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	2,8	0,13	0,8	47,28	9,36	N	0,52	P	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8503	8503	T	A	MI.1736	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	138	46	N	K	aaT/aaA	-0,33	0	0,01	probably_damaging	0,92	neutral	1	neutral	1,62	neutral	1,87	neutral	1,47	neutral_impact	-1,44	neutral	0,98	neutral	0,94	neutral	1,58	13,73	0,91929012	0,95	neutral	0,1	neutral	0,06	neutral	0,28	neutral	0,03	9	neutral	0,92	deleterious	0,54	neutral	-2	deleterious	0,59	low_impact	-1,76	high_impact	1,98	low_impact	-2,33	0,81	0,85	NA	NA	N	0,37	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11250	11250	T	C	MI.17360	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	491	164	L	P	cTa/cCa	-0,63	0	0	probably_damaging	1	deleterious	0	neutral	4,48	deleterious	-5,11	deleterious	-5,37	high_impact	3,97	damaging	0,36	damaging	0,05	deleterious	3,87	23,5	0,02	0,35	NA	NA	disease	0,85	disease	0,73	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	2,8	0,39	0,8	47,28	9,36	N	0,52	P	0,98	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11252	11252	A	T	MI.17361	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	493	165	I	F	Att/Ttt	-5,93	0	0	benign	0,38	neutral	0,46	neutral	4,57	neutral	-0,76	neutral	-1,87	neutral_impact	0,64	neutral	0,72	neutral	0,57	deleterious	2,09	16,82	0,18	0,45	NA	NA	neutral	0,48	neutral	0,37	neutral	0,26	5	neutral	0,47	deleterious	0,54	neutral	-6	deleterious	0,46	medium_impact	-0,52	medium_impact	0,16	medium_impact	-0,49	0,57	0,8	8,5	11,75	N	0,32	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11252	11252	A	G	MI.17362	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	493	165	I	V	Att/Gtt	-5,93	0	0	benign	0,01	neutral	0,1	neutral	4,57	neutral	-0,36	neutral	-0,42	low_impact	1	neutral	0,82	neutral	0,98	deleterious	0,01	2,72	0,49	0,55	NA	NA	neutral	0,23	neutral	0,35	neutral	0,15	7	neutral	0,9	deleterious	0,55	neutral	-6	neutral	0,08	medium_impact	1,16	medium_impact	-0,33	medium_impact	-0,14	0,38	0,8	8,5	11,75	N	0,45	N	0,12	polymorphism	1	0,01	rs879229170	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11252	11252	A	C	MI.17363	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	493	165	I	L	Att/Ctt	-5,93	0	0	benign	0,01	neutral	1	neutral	4,76	neutral	0,5	neutral	0,24	neutral_impact	-1,19	neutral	0,74	neutral	0,97	neutral	-0,9	0,03	0,25	0,45	NA	NA	neutral	0,13	neutral	0,21	neutral	0,23	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,16	high_impact	1,88	low_impact	-2,3	0,51	0,8	8,5	11,75	N	0,31	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11253	11253	T	A	MI.17364	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	494	165	I	N	aTt/aAt	-0,86	0	0,01	benign	0,38	deleterious	0	neutral	4,46	deleterious	-4,28	deleterious	-3,41	medium_impact	2,29	neutral	0,68	neutral	0,53	deleterious	2,85	21,6	0,11	0,4	NA	NA	disease	0,73	disease	0,58	disease	0,73	5	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,46	medium_impact	-0,52	low_impact	-1,48	medium_impact	1,14	0,3	0,8	8,5	11,75	N	0,34	N	0,78	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11253	11253	T	G	MI.17365	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	494	165	I	S	aTt/aGt	-0,86	0	0,01	benign	0,02	deleterious	0,02	neutral	4,68	neutral	-1,18	deleterious	-2,62	low_impact	1,64	neutral	0,69	neutral	0,79	deleterious	2,34	18,43	0,04	0,35	NA	NA	disease	0,6	disease	0,55	disease	0,52	0	neutral	0,98	deleterious	0,5	neutral	-2	neutral	0,24	medium_impact	0,87	medium_impact	-0,75	medium_impact	0,5	0,28	0,8	8,5	11,75	N	0,4	N	0,26	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11253	11253	T	C	MI.17366	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	494	165	I	T	aTt/aCt	-0,86	0	0,01	benign	0,01	deleterious	0,02	neutral	4,5	neutral	-2,45	neutral	-1,46	low_impact	1,74	neutral	0,8	neutral	0,95	deleterious	0,33	6,02	0,08	0,35	NA	NA	neutral	0,36	neutral	0,39	neutral	0,15	7	neutral	0,98	deleterious	0,51	neutral	-2	neutral	0,1	medium_impact	1,16	medium_impact	-0,75	medium_impact	0,6	0,31	0,8	8,5	11,75	P	0,53	P	0,43	disease_causing_automatic	0	0,03	rs200145866	Pathogenic	Leber's_optic_atrophy	RCV000055696.1	MedGen:OMIM:SNOMED_CT	.	.	.	.	T11253C	LHON, PD	+	-	Reported	4
chrM	11254	11254	T	A	MI.17367	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	495	165	I	M	atT/atA	1,68	0,01	0	benign	0,03	neutral	0,19	neutral	4,52	neutral	-2,05	neutral	-0,63	neutral_impact	0,76	neutral	0,76	neutral	0,92	deleterious	2,13	17,02	0,33	0,5	NA	NA	neutral	0,34	neutral	0,32	neutral	0,14	7	neutral	0,8	deleterious	0,58	neutral	-6	deleterious	0,46	medium_impact	0,7	medium_impact	-0,15	medium_impact	-0,37	0,55	0,8	8,5	11,75	N	0,44	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11254	11254	T	G	MI.17368	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	495	165	I	M	atT/atG	1,68	0,01	0	benign	0,03	neutral	0,19	neutral	4,52	neutral	-2,05	neutral	-0,63	neutral_impact	0,76	neutral	0,76	neutral	0,92	deleterious	1,85	15,31	0,33	0,5	NA	NA	neutral	0,34	neutral	0,32	neutral	0,14	7	neutral	0,8	deleterious	0,58	neutral	-6	deleterious	0,46	medium_impact	0,7	medium_impact	-0,15	medium_impact	-0,37	0,55	0,8	8,5	11,75	N	0,45	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11255	11255	T	A	MI.17369	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	496	166	Y	N	Tac/Aac	-10,78	0	0,02	benign	0,23	neutral	0,26	neutral	4,52	deleterious	-3,98	deleterious	-3,63	medium_impact	2,17	neutral	0,76	neutral	0,72	neutral	0,93	10,26	0,09	0,35	NA	NA	disease	0,57	neutral	0,45	neutral	0,47	1	neutral	0,69	deleterious	0,52	neutral	-3	neutral	0,17	medium_impact	-0,23	medium_impact	-0,05	medium_impact	1,02	0,1	0,8	15,47	15,4	N	0,4	N	0,37	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8504	8504	T	C	MI.1737	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	139	47	Y	H	Tat/Cat	-3,57	0	0	possibly_damaging	0,49	neutral	0,57	neutral	1,28	deleterious	-4,61	neutral	1,55	neutral_impact	-1,95	neutral	1	neutral	0,96	neutral	-0,38	0,44	0,7567226	0,85	neutral	0,15	neutral	0,04	neutral	0,28	neutral	0,04	9	neutral	0,45	deleterious	0,54	neutral	-3	neutral	0,37	medium_impact	-0,74	medium_impact	0,36	low_impact	-2,77	0,59	0,85	NA	NA	N	0,38	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11255	11255	T	C	MI.17370	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	496	166	Y	H	Tac/Cac	-10,78	0	0,02	benign	0	neutral	0,37	neutral	4,51	deleterious	-3,76	neutral	-1,97	low_impact	1,8	neutral	0,76	neutral	0,98	deleterious	0,18	4,5	0,21	0,45	NA	NA	neutral	0,45	neutral	0,35	neutral	0,2	6	neutral	0,63	deleterious	0,69	neutral	-6	neutral	0,16	high_impact	2,1	medium_impact	0,07	medium_impact	0,66	0,14	0,8	15,47	15,4	N	0,42	N	0,01	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11255	11255	T	G	MI.17371	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	496	166	Y	D	Tac/Gac	-10,78	0	0,02	benign	0,29	neutral	0,12	neutral	4,51	deleterious	-4,93	deleterious	-4,39	medium_impact	2,64	neutral	0,75	neutral	0,52	deleterious	1,93	15,78	0,04	0,35	NA	NA	disease	0,71	disease	0,57	disease	0,71	4	neutral	0,86	neutral	0,42	neutral	-3	neutral	0,23	medium_impact	-0,35	medium_impact	-0,28	medium_impact	1,49	0,04	0,8	15,47	15,4	N	0,41	N	0,69	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11256	11256	A	G	MI.17372	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	497	166	Y	C	tAc/tGc	-2,24	0	0	possibly_damaging	0,79	neutral	0,1	neutral	4,51	deleterious	-3,46	deleterious	-3,64	medium_impact	2,3	neutral	0,75	neutral	0,48	deleterious	3,05	22,4	0,05	0,35	NA	NA	disease	0,71	neutral	0,48	neutral	0,5	0	neutral	0,93	neutral	0,16	NA	0	deleterious	0,58	low_impact	-1,26	medium_impact	-0,33	medium_impact	1,15	0,04	0,8	15,47	15,4	N	0,41	N	0,58	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11256	11256	A	C	MI.17373	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	497	166	Y	S	tAc/tCc	-2,24	0	0	benign	0,23	neutral	0,42	neutral	4,56	neutral	-2,25	deleterious	-3,3	low_impact	1,27	neutral	0,73	neutral	0,98	deleterious	0,35	6,2	0,07	0,35	NA	NA	neutral	0,46	neutral	0,34	neutral	0,23	5	neutral	0,49	deleterious	0,6	neutral	-6	neutral	0,16	medium_impact	-0,23	medium_impact	0,12	medium_impact	0,13	0,12	0,8	15,47	15,4	N	0,39	N	0,22	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11256	11256	A	T	MI.17374	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	497	166	Y	F	tAc/tTc	-2,24	0	0	benign	0	neutral	0,59	neutral	4,54	neutral	-0,67	neutral	-1,19	low_impact	0,9	neutral	0,78	neutral	0,97	deleterious	-0,06	2,04	0,33	0,5	NA	NA	neutral	0,33	neutral	0,23	neutral	0,18	6	neutral	0,4	deleterious	0,8	neutral	-6	neutral	0,17	high_impact	2,1	medium_impact	0,29	medium_impact	-0,24	0,28	0,8	15,47	15,4	N	0,35	N	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11258	11258	A	C	MI.17375	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	499	167	T	P	Act/Cct	-10,08	0	0	possibly_damaging	0,73	deleterious	0	neutral	4,58	deleterious	-3,51	neutral	-1,73	low_impact	1,66	neutral	0,67	neutral	0,48	deleterious	3,37	22,9	0,05	0,35	NA	NA	disease	0,77	disease	0,59	disease	0,77	5	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-1,12	low_impact	-1,48	medium_impact	0,52	0,42	0,8	23,97	18,24	N	0,35	N	0,86	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11258	11258	A	T	MI.17376	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	499	167	T	S	Act/Tct	-10,08	0	0	benign	0,27	deleterious	0,03	neutral	4,63	neutral	-1,27	neutral	-0,86	neutral_impact	0,46	neutral	0,8	neutral	0,84	deleterious	3,08	22,5	0,4	0,5	NA	NA	neutral	0,29	neutral	0,42	neutral	0,17	7	neutral	0,97	neutral	0,38	neutral	-2	deleterious	0,71	medium_impact	-0,31	medium_impact	-0,64	medium_impact	-0,67	0,64	0,8	23,97	18,24	N	0,43	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11258	11258	A	G	MI.17377	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	499	167	T	A	Act/Gct	-10,08	0	0	benign	0,02	deleterious	0,03	neutral	4,64	neutral	-0,12	neutral	-0,33	neutral_impact	0,62	neutral	0,78	neutral	0,89	deleterious	3,26	22,8	0,28	0,45	NA	NA	neutral	0,24	neutral	0,45	neutral	0,17	7	neutral	0,97	deleterious	0,51	neutral	-2	deleterious	0,7	medium_impact	0,87	medium_impact	-0,64	medium_impact	-0,51	0,36	0,8	23,97	18,24	N	0,44	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11259	11259	C	T	MI.17378	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	500	167	T	I	aCt/aTt	-1,32	0	0	benign	0,02	neutral	0,37	neutral	4,86	neutral	1,02	neutral	1,96	neutral_impact	-1,01	neutral	0,77	neutral	0,99	deleterious	2,42	18,93	0,11	0,4	NA	NA	neutral	0,24	neutral	0,2	neutral	0,18	6	neutral	0,62	deleterious	0,68	neutral	-6	deleterious	0,7	medium_impact	0,87	medium_impact	0,07	low_impact	-2,13	0,56	0,8	23,97	18,24	N	0,36	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11259	11259	C	G	MI.17379	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	500	167	T	S	aCt/aGt	-1,32	0	0	benign	0,27	deleterious	0,03	neutral	4,63	neutral	-1,27	neutral	-0,86	neutral_impact	0,46	neutral	0,8	neutral	0,84	deleterious	3,43	23	0,4	0,5	NA	NA	neutral	0,29	neutral	0,42	neutral	0,17	7	neutral	0,97	neutral	0,38	neutral	-2	deleterious	0,71	medium_impact	-0,31	medium_impact	-0,64	medium_impact	-0,67	0,64	0,8	23,97	18,24	N	0,43	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8504	8504	T	A	MI.1738	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	139	47	Y	N	Tat/Aat	-3,57	0	0	benign	0,37	neutral	0,52	neutral	1,27	deleterious	-6,24	neutral	-1,74	neutral_impact	-0,08	neutral	1	neutral	0,74	neutral	1,3	12,25	0,71795062	0,85	neutral	0,25	neutral	0,28	neutral	0,33	neutral	0,13	7	neutral	0,41	deleterious	0,58	neutral	-6	neutral	0,42	medium_impact	-0,54	medium_impact	0,31	low_impact	-1,17	0,47	0,85	NA	NA	N	0,41	N	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11259	11259	C	A	MI.17380	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	500	167	T	N	aCt/aAt	-1,32	0	0	possibly_damaging	0,51	deleterious	0,03	neutral	4,61	neutral	-2,77	neutral	-1,59	neutral_impact	0,77	neutral	0,69	neutral	0,66	deleterious	3,52	23,1	0,27	0,45	NA	NA	disease	0,52	neutral	0,44	disease	0,52	0	neutral	0,97	neutral	0,26	deleterious	1	deleterious	0,74	medium_impact	-0,73	medium_impact	-0,64	medium_impact	-0,36	0,64	0,8	23,97	18,24	N	0,4	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11261	11261	C	A	MI.17381	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	502	168	H	N	Cac/Aac	-14,93	0	0	benign	0,01	neutral	0,31	neutral	4,63	neutral	-0,72	neutral	-0,72	neutral_impact	-0,18	neutral	0,75	neutral	0,84	deleterious	2	16,22	0,23	0,45	NA	NA	neutral	0,47	neutral	0,38	neutral	0,26	5	neutral	0,69	deleterious	0,65	neutral	-6	neutral	0,22	medium_impact	1,16	medium_impact	0,01	low_impact	-1,3	0,24	0,8	30,72	29,62	N	0,43	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11261	11261	C	G	MI.17382	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	502	168	H	D	Cac/Gac	-14,93	0	0	benign	0,11	neutral	0,13	neutral	4,62	neutral	-1,59	neutral	-1,08	low_impact	1,21	neutral	0,75	neutral	0,56	deleterious	1,98	16,08	0,05	0,35	NA	NA	disease	0,68	disease	0,65	disease	0,7	4	neutral	0,85	deleterious	0,51	neutral	-6	neutral	0,32	medium_impact	0,14	medium_impact	-0,26	medium_impact	0,07	0,24	0,8	30,72	29,62	N	0,37	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11261	11261	C	T	MI.17383	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	502	168	H	Y	Cac/Tac	-14,93	0	0	benign	0	neutral	1	neutral	5	neutral	3,79	neutral	-0,59	neutral_impact	-0,71	neutral	0,79	neutral	0,85	deleterious	0,57	7,92	0,27	0,45	NA	NA	neutral	0,31	neutral	0,31	neutral	0,15	7	neutral	0	deleterious	1	neutral	-6	neutral	0,16	high_impact	2,1	high_impact	1,88	low_impact	-1,83	0,19	0,8	30,72	29,62	N	0,24	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11262	11262	A	G	MI.17384	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	503	168	H	R	cAc/cGc	-0,4	0	0	benign	0,11	neutral	0,19	neutral	4,64	neutral	-0,46	neutral	-0,21	low_impact	1,9	neutral	0,8	neutral	0,58	neutral	1,07	11,06	0,12	0,4	NA	NA	disease	0,72	disease	0,57	disease	0,72	4	neutral	0,78	deleterious	0,54	neutral	-6	neutral	0,29	medium_impact	0,14	medium_impact	-0,15	medium_impact	0,75	0,25	0,8	30,72	29,62	N	0,33	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11262	11262	A	T	MI.17385	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	503	168	H	L	cAc/cTc	-0,4	0	0	benign	0	neutral	0,49	neutral	4,88	neutral	3,21	neutral	-2,03	neutral_impact	0,26	neutral	0,75	neutral	0,84	deleterious	1,82	15,09	0,06	0,35	NA	NA	disease	0,75	disease	0,52	disease	0,63	3	neutral	0,51	deleterious	0,75	neutral	-6	neutral	0,24	high_impact	2,1	medium_impact	0,19	medium_impact	-0,87	0,1	0,8	30,72	29,62	N	0,35	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11262	11262	A	C	MI.17386	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	503	168	H	P	cAc/cCc	-0,4	0	0	benign	0,36	neutral	0,11	neutral	4,63	neutral	-1,06	neutral	-1,71	medium_impact	2,25	neutral	0,69	neutral	0,41	neutral	1,55	13,57	0,05	0,35	NA	NA	disease	0,88	disease	0,69	disease	0,82	6	neutral	0,87	neutral	0,38	neutral	-3	deleterious	0,48	medium_impact	-0,48	medium_impact	-0,31	medium_impact	1,1	0,08	0,8	30,72	29,62	N	0,35	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11263	11263	C	A	MI.17387	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	504	168	H	Q	caC/caA	6,75	0,85	0	benign	0,01	neutral	0,5	neutral	4,63	neutral	-0,62	neutral	1,96	neutral_impact	-0,52	neutral	0,73	neutral	0,97	neutral	-0,79	0,05	0,18	0,45	NA	NA	neutral	0,11	neutral	0,29	neutral	0,19	6	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	1,16	medium_impact	0,2	low_impact	-1,64	0,34	0,8	30,72	29,62	N	0,5	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11263	11263	C	G	MI.17388	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	504	168	H	Q	caC/caG	6,75	0,85	0	benign	0,01	neutral	0,5	neutral	4,63	neutral	-0,62	neutral	1,96	neutral_impact	-0,52	neutral	0,73	neutral	0,97	neutral	-1,17	0,01	0,18	0,45	NA	NA	neutral	0,11	neutral	0,29	neutral	0,19	6	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	1,16	medium_impact	0,2	low_impact	-1,64	0,34	0,8	30,72	29,62	N	0,5	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11264	11264	A	G	MI.17389	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	505	169	N	D	Aac/Gac	-1,78	0	0	possibly_damaging	0,89	neutral	0,12	neutral	4,59	neutral	-1,76	deleterious	-2,74	medium_impact	2,25	neutral	0,76	neutral	0,31	deleterious	3,65	23,2	0,49	0,55	NA	NA	disease	0,73	disease	0,67	disease	0,68	4	neutral	0,96	neutral	0,12	NA	0	deleterious	0,8	low_impact	-1,57	medium_impact	-0,28	medium_impact	1,1	0,28	0,8	20,26	14,59	N	0,37	N	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8504	8504	T	G	MI.1739	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	139	47	Y	D	Tat/Gat	-3,57	0	0	benign	0,37	neutral	0,44	neutral	1,27	deleterious	-7,16	deleterious	-2,81	neutral_impact	0,34	neutral	0,99	neutral	0,4	neutral	1,16	11,51	0,68116519	0,85	neutral	0,27	neutral	0,31	neutral	0,44	neutral	0,15	7	neutral	0,49	deleterious	0,54	neutral	-6	neutral	0,42	medium_impact	-0,54	medium_impact	0,23	medium_impact	-0,81	0,53	0,85	NA	NA	N	0,42	N	0,35	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11264	11264	A	T	MI.17390	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	505	169	N	Y	Aac/Tac	-1,78	0	0	probably_damaging	0,99	neutral	0,24	neutral	4,68	neutral	0,63	deleterious	-4,69	low_impact	1,64	neutral	0,77	damaging	0,21	deleterious	3,49	23,1	0,11	0,4	NA	NA	disease	0,81	neutral	0,41	disease	0,54	1	deleterious	0,99	neutral	0,13	neutral	-2	deleterious	0,82	low_impact	-2,59	medium_impact	-0,08	medium_impact	0,5	0,3	0,8	20,26	14,59	N	0,27	N	0,62	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11264	11264	A	C	MI.17391	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	505	169	N	H	Aac/Cac	-1,78	0	0	probably_damaging	0,99	neutral	0,11	neutral	4,62	neutral	-0,59	deleterious	-2,83	low_impact	1,79	neutral	0,77	neutral	0,44	deleterious	2,88	21,8	0,33	0,5	NA	NA	disease	0,75	neutral	0,46	disease	0,54	1	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,8	low_impact	-2,59	medium_impact	-0,31	medium_impact	0,65	0,2	0,8	20,26	14,59	N	0,32	N	0,69	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11265	11265	A	C	MI.17392	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	506	169	N	T	aAc/aCc	0,52	0	0	probably_damaging	0,95	neutral	0,22	neutral	4,65	neutral	0,07	deleterious	-3,26	low_impact	1,61	neutral	0,72	neutral	0,81	deleterious	2,12	16,96	0,25	0,45	NA	NA	neutral	0,48	neutral	0,3	neutral	0,3	4	neutral	0,97	neutral	0,14	neutral	-2	deleterious	0,73	low_impact	-1,92	medium_impact	-0,11	medium_impact	0,47	0,31	0,8	20,26	14,59	N	0,41	N	0,79	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11265	11265	A	T	MI.17393	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	506	169	N	I	aAc/aTc	0,52	0	0	probably_damaging	0,98	neutral	0,08	neutral	4,65	neutral	0,09	deleterious	-5,42	medium_impact	2,13	neutral	0,79	damaging	0,22	deleterious	3,92	23,5	0,13	0,4	NA	NA	disease	0,85	disease	0,57	disease	0,71	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,82	low_impact	-2,31	medium_impact	-0,39	medium_impact	0,98	0,21	0,8	20,26	14,59	N	0,28	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11265	11265	A	G	MI.17394	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	506	169	N	S	aAc/aGc	0,52	0	0	possibly_damaging	0,86	neutral	0,43	neutral	4,7	neutral	0,83	deleterious	-2,58	neutral_impact	0,72	neutral	0,71	neutral	0,9	deleterious	1,92	15,73	0,46	0,55	NA	NA	disease	0,51	neutral	0,33	neutral	0,45	1	neutral	0,85	neutral	0,29	neutral	-3	deleterious	0,76	low_impact	-1,46	medium_impact	0,13	medium_impact	-0,41	0,2	0,8	20,26	14,59	N	0,34	N	0,85	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11266	11266	C	G	MI.17395	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	507	169	N	K	aaC/aaG	0,06	0	0	probably_damaging	0,94	neutral	0,34	neutral	4,61	neutral	-0,78	deleterious	-2,88	low_impact	1,38	neutral	0,75	neutral	0,77	deleterious	2,46	19,21	0,4	0,5	NA	NA	disease	0,72	neutral	0,44	disease	0,52	0	neutral	0,94	neutral	0,2	neutral	-2	deleterious	0,81	low_impact	-1,84	medium_impact	0,04	medium_impact	0,24	0,37	0,8	20,26	14,59	N	0,36	N	0,95	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11266	11266	C	A	MI.17396	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	507	169	N	K	aaC/aaA	0,06	0	0	probably_damaging	0,94	neutral	0,34	neutral	4,61	neutral	-0,78	deleterious	-2,88	low_impact	1,38	neutral	0,75	neutral	0,77	deleterious	2,9	21,9	0,4	0,5	NA	NA	disease	0,72	neutral	0,44	disease	0,52	0	neutral	0,94	neutral	0,2	neutral	-2	deleterious	0,81	low_impact	-1,84	medium_impact	0,04	medium_impact	0,24	0,37	0,8	20,26	14,59	N	0,35	N	0,95	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11267	11267	A	T	MI.17397	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	508	170	T	S	Acc/Tcc	-6,63	0	0	benign	0,01	neutral	0,69	neutral	4,68	neutral	0,52	neutral	0,53	neutral_impact	0,24	neutral	0,75	neutral	1	deleterious	0,38	6,43	0,38	0,5	NA	NA	neutral	0,13	neutral	0,16	neutral	0,2	6	neutral	0,29	deleterious	0,84	neutral	-6	deleterious	0,68	medium_impact	1,16	medium_impact	0,4	medium_impact	-0,89	0,5	0,8	21,57	16,77	N	0,43	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11267	11267	A	C	MI.17398	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	508	170	T	P	Acc/Ccc	-6,63	0	0	benign	0,4	neutral	0,2	neutral	4,57	neutral	-2,44	neutral	-1,64	medium_impact	2,68	neutral	0,66	neutral	0,42	deleterious	3,28	22,8	0,04	0,35	NA	NA	disease	0,8	disease	0,51	disease	0,69	4	neutral	0,77	neutral	0,4	neutral	-3	deleterious	0,8	medium_impact	-0,55	medium_impact	-0,14	medium_impact	1,53	0,29	0,8	21,57	16,77	N	0,34	N	0,72	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11267	11267	A	G	MI.17399	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	508	170	T	A	Acc/Gcc	-6,63	0	0	benign	0,12	neutral	0,51	neutral	4,66	neutral	0,21	neutral	-0,91	low_impact	1,4	neutral	0,79	neutral	0,8	deleterious	2,16	17,22	0,29	0,45	NA	NA	neutral	0,3	neutral	0,35	neutral	0,16	7	neutral	0,41	deleterious	0,7	neutral	-6	deleterious	0,7	medium_impact	0,1	medium_impact	0,21	medium_impact	0,26	0,29	0,8	21,57	16,77	N	0,33	N	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8606	8606	C	G	MI.174	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	80	27	P	R	cCc/cGc	5,45	1	0	probably_damaging	1	neutral	0,35	neutral	4,34	neutral	-1,48	deleterious	-8,12	high_impact	3,86	neutral	0,66	neutral	0,43	deleterious	3,45	23	0,28	0,65	neutral	0,42	disease	0,88	disease	0,73	disease	0,8	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,14	high_impact	2,21	0,51	0,9	48,23	8,81	P	0,55	P	0,7	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8505	8505	A	G	MI.1740	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	140	47	Y	C	tAt/tGt	-0,57	0	0	possibly_damaging	0,66	neutral	0,18	neutral	1,27	deleterious	-5,97	deleterious	-3,94	low_impact	0,9	neutral	1	neutral	0,37	deleterious	2,06	16,61	0,74880421	0,85	disease	0,56	neutral	0,22	disease	0,52	neutral	0,16	7	neutral	0,84	neutral	0,26	neutral	-3	deleterious	0,55	low_impact	-1,03	medium_impact	-0,08	medium_impact	-0,33	0,15	0,85	NA	NA	N	0,55	P	0,58	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11268	11268	C	G	MI.17400	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	509	170	T	S	aCc/aGc	-3,86	0	0	benign	0,01	neutral	0,69	neutral	4,68	neutral	0,52	neutral	0,53	neutral_impact	0,24	neutral	0,75	neutral	1	deleterious	0,77	9,28	0,38	0,5	NA	NA	neutral	0,13	neutral	0,16	neutral	0,2	6	neutral	0,29	deleterious	0,84	neutral	-6	deleterious	0,68	medium_impact	1,16	medium_impact	0,4	medium_impact	-0,89	0,5	0,8	21,57	16,77	N	0,43	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11268	11268	C	T	MI.17401	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	509	170	T	I	aCc/aTc	-3,86	0	0	benign	0,26	neutral	0,43	neutral	4,74	neutral	1,1	neutral	-1,86	neutral_impact	0,68	neutral	0,79	neutral	0,87	deleterious	2,83	21,5	0,14	0,4	NA	NA	disease	0,53	neutral	0,38	disease	0,51	0	neutral	0,48	deleterious	0,59	neutral	-6	deleterious	0,74	medium_impact	-0,29	medium_impact	0,13	medium_impact	-0,45	0,44	0,8	21,57	16,77	N	0,28	N	0,45	polymorphism	1	0,02	rs879011423	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11268	11268	C	A	MI.17402	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	509	170	T	N	aCc/aAc	-3,86	0	0	benign	0	neutral	0,51	neutral	4,63	neutral	-0,18	neutral	0,35	neutral_impact	-0,15	neutral	0,77	neutral	0,99	neutral	1,54	13,51	0,31	0,45	NA	NA	neutral	0,3	neutral	0,19	neutral	0,16	7	neutral	0,48	deleterious	0,76	neutral	-6	deleterious	0,7	high_impact	2,1	medium_impact	0,21	low_impact	-1,27	0,63	0,8	21,57	16,77	N	0,41	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11270	11270	C	G	MI.17403	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	511	171	L	V	Cta/Gta	-11,01	0	0	benign	0,06	neutral	0,51	neutral	4,63	neutral	-0,53	neutral	-0,62	low_impact	1,07	neutral	0,81	neutral	0,97	deleterious	2,16	17,28	0,4	0,5	NA	NA	neutral	0,23	neutral	0,37	neutral	0,16	7	neutral	0,43	deleterious	0,73	neutral	-6	deleterious	0,69	medium_impact	0,41	medium_impact	0,21	medium_impact	-0,07	0,44	0,8	5,45	10,35	N	0,36	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11270	11270	C	A	MI.17404	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	511	171	L	M	Cta/Ata	-11,01	0	0	benign	0,32	neutral	0,27	neutral	4,6	neutral	-2,07	neutral	-0,09	neutral_impact	0,36	neutral	0,79	neutral	0,96	deleterious	2,17	17,32	0,32	0,5	NA	NA	neutral	0,12	neutral	0,21	neutral	0,26	5	neutral	0,68	deleterious	0,48	neutral	-6	deleterious	0,67	medium_impact	-0,41	medium_impact	-0,04	medium_impact	-0,77	0,44	0,8	5,45	10,35	N	0,45	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11271	11271	T	C	MI.17405	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	512	171	L	P	cTa/cCa	-3,86	0	0	probably_damaging	0,9	neutral	0,21	neutral	4,56	deleterious	-4,13	deleterious	-2,55	medium_impact	2,7	neutral	0,63	neutral	0,44	deleterious	3,82	23,4	0,02	0,35	NA	NA	disease	0,76	neutral	0,45	disease	0,59	2	neutral	0,94	neutral	0,16	deleterious	1	deleterious	0,82	low_impact	-1,61	medium_impact	-0,12	medium_impact	1,55	0,05	0,8	5,45	10,35	N	0,38	N	0,88	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11271	11271	T	G	MI.17406	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	512	171	L	R	cTa/cGa	-3,86	0	0	possibly_damaging	0,87	neutral	0,35	neutral	4,59	deleterious	-3,51	neutral	-2,06	medium_impact	2,15	neutral	0,72	neutral	0,51	deleterious	4,05	23,7	0,03	0,35	NA	NA	disease	0,7	disease	0,59	disease	0,72	4	neutral	0,88	neutral	0,24	NA	0	deleterious	0,81	low_impact	-1,49	medium_impact	0,05	medium_impact	1	0,09	0,8	5,45	10,35	N	0,32	N	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11271	11271	T	A	MI.17407	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	512	171	L	Q	cTa/cAa	-3,86	0	0	probably_damaging	0,9	neutral	0,32	neutral	4,59	deleterious	-3,25	neutral	-1,84	low_impact	1,66	neutral	0,77	neutral	0,69	deleterious	3,93	23,5	0,05	0,35	NA	NA	neutral	0,49	neutral	0,44	neutral	0,47	1	neutral	0,92	neutral	0,21	neutral	-2	deleterious	0,73	low_impact	-1,61	medium_impact	0,02	medium_impact	0,52	0,09	0,8	5,45	10,35	N	0,36	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11273	11273	G	A	MI.17408	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	514	172	G	S	Ggc/Agc	-2,01	0	0	probably_damaging	1	neutral	0,16	neutral	4,49	deleterious	-4,21	deleterious	-4,24	medium_impact	2,06	neutral	0,73	damaging	0,21	deleterious	4,11	23,7	0,07	0,35	NA	NA	disease	0,7	neutral	0,34	disease	0,51	0	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	-0,2	medium_impact	0,91	0,52	0,8	47,71	9,06	N	0,38	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11273	11273	G	C	MI.17409	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	514	172	G	R	Ggc/Cgc	-2,01	0	0	probably_damaging	1	deleterious	0,01	neutral	4,31	deleterious	-4,48	deleterious	-5,68	high_impact	3,54	neutral	0,64	damaging	0,09	deleterious	3,82	23,4	0,03	0,35	NA	NA	disease	0,9	disease	0,76	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,91	low_impact	-3,54	medium_impact	-0,92	high_impact	2,38	0,49	0,8	47,71	9,06	N	0,33	N	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8505	8505	A	C	MI.1741	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	140	47	Y	S	tAt/tCt	-0,57	0	0	benign	0,19	neutral	0,77	neutral	1,27	deleterious	-5,65	neutral	-2,2	neutral_impact	-0,52	neutral	0,99	neutral	0,73	deleterious	0,44	6,98	0,67050158	0,85	neutral	0,2	neutral	0,18	neutral	0,32	neutral	0,12	8	neutral	0,13	deleterious	0,79	neutral	-6	neutral	0,19	medium_impact	-0,16	medium_impact	0,59	low_impact	-1,54	0,4	0,85	NA	NA	N	0,37	N	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11273	11273	G	T	MI.17410	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	514	172	G	C	Ggc/Tgc	-2,01	0	0	probably_damaging	1	deleterious	0,02	neutral	4,26	deleterious	-8,01	deleterious	-6,42	medium_impact	2,92	neutral	0,74	damaging	0,09	deleterious	4,07	23,7	0,03	0,35	NA	NA	disease	0,88	disease	0,61	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,87	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,76	0,17	0,8	47,71	9,06	N	0,27	N	0,98	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11274	11274	G	C	MI.17411	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	515	172	G	A	gGc/gCc	4,44	1	0	probably_damaging	1	deleterious	0,04	neutral	4,33	deleterious	-3,86	deleterious	-4,26	medium_impact	2,54	neutral	0,74	damaging	0,2	deleterious	3,05	22,4	0,08	0,35	NA	NA	disease	0,63	disease	0,58	disease	0,59	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,83	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,39	0,36	0,8	47,71	9,06	P	0,54	P	0,76	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11274	11274	G	T	MI.17412	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	515	172	G	V	gGc/gTc	4,44	1	0	probably_damaging	1	deleterious	0,01	neutral	4,29	deleterious	-5,33	deleterious	-6,37	medium_impact	2,99	neutral	0,67	damaging	0,11	deleterious	3,69	23,3	0,03	0,35	NA	NA	disease	0,83	disease	0,62	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,88	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,83	0,15	0,8	47,71	9,06	N	0,43	N	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11274	11274	G	A	MI.17413	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	515	172	G	D	gGc/gAc	4,44	1	0	probably_damaging	1	neutral	0,08	neutral	4,31	deleterious	-4,18	deleterious	-5,01	medium_impact	1,95	neutral	0,7	damaging	0,13	deleterious	3,8	23,4	0,03	0,35	NA	NA	disease	0,88	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,89	low_impact	-3,54	medium_impact	-0,39	medium_impact	0,8	0,18	0,8	47,71	9,06	N	0,47	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11276	11276	T	C	MI.17414	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	517	173	S	P	Tca/Cca	-5,93	0	0	probably_damaging	1	deleterious	0,01	neutral	4,34	deleterious	-3,83	deleterious	-3,06	medium_impact	2,72	damaging	0,58	damaging	0,11	deleterious	3,94	23,5	0,04	0,35	NA	NA	disease	0,88	disease	0,67	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,57	0,12	0,8	37,04	8,79	N	0,25	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11276	11276	T	G	MI.17415	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	517	173	S	A	Tca/Gca	-5,93	0	0	probably_damaging	1	deleterious	0,03	neutral	4,41	neutral	-1,88	neutral	-1,78	medium_impact	2,21	neutral	0,67	damaging	0,22	deleterious	3,66	23,2	0,27	0,45	NA	NA	neutral	0,46	disease	0,67	neutral	0,46	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,74	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,06	0,26	0,8	37,04	8,79	N	0,33	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11276	11276	T	A	MI.17416	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	517	173	S	T	Tca/Aca	-5,93	0	0	probably_damaging	1	neutral	1	neutral	4,49	neutral	0,28	neutral	-0,45	neutral_impact	0,34	neutral	0,69	neutral	0,98	neutral	1,1	11,23	0,32	0,5	NA	NA	neutral	0,08	neutral	0,27	neutral	0,22	6	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,68	low_impact	-3,54	high_impact	1,88	medium_impact	-0,79	0,48	0,8	37,04	8,79	N	0,37	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11277	11277	C	G	MI.17417	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	518	173	S	W	tCa/tGa	-1,32	0	0	probably_damaging	1	deleterious	0,01	neutral	4,32	deleterious	-7,03	deleterious	-4,34	medium_impact	2,98	neutral	0,64	damaging	0,12	deleterious	4,28	24	0,07	0,35	NA	NA	disease	0,88	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,82	0,08	0,8	37,04	8,79	N	0,27	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11277	11277	C	T	MI.17418	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	518	173	S	L	tCa/tTa	-1,32	0	0	probably_damaging	1	neutral	0,07	neutral	4,39	deleterious	-3,53	deleterious	-3,57	medium_impact	2,48	neutral	0,72	damaging	0,19	deleterious	4,59	24,4	0,05	0,35	NA	NA	disease	0,82	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,43	medium_impact	1,33	0,31	0,8	37,04	8,79	N	0,33	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11279	11279	C	G	MI.17419	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	520	174	L	V	Cta/Gta	-9,16	0	0	possibly_damaging	0,89	neutral	0,08	neutral	4,5	neutral	-0,87	neutral	-2,14	medium_impact	2,56	neutral	0,73	neutral	0,54	deleterious	3,37	22,9	0,35	0,5	NA	NA	neutral	0,44	neutral	0,5	neutral	0,22	6	neutral	0,97	neutral	0,1	NA	0	deleterious	0,78	low_impact	-1,57	medium_impact	-0,39	medium_impact	1,41	0,61	0,8	43,36	8,24	N	0,43	N	0,5	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8505	8505	A	T	MI.1742	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	140	47	Y	F	tAt/tTt	-0,57	0	0	benign	0	neutral	0,68	neutral	2,7	neutral	2,79	neutral	-1,96	neutral_impact	0	neutral	1	neutral	0,87	neutral	-0,72	0,06	0,45432647	0,85	neutral	0,35	neutral	0,05	neutral	0,28	neutral	0,04	9	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,11	high_impact	2,09	medium_impact	0,48	low_impact	-1,1	0,34	0,85	NA	NA	N	0,45	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11279	11279	C	A	MI.17420	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	520	174	L	M	Cta/Ata	-9,16	0	0	probably_damaging	0,99	neutral	0,16	neutral	4,35	deleterious	-3,08	neutral	-1,36	medium_impact	2,17	neutral	0,8	neutral	0,59	deleterious	3,7	23,3	0,32	0,5	NA	NA	neutral	0,4	neutral	0,3	neutral	0,19	6	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,76	low_impact	-2,59	medium_impact	-0,2	medium_impact	1,02	0,53	0,8	43,36	8,24	N	0,4	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11280	11280	T	A	MI.17421	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	521	174	L	Q	cTa/cAa	-0,63	0	0	probably_damaging	0,98	deleterious	0,01	neutral	4,33	deleterious	-4,22	deleterious	-4,4	high_impact	3,58	neutral	0,7	neutral	0,37	deleterious	4,12	23,8	0,03	0,35	NA	NA	disease	0,77	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-2,31	medium_impact	-0,92	high_impact	2,42	0,19	0,8	43,36	8,24	N	0,36	N	0,88	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11280	11280	T	C	MI.17422	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	521	174	L	P	cTa/cCa	-0,63	0	0	probably_damaging	0,98	deleterious	0,03	neutral	4,32	deleterious	-4,62	deleterious	-5,17	medium_impact	2,95	neutral	0,63	neutral	0,53	deleterious	3,89	23,5	0,02	0,35	NA	NA	disease	0,76	disease	0,56	disease	0,53	1	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,89	low_impact	-2,31	medium_impact	-0,64	medium_impact	1,79	0,11	0,8	43,36	8,24	N	0,35	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	COSM1472304	.	.	.	.	.	.	.	.
chrM	11280	11280	T	G	MI.17423	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	521	174	L	R	cTa/cGa	-0,63	0	0	probably_damaging	0,98	deleterious	0,03	neutral	4,33	deleterious	-4,04	deleterious	-4,44	medium_impact	3,37	neutral	0,62	neutral	0,32	deleterious	4,11	23,7	0,02	0,35	NA	NA	disease	0,83	disease	0,75	disease	0,79	6	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,89	low_impact	-2,31	medium_impact	-0,64	high_impact	2,21	0,07	0,8	43,36	8,24	N	0,36	N	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11282	11282	A	G	MI.17424	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	523	175	N	D	Aac/Gac	-1,32	0	0	possibly_damaging	0,74	neutral	0,29	neutral	4,61	neutral	-0,36	deleterious	-2,66	low_impact	1,57	neutral	0,73	neutral	0,39	deleterious	3,76	23,3	0,47	0,55	neutral	0,4	neutral	0,48	disease	0,56	neutral	0,49	0	neutral	0,81	neutral	0,28	neutral	-3	deleterious	0,7	low_impact	-1,14	medium_impact	-0,02	medium_impact	0,43	0,21	0,8	17,43	20,8	N	0,38	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11282	11282	A	C	MI.17425	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	523	175	N	H	Aac/Cac	-1,32	0	0	probably_damaging	0,98	neutral	0,54	neutral	4,53	deleterious	-3,21	neutral	-2,08	medium_impact	2,66	neutral	0,72	neutral	0,77	deleterious	1,81	15,04	0,26	0,45	disease	0,64	neutral	0,34	neutral	0,39	disease	0,62	2	deleterious	0,98	neutral	0,28	deleterious	1	deleterious	0,73	low_impact	-2,31	medium_impact	0,24	medium_impact	1,51	0,18	0,8	17,43	20,8	N	0,34	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11282	11282	A	T	MI.17426	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	523	175	N	Y	Aac/Tac	-1,32	0	0	probably_damaging	0,98	neutral	1	neutral	4,52	deleterious	-4,04	deleterious	-4,13	medium_impact	2,32	neutral	0,8	neutral	0,61	deleterious	3,67	23,3	0,07	0,35	disease	0,77	disease	0,56	neutral	0,36	disease	0,54	1	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,78	low_impact	-2,31	high_impact	1,88	medium_impact	1,17	0,13	0,8	17,43	20,8	N	0,2	N	0,91	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11283	11283	A	G	MI.17427	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	524	175	N	S	aAc/aGc	1,91	0,91	0	benign	0,2	neutral	0,92	neutral	4,68	neutral	-0,68	neutral	-1,79	neutral_impact	0,52	neutral	0,6	neutral	0,71	deleterious	0,23	4,98	0,51	0,6	neutral	0,45	neutral	0,06	neutral	0,21	neutral	0,26	5	neutral	0,1	deleterious	0,86	neutral	-6	deleterious	0,66	medium_impact	-0,15	medium_impact	0,8	medium_impact	-0,61	0,14	0,8	17,43	20,8	N	0,36	N	0,92	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11283	11283	A	T	MI.17428	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	524	175	N	I	aAc/aTc	1,91	0,91	0	probably_damaging	0,96	neutral	0,41	neutral	4,52	deleterious	-4,21	deleterious	-5,01	medium_impact	2,25	neutral	0,75	neutral	0,52	deleterious	3,76	23,3	0,07	0,35	disease	0,73	disease	0,6	disease	0,54	disease	0,58	2	neutral	0,96	neutral	0,23	deleterious	1	deleterious	0,76	low_impact	-2,01	medium_impact	0,11	medium_impact	1,1	0,09	0,8	17,43	20,8	N	0,38	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11283	11283	A	C	MI.17429	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	524	175	N	T	aAc/aCc	1,91	0,91	0	possibly_damaging	0,74	neutral	0,38	neutral	4,55	neutral	-1,4	deleterious	-2,97	low_impact	1,29	neutral	0,75	neutral	0,65	deleterious	3,3	22,9	0,21	0,45	disease	0,52	neutral	0,36	neutral	0,28	neutral	0,38	2	neutral	0,76	neutral	0,32	neutral	-3	deleterious	0,69	low_impact	-1,14	medium_impact	0,08	medium_impact	0,15	0,23	0,8	17,43	20,8	N	0,36	N	0,78	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8507	8507	A	C	MI.1743	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	142	48	N	H	Aac/Cac	-6,58	0	0	possibly_damaging	0,46	neutral	0,57	neutral	1,95	neutral	-1,2	neutral	-2,4	low_impact	1,36	neutral	1	neutral	0,78	neutral	1,35	12,53	0,67759194	0,85	neutral	0,32	neutral	0,11	neutral	0,3	neutral	0,06	9	neutral	0,42	deleterious	0,56	neutral	-3	neutral	0,37	medium_impact	-0,69	medium_impact	0,36	medium_impact	0,07	0,71	0,85	NA	NA	N	0,38	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11284	11284	C	G	MI.17430	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	525	175	N	K	aaC/aaG	4,9	0,94	0	possibly_damaging	0,83	neutral	0,25	neutral	4,58	neutral	-1,94	deleterious	-3,12	medium_impact	2,59	neutral	0,72	neutral	0,35	deleterious	3,93	23,5	0,27	0,45	neutral	0,18	disease	0,58	disease	0,66	disease	0,72	4	neutral	0,88	neutral	0,21	NA	0	deleterious	0,69	low_impact	-1,37	medium_impact	-0,07	medium_impact	1,44	0,32	0,8	17,43	20,8	N	0,53	P	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11284	11284	C	A	MI.17431	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	525	175	N	K	aaC/aaA	4,9	0,94	0	possibly_damaging	0,83	neutral	0,25	neutral	4,58	neutral	-1,94	deleterious	-3,12	medium_impact	2,59	neutral	0,72	neutral	0,35	deleterious	4,43	24,2	0,27	0,45	neutral	0,18	disease	0,58	disease	0,66	disease	0,72	4	neutral	0,88	neutral	0,21	NA	0	deleterious	0,69	low_impact	-1,37	medium_impact	-0,07	medium_impact	1,44	0,32	0,8	17,43	20,8	N	0,53	P	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11285	11285	A	G	MI.17432	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	526	176	I	V	Att/Gtt	-4,78	0	0	benign	0,18	neutral	0,17	neutral	4,56	neutral	-0,75	neutral	-0,57	low_impact	1,74	neutral	0,76	neutral	0,73	deleterious	2,79	21,3	0,38	0,5	neutral	0,24	neutral	0,13	disease	0,56	neutral	0,31	4	neutral	0,8	deleterious	0,5	neutral	-6	deleterious	0,56	medium_impact	-0,1	medium_impact	-0,18	medium_impact	0,6	0,39	0,8	26,8	28,07	N	0,47	N	0,47	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11285	11285	A	T	MI.17433	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	526	176	I	F	Att/Ttt	-4,78	0	0	benign	0,03	neutral	1	neutral	4,87	neutral	1,18	neutral	0,9	neutral_impact	-0,69	neutral	0,72	neutral	0,98	neutral	1,51	13,37	0,16	0,45	neutral	0,37	neutral	0,24	neutral	0,23	neutral	0,44	1	neutral	0,03	deleterious	0,99	neutral	-6	deleterious	0,64	medium_impact	0,7	high_impact	1,88	low_impact	-1,81	0,52	0,8	26,8	28,07	N	0,3	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11285	11285	A	C	MI.17434	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	526	176	I	L	Att/Ctt	-4,78	0	0	benign	0,01	neutral	0,81	neutral	4,69	neutral	0,34	neutral	0,19	neutral_impact	-0,14	neutral	0,71	neutral	0,97	neutral	1,22	11,87	0,27	0,45	neutral	0,32	neutral	0,12	neutral	0,14	neutral	0,26	5	neutral	0,16	deleterious	0,9	neutral	-6	deleterious	0,58	medium_impact	1,16	medium_impact	0,56	low_impact	-1,26	0,48	0,8	26,8	28,07	N	0,43	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11286	11286	T	G	MI.17435	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	527	176	I	S	aTt/aGt	-2,24	0	0	benign	0,37	neutral	0,14	neutral	4,48	neutral	-2,42	neutral	-2,3	low_impact	1,34	neutral	0,78	neutral	0,72	deleterious	4,23	23,9	0,02	0,35	neutral	0,48	disease	0,5	disease	0,56	disease	0,63	3	neutral	0,84	neutral	0,39	neutral	-6	deleterious	0,7	medium_impact	-0,5	medium_impact	-0,24	medium_impact	0,2	0,19	0,8	26,8	28,07	N	0,32	N	0,54	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11286	11286	T	C	MI.17436	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	527	176	I	T	aTt/aCt	-2,24	0	0	benign	0,03	neutral	0,09	neutral	4,51	neutral	-1,48	neutral	-2	low_impact	0,87	neutral	0,68	neutral	0,85	deleterious	2,12	16,96	0,06	0,35	neutral	0,45	neutral	0,27	neutral	0,32	neutral	0,45	1	neutral	0,91	deleterious	0,53	neutral	-6	deleterious	0,67	medium_impact	0,7	medium_impact	-0,36	medium_impact	-0,27	0,2	0,8	26,8	28,07	N	0,48	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11286	11286	T	A	MI.17437	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	527	176	I	N	aTt/aAt	-2,24	0	0	possibly_damaging	0,7	neutral	0,05	neutral	4,45	deleterious	-3,65	deleterious	-3,07	medium_impact	2,23	neutral	0,69	neutral	0,5	deleterious	4,35	24,1	0,07	0,35	neutral	0,45	disease	0,59	disease	0,56	disease	0,69	4	neutral	0,96	neutral	0,18	NA	0	deleterious	0,72	low_impact	-1,06	medium_impact	-0,52	medium_impact	1,08	0,17	0,8	26,8	28,07	N	0,4	N	0,75	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11287	11287	T	A	MI.17438	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	528	176	I	M	atT/atA	3,06	0,15	0,01	benign	0,12	neutral	0,85	neutral	4,48	neutral	-2,34	neutral	0,31	neutral_impact	-0,08	neutral	0,7	neutral	0,85	neutral	0,98	10,54	0,24	0,45	disease	0,55	neutral	0,1	neutral	0,17	neutral	0,3	4	neutral	0,06	deleterious	0,87	neutral	-6	deleterious	0,65	medium_impact	0,1	medium_impact	0,62	low_impact	-1,21	0,58	0,8	26,8	28,07	N	0,4	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11287	11287	T	G	MI.17439	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	528	176	I	M	atT/atG	3,06	0,15	0,01	benign	0,12	neutral	0,85	neutral	4,48	neutral	-2,34	neutral	0,31	neutral_impact	-0,08	neutral	0,7	neutral	0,85	deleterious	0,63	8,35	0,24	0,45	disease	0,55	neutral	0,1	neutral	0,17	neutral	0,3	4	neutral	0,06	deleterious	0,87	neutral	-6	deleterious	0,65	medium_impact	0,1	medium_impact	0,62	low_impact	-1,21	0,58	0,8	26,8	28,07	N	0,39	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8507	8507	A	G	MI.1744	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	142	48	N	D	Aac/Gac	-6,58	0	0	benign	0,12	neutral	0,38	neutral	1,96	neutral	-0,79	deleterious	-2,58	low_impact	1,57	neutral	1	neutral	0,9	deleterious	0,86	9,8	0,73708172	0,85	neutral	0,28	neutral	0,16	neutral	0,4	neutral	0,13	7	neutral	0,56	deleterious	0,63	neutral	-6	neutral	0,18	medium_impact	0,07	medium_impact	0,17	medium_impact	0,25	0,69	0,85	NA	NA	N	0,47	N	0,47	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11288	11288	C	G	MI.17440	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	529	177	L	V	Cta/Gta	-10,78	0	0	benign	0,01	neutral	0,42	neutral	4,59	neutral	-1,08	neutral	-1,49	low_impact	1,84	neutral	0,85	neutral	0,71	neutral	1,36	12,58	0,33	0,5	neutral	0,33	neutral	0,25	neutral	0,32	neutral	0,46	1	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,15	medium_impact	1,16	medium_impact	0,12	medium_impact	0,69	0,44	0,8	26,58	26,6	N	0,4	N	0,15	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11288	11288	C	A	MI.17441	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	529	177	L	M	Cta/Ata	-10,78	0	0	benign	0,03	neutral	0,23	neutral	4,57	neutral	-1,8	neutral	-0,88	low_impact	0,88	neutral	0,77	neutral	0,93	deleterious	0,55	7,8	0,28	0,45	disease	0,52	neutral	0,2	neutral	0,18	neutral	0,31	4	neutral	0,76	deleterious	0,6	neutral	-6	neutral	0,16	medium_impact	0,7	medium_impact	-0,09	medium_impact	-0,26	0,42	0,8	26,58	26,6	N	0,47	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11289	11289	T	C	MI.17442	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	530	177	L	P	cTa/cCa	-3,86	0	0	benign	0,02	neutral	0,35	neutral	4,61	neutral	-0,45	deleterious	-4,15	neutral_impact	0,78	neutral	0,78	neutral	0,8	neutral	1,11	11,28	0,04	0,35	disease	0,72	disease	0,6	neutral	0,36	neutral	0,5	0	neutral	0,64	deleterious	0,67	neutral	-6	deleterious	0,56	medium_impact	0,87	medium_impact	0,05	medium_impact	-0,35	0,11	0,8	26,58	26,6	N	0,27	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11289	11289	T	A	MI.17443	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	530	177	L	Q	cTa/cAa	-3,86	0	0	possibly_damaging	0,55	neutral	0,28	neutral	4,63	neutral	-0,19	deleterious	-3,66	low_impact	1,75	neutral	0,73	neutral	0,42	deleterious	2,33	18,39	0,05	0,35	disease	0,65	disease	0,64	neutral	0,36	neutral	0,49	0	neutral	0,71	neutral	0,37	neutral	-3	deleterious	0,52	medium_impact	-0,8	medium_impact	-0,03	medium_impact	0,61	0,12	0,8	26,58	26,6	N	0,35	N	0,73	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11289	11289	T	G	MI.17444	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	530	177	L	R	cTa/cGa	-3,86	0	0	possibly_damaging	0,47	neutral	0,3	neutral	4,63	neutral	-0,24	deleterious	-3,8	medium_impact	2,99	neutral	0,7	neutral	0,35	deleterious	2,42	18,95	0,03	0,35	neutral	0,49	disease	0,73	neutral	0,5	disease	0,52	0	neutral	0,67	neutral	0,42	NA	0	deleterious	0,5	medium_impact	-0,67	medium_impact	0	medium_impact	1,83	0,11	0,8	26,58	26,6	N	0,35	N	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11291	11291	C	G	MI.17445	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	532	178	L	V	Cta/Gta	-5,01	0	0	benign	0,4	neutral	0,23	neutral	4,59	neutral	-0,91	neutral	-0,52	low_impact	1,57	neutral	0,75	neutral	0,99	neutral	1,36	12,57	0,32	0,5	neutral	0,25	neutral	0,19	neutral	0,23	neutral	0,38	2	neutral	0,73	neutral	0,42	neutral	-6	deleterious	0,62	medium_impact	-0,55	medium_impact	-0,09	medium_impact	0,43	0,36	0,8	17,21	12,29	P	0,53	P	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11291	11291	C	A	MI.17446	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	532	178	L	M	Cta/Ata	-5,01	0	0	probably_damaging	0,93	neutral	0,39	neutral	4,56	neutral	-2,58	neutral	-0,54	neutral_impact	0,7	neutral	0,74	neutral	0,98	deleterious	2,16	17,25	0,27	0,45	neutral	0,3	neutral	0,12	neutral	0,19	neutral	0,31	4	neutral	0,93	neutral	0,23	neutral	-2	deleterious	0,63	low_impact	-1,77	medium_impact	0,09	medium_impact	-0,43	0,4	0,8	17,21	12,29	N	0,52	P	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11292	11292	T	C	MI.17447	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	533	178	L	P	cTa/cCa	-3,17	0	0	probably_damaging	0,95	deleterious	0,02	neutral	4,57	neutral	-1,55	deleterious	-3,33	medium_impact	3,1	neutral	0,66	neutral	0,43	deleterious	2,65	20,5	0,03	0,35	neutral	0,34	disease	0,78	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,74	low_impact	-1,92	medium_impact	-0,75	medium_impact	1,94	0,13	0,8	17,21	12,29	N	0,36	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11292	11292	T	A	MI.17448	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	533	178	L	Q	cTa/cAa	-3,17	0	0	probably_damaging	0,95	deleterious	0,03	neutral	4,62	neutral	-0,41	deleterious	-2,92	medium_impact	3,1	neutral	0,74	neutral	0,56	deleterious	2,84	21,6	0,05	0,35	disease	0,59	disease	0,57	neutral	0,5	neutral	0,5	0	deleterious	0,99	neutral	0,04	deleterious	5	deleterious	0,71	low_impact	-1,92	medium_impact	-0,64	medium_impact	1,94	0,12	0,8	17,21	12,29	N	0,4	N	0,67	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11292	11292	T	G	MI.17449	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	533	178	L	R	cTa/cGa	-3,17	0	0	probably_damaging	0,93	deleterious	0,04	neutral	4,62	neutral	-0,39	deleterious	-3,06	medium_impact	3,44	neutral	0,71	neutral	0,49	deleterious	2,72	20,9	0,03	0,35	disease	0,57	disease	0,7	disease	0,64	disease	0,72	4	deleterious	0,99	neutral	0,06	deleterious	5	deleterious	0,76	low_impact	-1,77	medium_impact	-0,57	high_impact	2,28	0,15	0,8	17,21	12,29	N	0,41	N	0,8	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8507	8507	A	T	MI.1745	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	142	48	N	Y	Aac/Tac	-6,58	0	0	benign	0,38	neutral	1	neutral	1,92	neutral	-2,92	deleterious	-4,05	medium_impact	2,46	neutral	1	neutral	0,6	neutral	0,9	10,1	0,45194317	0,85	disease	0,53	neutral	0,26	neutral	0,33	neutral	0,14	7	neutral	0,38	deleterious	0,81	neutral	-3	neutral	0,4	medium_impact	-0,55	high_impact	1,98	medium_impact	1,01	0,61	0,85	NA	NA	N	0,28	N	0,56	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11294	11294	C	T	MI.17450	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	535	179	L	F	Ctc/Ttc	-12,39	0	0	probably_damaging	0,98	neutral	0,23	neutral	4,31	deleterious	-3,22	neutral	-1,32	neutral_impact	0,78	neutral	0,75	neutral	0,79	deleterious	2,84	21,6	0,16	0,45	neutral	0,35	neutral	0,36	neutral	0,23	neutral	0,47	1	deleterious	0,98	neutral	0,13	neutral	-2	deleterious	0,67	low_impact	-2,31	medium_impact	-0,09	medium_impact	-0,35	0,5	0,8	20,48	18,56	N	0,38	N	0,17	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11294	11294	C	G	MI.17451	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	535	179	L	V	Ctc/Gtc	-12,39	0	0	possibly_damaging	0,9	neutral	0,09	neutral	4,42	neutral	-1,38	neutral	-1,13	low_impact	1,64	neutral	0,8	neutral	0,57	deleterious	3,35	22,9	0,24	0,45	neutral	0,32	neutral	0,28	neutral	0,23	neutral	0,47	1	neutral	0,97	neutral	0,1	neutral	-3	deleterious	0,65	low_impact	-1,61	medium_impact	-0,36	medium_impact	0,5	0,52	0,8	20,48	18,56	N	0,46	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11294	11294	C	A	MI.17452	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	535	179	L	I	Ctc/Atc	-12,39	0	0	possibly_damaging	0,9	neutral	0,37	neutral	4,56	neutral	-0,42	neutral	-0,58	neutral_impact	0,74	neutral	0,76	neutral	0,98	deleterious	2,52	19,58	0,27	0,45	neutral	0,26	neutral	0,14	neutral	0,17	neutral	0,3	4	neutral	0,9	neutral	0,24	neutral	-3	deleterious	0,64	low_impact	-1,61	medium_impact	0,07	medium_impact	-0,39	0,55	0,8	20,48	18,56	N	0,51	P	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11295	11295	T	G	MI.17453	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	536	179	L	R	cTc/cGc	-7,09	0	0	probably_damaging	0,98	deleterious	0,01	neutral	4,29	deleterious	-4,11	deleterious	-3,33	medium_impact	3,34	neutral	0,63	damaging	0,13	deleterious	4,14	23,8	0,02	0,35	disease	0,57	disease	0,76	disease	0,64	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-2,31	medium_impact	-0,92	high_impact	2,18	0,22	0,8	20,48	18,56	N	0,26	N	0,87	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11295	11295	T	A	MI.17454	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	536	179	L	H	cTc/cAc	-7,09	0	0	probably_damaging	1	deleterious	0,01	neutral	4,28	deleterious	-4,68	deleterious	-3,33	medium_impact	2,98	neutral	0,74	neutral	0,3	deleterious	4,22	23,9	0,04	0,35	disease	0,67	disease	0,68	disease	0,59	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,76	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,82	0,18	0,8	20,48	18,56	N	0,3	N	0,82	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11295	11295	T	C	MI.17455	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	536	179	L	P	cTc/cCc	-7,09	0	0	probably_damaging	1	deleterious	0	neutral	4,32	neutral	-2,97	deleterious	-3,71	medium_impact	2,79	neutral	0,63	damaging	0,19	deleterious	3,93	23,5	0,02	0,35	disease	0,68	disease	0,8	disease	0,65	disease	0,71	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	medium_impact	1,63	0,1	0,8	20,48	18,56	N	0,26	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11297	11297	A	T	MI.17456	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	538	180	T	S	Act/Tct	-11,24	0	0	benign	0,03	neutral	1	neutral	4,68	neutral	-0,17	neutral	0,18	neutral_impact	0	neutral	0,76	neutral	0,98	deleterious	0,08	3,42	0,39	0,5	neutral	0,24	neutral	0,21	neutral	0,14	neutral	0,36	3	neutral	0,03	deleterious	0,99	neutral	-6	neutral	0,27	medium_impact	0,7	high_impact	1,88	low_impact	-1,13	0,5	0,8	36,17	34,14	N	0,4	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11297	11297	A	C	MI.17457	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	538	180	T	P	Act/Cct	-11,24	0	0	possibly_damaging	0,72	neutral	0,29	neutral	4,59	neutral	-1,91	neutral	-0,52	neutral_impact	0,61	neutral	0,73	neutral	0,98	deleterious	1,93	15,78	0,09	0,35	disease	0,74	disease	0,66	neutral	0,3	disease	0,53	1	neutral	0,79	neutral	0,29	neutral	-3	deleterious	0,7	low_impact	-1,1	medium_impact	-0,02	medium_impact	-0,52	0,35	0,8	36,17	34,14	N	0,4	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11297	11297	A	G	MI.17458	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	538	180	T	A	Act/Gct	-11,24	0	0	benign	0,02	neutral	0,71	neutral	4,68	neutral	0,94	neutral	-0,59	low_impact	1,07	neutral	0,82	neutral	0,9	deleterious	0,55	7,83	0,3	0,45	neutral	0,48	neutral	0,25	neutral	0,29	neutral	0,42	2	neutral	0,26	deleterious	0,85	neutral	-6	neutral	0,37	medium_impact	0,87	medium_impact	0,42	medium_impact	-0,07	0,28	0,8	36,17	34,14	N	0,32	N	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11298	11298	C	A	MI.17459	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	539	180	T	N	aCt/aAt	-0,17	0	0	benign	0,03	neutral	0,59	neutral	4,67	neutral	-1,06	neutral	-0,01	neutral_impact	0,64	neutral	0,72	neutral	0,95	deleterious	0,32	5,92	0,28	0,45	disease	0,55	neutral	0,4	neutral	0,17	disease	0,59	2	neutral	0,37	deleterious	0,78	neutral	-6	neutral	0,18	medium_impact	0,7	medium_impact	0,29	medium_impact	-0,49	0,5	0,8	36,17	34,14	N	0,41	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8508	8508	A	G	MI.1746	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	143	48	N	S	aAc/aGc	-5,66	0	0	benign	0,05	neutral	0,66	neutral	2,03	neutral	0,35	neutral	-1,69	low_impact	0,96	neutral	1	neutral	0,86	neutral	-0,07	1,95	0,70300388	0,85	neutral	0,15	neutral	0,14	neutral	0,35	neutral	0,11	8	neutral	0,27	deleterious	0,81	neutral	-6	neutral	0,12	medium_impact	0,46	medium_impact	0,45	medium_impact	-0,28	0,45	0,85	NA	NA	N	0,36	N	0,33	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11298	11298	C	G	MI.17460	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	539	180	T	S	aCt/aGt	-0,17	0	0	benign	0,03	neutral	1	neutral	4,68	neutral	-0,17	neutral	0,18	neutral_impact	0	neutral	0,76	neutral	0,98	deleterious	0,29	5,6	0,39	0,5	neutral	0,24	neutral	0,21	neutral	0,14	neutral	0,36	3	neutral	0,03	deleterious	0,99	neutral	-6	neutral	0,27	medium_impact	0,7	high_impact	1,88	low_impact	-1,13	0,5	0,8	36,17	34,14	N	0,35	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11298	11298	C	T	MI.17461	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	539	180	T	I	aCt/aTt	-0,17	0	0	possibly_damaging	0,49	neutral	0,32	neutral	4,66	neutral	-1,6	neutral	-1,64	neutral_impact	0,78	neutral	0,79	neutral	0,7	deleterious	3,57	23,2	0,17	0,45	disease	0,59	neutral	0,43	neutral	0,31	disease	0,62	2	neutral	0,65	neutral	0,42	neutral	-3	deleterious	0,63	medium_impact	-0,7	medium_impact	0,02	medium_impact	-0,35	0,43	0,8	36,17	34,14	N	0,37	N	0,6	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11300	11300	C	G	MI.17462	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	541	181	L	V	Ctc/Gtc	-4,32	0	0	benign	0,12	neutral	0,13	neutral	4,54	neutral	-1,39	neutral	-0,71	neutral_impact	0,78	neutral	0,78	neutral	0,68	deleterious	3,37	22,9	0,41	0,5	neutral	0,29	neutral	0,28	neutral	0,35	neutral	0,44	1	neutral	0,85	deleterious	0,51	neutral	-6	deleterious	0,65	medium_impact	0,1	medium_impact	-0,26	medium_impact	-0,35	0,29	0,8	28,76	24,53	N	0,41	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11300	11300	C	A	MI.17463	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	541	181	L	I	Ctc/Atc	-4,32	0	0	benign	0,12	neutral	0,22	neutral	4,51	neutral	-2,7	neutral	-0,38	neutral_impact	0,52	neutral	0,79	neutral	0,98	deleterious	2,77	21,2	0,33	0,5	neutral	0,22	neutral	0,3	neutral	0,18	neutral	0,45	1	neutral	0,75	deleterious	0,55	neutral	-6	deleterious	0,64	medium_impact	0,1	medium_impact	-0,11	medium_impact	-0,61	0,49	0,8	28,76	24,53	N	0,54	P	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11300	11300	C	T	MI.17464	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	541	181	L	F	Ctc/Ttc	-4,32	0	0	probably_damaging	0,94	neutral	0,6	neutral	4,51	neutral	-2,48	neutral	1,27	neutral_impact	0,74	neutral	0,75	neutral	0,97	deleterious	2,4	18,81	0,36	0,5	neutral	0,49	neutral	0,27	neutral	0,18	neutral	0,41	2	neutral	0,93	neutral	0,33	neutral	-2	deleterious	0,68	low_impact	-1,84	medium_impact	0,3	medium_impact	-0,39	0,38	0,8	28,76	24,53	N	0,4	N	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11301	11301	T	A	MI.17465	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	542	181	L	H	cTc/cAc	-0,4	0	0	probably_damaging	0,98	neutral	0,2	neutral	4,51	neutral	-2,61	neutral	-0,16	medium_impact	2,04	neutral	0,77	neutral	0,96	deleterious	2,77	21,2	0,1	0,4	disease	0,7	disease	0,58	neutral	0,3	disease	0,52	0	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,75	low_impact	-2,31	medium_impact	-0,14	medium_impact	0,89	0,12	0,8	28,76	24,53	N	0,43	N	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11301	11301	T	C	MI.17466	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	542	181	L	P	cTc/cCc	-0,4	0	0	probably_damaging	0,98	neutral	0,07	neutral	4,5	neutral	-2,89	deleterious	-2,56	low_impact	0,88	damaging	0,57	neutral	0,44	deleterious	3,84	23,4	0,04	0,35	disease	0,71	disease	0,81	disease	0,57	disease	0,74	5	deleterious	0,99	neutral	0,05	neutral	-2	deleterious	0,82	low_impact	-2,31	medium_impact	-0,43	medium_impact	-0,26	0,16	0,8	28,76	24,53	N	0,31	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11301	11301	T	G	MI.17467	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	542	181	L	R	cTc/cGc	-0,4	0	0	probably_damaging	0,96	neutral	0,08	neutral	4,57	neutral	-0,98	neutral	-1,91	medium_impact	2,04	neutral	0,64	neutral	0,48	deleterious	4,12	23,8	0,06	0,35	disease	0,63	disease	0,76	disease	0,53	disease	0,67	3	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,79	low_impact	-2,01	medium_impact	-0,39	medium_impact	0,89	0,17	0,8	28,76	24,53	N	0,36	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11303	11303	A	T	MI.17468	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	544	182	T	S	Act/Tct	-5,01	0	0	benign	0,02	neutral	0,42	neutral	2,3	neutral	-0,17	neutral	-0,25	neutral_impact	-0,58	neutral	0,77	neutral	0,98	neutral	-0,47	0,26	0,46	0,55	neutral	0,38	neutral	0,12	neutral	0,18	neutral	0,31	4	neutral	0,56	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	0,87	medium_impact	0,12	low_impact	-1,7	0,57	0,8	33,12	36,91	N	0,51	P	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11303	11303	A	C	MI.17469	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	544	182	T	P	Act/Cct	-5,01	0	0	possibly_damaging	0,55	neutral	0,2	neutral	2,22	neutral	-1,81	neutral	-1,3	low_impact	0,95	neutral	0,7	neutral	0,67	neutral	1,76	14,77	0,09	0,35	disease	0,61	disease	0,71	disease	0,51	disease	0,6	2	neutral	0,79	neutral	0,33	neutral	-3	deleterious	0,65	medium_impact	-0,8	medium_impact	-0,14	medium_impact	-0,19	0,36	0,8	33,12	36,91	N	0,32	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8508	8508	A	C	MI.1747	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	143	48	N	T	aAc/aCc	-5,66	0	0	benign	0,05	neutral	0,58	neutral	2,08	neutral	0,92	neutral	-2,17	neutral_impact	0,44	neutral	1	neutral	0,95	deleterious	0,34	6,09	0,74487615	0,85	neutral	0,28	neutral	0,26	neutral	0,25	neutral	0,23	5	neutral	0,36	deleterious	0,77	neutral	-6	neutral	0,15	medium_impact	0,46	medium_impact	0,37	medium_impact	-0,72	0,59	0,85	NA	NA	N	0,36	N	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11303	11303	A	G	MI.17470	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	544	182	T	A	Act/Gct	-5,01	0	0	benign	0,12	neutral	0,5	neutral	2,34	neutral	0,48	neutral	-0,77	neutral_impact	0,6	neutral	0,76	neutral	0,86	neutral	-0,32	0,61	0,31	0,45	neutral	0,28	neutral	0,2	neutral	0,32	neutral	0,37	3	neutral	0,42	deleterious	0,69	neutral	-6	neutral	0,25	medium_impact	0,1	medium_impact	0,2	medium_impact	-0,53	0,33	0,8	33,12	36,91	N	0,36	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11304	11304	C	T	MI.17471	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	545	182	T	I	aCt/aTt	-1,09	0	0	benign	0,12	neutral	0,39	neutral	2,26	neutral	-1,32	neutral	-1,2	neutral_impact	-0,69	neutral	0,75	neutral	0,77	deleterious	1,88	15,47	0,22	0,45	neutral	0,18	neutral	0,4	neutral	0,21	neutral	0,44	1	neutral	0,55	deleterious	0,64	neutral	-6	deleterious	0,53	medium_impact	0,1	medium_impact	0,09	low_impact	-1,81	0,47	0,8	33,12	36,91	N	0,4	N	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11304	11304	C	A	MI.17472	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	545	182	T	N	aCt/aAt	-1,09	0	0	benign	0,38	neutral	0,32	neutral	2,27	neutral	-0,6	neutral	-0,68	neutral_impact	0,14	neutral	0,7	neutral	0,92	deleterious	0,28	5,49	0,39	0,5	disease	0,56	neutral	0,35	neutral	0,2	disease	0,58	2	neutral	0,62	deleterious	0,47	neutral	-6	neutral	0,4	medium_impact	-0,52	medium_impact	0,02	medium_impact	-0,99	0,48	0,8	33,12	36,91	N	0,46	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11304	11304	C	G	MI.17473	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	545	182	T	S	aCt/aGt	-1,09	0	0	benign	0,02	neutral	0,42	neutral	2,3	neutral	-0,17	neutral	-0,25	neutral_impact	-0,58	neutral	0,77	neutral	0,98	neutral	-0,26	0,83	0,46	0,55	neutral	0,38	neutral	0,12	neutral	0,18	neutral	0,31	4	neutral	0,56	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	0,87	medium_impact	0,12	low_impact	-1,7	0,57	0,8	33,12	36,91	N	0,53	P	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11306	11306	G	C	MI.17474	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	547	183	A	P	Gcc/Ccc	-5,7	0	0	possibly_damaging	0,55	neutral	0,28	neutral	2,02	deleterious	-3,6	neutral	-0,19	neutral_impact	0,52	neutral	0,73	neutral	0,75	neutral	1,74	14,64	0,07	0,35	disease	0,74	disease	0,52	neutral	0,24	neutral	0,47	1	neutral	0,71	neutral	0,37	neutral	-3	deleterious	0,57	medium_impact	-0,8	medium_impact	-0,03	medium_impact	-0,61	0,39	0,8	25,05	16,68	N	0,42	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11306	11306	G	T	MI.17475	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	547	183	A	S	Gcc/Tcc	-5,7	0	0	benign	0,02	neutral	0,49	neutral	2,1	neutral	-2,25	neutral	0,32	neutral_impact	-0,44	neutral	0,78	neutral	0,93	neutral	-0,74	0,06	0,37	0,5	neutral	0,27	neutral	0,19	neutral	0,13	neutral	0,35	3	neutral	0,49	deleterious	0,74	neutral	-6	neutral	0,11	medium_impact	0,87	medium_impact	0,19	low_impact	-1,56	0,4	0,8	25,05	16,68	N	0,44	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11306	11306	G	A	MI.17476	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	547	183	A	T	Gcc/Acc	-5,7	0	0	benign	0,01	neutral	0,45	neutral	2,06	neutral	-2,59	neutral	0,08	neutral_impact	-0,32	neutral	0,82	neutral	1	deleterious	0,17	4,32	0,29	0,45	neutral	0,41	neutral	0,18	neutral	0,13	neutral	0,36	3	neutral	0,54	deleterious	0,72	neutral	-6	neutral	0,23	medium_impact	1,16	medium_impact	0,15	low_impact	-1,44	0,6	0,8	25,05	16,68	N	0,48	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11307	11307	C	A	MI.17477	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	548	183	A	D	gCc/gAc	-5,93	0	0	benign	0,02	neutral	0,26	neutral	2,03	deleterious	-3,37	neutral	-0,67	neutral_impact	-0,06	neutral	0,75	neutral	0,69	deleterious	0,59	8,06	0,04	0,35	disease	0,68	disease	0,53	neutral	0,48	neutral	0,49	0	neutral	0,73	deleterious	0,62	neutral	-6	deleterious	0,46	medium_impact	0,87	medium_impact	-0,05	low_impact	-1,19	0,24	0,8	25,05	16,68	N	0,32	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11307	11307	C	G	MI.17478	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	548	183	A	G	gCc/gGc	-5,93	0	0	benign	0,01	neutral	0,38	neutral	2,08	neutral	-1,98	neutral	-1,03	neutral_impact	0,49	neutral	0,78	neutral	0,76	deleterious	0,49	7,34	0,36	0,5	disease	0,67	neutral	0,27	neutral	0,29	disease	0,55	1	neutral	0,61	deleterious	0,69	neutral	-6	neutral	0,27	medium_impact	1,16	medium_impact	0,08	medium_impact	-0,64	0,56	0,8	25,05	16,68	N	0,33	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11307	11307	C	T	MI.17479	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	548	183	A	V	gCc/gTc	-5,93	0	0	benign	0,26	neutral	0,51	neutral	2,08	neutral	-2,31	neutral	-0,55	neutral_impact	0,74	neutral	0,79	neutral	0,92	neutral	1,1	11,23	0,25	0,45	neutral	0,4	neutral	0,25	neutral	0,29	neutral	0,45	1	neutral	0,39	deleterious	0,63	neutral	-6	neutral	0,36	medium_impact	-0,29	medium_impact	0,21	medium_impact	-0,39	0,73	0,85	25,05	16,68	N	0,34	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8508	8508	A	T	MI.1748	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	143	48	N	I	aAc/aTc	-5,66	0	0	benign	0,05	neutral	0,45	neutral	1,92	neutral	-2,6	deleterious	-4,25	low_impact	1,57	neutral	1	neutral	0,87	deleterious	1,96	15,94	0,52090386	0,85	neutral	0,46	neutral	0,2	neutral	0,39	neutral	0,14	7	neutral	0,51	deleterious	0,7	neutral	-6	neutral	0,19	medium_impact	0,46	medium_impact	0,24	medium_impact	0,25	0,53	0,85	NA	NA	N	0,46	N	0,7	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11309	11309	C	G	MI.17480	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	550	184	Q	E	Caa/Gaa	-6,16	0	0	benign	0,18	neutral	0,28	neutral	2,29	neutral	-0,3	neutral	-0,62	neutral_impact	0,1	neutral	0,81	neutral	0,95	neutral	-0,16	1,3	0,29	0,45	neutral	0,23	neutral	0,46	neutral	0,35	neutral	0,44	1	neutral	0,67	deleterious	0,55	neutral	-6	neutral	0,17	medium_impact	-0,1	medium_impact	-0,03	low_impact	-1,03	0,33	0,8	31,59	22,1	N	0,38	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11309	11309	C	A	MI.17481	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	550	184	Q	K	Caa/Aaa	-6,16	0	0	benign	0,01	neutral	0,29	neutral	2,28	neutral	-0,48	neutral	-0,44	neutral_impact	-0,26	neutral	0,81	neutral	0,9	deleterious	0,48	7,3	0,26	0,45	neutral	0,23	neutral	0,48	neutral	0,36	neutral	0,44	1	neutral	0,7	deleterious	0,64	neutral	-6	neutral	0,15	medium_impact	1,16	medium_impact	-0,02	low_impact	-1,38	0,23	0,8	31,59	22,1	N	0,36	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11310	11310	A	C	MI.17482	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	551	184	Q	P	cAa/cCa	-0,86	0	0	benign	0,01	neutral	0,24	neutral	2,25	neutral	-0,74	neutral	-0,08	neutral_impact	0,03	neutral	0,74	neutral	0,93	neutral	-1,39	0	0,13	0,4	disease	0,52	neutral	0,25	neutral	0,43	neutral	0,36	3	neutral	0,75	deleterious	0,62	neutral	-6	neutral	0,19	medium_impact	1,16	medium_impact	-0,08	low_impact	-1,1	0,23	0,8	31,59	22,1	N	0,48	N	0,85	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11310	11310	A	T	MI.17483	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	551	184	Q	L	cAa/cTa	-0,86	0	0	benign	0,26	neutral	0,66	neutral	2,23	neutral	-1,28	neutral	-1,91	neutral_impact	-0,75	neutral	0,77	neutral	0,72	deleterious	0,44	6,95	0,11	0,4	neutral	0,4	disease	0,5	neutral	0,36	neutral	0,45	1	neutral	0,24	deleterious	0,7	neutral	-6	neutral	0,2	medium_impact	-0,29	medium_impact	0,36	low_impact	-1,87	0,12	0,8	31,59	22,1	N	0,22	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11310	11310	A	G	MI.17484	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	551	184	Q	R	cAa/cGa	-0,86	0	0	benign	0,01	neutral	0,35	neutral	2,24	neutral	-1,04	neutral	-1,02	neutral_impact	0,42	neutral	0,81	neutral	0,73	deleterious	0,3	5,7	0,36	0,5	neutral	0,32	disease	0,52	neutral	0,44	disease	0,52	0	neutral	0,64	deleterious	0,67	neutral	-6	neutral	0,18	medium_impact	1,16	medium_impact	0,05	medium_impact	-0,71	0,11	0,8	31,59	22,1	N	0,33	N	0,03	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11311	11311	A	C	MI.17485	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	552	184	Q	H	caA/caC	-0,4	0	0	benign	0,01	neutral	0,54	neutral	2,22	neutral	-1,52	neutral	-1,34	neutral_impact	0,58	neutral	0,79	neutral	0,92	deleterious	0,48	7,26	0,2	0,45	neutral	0,29	neutral	0,37	neutral	0,32	neutral	0,45	1	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,42	medium_impact	1,16	medium_impact	0,24	medium_impact	-0,55	0,29	0,8	31,59	22,1	N	0,3	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11311	11311	A	T	MI.17486	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	552	184	Q	H	caA/caT	-0,4	0	0	benign	0,01	neutral	0,54	neutral	2,22	neutral	-1,52	neutral	-1,34	neutral_impact	0,58	neutral	0,79	neutral	0,92	deleterious	0,6	8,19	0,2	0,45	neutral	0,29	neutral	0,37	neutral	0,32	neutral	0,45	1	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,42	medium_impact	1,16	medium_impact	0,24	medium_impact	-0,55	0,29	0,8	31,59	22,1	N	0,3	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11312	11312	G	A	MI.17487	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	553	185	E	K	Gaa/Aaa	-9,62	0	0	benign	0,01	neutral	0,91	neutral	4,62	neutral	-1,06	neutral	-0,04	neutral_impact	-0,37	neutral	0,81	neutral	0,66	deleterious	0,42	6,79	0,1	0,4	neutral	0,27	neutral	0,27	neutral	0,41	neutral	0,42	2	neutral	0,07	deleterious	0,95	neutral	-6	neutral	0,18	medium_impact	1,16	medium_impact	0,77	low_impact	-1,49	0,57	0,8	30,94	35,44	N	0,25	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11312	11312	G	C	MI.17488	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	553	185	E	Q	Gaa/Caa	-9,62	0	0	benign	0,26	neutral	0,69	neutral	4,65	neutral	-0,66	neutral	0,17	neutral_impact	-0,64	neutral	0,76	neutral	0,8	neutral	-0,38	0,42	0,55	0,6	neutral	0,33	neutral	0,13	neutral	0,2	neutral	0,28	4	neutral	0,22	deleterious	0,72	neutral	-6	neutral	0,26	medium_impact	-0,29	medium_impact	0,4	low_impact	-1,76	0,56	0,8	30,94	35,44	N	0,35	N	0,42	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11313	11313	A	T	MI.17489	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	554	185	E	V	gAa/gTa	-5,24	0	0	benign	0,34	neutral	0,67	neutral	4,63	neutral	-2,01	neutral	0,31	neutral_impact	-0,28	neutral	0,8	neutral	0,82	deleterious	0,13	3,93	0,22	0,45	neutral	0,44	neutral	0,18	neutral	0,4	neutral	0,34	3	neutral	0,27	deleterious	0,67	neutral	-6	neutral	0,29	medium_impact	-0,45	medium_impact	0,37	low_impact	-1,4	0,42	0,8	30,94	35,44	N	0,27	N	0,49	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8509	8509	C	G	MI.1749	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	144	48	N	K	aaC/aaG	-1,03	0	0	benign	0,09	neutral	0,64	neutral	2,04	neutral	0,57	neutral	-1,96	neutral_impact	-0,04	neutral	0,99	neutral	0,92	deleterious	0,84	9,72	0,78510221	0,85	neutral	0,17	neutral	0,22	neutral	0,28	neutral	0,17	7	neutral	0,27	deleterious	0,78	neutral	-6	neutral	0,17	medium_impact	0,2	medium_impact	0,43	low_impact	-1,13	0,69	0,85	NA	NA	N	0,42	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11313	11313	A	C	MI.17490	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	554	185	E	A	gAa/gCa	-5,24	0	0	benign	0,12	neutral	1	neutral	4,69	neutral	-0,6	neutral	0,19	neutral_impact	-0,42	neutral	0,78	neutral	0,94	neutral	-0,77	0,05	0,36	0,5	neutral	0,19	neutral	0,11	neutral	0,38	neutral	0,3	4	neutral	0,12	deleterious	0,94	neutral	-6	neutral	0,12	medium_impact	0,1	high_impact	1,88	low_impact	-1,54	0,28	0,8	30,94	35,44	N	0,29	N	0,28	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11313	11313	A	G	MI.17491	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	554	185	E	G	gAa/gGa	-5,24	0	0	benign	0,18	neutral	0,57	neutral	4,61	neutral	-1,35	neutral	-1,12	neutral_impact	-0,14	neutral	0,79	neutral	0,64	deleterious	0,42	6,75	0,32	0,5	neutral	0,45	neutral	0,16	neutral	0,47	neutral	0,31	4	neutral	0,32	deleterious	0,7	neutral	-6	neutral	0,15	medium_impact	-0,1	medium_impact	0,27	low_impact	-1,26	0,34	0,8	30,94	35,44	N	0,27	N	0,44	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11314	11314	A	T	MI.17492	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	555	185	E	D	gaA/gaT	-0,4	0	0,01	benign	0,01	neutral	0,64	neutral	4,59	neutral	-0,78	neutral	-0,5	neutral_impact	0,12	neutral	0,74	neutral	0,76	deleterious	0,04	2,95	0,6	0,65	neutral	0,36	neutral	0,16	neutral	0,31	neutral	0,29	4	neutral	0,34	deleterious	0,82	neutral	-6	neutral	0,13	medium_impact	1,16	medium_impact	0,34	low_impact	-1,01	0,63	0,8	30,94	35,44	N	0,36	N	0,41	polymorphism	1	0,01	rs386829128	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11314	11314	A	C	MI.17493	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	555	185	E	D	gaA/gaC	-0,4	0	0,01	benign	0,01	neutral	0,64	neutral	4,59	neutral	-0,78	neutral	-0,5	neutral_impact	0,12	neutral	0,74	neutral	0,76	deleterious	-0,06	2,02	0,6	0,65	neutral	0,36	neutral	0,16	neutral	0,31	neutral	0,29	4	neutral	0,34	deleterious	0,82	neutral	-6	neutral	0,13	medium_impact	1,16	medium_impact	0,34	low_impact	-1,01	0,63	0,8	30,94	35,44	N	0,36	N	0,41	polymorphism	1	0,01	rs386829128	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11315	11315	C	G	MI.17494	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	556	186	L	V	Cta/Gta	-8,24	0	0,01	possibly_damaging	0,53	neutral	0,44	neutral	4,62	neutral	-1,87	neutral	-1	neutral_impact	0,79	neutral	0,78	neutral	0,85	deleterious	1,95	15,89	0,43	0,55	neutral	0,36	neutral	0,21	neutral	0,37	neutral	0,36	3	neutral	0,56	neutral	0,46	neutral	-3	deleterious	0,66	medium_impact	-0,77	medium_impact	0,14	medium_impact	-0,34	0,21	0,8	13,73	12,89	N	0,35	N	0,16	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11315	11315	C	A	MI.17495	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	556	186	L	M	Cta/Ata	-8,24	0	0,01	benign	0,4	neutral	0,31	neutral	4,59	neutral	-2,75	neutral	-0,42	neutral_impact	0,69	neutral	0,77	neutral	0,98	deleterious	2,41	18,87	0,37	0,5	neutral	0,45	neutral	0,14	neutral	0,23	neutral	0,31	4	neutral	0,64	neutral	0,46	neutral	-6	deleterious	0,67	medium_impact	-0,55	medium_impact	0,01	medium_impact	-0,44	0,51	0,8	13,73	12,89	N	0,45	N	0,49	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11316	11316	T	A	MI.17496	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	557	186	L	Q	cTa/cAa	-11,47	0	0	probably_damaging	0,93	neutral	0,35	neutral	4,5	deleterious	-4,46	neutral	-1,93	neutral_impact	-0,27	neutral	0,76	neutral	0,86	deleterious	2,9	21,9	0,14	0,4	disease	0,76	disease	0,52	neutral	0,3	disease	0,52	0	neutral	0,94	neutral	0,21	neutral	-2	deleterious	0,77	low_impact	-1,77	medium_impact	0,05	low_impact	-1,39	0,15	0,8	13,73	12,89	N	0,32	N	0,92	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11316	11316	T	C	MI.17497	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	557	186	L	P	cTa/cCa	-11,47	0	0	probably_damaging	0,95	neutral	0,29	neutral	4,49	deleterious	-4,02	deleterious	-2,75	neutral_impact	-0,69	neutral	0,75	neutral	0,8	deleterious	2,72	20,9	0,08	0,35	disease	0,8	disease	0,66	neutral	0,33	disease	0,57	1	neutral	0,96	neutral	0,17	neutral	-2	deleterious	0,82	low_impact	-1,92	medium_impact	-0,02	low_impact	-1,81	0,08	0,8	13,73	12,89	N	0,32	N	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11316	11316	T	G	MI.17498	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	557	186	L	R	cTa/cGa	-11,47	0	0	probably_damaging	0,93	neutral	0,32	neutral	4,51	deleterious	-4,24	neutral	-2,29	low_impact	1,54	neutral	0,67	neutral	0,39	deleterious	2,92	21,9	0,09	0,4	disease	0,74	disease	0,73	disease	0,53	disease	0,65	3	neutral	0,94	neutral	0,2	neutral	-2	deleterious	0,82	low_impact	-1,77	medium_impact	0,02	medium_impact	0,4	0,1	0,8	13,73	12,89	N	0,29	N	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11318	11318	T	A	MI.17499	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	559	187	S	T	Tca/Aca	-5,24	0	0,01	benign	0	neutral	0,42	neutral	4,64	neutral	-1,24	neutral	0,11	neutral_impact	-0,06	neutral	0,77	neutral	1	neutral	-0,16	1,35	0,52	0,6	neutral	0,3	neutral	0,14	neutral	0,2	neutral	0,27	5	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,09	high_impact	2,1	medium_impact	0,12	low_impact	-1,19	0,5	0,8	30,72	19,66	N	0,49	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8608	8608	C	G	MI.175	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	82	28	P	A	Cct/Gct	-10,98	0	0	benign	0,18	neutral	0,22	neutral	4,47	neutral	2,52	neutral	0,89	neutral_impact	-1,1	neutral	0,89	neutral	0,93	neutral	-0,75	0,06	0,38	0,65	neutral	0,29	neutral	0,09	neutral	0,27	neutral	0,29	4	neutral	0,74	deleterious	0,52	neutral	-6	neutral	0,23	medium_impact	-0,13	medium_impact	-0,02	low_impact	-2,04	0,78	0,9	31,86	20,94	N	0,47	N	0,35	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8509	8509	C	A	MI.1750	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	144	48	N	K	aaC/aaA	-1,03	0	0	benign	0,09	neutral	0,64	neutral	2,04	neutral	0,57	neutral	-1,96	neutral_impact	-0,04	neutral	0,99	neutral	0,92	neutral	1,33	12,4	0,78510221	0,85	neutral	0,17	neutral	0,22	neutral	0,28	neutral	0,17	7	neutral	0,27	deleterious	0,78	neutral	-6	neutral	0,17	medium_impact	0,2	medium_impact	0,43	low_impact	-1,13	0,69	0,85	NA	NA	N	0,42	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11318	11318	T	C	MI.17500	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	559	187	S	P	Tca/Cca	-5,24	0	0,01	benign	0	neutral	0,23	neutral	4,59	neutral	-1,4	neutral	0,02	neutral_impact	0,74	neutral	0,78	neutral	1	deleterious	0,46	7,12	0,23	0,45	neutral	0,42	disease	0,63	neutral	0,23	neutral	0,43	1	neutral	0,77	deleterious	0,62	neutral	-6	neutral	0,19	high_impact	2,1	medium_impact	-0,09	medium_impact	-0,39	0,16	0,8	30,72	19,66	N	0,46	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11318	11318	T	G	MI.17501	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	559	187	S	A	Tca/Gca	-5,24	0	0,01	benign	0	neutral	0,51	neutral	4,66	neutral	-0,3	neutral	-0,37	low_impact	0,84	neutral	0,8	neutral	0,88	neutral	-0,26	0,83	0,46	0,55	neutral	0,33	neutral	0,24	neutral	0,31	neutral	0,44	1	neutral	0,49	deleterious	0,76	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,21	medium_impact	-0,3	0,25	0,8	30,72	19,66	N	0,35	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11319	11319	C	T	MI.17502	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	560	187	S	L	tCa/tTa	-10,32	0	0	benign	0	neutral	0,76	neutral	4,73	neutral	-2,16	neutral	0,3	neutral_impact	-1,01	neutral	0,71	neutral	0,97	deleterious	0,06	3,16	0,21	0,45	neutral	0,19	neutral	0,27	neutral	0,23	neutral	0,43	1	neutral	0,24	deleterious	0,88	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	0,48	low_impact	-2,13	0,23	0,8	30,72	19,66	N	0,41	N	0,38	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11319	11319	C	G	MI.17503	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	560	187	S	W	tCa/tGa	-10,32	0	0	possibly_damaging	0,59	neutral	0,19	neutral	4,56	deleterious	-5,68	neutral	-1,66	low_impact	1,11	neutral	0,77	neutral	0,39	neutral	1,33	12,4	0,1	0,4	disease	0,77	disease	0,7	disease	0,51	disease	0,58	2	neutral	0,81	neutral	0,3	neutral	-3	deleterious	0,56	medium_impact	-0,87	medium_impact	-0,15	medium_impact	-0,03	0,11	0,8	30,72	19,66	N	0,28	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11321	11321	A	G	MI.17504	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	562	188	N	D	Aac/Gac	-12,62	0	0	benign	0,01	neutral	0,66	neutral	4,55	neutral	-0,91	neutral	-0,95	neutral_impact	0,56	neutral	0,79	neutral	0,98	deleterious	0,31	5,76	0,89	0,9	disease	0,52	neutral	0,34	neutral	0,45	neutral	0,34	3	neutral	0,33	deleterious	0,83	neutral	-6	neutral	0,13	medium_impact	1,16	medium_impact	0,36	medium_impact	-0,57	0,19	0,8	29,41	21,06	N	0,33	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11321	11321	A	C	MI.17505	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	562	188	N	H	Aac/Cac	-12,62	0	0	possibly_damaging	0,68	neutral	0,46	neutral	4,47	neutral	-2,81	neutral	-0,99	low_impact	1,14	neutral	0,74	neutral	0,84	deleterious	0,65	8,47	0,73	0,75	disease	0,57	neutral	0,39	neutral	0,31	disease	0,62	2	neutral	0,67	neutral	0,39	neutral	-3	deleterious	0,54	low_impact	-1,03	medium_impact	0,16	medium_impact	0	0,04	0,8	29,41	21,06	N	0,36	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11321	11321	A	T	MI.17506	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	562	188	N	Y	Aac/Tac	-12,62	0	0	possibly_damaging	0,49	neutral	0,7	neutral	4,45	deleterious	-3,52	neutral	-1,44	low_impact	0,91	neutral	0,81	neutral	0,75	deleterious	0,76	9,2	0,21	0,45	neutral	0,45	disease	0,52	neutral	0,28	neutral	0,47	1	neutral	0,39	deleterious	0,61	neutral	-3	deleterious	0,58	medium_impact	-0,7	medium_impact	0,41	medium_impact	-0,23	0,1	0,8	29,41	21,06	N	0,25	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11322	11322	A	C	MI.17507	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	563	188	N	T	aAc/aCc	-9,39	0	0	benign	0	neutral	0,78	neutral	4,5	neutral	-1,68	neutral	-0,45	neutral_impact	0,58	neutral	0,81	neutral	1	neutral	-1,11	0,01	0,7	0,75	neutral	0,33	neutral	0,2	neutral	0,25	neutral	0,36	3	neutral	0,21	deleterious	0,89	neutral	-6	neutral	0,19	high_impact	2,1	medium_impact	0,51	medium_impact	-0,55	0,11	0,8	29,41	21,06	N	0,36	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11322	11322	A	T	MI.17508	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	563	188	N	I	aAc/aTc	-9,39	0	0	benign	0	neutral	0,43	neutral	4,51	neutral	-1,54	neutral	-1,56	neutral_impact	0,76	neutral	0,77	neutral	0,8	neutral	1,57	13,68	0,22	0,45	neutral	0,33	disease	0,59	neutral	0,41	neutral	0,46	1	neutral	0,57	deleterious	0,72	neutral	-6	deleterious	0,48	high_impact	2,1	medium_impact	0,13	medium_impact	-0,37	0,07	0,8	29,41	21,06	N	0,33	N	0,6	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11322	11322	A	G	MI.17509	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	563	188	N	S	aAc/aGc	-9,39	0	0	benign	0,01	neutral	0,9	neutral	4,61	neutral	-0,25	neutral	-0,34	neutral_impact	0,1	neutral	0,76	neutral	0,99	neutral	-1,21	0,01	0,79	0,8	neutral	0,31	neutral	0,19	neutral	0,29	neutral	0,35	3	neutral	0,08	deleterious	0,95	neutral	-6	neutral	0,13	medium_impact	1,16	medium_impact	0,74	low_impact	-1,03	0,09	0,8	29,41	21,06	N	0,35	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8510	8510	A	G	MI.1751	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	145	49	K	E	Aaa/Gaa	-20	0	0	probably_damaging	0,97	neutral	0,3	neutral	1,47	neutral	-0,91	neutral	-0,48	low_impact	1,28	neutral	0,93	neutral	0,59	deleterious	2,4	18,82	0,6294906	0,85	neutral	0,21	neutral	0,26	neutral	0,46	neutral	0,1	8	neutral	0,98	neutral	0,17	neutral	-2	deleterious	0,69	low_impact	-2,19	medium_impact	0,08	medium_impact	0	0,68	0,85	NA	NA	N	0,42	N	0,42	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11323	11323	C	G	MI.17510	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	564	188	N	K	aaC/aaG	-3,4	0	0	benign	0,11	neutral	0,95	neutral	4,55	neutral	-0,94	neutral	-1,16	neutral_impact	0,76	neutral	0,78	neutral	0,52	deleterious	0,63	8,36	0,77	0,8	neutral	0,44	neutral	0,49	neutral	0,48	disease	0,51	0	neutral	0,04	deleterious	0,92	neutral	-6	neutral	0,24	medium_impact	0,14	medium_impact	0,92	medium_impact	-0,37	0,35	0,8	29,41	21,06	N	0,19	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11323	11323	C	A	MI.17511	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	564	188	N	K	aaC/aaA	-3,4	0	0	benign	0,11	neutral	0,95	neutral	4,55	neutral	-0,94	neutral	-1,16	neutral_impact	0,76	neutral	0,78	neutral	0,52	neutral	1,03	10,85	0,77	0,8	neutral	0,44	neutral	0,49	neutral	0,48	disease	0,51	0	neutral	0,04	deleterious	0,92	neutral	-6	neutral	0,24	medium_impact	0,14	medium_impact	0,92	medium_impact	-0,37	0,35	0,8	29,41	21,06	N	0,19	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11324	11324	T	A	MI.17512	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	565	189	S	T	Tcc/Acc	-3,17	0	0	benign	0,01	neutral	0,37	neutral	4,55	neutral	-0,92	neutral	-0,29	neutral_impact	0,55	neutral	0,81	neutral	1	deleterious	2,11	16,9	0,49	0,55	disease	0,51	neutral	0,26	neutral	0,23	neutral	0,38	2	neutral	0,62	deleterious	0,68	neutral	-6	deleterious	0,68	medium_impact	1,16	medium_impact	0,07	medium_impact	-0,58	0,39	0,8	22,88	16,69	N	0,4	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11324	11324	T	C	MI.17513	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	565	189	S	P	Tcc/Ccc	-3,17	0	0	benign	0,04	neutral	0,13	neutral	4,47	deleterious	-3,05	neutral	-2,42	low_impact	1,02	neutral	0,75	neutral	0,73	deleterious	3,94	23,5	0,17	0,45	disease	0,83	disease	0,82	neutral	0,29	disease	0,62	2	neutral	0,86	deleterious	0,55	neutral	-6	deleterious	0,83	medium_impact	0,58	medium_impact	-0,26	medium_impact	-0,12	0,12	0,8	22,88	16,69	N	0,34	N	0,75	polymorphism	1	0,05	.	.	.	.	.	MNGIE fibroblasts	.	.	.	.	.	.	.	.	.
chrM	11324	11324	T	G	MI.17514	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	565	189	S	A	Tcc/Gcc	-3,17	0	0	benign	0,36	neutral	0,26	neutral	4,53	neutral	-1,24	neutral	-1,5	low_impact	1,07	neutral	0,7	neutral	0,77	deleterious	3,64	23,2	0,51	0,6	neutral	0,39	neutral	0,47	neutral	0,47	neutral	0,49	0	neutral	0,69	neutral	0,45	neutral	-6	deleterious	0,68	medium_impact	-0,48	medium_impact	-0,05	medium_impact	-0,07	0,18	0,8	22,88	16,69	N	0,4	N	0,27	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11325	11325	C	T	MI.17515	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	566	189	S	F	tCc/tTc	-3,42	0	0	possibly_damaging	0,9	neutral	0,15	neutral	4,49	neutral	-2,13	deleterious	-3,02	low_impact	0,97	neutral	0,7	neutral	0,58	deleterious	4,24	23,9	0,2	0,45	disease	0,64	disease	0,79	disease	0,54	disease	0,58	2	neutral	0,95	neutral	0,13	neutral	-3	deleterious	0,79	low_impact	-1,61	medium_impact	-0,22	medium_impact	-0,17	0,09	0,8	22,88	16,69	N	0,29	N	0,93	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11325	11325	C	G	MI.17516	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	566	189	S	C	tCc/tGc	-3,42	0	0	probably_damaging	0,95	deleterious	0,04	neutral	4,46	deleterious	-4,56	deleterious	-2,59	medium_impact	2,31	neutral	0,67	neutral	0,47	deleterious	3,56	23,1	0,15	0,4	disease	0,83	disease	0,78	disease	0,51	disease	0,72	4	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,79	low_impact	-1,92	medium_impact	-0,57	medium_impact	1,16	0,12	0,8	22,88	16,69	N	0,31	N	0,6	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11325	11325	C	A	MI.17517	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	566	189	S	Y	tCc/tAc	-3,42	0	0	probably_damaging	0,93	neutral	0,2	neutral	4,52	neutral	-1,45	deleterious	-2,98	low_impact	1,54	neutral	0,81	neutral	0,58	deleterious	4,07	23,7	0,16	0,45	disease	0,74	disease	0,79	disease	0,54	disease	0,68	4	neutral	0,96	neutral	0,14	neutral	-2	deleterious	0,8	low_impact	-1,77	medium_impact	-0,14	medium_impact	0,4	0,15	0,8	22,88	16,69	N	0,28	N	0,93	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11327	11327	T	G	MI.17518	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	568	190	W	G	Tga/Gga	-8,49	0	0	probably_damaging	1	neutral	0,08	neutral	4,64	neutral	-0,03	deleterious	-8,55	low_impact	0,85	neutral	0,74	neutral	0,48	deleterious	3,89	23,5	0,1	0,4	disease	0,58	disease	0,77	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	-0,39	medium_impact	-0,29	0,23	0,8	17,86	20,91	N	0,35	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11327	11327	T	C	MI.17519	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	568	190	W	R	Tga/Cga	-8,49	0	0	probably_damaging	1	neutral	0,07	neutral	4,63	neutral	-0,31	deleterious	-9,01	low_impact	1,5	neutral	0,72	neutral	0,28	deleterious	3,52	23,1	0,11	0,4	disease	0,57	disease	0,87	disease	0,73	disease	0,8	6	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,43	medium_impact	0,36	0,13	0,8	17,86	20,91	N	0,31	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8510	8510	A	C	MI.1752	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	145	49	K	Q	Aaa/Caa	-20	0	0	probably_damaging	0,99	neutral	0,31	neutral	1,41	neutral	-1,81	neutral	-0,51	neutral_impact	0,73	neutral	1	neutral	0,76	deleterious	1,96	15,99	0,6294906	0,85	neutral	0,27	neutral	0,21	neutral	0,32	neutral	0,11	8	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,67	low_impact	-2,65	medium_impact	0,1	medium_impact	-0,47	0,72	0,85	NA	NA	N	0,48	N	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11328	11328	G	T	MI.17520	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	569	190	W	L	tGa/tTa	1,87	0,02	0	probably_damaging	1	neutral	0,24	neutral	4,74	neutral	1,56	deleterious	-8,19	neutral_impact	0,28	neutral	0,79	neutral	0,68	deleterious	4,23	23,9	0,13	0,4	neutral	0,37	disease	0,77	disease	0,63	disease	0,56	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	-0,08	medium_impact	-0,85	0,2	0,8	17,86	20,91	N	0,33	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11328	11328	G	C	MI.17521	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	569	190	W	S	tGa/tCa	1,87	0,02	0	probably_damaging	1	neutral	0,18	neutral	4,71	neutral	1,15	deleterious	-8,9	neutral_impact	-0,11	neutral	0,81	neutral	0,63	deleterious	3,92	23,5	0,11	0,4	neutral	0,24	disease	0,8	disease	0,6	disease	0,55	1	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	-0,17	low_impact	-1,24	0,17	0,8	17,86	20,91	N	0,34	N	0,95	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11329	11329	A	C	MI.17522	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	570	190	W	C	tgA/tgC	0,26	0	0,01	probably_damaging	1	deleterious	0,04	neutral	4,6	neutral	-1,87	deleterious	-8,42	medium_impact	2,05	neutral	0,74	neutral	0,34	deleterious	3,99	23,6	0,12	0,4	disease	0,63	disease	0,88	disease	0,59	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-3,54	medium_impact	-0,57	medium_impact	0,9	0,18	0,8	17,86	20,91	N	0,35	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11329	11329	A	T	MI.17523	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	570	190	W	C	tgA/tgT	0,26	0	0,01	probably_damaging	1	deleterious	0,04	neutral	4,6	neutral	-1,87	deleterious	-8,42	medium_impact	2,05	neutral	0,74	neutral	0,34	deleterious	4,09	23,7	0,12	0,4	disease	0,63	disease	0,88	disease	0,59	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-3,54	medium_impact	-0,57	medium_impact	0,9	0,18	0,8	17,86	20,91	N	0,35	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11330	11330	G	T	MI.17524	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	571	191	A	S	Gcc/Tcc	0,49	0	0	benign	0,02	neutral	0,63	neutral	4,6	neutral	-2,17	neutral	1,35	neutral_impact	-1,08	neutral	0,77	neutral	0,91	neutral	-0,95	0,02	0,28	0,45	neutral	0,35	neutral	0,14	neutral	0,14	neutral	0,24	5	neutral	0,34	deleterious	0,81	neutral	-6	neutral	0,14	medium_impact	0,87	medium_impact	0,33	low_impact	-2,19	0,42	0,8	20,7	16,32	N	0,36	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11330	11330	G	C	MI.17525	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	571	191	A	P	Gcc/Ccc	0,49	0	0	possibly_damaging	0,65	neutral	0,25	neutral	4,55	deleterious	-3,05	neutral	-1,62	neutral_impact	0,35	neutral	0,76	neutral	0,67	deleterious	2,12	16,97	0,07	0,35	disease	0,65	disease	0,8	neutral	0,41	disease	0,59	2	neutral	0,78	neutral	0,3	neutral	-3	deleterious	0,56	medium_impact	-0,97	medium_impact	-0,07	medium_impact	-0,78	0,51	0,8	20,7	16,32	N	0,31	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11330	11330	G	A	MI.17526	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	571	191	A	T	Gcc/Acc	0,49	0	0	benign	0,03	neutral	0,58	neutral	4,61	neutral	-1,99	neutral	0,05	neutral_impact	-0,46	neutral	0,75	neutral	0,95	neutral	0,91	10,11	0,25	0,45	neutral	0,3	neutral	0,21	neutral	0,14	neutral	0,37	3	neutral	0,38	deleterious	0,78	neutral	-6	neutral	0,21	medium_impact	0,7	medium_impact	0,28	low_impact	-1,58	0,76	0,85	20,7	16,32	N	0,43	N	0,27	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11331	11331	C	T	MI.17527	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	572	191	A	V	gCc/gTc	-0,2	0	0	benign	0,25	neutral	0,59	neutral	4,58	neutral	-1,1	neutral	-2,06	neutral_impact	0,11	neutral	0,8	neutral	0,69	deleterious	2,59	20,1	0,21	0,45	neutral	0,22	neutral	0,43	neutral	0,39	neutral	0,47	1	neutral	0,3	deleterious	0,67	neutral	-6	neutral	0,3	medium_impact	-0,27	medium_impact	0,29	low_impact	-1,02	0,78	0,85	20,7	16,32	N	0,24	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11331	11331	C	A	MI.17528	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	572	191	A	D	gCc/gAc	-0,2	0	0	benign	0,36	neutral	0,32	neutral	4,56	deleterious	-3,13	neutral	-1,12	neutral_impact	0,47	neutral	0,76	neutral	0,44	deleterious	2,8	21,4	0,04	0,35	disease	0,68	disease	0,76	disease	0,56	disease	0,75	5	neutral	0,62	deleterious	0,48	neutral	-6	deleterious	0,44	medium_impact	-0,48	medium_impact	0,02	medium_impact	-0,66	0,23	0,8	20,7	16,32	N	0,29	N	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11331	11331	C	G	MI.17529	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	572	191	A	G	gCc/gGc	-0,2	0	0	benign	0,25	neutral	0,47	neutral	4,62	neutral	-2,72	neutral	-0,35	neutral_impact	0,16	neutral	0,78	neutral	0,72	deleterious	0,44	6,92	0,3	0,45	disease	0,51	neutral	0,29	neutral	0,36	neutral	0,27	5	neutral	0,43	deleterious	0,61	neutral	-6	neutral	0,24	medium_impact	-0,27	medium_impact	0,17	medium_impact	-0,97	0,56	0,8	20,7	16,32	N	0,33	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8511	8511	A	T	MI.1753	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	146	49	K	M	aAa/aTa	0,59	0	0	probably_damaging	1	neutral	0,23	neutral	1,34	deleterious	-4,91	neutral	-1,34	neutral_impact	0,48	neutral	0,98	neutral	0,89	deleterious	2,93	22	0,5726291	0,85	disease	0,56	neutral	0,11	neutral	0,47	neutral	0,05	9	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	-0,01	medium_impact	-0,69	0,59	0,85	NA	NA	P	0,6	P	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11333	11333	A	G	MI.17530	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	574	192	N	D	Aac/Gac	-13,55	0	0	benign	0,03	neutral	0,71	neutral	4,6	neutral	-1,44	neutral	-1,68	low_impact	1,51	neutral	0,71	neutral	0,75	neutral	1,76	14,78	0,49	0,55	neutral	0,43	neutral	0,3	neutral	0,34	neutral	0,45	1	neutral	0,24	deleterious	0,84	neutral	-6	deleterious	0,7	medium_impact	0,7	medium_impact	0,42	medium_impact	0,37	0,3	0,8	22,88	24,94	N	0,36	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11333	11333	A	T	MI.17531	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	574	192	N	Y	Aac/Tac	-13,55	0	0	possibly_damaging	0,61	neutral	0,3	neutral	4,61	neutral	-1,17	deleterious	-4	low_impact	1,3	neutral	0,81	neutral	0,56	deleterious	3,7	23,3	0,14	0,4	disease	0,7	disease	0,74	neutral	0,37	disease	0,59	2	neutral	0,72	neutral	0,35	neutral	-3	deleterious	0,79	medium_impact	-0,9	medium_impact	0	medium_impact	0,16	0,26	0,8	22,88	24,94	N	0,31	N	0,81	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11333	11333	A	C	MI.17532	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	574	192	N	H	Aac/Cac	-13,55	0	0	benign	0,01	neutral	0,28	neutral	4,6	neutral	-1,69	neutral	-1,86	low_impact	1,08	neutral	0,69	neutral	0,8	neutral	1,49	13,25	0,35	0,5	disease	0,56	disease	0,52	neutral	0,39	disease	0,51	0	neutral	0,71	deleterious	0,64	neutral	-6	deleterious	0,72	medium_impact	1,16	medium_impact	-0,03	medium_impact	-0,06	0,18	0,8	22,88	24,94	N	0,42	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11334	11334	A	C	MI.17533	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	575	192	N	T	aAc/aCc	-0,66	0	0	possibly_damaging	0,64	neutral	0,27	neutral	4,67	neutral	0,4	deleterious	-2,82	low_impact	1,89	neutral	0,77	neutral	0,96	deleterious	2,3	18,16	0,26	0,45	neutral	0,35	disease	0,6	neutral	0,28	neutral	0,48	1	neutral	0,76	neutral	0,32	neutral	-3	deleterious	0,7	medium_impact	-0,95	medium_impact	-0,04	medium_impact	0,74	0,28	0,8	22,88	24,94	N	0,41	N	0,32	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11334	11334	A	T	MI.17534	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	575	192	N	I	aAc/aTc	-0,66	0	0	possibly_damaging	0,87	neutral	0,17	neutral	4,78	neutral	1,64	deleterious	-4,86	low_impact	1,89	neutral	0,82	neutral	0,52	deleterious	4,02	23,6	0,17	0,45	neutral	0,4	disease	0,84	neutral	0,43	disease	0,71	4	neutral	0,93	neutral	0,15	neutral	-3	deleterious	0,76	low_impact	-1,49	medium_impact	-0,18	medium_impact	0,74	0,18	0,8	22,88	24,94	N	0,35	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11334	11334	A	G	MI.17535	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	575	192	N	S	aAc/aGc	-0,66	0	0	benign	0,36	neutral	0,62	neutral	4,67	neutral	0,44	neutral	-1,95	neutral_impact	0,21	neutral	0,72	neutral	0,97	neutral	1,64	14,08	0,52	0,6	neutral	0,2	neutral	0,36	neutral	0,27	neutral	0,45	1	neutral	0,32	deleterious	0,63	neutral	-6	deleterious	0,66	medium_impact	-0,48	medium_impact	0,32	medium_impact	-0,92	0,18	0,8	22,88	24,94	N	0,37	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11335	11335	C	G	MI.17536	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	576	192	N	K	aaC/aaG	0,03	0	0	possibly_damaging	0,56	neutral	0,08	neutral	4,62	neutral	-0,47	deleterious	-2,96	low_impact	1,38	neutral	0,79	neutral	0,37	deleterious	3,9	23,5	0,43	0,55	neutral	0,35	disease	0,73	disease	0,56	disease	0,71	4	neutral	0,92	neutral	0,26	neutral	-3	deleterious	0,73	medium_impact	-0,82	medium_impact	-0,39	medium_impact	0,24	0,31	0,8	22,88	24,94	N	0,31	N	0,71	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11335	11335	C	A	MI.17537	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	576	192	N	K	aaC/aaA	0,03	0	0	possibly_damaging	0,56	neutral	0,08	neutral	4,62	neutral	-0,47	deleterious	-2,96	low_impact	1,38	neutral	0,79	neutral	0,37	deleterious	4,38	24,1	0,43	0,55	neutral	0,35	disease	0,73	disease	0,56	disease	0,71	4	neutral	0,92	neutral	0,26	neutral	-3	deleterious	0,73	medium_impact	-0,82	medium_impact	-0,39	medium_impact	0,24	0,31	0,8	22,88	24,94	N	0,31	N	0,71	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11336	11336	A	T	MI.17538	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	577	193	N	Y	Aac/Tac	-4,58	0	0	benign	0,03	neutral	1	neutral	4,57	neutral	-1,86	neutral	-2,28	low_impact	0,87	neutral	0,77	neutral	0,71	deleterious	2,18	17,41	0,14	0,4	neutral	0,48	disease	0,56	neutral	0,42	neutral	0,47	1	neutral	0,03	deleterious	0,99	neutral	-6	deleterious	0,61	medium_impact	0,7	high_impact	1,88	medium_impact	-0,27	0,27	0,8	21,35	22,84	N	0,19	N	0,71	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11336	11336	A	C	MI.17539	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	577	193	N	H	Aac/Cac	-4,58	0	0	possibly_damaging	0,75	neutral	0,54	neutral	4,56	neutral	-2,37	neutral	-1,17	low_impact	1,3	neutral	0,85	neutral	0,89	neutral	1,62	13,97	0,35	0,5	neutral	0,23	neutral	0,41	neutral	0,39	neutral	0,44	1	neutral	0,72	neutral	0,4	neutral	-3	deleterious	0,55	low_impact	-1,17	medium_impact	0,24	medium_impact	0,16	0,19	0,8	21,35	22,84	N	0,29	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8511	8511	A	C	MI.1754	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	146	49	K	T	aAa/aCa	0,59	0	0	probably_damaging	0,98	neutral	0,44	neutral	1,42	neutral	-1,62	neutral	1,28	neutral_impact	-1,47	neutral	0,99	neutral	0,97	neutral	0,95	10,39	0,49162191	0,85	neutral	0,15	neutral	0,23	neutral	0,33	neutral	0,14	7	deleterious	0,98	neutral	0,23	neutral	-2	deleterious	0,66	low_impact	-2,36	medium_impact	0,23	low_impact	-2,36	0,71	0,85	NA	NA	N	0,43	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11336	11336	A	G	MI.17540	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	577	193	N	D	Aac/Gac	-4,58	0	0	benign	0,02	neutral	0,21	neutral	4,56	neutral	-2,12	neutral	-0,93	low_impact	1,45	neutral	0,8	neutral	0,86	deleterious	0,66	8,6	0,52	0,6	neutral	0,42	neutral	0,45	disease	0,51	neutral	0,48	1	neutral	0,78	deleterious	0,6	neutral	-6	neutral	0,3	medium_impact	0,87	medium_impact	-0,12	medium_impact	0,31	0,32	0,8	21,35	22,84	N	0,4	N	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11337	11337	A	G	MI.17541	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	578	193	N	S	aAc/aGc	-2,5	0	0	benign	0,03	neutral	0,42	neutral	4,66	neutral	0,17	neutral	-0,57	neutral_impact	0,11	neutral	0,78	neutral	0,99	neutral	-0,47	0,27	0,47	0,55	neutral	0,24	neutral	0,26	neutral	0,26	neutral	0,43	1	neutral	0,56	deleterious	0,7	neutral	-6	neutral	0,1	medium_impact	0,7	medium_impact	0,12	low_impact	-1,02	0,27	0,8	21,35	22,84	N	0,39	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11337	11337	A	T	MI.17542	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	578	193	N	I	aAc/aTc	-2,5	0	0	possibly_damaging	0,68	neutral	0,42	neutral	4,64	neutral	-0,07	deleterious	-2,56	neutral_impact	-0,09	neutral	0,81	neutral	0,99	deleterious	2,45	19,15	0,16	0,45	neutral	0,32	disease	0,64	neutral	0,28	neutral	0,44	1	neutral	0,69	neutral	0,37	neutral	-3	deleterious	0,54	low_impact	-1,03	medium_impact	0,12	low_impact	-1,22	0,19	0,8	21,35	22,84	N	0,28	N	0,12	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11337	11337	A	C	MI.17543	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	578	193	N	T	aAc/aCc	-2,5	0	0	benign	0,25	neutral	0,4	neutral	4,69	neutral	0,59	neutral	-1,24	low_impact	0,96	neutral	0,76	neutral	0,99	deleterious	0,27	5,37	0,27	0,45	neutral	0,31	neutral	0,32	neutral	0,23	neutral	0,45	1	neutral	0,52	deleterious	0,58	neutral	-6	neutral	0,21	medium_impact	-0,27	medium_impact	0,1	medium_impact	-0,18	0,26	0,8	21,35	22,84	N	0,4	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11338	11338	C	A	MI.17544	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	579	193	N	K	aaC/aaA	-2,04	0	0	benign	0,36	neutral	0,36	neutral	4,59	neutral	-1,16	neutral	-0,4	neutral_impact	0,1	neutral	0,73	neutral	0,75	neutral	-0,13	1,49	0,37	0,5	neutral	0,27	neutral	0,16	neutral	0,33	neutral	0,23	5	neutral	0,57	deleterious	0,5	neutral	-6	neutral	0,27	medium_impact	-0,48	medium_impact	0,06	low_impact	-1,03	0,37	0,8	21,35	22,84	N	0,43	N	0,61	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11338	11338	C	G	MI.17545	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	579	193	N	K	aaC/aaG	-2,04	0	0	benign	0,36	neutral	0,36	neutral	4,59	neutral	-1,16	neutral	-0,4	neutral_impact	0,1	neutral	0,73	neutral	0,75	neutral	-0,57	0,15	0,37	0,5	neutral	0,27	neutral	0,16	neutral	0,33	neutral	0,23	5	neutral	0,57	deleterious	0,5	neutral	-6	neutral	0,27	medium_impact	-0,48	medium_impact	0,06	low_impact	-1,03	0,37	0,8	21,35	22,84	N	0,43	N	0,61	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11339	11339	T	G	MI.17546	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	580	194	L	V	Tta/Gta	-11,02	0	0,01	benign	0,26	neutral	0,16	neutral	4,45	neutral	-1,52	neutral	-0,85	low_impact	1,68	neutral	0,76	neutral	0,83	neutral	1,43	12,95	0,29	0,45	neutral	0,37	disease	0,5	neutral	0,47	neutral	0,48	0	neutral	0,81	neutral	0,45	neutral	-6	neutral	0,25	medium_impact	-0,29	medium_impact	-0,2	medium_impact	0,54	0,64	0,8	27,67	21,8	N	0,44	N	0,22	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11339	11339	T	A	MI.17547	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	580	194	L	M	Tta/Ata	-11,02	0	0,01	probably_damaging	0,9	neutral	0,22	neutral	4,4	deleterious	-3,16	neutral	-0,66	low_impact	1,62	neutral	0,75	neutral	0,97	deleterious	2,29	18,1	0,28	0,45	neutral	0,41	neutral	0,31	neutral	0,27	neutral	0,47	1	neutral	0,94	neutral	0,16	neutral	-2	deleterious	0,59	low_impact	-1,61	medium_impact	-0,11	medium_impact	0,48	0,51	0,8	27,67	21,8	N	0,49	N	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11340	11340	T	G	MI.17548	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	581	194	L	W	tTa/tGa	-6,65	0	0	probably_damaging	0,98	neutral	0,13	neutral	4,34	deleterious	-4,03	deleterious	-3,28	low_impact	1,53	neutral	0,73	neutral	0,43	deleterious	3,62	23,2	0,04	0,35	neutral	0,22	disease	0,79	disease	0,62	disease	0,75	5	deleterious	0,99	neutral	0,08	neutral	-2	deleterious	0,67	low_impact	-2,31	medium_impact	-0,26	medium_impact	0,39	0,29	0,8	27,67	21,8	N	0,3	N	0,47	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11340	11340	T	C	MI.17549	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	581	194	L	S	tTa/tCa	-6,65	0	0	probably_damaging	0,95	deleterious	0,04	neutral	4,36	deleterious	-3,91	deleterious	-3,37	medium_impact	2,07	neutral	0,73	neutral	0,72	deleterious	3,56	23,1	0,02	0,35	disease	0,51	disease	0,74	disease	0,59	disease	0,72	4	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,7	low_impact	-1,92	medium_impact	-0,57	medium_impact	0,92	0,27	0,8	27,67	21,8	N	0,33	N	0,58	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8512	8512	A	C	MI.1755	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	147	49	K	N	aaA/aaC	-2,88	0	0,03	probably_damaging	0,99	neutral	0,34	neutral	1,47	neutral	-0,92	neutral	1,74	neutral_impact	-0,68	neutral	1	neutral	0,95	deleterious	2,23	17,7	0,82750062	0,9	neutral	0,15	neutral	0,07	neutral	0,32	neutral	0,04	9	deleterious	0,99	neutral	0,18	neutral	-2	deleterious	0,64	low_impact	-2,65	medium_impact	0,13	low_impact	-1,68	0,8	0,85	NA	NA	N	0,47	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11341	11341	A	T	MI.17550	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	582	194	L	F	ttA/ttT	5,55	0,85	0	benign	0,11	neutral	0,45	neutral	4,5	neutral	-2,79	neutral	-1,2	neutral_impact	0,62	neutral	0,79	neutral	0,99	neutral	1,62	13,96	0,2	0,45	neutral	0,43	neutral	0,48	neutral	0,31	neutral	0,47	1	neutral	0,48	deleterious	0,67	neutral	-6	deleterious	0,59	medium_impact	0,14	medium_impact	0,15	medium_impact	-0,51	0,55	0,8	27,67	21,8	N	0,48	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11341	11341	A	C	MI.17551	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	582	194	L	F	ttA/ttC	5,55	0,85	0	benign	0,11	neutral	0,45	neutral	4,5	neutral	-2,79	neutral	-1,2	neutral_impact	0,62	neutral	0,79	neutral	0,99	neutral	1,48	13,19	0,2	0,45	neutral	0,43	neutral	0,48	neutral	0,31	neutral	0,47	1	neutral	0,48	deleterious	0,67	neutral	-6	deleterious	0,59	medium_impact	0,14	medium_impact	0,15	medium_impact	-0,51	0,55	0,8	27,67	21,8	N	0,48	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11342	11342	A	T	MI.17552	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	583	195	M	L	Ata/Tta	-9,87	0	0	benign	0	neutral	1	neutral	4,84	neutral	2,07	neutral	0,12	neutral_impact	-1,24	neutral	0,77	neutral	0,97	neutral	1,05	10,96	0,25	0,45	neutral	0,21	neutral	0,46	neutral	0,29	neutral	0,44	1	neutral	0	deleterious	1	neutral	-6	deleterious	0,5	high_impact	2,1	high_impact	1,88	low_impact	-2,35	0,27	0,8	20,04	21,95	N	0,32	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11342	11342	A	C	MI.17553	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	583	195	M	L	Ata/Cta	-9,87	0	0	benign	0	neutral	1	neutral	4,84	neutral	2,07	neutral	0,12	neutral_impact	-1,24	neutral	0,77	neutral	0,97	neutral	0,99	10,59	0,25	0,45	neutral	0,21	neutral	0,46	neutral	0,29	neutral	0,44	1	neutral	0	deleterious	1	neutral	-6	deleterious	0,5	high_impact	2,1	high_impact	1,88	low_impact	-2,35	0,27	0,8	20,04	21,95	N	0,32	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11342	11342	A	G	MI.17554	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	583	195	M	V	Ata/Gta	-9,87	0	0	benign	0	neutral	0,23	neutral	4,69	neutral	1,36	neutral	-1,34	neutral_impact	0,62	neutral	0,76	neutral	0,73	deleterious	2,6	20,2	0,24	0,45	neutral	0,45	disease	0,7	disease	0,64	disease	0,74	5	neutral	0,77	deleterious	0,62	neutral	-6	deleterious	0,62	high_impact	2,1	medium_impact	-0,09	medium_impact	-0,51	0,31	0,8	20,04	21,95	N	0,33	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11343	11343	T	A	MI.17555	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	584	195	M	K	aTa/aAa	-2,96	0	0	benign	0,23	neutral	0,07	neutral	4,59	neutral	-2,31	deleterious	-2,82	low_impact	1,84	neutral	0,64	neutral	0,45	deleterious	4,06	23,7	0,03	0,35	disease	0,77	disease	0,87	disease	0,71	disease	0,82	6	neutral	0,92	neutral	0,42	neutral	-6	deleterious	0,81	medium_impact	-0,23	medium_impact	-0,43	medium_impact	0,69	0,26	0,8	20,04	21,95	N	0,3	N	0,88	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11343	11343	T	C	MI.17556	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	584	195	M	T	aTa/aCa	-2,96	0	0	benign	0	neutral	0,07	neutral	4,62	neutral	-0,18	neutral	-2,11	low_impact	1,22	neutral	0,78	neutral	0,95	neutral	1,78	14,9	0,09	0,35	disease	0,6	disease	0,74	disease	0,64	disease	0,63	3	neutral	0,93	deleterious	0,54	neutral	-6	deleterious	0,76	high_impact	2,1	medium_impact	-0,43	medium_impact	0,08	0,15	0,8	20,04	21,95	N	0,31	N	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11344	11344	A	T	MI.17557	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	585	195	M	I	atA/atT	2,56	0,91	0	benign	0	neutral	0,27	neutral	4,73	neutral	1,34	neutral	-0,96	neutral_impact	0,62	neutral	0,74	neutral	0,68	deleterious	3,34	22,9	0,25	0,45	neutral	0,34	disease	0,81	neutral	0,42	disease	0,56	1	neutral	0,73	deleterious	0,64	neutral	-6	deleterious	0,7	high_impact	2,1	medium_impact	-0,04	medium_impact	-0,51	0,37	0,8	20,04	21,95	N	0,34	N	0,42	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11344	11344	A	C	MI.17558	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	585	195	M	I	atA/atC	2,56	0,91	0	benign	0	neutral	0,27	neutral	4,73	neutral	1,34	neutral	-0,96	neutral_impact	0,62	neutral	0,74	neutral	0,68	deleterious	3,33	22,9	0,25	0,45	neutral	0,34	disease	0,81	neutral	0,42	disease	0,56	1	neutral	0,73	deleterious	0,64	neutral	-6	deleterious	0,7	high_impact	2,1	medium_impact	-0,04	medium_impact	-0,51	0,37	0,8	20,04	21,95	N	0,34	N	0,42	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11345	11345	T	G	MI.17559	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	586	196	W	G	Tga/Gga	0,26	0,9	0	benign	0,08	neutral	0,16	neutral	4,65	neutral	0,06	deleterious	-10,01	medium_impact	2,48	neutral	0,74	neutral	0,58	deleterious	3,82	23,4	0,07	0,35	neutral	0,34	disease	0,9	disease	0,77	disease	0,65	3	neutral	0,82	deleterious	0,54	neutral	-3	deleterious	0,77	medium_impact	0,28	medium_impact	-0,2	medium_impact	1,33	0,21	0,8	46,19	9,46	N	0,43	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8512	8512	A	T	MI.1756	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	147	49	K	N	aaA/aaT	-2,88	0	0,03	probably_damaging	0,99	neutral	0,34	neutral	1,47	neutral	-0,92	neutral	1,74	neutral_impact	-0,68	neutral	1	neutral	0,95	deleterious	2,32	18,28	0,82750062	0,9	neutral	0,15	neutral	0,07	neutral	0,32	neutral	0,04	9	deleterious	0,99	neutral	0,18	neutral	-2	deleterious	0,64	low_impact	-2,65	medium_impact	0,13	low_impact	-1,68	0,8	0,85	NA	NA	N	0,47	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11345	11345	T	C	MI.17560	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	586	196	W	R	Tga/Cga	0,26	0,9	0	probably_damaging	0,97	deleterious	0,02	neutral	4,6	neutral	-2,63	deleterious	-10,79	high_impact	3,92	neutral	0,69	neutral	0,36	deleterious	3,51	23,1	0,04	0,35	disease	0,57	disease	0,95	disease	0,82	disease	0,92	8	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,86	low_impact	-2,14	medium_impact	-0,75	high_impact	2,75	0,24	0,8	46,19	9,46	N	0,49	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11346	11346	G	C	MI.17561	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	587	196	W	S	tGa/tCa	3,02	1	0	possibly_damaging	0,89	neutral	0,07	neutral	4,75	neutral	-1,12	deleterious	-10,79	medium_impact	2,6	neutral	0,75	neutral	0,57	deleterious	3,94	23,5	0,07	0,35	neutral	0,38	disease	0,92	disease	0,75	disease	0,62	2	neutral	0,97	neutral	0,09	NA	0	deleterious	0,8	low_impact	-1,57	medium_impact	-0,43	medium_impact	1,45	0,2	0,8	46,19	9,46	N	0,52	P	0,93	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11346	11346	G	T	MI.17562	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	587	196	W	L	tGa/tTa	3,02	1	0	probably_damaging	0,93	neutral	0,24	neutral	4,74	neutral	1,04	deleterious	-10,02	medium_impact	2,04	neutral	0,78	neutral	0,47	deleterious	4,18	23,8	0,09	0,4	neutral	0,27	disease	0,91	disease	0,75	disease	0,77	5	neutral	0,95	neutral	0,16	deleterious	1	deleterious	0,74	low_impact	-1,77	medium_impact	-0,08	medium_impact	0,89	0,13	0,8	46,19	9,46	N	0,45	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11347	11347	A	T	MI.17563	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	588	196	W	C	tgA/tgT	4,17	1	0	probably_damaging	0,98	deleterious	0,02	neutral	4,59	neutral	-0,8	deleterious	-10,02	medium_impact	2,88	neutral	0,74	neutral	0,39	deleterious	4,07	23,7	0,07	0,35	disease	0,63	disease	0,95	disease	0,76	disease	0,9	8	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,83	low_impact	-2,31	medium_impact	-0,75	medium_impact	1,72	0,17	0,8	46,19	9,46	N	0,51	P	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11347	11347	A	C	MI.17564	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	588	196	W	C	tgA/tgC	4,17	1	0	probably_damaging	0,98	deleterious	0,02	neutral	4,59	neutral	-0,8	deleterious	-10,02	medium_impact	2,88	neutral	0,74	neutral	0,39	deleterious	3,93	23,5	0,07	0,35	disease	0,63	disease	0,95	disease	0,76	disease	0,9	8	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,83	low_impact	-2,31	medium_impact	-0,75	medium_impact	1,72	0,17	0,8	46,19	9,46	N	0,5	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11348	11348	C	G	MI.17565	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	589	197	L	V	Cta/Gta	0,03	0	0	possibly_damaging	0,9	neutral	0,3	neutral	4,39	neutral	-1,92	neutral	-1,35	medium_impact	2,19	neutral	0,73	neutral	0,4	deleterious	2,01	16,24	0,3	0,45	neutral	0,34	disease	0,55	neutral	0,34	neutral	0,47	1	neutral	0,91	neutral	0,2	NA	0	deleterious	0,7	low_impact	-1,61	medium_impact	0	medium_impact	1,04	0,62	0,8	20,26	19,44	N	0,39	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11348	11348	C	A	MI.17566	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	589	197	L	M	Cta/Ata	0,03	0	0	possibly_damaging	0,76	neutral	0,1	neutral	4,3	deleterious	-3,69	neutral	-0,99	medium_impact	2,29	neutral	0,75	neutral	0,33	deleterious	2,47	19,26	0,24	0,45	neutral	0,19	disease	0,54	neutral	0,37	neutral	0,45	1	neutral	0,93	neutral	0,17	NA	0	deleterious	0,68	low_impact	-1,19	medium_impact	-0,33	medium_impact	1,14	0,48	0,8	20,26	19,44	N	0,44	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11349	11349	T	G	MI.17567	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	590	197	L	R	cTa/cGa	-2,73	0	0	probably_damaging	0,98	deleterious	0,01	neutral	4,27	deleterious	-4,93	deleterious	-3,29	high_impact	4,05	neutral	0,68	damaging	0,09	deleterious	4,17	23,8	0,02	0,35	disease	0,71	disease	0,94	disease	0,71	disease	0,85	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,89	low_impact	-2,31	medium_impact	-0,92	high_impact	2,88	0,23	0,8	20,26	19,44	N	0,29	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11349	11349	T	A	MI.17568	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	590	197	L	Q	cTa/cAa	-2,73	0	0	probably_damaging	0,99	deleterious	0,01	neutral	4,27	deleterious	-5,62	deleterious	-3,24	high_impact	4,05	neutral	0,69	damaging	0,1	deleterious	4,31	24	0,03	0,35	disease	0,73	disease	0,85	disease	0,58	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,59	medium_impact	-0,92	high_impact	2,88	0,42	0,8	20,26	19,44	N	0,33	N	0,96	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11349	11349	T	C	MI.17569	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	590	197	L	P	cTa/cCa	-2,73	0	0	probably_damaging	1	deleterious	0,01	neutral	4,26	deleterious	-5,77	deleterious	-3,84	medium_impact	3,36	neutral	0,63	damaging	0,08	deleterious	3,87	23,5	0,02	0,35	disease	0,78	disease	0,93	disease	0,7	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,89	low_impact	-3,54	medium_impact	-0,92	high_impact	2,2	0,37	0,8	20,26	19,44	N	0,25	N	0,94	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8513	8513	C	A	MI.1757	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	148	50	P	T	Ccc/Acc	-4,27	0	0	probably_damaging	1	neutral	0,41	neutral	1,68	deleterious	-7,01	deleterious	-5,77	neutral_impact	0,54	neutral	0,95	neutral	0,59	deleterious	3,85	23,4	0,50472207	0,85	disease	0,62	neutral	0,34	disease	0,53	neutral	0,23	5	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	0,2	medium_impact	-0,64	0,65	0,85	1,47	8,21	N	0,39	N	0,73	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11351	11351	G	T	MI.17570	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	592	198	A	S	Gct/Tct	-2,27	0	0	possibly_damaging	0,74	neutral	0,56	neutral	4,61	neutral	-2,51	neutral	-1,62	low_impact	1,64	neutral	0,72	neutral	0,63	deleterious	2,56	19,86	0,21	0,45	neutral	0,37	disease	0,75	neutral	0,33	disease	0,53	1	neutral	0,71	neutral	0,41	neutral	-3	deleterious	0,76	low_impact	-1,14	medium_impact	0,26	medium_impact	0,5	0,42	0,8	18,95	16,41	N	0,32	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11351	11351	G	A	MI.17571	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	592	198	A	T	Gct/Act	-2,27	0	0	benign	0,26	neutral	0,39	neutral	4,59	neutral	-2,3	deleterious	-2,51	medium_impact	2,58	neutral	0,78	neutral	0,73	deleterious	4,08	23,7	0,14	0,4	neutral	0,42	disease	0,86	neutral	0,46	disease	0,67	3	neutral	0,53	deleterious	0,57	neutral	-3	deleterious	0,8	medium_impact	-0,29	medium_impact	0,09	medium_impact	1,43	0,59	0,8	18,95	16,41	N	0,32	N	0,82	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11351	11351	G	C	MI.17572	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	592	198	A	P	Gct/Cct	-2,27	0	0	probably_damaging	0,97	neutral	0,2	neutral	4,55	deleterious	-4,38	deleterious	-3,27	medium_impact	2,92	neutral	0,66	neutral	0,32	deleterious	3,74	23,3	0,03	0,35	disease	0,65	disease	0,95	disease	0,67	disease	0,82	6	neutral	0,98	neutral	0,12	deleterious	1	deleterious	0,88	low_impact	-2,14	medium_impact	-0,14	medium_impact	1,76	0,49	0,8	18,95	16,41	N	0,29	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11352	11352	C	T	MI.17573	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	593	198	A	V	gCt/gTt	3,02	0,99	0	possibly_damaging	0,83	neutral	0,57	neutral	4,68	neutral	-1,04	deleterious	-2,84	medium_impact	2,18	neutral	0,76	neutral	0,49	deleterious	4,35	24,1	0,14	0,4	neutral	0,41	disease	0,87	disease	0,54	disease	0,68	4	neutral	0,81	neutral	0,37	NA	0	deleterious	0,78	low_impact	-1,37	medium_impact	0,27	medium_impact	1,03	0,64	0,8	18,95	16,41	N	0,44	N	0,72	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11352	11352	C	A	MI.17574	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	593	198	A	D	gCt/gAt	3,02	0,99	0	probably_damaging	0,94	neutral	0,2	neutral	4,54	deleterious	-5,38	deleterious	-3,69	high_impact	3,73	neutral	0,69	neutral	0,36	deleterious	4,52	24,3	0,03	0,35	neutral	0,44	disease	0,95	disease	0,66	disease	0,83	7	neutral	0,96	neutral	0,13	deleterious	2	deleterious	0,82	low_impact	-1,84	medium_impact	-0,14	high_impact	2,56	0,28	0,8	18,95	16,41	N	0,55	P	0,98	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11352	11352	C	G	MI.17575	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	593	198	A	G	gCt/gGt	3,02	0,99	0	benign	0,12	neutral	0,6	neutral	4,63	neutral	-1,15	neutral	-1,61	low_impact	1,23	neutral	0,7	neutral	0,62	deleterious	2,24	17,77	0,22	0,45	neutral	0,48	disease	0,51	neutral	0,3	neutral	0,45	1	neutral	0,3	deleterious	0,74	neutral	-6	deleterious	0,75	medium_impact	0,1	medium_impact	0,3	medium_impact	0,09	0,56	0,8	18,95	16,41	N	0,41	N	0,79	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11354	11354	T	A	MI.17576	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	595	199	Y	N	Tac/Aac	-5,96	0	0	possibly_damaging	0,8	deleterious	0,03	neutral	4,63	neutral	-0,82	neutral	-1,04	neutral_impact	0,14	neutral	0,71	neutral	0,64	deleterious	3,78	23,4	0,09	0,35	neutral	0,38	disease	0,85	neutral	0,48	disease	0,76	5	deleterious	0,98	neutral	0,12	deleterious	1	deleterious	0,7	low_impact	-1,28	medium_impact	-0,64	medium_impact	-0,99	0,18	0,8	14,81	11,39	N	0,35	N	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11354	11354	T	C	MI.17577	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	595	199	Y	H	Tac/Cac	-5,96	0	0	possibly_damaging	0,84	neutral	0,05	neutral	4,63	neutral	-1,06	neutral	-0,92	neutral_impact	0,7	neutral	0,75	neutral	0,53	deleterious	3,39	23	0,18	0,45	neutral	0,4	disease	0,69	disease	0,58	disease	0,68	4	neutral	0,97	neutral	0,11	neutral	-3	deleterious	0,67	low_impact	-1,39	medium_impact	-0,52	medium_impact	-0,43	0,21	0,8	14,81	11,39	N	0,38	N	0,67	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11354	11354	T	G	MI.17578	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	595	199	Y	D	Tac/Gac	-5,96	0	0	possibly_damaging	0,71	deleterious	0,02	neutral	4,63	neutral	-1,67	neutral	-1,07	neutral_impact	0,7	neutral	0,68	neutral	0,47	deleterious	3,74	23,3	0,06	0,35	disease	0,63	disease	0,88	disease	0,59	disease	0,8	6	deleterious	0,98	neutral	0,16	deleterious	1	deleterious	0,74	low_impact	-1,08	medium_impact	-0,75	medium_impact	-0,43	0,16	0,8	14,81	11,39	N	0,32	N	0,85	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11355	11355	A	T	MI.17579	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	596	199	Y	F	tAc/tTc	1,87	0,95	0	possibly_damaging	0,49	neutral	0,27	neutral	4,77	neutral	2,82	neutral	-0,04	neutral_impact	-1,66	neutral	0,79	neutral	0,86	neutral	1,61	13,91	0,24	0,45	neutral	0,33	disease	0,74	neutral	0,42	disease	0,55	1	neutral	0,7	neutral	0,39	neutral	-3	deleterious	0,53	medium_impact	-0,7	medium_impact	-0,04	low_impact	-2,77	0,32	0,8	14,81	11,39	N	0,36	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8513	8513	C	T	MI.1758	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	148	50	P	S	Ccc/Tcc	-4,27	0	0	probably_damaging	1	neutral	0,42	neutral	1,72	deleterious	-6,57	deleterious	-6,04	low_impact	1,7	neutral	0,99	neutral	0,62	deleterious	2,77	21,2	0,51005936	0,85	disease	0,55	neutral	0,18	disease	0,6	neutral	0,13	7	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,21	medium_impact	0,36	0,21	0,85	1,47	8,21	N	0,47	N	0,7	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11355	11355	A	C	MI.17580	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	596	199	Y	S	tAc/tCc	1,87	0,95	0	benign	0,34	neutral	0,1	neutral	4,67	neutral	1,12	neutral	0,43	neutral_impact	-0,85	neutral	0,77	neutral	0,78	deleterious	1,92	15,73	0,08	0,35	neutral	0,21	disease	0,73	neutral	0,36	disease	0,54	1	neutral	0,88	neutral	0,38	neutral	-6	neutral	0,43	medium_impact	-0,45	medium_impact	-0,33	low_impact	-1,97	0,23	0,8	14,81	11,39	N	0,37	N	0,78	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11355	11355	A	G	MI.17581	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	596	199	Y	C	tAc/tGc	1,87	0,95	0	benign	0,01	neutral	0,9	neutral	4,63	neutral	-0,76	neutral	7,71	neutral_impact	-2,82	neutral	0,73	neutral	0,93	neutral	-1,18	0,01	0,08	0,35	neutral	0,2	neutral	0,34	neutral	0,22	neutral	0,42	2	neutral	0,08	deleterious	0,95	neutral	-6	neutral	0,14	medium_impact	1,16	medium_impact	0,74	low_impact	-3,92	0,09	0,8	14,81	11,39	N	0,32	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11357	11357	A	T	MI.17582	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	598	200	T	S	Aca/Tca	-2,73	0	0	benign	0,3	neutral	0,23	neutral	4,59	neutral	-1,08	neutral	-0,64	neutral_impact	0,76	neutral	0,75	neutral	0,7	neutral	1,32	12,36	0,31	0,45	neutral	0,27	neutral	0,47	neutral	0,49	neutral	0,5	0	neutral	0,72	neutral	0,47	neutral	-6	neutral	0,21	medium_impact	-0,37	medium_impact	-0,09	medium_impact	-0,37	0,3	0,8	14,6	12,64	N	0,41	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11357	11357	A	G	MI.17583	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	598	200	T	A	Aca/Gca	-2,73	0	0	benign	0,12	deleterious	0,01	neutral	4,6	neutral	0,37	neutral	-0,33	low_impact	1,07	neutral	0,75	neutral	0,8	neutral	1,41	12,86	0,18	0,45	neutral	0,26	neutral	0,46	neutral	0,49	neutral	0,48	0	deleterious	0,99	neutral	0,45	neutral	-2	neutral	0,14	medium_impact	0,1	medium_impact	-0,92	medium_impact	-0,07	0,28	0,8	14,6	12,64	N	0,42	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11357	11357	A	C	MI.17584	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	598	200	T	P	Aca/Cca	-2,73	0	0	possibly_damaging	0,71	deleterious	0	neutral	4,53	deleterious	-3,01	neutral	-1,47	medium_impact	2,11	neutral	0,67	neutral	0,49	neutral	1,73	14,6	0,05	0,35	disease	0,51	disease	0,85	disease	0,65	disease	0,82	6	deleterious	1	neutral	0,15	deleterious	4	deleterious	0,55	low_impact	-1,08	low_impact	-1,48	medium_impact	0,96	0,2	0,8	14,6	12,64	N	0,32	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11358	11358	C	T	MI.17585	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	599	200	T	M	aCa/aTa	0,26	0	0	benign	0,02	neutral	0,44	neutral	4,58	neutral	-0,55	neutral	2,57	neutral_impact	-1,07	neutral	0,73	neutral	0,96	neutral	-0,2	1,08	0,1	0,4	neutral	0,32	neutral	0,3	neutral	0,28	neutral	0,46	1	neutral	0,54	deleterious	0,71	neutral	-6	neutral	0,12	medium_impact	0,87	medium_impact	0,14	low_impact	-2,18	0,38	0,8	14,6	12,64	N	0,36	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11358	11358	C	A	MI.17586	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	599	200	T	K	aCa/aAa	0,26	0	0	benign	0,34	deleterious	0	neutral	4,54	neutral	-2,59	neutral	-0,92	medium_impact	2,11	neutral	0,71	neutral	0,58	deleterious	2,55	19,76	0,07	0,35	neutral	0,23	disease	0,8	disease	0,64	disease	0,77	5	deleterious	1	neutral	0,33	deleterious	1	neutral	0,3	medium_impact	-0,45	low_impact	-1,48	medium_impact	0,96	0,34	0,8	14,6	12,64	N	0,38	N	0,65	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11360	11360	A	C	MI.17587	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	601	201	M	L	Ata/Cta	-2,96	0	0	benign	0,03	neutral	1	neutral	4,82	neutral	1,81	neutral	-1,08	neutral_impact	0,56	neutral	0,68	neutral	0,91	neutral	1,17	11,61	0,23	0,45	neutral	0,28	disease	0,52	neutral	0,38	neutral	0,46	1	neutral	0,03	deleterious	0,99	neutral	-6	deleterious	0,51	medium_impact	0,7	high_impact	1,88	medium_impact	-0,57	0,17	0,8	18,74	16,33	N	0,37	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11360	11360	A	T	MI.17588	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	601	201	M	L	Ata/Tta	-2,96	0	0	benign	0,03	neutral	1	neutral	4,82	neutral	1,81	neutral	-1,08	neutral_impact	0,56	neutral	0,68	neutral	0,91	neutral	1,36	12,57	0,23	0,45	neutral	0,28	disease	0,52	neutral	0,38	neutral	0,46	1	neutral	0,03	deleterious	0,99	neutral	-6	deleterious	0,51	medium_impact	0,7	high_impact	1,88	medium_impact	-0,57	0,17	0,8	18,74	16,33	N	0,38	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11360	11360	A	G	MI.17589	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	601	201	M	V	Ata/Gta	-2,96	0	0	possibly_damaging	0,54	neutral	0,17	neutral	4,84	neutral	1,35	neutral	-1,82	low_impact	1,65	neutral	0,76	neutral	0,68	neutral	1,46	13,13	0,23	0,45	neutral	0,31	disease	0,74	neutral	0,46	disease	0,55	1	neutral	0,82	neutral	0,32	neutral	-3	deleterious	0,6	medium_impact	-0,78	medium_impact	-0,18	medium_impact	0,51	0,15	0,8	18,74	16,33	N	0,38	N	0,86	polymorphism	1	0,02	rs878928689	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8513	8513	C	G	MI.1759	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	148	50	P	A	Ccc/Gcc	-4,27	0	0	probably_damaging	0,99	neutral	0,53	neutral	1,79	deleterious	-6,3	deleterious	-6,24	medium_impact	2,45	neutral	0,98	neutral	0,63	deleterious	2,06	16,58	0,44721401	0,85	neutral	0,45	neutral	0,17	disease	0,63	neutral	0,18	6	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,75	low_impact	-2,65	medium_impact	0,32	medium_impact	1	0,66	0,85	1,47	8,21	N	0,38	N	0,68	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11361	11361	T	A	MI.17590	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	602	201	M	K	aTa/aAa	0,26	0	0	possibly_damaging	0,9	deleterious	0	neutral	4,54	neutral	-2,69	deleterious	-4,01	high_impact	3,52	neutral	0,73	neutral	0,43	deleterious	4,19	23,8	0,03	0,35	neutral	0,46	disease	0,91	disease	0,68	disease	0,8	6	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,79	low_impact	-1,61	low_impact	-1,48	high_impact	2,36	0,14	0,8	18,74	16,33	N	0,44	N	0,95	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11361	11361	T	C	MI.17591	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	602	201	M	T	aTa/aCa	0,26	0	0	possibly_damaging	0,79	neutral	0,08	neutral	4,61	neutral	-0,94	deleterious	-3,55	low_impact	1,55	neutral	0,71	neutral	0,88	neutral	1,77	14,83	0,1	0,4	neutral	0,32	disease	0,7	neutral	0,45	disease	0,53	1	neutral	0,95	neutral	0,15	neutral	-3	deleterious	0,71	low_impact	-1,26	medium_impact	-0,39	medium_impact	0,41	0,13	0,8	18,74	16,33	N	0,4	N	0,53	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11362	11362	A	T	MI.17592	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	603	201	M	I	atA/atT	2,33	0,05	0,01	possibly_damaging	0,54	neutral	0,39	neutral	4,74	neutral	1,86	neutral	-1,59	low_impact	1,36	neutral	0,71	neutral	0,69	neutral	1,57	13,7	0,24	0,45	neutral	0,33	disease	0,73	neutral	0,42	disease	0,53	1	neutral	0,61	neutral	0,43	neutral	-3	deleterious	0,67	medium_impact	-0,78	medium_impact	0,09	medium_impact	0,22	0,21	0,8	18,74	16,33	N	0,42	N	0,89	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11362	11362	A	C	MI.17593	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	603	201	M	I	atA/atC	2,33	0,05	0,01	possibly_damaging	0,54	neutral	0,39	neutral	4,74	neutral	1,86	neutral	-1,59	low_impact	1,36	neutral	0,71	neutral	0,69	neutral	1,41	12,83	0,24	0,45	neutral	0,33	disease	0,73	neutral	0,42	disease	0,53	1	neutral	0,61	neutral	0,43	neutral	-3	deleterious	0,67	medium_impact	-0,78	medium_impact	0,09	medium_impact	0,22	0,21	0,8	18,74	16,33	N	0,42	N	0,89	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11363	11363	G	T	MI.17594	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	604	202	A	S	Gct/Tct	-0,89	0	0	possibly_damaging	0,86	neutral	0,22	neutral	4,33	neutral	-2,65	neutral	-2,31	medium_impact	2,29	neutral	0,64	neutral	0,53	deleterious	3,65	23,2	0,14	0,4	disease	0,59	disease	0,81	disease	0,55	disease	0,68	4	neutral	0,9	neutral	0,18	NA	0	deleterious	0,81	low_impact	-1,46	medium_impact	-0,11	medium_impact	1,14	0,42	0,8	47,06	9,36	N	0,38	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11363	11363	G	A	MI.17595	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	604	202	A	T	Gct/Act	-0,89	0	0	probably_damaging	0,95	deleterious	0,01	neutral	4,24	deleterious	-3,39	deleterious	-3,09	high_impact	3,53	neutral	0,63	neutral	0,53	deleterious	4,16	23,8	0,1	0,4	disease	0,67	disease	0,83	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,84	low_impact	-1,92	medium_impact	-0,92	high_impact	2,37	0,59	0,8	47,06	9,36	N	0,37	N	0,82	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11363	11363	G	C	MI.17596	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	604	202	A	P	Gct/Cct	-0,89	0	0	probably_damaging	0,99	deleterious	0	neutral	4,18	deleterious	-5,28	deleterious	-3,86	medium_impact	3,37	neutral	0,64	neutral	0,47	deleterious	3,75	23,3	0,04	0,35	disease	0,79	disease	0,87	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,86	low_impact	-2,59	low_impact	-1,48	high_impact	2,21	0,33	0,8	47,06	9,36	N	0,37	N	0,96	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11364	11364	C	T	MI.17597	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	605	202	A	V	gCt/gTt	9,01	1	0	probably_damaging	0,96	neutral	0,1	neutral	4,21	neutral	-1,72	deleterious	-3,09	medium_impact	2,73	damaging	0,58	neutral	0,48	deleterious	4,36	24,1	0,07	0,35	disease	0,78	disease	0,84	disease	0,59	disease	0,61	2	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,83	low_impact	-2,01	medium_impact	-0,33	medium_impact	1,58	0,55	0,8	47,06	9,36	P	0,65	P	0,72	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11364	11364	C	G	MI.17598	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	605	202	A	G	gCt/gGt	9,01	1	0	benign	0,15	neutral	0,09	neutral	4,53	neutral	0,76	deleterious	-3,08	medium_impact	2,19	damaging	0,6	neutral	0,61	deleterious	3,88	23,5	0,18	0,45	disease	0,66	disease	0,76	disease	0,61	disease	0,64	3	neutral	0,9	deleterious	0,47	neutral	-3	deleterious	0,79	medium_impact	-0,01	medium_impact	-0,36	medium_impact	1,04	0,62	0,8	47,06	9,36	P	0,61	P	0,79	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11364	11364	C	A	MI.17599	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	605	202	A	D	gCt/gAt	9,01	1	0	probably_damaging	0,98	deleterious	0	neutral	4,18	deleterious	-5,57	deleterious	-4,63	high_impact	4,34	neutral	0,69	neutral	0,43	deleterious	4,53	24,3	0,03	0,35	neutral	0,49	disease	0,91	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,31	low_impact	-1,48	high_impact	3,17	0,27	0,8	47,06	9,36	P	0,59	P	0,98	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8608	8608	C	T	MI.176	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	82	28	P	S	Cct/Tct	-10,98	0	0	benign	0,02	neutral	0,26	neutral	4,46	neutral	2,22	neutral	1,46	neutral_impact	-0,78	neutral	0,92	neutral	0,96	deleterious	-0,02	2,37	0,58	0,7	neutral	0,24	neutral	0,16	neutral	0,25	neutral	0,3	4	neutral	0,73	deleterious	0,62	neutral	-6	neutral	0,14	medium_impact	0,85	medium_impact	0,04	low_impact	-1,77	0,39	0,9	31,86	20,94	N	0,41	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8514	8514	C	G	MI.1760	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	149	50	P	R	cCc/cGc	0,59	0,09	0	probably_damaging	1	neutral	0,34	neutral	1,63	deleterious	-7,55	deleterious	-6,78	medium_impact	2,59	neutral	0,98	neutral	0,52	deleterious	2,52	19,57	0,42653776	0,85	disease	0,76	neutral	0,36	disease	0,66	neutral	0,25	5	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,13	medium_impact	1,12	0,56	0,85	1,47	8,21	N	0,5	N	0,66	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11366	11366	T	G	MI.17600	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	607	203	F	V	Ttt/Gtt	-8,95	0	0	probably_damaging	1	deleterious	0	neutral	4,51	deleterious	-3,34	deleterious	-5,4	high_impact	4,53	damaging	0,5	damaging	0,1	deleterious	4,03	23,7	0,09	0,35	neutral	0,21	disease	0,87	disease	0,7	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,72	low_impact	-3,54	low_impact	-1,48	high_impact	3,36	0,19	0,8	47,49	9,13	N	0,45	N	0,96	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11366	11366	T	C	MI.17601	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	607	203	F	L	Ttt/Ctt	-8,95	0	0	probably_damaging	1	neutral	0,06	neutral	4,76	neutral	-2,17	deleterious	-4,63	medium_impact	3,08	damaging	0,49	damaging	0,1	deleterious	3,97	23,6	0,16	0,45	neutral	0,28	disease	0,82	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,92	0,38	0,8	47,49	9,13	N	0,37	N	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11366	11366	T	A	MI.17602	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	607	203	F	I	Ttt/Att	-8,95	0	0	probably_damaging	1	deleterious	0	neutral	4,46	deleterious	-3,31	deleterious	-4,63	medium_impact	3,49	damaging	0,52	damaging	0,11	deleterious	4,35	24,1	0,11	0,4	neutral	0,22	disease	0,86	disease	0,7	disease	0,75	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,73	low_impact	-3,54	low_impact	-1,48	high_impact	2,33	0,3	0,8	47,49	9,13	N	0,37	N	0,96	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11367	11367	T	G	MI.17603	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	608	203	F	C	tTt/tGt	5,78	1	0	probably_damaging	1	deleterious	0	neutral	4,39	deleterious	-5,25	deleterious	-6,17	high_impact	4,53	damaging	0,51	damaging	0,07	deleterious	4,04	23,7	0,04	0,35	disease	0,68	disease	0,84	disease	0,72	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	3,36	0,16	0,8	47,49	9,13	P	0,57	P	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11367	11367	T	C	MI.17604	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	608	203	F	S	tTt/tCt	5,78	1	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-4,84	deleterious	-6,17	high_impact	4,53	damaging	0,5	damaging	0,12	deleterious	4,13	23,8	0,03	0,35	neutral	0,32	disease	0,83	disease	0,69	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,54	low_impact	-1,48	high_impact	3,36	0,23	0,8	47,49	9,13	P	0,53	P	0,93	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11367	11367	T	A	MI.17605	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	608	203	F	Y	tTt/tAt	5,78	1	0	probably_damaging	1	deleterious	0	neutral	4,43	deleterious	-4,14	neutral	-2,31	high_impact	3,98	damaging	0,5	damaging	0,09	deleterious	4,14	23,8	0,12	0,4	neutral	0,42	disease	0,77	disease	0,66	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,54	low_impact	-1,48	high_impact	2,81	0,49	0,8	47,49	9,13	P	0,57	P	0,88	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11368	11368	T	A	MI.17606	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	609	203	F	L	ttT/ttA	7,4	1	0	probably_damaging	1	neutral	0,06	neutral	4,76	neutral	-2,17	deleterious	-4,63	medium_impact	3,08	damaging	0,49	damaging	0,1	deleterious	4,4	24,1	0,16	0,45	neutral	0,28	disease	0,82	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,92	0,38	0,8	47,49	9,13	P	0,59	P	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11368	11368	T	G	MI.17607	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	609	203	F	L	ttT/ttG	7,4	1	0	probably_damaging	1	neutral	0,06	neutral	4,76	neutral	-2,17	deleterious	-4,63	medium_impact	3,08	damaging	0,49	damaging	0,1	deleterious	4,27	24	0,16	0,45	neutral	0,28	disease	0,82	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,92	0,38	0,8	47,49	9,13	P	0,59	P	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11369	11369	A	T	MI.17608	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	610	204	M	L	Ata/Tta	-3,42	0	0	benign	0,04	neutral	1	neutral	4,78	neutral	0,52	neutral	-0,96	neutral_impact	-0,4	neutral	0,71	neutral	0,95	deleterious	0,56	7,89	0,31	0,45	neutral	0,29	neutral	0,4	neutral	0,34	neutral	0,44	1	neutral	0,04	deleterious	0,98	neutral	-6	deleterious	0,52	medium_impact	0,58	high_impact	1,88	low_impact	-1,52	0,29	0,8	44,23	9,11	N	0,29	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11369	11369	A	C	MI.17609	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	610	204	M	L	Ata/Cta	-3,42	0	0	benign	0,04	neutral	1	neutral	4,78	neutral	0,52	neutral	-0,96	neutral_impact	-0,4	neutral	0,71	neutral	0,95	deleterious	0,5	7,4	0,31	0,45	neutral	0,29	neutral	0,4	neutral	0,34	neutral	0,44	1	neutral	0,04	deleterious	0,98	neutral	-6	deleterious	0,52	medium_impact	0,58	high_impact	1,88	low_impact	-1,52	0,29	0,8	44,23	9,11	N	0,29	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8514	8514	C	A	MI.1761	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	149	50	P	H	cCc/cAc	0,59	0,09	0	probably_damaging	1	neutral	0,54	neutral	1,61	deleterious	-8,63	deleterious	-7,06	medium_impact	2,17	neutral	0,97	neutral	0,54	deleterious	4,22	23,9	0,47136521	0,85	disease	0,86	neutral	0,3	disease	0,65	neutral	0,19	6	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,33	medium_impact	0,76	0,58	0,85	1,47	8,21	N	0,43	N	0,8	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11369	11369	A	G	MI.17610	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	610	204	M	V	Ata/Gta	-3,42	0	0	possibly_damaging	0,62	deleterious	0,03	neutral	4,62	neutral	-0,37	neutral	-2,27	medium_impact	2,55	neutral	0,78	damaging	0,19	deleterious	2,65	20,5	0,28	0,45	neutral	0,33	disease	0,87	disease	0,57	disease	0,73	5	neutral	0,97	neutral	0,21	deleterious	4	deleterious	0,66	medium_impact	-0,92	medium_impact	-0,64	medium_impact	1,4	0,29	0,8	44,23	9,11	N	0,29	N	0,87	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11370	11370	T	A	MI.17611	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	611	204	M	K	aTa/aAa	0,26	0,02	0	probably_damaging	0,92	deleterious	0	neutral	4,5	neutral	-2,33	deleterious	-4,09	medium_impact	3,36	neutral	0,64	damaging	0,13	deleterious	3,85	23,4	0,03	0,35	disease	0,6	disease	0,93	disease	0,71	disease	0,84	7	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,83	low_impact	-1,71	low_impact	-1,48	high_impact	2,2	0,17	0,8	44,23	9,11	N	0,33	N	0,94	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11370	11370	T	C	MI.17612	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	611	204	M	T	aTa/aCa	0,26	0,02	0	possibly_damaging	0,84	deleterious	0	neutral	4,55	neutral	-1,19	deleterious	-3,82	medium_impact	2,55	neutral	0,67	damaging	0,18	deleterious	2,89	21,8	0,13	0,4	neutral	0,47	disease	0,87	disease	0,63	disease	0,77	5	deleterious	1	neutral	0,08	deleterious	4	deleterious	0,79	low_impact	-1,39	low_impact	-1,48	medium_impact	1,4	0,19	0,8	44,23	9,11	N	0,32	N	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11371	11371	A	T	MI.17613	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	612	204	M	I	atA/atT	5,78	0,99	0	possibly_damaging	0,62	neutral	0,12	neutral	4,6	neutral	-0,4	neutral	-2	medium_impact	2,38	neutral	0,69	damaging	0,15	deleterious	3,48	23,1	0,22	0,45	neutral	0,26	disease	0,89	neutral	0,45	disease	0,68	4	neutral	0,88	neutral	0,25	NA	0	deleterious	0,69	medium_impact	-0,92	medium_impact	-0,28	medium_impact	1,23	0,31	0,8	44,23	9,11	P	0,57	P	0,89	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11371	11371	A	C	MI.17614	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	612	204	M	I	atA/atC	5,78	0,99	0	possibly_damaging	0,62	neutral	0,12	neutral	4,6	neutral	-0,4	neutral	-2	medium_impact	2,38	neutral	0,69	damaging	0,15	deleterious	3,32	22,9	0,22	0,45	neutral	0,26	disease	0,89	neutral	0,45	disease	0,68	4	neutral	0,88	neutral	0,25	NA	0	deleterious	0,69	medium_impact	-0,92	medium_impact	-0,28	medium_impact	1,23	0,31	0,8	44,23	9,11	P	0,57	P	0,89	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11372	11372	G	C	MI.17615	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	613	205	V	L	Gta/Cta	0,49	0,98	0	benign	0,18	deleterious	0	neutral	4,6	neutral	-1,47	neutral	-2,15	high_impact	3,66	neutral	0,68	neutral	0,58	neutral	1,57	13,68	0,24	0,45	neutral	0,23	disease	0,82	disease	0,57	disease	0,7	4	deleterious	1	neutral	0,41	deleterious	2	neutral	0,23	medium_impact	-0,1	low_impact	-1,48	high_impact	2,5	0,42	0,8	23,31	17,27	P	0,55	P	0,58	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11372	11372	G	T	MI.17616	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	613	205	V	L	Gta/Tta	0,49	0,98	0	benign	0,18	deleterious	0	neutral	4,6	neutral	-1,47	neutral	-2,15	high_impact	3,66	neutral	0,68	neutral	0,58	neutral	1,72	14,54	0,24	0,45	neutral	0,23	disease	0,82	disease	0,57	disease	0,7	4	deleterious	1	neutral	0,41	deleterious	2	neutral	0,23	medium_impact	-0,1	low_impact	-1,48	high_impact	2,5	0,42	0,8	23,31	17,27	P	0,55	P	0,58	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11372	11372	G	A	MI.17617	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	613	205	V	M	Gta/Ata	0,49	0,98	0	benign	0,29	neutral	0,07	neutral	4,44	deleterious	-3,04	neutral	-2,23	medium_impact	3,31	neutral	0,71	neutral	0,67	neutral	1,77	14,82	0,19	0,45	neutral	0,27	disease	0,81	disease	0,61	disease	0,7	4	neutral	0,92	neutral	0,39	neutral	-3	neutral	0,2	medium_impact	-0,35	medium_impact	-0,43	high_impact	2,15	0,58	0,8	23,31	17,27	N	0,52	P	0,57	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11373	11373	T	G	MI.17618	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	614	205	V	G	gTa/gGa	2,79	1	0	possibly_damaging	0,73	deleterious	0	neutral	4,47	neutral	-1,08	deleterious	-5,37	high_impact	4,36	neutral	0,68	neutral	0,63	deleterious	3,36	22,9	0,02	0,35	disease	0,76	disease	0,84	disease	0,62	disease	0,73	5	deleterious	1	neutral	0,14	deleterious	5	deleterious	0,61	low_impact	-1,12	low_impact	-1,48	high_impact	3,19	0,23	0,8	23,31	17,27	P	0,55	P	0,93	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11373	11373	T	C	MI.17619	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	614	205	V	A	gTa/gCa	2,79	1	0	benign	0,4	deleterious	0,02	neutral	4,49	neutral	-1,17	deleterious	-3,06	medium_impact	2,56	neutral	0,73	neutral	0,66	neutral	1,75	14,69	0,1	0,4	neutral	0,4	disease	0,64	neutral	0,44	neutral	0,45	1	neutral	0,98	neutral	0,31	deleterious	1	neutral	0,31	medium_impact	-0,55	medium_impact	-0,75	medium_impact	1,41	0,15	0,8	23,31	17,27	P	0,55	P	0,69	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8514	8514	C	T	MI.1762	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	149	50	P	L	cCc/cTc	0,59	0,09	0	probably_damaging	1	neutral	0,66	neutral	1,64	deleterious	-7,4	deleterious	-7,97	medium_impact	3,14	neutral	1	neutral	0,35	deleterious	4,36	24,1	0,59098804	0,85	disease	0,75	neutral	0,34	disease	0,62	neutral	0,24	5	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,45	medium_impact	1,59	0,66	0,85	1,47	8,21	N	0,42	N	0,86	polymorphism	0,79	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11373	11373	T	A	MI.17620	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	614	205	V	E	gTa/gAa	2,79	1	0	possibly_damaging	0,86	deleterious	0	neutral	4,4	deleterious	-4,87	deleterious	-4,61	high_impact	4,36	neutral	0,71	neutral	0,52	deleterious	4,41	24,1	0,02	0,35	disease	0,78	disease	0,89	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,73	low_impact	-1,46	low_impact	-1,48	high_impact	3,19	0,17	0,8	23,31	17,27	P	0,59	P	0,98	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11375	11375	A	G	MI.17621	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	616	206	K	E	Aag/Gag	-6,88	0	0	probably_damaging	1	deleterious	0	neutral	3,17	deleterious	-6,03	deleterious	-3,04	high_impact	4,54	neutral	0,65	damaging	0,2	deleterious	4	23,6	0,04	0,35	neutral	0,41	disease	0,85	disease	0,78	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,37	0,26	0,8	47,71	9,43	N	0,54	P	0,87	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11375	11375	A	C	MI.17622	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	616	206	K	Q	Aag/Cag	-6,88	0	0	probably_damaging	1	deleterious	0	neutral	3,17	deleterious	-6,01	deleterious	-3,06	high_impact	4,54	neutral	0,65	damaging	0,2	deleterious	3,44	23	0,07	0,35	neutral	0,48	disease	0,8	disease	0,77	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,37	0,32	0,8	47,71	9,43	N	0,52	P	0,86	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	A11375C	found in 1 sCJD patient	+	-	Reported	1
chrM	11376	11376	A	T	MI.17623	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	617	206	K	M	aAg/aTg	8,55	1	0	probably_damaging	1	deleterious	0	neutral	3,13	deleterious	-8,49	deleterious	-4,61	high_impact	4,54	neutral	0,69	damaging	0,17	deleterious	3,79	23,4	0,03	0,35	disease	0,53	disease	0,85	disease	0,77	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	3,37	0,19	0,8	47,71	9,43	P	0,57	P	0,42	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11376	11376	A	C	MI.17624	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	617	206	K	T	aAg/aCg	8,55	1	0	probably_damaging	1	deleterious	0	neutral	3,15	deleterious	-6,82	deleterious	-4,6	high_impact	4,54	neutral	0,69	damaging	0,16	deleterious	3,54	23,1	0,04	0,35	neutral	0,26	disease	0,83	disease	0,76	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,37	0,21	0,8	47,71	9,43	P	0,58	P	0,77	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11377	11377	G	C	MI.17625	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	618	206	K	N	aaG/aaC	8,55	1	0,03	probably_damaging	1	deleterious	0	neutral	3,18	deleterious	-6,71	deleterious	-3,83	high_impact	4,2	neutral	0,64	damaging	0,16	deleterious	3,91	23,5	0,07	0,35	disease	0,51	disease	0,82	disease	0,77	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,21	0,8	47,71	9,43	P	0,6	P	0,72	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11377	11377	G	T	MI.17626	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	618	206	K	N	aaG/aaT	8,55	1	0,03	probably_damaging	1	deleterious	0	neutral	3,18	deleterious	-6,71	deleterious	-3,83	high_impact	4,2	neutral	0,64	damaging	0,16	deleterious	4,06	23,7	0,07	0,35	disease	0,51	disease	0,82	disease	0,77	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,21	0,8	47,71	9,43	P	0,6	P	0,72	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11378	11378	A	C	MI.17627	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	619	207	M	L	Ata/Cta	2,1	1	0	benign	0,04	neutral	0,51	neutral	4,84	neutral	1,01	neutral	-2	neutral_impact	0,44	neutral	0,7	neutral	0,76	deleterious	2,95	22	0,32	0,5	neutral	0,34	disease	0,75	disease	0,53	disease	0,52	0	neutral	0,45	deleterious	0,74	neutral	-6	deleterious	0,61	medium_impact	0,58	medium_impact	0,21	medium_impact	-0,69	0,34	0,8	28,76	8,32	N	0,4	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11378	11378	A	G	MI.17628	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	619	207	M	V	Ata/Gta	2,1	1	0	possibly_damaging	0,62	neutral	0,06	neutral	4,68	neutral	0,8	deleterious	-2,88	low_impact	1,88	neutral	0,7	neutral	0,56	deleterious	2,51	19,52	0,23	0,45	neutral	0,35	disease	0,86	disease	0,72	disease	0,77	5	neutral	0,94	neutral	0,22	neutral	-3	deleterious	0,68	medium_impact	-0,92	medium_impact	-0,47	medium_impact	0,73	0,41	0,8	28,76	8,32	N	0,42	N	0,96	polymorphism	1	0,06	rs879106171	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11378	11378	A	T	MI.17629	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	619	207	M	L	Ata/Tta	2,1	1	0	benign	0,04	neutral	0,51	neutral	4,84	neutral	1,01	neutral	-2	neutral_impact	0,44	neutral	0,7	neutral	0,76	deleterious	3,02	22,3	0,32	0,5	neutral	0,34	disease	0,75	disease	0,53	disease	0,52	0	neutral	0,45	deleterious	0,74	neutral	-6	deleterious	0,61	medium_impact	0,58	medium_impact	0,21	medium_impact	-0,69	0,34	0,8	28,76	8,32	N	0,42	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8516	8516	T	G	MI.1763	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	151	51	W	G	Tga/Gga	-4,5	0	0	probably_damaging	0,98	neutral	0,57	neutral	1,49	deleterious	-7,42	deleterious	-12,04	high_impact	3,79	neutral	0,95	neutral	0,44	deleterious	3,97	23,6	0,21986021	0,85	disease	0,85	disease	0,6	disease	0,75	disease	0,68	4	deleterious	0,98	neutral	0,3	deleterious	2	deleterious	0,86	low_impact	-2,36	medium_impact	0,36	high_impact	2,15	0,18	0,85	17,65	8,71	N	0,45	N	0,93	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11379	11379	T	C	MI.17630	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	620	207	M	T	aTa/aCa	3,02	1	0	possibly_damaging	0,84	deleterious	0,04	neutral	4,62	neutral	-0,54	deleterious	-4,41	medium_impact	2,17	neutral	0,72	neutral	0,63	deleterious	2,9	21,9	0,13	0,4	neutral	0,33	disease	0,86	disease	0,68	disease	0,7	4	neutral	0,98	neutral	0,1	deleterious	4	deleterious	0,78	low_impact	-1,39	medium_impact	-0,57	medium_impact	1,02	0,13	0,8	28,76	8,32	N	0,49	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11379	11379	T	A	MI.17631	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	620	207	M	K	aTa/aAa	3,02	1	0	probably_damaging	0,92	deleterious	0	neutral	4,57	neutral	-2,67	deleterious	-4,48	high_impact	3,84	neutral	0,69	neutral	0,46	deleterious	3,92	23,5	0,03	0,35	neutral	0,36	disease	0,92	disease	0,79	disease	0,81	6	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,81	low_impact	-1,71	low_impact	-1,48	high_impact	2,67	0,13	0,8	28,76	8,32	P	0,58	P	1	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11380	11380	A	C	MI.17632	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	621	207	M	I	atA/atC	4,63	1	0,01	possibly_damaging	0,62	neutral	0,51	neutral	4,79	neutral	0,34	deleterious	-2,82	low_impact	1,75	neutral	0,74	neutral	0,62	deleterious	3,37	22,9	0,25	0,45	neutral	0,4	disease	0,87	disease	0,56	disease	0,54	1	neutral	0,6	neutral	0,45	neutral	-3	deleterious	0,75	medium_impact	-0,92	medium_impact	0,21	medium_impact	0,61	0,41	0,8	28,76	8,32	N	0,51	P	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11380	11380	A	T	MI.17633	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	621	207	M	I	atA/atT	4,63	1	0,01	possibly_damaging	0,62	neutral	0,51	neutral	4,79	neutral	0,34	deleterious	-2,82	low_impact	1,75	neutral	0,74	neutral	0,62	deleterious	3,45	23	0,25	0,45	neutral	0,4	disease	0,87	disease	0,56	disease	0,54	1	neutral	0,6	neutral	0,45	neutral	-3	deleterious	0,75	medium_impact	-0,92	medium_impact	0,21	medium_impact	0,61	0,41	0,8	28,76	8,32	P	0,53	P	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11381	11381	C	T	MI.17634	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	622	208	P	S	Cct/Tct	-0,89	0,02	0	probably_damaging	1	deleterious	0	neutral	4,51	neutral	-1,51	deleterious	-6,16	high_impact	4,2	damaging	0,47	damaging	0,1	deleterious	3,88	23,5	0,07	0,35	neutral	0,3	disease	0,81	disease	0,68	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,1	0,8	46,84	9,48	N	0,46	N	0,71	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11381	11381	C	G	MI.17635	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	622	208	P	A	Cct/Gct	-0,89	0,02	0	probably_damaging	1	deleterious	0,01	neutral	4,73	neutral	1,42	deleterious	-6,16	high_impact	3,58	damaging	0,47	damaging	0,11	deleterious	3,06	22,4	0,14	0,4	neutral	0,35	disease	0,72	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,75	low_impact	-3,54	medium_impact	-0,92	high_impact	2,42	0,55	0,8	46,84	9,48	N	0,4	N	0,77	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11381	11381	C	A	MI.17636	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	622	208	P	T	Cct/Act	-0,89	0,02	0	probably_damaging	1	deleterious	0	neutral	4,43	deleterious	-3,62	deleterious	-6,16	high_impact	4,55	damaging	0,52	damaging	0,08	deleterious	3,69	23,3	0,05	0,35	neutral	0,4	disease	0,83	disease	0,69	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,38	0,39	0,8	46,84	9,48	N	0,43	N	0,89	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11382	11382	C	G	MI.17637	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	623	208	P	R	cCt/cGt	7,17	1	0	probably_damaging	1	deleterious	0	neutral	4,34	deleterious	-4,98	deleterious	-6,93	high_impact	4,55	damaging	0,56	damaging	0,07	deleterious	3,53	23,1	0,03	0,35	disease	0,59	disease	0,91	disease	0,79	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,38	0,2	0,8	46,84	9,48	P	0,61	P	0,58	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11382	11382	C	T	MI.17638	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	623	208	P	L	cCt/cTt	7,17	1	0	probably_damaging	1	deleterious	0	neutral	4,34	deleterious	-3,91	deleterious	-7,7	high_impact	4,2	damaging	0,47	damaging	0,06	deleterious	4,24	23,9	0,03	0,35	neutral	0,25	disease	0,89	disease	0,68	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,57	0,8	46,84	9,48	P	0,6	P	0,97	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11382	11382	C	A	MI.17639	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	623	208	P	H	cCt/cAt	7,17	1	0	probably_damaging	1	deleterious	0	neutral	4,33	deleterious	-5,98	deleterious	-6,92	high_impact	4,55	damaging	0,49	damaging	0,06	deleterious	4,02	23,6	0,04	0,35	disease	0,67	disease	0,86	disease	0,79	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	3,38	0,24	0,8	46,84	9,48	P	0,59	P	0,7	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8516	8516	T	C	MI.1764	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	151	51	W	R	Tga/Cga	-4,5	0	0	probably_damaging	1	neutral	0,69	neutral	1,47	deleterious	-7,63	deleterious	-12,77	high_impact	3,79	neutral	0,91	damaging	0,27	deleterious	3,61	23,2	0,25608775	0,85	disease	0,89	disease	0,65	disease	0,78	disease	0,67	3	deleterious	0,99	neutral	0,35	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,49	high_impact	2,15	0,17	0,85	17,65	8,71	N	0,45	N	0,97	polymorphism	1	0,41	rs878928585	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11384	11384	C	T	MI.17640	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	625	209	L	F	Ctt/Ttt	-9,41	0	0	probably_damaging	1	deleterious	0,02	neutral	4,46	deleterious	-3,21	deleterious	-3	medium_impact	3,12	neutral	0,67	damaging	0,15	deleterious	3,95	23,6	0,12	0,4	disease	0,57	disease	0,66	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,96	0,52	0,8	46,19	8,18	N	0,29	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11384	11384	C	A	MI.17641	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	625	209	L	I	Ctt/Att	-9,41	0	0	probably_damaging	1	neutral	0,27	neutral	4,6	neutral	-1,17	neutral	-1,5	low_impact	1,69	neutral	0,74	damaging	0,26	deleterious	4,14	23,8	0,3	0,45	neutral	0,22	disease	0,58	neutral	0,35	neutral	0,45	1	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	-0,04	medium_impact	0,55	0,61	0,8	46,19	8,18	N	0,34	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11384	11384	C	G	MI.17642	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	625	209	L	V	Ctt/Gtt	-9,41	0	0	probably_damaging	1	neutral	0,34	neutral	4,56	neutral	-1,44	neutral	-2,23	low_impact	1,77	neutral	0,77	damaging	0,19	deleterious	3,45	23	0,28	0,45	neutral	0,36	disease	0,6	disease	0,53	neutral	0,47	1	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	0,04	medium_impact	0,63	0,5	0,8	46,19	8,18	N	0,26	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11385	11385	T	A	MI.17643	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	626	209	L	H	cTt/cAt	-0,66	0	0	probably_damaging	1	deleterious	0	neutral	4,43	deleterious	-5,24	deleterious	-5,27	high_impact	3,82	neutral	0,71	damaging	0,13	deleterious	4	23,6	0,05	0,35	neutral	0,2	disease	0,8	disease	0,67	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,54	low_impact	-1,48	high_impact	2,65	0,24	0,8	46,19	8,18	N	0,37	N	0,96	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11385	11385	T	C	MI.17644	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	626	209	L	P	cTt/cCt	-0,66	0	0	probably_damaging	1	deleterious	0	neutral	4,43	deleterious	-4,97	deleterious	-5,27	high_impact	3,82	neutral	0,61	damaging	0,14	deleterious	3,68	23,3	0,02	0,35	disease	0,73	disease	0,84	disease	0,65	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	2,65	0,13	0,8	46,19	8,18	N	0,32	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11385	11385	T	G	MI.17645	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	626	209	L	R	cTt/cGt	-0,66	0	0	probably_damaging	1	deleterious	0	neutral	4,44	deleterious	-4,69	deleterious	-4,5	high_impact	3,82	neutral	0,61	damaging	0,13	deleterious	3,97	23,6	0,03	0,35	disease	0,6	disease	0,91	disease	0,76	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	2,65	0,16	0,8	46,19	8,18	N	0,39	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11387	11387	T	C	MI.17646	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	628	210	Y	H	Tac/Cac	-3,19	0	0	probably_damaging	1	deleterious	0	neutral	4,53	neutral	-1,82	deleterious	-3,85	high_impact	4,16	damaging	0,49	damaging	0,06	deleterious	3,51	23,1	0,15	0,45	disease	0,74	disease	0,79	disease	0,8	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,99	0,18	0,8	47,28	9,26	N	0,45	N	0,97	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11387	11387	T	G	MI.17647	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	628	210	Y	D	Tac/Gac	-3,19	0	0	probably_damaging	1	deleterious	0	neutral	4,52	neutral	-2,51	deleterious	-7,7	high_impact	4,16	damaging	0,47	damaging	0,07	deleterious	3,88	23,5	0,04	0,35	disease	0,83	disease	0,88	disease	0,8	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,99	0,14	0,8	47,28	9,26	N	0,49	N	0,99	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11387	11387	T	A	MI.17648	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	628	210	Y	N	Tac/Aac	-3,19	0	0	probably_damaging	1	deleterious	0	neutral	4,53	neutral	-1,58	deleterious	-6,93	high_impact	4,16	damaging	0,5	damaging	0,07	deleterious	3,96	23,6	0,08	0,35	neutral	0,44	disease	0,83	disease	0,73	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,54	low_impact	-1,48	high_impact	2,99	0,13	0,8	47,28	9,26	N	0,4	N	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11388	11388	A	G	MI.17649	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	629	210	Y	C	tAc/tGc	5,78	1	0	probably_damaging	1	deleterious	0	neutral	4,53	neutral	-1,63	deleterious	-6,93	high_impact	4,16	damaging	0,49	damaging	0,05	deleterious	3,52	23,1	0,05	0,35	disease	0,9	disease	0,84	disease	0,76	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	2,99	0,09	0,8	47,28	9,26	P	0,62	P	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8517	8517	G	C	MI.1765	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	152	51	W	S	tGa/tCa	7,53	1	0	probably_damaging	0,99	neutral	0,9	neutral	1,64	deleterious	-7,53	deleterious	-12,81	high_impact	3,79	neutral	0,9	neutral	0,38	deleterious	4,08	23,7	0,18580261	0,85	disease	0,88	disease	0,71	disease	0,75	disease	0,76	5	deleterious	0,99	neutral	0,46	deleterious	2	deleterious	0,89	low_impact	-2,65	medium_impact	0,83	high_impact	2,15	0,19	0,85	17,65	8,71	P	0,58	P	0,95	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11388	11388	A	T	MI.17650	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	629	210	Y	F	tAc/tTc	5,78	1	0	probably_damaging	1	neutral	0,35	neutral	4,73	neutral	3,73	deleterious	-3,08	low_impact	1,58	damaging	0,52	damaging	0,11	deleterious	3,35	22,9	0,24	0,45	neutral	0,46	disease	0,57	disease	0,55	neutral	0,44	1	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,78	low_impact	-3,54	medium_impact	0,05	medium_impact	0,44	0,44	0,8	47,28	9,26	P	0,58	P	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11388	11388	A	C	MI.17651	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	629	210	Y	S	tAc/tCc	5,78	1	0	probably_damaging	1	deleterious	0	neutral	4,57	neutral	-0,2	deleterious	-6,93	high_impact	4,16	damaging	0,49	damaging	0,08	deleterious	3,71	23,3	0,06	0,35	disease	0,73	disease	0,81	disease	0,71	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,99	0,18	0,8	47,28	9,26	P	0,62	P	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11390	11390	G	C	MI.17652	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	631	211	G	R	Gga/Cga	-6,19	0	0	probably_damaging	1	neutral	0,34	neutral	4,55	neutral	-2,52	deleterious	-6,15	high_impact	3,76	neutral	0,63	neutral	0,3	deleterious	3,96	23,6	0,02	0,35	disease	0,6	disease	0,92	disease	0,8	disease	0,85	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,88	low_impact	-3,54	medium_impact	0,04	high_impact	2,59	0,41	0,8	47,49	9,47	N	0,4	N	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11390	11390	G	T	MI.17653	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	631	211	G	W	Gga/Tga	-6,19	0	0	probably_damaging	1	neutral	0,18	neutral	4,53	deleterious	-4,79	deleterious	-6,15	medium_impact	3,21	neutral	0,68	damaging	0,28	deleterious	4,42	24,2	0,04	0,35	disease	0,77	disease	0,92	disease	0,75	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,17	high_impact	2,05	0,11	0,8	47,49	9,47	N	0,28	N	1	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11391	11391	G	T	MI.17654	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	632	211	G	V	gGa/gTa	2,56	0,99	0	probably_damaging	1	neutral	0,5	neutral	4,59	neutral	-1,32	deleterious	-6,92	medium_impact	2,87	neutral	0,67	neutral	0,33	deleterious	3,7	23,3	0,03	0,35	neutral	0,23	disease	0,89	disease	0,69	disease	0,76	5	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	0,2	medium_impact	1,71	0,16	0,8	47,49	9,47	N	0,44	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11391	11391	G	C	MI.17655	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	632	211	G	A	gGa/gCa	2,56	0,99	0	probably_damaging	1	neutral	0,51	neutral	4,62	neutral	-1,15	deleterious	-4,61	medium_impact	3,07	neutral	0,7	neutral	0,43	deleterious	3,07	22,4	0,08	0,35	neutral	0,22	disease	0,74	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,21	medium_impact	1,91	0,4	0,8	47,49	9,47	N	0,49	N	0,76	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11391	11391	G	A	MI.17656	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	632	211	G	E	gGa/gAa	2,56	0,99	0	probably_damaging	1	neutral	0,27	neutral	4,56	neutral	-2,71	deleterious	-6,15	high_impact	3,76	neutral	0,67	neutral	0,35	deleterious	3,81	23,4	0,02	0,35	disease	0,63	disease	0,88	disease	0,79	disease	0,84	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	-0,04	high_impact	2,59	0,23	0,8	47,49	9,47	P	0,59	P	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11393	11393	C	A	MI.17657	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	634	212	L	I	Ctc/Atc	-9,64	0	0	possibly_damaging	0,51	neutral	0,17	neutral	4,19	neutral	-2,91	neutral	-0,4	medium_impact	2,19	neutral	0,75	neutral	0,75	neutral	1,04	10,88	0,23	0,45	neutral	0,43	disease	0,54	neutral	0,33	neutral	0,49	0	neutral	0,81	neutral	0,33	NA	0	neutral	0,26	medium_impact	-0,73	medium_impact	-0,18	medium_impact	1,04	0,57	0,8	20,7	24,37	N	0,45	N	0,45	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11393	11393	C	G	MI.17658	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	634	212	L	V	Ctc/Gtc	-9,64	0	0	benign	0,08	neutral	1	neutral	4,23	neutral	-2,31	neutral	-0,7	neutral_impact	0,46	neutral	0,73	neutral	0,93	neutral	-0,99	0,02	0,24	0,45	neutral	0,41	neutral	0,14	neutral	0,29	neutral	0,26	5	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,16	medium_impact	0,28	high_impact	1,88	medium_impact	-0,67	0,63	0,8	20,7	24,37	N	0,32	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11393	11393	C	T	MI.17659	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	634	212	L	F	Ctc/Ttc	-9,64	0	0	probably_damaging	0,93	neutral	0,79	neutral	4,55	neutral	-0,33	neutral	-2,11	low_impact	1,21	neutral	0,76	neutral	0,76	deleterious	3,68	23,3	0,2	0,45	disease	0,56	neutral	0,47	neutral	0,37	disease	0,61	2	neutral	0,92	neutral	0,43	neutral	-2	deleterious	0,62	low_impact	-1,77	medium_impact	0,52	medium_impact	0,07	0,62	0,8	20,7	24,37	N	0,22	N	0,79	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8517	8517	G	T	MI.1766	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	152	51	W	L	tGa/tTa	7,53	1	0	probably_damaging	0,98	neutral	0,79	neutral	1,58	deleterious	-6,33	deleterious	-12,07	high_impact	3,79	neutral	0,89	neutral	0,34	deleterious	4,34	24	0,25608775	0,85	disease	0,79	disease	0,57	disease	0,75	disease	0,68	4	deleterious	0,98	neutral	0,41	deleterious	2	deleterious	0,85	low_impact	-2,36	medium_impact	0,62	high_impact	2,15	0,12	0,85	17,65	8,71	P	0,59	P	0,96	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11394	11394	T	G	MI.17660	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	635	212	L	R	cTc/cGc	-1,81	0	0	probably_damaging	0,93	deleterious	0,02	neutral	4,11	deleterious	-5,63	deleterious	-3,86	high_impact	3,7	neutral	0,73	neutral	0,44	deleterious	4,08	23,7	0,01	0,35	disease	0,72	disease	0,9	disease	0,73	disease	0,83	7	deleterious	0,99	neutral	0,05	deleterious	6	deleterious	0,82	low_impact	-1,77	medium_impact	-0,75	high_impact	2,53	0,21	0,8	20,7	24,37	N	0,36	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11394	11394	T	A	MI.17661	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	635	212	L	H	cTc/cAc	-1,81	0	0	probably_damaging	0,98	deleterious	0,03	neutral	4,11	deleterious	-6,2	deleterious	-4,27	high_impact	3,7	neutral	0,74	neutral	0,48	deleterious	4,26	23,9	0,02	0,35	disease	0,8	disease	0,76	disease	0,69	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,81	low_impact	-2,31	medium_impact	-0,64	high_impact	2,53	0,38	0,8	20,7	24,37	N	0,39	N	0,82	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11394	11394	T	C	MI.17662	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	635	212	L	P	cTc/cCc	-1,81	0	0	probably_damaging	0,95	deleterious	0,01	neutral	4,11	deleterious	-6,14	deleterious	-4,16	high_impact	3,7	neutral	0,64	neutral	0,4	deleterious	3,86	23,5	0,02	0,35	disease	0,81	disease	0,87	disease	0,72	disease	0,82	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,85	low_impact	-1,92	medium_impact	-0,92	high_impact	2,53	0,29	0,8	20,7	24,37	N	0,34	N	0,88	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11396	11396	C	G	MI.17663	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	637	213	H	D	Cac/Gac	-12,86	0	0	possibly_damaging	0,83	deleterious	0	neutral	3,98	deleterious	-5,38	deleterious	-6,93	high_impact	4,51	neutral	0,62	neutral	0,38	deleterious	3,83	23,4	0,04	0,35	disease	0,65	disease	0,84	disease	0,87	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	5	deleterious	0,84	low_impact	-1,37	low_impact	-1,48	high_impact	3,34	0,15	0,8	47,71	9,33	N	0,51	P	0,97	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11396	11396	C	A	MI.17664	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	637	213	H	N	Cac/Aac	-12,86	0	0	possibly_damaging	0,8	deleterious	0	neutral	4	deleterious	-4,75	deleterious	-5,39	high_impact	3,62	damaging	0,52	neutral	0,42	deleterious	3,86	23,5	0,11	0,4	disease	0,57	disease	0,81	disease	0,82	disease	0,78	6	deleterious	1	neutral	0,1	deleterious	5	deleterious	0,83	low_impact	-1,28	low_impact	-1,48	high_impact	2,46	0,2	0,8	47,71	9,33	N	0,44	N	0,97	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11396	11396	C	T	MI.17665	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	637	213	H	Y	Cac/Tac	-12,86	0	0	probably_damaging	0,93	deleterious	0	neutral	4,01	deleterious	-4,86	deleterious	-4,62	high_impact	4,51	damaging	0,56	neutral	0,34	deleterious	3,67	23,2	0,05	0,35	disease	0,53	disease	0,85	disease	0,83	disease	0,81	6	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,84	low_impact	-1,77	low_impact	-1,48	high_impact	3,34	0,27	0,8	47,71	9,33	N	0,55	P	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11397	11397	A	G	MI.17666	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	638	213	H	R	cAc/cGc	7,17	1	0	possibly_damaging	0,83	deleterious	0	neutral	3,99	deleterious	-5,27	deleterious	-6,15	high_impact	3,82	damaging	0,57	neutral	0,37	deleterious	2,96	22,1	0,04	0,35	disease	0,54	disease	0,85	disease	0,85	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	5	deleterious	0,87	low_impact	-1,37	low_impact	-1,48	high_impact	2,65	0,3	0,8	47,71	9,33	P	0,61	P	0,97	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11397	11397	A	T	MI.17667	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	638	213	H	L	cAc/cTc	7,17	1	0	possibly_damaging	0,88	deleterious	0	neutral	3,97	deleterious	-5,26	deleterious	-8,47	high_impact	4,51	damaging	0,56	neutral	0,45	deleterious	3,81	23,4	0,03	0,35	neutral	0,24	disease	0,87	disease	0,83	disease	0,82	6	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,79	low_impact	-1,53	low_impact	-1,48	high_impact	3,34	0,17	0,8	47,71	9,33	P	0,62	P	0,96	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11397	11397	A	C	MI.17668	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	638	213	H	P	cAc/cCc	7,17	1	0	probably_damaging	0,97	deleterious	0	neutral	3,95	deleterious	-6,64	deleterious	-7,7	high_impact	4,51	damaging	0,56	neutral	0,37	deleterious	3,19	22,7	0,02	0,35	disease	0,66	disease	0,86	disease	0,88	disease	0,82	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,88	low_impact	-2,14	low_impact	-1,48	high_impact	3,34	0,12	0,8	47,71	9,33	P	0,65	P	0,95	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11398	11398	C	G	MI.17669	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	639	213	H	Q	caC/caG	8,55	1	0	benign	0,2	deleterious	0	neutral	4,04	deleterious	-4,06	deleterious	-6,16	high_impact	4,51	damaging	0,53	neutral	0,38	deleterious	3,57	23,2	0,05	0,35	disease	0,55	disease	0,8	disease	0,83	disease	0,78	6	deleterious	1	neutral	0,4	deleterious	2	deleterious	0,84	medium_impact	-0,15	low_impact	-1,48	high_impact	3,34	0,31	0,8	47,71	9,33	P	0,6	P	0,93	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8518	8518	A	T	MI.1767	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	153	51	W	C	tgA/tgT	7,3	1	0	probably_damaging	1	neutral	0,19	neutral	1,46	deleterious	-9	deleterious	-12,14	high_impact	3,79	neutral	0,92	damaging	0,24	deleterious	4,23	23,9	0,24424793	0,85	disease	0,94	disease	0,65	disease	0,76	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,06	high_impact	2,15	0,18	0,85	17,65	8,71	P	0,61	P	0,92	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11398	11398	C	A	MI.17670	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	639	213	H	Q	caC/caA	8,55	1	0	benign	0,2	deleterious	0	neutral	4,04	deleterious	-4,06	deleterious	-6,16	high_impact	4,51	damaging	0,53	neutral	0,38	deleterious	3,85	23,4	0,05	0,35	disease	0,55	disease	0,8	disease	0,83	disease	0,78	6	deleterious	1	neutral	0,4	deleterious	2	deleterious	0,84	medium_impact	-0,15	low_impact	-1,48	high_impact	3,34	0,31	0,8	47,71	9,33	P	0,61	P	0,93	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11399	11399	T	G	MI.17671	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	640	214	L	V	Tta/Gta	-1,35	0	0	probably_damaging	1	neutral	0,05	neutral	4,57	neutral	0,63	neutral	-2,31	medium_impact	2,94	damaging	0,42	damaging	0,08	deleterious	3,39	23	0,3	0,45	disease	0,55	disease	0,63	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,78	0,33	0,8	47,49	9,46	N	0,46	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11399	11399	T	A	MI.17672	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	640	214	L	M	Tta/Ata	-1,35	0	0	probably_damaging	1	deleterious	0,03	neutral	4,53	neutral	-0,36	neutral	-1,53	medium_impact	2,9	damaging	0,37	damaging	0,1	deleterious	3,72	23,3	0,29	0,45	disease	0,69	disease	0,58	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,74	0,33	0,8	47,49	9,46	P	0,56	P	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11400	11400	T	G	MI.17673	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	641	214	L	W	tTa/tGa	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-3,75	deleterious	-4,62	high_impact	4,29	damaging	0,43	damaging	0,06	deleterious	3,79	23,4	0,06	0,35	disease	0,88	disease	0,75	disease	0,78	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,12	0,18	0,8	47,49	9,46	P	0,58	P	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11400	11400	T	C	MI.17674	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	641	214	L	S	tTa/tCa	-0,2	0	0	probably_damaging	1	neutral	0,06	neutral	4,5	neutral	-0,22	deleterious	-4,61	medium_impact	2,94	damaging	0,37	damaging	0,1	deleterious	3,76	23,3	0,05	0,35	neutral	0,35	disease	0,76	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,78	0,15	0,8	47,49	9,46	P	0,54	P	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11401	11401	A	C	MI.17675	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	642	214	L	F	ttA/ttC	5,78	0,88	0	probably_damaging	1	deleterious	0,04	neutral	4,61	neutral	0,25	deleterious	-3,08	medium_impact	2,88	damaging	0,43	damaging	0,06	deleterious	3,58	23,2	0,25	0,45	disease	0,74	disease	0,64	disease	0,74	disease	0,68	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,83	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,72	0,37	0,8	47,49	9,46	P	0,61	P	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11401	11401	A	T	MI.17676	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	642	214	L	F	ttA/ttT	5,78	0,88	0	probably_damaging	1	deleterious	0,04	neutral	4,61	neutral	0,25	deleterious	-3,08	medium_impact	2,88	damaging	0,43	damaging	0,06	deleterious	3,59	23,2	0,25	0,45	disease	0,74	disease	0,64	disease	0,74	disease	0,68	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,83	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,72	0,37	0,8	47,49	9,46	P	0,61	P	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11402	11402	T	G	MI.17677	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	643	215	W	G	Tga/Gga	-6,88	0	0	probably_damaging	1	deleterious	0	neutral	0,43	deleterious	-11,95	deleterious	-10,01	high_impact	4,2	damaging	0,48	damaging	0,09	deleterious	3,9	23,5	0,03	0,35	disease	0,54	disease	0,81	disease	0,83	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,06	0,8	47,28	9,32	N	0,43	N	0,97	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11402	11402	T	C	MI.17678	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	643	215	W	R	Tga/Cga	-6,88	0	0	probably_damaging	1	deleterious	0	neutral	0,43	deleterious	-12,85	deleterious	-10,78	high_impact	4,2	damaging	0,49	damaging	0,06	deleterious	3,59	23,2	0,02	0,35	neutral	0,34	disease	0,89	disease	0,86	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,06	0,8	47,28	9,32	N	0,43	N	0,97	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11403	11403	G	C	MI.17679	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	644	215	W	S	tGa/tCa	5,78	1	0	probably_damaging	1	deleterious	0	neutral	0,43	deleterious	-12,98	deleterious	-10,78	high_impact	4,55	damaging	0,45	damaging	0,09	deleterious	4	23,6	0,03	0,35	neutral	0,31	disease	0,88	disease	0,82	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,38	0,06	0,8	47,28	9,32	P	0,54	P	0,93	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8518	8518	A	C	MI.1768	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	153	51	W	C	tgA/tgC	7,3	1	0	probably_damaging	1	neutral	0,19	neutral	1,46	deleterious	-9	deleterious	-12,14	high_impact	3,79	neutral	0,92	damaging	0,24	deleterious	4,13	23,8	0,24424793	0,85	disease	0,94	disease	0,65	disease	0,76	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,06	high_impact	2,15	0,18	0,85	17,65	8,71	P	0,61	P	0,92	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11403	11403	G	T	MI.17680	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	644	215	W	L	tGa/tTa	5,78	1	0	probably_damaging	1	deleterious	0	neutral	0,43	deleterious	-11,93	deleterious	-10,01	high_impact	4,55	damaging	0,47	damaging	0,05	deleterious	4,24	23,9	0,03	0,35	disease	0,53	disease	0,82	disease	0,82	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,38	0,05	0,8	47,28	9,32	P	0,58	P	0,97	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11404	11404	A	T	MI.17681	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	645	215	W	C	tgA/tgT	9,01	1	0	probably_damaging	1	deleterious	0	neutral	0,43	deleterious	-13,81	deleterious	-10,01	high_impact	4,55	damaging	0,44	damaging	0,04	deleterious	4,13	23,8	0,03	0,35	disease	0,84	disease	0,85	disease	0,84	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,38	0,06	0,8	47,28	9,32	P	0,57	P	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11404	11404	A	C	MI.17682	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	645	215	W	C	tgA/tgC	9,01	1	0	probably_damaging	1	deleterious	0	neutral	0,43	deleterious	-13,81	deleterious	-10,01	high_impact	4,55	damaging	0,44	damaging	0,04	deleterious	3,99	23,6	0,03	0,35	disease	0,84	disease	0,85	disease	0,84	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,38	0,06	0,8	47,28	9,32	P	0,57	P	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11405	11405	C	A	MI.17683	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	646	216	L	I	Ctc/Atc	5,55	1	0	probably_damaging	1	deleterious	0	neutral	4,1	deleterious	-4,54	neutral	-1,54	high_impact	4,54	damaging	0,43	damaging	0,09	deleterious	4,08	23,7	0,19	0,45	neutral	0,47	disease	0,6	disease	0,72	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	3,37	0,51	0,8	46,62	9,3	P	0,73	P	0,87	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11405	11405	C	G	MI.17684	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	646	216	L	V	Ctc/Gtc	5,55	1	0	probably_damaging	1	deleterious	0	neutral	4,04	deleterious	-4,1	neutral	-2,31	high_impact	4,54	damaging	0,38	damaging	0,08	deleterious	3,44	23	0,15	0,45	neutral	0,47	disease	0,57	disease	0,73	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	3,37	0,52	0,8	46,62	9,3	P	0,77	P	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11405	11405	C	T	MI.17685	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	646	216	L	F	Ctc/Ttc	5,55	1	0	probably_damaging	1	deleterious	0	neutral	4	deleterious	-5,92	deleterious	-3,08	high_impact	4,54	damaging	0,4	damaging	0,07	deleterious	4,02	23,6	0,1	0,4	neutral	0,38	disease	0,63	disease	0,73	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	3,37	0,41	0,8	46,62	9,3	P	0,72	P	0,99	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11406	11406	T	C	MI.17686	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	647	216	L	P	cTc/cCc	-1,35	0	0	probably_damaging	1	deleterious	0	neutral	3,93	deleterious	-7,44	deleterious	-5,38	high_impact	4,19	damaging	0,33	damaging	0,07	deleterious	3,97	23,6	0,02	0,35	disease	0,81	disease	0,73	disease	0,72	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,02	0,16	0,8	46,62	9,3	P	0,54	P	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11406	11406	T	G	MI.17687	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	647	216	L	R	cTc/cGc	-1,35	0	0	probably_damaging	1	deleterious	0	neutral	3,93	deleterious	-6,83	deleterious	-4,61	high_impact	4,54	damaging	0,41	damaging	0,06	deleterious	4,23	23,9	0,01	0,35	disease	0,73	disease	0,83	disease	0,82	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,37	0,15	0,8	46,62	9,3	P	0,61	P	1	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11406	11406	T	A	MI.17688	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	647	216	L	H	cTc/cAc	-1,35	0	0	probably_damaging	1	deleterious	0	neutral	3,93	deleterious	-7,39	deleterious	-5,38	high_impact	4,54	damaging	0,4	damaging	0,06	deleterious	4,34	24	0,02	0,35	disease	0,54	disease	0,75	disease	0,8	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	3,37	0,28	0,8	46,62	9,3	P	0,58	P	0,96	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11408	11408	C	T	MI.17689	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	649	217	P	S	Cct/Tct	-12,63	0	0	probably_damaging	0,98	deleterious	0	neutral	4,1	deleterious	-5,35	deleterious	-6,12	high_impact	4,17	neutral	0,63	neutral	0,57	deleterious	3,93	23,5	0,05	0,35	neutral	0,37	disease	0,8	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,31	low_impact	-1,48	high_impact	3	0,06	0,8	46,62	9,41	N	0,44	N	0,71	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8519	8519	G	A	MI.1769	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	154	52	E	K	Gaa/Aaa	8,69	1	0	probably_damaging	0,97	neutral	0,92	neutral	1,84	neutral	-2,3	deleterious	-3,08	medium_impact	2,19	neutral	1	neutral	0,68	deleterious	4,52	24,3	0,61315205	0,85	disease	0,6	disease	0,54	neutral	0,45	neutral	0,45	1	neutral	0,97	deleterious	0,48	deleterious	1	deleterious	0,8	low_impact	-2,19	medium_impact	0,89	medium_impact	0,78	0,75	0,85	NA	NA	N	0,53	P	0,71	disease_causing	0,94	0,12	rs878853091	Likely benign	not_provided	RCV000224901.1	MedGen	.	.	.	1,93	G8519A	Susceptibility to bullous pemphigoid	+	-	Reported	1
chrM	11408	11408	C	A	MI.17690	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	649	217	P	T	Cct/Act	-12,63	0	0	probably_damaging	0,97	deleterious	0,02	neutral	4,14	deleterious	-5,45	deleterious	-6,13	high_impact	3,62	neutral	0,63	neutral	0,46	deleterious	3,75	23,3	0,05	0,35	disease	0,57	disease	0,81	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,82	low_impact	-2,14	medium_impact	-0,75	high_impact	2,46	0,35	0,8	46,62	9,41	N	0,35	N	0,89	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11408	11408	C	G	MI.17691	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	649	217	P	A	Cct/Gct	-12,63	0	0	possibly_damaging	0,89	deleterious	0	neutral	4,16	deleterious	-4,58	deleterious	-6,13	high_impact	4,17	damaging	0,59	neutral	0,53	deleterious	3,11	22,5	0,08	0,35	disease	0,51	disease	0,67	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,79	low_impact	-1,57	low_impact	-1,48	high_impact	3	0,53	0,8	46,62	9,41	N	0,45	N	0,77	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11409	11409	C	A	MI.17692	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	650	217	P	H	cCt/cAt	4,4	0,99	0	probably_damaging	0,99	deleterious	0	neutral	4,08	deleterious	-6,78	deleterious	-6,9	high_impact	4,17	damaging	0,57	neutral	0,39	deleterious	3,98	23,6	0,04	0,35	neutral	0,37	disease	0,84	disease	0,81	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,59	low_impact	-1,48	high_impact	3	0,17	0,8	46,62	9,41	P	0,54	P	0,7	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11409	11409	C	G	MI.17693	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	650	217	P	R	cCt/cGt	4,4	0,99	0	probably_damaging	0,98	deleterious	0	neutral	4,09	deleterious	-5,91	deleterious	-6,9	high_impact	4,17	neutral	0,63	neutral	0,45	deleterious	3,64	23,2	0,03	0,35	disease	0,59	disease	0,87	disease	0,82	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,31	low_impact	-1,48	high_impact	3	0,16	0,8	46,62	9,41	P	0,6	P	0,58	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11409	11409	C	T	MI.17694	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	650	217	P	L	cCt/cTt	4,4	0,99	0	benign	0,29	deleterious	0,02	neutral	4,22	deleterious	-4,7	deleterious	-7,67	medium_impact	3,21	damaging	0,5	neutral	0,48	deleterious	4,35	24,1	0,03	0,35	disease	0,7	disease	0,86	disease	0,71	disease	0,77	5	neutral	0,98	neutral	0,37	deleterious	1	deleterious	0,85	medium_impact	-0,35	medium_impact	-0,75	high_impact	2,05	0,61	0,8	46,62	9,41	P	0,57	P	0,97	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11411	11411	A	G	MI.17695	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	652	218	K	E	Aaa/Gaa	-20	0	0	probably_damaging	1	deleterious	0	neutral	4,56	neutral	0	deleterious	-3,04	medium_impact	2,78	neutral	0,61	damaging	0,18	deleterious	4,04	23,7	0,18	0,45	neutral	0,46	disease	0,86	disease	0,67	disease	0,74	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	medium_impact	1,62	0,43	0,8	47,28	9,23	N	0,33	N	0,87	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11411	11411	A	C	MI.17696	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	652	218	K	Q	Aaa/Caa	-20	0	0	probably_damaging	1	neutral	0,05	neutral	4,48	neutral	-0,85	deleterious	-3,04	medium_impact	3,5	neutral	0,62	damaging	0,17	deleterious	3,42	23	0,38	0,5	disease	0,51	disease	0,82	disease	0,64	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,52	high_impact	2,34	0,3	0,8	47,28	9,23	N	0,33	N	0,86	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11412	11412	A	T	MI.17697	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	653	218	K	M	aAa/aTa	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,41	neutral	-2,96	deleterious	-4,56	high_impact	3,84	neutral	0,66	damaging	0,17	deleterious	4,01	23,6	0,08	0,35	neutral	0,41	disease	0,83	disease	0,57	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	2,67	0,22	0,8	47,28	9,23	P	0,56	P	0,42	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11412	11412	A	C	MI.17698	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	653	218	K	T	aAa/aCa	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,5	neutral	-0,78	deleterious	-4,56	high_impact	3,58	neutral	0,62	damaging	0,17	deleterious	3,71	23,3	0,07	0,35	neutral	0,42	disease	0,84	disease	0,64	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	2,42	0,2	0,8	47,28	9,23	P	0,58	P	0,77	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11413	11413	A	T	MI.17699	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	654	218	K	N	aaA/aaT	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,45	neutral	-0,54	deleterious	-3,8	high_impact	4,04	neutral	0,61	damaging	0,15	deleterious	3,96	23,6	0,46	0,55	disease	0,54	disease	0,83	disease	0,66	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,87	0,32	0,8	47,28	9,23	P	0,61	P	0,72	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8608	8608	C	A	MI.177	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	82	28	P	T	Cct/Act	-10,98	0	0	benign	0,38	neutral	0,17	neutral	4,47	neutral	2,5	neutral	1,35	neutral_impact	-0,5	neutral	0,91	neutral	0,95	deleterious	0,04	3,01	0,38	0,65	neutral	0,43	neutral	0,1	neutral	0,12	neutral	0,32	4	neutral	0,8	neutral	0,4	neutral	-6	neutral	0,33	medium_impact	-0,55	medium_impact	-0,1	low_impact	-1,53	0,77	0,9	31,86	20,94	P	0,53	P	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8519	8519	G	C	MI.1770	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	154	52	E	Q	Gaa/Caa	8,69	1	0	probably_damaging	0,98	neutral	0,57	neutral	1,81	neutral	-2,23	neutral	-1,93	medium_impact	2,09	neutral	0,99	neutral	0,7	neutral	1,77	14,8	0,62290357	0,85	disease	0,64	neutral	0,12	neutral	0,4	neutral	0,06	9	deleterious	0,98	neutral	0,3	deleterious	1	deleterious	0,71	low_impact	-2,36	medium_impact	0,36	medium_impact	0,69	0,75	0,85	NA	NA	P	0,61	P	0,11	disease_causing	0,77	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11413	11413	A	C	MI.17700	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	654	218	K	N	aaA/aaC	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,45	neutral	-0,54	deleterious	-3,8	high_impact	4,04	neutral	0,61	damaging	0,15	deleterious	3,87	23,5	0,46	0,55	disease	0,54	disease	0,83	disease	0,66	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,87	0,32	0,8	47,28	9,23	P	0,6	P	0,72	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11414	11414	G	C	MI.17701	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	655	219	A	P	Gcc/Ccc	1,64	1	0	probably_damaging	1	deleterious	0	neutral	4,02	deleterious	-6,84	deleterious	-3,8	high_impact	4,52	damaging	0,44	damaging	0,06	deleterious	3,88	23,5	0,02	0,35	disease	0,69	disease	0,83	disease	0,81	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,35	0,31	0,8	46,84	9,32	P	0,66	P	0,96	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11414	11414	G	T	MI.17702	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	655	219	A	S	Gcc/Tcc	1,64	1	0	probably_damaging	1	deleterious	0	neutral	4,23	deleterious	-4,1	neutral	-2,27	high_impact	4,52	damaging	0,46	damaging	0,08	deleterious	3,73	23,3	0,06	0,35	neutral	0,46	disease	0,78	disease	0,68	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	3,35	0,34	0,8	46,84	9,32	P	0,61	P	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11414	11414	G	A	MI.17703	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	655	219	A	T	Gcc/Acc	1,64	1	0	probably_damaging	1	deleterious	0	neutral	4,12	deleterious	-4,01	deleterious	-3,03	medium_impact	3,37	damaging	0,5	damaging	0,06	deleterious	4,37	24,1	0,05	0,35	neutral	0,44	disease	0,8	disease	0,69	disease	0,71	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,21	0,59	0,8	46,84	9,32	P	0,49	N	0,82	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11415	11415	C	G	MI.17704	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	656	219	A	G	gCc/gGc	7,4	1	0	probably_damaging	1	deleterious	0	neutral	4,03	deleterious	-5,5	deleterious	-3,04	high_impact	3,62	damaging	0,47	damaging	0,08	deleterious	4,05	23,7	0,06	0,35	disease	0,62	disease	0,7	disease	0,69	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	2,46	0,52	0,8	46,84	9,32	P	0,61	P	0,79	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11415	11415	C	T	MI.17705	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	656	219	A	V	gCc/gTc	7,4	1	0	probably_damaging	1	neutral	0,08	neutral	4,37	neutral	-2,78	deleterious	-3,04	medium_impact	3,1	damaging	0,45	damaging	0,06	deleterious	4,48	24,2	0,04	0,35	neutral	0,36	disease	0,82	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,39	medium_impact	1,94	0,7	0,85	46,84	9,32	P	0,63	P	0,72	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11415	11415	C	A	MI.17706	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	656	219	A	D	gCc/gAc	7,4	1	0	probably_damaging	1	deleterious	0	neutral	4,01	deleterious	-7,1	deleterious	-4,55	high_impact	4,52	damaging	0,45	damaging	0,05	deleterious	4,7	24,6	0,01	0,35	disease	0,64	disease	0,9	disease	0,79	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,35	0,27	0,8	46,84	9,32	P	0,62	P	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11417	11417	C	A	MI.17707	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	658	220	H	N	Cat/Aat	-3,89	0	0	possibly_damaging	0,64	deleterious	0	neutral	4,45	deleterious	-4,68	deleterious	-5,3	high_impact	4,53	damaging	0,56	neutral	0,43	deleterious	4,06	23,7	0,19	0,45	disease	0,62	disease	0,8	disease	0,77	disease	0,77	5	deleterious	1	neutral	0,18	deleterious	5	deleterious	0,82	medium_impact	-0,95	low_impact	-1,48	high_impact	3,36	0,16	0,8	46,84	9,26	N	0,53	P	0,97	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11417	11417	C	G	MI.17708	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	658	220	H	D	Cat/Gat	-3,89	0	0	benign	0,05	deleterious	0	neutral	4,44	deleterious	-5	deleterious	-6,82	high_impact	4,53	neutral	0,6	neutral	0,4	deleterious	3,93	23,5	0,06	0,35	disease	0,64	disease	0,83	disease	0,8	disease	0,79	6	deleterious	1	deleterious	0,48	deleterious	2	deleterious	0,84	medium_impact	0,48	low_impact	-1,48	high_impact	3,36	0,18	0,8	46,84	9,26	N	0,5	N	0,97	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11417	11417	C	T	MI.17709	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	658	220	H	Y	Cat/Tat	-3,89	0	0	possibly_damaging	0,89	deleterious	0	neutral	4,68	neutral	-0,32	deleterious	-4,55	medium_impact	3	neutral	0,61	neutral	0,33	deleterious	3,8	23,4	0,15	0,4	disease	0,82	disease	0,85	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,06	deleterious	4	deleterious	0,86	low_impact	-1,57	low_impact	-1,48	medium_impact	1,84	0,15	0,8	46,84	9,26	N	0,35	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8520	8520	A	T	MI.1771	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	155	52	E	V	gAa/gTa	-0,1	0	0	probably_damaging	0,99	neutral	0,3	neutral	1,76	deleterious	-4,15	deleterious	-6,19	medium_impact	2,98	neutral	0,99	neutral	0,52	deleterious	4,12	23,8	0,34743468	0,85	disease	0,79	neutral	0,47	disease	0,6	neutral	0,32	4	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,83	low_impact	-2,65	medium_impact	0,08	medium_impact	1,46	0,72	0,85	NA	NA	N	0,5	N	0,72	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11418	11418	A	T	MI.17710	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	659	220	H	L	cAt/cTt	7,17	1	0	possibly_damaging	0,82	deleterious	0	neutral	4,58	neutral	-2,84	deleterious	-8,34	high_impact	4,53	damaging	0,57	neutral	0,45	deleterious	3,95	23,6	0,05	0,35	disease	0,67	disease	0,86	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,09	deleterious	5	deleterious	0,85	low_impact	-1,34	low_impact	-1,48	high_impact	3,36	0,06	0,8	46,84	9,26	P	0,69	P	0,96	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11418	11418	A	G	MI.17711	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	659	220	H	R	cAt/cGt	7,17	1	0	possibly_damaging	0,76	deleterious	0	neutral	4,46	deleterious	-4,43	deleterious	-6,06	high_impact	4,53	neutral	0,62	neutral	0,32	deleterious	3,1	22,5	0,13	0,4	disease	0,65	disease	0,83	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,12	deleterious	5	deleterious	0,87	low_impact	-1,19	low_impact	-1,48	high_impact	3,36	0,38	0,8	46,84	9,26	P	0,62	P	0,97	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11418	11418	A	C	MI.17712	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	659	220	H	P	cAt/cCt	7,17	1	0	probably_damaging	0,93	deleterious	0	neutral	4,45	deleterious	-5,24	deleterious	-7,58	high_impact	4,53	neutral	0,6	neutral	0,38	deleterious	3,43	23	0,06	0,35	disease	0,72	disease	0,85	disease	0,78	disease	0,79	6	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,88	low_impact	-1,77	low_impact	-1,48	high_impact	3,36	0,07	0,8	46,84	9,26	P	0,63	P	0,95	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11419	11419	T	G	MI.17713	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	660	220	H	Q	caT/caG	8,55	1	0	benign	0,13	deleterious	0	neutral	4,45	deleterious	-4,41	deleterious	-6,06	high_impact	4,53	damaging	0,55	neutral	0,41	deleterious	3,62	23,2	0,12	0,4	disease	0,64	disease	0,8	disease	0,77	disease	0,77	5	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,83	medium_impact	0,06	low_impact	-1,48	high_impact	3,36	0,23	0,8	46,84	9,26	P	0,63	P	0,93	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11419	11419	T	A	MI.17714	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	660	220	H	Q	caT/caA	8,55	1	0	benign	0,13	deleterious	0	neutral	4,45	deleterious	-4,41	deleterious	-6,06	high_impact	4,53	damaging	0,55	neutral	0,41	deleterious	3,84	23,4	0,12	0,4	disease	0,64	disease	0,8	disease	0,77	disease	0,77	5	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,83	medium_impact	0,06	low_impact	-1,48	high_impact	3,36	0,23	0,8	46,84	9,26	P	0,64	P	0,93	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11420	11420	G	T	MI.17715	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	661	221	V	F	Gtc/Ttc	-4,35	0	0	probably_damaging	1	deleterious	0	neutral	4,44	deleterious	-3,72	deleterious	-3,79	high_impact	4,49	damaging	0,52	damaging	0,08	deleterious	3,83	23,4	0,1	0,4	disease	0,65	disease	0,88	disease	0,63	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,32	0,2	0,8	47,06	9,31	N	0,41	N	0,97	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11420	11420	G	A	MI.17716	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	661	221	V	I	Gtc/Atc	-4,35	0	0	probably_damaging	1	deleterious	0	neutral	4,5	neutral	-1,6	neutral	-0,76	high_impact	4,13	damaging	0,53	damaging	0,09	deleterious	3,7	23,3	0,33	0,5	neutral	0,28	disease	0,62	neutral	0,48	disease	0,5	0	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,54	low_impact	-1,48	high_impact	2,96	0,68	0,85	47,06	9,31	N	0,43	N	0,44	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11420	11420	G	C	MI.17717	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	661	221	V	L	Gtc/Ctc	-4,35	0	0	probably_damaging	1	deleterious	0,01	neutral	4,47	neutral	-2,28	neutral	-2,27	high_impact	3,68	damaging	0,49	damaging	0,07	deleterious	3,57	23,1	0,21	0,45	neutral	0,42	disease	0,7	disease	0,58	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-3,54	medium_impact	-0,92	high_impact	2,52	0,42	0,8	47,06	9,31	N	0,35	N	0,74	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11421	11421	T	C	MI.17718	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	662	221	V	A	gTc/gCc	6,01	1	0	probably_damaging	1	neutral	0,05	neutral	4,54	neutral	-0,96	deleterious	-3,03	medium_impact	3,06	damaging	0,49	damaging	0,12	deleterious	3,56	23,1	0,3	0,45	disease	0,54	disease	0,62	disease	0,59	disease	0,66	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,9	0,2	0,8	47,06	9,31	P	0,66	P	0,54	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11421	11421	T	A	MI.17719	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	662	221	V	D	gTc/gAc	6,01	1	0	probably_damaging	1	deleterious	0	neutral	4,47	neutral	-2,22	deleterious	-5,3	high_impact	4,13	damaging	0,51	damaging	0,08	deleterious	4,42	24,2	0,05	0,35	disease	0,86	disease	0,88	disease	0,68	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	2,96	0,02	0,8	47,06	9,31	P	0,62	P	0,95	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8520	8520	A	G	MI.1772	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	155	52	E	G	gAa/gGa	-0,1	0	0	probably_damaging	0,98	neutral	0,38	neutral	1,77	deleterious	-3,69	deleterious	-5,97	medium_impact	3,33	neutral	0,99	neutral	0,67	deleterious	4,25	23,9	0,49682067	0,85	disease	0,56	neutral	0,4	disease	0,57	neutral	0,25	5	deleterious	0,98	neutral	0,2	deleterious	1	deleterious	0,77	low_impact	-2,36	medium_impact	0,17	medium_impact	1,76	0,46	0,85	NA	NA	N	0,51	P	0,42	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11421	11421	T	G	MI.17720	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	662	221	V	G	gTc/gGc	6,01	1	0	probably_damaging	1	deleterious	0	neutral	4,48	neutral	-2,14	deleterious	-5,3	high_impact	3,51	damaging	0,5	damaging	0,1	deleterious	3,82	23,4	0,07	0,35	disease	0,77	disease	0,77	disease	0,62	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,35	0,18	0,8	47,06	9,31	P	0,56	P	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11423	11423	G	C	MI.17721	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	664	222	E	Q	Gaa/Caa	-2,73	0	0	probably_damaging	0,95	deleterious	0	neutral	4,48	neutral	-2,47	neutral	-2,27	medium_impact	2,83	damaging	0,44	neutral	0,61	deleterious	3,33	22,9	0,51	0,6	disease	0,71	disease	0,77	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,84	low_impact	-1,92	low_impact	-1,48	medium_impact	1,67	0,33	0,8	47,49	9,45	N	0,48	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11423	11423	G	A	MI.17722	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	664	222	E	K	Gaa/Aaa	-2,73	0	0	possibly_damaging	0,85	deleterious	0	neutral	4,51	neutral	-2,63	deleterious	-3,02	high_impact	3,91	damaging	0,46	neutral	0,43	deleterious	4,51	24,3	0,15	0,4	disease	0,65	disease	0,87	disease	0,75	disease	0,79	6	deleterious	1	neutral	0,08	deleterious	5	deleterious	0,87	low_impact	-1,43	low_impact	-1,48	high_impact	2,74	0,69	0,85	47,49	9,45	P	0,57	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11424	11424	A	T	MI.17723	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	665	222	E	V	gAa/gTa	6,01	1	0	probably_damaging	0,96	deleterious	0	neutral	4,42	deleterious	-3,59	deleterious	-5,29	high_impact	4,46	damaging	0,41	neutral	0,57	deleterious	4,28	24	0,12	0,4	disease	0,53	disease	0,88	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-2,01	low_impact	-1,48	high_impact	3,29	0,44	0,8	47,49	9,45	P	0,79	P	0,8	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11424	11424	A	G	MI.17724	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	665	222	E	G	gAa/gGa	6,01	1	0	benign	0,08	deleterious	0	neutral	4,71	neutral	-1,58	deleterious	-5,29	high_impact	3,56	damaging	0,4	neutral	0,68	deleterious	4,27	23,9	0,21	0,45	disease	0,78	disease	0,76	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,46	deleterious	2	deleterious	0,84	medium_impact	0,28	low_impact	-1,48	high_impact	2,4	0,28	0,8	47,49	9,45	P	0,75	P	0,53	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11424	11424	A	C	MI.17725	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	665	222	E	A	gAa/gCa	6,01	1	0	possibly_damaging	0,74	deleterious	0	neutral	4,53	neutral	-1,28	deleterious	-4,53	high_impact	3,77	damaging	0,48	neutral	0,63	deleterious	3,78	23,4	0,16	0,45	disease	0,59	disease	0,74	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,82	low_impact	-1,14	low_impact	-1,48	high_impact	2,6	0,38	0,8	47,49	9,45	P	0,7	P	0,74	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11425	11425	A	T	MI.17726	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	666	222	E	D	gaA/gaT	8,55	1	0	possibly_damaging	0,85	deleterious	0,01	neutral	4,45	deleterious	-3,45	neutral	-2,27	medium_impact	3,04	damaging	0,53	neutral	0,58	deleterious	3,88	23,5	0,39	0,5	disease	0,76	disease	0,76	disease	0,66	disease	0,71	4	deleterious	0,99	neutral	0,08	deleterious	4	deleterious	0,83	low_impact	-1,43	medium_impact	-0,92	medium_impact	1,88	0,25	0,8	47,49	9,45	P	0,65	P	0,89	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11425	11425	A	C	MI.17727	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	666	222	E	D	gaA/gaC	8,55	1	0	possibly_damaging	0,85	deleterious	0,01	neutral	4,45	deleterious	-3,45	neutral	-2,27	medium_impact	3,04	damaging	0,53	neutral	0,58	deleterious	3,75	23,3	0,39	0,5	disease	0,76	disease	0,76	disease	0,66	disease	0,71	4	deleterious	0,99	neutral	0,08	deleterious	4	deleterious	0,83	low_impact	-1,43	medium_impact	-0,92	medium_impact	1,88	0,25	0,8	47,49	9,45	P	0,64	P	0,89	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11426	11426	G	T	MI.17728	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	667	223	A	S	Gcc/Tcc	-0,2	0,62	0	possibly_damaging	0,86	deleterious	0,03	neutral	4,52	deleterious	-3,54	neutral	-2,27	medium_impact	2,83	neutral	0,64	neutral	0,58	deleterious	3,71	23,3	0,08	0,35	disease	0,78	disease	0,79	disease	0,67	disease	0,72	4	deleterious	0,98	neutral	0,09	deleterious	4	deleterious	0,87	low_impact	-1,46	medium_impact	-0,64	medium_impact	1,67	0,37	0,8	47,06	9,1	N	0,39	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11426	11426	G	A	MI.17729	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	667	223	A	T	Gcc/Acc	-0,2	0,62	0	probably_damaging	0,95	deleterious	0	neutral	4,43	deleterious	-4,45	deleterious	-3,03	high_impact	4,51	damaging	0,54	neutral	0,49	deleterious	4,33	24	0,05	0,35	disease	0,81	disease	0,78	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,88	low_impact	-1,92	low_impact	-1,48	high_impact	3,34	0,6	0,8	47,06	9,1	N	0,5	N	0,82	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8520	8520	A	C	MI.1773	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	155	52	E	A	gAa/gCa	-0,1	0	0	probably_damaging	0,97	neutral	0,73	neutral	1,8	neutral	-2,9	deleterious	-5,17	medium_impact	2,36	neutral	0,98	neutral	0,54	deleterious	3,64	23,2	0,56962521	0,85	disease	0,62	neutral	0,36	disease	0,57	neutral	0,25	5	neutral	0,97	neutral	0,38	deleterious	1	deleterious	0,77	low_impact	-2,19	medium_impact	0,54	medium_impact	0,93	0,7	0,85	NA	NA	N	0,35	N	0,58	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11426	11426	G	C	MI.17730	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	667	223	A	P	Gcc/Ccc	-0,2	0,62	0	probably_damaging	0,99	deleterious	0	neutral	4,61	deleterious	-3,36	deleterious	-3,79	high_impact	4,51	neutral	0,62	neutral	0,43	deleterious	3,87	23,5	0,03	0,35	disease	0,91	disease	0,83	disease	0,66	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,59	low_impact	-1,48	high_impact	3,34	0,51	0,8	47,06	9,1	N	0,45	N	0,96	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11427	11427	C	A	MI.17731	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	668	223	A	D	gCc/gAc	9,01	1	0	probably_damaging	0,98	deleterious	0	neutral	4,39	deleterious	-6,65	deleterious	-4,54	high_impact	4,51	neutral	0,68	neutral	0,44	deleterious	4,67	24,5	0,02	0,35	disease	0,93	disease	0,9	disease	0,79	disease	0,89	8	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,31	low_impact	-1,48	high_impact	3,34	0,28	0,8	47,06	9,1	P	0,66	P	0,98	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11427	11427	C	G	MI.17732	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	668	223	A	G	gCc/gGc	9,01	1	0	benign	0,15	deleterious	0	neutral	4,39	neutral	-2,28	deleterious	-3,02	high_impact	3,82	damaging	0,52	neutral	0,6	deleterious	4,01	23,6	0,09	0,35	disease	0,85	disease	0,72	disease	0,58	disease	0,72	4	deleterious	1	neutral	0,43	deleterious	2	deleterious	0,84	medium_impact	-0,01	low_impact	-1,48	high_impact	2,65	0,66	0,8	47,06	9,1	P	0,6	P	0,79	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11427	11427	C	T	MI.17733	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	668	223	A	V	gCc/gTc	9,01	1	0	probably_damaging	0,96	deleterious	0	neutral	4,46	deleterious	-6,03	deleterious	-3,03	high_impact	4,17	damaging	0,53	neutral	0,48	deleterious	4,46	24,2	0,04	0,35	disease	0,79	disease	0,81	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-2,01	low_impact	-1,48	high_impact	3	0,65	0,8	47,06	9,1	P	0,61	P	0,72	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11429	11429	C	G	MI.17734	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	670	224	P	A	Ccc/Gcc	-7,34	0	0	probably_damaging	1	deleterious	0	neutral	4,43	deleterious	-4,5	deleterious	-6,47	high_impact	4,51	damaging	0,47	damaging	0,11	deleterious	3,12	22,6	0,1	0,4	neutral	0,24	disease	0,68	disease	0,72	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,54	low_impact	-1,48	high_impact	3,34	0,39	0,8	46,84	9,25	N	0,45	N	0,77	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11429	11429	C	T	MI.17735	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	670	224	P	S	Ccc/Tcc	-7,34	0	0	probably_damaging	1	neutral	0,06	neutral	4,51	deleterious	-3,87	deleterious	-6,47	medium_impact	2,82	damaging	0,48	damaging	0,09	deleterious	3,93	23,5	0,1	0,4	neutral	0,25	disease	0,83	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,66	0,14	0,8	46,84	9,25	N	0,32	N	0,71	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11429	11429	C	A	MI.17736	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	670	224	P	T	Ccc/Acc	-7,34	0	0	probably_damaging	1	deleterious	0,01	neutral	4,6	deleterious	-3,08	deleterious	-6,47	high_impact	3,62	damaging	0,52	damaging	0,08	deleterious	3,73	23,3	0,09	0,35	neutral	0,23	disease	0,79	disease	0,67	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-3,54	medium_impact	-0,92	high_impact	2,46	0,37	0,8	46,84	9,25	N	0,29	N	0,89	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11430	11430	C	T	MI.17737	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	671	224	P	L	cCc/cTc	4,4	0,99	0	probably_damaging	1	deleterious	0	neutral	4,4	deleterious	-5,16	deleterious	-8,09	high_impact	4,51	damaging	0,45	damaging	0,06	deleterious	4,43	24,2	0,05	0,35	neutral	0,27	disease	0,85	disease	0,69	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,34	0,46	0,8	46,84	9,25	P	0,56	P	0,97	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11430	11430	C	G	MI.17738	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	671	224	P	R	cCc/cGc	4,4	0,99	0	probably_damaging	1	deleterious	0	neutral	4,4	deleterious	-5	deleterious	-7,28	high_impact	4,51	damaging	0,56	damaging	0,07	deleterious	3,62	23,2	0,04	0,35	disease	0,51	disease	0,88	disease	0,8	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,34	0,22	0,8	46,84	9,25	P	0,62	P	0,58	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11430	11430	C	A	MI.17739	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	671	224	P	H	cCc/cAc	4,4	0,99	0	probably_damaging	1	deleterious	0	neutral	4,4	deleterious	-5,68	deleterious	-7,28	high_impact	3,62	damaging	0,49	damaging	0,06	deleterious	4,05	23,7	0,06	0,35	disease	0,63	disease	0,83	disease	0,81	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,46	0,23	0,8	46,84	9,25	P	0,55	P	0,7	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8521	8521	A	T	MI.1774	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	156	52	E	D	gaA/gaT	0,82	0	0,01	probably_damaging	0,97	neutral	0,61	neutral	1,81	neutral	-2,41	deleterious	-2,61	medium_impact	2,23	neutral	1	neutral	0,57	deleterious	3,78	23,4	0,63950197	0,85	neutral	0,45	neutral	0,35	neutral	0,37	neutral	0,18	6	neutral	0,97	neutral	0,32	deleterious	1	deleterious	0,73	low_impact	-2,19	medium_impact	0,4	medium_impact	0,81	0,81	0,85	NA	NA	N	0,4	N	0,62	polymorphism	1	0,12	rs386829038	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11432	11432	A	G	MI.17740	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	673	225	I	V	Atc/Gtc	-13,55	0	0	probably_damaging	1	neutral	0,99	neutral	4,68	neutral	0,7	neutral	-0,61	low_impact	1,26	neutral	0,62	neutral	0,66	neutral	1,58	13,73	0,34	0,5	neutral	0,45	neutral	0,14	neutral	0,47	neutral	0,28	4	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,64	low_impact	-3,54	medium_impact	1,32	medium_impact	0,12	0,2	0,8	48,58	9,21	N	0,31	N	0,75	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11432	11432	A	T	MI.17741	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	673	225	I	F	Atc/Ttc	-13,55	0	0	probably_damaging	1	deleterious	0,04	neutral	4,62	neutral	-1,54	deleterious	-3,2	medium_impact	3,26	neutral	0,7	neutral	0,43	deleterious	3,9	23,5	0,13	0,4	disease	0,68	disease	0,81	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,84	low_impact	-3,54	medium_impact	-0,57	high_impact	2,1	0,23	0,8	48,58	9,21	N	0,38	N	0,96	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11432	11432	A	C	MI.17742	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	673	225	I	L	Atc/Ctc	-13,55	0	0	probably_damaging	1	neutral	0,13	neutral	4,71	neutral	0,24	neutral	-1,6	medium_impact	1,99	neutral	0,73	neutral	0,46	deleterious	3,83	23,4	0,2	0,45	neutral	0,41	disease	0,63	disease	0,68	disease	0,67	3	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,69	low_impact	-3,54	medium_impact	-0,26	medium_impact	0,84	0,3	0,8	48,58	9,21	N	0,43	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11433	11433	T	G	MI.17743	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	674	225	I	S	aTc/aGc	3,94	0,99	0	probably_damaging	1	neutral	0,07	neutral	4,59	neutral	1,62	deleterious	-4,67	medium_impact	2,71	neutral	0,76	neutral	0,52	deleterious	4,32	24	0,05	0,35	neutral	0,48	disease	0,87	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,43	medium_impact	1,56	0,15	0,8	48,58	9,21	P	0,52	P	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11433	11433	T	A	MI.17744	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	674	225	I	N	aTc/aAc	3,94	0,99	0	probably_damaging	1	deleterious	0	neutral	4,56	neutral	-0,86	deleterious	-5,48	high_impact	3,6	neutral	0,7	neutral	0,44	deleterious	4,46	24,2	0,09	0,35	disease	0,77	disease	0,84	disease	0,72	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	2,44	0,08	0,8	48,58	9,21	P	0,54	P	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11433	11433	T	C	MI.17745	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	674	225	I	T	aTc/aCc	3,94	0,99	0	probably_damaging	1	neutral	0,23	neutral	4,75	neutral	3,36	deleterious	-3,79	low_impact	1,62	neutral	0,71	neutral	0,46	deleterious	3,45	23	0,12	0,4	neutral	0,33	disease	0,72	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	-0,09	medium_impact	0,48	0,12	0,8	48,58	9,21	P	0,51	P	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11434	11434	C	G	MI.17746	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	675	225	I	M	atC/atG	5,78	1	0	probably_damaging	1	deleterious	0,03	neutral	4,59	neutral	-1,37	neutral	-2,3	high_impact	3,6	neutral	0,72	neutral	0,52	deleterious	3,38	23	0,25	0,45	disease	0,67	disease	0,66	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,78	low_impact	-3,54	medium_impact	-0,64	high_impact	2,44	0,21	0,8	48,58	9,21	P	0,65	P	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11434	11434	C	A	MI.17747	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	675	225	I	M	atC/atA	5,78	1	0	probably_damaging	1	deleterious	0,03	neutral	4,59	neutral	-1,37	neutral	-2,3	high_impact	3,6	neutral	0,72	neutral	0,52	deleterious	3,88	23,5	0,25	0,45	disease	0,67	disease	0,66	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,78	low_impact	-3,54	medium_impact	-0,64	high_impact	2,44	0,21	0,8	48,58	9,21	P	0,65	P	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11435	11435	G	A	MI.17748	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	676	226	A	T	Gct/Act	-2,96	0	0	probably_damaging	1	neutral	0,12	neutral	4,61	neutral	-1,79	deleterious	-3,23	medium_impact	3,02	damaging	0,44	damaging	0,06	deleterious	4,21	23,9	0,21	0,45	neutral	0,48	disease	0,81	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	-0,28	medium_impact	1,86	0,64	0,8	47,06	9,45	N	0,43	N	0,82	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11435	11435	G	C	MI.17749	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	676	226	A	P	Gct/Cct	-2,96	0	0	probably_damaging	1	deleterious	0,01	neutral	4,59	neutral	1,17	deleterious	-4,04	medium_impact	2,5	damaging	0,47	damaging	0,06	deleterious	3,8	23,4	0,1	0,4	disease	0,74	disease	0,88	disease	0,81	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,89	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,35	0,49	0,8	47,06	9,45	N	0,39	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8521	8521	A	C	MI.1775	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	156	52	E	D	gaA/gaC	0,82	0	0,01	probably_damaging	0,97	neutral	0,61	neutral	1,81	neutral	-2,41	deleterious	-2,61	medium_impact	2,23	neutral	1	neutral	0,57	deleterious	3,68	23,3	0,63950197	0,85	neutral	0,45	neutral	0,35	neutral	0,37	neutral	0,18	6	neutral	0,97	neutral	0,32	deleterious	1	deleterious	0,73	low_impact	-2,19	medium_impact	0,4	medium_impact	0,81	0,81	0,85	NA	NA	N	0,39	N	0,62	polymorphism	1	0,12	rs386829038	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11435	11435	G	T	MI.17750	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	676	226	A	S	Gct/Tct	-2,96	0	0	probably_damaging	1	neutral	0,38	neutral	4,65	neutral	-1,02	neutral	-2,42	low_impact	1,74	damaging	0,5	damaging	0,09	deleterious	3,7	23,3	0,29	0,45	disease	0,52	disease	0,71	disease	0,65	disease	0,52	0	deleterious	1	neutral	0,19	neutral	-2	deleterious	0,81	low_impact	-3,54	medium_impact	0,08	medium_impact	0,6	0,4	0,8	47,06	9,45	N	0,27	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11436	11436	C	G	MI.17751	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	677	226	A	G	gCt/gGt	7,17	1	0	probably_damaging	1	neutral	0,07	neutral	4,58	neutral	-2,02	deleterious	-3,23	medium_impact	2,35	damaging	0,5	damaging	0,09	deleterious	4,02	23,6	0,28	0,45	disease	0,67	disease	0,79	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,43	medium_impact	1,2	0,5	0,8	47,06	9,45	P	0,59	P	0,79	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11436	11436	C	T	MI.17752	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	677	226	A	V	gCt/gTt	7,17	1	0	probably_damaging	1	deleterious	0,01	neutral	4,8	neutral	-0,3	deleterious	-3,23	medium_impact	2,9	damaging	0,45	damaging	0,07	deleterious	4,44	24,2	0,16	0,45	neutral	0,27	disease	0,86	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,77	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,74	0,62	0,8	47,06	9,45	P	0,6	P	0,72	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11436	11436	C	A	MI.17753	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	677	226	A	D	gCt/gAt	7,17	1	0	probably_damaging	1	deleterious	0	neutral	4,54	deleterious	-3,05	deleterious	-4,84	high_impact	4,21	damaging	0,49	damaging	0,05	deleterious	4,49	24,3	0,03	0,35	disease	0,73	disease	0,92	disease	0,82	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	3,04	0,21	0,8	47,06	9,45	P	0,66	P	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11438	11438	G	C	MI.17754	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	679	227	G	R	Ggg/Cgg	-15,4	0	0	probably_damaging	1	deleterious	0	neutral	4,55	deleterious	-3,3	deleterious	-6,5	high_impact	4,2	damaging	0,55	damaging	0,12	deleterious	4,02	23,6	0,02	0,35	disease	0,57	disease	0,91	disease	0,83	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,53	0,8	46,84	9,36	N	0,42	N	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11438	11438	G	T	MI.17755	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	679	227	G	W	Ggg/Tgg	-15,4	0	0	probably_damaging	1	deleterious	0	neutral	4,51	deleterious	-4,73	deleterious	-6,5	high_impact	4,54	damaging	0,57	damaging	0,11	deleterious	4,46	24,2	0,04	0,35	disease	0,9	disease	0,91	disease	0,78	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,37	0,19	0,8	46,84	9,36	N	0,48	N	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11439	11439	G	T	MI.17756	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	680	227	G	V	gGg/gTg	4,17	1	0	probably_damaging	1	deleterious	0,02	neutral	4,64	neutral	1,58	deleterious	-7,32	medium_impact	3,02	damaging	0,54	damaging	0,11	deleterious	3,81	23,4	0,04	0,35	disease	0,53	disease	0,91	disease	0,75	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,87	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,86	0,12	0,8	46,84	9,36	N	0,48	N	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11439	11439	G	A	MI.17757	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	680	227	G	E	gGg/gAg	4,17	1	0	probably_damaging	1	deleterious	0	neutral	4,58	deleterious	-3,34	deleterious	-6,5	high_impact	4,2	damaging	0,56	damaging	0,12	deleterious	3,89	23,5	0,02	0,35	neutral	0,48	disease	0,9	disease	0,82	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,17	0,8	46,84	9,36	P	0,62	P	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11439	11439	G	C	MI.17758	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	680	227	G	A	gGg/gCg	4,17	1	0	probably_damaging	1	neutral	0,07	neutral	4,6	neutral	-0,33	deleterious	-4,88	medium_impact	3,34	neutral	0,61	damaging	0,15	deleterious	3,09	22,5	0,16	0,45	neutral	0,29	disease	0,75	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	-0,43	high_impact	2,18	0,37	0,8	46,84	9,36	P	0,57	P	0,76	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11441	11441	T	G	MI.17759	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	682	228	S	A	Tca/Gca	-20	0	0	probably_damaging	1	deleterious	0	neutral	4,58	neutral	-0,59	neutral	-2,44	high_impact	3,56	damaging	0,48	damaging	0,15	deleterious	3,73	23,3	0,07	0,35	disease	0,61	disease	0,63	disease	0,64	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	2,4	0,4	0,8	47,93	9,62	N	0,39	N	0,51	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8522	8522	C	A	MI.1776	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	157	53	P	T	Cca/Aca	-0,33	0	0	benign	0,07	neutral	0,41	neutral	2,02	neutral	0,51	neutral	1,08	neutral_impact	-0,96	neutral	0,94	neutral	0,97	neutral	-0,15	1,38	0,37793802	0,85	neutral	0,17	neutral	0,16	neutral	0,19	neutral	0,14	7	neutral	0,54	deleterious	0,67	neutral	-6	neutral	0,12	medium_impact	0,31	medium_impact	0,2	low_impact	-1,92	0,67	0,85	NA	NA	N	0,39	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11441	11441	T	C	MI.17760	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	682	228	S	P	Tca/Cca	-20	0	0	probably_damaging	1	deleterious	0	neutral	4,28	deleterious	-5,65	deleterious	-4,07	high_impact	4,2	damaging	0,38	damaging	0,1	deleterious	4	23,6	0,02	0,35	disease	0,85	disease	0,85	disease	0,8	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,38	0,8	47,93	9,62	P	0,52	P	0,99	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11441	11441	T	A	MI.17761	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	682	228	S	T	Tca/Aca	-20	0	0	probably_damaging	1	deleterious	0,01	neutral	4,39	neutral	-1,91	neutral	-2,44	medium_impact	3,5	damaging	0,46	damaging	0,1	deleterious	3,82	23,4	0,08	0,35	disease	0,66	disease	0,71	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-3,54	medium_impact	-0,92	high_impact	2,34	0,55	0,8	47,93	9,62	N	0,34	N	0,73	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11442	11442	C	G	MI.17762	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	683	228	S	W	tCa/tGa	5,78	1	0	probably_damaging	1	deleterious	0	neutral	4,27	deleterious	-6,88	deleterious	-5,7	high_impact	4,2	damaging	0,45	damaging	0,07	deleterious	4,34	24	0,02	0,35	disease	0,84	disease	0,9	disease	0,74	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,19	0,8	47,93	9,62	P	0,62	P	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11442	11442	C	T	MI.17763	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	683	228	S	L	tCa/tTa	5,78	1	0	probably_damaging	1	deleterious	0	neutral	4,33	deleterious	-3,13	deleterious	-4,88	high_impact	3,85	damaging	0,44	damaging	0,05	deleterious	4,69	24,6	0,02	0,35	neutral	0,32	disease	0,86	disease	0,67	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,54	low_impact	-1,48	high_impact	2,68	0,41	0,8	47,93	9,62	P	0,64	P	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11444	11444	A	G	MI.17764	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	685	229	M	V	Ata/Gta	-14,01	0	0	probably_damaging	0,99	neutral	0,07	neutral	4,6	neutral	1,07	deleterious	-3,26	medium_impact	2,28	damaging	0,6	damaging	0,09	deleterious	2,76	21,1	0,13	0,4	neutral	0,32	disease	0,85	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,68	low_impact	-2,59	medium_impact	-0,43	medium_impact	1,13	0,36	0,8	47,06	9,46	N	0,25	N	0,96	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11444	11444	A	C	MI.17765	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	685	229	M	L	Ata/Cta	-14,01	0	0	probably_damaging	0,98	deleterious	0,01	neutral	4,92	neutral	1,86	neutral	-2,44	high_impact	3,58	neutral	0,63	damaging	0,06	deleterious	3,28	22,8	0,14	0,4	neutral	0,33	disease	0,82	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,6	low_impact	-2,31	medium_impact	-0,92	high_impact	2,42	0,3	0,8	47,06	9,46	N	0,3	N	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11444	11444	A	T	MI.17766	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	685	229	M	L	Ata/Tta	-14,01	0	0	probably_damaging	0,98	deleterious	0,01	neutral	4,92	neutral	1,86	neutral	-2,44	high_impact	3,58	neutral	0,63	damaging	0,06	deleterious	3,42	23	0,14	0,4	neutral	0,33	disease	0,82	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,6	low_impact	-2,31	medium_impact	-0,92	high_impact	2,42	0,3	0,8	47,06	9,46	N	0,31	N	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11445	11445	T	A	MI.17767	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	686	229	M	K	aTa/aAa	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,5	neutral	-2,77	deleterious	-4,89	high_impact	4,48	neutral	0,64	damaging	0,08	deleterious	4,24	23,9	0,02	0,35	disease	0,58	disease	0,92	disease	0,78	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,31	0,15	0,8	47,06	9,46	P	0,65	P	1	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11445	11445	T	C	MI.17768	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	686	229	M	T	aTa/aCa	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,55	neutral	-0,8	deleterious	-4,89	high_impact	4,48	neutral	0,74	damaging	0,1	deleterious	3,01	22,3	0,04	0,35	neutral	0,49	disease	0,86	disease	0,71	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	3,31	0,24	0,8	47,06	9,46	P	0,58	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11446	11446	A	T	MI.17769	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	687	229	M	I	atA/atT	7,4	1	0	probably_damaging	0,99	neutral	0,06	neutral	4,7	neutral	-0,06	deleterious	-3,26	medium_impact	2,75	neutral	0,67	damaging	0,16	deleterious	3,53	23,1	0,16	0,45	neutral	0,38	disease	0,86	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,76	low_impact	-2,59	medium_impact	-0,47	medium_impact	1,6	0,46	0,8	47,06	9,46	P	0,58	P	0,95	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8522	8522	C	G	MI.1777	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	157	53	P	A	Cca/Gca	-0,33	0	0	benign	0,03	neutral	0,5	neutral	2,01	neutral	0,33	neutral	0,22	neutral_impact	0,26	neutral	0,99	neutral	0,77	neutral	-1,26	0,01	0,43104827	0,85	neutral	0,16	neutral	0,1	neutral	0,29	neutral	0,06	9	neutral	0,47	deleterious	0,74	neutral	-6	neutral	0,13	medium_impact	0,68	medium_impact	0,29	medium_impact	-0,88	0,69	0,85	NA	NA	N	0,46	N	0,32	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11446	11446	A	C	MI.17770	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	687	229	M	I	atA/atC	7,4	1	0	probably_damaging	0,99	neutral	0,06	neutral	4,7	neutral	-0,06	deleterious	-3,26	medium_impact	2,75	neutral	0,67	damaging	0,16	deleterious	3,3	22,9	0,16	0,45	neutral	0,38	disease	0,86	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,76	low_impact	-2,59	medium_impact	-0,47	medium_impact	1,6	0,46	0,8	47,06	9,46	P	0,58	P	0,95	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11447	11447	G	C	MI.17771	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	688	230	V	L	Gta/Cta	0,72	0,94	0	benign	0,1	neutral	0,32	neutral	4,92	neutral	1,54	neutral	-2,05	low_impact	1,31	neutral	0,73	neutral	0,53	neutral	1,61	13,89	0,17	0,45	disease	0,65	disease	0,7	neutral	0,41	disease	0,55	1	neutral	0,64	deleterious	0,61	neutral	-6	neutral	0,28	medium_impact	0,18	medium_impact	0,02	medium_impact	0,17	0,24	0,8	18,52	20,7	N	0,35	N	0,5	polymorphism	1	0,03	rs2853492	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11447	11447	G	T	MI.17772	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	688	230	V	L	Gta/Tta	0,72	0,94	0	benign	0,1	neutral	0,32	neutral	4,92	neutral	1,54	neutral	-2,05	low_impact	1,31	neutral	0,73	neutral	0,53	neutral	1,76	14,75	0,17	0,45	disease	0,65	disease	0,7	neutral	0,41	disease	0,55	1	neutral	0,64	deleterious	0,61	neutral	-6	neutral	0,28	medium_impact	0,18	medium_impact	0,02	medium_impact	0,17	0,24	0,8	18,52	20,7	N	0,33	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11447	11447	G	A	MI.17773	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	688	230	V	M	Gta/Ata	0,72	0,94	0	benign	0,1	deleterious	0,01	neutral	4,55	neutral	-1,16	neutral	-2,25	medium_impact	2,52	neutral	0,73	neutral	0,76	neutral	1,79	14,92	0,15	0,45	disease	0,87	disease	0,78	disease	0,61	disease	0,77	5	deleterious	0,99	neutral	0,46	deleterious	1	neutral	0,3	medium_impact	0,18	medium_impact	-0,92	medium_impact	1,37	0,57	0,8	18,52	20,7	N	0,3	N	0,28	polymorphism	1	0,03	rs2853492	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11448	11448	T	G	MI.17774	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	689	230	V	G	gTa/gGa	0,03	0,94	0	possibly_damaging	0,74	deleterious	0	neutral	4,48	deleterious	-3,76	deleterious	-5,72	medium_impact	3,5	neutral	0,7	neutral	0,68	deleterious	2,05	16,5	0,02	0,35	disease	0,95	disease	0,85	disease	0,6	disease	0,84	7	deleterious	1	neutral	0,13	deleterious	4	deleterious	0,47	low_impact	-1,14	low_impact	-1,48	high_impact	2,34	0,31	0,8	18,52	20,7	N	0,4	N	0,95	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11448	11448	T	C	MI.17775	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	689	230	V	A	gTa/gCa	0,03	0,94	0	benign	0,35	deleterious	0,04	neutral	4,52	neutral	-1,97	deleterious	-3,27	medium_impact	3,04	neutral	0,74	neutral	0,71	neutral	1,71	14,45	0,08	0,35	disease	0,82	disease	0,69	disease	0,58	disease	0,7	4	neutral	0,95	neutral	0,35	deleterious	1	neutral	0,33	medium_impact	-0,47	medium_impact	-0,57	medium_impact	1,88	0,12	0,8	18,52	20,7	N	0,38	N	0,82	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11448	11448	T	A	MI.17776	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	689	230	V	E	gTa/gAa	0,03	0,94	0	possibly_damaging	0,8	deleterious	0	neutral	4,48	deleterious	-3,98	deleterious	-4,91	high_impact	3,85	neutral	0,71	neutral	0,55	deleterious	3,12	22,6	0,02	0,35	disease	0,95	disease	0,92	disease	0,72	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	5	deleterious	0,67	low_impact	-1,28	low_impact	-1,48	high_impact	2,68	0,13	0,8	18,52	20,7	N	0,45	N	1	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11450	11450	C	T	MI.17777	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	691	231	L	F	Ctt/Ttt	-7,8	0	0	probably_damaging	0,98	deleterious	0	neutral	4,29	neutral	-2,86	deleterious	-3,27	high_impact	4,05	damaging	0,48	neutral	0,45	deleterious	3,96	23,6	0,05	0,35	disease	0,77	disease	0,75	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,31	low_impact	-1,48	high_impact	2,88	0,42	0,8	46,84	9,41	N	0,43	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11450	11450	C	A	MI.17778	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	691	231	L	I	Ctt/Att	-7,8	0	0	possibly_damaging	0,68	deleterious	0	neutral	4,3	neutral	-2,63	neutral	-1,63	high_impact	4,25	damaging	0,43	neutral	0,52	deleterious	4,15	23,8	0,11	0,4	disease	0,64	disease	0,7	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,16	deleterious	5	deleterious	0,81	low_impact	-1,03	low_impact	-1,48	high_impact	3,08	0,48	0,8	46,84	9,41	P	0,59	P	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11450	11450	C	G	MI.17779	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	691	231	L	V	Ctt/Gtt	-7,8	0	0	benign	0,22	deleterious	0	neutral	4,32	deleterious	-3,01	neutral	-2,45	high_impact	3,8	damaging	0,31	neutral	0,42	deleterious	3,43	23	0,07	0,35	disease	0,62	disease	0,69	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,81	medium_impact	-0,2	low_impact	-1,48	high_impact	2,63	0,56	0,8	46,84	9,41	P	0,6	P	0,89	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8522	8522	C	T	MI.1778	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	157	53	P	S	Cca/Tca	-0,33	0	0	benign	0,01	neutral	0,44	neutral	2,07	neutral	1,3	neutral	0,77	neutral_impact	-0,82	neutral	1	neutral	0,94	neutral	-0,41	0,36	0,41986033	0,85	neutral	0,11	neutral	0,13	neutral	0,18	neutral	0,11	8	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,1	medium_impact	1,14	medium_impact	0,23	low_impact	-1,8	0,4	0,85	NA	NA	N	0,39	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11451	11451	T	G	MI.17780	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	692	231	L	R	cTt/cGt	0,03	0	0	probably_damaging	0,99	deleterious	0	neutral	4,22	deleterious	-4,92	deleterious	-4,91	high_impact	4,6	damaging	0,41	neutral	0,32	deleterious	4,22	23,9	0,02	0,35	disease	0,68	disease	0,89	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,59	low_impact	-1,48	high_impact	3,43	0,12	0,8	46,84	9,41	P	0,67	P	1	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11451	11451	T	C	MI.17781	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	692	231	L	P	cTt/cCt	0,03	0	0	probably_damaging	0,99	deleterious	0	neutral	4,21	deleterious	-5,97	deleterious	-5,73	high_impact	4,25	damaging	0,38	neutral	0,4	deleterious	3,93	23,5	0,02	0,35	disease	0,84	disease	0,84	disease	0,74	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,59	low_impact	-1,48	high_impact	3,08	0,24	0,8	46,84	9,41	P	0,64	P	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11451	11451	T	A	MI.17782	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	692	231	L	H	cTt/cAt	0,03	0	0	probably_damaging	0,99	deleterious	0	neutral	4,43	neutral	-1,12	deleterious	-5,73	high_impact	3,8	damaging	0,39	neutral	0,38	deleterious	4,18	23,8	0,02	0,35	disease	0,83	disease	0,82	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,59	low_impact	-1,48	high_impact	2,63	0,18	0,8	46,84	9,41	P	0,61	P	0,96	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11453	11453	G	C	MI.17783	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	694	232	A	P	Gcc/Ccc	-5,5	0	0	probably_damaging	1	deleterious	0	neutral	4,16	deleterious	-5,96	deleterious	-4,11	high_impact	4,59	damaging	0,49	neutral	0,31	deleterious	3,83	23,4	0,03	0,35	disease	0,85	disease	0,91	disease	0,78	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,39	0,8	45,97	9,16	P	0,55	P	0,96	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11453	11453	G	A	MI.17784	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	694	232	A	T	Gcc/Acc	-5,5	0	0	probably_damaging	1	deleterious	0	neutral	4,2	deleterious	-3,96	deleterious	-3,28	high_impact	4,59	damaging	0,42	damaging	0,28	deleterious	4,26	23,9	0,07	0,35	disease	0,65	disease	0,85	disease	0,68	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,66	0,8	45,97	9,16	P	0,58	P	0,82	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11453	11453	G	T	MI.17785	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	694	232	A	S	Gcc/Tcc	-5,5	0	0	probably_damaging	1	neutral	0,05	neutral	4,41	neutral	-0,88	neutral	-2,46	medium_impact	3,15	damaging	0,51	neutral	0,43	deleterious	3,72	23,3	0,21	0,45	neutral	0,5	disease	0,88	disease	0,63	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,99	0,42	0,8	45,97	9,16	N	0,41	N	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11454	11454	C	A	MI.17786	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	695	232	A	D	gCc/gAc	9,01	1	0	probably_damaging	1	deleterious	0	neutral	4,18	deleterious	-5,44	deleterious	-4,92	high_impact	4,59	damaging	0,54	neutral	0,33	deleterious	4,5	24,3	0,02	0,35	disease	0,87	disease	0,94	disease	0,77	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,31	0,8	45,97	9,16	P	0,64	P	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11454	11454	C	G	MI.17787	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	695	232	A	G	gCc/gGc	9,01	1	0	probably_damaging	1	deleterious	0	neutral	4,2	deleterious	-4,23	deleterious	-3,28	high_impact	3,69	damaging	0,47	neutral	0,44	deleterious	4	23,6	0,1	0,4	disease	0,8	disease	0,82	disease	0,62	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,53	0,59	0,8	45,97	9,16	P	0,62	P	0,79	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11454	11454	C	T	MI.17788	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	695	232	A	V	gCc/gTc	9,01	1	0	probably_damaging	1	deleterious	0,01	neutral	4,22	deleterious	-3,59	deleterious	-3,28	high_impact	4,59	damaging	0,4	neutral	0,3	deleterious	4,52	24,3	0,07	0,35	disease	0,54	disease	0,9	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,54	medium_impact	-0,92	high_impact	3,42	0,6	0,8	45,97	9,16	P	0,78	P	0,72	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11456	11456	G	C	MI.17789	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	697	233	A	P	Gca/Cca	-7,57	0	0	probably_damaging	0,99	deleterious	0	neutral	4,4	deleterious	-5,2	deleterious	-4,13	high_impact	3,64	neutral	0,65	damaging	0,11	deleterious	3,91	23,5	0,03	0,35	disease	0,84	disease	0,92	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-2,59	low_impact	-1,48	high_impact	2,48	0,54	0,8	46,41	9,37	N	0,28	N	0,96	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8523	8523	C	G	MI.1779	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	158	53	P	R	cCa/cGa	-0,1	0	0	benign	0,23	neutral	0,34	neutral	1,99	neutral	-0,21	neutral	0,05	low_impact	0,8	neutral	1	neutral	0,44	neutral	-0,2	1,12	0,38800886	0,85	neutral	0,21	neutral	0,22	neutral	0,36	neutral	0,11	8	neutral	0,59	deleterious	0,56	neutral	-6	neutral	0,23	medium_impact	-0,26	medium_impact	0,13	medium_impact	-0,41	0,62	0,85	NA	NA	N	0,48	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11456	11456	G	T	MI.17790	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	697	233	A	S	Gca/Tca	-7,57	0	0	possibly_damaging	0,9	neutral	0,1	neutral	4,52	neutral	-2,82	neutral	-2,47	medium_impact	2,19	neutral	0,72	damaging	0,16	deleterious	3,75	23,3	0,13	0,4	neutral	0,27	disease	0,86	disease	0,55	disease	0,7	4	neutral	0,96	neutral	0,1	NA	0	deleterious	0,77	low_impact	-1,61	medium_impact	-0,33	medium_impact	1,04	0,46	0,8	46,41	9,37	N	0,35	N	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11456	11456	G	A	MI.17791	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	697	233	A	T	Gca/Aca	-7,57	0	0	benign	0,42	deleterious	0	neutral	4,6	deleterious	-3,89	deleterious	-3,3	medium_impact	3,29	neutral	0,7	damaging	0,14	deleterious	4,2	23,9	0,06	0,35	neutral	0,22	disease	0,83	neutral	0,49	disease	0,7	4	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,76	medium_impact	-0,59	low_impact	-1,48	high_impact	2,13	0,7	0,85	46,41	9,37	N	0,37	N	0,82	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11457	11457	C	A	MI.17792	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	698	233	A	E	gCa/gAa	4,17	1	0	probably_damaging	0,98	deleterious	0	neutral	4,42	deleterious	-5,37	deleterious	-4,13	high_impact	3,98	neutral	0,68	damaging	0,13	deleterious	4,51	24,3	0,02	0,35	disease	0,8	disease	0,92	disease	0,7	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,31	low_impact	-1,48	high_impact	2,81	0,33	0,8	46,41	9,37	P	0,54	P	0,99	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11457	11457	C	G	MI.17793	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	698	233	A	G	gCa/gGa	4,17	1	0	probably_damaging	0,92	neutral	1	neutral	4,56	neutral	-0,55	deleterious	-3,3	low_impact	1,01	neutral	0,66	damaging	0,17	deleterious	3,99	23,6	0,17	0,45	disease	0,61	disease	0,5	neutral	0,32	neutral	0,47	1	neutral	0,92	deleterious	0,54	neutral	-2	deleterious	0,77	low_impact	-1,71	high_impact	1,88	medium_impact	-0,13	0,64	0,8	46,41	9,37	N	0,4	N	0,79	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11457	11457	C	T	MI.17794	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	698	233	A	V	gCa/gTa	4,17	1	0	possibly_damaging	0,9	deleterious	0	neutral	4,48	deleterious	-3,5	deleterious	-3,3	high_impact	3,98	neutral	0,64	damaging	0,11	deleterious	4,51	24,3	0,05	0,35	disease	0,72	disease	0,89	disease	0,58	disease	0,7	4	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,86	low_impact	-1,61	low_impact	-1,48	high_impact	2,81	0,53	0,8	46,41	9,37	P	0,61	P	0,72	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11459	11459	G	T	MI.17795	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	700	234	V	L	Gta/Tta	-11,71	0	0	benign	0,05	neutral	0,28	neutral	4,77	neutral	-1,1	neutral	-1,47	low_impact	1,58	neutral	0,71	neutral	0,59	deleterious	3,71	23,3	0,18	0,45	neutral	0,31	disease	0,79	neutral	0,37	disease	0,52	0	neutral	0,7	deleterious	0,62	neutral	-6	deleterious	0,75	medium_impact	0,48	medium_impact	-0,03	medium_impact	0,44	0,28	0,8	29,41	8,22	N	0,42	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11459	11459	G	C	MI.17796	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	700	234	V	L	Gta/Cta	-11,71	0	0	benign	0,05	neutral	0,28	neutral	4,77	neutral	-1,1	neutral	-1,47	low_impact	1,58	neutral	0,71	neutral	0,59	deleterious	3,6	23,2	0,18	0,45	neutral	0,31	disease	0,79	neutral	0,37	disease	0,52	0	neutral	0,7	deleterious	0,62	neutral	-6	deleterious	0,75	medium_impact	0,48	medium_impact	-0,03	medium_impact	0,44	0,28	0,8	29,41	8,22	N	0,41	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11459	11459	G	A	MI.17797	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	700	234	V	M	Gta/Ata	-11,71	0	0	benign	0,4	deleterious	0	neutral	4,56	deleterious	-3,56	neutral	-1,97	medium_impact	3,27	neutral	0,69	neutral	0,55	deleterious	3,74	23,3	0,12	0,4	disease	0,56	disease	0,85	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,78	medium_impact	-0,55	low_impact	-1,48	high_impact	2,11	0,56	0,8	29,41	8,22	N	0,36	N	0,56	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11460	11460	T	C	MI.17798	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	701	234	V	A	gTa/gCa	0,03	0	0	possibly_damaging	0,53	deleterious	0	neutral	4,63	neutral	-1,27	deleterious	-3,27	medium_impact	2,58	neutral	0,73	neutral	0,62	deleterious	3,55	23,1	0,09	0,35	neutral	0,17	disease	0,77	disease	0,55	disease	0,67	3	deleterious	1	neutral	0,24	deleterious	4	deleterious	0,71	medium_impact	-0,77	low_impact	-1,48	medium_impact	1,43	0,11	0,8	29,41	8,22	N	0,39	N	0,9	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11460	11460	T	G	MI.17799	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	701	234	V	G	gTa/gGa	0,03	0	0	probably_damaging	0,91	deleterious	0,04	neutral	4,52	deleterious	-3,28	deleterious	-5,73	medium_impact	2,85	neutral	0,71	neutral	0,54	deleterious	3,82	23,4	0,03	0,35	disease	0,69	disease	0,88	disease	0,6	disease	0,72	4	deleterious	0,99	neutral	0,07	deleterious	5	deleterious	0,82	low_impact	-1,66	medium_impact	-0,57	medium_impact	1,69	0,19	0,8	29,41	8,22	N	0,35	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8609	8609	C	G	MI.178	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	83	28	P	R	cCt/cGt	-0,57	0	0	possibly_damaging	0,77	neutral	0,06	neutral	4,4	neutral	0,62	neutral	-0,42	low_impact	1,15	neutral	0,87	neutral	0,41	neutral	1,74	14,64	0,29	0,65	neutral	0,31	disease	0,53	disease	0,54	disease	0,66	3	neutral	0,96	neutral	0,15	neutral	-3	deleterious	0,57	low_impact	-1,25	medium_impact	-0,38	medium_impact	-0,11	0,7	0,9	31,86	20,94	N	0,37	N	0,52	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8523	8523	C	T	MI.1780	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	158	53	P	L	cCa/cTa	-0,1	0	0	benign	0,11	neutral	0,68	neutral	2,02	neutral	0,49	neutral	0,38	neutral_impact	-1,52	neutral	0,99	neutral	0,88	deleterious	0,69	8,75	0,51005936	0,85	neutral	0,18	neutral	0,11	neutral	0,24	neutral	0,05	9	neutral	0,21	deleterious	0,79	neutral	-6	neutral	0,15	medium_impact	0,11	medium_impact	0,48	low_impact	-2,4	0,7	0,85	NA	NA	N	0,43	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11460	11460	T	A	MI.17800	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	701	234	V	E	gTa/gAa	0,03	0	0	probably_damaging	0,95	deleterious	0	neutral	4,51	deleterious	-5,01	deleterious	-4,92	high_impact	3,83	neutral	0,7	neutral	0,45	deleterious	4,81	24,8	0,02	0,35	disease	0,7	disease	0,94	disease	0,73	disease	0,87	7	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,88	low_impact	-1,92	low_impact	-1,48	high_impact	2,66	0,14	0,8	29,41	8,22	N	0,41	N	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11462	11462	C	G	MI.17801	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	703	235	L	V	Ctc/Gtc	-8,03	0	0	possibly_damaging	0,86	deleterious	0	neutral	4,25	neutral	-0,99	neutral	-2,49	medium_impact	3,13	neutral	0,64	neutral	0,49	deleterious	3,45	23	0,33	0,5	neutral	0,33	disease	0,75	disease	0,59	disease	0,66	3	deleterious	1	neutral	0,07	deleterious	4	deleterious	0,77	low_impact	-1,46	low_impact	-1,48	medium_impact	1,97	0,5	0,8	46,84	9,48	N	0,4	N	0,89	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11462	11462	C	T	MI.17802	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	703	235	L	F	Ctc/Ttc	-8,03	0	0	benign	0,29	deleterious	0	neutral	4,18	deleterious	-3,54	deleterious	-3,31	high_impact	3,72	damaging	0,6	neutral	0,5	deleterious	4,01	23,6	0,15	0,4	disease	0,71	disease	0,78	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,84	medium_impact	-0,35	low_impact	-1,48	high_impact	2,55	0,36	0,8	46,84	9,48	N	0,37	N	0,99	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11462	11462	C	A	MI.17803	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	703	235	L	I	Ctc/Atc	-8,03	0	0	possibly_damaging	0,86	neutral	0,05	neutral	4,24	neutral	-2,18	neutral	-1,66	medium_impact	3,37	neutral	0,67	neutral	0,58	deleterious	4,12	23,8	0,3	0,45	neutral	0,34	disease	0,77	disease	0,58	disease	0,66	3	neutral	0,97	neutral	0,1	NA	0	deleterious	0,76	low_impact	-1,46	medium_impact	-0,52	high_impact	2,21	0,52	0,8	46,84	9,48	N	0,48	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11463	11463	T	C	MI.17804	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	704	235	L	P	cTc/cCc	0,26	0,01	0	probably_damaging	0,99	deleterious	0	neutral	4,21	deleterious	-4,85	deleterious	-5,8	high_impact	3,83	damaging	0,59	neutral	0,48	deleterious	3,98	23,6	0,01	0,35	disease	0,86	disease	0,87	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,59	low_impact	-1,48	high_impact	2,66	0,24	0,8	46,84	9,48	N	0,35	N	0,98	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11463	11463	T	G	MI.17805	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	704	235	L	R	cTc/cGc	0,26	0,01	0	probably_damaging	0,99	deleterious	0	neutral	4,16	deleterious	-4,75	deleterious	-4,97	high_impact	4,52	damaging	0,59	neutral	0,39	deleterious	4,19	23,8	0,01	0,35	disease	0,82	disease	0,92	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-2,59	low_impact	-1,48	high_impact	3,35	0,17	0,8	46,84	9,48	N	0,47	N	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11463	11463	T	A	MI.17806	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	704	235	L	H	cTc/cAc	0,26	0,01	0	probably_damaging	0,99	deleterious	0	neutral	4,15	deleterious	-4,79	deleterious	-5,8	high_impact	4,52	neutral	0,63	neutral	0,41	deleterious	4,35	24,1	0,03	0,35	disease	0,87	disease	0,84	disease	0,67	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,59	low_impact	-1,48	high_impact	3,35	0,26	0,8	46,84	9,48	N	0,43	N	0,96	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11465	11465	T	G	MI.17807	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	706	236	L	V	Tta/Gta	-3,42	0	0	probably_damaging	1	deleterious	0	neutral	4,79	neutral	0,63	deleterious	-2,51	high_impact	4,05	damaging	0,36	neutral	0,53	deleterious	3,42	23	0,34	0,5	disease	0,62	disease	0,75	disease	0,58	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,88	0,56	0,8	47,06	9,26	P	0,65	P	0,89	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11465	11465	T	A	MI.17808	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	706	236	L	M	Tta/Ata	-3,42	0	0	probably_damaging	1	deleterious	0,04	neutral	4,36	deleterious	-3,43	neutral	-1,68	high_impact	3,7	damaging	0,4	neutral	0,63	deleterious	3,59	23,2	0,32	0,5	neutral	0,28	disease	0,73	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,72	low_impact	-3,54	medium_impact	-0,57	high_impact	2,53	0,52	0,8	47,06	9,26	P	0,58	P	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11466	11466	T	G	MI.17809	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	707	236	L	W	tTa/tGa	0,49	0,06	0	probably_damaging	1	deleterious	0	neutral	4,34	deleterious	-6,05	deleterious	-5,03	high_impact	4,25	damaging	0,41	neutral	0,47	deleterious	3,76	23,3	0,04	0,35	disease	0,93	disease	0,81	disease	0,61	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,08	0,21	0,8	47,06	9,26	P	0,59	P	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8523	8523	C	A	MI.1781	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	158	53	P	Q	cCa/cAa	-0,1	0	0	benign	0,29	neutral	0,29	neutral	2,01	neutral	0,27	neutral	0,29	neutral_impact	0,26	neutral	1	neutral	0,61	deleterious	0,37	6,37	0,34926686	0,85	neutral	0,2	neutral	0,23	neutral	0,31	neutral	0,14	7	neutral	0,65	deleterious	0,5	neutral	-6	neutral	0,19	medium_impact	-0,39	medium_impact	0,07	medium_impact	-0,88	0,55	0,85	NA	NA	N	0,49	N	0,42	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11466	11466	T	C	MI.17810	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	707	236	L	S	tTa/tCa	0,49	0,06	0	probably_damaging	1	deleterious	0	neutral	4,36	deleterious	-3,63	deleterious	-5,03	high_impact	3,7	damaging	0,38	neutral	0,6	deleterious	3,78	23,4	0,03	0,35	disease	0,74	disease	0,83	disease	0,6	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,53	0,19	0,8	47,06	9,26	P	0,63	P	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11467	11467	A	C	MI.17811	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	708	236	L	F	ttA/ttC	7,4	0,96	0,26	probably_damaging	1	deleterious	0	neutral	4,36	deleterious	-3,58	deleterious	-3,35	high_impact	4,6	damaging	0,39	neutral	0,49	deleterious	3,49	23,1	0,15	0,4	disease	0,78	disease	0,76	disease	0,59	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,43	0,43	0,8	47,06	9,26	P	0,77	P	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11467	11467	A	T	MI.17812	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	708	236	L	F	ttA/ttT	7,4	0,96	0,26	probably_damaging	1	deleterious	0	neutral	4,36	deleterious	-3,58	deleterious	-3,35	high_impact	4,6	damaging	0,39	neutral	0,49	deleterious	3,65	23,2	0,15	0,4	disease	0,78	disease	0,76	disease	0,59	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,43	0,43	0,8	47,06	9,26	P	0,77	P	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11468	11468	A	C	MI.17813	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	709	237	K	Q	Aaa/Caa	-2,5	0	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-4,28	deleterious	-3,28	high_impact	4,24	neutral	0,6	damaging	0,14	deleterious	3,46	23	0,11	0,4	disease	0,52	disease	0,8	disease	0,68	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,07	0,33	0,8	46,62	9,35	N	0,4	N	0,86	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11468	11468	A	G	MI.17814	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	709	237	K	E	Aaa/Gaa	-2,5	0	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-3,83	deleterious	-3,28	high_impact	4,59	damaging	0,6	damaging	0,16	deleterious	4,01	23,6	0,08	0,35	neutral	0,34	disease	0,86	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,36	0,8	46,62	9,35	N	0,49	N	0,87	polymorphism	1	0,32	rs878972941	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11469	11469	A	C	MI.17815	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	710	237	K	T	aAa/aCa	6,7	1	0	probably_damaging	1	deleterious	0	neutral	4,59	neutral	-2,55	deleterious	-4,92	high_impact	4,24	neutral	0,66	damaging	0,12	deleterious	3,6	23,2	0,07	0,35	disease	0,55	disease	0,81	disease	0,67	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,07	0,23	0,8	46,62	9,35	P	0,61	P	0,77	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11469	11469	A	T	MI.17816	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	710	237	K	M	aAa/aTa	6,7	1	0	probably_damaging	1	deleterious	0	neutral	4,46	deleterious	-6,1	deleterious	-4,99	high_impact	4,59	neutral	0,63	damaging	0,13	deleterious	3,83	23,4	0,07	0,35	neutral	0,47	disease	0,86	disease	0,68	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,28	0,8	46,62	9,35	P	0,56	P	0,42	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11470	11470	A	T	MI.17817	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	711	237	K	N	aaA/aaT	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,47	deleterious	-3,5	deleterious	-3,9	medium_impact	3,44	damaging	0,59	damaging	0,16	deleterious	3,8	23,4	0,17	0,45	disease	0,68	disease	0,8	disease	0,64	disease	0,66	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,28	0,24	0,8	46,62	9,35	P	0,57	P	0,72	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11470	11470	A	C	MI.17818	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	711	237	K	N	aaA/aaC	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,47	deleterious	-3,5	deleterious	-3,9	medium_impact	3,44	damaging	0,59	damaging	0,16	deleterious	3,75	23,3	0,17	0,45	disease	0,68	disease	0,8	disease	0,64	disease	0,66	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,28	0,24	0,8	46,62	9,35	P	0,56	P	0,72	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11471	11471	C	G	MI.17819	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	712	238	L	V	Cta/Gta	0,95	0,97	0	possibly_damaging	0,9	deleterious	0	neutral	4,48	neutral	0,66	deleterious	-2,56	medium_impact	3,41	damaging	0,54	damaging	0,1	deleterious	3,43	23	0,36	0,5	disease	0,56	disease	0,73	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,05	deleterious	4	deleterious	0,8	low_impact	-1,61	low_impact	-1,48	high_impact	2,25	0,57	0,8	46,62	9,3	N	0,43	N	0,89	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8525	8525	A	C	MI.1782	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	160	54	K	Q	Aaa/Caa	0,13	0	0	probably_damaging	0,99	neutral	0,45	neutral	1,73	deleterious	-5,01	deleterious	-3,82	high_impact	3,52	neutral	0,98	neutral	0,44	deleterious	3,42	23	0,44021289	0,85	disease	0,66	disease	0,66	disease	0,69	disease	0,64	3	deleterious	0,99	neutral	0,23	deleterious	2	deleterious	0,82	low_impact	-2,65	medium_impact	0,24	medium_impact	1,92	0,54	0,85	16,18	8,12	N	0,43	N	0,8	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11471	11471	C	A	MI.17820	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	712	238	L	M	Cta/Ata	0,95	0,97	0	possibly_damaging	0,76	deleterious	0,04	neutral	4,44	neutral	-0,36	neutral	-1,7	medium_impact	2,44	damaging	0,57	damaging	0,24	deleterious	3,95	23,6	0,38	0,5	disease	0,68	disease	0,68	neutral	0,5	neutral	0,49	0	neutral	0,97	neutral	0,14	deleterious	4	deleterious	0,78	low_impact	-1,19	medium_impact	-0,57	medium_impact	1,29	0,5	0,8	46,62	9,3	N	0,48	N	0,9	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11472	11472	T	G	MI.17821	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	713	238	L	R	cTa/cGa	0,26	0,95	0	probably_damaging	0,98	deleterious	0	neutral	4,37	deleterious	-3,75	deleterious	-5,12	high_impact	4,5	damaging	0,56	damaging	0,08	deleterious	4,26	23,9	0,02	0,35	disease	0,83	disease	0,91	disease	0,75	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,91	low_impact	-2,31	low_impact	-1,48	high_impact	3,33	0,13	0,8	46,62	9,3	P	0,54	P	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11472	11472	T	A	MI.17822	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	713	238	L	Q	cTa/cAa	0,26	0,95	0	probably_damaging	0,99	deleterious	0	neutral	4,37	deleterious	-3,93	deleterious	-5,12	high_impact	4,16	damaging	0,53	damaging	0,1	deleterious	4,42	24,2	0,03	0,35	disease	0,84	disease	0,84	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,59	low_impact	-1,48	high_impact	2,99	0,22	0,8	46,62	9,3	N	0,42	N	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11472	11472	T	C	MI.17823	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	713	238	L	P	cTa/cCa	0,26	0,95	0	probably_damaging	1	deleterious	0	neutral	4,36	deleterious	-4,23	deleterious	-5,98	high_impact	4,5	damaging	0,51	damaging	0,08	deleterious	4	23,6	0,02	0,35	disease	0,87	disease	0,85	disease	0,75	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,16	0,8	46,62	9,3	P	0,51	P	0,98	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11474	11474	G	C	MI.17824	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	715	239	G	R	Ggc/Cgc	-1,35	0,01	0	probably_damaging	1	deleterious	0	neutral	4,16	deleterious	-6,2	deleterious	-6,86	high_impact	3,92	damaging	0,48	damaging	0,25	deleterious	3,89	23,5	0,02	0,35	disease	0,64	disease	0,92	disease	0,82	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	2,75	0,48	0,8	46,84	9,18	N	0,49	N	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11474	11474	G	T	MI.17825	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	715	239	G	C	Ggc/Tgc	-1,35	0,01	0	probably_damaging	1	deleterious	0	neutral	4,14	deleterious	-7,84	deleterious	-7,72	high_impact	4,62	damaging	0,48	damaging	0,24	deleterious	4,14	23,8	0,02	0,35	disease	0,91	disease	0,91	disease	0,75	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,25	0,8	46,84	9,18	N	0,48	N	0,98	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11474	11474	G	A	MI.17826	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	715	239	G	S	Ggc/Agc	-1,35	0,01	0	probably_damaging	1	deleterious	0	neutral	4,21	deleterious	-4,52	deleterious	-5,14	high_impact	3,58	damaging	0,5	neutral	0,4	deleterious	4,18	23,8	0,03	0,35	disease	0,57	disease	0,86	disease	0,71	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	2,42	0,66	0,8	46,84	9,18	N	0,41	N	0,97	polymorphism	1	0,2	rs28371977	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11475	11475	G	T	MI.17827	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	716	239	G	V	gGc/gTc	9,01	1	0,01	probably_damaging	1	deleterious	0	neutral	4,17	deleterious	-5,67	deleterious	-7,72	high_impact	4,07	damaging	0,47	neutral	0,33	deleterious	3,76	23,3	0,02	0,35	disease	0,73	disease	0,92	disease	0,74	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	2,9	0,2	0,8	46,84	9,18	P	0,61	P	0,98	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11475	11475	G	A	MI.17828	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	716	239	G	D	gGc/gAc	9,01	1	0,01	probably_damaging	1	deleterious	0	neutral	4,16	deleterious	-6,72	deleterious	-6	high_impact	4,62	damaging	0,47	neutral	0,3	deleterious	3,86	23,5	0,02	0,35	disease	0,59	disease	0,92	disease	0,81	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,15	0,8	46,84	9,18	P	0,67	P	0,99	polymorphism	1	0,44	.	.	.	.	.	pituitary oncocytoma	.	.	.	.	.	.	.	.	.
chrM	11475	11475	G	C	MI.17829	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	716	239	G	A	gGc/gCc	9,01	1	0,01	probably_damaging	1	deleterious	0	neutral	4,27	neutral	-2,32	deleterious	-5,14	medium_impact	3,23	damaging	0,54	neutral	0,43	deleterious	3,14	22,6	0,07	0,35	neutral	0,3	disease	0,79	disease	0,7	disease	0,69	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	2,07	0,32	0,8	46,84	9,18	P	0,54	P	0,76	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8525	8525	A	G	MI.1783	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	160	54	K	E	Aaa/Gaa	0,13	0	0	probably_damaging	0,97	neutral	0,53	neutral	1,72	deleterious	-4,91	deleterious	-3,8	high_impact	3,52	neutral	0,99	neutral	0,59	deleterious	2,96	22,1	0,20859529	0,85	disease	0,66	disease	0,53	disease	0,68	neutral	0,37	3	neutral	0,97	neutral	0,28	deleterious	2	deleterious	0,83	low_impact	-2,19	medium_impact	0,32	medium_impact	1,92	0,48	0,85	16,18	8,12	N	0,41	N	0,86	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11477	11477	G	A	MI.17830	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	718	240	G	S	Ggc/Agc	-13,55	0	0	probably_damaging	1	neutral	0,1	neutral	4,53	neutral	-1,76	deleterious	-4,96	low_impact	1,9	neutral	0,61	neutral	0,45	deleterious	4,16	23,8	0,07	0,35	neutral	0,33	disease	0,85	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,78	low_impact	-3,54	medium_impact	-0,33	medium_impact	0,75	0,71	0,85	22,22	8,72	N	0,28	N	0,51	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11477	11477	G	C	MI.17831	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	718	240	G	R	Ggc/Cgc	-13,55	0	0	probably_damaging	1	deleterious	0	neutral	4,51	neutral	-2,89	deleterious	-6,74	high_impact	4,38	neutral	0,68	damaging	0,11	deleterious	4	23,6	0,03	0,35	disease	0,56	disease	0,93	disease	0,77	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	3,21	0,28	0,8	22,22	8,72	N	0,47	N	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11477	11477	G	T	MI.17832	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	718	240	G	C	Ggc/Tgc	-13,55	0	0	probably_damaging	1	deleterious	0,02	neutral	4,51	deleterious	-3,34	deleterious	-7,58	medium_impact	3,23	neutral	0,66	damaging	0,11	deleterious	4,19	23,9	0,04	0,35	disease	0,72	disease	0,91	disease	0,59	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,85	low_impact	-3,54	medium_impact	-0,75	high_impact	2,07	0,23	0,8	22,22	8,72	N	0,29	N	0,89	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11478	11478	G	A	MI.17833	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	719	240	G	D	gGc/gAc	5,09	1	0	probably_damaging	1	deleterious	0	neutral	4,5	deleterious	-4,21	deleterious	-5,88	high_impact	3,68	neutral	0,71	damaging	0,12	deleterious	3,82	23,4	0,02	0,35	neutral	0,49	disease	0,93	disease	0,75	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	2,52	0,2	0,8	22,22	8,72	P	0,55	P	0,93	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11478	11478	G	T	MI.17834	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	719	240	G	V	gGc/gTc	5,09	1	0	probably_damaging	1	deleterious	0,02	neutral	4,69	neutral	1,79	deleterious	-7,6	medium_impact	3,02	neutral	0,65	damaging	0,12	deleterious	3,81	23,4	0,04	0,35	neutral	0,29	disease	0,92	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,81	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,86	0,24	0,8	22,22	8,72	N	0,49	N	0,98	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11478	11478	G	C	MI.17835	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	719	240	G	A	gGc/gCc	5,09	1	0	probably_damaging	1	deleterious	0,03	neutral	4,58	neutral	0,82	deleterious	-5,02	medium_impact	2,55	neutral	0,69	damaging	0,17	deleterious	3,15	22,6	0,12	0,4	neutral	0,4	disease	0,79	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,4	0,3	0,8	22,22	8,72	P	0,52	P	0,72	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11480	11480	T	A	MI.17836	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	721	241	Y	N	Tat/Aat	-10,79	0	0	probably_damaging	1	deleterious	0	neutral	4,31	deleterious	-6,38	deleterious	-7,75	high_impact	4,59	damaging	0,56	neutral	0,41	deleterious	4,11	23,7	0,05	0,35	neutral	0,47	disease	0,88	disease	0,76	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,32	0,8	46,62	9,38	N	0,51	P	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11480	11480	T	C	MI.17837	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	721	241	Y	H	Tat/Cat	-10,79	0	0	probably_damaging	1	deleterious	0	neutral	4,3	deleterious	-6,48	deleterious	-4,31	high_impact	4,04	damaging	0,56	neutral	0,35	deleterious	3,64	23,2	0,11	0,4	disease	0,7	disease	0,86	disease	0,83	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	2,87	0,32	0,8	46,62	9,38	N	0,42	N	0,97	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11480	11480	T	G	MI.17838	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	721	241	Y	D	Tat/Gat	-10,79	0	0	probably_damaging	1	deleterious	0	neutral	4,3	deleterious	-7,3	deleterious	-8,62	high_impact	4,59	neutral	0,69	neutral	0,37	deleterious	4,04	23,7	0,03	0,35	neutral	0,35	disease	0,92	disease	0,83	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,23	0,8	46,62	9,38	P	0,53	P	0,99	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11481	11481	A	G	MI.17839	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	722	241	Y	C	tAt/tGt	7,4	1	0	probably_damaging	1	deleterious	0,01	neutral	4,31	deleterious	-6,34	deleterious	-7,76	high_impact	4,59	damaging	0,54	neutral	0,29	deleterious	3,6	23,2	0,05	0,35	disease	0,9	disease	0,89	disease	0,8	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,54	medium_impact	-0,92	high_impact	3,42	0,21	0,8	46,62	9,38	P	0,63	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8526	8526	A	T	MI.1784	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	161	54	K	M	aAa/aTa	3,83	0,99	0	probably_damaging	1	neutral	0,24	neutral	1,68	deleterious	-7,2	deleterious	-5,75	medium_impact	2,98	neutral	1	neutral	0,5	deleterious	3,88	23,5	0,18776742	0,85	disease	0,89	disease	0,52	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,01	medium_impact	1,46	0,4	0,85	16,18	8,12	P	0,64	P	0,69	disease_causing	0,83	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11481	11481	A	T	MI.17840	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	722	241	Y	F	tAt/tTt	7,4	1	0	probably_damaging	1	neutral	0,08	neutral	4,44	neutral	-1,17	deleterious	-3,45	medium_impact	2,82	damaging	0,59	neutral	0,42	deleterious	3,54	23,1	0,16	0,45	disease	0,82	disease	0,84	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	-0,39	medium_impact	1,66	0,57	0,8	46,62	9,38	P	0,63	P	0,79	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11481	11481	A	C	MI.17841	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	722	241	Y	S	tAt/tCt	7,4	1	0	probably_damaging	1	deleterious	0	neutral	4,37	deleterious	-5,05	deleterious	-7,75	high_impact	4,59	neutral	0,6	neutral	0,49	deleterious	3,87	23,5	0,05	0,35	neutral	0,38	disease	0,88	disease	0,76	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,33	0,8	46,62	9,38	P	0,58	P	0,95	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11483	11483	G	T	MI.17842	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	724	242	G	C	Ggt/Tgt	-6,19	0	0	probably_damaging	1	deleterious	0	neutral	4,44	deleterious	-4,35	deleterious	-7,78	high_impact	4,63	damaging	0,49	damaging	0,22	deleterious	4,17	23,8	0,04	0,35	disease	0,81	disease	0,93	disease	0,71	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,2	0,8	45,97	9,19	N	0,47	N	0,98	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11483	11483	G	C	MI.17843	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	724	242	G	R	Ggt/Cgt	-6,19	0	0	possibly_damaging	0,58	deleterious	0	neutral	4,45	deleterious	-4,87	deleterious	-6,92	high_impact	4,29	damaging	0,43	damaging	0,23	deleterious	4	23,6	0,04	0,35	disease	0,73	disease	0,94	disease	0,8	disease	0,83	7	deleterious	1	neutral	0,21	deleterious	5	deleterious	0,9	medium_impact	-0,85	low_impact	-1,48	high_impact	3,12	0,42	0,8	45,97	9,19	P	0,56	P	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11483	11483	G	A	MI.17844	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	724	242	G	S	Ggt/Agt	-6,19	0	0	probably_damaging	0,98	deleterious	0	neutral	4,47	deleterious	-3,2	deleterious	-5,19	high_impact	4,29	damaging	0,52	neutral	0,33	deleterious	4,28	24	0,06	0,35	neutral	0,47	disease	0,88	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,31	low_impact	-1,48	high_impact	3,12	0,57	0,8	45,97	9,19	N	0,44	N	0,97	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11484	11484	G	C	MI.17845	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	725	242	G	A	gGt/gCt	6,01	1	0	probably_damaging	0,94	deleterious	0	neutral	4,5	neutral	-0,56	deleterious	-5,19	medium_impact	3,43	damaging	0,55	neutral	0,39	deleterious	3,09	22,5	0,09	0,35	disease	0,53	disease	0,83	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,83	low_impact	-1,84	low_impact	-1,48	high_impact	2,27	0,36	0,8	45,97	9,19	P	0,59	P	0,76	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11484	11484	G	T	MI.17846	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	725	242	G	V	gGt/gTt	6,01	1	0	probably_damaging	0,99	deleterious	0	neutral	4,57	neutral	-1,9	deleterious	-7,78	high_impact	4,29	damaging	0,49	neutral	0,29	deleterious	3,78	23,4	0,04	0,35	neutral	0,47	disease	0,93	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,59	low_impact	-1,48	high_impact	3,12	0,25	0,8	45,97	9,19	P	0,65	P	0,98	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11484	11484	G	A	MI.17847	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	725	242	G	D	gGt/gAt	6,01	1	0	probably_damaging	0,99	deleterious	0	neutral	4,44	deleterious	-6,02	deleterious	-6,05	high_impact	4,63	damaging	0,54	damaging	0,28	deleterious	3,8	23,4	0,03	0,35	disease	0,81	disease	0,93	disease	0,79	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,59	low_impact	-1,48	high_impact	3,45	0,28	0,8	45,97	9,19	P	0,59	P	0,99	polymorphism	1	0,44	.	.	.	.	.	.	COSM1155510	.	.	.	.	.	.	.	.
chrM	11486	11486	A	G	MI.17848	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	727	243	M	V	Ata/Gta	-14,94	0	0	possibly_damaging	0,53	neutral	0,22	neutral	4,64	neutral	-0,01	neutral	-2,5	low_impact	1,4	neutral	0,72	neutral	0,59	deleterious	2,72	20,9	0,12	0,4	disease	0,75	disease	0,77	disease	0,62	disease	0,66	3	neutral	0,77	neutral	0,35	neutral	-3	deleterious	0,71	medium_impact	-0,77	medium_impact	-0,11	medium_impact	0,26	0,5	0,8	16,99	22,09	N	0,32	N	0,82	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11486	11486	A	T	MI.17849	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	727	243	M	L	Ata/Tta	-14,94	0	0	benign	0,03	neutral	1	neutral	5,27	neutral	2,7	neutral	-1,92	neutral_impact	0,34	neutral	0,73	neutral	0,59	deleterious	3,31	22,9	0,16	0,45	disease	0,57	disease	0,62	neutral	0,49	neutral	0,47	1	neutral	0,03	deleterious	0,99	neutral	-6	deleterious	0,61	medium_impact	0,7	high_impact	1,88	medium_impact	-0,79	0,48	0,8	16,99	22,09	N	0,28	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8526	8526	A	C	MI.1785	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	161	54	K	T	aAa/aCa	3,83	0,99	0	probably_damaging	0,98	neutral	0,55	neutral	1,71	deleterious	-5,6	deleterious	-5,74	medium_impact	2,42	neutral	1	neutral	0,73	deleterious	3,63	23,2	0,30462661	0,85	disease	0,75	disease	0,66	disease	0,65	disease	0,63	3	deleterious	0,98	neutral	0,29	deleterious	1	deleterious	0,85	low_impact	-2,36	medium_impact	0,34	medium_impact	0,98	0,33	0,85	16,18	8,12	P	0,56	P	0,81	disease_causing	0,68	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11486	11486	A	C	MI.17850	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	727	243	M	L	Ata/Cta	-14,94	0	0	benign	0,03	neutral	1	neutral	5,27	neutral	2,7	neutral	-1,92	neutral_impact	0,34	neutral	0,73	neutral	0,59	deleterious	3,21	22,7	0,16	0,45	disease	0,57	disease	0,62	neutral	0,49	neutral	0,47	1	neutral	0,03	deleterious	0,99	neutral	-6	deleterious	0,61	medium_impact	0,7	high_impact	1,88	medium_impact	-0,79	0,48	0,8	16,99	22,09	N	0,28	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11487	11487	T	A	MI.17851	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	728	243	M	K	aTa/aAa	5,55	1	0	possibly_damaging	0,89	deleterious	0	neutral	4,5	deleterious	-3,86	deleterious	-4,86	medium_impact	3,48	neutral	0,7	neutral	0,43	deleterious	3,88	23,5	0,02	0,35	disease	0,82	disease	0,91	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,06	deleterious	4	deleterious	0,85	low_impact	-1,57	low_impact	-1,48	high_impact	2,32	0,35	0,8	16,99	22,09	P	0,61	P	0,95	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11487	11487	T	C	MI.17852	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	728	243	M	T	aTa/aCa	5,55	1	0	possibly_damaging	0,78	deleterious	0	neutral	4,52	neutral	-2,45	deleterious	-4,54	medium_impact	3,14	neutral	0,7	neutral	0,53	deleterious	2,94	22	0,06	0,35	disease	0,76	disease	0,78	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,11	deleterious	4	deleterious	0,82	low_impact	-1,23	low_impact	-1,48	medium_impact	1,98	0,28	0,8	16,99	22,09	P	0,61	P	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11488	11488	A	C	MI.17853	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	729	243	M	I	atA/atC	7,4	1	0	benign	0,4	neutral	0,75	neutral	4,73	neutral	0,66	neutral	-2,33	neutral_impact	0,08	neutral	0,7	neutral	0,68	deleterious	2,03	16,43	0,14	0,4	disease	0,62	neutral	0,26	neutral	0,4	disease	0,56	1	neutral	0,29	deleterious	0,68	neutral	-6	deleterious	0,67	medium_impact	-0,55	medium_impact	0,47	low_impact	-1,05	0,56	0,8	16,99	22,09	P	0,56	P	0,51	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11488	11488	A	T	MI.17854	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	729	243	M	I	atA/atT	7,4	1	0	benign	0,4	neutral	0,75	neutral	4,73	neutral	0,66	neutral	-2,33	neutral_impact	0,08	neutral	0,7	neutral	0,68	deleterious	2,1	16,86	0,14	0,4	disease	0,62	neutral	0,26	neutral	0,4	disease	0,56	1	neutral	0,29	deleterious	0,68	neutral	-6	deleterious	0,67	medium_impact	-0,55	medium_impact	0,47	low_impact	-1,05	0,56	0,8	16,99	22,09	P	0,56	P	0,51	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11489	11489	A	G	MI.17855	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	730	244	M	V	Ata/Gta	-1,81	0	0	benign	0,17	deleterious	0,04	neutral	4,71	neutral	1,17	neutral	-2,47	low_impact	1,3	neutral	0,78	neutral	0,65	deleterious	2,76	21,2	0,15	0,4	disease	0,69	disease	0,72	neutral	0,46	neutral	0,41	2	neutral	0,95	neutral	0,44	neutral	-2	deleterious	0,66	medium_impact	-0,07	medium_impact	-0,57	medium_impact	0,16	0,37	0,8	8,93	21,34	N	0,3	N	0,64	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11489	11489	A	C	MI.17856	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	730	244	M	L	Ata/Cta	-1,81	0	0	benign	0,01	neutral	0,96	neutral	4,74	neutral	2,43	neutral	-1,53	neutral_impact	-0,12	neutral	0,8	neutral	0,98	deleterious	1,94	15,86	0,16	0,45	disease	0,51	disease	0,58	neutral	0,38	neutral	0,37	3	neutral	0,01	deleterious	0,98	neutral	-6	deleterious	0,56	medium_impact	1,16	medium_impact	0,98	low_impact	-1,25	0,33	0,8	8,93	21,34	N	0,28	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11489	11489	A	T	MI.17857	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	730	244	M	L	Ata/Tta	-1,81	0	0	benign	0,01	neutral	0,96	neutral	4,74	neutral	2,43	neutral	-1,53	neutral_impact	-0,12	neutral	0,8	neutral	0,98	deleterious	2,01	16,3	0,16	0,45	disease	0,51	disease	0,58	neutral	0,38	neutral	0,37	3	neutral	0,01	deleterious	0,98	neutral	-6	deleterious	0,56	medium_impact	1,16	medium_impact	0,98	low_impact	-1,25	0,33	0,8	8,93	21,34	N	0,28	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11490	11490	T	C	MI.17858	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	731	244	M	T	aTa/aCa	0,72	0,08	0	possibly_damaging	0,56	deleterious	0,02	neutral	4,61	neutral	-0,78	deleterious	-4,36	medium_impact	2,54	neutral	0,67	neutral	0,52	deleterious	3,04	22,4	0,06	0,35	disease	0,55	disease	0,73	disease	0,62	disease	0,67	3	neutral	0,98	neutral	0,23	deleterious	4	deleterious	0,74	medium_impact	-0,82	medium_impact	-0,75	medium_impact	1,39	0,23	0,8	8,93	21,34	N	0,37	N	0,75	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11490	11490	T	A	MI.17859	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	731	244	M	K	aTa/aAa	0,72	0,08	0	possibly_damaging	0,81	deleterious	0	neutral	4,52	neutral	-2,46	deleterious	-4,68	medium_impact	3	neutral	0,68	neutral	0,43	deleterious	4,15	23,8	0,02	0,35	neutral	0,32	disease	0,89	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	4	deleterious	0,75	low_impact	-1,31	low_impact	-1,48	medium_impact	1,84	0,28	0,8	8,93	21,34	N	0,43	N	0,9	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8527	8527	A	T	MI.1786	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	162	54	K	N	aaA/aaT	2,21	1	0	probably_damaging	0,99	neutral	0,44	neutral	1,69	deleterious	-5,5	deleterious	-4,62	high_impact	3,52	neutral	0,98	neutral	0,45	deleterious	3,94	23,6	0,37793802	0,85	disease	0,73	disease	0,66	disease	0,68	disease	0,63	3	deleterious	0,99	neutral	0,23	deleterious	2	deleterious	0,84	low_impact	-2,65	medium_impact	0,23	medium_impact	1,92	0,38	0,85	16,18	8,12	P	0,56	P	0,71	disease_causing	0,94	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11491	11491	A	T	MI.17860	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	732	244	M	I	atA/atT	5,78	0,89	0	benign	0,03	neutral	0,7	neutral	4,65	neutral	1,76	neutral	-2,28	neutral_impact	-0,1	neutral	0,65	neutral	0,95	deleterious	2,3	18,17	0,17	0,45	disease	0,66	neutral	0,25	neutral	0,34	disease	0,57	1	neutral	0,25	deleterious	0,84	neutral	-6	deleterious	0,65	medium_impact	0,7	medium_impact	0,41	low_impact	-1,23	0,43	0,8	8,93	21,34	N	0,5	N	0,34	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11491	11491	A	C	MI.17861	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	732	244	M	I	atA/atC	5,78	0,89	0	benign	0,03	neutral	0,7	neutral	4,65	neutral	1,76	neutral	-2,28	neutral_impact	-0,1	neutral	0,65	neutral	0,95	deleterious	2,24	17,75	0,17	0,45	disease	0,66	neutral	0,25	neutral	0,34	disease	0,57	1	neutral	0,25	deleterious	0,84	neutral	-6	deleterious	0,65	medium_impact	0,7	medium_impact	0,41	low_impact	-1,23	0,43	0,8	8,93	21,34	N	0,49	N	0,34	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11492	11492	C	G	MI.17862	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	733	245	R	G	Cgc/Ggc	-0,66	0,04	0	possibly_damaging	0,72	deleterious	0	neutral	4,19	deleterious	-5,95	deleterious	-6,06	high_impact	4,25	damaging	0,46	neutral	0,4	deleterious	4,24	23,9	0,02	0,35	neutral	0,41	disease	0,73	disease	0,8	disease	0,7	4	deleterious	1	neutral	0,14	deleterious	5	deleterious	0,74	low_impact	-1,1	low_impact	-1,48	high_impact	3,08	0,14	0,8	47,06	9,4	P	0,53	P	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11492	11492	C	T	MI.17863	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	733	245	R	C	Cgc/Tgc	-0,66	0,04	0	probably_damaging	0,98	deleterious	0	neutral	4,16	deleterious	-8,01	deleterious	-6,92	high_impact	4,05	damaging	0,46	damaging	0,21	deleterious	5,04	25,2	0,04	0,35	disease	0,67	disease	0,84	disease	0,83	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,31	low_impact	-1,48	high_impact	2,88	0,49	0,8	47,06	9,4	N	0,51	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11492	11492	C	A	MI.17864	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	733	245	R	S	Cgc/Agc	-0,66	0,04	0	possibly_damaging	0,76	deleterious	0	neutral	4,28	deleterious	-4,91	deleterious	-5,2	high_impact	4,25	damaging	0,49	neutral	0,43	deleterious	4,6	24,4	0,03	0,35	neutral	0,42	disease	0,81	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,12	deleterious	5	deleterious	0,76	low_impact	-1,19	low_impact	-1,48	high_impact	3,08	0,2	0,8	47,06	9,4	P	0,56	P	0,81	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11493	11493	G	C	MI.17865	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	734	245	R	P	cGc/cCc	1,41	0,68	0	probably_damaging	0,95	deleterious	0	neutral	4,18	deleterious	-6,59	deleterious	-6,06	high_impact	4,25	damaging	0,45	neutral	0,29	deleterious	4,3	24	0,02	0,35	disease	0,73	disease	0,87	disease	0,87	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,84	low_impact	-1,92	low_impact	-1,48	high_impact	3,08	0,11	0,8	47,06	9,4	P	0,6	P	0,99	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11493	11493	G	T	MI.17866	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	734	245	R	L	cGc/cTc	1,41	0,68	0	possibly_damaging	0,64	deleterious	0,01	neutral	4,2	deleterious	-4,72	deleterious	-6,06	high_impact	3,63	damaging	0,47	neutral	0,34	deleterious	4,36	24,1	0,02	0,35	disease	0,73	disease	0,91	disease	0,79	disease	0,75	5	deleterious	0,99	neutral	0,19	deleterious	5	deleterious	0,83	medium_impact	-0,95	medium_impact	-0,92	high_impact	2,47	0,07	0,8	47,06	9,4	P	0,53	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11493	11493	G	A	MI.17867	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	734	245	R	H	cGc/cAc	1,41	0,68	0	probably_damaging	0,95	deleterious	0,01	neutral	4,21	deleterious	-6,36	deleterious	-4,33	high_impact	4,25	damaging	0,44	damaging	0,21	deleterious	4,57	24,4	0,06	0,35	neutral	0,42	disease	0,81	disease	0,82	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,78	low_impact	-1,92	medium_impact	-0,92	high_impact	3,08	0,67	0,85	47,06	9,4	P	0,64	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11495	11495	C	G	MI.17868	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	736	246	L	V	Ctc/Gtc	-2,5	0	0	benign	0,4	neutral	0,84	neutral	4,46	neutral	-0,25	neutral	0,4	neutral_impact	0,45	neutral	0,75	neutral	0,97	deleterious	2,27	17,97	0,28	0,45	neutral	0,38	neutral	0,24	neutral	0,19	neutral	0,45	1	neutral	0,29	deleterious	0,72	neutral	-6	deleterious	0,69	medium_impact	-0,55	medium_impact	0,61	medium_impact	-0,68	0,56	0,8	20,48	25,11	N	0,37	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11495	11495	C	T	MI.17869	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	736	246	L	F	Ctc/Ttc	-2,5	0	0	benign	0,11	neutral	0,43	neutral	4,41	neutral	-0,17	neutral	-1,88	neutral_impact	0,55	neutral	0,75	neutral	0,77	deleterious	4,06	23,7	0,23	0,45	disease	0,75	neutral	0,49	neutral	0,37	neutral	0,45	1	neutral	0,5	deleterious	0,66	neutral	-6	deleterious	0,78	medium_impact	0,14	medium_impact	0,13	medium_impact	-0,58	0,5	0,8	20,48	25,11	N	0,33	N	0,27	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8527	8527	A	C	MI.1787	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	162	54	K	N	aaA/aaC	2,21	1	0	probably_damaging	0,99	neutral	0,44	neutral	1,69	deleterious	-5,5	deleterious	-4,62	high_impact	3,52	neutral	0,98	neutral	0,45	deleterious	3,93	23,5	0,37793802	0,85	disease	0,73	disease	0,66	disease	0,68	disease	0,63	3	deleterious	0,99	neutral	0,23	deleterious	2	deleterious	0,84	low_impact	-2,65	medium_impact	0,23	medium_impact	1,92	0,38	0,85	16,18	8,12	P	0,54	P	0,71	disease_causing	0,94	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11495	11495	C	A	MI.17870	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	736	246	L	I	Ctc/Atc	-2,5	0	0	benign	0,09	neutral	1	neutral	4,4	neutral	-0,53	neutral	1,04	neutral_impact	-0,74	neutral	0,72	neutral	0,97	neutral	1,43	12,94	0,3	0,45	neutral	0,35	neutral	0,05	neutral	0,12	neutral	0,21	6	neutral	0,09	deleterious	0,96	neutral	-6	deleterious	0,66	medium_impact	0,23	high_impact	1,88	low_impact	-1,86	0,54	0,8	20,48	25,11	N	0,41	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11496	11496	T	A	MI.17871	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	737	246	L	H	cTc/cAc	-0,2	0	0	probably_damaging	0,98	deleterious	0	neutral	4,26	deleterious	-4,8	deleterious	-4,31	medium_impact	2,98	neutral	0,72	neutral	0,57	deleterious	4,2	23,9	0,04	0,35	neutral	0,4	disease	0,65	disease	0,61	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,74	low_impact	-2,31	low_impact	-1,48	medium_impact	1,82	0,23	0,8	20,48	25,11	N	0,39	N	0,82	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11496	11496	T	C	MI.17872	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	737	246	L	P	cTc/cCc	-0,2	0	0	probably_damaging	0,96	deleterious	0	neutral	4,26	deleterious	-4,74	deleterious	-4,26	medium_impact	2,63	neutral	0,63	neutral	0,44	deleterious	3,97	23,6	0,02	0,35	disease	0,62	disease	0,87	disease	0,66	disease	0,79	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,86	low_impact	-2,01	low_impact	-1,48	medium_impact	1,48	0,22	0,8	20,48	25,11	N	0,31	N	0,93	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11496	11496	T	G	MI.17873	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	737	246	L	R	cTc/cGc	-0,2	0	0	probably_damaging	0,93	deleterious	0,04	neutral	4,26	deleterious	-3,19	deleterious	-4,11	medium_impact	2,98	neutral	0,69	neutral	0,51	deleterious	4,26	23,9	0,04	0,35	neutral	0,38	disease	0,88	disease	0,66	disease	0,79	6	deleterious	0,99	neutral	0,06	deleterious	5	deleterious	0,81	low_impact	-1,77	medium_impact	-0,57	medium_impact	1,82	0,15	0,8	20,48	25,11	N	0,39	N	0,91	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11498	11498	A	C	MI.17874	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	739	247	T	P	Aca/Cca	-8,72	0	0	possibly_damaging	0,72	neutral	0,16	neutral	4,53	neutral	-2,99	deleterious	-3,02	medium_impact	2,6	neutral	0,65	neutral	0,34	deleterious	1,83	15,15	0,03	0,35	neutral	0,39	disease	0,85	disease	0,71	disease	0,74	5	neutral	0,87	neutral	0,22	NA	0	deleterious	0,54	low_impact	-1,1	medium_impact	-0,2	medium_impact	1,45	0,39	0,8	25,05	20,69	N	0,33	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11498	11498	A	G	MI.17875	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	739	247	T	A	Aca/Gca	-8,72	0	0	benign	0,01	neutral	0,47	neutral	4,59	neutral	-0,8	neutral	-1,81	low_impact	1,28	neutral	0,77	neutral	0,74	deleterious	0,52	7,55	0,2	0,45	disease	0,61	neutral	0,5	neutral	0,45	neutral	0,49	0	neutral	0,52	deleterious	0,73	neutral	-6	neutral	0,22	medium_impact	1,16	medium_impact	0,17	medium_impact	0,14	0,45	0,8	25,05	20,69	N	0,28	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11498	11498	A	T	MI.17876	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	739	247	T	S	Aca/Tca	-8,72	0	0	benign	0,25	neutral	0,84	neutral	4,69	neutral	0,43	neutral	-0,97	neutral_impact	-0,18	neutral	0,7	neutral	0,97	neutral	-0,18	1,24	0,38	0,5	disease	0,51	neutral	0,28	neutral	0,25	neutral	0,38	2	neutral	0,14	deleterious	0,8	neutral	-6	neutral	0,19	medium_impact	-0,27	medium_impact	0,61	low_impact	-1,3	0,73	0,85	25,05	20,69	N	0,3	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11499	11499	C	T	MI.17877	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	740	247	T	M	aCa/aTa	0,26	0	0	benign	0,06	neutral	0,99	neutral	4,57	neutral	-1,15	neutral	-1,52	low_impact	0,86	neutral	0,68	neutral	0,88	deleterious	0,32	5,91	0,1	0,4	disease	0,8	neutral	0,3	neutral	0,3	disease	0,64	3	neutral	0,03	deleterious	0,97	neutral	-6	neutral	0,2	medium_impact	0,41	medium_impact	1,32	medium_impact	-0,28	0,64	0,8	25,05	20,69	N	0,26	N	0,15	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11499	11499	C	A	MI.17878	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	740	247	T	K	aCa/aAa	0,26	0	0	possibly_damaging	0,45	neutral	0,34	neutral	4,55	neutral	-1,98	deleterious	-2,61	medium_impact	2,26	neutral	0,75	neutral	0,41	deleterious	2,56	19,88	0,05	0,35	disease	0,57	disease	0,82	disease	0,62	disease	0,71	4	neutral	0,62	neutral	0,45	NA	0	neutral	0,32	medium_impact	-0,64	medium_impact	0,04	medium_impact	1,11	0,52	0,8	25,05	20,69	N	0,31	N	0,78	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11501	11501	C	G	MI.17879	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	742	248	L	V	Ctc/Gtc	-4,35	0	0	benign	0,07	neutral	0,59	neutral	4,57	neutral	-1,44	neutral	0,31	low_impact	1,26	neutral	0,72	neutral	0,98	neutral	-0,45	0,3	0,35	0,5	neutral	0,44	neutral	0,28	neutral	0,2	neutral	0,44	1	neutral	0,34	deleterious	0,76	neutral	-6	neutral	0,15	medium_impact	0,34	medium_impact	0,29	medium_impact	0,12	0,61	0,8	21,79	16,34	N	0,4	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8528	8528	T	G	MI.1788	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	163	55	W	G	Tga/Gga	5,68	1	0	probably_damaging	0,98	neutral	0,34	neutral	-0,53	deleterious	-11,1	deleterious	-12,02	high_impact	3,7	neutral	0,84	damaging	0,1	deleterious	3,96	23,6	0,13200123	0,85	disease	0,85	disease	0,71	disease	0,81	disease	0,76	5	deleterious	0,98	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-2,36	medium_impact	0,13	high_impact	2,07	0,06	0,85	19,12	8,82	P	0,64	P	0,93	disease_causing	0,98	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11501	11501	C	T	MI.17880	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	742	248	L	F	Ctc/Ttc	-4,35	0	0	benign	0,38	neutral	0,7	neutral	4,56	neutral	-1,43	neutral	-1,68	low_impact	1,38	neutral	0,78	neutral	0,88	deleterious	2,26	17,9	0,23	0,45	neutral	0,4	neutral	0,4	neutral	0,19	neutral	0,45	1	neutral	0,29	deleterious	0,66	neutral	-6	neutral	0,43	medium_impact	-0,52	medium_impact	0,41	medium_impact	0,24	0,54	0,8	21,79	16,34	N	0,35	N	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11501	11501	C	A	MI.17881	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	742	248	L	I	Ctc/Atc	-4,35	0	0	benign	0,01	neutral	0,65	neutral	4,62	neutral	-1,62	neutral	0,42	low_impact	0,86	neutral	0,75	neutral	1	neutral	-0,54	0,18	0,31	0,45	neutral	0,43	neutral	0,17	neutral	0,17	neutral	0,31	4	neutral	0,33	deleterious	0,82	neutral	-6	neutral	0,11	medium_impact	1,16	medium_impact	0,35	medium_impact	-0,28	0,48	0,8	21,79	16,34	N	0,45	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11502	11502	T	G	MI.17882	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	743	248	L	R	cTc/cGc	-3,42	0	0	possibly_damaging	0,47	neutral	0,33	neutral	4,56	deleterious	-4,55	deleterious	-2,66	medium_impact	2,52	neutral	0,72	neutral	0,51	deleterious	3,95	23,6	0,02	0,35	neutral	0,35	disease	0,82	disease	0,52	disease	0,73	5	neutral	0,63	neutral	0,43	NA	0	deleterious	0,63	medium_impact	-0,67	medium_impact	0,03	medium_impact	1,37	0,15	0,8	21,79	16,34	N	0,35	N	0,26	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11502	11502	T	A	MI.17883	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	743	248	L	H	cTc/cAc	-3,42	0	0	possibly_damaging	0,79	neutral	0,53	neutral	4,53	deleterious	-4,79	deleterious	-3	medium_impact	2,87	neutral	0,78	neutral	0,58	deleterious	4,11	23,8	0,04	0,35	neutral	0,41	disease	0,61	neutral	0,29	neutral	0,46	1	neutral	0,76	neutral	0,37	NA	0	deleterious	0,64	low_impact	-1,26	medium_impact	0,23	medium_impact	1,71	0,12	0,8	21,79	16,34	N	0,28	N	0,31	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11502	11502	T	C	MI.17884	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	743	248	L	P	cTc/cCc	-3,42	0	0	benign	0,01	neutral	0,27	neutral	4,63	neutral	-0,82	neutral	-2,08	neutral_impact	-0,4	neutral	0,77	neutral	0,92	deleterious	0,73	9,05	0,02	0,35	disease	0,7	disease	0,61	neutral	0,38	neutral	0,49	0	neutral	0,73	deleterious	0,63	neutral	-6	neutral	0,25	medium_impact	1,16	medium_impact	-0,04	low_impact	-1,52	0,11	0,8	21,79	16,34	N	0,31	N	0,01	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11504	11504	A	G	MI.17885	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	745	249	I	V	Att/Gtt	-10,33	0	0	benign	0,05	neutral	0,43	neutral	4,56	neutral	-0,73	neutral	-0,5	low_impact	1,49	neutral	0,74	neutral	0,93	neutral	-0,36	0,49	0,58	0,65	disease	0,76	neutral	0,28	neutral	0,35	disease	0,58	2	neutral	0,53	deleterious	0,69	neutral	-6	neutral	0,16	medium_impact	0,48	medium_impact	0,13	medium_impact	0,35	0,28	0,8	9,8	13,79	N	0,4	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11504	11504	A	T	MI.17886	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	745	249	I	F	Att/Ttt	-10,33	0	0	possibly_damaging	0,83	neutral	0,6	neutral	4,48	neutral	-1,97	neutral	-1,33	neutral_impact	0,56	neutral	0,77	neutral	0,97	deleterious	1,98	16,12	0,2	0,45	disease	0,63	neutral	0,5	neutral	0,34	neutral	0,49	0	neutral	0,8	neutral	0,39	neutral	-3	deleterious	0,56	low_impact	-1,37	medium_impact	0,3	medium_impact	-0,57	0,49	0,8	9,8	13,79	N	0,32	N	0,34	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11504	11504	A	C	MI.17887	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	745	249	I	L	Att/Ctt	-10,33	0	0	benign	0,05	neutral	1	neutral	4,84	neutral	1,01	neutral	0,07	neutral_impact	0,2	neutral	0,74	neutral	0,97	deleterious	-0,02	2,39	0,24	0,45	disease	0,52	neutral	0,32	neutral	0,23	neutral	0,37	3	neutral	0,05	deleterious	0,98	neutral	-6	neutral	0,17	medium_impact	0,48	high_impact	1,88	medium_impact	-0,93	0,49	0,8	9,8	13,79	N	0,3	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11505	11505	T	C	MI.17888	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	746	249	I	T	aTt/aCt	-1,12	0	0	possibly_damaging	0,75	neutral	0,38	neutral	4,48	neutral	-2,01	deleterious	-2,62	low_impact	0,82	neutral	0,7	neutral	0,8	deleterious	0,32	5,86	0,17	0,45	neutral	0,48	neutral	0,48	neutral	0,38	neutral	0,44	1	neutral	0,77	neutral	0,32	neutral	-3	neutral	0,39	low_impact	-1,17	medium_impact	0,08	medium_impact	-0,32	0,12	0,8	9,8	13,79	N	0,32	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11505	11505	T	G	MI.17889	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	746	249	I	S	aTt/aGt	-1,12	0	0	probably_damaging	0,9	neutral	0,38	neutral	4,49	neutral	-1,83	deleterious	-3,24	low_impact	1,62	neutral	0,79	neutral	0,77	deleterious	2,73	21	0,04	0,35	disease	0,7	disease	0,71	disease	0,65	disease	0,66	3	neutral	0,91	neutral	0,24	neutral	-2	deleterious	0,51	low_impact	-1,61	medium_impact	0,08	medium_impact	0,48	0,09	0,8	9,8	13,79	N	0,27	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8528	8528	T	C	MI.1789	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	163	55	W	R	Tga/Cga	5,68	1	0	probably_damaging	1	neutral	0,31	neutral	-0,53	deleterious	-11,02	deleterious	-12,74	high_impact	3,7	neutral	0,85	damaging	0,06	deleterious	3,65	23,2	0,15055088	0,85	disease	0,89	disease	0,74	disease	0,84	disease	0,77	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,1	high_impact	2,07	0,08	0,85	19,12	8,82	P	0,58	P	0,97	disease_causing_automatic	0,95	0,25	rs387906422	Pathogenic	Cardiomyopathy,_infantile_hypertrophic	RCV000010272.6	MedGen:OMIM	.	.	.	.	T8528C	Infantile cardiomyopathy	+	+	Confirmed	3
chrM	11505	11505	T	A	MI.17890	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	746	249	I	N	aTt/aAt	-1,12	0	0	probably_damaging	0,96	neutral	0,08	neutral	4,44	deleterious	-3,5	deleterious	-4,11	medium_impact	2,06	neutral	0,77	neutral	0,47	deleterious	4,32	24	0,1	0,4	disease	0,64	disease	0,75	disease	0,66	disease	0,71	4	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,71	low_impact	-2,01	medium_impact	-0,39	medium_impact	0,91	0,08	0,8	9,8	13,79	N	0,3	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11506	11506	T	G	MI.17891	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	747	249	I	M	atT/atG	3,02	0,71	0	probably_damaging	0,9	neutral	0,72	neutral	4,48	neutral	-1,93	neutral	0,11	neutral_impact	0,46	neutral	0,71	neutral	0,98	deleterious	0,6	8,13	0,35	0,5	disease	0,73	neutral	0,2	neutral	0,28	disease	0,51	0	neutral	0,89	neutral	0,41	neutral	-2	deleterious	0,56	low_impact	-1,61	medium_impact	0,43	medium_impact	-0,67	0,56	0,8	9,8	13,79	N	0,41	N	0,61	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11506	11506	T	A	MI.17892	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	747	249	I	M	atT/atA	3,02	0,71	0	probably_damaging	0,9	neutral	0,72	neutral	4,48	neutral	-1,93	neutral	0,11	neutral_impact	0,46	neutral	0,71	neutral	0,98	neutral	0,95	10,35	0,35	0,5	disease	0,73	neutral	0,2	neutral	0,28	disease	0,51	0	neutral	0,89	neutral	0,41	neutral	-2	deleterious	0,56	low_impact	-1,61	medium_impact	0,43	medium_impact	-0,67	0,56	0,8	9,8	13,79	N	0,41	N	0,61	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11507	11507	C	T	MI.17893	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	748	250	L	F	Ctc/Ttc	-7,57	0	0	probably_damaging	1	neutral	0,44	neutral	4,63	neutral	-0,76	deleterious	-3,14	low_impact	1,34	neutral	0,71	damaging	0,23	deleterious	4,03	23,6	0,21	0,45	disease	0,87	neutral	0,43	neutral	0,31	disease	0,65	3	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,79	low_impact	-3,54	medium_impact	0,14	medium_impact	0,2	0,42	0,8	15,69	22,83	N	0,26	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11507	11507	C	A	MI.17894	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	748	250	L	I	Ctc/Atc	-7,57	0	0	probably_damaging	1	neutral	0,17	neutral	4,61	neutral	-1,59	neutral	-1,46	low_impact	1,57	neutral	0,78	neutral	0,31	deleterious	4,1	23,7	0,35	0,5	disease	0,58	disease	0,64	neutral	0,27	neutral	0,47	1	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	-0,18	medium_impact	0,43	0,37	0,8	15,69	22,83	N	0,32	N	0,17	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11507	11507	C	G	MI.17895	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	748	250	L	V	Ctc/Gtc	-7,57	0	0	probably_damaging	1	neutral	0,07	neutral	4,53	neutral	-1,62	neutral	-2,2	medium_impact	2,4	neutral	0,72	damaging	0,23	deleterious	3,48	23,1	0,36	0,5	disease	0,69	disease	0,66	neutral	0,32	neutral	0,47	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,43	medium_impact	1,25	0,43	0,8	15,69	22,83	N	0,34	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11508	11508	T	G	MI.17896	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	749	250	L	R	cTc/cGc	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-4,93	deleterious	-4,77	high_impact	4,07	damaging	0,59	damaging	0,11	deleterious	4,19	23,9	0,02	0,35	neutral	0,43	disease	0,91	disease	0,73	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	2,9	0,06	0,8	15,69	22,83	N	0,37	N	0,98	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11508	11508	T	A	MI.17897	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	749	250	L	H	cTc/cAc	-0,2	0	0	probably_damaging	1	deleterious	0,01	neutral	4,44	deleterious	-5,3	deleterious	-5,58	high_impact	4,07	neutral	0,64	damaging	0,1	deleterious	4,07	23,7	0,05	0,35	disease	0,65	disease	0,82	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,54	medium_impact	-0,92	high_impact	2,9	0,12	0,8	15,69	22,83	N	0,31	N	0,86	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11508	11508	T	C	MI.17898	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	749	250	L	P	cTc/cCc	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	4,46	deleterious	-4,96	deleterious	-5,54	high_impact	3,73	damaging	0,56	damaging	0,13	deleterious	3,94	23,5	0,02	0,35	disease	0,53	disease	0,87	disease	0,73	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,56	0,12	0,8	15,69	22,83	N	0,32	N	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11510	11510	A	C	MI.17899	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	751	251	N	H	Aac/Cac	-11,71	0	0	possibly_damaging	0,89	neutral	0,54	neutral	4,58	neutral	-1,19	neutral	-1,94	medium_impact	1,95	neutral	0,79	neutral	0,86	deleterious	2,79	21,3	0,33	0,5	disease	0,63	disease	0,51	neutral	0,33	neutral	0,5	0	neutral	0,87	neutral	0,33	NA	0	deleterious	0,51	low_impact	-1,57	medium_impact	0,24	medium_impact	0,8	0,23	0,8	28,32	21,7	N	0,28	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8609	8609	C	A	MI.179	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	83	28	P	H	cCt/cAt	-0,57	0	0	possibly_damaging	0,9	neutral	0,09	neutral	4,39	neutral	0,05	neutral	-0,22	neutral_impact	0,46	neutral	0,87	neutral	0,43	deleterious	2,05	16,56	0,3	0,65	disease	0,7	neutral	0,29	neutral	0,49	disease	0,61	2	neutral	0,97	neutral	0,1	neutral	-3	deleterious	0,69	low_impact	-1,66	medium_impact	-0,28	medium_impact	-0,7	0,59	0,9	31,86	20,94	N	0,45	N	0,53	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8529	8529	G	T	MI.1790	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	164	55	W	L	tGa/tTa	7,53	1	0	probably_damaging	0,98	neutral	0,69	neutral	-0,52	deleterious	-8,9	deleterious	-12,02	high_impact	3,7	neutral	0,84	damaging	0,06	deleterious	4,28	24	0,09988831	0,85	disease	0,79	disease	0,71	disease	0,8	disease	0,73	5	deleterious	0,98	neutral	0,36	deleterious	2	deleterious	0,86	low_impact	-2,36	medium_impact	0,49	high_impact	2,07	0,06	0,85	19,12	8,82	P	0,58	P	0,96	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11510	11510	A	G	MI.17900	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	751	251	N	D	Aac/Gac	-11,71	0	0	benign	0,01	neutral	0,3	neutral	4,6	neutral	-0,64	neutral	0,39	low_impact	1,72	neutral	0,74	neutral	0,98	neutral	-0,81	0,04	0,46	0,55	disease	0,59	neutral	0,32	neutral	0,34	disease	0,6	2	neutral	0,69	deleterious	0,65	neutral	-6	neutral	0,14	medium_impact	1,16	medium_impact	0	medium_impact	0,58	0,29	0,8	28,32	21,7	N	0,47	N	0,13	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11510	11510	A	T	MI.17901	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	751	251	N	Y	Aac/Tac	-11,71	0	0	possibly_damaging	0,89	neutral	1	neutral	4,54	neutral	-2,84	deleterious	-3,74	low_impact	1,42	neutral	0,8	neutral	0,69	deleterious	3,35	22,9	0,13	0,4	neutral	0,4	disease	0,61	neutral	0,38	neutral	0,47	1	neutral	0,89	deleterious	0,56	neutral	-3	deleterious	0,53	low_impact	-1,57	high_impact	1,88	medium_impact	0,28	0,17	0,8	28,32	21,7	N	0,22	N	0,93	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11511	11511	A	G	MI.17902	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	752	251	N	S	aAc/aGc	0,03	0	0	benign	0,04	neutral	0,49	neutral	4,7	neutral	0,6	neutral	-1,38	low_impact	0,83	neutral	0,73	neutral	0,97	deleterious	0,39	6,57	0,42	0,5	disease	0,6	neutral	0,35	neutral	0,26	disease	0,61	2	neutral	0,47	deleterious	0,73	neutral	-6	neutral	0,15	medium_impact	0,58	medium_impact	0,19	medium_impact	-0,31	0,27	0,8	28,32	21,7	N	0,39	N	0,31	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11511	11511	A	C	MI.17903	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	752	251	N	T	aAc/aCc	0,03	0	0	benign	0,32	neutral	0,46	neutral	4,59	neutral	-0,99	neutral	-1,92	low_impact	1,3	neutral	0,68	neutral	0,84	deleterious	0,49	7,37	0,27	0,45	disease	0,71	neutral	0,32	neutral	0,38	disease	0,64	3	neutral	0,45	deleterious	0,57	neutral	-6	neutral	0,19	medium_impact	-0,41	medium_impact	0,16	medium_impact	0,16	0,37	0,8	28,32	21,7	N	0,39	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11511	11511	A	T	MI.17904	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	752	251	N	I	aAc/aTc	0,03	0	0	possibly_damaging	0,85	neutral	0,42	neutral	4,58	neutral	-1,12	deleterious	-4,2	low_impact	1,46	neutral	0,79	neutral	0,63	deleterious	2,79	21,3	0,16	0,45	disease	0,67	disease	0,7	neutral	0,39	disease	0,54	1	neutral	0,85	neutral	0,29	neutral	-3	neutral	0,34	low_impact	-1,43	medium_impact	0,12	medium_impact	0,32	0,12	0,8	28,32	21,7	N	0,27	N	0,9	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11512	11512	C	A	MI.17905	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	753	251	N	K	aaC/aaA	0,03	0	0	possibly_damaging	0,44	neutral	0,36	neutral	4,64	neutral	-0,02	neutral	-2,02	low_impact	1,46	neutral	0,77	neutral	0,5	deleterious	2,6	20,2	0,4	0,5	disease	0,53	disease	0,65	neutral	0,5	neutral	0,49	0	neutral	0,59	neutral	0,46	neutral	-3	neutral	0,23	medium_impact	-0,62	medium_impact	0,06	medium_impact	0,32	0,31	0,8	28,32	21,7	N	0,3	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11512	11512	C	G	MI.17906	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	753	251	N	K	aaC/aaG	0,03	0	0	possibly_damaging	0,44	neutral	0,36	neutral	4,64	neutral	-0,02	neutral	-2,02	low_impact	1,46	neutral	0,77	neutral	0,5	deleterious	2,16	17,25	0,4	0,5	disease	0,53	disease	0,65	neutral	0,5	neutral	0,49	0	neutral	0,59	neutral	0,46	neutral	-3	neutral	0,23	medium_impact	-0,62	medium_impact	0,06	medium_impact	0,32	0,31	0,8	28,32	21,7	N	0,3	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11513	11513	C	G	MI.17907	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	754	252	P	A	Ccc/Gcc	-5,5	0	0	probably_damaging	0,92	neutral	0,51	neutral	1,98	neutral	-2,14	deleterious	-6,79	medium_impact	2,94	neutral	0,69	damaging	0,21	deleterious	3,13	22,6	0,38	0,5	neutral	0,37	disease	0,61	neutral	0,33	neutral	0,48	0	neutral	0,92	neutral	0,3	deleterious	1	deleterious	0,72	low_impact	-1,71	medium_impact	0,21	medium_impact	1,78	0,53	0,8	39,43	8,08	N	0,29	N	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11513	11513	C	T	MI.17908	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	754	252	P	S	Ccc/Tcc	-5,5	0	0	probably_damaging	0,98	neutral	0,45	neutral	1,96	neutral	-2,7	deleterious	-6,78	medium_impact	1,96	neutral	0,76	damaging	0,21	deleterious	3,87	23,5	0,38	0,5	neutral	0,49	disease	0,72	neutral	0,19	neutral	0,45	1	deleterious	0,98	neutral	0,24	deleterious	1	deleterious	0,75	low_impact	-2,31	medium_impact	0,15	medium_impact	0,81	0,11	0,8	39,43	8,08	N	0,32	N	0,71	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11513	11513	C	A	MI.17909	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	754	252	P	T	Ccc/Acc	-5,5	0	0	probably_damaging	0,98	neutral	0,43	neutral	1,94	deleterious	-3,25	deleterious	-6,81	low_impact	1,68	neutral	0,71	damaging	0,25	deleterious	3,89	23,5	0,32	0,5	disease	0,62	disease	0,74	neutral	0,17	neutral	0,48	0	neutral	0,98	neutral	0,23	neutral	-2	deleterious	0,77	low_impact	-2,31	medium_impact	0,13	medium_impact	0,54	0,34	0,8	39,43	8,08	N	0,34	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8529	8529	G	C	MI.1791	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	164	55	W	S	tGa/tCa	7,53	1	0	probably_damaging	0,99	neutral	0,4	neutral	-0,53	deleterious	-10,54	deleterious	-12,78	high_impact	3,7	neutral	0,83	damaging	0,07	deleterious	4,06	23,7	0,11512998	0,85	disease	0,88	disease	0,8	disease	0,8	disease	0,79	6	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,9	low_impact	-2,65	medium_impact	0,19	high_impact	2,07	0,03	0,85	19,12	8,82	P	0,59	P	0,95	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11514	11514	C	G	MI.17910	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	755	252	P	R	cCc/cGc	3,48	0,71	0	probably_damaging	0,99	neutral	0,34	neutral	1,92	deleterious	-3,47	deleterious	-7,71	medium_impact	3,29	neutral	0,62	damaging	0,14	deleterious	3,7	23,3	0,09	0,35	disease	0,66	disease	0,9	neutral	0,49	disease	0,7	4	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,83	low_impact	-2,59	medium_impact	0,04	high_impact	2,13	0,24	0,8	39,43	8,08	N	0,42	N	0,58	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11514	11514	C	T	MI.17911	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	755	252	P	L	cCc/cTc	3,48	0,71	0	benign	0,38	neutral	0,67	neutral	1,92	deleterious	-3,51	deleterious	-8,52	low_impact	1,88	neutral	0,67	damaging	0,15	deleterious	4,45	24,2	0,21	0,45	disease	0,53	disease	0,85	neutral	0,36	disease	0,53	1	neutral	0,3	deleterious	0,65	neutral	-6	deleterious	0,77	medium_impact	-0,52	medium_impact	0,37	medium_impact	0,73	0,54	0,8	39,43	8,08	N	0,33	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11514	11514	C	A	MI.17912	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	755	252	P	H	cCc/cAc	3,48	0,71	0	probably_damaging	1	neutral	0,51	neutral	1,89	deleterious	-4,1	deleterious	-7,73	medium_impact	3,09	neutral	0,7	damaging	0,14	deleterious	4,07	23,7	0,14	0,4	disease	0,83	disease	0,84	neutral	0,32	disease	0,71	4	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	0,21	medium_impact	1,93	0,12	0,8	39,43	8,08	N	0,36	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11516	11516	C	A	MI.17913	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	757	253	L	M	Ctg/Atg	-14,01	0	0	probably_damaging	0,96	neutral	0,21	neutral	4,62	neutral	-0,63	neutral	-0,8	low_impact	1,31	neutral	0,76	neutral	0,97	deleterious	2,66	20,6	0,31	0,45	disease	0,74	neutral	0,29	neutral	0,22	disease	0,61	2	neutral	0,97	neutral	0,13	neutral	-2	deleterious	0,72	low_impact	-2,01	medium_impact	-0,12	medium_impact	0,17	0,49	0,8	16,56	14,33	N	0,47	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11516	11516	C	G	MI.17914	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	757	253	L	V	Ctg/Gtg	-14,01	0	0	possibly_damaging	0,52	neutral	0,41	neutral	4,67	neutral	0,54	neutral	-1,13	low_impact	1,08	neutral	0,8	neutral	0,95	deleterious	2,4	18,81	0,27	0,45	disease	0,65	neutral	0,43	neutral	0,36	disease	0,61	2	neutral	0,58	neutral	0,45	neutral	-3	deleterious	0,72	medium_impact	-0,75	medium_impact	0,11	medium_impact	-0,06	0,28	0,8	16,56	14,33	N	0,35	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11517	11517	T	A	MI.17915	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	758	253	L	Q	cTg/cAg	-13,32	0	0	probably_damaging	0,97	neutral	0,23	neutral	4,64	neutral	-0,03	deleterious	-3,81	low_impact	1,08	neutral	0,82	neutral	0,87	deleterious	4,2	23,9	0,14	0,4	disease	0,9	disease	0,71	neutral	0,26	disease	0,61	2	neutral	0,98	neutral	0,13	neutral	-2	deleterious	0,81	low_impact	-2,14	medium_impact	-0,09	medium_impact	-0,06	0,2	0,8	16,56	14,33	N	0,34	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11517	11517	T	C	MI.17916	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	758	253	L	P	cTg/cCg	-13,32	0	0	probably_damaging	0,97	neutral	0,15	neutral	4,6	neutral	-1,47	deleterious	-4,52	medium_impact	1,94	neutral	0,72	neutral	0,69	deleterious	3,89	23,5	0,1	0,4	disease	0,93	disease	0,81	neutral	0,17	disease	0,69	4	deleterious	0,98	neutral	0,09	deleterious	1	deleterious	0,87	low_impact	-2,14	medium_impact	-0,22	medium_impact	0,79	0,23	0,8	16,56	14,33	N	0,42	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11517	11517	T	G	MI.17917	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	758	253	L	R	cTg/cGg	-13,32	0	0	probably_damaging	0,96	neutral	0,22	neutral	4,64	neutral	-0,18	deleterious	-3,98	medium_impact	3,29	neutral	0,69	neutral	0,45	deleterious	4,23	23,9	0,1	0,4	disease	0,91	disease	0,86	disease	0,58	disease	0,76	5	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,87	low_impact	-2,01	medium_impact	-0,11	high_impact	2,13	0,16	0,8	16,56	14,33	N	0,37	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11519	11519	A	C	MI.17918	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	760	254	T	P	Aca/Cca	-5,73	0	0	probably_damaging	0,98	neutral	0,18	neutral	4,6	neutral	-0,88	deleterious	-4,38	low_impact	1,7	neutral	0,7	neutral	0,53	deleterious	3,52	23,1	0,09	0,35	disease	0,56	disease	0,83	neutral	0,41	disease	0,55	1	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,82	low_impact	-2,31	medium_impact	-0,17	medium_impact	0,56	0,17	0,8	19,61	9,78	N	0,32	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11519	11519	A	T	MI.17919	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	760	254	T	S	Aca/Tca	-5,73	0	0	possibly_damaging	0,86	neutral	1	neutral	4,75	neutral	-0,14	neutral	-2,06	neutral_impact	0,74	neutral	0,65	neutral	0,64	deleterious	1,98	16,09	0,4	0,5	neutral	0,25	neutral	0,29	neutral	0,21	neutral	0,44	1	neutral	0,85	deleterious	0,57	neutral	-3	deleterious	0,68	low_impact	-1,46	high_impact	1,88	medium_impact	-0,39	0,38	0,8	19,61	9,78	N	0,34	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8530	8530	A	C	MI.1792	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	165	55	W	C	tgA/tgC	7,3	1	0	probably_damaging	1	neutral	0,21	neutral	-0,53	deleterious	-12,01	deleterious	-12,04	high_impact	3,7	neutral	0,92	damaging	0,05	deleterious	4,07	23,7	0,12589835	0,85	disease	0,94	disease	0,77	disease	0,83	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,03	high_impact	2,07	0,06	0,85	19,12	8,82	P	0,6	P	0,92	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11519	11519	A	G	MI.17920	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	760	254	T	A	Aca/Gca	-5,73	0	0	benign	0,22	neutral	0,52	neutral	4,69	neutral	0,77	deleterious	-3,36	low_impact	1,12	neutral	0,77	neutral	0,65	deleterious	3,51	23,1	0,29	0,45	neutral	0,22	neutral	0,48	neutral	0,41	neutral	0,46	1	neutral	0,37	deleterious	0,65	neutral	-6	deleterious	0,7	medium_impact	-0,2	medium_impact	0,22	medium_impact	-0,02	0,24	0,8	19,61	9,78	N	0,29	N	0,69	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11520	11520	C	A	MI.17921	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	761	254	T	K	aCa/aAa	0,03	0	0	probably_damaging	0,96	neutral	0,25	neutral	4,64	neutral	-1,36	deleterious	-4,11	low_impact	1,17	neutral	0,75	neutral	0,51	deleterious	4,44	24,2	0,1	0,4	disease	0,6	disease	0,8	disease	0,57	disease	0,55	1	neutral	0,97	neutral	0,15	neutral	-2	deleterious	0,8	low_impact	-2,01	medium_impact	-0,07	medium_impact	0,03	0,42	0,8	19,61	9,78	N	0,31	N	1	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11520	11520	C	T	MI.17922	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	761	254	T	M	aCa/aTa	0,03	0	0	probably_damaging	0,99	neutral	0,23	neutral	4,59	neutral	-2,66	deleterious	-4,24	low_impact	1,7	neutral	0,77	neutral	0,61	deleterious	4,07	23,7	0,16	0,45	disease	0,52	disease	0,6	neutral	0,25	neutral	0,46	1	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,74	low_impact	-2,59	medium_impact	-0,09	medium_impact	0,56	0,48	0,8	19,61	9,78	N	0,35	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11522	11522	A	G	MI.17923	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	763	255	K	E	Aaa/Gaa	-2,96	0	0	benign	0,01	neutral	0,96	neutral	4,66	neutral	0,15	neutral	-0,73	neutral_impact	-0,26	neutral	0,83	neutral	0,95	deleterious	2,67	20,6	0,21	0,45	disease	0,5	disease	0,6	neutral	0,28	neutral	0,45	1	neutral	0,01	deleterious	0,98	neutral	-6	deleterious	0,73	medium_impact	1,16	medium_impact	0,98	low_impact	-1,38	0,33	0,8	24,4	15,88	N	0,19	N	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11522	11522	A	C	MI.17924	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	763	255	K	Q	Aaa/Caa	-2,96	0	0	benign	0,37	neutral	0,57	neutral	4,58	neutral	-0,95	neutral	-1,31	neutral_impact	0,5	neutral	0,8	neutral	0,79	deleterious	3,45	23	0,34	0,5	disease	0,53	disease	0,52	neutral	0,36	neutral	0,49	0	neutral	0,37	deleterious	0,6	neutral	-6	deleterious	0,7	medium_impact	-0,5	medium_impact	0,27	medium_impact	-0,63	0,23	0,8	24,4	15,88	N	0,23	N	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11523	11523	A	C	MI.17925	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	764	255	K	T	aAa/aCa	1,87	0	0	benign	0,34	neutral	0,6	neutral	4,6	neutral	-0,61	neutral	-2,33	neutral_impact	-0,78	neutral	0,75	neutral	0,96	deleterious	2,49	19,38	0,17	0,45	neutral	0,33	neutral	0,4	neutral	0,16	neutral	0,47	1	neutral	0,32	deleterious	0,63	neutral	-6	deleterious	0,69	medium_impact	-0,45	medium_impact	0,3	low_impact	-1,9	0,17	0,8	24,4	15,88	N	0,37	N	0,35	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11523	11523	A	T	MI.17926	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	764	255	K	M	aAa/aTa	1,87	0	0	probably_damaging	0,93	neutral	0,15	neutral	4,54	neutral	-2,46	deleterious	-2,97	neutral_impact	0,15	neutral	0,82	neutral	0,77	deleterious	3,8	23,4	0,14	0,4	neutral	0,31	neutral	0,48	neutral	0,22	neutral	0,44	1	neutral	0,96	neutral	0,11	neutral	-2	deleterious	0,68	low_impact	-1,77	medium_impact	-0,22	medium_impact	-0,98	0,15	0,8	24,4	15,88	N	0,37	N	0,62	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11524	11524	A	T	MI.17927	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	765	255	K	N	aaA/aaT	0,03	0	0	benign	0,02	neutral	0,59	neutral	4,69	neutral	0,5	neutral	-1,51	neutral_impact	-0,28	neutral	0,75	neutral	0,98	deleterious	2,71	20,9	0,51	0,6	neutral	0,31	neutral	0,44	neutral	0,25	neutral	0,46	1	neutral	0,38	deleterious	0,79	neutral	-6	deleterious	0,69	medium_impact	0,87	medium_impact	0,29	low_impact	-1,4	0,31	0,8	24,4	15,88	N	0,37	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11524	11524	A	C	MI.17928	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	765	255	K	N	aaA/aaC	0,03	0	0	benign	0,02	neutral	0,59	neutral	4,69	neutral	0,5	neutral	-1,51	neutral_impact	-0,28	neutral	0,75	neutral	0,98	deleterious	2,69	20,7	0,51	0,6	neutral	0,31	neutral	0,44	neutral	0,25	neutral	0,46	1	neutral	0,38	deleterious	0,79	neutral	-6	deleterious	0,69	medium_impact	0,87	medium_impact	0,29	low_impact	-1,4	0,31	0,8	24,4	15,88	N	0,37	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11525	11525	C	A	MI.17929	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	766	256	H	N	Cac/Aac	-2,5	0	0	benign	0,18	neutral	0,56	neutral	4,73	neutral	-0,17	neutral	0,25	neutral_impact	-0,56	neutral	0,75	neutral	0,94	deleterious	2,56	19,88	0,37	0,5	neutral	0,38	neutral	0,3	neutral	0,31	neutral	0,46	1	neutral	0,33	deleterious	0,69	neutral	-6	deleterious	0,66	medium_impact	-0,1	medium_impact	0,26	low_impact	-1,68	0,41	0,8	31,59	21,45	N	0,3	N	0,38	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8530	8530	A	T	MI.1793	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	165	55	W	C	tgA/tgT	7,3	1	0	probably_damaging	1	neutral	0,21	neutral	-0,53	deleterious	-12,01	deleterious	-12,04	high_impact	3,7	neutral	0,92	damaging	0,05	deleterious	4,16	23,8	0,12589835	0,85	disease	0,94	disease	0,77	disease	0,83	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,03	high_impact	2,07	0,06	0,85	19,12	8,82	P	0,6	P	0,92	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11525	11525	C	G	MI.17930	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	766	256	H	D	Cac/Gac	-2,5	0	0	benign	0	neutral	0,3	neutral	4,73	neutral	0,35	neutral	-0,08	neutral_impact	0,08	neutral	0,72	neutral	0,8	deleterious	2,37	18,65	0,08	0,35	disease	0,78	neutral	0,45	neutral	0,4	disease	0,64	3	neutral	0,7	deleterious	0,65	neutral	-6	deleterious	0,76	high_impact	2,1	medium_impact	0	low_impact	-1,05	0,43	0,8	31,59	21,45	N	0,42	N	0,54	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11525	11525	C	T	MI.17931	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	766	256	H	Y	Cac/Tac	-2,5	0	0	benign	0	neutral	1	neutral	4,64	neutral	-0,49	neutral	-0,55	neutral_impact	-0,1	neutral	0,83	neutral	0,97	deleterious	1,92	15,73	0,23	0,45	neutral	0,39	neutral	0,34	neutral	0,26	neutral	0,46	1	neutral	0	deleterious	1	neutral	-6	deleterious	0,69	high_impact	2,1	high_impact	1,88	low_impact	-1,23	0,13	0,8	31,59	21,45	N	0,3	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11526	11526	A	G	MI.17932	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	767	256	H	R	cAc/cGc	-2,04	0	0	benign	0,18	neutral	0,39	neutral	4,67	neutral	-0,38	neutral	-0,5	low_impact	0,9	neutral	0,8	neutral	0,52	neutral	1,69	14,35	0,19	0,45	disease	0,63	disease	0,54	neutral	0,42	disease	0,51	0	neutral	0,53	deleterious	0,61	neutral	-6	deleterious	0,76	medium_impact	-0,1	medium_impact	0,09	medium_impact	-0,24	0,13	0,8	31,59	21,45	N	0,31	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11526	11526	A	T	MI.17933	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	767	256	H	L	cAc/cTc	-2,04	0	0	benign	0,07	neutral	0,75	neutral	4,77	neutral	-0,24	neutral	-1,43	neutral_impact	-0,14	neutral	0,78	neutral	0,85	deleterious	2,33	18,37	0,1	0,4	disease	0,83	disease	0,52	neutral	0,43	disease	0,59	2	neutral	0,15	deleterious	0,84	neutral	-6	deleterious	0,71	medium_impact	0,34	medium_impact	0,47	low_impact	-1,26	0,16	0,8	31,59	21,45	N	0,23	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11526	11526	A	C	MI.17934	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	767	256	H	P	cAc/cCc	-2,04	0	0	possibly_damaging	0,48	neutral	0,25	neutral	4,64	neutral	-1,32	neutral	-1,39	neutral_impact	0,08	neutral	0,72	neutral	0,73	deleterious	2,07	16,66	0,07	0,35	disease	0,71	disease	0,77	disease	0,56	disease	0,74	5	neutral	0,72	neutral	0,39	neutral	-3	deleterious	0,83	medium_impact	-0,69	medium_impact	-0,07	low_impact	-1,05	0,27	0,8	31,59	21,45	N	0,31	N	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11527	11527	C	G	MI.17935	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	768	256	H	Q	caC/caG	-4,12	0	0	benign	0,26	neutral	0,38	neutral	4,68	neutral	0,17	neutral	0,18	neutral_impact	0,34	neutral	0,79	neutral	0,9	deleterious	2,13	17,04	0,24	0,45	disease	0,57	neutral	0,27	neutral	0,32	disease	0,56	1	neutral	0,54	deleterious	0,56	neutral	-6	deleterious	0,69	medium_impact	-0,29	medium_impact	0,08	medium_impact	-0,79	0,42	0,8	31,59	21,45	N	0,37	N	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11527	11527	C	A	MI.17936	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	768	256	H	Q	caC/caA	-4,12	0	0	benign	0,26	neutral	0,38	neutral	4,68	neutral	0,17	neutral	0,18	neutral_impact	0,34	neutral	0,79	neutral	0,9	deleterious	2,54	19,75	0,24	0,45	disease	0,57	neutral	0,27	neutral	0,32	disease	0,56	1	neutral	0,54	deleterious	0,56	neutral	-6	deleterious	0,69	medium_impact	-0,29	medium_impact	0,08	medium_impact	-0,79	0,42	0,8	31,59	21,45	N	0,37	N	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11528	11528	A	C	MI.17937	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	769	257	M	L	Ata/Cta	-4,58	0	0	probably_damaging	0,98	neutral	1	neutral	4,75	neutral	1,94	neutral	-1,28	neutral_impact	-0,29	neutral	0,65	neutral	0,87	deleterious	0,7	8,84	0,24	0,45	disease	0,51	neutral	0,23	neutral	0,4	neutral	0,34	3	deleterious	0,98	deleterious	0,51	neutral	-2	deleterious	0,5	low_impact	-2,31	high_impact	1,88	low_impact	-1,41	0,37	0,8	18,3	19,19	N	0,31	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11528	11528	A	G	MI.17938	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	769	257	M	V	Ata/Gta	-4,58	0	0	probably_damaging	0,99	neutral	0,24	neutral	4,7	neutral	0,88	deleterious	-2,6	low_impact	1	neutral	0,7	damaging	0,19	deleterious	2,51	19,53	0,2	0,45	disease	0,67	disease	0,6	disease	0,54	disease	0,53	1	deleterious	0,99	neutral	0,13	neutral	-2	deleterious	0,64	low_impact	-2,59	medium_impact	-0,08	medium_impact	-0,14	0,4	0,8	18,3	19,19	N	0,27	N	0,81	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11528	11528	A	T	MI.17939	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	769	257	M	L	Ata/Tta	-4,58	0	0	probably_damaging	0,98	neutral	1	neutral	4,75	neutral	1,94	neutral	-1,28	neutral_impact	-0,29	neutral	0,65	neutral	0,87	deleterious	0,8	9,47	0,24	0,45	disease	0,51	neutral	0,23	neutral	0,4	neutral	0,34	3	deleterious	0,98	deleterious	0,51	neutral	-2	deleterious	0,5	low_impact	-2,31	high_impact	1,88	low_impact	-1,41	0,37	0,8	18,3	19,19	N	0,34	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8531	8531	A	G	MI.1794	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	166	56	T	A	Acg/Gcg	6,84	1	0	possibly_damaging	0,9	neutral	0,51	neutral	0,9	deleterious	-4,04	deleterious	-4,64	high_impact	3,52	neutral	0,99	neutral	0,53	deleterious	3,55	23,1	0,51274914	0,85	neutral	0,38	neutral	0,38	disease	0,72	neutral	0,27	5	neutral	0,89	neutral	0,31	deleterious	1	deleterious	0,72	low_impact	-1,66	medium_impact	0,3	medium_impact	1,92	0,63	0,85	19,12	8,91	P	0,67	P	0,79	disease_causing	0,99	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11529	11529	T	A	MI.17940	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	770	257	M	K	aTa/aAa	-0,66	0	0	probably_damaging	1	deleterious	0,01	neutral	4,56	neutral	-1,84	deleterious	-4,62	medium_impact	2,19	neutral	0,61	damaging	0,12	deleterious	4,03	23,6	0,04	0,35	disease	0,78	disease	0,82	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,81	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,04	0,19	0,8	18,3	19,19	N	0,25	N	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11529	11529	T	C	MI.17941	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	770	257	M	T	aTa/aCa	-0,66	0	0	probably_damaging	1	neutral	0,09	neutral	4,6	neutral	-0,17	deleterious	-4,3	low_impact	1,66	neutral	0,77	damaging	0,24	deleterious	2,99	22,2	0,16	0,45	disease	0,52	disease	0,61	disease	0,53	disease	0,56	1	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,73	low_impact	-3,54	medium_impact	-0,36	medium_impact	0,52	0,21	0,8	18,3	19,19	N	0,3	N	0,91	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11530	11530	A	T	MI.17942	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	771	257	M	I	atA/atT	5,78	0,87	0	probably_damaging	0,99	neutral	0,29	neutral	4,74	neutral	0,59	neutral	-2,36	low_impact	1,12	neutral	0,74	damaging	0,21	deleterious	3,53	23,1	0,27	0,45	disease	0,59	disease	0,6	disease	0,51	neutral	0,49	0	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,69	low_impact	-2,59	medium_impact	-0,02	medium_impact	-0,02	0,43	0,8	18,3	19,19	N	0,47	N	0,78	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11530	11530	A	C	MI.17943	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	771	257	M	I	atA/atC	5,78	0,87	0	probably_damaging	0,99	neutral	0,29	neutral	4,74	neutral	0,59	neutral	-2,36	low_impact	1,12	neutral	0,74	damaging	0,21	deleterious	3,42	23	0,27	0,45	disease	0,59	disease	0,6	disease	0,51	neutral	0,49	0	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,69	low_impact	-2,59	medium_impact	-0,02	medium_impact	-0,02	0,43	0,8	18,3	19,19	N	0,46	N	0,78	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11531	11531	G	T	MI.17944	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	772	258	A	S	Gcc/Tcc	-1,58	0	0	possibly_damaging	0,62	neutral	0,81	neutral	4,72	neutral	0,94	neutral	-0,89	neutral_impact	0,08	neutral	0,68	neutral	0,91	deleterious	2,04	16,5	0,23	0,45	disease	0,68	neutral	0,14	neutral	0,26	neutral	0,34	3	neutral	0,55	deleterious	0,6	neutral	-3	deleterious	0,72	medium_impact	-0,92	medium_impact	0,56	low_impact	-1,05	0,5	0,8	25,49	20,12	N	0,34	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11531	11531	G	C	MI.17945	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	772	258	A	P	Gcc/Ccc	-1,58	0	0	benign	0,12	neutral	0,21	neutral	4,57	neutral	-2,14	deleterious	-3,02	medium_impact	1,98	neutral	0,72	neutral	0,49	deleterious	3,81	23,4	0,04	0,35	disease	0,89	disease	0,83	disease	0,6	disease	0,77	5	neutral	0,76	deleterious	0,55	neutral	-3	deleterious	0,88	medium_impact	0,1	medium_impact	-0,12	medium_impact	0,83	0,42	0,8	25,49	20,12	N	0,3	N	0,96	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11531	11531	G	A	MI.17946	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	772	258	A	T	Gcc/Acc	-1,58	0	0	benign	0,18	neutral	0,44	neutral	4,65	neutral	0,14	neutral	-1,74	low_impact	1,27	neutral	0,77	neutral	0,61	deleterious	3,12	22,6	0,17	0,45	disease	0,55	neutral	0,41	neutral	0,31	disease	0,6	2	neutral	0,47	deleterious	0,63	neutral	-6	deleterious	0,72	medium_impact	-0,1	medium_impact	0,14	medium_impact	0,13	0,68	0,85	25,49	20,12	N	0,34	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11532	11532	C	G	MI.17947	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	773	258	A	G	gCc/gGc	-0,2	0	0	benign	0,08	neutral	0,42	neutral	4,58	neutral	-1,58	neutral	-2,45	neutral_impact	0,78	neutral	0,79	neutral	0,68	deleterious	2,87	21,7	0,23	0,45	disease	0,76	neutral	0,45	neutral	0,4	disease	0,64	3	neutral	0,53	deleterious	0,67	neutral	-6	deleterious	0,75	medium_impact	0,28	medium_impact	0,12	medium_impact	-0,35	0,54	0,8	25,49	20,12	N	0,31	N	0,65	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11532	11532	C	T	MI.17948	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	773	258	A	V	gCc/gTc	-0,2	0	0	possibly_damaging	0,73	neutral	0,52	neutral	4,61	neutral	-0,62	neutral	-2,07	low_impact	1,4	neutral	0,76	neutral	0,58	deleterious	3,33	22,9	0,13	0,4	neutral	0,5	disease	0,55	neutral	0,45	neutral	0,47	1	neutral	0,7	neutral	0,4	neutral	-3	deleterious	0,73	low_impact	-1,12	medium_impact	0,22	medium_impact	0,26	0,65	0,8	25,49	20,12	N	0,33	N	0,82	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11532	11532	C	A	MI.17949	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	773	258	A	D	gCc/gAc	-0,2	0	0	possibly_damaging	0,9	neutral	0,2	neutral	4,59	neutral	-1,12	deleterious	-3,36	medium_impact	2,19	neutral	0,79	neutral	0,4	deleterious	4,66	24,5	0,05	0,35	disease	0,93	disease	0,8	disease	0,61	disease	0,8	6	neutral	0,94	neutral	0,15	NA	0	deleterious	0,85	low_impact	-1,61	medium_impact	-0,14	medium_impact	1,04	0,15	0,8	25,49	20,12	N	0,32	N	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8531	8531	A	T	MI.1795	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	166	56	T	S	Acg/Tcg	6,84	1	0	possibly_damaging	0,9	neutral	0,4	neutral	0,88	deleterious	-4,36	deleterious	-3,68	high_impact	3,52	neutral	0,99	neutral	0,46	deleterious	3,71	23,3	0,44721401	0,85	neutral	0,46	neutral	0,36	disease	0,71	neutral	0,26	5	neutral	0,9	neutral	0,25	deleterious	1	deleterious	0,72	low_impact	-1,66	medium_impact	0,19	medium_impact	1,92	0,66	0,85	19,12	8,91	P	0,71	P	0,75	disease_causing	0,98	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11534	11534	T	G	MI.17950	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	775	259	Y	D	Tac/Gac	-9,41	0	0	probably_damaging	1	neutral	0,05	neutral	4,52	neutral	-2,07	deleterious	-9,2	medium_impact	2,9	neutral	0,68	damaging	0,11	deleterious	4,03	23,6	0,06	0,35	disease	0,9	disease	0,88	disease	0,77	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,74	0,18	0,8	47,71	9,23	N	0,37	N	0,99	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11534	11534	T	A	MI.17951	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	775	259	Y	N	Tac/Aac	-9,41	0	0	probably_damaging	1	neutral	0,12	neutral	4,63	neutral	-0,15	deleterious	-8,3	medium_impact	2,33	neutral	0,73	damaging	0,14	deleterious	4,06	23,7	0,12	0,4	disease	0,83	disease	0,84	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,28	medium_impact	1,18	0,16	0,8	47,71	9,23	N	0,3	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11534	11534	T	C	MI.17952	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	775	259	Y	H	Tac/Cac	-9,41	0	0	probably_damaging	1	neutral	0,11	neutral	4,51	neutral	-2,22	deleterious	-4,62	medium_impact	2,83	neutral	0,72	damaging	0,12	deleterious	3,61	23,2	0,18	0,45	disease	0,85	disease	0,82	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	-0,31	medium_impact	1,67	0,24	0,8	47,71	9,23	N	0,27	N	0,97	polymorphism	1	0,06	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	11535	11535	A	G	MI.17953	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	776	259	Y	C	tAc/tGc	4,4	0,99	0	probably_damaging	1	neutral	0,07	neutral	4,48	deleterious	-4,08	deleterious	-8,27	medium_impact	3	neutral	0,75	damaging	0,1	deleterious	4,11	23,7	0,06	0,35	disease	0,73	disease	0,87	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,43	medium_impact	1,84	0,09	0,8	47,71	9,23	N	0,5	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11535	11535	A	T	MI.17954	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	776	259	Y	F	tAc/tTc	4,4	0,99	0	probably_damaging	1	neutral	0,26	neutral	4,5	neutral	-2,88	deleterious	-3,56	low_impact	1,4	neutral	0,77	damaging	0,27	deleterious	3,94	23,5	0,3	0,45	disease	0,64	disease	0,66	neutral	0,49	neutral	0,42	2	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,75	low_impact	-3,54	medium_impact	-0,05	medium_impact	0,26	0,32	0,8	47,71	9,23	N	0,52	P	0,79	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11535	11535	A	C	MI.17955	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	776	259	Y	S	tAc/tCc	4,4	0,99	0	probably_damaging	1	neutral	0,18	neutral	4,59	neutral	-0,53	deleterious	-8,27	low_impact	1,7	neutral	0,7	damaging	0,15	deleterious	4,26	23,9	0,09	0,35	disease	0,63	disease	0,8	disease	0,67	disease	0,56	1	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,79	low_impact	-3,54	medium_impact	-0,17	medium_impact	0,56	0,18	0,8	47,71	9,23	N	0,48	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11537	11537	C	A	MI.17956	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	778	260	P	T	Ccc/Acc	-2,5	0	0	probably_damaging	1	neutral	0,39	neutral	4,66	neutral	0,36	deleterious	-7,46	medium_impact	3,03	damaging	0,48	damaging	0,08	deleterious	3,83	23,4	0,13	0,4	neutral	0,5	disease	0,82	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,09	medium_impact	1,87	0,59	0,8	47,06	9,39	N	0,3	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11537	11537	C	G	MI.17957	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	778	260	P	A	Ccc/Gcc	-2,5	0	0	probably_damaging	1	neutral	0,51	neutral	4,67	neutral	0,71	deleterious	-7,46	medium_impact	3,29	damaging	0,52	damaging	0,11	deleterious	3,08	22,5	0,13	0,4	neutral	0,47	disease	0,69	disease	0,67	disease	0,56	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,21	high_impact	2,13	0,64	0,8	47,06	9,39	N	0,29	N	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11537	11537	C	T	MI.17958	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	778	260	P	S	Ccc/Tcc	-2,5	0	0	probably_damaging	1	neutral	0,4	neutral	4,64	neutral	-0,01	deleterious	-7,46	medium_impact	2,77	damaging	0,52	damaging	0,09	deleterious	3,86	23,5	0,14	0,4	neutral	0,44	disease	0,8	disease	0,66	disease	0,58	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,1	medium_impact	1,61	0,32	0,8	47,06	9,39	N	0,23	N	0,71	polymorphism	1	0,07	rs879001835	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11538	11538	C	T	MI.17959	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	779	260	P	L	cCc/cTc	4,4	0,99	0	probably_damaging	1	neutral	0,68	neutral	4,84	neutral	2,5	deleterious	-9,32	medium_impact	2,17	damaging	0,47	damaging	0,1	deleterious	4,46	24,2	0,1	0,4	disease	0,64	disease	0,85	disease	0,51	neutral	0,38	3	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	0,39	medium_impact	1,02	0,55	0,8	47,06	9,39	N	0,45	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8531	8531	A	C	MI.1796	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	166	56	T	P	Acg/Ccg	6,84	1	0	probably_damaging	0,96	neutral	0,31	neutral	0,83	deleterious	-6,14	deleterious	-5,57	medium_impact	2,98	neutral	0,98	neutral	0,56	deleterious	3,61	23,2	0,20425263	0,85	disease	0,73	disease	0,6	disease	0,69	disease	0,63	3	neutral	0,97	neutral	0,18	deleterious	1	deleterious	0,82	low_impact	-2,07	medium_impact	0,1	medium_impact	1,46	0,53	0,85	19,12	8,91	P	0,67	P	0,89	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11538	11538	C	A	MI.17960	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	779	260	P	H	cCc/cAc	4,4	0,99	0	probably_damaging	1	neutral	0,53	neutral	4,61	neutral	-1,51	deleterious	-8,39	high_impact	4,18	damaging	0,53	damaging	0,05	deleterious	4,09	23,7	0,06	0,35	disease	0,81	disease	0,87	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,54	medium_impact	0,23	high_impact	3,01	0,44	0,8	47,06	9,39	P	0,61	P	0,7	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11538	11538	C	G	MI.17961	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	779	260	P	R	cCc/cGc	4,4	0,99	0	probably_damaging	1	neutral	0,34	neutral	4,62	neutral	-0,97	deleterious	-8,39	high_impact	4,18	damaging	0,47	damaging	0,05	deleterious	3,66	23,2	0,05	0,35	disease	0,75	disease	0,91	disease	0,78	disease	0,75	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	0,04	high_impact	3,01	0,55	0,8	47,06	9,39	P	0,66	P	0,58	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11540	11540	T	A	MI.17962	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	781	261	F	I	Ttc/Atc	-6,88	0	0	probably_damaging	0,91	neutral	0,42	neutral	4,82	neutral	1,31	deleterious	-5,44	low_impact	1,4	neutral	0,78	neutral	0,66	deleterious	4,4	24,1	0,12	0,4	neutral	0,38	disease	0,82	neutral	0,46	neutral	0,36	3	neutral	0,91	neutral	0,26	neutral	-2	deleterious	0,73	low_impact	-1,66	medium_impact	0,12	medium_impact	0,26	0,55	0,8	47,93	9,59	N	0,33	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11540	11540	T	C	MI.17963	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	781	261	F	L	Ttc/Ctc	-6,88	0	0	possibly_damaging	0,8	neutral	0,57	neutral	4,93	neutral	1,83	deleterious	-5,47	neutral_impact	0,44	neutral	0,74	neutral	0,63	deleterious	4,05	23,7	0,17	0,45	neutral	0,44	disease	0,76	neutral	0,47	neutral	0,37	3	neutral	0,78	neutral	0,39	neutral	-3	deleterious	0,73	low_impact	-1,28	medium_impact	0,27	medium_impact	-0,69	0,69	0,85	47,93	9,59	N	0,34	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11540	11540	T	G	MI.17964	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	781	261	F	V	Ttc/Gtc	-6,88	0	0	possibly_damaging	0,88	neutral	0,1	neutral	4,69	neutral	0,5	deleterious	-6,37	medium_impact	1,99	neutral	0,73	neutral	0,57	deleterious	4,18	23,8	0,1	0,4	disease	0,59	disease	0,88	neutral	0,5	disease	0,54	1	neutral	0,96	neutral	0,11	NA	0	deleterious	0,78	low_impact	-1,53	medium_impact	-0,33	medium_impact	0,84	0,4	0,8	47,93	9,59	N	0,36	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11541	11541	T	G	MI.17965	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	782	261	F	C	tTc/tGc	5,78	1	0	probably_damaging	0,98	deleterious	0	neutral	4,53	deleterious	-3,06	deleterious	-7,35	medium_impact	3,08	neutral	0,75	neutral	0,47	deleterious	4,14	23,8	0,04	0,35	disease	0,67	disease	0,88	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-2,31	low_impact	-1,48	medium_impact	1,92	0,27	0,8	47,93	9,59	P	0,57	P	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11541	11541	T	A	MI.17966	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	782	261	F	Y	tTc/tAc	5,78	1	0	probably_damaging	0,92	deleterious	0,02	neutral	4,54	neutral	-2,25	deleterious	-2,77	medium_impact	2,54	neutral	0,73	neutral	0,53	deleterious	4,27	24	0,13	0,4	disease	0,83	disease	0,81	disease	0,66	disease	0,7	4	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,8	low_impact	-1,71	medium_impact	-0,75	medium_impact	1,39	0,58	0,8	47,93	9,59	P	0,61	P	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11541	11541	T	C	MI.17967	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	782	261	F	S	tTc/tCc	5,78	1	0	benign	0,2	deleterious	0	neutral	4,55	neutral	-1,78	deleterious	-7,37	medium_impact	3,34	neutral	0,71	neutral	0,54	deleterious	4,29	24	0,04	0,35	disease	0,57	disease	0,85	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,79	medium_impact	-0,15	low_impact	-1,48	high_impact	2,18	0,35	0,8	47,93	9,59	P	0,6	P	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11542	11542	C	G	MI.17968	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	783	261	F	L	ttC/ttG	7,4	1	0	possibly_damaging	0,8	neutral	0,57	neutral	4,93	neutral	1,83	deleterious	-5,47	neutral_impact	0,44	neutral	0,74	neutral	0,63	deleterious	4,36	24,1	0,17	0,45	neutral	0,44	disease	0,76	neutral	0,47	neutral	0,37	3	neutral	0,78	neutral	0,39	neutral	-3	deleterious	0,73	low_impact	-1,28	medium_impact	0,27	medium_impact	-0,69	0,69	0,85	47,93	9,59	P	0,5	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11542	11542	C	A	MI.17969	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	783	261	F	L	ttC/ttA	7,4	1	0	possibly_damaging	0,8	neutral	0,57	neutral	4,93	neutral	1,83	deleterious	-5,47	neutral_impact	0,44	neutral	0,74	neutral	0,63	deleterious	4,69	24,6	0,17	0,45	neutral	0,44	disease	0,76	neutral	0,47	neutral	0,37	3	neutral	0,78	neutral	0,39	neutral	-3	deleterious	0,73	low_impact	-1,28	medium_impact	0,27	medium_impact	-0,69	0,69	0,85	47,93	9,59	P	0,5	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8532	8532	C	T	MI.1797	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	167	56	T	M	aCg/aTg	1,75	0,87	0	probably_damaging	0,99	neutral	0,22	neutral	0,81	deleterious	-6,69	deleterious	-5,57	high_impact	3,52	neutral	1	neutral	0,42	deleterious	4,08	23,7	0,38597345	0,85	disease	0,82	neutral	0,42	disease	0,74	neutral	0,34	3	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,82	low_impact	-2,65	medium_impact	-0,02	medium_impact	1,92	0,73	0,85	19,12	8,91	P	0,56	P	0,9	disease_causing	0,5	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11543	11543	C	G	MI.17970	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	784	262	L	V	Ctt/Gtt	-2,96	0	0	benign	0,41	neutral	0,28	neutral	4,55	neutral	-1,17	neutral	-0,21	low_impact	1,01	neutral	0,76	neutral	0,89	neutral	1,53	13,5	0,24	0,45	disease	0,63	disease	0,57	neutral	0,37	neutral	0,27	5	neutral	0,67	neutral	0,44	neutral	-6	neutral	0,27	medium_impact	-0,57	medium_impact	-0,03	medium_impact	-0,13	0,51	0,8	11,76	23,44	N	0,39	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11543	11543	C	T	MI.17971	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	784	262	L	F	Ctt/Ttt	-2,96	0	0	probably_damaging	0,93	neutral	0,11	neutral	4,44	neutral	-2,98	neutral	-2,35	low_impact	1,51	neutral	0,72	neutral	0,7	deleterious	3,63	23,2	0,18	0,45	disease	0,67	disease	0,66	disease	0,58	disease	0,55	1	neutral	0,97	neutral	0,09	neutral	-2	deleterious	0,64	low_impact	-1,77	medium_impact	-0,31	medium_impact	0,37	0,52	0,8	11,76	23,44	N	0,32	N	0,26	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11543	11543	C	A	MI.17972	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	784	262	L	I	Ctt/Att	-2,96	0	0	benign	0,2	neutral	1	neutral	4,55	neutral	-0,85	neutral	0,64	neutral_impact	-0,29	neutral	0,69	neutral	0,99	neutral	-0,5	0,22	0,3	0,45	disease	0,55	neutral	0,1	neutral	0,24	neutral	0,31	4	neutral	0,2	deleterious	0,9	neutral	-6	neutral	0,15	medium_impact	-0,15	high_impact	1,88	low_impact	-1,41	0,38	0,8	11,76	23,44	N	0,32	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11544	11544	T	C	MI.17973	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	785	262	L	P	cTt/cCt	-0,2	0	0	probably_damaging	0,99	deleterious	0	neutral	4,37	deleterious	-4,96	deleterious	-5,07	medium_impact	3,31	neutral	0,6	neutral	0,39	deleterious	3,86	23,5	0,02	0,35	disease	0,91	disease	0,91	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,87	low_impact	-2,59	low_impact	-1,48	high_impact	2,15	0,31	0,8	11,76	23,44	N	0,29	N	0,92	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11544	11544	T	G	MI.17974	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	785	262	L	R	cTt/cGt	-0,2	0	0	probably_damaging	0,98	deleterious	0	neutral	4,37	deleterious	-4,6	deleterious	-4,74	medium_impact	3,31	neutral	0,67	neutral	0,45	deleterious	4,11	23,7	0,02	0,35	disease	0,88	disease	0,93	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,86	low_impact	-2,31	low_impact	-1,48	high_impact	2,15	0,24	0,8	11,76	23,44	N	0,32	N	0,86	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11544	11544	T	A	MI.17975	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	785	262	L	H	cTt/cAt	-0,2	0	0	probably_damaging	0,99	deleterious	0	neutral	4,37	deleterious	-5,18	deleterious	-5,07	medium_impact	3,31	neutral	0,73	neutral	0,51	deleterious	4,03	23,7	0,04	0,35	disease	0,91	disease	0,77	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-2,59	low_impact	-1,48	high_impact	2,15	0,2	0,8	11,76	23,44	N	0,31	N	0,77	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11546	11546	G	T	MI.17976	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	787	263	V	L	Gta/Tta	-5,73	0	0	benign	0,01	neutral	0,39	neutral	4,69	neutral	-1	neutral	-0,04	neutral_impact	-0,26	neutral	0,77	neutral	0,92	deleterious	0,41	6,68	0,13	0,4	neutral	0,43	disease	0,6	neutral	0,32	neutral	0,25	5	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,17	medium_impact	1,16	medium_impact	0,09	low_impact	-1,38	0,42	0,8	24,4	18,58	N	0,32	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11546	11546	G	C	MI.17977	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	787	263	V	L	Gta/Cta	-5,73	0	0	benign	0,01	neutral	0,39	neutral	4,69	neutral	-1	neutral	-0,04	neutral_impact	-0,26	neutral	0,77	neutral	0,92	deleterious	0,25	5,17	0,13	0,4	neutral	0,43	disease	0,6	neutral	0,32	neutral	0,25	5	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,17	medium_impact	1,16	medium_impact	0,09	low_impact	-1,38	0,42	0,8	24,4	18,58	N	0,31	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11546	11546	G	A	MI.17978	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	787	263	V	M	Gta/Ata	-5,73	0	0	benign	0	neutral	0,26	neutral	4,55	deleterious	-3,11	neutral	0,06	neutral_impact	-0,34	neutral	0,73	neutral	0,97	deleterious	0,08	3,36	0,16	0,45	disease	0,61	neutral	0,39	neutral	0,33	disease	0,61	2	neutral	0,74	deleterious	0,63	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	-0,05	low_impact	-1,46	0,58	0,8	24,4	18,58	N	0,41	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11547	11547	T	A	MI.17979	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	788	263	V	E	gTa/gAa	-0,2	0	0	benign	0,1	neutral	0,07	neutral	4,48	deleterious	-4,9	deleterious	-4,35	medium_impact	2,26	neutral	0,73	neutral	0,5	deleterious	2,65	20,5	0,02	0,35	disease	0,87	disease	0,86	disease	0,67	disease	0,74	5	neutral	0,92	deleterious	0,49	neutral	-3	neutral	0,33	medium_impact	0,18	medium_impact	-0,43	medium_impact	1,11	0,2	0,8	24,4	18,58	N	0,31	N	0,33	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8532	8532	C	A	MI.1798	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	167	56	T	K	aCg/aAg	1,75	0,87	0	probably_damaging	0,96	neutral	0,38	neutral	0,84	deleterious	-5,43	deleterious	-5,3	high_impact	3,52	neutral	0,99	neutral	0,36	deleterious	4,56	24,4	0,22335685	0,85	disease	0,69	disease	0,56	disease	0,7	disease	0,65	3	neutral	0,96	neutral	0,21	deleterious	2	deleterious	0,82	low_impact	-2,07	medium_impact	0,17	medium_impact	1,92	0,62	0,85	19,12	8,91	N	0,53	P	0,91	disease_causing	0,65	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11547	11547	T	G	MI.17980	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	788	263	V	G	gTa/gGa	-0,2	0	0	benign	0,06	neutral	0,17	neutral	4,51	neutral	-2,84	deleterious	-5,25	neutral_impact	0,72	neutral	0,73	neutral	0,55	deleterious	1,8	15	0,04	0,35	disease	0,79	disease	0,66	disease	0,54	neutral	0,39	2	neutral	0,82	deleterious	0,56	neutral	-6	neutral	0,24	medium_impact	0,41	medium_impact	-0,18	medium_impact	-0,41	0,31	0,8	24,4	18,58	N	0,26	N	0,36	polymorphism	1	0,08	rs28588421	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11547	11547	T	C	MI.17981	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	788	263	V	A	gTa/gCa	-0,2	0	0	benign	0	neutral	0,34	neutral	4,58	neutral	-1,12	deleterious	-2,71	neutral_impact	-0,4	neutral	0,74	neutral	0,92	deleterious	0,44	6,97	0,1	0,4	neutral	0,38	neutral	0,44	neutral	0,36	neutral	0,44	1	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,13	high_impact	2,1	medium_impact	0,04	low_impact	-1,52	0,16	0,8	24,4	18,58	N	0,4	N	0,04	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11549	11549	C	A	MI.17982	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	790	264	L	M	Cta/Ata	-3,89	0	0	probably_damaging	1	deleterious	0,03	neutral	4,35	deleterious	-3,07	neutral	-1,73	medium_impact	2,58	neutral	0,74	neutral	0,28	deleterious	3,67	23,3	0,2	0,45	disease	0,54	disease	0,55	neutral	0,44	neutral	0,21	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,72	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,43	0,45	0,8	46,19	9,24	N	0,34	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11549	11549	C	G	MI.17983	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	790	264	L	V	Cta/Gta	-3,89	0	0	probably_damaging	1	neutral	0,2	neutral	4,51	neutral	-1,51	deleterious	-2,72	medium_impact	2,18	neutral	0,73	damaging	0,25	deleterious	3,42	23	0,19	0,45	disease	0,68	disease	0,66	disease	0,64	neutral	0,49	0	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,14	medium_impact	1,03	0,51	0,8	46,19	9,24	N	0,28	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11550	11550	T	G	MI.17984	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	791	264	L	R	cTa/cGa	-2,73	0	0	probably_damaging	1	deleterious	0	neutral	4,31	deleterious	-5,49	deleterious	-5,51	high_impact	4,25	neutral	0,61	damaging	0,13	deleterious	4,17	23,8	0,03	0,35	disease	0,94	disease	0,92	disease	0,76	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,54	low_impact	-1,48	high_impact	3,08	0,19	0,8	46,19	9,24	N	0,37	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11550	11550	T	A	MI.17985	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	791	264	L	Q	cTa/cAa	-2,73	0	0	probably_damaging	1	deleterious	0	neutral	4,31	deleterious	-5,56	deleterious	-5,48	high_impact	4,25	neutral	0,69	damaging	0,16	deleterious	4,27	24	0,03	0,35	disease	0,94	disease	0,82	disease	0,65	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,08	0,31	0,8	46,19	9,24	N	0,33	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11550	11550	T	C	MI.17986	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	791	264	L	P	cTa/cCa	-2,73	0	0	probably_damaging	1	deleterious	0	neutral	4,3	deleterious	-5,67	deleterious	-6,43	high_impact	3,9	damaging	0,59	damaging	0,14	deleterious	4,01	23,6	0,03	0,35	disease	0,95	disease	0,86	disease	0,76	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	2,73	0,38	0,8	46,19	9,24	N	0,33	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11552	11552	T	C	MI.17987	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	793	265	S	P	Tcc/Ccc	-5,96	0	0	probably_damaging	0,97	deleterious	0,03	neutral	4,44	deleterious	-3,36	deleterious	-3,71	high_impact	3,99	neutral	0,64	damaging	0,11	deleterious	3,94	23,5	0,03	0,35	disease	0,84	disease	0,92	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,89	low_impact	-2,14	medium_impact	-0,64	high_impact	2,82	0,31	0,8	40,31	8,51	N	0,37	N	0,99	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11552	11552	T	A	MI.17988	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	793	265	S	T	Tcc/Acc	-5,96	0	0	possibly_damaging	0,74	neutral	0,09	neutral	4,48	neutral	-0,83	neutral	-2,14	medium_impact	2,54	neutral	0,67	damaging	0,14	deleterious	3,78	23,4	0,11	0,4	disease	0,54	disease	0,68	disease	0,63	disease	0,69	4	neutral	0,93	neutral	0,18	NA	0	deleterious	0,75	low_impact	-1,14	medium_impact	-0,36	medium_impact	1,39	0,51	0,8	40,31	8,51	N	0,32	N	0,73	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11552	11552	T	G	MI.17989	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	793	265	S	A	Tcc/Gcc	-5,96	0	0	benign	0,08	neutral	0,85	neutral	4,65	neutral	1,46	neutral	-0,89	neutral_impact	0,42	neutral	0,62	neutral	0,47	neutral	0,94	10,29	0,12	0,4	neutral	0,4	neutral	0,14	neutral	0,32	neutral	0,23	5	neutral	0,06	deleterious	0,89	neutral	-6	deleterious	0,66	medium_impact	0,28	medium_impact	0,62	medium_impact	-0,71	0,33	0,8	40,31	8,51	N	0,34	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8534	8534	A	C	MI.1799	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	169	57	K	Q	Aaa/Caa	-0,1	0,06	0	probably_damaging	0,96	neutral	0,45	neutral	0,7	deleterious	-5,01	deleterious	-3,72	high_impact	3,52	neutral	0,8	damaging	0,09	deleterious	3,42	23	0,42430023	0,85	disease	0,66	disease	0,54	disease	0,75	disease	0,66	3	neutral	0,96	neutral	0,25	deleterious	2	deleterious	0,79	low_impact	-2,07	medium_impact	0,24	medium_impact	1,92	0,74	0,85	20,59	8,73	N	0,3	N	0,8	polymorphism	0,99	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11553	11553	C	T	MI.17990	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	794	265	S	F	tCc/tTc	2,79	0,99	0	probably_damaging	0,97	neutral	0,06	neutral	4,46	neutral	-2,33	deleterious	-4,61	medium_impact	3,02	damaging	0,6	damaging	0,11	deleterious	4,22	23,9	0,03	0,35	neutral	0,44	disease	0,9	disease	0,66	disease	0,76	5	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,79	low_impact	-2,14	medium_impact	-0,47	medium_impact	1,86	0,09	0,8	40,31	8,51	N	0,46	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11553	11553	C	A	MI.17991	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	794	265	S	Y	tCc/tAc	2,79	0,99	0	probably_damaging	0,98	neutral	0,05	neutral	4,45	neutral	-2,88	deleterious	-4,61	high_impact	3,64	neutral	0,66	damaging	0,1	deleterious	4,19	23,9	0,03	0,35	disease	0,69	disease	0,88	disease	0,66	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,83	low_impact	-2,31	medium_impact	-0,52	high_impact	2,48	0,22	0,8	40,31	8,51	P	0,52	P	1	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11553	11553	C	G	MI.17992	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	794	265	S	C	tCc/tGc	2,79	0,99	0	probably_damaging	0,98	neutral	0,21	neutral	4,45	neutral	-2,9	deleterious	-3,21	medium_impact	2,19	neutral	0,62	damaging	0,26	deleterious	2,48	19,34	0,03	0,35	disease	0,76	disease	0,82	neutral	0,44	neutral	0,28	4	deleterious	0,98	neutral	0,12	deleterious	1	deleterious	0,78	low_impact	-2,31	medium_impact	-0,12	medium_impact	1,04	0,26	0,8	40,31	8,51	N	0,45	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11555	11555	C	G	MI.17993	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	796	266	L	V	Cta/Gta	-8,26	0	0	probably_damaging	1	neutral	0,11	neutral	4,66	neutral	-0,18	neutral	-2,36	medium_impact	2,25	neutral	0,68	damaging	0,18	deleterious	3,45	23	0,34	0,5	disease	0,67	disease	0,67	disease	0,61	disease	0,63	3	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,31	medium_impact	1,1	0,38	0,8	18,74	11,36	N	0,28	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11555	11555	C	A	MI.17994	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	796	266	L	M	Cta/Ata	-8,26	0	0	probably_damaging	1	neutral	0,08	neutral	4,49	neutral	-2,89	neutral	-1,42	medium_impact	2,46	neutral	0,78	neutral	0,82	deleterious	2,68	20,7	0,26	0,45	disease	0,77	neutral	0,48	neutral	0,41	neutral	0,47	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	-0,39	medium_impact	1,31	0,48	0,8	18,74	11,36	N	0,4	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11556	11556	T	C	MI.17995	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	797	266	L	P	cTa/cCa	-1,81	0	0	probably_damaging	1	deleterious	0	neutral	4,46	deleterious	-5,01	deleterious	-6,03	high_impact	4,42	damaging	0,57	damaging	0,1	deleterious	3,93	23,5	0,03	0,35	disease	0,97	disease	0,82	disease	0,74	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	3,25	0,28	0,8	18,74	11,36	N	0,39	N	0,98	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11556	11556	T	G	MI.17996	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	797	266	L	R	cTa/cGa	-1,81	0	0	probably_damaging	1	deleterious	0,02	neutral	4,47	deleterious	-4,62	deleterious	-5,17	high_impact	4,42	neutral	0,61	damaging	0,1	deleterious	4,22	23,9	0,03	0,35	disease	0,95	disease	0,9	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,91	low_impact	-3,54	medium_impact	-0,75	high_impact	3,25	0,12	0,8	18,74	11,36	N	0,42	N	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11556	11556	T	A	MI.17997	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	797	266	L	Q	cTa/cAa	-1,81	0	0	probably_damaging	1	deleterious	0	neutral	4,46	deleterious	-4,8	deleterious	-5,11	high_impact	4,42	damaging	0,6	damaging	0,11	deleterious	4,09	23,7	0,05	0,35	disease	0,96	disease	0,78	disease	0,62	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,25	0,2	0,8	18,74	11,36	N	0,36	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11558	11558	T	C	MI.17998	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	799	267	W	R	Tga/Cga	0,03	0,97	0	probably_damaging	1	deleterious	0,02	neutral	4,61	neutral	-1,71	deleterious	-13,07	high_impact	3,83	damaging	0,45	damaging	0,05	deleterious	3,59	23,2	0,06	0,35	disease	0,79	disease	0,92	disease	0,81	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,54	medium_impact	-0,75	high_impact	2,66	0,11	0,8	46,19	9,33	P	0,56	P	0,97	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11558	11558	T	G	MI.17999	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	799	267	W	G	Tga/Gga	0,03	0,97	0	probably_damaging	1	deleterious	0,02	neutral	4,61	neutral	0,06	deleterious	-12,13	medium_impact	3,08	damaging	0,48	damaging	0,08	deleterious	3,91	23,5	0,08	0,35	neutral	0,42	disease	0,87	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,92	0,09	0,8	46,19	9,33	N	0,49	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8534	8534	A	G	MI.18	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	8	3	E	G	gAa/gGa	-0,1	0,06	0	probably_damaging	0,97	neutral	0,37	neutral	4,62	neutral	-1,22	deleterious	-3,74	low_impact	1,61	neutral	0,83	neutral	0,59	deleterious	4,02	23,6	0,68	0,75	neutral	0,26	neutral	0,14	neutral	0,3	neutral	0,35	3	neutral	0,97	neutral	0,2	neutral	-2	deleterious	0,61	low_impact	-2,19	medium_impact	0,16	medium_impact	0,28	0,64	0,9	15,93	14,48	N	0,38	N	0,64	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8609	8609	C	T	MI.180	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	83	28	P	L	cCt/cTt	-0,57	0	0	possibly_damaging	0,52	neutral	1	neutral	4,61	neutral	3,81	neutral	-0,12	neutral_impact	-0,76	neutral	0,9	neutral	0,77	deleterious	0,72	8,94	0,45	0,65	neutral	0,29	neutral	0,26	neutral	0,11	neutral	0,43	1	neutral	0,52	deleterious	0,74	neutral	-3	neutral	0,39	medium_impact	-0,79	high_impact	1,98	low_impact	-1,75	0,78	0,9	31,86	20,94	N	0,35	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8534	8534	A	G	MI.1800	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	169	57	K	E	Aaa/Gaa	-0,1	0,06	0	possibly_damaging	0,9	neutral	0,82	neutral	0,71	deleterious	-4,91	deleterious	-3,72	high_impact	3,52	damaging	0,56	damaging	0,09	deleterious	4,02	23,6	0,44721401	0,85	disease	0,66	disease	0,51	disease	0,75	disease	0,67	3	neutral	0,88	neutral	0,46	deleterious	1	deleterious	0,79	low_impact	-1,66	medium_impact	0,66	medium_impact	1,92	0,63	0,85	20,59	8,73	N	0,32	N	0,86	polymorphism	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11559	11559	G	T	MI.18000	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	800	267	W	L	tGa/tTa	7,4	1	0	probably_damaging	1	neutral	0,32	neutral	4,93	neutral	2,46	deleterious	-12,13	medium_impact	2,02	damaging	0,46	damaging	0,07	deleterious	4,26	23,9	0,11	0,4	neutral	0,43	disease	0,85	disease	0,72	neutral	0,43	1	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,02	medium_impact	0,87	0,08	0,8	46,19	9,33	P	0,52	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11559	11559	G	C	MI.18001	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	800	267	W	S	tGa/tCa	7,4	1	0	probably_damaging	1	deleterious	0,04	neutral	4,63	neutral	-0,37	deleterious	-13,06	high_impact	3,83	damaging	0,44	damaging	0,08	deleterious	4,05	23,7	0,09	0,35	disease	0,54	disease	0,91	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-3,54	medium_impact	-0,57	high_impact	2,66	0,07	0,8	46,19	9,33	P	0,62	P	0,93	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11560	11560	A	T	MI.18002	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	801	267	W	C	tgA/tgT	7,4	1	0,01	probably_damaging	1	deleterious	0,02	neutral	4,61	neutral	-1,38	deleterious	-12,14	medium_impact	3,28	damaging	0,46	damaging	0,04	deleterious	4,12	23,8	0,09	0,35	disease	0,52	disease	0,91	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-3,54	medium_impact	-0,75	high_impact	2,12	0,1	0,8	46,19	9,33	P	0,61	P	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11560	11560	A	C	MI.18003	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	801	267	W	C	tgA/tgC	7,4	1	0,01	probably_damaging	1	deleterious	0,02	neutral	4,61	neutral	-1,38	deleterious	-12,14	medium_impact	3,28	damaging	0,46	damaging	0,04	deleterious	4,04	23,7	0,09	0,35	disease	0,52	disease	0,91	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-3,54	medium_impact	-0,75	high_impact	2,12	0,1	0,8	46,19	9,33	P	0,61	P	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11561	11561	G	A	MI.18004	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	802	268	G	S	Ggc/Agc	0,95	1	0	possibly_damaging	0,7	deleterious	0,04	neutral	4,87	neutral	0,03	deleterious	-5,63	medium_impact	2,64	damaging	0,49	neutral	0,32	deleterious	4,18	23,8	0,13	0,4	neutral	0,39	disease	0,8	disease	0,61	disease	0,66	3	neutral	0,97	neutral	0,17	deleterious	4	deleterious	0,77	low_impact	-1,06	medium_impact	-0,57	medium_impact	1,49	0,58	0,8	46,41	9,38	N	0,48	N	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11561	11561	G	T	MI.18005	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	802	268	G	C	Ggc/Tgc	0,95	1	0	probably_damaging	1	deleterious	0	neutral	4,5	deleterious	-4,78	deleterious	-8,45	high_impact	4,01	damaging	0,52	damaging	0,19	deleterious	4,23	23,9	0,05	0,35	disease	0,68	disease	0,88	disease	0,68	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,84	0,09	0,8	46,41	9,38	P	0,5	N	0,98	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11561	11561	G	C	MI.18006	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	802	268	G	R	Ggc/Cgc	0,95	1	0	probably_damaging	0,99	deleterious	0	neutral	4,54	neutral	-2,98	deleterious	-7,51	high_impact	4,56	damaging	0,53	damaging	0,2	deleterious	4	23,6	0,04	0,35	disease	0,82	disease	0,89	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,59	low_impact	-1,48	high_impact	3,39	0,28	0,8	46,41	9,38	P	0,59	P	1	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11562	11562	G	C	MI.18007	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	803	268	G	A	gGc/gCc	6,01	1	0	probably_damaging	0,92	neutral	0,07	neutral	4,59	neutral	-0,91	deleterious	-5,63	medium_impact	2,78	damaging	0,56	neutral	0,36	deleterious	3,15	22,6	0,13	0,4	neutral	0,39	disease	0,7	disease	0,65	disease	0,66	3	deleterious	0,98	neutral	0,08	deleterious	1	deleterious	0,76	low_impact	-1,71	medium_impact	-0,43	medium_impact	1,62	0,3	0,8	46,41	9,38	P	0,61	P	0,76	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11562	11562	G	A	MI.18008	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	803	268	G	D	gGc/gAc	6,01	1	0	probably_damaging	0,98	deleterious	0	neutral	4,54	deleterious	-3,18	deleterious	-6,57	high_impact	4,56	damaging	0,57	damaging	0,24	deleterious	3,87	23,5	0,04	0,35	disease	0,9	disease	0,87	disease	0,77	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,31	low_impact	-1,48	high_impact	3,39	0,09	0,8	46,41	9,38	P	0,69	P	0,99	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11562	11562	G	T	MI.18009	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	803	268	G	V	gGc/gTc	6,01	1	0	probably_damaging	0,98	deleterious	0	neutral	4,53	neutral	-2,74	deleterious	-8,45	high_impact	4,01	damaging	0,49	damaging	0,26	deleterious	3,8	23,4	0,04	0,35	neutral	0,39	disease	0,88	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,31	low_impact	-1,48	high_impact	2,84	0,08	0,8	46,41	9,38	P	0,61	P	0,98	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8535	8535	A	C	MI.1801	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	170	57	K	T	aAa/aCa	4,06	1	0	probably_damaging	0,94	neutral	0,44	neutral	0,68	deleterious	-5,6	deleterious	-5,58	high_impact	3,52	neutral	0,78	damaging	0,09	deleterious	3,66	23,2	0,30143898	0,85	disease	0,75	disease	0,54	disease	0,75	disease	0,66	3	neutral	0,93	neutral	0,25	deleterious	2	deleterious	0,83	low_impact	-1,89	medium_impact	0,23	medium_impact	1,92	0,54	0,85	20,59	8,73	N	0,53	P	0,81	disease_causing	0,62	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11564	11564	A	T	MI.18010	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	805	269	M	L	Ata/Tta	-20	0	0	probably_damaging	0,98	neutral	0,53	neutral	4,67	neutral	0,14	neutral	-1,65	low_impact	1,84	damaging	0,54	damaging	0,14	deleterious	3,31	22,9	0,18	0,45	disease	0,56	disease	0,6	neutral	0,41	neutral	0,27	5	deleterious	0,98	neutral	0,28	neutral	-2	deleterious	0,56	low_impact	-2,31	medium_impact	0,23	medium_impact	0,69	0,12	0,8	46,84	9,04	N	0,28	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11564	11564	A	C	MI.18011	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	805	269	M	L	Ata/Cta	-20	0	0	probably_damaging	0,98	neutral	0,53	neutral	4,67	neutral	0,14	neutral	-1,65	low_impact	1,84	damaging	0,54	damaging	0,14	deleterious	3,2	22,7	0,18	0,45	disease	0,56	disease	0,6	neutral	0,41	neutral	0,27	5	deleterious	0,98	neutral	0,28	neutral	-2	deleterious	0,56	low_impact	-2,31	medium_impact	0,23	medium_impact	0,69	0,12	0,8	46,84	9,04	N	0,27	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11564	11564	A	G	MI.18012	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	805	269	M	V	Ata/Gta	-20	0	0	probably_damaging	0,99	neutral	0,97	neutral	4,64	neutral	-0,53	neutral	-1,77	low_impact	1,22	neutral	0,65	neutral	0,3	neutral	0,92	10,21	0,21	0,45	neutral	0,4	neutral	0,31	neutral	0,36	neutral	0,45	1	deleterious	0,99	deleterious	0,49	neutral	-2	deleterious	0,56	low_impact	-2,59	medium_impact	1,05	medium_impact	0,08	0,12	0,8	46,84	9,04	N	0,23	N	0,96	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11565	11565	T	C	MI.18013	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	806	269	M	T	aTa/aCa	3,25	0,98	0	probably_damaging	1	neutral	0,15	neutral	4,52	neutral	-1,73	deleterious	-4,27	medium_impact	2,01	damaging	0,45	damaging	0,17	deleterious	2,96	22,1	0,09	0,35	neutral	0,37	disease	0,55	disease	0,53	neutral	0,45	1	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,67	low_impact	-3,54	medium_impact	-0,22	medium_impact	0,86	0,04	0,8	46,84	9,04	P	0,59	P	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11565	11565	T	A	MI.18014	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	806	269	M	K	aTa/aAa	3,25	0,98	0	probably_damaging	1	neutral	0,09	neutral	4,46	deleterious	-3,93	deleterious	-4,9	medium_impact	3,33	damaging	0,45	damaging	0,06	deleterious	3,98	23,6	0,04	0,35	disease	0,78	disease	0,8	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,36	high_impact	2,17	0,1	0,8	46,84	9,04	P	0,56	P	1	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11566	11566	A	T	MI.18015	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	807	269	M	I	atA/atT	2,79	0,98	0	probably_damaging	0,99	neutral	1	neutral	4,68	neutral	0,64	neutral	-1,65	neutral_impact	0,34	neutral	0,64	neutral	0,34	neutral	1,36	12,56	0,2	0,45	disease	0,58	neutral	0,32	neutral	0,32	disease	0,6	2	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,64	low_impact	-2,59	high_impact	1,88	medium_impact	-0,79	0,17	0,8	46,84	9,04	N	0,42	N	0,95	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11566	11566	A	C	MI.18016	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	807	269	M	I	atA/atC	2,79	0,98	0	probably_damaging	0,99	neutral	1	neutral	4,68	neutral	0,64	neutral	-1,65	neutral_impact	0,34	neutral	0,64	neutral	0,34	neutral	1,3	12,27	0,2	0,45	disease	0,58	neutral	0,32	neutral	0,32	disease	0,6	2	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,64	low_impact	-2,59	high_impact	1,88	medium_impact	-0,79	0,17	0,8	46,84	9,04	N	0,4	N	0,95	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11567	11567	A	G	MI.18017	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	808	270	I	V	Att/Gtt	-1,81	0	0	benign	0,08	neutral	0,85	neutral	4,37	neutral	-1,65	neutral	-0,42	neutral_impact	0,62	neutral	0,78	neutral	0,94	neutral	-0,23	0,95	0,37	0,5	disease	0,61	neutral	0,12	neutral	0,33	neutral	0,31	4	neutral	0,06	deleterious	0,89	neutral	-6	neutral	0,12	medium_impact	0,28	medium_impact	0,62	medium_impact	-0,51	0,39	0,8	15,69	12,56	N	0,27	N	0,75	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11567	11567	A	T	MI.18018	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	808	270	I	F	Att/Ttt	-1,81	0	0	probably_damaging	0,96	neutral	0,25	neutral	4,41	neutral	-1,22	deleterious	-3,53	low_impact	1,84	neutral	0,69	neutral	0,47	deleterious	3,51	23,1	0,12	0,4	disease	0,76	disease	0,61	disease	0,53	neutral	0,3	4	neutral	0,97	neutral	0,15	neutral	-2	deleterious	0,62	low_impact	-2,01	medium_impact	-0,07	medium_impact	0,69	0,34	0,8	15,69	12,56	N	0,32	N	0,96	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11567	11567	A	C	MI.18019	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	808	270	I	L	Att/Ctt	-1,81	0	0	possibly_damaging	0,52	neutral	0,63	neutral	4,89	neutral	0,79	neutral	-1,5	low_impact	0,86	neutral	0,73	neutral	0,81	deleterious	1,89	15,51	0,22	0,45	disease	0,51	neutral	0,31	neutral	0,33	neutral	0,34	3	neutral	0,44	deleterious	0,56	neutral	-3	neutral	0,17	medium_impact	-0,75	medium_impact	0,33	medium_impact	-0,28	0,3	0,8	15,69	12,56	N	0,32	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8535	8535	A	T	MI.1802	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	170	57	K	M	aAa/aTa	4,06	1	0	probably_damaging	0,99	neutral	0,08	neutral	0,66	deleterious	-7,2	deleterious	-5,58	high_impact	3,52	neutral	0,8	damaging	0,09	deleterious	4,02	23,6	0,24042424	0,85	disease	0,89	neutral	0,39	disease	0,76	neutral	0,36	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,83	low_impact	-2,65	medium_impact	-0,31	medium_impact	1,92	0,59	0,85	20,59	8,73	P	0,55	P	0,69	disease_causing	0,79	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11568	11568	T	A	MI.18020	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	809	270	I	N	aTt/aAt	0,26	0,01	0	probably_damaging	0,98	deleterious	0	neutral	4,22	deleterious	-6,55	deleterious	-6,03	high_impact	3,55	neutral	0,68	neutral	0,45	deleterious	4,44	24,2	0,07	0,35	disease	0,59	disease	0,75	disease	0,62	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,67	low_impact	-2,31	low_impact	-1,48	high_impact	2,39	0,28	0,8	15,69	12,56	N	0,34	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11568	11568	T	G	MI.18021	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	809	270	I	S	aTt/aGt	0,26	0,01	0	probably_damaging	0,94	deleterious	0	neutral	4,23	deleterious	-5,38	deleterious	-5,08	medium_impact	2,54	neutral	0,71	neutral	0,46	deleterious	3,93	23,5	0,04	0,35	neutral	0,36	disease	0,76	disease	0,61	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,49	low_impact	-1,84	low_impact	-1,48	medium_impact	1,39	0,17	0,8	15,69	12,56	N	0,36	N	0,95	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11568	11568	T	C	MI.18022	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	809	270	I	T	aTt/aCt	0,26	0,01	0	possibly_damaging	0,83	deleterious	0,03	neutral	4,23	deleterious	-4,63	deleterious	-3,9	medium_impact	2,52	neutral	0,79	neutral	0,61	neutral	1,75	14,72	0,08	0,35	neutral	0,45	disease	0,54	disease	0,59	disease	0,58	2	deleterious	0,98	neutral	0,1	deleterious	4	neutral	0,42	low_impact	-1,37	medium_impact	-0,64	medium_impact	1,37	0,2	0,8	15,69	12,56	N	0,4	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11569	11569	T	G	MI.18023	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	810	270	I	M	atT/atG	7,4	0,96	0	probably_damaging	0,96	deleterious	0,04	neutral	4,29	neutral	-2,79	neutral	-2,23	medium_impact	2,52	neutral	0,74	neutral	0,53	deleterious	3,24	22,8	0,21	0,45	disease	0,8	neutral	0,48	disease	0,51	disease	0,6	2	deleterious	0,99	neutral	0,04	deleterious	5	deleterious	0,61	low_impact	-2,01	medium_impact	-0,57	medium_impact	1,37	0,3	0,8	15,69	12,56	P	0,59	P	0,76	polymorphism	1	0,03	rs386829133	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11569	11569	T	A	MI.18024	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	810	270	I	M	atT/atA	7,4	0,96	0	probably_damaging	0,96	deleterious	0,04	neutral	4,29	neutral	-2,79	neutral	-2,23	medium_impact	2,52	neutral	0,74	neutral	0,53	deleterious	3,57	23,1	0,21	0,45	disease	0,8	neutral	0,48	disease	0,51	disease	0,6	2	deleterious	0,99	neutral	0,04	deleterious	5	deleterious	0,61	low_impact	-2,01	medium_impact	-0,57	medium_impact	1,37	0,3	0,8	15,69	12,56	P	0,6	P	0,76	polymorphism	1	0,03	rs386829133	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11570	11570	A	T	MI.18025	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	811	271	M	L	Ata/Tta	-2,96	0	0	benign	0,16	neutral	0,61	neutral	4,86	neutral	1,31	deleterious	-2,82	low_impact	1,53	neutral	0,7	neutral	0,56	deleterious	3,32	22,9	0,2	0,45	disease	0,62	disease	0,65	disease	0,51	neutral	0,24	5	neutral	0,28	deleterious	0,73	neutral	-6	deleterious	0,6	medium_impact	-0,04	medium_impact	0,31	medium_impact	0,39	0,17	0,8	47,71	9,47	N	0,26	N	0,98	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11570	11570	A	C	MI.18026	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	811	271	M	L	Ata/Cta	-2,96	0	0	benign	0,16	neutral	0,61	neutral	4,86	neutral	1,31	deleterious	-2,82	low_impact	1,53	neutral	0,7	neutral	0,56	deleterious	3,25	22,8	0,2	0,45	disease	0,62	disease	0,65	disease	0,51	neutral	0,24	5	neutral	0,28	deleterious	0,73	neutral	-6	deleterious	0,6	medium_impact	-0,04	medium_impact	0,31	medium_impact	0,39	0,17	0,8	47,71	9,47	N	0,27	N	0,98	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11570	11570	A	G	MI.18027	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	811	271	M	V	Ata/Gta	-2,96	0	0	benign	0,22	neutral	0,14	neutral	4,76	neutral	1,18	deleterious	-3,75	medium_impact	2,25	neutral	0,77	neutral	0,55	deleterious	2,73	21	0,19	0,45	disease	0,68	disease	0,72	disease	0,53	neutral	0,29	4	neutral	0,84	neutral	0,46	neutral	-3	deleterious	0,66	medium_impact	-0,2	medium_impact	-0,24	medium_impact	1,1	0,12	0,8	47,71	9,47	N	0,28	N	0,96	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11571	11571	T	A	MI.18028	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	812	271	M	K	aTa/aAa	6,93	1	0	possibly_damaging	0,86	deleterious	0,01	neutral	4,58	neutral	-2,55	deleterious	-5,63	high_impact	4,01	neutral	0,68	neutral	0,39	deleterious	3,86	23,5	0,04	0,35	disease	0,52	disease	0,87	disease	0,74	disease	0,74	5	deleterious	0,99	neutral	0,08	deleterious	5	deleterious	0,79	low_impact	-1,46	medium_impact	-0,92	high_impact	2,84	0,16	0,8	47,71	9,47	P	0,63	P	1	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11571	11571	T	C	MI.18029	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	812	271	M	T	aTa/aCa	6,93	1	0	possibly_damaging	0,71	deleterious	0,01	neutral	4,61	neutral	-0,8	deleterious	-5,63	medium_impact	3,46	neutral	0,68	neutral	0,46	deleterious	2,91	21,9	0,08	0,35	disease	0,53	disease	0,78	disease	0,67	disease	0,67	3	deleterious	0,99	neutral	0,15	deleterious	4	deleterious	0,76	low_impact	-1,08	medium_impact	-0,92	high_impact	2,3	0,08	0,8	47,71	9,47	P	0,62	P	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8536	8536	A	T	MI.1803	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	171	57	K	N	aaA/aaT	6,84	1	0	probably_damaging	0,96	neutral	0,43	neutral	0,68	deleterious	-5,5	deleterious	-4,65	high_impact	3,52	neutral	0,74	damaging	0,07	deleterious	3,87	23,5	0,52641227	0,85	disease	0,73	disease	0,51	disease	0,75	disease	0,65	3	neutral	0,96	neutral	0,24	deleterious	2	deleterious	0,81	low_impact	-2,07	medium_impact	0,22	medium_impact	1,92	0,69	0,85	20,59	8,73	P	0,63	P	0,7	disease_causing	0,97	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11572	11572	A	C	MI.18030	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	813	271	M	I	atA/atC	7,4	1	0	benign	0,04	neutral	0,39	neutral	4,82	neutral	0,8	deleterious	-3,75	low_impact	1,85	neutral	0,7	neutral	0,49	deleterious	3,43	23	0,21	0,45	disease	0,75	disease	0,73	disease	0,51	neutral	0,27	5	neutral	0,58	deleterious	0,68	neutral	-6	deleterious	0,73	medium_impact	0,58	medium_impact	0,09	medium_impact	0,7	0,16	0,8	47,71	9,47	P	0,57	P	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11572	11572	A	T	MI.18031	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	813	271	M	I	atA/atT	7,4	1	0	benign	0,04	neutral	0,39	neutral	4,82	neutral	0,8	deleterious	-3,75	low_impact	1,85	neutral	0,7	neutral	0,49	deleterious	3,48	23,1	0,21	0,45	disease	0,75	disease	0,73	disease	0,51	neutral	0,27	5	neutral	0,58	deleterious	0,68	neutral	-6	deleterious	0,73	medium_impact	0,58	medium_impact	0,09	medium_impact	0,7	0,16	0,8	47,71	9,47	P	0,58	P	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11573	11573	A	G	MI.18032	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	814	272	T	A	Aca/Gca	0,72	0,99	0	probably_damaging	1	neutral	0,37	neutral	4,75	neutral	1,92	deleterious	-4,62	low_impact	0,92	neutral	0,7	neutral	0,38	deleterious	3,45	23	0,27	0,45	disease	0,55	disease	0,54	neutral	0,44	neutral	0,35	3	deleterious	1	neutral	0,19	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	0,07	medium_impact	-0,22	0,28	0,8	46,19	9,02	N	0,42	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11573	11573	A	T	MI.18033	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	814	272	T	S	Aca/Tca	0,72	0,99	0	probably_damaging	1	neutral	0,3	neutral	4,64	neutral	-0,84	deleterious	-3,69	low_impact	1,9	neutral	0,78	neutral	0,32	deleterious	3,29	22,8	0,32	0,5	disease	0,71	disease	0,67	disease	0,52	neutral	0,48	0	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,75	low_impact	-3,54	medium_impact	0	medium_impact	0,75	0,58	0,8	46,19	9,02	N	0,44	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11573	11573	A	C	MI.18034	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	814	272	T	P	Aca/Cca	0,72	0,99	0	probably_damaging	1	deleterious	0,02	neutral	4,54	neutral	-2,96	deleterious	-5,59	medium_impact	3,46	neutral	0,65	damaging	0,14	deleterious	3,5	23,1	0,04	0,35	disease	0,8	disease	0,84	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-3,54	medium_impact	-0,75	high_impact	2,3	0,25	0,8	46,19	9,02	N	0,42	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11574	11574	C	A	MI.18035	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	815	272	T	K	aCa/aAa	6,93	1	0	probably_damaging	1	deleterious	0,03	neutral	4,57	neutral	-2,36	deleterious	-5,58	high_impact	4	neutral	0,71	damaging	0,12	deleterious	4,53	24,3	0,06	0,35	disease	0,81	disease	0,85	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-3,54	medium_impact	-0,64	high_impact	2,83	0,31	0,8	46,19	9,02	P	0,61	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11574	11574	C	T	MI.18036	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	815	272	T	M	aCa/aTa	6,93	1	0	probably_damaging	1	neutral	0,05	neutral	4,57	neutral	-1,41	deleterious	-5,58	medium_impact	2,65	neutral	0,71	damaging	0,14	deleterious	4	23,6	0,08	0,35	neutral	0,45	disease	0,76	disease	0,56	disease	0,54	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,5	0,51	0,8	46,19	9,02	P	0,55	P	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11576	11576	A	T	MI.18037	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	817	273	S	C	Agc/Tgc	-10,56	0	0	probably_damaging	0,99	deleterious	0,03	neutral	4,09	deleterious	-6,19	deleterious	-4,34	medium_impact	3,28	neutral	0,67	neutral	0,35	deleterious	3,51	23,1	0,06	0,35	disease	0,81	disease	0,8	disease	0,52	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,78	low_impact	-2,59	medium_impact	-0,64	high_impact	2,12	0,28	0,8	46,41	9,21	N	0,33	N	0,58	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11576	11576	A	G	MI.18038	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	817	273	S	G	Agc/Ggc	-10,56	0	0	benign	0,12	neutral	0,38	neutral	4,31	neutral	-1,44	neutral	-1,97	low_impact	1,53	neutral	0,62	neutral	0,62	neutral	1,45	13,05	0,13	0,4	disease	0,69	neutral	0,18	neutral	0,34	neutral	0,37	3	neutral	0,56	deleterious	0,63	neutral	-6	deleterious	0,71	medium_impact	0,1	medium_impact	0,08	medium_impact	0,39	0,46	0,8	46,41	9,21	N	0,43	N	0,29	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11576	11576	A	C	MI.18039	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	817	273	S	R	Agc/Cgc	-10,56	0	0	probably_damaging	0,98	deleterious	0	neutral	4,1	deleterious	-4,8	deleterious	-4,16	high_impact	4,32	neutral	0,68	neutral	0,33	deleterious	3,86	23,5	0,04	0,35	disease	0,61	disease	0,87	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,31	low_impact	-1,48	high_impact	3,15	0,41	0,8	46,41	9,21	N	0,42	N	0,94	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8536	8536	A	C	MI.1804	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	171	57	K	N	aaA/aaC	6,84	1	0	probably_damaging	0,96	neutral	0,43	neutral	0,68	deleterious	-5,5	deleterious	-4,65	high_impact	3,52	neutral	0,74	damaging	0,07	deleterious	3,8	23,4	0,52641227	0,85	disease	0,73	disease	0,51	disease	0,75	disease	0,65	3	neutral	0,96	neutral	0,24	deleterious	2	deleterious	0,81	low_impact	-2,07	medium_impact	0,22	medium_impact	1,92	0,69	0,85	20,59	8,73	P	0,63	P	0,7	disease_causing	0,97	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11577	11577	G	C	MI.18040	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	818	273	S	T	aGc/aCc	3,71	1	0	probably_damaging	0,92	neutral	0,06	neutral	4,23	neutral	-2,11	deleterious	-2,64	medium_impact	3,08	neutral	0,73	neutral	0,42	deleterious	3,35	22,9	0,23	0,45	disease	0,58	disease	0,59	disease	0,51	disease	0,51	0	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,74	low_impact	-1,71	medium_impact	-0,47	medium_impact	1,92	0,48	0,8	46,41	9,21	P	0,62	P	0,72	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11577	11577	G	A	MI.18041	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	818	273	S	N	aGc/aAc	3,71	1	0	probably_damaging	0,94	neutral	0,06	neutral	4,16	neutral	-2,97	neutral	-2,28	medium_impact	2,33	neutral	0,67	neutral	0,56	deleterious	3,63	23,2	0,37	0,5	disease	0,81	disease	0,66	neutral	0,44	neutral	0,35	3	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,79	low_impact	-1,84	medium_impact	-0,47	medium_impact	1,18	0,39	0,8	46,41	9,21	P	0,6	P	0,57	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11577	11577	G	T	MI.18042	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	818	273	S	I	aGc/aTc	3,71	1	0	probably_damaging	0,98	deleterious	0	neutral	4,09	deleterious	-5,66	deleterious	-5,28	high_impact	4,32	neutral	0,71	neutral	0,43	deleterious	4,12	23,8	0,06	0,35	disease	0,51	disease	0,88	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,31	low_impact	-1,48	high_impact	3,15	0,29	0,8	46,41	9,21	P	0,56	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11579	11579	T	G	MI.18043	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	820	274	S	A	Tcc/Gcc	-1,12	0	0	possibly_damaging	0,72	neutral	0,09	neutral	4,62	neutral	0,43	neutral	-2,15	low_impact	1,92	neutral	0,79	neutral	0,6	deleterious	3,67	23,3	0,25	0,45	disease	0,52	neutral	0,45	neutral	0,35	neutral	0,35	3	neutral	0,93	neutral	0,19	neutral	-3	deleterious	0,71	low_impact	-1,1	medium_impact	-0,36	medium_impact	0,77	0,38	0,8	13,51	9,43	N	0,37	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11579	11579	T	C	MI.18044	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	820	274	S	P	Tcc/Ccc	-1,12	0	0	probably_damaging	0,98	deleterious	0,02	neutral	4,56	neutral	-2,64	deleterious	-4,13	medium_impact	2,89	neutral	0,64	neutral	0,38	deleterious	3,99	23,6	0,05	0,35	disease	0,87	disease	0,85	disease	0,59	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,87	low_impact	-2,31	medium_impact	-0,75	medium_impact	1,73	0,27	0,8	13,51	9,43	N	0,31	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11579	11579	T	A	MI.18045	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	820	274	S	T	Tcc/Acc	-1,12	0	0	possibly_damaging	0,85	neutral	0,06	neutral	4,65	neutral	1,06	neutral	-2,26	medium_impact	2,04	neutral	0,74	neutral	0,59	deleterious	2,77	21,2	0,28	0,45	neutral	0,37	neutral	0,46	neutral	0,33	neutral	0,42	2	neutral	0,97	neutral	0,11	NA	0	deleterious	0,69	low_impact	-1,43	medium_impact	-0,47	medium_impact	0,89	0,43	0,8	13,51	9,43	N	0,48	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11580	11580	C	T	MI.18046	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	821	274	S	F	tCc/tTc	1,41	0,01	0	probably_damaging	0,92	neutral	0,39	neutral	4,67	neutral	0,96	deleterious	-4,69	low_impact	1,08	neutral	0,67	neutral	0,51	deleterious	4,28	24	0,1	0,4	disease	0,62	disease	0,71	neutral	0,4	neutral	0,28	4	neutral	0,92	neutral	0,24	neutral	-2	deleterious	0,77	low_impact	-1,71	medium_impact	0,09	medium_impact	-0,06	0,19	0,8	13,51	9,43	N	0,3	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11580	11580	C	A	MI.18047	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	821	274	S	Y	tCc/tAc	1,41	0,01	0	probably_damaging	0,97	neutral	0,1	neutral	4,57	neutral	-1,26	deleterious	-4,77	medium_impact	2,35	neutral	0,76	neutral	0,41	deleterious	4,11	23,8	0,07	0,35	disease	0,79	disease	0,78	neutral	0,44	disease	0,61	2	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,81	low_impact	-2,14	medium_impact	-0,33	medium_impact	1,2	0,22	0,8	13,51	9,43	N	0,38	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11580	11580	C	G	MI.18048	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	821	274	S	C	tCc/tGc	1,41	0,01	0	probably_damaging	0,98	deleterious	0,03	neutral	4,56	neutral	-2,15	deleterious	-3,56	medium_impact	2,69	neutral	0,72	neutral	0,39	deleterious	3,58	23,2	0,08	0,35	disease	0,87	disease	0,75	neutral	0,37	disease	0,59	2	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,78	low_impact	-2,31	medium_impact	-0,64	medium_impact	1,54	0,26	0,8	13,51	9,43	N	0,37	N	0,58	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11582	11582	A	C	MI.18049	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	823	275	I	L	Atc/Ctc	-20	0	0	benign	0,33	neutral	0,17	neutral	4,59	neutral	-0,04	neutral	-1,84	medium_impact	2,04	neutral	0,76	neutral	0,64	deleterious	3,82	23,4	0,23	0,45	neutral	0,49	disease	0,57	neutral	0,45	neutral	0,2	6	neutral	0,8	neutral	0,42	neutral	-3	deleterious	0,65	medium_impact	-0,43	medium_impact	-0,18	medium_impact	0,89	0,44	0,8	17,65	17,37	N	0,39	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8537	8537	A	C	MI.1805	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	172	58	I	L	Atc/Ctc	5,91	1	0,01	possibly_damaging	0,6	neutral	0,48	neutral	1,29	deleterious	-3,11	neutral	-1,78	medium_impact	3,44	neutral	1	neutral	0,35	deleterious	3,28	22,8	0,41111942	0,85	neutral	0,36	neutral	0,29	disease	0,68	neutral	0,22	6	neutral	0,59	neutral	0,44	NA	0	neutral	0,39	medium_impact	-0,92	medium_impact	0,27	medium_impact	1,85	0,8	0,85	NA	NA	P	0,67	P	0,61	polymorphism	0,98	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11582	11582	A	T	MI.18050	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	823	275	I	F	Atc/Ttc	-20	0	0	probably_damaging	0,9	neutral	0,05	neutral	4,49	neutral	-1,68	deleterious	-3,7	medium_impact	3,04	neutral	0,7	neutral	0,39	deleterious	3,9	23,5	0,16	0,45	neutral	0,35	disease	0,73	disease	0,67	disease	0,66	3	deleterious	0,98	neutral	0,08	deleterious	1	deleterious	0,72	low_impact	-1,61	medium_impact	-0,52	medium_impact	1,88	0,39	0,8	17,65	17,37	N	0,4	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11582	11582	A	G	MI.18051	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	823	275	I	V	Atc/Gtc	-20	0	0	benign	0,33	neutral	0,17	neutral	4,62	neutral	0,2	neutral	-0,88	low_impact	1,82	neutral	0,79	neutral	0,59	deleterious	3,01	22,3	0,42	0,55	neutral	0,45	neutral	0,34	disease	0,57	neutral	0,43	1	neutral	0,8	neutral	0,42	neutral	-6	deleterious	0,63	medium_impact	-0,43	medium_impact	-0,18	medium_impact	0,68	0,36	0,8	17,65	17,37	N	0,36	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11583	11583	T	A	MI.18052	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	824	275	I	N	aTc/aAc	4,63	1	0	possibly_damaging	0,83	neutral	0,15	neutral	4,47	deleterious	-3,13	deleterious	-6,43	medium_impact	2,73	neutral	0,68	neutral	0,4	deleterious	4,43	24,2	0,1	0,4	disease	0,92	disease	0,81	disease	0,66	disease	0,69	4	neutral	0,92	neutral	0,16	NA	0	deleterious	0,82	low_impact	-1,37	medium_impact	-0,22	medium_impact	1,58	0,2	0,8	17,65	17,37	P	0,55	P	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11583	11583	T	C	MI.18053	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	824	275	I	T	aTc/aCc	4,63	1	0	benign	0,02	neutral	0,12	neutral	4,51	neutral	-1,66	deleterious	-4,49	low_impact	1,46	neutral	0,75	neutral	0,68	deleterious	2,31	18,2	0,11	0,4	disease	0,81	disease	0,57	neutral	0,48	neutral	0,37	3	neutral	0,88	deleterious	0,55	neutral	-6	deleterious	0,77	medium_impact	0,87	medium_impact	-0,28	medium_impact	0,32	0,23	0,8	17,65	17,37	P	0,51	P	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11583	11583	T	G	MI.18054	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	824	275	I	S	aTc/aGc	4,63	1	0	possibly_damaging	0,56	neutral	0,12	neutral	4,51	neutral	-1,82	deleterious	-5,49	medium_impact	2,6	neutral	0,69	neutral	0,43	deleterious	4,32	24	0,04	0,35	disease	0,68	disease	0,82	disease	0,62	disease	0,66	3	neutral	0,88	neutral	0,28	NA	0	deleterious	0,8	medium_impact	-0,82	medium_impact	-0,28	medium_impact	1,45	0,16	0,8	17,65	17,37	P	0,58	P	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11584	11584	C	G	MI.18055	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	825	275	I	M	atC/atG	4,63	1	0	probably_damaging	0,93	neutral	0,16	neutral	4,51	neutral	-0,93	deleterious	-2,73	medium_impact	2,02	neutral	0,77	neutral	0,55	deleterious	3,33	22,9	0,26	0,45	neutral	0,44	disease	0,6	disease	0,56	neutral	0,38	2	neutral	0,96	neutral	0,12	deleterious	1	deleterious	0,71	low_impact	-1,77	medium_impact	-0,2	medium_impact	0,87	0,44	0,8	17,65	17,37	P	0,57	P	0,75	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11584	11584	C	A	MI.18056	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	825	275	I	M	atC/atA	4,63	1	0	probably_damaging	0,93	neutral	0,16	neutral	4,51	neutral	-0,93	deleterious	-2,73	medium_impact	2,02	neutral	0,77	neutral	0,55	deleterious	3,7	23,3	0,26	0,45	neutral	0,44	disease	0,6	disease	0,56	neutral	0,38	2	neutral	0,96	neutral	0,12	deleterious	1	deleterious	0,71	low_impact	-1,77	medium_impact	-0,2	medium_impact	0,87	0,44	0,8	17,65	17,37	P	0,58	P	0,75	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11585	11585	T	A	MI.18057	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	826	276	C	S	Tgc/Agc	-2,73	0	0	benign	0,03	neutral	0,07	neutral	4,63	neutral	0,36	deleterious	-9,37	high_impact	3,56	damaging	0,53	neutral	0,74	neutral	1,57	13,66	0,08	0,35	disease	0,66	disease	0,87	disease	0,68	disease	0,71	4	neutral	0,93	deleterious	0,52	neutral	-2	neutral	0,31	medium_impact	0,7	medium_impact	-0,43	high_impact	2,4	0,22	0,8	46,41	9,11	N	0,46	N	0,24	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11585	11585	T	G	MI.18058	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	826	276	C	G	Tgc/Ggc	-2,73	0	0	possibly_damaging	0,48	deleterious	0	neutral	4,83	neutral	1,44	deleterious	-11,25	medium_impact	3,44	damaging	0,55	neutral	0,64	neutral	1,37	12,61	0,07	0,35	disease	0,78	disease	0,89	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	4	neutral	0,33	medium_impact	-0,69	low_impact	-1,48	high_impact	2,28	0,23	0,8	46,41	9,11	N	0,4	N	0,75	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11585	11585	T	C	MI.18059	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	826	276	C	R	Tgc/Cgc	-2,73	0	0	possibly_damaging	0,75	deleterious	0	neutral	4,53	neutral	-1,62	deleterious	-11,25	high_impact	4,54	damaging	0,57	neutral	0,48	neutral	1,64	14,1	0,05	0,35	disease	0,78	disease	0,93	disease	0,8	disease	0,73	5	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,51	low_impact	-1,17	low_impact	-1,48	high_impact	3,37	0,09	0,8	46,41	9,11	P	0,58	P	0,87	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8537	8537	A	G	MI.1806	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	172	58	I	V	Atc/Gtc	5,91	1	0,01	possibly_damaging	0,6	neutral	0,56	neutral	1,35	neutral	-2,67	neutral	-0,83	medium_impact	3,44	neutral	1	neutral	0,64	deleterious	2,56	19,88	0,72936886	0,85	neutral	0,25	neutral	0,15	disease	0,58	neutral	0,2	6	neutral	0,55	deleterious	0,48	NA	0	neutral	0,34	medium_impact	-0,92	medium_impact	0,35	medium_impact	1,85	0,61	0,85	NA	NA	P	0,63	P	0,15	polymorphism	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11586	11586	G	C	MI.18060	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	827	276	C	S	tGc/tCc	5,78	1	0	benign	0,03	neutral	0,07	neutral	4,63	neutral	0,36	deleterious	-9,37	high_impact	3,56	damaging	0,53	neutral	0,74	neutral	1,27	12,12	0,08	0,35	disease	0,66	disease	0,87	disease	0,68	disease	0,71	4	neutral	0,93	deleterious	0,52	neutral	-2	neutral	0,31	medium_impact	0,7	medium_impact	-0,43	high_impact	2,4	0,22	0,8	46,41	9,11	P	0,6	P	0,24	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11586	11586	G	A	MI.18061	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	827	276	C	Y	tGc/tAc	5,78	1	0	possibly_damaging	0,85	deleterious	0	neutral	4,53	neutral	-1,08	deleterious	-10,3	high_impact	4,54	damaging	0,59	neutral	0,45	deleterious	1,96	15,99	0,06	0,35	disease	0,57	disease	0,92	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,08	deleterious	5	deleterious	0,54	low_impact	-1,43	low_impact	-1,48	high_impact	3,37	0,27	0,8	46,41	9,11	P	0,66	P	0,92	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11586	11586	G	T	MI.18062	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	827	276	C	F	tGc/tTc	5,78	1	0	possibly_damaging	0,85	deleterious	0	neutral	4,53	neutral	-0,79	deleterious	-10,3	high_impact	4,54	damaging	0,56	neutral	0,51	deleterious	2,18	17,37	0,05	0,35	disease	0,68	disease	0,93	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,08	deleterious	5	deleterious	0,51	low_impact	-1,43	low_impact	-1,48	high_impact	3,37	0,16	0,8	46,41	9,11	P	0,65	P	0,94	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11587	11587	C	G	MI.18063	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	828	276	C	W	tgC/tgG	7,4	1	0	probably_damaging	0,92	deleterious	0	neutral	4,52	deleterious	-3,08	deleterious	-10,3	high_impact	4,54	damaging	0,59	neutral	0,49	deleterious	3,93	23,5	0,04	0,35	disease	0,69	disease	0,93	disease	0,79	disease	0,8	6	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,72	low_impact	-1,71	low_impact	-1,48	high_impact	3,37	0,21	0,8	46,41	9,11	P	0,63	P	0,94	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11587	11587	C	A	MI.18064	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	828	276	C	W	tgC/tgA	7,4	1	0	probably_damaging	0,92	deleterious	0	neutral	4,52	deleterious	-3,08	deleterious	-10,3	high_impact	4,54	damaging	0,59	neutral	0,49	deleterious	4,26	23,9	0,04	0,35	disease	0,69	disease	0,93	disease	0,79	disease	0,8	6	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,72	low_impact	-1,71	low_impact	-1,48	high_impact	3,37	0,21	0,8	46,41	9,11	P	0,64	P	0,94	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11588	11588	C	A	MI.18065	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	829	277	L	M	Cta/Ata	-1,58	0	0	probably_damaging	1	neutral	0,18	neutral	4,12	deleterious	-3,3	neutral	-1,56	medium_impact	2,4	neutral	0,79	neutral	0,7	deleterious	2,66	20,6	0,19	0,45	disease	0,69	neutral	0,36	neutral	0,44	disease	0,6	2	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	-0,17	medium_impact	1,25	0,54	0,8	42,05	7,89	N	0,39	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11588	11588	C	G	MI.18066	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	829	277	L	V	Cta/Gta	-1,58	0	0	probably_damaging	1	neutral	0,08	neutral	4,11	neutral	-2	deleterious	-2,65	medium_impact	2,82	neutral	0,68	damaging	0,16	deleterious	3,45	23	0,19	0,45	neutral	0,37	disease	0,61	disease	0,61	disease	0,54	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	-0,39	medium_impact	1,66	0,51	0,8	42,05	7,89	N	0,32	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11589	11589	T	A	MI.18067	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	830	277	L	Q	cTa/cAa	-4,81	0	0	probably_damaging	1	deleterious	0	neutral	4,02	deleterious	-5,82	deleterious	-5,34	high_impact	4,37	neutral	0,65	damaging	0,14	deleterious	4,1	23,7	0,03	0,35	disease	0,91	disease	0,8	disease	0,68	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,2	0,31	0,8	42,05	7,89	N	0,35	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11589	11589	T	G	MI.18068	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	830	277	L	R	cTa/cGa	-4,81	0	0	probably_damaging	1	deleterious	0	neutral	4,03	deleterious	-5,49	deleterious	-5,4	high_impact	4,37	damaging	0,59	damaging	0,13	deleterious	4,23	23,9	0,02	0,35	disease	0,9	disease	0,88	disease	0,78	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,2	0,2	0,8	42,05	7,89	N	0,43	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11589	11589	T	C	MI.18069	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	830	277	L	P	cTa/cCa	-4,81	0	0	probably_damaging	1	deleterious	0	neutral	4,02	deleterious	-5,9	deleterious	-6,33	high_impact	4,37	damaging	0,52	damaging	0,14	deleterious	3,93	23,5	0,03	0,35	disease	0,93	disease	0,85	disease	0,77	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,2	0,34	0,8	42,05	7,89	N	0,42	N	0,98	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8537	8537	A	T	MI.1807	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	172	58	I	F	Atc/Ttc	5,91	1	0,01	possibly_damaging	0,9	neutral	0,45	neutral	1,22	deleterious	-5,38	deleterious	-3,53	medium_impact	3,44	neutral	1	neutral	0,37	deleterious	3,59	23,2	0,3177178	0,85	disease	0,68	neutral	0,35	disease	0,72	neutral	0,32	4	neutral	0,9	neutral	0,28	NA	0	deleterious	0,69	low_impact	-1,66	medium_impact	0,24	medium_impact	1,85	0,7	0,85	NA	NA	P	0,71	P	0,57	disease_causing	0,66	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11591	11591	C	T	MI.18070	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	832	278	R	W	Cga/Tga	-3,19	0	0	probably_damaging	1	deleterious	0,04	neutral	4,54	deleterious	-3,64	deleterious	-7,5	high_impact	3,81	neutral	0,62	damaging	0,19	deleterious	5,21	25,5	0,05	0,35	disease	0,88	disease	0,88	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-3,54	medium_impact	-0,57	high_impact	2,64	0,76	0,85	47,06	9,55	N	0,34	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11591	11591	C	G	MI.18071	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	832	278	R	G	Cga/Gga	-3,19	0	0	probably_damaging	1	neutral	0,08	neutral	4,6	neutral	-0,5	deleterious	-6,56	medium_impact	3	neutral	0,62	neutral	0,36	deleterious	4,27	24	0,05	0,35	disease	0,61	disease	0,81	disease	0,73	disease	0,62	2	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,39	medium_impact	1,84	0,28	0,8	47,06	9,55	N	0,31	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11592	11592	G	C	MI.18072	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	833	278	R	P	cGa/cCa	7,17	1	0	probably_damaging	1	deleterious	0,03	neutral	4,55	neutral	-2,93	deleterious	-6,56	high_impact	4,35	damaging	0,59	damaging	0,25	deleterious	4,28	24	0,03	0,35	disease	0,83	disease	0,89	disease	0,81	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,87	low_impact	-3,54	medium_impact	-0,64	high_impact	3,18	0,17	0,8	47,06	9,55	P	0,66	P	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11592	11592	G	A	MI.18073	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	833	278	R	Q	cGa/cAa	7,17	1	0	probably_damaging	1	neutral	0,08	neutral	4,61	neutral	-1,94	deleterious	-3,73	medium_impact	2,6	neutral	0,68	neutral	0,31	deleterious	4,61	24,4	0,17	0,45	disease	0,79	disease	0,77	neutral	0,48	neutral	0,29	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	-0,39	medium_impact	1,45	0,65	0,8	47,06	9,55	P	0,63	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11592	11592	G	T	MI.18074	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	833	278	R	L	cGa/cTa	7,17	1	0	probably_damaging	1	neutral	0,14	neutral	4,58	neutral	-0,69	deleterious	-6,56	medium_impact	2,86	neutral	0,66	neutral	0,31	deleterious	4,38	24,1	0,06	0,35	neutral	0,37	disease	0,9	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,24	medium_impact	1,7	0,13	0,8	47,06	9,55	P	0,57	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11594	11594	C	A	MI.18075	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	835	279	Q	K	Caa/Aaa	-12,63	0	0	benign	0,08	deleterious	0	neutral	4,11	deleterious	-3,51	deleterious	-3,8	medium_impact	3,46	damaging	0,57	neutral	0,31	deleterious	3,96	23,6	0,09	0,35	disease	0,77	disease	0,86	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,46	deleterious	1	deleterious	0,84	medium_impact	0,28	low_impact	-1,48	high_impact	2,3	0,24	0,8	47,06	9,25	N	0,32	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11594	11594	C	G	MI.18076	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	835	279	Q	E	Caa/Gaa	-12,63	0	0	possibly_damaging	0,64	neutral	0,05	neutral	4,15	deleterious	-3,45	deleterious	-2,85	high_impact	3,63	neutral	0,66	neutral	0,38	deleterious	3,1	22,5	0,15	0,4	disease	0,8	disease	0,78	disease	0,74	disease	0,71	4	neutral	0,95	neutral	0,21	deleterious	1	deleterious	0,83	medium_impact	-0,95	medium_impact	-0,52	high_impact	2,47	0,24	0,8	47,06	9,25	N	0,37	N	0,93	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11595	11595	A	G	MI.18077	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	836	279	Q	R	cAa/cGa	4,4	1	0	possibly_damaging	0,74	deleterious	0	neutral	4,07	deleterious	-4,29	deleterious	-3,8	high_impact	4,61	damaging	0,55	neutral	0,32	deleterious	3,25	22,8	0,11	0,4	disease	0,77	disease	0,86	disease	0,81	disease	0,73	5	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,85	low_impact	-1,14	low_impact	-1,48	high_impact	3,44	0,19	0,8	47,06	9,25	P	0,67	P	0,88	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11595	11595	A	C	MI.18078	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	836	279	Q	P	cAa/cCa	4,4	1	0	probably_damaging	0,96	deleterious	0	neutral	4,03	deleterious	-6,27	deleterious	-5,7	high_impact	4,61	neutral	0,63	neutral	0,42	deleterious	3,16	22,6	0,03	0,35	disease	0,71	disease	0,88	disease	0,83	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,87	low_impact	-2,01	low_impact	-1,48	high_impact	3,44	0,11	0,8	47,06	9,25	P	0,63	P	0,97	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11595	11595	A	T	MI.18079	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	836	279	Q	L	cAa/cTa	4,4	1	0	possibly_damaging	0,88	deleterious	0,01	neutral	4,08	deleterious	-5,68	deleterious	-6,66	medium_impact	3,08	damaging	0,6	neutral	0,4	deleterious	3,6	23,2	0,03	0,35	neutral	0,5	disease	0,89	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	4	deleterious	0,8	low_impact	-1,53	medium_impact	-0,92	medium_impact	1,92	0,12	0,8	47,06	9,25	P	0,51	P	0,97	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8538	8538	T	G	MI.1808	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	173	58	I	S	aTc/aGc	1,75	0,93	0	possibly_damaging	0,9	neutral	0,39	neutral	1,24	deleterious	-5,9	deleterious	-5,04	medium_impact	3,1	neutral	1	neutral	0,35	deleterious	4,26	23,9	0,30623305	0,85	disease	0,69	disease	0,54	disease	0,7	disease	0,65	3	neutral	0,9	neutral	0,25	NA	0	deleterious	0,73	low_impact	-1,66	medium_impact	0,18	medium_impact	1,56	0,44	0,85	NA	NA	P	0,55	P	0,47	polymorphism	0,97	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11596	11596	A	C	MI.18080	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	837	279	Q	H	caA/caC	6,7	1	0	probably_damaging	0,98	deleterious	0	neutral	4,04	deleterious	-5,85	deleterious	-4,75	high_impact	3,91	damaging	0,59	neutral	0,32	deleterious	3,44	23	0,07	0,35	disease	0,82	disease	0,8	disease	0,82	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,31	low_impact	-1,48	high_impact	2,74	0,4	0,8	47,06	9,25	P	0,63	P	0,97	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11596	11596	A	T	MI.18081	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	837	279	Q	H	caA/caT	6,7	1	0	probably_damaging	0,98	deleterious	0	neutral	4,04	deleterious	-5,85	deleterious	-4,75	high_impact	3,91	damaging	0,59	neutral	0,32	deleterious	3,59	23,2	0,07	0,35	disease	0,82	disease	0,8	disease	0,82	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,31	low_impact	-1,48	high_impact	2,74	0,4	0,8	47,06	9,25	P	0,63	P	0,97	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11597	11597	A	G	MI.18082	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	838	280	T	A	Aca/Gca	4,63	1	0	benign	0,12	neutral	0,05	neutral	4,46	neutral	-1,82	deleterious	-3,99	medium_impact	2,23	neutral	0,7	neutral	0,69	deleterious	3,36	22,9	0,24	0,45	disease	0,63	neutral	0,5	neutral	0,5	neutral	0,31	4	neutral	0,94	neutral	0,47	neutral	-3	deleterious	0,75	medium_impact	0,1	medium_impact	-0,52	medium_impact	1,08	0,28	0,8	13,94	14,75	P	0,58	P	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11597	11597	A	C	MI.18083	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	838	280	T	P	Aca/Cca	4,63	1	0	probably_damaging	0,96	deleterious	0,02	neutral	4,4	deleterious	-3,37	deleterious	-5,25	low_impact	1,75	neutral	0,64	neutral	0,52	deleterious	3,52	23,1	0,03	0,35	disease	0,82	disease	0,78	disease	0,61	disease	0,51	0	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,84	low_impact	-2,01	medium_impact	-0,75	medium_impact	0,61	0,19	0,8	13,94	14,75	N	0,48	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11597	11597	A	T	MI.18084	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	838	280	T	S	Aca/Tca	4,63	1	0	possibly_damaging	0,74	neutral	0,32	neutral	4,54	neutral	-1,05	deleterious	-3,39	low_impact	1,81	neutral	0,73	neutral	0,57	deleterious	3,24	22,8	0,43	0,55	disease	0,62	disease	0,62	neutral	0,33	neutral	0,24	5	neutral	0,79	neutral	0,29	neutral	-3	deleterious	0,77	low_impact	-1,14	medium_impact	0,02	medium_impact	0,67	0,57	0,8	13,94	14,75	P	0,58	P	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11598	11598	C	T	MI.18085	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	839	280	T	M	aCa/aTa	4,63	1	0	probably_damaging	0,98	neutral	0,06	neutral	4,42	deleterious	-4,23	deleterious	-5,2	medium_impact	2,66	neutral	0,71	neutral	0,56	deleterious	4,05	23,7	0,1	0,4	disease	0,88	disease	0,75	disease	0,52	disease	0,6	2	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,79	low_impact	-2,31	medium_impact	-0,47	medium_impact	1,51	0,38	0,8	13,94	14,75	P	0,57	P	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11598	11598	C	A	MI.18086	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	839	280	T	K	aCa/aAa	4,63	1	0	benign	0,12	deleterious	0,01	neutral	4,44	neutral	-0,61	deleterious	-5,25	medium_impact	2,47	neutral	0,69	neutral	0,4	deleterious	4,56	24,4	0,08	0,35	disease	0,57	disease	0,83	disease	0,62	disease	0,66	3	deleterious	0,99	neutral	0,45	deleterious	1	deleterious	0,81	medium_impact	0,1	medium_impact	-0,92	medium_impact	1,32	0,33	0,8	13,94	14,75	N	0,48	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11600	11600	G	A	MI.18087	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	841	281	D	N	Gac/Aac	-2,96	0	0	probably_damaging	0,94	deleterious	0	neutral	4,27	neutral	-2,49	deleterious	-4,72	medium_impact	3,33	damaging	0,41	neutral	0,39	deleterious	4,23	23,9	0,25	0,45	disease	0,77	disease	0,76	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,81	low_impact	-1,84	low_impact	-1,48	high_impact	2,17	0,86	0,9	47,71	9,41	P	0,56	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11600	11600	G	T	MI.18088	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	841	281	D	Y	Gac/Tac	-2,96	0	0	probably_damaging	0,99	deleterious	0	neutral	4,16	deleterious	-6,78	deleterious	-8,51	high_impact	4,64	damaging	0,43	neutral	0,28	deleterious	3,92	23,5	0,02	0,35	disease	0,71	disease	0,89	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,59	low_impact	-1,48	high_impact	3,46	0,11	0,8	47,71	9,41	P	0,62	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11600	11600	G	C	MI.18089	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	841	281	D	H	Gac/Cac	-2,96	0	0	probably_damaging	0,99	deleterious	0	neutral	4,18	deleterious	-4,9	deleterious	-6,61	high_impact	3,96	damaging	0,41	neutral	0,28	deleterious	3,68	23,3	0,04	0,35	disease	0,81	disease	0,8	disease	0,77	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,59	low_impact	-1,48	high_impact	2,79	0,42	0,8	47,71	9,41	P	0,61	P	0,99	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8538	8538	T	A	MI.1809	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	173	58	I	N	aTc/aAc	1,75	0,93	0	probably_damaging	0,97	neutral	0,17	neutral	1,21	deleterious	-6,9	deleterious	-6,05	medium_impact	3,44	neutral	1	neutral	0,37	deleterious	4,65	24,5	0,29671997	0,85	disease	0,82	disease	0,62	disease	0,71	disease	0,65	3	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,79	low_impact	-2,19	medium_impact	-0,1	medium_impact	1,85	0,51	0,85	NA	NA	P	0,58	P	0,72	polymorphism	0,98	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11601	11601	A	C	MI.18090	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	842	281	D	A	gAc/gCc	6,01	1	0	probably_damaging	0,91	deleterious	0	neutral	4,22	deleterious	-4,51	deleterious	-7,56	high_impact	4,3	damaging	0,49	neutral	0,4	deleterious	3,65	23,2	0,04	0,35	neutral	0,39	disease	0,73	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,77	low_impact	-1,66	low_impact	-1,48	high_impact	3,13	0,18	0,8	47,71	9,41	P	0,58	P	0,93	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11601	11601	A	G	MI.18091	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	842	281	D	G	gAc/gGc	6,01	1	0	probably_damaging	0,95	deleterious	0	neutral	4,18	deleterious	-5,23	deleterious	-6,62	high_impact	4,64	damaging	0,41	neutral	0,38	deleterious	3,99	23,6	0,04	0,35	disease	0,68	disease	0,84	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,78	low_impact	-1,92	low_impact	-1,48	high_impact	3,46	0,25	0,8	47,71	9,41	P	0,78	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11601	11601	A	T	MI.18092	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	842	281	D	V	gAc/gTc	6,01	1	0	probably_damaging	0,98	deleterious	0	neutral	4,18	deleterious	-5,77	deleterious	-8,51	high_impact	4,64	damaging	0,39	neutral	0,33	deleterious	3,76	23,3	0,02	0,35	neutral	0,35	disease	0,86	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,31	low_impact	-1,48	high_impact	3,46	0,13	0,8	47,71	9,41	P	0,72	P	0,99	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11602	11602	C	A	MI.18093	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	843	281	D	E	gaC/gaA	8,55	1	0	benign	0,22	deleterious	0	neutral	4,25	deleterious	-3,48	deleterious	-3,78	high_impact	4,09	damaging	0,41	neutral	0,35	deleterious	4,29	24	0,11	0,4	disease	0,78	disease	0,73	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,83	medium_impact	-0,2	low_impact	-1,48	high_impact	2,92	0,44	0,8	47,71	9,41	P	0,74	P	0,95	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11602	11602	C	G	MI.18094	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	843	281	D	E	gaC/gaG	8,55	1	0	benign	0,22	deleterious	0	neutral	4,25	deleterious	-3,48	deleterious	-3,78	high_impact	4,09	damaging	0,41	neutral	0,35	deleterious	3,96	23,6	0,11	0,4	disease	0,78	disease	0,73	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,83	medium_impact	-0,2	low_impact	-1,48	high_impact	2,92	0,44	0,8	47,71	9,41	P	0,73	P	0,95	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11603	11603	C	A	MI.18095	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	844	282	L	M	Cta/Ata	-0,89	0	0	probably_damaging	1	neutral	0,25	neutral	4,45	neutral	-2,06	neutral	-1,83	low_impact	1,85	neutral	0,73	neutral	0,48	deleterious	3,93	23,5	0,31	0,45	disease	0,53	neutral	0,38	neutral	0,44	neutral	0,32	4	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,73	low_impact	-3,54	medium_impact	-0,07	medium_impact	0,7	0,66	0,8	44,88	8,38	N	0,4	N	0,9	polymorphism	1	0,02	rs28669780	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11603	11603	C	G	MI.18096	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	844	282	L	V	Cta/Gta	-0,89	0	0	probably_damaging	1	neutral	0,16	neutral	4,5	neutral	-1,23	deleterious	-2,81	medium_impact	2,52	neutral	0,65	damaging	0,13	deleterious	3,46	23	0,27	0,45	neutral	0,43	disease	0,5	disease	0,59	disease	0,56	1	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	-0,2	medium_impact	1,37	0,56	0,8	44,88	8,38	N	0,32	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11604	11604	T	A	MI.18097	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	845	282	L	Q	cTa/cAa	-0,66	0	0	probably_damaging	1	deleterious	0,02	neutral	4,34	deleterious	-5,19	deleterious	-5,63	high_impact	3,67	damaging	0,59	damaging	0,1	deleterious	4,18	23,8	0,04	0,35	disease	0,75	disease	0,74	disease	0,61	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,54	medium_impact	-0,75	high_impact	2,51	0,19	0,8	44,88	8,38	N	0,27	N	0,99	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11604	11604	T	C	MI.18098	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	845	282	L	P	cTa/cCa	-0,66	0	0	probably_damaging	1	deleterious	0	neutral	4,34	deleterious	-4,76	deleterious	-6,59	high_impact	4,36	damaging	0,54	damaging	0,1	deleterious	3,97	23,6	0,03	0,35	disease	0,92	disease	0,77	disease	0,73	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	3,19	0,3	0,8	44,88	8,38	N	0,37	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11604	11604	T	G	MI.18099	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	845	282	L	R	cTa/cGa	-0,66	0	0	probably_damaging	1	deleterious	0	neutral	4,35	deleterious	-5,02	deleterious	-5,64	high_impact	4,36	damaging	0,56	damaging	0,09	deleterious	4,23	23,9	0,03	0,35	disease	0,89	disease	0,79	disease	0,73	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,19	0,09	0,8	44,88	8,38	N	0,38	N	1	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8611	8611	C	G	MI.181	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	85	29	L	V	Cta/Gta	-6,12	0	0	probably_damaging	0,99	neutral	0,19	neutral	4,36	neutral	-0,63	neutral	-0,68	low_impact	0,9	neutral	0,89	neutral	0,88	neutral	1,75	14,67	0,46	0,65	neutral	0,3	neutral	0,26	neutral	0,39	neutral	0,44	1	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,7	low_impact	-2,65	medium_impact	-0,06	medium_impact	-0,33	0,7	0,9	17,26	17,02	N	0,48	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8538	8538	T	C	MI.1810	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	173	58	I	T	aTc/aCc	1,75	0,93	0	possibly_damaging	0,9	neutral	0,48	neutral	1,28	deleterious	-5,35	deleterious	-4,13	medium_impact	2	neutral	1	neutral	0,82	deleterious	2,28	18,03	0,46155204	0,85	neutral	0,5	neutral	0,39	neutral	0,43	neutral	0,12	8	neutral	0,89	neutral	0,29	NA	0	deleterious	0,67	low_impact	-1,66	medium_impact	0,27	medium_impact	0,62	0,58	0,85	NA	NA	N	0,52	P	0,18	polymorphism	0,99	0,14	rs878853010	Uncertain significance	not_provided	RCV000224039.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	11606	11606	A	G	MI.18100	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	847	283	K	E	Aaa/Gaa	0,72	0,99	0	probably_damaging	1	deleterious	0	neutral	3,18	deleterious	-6,61	deleterious	-3,78	high_impact	4,63	damaging	0,52	damaging	0,07	deleterious	4,08	23,7	0,03	0,35	disease	0,54	disease	0,85	disease	0,76	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,28	0,8	47,06	9,38	P	0,55	P	0,87	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11606	11606	A	C	MI.18101	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	847	283	K	Q	Aaa/Caa	0,72	0,99	0	probably_damaging	1	deleterious	0	neutral	3,2	deleterious	-5,9	deleterious	-3,78	high_impact	4,63	damaging	0,52	damaging	0,07	deleterious	3,53	23,1	0,09	0,35	disease	0,62	disease	0,8	disease	0,73	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,31	0,8	47,06	9,38	P	0,54	P	0,86	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11607	11607	A	C	MI.18102	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	848	283	K	T	aAa/aCa	8,55	1	0	probably_damaging	1	deleterious	0	neutral	3,17	deleterious	-7,12	deleterious	-5,67	high_impact	4,08	damaging	0,52	damaging	0,07	deleterious	3,65	23,2	0,04	0,35	neutral	0,39	disease	0,8	disease	0,73	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	2,91	0,11	0,8	47,06	9,38	P	0,54	P	0,77	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11607	11607	A	T	MI.18103	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	848	283	K	M	aAa/aTa	8,55	1	0	probably_damaging	1	deleterious	0	neutral	3,16	deleterious	-8,56	deleterious	-5,68	high_impact	4,63	damaging	0,55	damaging	0,06	deleterious	3,9	23,5	0,03	0,35	disease	0,84	disease	0,83	disease	0,72	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,12	0,8	47,06	9,38	P	0,57	P	0,42	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11608	11608	A	T	MI.18104	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	849	283	K	N	aaA/aaT	8,55	1	0	probably_damaging	1	deleterious	0	neutral	3,17	deleterious	-6,97	deleterious	-4,73	high_impact	4,63	damaging	0,51	damaging	0,07	deleterious	3,96	23,6	0,07	0,35	disease	0,56	disease	0,79	disease	0,74	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,2	0,8	47,06	9,38	P	0,56	P	0,72	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11608	11608	A	C	MI.18105	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	849	283	K	N	aaA/aaC	8,55	1	0	probably_damaging	1	deleterious	0	neutral	3,17	deleterious	-6,97	deleterious	-4,73	high_impact	4,63	damaging	0,51	damaging	0,07	deleterious	3,89	23,5	0,07	0,35	disease	0,56	disease	0,79	disease	0,74	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,2	0,8	47,06	9,38	P	0,56	P	0,72	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11609	11609	T	A	MI.18106	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	850	284	S	T	Tcg/Acg	0,95	1	0	benign	0,2	neutral	0,07	neutral	4,6	neutral	-0,35	deleterious	-2,82	medium_impact	3,08	neutral	0,67	neutral	0,44	deleterious	3,95	23,6	0,33	0,5	disease	0,64	disease	0,63	disease	0,61	disease	0,64	3	neutral	0,92	neutral	0,44	neutral	-3	deleterious	0,76	medium_impact	-0,15	medium_impact	-0,43	medium_impact	1,92	0,61	0,8	44,23	8,56	P	0,52	P	0,73	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11609	11609	T	C	MI.18107	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	850	284	S	P	Tcg/Ccg	0,95	1	0	probably_damaging	0,94	deleterious	0,01	neutral	4,56	neutral	-2,09	deleterious	-4,71	high_impact	4,12	neutral	0,67	neutral	0,44	deleterious	4,08	23,7	0,04	0,35	disease	0,8	disease	0,83	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,85	low_impact	-1,84	medium_impact	-0,92	high_impact	2,95	0,2	0,8	44,23	8,56	N	0,5	N	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11609	11609	T	G	MI.18108	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	850	284	S	A	Tcg/Gcg	0,95	1	0	benign	0,08	neutral	0,33	neutral	4,67	neutral	0,32	deleterious	-2,79	low_impact	0,96	neutral	0,8	neutral	0,68	deleterious	3,72	23,3	0,35	0,5	disease	0,6	neutral	0,31	neutral	0,4	disease	0,53	1	neutral	0,63	deleterious	0,63	neutral	-6	deleterious	0,73	medium_impact	0,28	medium_impact	0,03	medium_impact	-0,18	0,42	0,8	44,23	8,56	N	0,39	N	0,51	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11610	11610	C	T	MI.18109	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	851	284	S	L	tCg/tTg	3,71	1	0	possibly_damaging	0,74	neutral	0,06	neutral	4,57	neutral	-0,53	deleterious	-5,65	medium_impact	2,69	neutral	0,7	neutral	0,48	deleterious	4,65	24,5	0,08	0,35	disease	0,64	disease	0,83	disease	0,59	disease	0,6	2	neutral	0,95	neutral	0,16	NA	0	deleterious	0,75	low_impact	-1,14	medium_impact	-0,47	medium_impact	1,54	0,33	0,8	44,23	8,56	P	0,6	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8539	8539	C	A	MI.1811	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	174	58	I	M	atC/atA	-0,33	0	0	probably_damaging	0,96	neutral	0,28	neutral	1,22	deleterious	-5,22	deleterious	-2,66	medium_impact	3,44	neutral	0,99	neutral	0,32	deleterious	3,74	23,3	0,46889253	0,85	disease	0,64	neutral	0,27	disease	0,71	neutral	0,22	6	neutral	0,97	neutral	0,16	deleterious	1	deleterious	0,72	low_impact	-2,07	medium_impact	0,06	medium_impact	1,85	0,77	0,85	NA	NA	N	0,5	N	0,57	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11610	11610	C	G	MI.18110	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	851	284	S	W	tCg/tGg	3,71	1	0	probably_damaging	0,99	deleterious	0	neutral	4,54	deleterious	-3,8	deleterious	-6,6	high_impact	4,12	neutral	0,69	neutral	0,44	deleterious	4,37	24,1	0,05	0,35	disease	0,65	disease	0,88	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,59	low_impact	-1,48	high_impact	2,95	0,13	0,8	44,23	8,56	P	0,55	P	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11612	11612	C	A	MI.18111	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	853	285	L	I	Ctc/Atc	-6,42	0	0	probably_damaging	1	neutral	0,09	neutral	4,52	neutral	-1,43	neutral	-1,86	low_impact	1,88	neutral	0,67	neutral	0,53	deleterious	4,12	23,8	0,29	0,45	disease	0,52	disease	0,59	disease	0,57	disease	0,53	1	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,75	low_impact	-3,54	medium_impact	-0,36	medium_impact	0,73	0,53	0,8	47,49	9,22	N	0,37	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11612	11612	C	G	MI.18112	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	853	285	L	V	Ctc/Gtc	-6,42	0	0	probably_damaging	1	deleterious	0	neutral	4,55	neutral	-0,98	deleterious	-2,78	medium_impact	3,12	neutral	0,64	neutral	0,45	deleterious	3,48	23,1	0,23	0,45	disease	0,51	disease	0,58	disease	0,67	disease	0,65	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,75	low_impact	-3,54	low_impact	-1,48	medium_impact	1,96	0,48	0,8	47,49	9,22	N	0,38	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11612	11612	C	T	MI.18113	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	853	285	L	F	Ctc/Ttc	-6,42	0	0	probably_damaging	1	deleterious	0,03	neutral	4,33	deleterious	-3,7	deleterious	-3,73	medium_impact	3,08	neutral	0,65	neutral	0,38	deleterious	4,01	23,6	0,13	0,4	disease	0,69	disease	0,68	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,92	0,52	0,8	47,49	9,22	N	0,3	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11613	11613	T	C	MI.18114	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	854	285	L	P	cTc/cCc	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	4,28	deleterious	-5,88	deleterious	-6,54	high_impact	4,36	damaging	0,54	neutral	0,33	deleterious	3,94	23,5	0,02	0,35	neutral	0,36	disease	0,79	disease	0,77	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,19	0,27	0,8	47,49	9,22	N	0,47	N	0,98	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11613	11613	T	G	MI.18115	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	854	285	L	R	cTc/cGc	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	4,32	deleterious	-3,43	deleterious	-5,59	high_impact	3,55	neutral	0,66	neutral	0,29	deleterious	4,24	23,9	0,01	0,35	disease	0,83	disease	0,83	disease	0,77	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	2,39	0,1	0,8	47,49	9,22	N	0,34	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11613	11613	T	A	MI.18116	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	854	285	L	H	cTc/cAc	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	4,28	deleterious	-5,83	deleterious	-6,54	high_impact	4,36	neutral	0,63	neutral	0,31	deleterious	4,17	23,8	0,04	0,35	disease	0,71	disease	0,77	disease	0,74	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,19	0,23	0,8	47,49	9,22	N	0,4	N	0,96	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11615	11615	A	C	MI.18117	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	856	286	I	L	Att/Ctt	-5,5	0	0	possibly_damaging	0,61	neutral	0,06	neutral	4,68	neutral	0,11	neutral	-1,89	medium_impact	3,5	damaging	0,52	neutral	0,45	deleterious	3,82	23,4	0,27	0,45	neutral	0,36	disease	0,65	disease	0,64	disease	0,66	3	neutral	0,94	neutral	0,23	NA	0	deleterious	0,66	medium_impact	-0,9	medium_impact	-0,47	high_impact	2,34	0,55	0,8	47,28	9,54	P	0,5	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11615	11615	A	G	MI.18118	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	856	286	I	V	Att/Gtt	-5,5	0	0	benign	0,12	neutral	0,15	neutral	4,39	neutral	-1,17	neutral	-0,94	medium_impact	2,01	damaging	0,58	neutral	0,49	deleterious	3,09	22,5	0,34	0,5	neutral	0,47	neutral	0,44	disease	0,61	neutral	0,43	1	neutral	0,83	deleterious	0,52	neutral	-3	deleterious	0,64	medium_impact	0,1	medium_impact	-0,22	medium_impact	0,86	0,49	0,8	47,28	9,54	N	0,44	N	0,75	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11615	11615	A	T	MI.18119	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	856	286	I	F	Att/Ttt	-5,5	0	0	probably_damaging	0,97	deleterious	0	neutral	4,17	deleterious	-4,33	deleterious	-3,78	high_impact	4,13	damaging	0,57	neutral	0,4	deleterious	3,81	23,4	0,04	0,35	disease	0,56	disease	0,79	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,77	low_impact	-2,14	low_impact	-1,48	high_impact	2,96	0,56	0,8	47,28	9,54	N	0,42	N	0,96	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8539	8539	C	G	MI.1812	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	174	58	I	M	atC/atG	-0,33	0	0	probably_damaging	0,96	neutral	0,28	neutral	1,22	deleterious	-5,22	deleterious	-2,66	medium_impact	3,44	neutral	0,99	neutral	0,32	deleterious	3,38	22,9	0,46889253	0,85	disease	0,64	neutral	0,27	disease	0,71	neutral	0,22	6	neutral	0,97	neutral	0,16	deleterious	1	deleterious	0,72	low_impact	-2,07	medium_impact	0,06	medium_impact	1,85	0,77	0,85	NA	NA	N	0,5	N	0,57	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11616	11616	T	G	MI.18120	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	857	286	I	S	aTt/aGt	8,55	1	0	probably_damaging	0,96	deleterious	0	neutral	4,16	deleterious	-5,21	deleterious	-5,67	high_impact	4,47	damaging	0,58	neutral	0,51	deleterious	4,3	24	0,02	0,35	disease	0,65	disease	0,84	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,76	low_impact	-2,01	low_impact	-1,48	high_impact	3,3	0,23	0,8	47,28	9,54	P	0,56	P	0,95	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11616	11616	T	A	MI.18121	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	857	286	I	N	aTt/aAt	8,55	1	0	probably_damaging	0,98	deleterious	0	neutral	4,15	deleterious	-6,38	deleterious	-6,62	high_impact	3,78	damaging	0,54	neutral	0,41	deleterious	4,43	24,2	0,03	0,35	disease	0,66	disease	0,83	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,31	low_impact	-1,48	high_impact	2,61	0,28	0,8	47,28	9,54	P	0,55	P	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11616	11616	T	C	MI.18122	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	857	286	I	T	aTt/aCt	8,55	1	0	probably_damaging	0,91	deleterious	0	neutral	4,17	deleterious	-4,48	deleterious	-4,73	high_impact	3,58	damaging	0,59	neutral	0,41	deleterious	3,4	23	0,03	0,35	neutral	0,42	disease	0,72	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,74	low_impact	-1,66	low_impact	-1,48	high_impact	2,42	0,17	0,8	47,28	9,54	P	0,56	P	0,96	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11617	11617	T	G	MI.18123	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	858	286	I	M	atT/atG	7,4	1	0	probably_damaging	0,97	deleterious	0,01	neutral	4,28	neutral	-2,04	deleterious	-2,83	high_impact	3,67	damaging	0,56	neutral	0,54	deleterious	3,45	23	0,08	0,35	neutral	0,45	disease	0,68	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,72	low_impact	-2,14	medium_impact	-0,92	high_impact	2,51	0,48	0,8	47,28	9,54	P	0,63	P	0,76	polymorphism	1	0,16	rs386829135	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11617	11617	T	A	MI.18124	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	858	286	I	M	atT/atA	7,4	1	0	probably_damaging	0,97	deleterious	0,01	neutral	4,28	neutral	-2,04	deleterious	-2,83	high_impact	3,67	damaging	0,56	neutral	0,54	deleterious	3,73	23,3	0,08	0,35	neutral	0,45	disease	0,68	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,72	low_impact	-2,14	medium_impact	-0,92	high_impact	2,51	0,48	0,8	47,28	9,54	P	0,63	P	0,76	polymorphism	1	0,16	rs386829135	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11618	11618	G	C	MI.18125	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	859	287	A	P	Gca/Cca	-4,35	0	0	probably_damaging	1	deleterious	0	neutral	2,89	deleterious	-9,47	deleterious	-4,73	high_impact	4,63	damaging	0,55	damaging	0,1	deleterious	3,87	23,5	0,01	0,35	disease	0,9	disease	0,87	disease	0,78	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,41	0,8	47,49	9,27	N	0,49	N	0,96	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11618	11618	G	A	MI.18126	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	859	287	A	T	Gca/Aca	-4,35	0	0	probably_damaging	1	deleterious	0	neutral	2,92	deleterious	-7,72	deleterious	-3,78	high_impact	4,08	damaging	0,6	damaging	0,09	deleterious	4,28	24	0,02	0,35	disease	0,68	disease	0,82	disease	0,67	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	2,91	0,72	0,85	47,49	9,27	N	0,34	N	0,82	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11618	11618	G	T	MI.18127	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	859	287	A	S	Gca/Tca	-4,35	0	0	probably_damaging	1	deleterious	0	neutral	2,93	deleterious	-5,78	deleterious	-2,84	high_impact	4,29	damaging	0,59	damaging	0,1	deleterious	3,76	23,3	0,04	0,35	disease	0,77	disease	0,83	disease	0,67	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,12	0,43	0,8	47,49	9,27	N	0,38	N	0,97	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11619	11619	C	G	MI.18128	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	860	287	A	G	gCa/gGa	9,24	1	0	probably_damaging	1	deleterious	0	neutral	2,99	deleterious	-6,06	deleterious	-3,78	high_impact	3,94	damaging	0,51	damaging	0,14	deleterious	4,01	23,6	0,03	0,35	neutral	0,44	disease	0,81	disease	0,67	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,54	low_impact	-1,48	high_impact	2,77	0,54	0,8	47,49	9,27	P	0,57	P	0,79	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11619	11619	C	A	MI.18129	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	860	287	A	E	gCa/gAa	9,24	1	0	probably_damaging	1	deleterious	0	neutral	2,89	deleterious	-10,46	deleterious	-4,73	high_impact	4,63	damaging	0,57	damaging	0,09	deleterious	4,49	24,3	0,02	0,35	disease	0,87	disease	0,88	disease	0,76	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,33	0,8	47,49	9,27	P	0,57	P	0,99	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8540	8540	T	A	MI.1813	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	175	59	C	S	Tgt/Agt	-1,95	0	0	benign	0	neutral	0,77	neutral	1,95	neutral	-0,98	neutral	-1,28	low_impact	1,38	neutral	1	neutral	0,61	deleterious	3,94	23,5	0,60038707	0,85	neutral	0,44	neutral	0,27	disease	0,59	neutral	0,16	7	neutral	0,22	deleterious	0,89	neutral	-6	neutral	0,2	high_impact	2,09	medium_impact	0,59	medium_impact	0,09	0,54	0,85	19,12	7,68	N	0,28	N	0,29	polymorphism	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11619	11619	C	T	MI.18130	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	860	287	A	V	gCa/gTa	9,24	1	0	probably_damaging	1	deleterious	0	neutral	2,95	deleterious	-8,92	deleterious	-3,78	high_impact	4,63	damaging	0,49	damaging	0,08	deleterious	4,49	24,3	0,02	0,35	neutral	0,48	disease	0,85	disease	0,68	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,7	0,85	47,49	9,27	P	0,53	P	0,72	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11621	11621	T	A	MI.18131	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	862	288	Y	N	Tac/Aac	-2,5	0	0	probably_damaging	1	deleterious	0	neutral	4,14	deleterious	-8,25	deleterious	-8,49	high_impact	4,21	damaging	0,44	damaging	0,05	deleterious	4,11	23,7	0,03	0,35	disease	0,81	disease	0,84	disease	0,79	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,04	0,13	0,8	47,49	9,34	N	0,45	N	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11621	11621	T	G	MI.18132	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	862	288	Y	D	Tac/Gac	-2,5	0	0	probably_damaging	1	deleterious	0	neutral	4,14	deleterious	-10,67	deleterious	-9,42	high_impact	3,87	damaging	0,44	damaging	0,06	deleterious	4,07	23,7	0,02	0,35	disease	0,88	disease	0,9	disease	0,85	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,7	0,13	0,8	47,49	9,34	N	0,46	N	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11621	11621	T	C	MI.18133	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	862	288	Y	H	Tac/Cac	-2,5	0	0	probably_damaging	1	deleterious	0	neutral	4,14	deleterious	-7,77	deleterious	-4,72	high_impact	4,56	damaging	0,46	damaging	0,05	deleterious	3,65	23,2	0,06	0,35	disease	0,83	disease	0,81	disease	0,85	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,39	0,19	0,8	47,49	9,34	P	0,52	P	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11622	11622	A	C	MI.18134	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	863	288	Y	S	tAc/tCc	7,4	1	0	probably_damaging	1	deleterious	0,01	neutral	4,17	deleterious	-8,59	deleterious	-8,49	high_impact	3,87	damaging	0,44	damaging	0,08	deleterious	3,65	23,2	0,03	0,35	disease	0,67	disease	0,86	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,54	medium_impact	-0,92	high_impact	2,7	0,12	0,8	47,49	9,34	P	0,66	P	0,95	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11622	11622	A	G	MI.18135	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	863	288	Y	C	tAc/tGc	7,4	1	0	probably_damaging	1	deleterious	0	neutral	4,17	deleterious	-8,85	deleterious	-8,5	high_impact	3,75	damaging	0,43	damaging	0,05	deleterious	3,45	23	0,04	0,35	disease	0,62	disease	0,86	disease	0,82	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	2,58	0,16	0,8	47,49	9,34	P	0,63	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11622	11622	A	T	MI.18136	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	863	288	Y	F	tAc/tTc	7,4	1	0	probably_damaging	1	neutral	0,09	neutral	4,27	deleterious	-4,22	deleterious	-3,78	medium_impact	2,85	damaging	0,47	damaging	0,07	deleterious	3,31	22,9	0,14	0,4	neutral	0,35	disease	0,82	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,36	medium_impact	1,69	0,39	0,8	47,49	9,34	P	0,6	P	0,79	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11624	11624	T	G	MI.18137	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	865	289	S	A	Tct/Gct	-0,43	0,08	0	possibly_damaging	0,64	deleterious	0	neutral	2,51	deleterious	-6,22	deleterious	-2,84	medium_impact	3,46	damaging	0,48	neutral	0,63	deleterious	3,72	23,3	0,09	0,4	disease	0,55	disease	0,56	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,18	deleterious	4	deleterious	0,75	medium_impact	-0,95	low_impact	-1,48	high_impact	2,3	0,39	0,8	47,28	9,28	P	0,52	P	0,36	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11624	11624	T	A	MI.18138	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	865	289	S	T	Tct/Act	-0,43	0,08	0	possibly_damaging	0,85	deleterious	0	neutral	2,47	deleterious	-7,09	deleterious	-2,84	medium_impact	3,23	damaging	0,51	neutral	0,57	deleterious	4,05	23,7	0,08	0,35	disease	0,67	disease	0,66	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,08	deleterious	4	deleterious	0,81	low_impact	-1,43	low_impact	-1,48	high_impact	2,07	0,49	0,8	47,28	9,28	N	0,5	N	0,57	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11624	11624	T	C	MI.18139	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	865	289	S	P	Tct/Cct	-0,43	0,08	0	benign	0,12	deleterious	0	neutral	2,45	deleterious	-8,54	deleterious	-4,73	high_impact	4,26	damaging	0,45	neutral	0,74	deleterious	4,09	23,7	0,03	0,35	disease	0,88	disease	0,81	disease	0,85	disease	0,75	5	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,87	medium_impact	0,1	low_impact	-1,48	high_impact	3,09	0,31	0,8	47,28	9,28	P	0,53	P	0,05	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8540	8540	T	G	MI.1814	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	175	59	C	G	Tgt/Ggt	-1,95	0	0	benign	0	neutral	0,59	neutral	1,93	neutral	-1,88	neutral	-2,28	low_impact	1,38	neutral	1	neutral	0,54	deleterious	4,03	23,6	0,50207441	0,85	disease	0,56	neutral	0,43	disease	0,61	neutral	0,28	4	neutral	0,4	deleterious	0,8	neutral	-6	neutral	0,24	high_impact	2,09	medium_impact	0,38	medium_impact	0,09	0,35	0,85	19,12	7,68	N	0,3	N	0,36	polymorphism	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11625	11625	C	A	MI.18140	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	866	289	S	Y	tCt/tAt	4,63	1	0	probably_damaging	0,98	deleterious	0	neutral	2,44	deleterious	-10,34	deleterious	-5,68	high_impact	4,62	damaging	0,47	neutral	0,5	deleterious	4,11	23,7	0,03	0,35	disease	0,83	disease	0,85	disease	0,77	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,31	low_impact	-1,48	high_impact	3,45	0,23	0,8	47,28	9,28	P	0,61	P	0,95	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11625	11625	C	G	MI.18141	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	866	289	S	C	tCt/tGt	4,63	1	0	probably_damaging	0,98	deleterious	0	neutral	2,49	deleterious	-6,66	deleterious	-4,74	high_impact	4,62	damaging	0,48	neutral	0,51	deleterious	3,67	23,2	0,04	0,35	disease	0,76	disease	0,77	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,31	low_impact	-1,48	high_impact	3,45	0,27	0,8	47,28	9,28	P	0,61	P	0,57	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11625	11625	C	T	MI.18142	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	866	289	S	F	tCt/tTt	4,63	1	0	probably_damaging	0,98	deleterious	0	neutral	2,44	deleterious	-9,94	deleterious	-5,68	high_impact	4,26	damaging	0,48	neutral	0,57	deleterious	4,22	23,9	0,03	0,35	disease	0,77	disease	0,88	disease	0,76	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,31	low_impact	-1,48	high_impact	3,09	0,17	0,8	47,28	9,28	P	0,57	P	0,94	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11627	11627	T	G	MI.18143	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	868	290	S	A	Tca/Gca	-8,72	0	0	possibly_damaging	0,64	deleterious	0	neutral	3,97	deleterious	-3,71	deleterious	-2,84	high_impact	4,29	damaging	0,48	neutral	0,52	deleterious	3,75	23,3	0,07	0,35	disease	0,51	disease	0,56	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	5	deleterious	0,74	medium_impact	-0,95	low_impact	-1,48	high_impact	3,12	0,38	0,8	47,49	9,35	P	0,55	P	0,51	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11627	11627	T	A	MI.18144	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	868	290	S	T	Tca/Aca	-8,72	0	0	possibly_damaging	0,85	deleterious	0	neutral	4,51	neutral	-0,37	deleterious	-2,84	high_impact	4,29	damaging	0,55	neutral	0,45	deleterious	3,87	23,5	0,11	0,4	disease	0,71	disease	0,66	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,08	deleterious	5	deleterious	0,81	low_impact	-1,43	low_impact	-1,48	high_impact	3,12	0,46	0,8	47,49	9,35	N	0,48	N	0,73	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11627	11627	T	C	MI.18145	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	868	290	S	P	Tca/Cca	-8,72	0	0	benign	0,12	deleterious	0	neutral	3,91	deleterious	-6	deleterious	-4,72	high_impact	4,29	damaging	0,45	neutral	0,48	deleterious	4,05	23,7	0,03	0,35	disease	0,82	disease	0,81	disease	0,8	disease	0,71	4	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,87	medium_impact	0,1	low_impact	-1,48	high_impact	3,12	0,29	0,8	47,49	9,35	N	0,48	N	0,99	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11628	11628	C	G	MI.18146	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	869	290	S	W	tCa/tGa	5,78	1	0	probably_damaging	0,99	deleterious	0	neutral	3,9	deleterious	-9,39	deleterious	-6,62	high_impact	4,63	damaging	0,55	neutral	0,51	deleterious	4,42	24,2	0,03	0,35	disease	0,95	disease	0,88	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,59	low_impact	-1,48	high_impact	3,45	0,13	0,8	47,49	9,35	P	0,58	P	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11628	11628	C	T	MI.18147	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	869	290	S	L	tCa/tTa	5,78	1	0	probably_damaging	0,91	deleterious	0	neutral	3,91	deleterious	-6,25	deleterious	-5,67	high_impact	4,63	damaging	0,47	neutral	0,44	deleterious	4,67	24,5	0,02	0,35	neutral	0,43	disease	0,86	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,77	low_impact	-1,66	low_impact	-1,48	high_impact	3,45	0,39	0,8	47,49	9,35	P	0,62	P	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11630	11630	A	G	MI.18148	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	871	291	I	V	Atc/Gtc	-11,94	0	0	benign	0	neutral	1	neutral	4,34	neutral	-0,26	neutral	0,84	neutral_impact	-1,59	neutral	0,79	neutral	0,94	neutral	-1,51	0	0,45	0,55	neutral	0,37	neutral	0,09	neutral	0,35	neutral	0,22	6	neutral	0	deleterious	1	neutral	-6	neutral	0,13	high_impact	2,1	high_impact	1,88	low_impact	-2,7	0,38	0,8	44,88	8,84	N	0,28	N	0	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11630	11630	A	C	MI.18149	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	871	291	I	L	Atc/Ctc	-11,94	0	0	benign	0,05	neutral	0,07	neutral	4,27	neutral	-2,32	neutral	-1,89	medium_impact	1,98	neutral	0,71	neutral	0,54	deleterious	1,97	16,02	0,17	0,45	neutral	0,35	disease	0,59	disease	0,64	disease	0,69	4	neutral	0,93	deleterious	0,51	neutral	-3	neutral	0,21	medium_impact	0,48	medium_impact	-0,43	medium_impact	0,83	0,49	0,8	44,88	8,84	N	0,46	N	0,14	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8540	8540	T	C	MI.1815	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	175	59	C	R	Tgt/Cgt	-1,95	0	0	benign	0	neutral	0,39	neutral	1,94	neutral	-1,78	neutral	-1,56	low_impact	1,38	neutral	0,99	neutral	0,54	deleterious	3,72	23,3	0,5577664	0,85	disease	0,58	disease	0,51	disease	0,67	disease	0,63	3	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,26	high_impact	2,09	medium_impact	0,18	medium_impact	0,09	0,26	0,85	19,12	7,68	N	0,39	N	0,33	disease_causing	1	0,08	rs878852987	Uncertain significance	not_provided	RCV000224948.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	11630	11630	A	T	MI.18150	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	871	291	I	F	Atc/Ttc	-11,94	0	0	possibly_damaging	0,55	deleterious	0	neutral	4,07	deleterious	-4,74	deleterious	-3,79	medium_impact	2,33	neutral	0,7	neutral	0,54	deleterious	2,19	17,42	0,05	0,35	neutral	0,39	disease	0,81	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,23	deleterious	4	neutral	0,41	medium_impact	-0,8	low_impact	-1,48	medium_impact	1,18	0,56	0,8	44,88	8,84	N	0,4	N	0,31	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11631	11631	T	A	MI.18151	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	872	291	I	N	aTc/aAc	1,87	0,99	0	possibly_damaging	0,8	deleterious	0	neutral	4,05	deleterious	-6,05	deleterious	-5,73	medium_impact	2,88	neutral	0,68	neutral	0,54	deleterious	4,31	24	0,04	0,35	disease	0,78	disease	0,85	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,1	deleterious	4	deleterious	0,74	low_impact	-1,28	low_impact	-1,48	medium_impact	1,72	0,24	0,8	44,88	8,84	N	0,47	N	0,47	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11631	11631	T	C	MI.18152	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	872	291	I	T	aTc/aCc	1,87	0,99	0	benign	0,18	deleterious	0	neutral	4,08	deleterious	-3,79	deleterious	-2,94	medium_impact	2,88	neutral	0,72	neutral	0,5	neutral	1,66	14,2	0,04	0,35	neutral	0,4	disease	0,53	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,41	deleterious	1	neutral	0,28	medium_impact	-0,1	low_impact	-1,48	medium_impact	1,72	0,19	0,8	44,88	8,84	N	0,47	N	0,18	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11631	11631	T	G	MI.18153	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	872	291	I	S	aTc/aGc	1,87	0,99	0	benign	0,41	deleterious	0	neutral	4,08	deleterious	-4,34	deleterious	-4,79	medium_impact	2,88	neutral	0,7	neutral	0,55	deleterious	2,59	20,1	0,03	0,35	disease	0,65	disease	0,8	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,46	medium_impact	-0,57	low_impact	-1,48	medium_impact	1,72	0,15	0,8	44,88	8,84	N	0,46	N	0,32	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11632	11632	C	G	MI.18154	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	873	291	I	M	atC/atG	7,4	1	0	possibly_damaging	0,55	deleterious	0	neutral	4,14	deleterious	-3,19	neutral	-1,94	medium_impact	2,52	neutral	0,74	neutral	0,48	deleterious	1,84	15,23	0,11	0,4	disease	0,56	disease	0,63	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,23	deleterious	4	deleterious	0,54	medium_impact	-0,8	low_impact	-1,48	medium_impact	1,37	0,61	0,8	44,88	8,84	P	0,61	P	0,11	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11632	11632	C	A	MI.18155	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	873	291	I	M	atC/atA	7,4	1	0	possibly_damaging	0,55	deleterious	0	neutral	4,14	deleterious	-3,19	neutral	-1,94	medium_impact	2,52	neutral	0,74	neutral	0,48	deleterious	2,24	17,78	0,11	0,4	disease	0,56	disease	0,63	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,23	deleterious	4	deleterious	0,54	medium_impact	-0,8	low_impact	-1,48	medium_impact	1,37	0,61	0,8	44,88	8,84	P	0,61	P	0,11	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11633	11633	A	C	MI.18156	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	874	292	S	R	Agc/Cgc	-20	0	0	probably_damaging	1	deleterious	0,01	neutral	4,34	deleterious	-4,3	deleterious	-4,58	high_impact	4,17	neutral	0,72	damaging	0,13	deleterious	3,86	23,5	0,03	0,35	disease	0,51	disease	0,89	disease	0,77	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,54	medium_impact	-0,92	high_impact	3	0,38	0,8	46,62	9,31	N	0,39	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11633	11633	A	T	MI.18157	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	874	292	S	C	Agc/Tgc	-20	0	0	probably_damaging	1	neutral	0,11	neutral	4,33	deleterious	-6,39	deleterious	-4,65	medium_impact	2,79	neutral	0,7	damaging	0,1	deleterious	3,43	23	0,05	0,35	disease	0,91	disease	0,82	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,31	medium_impact	1,63	0,32	0,8	46,62	9,31	N	0,28	N	1	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11633	11633	A	G	MI.18158	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	874	292	S	G	Agc/Ggc	-20	0	0	probably_damaging	1	neutral	0,36	neutral	4,42	deleterious	-3,15	deleterious	-3,37	low_impact	1,72	neutral	0,73	neutral	0,31	deleterious	2,55	19,77	0,12	0,4	neutral	0,5	disease	0,58	disease	0,51	neutral	0,33	3	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	0,06	medium_impact	0,58	0,52	0,8	46,62	9,31	N	0,3	N	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11634	11634	G	A	MI.18159	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	875	292	S	N	aGc/aAc	4,63	1	0	probably_damaging	1	deleterious	0,03	neutral	4,36	deleterious	-3,92	deleterious	-2,71	medium_impact	3,07	neutral	0,73	damaging	0,14	deleterious	3,65	23,2	0,21	0,45	neutral	0,5	disease	0,76	disease	0,68	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,78	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,91	0,29	0,8	46,62	9,31	N	0,52	P	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8541	8541	G	C	MI.1816	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	176	59	C	S	tGt/tCt	7,53	1	0	benign	0	neutral	0,77	neutral	1,95	neutral	-0,98	neutral	-1,28	low_impact	1,38	neutral	1	neutral	0,61	deleterious	0,49	7,39	0,60038707	0,85	neutral	0,44	neutral	0,27	disease	0,59	neutral	0,16	7	neutral	0,22	deleterious	0,89	neutral	-6	neutral	0,2	high_impact	2,09	medium_impact	0,59	medium_impact	0,09	0,54	0,85	19,12	7,68	N	0,51	P	0,29	polymorphism	0,72	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11634	11634	G	C	MI.18160	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	875	292	S	T	aGc/aCc	4,63	1	0	probably_damaging	1	neutral	0,19	neutral	4,4	deleterious	-3,99	deleterious	-2,79	medium_impact	3,07	neutral	0,7	damaging	0,13	deleterious	3,48	23,1	0,14	0,4	neutral	0,48	disease	0,68	disease	0,67	disease	0,65	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,15	medium_impact	1,91	0,57	0,8	46,62	9,31	P	0,55	P	0,73	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11634	11634	G	T	MI.18161	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	875	292	S	I	aGc/aTc	4,63	1	0	probably_damaging	1	deleterious	0,03	neutral	4,35	deleterious	-4,81	deleterious	-5,59	medium_impact	2,82	neutral	0,71	damaging	0,14	deleterious	4,18	23,8	0,03	0,35	disease	0,76	disease	0,92	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,86	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,66	0,28	0,8	46,62	9,31	N	0,44	N	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11636	11636	C	A	MI.18162	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	877	293	H	N	Cac/Aac	-1,35	0	0	probably_damaging	1	deleterious	0	neutral	4,35	neutral	-1,59	deleterious	-6,61	high_impact	4,64	damaging	0,51	damaging	0,1	deleterious	3,93	23,5	0,16	0,45	disease	0,59	disease	0,84	disease	0,77	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,46	0,23	0,8	47,28	9,28	P	0,56	P	0,97	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11636	11636	C	T	MI.18163	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	877	293	H	Y	Cac/Tac	-1,35	0	0	probably_damaging	1	deleterious	0	neutral	4,19	deleterious	-5,66	deleterious	-5,66	high_impact	4,64	damaging	0,57	damaging	0,09	deleterious	3,79	23,4	0,06	0,35	neutral	0,41	disease	0,89	disease	0,79	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	3,46	0,24	0,8	47,28	9,28	P	0,53	P	0,99	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11636	11636	C	G	MI.18164	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	877	293	H	D	Cac/Gac	-1,35	0	0	probably_damaging	1	deleterious	0	neutral	4,25	neutral	-2,99	deleterious	-8,5	high_impact	4,64	neutral	0,61	damaging	0,1	deleterious	3,89	23,5	0,05	0,35	disease	0,68	disease	0,9	disease	0,84	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,46	0,21	0,8	47,28	9,28	P	0,61	P	0,97	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11637	11637	A	C	MI.18165	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	878	293	H	P	cAc/cCc	5,55	1	0	probably_damaging	1	deleterious	0	neutral	4,2	deleterious	-4,99	deleterious	-9,44	high_impact	4,64	damaging	0,56	damaging	0,1	deleterious	3,28	22,8	0,03	0,35	disease	0,73	disease	0,9	disease	0,86	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,46	0,16	0,8	47,28	9,28	P	0,68	P	0,95	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11637	11637	A	G	MI.18166	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	878	293	H	R	cAc/cGc	5,55	1	0	probably_damaging	1	deleterious	0	neutral	4,23	deleterious	-3,49	deleterious	-7,55	high_impact	4,64	damaging	0,55	damaging	0,09	deleterious	3,04	22,4	0,06	0,35	neutral	0,46	disease	0,89	disease	0,82	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	3,46	0,28	0,8	47,28	9,28	P	0,71	P	0,97	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11637	11637	A	T	MI.18167	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	878	293	H	L	cAc/cTc	5,55	1	0	probably_damaging	1	deleterious	0	neutral	4,2	deleterious	-4,65	deleterious	-10,38	high_impact	4,64	damaging	0,53	damaging	0,09	deleterious	3,96	23,6	0,03	0,35	disease	0,76	disease	0,93	disease	0,78	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,46	0,23	0,8	47,28	9,28	P	0,67	P	0,96	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11638	11638	C	G	MI.18168	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	879	293	H	Q	caC/caG	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,54	neutral	-0,44	deleterious	-7,55	high_impact	4,29	damaging	0,57	damaging	0,09	deleterious	3,61	23,2	0,11	0,4	neutral	0,44	disease	0,85	disease	0,77	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	3,12	0,25	0,8	47,28	9,28	P	0,66	P	0,93	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11638	11638	C	A	MI.18169	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	879	293	H	Q	caC/caA	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,54	neutral	-0,44	deleterious	-7,55	high_impact	4,29	damaging	0,57	damaging	0,09	deleterious	4,02	23,6	0,11	0,4	neutral	0,44	disease	0,85	disease	0,77	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	3,12	0,25	0,8	47,28	9,28	P	0,66	P	0,93	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8541	8541	G	A	MI.1817	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	176	59	C	Y	tGt/tAt	7,53	1	0	benign	0	neutral	1	neutral	2,81	neutral	2,59	neutral	5,76	neutral_impact	-2,05	neutral	0,99	neutral	0,86	deleterious	0,49	7,38	0,56663707	0,85	neutral	0,12	neutral	0,1	neutral	0,4	neutral	0,04	9	neutral	0	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,09	high_impact	1,98	low_impact	-2,85	0,49	0,85	19,12	7,68	N	0,53	P	0,16	polymorphism	0,55	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11639	11639	A	C	MI.18170	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	880	294	M	L	Ata/Cta	-3,19	0	0	probably_damaging	0,98	deleterious	0,01	neutral	4,63	neutral	-0,06	deleterious	-2,83	high_impact	3,65	neutral	0,69	damaging	0,1	deleterious	3,09	22,5	0,18	0,45	disease	0,63	disease	0,87	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,67	low_impact	-2,31	medium_impact	-0,92	high_impact	2,49	0,38	0,8	47,28	9,16	N	0,32	N	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11639	11639	A	T	MI.18171	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	880	294	M	L	Ata/Tta	-3,19	0	0	probably_damaging	0,98	deleterious	0,01	neutral	4,63	neutral	-0,06	deleterious	-2,83	high_impact	3,65	neutral	0,69	damaging	0,1	deleterious	3,19	22,7	0,18	0,45	disease	0,63	disease	0,87	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,67	low_impact	-2,31	medium_impact	-0,92	high_impact	2,49	0,38	0,8	47,28	9,16	N	0,32	N	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11639	11639	A	G	MI.18172	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	880	294	M	V	Ata/Gta	-3,19	0	0	probably_damaging	0,99	deleterious	0	neutral	4,43	neutral	-1,33	deleterious	-3,77	high_impact	3,65	neutral	0,65	damaging	0,13	deleterious	2,56	19,83	0,11	0,4	disease	0,69	disease	0,88	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,72	low_impact	-2,59	low_impact	-1,48	high_impact	2,49	0,38	0,8	47,28	9,16	N	0,32	N	0,96	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11640	11640	T	A	MI.18173	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	881	294	M	K	aTa/aAa	6,7	1	0	probably_damaging	1	deleterious	0	neutral	4,29	deleterious	-4,36	deleterious	-5,65	high_impact	4,28	neutral	0,68	damaging	0,12	deleterious	4,04	23,7	0,03	0,35	disease	0,59	disease	0,92	disease	0,8	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	3,11	0,2	0,8	47,28	9,16	P	0,65	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11640	11640	T	C	MI.18174	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	881	294	M	T	aTa/aCa	6,7	1	0	probably_damaging	1	deleterious	0	neutral	4,32	deleterious	-3,09	deleterious	-5,65	high_impact	4,62	neutral	0,79	damaging	0,14	deleterious	3,02	22,3	0,04	0,35	neutral	0,41	disease	0,87	disease	0,74	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,19	0,8	47,28	9,16	P	0,59	P	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11641	11641	A	C	MI.18175	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	882	294	M	I	atA/atC	7,4	1	0	probably_damaging	0,99	neutral	0,05	neutral	4,5	neutral	-0,79	deleterious	-3,78	high_impact	3,82	neutral	0,69	damaging	0,14	deleterious	3,45	23	0,11	0,4	disease	0,77	disease	0,9	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	-0,52	high_impact	2,65	0,34	0,8	47,28	9,16	P	0,66	P	0,95	disease_causing	1	0,18	rs2853494	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11641	11641	A	T	MI.18176	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	882	294	M	I	atA/atT	7,4	1	0	probably_damaging	0,99	neutral	0,05	neutral	4,5	neutral	-0,79	deleterious	-3,78	high_impact	3,82	neutral	0,69	damaging	0,14	deleterious	3,56	23,1	0,11	0,4	disease	0,77	disease	0,9	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	-0,52	high_impact	2,65	0,34	0,8	47,28	9,16	P	0,66	P	0,95	disease_causing	1	0,18	rs2853494	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11642	11642	G	A	MI.18177	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	883	295	A	T	Gcc/Acc	0,03	0,78	0	probably_damaging	0,91	deleterious	0,03	neutral	4,58	neutral	-1,59	deleterious	-3,02	medium_impact	2,25	neutral	0,65	damaging	0,1	deleterious	4,31	24	0,07	0,35	disease	0,51	disease	0,73	disease	0,64	disease	0,7	4	deleterious	0,99	neutral	0,06	deleterious	5	deleterious	0,82	low_impact	-1,66	medium_impact	-0,64	medium_impact	1,1	0,73	0,85	14,81	17,1	N	0,32	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11642	11642	G	T	MI.18178	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	883	295	A	S	Gcc/Tcc	0,03	0,78	0	benign	0,33	neutral	0,47	neutral	4,81	neutral	0,29	neutral	-1,69	low_impact	0,92	neutral	0,73	damaging	0,22	deleterious	3,74	23,3	0,15	0,4	neutral	0,39	disease	0,72	neutral	0,41	neutral	0,37	3	neutral	0,44	deleterious	0,57	neutral	-6	deleterious	0,8	medium_impact	-0,43	medium_impact	0,17	medium_impact	-0,22	0,43	0,8	14,81	17,1	N	0,26	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11642	11642	G	C	MI.18179	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	883	295	A	P	Gcc/Ccc	0,03	0,78	0	probably_damaging	0,98	deleterious	0,01	neutral	4,56	neutral	-2,9	deleterious	-3,6	medium_impact	3,35	damaging	0,52	damaging	0,06	deleterious	3,87	23,5	0,03	0,35	disease	0,58	disease	0,94	disease	0,76	disease	0,83	7	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,9	low_impact	-2,31	medium_impact	-0,92	high_impact	2,19	0,29	0,8	14,81	17,1	N	0,37	N	0,95	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8541	8541	G	T	MI.1818	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	176	59	C	F	tGt/tTt	7,53	1	0	benign	0	neutral	0,68	neutral	2,03	neutral	-0,13	neutral	2,56	low_impact	1,38	neutral	1	neutral	0,7	deleterious	0,37	6,35	0,51545309	0,85	neutral	0,27	neutral	0,41	disease	0,51	neutral	0,17	7	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,18	high_impact	2,09	medium_impact	0,48	medium_impact	0,09	0,42	0,85	19,12	7,68	N	0,51	P	0,16	disease_causing	0,68	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11643	11643	C	A	MI.18180	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	884	295	A	D	gCc/gAc	6,01	1	0	probably_damaging	0,96	deleterious	0	neutral	4,57	deleterious	-4,37	deleterious	-3,79	medium_impact	3,35	damaging	0,57	damaging	0,07	deleterious	4,7	24,6	0,02	0,35	neutral	0,37	disease	0,94	disease	0,75	disease	0,82	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,86	low_impact	-2,01	low_impact	-1,48	high_impact	2,19	0,2	0,8	14,81	17,1	P	0,52	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11643	11643	C	G	MI.18181	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	884	295	A	G	gCc/gGc	6,01	1	0	possibly_damaging	0,86	neutral	1	neutral	5,81	neutral	5,97	neutral	-0,03	neutral_impact	-0,56	neutral	0,64	neutral	0,53	neutral	1,32	12,39	0,13	0,4	disease	0,52	neutral	0,18	neutral	0,41	neutral	0,2	6	neutral	0,85	deleterious	0,57	neutral	-3	deleterious	0,71	low_impact	-1,46	high_impact	1,88	low_impact	-1,68	0,52	0,8	14,81	17,1	P	0,57	P	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11643	11643	C	T	MI.18182	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	884	295	A	V	gCc/gTc	6,01	1	0	probably_damaging	0,94	deleterious	0	neutral	4,56	neutral	-2,98	deleterious	-3,41	medium_impact	3,35	neutral	0,63	damaging	0,09	deleterious	4,52	24,3	0,04	0,35	disease	0,68	disease	0,87	disease	0,65	disease	0,77	5	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,87	low_impact	-1,84	low_impact	-1,48	high_impact	2,19	0,71	0,85	14,81	17,1	P	0,58	P	0,78	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11645	11645	C	A	MI.18183	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	886	296	L	I	Ctc/Atc	-11,71	0	0	probably_damaging	1	neutral	0,34	neutral	4,54	neutral	-0,98	neutral	-1,89	medium_impact	2,17	neutral	0,7	damaging	0,13	deleterious	4,17	23,8	0,25	0,45	disease	0,62	disease	0,64	disease	0,53	neutral	0,37	3	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	0,04	medium_impact	1,02	0,4	0,8	47,28	9,18	N	0,29	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11645	11645	C	T	MI.18184	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	886	296	L	F	Ctc/Ttc	-11,71	0	0	probably_damaging	1	neutral	0,19	neutral	4,72	neutral	0,46	deleterious	-3,76	medium_impact	2,12	neutral	0,71	damaging	0,13	deleterious	4,03	23,7	0,23	0,45	disease	0,89	disease	0,78	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	-0,15	medium_impact	0,97	0,41	0,8	47,28	9,18	N	0,26	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11645	11645	C	G	MI.18185	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	886	296	L	V	Ctc/Gtc	-11,71	0	0	probably_damaging	1	neutral	0,06	neutral	4,53	neutral	-1,04	deleterious	-2,84	medium_impact	2,52	neutral	0,65	damaging	0,11	deleterious	3,52	23,1	0,24	0,45	disease	0,7	disease	0,68	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,37	0,5	0,8	47,28	9,18	N	0,28	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11646	11646	T	A	MI.18186	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	887	296	L	H	cTc/cAc	0,72	0,17	0	probably_damaging	1	deleterious	0	neutral	4,43	deleterious	-3,92	deleterious	-6,62	high_impact	3,94	neutral	0,65	damaging	0,1	deleterious	4,22	23,9	0,04	0,35	disease	0,7	disease	0,82	disease	0,72	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,77	0,24	0,8	47,28	9,18	N	0,36	N	0,96	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11646	11646	T	C	MI.18187	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	887	296	L	P	cTc/cCc	0,72	0,17	0	probably_damaging	1	deleterious	0,01	neutral	4,43	deleterious	-4,51	deleterious	-6,62	high_impact	3,94	neutral	0,6	damaging	0,1	deleterious	4	23,6	0,03	0,35	neutral	0,36	disease	0,84	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-3,54	medium_impact	-0,92	high_impact	2,77	0,45	0,8	47,28	9,18	N	0,39	N	0,98	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11646	11646	T	G	MI.18188	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	887	296	L	R	cTc/cGc	0,72	0,17	0	probably_damaging	1	deleterious	0	neutral	4,43	deleterious	-3,95	deleterious	-5,67	high_impact	4,29	damaging	0,6	damaging	0,09	deleterious	4,29	24	0,02	0,35	neutral	0,47	disease	0,89	disease	0,74	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,12	0,12	0,8	47,28	9,18	N	0,45	N	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11648	11648	G	C	MI.18189	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	889	297	V	L	Gta/Cta	-10,79	0	0	probably_damaging	1	neutral	0,07	neutral	4,58	neutral	-0,71	deleterious	-2,83	medium_impact	2,59	neutral	0,65	damaging	0,09	deleterious	3,6	23,2	0,15	0,4	disease	0,53	disease	0,75	disease	0,62	disease	0,57	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,43	medium_impact	1,44	0,32	0,8	47,06	9,36	N	0,28	N	0,74	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8542	8542	T	A	MI.1819	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	177	59	C	W	tgT/tgA	0,13	0,97	0	benign	0,01	neutral	0,18	neutral	1,94	neutral	-2,56	neutral	1,76	low_impact	1,38	neutral	0,99	neutral	0,51	deleterious	4,3	24	0,46155204	0,85	disease	0,62	neutral	0,49	disease	0,69	disease	0,62	2	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,27	medium_impact	1,14	medium_impact	-0,08	medium_impact	0,09	0,32	0,85	19,12	7,68	N	0,54	P	0,12	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11648	11648	G	T	MI.18190	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	889	297	V	L	Gta/Tta	-10,79	0	0	probably_damaging	1	neutral	0,07	neutral	4,58	neutral	-0,71	deleterious	-2,83	medium_impact	2,59	neutral	0,65	damaging	0,09	deleterious	3,76	23,4	0,15	0,4	disease	0,53	disease	0,75	disease	0,62	disease	0,57	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,43	medium_impact	1,44	0,32	0,8	47,06	9,36	N	0,28	N	0,74	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11648	11648	G	A	MI.18191	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	889	297	V	M	Gta/Ata	-10,79	0	0	probably_damaging	1	neutral	0,09	neutral	4,45	neutral	0,08	deleterious	-2,84	medium_impact	2,29	neutral	0,73	damaging	0,14	deleterious	3,8	23,4	0,14	0,4	disease	0,79	disease	0,73	disease	0,59	disease	0,52	0	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,36	medium_impact	1,14	0,54	0,8	47,06	9,36	N	0,26	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11649	11649	T	G	MI.18192	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	890	297	V	G	gTa/gGa	7,4	1	0	probably_damaging	1	deleterious	0	neutral	4,38	deleterious	-4,19	deleterious	-6,62	medium_impact	3,35	neutral	0,63	damaging	0,11	deleterious	3,89	23,5	0,02	0,35	disease	0,61	disease	0,83	disease	0,66	disease	0,69	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	2,19	0,33	0,8	47,06	9,36	P	0,54	P	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11649	11649	T	A	MI.18193	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	890	297	V	E	gTa/gAa	7,4	1	0	probably_damaging	1	deleterious	0	neutral	4,38	deleterious	-4,32	deleterious	-5,68	high_impact	4,38	neutral	0,68	damaging	0,11	deleterious	4,73	24,6	0,01	0,35	neutral	0,37	disease	0,89	disease	0,77	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	3,21	0,15	0,8	47,06	9,36	P	0,62	P	0,97	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11649	11649	T	C	MI.18194	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	890	297	V	A	gTa/gCa	7,4	1	0	probably_damaging	1	neutral	0,05	neutral	4,46	neutral	-1,94	deleterious	-3,78	medium_impact	2,7	neutral	0,65	damaging	0,13	deleterious	3,64	23,2	0,05	0,35	neutral	0,39	disease	0,58	disease	0,63	disease	0,55	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,55	0,1	0,8	47,06	9,36	P	0,64	P	0,54	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11651	11651	G	A	MI.18195	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	892	298	V	M	Gta/Ata	-3,42	0	0	possibly_damaging	0,66	neutral	0,16	neutral	4,81	neutral	-0,89	neutral	-1,79	low_impact	0,84	neutral	0,77	neutral	0,57	deleterious	2,2	17,5	0,25	0,45	disease	0,56	neutral	0,47	disease	0,56	disease	0,65	3	neutral	0,86	neutral	0,25	neutral	-3	deleterious	0,54	medium_impact	-0,99	medium_impact	-0,2	medium_impact	-0,3	0,83	0,85	28,54	8,66	N	0,33	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11651	11651	G	C	MI.18196	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	892	298	V	L	Gta/Cta	-3,42	0	0	benign	0,05	neutral	0,78	neutral	4,86	neutral	0,81	neutral	-1,14	neutral_impact	0,06	neutral	0,73	neutral	0,57	neutral	1,68	14,29	0,2	0,45	neutral	0,4	neutral	0,41	neutral	0,34	neutral	0,46	1	neutral	0,14	deleterious	0,87	neutral	-6	neutral	0,18	medium_impact	0,48	medium_impact	0,51	low_impact	-1,07	0,5	0,8	28,54	8,66	N	0,28	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11651	11651	G	T	MI.18197	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	892	298	V	L	Gta/Tta	-3,42	0	0	benign	0,05	neutral	0,78	neutral	4,86	neutral	0,81	neutral	-1,14	neutral_impact	0,06	neutral	0,73	neutral	0,57	deleterious	1,84	15,21	0,2	0,45	neutral	0,4	neutral	0,41	neutral	0,34	neutral	0,46	1	neutral	0,14	deleterious	0,87	neutral	-6	neutral	0,18	medium_impact	0,48	medium_impact	0,51	low_impact	-1,07	0,5	0,8	28,54	8,66	N	0,27	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11652	11652	T	G	MI.18198	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	893	298	V	G	gTa/gGa	3,02	0,35	0	benign	0,34	deleterious	0,03	neutral	4,59	deleterious	-3,53	deleterious	-5,33	medium_impact	2,29	neutral	0,71	neutral	0,51	deleterious	3,47	23	0,03	0,35	disease	0,82	disease	0,67	disease	0,58	disease	0,69	4	neutral	0,97	neutral	0,35	deleterious	1	deleterious	0,6	medium_impact	-0,45	medium_impact	-0,64	medium_impact	1,14	0,24	0,8	28,54	8,66	N	0,36	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11652	11652	T	C	MI.18199	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	893	298	V	A	gTa/gCa	3,02	0,35	0	benign	0,18	neutral	0,57	neutral	4,65	neutral	-0,99	neutral	-2,37	neutral_impact	0,74	neutral	0,68	neutral	0,67	neutral	-0,18	1,23	0,13	0,4	disease	0,57	neutral	0,19	neutral	0,35	neutral	0,47	1	neutral	0,32	deleterious	0,7	neutral	-6	neutral	0,31	medium_impact	-0,1	medium_impact	0,27	medium_impact	-0,39	0,21	0,8	28,54	8,66	N	0,34	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8611	8611	C	A	MI.182	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	85	29	L	M	Cta/Ata	-6,12	0	0	probably_damaging	1	neutral	0,44	neutral	4,29	neutral	-1,85	neutral	-0,6	low_impact	1,49	neutral	0,87	neutral	0,83	deleterious	2,22	17,67	0,38	0,65	disease	0,64	neutral	0,14	neutral	0,18	neutral	0,4	2	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,23	medium_impact	0,18	0,65	0,9	17,26	17,02	N	0,45	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8542	8542	T	G	MI.1820	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	177	59	C	W	tgT/tgG	0,13	0,97	0	benign	0,01	neutral	0,18	neutral	1,94	neutral	-2,56	neutral	1,76	low_impact	1,38	neutral	0,99	neutral	0,51	deleterious	3,95	23,6	0,46155204	0,85	disease	0,62	neutral	0,49	disease	0,69	disease	0,62	2	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,27	medium_impact	1,14	medium_impact	-0,08	medium_impact	0,09	0,32	0,85	19,12	7,68	N	0,51	P	0,12	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11652	11652	T	A	MI.18200	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	893	298	V	E	gTa/gAa	3,02	0,35	0	possibly_damaging	0,47	deleterious	0,02	neutral	4,56	deleterious	-4,3	deleterious	-4,7	medium_impact	2,63	neutral	0,72	neutral	0,5	deleterious	4,52	24,3	0,03	0,35	disease	0,7	disease	0,84	disease	0,69	disease	0,78	6	neutral	0,98	neutral	0,28	deleterious	4	deleterious	0,75	medium_impact	-0,67	medium_impact	-0,75	medium_impact	1,48	0,16	0,8	28,54	8,66	N	0,38	N	0,94	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11654	11654	A	C	MI.18201	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	895	299	T	P	Aca/Cca	-6,88	0	0	benign	0,11	deleterious	0,03	neutral	4,58	neutral	-2,36	neutral	-1,61	low_impact	1,58	neutral	0,68	neutral	0,47	neutral	1,68	14,3	0,04	0,35	disease	0,79	disease	0,81	disease	0,66	disease	0,77	5	neutral	0,97	neutral	0,46	neutral	-2	neutral	0,34	medium_impact	0,14	medium_impact	-0,64	medium_impact	0,44	0,33	0,8	31,15	23,21	N	0,29	N	0,7	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11654	11654	A	G	MI.18202	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	895	299	T	A	Aca/Gca	-6,88	0	0	benign	0	neutral	1	neutral	4,69	neutral	0,69	neutral	1,05	neutral_impact	-1,48	neutral	0,76	neutral	0,99	neutral	-1,11	0,01	0,19	0,45	neutral	0,37	neutral	0,08	neutral	0,23	neutral	0,25	5	neutral	0	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,1	high_impact	1,88	low_impact	-2,59	0,27	0,8	31,15	23,21	N	0,32	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11654	11654	A	T	MI.18203	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	895	299	T	S	Aca/Tca	-6,88	0	0	benign	0,04	neutral	0,27	neutral	4,63	neutral	-0,4	neutral	-0,45	neutral_impact	-0,61	neutral	0,75	neutral	0,83	deleterious	0,06	3,22	0,29	0,45	neutral	0,43	neutral	0,31	neutral	0,27	neutral	0,47	1	neutral	0,71	deleterious	0,62	neutral	-6	neutral	0,14	medium_impact	0,58	medium_impact	-0,04	low_impact	-1,73	0,55	0,8	31,15	23,21	N	0,42	N	0,37	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11655	11655	C	A	MI.18204	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	896	299	T	K	aCa/aAa	0,72	0	0	benign	0,06	deleterious	0,03	neutral	4,59	neutral	-1,76	neutral	-1,51	low_impact	1,94	neutral	0,71	neutral	0,56	deleterious	2,62	20,3	0,05	0,35	neutral	0,37	disease	0,67	disease	0,65	disease	0,72	4	neutral	0,97	deleterious	0,49	neutral	-2	neutral	0,21	medium_impact	0,41	medium_impact	-0,64	medium_impact	0,79	0,46	0,8	31,15	23,21	N	0,4	N	0,64	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11655	11655	C	T	MI.18205	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	896	299	T	M	aCa/aTa	0,72	0	0	benign	0,01	neutral	0,23	neutral	4,82	neutral	1,78	neutral	-0,11	neutral_impact	-0,34	neutral	0,78	neutral	0,96	neutral	1,07	11,07	0,09	0,4	disease	0,65	neutral	0,42	neutral	0,32	disease	0,61	2	neutral	0,77	deleterious	0,61	neutral	-6	neutral	0,35	medium_impact	1,16	medium_impact	-0,09	low_impact	-1,46	0,48	0,8	31,15	23,21	N	0,37	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11657	11657	G	A	MI.18206	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	898	300	A	T	Gcc/Acc	-2,5	0	0	probably_damaging	0,95	neutral	0,05	neutral	4,54	deleterious	-3,23	deleterious	-3,42	medium_impact	2,22	neutral	0,75	neutral	0,52	deleterious	4,31	24	0,09	0,35	neutral	0,32	disease	0,76	disease	0,54	disease	0,55	1	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,75	low_impact	-1,92	medium_impact	-0,52	medium_impact	1,07	0,75	0,85	34,86	8,76	N	0,42	N	0,84	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11657	11657	G	C	MI.18207	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	898	300	A	P	Gcc/Ccc	-2,5	0	0	probably_damaging	0,99	deleterious	0	neutral	4,48	deleterious	-4,47	deleterious	-4,25	high_impact	3,92	neutral	0,69	damaging	0,25	deleterious	3,93	23,5	0,02	0,35	disease	0,76	disease	0,92	disease	0,74	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-2,59	low_impact	-1,48	high_impact	2,75	0,61	0,8	34,86	8,76	N	0,37	N	0,97	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11657	11657	G	T	MI.18208	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	898	300	A	S	Gcc/Tcc	-2,5	0	0	possibly_damaging	0,86	neutral	0,13	neutral	4,57	deleterious	-3,12	neutral	-2,33	low_impact	1,94	neutral	0,79	neutral	0,72	deleterious	3,73	23,3	0,16	0,45	neutral	0,46	disease	0,78	neutral	0,4	neutral	0,39	2	neutral	0,94	neutral	0,14	neutral	-3	deleterious	0,78	low_impact	-1,46	medium_impact	-0,26	medium_impact	0,79	0,58	0,8	34,86	8,76	N	0,41	N	0,31	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11658	11658	C	A	MI.18209	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	899	300	A	D	gCc/gAc	5,09	1	0	probably_damaging	0,98	deleterious	0	neutral	4,48	deleterious	-5,18	deleterious	-4,87	high_impact	3,92	neutral	0,72	neutral	0,32	deleterious	4,7	24,6	0,02	0,35	disease	0,52	disease	0,92	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,31	low_impact	-1,48	high_impact	2,75	0,36	0,8	34,86	8,76	P	0,58	P	1	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8543	8543	T	A	MI.1821	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	178	60	S	T	Tcg/Acg	4,76	1	0	possibly_damaging	0,85	neutral	0,58	neutral	1,79	neutral	-1,59	neutral	-1,26	medium_impact	2,29	neutral	1	neutral	0,5	deleterious	4,13	23,8	0,42653776	0,85	neutral	0,38	neutral	0,22	disease	0,53	neutral	0,2	6	neutral	0,82	neutral	0,37	NA	0	deleterious	0,59	low_impact	-1,47	medium_impact	0,37	medium_impact	0,87	0,62	0,85	NA	NA	P	0,58	P	0,26	polymorphism	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11658	11658	C	G	MI.18210	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	899	300	A	G	gCc/gGc	5,09	1	0	benign	0,15	neutral	1	neutral	4,66	neutral	0,52	neutral	-2,24	low_impact	0,91	neutral	0,63	neutral	0,62	deleterious	2,03	16,4	0,17	0,45	disease	0,63	neutral	0,2	neutral	0,34	neutral	0,48	0	neutral	0,15	deleterious	0,93	neutral	-6	deleterious	0,72	medium_impact	-0,01	high_impact	1,88	medium_impact	-0,23	0,62	0,8	34,86	8,76	P	0,5	N	0,6	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11658	11658	C	T	MI.18211	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	899	300	A	V	gCc/gTc	5,09	1	0	probably_damaging	0,96	deleterious	0	neutral	4,63	neutral	-2,66	deleterious	-3,61	medium_impact	3,23	neutral	0,76	neutral	0,44	deleterious	4,51	24,3	0,05	0,35	disease	0,72	disease	0,85	disease	0,6	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,83	low_impact	-2,01	low_impact	-1,48	high_impact	2,07	0,65	0,8	34,86	8,76	P	0,58	P	0,85	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11660	11660	A	G	MI.18212	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	901	301	I	V	Att/Gtt	-12,86	0	0	benign	0,01	neutral	0,13	neutral	4,45	neutral	-0,51	neutral	-0,48	low_impact	1,16	neutral	0,81	neutral	0,99	deleterious	0,03	2,92	0,54	0,6	disease	0,51	neutral	0,24	neutral	0,39	neutral	0,34	3	neutral	0,87	deleterious	0,56	neutral	-6	neutral	0,13	medium_impact	1,16	medium_impact	-0,26	medium_impact	0,02	0,51	0,8	26,58	22,22	N	0,39	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11660	11660	A	T	MI.18213	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	901	301	I	F	Att/Ttt	-12,86	0	0	possibly_damaging	0,55	neutral	0,06	neutral	4,39	neutral	-1,48	deleterious	-3,09	medium_impact	2,14	neutral	0,69	neutral	0,43	deleterious	3,73	23,3	0,14	0,4	disease	0,75	disease	0,7	disease	0,61	disease	0,69	4	neutral	0,94	neutral	0,26	NA	0	deleterious	0,61	medium_impact	-0,8	medium_impact	-0,47	medium_impact	0,99	0,66	0,8	26,58	22,22	N	0,34	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11660	11660	A	C	MI.18214	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	901	301	I	L	Att/Ctt	-12,86	0	0	benign	0,12	neutral	0,56	neutral	4,49	neutral	0,69	neutral	-1,41	neutral_impact	0,32	neutral	0,73	neutral	0,64	deleterious	1,95	15,93	0,28	0,45	disease	0,56	neutral	0,42	neutral	0,38	disease	0,6	2	neutral	0,35	deleterious	0,72	neutral	-6	neutral	0,18	medium_impact	0,1	medium_impact	0,26	medium_impact	-0,81	0,59	0,8	26,58	22,22	N	0,29	N	0,63	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11661	11661	T	A	MI.18215	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	902	301	I	N	aTt/aAt	0,26	0	0	benign	0,38	deleterious	0,01	neutral	4,32	deleterious	-4,65	deleterious	-5,03	high_impact	3,62	neutral	0,66	neutral	0,45	deleterious	4,31	24	0,05	0,35	disease	0,77	disease	0,74	disease	0,62	disease	0,69	4	deleterious	0,99	neutral	0,32	deleterious	2	deleterious	0,71	medium_impact	-0,52	medium_impact	-0,92	high_impact	2,46	0,35	0,8	26,58	22,22	N	0,33	N	0,87	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11661	11661	T	G	MI.18216	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	902	301	I	S	aTt/aGt	0,26	0	0	benign	0,01	neutral	0,07	neutral	4,39	deleterious	-3,32	deleterious	-3,79	low_impact	1,42	neutral	0,74	neutral	0,76	neutral	1,64	14,05	0,02	0,35	neutral	0,48	disease	0,64	neutral	0,44	neutral	0,35	3	neutral	0,93	deleterious	0,53	neutral	-6	deleterious	0,45	medium_impact	1,16	medium_impact	-0,43	medium_impact	0,28	0,33	0,8	26,58	22,22	N	0,44	N	0,36	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11661	11661	T	C	MI.18217	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	902	301	I	T	aTt/aCt	0,26	0	0	benign	0,18	neutral	0,12	neutral	4,39	neutral	-2,81	deleterious	-3	low_impact	1,28	neutral	0,7	neutral	0,74	deleterious	0,51	7,48	0,05	0,35	disease	0,71	neutral	0,34	neutral	0,4	disease	0,64	3	neutral	0,86	deleterious	0,47	neutral	-6	neutral	0,41	medium_impact	-0,1	medium_impact	-0,28	medium_impact	0,14	0,29	0,8	26,58	22,22	N	0,44	N	0,53	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11662	11662	T	A	MI.18218	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	903	301	I	M	atT/atA	0,95	0	0	possibly_damaging	0,73	neutral	0,17	neutral	4,39	neutral	-2,4	neutral	-2,07	low_impact	1,66	neutral	0,7	neutral	0,48	deleterious	3,55	23,1	0,22	0,45	disease	0,79	neutral	0,42	disease	0,61	disease	0,67	3	neutral	0,87	neutral	0,22	neutral	-3	deleterious	0,59	low_impact	-1,12	medium_impact	-0,18	medium_impact	0,52	0,61	0,8	26,58	22,22	N	0,37	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11662	11662	T	G	MI.18219	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	903	301	I	M	atT/atG	0,95	0	0	possibly_damaging	0,73	neutral	0,17	neutral	4,39	neutral	-2,4	neutral	-2,07	low_impact	1,66	neutral	0,7	neutral	0,48	deleterious	3,2	22,7	0,22	0,45	disease	0,79	neutral	0,42	disease	0,61	disease	0,67	3	neutral	0,87	neutral	0,22	neutral	-3	deleterious	0,59	low_impact	-1,12	medium_impact	-0,18	medium_impact	0,52	0,61	0,8	26,58	22,22	N	0,37	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8543	8543	T	C	MI.1822	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	178	60	S	P	Tcg/Ccg	4,76	1	0	probably_damaging	0,94	neutral	0,28	neutral	1,74	deleterious	-3,17	neutral	-2,12	medium_impact	2,64	neutral	1	damaging	0,28	deleterious	4,15	23,8	0,30302861	0,85	disease	0,61	neutral	0,48	disease	0,55	neutral	0,4	2	neutral	0,95	neutral	0,17	deleterious	1	deleterious	0,7	low_impact	-1,89	medium_impact	0,06	medium_impact	1,17	0,36	0,85	NA	NA	P	0,63	P	0,54	polymorphism	0,95	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11663	11663	C	G	MI.18220	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	904	302	L	V	Ctc/Gtc	-9,18	0	0	possibly_damaging	0,86	neutral	0,11	neutral	4,37	neutral	-0,31	neutral	-2,38	medium_impact	2,02	neutral	0,73	neutral	0,57	deleterious	3,51	23,1	0,32	0,5	disease	0,66	disease	0,6	disease	0,55	disease	0,51	0	neutral	0,95	neutral	0,13	NA	0	deleterious	0,76	low_impact	-1,46	medium_impact	-0,31	medium_impact	0,87	0,55	0,8	18,3	20,92	N	0,35	N	0,38	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11663	11663	C	T	MI.18221	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	904	302	L	F	Ctc/Ttc	-9,18	0	0	benign	0,29	neutral	0,41	neutral	4,31	neutral	-0,22	deleterious	-3,29	low_impact	1,27	neutral	0,74	neutral	0,64	deleterious	4,06	23,7	0,27	0,45	disease	0,81	disease	0,62	neutral	0,43	neutral	0,48	0	neutral	0,51	deleterious	0,56	neutral	-6	deleterious	0,8	medium_impact	-0,35	medium_impact	0,11	medium_impact	0,13	0,48	0,8	18,3	20,92	N	0,23	N	0,56	polymorphism	1	0,07	rs28588274	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11663	11663	C	A	MI.18222	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	904	302	L	I	Ctc/Atc	-9,18	0	0	possibly_damaging	0,86	neutral	0,16	neutral	4,4	neutral	-0,55	neutral	-1,66	low_impact	1,8	neutral	0,73	neutral	0,71	deleterious	4,15	23,8	0,36	0,5	disease	0,7	disease	0,63	neutral	0,41	neutral	0,39	2	neutral	0,93	neutral	0,15	neutral	-3	deleterious	0,77	low_impact	-1,46	medium_impact	-0,2	medium_impact	0,66	0,53	0,8	18,3	20,92	N	0,38	N	0,46	polymorphism	1	0,03	rs28588274	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11664	11664	T	A	MI.18223	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	905	302	L	H	cTc/cAc	-1,35	0	0	probably_damaging	0,99	deleterious	0,01	neutral	4,22	deleterious	-3,74	deleterious	-5,93	high_impact	3,79	neutral	0,69	neutral	0,44	deleterious	4,11	23,7	0,03	0,35	disease	0,9	disease	0,81	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,59	medium_impact	-0,92	high_impact	2,62	0,17	0,8	18,3	20,92	N	0,34	N	0,89	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11664	11664	T	G	MI.18224	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	905	302	L	R	cTc/cGc	-1,35	0	0	probably_damaging	0,99	deleterious	0,01	neutral	4,23	deleterious	-3,28	deleterious	-5	high_impact	3,79	neutral	0,68	neutral	0,39	deleterious	4,23	23,9	0,02	0,35	disease	0,85	disease	0,89	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,59	medium_impact	-0,92	high_impact	2,62	0,14	0,8	18,3	20,92	N	0,34	N	0,95	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11664	11664	T	C	MI.18225	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	905	302	L	P	cTc/cCc	-1,35	0	0	probably_damaging	0,99	deleterious	0,01	neutral	4,22	deleterious	-3,71	deleterious	-5,95	high_impact	3,79	neutral	0,65	neutral	0,38	deleterious	3,98	23,6	0,01	0,35	disease	0,9	disease	0,86	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-2,59	medium_impact	-0,92	high_impact	2,62	0,18	0,8	18,3	20,92	N	0,35	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11666	11666	A	C	MI.18226	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	907	303	I	L	Atc/Ctc	-5,96	0	0	probably_damaging	1	neutral	0,29	neutral	4,65	neutral	0,46	neutral	-1,6	low_impact	1,25	neutral	0,79	neutral	0,72	deleterious	3,86	23,5	0,23	0,45	neutral	0,35	disease	0,62	neutral	0,45	neutral	0,34	3	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,63	low_impact	-3,54	medium_impact	-0,02	medium_impact	0,11	0,35	0,8	18,3	19,83	N	0,37	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11666	11666	A	G	MI.18227	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	907	303	I	V	Atc/Gtc	-5,96	0	0	probably_damaging	1	neutral	0,29	neutral	4,68	neutral	0,37	neutral	-0,79	low_impact	1,92	neutral	0,74	neutral	0,42	deleterious	3,1	22,5	0,44	0,55	disease	0,59	neutral	0,41	neutral	0,48	disease	0,59	2	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,65	low_impact	-3,54	medium_impact	-0,02	medium_impact	0,77	0,29	0,8	18,3	19,83	N	0,39	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11666	11666	A	T	MI.18228	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	907	303	I	F	Atc/Ttc	-5,96	0	0	probably_damaging	1	neutral	0,15	neutral	4,63	neutral	-1,92	deleterious	-3,49	medium_impact	3,27	neutral	0,66	damaging	0,13	deleterious	3,87	23,5	0,2	0,45	disease	0,58	disease	0,82	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,22	high_impact	2,11	0,44	0,8	18,3	19,83	N	0,32	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11667	11667	T	G	MI.18229	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	908	303	I	S	aTc/aGc	5,55	0,99	0	probably_damaging	1	neutral	0,63	neutral	4,85	neutral	-0,92	deleterious	-5,13	neutral_impact	0,61	neutral	0,74	damaging	0,24	deleterious	4,36	24,1	0,05	0,35	disease	0,69	disease	0,78	neutral	0,5	neutral	0,41	2	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,78	low_impact	-3,54	medium_impact	0,33	medium_impact	-0,52	0,13	0,8	18,3	19,83	N	0,45	N	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8543	8543	T	G	MI.1823	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	178	60	S	A	Tcg/Gcg	4,76	1	0	possibly_damaging	0,78	neutral	0,76	neutral	1,81	neutral	-1,08	neutral	-1,26	medium_impact	2,64	neutral	1	neutral	0,59	deleterious	4,06	23,7	0,5519299	0,85	neutral	0,27	neutral	0,18	disease	0,56	neutral	0,2	6	neutral	0,73	deleterious	0,49	NA	0	deleterious	0,52	low_impact	-1,28	medium_impact	0,57	medium_impact	1,17	0,46	0,85	NA	NA	P	0,55	P	0,26	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11667	11667	T	A	MI.18230	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	908	303	I	N	aTc/aAc	5,55	0,99	0	probably_damaging	1	neutral	0,1	neutral	4,66	deleterious	-4,02	deleterious	-6,08	medium_impact	2,37	neutral	0,65	damaging	0,13	deleterious	4,54	24,3	0,09	0,35	disease	0,79	disease	0,84	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,33	medium_impact	1,22	0,15	0,8	18,3	19,83	P	0,53	P	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11667	11667	T	C	MI.18231	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	908	303	I	T	aTc/aCc	5,55	0,99	0	probably_damaging	1	neutral	0,73	neutral	4,68	neutral	-1,27	deleterious	-4,13	neutral_impact	0,32	neutral	0,73	neutral	0,35	deleterious	2,35	18,48	0,12	0,4	disease	0,56	neutral	0,38	neutral	0,47	disease	0,58	2	deleterious	1	neutral	0,37	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	0,44	medium_impact	-0,81	0,24	0,8	18,3	19,83	N	0,51	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11668	11668	C	A	MI.18232	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	909	303	I	M	atC/atA	2,33	0,98	0	probably_damaging	1	neutral	0,09	neutral	4,63	neutral	-1,45	neutral	-2,26	medium_impact	2,06	neutral	0,81	neutral	0,42	deleterious	2,82	21,5	0,28	0,45	neutral	0,47	disease	0,56	disease	0,57	neutral	0,46	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,69	low_impact	-3,54	medium_impact	-0,36	medium_impact	0,91	0,42	0,8	18,3	19,83	P	0,52	P	0,43	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11668	11668	C	G	MI.18233	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	909	303	I	M	atC/atG	2,33	0,98	0	probably_damaging	1	neutral	0,09	neutral	4,63	neutral	-1,45	neutral	-2,26	medium_impact	2,06	neutral	0,81	neutral	0,42	deleterious	2,37	18,63	0,28	0,45	neutral	0,47	disease	0,56	disease	0,57	neutral	0,46	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,69	low_impact	-3,54	medium_impact	-0,36	medium_impact	0,91	0,42	0,8	18,3	19,83	N	0,51	P	0,43	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11669	11669	C	G	MI.18234	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	910	304	Q	E	Caa/Gaa	-5,04	0	0	possibly_damaging	0,64	neutral	0,4	neutral	4,61	neutral	-1,18	deleterious	-2,75	medium_impact	3	neutral	0,7	neutral	0,42	deleterious	3,21	22,7	0,37	0,5	disease	0,72	disease	0,82	disease	0,74	disease	0,71	4	neutral	0,67	neutral	0,38	NA	0	deleterious	0,82	medium_impact	-0,95	medium_impact	0,1	medium_impact	1,84	0,41	0,8	45,75	9,12	N	0,31	N	0,93	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11669	11669	C	A	MI.18235	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	910	304	Q	K	Caa/Aaa	-5,04	0	0	benign	0,08	neutral	0,41	neutral	4,62	neutral	-0,94	deleterious	-3,7	medium_impact	2,46	neutral	0,74	neutral	0,44	deleterious	4,04	23,7	0,24	0,45	neutral	0,34	disease	0,86	disease	0,55	disease	0,55	1	neutral	0,54	deleterious	0,67	neutral	-3	deleterious	0,75	medium_impact	0,28	medium_impact	0,11	medium_impact	1,31	0,33	0,8	45,75	9,12	N	0,33	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11670	11670	A	C	MI.18236	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	911	304	Q	P	cAa/cCa	5,32	1	0	probably_damaging	0,96	neutral	0,24	neutral	4,61	neutral	-1,75	deleterious	-5,57	medium_impact	3,26	neutral	0,73	neutral	0,44	deleterious	3,46	23	0,03	0,35	disease	0,92	disease	0,91	disease	0,78	disease	0,74	5	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,91	low_impact	-2,01	medium_impact	-0,08	high_impact	2,1	0,18	0,8	45,75	9,12	P	0,65	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11670	11670	A	G	MI.18237	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	911	304	Q	R	cAa/cGa	5,32	1	0	possibly_damaging	0,74	neutral	0,42	neutral	4,62	neutral	-1,08	deleterious	-3,67	medium_impact	2,66	neutral	0,69	neutral	0,48	deleterious	3,52	23,1	0,22	0,45	disease	0,79	disease	0,86	disease	0,59	disease	0,63	3	neutral	0,75	neutral	0,34	NA	0	deleterious	0,85	low_impact	-1,14	medium_impact	0,12	medium_impact	1,51	0,11	0,8	45,75	9,12	P	0,6	P	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11670	11670	A	T	MI.18238	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	911	304	Q	L	cAa/cTa	5,32	1	0	possibly_damaging	0,88	neutral	0,74	neutral	4,89	neutral	2,62	deleterious	-6,52	low_impact	1,44	neutral	0,73	neutral	0,44	deleterious	3,94	23,5	0,07	0,35	disease	0,68	disease	0,84	disease	0,57	neutral	0,48	0	neutral	0,85	neutral	0,43	neutral	-3	deleterious	0,82	low_impact	-1,53	medium_impact	0,46	medium_impact	0,3	0,12	0,8	45,75	9,12	N	0,44	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11671	11671	A	C	MI.18239	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	912	304	Q	H	caA/caC	5,55	1	0	probably_damaging	0,98	neutral	0,57	neutral	4,61	neutral	-1,68	deleterious	-4,32	medium_impact	2,91	neutral	0,78	neutral	0,47	deleterious	3,42	23	0,24	0,45	disease	0,9	disease	0,8	disease	0,66	disease	0,69	4	neutral	0,97	neutral	0,3	deleterious	1	deleterious	0,86	low_impact	-2,31	medium_impact	0,27	medium_impact	1,75	0,4	0,8	45,75	9,12	P	0,53	P	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8544	8544	C	G	MI.1824	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	179	60	S	W	tCg/tGg	5,91	1	0	probably_damaging	0,98	deleterious	0,02	neutral	1,73	deleterious	-4,7	deleterious	-3,34	medium_impact	2,64	neutral	1	neutral	0,37	deleterious	4,3	24	0,21080113	0,85	disease	0,83	neutral	0,43	disease	0,63	neutral	0,29	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,77	low_impact	-2,36	medium_impact	-0,66	medium_impact	1,17	0,17	0,85	NA	NA	P	0,64	P	0,53	disease_causing	0,99	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11671	11671	A	T	MI.18240	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	912	304	Q	H	caA/caT	5,55	1	0	probably_damaging	0,98	neutral	0,57	neutral	4,61	neutral	-1,68	deleterious	-4,32	medium_impact	2,91	neutral	0,78	neutral	0,47	deleterious	3,65	23,2	0,24	0,45	disease	0,9	disease	0,8	disease	0,66	disease	0,69	4	neutral	0,97	neutral	0,3	deleterious	1	deleterious	0,86	low_impact	-2,31	medium_impact	0,27	medium_impact	1,75	0,4	0,8	45,75	9,12	P	0,53	P	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11672	11672	A	T	MI.18241	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	913	305	T	S	Acc/Tcc	3,25	1	0	probably_damaging	1	neutral	0,48	neutral	4,6	neutral	-1,19	deleterious	-3,37	low_impact	1,72	neutral	0,79	neutral	0,85	deleterious	2,17	17,33	0,35	0,5	disease	0,65	disease	0,58	neutral	0,37	neutral	0,36	3	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,75	low_impact	-3,54	medium_impact	0,18	medium_impact	0,58	0,57	0,8	15,69	16,36	N	0,46	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11672	11672	A	G	MI.18242	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	913	305	T	A	Acc/Gcc	3,25	1	0	probably_damaging	1	deleterious	0,03	neutral	4,55	neutral	-1,92	deleterious	-4,44	medium_impact	3,38	neutral	0,69	damaging	0,15	deleterious	3,48	23,1	0,2	0,45	disease	0,55	disease	0,7	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,71	low_impact	-3,54	medium_impact	-0,64	high_impact	2,22	0,26	0,8	15,69	16,36	P	0,52	P	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11672	11672	A	C	MI.18243	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	913	305	T	P	Acc/Ccc	3,25	1	0	probably_damaging	1	deleterious	0,01	neutral	4,49	deleterious	-4,23	deleterious	-5,42	high_impact	3,84	neutral	0,68	damaging	0,14	deleterious	3,51	23,1	0,04	0,35	disease	0,88	disease	0,88	disease	0,55	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,54	medium_impact	-0,92	high_impact	2,67	0,32	0,8	15,69	16,36	P	0,5	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11673	11673	C	A	MI.18244	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	914	305	T	N	aCc/aAc	3,71	1	0	probably_damaging	1	neutral	0,27	neutral	4,66	neutral	-1,67	deleterious	-4,44	low_impact	1,73	neutral	0,69	damaging	0,17	deleterious	3,91	23,5	0,29	0,45	disease	0,85	disease	0,75	disease	0,57	disease	0,59	2	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,78	low_impact	-3,54	medium_impact	-0,04	medium_impact	0,59	0,47	0,8	15,69	16,36	N	0,51	P	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11673	11673	C	G	MI.18245	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	914	305	T	S	aCc/aGc	3,71	1	0	probably_damaging	1	neutral	0,48	neutral	4,6	neutral	-1,19	deleterious	-3,37	low_impact	1,72	neutral	0,79	neutral	0,85	deleterious	2,52	19,57	0,35	0,5	disease	0,65	disease	0,58	neutral	0,37	neutral	0,36	3	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,75	low_impact	-3,54	medium_impact	0,18	medium_impact	0,58	0,57	0,8	15,69	16,36	P	0,49	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11673	11673	C	T	MI.18246	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	914	305	T	I	aCc/aTc	3,71	1	0	probably_damaging	1	neutral	0,12	neutral	4,51	deleterious	-4,04	deleterious	-5,51	medium_impact	3,29	neutral	0,73	damaging	0,11	deleterious	4,03	23,6	0,09	0,35	neutral	0,35	disease	0,88	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	-0,28	high_impact	2,13	0,36	0,8	15,69	16,36	N	0,5	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11675	11675	C	A	MI.18247	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	916	306	P	T	Ccc/Acc	-7,57	0	0	probably_damaging	1	neutral	0,39	neutral	4,67	neutral	-1,53	deleterious	-6,75	medium_impact	2,06	neutral	0,79	neutral	0,59	deleterious	3,76	23,3	0,23	0,45	disease	0,53	disease	0,59	neutral	0,37	neutral	0,36	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,09	medium_impact	0,91	0,46	0,8	11,98	17,11	N	0,28	N	0,49	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11675	11675	C	G	MI.18248	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	916	306	P	A	Ccc/Gcc	-7,57	0	0	probably_damaging	1	neutral	0,49	neutral	4,76	neutral	-0,52	deleterious	-7,03	medium_impact	2,44	neutral	0,75	neutral	0,52	deleterious	3,21	22,7	0,21	0,45	neutral	0,35	disease	0,58	disease	0,56	disease	0,51	0	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,71	low_impact	-3,54	medium_impact	0,19	medium_impact	1,29	0,64	0,8	11,98	17,11	N	0,3	N	0,59	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11675	11675	C	T	MI.18249	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	916	306	P	S	Ccc/Tcc	-7,57	0	0	probably_damaging	1	neutral	0,41	neutral	4,77	neutral	-0,98	deleterious	-6,95	low_impact	1,31	neutral	0,76	neutral	0,55	deleterious	4	23,6	0,28	0,45	neutral	0,42	disease	0,68	neutral	0,37	neutral	0,36	3	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,73	low_impact	-3,54	medium_impact	0,11	medium_impact	0,17	0,14	0,8	11,98	17,11	N	0,28	N	0,54	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8544	8544	C	T	MI.1825	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	179	60	S	L	tCg/tTg	5,91	1	0	possibly_damaging	0,9	neutral	0,34	neutral	2,09	neutral	1,02	neutral	-0,88	neutral_impact	-0,36	neutral	0,99	neutral	0,96	deleterious	1,92	15,69	0,39005501	0,85	neutral	0,13	neutral	0,12	neutral	0,23	neutral	0,07	9	neutral	0,91	neutral	0,22	neutral	-3	deleterious	0,6	low_impact	-1,66	medium_impact	0,13	low_impact	-1,41	0,61	0,85	NA	NA	P	0,61	P	0,13	polymorphism	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11676	11676	C	A	MI.18250	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	917	306	P	H	cCc/cAc	2,1	0,84	0	probably_damaging	1	neutral	0,54	neutral	4,63	neutral	-2,76	deleterious	-8,02	medium_impact	2,42	neutral	0,72	neutral	0,54	deleterious	4,17	23,8	0,09	0,35	disease	0,8	disease	0,76	disease	0,68	disease	0,6	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,24	medium_impact	1,27	0,24	0,8	11,98	17,11	N	0,33	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11676	11676	C	G	MI.18251	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	917	306	P	R	cCc/cGc	2,1	0,84	0	probably_damaging	1	neutral	0,34	neutral	4,66	neutral	-1,85	deleterious	-7,97	medium_impact	3	neutral	0,74	neutral	0,37	deleterious	3,75	23,3	0,08	0,35	disease	0,75	disease	0,87	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,82	low_impact	-3,54	medium_impact	0,04	medium_impact	1,84	0,26	0,8	11,98	17,11	N	0,43	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11676	11676	C	T	MI.18252	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	917	306	P	L	cCc/cTc	2,1	0,84	0	probably_damaging	1	neutral	0,64	neutral	4,72	neutral	-2,22	deleterious	-8,87	medium_impact	2,05	neutral	0,71	neutral	0,4	deleterious	4,55	24,4	0,16	0,45	disease	0,57	disease	0,8	disease	0,64	disease	0,57	1	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,34	medium_impact	0,9	0,56	0,8	11,98	17,11	N	0,32	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11678	11678	T	C	MI.18253	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	919	307	W	R	Tga/Cga	-3,89	0	0	benign	0,17	deleterious	0,02	neutral	4,6	neutral	-1,13	deleterious	-10,97	high_impact	3,61	neutral	0,69	neutral	0,3	deleterious	3,67	23,2	0,04	0,35	disease	0,77	disease	0,93	disease	0,82	disease	0,8	6	neutral	0,98	neutral	0,43	deleterious	2	deleterious	0,87	medium_impact	-0,07	medium_impact	-0,75	high_impact	2,45	0,06	0,8	15,03	20,18	N	0,41	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11678	11678	T	G	MI.18254	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	919	307	W	G	Tga/Gga	-3,89	0	0	probably_damaging	0,91	deleterious	0,03	neutral	4,59	neutral	-1,59	deleterious	-10,52	high_impact	3,61	neutral	0,68	neutral	0,45	deleterious	4,03	23,7	0,05	0,35	disease	0,67	disease	0,89	disease	0,79	disease	0,74	5	deleterious	0,99	neutral	0,06	deleterious	6	deleterious	0,79	low_impact	-1,66	medium_impact	-0,64	high_impact	2,45	0,04	0,8	15,03	20,18	N	0,46	N	0,91	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11679	11679	G	C	MI.18255	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	920	307	W	S	tGa/tCa	3,71	1	0	probably_damaging	0,94	neutral	0,11	neutral	4,68	neutral	0,59	deleterious	-10,97	medium_impact	2,13	neutral	0,73	neutral	0,49	deleterious	4,14	23,8	0,08	0,35	neutral	0,48	disease	0,91	disease	0,67	neutral	0,46	1	neutral	0,98	neutral	0,09	deleterious	1	deleterious	0,81	low_impact	-1,84	medium_impact	-0,31	medium_impact	0,98	0,09	0,8	15,03	20,18	P	0,51	P	0,94	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11679	11679	G	T	MI.18256	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	920	307	W	L	tGa/tTa	3,71	1	0	possibly_damaging	0,88	neutral	0,17	neutral	4,67	neutral	0,49	deleterious	-9,27	low_impact	1,42	neutral	0,76	neutral	0,71	deleterious	3,22	22,7	0,09	0,35	disease	0,69	disease	0,82	disease	0,63	neutral	0,45	1	neutral	0,93	neutral	0,15	neutral	-3	deleterious	0,75	low_impact	-1,53	medium_impact	-0,18	medium_impact	0,28	0,04	0,8	15,03	20,18	P	0,53	P	0,54	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11680	11680	A	C	MI.18257	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	921	307	W	C	tgA/tgC	3,48	1	0	probably_damaging	0,98	deleterious	0,02	neutral	4,58	neutral	-2,5	deleterious	-10,05	medium_impact	3,47	neutral	0,69	neutral	0,32	deleterious	4,14	23,8	0,05	0,35	disease	0,81	disease	0,92	disease	0,8	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,84	low_impact	-2,31	medium_impact	-0,75	high_impact	2,31	0,08	0,8	15,03	20,18	P	0,56	P	0,86	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11680	11680	A	T	MI.18258	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	921	307	W	C	tgA/tgT	3,48	1	0	probably_damaging	0,98	deleterious	0,02	neutral	4,58	neutral	-2,5	deleterious	-10,05	medium_impact	3,47	neutral	0,69	neutral	0,32	deleterious	4,25	23,9	0,05	0,35	disease	0,81	disease	0,92	disease	0,8	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,84	low_impact	-2,31	medium_impact	-0,75	high_impact	2,31	0,08	0,8	15,03	20,18	P	0,57	P	0,86	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11681	11681	A	T	MI.18259	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	922	308	S	C	Agc/Tgc	2,1	1	0	probably_damaging	1	deleterious	0	neutral	4,42	deleterious	-4,46	deleterious	-4,29	high_impact	3,86	neutral	0,65	damaging	0,05	deleterious	3,62	23,2	0,05	0,35	disease	0,9	disease	0,86	disease	0,54	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,69	0,41	0,8	44,66	8,21	N	0,46	N	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8546	8546	C	T	MI.1826	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	181	61	L	F	Ctt/Ttt	-0,33	0	0	probably_damaging	0,96	neutral	0,14	neutral	1,82	neutral	-2,67	neutral	-1,16	low_impact	1,36	neutral	1	neutral	0,64	deleterious	2,72	20,9	0,45432647	0,85	neutral	0,5	neutral	0,09	neutral	0,44	neutral	0,17	7	deleterious	0,98	neutral	0,09	neutral	-2	deleterious	0,66	low_impact	-2,07	medium_impact	-0,15	medium_impact	0,07	0,49	0,85	NA	NA	P	0,61	P	0,51	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11681	11681	A	C	MI.18260	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	922	308	S	R	Agc/Cgc	2,1	1	0	probably_damaging	1	deleterious	0,02	neutral	4,47	neutral	-2,05	deleterious	-4,05	high_impact	3,86	neutral	0,63	damaging	0,06	deleterious	4	23,6	0,04	0,35	disease	0,88	disease	0,93	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-3,54	medium_impact	-0,75	high_impact	2,69	0,49	0,8	44,66	8,21	N	0,51	P	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11681	11681	A	G	MI.18261	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	922	308	S	G	Agc/Ggc	2,1	1	0	probably_damaging	1	neutral	1	neutral	4,71	neutral	1,5	neutral	-1,39	neutral_impact	0,14	neutral	0,74	neutral	0,51	neutral	1,49	13,24	0,17	0,45	disease	0,82	neutral	0,15	neutral	0,31	neutral	0,36	3	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,71	low_impact	-3,54	high_impact	1,88	medium_impact	-0,99	0,5	0,8	44,66	8,21	N	0,41	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11682	11682	G	A	MI.18262	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	923	308	S	N	aGc/aAc	1,64	1	0	probably_damaging	1	deleterious	0	neutral	4,58	neutral	-1,94	neutral	-2,14	high_impact	3,86	neutral	0,67	damaging	0,08	deleterious	3,69	23,3	0,44	0,55	disease	0,8	disease	0,8	disease	0,6	disease	0,71	4	deleterious	1	deleterious	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,69	0,41	0,8	44,66	8,21	N	0,47	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11682	11682	G	C	MI.18263	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	923	308	S	T	aGc/aCc	1,64	1	0	probably_damaging	1	deleterious	0,02	neutral	4,47	neutral	-1,58	deleterious	-2,62	medium_impact	2,89	neutral	0,71	damaging	0,1	deleterious	3,44	23	0,23	0,45	neutral	0,44	disease	0,67	neutral	0,4	neutral	0,46	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,74	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,73	0,66	0,8	44,66	8,21	N	0,46	N	0,73	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11682	11682	G	T	MI.18264	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	923	308	S	I	aGc/aTc	1,64	1	0	probably_damaging	1	deleterious	0	neutral	4,43	neutral	-2,48	deleterious	-5,24	high_impact	3,52	neutral	0,69	damaging	0,08	deleterious	4,18	23,8	0,04	0,35	neutral	0,45	disease	0,92	disease	0,62	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	2,36	0,31	0,8	44,66	8,21	N	0,44	N	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11684	11684	T	A	MI.18265	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	925	309	F	I	Ttc/Atc	-6,88	0	0	possibly_damaging	0,63	neutral	0,26	neutral	4,83	neutral	0,6	deleterious	-4,14	neutral_impact	0,45	neutral	0,74	neutral	0,77	deleterious	4,51	24,3	0,15	0,4	neutral	0,43	disease	0,73	neutral	0,31	neutral	0,38	2	neutral	0,76	neutral	0,32	neutral	-3	deleterious	0,71	medium_impact	-0,94	medium_impact	-0,05	medium_impact	-0,68	0,62	0,8	22	22,88	N	0,39	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11684	11684	T	C	MI.18266	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	925	309	F	L	Ttc/Ctc	-6,88	0	0	benign	0,08	neutral	0,81	neutral	4,8	neutral	1,09	deleterious	-3,96	neutral_impact	-0,38	neutral	0,7	neutral	0,79	deleterious	2,93	22	0,22	0,45	neutral	0,44	neutral	0,47	neutral	0,33	neutral	0,46	1	neutral	0,09	deleterious	0,87	neutral	-6	deleterious	0,67	medium_impact	0,28	medium_impact	0,56	low_impact	-1,5	0,75	0,85	22	22,88	N	0,25	N	0,82	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11684	11684	T	G	MI.18267	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	925	309	F	V	Ttc/Gtc	-6,88	0	0	possibly_damaging	0,74	neutral	0,22	neutral	4,75	neutral	0,48	deleterious	-4,83	neutral_impact	0,71	neutral	0,76	neutral	0,62	deleterious	4,21	23,9	0,12	0,4	disease	0,53	disease	0,82	neutral	0,48	neutral	0,4	2	neutral	0,84	neutral	0,24	neutral	-3	deleterious	0,73	low_impact	-1,14	medium_impact	-0,11	medium_impact	-0,42	0,39	0,8	22	22,88	N	0,31	N	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11685	11685	T	C	MI.18268	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	926	309	F	S	tTc/tCc	1,64	0,01	0	probably_damaging	0,96	neutral	0,13	neutral	4,69	neutral	-1,61	deleterious	-6,05	low_impact	1,67	neutral	0,74	neutral	0,59	deleterious	4,29	24	0,05	0,35	neutral	0,41	disease	0,81	disease	0,52	disease	0,64	3	neutral	0,98	neutral	0,09	neutral	-2	deleterious	0,74	low_impact	-2,01	medium_impact	-0,26	medium_impact	0,53	0,25	0,8	22	22,88	N	0,39	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11685	11685	T	G	MI.18269	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	926	309	F	C	tTc/tGc	1,64	0,01	0	probably_damaging	0,98	neutral	0,11	neutral	4,59	deleterious	-3,43	deleterious	-5,97	medium_impact	2,27	neutral	0,74	neutral	0,69	deleterious	4,2	23,9	0,05	0,35	disease	0,75	disease	0,85	disease	0,53	disease	0,6	2	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,77	low_impact	-2,31	medium_impact	-0,31	medium_impact	1,12	0,26	0,8	22	22,88	N	0,36	N	0,95	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8546	8546	C	A	MI.1827	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	181	61	L	I	Ctt/Att	-0,33	0	0	possibly_damaging	0,9	neutral	0,19	neutral	1,86	neutral	-1,63	neutral	-0,33	low_impact	1,36	neutral	1	neutral	0,53	deleterious	2,46	19,23	0,45432647	0,85	neutral	0,33	neutral	0,07	neutral	0,41	neutral	0,16	7	neutral	0,94	neutral	0,15	neutral	-3	deleterious	0,62	low_impact	-1,66	medium_impact	-0,06	medium_impact	0,07	0,6	0,85	NA	NA	P	0,61	P	0,48	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11685	11685	T	A	MI.18270	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	926	309	F	Y	tTc/tAc	1,64	0,01	0	possibly_damaging	0,89	neutral	0,53	neutral	4,63	neutral	0,56	neutral	-1,18	neutral_impact	0,63	neutral	0,75	neutral	0,99	deleterious	3,1	22,5	0,18	0,45	disease	0,58	disease	0,6	neutral	0,34	neutral	0,38	2	neutral	0,87	neutral	0,32	neutral	-3	deleterious	0,72	low_impact	-1,57	medium_impact	0,23	medium_impact	-0,5	0,69	0,85	22	22,88	N	0,41	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11686	11686	C	A	MI.18271	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	927	309	F	L	ttC/ttA	0,49	0	0	benign	0,08	neutral	0,81	neutral	4,8	neutral	1,09	deleterious	-3,96	neutral_impact	-0,38	neutral	0,7	neutral	0,79	deleterious	3,45	23	0,22	0,45	neutral	0,44	neutral	0,47	neutral	0,33	neutral	0,46	1	neutral	0,09	deleterious	0,87	neutral	-6	deleterious	0,67	medium_impact	0,28	medium_impact	0,56	low_impact	-1,5	0,75	0,85	22	22,88	N	0,26	N	0,82	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11686	11686	C	G	MI.18272	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	927	309	F	L	ttC/ttG	0,49	0	0	benign	0,08	neutral	0,81	neutral	4,8	neutral	1,09	deleterious	-3,96	neutral_impact	-0,38	neutral	0,7	neutral	0,79	deleterious	3,14	22,6	0,22	0,45	neutral	0,44	neutral	0,47	neutral	0,33	neutral	0,46	1	neutral	0,09	deleterious	0,87	neutral	-6	deleterious	0,67	medium_impact	0,28	medium_impact	0,56	low_impact	-1,5	0,75	0,85	22	22,88	N	0,26	N	0,82	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11687	11687	A	C	MI.18273	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	928	310	T	P	Acc/Ccc	-4,12	0	0	possibly_damaging	0,72	neutral	0,1	neutral	4,56	neutral	-2,23	neutral	-2,48	medium_impact	2,8	neutral	0,66	neutral	0,52	deleterious	3,25	22,8	0,05	0,35	disease	0,72	disease	0,9	disease	0,72	disease	0,73	5	neutral	0,92	neutral	0,19	NA	0	deleterious	0,73	low_impact	-1,1	medium_impact	-0,33	medium_impact	1,64	0,34	0,8	24,18	34,28	N	0,33	N	0,75	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11687	11687	A	G	MI.18274	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	928	310	T	A	Acc/Gcc	-4,12	0	0	benign	0,02	neutral	0,34	neutral	4,64	neutral	-0,08	neutral	-1,1	low_impact	1,24	neutral	0,75	neutral	0,88	deleterious	0,4	6,59	0,15	0,4	neutral	0,41	neutral	0,5	neutral	0,37	neutral	0,37	3	neutral	0,64	deleterious	0,66	neutral	-6	neutral	0,16	medium_impact	0,87	medium_impact	0,04	medium_impact	0,1	0,39	0,8	24,18	34,28	N	0,43	N	0,22	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11687	11687	A	T	MI.18275	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	928	310	T	S	Acc/Tcc	-4,12	0	0	benign	0,04	neutral	0,87	neutral	4,67	neutral	0,37	neutral	-0,84	neutral_impact	0,46	neutral	0,68	neutral	0,77	deleterious	0,09	3,54	0,23	0,45	disease	0,52	neutral	0,29	neutral	0,31	neutral	0,38	2	neutral	0,06	deleterious	0,92	neutral	-6	neutral	0,32	medium_impact	0,58	medium_impact	0,67	medium_impact	-0,67	0,67	0,85	24,18	34,28	N	0,27	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11688	11688	C	G	MI.18276	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	929	310	T	S	aCc/aGc	3,02	0,96	0	benign	0,04	neutral	0,87	neutral	4,67	neutral	0,37	neutral	-0,84	neutral_impact	0,46	neutral	0,68	neutral	0,77	deleterious	0,31	5,83	0,23	0,45	disease	0,52	neutral	0,29	neutral	0,31	neutral	0,38	2	neutral	0,06	deleterious	0,92	neutral	-6	neutral	0,32	medium_impact	0,58	medium_impact	0,67	medium_impact	-0,67	0,67	0,85	24,18	34,28	N	0,36	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11688	11688	C	A	MI.18277	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	929	310	T	N	aCc/aAc	3,02	0,96	0	possibly_damaging	0,57	neutral	0,64	neutral	4,63	neutral	-0,21	neutral	-2,12	low_impact	1,25	neutral	0,68	neutral	0,61	deleterious	3,4	23	0,23	0,45	disease	0,51	disease	0,73	neutral	0,37	neutral	0,4	2	neutral	0,5	deleterious	0,54	neutral	-3	deleterious	0,59	medium_impact	-0,83	medium_impact	0,34	medium_impact	0,11	0,59	0,8	24,18	34,28	N	0,37	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11688	11688	C	T	MI.18278	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	929	310	T	I	aCc/aTc	3,02	0,96	0	possibly_damaging	0,57	neutral	0,29	neutral	4,65	neutral	0,11	neutral	-1,04	low_impact	1,77	neutral	0,73	neutral	0,53	deleterious	2,37	18,62	0,1	0,4	disease	0,79	disease	0,84	disease	0,56	disease	0,66	3	neutral	0,71	neutral	0,36	neutral	-3	deleterious	0,58	medium_impact	-0,83	medium_impact	-0,02	medium_impact	0,63	0,63	0,8	24,18	34,28	N	0,44	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11690	11690	G	A	MI.18279	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	931	311	G	S	Ggc/Agc	-0,2	0,54	0	probably_damaging	1	neutral	0,13	neutral	4,59	neutral	-2,95	deleterious	-5,71	medium_impact	1,95	damaging	0,55	neutral	0,35	deleterious	4,24	23,9	0,05	0,35	neutral	0,39	disease	0,85	disease	0,63	disease	0,61	2	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,26	medium_impact	0,8	0,71	0,85	46,41	9,01	N	0,32	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8546	8546	C	G	MI.1828	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	181	61	L	V	Ctt/Gtt	-0,33	0	0	possibly_damaging	0,9	neutral	0,32	neutral	1,87	neutral	-1,37	neutral	0,25	low_impact	1,36	neutral	1	neutral	0,67	neutral	1,63	14	0,51274914	0,85	neutral	0,31	neutral	0,08	neutral	0,43	neutral	0,17	7	neutral	0,91	neutral	0,21	neutral	-3	deleterious	0,61	low_impact	-1,66	medium_impact	0,11	medium_impact	0,07	0,49	0,85	NA	NA	P	0,6	P	0,4	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11690	11690	G	T	MI.18280	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	931	311	G	C	Ggc/Tgc	-0,2	0,54	0	probably_damaging	1	deleterious	0,01	neutral	4,51	deleterious	-6,12	deleterious	-8,58	high_impact	3,78	damaging	0,59	damaging	0,22	deleterious	4,22	23,9	0,02	0,35	disease	0,91	disease	0,92	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,54	medium_impact	-0,92	high_impact	2,61	0,2	0,8	46,41	9,01	N	0,4	N	0,98	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11690	11690	G	C	MI.18281	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	931	311	G	R	Ggc/Cgc	-0,2	0,54	0	probably_damaging	1	deleterious	0	neutral	4,5	deleterious	-4,41	deleterious	-7,62	high_impact	4,47	neutral	0,6	damaging	0,22	deleterious	4,03	23,7	0,02	0,35	disease	0,68	disease	0,93	disease	0,81	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,3	0,4	0,8	46,41	9,01	P	0,56	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11691	11691	G	C	MI.18282	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	932	311	G	A	gGc/gCc	6,01	1	0	probably_damaging	1	neutral	0,09	neutral	4,71	neutral	-0,42	deleterious	-5,71	medium_impact	2,64	damaging	0,58	neutral	0,43	deleterious	3,22	22,7	0,1	0,4	disease	0,57	disease	0,76	disease	0,6	disease	0,57	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,36	medium_impact	1,49	0,4	0,8	46,41	9,01	P	0,59	P	0,76	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11691	11691	G	A	MI.18283	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	932	311	G	D	gGc/gAc	6,01	1	0	probably_damaging	1	deleterious	0	neutral	4,49	deleterious	-4,89	deleterious	-6,66	high_impact	4,47	neutral	0,65	damaging	0,25	deleterious	3,89	23,5	0,02	0,35	disease	0,5	disease	0,91	disease	0,8	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,3	0,17	0,8	46,41	9,01	P	0,64	P	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11691	11691	G	T	MI.18284	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	932	311	G	V	gGc/gTc	6,01	1	0	probably_damaging	1	deleterious	0	neutral	4,61	neutral	-2,87	deleterious	-8,57	high_impact	3,78	damaging	0,58	damaging	0,28	deleterious	3,89	23,5	0,02	0,35	disease	0,66	disease	0,92	disease	0,71	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	2,61	0,24	0,8	46,41	9,01	P	0,61	P	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11693	11693	G	A	MI.18285	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	934	312	A	T	Gca/Aca	-9,87	0	0	probably_damaging	1	deleterious	0,02	neutral	4,26	deleterious	-4,01	deleterious	-3,78	medium_impact	2,38	neutral	0,68	damaging	0,14	deleterious	4,3	24	0,05	0,35	disease	0,65	disease	0,82	disease	0,58	disease	0,58	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,23	0,69	0,85	47,28	9,46	N	0,3	N	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11693	11693	G	C	MI.18286	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	934	312	A	P	Gca/Cca	-9,87	0	0	probably_damaging	1	deleterious	0	neutral	4,18	deleterious	-6,41	deleterious	-4,75	high_impact	4,32	neutral	0,65	damaging	0,12	deleterious	3,95	23,6	0,02	0,35	disease	0,84	disease	0,91	disease	0,76	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,15	0,49	0,8	47,28	9,46	N	0,41	N	0,96	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11693	11693	G	T	MI.18287	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	934	312	A	S	Gca/Tca	-9,87	0	0	probably_damaging	1	neutral	0,5	neutral	4,33	deleterious	-3,08	deleterious	-2,84	low_impact	1,74	neutral	0,68	damaging	0,22	deleterious	3,82	23,4	0,11	0,4	disease	0,57	disease	0,65	neutral	0,46	neutral	0,36	3	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,79	low_impact	-3,54	medium_impact	0,2	medium_impact	0,6	0,52	0,8	47,28	9,46	N	0,24	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11694	11694	C	G	MI.18288	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	935	312	A	G	gCa/gGa	5,09	1	0	probably_damaging	1	neutral	0,17	neutral	4,3	neutral	-2,34	deleterious	-3,8	medium_impact	2,35	neutral	0,73	damaging	0,18	deleterious	4,04	23,7	0,08	0,35	disease	0,62	disease	0,78	disease	0,64	disease	0,59	2	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,18	medium_impact	1,2	0,57	0,8	47,28	9,46	P	0,57	P	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11694	11694	C	T	MI.18289	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	935	312	A	V	gCa/gTa	5,09	1	0	probably_damaging	1	deleterious	0,01	neutral	4,25	deleterious	-3,1	deleterious	-3,79	medium_impact	3	neutral	0,7	damaging	0,13	deleterious	4,56	24,4	0,04	0,35	neutral	0,36	disease	0,88	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,84	0,68	0,85	47,28	9,46	P	0,53	P	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8547	8547	T	G	MI.1829	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	182	61	L	R	cTt/cGt	6,38	0,95	0	probably_damaging	0,98	neutral	0,49	neutral	1,83	neutral	-2,15	neutral	-0,18	low_impact	1,36	neutral	1	neutral	0,48	deleterious	3,07	22,4	0,36427644	0,85	disease	0,51	neutral	0,31	disease	0,54	neutral	0,18	6	deleterious	0,98	neutral	0,26	neutral	-2	deleterious	0,7	low_impact	-2,36	medium_impact	0,28	medium_impact	0,07	0,5	0,85	NA	NA	P	0,63	P	0,54	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11694	11694	C	A	MI.18290	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	935	312	A	E	gCa/gAa	5,09	1	0	probably_damaging	1	deleterious	0	neutral	4,21	deleterious	-5,64	deleterious	-4,74	high_impact	4,32	neutral	0,67	damaging	0,13	deleterious	4,57	24,4	0,02	0,35	disease	0,87	disease	0,92	disease	0,75	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,15	0,27	0,8	47,28	9,46	P	0,6	P	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11696	11696	G	A	MI.18291	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	937	313	V	I	Gtc/Atc	-11,25	0	0,03	benign	0,01	neutral	0,7	neutral	4,76	neutral	0,15	neutral	-0,32	neutral_impact	-0,58	damaging	0,28	neutral	0,34	neutral	-0,96	0,02	0,28	0,45	neutral	0,33	neutral	0,09	neutral	0,3	neutral	0,26	5	neutral	0,29	deleterious	0,85	neutral	-6	neutral	0,12	medium_impact	1,16	medium_impact	0,41	low_impact	-1,7	0,83	0,9	25,05	23,74	P	0,82	P	0,78	disease_causing_automatic	0	0,01	rs200873900	Pathogenic|Pathogenic	Leber_hereditary_optic_neuropathy_with_dystonia|Leber's_optic_atrophy	RCV000010356.2|RCV000055697.1	MedGen:OMIM|MedGen:OMIM:SNOMED_CT	.	.	.	.	G11696A	LHON/LDYT/DEAF/hypertension helper mut.	+	+	Reported-possibly synergistic	10
chrM	11696	11696	G	C	MI.18292	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	937	313	V	L	Gtc/Ctc	-11,25	0	0,03	benign	0,05	neutral	1	neutral	4,75	neutral	0,69	neutral	-0,54	neutral_impact	-0,44	neutral	0,7	neutral	0,91	neutral	-0,81	0,04	0,15	0,4	neutral	0,4	neutral	0,17	neutral	0,26	neutral	0,26	5	neutral	0,05	deleterious	0,98	neutral	-6	neutral	0,15	medium_impact	0,48	high_impact	1,88	low_impact	-1,56	0,53	0,8	25,05	23,74	N	0,33	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11696	11696	G	T	MI.18293	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	937	313	V	F	Gtc/Ttc	-11,25	0	0,03	benign	0,38	neutral	0,11	neutral	4,66	neutral	-1,98	neutral	-1,91	neutral_impact	0,13	neutral	0,73	neutral	0,59	neutral	0,96	10,43	0,04	0,35	neutral	0,4	disease	0,64	neutral	0,37	neutral	0,4	2	neutral	0,87	neutral	0,37	neutral	-6	neutral	0,29	medium_impact	-0,52	medium_impact	-0,31	medium_impact	-1	0,28	0,8	25,05	23,74	N	0,44	N	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11697	11697	T	A	MI.18294	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	938	313	V	D	gTc/gAc	0,95	0,01	0	possibly_damaging	0,47	deleterious	0,01	neutral	4,53	deleterious	-5,37	neutral	-2,32	medium_impact	2,18	neutral	0,75	neutral	0,51	deleterious	2,88	21,7	0,02	0,35	disease	0,88	disease	0,69	disease	0,66	disease	0,73	5	deleterious	0,99	neutral	0,27	deleterious	4	neutral	0,4	medium_impact	-0,67	medium_impact	-0,92	medium_impact	1,03	0,22	0,8	25,05	23,74	N	0,34	N	0,3	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11697	11697	T	C	MI.18295	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	938	313	V	A	gTc/gCc	0,95	0,01	0	benign	0,18	deleterious	0,02	neutral	4,61	neutral	-1,69	neutral	-0,95	low_impact	1,63	neutral	0,77	neutral	0,75	deleterious	0,57	7,96	0,07	0,35	neutral	0,34	neutral	0,28	disease	0,52	neutral	0,47	1	neutral	0,98	neutral	0,42	neutral	-2	neutral	0,17	medium_impact	-0,1	medium_impact	-0,75	medium_impact	0,49	0,17	0,8	25,05	23,74	N	0,47	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11697	11697	T	G	MI.18296	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	938	313	V	G	gTc/gGc	0,95	0,01	0	benign	0,26	deleterious	0,04	neutral	4,56	deleterious	-3,34	deleterious	-3,04	low_impact	1,83	neutral	0,75	neutral	0,55	deleterious	2,06	16,58	0,03	0,35	neutral	0,5	neutral	0,47	disease	0,55	disease	0,51	0	neutral	0,95	neutral	0,39	neutral	-2	neutral	0,27	medium_impact	-0,29	medium_impact	-0,57	medium_impact	0,68	0,3	0,8	25,05	23,74	N	0,42	N	0,42	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11699	11699	A	C	MI.18297	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	940	314	I	L	Att/Ctt	-6,42	0	0	benign	0,04	neutral	0,49	neutral	4,6	neutral	1,8	neutral	-0,54	neutral_impact	0,24	neutral	0,72	neutral	0,73	deleterious	0,85	9,79	0,16	0,45	disease	0,57	neutral	0,48	neutral	0,39	disease	0,54	1	neutral	0,47	deleterious	0,73	neutral	-6	neutral	0,13	medium_impact	0,58	medium_impact	0,19	medium_impact	-0,89	0,56	0,8	30,72	30,75	N	0,36	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11699	11699	A	G	MI.18298	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	940	314	I	V	Att/Gtt	-6,42	0	0	benign	0	neutral	0,35	neutral	4,44	neutral	0,54	neutral	0,39	neutral_impact	0,65	neutral	0,78	neutral	0,96	neutral	-0,61	0,12	0,24	0,45	disease	0,57	neutral	0,19	neutral	0,38	neutral	0,46	1	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,05	medium_impact	-0,48	0,5	0,8	30,72	30,75	N	0,38	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11699	11699	A	T	MI.18299	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	940	314	I	F	Att/Ttt	-6,42	0	0	benign	0,29	neutral	0,22	neutral	4,51	neutral	2,39	neutral	-1,84	low_impact	1,38	neutral	0,69	neutral	0,52	deleterious	1,92	15,69	0,12	0,4	neutral	0,42	disease	0,7	disease	0,62	disease	0,63	3	neutral	0,74	neutral	0,47	neutral	-6	neutral	0,18	medium_impact	-0,35	medium_impact	-0,11	medium_impact	0,24	0,56	0,8	30,72	30,75	N	0,35	N	0,33	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8612	8612	T	G	MI.183	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	86	29	L	R	cTa/cGa	-2,42	0	0	probably_damaging	1	deleterious	0,01	neutral	4,3	neutral	-2,99	deleterious	-4,47	medium_impact	3,19	neutral	0,78	damaging	0,14	deleterious	3,98	23,6	0,24	0,65	disease	0,75	disease	0,79	disease	0,68	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,64	0,55	0,9	17,26	17,02	N	0,27	N	0,88	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8547	8547	T	C	MI.1830	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	182	61	L	P	cTt/cCt	6,38	0,95	0	probably_damaging	0,98	neutral	0,53	neutral	2,28	neutral	0,65	neutral	6,22	neutral_impact	-2,04	neutral	0,99	neutral	0,92	deleterious	2,51	19,51	0,34743468	0,85	neutral	0,12	neutral	0,03	neutral	0,2	neutral	0,06	9	deleterious	0,98	neutral	0,28	neutral	-2	deleterious	0,61	low_impact	-2,36	medium_impact	0,32	low_impact	-2,85	0,5	0,85	NA	NA	N	0,5	N	0,07	disease_causing	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11700	11700	T	G	MI.18300	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	941	314	I	S	aTt/aGt	-0,43	0	0	benign	0,1	neutral	0,08	neutral	4,36	neutral	-1,47	neutral	-0,53	low_impact	1,76	neutral	0,74	neutral	0,65	deleterious	2,38	18,68	0,03	0,35	disease	0,73	disease	0,74	disease	0,58	disease	0,63	3	neutral	0,91	deleterious	0,49	neutral	-6	neutral	0,23	medium_impact	0,18	medium_impact	-0,39	medium_impact	0,62	0,28	0,8	30,72	30,75	N	0,38	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11700	11700	T	A	MI.18301	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	941	314	I	N	aTt/aAt	-0,43	0	0	benign	0,32	deleterious	0,01	neutral	4,33	deleterious	-3,03	neutral	-2,23	medium_impact	2,89	neutral	0,67	neutral	0,49	deleterious	2,57	19,9	0,07	0,35	disease	0,88	disease	0,77	disease	0,59	disease	0,73	5	deleterious	0,99	neutral	0,35	deleterious	1	neutral	0,27	medium_impact	-0,41	medium_impact	-0,92	medium_impact	1,73	0,33	0,8	30,72	30,75	N	0,32	N	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11700	11700	T	C	MI.18302	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	941	314	I	T	aTt/aCt	-0,43	0	0	benign	0	neutral	0,24	neutral	4,37	neutral	-0,91	neutral	0,39	low_impact	0,92	neutral	0,74	neutral	0,95	neutral	-0,1	1,71	0,07	0,35	disease	0,63	neutral	0,33	neutral	0,4	disease	0,6	2	neutral	0,76	deleterious	0,62	neutral	-6	neutral	0,15	high_impact	2,1	medium_impact	-0,08	medium_impact	-0,22	0,28	0,8	30,72	30,75	N	0,5	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11701	11701	T	A	MI.18303	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	942	314	I	M	atT/atA	0,72	0	0,01	possibly_damaging	0,56	neutral	0,18	neutral	4,41	neutral	-0,5	neutral	-0,69	neutral_impact	0,44	neutral	0,76	neutral	0,96	neutral	0,92	10,2	0,15	0,4	neutral	0,4	neutral	0,35	neutral	0,4	neutral	0,46	1	neutral	0,81	neutral	0,31	neutral	-3	neutral	0,2	medium_impact	-0,82	medium_impact	-0,17	medium_impact	-0,69	0,52	0,8	30,72	30,75	N	0,44	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11701	11701	T	G	MI.18304	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	942	314	I	M	atT/atG	0,72	0	0,01	possibly_damaging	0,56	neutral	0,18	neutral	4,41	neutral	-0,5	neutral	-0,69	neutral_impact	0,44	neutral	0,76	neutral	0,96	deleterious	0,57	7,96	0,15	0,4	neutral	0,4	neutral	0,35	neutral	0,4	neutral	0,46	1	neutral	0,81	neutral	0,31	neutral	-3	neutral	0,2	medium_impact	-0,82	medium_impact	-0,17	medium_impact	-0,69	0,52	0,8	30,72	30,75	N	0,45	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11702	11702	C	T	MI.18305	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	943	315	L	F	Ctc/Ttc	-2,96	0	0	probably_damaging	1	deleterious	0,02	neutral	4,52	neutral	-1,57	deleterious	-3,75	medium_impact	3,22	damaging	0,49	damaging	0,07	deleterious	4,08	23,7	0,2	0,45	disease	0,8	disease	0,71	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,81	low_impact	-3,54	medium_impact	-0,75	high_impact	2,06	0,44	0,8	45,1	8,68	N	0,31	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11702	11702	C	G	MI.18306	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	943	315	L	V	Ctc/Gtc	-2,96	0	0	probably_damaging	1	neutral	0,08	neutral	4,53	neutral	-1,07	deleterious	-2,8	medium_impact	2,74	damaging	0,49	damaging	0,08	deleterious	3,52	23,1	0,22	0,45	disease	0,73	disease	0,56	disease	0,64	disease	0,53	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,39	medium_impact	1,59	0,55	0,8	45,1	8,68	N	0,33	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11702	11702	C	A	MI.18307	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	943	315	L	I	Ctc/Atc	-2,96	0	0	probably_damaging	1	deleterious	0,03	neutral	4,59	neutral	-1,34	neutral	-1,88	medium_impact	2,52	damaging	0,56	damaging	0,09	deleterious	4,16	23,8	0,22	0,45	disease	0,59	disease	0,65	disease	0,62	disease	0,58	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,76	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,37	0,47	0,8	45,1	8,68	N	0,29	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11703	11703	T	G	MI.18308	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	944	315	L	R	cTc/cGc	-1,58	0	0	probably_damaging	1	deleterious	0	neutral	4,46	neutral	-2,88	deleterious	-5,63	high_impact	4,26	damaging	0,54	damaging	0,06	deleterious	4,25	23,9	0,02	0,35	disease	0,95	disease	0,86	disease	0,79	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,09	0,22	0,8	45,1	8,68	N	0,43	N	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11703	11703	T	A	MI.18309	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	944	315	L	H	cTc/cAc	-1,58	0	0	probably_damaging	1	deleterious	0	neutral	4,64	neutral	1,9	deleterious	-6,58	high_impact	4,26	damaging	0,5	damaging	0,06	deleterious	4,13	23,8	0,05	0,35	disease	0,96	disease	0,79	disease	0,75	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,09	0,24	0,8	45,1	8,68	N	0,4	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8547	8547	T	A	MI.1831	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	182	61	L	H	cTt/cAt	6,38	0,95	0	probably_damaging	0,99	neutral	0,14	neutral	1,81	deleterious	-3,32	neutral	-0,32	low_impact	1,36	neutral	0,99	neutral	0,52	deleterious	4,08	23,7	0,29361508	0,85	disease	0,66	neutral	0,24	neutral	0,49	neutral	0,18	6	deleterious	0,99	neutral	0,08	neutral	-2	deleterious	0,7	low_impact	-2,65	medium_impact	-0,15	medium_impact	0,07	0,5	0,85	NA	NA	P	0,69	P	0,45	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11703	11703	T	C	MI.18310	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	944	315	L	P	cTc/cCc	-1,58	0	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-3,69	deleterious	-6,58	high_impact	3,71	damaging	0,51	damaging	0,07	deleterious	4	23,6	0,02	0,35	disease	0,93	disease	0,79	disease	0,78	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	2,54	0,32	0,8	45,1	8,68	N	0,38	N	0,98	polymorphism	1	0,18	.	.	.	.	.	pancreatic cancer cell line	.	.	.	.	.	.	.	.	.
chrM	11705	11705	A	G	MI.18311	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	946	316	M	V	Ata/Gta	-3,42	0	0	probably_damaging	0,99	deleterious	0,01	neutral	4,56	neutral	-0,93	deleterious	-3,82	high_impact	3,6	damaging	0,51	damaging	0,07	deleterious	2,83	21,5	0,12	0,4	neutral	0,47	disease	0,84	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,67	low_impact	-2,59	medium_impact	-0,92	high_impact	2,44	0,43	0,8	46,19	9,29	N	0,32	N	0,96	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11705	11705	A	C	MI.18312	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	946	316	M	L	Ata/Cta	-3,42	0	0	probably_damaging	0,98	deleterious	0,01	neutral	4,86	neutral	0,91	deleterious	-2,87	medium_impact	3,05	damaging	0,52	damaging	0,05	deleterious	3,34	22,9	0,13	0,4	disease	0,56	disease	0,83	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,6	low_impact	-2,31	medium_impact	-0,92	medium_impact	1,89	0,4	0,8	46,19	9,29	N	0,3	N	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11705	11705	A	T	MI.18313	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	946	316	M	L	Ata/Tta	-3,42	0	0	probably_damaging	0,98	deleterious	0,01	neutral	4,86	neutral	0,91	deleterious	-2,87	medium_impact	3,05	damaging	0,52	damaging	0,05	deleterious	3,44	23	0,13	0,4	disease	0,56	disease	0,83	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,6	low_impact	-2,31	medium_impact	-0,92	medium_impact	1,89	0,4	0,8	46,19	9,29	N	0,3	N	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11706	11706	T	A	MI.18314	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	947	316	M	K	aTa/aAa	6,93	1	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-4,27	deleterious	-5,73	high_impact	4,57	damaging	0,52	damaging	0,06	deleterious	4,06	23,7	0,02	0,35	disease	0,85	disease	0,9	disease	0,78	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,4	0,23	0,8	46,19	9,29	P	0,66	P	1	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11706	11706	T	C	MI.18315	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	947	316	M	T	aTa/aCa	6,93	1	0	probably_damaging	1	deleterious	0	neutral	4,51	neutral	-2,11	deleterious	-5,73	high_impact	4,22	damaging	0,56	damaging	0,09	deleterious	3,06	22,4	0,04	0,35	disease	0,53	disease	0,85	disease	0,72	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,54	low_impact	-1,48	high_impact	3,05	0,24	0,8	46,19	9,29	P	0,59	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11707	11707	A	C	MI.18316	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	948	316	M	I	atA/atC	7,4	1	0	probably_damaging	0,99	deleterious	0,02	neutral	4,58	neutral	-0,54	deleterious	-3,82	high_impact	3,67	damaging	0,55	damaging	0,07	deleterious	3,52	23,1	0,13	0,4	neutral	0,37	disease	0,87	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-2,59	medium_impact	-0,75	high_impact	2,51	0,52	0,8	46,19	9,29	P	0,59	P	0,95	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11707	11707	A	T	MI.18317	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	948	316	M	I	atA/atT	7,4	1	0	probably_damaging	0,99	deleterious	0,02	neutral	4,58	neutral	-0,54	deleterious	-3,82	high_impact	3,67	damaging	0,55	damaging	0,07	deleterious	3,58	23,2	0,13	0,4	neutral	0,37	disease	0,87	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-2,59	medium_impact	-0,75	high_impact	2,51	0,52	0,8	46,19	9,29	P	0,6	P	0,95	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11708	11708	A	C	MI.18318	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	949	317	I	L	Atc/Ctc	2,79	1	0	benign	0,12	neutral	0,38	neutral	4,57	neutral	0,28	neutral	-1,74	low_impact	1,76	neutral	0,68	neutral	0,53	deleterious	2	16,19	0,2	0,45	neutral	0,49	disease	0,64	disease	0,55	neutral	0,41	2	neutral	0,56	deleterious	0,63	neutral	-6	neutral	0,22	medium_impact	0,1	medium_impact	0,08	medium_impact	0,62	0,56	0,8	40,09	8,05	P	0,55	P	0,86	polymorphism	1	0,03	rs386829138	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11708	11708	A	G	MI.18319	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	949	317	I	V	Atc/Gtc	2,79	1	0	benign	0,03	neutral	0,18	neutral	4,4	neutral	-0,06	neutral	-0,86	low_impact	1,02	neutral	0,81	neutral	0,88	deleterious	0,13	3,95	0,27	0,45	disease	0,54	neutral	0,26	neutral	0,49	neutral	0,36	3	neutral	0,81	deleterious	0,58	neutral	-6	neutral	0,15	medium_impact	0,7	medium_impact	-0,17	medium_impact	-0,12	0,4	0,8	40,09	8,05	P	0,5	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8549	8549	C	A	MI.1832	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	184	62	H	N	Cat/Aat	2,9	1	0	possibly_damaging	0,85	neutral	0,24	neutral	1,86	neutral	-2,44	neutral	-2,06	medium_impact	2,21	neutral	0,97	neutral	0,3	deleterious	4,77	24,7	0,86306208	0,9	disease	0,52	neutral	0,17	disease	0,62	neutral	0,13	8	neutral	0,89	neutral	0,2	NA	0	deleterious	0,56	low_impact	-1,47	medium_impact	0,01	medium_impact	0,8	0,67	0,85	NA	NA	P	0,6	P	0,62	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11708	11708	A	T	MI.18320	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	949	317	I	F	Atc/Ttc	2,79	1	0	possibly_damaging	0,75	neutral	0,06	neutral	4,35	neutral	-0,87	deleterious	-3,72	medium_impact	2,54	neutral	0,67	neutral	0,48	deleterious	2,09	16,8	0,11	0,4	disease	0,71	disease	0,82	disease	0,63	disease	0,66	3	neutral	0,95	neutral	0,16	NA	0	deleterious	0,64	low_impact	-1,17	medium_impact	-0,47	medium_impact	1,39	0,58	0,8	40,09	8,05	P	0,58	P	0,96	polymorphism	1	0,08	rs386829138	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11709	11709	T	C	MI.18321	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	950	317	I	T	aTc/aCc	3,25	1	0	possibly_damaging	0,66	deleterious	0,01	neutral	4,34	neutral	-2,4	deleterious	-4,59	medium_impact	3,28	neutral	0,65	neutral	0,51	neutral	1,71	14,45	0,04	0,35	neutral	0,4	disease	0,71	disease	0,59	disease	0,63	3	deleterious	0,99	neutral	0,18	deleterious	4	neutral	0,43	medium_impact	-0,99	medium_impact	-0,92	high_impact	2,12	0,23	0,8	40,09	8,05	N	0,48	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11709	11709	T	G	MI.18322	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	950	317	I	S	aTc/aGc	3,25	1	0	possibly_damaging	0,79	deleterious	0	neutral	4,31	deleterious	-3,21	deleterious	-5,57	high_impact	4,17	neutral	0,68	neutral	0,53	deleterious	2,61	20,3	0,02	0,35	neutral	0,45	disease	0,85	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	5	deleterious	0,51	low_impact	-1,26	low_impact	-1,48	high_impact	3	0,3	0,8	40,09	8,05	P	0,56	P	0,95	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11709	11709	T	A	MI.18323	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	950	317	I	N	aTc/aAc	3,25	1	0	probably_damaging	0,92	deleterious	0	neutral	4,29	deleterious	-4,59	deleterious	-6,53	high_impact	4,17	neutral	0,67	neutral	0,49	deleterious	3,05	22,4	0,04	0,35	disease	0,86	disease	0,83	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,74	low_impact	-1,71	low_impact	-1,48	high_impact	3	0,41	0,8	40,09	8,05	P	0,55	P	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11710	11710	C	A	MI.18324	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	951	317	I	M	atC/atA	5,78	1	0	benign	0,29	deleterious	0,03	neutral	4,36	neutral	-1,52	deleterious	-2,64	medium_impact	2,51	neutral	0,74	neutral	0,63	deleterious	2,28	18,06	0,18	0,45	disease	0,7	disease	0,67	disease	0,61	disease	0,56	1	neutral	0,97	neutral	0,37	deleterious	1	deleterious	0,6	medium_impact	-0,35	medium_impact	-0,64	medium_impact	1,36	0,45	0,8	40,09	8,05	P	0,51	P	0,76	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11710	11710	C	G	MI.18325	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	951	317	I	M	atC/atG	5,78	1	0	benign	0,29	deleterious	0,03	neutral	4,36	neutral	-1,52	deleterious	-2,64	medium_impact	2,51	neutral	0,74	neutral	0,63	deleterious	1,81	15,02	0,18	0,45	disease	0,7	disease	0,67	disease	0,61	disease	0,56	1	neutral	0,97	neutral	0,37	deleterious	1	deleterious	0,6	medium_impact	-0,35	medium_impact	-0,64	medium_impact	1,36	0,45	0,8	40,09	8,05	P	0,51	P	0,76	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11711	11711	G	C	MI.18326	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	952	318	A	P	Gcc/Ccc	-2,73	0	0	probably_damaging	1	deleterious	0	neutral	4,5	deleterious	-4,17	deleterious	-4,6	high_impact	4,33	neutral	0,61	neutral	0,33	deleterious	3,9	23,5	0,02	0,35	disease	0,88	disease	0,92	disease	0,75	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,16	0,6	0,8	46,19	8,93	N	0,44	N	0,96	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11711	11711	G	A	MI.18327	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	952	318	A	T	Gcc/Acc	-2,73	0	0	probably_damaging	1	deleterious	0,02	neutral	4,74	neutral	-0,15	deleterious	-3,58	medium_impact	3,17	neutral	0,69	neutral	0,51	deleterious	4,31	24	0,11	0,4	disease	0,56	disease	0,8	disease	0,54	disease	0,57	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,54	medium_impact	-0,75	high_impact	2,01	0,72	0,85	46,19	8,93	N	0,43	N	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11711	11711	G	T	MI.18328	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	952	318	A	S	Gcc/Tcc	-2,73	0	0	probably_damaging	1	neutral	0,3	neutral	4,68	neutral	-0,4	deleterious	-2,52	low_impact	1,44	neutral	0,67	neutral	0,6	deleterious	2,7	20,8	0,2	0,45	disease	0,57	disease	0,55	neutral	0,4	neutral	0,38	3	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	0	medium_impact	0,3	0,58	0,8	46,19	8,93	N	0,37	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11712	11712	C	T	MI.18329	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	953	318	A	V	gCc/gTc	4,86	1	0	probably_damaging	1	deleterious	0,02	neutral	4,61	neutral	-1,53	deleterious	-3,74	high_impact	3,77	neutral	0,64	neutral	0,44	deleterious	4,62	24,5	0,06	0,35	neutral	0,41	disease	0,88	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-3,54	medium_impact	-0,75	high_impact	2,6	0,76	0,85	46,19	8,93	P	0,62	P	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8549	8549	C	G	MI.1833	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	184	62	H	D	Cat/Gat	2,9	1	0	possibly_damaging	0,9	neutral	0,16	neutral	1,85	neutral	-2,55	deleterious	-3,11	medium_impact	2,56	neutral	0,97	damaging	0,19	deleterious	3,89	23,5	0,5519299	0,85	disease	0,54	neutral	0,2	disease	0,66	neutral	0,15	7	neutral	0,95	neutral	0,13	NA	0	deleterious	0,64	low_impact	-1,66	medium_impact	-0,12	medium_impact	1,1	0,63	0,85	NA	NA	P	0,59	P	0,81	polymorphism	0,99	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11712	11712	C	A	MI.18330	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	953	318	A	D	gCc/gAc	4,86	1	0	probably_damaging	1	deleterious	0	neutral	4,5	deleterious	-3,64	deleterious	-5,44	high_impact	4,33	neutral	0,66	neutral	0,38	deleterious	4,64	24,5	0,02	0,35	disease	0,92	disease	0,94	disease	0,73	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,16	0,34	0,8	46,19	8,93	P	0,61	P	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11712	11712	C	G	MI.18331	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	953	318	A	G	gCc/gGc	4,86	1	0	probably_damaging	1	neutral	0,37	neutral	4,55	neutral	-2,75	deleterious	-3,65	medium_impact	2,05	neutral	0,66	neutral	0,53	deleterious	4,12	23,8	0,16	0,45	disease	0,85	disease	0,76	disease	0,59	disease	0,62	2	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,07	medium_impact	0,9	0,62	0,8	46,19	8,93	P	0,56	P	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11714	11714	C	A	MI.18332	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	955	319	H	N	Cac/Aac	-3,19	0	0	probably_damaging	1	deleterious	0	neutral	3,89	deleterious	-6,23	deleterious	-6,66	high_impact	4,25	damaging	0,59	damaging	0,1	deleterious	4,03	23,6	0,09	0,35	disease	0,78	disease	0,84	disease	0,78	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,08	0,24	0,8	47,71	9,36	N	0,41	N	0,97	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11714	11714	C	G	MI.18333	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	955	319	H	D	Cac/Gac	-3,19	0	0	probably_damaging	1	deleterious	0	neutral	3,89	deleterious	-6,85	deleterious	-8,57	high_impact	4,6	neutral	0,67	damaging	0,1	deleterious	3,97	23,6	0,04	0,35	disease	0,77	disease	0,88	disease	0,83	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,43	0,16	0,8	47,71	9,36	N	0,52	P	0,97	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11714	11714	C	T	MI.18334	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	955	319	H	Y	Cac/Tac	-3,19	0	0	probably_damaging	1	deleterious	0	neutral	4,25	neutral	-1,26	deleterious	-5,72	high_impact	4,25	neutral	0,63	damaging	0,09	deleterious	3,85	23,4	0,05	0,35	disease	0,7	disease	0,89	disease	0,76	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,08	0,26	0,8	47,71	9,36	N	0,4	N	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11715	11715	A	T	MI.18335	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	956	319	H	L	cAc/cTc	7,17	1	0	probably_damaging	1	deleterious	0	neutral	3,95	deleterious	-3,82	deleterious	-10,48	high_impact	4,6	damaging	0,59	damaging	0,09	deleterious	3,99	23,6	0,03	0,35	disease	0,55	disease	0,92	disease	0,78	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,43	0,2	0,8	47,71	9,36	P	0,66	P	0,96	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11715	11715	A	C	MI.18336	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	956	319	H	P	cAc/cCc	7,17	1	0	probably_damaging	1	deleterious	0	neutral	3,88	deleterious	-7,23	deleterious	-9,53	high_impact	4,6	neutral	0,62	damaging	0,09	deleterious	3,39	23	0,03	0,35	disease	0,82	disease	0,9	disease	0,86	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,43	0,14	0,8	47,71	9,36	P	0,64	P	0,95	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11715	11715	A	G	MI.18337	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	956	319	H	R	cAc/cGc	7,17	1	0	probably_damaging	1	deleterious	0	neutral	3,89	deleterious	-6,28	deleterious	-7,61	high_impact	4,6	damaging	0,6	damaging	0,11	deleterious	3,14	22,6	0,03	0,35	disease	0,75	disease	0,9	disease	0,82	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,43	0,31	0,8	47,71	9,36	P	0,65	P	0,97	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11716	11716	C	A	MI.18338	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	957	319	H	Q	caC/caA	8,55	1	0	probably_damaging	1	deleterious	0	neutral	3,97	deleterious	-3,46	deleterious	-7,6	high_impact	3,7	neutral	0,62	damaging	0,1	deleterious	4,02	23,6	0,04	0,35	disease	0,77	disease	0,85	disease	0,79	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,53	0,24	0,8	47,71	9,36	P	0,64	P	0,93	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11716	11716	C	G	MI.18339	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	957	319	H	Q	caC/caG	8,55	1	0	probably_damaging	1	deleterious	0	neutral	3,97	deleterious	-3,46	deleterious	-7,6	high_impact	3,7	neutral	0,62	damaging	0,1	deleterious	3,64	23,2	0,04	0,35	disease	0,77	disease	0,85	disease	0,79	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,53	0,24	0,8	47,71	9,36	P	0,64	P	0,93	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8549	8549	C	T	MI.1834	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	184	62	H	Y	Cat/Tat	2,9	1	0	possibly_damaging	0,85	neutral	1	neutral	1,84	neutral	-2,06	neutral	-0,57	medium_impact	2	neutral	0,97	neutral	0,4	deleterious	3,59	23,2	0,82750062	0,9	neutral	0,37	neutral	0,17	disease	0,54	neutral	0,13	8	neutral	0,85	deleterious	0,58	NA	0	deleterious	0,56	low_impact	-1,47	high_impact	1,98	medium_impact	0,62	0,33	0,85	NA	NA	N	0,44	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11717	11717	G	C	MI.18340	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	958	320	G	R	Ggg/Cgg	-4,81	0	0	probably_damaging	1	deleterious	0	neutral	4,42	deleterious	-4,07	deleterious	-7,6	high_impact	4,55	damaging	0,42	damaging	0,02	deleterious	4,05	23,7	0,02	0,35	disease	0,87	disease	0,91	disease	0,78	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,38	0,21	0,8	46,62	8,84	P	0,56	P	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11717	11717	G	T	MI.18341	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	958	320	G	W	Ggg/Tgg	-4,81	0	0	probably_damaging	1	deleterious	0	neutral	4,4	deleterious	-5,99	deleterious	-7,61	high_impact	4,55	damaging	0,39	damaging	0,02	deleterious	4,51	24,3	0,03	0,35	neutral	0,4	disease	0,92	disease	0,73	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,54	low_impact	-1,48	high_impact	3,38	0,14	0,8	46,62	8,84	N	0,49	N	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11718	11718	G	A	MI.18342	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	959	320	G	E	gGg/gAg	9,01	1	0	probably_damaging	1	deleterious	0	neutral	4,42	deleterious	-3,8	deleterious	-7,6	high_impact	4,55	damaging	0,36	damaging	0,03	deleterious	3,99	23,6	0,02	0,35	disease	0,89	disease	0,9	disease	0,77	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	3,38	0,26	0,8	46,62	8,84	P	0,76	P	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11718	11718	G	T	MI.18343	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	959	320	G	V	gGg/gTg	9,01	1	0	probably_damaging	1	deleterious	0	neutral	4,53	neutral	-1,98	deleterious	-8,55	high_impact	4,55	damaging	0,4	damaging	0,03	deleterious	3,9	23,5	0,02	0,35	neutral	0,49	disease	0,9	disease	0,68	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	3,38	0,15	0,8	46,62	8,84	P	0,7	P	0,98	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11718	11718	G	C	MI.18344	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	959	320	G	A	gGg/gCg	9,01	1	0	probably_damaging	1	deleterious	0,02	neutral	4,68	neutral	0,7	deleterious	-5,68	medium_impact	2,92	damaging	0,48	damaging	0,07	deleterious	3,22	22,7	0,12	0,4	disease	0,59	disease	0,73	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,76	0,44	0,8	46,62	8,84	P	0,58	P	0,76	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11720	11720	C	T	MI.18345	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	961	321	L	F	Ctt/Ttt	-11,71	0	0	probably_damaging	1	neutral	0,12	neutral	4,69	neutral	-0,4	deleterious	-3,64	low_impact	1,7	damaging	0,52	damaging	0,17	deleterious	4,07	23,7	0,22	0,45	disease	0,57	disease	0,64	neutral	0,43	neutral	0,37	3	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	-0,28	medium_impact	0,56	0,56	0,8	44,01	8,04	N	0,36	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11720	11720	C	G	MI.18346	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	961	321	L	V	Ctt/Gtt	-11,71	0	0	probably_damaging	1	deleterious	0,02	neutral	4,51	neutral	-1,64	deleterious	-2,82	medium_impact	2,58	damaging	0,54	damaging	0,07	deleterious	3,57	23,1	0,25	0,45	disease	0,67	disease	0,63	disease	0,56	disease	0,51	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,77	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,43	0,55	0,8	44,01	8,04	N	0,26	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11720	11720	C	A	MI.18347	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	961	321	L	I	Ctt/Att	-11,71	0	0	probably_damaging	1	neutral	0,12	neutral	4,45	neutral	-1,21	neutral	-1,87	medium_impact	2	damaging	0,56	damaging	0,11	deleterious	4,25	23,9	0,3	0,45	disease	0,62	disease	0,65	disease	0,53	neutral	0,39	2	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,28	medium_impact	0,85	0,59	0,8	44,01	8,04	N	0,31	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11721	11721	T	A	MI.18348	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	962	321	L	H	cTt/cAt	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	4,35	deleterious	-5,61	deleterious	-6,57	high_impact	4,38	damaging	0,5	damaging	0,04	deleterious	4,21	23,9	0,03	0,35	disease	0,96	disease	0,83	disease	0,72	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,21	0,33	0,8	44,01	8,04	N	0,38	N	0,96	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11721	11721	T	G	MI.18349	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	962	321	L	R	cTt/cGt	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	4,36	deleterious	-5,09	deleterious	-5,66	high_impact	4,38	damaging	0,55	damaging	0,04	deleterious	4,31	24	0,02	0,35	disease	0,94	disease	0,9	disease	0,75	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,21	0,15	0,8	44,01	8,04	N	0,4	N	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8550	8550	A	G	MI.1835	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	185	62	H	R	cAt/cGt	5,22	1	0	possibly_damaging	0,9	neutral	0,35	neutral	1,87	neutral	-1,9	neutral	-1,88	medium_impact	2,56	neutral	0,97	damaging	0,18	deleterious	1,9	15,6	0,85853464	0,9	neutral	0,42	neutral	0,15	disease	0,61	neutral	0,11	8	neutral	0,91	neutral	0,23	NA	0	deleterious	0,62	low_impact	-1,66	medium_impact	0,14	medium_impact	1,1	0,26	0,85	NA	NA	P	0,64	P	0,58	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11721	11721	T	C	MI.18350	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	962	321	L	P	cTt/cCt	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	4,35	deleterious	-5,61	deleterious	-6,62	high_impact	4,03	damaging	0,5	damaging	0,04	deleterious	3,99	23,6	0,02	0,35	disease	0,96	disease	0,85	disease	0,74	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	2,86	0,39	0,8	44,01	8,04	N	0,33	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11723	11723	A	G	MI.18351	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	964	322	T	A	Aca/Gca	-16,09	0	0	probably_damaging	1	neutral	0,18	neutral	4,59	neutral	0,29	deleterious	-3,78	medium_impact	2,78	neutral	0,74	damaging	0,25	deleterious	2,34	18,44	0,25	0,45	neutral	0,43	disease	0,54	neutral	0,41	neutral	0,39	2	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,7	low_impact	-3,54	medium_impact	-0,17	medium_impact	1,62	0,46	0,8	46,84	9,51	N	0,37	N	0,69	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11723	11723	A	C	MI.18352	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	964	322	T	P	Aca/Cca	-16,09	0	0	probably_damaging	1	deleterious	0,01	neutral	4,53	deleterious	-3,71	deleterious	-5	high_impact	3,98	neutral	0,65	damaging	0,13	deleterious	3,58	23,2	0,05	0,35	disease	0,85	disease	0,9	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,54	medium_impact	-0,92	high_impact	2,81	0,35	0,8	46,84	9,51	N	0,31	N	0,97	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11723	11723	A	T	MI.18353	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	964	322	T	S	Aca/Tca	-16,09	0	0	probably_damaging	1	neutral	0,42	neutral	4,67	neutral	-0,07	deleterious	-3,32	low_impact	1,84	neutral	0,75	damaging	0,22	deleterious	3,34	22,9	0,34	0,5	neutral	0,43	disease	0,71	neutral	0,38	neutral	0,48	0	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	0,12	medium_impact	0,69	0,65	0,8	46,84	9,51	N	0,32	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11724	11724	C	A	MI.18354	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	965	322	T	K	aCa/aAa	3,94	0,91	0	probably_damaging	1	deleterious	0,01	neutral	4,54	deleterious	-3,06	deleterious	-5	high_impact	3,98	neutral	0,7	damaging	0,13	deleterious	4,51	24,3	0,06	0,35	disease	0,72	disease	0,91	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-3,54	medium_impact	-0,92	high_impact	2,81	0,5	0,8	46,84	9,51	N	0,46	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11724	11724	C	T	MI.18355	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	965	322	T	M	aCa/aTa	3,94	0,91	0	probably_damaging	1	deleterious	0	neutral	4,66	neutral	-0,17	deleterious	-4,51	medium_impact	3,43	neutral	0,74	damaging	0,16	deleterious	4,09	23,7	0,11	0,4	disease	0,69	disease	0,8	disease	0,58	disease	0,66	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,75	low_impact	-3,54	low_impact	-1,48	high_impact	2,27	0,53	0,8	46,84	9,51	N	0,44	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11726	11726	T	A	MI.18356	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	967	323	S	T	Tcc/Acc	-7,57	0	0	probably_damaging	1	deleterious	0	neutral	4,47	neutral	0	deleterious	-2,87	medium_impact	2,98	damaging	0,45	damaging	0,07	deleterious	3,91	23,5	0,22	0,45	neutral	0,49	disease	0,7	disease	0,65	disease	0,66	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,75	low_impact	-3,54	low_impact	-1,48	medium_impact	1,82	0,46	0,8	47,06	9,41	N	0,37	N	0,73	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11726	11726	T	C	MI.18357	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	967	323	S	P	Tcc/Ccc	-7,57	0	0	probably_damaging	1	deleterious	0	neutral	4,4	deleterious	-3,34	deleterious	-4,78	high_impact	4,24	damaging	0,36	damaging	0,05	deleterious	4,09	23,7	0,04	0,35	disease	0,8	disease	0,86	disease	0,77	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,07	0,19	0,8	47,06	9,41	P	0,57	P	0,99	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11726	11726	T	G	MI.18358	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	967	323	S	A	Tcc/Gcc	-7,57	0	0	probably_damaging	1	neutral	0,06	neutral	4,46	neutral	-0,77	deleterious	-2,87	medium_impact	3	damaging	0,46	damaging	0,14	deleterious	3,8	23,4	0,2	0,45	disease	0,5	disease	0,6	disease	0,6	disease	0,64	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,84	0,37	0,8	47,06	9,41	N	0,39	N	0,51	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11727	11727	C	G	MI.18359	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	968	323	S	C	tCc/tGc	7,4	1	0	probably_damaging	1	deleterious	0	neutral	4,39	deleterious	-4,64	deleterious	-4,78	high_impact	4,58	damaging	0,39	damaging	0,03	deleterious	3,66	23,2	0,07	0,35	disease	0,89	disease	0,82	disease	0,64	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	3,41	0,28	0,8	47,06	9,41	P	0,7	P	1	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8550	8550	A	C	MI.1836	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	185	62	H	P	cAt/cCt	5,22	1	0	probably_damaging	0,94	neutral	0,2	neutral	1,85	deleterious	-3,5	neutral	-1,76	low_impact	0,85	neutral	0,98	neutral	0,61	deleterious	2,18	17,4	0,47136521	0,85	disease	0,65	neutral	0,34	disease	0,51	neutral	0,26	5	neutral	0,96	neutral	0,13	neutral	-2	deleterious	0,72	low_impact	-1,89	medium_impact	-0,05	medium_impact	-0,37	0,38	0,85	NA	NA	P	0,65	P	0,81	polymorphism	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11727	11727	C	T	MI.18360	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	968	323	S	F	tCc/tTc	7,4	1	0	probably_damaging	1	deleterious	0	neutral	4,39	deleterious	-3,69	deleterious	-5,73	high_impact	4,58	damaging	0,41	damaging	0,03	deleterious	4,3	24	0,07	0,35	disease	0,64	disease	0,9	disease	0,64	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,41	0,12	0,8	47,06	9,41	P	0,68	P	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11727	11727	C	A	MI.18361	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	968	323	S	Y	tCc/tAc	7,4	1	0	probably_damaging	1	deleterious	0	neutral	4,4	deleterious	-3,67	deleterious	-5,73	high_impact	4,58	damaging	0,39	damaging	0,04	deleterious	4,3	24	0,06	0,35	disease	0,7	disease	0,88	disease	0,68	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,41	0,2	0,8	47,06	9,41	P	0,73	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11729	11729	T	A	MI.18362	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	970	324	S	T	Tca/Aca	-12,86	0	0	probably_damaging	1	neutral	0,07	neutral	4,58	neutral	-1,19	deleterious	-2,81	high_impact	3,54	damaging	0,45	damaging	0,08	deleterious	3,91	23,5	0,23	0,45	disease	0,56	disease	0,71	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,75	low_impact	-3,54	medium_impact	-0,43	high_impact	2,38	0,44	0,8	45,97	8,92	N	0,36	N	0,73	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11729	11729	T	C	MI.18363	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	970	324	S	P	Tca/Cca	-12,86	0	0	probably_damaging	1	neutral	0,05	neutral	4,47	deleterious	-3,22	deleterious	-4,75	medium_impact	2,6	damaging	0,35	damaging	0,08	deleterious	4,09	23,7	0,04	0,35	disease	0,86	disease	0,85	disease	0,76	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,45	0,33	0,8	45,97	8,92	N	0,5	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11729	11729	T	G	MI.18364	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	970	324	S	A	Tca/Gca	-12,86	0	0	probably_damaging	1	neutral	0,07	neutral	4,77	neutral	1,5	deleterious	-2,85	medium_impact	2,61	damaging	0,46	damaging	0,11	deleterious	3,79	23,4	0,24	0,45	disease	0,54	disease	0,6	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	-0,43	medium_impact	1,46	0,41	0,8	45,97	8,92	N	0,37	N	0,51	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11730	11730	C	T	MI.18365	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	971	324	S	L	tCa/tTa	5,78	1	0	probably_damaging	1	deleterious	0	neutral	4,66	neutral	-0,94	deleterious	-5,69	high_impact	4,17	damaging	0,42	damaging	0,03	deleterious	4,76	24,7	0,05	0,35	neutral	0,35	disease	0,88	disease	0,63	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,54	low_impact	-1,48	high_impact	3	0,35	0,8	45,97	8,92	P	0,68	P	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11730	11730	C	G	MI.18366	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	971	324	S	W	tCa/tGa	5,78	1	0	probably_damaging	1	deleterious	0	neutral	4,47	deleterious	-5,19	deleterious	-6,65	high_impact	4,51	damaging	0,43	damaging	0,04	deleterious	4,46	24,2	0,06	0,35	disease	0,87	disease	0,88	disease	0,69	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,34	0,14	0,8	45,97	8,92	P	0,67	P	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11732	11732	T	A	MI.18367	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	973	325	L	M	Tta/Ata	-11,94	0	0	benign	0,15	neutral	0,45	neutral	4,48	neutral	-2,68	neutral	0,72	neutral_impact	-0,92	neutral	0,78	neutral	0,96	neutral	1,75	14,67	0,26	0,45	disease	0,57	neutral	0,05	neutral	0,24	neutral	0,4	2	neutral	0,47	deleterious	0,65	neutral	-6	deleterious	0,68	medium_impact	-0,01	medium_impact	0,15	low_impact	-2,04	0,55	0,8	20,7	16,06	N	0,35	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11732	11732	T	G	MI.18368	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	973	325	L	V	Tta/Gta	-11,94	0	0	possibly_damaging	0,53	neutral	0,15	neutral	4,48	neutral	-2,38	neutral	-0,92	low_impact	1,01	neutral	0,82	neutral	0,95	neutral	1,13	11,4	0,26	0,45	disease	0,52	neutral	0,35	neutral	0,32	neutral	0,35	3	neutral	0,84	neutral	0,31	neutral	-3	deleterious	0,71	medium_impact	-0,77	medium_impact	-0,22	medium_impact	-0,13	0,57	0,8	20,7	16,06	N	0,43	N	0,39	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11733	11733	T	G	MI.18369	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	974	325	L	W	tTa/tGa	-0,2	0	0	probably_damaging	0,98	deleterious	0,01	neutral	4,39	deleterious	-6,39	deleterious	-3,52	medium_impact	2,5	neutral	0,73	neutral	0,47	deleterious	3,82	23,4	0,04	0,35	disease	0,93	disease	0,63	disease	0,55	disease	0,78	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,82	low_impact	-2,31	medium_impact	-0,92	medium_impact	1,35	0,26	0,8	20,7	16,06	N	0,34	N	0,82	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8550	8550	A	T	MI.1837	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	185	62	H	L	cAt/cTt	5,22	1	0	possibly_damaging	0,9	neutral	0,94	neutral	2,06	neutral	-0,05	neutral	0,72	neutral_impact	-0,26	neutral	0,98	neutral	0,9	neutral	1,03	10,83	0,63281019	0,85	neutral	0,1	neutral	0,09	neutral	0,36	neutral	0,04	9	neutral	0,89	deleterious	0,52	neutral	-3	deleterious	0,58	low_impact	-1,66	medium_impact	0,97	low_impact	-1,32	0,32	0,85	NA	NA	P	0,54	P	0,14	polymorphism	0,98	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11733	11733	T	C	MI.18370	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	974	325	L	S	tTa/tCa	-0,2	0	0	possibly_damaging	0,86	neutral	0,09	neutral	4,5	neutral	-2,71	deleterious	-2,64	low_impact	1,01	neutral	0,73	neutral	0,74	deleterious	2,73	21	0,05	0,35	neutral	0,35	neutral	0,48	neutral	0,34	neutral	0,46	1	neutral	0,96	neutral	0,12	neutral	-3	deleterious	0,71	low_impact	-1,46	medium_impact	-0,36	medium_impact	-0,13	0,28	0,8	20,7	16,06	N	0,41	N	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11734	11734	A	T	MI.18371	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	975	325	L	F	ttA/ttT	3,25	0,1	0	possibly_damaging	0,76	neutral	0,13	neutral	4,42	deleterious	-3,92	neutral	-2,23	low_impact	1,7	neutral	0,68	neutral	0,65	deleterious	3,62	23,2	0,17	0,45	disease	0,59	disease	0,56	disease	0,52	disease	0,58	2	neutral	0,91	neutral	0,19	neutral	-3	deleterious	0,75	low_impact	-1,19	medium_impact	-0,26	medium_impact	0,56	0,54	0,8	20,7	16,06	N	0,46	N	0,44	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11734	11734	A	C	MI.18372	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	975	325	L	F	ttA/ttC	3,25	0,1	0	possibly_damaging	0,76	neutral	0,13	neutral	4,42	deleterious	-3,92	neutral	-2,23	low_impact	1,7	neutral	0,68	neutral	0,65	deleterious	3,48	23,1	0,17	0,45	disease	0,59	disease	0,56	disease	0,52	disease	0,58	2	neutral	0,91	neutral	0,19	neutral	-3	deleterious	0,75	low_impact	-1,19	medium_impact	-0,26	medium_impact	0,56	0,54	0,8	20,7	16,06	N	0,45	N	0,44	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11735	11735	C	A	MI.18373	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	976	326	L	M	Cta/Ata	-0,2	0	0	possibly_damaging	0,61	neutral	0,18	neutral	4,18	deleterious	-3,89	neutral	-1,72	low_impact	1,79	neutral	0,66	neutral	0,64	deleterious	3,8	23,4	0,14	0,4	disease	0,85	neutral	0,49	disease	0,55	disease	0,59	2	neutral	0,83	neutral	0,29	neutral	-3	deleterious	0,75	medium_impact	-0,9	medium_impact	-0,17	medium_impact	0,65	0,5	0,8	12,42	12,51	N	0,37	N	0,62	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11735	11735	C	G	MI.18374	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	976	326	L	V	Cta/Gta	-0,2	0	0	possibly_damaging	0,81	deleterious	0	neutral	4,2	deleterious	-3,91	deleterious	-2,78	high_impact	4,47	damaging	0,56	neutral	0,5	deleterious	3,51	23,1	0,09	0,35	disease	0,75	disease	0,58	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,1	deleterious	5	deleterious	0,76	low_impact	-1,31	low_impact	-1,48	high_impact	3,3	0,54	0,8	12,42	12,51	P	0,53	P	0,53	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11736	11736	T	G	MI.18375	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	977	326	L	R	cTa/cGa	-1,35	0	0,01	probably_damaging	0,98	deleterious	0	neutral	4,07	deleterious	-6,6	deleterious	-5,6	high_impact	4,47	damaging	0,54	neutral	0,37	deleterious	4,24	23,9	0,02	0,35	disease	0,55	disease	0,85	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,31	low_impact	-1,48	high_impact	3,3	0,19	0,8	12,42	12,51	N	0,48	N	0,97	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11736	11736	T	C	MI.18376	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	977	326	L	P	cTa/cCa	-1,35	0	0,01	probably_damaging	0,98	deleterious	0	neutral	4,06	deleterious	-7,17	deleterious	-6,55	high_impact	4,47	damaging	0,48	neutral	0,46	deleterious	4,09	23,7	0,02	0,35	disease	0,82	disease	0,82	disease	0,74	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,31	low_impact	-1,48	high_impact	3,3	0,31	0,8	12,42	12,51	N	0,49	N	0,93	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11736	11736	T	A	MI.18377	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	977	326	L	Q	cTa/cAa	-1,35	0	0,01	probably_damaging	0,98	deleterious	0	neutral	4,06	deleterious	-6,77	deleterious	-5,56	high_impact	4,47	damaging	0,54	neutral	0,45	deleterious	4,35	24,1	0,03	0,35	disease	0,58	disease	0,84	disease	0,64	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,31	low_impact	-1,48	high_impact	3,3	0,31	0,8	12,42	12,51	N	0,46	N	0,93	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11738	11738	T	G	MI.18378	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	979	327	F	V	Ttc/Gtc	-0,43	0,3	0	probably_damaging	1	deleterious	0	neutral	2,64	deleterious	-7,46	deleterious	-6,63	high_impact	4,25	damaging	0,47	neutral	0,65	deleterious	4,15	23,8	0,04	0,35	disease	0,63	disease	0,84	disease	0,75	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	3,08	0,24	0,8	47,06	9,31	P	0,54	P	0,84	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11738	11738	T	A	MI.18379	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	979	327	F	I	Ttc/Atc	-0,43	0,3	0	probably_damaging	1	deleterious	0	neutral	2,65	deleterious	-7,21	deleterious	-5,68	high_impact	4,59	damaging	0,51	neutral	0,75	deleterious	4,49	24,3	0,05	0,35	disease	0,69	disease	0,83	disease	0,76	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,37	0,8	47,06	9,31	P	0,56	P	0,74	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8551	8551	T	A	MI.1838	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	186	62	H	Q	caT/caA	0,59	0,99	0	probably_damaging	0,94	neutral	0,23	neutral	1,86	neutral	-2,2	neutral	-1,84	medium_impact	2,56	neutral	0,97	damaging	0,23	deleterious	4,17	23,8	0,90489867	0,95	neutral	0,48	neutral	0,2	disease	0,64	neutral	0,14	7	neutral	0,96	neutral	0,15	deleterious	1	deleterious	0,62	low_impact	-1,89	medium_impact	-0,01	medium_impact	1,1	0,57	0,85	NA	NA	N	0,53	P	0,64	polymorphism	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11738	11738	T	C	MI.18380	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	979	327	F	L	Ttc/Ctc	-0,43	0,3	0	probably_damaging	1	deleterious	0	neutral	2,74	deleterious	-5,12	deleterious	-5,68	medium_impact	3,44	damaging	0,46	neutral	0,67	deleterious	4,12	23,8	0,03	0,35	disease	0,64	disease	0,82	disease	0,69	disease	0,7	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	2,28	0,4	0,8	47,06	9,31	N	0,47	N	0,78	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11739	11739	T	C	MI.18381	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	980	327	F	S	tTc/tCc	7,4	1	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-9	deleterious	-7,58	high_impact	4,59	damaging	0,46	neutral	0,79	deleterious	4,41	24,1	0,01	0,35	disease	0,65	disease	0,87	disease	0,72	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,2	0,8	47,06	9,31	P	0,59	P	0,11	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11739	11739	T	G	MI.18382	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	980	327	F	C	tTc/tGc	7,4	1	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-10,27	deleterious	-7,58	high_impact	4,25	damaging	0,54	neutral	0,58	deleterious	4,18	23,8	0,02	0,35	disease	0,81	disease	0,87	disease	0,73	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,54	low_impact	-1,48	high_impact	3,08	0,12	0,8	47,06	9,31	P	0,52	P	0,85	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11739	11739	T	A	MI.18383	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	980	327	F	Y	tTc/tAc	7,4	1	0	probably_damaging	1	deleterious	0	neutral	2,69	deleterious	-5,93	deleterious	-2,85	high_impact	4,59	damaging	0,52	neutral	0,58	deleterious	4,54	24,3	0,08	0,35	disease	0,68	disease	0,8	disease	0,75	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,46	0,8	47,06	9,31	P	0,61	P	0,65	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11740	11740	C	G	MI.18384	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	981	327	F	L	ttC/ttG	5,78	1	0	probably_damaging	1	deleterious	0	neutral	2,74	deleterious	-5,12	deleterious	-5,68	medium_impact	3,44	damaging	0,46	neutral	0,67	deleterious	4,49	24,3	0,03	0,35	disease	0,64	disease	0,82	disease	0,69	disease	0,7	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	2,28	0,4	0,8	47,06	9,31	P	0,63	P	0,78	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11740	11740	C	A	MI.18385	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	981	327	F	L	ttC/ttA	5,78	1	0	probably_damaging	1	deleterious	0	neutral	2,74	deleterious	-5,12	deleterious	-5,68	medium_impact	3,44	damaging	0,46	neutral	0,67	deleterious	4,72	24,6	0,03	0,35	disease	0,64	disease	0,82	disease	0,69	disease	0,7	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	2,28	0,4	0,8	47,06	9,31	P	0,63	P	0,78	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11741	11741	T	A	MI.18386	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	982	328	C	S	Tgc/Agc	-0,66	0,13	0	probably_damaging	1	neutral	0,05	neutral	4,66	neutral	0,01	deleterious	-8,92	medium_impact	2,12	neutral	0,6	neutral	0,62	deleterious	3,58	23,2	0,09	0,35	neutral	0,47	disease	0,88	disease	0,64	disease	0,63	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,52	medium_impact	0,97	0,53	0,8	46,19	8,87	N	0,44	N	0,24	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11741	11741	T	G	MI.18387	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	982	328	C	G	Tgc/Ggc	-0,66	0,13	0	probably_damaging	1	deleterious	0,01	neutral	4,64	neutral	-0,88	deleterious	-10,84	high_impact	3,57	neutral	0,6	neutral	0,57	deleterious	3,36	22,9	0,08	0,35	disease	0,63	disease	0,9	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,54	medium_impact	-0,92	high_impact	2,41	0,36	0,8	46,19	8,87	N	0,42	N	0,75	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11741	11741	T	C	MI.18388	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	982	328	C	R	Tgc/Cgc	-0,66	0,13	0	probably_damaging	1	deleterious	0,01	neutral	4,62	neutral	-1,73	deleterious	-10,76	high_impact	4,26	damaging	0,6	neutral	0,45	deleterious	3,58	23,2	0,05	0,35	disease	0,58	disease	0,92	disease	0,79	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,54	medium_impact	-0,92	high_impact	3,09	0,14	0,8	46,19	8,87	P	0,55	P	0,87	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11742	11742	G	A	MI.18389	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	983	328	C	Y	tGc/tAc	5,55	1	0	probably_damaging	1	neutral	0,27	neutral	4,65	neutral	-0,23	deleterious	-9,94	medium_impact	2,36	neutral	0,61	neutral	0,42	deleterious	3,73	23,3	0,09	0,35	disease	0,57	disease	0,93	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	-0,04	medium_impact	1,21	0,34	0,8	46,19	8,87	P	0,53	P	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8551	8551	T	G	MI.1839	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	186	62	H	Q	caT/caG	0,59	0,99	0	probably_damaging	0,94	neutral	0,23	neutral	1,86	neutral	-2,2	neutral	-1,84	medium_impact	2,56	neutral	0,97	damaging	0,23	deleterious	3,86	23,5	0,90489867	0,95	neutral	0,48	neutral	0,2	disease	0,64	neutral	0,14	7	neutral	0,96	neutral	0,15	deleterious	1	deleterious	0,62	low_impact	-1,89	medium_impact	-0,01	medium_impact	1,1	0,57	0,85	NA	NA	N	0,53	P	0,64	polymorphism	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11742	11742	G	T	MI.18390	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	983	328	C	F	tGc/tTc	5,55	1	0	probably_damaging	1	neutral	0,12	neutral	4,71	neutral	1,53	deleterious	-9,95	medium_impact	2,04	neutral	0,62	neutral	0,48	deleterious	4,01	23,6	0,11	0,4	disease	0,51	disease	0,93	disease	0,68	disease	0,67	3	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	-0,28	medium_impact	0,89	0,28	0,8	46,19	8,87	P	0,55	P	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11742	11742	G	C	MI.18391	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	983	328	C	S	tGc/tCc	5,55	1	0	probably_damaging	1	neutral	0,05	neutral	4,66	neutral	0,01	deleterious	-8,92	medium_impact	2,12	neutral	0,6	neutral	0,62	deleterious	3,29	22,8	0,09	0,35	neutral	0,47	disease	0,88	disease	0,64	disease	0,63	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,52	medium_impact	0,97	0,53	0,8	46,19	8,87	P	0,56	P	0,24	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11743	11743	C	A	MI.18392	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	984	328	C	W	tgC/tgA	6,01	1	0	probably_damaging	1	deleterious	0	neutral	4,61	neutral	-1,96	deleterious	-9,95	high_impact	4,26	damaging	0,58	neutral	0,45	deleterious	4,73	24,6	0,05	0,35	neutral	0,46	disease	0,93	disease	0,76	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	3,09	0,29	0,8	46,19	8,87	P	0,62	P	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11743	11743	C	G	MI.18393	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	984	328	C	W	tgC/tgG	6,01	1	0	probably_damaging	1	deleterious	0	neutral	4,61	neutral	-1,96	deleterious	-9,95	high_impact	4,26	damaging	0,58	neutral	0,45	deleterious	4,4	24,1	0,05	0,35	neutral	0,46	disease	0,93	disease	0,76	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	3,09	0,29	0,8	46,19	8,87	P	0,62	P	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11744	11744	C	A	MI.18394	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	985	329	L	M	Cta/Ata	-1,58	0	0	probably_damaging	1	deleterious	0,04	neutral	4,34	neutral	-2,19	neutral	-1,89	medium_impact	2,69	damaging	0,51	damaging	0,13	deleterious	3,81	23,4	0,31	0,45	disease	0,52	disease	0,54	disease	0,68	disease	0,55	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,73	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,54	0,71	0,85	46,62	9,16	N	0,35	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11744	11744	C	G	MI.18395	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	985	329	L	V	Cta/Gta	-1,58	0	0	probably_damaging	1	neutral	0,05	neutral	4,45	neutral	-0,29	deleterious	-2,83	medium_impact	2,98	damaging	0,48	damaging	0,13	deleterious	3,54	23,1	0,23	0,45	disease	0,52	disease	0,54	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,82	0,63	0,8	46,62	9,16	N	0,39	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11745	11745	T	G	MI.18396	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	986	329	L	R	cTa/cGa	-1,81	0	0	probably_damaging	1	deleterious	0	neutral	4,32	deleterious	-4,15	deleterious	-5,68	high_impact	4,46	damaging	0,42	damaging	0,09	deleterious	4,29	24	0,02	0,35	neutral	0,42	disease	0,82	disease	0,79	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,29	0,31	0,8	46,62	9,16	P	0,59	P	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11745	11745	T	A	MI.18397	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	986	329	L	Q	cTa/cAa	-1,81	0	0	probably_damaging	1	deleterious	0	neutral	4,37	deleterious	-4,25	deleterious	-5,68	high_impact	3,9	damaging	0,43	damaging	0,11	deleterious	4,18	23,8	0,04	0,35	neutral	0,31	disease	0,83	disease	0,69	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,54	low_impact	-1,48	high_impact	2,73	0,35	0,8	46,62	9,16	N	0,45	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11745	11745	T	C	MI.18398	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	986	329	L	P	cTa/cCa	-1,81	0	0	probably_damaging	1	deleterious	0	neutral	4,31	deleterious	-4,75	deleterious	-6,63	high_impact	4,46	damaging	0,39	damaging	0,11	deleterious	4,02	23,6	0,03	0,35	disease	0,62	disease	0,78	disease	0,78	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,29	0,28	0,8	46,62	9,16	P	0,62	P	0,98	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11747	11747	G	C	MI.18399	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	988	330	A	P	Gca/Cca	-0,2	0,54	0	probably_damaging	1	deleterious	0	neutral	4,34	deleterious	-5,96	deleterious	-4,74	high_impact	4,36	neutral	0,69	damaging	0,08	deleterious	3,93	23,5	0,02	0,35	neutral	0,23	disease	0,83	disease	0,81	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,54	low_impact	-1,48	high_impact	3,19	0,64	0,8	47,28	9,3	N	0,54	P	0,96	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8612	8612	T	A	MI.184	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	86	29	L	Q	cTa/cAa	-2,42	0	0	probably_damaging	1	deleterious	0,01	neutral	4,28	neutral	-2,63	deleterious	-4,23	medium_impact	3,19	neutral	0,83	damaging	0,18	deleterious	3,88	23,5	0,27	0,65	disease	0,76	disease	0,57	disease	0,55	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,64	0,58	0,9	17,26	17,02	N	0,33	N	0,81	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8552	8552	T	C	MI.1840	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	187	63	S	P	Tca/Cca	7,53	1	0	probably_damaging	0,94	neutral	0,18	neutral	1,31	deleterious	-4,21	deleterious	-3,19	medium_impact	3,09	neutral	0,99	damaging	0,27	deleterious	4,04	23,7	0,36812856	0,85	disease	0,57	neutral	0,35	disease	0,66	neutral	0,31	4	neutral	0,96	neutral	0,12	deleterious	1	deleterious	0,7	low_impact	-1,89	medium_impact	-0,08	medium_impact	1,55	0,29	0,85	NA	NA	P	0,68	P	0,71	disease_causing	0,99	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11747	11747	G	A	MI.18400	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	988	330	A	T	Gca/Aca	-0,2	0,54	0	probably_damaging	1	deleterious	0,04	neutral	4,38	deleterious	-3,02	deleterious	-3,79	medium_impact	3,04	neutral	0,64	damaging	0,11	deleterious	4,33	24	0,1	0,4	neutral	0,45	disease	0,77	disease	0,64	disease	0,56	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,77	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,88	0,73	0,85	47,28	9,3	N	0,27	N	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11747	11747	G	T	MI.18401	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	988	330	A	S	Gca/Tca	-0,2	0,54	0	probably_damaging	1	neutral	0,15	neutral	4,42	neutral	-2,1	deleterious	-2,83	medium_impact	2,58	neutral	0,62	damaging	0,16	deleterious	3,8	23,4	0,18	0,45	neutral	0,46	disease	0,76	disease	0,61	neutral	0,4	2	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,22	medium_impact	1,43	0,65	0,8	47,28	9,3	N	0,33	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11748	11748	C	T	MI.18402	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	989	330	A	V	gCa/gTa	6,01	1	0	probably_damaging	1	neutral	0,24	neutral	4,59	neutral	-0,95	deleterious	-3,8	low_impact	1,82	neutral	0,63	damaging	0,11	deleterious	4,52	24,3	0,11	0,4	neutral	0,38	disease	0,73	disease	0,69	disease	0,56	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	-0,08	medium_impact	0,68	0,68	0,85	47,28	9,3	P	0,58	P	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11748	11748	C	G	MI.18403	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	989	330	A	G	gCa/gGa	6,01	1	0	probably_damaging	1	deleterious	0,01	neutral	4,34	deleterious	-4	deleterious	-3,79	medium_impact	2,69	neutral	0,6	damaging	0,12	deleterious	3,96	23,6	0,09	0,35	neutral	0,23	disease	0,74	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,71	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,54	0,73	0,85	47,28	9,3	P	0,53	P	0,79	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11748	11748	C	A	MI.18404	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	989	330	A	E	gCa/gAa	6,01	1	0	probably_damaging	1	deleterious	0	neutral	4,34	deleterious	-5,51	deleterious	-4,74	high_impact	4,01	neutral	0,68	damaging	0,1	deleterious	4,63	24,5	0,02	0,35	neutral	0,35	disease	0,85	disease	0,77	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	2,84	0,43	0,8	47,28	9,3	P	0,59	P	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11750	11750	A	T	MI.18405	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	991	331	N	Y	Aac/Tac	-8,26	0	0	probably_damaging	1	deleterious	0,04	neutral	4,53	neutral	-1,86	deleterious	-7,6	medium_impact	3,06	damaging	0,52	damaging	0,09	deleterious	3,88	23,5	0,05	0,35	disease	0,78	disease	0,85	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,85	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,9	0,24	0,8	46,84	9,35	N	0,29	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11750	11750	A	G	MI.18406	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	991	331	N	D	Aac/Gac	-8,26	0	0	probably_damaging	1	deleterious	0,02	neutral	4,59	neutral	0,19	deleterious	-4,75	medium_impact	3,25	damaging	0,55	damaging	0,12	deleterious	3,98	23,6	0,28	0,45	disease	0,64	disease	0,75	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-3,54	medium_impact	-0,75	high_impact	2,09	0,28	0,8	46,84	9,35	N	0,32	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11750	11750	A	C	MI.18407	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	991	331	N	H	Aac/Cac	-8,26	0	0	probably_damaging	1	deleterious	0	neutral	4,54	neutral	-1,1	deleterious	-4,75	high_impact	3,64	damaging	0,54	damaging	0,13	deleterious	3,18	22,7	0,2	0,45	disease	0,79	disease	0,77	disease	0,78	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,48	0,25	0,8	46,84	9,35	N	0,34	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11751	11751	A	C	MI.18408	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	992	331	N	T	aAc/aCc	8,55	1	0	probably_damaging	1	neutral	0,09	neutral	4,59	neutral	-0,16	deleterious	-5,7	medium_impact	3,21	damaging	0,56	damaging	0,11	deleterious	3,4	23	0,15	0,4	disease	0,63	disease	0,79	disease	0,68	disease	0,67	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,36	high_impact	2,05	0,38	0,8	46,84	9,35	P	0,6	P	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11751	11751	A	T	MI.18409	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	992	331	N	I	aAc/aTc	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,58	neutral	-1,02	deleterious	-8,54	high_impact	4,11	damaging	0,51	damaging	0,12	deleterious	3,89	23,5	0,07	0,35	disease	0,83	disease	0,86	disease	0,68	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,94	0,16	0,8	46,84	9,35	P	0,64	P	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8552	8552	T	G	MI.1841	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	187	63	S	A	Tca/Gca	7,53	1	0	possibly_damaging	0,78	neutral	0,48	neutral	1,39	neutral	-2,12	neutral	-1,99	medium_impact	3,44	neutral	1	neutral	0,5	deleterious	3,85	23,4	0,5577664	0,85	neutral	0,36	neutral	0,14	disease	0,64	neutral	0,22	6	neutral	0,76	neutral	0,35	NA	0	deleterious	0,55	low_impact	-1,28	medium_impact	0,27	medium_impact	1,85	0,37	0,85	NA	NA	P	0,69	P	0,37	disease_causing	0,89	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11751	11751	A	G	MI.18410	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	992	331	N	S	aAc/aGc	8,55	1	0	probably_damaging	1	neutral	0,05	neutral	4,63	neutral	0,58	deleterious	-4,74	medium_impact	3	damaging	0,51	damaging	0,12	deleterious	3,08	22,5	0,29	0,45	disease	0,62	disease	0,78	disease	0,68	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,84	0,33	0,8	46,84	9,35	P	0,62	P	0,85	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11752	11752	C	A	MI.18411	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	993	331	N	K	aaC/aaA	8,55	1	0	probably_damaging	1	deleterious	0,01	neutral	4,64	neutral	0,32	deleterious	-5,7	high_impact	4,11	damaging	0,49	damaging	0,09	deleterious	4,55	24,3	0,18	0,45	disease	0,52	disease	0,79	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-3,54	medium_impact	-0,92	high_impact	2,94	0,39	0,8	46,84	9,35	P	0,62	P	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11752	11752	C	G	MI.18412	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	993	331	N	K	aaC/aaG	8,55	1	0	probably_damaging	1	deleterious	0,01	neutral	4,64	neutral	0,32	deleterious	-5,7	high_impact	4,11	damaging	0,49	damaging	0,09	deleterious	4,15	23,8	0,18	0,45	disease	0,52	disease	0,79	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-3,54	medium_impact	-0,92	high_impact	2,94	0,39	0,8	46,84	9,35	P	0,62	P	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11753	11753	T	C	MI.18413	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	994	332	S	P	Tca/Cca	-3,42	0	0	benign	0,08	neutral	0,06	neutral	4,46	deleterious	-3,68	deleterious	-2,83	medium_impact	2,73	neutral	0,6	neutral	0,42	deleterious	2,24	17,79	0,04	0,35	disease	0,61	disease	0,78	disease	0,66	disease	0,75	5	neutral	0,93	deleterious	0,49	neutral	-3	neutral	0,3	medium_impact	0,28	medium_impact	-0,47	medium_impact	1,58	0,24	0,8	21,13	15,25	N	0,34	N	0,95	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11753	11753	T	G	MI.18414	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	994	332	S	A	Tca/Gca	-3,42	0	0	possibly_damaging	0,52	neutral	0,16	neutral	4,57	neutral	-0,64	neutral	-1,55	low_impact	1,3	neutral	0,7	neutral	0,67	deleterious	2,01	16,28	0,3	0,45	neutral	0,36	neutral	0,26	disease	0,51	neutral	0,45	1	neutral	0,83	neutral	0,32	neutral	-3	neutral	0,2	medium_impact	-0,75	medium_impact	-0,2	medium_impact	0,16	0,41	0,8	21,13	15,25	N	0,43	N	0,44	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11753	11753	T	A	MI.18415	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	994	332	S	T	Tca/Aca	-3,42	0	0	possibly_damaging	0,77	neutral	0,99	neutral	4,56	neutral	-0,8	neutral	1,44	neutral_impact	-0,7	neutral	0,72	neutral	0,96	neutral	-0,39	0,41	0,27	0,45	neutral	0,28	neutral	0,04	neutral	0,13	neutral	0,21	6	neutral	0,77	deleterious	0,61	neutral	-3	neutral	0,23	low_impact	-1,21	medium_impact	1,32	low_impact	-1,82	0,59	0,8	21,13	15,25	N	0,4	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11754	11754	C	T	MI.18416	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	995	332	S	L	tCa/tTa	0,49	0,01	0	possibly_damaging	0,81	neutral	0,81	neutral	4,71	neutral	0,47	deleterious	-3,03	neutral_impact	0,6	neutral	0,71	neutral	0,72	deleterious	3,03	22,3	0,08	0,35	neutral	0,38	neutral	0,5	neutral	0,28	neutral	0,36	3	neutral	0,78	deleterious	0,5	neutral	-3	neutral	0,35	low_impact	-1,31	medium_impact	0,56	medium_impact	-0,53	0,34	0,8	21,13	15,25	N	0,33	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11754	11754	C	G	MI.18417	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	995	332	S	W	tCa/tGa	0,49	0,01	0	probably_damaging	0,99	neutral	0,05	neutral	4,45	deleterious	-4,42	deleterious	-4,04	medium_impact	2,17	neutral	0,69	neutral	0,45	deleterious	4,44	24,2	0,05	0,35	disease	0,88	disease	0,73	disease	0,61	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,8	low_impact	-2,59	medium_impact	-0,52	medium_impact	1,02	0,09	0,8	21,13	15,25	N	0,32	N	1	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11756	11756	A	T	MI.18418	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	997	333	N	Y	Aac/Tac	-14,94	0	0	probably_damaging	1	neutral	1	neutral	4,64	neutral	-0,78	deleterious	-6,76	medium_impact	2,31	neutral	0,77	neutral	0,38	deleterious	3,89	23,5	0,09	0,35	disease	0,58	disease	0,87	disease	0,59	disease	0,67	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,81	low_impact	-3,54	high_impact	1,88	medium_impact	1,16	0,3	0,8	46,84	9,38	N	0,19	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11756	11756	A	G	MI.18419	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	997	333	N	D	Aac/Gac	-14,94	0	0	probably_damaging	1	neutral	0,2	neutral	4,62	neutral	-1,26	deleterious	-4,18	high_impact	3,67	neutral	0,73	neutral	0,43	deleterious	3,98	23,6	0,34	0,5	neutral	0,44	disease	0,79	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	-0,14	high_impact	2,51	0,45	0,8	46,84	9,38	N	0,46	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8552	8552	T	A	MI.1842	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	187	63	S	T	Tca/Aca	7,53	1	0	possibly_damaging	0,85	neutral	1	neutral	1,36	neutral	-2,74	neutral	-1,99	medium_impact	3,44	neutral	1	neutral	0,43	deleterious	4,05	23,7	0,54043948	0,85	neutral	0,45	neutral	0,19	disease	0,59	neutral	0,21	6	neutral	0,85	deleterious	0,58	NA	0	deleterious	0,63	low_impact	-1,47	high_impact	1,98	medium_impact	1,85	0,45	0,85	NA	NA	P	0,56	P	0,46	disease_causing	0,97	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11756	11756	A	C	MI.18420	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	997	333	N	H	Aac/Cac	-14,94	0	0	probably_damaging	1	neutral	0,54	neutral	4,62	neutral	-1,04	deleterious	-4,28	medium_impact	3,33	neutral	0,75	neutral	0,3	deleterious	3,23	22,8	0,23	0,45	disease	0,62	disease	0,81	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	0,24	high_impact	2,17	0,37	0,8	46,84	9,38	N	0,25	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11757	11757	A	G	MI.18421	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	998	333	N	S	aAc/aGc	5,55	0,95	0	probably_damaging	1	neutral	0,41	neutral	4,69	neutral	0,49	deleterious	-3,83	low_impact	1,45	neutral	0,74	neutral	0,61	deleterious	1,94	15,84	0,39	0,5	neutral	0,32	disease	0,62	neutral	0,38	neutral	0,34	3	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	0,11	medium_impact	0,31	0,33	0,8	46,84	9,38	N	0,48	N	0,85	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11757	11757	A	T	MI.18422	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	998	333	N	I	aAc/aTc	5,55	0,95	0	probably_damaging	1	neutral	0,4	neutral	4,88	neutral	3,27	deleterious	-7,46	low_impact	1,48	neutral	0,73	neutral	0,5	deleterious	3,89	23,5	0,09	0,4	neutral	0,27	disease	0,89	neutral	0,46	neutral	0,38	2	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,75	low_impact	-3,54	medium_impact	0,1	medium_impact	0,34	0,27	0,8	46,84	9,38	N	0,45	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11757	11757	A	C	MI.18423	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	998	333	N	T	aAc/aCc	5,55	0,95	0	probably_damaging	1	neutral	0,4	neutral	4,67	neutral	0,63	deleterious	-4,48	low_impact	1,59	neutral	0,72	neutral	0,58	deleterious	2,26	17,9	0,19	0,45	neutral	0,3	disease	0,69	neutral	0,35	neutral	0,35	3	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,71	low_impact	-3,54	medium_impact	0,1	medium_impact	0,45	0,43	0,8	46,84	9,38	N	0,48	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11758	11758	C	A	MI.18424	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	999	333	N	K	aaC/aaA	2,1	0,91	0	probably_damaging	1	neutral	0,29	neutral	4,63	neutral	-0,76	deleterious	-4,96	high_impact	3,67	neutral	0,78	neutral	0,36	deleterious	4,56	24,4	0,24	0,45	neutral	0,42	disease	0,85	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	-0,02	high_impact	2,51	0,62	0,8	46,84	9,38	N	0,39	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11758	11758	C	G	MI.18425	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	999	333	N	K	aaC/aaG	2,1	0,91	0	probably_damaging	1	neutral	0,29	neutral	4,63	neutral	-0,76	deleterious	-4,96	high_impact	3,67	neutral	0,78	neutral	0,36	deleterious	4,14	23,8	0,24	0,45	neutral	0,42	disease	0,85	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	-0,02	high_impact	2,51	0,62	0,8	46,84	9,38	N	0,42	N	0,99	polymorphism	1	0,06	rs28735834	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11759	11759	T	C	MI.18426	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1000	334	Y	H	Tac/Cac	-1,12	0,01	0	probably_damaging	1	deleterious	0	neutral	4,43	deleterious	-3,83	deleterious	-4,74	high_impact	4,04	damaging	0,55	damaging	0,08	deleterious	3,81	23,4	0,12	0,4	disease	0,68	disease	0,87	disease	0,86	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	2,87	0,09	0,8	47,28	9,51	N	0,45	N	0,97	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11759	11759	T	A	MI.18427	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1000	334	Y	N	Tac/Aac	-1,12	0,01	0	probably_damaging	1	neutral	0,06	neutral	4,43	deleterious	-3,49	deleterious	-8,52	high_impact	4,04	damaging	0,52	damaging	0,1	deleterious	4,39	24,1	0,06	0,35	disease	0,62	disease	0,89	disease	0,8	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	-0,47	high_impact	2,87	0,03	0,8	47,28	9,51	N	0,49	N	1	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11759	11759	T	G	MI.18428	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1000	334	Y	D	Tac/Gac	-1,12	0,01	0	probably_damaging	1	deleterious	0	neutral	4,42	deleterious	-4,25	deleterious	-9,47	high_impact	4,04	neutral	0,61	damaging	0,11	deleterious	4,14	23,8	0,03	0,35	disease	0,69	disease	0,91	disease	0,86	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	2,87	0,04	0,8	47,28	9,51	N	0,49	N	0,99	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11760	11760	A	T	MI.18429	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1001	334	Y	F	tAc/tTc	5,78	1	0	probably_damaging	1	deleterious	0,02	neutral	4,48	neutral	-1,89	deleterious	-3,79	medium_impact	3,48	damaging	0,53	damaging	0,1	deleterious	3,58	23,2	0,17	0,45	neutral	0,29	disease	0,86	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,81	low_impact	-3,54	medium_impact	-0,75	high_impact	2,32	0,34	0,8	47,28	9,51	P	0,58	P	0,79	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8553	8553	C	T	MI.1843	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	188	63	S	L	tCa/tTa	7,53	1	0	possibly_damaging	0,9	neutral	0,33	neutral	1,38	neutral	-2,09	deleterious	-3,02	medium_impact	2,08	neutral	1	neutral	0,82	deleterious	3,77	23,4	0,36619744	0,85	neutral	0,31	neutral	0,3	neutral	0,48	neutral	0,21	6	neutral	0,91	neutral	0,22	NA	0	deleterious	0,66	low_impact	-1,66	medium_impact	0,12	medium_impact	0,69	0,72	0,85	NA	NA	P	0,7	P	0,55	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11760	11760	A	G	MI.18430	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1001	334	Y	C	tAc/tGc	5,78	1	0	probably_damaging	1	deleterious	0	neutral	4,45	neutral	-2,54	deleterious	-8,49	high_impact	3,69	damaging	0,56	damaging	0,09	deleterious	3,69	23,3	0,04	0,35	disease	0,7	disease	0,9	disease	0,83	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	2,53	0,03	0,8	47,28	9,51	P	0,66	P	1	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11760	11760	A	C	MI.18431	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1001	334	Y	S	tAc/tCc	5,78	1	0	probably_damaging	1	deleterious	0,02	neutral	4,5	neutral	-1,41	deleterious	-8,52	medium_impact	3,3	damaging	0,58	damaging	0,12	deleterious	3,84	23,4	0,06	0,35	neutral	0,33	disease	0,9	disease	0,8	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,54	medium_impact	-0,75	high_impact	2,14	0,06	0,8	47,28	9,51	P	0,6	P	0,95	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11762	11762	G	A	MI.18432	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1003	335	E	K	Gaa/Aaa	-6,19	0	0	possibly_damaging	0,89	neutral	0,08	neutral	4,6	neutral	-1,07	deleterious	-3,8	medium_impact	2,54	damaging	0,36	neutral	0,35	deleterious	4,65	24,5	0,07	0,35	disease	0,5	disease	0,92	disease	0,76	disease	0,74	5	neutral	0,97	neutral	0,1	NA	0	deleterious	0,87	low_impact	-1,57	medium_impact	-0,39	medium_impact	1,39	0,73	0,85	47,49	9,37	P	0,63	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11762	11762	G	C	MI.18433	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1003	335	E	Q	Gaa/Caa	-6,19	0	0	probably_damaging	0,95	deleterious	0,01	neutral	4,59	neutral	-1,08	deleterious	-2,85	medium_impact	3,29	damaging	0,4	neutral	0,5	deleterious	3,52	23,1	0,33	0,5	disease	0,58	disease	0,83	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,82	low_impact	-1,92	medium_impact	-0,92	high_impact	2,13	0,55	0,8	47,49	9,37	P	0,58	P	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11763	11763	A	G	MI.18434	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1004	335	E	G	gAa/gGa	9,01	1	0	probably_damaging	0,91	neutral	0,06	neutral	4,56	neutral	-2,46	deleterious	-6,64	medium_impact	3,29	damaging	0,43	neutral	0,59	deleterious	4,48	24,3	0,09	0,35	disease	0,65	disease	0,85	disease	0,75	disease	0,73	5	deleterious	0,98	neutral	0,08	deleterious	1	deleterious	0,83	low_impact	-1,66	medium_impact	-0,47	high_impact	2,13	0,16	0,8	47,49	9,37	P	0,76	P	0,53	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11763	11763	A	C	MI.18435	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1004	335	E	A	gAa/gCa	9,01	1	0	possibly_damaging	0,89	deleterious	0,01	neutral	4,58	neutral	-1,13	deleterious	-5,7	medium_impact	3,25	damaging	0,44	neutral	0,53	deleterious	3,85	23,4	0,1	0,4	neutral	0,43	disease	0,79	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,06	deleterious	4	deleterious	0,8	low_impact	-1,57	medium_impact	-0,92	high_impact	2,09	0,2	0,8	47,49	9,37	P	0,7	P	0,74	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11763	11763	A	T	MI.18436	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1004	335	E	V	gAa/gTa	9,01	1	0	probably_damaging	0,98	deleterious	0	neutral	4,53	neutral	-1,98	deleterious	-6,65	high_impact	4,09	damaging	0,37	neutral	0,44	deleterious	4,4	24,1	0,06	0,35	neutral	0,39	disease	0,9	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,31	low_impact	-1,48	high_impact	2,92	0,18	0,8	47,49	9,37	P	0,79	P	0,8	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11764	11764	A	T	MI.18437	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1005	335	E	D	gaA/gaT	8,55	1	0,01	benign	0,22	deleterious	0,02	neutral	4,63	neutral	-0,76	deleterious	-2,85	medium_impact	2,32	damaging	0,42	neutral	0,49	deleterious	3,93	23,5	0,36	0,5	disease	0,65	disease	0,81	disease	0,59	disease	0,66	3	neutral	0,98	neutral	0,4	deleterious	1	deleterious	0,82	medium_impact	-0,2	medium_impact	-0,75	medium_impact	1,17	0,61	0,8	47,49	9,37	P	0,73	P	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11764	11764	A	C	MI.18438	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1005	335	E	D	gaA/gaC	8,55	1	0,01	benign	0,22	deleterious	0,02	neutral	4,63	neutral	-0,76	deleterious	-2,85	medium_impact	2,32	damaging	0,42	neutral	0,49	deleterious	3,81	23,4	0,36	0,5	disease	0,65	disease	0,81	disease	0,59	disease	0,66	3	neutral	0,98	neutral	0,4	deleterious	1	deleterious	0,82	medium_impact	-0,2	medium_impact	-0,75	medium_impact	1,17	0,61	0,8	47,49	9,37	P	0,72	P	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11765	11765	C	T	MI.18439	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1006	336	R	C	Cgc/Tgc	0,03	0,91	0	probably_damaging	1	deleterious	0	neutral	4,41	deleterious	-5,33	deleterious	-7,53	medium_impact	3,2	damaging	0,51	damaging	0,19	deleterious	5,11	25,3	0,1	0,4	disease	0,85	disease	0,91	disease	0,78	disease	0,72	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	2,04	0,66	0,8	47,28	9,56	N	0,43	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8553	8553	C	G	MI.1844	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	188	63	S	W	tCa/tGa	7,53	1	0	probably_damaging	0,98	deleterious	0,02	neutral	1,29	deleterious	-6,27	deleterious	-4,32	medium_impact	3,44	neutral	1	neutral	0,38	deleterious	4,64	24,5	0,20969531	0,85	disease	0,89	neutral	0,37	disease	0,69	neutral	0,36	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-2,36	medium_impact	-0,66	medium_impact	1,85	0,24	0,85	NA	NA	P	0,66	P	0,82	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11765	11765	C	A	MI.18440	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1006	336	R	S	Cgc/Agc	0,03	0,91	0	probably_damaging	1	deleterious	0,03	neutral	4,51	neutral	-1,89	deleterious	-5,66	medium_impact	2,92	damaging	0,46	neutral	0,35	deleterious	4,82	24,8	0,08	0,35	disease	0,57	disease	0,9	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,87	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,76	0,26	0,8	47,28	9,56	N	0,43	N	0,81	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11765	11765	C	G	MI.18441	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1006	336	R	G	Cgc/Ggc	0,03	0,91	0	probably_damaging	1	deleterious	0,01	neutral	4,45	neutral	-2,3	deleterious	-6,59	high_impact	3,9	damaging	0,48	neutral	0,34	deleterious	4,31	24	0,07	0,35	disease	0,56	disease	0,87	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,54	medium_impact	-0,92	high_impact	2,73	0,26	0,8	47,28	9,56	P	0,48	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11766	11766	G	C	MI.18442	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1007	336	R	P	cGc/cCc	3,48	1	0	probably_damaging	1	deleterious	0	neutral	4,43	deleterious	-3,91	deleterious	-6,62	high_impact	4,45	damaging	0,48	damaging	0,23	deleterious	4,37	24,1	0,04	0,35	disease	0,82	disease	0,91	disease	0,77	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,54	low_impact	-1,48	high_impact	3,28	0,18	0,8	47,28	9,56	P	0,65	P	0,99	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11766	11766	G	T	MI.18443	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1007	336	R	L	cGc/cTc	3,48	1	0	probably_damaging	1	deleterious	0,04	neutral	4,43	deleterious	-3,05	deleterious	-6,62	medium_impact	3,12	damaging	0,51	neutral	0,29	deleterious	4,46	24,2	0,09	0,35	neutral	0,27	disease	0,94	disease	0,75	disease	0,79	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,82	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,96	0,03	0,8	47,28	9,56	P	0,53	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11766	11766	G	A	MI.18444	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1007	336	R	H	cGc/cAc	3,48	1	0	probably_damaging	1	deleterious	0,01	neutral	4,42	deleterious	-3,32	deleterious	-4,72	high_impact	3,9	damaging	0,46	damaging	0,17	deleterious	4,61	24,4	0,22	0,45	disease	0,8	disease	0,87	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-3,54	medium_impact	-0,92	high_impact	2,73	0,73	0,85	47,28	9,56	P	0,61	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11768	11768	A	G	MI.18445	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1009	337	T	A	Act/Gct	-20	0	0	possibly_damaging	0,7	neutral	0,19	neutral	4,61	neutral	-1,46	deleterious	-2,59	medium_impact	2,36	neutral	0,77	neutral	0,35	deleterious	3,57	23,1	0,31	0,45	neutral	0,4	disease	0,51	disease	0,6	disease	0,56	1	neutral	0,85	neutral	0,25	NA	0	deleterious	0,71	low_impact	-1,06	medium_impact	-0,15	medium_impact	1,21	0,24	0,8	11,76	13,38	N	0,35	N	0,27	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11768	11768	A	C	MI.18446	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1009	337	T	P	Act/Cct	-20	0	0	probably_damaging	0,98	neutral	0,08	neutral	4,55	deleterious	-4,33	deleterious	-4,01	high_impact	4,06	neutral	0,61	damaging	0,15	deleterious	3,65	23,2	0,03	0,35	disease	0,65	disease	0,82	disease	0,6	disease	0,67	3	deleterious	0,99	neutral	0,05	deleterious	2	deleterious	0,82	low_impact	-2,31	medium_impact	-0,39	high_impact	2,89	0,13	0,8	11,76	13,38	N	0,34	N	0,91	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11768	11768	A	T	MI.18447	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1009	337	T	S	Act/Tct	-20	0	0	possibly_damaging	0,88	neutral	0,63	neutral	4,7	neutral	-2	deleterious	-2,56	low_impact	1,75	neutral	0,71	neutral	0,29	deleterious	3,46	23	0,38	0,5	neutral	0,37	disease	0,55	neutral	0,33	neutral	0,38	3	neutral	0,86	neutral	0,38	neutral	-3	deleterious	0,73	low_impact	-1,53	medium_impact	0,33	medium_impact	0,61	0,28	0,8	11,76	13,38	N	0,28	N	0,32	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11769	11769	C	T	MI.18448	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1010	337	T	I	aCt/aTt	1,64	0	0	benign	0,08	neutral	0,33	neutral	4,61	neutral	-2,55	neutral	-1,34	low_impact	1,7	neutral	0,78	neutral	0,95	deleterious	2,3	18,14	0,16	0,45	neutral	0,44	disease	0,55	neutral	0,36	neutral	0,39	2	neutral	0,63	deleterious	0,63	neutral	-6	deleterious	0,73	medium_impact	0,28	medium_impact	0,03	medium_impact	0,56	0,36	0,8	11,76	13,38	N	0,41	N	0,05	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11769	11769	C	G	MI.18449	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1010	337	T	S	aCt/aGt	1,64	0	0	possibly_damaging	0,88	neutral	0,63	neutral	4,7	neutral	-2	deleterious	-2,56	low_impact	1,75	neutral	0,71	neutral	0,29	deleterious	3,63	23,2	0,38	0,5	neutral	0,37	disease	0,55	neutral	0,33	neutral	0,38	3	neutral	0,86	neutral	0,38	neutral	-3	deleterious	0,73	low_impact	-1,53	medium_impact	0,33	medium_impact	0,61	0,28	0,8	11,76	13,38	N	0,25	N	0,32	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8555	8555	T	G	MI.1845	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	190	64	L	V	Ttg/Gtg	-3,11	0	0	possibly_damaging	0,9	neutral	0,37	neutral	1,66	neutral	-2,2	neutral	-2,08	medium_impact	2,82	neutral	1	neutral	0,51	deleterious	2,52	19,6	0,752753	0,85	disease	0,55	neutral	0,06	disease	0,54	neutral	0,05	9	neutral	0,9	neutral	0,24	NA	0	deleterious	0,62	low_impact	-1,66	medium_impact	0,16	medium_impact	1,32	0,61	0,85	2,94	7,63	N	0,5	N	0,44	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11769	11769	C	A	MI.18450	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1010	337	T	N	aCt/aAt	1,64	0	0	probably_damaging	0,97	neutral	0,16	neutral	4,63	deleterious	-3,22	deleterious	-3,54	medium_impact	2,91	neutral	0,69	damaging	0,2	deleterious	3,7	23,3	0,31	0,45	neutral	0,22	disease	0,7	neutral	0,5	neutral	0,47	1	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,7	low_impact	-2,14	medium_impact	-0,2	medium_impact	1,75	0,31	0,8	11,76	13,38	N	0,37	N	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11771	11771	C	G	MI.18451	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1012	338	H	D	Cac/Gac	-7,57	0	0	probably_damaging	1	deleterious	0,04	neutral	4,6	neutral	-1,89	deleterious	-8,5	high_impact	3,74	neutral	0,67	damaging	0,11	deleterious	4	23,6	0,12	0,4	disease	0,61	disease	0,88	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,83	low_impact	-3,54	medium_impact	-0,57	high_impact	2,57	0,19	0,8	46,19	9,25	N	0,39	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11771	11771	C	T	MI.18452	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1012	338	H	Y	Cac/Tac	-7,57	0	0	probably_damaging	1	neutral	0,25	neutral	4,57	deleterious	-3,92	deleterious	-5,67	medium_impact	2,85	neutral	0,7	damaging	0,11	deleterious	3,89	23,5	0,26	0,45	disease	0,62	disease	0,86	disease	0,68	disease	0,64	3	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,07	medium_impact	1,69	0,23	0,8	46,19	9,25	N	0,25	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11771	11771	C	A	MI.18453	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1012	338	H	N	Cac/Aac	-7,57	0	0	probably_damaging	1	neutral	0,25	neutral	4,68	neutral	-1,94	deleterious	-6,6	low_impact	1,15	neutral	0,72	neutral	0,3	deleterious	4,05	23,7	0,54	0,6	neutral	0,38	disease	0,73	disease	0,53	neutral	0,44	1	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	-0,07	medium_impact	0,01	0,26	0,8	46,19	9,25	N	0,28	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11772	11772	A	T	MI.18454	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1013	338	H	L	cAc/cTc	4,17	0,99	0	probably_damaging	1	neutral	0,16	neutral	4,6	deleterious	-3,53	deleterious	-10,4	medium_impact	2,81	neutral	0,71	damaging	0,1	deleterious	3,89	23,5	0,09	0,35	neutral	0,3	disease	0,9	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,2	medium_impact	1,65	0,17	0,8	46,19	9,25	N	0,45	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11772	11772	A	C	MI.18455	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1013	338	H	P	cAc/cCc	4,17	0,99	0	probably_damaging	1	deleterious	0,04	neutral	4,58	deleterious	-4,24	deleterious	-9,45	high_impact	3,74	neutral	0,72	damaging	0,11	deleterious	3,35	22,9	0,05	0,35	disease	0,5	disease	0,92	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,85	low_impact	-3,54	medium_impact	-0,57	high_impact	2,57	0,18	0,8	46,19	9,25	P	0,56	P	0,95	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11772	11772	A	G	MI.18456	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1013	338	H	R	cAc/cGc	4,17	0,99	0	probably_damaging	1	neutral	0,09	neutral	4,65	neutral	-2,32	deleterious	-7,56	medium_impact	3,28	neutral	0,66	damaging	0,1	deleterious	3,11	22,5	0,32	0,5	disease	0,55	disease	0,85	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,83	low_impact	-3,54	medium_impact	-0,36	high_impact	2,12	0,33	0,8	46,19	9,25	P	0,5	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11773	11773	C	A	MI.18457	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1014	338	H	Q	caC/caA	6,7	1	0	probably_damaging	1	neutral	0,09	neutral	4,62	neutral	-2,51	deleterious	-7,56	medium_impact	2,52	neutral	0,7	damaging	0,11	deleterious	4,06	23,7	0,37	0,5	disease	0,54	disease	0,8	disease	0,65	disease	0,53	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,36	medium_impact	1,37	0,25	0,8	46,19	9,25	N	0,51	P	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11773	11773	C	G	MI.18458	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1014	338	H	Q	caC/caG	6,7	1	0	probably_damaging	1	neutral	0,09	neutral	4,62	neutral	-2,51	deleterious	-7,56	medium_impact	2,52	neutral	0,7	damaging	0,11	deleterious	3,68	23,3	0,37	0,5	disease	0,54	disease	0,8	disease	0,65	disease	0,53	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,36	medium_impact	1,37	0,25	0,8	46,19	9,25	N	0,51	P	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11774	11774	A	T	MI.18459	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1015	339	S	C	Agt/Tgt	-1,12	0,02	0	probably_damaging	0,99	deleterious	0	neutral	4,44	deleterious	-4,54	deleterious	-4,68	medium_impact	3,42	neutral	0,63	damaging	0,1	deleterious	3,37	22,9	0,16	0,45	disease	0,89	disease	0,81	disease	0,57	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,81	low_impact	-2,59	low_impact	-1,48	high_impact	2,26	0,15	0,8	45,32	9,05	N	0,28	N	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8555	8555	T	A	MI.1846	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	190	64	L	M	Ttg/Atg	-3,11	0	0	probably_damaging	0,98	neutral	0,1	neutral	1,61	deleterious	-3,63	neutral	-1,2	low_impact	1,12	neutral	0,99	neutral	0,63	deleterious	2,7	20,8	0,54328946	0,85	disease	0,63	neutral	0,06	neutral	0,35	neutral	0,05	9	deleterious	0,99	neutral	0,06	neutral	-2	deleterious	0,67	low_impact	-2,36	medium_impact	-0,25	medium_impact	-0,14	0,52	0,85	2,94	7,63	P	0,59	P	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11774	11774	A	G	MI.18460	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1015	339	S	G	Agt/Ggt	-1,12	0,02	0	possibly_damaging	0,73	deleterious	0	neutral	4,47	neutral	-1,7	deleterious	-3,69	high_impact	4,12	neutral	0,69	damaging	0,14	deleterious	3,46	23	0,39	0,5	disease	0,58	disease	0,7	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,14	deleterious	5	deleterious	0,74	low_impact	-1,12	low_impact	-1,48	high_impact	2,95	0,36	0,8	45,32	9,05	N	0,41	N	0,87	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11774	11774	A	C	MI.18461	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1015	339	S	R	Agt/Cgt	-1,12	0,02	0	probably_damaging	0,96	deleterious	0	neutral	4,49	neutral	-1,99	deleterious	-4,59	high_impact	3,77	neutral	0,63	damaging	0,08	deleterious	3,75	23,3	0,1	0,4	disease	0,54	disease	0,85	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,81	low_impact	-2,01	low_impact	-1,48	high_impact	2,6	0,33	0,8	45,32	9,05	N	0,36	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11775	11775	G	A	MI.18462	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1016	339	S	N	aGt/aAt	8,55	1	0	benign	0,17	deleterious	0	neutral	4,5	neutral	-1,75	deleterious	-2,57	medium_impact	3,02	neutral	0,71	neutral	0,28	deleterious	2,56	19,82	0,64	0,7	neutral	0,28	disease	0,73	neutral	0,43	neutral	0,36	3	deleterious	1	neutral	0,42	deleterious	1	deleterious	0,72	medium_impact	-0,07	low_impact	-1,48	medium_impact	1,86	0,53	0,8	45,32	9,05	P	0,58	P	0,91	polymorphism	1	0,1	.	.	.	.	.	.	COSM1132243	.	.	.	.	.	.	.	.
chrM	11775	11775	G	T	MI.18463	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1016	339	S	I	aGt/aTt	8,55	1	0	probably_damaging	0,98	deleterious	0	neutral	4,49	deleterious	-3,11	deleterious	-5,59	high_impact	4,12	neutral	0,62	damaging	0,11	deleterious	4,25	23,9	0,13	0,4	disease	0,74	disease	0,9	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,31	low_impact	-1,48	high_impact	2,95	0,23	0,8	45,32	9,05	P	0,6	P	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11775	11775	G	C	MI.18464	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1016	339	S	T	aGt/aCt	8,55	1	0	possibly_damaging	0,86	neutral	0,39	neutral	4,63	neutral	0,91	deleterious	-2,7	neutral_impact	0,36	neutral	0,71	neutral	0,32	deleterious	3,48	23,1	0,41	0,5	disease	0,53	neutral	0,38	neutral	0,27	neutral	0,38	2	neutral	0,86	neutral	0,27	neutral	-3	deleterious	0,72	low_impact	-1,46	medium_impact	0,09	medium_impact	-0,77	0,39	0,8	45,32	9,05	P	0,56	P	0,73	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11777	11777	C	G	MI.18465	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1018	340	R	G	Cgc/Ggc	0,49	0,99	0	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-3,83	deleterious	-6,64	high_impact	3,92	damaging	0,41	neutral	0,31	deleterious	4,32	24	0,06	0,35	disease	0,6	disease	0,83	disease	0,8	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	2,75	0,27	0,8	46,62	9,41	P	0,84	P	0,98	disease_causing_automatic	0	0,23	rs28384199	Pathogenic|Pathogenic	Mitochondrial_complex_I_deficiency|Leigh_syndrome	RCV000010357.5|RCV000144013.2	MedGen:OMIM|MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	11777	11777	C	T	MI.18466	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1018	340	R	C	Cgc/Tgc	0,49	0,99	0	probably_damaging	1	deleterious	0	neutral	4,42	deleterious	-6,6	deleterious	-7,59	high_impact	4,61	damaging	0,42	damaging	0,14	deleterious	5,19	25,5	0,07	0,35	disease	0,59	disease	0,89	disease	0,83	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,44	0,77	0,85	46,62	9,41	P	0,71	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11777	11777	C	A	MI.18467	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1018	340	R	S	Cgc/Agc	0,49	0,99	0	probably_damaging	1	deleterious	0	neutral	4,52	neutral	-2,45	deleterious	-5,69	high_impact	4,05	damaging	0,44	neutral	0,32	deleterious	4,69	24,6	0,06	0,35	neutral	0,43	disease	0,89	disease	0,79	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	2,88	0,27	0,8	46,62	9,41	P	0,83	P	0,81	disease_causing_automatic	0	0,21	rs28384199	Pathogenic|Pathogenic	Mitochondrial_complex_I_deficiency|Leigh_syndrome	RCV000010357.5|RCV000144013.2	MedGen:OMIM|MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	C11777A	Leigh Disease	-	+	Cfrm	10
chrM	11778	11778	G	T	MI.18468	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1019	340	R	L	cGc/cTc	4,4	1	0,08	probably_damaging	1	deleterious	0	neutral	4,45	deleterious	-3,21	deleterious	-6,64	high_impact	3,56	damaging	0,39	damaging	0,26	deleterious	4,46	24,2	0,06	0,35	neutral	0,5	disease	0,92	disease	0,8	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	2,4	0,02	0,8	46,62	9,41	P	0,81	P	1	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11778	11778	G	C	MI.18469	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1019	340	R	P	cGc/cCc	4,4	1	0,08	probably_damaging	1	deleterious	0	neutral	4,44	deleterious	-4,4	deleterious	-6,64	high_impact	4,61	damaging	0,4	damaging	0,2	deleterious	4,35	24,1	0,03	0,35	neutral	0,28	disease	0,91	disease	0,87	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,44	0,13	0,8	46,62	9,41	P	0,76	P	0,99	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8556	8556	T	C	MI.1847	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	191	64	L	S	tTg/tCg	-0,33	0	0	probably_damaging	0,96	neutral	0,13	neutral	1,71	neutral	-2,01	deleterious	-3,73	low_impact	1,29	neutral	1	neutral	0,85	deleterious	4,02	23,6	0,80602268	0,9	disease	0,83	neutral	0,16	neutral	0,32	neutral	0,12	8	deleterious	0,98	neutral	0,09	neutral	-2	deleterious	0,73	low_impact	-2,07	medium_impact	-0,18	medium_impact	0,01	0,45	0,85	2,94	7,63	P	0,56	P	0,4	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11778	11778	G	A	MI.18470	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1019	340	R	H	cGc/cAc	4,4	1	0,08	probably_damaging	1	deleterious	0	neutral	4,44	deleterious	-3,75	deleterious	-4,74	high_impact	4,61	damaging	0,18	damaging	0,13	deleterious	4,56	24,4	0,21	0,45	disease	0,63	disease	0,87	disease	0,8	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,44	0,77	0,85	46,62	9,41	P	0,97	P	1	disease_causing_automatic	0	0,24	rs199476112	Pathogenic|Pathogenic	Leber's_optic_atrophy|not_provided	RCV000010354.2|RCV000224219.1	MedGen:OMIM:SNOMED_CT|MedGen	.	.	.	.	G11778A	LHON/Progressive Dystonia	+	+	Cfrm	258
chrM	11780	11780	A	T	MI.18471	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1021	341	I	F	Atc/Ttc	-4,12	0	0	possibly_damaging	0,85	deleterious	0,02	neutral	4,62	neutral	-1,29	neutral	-1,06	medium_impact	2,65	neutral	0,71	neutral	0,49	deleterious	2,35	18,48	0,15	0,4	disease	0,56	disease	0,61	disease	0,52	disease	0,59	2	deleterious	0,99	neutral	0,09	deleterious	4	deleterious	0,56	low_impact	-1,43	medium_impact	-0,75	medium_impact	1,5	0,42	0,8	19,39	24,04	N	0,42	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11780	11780	A	G	MI.18472	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1021	341	I	V	Atc/Gtc	-4,12	0	0	benign	0,23	neutral	0,06	neutral	4,64	neutral	0,2	neutral	0,87	low_impact	1,68	neutral	0,75	neutral	0,76	neutral	1,35	12,55	0,52	0,6	neutral	0,34	neutral	0,27	neutral	0,39	neutral	0,43	1	neutral	0,93	neutral	0,42	neutral	-6	neutral	0,17	medium_impact	-0,23	medium_impact	-0,47	medium_impact	0,54	0,53	0,8	19,39	24,04	N	0,5	N	0,49	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11780	11780	A	C	MI.18473	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1021	341	I	L	Atc/Ctc	-4,12	0	0	benign	0,23	neutral	0,29	neutral	4,72	neutral	0,97	neutral	-0,08	neutral_impact	0,66	neutral	0,76	neutral	0,57	deleterious	2,07	16,68	0,34	0,5	neutral	0,33	neutral	0,39	neutral	0,47	neutral	0,45	1	neutral	0,65	deleterious	0,53	neutral	-6	neutral	0,21	medium_impact	-0,23	medium_impact	-0,02	medium_impact	-0,47	0,4	0,8	19,39	24,04	N	0,37	N	0,49	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11781	11781	T	C	MI.18474	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1022	341	I	T	aTc/aCc	5,55	0,99	0	benign	0,01	neutral	1	neutral	4,74	neutral	0,4	neutral	5,17	neutral_impact	-1,11	neutral	0,71	neutral	0,86	neutral	-1,1	0,01	0,21	0,45	neutral	0,26	neutral	0,09	neutral	0,17	neutral	0,28	4	neutral	0,01	deleterious	1	neutral	-6	neutral	0,12	medium_impact	1,16	high_impact	1,88	low_impact	-2,22	0,18	0,8	19,39	24,04	P	0,54	P	0,08	polymorphism	1	0,01	.	.	.	.	.	pancreatic cancer cell line, MNGIE fibroblasts	.	.	.	.	.	.	.	.	.
chrM	11781	11781	T	G	MI.18475	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1022	341	I	S	aTc/aGc	5,55	0,99	0	benign	0,32	neutral	1	neutral	4,75	neutral	1,09	neutral	1,57	neutral_impact	-0,12	neutral	0,76	neutral	0,76	deleterious	2,55	19,81	0,09	0,4	neutral	0,47	neutral	0,45	neutral	0,29	neutral	0,46	1	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,28	medium_impact	-0,41	high_impact	1,88	low_impact	-1,25	0,16	0,8	19,39	24,04	N	0,44	N	0,56	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11781	11781	T	A	MI.18476	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1022	341	I	N	aTc/aAc	5,55	0,99	0	possibly_damaging	0,57	neutral	0,26	neutral	4,76	neutral	1,09	neutral	0,6	neutral_impact	0,72	neutral	0,76	neutral	0,51	deleterious	2,78	21,3	0,22	0,45	neutral	0,28	disease	0,73	neutral	0,27	neutral	0,44	1	neutral	0,74	neutral	0,35	neutral	-3	deleterious	0,49	medium_impact	-0,83	medium_impact	-0,05	medium_impact	-0,41	0,08	0,8	19,39	24,04	P	0,56	P	0,56	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11782	11782	C	A	MI.18477	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1023	341	I	M	atC/atA	2,79	0,98	0	possibly_damaging	0,89	neutral	0,11	neutral	4,64	neutral	-0,7	neutral	-0,11	low_impact	1,26	neutral	0,75	neutral	0,69	deleterious	3,69	23,3	0,47	0,55	disease	0,53	neutral	0,4	neutral	0,33	neutral	0,4	2	neutral	0,96	neutral	0,11	neutral	-3	deleterious	0,61	low_impact	-1,57	medium_impact	-0,31	medium_impact	0,12	0,48	0,8	19,39	24,04	P	0,62	P	0,63	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11782	11782	C	G	MI.18478	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1023	341	I	M	atC/atG	2,79	0,98	0	possibly_damaging	0,89	neutral	0,11	neutral	4,64	neutral	-0,7	neutral	-0,11	low_impact	1,26	neutral	0,75	neutral	0,69	deleterious	3,16	22,6	0,47	0,55	disease	0,53	neutral	0,4	neutral	0,33	neutral	0,4	2	neutral	0,96	neutral	0,11	neutral	-3	deleterious	0,61	low_impact	-1,57	medium_impact	-0,31	medium_impact	0,12	0,48	0,8	19,39	24,04	P	0,62	P	0,63	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11783	11783	A	T	MI.18479	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1024	342	M	L	Ata/Tta	-8,95	0	0	probably_damaging	0,98	neutral	1	neutral	4,89	neutral	0,53	neutral	-2,1	neutral_impact	-0,34	neutral	0,71	neutral	0,66	deleterious	1,88	15,48	0,2	0,45	neutral	0,25	neutral	0,23	neutral	0,28	neutral	0,44	1	deleterious	0,98	deleterious	0,51	neutral	-2	deleterious	0,53	low_impact	-2,31	high_impact	1,88	low_impact	-1,46	0,39	0,8	25,93	8,72	N	0,26	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8556	8556	T	G	MI.1848	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	191	64	L	W	tTg/tGg	-0,33	0	0	probably_damaging	0,99	neutral	0,13	neutral	1,57	deleterious	-5,93	deleterious	-4,12	medium_impact	2,82	neutral	1	neutral	0,37	deleterious	4,01	23,6	0,44486802	0,85	disease	0,92	neutral	0,14	disease	0,67	neutral	0,23	5	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,74	low_impact	-2,65	medium_impact	-0,18	medium_impact	1,32	0,45	0,85	2,94	7,63	N	0,55	P	0,81	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11783	11783	A	C	MI.18480	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1024	342	M	L	Ata/Cta	-8,95	0	0	probably_damaging	0,98	neutral	1	neutral	4,89	neutral	0,53	neutral	-2,1	neutral_impact	-0,34	neutral	0,71	neutral	0,66	deleterious	1,81	15,07	0,2	0,45	neutral	0,25	neutral	0,23	neutral	0,28	neutral	0,44	1	deleterious	0,98	deleterious	0,51	neutral	-2	deleterious	0,53	low_impact	-2,31	high_impact	1,88	low_impact	-1,46	0,39	0,8	25,93	8,72	N	0,26	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11783	11783	A	G	MI.18481	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1024	342	M	V	Ata/Gta	-8,95	0	0	probably_damaging	0,99	neutral	0,12	neutral	4,64	neutral	-0,99	deleterious	-3,35	low_impact	1,88	neutral	0,71	damaging	0,12	deleterious	2,85	21,6	0,2	0,45	neutral	0,39	disease	0,73	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,66	low_impact	-2,59	medium_impact	-0,28	medium_impact	0,73	0,42	0,8	25,93	8,72	N	0,27	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11784	11784	T	C	MI.18482	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1025	342	M	T	aTa/aCa	0,95	0,3	0	probably_damaging	1	deleterious	0,03	neutral	4,61	neutral	-2,03	deleterious	-5,25	medium_impact	2,83	neutral	0,68	damaging	0,11	deleterious	3,09	22,5	0,05	0,35	neutral	0,45	disease	0,78	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,77	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,67	0,13	0,8	25,93	8,72	N	0,29	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11784	11784	T	A	MI.18483	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1025	342	M	K	aTa/aAa	0,95	0,3	0	probably_damaging	1	deleterious	0	neutral	4,53	deleterious	-3,15	deleterious	-5,4	high_impact	3,63	neutral	0,66	damaging	0,09	deleterious	4,1	23,7	0,02	0,35	neutral	0,46	disease	0,86	disease	0,73	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	2,47	0,18	0,8	25,93	8,72	N	0,35	N	1	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11785	11785	A	C	MI.18484	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1026	342	M	I	atA/atC	7,4	0,97	0	probably_damaging	0,99	neutral	0,33	neutral	4,85	neutral	0,83	deleterious	-3,2	low_impact	1,23	neutral	0,71	damaging	0,2	deleterious	3,52	23,1	0,21	0,45	neutral	0,44	disease	0,7	neutral	0,42	neutral	0,36	3	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,72	low_impact	-2,59	medium_impact	0,03	medium_impact	0,09	0,5	0,8	25,93	8,72	N	0,51	P	0,95	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11785	11785	A	T	MI.18485	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1026	342	M	I	atA/atT	7,4	0,97	0	probably_damaging	0,99	neutral	0,33	neutral	4,85	neutral	0,83	deleterious	-3,2	low_impact	1,23	neutral	0,71	damaging	0,2	deleterious	3,57	23,2	0,21	0,45	neutral	0,44	disease	0,7	neutral	0,42	neutral	0,36	3	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,72	low_impact	-2,59	medium_impact	0,03	medium_impact	0,09	0,5	0,8	25,93	8,72	N	0,53	P	0,95	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11786	11786	A	T	MI.18486	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1027	343	I	F	Atc/Ttc	0,26	0,01	0	benign	0,37	neutral	0,41	neutral	4,66	neutral	-1,79	deleterious	-2,62	low_impact	1,18	neutral	0,8	neutral	0,72	deleterious	3,87	23,5	0,13	0,4	disease	0,71	neutral	0,48	neutral	0,24	disease	0,56	1	neutral	0,52	deleterious	0,52	neutral	-6	deleterious	0,76	medium_impact	-0,5	medium_impact	0,11	medium_impact	0,04	0,4	0,8	27,45	26,1	N	0,31	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11786	11786	A	G	MI.18487	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1027	343	I	V	Atc/Gtc	0,26	0,01	0	benign	0,13	neutral	0,23	neutral	4,68	neutral	-0,73	neutral	-0,7	low_impact	1,05	neutral	0,75	neutral	0,84	deleterious	1,8	15	0,43	0,55	disease	0,51	neutral	0,17	neutral	0,22	neutral	0,27	5	neutral	0,73	deleterious	0,55	neutral	-6	deleterious	0,62	medium_impact	0,06	medium_impact	-0,09	medium_impact	-0,09	0,43	0,8	27,45	26,1	N	0,51	P	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11786	11786	A	C	MI.18488	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1027	343	I	L	Atc/Ctc	0,26	0,01	0	benign	0,01	neutral	1	neutral	4,7	neutral	-0,81	neutral	-0,25	neutral_impact	0,21	neutral	0,75	neutral	0,95	neutral	1,47	13,16	0,29	0,45	neutral	0,45	neutral	0,13	neutral	0,12	neutral	0,27	5	neutral	0,01	deleterious	1	neutral	-6	deleterious	0,62	medium_impact	1,16	high_impact	1,88	medium_impact	-0,92	0,27	0,8	27,45	26,1	N	0,36	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11787	11787	T	G	MI.18489	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1028	343	I	S	aTc/aGc	-2,73	0	0	benign	0,27	neutral	0,1	neutral	4,67	neutral	0,92	deleterious	-4,33	low_impact	1,8	neutral	0,74	neutral	0,42	deleterious	4,43	24,2	0,11	0,4	disease	0,63	disease	0,65	neutral	0,44	neutral	0,46	1	neutral	0,88	neutral	0,42	neutral	-6	deleterious	0,78	medium_impact	-0,31	medium_impact	-0,33	medium_impact	0,66	0,16	0,8	27,45	26,1	N	0,34	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8557	8557	G	C	MI.1849	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	192	64	L	F	ttG/ttC	-0,8	0	0,02	probably_damaging	0,96	neutral	0,24	neutral	1,61	deleterious	-3,53	deleterious	-2,82	medium_impact	2,82	neutral	0,98	neutral	0,47	deleterious	3,2	22,7	0,76071314	0,85	disease	0,66	neutral	0,08	disease	0,65	neutral	0,15	7	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,67	low_impact	-2,07	medium_impact	0,01	medium_impact	1,32	0,44	0,85	2,94	7,63	P	0,53	P	0,57	polymorphism	1	0,17	rs386829040	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11787	11787	T	C	MI.18490	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1028	343	I	T	aTc/aCc	-2,73	0	0	benign	0,27	deleterious	0,04	neutral	4,69	neutral	0,25	deleterious	-3,39	low_impact	1,02	neutral	0,8	neutral	0,7	deleterious	3,57	23,1	0,17	0,45	neutral	0,35	neutral	0,42	neutral	0,26	neutral	0,48	0	neutral	0,95	neutral	0,39	neutral	-2	deleterious	0,68	medium_impact	-0,31	medium_impact	-0,57	medium_impact	-0,12	0,2	0,8	27,45	26,1	N	0,38	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11787	11787	T	A	MI.18491	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1028	343	I	N	aTc/aAc	-2,73	0	0	possibly_damaging	0,73	deleterious	0,02	neutral	4,63	neutral	0,25	deleterious	-5,29	medium_impact	2	neutral	0,73	neutral	0,42	deleterious	4,77	24,7	0,19	0,45	disease	0,82	disease	0,7	disease	0,51	disease	0,61	2	deleterious	0,98	neutral	0,15	deleterious	4	deleterious	0,82	low_impact	-1,12	medium_impact	-0,75	medium_impact	0,85	0,13	0,8	27,45	26,1	N	0,29	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11788	11788	C	G	MI.18492	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1029	343	I	M	atC/atG	7,4	0,95	0	benign	0,03	neutral	0,24	neutral	4,63	neutral	-1,9	neutral	-1,04	neutral_impact	0,69	neutral	0,75	neutral	0,91	deleterious	2,26	17,93	0,42	0,55	disease	0,56	neutral	0,3	neutral	0,18	disease	0,59	2	neutral	0,75	deleterious	0,61	neutral	-6	deleterious	0,71	medium_impact	0,7	medium_impact	-0,08	medium_impact	-0,44	0,39	0,8	27,45	26,1	P	0,58	P	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11788	11788	C	A	MI.18493	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1029	343	I	M	atC/atA	7,4	0,95	0	benign	0,03	neutral	0,24	neutral	4,63	neutral	-1,9	neutral	-1,04	neutral_impact	0,69	neutral	0,75	neutral	0,91	deleterious	2,73	21	0,42	0,55	disease	0,56	neutral	0,3	neutral	0,18	disease	0,59	2	neutral	0,75	deleterious	0,61	neutral	-6	deleterious	0,71	medium_impact	0,7	medium_impact	-0,08	medium_impact	-0,44	0,39	0,8	27,45	26,1	P	0,58	P	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11789	11789	C	G	MI.18494	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1030	344	L	V	Ctc/Gtc	-20	0	0	possibly_damaging	0,74	neutral	0,19	neutral	4,61	neutral	-1,77	deleterious	-2,66	medium_impact	2,09	neutral	0,72	neutral	0,51	deleterious	3,57	23,2	0,43	0,55	neutral	0,38	neutral	0,48	neutral	0,41	neutral	0,45	1	neutral	0,86	neutral	0,23	NA	0	deleterious	0,72	low_impact	-1,14	medium_impact	-0,15	medium_impact	0,94	0,23	0,8	24,4	23,16	N	0,43	N	0,46	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11789	11789	C	T	MI.18495	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1030	344	L	F	Ctc/Ttc	-20	0	0	benign	0,12	neutral	0,13	neutral	4,57	neutral	-2,04	deleterious	-3,14	medium_impact	2,28	neutral	0,69	neutral	0,65	deleterious	4,08	23,7	0,41	0,5	disease	0,62	disease	0,53	neutral	0,44	neutral	0,44	1	neutral	0,85	deleterious	0,51	neutral	-3	deleterious	0,77	medium_impact	0,1	medium_impact	-0,26	medium_impact	1,13	0,29	0,8	24,4	23,16	N	0,42	N	0,73	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11789	11789	C	A	MI.18496	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1030	344	L	I	Ctc/Atc	-20	0	0	possibly_damaging	0,74	neutral	0,39	neutral	4,67	neutral	-2,2	neutral	-1,74	low_impact	1,68	neutral	0,79	neutral	0,62	deleterious	4,21	23,9	0,45	0,55	neutral	0,4	neutral	0,31	neutral	0,2	neutral	0,45	1	neutral	0,76	neutral	0,33	neutral	-3	deleterious	0,71	low_impact	-1,14	medium_impact	0,09	medium_impact	0,54	0,17	0,8	24,4	23,16	N	0,41	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11790	11790	T	G	MI.18497	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1031	344	L	R	cTc/cGc	-1,58	0	0	probably_damaging	0,97	deleterious	0,01	neutral	4,61	neutral	0,32	deleterious	-5,42	medium_impact	3,17	neutral	0,63	neutral	0,4	deleterious	4,34	24	0,1	0,4	disease	0,63	disease	0,81	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,83	low_impact	-2,14	medium_impact	-0,92	high_impact	2,01	0,15	0,8	24,4	23,16	N	0,33	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11790	11790	T	C	MI.18498	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1031	344	L	P	cTc/cCc	-1,58	0	0	probably_damaging	0,98	deleterious	0	neutral	4,56	neutral	-2,61	deleterious	-6,37	high_impact	3,73	neutral	0,62	neutral	0,44	deleterious	4,02	23,6	0,05	0,35	neutral	0,24	disease	0,81	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-2,31	low_impact	-1,48	high_impact	2,56	0,13	0,8	24,4	23,16	N	0,38	N	0,87	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11790	11790	T	A	MI.18499	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1031	344	L	H	cTc/cAc	-1,58	0	0	probably_damaging	0,98	deleterious	0,03	neutral	4,58	neutral	-1,9	deleterious	-6,19	medium_impact	3,27	neutral	0,72	neutral	0,43	deleterious	4,26	23,9	0,12	0,4	disease	0,74	disease	0,77	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,82	low_impact	-2,31	medium_impact	-0,64	high_impact	2,11	0,07	0,8	24,4	23,16	N	0,34	N	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8612	8612	T	C	MI.185	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	86	29	L	P	cTa/cCa	-2,42	0	0	probably_damaging	1	neutral	0,05	neutral	4,26	deleterious	-3,7	deleterious	-4,91	medium_impact	3,19	neutral	0,75	damaging	0,15	deleterious	3,62	23,2	0,21	0,65	disease	0,81	disease	0,78	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	-0,43	medium_impact	1,64	0,55	0,9	17,26	17,02	N	0,31	N	0,91	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8557	8557	G	T	MI.1850	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	192	64	L	F	ttG/ttT	-0,8	0	0,02	probably_damaging	0,96	neutral	0,24	neutral	1,61	deleterious	-3,53	deleterious	-2,82	medium_impact	2,82	neutral	0,98	neutral	0,47	deleterious	2,73	21	0,76071314	0,85	disease	0,66	neutral	0,08	disease	0,65	neutral	0,15	7	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,67	low_impact	-2,07	medium_impact	0,01	medium_impact	1,32	0,44	0,85	2,94	7,63	P	0,53	P	0,57	polymorphism	1	0,17	rs386829040	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11792	11792	T	A	MI.18500	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1033	345	S	T	Tct/Act	-2,04	0	0	benign	0,04	neutral	0,41	neutral	4,69	neutral	-0,21	neutral	-0,1	neutral_impact	-1	neutral	0,72	neutral	0,95	deleterious	2,53	19,65	0,3	0,45	neutral	0,39	neutral	0,09	neutral	0,13	neutral	0,26	5	neutral	0,56	deleterious	0,69	neutral	-6	deleterious	0,67	medium_impact	0,58	medium_impact	0,11	low_impact	-2,12	0,49	0,8	25,93	33,18	N	0,52	P	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11792	11792	T	G	MI.18501	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1033	345	S	A	Tct/Gct	-2,04	0	0	benign	0,01	neutral	0,55	neutral	4,67	neutral	0,44	neutral	1,77	neutral_impact	-0,59	neutral	0,66	neutral	0,92	neutral	1,09	11,14	0,31	0,45	neutral	0,27	neutral	0,05	neutral	0,14	neutral	0,22	6	neutral	0,43	deleterious	0,77	neutral	-6	deleterious	0,65	medium_impact	1,16	medium_impact	0,25	low_impact	-1,71	0,42	0,8	25,93	33,18	N	0,45	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11792	11792	T	C	MI.18502	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1033	345	S	P	Tct/Cct	-2,04	0	0	benign	0,03	neutral	0,2	neutral	4,61	neutral	-1,63	neutral	-1,95	medium_impact	2,19	neutral	0,71	neutral	0,46	deleterious	4,09	23,7	0,11	0,4	disease	0,74	disease	0,79	disease	0,65	disease	0,75	5	neutral	0,79	deleterious	0,59	neutral	-3	deleterious	0,87	medium_impact	0,7	medium_impact	-0,14	medium_impact	1,04	0,33	0,8	25,93	33,18	N	0,32	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11793	11793	C	T	MI.18503	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1034	345	S	F	tCt/tTt	0,49	0	0	possibly_damaging	0,9	neutral	0,69	neutral	4,67	neutral	1,15	deleterious	-2,7	neutral_impact	0,66	neutral	0,66	neutral	0,57	deleterious	4,32	24	0,08	0,35	neutral	0,41	disease	0,56	disease	0,56	disease	0,68	4	neutral	0,89	neutral	0,4	neutral	-3	deleterious	0,74	low_impact	-1,61	medium_impact	0,4	medium_impact	-0,47	0,06	0,8	25,93	33,18	N	0,28	N	0,93	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11793	11793	C	G	MI.18504	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1034	345	S	C	tCt/tGt	0,49	0	0	probably_damaging	0,93	neutral	0,18	neutral	4,61	neutral	-1,82	neutral	-1,19	low_impact	0,8	neutral	0,65	neutral	0,42	deleterious	3,72	23,3	0,1	0,4	disease	0,76	disease	0,52	neutral	0,49	disease	0,51	0	neutral	0,96	neutral	0,13	neutral	-2	deleterious	0,76	low_impact	-1,77	medium_impact	-0,17	medium_impact	-0,33	0,24	0,8	25,93	33,18	N	0,39	N	0,58	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11793	11793	C	A	MI.18505	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1034	345	S	Y	tCt/tAt	0,49	0	0	probably_damaging	0,93	neutral	1	neutral	4,87	neutral	1,61	deleterious	-2,74	neutral_impact	0,22	neutral	0,72	neutral	0,62	deleterious	4,11	23,7	0,09	0,35	disease	0,65	disease	0,54	disease	0,56	disease	0,68	4	neutral	0,93	deleterious	0,54	neutral	-2	deleterious	0,78	low_impact	-1,77	high_impact	1,88	medium_impact	-0,91	0,15	0,8	25,93	33,18	N	0,26	N	0,9	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11795	11795	C	G	MI.18506	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1036	346	Q	E	Caa/Gaa	-14,94	0	0	benign	0,05	deleterious	0,01	neutral	4,72	neutral	0,26	neutral	-1,02	medium_impact	2,42	neutral	0,68	neutral	0,51	neutral	1,33	12,43	0,47	0,55	disease	0,53	disease	0,63	disease	0,61	disease	0,7	4	deleterious	0,99	deleterious	0,48	deleterious	1	neutral	0,26	medium_impact	0,48	medium_impact	-0,92	medium_impact	1,27	0,28	0,8	41,83	8,78	N	0,37	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11795	11795	C	A	MI.18507	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1036	346	Q	K	Caa/Aaa	-14,94	0	0	benign	0,02	neutral	0,88	neutral	4,72	neutral	0,88	neutral	0,77	neutral_impact	-0,36	neutral	0,67	neutral	0,53	deleterious	2,22	17,62	0,45	0,55	neutral	0,5	neutral	0,43	neutral	0,36	neutral	0,35	3	neutral	0,07	deleterious	0,93	neutral	-6	neutral	0,22	medium_impact	0,87	medium_impact	0,69	low_impact	-1,48	0,33	0,8	41,83	8,78	N	0,28	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11796	11796	A	T	MI.18508	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1037	346	Q	L	cAa/cTa	4,4	0,99	0	benign	0,11	deleterious	0	neutral	4,61	neutral	-1,38	deleterious	-2,99	medium_impact	2,42	neutral	0,72	neutral	0,54	deleterious	2,08	16,73	0,16	0,45	disease	0,51	disease	0,63	disease	0,55	disease	0,68	4	deleterious	1	neutral	0,45	deleterious	1	neutral	0,3	medium_impact	0,14	low_impact	-1,48	medium_impact	1,27	0,28	0,8	41,83	8,78	P	0,56	P	0,81	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11796	11796	A	G	MI.18509	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1037	346	Q	R	cAa/cGa	4,4	0,99	0	benign	0	neutral	1	neutral	4,72	neutral	1,07	neutral	3,51	neutral_impact	-1,49	neutral	0,78	neutral	0,89	neutral	-1,05	0,01	0,55	0,6	neutral	0,23	neutral	0,13	neutral	0,25	neutral	0,25	5	neutral	0	deleterious	1	neutral	-6	neutral	0,13	high_impact	2,1	high_impact	1,88	low_impact	-2,6	0,17	0,8	41,83	8,78	N	0,45	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8558	8558	C	A	MI.1851	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	193	65	P	T	Ccc/Acc	1,05	0,01	0	probably_damaging	0,98	neutral	0,4	neutral	1,44	deleterious	-4,86	deleterious	-5,15	medium_impact	2,54	neutral	0,98	neutral	0,43	deleterious	3,94	23,5	0,67403744	0,85	disease	0,55	neutral	0,11	disease	0,56	neutral	0,19	6	deleterious	0,98	neutral	0,21	deleterious	1	deleterious	0,72	low_impact	-2,36	medium_impact	0,19	medium_impact	1,08	0,56	0,85	NA	NA	N	0,51	P	0,69	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11796	11796	A	C	MI.18510	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1037	346	Q	P	cAa/cCa	4,4	0,99	0	benign	0,36	deleterious	0	neutral	4,6	neutral	-1,92	deleterious	-2,95	medium_impact	2,42	neutral	0,61	neutral	0,35	neutral	1,75	14,67	0,08	0,35	neutral	0,26	disease	0,84	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,49	medium_impact	-0,48	low_impact	-1,48	medium_impact	1,27	0,3	0,8	41,83	8,78	N	0,46	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11797	11797	A	C	MI.18511	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1038	346	Q	H	caA/caC	2,79	1	0	possibly_damaging	0,49	deleterious	0	neutral	4,6	neutral	-1,33	neutral	-1,09	low_impact	1,62	neutral	0,72	neutral	0,55	deleterious	1,92	15,74	0,37	0,5	disease	0,63	neutral	0,47	disease	0,51	disease	0,59	2	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,59	medium_impact	-0,7	low_impact	-1,48	medium_impact	0,48	0,43	0,8	41,83	8,78	P	0,58	P	0,37	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11797	11797	A	T	MI.18512	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1038	346	Q	H	caA/caT	2,79	1	0	possibly_damaging	0,49	deleterious	0	neutral	4,6	neutral	-1,33	neutral	-1,09	low_impact	1,62	neutral	0,72	neutral	0,55	deleterious	2,05	16,54	0,37	0,5	disease	0,63	neutral	0,47	disease	0,51	disease	0,59	2	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,59	medium_impact	-0,7	low_impact	-1,48	medium_impact	0,48	0,43	0,8	41,83	8,78	P	0,57	P	0,37	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11798	11798	G	C	MI.18513	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1039	347	G	R	Gga/Cga	0,26	0,97	0	probably_damaging	1	deleterious	0	neutral	4,39	deleterious	-6,06	deleterious	-7,58	high_impact	4,24	neutral	0,72	damaging	0,1	deleterious	4,08	23,7	0,04	0,35	disease	0,95	disease	0,87	disease	0,84	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,07	0,65	0,8	47,06	9,29	N	0,5	N	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11798	11798	G	T	MI.18514	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1039	347	G	W	Gga/Tga	0,26	0,97	0	probably_damaging	1	deleterious	0	neutral	4,3	deleterious	-9,61	deleterious	-7,58	high_impact	4,59	neutral	0,72	damaging	0,11	deleterious	4,55	24,4	0,05	0,35	disease	0,99	disease	0,88	disease	0,81	disease	0,89	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,1	0,8	47,06	9,29	N	0,53	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11799	11799	G	C	MI.18515	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1040	347	G	A	gGa/gCa	6,01	1	0	probably_damaging	1	deleterious	0	neutral	4,39	deleterious	-5,04	deleterious	-5,68	high_impact	4,04	neutral	0,72	damaging	0,16	deleterious	3,18	22,7	0,08	0,35	disease	0,88	disease	0,65	disease	0,72	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,87	0,42	0,8	47,06	9,29	P	0,63	P	0,76	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11799	11799	G	A	MI.18516	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1040	347	G	E	gGa/gAa	6,01	1	0	probably_damaging	1	deleterious	0	neutral	4,39	deleterious	-5,5	deleterious	-7,58	high_impact	4,59	neutral	0,72	damaging	0,12	deleterious	4,05	23,7	0,04	0,35	disease	0,71	disease	0,85	disease	0,82	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,24	0,8	47,06	9,29	P	0,66	P	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11799	11799	G	T	MI.18517	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1040	347	G	V	gGa/gTa	6,01	1	0	probably_damaging	1	deleterious	0	neutral	4,33	deleterious	-6,36	deleterious	-8,53	high_impact	4,59	neutral	0,69	damaging	0,12	deleterious	3,9	23,5	0,03	0,35	disease	0,96	disease	0,86	disease	0,75	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,42	0,1	0,8	47,06	9,29	P	0,61	P	0,98	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11801	11801	C	T	MI.18518	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1042	348	L	F	Ctt/Ttt	-9,41	0	0	probably_damaging	1	neutral	0,17	neutral	4,23	deleterious	-5,05	deleterious	-3,42	medium_impact	2,31	neutral	0,71	neutral	0,28	deleterious	4,11	23,8	0,16	0,45	disease	0,75	disease	0,5	neutral	0,33	disease	0,5	0	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,18	medium_impact	1,16	0,28	0,8	45,32	8,56	N	0,3	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11801	11801	C	G	MI.18519	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1042	348	L	V	Ctt/Gtt	-9,41	0	0	probably_damaging	1	neutral	0,13	neutral	4,25	deleterious	-3,13	neutral	-2,39	medium_impact	2,41	neutral	0,71	damaging	0,19	deleterious	3,58	23,2	0,23	0,45	disease	0,71	disease	0,55	disease	0,63	disease	0,57	1	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,26	medium_impact	1,26	0,28	0,8	45,32	8,56	N	0,27	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8558	8558	C	T	MI.1852	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	193	65	P	S	Ccc/Tcc	1,05	0,01	0	probably_damaging	0,98	neutral	0,4	neutral	1,48	deleterious	-4,44	deleterious	-5,12	low_impact	1,54	neutral	0,99	neutral	0,67	deleterious	4,14	23,8	0,58173615	0,85	neutral	0,36	neutral	0,1	neutral	0,35	neutral	0,07	9	deleterious	0,98	neutral	0,21	neutral	-2	deleterious	0,69	low_impact	-2,36	medium_impact	0,19	medium_impact	0,22	0,28	0,85	NA	NA	P	0,6	P	0,61	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	C8558T	Possibly LVNC cardiomyopathy-associated	+	-	Reported	1
chrM	11801	11801	C	A	MI.18520	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1042	348	L	I	Ctt/Att	-9,41	0	0	probably_damaging	1	neutral	0,05	neutral	4,23	deleterious	-3,13	neutral	-1,61	medium_impact	2,4	neutral	0,71	damaging	0,23	deleterious	4,24	23,9	0,31	0,45	neutral	0,49	disease	0,59	neutral	0,43	neutral	0,49	0	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,25	0,51	0,8	45,32	8,56	N	0,33	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11802	11802	T	C	MI.18521	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1043	348	L	P	cTt/cCt	-1,12	0	0	probably_damaging	1	deleterious	0	neutral	4,13	deleterious	-6,56	deleterious	-6,01	high_impact	4,25	damaging	0,59	damaging	0,12	deleterious	4,12	23,8	0,03	0,35	disease	0,96	disease	0,86	disease	0,77	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,08	0,2	0,8	45,32	8,56	N	0,41	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11802	11802	T	A	MI.18522	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1043	348	L	H	cTt/cAt	-1,12	0	0	probably_damaging	1	deleterious	0	neutral	4,13	deleterious	-6,97	deleterious	-6,05	high_impact	4,25	neutral	0,65	damaging	0,11	deleterious	4,44	24,2	0,05	0,35	disease	0,96	disease	0,8	disease	0,73	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,08	0,22	0,8	45,32	8,56	N	0,36	N	0,96	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11802	11802	T	G	MI.18523	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1043	348	L	R	cTt/cGt	-1,12	0	0	probably_damaging	1	deleterious	0	neutral	4,14	deleterious	-6,17	deleterious	-5,14	high_impact	4,25	neutral	0,62	damaging	0,11	deleterious	4,42	24,2	0,02	0,35	disease	0,94	disease	0,88	disease	0,77	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,54	low_impact	-1,48	high_impact	3,08	0,15	0,8	45,32	8,56	N	0,42	N	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11804	11804	C	A	MI.18524	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1045	349	Q	K	Caa/Aaa	-5,5	0	0	probably_damaging	1	neutral	0,97	neutral	4,65	neutral	0,2	deleterious	-3,72	medium_impact	2,44	neutral	0,7	damaging	0,14	deleterious	4,07	23,7	0,28	0,45	neutral	0,32	disease	0,83	neutral	0,37	disease	0,51	0	deleterious	1	deleterious	0,49	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	1,05	medium_impact	1,29	0,3	0,8	47,93	9,07	N	0,21	N	0,98	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11804	11804	C	G	MI.18525	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1045	349	Q	E	Caa/Gaa	-5,5	0	0	probably_damaging	1	neutral	1	neutral	4,63	neutral	-0,63	deleterious	-2,81	medium_impact	2,78	neutral	0,71	damaging	0,15	deleterious	3,22	22,7	0,47	0,55	neutral	0,32	disease	0,78	disease	0,6	disease	0,66	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,73	low_impact	-3,54	high_impact	1,88	medium_impact	1,62	0,45	0,8	47,93	9,07	N	0,21	N	0,93	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11805	11805	A	T	MI.18526	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1046	349	Q	L	cAa/cTa	5,32	1	0	probably_damaging	1	neutral	0,74	neutral	4,8	neutral	2,36	deleterious	-6,41	low_impact	1,34	neutral	0,73	damaging	0,15	deleterious	3,98	23,6	0,11	0,4	neutral	0,26	disease	0,8	neutral	0,45	disease	0,5	0	deleterious	1	neutral	0,37	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	0,46	medium_impact	0,2	0,09	0,8	47,93	9,07	N	0,41	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11805	11805	A	G	MI.18527	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1046	349	Q	R	cAa/cGa	5,32	1	0	probably_damaging	1	neutral	0,65	neutral	4,7	neutral	1,26	deleterious	-3,72	medium_impact	3,08	neutral	0,65	damaging	0,15	deleterious	3,58	23,2	0,25	0,45	neutral	0,47	disease	0,88	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	0,35	medium_impact	1,92	0,12	0,8	47,93	9,07	N	0,51	P	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11805	11805	A	C	MI.18528	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1046	349	Q	P	cAa/cCa	5,32	1	0	probably_damaging	1	neutral	0,36	neutral	4,62	neutral	-1,28	deleterious	-5,6	high_impact	3,53	neutral	0,63	damaging	0,14	deleterious	3,47	23	0,07	0,35	disease	0,63	disease	0,91	disease	0,7	disease	0,77	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-3,54	medium_impact	0,06	high_impact	2,37	0,31	0,8	47,93	9,07	P	0,6	P	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11806	11806	A	C	MI.18529	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1047	349	Q	H	caA/caC	6,7	1	0	probably_damaging	1	neutral	0,46	neutral	4,62	neutral	-1,2	deleterious	-4,64	medium_impact	1,99	neutral	0,76	damaging	0,26	deleterious	3,54	23,1	0,35	0,5	disease	0,61	disease	0,75	neutral	0,35	disease	0,53	1	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,16	medium_impact	0,84	0,42	0,8	47,93	9,07	N	0,53	P	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8558	8558	C	G	MI.1853	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	193	65	P	A	Ccc/Gcc	1,05	0,01	0	probably_damaging	0,97	neutral	0,52	neutral	1,48	deleterious	-4,18	deleterious	-5,16	medium_impact	2,89	neutral	0,99	neutral	0,48	deleterious	3,33	22,9	0,54328946	0,85	neutral	0,43	neutral	0,05	disease	0,55	neutral	0,15	7	neutral	0,96	neutral	0,28	deleterious	1	deleterious	0,7	low_impact	-2,19	medium_impact	0,31	medium_impact	1,38	0,72	0,85	NA	NA	N	0,52	P	0,63	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11806	11806	A	T	MI.18530	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1047	349	Q	H	caA/caT	6,7	1	0	probably_damaging	1	neutral	0,46	neutral	4,62	neutral	-1,2	deleterious	-4,64	medium_impact	1,99	neutral	0,76	damaging	0,26	deleterious	3,69	23,3	0,35	0,5	disease	0,61	disease	0,75	neutral	0,35	disease	0,53	1	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	0,16	medium_impact	0,84	0,42	0,8	47,93	9,07	N	0,53	P	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11807	11807	A	G	MI.18531	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1048	350	T	A	Act/Gct	1,64	0,86	0	benign	0	neutral	0,85	neutral	4,66	neutral	0,07	neutral	-1,87	low_impact	1,1	neutral	0,71	neutral	0,85	deleterious	0,11	3,73	0,44	0,55	neutral	0,3	neutral	0,35	neutral	0,33	neutral	0,44	1	neutral	0,14	deleterious	0,93	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	0,62	medium_impact	-0,04	0,15	0,8	18,95	14,76	N	0,34	N	0,27	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11807	11807	A	T	MI.18532	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1048	350	T	S	Act/Tct	1,64	0,86	0	benign	0,01	neutral	0,77	neutral	4,63	neutral	0,52	neutral	-1,62	neutral_impact	0,58	neutral	0,76	neutral	0,94	deleterious	0,14	4	0,56	0,6	neutral	0,4	neutral	0,3	neutral	0,19	neutral	0,46	1	neutral	0,21	deleterious	0,88	neutral	-6	neutral	0,13	medium_impact	1,16	medium_impact	0,5	medium_impact	-0,55	0,61	0,8	18,95	14,76	N	0,32	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11807	11807	A	C	MI.18533	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1048	350	T	P	Act/Cct	1,64	0,86	0	benign	0,36	neutral	0,34	neutral	4,6	neutral	-1,64	deleterious	-3,31	low_impact	1,81	neutral	0,71	neutral	0,66	neutral	1,69	14,33	0,05	0,35	disease	0,66	disease	0,74	disease	0,53	disease	0,56	1	neutral	0,6	deleterious	0,49	neutral	-6	neutral	0,37	medium_impact	-0,48	medium_impact	0,04	medium_impact	0,67	0,2	0,8	18,95	14,76	N	0,32	N	0,91	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11808	11808	C	A	MI.18534	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1049	350	T	N	aCt/aAt	0,95	0,32	0	benign	0,23	neutral	0,69	neutral	4,71	neutral	-0,18	deleterious	-2,84	neutral_impact	0,66	neutral	0,76	neutral	0,74	deleterious	2,06	16,62	0,5	0,6	disease	0,73	neutral	0,43	neutral	0,2	disease	0,62	2	neutral	0,2	deleterious	0,73	neutral	-6	neutral	0,36	medium_impact	-0,23	medium_impact	0,4	medium_impact	-0,47	0,46	0,8	18,95	14,76	N	0,24	N	0,68	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11808	11808	C	G	MI.18535	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1049	350	T	S	aCt/aGt	0,95	0,32	0	benign	0,01	neutral	0,77	neutral	4,63	neutral	0,52	neutral	-1,62	neutral_impact	0,58	neutral	0,76	neutral	0,94	deleterious	0,49	7,36	0,56	0,6	neutral	0,4	neutral	0,3	neutral	0,19	neutral	0,46	1	neutral	0,21	deleterious	0,88	neutral	-6	neutral	0,13	medium_impact	1,16	medium_impact	0,5	medium_impact	-0,55	0,61	0,8	18,95	14,76	N	0,33	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11808	11808	C	T	MI.18536	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1049	350	T	I	aCt/aTt	0,95	0,32	0	benign	0	neutral	0,51	neutral	4,63	neutral	-1,81	neutral	-1,58	low_impact	1,17	neutral	0,72	neutral	0,99	deleterious	0,45	7,03	0,2	0,45	neutral	0,27	disease	0,56	neutral	0,2	neutral	0,42	2	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,11	high_impact	2,1	medium_impact	0,21	medium_impact	0,03	0,35	0,8	18,95	14,76	N	0,42	N	0,19	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11810	11810	C	G	MI.18537	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1051	351	L	V	Cta/Gta	-9,64	0	0,01	possibly_damaging	0,76	neutral	0,55	neutral	4,67	neutral	0,19	neutral	-0,24	low_impact	1,12	neutral	0,74	neutral	0,94	deleterious	2,12	16,99	0,34	0,5	neutral	0,41	neutral	0,2	neutral	0,3	neutral	0,38	2	neutral	0,73	neutral	0,4	neutral	-3	deleterious	0,65	low_impact	-1,19	medium_impact	0,25	medium_impact	-0,02	0,31	0,8	20,92	18,28	N	0,34	N	0,13	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11810	11810	C	A	MI.18538	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1051	351	L	M	Cta/Ata	-9,64	0	0,01	probably_damaging	0,98	neutral	0,24	neutral	4,58	neutral	-2,18	neutral	-0,59	low_impact	1,9	neutral	0,76	neutral	0,64	deleterious	2,7	20,8	0,24	0,45	disease	0,6	neutral	0,25	neutral	0,34	disease	0,55	1	deleterious	0,99	neutral	0,13	neutral	-2	deleterious	0,68	low_impact	-2,31	medium_impact	-0,08	medium_impact	0,75	0,46	0,8	20,92	18,28	N	0,41	N	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11811	11811	T	G	MI.18539	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1052	351	L	R	cTa/cGa	-6,19	0	0	probably_damaging	1	neutral	0,05	neutral	4,59	neutral	1,6	deleterious	-4,38	medium_impact	2,68	neutral	0,69	damaging	0,13	deleterious	4,19	23,8	0,1	0,4	disease	0,85	disease	0,83	disease	0,72	disease	0,79	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,53	0,2	0,8	20,92	18,28	N	0,28	N	0,9	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8559	8559	C	G	MI.1854	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	194	65	P	R	cCc/cGc	0,59	0,05	0	probably_damaging	0,99	neutral	0,35	neutral	1,43	deleterious	-5,34	deleterious	-5,73	medium_impact	2,54	neutral	0,99	neutral	0,28	deleterious	3,82	23,4	0,54328946	0,85	disease	0,72	neutral	0,12	disease	0,61	neutral	0,22	6	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,75	low_impact	-2,65	medium_impact	0,14	medium_impact	1,08	0,56	0,85	NA	NA	N	0,5	N	0,73	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11811	11811	T	C	MI.18540	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1052	351	L	P	cTa/cCa	-6,19	0	0	probably_damaging	1	neutral	0,05	neutral	4,57	neutral	-1,76	deleterious	-4,7	medium_impact	3,03	neutral	0,64	damaging	0,12	deleterious	3,94	23,5	0,04	0,35	disease	0,89	disease	0,83	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,87	0,17	0,8	20,92	18,28	N	0,23	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11811	11811	T	A	MI.18541	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1052	351	L	Q	cTa/cAa	-6,19	0	0	probably_damaging	1	neutral	0,08	neutral	4,57	neutral	-0,02	deleterious	-4,17	medium_impact	2,48	neutral	0,69	damaging	0,17	deleterious	4,1	23,7	0,12	0,4	disease	0,86	disease	0,57	disease	0,59	disease	0,7	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,39	medium_impact	1,33	0,21	0,8	20,92	18,28	N	0,31	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11813	11813	C	A	MI.18542	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1054	352	L	I	Ctc/Atc	-10,79	0	0	possibly_damaging	0,64	neutral	0,13	neutral	4,61	neutral	-0,65	neutral	-1,54	medium_impact	2,17	neutral	0,81	neutral	0,65	deleterious	2,44	19,07	0,34	0,5	disease	0,5	disease	0,51	disease	0,52	neutral	0,49	0	neutral	0,88	neutral	0,25	NA	0	neutral	0,35	medium_impact	-0,95	medium_impact	-0,26	medium_impact	1,02	0,51	0,8	20,26	17,44	N	0,36	N	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11813	11813	C	G	MI.18543	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1054	352	L	V	Ctc/Gtc	-10,79	0	0	possibly_damaging	0,64	neutral	0,12	neutral	4,6	neutral	-1,21	neutral	-2,49	medium_impact	2,58	neutral	0,74	neutral	0,48	neutral	1,76	14,78	0,31	0,45	neutral	0,38	neutral	0,41	disease	0,62	neutral	0,48	0	neutral	0,89	neutral	0,24	NA	0	neutral	0,32	medium_impact	-0,95	medium_impact	-0,28	medium_impact	1,43	0,41	0,8	20,26	17,44	N	0,43	N	0,4	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11813	11813	C	T	MI.18544	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1054	352	L	F	Ctc/Ttc	-10,79	0	0	benign	0,08	neutral	0,63	neutral	4,57	neutral	-2,48	neutral	-2,06	low_impact	0,96	neutral	0,79	neutral	0,95	deleterious	0,62	8,27	0,26	0,45	disease	0,51	neutral	0,29	neutral	0,4	neutral	0,33	3	neutral	0,28	deleterious	0,78	neutral	-6	neutral	0,17	medium_impact	0,28	medium_impact	0,33	medium_impact	-0,18	0,54	0,8	20,26	17,44	N	0,33	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11814	11814	T	C	MI.18545	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1055	352	L	P	cTc/cCc	-0,43	0	0	probably_damaging	0,98	deleterious	0,04	neutral	4,53	deleterious	-3,58	deleterious	-6,12	medium_impact	3,02	damaging	0,6	neutral	0,33	deleterious	3,98	23,6	0,02	0,35	disease	0,9	disease	0,81	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,8	low_impact	-2,31	medium_impact	-0,57	medium_impact	1,86	0,22	0,8	20,26	17,44	N	0,31	N	0,9	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11814	11814	T	G	MI.18546	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1055	352	L	R	cTc/cGc	-0,43	0	0	probably_damaging	0,95	neutral	0,06	neutral	4,56	neutral	-1,67	deleterious	-5,17	medium_impact	3,48	neutral	0,64	neutral	0,35	deleterious	4,16	23,8	0,02	0,35	disease	0,87	disease	0,83	disease	0,75	disease	0,8	6	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,79	low_impact	-1,92	medium_impact	-0,47	high_impact	2,32	0,29	0,8	20,26	17,44	N	0,36	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11814	11814	T	A	MI.18547	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1055	352	L	H	cTc/cAc	-0,43	0	0	probably_damaging	0,98	neutral	0,1	neutral	4,52	neutral	-2,35	deleterious	-5,6	medium_impact	3,48	neutral	0,7	neutral	0,41	deleterious	4,36	24,1	0,04	0,35	disease	0,9	disease	0,73	disease	0,71	disease	0,76	5	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,76	low_impact	-2,31	medium_impact	-0,33	high_impact	2,32	0,29	0,8	20,26	17,44	N	0,34	N	0,85	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11816	11816	C	G	MI.18548	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1057	353	P	A	Cca/Gca	-13,09	0	0	probably_damaging	1	deleterious	0	neutral	4,29	deleterious	-5,67	deleterious	-7,59	high_impact	3,99	neutral	0,61	damaging	0,17	deleterious	3,17	22,7	0,08	0,35	disease	0,58	disease	0,54	disease	0,7	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,54	low_impact	-1,48	high_impact	2,82	0,59	0,8	47,06	9,5	N	0,36	N	0,77	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11816	11816	C	T	MI.18549	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1057	353	P	S	Cca/Tca	-13,09	0	0	probably_damaging	1	neutral	0,05	neutral	4,26	deleterious	-5,74	deleterious	-7,59	medium_impact	2,62	damaging	0,57	damaging	0,19	deleterious	3,98	23,6	0,08	0,35	disease	0,66	disease	0,62	disease	0,69	disease	0,59	2	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,47	0,12	0,8	47,06	9,5	N	0,29	N	0,71	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8559	8559	C	A	MI.1855	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	194	65	P	H	cCc/cAc	0,59	0,05	0	probably_damaging	0,99	neutral	0,54	neutral	1,4	deleterious	-6,47	deleterious	-5,69	low_impact	1,8	neutral	0,98	neutral	0,41	deleterious	4,23	23,9	0,5073837	0,85	disease	0,83	neutral	0,15	neutral	0,41	neutral	0,13	7	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,78	low_impact	-2,65	medium_impact	0,33	medium_impact	0,45	0,56	0,85	NA	NA	N	0,37	N	0,29	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11816	11816	C	A	MI.18550	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1057	353	P	T	Cca/Aca	-13,09	0	0	probably_damaging	1	deleterious	0	neutral	4,25	deleterious	-6,12	deleterious	-7,59	high_impact	3,85	neutral	0,64	damaging	0,14	deleterious	3,77	23,4	0,06	0,35	disease	0,63	disease	0,62	disease	0,7	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,54	low_impact	-1,48	high_impact	2,68	0,5	0,8	47,06	9,5	N	0,33	N	0,89	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11817	11817	C	A	MI.18551	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1058	353	P	Q	cCa/cAa	7,17	1	0	probably_damaging	1	deleterious	0	neutral	4,25	deleterious	-5,9	deleterious	-7,59	high_impact	4,54	damaging	0,6	damaging	0,13	deleterious	4,16	23,8	0,06	0,35	disease	0,8	disease	0,76	disease	0,73	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	3,37	0,23	0,8	47,06	9,5	P	0,6	P	0,84	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11817	11817	C	G	MI.18552	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1058	353	P	R	cCa/cGa	7,17	1	0	probably_damaging	1	deleterious	0,01	neutral	4,29	deleterious	-5,25	deleterious	-8,54	high_impact	3,99	damaging	0,59	damaging	0,15	deleterious	3,67	23,3	0,03	0,35	disease	0,79	disease	0,82	disease	0,79	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,54	medium_impact	-0,92	high_impact	2,82	0,2	0,8	47,06	9,5	P	0,61	P	0,58	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11817	11817	C	T	MI.18553	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1058	353	P	L	cCa/cTa	7,17	1	0	probably_damaging	1	neutral	0,05	neutral	4,24	deleterious	-6,41	deleterious	-9,48	medium_impact	3,15	damaging	0,54	damaging	0,13	deleterious	4,46	24,2	0,05	0,35	disease	0,53	disease	0,79	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,99	0,64	0,8	47,06	9,5	N	0,5	N	0,97	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11819	11819	C	G	MI.18554	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1060	354	L	V	Cta/Gta	-14,71	0	0	probably_damaging	1	neutral	0,1	neutral	4,55	neutral	0,07	deleterious	-2,64	medium_impact	2,23	neutral	0,78	damaging	0,16	deleterious	3,51	23,1	0,41	0,5	disease	0,68	neutral	0,36	disease	0,53	disease	0,63	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,71	low_impact	-3,54	medium_impact	-0,33	medium_impact	1,08	0,51	0,8	46,84	8,63	N	0,26	N	0,89	polymorphism	1	0,05	rs28439211	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11819	11819	C	A	MI.18555	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1060	354	L	M	Cta/Ata	-14,71	0	0	probably_damaging	1	neutral	0,12	neutral	4,45	neutral	-2,58	neutral	-1,82	medium_impact	2,23	neutral	0,76	damaging	0,25	deleterious	3,87	23,5	0,29	0,45	disease	0,79	neutral	0,31	neutral	0,38	disease	0,62	2	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	-0,28	medium_impact	1,08	0,52	0,8	46,84	8,63	N	0,37	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11820	11820	T	G	MI.18556	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1061	354	L	R	cTa/cGa	0,95	0,35	0	probably_damaging	1	neutral	0,06	neutral	4,43	neutral	-2,31	deleterious	-5,62	medium_impact	2,68	neutral	0,73	damaging	0,13	deleterious	4,25	23,9	0,03	0,35	disease	0,94	disease	0,8	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,86	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,53	0,18	0,8	46,84	8,63	N	0,28	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11820	11820	T	A	MI.18557	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1061	354	L	Q	cTa/cAa	0,95	0,35	0	probably_damaging	1	neutral	0,05	neutral	4,43	deleterious	-3,74	deleterious	-5,58	medium_impact	3,38	neutral	0,72	damaging	0,13	deleterious	4,27	23,9	0,04	0,35	disease	0,9	disease	0,67	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,52	high_impact	2,22	0,16	0,8	46,84	8,63	N	0,34	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11820	11820	T	C	MI.18558	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1061	354	L	P	cTa/cCa	0,95	0,35	0	probably_damaging	1	deleterious	0,04	neutral	4,42	deleterious	-4,24	deleterious	-6,5	medium_impact	3,27	neutral	0,63	damaging	0,12	deleterious	4,04	23,7	0,02	0,35	disease	0,7	disease	0,76	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-3,54	medium_impact	-0,57	high_impact	2,11	0,19	0,8	46,84	8,63	N	0,32	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11822	11822	A	G	MI.18559	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1063	355	M	V	Ata/Gta	-5,5	0	0	possibly_damaging	0,45	deleterious	0,04	neutral	4,64	neutral	1,13	deleterious	-3,23	medium_impact	2,46	neutral	0,76	neutral	0,56	deleterious	2,82	21,5	0,25	0,45	neutral	0,37	disease	0,61	disease	0,64	disease	0,57	1	neutral	0,96	neutral	0,3	deleterious	4	deleterious	0,58	medium_impact	-0,64	medium_impact	-0,57	medium_impact	1,31	0,49	0,8	15,03	15,62	N	0,39	N	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8559	8559	C	T	MI.1856	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	194	65	P	L	cCc/cTc	0,59	0,05	0	probably_damaging	0,99	neutral	0,66	neutral	1,44	deleterious	-5,15	deleterious	-4,8	low_impact	1,8	neutral	0,99	neutral	0,64	deleterious	4,67	24,5	0,60355318	0,85	disease	0,73	neutral	0,12	neutral	0,36	neutral	0,11	8	deleterious	0,99	neutral	0,34	neutral	-2	deleterious	0,75	low_impact	-2,65	medium_impact	0,45	medium_impact	0,45	0,78	0,85	NA	NA	N	0,38	N	0,81	polymorphism	0,95	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11822	11822	A	T	MI.18560	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1063	355	M	L	Ata/Tta	-5,5	0	0	benign	0,02	neutral	0,48	neutral	4,79	neutral	2,33	neutral	-2,33	neutral_impact	0,6	neutral	0,67	neutral	0,63	deleterious	3,35	22,9	0,28	0,45	disease	0,57	disease	0,56	neutral	0,48	neutral	0,47	1	neutral	0,5	deleterious	0,73	neutral	-6	deleterious	0,54	medium_impact	0,87	medium_impact	0,18	medium_impact	-0,53	0,36	0,8	15,03	15,62	N	0,31	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11822	11822	A	C	MI.18561	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1063	355	M	L	Ata/Cta	-5,5	0	0	benign	0,02	neutral	0,48	neutral	4,79	neutral	2,33	neutral	-2,33	neutral_impact	0,6	neutral	0,67	neutral	0,63	deleterious	3,25	22,8	0,28	0,45	disease	0,57	disease	0,56	neutral	0,48	neutral	0,47	1	neutral	0,5	deleterious	0,73	neutral	-6	deleterious	0,54	medium_impact	0,87	medium_impact	0,18	medium_impact	-0,53	0,36	0,8	15,03	15,62	N	0,3	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11823	11823	T	C	MI.18562	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1064	355	M	T	aTa/aCa	3,71	0,99	0	benign	0,07	neutral	0,12	neutral	4,67	neutral	3,12	deleterious	-4,66	medium_impact	2,28	neutral	0,68	neutral	0,63	deleterious	1,84	15,2	0,12	0,4	disease	0,61	disease	0,59	disease	0,53	neutral	0,47	1	neutral	0,87	deleterious	0,53	neutral	-3	deleterious	0,71	medium_impact	0,34	medium_impact	-0,28	medium_impact	1,13	0,2	0,8	15,03	15,62	P	0,51	P	0,47	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11823	11823	T	A	MI.18563	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1064	355	M	K	aTa/aAa	3,71	0,99	0	possibly_damaging	0,66	deleterious	0	neutral	4,58	neutral	-1,88	deleterious	-5,11	high_impact	3,68	neutral	0,69	neutral	0,5	deleterious	4,32	24	0,03	0,35	disease	0,81	disease	0,82	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,17	deleterious	5	deleterious	0,78	medium_impact	-0,99	low_impact	-1,48	high_impact	2,52	0,17	0,8	15,03	15,62	P	0,59	P	0,94	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11824	11824	A	C	MI.18564	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1065	355	M	I	atA/atC	2,79	0,99	0	possibly_damaging	0,45	neutral	0,05	neutral	4,68	neutral	0,69	deleterious	-3,25	medium_impact	2,35	neutral	0,74	neutral	0,6	deleterious	3,42	23	0,31	0,45	disease	0,52	disease	0,73	disease	0,57	disease	0,59	2	neutral	0,94	neutral	0,3	NA	0	deleterious	0,67	medium_impact	-0,64	medium_impact	-0,52	medium_impact	1,2	0,41	0,8	15,03	15,62	P	0,55	P	0,84	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11824	11824	A	T	MI.18565	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1065	355	M	I	atA/atT	2,79	0,99	0	possibly_damaging	0,45	neutral	0,05	neutral	4,68	neutral	0,69	deleterious	-3,25	medium_impact	2,35	neutral	0,74	neutral	0,6	deleterious	3,58	23,2	0,31	0,45	disease	0,52	disease	0,73	disease	0,57	disease	0,59	2	neutral	0,94	neutral	0,3	NA	0	deleterious	0,67	medium_impact	-0,64	medium_impact	-0,52	medium_impact	1,2	0,41	0,8	15,03	15,62	P	0,55	P	0,84	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11825	11825	G	T	MI.18566	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1066	356	A	S	Gct/Tct	2,1	0,94	0	possibly_damaging	0,64	neutral	0,92	neutral	4,51	neutral	-1,92	neutral	-1,56	low_impact	0,98	neutral	0,65	neutral	0,58	neutral	0,91	10,13	0,21	0,45	disease	0,76	neutral	0,28	neutral	0,3	disease	0,6	2	neutral	0,59	deleterious	0,64	neutral	-3	neutral	0,35	medium_impact	-0,95	medium_impact	0,8	medium_impact	-0,16	0,49	0,8	25,49	20,39	N	0,35	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11825	11825	G	A	MI.18567	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1066	356	A	T	Gct/Act	2,1	0,94	0	benign	0,05	neutral	0,68	neutral	4,49	neutral	-1,94	neutral	-1,82	neutral_impact	0	neutral	0,75	neutral	0,91	deleterious	0,83	9,64	0,13	0,4	disease	0,86	neutral	0,11	neutral	0,25	neutral	0,39	2	neutral	0,25	deleterious	0,82	neutral	-6	neutral	0,17	medium_impact	0,48	medium_impact	0,39	low_impact	-1,13	0,7	0,85	25,49	20,39	N	0,38	N	0,5	polymorphism	1	0,03	rs879083692	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11825	11825	G	C	MI.18568	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1066	356	A	P	Gct/Cct	2,1	0,94	0	probably_damaging	0,93	neutral	0,05	neutral	4,41	deleterious	-4,55	deleterious	-3,55	medium_impact	2,5	neutral	0,65	neutral	0,34	deleterious	3,63	23,2	0,03	0,35	disease	0,97	disease	0,84	disease	0,69	disease	0,82	6	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,75	low_impact	-1,77	medium_impact	-0,52	medium_impact	1,35	0,5	0,8	25,49	20,39	N	0,42	N	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11826	11826	C	G	MI.18569	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1067	356	A	G	gCt/gGt	-0,66	0	0	benign	0,08	neutral	0,29	neutral	4,43	neutral	-1,66	deleterious	-2,6	low_impact	1,55	neutral	0,71	neutral	0,88	neutral	1,15	11,46	0,2	0,45	neutral	0,36	neutral	0,38	neutral	0,34	neutral	0,45	1	neutral	0,68	deleterious	0,61	neutral	-6	neutral	0,37	medium_impact	0,28	medium_impact	-0,02	medium_impact	0,41	0,64	0,8	25,49	20,39	N	0,48	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8561	8561	C	A	MI.1857	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	196	66	P	T	Cca/Aca	7,3	1	0	benign	0,03	neutral	0,53	neutral	1,95	neutral	-1,72	neutral	-1,19	low_impact	1,83	neutral	0,98	neutral	0,48	deleterious	3,8	23,4	0,3177178	0,85	neutral	0,34	neutral	0,02	neutral	0,41	neutral	0,05	9	neutral	0,44	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	0,68	medium_impact	0,32	medium_impact	0,47	0,46	0,85	NA	NA	P	0,6	P	0,51	disease_causing	0,91	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11826	11826	C	A	MI.18570	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1067	356	A	D	gCt/gAt	-0,66	0	0	possibly_damaging	0,87	deleterious	0,03	neutral	4,41	deleterious	-5,37	deleterious	-4,08	high_impact	3,6	neutral	0,73	neutral	0,36	deleterious	4,34	24	0,03	0,35	disease	0,98	disease	0,81	disease	0,68	disease	0,84	7	deleterious	0,99	neutral	0,08	deleterious	5	deleterious	0,7	low_impact	-1,49	medium_impact	-0,64	high_impact	2,44	0,35	0,8	25,49	20,39	N	0,4	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11826	11826	C	T	MI.18571	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1067	356	A	V	gCt/gTt	-0,66	0	0	possibly_damaging	0,64	neutral	0,11	neutral	4,47	neutral	-2,61	deleterious	-2,68	medium_impact	2,18	neutral	0,78	neutral	0,49	deleterious	2,71	20,9	0,11	0,4	disease	0,83	disease	0,55	disease	0,55	disease	0,67	3	neutral	0,9	neutral	0,24	NA	0	deleterious	0,46	medium_impact	-0,95	medium_impact	-0,31	medium_impact	1,03	0,58	0,8	25,49	20,39	N	0,38	N	0,45	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11828	11828	T	A	MI.18572	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1069	357	F	I	Ttt/Att	-9,87	0	0	benign	0	neutral	0,24	neutral	4,64	neutral	0,01	neutral	0,84	neutral_impact	0,64	neutral	0,74	neutral	0,86	neutral	1,39	12,74	0,17	0,45	disease	0,64	neutral	0,45	neutral	0,37	disease	0,6	2	neutral	0,76	deleterious	0,62	neutral	-6	neutral	0,17	high_impact	2,1	medium_impact	-0,08	medium_impact	-0,49	0,64	0,8	27,67	28,87	N	0,45	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11828	11828	T	G	MI.18573	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1069	357	F	V	Ttt/Gtt	-9,87	0	0	benign	0,06	neutral	0,26	neutral	4,66	neutral	0,16	neutral	1,17	neutral_impact	0,74	neutral	0,74	neutral	0,88	deleterious	0,84	9,69	0,15	0,4	disease	0,55	neutral	0,42	neutral	0,38	disease	0,59	2	neutral	0,72	deleterious	0,6	neutral	-6	neutral	0,14	medium_impact	0,41	medium_impact	-0,05	medium_impact	-0,39	0,49	0,8	27,67	28,87	N	0,44	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11828	11828	T	C	MI.18574	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1069	357	F	L	Ttt/Ctt	-9,87	0	0	benign	0	neutral	1	neutral	4,9	neutral	1,7	neutral	1,1	neutral_impact	-0,5	neutral	0,72	neutral	0,98	deleterious	0,78	9,36	0,22	0,45	disease	0,51	neutral	0,28	neutral	0,34	neutral	0,3	4	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,1	high_impact	1,88	low_impact	-1,62	0,62	0,8	27,67	28,87	N	0,26	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11829	11829	T	C	MI.18575	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1070	357	F	S	tTt/tCt	-4,58	0	0	benign	0,01	neutral	0,07	neutral	4,59	neutral	-0,77	neutral	1,29	low_impact	0,92	neutral	0,74	neutral	0,97	neutral	1,03	10,84	0,08	0,35	disease	0,74	neutral	0,36	neutral	0,4	disease	0,64	3	neutral	0,93	deleterious	0,53	neutral	-6	neutral	0,21	medium_impact	1,16	medium_impact	-0,43	medium_impact	-0,22	0,38	0,8	27,67	28,87	N	0,49	N	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11829	11829	T	G	MI.18576	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1070	357	F	C	tTt/tGt	-4,58	0	0	possibly_damaging	0,79	neutral	0,05	neutral	4,53	neutral	-2,88	neutral	0,07	medium_impact	2,17	neutral	0,76	neutral	0,46	deleterious	2,38	18,71	0,09	0,35	disease	0,91	disease	0,64	disease	0,56	disease	0,75	5	neutral	0,97	neutral	0,13	NA	0	deleterious	0,49	low_impact	-1,26	medium_impact	-0,52	medium_impact	1,02	0,35	0,8	27,67	28,87	N	0,4	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11829	11829	T	A	MI.18577	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1070	357	F	Y	tTt/tAt	-4,58	0	0	benign	0,31	deleterious	0,03	neutral	4,58	neutral	-1,13	neutral	-0,39	low_impact	1,47	neutral	0,78	neutral	0,62	deleterious	2,38	18,67	0,22	0,45	disease	0,77	neutral	0,39	neutral	0,46	disease	0,65	3	neutral	0,97	neutral	0,36	neutral	-2	neutral	0,21	medium_impact	-0,39	medium_impact	-0,64	medium_impact	0,33	0,63	0,8	27,67	28,87	N	0,41	N	0,33	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11830	11830	T	G	MI.18578	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1071	357	F	L	ttT/ttG	0,03	0	0	benign	0	neutral	1	neutral	4,9	neutral	1,7	neutral	1,1	neutral_impact	-0,5	neutral	0,72	neutral	0,98	neutral	1,09	11,17	0,22	0,45	disease	0,51	neutral	0,28	neutral	0,34	neutral	0,3	4	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,1	high_impact	1,88	low_impact	-1,62	0,62	0,8	27,67	28,87	N	0,36	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11830	11830	T	A	MI.18579	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1071	357	F	L	ttT/ttA	0,03	0	0	benign	0	neutral	1	neutral	4,9	neutral	1,7	neutral	1,1	neutral_impact	-0,5	neutral	0,72	neutral	0,98	neutral	1,11	11,29	0,22	0,45	disease	0,51	neutral	0,28	neutral	0,34	neutral	0,3	4	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,1	high_impact	1,88	low_impact	-1,62	0,62	0,8	27,67	28,87	N	0,36	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8561	8561	C	T	MI.1858	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	196	66	P	S	Cca/Tca	7,3	1	0	benign	0,06	neutral	0,72	neutral	1,96	neutral	-1,33	neutral	-1,01	low_impact	1,83	neutral	0,99	neutral	0,49	deleterious	4,18	23,8	0,37793802	0,85	neutral	0,31	neutral	0,02	neutral	0,41	neutral	0,05	9	neutral	0,2	deleterious	0,83	neutral	-6	neutral	0,12	medium_impact	0,38	medium_impact	0,52	medium_impact	0,47	0,31	0,85	NA	NA	P	0,62	P	0,44	disease_causing	0,91	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11831	11831	T	C	MI.18580	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1072	358	W	R	Tga/Cga	-8,26	0	0	probably_damaging	1	deleterious	0	neutral	4,62	neutral	-2,07	deleterious	-12,97	high_impact	3,9	neutral	0,71	damaging	0,12	deleterious	3,7	23,3	0,04	0,35	disease	0,77	disease	0,89	disease	0,81	disease	0,79	6	deleterious	1	deleterious	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,73	0,29	0,8	44,66	7,99	N	0,46	N	0,97	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11831	11831	T	G	MI.18581	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1072	358	W	G	Tga/Gga	-8,26	0	0	probably_damaging	1	deleterious	0,02	neutral	4,61	neutral	-0,19	deleterious	-12,03	medium_impact	3,1	neutral	0,69	damaging	0,15	deleterious	4,01	23,6	0,07	0,35	neutral	0,42	disease	0,79	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,71	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,94	0,23	0,8	44,66	7,99	N	0,41	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11832	11832	G	T	MI.18582	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1073	358	W	L	tGa/tTa	5,55	1	0	probably_damaging	1	neutral	0,25	neutral	4,87	neutral	2,09	deleterious	-12,03	medium_impact	2,04	neutral	0,68	damaging	0,14	deleterious	4,34	24	0,09	0,35	neutral	0,41	disease	0,83	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	-0,07	medium_impact	0,89	0,19	0,8	44,66	7,99	N	0,47	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11832	11832	G	C	MI.18583	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1073	358	W	S	tGa/tCa	5,55	1	0	probably_damaging	1	deleterious	0,02	neutral	4,73	neutral	0,08	deleterious	-12,89	medium_impact	3,15	neutral	0,64	damaging	0,22	deleterious	4,06	23,7	0,07	0,35	disease	0,54	disease	0,84	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,99	0,26	0,8	44,66	7,99	P	0,53	P	0,93	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11833	11833	A	C	MI.18584	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1074	358	W	C	tgA/tgC	7,17	1	0	probably_damaging	1	deleterious	0,01	neutral	4,69	neutral	-0,45	deleterious	-12,03	medium_impact	3,15	neutral	0,71	damaging	0,15	deleterious	4,23	23,9	0,09	0,35	disease	0,62	disease	0,86	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,99	0,28	0,8	44,66	7,99	P	0,54	P	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11833	11833	A	T	MI.18585	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1074	358	W	C	tgA/tgT	7,17	1	0	probably_damaging	1	deleterious	0,01	neutral	4,69	neutral	-0,45	deleterious	-12,03	medium_impact	3,15	neutral	0,71	damaging	0,15	deleterious	4,21	23,9	0,09	0,35	disease	0,62	disease	0,86	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,99	0,28	0,8	44,66	7,99	P	0,54	P	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11834	11834	T	C	MI.18586	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1075	359	W	R	Tga/Cga	3,25	1	0	probably_damaging	1	deleterious	0	neutral	4,57	neutral	-1,29	deleterious	-13,28	high_impact	3,92	damaging	0,54	damaging	0,07	deleterious	3,68	23,3	0,03	0,35	disease	0,76	disease	0,9	disease	0,82	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,75	0,22	0,8	46,41	9,31	P	0,58	P	0,97	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11834	11834	T	G	MI.18587	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1075	359	W	G	Tga/Gga	3,25	1	0	probably_damaging	1	deleterious	0	neutral	4,57	neutral	-0,41	deleterious	-12,33	high_impact	3,67	damaging	0,54	damaging	0,09	deleterious	4	23,6	0,05	0,35	disease	0,63	disease	0,81	disease	0,77	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,72	low_impact	-3,54	low_impact	-1,48	high_impact	2,51	0,22	0,8	46,41	9,31	P	0,54	P	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11835	11835	G	C	MI.18588	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1076	359	W	S	tGa/tCa	5,55	1	0	probably_damaging	1	deleterious	0,03	neutral	4,58	neutral	0,6	deleterious	-13,28	medium_impact	3,23	damaging	0,5	damaging	0,09	deleterious	4,1	23,7	0,05	0,35	disease	0,53	disease	0,86	disease	0,76	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,76	low_impact	-3,54	medium_impact	-0,64	high_impact	2,07	0,24	0,8	46,41	9,31	P	0,54	P	0,93	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11835	11835	G	T	MI.18589	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1076	359	W	L	tGa/tTa	5,55	1	0	probably_damaging	1	neutral	0,06	neutral	5,02	neutral	2,34	deleterious	-12,32	medium_impact	2,9	damaging	0,51	damaging	0,05	deleterious	4,35	24,1	0,08	0,35	neutral	0,41	disease	0,85	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,74	0,14	0,8	46,41	9,31	P	0,52	P	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8561	8561	C	G	MI.1859	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	196	66	P	A	Cca/Gca	7,3	1	0	benign	0,01	neutral	0,7	neutral	1,97	neutral	-1,24	neutral	-1,21	low_impact	1,83	neutral	0,99	neutral	0,61	deleterious	3,37	22,9	0,3819346	0,85	neutral	0,29	neutral	0,01	neutral	0,4	neutral	0,07	9	neutral	0,27	deleterious	0,85	neutral	-6	neutral	0,11	medium_impact	1,14	medium_impact	0,5	medium_impact	0,47	0,54	0,85	NA	NA	P	0,6	P	0,47	disease_causing	0,87	0,03	.	.	.	.	.	.	.	.	.	C8561G	Ataxia neuropathy,DM,SNHL and hypogonadism	+	+	Reported	1
chrM	11836	11836	A	T	MI.18590	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1077	359	W	C	tgA/tgT	9,01	1	0	probably_damaging	1	deleterious	0,01	neutral	4,56	neutral	-1,15	deleterious	-12,33	medium_impact	3,32	damaging	0,48	damaging	0,05	deleterious	4,23	23,9	0,04	0,35	disease	0,8	disease	0,86	disease	0,81	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,54	medium_impact	-0,92	high_impact	2,16	0,2	0,8	46,41	9,31	P	0,61	P	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11836	11836	A	C	MI.18591	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1077	359	W	C	tgA/tgC	9,01	1	0	probably_damaging	1	deleterious	0,01	neutral	4,56	neutral	-1,15	deleterious	-12,33	medium_impact	3,32	damaging	0,48	damaging	0,05	deleterious	4,09	23,7	0,04	0,35	disease	0,8	disease	0,86	disease	0,81	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,54	medium_impact	-0,92	high_impact	2,16	0,2	0,8	46,41	9,31	P	0,61	P	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11837	11837	C	A	MI.18592	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1078	360	L	I	Ctt/Att	0,95	0,3	0	possibly_damaging	0,74	neutral	0,06	neutral	4,59	neutral	-1,98	neutral	-1	medium_impact	2,01	neutral	0,81	neutral	0,81	deleterious	3,05	22,4	0,3	0,45	disease	0,73	disease	0,64	neutral	0,32	disease	0,53	1	neutral	0,95	neutral	0,16	NA	0	deleterious	0,74	low_impact	-1,14	medium_impact	-0,47	medium_impact	0,86	0,51	0,8	24,18	21,35	N	0,37	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11837	11837	C	G	MI.18593	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1078	360	L	V	Ctt/Gtt	0,95	0,3	0	possibly_damaging	0,74	neutral	0,07	neutral	4,53	neutral	-1,66	neutral	-1,8	medium_impact	2,38	neutral	0,83	neutral	0,61	deleterious	3,53	23,1	0,28	0,45	disease	0,68	disease	0,51	disease	0,55	disease	0,63	3	neutral	0,95	neutral	0,17	NA	0	deleterious	0,71	low_impact	-1,14	medium_impact	-0,43	medium_impact	1,23	0,51	0,8	24,18	21,35	N	0,37	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11837	11837	C	T	MI.18594	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1078	360	L	F	Ctt/Ttt	0,95	0,3	0	benign	0,08	neutral	1	neutral	4,5	neutral	-2,13	neutral	-1,53	neutral_impact	0,76	neutral	0,75	neutral	0,78	neutral	1,56	13,66	0,28	0,45	disease	0,74	neutral	0,1	neutral	0,3	neutral	0,43	2	neutral	0,08	deleterious	0,96	neutral	-6	deleterious	0,69	medium_impact	0,28	high_impact	1,88	medium_impact	-0,37	0,44	0,8	24,18	21,35	N	0,25	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11838	11838	T	A	MI.18595	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1079	360	L	H	cTt/cAt	-1,12	0	0	probably_damaging	0,98	deleterious	0	neutral	4,38	deleterious	-5,55	deleterious	-4,94	high_impact	4,03	neutral	0,72	neutral	0,43	deleterious	4,39	24,1	0,04	0,35	disease	0,77	disease	0,79	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,75	low_impact	-2,31	low_impact	-1,48	high_impact	2,86	0,31	0,8	24,18	21,35	N	0,39	N	0,96	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11838	11838	T	C	MI.18596	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1079	360	L	P	cTt/cCt	-1,12	0	0	probably_damaging	0,98	deleterious	0	neutral	4,38	deleterious	-5,59	deleterious	-5,45	high_impact	4,03	neutral	0,61	neutral	0,36	deleterious	4,07	23,7	0,03	0,35	disease	0,64	disease	0,88	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,31	low_impact	-1,48	high_impact	2,86	0,3	0,8	24,18	21,35	N	0,35	N	0,98	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11838	11838	T	G	MI.18597	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1079	360	L	R	cTt/cGt	-1,12	0	0	probably_damaging	0,97	deleterious	0	neutral	4,39	deleterious	-5,02	deleterious	-4,64	high_impact	4,03	neutral	0,66	neutral	0,4	deleterious	4,37	24,1	0,02	0,35	disease	0,63	disease	0,9	disease	0,68	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-2,14	low_impact	-1,48	high_impact	2,86	0,24	0,8	24,18	21,35	N	0,37	N	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11840	11840	C	A	MI.18598	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1081	361	L	M	Cta/Ata	-11,02	0	0	benign	0,03	neutral	0,14	neutral	4,37	neutral	-2,56	neutral	-0,78	low_impact	1,73	neutral	0,8	neutral	0,92	deleterious	0,54	7,73	0,19	0,45	disease	0,66	neutral	0,28	neutral	0,31	disease	0,57	1	neutral	0,85	deleterious	0,56	neutral	-6	neutral	0,16	medium_impact	0,7	medium_impact	-0,24	medium_impact	0,59	0,52	0,8	23,97	24,32	N	0,44	N	0,21	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11840	11840	C	G	MI.18599	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1081	361	L	V	Cta/Gta	-11,02	0	0	benign	0,01	neutral	0,23	neutral	4,56	neutral	0,07	neutral	-1,58	medium_impact	2,04	neutral	0,77	neutral	0,74	deleterious	0,48	7,27	0,21	0,45	disease	0,54	neutral	0,36	neutral	0,3	disease	0,54	1	neutral	0,77	deleterious	0,61	neutral	-3	neutral	0,18	medium_impact	1,16	medium_impact	-0,09	medium_impact	0,89	0,38	0,8	23,97	24,32	N	0,42	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8614	8614	T	G	MI.186	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	88	30	L	V	Ttg/Gtg	-20	0	0,01	probably_damaging	0,99	neutral	0,2	neutral	4,37	neutral	-0,15	neutral	-2,39	medium_impact	2,52	neutral	0,85	neutral	0,55	deleterious	3,24	22,8	0,48	0,65	disease	0,55	neutral	0,5	neutral	0,33	disease	0,51	0	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,76	low_impact	-2,65	medium_impact	-0,05	medium_impact	1,06	0,56	0,9	17,7	14,1	N	0,35	N	0,69	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8562	8562	C	G	MI.1860	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	197	66	P	R	cCa/cGa	4,52	1	0	benign	0,09	neutral	0,49	neutral	1,95	neutral	-1,56	neutral	-0,81	low_impact	1,14	neutral	0,99	neutral	0,37	deleterious	0,81	9,51	0,37202141	0,85	neutral	0,32	neutral	0,03	neutral	0,37	neutral	0,05	9	neutral	0,44	deleterious	0,7	neutral	-6	neutral	0,19	medium_impact	0,2	medium_impact	0,28	medium_impact	-0,12	0,34	0,85	NA	NA	P	0,61	P	0,55	disease_causing	0,96	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11841	11841	T	A	MI.18600	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1082	361	L	Q	cTa/cAa	-2,27	0	0	possibly_damaging	0,55	deleterious	0	neutral	4,33	deleterious	-4,52	deleterious	-4,56	high_impact	4,12	neutral	0,73	neutral	0,44	deleterious	2,41	18,87	0,03	0,35	disease	0,9	disease	0,72	disease	0,54	disease	0,71	4	deleterious	1	neutral	0,23	deleterious	5	deleterious	0,48	medium_impact	-0,8	low_impact	-1,48	high_impact	2,95	0,3	0,8	23,97	24,32	N	0,44	N	0,87	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11841	11841	T	C	MI.18601	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1082	361	L	P	cTa/cCa	-2,27	0	0	possibly_damaging	0,55	deleterious	0	neutral	4,33	deleterious	-4,9	deleterious	-5,45	medium_impact	3,42	neutral	0,66	neutral	0,37	deleterious	2,19	17,45	0,03	0,35	disease	0,92	disease	0,84	disease	0,66	disease	0,8	6	deleterious	1	neutral	0,23	deleterious	4	deleterious	0,53	medium_impact	-0,8	low_impact	-1,48	high_impact	2,26	0,26	0,8	23,97	24,32	N	0,29	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11841	11841	T	G	MI.18602	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1082	361	L	R	cTa/cGa	-2,27	0	0	possibly_damaging	0,55	deleterious	0	neutral	4,34	deleterious	-4,34	deleterious	-4,75	high_impact	4,12	neutral	0,71	neutral	0,38	deleterious	2,57	19,91	0,03	0,35	disease	0,89	disease	0,85	disease	0,66	disease	0,77	5	deleterious	1	neutral	0,23	deleterious	5	deleterious	0,5	medium_impact	-0,8	low_impact	-1,48	high_impact	2,95	0,18	0,8	23,97	24,32	N	0,4	N	0,93	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11843	11843	G	C	MI.18603	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1084	362	A	P	Gca/Cca	-1,12	0	0	probably_damaging	0,99	neutral	0,07	neutral	4,5	deleterious	-4,25	deleterious	-4,08	high_impact	3,52	neutral	0,69	neutral	0,37	deleterious	3,92	23,5	0,03	0,35	disease	0,67	disease	0,85	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,8	low_impact	-2,59	medium_impact	-0,43	high_impact	2,36	0,48	0,8	24,18	8,7	N	0,36	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11843	11843	G	T	MI.18604	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1084	362	A	S	Gca/Tca	-1,12	0	0	possibly_damaging	0,86	neutral	0,42	neutral	4,57	neutral	-2,52	neutral	-1,97	medium_impact	2,15	neutral	0,71	neutral	0,59	deleterious	2,64	20,4	0,21	0,45	disease	0,74	neutral	0,45	neutral	0,35	disease	0,63	3	neutral	0,85	neutral	0,28	NA	0	deleterious	0,73	low_impact	-1,46	medium_impact	0,12	medium_impact	1	0,44	0,8	24,18	8,7	N	0,42	N	0,32	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11843	11843	G	A	MI.18605	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1084	362	A	T	Gca/Aca	-1,12	0	0	probably_damaging	0,95	neutral	0,24	neutral	4,62	neutral	-2,97	deleterious	-2,84	medium_impact	2,12	neutral	0,71	neutral	0,59	deleterious	3,23	22,8	0,11	0,4	disease	0,83	neutral	0,46	neutral	0,36	disease	0,65	3	neutral	0,96	neutral	0,15	deleterious	1	deleterious	0,75	low_impact	-1,92	medium_impact	-0,08	medium_impact	0,97	0,66	0,8	24,18	8,7	N	0,41	N	0,84	polymorphism	1	0,07	rs28713729	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11844	11844	C	A	MI.18606	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1085	362	A	E	gCa/gAa	2,33	0,87	0	probably_damaging	0,98	neutral	0,09	neutral	4,51	deleterious	-4,8	deleterious	-3,98	high_impact	3,86	neutral	0,69	neutral	0,44	deleterious	4,62	24,5	0,03	0,35	disease	0,91	disease	0,79	disease	0,69	disease	0,78	6	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,82	low_impact	-2,31	medium_impact	-0,36	high_impact	2,69	0,3	0,8	24,18	8,7	N	0,5	N	0,89	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11844	11844	C	G	MI.18607	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1085	362	A	G	gCa/gGa	2,33	0,87	0	benign	0,15	neutral	0,16	neutral	4,62	neutral	0,31	deleterious	-3,19	medium_impact	2,48	neutral	0,78	neutral	0,71	deleterious	3,93	23,5	0,22	0,45	disease	0,63	disease	0,57	disease	0,55	disease	0,62	2	neutral	0,82	deleterious	0,51	neutral	-3	deleterious	0,72	medium_impact	-0,01	medium_impact	-0,2	medium_impact	1,33	0,56	0,8	24,18	8,7	N	0,33	N	0,64	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11844	11844	C	T	MI.18608	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1085	362	A	V	gCa/gTa	2,33	0,87	0	probably_damaging	0,96	neutral	0,42	neutral	4,63	neutral	-1,97	deleterious	-3,08	medium_impact	2,29	neutral	0,77	neutral	0,56	deleterious	4,51	24,3	0,12	0,4	disease	0,81	disease	0,59	neutral	0,4	disease	0,58	2	neutral	0,96	neutral	0,23	deleterious	1	deleterious	0,76	low_impact	-2,01	medium_impact	0,12	medium_impact	1,14	0,54	0,8	24,18	8,7	N	0,33	N	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11846	11846	A	G	MI.18609	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1087	363	S	G	Agc/Ggc	-4,58	0	0	benign	0,02	neutral	0,33	neutral	4,55	neutral	-1,9	deleterious	-2,52	medium_impact	2,33	neutral	0,78	neutral	0,73	deleterious	1,88	15,46	0,17	0,45	disease	0,77	disease	0,61	neutral	0,5	neutral	0,48	0	neutral	0,65	deleterious	0,66	neutral	-3	neutral	0,31	medium_impact	0,87	medium_impact	0,03	medium_impact	1,18	0,57	0,8	23,75	22,74	N	0,31	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8562	8562	C	T	MI.1861	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	197	66	P	L	cCa/cTa	4,52	1	0	benign	0	neutral	0,35	neutral	2,04	neutral	-2,06	neutral	-0,6	neutral_impact	-0,05	neutral	1	neutral	0,94	neutral	1,3	12,28	0,36046463	0,85	neutral	0,17	neutral	0,01	neutral	0,3	neutral	0,08	8	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,08	high_impact	2,09	medium_impact	0,14	low_impact	-1,14	0,56	0,85	NA	NA	P	0,62	P	0,22	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11846	11846	A	T	MI.18610	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1087	363	S	C	Agc/Tgc	-4,58	0	0	probably_damaging	0,94	neutral	0,39	neutral	4,59	neutral	-0,83	deleterious	-4,26	low_impact	0,82	neutral	0,76	neutral	0,87	deleterious	3,47	23	0,08	0,35	disease	0,82	disease	0,71	neutral	0,38	disease	0,62	2	neutral	0,95	neutral	0,23	neutral	-2	deleterious	0,71	low_impact	-1,84	medium_impact	0,09	medium_impact	-0,32	0,3	0,8	23,75	22,74	N	0,29	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11846	11846	A	C	MI.18611	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1087	363	S	R	Agc/Cgc	-4,58	0	0	possibly_damaging	0,57	neutral	0,36	neutral	4,53	neutral	-2,56	deleterious	-3,27	high_impact	3,64	neutral	0,67	neutral	0,39	deleterious	2,28	18,04	0,04	0,35	disease	0,74	disease	0,9	disease	0,72	disease	0,77	5	neutral	0,65	neutral	0,4	deleterious	1	deleterious	0,56	medium_impact	-0,83	medium_impact	0,06	high_impact	2,48	0,46	0,8	23,75	22,74	N	0,37	N	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11847	11847	G	C	MI.18612	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1088	363	S	T	aGc/aCc	2,1	0,02	0	benign	0,32	neutral	0,4	neutral	4,64	neutral	-0,03	neutral	-2,02	low_impact	1,42	neutral	0,76	neutral	0,87	neutral	1,63	14,04	0,31	0,45	neutral	0,46	disease	0,53	neutral	0,39	neutral	0,47	1	neutral	0,52	deleterious	0,54	neutral	-6	neutral	0,32	medium_impact	-0,41	medium_impact	0,1	medium_impact	0,28	0,56	0,8	23,75	22,74	N	0,36	N	0,73	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11847	11847	G	T	MI.18613	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1088	363	S	I	aGc/aTc	2,1	0,02	0	possibly_damaging	0,89	neutral	0,47	neutral	4,72	neutral	0,65	deleterious	-4,88	low_impact	1,9	neutral	0,69	neutral	0,54	deleterious	3,96	23,6	0,06	0,35	neutral	0,42	disease	0,89	disease	0,53	disease	0,65	3	neutral	0,88	neutral	0,29	neutral	-3	deleterious	0,64	low_impact	-1,57	medium_impact	0,17	medium_impact	0,75	0,39	0,8	23,75	22,74	N	0,31	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11847	11847	G	A	MI.18614	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1088	363	S	N	aGc/aAc	2,1	0,02	0	benign	0,01	neutral	0,48	neutral	4,56	neutral	-1,52	neutral	-0,08	neutral_impact	0,53	neutral	0,72	neutral	0,65	neutral	-0,49	0,24	0,41	0,5	neutral	0,41	neutral	0,25	neutral	0,37	neutral	0,44	1	neutral	0,51	deleterious	0,74	neutral	-6	neutral	0,15	medium_impact	1,16	medium_impact	0,18	medium_impact	-0,6	0,34	0,8	23,75	22,74	N	0,43	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11849	11849	C	T	MI.18615	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1090	364	L	F	Ctc/Ttc	0,26	0	0	benign	0,29	deleterious	0,04	neutral	4,3	neutral	-2,19	deleterious	-3,4	medium_impact	2,42	neutral	0,72	neutral	0,56	deleterious	4,08	23,7	0,2	0,45	neutral	0,37	disease	0,64	disease	0,59	disease	0,57	1	neutral	0,95	neutral	0,38	deleterious	1	deleterious	0,71	medium_impact	-0,35	medium_impact	-0,57	medium_impact	1,27	0,57	0,8	48,15	9,19	N	0,41	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11849	11849	C	A	MI.18616	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1090	364	L	I	Ctc/Atc	0,26	0	0	possibly_damaging	0,86	neutral	0,19	neutral	4,21	neutral	-2,52	neutral	-1,82	medium_impact	2,2	neutral	0,71	neutral	0,54	deleterious	4,15	23,8	0,28	0,45	disease	0,6	disease	0,58	disease	0,57	disease	0,51	0	neutral	0,92	neutral	0,17	NA	0	deleterious	0,74	low_impact	-1,46	medium_impact	-0,15	medium_impact	1,05	0,67	0,85	48,15	9,19	N	0,4	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11849	11849	C	G	MI.18617	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1090	364	L	V	Ctc/Gtc	0,26	0	0	possibly_damaging	0,86	neutral	0,25	neutral	4,23	neutral	-2,53	deleterious	-2,77	medium_impact	2,08	neutral	0,65	neutral	0,53	deleterious	3,52	23,1	0,26	0,45	neutral	0,5	neutral	0,42	disease	0,58	neutral	0,43	1	neutral	0,89	neutral	0,2	NA	0	deleterious	0,7	low_impact	-1,46	medium_impact	-0,07	medium_impact	0,93	0,49	0,8	48,15	9,19	N	0,37	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11850	11850	T	C	MI.18618	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1091	364	L	P	cTc/cCc	-0,43	0	0	probably_damaging	0,99	deleterious	0	neutral	4,14	deleterious	-6,33	deleterious	-6,52	high_impact	3,77	damaging	0,58	neutral	0,4	deleterious	4,02	23,6	0,02	0,35	disease	0,89	disease	0,82	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,59	low_impact	-1,48	high_impact	2,6	0,28	0,8	48,15	9,19	N	0,39	N	0,98	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11850	11850	T	A	MI.18619	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1091	364	L	H	cTc/cAc	-0,43	0	0	probably_damaging	0,99	deleterious	0	neutral	4,14	deleterious	-6,29	deleterious	-6,41	high_impact	4,12	neutral	0,65	neutral	0,36	deleterious	4,27	23,9	0,04	0,35	disease	0,94	disease	0,76	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,59	low_impact	-1,48	high_impact	2,95	0,33	0,8	48,15	9,19	N	0,34	N	0,96	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8562	8562	C	A	MI.1862	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	197	66	P	Q	cCa/cAa	4,52	1	0	benign	0,19	neutral	0,71	neutral	2,01	neutral	-0,67	neutral	1,12	neutral_impact	-0,76	neutral	0,99	neutral	0,96	neutral	1,54	13,53	0,34743468	0,85	neutral	0,19	neutral	0,02	neutral	0,28	neutral	0,07	9	neutral	0,18	deleterious	0,76	neutral	-6	neutral	0,24	medium_impact	-0,16	medium_impact	0,51	low_impact	-1,75	0,33	0,85	NA	NA	N	0,5	N	0,12	disease_causing	0,93	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11850	11850	T	G	MI.18620	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1091	364	L	R	cTc/cGc	-0,43	0	0	probably_damaging	0,98	deleterious	0	neutral	4,15	deleterious	-5,76	deleterious	-5,57	high_impact	4,12	damaging	0,58	neutral	0,35	deleterious	4,31	24	0,02	0,35	disease	0,92	disease	0,86	disease	0,76	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,31	low_impact	-1,48	high_impact	2,95	0,19	0,8	48,15	9,19	N	0,4	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11852	11852	G	T	MI.18621	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1093	365	A	S	Gct/Tct	-4,81	0	0	benign	0,4	neutral	0,91	neutral	4,88	neutral	-0,91	neutral	-0,69	low_impact	1,07	neutral	0,68	neutral	0,79	deleterious	0,88	9,96	0,27	0,45	disease	0,66	neutral	0,47	neutral	0,32	disease	0,6	2	neutral	0,32	deleterious	0,76	neutral	-6	neutral	0,3	medium_impact	-0,55	medium_impact	0,77	medium_impact	-0,07	0,45	0,8	23,31	15,3	N	0,26	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11852	11852	G	A	MI.18622	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1093	365	A	T	Gct/Act	-4,81	0	0	benign	0,02	neutral	0,57	neutral	4,51	deleterious	-3,37	neutral	-0,26	neutral_impact	0,08	neutral	0,79	neutral	0,92	deleterious	0,51	7,53	0,13	0,4	neutral	0,4	neutral	0,26	neutral	0,32	neutral	0,45	1	neutral	0,4	deleterious	0,78	neutral	-6	neutral	0,13	medium_impact	0,87	medium_impact	0,27	low_impact	-1,05	0,75	0,85	23,31	15,3	N	0,28	N	0,01	polymorphism	1	0,02	rs373915038	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11852	11852	G	C	MI.18623	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1093	365	A	P	Gct/Cct	-4,81	0	0	possibly_damaging	0,79	deleterious	0,03	neutral	4,45	deleterious	-5,61	deleterious	-2,85	medium_impact	3,4	neutral	0,66	neutral	0,36	deleterious	3,63	23,2	0,04	0,35	disease	0,71	disease	0,92	disease	0,73	disease	0,79	6	neutral	0,98	neutral	0,12	deleterious	4	deleterious	0,66	low_impact	-1,26	medium_impact	-0,64	high_impact	2,24	0,52	0,8	23,31	15,3	N	0,35	N	0,78	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11853	11853	C	A	MI.18624	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1094	365	A	D	gCt/gAt	0,26	0	0	possibly_damaging	0,73	deleterious	0,03	neutral	4,46	deleterious	-4,93	deleterious	-3,14	medium_impact	3,4	neutral	0,7	neutral	0,4	deleterious	4,21	23,9	0,03	0,35	disease	0,84	disease	0,88	disease	0,71	disease	0,78	6	neutral	0,98	neutral	0,15	deleterious	4	deleterious	0,67	low_impact	-1,12	medium_impact	-0,64	high_impact	2,24	0,31	0,8	23,31	15,3	N	0,34	N	0,83	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11853	11853	C	G	MI.18625	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1094	365	A	G	gCt/gGt	0,26	0	0	benign	0,4	neutral	0,14	neutral	4,49	neutral	-2,92	deleterious	-2,57	low_impact	1,61	neutral	0,72	neutral	0,59	deleterious	2,3	18,17	0,21	0,45	disease	0,51	disease	0,64	neutral	0,5	disease	0,51	0	neutral	0,84	neutral	0,37	neutral	-6	neutral	0,32	medium_impact	-0,55	medium_impact	-0,24	medium_impact	0,47	0,65	0,8	23,31	15,3	N	0,34	N	0,55	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11853	11853	C	T	MI.18626	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1094	365	A	V	gCt/gTt	0,26	0	0	benign	0,4	neutral	0,19	neutral	4,5	deleterious	-3,96	neutral	-2,01	low_impact	1,8	neutral	0,74	neutral	0,57	deleterious	2,71	20,9	0,07	0,35	disease	0,52	disease	0,69	disease	0,52	disease	0,58	2	neutral	0,78	neutral	0,4	neutral	-6	neutral	0,36	medium_impact	-0,55	medium_impact	-0,15	medium_impact	0,66	0,73	0,85	23,31	15,3	N	0,36	N	0,52	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11855	11855	A	G	MI.18627	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1096	366	N	D	Aac/Gac	-11,02	0	0	probably_damaging	1	deleterious	0	neutral	4,5	deleterious	-3,37	deleterious	-4,74	high_impact	4,58	neutral	0,61	damaging	0,14	deleterious	3,93	23,5	0,31	0,5	disease	0,89	disease	0,71	disease	0,76	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,54	low_impact	-1,48	high_impact	3,41	0,26	0,8	46,62	9,19	N	0,49	N	0,96	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11855	11855	A	T	MI.18628	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1096	366	N	Y	Aac/Tac	-11,02	0	0	probably_damaging	1	deleterious	0	neutral	4,56	neutral	-1,4	deleterious	-7,59	high_impact	4,24	damaging	0,58	damaging	0,11	deleterious	3,83	23,4	0,07	0,35	disease	0,7	disease	0,83	disease	0,74	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3,07	0,2	0,8	46,62	9,19	N	0,38	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11855	11855	A	C	MI.18629	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1096	366	N	H	Aac/Cac	-11,02	0	0	probably_damaging	1	deleterious	0,01	neutral	4,5	neutral	-2,81	deleterious	-4,74	high_impact	4,58	damaging	0,58	damaging	0,12	deleterious	3,13	22,6	0,24	0,45	disease	0,85	disease	0,78	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-3,54	medium_impact	-0,92	high_impact	3,41	0,24	0,8	46,62	9,19	N	0,5	N	0,97	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8564	8564	C	A	MI.1863	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	199	67	Q	K	Caa/Aaa	0,13	0	0	benign	0	neutral	0,3	neutral	1,79	neutral	-0,73	neutral	-2,31	medium_impact	2,96	neutral	0,98	neutral	0,3	deleterious	4,16	23,8	0,7141844	0,85	neutral	0,25	neutral	0,06	disease	0,55	neutral	0,15	7	neutral	0,7	deleterious	0,65	neutral	-3	neutral	0,17	high_impact	2,09	medium_impact	0,08	medium_impact	1,44	0,71	0,85	NA	NA	N	0,5	N	0,62	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11856	11856	A	T	MI.18630	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1097	366	N	I	aAc/aTc	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,6	neutral	1,85	deleterious	-8,54	high_impact	4,58	damaging	0,58	damaging	0,15	deleterious	4	23,6	0,12	0,4	neutral	0,41	disease	0,89	disease	0,68	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,54	low_impact	-1,48	high_impact	3,41	0,2	0,8	46,62	9,19	P	0,61	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11856	11856	A	C	MI.18631	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1097	366	N	T	aAc/aCc	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,54	neutral	0	deleterious	-5,69	high_impact	3,68	neutral	0,64	damaging	0,14	deleterious	3,45	23	0,21	0,45	disease	0,6	disease	0,74	disease	0,65	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,54	low_impact	-1,48	high_impact	2,52	0,29	0,8	46,62	9,19	P	0,59	P	0,95	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11856	11856	A	G	MI.18632	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1097	366	N	S	aAc/aGc	8,55	1	0	probably_damaging	1	deleterious	0,03	neutral	4,58	neutral	1,02	deleterious	-4,74	medium_impact	2,48	damaging	0,58	damaging	0,17	deleterious	3,21	22,7	0,46	0,55	disease	0,63	disease	0,72	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,76	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,33	0,19	0,8	46,62	9,19	P	0,59	P	0,85	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11857	11857	C	G	MI.18633	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1098	366	N	K	aaC/aaG	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,51	neutral	-2,15	deleterious	-5,69	high_impact	4,58	damaging	0,56	damaging	0,12	deleterious	4,09	23,7	0,21	0,45	disease	0,8	disease	0,81	disease	0,77	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,41	0,32	0,8	46,62	9,19	P	0,66	P	0,99	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11857	11857	C	A	MI.18634	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1098	366	N	K	aaC/aaA	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,51	neutral	-2,15	deleterious	-5,69	high_impact	4,58	damaging	0,56	damaging	0,12	deleterious	4,56	24,4	0,21	0,45	disease	0,8	disease	0,81	disease	0,77	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,41	0,32	0,8	46,62	9,19	P	0,66	P	0,99	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11858	11858	C	T	MI.18635	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1099	367	L	F	Ctc/Ttc	-1,12	0	0	probably_damaging	0,97	deleterious	0,04	neutral	4,5	neutral	-2,78	deleterious	-3,53	medium_impact	2,12	neutral	0,69	neutral	0,45	deleterious	4,04	23,7	0,26	0,45	disease	0,76	disease	0,68	disease	0,61	disease	0,69	4	deleterious	0,99	neutral	0,04	deleterious	5	deleterious	0,76	low_impact	-2,14	medium_impact	-0,57	medium_impact	0,97	0,52	0,8	45,32	9,01	N	0,32	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11858	11858	C	G	MI.18636	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1099	367	L	V	Ctc/Gtc	-1,12	0	0	possibly_damaging	0,86	deleterious	0,03	neutral	4,59	neutral	-0,37	deleterious	-2,58	medium_impact	2,35	neutral	0,81	neutral	0,5	deleterious	3,51	23,1	0,35	0,5	disease	0,59	neutral	0,49	neutral	0,5	disease	0,57	1	deleterious	0,98	neutral	0,09	deleterious	4	deleterious	0,71	low_impact	-1,46	medium_impact	-0,64	medium_impact	1,2	0,42	0,8	45,32	9,01	N	0,38	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11858	11858	C	A	MI.18637	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1099	367	L	I	Ctc/Atc	-1,12	0	0	possibly_damaging	0,86	neutral	0,1	neutral	4,61	neutral	-0,34	neutral	-1,76	low_impact	1,55	neutral	0,73	neutral	0,66	deleterious	4,32	24	0,32	0,5	disease	0,64	disease	0,53	neutral	0,3	neutral	0,48	0	neutral	0,95	neutral	0,12	neutral	-3	deleterious	0,73	low_impact	-1,46	medium_impact	-0,33	medium_impact	0,41	0,55	0,8	45,32	9,01	N	0,42	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11859	11859	T	A	MI.18638	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1100	367	L	H	cTc/cAc	-0,2	0	0	probably_damaging	0,99	deleterious	0	neutral	4,48	deleterious	-4,56	deleterious	-6,24	high_impact	3,67	neutral	0,71	neutral	0,34	deleterious	4,26	23,9	0,06	0,35	disease	0,73	disease	0,78	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,59	low_impact	-1,48	high_impact	2,51	0,2	0,8	45,32	9,01	N	0,32	N	0,96	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11859	11859	T	C	MI.18639	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1100	367	L	P	cTc/cCc	-0,2	0	0	probably_damaging	0,99	deleterious	0	neutral	4,48	deleterious	-4,61	deleterious	-6,24	medium_impact	3,33	neutral	0,61	neutral	0,33	deleterious	4,01	23,6	0,03	0,35	disease	0,82	disease	0,89	disease	0,6	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,85	low_impact	-2,59	low_impact	-1,48	high_impact	2,17	0,24	0,8	45,32	9,01	N	0,29	N	0,98	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8564	8564	C	G	MI.1864	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	199	67	Q	E	Caa/Gaa	0,13	0	0	benign	0,01	neutral	0,28	neutral	1,72	neutral	-1,53	neutral	-1,75	medium_impact	2,96	neutral	0,97	neutral	0,38	deleterious	4,08	23,7	0,74880421	0,85	neutral	0,4	neutral	0,04	disease	0,55	neutral	0,14	7	neutral	0,71	deleterious	0,64	neutral	-3	neutral	0,17	medium_impact	1,14	medium_impact	0,06	medium_impact	1,44	0,74	0,85	NA	NA	N	0,49	N	0,59	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11859	11859	T	G	MI.18640	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1100	367	L	R	cTc/cGc	-0,2	0	0	probably_damaging	0,98	deleterious	0	neutral	4,49	deleterious	-4,03	deleterious	-5,29	high_impact	3,67	neutral	0,66	neutral	0,32	deleterious	4,31	24	0,04	0,35	disease	0,69	disease	0,88	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,31	low_impact	-1,48	high_impact	2,51	0,15	0,8	45,32	9,01	N	0,33	N	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11861	11861	G	C	MI.18641	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1102	368	A	P	Gcc/Ccc	-2,73	0	0	probably_damaging	1	neutral	0,05	neutral	4,43	deleterious	-4,7	deleterious	-4,63	medium_impact	3,23	neutral	0,66	damaging	0,11	deleterious	3,89	23,5	0,04	0,35	neutral	0,37	disease	0,87	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,52	high_impact	2,07	0,28	0,8	46,41	8,92	N	0,29	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11861	11861	G	A	MI.18642	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1102	368	A	T	Gcc/Acc	-2,73	0	0	probably_damaging	1	deleterious	0	neutral	4,5	neutral	-2,92	deleterious	-3,72	high_impact	4,03	neutral	0,65	damaging	0,11	deleterious	4,33	24	0,06	0,35	neutral	0,38	disease	0,78	disease	0,63	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,54	low_impact	-1,48	high_impact	2,86	0,61	0,8	46,41	8,92	N	0,37	N	0,82	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11861	11861	G	T	MI.18643	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1102	368	A	S	Gcc/Tcc	-2,73	0	0	probably_damaging	1	neutral	0,24	neutral	4,51	neutral	-1,6	deleterious	-2,74	medium_impact	2,09	neutral	0,61	damaging	0,2	deleterious	3,79	23,4	0,11	0,4	disease	0,52	disease	0,77	disease	0,52	disease	0,58	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,08	medium_impact	0,94	0,34	0,8	46,41	8,92	N	0,31	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11862	11862	C	A	MI.18644	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1103	368	A	D	gCc/gAc	6,01	1	0	probably_damaging	1	deleterious	0	neutral	4,42	deleterious	-5,17	deleterious	-5,51	high_impact	4,38	neutral	0,7	damaging	0,09	deleterious	4,66	24,5	0,03	0,35	disease	0,89	disease	0,9	disease	0,74	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,21	0,18	0,8	46,41	8,92	P	0,6	P	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11862	11862	C	G	MI.18645	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1103	368	A	G	gCc/gGc	6,01	1	0	probably_damaging	1	neutral	0,39	neutral	5,47	neutral	3,61	deleterious	-3,45	low_impact	1,82	neutral	0,64	damaging	0,17	deleterious	4,06	23,7	0,14	0,4	disease	0,62	disease	0,62	neutral	0,46	neutral	0,46	1	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,73	low_impact	-3,54	medium_impact	0,09	medium_impact	0,68	0,52	0,8	46,41	8,92	P	0,56	P	0,79	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11862	11862	C	T	MI.18646	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1103	368	A	V	gCc/gTc	6,01	1	0	probably_damaging	1	deleterious	0	neutral	4,44	deleterious	-3,42	deleterious	-3,75	high_impact	4,38	neutral	0,62	damaging	0,12	deleterious	4,62	24,5	0,05	0,35	neutral	0,41	disease	0,77	disease	0,64	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,54	low_impact	-1,48	high_impact	3,21	0,56	0,8	46,41	8,92	P	0,57	P	0,72	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11864	11864	T	G	MI.18647	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1105	369	L	V	Tta/Gta	-6,19	0	0	probably_damaging	1	neutral	0,34	neutral	4,41	neutral	-1,44	deleterious	-2,75	medium_impact	2,23	neutral	0,7	neutral	0,53	deleterious	3,5	23,1	0,38	0,5	disease	0,77	neutral	0,46	neutral	0,49	disease	0,63	3	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	0,04	medium_impact	1,08	0,49	0,8	43,14	7,89	N	0,33	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11864	11864	T	A	MI.18648	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1105	369	L	M	Tta/Ata	-6,19	0	0	probably_damaging	1	neutral	0,09	neutral	4,35	neutral	-2,76	neutral	-1,82	low_impact	1,92	neutral	0,78	neutral	0,65	deleterious	3,66	23,2	0,36	0,5	disease	0,78	neutral	0,47	neutral	0,45	disease	0,61	2	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,74	low_impact	-3,54	medium_impact	-0,36	medium_impact	0,77	0,46	0,8	43,14	7,89	N	0,36	N	0,9	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11865	11865	T	G	MI.18649	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1106	369	L	W	tTa/tGa	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	4,31	deleterious	-6,56	deleterious	-5,58	high_impact	3,68	neutral	0,68	neutral	0,39	deleterious	3,88	23,5	0,05	0,35	disease	0,68	disease	0,69	disease	0,62	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,54	low_impact	-1,48	high_impact	2,52	0,28	0,8	43,14	7,89	N	0,35	N	0,98	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8565	8565	A	G	MI.1865	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	200	67	Q	R	cAa/cGa	0,59	0	0	benign	0	neutral	0,38	neutral	1,78	neutral	-0,7	neutral	-2,22	low_impact	1,81	neutral	1	neutral	0,58	deleterious	0,53	7,66	0,83186441	0,9	neutral	0,19	neutral	0,05	neutral	0,48	neutral	0,05	9	neutral	0,62	deleterious	0,69	neutral	-6	neutral	0,14	high_impact	2,09	medium_impact	0,17	medium_impact	0,45	0,55	0,85	NA	NA	N	0,52	P	0,55	polymorphism	1	0,08	rs878853052	Uncertain significance	not_provided	RCV000224966.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	11865	11865	T	C	MI.18650	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1106	369	L	S	tTa/tCa	-0,2	0	0	probably_damaging	1	neutral	0,07	neutral	4,34	deleterious	-3,99	deleterious	-5,53	medium_impact	2,37	neutral	0,73	neutral	0,47	deleterious	3,84	23,4	0,03	0,35	disease	0,94	disease	0,66	disease	0,62	disease	0,8	6	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,8	low_impact	-3,54	medium_impact	-0,43	medium_impact	1,22	0,35	0,8	43,14	7,89	N	0,31	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11866	11866	A	T	MI.18651	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1107	369	L	F	ttA/ttT	5,55	0,87	0	probably_damaging	1	neutral	0,22	neutral	4,36	neutral	-2,73	deleterious	-3,72	medium_impact	2,23	neutral	0,72	neutral	0,54	deleterious	3,66	23,2	0,29	0,45	disease	0,79	disease	0,61	neutral	0,5	disease	0,53	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,11	medium_impact	1,08	0,37	0,8	43,14	7,89	P	0,5	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11866	11866	A	C	MI.18652	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1107	369	L	F	ttA/ttC	5,55	0,87	0	probably_damaging	1	neutral	0,22	neutral	4,36	neutral	-2,73	deleterious	-3,72	medium_impact	2,23	neutral	0,72	neutral	0,54	deleterious	3,54	23,1	0,29	0,45	disease	0,79	disease	0,61	neutral	0,5	disease	0,53	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,11	medium_impact	1,08	0,37	0,8	43,14	7,89	N	0,5	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11867	11867	C	G	MI.18653	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1108	370	P	A	Ccc/Gcc	-9,64	0	0	probably_damaging	1	deleterious	0	neutral	3,56	deleterious	-5,9	deleterious	-7,47	high_impact	4,62	damaging	0,51	damaging	0,11	deleterious	3,19	22,7	0,05	0,35	neutral	0,43	disease	0,62	disease	0,77	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,42	0,8	47,06	9,43	N	0,45	N	0,77	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11867	11867	C	A	MI.18654	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1108	370	P	T	Ccc/Acc	-9,64	0	0	probably_damaging	1	deleterious	0	neutral	3,54	deleterious	-6,35	deleterious	-7,47	high_impact	3,92	damaging	0,56	damaging	0,08	deleterious	3,75	23,3	0,05	0,35	neutral	0,36	disease	0,77	disease	0,73	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,54	low_impact	-1,48	high_impact	2,75	0,35	0,8	47,06	9,43	N	0,34	N	0,89	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11867	11867	C	T	MI.18655	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1108	370	P	S	Ccc/Tcc	-9,64	0	0	probably_damaging	1	deleterious	0	neutral	3,54	deleterious	-6,59	deleterious	-7,47	high_impact	4,62	damaging	0,53	damaging	0,09	deleterious	3,99	23,6	0,04	0,35	disease	0,52	disease	0,8	disease	0,76	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,19	0,8	47,06	9,43	N	0,43	N	0,71	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11868	11868	C	A	MI.18656	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1109	370	P	H	cCc/cAc	4,4	0,99	0	probably_damaging	1	deleterious	0	neutral	3,52	deleterious	-8,05	deleterious	-8,4	high_impact	4,62	damaging	0,56	damaging	0,06	deleterious	4,22	23,9	0,04	0,35	disease	0,82	disease	0,85	disease	0,83	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,27	0,8	47,06	9,43	P	0,59	P	0,7	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11868	11868	C	T	MI.18657	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1109	370	P	L	cCc/cTc	4,4	0,99	0	probably_damaging	1	deleterious	0	neutral	3,62	deleterious	-5,06	deleterious	-9,34	high_impact	4,07	damaging	0,52	damaging	0,06	deleterious	4,44	24,2	0,04	0,35	disease	0,78	disease	0,87	disease	0,73	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	2,9	0,57	0,8	47,06	9,43	P	0,56	P	0,97	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11868	11868	C	G	MI.18658	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1109	370	P	R	cCc/cGc	4,4	0,99	0	probably_damaging	1	deleterious	0	neutral	3,53	deleterious	-7,34	deleterious	-8,4	high_impact	4,62	neutral	0,61	damaging	0,08	deleterious	3,69	23,3	0,03	0,35	disease	0,77	disease	0,87	disease	0,84	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,45	0,26	0,8	47,06	9,43	P	0,62	P	0,58	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11870	11870	C	T	MI.18659	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1111	371	P	S	Ccc/Tcc	-8,26	0	0	probably_damaging	1	deleterious	0	neutral	4,34	deleterious	-4,42	deleterious	-7,47	high_impact	3,81	neutral	0,61	neutral	0,51	deleterious	4,01	23,6	0,13	0,4	disease	0,89	disease	0,79	disease	0,73	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	2,64	0,12	0,8	45,97	9,16	N	0,34	N	0,71	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8565	8565	A	T	MI.1866	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	200	67	Q	L	cAa/cTa	0,59	0	0	benign	0,01	neutral	0,65	neutral	1,66	neutral	-2,51	deleterious	-3,84	medium_impact	1,99	neutral	0,98	neutral	0,38	deleterious	1,93	15,74	0,67403744	0,85	disease	0,56	neutral	0,07	neutral	0,48	neutral	0,05	9	neutral	0,33	deleterious	0,82	neutral	-3	neutral	0,19	medium_impact	1,14	medium_impact	0,44	medium_impact	0,61	0,46	0,85	NA	NA	N	0,37	N	0,77	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11870	11870	C	G	MI.18660	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1111	371	P	A	Ccc/Gcc	-8,26	0	0	probably_damaging	1	deleterious	0	neutral	4,36	deleterious	-3,57	deleterious	-7,47	high_impact	3,96	damaging	0,52	neutral	0,48	deleterious	3,21	22,7	0,14	0,4	disease	0,84	disease	0,6	disease	0,73	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	2,79	0,54	0,8	45,97	9,16	N	0,37	N	0,77	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11870	11870	C	A	MI.18661	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1111	371	P	T	Ccc/Acc	-8,26	0	0	probably_damaging	1	deleterious	0,01	neutral	4,35	deleterious	-4,15	deleterious	-7,47	high_impact	3,7	neutral	0,61	neutral	0,41	deleterious	3,8	23,4	0,12	0,4	disease	0,68	disease	0,76	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-3,54	medium_impact	-0,92	high_impact	2,53	0,43	0,8	45,97	9,16	N	0,32	N	0,89	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11871	11871	C	A	MI.18662	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1112	371	P	H	cCc/cAc	7,17	1	0	probably_damaging	1	deleterious	0	neutral	4,31	deleterious	-5,8	deleterious	-8,4	high_impact	4,5	damaging	0,54	neutral	0,35	deleterious	4,13	23,8	0,07	0,35	disease	0,95	disease	0,84	disease	0,8	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,24	0,8	45,97	9,16	P	0,61	P	0,7	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11871	11871	C	T	MI.18663	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1112	371	P	L	cCc/cTc	7,17	1	0	probably_damaging	1	neutral	0,09	neutral	4,46	neutral	-1,93	deleterious	-9,33	medium_impact	2,79	damaging	0,54	neutral	0,44	deleterious	4,51	24,3	0,11	0,4	disease	0,88	disease	0,85	disease	0,69	disease	0,77	5	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,85	low_impact	-3,54	medium_impact	-0,36	medium_impact	1,63	0,72	0,85	45,97	9,16	P	0,63	P	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11871	11871	C	G	MI.18664	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1112	371	P	R	cCc/cGc	7,17	1	0	probably_damaging	1	deleterious	0	neutral	4,32	deleterious	-5,35	deleterious	-8,4	high_impact	4,5	damaging	0,58	neutral	0,41	deleterious	3,7	23,3	0,05	0,35	disease	0,88	disease	0,85	disease	0,82	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,33	0,27	0,8	45,97	9,16	P	0,64	P	0,58	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11873	11873	A	C	MI.18665	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1114	372	T	P	Act/Cct	-8,26	0	0	probably_damaging	0,96	deleterious	0,02	neutral	4,42	deleterious	-4,87	deleterious	-3,8	high_impact	3,92	neutral	0,72	neutral	0,33	deleterious	3,58	23,2	0,04	0,35	disease	0,8	disease	0,82	disease	0,58	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,8	low_impact	-2,01	medium_impact	-0,75	high_impact	2,75	0,3	0,8	14,38	17,44	N	0,37	N	0,97	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11873	11873	A	G	MI.18666	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1114	372	T	A	Act/Gct	-8,26	0	0	possibly_damaging	0,64	neutral	0,08	neutral	4,47	neutral	-2,26	neutral	-2,38	medium_impact	2,94	neutral	0,77	neutral	0,65	deleterious	2,5	19,44	0,21	0,45	neutral	0,41	neutral	0,4	disease	0,52	neutral	0,49	0	neutral	0,92	neutral	0,22	NA	0	deleterious	0,68	medium_impact	-0,95	medium_impact	-0,39	medium_impact	1,78	0,33	0,8	14,38	17,44	N	0,45	N	0,66	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11873	11873	A	T	MI.18667	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1114	372	T	S	Act/Tct	-8,26	0	0	benign	0,13	neutral	1	neutral	4,5	neutral	-2,42	neutral	-1,2	neutral_impact	0,15	neutral	0,77	neutral	0,99	deleterious	1,84	15,22	0,34	0,5	neutral	0,48	neutral	0,12	neutral	0,22	neutral	0,3	4	neutral	0,13	deleterious	0,94	neutral	-6	deleterious	0,67	medium_impact	0,06	high_impact	1,88	medium_impact	-0,98	0,52	0,8	14,38	17,44	N	0,27	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11874	11874	C	G	MI.18668	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1115	372	T	S	aCt/aGt	-0,66	0	0	benign	0,13	neutral	1	neutral	4,5	neutral	-2,42	neutral	-1,2	neutral_impact	0,15	neutral	0,77	neutral	0,99	deleterious	1,95	15,91	0,34	0,5	neutral	0,48	neutral	0,12	neutral	0,22	neutral	0,3	4	neutral	0,13	deleterious	0,94	neutral	-6	deleterious	0,67	medium_impact	0,06	high_impact	1,88	medium_impact	-0,98	0,52	0,8	14,38	17,44	N	0,28	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11874	11874	C	T	MI.18669	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1115	372	T	I	aCt/aTt	-0,66	0	0	probably_damaging	0,96	deleterious	0,04	neutral	4,48	neutral	-2,23	deleterious	-3,37	high_impact	3,92	neutral	0,73	neutral	0,53	deleterious	2,57	19,95	0,11	0,4	disease	0,83	disease	0,65	neutral	0,41	disease	0,54	1	deleterious	0,99	neutral	0,04	deleterious	6	deleterious	0,76	low_impact	-2,01	medium_impact	-0,57	high_impact	2,75	0,6	0,8	14,38	17,44	N	0,48	N	0,8	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8565	8565	A	C	MI.1867	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	200	67	Q	P	cAa/cCa	0,59	0	0	benign	0,06	neutral	0,2	neutral	1,64	deleterious	-3,52	deleterious	-3,71	low_impact	1,86	neutral	0,97	damaging	0,24	neutral	1,54	13,54	0,5726291	0,85	disease	0,68	neutral	0,12	neutral	0,49	neutral	0,21	6	neutral	0,78	deleterious	0,57	neutral	-6	neutral	0,23	medium_impact	0,38	medium_impact	-0,05	medium_impact	0,5	0,67	0,85	NA	NA	N	0,49	N	0,72	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11874	11874	C	A	MI.18670	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1115	372	T	N	aCt/aAt	-0,66	0	0	possibly_damaging	0,83	deleterious	0,04	neutral	4,42	deleterious	-4,61	deleterious	-2,74	high_impact	3,92	neutral	0,71	neutral	0,48	deleterious	3,62	23,2	0,23	0,45	neutral	0,47	disease	0,65	disease	0,63	disease	0,7	4	neutral	0,98	neutral	0,11	deleterious	5	deleterious	0,71	low_impact	-1,37	medium_impact	-0,57	high_impact	2,75	0,48	0,8	14,38	17,44	P	0,54	P	0,66	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	C11874A	LHON	+	-	Reported	1
chrM	11876	11876	A	C	MI.18671	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1117	373	I	L	Att/Ctt	-10,1	0	0	probably_damaging	1	neutral	1	neutral	4,89	neutral	0,49	neutral	-1,25	low_impact	1,08	neutral	0,63	damaging	0,1	neutral	1,14	11,45	0,21	0,45	neutral	0,48	neutral	0,41	neutral	0,23	neutral	0,43	1	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,64	low_impact	-3,54	high_impact	1,88	medium_impact	-0,06	0,68	0,85	45,75	8,67	N	0,21	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11876	11876	A	G	MI.18672	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1117	373	I	V	Att/Gtt	-10,1	0	0	probably_damaging	1	neutral	0,29	neutral	4,66	neutral	0,6	neutral	-0,43	medium_impact	2	damaging	0,51	damaging	0,21	neutral	1,66	14,17	0,41	0,5	neutral	0,38	neutral	0,31	neutral	0,28	neutral	0,47	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,62	low_impact	-3,54	medium_impact	-0,02	medium_impact	0,85	0,34	0,8	45,75	8,67	N	0,47	N	0,75	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11876	11876	A	T	MI.18673	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1117	373	I	F	Att/Ttt	-10,1	0	0	probably_damaging	1	neutral	0,07	neutral	4,65	neutral	-0,79	deleterious	-2,92	medium_impact	2,73	damaging	0,46	damaging	0,05	deleterious	2,85	21,6	0,17	0,45	disease	0,67	disease	0,69	disease	0,51	disease	0,53	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,43	medium_impact	1,58	0,61	0,8	45,75	8,67	N	0,33	N	0,96	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11877	11877	T	C	MI.18674	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1118	373	I	T	aTt/aCt	4,86	0,95	0	probably_damaging	1	neutral	0,19	neutral	4,7	neutral	-0,54	deleterious	-2,66	low_impact	1,58	neutral	0,6	damaging	0,18	deleterious	2,24	17,79	0,1	0,4	neutral	0,43	neutral	0,43	neutral	0,34	neutral	0,46	1	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,68	low_impact	-3,54	medium_impact	-0,15	medium_impact	0,44	0,21	0,8	45,75	8,67	P	0,53	P	0,96	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11877	11877	T	G	MI.18675	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1118	373	I	S	aTt/aGt	4,86	0,95	0	probably_damaging	1	deleterious	0,04	neutral	4,74	neutral	1,72	deleterious	-3,52	low_impact	1,82	damaging	0,4	damaging	0,09	deleterious	4,29	24	0,04	0,35	neutral	0,44	disease	0,77	disease	0,54	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,73	low_impact	-3,54	medium_impact	-0,57	medium_impact	0,68	0,17	0,8	45,75	8,67	P	0,63	P	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11877	11877	T	A	MI.18676	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1118	373	I	N	aTt/aAt	4,86	0,95	0	probably_damaging	1	deleterious	0,01	neutral	4,58	neutral	0,84	deleterious	-4,45	medium_impact	2,41	damaging	0,38	damaging	0,06	deleterious	4,43	24,2	0,09	0,35	disease	0,83	disease	0,79	disease	0,61	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-3,54	medium_impact	-0,92	medium_impact	1,26	0,13	0,8	45,75	8,67	P	0,66	P	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11878	11878	T	A	MI.18677	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1119	373	I	M	atT/atA	2,1	0,93	0	probably_damaging	1	neutral	0,25	neutral	4,63	neutral	-1,52	neutral	-1,75	low_impact	1,64	damaging	0,58	damaging	0,19	deleterious	2,33	18,4	0,25	0,45	disease	0,72	neutral	0,42	neutral	0,26	disease	0,64	3	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,73	low_impact	-3,54	medium_impact	-0,07	medium_impact	0,5	0,63	0,8	45,75	8,67	N	0,41	N	0,76	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11878	11878	T	G	MI.18678	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1119	373	I	M	atT/atG	2,1	0,93	0	probably_damaging	1	neutral	0,25	neutral	4,63	neutral	-1,52	neutral	-1,75	low_impact	1,64	damaging	0,58	damaging	0,19	deleterious	2,09	16,82	0,25	0,45	disease	0,72	neutral	0,42	neutral	0,26	disease	0,64	3	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,73	low_impact	-3,54	medium_impact	-0,07	medium_impact	0,5	0,63	0,8	45,75	8,67	N	0,42	N	0,76	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11879	11879	A	G	MI.18679	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1120	374	N	D	Aac/Gac	-8,95	0	0	probably_damaging	1	deleterious	0	neutral	4,55	neutral	-1,7	deleterious	-4,66	high_impact	4,53	neutral	0,69	damaging	0,14	deleterious	3,97	23,6	0,32	0,5	disease	0,85	disease	0,8	disease	0,79	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,36	0,39	0,8	47,93	9,12	N	0,51	P	0,96	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8566	8566	A	C	MI.1868	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	201	67	Q	H	caA/caC	-0,8	0	0,01	benign	0,12	neutral	0,55	neutral	1,65	deleterious	-3,09	neutral	-2,14	low_impact	1,49	neutral	1	neutral	0,87	deleterious	0,32	5,85	0,79340444	0,85	disease	0,6	neutral	0,03	neutral	0,42	neutral	0,04	9	neutral	0,36	deleterious	0,72	neutral	-6	neutral	0,23	medium_impact	0,07	medium_impact	0,34	medium_impact	0,18	0,72	0,85	NA	NA	N	0,4	N	0,39	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11879	11879	A	T	MI.18680	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1120	374	N	Y	Aac/Tac	-8,95	0	0	probably_damaging	1	deleterious	0	neutral	4,55	neutral	-2,04	deleterious	-7,46	high_impact	4,17	neutral	0,65	damaging	0,12	deleterious	3,8	23,4	0,05	0,35	disease	0,5	disease	0,88	disease	0,76	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,54	low_impact	-1,48	high_impact	3	0,23	0,8	47,93	9,12	N	0,42	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11879	11879	A	C	MI.18681	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1120	374	N	H	Aac/Cac	-8,95	0	0	probably_damaging	1	deleterious	0	neutral	4,53	neutral	-2,31	deleterious	-4,66	high_impact	4,17	neutral	0,63	damaging	0,11	deleterious	3,21	22,7	0,21	0,45	disease	0,5	disease	0,85	disease	0,8	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	3	0,28	0,8	47,93	9,12	N	0,44	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11880	11880	A	T	MI.18682	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1121	374	N	I	aAc/aTc	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,54	neutral	-0,58	deleterious	-8,4	high_impact	4,17	neutral	0,63	damaging	0,15	deleterious	4,03	23,6	0,06	0,35	neutral	0,48	disease	0,9	disease	0,72	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,54	low_impact	-1,48	high_impact	3	0,12	0,8	47,93	9,12	P	0,63	P	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11880	11880	A	C	MI.18683	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1121	374	N	T	aAc/aCc	8,55	1	0	probably_damaging	1	deleterious	0,02	neutral	4,56	neutral	-0,45	deleterious	-5,59	high_impact	3,55	neutral	0,68	damaging	0,14	deleterious	3,5	23,1	0,17	0,45	disease	0,54	disease	0,83	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,54	medium_impact	-0,75	high_impact	2,39	0,38	0,8	47,93	9,12	P	0,58	P	0,95	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11880	11880	A	G	MI.18684	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1121	374	N	S	aAc/aGc	8,55	1	0	probably_damaging	1	neutral	0,16	neutral	4,64	neutral	-0,22	deleterious	-4,66	medium_impact	2,55	neutral	0,63	damaging	0,19	deleterious	3,22	22,7	0,39	0,5	disease	0,65	disease	0,81	disease	0,63	disease	0,61	2	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,2	medium_impact	1,4	0,32	0,8	47,93	9,12	P	0,6	P	0,85	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11881	11881	C	A	MI.18685	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1122	374	N	K	aaC/aaA	6,7	1	0	probably_damaging	1	deleterious	0	neutral	4,61	neutral	-0,82	deleterious	-5,59	high_impact	4,53	damaging	0,58	damaging	0,15	deleterious	4,6	24,4	0,21	0,45	disease	0,74	disease	0,88	disease	0,78	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,36	0,5	0,8	47,93	9,12	P	0,66	P	0,99	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11881	11881	C	G	MI.18686	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1122	374	N	K	aaC/aaG	6,7	1	0	probably_damaging	1	deleterious	0	neutral	4,61	neutral	-0,82	deleterious	-5,59	high_impact	4,53	damaging	0,58	damaging	0,15	deleterious	4,13	23,8	0,21	0,45	disease	0,74	disease	0,88	disease	0,78	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,36	0,5	0,8	47,93	9,12	P	0,66	P	0,99	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11882	11882	C	A	MI.18687	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1123	375	L	M	Cta/Ata	-4,81	0	0	probably_damaging	1	neutral	0,06	neutral	4,51	deleterious	-3,11	neutral	-1,74	medium_impact	2,42	neutral	0,69	damaging	0,19	deleterious	4,06	23,7	0,2	0,45	disease	0,51	disease	0,52	neutral	0,38	neutral	0,46	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,27	0,49	0,8	45,53	8,73	N	0,36	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11882	11882	C	G	MI.18688	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1123	375	L	V	Cta/Gta	-4,81	0	0	probably_damaging	1	deleterious	0,02	neutral	4,53	neutral	-2	deleterious	-2,71	high_impact	4,29	neutral	0,65	damaging	0,13	deleterious	3,54	23,1	0,2	0,45	neutral	0,38	disease	0,54	disease	0,58	disease	0,62	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,75	low_impact	-3,54	medium_impact	-0,75	high_impact	3,12	0,58	0,8	45,53	8,73	N	0,42	N	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11883	11883	T	G	MI.18689	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1124	375	L	R	cTa/cGa	-1,35	0	0	probably_damaging	1	deleterious	0	neutral	4,51	deleterious	-3,72	deleterious	-5,47	high_impact	4,29	neutral	0,67	damaging	0,11	deleterious	4,34	24	0,02	0,35	disease	0,69	disease	0,84	disease	0,73	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,12	0,11	0,8	45,53	8,73	N	0,38	N	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8566	8566	A	T	MI.1869	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	201	67	Q	H	caA/caT	-0,8	0	0,01	benign	0,12	neutral	0,55	neutral	1,65	deleterious	-3,09	neutral	-2,14	low_impact	1,49	neutral	1	neutral	0,87	deleterious	1,93	15,79	0,79340444	0,85	disease	0,6	neutral	0,03	neutral	0,42	neutral	0,04	9	neutral	0,36	deleterious	0,72	neutral	-6	neutral	0,23	medium_impact	0,07	medium_impact	0,34	medium_impact	0,18	0,72	0,85	NA	NA	N	0,41	N	0,39	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11883	11883	T	A	MI.18690	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1124	375	L	Q	cTa/cAa	-1,35	0	0	probably_damaging	1	deleterious	0	neutral	4,51	deleterious	-3,72	deleterious	-5,46	high_impact	4,29	neutral	0,63	damaging	0,12	deleterious	4,23	23,9	0,03	0,35	disease	0,69	disease	0,81	disease	0,6	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,12	0,33	0,8	45,53	8,73	N	0,35	N	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11883	11883	T	C	MI.18691	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1124	375	L	P	cTa/cCa	-1,35	0	0	probably_damaging	1	deleterious	0	neutral	4,5	deleterious	-4,4	deleterious	-6,41	high_impact	3,94	neutral	0,61	damaging	0,12	deleterious	4,03	23,7	0,02	0,35	disease	0,76	disease	0,81	disease	0,73	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	2,77	0,17	0,8	45,53	8,73	N	0,32	N	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11885	11885	C	A	MI.18692	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1126	376	L	M	Ctg/Atg	-7,57	0	0	benign	0,12	neutral	1	neutral	4,46	neutral	-1,72	neutral	0,44	neutral_impact	0,45	neutral	0,7	neutral	0,94	neutral	1,2	11,75	0,31	0,45	neutral	0,19	neutral	0,03	neutral	0,15	neutral	0,22	6	neutral	0,12	deleterious	0,94	neutral	-6	deleterious	0,64	medium_impact	0,1	high_impact	1,88	medium_impact	-0,68	0,52	0,8	25,93	16,52	N	0,39	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11885	11885	C	G	MI.18693	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1126	376	L	V	Ctg/Gtg	-7,57	0	0	benign	0,03	neutral	0,42	neutral	4,62	neutral	0,71	neutral	-0,4	neutral_impact	0,79	neutral	0,8	neutral	0,97	deleterious	2,34	18,43	0,27	0,45	neutral	0,28	neutral	0,27	neutral	0,25	neutral	0,45	1	neutral	0,56	deleterious	0,7	neutral	-6	deleterious	0,68	medium_impact	0,7	medium_impact	0,12	medium_impact	-0,34	0,49	0,8	25,93	16,52	N	0,4	N	0,14	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11886	11886	T	A	MI.18694	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1127	376	L	Q	cTg/cAg	0,95	0,1	0	possibly_damaging	0,87	deleterious	0	neutral	4,4	deleterious	-3,13	deleterious	-3,44	medium_impact	3,44	neutral	0,68	neutral	0,59	deleterious	4,31	24	0,05	0,35	disease	0,66	disease	0,59	disease	0,58	disease	0,68	4	deleterious	1	neutral	0,07	deleterious	4	deleterious	0,8	low_impact	-1,49	low_impact	-1,48	high_impact	2,28	0,2	0,8	25,93	16,52	N	0,45	N	0,73	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11886	11886	T	C	MI.18695	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1127	376	L	P	cTg/cCg	0,95	0,1	0	probably_damaging	0,93	deleterious	0	neutral	4,4	deleterious	-3,14	deleterious	-4,37	medium_impact	2,64	damaging	0,57	neutral	0,44	deleterious	4,07	23,7	0,04	0,35	disease	0,72	disease	0,81	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,88	low_impact	-1,77	low_impact	-1,48	medium_impact	1,49	0,17	0,8	25,93	16,52	N	0,35	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11886	11886	T	G	MI.18696	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1127	376	L	R	cTg/cGg	0,95	0,1	0	possibly_damaging	0,87	deleterious	0	neutral	4,4	deleterious	-3,47	deleterious	-3,86	medium_impact	3,44	neutral	0,65	neutral	0,51	deleterious	4,29	24	0,03	0,35	disease	0,64	disease	0,77	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,07	deleterious	4	deleterious	0,85	low_impact	-1,49	low_impact	-1,48	high_impact	2,28	0,11	0,8	25,93	16,52	N	0,4	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11888	11888	G	C	MI.18697	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1129	377	G	R	Gga/Cga	-4,12	0	0	probably_damaging	1	deleterious	0	neutral	4,44	deleterious	-4,88	deleterious	-7,25	high_impact	4,34	neutral	0,68	neutral	0,29	deleterious	4,03	23,6	0,01	0,35	disease	0,65	disease	0,89	disease	0,74	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	3,17	0,36	0,8	45,75	8,66	N	0,41	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11888	11888	G	T	MI.18698	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1129	377	G	W	Gga/Tga	-4,12	0	0	probably_damaging	1	deleterious	0	neutral	4,41	deleterious	-7,41	deleterious	-7,31	high_impact	4,34	neutral	0,65	damaging	0,28	deleterious	4,54	24,3	0,02	0,35	disease	0,82	disease	0,89	disease	0,69	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	3,17	0,15	0,8	45,75	8,66	N	0,36	N	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11889	11889	G	C	MI.18699	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1130	377	G	A	gGa/gCa	7,17	1	0	probably_damaging	1	neutral	0,13	neutral	4,56	neutral	-1,33	deleterious	-5,34	low_impact	1,64	neutral	0,66	neutral	0,54	deleterious	3,23	22,8	0,1	0,4	neutral	0,34	neutral	0,49	neutral	0,36	neutral	0,43	2	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,76	low_impact	-3,54	medium_impact	-0,26	medium_impact	0,5	0,42	0,8	45,75	8,66	P	0,59	P	0,76	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8614	8614	T	A	MI.187	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	88	30	L	M	Ttg/Atg	-20	0	0,01	probably_damaging	1	neutral	0,1	neutral	4,22	neutral	-2,21	neutral	-1,35	low_impact	1,92	neutral	0,91	neutral	0,9	deleterious	2,26	17,92	0,32	0,65	disease	0,6	neutral	0,26	neutral	0,19	disease	0,54	1	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	-0,25	medium_impact	0,55	0,66	0,9	17,7	14,1	N	0,52	P	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8567	8567	T	A	MI.1870	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	202	68	S	T	Tcc/Acc	-4,27	0	0	possibly_damaging	0,85	neutral	0,4	neutral	1,7	neutral	-1,87	neutral	-0,6	low_impact	1,54	neutral	0,96	neutral	0,42	deleterious	4,28	24	0,39834806	0,85	NA	NA	neutral	0,05	disease	0,71	neutral	0,16	7	neutral	0,85	neutral	0,28	neutral	-3	deleterious	0,76	low_impact	-1,47	medium_impact	0,19	medium_impact	0,22	0,84	0,9	NA	NA	N	0,47	N	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11889	11889	G	A	MI.18700	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1130	377	G	E	gGa/gAa	7,17	1	0	probably_damaging	1	deleterious	0	neutral	4,46	deleterious	-4,34	deleterious	-7,23	high_impact	4,34	neutral	0,67	neutral	0,36	deleterious	4	23,6	0,02	0,35	disease	0,66	disease	0,88	disease	0,73	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,17	0,17	0,8	45,75	8,66	P	0,62	P	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11889	11889	G	T	MI.18701	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1130	377	G	V	gGa/gTa	7,17	1	0	probably_damaging	1	deleterious	0,01	neutral	4,47	deleterious	-4,48	deleterious	-8,15	high_impact	4	neutral	0,67	neutral	0,41	deleterious	3,98	23,6	0,02	0,35	neutral	0,22	disease	0,86	disease	0,65	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-3,54	medium_impact	-0,92	high_impact	2,83	0,13	0,8	45,75	8,66	P	0,57	P	0,98	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11891	11891	G	A	MI.18702	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1132	378	E	K	Gaa/Aaa	-1,12	0	0	probably_damaging	1	deleterious	0,01	neutral	5,16	neutral	1,64	deleterious	-3,73	high_impact	4,64	damaging	0,33	damaging	0,07	deleterious	4,61	24,4	0,13	0,4	disease	0,79	disease	0,83	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,54	medium_impact	-0,92	high_impact	3,46	0,73	0,85	47,06	9,14	P	0,67	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11891	11891	G	C	MI.18703	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1132	378	E	Q	Gaa/Caa	-1,12	0	0	probably_damaging	1	deleterious	0	neutral	4,36	neutral	-2,89	deleterious	-2,8	high_impact	4,64	damaging	0,36	damaging	0,07	deleterious	3,53	23,1	0,14	0,4	disease	0,81	disease	0,73	disease	0,72	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,46	0,39	0,8	47,06	9,14	P	0,63	P	0,92	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11892	11892	A	G	MI.18704	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1133	378	E	G	gAa/gGa	7,17	1	0	probably_damaging	1	deleterious	0	neutral	4,34	deleterious	-3,84	deleterious	-6,54	high_impact	4,3	damaging	0,36	damaging	0,12	deleterious	4,33	24	0,07	0,35	disease	0,87	disease	0,7	disease	0,73	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	3,13	0,14	0,8	47,06	9,14	P	0,78	P	0,53	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11892	11892	A	T	MI.18705	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1133	378	E	V	gAa/gTa	7,17	1	0	probably_damaging	1	deleterious	0	neutral	4,33	deleterious	-4,37	deleterious	-6,54	high_impact	4,64	damaging	0,35	damaging	0,08	deleterious	4,2	23,9	0,05	0,35	disease	0,86	disease	0,83	disease	0,73	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	3,46	0,26	0,8	47,06	9,14	P	0,77	P	0,8	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11892	11892	A	C	MI.18706	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1133	378	E	A	gAa/gCa	7,17	1	0	probably_damaging	1	deleterious	0	neutral	4,36	deleterious	-3,07	deleterious	-5,6	high_impact	4,64	damaging	0,39	damaging	0,13	deleterious	3,74	23,3	0,07	0,35	disease	0,68	disease	0,66	disease	0,71	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,46	0,32	0,8	47,06	9,14	P	0,8	P	0,74	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11893	11893	A	C	MI.18707	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1134	378	E	D	gaA/gaC	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,37	neutral	-2,73	deleterious	-2,8	high_impact	4,64	damaging	0,33	damaging	0,07	deleterious	3,79	23,4	0,15	0,4	disease	0,87	disease	0,68	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,46	0,4	0,8	47,06	9,14	P	0,79	P	0,89	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11893	11893	A	T	MI.18708	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1134	378	E	D	gaA/gaT	8,55	1	0	probably_damaging	1	deleterious	0	neutral	4,37	neutral	-2,73	deleterious	-2,8	high_impact	4,64	damaging	0,33	damaging	0,07	deleterious	3,89	23,5	0,15	0,4	disease	0,87	disease	0,68	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	3,46	0,4	0,8	47,06	9,14	P	0,79	P	0,89	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11894	11894	C	A	MI.18709	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1135	379	L	I	Ctc/Atc	0,49	0,03	0	probably_damaging	1	neutral	0,82	neutral	4,58	neutral	-1,29	neutral	-1,65	low_impact	1	neutral	0,77	neutral	0,39	deleterious	3,21	22,7	0,3	0,45	disease	0,7	neutral	0,15	neutral	0,19	neutral	0,38	2	deleterious	1	neutral	0,41	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	0,57	medium_impact	-0,14	0,56	0,8	47,49	8,78	N	0,27	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8567	8567	T	G	MI.1871	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	202	68	S	A	Tcc/Gcc	-4,27	0	0	possibly_damaging	0,78	neutral	0,52	neutral	1,76	neutral	-1,14	neutral	-0,75	low_impact	1,54	neutral	1	damaging	0,21	deleterious	3,68	23,3	0,4839256	0,85	NA	NA	neutral	0,04	disease	0,66	neutral	0,16	7	neutral	0,75	neutral	0,37	neutral	-3	deleterious	0,63	low_impact	-1,28	medium_impact	0,31	medium_impact	0,22	0,75	0,85	NA	NA	N	0,43	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11894	11894	C	T	MI.18710	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1135	379	L	F	Ctc/Ttc	0,49	0,03	0	probably_damaging	1	neutral	0,29	neutral	4,67	neutral	0,59	deleterious	-3,42	low_impact	1,77	neutral	0,69	damaging	0,17	deleterious	4,04	23,7	0,24	0,45	disease	0,82	disease	0,59	neutral	0,4	disease	0,53	1	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,78	low_impact	-3,54	medium_impact	-0,02	medium_impact	0,63	0,45	0,8	47,49	8,78	N	0,3	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11894	11894	C	G	MI.18711	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1135	379	L	V	Ctc/Gtc	0,49	0,03	0	probably_damaging	1	neutral	0,19	neutral	4,56	neutral	-1,31	deleterious	-2,54	medium_impact	2,12	neutral	0,72	damaging	0,2	deleterious	3,52	23,1	0,29	0,45	disease	0,66	neutral	0,45	neutral	0,41	disease	0,6	2	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	-0,15	medium_impact	0,97	0,61	0,8	47,49	8,78	N	0,39	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11895	11895	T	C	MI.18712	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1136	379	L	P	cTc/cCc	-2,04	0	0	probably_damaging	1	deleterious	0	neutral	4,46	deleterious	-4,53	deleterious	-6,3	high_impact	4,07	damaging	0,59	damaging	0,13	deleterious	4,09	23,7	0,02	0,35	disease	0,88	disease	0,8	disease	0,69	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	2,9	0,15	0,8	47,49	8,78	N	0,29	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11895	11895	T	A	MI.18713	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1136	379	L	H	cTc/cAc	-2,04	0	0	probably_damaging	1	deleterious	0	neutral	4,48	deleterious	-4,03	deleterious	-6,25	high_impact	4,07	neutral	0,68	damaging	0,11	deleterious	4,47	24,2	0,04	0,35	disease	0,74	disease	0,77	disease	0,64	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	2,9	0,17	0,8	47,49	8,78	N	0,29	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11895	11895	T	G	MI.18714	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1136	379	L	R	cTc/cGc	-2,04	0	0	probably_damaging	1	deleterious	0	neutral	4,47	deleterious	-3,61	deleterious	-5,4	high_impact	4,07	damaging	0,58	damaging	0,12	deleterious	4,34	24,1	0,02	0,35	disease	0,75	disease	0,82	disease	0,68	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	2,9	0,08	0,8	47,49	8,78	N	0,29	N	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11897	11897	T	C	MI.18715	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1138	380	S	P	Tct/Cct	-0,43	0	0	possibly_damaging	0,45	deleterious	0,03	neutral	4,59	neutral	-1,53	neutral	-1,34	low_impact	1,92	neutral	0,61	neutral	0,45	deleterious	3,66	23,2	0,05	0,35	disease	0,69	disease	0,7	disease	0,56	disease	0,7	4	neutral	0,97	neutral	0,29	deleterious	1	deleterious	0,56	medium_impact	-0,64	medium_impact	-0,64	medium_impact	0,77	0,3	0,8	23,97	19,12	N	0,35	N	0,7	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11897	11897	T	A	MI.18716	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1138	380	S	T	Tct/Act	-0,43	0	0	benign	0,1	neutral	0,37	neutral	4,65	neutral	0,11	neutral	0,62	neutral_impact	0,04	neutral	0,7	neutral	0,77	deleterious	0,46	7,15	0,28	0,45	neutral	0,5	neutral	0,07	neutral	0,11	neutral	0,21	6	neutral	0,58	deleterious	0,64	neutral	-6	neutral	0,28	medium_impact	0,18	medium_impact	0,07	low_impact	-1,09	0,48	0,8	23,97	19,12	P	0,56	P	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11897	11897	T	G	MI.18717	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1138	380	S	A	Tct/Gct	-0,43	0	0	benign	0,05	neutral	0,13	neutral	4,66	neutral	0,34	neutral	0,16	low_impact	1,46	neutral	0,74	neutral	0,86	deleterious	0,86	9,83	0,35	0,5	disease	0,53	neutral	0,17	neutral	0,3	neutral	0,31	4	neutral	0,86	deleterious	0,54	neutral	-6	neutral	0,19	medium_impact	0,48	medium_impact	-0,26	medium_impact	0,32	0,44	0,8	23,97	19,12	P	0,52	P	0,26	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11898	11898	C	T	MI.18718	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1139	380	S	F	tCt/tTt	-0,2	0	0	benign	0	neutral	0,71	neutral	4,65	neutral	0,05	neutral	2,01	neutral_impact	-0,39	neutral	0,8	neutral	0,96	deleterious	0,3	5,72	0,06	0,35	disease	0,64	neutral	0,34	neutral	0,2	disease	0,61	2	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,17	high_impact	2,1	medium_impact	0,42	low_impact	-1,51	0,12	0,8	23,97	19,12	N	0,24	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11898	11898	C	G	MI.18719	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1139	380	S	C	tCt/tGt	-0,2	0	0	possibly_damaging	0,76	deleterious	0,03	neutral	4,58	neutral	-2,32	neutral	-0,09	low_impact	1,72	neutral	0,73	neutral	0,42	deleterious	3,48	23,1	0,07	0,35	disease	0,92	neutral	0,49	neutral	0,4	disease	0,69	4	neutral	0,98	neutral	0,14	deleterious	1	deleterious	0,65	low_impact	-1,19	medium_impact	-0,64	medium_impact	0,58	0,23	0,8	23,97	19,12	N	0,45	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8567	8567	T	C	MI.1872	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	202	68	S	P	Tcc/Ccc	-4,27	0	0	probably_damaging	0,94	neutral	0,21	neutral	1,64	deleterious	-3,23	neutral	-1,25	low_impact	1,54	neutral	0,99	damaging	0,11	deleterious	4,14	23,8	0,52918828	0,85	NA	NA	neutral	0,1	disease	0,69	neutral	0,19	6	neutral	0,96	neutral	0,14	neutral	-2	deleterious	0,82	low_impact	-1,89	medium_impact	-0,03	medium_impact	0,22	0,55	0,85	NA	NA	N	0,47	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11898	11898	C	A	MI.18720	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1139	380	S	Y	tCt/tAt	-0,2	0	0	benign	0,11	neutral	0,23	neutral	4,72	neutral	0,99	neutral	0,91	low_impact	1,2	neutral	0,77	neutral	0,67	deleterious	2,2	17,5	0,06	0,35	disease	0,83	neutral	0,44	neutral	0,24	disease	0,66	3	neutral	0,74	deleterious	0,56	neutral	-6	neutral	0,28	medium_impact	0,14	medium_impact	-0,09	medium_impact	0,06	0,21	0,8	23,97	19,12	N	0,38	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11900	11900	G	A	MI.18721	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1141	381	V	M	Gtg/Atg	-9,18	0	0	probably_damaging	0,95	neutral	0,09	neutral	4,37	neutral	-2,6	neutral	-2,01	low_impact	0,99	neutral	0,75	neutral	0,54	deleterious	3,84	23,4	0,13	0,4	disease	0,75	disease	0,58	neutral	0,33	disease	0,5	0	deleterious	0,98	neutral	0,07	neutral	-2	deleterious	0,76	low_impact	-1,92	medium_impact	-0,36	medium_impact	-0,15	0,89	0,9	27,02	19,58	N	0,34	N	0,49	polymorphism	1	0,02	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	11900	11900	G	C	MI.18722	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1141	381	V	L	Gtg/Ctg	-9,18	0	0	possibly_damaging	0,49	neutral	0,66	neutral	4,63	neutral	-0,53	neutral	-1,38	neutral_impact	0,27	neutral	0,72	neutral	0,68	deleterious	3,79	23,4	0,16	0,45	disease	0,51	neutral	0,44	neutral	0,19	neutral	0,35	3	neutral	0,41	deleterious	0,59	neutral	-3	deleterious	0,71	medium_impact	-0,7	medium_impact	0,36	medium_impact	-0,86	0,52	0,8	27,02	19,58	N	0,35	N	0,56	polymorphism	1	0,02	rs878983346	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11900	11900	G	T	MI.18723	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1141	381	V	L	Gtg/Ttg	-9,18	0	0	possibly_damaging	0,49	neutral	0,66	neutral	4,63	neutral	-0,53	neutral	-1,38	neutral_impact	0,27	neutral	0,72	neutral	0,68	deleterious	3,89	23,5	0,16	0,45	disease	0,51	neutral	0,44	neutral	0,19	neutral	0,35	3	neutral	0,41	deleterious	0,59	neutral	-3	deleterious	0,71	medium_impact	-0,7	medium_impact	0,36	medium_impact	-0,86	0,52	0,8	27,02	19,58	N	0,35	N	0,56	polymorphism	1	0,02	rs878983346	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11901	11901	T	C	MI.18724	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1142	381	V	A	gTg/gCg	1,18	0,75	0	possibly_damaging	0,62	neutral	0,08	neutral	4,41	neutral	-1,81	deleterious	-3,43	low_impact	1	neutral	0,67	neutral	0,75	deleterious	3,63	23,2	0,06	0,35	neutral	0,48	disease	0,51	neutral	0,29	neutral	0,46	1	neutral	0,92	neutral	0,23	neutral	-3	deleterious	0,73	medium_impact	-0,92	medium_impact	-0,39	medium_impact	-0,14	0,17	0,8	27,02	19,58	N	0,4	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11901	11901	T	G	MI.18725	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1142	381	V	G	gTg/gGg	1,18	0,75	0	possibly_damaging	0,9	deleterious	0	neutral	4,34	deleterious	-4,19	deleterious	-6,14	medium_impact	2,6	neutral	0,7	neutral	0,46	deleterious	3,89	23,5	0,02	0,35	disease	0,73	disease	0,73	disease	0,51	disease	0,58	2	deleterious	1	neutral	0,05	deleterious	4	deleterious	0,79	low_impact	-1,61	low_impact	-1,48	medium_impact	1,45	0,2	0,8	27,02	19,58	N	0,38	N	0,95	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11901	11901	T	A	MI.18726	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1142	381	V	E	gTg/gAg	1,18	0,75	0	probably_damaging	0,94	deleterious	0	neutral	4,34	deleterious	-4,69	deleterious	-5,21	medium_impact	2,94	neutral	0,68	neutral	0,44	deleterious	4,72	24,6	0,02	0,35	disease	0,66	disease	0,89	disease	0,61	disease	0,8	6	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,86	low_impact	-1,84	low_impact	-1,48	medium_impact	1,78	0,18	0,8	27,02	19,58	N	0,36	N	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11903	11903	C	A	MI.18727	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1144	382	L	M	Cta/Ata	-2,96	0	0	benign	0,12	neutral	0,42	neutral	3,64	deleterious	-4,5	neutral	-0,33	neutral_impact	-0,12	neutral	0,74	neutral	0,96	deleterious	2,5	19,47	0,23	0,45	disease	0,59	neutral	0,1	neutral	0,16	neutral	0,4	2	neutral	0,51	deleterious	0,65	neutral	-6	deleterious	0,67	medium_impact	0,1	medium_impact	0,12	low_impact	-1,25	0,55	0,8	23,53	17,78	N	0,42	N	0,39	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11903	11903	C	G	MI.18728	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1144	382	L	V	Cta/Gta	-2,96	0	0	benign	0,01	neutral	0,21	neutral	3,63	deleterious	-4,73	neutral	0,52	neutral_impact	0,4	neutral	0,83	neutral	0,97	deleterious	2,25	17,82	0,21	0,45	neutral	0,42	neutral	0,34	neutral	0,23	neutral	0,47	1	neutral	0,78	deleterious	0,6	neutral	-6	deleterious	0,66	medium_impact	1,16	medium_impact	-0,12	medium_impact	-0,73	0,54	0,8	23,53	17,78	N	0,43	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11904	11904	T	G	MI.18729	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1145	382	L	R	cTa/cGa	0,03	0	0	possibly_damaging	0,87	deleterious	0	neutral	3,58	deleterious	-8,2	deleterious	-4,09	medium_impact	2,87	neutral	0,67	neutral	0,5	deleterious	4,32	24	0,02	0,35	disease	0,76	disease	0,84	disease	0,66	disease	0,8	6	deleterious	1	neutral	0,07	deleterious	4	deleterious	0,83	low_impact	-1,49	low_impact	-1,48	medium_impact	1,71	0,15	0,8	23,53	17,78	N	0,34	N	0,75	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8568	8568	C	T	MI.1873	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	203	68	S	F	tCc/tTc	1,75	0,01	0	probably_damaging	0,97	neutral	0,7	neutral	1,63	deleterious	-3,57	neutral	-0,68	neutral_impact	-0,04	neutral	0,99	damaging	0,14	deleterious	4,34	24	0,56070775	0,85	NA	NA	neutral	0,07	disease	0,7	neutral	0,18	6	neutral	0,97	neutral	0,37	neutral	-2	deleterious	0,87	low_impact	-2,19	medium_impact	0,5	low_impact	-1,13	0,52	0,85	NA	NA	N	0,41	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11904	11904	T	A	MI.18730	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1145	382	L	Q	cTa/cAa	0,03	0	0	possibly_damaging	0,87	deleterious	0	neutral	3,58	deleterious	-8,01	deleterious	-3,85	medium_impact	2,52	neutral	0,69	neutral	0,59	deleterious	4,28	24	0,03	0,35	disease	0,7	disease	0,64	disease	0,53	disease	0,63	3	deleterious	1	neutral	0,07	deleterious	4	deleterious	0,76	low_impact	-1,49	low_impact	-1,48	medium_impact	1,37	0,27	0,8	23,53	17,78	N	0,4	N	0,68	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11904	11904	T	C	MI.18731	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1145	382	L	P	cTa/cCa	0,03	0	0	probably_damaging	0,93	deleterious	0	neutral	3,58	deleterious	-8,51	deleterious	-4,2	medium_impact	2,87	neutral	0,62	neutral	0,43	deleterious	4,04	23,7	0,02	0,35	disease	0,7	disease	0,87	disease	0,68	disease	0,81	6	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,79	low_impact	-1,77	low_impact	-1,48	medium_impact	1,71	0,28	0,8	23,53	17,78	N	0,34	N	0,85	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11906	11906	G	A	MI.18732	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1147	383	V	M	Gta/Ata	-7,57	0	0	benign	0,03	neutral	0,61	neutral	4,61	neutral	-0,49	neutral	0,08	neutral_impact	-0,06	neutral	0,76	neutral	0,93	deleterious	-0,05	2,15	0,29	0,45	disease	0,8	neutral	0,28	neutral	0,19	disease	0,59	2	neutral	0,34	deleterious	0,79	neutral	-6	neutral	0,19	medium_impact	0,7	medium_impact	0,31	low_impact	-1,19	0,96	1	26,58	19,2	N	0,32	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11906	11906	G	C	MI.18733	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1147	383	V	L	Gta/Cta	-7,57	0	0	benign	0,01	neutral	0,83	neutral	4,68	neutral	-1,04	neutral	-0,26	neutral_impact	-0,01	neutral	0,78	neutral	0,91	deleterious	0,48	7,31	0,2	0,45	disease	0,81	neutral	0,46	neutral	0,23	disease	0,65	3	neutral	0,15	deleterious	0,91	neutral	-6	neutral	0,23	medium_impact	1,16	medium_impact	0,59	low_impact	-1,14	0,64	0,8	26,58	19,2	N	0,24	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11906	11906	G	T	MI.18734	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1147	383	V	L	Gta/Tta	-7,57	0	0	benign	0,01	neutral	0,83	neutral	4,68	neutral	-1,04	neutral	-0,26	neutral_impact	-0,01	neutral	0,78	neutral	0,91	deleterious	0,64	8,46	0,2	0,45	disease	0,81	neutral	0,46	neutral	0,23	disease	0,65	3	neutral	0,15	deleterious	0,91	neutral	-6	neutral	0,23	medium_impact	1,16	medium_impact	0,59	low_impact	-1,14	0,64	0,8	26,58	19,2	N	0,24	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11907	11907	T	A	MI.18735	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1148	383	V	E	gTa/gAa	0,03	0	0	benign	0,34	neutral	0,2	neutral	4,75	deleterious	-3,98	neutral	-2,47	medium_impact	2,71	neutral	0,74	neutral	0,51	deleterious	3,01	22,3	0,05	0,35	disease	0,96	disease	0,83	disease	0,66	disease	0,83	7	neutral	0,76	neutral	0,43	neutral	-3	neutral	0,41	medium_impact	-0,45	medium_impact	-0,14	medium_impact	1,56	0,18	0,8	26,58	19,2	N	0,3	N	0,57	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11907	11907	T	C	MI.18736	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1148	383	V	A	gTa/gCa	0,03	0	0	benign	0,01	neutral	0,48	neutral	4,69	neutral	-1,47	neutral	-1,15	low_impact	1,12	neutral	0,73	neutral	0,85	deleterious	0,63	8,4	0,15	0,45	disease	0,77	neutral	0,36	neutral	0,4	disease	0,65	3	neutral	0,51	deleterious	0,74	neutral	-6	neutral	0,23	medium_impact	1,16	medium_impact	0,18	medium_impact	-0,02	0,25	0,8	26,58	19,2	N	0,35	N	0,24	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11907	11907	T	G	MI.18737	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1148	383	V	G	gTa/gGa	0,03	0	0	benign	0,18	neutral	0,32	neutral	4,62	neutral	0,67	deleterious	-3,29	low_impact	1,06	neutral	0,71	neutral	0,51	deleterious	2,05	16,55	0,05	0,35	disease	0,73	disease	0,6	disease	0,55	disease	0,7	4	neutral	0,62	deleterious	0,57	neutral	-6	neutral	0,31	medium_impact	-0,1	medium_impact	0,02	medium_impact	-0,08	0,16	0,8	26,58	19,2	N	0,3	N	0,63	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11909	11909	A	T	MI.18738	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1150	384	T	S	Acc/Tcc	-3,89	0	0	benign	0,02	neutral	1	neutral	2,42	neutral	-0,56	neutral	1,1	neutral_impact	-1,12	neutral	0,76	neutral	0,99	neutral	-1,19	0,01	0,32	0,5	disease	0,56	neutral	0,08	neutral	0,17	neutral	0,35	3	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,14	medium_impact	0,87	high_impact	1,88	low_impact	-2,23	0,74	0,85	16,99	18,59	N	0,38	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11909	11909	A	C	MI.18739	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1150	384	T	P	Acc/Ccc	-3,89	0	0	possibly_damaging	0,55	deleterious	0	neutral	2,24	deleterious	-4,57	neutral	-2,35	medium_impact	2,14	neutral	0,77	neutral	0,5	deleterious	1,83	15,14	0,04	0,35	disease	0,92	disease	0,88	disease	0,69	disease	0,86	7	deleterious	1	neutral	0,23	deleterious	4	deleterious	0,49	medium_impact	-0,8	low_impact	-1,48	medium_impact	0,99	0,37	0,8	16,99	18,59	N	0,28	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8568	8568	C	G	MI.1874	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	203	68	S	C	tCc/tGc	1,75	0,01	0	probably_damaging	0,98	neutral	0,18	neutral	1,62	deleterious	-4,03	neutral	-1,25	low_impact	1,54	neutral	0,98	damaging	0,11	deleterious	3,74	23,3	0,57564883	0,85	NA	NA	neutral	0,05	disease	0,68	neutral	0,16	7	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,88	low_impact	-2,36	medium_impact	-0,08	medium_impact	0,22	0,63	0,85	NA	NA	N	0,49	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11909	11909	A	G	MI.18740	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1150	384	T	A	Acc/Gcc	-3,89	0	0	benign	0,01	neutral	0,3	neutral	2,49	neutral	-2,16	neutral	-0,05	neutral_impact	-0,82	neutral	0,8	neutral	0,98	deleterious	-0,06	2,08	0,22	0,45	disease	0,58	neutral	0,25	neutral	0,25	disease	0,55	1	neutral	0,7	deleterious	0,65	neutral	-6	neutral	0,16	medium_impact	1,16	medium_impact	0	low_impact	-1,94	0,33	0,8	16,99	18,59	N	0,38	N	0	polymorphism	1	0,01	.	.	.	.	.	.	COSM1155516	.	.	.	.	.	.	.	.
chrM	11910	11910	C	T	MI.18741	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1151	384	T	I	aCc/aTc	-2,04	0	0	benign	0,02	deleterious	0,01	neutral	2,24	neutral	-1,58	deleterious	-2,87	low_impact	1,51	neutral	0,76	neutral	0,51	deleterious	2,18	17,38	0,08	0,35	disease	0,67	disease	0,71	disease	0,53	disease	0,64	3	deleterious	0,99	deleterious	0,5	neutral	-2	neutral	0,33	medium_impact	0,87	medium_impact	-0,92	medium_impact	0,37	0,66	0,8	16,99	18,59	N	0,29	N	0,56	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11910	11910	C	A	MI.18742	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1151	384	T	N	aCc/aAc	-2,04	0	0	benign	0,26	neutral	0,06	neutral	2,28	deleterious	-3,43	neutral	-1,32	low_impact	1,25	neutral	0,71	neutral	0,53	deleterious	2,14	17,11	0,23	0,45	disease	0,89	disease	0,75	disease	0,55	disease	0,76	5	neutral	0,93	neutral	0,4	neutral	-6	neutral	0,43	medium_impact	-0,29	medium_impact	-0,47	medium_impact	0,11	0,56	0,8	16,99	18,59	N	0,32	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11910	11910	C	G	MI.18743	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1151	384	T	S	aCc/aGc	-2,04	0	0	benign	0,02	neutral	1	neutral	2,42	neutral	-0,56	neutral	1,1	neutral_impact	-1,12	neutral	0,76	neutral	0,99	neutral	-1,01	0,02	0,32	0,5	disease	0,56	neutral	0,08	neutral	0,17	neutral	0,35	3	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,14	medium_impact	0,87	high_impact	1,88	low_impact	-2,23	0,74	0,85	16,99	18,59	N	0,37	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11912	11912	A	T	MI.18744	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1153	385	T	S	Acg/Tcg	-1,12	0	0	benign	0,01	neutral	0,16	neutral	2,31	neutral	0,32	neutral	-0,01	neutral_impact	0,14	neutral	0,8	neutral	0,99	neutral	-0,45	0,29	0,42	0,55	disease	0,51	neutral	0,25	neutral	0,22	neutral	0,34	3	neutral	0,84	deleterious	0,58	neutral	-6	neutral	0,14	medium_impact	1,16	medium_impact	-0,2	medium_impact	-0,99	0,74	0,85	13,29	16,64	N	0,44	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11912	11912	A	C	MI.18745	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1153	385	T	P	Acg/Ccg	-1,12	0	0	possibly_damaging	0,55	deleterious	0	neutral	2,16	neutral	3,82	deleterious	-2,55	low_impact	1,28	neutral	0,66	neutral	0,42	deleterious	1,81	15,05	0,04	0,35	disease	0,83	disease	0,8	disease	0,65	disease	0,81	6	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,46	medium_impact	-0,8	low_impact	-1,48	medium_impact	0,14	0,41	0,8	13,29	16,64	N	0,29	N	0,57	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11912	11912	A	G	MI.18746	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1153	385	T	A	Acg/Gcg	-1,12	0	0	benign	0,08	neutral	0,18	neutral	2,49	neutral	0,29	neutral	-0,91	neutral_impact	0,24	neutral	0,72	neutral	0,96	deleterious	0,46	7,16	0,27	0,45	disease	0,63	neutral	0,33	disease	0,52	disease	0,62	2	neutral	0,8	deleterious	0,55	neutral	-6	neutral	0,15	medium_impact	0,28	medium_impact	-0,17	medium_impact	-0,89	0,28	0,8	13,29	16,64	N	0,43	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11913	11913	C	A	MI.18747	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1154	385	T	K	aCg/aAg	-2,73	0	0	benign	0,18	deleterious	0	neutral	2,18	neutral	4,23	neutral	-1,87	low_impact	1,28	neutral	0,7	neutral	0,51	deleterious	2,74	21,1	0,04	0,35	disease	0,85	disease	0,63	disease	0,63	disease	0,75	5	deleterious	1	neutral	0,41	neutral	-2	neutral	0,3	medium_impact	-0,1	low_impact	-1,48	medium_impact	0,14	0,46	0,8	13,29	16,64	N	0,31	N	0,37	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11913	11913	C	T	MI.18748	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1154	385	T	M	aCg/aTg	-2,73	0	0	benign	0,05	neutral	0,34	neutral	2,2	neutral	-1,71	neutral	-0,66	neutral_impact	-0,14	neutral	0,65	neutral	0,97	deleterious	0,63	8,34	0,13	0,4	disease	0,54	neutral	0,25	neutral	0,2	disease	0,52	0	neutral	0,63	deleterious	0,65	neutral	-6	neutral	0,14	medium_impact	0,48	medium_impact	0,04	low_impact	-1,26	0,57	0,8	13,29	16,64	N	0,48	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11915	11915	T	C	MI.18749	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1156	386	F	L	Ttc/Ctc	-2,96	0	0	probably_damaging	1	neutral	0,47	neutral	2,16	neutral	2,77	deleterious	-5,45	medium_impact	2,28	neutral	0,77	damaging	0,21	deleterious	4,14	23,8	0,21	0,45	disease	0,59	disease	0,72	neutral	0,36	disease	0,53	1	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,7	low_impact	-3,54	medium_impact	0,17	medium_impact	1,13	0,6	0,8	46,62	8,86	N	0,32	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8568	8568	C	A	MI.1875	MT-ATP8	V	ENSG00000228253	ENSP00000355265	ENST00000361851	ATP8_HUMAN	P03928	4509	YP_003024030.1	203	68	S	Y	tCc/tAc	1,75	0,01	0	probably_damaging	0,97	neutral	1	neutral	1,62	deleterious	-3,7	neutral	-0,77	low_impact	0,86	neutral	0,99	damaging	0,13	deleterious	4,37	24,1	0,55484047	0,85	NA	NA	neutral	0,09	disease	0,7	neutral	0,18	6	neutral	0,97	deleterious	0,52	neutral	-2	deleterious	0,87	low_impact	-2,19	high_impact	1,98	medium_impact	-0,36	0,61	0,85	NA	NA	N	0,35	N	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11915	11915	T	G	MI.18750	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1156	386	F	V	Ttc/Gtc	-2,96	0	0	probably_damaging	1	neutral	0,4	neutral	2,1	neutral	1,39	deleterious	-6,35	medium_impact	2,82	neutral	0,71	damaging	0,15	deleterious	4,23	23,9	0,09	0,35	disease	0,53	disease	0,74	disease	0,54	disease	0,53	1	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0,1	medium_impact	1,66	0,32	0,8	46,62	8,86	N	0,31	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11915	11915	T	A	MI.18751	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1156	386	F	I	Ttc/Atc	-2,96	0	0	probably_damaging	1	neutral	0,41	neutral	2,11	neutral	0,84	deleterious	-5,46	medium_impact	2,82	neutral	0,8	damaging	0,2	deleterious	4,52	24,3	0,19	0,45	neutral	0,5	disease	0,71	neutral	0,32	neutral	0,49	0	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	0,11	medium_impact	1,66	0,54	0,8	46,62	8,86	N	0,31	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11916	11916	T	A	MI.18752	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1157	386	F	Y	tTc/tAc	4,63	1	0	probably_damaging	1	neutral	0,22	neutral	2,04	neutral	-2,29	deleterious	-2,51	medium_impact	2,45	neutral	0,75	damaging	0,21	deleterious	4,34	24	0,21	0,45	disease	0,61	disease	0,7	neutral	0,34	disease	0,53	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	-0,11	medium_impact	1,3	0,59	0,8	46,62	8,86	P	0,56	P	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11916	11916	T	G	MI.18753	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1157	386	F	C	tTc/tGc	4,63	1	0	probably_damaging	1	neutral	0,07	neutral	1,97	neutral	1,16	deleterious	-7,29	high_impact	4,1	neutral	0,76	damaging	0,15	deleterious	4,23	23,9	0,04	0,35	disease	0,9	disease	0,87	disease	0,55	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,43	high_impact	2,93	0,15	0,8	46,62	8,86	P	0,53	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11916	11916	T	C	MI.18754	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1157	386	F	S	tTc/tCc	4,63	1	0	probably_damaging	1	neutral	0,07	neutral	2,02	neutral	-1,81	deleterious	-7,29	high_impact	4,1	neutral	0,75	damaging	0,19	deleterious	4,34	24,1	0,03	0,35	disease	0,77	disease	0,85	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,81	low_impact	-3,54	medium_impact	-0,43	high_impact	2,93	0,11	0,8	46,62	8,86	P	0,61	P	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11917	11917	C	G	MI.18755	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1158	386	F	L	ttC/ttG	5,55	1	0	probably_damaging	1	neutral	0,47	neutral	2,16	neutral	2,77	deleterious	-5,45	medium_impact	2,28	neutral	0,77	damaging	0,21	deleterious	4,44	24,2	0,21	0,45	disease	0,59	disease	0,72	neutral	0,36	disease	0,53	1	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,7	low_impact	-3,54	medium_impact	0,17	medium_impact	1,13	0,6	0,8	46,62	8,86	N	0,51	P	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11917	11917	C	A	MI.18756	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1158	386	F	L	ttC/ttA	5,55	1	0	probably_damaging	1	neutral	0,47	neutral	2,16	neutral	2,77	deleterious	-5,45	medium_impact	2,28	neutral	0,77	damaging	0,21	deleterious	4,69	24,6	0,21	0,45	disease	0,59	disease	0,72	neutral	0,36	disease	0,53	1	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,7	low_impact	-3,54	medium_impact	0,17	medium_impact	1,13	0,6	0,8	46,62	8,86	N	0,51	P	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11918	11918	T	G	MI.18757	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1159	387	S	A	Tcc/Gcc	-0,43	0,24	0	probably_damaging	0,99	neutral	0,11	neutral	2,25	neutral	-1,43	deleterious	-2,67	medium_impact	2,87	neutral	0,73	damaging	0,19	deleterious	3,63	23,2	0,31	0,45	disease	0,66	neutral	0,42	disease	0,58	disease	0,66	3	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,67	low_impact	-2,59	medium_impact	-0,31	medium_impact	1,71	0,17	0,8	43,14	8,74	N	0,35	N	0,51	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11918	11918	T	A	MI.18758	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1159	387	S	T	Tcc/Acc	-0,43	0,24	0	probably_damaging	1	neutral	0,11	neutral	2,19	neutral	0,15	neutral	-1,99	medium_impact	2,61	neutral	0,79	neutral	0,5	deleterious	3,76	23,3	0,34	0,5	disease	0,59	neutral	0,39	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,68	low_impact	-3,54	medium_impact	-0,31	medium_impact	1,46	0,36	0,8	43,14	8,74	N	0,33	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11918	11918	T	C	MI.18759	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1159	387	S	P	Tcc/Ccc	-0,43	0,24	0	probably_damaging	1	neutral	0,05	neutral	2,15	deleterious	-4,12	deleterious	-3,94	medium_impact	3,07	damaging	0,59	damaging	0,1	deleterious	4,05	23,7	0,1	0,4	disease	0,88	disease	0,87	disease	0,72	disease	0,81	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,84	low_impact	-3,54	medium_impact	-0,52	medium_impact	1,91	0,15	0,8	43,14	8,74	N	0,31	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5904	5904	A	T	MI.1876	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1	1	M	L	Atg/Ttg	-1,96	0	0	possibly_damaging	0,7	neutral	0,06	neutral	3,13	neutral	1,41	neutral	-0,1	NA	NA	neutral	0,62	damaging	0,12	deleterious	1,94	15,84	0,4	0,55	neutral	0,24	neutral	0,13	neutral	0,22	neutral	0,15	7	neutral	0,95	neutral	0,18	neutral	-1	deleterious	0,49	NA	NA	NA	NA	NA	NA	0,57	0,9	3,12	6,73	N	0,48	N	0,6	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11919	11919	C	A	MI.18760	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1160	387	S	Y	tCc/tAc	2,56	0,72	0	probably_damaging	1	neutral	0,06	neutral	2,13	deleterious	-3,37	deleterious	-4,55	medium_impact	2,61	neutral	0,74	damaging	0,14	deleterious	4,19	23,8	0,13	0,4	disease	0,67	disease	0,73	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,46	0,2	0,8	43,14	8,74	N	0,35	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11919	11919	C	T	MI.18761	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1160	387	S	F	tCc/tTc	2,56	0,72	0	probably_damaging	1	neutral	0,14	neutral	2,12	neutral	-2,9	deleterious	-4,84	medium_impact	3,42	neutral	0,65	damaging	0,1	deleterious	4,42	24,2	0,15	0,45	disease	0,56	disease	0,78	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	-0,24	high_impact	2,26	0,05	0,8	43,14	8,74	N	0,4	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	C11919T	Thyroid Cancer Cell Line	+	-	Reported	1
chrM	11919	11919	C	G	MI.18762	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1160	387	S	C	tCc/tGc	2,56	0,72	0	probably_damaging	1	deleterious	0,01	neutral	2,11	deleterious	-4,12	deleterious	-4,22	medium_impact	3,42	neutral	0,64	damaging	0,09	deleterious	3,73	23,3	0,12	0,4	disease	0,87	disease	0,74	neutral	0,48	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,77	low_impact	-3,54	medium_impact	-0,92	high_impact	2,26	0,24	0,8	43,14	8,74	N	0,37	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11921	11921	T	G	MI.18763	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1162	388	W	G	Tga/Gga	-2,5	0	0	probably_damaging	1	deleterious	0,01	neutral	2,26	neutral	0,07	deleterious	-12,1	high_impact	4,21	damaging	0,54	damaging	0,08	deleterious	3,99	23,6	0,07	0,35	disease	0,9	disease	0,83	disease	0,82	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-3,54	medium_impact	-0,92	high_impact	3,04	0,17	0,8	46,84	9,32	N	0,45	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11921	11921	T	C	MI.18764	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1162	388	W	R	Tga/Cga	-2,5	0	0	probably_damaging	1	deleterious	0,01	neutral	2,26	neutral	-2,58	deleterious	-13,03	high_impact	4,21	damaging	0,55	damaging	0,07	deleterious	3,65	23,2	0,08	0,35	disease	0,88	disease	0,89	disease	0,86	disease	0,85	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,54	medium_impact	-0,92	high_impact	3,04	0,11	0,8	46,84	9,32	N	0,48	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11922	11922	G	T	MI.18765	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1163	388	W	L	tGa/tTa	7,4	1	0	probably_damaging	1	neutral	0,09	neutral	2,28	neutral	0,39	deleterious	-12,1	high_impact	3,66	damaging	0,54	damaging	0,05	deleterious	4,4	24,1	0,11	0,4	neutral	0,31	disease	0,83	disease	0,8	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,72	low_impact	-3,54	medium_impact	-0,36	high_impact	2,5	0,2	0,8	46,84	9,32	P	0,6	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11922	11922	G	C	MI.18766	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1163	388	W	S	tGa/tCa	7,4	1	0	probably_damaging	1	neutral	0,07	neutral	2,31	neutral	-0,14	deleterious	-13,03	high_impact	3,66	damaging	0,53	damaging	0,08	deleterious	4,2	23,9	0,11	0,4	disease	0,83	disease	0,89	disease	0,81	disease	0,77	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,43	high_impact	2,5	0,19	0,8	46,84	9,32	P	0,61	P	0,94	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11923	11923	A	T	MI.18767	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1164	388	W	C	tgA/tgT	6,01	1	0	probably_damaging	1	deleterious	0	neutral	2,2	deleterious	-5,12	deleterious	-12,1	high_impact	4,21	damaging	0,52	damaging	0,05	deleterious	4,24	23,9	0,08	0,35	disease	0,92	disease	0,89	disease	0,83	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,04	0,11	0,8	46,84	9,32	P	0,61	P	0,98	polymorphism	1	0,1	rs386829142	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11923	11923	A	C	MI.18768	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1164	388	W	C	tgA/tgC	6,01	1	0	probably_damaging	1	deleterious	0	neutral	2,2	deleterious	-5,12	deleterious	-12,1	high_impact	4,21	damaging	0,52	damaging	0,05	deleterious	4,16	23,8	0,08	0,35	disease	0,92	disease	0,89	disease	0,83	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,04	0,11	0,8	46,84	9,32	P	0,6	P	0,98	polymorphism	1	0,1	rs386829142	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11924	11924	T	A	MI.18769	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1165	389	S	T	Tca/Aca	2,1	1	0	benign	0,31	deleterious	0,03	neutral	2,14	neutral	-0,46	deleterious	-2,7	medium_impact	2,53	neutral	0,74	neutral	0,58	deleterious	2,01	16,24	0,3	0,45	disease	0,85	disease	0,58	neutral	0,47	disease	0,56	1	neutral	0,97	neutral	0,36	deleterious	1	neutral	0,35	medium_impact	-0,39	medium_impact	-0,64	medium_impact	1,38	0,55	0,8	37,04	8,06	P	0,52	P	0,72	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5904	5904	A	C	MI.1877	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1	1	M	L	Atg/Ctg	-1,96	0	0	possibly_damaging	0,7	neutral	0,06	neutral	3,13	neutral	1,41	neutral	-0,1	NA	NA	neutral	0,62	damaging	0,12	deleterious	1,93	15,75	0,4	0,55	neutral	0,24	neutral	0,13	neutral	0,22	neutral	0,15	7	neutral	0,95	neutral	0,18	neutral	-1	deleterious	0,49	NA	NA	NA	NA	NA	NA	0,57	0,9	3,12	6,73	N	0,48	N	0,6	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11924	11924	T	C	MI.18770	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1165	389	S	P	Tca/Cca	2,1	1	0	possibly_damaging	0,77	deleterious	0,01	neutral	2,07	deleterious	-4,11	deleterious	-4,53	high_impact	3,98	neutral	0,68	neutral	0,53	deleterious	2,21	17,54	0,06	0,35	disease	0,97	disease	0,83	disease	0,76	disease	0,85	7	deleterious	0,99	neutral	0,12	deleterious	5	deleterious	0,54	low_impact	-1,21	medium_impact	-0,92	high_impact	2,81	0,17	0,8	37,04	8,06	P	0,58	P	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11924	11924	T	G	MI.18771	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1165	389	S	A	Tca/Gca	2,1	1	0	benign	0,01	neutral	0,05	neutral	2,17	neutral	-1,42	deleterious	-2,59	low_impact	1,7	neutral	0,73	neutral	0,67	deleterious	1,86	15,36	0,3	0,45	neutral	0,44	disease	0,53	neutral	0,48	neutral	0,44	1	neutral	0,95	deleterious	0,52	neutral	-6	neutral	0,2	medium_impact	1,16	medium_impact	-0,52	medium_impact	0,56	0,31	0,8	37,04	8,06	P	0,55	P	0,51	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11925	11925	C	G	MI.18772	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1166	389	S	W	tCa/tGa	7,4	1	0	probably_damaging	0,91	deleterious	0,01	neutral	2,05	deleterious	-5,54	deleterious	-6,31	high_impact	3,63	neutral	0,7	neutral	0,49	deleterious	2,81	21,4	0,07	0,35	disease	1	disease	0,88	disease	0,73	disease	0,86	7	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,73	low_impact	-1,66	medium_impact	-0,92	high_impact	2,47	0,11	0,8	37,04	8,06	P	0,55	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11925	11925	C	T	MI.18773	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1166	389	S	L	tCa/tTa	7,4	1	0	possibly_damaging	0,44	deleterious	0,04	neutral	2,12	neutral	0,79	deleterious	-5,39	high_impact	3,63	neutral	0,71	neutral	0,5	deleterious	2,78	21,2	0,09	0,4	disease	0,94	disease	0,85	disease	0,65	disease	0,82	6	neutral	0,95	neutral	0,3	deleterious	5	neutral	0,35	medium_impact	-0,62	medium_impact	-0,57	high_impact	2,47	0,35	0,8	37,04	8,06	P	0,64	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11927	11927	A	T	MI.18774	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1168	390	N	Y	Aat/Tat	-11,71	0	0	benign	0	neutral	1	neutral	2,17	neutral	-0,54	deleterious	-5,27	low_impact	1,84	neutral	0,75	neutral	0,63	deleterious	1,97	16	0,15	0,45	disease	0,8	disease	0,54	neutral	0,15	disease	0,58	1	neutral	0	deleterious	1	neutral	-6	deleterious	0,74	high_impact	2,1	high_impact	1,88	medium_impact	0,69	0,24	0,8	21,13	24,27	N	0,3	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11927	11927	A	C	MI.18775	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1168	390	N	H	Aat/Cat	-11,71	0	0	benign	0	neutral	0,54	neutral	2,2	neutral	3	deleterious	-3,12	low_impact	1,04	neutral	0,75	neutral	0,76	neutral	1,67	14,26	0,38	0,5	disease	0,52	disease	0,51	neutral	0,23	neutral	0,45	1	neutral	0,46	deleterious	0,77	neutral	-6	deleterious	0,69	high_impact	2,1	medium_impact	0,24	medium_impact	-0,1	0,26	0,8	21,13	24,27	N	0,35	N	0,37	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11927	11927	A	G	MI.18776	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1168	390	N	D	Aat/Gat	-11,71	0	0	benign	0,12	neutral	0,21	neutral	2,2	neutral	3,67	deleterious	-3,38	medium_impact	2,19	neutral	0,78	neutral	0,5	deleterious	2,67	20,6	0,54	0,6	disease	0,62	neutral	0,48	neutral	0,39	disease	0,59	2	neutral	0,76	deleterious	0,55	neutral	-3	deleterious	0,7	medium_impact	0,1	medium_impact	-0,12	medium_impact	1,04	0,32	0,8	21,13	24,27	N	0,38	N	0,9	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11928	11928	A	T	MI.18777	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1169	390	N	I	aAt/aTt	-0,66	0	0	benign	0,27	neutral	0,39	neutral	2,16	neutral	2,32	deleterious	-6,42	medium_impact	2,4	neutral	0,78	neutral	0,5	deleterious	2,57	19,9	0,17	0,45	neutral	0,45	disease	0,63	neutral	0,29	disease	0,5	0	neutral	0,53	deleterious	0,56	neutral	-3	deleterious	0,69	medium_impact	-0,31	medium_impact	0,09	medium_impact	1,25	0,18	0,8	21,13	24,27	N	0,36	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11928	11928	A	G	MI.18778	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1169	390	N	S	aAt/aGt	-0,66	0	0	benign	0,08	neutral	0,4	neutral	2,26	neutral	0,72	deleterious	-3,16	low_impact	1,5	neutral	0,69	neutral	0,89	neutral	1,61	13,93	0,43	0,55	disease	0,56	neutral	0,34	neutral	0,31	disease	0,6	2	neutral	0,55	deleterious	0,66	neutral	-6	deleterious	0,66	medium_impact	0,28	medium_impact	0,1	medium_impact	0,36	0,21	0,8	21,13	24,27	N	0,38	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	COSM1138240	.	.	.	.	.	.	.	.
chrM	11928	11928	A	C	MI.18779	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1169	390	N	T	aAt/aCt	-0,66	0	0	benign	0,15	neutral	0,39	neutral	2,22	neutral	1,48	deleterious	-3,99	low_impact	1,17	neutral	0,76	neutral	0,69	deleterious	2,03	16,41	0,35	0,5	neutral	0,42	neutral	0,33	neutral	0,15	neutral	0,47	1	neutral	0,54	deleterious	0,62	neutral	-6	deleterious	0,65	medium_impact	-0,01	medium_impact	0,09	medium_impact	0,03	0,26	0,8	21,13	24,27	N	0,46	N	0,75	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5904	5904	A	G	MI.1878	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1	1	M	V	Atg/Gtg	-1,96	0	0	possibly_damaging	0,79	deleterious	0	neutral	3,07	neutral	1,02	neutral	-0,13	NA	NA	damaging	0,59	damaging	0,13	deleterious	2,43	19	0,62	0,65	neutral	0,25	neutral	0,18	neutral	0,2	neutral	0,23	5	deleterious	1	neutral	0,11	deleterious	3	deleterious	0,54	NA	NA	NA	NA	NA	NA	0,37	0,9	3,12	6,73	N	0,46	N	0,87	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11929	11929	T	A	MI.18780	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1170	390	N	K	aaT/aaA	0,49	0	0,01	benign	0	neutral	0,3	neutral	2,23	neutral	1,76	deleterious	-3,66	low_impact	1,36	neutral	0,8	neutral	0,57	deleterious	3,17	22,6	0,37	0,5	neutral	0,5	disease	0,52	neutral	0,42	neutral	0,47	1	neutral	0,7	deleterious	0,65	neutral	-6	deleterious	0,72	high_impact	2,1	medium_impact	0	medium_impact	0,22	0,29	0,8	21,13	24,27	N	0,35	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11929	11929	T	G	MI.18781	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1170	390	N	K	aaT/aaG	0,49	0	0,01	benign	0	neutral	0,3	neutral	2,23	neutral	1,76	deleterious	-3,66	low_impact	1,36	neutral	0,8	neutral	0,57	deleterious	2,84	21,6	0,37	0,5	neutral	0,5	disease	0,52	neutral	0,42	neutral	0,47	1	neutral	0,7	deleterious	0,65	neutral	-6	deleterious	0,72	high_impact	2,1	medium_impact	0	medium_impact	0,22	0,29	0,8	21,13	24,27	N	0,33	N	0,94	polymorphism	1	0,06	rs28722520	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11930	11930	A	C	MI.18782	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1171	391	I	L	Atc/Ctc	-5,04	0	0	benign	0	neutral	0,99	neutral	2,32	neutral	3,78	neutral	0,26	low_impact	0,86	neutral	0,71	neutral	0,94	deleterious	0,3	5,73	0,25	0,45	neutral	0,46	neutral	0,24	neutral	0,19	neutral	0,45	1	neutral	0	deleterious	1	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	1,32	medium_impact	-0,28	0,49	0,8	24,4	18,82	N	0,42	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11930	11930	A	G	MI.18783	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1171	391	I	V	Atc/Gtc	-5,04	0	0	benign	0	neutral	0,61	neutral	2,27	neutral	1,42	neutral	-0,44	low_impact	1,26	neutral	0,78	neutral	0,77	deleterious	0,01	2,65	0,35	0,5	neutral	0,41	neutral	0,16	neutral	0,42	neutral	0,31	4	neutral	0,39	deleterious	0,81	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,31	medium_impact	0,12	0,36	0,8	24,4	18,82	N	0,33	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11930	11930	A	T	MI.18784	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1171	391	I	F	Atc/Ttc	-5,04	0	0	benign	0	neutral	1	neutral	2,16	neutral	-0,28	neutral	1,28	neutral_impact	0,63	neutral	0,71	neutral	0,96	deleterious	0,13	3,93	0,18	0,45	disease	0,66	neutral	0,39	neutral	0,24	disease	0,62	2	neutral	0	deleterious	1	neutral	-6	neutral	0,21	high_impact	2,1	high_impact	1,88	medium_impact	-0,5	0,54	0,8	24,4	18,82	N	0,29	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11931	11931	T	C	MI.18785	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1172	391	I	T	aTc/aCc	-1,12	0	0	benign	0	neutral	0,49	neutral	2,15	neutral	1,75	neutral	-1,3	neutral_impact	0,25	neutral	0,76	neutral	0,98	deleterious	0,36	6,21	0,11	0,4	disease	0,55	neutral	0,26	neutral	0,29	disease	0,52	0	neutral	0,51	deleterious	0,75	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,19	medium_impact	-0,88	0,23	0,8	24,4	18,82	N	0,41	N	0,02	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11931	11931	T	G	MI.18786	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1172	391	I	S	aTc/aGc	-1,12	0	0	benign	0,02	neutral	0,34	neutral	2,12	neutral	1,42	neutral	-1,93	low_impact	1,57	neutral	0,79	neutral	0,69	deleterious	2,36	18,58	0,04	0,35	disease	0,62	disease	0,58	neutral	0,45	neutral	0,5	0	neutral	0,65	deleterious	0,66	neutral	-6	neutral	0,2	medium_impact	0,87	medium_impact	0,04	medium_impact	0,43	0,2	0,8	24,4	18,82	N	0,3	N	0,21	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11931	11931	T	A	MI.18787	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1172	391	I	N	aTc/aAc	-1,12	0	0	benign	0,07	neutral	0,23	neutral	2,08	neutral	-2,16	deleterious	-2,87	medium_impact	2,54	neutral	0,7	neutral	0,5	deleterious	2,48	19,36	0,09	0,35	disease	0,89	disease	0,65	neutral	0,45	disease	0,64	3	neutral	0,75	deleterious	0,58	neutral	-3	neutral	0,27	medium_impact	0,34	medium_impact	-0,09	medium_impact	1,39	0,2	0,8	24,4	18,82	N	0,35	N	0,41	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11932	11932	C	G	MI.18788	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1173	391	I	M	atC/atG	0,49	0	0	benign	0,01	neutral	0,36	neutral	2,12	neutral	2,55	neutral	0,24	low_impact	1,14	neutral	0,77	neutral	0,93	deleterious	0,3	5,68	0,25	0,45	disease	0,77	neutral	0,27	neutral	0,27	disease	0,59	2	neutral	0,63	deleterious	0,68	neutral	-6	neutral	0,25	medium_impact	1,16	medium_impact	0,06	medium_impact	0	0,49	0,8	24,4	18,82	N	0,44	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11932	11932	C	A	MI.18789	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1173	391	I	M	atC/atA	0,49	0	0	benign	0,01	neutral	0,36	neutral	2,12	neutral	2,55	neutral	0,24	low_impact	1,14	neutral	0,77	neutral	0,93	deleterious	0,75	9,12	0,25	0,45	disease	0,77	neutral	0,27	neutral	0,27	disease	0,59	2	neutral	0,63	deleterious	0,68	neutral	-6	neutral	0,25	medium_impact	1,16	medium_impact	0,06	medium_impact	0	0,49	0,8	24,4	18,82	N	0,44	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5905	5905	T	A	MI.1879	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	2	1	M	K	aTg/aAg	3,83	1	0	possibly_damaging	0,9	deleterious	0	neutral	2,99	neutral	0,1	neutral	-0,2	NA	NA	neutral	0,62	damaging	0,11	deleterious	3,76	23,3	0,21	0,55	neutral	0,14	neutral	0,39	disease	0,55	neutral	0,37	3	deleterious	1	neutral	0,05	deleterious	3	deleterious	0,68	NA	NA	NA	NA	NA	NA	0,49	0,9	3,12	6,73	P	0,55	P	0,93	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11933	11933	A	T	MI.18790	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1174	392	T	S	Act/Tct	-8,03	0	0	benign	0,16	neutral	0,62	neutral	2,25	neutral	-0,13	deleterious	-2,5	medium_impact	2,27	neutral	0,75	neutral	0,89	deleterious	2,04	16,48	0,41	0,5	neutral	0,44	neutral	0,41	neutral	0,36	neutral	0,41	2	neutral	0,27	deleterious	0,73	neutral	-3	deleterious	0,69	medium_impact	-0,04	medium_impact	0,32	medium_impact	1,12	0,72	0,85	20,04	18,33	N	0,36	N	0,25	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11933	11933	A	G	MI.18791	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1174	392	T	A	Act/Gct	-8,03	0	0	possibly_damaging	0,58	neutral	0,2	neutral	2,38	neutral	2,03	deleterious	-3,77	medium_impact	3,04	neutral	0,68	damaging	0,28	deleterious	3,52	23,1	0,26	0,45	disease	0,51	disease	0,63	neutral	0,42	neutral	0,46	1	neutral	0,8	neutral	0,31	NA	0	deleterious	0,71	medium_impact	-0,85	medium_impact	-0,14	medium_impact	1,88	0,43	0,8	20,04	18,33	N	0,39	N	0,74	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11933	11933	A	C	MI.18792	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1174	392	T	P	Act/Cct	-8,03	0	0	probably_damaging	0,96	neutral	0,07	neutral	2,23	deleterious	-3,35	deleterious	-4,88	high_impact	4,14	neutral	0,66	damaging	0,14	deleterious	3,56	23,1	0,07	0,35	disease	0,7	disease	0,86	disease	0,75	disease	0,79	6	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,81	low_impact	-2,01	medium_impact	-0,43	high_impact	2,97	0,35	0,8	20,04	18,33	N	0,4	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11934	11934	C	T	MI.18793	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1175	392	T	I	aCt/aTt	1,87	0,83	0	probably_damaging	0,96	neutral	0,26	neutral	2,29	neutral	1,82	deleterious	-5,05	high_impact	3,6	neutral	0,76	damaging	0,17	deleterious	3,99	23,6	0,15	0,45	disease	0,55	disease	0,85	disease	0,61	disease	0,69	4	neutral	0,97	neutral	0,15	deleterious	2	deleterious	0,76	low_impact	-2,01	medium_impact	-0,05	high_impact	2,44	0,77	0,85	20,04	18,33	N	0,37	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11934	11934	C	A	MI.18794	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1175	392	T	N	aCt/aAt	1,87	0,83	0	possibly_damaging	0,79	neutral	0,12	neutral	2,23	neutral	0,66	deleterious	-3,78	high_impact	3,6	neutral	0,73	damaging	0,16	deleterious	3,66	23,2	0,26	0,45	disease	0,84	disease	0,8	disease	0,64	disease	0,71	4	neutral	0,92	neutral	0,17	deleterious	1	deleterious	0,78	low_impact	-1,26	medium_impact	-0,28	high_impact	2,44	0,56	0,8	20,04	18,33	N	0,39	N	0,72	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11934	11934	C	G	MI.18795	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1175	392	T	S	aCt/aGt	1,87	0,83	0	benign	0,16	neutral	0,62	neutral	2,25	neutral	-0,13	deleterious	-2,5	medium_impact	2,27	neutral	0,75	neutral	0,89	deleterious	2,24	17,8	0,41	0,5	neutral	0,44	neutral	0,41	neutral	0,36	neutral	0,41	2	neutral	0,27	deleterious	0,73	neutral	-3	deleterious	0,69	medium_impact	-0,04	medium_impact	0,32	medium_impact	1,12	0,72	0,85	20,04	18,33	N	0,34	N	0,25	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11936	11936	C	T	MI.18796	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1177	393	L	F	Ctc/Ttc	-7,8	0	0	benign	0	neutral	0,47	neutral	2,04	neutral	-0,6	neutral	-2,23	neutral_impact	0,6	neutral	0,77	neutral	0,82	deleterious	2,14	17,14	0,25	0,45	disease	0,8	disease	0,57	neutral	0,29	disease	0,6	2	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,32	high_impact	2,1	medium_impact	0,17	medium_impact	-0,53	0,63	0,8	14,81	10,65	N	0,27	N	0,16	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11936	11936	C	G	MI.18797	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1177	393	L	V	Ctc/Gtc	-7,8	0	0	benign	0,01	neutral	0,2	neutral	2,07	neutral	0,04	neutral	-0,04	low_impact	0,82	neutral	0,82	neutral	0,88	neutral	1,5	13,29	0,27	0,45	disease	0,54	neutral	0,42	neutral	0,25	disease	0,57	1	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,15	medium_impact	1,16	medium_impact	-0,14	medium_impact	-0,32	0,63	0,8	14,81	10,65	N	0,43	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11936	11936	C	A	MI.18798	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1177	393	L	I	Ctc/Atc	-7,8	0	0	benign	0	neutral	1	neutral	2,1	neutral	-0,3	neutral	0,76	neutral_impact	-2,04	neutral	0,72	neutral	0,95	neutral	-0,51	0,21	0,3	0,45	neutral	0,49	neutral	0,05	neutral	0,15	neutral	0,22	6	neutral	0	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,1	high_impact	1,88	low_impact	-3,14	0,54	0,8	14,81	10,65	N	0,37	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11937	11937	T	G	MI.18799	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1178	393	L	R	cTc/cGc	0,26	0,02	0	benign	0,33	deleterious	0,03	neutral	1,96	deleterious	-5,09	deleterious	-4,6	medium_impact	2,02	neutral	0,65	neutral	0,48	deleterious	2,58	19,99	0,02	0,35	disease	0,84	disease	0,89	disease	0,69	disease	0,79	6	neutral	0,97	neutral	0,35	deleterious	1	deleterious	0,62	medium_impact	-0,43	medium_impact	-0,64	medium_impact	0,87	0,26	0,8	14,81	10,65	N	0,28	N	0,6	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8615	8615	T	G	MI.188	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	89	30	L	W	tTg/tGg	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	4,22	neutral	-2,44	deleterious	-4,67	medium_impact	3,42	neutral	0,79	neutral	0,42	deleterious	3,58	23,2	0,16	0,65	disease	0,92	disease	0,67	neutral	0,28	disease	0,69	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,82	low_impact	-3,6	low_impact	-1,4	medium_impact	1,83	0,52	0,9	17,7	14,1	N	0,36	N	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5905	5905	T	C	MI.1880	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	2	1	M	T	aTg/aCg	3,83	1	0	possibly_damaging	0,9	deleterious	0	neutral	2,98	neutral	0	neutral	-0,15	NA	NA	neutral	0,62	damaging	0,09	deleterious	2,71	20,9	0,47	0,55	neutral	0,16	neutral	0,29	disease	0,52	neutral	0,35	3	deleterious	1	neutral	0,05	deleterious	3	deleterious	0,68	NA	NA	NA	NA	NA	NA	0,25	0,9	3,12	6,73	P	0,49	N	0,8	NA	NA	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11937	11937	T	C	MI.18800	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1178	393	L	P	cTc/cCc	0,26	0,02	0	possibly_damaging	0,5	deleterious	0,02	neutral	1,98	deleterious	-5,66	deleterious	-4,89	medium_impact	2,02	damaging	0,6	neutral	0,42	deleterious	3,52	23,1	0,02	0,35	disease	0,7	disease	0,88	disease	0,69	disease	0,79	6	neutral	0,98	neutral	0,26	deleterious	4	deleterious	0,69	medium_impact	-0,72	medium_impact	-0,75	medium_impact	0,87	0,35	0,8	14,81	10,65	N	0,28	N	0,69	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11937	11937	T	A	MI.18801	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1178	393	L	H	cTc/cAc	0,26	0,02	0	possibly_damaging	0,67	neutral	0,05	neutral	1,96	deleterious	-5,62	deleterious	-4,9	medium_impact	2,02	neutral	0,73	neutral	0,56	deleterious	3,81	23,4	0,04	0,35	disease	0,89	disease	0,74	disease	0,64	disease	0,77	5	neutral	0,95	neutral	0,19	NA	0	deleterious	0,68	low_impact	-1,01	medium_impact	-0,52	medium_impact	0,87	0,26	0,8	14,81	10,65	N	0,34	N	0,57	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11939	11939	C	G	MI.18802	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1180	394	L	V	Cta/Gta	-9,41	0	0	benign	0	neutral	0,43	neutral	2,23	neutral	0,94	neutral	-0,22	low_impact	1,05	neutral	0,77	neutral	0,97	deleterious	0,19	4,62	0,25	0,45	disease	0,57	neutral	0,31	neutral	0,24	disease	0,6	2	neutral	0,57	deleterious	0,72	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,13	medium_impact	-0,09	0,57	0,8	23,53	23,06	N	0,42	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11939	11939	C	A	MI.18803	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1180	394	L	M	Cta/Ata	-9,41	0	0	benign	0,01	neutral	0,15	neutral	2,08	neutral	-0,09	neutral	-0,65	neutral_impact	-0,1	neutral	0,77	neutral	0,84	deleterious	0,61	8,25	0,24	0,45	disease	0,63	neutral	0,32	neutral	0,25	disease	0,6	2	neutral	0,85	deleterious	0,57	neutral	-6	neutral	0,15	medium_impact	1,16	medium_impact	-0,22	low_impact	-1,23	0,35	0,8	23,53	23,06	N	0,4	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11940	11940	T	A	MI.18804	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1181	394	L	Q	cTa/cAa	-1,81	0	0	benign	0,23	deleterious	0,02	neutral	2,03	deleterious	-3,61	deleterious	-4,07	medium_impact	2,62	neutral	0,73	neutral	0,55	deleterious	2,28	18,02	0,04	0,35	disease	0,7	disease	0,71	disease	0,52	disease	0,6	2	neutral	0,98	neutral	0,4	deleterious	1	neutral	0,37	medium_impact	-0,23	medium_impact	-0,75	medium_impact	1,47	0,29	0,8	23,53	23,06	N	0,34	N	0,86	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11940	11940	T	C	MI.18805	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1181	394	L	P	cTa/cCa	-1,81	0	0	benign	0,23	neutral	0,17	neutral	2,03	neutral	-0,42	deleterious	-4,42	low_impact	1,52	neutral	0,72	neutral	0,47	deleterious	2,11	16,94	0,03	0,35	disease	0,81	disease	0,84	neutral	0,49	disease	0,67	3	neutral	0,8	deleterious	0,47	neutral	-6	deleterious	0,46	medium_impact	-0,23	medium_impact	-0,18	medium_impact	0,38	0,37	0,8	23,53	23,06	N	0,31	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11940	11940	T	G	MI.18806	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1181	394	L	R	cTa/cGa	-1,81	0	0	benign	0,23	deleterious	0,03	neutral	2,04	deleterious	-3,43	deleterious	-4,2	medium_impact	2,62	neutral	0,7	neutral	0,48	deleterious	2,41	18,86	0,02	0,35	disease	0,7	disease	0,85	disease	0,65	disease	0,77	5	neutral	0,97	neutral	0,4	deleterious	1	neutral	0,39	medium_impact	-0,23	medium_impact	-0,64	medium_impact	1,47	0,29	0,8	23,53	23,06	N	0,31	N	0,89	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11942	11942	C	G	MI.18807	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1183	395	L	V	Ctt/Gtt	-8,49	0	0	benign	0,42	neutral	0,15	neutral	2,1	neutral	0,37	neutral	-2,17	medium_impact	2,58	neutral	0,78	neutral	0,62	deleterious	3,47	23	0,21	0,45	disease	0,54	neutral	0,49	neutral	0,39	neutral	0,49	0	neutral	0,83	neutral	0,37	neutral	-3	deleterious	0,67	medium_impact	-0,59	medium_impact	-0,22	medium_impact	1,43	0,48	0,8	18,95	15,46	N	0,35	N	0,86	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11942	11942	C	T	MI.18808	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1183	395	L	F	Ctt/Ttt	-8,49	0	0	benign	0,03	neutral	0,33	neutral	1,99	neutral	1,06	neutral	-2,39	low_impact	1,16	neutral	0,8	neutral	0,7	deleterious	2,91	21,9	0,18	0,45	disease	0,8	disease	0,53	neutral	0,26	disease	0,58	2	neutral	0,65	deleterious	0,65	neutral	-6	deleterious	0,74	medium_impact	0,7	medium_impact	0,03	medium_impact	0,02	0,38	0,8	18,95	15,46	N	0,29	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11942	11942	C	A	MI.18809	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1183	395	L	I	Ctt/Att	-8,49	0	0	benign	0,42	neutral	0,29	neutral	2,17	neutral	2,21	neutral	-1,35	low_impact	1,54	neutral	0,73	neutral	0,7	deleterious	3,03	22,3	0,24	0,45	disease	0,6	neutral	0,34	neutral	0,18	disease	0,6	2	neutral	0,67	neutral	0,44	neutral	-6	deleterious	0,67	medium_impact	-0,59	medium_impact	-0,02	medium_impact	0,4	0,41	0,8	18,95	15,46	N	0,47	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5906	5906	G	T	MI.1881	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	3	1	M	I	atG/atT	5,68	1	0	possibly_damaging	0,84	deleterious	0	neutral	3,06	neutral	0,85	neutral	-0,14	NA	NA	damaging	0,55	damaging	0,13	deleterious	3,36	22,9	0,48	0,55	neutral	0,27	neutral	0,24	neutral	0,35	neutral	0,31	4	deleterious	1	neutral	0,08	deleterious	3	deleterious	0,63	NA	NA	NA	NA	NA	NA	0,51	0,9	3,12	6,73	P	0,65	P	0,85	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11943	11943	T	C	MI.18810	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1184	395	L	P	cTt/cCt	-1,81	0	0	possibly_damaging	0,84	neutral	0,18	neutral	1,92	deleterious	-3,9	deleterious	-5,65	medium_impact	2,29	neutral	0,76	neutral	0,61	deleterious	4	23,6	0,02	0,35	disease	0,93	disease	0,85	disease	0,52	disease	0,75	5	neutral	0,91	neutral	0,17	NA	0	deleterious	0,87	low_impact	-1,39	medium_impact	-0,17	medium_impact	1,14	0,26	0,8	18,95	15,46	N	0,32	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11943	11943	T	A	MI.18811	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1184	395	L	H	cTt/cAt	-1,81	0	0	probably_damaging	0,94	deleterious	0,04	neutral	1,91	deleterious	-3,86	deleterious	-5,44	high_impact	3,67	neutral	0,7	neutral	0,41	deleterious	4,28	24	0,05	0,35	disease	0,93	disease	0,81	disease	0,53	disease	0,78	6	deleterious	0,99	neutral	0,05	deleterious	6	deleterious	0,81	low_impact	-1,84	medium_impact	-0,57	high_impact	2,51	0,27	0,8	18,95	15,46	N	0,38	N	0,96	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11943	11943	T	G	MI.18812	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1184	395	L	R	cTt/cGt	-1,81	0	0	possibly_damaging	0,84	deleterious	0,03	neutral	1,91	deleterious	-3,33	deleterious	-4,88	high_impact	3,67	neutral	0,63	neutral	0,35	deleterious	4,26	23,9	0,02	0,35	disease	0,9	disease	0,88	disease	0,67	disease	0,8	6	deleterious	0,98	neutral	0,1	deleterious	5	deleterious	0,87	low_impact	-1,39	medium_impact	-0,64	high_impact	2,51	0,18	0,8	18,95	15,46	N	0,36	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11945	11945	A	T	MI.18813	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1186	396	T	S	Aca/Tca	-20	0	0	possibly_damaging	0,47	neutral	0,13	neutral	2,21	neutral	0,85	neutral	-2,28	medium_impact	3,29	neutral	0,77	neutral	0,62	neutral	1,57	13,68	0,42	0,55	disease	0,63	disease	0,65	neutral	0,45	neutral	0,47	1	neutral	0,85	neutral	0,33	NA	0	neutral	0,39	medium_impact	-0,67	medium_impact	-0,26	high_impact	2,13	0,45	0,8	33,33	24,26	N	0,4	N	0,27	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11945	11945	A	G	MI.18814	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1186	396	T	A	Aca/Gca	-20	0	0	benign	0,22	neutral	0,18	neutral	2,47	neutral	0,31	deleterious	-2,61	medium_impact	2,56	neutral	0,8	neutral	0,82	neutral	1,65	14,14	0,25	0,45	neutral	0,4	disease	0,59	neutral	0,47	neutral	0,46	1	neutral	0,79	deleterious	0,48	neutral	-3	neutral	0,28	medium_impact	-0,2	medium_impact	-0,17	medium_impact	1,41	0,28	0,8	33,33	24,26	N	0,39	N	0,33	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11945	11945	A	C	MI.18815	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1186	396	T	P	Aca/Cca	-20	0	0	possibly_damaging	0,87	deleterious	0,04	neutral	2,15	neutral	0,86	deleterious	-3,73	medium_impact	3,5	neutral	0,67	neutral	0,58	deleterious	3,24	22,8	0,05	0,35	neutral	0,45	disease	0,88	disease	0,69	disease	0,74	5	deleterious	0,98	neutral	0,09	deleterious	4	deleterious	0,64	low_impact	-1,49	medium_impact	-0,57	high_impact	2,34	0,31	0,8	33,33	24,26	N	0,44	N	0,85	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11946	11946	C	T	MI.18816	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1187	396	T	M	aCa/aTa	1,87	0	0	benign	0,07	neutral	0,42	neutral	2,19	neutral	-0,94	neutral	-1,3	low_impact	1,53	neutral	0,82	neutral	0,93	neutral	1,04	10,89	0,13	0,4	disease	0,58	disease	0,59	neutral	0,3	neutral	0,49	0	neutral	0,53	deleterious	0,68	neutral	-6	deleterious	0,49	medium_impact	0,34	medium_impact	0,12	medium_impact	0,39	0,4	0,8	33,33	24,26	N	0,33	N	0,14	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11946	11946	C	A	MI.18817	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1187	396	T	K	aCa/aAa	1,87	0	0	possibly_damaging	0,6	deleterious	0,02	neutral	2,15	neutral	-0,36	deleterious	-3,33	high_impact	3,84	neutral	0,78	neutral	0,51	deleterious	2,79	21,3	0,1	0,4	disease	0,79	disease	0,86	disease	0,68	disease	0,75	5	deleterious	0,98	neutral	0,21	deleterious	5	deleterious	0,56	medium_impact	-0,88	medium_impact	-0,75	high_impact	2,67	0,4	0,8	33,33	24,26	N	0,42	N	0,7	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11948	11948	G	C	MI.18818	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1189	397	G	R	Gga/Cga	-3,42	0	0	probably_damaging	1	neutral	0,34	neutral	2,08	deleterious	-4,52	deleterious	-7,12	high_impact	4,11	neutral	0,72	damaging	0,1	deleterious	4,03	23,7	0,04	0,35	disease	0,85	disease	0,92	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,9	low_impact	-3,54	medium_impact	0,04	high_impact	2,94	0,43	0,8	44,23	9,18	N	0,34	N	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11948	11948	G	T	MI.18819	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1189	397	G	W	Gga/Tga	-3,42	0	0	probably_damaging	1	neutral	0,18	neutral	2,1	deleterious	-5,76	deleterious	-7,21	high_impact	4,11	neutral	0,67	damaging	0,11	deleterious	4,5	24,3	0,08	0,35	disease	0,62	disease	0,93	disease	0,66	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,54	medium_impact	-0,17	high_impact	2,94	0,16	0,8	44,23	9,18	N	0,33	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5906	5906	G	C	MI.1882	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	3	1	M	I	atG/atC	5,68	1	0	possibly_damaging	0,84	deleterious	0	neutral	3,06	neutral	0,85	neutral	-0,14	NA	NA	damaging	0,55	damaging	0,13	deleterious	3,23	22,8	0,48	0,55	neutral	0,27	neutral	0,24	neutral	0,35	neutral	0,31	4	deleterious	1	neutral	0,08	deleterious	3	deleterious	0,63	NA	NA	NA	NA	NA	NA	0,51	0,9	3,12	6,73	P	0,62	P	0,85	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11949	11949	G	C	MI.18820	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1190	397	G	A	gGa/gCa	9,01	1	0	probably_damaging	1	neutral	0,52	neutral	2,25	neutral	-0,96	deleterious	-5,16	medium_impact	2,17	neutral	0,79	neutral	0,59	deleterious	3,15	22,6	0,19	0,45	neutral	0,45	disease	0,67	neutral	0,34	neutral	0,47	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,22	medium_impact	1,02	0,36	0,8	44,23	9,18	N	0,51	P	0,45	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11949	11949	G	A	MI.18821	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1190	397	G	E	gGa/gAa	9,01	1	0	probably_damaging	1	neutral	0,27	neutral	2,07	deleterious	-4,82	deleterious	-7,11	high_impact	3,76	neutral	0,67	damaging	0,12	deleterious	3,99	23,6	0,05	0,35	disease	0,88	disease	0,92	disease	0,72	disease	0,82	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,88	low_impact	-3,54	medium_impact	-0,04	high_impact	2,59	0,2	0,8	44,23	9,18	P	0,62	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11949	11949	G	T	MI.18822	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1190	397	G	V	gGa/gTa	9,01	1	0	probably_damaging	1	neutral	0,52	neutral	2,2	neutral	0,88	deleterious	-7,98	medium_impact	3,13	neutral	0,67	damaging	0,11	deleterious	3,83	23,4	0,09	0,4	neutral	0,47	disease	0,87	disease	0,52	disease	0,63	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	0,22	medium_impact	1,97	0,16	0,8	44,23	9,18	N	0,49	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11951	11951	C	T	MI.18823	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1192	398	L	F	Ctc/Ttc	-2,04	0	0	benign	0,01	neutral	0,21	neutral	2,03	neutral	-1,89	neutral	-2,19	low_impact	1,82	neutral	0,81	neutral	0,94	neutral	1,16	11,56	0,27	0,45	neutral	0,43	neutral	0,45	neutral	0,35	neutral	0,47	1	neutral	0,79	deleterious	0,6	neutral	-6	neutral	0,33	medium_impact	1,16	medium_impact	-0,12	medium_impact	0,68	0,36	0,8	10,68	15,54	N	0,44	N	0,01	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11951	11951	C	G	MI.18824	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1192	398	L	V	Ctc/Gtc	-2,04	0	0	benign	0,12	neutral	0,25	neutral	2,15	neutral	-2,14	neutral	-1,36	medium_impact	2,4	neutral	0,76	neutral	0,94	deleterious	0,32	5,87	0,27	0,45	disease	0,59	neutral	0,32	neutral	0,3	disease	0,6	2	neutral	0,71	deleterious	0,57	neutral	-3	neutral	0,17	medium_impact	0,1	medium_impact	-0,07	medium_impact	1,25	0,45	0,8	10,68	15,54	N	0,46	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11951	11951	C	A	MI.18825	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1192	398	L	I	Ctc/Atc	-2,04	0	0	benign	0,12	neutral	0,31	neutral	2,2	neutral	0,14	neutral	-0,9	medium_impact	1,95	neutral	0,76	neutral	0,99	deleterious	0,83	9,63	0,27	0,45	neutral	0,4	neutral	0,3	neutral	0,26	neutral	0,47	1	neutral	0,64	deleterious	0,6	neutral	-3	neutral	0,17	medium_impact	0,1	medium_impact	0,01	medium_impact	0,8	0,4	0,8	10,68	15,54	N	0,52	P	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11952	11952	T	C	MI.18826	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1193	398	L	P	cTc/cCc	-7,8	0	0	possibly_damaging	0,5	deleterious	0,03	neutral	1,94	neutral	-0,33	deleterious	-4,58	medium_impact	2,85	neutral	0,62	neutral	0,58	deleterious	2,14	17,09	0,05	0,35	disease	0,91	disease	0,81	disease	0,71	disease	0,76	5	neutral	0,97	neutral	0,27	deleterious	4	deleterious	0,46	medium_impact	-0,72	medium_impact	-0,64	medium_impact	1,69	0,3	0,8	10,68	15,54	N	0,33	N	0,74	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11952	11952	T	A	MI.18827	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1193	398	L	H	cTc/cAc	-7,8	0	0	possibly_damaging	0,67	deleterious	0,02	neutral	1,94	deleterious	-4,86	deleterious	-4,58	high_impact	3,82	neutral	0,72	neutral	0,51	deleterious	2,6	20,2	0,07	0,35	disease	0,91	disease	0,71	disease	0,68	disease	0,75	5	deleterious	0,98	neutral	0,18	deleterious	5	deleterious	0,57	low_impact	-1,01	medium_impact	-0,75	high_impact	2,65	0,26	0,8	10,68	15,54	N	0,4	N	0,51	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11952	11952	T	G	MI.18828	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1193	398	L	R	cTc/cGc	-7,8	0	0	benign	0,43	deleterious	0,01	neutral	1,94	deleterious	-4,32	deleterious	-3,98	high_impact	3,82	neutral	0,69	neutral	0,45	deleterious	2,39	18,78	0,04	0,35	disease	0,88	disease	0,81	disease	0,71	disease	0,78	6	deleterious	0,99	neutral	0,29	deleterious	2	deleterious	0,44	medium_impact	-0,6	medium_impact	-0,92	high_impact	2,65	0,11	0,8	10,68	15,54	N	0,35	N	0,57	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11954	11954	A	C	MI.18829	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1195	399	N	H	Aac/Cac	-12,86	0	0	probably_damaging	1	neutral	0,53	neutral	2,29	deleterious	-3,03	deleterious	-3,76	medium_impact	3,17	neutral	0,8	damaging	0,12	deleterious	3,17	22,7	0,37	0,5	disease	0,84	disease	0,59	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,77	low_impact	-3,54	medium_impact	0,23	high_impact	2,01	0,2	0,8	47,28	9,45	N	0,22	N	0,97	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5907	5907	T	A	MI.1883	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	4	2	F	I	Ttc/Atc	7,3	1	0	benign	0	neutral	0,39	neutral	2,55	deleterious	-3,32	neutral	-0,12	low_impact	1,04	neutral	0,72	neutral	0,63	deleterious	0,72	8,98	0,35	0,55	neutral	0,15	neutral	0,31	neutral	0,44	neutral	0,38	2	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,09	medium_impact	-0,14	0,44	0,9	10,14	44,98	P	0,59	P	0,41	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11954	11954	A	T	MI.18830	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1195	399	N	Y	Aac/Tac	-12,86	0	0	probably_damaging	1	neutral	1	neutral	2,31	neutral	-2,94	deleterious	-5,96	medium_impact	2,82	neutral	0,74	damaging	0,11	deleterious	3,73	23,3	0,13	0,4	disease	0,74	disease	0,66	disease	0,61	disease	0,71	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,77	low_impact	-3,54	high_impact	1,88	medium_impact	1,66	0,26	0,8	47,28	9,45	N	0,16	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11954	11954	A	G	MI.18831	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1195	399	N	D	Aac/Gac	-12,86	0	0	probably_damaging	1	neutral	0,2	neutral	2,29	neutral	-2,4	deleterious	-3,47	medium_impact	3,17	neutral	0,71	damaging	0,12	deleterious	3,86	23,5	0,46	0,55	disease	0,88	disease	0,61	disease	0,65	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,14	high_impact	2,01	0,25	0,8	47,28	9,45	N	0,31	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11955	11955	A	T	MI.18832	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1196	399	N	I	aAc/aTc	3,25	0,99	0	probably_damaging	1	neutral	0,4	neutral	2,39	neutral	1,66	deleterious	-6,88	low_impact	1,88	neutral	0,71	damaging	0,14	deleterious	4,08	23,7	0,15	0,45	neutral	0,48	disease	0,68	disease	0,58	disease	0,53	1	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,72	low_impact	-3,54	medium_impact	0,1	medium_impact	0,73	0,2	0,8	47,28	9,45	N	0,4	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11955	11955	A	G	MI.18833	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1196	399	N	S	aAc/aGc	3,25	0,99	0	probably_damaging	1	neutral	0,4	neutral	2,38	neutral	0,35	deleterious	-3,17	low_impact	1,31	neutral	0,75	neutral	0,34	deleterious	3,13	22,6	0,46	0,55	neutral	0,49	neutral	0,42	neutral	0,38	neutral	0,42	2	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,1	medium_impact	0,17	0,27	0,8	47,28	9,45	N	0,48	N	0,79	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11955	11955	A	C	MI.18834	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1196	399	N	T	aAc/aCc	3,25	0,99	0	probably_damaging	1	neutral	0,39	neutral	2,46	neutral	-0,19	deleterious	-4,39	low_impact	1,03	neutral	0,74	neutral	0,3	deleterious	3,45	23	0,3	0,45	neutral	0,41	neutral	0,43	neutral	0,36	neutral	0,47	1	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,67	low_impact	-3,54	medium_impact	0,09	medium_impact	-0,11	0,25	0,8	47,28	9,45	N	0,44	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11956	11956	C	G	MI.18835	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1197	399	N	K	aaC/aaG	3,48	0,99	0	probably_damaging	1	neutral	0,29	neutral	2,3	neutral	-0,23	deleterious	-4,39	medium_impact	2,82	neutral	0,7	damaging	0,11	deleterious	4,01	23,6	0,38	0,5	disease	0,78	disease	0,7	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,02	medium_impact	1,66	0,32	0,8	47,28	9,45	N	0,49	N	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11956	11956	C	A	MI.18836	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1197	399	N	K	aaC/aaA	3,48	0,99	0	probably_damaging	1	neutral	0,29	neutral	2,3	neutral	-0,23	deleterious	-4,39	medium_impact	2,82	neutral	0,7	damaging	0,11	deleterious	4,53	24,3	0,38	0,5	disease	0,78	disease	0,7	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,79	low_impact	-3,54	medium_impact	-0,02	medium_impact	1,66	0,32	0,8	47,28	9,45	N	0,49	N	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11957	11957	A	T	MI.18837	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1198	400	M	L	Ata/Tta	-4,81	0	0	benign	0,02	neutral	0,44	neutral	2,47	neutral	2,47	neutral	-1,15	medium_impact	2	neutral	0,69	neutral	0,73	neutral	1,36	12,56	0,26	0,45	disease	0,58	disease	0,63	neutral	0,41	disease	0,51	0	neutral	0,54	deleterious	0,71	neutral	-3	neutral	0,18	medium_impact	0,87	medium_impact	0,14	medium_impact	0,85	0,27	0,8	21,13	19,97	N	0,39	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11957	11957	A	G	MI.18838	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1198	400	M	V	Ata/Gta	-4,81	0	0	benign	0	neutral	0,37	neutral	2,38	neutral	2,12	neutral	-0,88	low_impact	1,46	neutral	0,79	neutral	0,98	neutral	-0,56	0,15	0,25	0,45	neutral	0,43	neutral	0,46	neutral	0,4	neutral	0,46	1	neutral	0,63	deleterious	0,69	neutral	-6	neutral	0,15	high_impact	2,1	medium_impact	0,07	medium_impact	0,32	0,26	0,8	21,13	19,97	N	0,39	N	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11957	11957	A	C	MI.18839	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1198	400	M	L	Ata/Cta	-4,81	0	0	benign	0,02	neutral	0,44	neutral	2,47	neutral	2,47	neutral	-1,15	medium_impact	2	neutral	0,69	neutral	0,73	neutral	1,28	12,17	0,26	0,45	disease	0,58	disease	0,63	neutral	0,41	disease	0,51	0	neutral	0,54	deleterious	0,71	neutral	-3	neutral	0,18	medium_impact	0,87	medium_impact	0,14	medium_impact	0,85	0,27	0,8	21,13	19,97	N	0,38	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5907	5907	T	C	MI.1884	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	4	2	F	L	Ttc/Ctc	7,3	1	0	benign	0	neutral	0,64	neutral	2,62	neutral	-2,25	neutral	-0,08	neutral_impact	0,49	neutral	0,77	neutral	0,74	neutral	-0,28	0,76	0,46	0,55	neutral	0,2	neutral	0,17	neutral	0,17	neutral	0,17	7	neutral	0,36	deleterious	0,82	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,33	medium_impact	-0,65	0,42	0,9	10,14	44,98	N	0,52	P	0,01	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11958	11958	T	C	MI.18840	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1199	400	M	T	aTa/aCa	3,25	0,19	0	benign	0,01	neutral	1	neutral	2,4	neutral	2,84	neutral	-0,9	neutral_impact	0,62	neutral	0,66	neutral	0,94	neutral	-1,58	0	0,11	0,4	disease	0,57	neutral	0,09	neutral	0,34	neutral	0,29	4	neutral	0,01	deleterious	1	neutral	-6	neutral	0,17	medium_impact	1,16	high_impact	1,88	medium_impact	-0,51	0,18	0,8	21,13	19,97	N	0,39	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11958	11958	T	A	MI.18841	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1199	400	M	K	aTa/aAa	3,25	0,19	0	benign	0,16	neutral	0,11	neutral	2,23	neutral	-0,93	deleterious	-3,18	medium_impact	3,32	neutral	0,67	neutral	0,41	deleterious	2,18	17,39	0,06	0,35	disease	0,84	disease	0,76	disease	0,7	disease	0,8	6	neutral	0,87	deleterious	0,48	neutral	-3	neutral	0,38	medium_impact	-0,04	medium_impact	-0,31	high_impact	2,16	0,23	0,8	21,13	19,97	N	0,38	N	0,89	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11959	11959	A	C	MI.18842	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1200	400	M	I	atA/atC	1,41	0,16	0,01	benign	0,05	neutral	0,54	neutral	2,36	neutral	1,1	neutral	-1,19	low_impact	1,7	neutral	0,77	neutral	0,99	deleterious	0,11	3,69	0,26	0,45	neutral	0,4	neutral	0,43	neutral	0,38	neutral	0,46	1	neutral	0,41	deleterious	0,75	neutral	-6	neutral	0,16	medium_impact	0,48	medium_impact	0,24	medium_impact	0,56	0,23	0,8	21,13	19,97	N	0,35	N	0,11	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11959	11959	A	T	MI.18843	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1200	400	M	I	atA/atT	1,41	0,16	0,01	benign	0,05	neutral	0,54	neutral	2,36	neutral	1,1	neutral	-1,19	low_impact	1,7	neutral	0,77	neutral	0,99	deleterious	0,17	4,37	0,26	0,45	neutral	0,4	neutral	0,43	neutral	0,38	neutral	0,46	1	neutral	0,41	deleterious	0,75	neutral	-6	neutral	0,16	medium_impact	0,48	medium_impact	0,24	medium_impact	0,56	0,23	0,8	21,13	19,97	N	0,35	N	0,11	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11960	11960	C	G	MI.18844	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1201	401	L	V	Cta/Gta	-9,18	0	0	probably_damaging	1	neutral	0,37	neutral	2,27	neutral	0,93	neutral	-1,26	medium_impact	2,15	neutral	0,84	neutral	0,96	deleterious	2,19	17,45	0,33	0,5	disease	0,56	neutral	0,31	neutral	0,28	disease	0,59	2	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,68	low_impact	-3,54	medium_impact	0,07	medium_impact	1	0,48	0,8	20,7	22,92	N	0,39	N	0,07	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11960	11960	C	A	MI.18845	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1201	401	L	M	Cta/Ata	-9,18	0	0	probably_damaging	1	neutral	0,09	neutral	2,08	neutral	-2,64	neutral	-1,13	medium_impact	2,6	neutral	0,82	neutral	0,79	deleterious	2,68	20,7	0,24	0,45	disease	0,72	neutral	0,45	neutral	0,32	disease	0,63	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,71	low_impact	-3,54	medium_impact	-0,36	medium_impact	1,45	0,49	0,8	20,7	22,92	N	0,44	N	0,45	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11961	11961	T	A	MI.18846	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1202	401	L	Q	cTa/cAa	-0,66	0	0	probably_damaging	1	deleterious	0	neutral	2,04	deleterious	-5,67	deleterious	-4,47	high_impact	3,98	neutral	0,72	neutral	0,53	deleterious	4,43	24,2	0,06	0,35	disease	0,93	disease	0,73	disease	0,59	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	2,81	0,26	0,8	20,7	22,92	N	0,41	N	0,86	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11961	11961	T	G	MI.18847	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1202	401	L	R	cTa/cGa	-0,66	0	0	probably_damaging	1	deleterious	0	neutral	2,05	deleterious	-5,49	deleterious	-4,67	high_impact	3,98	neutral	0,65	neutral	0,45	deleterious	4,27	24	0,04	0,35	disease	0,92	disease	0,86	disease	0,72	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	2,81	0,19	0,8	20,7	22,92	N	0,37	N	0,88	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11961	11961	T	C	MI.18848	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1202	401	L	P	cTa/cCa	-0,66	0	0	probably_damaging	1	deleterious	0	neutral	2,04	deleterious	-6,05	deleterious	-5,17	high_impact	3,98	neutral	0,65	neutral	0,43	deleterious	4,02	23,6	0,04	0,35	disease	0,94	disease	0,83	disease	0,73	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	2,81	0,23	0,8	20,7	22,92	N	0,34	N	0,94	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11963	11963	G	C	MI.18849	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1204	402	V	L	Gtc/Ctc	-0,66	0	0,02	benign	0,01	neutral	0,84	neutral	2,54	neutral	1,21	neutral	-0,66	neutral_impact	-1,38	neutral	0,68	neutral	0,95	deleterious	0,53	7,69	0,19	0,45	disease	0,51	neutral	0,33	neutral	0,24	neutral	0,34	3	neutral	0,13	deleterious	0,92	neutral	-6	neutral	0,14	medium_impact	1,16	medium_impact	0,61	low_impact	-2,49	0,19	0,8	34,2	8,3	N	0,32	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5907	5907	T	G	MI.1885	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	4	2	F	V	Ttc/Gtc	7,3	1	0	benign	0,02	neutral	0,5	neutral	2,55	deleterious	-3,28	neutral	-0,14	low_impact	1,04	neutral	0,78	neutral	0,62	deleterious	0,21	4,74	0,35	0,55	neutral	0,14	neutral	0,31	neutral	0,45	neutral	0,38	2	neutral	0,48	deleterious	0,74	neutral	-6	neutral	0,06	medium_impact	0,83	medium_impact	0,19	medium_impact	-0,14	0,33	0,9	10,14	44,98	P	0,55	P	0,56	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11963	11963	G	A	MI.18850	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1204	402	V	I	Gtc/Atc	-0,66	0	0,02	benign	0	neutral	1	neutral	2,32	neutral	1,01	neutral	0,74	neutral_impact	-2,9	neutral	0,68	neutral	0,95	neutral	-0,95	0,02	0,24	0,45	neutral	0,42	neutral	0,05	neutral	0,15	neutral	0,24	5	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,1	high_impact	1,88	low_impact	-4	0,44	0,8	34,2	8,3	N	0,33	N	0,02	polymorphism	1	0,01	rs201803948	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11963	11963	G	T	MI.18851	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1204	402	V	F	Gtc/Ttc	-0,66	0	0,02	benign	0,13	neutral	1	neutral	2,28	neutral	0,1	deleterious	-2,63	neutral_impact	-0,9	neutral	0,71	neutral	0,73	deleterious	2	16,23	0,06	0,35	disease	0,76	disease	0,58	neutral	0,23	disease	0,52	0	neutral	0,13	deleterious	0,94	neutral	-6	neutral	0,23	medium_impact	0,06	high_impact	1,88	low_impact	-2,02	0,2	0,8	34,2	8,3	N	0,18	N	0,52	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11964	11964	T	G	MI.18852	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1205	402	V	G	gTc/gGc	0,72	0,09	0	benign	0,28	neutral	0,13	neutral	2,14	deleterious	-5,7	deleterious	-6,14	low_impact	1,04	neutral	0,72	neutral	0,48	deleterious	2,02	16,33	0,05	0,35	disease	0,75	disease	0,59	disease	0,51	disease	0,55	1	neutral	0,85	neutral	0,43	neutral	-6	neutral	0,28	medium_impact	-0,33	medium_impact	-0,26	medium_impact	-0,1	0,25	0,8	34,2	8,3	N	0,38	N	0,44	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11964	11964	T	C	MI.18853	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1205	402	V	A	gTc/gCc	0,72	0,09	0	benign	0,05	deleterious	0,02	neutral	2,22	neutral	0,86	deleterious	-3,42	neutral_impact	0,7	neutral	0,74	neutral	0,72	neutral	1,78	14,87	0,12	0,4	disease	0,54	neutral	0,37	neutral	0,48	disease	0,58	2	neutral	0,98	deleterious	0,49	neutral	-2	neutral	0,17	medium_impact	0,48	medium_impact	-0,75	medium_impact	-0,43	0,06	0,8	34,2	8,3	N	0,4	N	0,31	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11964	11964	T	A	MI.18854	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1205	402	V	D	gTc/gAc	0,72	0,09	0	possibly_damaging	0,47	deleterious	0	neutral	2,12	deleterious	-6,76	deleterious	-5,4	low_impact	1,04	neutral	0,69	neutral	0,47	deleterious	2,83	21,5	0,03	0,35	disease	0,72	disease	0,79	disease	0,62	disease	0,76	5	deleterious	1	neutral	0,27	deleterious	1	neutral	0,39	medium_impact	-0,67	low_impact	-1,48	medium_impact	-0,1	0,16	0,8	34,2	8,3	N	0,35	N	0,47	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11966	11966	A	T	MI.18855	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1207	403	T	S	Aca/Tca	-6,88	0	0	probably_damaging	1	neutral	1	neutral	1,94	neutral	0,81	deleterious	-3,71	medium_impact	2,44	neutral	0,7	damaging	0,2	deleterious	3,33	22,9	0,35	0,5	disease	0,64	neutral	0,45	neutral	0,46	disease	0,56	1	deleterious	0,99	deleterious	0,5	deleterious	1	deleterious	0,72	low_impact	-3,54	high_impact	1,88	medium_impact	1,29	0,6	0,8	45,53	9,79	N	0,21	N	0,84	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11966	11966	A	C	MI.18856	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1207	403	T	P	Aca/Cca	-6,88	0	0	probably_damaging	1	deleterious	0	neutral	1,79	deleterious	-4,49	deleterious	-5,56	high_impact	3,82	neutral	0,68	damaging	0,19	deleterious	3,55	23,1	0,05	0,35	disease	0,53	disease	0,86	disease	0,75	disease	0,78	6	deleterious	1	deleterious	0	deleterious	6	deleterious	0,79	low_impact	-3,54	low_impact	-1,48	high_impact	2,65	0,38	0,8	45,53	9,79	N	0,34	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11966	11966	A	G	MI.18857	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1207	403	T	A	Aca/Gca	-6,88	0	0	probably_damaging	1	neutral	0,16	neutral	1,93	neutral	0,3	deleterious	-4,63	medium_impact	2,75	neutral	0,71	damaging	0,2	deleterious	3,53	23,1	0,19	0,45	disease	0,69	disease	0,61	disease	0,62	disease	0,54	1	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	-0,2	medium_impact	1,6	0,42	0,8	45,53	9,79	N	0,3	N	0,68	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11967	11967	C	T	MI.18858	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1208	403	T	M	aCa/aTa	6,7	1	0	probably_damaging	1	deleterious	0,02	neutral	1,8	deleterious	-4,6	deleterious	-5,56	high_impact	4,17	neutral	0,72	damaging	0,15	deleterious	4,14	23,8	0,09	0,35	disease	0,5	disease	0,83	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,72	low_impact	-3,54	medium_impact	-0,75	high_impact	3	0,57	0,8	45,53	9,79	P	0,59	P	0,92	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11967	11967	C	A	MI.18859	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1208	403	T	K	aCa/aAa	6,7	1	0	probably_damaging	1	deleterious	0	neutral	1,82	neutral	-0,84	deleterious	-5,56	high_impact	4,17	neutral	0,71	damaging	0,13	deleterious	4,56	24,4	0,08	0,35	disease	0,74	disease	0,89	disease	0,79	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3	0,41	0,8	45,53	9,79	P	0,65	P	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5908	5908	T	C	MI.1886	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	5	2	F	S	tTc/tCc	1,28	0,99	0	benign	0,12	neutral	0,4	neutral	2,52	deleterious	-4,24	neutral	-0,17	neutral_impact	0,69	neutral	0,71	neutral	0,73	deleterious	0,52	7,56	0,32	0,55	neutral	0,3	neutral	0,31	neutral	0,25	neutral	0,38	2	neutral	0,54	deleterious	0,64	neutral	-6	neutral	0,16	medium_impact	0,06	medium_impact	0,1	medium_impact	-0,46	0,25	0,9	10,14	44,98	N	0,52	P	0,75	disease_causing	0,82	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11969	11969	G	C	MI.18860	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1210	404	A	P	Gcc/Ccc	-3,65	0	0,02	possibly_damaging	0,87	deleterious	0,01	neutral	1,73	deleterious	-6,84	deleterious	-4,26	high_impact	4,11	neutral	0,7	neutral	0,4	deleterious	2,26	17,9	0,03	0,35	disease	0,88	disease	0,87	disease	0,79	disease	0,85	7	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,65	low_impact	-1,49	medium_impact	-0,92	high_impact	2,94	0,47	0,8	18,95	21,95	N	0,46	N	0,93	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11969	11969	G	A	MI.18861	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1210	404	A	T	Gcc/Acc	-3,65	0	0,02	benign	0,04	neutral	0,05	neutral	1,76	deleterious	-4,02	deleterious	-3,24	medium_impact	1,99	damaging	0,54	neutral	0,64	deleterious	2,35	18,49	0,1	0,4	disease	0,69	disease	0,75	neutral	0,49	disease	0,51	0	neutral	0,95	deleterious	0,51	neutral	-3	neutral	0,26	medium_impact	0,58	medium_impact	-0,52	medium_impact	0,84	0,63	0,8	18,95	21,95	N	0,42	N	0,16	polymorphism	1	0,12	rs28359169	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11969	11969	G	T	MI.18862	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1210	404	A	S	Gcc/Tcc	-3,65	0	0,02	possibly_damaging	0,48	neutral	0,12	neutral	1,85	deleterious	-3,25	neutral	-2,37	medium_impact	2,79	neutral	0,62	neutral	0,67	deleterious	1,86	15,36	0,19	0,45	neutral	0,4	disease	0,79	disease	0,6	disease	0,62	2	neutral	0,87	neutral	0,32	NA	0	neutral	0,27	medium_impact	-0,69	medium_impact	-0,28	medium_impact	1,63	0,44	0,8	18,95	21,95	N	0,39	N	0,59	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11970	11970	C	A	MI.18863	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1211	404	A	D	gCc/gAc	2,79	0,78	0	possibly_damaging	0,83	deleterious	0	neutral	1,71	deleterious	-4,11	deleterious	-5,03	high_impact	4,11	neutral	0,75	neutral	0,37	deleterious	2,99	22,2	0,03	0,35	disease	0,89	disease	0,91	disease	0,77	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	5	deleterious	0,56	low_impact	-1,37	low_impact	-1,48	high_impact	2,94	0,28	0,8	18,95	21,95	P	0,51	P	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11970	11970	C	T	MI.18864	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1211	404	A	V	gCc/gTc	2,79	0,78	0	possibly_damaging	0,48	deleterious	0,02	neutral	1,8	deleterious	-3,11	deleterious	-3,3	medium_impact	3,42	neutral	0,65	neutral	0,54	deleterious	2,59	20,2	0,09	0,35	neutral	0,47	disease	0,81	disease	0,6	disease	0,62	2	neutral	0,98	neutral	0,27	deleterious	4	neutral	0,31	medium_impact	-0,69	medium_impact	-0,75	high_impact	2,26	0,69	0,85	18,95	21,95	N	0,43	N	0,49	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11970	11970	C	G	MI.18865	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1211	404	A	G	gCc/gGc	2,79	0,78	0	possibly_damaging	0,48	neutral	0,15	neutral	1,75	deleterious	-4,67	deleterious	-3,18	medium_impact	3,07	neutral	0,64	neutral	0,76	deleterious	2,16	17,25	0,18	0,45	disease	0,55	disease	0,75	disease	0,67	disease	0,53	1	neutral	0,83	neutral	0,34	NA	0	neutral	0,3	medium_impact	-0,69	medium_impact	-0,22	medium_impact	1,91	0,54	0,8	18,95	21,95	N	0,45	N	0,17	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11972	11972	C	G	MI.18866	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1213	405	L	V	Cta/Gta	-8,72	0	0	possibly_damaging	0,44	neutral	0,58	neutral	2,27	neutral	-2,22	neutral	-1,18	low_impact	1,49	neutral	0,75	damaging	0,26	deleterious	2,03	16,41	0,33	0,5	disease	0,67	neutral	0,25	neutral	0,23	disease	0,54	1	neutral	0,41	deleterious	0,57	neutral	-3	deleterious	0,69	medium_impact	-0,62	medium_impact	0,28	medium_impact	0,35	0,45	0,8	21,35	18,83	N	0,26	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11972	11972	C	A	MI.18867	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1213	405	L	M	Cta/Ata	-8,72	0	0	probably_damaging	0,94	neutral	0,24	neutral	2,13	deleterious	-5,05	neutral	-0,61	low_impact	1,59	neutral	0,8	neutral	0,9	deleterious	2,63	20,4	0,25	0,45	disease	0,69	neutral	0,22	neutral	0,23	neutral	0,47	1	neutral	0,96	neutral	0,15	neutral	-2	deleterious	0,68	low_impact	-1,84	medium_impact	-0,08	medium_impact	0,45	0,38	0,8	21,35	18,83	N	0,42	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11973	11973	T	C	MI.18868	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1214	405	L	P	cTa/cCa	-1,35	0	0	probably_damaging	0,98	neutral	0,2	neutral	2,08	deleterious	-6,56	deleterious	-3,59	medium_impact	3,12	neutral	0,72	damaging	0,11	deleterious	2,68	20,7	0,02	0,35	neutral	0,45	disease	0,78	disease	0,57	disease	0,73	5	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,75	low_impact	-2,31	medium_impact	-0,14	medium_impact	1,96	0,26	0,8	21,35	18,83	N	0,31	N	0,87	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11973	11973	T	A	MI.18869	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1214	405	L	Q	cTa/cAa	-1,35	0	0	probably_damaging	0,98	neutral	0,18	neutral	2,08	deleterious	-6,18	deleterious	-2,88	medium_impact	3,12	neutral	0,7	damaging	0,12	deleterious	2,94	22	0,04	0,35	disease	0,85	disease	0,54	neutral	0,4	disease	0,6	2	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,79	low_impact	-2,31	medium_impact	-0,17	medium_impact	1,96	0,29	0,8	21,35	18,83	N	0,33	N	0,9	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5908	5908	T	G	MI.1887	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	5	2	F	C	tTc/tGc	1,28	0,99	0	benign	0,38	neutral	0,17	neutral	2,49	deleterious	-5,89	neutral	-0,21	low_impact	1,04	neutral	0,63	neutral	0,58	neutral	1	10,68	0,28	0,55	neutral	0,49	neutral	0,43	neutral	0,45	neutral	0,4	2	neutral	0,8	neutral	0,4	neutral	-6	deleterious	0,44	medium_impact	-0,56	medium_impact	-0,19	medium_impact	-0,14	0,2	0,9	10,14	44,98	P	0,53	P	0,61	disease_causing	0,87	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11973	11973	T	G	MI.18870	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1214	405	L	R	cTa/cGa	-1,35	0	0	probably_damaging	0,98	neutral	0,21	neutral	2,09	deleterious	-6	deleterious	-3,11	medium_impact	3,12	neutral	0,7	damaging	0,09	deleterious	3,07	22,4	0,03	0,35	disease	0,88	disease	0,77	disease	0,54	disease	0,73	5	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,86	low_impact	-2,31	medium_impact	-0,12	medium_impact	1,96	0,28	0,8	21,35	18,83	N	0,27	N	0,97	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11975	11975	T	A	MI.18871	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1216	406	Y	N	Tac/Aac	-13,78	0	0	probably_damaging	1	deleterious	0	neutral	1,59	deleterious	-7,21	deleterious	-8,33	high_impact	4,23	damaging	0,58	damaging	0,14	deleterious	4,06	23,7	0,06	0,35	disease	0,87	disease	0,87	disease	0,78	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,06	0,19	0,8	47,28	9,59	N	0,41	N	1	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11975	11975	T	G	MI.18872	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1216	406	Y	D	Tac/Gac	-13,78	0	0	probably_damaging	1	deleterious	0	neutral	1,57	deleterious	-8,09	deleterious	-9,26	high_impact	4,23	neutral	0,67	damaging	0,13	deleterious	3,98	23,6	0,04	0,35	disease	0,92	disease	0,89	disease	0,84	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,06	0,15	0,8	47,28	9,59	N	0,42	N	0,99	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11975	11975	T	C	MI.18873	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1216	406	Y	H	Tac/Cac	-13,78	0	0	probably_damaging	1	deleterious	0	neutral	1,58	deleterious	-7,48	deleterious	-4,62	high_impact	4,23	damaging	0,58	damaging	0,13	deleterious	3,61	23,2	0,11	0,4	disease	0,76	disease	0,84	disease	0,85	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,54	low_impact	-1,48	high_impact	3,06	0,2	0,8	47,28	9,59	N	0,38	N	0,97	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11976	11976	A	G	MI.18874	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1217	406	Y	C	tAc/tGc	7,4	1	0	probably_damaging	1	deleterious	0	neutral	1,58	deleterious	-5,13	deleterious	-8,34	high_impact	4,23	damaging	0,6	damaging	0,11	deleterious	3,48	23,1	0,06	0,35	disease	0,87	disease	0,9	disease	0,82	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,54	low_impact	-1,48	high_impact	3,06	0,13	0,8	47,28	9,59	P	0,64	P	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11976	11976	A	T	MI.18875	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1217	406	Y	F	tAc/tTc	7,4	1	0	probably_damaging	1	neutral	0,09	neutral	1,67	neutral	-2,57	deleterious	-3,71	high_impact	3,54	neutral	0,6	damaging	0,17	deleterious	3,33	22,9	0,16	0,45	disease	0,57	disease	0,82	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	-0,36	high_impact	2,38	0,28	0,8	47,28	9,59	P	0,63	P	0,79	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11976	11976	A	C	MI.18876	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1217	406	Y	S	tAc/tCc	7,4	1	0	probably_damaging	1	deleterious	0,01	neutral	1,62	neutral	-2,95	deleterious	-8,33	high_impact	4,23	neutral	0,61	damaging	0,16	deleterious	3,7	23,3	0,06	0,35	disease	0,75	disease	0,87	disease	0,77	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,54	medium_impact	-0,92	high_impact	3,06	0,2	0,8	47,28	9,59	P	0,67	P	0,96	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11978	11978	T	A	MI.18877	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1219	407	S	T	Tcc/Acc	-1,12	0	0	probably_damaging	1	neutral	0,32	neutral	2,1	neutral	-2,9	neutral	-1,23	low_impact	1,68	neutral	0,75	neutral	0,97	deleterious	2,74	21	0,32	0,5	disease	0,66	neutral	0,21	neutral	0,44	neutral	0,47	1	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,69	low_impact	-3,54	medium_impact	0,02	medium_impact	0,54	0,61	0,8	38,34	8,54	N	0,45	N	0,13	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11978	11978	T	C	MI.18878	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1219	407	S	P	Tcc/Ccc	-1,12	0	0	probably_damaging	1	deleterious	0,01	neutral	1,98	deleterious	-6,17	deleterious	-3,96	high_impact	4,07	damaging	0,56	neutral	0,4	deleterious	4,11	23,7	0,04	0,35	disease	0,67	disease	0,89	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,54	medium_impact	-0,92	high_impact	2,9	0,37	0,8	38,34	8,54	N	0,41	N	0,93	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11978	11978	T	G	MI.18879	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1219	407	S	A	Tcc/Gcc	-1,12	0	0	probably_damaging	0,99	deleterious	0	neutral	2,11	neutral	-2,69	neutral	-2,33	high_impact	4,07	neutral	0,69	neutral	0,56	deleterious	3,72	23,3	0,26	0,45	neutral	0,48	disease	0,63	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,67	low_impact	-2,59	low_impact	-1,48	high_impact	2,9	0,44	0,8	38,34	8,54	N	0,48	N	0,42	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5908	5908	T	A	MI.1888	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	5	2	F	Y	tTc/tAc	1,28	0,99	0	benign	0,02	neutral	1	neutral	2,69	neutral	-1,89	neutral	-0,02	low_impact	1,04	neutral	0,72	neutral	0,74	neutral	-0,59	0,13	0,35	0,55	neutral	0,31	neutral	0,1	neutral	0,13	neutral	0,15	7	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,09	medium_impact	0,83	high_impact	1,86	medium_impact	-0,14	0,34	0,9	10,14	44,98	N	0,41	N	0,38	polymorphism	0,64	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11979	11979	C	G	MI.18880	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1220	407	S	C	tCc/tGc	-0,2	0	0	probably_damaging	1	neutral	0,05	neutral	1,98	deleterious	-5,96	deleterious	-3,96	medium_impact	3,26	neutral	0,63	neutral	0,39	deleterious	3,72	23,3	0,06	0,35	disease	0,92	disease	0,85	disease	0,67	disease	0,81	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,52	high_impact	2,1	0,31	0,8	38,34	8,54	N	0,32	N	0,49	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11979	11979	C	A	MI.18881	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1220	407	S	Y	tCc/tAc	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	2,05	neutral	0,17	deleterious	-4,87	high_impact	3,72	neutral	0,69	neutral	0,43	deleterious	4,17	23,8	0,05	0,35	disease	0,83	disease	0,87	disease	0,7	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,55	0,32	0,8	38,34	8,54	N	0,35	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11979	11979	C	T	MI.18882	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1220	407	S	F	tCc/tTc	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	2,04	deleterious	-4,64	deleterious	-4,88	high_impact	4,07	neutral	0,61	neutral	0,43	deleterious	4,37	24,1	0,04	0,35	neutral	0,39	disease	0,89	disease	0,7	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,54	low_impact	-1,48	high_impact	2,9	0,23	0,8	38,34	8,54	N	0,4	N	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11981	11981	C	G	MI.18883	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1222	408	L	V	Ctc/Gtc	-4,58	0	0	benign	0,21	neutral	0,05	neutral	1,94	deleterious	-3,03	deleterious	-2,61	high_impact	4,18	damaging	0,56	neutral	0,54	deleterious	3,52	23,1	0,25	0,45	disease	0,81	disease	0,6	disease	0,64	disease	0,69	4	neutral	0,94	neutral	0,42	neutral	-2	deleterious	0,78	medium_impact	-0,18	medium_impact	-0,52	high_impact	3,01	0,59	0,8	19,39	22,54	N	0,43	N	0,48	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11981	11981	C	A	MI.18884	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1222	408	L	I	Ctc/Atc	-4,58	0	0	benign	0,05	neutral	0,28	neutral	1,95	deleterious	-4,44	neutral	-1,7	medium_impact	3,04	damaging	0,58	neutral	0,66	deleterious	4,13	23,8	0,3	0,45	disease	0,63	disease	0,6	disease	0,53	neutral	0,48	0	neutral	0,7	deleterious	0,62	neutral	-3	deleterious	0,76	medium_impact	0,48	medium_impact	-0,03	medium_impact	1,88	0,62	0,8	19,39	22,54	N	0,38	N	0,48	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11981	11981	C	T	MI.18885	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1222	408	L	F	Ctc/Ttc	-4,58	0	0	possibly_damaging	0,8	deleterious	0,03	neutral	1,98	neutral	-2,84	deleterious	-3,34	high_impact	3,84	damaging	0,54	neutral	0,62	deleterious	4,04	23,7	0,19	0,45	disease	0,56	disease	0,72	disease	0,56	disease	0,58	2	deleterious	0,98	neutral	0,12	deleterious	5	deleterious	0,78	low_impact	-1,28	medium_impact	-0,64	high_impact	2,67	0,54	0,8	19,39	22,54	N	0,44	N	0,72	polymorphism	1	0,11	rs386829143	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11982	11982	T	A	MI.18886	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1223	408	L	H	cTc/cAc	-0,2	0	0	probably_damaging	0,94	deleterious	0	neutral	1,81	deleterious	-7,49	deleterious	-6,22	high_impact	4,18	damaging	0,54	neutral	0,45	deleterious	4,19	23,8	0,03	0,35	disease	0,66	disease	0,81	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,81	low_impact	-1,84	low_impact	-1,48	high_impact	3,01	0,45	0,8	19,39	22,54	N	0,4	N	0,83	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11982	11982	T	G	MI.18887	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1223	408	L	R	cTc/cGc	-0,2	0	0	possibly_damaging	0,84	deleterious	0	neutral	1,82	deleterious	-3,11	deleterious	-5,41	high_impact	4,18	damaging	0,56	neutral	0,44	deleterious	4,3	24	0,01	0,35	disease	0,75	disease	0,89	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,08	deleterious	5	deleterious	0,88	low_impact	-1,39	low_impact	-1,48	high_impact	3,01	0,16	0,8	19,39	22,54	N	0,43	N	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11982	11982	T	C	MI.18888	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1223	408	L	P	cTc/cCc	-0,2	0	0	probably_damaging	0,94	deleterious	0	neutral	1,81	deleterious	-3,09	deleterious	-6,31	high_impact	4,18	damaging	0,56	neutral	0,51	deleterious	3,97	23,6	0,01	0,35	disease	0,52	disease	0,82	disease	0,76	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,82	low_impact	-1,84	low_impact	-1,48	high_impact	3,01	0,51	0,8	19,39	22,54	N	0,41	N	0,87	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11984	11984	T	G	MI.18889	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1225	409	Y	D	Tac/Gac	-20	0	0	possibly_damaging	0,6	deleterious	0	neutral	2,13	deleterious	-3,55	deleterious	-7,88	high_impact	3,56	neutral	0,7	neutral	0,41	deleterious	4	23,6	0,03	0,35	disease	0,53	disease	0,9	disease	0,77	disease	0,81	6	deleterious	1	neutral	0,2	deleterious	5	deleterious	0,79	medium_impact	-0,88	low_impact	-1,48	high_impact	2,4	0,14	0,8	25,05	18,83	N	0,46	N	1	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5909	5909	C	G	MI.1889	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	6	2	F	L	ttC/ttG	1,98	0,98	0	benign	0	neutral	0,64	neutral	2,62	neutral	-2,25	neutral	-0,08	neutral_impact	0,49	neutral	0,77	neutral	0,74	deleterious	0,03	2,92	0,46	0,55	neutral	0,2	neutral	0,17	neutral	0,17	neutral	0,17	7	neutral	0,36	deleterious	0,82	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,33	medium_impact	-0,65	0,42	0,9	10,14	44,98	N	0,46	N	0,01	polymorphism	0,85	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11984	11984	T	C	MI.18890	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1225	409	Y	H	Tac/Cac	-20	0	0	benign	0,01	neutral	0,09	neutral	2,14	deleterious	-3,14	deleterious	-2,69	neutral_impact	0,1	neutral	0,75	neutral	0,83	deleterious	2,31	18,23	0,19	0,45	disease	0,67	neutral	0,47	disease	0,56	disease	0,59	2	neutral	0,91	deleterious	0,54	neutral	-6	deleterious	0,76	medium_impact	1,16	medium_impact	-0,36	low_impact	-1,03	0,17	0,8	25,05	18,83	N	0,43	N	0,42	disease_causing_automatic	0	0,12	rs200911567	Pathogenic	Leigh_syndrome	RCV000144014.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	11984	11984	T	A	MI.18891	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1225	409	Y	N	Tac/Aac	-20	0	0	possibly_damaging	0,44	deleterious	0,02	neutral	2,14	neutral	-1,08	deleterious	-6,79	medium_impact	2,87	neutral	0,7	neutral	0,65	deleterious	4,06	23,7	0,07	0,35	neutral	0,36	disease	0,86	disease	0,65	disease	0,67	3	neutral	0,98	neutral	0,29	deleterious	4	deleterious	0,76	medium_impact	-0,62	medium_impact	-0,75	medium_impact	1,71	0,2	0,8	25,05	18,83	N	0,42	N	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11985	11985	A	C	MI.18892	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1226	409	Y	S	tAc/tCc	0,26	0	0	possibly_damaging	0,53	deleterious	0,02	neutral	2,18	neutral	0,9	deleterious	-7,07	medium_impact	3,01	neutral	0,76	neutral	0,6	deleterious	3,78	23,4	0,07	0,35	neutral	0,47	disease	0,84	disease	0,57	disease	0,65	3	neutral	0,98	neutral	0,25	deleterious	4	deleterious	0,77	medium_impact	-0,77	medium_impact	-0,75	medium_impact	1,85	0,23	0,8	25,05	18,83	N	0,36	N	0,94	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11985	11985	A	T	MI.18893	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1226	409	Y	F	tAc/tTc	0,26	0	0	possibly_damaging	0,47	neutral	0,13	neutral	2,18	neutral	-0,03	deleterious	-3,45	medium_impact	2,04	neutral	0,74	neutral	0,67	deleterious	3,57	23,1	0,3	0,45	disease	0,79	disease	0,72	disease	0,6	disease	0,61	2	neutral	0,85	neutral	0,33	NA	0	deleterious	0,8	medium_impact	-0,67	medium_impact	-0,26	medium_impact	0,89	0,31	0,8	25,05	18,83	N	0,35	N	0,68	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11985	11985	A	G	MI.18894	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1226	409	Y	C	tAc/tGc	0,26	0	0	probably_damaging	0,91	deleterious	0	neutral	2,12	deleterious	-3,06	deleterious	-7,49	high_impact	3,56	neutral	0,66	neutral	0,35	deleterious	3,64	23,2	0,06	0,35	disease	0,94	disease	0,91	disease	0,72	disease	0,84	7	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,85	low_impact	-1,66	low_impact	-1,48	high_impact	2,4	0,05	0,8	25,05	18,83	N	0,31	N	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11987	11987	A	C	MI.18895	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1228	410	M	L	Ata/Cta	-6,19	0	0	benign	0,05	neutral	1	neutral	2,45	neutral	1,81	neutral	-2,47	medium_impact	2	neutral	0,68	neutral	0,57	neutral	1,69	14,38	0,25	0,45	neutral	0,4	disease	0,58	neutral	0,48	neutral	0,44	1	neutral	0,05	deleterious	0,98	neutral	-3	deleterious	0,44	medium_impact	0,48	high_impact	1,88	medium_impact	0,85	0,26	0,8	47,71	9,29	N	0,3	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11987	11987	A	T	MI.18896	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1228	410	M	L	Ata/Tta	-6,19	0	0	benign	0,05	neutral	1	neutral	2,45	neutral	1,81	neutral	-2,47	medium_impact	2	neutral	0,68	neutral	0,57	neutral	1,73	14,56	0,25	0,45	neutral	0,4	disease	0,58	neutral	0,48	neutral	0,44	1	neutral	0,05	deleterious	0,98	neutral	-3	deleterious	0,44	medium_impact	0,48	high_impact	1,88	medium_impact	0,85	0,26	0,8	47,71	9,29	N	0,31	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11987	11987	A	G	MI.18897	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1228	410	M	V	Ata/Gta	-6,19	0	0	benign	0,07	deleterious	0,03	neutral	2,26	neutral	0,07	deleterious	-3,46	medium_impact	2,29	neutral	0,73	neutral	0,63	deleterious	2,38	18,66	0,28	0,45	disease	0,52	disease	0,74	neutral	0,48	disease	0,52	0	neutral	0,97	deleterious	0,48	deleterious	1	deleterious	0,54	medium_impact	0,34	medium_impact	-0,64	medium_impact	1,14	0,31	0,8	47,71	9,29	N	0,33	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11988	11988	T	C	MI.18898	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1229	410	M	T	aTa/aCa	5,32	1	0	benign	0,38	deleterious	0	neutral	2,18	neutral	-1,74	deleterious	-5,34	high_impact	3,68	neutral	0,69	neutral	0,58	deleterious	2,97	22,1	0,08	0,35	neutral	0,39	disease	0,81	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,7	medium_impact	-0,52	low_impact	-1,48	high_impact	2,52	0,12	0,8	47,71	9,29	P	0,51	P	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11988	11988	T	A	MI.18899	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1229	410	M	K	aTa/aAa	5,32	1	0	possibly_damaging	0,6	deleterious	0	neutral	2,13	neutral	-2,37	deleterious	-5,43	high_impact	4,03	neutral	0,68	neutral	0,45	deleterious	3,99	23,6	0,03	0,35	disease	0,8	disease	0,87	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,2	deleterious	5	deleterious	0,79	medium_impact	-0,88	low_impact	-1,48	high_impact	2,86	0,18	0,8	47,71	9,29	P	0,61	P	1	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8615	8615	T	C	MI.189	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	89	30	L	S	tTg/tCg	-1,95	0	0	probably_damaging	1	neutral	0,08	neutral	4,25	neutral	-1,51	deleterious	-5,13	medium_impact	2,8	neutral	0,79	neutral	0,52	deleterious	3,62	23,2	0,28	0,65	neutral	0,48	disease	0,65	neutral	0,28	disease	0,51	0	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	-0,31	medium_impact	1,3	0,64	0,9	17,7	14,1	N	0,36	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5909	5909	C	A	MI.1890	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	6	2	F	L	ttC/ttA	1,98	0,98	0	benign	0	neutral	0,64	neutral	2,62	neutral	-2,25	neutral	-0,08	neutral_impact	0,49	neutral	0,77	neutral	0,74	deleterious	0,37	6,32	0,46	0,55	neutral	0,2	neutral	0,17	neutral	0,17	neutral	0,17	7	neutral	0,36	deleterious	0,82	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,33	medium_impact	-0,65	0,42	0,9	10,14	44,98	N	0,46	N	0,01	polymorphism	0,85	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11989	11989	A	C	MI.18900	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1230	410	M	I	atA/atC	7,4	1	0	benign	0,01	neutral	0,15	neutral	2,3	neutral	0,32	deleterious	-3,39	medium_impact	2,01	neutral	0,69	neutral	0,63	deleterious	3,15	22,6	0,25	0,45	neutral	0,36	disease	0,75	neutral	0,45	disease	0,5	0	neutral	0,85	deleterious	0,57	neutral	-3	deleterious	0,61	medium_impact	1,16	medium_impact	-0,22	medium_impact	0,86	0,33	0,8	47,71	9,29	P	0,61	P	0,97	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11989	11989	A	T	MI.18901	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1230	410	M	I	atA/atT	7,4	1	0	benign	0,01	neutral	0,15	neutral	2,3	neutral	0,32	deleterious	-3,39	medium_impact	2,01	neutral	0,69	neutral	0,63	deleterious	3,24	22,8	0,25	0,45	neutral	0,36	disease	0,75	neutral	0,45	disease	0,5	0	neutral	0,85	deleterious	0,57	neutral	-3	deleterious	0,61	medium_impact	1,16	medium_impact	-0,22	medium_impact	0,86	0,33	0,8	47,71	9,29	P	0,61	P	0,97	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11990	11990	T	C	MI.18902	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1231	411	F	L	Ttt/Ctt	-1,12	0	0	benign	0,01	neutral	0,38	neutral	2,28	neutral	-0,06	neutral	-0,72	low_impact	1,51	neutral	0,77	neutral	0,95	deleterious	0,26	5,26	0,26	0,45	neutral	0,43	neutral	0,43	neutral	0,4	neutral	0,44	1	neutral	0,61	deleterious	0,69	neutral	-6	neutral	0,16	medium_impact	1,16	medium_impact	0,08	medium_impact	0,37	0,79	0,85	30,94	28,83	N	0,41	N	0,14	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11990	11990	T	A	MI.18903	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1231	411	F	I	Ttt/Att	-1,12	0	0	benign	0,14	neutral	0,09	neutral	2,25	neutral	-0,49	neutral	-1,5	medium_impact	3,17	neutral	0,79	neutral	0,84	neutral	1,47	13,15	0,18	0,45	neutral	0,44	disease	0,73	disease	0,54	disease	0,61	2	neutral	0,9	deleterious	0,48	neutral	-3	neutral	0,24	medium_impact	0,02	medium_impact	-0,36	high_impact	2,01	0,6	0,8	30,94	28,83	N	0,41	N	0,18	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11990	11990	T	G	MI.18904	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1231	411	F	V	Ttt/Gtt	-1,12	0	0	benign	0,22	deleterious	0,02	neutral	2,22	neutral	-0,63	neutral	-2,39	medium_impact	3,42	neutral	0,74	neutral	0,58	deleterious	2,11	16,94	0,12	0,4	disease	0,55	disease	0,79	disease	0,63	disease	0,68	4	neutral	0,98	neutral	0,4	deleterious	1	neutral	0,27	medium_impact	-0,2	medium_impact	-0,75	high_impact	2,26	0,5	0,8	30,94	28,83	N	0,37	N	0,52	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11991	11991	T	A	MI.18905	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1232	411	F	Y	tTt/tAt	-0,43	0	0	benign	0,01	neutral	1	neutral	2,3	neutral	-0,31	neutral	-1,61	low_impact	1,7	neutral	0,77	neutral	0,77	deleterious	2,54	19,74	0,16	0,45	disease	0,59	neutral	0,43	neutral	0,38	disease	0,59	2	neutral	0,01	deleterious	1	neutral	-6	neutral	0,41	medium_impact	1,16	high_impact	1,88	medium_impact	0,56	0,7	0,85	30,94	28,83	N	0,23	N	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11991	11991	T	G	MI.18906	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1232	411	F	C	tTt/tGt	-0,43	0	0	possibly_damaging	0,86	deleterious	0	neutral	2,09	deleterious	-3,59	deleterious	-3,89	high_impact	3,97	neutral	0,76	neutral	0,47	deleterious	3,86	23,5	0,04	0,35	disease	0,91	disease	0,86	disease	0,67	disease	0,8	6	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,69	low_impact	-1,46	low_impact	-1,48	high_impact	2,8	0,37	0,8	30,94	28,83	N	0,41	N	0,71	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11991	11991	T	C	MI.18907	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1232	411	F	S	tTt/tCt	-0,43	0	0	possibly_damaging	0,48	neutral	0,05	neutral	2,11	neutral	-2,38	deleterious	-4,37	high_impact	3,97	neutral	0,74	neutral	0,56	deleterious	2,63	20,4	0,04	0,35	neutral	0,43	disease	0,8	disease	0,65	disease	0,68	4	neutral	0,94	neutral	0,29	deleterious	1	deleterious	0,45	medium_impact	-0,69	medium_impact	-0,52	high_impact	2,8	0,5	0,8	30,94	28,83	N	0,52	P	0,82	polymorphism	1	0,15	.	.	.	.	.	.	COSM1132242	.	.	.	.	.	.	.	.
chrM	11992	11992	T	A	MI.18908	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1233	411	F	L	ttT/ttA	7,4	0,95	0	benign	0,01	neutral	0,38	neutral	2,28	neutral	-0,06	neutral	-0,72	low_impact	1,51	neutral	0,77	neutral	0,95	deleterious	0,67	8,65	0,26	0,45	neutral	0,43	neutral	0,43	neutral	0,4	neutral	0,44	1	neutral	0,61	deleterious	0,69	neutral	-6	neutral	0,16	medium_impact	1,16	medium_impact	0,08	medium_impact	0,37	0,79	0,85	30,94	28,83	P	0,52	P	0,14	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11992	11992	T	G	MI.18909	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1233	411	F	L	ttT/ttG	7,4	0,95	0	benign	0,01	neutral	0,38	neutral	2,28	neutral	-0,06	neutral	-0,72	low_impact	1,51	neutral	0,77	neutral	0,95	deleterious	0,56	7,86	0,26	0,45	neutral	0,43	neutral	0,43	neutral	0,4	neutral	0,44	1	neutral	0,61	deleterious	0,69	neutral	-6	neutral	0,16	medium_impact	1,16	medium_impact	0,08	medium_impact	0,37	0,79	0,85	30,94	28,83	P	0,52	P	0,14	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5910	5910	G	C	MI.1891	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	7	3	A	P	Gcc/Ccc	-0,57	0	0	benign	0,16	neutral	0,06	neutral	2,9	neutral	-2,17	neutral	-0,08	low_impact	0,9	neutral	0,65	neutral	0,8	deleterious	0,6	8,17	0,21	0,55	neutral	0,47	neutral	0,22	neutral	0,07	neutral	0,31	4	neutral	0,93	neutral	0,45	neutral	-6	neutral	0,26	medium_impact	-0,08	medium_impact	-0,47	medium_impact	-0,27	0,69	0,9	11,5	19,25	P	0,63	P	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11993	11993	A	T	MI.18910	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1234	412	T	S	Acc/Tcc	-5,5	0	0	benign	0,21	neutral	0,43	neutral	2,32	neutral	-0,42	neutral	-1,26	neutral_impact	0,8	neutral	0,69	neutral	0,99	neutral	1,51	13,34	0,24	0,45	disease	0,72	neutral	0,13	neutral	0,13	neutral	0,46	1	neutral	0,48	deleterious	0,61	neutral	-6	neutral	0,24	medium_impact	-0,18	medium_impact	0,13	medium_impact	-0,33	0,49	0,8	19,39	15,49	N	0,44	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11993	11993	A	G	MI.18911	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1234	412	T	A	Acc/Gcc	-5,5	0	0	benign	0,08	neutral	0,51	neutral	2,3	neutral	-0,76	neutral	-0,55	low_impact	1,29	neutral	0,71	neutral	0,84	neutral	1,65	14,13	0,16	0,45	disease	0,61	neutral	0,25	neutral	0,31	disease	0,54	1	neutral	0,42	deleterious	0,72	neutral	-6	neutral	0,18	medium_impact	0,28	medium_impact	0,21	medium_impact	0,15	0,26	0,8	19,39	15,49	N	0,38	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11993	11993	A	C	MI.18912	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1234	412	T	P	Acc/Ccc	-5,5	0	0	possibly_damaging	0,6	neutral	0,2	neutral	2,24	neutral	-2,71	neutral	-2,31	medium_impact	2,79	neutral	0,67	neutral	0,45	deleterious	1,81	15,03	0,06	0,35	disease	0,87	disease	0,76	disease	0,56	disease	0,79	6	neutral	0,81	neutral	0,3	NA	0	deleterious	0,55	medium_impact	-0,88	medium_impact	-0,14	medium_impact	1,63	0,32	0,8	19,39	15,49	N	0,33	N	0,82	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11994	11994	C	A	MI.18913	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1235	412	T	N	aCc/aAc	0,49	0	0	possibly_damaging	0,6	neutral	0,31	neutral	2,29	neutral	-0,5	neutral	-2,22	medium_impact	2,79	neutral	0,69	neutral	0,62	deleterious	1,92	15,71	0,24	0,45	disease	0,9	disease	0,6	neutral	0,41	disease	0,65	3	neutral	0,71	neutral	0,36	NA	0	deleterious	0,48	medium_impact	-0,88	medium_impact	0,01	medium_impact	1,63	0,41	0,8	19,39	15,49	N	0,39	N	0,67	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11994	11994	C	T	MI.18914	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1235	412	T	I	aCc/aTc	0,49	0	0	benign	0	neutral	0,4	neutral	2,29	neutral	-0,99	neutral	2,51	neutral_impact	0,02	neutral	0,75	neutral	0,98	neutral	-0,24	0,9	0,11	0,4	neutral	0,36	neutral	0,25	neutral	0,13	neutral	0,45	1	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,1	low_impact	-1,11	0,59	0,8	19,39	15,49	N	0,52	P	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	C11994T	OAT	+	-	Conflicting reports	2
chrM	11994	11994	C	G	MI.18915	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1235	412	T	S	aCc/aGc	0,49	0	0	benign	0,21	neutral	0,43	neutral	2,32	neutral	-0,42	neutral	-1,26	neutral_impact	0,8	neutral	0,69	neutral	0,99	neutral	1,73	14,55	0,24	0,45	disease	0,72	neutral	0,13	neutral	0,13	neutral	0,46	1	neutral	0,48	deleterious	0,61	neutral	-6	neutral	0,24	medium_impact	-0,18	medium_impact	0,13	medium_impact	-0,33	0,49	0,8	19,39	15,49	N	0,45	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11996	11996	A	C	MI.18916	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1237	413	T	P	Aca/Cca	-9,41	0	0	benign	0,4	neutral	0,17	neutral	2,24	neutral	-1,31	deleterious	-2,97	medium_impact	3,38	neutral	0,68	neutral	0,34	deleterious	1,98	16,09	0,05	0,35	disease	0,85	disease	0,82	disease	0,56	disease	0,76	5	neutral	0,8	neutral	0,39	neutral	-3	deleterious	0,71	medium_impact	-0,55	medium_impact	-0,18	high_impact	2,22	0,35	0,8	15,03	13,44	N	0,32	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11996	11996	A	G	MI.18917	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1237	413	T	A	Aca/Gca	-9,41	0	0	benign	0,11	neutral	0,47	neutral	2,3	neutral	0,31	neutral	-1,78	low_impact	1,79	neutral	0,76	neutral	0,81	deleterious	0,57	7,92	0,22	0,45	disease	0,55	neutral	0,35	neutral	0,24	disease	0,61	2	neutral	0,46	deleterious	0,68	neutral	-6	neutral	0,26	medium_impact	0,14	medium_impact	0,17	medium_impact	0,65	0,37	0,8	15,03	13,44	N	0,38	N	0,77	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11996	11996	A	T	MI.18918	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1237	413	T	S	Aca/Tca	-9,41	0	0	benign	0,01	neutral	0,54	neutral	2,33	neutral	-0,01	neutral	-0,98	neutral_impact	0,24	neutral	0,72	neutral	0,98	deleterious	0,3	5,71	0,31	0,45	disease	0,61	neutral	0,26	neutral	0,18	disease	0,56	1	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,31	medium_impact	1,16	medium_impact	0,24	medium_impact	-0,89	0,63	0,8	15,03	13,44	N	0,43	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11997	11997	C	A	MI.18919	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1238	413	T	K	aCa/aAa	1,87	0	0	benign	0,16	neutral	0,27	neutral	2,32	neutral	0,09	neutral	-2,45	medium_impact	3,03	neutral	0,71	neutral	0,44	deleterious	2,68	20,7	0,09	0,4	disease	0,81	disease	0,69	disease	0,54	disease	0,65	3	neutral	0,68	deleterious	0,56	neutral	-3	deleterious	0,49	medium_impact	-0,04	medium_impact	-0,04	medium_impact	1,87	0,36	0,8	15,03	13,44	N	0,36	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5910	5910	G	T	MI.1892	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	7	3	A	S	Gcc/Tcc	-0,57	0	0	benign	0,04	neutral	0,14	neutral	2,96	neutral	-0,68	neutral	-0,03	neutral_impact	0,34	neutral	0,7	neutral	0,8	deleterious	0,31	5,77	0,45	0,55	neutral	0,26	neutral	0,03	neutral	0,06	neutral	0,1	8	neutral	0,85	deleterious	0,55	neutral	-6	neutral	0,1	medium_impact	0,54	medium_impact	-0,25	medium_impact	-0,79	0,67	0,9	11,5	19,25	P	0,66	P	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11997	11997	C	T	MI.18920	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1238	413	T	M	aCa/aTa	1,87	0	0	benign	0,03	neutral	0,39	neutral	2,28	neutral	0,18	neutral	-0,56	neutral_impact	0,74	neutral	0,75	neutral	0,98	neutral	-0,53	0,19	0,14	0,4	neutral	0,43	neutral	0,1	neutral	0,18	neutral	0,31	4	neutral	0,59	deleterious	0,68	neutral	-6	neutral	0,14	medium_impact	0,7	medium_impact	0,09	medium_impact	-0,39	0,61	0,8	15,03	13,44	P	0,56	P	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11999	11999	A	G	MI.18921	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1240	414	T	A	Aca/Gca	-1,12	0	0	benign	0,22	deleterious	0,04	neutral	2,11	neutral	-1,79	deleterious	-3,77	medium_impact	3,12	neutral	0,73	neutral	0,66	deleterious	3,58	23,2	0,27	0,45	neutral	0,46	disease	0,58	disease	0,54	disease	0,53	1	neutral	0,95	neutral	0,41	deleterious	1	deleterious	0,72	medium_impact	-0,2	medium_impact	-0,57	medium_impact	1,96	0,44	0,8	23,75	20,1	N	0,45	N	0,81	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11999	11999	A	C	MI.18922	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1240	414	T	P	Aca/Cca	-1,12	0	0	possibly_damaging	0,87	deleterious	0,02	neutral	2,02	deleterious	-5,7	deleterious	-4,86	high_impact	4,01	neutral	0,68	neutral	0,39	deleterious	3,59	23,2	0,03	0,35	neutral	0,5	disease	0,84	disease	0,76	disease	0,77	5	deleterious	0,99	neutral	0,08	deleterious	5	deleterious	0,79	low_impact	-1,49	medium_impact	-0,75	high_impact	2,84	0,33	0,8	23,75	20,1	N	0,46	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	11999	11999	A	T	MI.18923	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1240	414	T	S	Aca/Tca	-1,12	0	0	possibly_damaging	0,47	neutral	0,5	neutral	2,08	neutral	-1,6	deleterious	-2,75	medium_impact	2,04	neutral	0,68	neutral	0,84	deleterious	2,22	17,67	0,32	0,5	disease	0,7	neutral	0,3	neutral	0,3	disease	0,59	2	neutral	0,48	deleterious	0,52	NA	0	deleterious	0,73	medium_impact	-0,67	medium_impact	0,2	medium_impact	0,89	0,62	0,8	23,75	20,1	N	0,37	N	0,39	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12000	12000	C	T	MI.18924	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1241	414	T	M	aCa/aTa	4,4	0,96	0	benign	0,07	neutral	0,07	neutral	2,09	neutral	-0,24	deleterious	-4,73	medium_impact	2,56	neutral	0,73	neutral	0,56	deleterious	4,03	23,6	0,09	0,35	disease	0,77	disease	0,74	disease	0,65	disease	0,64	3	neutral	0,92	deleterious	0,5	neutral	-3	deleterious	0,78	medium_impact	0,34	medium_impact	-0,43	medium_impact	1,41	0,52	0,8	23,75	20,1	P	0,48	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12000	12000	C	A	MI.18925	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1241	414	T	K	aCa/aAa	4,4	0,96	0	possibly_damaging	0,6	deleterious	0,01	neutral	2,03	deleterious	-4,65	deleterious	-4,74	high_impact	4,01	neutral	0,71	neutral	0,42	deleterious	4,57	24,4	0,05	0,35	disease	0,85	disease	0,82	disease	0,75	disease	0,81	6	deleterious	0,99	neutral	0,21	deleterious	5	deleterious	0,84	medium_impact	-0,88	medium_impact	-0,92	high_impact	2,84	0,28	0,8	23,75	20,1	P	0,58	P	0,93	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12002	12002	C	A	MI.18926	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1243	415	Q	K	Caa/Aaa	-5,96	0	0	probably_damaging	0,99	deleterious	0,02	neutral	2,22	neutral	-2,7	deleterious	-3,66	high_impact	4,21	neutral	0,71	damaging	0,12	deleterious	4,05	23,7	0,18	0,45	neutral	0,4	disease	0,8	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-2,59	medium_impact	-0,75	high_impact	3,04	0,26	0,8	46,62	9,42	N	0,36	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12002	12002	C	G	MI.18927	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1243	415	Q	E	Caa/Gaa	-5,96	0	0	probably_damaging	0,98	deleterious	0,02	neutral	2,22	neutral	-2,75	deleterious	-2,75	high_impact	4,21	neutral	0,72	damaging	0,14	deleterious	3,1	22,5	0,3	0,45	disease	0,81	disease	0,75	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,77	low_impact	-2,31	medium_impact	-0,75	high_impact	3,04	0,33	0,8	46,62	9,42	N	0,39	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12003	12003	A	G	MI.18928	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1244	415	Q	R	cAa/cGa	7,17	1	0	probably_damaging	0,99	neutral	0,08	neutral	2,23	neutral	-1,07	deleterious	-3,66	high_impact	4,21	neutral	0,7	damaging	0,12	deleterious	3,44	23	0,18	0,45	disease	0,78	disease	0,84	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,83	low_impact	-2,59	medium_impact	-0,39	high_impact	3,04	0,12	0,8	46,62	9,42	P	0,69	P	0,86	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12003	12003	A	T	MI.18929	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1244	415	Q	L	cAa/cTa	7,17	1	0	probably_damaging	0,99	neutral	0,07	neutral	2,33	neutral	-2,52	deleterious	-6,41	high_impact	3,86	neutral	0,63	damaging	0,13	deleterious	3,77	23,4	0,1	0,4	neutral	0,42	disease	0,87	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,77	low_impact	-2,59	medium_impact	-0,43	high_impact	2,69	0,05	0,8	46,62	9,42	P	0,61	P	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5910	5910	G	A	MI.1893	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	7	3	A	T	Gcc/Acc	-0,57	0	0	benign	0,02	neutral	0,09	neutral	2,97	neutral	-0,4	neutral	0,02	low_impact	1,25	neutral	0,8	neutral	0,94	neutral	1,08	11,09	0,4	0,55	neutral	0,22	neutral	0,05	neutral	0,06	neutral	0,1	8	neutral	0,91	deleterious	0,54	neutral	-6	neutral	0,07	medium_impact	0,83	medium_impact	-0,37	medium_impact	0,06	0,7	0,9	11,5	19,25	P	0,63	P	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12003	12003	A	C	MI.18930	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1244	415	Q	P	cAa/cCa	7,17	1	0	probably_damaging	1	deleterious	0,01	neutral	2,21	deleterious	-4,42	deleterious	-5,5	high_impact	4,21	neutral	0,68	damaging	0,14	deleterious	3,35	22,9	0,03	0,35	disease	0,66	disease	0,83	disease	0,79	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,54	medium_impact	-0,92	high_impact	3,04	0,22	0,8	46,62	9,42	P	0,62	P	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12004	12004	A	C	MI.18931	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1245	415	Q	H	caA/caC	8,55	1	0	probably_damaging	1	deleterious	0,04	neutral	2,21	deleterious	-4,21	deleterious	-4,58	medium_impact	3,11	neutral	0,67	damaging	0,12	deleterious	3,66	23,2	0,18	0,45	disease	0,83	disease	0,78	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,85	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,95	0,44	0,8	46,62	9,42	P	0,56	P	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12004	12004	A	T	MI.18932	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1245	415	Q	H	caA/caT	8,55	1	0	probably_damaging	1	deleterious	0,04	neutral	2,21	deleterious	-4,21	deleterious	-4,58	medium_impact	3,11	neutral	0,67	damaging	0,12	deleterious	3,75	23,3	0,18	0,45	disease	0,83	disease	0,78	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,85	low_impact	-3,54	medium_impact	-0,57	medium_impact	1,95	0,44	0,8	46,62	9,42	P	0,56	P	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12005	12005	T	C	MI.18933	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1246	416	W	R	Tgg/Cgg	2,56	1	0	benign	0	neutral	0,77	neutral	2,33	neutral	-1,49	neutral	6,47	neutral_impact	-2,27	neutral	0,76	neutral	0,9	neutral	-0,93	0,02	0,06	0,35	disease	0,59	neutral	0,1	neutral	0,28	neutral	0,29	4	neutral	0,23	deleterious	0,89	neutral	-6	neutral	0,15	high_impact	2,1	medium_impact	0,5	low_impact	-3,37	0,09	0,8	42,7	8,57	N	0,4	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	COSM1497298	.	.	.	.	.	.	.	.
chrM	12005	12005	T	G	MI.18934	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1246	416	W	G	Tgg/Ggg	2,56	1	0	benign	0,04	deleterious	0,04	neutral	2,29	neutral	-1,49	neutral	0,49	low_impact	0,98	neutral	0,74	neutral	0,53	deleterious	2,11	16,91	0,08	0,35	disease	0,86	neutral	0,45	disease	0,68	disease	0,69	4	neutral	0,96	deleterious	0,5	neutral	-2	neutral	0,29	medium_impact	0,58	medium_impact	-0,57	medium_impact	-0,16	0,1	0,8	42,7	8,57	N	0,46	N	0,51	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12006	12006	G	C	MI.18935	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1247	416	W	S	tGg/tCg	2,33	1	0	benign	0,03	neutral	0,12	neutral	2,33	neutral	-0,7	neutral	1,37	low_impact	1,52	neutral	0,75	neutral	0,6	deleterious	2,2	17,53	0,09	0,35	disease	0,72	neutral	0,45	disease	0,57	disease	0,67	3	neutral	0,87	deleterious	0,55	neutral	-6	neutral	0,27	medium_impact	0,7	medium_impact	-0,28	medium_impact	0,38	0,09	0,8	42,7	8,57	P	0,51	P	0,38	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12006	12006	G	T	MI.18936	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1247	416	W	L	tGg/tTg	2,33	1	0	benign	0,02	neutral	0,1	neutral	2,35	neutral	0,49	neutral	0,49	low_impact	0,83	neutral	0,74	neutral	0,56	deleterious	2,43	19,02	0,1	0,4	disease	0,59	neutral	0,39	disease	0,6	disease	0,64	3	neutral	0,9	deleterious	0,54	neutral	-6	neutral	0,21	medium_impact	0,87	medium_impact	-0,33	medium_impact	-0,31	0,04	0,8	42,7	8,57	N	0,5	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12007	12007	G	C	MI.18937	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1248	416	W	C	tgG/tgC	1,64	0,97	0,03	possibly_damaging	0,54	deleterious	0,02	neutral	2,26	neutral	-2,69	neutral	-0,26	low_impact	1,52	neutral	0,81	neutral	0,43	deleterious	2,49	19,39	0,07	0,35	disease	0,74	disease	0,63	disease	0,52	disease	0,59	2	neutral	0,98	neutral	0,24	deleterious	1	deleterious	0,57	medium_impact	-0,78	medium_impact	-0,75	medium_impact	0,38	0,07	0,8	42,7	8,57	N	0,4	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12007	12007	G	T	MI.18938	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1248	416	W	C	tgG/tgT	1,64	0,97	0,03	possibly_damaging	0,54	deleterious	0,02	neutral	2,26	neutral	-2,69	neutral	-0,26	low_impact	1,52	neutral	0,81	neutral	0,43	deleterious	2,6	20,2	0,07	0,35	disease	0,74	disease	0,63	disease	0,52	disease	0,59	2	neutral	0,98	neutral	0,24	deleterious	1	deleterious	0,57	medium_impact	-0,78	medium_impact	-0,75	medium_impact	0,38	0,07	0,8	42,7	8,57	N	0,41	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12008	12008	G	A	MI.18939	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1249	417	G	S	Ggc/Agc	-2,04	0	0	possibly_damaging	0,84	neutral	0,06	neutral	1,84	neutral	-2,9	deleterious	-5,26	medium_impact	2,6	neutral	0,7	neutral	0,47	deleterious	4,28	24	0,11	0,4	disease	0,72	disease	0,77	neutral	0,26	neutral	0,47	1	neutral	0,97	neutral	0,11	NA	0	deleterious	0,83	low_impact	-1,39	medium_impact	-0,47	medium_impact	1,45	0,48	0,8	47,71	9,31	N	0,45	N	0,96	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5911	5911	C	A	MI.1894	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	8	3	A	D	gCc/gAc	-0,11	0	0	benign	0,16	deleterious	0	neutral	2,9	neutral	-2,3	neutral	-0,21	low_impact	1,25	damaging	0,6	neutral	0,58	deleterious	2,59	20,1	0,29	0,55	disease	0,53	neutral	0,22	neutral	0,22	neutral	0,24	5	deleterious	1	neutral	0,42	neutral	-2	neutral	0,2	medium_impact	-0,08	low_impact	-1,48	medium_impact	0,06	0,48	0,9	11,5	19,25	P	0,52	P	0,27	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12008	12008	G	T	MI.18940	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1249	417	G	C	Ggc/Tgc	-2,04	0	0	probably_damaging	1	deleterious	0	neutral	1,76	deleterious	-5,98	deleterious	-8,04	high_impact	4,05	neutral	0,7	neutral	0,3	deleterious	4,35	24,1	0,06	0,35	disease	0,87	disease	0,91	disease	0,62	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,54	low_impact	-1,48	high_impact	2,88	0,11	0,8	47,71	9,31	N	0,35	N	0,98	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12008	12008	G	C	MI.18941	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1249	417	G	R	Ggc/Cgc	-2,04	0	0	probably_damaging	0,92	deleterious	0,01	neutral	1,81	deleterious	-3,42	deleterious	-7,02	high_impact	3,7	neutral	0,72	neutral	0,31	deleterious	4,11	23,7	0,06	0,35	disease	0,94	disease	0,9	disease	0,7	disease	0,83	7	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,91	low_impact	-1,71	medium_impact	-0,92	high_impact	2,53	0,44	0,8	47,71	9,31	N	0,33	N	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12009	12009	G	A	MI.18942	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1250	417	G	D	gGc/gAc	6,01	1	0	possibly_damaging	0,89	deleterious	0	neutral	1,8	deleterious	-3,58	deleterious	-6,15	high_impact	4,05	neutral	0,74	neutral	0,34	deleterious	3,92	23,5	0,05	0,35	disease	0,97	disease	0,87	disease	0,68	disease	0,83	7	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,87	low_impact	-1,57	low_impact	-1,48	high_impact	2,88	0,11	0,8	47,71	9,31	P	0,64	P	0,99	polymorphism	1	0,34	.	.	.	.	.	.	COSM488730	.	.	.	.	.	.	.	.
chrM	12009	12009	G	C	MI.18943	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1250	417	G	A	gGc/gCc	6,01	1	0	possibly_damaging	0,75	deleterious	0	neutral	1,85	neutral	-2,68	deleterious	-5,36	medium_impact	3,25	neutral	0,71	neutral	0,47	deleterious	3,26	22,8	0,13	0,4	disease	0,54	disease	0,7	disease	0,58	disease	0,64	3	deleterious	1	neutral	0,13	deleterious	4	deleterious	0,79	low_impact	-1,17	low_impact	-1,48	high_impact	2,09	0,19	0,8	47,71	9,31	P	0,61	P	0,76	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12009	12009	G	T	MI.18944	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1250	417	G	V	gGc/gTc	6,01	1	0	probably_damaging	0,96	deleterious	0	neutral	1,82	deleterious	-3,3	deleterious	-8,04	high_impact	4,05	neutral	0,71	neutral	0,38	deleterious	3,95	23,6	0,05	0,35	disease	0,8	disease	0,86	disease	0,61	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-2,01	low_impact	-1,48	high_impact	2,88	0,07	0,8	47,71	9,31	P	0,62	P	0,98	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12011	12011	T	C	MI.18945	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1252	418	S	P	Tca/Cca	-20	0	0	benign	0	neutral	0,52	neutral	2,27	neutral	1,09	neutral	0,85	neutral_impact	-1,29	neutral	0,76	neutral	0,89	neutral	-0,56	0,16	0,2	0,45	disease	0,84	neutral	0,32	neutral	0,07	disease	0,66	3	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,24	high_impact	2,1	medium_impact	0,22	low_impact	-2,4	0,15	0,8	26,58	34,23	N	0,4	N	0,12	polymorphism	1	0	rs386829144	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12011	12011	T	A	MI.18946	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1252	418	S	T	Tca/Aca	-20	0	0	benign	0	neutral	0,43	neutral	2,28	neutral	1,33	neutral	-0,35	neutral_impact	-1,27	neutral	0,78	neutral	0,87	deleterious	0,8	9,49	0,6	0,65	disease	0,55	neutral	0,26	neutral	0,08	disease	0,55	1	neutral	0,57	deleterious	0,72	neutral	-6	neutral	0,15	high_impact	2,1	medium_impact	0,13	low_impact	-2,38	0,37	0,8	26,58	34,23	N	0,46	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12011	12011	T	G	MI.18947	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1252	418	S	A	Tca/Gca	-20	0	0	benign	0	neutral	0,47	neutral	2,29	neutral	0,84	neutral	-0,74	neutral_impact	-0,38	neutral	0,8	neutral	0,9	deleterious	0,86	9,8	0,64	0,7	disease	0,53	neutral	0,26	neutral	0,16	neutral	0,41	2	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,15	high_impact	2,1	medium_impact	0,17	low_impact	-1,5	0,24	0,8	26,58	34,23	N	0,45	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12012	12012	C	G	MI.18948	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1253	418	S	W	tCa/tGa	0,26	0	0	benign	0,26	deleterious	0,03	neutral	2,19	deleterious	-4,96	deleterious	-2,73	low_impact	1,45	neutral	0,77	neutral	0,45	deleterious	2,58	19,96	0,11	0,4	disease	0,92	disease	0,75	neutral	0,43	disease	0,79	6	neutral	0,97	neutral	0,39	neutral	-2	deleterious	0,53	medium_impact	-0,29	medium_impact	-0,64	medium_impact	0,31	0,12	0,8	26,58	34,23	N	0,32	N	0,56	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12012	12012	C	T	MI.18949	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1253	418	S	L	tCa/tTa	0,26	0	0	benign	0	neutral	0,26	neutral	2,22	neutral	-1,86	neutral	-1,57	neutral_impact	0,47	neutral	0,8	neutral	0,78	neutral	1,75	14,71	0,25	0,45	neutral	0,35	disease	0,54	neutral	0,22	neutral	0,44	1	neutral	0,74	deleterious	0,63	neutral	-6	neutral	0,15	high_impact	2,1	medium_impact	-0,05	medium_impact	-0,66	0,43	0,8	26,58	34,23	N	0,39	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5911	5911	C	T	MI.1895	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	8	3	A	V	gCc/gTc	-0,11	0	0	benign	0	neutral	0,11	neutral	3,05	neutral	0,55	neutral	0,15	neutral_impact	0,2	neutral	0,89	neutral	0,98	neutral	0,99	10,61	0,34	0,55	neutral	0,25	neutral	0,05	neutral	0,07	neutral	0,11	8	neutral	0,89	deleterious	0,56	neutral	-6	neutral	0,07	high_impact	2,07	medium_impact	-0,31	medium_impact	-0,91	0,8	0,9	11,5	19,25	P	0,68	P	0	polymorphism	1	0	rs879227822	.	.	.	.	.	.	.	.	C5911T	Prostate Cancer	+	-	Reported	1
chrM	12014	12014	C	A	MI.18950	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1255	419	L	I	Ctc/Atc	-1,81	0	0	benign	0,31	neutral	0,54	neutral	2,13	neutral	-2,67	neutral	-0,59	medium_impact	2,08	neutral	0,77	neutral	0,82	neutral	1,02	10,79	0,48	0,55	neutral	0,44	neutral	0,3	neutral	0,17	neutral	0,47	1	neutral	0,37	deleterious	0,62	neutral	-3	neutral	0,31	medium_impact	-0,39	medium_impact	0,24	medium_impact	0,93	0,38	0,8	29,63	25,35	N	0,4	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12014	12014	C	G	MI.18951	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1255	419	L	V	Ctc/Gtc	-1,81	0	0	benign	0,31	neutral	0,53	neutral	2,17	deleterious	-3,17	neutral	-0,7	medium_impact	2,62	neutral	0,76	neutral	0,77	deleterious	0,27	5,45	0,46	0,55	neutral	0,45	neutral	0,3	neutral	0,2	neutral	0,47	1	neutral	0,38	deleterious	0,61	neutral	-3	neutral	0,2	medium_impact	-0,39	medium_impact	0,23	medium_impact	1,47	0,33	0,8	29,63	25,35	N	0,39	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12014	12014	C	T	MI.18952	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1255	419	L	F	Ctc/Ttc	-1,81	0	0	benign	0,03	neutral	0,78	neutral	2,1	neutral	-2,1	neutral	-1,15	medium_impact	2,31	neutral	0,83	neutral	0,92	neutral	0,98	10,54	0,45	0,55	disease	0,53	neutral	0,35	neutral	0,2	neutral	0,42	2	neutral	0,16	deleterious	0,88	neutral	-3	deleterious	0,52	medium_impact	0,7	medium_impact	0,51	medium_impact	1,16	0,4	0,8	29,63	25,35	N	0,34	N	0,2	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12015	12015	T	C	MI.18953	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1256	419	L	P	cTc/cCc	-6,19	0	0	benign	0,01	neutral	0,33	neutral	2,08	neutral	-0,73	neutral	-2,12	low_impact	1,21	neutral	0,81	neutral	0,94	deleterious	0,79	9,43	0,14	0,4	disease	0,94	disease	0,65	neutral	0,21	disease	0,7	4	neutral	0,66	deleterious	0,66	neutral	-6	neutral	0,3	medium_impact	1,16	medium_impact	0,03	medium_impact	0,07	0,19	0,8	29,63	25,35	N	0,31	N	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12015	12015	T	G	MI.18954	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1256	419	L	R	cTc/cGc	-6,19	0	0	possibly_damaging	0,82	neutral	0,29	neutral	2,06	neutral	-0,92	deleterious	-2,67	high_impact	3,66	neutral	0,7	neutral	0,49	neutral	1,63	14,04	0,11	0,4	disease	0,91	disease	0,78	neutral	0,5	disease	0,72	4	neutral	0,86	neutral	0,24	deleterious	1	deleterious	0,64	low_impact	-1,34	medium_impact	-0,02	high_impact	2,5	0,16	0,8	29,63	25,35	N	0,39	N	0,57	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12015	12015	T	A	MI.18955	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1256	419	L	H	cTc/cAc	-6,19	0	0	probably_damaging	0,91	neutral	0,52	neutral	2,03	deleterious	-3,3	deleterious	-2,7	medium_impact	2,77	neutral	0,82	neutral	0,84	deleterious	2,84	21,6	0,17	0,45	disease	0,94	disease	0,63	neutral	0,27	disease	0,69	4	neutral	0,9	neutral	0,31	deleterious	1	deleterious	0,69	low_impact	-1,66	medium_impact	0,22	medium_impact	1,61	0,12	0,8	29,63	25,35	N	0,3	N	0,52	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12017	12017	A	C	MI.18956	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1258	420	T	P	Acc/Ccc	-7,34	0	0	possibly_damaging	0,6	neutral	0,38	neutral	2,23	neutral	1,42	neutral	-0,34	neutral_impact	0,74	neutral	0,64	neutral	0,9	neutral	-0,85	0,03	0,15	0,4	disease	0,88	neutral	0,07	neutral	0,13	neutral	0,4	2	neutral	0,65	neutral	0,39	neutral	-3	deleterious	0,51	medium_impact	-0,88	medium_impact	0,08	medium_impact	-0,39	0,33	0,8	15,9	10,5	N	0,49	N	0,56	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12017	12017	A	G	MI.18957	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1258	420	T	A	Acc/Gcc	-7,34	0	0	benign	0,01	neutral	0,46	neutral	2,28	neutral	0,52	neutral	-2,14	medium_impact	2,22	neutral	0,77	neutral	0,7	neutral	1,65	14,12	0,49	0,55	disease	0,82	neutral	0,27	disease	0,55	disease	0,6	2	neutral	0,53	deleterious	0,73	neutral	-3	neutral	0,28	medium_impact	1,16	medium_impact	0,16	medium_impact	1,07	0,28	0,8	15,9	10,5	N	0,3	N	0,84	polymorphism	1	0,03	rs879136236	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12017	12017	A	T	MI.18958	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1258	420	T	S	Acc/Tcc	-7,34	0	0	benign	0,02	neutral	0,47	neutral	2,3	neutral	0,38	neutral	-1,28	low_impact	1,4	neutral	0,73	neutral	0,96	deleterious	0,22	4,85	0,71	0,75	disease	0,51	neutral	0,23	neutral	0,21	neutral	0,35	3	neutral	0,51	deleterious	0,73	neutral	-6	neutral	0,17	medium_impact	0,87	medium_impact	0,17	medium_impact	0,26	0,55	0,8	15,9	10,5	N	0,44	N	0,36	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12018	12018	C	G	MI.18959	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1259	420	T	S	aCc/aGc	0,26	0	0	benign	0,02	neutral	0,47	neutral	2,3	neutral	0,38	neutral	-1,28	low_impact	1,4	neutral	0,73	neutral	0,96	deleterious	0,46	7,11	0,71	0,75	disease	0,51	neutral	0,23	neutral	0,21	neutral	0,35	3	neutral	0,51	deleterious	0,73	neutral	-6	neutral	0,17	medium_impact	0,87	medium_impact	0,17	medium_impact	0,26	0,55	0,8	15,9	10,5	N	0,44	N	0,36	polymorphism	1	0,02	rs1057516068	Uncertain significance|Uncertain significance|Uncertain significance|Uncertain significance|Uncertain significance|Uncertain significance|Uncertain significance|Uncertain significance|Uncertain significance|Uncertain significance|Uncertain significance|Uncertain significance|Uncertain significance|Uncertain significance	Congenital_cardiomyopathy|Developmental_delay|Hearing_impairment|Microcephaly|Developmental_delay|Hearing_impairment|Macrocephaly|Calcification_of_extrapyramidal_basal_ganglia|Dementia|Developmental_delay|Encephalopathy|Muscular_hypotonia|Seizure_Disorders|Leigh_syndrome	RCV000408926.1|RCV000408926.1|RCV000408926.1|RCV000408926.1|RCV000408940.1|RCV000408940.1|RCV000408940.1|RCV000408949.1|RCV000408949.1|RCV000408949.1|RCV000408949.1|RCV000408949.1|RCV000408949.1|RCV000408952.1	MedGen|MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen:OMIM|MedGen|Human_Phenotype_Ontology:MedGen|MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|MedGen|MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	5911	5911	C	G	MI.1896	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	8	3	A	G	gCc/gGc	-0,11	0	0	benign	0,05	deleterious	0	neutral	2,91	neutral	-1,75	neutral	-0,23	low_impact	1,25	neutral	0,67	neutral	0,64	deleterious	1,98	16,1	0,32	0,55	neutral	0,24	neutral	0,07	neutral	0,13	neutral	0,1	8	deleterious	1	deleterious	0,48	neutral	-2	neutral	0,09	medium_impact	0,45	low_impact	-1,48	medium_impact	0,06	0,73	0,9	11,5	19,25	P	0,64	P	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12018	12018	C	T	MI.18960	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1259	420	T	I	aCc/aTc	0,26	0	0	benign	0,32	neutral	0,37	neutral	2,22	deleterious	-3,17	deleterious	-3,59	medium_impact	2,68	neutral	0,72	neutral	0,53	deleterious	2,4	18,84	0,31	0,45	disease	0,95	neutral	0,5	neutral	0,45	disease	0,81	6	neutral	0,56	deleterious	0,53	neutral	-3	deleterious	0,56	medium_impact	-0,41	medium_impact	0,07	medium_impact	1,53	0,36	0,8	15,9	10,5	N	0,34	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12018	12018	C	A	MI.18961	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1259	420	T	N	aCc/aAc	0,26	0	0	benign	0,32	neutral	0,3	neutral	2,29	neutral	-0,2	neutral	-2,21	medium_impact	2,56	neutral	0,76	neutral	0,71	deleterious	1,88	15,48	0,64	0,7	disease	0,84	disease	0,54	neutral	0,26	disease	0,59	2	neutral	0,64	deleterious	0,49	neutral	-3	neutral	0,36	medium_impact	-0,41	medium_impact	0	medium_impact	1,41	0,55	0,8	15,9	10,5	N	0,37	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12020	12020	C	A	MI.18962	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1261	421	H	N	Cac/Aac	-14,47	0	0	benign	0,13	neutral	0,51	neutral	2,33	neutral	-0,01	neutral	-1,32	low_impact	1,09	neutral	0,7	neutral	0,95	deleterious	1,98	16,1	0,57	0,65	disease	0,64	neutral	0,21	neutral	0,3	neutral	0,49	0	neutral	0,4	deleterious	0,69	neutral	-6	deleterious	0,64	medium_impact	0,06	medium_impact	0,21	medium_impact	-0,05	0,31	0,8	22,44	19,28	N	0,41	N	0,52	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12020	12020	C	G	MI.18963	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1261	421	H	D	Cac/Gac	-14,47	0	0	benign	0,13	neutral	0,24	neutral	2,31	neutral	0,86	deleterious	-2,83	medium_impact	2,08	neutral	0,79	neutral	0,88	deleterious	2,61	20,3	0,32	0,5	disease	0,78	neutral	0,4	neutral	0,48	disease	0,64	3	neutral	0,72	deleterious	0,56	neutral	-3	deleterious	0,71	medium_impact	0,06	medium_impact	-0,08	medium_impact	0,93	0,38	0,8	22,44	19,28	N	0,37	N	0,83	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12020	12020	C	T	MI.18964	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1261	421	H	Y	Cac/Tac	-14,47	0	0	benign	0	neutral	1	neutral	2,28	neutral	-0,79	neutral	-0,69	low_impact	0,84	neutral	0,83	neutral	0,95	neutral	1,4	12,79	0,29	0,45	disease	0,6	neutral	0,32	neutral	0,33	disease	0,59	2	neutral	0	deleterious	1	neutral	-6	deleterious	0,66	high_impact	2,1	high_impact	1,88	medium_impact	-0,3	0,2	0,8	22,44	19,28	N	0,3	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12021	12021	A	G	MI.18965	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1262	421	H	R	cAc/cGc	-5,96	0	0	benign	0,18	neutral	0,37	neutral	2,31	neutral	-0,75	deleterious	-2,62	medium_impact	2,78	neutral	0,78	neutral	0,5	deleterious	2,23	17,73	0,36	0,5	disease	0,67	neutral	0,38	neutral	0,39	disease	0,62	2	neutral	0,56	deleterious	0,6	neutral	-3	deleterious	0,7	medium_impact	-0,1	medium_impact	0,07	medium_impact	1,62	0,18	0,8	22,44	19,28	N	0,33	N	0,75	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12021	12021	A	C	MI.18966	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1262	421	H	P	cAc/cCc	-5,96	0	0	benign	0	neutral	0,25	neutral	2,3	neutral	1,89	deleterious	-3,29	low_impact	0,95	neutral	0,77	neutral	0,79	deleterious	2,32	18,31	0,17	0,45	disease	0,76	disease	0,57	neutral	0,34	disease	0,51	0	neutral	0,75	deleterious	0,63	neutral	-6	deleterious	0,77	high_impact	2,1	medium_impact	-0,07	medium_impact	-0,19	0,27	0,8	22,44	19,28	N	0,33	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12021	12021	A	T	MI.18967	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1262	421	H	L	cAc/cTc	-5,96	0	0	benign	0,08	neutral	0,74	neutral	2,3	neutral	-0,22	deleterious	-3,75	low_impact	0,96	neutral	0,76	neutral	0,75	deleterious	2,92	21,9	0,29	0,45	disease	0,52	neutral	0,36	neutral	0,43	neutral	0,36	3	neutral	0,16	deleterious	0,83	neutral	-6	deleterious	0,65	medium_impact	0,28	medium_impact	0,46	medium_impact	-0,18	0,12	0,8	22,44	19,28	N	0,26	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12022	12022	C	A	MI.18968	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1263	421	H	Q	caC/caA	-0,66	0	0	benign	0,33	neutral	0,37	neutral	2,32	neutral	0,26	neutral	-2,1	low_impact	1,31	neutral	0,71	neutral	0,88	deleterious	2,12	17	0,45	0,55	disease	0,69	neutral	0,22	neutral	0,27	neutral	0,5	0	neutral	0,56	deleterious	0,52	neutral	-6	deleterious	0,68	medium_impact	-0,43	medium_impact	0,07	medium_impact	0,17	0,4	0,8	22,44	19,28	N	0,38	N	0,7	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12022	12022	C	G	MI.18969	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1263	421	H	Q	caC/caG	-0,66	0	0	benign	0,33	neutral	0,37	neutral	2,32	neutral	0,26	neutral	-2,1	low_impact	1,31	neutral	0,71	neutral	0,88	neutral	1,79	14,91	0,45	0,55	disease	0,69	neutral	0,22	neutral	0,27	neutral	0,5	0	neutral	0,56	deleterious	0,52	neutral	-6	deleterious	0,68	medium_impact	-0,43	medium_impact	0,07	medium_impact	0,17	0,4	0,8	22,44	19,28	N	0,38	N	0,7	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5913	5913	G	C	MI.1897	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	10	4	D	H	Gac/Cac	-5,89	0	0	benign	0,04	neutral	0,06	neutral	2,99	neutral	-1,17	neutral	0,02	neutral_impact	-1,15	neutral	0,72	neutral	0,64	neutral	1,78	14,89	0,46	0,55	neutral	0,36	neutral	0,11	neutral	0,28	neutral	0,28	4	neutral	0,94	deleterious	0,51	neutral	-6	neutral	0,14	medium_impact	0,54	medium_impact	-0,47	low_impact	-2,16	0,52	0,9	13,26	25,03	N	0,5	N	0,19	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12023	12023	C	A	MI.18970	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1264	422	H	N	Cac/Aac	-1,81	0	0	possibly_damaging	0,52	neutral	0,4	neutral	2,28	neutral	0,13	deleterious	-5,24	low_impact	1,27	neutral	0,75	damaging	0,27	deleterious	4,06	23,7	0,55	0,6	disease	0,81	disease	0,62	neutral	0,45	disease	0,58	1	neutral	0,59	neutral	0,44	neutral	-3	deleterious	0,76	medium_impact	-0,75	medium_impact	0,1	medium_impact	0,13	0,34	0,8	15,69	15,43	N	0,25	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12023	12023	C	G	MI.18971	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1264	422	H	D	Cac/Gac	-1,81	0	0	possibly_damaging	0,73	neutral	0,21	neutral	2,24	neutral	-0,36	deleterious	-7,13	low_impact	1,88	neutral	0,69	damaging	0,14	deleterious	3,9	23,5	0,27	0,45	disease	0,88	disease	0,71	disease	0,67	disease	0,73	5	neutral	0,84	neutral	0,24	neutral	-3	deleterious	0,79	low_impact	-1,12	medium_impact	-0,12	medium_impact	0,73	0,29	0,8	15,69	15,43	N	0,27	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12023	12023	C	T	MI.18972	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1264	422	H	Y	Cac/Tac	-1,81	0	0	possibly_damaging	0,88	neutral	0,93	neutral	2,21	neutral	-2,56	deleterious	-4,89	medium_impact	2,14	neutral	0,76	neutral	0,32	deleterious	3,71	23,3	0,31	0,45	disease	0,73	disease	0,73	neutral	0,47	disease	0,57	1	neutral	0,87	deleterious	0,53	NA	0	deleterious	0,78	low_impact	-1,53	medium_impact	0,83	medium_impact	0,99	0,35	0,8	15,69	15,43	N	0,2	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12024	12024	A	C	MI.18973	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1265	422	H	P	cAc/cCc	2,79	0,94	0	probably_damaging	0,92	neutral	0,15	neutral	2,22	deleterious	-3,27	deleterious	-8,11	medium_impact	2,78	neutral	0,65	damaging	0,15	deleterious	3,29	22,8	0,17	0,45	disease	0,83	disease	0,85	disease	0,69	disease	0,73	5	neutral	0,96	neutral	0,12	deleterious	1	deleterious	0,86	low_impact	-1,71	medium_impact	-0,22	medium_impact	1,62	0,29	0,8	15,69	15,43	N	0,43	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12024	12024	A	G	MI.18974	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1265	422	H	R	cAc/cGc	2,79	0,94	0	possibly_damaging	0,78	neutral	0,24	neutral	2,25	neutral	0,72	deleterious	-6,42	high_impact	3,58	neutral	0,66	damaging	0,12	deleterious	3,07	22,5	0,36	0,5	disease	0,78	disease	0,76	disease	0,67	disease	0,68	4	neutral	0,85	neutral	0,23	deleterious	1	deleterious	0,8	low_impact	-1,23	medium_impact	-0,08	high_impact	2,42	0,18	0,8	15,69	15,43	N	0,43	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12024	12024	A	T	MI.18975	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1265	422	H	L	cAc/cTc	2,79	0,94	0	possibly_damaging	0,78	neutral	0,5	neutral	2,21	neutral	-2,76	deleterious	-8,89	medium_impact	2,06	neutral	0,74	damaging	0,13	deleterious	3,96	23,6	0,28	0,45	disease	0,7	disease	0,78	disease	0,7	disease	0,67	3	neutral	0,76	neutral	0,36	NA	0	deleterious	0,74	low_impact	-1,23	medium_impact	0,2	medium_impact	0,91	0,15	0,8	15,69	15,43	N	0,39	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12025	12025	C	A	MI.18976	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1266	422	H	Q	caC/caA	4,4	0,96	0	possibly_damaging	0,85	neutral	0,2	neutral	2,26	neutral	-0,75	deleterious	-6,35	medium_impact	2,54	neutral	0,7	damaging	0,13	deleterious	4,05	23,7	0,45	0,55	disease	0,8	disease	0,71	disease	0,61	disease	0,67	3	neutral	0,91	neutral	0,18	NA	0	deleterious	0,78	low_impact	-1,43	medium_impact	-0,14	medium_impact	1,39	0,4	0,8	15,69	15,43	N	0,49	N	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12025	12025	C	G	MI.18977	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1266	422	H	Q	caC/caG	4,4	0,96	0	possibly_damaging	0,85	neutral	0,2	neutral	2,26	neutral	-0,75	deleterious	-6,35	medium_impact	2,54	neutral	0,7	damaging	0,13	deleterious	3,65	23,2	0,45	0,55	disease	0,8	disease	0,71	disease	0,61	disease	0,67	3	neutral	0,91	neutral	0,18	NA	0	deleterious	0,78	low_impact	-1,43	medium_impact	-0,14	medium_impact	1,39	0,4	0,8	15,69	15,43	N	0,49	N	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12026	12026	A	G	MI.18978	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1267	423	I	V	Att/Gtt	-1,81	0	0,04	benign	0	neutral	0,3	neutral	2,36	neutral	-1,59	neutral	-0,37	low_impact	1,75	neutral	0,77	neutral	0,96	deleterious	-0,05	2,16	0,62	0,65	neutral	0,45	neutral	0,18	neutral	0,4	neutral	0,34	3	neutral	0,7	deleterious	0,65	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	0	medium_impact	0,61	0,25	0,8	34,2	23,16	P	0,58	P	0,5	polymorphism	1	0,01	rs202136725	.	.	.	.	.	.	.	.	A12026G	DM	+	-	Reported	2
chrM	12026	12026	A	T	MI.18979	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1267	423	I	F	Att/Ttt	-1,81	0	0,04	benign	0,18	neutral	0,26	neutral	2,27	neutral	-2,42	neutral	-2,31	low_impact	1,62	neutral	0,7	neutral	0,51	deleterious	1,83	15,14	0,2	0,45	neutral	0,48	disease	0,52	neutral	0,23	neutral	0,47	1	neutral	0,69	deleterious	0,54	neutral	-6	neutral	0,28	medium_impact	-0,1	medium_impact	-0,05	medium_impact	0,48	0,26	0,8	34,2	23,16	N	0,41	N	0,43	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5913	5913	G	A	MI.1898	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	10	4	D	N	Gac/Aac	-5,89	0	0	benign	0	neutral	0,47	neutral	3,02	neutral	0,01	neutral	0,2	neutral_impact	-1,61	neutral	0,85	neutral	0,98	neutral	-0,59	0,14	0,73	0,75	neutral	0,15	neutral	0,04	neutral	0,13	neutral	0,22	6	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,05	high_impact	2,07	medium_impact	0,16	low_impact	-2,59	0,47	0,9	13,26	25,03	N	0,53	P	0	polymorphism	1	0	rs201617272	.	.	.	.	.	.	.	.	G5913A	Prostate Cancer/hypertension	+	-	Reported	3
chrM	12026	12026	A	C	MI.18980	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1267	423	I	L	Att/Ctt	-1,81	0	0,04	benign	0,01	neutral	0,87	neutral	2,35	neutral	-1,36	neutral	-0,49	neutral_impact	0,23	neutral	0,74	neutral	0,78	deleterious	0,1	3,6	0,43	0,55	neutral	0,38	neutral	0,13	neutral	0,14	neutral	0,26	5	neutral	0,1	deleterious	0,93	neutral	-6	neutral	0,1	medium_impact	1,16	medium_impact	0,67	medium_impact	-0,9	0,31	0,8	34,2	23,16	N	0,39	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12027	12027	T	C	MI.18981	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1268	423	I	T	aTt/aCt	0,95	0	0	benign	0	neutral	0,28	neutral	2,26	neutral	-1,31	neutral	-1,68	neutral_impact	0,04	neutral	0,83	neutral	0,97	deleterious	0,14	3,99	0,23	0,45	neutral	0,4	neutral	0,41	neutral	0,24	neutral	0,47	1	neutral	0,72	deleterious	0,64	neutral	-6	neutral	0,16	high_impact	2,1	medium_impact	-0,03	low_impact	-1,09	0,12	0,8	34,2	23,16	N	0,47	N	0,06	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	T12027C	SZ-associated	.	.	Reported	2
chrM	12027	12027	T	G	MI.18982	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1268	423	I	S	aTt/aGt	0,95	0	0	benign	0,05	neutral	0,07	neutral	2,22	neutral	-0,7	deleterious	-2,84	low_impact	1,49	neutral	0,74	neutral	0,66	deleterious	2,41	18,89	0,14	0,4	disease	0,72	disease	0,62	neutral	0,3	disease	0,53	1	neutral	0,93	deleterious	0,51	neutral	-6	neutral	0,26	medium_impact	0,48	medium_impact	-0,43	medium_impact	0,35	0,12	0,8	34,2	23,16	N	0,41	N	0,46	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12027	12027	T	A	MI.18983	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1268	423	I	N	aTt/aAt	0,95	0	0	benign	0,14	neutral	0,21	neutral	2,18	neutral	-1,23	deleterious	-3,84	low_impact	1,14	neutral	0,8	neutral	0,59	deleterious	2,61	20,3	0,18	0,45	disease	0,87	disease	0,67	neutral	0,45	disease	0,6	2	neutral	0,76	deleterious	0,54	neutral	-6	neutral	0,43	medium_impact	0,02	medium_impact	-0,12	medium_impact	0	0,09	0,8	34,2	23,16	N	0,31	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12028	12028	T	A	MI.18984	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1269	423	I	M	atT/atA	0,95	0	0	benign	0,01	neutral	0,35	neutral	2,21	deleterious	-4,26	neutral	-0,87	neutral_impact	0,56	neutral	0,75	neutral	0,97	deleterious	0,45	7,01	0,47	0,55	neutral	0,46	neutral	0,17	neutral	0,17	neutral	0,3	4	neutral	0,64	deleterious	0,67	neutral	-6	neutral	0,39	medium_impact	1,16	medium_impact	0,05	medium_impact	-0,57	0,34	0,8	34,2	23,16	P	0,57	P	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12028	12028	T	G	MI.18985	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1269	423	I	M	atT/atG	0,95	0	0	benign	0,01	neutral	0,35	neutral	2,21	deleterious	-4,26	neutral	-0,87	neutral_impact	0,56	neutral	0,75	neutral	0,97	deleterious	0,21	4,77	0,47	0,55	neutral	0,46	neutral	0,17	neutral	0,17	neutral	0,3	4	neutral	0,64	deleterious	0,67	neutral	-6	neutral	0,39	medium_impact	1,16	medium_impact	0,05	medium_impact	-0,57	0,34	0,8	34,2	23,16	P	0,57	P	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12029	12029	A	G	MI.18986	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1270	424	N	D	Aac/Gac	-8,49	0	0	benign	0,01	neutral	0,18	neutral	2,25	neutral	-1,96	neutral	-1,81	medium_impact	2,26	neutral	0,78	neutral	0,48	deleterious	0,7	8,82	0,75	0,8	disease	0,62	neutral	0,29	neutral	0,35	disease	0,55	1	neutral	0,82	deleterious	0,59	neutral	-3	neutral	0,15	medium_impact	1,16	medium_impact	-0,17	medium_impact	1,11	0,34	0,8	32,9	28,3	N	0,4	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12029	12029	A	T	MI.18987	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1270	424	N	Y	Aac/Tac	-8,49	0	0	benign	0	neutral	1	neutral	2,19	neutral	-1,09	neutral	-1,29	low_impact	0,82	neutral	0,79	neutral	0,75	neutral	-0,83	0,04	0,21	0,45	disease	0,83	neutral	0,31	neutral	0,17	disease	0,62	2	neutral	0	deleterious	1	neutral	-6	neutral	0,24	high_impact	2,1	high_impact	1,88	medium_impact	-0,32	0,27	0,8	32,9	28,3	N	0,31	N	0,85	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12029	12029	A	C	MI.18988	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1270	424	N	H	Aac/Cac	-8,49	0	0	benign	0,04	neutral	0,49	neutral	2,21	deleterious	-3,45	neutral	-0,58	low_impact	1,06	neutral	0,78	neutral	0,91	neutral	-0,65	0,1	0,58	0,65	disease	0,76	neutral	0,24	neutral	0,2	disease	0,57	1	neutral	0,47	deleterious	0,73	neutral	-6	neutral	0,22	medium_impact	0,58	medium_impact	0,19	medium_impact	-0,08	0,2	0,8	32,9	28,3	N	0,37	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12030	12030	A	C	MI.18989	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1271	424	N	T	aAc/aCc	0,49	0	0	benign	0	neutral	0,43	neutral	2,26	neutral	-1,57	neutral	-1,12	neutral_impact	-0,5	neutral	0,7	neutral	0,92	neutral	-0,16	1,33	0,53	0,6	neutral	0,39	neutral	0,16	neutral	0,15	neutral	0,29	4	neutral	0,57	deleterious	0,72	neutral	-6	neutral	0,09	high_impact	2,1	medium_impact	0,13	low_impact	-1,62	0,28	0,8	32,9	28,3	N	0,52	P	0,03	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5913	5913	G	T	MI.1899	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	10	4	D	Y	Gac/Tac	-5,89	0	0	benign	0	neutral	0,06	neutral	3,03	neutral	-1,83	neutral	-0,05	neutral_impact	-0,98	neutral	0,69	neutral	0,65	deleterious	2,16	17,27	0,37	0,55	neutral	0,45	neutral	0,25	disease	0,54	neutral	0,45	1	neutral	0,94	deleterious	0,53	neutral	-6	neutral	0,13	high_impact	2,07	medium_impact	-0,47	low_impact	-2	0,27	0,9	13,26	25,03	N	0,46	N	0,66	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12030	12030	A	T	MI.18990	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1271	424	N	I	aAc/aTc	0,49	0	0	benign	0	neutral	0,42	neutral	2,2	neutral	-0,72	neutral	-1,54	neutral_impact	-0,38	neutral	0,71	neutral	0,97	deleterious	0,27	5,37	0,26	0,45	disease	0,75	neutral	0,25	neutral	0,18	disease	0,58	2	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,15	high_impact	2,1	medium_impact	0,12	low_impact	-1,5	0,33	0,8	32,9	28,3	N	0,47	N	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12030	12030	A	G	MI.18991	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1271	424	N	S	aAc/aGc	0,49	0	0	benign	0	neutral	0,44	neutral	2,28	neutral	-0,13	neutral	-0,9	neutral_impact	0,16	neutral	0,73	neutral	0,87	neutral	-0,44	0,31	0,77	0,8	neutral	0,37	neutral	0,17	neutral	0,19	neutral	0,3	4	neutral	0,56	deleterious	0,72	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	0,14	medium_impact	-0,97	0,29	0,8	32,9	28,3	N	0,51	P	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12031	12031	C	G	MI.18992	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1272	424	N	K	aaC/aaG	-1,58	0	0	benign	0	neutral	0,3	neutral	2,33	neutral	-0,96	neutral	-0,95	neutral_impact	-0,14	neutral	0,83	neutral	0,97	deleterious	0,57	7,93	0,65	0,7	neutral	0,45	neutral	0,17	neutral	0,21	neutral	0,3	4	neutral	0,7	deleterious	0,65	neutral	-6	neutral	0,11	high_impact	2,1	medium_impact	0	low_impact	-1,26	0,47	0,8	32,9	28,3	N	0,47	N	0,37	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12031	12031	C	A	MI.18993	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1272	424	N	K	aaC/aaA	-1,58	0	0	benign	0	neutral	0,3	neutral	2,33	neutral	-0,96	neutral	-0,95	neutral_impact	-0,14	neutral	0,83	neutral	0,97	neutral	1,05	10,95	0,65	0,7	neutral	0,45	neutral	0,17	neutral	0,21	neutral	0,3	4	neutral	0,7	deleterious	0,65	neutral	-6	neutral	0,11	high_impact	2,1	medium_impact	0	low_impact	-1,26	0,47	0,8	32,9	28,3	N	0,47	N	0,37	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12032	12032	A	T	MI.18994	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1273	425	N	Y	Aac/Tac	-6,19	0	0	probably_damaging	0,94	neutral	1	neutral	2,14	deleterious	-5,18	deleterious	-3,25	medium_impact	1,96	neutral	0,84	neutral	0,61	deleterious	2,32	18,28	0,19	0,45	disease	0,9	neutral	0,49	neutral	0,36	disease	0,64	3	neutral	0,94	deleterious	0,53	deleterious	1	deleterious	0,75	low_impact	-1,84	high_impact	1,88	medium_impact	0,81	0,27	0,8	21,57	18,65	N	0,2	N	0,83	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12032	12032	A	C	MI.18995	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1273	425	N	H	Aac/Cac	-6,19	0	0	probably_damaging	0,92	neutral	0,52	neutral	2,17	deleterious	-3,48	neutral	-2,22	low_impact	1,76	neutral	0,82	neutral	0,74	deleterious	1,91	15,66	0,58	0,65	disease	0,87	neutral	0,34	neutral	0,25	disease	0,65	3	neutral	0,91	neutral	0,3	neutral	-2	deleterious	0,7	low_impact	-1,71	medium_impact	0,22	medium_impact	0,62	0,18	0,8	21,57	18,65	N	0,31	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12032	12032	A	G	MI.18996	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1273	425	N	D	Aac/Gac	-6,19	0	0	benign	0,42	neutral	0,22	neutral	2,2	neutral	-1,35	neutral	-1,96	medium_impact	2,6	neutral	0,8	neutral	0,63	deleterious	2,7	20,8	0,75	0,8	disease	0,8	neutral	0,34	neutral	0,37	disease	0,65	3	neutral	0,75	neutral	0,4	neutral	-3	deleterious	0,7	medium_impact	-0,59	medium_impact	-0,11	medium_impact	1,45	0,42	0,8	21,57	18,65	N	0,39	N	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12033	12033	A	T	MI.18997	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1274	425	N	I	aAc/aTc	-0,66	0	0	possibly_damaging	0,84	neutral	0,47	neutral	2,15	deleterious	-4,88	deleterious	-3,49	low_impact	1,66	neutral	0,78	neutral	0,91	deleterious	2,97	22,1	0,24	0,45	disease	0,67	neutral	0,5	neutral	0,22	neutral	0,45	1	neutral	0,83	neutral	0,32	neutral	-3	deleterious	0,71	low_impact	-1,39	medium_impact	0,17	medium_impact	0,52	0,23	0,8	21,57	18,65	N	0,34	N	0,8	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12033	12033	A	G	MI.18998	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1274	425	N	S	aAc/aGc	-0,66	0	0	benign	0,06	neutral	0,8	neutral	2,26	neutral	-1,92	neutral	-0,61	low_impact	0,88	neutral	0,74	neutral	1	neutral	1,21	11,8	0,73	0,75	neutral	0,44	neutral	0,1	neutral	0,18	neutral	0,28	4	neutral	0,11	deleterious	0,87	neutral	-6	deleterious	0,61	medium_impact	0,41	medium_impact	0,54	medium_impact	-0,26	0,33	0,8	21,57	18,65	N	0,44	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12033	12033	A	C	MI.18999	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1274	425	N	T	aAc/aCc	-0,66	0	0	benign	0,42	neutral	0,5	neutral	2,22	neutral	-1,58	neutral	-1,54	low_impact	1,12	neutral	0,71	neutral	0,93	deleterious	2,09	16,8	0,53	0,6	disease	0,56	neutral	0,25	neutral	0,17	disease	0,55	1	neutral	0,45	deleterious	0,54	neutral	-6	deleterious	0,64	medium_impact	-0,59	medium_impact	0,2	medium_impact	-0,02	0,28	0,8	21,57	18,65	N	0,42	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8534	8534	A	T	MI.19	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	8	3	E	V	gAa/gTa	-0,1	0,06	0	probably_damaging	0,98	neutral	0,59	neutral	4,68	neutral	-0,07	neutral	-2,36	neutral_impact	0,64	neutral	0,8	neutral	0,66	deleterious	8,43	35	0,43	0,65	disease	0,59	neutral	0,17	neutral	0,15	neutral	0,39	2	neutral	0,98	neutral	0,31	neutral	-2	deleterious	0,66	low_impact	-2,36	medium_impact	0,38	medium_impact	-0,55	0,81	0,9	15,93	14,48	N	0,29	N	0,85	polymorphism	0,98	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8616	8616	G	T	MI.190	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	90	30	L	F	ttG/ttT	7,53	0,96	0,02	probably_damaging	1	neutral	0,39	neutral	4,31	neutral	-0,71	deleterious	-3,18	low_impact	1,63	neutral	0,91	neutral	0,87	deleterious	2,33	18,35	0,41	0,65	disease	0,66	neutral	0,4	neutral	0,15	disease	0,62	2	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,18	medium_impact	0,3	0,59	0,9	17,7	14,1	N	0,5	N	0,87	polymorphism	1	0,05	rs41427749	Likely benign	not_provided	RCV000224510.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	5914	5914	A	C	MI.1900	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	11	4	D	A	gAc/gCc	2,9	0,03	0	benign	0	neutral	0,15	neutral	3,05	neutral	0,42	neutral	0,04	neutral_impact	-1,36	neutral	0,71	neutral	0,72	deleterious	2,1	16,88	0,42	0,55	neutral	0,19	neutral	0,11	neutral	0,37	neutral	0,26	5	neutral	0,85	deleterious	0,58	neutral	-6	neutral	0,07	high_impact	2,07	medium_impact	-0,23	low_impact	-2,36	0,38	0,9	13,26	25,03	N	0,53	P	0,41	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12034	12034	C	A	MI.19000	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1275	425	N	K	aaC/aaA	0,03	0	0	possibly_damaging	0,56	neutral	0,38	neutral	2,26	neutral	-0,78	neutral	-2,19	medium_impact	1,96	neutral	0,79	neutral	0,67	deleterious	3,4	23	0,65	0,7	disease	0,71	neutral	0,4	neutral	0,39	disease	0,64	3	neutral	0,63	neutral	0,41	NA	0	deleterious	0,71	medium_impact	-0,82	medium_impact	0,08	medium_impact	0,81	0,42	0,8	21,57	18,65	N	0,34	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12034	12034	C	G	MI.19001	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1275	425	N	K	aaC/aaG	0,03	0	0	possibly_damaging	0,56	neutral	0,38	neutral	2,26	neutral	-0,78	neutral	-2,19	medium_impact	1,96	neutral	0,79	neutral	0,67	deleterious	2,88	21,8	0,65	0,7	disease	0,71	neutral	0,4	neutral	0,39	disease	0,64	3	neutral	0,63	neutral	0,41	NA	0	deleterious	0,71	medium_impact	-0,82	medium_impact	0,08	medium_impact	0,81	0,42	0,8	21,57	18,65	N	0,34	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12035	12035	A	G	MI.19002	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1276	426	M	V	Ata/Gta	-9,87	0	0	benign	0	neutral	0,41	neutral	2,38	neutral	4,22	neutral	0,3	low_impact	1,46	neutral	0,78	neutral	0,96	neutral	1,28	12,17	0,44	0,55	disease	0,55	neutral	0,22	neutral	0,27	neutral	0,47	1	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,41	high_impact	2,1	medium_impact	0,11	medium_impact	0,32	0,28	0,8	28,98	29,5	N	0,43	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12035	12035	A	T	MI.19003	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1276	426	M	L	Ata/Tta	-9,87	0	0	benign	0	neutral	1	neutral	2,45	neutral	2,86	neutral	0,46	low_impact	0,8	neutral	0,68	neutral	0,97	deleterious	0,25	5,15	0,33	0,5	disease	0,68	neutral	0,09	neutral	0,19	neutral	0,36	3	neutral	0	deleterious	1	neutral	-6	neutral	0,35	high_impact	2,1	high_impact	1,88	medium_impact	-0,33	0,21	0,8	28,98	29,5	N	0,44	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12035	12035	A	C	MI.19004	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1276	426	M	L	Ata/Cta	-9,87	0	0	benign	0	neutral	1	neutral	2,45	neutral	2,86	neutral	0,46	low_impact	0,8	neutral	0,68	neutral	0,97	deleterious	0,17	4,35	0,33	0,5	disease	0,68	neutral	0,09	neutral	0,19	neutral	0,36	3	neutral	0	deleterious	1	neutral	-6	neutral	0,35	high_impact	2,1	high_impact	1,88	medium_impact	-0,33	0,21	0,8	28,98	29,5	N	0,45	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12036	12036	T	A	MI.19005	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1277	426	M	K	aTa/aAa	-0,43	0	0	benign	0,29	neutral	0,15	neutral	2,29	neutral	2,42	deleterious	-3,65	medium_impact	3,08	neutral	0,73	neutral	0,52	deleterious	4,03	23,6	0,15	0,4	disease	0,75	neutral	0,49	disease	0,51	disease	0,58	2	neutral	0,82	neutral	0,43	neutral	-3	deleterious	0,68	medium_impact	-0,35	medium_impact	-0,22	medium_impact	1,92	0,28	0,8	28,98	29,5	N	0,42	N	0,89	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12036	12036	T	C	MI.19006	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1277	426	M	T	aTa/aCa	-0,43	0	0	benign	0,12	neutral	0,3	neutral	2,33	neutral	2,76	neutral	-2,23	low_impact	0,92	neutral	0,67	neutral	0,84	deleterious	1,9	15,6	0,22	0,45	neutral	0,46	neutral	0,28	neutral	0,28	neutral	0,45	1	neutral	0,66	deleterious	0,59	neutral	-6	deleterious	0,59	medium_impact	0,1	medium_impact	0	medium_impact	-0,22	0,09	0,8	28,98	29,5	N	0,44	N	0,64	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12037	12037	A	C	MI.19007	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1278	426	M	I	atA/atC	3,71	0,33	0	benign	0	neutral	0,63	neutral	2,37	neutral	4,61	neutral	0,85	neutral_impact	0,43	neutral	0,77	neutral	0,98	neutral	0,98	10,57	0,35	0,5	disease	0,51	neutral	0,09	neutral	0,18	neutral	0,27	5	neutral	0,37	deleterious	0,82	neutral	-6	deleterious	0,48	high_impact	2,1	medium_impact	0,33	medium_impact	-0,7	0,26	0,8	28,98	29,5	N	0,48	N	0,13	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12037	12037	A	T	MI.19008	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1278	426	M	I	atA/atT	3,71	0,33	0	benign	0	neutral	0,63	neutral	2,37	neutral	4,61	neutral	0,85	neutral_impact	0,43	neutral	0,77	neutral	0,98	neutral	1,06	10,99	0,35	0,5	disease	0,51	neutral	0,09	neutral	0,18	neutral	0,27	5	neutral	0,37	deleterious	0,82	neutral	-6	deleterious	0,48	high_impact	2,1	medium_impact	0,33	medium_impact	-0,7	0,26	0,8	28,98	29,5	N	0,49	N	0,13	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12038	12038	A	C	MI.19009	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1279	427	K	Q	Aaa/Caa	-8,95	0	0	possibly_damaging	0,8	neutral	0,71	neutral	2,21	neutral	-1,02	neutral	-0,64	low_impact	0,87	neutral	0,72	neutral	0,96	deleterious	1,82	15,09	0,46	0,55	disease	0,65	neutral	0,17	neutral	0,14	neutral	0,4	2	neutral	0,76	neutral	0,46	neutral	-3	deleterious	0,67	low_impact	-1,28	medium_impact	0,42	medium_impact	-0,27	0,24	0,8	22,44	24,22	N	0,37	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5914	5914	A	T	MI.1901	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	11	4	D	V	gAc/gTc	2,9	0,03	0	benign	0,02	neutral	0,06	neutral	3,07	neutral	-0,63	neutral	0,04	neutral_impact	-2	neutral	0,71	neutral	0,68	neutral	1,33	12,41	0,38	0,55	neutral	0,24	neutral	0,16	neutral	0,42	neutral	0,29	4	neutral	0,94	deleterious	0,52	neutral	-6	neutral	0,1	medium_impact	0,83	medium_impact	-0,47	low_impact	-2,95	0,28	0,9	13,26	25,03	N	0,5	N	0,71	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12038	12038	A	G	MI.19010	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1279	427	K	E	Aaa/Gaa	-8,95	0	0	benign	0,42	neutral	0,97	neutral	2,25	neutral	-0,79	neutral	-0,75	low_impact	1,2	neutral	0,75	neutral	0,73	deleterious	2,12	16,97	0,23	0,45	disease	0,71	neutral	0,31	neutral	0,18	disease	0,63	3	neutral	0,39	deleterious	0,78	neutral	-6	deleterious	0,72	medium_impact	-0,59	medium_impact	1,05	medium_impact	0,06	0,42	0,8	22,44	24,22	N	0,34	N	0,47	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12039	12039	A	T	MI.19011	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1280	427	K	M	aAa/aTa	-0,89	0	0	probably_damaging	0,94	neutral	0,2	neutral	2,12	deleterious	-4,46	neutral	-1,98	medium_impact	1,97	neutral	0,82	neutral	0,67	deleterious	3,9	23,5	0,18	0,45	neutral	0,39	neutral	0,17	neutral	0,32	neutral	0,33	4	neutral	0,96	neutral	0,13	deleterious	1	deleterious	0,65	low_impact	-1,84	medium_impact	-0,14	medium_impact	0,82	0,17	0,8	22,44	24,22	N	0,45	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12039	12039	A	C	MI.19012	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1280	427	K	T	aAa/aCa	-0,89	0	0	possibly_damaging	0,56	neutral	0,68	neutral	2,19	neutral	-0,9	neutral	-0,96	low_impact	0,82	neutral	0,72	neutral	0,98	deleterious	1,89	15,5	0,27	0,45	neutral	0,38	neutral	0,18	neutral	0,15	neutral	0,3	4	neutral	0,48	deleterious	0,56	neutral	-3	deleterious	0,64	medium_impact	-0,82	medium_impact	0,39	medium_impact	-0,32	0,12	0,8	22,44	24,22	N	0,44	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12040	12040	A	C	MI.19013	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1281	427	K	N	aaA/aaC	-0,43	0	0	benign	0,03	neutral	0,7	neutral	2,2	neutral	-1,78	neutral	-0,52	low_impact	1,07	neutral	0,71	neutral	0,97	deleterious	2,19	17,47	0,61	0,65	disease	0,69	neutral	0,15	neutral	0,15	neutral	0,4	2	neutral	0,24	deleterious	0,84	neutral	-6	deleterious	0,7	medium_impact	0,7	medium_impact	0,41	medium_impact	-0,07	0,37	0,8	22,44	24,22	N	0,41	N	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12040	12040	A	T	MI.19014	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1281	427	K	N	aaA/aaT	-0,43	0	0	benign	0,03	neutral	0,7	neutral	2,2	neutral	-1,78	neutral	-0,52	low_impact	1,07	neutral	0,71	neutral	0,97	deleterious	2,27	17,95	0,61	0,65	disease	0,69	neutral	0,15	neutral	0,15	neutral	0,4	2	neutral	0,24	deleterious	0,84	neutral	-6	deleterious	0,7	medium_impact	0,7	medium_impact	0,41	medium_impact	-0,07	0,37	0,8	22,44	24,22	N	0,41	N	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12041	12041	C	G	MI.19015	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1282	428	P	A	Ccc/Gcc	-5,04	0	0	probably_damaging	1	neutral	0,41	neutral	2,23	neutral	-2,87	deleterious	-7,12	medium_impact	3,25	neutral	0,76	neutral	0,57	deleterious	3,22	22,7	0,49	0,55	disease	0,74	disease	0,54	disease	0,63	disease	0,57	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	0,11	high_impact	2,09	0,4	0,8	47,71	9,38	N	0,32	N	0,74	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12041	12041	C	T	MI.19016	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1282	428	P	S	Ccc/Tcc	-5,04	0	0	probably_damaging	1	neutral	0,56	neutral	2,25	neutral	-0,29	deleterious	-7,09	medium_impact	2,84	neutral	0,76	neutral	0,57	deleterious	3,97	23,6	0,46	0,55	neutral	0,42	disease	0,66	disease	0,61	neutral	0,48	1	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	0,26	medium_impact	1,68	0,11	0,8	47,71	9,38	N	0,26	N	0,68	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12041	12041	C	A	MI.19017	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1282	428	P	T	Ccc/Acc	-5,04	0	0	probably_damaging	1	neutral	0,38	neutral	2,22	neutral	-2,2	deleterious	-7,13	high_impact	3,6	neutral	0,69	neutral	0,52	deleterious	3,99	23,6	0,33	0,5	neutral	0,41	disease	0,76	disease	0,51	disease	0,56	1	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,73	low_impact	-3,54	medium_impact	0,08	high_impact	2,44	0,33	0,8	47,71	9,38	N	0,37	N	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12042	12042	C	T	MI.19018	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1283	428	P	L	cCc/cTc	4,4	0,98	0	probably_damaging	1	neutral	0,61	neutral	2,19	neutral	-0,67	deleterious	-8,95	medium_impact	3,06	neutral	0,7	neutral	0,46	deleterious	4,49	24,3	0,24	0,45	neutral	0,42	disease	0,76	neutral	0,44	disease	0,52	0	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	0,31	medium_impact	1,9	0,51	0,8	47,71	9,38	N	0,48	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12042	12042	C	A	MI.19019	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1283	428	P	H	cCc/cAc	4,4	0,98	0	probably_damaging	1	neutral	0,36	neutral	2,17	deleterious	-4,83	deleterious	-8,03	high_impact	4,16	neutral	0,71	neutral	0,39	deleterious	4,33	24	0,3	0,45	disease	0,81	disease	0,8	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,79	low_impact	-3,54	medium_impact	0,06	high_impact	2,99	0,18	0,8	47,71	9,38	P	0,63	P	0,7	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5914	5914	A	G	MI.1902	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	11	4	D	G	gAc/gGc	2,9	0,03	0	benign	0,01	neutral	0,05	neutral	2,99	neutral	-0,89	neutral	-0,08	neutral_impact	-0,98	neutral	0,68	neutral	0,57	deleterious	2,53	19,65	0,43	0,55	neutral	0,32	neutral	0,15	neutral	0,4	neutral	0,28	4	neutral	0,95	deleterious	0,52	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	-0,52	low_impact	-2	0,41	0,9	13,26	25,03	N	0,53	P	0,23	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12042	12042	C	G	MI.19020	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1283	428	P	R	cCc/cGc	4,4	0,98	0	probably_damaging	1	neutral	0,25	neutral	2,23	deleterious	-4,05	deleterious	-8,04	high_impact	4,16	neutral	0,63	neutral	0,45	deleterious	3,77	23,4	0,17	0,45	disease	0,75	disease	0,83	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	-0,07	high_impact	2,99	0,21	0,8	47,71	9,38	P	0,63	P	0,62	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12044	12044	T	A	MI.19021	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1285	429	S	T	Tca/Aca	-10,56	0	0	benign	0,28	neutral	0,42	neutral	2,26	neutral	-0,97	neutral	-0,72	neutral_impact	0,51	neutral	0,77	neutral	0,99	deleterious	2,19	17,48	0,57	0,65	neutral	0,5	neutral	0,17	neutral	0,19	neutral	0,24	5	neutral	0,49	deleterious	0,57	neutral	-6	deleterious	0,63	medium_impact	-0,33	medium_impact	0,12	medium_impact	-0,62	0,38	0,8	23,75	18,84	N	0,49	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12044	12044	T	G	MI.19022	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1285	429	S	A	Tca/Gca	-10,56	0	0	benign	0,17	neutral	0,5	neutral	2,28	neutral	-1,73	neutral	-1,84	low_impact	1,49	neutral	0,78	neutral	0,7	deleterious	3,76	23,3	0,56	0,6	neutral	0,44	neutral	0,33	neutral	0,46	neutral	0,48	1	neutral	0,4	deleterious	0,67	neutral	-6	deleterious	0,62	medium_impact	-0,07	medium_impact	0,2	medium_impact	0,35	0,2	0,8	23,75	18,84	N	0,35	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12044	12044	T	C	MI.19023	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1285	429	S	P	Tca/Cca	-10,56	0	0	benign	0	neutral	0,2	neutral	2,19	neutral	-0,26	deleterious	-3,33	neutral_impact	0,77	neutral	0,75	neutral	0,64	deleterious	4,02	23,6	0,19	0,45	disease	0,67	disease	0,76	neutral	0,27	disease	0,53	1	neutral	0,8	deleterious	0,6	neutral	-6	deleterious	0,78	high_impact	2,1	medium_impact	-0,14	medium_impact	-0,36	0,12	0,8	23,75	18,84	N	0,37	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12045	12045	C	G	MI.19024	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1286	429	S	W	tCa/tGa	-1,35	0	0	possibly_damaging	0,88	neutral	0,18	neutral	2,15	deleterious	-6,67	deleterious	-4,36	medium_impact	2,75	neutral	0,76	neutral	0,4	deleterious	4,5	24,3	0,08	0,35	disease	0,79	disease	0,77	disease	0,67	disease	0,76	5	neutral	0,93	neutral	0,15	NA	0	deleterious	0,77	low_impact	-1,53	medium_impact	-0,17	medium_impact	1,6	0,06	0,8	23,75	18,84	N	0,31	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12045	12045	C	T	MI.19025	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1286	429	S	L	tCa/tTa	-1,35	0	0	benign	0,01	neutral	0,7	neutral	2,25	deleterious	-3,57	deleterious	-3,38	low_impact	1,85	neutral	0,78	neutral	0,57	deleterious	4,71	24,6	0,24	0,45	disease	0,7	disease	0,63	neutral	0,46	disease	0,53	1	neutral	0,28	deleterious	0,85	neutral	-6	deleterious	0,68	medium_impact	1,16	medium_impact	0,41	medium_impact	0,7	0,32	0,8	23,75	18,84	N	0,23	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12047	12047	T	C	MI.19026	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1288	430	F	L	Ttc/Ctc	-12,4	0	0	benign	0,01	neutral	0,59	neutral	2,37	neutral	-1,27	deleterious	-3,88	low_impact	1,33	neutral	0,75	neutral	0,77	neutral	1,04	10,91	0,22	0,45	NA	NA	disease	0,53	neutral	0,46	neutral	0,46	1	neutral	0,4	deleterious	0,79	neutral	-6	neutral	0,13	medium_impact	1,16	medium_impact	0,29	medium_impact	0,19	0,64	0,8	23,31	21,92	N	0,33	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12047	12047	T	A	MI.19027	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1288	430	F	I	Ttc/Atc	-12,4	0	0	benign	0,1	neutral	0,38	neutral	2,33	deleterious	-3,01	deleterious	-3,93	medium_impact	2,65	neutral	0,74	neutral	0,54	deleterious	2,58	20	0,24	0,45	NA	NA	disease	0,7	neutral	0,47	neutral	0,49	0	neutral	0,56	deleterious	0,64	neutral	-3	neutral	0,17	medium_impact	0,18	medium_impact	0,08	medium_impact	1,5	0,46	0,8	23,31	21,92	N	0,41	N	0,74	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12047	12047	T	G	MI.19028	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1288	430	F	V	Ttc/Gtc	-12,4	0	0	benign	0,16	neutral	0,55	neutral	2,34	neutral	-2,6	deleterious	-4,44	medium_impact	2,3	neutral	0,75	neutral	0,54	deleterious	2,26	17,91	0,24	0,45	NA	NA	disease	0,7	neutral	0,49	disease	0,51	0	neutral	0,34	deleterious	0,7	neutral	-3	neutral	0,16	medium_impact	-0,04	medium_impact	0,25	medium_impact	1,15	0,5	0,8	23,31	21,92	N	0,29	N	0,81	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12048	12048	T	G	MI.19029	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1289	430	F	C	tTc/tGc	0,72	0	0	possibly_damaging	0,74	neutral	0,15	neutral	2,25	deleterious	-5,08	deleterious	-5,1	medium_impact	3	neutral	0,72	neutral	0,42	deleterious	2,42	18,98	0,1	0,4	NA	NA	disease	0,77	disease	0,62	disease	0,75	5	neutral	0,89	neutral	0,21	NA	0	neutral	0,38	low_impact	-1,14	medium_impact	-0,22	medium_impact	1,84	0,35	0,8	23,31	21,92	N	0,37	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5915	5915	C	G	MI.1903	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	12	4	D	E	gaC/gaG	1,05	0,02	0	benign	0,02	neutral	0,12	neutral	3,03	neutral	0,83	neutral	0,04	neutral_impact	-1,75	neutral	0,74	neutral	0,68	deleterious	0,65	8,51	0,54	0,6	neutral	0,15	neutral	0,09	neutral	0,12	neutral	0,27	5	neutral	0,88	deleterious	0,55	neutral	-6	neutral	0,07	medium_impact	0,83	medium_impact	-0,29	low_impact	-2,72	0,33	0,9	13,26	25,03	P	0,58	P	0,2	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12048	12048	T	C	MI.19030	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1289	430	F	S	tTc/tCc	0,72	0	0	benign	0,02	neutral	0,48	neutral	2,35	neutral	-0,54	deleterious	-4,54	low_impact	1,8	neutral	0,73	neutral	0,77	neutral	1,38	12,7	0,16	0,45	NA	NA	disease	0,61	neutral	0,41	neutral	0,46	1	neutral	0,5	deleterious	0,73	neutral	-6	neutral	0,17	medium_impact	0,87	medium_impact	0,18	medium_impact	0,66	0,33	0,8	23,31	21,92	N	0,37	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12048	12048	T	A	MI.19031	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1289	430	F	Y	tTc/tAc	0,72	0	0	benign	0,16	neutral	1	neutral	2,28	deleterious	-3,97	neutral	-0,3	low_impact	1,36	neutral	0,72	neutral	0,97	neutral	1,08	11,1	0,23	0,45	NA	NA	neutral	0,43	neutral	0,28	neutral	0,21	6	neutral	0,16	deleterious	0,92	neutral	-6	neutral	0,19	medium_impact	-0,04	high_impact	1,88	medium_impact	0,22	0,31	0,8	23,31	21,92	N	0,34	N	0,68	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12049	12049	C	G	MI.19032	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1290	430	F	L	ttC/ttG	0,26	0	0	benign	0,01	neutral	0,59	neutral	2,37	neutral	-1,27	deleterious	-3,88	low_impact	1,33	neutral	0,75	neutral	0,77	neutral	1,3	12,28	0,22	0,45	NA	NA	disease	0,53	neutral	0,46	neutral	0,46	1	neutral	0,4	deleterious	0,79	neutral	-6	neutral	0,13	medium_impact	1,16	medium_impact	0,29	medium_impact	0,19	0,64	0,8	23,31	21,92	N	0,3	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12049	12049	C	A	MI.19033	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1290	430	F	L	ttC/ttA	0,26	0	0	benign	0,01	neutral	0,59	neutral	2,37	neutral	-1,27	deleterious	-3,88	low_impact	1,33	neutral	0,75	neutral	0,77	neutral	1,59	13,79	0,22	0,45	NA	NA	disease	0,53	neutral	0,46	neutral	0,46	1	neutral	0,4	deleterious	0,79	neutral	-6	neutral	0,13	medium_impact	1,16	medium_impact	0,29	medium_impact	0,19	0,64	0,8	23,31	21,92	N	0,31	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12050	12050	A	T	MI.19034	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1291	431	T	S	Aca/Tca	-2,73	0	0	probably_damaging	1	neutral	0,82	neutral	2,29	neutral	0,7	deleterious	-3,5	medium_impact	2	damaging	0,58	damaging	0,27	deleterious	2,24	17,78	0,44	0,55	disease	0,83	neutral	0,26	neutral	0,31	disease	0,57	1	deleterious	0,99	neutral	0,41	deleterious	1	deleterious	0,71	low_impact	-3,54	medium_impact	0,57	medium_impact	0,85	0,54	0,8	46,84	9,2	N	0,26	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12050	12050	A	G	MI.19035	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1291	431	T	A	Aca/Gca	-2,73	0	0	probably_damaging	1	neutral	0,1	neutral	2,27	neutral	-1,67	deleterious	-4,44	high_impact	3,52	damaging	0,47	damaging	0,14	deleterious	3,6	23,2	0,25	0,45	neutral	0,5	neutral	0,47	disease	0,65	neutral	0,46	1	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,68	low_impact	-3,54	medium_impact	-0,33	high_impact	2,36	0,33	0,8	46,84	9,2	N	0,42	N	0,68	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12050	12050	A	C	MI.19036	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1291	431	T	P	Aca/Cca	-2,73	0	0	probably_damaging	1	neutral	0,06	neutral	2,21	deleterious	-3,39	deleterious	-5,36	high_impact	3,52	damaging	0,36	damaging	0,08	deleterious	3,65	23,2	0,1	0,4	disease	0,91	disease	0,75	disease	0,64	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	-0,47	high_impact	2,36	0,3	0,8	46,84	9,2	N	0,49	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12051	12051	C	T	MI.19037	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1292	431	T	M	aCa/aTa	5,32	1	0	probably_damaging	1	neutral	0,13	neutral	2,19	deleterious	-3,96	deleterious	-5,36	medium_impact	3,27	damaging	0,43	damaging	0,08	deleterious	4,2	23,9	0,17	0,45	disease	0,75	disease	0,6	disease	0,69	disease	0,61	2	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,73	low_impact	-3,54	medium_impact	-0,26	high_impact	2,11	0,42	0,8	46,84	9,2	P	0,69	P	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12051	12051	C	A	MI.19038	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1292	431	T	K	aCa/aAa	5,32	1	0	probably_damaging	1	neutral	0,06	neutral	2,26	neutral	-1,22	deleterious	-5,35	high_impact	3,73	damaging	0,44	damaging	0,07	deleterious	4,58	24,4	0,12	0,4	disease	0,73	disease	0,8	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	-0,47	high_impact	2,56	0,37	0,8	46,84	9,2	P	0,72	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12053	12053	C	T	MI.19039	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1294	432	R	W	Cga/Tga	-1,58	0	0	probably_damaging	1	deleterious	0,02	neutral	2,06	deleterious	-6,01	deleterious	-7,24	high_impact	3,86	damaging	0,51	damaging	0,05	deleterious	5,36	25,9	0,07	0,35	disease	0,95	disease	0,79	disease	0,8	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,54	medium_impact	-0,75	high_impact	2,69	0,87	0,9	46,84	9,54	N	0,35	N	1	polymorphism	1	0,13	rs28639786	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5915	5915	C	A	MI.1904	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	12	4	D	E	gaC/gaA	1,05	0,02	0	benign	0,02	neutral	0,12	neutral	3,03	neutral	0,83	neutral	0,04	neutral_impact	-1,75	neutral	0,74	neutral	0,68	neutral	0,96	10,42	0,54	0,6	neutral	0,15	neutral	0,09	neutral	0,12	neutral	0,27	5	neutral	0,88	deleterious	0,55	neutral	-6	neutral	0,07	medium_impact	0,83	medium_impact	-0,29	low_impact	-2,72	0,33	0,9	13,26	25,03	P	0,58	P	0,2	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12053	12053	C	G	MI.19040	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1294	432	R	G	Cga/Gga	-1,58	0	0	probably_damaging	1	deleterious	0,03	neutral	2,1	deleterious	-3,96	deleterious	-6,33	high_impact	3,86	damaging	0,48	damaging	0,1	deleterious	4,32	24	0,07	0,35	disease	0,74	disease	0,7	disease	0,78	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,79	low_impact	-3,54	medium_impact	-0,64	high_impact	2,69	0,26	0,8	46,84	9,54	N	0,4	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12054	12054	G	C	MI.19041	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1295	432	R	P	cGa/cCa	3,48	0,99	0	probably_damaging	1	deleterious	0,03	neutral	2,09	neutral	-2,21	deleterious	-6,33	high_impact	4,2	damaging	0,47	damaging	0,06	deleterious	4,39	24,1	0,03	0,35	neutral	0,45	disease	0,81	disease	0,84	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,81	low_impact	-3,54	medium_impact	-0,64	high_impact	3,03	0,08	0,8	46,84	9,54	P	0,63	P	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12054	12054	G	A	MI.19042	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1295	432	R	Q	cGa/cAa	3,48	0,99	0	probably_damaging	1	neutral	0,07	neutral	2,14	deleterious	-3,27	deleterious	-3,62	high_impact	3,86	damaging	0,48	damaging	0,05	deleterious	4,64	24,5	0,18	0,45	disease	0,71	disease	0,78	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,75	low_impact	-3,54	medium_impact	-0,43	high_impact	2,69	0,72	0,85	46,84	9,54	P	0,59	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12054	12054	G	T	MI.19043	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1295	432	R	L	cGa/cTa	3,48	0,99	0	probably_damaging	1	neutral	0,21	neutral	2,12	neutral	-0,13	deleterious	-6,33	high_impact	3,86	damaging	0,52	damaging	0,05	deleterious	4,43	24,2	0,08	0,35	disease	0,59	disease	0,84	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	-0,12	high_impact	2,69	0,05	0,8	46,84	9,54	P	0,55	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12056	12056	G	C	MI.19044	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1297	433	E	Q	Gaa/Caa	0,49	0,99	0	probably_damaging	1	deleterious	0,02	neutral	2,07	deleterious	-3,21	deleterious	-2,71	high_impact	4,21	damaging	0,41	neutral	0,53	deleterious	3,52	23,1	0,23	0,45	disease	0,51	disease	0,77	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-3,54	medium_impact	-0,75	high_impact	3,04	0,61	0,8	47,06	9,14	P	0,76	P	0,91	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12056	12056	G	A	MI.19045	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1297	433	E	K	Gaa/Aaa	0,49	0,99	0	probably_damaging	1	deleterious	0,01	neutral	2,12	neutral	-2,69	deleterious	-3,62	high_impact	4,21	damaging	0,41	neutral	0,41	deleterious	4,6	24,4	0,08	0,35	neutral	0,48	disease	0,87	disease	0,79	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,54	medium_impact	-0,92	high_impact	3,04	0,68	0,85	47,06	9,14	P	0,79	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12057	12057	A	G	MI.19046	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1298	433	E	G	gAa/gGa	9,01	1	0	probably_damaging	1	deleterious	0,02	neutral	2,03	neutral	-2,42	deleterious	-6,33	high_impact	3,86	damaging	0,36	neutral	0,6	deleterious	4,17	23,8	0,05	0,35	disease	0,78	disease	0,73	disease	0,8	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,54	medium_impact	-0,75	high_impact	2,69	0,17	0,8	47,06	9,14	P	0,81	P	0,54	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12057	12057	A	T	MI.19047	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1298	433	E	V	gAa/gTa	9,01	1	0	probably_damaging	1	deleterious	0,02	neutral	2,04	neutral	-1,31	deleterious	-6,33	high_impact	4,21	damaging	0,4	neutral	0,53	deleterious	4,12	23,8	0,05	0,35	disease	0,66	disease	0,84	disease	0,79	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,54	medium_impact	-0,75	high_impact	3,04	0,26	0,8	47,06	9,14	P	0,82	P	0,81	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12057	12057	A	C	MI.19048	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1298	433	E	A	gAa/gCa	9,01	1	0	probably_damaging	1	deleterious	0,02	neutral	2,09	neutral	-1,91	deleterious	-5,42	high_impact	4,21	damaging	0,46	neutral	0,54	deleterious	3,6	23,2	0,07	0,35	disease	0,63	disease	0,68	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-3,54	medium_impact	-0,75	high_impact	3,04	0,23	0,8	47,06	9,14	P	0,71	P	0,73	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12058	12058	A	C	MI.19049	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1299	433	E	D	gaA/gaC	8,55	1	0	probably_damaging	1	neutral	0,05	neutral	2,07	neutral	-1,51	deleterious	-2,71	high_impact	3,65	damaging	0,49	neutral	0,53	deleterious	3,78	23,4	0,28	0,45	disease	0,55	disease	0,69	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,74	low_impact	-3,54	medium_impact	-0,52	high_impact	2,49	0,49	0,8	47,06	9,14	P	0,72	P	0,89	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5916	5916	C	A	MI.1905	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	13	5	R	S	Cgt/Agt	-6,12	0	0	probably_damaging	1	neutral	0,09	neutral	-1,19	neutral	-0,64	neutral	-0,68	medium_impact	1,98	damaging	0,47	damaging	0,08	deleterious	4,66	24,5	0,28	0,55	neutral	0,25	disease	0,54	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,73	low_impact	-3,58	medium_impact	-0,37	medium_impact	0,73	0,36	0,9	2,34	6,73	N	0,36	N	0,79	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12058	12058	A	T	MI.19050	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1299	433	E	D	gaA/gaT	8,55	1	0	probably_damaging	1	neutral	0,05	neutral	2,07	neutral	-1,51	deleterious	-2,71	high_impact	3,65	damaging	0,49	neutral	0,53	deleterious	3,91	23,5	0,28	0,45	disease	0,55	disease	0,69	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,74	low_impact	-3,54	medium_impact	-0,52	high_impact	2,49	0,49	0,8	47,06	9,14	P	0,72	P	0,89	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12059	12059	A	T	MI.19051	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1300	434	N	Y	Aac/Tac	0,49	0,98	0	probably_damaging	0,96	neutral	0,99	neutral	2,23	neutral	0,49	deleterious	-3,08	low_impact	1,08	neutral	0,74	neutral	0,69	deleterious	3,68	23,3	0,14	0,4	disease	0,9	neutral	0,39	neutral	0,27	disease	0,67	3	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,79	low_impact	-2,01	medium_impact	1,32	medium_impact	-0,06	0,15	0,8	26,14	20,19	N	0,37	N	0,84	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12059	12059	A	G	MI.19052	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1300	434	N	D	Aac/Gac	0,49	0,98	0	benign	0,05	neutral	0,07	neutral	2,28	neutral	-0,69	deleterious	-3,03	medium_impact	2,48	neutral	0,7	neutral	0,44	deleterious	3,84	23,4	0,43	0,55	disease	0,59	neutral	0,49	disease	0,63	disease	0,66	3	neutral	0,93	deleterious	0,51	neutral	-3	deleterious	0,7	medium_impact	0,48	medium_impact	-0,43	medium_impact	1,33	0,26	0,8	26,14	20,19	N	0,51	P	0,69	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12059	12059	A	C	MI.19053	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1300	434	N	H	Aac/Cac	0,49	0,98	0	probably_damaging	0,96	neutral	1	neutral	2,28	neutral	4,61	neutral	0,76	neutral_impact	-0,06	neutral	0,68	neutral	0,97	deleterious	0,39	6,5	0,3	0,45	disease	0,68	neutral	0,07	neutral	0,2	neutral	0,38	3	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,7	low_impact	-2,01	high_impact	1,88	low_impact	-1,19	0,2	0,8	26,14	20,19	N	0,47	N	0,24	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12060	12060	A	T	MI.19054	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1301	434	N	I	aAc/aTc	1,41	0,98	0	probably_damaging	0,92	neutral	0,22	neutral	2,25	neutral	3,81	deleterious	-5,59	medium_impact	2,48	neutral	0,74	neutral	0,49	deleterious	3,93	23,5	0,16	0,45	disease	0,88	disease	0,67	disease	0,53	disease	0,68	4	neutral	0,94	neutral	0,15	deleterious	1	deleterious	0,82	low_impact	-1,71	medium_impact	-0,11	medium_impact	1,33	0,17	0,8	26,14	20,19	P	0,51	P	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12060	12060	A	C	MI.19055	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1301	434	N	T	aAc/aCc	1,41	0,98	0	possibly_damaging	0,78	neutral	0,1	neutral	2,27	neutral	1,42	deleterious	-3,81	medium_impact	2,48	neutral	0,73	neutral	0,54	deleterious	3,46	23	0,24	0,45	disease	0,73	neutral	0,44	disease	0,53	disease	0,66	3	neutral	0,93	neutral	0,16	NA	0	deleterious	0,76	low_impact	-1,23	medium_impact	-0,33	medium_impact	1,33	0,35	0,8	26,14	20,19	P	0,56	P	0,51	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12060	12060	A	G	MI.19056	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1301	434	N	S	aAc/aGc	1,41	0,98	0	possibly_damaging	0,52	neutral	0,15	neutral	2,31	neutral	1,12	deleterious	-2,85	medium_impact	2,28	neutral	0,78	neutral	0,77	deleterious	3,06	22,4	0,44	0,55	neutral	0,5	neutral	0,39	neutral	0,42	neutral	0,36	3	neutral	0,84	neutral	0,32	NA	0	deleterious	0,72	medium_impact	-0,75	medium_impact	-0,22	medium_impact	1,13	0,29	0,8	26,14	20,19	P	0,54	P	0,41	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12061	12061	C	A	MI.19057	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1302	434	N	K	aaC/aaA	4,63	0,99	0	possibly_damaging	0,73	neutral	0,12	neutral	2,33	neutral	0,4	deleterious	-3,44	medium_impact	2,83	neutral	0,73	neutral	0,38	deleterious	4,51	24,3	0,31	0,45	disease	0,54	disease	0,57	disease	0,64	disease	0,7	4	neutral	0,91	neutral	0,2	NA	0	deleterious	0,75	low_impact	-1,12	medium_impact	-0,28	medium_impact	1,67	0,21	0,8	26,14	20,19	P	0,61	P	0,74	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12061	12061	C	G	MI.19058	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1302	434	N	K	aaC/aaG	4,63	0,99	0	possibly_damaging	0,73	neutral	0,12	neutral	2,33	neutral	0,4	deleterious	-3,44	medium_impact	2,83	neutral	0,73	neutral	0,38	deleterious	4,09	23,7	0,31	0,45	disease	0,54	disease	0,57	disease	0,64	disease	0,7	4	neutral	0,91	neutral	0,2	NA	0	deleterious	0,75	low_impact	-1,12	medium_impact	-0,28	medium_impact	1,67	0,21	0,8	26,14	20,19	P	0,61	P	0,74	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12062	12062	A	G	MI.19059	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1303	435	T	A	Acc/Gcc	-5,5	0	0	benign	0,02	neutral	0,06	neutral	2,34	neutral	1,13	neutral	-0,74	low_impact	1,58	neutral	0,8	neutral	0,99	deleterious	0,18	4,43	0,29	0,45	neutral	0,39	neutral	0,21	neutral	0,37	neutral	0,37	3	neutral	0,94	deleterious	0,52	neutral	-6	neutral	0,12	medium_impact	0,87	medium_impact	-0,47	medium_impact	0,44	0,35	0,8	29,63	19,19	N	0,45	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5916	5916	C	G	MI.1906	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	13	5	R	G	Cgt/Ggt	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	-1,19	neutral	-1,03	neutral	-0,84	medium_impact	2,38	damaging	0,5	damaging	0,08	deleterious	4,13	23,8	0,34	0,55	neutral	0,49	disease	0,53	disease	0,76	disease	0,74	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	medium_impact	1,1	0,43	0,9	2,34	6,73	N	0,35	N	0,91	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12062	12062	A	T	MI.19060	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1303	435	T	S	Acc/Tcc	-5,5	0	0	benign	0,03	deleterious	0,04	neutral	2,3	neutral	0,41	neutral	-1,09	low_impact	1,93	neutral	0,81	neutral	0,98	deleterious	0,27	5,39	0,35	0,5	disease	0,54	neutral	0,29	neutral	0,31	neutral	0,46	1	neutral	0,96	deleterious	0,51	neutral	-2	neutral	0,15	medium_impact	0,7	medium_impact	-0,57	medium_impact	0,78	0,57	0,8	29,63	19,19	N	0,46	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12062	12062	A	C	MI.19061	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1303	435	T	P	Acc/Ccc	-5,5	0	0	benign	0,16	deleterious	0,01	neutral	2,24	neutral	-2,56	deleterious	-2,56	medium_impact	2,62	neutral	0,64	neutral	0,39	neutral	1,61	13,89	0,03	0,35	disease	0,82	disease	0,7	disease	0,61	disease	0,76	5	deleterious	0,99	neutral	0,43	deleterious	1	neutral	0,33	medium_impact	-0,04	medium_impact	-0,92	medium_impact	1,47	0,26	0,8	29,63	19,19	N	0,29	N	0,7	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12063	12063	C	G	MI.19062	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1304	435	T	S	aCc/aGc	0,03	0	0	benign	0,03	deleterious	0,04	neutral	2,3	neutral	0,41	neutral	-1,09	low_impact	1,93	neutral	0,81	neutral	0,98	deleterious	0,66	8,57	0,35	0,5	disease	0,54	neutral	0,29	neutral	0,31	neutral	0,46	1	neutral	0,96	deleterious	0,51	neutral	-2	neutral	0,15	medium_impact	0,7	medium_impact	-0,57	medium_impact	0,78	0,57	0,8	29,63	19,19	N	0,45	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12063	12063	C	T	MI.19063	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1304	435	T	I	aCc/aTc	0,03	0	0	benign	0	neutral	0,09	neutral	2,34	neutral	0,78	neutral	-0,33	low_impact	1,27	neutral	0,75	neutral	0,96	neutral	1	10,68	0,1	0,4	disease	0,64	neutral	0,47	neutral	0,2	disease	0,61	2	neutral	0,91	deleterious	0,55	neutral	-6	neutral	0,15	high_impact	2,1	medium_impact	-0,36	medium_impact	0,13	0,55	0,8	29,63	19,19	N	0,5	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12063	12063	C	A	MI.19064	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1304	435	T	N	aCc/aAc	0,03	0	0	benign	0,11	neutral	0,06	neutral	2,25	neutral	-2,25	neutral	-2,35	medium_impact	2,27	neutral	0,7	neutral	0,58	deleterious	1,88	15,46	0,25	0,45	disease	0,79	neutral	0,49	neutral	0,47	disease	0,59	2	neutral	0,93	deleterious	0,48	neutral	-3	neutral	0,23	medium_impact	0,14	medium_impact	-0,47	medium_impact	1,12	0,56	0,8	29,63	19,19	N	0,4	N	0,36	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12065	12065	C	G	MI.19065	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1306	436	L	V	Ctc/Gtc	-11,02	0	0	probably_damaging	1	neutral	0,14	neutral	2,21	deleterious	-3,02	neutral	-2,48	medium_impact	2,96	neutral	0,67	neutral	0,56	deleterious	3,57	23,1	0,29	0,45	disease	0,86	neutral	0,46	neutral	0,47	disease	0,63	3	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,24	medium_impact	1,8	0,54	0,8	44,23	8,24	N	0,4	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12065	12065	C	A	MI.19066	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1306	436	L	I	Ctc/Atc	-11,02	0	0	probably_damaging	1	neutral	0,12	neutral	2,21	neutral	-1,8	neutral	-1,59	medium_impact	2,17	neutral	0,76	neutral	0,75	deleterious	4,16	23,8	0,33	0,5	disease	0,77	neutral	0,46	neutral	0,27	disease	0,61	2	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,74	low_impact	-3,54	medium_impact	-0,28	medium_impact	1,02	0,52	0,8	44,23	8,24	N	0,42	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12065	12065	C	T	MI.19067	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1306	436	L	F	Ctc/Ttc	-11,02	0	0	probably_damaging	1	neutral	0,07	neutral	2,09	neutral	-1,44	deleterious	-3,5	high_impact	3,76	neutral	0,66	neutral	0,45	deleterious	4,1	23,7	0,16	0,45	disease	0,94	disease	0,59	disease	0,67	disease	0,8	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,8	low_impact	-3,54	medium_impact	-0,43	high_impact	2,59	0,67	0,85	44,23	8,24	N	0,42	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12066	12066	T	G	MI.19068	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1307	436	L	R	cTc/cGc	-0,2	0	0	probably_damaging	1	deleterious	0,02	neutral	2,06	deleterious	-5,14	deleterious	-5,35	high_impact	4,11	neutral	0,65	neutral	0,34	deleterious	4,35	24,1	0,01	0,35	neutral	0,38	disease	0,85	disease	0,79	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,54	medium_impact	-0,75	high_impact	2,94	0,09	0,8	44,23	8,24	N	0,42	N	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12066	12066	T	C	MI.19069	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1307	436	L	P	cTc/cCc	-0,2	0	0	probably_damaging	1	deleterious	0,01	neutral	2,08	deleterious	-5,78	deleterious	-6,19	high_impact	3,76	damaging	0,58	neutral	0,34	deleterious	4,06	23,7	0,02	0,35	disease	0,9	disease	0,77	disease	0,78	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,54	medium_impact	-0,92	high_impact	2,59	0,08	0,8	44,23	8,24	N	0,39	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5916	5916	C	T	MI.1907	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	13	5	R	C	Cgt/Tgt	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	-1,2	deleterious	-5,45	neutral	-0,98	high_impact	4,04	damaging	0,48	damaging	0,07	deleterious	4,92	25	0,34	0,55	disease	0,8	disease	0,66	disease	0,79	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,63	0,75	0,9	2,34	6,73	N	0,4	N	1	disease_causing	0,66	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12066	12066	T	A	MI.19070	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1307	436	L	H	cTc/cAc	-0,2	0	0	probably_damaging	1	deleterious	0,01	neutral	2,04	deleterious	-5,72	deleterious	-6,2	high_impact	4,11	neutral	0,67	neutral	0,33	deleterious	4,27	23,9	0,03	0,35	disease	0,84	disease	0,78	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,54	medium_impact	-0,92	high_impact	2,94	0,12	0,8	44,23	8,24	N	0,36	N	0,96	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12068	12068	A	T	MI.19071	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1309	437	M	L	Atg/Ttg	-10,1	0	0	probably_damaging	0,94	neutral	0,95	neutral	2,44	neutral	1,41	neutral	-2,18	low_impact	1,47	neutral	0,69	damaging	0,27	deleterious	2,05	16,56	0,22	0,45	disease	0,61	neutral	0,38	neutral	0,3	disease	0,62	2	neutral	0,93	deleterious	0,51	neutral	-2	neutral	0,43	low_impact	-1,84	medium_impact	0,92	medium_impact	0,33	0,34	0,8	47,28	8,68	N	0,24	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12068	12068	A	C	MI.19072	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1309	437	M	L	Atg/Ctg	-10,1	0	0	probably_damaging	0,94	neutral	0,95	neutral	2,44	neutral	1,41	neutral	-2,18	low_impact	1,47	neutral	0,69	damaging	0,27	deleterious	2,04	16,48	0,22	0,45	disease	0,61	neutral	0,38	neutral	0,3	disease	0,62	2	neutral	0,93	deleterious	0,51	neutral	-2	neutral	0,43	low_impact	-1,84	medium_impact	0,92	medium_impact	0,33	0,34	0,8	47,28	8,68	N	0,24	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12068	12068	A	G	MI.19073	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1309	437	M	V	Atg/Gtg	-10,1	0	0	probably_damaging	0,97	neutral	0,08	neutral	2,34	neutral	-0,59	deleterious	-3,08	medium_impact	3,37	neutral	0,76	neutral	0,28	deleterious	2,54	19,74	0,21	0,45	disease	0,7	disease	0,68	neutral	0,43	disease	0,51	0	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,53	low_impact	-2,14	medium_impact	-0,39	high_impact	2,21	0,38	0,8	47,28	8,68	N	0,38	N	0,96	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12069	12069	T	A	MI.19074	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1310	437	M	K	aTg/aAg	3,48	0,99	0	probably_damaging	0,98	deleterious	0	neutral	2,21	neutral	-1,23	deleterious	-5,18	high_impact	3,91	neutral	0,62	damaging	0,12	deleterious	4,14	23,8	0,02	0,35	disease	0,6	disease	0,85	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,71	low_impact	-2,31	low_impact	-1,48	high_impact	2,74	0,22	0,8	47,28	8,68	P	0,54	P	1	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12069	12069	T	C	MI.19075	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1310	437	M	T	aTg/aCg	3,48	0,99	0	probably_damaging	0,98	deleterious	0,03	neutral	2,25	neutral	-1,05	deleterious	-5	high_impact	3,56	neutral	0,64	damaging	0,14	deleterious	3	22,2	0,06	0,35	disease	0,55	disease	0,73	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,71	low_impact	-2,31	medium_impact	-0,64	high_impact	2,4	0,12	0,8	47,28	8,68	P	0,5	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12070	12070	G	T	MI.19076	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1311	437	M	I	atG/atT	5,55	1	0,01	probably_damaging	0,97	neutral	0,41	neutral	2,34	neutral	0,2	deleterious	-2,97	medium_impact	2,08	neutral	0,75	neutral	0,79	deleterious	2,26	17,91	0,21	0,45	disease	0,71	disease	0,55	neutral	0,33	disease	0,51	0	neutral	0,97	neutral	0,22	deleterious	1	deleterious	0,6	low_impact	-2,14	medium_impact	0,11	medium_impact	0,93	0,41	0,8	47,28	8,68	P	0,61	P	0,97	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12070	12070	G	C	MI.19077	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1311	437	M	I	atG/atC	5,55	1	0,01	probably_damaging	0,97	neutral	0,41	neutral	2,34	neutral	0,2	deleterious	-2,97	medium_impact	2,08	neutral	0,75	neutral	0,79	deleterious	2,12	17,01	0,21	0,45	disease	0,71	disease	0,55	neutral	0,33	disease	0,51	0	neutral	0,97	neutral	0,22	deleterious	1	deleterious	0,6	low_impact	-2,14	medium_impact	0,11	medium_impact	0,93	0,41	0,8	47,28	8,68	P	0,6	P	0,97	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12071	12071	T	A	MI.19078	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1312	438	F	I	Ttc/Atc	-0,2	0	0	benign	0,01	neutral	0,34	neutral	2,34	neutral	-0,53	neutral	0,51	low_impact	0,91	neutral	0,75	neutral	0,96	neutral	1,21	11,81	0,14	0,4	disease	0,68	neutral	0,44	neutral	0,18	disease	0,62	2	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,14	medium_impact	1,16	medium_impact	0,04	medium_impact	-0,23	0,62	0,8	28,32	26,44	N	0,51	P	0,28	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12071	12071	T	G	MI.19079	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1312	438	F	V	Ttc/Gtc	-0,2	0	0	benign	0,05	neutral	0,23	neutral	2,33	neutral	-0,79	neutral	0,85	low_impact	1,09	neutral	0,74	neutral	0,93	deleterious	0,67	8,65	0,1	0,4	disease	0,55	neutral	0,49	neutral	0,2	disease	0,5	0	neutral	0,75	deleterious	0,59	neutral	-6	neutral	0,13	medium_impact	0,48	medium_impact	-0,09	medium_impact	-0,05	0,51	0,8	28,32	26,44	N	0,5	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5917	5917	G	C	MI.1908	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	14	5	R	P	cGt/cCt	2,9	0,98	0	probably_damaging	1	deleterious	0	neutral	-1,2	neutral	-2,47	neutral	-0,81	medium_impact	3,34	damaging	0,46	damaging	0,08	deleterious	4,28	24	0,18	0,55	disease	0,57	disease	0,69	disease	0,78	disease	0,76	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	medium_impact	1,99	0,28	0,9	2,34	6,73	P	0,55	P	0,99	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12071	12071	T	C	MI.19080	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1312	438	F	L	Ttc/Ctc	-0,2	0	0	benign	0	neutral	0,69	neutral	2,38	neutral	1,54	neutral	0,65	neutral_impact	-0,3	neutral	0,79	neutral	0,96	deleterious	0,61	8,22	0,16	0,45	disease	0,62	neutral	0,38	neutral	0,16	disease	0,61	2	neutral	0,3	deleterious	0,85	neutral	-6	neutral	0,13	high_impact	2,1	medium_impact	0,4	low_impact	-1,42	0,66	0,8	28,32	26,44	N	0,41	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12072	12072	T	C	MI.19081	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1313	438	F	S	tTc/tCc	-3,65	0	0	benign	0,01	neutral	0,22	neutral	2,24	neutral	0,95	neutral	1,6	low_impact	0,86	neutral	0,79	neutral	0,98	deleterious	0,57	7,93	0,05	0,35	neutral	0,39	neutral	0,42	neutral	0,27	neutral	0,47	1	neutral	0,78	deleterious	0,61	neutral	-6	neutral	0,21	medium_impact	1,16	medium_impact	-0,11	medium_impact	-0,28	0,32	0,8	28,32	26,44	N	0,39	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12072	12072	T	A	MI.19082	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1313	438	F	Y	tTc/tAc	-3,65	0	0	benign	0,27	neutral	0,11	neutral	2,21	neutral	-2,27	neutral	-0,28	low_impact	1,92	neutral	0,8	neutral	0,85	neutral	0,96	10,44	0,16	0,45	disease	0,69	neutral	0,41	neutral	0,34	disease	0,63	3	neutral	0,87	neutral	0,42	neutral	-6	neutral	0,21	medium_impact	-0,31	medium_impact	-0,31	medium_impact	0,77	0,68	0,85	28,32	26,44	N	0,46	N	0,32	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12072	12072	T	G	MI.19083	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1313	438	F	C	tTc/tGc	-3,65	0	0	possibly_damaging	0,75	deleterious	0,02	neutral	2,19	deleterious	-3,29	neutral	0,2	medium_impact	2,27	neutral	0,79	neutral	0,48	deleterious	2,54	19,73	0,05	0,35	disease	0,79	disease	0,67	neutral	0,27	disease	0,54	1	deleterious	0,98	neutral	0,14	deleterious	4	deleterious	0,49	low_impact	-1,17	medium_impact	-0,75	medium_impact	1,12	0,19	0,8	28,32	26,44	N	0,41	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12073	12073	C	A	MI.19084	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1314	438	F	L	ttC/ttA	-0,43	0	0	benign	0	neutral	0,69	neutral	2,38	neutral	1,54	neutral	0,65	neutral_impact	-0,3	neutral	0,79	neutral	0,96	neutral	1,22	11,88	0,16	0,45	disease	0,62	neutral	0,38	neutral	0,16	disease	0,61	2	neutral	0,3	deleterious	0,85	neutral	-6	neutral	0,13	high_impact	2,1	medium_impact	0,4	low_impact	-1,42	0,66	0,8	28,32	26,44	N	0,4	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12073	12073	C	G	MI.19085	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1314	438	F	L	ttC/ttG	-0,43	0	0	benign	0	neutral	0,69	neutral	2,38	neutral	1,54	neutral	0,65	neutral_impact	-0,3	neutral	0,79	neutral	0,96	neutral	0,89	10,01	0,16	0,45	disease	0,62	neutral	0,38	neutral	0,16	disease	0,61	2	neutral	0,3	deleterious	0,85	neutral	-6	neutral	0,13	high_impact	2,1	medium_impact	0,4	low_impact	-1,42	0,66	0,8	28,32	26,44	N	0,4	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12074	12074	A	G	MI.19086	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1315	439	M	V	Ata/Gta	-13,78	0	0	benign	0,23	deleterious	0,01	neutral	2,43	neutral	0,99	neutral	-1,44	medium_impact	2,84	neutral	0,72	neutral	0,7	deleterious	2,59	20,1	0,21	0,45	neutral	0,42	disease	0,59	disease	0,51	disease	0,55	1	deleterious	0,99	neutral	0,39	deleterious	1	deleterious	0,48	medium_impact	-0,23	medium_impact	-0,92	medium_impact	1,68	0,34	0,8	21,79	25,23	N	0,43	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12074	12074	A	C	MI.19087	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1315	439	M	L	Ata/Cta	-13,78	0	0	benign	0,01	neutral	1	neutral	2,54	neutral	4,86	neutral	0,8	neutral_impact	-0,27	neutral	0,77	neutral	1	deleterious	0,39	6,5	0,19	0,45	disease	0,57	neutral	0,2	neutral	0,24	neutral	0,45	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,37	medium_impact	1,16	high_impact	1,88	low_impact	-1,39	0,28	0,8	21,79	25,23	N	0,34	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12074	12074	A	T	MI.19088	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1315	439	M	L	Ata/Tta	-13,78	0	0	benign	0,01	neutral	1	neutral	2,54	neutral	4,86	neutral	0,8	neutral_impact	-0,27	neutral	0,77	neutral	1	deleterious	0,45	7,06	0,19	0,45	disease	0,57	neutral	0,2	neutral	0,24	neutral	0,45	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,37	medium_impact	1,16	high_impact	1,88	low_impact	-1,39	0,28	0,8	21,79	25,23	N	0,34	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12075	12075	T	A	MI.19089	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1316	439	M	K	aTa/aAa	-1,12	0	0	possibly_damaging	0,69	deleterious	0	neutral	2,26	neutral	2,6	deleterious	-4	medium_impact	3,19	neutral	0,66	neutral	0,5	deleterious	4,01	23,6	0,03	0,35	disease	0,88	disease	0,79	disease	0,71	disease	0,8	6	deleterious	1	neutral	0,16	deleterious	4	deleterious	0,78	low_impact	-1,04	low_impact	-1,48	high_impact	2,03	0,23	0,8	21,79	25,23	N	0,35	N	0,85	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5917	5917	G	T	MI.1909	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	14	5	R	L	cGt/cTt	2,9	0,98	0	probably_damaging	0,99	deleterious	0	neutral	-1,19	deleterious	-3,4	neutral	-0,84	medium_impact	3,13	damaging	0,47	damaging	0,07	deleterious	4,31	24	0,4	0,55	neutral	0,47	disease	0,68	disease	0,76	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	medium_impact	1,79	0,25	0,9	2,34	6,73	P	0,58	P	0,98	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12075	12075	T	C	MI.19090	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1316	439	M	T	aTa/aCa	-1,12	0	0	possibly_damaging	0,48	deleterious	0,01	neutral	2,31	neutral	1,83	deleterious	-3,27	medium_impact	2,84	neutral	0,69	neutral	0,58	deleterious	3,01	22,3	0,11	0,4	disease	0,72	disease	0,56	disease	0,63	disease	0,69	4	deleterious	0,99	neutral	0,27	deleterious	4	deleterious	0,7	medium_impact	-0,69	medium_impact	-0,92	medium_impact	1,68	0,14	0,8	21,79	25,23	N	0,36	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12076	12076	A	C	MI.19091	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1317	439	M	I	atA/atC	7,4	0,95	0	benign	0,23	deleterious	0,03	neutral	2,37	neutral	0,4	neutral	-0,74	medium_impact	2,84	neutral	0,71	neutral	0,68	deleterious	3,36	22,9	0,25	0,45	neutral	0,43	disease	0,63	neutral	0,47	disease	0,53	1	neutral	0,97	neutral	0,4	deleterious	1	deleterious	0,58	medium_impact	-0,23	medium_impact	-0,64	medium_impact	1,68	0,4	0,8	21,79	25,23	P	0,6	P	0,27	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12076	12076	A	T	MI.19092	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1317	439	M	I	atA/atT	7,4	0,95	0	benign	0,23	deleterious	0,03	neutral	2,37	neutral	0,4	neutral	-0,74	medium_impact	2,84	neutral	0,71	neutral	0,68	deleterious	3,4	23	0,25	0,45	neutral	0,43	disease	0,63	neutral	0,47	disease	0,53	1	neutral	0,97	neutral	0,4	deleterious	1	deleterious	0,58	medium_impact	-0,23	medium_impact	-0,64	medium_impact	1,68	0,4	0,8	21,79	25,23	P	0,6	P	0,27	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12077	12077	C	T	MI.19093	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1318	440	H	Y	Cac/Tac	-14,94	0	0	probably_damaging	1	deleterious	0,04	neutral	2,21	neutral	-2,31	deleterious	-5,43	high_impact	4,2	damaging	0,51	damaging	0,05	deleterious	3,82	23,4	0,16	0,45	disease	0,88	disease	0,69	disease	0,77	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,78	low_impact	-3,54	medium_impact	-0,57	high_impact	3,03	0,16	0,8	47,49	9,19	N	0,38	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12077	12077	C	G	MI.19094	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1318	440	H	D	Cac/Gac	-14,94	0	0	probably_damaging	1	deleterious	0	neutral	2,21	deleterious	-3,46	deleterious	-8,14	high_impact	4,2	damaging	0,51	damaging	0,06	deleterious	3,98	23,6	0,06	0,35	disease	0,89	disease	0,72	disease	0,83	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,27	0,8	47,49	9,19	N	0,41	N	0,97	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12077	12077	C	A	MI.19095	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1318	440	H	N	Cac/Aac	-14,94	0	0	probably_damaging	1	neutral	0,1	neutral	2,22	neutral	-2,07	deleterious	-6,33	high_impact	4,2	damaging	0,5	damaging	0,07	deleterious	4	23,6	0,21	0,45	disease	0,83	disease	0,65	disease	0,76	disease	0,75	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,75	low_impact	-3,54	medium_impact	-0,33	high_impact	3,03	0,37	0,8	47,49	9,19	N	0,37	N	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12078	12078	A	T	MI.19096	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1319	440	H	L	cAc/cTc	5,32	1	0	probably_damaging	1	neutral	0,11	neutral	2,41	neutral	-1,8	deleterious	-9,95	high_impact	4,2	damaging	0,53	damaging	0,05	deleterious	3,82	23,4	0,05	0,35	disease	0,72	disease	0,8	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,77	low_impact	-3,54	medium_impact	-0,31	high_impact	3,03	0,14	0,8	47,49	9,19	P	0,64	P	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12078	12078	A	G	MI.19097	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1319	440	H	R	cAc/cGc	5,32	1	0	probably_damaging	1	deleterious	0	neutral	2,22	neutral	0,1	deleterious	-7,24	high_impact	4,2	damaging	0,59	damaging	0,06	deleterious	2,99	22,2	0,09	0,35	disease	0,85	disease	0,75	disease	0,79	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,26	0,8	47,49	9,19	P	0,62	P	0,97	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12078	12078	A	C	MI.19098	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1319	440	H	P	cAc/cCc	5,32	1	0	probably_damaging	1	deleterious	0	neutral	2,22	neutral	-2,09	deleterious	-9,05	high_impact	3,65	damaging	0,52	damaging	0,08	deleterious	3,26	22,8	0,05	0,35	disease	0,86	disease	0,77	disease	0,8	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,54	low_impact	-1,48	high_impact	2,49	0,19	0,8	47,49	9,19	P	0,62	P	0,95	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12079	12079	C	G	MI.19099	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1320	440	H	Q	caC/caG	8,55	1	0	probably_damaging	1	deleterious	0	neutral	2,22	deleterious	-3,1	deleterious	-7,24	high_impact	4,2	damaging	0,54	damaging	0,06	deleterious	3,72	23,3	0,11	0,4	disease	0,85	disease	0,69	disease	0,76	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,31	0,8	47,49	9,19	P	0,62	P	0,93	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8616	8616	G	C	MI.191	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	90	30	L	F	ttG/ttC	7,53	0,96	0,02	probably_damaging	1	neutral	0,39	neutral	4,31	neutral	-0,71	deleterious	-3,18	low_impact	1,63	neutral	0,91	neutral	0,87	deleterious	2,21	17,59	0,41	0,65	disease	0,66	neutral	0,4	neutral	0,15	disease	0,62	2	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,18	medium_impact	0,3	0,59	0,9	17,7	14,1	P	0,54	P	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5917	5917	G	A	MI.1910	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	14	5	R	H	cGt/cAt	2,9	0,98	0	probably_damaging	1	deleterious	0	neutral	-1,2	deleterious	-3,15	neutral	-0,6	medium_impact	3,23	damaging	0,47	damaging	0,07	deleterious	4,3	24	0,47	0,55	disease	0,53	disease	0,51	disease	0,75	disease	0,75	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	medium_impact	1,88	0,84	0,9	2,34	6,73	P	0,58	P	0,98	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12079	12079	C	A	MI.19100	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1320	440	H	Q	caC/caA	8,55	1	0	probably_damaging	1	deleterious	0	neutral	2,22	deleterious	-3,1	deleterious	-7,24	high_impact	4,2	damaging	0,54	damaging	0,06	deleterious	4,05	23,7	0,11	0,4	disease	0,85	disease	0,69	disease	0,76	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,31	0,8	47,49	9,19	P	0,63	P	0,93	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12080	12080	C	G	MI.19101	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1321	441	L	V	Cta/Gta	-3,19	0	0	benign	0,14	neutral	0,23	neutral	2,17	neutral	-2,66	neutral	-1,18	medium_impact	2,47	neutral	0,84	neutral	0,86	deleterious	3,47	23	0,33	0,5	disease	0,58	neutral	0,37	neutral	0,14	disease	0,61	2	neutral	0,73	deleterious	0,55	neutral	-3	deleterious	0,68	medium_impact	0,02	medium_impact	-0,09	medium_impact	1,32	0,47	0,8	7,84	16,1	N	0,5	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12080	12080	C	A	MI.19102	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1321	441	L	M	Cta/Ata	-3,19	0	0	benign	0,07	neutral	0,21	neutral	2,07	neutral	-2,67	neutral	-0,69	low_impact	1,31	neutral	0,8	neutral	0,96	deleterious	2,78	21,3	0,28	0,45	disease	0,55	neutral	0,22	neutral	0,12	neutral	0,49	0	neutral	0,77	deleterious	0,57	neutral	-6	deleterious	0,68	medium_impact	0,34	medium_impact	-0,12	medium_impact	0,17	0,37	0,8	7,84	16,1	N	0,5	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12081	12081	T	A	MI.19103	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1322	441	L	Q	cTa/cAa	-0,66	0	0	possibly_damaging	0,77	deleterious	0,03	neutral	2,02	neutral	-1,89	deleterious	-4,21	high_impact	3,71	neutral	0,66	neutral	0,53	deleterious	4,26	23,9	0,03	0,35	disease	0,86	disease	0,69	neutral	0,44	disease	0,62	2	neutral	0,98	neutral	0,13	deleterious	5	deleterious	0,78	low_impact	-1,21	medium_impact	-0,64	high_impact	2,54	0,12	0,8	7,84	16,1	N	0,46	N	0,83	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12081	12081	T	C	MI.19104	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1322	441	L	P	cTa/cCa	-0,66	0	0	possibly_damaging	0,87	deleterious	0,02	neutral	2,01	deleterious	-5,33	deleterious	-4,96	high_impact	3,71	neutral	0,62	neutral	0,39	deleterious	4,07	23,7	0,02	0,35	disease	0,88	disease	0,81	disease	0,6	disease	0,77	5	deleterious	0,99	neutral	0,08	deleterious	5	deleterious	0,85	low_impact	-1,49	medium_impact	-0,75	high_impact	2,54	0,17	0,8	7,84	16,1	N	0,37	N	0,93	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12081	12081	T	G	MI.19105	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1322	441	L	R	cTa/cGa	-0,66	0	0	possibly_damaging	0,77	neutral	0,06	neutral	2,02	deleterious	-4,63	deleterious	-4,38	high_impact	3,71	neutral	0,62	neutral	0,45	deleterious	4,37	24,1	0,02	0,35	disease	0,84	disease	0,81	disease	0,6	disease	0,77	5	neutral	0,96	neutral	0,15	deleterious	1	deleterious	0,83	low_impact	-1,21	medium_impact	-0,47	high_impact	2,54	0,08	0,8	7,84	16,1	N	0,42	N	0,87	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12083	12083	T	A	MI.19106	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1324	442	S	T	Tcc/Acc	-9,87	0	0,03	benign	0	neutral	0,16	neutral	2,3	neutral	2,18	neutral	0,72	neutral_impact	-0,44	neutral	0,78	neutral	0,99	deleterious	0,77	9,3	0,26	0,45	disease	0,83	neutral	0,11	neutral	0,09	neutral	0,43	1	neutral	0,84	deleterious	0,58	neutral	-6	neutral	0,19	high_impact	2,1	medium_impact	-0,2	low_impact	-1,56	0,41	0,8	26,58	30,72	N	0,52	P	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12083	12083	T	C	MI.19107	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1324	442	S	P	Tcc/Ccc	-9,87	0	0,03	benign	0,3	deleterious	0,01	neutral	2,23	neutral	1,92	neutral	-1,11	low_impact	1,59	neutral	0,6	neutral	0,39	deleterious	2,26	17,9	0,09	0,35	disease	0,97	disease	0,62	neutral	0,44	disease	0,83	7	deleterious	0,99	neutral	0,36	neutral	-2	deleterious	0,47	medium_impact	-0,37	medium_impact	-0,92	medium_impact	0,45	0,28	0,8	26,58	30,72	N	0,35	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12083	12083	T	G	MI.19108	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1324	442	S	A	Tcc/Gcc	-9,87	0	0,03	benign	0	neutral	0,14	neutral	2,38	neutral	1,37	neutral	0,7	neutral_impact	-1	neutral	0,75	neutral	0,99	deleterious	0,56	7,89	0,31	0,45	disease	0,84	neutral	0,09	neutral	0,11	neutral	0,41	2	neutral	0,86	deleterious	0,57	neutral	-6	neutral	0,18	high_impact	2,1	medium_impact	-0,24	low_impact	-2,12	0,29	0,8	26,58	30,72	N	0,55	P	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12084	12084	C	G	MI.19109	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1325	442	S	C	tCc/tGc	-7,57	0	0,01	possibly_damaging	0,57	deleterious	0,03	neutral	2,22	neutral	-2,02	neutral	0,44	low_impact	1,04	neutral	0,69	neutral	0,42	deleterious	2	16,21	0,1	0,4	disease	0,97	neutral	0,34	neutral	0,36	disease	0,66	3	neutral	0,97	neutral	0,23	deleterious	1	deleterious	0,49	medium_impact	-0,83	medium_impact	-0,64	medium_impact	-0,1	0,23	0,8	26,58	30,72	N	0,43	N	0,37	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5919	5919	T	C	MI.1911	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	16	6	W	R	Tga/Cga	-4,96	0	0	probably_damaging	1	deleterious	0	deleterious	-1,86	deleterious	-6	neutral	-1,89	high_impact	3,68	neutral	0,63	damaging	0,09	deleterious	3,57	23,1	0,34	0,55	disease	0,91	disease	0,82	disease	0,86	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,3	0,22	0,9	3,12	6,72	N	0,35	N	0,94	polymorphism	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12084	12084	C	A	MI.19110	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1325	442	S	Y	tCc/tAc	-7,57	0	0,01	benign	0,14	neutral	0,08	neutral	2,24	neutral	-1,1	neutral	0,39	neutral_impact	0,78	neutral	0,77	neutral	0,61	deleterious	2,4	18,79	0,09	0,4	disease	0,95	neutral	0,32	neutral	0,43	disease	0,64	3	neutral	0,91	deleterious	0,47	neutral	-6	neutral	0,25	medium_impact	0,02	medium_impact	-0,39	medium_impact	-0,35	0,23	0,8	26,58	30,72	N	0,41	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12084	12084	C	T	MI.19111	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1325	442	S	F	tCc/tTc	-7,57	0	0,01	benign	0	neutral	0,78	neutral	2,29	neutral	1,42	neutral	1,21	neutral_impact	-0,2	neutral	0,83	neutral	0,9	neutral	1,28	12,15	0,09	0,35	disease	0,93	neutral	0,26	neutral	0,16	disease	0,58	2	neutral	0,21	deleterious	0,89	neutral	-6	neutral	0,22	high_impact	2,1	medium_impact	0,51	low_impact	-1,32	0,16	0,8	26,58	30,72	N	0,36	N	0,35	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12086	12086	C	T	MI.19112	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1327	443	P	S	Ccc/Tcc	-5,73	0	0	probably_damaging	1	deleterious	0,01	neutral	2,14	deleterious	-3,41	deleterious	-7,22	high_impact	4,2	damaging	0,57	neutral	0,53	deleterious	4,07	23,7	0,17	0,45	disease	0,6	disease	0,67	disease	0,6	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-3,54	medium_impact	-0,92	high_impact	3,03	0,11	0,8	47,06	9,61	N	0,4	N	0,68	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12086	12086	C	G	MI.19113	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1327	443	P	A	Ccc/Gcc	-5,73	0	0	probably_damaging	1	deleterious	0,04	neutral	2,18	neutral	-2,82	deleterious	-7,22	high_impact	3,86	neutral	0,62	neutral	0,51	deleterious	3,25	22,8	0,15	0,4	neutral	0,4	neutral	0,5	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,71	low_impact	-3,54	medium_impact	-0,57	high_impact	2,69	0,5	0,8	47,06	9,61	N	0,45	N	0,74	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12086	12086	C	A	MI.19114	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1327	443	P	T	Ccc/Acc	-5,73	0	0	probably_damaging	1	deleterious	0	neutral	2,15	neutral	-1,85	deleterious	-7,22	high_impact	3,86	damaging	0,59	neutral	0,47	deleterious	3,87	23,5	0,14	0,4	disease	0,73	disease	0,68	disease	0,7	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,54	low_impact	-1,48	high_impact	2,69	0,43	0,8	47,06	9,61	N	0,38	N	0,88	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12087	12087	C	A	MI.19115	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1328	443	P	H	cCc/cAc	5,32	0,99	0	probably_damaging	1	deleterious	0,02	neutral	2,09	neutral	-1,63	deleterious	-8,13	high_impact	4,2	neutral	0,61	neutral	0,39	deleterious	4,19	23,8	0,08	0,35	disease	0,87	disease	0,79	disease	0,8	disease	0,85	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,54	medium_impact	-0,75	high_impact	3,03	0,2	0,8	47,06	9,61	P	0,67	P	0,7	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12087	12087	C	T	MI.19116	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1328	443	P	L	cCc/cTc	5,32	0,99	0	probably_damaging	1	deleterious	0,04	neutral	2,24	neutral	-2,31	deleterious	-9,03	high_impact	3,86	damaging	0,57	neutral	0,45	deleterious	4,57	24,4	0,15	0,4	disease	0,53	disease	0,77	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,75	low_impact	-3,54	medium_impact	-0,57	high_impact	2,69	0,55	0,8	47,06	9,61	P	0,62	P	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12087	12087	C	G	MI.19117	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1328	443	P	R	cCc/cGc	5,32	0,99	0	probably_damaging	1	deleterious	0	neutral	2,11	deleterious	-4,24	deleterious	-8,13	high_impact	4,2	neutral	0,66	neutral	0,44	deleterious	3,76	23,3	0,05	0,35	disease	0,79	disease	0,82	disease	0,83	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,54	low_impact	-1,48	high_impact	3,03	0,25	0,8	47,06	9,61	P	0,65	P	0,62	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12089	12089	A	T	MI.19118	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1330	444	I	F	Att/Ttt	-9,18	0	0	benign	0,25	neutral	0,06	neutral	2,14	neutral	-1,21	neutral	-2,24	medium_impact	2,84	neutral	0,75	neutral	0,46	deleterious	2,27	17,94	0,16	0,45	disease	0,87	neutral	0,35	neutral	0,49	disease	0,66	3	neutral	0,93	neutral	0,41	neutral	-3	neutral	0,26	medium_impact	-0,27	medium_impact	-0,47	medium_impact	1,68	0,45	0,8	25,49	30,07	N	0,39	N	0,54	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12089	12089	A	C	MI.19119	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1330	444	I	L	Att/Ctt	-9,18	0	0	benign	0	neutral	1	neutral	2,38	neutral	0,92	neutral	0,56	neutral_impact	-0,28	neutral	0,8	neutral	0,97	neutral	-0,67	0,09	0,24	0,45	neutral	0,39	neutral	0,08	neutral	0,1	neutral	0,27	5	neutral	0	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,1	high_impact	1,88	low_impact	-1,4	0,5	0,8	25,49	30,07	N	0,4	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5919	5919	T	G	MI.1912	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	16	6	W	G	Tga/Gga	-4,96	0	0	probably_damaging	1	deleterious	0	deleterious	-1,85	deleterious	-6,18	neutral	-1,76	high_impact	4,03	neutral	0,65	damaging	0,08	deleterious	3,89	23,5	0,25	0,55	disease	0,92	disease	0,76	disease	0,83	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,62	0,24	0,9	3,12	6,72	N	0,36	N	0,9	polymorphism	0,98	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12089	12089	A	G	MI.19120	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1330	444	I	V	Att/Gtt	-9,18	0	0	benign	0,07	neutral	0,14	neutral	2,29	neutral	-1,56	neutral	-0,61	low_impact	1,8	neutral	0,76	neutral	0,87	neutral	-0,08	1,91	0,43	0,55	neutral	0,43	neutral	0,11	neutral	0,19	neutral	0,34	3	neutral	0,85	deleterious	0,54	neutral	-6	neutral	0,11	medium_impact	0,34	medium_impact	-0,24	medium_impact	0,66	0,31	0,8	25,49	30,07	P	0,59	P	0,6	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12090	12090	T	A	MI.19121	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1331	444	I	N	aTt/aAt	-0,2	0	0	possibly_damaging	0,51	deleterious	0,03	neutral	2,11	deleterious	-3,48	deleterious	-4,66	medium_impact	2,84	neutral	0,75	neutral	0,47	deleterious	2,82	21,5	0,15	0,4	disease	0,88	neutral	0,46	disease	0,52	disease	0,68	4	neutral	0,97	neutral	0,26	deleterious	4	deleterious	0,58	medium_impact	-0,73	medium_impact	-0,64	medium_impact	1,68	0,13	0,8	25,49	30,07	N	0,4	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12090	12090	T	C	MI.19122	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1331	444	I	T	aTt/aCt	-0,2	0	0	benign	0,01	deleterious	0,02	neutral	2,19	neutral	-2,28	deleterious	-2,8	low_impact	1,13	neutral	0,76	neutral	0,85	deleterious	0,48	7,27	0,14	0,4	disease	0,84	neutral	0,2	neutral	0,22	disease	0,5	0	neutral	0,98	deleterious	0,51	neutral	-2	neutral	0,26	medium_impact	1,16	medium_impact	-0,75	medium_impact	-0,01	0,26	0,8	25,49	30,07	N	0,39	N	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12090	12090	T	G	MI.19123	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1331	444	I	S	aTt/aGt	-0,2	0	0	benign	0,16	deleterious	0,03	neutral	2,14	neutral	-2,49	deleterious	-3,75	low_impact	1,94	neutral	0,76	neutral	0,72	deleterious	2,59	20,1	0,06	0,35	neutral	0,46	neutral	0,38	neutral	0,24	neutral	0,48	0	neutral	0,97	neutral	0,44	neutral	-2	neutral	0,32	medium_impact	-0,04	medium_impact	-0,64	medium_impact	0,79	0,16	0,8	25,49	30,07	N	0,47	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12091	12091	T	A	MI.19124	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1332	444	I	M	atT/atA	3,71	0,35	0	benign	0,43	neutral	0,23	neutral	2,16	neutral	-2,84	neutral	-0,37	neutral_impact	0,61	neutral	0,73	neutral	0,75	deleterious	0,67	8,62	0,34	0,5	disease	0,67	neutral	0,08	neutral	0,14	neutral	0,41	2	neutral	0,73	neutral	0,4	neutral	-6	neutral	0,25	medium_impact	-0,6	medium_impact	-0,09	medium_impact	-0,52	0,53	0,8	25,49	30,07	P	0,55	P	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12091	12091	T	G	MI.19125	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1332	444	I	M	atT/atG	3,71	0,35	0	benign	0,43	neutral	0,23	neutral	2,16	neutral	-2,84	neutral	-0,37	neutral_impact	0,61	neutral	0,73	neutral	0,75	deleterious	0,32	5,87	0,34	0,5	disease	0,67	neutral	0,08	neutral	0,14	neutral	0,41	2	neutral	0,73	neutral	0,4	neutral	-6	neutral	0,25	medium_impact	-0,6	medium_impact	-0,09	medium_impact	-0,52	0,53	0,8	25,49	30,07	P	0,54	P	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12092	12092	C	A	MI.19126	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1333	445	L	I	Ctc/Atc	-5,73	0	0,02	benign	0,02	neutral	0,4	neutral	2,26	neutral	-0,35	neutral	-0,47	neutral_impact	-0,17	neutral	0,77	neutral	0,97	deleterious	1,91	15,62	0,29	0,45	disease	0,76	neutral	0,11	neutral	0,09	neutral	0,39	2	neutral	0,58	deleterious	0,69	neutral	-6	deleterious	0,67	medium_impact	0,87	medium_impact	0,1	low_impact	-1,29	0,38	0,8	27,89	22,42	N	0,43	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12092	12092	C	G	MI.19127	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1333	445	L	V	Ctc/Gtc	-5,73	0	0,02	benign	0,21	neutral	0,51	neutral	2,21	neutral	-0,5	neutral	-1,16	low_impact	1,67	neutral	0,8	neutral	0,94	deleterious	2,35	18,48	0,27	0,45	disease	0,7	neutral	0,28	neutral	0,16	disease	0,59	2	neutral	0,39	deleterious	0,65	neutral	-6	deleterious	0,68	medium_impact	-0,18	medium_impact	0,21	medium_impact	0,53	0,49	0,8	27,89	22,42	N	0,4	N	0,43	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12092	12092	C	T	MI.19128	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1333	445	L	F	Ctc/Ttc	-5,73	0	0,02	possibly_damaging	0,74	neutral	0,7	neutral	2,09	neutral	-2,38	neutral	-2,42	low_impact	1,75	neutral	0,78	neutral	0,84	deleterious	4,09	23,7	0,24	0,45	disease	0,81	neutral	0,34	neutral	0,18	disease	0,65	3	neutral	0,69	deleterious	0,48	neutral	-3	deleterious	0,72	low_impact	-1,14	medium_impact	0,41	medium_impact	0,61	0,47	0,8	27,89	22,42	N	0,32	N	0,36	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12093	12093	T	C	MI.19129	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1334	445	L	P	cTc/cCc	-6,19	0	0	probably_damaging	0,92	neutral	0,2	neutral	2,04	deleterious	-4,35	deleterious	-5,08	medium_impact	3,21	neutral	0,62	neutral	0,37	deleterious	4,02	23,6	0,03	0,35	disease	0,87	disease	0,75	disease	0,65	disease	0,77	5	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,84	low_impact	-1,71	medium_impact	-0,14	high_impact	2,05	0,21	0,8	27,89	22,42	N	0,29	N	0,94	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5920	5920	G	C	MI.1913	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	17	6	W	S	tGa/tCa	7,53	1	0	probably_damaging	1	deleterious	0	deleterious	-1,86	deleterious	-5,39	neutral	-1,89	high_impact	3,83	neutral	0,64	damaging	0,09	deleterious	4	23,6	0,23	0,55	disease	0,87	disease	0,81	disease	0,81	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,44	0,2	0,9	3,12	6,72	P	0,52	P	0,88	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12093	12093	T	G	MI.19130	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1334	445	L	R	cTc/cGc	-6,19	0	0	probably_damaging	0,92	neutral	0,35	neutral	2,05	deleterious	-3,72	deleterious	-4,55	medium_impact	3,21	neutral	0,67	neutral	0,45	deleterious	4,27	24	0,02	0,35	disease	0,76	disease	0,78	disease	0,64	disease	0,76	5	neutral	0,92	neutral	0,22	deleterious	1	deleterious	0,82	low_impact	-1,71	medium_impact	0,05	high_impact	2,05	0,09	0,8	27,89	22,42	N	0,31	N	0,92	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12093	12093	T	A	MI.19131	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1334	445	L	H	cTc/cAc	-6,19	0	0	probably_damaging	0,94	neutral	0,54	neutral	2,04	deleterious	-4,33	deleterious	-5,04	medium_impact	3,21	neutral	0,74	neutral	0,54	deleterious	4,21	23,9	0,05	0,35	disease	0,86	disease	0,62	disease	0,59	disease	0,71	4	neutral	0,94	neutral	0,3	deleterious	1	deleterious	0,77	low_impact	-1,84	medium_impact	0,24	high_impact	2,05	0,13	0,8	27,89	22,42	N	0,28	N	0,84	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12095	12095	C	A	MI.19132	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1336	446	L	I	Ctc/Atc	-10,33	0	0	benign	0,42	neutral	0,2	neutral	2,17	deleterious	-3,61	neutral	-1,58	medium_impact	2,62	neutral	0,78	neutral	0,77	deleterious	3,14	22,6	0,3	0,45	disease	0,75	neutral	0,42	neutral	0,37	disease	0,62	2	neutral	0,77	neutral	0,39	neutral	-3	deleterious	0,71	medium_impact	-0,59	medium_impact	-0,14	medium_impact	1,47	0,42	0,8	16,99	17,81	N	0,38	N	0,15	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12095	12095	C	T	MI.19133	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1336	446	L	F	Ctc/Ttc	-10,33	0	0	benign	0,03	neutral	0,16	neutral	2,09	neutral	-1,32	deleterious	-3,4	medium_impact	2,67	neutral	0,72	neutral	0,64	deleterious	4,13	23,8	0,29	0,45	disease	0,83	neutral	0,42	neutral	0,43	disease	0,64	3	neutral	0,83	deleterious	0,57	neutral	-3	deleterious	0,75	medium_impact	0,7	medium_impact	-0,2	medium_impact	1,52	0,52	0,8	16,99	17,81	N	0,42	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12095	12095	C	G	MI.19134	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1336	446	L	V	Ctc/Gtc	-10,33	0	0	benign	0,42	deleterious	0,03	neutral	2,17	neutral	-1,44	neutral	-2,43	medium_impact	3,26	neutral	0,69	neutral	0,53	deleterious	3,56	23,1	0,29	0,45	disease	0,67	neutral	0,46	disease	0,57	disease	0,63	3	neutral	0,97	neutral	0,31	deleterious	1	deleterious	0,72	medium_impact	-0,59	medium_impact	-0,64	high_impact	2,1	0,54	0,8	16,99	17,81	N	0,41	N	0,66	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12096	12096	T	G	MI.19135	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1337	446	L	R	cTc/cGc	0,49	0,1	0	possibly_damaging	0,84	deleterious	0	neutral	2,04	deleterious	-3,66	deleterious	-5,18	high_impact	4,07	damaging	0,56	neutral	0,4	deleterious	4,36	24,1	0,03	0,35	disease	0,55	disease	0,83	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,08	deleterious	5	deleterious	0,81	low_impact	-1,39	low_impact	-1,48	high_impact	2,9	0,12	0,8	16,99	17,81	N	0,44	N	0,98	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12096	12096	T	C	MI.19136	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1337	446	L	P	cTc/cCc	0,49	0,1	0	possibly_damaging	0,88	deleterious	0,01	neutral	2,01	deleterious	-4,87	deleterious	-6,01	medium_impact	3,17	damaging	0,57	neutral	0,46	deleterious	4,02	23,6	0,03	0,35	disease	0,74	disease	0,72	disease	0,66	disease	0,64	3	deleterious	1	neutral	0,07	deleterious	4	deleterious	0,82	low_impact	-1,53	medium_impact	-0,92	high_impact	2,01	0,27	0,8	16,99	17,81	N	0,36	N	0,94	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12096	12096	T	A	MI.19137	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1337	446	L	H	cTc/cAc	0,49	0,1	0	probably_damaging	0,94	deleterious	0	neutral	2,01	neutral	-1,89	deleterious	-6,03	high_impact	4,07	neutral	0,63	neutral	0,4	deleterious	4,31	24	0,06	0,35	disease	0,56	disease	0,73	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,75	low_impact	-1,84	low_impact	-1,48	high_impact	2,9	0,12	0,8	16,99	17,81	N	0,45	N	0,86	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12098	12098	C	A	MI.19138	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1339	447	L	M	Cta/Ata	-20	0	0	probably_damaging	1	neutral	0,17	neutral	2	neutral	-1,06	neutral	-1,59	medium_impact	2,69	neutral	0,78	damaging	0,21	deleterious	3,86	23,5	0,23	0,45	disease	0,59	neutral	0,39	neutral	0,36	disease	0,57	1	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,71	low_impact	-3,54	medium_impact	-0,18	medium_impact	1,54	0,48	0,8	17,21	14,68	N	0,34	N	0,65	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12098	12098	C	G	MI.19139	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1339	447	L	V	Cta/Gta	-20	0	0	probably_damaging	1	deleterious	0,03	neutral	2,07	neutral	0,21	neutral	-2,27	medium_impact	2,94	neutral	0,65	damaging	0,15	deleterious	3,54	23,1	0,27	0,45	disease	0,74	neutral	0,5	neutral	0,46	neutral	0,49	0	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,74	low_impact	-3,54	medium_impact	-0,64	medium_impact	1,78	0,51	0,8	17,21	14,68	N	0,32	N	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5920	5920	G	T	MI.1914	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	17	6	W	L	tGa/tTa	7,53	1	0	probably_damaging	1	deleterious	0	deleterious	-1,85	deleterious	-3,75	neutral	-1,75	medium_impact	2,79	neutral	0,69	damaging	0,07	deleterious	4,26	23,9	0,19	0,55	disease	0,71	disease	0,69	disease	0,82	disease	0,78	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	medium_impact	1,48	0,19	0,9	3,12	6,72	N	0,5	N	0,95	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12099	12099	T	A	MI.19140	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1340	447	L	Q	cTa/cAa	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	1,94	neutral	-2,83	deleterious	-5,04	high_impact	4,04	neutral	0,61	damaging	0,12	deleterious	4,23	23,9	0,05	0,35	disease	0,95	disease	0,73	disease	0,62	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,54	low_impact	-1,48	high_impact	2,87	0,13	0,8	17,21	14,68	N	0,31	N	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12099	12099	T	C	MI.19141	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1340	447	L	P	cTa/cCa	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	1,94	deleterious	-3,66	deleterious	-5,85	high_impact	4,04	damaging	0,54	damaging	0,13	deleterious	4,07	23,7	0,04	0,35	disease	0,96	disease	0,77	disease	0,75	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,54	low_impact	-1,48	high_impact	2,87	0,16	0,8	17,21	14,68	N	0,33	N	0,94	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12099	12099	T	G	MI.19142	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1340	447	L	R	cTa/cGa	-0,2	0	0	probably_damaging	1	deleterious	0	neutral	1,95	neutral	-0,16	deleterious	-5,04	high_impact	4,04	neutral	0,68	damaging	0,13	deleterious	4,35	24,1	0,03	0,35	disease	0,95	disease	0,84	disease	0,75	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,54	low_impact	-1,48	high_impact	2,87	0,1	0,8	17,21	14,68	N	0,31	N	0,98	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12101	12101	T	A	MI.19143	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1342	448	S	T	Tcc/Acc	-4,81	0	0	benign	0,01	neutral	0,13	neutral	2,29	neutral	0,74	neutral	0,45	neutral_impact	0,51	neutral	0,88	neutral	0,98	deleterious	0,21	4,75	0,32	0,5	neutral	0,49	neutral	0,23	neutral	0,17	neutral	0,4	2	neutral	0,87	deleterious	0,56	neutral	-6	neutral	0,14	medium_impact	1,16	medium_impact	-0,26	medium_impact	-0,62	0,62	0,8	25,05	16,6	P	0,57	P	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12101	12101	T	C	MI.19144	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1342	448	S	P	Tcc/Ccc	-4,81	0	0	possibly_damaging	0,7	deleterious	0,01	neutral	2,22	deleterious	-3,04	neutral	-2,24	medium_impact	3,19	neutral	0,75	neutral	0,41	deleterious	2,25	17,87	0,09	0,35	neutral	0,47	disease	0,82	neutral	0,49	disease	0,73	5	deleterious	0,99	neutral	0,16	deleterious	4	neutral	0,43	low_impact	-1,06	medium_impact	-0,92	high_impact	2,03	0,22	0,8	25,05	16,6	N	0,4	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12101	12101	T	G	MI.19145	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1342	448	S	A	Tcc/Gcc	-4,81	0	0	benign	0,22	deleterious	0,02	neutral	2,31	neutral	-0,8	neutral	-0,74	medium_impact	2,08	neutral	0,76	neutral	0,76	deleterious	0,7	8,85	0,32	0,5	neutral	0,47	neutral	0,31	neutral	0,35	neutral	0,46	1	neutral	0,98	neutral	0,4	deleterious	1	neutral	0,19	medium_impact	-0,2	medium_impact	-0,75	medium_impact	0,93	0,34	0,8	25,05	16,6	N	0,46	N	0,33	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12102	12102	C	G	MI.19146	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1343	448	S	C	tCc/tGc	-0,2	0	0	possibly_damaging	0,87	deleterious	0,04	neutral	2,21	neutral	-2,82	neutral	-1,61	medium_impact	2,84	neutral	0,68	neutral	0,41	deleterious	3,31	22,9	0,11	0,4	disease	0,86	disease	0,61	neutral	0,49	disease	0,59	2	deleterious	0,98	neutral	0,09	deleterious	4	deleterious	0,63	low_impact	-1,49	medium_impact	-0,57	medium_impact	1,68	0,24	0,8	25,05	16,6	N	0,39	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12102	12102	C	A	MI.19147	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1343	448	S	Y	tCc/tAc	-0,2	0	0	possibly_damaging	0,87	deleterious	0,04	neutral	2,23	neutral	-2,01	neutral	-2,13	medium_impact	3,19	neutral	0,73	neutral	0,49	deleterious	2,75	21,1	0,09	0,35	disease	0,78	disease	0,63	disease	0,54	disease	0,7	4	deleterious	0,98	neutral	0,09	deleterious	4	deleterious	0,6	low_impact	-1,49	medium_impact	-0,57	high_impact	2,03	0,18	0,8	25,05	16,6	N	0,42	N	0,99	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12102	12102	C	T	MI.19148	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1343	448	S	F	tCc/tTc	-0,2	0	0	possibly_damaging	0,82	neutral	0,3	neutral	2,26	neutral	1,45	neutral	-1,81	medium_impact	2,04	neutral	0,71	neutral	0,48	deleterious	2,76	21,1	0,09	0,35	disease	0,69	disease	0,64	neutral	0,28	disease	0,53	1	neutral	0,85	neutral	0,24	NA	0	deleterious	0,58	low_impact	-1,34	medium_impact	0	medium_impact	0,89	0,09	0,8	25,05	16,6	N	0,38	N	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12104	12104	C	A	MI.19149	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1345	449	L	I	Ctc/Atc	-8,72	0	0	benign	0,06	neutral	0,27	neutral	2,19	neutral	-0,7	neutral	-0,62	medium_impact	1,98	neutral	0,83	neutral	0,98	deleterious	0,83	9,65	0,35	0,5	neutral	0,37	neutral	0,21	neutral	0,13	neutral	0,38	2	neutral	0,7	deleterious	0,61	neutral	-3	neutral	0,13	medium_impact	0,41	medium_impact	-0,04	medium_impact	0,83	0,61	0,8	25,27	18,67	P	0,57	P	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5921	5921	A	C	MI.1915	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	18	6	W	C	tgA/tgC	6,14	1	0	probably_damaging	1	deleterious	0	deleterious	-1,86	deleterious	-6,93	neutral	-1,76	high_impact	4,03	damaging	0,58	damaging	0,07	deleterious	4,03	23,6	0,28	0,55	disease	0,95	disease	0,79	disease	0,85	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,62	0,2	0,9	3,12	6,72	P	0,51	P	0,88	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12104	12104	C	T	MI.19150	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1345	449	L	F	Ctc/Ttc	-8,72	0	0	possibly_damaging	0,78	neutral	0,29	neutral	2,06	neutral	-2,35	neutral	-2,19	low_impact	1,94	neutral	0,74	neutral	0,84	neutral	1,28	12,15	0,22	0,45	disease	0,62	neutral	0,32	neutral	0,17	disease	0,61	2	neutral	0,83	neutral	0,26	neutral	-3	deleterious	0,5	low_impact	-1,23	medium_impact	-0,02	medium_impact	0,79	0,36	0,8	25,27	18,67	N	0,45	N	0,71	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12104	12104	C	G	MI.19151	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1345	449	L	V	Ctc/Gtc	-8,72	0	0	benign	0,15	neutral	0,14	neutral	2,18	neutral	-0,45	neutral	-1,15	medium_impact	2,86	neutral	0,78	neutral	0,88	deleterious	0,57	7,92	0,37	0,5	disease	0,56	neutral	0,3	neutral	0,34	disease	0,6	2	neutral	0,84	deleterious	0,5	neutral	-3	neutral	0,21	medium_impact	-0,01	medium_impact	-0,24	medium_impact	1,7	0,63	0,8	25,27	18,67	N	0,45	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12105	12105	T	G	MI.19152	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1346	449	L	R	cTc/cGc	-4,35	0	0	probably_damaging	0,93	deleterious	0	neutral	1,99	deleterious	-4,17	deleterious	-3,97	high_impact	3,75	neutral	0,68	neutral	0,44	deleterious	4,04	23,7	0,02	0,35	disease	0,71	disease	0,75	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,72	low_impact	-1,77	low_impact	-1,48	high_impact	2,58	0,1	0,8	25,27	18,67	N	0,39	N	0,96	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12105	12105	T	C	MI.19153	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1346	449	L	P	cTc/cCc	-4,35	0	0	probably_damaging	0,95	deleterious	0	neutral	1,98	deleterious	-4,71	deleterious	-4,55	high_impact	3,75	neutral	0,64	neutral	0,38	deleterious	3,81	23,4	0,02	0,35	disease	0,9	disease	0,75	disease	0,55	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,78	low_impact	-1,92	low_impact	-1,48	high_impact	2,58	0,21	0,8	25,27	18,67	N	0,37	N	0,94	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12105	12105	T	A	MI.19154	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1346	449	L	H	cTc/cAc	-4,35	0	0	probably_damaging	0,95	deleterious	0	neutral	1,98	deleterious	-4,81	deleterious	-4,55	high_impact	3,75	neutral	0,74	neutral	0,52	deleterious	4,09	23,7	0,03	0,35	disease	0,84	disease	0,65	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,74	low_impact	-1,92	low_impact	-1,48	high_impact	2,58	0,26	0,8	25,27	18,67	N	0,41	N	0,84	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12107	12107	A	T	MI.19155	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1348	450	N	Y	Aac/Tac	-10,1	0	0	probably_damaging	0,96	neutral	0,07	neutral	2,35	neutral	0,07	deleterious	-5,35	medium_impact	2,34	neutral	0,75	damaging	0,17	deleterious	3,86	23,5	0,15	0,4	disease	0,52	disease	0,64	neutral	0,4	neutral	0,49	0	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,75	low_impact	-2,01	medium_impact	-0,43	medium_impact	1,19	0,23	0,8	13,73	8,17	N	0,34	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12107	12107	A	C	MI.19156	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1348	450	N	H	Aac/Cac	-10,1	0	0	probably_damaging	0,96	deleterious	0,03	neutral	2,27	deleterious	-3,11	deleterious	-3,27	low_impact	1,83	neutral	0,8	damaging	0,18	deleterious	3,22	22,7	0,35	0,5	disease	0,71	disease	0,56	disease	0,6	disease	0,68	4	deleterious	0,99	neutral	0,04	deleterious	2	deleterious	0,76	low_impact	-2,01	medium_impact	-0,64	medium_impact	0,68	0,24	0,8	13,73	8,17	N	0,27	N	0,81	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12107	12107	A	G	MI.19157	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1348	450	N	D	Aac/Gac	-10,1	0	0	benign	0,05	deleterious	0,03	neutral	2,29	neutral	-2,89	deleterious	-3,21	medium_impact	2,75	neutral	0,8	neutral	0,36	deleterious	3,88	23,5	0,46	0,55	disease	0,56	disease	0,56	disease	0,55	disease	0,59	2	neutral	0,97	deleterious	0,49	deleterious	1	deleterious	0,73	medium_impact	0,48	medium_impact	-0,64	medium_impact	1,6	0,34	0,8	13,73	8,17	N	0,36	N	0,88	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12108	12108	A	C	MI.19158	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1349	450	N	T	aAc/aCc	8,55	1	0	possibly_damaging	0,78	deleterious	0,02	neutral	2,32	neutral	-0,48	deleterious	-3,8	medium_impact	2,89	neutral	0,71	damaging	0,18	deleterious	3,96	23,6	0,25	0,45	neutral	0,28	neutral	0,44	disease	0,63	neutral	0,48	0	deleterious	0,99	neutral	0,12	deleterious	4	deleterious	0,68	low_impact	-1,23	medium_impact	-0,75	medium_impact	1,73	0,28	0,8	13,73	8,17	P	0,65	P	0,78	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12108	12108	A	G	MI.19159	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1349	450	N	S	aAc/aGc	8,55	1	0	possibly_damaging	0,52	neutral	0,08	neutral	2,33	neutral	1,08	deleterious	-2,86	low_impact	1,57	neutral	0,81	neutral	0,86	deleterious	2,56	19,83	0,44	0,55	neutral	0,32	neutral	0,45	neutral	0,35	neutral	0,43	1	neutral	0,91	neutral	0,28	neutral	-3	deleterious	0,69	medium_impact	-0,75	medium_impact	-0,39	medium_impact	0,43	0,16	0,8	13,73	8,17	P	0,63	P	0,46	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5921	5921	A	T	MI.1916	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	18	6	W	C	tgA/tgT	6,14	1	0	probably_damaging	1	deleterious	0	deleterious	-1,86	deleterious	-6,93	neutral	-1,76	high_impact	4,03	damaging	0,58	damaging	0,07	deleterious	4,14	23,8	0,28	0,55	disease	0,95	disease	0,79	disease	0,85	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,62	0,2	0,9	3,12	6,72	P	0,52	P	0,88	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12108	12108	A	T	MI.19160	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1349	450	N	I	aAc/aTc	8,55	1	0	probably_damaging	0,92	neutral	0,06	neutral	2,31	neutral	-0,09	deleterious	-6,2	medium_impact	3,09	neutral	0,72	damaging	0,18	deleterious	4,59	24,4	0,16	0,45	disease	0,68	disease	0,73	disease	0,62	disease	0,7	4	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,77	low_impact	-1,71	medium_impact	-0,47	medium_impact	1,93	0,2	0,8	13,73	8,17	P	0,63	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12109	12109	C	A	MI.19161	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1350	450	N	K	aaC/aaA	4,63	1	0	possibly_damaging	0,73	neutral	1	neutral	2,39	neutral	-1,93	neutral	-2,22	neutral_impact	0,72	neutral	0,67	neutral	0,8	deleterious	1,87	15,4	0,39	0,5	neutral	0,32	neutral	0,09	neutral	0,27	neutral	0,23	5	neutral	0,73	deleterious	0,64	neutral	-3	deleterious	0,66	low_impact	-1,12	high_impact	1,88	medium_impact	-0,41	0,32	0,8	13,73	8,17	P	0,53	P	0,9	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12109	12109	C	G	MI.19162	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1350	450	N	K	aaC/aaG	4,63	1	0	possibly_damaging	0,73	neutral	1	neutral	2,39	neutral	-1,93	neutral	-2,22	neutral_impact	0,72	neutral	0,67	neutral	0,8	neutral	1,43	12,93	0,39	0,5	neutral	0,32	neutral	0,09	neutral	0,27	neutral	0,23	5	neutral	0,73	deleterious	0,64	neutral	-3	deleterious	0,66	low_impact	-1,12	high_impact	1,88	medium_impact	-0,41	0,32	0,8	13,73	8,17	P	0,53	P	0,9	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12110	12110	C	A	MI.19163	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1351	451	P	T	Ccc/Acc	-4,35	0	0	probably_damaging	1	neutral	0,06	neutral	2,04	deleterious	-3,14	deleterious	-7,17	medium_impact	3,35	neutral	0,64	neutral	0,4	deleterious	3,99	23,6	0,08	0,35	disease	0,63	disease	0,6	disease	0,6	disease	0,58	2	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,47	high_impact	2,19	0,5	0,8	46,62	9,54	N	0,38	N	0,88	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12110	12110	C	G	MI.19164	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1351	451	P	A	Ccc/Gcc	-4,35	0	0	probably_damaging	1	neutral	0,05	neutral	2,07	neutral	-2,46	deleterious	-7,17	high_impact	4,15	neutral	0,65	neutral	0,48	deleterious	3,24	22,8	0,1	0,4	disease	0,62	neutral	0,46	disease	0,73	disease	0,64	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,75	low_impact	-3,54	medium_impact	-0,52	high_impact	2,98	0,65	0,8	46,62	9,54	N	0,45	N	0,74	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12110	12110	C	T	MI.19165	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1351	451	P	S	Ccc/Tcc	-4,35	0	0	probably_damaging	1	neutral	0,22	neutral	2,06	neutral	-2,64	deleterious	-7,17	medium_impact	3,17	neutral	0,65	neutral	0,45	deleterious	3,99	23,6	0,08	0,35	disease	0,55	disease	0,59	disease	0,56	neutral	0,45	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,11	high_impact	2,01	0,13	0,8	46,62	9,54	N	0,35	N	0,68	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12111	12111	C	A	MI.19166	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1352	451	P	H	cCc/cAc	5,32	1	0	probably_damaging	1	deleterious	0,03	neutral	1,99	deleterious	-4,85	deleterious	-8,05	high_impact	3,81	neutral	0,65	neutral	0,34	deleterious	4,16	23,8	0,04	0,35	disease	0,8	disease	0,76	disease	0,8	disease	0,83	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-3,54	medium_impact	-0,64	high_impact	2,64	0,23	0,8	46,62	9,54	P	0,62	P	0,7	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12111	12111	C	G	MI.19167	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1352	451	P	R	cCc/cGc	5,32	1	0	probably_damaging	1	deleterious	0,02	neutral	2,02	deleterious	-3,58	deleterious	-8,06	high_impact	4,15	neutral	0,63	neutral	0,42	deleterious	3,77	23,4	0,03	0,35	disease	0,64	disease	0,79	disease	0,83	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,54	medium_impact	-0,75	high_impact	2,98	0,21	0,8	46,62	9,54	P	0,65	P	0,62	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12111	12111	C	T	MI.19168	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1352	451	P	L	cCc/cTc	5,32	1	0	probably_damaging	1	neutral	0,11	neutral	2,04	deleterious	-3,49	deleterious	-8,96	medium_impact	3,05	neutral	0,62	neutral	0,42	deleterious	4,55	24,4	0,04	0,35	disease	0,78	disease	0,76	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,31	medium_impact	1,89	0,52	0,8	46,62	9,54	P	0,59	P	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12113	12113	G	T	MI.19169	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1354	452	D	Y	Gac/Tac	-10,33	0	0	benign	0,4	neutral	0,06	neutral	2,22	neutral	1,1	neutral	-1,58	low_impact	0,86	neutral	0,75	neutral	0,62	deleterious	2,31	18,25	0,08	0,35	neutral	0,47	disease	0,5	disease	0,57	disease	0,7	4	neutral	0,93	neutral	0,33	neutral	-6	neutral	0,42	medium_impact	-0,55	medium_impact	-0,47	medium_impact	-0,28	0,08	0,8	22	30,03	N	0,41	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5922	5922	C	G	MI.1917	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	19	7	L	V	Cta/Gta	3,83	0,99	0	possibly_damaging	0,89	deleterious	0,03	neutral	-0,95	neutral	-0,62	neutral	-0,31	medium_impact	2,1	neutral	0,65	damaging	0,15	neutral	1,51	13,39	0,39	0,55	neutral	0,3	neutral	0,39	neutral	0,28	neutral	0,46	1	deleterious	0,99	neutral	0,07	deleterious	4	deleterious	0,65	low_impact	-1,61	medium_impact	-0,65	medium_impact	0,84	0,69	0,9	7,99	10,87	P	0,53	P	0,64	disease_causing	0,93	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12113	12113	G	A	MI.19170	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1354	452	D	N	Gac/Aac	-10,33	0	0	benign	0	neutral	0,18	neutral	2,3	neutral	0,07	neutral	0,16	neutral_impact	-1,07	neutral	0,79	neutral	0,85	neutral	1,18	11,65	0,72	0,75	neutral	0,34	neutral	0,26	neutral	0,17	neutral	0,45	1	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,11	high_impact	2,1	medium_impact	-0,17	low_impact	-2,18	0,62	0,8	22	30,03	N	0,49	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12113	12113	G	C	MI.19171	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1354	452	D	H	Gac/Cac	-10,33	0	0	benign	0,4	deleterious	0,02	neutral	2,24	neutral	-2,09	neutral	-0,42	neutral_impact	0,72	neutral	0,74	neutral	0,62	deleterious	2,03	16,38	0,16	0,45	disease	0,6	neutral	0,36	neutral	0,42	disease	0,61	2	neutral	0,98	neutral	0,31	neutral	-2	neutral	0,35	medium_impact	-0,55	medium_impact	-0,75	medium_impact	-0,41	0,51	0,8	22	30,03	N	0,43	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12114	12114	A	T	MI.19172	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1355	452	D	V	gAc/gTc	0,95	0	0	benign	0,05	neutral	0,07	neutral	2,24	neutral	-0,09	neutral	-1,75	low_impact	1,42	neutral	0,79	neutral	0,7	deleterious	2,16	17,27	0,05	0,35	disease	0,57	neutral	0,47	disease	0,54	disease	0,65	3	neutral	0,93	deleterious	0,51	neutral	-6	neutral	0,23	medium_impact	0,48	medium_impact	-0,43	medium_impact	0,28	0,12	0,8	22	30,03	N	0,38	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12114	12114	A	G	MI.19173	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1355	452	D	G	gAc/gGc	0,95	0	0	benign	0,05	neutral	0,16	neutral	2,25	neutral	2,38	neutral	-1,62	neutral_impact	0,06	neutral	0,73	neutral	0,75	deleterious	2,26	17,9	0,14	0,4	disease	0,55	neutral	0,34	neutral	0,42	disease	0,6	2	neutral	0,83	deleterious	0,56	neutral	-6	neutral	0,14	medium_impact	0,48	medium_impact	-0,2	low_impact	-1,07	0,38	0,8	22	30,03	N	0,43	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12114	12114	A	C	MI.19174	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1355	452	D	A	gAc/gCc	0,95	0	0	benign	0,03	neutral	0,19	neutral	2,32	neutral	0,84	neutral	-0,79	neutral_impact	0	neutral	0,67	neutral	0,86	deleterious	0,8	9,48	0,13	0,4	neutral	0,35	neutral	0,23	neutral	0,44	neutral	0,44	1	neutral	0,8	deleterious	0,58	neutral	-6	neutral	0,12	medium_impact	0,7	medium_impact	-0,15	low_impact	-1,13	0,3	0,8	22	30,03	N	0,48	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12115	12115	C	A	MI.19175	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1356	452	D	E	gaC/gaA	0,72	0	0	benign	0,05	neutral	1	neutral	2,38	neutral	-0,85	neutral	1,64	neutral_impact	-1,12	neutral	0,67	neutral	0,78	neutral	-0,29	0,68	0,39	0,5	neutral	0,28	neutral	0,08	neutral	0,1	neutral	0,26	5	neutral	0,05	deleterious	0,98	neutral	-6	neutral	0,1	medium_impact	0,48	high_impact	1,88	low_impact	-2,23	0,57	0,8	22	30,03	N	0,38	N	0,23	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12115	12115	C	G	MI.19176	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1356	452	D	E	gaC/gaG	0,72	0	0	benign	0,05	neutral	1	neutral	2,38	neutral	-0,85	neutral	1,64	neutral_impact	-1,12	neutral	0,67	neutral	0,78	neutral	-0,64	0,1	0,39	0,5	neutral	0,28	neutral	0,08	neutral	0,1	neutral	0,26	5	neutral	0,05	deleterious	0,98	neutral	-6	neutral	0,1	medium_impact	0,48	high_impact	1,88	low_impact	-2,23	0,57	0,8	22	30,03	N	0,37	N	0,23	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12116	12116	A	T	MI.19177	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1357	453	I	F	Atc/Ttc	-0,89	0	0	possibly_damaging	0,47	neutral	0,27	neutral	2,21	neutral	-0,76	neutral	-2,06	low_impact	1,7	neutral	0,75	neutral	0,92	deleterious	2,5	19,44	0,15	0,4	disease	0,6	neutral	0,4	neutral	0,24	disease	0,62	2	neutral	0,7	neutral	0,4	neutral	-3	deleterious	0,7	medium_impact	-0,67	medium_impact	-0,04	medium_impact	0,56	0,65	0,8	30,94	17,28	N	0,43	N	0,45	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12116	12116	A	C	MI.19178	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1357	453	I	L	Atc/Ctc	-0,89	0	0	benign	0,01	neutral	1	neutral	2,42	neutral	2,09	neutral	0,17	neutral_impact	0,08	neutral	0,67	neutral	0,94	neutral	0,9	10,05	0,21	0,45	neutral	0,29	neutral	0,07	neutral	0,14	neutral	0,23	5	neutral	0,01	deleterious	1	neutral	-6	deleterious	0,49	medium_impact	1,16	high_impact	1,88	low_impact	-1,05	0,52	0,8	30,94	17,28	N	0,49	N	0,16	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12116	12116	A	G	MI.19179	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1357	453	I	V	Atc/Gtc	-0,89	0	0	benign	0,01	neutral	0,08	neutral	2,3	neutral	3,09	neutral	-0,78	low_impact	1,02	neutral	0,84	neutral	0,96	neutral	1,77	14,79	0,54	0,6	neutral	0,28	neutral	0,14	neutral	0,39	neutral	0,3	4	neutral	0,92	deleterious	0,54	neutral	-6	deleterious	0,5	medium_impact	1,16	medium_impact	-0,39	medium_impact	-0,12	0,5	0,8	30,94	17,28	N	0,47	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5922	5922	C	A	MI.1918	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	19	7	L	M	Cta/Ata	3,83	0,99	0	probably_damaging	0,99	neutral	0,05	neutral	-0,97	neutral	-2,63	neutral	-0,19	medium_impact	2,34	neutral	0,64	damaging	0,27	neutral	0,91	10,13	0,3	0,55	neutral	0,39	neutral	0,31	neutral	0,26	neutral	0,47	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,69	low_impact	-2,64	medium_impact	-0,52	medium_impact	1,06	0,72	0,9	7,99	10,87	P	0,58	P	0,55	disease_causing	0,91	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12117	12117	T	A	MI.19180	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1358	453	I	N	aTc/aAc	-0,2	0	0	possibly_damaging	0,64	deleterious	0,01	neutral	2,15	neutral	1,55	deleterious	-4,91	medium_impact	2,9	neutral	0,66	neutral	0,54	deleterious	4,59	24,4	0,17	0,45	neutral	0,38	disease	0,57	disease	0,59	disease	0,71	4	deleterious	0,99	neutral	0,19	deleterious	4	deleterious	0,73	medium_impact	-0,95	medium_impact	-0,92	medium_impact	1,74	0,13	0,8	30,94	17,28	N	0,4	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12117	12117	T	C	MI.19181	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1358	453	I	T	aTc/aCc	-0,2	0	0	benign	0,02	deleterious	0,04	neutral	2,21	neutral	1,57	deleterious	-3,12	low_impact	1,86	neutral	0,79	neutral	0,85	deleterious	3,45	23	0,17	0,45	neutral	0,5	neutral	0,25	neutral	0,46	neutral	0,42	2	neutral	0,96	deleterious	0,51	neutral	-2	deleterious	0,69	medium_impact	0,87	medium_impact	-0,57	medium_impact	0,71	0,31	0,8	30,94	17,28	N	0,42	N	0,91	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12117	12117	T	G	MI.19182	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1358	453	I	S	aTc/aGc	-0,2	0	0	benign	0,24	deleterious	0,03	neutral	2,19	neutral	3,34	deleterious	-4,02	low_impact	1,7	neutral	0,7	neutral	0,59	deleterious	4,4	24,1	0,06	0,35	neutral	0,45	neutral	0,5	disease	0,59	disease	0,65	3	neutral	0,97	neutral	0,4	neutral	-2	deleterious	0,71	medium_impact	-0,25	medium_impact	-0,64	medium_impact	0,56	0,21	0,8	30,94	17,28	N	0,37	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12118	12118	C	G	MI.19183	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1359	453	I	M	atC/atG	3,71	0,52	0	possibly_damaging	0,55	neutral	0,09	neutral	2,19	neutral	-0,33	neutral	-0,97	low_impact	1,23	neutral	0,81	neutral	0,97	deleterious	3,7	23,3	0,33	0,5	neutral	0,24	neutral	0,22	neutral	0,23	neutral	0,41	2	neutral	0,91	neutral	0,27	neutral	-3	deleterious	0,66	medium_impact	-0,8	medium_impact	-0,36	medium_impact	0,09	0,62	0,8	30,94	17,28	N	0,46	N	0,6	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12118	12118	C	A	MI.19184	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1359	453	I	M	atC/atA	3,71	0,52	0	possibly_damaging	0,55	neutral	0,09	neutral	2,19	neutral	-0,33	neutral	-0,97	low_impact	1,23	neutral	0,81	neutral	0,97	deleterious	4,23	23,9	0,33	0,5	neutral	0,24	neutral	0,22	neutral	0,23	neutral	0,41	2	neutral	0,91	neutral	0,27	neutral	-3	deleterious	0,66	medium_impact	-0,8	medium_impact	-0,36	medium_impact	0,09	0,62	0,8	30,94	17,28	N	0,46	N	0,6	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12119	12119	A	G	MI.19185	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1360	454	I	V	Att/Gtt	-7,11	0	0	probably_damaging	0,99	neutral	0,18	neutral	2,27	neutral	-0,27	neutral	-0,75	low_impact	1,61	neutral	0,73	neutral	0,87	deleterious	2,11	16,94	0,61	0,65	neutral	0,41	neutral	0,11	neutral	0,33	neutral	0,31	4	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,51	low_impact	-2,59	medium_impact	-0,17	medium_impact	0,47	0,44	0,8	45,32	10,07	N	0,48	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12119	12119	A	C	MI.19186	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1360	454	I	L	Att/Ctt	-7,11	0	0	probably_damaging	0,99	neutral	0,28	neutral	2,24	neutral	-1,54	neutral	-1,42	low_impact	1,78	neutral	0,64	neutral	0,31	deleterious	3,92	23,5	0,28	0,45	neutral	0,25	neutral	0,31	neutral	0,31	neutral	0,43	1	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,52	low_impact	-2,59	medium_impact	-0,03	medium_impact	0,64	0,67	0,85	45,32	10,07	N	0,38	N	0,85	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12119	12119	A	T	MI.19187	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1360	454	I	F	Att/Ttt	-7,11	0	0	probably_damaging	1	neutral	0,33	neutral	2,07	neutral	-2,89	deleterious	-3,23	medium_impact	2,69	neutral	0,68	damaging	0,18	deleterious	4,08	23,7	0,17	0,45	disease	0,59	neutral	0,47	disease	0,51	disease	0,58	2	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,7	low_impact	-3,54	medium_impact	0,03	medium_impact	1,54	0,66	0,8	45,32	10,07	N	0,29	N	0,96	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12120	12120	T	A	MI.19188	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1361	454	I	N	aTt/aAt	1,87	0,88	0	probably_damaging	1	deleterious	0,02	neutral	2	neutral	0,03	deleterious	-5,78	medium_impact	3,38	damaging	0,56	damaging	0,17	deleterious	4,78	24,7	0,08	0,35	disease	0,75	disease	0,63	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,54	medium_impact	-0,75	high_impact	2,22	0,08	0,8	45,32	10,07	N	0,38	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12120	12120	T	C	MI.19189	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1361	454	I	T	aTt/aCt	1,87	0,88	0	probably_damaging	1	deleterious	0,02	neutral	2,05	neutral	-0,56	deleterious	-4,06	medium_impact	2,75	neutral	0,76	damaging	0,28	deleterious	3,68	23,3	0,07	0,35	neutral	0,25	neutral	0,4	disease	0,6	neutral	0,45	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,67	low_impact	-3,54	medium_impact	-0,75	medium_impact	1,6	0,19	0,8	45,32	10,07	N	0,4	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5923	5923	T	A	MI.1919	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	20	7	L	Q	cTa/cAa	-1,49	0	0	probably_damaging	0,99	deleterious	0	neutral	-1,01	deleterious	-3,8	neutral	-0,72	high_impact	3,75	neutral	0,64	damaging	0,13	deleterious	3,98	23,6	0,18	0,55	disease	0,7	disease	0,72	disease	0,6	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,64	low_impact	-1,48	high_impact	2,36	0,6	0,9	7,99	10,87	N	0,37	N	0,84	disease_causing	0,83	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12120	12120	T	G	MI.19190	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1361	454	I	S	aTt/aGt	1,87	0,88	0	probably_damaging	1	neutral	0,06	neutral	2,02	neutral	-2,06	deleterious	-4,88	medium_impact	3,04	damaging	0,6	damaging	0,16	deleterious	4,58	24,4	0,02	0,35	disease	0,62	disease	0,64	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,47	medium_impact	1,88	0,1	0,8	45,32	10,07	N	0,37	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12121	12121	T	G	MI.19191	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1362	454	I	M	atT/atG	5,55	0,98	0	probably_damaging	1	neutral	0,27	neutral	2,06	neutral	-2,91	neutral	-1,91	low_impact	1,5	neutral	0,72	neutral	0,43	deleterious	2,27	17,98	0,27	0,45	neutral	0,46	neutral	0,21	neutral	0,33	neutral	0,37	3	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,67	low_impact	-3,54	medium_impact	-0,04	medium_impact	0,36	0,51	0,8	45,32	10,07	P	0,67	P	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12121	12121	T	A	MI.19192	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1362	454	I	M	atT/atA	5,55	0,98	0	probably_damaging	1	neutral	0,27	neutral	2,06	neutral	-2,91	neutral	-1,91	low_impact	1,5	neutral	0,72	neutral	0,43	deleterious	2,56	19,87	0,27	0,45	neutral	0,46	neutral	0,21	neutral	0,33	neutral	0,37	3	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,67	low_impact	-3,54	medium_impact	-0,04	medium_impact	0,36	0,51	0,8	45,32	10,07	P	0,67	P	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12122	12122	A	C	MI.19193	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1363	455	T	P	Acc/Ccc	-5,5	0	0	benign	0,23	neutral	0,2	neutral	2,22	neutral	-2,31	neutral	-1,7	low_impact	1,79	neutral	0,62	neutral	0,54	deleterious	2,09	16,77	0,06	0,35	disease	0,88	neutral	0,41	neutral	0,36	disease	0,66	3	neutral	0,76	deleterious	0,49	neutral	-6	deleterious	0,58	medium_impact	-0,23	medium_impact	-0,14	medium_impact	0,65	0,36	0,8	26,36	24,05	N	0,37	N	0,72	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12122	12122	A	T	MI.19194	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1363	455	T	S	Acc/Tcc	-5,5	0	0	benign	0,05	neutral	0,83	neutral	2,3	neutral	-0,59	neutral	-0,57	neutral_impact	-0,24	neutral	0,67	neutral	0,89	deleterious	0,5	7,4	0,4	0,5	disease	0,63	neutral	0,03	neutral	0,15	neutral	0,33	3	neutral	0,09	deleterious	0,89	neutral	-6	neutral	0,2	medium_impact	0,48	medium_impact	0,59	low_impact	-1,36	0,5	0,8	26,36	24,05	N	0,4	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12122	12122	A	G	MI.19195	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1363	455	T	A	Acc/Gcc	-5,5	0	0	benign	0	neutral	0,5	neutral	2,32	neutral	-0,17	neutral	-0,36	low_impact	0,98	neutral	0,75	neutral	0,82	deleterious	1,87	15,41	0,36	0,5	disease	0,67	neutral	0,08	neutral	0,36	neutral	0,38	2	neutral	0,5	deleterious	0,75	neutral	-6	neutral	0,17	high_impact	2,1	medium_impact	0,2	medium_impact	-0,16	0,52	0,8	26,36	24,05	N	0,43	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12123	12123	C	T	MI.19196	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1364	455	T	I	aCc/aTc	-0,43	0	0	benign	0,03	neutral	0,44	neutral	2,32	neutral	-0,35	neutral	1,09	neutral_impact	0,2	neutral	0,76	neutral	0,61	deleterious	2,38	18,66	0,16	0,45	disease	0,71	neutral	0,18	neutral	0,38	neutral	0,47	1	neutral	0,53	deleterious	0,71	neutral	-6	neutral	0,33	medium_impact	0,7	medium_impact	0,14	medium_impact	-0,93	0,62	0,8	26,36	24,05	N	0,37	N	0,23	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12123	12123	C	A	MI.19197	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1364	455	T	N	aCc/aAc	-0,43	0	0	benign	0,23	neutral	0,3	neutral	2,25	neutral	-1,34	neutral	-1,58	low_impact	1,79	neutral	0,71	neutral	0,61	deleterious	2,16	17,27	0,35	0,5	disease	0,8	neutral	0,22	neutral	0,38	disease	0,51	0	neutral	0,64	deleterious	0,54	neutral	-6	neutral	0,43	medium_impact	-0,23	medium_impact	0	medium_impact	0,65	0,49	0,8	26,36	24,05	N	0,4	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12123	12123	C	G	MI.19198	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1364	455	T	S	aCc/aGc	-0,43	0	0	benign	0,05	neutral	0,83	neutral	2,3	neutral	-0,59	neutral	-0,57	neutral_impact	-0,24	neutral	0,67	neutral	0,89	deleterious	0,68	8,69	0,4	0,5	disease	0,63	neutral	0,03	neutral	0,15	neutral	0,33	3	neutral	0,09	deleterious	0,89	neutral	-6	neutral	0,2	medium_impact	0,48	medium_impact	0,59	low_impact	-1,36	0,5	0,8	26,36	24,05	N	0,4	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12125	12125	G	C	MI.19199	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1366	456	G	R	Ggg/Cgg	-1,58	0	0	probably_damaging	1	neutral	0,11	neutral	2,26	neutral	-0,24	deleterious	-6,39	medium_impact	3,08	neutral	0,68	neutral	0,38	deleterious	4,3	24	0,17	0,45	neutral	0,38	disease	0,58	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,76	low_impact	-3,54	medium_impact	-0,31	medium_impact	1,92	0,8	0,85	NA	NA	N	0,38	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8617	8617	A	C	MI.192	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	91	31	I	L	Atc/Ctc	-2,65	0	0	benign	0,01	neutral	0,81	neutral	4,47	neutral	0,37	neutral	-0,18	neutral_impact	-0,26	neutral	0,87	neutral	0,93	deleterious	0,17	4,32	0,44	0,65	neutral	0,35	neutral	0,28	neutral	0,13	neutral	0,46	1	neutral	0,16	deleterious	0,9	neutral	-6	neutral	0,15	medium_impact	1,14	medium_impact	0,65	low_impact	-1,32	0,4	0,9	28,32	22,32	N	0,36	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5923	5923	T	C	MI.1920	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	20	7	L	P	cTa/cCa	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	-1,01	deleterious	-4,29	neutral	-0,86	medium_impact	3,4	damaging	0,53	damaging	0,11	deleterious	3,85	23,4	0,15	0,55	disease	0,75	disease	0,79	disease	0,6	disease	0,71	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,04	0,41	0,9	7,99	10,87	N	0,3	N	0,86	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12125	12125	G	T	MI.19200	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1366	456	G	W	Ggg/Tgg	-1,58	0	0	probably_damaging	1	neutral	0,06	neutral	2,19	deleterious	-3,39	deleterious	-5,97	medium_impact	3,43	neutral	0,67	neutral	0,35	deleterious	4,75	24,7	0,12	0,4	disease	0,87	disease	0,58	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,81	low_impact	-3,54	medium_impact	-0,47	high_impact	2,27	0,11	0,8	NA	NA	N	0,34	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12126	12126	G	C	MI.19201	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1367	456	G	A	gGg/gCg	5,32	1	0	probably_damaging	1	neutral	0,16	neutral	2,31	neutral	0,35	deleterious	-4,81	medium_impact	3,43	neutral	0,72	neutral	0,51	deleterious	3,48	23,1	0,33	0,5	neutral	0,42	neutral	0,29	disease	0,52	neutral	0,42	2	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,72	low_impact	-3,54	medium_impact	-0,2	high_impact	2,27	0,46	0,8	NA	NA	P	0,68	P	0,76	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12126	12126	G	A	MI.19202	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1367	456	G	E	gGg/gAg	5,32	1	0	probably_damaging	1	neutral	0,11	neutral	2,31	neutral	0,51	deleterious	-6,45	medium_impact	3,08	neutral	0,71	neutral	0,41	deleterious	4,2	23,9	0,2	0,45	disease	0,52	disease	0,56	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,78	low_impact	-3,54	medium_impact	-0,31	medium_impact	1,92	0,39	0,8	NA	NA	P	0,62	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12126	12126	G	T	MI.19203	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1367	456	G	V	gGg/gTg	5,32	1	0	probably_damaging	1	neutral	0,19	neutral	2,26	neutral	-0,46	deleterious	-6,29	medium_impact	3,43	neutral	0,69	neutral	0,45	deleterious	4,11	23,7	0,07	0,35	neutral	0,41	disease	0,55	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,75	low_impact	-3,54	medium_impact	-0,15	high_impact	2,27	0,09	0,8	NA	NA	P	0,63	P	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12128	12128	T	C	MI.19204	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1369	457	F	L	Ttt/Ctt	-20	0	0	benign	0	neutral	0,07	neutral	2,43	neutral	0,82	neutral	-0,02	neutral_impact	0,31	neutral	0,86	neutral	0,96	deleterious	0,87	9,92	0,32	0,5	NA	NA	neutral	0,07	neutral	0,26	neutral	0,21	6	neutral	0,93	deleterious	0,54	neutral	-6	neutral	0,08	high_impact	2,1	medium_impact	-0,43	medium_impact	-0,82	0,52	0,8	29,41	29,87	P	0,54	P	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12128	12128	T	A	MI.19205	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1369	457	F	I	Ttt/Att	-20	0	0	benign	0,09	neutral	0,06	neutral	2,33	neutral	-0,17	neutral	-0,38	low_impact	1,14	neutral	0,78	neutral	0,98	neutral	1,68	14,31	0,32	0,5	NA	NA	neutral	0,1	neutral	0,31	neutral	0,23	6	neutral	0,93	deleterious	0,49	neutral	-6	neutral	0,12	medium_impact	0,23	medium_impact	-0,47	medium_impact	0	0,45	0,8	29,41	29,87	N	0,46	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12128	12128	T	G	MI.19206	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1369	457	F	V	Ttt/Gtt	-20	0	0	benign	0,15	deleterious	0	neutral	2,33	neutral	-0,11	neutral	-0,31	low_impact	1,63	neutral	0,81	neutral	0,91	deleterious	2,43	19,04	0,25	0,45	NA	NA	neutral	0,19	disease	0,6	neutral	0,3	4	deleterious	1	neutral	0,43	neutral	-2	neutral	0,12	medium_impact	-0,01	low_impact	-1,48	medium_impact	0,49	0,44	0,8	29,41	29,87	N	0,43	N	0,39	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12129	12129	T	G	MI.19207	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1370	457	F	C	tTt/tGt	-3,65	0	0	possibly_damaging	0,86	deleterious	0	neutral	2,21	neutral	-2,98	neutral	-0,93	medium_impact	2,17	neutral	0,67	neutral	0,67	deleterious	3,99	23,6	0,12	0,4	NA	NA	neutral	0,26	disease	0,61	neutral	0,29	4	deleterious	1	neutral	0,07	deleterious	4	deleterious	0,55	low_impact	-1,46	low_impact	-1,48	medium_impact	1,02	0,23	0,8	29,41	29,87	N	0,46	N	0,58	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12129	12129	T	A	MI.19208	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1370	457	F	Y	tTt/tAt	-3,65	0	0	benign	0,43	deleterious	0	neutral	2,28	neutral	-0,55	neutral	0,24	low_impact	1,38	neutral	0,82	neutral	0,92	deleterious	2,56	19,83	0,24	0,45	NA	NA	neutral	0,1	neutral	0,28	neutral	0,22	6	deleterious	1	neutral	0,29	neutral	-2	neutral	0,25	medium_impact	-0,6	low_impact	-1,48	medium_impact	0,24	0,43	0,8	29,41	29,87	N	0,5	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12129	12129	T	C	MI.19209	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1370	457	F	S	tTt/tCt	-3,65	0	0	possibly_damaging	0,56	deleterious	0	neutral	2,27	neutral	-1,12	neutral	-0,66	low_impact	1,49	neutral	0,7	neutral	0,72	deleterious	2,68	20,7	0,13	0,4	NA	NA	neutral	0,19	disease	0,57	neutral	0,32	4	deleterious	1	neutral	0,22	deleterious	1	neutral	0,3	medium_impact	-0,82	low_impact	-1,48	medium_impact	0,35	0,2	0,8	29,41	29,87	N	0,45	N	0,49	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5923	5923	T	G	MI.1921	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	20	7	L	R	cTa/cGa	-1,49	0	0	probably_damaging	0,99	deleterious	0	neutral	-1,01	deleterious	-3,61	neutral	-0,73	medium_impact	2,94	damaging	0,57	damaging	0,11	deleterious	3,81	23,4	0,17	0,55	disease	0,68	disease	0,84	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,86	low_impact	-2,64	low_impact	-1,48	medium_impact	1,62	0,66	0,9	7,99	10,87	N	0,28	N	0,88	disease_causing	0,85	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12130	12130	T	A	MI.19210	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1371	457	F	L	ttT/ttA	-1,35	0	0	benign	0	neutral	0,07	neutral	2,43	neutral	0,82	neutral	-0,02	neutral_impact	0,31	neutral	0,86	neutral	0,96	neutral	1,11	11,25	0,32	0,5	NA	NA	neutral	0,07	neutral	0,26	neutral	0,21	6	neutral	0,93	deleterious	0,54	neutral	-6	neutral	0,08	high_impact	2,1	medium_impact	-0,43	medium_impact	-0,82	0,52	0,8	29,41	29,87	P	0,54	P	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12130	12130	T	G	MI.19211	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1371	457	F	L	ttT/ttG	-1,35	0	0	benign	0	neutral	0,07	neutral	2,43	neutral	0,82	neutral	-0,02	neutral_impact	0,31	neutral	0,86	neutral	0,96	neutral	0,99	10,62	0,32	0,5	NA	NA	neutral	0,07	neutral	0,26	neutral	0,21	6	neutral	0,93	deleterious	0,54	neutral	-6	neutral	0,08	high_impact	2,1	medium_impact	-0,43	medium_impact	-0,82	0,52	0,8	29,41	29,87	P	0,54	P	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12131	12131	T	A	MI.19212	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1372	458	S	T	Tcc/Acc	-10,33	0	0	benign	0	neutral	0,74	neutral	2,28	neutral	-0,6	neutral	1,59	neutral_impact	-1,34	neutral	0,9	neutral	0,99	neutral	-0,75	0,05	0,45	0,55	NA	NA	neutral	0,01	neutral	0,15	neutral	0,11	8	neutral	0,26	deleterious	0,87	neutral	-6	neutral	0,03	high_impact	2,1	medium_impact	0,46	low_impact	-2,45	0,41	0,8	26,14	26,85	N	0,38	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12131	12131	T	G	MI.19213	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1372	458	S	A	Tcc/Gcc	-10,33	0	0	benign	0	neutral	0,4	neutral	2,33	neutral	0	neutral	-0,26	low_impact	1,15	neutral	0,86	neutral	0,88	deleterious	0,68	8,66	0,46	0,55	NA	NA	neutral	0,02	neutral	0,24	neutral	0,11	8	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,04	high_impact	2,1	medium_impact	0,1	medium_impact	0,01	0,2	0,8	26,14	26,85	N	0,47	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12131	12131	T	C	MI.19214	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1372	458	S	P	Tcc/Ccc	-10,33	0	0	benign	0,05	neutral	0,29	neutral	2,2	neutral	-2,14	neutral	-0,72	low_impact	1,15	neutral	0,77	neutral	0,7	deleterious	2,18	17,36	0,22	0,45	NA	NA	neutral	0,25	neutral	0,28	neutral	0,17	7	neutral	0,69	deleterious	0,62	neutral	-6	neutral	0,12	medium_impact	0,48	medium_impact	-0,02	medium_impact	0,01	0,18	0,8	26,14	26,85	N	0,49	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12132	12132	C	T	MI.19215	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1373	458	S	F	tCc/tTc	-2,04	0	0	benign	0,11	neutral	0,13	neutral	2,2	neutral	-2,23	neutral	-0,7	neutral_impact	-0,84	neutral	0,82	neutral	0,72	deleterious	2,46	19,22	0,22	0,45	NA	NA	neutral	0,13	neutral	0,35	neutral	0,15	7	neutral	0,85	deleterious	0,51	neutral	-6	neutral	0,14	medium_impact	0,14	medium_impact	-0,26	low_impact	-1,96	0,13	0,8	26,14	26,85	N	0,41	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12132	12132	C	A	MI.19216	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1373	458	S	Y	tCc/tAc	-2,04	0	0	benign	0,17	neutral	0,11	neutral	2,19	neutral	-2,41	neutral	-0,26	neutral_impact	0,46	neutral	0,77	neutral	0,74	deleterious	2,32	18,28	0,23	0,45	NA	NA	neutral	0,15	neutral	0,34	neutral	0,18	6	neutral	0,87	deleterious	0,47	neutral	-6	neutral	0,14	medium_impact	-0,07	medium_impact	-0,31	medium_impact	-0,67	0,15	0,8	26,14	26,85	N	0,46	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12132	12132	C	G	MI.19217	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1373	458	S	C	tCc/tGc	-2,04	0	0	benign	0,22	neutral	1	neutral	2,18	neutral	-2,76	neutral	-0,02	neutral_impact	0,26	neutral	0,8	neutral	0,89	deleterious	0,78	9,33	0,23	0,45	NA	NA	neutral	0,04	neutral	0,25	neutral	0,13	8	neutral	0,22	deleterious	0,89	neutral	-6	neutral	0,13	medium_impact	-0,2	high_impact	1,88	medium_impact	-0,87	0,18	0,8	26,14	26,85	N	0,28	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12134	12134	T	C	MI.19218	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1375	459	S	P	Tct/Cct	-4,58	0	0	benign	0,34	deleterious	0,04	neutral	2,23	neutral	-1,38	neutral	-0,15	neutral_impact	0,24	neutral	0,63	neutral	0,69	deleterious	2,42	18,92	0,25	0,45	NA	NA	neutral	0,31	disease	0,55	neutral	0,26	5	neutral	0,95	neutral	0,35	neutral	-2	deleterious	0,5	medium_impact	-0,45	medium_impact	-0,57	medium_impact	-0,89	0,29	0,8	NA	NA	N	0,38	N	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12134	12134	T	G	MI.19219	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1375	459	S	A	Tct/Gct	-4,58	0	0	benign	0	neutral	1	neutral	2,33	neutral	0,17	neutral	0,01	low_impact	1,29	neutral	0,87	neutral	0,96	deleterious	-0,01	2,53	0,49	0,55	NA	NA	neutral	0,01	neutral	0,23	neutral	0,12	8	neutral	0	deleterious	1	neutral	-6	neutral	0,16	high_impact	2,1	high_impact	1,88	medium_impact	0,15	0,34	0,8	NA	NA	N	0,36	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5925	5925	T	A	MI.1922	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	22	8	F	I	Ttc/Atc	-2,42	0	0	benign	0,3	deleterious	0,01	neutral	-1,04	neutral	-1,23	neutral	-0,64	medium_impact	2,96	neutral	0,66	neutral	0,54	deleterious	4,22	23,9	0,23	0,55	neutral	0,27	disease	0,77	disease	0,61	disease	0,7	4	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,45	medium_impact	-0,41	medium_impact	-0,92	medium_impact	1,63	0,43	0,9	5,85	21,28	N	0,39	N	0,87	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12134	12134	T	A	MI.19220	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1375	459	S	T	Tct/Act	-4,58	0	0	benign	0,01	neutral	0,5	neutral	2,28	neutral	-0,49	neutral	0,1	neutral_impact	0,56	neutral	0,9	neutral	0,81	deleterious	0,7	8,82	0,49	0,55	NA	NA	neutral	0,06	neutral	0,26	neutral	0,12	8	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,19	medium_impact	1,16	medium_impact	0,2	medium_impact	-0,57	0,66	0,8	NA	NA	N	0,47	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12135	12135	C	G	MI.19221	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1376	459	S	C	tCt/tGt	-0,43	0	0,01	possibly_damaging	0,63	neutral	0,07	neutral	2,21	neutral	-2,25	neutral	0,13	low_impact	1,84	neutral	0,71	neutral	0,74	deleterious	3,54	23,1	0,24	0,45	NA	NA	neutral	0,18	neutral	0,36	neutral	0,23	5	neutral	0,93	neutral	0,22	neutral	-3	deleterious	0,73	medium_impact	-0,94	medium_impact	-0,43	medium_impact	0,69	0,26	0,8	NA	NA	P	0,53	P	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12135	12135	C	A	MI.19222	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1376	459	S	Y	tCt/tAt	-0,43	0	0,01	possibly_damaging	0,63	deleterious	0,01	neutral	2,24	neutral	-1,34	neutral	3,76	neutral_impact	0,6	neutral	0,74	neutral	0,78	deleterious	3,91	23,5	0,25	0,45	NA	NA	neutral	0,23	disease	0,57	neutral	0,27	5	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,7	medium_impact	-0,94	medium_impact	-0,92	medium_impact	-0,53	0,25	0,8	NA	NA	N	0,44	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12135	12135	C	T	MI.19223	MT-ND4	I	ENSG00000198886	ENSP00000354961	ENST00000361381	NU4M_HUMAN	P03905	4538	YP_003024035.1	1376	459	S	F	tCt/tTt	-0,43	0	0,01	possibly_damaging	0,54	deleterious	0,01	neutral	2,24	neutral	-1,1	neutral	2,62	low_impact	0,87	neutral	0,7	neutral	0,74	deleterious	3,93	23,5	0,23	0,45	NA	NA	neutral	0,26	disease	0,57	neutral	0,26	5	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,57	medium_impact	-0,78	medium_impact	-0,92	medium_impact	-0,27	0,17	0,8	NA	NA	N	0,44	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12337	12337	A	T	MI.19224	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1	1	M	L	Ata/Tta	0,95	0,99	0	unknown	NA	deleterious	0	neutral	3,94	neutral	1,02	neutral	-1,98	NA	NA	neutral	0,83	neutral	0,52	deleterious	0,25	5,24	0,29	0,45	NA	NA	neutral	0,09	neutral	0,3	neutral	0,11	8	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,44	NA	NA	NA	NA	NA	NA	0,49	0,8	17,08	13,19	P	0,51	P	0,57	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12337	12337	A	C	MI.19225	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1	1	M	L	Ata/Cta	0,95	0,99	0	unknown	NA	deleterious	0	neutral	3,94	neutral	1,02	neutral	-1,98	NA	NA	neutral	0,83	neutral	0,52	deleterious	0,17	4,32	0,29	0,45	NA	NA	neutral	0,09	neutral	0,3	neutral	0,11	8	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,44	NA	NA	NA	NA	NA	NA	0,49	0,8	17,08	13,19	P	0,51	P	0,57	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12337	12337	A	G	MI.19226	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1	1	M	V	Ata/Gta	0,95	0,99	0	unknown	NA	deleterious	0	neutral	3,87	neutral	0,46	deleterious	-2,57	NA	NA	neutral	0,82	neutral	0,35	deleterious	0,86	9,83	0,42	0,5	NA	NA	neutral	0,1	neutral	0,48	neutral	0,13	7	deleterious	1	deleterious	0,5	deleterious	2	neutral	0,43	NA	NA	NA	NA	NA	NA	0,39	0,8	17,08	13,19	N	0,47	N	0,55	NA	NA	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12338	12338	T	C	MI.19227	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	2	1	M	T	aTa/aCa	2,33	0,99	0,02	unknown	NA	deleterious	0	neutral	3,78	neutral	-0,75	deleterious	-3,8	NA	NA	neutral	0,75	damaging	0,27	neutral	1,1	11,23	0,38	0,5	NA	NA	neutral	0,19	neutral	0,32	neutral	0,27	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,49	NA	NA	NA	NA	NA	NA	0,28	0,8	17,08	13,19	P	0,61	P	0,78	NA	NA	0,07	rs201863060	Pathogenic	Leber's_optic_atrophy	RCV000022893.4	MedGen:OMIM:SNOMED_CT	.	.	.	.	T12338C	DEAF 1555 increased penetrance/LHON	+	-	Conflicting reports	7
chrM	12338	12338	T	A	MI.19228	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	2	1	M	K	aTa/aAa	2,33	0,99	0,02	unknown	NA	deleterious	0	neutral	3,79	neutral	-0,7	deleterious	-3,91	NA	NA	neutral	0,74	neutral	0,29	deleterious	2,17	17,3	0,21	0,45	NA	NA	neutral	0,24	disease	0,54	neutral	0,26	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,52	NA	NA	NA	NA	NA	NA	0,42	0,8	17,08	13,19	N	0,49	N	0,9	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12339	12339	A	T	MI.19229	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	3	1	M	I	atA/atT	1,64	0,96	0	unknown	NA	deleterious	0	neutral	3,86	neutral	0,35	deleterious	-2,56	NA	NA	neutral	0,91	neutral	0,51	deleterious	0,45	7,04	0,35	0,5	NA	NA	neutral	0,11	neutral	0,28	neutral	0,15	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,44	NA	NA	NA	NA	NA	NA	0,52	0,8	17,08	13,19	P	0,5	N	0,18	NA	NA	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5925	5925	T	C	MI.1923	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	22	8	F	L	Ttc/Ctc	-2,42	0	0	benign	0,21	deleterious	0,03	neutral	-1,01	neutral	-0,57	neutral	-0,61	medium_impact	2,06	neutral	0,64	neutral	0,51	deleterious	3,79	23,4	0,29	0,55	neutral	0,24	disease	0,64	neutral	0,38	neutral	0,48	0	neutral	0,97	neutral	0,41	deleterious	1	neutral	0,29	medium_impact	-0,22	medium_impact	-0,65	medium_impact	0,8	0,48	0,9	5,85	21,28	N	0,45	N	0,81	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12339	12339	A	C	MI.19230	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	3	1	M	I	atA/atC	1,64	0,96	0	unknown	NA	deleterious	0	neutral	3,86	neutral	0,35	deleterious	-2,56	NA	NA	neutral	0,91	neutral	0,51	deleterious	0,42	6,76	0,35	0,5	NA	NA	neutral	0,11	neutral	0,28	neutral	0,15	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,44	NA	NA	NA	NA	NA	NA	0,52	0,8	17,08	13,19	P	0,5	N	0,18	NA	NA	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12340	12340	A	C	MI.19231	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	4	2	T	P	Acc/Ccc	-0,2	0	0	unknown	NA	neutral	0,21	neutral	3,71	neutral	-1,87	neutral	-1,42	low_impact	0,9	neutral	0,66	neutral	0,72	deleterious	0,5	7,45	0,29	0,45	NA	NA	neutral	0,25	neutral	0,23	neutral	0,25	5	neutral	0,79	deleterious	0,61	neutral	-4	neutral	0,23	high_impact	2,1	medium_impact	-0,09	medium_impact	-0,38	0,55	0,8	28,03	39,33	N	0,46	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12340	12340	A	T	MI.19232	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	4	2	T	S	Acc/Tcc	-0,2	0	0	unknown	NA	neutral	0,41	neutral	3,8	neutral	-0,01	neutral	0,64	low_impact	0,9	neutral	0,81	neutral	0,84	deleterious	0,17	4,39	0,4	0,5	NA	NA	neutral	0,05	neutral	0,08	neutral	0,08	8	neutral	0,59	deleterious	0,71	neutral	-4	neutral	0,12	high_impact	2,1	medium_impact	0,15	medium_impact	-0,38	0,66	0,8	28,03	39,33	N	0,5	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12340	12340	A	G	MI.19233	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	4	2	T	A	Acc/Gcc	-0,2	0	0	unknown	NA	neutral	0,51	neutral	3,83	neutral	0,2	neutral	-1,46	low_impact	0,9	neutral	0,85	neutral	0,85	deleterious	0,36	6,25	0,51	0,6	NA	NA	neutral	0,04	neutral	0,11	neutral	0,08	8	neutral	0,49	deleterious	0,76	neutral	-4	neutral	0,11	high_impact	2,1	medium_impact	0,24	medium_impact	-0,38	0,34	0,8	28,03	39,33	N	0,4	N	0,4	polymorphism	1	0,03	rs28490236	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12341	12341	C	G	MI.19234	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	5	2	T	S	aCc/aGc	-0,2	0	0	unknown	NA	neutral	0,41	neutral	3,8	neutral	-0,01	neutral	0,64	low_impact	0,9	neutral	0,81	neutral	0,84	deleterious	0,37	6,35	0,4	0,5	NA	NA	neutral	0,05	neutral	0,08	neutral	0,08	8	neutral	0,59	deleterious	0,71	neutral	-4	neutral	0,12	high_impact	2,1	medium_impact	0,15	medium_impact	-0,38	0,66	0,8	28,03	39,33	N	0,51	P	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12341	12341	C	A	MI.19235	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	5	2	T	N	aCc/aAc	-0,2	0	0	unknown	NA	neutral	0,35	neutral	3,75	neutral	-0,74	neutral	4,29	neutral_impact	0,2	neutral	0,8	neutral	0,97	neutral	-0,84	0,04	0,5	0,6	NA	NA	neutral	0,02	neutral	0,07	neutral	0,13	7	neutral	0,65	deleterious	0,68	neutral	-4	neutral	0,1	high_impact	2,1	medium_impact	0,08	low_impact	-1,02	0,56	0,8	28,03	39,33	N	0,5	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12341	12341	C	T	MI.19236	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	5	2	T	I	aCc/aTc	-0,2	0	0	unknown	NA	neutral	0,4	neutral	3,76	neutral	-1,04	neutral	-2,12	neutral_impact	-0,2	neutral	0,86	neutral	0,87	deleterious	0,8	9,48	0,32	0,5	NA	NA	neutral	0,12	neutral	0,28	neutral	0,14	7	neutral	0,6	deleterious	0,7	neutral	-4	neutral	0,16	high_impact	2,1	medium_impact	0,14	low_impact	-1,39	0,3	0,8	28,03	39,33	N	0,37	N	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12343	12343	A	T	MI.19237	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	7	3	M	L	Atg/Ttg	-5,5	0	0	unknown	NA	neutral	1	neutral	3,93	neutral	1,03	neutral	0,17	low_impact	0,88	neutral	0,86	neutral	0,93	neutral	-0,25	0,85	0,35	0,5	NA	NA	neutral	0,05	neutral	0,23	neutral	0,12	8	neutral	0	deleterious	1	neutral	-4	neutral	0,15	high_impact	2,1	high_impact	1,89	medium_impact	-0,4	0,43	0,8	17,91	17,43	N	0,34	N	0,64	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12343	12343	A	G	MI.19238	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	7	3	M	V	Atg/Gtg	-5,5	0	0	unknown	NA	neutral	0,49	neutral	3,83	neutral	0,92	neutral	-1,1	low_impact	1,73	neutral	0,77	neutral	0,57	deleterious	-0,03	2,34	0,38	0,5	NA	NA	neutral	0,15	neutral	0,36	neutral	0,18	6	neutral	0,51	deleterious	0,75	neutral	-4	neutral	0,23	high_impact	2,1	medium_impact	0,22	medium_impact	0,38	0,37	0,8	17,91	17,43	N	0,31	N	0,75	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12343	12343	A	C	MI.19239	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	7	3	M	L	Atg/Ctg	-5,5	0	0	unknown	NA	neutral	1	neutral	3,93	neutral	1,03	neutral	0,17	low_impact	0,88	neutral	0,86	neutral	0,93	neutral	-0,34	0,53	0,35	0,5	NA	NA	neutral	0,05	neutral	0,23	neutral	0,12	8	neutral	0	deleterious	1	neutral	-4	neutral	0,15	high_impact	2,1	high_impact	1,89	medium_impact	-0,4	0,43	0,8	17,91	17,43	N	0,34	N	0,64	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5925	5925	T	G	MI.1924	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	22	8	F	V	Ttc/Gtc	-2,42	0	0	possibly_damaging	0,49	deleterious	0,01	neutral	-1,04	neutral	-0,88	neutral	-0,75	medium_impact	2,53	neutral	0,63	neutral	0,48	deleterious	3,87	23,5	0,26	0,55	neutral	0,26	disease	0,79	disease	0,62	disease	0,71	4	deleterious	0,99	neutral	0,26	deleterious	4	deleterious	0,45	medium_impact	-0,74	medium_impact	-0,92	medium_impact	1,24	0,41	0,9	5,85	21,28	N	0,37	N	0,84	polymorphism	0,97	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12344	12344	T	C	MI.19240	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	8	3	M	T	aTg/aCg	-8,95	0	0	unknown	NA	neutral	0,49	neutral	3,74	neutral	0,02	neutral	-2,39	medium_impact	2,07	damaging	0,59	neutral	0,4	deleterious	0,11	3,66	0,42	0,55	NA	NA	neutral	0,22	neutral	0,38	neutral	0,21	6	neutral	0,51	deleterious	0,75	neutral	-1	neutral	0,27	high_impact	2,1	medium_impact	0,22	medium_impact	0,69	0,28	0,8	17,91	17,43	N	0,34	N	0,79	polymorphism	1	0,04	.	.	.	.	.	.	COSM488731	.	.	.	.	.	.	.	.
chrM	12344	12344	T	A	MI.19241	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	8	3	M	K	aTg/aAg	-8,95	0	0	unknown	NA	neutral	0,35	neutral	3,74	neutral	0,19	deleterious	-3,34	medium_impact	2,07	neutral	0,62	neutral	0,4	deleterious	2,29	18,13	0,26	0,45	NA	NA	neutral	0,32	disease	0,63	neutral	0,29	4	neutral	0,65	deleterious	0,68	neutral	-1	neutral	0,34	high_impact	2,1	medium_impact	0,08	medium_impact	0,69	0,46	0,8	17,91	17,43	N	0,34	N	0,91	polymorphism	1	0,1	.	.	.	.	.	breast tumor	.	.	.	.	.	.	.	.	.
chrM	12345	12345	G	C	MI.19242	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	9	3	M	I	atG/atC	-0,66	0	0	unknown	NA	neutral	0,58	neutral	3,82	neutral	0,73	neutral	-0,74	medium_impact	2,07	neutral	0,76	neutral	0,83	deleterious	0,72	8,94	0,36	0,5	NA	NA	neutral	0,16	neutral	0,33	neutral	0,19	6	neutral	0,42	deleterious	0,79	neutral	-1	neutral	0,23	high_impact	2,1	medium_impact	0,31	medium_impact	0,69	0,49	0,8	17,91	17,43	N	0,33	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12345	12345	G	T	MI.19243	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	9	3	M	I	atG/atT	-0,66	0	0	unknown	NA	neutral	0,58	neutral	3,82	neutral	0,73	neutral	-0,74	medium_impact	2,07	neutral	0,76	neutral	0,83	deleterious	0,83	9,63	0,36	0,5	NA	NA	neutral	0,16	neutral	0,33	neutral	0,19	6	neutral	0,42	deleterious	0,79	neutral	-1	neutral	0,23	high_impact	2,1	medium_impact	0,31	medium_impact	0,69	0,49	0,8	17,91	17,43	N	0,34	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12346	12346	C	A	MI.19244	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	10	4	H	N	Cac/Aac	0,03	0	0	unknown	NA	neutral	0,4	neutral	3,83	neutral	0,23	neutral	-0,3	low_impact	0,8	neutral	0,82	neutral	0,89	deleterious	0,71	8,87	0,65	0,7	NA	NA	neutral	0,1	neutral	0,46	neutral	0,13	7	neutral	0,6	deleterious	0,7	neutral	-4	neutral	0,16	high_impact	2,1	medium_impact	0,14	medium_impact	-0,47	0,55	0,8	27,03	26,34	N	0,41	N	0,35	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12346	12346	C	T	MI.19245	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	10	4	H	Y	Cac/Tac	0,03	0	0	unknown	NA	neutral	1	neutral	3,81	neutral	0,8	neutral	1,4	neutral_impact	-0,94	neutral	0,94	neutral	0,86	deleterious	0,25	5,21	0,52	0,6	NA	NA	neutral	0,11	neutral	0,25	neutral	0,13	7	neutral	0	deleterious	1	neutral	-4	neutral	0,18	high_impact	2,1	high_impact	1,89	low_impact	-2,06	0,39	0,8	27,03	26,34	N	0,21	N	0,03	polymorphism	1	0	rs200279497	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12346	12346	C	G	MI.19246	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	10	4	H	D	Cac/Gac	0,03	0	0	unknown	NA	neutral	0,2	neutral	3,81	neutral	0,04	neutral	-1,49	low_impact	0,8	neutral	0,76	neutral	0,76	neutral	1,01	10,7	0,32	0,5	NA	NA	neutral	0,21	disease	0,55	neutral	0,25	5	neutral	0,8	deleterious	0,6	neutral	-4	neutral	0,17	high_impact	2,1	medium_impact	-0,1	medium_impact	-0,47	0,58	0,8	27,03	26,34	N	0,38	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12347	12347	A	T	MI.19247	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	11	4	H	L	cAc/cTc	-3,65	0	0	unknown	NA	neutral	0,88	neutral	3,87	neutral	1,25	neutral	1	neutral_impact	-0,44	neutral	0,9	neutral	0,92	deleterious	0,44	6,96	0,28	0,45	NA	NA	neutral	0,17	neutral	0,27	neutral	0,15	7	neutral	0,12	deleterious	0,94	neutral	-4	neutral	0,15	high_impact	2,1	medium_impact	0,71	low_impact	-1,61	0,42	0,8	27,03	26,34	N	0,31	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12347	12347	A	G	MI.19248	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	11	4	H	R	cAc/cGc	-3,65	0	0	unknown	NA	neutral	0,34	neutral	3,83	neutral	0,57	neutral	-1,18	low_impact	0,8	neutral	0,78	neutral	0,78	deleterious	0,09	3,49	0,52	0,6	NA	NA	neutral	0,21	neutral	0,46	neutral	0,22	6	neutral	0,66	deleterious	0,67	neutral	-4	neutral	0,22	high_impact	2,1	medium_impact	0,07	medium_impact	-0,47	0,28	0,8	27,03	26,34	N	0,34	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12347	12347	A	C	MI.19249	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	11	4	H	P	cAc/cCc	-3,65	0	0	unknown	NA	neutral	0,28	neutral	3,78	neutral	-0,83	neutral	-1,86	neutral_impact	0,11	neutral	0,7	neutral	0,71	deleterious	0,43	6,87	0,31	0,45	NA	NA	neutral	0,35	disease	0,63	neutral	0,29	4	neutral	0,72	deleterious	0,64	neutral	-4	neutral	0,29	high_impact	2,1	medium_impact	0,01	low_impact	-1,1	0,41	0,8	27,03	26,34	N	0,37	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5926	5926	T	G	MI.1925	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	23	8	F	C	tTc/tGc	7,53	1	0	probably_damaging	0,96	neutral	0,06	neutral	-1,06	deleterious	-3,5	neutral	-0,84	medium_impact	2,88	neutral	0,64	neutral	0,49	deleterious	3,88	23,5	0,21	0,55	disease	0,63	disease	0,81	neutral	0,38	disease	0,61	2	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,77	low_impact	-2,06	medium_impact	-0,47	medium_impact	1,56	0,22	0,9	5,85	21,28	P	0,54	P	0,91	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12348	12348	C	A	MI.19250	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	12	4	H	Q	caC/caA	0,03	0	0	unknown	NA	neutral	0,28	neutral	3,83	neutral	0,57	neutral	-1,03	low_impact	0,8	neutral	0,78	neutral	0,82	neutral	0,95	10,39	0,6	0,65	NA	NA	neutral	0,12	neutral	0,46	neutral	0,17	7	neutral	0,72	deleterious	0,64	neutral	-4	neutral	0,15	high_impact	2,1	medium_impact	0,01	medium_impact	-0,47	0,55	0,8	27,03	26,34	N	0,41	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12348	12348	C	G	MI.19251	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	12	4	H	Q	caC/caG	0,03	0	0	unknown	NA	neutral	0,28	neutral	3,83	neutral	0,57	neutral	-1,03	low_impact	0,8	neutral	0,78	neutral	0,82	deleterious	0,61	8,23	0,6	0,65	NA	NA	neutral	0,12	neutral	0,46	neutral	0,17	7	neutral	0,72	deleterious	0,64	neutral	-4	neutral	0,15	high_impact	2,1	medium_impact	0,01	medium_impact	-0,47	0,55	0,8	27,03	26,34	N	0,42	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12349	12349	A	C	MI.19252	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	13	5	T	P	Act/Cct	-5,78	0	0	unknown	NA	neutral	0,31	neutral	3,69	neutral	-1,53	neutral	-1,39	medium_impact	2,02	neutral	0,82	neutral	0,83	deleterious	0,55	7,77	0,29	0,45	NA	NA	neutral	0,21	neutral	0,4	neutral	0,19	6	neutral	0,69	deleterious	0,66	neutral	-1	neutral	0,22	high_impact	2,1	medium_impact	0,04	medium_impact	0,64	0,68	0,85	27,03	13,76	N	0,4	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12349	12349	A	T	MI.19253	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	13	5	T	S	Act/Tct	-5,78	0	0	unknown	NA	neutral	0,55	neutral	3,8	neutral	-0,08	neutral	-0,1	neutral_impact	0,68	neutral	0,88	neutral	0,97	neutral	-0,9	0,03	0,5	0,6	NA	NA	neutral	0,03	neutral	0,2	neutral	0,13	7	neutral	0,45	deleterious	0,78	neutral	-4	neutral	0,09	high_impact	2,1	medium_impact	0,28	medium_impact	-0,58	0,53	0,8	27,03	13,76	N	0,45	N	0,02	polymorphism	1	0	.	.	.	.	.	.	COSM1155519	.	.	.	.	.	.	.	.
chrM	12349	12349	A	G	MI.19254	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	13	5	T	A	Act/Gct	-5,78	0	0	unknown	NA	neutral	0,48	neutral	3,79	neutral	0,08	neutral	-0,92	low_impact	1,48	neutral	0,89	neutral	0,91	deleterious	0,3	5,68	0,52	0,6	NA	NA	neutral	0,07	neutral	0,45	neutral	0,12	8	neutral	0,52	deleterious	0,74	neutral	-4	neutral	0,13	high_impact	2,1	medium_impact	0,21	medium_impact	0,15	0,43	0,8	27,03	13,76	N	0,47	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12350	12350	C	G	MI.19255	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	14	5	T	S	aCt/aGt	-5,55	0	0	unknown	NA	neutral	0,55	neutral	3,8	neutral	-0,08	neutral	-0,1	neutral_impact	0,68	neutral	0,88	neutral	0,97	neutral	-0,53	0,19	0,5	0,6	NA	NA	neutral	0,03	neutral	0,2	neutral	0,13	7	neutral	0,45	deleterious	0,78	neutral	-4	neutral	0,09	high_impact	2,1	medium_impact	0,28	medium_impact	-0,58	0,53	0,8	27,03	13,76	N	0,43	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12350	12350	C	A	MI.19256	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	14	5	T	N	aCt/aAt	-5,55	0	0	unknown	NA	neutral	0,26	neutral	3,74	neutral	-0,75	neutral	-0,56	low_impact	1,08	neutral	0,88	neutral	0,89	deleterious	0,49	7,37	0,53	0,6	NA	NA	neutral	0,12	neutral	0,25	neutral	0,15	7	neutral	0,74	deleterious	0,63	neutral	-4	neutral	0,16	high_impact	2,1	medium_impact	-0,02	medium_impact	-0,22	0,54	0,8	27,03	13,76	N	0,48	N	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12350	12350	C	T	MI.19257	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	14	5	T	I	aCt/aTt	-5,55	0	0	unknown	NA	neutral	0,67	neutral	3,73	neutral	-0,49	neutral	-1,44	medium_impact	2,37	neutral	0,86	neutral	0,87	neutral	1,04	10,9	0,39	0,5	NA	NA	neutral	0,17	neutral	0,32	neutral	0,17	7	neutral	0,33	deleterious	0,84	neutral	-1	neutral	0,21	high_impact	2,1	medium_impact	0,4	medium_impact	0,96	0,6	0,8	27,03	13,76	N	0,28	N	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12352	12352	A	T	MI.19258	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	16	6	T	S	Act/Tct	-10,83	0	0	unknown	NA	neutral	0,49	neutral	3,79	neutral	-0,17	neutral	0,12	neutral_impact	0,32	neutral	0,9	neutral	0,97	neutral	-1,1	0,01	0,51	0,6	NA	NA	neutral	0,02	neutral	0,3	neutral	0,13	7	neutral	0,51	deleterious	0,75	neutral	-4	neutral	0,08	high_impact	2,1	medium_impact	0,22	medium_impact	-0,91	0,46	0,8	5,31	9,93	N	0,51	P	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12352	12352	A	G	MI.19259	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	16	6	T	A	Act/Gct	-10,83	0	0	unknown	NA	neutral	0,31	neutral	3,77	neutral	-0,02	neutral	-1,28	low_impact	1,59	neutral	0,85	neutral	0,88	neutral	1,79	14,92	0,54	0,6	NA	NA	neutral	0,11	disease	0,7	neutral	0,25	5	neutral	0,69	deleterious	0,66	neutral	-4	neutral	0,14	high_impact	2,1	medium_impact	0,04	medium_impact	0,25	0,34	0,8	5,31	9,93	N	0,43	N	0,31	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5926	5926	T	A	MI.1926	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	23	8	F	Y	tTc/tAc	7,53	1	0	benign	0,01	neutral	0,11	neutral	-0,99	neutral	-2,18	neutral	-0,18	low_impact	1,64	neutral	0,65	neutral	0,8	deleterious	2,86	21,7	0,31	0,55	neutral	0,25	neutral	0,39	neutral	0,31	neutral	0,44	1	neutral	0,89	deleterious	0,55	neutral	-6	neutral	0,17	medium_impact	1,12	medium_impact	-0,31	medium_impact	0,42	0,54	0,9	5,85	21,28	P	0,68	P	0,58	disease_causing	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12352	12352	A	C	MI.19260	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	16	6	T	P	Act/Cct	-10,83	0	0	unknown	NA	neutral	0,18	neutral	3,68	neutral	-2,06	neutral	-2,24	low_impact	1	neutral	0,81	neutral	0,79	deleterious	0,68	8,72	0,3	0,45	NA	NA	neutral	0,42	disease	0,8	disease	0,51	0	neutral	0,82	deleterious	0,59	neutral	-4	neutral	0,27	high_impact	2,1	medium_impact	-0,13	medium_impact	-0,29	0,51	0,8	5,31	9,93	N	0,39	N	0,15	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12353	12353	C	A	MI.19261	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	17	6	T	N	aCt/aAt	-0,5	0	0	unknown	NA	neutral	0,24	neutral	3,71	neutral	-1,09	neutral	-1,55	medium_impact	2,29	neutral	0,78	neutral	0,74	deleterious	1,87	15,41	0,55	0,6	NA	NA	neutral	0,28	disease	0,73	neutral	0,34	3	neutral	0,76	deleterious	0,62	neutral	-1	neutral	0,18	high_impact	2,1	medium_impact	-0,04	medium_impact	0,89	0,57	0,8	5,31	9,93	N	0,36	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12353	12353	C	T	MI.19262	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	17	6	T	I	aCt/aTt	-0,5	0	0	unknown	NA	neutral	0,49	neutral	3,74	neutral	-0,18	neutral	-2,19	medium_impact	2,29	neutral	0,75	neutral	0,76	deleterious	2,2	17,49	0,33	0,5	NA	NA	neutral	0,26	disease	0,69	neutral	0,29	4	neutral	0,51	deleterious	0,75	neutral	-1	neutral	0,19	high_impact	2,1	medium_impact	0,22	medium_impact	0,89	0,5	0,8	5,31	9,93	N	0,37	N	0,8	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12353	12353	C	G	MI.19263	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	17	6	T	S	aCt/aGt	-0,5	0	0	unknown	NA	neutral	0,49	neutral	3,79	neutral	-0,17	neutral	0,12	neutral_impact	0,32	neutral	0,9	neutral	0,97	neutral	-0,92	0,02	0,51	0,6	NA	NA	neutral	0,02	neutral	0,3	neutral	0,13	7	neutral	0,51	deleterious	0,75	neutral	-4	neutral	0,08	high_impact	2,1	medium_impact	0,22	medium_impact	-0,91	0,46	0,8	5,31	9,93	N	0,48	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12355	12355	A	G	MI.19264	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	19	7	M	V	Ata/Gta	-10,6	0	0	unknown	NA	neutral	0,38	neutral	3,86	neutral	1,04	neutral	-0,88	low_impact	1,83	neutral	0,81	neutral	0,88	neutral	-1,47	0	0,48	0,55	NA	NA	neutral	0,16	disease	0,58	neutral	0,21	6	neutral	0,62	deleterious	0,69	neutral	-4	neutral	0,17	high_impact	2,1	medium_impact	0,12	medium_impact	0,47	0,28	0,8	25,04	21,26	N	0,33	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12355	12355	A	C	MI.19265	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	19	7	M	L	Ata/Cta	-10,6	0	0	unknown	NA	neutral	1	neutral	3,9	neutral	1,6	neutral	-0,07	neutral_impact	0,36	neutral	0,9	neutral	0,99	neutral	-0,41	0,37	0,43	0,55	NA	NA	neutral	0,07	neutral	0,33	neutral	0,12	8	neutral	0	deleterious	1	neutral	-4	neutral	0,12	high_impact	2,1	high_impact	1,89	medium_impact	-0,87	0,45	0,8	25,04	21,26	N	0,44	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12355	12355	A	T	MI.19266	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	19	7	M	L	Ata/Tta	-10,6	0	0	unknown	NA	neutral	1	neutral	3,9	neutral	1,6	neutral	-0,07	neutral_impact	0,36	neutral	0,9	neutral	0,99	neutral	-0,22	0,99	0,43	0,55	NA	NA	neutral	0,07	neutral	0,33	neutral	0,12	8	neutral	0	deleterious	1	neutral	-4	neutral	0,12	high_impact	2,1	high_impact	1,89	medium_impact	-0,87	0,45	0,8	25,04	21,26	N	0,44	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12356	12356	T	A	MI.19267	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	20	7	M	K	aTa/aAa	-6,47	0	0	unknown	NA	neutral	0,16	neutral	3,81	neutral	0,37	neutral	-1,93	low_impact	1,83	neutral	0,78	neutral	0,81	neutral	1,12	11,34	0,25	0,45	NA	NA	neutral	0,33	disease	0,7	neutral	0,32	4	neutral	0,84	deleterious	0,58	neutral	-4	neutral	0,26	high_impact	2,1	medium_impact	-0,17	medium_impact	0,47	0,42	0,8	25,04	21,26	N	0,39	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12356	12356	T	C	MI.19268	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	20	7	M	T	aTa/aCa	-6,47	0	0	unknown	NA	neutral	0,56	neutral	3,83	neutral	0,5	neutral	-0,76	neutral_impact	0,8	neutral	0,89	neutral	0,93	neutral	-0,28	0,72	0,46	0,55	NA	NA	neutral	0,15	neutral	0,4	neutral	0,16	7	neutral	0,44	deleterious	0,78	neutral	-4	neutral	0,17	high_impact	2,1	medium_impact	0,29	medium_impact	-0,47	0,15	0,8	25,04	21,26	N	0,35	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12357	12357	A	T	MI.19269	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	21	7	M	I	atA/atT	-2,8	0	0	unknown	NA	neutral	0,61	neutral	3,84	neutral	0,75	neutral	-0,48	neutral_impact	0,28	neutral	0,91	neutral	0,97	neutral	-0,29	0,72	0,44	0,55	NA	NA	neutral	0,11	neutral	0,36	neutral	0,13	8	neutral	0,39	deleterious	0,81	neutral	-4	neutral	0,16	high_impact	2,1	medium_impact	0,34	medium_impact	-0,95	0,37	0,8	25,04	21,26	N	0,36	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5926	5926	T	C	MI.1927	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	23	8	F	S	tTc/tCc	7,53	1	0	probably_damaging	0,96	deleterious	0,04	neutral	-1,06	neutral	-1,94	neutral	-0,9	medium_impact	2	neutral	0,64	neutral	0,47	deleterious	4,08	23,7	0,23	0,55	neutral	0,32	disease	0,77	disease	0,59	disease	0,66	3	deleterious	0,99	neutral	0,04	deleterious	5	deleterious	0,75	low_impact	-2,06	medium_impact	-0,58	medium_impact	0,75	0,36	0,9	5,85	21,28	P	0,52	P	0,85	disease_causing	1	0,03	.	.	.	.	.	.	COSM1331634	.	.	.	.	.	.	.	.
chrM	12357	12357	A	C	MI.19270	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	21	7	M	I	atA/atC	-2,8	0	0	unknown	NA	neutral	0,61	neutral	3,84	neutral	0,75	neutral	-0,48	neutral_impact	0,28	neutral	0,91	neutral	0,97	neutral	-0,33	0,57	0,44	0,55	NA	NA	neutral	0,11	neutral	0,36	neutral	0,13	8	neutral	0,39	deleterious	0,81	neutral	-4	neutral	0,16	high_impact	2,1	medium_impact	0,34	medium_impact	-0,95	0,37	0,8	25,04	21,26	N	0,37	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12358	12358	A	C	MI.19271	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	22	8	T	P	Acc/Ccc	-9,22	0	0,16	unknown	NA	neutral	0,17	neutral	3,71	neutral	-1,88	neutral	-1,97	low_impact	1,94	neutral	0,72	neutral	0,86	deleterious	0,47	7,16	0,27	0,45	NA	NA	neutral	0,34	disease	0,55	neutral	0,27	5	neutral	0,83	deleterious	0,59	neutral	-4	neutral	0,25	high_impact	2,1	medium_impact	-0,15	medium_impact	0,57	0,52	0,8	19,9	15,82	N	0,42	N	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12358	12358	A	T	MI.19272	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	22	8	T	S	Acc/Tcc	-9,22	0	0,16	unknown	NA	neutral	0,69	neutral	3,78	neutral	-0,15	neutral	-0,89	low_impact	1,38	neutral	0,9	neutral	0,97	deleterious	0,01	2,71	0,57	0,65	NA	NA	neutral	0,08	neutral	0,17	neutral	0,11	8	neutral	0,31	deleterious	0,85	neutral	-4	neutral	0,13	high_impact	2,1	medium_impact	0,42	medium_impact	0,06	0,51	0,8	19,9	15,82	N	0,48	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12358	12358	A	G	MI.19273	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	22	8	T	A	Acc/Gcc	-9,22	0	0,16	unknown	NA	neutral	0,47	neutral	3,79	neutral	-0,19	neutral	-1,34	low_impact	1,04	neutral	0,88	neutral	0,92	deleterious	0,34	6,06	0,52	0,6	NA	NA	neutral	0,08	neutral	0,43	neutral	0,13	7	neutral	0,53	deleterious	0,74	neutral	-4	neutral	0,13	high_impact	2,1	medium_impact	0,2	medium_impact	-0,25	0,39	0,8	19,9	15,82	N	0,33	N	0,17	polymorphism	1	0,02	rs201027657	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12359	12359	C	G	MI.19274	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	23	8	T	S	aCc/aGc	-1,19	0	0	unknown	NA	neutral	0,69	neutral	3,78	neutral	-0,15	neutral	-0,89	low_impact	1,38	neutral	0,9	neutral	0,97	deleterious	0,19	4,61	0,57	0,65	NA	NA	neutral	0,08	neutral	0,17	neutral	0,11	8	neutral	0,31	deleterious	0,85	neutral	-4	neutral	0,13	high_impact	2,1	medium_impact	0,42	medium_impact	0,06	0,51	0,8	19,9	15,82	N	0,43	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12359	12359	C	A	MI.19275	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	23	8	T	N	aCc/aAc	-1,19	0	0	unknown	NA	neutral	0,58	neutral	3,73	neutral	-1,14	neutral	-1,52	low_impact	1,94	neutral	0,72	neutral	0,72	deleterious	0,78	9,34	0,6	0,65	NA	NA	neutral	0,18	neutral	0,41	neutral	0,21	6	neutral	0,42	deleterious	0,79	neutral	-4	neutral	0,16	high_impact	2,1	medium_impact	0,31	medium_impact	0,57	0,46	0,8	19,9	15,82	N	0,34	N	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12359	12359	C	T	MI.19276	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	23	8	T	I	aCc/aTc	-1,19	0	0	unknown	NA	neutral	1	neutral	3,78	neutral	-0,37	neutral	-0,32	neutral_impact	0,55	neutral	0,89	neutral	0,97	neutral	-0,38	0,42	0,36	0,5	NA	NA	neutral	0,1	neutral	0,24	neutral	0,12	8	neutral	0	deleterious	1	neutral	-4	neutral	0,16	high_impact	2,1	high_impact	1,89	medium_impact	-0,7	0,5	0,8	19,9	15,82	N	0,34	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12361	12361	A	C	MI.19277	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	25	9	T	P	Acc/Ccc	-3,71	0	0,06	unknown	NA	neutral	0,21	neutral	3,7	neutral	-2,49	neutral	-2	low_impact	1,2	neutral	0,82	neutral	0,69	deleterious	2,07	16,66	0,22	0,45	NA	NA	neutral	0,38	disease	0,52	neutral	0,29	4	neutral	0,79	deleterious	0,61	neutral	-4	neutral	0,27	high_impact	2,1	medium_impact	-0,09	medium_impact	-0,11	0,51	0,8	20,9	14,56	N	0,37	N	0,39	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12361	12361	A	T	MI.19278	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	25	9	T	S	Acc/Tcc	-3,71	0	0,06	unknown	NA	neutral	0,42	neutral	3,77	neutral	-0,75	neutral	-0,86	low_impact	0,85	neutral	0,91	neutral	0,94	deleterious	1,89	15,5	0,54	0,6	NA	NA	neutral	0,09	neutral	0,19	neutral	0,12	8	neutral	0,58	deleterious	0,71	neutral	-4	neutral	0,14	high_impact	2,1	medium_impact	0,16	medium_impact	-0,43	0,53	0,8	20,9	14,56	N	0,52	P	0,16	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12361	12361	A	G	MI.19279	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	25	9	T	A	Acc/Gcc	-3,71	0	0,06	unknown	NA	neutral	0,51	neutral	3,79	neutral	-0,37	neutral	-0,39	neutral_impact	0,65	neutral	0,88	neutral	0,91	deleterious	2,06	16,59	0,45	0,55	NA	NA	neutral	0,08	neutral	0,4	neutral	0,12	8	neutral	0,49	deleterious	0,76	neutral	-4	neutral	0,13	high_impact	2,1	medium_impact	0,24	medium_impact	-0,61	0,47	0,8	20,9	14,56	N	0,41	N	0,05	polymorphism	1	0,01	rs3134561	.	.	.	.	.	.	.	.	A12361G	Non alcoholic fatty liver disease	+	-	Reported	1
chrM	5927	5927	C	G	MI.1928	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	24	8	F	L	ttC/ttG	2,44	0,99	0	benign	0,21	deleterious	0,03	neutral	-1,01	neutral	-0,57	neutral	-0,61	medium_impact	2,06	neutral	0,64	neutral	0,51	deleterious	4,15	23,8	0,29	0,55	neutral	0,24	disease	0,64	neutral	0,38	neutral	0,48	0	neutral	0,97	neutral	0,41	deleterious	1	neutral	0,29	medium_impact	-0,22	medium_impact	-0,65	medium_impact	0,8	0,48	0,9	5,85	21,28	P	0,5	N	0,81	disease_causing	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12362	12362	C	G	MI.19280	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	26	9	T	S	aCc/aGc	-9,45	0	0	unknown	NA	neutral	0,42	neutral	3,77	neutral	-0,75	neutral	-0,86	low_impact	0,85	neutral	0,91	neutral	0,94	neutral	1,62	13,96	0,54	0,6	NA	NA	neutral	0,09	neutral	0,19	neutral	0,12	8	neutral	0,58	deleterious	0,71	neutral	-4	neutral	0,14	high_impact	2,1	medium_impact	0,16	medium_impact	-0,43	0,53	0,8	20,9	14,56	N	0,51	P	0,16	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12362	12362	C	T	MI.19281	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	26	9	T	I	aCc/aTc	-9,45	0	0	unknown	NA	neutral	0,4	neutral	3,79	neutral	-0,58	neutral	1,95	neutral_impact	-0,85	neutral	0,93	neutral	0,98	deleterious	0,37	6,39	0,32	0,5	NA	NA	neutral	0,11	neutral	0,18	neutral	0,13	7	neutral	0,6	deleterious	0,7	neutral	-4	neutral	0,16	high_impact	2,1	medium_impact	0,14	low_impact	-1,98	0,51	0,8	20,9	14,56	N	0,43	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12362	12362	C	A	MI.19282	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	26	9	T	N	aCc/aAc	-9,45	0	0	unknown	NA	neutral	0,31	neutral	3,72	neutral	-1,42	neutral	-2,01	low_impact	1,2	neutral	0,76	neutral	0,7	neutral	1,78	14,89	0,5	0,6	NA	NA	neutral	0,19	neutral	0,37	neutral	0,21	6	neutral	0,69	deleterious	0,66	neutral	-4	neutral	0,16	high_impact	2,1	medium_impact	0,04	medium_impact	-0,11	0,52	0,8	20,9	14,56	N	0,38	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12364	12364	C	A	MI.19283	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	28	10	L	M	Cta/Ata	-4,63	0	0	unknown	NA	neutral	0,22	neutral	3,54	neutral	-2,24	neutral	0,38	low_impact	1	neutral	0,85	neutral	0,96	deleterious	0,19	4,52	0,27	0,45	NA	NA	neutral	0,08	neutral	0,21	neutral	0,18	6	neutral	0,78	deleterious	0,61	neutral	-4	neutral	0,2	high_impact	2,1	medium_impact	-0,07	medium_impact	-0,29	0,59	0,8	7,96	10,12	N	0,49	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12364	12364	C	G	MI.19284	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	28	10	L	V	Cta/Gta	-4,63	0	0	unknown	NA	neutral	0,5	neutral	3,69	neutral	-0,55	neutral	-0,69	low_impact	1,27	neutral	0,85	neutral	0,97	deleterious	0,41	6,73	0,3	0,45	NA	NA	neutral	0,17	neutral	0,26	neutral	0,2	6	neutral	0,5	deleterious	0,75	neutral	-4	neutral	0,21	high_impact	2,1	medium_impact	0,23	medium_impact	-0,04	0,38	0,8	7,96	10,12	N	0,38	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12365	12365	T	G	MI.19285	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	29	10	L	R	cTa/cGa	-11,74	0	0	unknown	NA	neutral	0,35	neutral	3,5	deleterious	-3,07	deleterious	-3,46	medium_impact	2,42	damaging	0,57	neutral	0,57	deleterious	2,29	18,13	0,22	0,45	NA	NA	disease	0,66	disease	0,67	disease	0,7	4	neutral	0,65	deleterious	0,68	neutral	-1	deleterious	0,45	high_impact	2,1	medium_impact	0,08	medium_impact	1,01	0,43	0,8	7,96	10,12	N	0,34	N	0,76	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12365	12365	T	A	MI.19286	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	29	10	L	Q	cTa/cAa	-11,74	0	0	unknown	NA	neutral	0,29	neutral	3,49	deleterious	-3,12	deleterious	-3,01	medium_impact	2,42	neutral	0,63	neutral	0,65	deleterious	2,21	17,59	0,22	0,45	NA	NA	neutral	0,48	disease	0,54	neutral	0,44	1	neutral	0,71	deleterious	0,65	neutral	-1	neutral	0,28	high_impact	2,1	medium_impact	0,02	medium_impact	1,01	0,47	0,8	7,96	10,12	N	0,38	N	0,66	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12365	12365	T	C	MI.19287	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	29	10	L	P	cTa/cCa	-11,74	0	0	unknown	NA	neutral	0,2	neutral	3,48	deleterious	-3,92	deleterious	-3,91	medium_impact	2,42	damaging	0,53	neutral	0,58	deleterious	2,03	16,38	0,23	0,45	NA	NA	disease	0,55	disease	0,74	disease	0,73	5	neutral	0,8	deleterious	0,6	neutral	-1	deleterious	0,45	high_impact	2,1	medium_impact	-0,1	medium_impact	1,01	0,39	0,8	7,96	10,12	N	0,41	N	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12367	12367	A	G	MI.19288	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	31	11	T	A	Acc/Gcc	-11,51	0	0	unknown	NA	neutral	0,32	neutral	3,78	deleterious	-3,48	neutral	-2,31	low_impact	1,23	neutral	0,91	neutral	0,99	deleterious	0,19	4,57	0,56	0,6	NA	NA	neutral	0,11	neutral	0,23	neutral	0,18	6	neutral	0,68	deleterious	0,66	neutral	-4	neutral	0,15	high_impact	2,1	medium_impact	0,05	medium_impact	-0,08	0,4	0,8	18,57	13,16	N	0,45	N	0,03	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12367	12367	A	C	MI.19289	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	31	11	T	P	Acc/Ccc	-11,51	0	0	unknown	NA	neutral	0,11	neutral	3,67	deleterious	-6,34	deleterious	-3,89	medium_impact	2,58	neutral	0,63	neutral	0,52	neutral	1,54	13,53	0,27	0,45	NA	NA	disease	0,55	disease	0,53	disease	0,6	2	neutral	0,89	deleterious	0,56	neutral	-1	neutral	0,35	high_impact	2,1	medium_impact	-0,27	medium_impact	1,15	0,5	0,8	18,57	13,16	N	0,39	N	0,67	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5927	5927	C	A	MI.1929	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	24	8	F	L	ttC/ttA	2,44	0,99	0	benign	0,21	deleterious	0,03	neutral	-1,01	neutral	-0,57	neutral	-0,61	medium_impact	2,06	neutral	0,64	neutral	0,51	deleterious	4,39	24,1	0,29	0,55	neutral	0,24	disease	0,64	neutral	0,38	neutral	0,48	0	neutral	0,97	neutral	0,41	deleterious	1	neutral	0,29	medium_impact	-0,22	medium_impact	-0,65	medium_impact	0,8	0,48	0,9	5,85	21,28	P	0,51	P	0,81	disease_causing	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12367	12367	A	T	MI.19290	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	31	11	T	S	Acc/Tcc	-11,51	0	0	unknown	NA	neutral	0,79	neutral	3,74	deleterious	-4,44	neutral	-1,66	low_impact	1,14	neutral	0,89	neutral	0,98	neutral	-0,31	0,62	0,63	0,65	NA	NA	neutral	0,09	neutral	0,18	neutral	0,19	6	neutral	0,21	deleterious	0,9	neutral	-4	neutral	0,16	high_impact	2,1	medium_impact	0,55	medium_impact	-0,16	0,51	0,8	18,57	13,16	N	0,41	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12368	12368	C	T	MI.19291	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	32	11	T	I	aCc/aTc	-0,5	0	0	unknown	NA	neutral	0,58	neutral	3,8	deleterious	-5,23	deleterious	-2,52	low_impact	1,34	neutral	0,89	neutral	0,96	neutral	-0,08	1,92	0,41	0,5	NA	NA	neutral	0,22	neutral	0,22	neutral	0,19	6	neutral	0,42	deleterious	0,79	neutral	-4	neutral	0,19	high_impact	2,1	medium_impact	0,31	medium_impact	0,02	0,52	0,8	18,57	13,16	N	0,33	N	0,22	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12368	12368	C	A	MI.19292	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	32	11	T	N	aCc/aAc	-0,5	0	0	unknown	NA	neutral	0,15	neutral	3,69	deleterious	-5,88	deleterious	-3,13	medium_impact	2,58	neutral	0,74	neutral	0,64	deleterious	1,86	15,35	0,56	0,6	NA	NA	neutral	0,34	neutral	0,24	neutral	0,21	6	neutral	0,85	deleterious	0,58	neutral	-1	neutral	0,21	high_impact	2,1	medium_impact	-0,18	medium_impact	1,15	0,53	0,8	18,57	13,16	N	0,43	N	0,45	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12368	12368	C	G	MI.19293	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	32	11	T	S	aCc/aGc	-0,5	0	0	unknown	NA	neutral	0,79	neutral	3,74	deleterious	-4,44	neutral	-1,66	low_impact	1,14	neutral	0,89	neutral	0,98	neutral	-0,11	1,66	0,63	0,65	NA	NA	neutral	0,09	neutral	0,18	neutral	0,19	6	neutral	0,21	deleterious	0,9	neutral	-4	neutral	0,16	high_impact	2,1	medium_impact	0,55	medium_impact	-0,16	0,51	0,8	18,57	13,16	N	0,37	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12370	12370	C	A	MI.19294	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	34	12	L	M	Ctg/Atg	-5,55	0	0	unknown	NA	neutral	0,23	neutral	3,41	deleterious	-5,57	neutral	-1,25	low_impact	1,38	neutral	0,82	neutral	0,9	deleterious	0,79	9,4	0,31	0,45	NA	NA	neutral	0,12	neutral	0,2	neutral	0,21	6	neutral	0,77	deleterious	0,62	neutral	-4	neutral	0,25	high_impact	2,1	medium_impact	-0,06	medium_impact	0,06	0,66	0,8	20,56	12,96	N	0,46	N	0,58	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12370	12370	C	G	MI.19295	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	34	12	L	V	Ctg/Gtg	-5,55	0	0	unknown	NA	neutral	0,17	neutral	3,49	deleterious	-5,41	neutral	-2,27	medium_impact	2,4	neutral	0,81	neutral	0,7	neutral	1,54	13,55	0,33	0,5	NA	NA	neutral	0,18	neutral	0,2	neutral	0,21	6	neutral	0,83	deleterious	0,59	neutral	-1	neutral	0,24	high_impact	2,1	medium_impact	-0,15	medium_impact	0,99	0,37	0,8	20,56	12,96	N	0,4	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12371	12371	T	C	MI.19296	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	35	12	L	P	cTg/cCg	-3,71	0	0	unknown	NA	neutral	0,11	neutral	3,35	deleterious	-9,49	deleterious	-5,83	medium_impact	2,74	neutral	0,64	damaging	0,13	deleterious	2,01	16,3	0,23	0,45	NA	NA	disease	0,54	disease	0,71	disease	0,72	4	neutral	0,89	deleterious	0,56	neutral	-1	deleterious	0,5	high_impact	2,1	medium_impact	-0,27	medium_impact	1,3	0,37	0,8	20,56	12,96	N	0,25	N	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12371	12371	T	G	MI.19297	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	35	12	L	R	cTg/cGg	-3,71	0	0	unknown	NA	neutral	0,09	neutral	3,36	deleterious	-9,06	deleterious	-4,99	medium_impact	2,74	neutral	0,68	damaging	0,13	deleterious	2,32	18,29	0,23	0,45	NA	NA	disease	0,63	disease	0,7	disease	0,72	4	neutral	0,91	deleterious	0,55	neutral	-1	deleterious	0,48	high_impact	2,1	medium_impact	-0,32	medium_impact	1,3	0,45	0,8	20,56	12,96	N	0,27	N	0,99	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12371	12371	T	A	MI.19298	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	35	12	L	Q	cTg/cAg	-3,71	0	0	unknown	NA	neutral	0,06	neutral	3,36	deleterious	-8,93	deleterious	-4,92	medium_impact	2,74	neutral	0,74	damaging	0,19	deleterious	2,33	18,34	0,23	0,45	NA	NA	neutral	0,47	disease	0,59	neutral	0,46	1	neutral	0,94	deleterious	0,53	neutral	-1	neutral	0,33	high_impact	2,1	medium_impact	-0,43	medium_impact	1,3	0,49	0,8	20,56	12,96	N	0,36	N	0,96	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12373	12373	A	T	MI.19299	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	37	13	T	S	Act/Tct	-4,86	0	0	unknown	NA	neutral	0,38	neutral	3,75	neutral	-1,17	neutral	-1,14	low_impact	1,38	neutral	0,88	neutral	0,98	neutral	-0,37	0,47	0,44	0,55	NA	NA	neutral	0,11	neutral	0,19	neutral	0,22	6	neutral	0,62	deleterious	0,69	neutral	-4	neutral	0,15	high_impact	2,1	medium_impact	0,12	medium_impact	0,06	0,4	0,8	20,07	13,72	N	0,53	P	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8617	8617	A	T	MI.193	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	91	31	I	F	Atc/Ttc	-2,65	0	0	benign	0,17	neutral	1	neutral	4,36	neutral	-1,22	neutral	1,85	neutral_impact	-0,65	neutral	0,85	neutral	0,95	neutral	-0,91	0,03	0,44	0,65	neutral	0,25	neutral	0,21	neutral	0,18	neutral	0,37	3	neutral	0,17	deleterious	0,92	neutral	-6	neutral	0,3	medium_impact	-0,1	high_impact	1,98	low_impact	-1,66	0,48	0,9	28,32	22,32	N	0,3	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5928	5928	T	A	MI.1930	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	25	9	S	T	Tct/Act	-3,11	0	0	probably_damaging	0,9	neutral	0,11	neutral	-0,78	neutral	-1,64	neutral	-0,47	low_impact	1,5	damaging	0,54	damaging	0,15	deleterious	3,54	23,1	0,22	0,55	neutral	0,16	disease	0,66	disease	0,62	disease	0,59	2	neutral	0,96	neutral	0,11	neutral	-2	deleterious	0,66	low_impact	-1,65	medium_impact	-0,31	medium_impact	0,29	0,7	0,9	1,17	6,83	N	0,33	N	0,42	polymorphism	0,58	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12373	12373	A	C	MI.19300	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	37	13	T	P	Act/Cct	-4,86	0	0	unknown	NA	deleterious	0,04	neutral	3,69	deleterious	-3,32	deleterious	-2,73	medium_impact	2,29	neutral	0,65	neutral	0,54	deleterious	0,27	5,38	0,25	0,45	NA	NA	neutral	0,48	disease	0,61	disease	0,51	0	neutral	0,96	deleterious	0,52	deleterious	3	neutral	0,32	high_impact	2,1	medium_impact	-0,53	medium_impact	0,89	0,45	0,8	20,07	13,72	N	0,37	N	0,75	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12373	12373	A	G	MI.19301	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	37	13	T	A	Act/Gct	-4,86	0	0	unknown	NA	neutral	0,25	neutral	3,8	neutral	-0,98	neutral	-1,13	low_impact	1,25	neutral	0,88	neutral	0,94	neutral	-0,33	0,57	0,49	0,55	NA	NA	neutral	0,06	neutral	0,38	neutral	0,17	7	neutral	0,75	deleterious	0,63	neutral	-4	neutral	0,13	high_impact	2,1	medium_impact	-0,03	medium_impact	-0,06	0,43	0,8	20,07	13,72	N	0,52	P	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12374	12374	C	G	MI.19302	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	38	13	T	S	aCt/aGt	-8,53	0	0	unknown	NA	neutral	0,38	neutral	3,75	neutral	-1,17	neutral	-1,14	low_impact	1,38	neutral	0,88	neutral	0,98	neutral	-0,13	1,51	0,44	0,55	NA	NA	neutral	0,11	neutral	0,19	neutral	0,22	6	neutral	0,62	deleterious	0,69	neutral	-4	neutral	0,15	high_impact	2,1	medium_impact	0,12	medium_impact	0,06	0,4	0,8	20,07	13,72	N	0,52	P	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12374	12374	C	A	MI.19303	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	38	13	T	N	aCt/aAt	-8,53	0	0	unknown	NA	neutral	0,15	neutral	3,7	neutral	-2,98	neutral	-2,33	medium_impact	2,29	neutral	0,77	neutral	0,67	deleterious	0,21	4,78	0,47	0,55	NA	NA	neutral	0,28	neutral	0,48	neutral	0,21	6	neutral	0,85	deleterious	0,58	neutral	-1	neutral	0,19	high_impact	2,1	medium_impact	-0,18	medium_impact	0,89	0,7	0,85	20,07	13,72	N	0,39	N	0,59	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12374	12374	C	T	MI.19304	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	38	13	T	I	aCt/aTt	-8,53	0	0	unknown	NA	neutral	0,35	neutral	3,81	neutral	-0,07	neutral	0,53	low_impact	0,86	neutral	0,88	neutral	0,95	deleterious	-0,02	2,43	0,3	0,45	NA	NA	neutral	0,12	neutral	0,15	neutral	0,19	6	neutral	0,65	deleterious	0,68	neutral	-4	neutral	0,15	high_impact	2,1	medium_impact	0,08	medium_impact	-0,42	0,55	0,8	20,07	13,72	N	0,55	P	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12376	12376	T	G	MI.19305	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	40	14	S	A	Tcc/Gcc	-7,84	0	0	unknown	NA	neutral	0,11	neutral	3,84	neutral	0,24	neutral	0,1	low_impact	1,23	neutral	0,86	neutral	0,85	deleterious	0,73	9,04	0,34	0,5	NA	NA	neutral	0,06	neutral	0,13	neutral	0,18	6	neutral	0,89	deleterious	0,56	neutral	-4	neutral	0,13	high_impact	2,1	medium_impact	-0,27	medium_impact	-0,08	0,48	0,8	27,36	21,95	P	0,6	P	0,15	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12376	12376	T	C	MI.19306	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	40	14	S	P	Tcc/Ccc	-7,84	0	0	unknown	NA	neutral	0,11	neutral	3,77	neutral	-2,03	neutral	-1,39	low_impact	1,57	neutral	0,77	neutral	0,81	neutral	0,91	10,16	0,35	0,5	NA	NA	neutral	0,35	neutral	0,29	neutral	0,15	7	neutral	0,89	deleterious	0,56	neutral	-4	neutral	0,28	high_impact	2,1	medium_impact	-0,27	medium_impact	0,23	0,53	0,8	27,36	21,95	N	0,43	N	0,63	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12376	12376	T	A	MI.19307	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	40	14	S	T	Tcc/Acc	-7,84	0	0	unknown	NA	neutral	0,55	neutral	3,82	neutral	0,33	neutral	0,79	neutral_impact	0,68	neutral	0,9	neutral	0,97	deleterious	0,56	7,87	0,39	0,5	NA	NA	neutral	0,04	neutral	0,08	neutral	0,17	7	neutral	0,45	deleterious	0,78	neutral	-4	neutral	0,1	high_impact	2,1	medium_impact	0,28	medium_impact	-0,58	0,7	0,85	27,36	21,95	N	0,48	N	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12377	12377	C	A	MI.19308	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	41	14	S	Y	tCc/tAc	-1,42	0	0	unknown	NA	neutral	0,18	neutral	3,74	neutral	-1,07	neutral	-0,37	medium_impact	2,12	neutral	0,82	neutral	0,69	neutral	1,05	10,96	0,32	0,5	NA	NA	neutral	0,2	neutral	0,35	neutral	0,21	6	neutral	0,82	deleterious	0,59	neutral	-1	neutral	0,19	high_impact	2,1	medium_impact	-0,13	medium_impact	0,73	0,55	0,8	27,36	21,95	N	0,43	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12377	12377	C	T	MI.19309	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	41	14	S	F	tCc/tTc	-1,42	0	0	unknown	NA	neutral	0,62	neutral	3,76	neutral	-0,24	neutral	0,42	low_impact	1,57	neutral	0,78	neutral	0,67	neutral	1,25	11,98	0,28	0,45	NA	NA	neutral	0,22	neutral	0,37	neutral	0,18	6	neutral	0,38	deleterious	0,81	neutral	-4	neutral	0,19	high_impact	2,1	medium_impact	0,35	medium_impact	0,23	0,43	0,8	27,36	21,95	N	0,27	N	0,47	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5928	5928	T	C	MI.1931	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	25	9	S	P	Tct/Cct	-3,11	0	0	probably_damaging	0,99	deleterious	0	neutral	-0,81	deleterious	-3,19	neutral	-0,78	medium_impact	3,34	damaging	0,43	damaging	0,21	deleterious	3,77	23,4	0,2	0,55	disease	0,72	disease	0,81	disease	0,75	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,85	low_impact	-2,64	low_impact	-1,48	medium_impact	1,99	0,55	0,9	1,17	6,83	N	0,51	P	0,91	disease_causing	0,82	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12377	12377	C	G	MI.19310	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	41	14	S	C	tCc/tGc	-1,42	0	0	unknown	NA	neutral	0,08	neutral	3,72	neutral	-1,76	neutral	-0,31	medium_impact	2,12	neutral	0,71	neutral	0,64	neutral	1,71	14,49	0,33	0,5	NA	NA	neutral	0,23	neutral	0,41	neutral	0,16	7	neutral	0,92	deleterious	0,54	neutral	-1	neutral	0,17	high_impact	2,1	medium_impact	-0,35	medium_impact	0,73	0,56	0,8	27,36	21,95	N	0,5	N	0,45	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12379	12379	C	A	MI.19311	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	43	15	L	M	Cta/Ata	-8,53	0	0	unknown	NA	neutral	0,19	neutral	3,26	deleterious	-7,85	neutral	-1,89	medium_impact	2,49	neutral	0,64	damaging	0,26	deleterious	1,85	15,3	0,29	0,45	NA	NA	neutral	0,23	neutral	0,25	neutral	0,2	6	neutral	0,81	deleterious	0,6	neutral	-1	neutral	0,3	high_impact	2,1	medium_impact	-0,12	medium_impact	1,07	0,75	0,85	8,29	7,07	N	0,37	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12379	12379	C	G	MI.19312	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	43	15	L	V	Cta/Gta	-8,53	0	0	unknown	NA	neutral	0,26	neutral	3,35	deleterious	-7,52	deleterious	-2,75	medium_impact	3,04	neutral	0,65	damaging	0,27	neutral	1,57	13,7	0,29	0,45	NA	NA	neutral	0,21	neutral	0,25	neutral	0,21	6	neutral	0,74	deleterious	0,63	neutral	-1	neutral	0,31	high_impact	2,1	medium_impact	-0,02	medium_impact	1,57	0,5	0,8	8,29	7,07	N	0,37	N	0,78	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12380	12380	T	G	MI.19313	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	44	15	L	R	cTa/cGa	-0,5	0	0	unknown	NA	neutral	0,05	neutral	3,21	deleterious	-10,26	deleterious	-5,57	medium_impact	3,04	damaging	0,55	damaging	0,13	deleterious	2,3	18,17	0,21	0,45	NA	NA	disease	0,64	disease	0,74	disease	0,72	4	neutral	0,95	deleterious	0,53	neutral	-1	deleterious	0,52	high_impact	2,1	medium_impact	-0,47	medium_impact	1,57	0,4	0,8	8,29	7,07	N	0,28	N	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12380	12380	T	A	MI.19314	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	44	15	L	Q	cTa/cAa	-0,5	0	0	unknown	NA	deleterious	0,04	neutral	3,21	deleterious	-10,41	deleterious	-5,57	medium_impact	3,04	damaging	0,56	damaging	0,14	deleterious	2,22	17,64	0,22	0,45	NA	NA	disease	0,52	disease	0,62	disease	0,64	3	neutral	0,96	deleterious	0,52	deleterious	3	neutral	0,39	high_impact	2,1	medium_impact	-0,53	medium_impact	1,57	0,5	0,8	8,29	7,07	N	0,29	N	0,98	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12380	12380	T	C	MI.19315	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	44	15	L	P	cTa/cCa	-0,5	0	0	unknown	NA	neutral	0,06	neutral	3,2	deleterious	-10,6	deleterious	-5,74	medium_impact	3,04	damaging	0,49	damaging	0,13	deleterious	2,05	16,53	0,26	0,45	NA	NA	disease	0,52	disease	0,74	disease	0,72	4	neutral	0,94	deleterious	0,53	neutral	-1	deleterious	0,55	high_impact	2,1	medium_impact	-0,43	medium_impact	1,57	0,44	0,8	8,29	7,07	N	0,3	N	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12382	12382	A	C	MI.19316	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	46	16	I	L	Att/Ctt	-5,78	0	0	unknown	NA	neutral	1	neutral	3,85	neutral	-0,9	neutral	-0,04	neutral_impact	0,53	neutral	0,86	neutral	0,97	neutral	-0,48	0,24	0,36	0,5	NA	NA	neutral	0,11	neutral	0,08	neutral	0,2	6	neutral	0	deleterious	1	neutral	-4	neutral	0,17	high_impact	2,1	high_impact	1,89	medium_impact	-0,72	0,31	0,8	11,94	9,03	N	0,34	N	0,13	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12382	12382	A	G	MI.19317	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	46	16	I	V	Att/Gtt	-5,78	0	0	unknown	NA	neutral	0,35	neutral	3,77	neutral	-0,53	neutral	-0,11	low_impact	1,26	neutral	0,89	neutral	0,95	neutral	-0,74	0,06	0,47	0,55	NA	NA	neutral	0,06	neutral	0,15	neutral	0,2	6	neutral	0,65	deleterious	0,68	neutral	-4	neutral	0,15	high_impact	2,1	medium_impact	0,08	medium_impact	-0,05	0,17	0,8	11,94	9,03	P	0,57	P	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12382	12382	A	T	MI.19318	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	46	16	I	F	Att/Ttt	-5,78	0	0	unknown	NA	neutral	0,98	neutral	3,68	neutral	-2,88	neutral	-1,99	low_impact	1,36	neutral	0,88	neutral	0,88	neutral	-0,22	0,99	0,38	0,5	NA	NA	neutral	0,27	neutral	0,15	neutral	0,18	6	neutral	0,02	deleterious	0,99	neutral	-4	neutral	0,22	high_impact	2,1	medium_impact	1,17	medium_impact	0,04	0,29	0,8	11,94	9,03	N	0,3	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12383	12383	T	G	MI.19319	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	47	16	I	S	aTt/aGt	-2,8	0	0	unknown	NA	neutral	0,36	neutral	3,66	neutral	-2,64	neutral	-2,01	low_impact	1,36	neutral	0,89	neutral	0,89	deleterious	0,85	9,77	0,27	0,45	NA	NA	neutral	0,42	neutral	0,22	neutral	0,21	6	neutral	0,64	deleterious	0,68	neutral	-4	neutral	0,25	high_impact	2,1	medium_impact	0,1	medium_impact	0,04	0,31	0,8	11,94	9,03	N	0,37	N	0,35	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5928	5928	T	G	MI.1932	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	25	9	S	A	Tct/Gct	-3,11	0	0	probably_damaging	0,95	neutral	0,05	neutral	-0,75	neutral	-0,86	neutral	-0,47	medium_impact	2,67	neutral	0,64	damaging	0,2	deleterious	3,46	23	0,28	0,55	neutral	0,18	disease	0,59	disease	0,68	disease	0,58	2	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,62	low_impact	-1,96	medium_impact	-0,52	medium_impact	1,37	0,64	0,9	1,17	6,83	N	0,38	N	0,33	polymorphism	0,82	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12383	12383	T	A	MI.19320	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	47	16	I	N	aTt/aAt	-2,8	0	0	unknown	NA	neutral	0,15	neutral	3,62	deleterious	-3,82	deleterious	-3,03	low_impact	1,82	neutral	0,75	neutral	0,56	neutral	1,22	11,83	0,26	0,45	NA	NA	neutral	0,44	neutral	0,48	neutral	0,24	5	neutral	0,85	deleterious	0,58	neutral	-4	neutral	0,31	high_impact	2,1	medium_impact	-0,18	medium_impact	0,46	0,42	0,8	11,94	9,03	N	0,4	N	0,53	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12383	12383	T	C	MI.19321	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	47	16	I	T	aTt/aCt	-2,8	0	0	unknown	NA	neutral	0,44	neutral	3,7	neutral	2,01	neutral	-0,12	neutral_impact	0,01	neutral	0,92	neutral	0,97	neutral	-0,85	0,03	0,27	0,45	NA	NA	neutral	0,11	neutral	0,16	neutral	0,23	5	neutral	0,56	deleterious	0,72	neutral	-4	neutral	0,2	high_impact	2,1	medium_impact	0,18	low_impact	-1,19	0,22	0,8	11,94	9,03	N	0,47	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12384	12384	T	A	MI.19322	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	48	16	I	M	atT/atA	-4,17	0	0,01	unknown	NA	neutral	0,36	neutral	3,66	neutral	-2,28	neutral	-0,3	low_impact	1,36	neutral	0,87	neutral	0,94	deleterious	0,32	5,89	0,44	0,55	NA	NA	neutral	0,13	neutral	0,13	neutral	0,23	5	neutral	0,64	deleterious	0,68	neutral	-4	neutral	0,24	high_impact	2,1	medium_impact	0,1	medium_impact	0,04	0,3	0,8	11,94	9,03	P	0,54	P	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12384	12384	T	G	MI.19323	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	48	16	I	M	atT/atG	-4,17	0	0,01	unknown	NA	neutral	0,36	neutral	3,66	neutral	-2,28	neutral	-0,3	low_impact	1,36	neutral	0,87	neutral	0,94	deleterious	0,05	3,03	0,44	0,55	NA	NA	neutral	0,13	neutral	0,13	neutral	0,23	5	neutral	0,64	deleterious	0,68	neutral	-4	neutral	0,24	high_impact	2,1	medium_impact	0,1	medium_impact	0,04	0,3	0,8	11,94	9,03	P	0,53	P	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12385	12385	C	T	MI.19324	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	49	17	P	S	Ccc/Tcc	-15,41	0	0	unknown	NA	neutral	0,39	neutral	3,82	neutral	1,46	neutral	0,99	low_impact	0,9	neutral	0,95	neutral	0,95	deleterious	0,47	7,17	0,33	0,5	NA	NA	neutral	0,07	neutral	0,24	neutral	0,2	6	neutral	0,61	deleterious	0,7	neutral	-4	neutral	0,09	high_impact	2,1	medium_impact	0,13	medium_impact	-0,38	0,24	0,8	21,39	11,59	N	0,45	N	0,15	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12385	12385	C	A	MI.19325	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	49	17	P	T	Ccc/Acc	-15,41	0	0	unknown	NA	neutral	0,5	neutral	3,83	neutral	2,53	neutral	1,92	neutral_impact	0,5	neutral	0,9	neutral	0,93	deleterious	0,25	5,25	0,3	0,45	NA	NA	neutral	0,04	neutral	0,22	neutral	0,18	6	neutral	0,5	deleterious	0,75	neutral	-4	neutral	0,1	high_impact	2,1	medium_impact	0,23	medium_impact	-0,75	0,48	0,8	21,39	11,59	N	0,39	N	0,06	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12385	12385	C	G	MI.19326	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	49	17	P	A	Ccc/Gcc	-15,41	0	0	unknown	NA	neutral	0,29	neutral	3,87	neutral	2,72	neutral	1,47	low_impact	1,01	neutral	0,9	neutral	0,93	neutral	-0,41	0,36	0,26	0,45	NA	NA	neutral	0,03	neutral	0,26	neutral	0,18	6	neutral	0,71	deleterious	0,65	neutral	-4	neutral	0,13	high_impact	2,1	medium_impact	0,02	medium_impact	-0,28	0,51	0,8	21,39	11,59	N	0,46	N	0,34	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12386	12386	C	A	MI.19327	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	50	17	P	H	cCc/cAc	-4,63	0	0	unknown	NA	neutral	0,17	neutral	3,77	neutral	-0,03	neutral	0,03	low_impact	1,7	neutral	0,78	neutral	0,75	deleterious	0,51	7,48	0,28	0,45	NA	NA	neutral	0,13	disease	0,56	neutral	0,23	5	neutral	0,83	deleterious	0,59	neutral	-4	neutral	0,16	high_impact	2,1	medium_impact	-0,15	medium_impact	0,35	0,36	0,8	21,39	11,59	N	0,43	N	0,63	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12386	12386	C	G	MI.19328	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	50	17	P	R	cCc/cGc	-4,63	0	0	unknown	NA	neutral	0,11	neutral	3,78	neutral	0,54	neutral	0,17	low_impact	1,36	neutral	0,79	neutral	0,71	deleterious	0,39	6,56	0,25	0,45	NA	NA	neutral	0,2	disease	0,61	neutral	0,3	4	neutral	0,89	deleterious	0,56	neutral	-4	neutral	0,21	high_impact	2,1	medium_impact	-0,27	medium_impact	0,04	0,42	0,8	21,39	11,59	N	0,41	N	0,64	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12386	12386	C	T	MI.19329	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	50	17	P	L	cCc/cTc	-4,63	0	0	unknown	NA	neutral	1	neutral	3,91	neutral	5,4	neutral	3,64	neutral_impact	-0,6	neutral	0,88	neutral	0,97	deleterious	0,29	5,63	0,28	0,45	NA	NA	neutral	0,07	neutral	0,22	neutral	0,21	6	neutral	0	deleterious	1	neutral	-4	neutral	0,13	high_impact	2,1	high_impact	1,89	low_impact	-1,75	0,82	0,85	21,39	11,59	N	0,28	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5929	5929	C	T	MI.1933	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	26	9	S	F	tCt/tTt	4,75	1	0	probably_damaging	1	deleterious	0	neutral	-0,82	deleterious	-3,53	neutral	-0,93	high_impact	3,69	damaging	0,39	damaging	0,12	deleterious	3,98	23,6	0,14	0,55	disease	0,8	disease	0,86	disease	0,76	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,31	0,37	0,9	1,17	6,83	P	0,69	P	0,98	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12388	12388	C	G	MI.19330	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	52	18	P	A	Ccc/Gcc	-9,91	0	0	unknown	NA	neutral	0,09	neutral	3,72	deleterious	-10,67	deleterious	-6,54	medium_impact	3,16	neutral	0,66	neutral	0,56	neutral	1,27	12,1	0,37	0,5	NA	NA	neutral	0,36	neutral	0,42	neutral	0,17	7	neutral	0,91	deleterious	0,55	neutral	-1	neutral	0,34	high_impact	2,1	medium_impact	-0,32	medium_impact	1,68	0,7	0,85	27,36	7,17	N	0,43	N	0,71	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12388	12388	C	T	MI.19331	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	52	18	P	S	Ccc/Tcc	-9,91	0	0	unknown	NA	neutral	0,15	neutral	3,68	deleterious	-10,99	deleterious	-6,66	medium_impact	2,61	neutral	0,66	neutral	0,57	deleterious	2,09	16,78	0,4	0,5	NA	NA	disease	0,6	neutral	0,24	neutral	0,48	1	neutral	0,85	deleterious	0,58	neutral	-1	neutral	0,43	high_impact	2,1	medium_impact	-0,18	medium_impact	1,18	0,29	0,8	27,36	7,17	N	0,38	N	0,75	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12388	12388	C	A	MI.19332	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	52	18	P	T	Ccc/Acc	-9,91	0	0	unknown	NA	neutral	0,18	neutral	3,68	deleterious	-11,42	deleterious	-6,31	medium_impact	2,82	neutral	0,71	neutral	0,51	deleterious	1,86	15,33	0,37	0,5	NA	NA	disease	0,57	neutral	0,24	disease	0,51	0	neutral	0,82	deleterious	0,59	neutral	-1	neutral	0,37	high_impact	2,1	medium_impact	-0,13	medium_impact	1,37	0,56	0,8	27,36	7,17	N	0,38	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12389	12389	C	A	MI.19333	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	53	18	P	H	cCc/cAc	1,56	0,23	0	unknown	NA	neutral	0,07	neutral	3,62	deleterious	-12,94	deleterious	-7,59	medium_impact	3,16	neutral	0,65	neutral	0,45	deleterious	2,2	17,52	0,34	0,5	NA	NA	disease	0,71	neutral	0,39	disease	0,53	1	neutral	0,93	deleterious	0,54	neutral	-1	deleterious	0,49	high_impact	2,1	medium_impact	-0,39	medium_impact	1,68	0,45	0,8	27,36	7,17	N	0,4	N	0,73	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12389	12389	C	G	MI.19334	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	53	18	P	R	cCc/cGc	1,56	0,23	0	unknown	NA	neutral	0,05	neutral	3,65	deleterious	-11,98	deleterious	-7,58	medium_impact	3,16	neutral	0,63	neutral	0,51	neutral	1,78	14,84	0,28	0,45	NA	NA	disease	0,73	disease	0,64	disease	0,67	3	neutral	0,95	deleterious	0,53	neutral	-1	deleterious	0,48	high_impact	2,1	medium_impact	-0,47	medium_impact	1,68	0,55	0,8	27,36	7,17	N	0,38	N	0,69	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12389	12389	C	T	MI.19335	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	53	18	P	L	cCc/cTc	1,56	0,23	0	unknown	NA	neutral	1	neutral	3,73	deleterious	-11,93	deleterious	-6,12	medium_impact	2,27	neutral	0,7	neutral	0,61	neutral	1,49	13,28	0,27	0,45	NA	NA	disease	0,62	neutral	0,26	neutral	0,4	2	neutral	0	deleterious	1	neutral	-1	neutral	0,39	high_impact	2,1	high_impact	1,89	medium_impact	0,87	0,77	0,85	27,36	7,17	N	0,26	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12391	12391	A	T	MI.19336	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	55	19	I	F	Atc/Ttc	-13,12	0	0	unknown	NA	neutral	0,69	neutral	3,56	deleterious	-6,88	deleterious	-3,35	medium_impact	2,42	neutral	0,75	neutral	0,69	deleterious	2,02	16,35	0,41	0,5	NA	NA	disease	0,52	neutral	0,43	neutral	0,49	0	neutral	0,31	deleterious	0,85	neutral	-1	neutral	0,32	high_impact	2,1	medium_impact	0,42	medium_impact	1,01	0,41	0,8	17,91	12,47	N	0,32	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12391	12391	A	G	MI.19337	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	55	19	I	V	Atc/Gtc	-13,12	0	0	unknown	NA	neutral	0,25	neutral	3,72	deleterious	-3,24	neutral	-0,69	low_impact	1,77	neutral	0,92	neutral	0,95	neutral	-0,2	1,12	0,48	0,55	NA	NA	neutral	0,09	neutral	0,16	neutral	0,22	6	neutral	0,75	deleterious	0,63	neutral	-4	neutral	0,16	high_impact	2,1	medium_impact	-0,03	medium_impact	0,41	0,24	0,8	17,91	12,47	P	0,57	P	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12391	12391	A	C	MI.19338	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	55	19	I	L	Atc/Ctc	-13,12	0	0	unknown	NA	neutral	1	neutral	3,9	deleterious	-4,29	neutral	-1,35	low_impact	1,18	neutral	0,85	neutral	0,91	neutral	-0,09	1,77	0,34	0,5	NA	NA	neutral	0,14	neutral	0,16	neutral	0,26	5	neutral	0	deleterious	1	neutral	-4	neutral	0,19	high_impact	2,1	high_impact	1,89	medium_impact	-0,13	0,34	0,8	17,91	12,47	N	0,32	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12392	12392	T	A	MI.19339	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	56	19	I	N	aTc/aAc	0,18	0	0	unknown	NA	neutral	0,12	neutral	3,5	deleterious	-8,6	deleterious	-5,86	medium_impact	2,96	neutral	0,73	neutral	0,53	deleterious	2,61	20,3	0,29	0,45	NA	NA	disease	0,68	disease	0,57	disease	0,72	4	neutral	0,88	deleterious	0,56	neutral	-1	deleterious	0,46	high_impact	2,1	medium_impact	-0,25	medium_impact	1,5	0,4	0,8	17,91	12,47	N	0,38	N	0,97	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5929	5929	C	G	MI.1934	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	26	9	S	C	tCt/tGt	4,75	1	0	probably_damaging	1	deleterious	0	neutral	-0,82	neutral	0,51	neutral	-0,78	medium_impact	3,27	damaging	0,52	damaging	0,15	deleterious	3,39	23	0,2	0,55	disease	0,61	disease	0,79	disease	0,72	disease	0,74	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	medium_impact	1,92	0,67	0,9	1,17	6,83	P	0,49	N	0,84	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12392	12392	T	G	MI.19340	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	56	19	I	S	aTc/aGc	0,18	0	0	unknown	NA	neutral	0,44	neutral	3,52	deleterious	-7,5	deleterious	-4,94	medium_impact	2,96	neutral	0,77	neutral	0,56	deleterious	2,48	19,36	0,34	0,5	NA	NA	disease	0,68	neutral	0,48	disease	0,53	1	neutral	0,56	deleterious	0,72	neutral	-1	neutral	0,41	high_impact	2,1	medium_impact	0,18	medium_impact	1,5	0,34	0,8	17,91	12,47	N	0,36	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12392	12392	T	C	MI.19341	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	56	19	I	T	aTc/aCc	0,18	0	0	unknown	NA	neutral	0,33	neutral	3,55	deleterious	-5,33	deleterious	-3,64	medium_impact	2,27	neutral	0,87	neutral	0,72	neutral	1,53	13,46	0,34	0,5	NA	NA	neutral	0,41	neutral	0,26	neutral	0,21	6	neutral	0,67	deleterious	0,67	neutral	-1	neutral	0,35	high_impact	2,1	medium_impact	0,06	medium_impact	0,87	0,31	0,8	17,91	12,47	N	0,43	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12393	12393	C	G	MI.19342	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	57	19	I	M	atC/atG	3,63	0,35	0	unknown	NA	neutral	0,25	neutral	3,54	deleterious	-6,51	neutral	-2	medium_impact	2,16	neutral	0,85	neutral	0,87	deleterious	0,48	7,27	0,57	0,65	NA	NA	neutral	0,31	neutral	0,2	neutral	0,21	6	neutral	0,75	deleterious	0,63	neutral	-1	neutral	0,31	high_impact	2,1	medium_impact	-0,03	medium_impact	0,77	0,56	0,8	17,91	12,47	N	0,41	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12393	12393	C	A	MI.19343	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	57	19	I	M	atC/atA	3,63	0,35	0	unknown	NA	neutral	0,25	neutral	3,54	deleterious	-6,51	neutral	-2	medium_impact	2,16	neutral	0,85	neutral	0,87	neutral	0,95	10,4	0,57	0,65	NA	NA	neutral	0,31	neutral	0,2	neutral	0,21	6	neutral	0,75	deleterious	0,63	neutral	-1	neutral	0,31	high_impact	2,1	medium_impact	-0,03	medium_impact	0,77	0,56	0,8	17,91	12,47	N	0,41	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12394	12394	C	A	MI.19344	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	58	20	L	I	Ctt/Att	-7,61	0	0	unknown	NA	neutral	0,58	neutral	3,66	neutral	1,23	neutral	-0,24	neutral_impact	0,3	neutral	0,89	neutral	0,98	deleterious	0,11	3,71	0,47	0,55	NA	NA	neutral	0,06	neutral	0,12	neutral	0,23	5	neutral	0,42	deleterious	0,79	neutral	-4	neutral	0,25	high_impact	2,1	medium_impact	0,31	medium_impact	-0,93	0,63	0,8	13,1	10,78	N	0,48	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12394	12394	C	T	MI.19345	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	58	20	L	F	Ctt/Ttt	-7,61	0	0	unknown	NA	neutral	0,73	neutral	3,56	neutral	-1,84	neutral	-1,94	low_impact	0,85	neutral	0,89	neutral	0,86	deleterious	0,86	9,81	0,63	0,7	NA	NA	neutral	0,24	neutral	0,22	neutral	0,21	6	neutral	0,27	deleterious	0,87	neutral	-4	neutral	0,33	high_impact	2,1	medium_impact	0,47	medium_impact	-0,43	0,56	0,8	13,1	10,78	N	0,23	N	0,04	polymorphism	1	0,03	rs28709525	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12394	12394	C	G	MI.19346	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	58	20	L	V	Ctt/Gtt	-7,61	0	0	unknown	NA	neutral	0,41	neutral	3,64	neutral	-0,18	neutral	-0,65	low_impact	1,26	neutral	0,87	neutral	0,95	deleterious	0,12	3,83	0,54	0,6	NA	NA	neutral	0,2	neutral	0,17	neutral	0,22	6	neutral	0,59	deleterious	0,71	neutral	-4	neutral	0,32	high_impact	2,1	medium_impact	0,15	medium_impact	-0,05	0,54	0,8	13,1	10,78	N	0,47	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12395	12395	T	A	MI.19347	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	59	20	L	H	cTt/cAt	-5,09	0	0	unknown	NA	neutral	0,28	neutral	3,49	deleterious	-4,7	deleterious	-4,19	medium_impact	2,23	neutral	0,68	neutral	0,55	deleterious	2,28	18,03	0,27	0,45	NA	NA	disease	0,56	neutral	0,5	disease	0,54	1	neutral	0,72	deleterious	0,64	neutral	-1	deleterious	0,44	high_impact	2,1	medium_impact	0,01	medium_impact	0,83	0,48	0,8	13,1	10,78	N	0,37	N	0,61	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12395	12395	T	G	MI.19348	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	59	20	L	R	cTt/cGt	-5,09	0	0	unknown	NA	neutral	0,21	neutral	3,5	deleterious	-4,04	deleterious	-3,72	medium_impact	2,23	neutral	0,65	neutral	0,52	deleterious	2,33	18,38	0,3	0,45	NA	NA	disease	0,7	disease	0,68	disease	0,74	5	neutral	0,79	deleterious	0,61	neutral	-1	deleterious	0,55	high_impact	2,1	medium_impact	-0,09	medium_impact	0,83	0,49	0,8	13,1	10,78	N	0,32	N	0,54	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12395	12395	T	C	MI.19349	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	59	20	L	P	cTt/cCt	-5,09	0	0	unknown	NA	neutral	0,2	neutral	3,49	deleterious	-4,51	deleterious	-3,65	medium_impact	2,23	damaging	0,59	neutral	0,43	deleterious	1,96	15,93	0,44	0,55	NA	NA	disease	0,72	disease	0,63	disease	0,73	5	neutral	0,8	deleterious	0,6	neutral	-1	deleterious	0,62	high_impact	2,1	medium_impact	-0,1	medium_impact	0,83	0,41	0,8	13,1	10,78	N	0,31	N	0,77	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5929	5929	C	A	MI.1935	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	26	9	S	Y	tCt/tAt	4,75	1	0	probably_damaging	1	deleterious	0	neutral	-0,82	deleterious	-3,89	neutral	-0,93	high_impact	3,69	damaging	0,55	damaging	0,15	deleterious	3,82	23,4	0,15	0,55	disease	0,82	disease	0,86	disease	0,76	disease	0,83	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,31	0,61	0,9	1,17	6,83	P	0,49	N	0,92	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12397	12397	A	C	MI.19350	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	61	21	T	P	Acc/Ccc	-20	0	0,01	unknown	NA	neutral	0,36	neutral	3,69	deleterious	-3,09	neutral	-1,52	low_impact	1,15	neutral	0,74	neutral	0,71	deleterious	0,43	6,85	0,42	0,55	NA	NA	disease	0,59	neutral	0,25	neutral	0,47	1	neutral	0,64	deleterious	0,68	neutral	-4	neutral	0,43	high_impact	2,1	medium_impact	0,1	medium_impact	-0,15	0,7	0,85	27,69	13,06	N	0,38	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12397	12397	A	G	MI.19351	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	61	21	T	A	Acc/Gcc	-20	0	0,01	unknown	NA	neutral	0,46	neutral	3,81	neutral	-0,2	neutral	-0,74	neutral_impact	-0,74	neutral	0,88	neutral	0,94	deleterious	0,01	2,7	0,66	0,7	NA	NA	neutral	0,16	neutral	0,17	neutral	0,26	5	neutral	0,54	deleterious	0,73	neutral	-4	neutral	0,26	high_impact	2,1	medium_impact	0,19	low_impact	-1,88	0,32	0,8	27,69	13,06	N	0,5	N	0,02	polymorphism	1	0,01	rs200890363	other	Parkinson_disease_6,_autosomal_recessive_early-onset	RCV000010351.3	MedGen:OMIM	.	.	.	.	A12397G	PD,early onset	+	-	Reported	2
chrM	12397	12397	A	T	MI.19352	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	61	21	T	S	Acc/Tcc	-20	0	0,01	unknown	NA	neutral	0,43	neutral	3,77	neutral	-1,18	neutral	-1,08	low_impact	1,15	neutral	0,86	neutral	0,95	neutral	-0,09	1,8	0,68	0,7	NA	NA	neutral	0,18	neutral	0,29	neutral	0,24	5	neutral	0,57	deleterious	0,72	neutral	-4	neutral	0,25	high_impact	2,1	medium_impact	0,17	medium_impact	-0,15	0,61	0,8	27,69	13,06	N	0,41	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12398	12398	C	G	MI.19353	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	62	21	T	S	aCc/aGc	-7,16	0	0	unknown	NA	neutral	0,43	neutral	3,77	neutral	-1,18	neutral	-1,08	low_impact	1,15	neutral	0,86	neutral	0,95	deleterious	0,12	3,84	0,68	0,7	NA	NA	neutral	0,18	neutral	0,29	neutral	0,24	5	neutral	0,57	deleterious	0,72	neutral	-4	neutral	0,25	high_impact	2,1	medium_impact	0,17	medium_impact	-0,15	0,61	0,8	27,69	13,06	N	0,4	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12398	12398	C	A	MI.19354	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	62	21	T	N	aCc/aAc	-7,16	0	0	unknown	NA	neutral	0,33	neutral	3,7	neutral	-2,71	neutral	-2	neutral_impact	0,7	neutral	0,79	neutral	0,74	deleterious	0,47	7,16	0,73	0,75	NA	NA	neutral	0,39	neutral	0,42	neutral	0,2	6	neutral	0,67	deleterious	0,67	neutral	-4	neutral	0,3	high_impact	2,1	medium_impact	0,06	medium_impact	-0,56	0,72	0,85	27,69	13,06	N	0,33	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12398	12398	C	T	MI.19355	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	62	21	T	I	aCc/aTc	-7,16	0	0	unknown	NA	neutral	0,46	neutral	3,78	neutral	-0,25	neutral	0,38	neutral_impact	0,26	neutral	0,86	neutral	0,9	deleterious	0,47	7,18	0,62	0,65	NA	NA	neutral	0,29	neutral	0,16	neutral	0,21	6	neutral	0,54	deleterious	0,73	neutral	-4	neutral	0,29	high_impact	2,1	medium_impact	0,19	medium_impact	-0,97	0,53	0,8	27,69	13,06	N	0,43	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12400	12400	A	T	MI.19356	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	64	22	T	S	Acc/Tcc	-1,65	0	0	unknown	NA	neutral	0,52	neutral	3,78	neutral	-0,67	neutral	0,23	low_impact	0,96	neutral	0,84	neutral	0,96	deleterious	0,05	3,11	0,72	0,75	NA	NA	neutral	0,13	neutral	0,16	neutral	0,24	5	neutral	0,48	deleterious	0,76	neutral	-4	neutral	0,25	high_impact	2,1	medium_impact	0,25	medium_impact	-0,33	0,65	0,8	21,23	15,61	N	0,43	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12400	12400	A	C	MI.19357	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	64	22	T	P	Acc/Ccc	-1,65	0	0	unknown	NA	neutral	0,35	neutral	3,69	deleterious	-4,49	neutral	-2,06	low_impact	1,62	neutral	0,82	neutral	0,91	neutral	1,02	10,78	0,39	0,5	NA	NA	neutral	0,42	neutral	0,3	neutral	0,21	6	neutral	0,65	deleterious	0,68	neutral	-4	neutral	0,35	high_impact	2,1	medium_impact	0,08	medium_impact	0,28	0,63	0,8	21,23	15,61	N	0,4	N	0,55	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12400	12400	A	G	MI.19358	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	64	22	T	A	Acc/Gcc	-1,65	0	0	unknown	NA	neutral	0,51	neutral	3,78	neutral	-2,23	neutral	-1,5	low_impact	1	neutral	0,84	neutral	0,88	neutral	1,03	10,81	0,71	0,75	NA	NA	neutral	0,18	neutral	0,38	neutral	0,21	6	neutral	0,49	deleterious	0,76	neutral	-4	neutral	0,25	high_impact	2,1	medium_impact	0,24	medium_impact	-0,29	0,25	0,8	21,23	15,61	N	0,31	N	0	polymorphism	1	0,03	rs201405598	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12401	12401	C	G	MI.19359	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	65	22	T	S	aCc/aGc	-4,17	0	0	unknown	NA	neutral	0,52	neutral	3,78	neutral	-0,67	neutral	0,23	low_impact	0,96	neutral	0,84	neutral	0,96	neutral	-0,21	1,03	0,72	0,75	NA	NA	neutral	0,13	neutral	0,16	neutral	0,24	5	neutral	0,48	deleterious	0,76	neutral	-4	neutral	0,25	high_impact	2,1	medium_impact	0,25	medium_impact	-0,33	0,65	0,8	21,23	15,61	N	0,43	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5931	5931	A	C	MI.1936	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	28	10	T	P	Aca/Cca	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	-0,84	neutral	-2,85	neutral	-0,94	high_impact	4,33	damaging	0,57	damaging	0,17	deleterious	3,31	22,9	0,11	0,55	disease	0,71	disease	0,84	disease	0,75	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,9	0,5	0,9	2,34	6,72	N	0,43	N	0,91	disease_causing	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12401	12401	C	T	MI.19360	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	65	22	T	I	aCc/aTc	-4,17	0	0	unknown	NA	neutral	0,55	neutral	3,74	neutral	-2,75	deleterious	-3,1	medium_impact	2,24	neutral	0,81	neutral	0,88	deleterious	2,08	16,74	0,53	0,6	NA	NA	neutral	0,37	neutral	0,24	neutral	0,21	6	neutral	0,45	deleterious	0,78	neutral	-1	neutral	0,28	high_impact	2,1	medium_impact	0,28	medium_impact	0,84	0,55	0,8	21,23	15,61	N	0,29	N	0,4	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12401	12401	C	A	MI.19361	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	65	22	T	N	aCc/aAc	-4,17	0	0	unknown	NA	neutral	0,35	neutral	3,71	deleterious	-3,1	neutral	-1,43	low_impact	1,9	neutral	0,81	neutral	0,86	deleterious	0,45	7,07	0,64	0,7	NA	NA	neutral	0,36	neutral	0,2	neutral	0,2	6	neutral	0,65	deleterious	0,68	neutral	-4	neutral	0,29	high_impact	2,1	medium_impact	0,08	medium_impact	0,53	0,64	0,8	21,23	15,61	N	0,4	N	0,15	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12403	12403	C	A	MI.19362	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	67	23	L	I	Ctc/Atc	-11,97	0	0,01	unknown	NA	neutral	0,6	neutral	3,62	neutral	-1,31	neutral	-0,41	medium_impact	2,44	neutral	0,86	neutral	0,97	deleterious	0,88	9,92	0,44	0,55	NA	NA	neutral	0,23	neutral	0,16	neutral	0,21	6	neutral	0,4	deleterious	0,8	neutral	-1	neutral	0,32	high_impact	2,1	medium_impact	0,33	medium_impact	1,03	0,68	0,85	22,06	19,72	N	0,44	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12403	12403	C	T	MI.19363	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	67	23	L	F	Ctc/Ttc	-11,97	0	0,01	unknown	NA	neutral	0,9	neutral	3,56	neutral	-1,67	neutral	-0,92	low_impact	1,63	neutral	0,86	neutral	0,94	deleterious	0,63	8,39	0,61	0,65	NA	NA	neutral	0,34	neutral	0,17	neutral	0,2	6	neutral	0,1	deleterious	0,95	neutral	-4	neutral	0,35	high_impact	2,1	medium_impact	0,76	medium_impact	0,29	0,52	0,8	22,06	19,72	N	0,37	N	0,29	polymorphism	1	0,02	rs879096684	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12403	12403	C	G	MI.19364	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	67	23	L	V	Ctc/Gtc	-11,97	0	0,01	unknown	NA	neutral	0,5	neutral	3,61	neutral	-0,63	neutral	-0,74	medium_impact	2,78	neutral	0,69	neutral	0,69	deleterious	0,52	7,55	0,52	0,6	NA	NA	neutral	0,36	neutral	0,34	neutral	0,19	6	neutral	0,5	deleterious	0,75	neutral	-1	neutral	0,34	high_impact	2,1	medium_impact	0,23	medium_impact	1,34	0,62	0,8	22,06	19,72	N	0,42	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12404	12404	T	C	MI.19365	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	68	23	L	P	cTc/cCc	-4,86	0	0	unknown	NA	neutral	0,25	neutral	3,48	neutral	-1,64	neutral	-1,84	medium_impact	2,23	neutral	0,8	neutral	0,74	neutral	1,01	10,7	0,3	0,45	NA	NA	disease	0,74	neutral	0,43	disease	0,56	1	neutral	0,75	deleterious	0,63	neutral	-1	deleterious	0,6	high_impact	2,1	medium_impact	-0,03	medium_impact	0,83	0,41	0,8	22,06	19,72	N	0,3	N	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12404	12404	T	A	MI.19366	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	68	23	L	H	cTc/cAc	-4,86	0	0	unknown	NA	neutral	0,42	neutral	3,48	neutral	-1,99	neutral	-1,99	medium_impact	2,78	neutral	0,74	neutral	0,59	neutral	1,2	11,74	0,36	0,5	NA	NA	disease	0,65	neutral	0,47	disease	0,54	1	neutral	0,58	deleterious	0,71	neutral	-1	deleterious	0,49	high_impact	2,1	medium_impact	0,16	medium_impact	1,34	0,54	0,8	22,06	19,72	N	0,31	N	0,75	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12404	12404	T	G	MI.19367	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	68	23	L	R	cTc/cGc	-4,86	0	0	unknown	NA	neutral	0,3	neutral	3,49	neutral	-0,94	neutral	-2,03	medium_impact	2,78	damaging	0,6	neutral	0,54	deleterious	2,3	18,18	0,25	0,45	NA	NA	disease	0,75	disease	0,58	disease	0,69	4	neutral	0,7	deleterious	0,65	neutral	-1	deleterious	0,58	high_impact	2,1	medium_impact	0,03	medium_impact	1,34	0,43	0,8	22,06	19,72	N	0,33	N	0,58	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12406	12406	G	A	MI.19368	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	70	24	V	I	Gtt/Att	-11,51	0	0,14	benign	0	neutral	0,43	neutral	3,82	neutral	-0,09	neutral	-0,39	neutral_impact	-0,34	neutral	0,86	neutral	0,96	neutral	-0,37	0,45	0,75	0,8	NA	NA	neutral	0,04	neutral	0,13	neutral	0,2	6	neutral	0,57	deleterious	0,72	neutral	-6	neutral	0,06	high_impact	2,1	medium_impact	0,17	low_impact	-1,51	0,84	0,9	24,71	20,09	N	0,51	P	0	polymorphism	1	0	rs28617389	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12406	12406	G	T	MI.19369	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	70	24	V	F	Gtt/Ttt	-11,51	0	0,14	benign	0,32	neutral	0,57	neutral	3,7	neutral	-0,53	neutral	-1,48	neutral_impact	0,78	neutral	0,83	neutral	0,95	deleterious	0,07	3,32	0,51	0,6	NA	NA	neutral	0,27	neutral	0,16	neutral	0,16	7	neutral	0,34	deleterious	0,63	neutral	-6	neutral	0,28	medium_impact	-0,44	medium_impact	0,3	medium_impact	-0,49	0,51	0,8	24,71	20,09	N	0,42	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5931	5931	A	G	MI.1937	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	28	10	T	A	Aca/Gca	-3,34	0	0	probably_damaging	0,97	deleterious	0	neutral	-0,79	neutral	-0,64	neutral	-0,8	medium_impact	3,43	neutral	0,9	damaging	0,17	deleterious	3,28	22,8	0,44	0,55	neutral	0,4	disease	0,7	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,69	low_impact	-2,18	low_impact	-1,48	high_impact	2,07	0,43	0,9	2,34	6,72	N	0,42	N	0,65	disease_causing	0,95	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12406	12406	G	C	MI.19370	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	70	24	V	L	Gtt/Ctt	-11,51	0	0,14	benign	0,06	neutral	1	neutral	3,82	neutral	0,49	neutral	-0,43	low_impact	0,9	neutral	0,82	neutral	0,96	neutral	-0,54	0,18	0,66	0,7	NA	NA	neutral	0,1	neutral	0,1	neutral	0,22	6	neutral	0,06	deleterious	0,97	neutral	-6	neutral	0,08	medium_impact	0,39	high_impact	1,89	medium_impact	-0,38	0,58	0,8	24,71	20,09	N	0,38	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12407	12407	T	A	MI.19371	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	71	24	V	D	gTt/gAt	-2,34	0	0	possibly_damaging	0,74	neutral	0,12	neutral	3,64	neutral	-1,93	neutral	-1,58	low_impact	1,59	neutral	0,78	neutral	0,67	neutral	1,41	12,82	0,45	0,55	NA	NA	neutral	0,4	disease	0,61	neutral	0,31	4	neutral	0,91	neutral	0,19	neutral	-3	deleterious	0,54	low_impact	-1,18	medium_impact	-0,25	medium_impact	0,25	0,64	0,8	24,71	20,09	N	0,35	N	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12407	12407	T	C	MI.19372	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	71	24	V	A	gTt/gCt	-2,34	0	0	benign	0,15	neutral	0,27	neutral	3,74	neutral	-0,11	neutral	-0,15	low_impact	1,25	neutral	0,85	neutral	0,96	neutral	-0,15	1,41	0,67	0,7	NA	NA	neutral	0,09	neutral	0,37	neutral	0,24	5	neutral	0,69	deleterious	0,56	neutral	-6	neutral	0,18	medium_impact	-0,03	medium_impact	-0,01	medium_impact	-0,06	0,42	0,8	24,71	20,09	N	0,48	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12407	12407	T	G	MI.19373	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	71	24	V	G	gTt/gGt	-2,34	0	0	possibly_damaging	0,56	neutral	0,31	neutral	3,65	neutral	-1,78	neutral	-2,14	low_impact	1,25	neutral	0,74	neutral	0,65	deleterious	0,58	8,02	0,51	0,6	NA	NA	neutral	0,22	disease	0,51	neutral	0,21	6	neutral	0,69	neutral	0,38	neutral	-3	neutral	0,38	medium_impact	-0,85	medium_impact	0,04	medium_impact	-0,06	0,68	0,85	24,71	20,09	N	0,38	N	0,31	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12409	12409	A	G	MI.19374	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	73	25	N	D	Aac/Gac	-11,74	0	0	benign	0,08	neutral	0,21	neutral	3,75	neutral	-2,03	neutral	-2,16	medium_impact	2,16	neutral	0,84	neutral	0,94	deleterious	0,45	7,02	0,84	0,85	NA	NA	neutral	0,26	neutral	0,35	neutral	0,18	6	neutral	0,77	deleterious	0,57	neutral	-3	neutral	0,23	medium_impact	0,26	medium_impact	-0,09	medium_impact	0,77	0,44	0,8	25,21	13,1	N	0,47	N	0,7	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12409	12409	A	T	MI.19375	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	73	25	N	Y	Aac/Tac	-11,74	0	0	possibly_damaging	0,59	neutral	1	neutral	3,71	deleterious	-3,8	deleterious	-3,06	medium_impact	1,96	neutral	0,84	neutral	0,72	deleterious	0,8	9,44	0,57	0,65	NA	NA	neutral	0,41	neutral	0,33	neutral	0,18	6	neutral	0,59	deleterious	0,71	NA	0	deleterious	0,56	medium_impact	-0,9	high_impact	1,89	medium_impact	0,59	0,57	0,8	25,21	13,1	N	0,25	N	0,92	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12409	12409	A	C	MI.19376	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	73	25	N	H	Aac/Cac	-11,74	0	0	possibly_damaging	0,59	neutral	0,54	neutral	3,72	deleterious	-3,34	neutral	-2,2	medium_impact	2,5	neutral	0,79	neutral	0,79	deleterious	0,16	4,24	0,74	0,8	NA	NA	neutral	0,3	neutral	0,23	neutral	0,2	6	neutral	0,55	deleterious	0,48	NA	0	deleterious	0,51	medium_impact	-0,9	medium_impact	0,27	medium_impact	1,08	0,49	0,8	25,21	13,1	N	0,32	N	0,52	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12410	12410	A	G	MI.19377	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	74	25	N	S	aAc/aGc	-4,4	0	0	benign	0,01	neutral	0,45	neutral	3,82	neutral	-0,88	neutral	-1,7	low_impact	0,96	neutral	0,9	neutral	0,99	neutral	-0,63	0,11	0,81	0,85	NA	NA	neutral	0,12	neutral	0,16	neutral	0,23	5	neutral	0,54	deleterious	0,72	neutral	-6	neutral	0,1	medium_impact	1,15	medium_impact	0,18	medium_impact	-0,33	0,2	0,8	25,21	13,1	N	0,5	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12410	12410	A	T	MI.19378	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	74	25	N	I	aAc/aTc	-4,4	0	0	benign	0,28	neutral	0,42	neutral	3,73	deleterious	-3,86	deleterious	-4,29	medium_impact	2,16	neutral	0,81	neutral	0,65	neutral	0,89	10,01	0,55	0,6	NA	NA	neutral	0,39	neutral	0,18	neutral	0,21	6	neutral	0,49	deleterious	0,57	neutral	-3	deleterious	0,45	medium_impact	-0,36	medium_impact	0,16	medium_impact	0,77	0,51	0,8	25,21	13,1	N	0,43	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12410	12410	A	C	MI.19379	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	74	25	N	T	aAc/aCc	-4,4	0	0	benign	0,01	neutral	0,46	neutral	3,78	neutral	-1,52	neutral	-2,15	low_impact	1,47	neutral	0,89	neutral	0,96	neutral	-0,18	1,18	0,64	0,7	NA	NA	neutral	0,25	neutral	0,15	neutral	0,2	6	neutral	0,53	deleterious	0,73	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,19	medium_impact	0,14	0,43	0,8	25,21	13,1	N	0,44	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5931	5931	A	T	MI.1938	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	28	10	T	S	Aca/Tca	-3,34	0	0	probably_damaging	0,97	neutral	0,11	neutral	-0,81	neutral	1,19	neutral	-0,64	medium_impact	2,69	neutral	0,67	damaging	0,17	deleterious	3,2	22,7	0,36	0,55	neutral	0,44	disease	0,68	disease	0,62	neutral	0,48	0	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,75	low_impact	-2,18	medium_impact	-0,31	medium_impact	1,39	0,59	0,9	2,34	6,72	N	0,36	N	0,77	disease_causing	0,87	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12411	12411	C	A	MI.19380	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	75	25	N	K	aaC/aaA	-0,5	0	0	benign	0	neutral	0,33	neutral	3,83	neutral	-0,66	neutral	-2,04	low_impact	1,53	neutral	0,89	neutral	0,91	deleterious	0,62	8,32	0,84	0,85	NA	NA	neutral	0,25	neutral	0,38	neutral	0,17	7	neutral	0,67	deleterious	0,67	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,06	medium_impact	0,2	0,56	0,8	25,21	13,1	N	0,42	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12411	12411	C	G	MI.19381	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	75	25	N	K	aaC/aaG	-0,5	0	0	benign	0	neutral	0,33	neutral	3,83	neutral	-0,66	neutral	-2,04	low_impact	1,53	neutral	0,89	neutral	0,91	deleterious	0,19	4,54	0,84	0,85	NA	NA	neutral	0,25	neutral	0,38	neutral	0,17	7	neutral	0,67	deleterious	0,67	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,06	medium_impact	0,2	0,56	0,8	25,21	13,1	N	0,4	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12412	12412	C	G	MI.19382	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	76	26	P	A	Cct/Gct	-3,94	0	0	benign	0,31	neutral	0,51	neutral	3,78	neutral	1,06	neutral	0,75	medium_impact	2,5	neutral	0,81	neutral	0,86	neutral	-0,09	1,8	0,58	0,65	NA	NA	neutral	0,33	neutral	0,4	neutral	0,18	6	neutral	0,4	deleterious	0,6	neutral	-3	neutral	0,32	medium_impact	-0,42	medium_impact	0,24	medium_impact	1,08	0,76	0,85	23,71	19,47	N	0,32	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12412	12412	C	T	MI.19383	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	76	26	P	S	Cct/Tct	-3,94	0	0	benign	0,04	neutral	0,46	neutral	3,77	neutral	0,59	neutral	0,72	low_impact	1,61	neutral	0,85	neutral	0,91	deleterious	0,69	8,79	0,64	0,7	NA	NA	neutral	0,5	neutral	0,21	neutral	0,41	2	neutral	0,51	deleterious	0,71	neutral	-6	neutral	0,43	medium_impact	0,57	medium_impact	0,19	medium_impact	0,27	0,19	0,8	23,71	19,47	N	0,36	N	0,57	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12412	12412	C	A	MI.19384	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	76	26	P	T	Cct/Act	-3,94	0	0	benign	0,06	neutral	0,46	neutral	3,76	neutral	2,05	neutral	1,61	low_impact	1,12	neutral	0,87	neutral	0,96	deleterious	0,31	5,81	0,55	0,6	NA	NA	disease	0,5	neutral	0,2	neutral	0,41	2	neutral	0,49	deleterious	0,7	neutral	-6	neutral	0,12	medium_impact	0,39	medium_impact	0,19	medium_impact	-0,18	0,68	0,85	23,71	19,47	N	0,34	N	0,2	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12413	12413	C	A	MI.19385	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	77	26	P	H	cCt/cAt	-4,63	0	0	probably_damaging	0,94	neutral	0,54	neutral	3,7	neutral	-1,28	neutral	-0,29	medium_impact	2,16	neutral	0,77	neutral	0,63	deleterious	2,48	19,33	0,65	0,7	NA	NA	disease	0,61	neutral	0,33	disease	0,52	0	neutral	0,94	neutral	0,3	deleterious	1	deleterious	0,71	low_impact	-1,88	medium_impact	0,27	medium_impact	0,77	0,56	0,8	23,71	19,47	N	0,24	N	0,86	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12413	12413	C	G	MI.19386	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	77	26	P	R	cCt/cGt	-4,63	0	0	possibly_damaging	0,84	neutral	0,35	neutral	3,75	neutral	-0,57	neutral	-0,02	medium_impact	2,5	neutral	0,72	neutral	0,61	deleterious	2,01	16,27	0,49	0,55	NA	NA	disease	0,66	disease	0,57	disease	0,62	2	neutral	0,86	neutral	0,26	NA	0	deleterious	0,63	low_impact	-1,43	medium_impact	0,08	medium_impact	1,08	0,59	0,8	23,71	19,47	N	0,38	N	0,8	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12413	12413	C	T	MI.19387	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	77	26	P	L	cCt/cTt	-4,63	0	0	possibly_damaging	0,56	neutral	0,73	neutral	3,76	neutral	2,41	neutral	2,08	low_impact	1,09	neutral	0,8	neutral	0,9	deleterious	0,87	9,89	0,5	0,6	NA	NA	disease	0,56	neutral	0,24	neutral	0,44	1	neutral	0,47	deleterious	0,59	neutral	-3	neutral	0,42	medium_impact	-0,85	medium_impact	0,47	medium_impact	-0,21	0,72	0,85	23,71	19,47	N	0,26	N	0,24	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12415	12415	A	G	MI.19388	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	79	27	N	D	Aac/Gac	-10,6	0	0	benign	0,01	neutral	0,22	neutral	3,78	neutral	-0,56	neutral	-1,31	medium_impact	2,33	neutral	0,79	neutral	0,72	deleterious	2,34	18,41	0,83	0,85	NA	NA	neutral	0,29	neutral	0,37	neutral	0,17	7	neutral	0,78	deleterious	0,61	neutral	-3	deleterious	0,68	medium_impact	1,15	medium_impact	-0,07	medium_impact	0,93	0,73	0,85	28,52	20	N	0,44	N	0,44	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12415	12415	A	C	MI.19389	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	79	27	N	H	Aac/Cac	-10,6	0	0	benign	0,02	neutral	0,54	neutral	3,74	neutral	3	neutral	3,07	low_impact	1,64	neutral	0,82	neutral	0,99	deleterious	0,84	9,69	0,79	0,8	NA	NA	neutral	0,21	neutral	0,24	neutral	0,17	7	neutral	0,43	deleterious	0,76	neutral	-6	deleterious	0,68	medium_impact	0,86	medium_impact	0,27	medium_impact	0,3	0,72	0,85	28,52	20	N	0,35	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5932	5932	C	A	MI.1939	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	29	10	T	K	aCa/aAa	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	-0,84	neutral	-1,94	neutral	-0,96	high_impact	3,77	neutral	0,73	damaging	0,14	deleterious	4,24	23,9	0,18	0,55	disease	0,59	disease	0,89	disease	0,77	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	2,38	0,54	0,9	2,34	6,72	P	0,54	P	0,87	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12415	12415	A	T	MI.19390	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	79	27	N	Y	Aac/Tac	-10,6	0	0	benign	0,02	neutral	1	neutral	3,73	neutral	8	neutral	3,91	neutral_impact	0,55	neutral	0,88	neutral	0,96	deleterious	0,82	9,62	0,66	0,7	NA	NA	neutral	0,28	neutral	0,24	neutral	0,17	7	neutral	0,02	deleterious	0,99	neutral	-6	deleterious	0,69	medium_impact	0,86	high_impact	1,89	medium_impact	-0,7	0,75	0,85	28,52	20	N	0,29	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12416	12416	A	G	MI.19391	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	80	27	N	S	aAc/aGc	-2,8	0	0	benign	0,03	neutral	0,43	neutral	3,82	neutral	0,21	neutral	-0,7	medium_impact	1,98	neutral	0,86	neutral	0,85	neutral	1,25	11,99	0,86	0,9	NA	NA	neutral	0,22	neutral	0,19	neutral	0,18	6	neutral	0,54	deleterious	0,7	neutral	-3	deleterious	0,68	medium_impact	0,69	medium_impact	0,17	medium_impact	0,61	0,62	0,8	28,52	20	N	0,46	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12416	12416	A	C	MI.19392	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	80	27	N	T	aAc/aCc	-2,8	0	0	benign	0,25	neutral	0,4	neutral	3,8	neutral	-0,17	neutral	-0,75	low_impact	1,52	neutral	0,84	neutral	0,88	neutral	1,54	13,5	0,72	0,75	NA	NA	neutral	0,25	neutral	0,17	neutral	0,17	7	neutral	0,52	deleterious	0,58	neutral	-6	deleterious	0,67	medium_impact	-0,29	medium_impact	0,14	medium_impact	0,19	0,76	0,85	28,52	20	N	0,48	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12416	12416	A	T	MI.19393	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	80	27	N	I	aAc/aTc	-2,8	0	0	possibly_damaging	0,65	neutral	0,41	neutral	3,75	neutral	0,2	neutral	-0,89	medium_impact	2,33	neutral	0,85	neutral	0,91	deleterious	2,1	16,88	0,59	0,65	NA	NA	neutral	0,39	neutral	0,38	neutral	0,16	7	neutral	0,67	neutral	0,38	NA	0	deleterious	0,7	low_impact	-1	medium_impact	0,15	medium_impact	0,93	0,62	0,8	28,52	20	N	0,36	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12417	12417	C	G	MI.19394	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	81	27	N	K	aaC/aaG	-0,96	0	0	benign	0,25	neutral	0,3	neutral	3,83	neutral	0,43	neutral	-0,7	low_impact	1,64	neutral	0,78	neutral	0,76	deleterious	2,24	17,76	0,81	0,85	NA	NA	neutral	0,25	neutral	0,2	neutral	0,17	7	neutral	0,64	deleterious	0,53	neutral	-6	deleterious	0,7	medium_impact	-0,29	medium_impact	0,03	medium_impact	0,3	0,76	0,85	28,52	20	N	0,46	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12417	12417	C	A	MI.19395	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	81	27	N	K	aaC/aaA	-0,96	0	0	benign	0,25	neutral	0,3	neutral	3,83	neutral	0,43	neutral	-0,7	low_impact	1,64	neutral	0,78	neutral	0,76	deleterious	2,72	20,9	0,81	0,85	NA	NA	neutral	0,25	neutral	0,2	neutral	0,17	7	neutral	0,64	deleterious	0,53	neutral	-6	deleterious	0,7	medium_impact	-0,29	medium_impact	0,03	medium_impact	0,3	0,76	0,85	28,52	20	N	0,46	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12418	12418	A	G	MI.19396	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	82	28	K	E	Aaa/Gaa	-6,01	0	0	benign	0,03	neutral	0,34	neutral	3,74	deleterious	-3,32	neutral	-1,83	low_impact	1,23	neutral	0,84	neutral	0,77	deleterious	0,44	6,95	0,48	0,55	NA	NA	disease	0,63	disease	0,51	neutral	0,49	0	neutral	0,64	deleterious	0,66	neutral	-6	neutral	0,21	medium_impact	0,69	medium_impact	0,07	medium_impact	-0,08	0,68	0,85	6,47	9,42	N	0,34	N	0,88	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12418	12418	A	C	MI.19397	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	82	28	K	Q	Aaa/Caa	-6,01	0	0	possibly_damaging	0,56	neutral	0,34	neutral	3,71	deleterious	-3,51	neutral	-1,72	low_impact	1,48	neutral	0,81	neutral	0,84	deleterious	0,09	3,52	0,55	0,6	NA	NA	neutral	0,41	neutral	0,26	neutral	0,2	6	neutral	0,66	neutral	0,39	neutral	-3	deleterious	0,44	medium_impact	-0,85	medium_impact	0,07	medium_impact	0,15	0,79	0,85	6,47	9,42	N	0,37	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12419	12419	A	T	MI.19398	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	83	28	K	M	aAa/aTa	0,18	0	0	probably_damaging	0,94	neutral	0,23	neutral	3,65	deleterious	-5,96	deleterious	-3,03	medium_impact	2,23	neutral	0,8	neutral	0,73	deleterious	3,63	23,2	0,29	0,45	NA	NA	neutral	0,4	neutral	0,29	neutral	0,22	6	neutral	0,96	neutral	0,15	deleterious	1	deleterious	0,69	low_impact	-1,88	medium_impact	-0,06	medium_impact	0,83	0,48	0,8	6,47	9,42	N	0,41	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12419	12419	A	C	MI.19399	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	83	28	K	T	aAa/aCa	0,18	0	0	possibly_damaging	0,64	neutral	0,43	neutral	3,71	neutral	-2,89	neutral	-2,13	low_impact	1,43	neutral	0,84	neutral	0,95	deleterious	0,69	8,76	0,35	0,5	NA	NA	neutral	0,46	neutral	0,28	neutral	0,27	5	neutral	0,65	neutral	0,4	neutral	-3	deleterious	0,52	medium_impact	-0,98	medium_impact	0,17	medium_impact	0,1	0,54	0,8	6,47	9,42	N	0,35	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8617	8617	A	G	MI.194	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	91	31	I	V	Atc/Gtc	-2,65	0	0	benign	0	neutral	0,35	neutral	4,42	neutral	0,31	neutral	-0,71	low_impact	1,18	neutral	0,88	neutral	0,89	neutral	-0,12	1,58	0,57	0,65	neutral	0,43	neutral	0,23	neutral	0,33	neutral	0,43	1	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,15	high_impact	2,09	medium_impact	0,14	medium_impact	-0,09	0,19	0,9	28,32	22,32	N	0,4	N	0	polymorphism	1	0,01	.	.	.	.	.	acute leukemia platelets, leukocytes & bone marrow	.	.	.	.	.	.	.	.	.
chrM	5932	5932	C	T	MI.1940	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	29	10	T	M	aCa/aTa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	-0,85	deleterious	-3,54	neutral	-0,96	high_impact	3,63	neutral	0,83	damaging	0,14	deleterious	3,82	23,4	0,27	0,55	disease	0,53	disease	0,83	disease	0,76	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	high_impact	2,25	0,68	0,9	2,34	6,72	N	0,47	N	0,95	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12420	12420	A	C	MI.19400	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	84	28	K	N	aaA/aaC	0,18	0	0	benign	0,03	neutral	0,36	neutral	3,7	deleterious	-4,13	neutral	-0,97	low_impact	1,88	neutral	0,81	neutral	0,92	deleterious	0,49	7,37	0,61	0,65	NA	NA	neutral	0,4	neutral	0,27	neutral	0,2	6	neutral	0,62	deleterious	0,67	neutral	-6	deleterious	0,52	medium_impact	0,69	medium_impact	0,1	medium_impact	0,51	0,68	0,85	6,47	9,42	N	0,44	N	0,68	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12420	12420	A	T	MI.19401	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	84	28	K	N	aaA/aaT	0,18	0	0	benign	0,03	neutral	0,36	neutral	3,7	deleterious	-4,13	neutral	-0,97	low_impact	1,88	neutral	0,81	neutral	0,92	deleterious	0,57	7,93	0,61	0,65	NA	NA	neutral	0,4	neutral	0,27	neutral	0,2	6	neutral	0,62	deleterious	0,67	neutral	-6	deleterious	0,52	medium_impact	0,69	medium_impact	0,1	medium_impact	0,51	0,68	0,85	6,47	9,42	N	0,44	N	0,68	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12421	12421	A	G	MI.19402	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	85	29	K	E	Aaa/Gaa	-8,53	0	0	benign	0,12	neutral	0,31	neutral	3,74	neutral	-0,08	neutral	-0,42	medium_impact	1,99	neutral	0,77	neutral	0,71	neutral	1,43	12,95	0,46	0,55	NA	NA	neutral	0,48	neutral	0,45	neutral	0,34	3	neutral	0,64	deleterious	0,6	neutral	-3	deleterious	0,73	medium_impact	0,08	medium_impact	0,04	medium_impact	0,62	0,71	0,85	25,87	13,49	N	0,39	N	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12421	12421	A	C	MI.19403	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	85	29	K	Q	Aaa/Caa	-8,53	0	0	benign	0,3	neutral	0,32	neutral	3,7	neutral	-0,89	neutral	-0,36	medium_impact	2,19	neutral	0,78	neutral	0,89	neutral	1,17	11,58	0,51	0,6	NA	NA	neutral	0,22	neutral	0,23	neutral	0,16	7	neutral	0,61	deleterious	0,51	neutral	-3	deleterious	0,69	medium_impact	-0,4	medium_impact	0,05	medium_impact	0,8	0,73	0,85	25,87	13,49	N	0,44	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12422	12422	A	T	MI.19404	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	86	29	K	M	aAa/aTa	-1,65	0	0	possibly_damaging	0,83	neutral	0,23	neutral	3,62	deleterious	-3,06	neutral	-1,36	low_impact	1,84	neutral	0,78	neutral	0,7	deleterious	2,3	18,14	0,36	0,5	NA	NA	neutral	0,25	neutral	0,31	neutral	0,17	7	neutral	0,89	neutral	0,2	neutral	-3	deleterious	0,7	low_impact	-1,4	medium_impact	-0,06	medium_impact	0,48	0,62	0,8	25,87	13,49	N	0,4	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12422	12422	A	C	MI.19405	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	86	29	K	T	aAa/aCa	-1,65	0	0	benign	0,01	neutral	0,42	neutral	3,69	neutral	1,28	neutral	0,5	low_impact	1,06	neutral	0,83	neutral	0,99	deleterious	0,79	9,41	0,35	0,5	NA	NA	neutral	0,25	neutral	0,26	neutral	0,18	6	neutral	0,57	deleterious	0,71	neutral	-6	deleterious	0,7	medium_impact	1,15	medium_impact	0,16	medium_impact	-0,23	0,66	0,8	25,87	13,49	N	0,43	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12423	12423	A	C	MI.19406	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	87	29	K	N	aaA/aaC	-6,24	0	0	benign	0	neutral	0,34	neutral	3,69	neutral	1,46	neutral	1,83	low_impact	0,97	neutral	0,84	neutral	0,99	neutral	1,25	11,99	0,54	0,6	NA	NA	neutral	0,24	neutral	0,28	neutral	0,17	7	neutral	0,66	deleterious	0,67	neutral	-6	deleterious	0,71	high_impact	2,1	medium_impact	0,07	medium_impact	-0,32	0,76	0,85	25,87	13,49	N	0,39	N	0,32	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12423	12423	A	T	MI.19407	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	87	29	K	N	aaA/aaT	-6,24	0	0	benign	0	neutral	0,34	neutral	3,69	neutral	1,46	neutral	1,83	low_impact	0,97	neutral	0,84	neutral	0,99	neutral	1,32	12,39	0,54	0,6	NA	NA	neutral	0,24	neutral	0,28	neutral	0,17	7	neutral	0,66	deleterious	0,67	neutral	-6	deleterious	0,71	high_impact	2,1	medium_impact	0,07	medium_impact	-0,32	0,76	0,85	25,87	13,49	N	0,4	N	0,32	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12424	12424	A	C	MI.19408	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	88	30	N	H	Aac/Cac	-7,61	0	0	benign	0	neutral	0,54	neutral	3,7	neutral	-2,27	neutral	-1,26	low_impact	1,16	neutral	0,86	neutral	0,85	neutral	1,18	11,65	0,83	0,85	NA	NA	neutral	0,35	neutral	0,31	neutral	0,2	6	neutral	0,45	deleterious	0,77	neutral	-6	deleterious	0,61	high_impact	2,1	medium_impact	0,27	medium_impact	-0,14	0,6	0,8	29,52	15,35	N	0,33	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12424	12424	A	G	MI.19409	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	88	30	N	D	Aac/Gac	-7,61	0	0	benign	0,05	neutral	0,25	neutral	3,75	neutral	-1,16	neutral	-1,65	low_impact	1,64	neutral	0,85	neutral	0,86	neutral	-0,19	1,16	0,9	0,9	NA	NA	neutral	0,22	neutral	0,28	neutral	0,19	6	neutral	0,73	deleterious	0,6	neutral	-6	neutral	0,3	medium_impact	0,47	medium_impact	-0,03	medium_impact	0,3	0,61	0,8	29,52	15,35	N	0,47	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5934	5934	A	C	MI.1941	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	31	11	N	H	Aac/Cac	-8,9	0	0	probably_damaging	1	deleterious	0	neutral	-0,99	deleterious	-3	neutral	-0,84	medium_impact	3,25	damaging	0,54	neutral	0,35	deleterious	2,88	21,8	0,39	0,55	disease	0,76	disease	0,81	disease	0,72	disease	0,75	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	medium_impact	1,9	0,38	0,9	2,92	7,08	N	0,35	N	0,52	polymorphism	0,97	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12424	12424	A	T	MI.19410	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	88	30	N	Y	Aac/Tac	-7,61	0	0	benign	0	neutral	1	neutral	3,67	neutral	-0,99	neutral	-2,09	low_impact	1,84	neutral	0,9	neutral	0,82	deleterious	1,87	15,43	0,62	0,65	NA	NA	disease	0,55	neutral	0,36	disease	0,51	0	neutral	0	deleterious	1	neutral	-6	deleterious	0,66	high_impact	2,1	high_impact	1,89	medium_impact	0,48	0,74	0,85	29,52	15,35	N	0,23	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12425	12425	A	G	MI.19411	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	89	30	N	S	aAc/aGc	-0,27	0	0	benign	0	neutral	0,46	neutral	3,76	neutral	-0,02	neutral	-0,74	low_impact	0,95	neutral	0,89	neutral	1	neutral	-1,09	0,01	0,81	0,85	NA	NA	neutral	0,32	neutral	0,42	neutral	0,17	7	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,13	high_impact	2,1	medium_impact	0,19	medium_impact	-0,34	0,47	0,8	29,52	15,35	N	0,36	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12425	12425	A	C	MI.19412	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	89	30	N	T	aAc/aCc	-0,27	0	0	benign	0	neutral	0,44	neutral	3,74	neutral	-0,71	neutral	-0,57	neutral_impact	0,74	neutral	0,86	neutral	0,98	neutral	-0,72	0,07	0,75	0,8	NA	NA	neutral	0,33	neutral	0,23	neutral	0,2	6	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,25	high_impact	2,1	medium_impact	0,18	medium_impact	-0,53	0,67	0,85	29,52	15,35	N	0,41	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12425	12425	A	T	MI.19413	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	89	30	N	I	aAc/aTc	-0,27	0	0	benign	0	neutral	0,43	neutral	3,68	neutral	-2,63	neutral	-2,46	low_impact	1,84	neutral	0,86	neutral	0,91	deleterious	1,83	15,16	0,59	0,65	NA	NA	neutral	0,49	neutral	0,45	neutral	0,41	2	neutral	0,56	deleterious	0,72	neutral	-6	deleterious	0,59	high_impact	2,1	medium_impact	0,17	medium_impact	0,48	0,52	0,8	29,52	15,35	N	0,37	N	0,14	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12426	12426	C	A	MI.19414	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	90	30	N	K	aaC/aaA	-2,34	0	0	benign	0,05	neutral	0,37	neutral	3,81	neutral	1,54	neutral	-0,24	neutral_impact	0,46	neutral	0,88	neutral	0,95	deleterious	0,22	4,92	0,84	0,85	NA	NA	neutral	0,32	neutral	0,22	neutral	0,2	6	neutral	0,6	deleterious	0,66	neutral	-6	neutral	0,34	medium_impact	0,47	medium_impact	0,11	medium_impact	-0,78	0,64	0,8	29,52	15,35	N	0,43	N	0,19	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12426	12426	C	G	MI.19415	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	90	30	N	K	aaC/aaG	-2,34	0	0	benign	0,05	neutral	0,37	neutral	3,81	neutral	1,54	neutral	-0,24	neutral_impact	0,46	neutral	0,88	neutral	0,95	neutral	-0,18	1,21	0,84	0,85	NA	NA	neutral	0,32	neutral	0,22	neutral	0,2	6	neutral	0,6	deleterious	0,66	neutral	-6	neutral	0,34	medium_impact	0,47	medium_impact	0,11	medium_impact	-0,78	0,64	0,8	29,52	15,35	N	0,42	N	0,19	polymorphism	1	0	rs386829158	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12427	12427	T	G	MI.19416	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	91	31	S	A	Tca/Gca	-12,66	0	0	benign	0,05	neutral	0,53	neutral	3,8	neutral	-0,83	neutral	-0,99	low_impact	1,58	neutral	0,83	neutral	0,88	neutral	-0,17	1,26	0,45	0,55	NA	NA	neutral	0,1	neutral	0,29	neutral	0,23	5	neutral	0,41	deleterious	0,74	neutral	-6	neutral	0,21	medium_impact	0,47	medium_impact	0,26	medium_impact	0,24	0,56	0,8	29,19	16,74	N	0,36	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12427	12427	T	C	MI.19417	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	91	31	S	P	Tca/Cca	-12,66	0	0	benign	0	neutral	0,24	neutral	3,71	neutral	-2,06	neutral	-1,44	low_impact	1,3	neutral	0,84	neutral	0,81	deleterious	2,25	17,81	0,31	0,45	NA	NA	neutral	0,45	neutral	0,17	neutral	0,2	6	neutral	0,76	deleterious	0,62	neutral	-6	deleterious	0,65	high_impact	2,1	medium_impact	-0,04	medium_impact	-0,02	0,41	0,8	29,19	16,74	N	0,48	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12427	12427	T	A	MI.19418	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	91	31	S	T	Tca/Aca	-12,66	0	0	benign	0,01	neutral	0,41	neutral	3,77	neutral	-0,77	neutral	-0,35	low_impact	1,38	neutral	0,85	neutral	0,97	deleterious	0,3	5,66	0,41	0,5	NA	NA	neutral	0,11	neutral	0,15	neutral	0,23	5	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,29	medium_impact	1,15	medium_impact	0,15	medium_impact	0,06	0,61	0,8	29,19	16,74	N	0,53	P	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12428	12428	C	G	MI.19419	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	92	31	S	W	tCa/tGa	-6,24	0	0	possibly_damaging	0,77	neutral	0,19	neutral	3,7	deleterious	-4,69	deleterious	-2,68	low_impact	1,58	neutral	0,77	neutral	0,84	deleterious	2,67	20,6	0,25	0,45	NA	NA	neutral	0,16	neutral	0,49	neutral	0,23	6	neutral	0,87	neutral	0,21	neutral	-3	deleterious	0,64	low_impact	-1,24	medium_impact	-0,12	medium_impact	0,24	0,5	0,8	29,19	16,74	N	0,42	N	0,49	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5934	5934	A	G	MI.1942	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	31	11	N	D	Aac/Gac	-8,9	0	0	probably_damaging	0,98	neutral	0,06	neutral	-0,95	neutral	1,31	neutral	-0,84	low_impact	0,89	damaging	0,52	neutral	0,44	deleterious	3,69	23,3	0,6	0,65	neutral	0,16	disease	0,78	disease	0,57	disease	0,69	4	deleterious	0,99	neutral	0,04	neutral	-2	deleterious	0,71	low_impact	-2,35	medium_impact	-0,47	medium_impact	-0,28	0,55	0,9	2,92	7,08	N	0,4	N	0,78	polymorphism	0,98	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12428	12428	C	T	MI.19420	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	92	31	S	L	tCa/tTa	-6,24	0	0	benign	0	neutral	0,69	neutral	3,75	neutral	1,45	neutral	-0,94	neutral_impact	0,61	neutral	0,86	neutral	0,98	deleterious	0,4	6,62	0,37	0,5	NA	NA	neutral	0,21	neutral	0,35	neutral	0,16	7	neutral	0,3	deleterious	0,85	neutral	-6	neutral	0,09	high_impact	2,1	medium_impact	0,42	medium_impact	-0,65	0,7	0,85	29,19	16,74	N	0,42	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12430	12430	T	G	MI.19421	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	94	32	Y	D	Tac/Gac	-3,71	0	0	probably_damaging	1	neutral	0,24	neutral	3,75	deleterious	-10,19	deleterious	-8,57	medium_impact	2,89	neutral	0,71	damaging	0,25	deleterious	3,74	23,3	0,43	0,55	NA	NA	disease	0,53	neutral	0,44	disease	0,5	0	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,04	medium_impact	1,44	0,42	0,8	14,1	12,81	N	0,32	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12430	12430	T	A	MI.19422	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	94	32	Y	N	Tac/Aac	-3,71	0	0	probably_damaging	1	neutral	0,38	neutral	3,77	deleterious	-9,1	deleterious	-7,84	medium_impact	2,54	neutral	0,73	neutral	0,43	deleterious	2,78	21,3	0,48	0,55	NA	NA	neutral	0,42	neutral	0,29	neutral	0,2	6	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,12	medium_impact	1,12	0,25	0,8	14,1	12,81	N	0,35	N	0,9	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12430	12430	T	C	MI.19423	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	94	32	Y	H	Tac/Cac	-3,71	0	0	probably_damaging	1	neutral	0,54	neutral	3,76	deleterious	-7,81	deleterious	-4,57	medium_impact	2,54	neutral	0,73	neutral	0,43	deleterious	2,22	17,63	0,55	0,6	NA	NA	neutral	0,27	neutral	0,28	neutral	0,2	6	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,27	medium_impact	1,12	0,36	0,8	14,1	12,81	N	0,31	N	0,75	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12431	12431	A	G	MI.19424	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	95	32	Y	C	tAc/tGc	1,1	0	0	probably_damaging	1	neutral	0,17	neutral	3,74	deleterious	-10,48	deleterious	-7,73	medium_impact	2,89	neutral	0,65	damaging	0,2	deleterious	3,19	22,7	0,36	0,5	NA	NA	disease	0,53	neutral	0,48	disease	0,51	0	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,15	medium_impact	1,44	0,13	0,8	14,1	12,81	N	0,33	N	0,92	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12431	12431	A	C	MI.19425	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	95	32	Y	S	tAc/tCc	1,1	0	0	probably_damaging	1	neutral	0,48	neutral	3,8	deleterious	-8,94	deleterious	-7,64	medium_impact	2,54	neutral	0,75	neutral	0,51	deleterious	2,29	18,07	0,27	0,45	NA	NA	neutral	0,38	neutral	0,45	neutral	0,15	7	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,21	medium_impact	1,12	0,31	0,8	14,1	12,81	N	0,37	N	0,9	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12431	12431	A	T	MI.19426	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	95	32	Y	F	tAc/tTc	1,1	0	0	probably_damaging	1	neutral	0,74	neutral	3,8	deleterious	-5,07	neutral	-2,11	medium_impact	2,08	neutral	0,81	neutral	0,93	neutral	1,05	10,93	0,49	0,55	NA	NA	neutral	0,17	neutral	0,21	neutral	0,22	6	deleterious	0,99	neutral	0,37	deleterious	1	deleterious	0,7	low_impact	-3,6	medium_impact	0,48	medium_impact	0,7	0,24	0,8	14,1	12,81	N	0,3	N	0,2	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12433	12433	C	G	MI.19427	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	97	33	P	A	Ccc/Gcc	-5,55	0	0	probably_damaging	1	neutral	0,56	neutral	3,83	deleterious	-4,89	deleterious	-6,24	low_impact	1,61	neutral	0,8	neutral	0,51	neutral	1,52	13,41	0,33	0,5	disease	0,67	neutral	0,19	neutral	0,3	neutral	0,45	1	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,29	medium_impact	0,27	0,77	0,85	11,11	14,64	N	0,25	N	0,71	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12433	12433	C	A	MI.19428	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	97	33	P	T	Ccc/Acc	-5,55	0	0	probably_damaging	1	neutral	0,44	neutral	3,8	deleterious	-6,05	deleterious	-6,2	medium_impact	2,53	neutral	0,75	neutral	0,34	deleterious	2,36	18,55	0,39	0,5	disease	0,73	neutral	0,41	neutral	0,17	disease	0,66	3	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,18	medium_impact	1,11	0,66	0,8	11,11	14,64	N	0,36	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12433	12433	C	T	MI.19429	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	97	33	P	S	Ccc/Tcc	-5,55	0	0	probably_damaging	1	neutral	0,46	neutral	3,82	deleterious	-5,36	deleterious	-6,05	medium_impact	2,38	neutral	0,8	neutral	0,8	deleterious	2,49	19,43	0,42	0,55	disease	0,67	neutral	0,45	neutral	0,3	disease	0,63	3	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,19	medium_impact	0,97	0,35	0,8	11,11	14,64	N	0,34	N	0,75	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5934	5934	A	T	MI.1943	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	31	11	N	Y	Aac/Tac	-8,9	0	0	probably_damaging	1	deleterious	0	neutral	-0,99	deleterious	-5,03	neutral	-1,35	high_impact	4,15	damaging	0,55	neutral	0,37	deleterious	3,54	23,1	0,3	0,55	disease	0,86	disease	0,88	disease	0,72	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,73	0,37	0,9	2,92	7,08	N	0,34	N	0,83	polymorphism	0,88	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12434	12434	C	G	MI.19430	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	98	33	P	R	cCc/cGc	-0,5	0	0	probably_damaging	1	neutral	0,38	neutral	3,79	deleterious	-6,82	deleterious	-7,27	medium_impact	2,73	neutral	0,7	damaging	0,21	deleterious	3,39	23	0,38	0,5	disease	0,64	disease	0,57	neutral	0,46	disease	0,53	1	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,12	medium_impact	1,29	0,65	0,8	11,11	14,64	N	0,28	N	0,69	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12434	12434	C	A	MI.19431	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	98	33	P	H	cCc/cAc	-0,5	0	0	probably_damaging	1	neutral	0,55	neutral	3,74	deleterious	-8,01	deleterious	-7,36	medium_impact	2,73	neutral	0,76	neutral	0,31	deleterious	3,82	23,4	0,37	0,5	disease	0,82	neutral	0,46	neutral	0,29	disease	0,66	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,28	medium_impact	1,29	0,55	0,8	11,11	14,64	N	0,29	N	0,73	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12434	12434	C	T	MI.19432	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	98	33	P	L	cCc/cTc	-0,5	0	0	probably_damaging	1	neutral	0,68	neutral	3,78	deleterious	-7,24	deleterious	-8,05	medium_impact	2,19	neutral	0,83	neutral	0,91	deleterious	2,88	21,8	0,36	0,5	disease	0,81	neutral	0,36	neutral	0,37	disease	0,67	3	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,41	medium_impact	0,8	0,8	0,85	11,11	14,64	N	0,34	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12436	12436	C	G	MI.19433	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	100	34	H	D	Cat/Gat	-9,22	0	0	benign	0,01	neutral	0,23	neutral	3,79	neutral	0,78	neutral	-2,04	low_impact	1,09	neutral	0,82	neutral	0,83	neutral	1,63	14,04	0,32	0,5	neutral	0,37	neutral	0,36	disease	0,53	neutral	0,48	0	neutral	0,77	deleterious	0,61	neutral	-6	deleterious	0,68	medium_impact	1,15	medium_impact	-0,06	medium_impact	-0,21	0,46	0,8	29,52	18,37	N	0,34	N	0,1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12436	12436	C	A	MI.19434	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	100	34	H	N	Cat/Aat	-9,22	0	0	benign	0	neutral	0,33	neutral	3,81	neutral	1,63	neutral	-0,4	neutral_impact	0,78	neutral	0,9	neutral	0,93	neutral	1,71	14,48	0,62	0,65	neutral	0,4	neutral	0,22	neutral	0,28	neutral	0,4	2	neutral	0,67	deleterious	0,67	neutral	-6	deleterious	0,65	high_impact	2,1	medium_impact	0,06	medium_impact	-0,49	0,55	0,8	29,52	18,37	N	0,44	N	0,32	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12436	12436	C	T	MI.19435	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	100	34	H	Y	Cat/Tat	-9,22	0	0	benign	0	neutral	1	neutral	3,76	neutral	2,11	neutral	-1,3	neutral_impact	0,6	neutral	0,87	neutral	0,93	deleterious	1,93	15,8	0,64	0,7	disease	0,5	neutral	0,28	neutral	0,19	neutral	0,22	6	neutral	0	deleterious	1	neutral	-6	deleterious	0,69	high_impact	2,1	high_impact	1,89	medium_impact	-0,66	0,38	0,8	29,52	18,37	N	0,38	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12437	12437	A	C	MI.19436	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	101	34	H	P	cAt/cCt	-8,99	0	0	possibly_damaging	0,5	neutral	0,22	neutral	3,75	neutral	-0,22	deleterious	-2,94	medium_impact	2,19	neutral	0,84	neutral	0,8	neutral	1,56	13,65	0,25	0,45	disease	0,66	disease	0,6	neutral	0,48	neutral	0,5	0	neutral	0,76	neutral	0,36	NA	0	deleterious	0,81	medium_impact	-0,75	medium_impact	-0,07	medium_impact	0,8	0,35	0,8	29,52	18,37	N	0,33	N	0,64	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12437	12437	A	T	MI.19437	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	101	34	H	L	cAt/cTt	-8,99	0	0	benign	0,18	neutral	0,66	neutral	3,81	neutral	2,15	deleterious	-3,06	low_impact	1,15	neutral	0,82	neutral	0,98	deleterious	1,93	15,79	0,38	0,5	neutral	0,28	neutral	0,27	neutral	0,41	neutral	0,42	2	neutral	0,22	deleterious	0,74	neutral	-6	deleterious	0,64	medium_impact	-0,12	medium_impact	0,39	medium_impact	-0,15	0,28	0,8	29,52	18,37	N	0,38	N	0,09	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12437	12437	A	G	MI.19438	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	101	34	H	R	cAt/cGt	-8,99	0	0	benign	0,24	neutral	0,37	neutral	3,83	neutral	0,71	neutral	-1,72	medium_impact	2,19	neutral	0,85	neutral	0,65	deleterious	0,84	9,71	0,73	0,75	disease	0,54	neutral	0,27	neutral	0,4	neutral	0,42	2	neutral	0,55	deleterious	0,57	neutral	-3	deleterious	0,71	medium_impact	-0,27	medium_impact	0,11	medium_impact	0,8	0,46	0,8	29,52	18,37	N	0,34	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12438	12438	T	G	MI.19439	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	102	34	H	Q	caT/caG	-7,16	0	0	benign	0,3	neutral	0,32	neutral	3,81	neutral	2,37	neutral	-0,91	low_impact	0,84	neutral	0,82	neutral	0,98	neutral	1,25	12,02	0,67	0,7	disease	0,54	neutral	0,2	neutral	0,44	neutral	0,38	2	neutral	0,61	deleterious	0,51	neutral	-6	deleterious	0,69	medium_impact	-0,4	medium_impact	0,05	medium_impact	-0,44	0,59	0,8	29,52	18,37	N	0,38	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5935	5935	A	T	MI.1944	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	32	11	N	I	aAc/aTc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	-0,99	deleterious	-4,94	neutral	-1,52	high_impact	3,6	damaging	0,54	neutral	0,5	deleterious	3,63	23,2	0,27	0,55	disease	0,85	disease	0,9	disease	0,68	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,23	0,29	0,9	2,92	7,08	P	0,53	P	0,86	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12438	12438	T	A	MI.19440	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	102	34	H	Q	caT/caA	-7,16	0	0	benign	0,3	neutral	0,32	neutral	3,81	neutral	2,37	neutral	-0,91	low_impact	0,84	neutral	0,82	neutral	0,98	neutral	1,34	12,46	0,67	0,7	disease	0,54	neutral	0,2	neutral	0,44	neutral	0,38	2	neutral	0,61	deleterious	0,51	neutral	-6	deleterious	0,69	medium_impact	-0,4	medium_impact	0,05	medium_impact	-0,44	0,59	0,8	29,52	18,37	N	0,39	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12439	12439	T	C	MI.19441	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	103	35	Y	H	Tat/Cat	-8,99	0	0	benign	0,07	neutral	0,57	neutral	3,76	deleterious	-4,01	deleterious	-2,57	low_impact	1,7	neutral	0,79	neutral	0,92	neutral	1,32	12,37	0,52	0,6	disease	0,59	neutral	0,12	neutral	0,27	neutral	0,28	4	neutral	0,36	deleterious	0,75	neutral	-6	deleterious	0,72	medium_impact	0,32	medium_impact	0,3	medium_impact	0,35	0,54	0,8	6,97	9,53	N	0,34	N	0,98	polymorphism	1	0,06	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	12439	12439	T	A	MI.19442	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	103	35	Y	N	Tat/Aat	-8,99	0	0	possibly_damaging	0,81	neutral	0,48	neutral	3,77	deleterious	-8,02	deleterious	-6,79	medium_impact	2,25	neutral	0,78	neutral	0,84	deleterious	3,94	23,5	0,4	0,5	disease	0,66	neutral	0,46	neutral	0,38	disease	0,63	3	neutral	0,79	neutral	0,34	NA	0	deleterious	0,76	low_impact	-1,34	medium_impact	0,21	medium_impact	0,85	0,36	0,8	6,97	9,53	N	0,35	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12439	12439	T	G	MI.19443	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	103	35	Y	D	Tat/Gat	-8,99	0	0	possibly_damaging	0,89	neutral	0,43	neutral	3,76	deleterious	-8,88	deleterious	-7,92	medium_impact	2,4	neutral	0,77	neutral	0,65	deleterious	3,72	23,3	0,32	0,5	disease	0,76	disease	0,59	disease	0,68	disease	0,68	4	neutral	0,89	neutral	0,27	NA	0	deleterious	0,8	low_impact	-1,61	medium_impact	0,17	medium_impact	0,99	0,51	0,8	6,97	9,53	N	0,3	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12440	12440	A	C	MI.19444	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	104	35	Y	S	tAt/tCt	-0,5	0	0	possibly_damaging	0,85	neutral	0,66	neutral	3,81	deleterious	-7,82	deleterious	-7,09	medium_impact	2,13	neutral	0,8	neutral	0,84	deleterious	3,53	23,1	0,34	0,5	neutral	0,49	neutral	0,43	disease	0,55	neutral	0,46	1	neutral	0,83	neutral	0,41	NA	0	deleterious	0,75	low_impact	-1,46	medium_impact	0,39	medium_impact	0,74	0,46	0,8	6,97	9,53	N	0,32	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12440	12440	A	G	MI.19445	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	104	35	Y	C	tAt/tGt	-0,5	0	0	probably_damaging	0,96	neutral	0,2	neutral	3,73	deleterious	-9,53	deleterious	-7,39	medium_impact	2,94	neutral	0,7	neutral	0,53	deleterious	3,34	22,9	0,41	0,5	disease	0,69	disease	0,61	neutral	0,4	disease	0,51	0	neutral	0,97	neutral	0,12	deleterious	1	deleterious	0,77	low_impact	-2,06	medium_impact	-0,1	medium_impact	1,48	0,2	0,8	6,97	9,53	N	0,38	N	1	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12440	12440	A	T	MI.19446	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	104	35	Y	F	tAt/tTt	-0,5	0	0	possibly_damaging	0,74	neutral	0,71	neutral	3,79	deleterious	-4,59	deleterious	-3,35	medium_impact	2,4	neutral	0,77	neutral	0,81	deleterious	3,12	22,6	0,5	0,6	neutral	0,49	neutral	0,35	neutral	0,27	neutral	0,43	2	neutral	0,69	deleterious	0,49	NA	0	deleterious	0,71	low_impact	-1,18	medium_impact	0,45	medium_impact	0,99	0,4	0,8	6,97	9,53	N	0,29	N	0,8	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12442	12442	G	C	MI.19447	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	106	36	V	L	Gta/Cta	-11,05	0	0	benign	0,31	neutral	0,86	neutral	3,74	deleterious	-5,18	neutral	-2,45	medium_impact	2,53	neutral	0,7	neutral	0,62	neutral	1,54	13,54	0,5	0,6	neutral	0,25	disease	0,67	disease	0,54	disease	0,58	2	neutral	0,2	deleterious	0,78	neutral	-3	neutral	0,4	medium_impact	-0,42	medium_impact	0,67	medium_impact	1,11	0,75	0,85	23,71	17,6	N	0,3	N	0,55	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12442	12442	G	A	MI.19448	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	106	36	V	M	Gta/Ata	-11,05	0	0	probably_damaging	0,94	neutral	0,31	neutral	3,61	deleterious	-7,17	neutral	-2,46	medium_impact	2,73	neutral	0,78	neutral	0,7	deleterious	3,39	23	0,44	0,55	neutral	0,41	disease	0,58	neutral	0,25	neutral	0,48	0	neutral	0,95	neutral	0,19	deleterious	1	deleterious	0,66	low_impact	-1,88	medium_impact	0,04	medium_impact	1,29	0,79	0,85	23,71	17,6	N	0,37	N	0,6	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12442	12442	G	T	MI.19449	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	106	36	V	L	Gta/Tta	-11,05	0	0	benign	0,31	neutral	0,86	neutral	3,74	deleterious	-5,18	neutral	-2,45	medium_impact	2,53	neutral	0,7	neutral	0,62	neutral	1,65	14,12	0,5	0,6	neutral	0,25	disease	0,67	disease	0,54	disease	0,58	2	neutral	0,2	deleterious	0,78	neutral	-3	neutral	0,4	medium_impact	-0,42	medium_impact	0,67	medium_impact	1,11	0,75	0,85	23,71	17,6	N	0,3	N	0,55	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5935	5935	A	G	MI.1945	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	32	11	N	S	aAc/aGc	8,69	1	0	probably_damaging	0,94	neutral	0,05	neutral	-0,96	neutral	-2,18	neutral	-0,84	medium_impact	2,56	damaging	0,47	neutral	0,49	deleterious	2,78	21,3	0,51	0,6	neutral	0,49	disease	0,74	disease	0,6	disease	0,56	1	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,79	low_impact	-1,88	medium_impact	-0,52	medium_impact	1,27	0,28	0,9	2,92	7,08	P	0,7	P	0,17	disease_causing	1	0,03	.	.	.	.	.	.	.	.	0,15	A5935G	Prostate Cancer	+	-	Reported	1
chrM	12443	12443	T	A	MI.19450	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	107	36	V	E	gTa/gAa	0,41	0	0	possibly_damaging	0,74	neutral	0,29	neutral	3,58	deleterious	-9,06	deleterious	-5,2	medium_impact	3,08	neutral	0,71	neutral	0,46	deleterious	2,71	20,9	0,13	0,4	disease	0,71	disease	0,86	disease	0,71	disease	0,78	6	neutral	0,8	neutral	0,28	NA	0	deleterious	0,69	low_impact	-1,18	medium_impact	0,02	medium_impact	1,61	0,62	0,8	23,71	17,6	N	0,32	N	0,95	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12443	12443	T	G	MI.19451	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	107	36	V	G	gTa/gGa	0,41	0	0	possibly_damaging	0,56	neutral	0,32	neutral	3,59	deleterious	-8,82	deleterious	-6,17	medium_impact	3,08	neutral	0,67	neutral	0,6	neutral	1,74	14,65	0,17	0,45	disease	0,69	disease	0,79	disease	0,62	disease	0,7	4	neutral	0,68	neutral	0,38	NA	0	deleterious	0,56	medium_impact	-0,85	medium_impact	0,05	medium_impact	1,61	0,62	0,8	23,71	17,6	N	0,32	N	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12443	12443	T	C	MI.19452	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	107	36	V	A	gTa/gCa	0,41	0	0	benign	0,02	neutral	0,55	neutral	3,69	deleterious	-6,63	deleterious	-3,36	medium_impact	3,08	neutral	0,79	neutral	0,8	deleterious	0,31	5,8	0,38	0,5	neutral	0,43	neutral	0,39	neutral	0,29	neutral	0,46	1	neutral	0,42	deleterious	0,77	neutral	-3	neutral	0,2	medium_impact	0,86	medium_impact	0,28	medium_impact	1,61	0,56	0,8	23,71	17,6	N	0,39	N	0,37	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12445	12445	A	G	MI.19453	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	109	37	K	E	Aaa/Gaa	-5,78	0	0	probably_damaging	1	neutral	0,34	neutral	3,69	deleterious	-6,4	deleterious	-3,51	medium_impact	2,52	neutral	0,72	neutral	0,3	deleterious	3,79	23,4	0,35	0,5	disease	0,58	disease	0,86	disease	0,75	disease	0,79	6	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,07	medium_impact	1,1	0,65	0,8	11,28	13,79	N	0,28	N	0,75	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12445	12445	A	C	MI.19454	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	109	37	K	Q	Aaa/Caa	-5,78	0	0	probably_damaging	1	neutral	0,31	neutral	3,66	deleterious	-6,26	deleterious	-3,51	medium_impact	2,87	neutral	0,73	damaging	0,21	deleterious	3,21	22,7	0,41	0,5	disease	0,61	disease	0,79	disease	0,52	disease	0,66	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,04	medium_impact	1,42	0,66	0,8	11,28	13,79	N	0,28	N	0,71	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12446	12446	A	C	MI.19455	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	110	37	K	T	aAa/aCa	1,79	0	0	probably_damaging	1	neutral	0,58	neutral	3,7	deleterious	-6	deleterious	-4,75	medium_impact	2,06	neutral	0,8	neutral	0,85	deleterious	2,24	17,8	0,32	0,5	neutral	0,37	disease	0,62	neutral	0,35	neutral	0,44	1	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,31	medium_impact	0,68	0,44	0,8	11,28	13,79	N	0,29	N	0,46	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12446	12446	A	T	MI.19456	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	110	37	K	M	aAa/aTa	1,79	0	0	probably_damaging	1	neutral	0,27	neutral	3,63	deleterious	-8,64	deleterious	-5,17	medium_impact	2,66	neutral	0,71	damaging	0,19	deleterious	3,61	23,2	0,27	0,45	neutral	0,48	disease	0,77	neutral	0,36	disease	0,58	2	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	-0,01	medium_impact	1,23	0,41	0,8	11,28	13,79	N	0,33	N	0,82	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12447	12447	A	T	MI.19457	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	111	37	K	N	aaA/aaT	1,1	0	0	probably_damaging	1	neutral	0,4	neutral	3,65	deleterious	-6,89	deleterious	-4,23	medium_impact	3,21	neutral	0,69	damaging	0,22	deleterious	3,67	23,3	0,52	0,6	disease	0,63	disease	0,81	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,14	medium_impact	1,73	0,65	0,8	11,28	13,79	N	0,28	N	0,64	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12447	12447	A	C	MI.19458	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	111	37	K	N	aaA/aaC	1,1	0	0	probably_damaging	1	neutral	0,4	neutral	3,65	deleterious	-6,89	deleterious	-4,23	medium_impact	3,21	neutral	0,69	damaging	0,22	deleterious	3,6	23,2	0,52	0,6	disease	0,63	disease	0,81	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,14	medium_impact	1,73	0,65	0,8	11,28	13,79	N	0,28	N	0,64	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12448	12448	T	A	MI.19459	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	112	38	S	T	Tcc/Acc	-0,27	0	0	benign	0	neutral	0,5	neutral	3,81	neutral	3,11	neutral	1,39	neutral_impact	-1,3	neutral	0,87	neutral	0,99	neutral	-0,88	0,03	0,39	0,5	neutral	0,24	neutral	0,04	neutral	0,17	neutral	0,22	6	neutral	0,5	deleterious	0,75	neutral	-6	neutral	0,09	high_impact	2,1	medium_impact	0,23	low_impact	-2,39	0,86	0,9	21,56	14,65	N	0,48	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5935	5935	A	C	MI.1946	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	32	11	N	T	aAc/aCc	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	-0,97	deleterious	-3,19	neutral	-1,01	high_impact	3,6	damaging	0,45	neutral	0,45	deleterious	3,12	22,5	0,34	0,55	disease	0,66	disease	0,8	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,64	low_impact	-1,48	high_impact	2,23	0,53	0,9	2,92	7,08	P	0,62	P	0,49	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12448	12448	T	C	MI.19460	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	112	38	S	P	Tcc/Ccc	-0,27	0	0	benign	0,19	neutral	0,24	neutral	3,68	neutral	-2,76	neutral	-2,46	low_impact	1,32	damaging	0,59	neutral	0,55	deleterious	2,05	16,53	0,22	0,45	disease	0,65	disease	0,71	disease	0,67	disease	0,74	5	neutral	0,72	deleterious	0,53	neutral	-6	deleterious	0,54	medium_impact	-0,15	medium_impact	-0,04	medium_impact	0	0,81	0,85	21,56	14,65	N	0,29	N	0,7	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12448	12448	T	G	MI.19461	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	112	38	S	A	Tcc/Gcc	-0,27	0	0	benign	0,02	neutral	0,56	neutral	3,77	neutral	-0,71	neutral	-1,31	low_impact	1,66	neutral	0,78	neutral	0,84	neutral	1,6	13,85	0,53	0,6	neutral	0,37	neutral	0,18	neutral	0,49	neutral	0,29	4	neutral	0,41	deleterious	0,77	neutral	-6	neutral	0,16	medium_impact	0,86	medium_impact	0,29	medium_impact	0,31	0,75	0,85	21,56	14,65	N	0,34	N	0,21	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12449	12449	C	G	MI.19462	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	113	38	S	C	tCc/tGc	-0,73	0	0	possibly_damaging	0,57	neutral	0,19	neutral	3,66	deleterious	-3,57	neutral	-2,35	low_impact	1,66	neutral	0,68	neutral	0,5	deleterious	3,04	22,4	0,33	0,5	disease	0,77	disease	0,51	disease	0,53	disease	0,64	3	neutral	0,81	neutral	0,31	neutral	-3	deleterious	0,65	medium_impact	-0,86	medium_impact	-0,12	medium_impact	0,31	0,78	0,85	21,56	14,65	N	0,34	N	0,64	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12449	12449	C	T	MI.19463	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	113	38	S	F	tCc/tTc	-0,73	0	0	benign	0,08	neutral	0,74	neutral	3,68	neutral	-2,92	deleterious	-2,88	low_impact	1,32	neutral	0,69	neutral	0,55	deleterious	2,09	16,79	0,29	0,45	neutral	0,41	disease	0,63	disease	0,57	disease	0,73	5	neutral	0,16	deleterious	0,83	neutral	-6	neutral	0,37	medium_impact	0,26	medium_impact	0,48	medium_impact	0	0,45	0,8	21,56	14,65	N	0,24	N	0,93	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12449	12449	C	A	MI.19464	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	113	38	S	Y	tCc/tAc	-0,73	0	0	benign	0,29	neutral	1	neutral	3,67	deleterious	-3,08	deleterious	-2,9	low_impact	1,66	neutral	0,74	neutral	0,74	deleterious	2,32	18,29	0,26	0,45	disease	0,63	disease	0,54	neutral	0,5	neutral	0,5	0	neutral	0,29	deleterious	0,86	neutral	-6	deleterious	0,58	medium_impact	-0,38	high_impact	1,89	medium_impact	0,31	0,75	0,85	21,56	14,65	N	0,22	N	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12451	12451	A	G	MI.19465	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	115	39	I	V	Att/Gtt	-7,84	0	0	benign	0	neutral	0,53	neutral	3,76	neutral	0,52	neutral	0,12	low_impact	1,7	neutral	0,81	neutral	0,85	deleterious	0,86	9,84	0,6	0,65	neutral	0,38	neutral	0,21	neutral	0,49	neutral	0,39	2	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,26	medium_impact	0,35	0,64	0,8	19,9	12,29	N	0,33	N	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12451	12451	A	C	MI.19466	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	115	39	I	L	Att/Ctt	-7,84	0	0	benign	0,02	neutral	0,7	neutral	3,76	neutral	0,06	neutral	-0,09	low_impact	1,7	neutral	0,79	neutral	0,78	neutral	1,63	14,02	0,33	0,5	neutral	0,22	neutral	0,31	neutral	0,35	neutral	0,45	1	neutral	0,26	deleterious	0,84	neutral	-6	neutral	0,14	medium_impact	0,86	medium_impact	0,44	medium_impact	0,35	0,74	0,85	19,9	12,29	N	0,32	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12451	12451	A	T	MI.19467	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	115	39	I	F	Att/Ttt	-7,84	0	0	benign	0,33	neutral	0,73	neutral	3,65	neutral	-1,34	neutral	-1,25	low_impact	1,7	neutral	0,67	neutral	0,67	deleterious	2,07	16,68	0,36	0,5	disease	0,59	disease	0,56	neutral	0,39	disease	0,51	0	neutral	0,24	deleterious	0,7	neutral	-6	deleterious	0,44	medium_impact	-0,45	medium_impact	0,47	medium_impact	0,35	0,75	0,85	19,9	12,29	N	0,22	N	0,23	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12452	12452	T	G	MI.19468	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	116	39	I	S	aTt/aGt	-0,96	0	0	benign	0,08	neutral	0,47	neutral	3,64	neutral	0,25	neutral	1,09	neutral_impact	0,66	neutral	0,82	neutral	0,95	deleterious	0,57	7,96	0,22	0,45	disease	0,52	neutral	0,38	neutral	0,27	neutral	0,39	2	neutral	0,47	deleterious	0,7	neutral	-6	neutral	0,26	medium_impact	0,26	medium_impact	0,2	medium_impact	-0,6	0,61	0,8	19,9	12,29	N	0,33	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12452	12452	T	C	MI.19469	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	116	39	I	T	aTt/aCt	-0,96	0	0	benign	0	neutral	0,47	neutral	3,67	neutral	3,03	neutral	1,16	neutral_impact	-0,88	neutral	0,89	neutral	0,99	neutral	-0,44	0,31	0,34	0,5	neutral	0,38	neutral	0,15	neutral	0,25	neutral	0,3	4	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,13	high_impact	2,1	medium_impact	0,2	low_impact	-2,01	0,71	0,85	19,9	12,29	N	0,36	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5936	5936	C	A	MI.1947	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	33	11	N	K	aaC/aaA	7,07	1	0	probably_damaging	1	deleterious	0	neutral	-0,97	neutral	-2,52	neutral	-1,01	high_impact	3,6	damaging	0,47	neutral	0,43	deleterious	4,3	24	0,51	0,6	disease	0,57	disease	0,84	disease	0,7	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,23	0,55	0,9	2,92	7,08	P	0,6	P	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12452	12452	T	A	MI.19470	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	116	39	I	N	aTt/aAt	-0,96	0	0	benign	0,18	neutral	0,34	neutral	3,59	neutral	-1,45	neutral	-0,8	low_impact	1,7	neutral	0,69	neutral	0,76	deleterious	2,44	19,09	0,17	0,45	disease	0,75	disease	0,61	disease	0,53	disease	0,61	2	neutral	0,6	deleterious	0,58	neutral	-6	deleterious	0,56	medium_impact	-0,12	medium_impact	0,07	medium_impact	0,35	0,62	0,8	19,9	12,29	N	0,37	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12453	12453	T	G	MI.19471	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	117	39	I	M	atT/atG	-0,27	0	0	possibly_damaging	0,52	neutral	0,24	neutral	3,64	neutral	-0,4	neutral	0,06	low_impact	1,15	neutral	0,81	neutral	0,95	neutral	1,46	13,12	0,41	0,5	disease	0,59	neutral	0,2	neutral	0,22	neutral	0,46	1	neutral	0,74	neutral	0,36	neutral	-3	deleterious	0,54	medium_impact	-0,78	medium_impact	-0,04	medium_impact	-0,15	0,82	0,85	19,9	12,29	N	0,47	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12453	12453	T	A	MI.19472	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	117	39	I	M	atT/atA	-0,27	0	0	possibly_damaging	0,52	neutral	0,24	neutral	3,64	neutral	-0,4	neutral	0,06	low_impact	1,15	neutral	0,81	neutral	0,95	deleterious	1,81	15,02	0,41	0,5	disease	0,59	neutral	0,2	neutral	0,22	neutral	0,46	1	neutral	0,74	neutral	0,36	neutral	-3	deleterious	0,54	medium_impact	-0,78	medium_impact	-0,04	medium_impact	-0,15	0,82	0,85	19,9	12,29	N	0,47	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12454	12454	G	T	MI.19473	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	118	40	V	F	Gtc/Ttc	-7,38	0	0	benign	0,14	neutral	0,71	neutral	3,57	deleterious	-4,83	deleterious	-3,35	medium_impact	2,12	neutral	0,63	neutral	0,57	neutral	1,8	14,97	0,21	0,45	neutral	0,22	disease	0,91	disease	0,66	disease	0,77	5	neutral	0,17	deleterious	0,79	neutral	-3	neutral	0,42	medium_impact	0	medium_impact	0,45	medium_impact	0,73	0,74	0,85	12,77	12,59	N	0,3	N	0,41	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12454	12454	G	C	MI.19474	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	118	40	V	L	Gtc/Ctc	-7,38	0	0	benign	0,01	neutral	0,68	neutral	3,7	neutral	-2,73	neutral	-1,56	low_impact	1,57	neutral	0,71	neutral	0,66	neutral	1,42	12,9	0,44	0,55	neutral	0,31	disease	0,71	neutral	0,48	disease	0,53	1	neutral	0,29	deleterious	0,84	neutral	-6	neutral	0,21	medium_impact	1,15	medium_impact	0,41	medium_impact	0,23	0,76	0,85	12,77	12,59	N	0,29	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12454	12454	G	A	MI.19475	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	118	40	V	I	Gtc/Atc	-7,38	0	0	benign	0	neutral	0,42	neutral	3,71	neutral	0,57	neutral	0,05	neutral_impact	-0,57	neutral	0,83	neutral	0,97	neutral	-0,56	0,16	0,46	0,55	neutral	0,25	neutral	0,25	neutral	0,31	neutral	0,4	2	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,16	low_impact	-1,72	0,87	0,9	12,77	12,59	N	0,35	N	0,02	polymorphism	1	0,01	rs200656196	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12455	12455	T	C	MI.19476	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	119	40	V	A	gTc/gCc	-1,19	0	0	benign	0,05	neutral	0,56	neutral	3,63	deleterious	-3,94	deleterious	-3,17	medium_impact	2,12	neutral	0,64	neutral	0,73	neutral	1,46	13,12	0,34	0,5	neutral	0,42	disease	0,58	disease	0,61	disease	0,65	3	neutral	0,38	deleterious	0,76	neutral	-3	neutral	0,33	medium_impact	0,47	medium_impact	0,29	medium_impact	0,73	0,8	0,85	12,77	12,59	N	0,32	N	0,34	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12455	12455	T	A	MI.19477	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	119	40	V	D	gTc/gAc	-1,19	0	0	benign	0,23	neutral	0,25	neutral	3,52	deleterious	-6,89	deleterious	-5,19	medium_impact	2,12	neutral	0,61	neutral	0,51	deleterious	2,6	20,2	0,08	0,35	disease	0,81	disease	0,9	disease	0,75	disease	0,85	7	neutral	0,7	deleterious	0,51	neutral	-3	deleterious	0,73	medium_impact	-0,25	medium_impact	-0,03	medium_impact	0,73	0,8	0,85	12,77	12,59	N	0,29	N	0,68	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12455	12455	T	G	MI.19478	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	119	40	V	G	gTc/gGc	-1,19	0	0	benign	0,15	neutral	0,36	neutral	3,54	deleterious	-6,11	deleterious	-5,88	medium_impact	2,12	neutral	0,61	neutral	0,61	deleterious	1,9	15,58	0,15	0,4	disease	0,59	disease	0,83	disease	0,68	disease	0,74	5	neutral	0,58	deleterious	0,61	neutral	-3	deleterious	0,56	medium_impact	-0,03	medium_impact	0,1	medium_impact	0,73	0,62	0,8	12,77	12,59	N	0,28	N	0,61	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12457	12457	G	T	MI.19479	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	121	41	A	S	Gca/Tca	-8,3	0	0	benign	0,29	neutral	0,58	neutral	3,74	neutral	2,74	neutral	0,95	neutral_impact	-0,36	neutral	0,82	neutral	0,98	neutral	1	10,64	0,41	0,5	neutral	0,27	neutral	0,28	neutral	0,17	neutral	0,44	1	neutral	0,32	deleterious	0,65	neutral	-6	deleterious	0,7	medium_impact	-0,38	medium_impact	0,31	low_impact	-1,53	0,8	0,85	34,33	23,28	N	0,41	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5936	5936	C	G	MI.1948	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	33	11	N	K	aaC/aaG	7,07	1	0	probably_damaging	1	deleterious	0	neutral	-0,97	neutral	-2,52	neutral	-1,01	high_impact	3,6	damaging	0,47	neutral	0,43	deleterious	3,86	23,5	0,51	0,6	disease	0,57	disease	0,84	disease	0,7	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,23	0,55	0,9	2,92	7,08	P	0,59	P	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12457	12457	G	C	MI.19480	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	121	41	A	P	Gca/Cca	-8,3	0	0	possibly_damaging	0,7	neutral	0,26	neutral	3,65	neutral	-2,6	neutral	-1,79	low_impact	1,84	neutral	0,72	neutral	0,48	deleterious	3,53	23,1	0,15	0,45	disease	0,74	disease	0,82	disease	0,59	disease	0,78	6	neutral	0,8	neutral	0,28	neutral	-3	deleterious	0,88	low_impact	-1,1	medium_impact	-0,02	medium_impact	0,48	0,79	0,85	34,33	23,28	N	0,27	N	0,71	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12457	12457	G	A	MI.19481	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	121	41	A	T	Gca/Aca	-8,3	0	0	benign	0,4	neutral	0,52	neutral	3,72	neutral	-0,95	neutral	-0,3	low_impact	1,29	neutral	0,83	neutral	0,91	deleterious	2,76	21,1	0,48	0,55	neutral	0,41	neutral	0,38	neutral	0,34	neutral	0,46	1	neutral	0,42	deleterious	0,56	neutral	-6	deleterious	0,72	medium_impact	-0,58	medium_impact	0,25	medium_impact	-0,02	0,68	0,85	34,33	23,28	N	0,32	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	COSM1155520	.	.	.	.	.	.	.	.
chrM	12458	12458	C	G	MI.19482	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	122	41	A	G	gCa/gGa	-0,04	0	0	possibly_damaging	0,48	neutral	0,41	neutral	3,68	neutral	-2,01	neutral	-1,7	low_impact	1,84	neutral	0,76	neutral	0,72	deleterious	2,63	20,4	0,27	0,45	disease	0,67	disease	0,55	neutral	0,41	disease	0,53	1	neutral	0,56	neutral	0,47	neutral	-3	deleterious	0,77	medium_impact	-0,71	medium_impact	0,15	medium_impact	0,48	0,71	0,85	34,33	23,28	N	0,3	N	0,39	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12458	12458	C	A	MI.19483	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	122	41	A	E	gCa/gAa	-0,04	0	0	possibly_damaging	0,61	neutral	0,49	neutral	3,7	neutral	-1,09	neutral	-0,85	low_impact	1,84	neutral	0,74	neutral	0,63	deleterious	3,1	22,5	0,21	0,45	disease	0,56	disease	0,77	disease	0,6	disease	0,76	5	neutral	0,59	neutral	0,44	neutral	-3	deleterious	0,82	medium_impact	-0,93	medium_impact	0,22	medium_impact	0,48	0,68	0,85	34,33	23,28	N	0,27	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12458	12458	C	T	MI.19484	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	122	41	A	V	gCa/gTa	-0,04	0	0	benign	0,07	neutral	0,58	neutral	3,73	neutral	-0,61	neutral	-1,34	low_impact	1,84	neutral	0,85	neutral	0,83	deleterious	3,16	22,6	0,36	0,5	neutral	0,4	disease	0,61	neutral	0,46	disease	0,53	1	neutral	0,35	deleterious	0,76	neutral	-6	deleterious	0,73	medium_impact	0,32	medium_impact	0,31	medium_impact	0,48	0,81	0,85	34,33	23,28	N	0,28	N	0,34	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12460	12460	T	G	MI.19485	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	124	42	S	A	Tcc/Gcc	-0,96	0	0	benign	0,02	neutral	0,57	neutral	3,83	neutral	-0,35	neutral	0,28	low_impact	1,04	neutral	0,8	neutral	0,84	deleterious	1,93	15,78	0,48	0,55	neutral	0,38	neutral	0,11	neutral	0,35	neutral	0,34	3	neutral	0,4	deleterious	0,78	neutral	-6	neutral	0,22	medium_impact	0,86	medium_impact	0,3	medium_impact	-0,25	0,75	0,85	27,36	14,7	N	0,35	N	0,19	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12460	12460	T	C	MI.19486	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	124	42	S	P	Tcc/Ccc	-0,96	0	0	benign	0,19	neutral	0,21	neutral	3,71	neutral	-2,41	neutral	-1,33	low_impact	1,74	neutral	0,64	neutral	0,45	deleterious	2,58	20	0,2	0,45	disease	0,64	disease	0,63	disease	0,65	disease	0,74	5	neutral	0,75	deleterious	0,51	neutral	-6	deleterious	0,71	medium_impact	-0,15	medium_impact	-0,09	medium_impact	0,39	0,75	0,85	27,36	14,7	N	0,32	N	0,6	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12460	12460	T	A	MI.19487	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	124	42	S	T	Tcc/Acc	-0,96	0	0	benign	0	neutral	0,45	neutral	3,83	neutral	-0,72	neutral	0,18	neutral_impact	-0,22	neutral	0,82	neutral	0,88	neutral	1,71	14,46	0,39	0,5	neutral	0,39	neutral	0,05	neutral	0,2	neutral	0,25	5	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,36	high_impact	2,1	medium_impact	0,18	low_impact	-1,4	0,77	0,85	27,36	14,7	N	0,53	P	0,22	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12461	12461	C	G	MI.19488	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	125	42	S	C	tCc/tGc	-2,57	0	0	benign	0	neutral	0,2	neutral	3,71	neutral	1,42	neutral	1,3	low_impact	0,93	neutral	0,87	neutral	0,98	deleterious	1,91	15,67	0,25	0,45	disease	0,83	neutral	0,38	neutral	0,28	disease	0,64	3	neutral	0,8	deleterious	0,6	neutral	-6	deleterious	0,68	high_impact	2,1	medium_impact	-0,1	medium_impact	-0,35	0,74	0,85	27,36	14,7	N	0,4	N	0,37	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12461	12461	C	A	MI.19489	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	125	42	S	Y	tCc/tAc	-2,57	0	0	benign	0	neutral	1	neutral	3,73	neutral	3,63	neutral	3,77	neutral_impact	-0,53	neutral	0,91	neutral	1	neutral	1,24	11,95	0,21	0,45	neutral	0,33	neutral	0,28	neutral	0,29	neutral	0,44	1	neutral	0	deleterious	1	neutral	-6	neutral	0,32	high_impact	2,1	high_impact	1,89	low_impact	-1,69	0,75	0,85	27,36	14,7	N	0,26	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5937	5937	C	T	MI.1949	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	34	12	H	Y	Cac/Tac	-1,72	0	0	probably_damaging	0,99	deleterious	0	neutral	-1,33	deleterious	-4,99	neutral	-1,06	high_impact	4,76	damaging	0,59	damaging	0,14	deleterious	3,52	23,1	0,38	0,55	disease	0,88	disease	0,87	disease	0,64	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,64	low_impact	-1,48	high_impact	3,3	0,38	0,9	2,34	6,67	P	0,69	P	0,72	disease_causing	0,98	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12461	12461	C	T	MI.19490	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	125	42	S	F	tCc/tTc	-2,57	0	0	benign	0	neutral	0,78	neutral	3,78	neutral	-0,11	neutral	2,31	low_impact	1,19	neutral	0,89	neutral	0,95	deleterious	2,16	17,24	0,25	0,45	disease	0,72	neutral	0,46	neutral	0,33	disease	0,63	3	neutral	0,22	deleterious	0,89	neutral	-6	neutral	0,21	high_impact	2,1	medium_impact	0,54	medium_impact	-0,12	0,61	0,8	27,36	14,7	N	0,27	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12463	12463	A	G	MI.19491	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	127	43	T	A	Acc/Gcc	-9,68	0	0	benign	0	neutral	0,98	neutral	3,83	neutral	5,92	neutral	2,4	neutral_impact	-0,88	neutral	0,83	neutral	0,98	neutral	-0,9	0,03	0,68	0,7	neutral	0,31	neutral	0,05	neutral	0,22	neutral	0,24	5	neutral	0	deleterious	0,99	neutral	-6	neutral	0,11	high_impact	2,1	medium_impact	1,17	low_impact	-2,01	0,44	0,8	14,93	11,68	N	0,35	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12463	12463	A	C	MI.19492	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	127	43	T	P	Acc/Ccc	-9,68	0	0	possibly_damaging	0,52	neutral	0,36	neutral	3,65	neutral	-2,01	neutral	-1,56	low_impact	1,54	damaging	0,59	neutral	0,46	deleterious	3,44	23	0,18	0,45	neutral	0,43	disease	0,82	disease	0,71	disease	0,78	6	neutral	0,63	neutral	0,42	neutral	-3	deleterious	0,69	medium_impact	-0,78	medium_impact	0,1	medium_impact	0,2	0,72	0,85	14,93	11,68	N	0,29	N	0,32	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12463	12463	A	T	MI.19493	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	127	43	T	S	Acc/Tcc	-9,68	0	0	benign	0,17	neutral	1	neutral	3,76	neutral	0,28	neutral	1,06	neutral_impact	0,32	neutral	0,83	neutral	0,97	deleterious	0,4	6,57	0,56	0,6	neutral	0,4	neutral	0,22	neutral	0,25	neutral	0,38	2	neutral	0,17	deleterious	0,92	neutral	-6	neutral	0,34	medium_impact	-0,09	high_impact	1,89	medium_impact	-0,91	0,79	0,85	14,93	11,68	N	0,29	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12464	12464	C	G	MI.19494	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	128	43	T	S	aCc/aGc	-0,27	0	0	benign	0,17	neutral	1	neutral	3,76	neutral	0,28	neutral	1,06	neutral_impact	0,32	neutral	0,83	neutral	0,97	deleterious	0,1	3,61	0,56	0,6	neutral	0,4	neutral	0,22	neutral	0,25	neutral	0,38	2	neutral	0,17	deleterious	0,92	neutral	-6	neutral	0,34	medium_impact	-0,09	high_impact	1,89	medium_impact	-0,91	0,79	0,85	14,93	11,68	N	0,27	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12464	12464	C	A	MI.19495	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	128	43	T	N	aCc/aAc	-0,27	0	0	possibly_damaging	0,6	neutral	0,61	neutral	3,65	neutral	-1,9	neutral	-1,74	low_impact	1,9	neutral	0,65	neutral	0,6	deleterious	3,14	22,6	0,53	0,6	disease	0,59	disease	0,7	disease	0,59	disease	0,69	4	neutral	0,53	deleterious	0,51	neutral	-3	deleterious	0,64	medium_impact	-0,91	medium_impact	0,34	medium_impact	0,53	0,87	0,9	14,93	11,68	N	0,24	N	0,33	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12464	12464	C	T	MI.19496	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	128	43	T	I	aCc/aTc	-0,27	0	0	benign	0,31	neutral	0,57	neutral	3,73	neutral	-2,52	neutral	-1,77	low_impact	1,9	neutral	0,71	neutral	0,66	deleterious	2,17	17,28	0,49	0,55	disease	0,74	disease	0,64	disease	0,56	disease	0,68	4	neutral	0,34	deleterious	0,63	neutral	-6	deleterious	0,59	medium_impact	-0,42	medium_impact	0,3	medium_impact	0,53	0,75	0,85	14,93	11,68	N	0,25	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12466	12466	T	G	MI.19497	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	130	44	F	V	Ttt/Gtt	-10,37	0	0	possibly_damaging	0,52	neutral	0,51	neutral	3,55	deleterious	-7,59	deleterious	-6,1	medium_impact	3,25	neutral	0,67	damaging	0,16	deleterious	3,84	23,4	0,31	0,45	neutral	0,34	disease	0,87	disease	0,7	disease	0,76	5	neutral	0,51	deleterious	0,5	NA	0	deleterious	0,76	medium_impact	-0,78	medium_impact	0,24	medium_impact	1,77	0,71	0,85	6,97	11,34	N	0,26	N	0,94	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12466	12466	T	C	MI.19498	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	130	44	F	L	Ttt/Ctt	-10,37	0	0	benign	0,03	neutral	0,65	neutral	3,59	deleterious	-5,87	deleterious	-4,96	medium_impact	2,45	neutral	0,74	neutral	0,38	deleterious	3,72	23,3	0,43	0,55	neutral	0,19	disease	0,75	disease	0,61	disease	0,52	0	neutral	0,3	deleterious	0,81	neutral	-3	deleterious	0,7	medium_impact	0,69	medium_impact	0,38	medium_impact	1,04	0,77	0,85	6,97	11,34	N	0,32	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12466	12466	T	A	MI.19499	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	130	44	F	I	Ttt/Att	-10,37	0	0	possibly_damaging	0,52	neutral	0,41	neutral	3,52	deleterious	-7,44	deleterious	-5,13	medium_impact	3,25	neutral	0,69	damaging	0,17	deleterious	4,16	23,8	0,19	0,45	neutral	0,38	disease	0,82	disease	0,7	disease	0,73	5	neutral	0,58	neutral	0,45	NA	0	deleterious	0,77	medium_impact	-0,78	medium_impact	0,15	medium_impact	1,77	0,68	0,85	6,97	11,34	N	0,28	N	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8618	8618	T	C	MI.195	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	92	31	I	T	aTc/aCc	-0,33	0	0,01	benign	0,08	neutral	0,06	neutral	4,38	neutral	-0,72	neutral	-2,08	low_impact	1,62	neutral	0,91	neutral	0,77	deleterious	0,29	5,55	0,42	0,65	neutral	0,31	neutral	0,41	neutral	0,23	neutral	0,46	1	neutral	0,93	deleterious	0,49	neutral	-6	neutral	0,18	medium_impact	0,25	medium_impact	-0,38	medium_impact	0,29	0,33	0,9	28,32	22,32	N	0,48	N	0,39	polymorphism	1	0,02	rs28358885	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5937	5937	C	A	MI.1950	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	34	12	H	N	Cac/Aac	-1,72	0	0	probably_damaging	1	deleterious	0	neutral	-1,34	deleterious	-3,82	neutral	-1,23	high_impact	4,42	neutral	0,61	damaging	0,11	deleterious	3,83	23,4	0,36	0,55	disease	0,57	disease	0,88	disease	0,65	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,98	0,34	0,9	2,34	6,67	N	0,43	N	0,86	disease_causing	0,98	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12467	12467	T	C	MI.19500	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	131	44	F	S	tTt/tCt	4,31	1	0	possibly_damaging	0,89	neutral	0,42	neutral	3,48	deleterious	-8,75	deleterious	-7,22	medium_impact	3,25	neutral	0,69	damaging	0,14	deleterious	4	23,6	0,37	0,5	disease	0,5	disease	0,85	disease	0,68	disease	0,75	5	neutral	0,89	neutral	0,27	NA	0	deleterious	0,81	low_impact	-1,61	medium_impact	0,16	medium_impact	1,77	0,69	0,85	6,97	11,34	N	0,42	N	0,99	polymorphism	0,98	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12467	12467	T	A	MI.19501	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	131	44	F	Y	tTt/tAt	4,31	1	0	possibly_damaging	0,81	neutral	1	neutral	3,46	deleterious	-5,75	deleterious	-2,75	medium_impact	3,25	neutral	0,71	damaging	0,17	deleterious	3,98	23,6	0,35	0,5	disease	0,67	disease	0,76	disease	0,7	disease	0,72	4	neutral	0,81	deleterious	0,6	NA	0	deleterious	0,8	low_impact	-1,34	high_impact	1,89	medium_impact	1,77	0,76	0,85	6,97	11,34	N	0,46	N	0,88	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12467	12467	T	G	MI.19502	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	131	44	F	C	tTt/tGt	4,31	1	0	probably_damaging	0,96	neutral	0,18	neutral	3,44	deleterious	-10,18	deleterious	-7,14	medium_impact	2,7	neutral	0,66	damaging	0,21	deleterious	3,9	23,5	0,24	0,45	disease	0,77	disease	0,83	disease	0,64	disease	0,67	3	neutral	0,98	neutral	0,11	deleterious	1	deleterious	0,82	low_impact	-2,06	medium_impact	-0,13	medium_impact	1,26	0,43	0,8	6,97	11,34	N	0,34	N	0,99	polymorphism	0,97	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12468	12468	T	G	MI.19503	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	132	44	F	L	ttT/ttG	5,69	1	0	benign	0,03	neutral	0,65	neutral	3,59	deleterious	-5,87	deleterious	-4,96	medium_impact	2,45	neutral	0,74	neutral	0,38	deleterious	4,05	23,7	0,43	0,55	neutral	0,19	disease	0,75	disease	0,61	disease	0,52	0	neutral	0,3	deleterious	0,81	neutral	-3	deleterious	0,7	medium_impact	0,69	medium_impact	0,38	medium_impact	1,04	0,77	0,85	6,97	11,34	N	0,5	N	0,91	polymorphism	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12468	12468	T	A	MI.19504	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	132	44	F	L	ttT/ttA	5,69	1	0	benign	0,03	neutral	0,65	neutral	3,59	deleterious	-5,87	deleterious	-4,96	medium_impact	2,45	neutral	0,74	neutral	0,38	deleterious	4,17	23,8	0,43	0,55	neutral	0,19	disease	0,75	disease	0,61	disease	0,52	0	neutral	0,3	deleterious	0,81	neutral	-3	deleterious	0,7	medium_impact	0,69	medium_impact	0,38	medium_impact	1,04	0,77	0,85	6,97	11,34	N	0,5	N	0,91	polymorphism	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12469	12469	A	G	MI.19505	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	133	45	I	V	Att/Gtt	-3,49	0	0,01	benign	0,01	neutral	0,95	neutral	3,79	neutral	-1,5	neutral	-0,29	low_impact	1,73	neutral	0,86	neutral	0,9	neutral	-0,18	1,19	0,64	0,7	neutral	0,49	neutral	0,21	neutral	0,3	neutral	0,36	3	neutral	0,02	deleterious	0,97	neutral	-6	neutral	0,15	medium_impact	1,15	medium_impact	0,94	medium_impact	0,38	0,68	0,85	16,75	12,35	N	0,3	N	0,39	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12469	12469	A	C	MI.19506	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	133	45	I	L	Att/Ctt	-3,49	0	0,01	benign	0,03	neutral	1	neutral	3,88	neutral	-0,83	neutral	0,19	neutral_impact	0,58	neutral	0,81	neutral	0,94	neutral	-0,08	1,87	0,36	0,5	neutral	0,33	neutral	0,15	neutral	0,22	neutral	0,28	4	neutral	0,03	deleterious	0,99	neutral	-6	neutral	0,12	medium_impact	0,69	high_impact	1,89	medium_impact	-0,67	0,79	0,85	16,75	12,35	N	0,3	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12469	12469	A	T	MI.19507	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	133	45	I	F	Att/Ttt	-3,49	0	0,01	benign	0,28	neutral	0,84	neutral	3,72	neutral	-2,81	neutral	-1,22	neutral_impact	0,33	neutral	0,81	neutral	0,94	neutral	-1,07	0,01	0,46	0,55	disease	0,67	neutral	0,16	neutral	0,19	neutral	0,36	3	neutral	0,17	deleterious	0,78	neutral	-6	neutral	0,33	medium_impact	-0,36	medium_impact	0,63	medium_impact	-0,9	0,84	0,9	16,75	12,35	N	0,32	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12470	12470	T	G	MI.19508	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	134	45	I	S	aTt/aGt	-0,5	0	0	benign	0,12	neutral	0,73	neutral	3,65	deleterious	-3,44	neutral	-2,03	medium_impact	2,08	neutral	0,82	neutral	0,66	deleterious	2,08	16,69	0,34	0,5	neutral	0,34	disease	0,59	disease	0,53	disease	0,62	2	neutral	0,16	deleterious	0,81	neutral	-3	neutral	0,24	medium_impact	0,08	medium_impact	0,47	medium_impact	0,7	0,78	0,85	16,75	12,35	N	0,24	N	0,35	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12470	12470	T	C	MI.19509	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	134	45	I	T	aTt/aCt	-0,5	0	0	benign	0	neutral	0,46	neutral	3,66	neutral	-1,61	neutral	-1,19	neutral_impact	0,14	neutral	0,9	neutral	0,98	neutral	-0,17	1,28	0,51	0,6	neutral	0,5	neutral	0,24	neutral	0,33	neutral	0,3	4	neutral	0,53	deleterious	0,73	neutral	-6	neutral	0,17	high_impact	2,1	medium_impact	0,19	low_impact	-1,08	0,78	0,85	16,75	12,35	N	0,36	N	0,06	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5937	5937	C	G	MI.1951	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	34	12	H	D	Cac/Gac	-1,72	0	0	probably_damaging	1	deleterious	0	neutral	-1,33	deleterious	-3,87	neutral	-1,58	high_impact	4,76	neutral	0,67	damaging	0,13	deleterious	3,68	23,3	0,18	0,55	disease	0,68	disease	0,87	disease	0,72	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,34	0,9	2,34	6,67	P	0,71	P	0,97	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12470	12470	T	A	MI.19510	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	134	45	I	N	aTt/aAt	-0,5	0	0	benign	0,36	neutral	0,37	neutral	3,6	deleterious	-4,64	deleterious	-3,24	medium_impact	2,08	neutral	0,69	neutral	0,53	deleterious	2,25	17,82	0,32	0,5	disease	0,75	disease	0,61	disease	0,56	disease	0,72	4	neutral	0,56	deleterious	0,51	neutral	-3	neutral	0,43	medium_impact	-0,51	medium_impact	0,11	medium_impact	0,7	0,81	0,85	16,75	12,35	N	0,29	N	0,51	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12471	12471	T	A	MI.19511	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	135	45	I	M	atT/atA	0,87	0	0	benign	0,05	neutral	0,25	neutral	3,66	neutral	-0,08	neutral	0,12	neutral_impact	0,14	neutral	0,86	neutral	0,99	deleterious	0,08	3,35	0,55	0,6	disease	0,63	neutral	0,16	neutral	0,23	neutral	0,43	1	neutral	0,73	deleterious	0,6	neutral	-6	neutral	0,16	medium_impact	0,47	medium_impact	-0,03	low_impact	-1,08	0,86	0,9	16,75	12,35	N	0,49	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12471	12471	T	G	MI.19512	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	135	45	I	M	atT/atG	0,87	0	0	benign	0,05	neutral	0,25	neutral	3,66	neutral	-0,08	neutral	0,12	neutral_impact	0,14	neutral	0,86	neutral	0,99	neutral	-0,25	0,87	0,55	0,6	disease	0,63	neutral	0,16	neutral	0,23	neutral	0,43	1	neutral	0,73	deleterious	0,6	neutral	-6	neutral	0,16	medium_impact	0,47	medium_impact	-0,03	low_impact	-1,08	0,86	0,9	16,75	12,35	N	0,47	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12472	12472	A	T	MI.19513	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	136	46	I	F	Atc/Ttc	-13,81	0	0	benign	0,01	neutral	0,86	neutral	3,63	deleterious	-4,46	neutral	-1,71	medium_impact	2,68	neutral	0,84	neutral	0,82	deleterious	3,11	22,5	0,47	0,55	neutral	0,48	disease	0,65	neutral	0,36	disease	0,52	0	neutral	0,12	deleterious	0,93	neutral	-3	deleterious	0,59	medium_impact	1,15	medium_impact	0,67	medium_impact	1,25	0,84	0,9	7,79	10,5	N	0,25	N	0,56	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12472	12472	A	C	MI.19514	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	136	46	I	L	Atc/Ctc	-13,81	0	0	benign	0	neutral	0,76	neutral	3,83	neutral	-1,77	neutral	-0,47	medium_impact	2,34	neutral	0,89	neutral	0,95	deleterious	0,36	6,23	0,39	0,5	neutral	0,28	neutral	0,41	neutral	0,3	neutral	0,46	1	neutral	0,23	deleterious	0,88	neutral	-3	neutral	0,17	high_impact	2,1	medium_impact	0,51	medium_impact	0,94	0,81	0,85	7,79	10,5	N	0,39	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12472	12472	A	G	MI.19515	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	136	46	I	V	Atc/Gtc	-13,81	0	0	benign	0	neutral	0,53	neutral	3,77	neutral	-1,39	neutral	-0,23	medium_impact	2,06	neutral	0,87	neutral	0,96	neutral	-0,89	0,03	0,64	0,7	neutral	0,28	neutral	0,12	neutral	0,29	neutral	0,26	5	neutral	0,47	deleterious	0,77	neutral	-3	neutral	0,1	high_impact	2,1	medium_impact	0,26	medium_impact	0,68	0,8	0,85	7,79	10,5	N	0,44	N	0,67	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12473	12473	T	A	MI.19516	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	137	46	I	N	aTc/aAc	-0,04	0	0	benign	0,27	neutral	0,37	neutral	3,57	deleterious	-5,9	deleterious	-3,66	medium_impact	3,02	neutral	0,7	neutral	0,44	deleterious	3,97	23,6	0,3	0,45	neutral	0,33	disease	0,71	disease	0,6	disease	0,72	4	neutral	0,55	deleterious	0,55	neutral	-3	deleterious	0,65	medium_impact	-0,34	medium_impact	0,11	medium_impact	1,56	0,8	0,85	7,79	10,5	N	0,37	N	0,86	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12473	12473	T	C	MI.19517	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	137	46	I	T	aTc/aCc	-0,04	0	0	benign	0,01	neutral	0,43	neutral	3,64	neutral	-0,52	neutral	-0,86	low_impact	1,28	neutral	0,91	neutral	0,99	neutral	-0,49	0,23	0,44	0,55	neutral	0,18	neutral	0,22	neutral	0,34	neutral	0,37	3	neutral	0,56	deleterious	0,71	neutral	-6	neutral	0,4	medium_impact	1,15	medium_impact	0,17	medium_impact	-0,03	0,8	0,85	7,79	10,5	N	0,41	N	0,34	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12473	12473	T	G	MI.19518	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	137	46	I	S	aTc/aGc	-0,04	0	0	benign	0,08	neutral	0,52	neutral	3,63	deleterious	-4,78	deleterious	-2,67	medium_impact	2,68	neutral	0,81	neutral	0,61	deleterious	2,39	18,78	0,32	0,5	neutral	0,49	disease	0,71	disease	0,58	disease	0,69	4	neutral	0,41	deleterious	0,72	neutral	-3	deleterious	0,57	medium_impact	0,26	medium_impact	0,25	medium_impact	1,25	0,77	0,85	7,79	10,5	N	0,27	N	0,67	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12474	12474	C	A	MI.19519	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	138	46	I	M	atC/atA	-1,19	0	0	possibly_damaging	0,45	neutral	0,3	neutral	3,61	deleterious	-3,93	neutral	-1,02	medium_impact	2,34	neutral	0,83	neutral	0,88	deleterious	2,15	17,16	0,46	0,55	disease	0,57	neutral	0,35	neutral	0,32	disease	0,61	2	neutral	0,66	neutral	0,43	NA	0	deleterious	0,58	medium_impact	-0,66	medium_impact	0,03	medium_impact	0,94	0,86	0,9	7,79	10,5	N	0,45	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5938	5938	A	C	MI.1952	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	35	12	H	P	cAc/cCc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	-1,34	deleterious	-4,89	neutral	-1,76	high_impact	3,8	damaging	0,59	damaging	0,13	deleterious	3,03	22,3	0,17	0,55	disease	0,85	disease	0,9	disease	0,68	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	2,41	0,29	0,9	2,34	6,67	N	0,45	N	0,9	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12474	12474	C	G	MI.19520	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	138	46	I	M	atC/atG	-1,19	0	0	possibly_damaging	0,45	neutral	0,3	neutral	3,61	deleterious	-3,93	neutral	-1,02	medium_impact	2,34	neutral	0,83	neutral	0,88	neutral	1,72	14,52	0,46	0,55	disease	0,57	neutral	0,35	neutral	0,32	disease	0,61	2	neutral	0,66	neutral	0,43	NA	0	deleterious	0,58	medium_impact	-0,66	medium_impact	0,03	medium_impact	0,94	0,86	0,9	7,79	10,5	N	0,45	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12475	12475	A	G	MI.19521	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	139	47	S	G	Agt/Ggt	-10,6	0	0	benign	0,4	neutral	0,33	neutral	3,53	deleterious	-6,69	deleterious	-3,81	medium_impact	3,25	neutral	0,67	neutral	0,54	deleterious	3,35	22,9	0,36	0,5	disease	0,78	disease	0,67	disease	0,65	disease	0,69	4	neutral	0,62	neutral	0,47	neutral	-3	deleterious	0,76	medium_impact	-0,58	medium_impact	0,06	medium_impact	1,77	0,74	0,85	21,89	7,46	N	0,33	N	0,86	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12475	12475	A	T	MI.19522	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	139	47	S	C	Agt/Tgt	-10,6	0	0	probably_damaging	0,96	neutral	0,18	neutral	3,52	deleterious	-8,45	deleterious	-4,36	medium_impact	3,25	neutral	0,7	neutral	0,47	deleterious	3,16	22,6	0,24	0,45	disease	0,83	disease	0,76	disease	0,59	disease	0,71	4	neutral	0,98	neutral	0,11	deleterious	1	deleterious	0,79	low_impact	-2,06	medium_impact	-0,13	medium_impact	1,77	0,74	0,85	21,89	7,46	N	0,31	N	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12475	12475	A	C	MI.19523	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	139	47	S	R	Agt/Cgt	-10,6	0	0	possibly_damaging	0,85	neutral	0,35	neutral	3,53	deleterious	-7,88	deleterious	-4,71	medium_impact	3,25	neutral	0,64	neutral	0,47	deleterious	3,58	23,2	0,14	0,4	disease	0,75	disease	0,86	disease	0,77	disease	0,79	6	neutral	0,87	neutral	0,25	NA	0	deleterious	0,85	low_impact	-1,46	medium_impact	0,08	medium_impact	1,77	0,81	0,85	21,89	7,46	N	0,39	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12476	12476	G	C	MI.19524	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	140	47	S	T	aGt/aCt	5,23	1	0	possibly_damaging	0,61	neutral	0,4	neutral	3,6	deleterious	-6,45	deleterious	-2,81	medium_impact	2,44	neutral	0,67	neutral	0,57	deleterious	3,21	22,7	0,36	0,5	disease	0,51	disease	0,56	disease	0,57	neutral	0,49	0	neutral	0,64	neutral	0,4	NA	0	deleterious	0,76	medium_impact	-0,93	medium_impact	0,14	medium_impact	1,03	0,84	0,9	21,89	7,46	P	0,51	P	0,7	disease_causing	0,91	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12476	12476	G	T	MI.19525	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	140	47	S	I	aGt/aTt	5,23	1	0	probably_damaging	0,92	neutral	0,4	neutral	3,58	deleterious	-6,64	deleterious	-5,62	medium_impact	2,9	neutral	0,7	neutral	0,56	deleterious	3,95	23,6	0,29	0,45	neutral	0,45	disease	0,88	disease	0,67	disease	0,76	5	neutral	0,92	neutral	0,24	deleterious	1	deleterious	0,77	low_impact	-1,75	medium_impact	0,14	medium_impact	1,45	0,84	0,9	21,89	7,46	N	0,41	N	0,99	disease_causing	0,99	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12476	12476	G	A	MI.19526	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	140	47	S	N	aGt/aAt	5,23	1	0	benign	0,05	neutral	0,32	neutral	3,54	deleterious	-7,53	deleterious	-2,83	medium_impact	2,9	neutral	0,69	neutral	0,55	deleterious	3,29	22,8	0,61	0,65	disease	0,78	disease	0,63	disease	0,61	disease	0,55	1	neutral	0,65	deleterious	0,64	neutral	-3	deleterious	0,78	medium_impact	0,47	medium_impact	0,05	medium_impact	1,45	0,66	0,8	21,89	7,46	P	0,53	P	0,83	disease_causing	0,93	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12478	12478	C	A	MI.19527	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	142	48	L	I	Ctc/Atc	-0,04	0	0	benign	0,05	neutral	0,4	neutral	3,48	deleterious	-3,06	neutral	-1,35	medium_impact	3,06	neutral	0,8	neutral	0,55	deleterious	3,79	23,4	0,44	0,55	neutral	0,38	disease	0,61	neutral	0,38	neutral	0,45	1	neutral	0,56	deleterious	0,68	neutral	-3	deleterious	0,73	medium_impact	0,47	medium_impact	0,14	medium_impact	1,59	0,76	0,85	15,09	13,17	N	0,33	N	0,51	polymorphism	0,76	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12478	12478	C	T	MI.19528	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	142	48	L	F	Ctc/Ttc	-0,04	0	0	possibly_damaging	0,72	neutral	0,71	neutral	3,4	deleterious	-4,26	deleterious	-3	medium_impact	2,17	neutral	0,65	neutral	0,31	deleterious	3,81	23,4	0,46	0,55	disease	0,66	disease	0,69	disease	0,55	disease	0,59	2	neutral	0,67	deleterious	0,5	NA	0	deleterious	0,79	low_impact	-1,14	medium_impact	0,45	medium_impact	0,78	0,72	0,85	15,09	13,17	N	0,2	N	0,69	disease_causing	0,75	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12478	12478	C	G	MI.19529	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	142	48	L	V	Ctc/Gtc	-0,04	0	0	benign	0,2	neutral	0,5	neutral	3,47	deleterious	-3,27	neutral	-1,83	medium_impact	2,71	neutral	0,69	damaging	0,28	deleterious	3,21	22,7	0,48	0,55	neutral	0,47	disease	0,6	disease	0,53	disease	0,53	1	neutral	0,4	deleterious	0,65	neutral	-3	deleterious	0,74	medium_impact	-0,17	medium_impact	0,23	medium_impact	1,27	0,71	0,85	15,09	13,17	N	0,32	N	0,46	polymorphism	0,63	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5938	5938	A	G	MI.1953	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	35	12	H	R	cAc/cGc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	-1,33	deleterious	-3,9	neutral	-1,41	high_impact	4,76	neutral	0,65	damaging	0,13	deleterious	2,81	21,4	0,33	0,55	disease	0,74	disease	0,88	disease	0,64	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,38	0,9	2,34	6,67	P	0,72	P	0,85	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12479	12479	T	C	MI.19530	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	143	48	L	P	cTc/cCc	-0,04	0	0	possibly_damaging	0,87	neutral	0,2	neutral	3,33	deleterious	-6,63	deleterious	-5,16	medium_impact	3,06	damaging	0,57	damaging	0,15	deleterious	3,69	23,3	0,13	0,4	disease	0,83	disease	0,81	disease	0,74	disease	0,79	6	neutral	0,92	neutral	0,17	NA	0	deleterious	0,87	low_impact	-1,53	medium_impact	-0,1	medium_impact	1,59	0,63	0,8	15,09	13,17	N	0,27	N	0,96	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12479	12479	T	A	MI.19531	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	143	48	L	H	cTc/cAc	-0,04	0	0	probably_damaging	0,94	neutral	0,54	neutral	3,33	deleterious	-6,83	deleterious	-5,29	medium_impact	3,06	neutral	0,63	damaging	0,22	deleterious	3,93	23,5	0,2	0,45	disease	0,83	disease	0,79	disease	0,71	disease	0,77	5	neutral	0,93	neutral	0,3	deleterious	1	deleterious	0,84	low_impact	-1,88	medium_impact	0,27	medium_impact	1,59	0,69	0,85	15,09	13,17	N	0,25	N	0,86	disease_causing	0,68	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12479	12479	T	G	MI.19532	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	143	48	L	R	cTc/cGc	-0,04	0	0	possibly_damaging	0,83	neutral	0,35	neutral	3,34	deleterious	-6,05	deleterious	-4,34	medium_impact	3,06	damaging	0,55	damaging	0,19	deleterious	3,99	23,6	0,15	0,4	disease	0,77	disease	0,89	disease	0,74	disease	0,81	6	neutral	0,85	neutral	0,26	NA	0	deleterious	0,89	low_impact	-1,4	medium_impact	0,08	medium_impact	1,59	0,72	0,85	15,09	13,17	N	0,28	N	0,97	disease_causing	0,79	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12481	12481	T	C	MI.19533	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	145	49	F	L	Ttc/Ctc	-3,26	0	0	benign	0	neutral	1	neutral	3,77	neutral	-0,18	neutral	1,78	neutral_impact	-0,36	neutral	0,85	neutral	0,93	neutral	-0,4	0,39	0,46	0,55	neutral	0,23	neutral	0,15	neutral	0,24	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,1	high_impact	1,89	low_impact	-1,53	0,74	0,85	25,21	16,14	N	0,29	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12481	12481	T	A	MI.19534	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	145	49	F	I	Ttc/Atc	-3,26	0	0	benign	0	neutral	0,67	neutral	3,74	neutral	-0,49	neutral	3,17	neutral_impact	-0,9	neutral	0,85	neutral	0,99	neutral	-0,48	0,25	0,28	0,45	neutral	0,21	neutral	0,14	neutral	0,2	neutral	0,24	5	neutral	0,33	deleterious	0,84	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	0,4	low_impact	-2,03	0,61	0,8	25,21	16,14	N	0,33	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12481	12481	T	G	MI.19535	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	145	49	F	V	Ttc/Gtc	-3,26	0	0	benign	0,01	neutral	0,54	neutral	3,68	neutral	-0,64	neutral	2,59	neutral_impact	0,45	neutral	0,85	neutral	0,99	deleterious	0,5	7,46	0,35	0,5	neutral	0,25	neutral	0,41	neutral	0,31	neutral	0,45	1	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,14	medium_impact	1,15	medium_impact	0,27	medium_impact	-0,79	0,57	0,8	25,21	16,14	N	0,29	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12482	12482	T	A	MI.19536	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	146	49	F	Y	tTc/tAc	-2,57	0	0	benign	0,19	neutral	0,72	neutral	3,6	neutral	-2,06	neutral	-0,85	low_impact	1,65	neutral	0,77	neutral	0,68	deleterious	2,35	18,47	0,37	0,5	disease	0,55	neutral	0,37	disease	0,55	disease	0,63	3	neutral	0,17	deleterious	0,77	neutral	-6	deleterious	0,5	medium_impact	-0,15	medium_impact	0,46	medium_impact	0,3	0,64	0,8	25,21	16,14	N	0,25	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12482	12482	T	C	MI.19537	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	146	49	F	S	tTc/tCc	-2,57	0	0	benign	0	neutral	0,63	neutral	3,6	neutral	-1,91	neutral	-1,82	low_impact	0,96	neutral	0,73	neutral	0,71	deleterious	2,35	18,51	0,36	0,5	neutral	0,31	neutral	0,49	disease	0,56	disease	0,61	2	neutral	0,36	deleterious	0,82	neutral	-6	deleterious	0,46	high_impact	2,1	medium_impact	0,36	medium_impact	-0,33	0,52	0,8	25,21	16,14	N	0,33	N	0,32	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12482	12482	T	G	MI.19538	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	146	49	F	C	tTc/tGc	-2,57	0	0	possibly_damaging	0,57	neutral	0,12	neutral	3,56	deleterious	-3,38	neutral	-1,01	low_impact	1,65	neutral	0,71	neutral	0,56	deleterious	3,72	23,3	0,27	0,45	disease	0,67	disease	0,66	disease	0,57	disease	0,73	5	neutral	0,88	neutral	0,28	neutral	-3	deleterious	0,66	medium_impact	-0,86	medium_impact	-0,25	medium_impact	0,3	0,4	0,8	25,21	16,14	N	0,35	N	0,45	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12483	12483	C	G	MI.19539	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	147	49	F	L	ttC/ttG	1,1	0,01	0	benign	0	neutral	1	neutral	3,77	neutral	-0,18	neutral	1,78	neutral_impact	-0,36	neutral	0,85	neutral	0,93	deleterious	-0,01	2,51	0,46	0,55	neutral	0,23	neutral	0,15	neutral	0,24	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,1	high_impact	1,89	low_impact	-1,53	0,74	0,85	25,21	16,14	N	0,3	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5938	5938	A	T	MI.1954	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	35	12	H	L	cAc/cTc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	-1,34	deleterious	-4,26	neutral	-1,94	high_impact	4,42	neutral	0,65	damaging	0,13	deleterious	3,71	23,3	0,22	0,55	disease	0,81	disease	0,92	disease	0,69	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,98	0,31	0,9	2,34	6,67	P	0,56	P	0,92	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12483	12483	C	A	MI.19540	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	147	49	F	L	ttC/ttA	1,1	0,01	0	benign	0	neutral	1	neutral	3,77	neutral	-0,18	neutral	1,78	neutral_impact	-0,36	neutral	0,85	neutral	0,93	deleterious	0,27	5,42	0,46	0,55	neutral	0,23	neutral	0,15	neutral	0,24	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,1	high_impact	1,89	low_impact	-1,53	0,74	0,85	25,21	16,14	N	0,3	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12484	12484	C	G	MI.19541	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	148	50	P	A	Ccc/Gcc	-11,28	0	0	benign	0,3	neutral	0,45	neutral	3,79	neutral	0,8	deleterious	-7,39	medium_impact	2,31	neutral	0,71	neutral	0,53	deleterious	2,85	21,6	0,35	0,5	neutral	0,46	disease	0,53	disease	0,58	neutral	0,48	0	neutral	0,46	deleterious	0,58	neutral	-3	deleterious	0,72	medium_impact	-0,4	medium_impact	0,18	medium_impact	0,91	0,8	0,85	10,95	14,85	N	0,37	N	0,51	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12484	12484	C	T	MI.19542	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	148	50	P	S	Ccc/Tcc	-11,28	0	0	benign	0,03	neutral	0,61	neutral	3,76	neutral	0,23	deleterious	-7,27	medium_impact	2	neutral	0,74	neutral	0,55	deleterious	2,62	20,3	0,44	0,55	neutral	0,22	disease	0,71	disease	0,56	disease	0,5	0	neutral	0,34	deleterious	0,79	neutral	-3	deleterious	0,72	medium_impact	0,69	medium_impact	0,34	medium_impact	0,62	0,42	0,8	10,95	14,85	N	0,34	N	0,38	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12484	12484	C	A	MI.19543	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	148	50	P	T	Ccc/Acc	-11,28	0	0	benign	0,03	neutral	0,47	neutral	3,72	neutral	-0,42	deleterious	-7,39	medium_impact	2,86	neutral	0,66	neutral	0,38	deleterious	3,47	23	0,29	0,45	neutral	0,42	disease	0,73	disease	0,58	disease	0,62	2	neutral	0,5	deleterious	0,72	neutral	-3	deleterious	0,76	medium_impact	0,69	medium_impact	0,2	medium_impact	1,41	0,77	0,85	10,95	14,85	N	0,34	N	0,7	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12485	12485	C	A	MI.19544	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	149	50	P	H	cCc/cAc	4,31	0,99	0	probably_damaging	0,94	neutral	0,46	neutral	3,66	neutral	-2,22	deleterious	-8,43	medium_impact	3,21	neutral	0,64	neutral	0,36	deleterious	3,84	23,4	0,31	0,45	disease	0,63	disease	0,83	disease	0,75	disease	0,79	6	neutral	0,93	neutral	0,26	deleterious	1	deleterious	0,8	low_impact	-1,88	medium_impact	0,19	medium_impact	1,73	0,66	0,8	10,95	14,85	N	0,47	N	0,85	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12485	12485	C	G	MI.19545	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	149	50	P	R	cCc/cGc	4,31	0,99	0	possibly_damaging	0,78	neutral	0,28	neutral	3,68	neutral	-1,21	deleterious	-8,43	medium_impact	3,21	neutral	0,65	neutral	0,37	deleterious	3,39	23	0,24	0,45	disease	0,52	disease	0,89	disease	0,78	disease	0,8	6	neutral	0,84	neutral	0,25	NA	0	deleterious	0,82	low_impact	-1,27	medium_impact	0,01	medium_impact	1,73	0,66	0,8	10,95	14,85	P	0,55	P	0,92	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12485	12485	C	T	MI.19546	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	149	50	P	L	cCc/cTc	4,31	0,99	0	benign	0,4	neutral	0,99	neutral	3,82	neutral	0,95	deleterious	-9,36	medium_impact	3,21	neutral	0,64	neutral	0,35	deleterious	4,21	23,9	0,41	0,5	disease	0,59	disease	0,82	disease	0,62	disease	0,66	3	neutral	0,39	deleterious	0,8	neutral	-3	deleterious	0,78	medium_impact	-0,58	medium_impact	1,33	medium_impact	1,73	0,8	0,85	10,95	14,85	N	0,38	N	0,89	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12487	12487	A	T	MI.19547	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	151	51	T	S	Aca/Tca	-6,01	0	0	possibly_damaging	0,57	neutral	0,57	neutral	3,74	neutral	-0,71	neutral	-1,63	medium_impact	2,37	neutral	0,85	neutral	0,76	deleterious	3,22	22,8	0,52	0,6	neutral	0,38	neutral	0,32	disease	0,51	neutral	0,47	1	neutral	0,52	deleterious	0,5	NA	0	deleterious	0,67	medium_impact	-0,86	medium_impact	0,3	medium_impact	0,96	0,84	0,9	16,58	14,93	N	0,28	N	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12487	12487	A	C	MI.19548	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	151	51	T	P	Aca/Cca	-6,01	0	0	possibly_damaging	0,88	neutral	0,3	neutral	3,67	neutral	-2,36	deleterious	-3,34	medium_impact	2,17	neutral	0,63	neutral	0,66	deleterious	3,34	22,9	0,17	0,45	disease	0,73	disease	0,74	disease	0,65	disease	0,72	4	neutral	0,9	neutral	0,21	NA	0	deleterious	0,81	low_impact	-1,57	medium_impact	0,03	medium_impact	0,78	0,69	0,85	16,58	14,93	N	0,28	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12487	12487	A	G	MI.19549	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	151	51	T	A	Aca/Gca	-6,01	0	0	benign	0,3	neutral	0,6	neutral	3,77	neutral	-0,1	neutral	-1,48	low_impact	1,68	neutral	0,85	neutral	0,93	deleterious	2,1	16,84	0,61	0,65	neutral	0,46	neutral	0,23	neutral	0,32	neutral	0,44	1	neutral	0,3	deleterious	0,65	neutral	-6	deleterious	0,66	medium_impact	-0,4	medium_impact	0,33	medium_impact	0,33	0,33	0,8	16,58	14,93	N	0,32	N	0,7	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5939	5939	C	G	MI.1955	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	36	12	H	Q	caC/caG	7,07	1	0	probably_damaging	1	deleterious	0	neutral	-1,34	deleterious	-3,97	neutral	-1,41	high_impact	4,76	neutral	0,67	damaging	0,14	deleterious	3,36	22,9	0,3	0,55	disease	0,75	disease	0,83	disease	0,7	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,42	0,9	2,34	6,67	P	0,72	P	0,83	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12488	12488	C	A	MI.19550	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	152	51	T	K	aCa/aAa	-0,27	0	0	possibly_damaging	0,69	neutral	0,34	neutral	3,68	neutral	-1,84	deleterious	-3,01	medium_impact	2,71	neutral	0,71	neutral	0,53	deleterious	4,24	23,9	0,21	0,45	neutral	0,42	disease	0,65	disease	0,67	disease	0,74	5	neutral	0,74	neutral	0,33	NA	0	deleterious	0,73	low_impact	-1,08	medium_impact	0,07	medium_impact	1,27	0,75	0,85	16,58	14,93	N	0,34	N	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12488	12488	C	T	MI.19551	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	152	51	T	M	aCa/aTa	-0,27	0	0	benign	0,06	neutral	0,37	neutral	3,72	neutral	-1,21	neutral	-1,26	low_impact	1,15	neutral	0,88	neutral	0,98	deleterious	2,46	19,19	0,4	0,5	disease	0,68	neutral	0,21	neutral	0,28	neutral	0,48	1	neutral	0,59	deleterious	0,66	neutral	-6	deleterious	0,69	medium_impact	0,39	medium_impact	0,11	medium_impact	-0,15	0,72	0,85	16,58	14,93	N	0,4	N	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12490	12490	A	G	MI.19552	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	154	52	T	A	Aca/Gca	-5,78	0	0,01	benign	0,01	neutral	0,42	neutral	3,78	neutral	-0,15	neutral	-0,7	low_impact	1,64	neutral	0,82	neutral	0,87	deleterious	0,14	4	0,62	0,65	neutral	0,3	neutral	0,18	neutral	0,42	neutral	0,36	3	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,33	medium_impact	1,15	medium_impact	0,16	medium_impact	0,3	0,61	0,8	25,37	15,62	N	0,39	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12490	12490	A	C	MI.19553	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	154	52	T	P	Aca/Cca	-5,78	0	0,01	possibly_damaging	0,63	neutral	0,26	neutral	3,69	neutral	-2,2	neutral	-2,28	medium_impact	2,33	neutral	0,67	neutral	0,42	deleterious	3,04	22,4	0,16	0,45	disease	0,73	disease	0,68	disease	0,56	disease	0,71	4	neutral	0,76	neutral	0,32	NA	0	deleterious	0,72	medium_impact	-0,97	medium_impact	-0,02	medium_impact	0,93	0,74	0,85	25,37	15,62	N	0,29	N	0,81	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12490	12490	A	T	MI.19554	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	154	52	T	S	Aca/Tca	-5,78	0	0,01	benign	0,12	neutral	0,67	neutral	3,77	neutral	-0,29	neutral	-1,08	low_impact	1,36	neutral	0,85	neutral	0,88	deleterious	0,17	4,39	0,54	0,6	neutral	0,46	neutral	0,2	neutral	0,29	neutral	0,37	3	neutral	0,22	deleterious	0,78	neutral	-6	neutral	0,39	medium_impact	0,08	medium_impact	0,4	medium_impact	0,04	0,83	0,9	25,37	15,62	N	0,33	N	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12491	12491	C	A	MI.19555	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	155	52	T	K	aCa/aAa	-1,65	0	0	benign	0,36	neutral	0,3	neutral	3,7	neutral	-1,77	neutral	-1,58	medium_impact	2,33	neutral	0,76	neutral	0,56	deleterious	2,64	20,5	0,23	0,45	disease	0,65	disease	0,58	disease	0,56	disease	0,69	4	neutral	0,64	deleterious	0,47	neutral	-3	deleterious	0,54	medium_impact	-0,51	medium_impact	0,03	medium_impact	0,93	0,79	0,85	25,37	15,62	N	0,31	N	0,73	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12491	12491	C	T	MI.19556	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	155	52	T	M	aCa/aTa	-1,65	0	0	benign	0,03	neutral	0,42	neutral	3,75	neutral	-1,11	neutral	2,13	neutral_impact	-0,18	neutral	0,89	neutral	0,99	neutral	-0,89	0,03	0,37	0,5	neutral	0,36	neutral	0,13	neutral	0,25	neutral	0,26	5	neutral	0,55	deleterious	0,7	neutral	-6	neutral	0,2	medium_impact	0,69	medium_impact	0,16	low_impact	-1,37	0,77	0,85	25,37	15,62	N	0,39	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12493	12493	A	T	MI.19557	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	157	53	M	L	Ata/Tta	-3,03	0	0	benign	0	neutral	1	neutral	4	neutral	1,35	neutral	-1,32	low_impact	0,88	neutral	0,86	neutral	0,94	neutral	-1,29	0,01	0,59	0,65	neutral	0,21	neutral	0,21	neutral	0,34	neutral	0,35	3	neutral	0	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,1	high_impact	1,89	medium_impact	-0,4	0,58	0,8	17,25	12,16	N	0,36	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12493	12493	A	C	MI.19558	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	157	53	M	L	Ata/Cta	-3,03	0	0	benign	0	neutral	1	neutral	4	neutral	1,35	neutral	-1,32	low_impact	0,88	neutral	0,86	neutral	0,94	neutral	-1,47	0	0,59	0,65	neutral	0,21	neutral	0,21	neutral	0,34	neutral	0,35	3	neutral	0	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,1	high_impact	1,89	medium_impact	-0,4	0,58	0,8	17,25	12,16	N	0,35	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12493	12493	A	G	MI.19559	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	157	53	M	V	Ata/Gta	-3,03	0	0	benign	0,05	neutral	0,52	neutral	3,86	neutral	0,45	neutral	-1,86	medium_impact	2,06	neutral	0,84	neutral	0,86	neutral	-0,53	0,18	0,54	0,6	neutral	0,45	disease	0,52	neutral	0,44	neutral	0,48	0	neutral	0,43	deleterious	0,74	neutral	-3	neutral	0,21	medium_impact	0,47	medium_impact	0,25	medium_impact	0,68	0,55	0,8	17,25	12,16	N	0,31	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5939	5939	C	A	MI.1956	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	36	12	H	Q	caC/caA	7,07	1	0	probably_damaging	1	deleterious	0	neutral	-1,34	deleterious	-3,97	neutral	-1,41	high_impact	4,76	neutral	0,67	damaging	0,14	deleterious	3,73	23,3	0,3	0,55	disease	0,75	disease	0,83	disease	0,7	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,42	0,9	2,34	6,67	P	0,72	P	0,83	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12494	12494	T	A	MI.19560	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	158	53	M	K	aTa/aAa	-2,11	0	0	benign	0,29	neutral	0,29	neutral	3,73	neutral	-0,85	deleterious	-4,12	medium_impact	2,61	neutral	0,74	neutral	0,55	deleterious	2,14	17,11	0,31	0,45	disease	0,77	disease	0,77	disease	0,71	disease	0,79	6	neutral	0,65	deleterious	0,5	neutral	-3	deleterious	0,48	medium_impact	-0,38	medium_impact	0,02	medium_impact	1,18	0,55	0,8	17,25	12,16	N	0,3	N	0,87	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12494	12494	T	C	MI.19561	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	158	53	M	T	aTa/aCa	-2,11	0	0	benign	0,15	neutral	0,49	neutral	3,78	neutral	-0,47	deleterious	-2,93	low_impact	1,17	neutral	0,85	neutral	0,94	neutral	-0,31	0,63	0,53	0,6	disease	0,6	neutral	0,45	neutral	0,44	disease	0,61	2	neutral	0,42	deleterious	0,67	neutral	-6	neutral	0,33	medium_impact	-0,03	medium_impact	0,22	medium_impact	-0,13	0,35	0,8	17,25	12,16	N	0,31	N	0,56	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12495	12495	A	T	MI.19562	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	159	53	M	I	atA/atT	0,64	0	0	benign	0,08	neutral	0,56	neutral	3,89	neutral	0,31	neutral	-1,78	low_impact	0,88	neutral	0,82	neutral	0,95	neutral	-1,37	0	0,58	0,65	neutral	0,34	neutral	0,24	neutral	0,31	neutral	0,45	1	neutral	0,36	deleterious	0,74	neutral	-6	neutral	0,16	medium_impact	0,26	medium_impact	0,29	medium_impact	-0,4	0,64	0,8	17,25	12,16	N	0,34	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12495	12495	A	C	MI.19563	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	159	53	M	I	atA/atC	0,64	0	0	benign	0,08	neutral	0,56	neutral	3,89	neutral	0,31	neutral	-1,78	low_impact	0,88	neutral	0,82	neutral	0,95	neutral	-1,44	0	0,58	0,65	neutral	0,34	neutral	0,24	neutral	0,31	neutral	0,45	1	neutral	0,36	deleterious	0,74	neutral	-6	neutral	0,16	medium_impact	0,26	medium_impact	0,29	medium_impact	-0,4	0,64	0,8	17,25	12,16	N	0,34	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12496	12496	T	A	MI.19564	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	160	54	F	I	Ttc/Atc	-3,26	0	0	possibly_damaging	0,62	neutral	0,5	neutral	3,6	neutral	-1,43	deleterious	-4,64	medium_impact	3,19	neutral	0,7	neutral	0,55	deleterious	4,19	23,8	0,28	0,45	neutral	0,48	disease	0,85	disease	0,68	disease	0,75	5	neutral	0,6	neutral	0,44	NA	0	deleterious	0,75	medium_impact	-0,95	medium_impact	0,23	medium_impact	1,71	0,51	0,8	11,44	12,6	N	0,31	N	0,94	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12496	12496	T	C	MI.19565	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	160	54	F	L	Ttc/Ctc	-3,26	0	0	benign	0,3	neutral	1	neutral	3,64	neutral	-0,77	deleterious	-4,38	medium_impact	2,64	neutral	0,77	neutral	0,85	deleterious	3,77	23,4	0,33	0,5	neutral	0,26	disease	0,68	neutral	0,48	neutral	0,49	0	neutral	0,29	deleterious	0,85	neutral	-3	deleterious	0,69	medium_impact	-0,4	high_impact	1,89	medium_impact	1,21	0,57	0,8	11,44	12,6	N	0,27	N	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12496	12496	T	G	MI.19566	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	160	54	F	V	Ttc/Gtc	-3,26	0	0	possibly_damaging	0,49	neutral	0,53	neutral	3,61	neutral	-1,13	deleterious	-5,55	medium_impact	3,19	neutral	0,71	neutral	0,5	deleterious	3,87	23,5	0,36	0,5	neutral	0,46	disease	0,87	disease	0,69	disease	0,72	4	neutral	0,47	deleterious	0,52	NA	0	deleterious	0,76	medium_impact	-0,73	medium_impact	0,26	medium_impact	1,71	0,54	0,8	11,44	12,6	N	0,29	N	0,94	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12497	12497	T	A	MI.19567	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	161	54	F	Y	tTc/tAc	2,25	0,06	0	benign	0,02	neutral	0,84	neutral	3,58	neutral	-1,7	neutral	-2,33	low_impact	1,91	neutral	0,85	neutral	0,92	deleterious	3,04	22,4	0,46	0,55	disease	0,7	disease	0,64	neutral	0,44	disease	0,52	0	neutral	0,11	deleterious	0,91	neutral	-6	deleterious	0,77	medium_impact	0,86	medium_impact	0,63	medium_impact	0,54	0,57	0,8	11,44	12,6	N	0,28	N	0,42	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12497	12497	T	C	MI.19568	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	161	54	F	S	tTc/tCc	2,25	0,06	0	possibly_damaging	0,69	neutral	0,65	neutral	3,54	neutral	-2,18	deleterious	-6,77	medium_impact	2,39	neutral	0,72	neutral	0,67	deleterious	4,12	23,8	0,36	0,5	disease	0,59	disease	0,83	disease	0,68	disease	0,69	4	neutral	0,63	deleterious	0,48	NA	0	deleterious	0,8	low_impact	-1,08	medium_impact	0,38	medium_impact	0,98	0,5	0,8	11,44	12,6	N	0,28	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12497	12497	T	G	MI.19569	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	161	54	F	C	tTc/tGc	2,25	0,06	0	probably_damaging	0,94	neutral	0,15	neutral	3,49	deleterious	-4,07	deleterious	-6,68	medium_impact	2,85	neutral	0,64	neutral	0,53	deleterious	3,9	23,5	0,26	0,45	disease	0,8	disease	0,86	disease	0,64	disease	0,75	5	neutral	0,97	neutral	0,11	deleterious	1	deleterious	0,79	low_impact	-1,88	medium_impact	-0,18	medium_impact	1,4	0,3	0,8	11,44	12,6	N	0,33	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5940	5940	A	C	MI.1957	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	37	13	K	Q	Aaa/Caa	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	-0,88	deleterious	-4,36	neutral	-0,75	high_impact	4,25	neutral	0,69	damaging	0,12	deleterious	3,07	22,4	0,38	0,55	disease	0,65	disease	0,84	disease	0,64	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,83	0,71	0,9	3,31	6,65	N	0,39	N	0,64	polymorphism	0,96	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12498	12498	C	A	MI.19570	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	162	54	F	L	ttC/ttA	0,64	0,02	0,01	benign	0,3	neutral	1	neutral	3,64	neutral	-0,77	deleterious	-4,38	medium_impact	2,64	neutral	0,77	neutral	0,85	deleterious	4,4	24,1	0,33	0,5	neutral	0,26	disease	0,68	neutral	0,48	neutral	0,49	0	neutral	0,29	deleterious	0,85	neutral	-3	deleterious	0,69	medium_impact	-0,4	high_impact	1,89	medium_impact	1,21	0,57	0,8	11,44	12,6	N	0,28	N	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12498	12498	C	G	MI.19571	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	162	54	F	L	ttC/ttG	0,64	0,02	0,01	benign	0,3	neutral	1	neutral	3,64	neutral	-0,77	deleterious	-4,38	medium_impact	2,64	neutral	0,77	neutral	0,85	deleterious	4,06	23,7	0,33	0,5	neutral	0,26	disease	0,68	neutral	0,48	neutral	0,49	0	neutral	0,29	deleterious	0,85	neutral	-3	deleterious	0,69	medium_impact	-0,4	high_impact	1,89	medium_impact	1,21	0,57	0,8	11,44	12,6	N	0,28	N	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12499	12499	A	G	MI.19572	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	163	55	M	V	Atg/Gtg	-4,86	0	0	benign	0	neutral	0,59	neutral	3,85	neutral	1,08	neutral	0,42	low_impact	1,63	neutral	0,87	neutral	0,93	neutral	-0,38	0,43	0,62	0,65	neutral	0,33	disease	0,51	disease	0,51	neutral	0,5	0	neutral	0,41	deleterious	0,8	neutral	-6	neutral	0,16	high_impact	2,1	medium_impact	0,32	medium_impact	0,29	0,52	0,8	17,25	12,35	N	0,29	N	0,28	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12499	12499	A	T	MI.19573	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	163	55	M	L	Atg/Ttg	-4,86	0	0	benign	0	neutral	1	neutral	3,97	neutral	1,79	neutral	0,89	neutral_impact	0,08	neutral	0,81	neutral	0,98	neutral	-1,43	0	0,56	0,6	neutral	0,19	neutral	0,19	neutral	0,25	neutral	0,35	3	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,1	high_impact	1,89	low_impact	-1,13	0,46	0,8	17,25	12,35	N	0,36	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12499	12499	A	C	MI.19574	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	163	55	M	L	Atg/Ctg	-4,86	0	0	benign	0	neutral	1	neutral	3,97	neutral	1,79	neutral	0,89	neutral_impact	0,08	neutral	0,81	neutral	0,98	neutral	-1,41	0	0,56	0,6	neutral	0,19	neutral	0,19	neutral	0,25	neutral	0,35	3	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,1	high_impact	1,89	low_impact	-1,13	0,46	0,8	17,25	12,35	N	0,36	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12500	12500	T	A	MI.19575	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	164	55	M	K	aTg/aAg	0,18	0	0	benign	0,07	neutral	0,35	neutral	3,76	neutral	0,02	deleterious	-3,84	medium_impact	1,98	neutral	0,76	neutral	0,62	deleterious	2,1	16,86	0,31	0,45	disease	0,7	disease	0,74	disease	0,7	disease	0,77	5	neutral	0,61	deleterious	0,64	neutral	-3	deleterious	0,49	medium_impact	0,32	medium_impact	0,08	medium_impact	0,61	0,53	0,8	17,25	12,35	N	0,28	N	0,84	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12500	12500	T	C	MI.19576	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	164	55	M	T	aTg/aCg	0,18	0	0	benign	0	neutral	0,47	neutral	3,79	neutral	0,34	neutral	-2,27	low_impact	1,28	neutral	0,86	neutral	0,9	deleterious	0,82	9,59	0,58	0,65	neutral	0,3	neutral	0,45	neutral	0,39	neutral	0,46	1	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,25	high_impact	2,1	medium_impact	0,2	medium_impact	-0,03	0,31	0,8	17,25	12,35	N	0,34	N	0,42	polymorphism	1	0,04	.	.	.	.	.	.	COSM1155521	.	.	.	.	.	.	.	.
chrM	12501	12501	G	C	MI.19577	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	165	55	M	I	atG/atC	2,25	0,04	0,07	benign	0	neutral	0,53	neutral	3,89	neutral	0,94	neutral	1,2	neutral_impact	-0,61	neutral	0,84	neutral	0,98	neutral	-0,77	0,05	0,64	0,7	neutral	0,24	neutral	0,21	neutral	0,27	neutral	0,35	3	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,26	low_impact	-1,76	0,62	0,8	17,25	12,35	N	0,34	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12501	12501	G	T	MI.19578	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	165	55	M	I	atG/atT	2,25	0,04	0,07	benign	0	neutral	0,53	neutral	3,89	neutral	0,94	neutral	1,2	neutral_impact	-0,61	neutral	0,84	neutral	0,98	neutral	-0,64	0,1	0,64	0,7	neutral	0,24	neutral	0,21	neutral	0,27	neutral	0,35	3	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,26	low_impact	-1,76	0,62	0,8	17,25	12,35	N	0,34	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12502	12502	T	C	MI.19579	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	166	56	C	R	Tgc/Cgc	-11,74	0	0	benign	0,2	neutral	0,17	neutral	3,8	neutral	0,69	neutral	0,78	low_impact	1,61	neutral	0,72	neutral	0,67	deleterious	1,82	15,07	0,33	0,5	neutral	0,27	disease	0,7	disease	0,52	disease	0,59	2	neutral	0,8	deleterious	0,49	neutral	-6	deleterious	0,74	medium_impact	-0,17	medium_impact	-0,15	medium_impact	0,27	0,33	0,8	26,53	19,85	N	0,39	N	0,44	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5940	5940	A	G	MI.1958	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	37	13	K	E	Aaa/Gaa	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	-0,88	deleterious	-4,57	neutral	-0,75	high_impact	4,45	neutral	0,63	damaging	0,14	deleterious	3,58	23,2	0,36	0,55	disease	0,64	disease	0,88	disease	0,63	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,01	0,71	0,9	3,31	6,65	N	0,45	N	0,75	polymorphism	0,94	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12502	12502	T	G	MI.19580	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	166	56	C	G	Tgc/Ggc	-11,74	0	0	benign	0,07	neutral	0,19	neutral	3,8	neutral	1,07	neutral	-0,1	low_impact	1,26	neutral	0,78	neutral	0,76	neutral	1,63	14	0,31	0,45	neutral	0,41	neutral	0,45	neutral	0,42	neutral	0,49	0	neutral	0,79	deleterious	0,56	neutral	-6	deleterious	0,7	medium_impact	0,32	medium_impact	-0,12	medium_impact	-0,05	0,4	0,8	26,53	19,85	N	0,38	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12502	12502	T	A	MI.19581	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	166	56	C	S	Tgc/Agc	-11,74	0	0	benign	0	neutral	0,38	neutral	3,87	neutral	1,79	neutral	1,23	neutral_impact	-0,09	neutral	0,88	neutral	0,98	neutral	1,63	13,99	0,46	0,55	neutral	0,31	neutral	0,25	neutral	0,24	neutral	0,43	1	neutral	0,62	deleterious	0,69	neutral	-6	deleterious	0,67	high_impact	2,1	medium_impact	0,12	low_impact	-1,29	0,5	0,8	26,53	19,85	N	0,37	N	0,39	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12503	12503	G	A	MI.19582	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	167	56	C	Y	tGc/tAc	-5,55	0	0	benign	0	neutral	0,44	neutral	3,81	neutral	1,12	neutral	3,24	neutral_impact	0,11	neutral	0,87	neutral	0,98	deleterious	0,67	8,65	0,38	0,5	neutral	0,5	neutral	0,35	neutral	0,24	neutral	0,39	2	neutral	0,56	deleterious	0,72	neutral	-6	deleterious	0,72	high_impact	2,1	medium_impact	0,18	low_impact	-1,1	0,71	0,85	26,53	19,85	N	0,3	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12503	12503	G	C	MI.19583	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	167	56	C	S	tGc/tCc	-5,55	0	0	benign	0	neutral	0,38	neutral	3,87	neutral	1,79	neutral	1,23	neutral_impact	-0,09	neutral	0,88	neutral	0,98	neutral	1,31	12,3	0,46	0,55	neutral	0,31	neutral	0,25	neutral	0,24	neutral	0,43	1	neutral	0,62	deleterious	0,69	neutral	-6	deleterious	0,67	high_impact	2,1	medium_impact	0,12	low_impact	-1,29	0,5	0,8	26,53	19,85	N	0,35	N	0,39	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12503	12503	G	T	MI.19584	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	167	56	C	F	tGc/tTc	-5,55	0	0	benign	0	neutral	0,58	neutral	3,82	neutral	1,26	neutral	1,71	neutral_impact	0,2	neutral	0,88	neutral	0,89	neutral	1,7	14,39	0,36	0,5	disease	0,54	neutral	0,5	neutral	0,23	neutral	0,45	1	neutral	0,42	deleterious	0,79	neutral	-6	deleterious	0,74	high_impact	2,1	medium_impact	0,31	low_impact	-1,02	0,59	0,8	26,53	19,85	N	0,26	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12504	12504	C	A	MI.19585	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	168	56	C	W	tgC/tgA	-0,27	0	0	possibly_damaging	0,57	neutral	0,1	neutral	3,77	neutral	-1,21	neutral	0,9	low_impact	1,61	neutral	0,81	neutral	0,62	deleterious	3,19	22,7	0,29	0,45	neutral	0,27	disease	0,64	neutral	0,29	neutral	0,47	1	neutral	0,9	neutral	0,27	neutral	-3	deleterious	0,7	medium_impact	-0,86	medium_impact	-0,29	medium_impact	0,27	0,36	0,8	26,53	19,85	N	0,37	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12504	12504	C	G	MI.19586	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	168	56	C	W	tgC/tgG	-0,27	0	0	possibly_damaging	0,57	neutral	0,1	neutral	3,77	neutral	-1,21	neutral	0,9	low_impact	1,61	neutral	0,81	neutral	0,62	deleterious	2,87	21,7	0,29	0,45	neutral	0,27	disease	0,64	neutral	0,29	neutral	0,47	1	neutral	0,9	neutral	0,27	neutral	-3	deleterious	0,7	medium_impact	-0,86	medium_impact	-0,29	medium_impact	0,27	0,36	0,8	26,53	19,85	N	0,37	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12505	12505	C	G	MI.19587	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	169	57	L	V	Cta/Gta	-2,11	0	0	benign	0,08	neutral	0,58	neutral	3,69	neutral	-0,85	neutral	-0,38	low_impact	1,79	neutral	0,81	neutral	0,71	neutral	1,31	12,33	0,49	0,55	neutral	0,23	neutral	0,33	neutral	0,35	neutral	0,45	1	neutral	0,34	deleterious	0,75	neutral	-6	neutral	0,25	medium_impact	0,26	medium_impact	0,31	medium_impact	0,43	0,56	0,8	25,37	14,1	N	0,3	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12505	12505	C	A	MI.19588	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	169	57	L	M	Cta/Ata	-2,11	0	0	benign	0,05	neutral	0,3	neutral	3,64	neutral	-1,74	neutral	0,39	low_impact	1,59	neutral	0,87	neutral	0,84	deleterious	2,21	17,59	0,31	0,45	neutral	0,37	neutral	0,24	neutral	0,22	neutral	0,46	1	neutral	0,67	deleterious	0,63	neutral	-6	deleterious	0,57	medium_impact	0,47	medium_impact	0,03	medium_impact	0,25	0,62	0,8	25,37	14,1	N	0,44	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12506	12506	T	A	MI.19589	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	170	57	L	Q	cTa/cAa	-3,26	0	0	benign	0,02	neutral	0,32	neutral	3,65	neutral	-1,89	neutral	0,38	neutral_impact	0,64	neutral	0,77	neutral	0,86	neutral	1,24	11,96	0,25	0,45	disease	0,6	neutral	0,23	neutral	0,16	disease	0,55	1	neutral	0,67	deleterious	0,65	neutral	-6	deleterious	0,61	medium_impact	0,86	medium_impact	0,05	medium_impact	-0,62	0,55	0,8	25,37	14,1	N	0,46	N	0,29	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5941	5941	A	C	MI.1959	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	38	13	K	T	aAa/aCa	6,83	1	0	probably_damaging	1	deleterious	0	neutral	-0,89	deleterious	-4,8	neutral	-1,12	high_impact	4,45	neutral	0,67	damaging	0,12	deleterious	3,5	23,1	0,24	0,55	disease	0,74	disease	0,84	disease	0,62	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,01	0,47	0,9	3,31	6,65	P	0,53	P	0,76	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12506	12506	T	C	MI.19590	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	170	57	L	P	cTa/cCa	-3,26	0	0	benign	0,41	neutral	0,21	neutral	3,59	deleterious	-3,22	neutral	-0,56	medium_impact	2,14	neutral	0,65	neutral	0,4	deleterious	3,34	22,9	0,21	0,45	disease	0,76	disease	0,79	disease	0,54	disease	0,79	6	neutral	0,76	neutral	0,4	neutral	-3	deleterious	0,72	medium_impact	-0,6	medium_impact	-0,09	medium_impact	0,75	0,35	0,8	25,37	14,1	N	0,32	N	0,58	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12506	12506	T	G	MI.19591	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	170	57	L	R	cTa/cGa	-3,26	0	0	benign	0,2	neutral	0,34	neutral	3,62	neutral	-2,18	neutral	-0,3	low_impact	1,79	neutral	0,69	neutral	0,53	deleterious	2,48	19,34	0,26	0,45	disease	0,68	disease	0,79	disease	0,52	disease	0,74	5	neutral	0,59	deleterious	0,57	neutral	-6	deleterious	0,67	medium_impact	-0,17	medium_impact	0,07	medium_impact	0,43	0,57	0,8	25,37	14,1	N	0,32	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12508	12508	G	A	MI.19592	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	172	58	D	N	Gac/Aac	-6,47	0	0	benign	0,01	neutral	0,34	neutral	3,77	neutral	-0,48	neutral	2,22	neutral_impact	0,28	neutral	0,9	neutral	0,98	deleterious	0,65	8,49	0,74	0,75	neutral	0,33	neutral	0,36	neutral	0,32	neutral	0,45	1	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,18	medium_impact	1,15	medium_impact	0,07	medium_impact	-0,95	0,49	0,8	17,74	12,53	N	0,39	N	0,02	polymorphism	1	0	.	.	.	.	.	.	COSM1169173	.	.	.	.	.	.	.	.
chrM	12508	12508	G	C	MI.19593	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	172	58	D	H	Gac/Cac	-6,47	0	0	possibly_damaging	0,63	neutral	0,52	neutral	3,68	neutral	-2,29	neutral	-0,93	low_impact	1,84	neutral	0,78	neutral	0,72	deleterious	3,13	22,6	0,39	0,5	disease	0,56	disease	0,55	disease	0,66	disease	0,72	4	neutral	0,6	neutral	0,45	neutral	-3	deleterious	0,64	medium_impact	-0,97	medium_impact	0,25	medium_impact	0,48	0,46	0,8	17,74	12,53	N	0,26	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12508	12508	G	T	MI.19594	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	172	58	D	Y	Gac/Tac	-6,47	0	0	possibly_damaging	0,78	neutral	1	neutral	3,66	neutral	-2,93	deleterious	-2,84	low_impact	1,5	neutral	0,84	neutral	0,66	deleterious	3,54	23,1	0,27	0,45	disease	0,65	disease	0,75	disease	0,66	disease	0,74	5	neutral	0,78	deleterious	0,61	neutral	-3	deleterious	0,75	low_impact	-1,27	high_impact	1,89	medium_impact	0,17	0,27	0,8	17,74	12,53	N	0,17	N	0,51	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12509	12509	A	G	MI.19595	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	173	58	D	G	gAc/gGc	-0,04	0	0	benign	0	neutral	0,35	neutral	3,77	neutral	-0,71	neutral	2,29	neutral_impact	-0,88	neutral	0,84	neutral	0,99	neutral	-0,91	0,03	0,32	0,5	neutral	0,3	neutral	0,14	neutral	0,35	neutral	0,23	5	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,08	low_impact	-2,01	0,35	0,8	17,74	12,53	N	0,39	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12509	12509	A	T	MI.19596	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	173	58	D	V	gAc/gTc	-0,04	0	0	benign	0,43	neutral	0,53	neutral	3,68	neutral	-2,36	deleterious	-3,26	low_impact	1,84	neutral	0,77	neutral	0,67	deleterious	3,22	22,7	0,29	0,45	neutral	0,48	disease	0,71	disease	0,61	disease	0,72	4	neutral	0,43	deleterious	0,55	neutral	-6	deleterious	0,64	medium_impact	-0,63	medium_impact	0,26	medium_impact	0,48	0,25	0,8	17,74	12,53	N	0,23	N	0,51	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12509	12509	A	C	MI.19597	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	173	58	D	A	gAc/gCc	-0,04	0	0	benign	0,12	neutral	0,47	neutral	3,74	neutral	-0,61	neutral	-1,34	low_impact	1,84	neutral	0,77	neutral	0,79	neutral	1,61	13,9	0,34	0,5	neutral	0,34	disease	0,56	disease	0,63	disease	0,72	4	neutral	0,45	deleterious	0,68	neutral	-6	neutral	0,31	medium_impact	0,08	medium_impact	0,2	medium_impact	0,48	0,32	0,8	17,74	12,53	N	0,31	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12510	12510	C	A	MI.19598	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	174	58	D	E	gaC/gaA	-0,27	0	0	benign	0,01	neutral	0,27	neutral	3,79	neutral	-0,26	neutral	-1	low_impact	1,5	neutral	0,83	neutral	0,78	deleterious	2,15	17,19	0,49	0,55	neutral	0,3	disease	0,54	neutral	0,45	neutral	0,46	1	neutral	0,73	deleterious	0,63	neutral	-6	neutral	0,36	medium_impact	1,15	medium_impact	-0,01	medium_impact	0,17	0,4	0,8	17,74	12,53	N	0,39	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12510	12510	C	G	MI.19599	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	174	58	D	E	gaC/gaG	-0,27	0	0	benign	0,01	neutral	0,27	neutral	3,79	neutral	-0,26	neutral	-1	low_impact	1,5	neutral	0,83	neutral	0,78	deleterious	1,85	15,27	0,49	0,55	neutral	0,3	disease	0,54	neutral	0,45	neutral	0,46	1	neutral	0,73	deleterious	0,63	neutral	-6	neutral	0,36	medium_impact	1,15	medium_impact	-0,01	medium_impact	0,17	0,4	0,8	17,74	12,53	N	0,39	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8618	8618	T	A	MI.196	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	92	31	I	N	aTc/aAc	-0,33	0	0,01	possibly_damaging	0,56	deleterious	0,02	neutral	4,29	neutral	-2,52	deleterious	-3,4	medium_impact	2,17	neutral	0,83	neutral	0,44	deleterious	3,92	23,5	0,38	0,65	disease	0,54	disease	0,69	neutral	0,26	disease	0,53	1	neutral	0,98	neutral	0,23	deleterious	4	deleterious	0,58	medium_impact	-0,86	medium_impact	-0,66	medium_impact	0,76	0,42	0,9	28,32	22,32	N	0,35	N	0,62	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5941	5941	A	T	MI.1960	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	38	13	K	M	aAa/aTa	6,83	1	0	probably_damaging	1	deleterious	0	neutral	-0,9	deleterious	-6,86	neutral	-1,12	high_impact	4,8	neutral	0,68	damaging	0,13	deleterious	3,79	23,4	0,25	0,55	disease	0,89	disease	0,85	disease	0,64	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,33	0,58	0,9	3,31	6,65	P	0,7	P	0,89	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12511	12511	C	A	MI.19600	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	175	59	Q	K	Caa/Aaa	-7,38	0	0	probably_damaging	0,99	neutral	0,29	neutral	3,78	neutral	-0,24	deleterious	-2,74	medium_impact	2,35	neutral	0,86	neutral	0,73	deleterious	2,53	19,64	0,43	0,55	disease	0,53	disease	0,59	neutral	0,36	disease	0,51	0	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,72	low_impact	-2,64	medium_impact	0,02	medium_impact	0,94	0,47	0,8	19,24	14,87	N	0,32	N	0,56	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12511	12511	C	G	MI.19601	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	175	59	Q	E	Caa/Gaa	-7,38	0	0	probably_damaging	0,98	neutral	0,27	neutral	3,78	neutral	-0,24	neutral	-2,01	medium_impact	2,35	neutral	0,86	neutral	0,52	neutral	1,56	13,65	0,4	0,5	neutral	0,38	disease	0,54	neutral	0,34	disease	0,51	0	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,67	low_impact	-2,35	medium_impact	-0,01	medium_impact	0,94	0,5	0,8	19,24	14,87	N	0,33	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12512	12512	A	G	MI.19602	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	176	59	Q	R	cAa/cGa	-1,42	0	0	probably_damaging	0,99	neutral	0,35	neutral	3,73	neutral	-0,86	deleterious	-2,74	medium_impact	2,9	neutral	0,76	neutral	0,52	deleterious	1,96	15,97	0,51	0,6	disease	0,59	disease	0,61	neutral	0,42	disease	0,51	0	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,76	low_impact	-2,64	medium_impact	0,08	medium_impact	1,45	0,28	0,8	19,24	14,87	N	0,33	N	0,42	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12512	12512	A	C	MI.19603	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	176	59	Q	P	cAa/cCa	-1,42	0	0	probably_damaging	1	neutral	0,2	neutral	3,69	neutral	-1,99	deleterious	-4,5	medium_impact	2,1	neutral	0,81	neutral	0,62	deleterious	1,99	16,13	0,16	0,45	disease	0,72	disease	0,78	neutral	0,44	disease	0,63	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,1	medium_impact	0,72	0,31	0,8	19,24	14,87	N	0,29	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12512	12512	A	T	MI.19604	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	176	59	Q	L	cAa/cTa	-1,42	0	0	probably_damaging	0,99	neutral	0,65	neutral	3,72	neutral	-1,87	deleterious	-5,3	low_impact	1,86	neutral	0,84	neutral	0,7	deleterious	1,85	15,29	0,27	0,45	neutral	0,23	disease	0,5	neutral	0,22	neutral	0,43	1	deleterious	0,99	neutral	0,33	neutral	-2	deleterious	0,65	low_impact	-2,64	medium_impact	0,38	medium_impact	0,5	0,17	0,8	19,24	14,87	N	0,26	N	0,86	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12513	12513	A	T	MI.19605	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	177	59	Q	H	caA/caT	-0,27	0	0	probably_damaging	1	neutral	0,54	neutral	3,69	neutral	-1,61	deleterious	-2,58	medium_impact	2	neutral	0,85	neutral	0,86	deleterious	1,82	15,13	0,42	0,55	disease	0,7	neutral	0,46	neutral	0,25	disease	0,63	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,27	medium_impact	0,62	0,42	0,8	19,24	14,87	N	0,26	N	0,4	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12513	12513	A	C	MI.19606	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	177	59	Q	H	caA/caC	-0,27	0	0	probably_damaging	1	neutral	0,54	neutral	3,69	neutral	-1,61	deleterious	-2,58	medium_impact	2	neutral	0,85	neutral	0,86	neutral	1,7	14,4	0,42	0,55	disease	0,7	neutral	0,46	neutral	0,25	disease	0,63	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,27	medium_impact	0,62	0,42	0,8	19,24	14,87	N	0,26	N	0,4	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12514	12514	G	A	MI.19607	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	178	60	E	K	Gaa/Aaa	-0,73	0	0	possibly_damaging	0,61	neutral	0,35	neutral	3,7	neutral	-0,9	deleterious	-3,74	medium_impact	3,21	neutral	0,61	neutral	0,45	deleterious	4,33	24	0,29	0,45	disease	0,84	disease	0,88	disease	0,75	disease	0,84	7	neutral	0,68	neutral	0,37	NA	0	deleterious	0,88	medium_impact	-0,93	medium_impact	0,08	medium_impact	1,73	0,44	0,8	5,31	10,22	N	0,35	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12514	12514	G	C	MI.19608	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	178	60	E	Q	Gaa/Caa	-0,73	0	0	possibly_damaging	0,83	neutral	0,33	neutral	3,67	neutral	-1,16	deleterious	-2,76	medium_impact	2,52	neutral	0,62	neutral	0,58	deleterious	3,21	22,7	0,46	0,55	disease	0,86	disease	0,69	neutral	0,36	disease	0,63	3	neutral	0,85	neutral	0,25	NA	0	deleterious	0,84	low_impact	-1,4	medium_impact	0,06	medium_impact	1,1	0,69	0,85	5,31	10,22	N	0,31	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12515	12515	A	G	MI.19609	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	179	60	E	G	gAa/gGa	6,84	1	0	possibly_damaging	0,61	neutral	0,38	neutral	3,63	neutral	-1,89	deleterious	-6,13	medium_impact	3,21	neutral	0,65	neutral	0,55	deleterious	3,98	23,6	0,35	0,5	disease	0,86	disease	0,8	disease	0,75	disease	0,82	6	neutral	0,66	neutral	0,39	NA	0	deleterious	0,86	medium_impact	-0,93	medium_impact	0,12	medium_impact	1,73	0,5	0,8	5,31	10,22	P	0,59	P	0,52	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5942	5942	A	C	MI.1961	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	39	13	K	N	aaA/aaC	8,69	1	0	probably_damaging	1	deleterious	0	neutral	-0,89	deleterious	-5,08	neutral	-0,94	high_impact	4,45	neutral	0,61	damaging	0,12	deleterious	3,64	23,2	0,49	0,55	disease	0,72	disease	0,87	disease	0,64	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,01	0,63	0,9	3,31	6,65	P	0,53	P	0,76	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12515	12515	A	T	MI.19610	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	179	60	E	V	gAa/gTa	6,84	1	0	possibly_damaging	0,89	neutral	0,53	neutral	3,62	neutral	-2,58	deleterious	-6,5	medium_impact	3,21	neutral	0,67	neutral	0,49	deleterious	3,85	23,4	0,27	0,45	disease	0,92	disease	0,86	disease	0,71	disease	0,81	6	neutral	0,88	neutral	0,32	NA	0	deleterious	0,87	low_impact	-1,61	medium_impact	0,26	medium_impact	1,73	0,63	0,8	5,31	10,22	P	0,56	P	0,82	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12515	12515	A	C	MI.19611	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	179	60	E	A	gAa/gCa	6,84	1	0	possibly_damaging	0,68	neutral	0,54	neutral	3,67	neutral	-1,23	deleterious	-5,51	medium_impact	3,21	neutral	0,69	neutral	0,51	deleterious	3,36	22,9	0,32	0,5	neutral	0,42	disease	0,76	disease	0,7	disease	0,68	4	neutral	0,64	neutral	0,43	NA	0	deleterious	0,77	low_impact	-1,06	medium_impact	0,27	medium_impact	1,73	0,63	0,8	5,31	10,22	P	0,52	P	0,74	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12516	12516	A	T	MI.19612	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	180	60	E	D	gaA/gaT	6,61	1	0	benign	0,02	neutral	0,25	neutral	3,66	neutral	-1,42	neutral	-1,64	medium_impact	2,02	neutral	0,78	neutral	0,89	deleterious	2,57	19,94	0,36	0,5	disease	0,75	disease	0,62	neutral	0,35	neutral	0,5	0	neutral	0,74	deleterious	0,62	neutral	-3	deleterious	0,8	medium_impact	0,86	medium_impact	-0,03	medium_impact	0,64	0,77	0,85	5,31	10,22	P	0,58	P	0,86	disease_causing	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12516	12516	A	C	MI.19613	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	180	60	E	D	gaA/gaC	6,61	1	0	benign	0,02	neutral	0,25	neutral	3,66	neutral	-1,42	neutral	-1,64	medium_impact	2,02	neutral	0,78	neutral	0,89	deleterious	2,43	19,02	0,36	0,5	disease	0,75	disease	0,62	neutral	0,35	neutral	0,5	0	neutral	0,74	deleterious	0,62	neutral	-3	deleterious	0,8	medium_impact	0,86	medium_impact	-0,03	medium_impact	0,64	0,77	0,85	5,31	10,22	P	0,57	P	0,86	disease_causing	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12517	12517	G	C	MI.19614	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	181	61	V	L	Gtt/Ctt	-0,27	0	0	benign	0,01	neutral	0,66	neutral	3,75	neutral	-0,71	neutral	-0,34	neutral_impact	0,34	neutral	0,83	neutral	0,89	deleterious	0,21	4,79	0,31	0,5	neutral	0,3	neutral	0,43	neutral	0,33	neutral	0,46	1	neutral	0,32	deleterious	0,83	neutral	-6	neutral	0,14	medium_impact	1,15	medium_impact	0,39	medium_impact	-0,89	0,73	0,85	27,36	15,3	N	0,3	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12517	12517	G	A	MI.19615	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	181	61	V	I	Gtt/Att	-0,27	0	0	benign	0	neutral	0,4	neutral	3,74	neutral	-0,66	neutral	-0,41	low_impact	1,04	neutral	0,83	neutral	0,87	deleterious	0,28	5,49	0,4	0,5	neutral	0,24	neutral	0,31	neutral	0,19	neutral	0,45	1	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,14	medium_impact	-0,25	0,77	0,85	27,36	15,3	N	0,5	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12517	12517	G	T	MI.19616	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	181	61	V	F	Gtt/Ttt	-0,27	0	0	benign	0,07	neutral	0,7	neutral	3,65	neutral	-1,75	neutral	-1,58	neutral_impact	0,49	neutral	0,8	neutral	0,74	deleterious	0,61	8,2	0,2	0,45	neutral	0,21	disease	0,7	neutral	0,39	disease	0,55	1	neutral	0,21	deleterious	0,82	neutral	-6	neutral	0,17	medium_impact	0,32	medium_impact	0,44	medium_impact	-0,76	0,56	0,8	27,36	15,3	N	0,22	N	0,21	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12518	12518	T	C	MI.19617	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	182	61	V	A	gTt/gCt	-4,86	0	0	benign	0	neutral	0,51	neutral	3,69	neutral	-1	neutral	0,24	neutral_impact	-0,55	neutral	0,86	neutral	0,98	neutral	-0,43	0,33	0,31	0,45	neutral	0,39	neutral	0,27	neutral	0,23	neutral	0,45	1	neutral	0,49	deleterious	0,76	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,24	low_impact	-1,71	0,43	0,8	27,36	15,3	N	0,32	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	COSM1155522	.	.	.	.	.	.	.	.
chrM	12518	12518	T	G	MI.19618	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	182	61	V	G	gTt/gGt	-4,86	0	0	benign	0,03	neutral	0,33	neutral	3,62	neutral	-2,52	neutral	-1,98	neutral_impact	0,24	neutral	0,8	neutral	0,74	deleterious	0,52	7,6	0,18	0,45	disease	0,67	disease	0,57	neutral	0,45	neutral	0,5	0	neutral	0,65	deleterious	0,65	neutral	-6	neutral	0,23	medium_impact	0,69	medium_impact	0,06	medium_impact	-0,98	0,55	0,8	27,36	15,3	N	0,29	N	0,17	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12518	12518	T	A	MI.19619	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	182	61	V	D	gTt/gAt	-4,86	0	0	benign	0,04	neutral	0,21	neutral	3,6	deleterious	-3,03	neutral	-2,36	low_impact	1,04	neutral	0,75	neutral	0,59	deleterious	2,47	19,29	0,12	0,4	disease	0,8	disease	0,74	disease	0,66	disease	0,78	6	neutral	0,78	deleterious	0,59	neutral	-6	neutral	0,27	medium_impact	0,57	medium_impact	-0,09	medium_impact	-0,25	0,5	0,8	27,36	15,3	N	0,29	N	0,19	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5942	5942	A	T	MI.1962	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	39	13	K	N	aaA/aaT	8,69	1	0	probably_damaging	1	deleterious	0	neutral	-0,89	deleterious	-5,08	neutral	-0,94	high_impact	4,45	neutral	0,61	damaging	0,12	deleterious	3,72	23,3	0,49	0,55	disease	0,72	disease	0,87	disease	0,64	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,01	0,63	0,9	3,31	6,65	P	0,54	P	0,76	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12520	12520	A	G	MI.19620	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	184	62	I	V	Att/Gtt	-5,78	0	0	benign	0,04	neutral	0,5	neutral	1,51	neutral	-0,89	neutral	-0,16	low_impact	1,9	neutral	0,89	neutral	0,97	neutral	1,38	12,69	0,53	0,6	neutral	0,43	neutral	0,17	neutral	0,29	neutral	0,29	4	neutral	0,46	deleterious	0,73	neutral	-6	deleterious	0,62	medium_impact	0,57	medium_impact	0,23	medium_impact	0,53	0,51	0,8	20,23	12,58	N	0,42	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12520	12520	A	T	MI.19621	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	184	62	I	F	Att/Ttt	-5,78	0	0	possibly_damaging	0,77	neutral	0,7	neutral	1,53	neutral	-0,56	deleterious	-2,63	medium_impact	2,87	neutral	0,7	neutral	0,51	deleterious	3,6	23,2	0,42	0,5	disease	0,65	disease	0,69	disease	0,51	disease	0,54	1	neutral	0,72	neutral	0,47	NA	0	deleterious	0,77	low_impact	-1,24	medium_impact	0,44	medium_impact	1,42	0,81	0,85	20,23	12,58	N	0,21	N	0,47	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12520	12520	A	C	MI.19622	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	184	62	I	L	Att/Ctt	-5,78	0	0	benign	0,17	neutral	0,65	neutral	1,53	neutral	-0,62	neutral	-0,84	medium_impact	2,12	neutral	0,82	neutral	0,94	deleterious	2,46	19,23	0,37	0,5	neutral	0,38	neutral	0,48	neutral	0,32	neutral	0,48	1	neutral	0,23	deleterious	0,74	neutral	-3	deleterious	0,65	medium_impact	-0,09	medium_impact	0,38	medium_impact	0,73	0,75	0,85	20,23	12,58	N	0,3	N	0,45	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12521	12521	T	C	MI.19623	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	185	62	I	T	aTt/aCt	-1,88	0	0	benign	0,07	neutral	0,39	neutral	1,55	neutral	-0,39	deleterious	-2,77	low_impact	0,82	neutral	0,88	neutral	0,96	neutral	1,79	14,94	0,39	0,5	disease	0,58	neutral	0,38	neutral	0,33	disease	0,62	2	neutral	0,57	deleterious	0,66	neutral	-6	deleterious	0,72	medium_impact	0,32	medium_impact	0,13	medium_impact	-0,45	0,63	0,8	20,23	12,58	N	0,32	N	0,14	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12521	12521	T	G	MI.19624	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	185	62	I	S	aTt/aGt	-1,88	0	0	possibly_damaging	0,57	neutral	0,41	neutral	1,52	neutral	-0,69	deleterious	-3,9	medium_impact	2,17	neutral	0,79	neutral	0,72	deleterious	4,04	23,7	0,27	0,45	neutral	0,48	disease	0,7	neutral	0,42	disease	0,53	1	neutral	0,62	neutral	0,42	NA	0	deleterious	0,75	medium_impact	-0,86	medium_impact	0,15	medium_impact	0,78	0,52	0,8	20,23	12,58	N	0,27	N	0,56	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12521	12521	T	A	MI.19625	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	185	62	I	N	aTt/aAt	-1,88	0	0	possibly_damaging	0,77	neutral	0,31	neutral	1,47	neutral	-1,5	deleterious	-4,86	medium_impact	2,87	neutral	0,66	neutral	0,44	deleterious	4,15	23,8	0,25	0,45	neutral	0,25	disease	0,78	disease	0,63	disease	0,74	5	neutral	0,81	neutral	0,27	NA	0	deleterious	0,7	low_impact	-1,24	medium_impact	0,04	medium_impact	1,42	0,54	0,8	20,23	12,58	N	0,33	N	0,79	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12522	12522	T	G	MI.19626	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	186	62	I	M	atT/atG	0,41	0	0	benign	0,12	neutral	0,22	neutral	1,48	neutral	-1,37	neutral	-0,68	low_impact	1,25	neutral	0,84	neutral	0,96	deleterious	1,9	15,6	0,48	0,55	neutral	0,26	neutral	0,37	neutral	0,3	neutral	0,46	1	neutral	0,75	deleterious	0,55	neutral	-6	deleterious	0,65	medium_impact	0,08	medium_impact	-0,07	medium_impact	-0,06	0,8	0,85	20,23	12,58	N	0,44	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12522	12522	T	A	MI.19627	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	186	62	I	M	atT/atA	0,41	0	0	benign	0,12	neutral	0,22	neutral	1,48	neutral	-1,37	neutral	-0,68	low_impact	1,25	neutral	0,84	neutral	0,96	deleterious	2,22	17,67	0,48	0,55	neutral	0,26	neutral	0,37	neutral	0,3	neutral	0,46	1	neutral	0,75	deleterious	0,55	neutral	-6	deleterious	0,65	medium_impact	0,08	medium_impact	-0,07	medium_impact	-0,06	0,8	0,85	20,23	12,58	N	0,45	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12523	12523	A	C	MI.19628	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	187	63	I	L	Atc/Ctc	-6,7	0	0	benign	0,22	neutral	0,75	neutral	1,22	neutral	-1,77	neutral	-1,72	low_impact	1,83	neutral	0,82	neutral	0,9	deleterious	0,77	9,27	0,39	0,5	neutral	0,32	neutral	0,36	neutral	0,3	neutral	0,46	1	neutral	0,16	deleterious	0,77	neutral	-6	neutral	0,23	medium_impact	-0,22	medium_impact	0,5	medium_impact	0,47	0,68	0,85	3,32	8,29	N	0,3	N	0,63	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12523	12523	A	T	MI.19629	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	187	63	I	F	Atc/Ttc	-6,7	0	0	possibly_damaging	0,83	neutral	0,85	neutral	1,15	neutral	-2,54	deleterious	-3,66	medium_impact	2,58	neutral	0,79	neutral	0,36	deleterious	3,47	23	0,39	0,5	disease	0,66	disease	0,61	disease	0,64	disease	0,56	1	neutral	0,81	deleterious	0,51	NA	0	deleterious	0,7	low_impact	-1,4	medium_impact	0,65	medium_impact	1,15	0,64	0,8	3,32	8,29	N	0,17	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5943	5943	G	C	MI.1963	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	40	14	D	H	Gac/Cac	2,67	1	0	probably_damaging	1	deleterious	0,03	neutral	-1,24	neutral	-1,99	neutral	-1,34	high_impact	3,99	damaging	0,59	damaging	0,06	deleterious	3,43	23	0,33	0,55	neutral	0,48	disease	0,9	disease	0,61	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,83	low_impact	-3,58	medium_impact	-0,65	high_impact	2,59	0,63	0,9	1,56	6,7	N	0,37	N	0,97	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12523	12523	A	G	MI.19630	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	187	63	I	V	Atc/Gtc	-6,7	0	0	benign	0,04	neutral	0,6	neutral	1,18	neutral	-2,17	neutral	-0,6	low_impact	1,25	neutral	0,87	neutral	0,93	neutral	-0,43	0,32	0,54	0,6	neutral	0,26	neutral	0,12	neutral	0,31	neutral	0,3	4	neutral	0,35	deleterious	0,78	neutral	-6	neutral	0,1	medium_impact	0,57	medium_impact	0,33	medium_impact	-0,06	0,57	0,8	3,32	8,29	N	0,38	N	0,05	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12524	12524	T	C	MI.19631	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	188	63	I	T	aTc/aCc	-0,27	0	0	benign	0,1	neutral	0,44	neutral	1,13	neutral	-2,8	deleterious	-3,94	low_impact	1,2	neutral	0,85	neutral	0,92	neutral	1,39	12,73	0,32	0,5	neutral	0,45	neutral	0,24	neutral	0,31	neutral	0,45	1	neutral	0,5	deleterious	0,67	neutral	-6	deleterious	0,53	medium_impact	0,16	medium_impact	0,18	medium_impact	-0,11	0,63	0,8	3,32	8,29	N	0,4	N	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12524	12524	T	A	MI.19632	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	188	63	I	N	aTc/aAc	-0,27	0	0	probably_damaging	0,9	neutral	0,35	neutral	1,06	deleterious	-4,97	deleterious	-6,18	medium_impact	2,45	neutral	0,74	neutral	0,52	deleterious	4,19	23,9	0,25	0,45	disease	0,85	disease	0,73	disease	0,66	disease	0,76	5	neutral	0,91	neutral	0,23	deleterious	1	deleterious	0,79	low_impact	-1,65	medium_impact	0,08	medium_impact	1,04	0,45	0,8	3,32	8,29	N	0,27	N	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12524	12524	T	G	MI.19633	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	188	63	I	S	aTc/aGc	-0,27	0	0	possibly_damaging	0,56	neutral	0,51	neutral	1,08	deleterious	-3,81	deleterious	-5,19	low_impact	1,75	neutral	0,75	neutral	0,73	deleterious	2,8	21,4	0,26	0,45	disease	0,73	disease	0,63	neutral	0,42	disease	0,54	1	neutral	0,54	deleterious	0,48	neutral	-3	deleterious	0,71	medium_impact	-0,85	medium_impact	0,24	medium_impact	0,4	0,52	0,8	3,32	8,29	N	0,29	N	0,92	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12525	12525	C	G	MI.19634	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	189	63	I	M	atC/atG	1,1	0	0	benign	0,16	neutral	0,28	neutral	1,08	deleterious	-3,91	neutral	-2,44	medium_impact	1,94	neutral	0,84	neutral	0,79	deleterious	2,03	16,39	0,4	0,5	neutral	0,37	neutral	0,3	neutral	0,3	neutral	0,47	1	neutral	0,67	deleterious	0,56	neutral	-3	deleterious	0,62	medium_impact	-0,06	medium_impact	0,01	medium_impact	0,57	0,7	0,85	3,32	8,29	N	0,45	N	0,63	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12525	12525	C	A	MI.19635	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	189	63	I	M	atC/atA	1,1	0	0	benign	0,16	neutral	0,28	neutral	1,08	deleterious	-3,91	neutral	-2,44	medium_impact	1,94	neutral	0,84	neutral	0,79	deleterious	2,42	18,98	0,4	0,5	neutral	0,37	neutral	0,3	neutral	0,3	neutral	0,47	1	neutral	0,67	deleterious	0,56	neutral	-3	deleterious	0,62	medium_impact	-0,06	medium_impact	0,01	medium_impact	0,57	0,7	0,85	3,32	8,29	N	0,45	N	0,63	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12526	12526	T	G	MI.19636	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	190	64	S	A	Tcg/Gcg	-9,22	0	0	possibly_damaging	0,44	neutral	0,61	neutral	1,53	neutral	-0,8	neutral	-2,49	low_impact	1,4	neutral	0,79	neutral	0,65	deleterious	1,87	15,41	0,42	0,5	neutral	0,47	neutral	0,37	disease	0,59	neutral	0,49	0	neutral	0,38	deleterious	0,59	neutral	-3	neutral	0,35	medium_impact	-0,65	medium_impact	0,34	medium_impact	0,08	0,73	0,85	25,54	16,09	N	0,26	N	0,28	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12526	12526	T	C	MI.19637	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	190	64	S	P	Tcg/Ccg	-9,22	0	0	probably_damaging	0,9	neutral	0,23	neutral	1,56	neutral	-0,35	deleterious	-4,34	medium_impact	3,1	damaging	0,5	neutral	0,37	deleterious	3,71	23,3	0,18	0,45	disease	0,74	disease	0,82	disease	0,57	disease	0,77	5	neutral	0,93	neutral	0,17	deleterious	1	deleterious	0,79	low_impact	-1,65	medium_impact	-0,06	medium_impact	1,63	0,63	0,8	25,54	16,09	N	0,35	N	0,69	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12526	12526	T	A	MI.19638	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	190	64	S	T	Tcg/Acg	-9,22	0	0	benign	0,06	neutral	0,75	neutral	1,64	neutral	0,57	neutral	-1,96	neutral_impact	-0,44	neutral	0,8	neutral	0,93	neutral	-1,04	0,01	0,37	0,5	neutral	0,33	neutral	0,07	neutral	0,18	neutral	0,25	5	neutral	0,16	deleterious	0,85	neutral	-6	neutral	0,14	medium_impact	0,39	medium_impact	0,5	low_impact	-1,61	0,81	0,85	25,54	16,09	N	0,44	N	0,02	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12527	12527	C	T	MI.19639	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	191	64	S	L	tCg/tTg	-0,04	0	0	possibly_damaging	0,56	neutral	1	neutral	1,54	neutral	-0,64	deleterious	-4,86	low_impact	1,44	neutral	0,82	neutral	0,63	deleterious	2,89	21,8	0,3	0,45	neutral	0,2	disease	0,6	neutral	0,37	neutral	0,45	1	neutral	0,56	deleterious	0,72	neutral	-3	deleterious	0,46	medium_impact	-0,85	high_impact	1,89	medium_impact	0,11	0,87	0,9	25,54	16,09	N	0,22	N	0,66	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5943	5943	G	A	MI.1964	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	40	14	D	N	Gac/Aac	2,67	1	0	probably_damaging	1	neutral	0,05	neutral	-1,21	neutral	-1,33	neutral	-0,91	medium_impact	2,8	damaging	0,52	damaging	0,08	deleterious	4,07	23,7	0,67	0,7	neutral	0,3	disease	0,85	disease	0,51	disease	0,55	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,78	low_impact	-3,58	medium_impact	-0,52	medium_impact	1,49	0,82	0,9	1,56	6,7	N	0,5	N	0,89	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12527	12527	C	G	MI.19640	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	191	64	S	W	tCg/tGg	-0,04	0	0	benign	0,04	neutral	0,37	neutral	1,46	deleterious	-4,54	deleterious	-5,76	medium_impact	2,42	neutral	0,76	neutral	0,48	deleterious	4,15	23,8	0,19	0,45	disease	0,89	disease	0,82	disease	0,59	disease	0,8	6	neutral	0,6	deleterious	0,67	neutral	-3	deleterious	0,83	medium_impact	0,57	medium_impact	0,11	medium_impact	1,01	0,51	0,8	25,54	16,09	N	0,26	N	0,21	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12529	12529	A	T	MI.19641	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	193	65	N	Y	Aac/Tac	-9,91	0	0	probably_damaging	0,95	neutral	1	neutral	1,5	neutral	-1,92	deleterious	-7,56	medium_impact	2,98	neutral	0,82	neutral	0,58	deleterious	3,53	23,1	0,44	0,55	disease	0,69	disease	0,55	neutral	0,49	disease	0,51	0	neutral	0,95	deleterious	0,53	deleterious	1	deleterious	0,76	low_impact	-1,96	high_impact	1,89	medium_impact	1,52	0,36	0,8	13,76	11,33	N	0,22	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12529	12529	A	C	MI.19642	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	193	65	N	H	Aac/Cac	-9,91	0	0	probably_damaging	0,93	neutral	0,54	neutral	1,51	neutral	-1,61	deleterious	-4,69	medium_impact	2,54	neutral	0,76	neutral	0,57	deleterious	2,87	21,7	0,58	0,65	disease	0,52	neutral	0,38	disease	0,55	neutral	0,5	0	neutral	0,92	neutral	0,31	deleterious	1	deleterious	0,69	low_impact	-1,81	medium_impact	0,27	medium_impact	1,12	0,55	0,8	13,76	11,33	N	0,28	N	0,48	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12529	12529	A	G	MI.19643	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	193	65	N	D	Aac/Gac	-9,91	0	0	possibly_damaging	0,56	neutral	0,21	neutral	1,49	neutral	-2,66	deleterious	-4,74	medium_impact	2,63	neutral	0,74	neutral	0,48	deleterious	2,1	16,86	0,67	0,7	disease	0,6	neutral	0,39	disease	0,74	disease	0,68	4	neutral	0,78	neutral	0,33	NA	0	deleterious	0,52	medium_impact	-0,85	medium_impact	-0,09	medium_impact	1,2	0,54	0,8	13,76	11,33	N	0,37	N	0,63	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12530	12530	A	T	MI.19644	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	194	65	N	I	aAc/aTc	1,56	0	0	possibly_damaging	0,78	neutral	0,41	neutral	1,61	neutral	0,28	deleterious	-8,52	medium_impact	2,75	neutral	0,8	neutral	0,58	deleterious	3,7	23,3	0,4	0,5	disease	0,52	disease	0,6	disease	0,64	disease	0,65	3	neutral	0,78	neutral	0,32	NA	0	deleterious	0,7	low_impact	-1,27	medium_impact	0,15	medium_impact	1,31	0,3	0,8	13,76	11,33	N	0,33	N	0,87	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12530	12530	A	C	MI.19645	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	194	65	N	T	aAc/aCc	1,56	0	0	benign	0,06	neutral	0,42	neutral	1,57	neutral	-0,18	deleterious	-5,48	low_impact	1,85	neutral	0,84	neutral	0,78	deleterious	0,56	7,9	0,51	0,6	neutral	0,44	neutral	0,3	neutral	0,38	neutral	0,46	1	neutral	0,53	deleterious	0,68	neutral	-6	neutral	0,42	medium_impact	0,39	medium_impact	0,16	medium_impact	0,49	0,44	0,8	13,76	11,33	N	0,4	N	0,22	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12530	12530	A	G	MI.19646	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	194	65	N	S	aAc/aGc	1,56	0	0	benign	0,06	neutral	0,44	neutral	1,53	neutral	-1,13	deleterious	-4,66	low_impact	1,51	neutral	0,82	neutral	0,56	neutral	-0,09	1,78	0,62	0,65	neutral	0,39	neutral	0,18	neutral	0,41	neutral	0,3	4	neutral	0,51	deleterious	0,69	neutral	-6	neutral	0,18	medium_impact	0,39	medium_impact	0,18	medium_impact	0,18	0,28	0,8	13,76	11,33	N	0,42	N	0,06	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12531	12531	C	A	MI.19647	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	195	65	N	K	aaC/aaA	-0,04	0	0	possibly_damaging	0,56	neutral	0,3	neutral	1,51	neutral	-1,63	deleterious	-5,68	medium_impact	2,89	neutral	0,73	neutral	0,41	deleterious	2,6	20,2	0,67	0,7	neutral	0,47	neutral	0,48	disease	0,73	disease	0,61	2	neutral	0,7	neutral	0,37	NA	0	deleterious	0,55	medium_impact	-0,85	medium_impact	0,03	medium_impact	1,44	0,54	0,8	13,76	11,33	N	0,36	N	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12531	12531	C	G	MI.19648	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	195	65	N	K	aaC/aaG	-0,04	0	0	possibly_damaging	0,56	neutral	0,3	neutral	1,51	neutral	-1,63	deleterious	-5,68	medium_impact	2,89	neutral	0,73	neutral	0,41	deleterious	2,24	17,77	0,67	0,7	neutral	0,47	neutral	0,48	disease	0,73	disease	0,61	2	neutral	0,7	neutral	0,37	NA	0	deleterious	0,55	medium_impact	-0,85	medium_impact	0,03	medium_impact	1,44	0,54	0,8	13,76	11,33	N	0,36	N	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12532	12532	T	C	MI.19649	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	196	66	W	R	Tga/Cga	-0,04	0	0	probably_damaging	0,98	neutral	0,35	neutral	1,35	deleterious	-3,43	deleterious	-13,78	medium_impact	3,5	neutral	0,66	neutral	0,36	deleterious	3,43	23	0,34	0,5	disease	0,7	disease	0,8	disease	0,81	disease	0,8	6	neutral	0,98	neutral	0,19	deleterious	1	deleterious	0,84	low_impact	-2,35	medium_impact	0,08	medium_impact	1,99	0,26	0,8	21,89	6,97	N	0,45	N	0,97	polymorphism	0,93	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5943	5943	G	T	MI.1965	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	40	14	D	Y	Gac/Tac	2,67	1	0	probably_damaging	1	deleterious	0	neutral	-1,24	deleterious	-3,06	neutral	-1,75	high_impact	3,85	damaging	0,56	damaging	0,06	deleterious	3,73	23,3	0,25	0,55	disease	0,61	disease	0,95	disease	0,61	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,46	0,35	0,9	1,56	6,7	N	0,37	N	0,94	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12532	12532	T	G	MI.19650	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	196	66	W	G	Tga/Gga	-0,04	0	0	probably_damaging	0,97	neutral	0,33	neutral	1,4	neutral	-1,95	deleterious	-12,8	medium_impact	2,81	neutral	0,66	neutral	0,51	deleterious	3,75	23,3	0,3	0,45	disease	0,71	disease	0,73	disease	0,78	disease	0,76	5	neutral	0,97	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-2,18	medium_impact	0,06	medium_impact	1,36	0,24	0,8	21,89	6,97	N	0,41	N	0,97	polymorphism	0,82	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12533	12533	G	T	MI.19651	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	197	66	W	L	tGa/tTa	4,31	1	0	benign	0,17	neutral	0,65	neutral	1,57	neutral	-0,08	deleterious	-12,8	low_impact	1,67	neutral	0,7	neutral	0,62	deleterious	4,02	23,6	0,29	0,45	neutral	0,35	disease	0,58	disease	0,61	neutral	0,46	1	neutral	0,23	deleterious	0,74	neutral	-6	deleterious	0,73	medium_impact	-0,09	medium_impact	0,38	medium_impact	0,32	0,3	0,8	21,89	6,97	N	0,4	N	0,97	polymorphism	0,63	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12533	12533	G	C	MI.19652	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	197	66	W	S	tGa/tCa	4,31	1	0	probably_damaging	0,98	neutral	0,41	neutral	1,45	neutral	-1,16	deleterious	-13,78	medium_impact	2,69	neutral	0,72	neutral	0,62	deleterious	3,81	23,4	0,27	0,45	neutral	0,4	disease	0,77	disease	0,75	disease	0,64	3	neutral	0,98	neutral	0,22	deleterious	1	deleterious	0,8	low_impact	-2,35	medium_impact	0,15	medium_impact	1,25	0,18	0,8	21,89	6,97	N	0,42	N	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12534	12534	A	C	MI.19653	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	198	66	W	C	tgA/tgC	2,94	0,99	0	probably_damaging	0,99	neutral	0,18	neutral	1,35	deleterious	-3,95	deleterious	-12,8	medium_impact	3,5	neutral	0,64	neutral	0,4	deleterious	3,84	23,4	0,26	0,45	disease	0,75	disease	0,82	disease	0,74	disease	0,77	5	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,82	low_impact	-2,64	medium_impact	-0,13	medium_impact	1,99	0,26	0,8	21,89	6,97	N	0,42	N	0,98	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12534	12534	A	T	MI.19654	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	198	66	W	C	tgA/tgT	2,94	0,99	0	probably_damaging	0,99	neutral	0,18	neutral	1,35	deleterious	-3,95	deleterious	-12,8	medium_impact	3,5	neutral	0,64	neutral	0,4	deleterious	3,92	23,5	0,26	0,45	disease	0,75	disease	0,82	disease	0,74	disease	0,77	5	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,82	low_impact	-2,64	medium_impact	-0,13	medium_impact	1,99	0,26	0,8	21,89	6,97	N	0,43	N	0,98	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12535	12535	C	T	MI.19655	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	199	67	H	Y	Cac/Tac	0,41	0,04	0	probably_damaging	0,95	neutral	1	neutral	1,49	neutral	-2,74	deleterious	-5,47	medium_impact	2,08	neutral	0,82	neutral	0,52	deleterious	3,36	22,9	0,63	0,7	disease	0,65	neutral	0,47	neutral	0,44	disease	0,63	3	neutral	0,95	deleterious	0,53	deleterious	1	deleterious	0,72	low_impact	-1,96	high_impact	1,89	medium_impact	0,7	0,43	0,8	15,59	14,68	N	0,21	N	0,77	polymorphism	1	0,05	rs876661356	Uncertain significance	not_specified	RCV000223843.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	12535	12535	C	A	MI.19656	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	199	67	H	N	Cac/Aac	0,41	0,04	0	probably_damaging	0,95	neutral	0,31	neutral	1,65	neutral	0,71	deleterious	-5,28	low_impact	1,54	neutral	0,83	neutral	0,81	deleterious	2,27	17,99	0,63	0,7	disease	0,58	neutral	0,29	neutral	0,4	disease	0,58	2	neutral	0,96	neutral	0,18	neutral	-2	deleterious	0,66	low_impact	-1,96	medium_impact	0,04	medium_impact	0,2	0,67	0,85	15,59	14,68	N	0,38	N	0,61	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12535	12535	C	G	MI.19657	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	199	67	H	D	Cac/Gac	0,41	0,04	0	probably_damaging	0,95	neutral	0,2	neutral	1,62	neutral	0,45	deleterious	-7,62	medium_impact	1,96	neutral	0,75	neutral	0,41	deleterious	3,46	23	0,29	0,45	disease	0,7	neutral	0,47	disease	0,63	disease	0,66	3	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,71	low_impact	-1,96	medium_impact	-0,1	medium_impact	0,59	0,55	0,8	15,59	14,68	N	0,37	N	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12536	12536	A	G	MI.19658	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	200	67	H	R	cAc/cGc	-0,04	0	0	probably_damaging	0,97	neutral	0,35	neutral	1,6	neutral	0,23	deleterious	-6,9	medium_impact	2,93	neutral	0,81	neutral	0,6	deleterious	2,44	19,09	0,61	0,65	disease	0,62	neutral	0,38	disease	0,56	disease	0,63	3	neutral	0,97	neutral	0,19	deleterious	1	deleterious	0,7	low_impact	-2,18	medium_impact	0,08	medium_impact	1,47	0,43	0,8	15,59	14,68	N	0,35	N	0,85	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12536	12536	A	T	MI.19659	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	200	67	H	L	cAc/cTc	-0,04	0	0	possibly_damaging	0,83	neutral	0,65	neutral	1,54	neutral	-0,7	deleterious	-9,84	medium_impact	2,73	neutral	0,82	neutral	0,48	neutral	1,76	14,77	0,31	0,45	neutral	0,2	disease	0,52	disease	0,58	disease	0,69	4	neutral	0,8	neutral	0,41	NA	0	neutral	0,38	low_impact	-1,4	medium_impact	0,38	medium_impact	1,29	0,34	0,8	15,59	14,68	N	0,29	N	0,95	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5944	5944	A	C	MI.1966	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	41	14	D	A	gAc/gCc	9,38	1	0	probably_damaging	1	deleterious	0	neutral	-1,22	neutral	-0,99	neutral	-1,56	high_impact	4,2	neutral	0,65	damaging	0,06	deleterious	3,45	23	0,3	0,55	neutral	0,28	disease	0,88	disease	0,62	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,78	0,57	0,9	1,56	6,7	N	0,49	N	0,85	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12536	12536	A	C	MI.19660	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	200	67	H	P	cAc/cCc	-0,04	0	0	probably_damaging	0,98	neutral	0,2	neutral	1,54	neutral	-0,88	deleterious	-8,86	low_impact	1,05	neutral	0,72	neutral	0,6	deleterious	2,85	21,6	0,27	0,45	disease	0,74	disease	0,71	disease	0,59	disease	0,6	2	deleterious	0,99	neutral	0,11	neutral	-2	deleterious	0,82	low_impact	-2,35	medium_impact	-0,1	medium_impact	-0,24	0,41	0,8	15,59	14,68	N	0,33	N	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12537	12537	C	A	MI.19661	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	201	67	H	Q	caC/caA	0,18	0	0	probably_damaging	0,98	neutral	0,29	neutral	1,56	neutral	-0,37	deleterious	-6,88	low_impact	1,46	neutral	0,84	neutral	0,75	deleterious	2,03	16,41	0,6	0,65	disease	0,62	neutral	0,23	neutral	0,37	disease	0,57	1	deleterious	0,98	neutral	0,16	neutral	-2	deleterious	0,7	low_impact	-2,35	medium_impact	0,02	medium_impact	0,13	0,57	0,8	15,59	14,68	N	0,41	N	0,77	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12537	12537	C	G	MI.19662	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	201	67	H	Q	caC/caG	0,18	0	0	probably_damaging	0,98	neutral	0,29	neutral	1,56	neutral	-0,37	deleterious	-6,88	low_impact	1,46	neutral	0,84	neutral	0,75	neutral	1,77	14,83	0,6	0,65	disease	0,62	neutral	0,23	neutral	0,37	disease	0,57	1	deleterious	0,98	neutral	0,16	neutral	-2	deleterious	0,7	low_impact	-2,35	medium_impact	0,02	medium_impact	0,13	0,57	0,8	15,59	14,68	N	0,4	N	0,77	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12538	12538	T	G	MI.19663	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	202	68	W	G	Tga/Gga	-3,94	0	0	probably_damaging	1	neutral	0,32	neutral	0,44	deleterious	-7,81	deleterious	-12,8	high_impact	4,21	damaging	0,55	damaging	0,06	deleterious	3,72	23,3	0,24	0,45	disease	0,88	disease	0,76	disease	0,81	disease	0,83	7	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,05	high_impact	2,64	0,31	0,8	25,54	7,33	N	0,37	N	0,97	polymorphism	0,96	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12538	12538	T	C	MI.19664	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	202	68	W	R	Tga/Cga	-3,94	0	0	probably_damaging	1	neutral	0,34	neutral	0,44	deleterious	-7,43	deleterious	-13,78	high_impact	4,21	damaging	0,58	damaging	0,07	deleterious	3,43	23	0,26	0,45	disease	0,84	disease	0,82	disease	0,85	disease	0,85	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,07	high_impact	2,64	0,33	0,8	25,54	7,33	N	0,4	N	0,97	polymorphism	0,99	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12539	12539	G	C	MI.19665	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	203	68	W	S	tGa/tCa	2,71	0,99	0	probably_damaging	1	neutral	0,48	neutral	0,44	deleterious	-6,92	deleterious	-13,78	high_impact	3,87	damaging	0,57	damaging	0,07	deleterious	3,82	23,4	0,25	0,45	disease	0,8	disease	0,84	disease	0,79	disease	0,84	7	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,21	high_impact	2,33	0,24	0,8	25,54	7,33	N	0,46	N	0,95	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12539	12539	G	T	MI.19666	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	203	68	W	L	tGa/tTa	2,71	0,99	0	probably_damaging	1	neutral	0,71	neutral	0,61	deleterious	-3,23	deleterious	-12,8	medium_impact	2,24	damaging	0,5	damaging	0,09	deleterious	4,08	23,7	0,27	0,45	disease	0,67	disease	0,62	disease	0,63	neutral	0,46	1	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,45	medium_impact	0,84	0,28	0,8	25,54	7,33	N	0,36	N	0,97	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12540	12540	A	T	MI.19667	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	204	68	W	C	tgA/tgT	5,46	1	0	probably_damaging	1	neutral	0,19	neutral	0,44	deleterious	-8,05	deleterious	-12,8	high_impact	4,21	damaging	0,55	damaging	0,05	deleterious	3,98	23,6	0,25	0,45	disease	0,93	disease	0,84	disease	0,77	disease	0,87	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,12	high_impact	2,64	0,3	0,8	25,54	7,33	N	0,48	N	0,98	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12540	12540	A	C	MI.19668	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	204	68	W	C	tgA/tgC	5,46	1	0	probably_damaging	1	neutral	0,19	neutral	0,44	deleterious	-8,05	deleterious	-12,8	high_impact	4,21	damaging	0,55	damaging	0,05	deleterious	3,88	23,5	0,25	0,45	disease	0,93	disease	0,84	disease	0,77	disease	0,87	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,12	high_impact	2,64	0,3	0,8	25,54	7,33	N	0,48	N	0,98	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12541	12541	G	T	MI.19669	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	205	69	A	S	Gcc/Tcc	2,25	0,95	0	benign	0,27	neutral	0,53	neutral	1,53	neutral	-1,12	neutral	-0,61	neutral_impact	0,18	neutral	0,79	neutral	0,76	neutral	1,74	14,63	0,47	0,55	disease	0,5	neutral	0,2	neutral	0,19	neutral	0,19	6	neutral	0,37	deleterious	0,63	neutral	-6	neutral	0,3	medium_impact	-0,34	medium_impact	0,26	low_impact	-1,04	0,89	0,9	28,03	15,07	N	0,4	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5944	5944	A	T	MI.1967	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	41	14	D	V	gAc/gTc	9,38	1	0	probably_damaging	1	deleterious	0,04	neutral	-1,24	neutral	-1,41	neutral	-1,76	medium_impact	2,8	damaging	0,58	damaging	0,06	deleterious	3,5	23,1	0,27	0,55	neutral	0,3	disease	0,93	disease	0,64	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-3,58	medium_impact	-0,58	medium_impact	1,49	0,38	0,9	1,56	6,7	N	0,43	N	0,93	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12541	12541	G	A	MI.19670	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	205	69	A	T	Gcc/Acc	2,25	0,95	0	benign	0,01	neutral	0,65	neutral	1,55	neutral	-0,74	neutral	0,1	neutral_impact	-0,9	neutral	0,89	neutral	0,94	deleterious	0,82	9,59	0,49	0,55	neutral	0,45	neutral	0,14	neutral	0,18	neutral	0,31	4	neutral	0,33	deleterious	0,82	neutral	-6	neutral	0,13	medium_impact	1,15	medium_impact	0,38	low_impact	-2,03	0,68	0,85	28,03	15,07	N	0,41	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12541	12541	G	C	MI.19671	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	205	69	A	P	Gcc/Ccc	2,25	0,95	0	possibly_damaging	0,73	neutral	0,17	neutral	1,5	neutral	-2,66	neutral	-1,59	low_impact	0,8	neutral	0,7	neutral	0,47	deleterious	3,45	23	0,18	0,45	disease	0,72	disease	0,65	neutral	0,47	neutral	0,49	0	neutral	0,87	neutral	0,22	neutral	-3	deleterious	0,72	low_impact	-1,16	medium_impact	-0,15	medium_impact	-0,47	0,83	0,9	28,03	15,07	N	0,42	N	0,38	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12542	12542	C	A	MI.19672	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	206	69	A	D	gCc/gAc	-0,73	0	0	possibly_damaging	0,66	neutral	0,16	neutral	1,5	deleterious	-3,27	neutral	-2,28	low_impact	1,15	neutral	0,69	neutral	0,47	deleterious	4,08	23,7	0,25	0,45	disease	0,78	disease	0,51	disease	0,65	disease	0,69	4	neutral	0,86	neutral	0,25	neutral	-3	deleterious	0,63	low_impact	-1,02	medium_impact	-0,17	medium_impact	-0,15	0,74	0,85	28,03	15,07	N	0,32	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12542	12542	C	T	MI.19673	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	206	69	A	V	gCc/gTc	-0,73	0	0	benign	0,02	neutral	0,46	neutral	1,75	neutral	1,51	neutral	2,34	neutral_impact	-0,67	neutral	0,88	neutral	0,95	neutral	1,42	12,88	0,42	0,55	neutral	0,2	neutral	0,18	neutral	0,22	neutral	0,32	4	neutral	0,52	deleterious	0,72	neutral	-6	neutral	0,3	medium_impact	0,86	medium_impact	0,19	low_impact	-1,82	0,86	0,9	28,03	15,07	N	0,32	N	0,04	polymorphism	1	0	rs201922401	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12542	12542	C	G	MI.19674	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	206	69	A	G	gCc/gGc	-0,73	0	0	benign	0,34	neutral	0,3	neutral	1,51	neutral	-2,13	deleterious	-2,51	low_impact	1,15	neutral	0,74	neutral	0,62	deleterious	2,14	17,12	0,31	0,45	neutral	0,22	neutral	0,24	neutral	0,45	neutral	0,42	2	neutral	0,64	deleterious	0,48	neutral	-6	neutral	0,38	medium_impact	-0,47	medium_impact	0,03	medium_impact	-0,15	0,77	0,85	28,03	15,07	N	0,41	N	0,44	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12544	12544	A	T	MI.19675	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	208	70	T	S	Aca/Tca	-0,27	0	0	possibly_damaging	0,44	neutral	0,47	neutral	1,62	neutral	0,35	deleterious	-2,96	neutral_impact	0,38	neutral	0,84	neutral	0,98	deleterious	0,09	3,49	0,48	0,55	disease	0,52	neutral	0,2	neutral	0,27	neutral	0,28	4	neutral	0,49	deleterious	0,52	neutral	-3	deleterious	0,45	medium_impact	-0,65	medium_impact	0,2	medium_impact	-0,86	0,62	0,8	19,57	13,89	N	0,35	N	0,32	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12544	12544	A	G	MI.19676	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	208	70	T	A	Aca/Gca	-0,27	0	0	benign	0,02	neutral	0,49	neutral	1,54	neutral	-0,6	deleterious	-4,14	medium_impact	2,44	neutral	0,85	neutral	0,71	neutral	1,34	12,46	0,62	0,65	neutral	0,47	neutral	0,28	neutral	0,47	neutral	0,46	1	neutral	0,49	deleterious	0,74	neutral	-3	neutral	0,16	medium_impact	0,86	medium_impact	0,22	medium_impact	1,03	0,44	0,8	19,57	13,89	N	0,39	N	0,86	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12544	12544	A	C	MI.19677	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	208	70	T	P	Aca/Cca	-0,27	0	0	possibly_damaging	0,81	neutral	0,2	neutral	1,52	neutral	-0,94	deleterious	-5,15	medium_impact	2,36	neutral	0,8	neutral	0,67	deleterious	3,17	22,7	0,2	0,45	disease	0,77	disease	0,74	disease	0,57	disease	0,7	4	neutral	0,89	neutral	0,2	NA	0	deleterious	0,78	low_impact	-1,34	medium_impact	-0,1	medium_impact	0,95	0,5	0,8	19,57	13,89	N	0,3	N	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12545	12545	C	T	MI.19678	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	209	70	T	M	aCa/aTa	0,18	0	0	benign	0,16	neutral	0,27	neutral	1,46	neutral	-2,96	deleterious	-5,14	medium_impact	2,13	neutral	0,85	neutral	0,67	deleterious	3,77	23,4	0,37	0,5	neutral	0,42	neutral	0,35	neutral	0,36	neutral	0,47	1	neutral	0,68	deleterious	0,56	neutral	-3	deleterious	0,67	medium_impact	-0,06	medium_impact	-0,01	medium_impact	0,74	0,7	0,85	19,57	13,89	N	0,42	N	0,45	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12545	12545	C	A	MI.19679	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	209	70	T	K	aCa/aAa	0,18	0	0	possibly_damaging	0,64	neutral	0,28	neutral	1,55	neutral	-0,38	deleterious	-5,02	medium_impact	2,13	neutral	0,76	neutral	0,57	deleterious	4	23,6	0,29	0,45	disease	0,64	disease	0,51	disease	0,53	disease	0,53	1	neutral	0,75	neutral	0,32	NA	0	deleterious	0,65	medium_impact	-0,98	medium_impact	0,01	medium_impact	0,74	0,65	0,8	19,57	13,89	N	0,35	N	0,91	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5944	5944	A	G	MI.1968	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	41	14	D	G	gAc/gGc	9,38	1	0	probably_damaging	1	deleterious	0,01	neutral	-1,22	neutral	-1,86	neutral	-1,35	high_impact	3,99	neutral	0,64	damaging	0,06	deleterious	3,76	23,3	0,29	0,55	neutral	0,44	disease	0,9	disease	0,64	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,58	medium_impact	-0,92	high_impact	2,59	0,56	0,9	1,56	6,7	P	0,49	N	0,85	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12547	12547	A	T	MI.19680	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	211	71	T	S	Acc/Tcc	-7,61	0	0	benign	0,36	neutral	0,4	neutral	1,57	neutral	-0,11	neutral	-1,05	low_impact	1,12	neutral	0,78	neutral	0,81	deleterious	2,07	16,69	0,53	0,6	neutral	0,44	neutral	0,26	disease	0,55	neutral	0,48	0	neutral	0,53	deleterious	0,52	neutral	-6	deleterious	0,44	medium_impact	-0,51	medium_impact	0,14	medium_impact	-0,18	0,63	0,8	13,76	13,42	N	0,35	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12547	12547	A	C	MI.19681	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	211	71	T	P	Acc/Ccc	-7,61	0	0	possibly_damaging	0,83	neutral	0,2	neutral	1,41	deleterious	-3,62	neutral	-2,03	medium_impact	2	neutral	0,67	neutral	0,43	deleterious	3,71	23,3	0,21	0,45	disease	0,79	disease	0,8	disease	0,67	disease	0,77	5	neutral	0,9	neutral	0,19	NA	0	deleterious	0,78	low_impact	-1,4	medium_impact	-0,1	medium_impact	0,62	0,53	0,8	13,76	13,42	N	0,27	N	0,76	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12547	12547	A	G	MI.19682	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	211	71	T	A	Acc/Gcc	-7,61	0	0	benign	0,01	neutral	0,5	neutral	1,49	neutral	-1,02	neutral	-0,19	low_impact	1,73	neutral	0,86	neutral	0,78	deleterious	1,87	15,41	0,69	0,75	neutral	0,41	neutral	0,34	disease	0,56	neutral	0,49	0	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,14	medium_impact	1,15	medium_impact	0,23	medium_impact	0,38	0,3	0,8	13,76	13,42	N	0,35	N	0,1	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12548	12548	C	G	MI.19683	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	212	71	T	S	aCc/aGc	2,94	0,02	0	benign	0,36	neutral	0,4	neutral	1,57	neutral	-0,11	neutral	-1,05	low_impact	1,12	neutral	0,78	neutral	0,81	neutral	1,76	14,77	0,53	0,6	neutral	0,44	neutral	0,26	disease	0,55	neutral	0,48	0	neutral	0,53	deleterious	0,52	neutral	-6	deleterious	0,44	medium_impact	-0,51	medium_impact	0,14	medium_impact	-0,18	0,63	0,8	13,76	13,42	N	0,37	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12548	12548	C	T	MI.19684	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	212	71	T	I	aCc/aTc	2,94	0,02	0	benign	0,01	neutral	0,39	neutral	1,58	neutral	-0,03	neutral	4	neutral_impact	-0,4	neutral	0,88	neutral	0,98	deleterious	0,84	9,7	0,43	0,55	neutral	0,3	neutral	0,19	neutral	0,28	neutral	0,36	3	neutral	0,6	deleterious	0,69	neutral	-6	deleterious	0,55	medium_impact	1,15	medium_impact	0,13	low_impact	-1,57	0,56	0,8	13,76	13,42	N	0,36	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12548	12548	C	A	MI.19685	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	212	71	T	N	aCc/aAc	2,94	0,02	0	possibly_damaging	0,81	neutral	0,31	neutral	1,49	neutral	-1,01	neutral	-2,05	low_impact	1,87	neutral	0,75	neutral	0,73	deleterious	3,5	23,1	0,57	0,65	disease	0,73	disease	0,62	disease	0,68	disease	0,58	2	neutral	0,84	neutral	0,25	neutral	-3	deleterious	0,68	low_impact	-1,34	medium_impact	0,04	medium_impact	0,51	0,66	0,8	13,76	13,42	N	0,36	N	0,61	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12550	12550	C	A	MI.19686	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	214	72	Q	K	Caa/Aaa	-6,01	0	0	probably_damaging	1	neutral	0,3	neutral	1,56	neutral	-0,3	deleterious	-3,01	medium_impact	2,31	neutral	0,78	neutral	0,43	deleterious	2,75	21,1	0,56	0,6	neutral	0,22	neutral	0,29	neutral	0,49	neutral	0,43	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,66	low_impact	-3,6	medium_impact	0,03	medium_impact	0,91	0,53	0,8	22,89	16,75	N	0,35	N	0,62	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12550	12550	C	G	MI.19687	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	214	72	Q	E	Caa/Gaa	-6,01	0	0	probably_damaging	1	neutral	0,29	neutral	1,62	neutral	0,29	neutral	-2,13	low_impact	1,72	neutral	0,81	neutral	0,73	neutral	1,76	14,74	0,62	0,65	neutral	0,4	neutral	0,22	neutral	0,5	neutral	0,41	2	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	0,02	medium_impact	0,37	0,62	0,8	22,89	16,75	N	0,36	N	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12551	12551	A	T	MI.19688	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	215	72	Q	L	cAa/cTa	-1,42	0	0	probably_damaging	1	neutral	0,67	neutral	1,47	neutral	-2,2	deleterious	-5,76	low_impact	1,82	neutral	0,75	neutral	0,76	deleterious	2,13	17,07	0,35	0,5	neutral	0,27	neutral	0,21	neutral	0,3	neutral	0,37	3	deleterious	1	neutral	0,34	neutral	-2	deleterious	0,66	low_impact	-3,6	medium_impact	0,4	medium_impact	0,46	0,24	0,8	22,89	16,75	N	0,31	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12551	12551	A	C	MI.19689	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	215	72	Q	P	cAa/cCa	-1,42	0	0	probably_damaging	1	neutral	0,21	neutral	1,47	neutral	-1,97	deleterious	-4,78	medium_impact	2,19	neutral	0,72	neutral	0,7	deleterious	3,07	22,4	0,24	0,45	disease	0,55	disease	0,59	disease	0,52	neutral	0,48	0	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	-0,09	medium_impact	0,8	0,36	0,8	22,89	16,75	N	0,34	N	0,96	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5945	5945	C	A	MI.1969	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	42	14	D	E	gaC/gaA	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	-1,19	neutral	-0,53	neutral	-0,77	high_impact	3,64	damaging	0,55	damaging	0,07	deleterious	4,04	23,7	0,54	0,6	neutral	0,2	disease	0,84	neutral	0,47	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	high_impact	2,26	0,69	0,9	1,56	6,7	P	0,51	P	0,65	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12551	12551	A	G	MI.19690	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	215	72	Q	R	cAa/cGa	-1,42	0	0	probably_damaging	1	neutral	0,35	neutral	1,5	neutral	-1,28	deleterious	-2,84	medium_impact	3	neutral	0,76	neutral	0,44	deleterious	2,2	17,51	0,57	0,65	disease	0,5	neutral	0,31	disease	0,53	neutral	0,34	3	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,71	low_impact	-3,6	medium_impact	0,08	medium_impact	1,54	0,43	0,8	22,89	16,75	N	0,36	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12552	12552	A	T	MI.19691	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	216	72	Q	H	caA/caT	-0,73	0	0	probably_damaging	1	neutral	0,55	neutral	1,47	neutral	-1,98	neutral	-2,11	low_impact	1,75	neutral	0,78	neutral	0,96	deleterious	1,85	15,28	0,62	0,65	disease	0,67	neutral	0,17	neutral	0,3	neutral	0,43	1	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,28	medium_impact	0,4	0,59	0,8	22,89	16,75	N	0,29	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12552	12552	A	C	MI.19692	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	216	72	Q	H	caA/caC	-0,73	0	0	probably_damaging	1	neutral	0,55	neutral	1,47	neutral	-1,98	neutral	-2,11	low_impact	1,75	neutral	0,78	neutral	0,96	neutral	1,62	13,99	0,62	0,65	disease	0,67	neutral	0,17	neutral	0,3	neutral	0,43	1	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,28	medium_impact	0,4	0,59	0,8	22,89	16,75	N	0,29	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12553	12553	A	T	MI.19693	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	217	73	T	S	Aca/Tca	-3,26	0	0	benign	0,18	neutral	0,43	neutral	1,71	neutral	1,27	deleterious	-2,6	low_impact	0,87	neutral	0,9	neutral	0,96	neutral	1,68	14,32	0,55	0,6	NA	NA	neutral	0,22	neutral	0,3	neutral	0,19	6	neutral	0,48	deleterious	0,63	neutral	-6	deleterious	0,7	medium_impact	-0,12	medium_impact	0,17	medium_impact	-0,41	0,64	0,8	12,77	11,07	N	0,45	N	0,15	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12553	12553	A	C	MI.19694	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	217	73	T	P	Aca/Cca	-3,26	0	0	probably_damaging	0,97	neutral	0,2	neutral	1,55	neutral	-0,73	deleterious	-5,06	medium_impact	2,04	neutral	0,8	neutral	0,62	deleterious	3,24	22,8	0,22	0,45	NA	NA	disease	0,71	neutral	0,5	disease	0,53	1	deleterious	0,98	neutral	0,12	deleterious	1	deleterious	0,78	low_impact	-2,18	medium_impact	-0,1	medium_impact	0,66	0,44	0,8	12,77	11,07	N	0,32	N	0,98	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12553	12553	A	G	MI.19695	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	217	73	T	A	Aca/Gca	-3,26	0	0	possibly_damaging	0,73	neutral	0,48	neutral	1,66	neutral	0,87	deleterious	-3,98	medium_impact	2,54	neutral	0,77	neutral	0,62	deleterious	3,17	22,7	0,61	0,65	NA	NA	neutral	0,27	disease	0,53	neutral	0,35	3	neutral	0,71	neutral	0,38	NA	0	deleterious	0,72	low_impact	-1,16	medium_impact	0,21	medium_impact	1,12	0,51	0,8	12,77	11,07	N	0,33	N	0,7	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12554	12554	C	T	MI.19696	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	218	73	T	M	aCa/aTa	0,18	0	0	probably_damaging	0,99	neutral	0,24	neutral	1,53	neutral	-1,19	deleterious	-5,09	medium_impact	2,7	neutral	0,77	neutral	0,65	deleterious	2,74	21	0,38	0,5	NA	NA	neutral	0,35	neutral	0,38	neutral	0,18	6	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,71	low_impact	-2,64	medium_impact	-0,04	medium_impact	1,26	0,7	0,85	12,77	11,07	N	0,4	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12554	12554	C	A	MI.19697	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	218	73	T	K	aCa/aAa	0,18	0	0	possibly_damaging	0,88	neutral	0,31	neutral	1,59	neutral	0,06	deleterious	-4,86	medium_impact	3,4	neutral	0,76	neutral	0,38	deleterious	4,37	24,1	0,35	0,5	NA	NA	disease	0,6	disease	0,74	disease	0,75	5	neutral	0,9	neutral	0,22	NA	0	deleterious	0,76	low_impact	-1,57	medium_impact	0,04	medium_impact	1,9	0,64	0,8	12,77	11,07	N	0,38	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12556	12556	A	G	MI.19698	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	220	74	T	A	Acc/Gcc	-10,14	0	0	benign	0,08	neutral	0,53	neutral	1,59	neutral	0,15	neutral	-0,39	low_impact	1,43	neutral	0,78	neutral	0,77	deleterious	1,97	16,03	0,63	0,7	NA	NA	neutral	0,23	disease	0,53	neutral	0,31	4	neutral	0,4	deleterious	0,73	neutral	-6	neutral	0,21	medium_impact	0,26	medium_impact	0,26	medium_impact	0,1	0,34	0,8	18,91	11,5	N	0,31	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12556	12556	A	T	MI.19699	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	220	74	T	S	Acc/Tcc	-10,14	0	0	benign	0,36	neutral	0,5	neutral	1,55	neutral	-0,91	neutral	-0,94	neutral_impact	0,76	neutral	0,74	neutral	0,83	deleterious	2,06	16,57	0,52	0,6	NA	NA	neutral	0,23	neutral	0,5	neutral	0,17	7	neutral	0,42	deleterious	0,57	neutral	-6	neutral	0,41	medium_impact	-0,51	medium_impact	0,23	medium_impact	-0,51	0,55	0,8	18,91	11,5	N	0,39	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8618	8618	T	G	MI.197	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	92	31	I	S	aTc/aGc	-0,33	0	0,01	benign	0,22	neutral	0,08	neutral	4,37	neutral	-1,3	neutral	-2,5	low_impact	1,75	neutral	0,83	neutral	0,52	deleterious	2,33	18,39	0,37	0,65	neutral	0,45	disease	0,65	neutral	0,24	disease	0,52	0	neutral	0,91	neutral	0,43	neutral	-6	neutral	0,29	medium_impact	-0,23	medium_impact	-0,31	medium_impact	0,4	0,35	0,9	28,32	22,32	N	0,36	N	0,42	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5945	5945	C	G	MI.1970	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	42	14	D	E	gaC/gaG	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	-1,19	neutral	-0,53	neutral	-0,77	high_impact	3,64	damaging	0,55	damaging	0,07	deleterious	3,71	23,3	0,54	0,6	neutral	0,2	disease	0,84	neutral	0,47	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	high_impact	2,26	0,69	0,9	1,56	6,7	P	0,51	P	0,65	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12556	12556	A	C	MI.19700	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	220	74	T	P	Acc/Ccc	-10,14	0	0	possibly_damaging	0,58	neutral	0,23	neutral	1,52	neutral	-2,45	neutral	-2,03	medium_impact	2,12	neutral	0,64	neutral	0,39	deleterious	3,57	23,1	0,24	0,45	NA	NA	disease	0,72	neutral	0,48	disease	0,52	0	neutral	0,77	neutral	0,33	NA	0	deleterious	0,68	medium_impact	-0,88	medium_impact	-0,06	medium_impact	0,73	0,51	0,8	18,91	11,5	N	0,34	N	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12557	12557	C	T	MI.19701	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	221	74	T	I	aCc/aTc	-1,19	0	0,01	benign	0	neutral	0,47	neutral	1,66	neutral	0,99	neutral	2,1	neutral_impact	0,27	neutral	0,87	neutral	0,96	deleterious	0,48	7,28	0,44	0,55	NA	NA	neutral	0,37	neutral	0,25	neutral	0,17	7	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,16	high_impact	2,1	medium_impact	0,2	medium_impact	-0,96	0,52	0,8	18,91	11,5	N	0,3	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12557	12557	C	A	MI.19702	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	221	74	T	N	aCc/aAc	-1,19	0	0,01	possibly_damaging	0,58	neutral	0,37	neutral	1,52	neutral	-2,15	neutral	-1,93	medium_impact	2,12	neutral	0,66	neutral	0,62	deleterious	3,33	22,9	0,57	0,65	NA	NA	disease	0,58	disease	0,53	disease	0,59	2	neutral	0,65	neutral	0,4	NA	0	deleterious	0,61	medium_impact	-0,88	medium_impact	0,11	medium_impact	0,73	0,66	0,8	18,91	11,5	N	0,34	N	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12557	12557	C	G	MI.19703	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	221	74	T	S	aCc/aGc	-1,19	0	0,01	benign	0,36	neutral	0,5	neutral	1,55	neutral	-0,91	neutral	-0,94	neutral_impact	0,76	neutral	0,74	neutral	0,83	neutral	1,74	14,66	0,52	0,6	NA	NA	neutral	0,23	neutral	0,5	neutral	0,17	7	neutral	0,42	deleterious	0,57	neutral	-6	neutral	0,41	medium_impact	-0,51	medium_impact	0,23	medium_impact	-0,51	0,55	0,8	18,91	11,5	N	0,39	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12559	12559	C	G	MI.19704	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	223	75	Q	E	Cag/Gag	-3,94	0	0	benign	0	neutral	0,32	neutral	1,63	neutral	0,76	neutral	0,01	neutral_impact	-0,51	neutral	0,9	neutral	0,96	neutral	-0,35	0,5	0,59	0,65	NA	NA	neutral	0,34	neutral	0,25	neutral	0,17	7	neutral	0,68	deleterious	0,66	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,05	low_impact	-1,67	0,57	0,8	26,87	19,98	N	0,39	N	0,2	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12559	12559	C	A	MI.19705	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	223	75	Q	K	Cag/Aag	-3,94	0	0	benign	0,01	neutral	0,33	neutral	1,72	neutral	1,61	neutral	2,41	neutral_impact	-1,31	neutral	0,8	neutral	0,93	neutral	-0,45	0,29	0,68	0,7	NA	NA	neutral	0,14	neutral	0,22	neutral	0,21	6	neutral	0,66	deleterious	0,66	neutral	-6	neutral	0,27	medium_impact	1,15	medium_impact	0,06	low_impact	-2,4	0,56	0,8	26,87	19,98	N	0,34	N	0,14	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12560	12560	A	G	MI.19706	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	224	75	Q	R	cAg/cGg	-0,27	0	0	benign	0,18	neutral	0,36	neutral	1,58	neutral	-0,2	neutral	0,43	low_impact	1,15	neutral	0,69	neutral	0,47	neutral	1,67	14,21	0,73	0,75	NA	NA	neutral	0,46	disease	0,55	neutral	0,4	2	neutral	0,57	deleterious	0,59	neutral	-6	deleterious	0,45	medium_impact	-0,12	medium_impact	0,1	medium_impact	-0,15	0,4	0,8	26,87	19,98	N	0,4	N	0,29	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12560	12560	A	T	MI.19707	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	224	75	Q	L	cAg/cTg	-0,27	0	0	benign	0,29	neutral	0,66	neutral	1,6	neutral	0,24	deleterious	-3,05	low_impact	0,8	neutral	0,78	neutral	0,56	deleterious	3,4	23	0,4	0,5	NA	NA	neutral	0,43	neutral	0,48	neutral	0,21	6	neutral	0,25	deleterious	0,69	neutral	-6	deleterious	0,51	medium_impact	-0,38	medium_impact	0,39	medium_impact	-0,47	0,23	0,8	26,87	19,98	N	0,22	N	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12560	12560	A	C	MI.19708	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	224	75	Q	P	cAg/cCg	-0,27	0	0	benign	0,36	neutral	0,21	neutral	1,54	neutral	-1,64	neutral	-2,05	neutral_impact	0,34	neutral	0,71	neutral	0,72	deleterious	2,96	22,1	0,23	0,45	NA	NA	disease	0,71	neutral	0,31	disease	0,52	0	neutral	0,75	neutral	0,43	neutral	-6	deleterious	0,63	medium_impact	-0,51	medium_impact	-0,09	medium_impact	-0,89	0,41	0,8	26,87	19,98	N	0,36	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12561	12561	G	T	MI.19709	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	225	75	Q	H	caG/caT	2,25	0	0,01	possibly_damaging	0,65	neutral	0,53	neutral	1,64	neutral	0,81	neutral	-1,13	neutral_impact	0,6	neutral	0,74	neutral	0,71	deleterious	2,27	17,97	0,64	0,7	NA	NA	neutral	0,26	neutral	0,4	neutral	0,15	7	neutral	0,61	neutral	0,44	neutral	-3	deleterious	0,64	low_impact	-1	medium_impact	0,26	medium_impact	-0,66	0,68	0,85	26,87	19,98	N	0,33	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5946	5946	A	C	MI.1971	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	43	15	I	L	Att/Ctt	-2,88	0	0	probably_damaging	0,97	deleterious	0	neutral	-0,43	neutral	-2,88	neutral	-0,42	medium_impact	3,3	damaging	0,58	damaging	0,16	deleterious	3,42	23	0,34	0,55	neutral	0,35	disease	0,79	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,69	low_impact	-2,18	low_impact	-1,48	medium_impact	1,95	0,78	0,9	1,17	6,73	N	0,35	N	0,61	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12561	12561	G	C	MI.19710	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	225	75	Q	H	caG/caC	2,25	0	0,01	possibly_damaging	0,65	neutral	0,53	neutral	1,64	neutral	0,81	neutral	-1,13	neutral_impact	0,6	neutral	0,74	neutral	0,71	deleterious	2,15	17,2	0,64	0,7	NA	NA	neutral	0,26	neutral	0,4	neutral	0,15	7	neutral	0,61	neutral	0,44	neutral	-3	deleterious	0,64	low_impact	-1	medium_impact	0,26	medium_impact	-0,66	0,68	0,85	26,87	19,98	N	0,33	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12562	12562	C	T	MI.19711	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	226	76	L	F	Ctc/Ttc	-2,8	0	0,02	probably_damaging	0,98	neutral	0,84	neutral	1,43	neutral	-1,01	deleterious	-3,4	medium_impact	2,25	neutral	0,83	neutral	0,56	deleterious	3,75	23,3	0,4	0,5	NA	NA	disease	0,53	neutral	0,44	neutral	0,46	1	neutral	0,98	neutral	0,43	deleterious	1	deleterious	0,75	low_impact	-2,35	medium_impact	0,63	medium_impact	0,85	0,7	0,85	9,12	10,32	N	0,19	N	0,86	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12562	12562	C	A	MI.19712	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	226	76	L	I	Ctc/Atc	-2,8	0	0,02	benign	0,38	neutral	0,48	neutral	1,63	neutral	0,28	neutral	-1,33	neutral_impact	0,5	neutral	0,78	neutral	0,9	deleterious	1,93	15,76	0,38	0,5	NA	NA	neutral	0,03	neutral	0,16	neutral	0,19	6	neutral	0,45	deleterious	0,55	neutral	-6	deleterious	0,68	medium_impact	-0,54	medium_impact	0,21	medium_impact	-0,75	0,8	0,85	9,12	10,32	N	0,45	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12562	12562	C	G	MI.19713	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	226	76	L	V	Ctc/Gtc	-2,8	0	0,02	possibly_damaging	0,76	neutral	0,5	neutral	1,59	neutral	-0,57	neutral	-2,29	low_impact	1,8	neutral	0,73	neutral	0,78	deleterious	2,05	16,53	0,34	0,5	NA	NA	neutral	0,19	neutral	0,27	neutral	0,2	6	neutral	0,74	neutral	0,37	neutral	-3	deleterious	0,7	low_impact	-1,22	medium_impact	0,23	medium_impact	0,44	0,68	0,85	9,12	10,32	N	0,35	N	0,62	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12563	12563	T	A	MI.19714	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	227	76	L	H	cTc/cAc	-1,88	0	0	probably_damaging	1	neutral	0,5	neutral	1,33	deleterious	-4,71	deleterious	-6,42	high_impact	3,61	neutral	0,73	neutral	0,43	deleterious	4,04	23,7	0,15	0,4	NA	NA	disease	0,65	disease	0,68	disease	0,72	4	deleterious	0,99	neutral	0,25	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,23	high_impact	2,1	0,56	0,8	9,12	10,32	N	0,29	N	0,85	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12563	12563	T	C	MI.19715	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	227	76	L	P	cTc/cCc	-1,88	0	0	probably_damaging	1	neutral	0,19	neutral	1,33	deleterious	-3,82	deleterious	-6,49	medium_impact	3,27	damaging	0,57	neutral	0,3	deleterious	3,75	23,3	0,11	0,4	NA	NA	disease	0,85	disease	0,6	disease	0,78	6	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,89	low_impact	-3,6	medium_impact	-0,12	medium_impact	1,78	0,55	0,8	9,12	10,32	N	0,3	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12563	12563	T	G	MI.19716	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	227	76	L	R	cTc/cGc	-1,88	0	0	probably_damaging	1	neutral	0,33	neutral	1,34	deleterious	-4,02	deleterious	-5,65	high_impact	3,61	neutral	0,68	neutral	0,36	deleterious	4,06	23,7	0,11	0,4	NA	NA	disease	0,84	disease	0,73	disease	0,8	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,06	high_impact	2,1	0,56	0,8	9,12	10,32	N	0,3	N	0,96	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12565	12565	T	G	MI.19717	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	229	77	S	A	Tcc/Gcc	-7,38	0	0	possibly_damaging	0,45	neutral	0,75	neutral	1,46	neutral	-1,32	neutral	-1,94	medium_impact	2,42	neutral	0,86	neutral	0,77	deleterious	3,48	23,1	0,43	0,55	NA	NA	neutral	0,28	neutral	0,49	neutral	0,18	6	neutral	0,35	deleterious	0,65	NA	0	deleterious	0,72	medium_impact	-0,66	medium_impact	0,5	medium_impact	1,01	0,74	0,85	11,94	12,21	N	0,28	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12565	12565	T	A	MI.19718	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	229	77	S	T	Tcc/Acc	-7,38	0	0	benign	0,04	neutral	0,58	neutral	1,45	neutral	-1,42	neutral	-0,66	neutral_impact	0,52	neutral	0,9	neutral	0,99	deleterious	1,96	15,97	0,29	0,45	NA	NA	neutral	0,23	neutral	0,31	neutral	0,17	7	neutral	0,37	deleterious	0,77	neutral	-6	deleterious	0,71	medium_impact	0,57	medium_impact	0,31	medium_impact	-0,73	0,79	0,85	11,94	12,21	N	0,38	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12565	12565	T	C	MI.19719	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	229	77	S	P	Tcc/Ccc	-7,38	0	0	possibly_damaging	0,86	neutral	0,29	neutral	1,43	neutral	-1,86	deleterious	-3,52	low_impact	1,49	neutral	0,76	neutral	0,8	deleterious	3,79	23,4	0,2	0,45	NA	NA	disease	0,7	neutral	0,35	disease	0,52	0	neutral	0,89	neutral	0,22	neutral	-3	deleterious	0,81	low_impact	-1,5	medium_impact	0,02	medium_impact	0,16	0,69	0,85	11,94	12,21	N	0,36	N	0,86	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5946	5946	A	G	MI.1972	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	43	15	I	V	Att/Gtt	-2,88	0	0	probably_damaging	0,92	deleterious	0,04	neutral	-0,37	neutral	-2,22	neutral	-0,21	high_impact	3,65	neutral	0,65	damaging	0,15	deleterious	2,7	20,8	0,51	0,6	neutral	0,3	disease	0,56	disease	0,57	disease	0,65	3	deleterious	0,99	neutral	0,06	deleterious	6	deleterious	0,62	low_impact	-1,76	medium_impact	-0,58	high_impact	2,27	0,64	0,9	1,17	6,73	N	0,44	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12566	12566	C	A	MI.19720	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	230	77	S	Y	tCc/tAc	-1,88	0	0	probably_damaging	0,93	neutral	1	neutral	1,39	deleterious	-3,78	deleterious	-4,13	low_impact	1,92	neutral	0,79	neutral	0,77	deleterious	3,87	23,5	0,28	0,45	NA	NA	disease	0,61	neutral	0,47	neutral	0,47	1	neutral	0,93	deleterious	0,54	neutral	-2	deleterious	0,77	low_impact	-1,81	high_impact	1,89	medium_impact	0,55	0,74	0,85	11,94	12,21	N	0,19	N	0,93	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12566	12566	C	G	MI.19721	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	230	77	S	C	tCc/tGc	-1,88	0	0	probably_damaging	0,97	neutral	0,19	neutral	1,38	deleterious	-5,2	deleterious	-2,88	medium_impact	2,96	neutral	0,87	neutral	0,56	deleterious	3,42	23	0,36	0,5	NA	NA	disease	0,69	neutral	0,4	disease	0,51	0	neutral	0,98	neutral	0,11	deleterious	1	deleterious	0,76	low_impact	-2,18	medium_impact	-0,12	medium_impact	1,5	0,68	0,85	11,94	12,21	N	0,42	N	0,5	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12566	12566	C	T	MI.19722	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	230	77	S	F	tCc/tTc	-1,88	0	0	possibly_damaging	0,84	neutral	0,71	neutral	1,38	deleterious	-4,24	deleterious	-4,16	medium_impact	2,27	neutral	0,82	neutral	0,68	deleterious	3,04	22,4	0,24	0,45	NA	NA	disease	0,71	neutral	0,48	disease	0,51	0	neutral	0,81	neutral	0,44	NA	0	deleterious	0,77	low_impact	-1,43	medium_impact	0,45	medium_impact	0,87	0,38	0,8	11,94	12,21	N	0,23	N	0,92	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12568	12568	C	G	MI.19723	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	232	78	L	V	Cta/Gta	-20	0	0	possibly_damaging	0,9	neutral	0,48	neutral	1,49	neutral	-0,9	neutral	-1,71	medium_impact	2,3	neutral	0,86	neutral	0,87	deleterious	2,14	17,1	0,34	0,5	NA	NA	neutral	0,28	neutral	0,32	neutral	0,18	6	neutral	0,89	neutral	0,29	NA	0	deleterious	0,72	low_impact	-1,65	medium_impact	0,21	medium_impact	0,9	0,78	0,85	15,42	13,26	N	0,35	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12568	12568	C	A	MI.19724	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	232	78	L	M	Cta/Ata	-20	0	0	possibly_damaging	0,66	neutral	0,3	neutral	1,53	neutral	-0,45	neutral	-0,22	neutral_impact	0,6	neutral	0,85	neutral	0,96	neutral	1,34	12,49	0,28	0,45	NA	NA	neutral	0,16	neutral	0,22	neutral	0,21	6	neutral	0,75	neutral	0,32	neutral	-3	deleterious	0,7	low_impact	-1,02	medium_impact	0,03	medium_impact	-0,66	0,75	0,85	15,42	13,26	N	0,44	N	0,11	polymorphism	1	0,01	rs28411793	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12569	12569	T	G	MI.19725	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	233	78	L	R	cTa/cGa	-2,34	0	0	probably_damaging	0,98	neutral	0,34	neutral	1,39	deleterious	-3,52	deleterious	-4,55	high_impact	3,54	neutral	0,69	neutral	0,42	deleterious	4,01	23,6	0,08	0,35	NA	NA	disease	0,8	disease	0,72	disease	0,77	5	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,86	low_impact	-2,35	medium_impact	0,07	high_impact	2,03	0,56	0,8	15,42	13,26	N	0,34	N	0,85	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12569	12569	T	A	MI.19726	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	233	78	L	Q	cTa/cAa	-2,34	0	0	probably_damaging	0,99	neutral	0,28	neutral	1,39	deleterious	-3,67	deleterious	-4,22	high_impact	3,54	neutral	0,72	neutral	0,53	deleterious	3,93	23,5	0,11	0,4	NA	NA	disease	0,62	disease	0,61	disease	0,7	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,79	low_impact	-2,64	medium_impact	0,01	high_impact	2,03	0,79	0,85	15,42	13,26	N	0,39	N	0,79	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12569	12569	T	C	MI.19727	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	233	78	L	P	cTa/cCa	-2,34	0	0	probably_damaging	1	neutral	0,2	neutral	1,38	deleterious	-4,08	deleterious	-5,37	medium_impact	2,99	neutral	0,6	neutral	0,33	deleterious	3,76	23,4	0,09	0,35	NA	NA	disease	0,81	disease	0,6	disease	0,75	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,88	low_impact	-3,6	medium_impact	-0,1	medium_impact	1,53	0,68	0,85	15,42	13,26	N	0,29	N	0,97	polymorphism	1	0,05	.	.	.	.	.	.	COSM1155523	.	.	.	.	.	.	.	.
chrM	12571	12571	A	T	MI.19728	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	235	79	S	C	Agc/Tgc	-10,83	0	0	probably_damaging	0,99	neutral	0,18	neutral	1,37	deleterious	-5,27	deleterious	-4,78	high_impact	3,77	neutral	0,74	damaging	0,13	deleterious	3,27	22,8	0,26	0,45	NA	NA	disease	0,77	disease	0,7	disease	0,72	4	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,8	low_impact	-2,64	medium_impact	-0,13	high_impact	2,24	0,53	0,8	4,15	8,78	N	0,32	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12571	12571	A	C	MI.19729	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	235	79	S	R	Agc/Cgc	-10,83	0	0	probably_damaging	0,96	neutral	0,36	neutral	1,41	neutral	-1,86	deleterious	-4,33	high_impact	4,12	neutral	0,74	damaging	0,14	deleterious	3,69	23,3	0,18	0,45	NA	NA	disease	0,85	disease	0,81	disease	0,8	6	neutral	0,96	neutral	0,2	deleterious	2	deleterious	0,87	low_impact	-2,06	medium_impact	0,1	high_impact	2,56	0,75	0,85	4,15	8,78	N	0,44	N	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5946	5946	A	T	MI.1973	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	43	15	I	F	Att/Ttt	-2,88	0	0	probably_damaging	1	deleterious	0	neutral	-0,52	deleterious	-5,77	neutral	-0,83	high_impact	4,8	damaging	0,6	damaging	0,1	deleterious	3,39	23	0,22	0,55	disease	0,77	disease	0,87	disease	0,71	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,33	0,76	0,9	1,17	6,73	P	0,68	P	0,85	polymorphism	0,67	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12571	12571	A	G	MI.19730	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	235	79	S	G	Agc/Ggc	-10,83	0	0	possibly_damaging	0,73	neutral	0,34	neutral	1,55	neutral	0,06	deleterious	-3,49	medium_impact	2,73	neutral	0,65	damaging	0,24	deleterious	3,44	23	0,34	0,5	NA	NA	neutral	0,5	disease	0,64	neutral	0,45	1	neutral	0,77	neutral	0,31	NA	0	deleterious	0,76	low_impact	-1,16	medium_impact	0,07	medium_impact	1,29	0,7	0,85	4,15	8,78	N	0,32	N	0,86	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12572	12572	G	A	MI.19731	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	236	79	S	N	aGc/aAc	2,94	0,12	0	benign	0,12	neutral	0,32	neutral	1,46	neutral	-1,43	neutral	-1,77	low_impact	1,77	neutral	0,76	neutral	0,83	deleterious	2,37	18,62	0,53	0,6	NA	NA	disease	0,61	disease	0,64	neutral	0,46	1	neutral	0,63	deleterious	0,6	neutral	-6	deleterious	0,8	medium_impact	0,08	medium_impact	0,05	medium_impact	0,41	0,55	0,8	4,15	8,78	N	0,37	N	0,87	disease_causing	0,59	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12572	12572	G	C	MI.19732	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	236	79	S	T	aGc/aCc	2,94	0,12	0	possibly_damaging	0,86	neutral	0,41	neutral	1,43	neutral	-0,61	deleterious	-2,66	medium_impact	2,31	neutral	0,7	damaging	0,25	deleterious	3,25	22,8	0,27	0,45	NA	NA	neutral	0,48	disease	0,6	neutral	0,37	3	neutral	0,86	neutral	0,28	NA	0	deleterious	0,77	low_impact	-1,5	medium_impact	0,15	medium_impact	0,91	0,8	0,85	4,15	8,78	N	0,34	N	0,71	disease_causing	0,54	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12572	12572	G	T	MI.19733	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	236	79	S	I	aGc/aTc	2,94	0,12	0	probably_damaging	0,98	neutral	0,4	neutral	1,39	neutral	-2,92	deleterious	-5,61	medium_impact	3,42	neutral	0,7	damaging	0,13	deleterious	3,94	23,5	0,24	0,45	NA	NA	disease	0,83	disease	0,73	disease	0,76	5	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,83	low_impact	-2,35	medium_impact	0,14	medium_impact	1,92	0,87	0,9	4,15	8,78	N	0,33	N	0,99	disease_causing	0,92	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12574	12574	T	G	MI.19734	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	238	80	F	V	Ttc/Gtc	-1,19	0	0	possibly_damaging	0,81	neutral	0,51	neutral	0,96	deleterious	-3,84	deleterious	-5,45	high_impact	3,77	neutral	0,82	neutral	0,56	deleterious	4,02	23,6	0,25	0,45	NA	NA	disease	0,79	disease	0,66	disease	0,66	3	neutral	0,79	neutral	0,35	deleterious	1	deleterious	0,81	low_impact	-1,34	medium_impact	0,24	high_impact	2,24	0,72	0,85	4,15	10,6	N	0,31	N	0,95	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12574	12574	T	A	MI.19735	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	238	80	F	I	Ttc/Atc	-1,19	0	0	possibly_damaging	0,81	neutral	0,4	neutral	1,1	neutral	-1,99	deleterious	-4,46	medium_impact	2,19	neutral	0,8	neutral	0,76	deleterious	4,26	23,9	0,2	0,45	NA	NA	disease	0,64	neutral	0,49	neutral	0,47	1	neutral	0,82	neutral	0,3	NA	0	deleterious	0,78	low_impact	-1,34	medium_impact	0,14	medium_impact	0,8	0,76	0,85	4,15	10,6	N	0,31	N	0,95	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12574	12574	T	C	MI.19736	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	238	80	F	L	Ttc/Ctc	-1,19	0	0	benign	0,12	neutral	0,67	neutral	1,25	neutral	-1,16	deleterious	-4,23	medium_impact	2,02	neutral	0,82	neutral	0,9	deleterious	2,63	20,4	0,46	0,55	NA	NA	neutral	0,38	neutral	0,41	neutral	0,17	7	neutral	0,22	deleterious	0,78	neutral	-3	deleterious	0,73	medium_impact	0,08	medium_impact	0,4	medium_impact	0,64	0,81	0,85	4,15	10,6	N	0,31	N	0,92	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12575	12575	T	A	MI.19737	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	239	80	F	Y	tTc/tAc	0,87	0,69	0	probably_damaging	0,92	neutral	1	neutral	1,03	neutral	-2,65	deleterious	-2,61	high_impact	3,77	neutral	0,75	neutral	0,42	deleterious	4,12	23,8	0,23	0,45	NA	NA	disease	0,68	disease	0,73	disease	0,7	4	neutral	0,92	deleterious	0,54	deleterious	2	deleterious	0,81	low_impact	-1,75	high_impact	1,89	high_impact	2,24	0,77	0,85	4,15	10,6	N	0,32	N	0,88	polymorphism	0,92	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12575	12575	T	C	MI.19738	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	239	80	F	S	tTc/tCc	0,87	0,69	0	probably_damaging	0,97	neutral	0,43	neutral	0,92	deleterious	-5,55	deleterious	-6,84	high_impact	4,12	neutral	0,77	neutral	0,41	deleterious	4,13	23,8	0,14	0,4	NA	NA	disease	0,8	disease	0,71	disease	0,73	5	neutral	0,97	neutral	0,23	deleterious	2	deleterious	0,84	low_impact	-2,18	medium_impact	0,17	high_impact	2,56	0,54	0,8	4,15	10,6	N	0,36	N	0,97	polymorphism	0,57	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12575	12575	T	G	MI.19739	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	239	80	F	C	tTc/tGc	0,87	0,69	0	probably_damaging	0,99	neutral	0,18	neutral	0,91	deleterious	-6,71	deleterious	-6,66	high_impact	3,77	neutral	0,73	neutral	0,4	deleterious	3,98	23,6	0,19	0,45	NA	NA	disease	0,87	disease	0,74	disease	0,78	6	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,82	low_impact	-2,64	medium_impact	-0,13	high_impact	2,24	0,53	0,8	4,15	10,6	N	0,4	N	0,99	disease_causing	0,54	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5947	5947	T	C	MI.1974	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	44	15	I	T	aTt/aCt	7,07	1	0	probably_damaging	1	deleterious	0	neutral	-0,52	deleterious	-5,55	neutral	-1,05	high_impact	4,11	neutral	0,67	damaging	0,14	deleterious	3,25	22,8	0,33	0,55	disease	0,77	disease	0,82	disease	0,68	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,7	0,58	0,9	1,17	6,73	N	0,48	N	0,76	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12576	12576	C	G	MI.19740	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	240	80	F	L	ttC/ttG	7,3	0,98	0	benign	0,12	neutral	0,67	neutral	1,25	neutral	-1,16	deleterious	-4,23	medium_impact	2,02	neutral	0,82	neutral	0,9	deleterious	2,9	21,9	0,46	0,55	NA	NA	neutral	0,38	neutral	0,41	neutral	0,17	7	neutral	0,22	deleterious	0,78	neutral	-3	deleterious	0,73	medium_impact	0,08	medium_impact	0,4	medium_impact	0,64	0,81	0,85	4,15	10,6	P	0,55	P	0,92	disease_causing	0,8	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12576	12576	C	A	MI.19741	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	240	80	F	L	ttC/ttA	7,3	0,98	0	benign	0,12	neutral	0,67	neutral	1,25	neutral	-1,16	deleterious	-4,23	medium_impact	2,02	neutral	0,82	neutral	0,9	deleterious	3,22	22,7	0,46	0,55	NA	NA	neutral	0,38	neutral	0,41	neutral	0,17	7	neutral	0,22	deleterious	0,78	neutral	-3	deleterious	0,73	medium_impact	0,08	medium_impact	0,4	medium_impact	0,64	0,81	0,85	4,15	10,6	P	0,56	P	0,92	disease_causing	0,8	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12577	12577	A	C	MI.19742	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	241	81	K	Q	Aaa/Caa	-4,63	0	0	probably_damaging	1	neutral	0,3	neutral	1,46	neutral	-1,7	deleterious	-3,94	medium_impact	2,46	neutral	0,73	neutral	0,33	deleterious	3,3	22,9	0,49	0,55	disease	0,58	disease	0,68	disease	0,58	disease	0,52	0	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,03	medium_impact	1,04	0,61	0,8	28,86	7,16	N	0,28	N	0,82	polymorphism	0,87	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12577	12577	A	G	MI.19743	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	241	81	K	E	Aaa/Gaa	-4,63	0	0	probably_damaging	1	neutral	0,28	neutral	1,46	neutral	-1,6	deleterious	-3,94	medium_impact	3,42	neutral	0,69	damaging	0,26	deleterious	3,85	23,4	0,4	0,5	disease	0,55	disease	0,82	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,01	medium_impact	1,92	0,61	0,8	28,86	7,16	N	0,3	N	0,84	polymorphism	0,8	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12578	12578	A	T	MI.19744	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	242	81	K	M	aAa/aTa	8,44	1	0	probably_damaging	1	neutral	0,26	neutral	1,43	neutral	-2,71	deleterious	-5,91	medium_impact	2,72	neutral	0,73	neutral	0,29	deleterious	3,86	23,5	0,28	0,45	disease	0,87	disease	0,72	disease	0,59	disease	0,73	5	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	-0,02	medium_impact	1,28	0,41	0,8	28,86	7,16	P	0,52	P	0,4	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12578	12578	A	C	MI.19745	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	242	81	K	T	aAa/aCa	8,44	1	0	probably_damaging	1	neutral	0,41	neutral	1,5	neutral	-0,94	deleterious	-5,91	medium_impact	2,15	neutral	0,77	damaging	0,26	deleterious	3,53	23,1	0,24	0,45	disease	0,69	disease	0,68	disease	0,59	disease	0,55	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,15	medium_impact	0,76	0,46	0,8	28,86	7,16	N	0,46	N	0,75	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12579	12579	A	C	MI.19746	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	243	81	K	N	aaA/aaC	3,85	0,99	0	probably_damaging	1	neutral	0,37	neutral	1,44	neutral	-2,27	deleterious	-4,92	medium_impact	2,58	neutral	0,73	neutral	0,3	deleterious	3,65	23,2	0,58	0,65	neutral	0,43	disease	0,76	disease	0,58	disease	0,62	2	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,11	medium_impact	1,15	0,67	0,85	28,86	7,16	N	0,45	N	0,63	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12579	12579	A	T	MI.19747	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	243	81	K	N	aaA/aaT	3,85	0,99	0	probably_damaging	1	neutral	0,37	neutral	1,44	neutral	-2,27	deleterious	-4,92	medium_impact	2,58	neutral	0,73	neutral	0,3	deleterious	3,71	23,3	0,58	0,65	neutral	0,43	disease	0,76	disease	0,58	disease	0,62	2	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,11	medium_impact	1,15	0,67	0,85	28,86	7,16	N	0,46	N	0,63	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12580	12580	C	A	MI.19748	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	244	82	L	M	Cta/Ata	0,87	0,25	0	possibly_damaging	0,66	neutral	0,33	neutral	1,32	deleterious	-3,07	neutral	-1	low_impact	1,54	neutral	0,81	neutral	0,96	deleterious	2,35	18,49	0,25	0,45	neutral	0,31	neutral	0,24	neutral	0,28	neutral	0,44	1	neutral	0,73	neutral	0,34	neutral	-3	deleterious	0,68	low_impact	-1,02	medium_impact	0,06	medium_impact	0,2	0,91	0,95	19,57	15,46	N	0,41	N	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12580	12580	C	G	MI.19749	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	244	82	L	V	Cta/Gta	0,87	0,25	0	possibly_damaging	0,9	neutral	0,49	neutral	1,36	neutral	-0,25	neutral	-2,47	low_impact	1,92	neutral	0,81	neutral	0,38	deleterious	3,25	22,8	0,3	0,45	neutral	0,47	neutral	0,44	neutral	0,46	neutral	0,47	1	neutral	0,89	neutral	0,3	neutral	-3	deleterious	0,73	low_impact	-1,65	medium_impact	0,22	medium_impact	0,55	0,81	0,85	19,57	15,46	N	0,25	N	0,34	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5947	5947	T	A	MI.1975	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	44	15	I	N	aTt/aAt	7,07	1	0	probably_damaging	1	deleterious	0	neutral	-0,53	deleterious	-7,68	neutral	-1,47	high_impact	4,46	neutral	0,62	damaging	0,12	deleterious	4,22	23,9	0,22	0,55	disease	0,93	disease	0,91	disease	0,7	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,02	0,35	0,9	1,17	6,73	P	0,5	N	0,94	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12581	12581	T	G	MI.19750	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	245	82	L	R	cTa/cGa	-0,96	0	0	probably_damaging	0,99	neutral	0,33	neutral	1,25	deleterious	-4,71	deleterious	-5,18	high_impact	3,67	neutral	0,62	damaging	0,14	deleterious	4,1	23,7	0,1	0,4	disease	0,73	disease	0,88	disease	0,76	disease	0,82	6	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-2,64	medium_impact	0,06	high_impact	2,15	0,49	0,8	19,57	15,46	N	0,34	N	0,9	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12581	12581	T	A	MI.19751	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	245	82	L	Q	cTa/cAa	-0,96	0	0	probably_damaging	0,99	neutral	0,28	neutral	1,25	deleterious	-4,93	deleterious	-5,02	medium_impact	3,33	neutral	0,7	damaging	0,2	deleterious	4,26	23,9	0,13	0,4	disease	0,74	disease	0,66	disease	0,64	disease	0,72	4	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,83	low_impact	-2,64	medium_impact	0,01	medium_impact	1,84	0,71	0,85	19,57	15,46	N	0,3	N	0,87	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12581	12581	T	C	MI.19752	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	245	82	L	P	cTa/cCa	-0,96	0	0	probably_damaging	1	neutral	0,22	neutral	1,24	deleterious	-5,29	deleterious	-6,16	high_impact	3,67	damaging	0,54	damaging	0,12	deleterious	3,85	23,4	0,13	0,4	disease	0,81	disease	0,85	disease	0,64	disease	0,79	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,07	high_impact	2,15	0,66	0,8	19,57	15,46	N	0,27	N	0,95	disease_causing	0,52	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12583	12583	G	T	MI.19753	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	247	83	D	Y	Gac/Tac	-0,73	0,02	0	probably_damaging	1	neutral	1	neutral	-0,38	deleterious	-9,68	deleterious	-8,86	high_impact	4,06	damaging	0,35	neutral	0,31	deleterious	3,76	23,3	0,17	0,45	disease	0,89	disease	0,91	disease	0,88	disease	0,86	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,89	low_impact	-3,6	high_impact	1,89	high_impact	2,51	0,4	0,8	27,69	7,06	P	0,59	P	0,99	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12583	12583	G	A	MI.19754	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	247	83	D	N	Gac/Aac	-0,73	0,02	0	probably_damaging	1	neutral	0,35	neutral	-0,31	deleterious	-5,74	deleterious	-4,92	medium_impact	3,12	damaging	0,45	neutral	0,55	deleterious	4,05	23,7	0,44	0,55	neutral	0,23	disease	0,78	disease	0,86	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,08	medium_impact	1,65	0,76	0,85	27,69	7,06	N	0,51	P	0,98	disease_causing	0,98	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12583	12583	G	C	MI.19755	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	247	83	D	H	Gac/Cac	-0,73	0,02	0	probably_damaging	1	neutral	0,54	neutral	-0,38	deleterious	-8,48	deleterious	-6,89	high_impact	4,41	damaging	0,4	neutral	0,3	deleterious	3,47	23	0,21	0,45	disease	0,53	disease	0,85	disease	0,91	disease	0,8	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,27	high_impact	2,83	0,61	0,8	27,69	7,06	P	0,59	P	0,99	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12584	12584	A	G	MI.19756	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	248	83	D	G	gAc/gGc	9,13	1	0	probably_damaging	1	neutral	0,35	neutral	-0,36	deleterious	-7,35	deleterious	-6,89	high_impact	4,41	damaging	0,35	neutral	0,41	deleterious	3,75	23,3	0,21	0,45	disease	0,74	disease	0,85	disease	0,86	disease	0,8	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,08	high_impact	2,83	0,48	0,8	27,69	7,06	P	0,77	P	0,98	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12584	12584	A	T	MI.19757	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	248	83	D	V	gAc/gTc	9,13	1	0	probably_damaging	1	neutral	0,51	neutral	-0,38	deleterious	-9,14	deleterious	-8,86	high_impact	4,41	damaging	0,29	neutral	0,36	deleterious	3,52	23,1	0,17	0,45	disease	0,83	disease	0,91	disease	0,87	disease	0,83	7	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,24	high_impact	2,83	0,35	0,8	27,69	7,06	P	0,86	P	0,99	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12584	12584	A	C	MI.19758	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	248	83	D	A	gAc/gCc	9,13	1	0	probably_damaging	1	neutral	0,55	neutral	-0,36	deleterious	-7,37	deleterious	-7,88	high_impact	4,41	damaging	0,38	neutral	0,44	deleterious	3,45	23	0,18	0,45	disease	0,67	disease	0,78	disease	0,86	disease	0,8	6	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,28	high_impact	2,83	0,55	0,8	27,69	7,06	P	0,75	P	0,94	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12585	12585	C	G	MI.19759	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	249	83	D	E	gaC/gaG	6,61	1	0	probably_damaging	1	neutral	0,32	neutral	-0,31	deleterious	-5,71	deleterious	-3,94	high_impact	4,41	damaging	0,36	neutral	0,35	deleterious	3,78	23,4	0,29	0,45	disease	0,51	disease	0,75	disease	0,84	disease	0,79	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,05	high_impact	2,83	0,41	0,8	27,69	7,06	P	0,8	P	0,91	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5947	5947	T	G	MI.1976	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	44	15	I	S	aTt/aGt	7,07	1	0	probably_damaging	1	deleterious	0	neutral	-0,53	deleterious	-6,63	neutral	-1,26	high_impact	4,46	neutral	0,74	damaging	0,15	deleterious	4,12	23,8	0,24	0,55	disease	0,87	disease	0,89	disease	0,7	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,02	0,43	0,9	1,17	6,73	P	0,52	P	0,62	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12585	12585	C	A	MI.19760	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	249	83	D	E	gaC/gaA	6,61	1	0	probably_damaging	1	neutral	0,32	neutral	-0,31	deleterious	-5,71	deleterious	-3,94	high_impact	4,41	damaging	0,36	neutral	0,35	deleterious	3,98	23,6	0,29	0,45	disease	0,51	disease	0,75	disease	0,84	disease	0,79	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,05	high_impact	2,83	0,41	0,8	27,69	7,06	P	0,81	P	0,91	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12586	12586	T	G	MI.19761	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	250	84	Y	D	Tac/Gac	-2,8	0	0	probably_damaging	0,98	neutral	0,24	neutral	1,54	neutral	0,42	deleterious	-8,81	medium_impact	3,02	neutral	0,74	damaging	0,14	deleterious	3,84	23,4	0,38	0,5	disease	0,63	disease	0,73	disease	0,63	disease	0,71	4	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,79	low_impact	-2,35	medium_impact	-0,04	medium_impact	1,56	0,34	0,8	8,46	11,1	N	0,32	N	0,95	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12586	12586	T	A	MI.19762	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	250	84	Y	N	Tac/Aac	-2,8	0	0	probably_damaging	0,98	neutral	0,33	neutral	1,54	neutral	1,03	deleterious	-7,92	medium_impact	2,33	neutral	0,8	damaging	0,26	deleterious	4,07	23,7	0,42	0,55	disease	0,59	disease	0,59	disease	0,52	disease	0,54	1	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,75	low_impact	-2,35	medium_impact	0,06	medium_impact	0,93	0,29	0,8	8,46	11,1	N	0,27	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12586	12586	T	C	MI.19763	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	250	84	Y	H	Tac/Cac	-2,8	0	0	probably_damaging	0,98	neutral	0,54	neutral	1,55	neutral	-0,12	deleterious	-4,31	low_impact	0,92	neutral	0,81	neutral	0,85	neutral	1,71	14,49	0,61	0,65	disease	0,69	neutral	0,3	neutral	0,31	disease	0,62	2	deleterious	0,98	neutral	0,28	neutral	-2	deleterious	0,74	low_impact	-2,35	medium_impact	0,27	medium_impact	-0,36	0,41	0,8	8,46	11,1	N	0,27	N	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12587	12587	A	T	MI.19764	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	251	84	Y	F	tAc/tTc	-0,5	0	0	benign	0,12	neutral	0,7	neutral	1,53	neutral	-0,04	deleterious	-2,82	neutral_impact	0,5	neutral	0,79	neutral	0,93	neutral	1,76	14,75	0,49	0,55	disease	0,51	neutral	0,36	neutral	0,23	neutral	0,36	3	neutral	0,19	deleterious	0,79	neutral	-6	deleterious	0,72	medium_impact	0,08	medium_impact	0,44	medium_impact	-0,75	0,46	0,8	8,46	11,1	N	0,26	N	0,34	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12587	12587	A	C	MI.19765	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	251	84	Y	S	tAc/tCc	-0,5	0	0	probably_damaging	0,95	neutral	0,44	neutral	1,69	neutral	1,87	deleterious	-7,81	low_impact	1,7	neutral	0,78	neutral	0,47	deleterious	2,47	19,31	0,32	0,5	neutral	0,44	neutral	0,44	disease	0,52	neutral	0,48	0	neutral	0,95	neutral	0,25	neutral	-2	deleterious	0,72	low_impact	-1,96	medium_impact	0,18	medium_impact	0,35	0,23	0,8	8,46	11,1	N	0,33	N	0,91	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12587	12587	A	G	MI.19766	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	251	84	Y	C	tAc/tGc	-0,5	0	0	probably_damaging	0,99	neutral	0,18	neutral	1,5	neutral	-2,73	deleterious	-7,86	medium_impact	2,47	neutral	0,72	neutral	0,3	deleterious	3,42	23	0,32	0,5	disease	0,76	disease	0,71	neutral	0,38	disease	0,56	1	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,77	low_impact	-2,64	medium_impact	-0,13	medium_impact	1,05	0,15	0,8	8,46	11,1	N	0,35	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12589	12589	T	G	MI.19767	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	253	85	F	V	Ttc/Gtc	-5,32	0	0	possibly_damaging	0,73	neutral	0,53	neutral	1,66	neutral	-0,93	deleterious	-6,82	medium_impact	2,44	neutral	0,74	neutral	0,57	deleterious	4,02	23,6	0,33	0,5	neutral	0,41	disease	0,8	disease	0,69	disease	0,77	5	neutral	0,7	neutral	0,4	NA	0	deleterious	0,73	low_impact	-1,16	medium_impact	0,26	medium_impact	1,03	0,66	0,8	4,15	8,81	N	0,28	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12589	12589	T	A	MI.19768	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	253	85	F	I	Ttc/Atc	-5,32	0	0	possibly_damaging	0,73	neutral	0,38	neutral	1,6	neutral	0,04	deleterious	-5,84	medium_impact	2,23	neutral	0,73	neutral	0,58	deleterious	4,41	24,1	0,27	0,45	neutral	0,45	disease	0,75	disease	0,67	disease	0,7	4	neutral	0,75	neutral	0,33	NA	0	deleterious	0,75	low_impact	-1,16	medium_impact	0,12	medium_impact	0,83	0,64	0,8	4,15	8,81	N	0,3	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12589	12589	T	C	MI.19769	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	253	85	F	L	Ttc/Ctc	-5,32	0	0	benign	0,08	neutral	0,71	neutral	1,96	neutral	2,47	deleterious	-5,82	low_impact	1,22	neutral	0,78	neutral	0,72	deleterious	4	23,6	0,42	0,55	neutral	0,39	disease	0,55	disease	0,62	neutral	0,5	0	neutral	0,2	deleterious	0,82	neutral	-6	deleterious	0,7	medium_impact	0,26	medium_impact	0,45	medium_impact	-0,09	0,8	0,85	4,15	8,81	N	0,27	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5948	5948	T	A	MI.1977	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	45	15	I	M	atT/atA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	-0,51	deleterious	-5,27	neutral	-0,62	high_impact	4,46	neutral	0,7	damaging	0,15	deleterious	3,49	23,1	0,26	0,55	disease	0,73	disease	0,76	disease	0,55	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,02	0,82	0,9	1,17	6,73	P	0,52	P	0,76	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12590	12590	T	A	MI.19770	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	254	85	F	Y	tTc/tAc	4,54	0,99	0	benign	0,12	neutral	0,79	neutral	1,6	neutral	-1,51	deleterious	-2,94	neutral_impact	-0,46	neutral	0,71	neutral	0,77	neutral	1,71	14,45	0,3	0,45	neutral	0,37	neutral	0,13	neutral	0,27	neutral	0,21	6	neutral	0,1	deleterious	0,84	neutral	-6	deleterious	0,68	medium_impact	0,08	medium_impact	0,55	low_impact	-1,62	0,67	0,85	4,15	8,81	N	0,44	N	0,88	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12590	12590	T	G	MI.19771	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	254	85	F	C	tTc/tGc	4,54	0,99	0	probably_damaging	0,98	neutral	0,14	neutral	1,49	deleterious	-3,9	deleterious	-7,81	medium_impact	2,78	neutral	0,68	neutral	0,47	deleterious	3,95	23,6	0,23	0,45	disease	0,76	disease	0,82	disease	0,7	disease	0,78	6	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,8	low_impact	-2,35	medium_impact	-0,2	medium_impact	1,34	0,49	0,8	4,15	8,81	N	0,42	N	0,99	polymorphism	0,89	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12590	12590	T	C	MI.19772	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	254	85	F	S	tTc/tCc	4,54	0,99	0	probably_damaging	0,94	neutral	0,5	neutral	1,51	neutral	-2,4	deleterious	-7,82	medium_impact	2,58	neutral	0,69	neutral	0,49	deleterious	4,06	23,7	0,25	0,45	disease	0,51	disease	0,74	disease	0,67	disease	0,73	5	neutral	0,93	neutral	0,28	deleterious	1	deleterious	0,78	low_impact	-1,88	medium_impact	0,23	medium_impact	1,15	0,55	0,8	4,15	8,81	N	0,45	N	0,97	polymorphism	0,93	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12591	12591	C	G	MI.19773	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	255	85	F	L	ttC/ttG	3,17	0,99	0	benign	0,08	neutral	0,71	neutral	1,96	neutral	2,47	deleterious	-5,82	low_impact	1,22	neutral	0,78	neutral	0,72	deleterious	4,2	23,9	0,42	0,55	neutral	0,39	disease	0,55	disease	0,62	neutral	0,5	0	neutral	0,2	deleterious	0,82	neutral	-6	deleterious	0,7	medium_impact	0,26	medium_impact	0,45	medium_impact	-0,09	0,8	0,85	4,15	8,81	N	0,34	N	0,92	polymorphism	0,97	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12591	12591	C	A	MI.19774	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	255	85	F	L	ttC/ttA	3,17	0,99	0	benign	0,08	neutral	0,71	neutral	1,96	neutral	2,47	deleterious	-5,82	low_impact	1,22	neutral	0,78	neutral	0,72	deleterious	4,45	24,2	0,42	0,55	neutral	0,39	disease	0,55	disease	0,62	neutral	0,5	0	neutral	0,2	deleterious	0,82	neutral	-6	deleterious	0,7	medium_impact	0,26	medium_impact	0,45	medium_impact	-0,09	0,8	0,85	4,15	8,81	N	0,34	N	0,92	polymorphism	0,97	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12592	12592	T	G	MI.19775	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	256	86	S	A	Tcc/Gcc	-0,73	0,18	0	probably_damaging	1	neutral	0,69	neutral	1,27	neutral	-1,63	deleterious	-2,78	medium_impact	2,7	neutral	0,73	neutral	0,31	deleterious	3,43	23	0,29	0,45	neutral	0,41	disease	0,51	disease	0,52	neutral	0,45	1	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,7	low_impact	-3,6	medium_impact	0,42	medium_impact	1,26	0,86	0,9	4,31	7,84	N	0,22	N	0,49	polymorphism	0,94	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12592	12592	T	C	MI.19776	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	256	86	S	P	Tcc/Ccc	-0,73	0,18	0	probably_damaging	1	neutral	0,28	neutral	1,11	deleterious	-5,07	deleterious	-4,82	high_impact	3,7	neutral	0,72	damaging	0,14	deleterious	3,78	23,4	0,18	0,45	disease	0,87	disease	0,86	disease	0,83	disease	0,85	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,01	high_impact	2,18	0,75	0,85	4,31	7,84	N	0,43	N	0,98	disease_causing	0,59	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12592	12592	T	A	MI.19777	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	256	86	S	T	Tcc/Acc	-0,73	0,18	0	probably_damaging	1	neutral	0,55	neutral	1,53	neutral	-0,22	deleterious	-2,86	medium_impact	2,13	neutral	0,65	damaging	0,22	deleterious	3,55	23,1	0,23	0,45	disease	0,7	neutral	0,43	disease	0,63	disease	0,6	2	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,28	medium_impact	0,74	0,88	0,9	4,31	7,84	N	0,22	N	0,71	polymorphism	0,81	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12593	12593	C	A	MI.19778	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	257	86	S	Y	tCc/tAc	2,71	0,97	0	probably_damaging	1	neutral	1	neutral	1,11	deleterious	-5,37	deleterious	-5,76	high_impact	4,25	neutral	0,74	damaging	0,14	deleterious	3,92	23,5	0,16	0,45	disease	0,93	disease	0,86	disease	0,76	disease	0,85	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,86	low_impact	-3,6	high_impact	1,89	high_impact	2,68	0,81	0,85	4,31	7,84	N	0,43	N	0,99	disease_causing	0,99	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12593	12593	C	T	MI.19779	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	257	86	S	F	tCc/tTc	2,71	0,97	0	probably_damaging	1	neutral	0,79	neutral	1,19	neutral	-2,58	deleterious	-5,76	medium_impact	2,97	neutral	0,69	damaging	0,11	deleterious	4,1	23,7	0,15	0,4	disease	0,93	disease	0,88	disease	0,75	disease	0,84	7	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,55	medium_impact	1,51	0,45	0,8	4,31	7,84	N	0,32	N	0,99	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5948	5948	T	G	MI.1978	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	45	15	I	M	atT/atG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	-0,51	deleterious	-5,27	neutral	-0,62	high_impact	4,46	neutral	0,7	damaging	0,15	deleterious	3,25	22,8	0,26	0,55	disease	0,73	disease	0,76	disease	0,55	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,02	0,82	0,9	1,17	6,73	P	0,5	N	0,76	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12593	12593	C	G	MI.19780	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	257	86	S	C	tCc/tGc	2,71	0,97	0	probably_damaging	1	neutral	0,19	neutral	1,1	deleterious	-5,6	deleterious	-4,58	high_impact	3,9	neutral	0,71	damaging	0,16	deleterious	3,38	23	0,23	0,45	disease	0,92	disease	0,82	disease	0,66	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	-0,12	high_impact	2,36	0,65	0,8	4,31	7,84	N	0,44	N	0,99	disease_causing	0,99	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12595	12595	A	T	MI.19781	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	259	87	M	L	Ata/Tta	-6,47	0	0	benign	0,12	neutral	0,84	neutral	1,79	neutral	1,44	neutral	-0,34	neutral_impact	-0,24	neutral	0,84	neutral	0,97	neutral	-0,53	0,19	0,55	0,6	neutral	0,38	neutral	0,42	neutral	0,4	neutral	0,45	1	neutral	0,07	deleterious	0,86	neutral	-6	neutral	0,16	medium_impact	0,08	medium_impact	0,63	low_impact	-1,42	0,51	0,8	18,91	14,09	N	0,32	N	0,53	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12595	12595	A	C	MI.19782	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	259	87	M	L	Ata/Cta	-6,47	0	0	benign	0,12	neutral	0,84	neutral	1,79	neutral	1,44	neutral	-0,34	neutral_impact	-0,24	neutral	0,84	neutral	0,97	neutral	-0,66	0,09	0,55	0,6	neutral	0,38	neutral	0,42	neutral	0,4	neutral	0,45	1	neutral	0,07	deleterious	0,86	neutral	-6	neutral	0,16	medium_impact	0,08	medium_impact	0,63	low_impact	-1,42	0,51	0,8	18,91	14,09	N	0,31	N	0,53	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12595	12595	A	G	MI.19783	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	259	87	M	V	Ata/Gta	-6,47	0	0	benign	0,01	neutral	0,55	neutral	1,66	neutral	0,87	neutral	-1,05	low_impact	0,9	neutral	0,87	neutral	0,99	neutral	-0,5	0,22	0,61	0,65	neutral	0,21	neutral	0,47	neutral	0,44	neutral	0,44	1	neutral	0,43	deleterious	0,77	neutral	-6	neutral	0,12	medium_impact	1,15	medium_impact	0,28	medium_impact	-0,38	0,51	0,8	18,91	14,09	N	0,28	N	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12596	12596	T	A	MI.19784	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	260	87	M	K	aTa/aAa	-1,19	0	0	possibly_damaging	0,81	neutral	0,26	neutral	1,5	neutral	-1,87	deleterious	-4,38	medium_impact	2,83	neutral	0,75	neutral	0,48	deleterious	2,21	17,57	0,28	0,45	disease	0,73	disease	0,82	disease	0,7	disease	0,79	6	neutral	0,86	neutral	0,23	NA	0	deleterious	0,59	low_impact	-1,34	medium_impact	-0,02	medium_impact	1,38	0,6	0,8	18,91	14,09	N	0,3	N	0,93	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12596	12596	T	C	MI.19785	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	260	87	M	T	aTa/aCa	-1,19	0	0	possibly_damaging	0,48	neutral	0,43	neutral	1,56	neutral	-1,06	deleterious	-3,36	low_impact	1,19	neutral	0,86	neutral	0,98	neutral	-0,07	1,98	0,47	0,55	neutral	0,19	neutral	0,45	neutral	0,45	neutral	0,44	1	neutral	0,54	deleterious	0,48	neutral	-3	neutral	0,33	medium_impact	-0,71	medium_impact	0,17	medium_impact	-0,12	0,5	0,8	18,91	14,09	N	0,34	N	0,81	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12597	12597	A	T	MI.19786	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	261	87	M	I	atA/atT	2,94	0,12	0	benign	0,04	neutral	0,54	neutral	1,62	neutral	0,16	neutral	-0,69	neutral_impact	-0,64	neutral	0,83	neutral	0,97	neutral	-1,25	0,01	0,57	0,65	neutral	0,24	neutral	0,29	neutral	0,34	neutral	0,42	2	neutral	0,41	deleterious	0,75	neutral	-6	neutral	0,15	medium_impact	0,57	medium_impact	0,27	low_impact	-1,79	0,61	0,8	18,91	14,09	N	0,36	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12597	12597	A	C	MI.19787	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	261	87	M	I	atA/atC	2,94	0,12	0	benign	0,04	neutral	0,54	neutral	1,62	neutral	0,16	neutral	-0,69	neutral_impact	-0,64	neutral	0,83	neutral	0,97	neutral	-1,31	0	0,57	0,65	neutral	0,24	neutral	0,29	neutral	0,34	neutral	0,42	2	neutral	0,41	deleterious	0,75	neutral	-6	neutral	0,15	medium_impact	0,57	medium_impact	0,27	low_impact	-1,79	0,61	0,8	18,91	14,09	N	0,35	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12598	12598	A	C	MI.19788	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	262	88	M	L	Ata/Cta	-6,7	0	0	benign	0,01	neutral	0,73	neutral	1,64	neutral	1,81	neutral	0,03	neutral_impact	-0,13	neutral	0,86	neutral	0,97	neutral	-0,13	1,54	0,48	0,55	neutral	0,3	disease	0,54	neutral	0,47	neutral	0,46	1	neutral	0,25	deleterious	0,86	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,47	low_impact	-1,32	0,48	0,8	16,75	14,26	N	0,28	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12598	12598	A	T	MI.19789	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	262	88	M	L	Ata/Tta	-6,7	0	0	benign	0,01	neutral	0,73	neutral	1,64	neutral	1,81	neutral	0,03	neutral_impact	-0,13	neutral	0,86	neutral	0,97	deleterious	-0,06	2,07	0,48	0,55	neutral	0,3	disease	0,54	neutral	0,47	neutral	0,46	1	neutral	0,25	deleterious	0,86	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,47	low_impact	-1,32	0,48	0,8	16,75	14,26	N	0,29	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5949	5949	G	C	MI.1979	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	46	16	G	R	Gga/Cga	-4,27	0	0	probably_damaging	1	deleterious	0	neutral	2,7	deleterious	-6,46	neutral	-1,77	high_impact	4,84	neutral	0,7	damaging	0,09	deleterious	3,75	23,3	0,15	0,55	disease	0,87	disease	0,92	disease	0,77	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,6	0,9	4,09	7,65	P	0,7	P	0,95	disease_causing	0,97	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12598	12598	A	G	MI.19790	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	262	88	M	V	Ata/Gta	-6,7	0	0	benign	0,12	neutral	0,56	neutral	1,59	neutral	0,82	neutral	-0,39	neutral_impact	0,62	neutral	0,85	neutral	0,96	neutral	-0,52	0,19	0,57	0,65	neutral	0,4	disease	0,51	neutral	0,49	neutral	0,46	1	neutral	0,34	deleterious	0,72	neutral	-6	neutral	0,19	medium_impact	0,08	medium_impact	0,29	medium_impact	-0,64	0,5	0,8	16,75	14,26	N	0,27	N	0,22	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12599	12599	T	C	MI.19791	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	263	88	M	T	aTa/aCa	0,41	0	0	benign	0,01	neutral	0,42	neutral	1,6	neutral	0	neutral	-2,35	neutral_impact	0,3	neutral	0,85	neutral	0,99	neutral	-0,25	0,87	0,48	0,55	neutral	0,43	neutral	0,46	neutral	0,49	neutral	0,47	1	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,18	medium_impact	1,15	medium_impact	0,16	medium_impact	-0,93	0,39	0,8	16,75	14,26	N	0,34	N	0,03	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12599	12599	T	A	MI.19792	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	263	88	M	K	aTa/aAa	0,41	0	0	benign	0,26	neutral	0,3	neutral	1,47	neutral	-2,94	deleterious	-3,95	medium_impact	2,78	neutral	0,72	neutral	0,46	deleterious	2,16	17,27	0,23	0,45	disease	0,52	disease	0,85	disease	0,72	disease	0,8	6	neutral	0,64	deleterious	0,52	neutral	-3	neutral	0,41	medium_impact	-0,32	medium_impact	0,03	medium_impact	1,34	0,45	0,8	16,75	14,26	N	0,31	N	0,55	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12600	12600	A	C	MI.19793	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	264	88	M	I	atA/atC	1,1	0	0	benign	0,18	neutral	0,47	neutral	1,76	neutral	0,73	neutral	-0,06	neutral_impact	-0,58	neutral	0,84	neutral	0,98	neutral	-1,35	0	0,52	0,6	neutral	0,31	neutral	0,29	neutral	0,41	neutral	0,44	1	neutral	0,44	deleterious	0,65	neutral	-6	neutral	0,21	medium_impact	-0,12	medium_impact	0,2	low_impact	-1,73	0,62	0,8	16,75	14,26	N	0,34	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12600	12600	A	T	MI.19794	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	264	88	M	I	atA/atT	1,1	0	0	benign	0,18	neutral	0,47	neutral	1,76	neutral	0,73	neutral	-0,06	neutral_impact	-0,58	neutral	0,84	neutral	0,98	neutral	-1,29	0,01	0,52	0,6	neutral	0,31	neutral	0,29	neutral	0,41	neutral	0,44	1	neutral	0,44	deleterious	0,65	neutral	-6	neutral	0,21	medium_impact	-0,12	medium_impact	0,2	low_impact	-1,73	0,62	0,8	16,75	14,26	N	0,34	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12601	12601	T	C	MI.19795	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	265	89	F	L	Ttc/Ctc	-2,34	0	0	probably_damaging	1	neutral	0,74	neutral	1,2	neutral	-1,66	deleterious	-5,91	high_impact	3,86	damaging	0,5	neutral	0,5	deleterious	3,9	23,5	0,39	0,5	disease	0,71	disease	0,85	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,48	high_impact	2,32	0,78	0,85	27,53	7,08	N	0,38	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12601	12601	T	A	MI.19796	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	265	89	F	I	Ttc/Atc	-2,34	0	0	probably_damaging	1	neutral	0,56	neutral	1,05	deleterious	-3,22	deleterious	-5,91	high_impact	4,41	damaging	0,54	neutral	0,54	deleterious	4,24	23,9	0,23	0,45	disease	0,78	disease	0,91	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,29	high_impact	2,83	0,65	0,8	27,53	7,08	N	0,44	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12601	12601	T	G	MI.19797	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	265	89	F	V	Ttc/Gtc	-2,34	0	0	probably_damaging	1	neutral	0,71	neutral	1,08	neutral	-2,84	deleterious	-6,89	high_impact	4,06	damaging	0,55	neutral	0,48	deleterious	3,92	23,5	0,23	0,45	disease	0,74	disease	0,92	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,45	high_impact	2,51	0,59	0,8	27,53	7,08	N	0,33	N	0,95	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12602	12602	T	G	MI.19798	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	266	89	F	C	tTc/tGc	7,3	1	0	probably_damaging	1	neutral	0,17	neutral	0,98	deleterious	-6,79	deleterious	-7,88	high_impact	4,41	damaging	0,56	neutral	0,46	deleterious	3,93	23,5	0,19	0,45	disease	0,91	disease	0,91	disease	0,75	disease	0,84	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,15	high_impact	2,83	0,3	0,8	27,53	7,08	P	0,57	P	0,99	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12602	12602	T	A	MI.19799	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	266	89	F	Y	tTc/tAc	7,3	1	0	probably_damaging	1	neutral	1	neutral	0,99	deleterious	-5,34	deleterious	-2,95	high_impact	4,41	damaging	0,57	neutral	0,44	deleterious	4,22	23,9	0,22	0,45	disease	0,76	disease	0,85	disease	0,69	disease	0,73	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,81	low_impact	-3,6	high_impact	1,89	high_impact	2,83	0,68	0,85	27,53	7,08	P	0,58	P	0,88	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8619	8619	C	A	MI.198	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	93	31	I	M	atC/atA	0,59	0	0	benign	0,38	neutral	0,08	neutral	4,31	neutral	-1,22	neutral	-0,51	low_impact	1,11	neutral	0,94	neutral	0,77	neutral	0,97	10,49	0,57	0,65	disease	0,62	neutral	0,29	neutral	0,2	disease	0,56	1	neutral	0,91	neutral	0,35	neutral	-6	neutral	0,36	medium_impact	-0,55	medium_impact	-0,31	medium_impact	-0,15	0,4	0,9	28,32	22,32	N	0,47	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5949	5949	G	T	MI.1980	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	46	16	G	W	Gga/Tga	-4,27	0	0	probably_damaging	1	deleterious	0	neutral	2,69	deleterious	-9,44	neutral	-1,76	high_impact	4,49	neutral	0,69	damaging	0,11	deleterious	4,23	23,9	0,13	0,55	disease	0,97	disease	0,93	disease	0,73	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,05	0,34	0,9	4,09	7,65	N	0,43	N	0,83	disease_causing	0,98	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12602	12602	T	C	MI.19800	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	266	89	F	S	tTc/tCc	7,3	1	0	probably_damaging	1	neutral	0,54	neutral	0,98	deleterious	-5,9	deleterious	-7,88	high_impact	4,41	damaging	0,56	neutral	0,48	deleterious	4,16	23,8	0,19	0,45	disease	0,73	disease	0,89	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,27	high_impact	2,83	0,51	0,8	27,53	7,08	P	0,57	P	0,97	disease_causing	1	0,15	.	.	.	.	.	.	COSM1497296	.	.	.	.	.	.	.	.
chrM	12603	12603	C	A	MI.19801	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	267	89	F	L	ttC/ttA	7,3	1	0	probably_damaging	1	neutral	0,74	neutral	1,2	neutral	-1,66	deleterious	-5,91	high_impact	3,86	damaging	0,5	neutral	0,5	deleterious	4,51	24,3	0,39	0,5	disease	0,71	disease	0,85	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,48	high_impact	2,32	0,78	0,85	27,53	7,08	P	0,6	P	0,92	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12603	12603	C	G	MI.19802	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	267	89	F	L	ttC/ttG	7,3	1	0	probably_damaging	1	neutral	0,74	neutral	1,2	neutral	-1,66	deleterious	-5,91	high_impact	3,86	damaging	0,5	neutral	0,5	deleterious	4,17	23,8	0,39	0,5	disease	0,71	disease	0,85	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,48	high_impact	2,32	0,78	0,85	27,53	7,08	P	0,6	P	0,92	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12604	12604	A	G	MI.19803	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	268	90	I	V	Atc/Gtc	-3,49	0	0	benign	0,13	neutral	0,44	neutral	1,56	neutral	-0,27	neutral	-0,08	neutral_impact	0,73	neutral	0,85	neutral	0,97	neutral	-1,23	0,01	0,66	0,7	neutral	0,37	neutral	0,22	neutral	0,31	neutral	0,4	2	neutral	0,48	deleterious	0,66	neutral	-6	neutral	0,18	medium_impact	0,04	medium_impact	0,18	medium_impact	-0,54	0,48	0,8	23,38	17,09	N	0,39	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12604	12604	A	T	MI.19804	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	268	90	I	F	Atc/Ttc	-3,49	0	0	benign	0,37	neutral	0,86	neutral	1,5	neutral	-1,07	neutral	-2,35	low_impact	1,6	neutral	0,73	neutral	0,85	deleterious	1,93	15,75	0,39	0,5	neutral	0,47	disease	0,51	neutral	0,4	neutral	0,47	1	neutral	0,26	deleterious	0,75	neutral	-6	deleterious	0,5	medium_impact	-0,53	medium_impact	0,67	medium_impact	0,26	0,7	0,85	23,38	17,09	N	0,26	N	0,43	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12604	12604	A	C	MI.19805	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	268	90	I	L	Atc/Ctc	-3,49	0	0	benign	0,01	neutral	1	neutral	1,96	neutral	1,92	neutral	-0,41	neutral_impact	0,03	neutral	0,82	neutral	0,93	deleterious	0,03	2,83	0,36	0,5	neutral	0,36	neutral	0,24	neutral	0,3	neutral	0,45	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,11	medium_impact	1,15	high_impact	1,89	low_impact	-1,18	0,71	0,85	23,38	17,09	N	0,29	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12605	12605	T	G	MI.19806	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	269	90	I	S	aTc/aGc	-1,65	0	0	benign	0,27	neutral	0,35	neutral	1,51	neutral	-0,94	deleterious	-3,24	low_impact	1,7	neutral	0,8	neutral	0,67	deleterious	2,37	18,63	0,34	0,5	neutral	0,34	disease	0,63	neutral	0,5	neutral	0,48	0	neutral	0,58	deleterious	0,54	neutral	-6	neutral	0,41	medium_impact	-0,34	medium_impact	0,08	medium_impact	0,35	0,54	0,8	23,38	17,09	N	0,33	N	0,54	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12605	12605	T	A	MI.19807	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	269	90	I	N	aTc/aAc	-1,65	0	0	possibly_damaging	0,46	neutral	0,2	neutral	1,44	deleterious	-3,13	deleterious	-4,22	medium_impact	3,02	neutral	0,75	neutral	0,44	deleterious	4,01	23,6	0,3	0,45	disease	0,64	disease	0,72	disease	0,6	disease	0,71	4	neutral	0,77	neutral	0,37	NA	0	deleterious	0,64	medium_impact	-0,68	medium_impact	-0,1	medium_impact	1,56	0,51	0,8	23,38	17,09	N	0,33	N	0,7	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12605	12605	T	C	MI.19808	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	269	90	I	T	aTc/aCc	-1,65	0	0	benign	0,02	neutral	0,56	neutral	1,56	neutral	-0,24	neutral	-2,2	neutral_impact	0,16	neutral	0,88	neutral	0,96	neutral	-1,11	0,01	0,53	0,6	neutral	0,31	neutral	0,14	neutral	0,32	neutral	0,24	5	neutral	0,42	deleterious	0,77	neutral	-6	neutral	0,1	medium_impact	0,86	medium_impact	0,29	low_impact	-1,06	0,62	0,8	23,38	17,09	N	0,38	N	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12606	12606	C	A	MI.19809	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	270	90	I	M	atC/atA	0,87	0	0	benign	0,05	neutral	0,62	neutral	1,54	neutral	-0,55	neutral	0,43	neutral_impact	0,28	neutral	0,88	neutral	0,98	neutral	1,52	13,4	0,51	0,6	disease	0,6	neutral	0,19	neutral	0,3	neutral	0,47	1	neutral	0,31	deleterious	0,79	neutral	-6	deleterious	0,55	medium_impact	0,47	medium_impact	0,35	medium_impact	-0,95	0,76	0,85	23,38	17,09	N	0,33	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5950	5950	G	C	MI.1981	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	47	16	G	A	gGa/gCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,97	neutral	-2,1	neutral	-1,32	medium_impact	3,42	neutral	0,79	damaging	0,15	deleterious	2,88	21,8	0,25	0,55	neutral	0,28	disease	0,71	neutral	0,39	disease	0,53	1	deleterious	1	neutral	0	deleterious	5	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,06	0,64	0,9	4,09	7,65	N	0,46	N	0,64	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12606	12606	C	G	MI.19810	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	270	90	I	M	atC/atG	0,87	0	0	benign	0,05	neutral	0,62	neutral	1,54	neutral	-0,55	neutral	0,43	neutral_impact	0,28	neutral	0,88	neutral	0,98	neutral	1,07	11,08	0,51	0,6	disease	0,6	neutral	0,19	neutral	0,3	neutral	0,47	1	neutral	0,31	deleterious	0,79	neutral	-6	deleterious	0,55	medium_impact	0,47	medium_impact	0,35	medium_impact	-0,95	0,76	0,85	23,38	17,09	N	0,33	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12607	12607	C	T	MI.19811	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	271	91	P	S	Cct/Tct	-5,55	0	0	probably_damaging	1	neutral	0,4	neutral	1,66	neutral	0,81	deleterious	-5,89	low_impact	1,5	neutral	0,72	neutral	0,81	deleterious	2,62	20,3	0,42	0,55	neutral	0,41	disease	0,8	neutral	0,44	disease	0,52	0	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	0,14	medium_impact	0,17	0,3	0,8	7,13	11,76	N	0,31	N	0,31	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12607	12607	C	G	MI.19812	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	271	91	P	A	Cct/Gct	-5,55	0	0	probably_damaging	1	neutral	0,51	neutral	1,55	neutral	-0,62	deleterious	-6,35	medium_impact	3,35	neutral	0,66	damaging	0,16	deleterious	2,9	21,9	0,29	0,45	neutral	0,48	disease	0,76	disease	0,6	disease	0,62	2	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,24	medium_impact	1,86	0,77	0,85	7,13	11,76	N	0,24	N	0,64	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12607	12607	C	A	MI.19813	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	271	91	P	T	Cct/Act	-5,55	0	0	probably_damaging	1	neutral	0,39	neutral	1,53	neutral	-0,97	deleterious	-6,35	medium_impact	2,87	neutral	0,69	damaging	0,21	deleterious	3,52	23,1	0,33	0,5	neutral	0,28	disease	0,82	disease	0,55	disease	0,64	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,13	medium_impact	1,42	0,77	0,85	7,13	11,76	N	0,26	N	0,67	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12608	12608	C	A	MI.19814	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	272	91	P	H	cCt/cAt	0,41	0,01	0	probably_damaging	1	neutral	0,54	neutral	1,49	neutral	-2,83	deleterious	-7,49	high_impact	4,16	neutral	0,68	damaging	0,13	deleterious	3,8	23,4	0,25	0,45	disease	0,77	disease	0,9	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,27	high_impact	2,6	0,71	0,85	7,13	11,76	N	0,31	N	0,9	disease_causing	0,63	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12608	12608	C	G	MI.19815	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	272	91	P	R	cCt/cGt	0,41	0,01	0	probably_damaging	1	neutral	0,35	neutral	1,5	neutral	-2,25	deleterious	-7,49	high_impact	4,16	neutral	0,69	damaging	0,14	deleterious	3,44	23	0,22	0,45	disease	0,69	disease	0,95	disease	0,73	disease	0,87	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,08	high_impact	2,6	0,74	0,85	7,13	11,76	N	0,38	N	0,95	disease_causing	0,76	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12608	12608	C	T	MI.19816	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	272	91	P	L	cCt/cTt	0,41	0,01	0	probably_damaging	1	neutral	0,65	neutral	1,67	neutral	0,85	deleterious	-8,47	medium_impact	2,74	neutral	0,64	damaging	0,12	deleterious	4,15	23,8	0,35	0,5	neutral	0,35	disease	0,91	disease	0,62	disease	0,69	4	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,38	medium_impact	1,3	0,83	0,85	7,13	11,76	N	0,26	N	0,97	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12610	12610	G	T	MI.19817	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	274	92	V	L	Gta/Tta	-16,1	0	0	benign	0,4	neutral	0,84	neutral	1,27	neutral	0,41	deleterious	-2,66	medium_impact	2,69	neutral	0,69	neutral	0,54	neutral	1,72	14,51	0,41	0,5	neutral	0,46	disease	0,81	disease	0,55	disease	0,67	3	neutral	0,29	deleterious	0,72	neutral	-3	neutral	0,28	medium_impact	-0,58	medium_impact	0,63	medium_impact	1,25	0,65	0,8	13,76	12,87	N	0,24	N	0,51	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12610	12610	G	A	MI.19818	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	274	92	V	M	Gta/Ata	-16,1	0	0	probably_damaging	0,93	neutral	0,29	neutral	1,05	neutral	-2,69	deleterious	-2,77	medium_impact	2,87	neutral	0,78	neutral	0,59	deleterious	3,46	23	0,37	0,5	disease	0,67	disease	0,75	disease	0,61	disease	0,7	4	neutral	0,94	neutral	0,18	deleterious	1	deleterious	0,69	low_impact	-1,81	medium_impact	0,02	medium_impact	1,42	0,76	0,85	13,76	12,87	N	0,26	N	0,44	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12610	12610	G	C	MI.19819	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	274	92	V	L	Gta/Cta	-16,1	0	0	benign	0,4	neutral	0,84	neutral	1,27	neutral	0,41	deleterious	-2,66	medium_impact	2,69	neutral	0,69	neutral	0,54	neutral	1,63	14	0,41	0,5	neutral	0,46	disease	0,81	disease	0,55	disease	0,67	3	neutral	0,29	deleterious	0,72	neutral	-3	neutral	0,28	medium_impact	-0,58	medium_impact	0,63	medium_impact	1,25	0,65	0,8	13,76	12,87	N	0,24	N	0,51	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5950	5950	G	A	MI.1982	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	47	16	G	E	gGa/gAa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,7	deleterious	-5,92	neutral	-1,76	high_impact	4,84	neutral	0,66	damaging	0,1	deleterious	3,71	23,3	0,17	0,55	disease	0,83	disease	0,9	disease	0,76	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,52	0,9	4,09	7,65	P	0,73	P	0,93	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12611	12611	T	C	MI.19820	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	275	92	V	A	gTa/gCa	-0,04	0	0	possibly_damaging	0,53	neutral	0,2	neutral	1,07	neutral	-2,71	deleterious	-3,8	medium_impact	2,69	neutral	0,68	neutral	0,63	neutral	1,73	14,59	0,27	0,45	neutral	0,27	disease	0,71	disease	0,6	disease	0,66	3	neutral	0,79	neutral	0,34	NA	0	neutral	0,37	medium_impact	-0,8	medium_impact	-0,1	medium_impact	1,25	0,45	0,8	13,76	12,87	N	0,4	N	0,8	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12611	12611	T	A	MI.19821	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	275	92	V	E	gTa/gAa	-0,04	0	0	possibly_damaging	0,88	neutral	0,13	neutral	1,03	deleterious	-5,27	deleterious	-5,73	high_impact	3,85	neutral	0,63	neutral	0,46	deleterious	4,24	23,9	0,11	0,4	disease	0,71	disease	0,92	disease	0,72	disease	0,8	6	neutral	0,95	neutral	0,13	deleterious	1	deleterious	0,76	low_impact	-1,57	medium_impact	-0,22	high_impact	2,31	0,56	0,8	13,76	12,87	N	0,37	N	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12611	12611	T	G	MI.19822	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	275	92	V	G	gTa/gGa	-0,04	0	0	possibly_damaging	0,82	neutral	0,1	neutral	1,03	deleterious	-4,8	deleterious	-6,71	high_impact	3,85	neutral	0,64	neutral	0,56	deleterious	3,39	23	0,16	0,45	disease	0,76	disease	0,87	disease	0,62	disease	0,73	5	neutral	0,94	neutral	0,14	deleterious	1	deleterious	0,65	low_impact	-1,37	medium_impact	-0,29	high_impact	2,31	0,56	0,8	13,76	12,87	N	0,39	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12613	12613	G	T	MI.19823	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	277	93	A	S	Gca/Tca	-2,11	0	0	probably_damaging	1	neutral	0,44	neutral	1,4	neutral	-2,05	deleterious	-2,94	high_impact	3,64	neutral	0,7	neutral	0,68	deleterious	3,51	23,1	0,35	0,5	disease	0,55	disease	0,79	disease	0,59	disease	0,64	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,18	high_impact	2,12	0,77	0,85	23,88	7,03	N	0,33	N	0,98	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12613	12613	G	C	MI.19824	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	277	93	A	P	Gca/Cca	-2,11	0	0	probably_damaging	1	neutral	0,23	neutral	1,35	deleterious	-4,13	deleterious	-4,92	high_impact	4,34	neutral	0,68	neutral	0,34	deleterious	3,65	23,2	0,15	0,45	disease	0,8	disease	0,87	disease	0,76	disease	0,83	7	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,06	high_impact	2,76	0,68	0,85	23,88	7,03	N	0,48	N	0,96	polymorphism	0,99	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12613	12613	G	A	MI.19825	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	277	93	A	T	Gca/Aca	-2,11	0	0	probably_damaging	1	neutral	0,27	neutral	1,44	neutral	-1,31	deleterious	-3,93	high_impact	3,79	neutral	0,65	neutral	0,47	deleterious	4,05	23,7	0,4	0,5	disease	0,61	disease	0,79	disease	0,65	disease	0,64	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,01	high_impact	2,26	0,73	0,85	23,88	7,03	N	0,38	N	0,94	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12614	12614	C	G	MI.19826	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	278	93	A	G	gCa/gGa	5,92	1	0	probably_damaging	1	neutral	0,12	neutral	1,39	neutral	-2,36	deleterious	-3,93	medium_impact	3,24	neutral	0,67	neutral	0,52	deleterious	3,73	23,3	0,25	0,45	neutral	0,29	disease	0,78	disease	0,59	disease	0,63	3	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	-0,25	medium_impact	1,76	0,75	0,85	23,88	7,03	P	0,54	P	0,82	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12614	12614	C	A	MI.19827	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	278	93	A	E	gCa/gAa	5,92	1	0	probably_damaging	1	neutral	0,1	neutral	1,36	deleterious	-3,53	deleterious	-4,92	high_impact	4,34	neutral	0,66	neutral	0,41	deleterious	4,41	24,1	0,16	0,45	disease	0,6	disease	0,89	disease	0,74	disease	0,8	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,29	high_impact	2,76	0,59	0,8	23,88	7,03	P	0,63	P	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12614	12614	C	T	MI.19828	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	278	93	A	V	gCa/gTa	5,92	1	0	probably_damaging	1	neutral	0,74	neutral	2	neutral	1,62	deleterious	-3,94	medium_impact	2,73	neutral	0,65	neutral	0,58	deleterious	4,25	23,9	0,35	0,5	disease	0,65	disease	0,75	disease	0,66	disease	0,57	1	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,48	medium_impact	1,29	0,71	0,85	23,88	7,03	P	0,52	P	0,76	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12616	12616	T	G	MI.19829	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	280	94	L	V	Ttg/Gtg	-6,93	0	0,01	probably_damaging	1	neutral	0,36	neutral	1,06	deleterious	-3,58	deleterious	-2,95	high_impact	4,34	damaging	0,51	damaging	0,07	deleterious	3,26	22,8	0,44	0,55	disease	0,66	disease	0,69	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,1	high_impact	2,76	0,57	0,8	19,9	7,45	N	0,35	N	0,81	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5950	5950	G	T	MI.1983	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	47	16	G	V	gGa/gTa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,93	deleterious	-5,61	neutral	-1,99	high_impact	4,84	damaging	0,55	damaging	0,11	deleterious	3,59	23,2	0,14	0,55	disease	0,78	disease	0,89	disease	0,68	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,34	0,9	4,09	7,65	P	0,7	P	0,93	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12616	12616	T	A	MI.19830	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	280	94	L	M	Ttg/Atg	-6,93	0	0,01	probably_damaging	1	neutral	0,23	neutral	1,02	deleterious	-4,95	neutral	-1,97	high_impact	3,54	damaging	0,55	damaging	0,14	deleterious	3,41	23	0,37	0,5	disease	0,77	disease	0,54	disease	0,59	disease	0,57	1	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,74	low_impact	-3,6	medium_impact	-0,06	high_impact	2,03	0,66	0,8	19,9	7,45	N	0,32	N	0,89	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12617	12617	T	C	MI.19831	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	281	94	L	S	tTg/tCg	-0,04	0	0	probably_damaging	1	neutral	0,24	neutral	1,13	neutral	-2,38	deleterious	-5,91	medium_impact	3,31	damaging	0,49	damaging	0,08	deleterious	3,58	23,2	0,32	0,5	neutral	0,32	disease	0,76	disease	0,65	disease	0,62	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	-0,04	medium_impact	1,82	0,56	0,8	19,9	7,45	N	0,29	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12617	12617	T	G	MI.19832	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	281	94	L	W	tTg/tGg	-0,04	0	0	probably_damaging	1	neutral	0,06	neutral	1	deleterious	-7,11	deleterious	-5,91	high_impact	4	damaging	0,56	damaging	0,07	deleterious	3,56	23,1	0,15	0,4	disease	0,91	disease	0,77	disease	0,69	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,43	high_impact	2,45	0,55	0,8	19,9	7,45	N	0,31	N	0,98	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12618	12618	G	C	MI.19833	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	282	94	L	F	ttG/ttC	7,3	0,95	0,01	probably_damaging	1	neutral	0,75	neutral	1,02	deleterious	-4,97	deleterious	-3,94	medium_impact	3,1	damaging	0,51	damaging	0,08	deleterious	3,27	22,8	0,48	0,55	neutral	0,2	disease	0,73	disease	0,61	disease	0,61	2	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,71	low_impact	-3,6	medium_impact	0,5	medium_impact	1,63	0,71	0,85	19,9	7,45	N	0,38	N	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12618	12618	G	T	MI.19834	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	282	94	L	F	ttG/ttT	7,3	0,95	0,01	probably_damaging	1	neutral	0,75	neutral	1,02	deleterious	-4,97	deleterious	-3,94	medium_impact	3,1	damaging	0,51	damaging	0,08	deleterious	3,42	23	0,48	0,55	neutral	0,2	disease	0,73	disease	0,61	disease	0,61	2	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,71	low_impact	-3,6	medium_impact	0,5	medium_impact	1,63	0,71	0,85	19,9	7,45	N	0,38	N	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12619	12619	T	G	MI.19835	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	283	95	F	V	Ttc/Gtc	-1,65	0	0	possibly_damaging	0,74	neutral	0,74	neutral	1,52	neutral	-1,28	deleterious	-6,64	medium_impact	2,9	neutral	0,78	neutral	0,48	deleterious	2,21	17,54	0,32	0,5	neutral	0,43	disease	0,87	disease	0,65	disease	0,7	4	neutral	0,69	deleterious	0,5	NA	0	deleterious	0,46	low_impact	-1,18	medium_impact	0,48	medium_impact	1,45	0,41	0,8	15,42	13,52	N	0,22	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12619	12619	T	A	MI.19836	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	283	95	F	I	Ttc/Atc	-1,65	0	0	possibly_damaging	0,74	neutral	0,54	neutral	1,65	neutral	-1,03	deleterious	-5,68	medium_impact	2,75	neutral	0,79	neutral	0,52	deleterious	2,51	19,53	0,33	0,5	neutral	0,49	disease	0,87	disease	0,64	disease	0,57	1	neutral	0,71	neutral	0,4	NA	0	deleterious	0,49	low_impact	-1,18	medium_impact	0,27	medium_impact	1,31	0,49	0,8	15,42	13,52	N	0,21	N	0,77	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12619	12619	T	C	MI.19837	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	283	95	F	L	Ttc/Ctc	-1,65	0	0	benign	0,08	neutral	1	neutral	1,61	neutral	-0,31	deleterious	-5,64	low_impact	1,7	neutral	0,83	neutral	0,74	deleterious	0,8	9,46	0,44	0,55	neutral	0,23	disease	0,75	disease	0,56	disease	0,52	0	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,13	medium_impact	0,26	high_impact	1,89	medium_impact	0,35	0,54	0,8	15,42	13,52	N	0,24	N	0,31	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12620	12620	T	C	MI.19838	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	284	95	F	S	tTc/tCc	2,94	0,23	0	probably_damaging	0,96	neutral	0,63	neutral	1,51	neutral	-2,38	deleterious	-7,67	medium_impact	3,4	neutral	0,94	neutral	0,6	deleterious	3,9	23,5	0,3	0,45	disease	0,66	disease	0,8	disease	0,64	disease	0,57	1	neutral	0,95	neutral	0,34	deleterious	1	deleterious	0,67	low_impact	-2,06	medium_impact	0,36	medium_impact	1,9	0,29	0,8	15,42	13,52	N	0,33	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12620	12620	T	A	MI.19839	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	284	95	F	Y	tTc/tAc	2,94	0,23	0	possibly_damaging	0,89	neutral	0,65	neutral	1,47	deleterious	-3,07	deleterious	-2,74	low_impact	0,9	neutral	0,8	neutral	0,89	neutral	1,09	11,17	0,31	0,45	disease	0,65	neutral	0,29	neutral	0,41	disease	0,58	2	neutral	0,87	neutral	0,38	neutral	-3	deleterious	0,6	low_impact	-1,61	medium_impact	0,38	medium_impact	-0,38	0,53	0,8	15,42	13,52	N	0,31	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5952	5952	A	C	MI.1984	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	49	17	T	P	Aca/Cca	-3,58	0	0	probably_damaging	1	deleterious	0	neutral	2,74	deleterious	-4,93	neutral	-2,19	high_impact	4,47	damaging	0,54	damaging	0,09	deleterious	3,36	22,9	0,11	0,55	disease	0,71	disease	0,89	disease	0,7	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,03	0,62	0,9	3,51	6,79	N	0,4	N	0,92	disease_causing	0,85	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12620	12620	T	G	MI.19840	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	284	95	F	C	tTc/tGc	2,94	0,23	0	probably_damaging	0,98	neutral	0,11	neutral	1,43	deleterious	-4,23	deleterious	-7,65	medium_impact	3,4	neutral	0,71	neutral	0,44	deleterious	3,89	23,5	0,22	0,45	disease	0,67	disease	0,89	disease	0,68	disease	0,76	5	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,75	low_impact	-2,35	medium_impact	-0,27	medium_impact	1,9	0,22	0,8	15,42	13,52	N	0,4	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12621	12621	C	A	MI.19841	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	285	95	F	L	ttC/ttA	0,64	0,13	0	benign	0,08	neutral	1	neutral	1,61	neutral	-0,31	deleterious	-5,64	low_impact	1,7	neutral	0,83	neutral	0,74	neutral	1,5	13,34	0,44	0,55	neutral	0,23	disease	0,75	disease	0,56	disease	0,52	0	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,13	medium_impact	0,26	high_impact	1,89	medium_impact	0,35	0,54	0,8	15,42	13,52	N	0,26	N	0,31	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12621	12621	C	G	MI.19842	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	285	95	F	L	ttC/ttG	0,64	0,13	0	benign	0,08	neutral	1	neutral	1,61	neutral	-0,31	deleterious	-5,64	low_impact	1,7	neutral	0,83	neutral	0,74	neutral	1,15	11,47	0,44	0,55	neutral	0,23	disease	0,75	disease	0,56	disease	0,52	0	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,13	medium_impact	0,26	high_impact	1,89	medium_impact	0,35	0,54	0,8	15,42	13,52	N	0,27	N	0,31	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12622	12622	G	T	MI.19843	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	286	96	V	F	Gtt/Ttt	-3,94	0	0	possibly_damaging	0,88	neutral	0,93	neutral	0,52	deleterious	-6,82	deleterious	-4,73	high_impact	4,22	damaging	0,52	neutral	0,45	deleterious	3,56	23,1	0,16	0,45	disease	0,89	disease	0,9	disease	0,71	disease	0,82	6	neutral	0,87	deleterious	0,53	deleterious	1	deleterious	0,79	low_impact	-1,57	medium_impact	0,85	high_impact	2,65	0,7	0,85	9,29	13,35	N	0,37	N	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12622	12622	G	C	MI.19844	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	286	96	V	L	Gtt/Ctt	-3,94	0	0	benign	0,4	neutral	1	neutral	0,58	deleterious	-4,38	deleterious	-2,76	high_impact	4,22	damaging	0,51	neutral	0,52	neutral	1,62	13,96	0,33	0,5	disease	0,65	disease	0,76	disease	0,63	disease	0,65	3	neutral	0,4	deleterious	0,8	neutral	-2	neutral	0,37	medium_impact	-0,58	high_impact	1,89	high_impact	2,65	0,66	0,8	9,29	13,35	N	0,35	N	0,62	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12622	12622	G	A	MI.19845	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	286	96	V	I	Gtt/Att	-3,94	0	0	benign	0,03	neutral	0,55	neutral	1,07	neutral	-1,21	neutral	-0,79	low_impact	1,4	neutral	0,75	neutral	0,91	deleterious	0,3	5,66	0,45	0,55	neutral	0,38	neutral	0,47	neutral	0,47	neutral	0,42	2	neutral	0,42	deleterious	0,76	neutral	-6	neutral	0,17	medium_impact	0,69	medium_impact	0,28	medium_impact	0,08	0,86	0,9	9,29	13,35	N	0,36	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	G12622A	Leigh Disease	+	+	Significance unclear	1
chrM	12623	12623	T	C	MI.19846	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	287	96	V	A	gTt/gCt	1,1	0,76	0	possibly_damaging	0,53	neutral	0,57	neutral	0,53	deleterious	-5,86	deleterious	-3,94	high_impact	4,22	damaging	0,52	neutral	0,58	deleterious	3,02	22,3	0,29	0,45	disease	0,82	disease	0,65	disease	0,67	disease	0,7	4	neutral	0,48	deleterious	0,52	deleterious	1	deleterious	0,6	medium_impact	-0,8	medium_impact	0,3	high_impact	2,65	0,45	0,8	9,29	13,35	N	0,4	N	0,71	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12623	12623	T	A	MI.19847	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	287	96	V	D	gTt/gAt	1,1	0,76	0	probably_damaging	0,93	neutral	0,18	neutral	0,51	deleterious	-9,01	deleterious	-6,8	high_impact	4,22	damaging	0,55	neutral	0,44	deleterious	4,25	23,9	0,1	0,4	disease	0,97	disease	0,88	disease	0,79	disease	0,86	7	neutral	0,96	neutral	0,13	deleterious	2	deleterious	0,82	low_impact	-1,81	medium_impact	-0,13	high_impact	2,65	0,54	0,8	9,29	13,35	N	0,46	N	0,65	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12623	12623	T	G	MI.19848	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	287	96	V	G	gTt/gGt	1,1	0,76	0	possibly_damaging	0,86	neutral	0,32	neutral	0,51	deleterious	-8,39	deleterious	-6,9	high_impact	4,22	damaging	0,52	neutral	0,57	deleterious	3,59	23,2	0,16	0,45	disease	0,95	disease	0,82	disease	0,7	disease	0,83	7	neutral	0,88	neutral	0,23	deleterious	1	deleterious	0,78	low_impact	-1,5	medium_impact	0,05	high_impact	2,65	0,54	0,8	9,29	13,35	N	0,38	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12625	12625	A	G	MI.19849	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	289	97	T	A	Aca/Gca	-11,28	0	0	probably_damaging	1	neutral	0,61	neutral	1,39	neutral	-1,38	deleterious	-4,93	medium_impact	3,23	damaging	0,58	damaging	0,15	deleterious	3,32	22,9	0,61	0,65	disease	0,65	disease	0,68	disease	0,63	disease	0,6	2	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,34	medium_impact	1,75	0,43	0,8	21,89	7,34	N	0,22	N	0,7	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5952	5952	A	T	MI.1985	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	49	17	T	S	Aca/Tca	-3,58	0	0	probably_damaging	0,99	deleterious	0,03	neutral	2,78	neutral	-1,91	neutral	-1,44	medium_impact	2,4	neutral	0,69	damaging	0,12	deleterious	3,14	22,6	0,36	0,55	neutral	0,48	disease	0,69	neutral	0,32	disease	0,51	0	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,76	low_impact	-2,64	medium_impact	-0,65	medium_impact	1,12	0,68	0,9	3,51	6,79	N	0,3	N	0,79	polymorphism	0,73	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12625	12625	A	T	MI.19850	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	289	97	T	S	Aca/Tca	-11,28	0	0	probably_damaging	1	neutral	0,65	neutral	1,8	neutral	0,83	deleterious	-3,94	low_impact	1,88	neutral	0,6	damaging	0,2	deleterious	3,06	22,4	0,52	0,6	disease	0,69	neutral	0,4	disease	0,51	disease	0,59	2	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,38	medium_impact	0,51	0,75	0,85	21,89	7,34	N	0,25	N	0,69	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12625	12625	A	C	MI.19851	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	289	97	T	P	Aca/Cca	-11,28	0	0	probably_damaging	1	neutral	0,22	neutral	1,28	deleterious	-4,34	deleterious	-5,91	high_impact	4,28	neutral	0,63	damaging	0,07	deleterious	3,33	22,9	0,13	0,4	disease	0,86	disease	0,85	disease	0,79	disease	0,85	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	-0,07	high_impact	2,71	0,58	0,8	21,89	7,34	N	0,41	N	0,99	polymorphism	0,98	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12626	12626	C	T	MI.19852	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	290	97	T	M	aCa/aTa	2,71	0,76	0	probably_damaging	1	neutral	0,4	neutral	1,27	deleterious	-4,52	deleterious	-5,91	high_impact	4,28	neutral	0,62	damaging	0,07	deleterious	3,82	23,4	0,36	0,5	disease	0,78	disease	0,77	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,74	low_impact	-3,6	medium_impact	0,14	high_impact	2,71	0,75	0,85	21,89	7,34	N	0,36	N	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12626	12626	C	A	MI.19853	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	290	97	T	K	aCa/aAa	2,71	0,76	0	probably_damaging	1	neutral	0,27	neutral	1,3	deleterious	-3,21	deleterious	-5,91	high_impact	4,28	neutral	0,62	damaging	0,06	deleterious	4,24	23,9	0,19	0,45	disease	0,66	disease	0,88	disease	0,78	disease	0,81	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	-0,01	high_impact	2,71	0,69	0,85	21,89	7,34	N	0,49	N	0,98	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12628	12628	T	C	MI.19854	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	292	98	W	R	Tgg/Cgg	-6,93	0	0	probably_damaging	1	neutral	0,31	neutral	1,42	deleterious	-3	deleterious	-13,79	high_impact	3,77	neutral	0,61	damaging	0,15	deleterious	3,41	23	0,35	0,5	disease	0,73	disease	0,94	disease	0,79	disease	0,87	7	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,04	high_impact	2,24	0,36	0,8	29,19	7,32	N	0,45	N	0,97	polymorphism	0,86	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12628	12628	T	G	MI.19855	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	292	98	W	G	Tgg/Ggg	-6,93	0	0	probably_damaging	1	neutral	0,35	neutral	1,41	deleterious	-3,13	deleterious	-12,81	high_impact	3,52	neutral	0,62	damaging	0,18	deleterious	3,76	23,3	0,35	0,5	disease	0,74	disease	0,88	disease	0,77	disease	0,8	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,08	high_impact	2,01	0,33	0,8	29,19	7,32	N	0,4	N	0,97	polymorphism	0,7	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12629	12629	G	T	MI.19856	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	293	98	W	L	tGg/tTg	4,54	1	0	probably_damaging	1	neutral	1	neutral	1,55	neutral	-0,27	deleterious	-12,81	medium_impact	3,43	neutral	0,64	damaging	0,12	deleterious	4,08	23,7	0,24	0,45	neutral	0,36	disease	0,88	disease	0,76	disease	0,74	5	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,76	low_impact	-3,6	high_impact	1,89	medium_impact	1,93	0,32	0,8	29,19	7,32	N	0,39	N	0,97	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12629	12629	G	C	MI.19857	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	293	98	W	S	tGg/tCg	4,54	1	0	probably_damaging	1	neutral	0,64	neutral	1,62	neutral	0,29	deleterious	-13,79	medium_impact	2,98	damaging	0,59	damaging	0,15	deleterious	3,86	23,4	0,28	0,45	neutral	0,41	disease	0,88	disease	0,75	disease	0,64	3	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,37	medium_impact	1,52	0,33	0,8	29,19	7,32	N	0,38	N	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12630	12630	G	C	MI.19858	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	294	98	W	C	tgG/tgC	7,3	1	0,03	probably_damaging	1	neutral	0,16	neutral	1,41	deleterious	-3,53	deleterious	-12,81	high_impact	4,33	neutral	0,64	damaging	0,11	deleterious	3,85	23,4	0,33	0,5	disease	0,66	disease	0,92	disease	0,78	disease	0,82	6	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	-0,17	high_impact	2,75	0,29	0,8	29,19	7,32	P	0,54	P	0,98	disease_causing	1	0,06	.	.	.	.	.	.	COSM488732	.	.	.	.	.	.	.	.
chrM	12630	12630	G	T	MI.19859	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	294	98	W	C	tgG/tgT	7,3	1	0,03	probably_damaging	1	neutral	0,16	neutral	1,41	deleterious	-3,53	deleterious	-12,81	high_impact	4,33	neutral	0,64	damaging	0,11	deleterious	3,97	23,6	0,33	0,5	disease	0,66	disease	0,92	disease	0,78	disease	0,82	6	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	-0,17	high_impact	2,75	0,29	0,8	29,19	7,32	P	0,54	P	0,98	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5952	5952	A	G	MI.1986	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	49	17	T	A	Aca/Gca	-3,58	0	0	probably_damaging	0,99	deleterious	0	neutral	2,79	neutral	-2,7	neutral	-1,81	high_impact	4,12	neutral	0,72	damaging	0,08	deleterious	3,34	22,9	0,41	0,55	neutral	0,32	disease	0,72	disease	0,57	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,72	low_impact	-2,64	low_impact	-1,48	high_impact	2,71	0,56	0,9	3,51	6,79	N	0,33	N	0,69	disease_causing	0,52	0,04	rs879232447	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12631	12631	T	C	MI.19860	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	295	99	S	P	Tcc/Ccc	-0,27	0,55	0	possibly_damaging	0,81	neutral	0,2	neutral	1,37	deleterious	-3,96	deleterious	-4,92	high_impact	4,25	neutral	0,86	neutral	0,44	deleterious	3,55	23,1	0,13	0,4	disease	0,87	disease	0,89	disease	0,77	disease	0,86	7	neutral	0,89	neutral	0,2	deleterious	1	deleterious	0,71	low_impact	-1,34	medium_impact	-0,1	high_impact	2,68	0,59	0,8	8,29	12,83	N	0,48	N	0,98	disease_causing	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12631	12631	T	G	MI.19861	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	295	99	S	A	Tcc/Gcc	-0,27	0,55	0	benign	0,02	neutral	0,38	neutral	1,44	neutral	-1,47	deleterious	-2,95	medium_impact	2,34	neutral	0,77	neutral	0,71	neutral	1,57	13,67	0,38	0,5	neutral	0,27	disease	0,59	neutral	0,47	neutral	0,44	1	neutral	0,6	deleterious	0,68	neutral	-3	neutral	0,15	medium_impact	0,86	medium_impact	0,12	medium_impact	0,94	0,65	0,8	8,29	12,83	N	0,36	N	0,49	disease_causing	0,83	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12631	12631	T	A	MI.19862	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	295	99	S	T	Tcc/Acc	-0,27	0,55	0	benign	0,32	neutral	0,4	neutral	1,42	neutral	-2,07	deleterious	-2,95	high_impact	3,56	neutral	0,75	neutral	0,53	deleterious	1,96	15,98	0,31	0,5	neutral	0,26	disease	0,69	disease	0,57	disease	0,59	2	neutral	0,52	deleterious	0,54	neutral	-2	neutral	0,39	medium_impact	-0,44	medium_impact	0,14	high_impact	2,05	0,8	0,85	8,29	12,83	N	0,35	N	0,71	disease_causing	0,94	0,04	.	.	.	.	.	.	.	.	.	T12631A	found in 2 sCJD patients	+	-	Reported	2
chrM	12632	12632	C	G	MI.19863	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	296	99	S	C	tCc/tGc	2,94	0,99	0	benign	0,02	neutral	0,17	neutral	1,43	neutral	-1,71	deleterious	-4,89	medium_impact	3,01	neutral	0,75	neutral	0,5	deleterious	3,28	22,8	0,28	0,45	disease	0,55	disease	0,84	disease	0,59	disease	0,66	3	neutral	0,82	deleterious	0,58	neutral	-3	deleterious	0,7	medium_impact	0,86	medium_impact	-0,15	medium_impact	1,55	0,63	0,8	8,29	12,83	N	0,51	P	0,99	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12632	12632	C	T	MI.19864	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	296	99	S	F	tCc/tTc	2,94	0,99	0	possibly_damaging	0,89	neutral	0,81	neutral	1,45	neutral	-1,38	deleterious	-5,9	high_impact	4,25	neutral	0,76	neutral	0,42	deleterious	4,01	23,6	0,27	0,45	disease	0,89	disease	0,9	disease	0,68	disease	0,8	6	neutral	0,87	neutral	0,46	deleterious	1	deleterious	0,8	low_impact	-1,61	medium_impact	0,58	high_impact	2,68	0,49	0,8	8,29	12,83	N	0,43	N	0,99	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12632	12632	C	A	MI.19865	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	296	99	S	Y	tCc/tAc	2,94	0,99	0	probably_damaging	0,92	neutral	0,93	neutral	1,39	neutral	-2,97	deleterious	-5,9	high_impact	4,25	neutral	0,79	neutral	0,41	deleterious	3,8	23,4	0,22	0,45	disease	0,91	disease	0,89	disease	0,69	disease	0,82	6	neutral	0,91	deleterious	0,51	deleterious	2	deleterious	0,81	low_impact	-1,75	medium_impact	0,85	high_impact	2,68	0,56	0,8	8,29	12,83	N	0,4	N	0,99	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12634	12634	A	G	MI.19866	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	298	100	I	V	Atc/Gtc	-10,83	0	0,01	probably_damaging	1	neutral	0,5	neutral	1,94	neutral	0,84	neutral	-0,98	medium_impact	2,92	neutral	0,64	neutral	0,68	deleterious	2,89	21,8	0,5	0,6	neutral	0,45	neutral	0,27	disease	0,63	neutral	0,42	2	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,62	low_impact	-3,6	medium_impact	0,23	medium_impact	1,46	0,49	0,8	26,87	7,07	N	0,43	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	A12634G	Thyroid Cancer Cell Line	+	-	Reported	1
chrM	12634	12634	A	T	MI.19867	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	298	100	I	F	Atc/Ttc	-10,83	0	0,01	probably_damaging	1	neutral	0,7	neutral	0,97	deleterious	-5,81	deleterious	-3,94	high_impact	4,4	damaging	0,55	neutral	0,33	deleterious	3,71	23,3	0,27	0,45	disease	0,8	disease	0,81	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,44	high_impact	2,82	0,72	0,85	26,87	7,07	N	0,35	N	0,96	polymorphism	0,57	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12634	12634	A	C	MI.19868	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	298	100	I	L	Atc/Ctc	-10,83	0	0,01	probably_damaging	1	neutral	0,65	neutral	1,03	deleterious	-3,37	neutral	-1,97	high_impact	4,4	damaging	0,54	neutral	0,43	deleterious	3,63	23,2	0,32	0,5	neutral	0,34	disease	0,69	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,64	low_impact	-3,6	medium_impact	0,38	high_impact	2,82	0,62	0,8	26,87	7,07	N	0,39	N	0,86	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12635	12635	T	G	MI.19869	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	299	100	I	S	aTc/aGc	5,46	1	0	probably_damaging	1	neutral	0,4	neutral	0,96	deleterious	-6,64	deleterious	-5,91	high_impact	4,4	damaging	0,55	neutral	0,46	deleterious	4,13	23,8	0,25	0,45	neutral	0,36	disease	0,84	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,72	low_impact	-3,6	medium_impact	0,14	high_impact	2,82	0,52	0,8	26,87	7,07	N	0,48	N	0,96	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5953	5953	C	A	MI.1987	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	50	17	T	K	aCa/aAa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,88	deleterious	-4,2	neutral	-2,19	high_impact	3,58	neutral	0,63	damaging	0,09	deleterious	4,32	24	0,17	0,55	disease	0,6	disease	0,91	disease	0,69	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,21	0,75	0,9	3,51	6,79	N	0,49	N	0,88	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12635	12635	T	A	MI.19870	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	299	100	I	N	aTc/aAc	5,46	1	0	probably_damaging	1	neutral	0,31	neutral	0,95	deleterious	-7,66	deleterious	-6,9	high_impact	4,4	damaging	0,53	neutral	0,4	deleterious	4,26	23,9	0,23	0,45	disease	0,89	disease	0,85	disease	0,71	disease	0,81	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,04	high_impact	2,82	0,65	0,8	26,87	7,07	P	0,54	P	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12635	12635	T	C	MI.19871	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	299	100	I	T	aTc/aCc	5,46	1	0	probably_damaging	1	neutral	0,39	neutral	0,97	deleterious	-5,24	deleterious	-4,92	high_impact	4,4	damaging	0,52	neutral	0,42	deleterious	3,26	22,8	0,47	0,55	disease	0,59	disease	0,75	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,13	high_impact	2,82	0,64	0,8	26,87	7,07	P	0,55	P	0,96	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12636	12636	C	G	MI.19872	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	300	100	I	M	atC/atG	4,54	1	0	probably_damaging	1	neutral	0,22	neutral	0,97	deleterious	-5,34	deleterious	-2,96	high_impact	4,4	damaging	0,55	neutral	0,51	deleterious	3,18	22,7	0,36	0,5	disease	0,8	disease	0,62	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,73	low_impact	-3,6	medium_impact	-0,07	high_impact	2,82	0,8	0,85	26,87	7,07	P	0,53	P	0,76	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12636	12636	C	A	MI.19873	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	300	100	I	M	atC/atA	4,54	1	0	probably_damaging	1	neutral	0,22	neutral	0,97	deleterious	-5,34	deleterious	-2,96	high_impact	4,4	damaging	0,55	neutral	0,51	deleterious	3,7	23,3	0,36	0,5	disease	0,8	disease	0,62	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,73	low_impact	-3,6	medium_impact	-0,07	high_impact	2,82	0,8	0,85	26,87	7,07	P	0,54	P	0,76	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12637	12637	A	C	MI.19874	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	301	101	M	L	Ata/Cta	-6,24	0	0	benign	0,26	neutral	0,65	neutral	1,66	neutral	0,54	deleterious	-2,72	neutral_impact	0,08	neutral	0,76	neutral	0,88	deleterious	0,43	6,87	0,45	0,55	neutral	0,28	neutral	0,38	neutral	0,41	neutral	0,44	1	neutral	0,25	deleterious	0,7	neutral	-6	deleterious	0,54	medium_impact	-0,32	medium_impact	0,38	low_impact	-1,13	0,48	0,8	21,39	16,37	N	0,3	N	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12637	12637	A	G	MI.19875	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	301	101	M	V	Ata/Gta	-6,24	0	0	benign	0,04	neutral	0,5	neutral	1,5	neutral	-0,91	deleterious	-3,48	low_impact	1,48	neutral	0,8	neutral	0,71	neutral	1,53	13,46	0,49	0,55	disease	0,65	disease	0,8	disease	0,61	disease	0,61	2	neutral	0,46	deleterious	0,73	neutral	-6	deleterious	0,7	medium_impact	0,57	medium_impact	0,23	medium_impact	0,15	0,44	0,8	21,39	16,37	N	0,21	N	0,82	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12637	12637	A	T	MI.19876	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	301	101	M	L	Ata/Tta	-6,24	0	0	benign	0,26	neutral	0,65	neutral	1,66	neutral	0,54	deleterious	-2,72	neutral_impact	0,08	neutral	0,76	neutral	0,88	deleterious	0,5	7,43	0,45	0,55	neutral	0,28	neutral	0,38	neutral	0,41	neutral	0,44	1	neutral	0,25	deleterious	0,7	neutral	-6	deleterious	0,54	medium_impact	-0,32	medium_impact	0,38	low_impact	-1,13	0,48	0,8	21,39	16,37	N	0,3	N	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12638	12638	T	C	MI.19877	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	302	101	M	T	aTa/aCa	-0,04	0	0	possibly_damaging	0,54	neutral	0,39	neutral	1,46	neutral	-1,75	deleterious	-5,3	medium_impact	2,06	neutral	0,81	neutral	0,64	deleterious	2,79	21,3	0,45	0,55	disease	0,74	disease	0,79	disease	0,66	disease	0,63	3	neutral	0,61	neutral	0,43	NA	0	deleterious	0,8	medium_impact	-0,81	medium_impact	0,13	medium_impact	0,68	0,33	0,8	21,39	16,37	N	0,24	N	0,91	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12638	12638	T	A	MI.19878	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	302	101	M	K	aTa/aAa	-0,04	0	0	possibly_damaging	0,78	neutral	0,29	neutral	1,43	neutral	-2,69	deleterious	-5,55	medium_impact	3,47	neutral	0,62	damaging	0,16	deleterious	3,8	23,4	0,23	0,45	disease	0,8	disease	0,9	disease	0,74	disease	0,83	7	neutral	0,83	neutral	0,26	NA	0	deleterious	0,84	low_impact	-1,27	medium_impact	0,02	medium_impact	1,97	0,44	0,8	21,39	16,37	N	0,32	N	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12639	12639	A	T	MI.19879	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	303	101	M	I	atA/atT	4,54	1	0	benign	0,23	neutral	0,4	neutral	1,55	neutral	-0,29	deleterious	-3,56	low_impact	1,57	neutral	0,8	damaging	0,25	deleterious	3,28	22,8	0,48	0,55	disease	0,69	disease	0,86	disease	0,6	disease	0,6	2	neutral	0,52	deleterious	0,59	neutral	-6	deleterious	0,77	medium_impact	-0,25	medium_impact	0,14	medium_impact	0,23	0,63	0,8	21,39	16,37	N	0,37	N	0,83	polymorphism	0,7	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5953	5953	C	T	MI.1988	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	50	17	T	M	aCa/aTa	8,69	1	0	probably_damaging	1	neutral	0,09	neutral	2,78	deleterious	-5,65	neutral	-2,15	medium_impact	2,11	neutral	0,71	damaging	0,08	deleterious	3,81	23,4	0,31	0,55	neutral	0,49	disease	0,82	neutral	0,34	disease	0,57	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,75	low_impact	-3,58	medium_impact	-0,37	medium_impact	0,85	0,74	0,9	3,51	6,79	N	0,45	N	0,96	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12639	12639	A	C	MI.19880	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	303	101	M	I	atA/atC	4,54	1	0	benign	0,23	neutral	0,4	neutral	1,55	neutral	-0,29	deleterious	-3,56	low_impact	1,57	neutral	0,8	damaging	0,25	deleterious	3,19	22,7	0,48	0,55	disease	0,69	disease	0,86	disease	0,6	disease	0,6	2	neutral	0,52	deleterious	0,59	neutral	-6	deleterious	0,77	medium_impact	-0,25	medium_impact	0,14	medium_impact	0,23	0,63	0,8	21,39	16,37	N	0,36	N	0,83	polymorphism	0,7	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12640	12640	G	C	MI.19881	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	304	102	E	Q	Gaa/Caa	1,1	1	0	probably_damaging	1	neutral	0,3	neutral	1,45	neutral	-1,8	deleterious	-2,96	medium_impact	2,24	neutral	0,77	neutral	0,66	deleterious	3,11	22,5	0,43	0,55	disease	0,62	disease	0,61	neutral	0,48	neutral	0,47	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,03	medium_impact	0,84	0,86	0,9	7,3	11,94	N	0,37	N	0,18	disease_causing	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12640	12640	G	A	MI.19882	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	304	102	E	K	Gaa/Aaa	1,1	1	0	probably_damaging	1	neutral	0,31	neutral	1,43	neutral	-2,69	deleterious	-3,94	high_impact	3,89	neutral	0,68	damaging	0,16	deleterious	4,33	24	0,26	0,45	neutral	0,34	disease	0,9	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,04	high_impact	2,35	0,57	0,8	7,3	11,94	N	0,5	N	0,82	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12641	12641	A	C	MI.19883	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	305	102	E	A	gAa/gCa	2,71	1	0	probably_damaging	1	neutral	0,52	neutral	1,46	neutral	-1,54	deleterious	-5,91	high_impact	4,24	neutral	0,72	damaging	0,18	deleterious	3,48	23,1	0,26	0,45	disease	0,59	disease	0,82	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,25	high_impact	2,67	0,56	0,8	7,3	11,94	N	0,42	N	0,67	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12641	12641	A	G	MI.19884	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	305	102	E	G	gAa/gGa	2,71	1	0	probably_damaging	1	neutral	0,34	neutral	1,42	deleterious	-3,19	deleterious	-6,9	high_impact	3,89	neutral	0,68	damaging	0,2	deleterious	3,99	23,6	0,27	0,45	disease	0,78	disease	0,84	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,07	high_impact	2,35	0,49	0,8	7,3	11,94	N	0,43	N	0,67	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12641	12641	A	T	MI.19885	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	305	102	E	V	gAa/gTa	2,71	1	0	probably_damaging	1	neutral	0,51	neutral	1,49	neutral	-1,04	deleterious	-6,9	medium_impact	3,27	neutral	0,71	damaging	0,17	deleterious	3,95	23,6	0,25	0,45	neutral	0,48	disease	0,89	disease	0,7	disease	0,59	2	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,24	medium_impact	1,78	0,64	0,8	7,3	11,94	N	0,4	N	0,89	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12642	12642	A	T	MI.19886	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	306	102	E	D	gaA/gaT	6,84	1	0	probably_damaging	1	neutral	0,22	neutral	1,41	deleterious	-3,73	deleterious	-2,96	medium_impact	3,04	neutral	0,72	damaging	0,2	deleterious	3,61	23,2	0,32	0,5	disease	0,79	disease	0,77	disease	0,54	disease	0,64	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	-0,07	medium_impact	1,57	0,76	0,85	7,3	11,94	P	0,56	P	0,77	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12642	12642	A	C	MI.19887	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	306	102	E	D	gaA/gaC	6,84	1	0	probably_damaging	1	neutral	0,22	neutral	1,41	deleterious	-3,73	deleterious	-2,96	medium_impact	3,04	neutral	0,72	damaging	0,2	deleterious	3,49	23,1	0,32	0,5	disease	0,79	disease	0,77	disease	0,54	disease	0,64	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	-0,07	medium_impact	1,57	0,76	0,85	7,3	11,94	P	0,56	P	0,77	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12643	12643	T	A	MI.19888	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	307	103	F	I	Ttc/Atc	0,41	0,99	0	probably_damaging	1	neutral	0,54	neutral	1,06	deleterious	-5,69	deleterious	-5,85	high_impact	4,34	damaging	0,59	damaging	0,17	deleterious	4,47	24,2	0,26	0,45	disease	0,55	disease	0,88	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,27	high_impact	2,76	0,52	0,8	21,39	7,14	P	0,52	P	0,95	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12643	12643	T	G	MI.19889	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	307	103	F	V	Ttc/Gtc	0,41	0,99	0	probably_damaging	1	neutral	0,53	neutral	1,06	deleterious	-5,67	deleterious	-6,8	high_impact	4,34	damaging	0,56	damaging	0,16	deleterious	4,06	23,7	0,26	0,45	disease	0,63	disease	0,87	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,26	high_impact	2,76	0,51	0,8	21,39	7,14	N	0,49	N	0,95	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5955	5955	C	G	MI.1989	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	52	18	L	V	Cta/Gta	-2,42	0	0	probably_damaging	0,99	deleterious	0	neutral	2,7	neutral	-0,82	neutral	-1,12	high_impact	4,33	damaging	0,55	damaging	0,12	deleterious	2,86	21,7	0,23	0,55	neutral	0,41	disease	0,69	disease	0,59	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	high_impact	2,9	0,64	0,9	2,92	7,13	N	0,39	N	0,66	polymorphism	0,95	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12643	12643	T	C	MI.19890	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	307	103	F	L	Ttc/Ctc	0,41	0,99	0	probably_damaging	1	neutral	0,86	neutral	1,11	deleterious	-3,39	deleterious	-5,85	high_impact	4,34	damaging	0,53	damaging	0,16	deleterious	4,07	23,7	0,45	0,55	neutral	0,35	disease	0,82	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,43	deleterious	2	deleterious	0,71	low_impact	-3,6	medium_impact	0,67	high_impact	2,76	0,68	0,85	21,39	7,14	N	0,4	N	0,92	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12644	12644	T	C	MI.19891	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	308	103	F	S	tTc/tCc	5,69	1	0	probably_damaging	1	neutral	0,51	neutral	1,06	deleterious	-6,2	deleterious	-7,79	high_impact	4,34	neutral	0,61	damaging	0,17	deleterious	4,15	23,8	0,25	0,45	disease	0,68	disease	0,86	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,24	high_impact	2,76	0,39	0,8	21,39	7,14	P	0,57	P	0,97	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12644	12644	T	G	MI.19892	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	308	103	F	C	tTc/tGc	5,69	1	0	probably_damaging	1	neutral	0,16	neutral	1,05	deleterious	-7,68	deleterious	-7,79	high_impact	4,34	damaging	0,57	damaging	0,16	deleterious	3,96	23,6	0,3	0,45	disease	0,89	disease	0,89	disease	0,77	disease	0,85	7	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	-0,17	high_impact	2,76	0,33	0,8	21,39	7,14	P	0,56	P	0,99	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12644	12644	T	A	MI.19893	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	308	103	F	Y	tTc/tAc	5,69	1	0	probably_damaging	1	neutral	1	neutral	2,21	neutral	1,46	deleterious	-2,73	medium_impact	2,22	neutral	0,62	damaging	0,2	deleterious	4,26	23,9	0,29	0,45	neutral	0,31	disease	0,56	disease	0,72	disease	0,55	1	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,7	low_impact	-3,6	high_impact	1,89	medium_impact	0,83	0,58	0,8	21,39	7,14	N	0,5	N	0,88	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12645	12645	C	G	MI.19894	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	309	103	F	L	ttC/ttG	3,63	1	0	probably_damaging	1	neutral	0,86	neutral	1,11	deleterious	-3,39	deleterious	-5,85	high_impact	4,34	damaging	0,53	damaging	0,16	deleterious	4,22	23,9	0,45	0,55	neutral	0,35	disease	0,82	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,43	deleterious	2	deleterious	0,71	low_impact	-3,6	medium_impact	0,67	high_impact	2,76	0,68	0,85	21,39	7,14	N	0,45	N	0,92	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12645	12645	C	A	MI.19895	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	309	103	F	L	ttC/ttA	3,63	1	0	probably_damaging	1	neutral	0,86	neutral	1,11	deleterious	-3,39	deleterious	-5,85	high_impact	4,34	damaging	0,53	damaging	0,16	deleterious	4,45	24,2	0,45	0,55	neutral	0,35	disease	0,82	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,43	deleterious	2	deleterious	0,71	low_impact	-3,6	medium_impact	0,67	high_impact	2,76	0,68	0,85	21,39	7,14	N	0,46	N	0,92	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12646	12646	T	G	MI.19896	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	310	104	S	A	Tca/Gca	-1,88	0	0	probably_damaging	1	neutral	0,54	neutral	0,75	neutral	-2,3	deleterious	-2,96	medium_impact	2	damaging	0,6	neutral	0,48	neutral	1,3	12,29	0,25	0,45	disease	0,55	neutral	0,16	neutral	0,42	neutral	0,23	5	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,69	low_impact	-3,6	medium_impact	0,27	medium_impact	0,62	0,86	0,9	26,87	7,04	N	0,28	N	0,49	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12646	12646	T	C	MI.19897	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	310	104	S	P	Tca/Cca	-1,88	0	0	probably_damaging	1	neutral	0,22	neutral	0,45	deleterious	-6,78	deleterious	-4,93	high_impact	4,21	damaging	0,42	damaging	0,05	deleterious	3,8	23,4	0,18	0,45	disease	0,92	disease	0,91	disease	0,81	disease	0,88	8	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,07	high_impact	2,64	0,77	0,85	26,87	7,04	N	0,45	N	0,98	polymorphism	0,98	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12646	12646	T	A	MI.19898	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	310	104	S	T	Tca/Aca	-1,88	0	0	probably_damaging	1	neutral	0,42	neutral	0,59	deleterious	-3,4	deleterious	-2,96	medium_impact	2,68	damaging	0,58	neutral	0,3	deleterious	3,48	23,1	0,22	0,45	disease	0,8	disease	0,64	disease	0,55	disease	0,58	2	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,16	medium_impact	1,25	0,87	0,9	26,87	7,04	N	0,26	N	0,71	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12647	12647	C	G	MI.19899	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	311	104	S	W	tCa/tGa	0,87	0,8	0	probably_damaging	1	neutral	0,19	neutral	0,44	deleterious	-10,14	deleterious	-6,9	high_impact	4,21	damaging	0,48	damaging	0,07	deleterious	4,17	23,8	0,11	0,4	disease	0,98	disease	0,92	disease	0,75	disease	0,87	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,12	high_impact	2,64	0,51	0,8	26,87	7,04	N	0,37	N	0,99	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8619	8619	C	G	MI.199	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	93	31	I	M	atC/atG	0,59	0	0	benign	0,38	neutral	0,08	neutral	4,31	neutral	-1,22	neutral	-0,51	low_impact	1,11	neutral	0,94	neutral	0,77	deleterious	0,54	7,71	0,57	0,65	disease	0,62	neutral	0,29	neutral	0,2	disease	0,56	1	neutral	0,91	neutral	0,35	neutral	-6	neutral	0,36	medium_impact	-0,55	medium_impact	-0,31	medium_impact	-0,15	0,4	0,9	28,32	22,32	N	0,47	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5955	5955	C	A	MI.1990	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	52	18	L	M	Cta/Ata	-2,42	0	0	probably_damaging	1	neutral	0,15	neutral	2,71	neutral	-0,7	neutral	-0,53	low_impact	1,33	damaging	0,52	damaging	0,27	deleterious	1,93	15,75	0,2	0,55	neutral	0,31	neutral	0,37	neutral	0,2	neutral	0,4	2	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	-0,23	medium_impact	0,13	0,7	0,9	2,92	7,13	N	0,49	N	0,59	polymorphism	0,96	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12647	12647	C	T	MI.19900	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	311	104	S	L	tCa/tTa	0,87	0,8	0	probably_damaging	1	neutral	0,67	neutral	0,45	deleterious	-6,97	deleterious	-5,92	high_impact	4,21	damaging	0,47	damaging	0,04	deleterious	4,5	24,3	0,13	0,4	disease	0,9	disease	0,87	disease	0,67	disease	0,8	6	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,4	high_impact	2,64	0,88	0,9	26,87	7,04	N	0,4	N	0,99	polymorphism	0,63	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12649	12649	C	A	MI.19901	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	313	105	L	M	Ctg/Atg	-6,7	0	0	benign	0,29	neutral	0,52	neutral	1,42	neutral	-2,23	neutral	0,28	neutral_impact	0,2	neutral	0,85	neutral	0,97	neutral	1,44	13,01	0,29	0,45	disease	0,52	neutral	0,13	neutral	0,41	neutral	0,24	5	neutral	0,38	deleterious	0,62	neutral	-6	deleterious	0,67	medium_impact	-0,38	medium_impact	0,25	low_impact	-1,02	0,79	0,85	24,21	14,85	N	0,39	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12649	12649	C	G	MI.19902	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	313	105	L	V	Ctg/Gtg	-6,7	0	0	benign	0,12	neutral	0,46	neutral	1,49	neutral	-0,17	neutral	-1,65	low_impact	1,69	neutral	0,89	neutral	0,91	deleterious	1,9	15,58	0,35	0,5	neutral	0,36	neutral	0,35	disease	0,52	neutral	0,47	1	neutral	0,46	deleterious	0,67	neutral	-6	deleterious	0,66	medium_impact	0,08	medium_impact	0,19	medium_impact	0,34	0,62	0,8	24,21	14,85	N	0,34	N	0,3	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12650	12650	T	G	MI.19903	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	314	105	L	R	cTg/cGg	-1,42	0	0	probably_damaging	0,95	neutral	0,33	neutral	1,39	neutral	-1,61	deleterious	-4,17	medium_impact	2,34	neutral	0,71	neutral	0,54	deleterious	3,96	23,6	0,24	0,45	disease	0,65	disease	0,8	disease	0,67	disease	0,77	5	neutral	0,96	neutral	0,19	deleterious	1	deleterious	0,83	low_impact	-1,96	medium_impact	0,06	medium_impact	0,94	0,51	0,8	24,21	14,85	N	0,27	N	0,79	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12650	12650	T	C	MI.19904	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	314	105	L	P	cTg/cCg	-1,42	0	0	probably_damaging	0,96	neutral	0,33	neutral	1,38	deleterious	-3,14	deleterious	-5,02	medium_impact	2,34	neutral	0,63	neutral	0,44	deleterious	3,7	23,3	0,18	0,45	disease	0,83	disease	0,81	disease	0,7	disease	0,8	6	neutral	0,97	neutral	0,19	deleterious	1	deleterious	0,87	low_impact	-2,06	medium_impact	0,06	medium_impact	0,94	0,49	0,8	24,21	14,85	N	0,25	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12650	12650	T	A	MI.19905	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	314	105	L	Q	cTg/cAg	-1,42	0	0	probably_damaging	0,96	neutral	0,27	neutral	1,39	neutral	-2,83	deleterious	-3,72	low_impact	1,23	neutral	0,83	neutral	0,77	deleterious	4,04	23,7	0,27	0,45	disease	0,72	disease	0,53	neutral	0,45	disease	0,5	0	neutral	0,97	neutral	0,16	neutral	-2	deleterious	0,77	low_impact	-2,06	medium_impact	-0,01	medium_impact	-0,08	0,56	0,8	24,21	14,85	N	0,34	N	0,73	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12652	12652	T	C	MI.19906	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	316	106	W	R	Tga/Cga	-0,96	0	0	probably_damaging	1	neutral	0,36	neutral	1,52	neutral	-0,92	deleterious	-13,81	high_impact	3,92	damaging	0,51	damaging	0,07	deleterious	3,41	23	0,48	0,55	disease	0,55	disease	0,91	disease	0,85	disease	0,86	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,1	high_impact	2,38	0,32	0,8	28,36	7,17	N	0,47	N	0,97	polymorphism	0,97	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12652	12652	T	G	MI.19907	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	316	106	W	G	Tga/Gga	-0,96	0	0	probably_damaging	1	neutral	0,36	neutral	1,61	neutral	1,1	deleterious	-12,82	medium_impact	2,95	damaging	0,55	damaging	0,09	deleterious	3,73	23,3	0,39	0,5	neutral	0,41	disease	0,74	disease	0,82	disease	0,65	3	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,1	medium_impact	1,49	0,34	0,8	28,36	7,17	N	0,37	N	0,97	polymorphism	0,91	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12653	12653	G	T	MI.19908	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	317	106	W	L	tGa/tTa	7,3	1	0	probably_damaging	1	neutral	0,75	neutral	1,5	neutral	-2,59	deleterious	-12,82	high_impact	3,72	damaging	0,56	damaging	0,05	deleterious	4,15	23,8	0,25	0,45	disease	0,58	disease	0,86	disease	0,79	disease	0,8	6	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,5	high_impact	2,2	0,22	0,8	28,36	7,17	P	0,51	P	0,97	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12653	12653	G	C	MI.19909	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	317	106	W	S	tGa/tCa	7,3	1	0	probably_damaging	1	neutral	0,45	neutral	1,68	neutral	-0,64	deleterious	-13,81	medium_impact	3,03	damaging	0,52	damaging	0,11	deleterious	3,91	23,5	0,37	0,5	disease	0,51	disease	0,88	disease	0,79	disease	0,64	3	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,18	medium_impact	1,57	0,32	0,8	28,36	7,17	N	0,46	N	0,95	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5956	5956	T	G	MI.1991	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	53	18	L	R	cTa/cGa	-0,11	0	0	probably_damaging	1	deleterious	0	neutral	2,61	neutral	-2,14	neutral	-2,31	high_impact	4,12	neutral	0,61	damaging	0,11	deleterious	3,96	23,6	0,09	0,55	disease	0,65	disease	0,92	disease	0,7	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,61	0,9	2,92	7,13	N	0,33	N	0,9	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12654	12654	A	C	MI.19910	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	318	106	W	C	tgA/tgC	5	1	0,01	probably_damaging	1	neutral	0,18	neutral	1,46	deleterious	-4,68	deleterious	-12,82	high_impact	4,27	damaging	0,52	damaging	0,06	deleterious	3,86	23,5	0,27	0,45	disease	0,94	disease	0,91	disease	0,82	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,13	high_impact	2,7	0,24	0,8	28,36	7,17	N	0,5	N	0,98	disease_causing	1	0,12	rs386829162	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12654	12654	A	T	MI.19911	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	318	106	W	C	tgA/tgT	5	1	0,01	probably_damaging	1	neutral	0,18	neutral	1,46	deleterious	-4,68	deleterious	-12,82	high_impact	4,27	damaging	0,52	damaging	0,06	deleterious	3,95	23,6	0,27	0,45	disease	0,94	disease	0,91	disease	0,82	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,13	high_impact	2,7	0,24	0,8	28,36	7,17	N	0,51	P	0,98	disease_causing	1	0,12	rs386829162	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12655	12655	T	C	MI.19912	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	319	107	Y	H	Tat/Cat	1,1	1	0	probably_damaging	1	neutral	0,54	neutral	-1,44	deleterious	-9,8	deleterious	-4,93	high_impact	4,42	damaging	0,33	neutral	0,32	deleterious	3,45	23	0,4	0,5	disease	0,9	disease	0,82	disease	0,84	disease	0,83	7	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,27	high_impact	2,83	0,33	0,8	28,03	7,1	P	0,77	P	0,98	disease_causing	0,96	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12655	12655	T	A	MI.19913	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	319	107	Y	N	Tat/Aat	1,1	1	0	probably_damaging	1	neutral	0,31	neutral	-1,45	deleterious	-10,76	deleterious	-8,88	high_impact	4,42	damaging	0,23	neutral	0,42	deleterious	3,91	23,5	0,29	0,45	disease	0,92	disease	0,86	disease	0,8	disease	0,84	7	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,04	high_impact	2,83	0,19	0,8	28,03	7,1	P	0,87	P	0,99	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12655	12655	T	G	MI.19914	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	319	107	Y	D	Tat/Gat	1,1	1	0	probably_damaging	1	neutral	0,21	neutral	-1,45	deleterious	-11,23	deleterious	-9,86	high_impact	4,42	damaging	0,38	neutral	0,38	deleterious	3,84	23,4	0,17	0,45	disease	0,94	disease	0,85	disease	0,86	disease	0,84	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,09	high_impact	2,83	0,34	0,8	28,03	7,1	P	0,68	P	0,96	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12656	12656	A	T	MI.19915	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	320	107	Y	F	tAt/tTt	4,54	1	0	probably_damaging	1	neutral	0,7	neutral	-1,4	deleterious	-7,53	deleterious	-3,94	high_impact	4,08	damaging	0,29	neutral	0,36	deleterious	3,07	22,4	0,3	0,45	disease	0,8	disease	0,82	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,44	high_impact	2,52	0,43	0,8	28,03	7,1	P	0,87	P	0,8	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12656	12656	A	C	MI.19916	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	320	107	Y	S	tAt/tCt	4,54	1	0	probably_damaging	1	neutral	0,41	neutral	-1,45	deleterious	-10,51	deleterious	-8,88	high_impact	4,42	damaging	0,34	neutral	0,53	deleterious	3,39	23	0,25	0,45	disease	0,76	disease	0,85	disease	0,8	disease	0,77	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,15	high_impact	2,83	0,29	0,8	28,03	7,1	P	0,7	P	0,97	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12656	12656	A	G	MI.19917	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	320	107	Y	C	tAt/tGt	4,54	1	0	probably_damaging	1	neutral	0,18	neutral	-1,45	deleterious	-11,98	deleterious	-8,88	high_impact	4,42	damaging	0,31	damaging	0,28	deleterious	3,21	22,7	0,36	0,5	disease	0,94	disease	0,88	disease	0,84	disease	0,84	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,13	high_impact	2,83	0,17	0,8	28,03	7,1	P	0,69	P	1	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12658	12658	A	G	MI.19918	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	322	108	M	V	Ata/Gta	-1,65	0	0	probably_damaging	0,99	neutral	0,5	neutral	0,15	deleterious	-5,69	deleterious	-3,94	high_impact	3,68	damaging	0,41	damaging	0,09	deleterious	2,52	19,58	0,52	0,6	disease	0,75	disease	0,83	disease	0,74	disease	0,76	5	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,77	low_impact	-2,64	medium_impact	0,23	high_impact	2,16	0,55	0,8	28,86	7,23	N	0,38	N	0,95	disease_causing	0,85	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12658	12658	A	C	MI.19919	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	322	108	M	L	Ata/Cta	-1,65	0	0	probably_damaging	0,98	neutral	0,71	neutral	0,28	deleterious	-3,8	deleterious	-2,96	medium_impact	3,48	damaging	0,43	damaging	0,07	deleterious	3,05	22,4	0,42	0,55	disease	0,57	disease	0,82	disease	0,66	disease	0,69	4	deleterious	0,98	neutral	0,37	deleterious	1	deleterious	0,71	low_impact	-2,35	medium_impact	0,45	medium_impact	1,98	0,48	0,8	28,86	7,23	N	0,33	N	0,98	disease_causing	0,82	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5956	5956	T	C	MI.1992	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	53	18	L	P	cTa/cCa	-0,11	0	0	probably_damaging	1	deleterious	0	neutral	2,61	neutral	-2,13	deleterious	-2,73	high_impact	4,33	damaging	0,46	damaging	0,14	deleterious	3,83	23,4	0,1	0,55	disease	0,75	disease	0,88	disease	0,7	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	2,9	0,44	0,9	2,92	7,13	N	0,44	N	0,83	disease_causing	0,95	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12658	12658	A	T	MI.19920	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	322	108	M	L	Ata/Tta	-1,65	0	0	probably_damaging	0,98	neutral	0,71	neutral	0,28	deleterious	-3,8	deleterious	-2,96	medium_impact	3,48	damaging	0,43	damaging	0,07	deleterious	3,08	22,5	0,42	0,55	disease	0,57	disease	0,82	disease	0,66	disease	0,69	4	deleterious	0,98	neutral	0,37	deleterious	1	deleterious	0,71	low_impact	-2,35	medium_impact	0,45	medium_impact	1,98	0,48	0,8	28,86	7,23	N	0,33	N	0,98	disease_causing	0,82	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12659	12659	T	C	MI.19921	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	323	108	M	T	aTa/aCa	5,46	1	0	probably_damaging	1	neutral	0,38	neutral	0,12	deleterious	-7,49	deleterious	-5,92	high_impact	4,38	damaging	0,44	damaging	0,08	deleterious	2,83	21,5	0,41	0,5	disease	0,76	disease	0,9	disease	0,74	disease	0,78	6	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,12	high_impact	2,8	0,41	0,8	28,86	7,23	P	0,55	P	0,99	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12659	12659	T	A	MI.19922	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	323	108	M	K	aTa/aAa	5,46	1	0	probably_damaging	1	neutral	0,29	neutral	0,11	deleterious	-8,61	deleterious	-5,92	high_impact	4,38	damaging	0,42	damaging	0,05	deleterious	3,76	23,3	0,18	0,45	disease	0,82	disease	0,9	disease	0,8	disease	0,84	7	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,02	high_impact	2,8	0,33	0,8	28,86	7,23	P	0,62	P	1	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12660	12660	A	T	MI.19923	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	324	108	M	I	atA/atT	3,63	1	0	probably_damaging	0,99	neutral	0,46	neutral	0,17	deleterious	-5,31	deleterious	-3,94	medium_impact	3,13	damaging	0,43	damaging	0,12	deleterious	3,26	22,8	0,48	0,55	disease	0,62	disease	0,88	disease	0,72	disease	0,77	5	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,82	low_impact	-2,64	medium_impact	0,19	medium_impact	1,66	0,69	0,85	28,86	7,23	P	0,63	P	0,94	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12660	12660	A	C	MI.19924	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	324	108	M	I	atA/atC	3,63	1	0	probably_damaging	0,99	neutral	0,46	neutral	0,17	deleterious	-5,31	deleterious	-3,94	medium_impact	3,13	damaging	0,43	damaging	0,12	deleterious	3,17	22,7	0,48	0,55	disease	0,62	disease	0,88	disease	0,72	disease	0,77	5	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,82	low_impact	-2,64	medium_impact	0,19	medium_impact	1,66	0,69	0,85	28,86	7,23	P	0,62	P	0,94	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12661	12661	A	C	MI.19925	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	325	109	N	H	Aac/Cac	-0,5	0	0	benign	0,02	neutral	0,56	neutral	1,63	neutral	0,83	neutral	4,35	neutral_impact	-1,34	neutral	0,78	neutral	0,96	neutral	-1,72	0	0,66	0,7	neutral	0,45	neutral	0,07	neutral	0,11	neutral	0,26	5	neutral	0,41	deleterious	0,77	neutral	-6	neutral	0,11	medium_impact	0,86	medium_impact	0,29	low_impact	-2,43	0,49	0,8	17,74	16,94	N	0,36	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12661	12661	A	G	MI.19926	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	325	109	N	D	Aac/Gac	-0,5	0	0	benign	0,01	neutral	0,21	neutral	1,63	neutral	0,87	neutral	-1,91	low_impact	0,99	neutral	0,79	neutral	0,75	neutral	1,78	14,88	0,81	0,85	neutral	0,46	neutral	0,37	neutral	0,42	neutral	0,46	1	neutral	0,79	deleterious	0,6	neutral	-6	neutral	0,15	medium_impact	1,15	medium_impact	-0,09	medium_impact	-0,3	0,59	0,8	17,74	16,94	N	0,4	N	0,03	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12661	12661	A	T	MI.19927	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	325	109	N	Y	Aac/Tac	-0,5	0	0	possibly_damaging	0,5	neutral	1	neutral	1,54	neutral	-1,89	neutral	0,04	low_impact	1,34	neutral	0,87	neutral	0,94	neutral	1,67	14,26	0,46	0,55	disease	0,75	disease	0,52	neutral	0,23	disease	0,5	0	neutral	0,5	deleterious	0,75	neutral	-3	neutral	0,37	medium_impact	-0,75	high_impact	1,89	medium_impact	0,02	0,56	0,8	17,74	16,94	N	0,26	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12662	12662	A	G	MI.19928	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	326	109	N	S	aAc/aGc	-0,73	0	0	benign	0,01	neutral	0,42	neutral	1,73	neutral	1,82	neutral	-1,69	neutral_impact	-0,36	neutral	0,83	neutral	0,92	neutral	-0,15	1,37	0,71	0,75	neutral	0,37	neutral	0,21	neutral	0,19	neutral	0,37	3	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,16	low_impact	-1,53	0,42	0,8	17,74	16,94	N	0,43	N	0,09	polymorphism	1	0,02	rs879105366	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12662	12662	A	T	MI.19929	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	326	109	N	I	aAc/aTc	-0,73	0	0	possibly_damaging	0,47	neutral	0,4	neutral	1,54	neutral	-1,59	deleterious	-3,9	low_impact	1,59	neutral	0,74	neutral	0,68	deleterious	1,9	15,58	0,49	0,55	disease	0,72	disease	0,68	neutral	0,41	disease	0,51	0	neutral	0,56	neutral	0,47	neutral	-3	deleterious	0,45	medium_impact	-0,7	medium_impact	0,14	medium_impact	0,25	0,41	0,8	17,74	16,94	N	0,29	N	0,38	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5956	5956	T	A	MI.1993	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	53	18	L	Q	cTa/cAa	-0,11	0	0	probably_damaging	1	deleterious	0	neutral	2,61	neutral	-2,21	neutral	-2,26	medium_impact	3,31	damaging	0,59	damaging	0,13	deleterious	4,06	23,7	0,1	0,55	disease	0,5	disease	0,86	disease	0,57	disease	0,72	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	medium_impact	1,96	0,61	0,9	2,92	7,13	N	0,29	N	0,82	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12662	12662	A	C	MI.19930	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	326	109	N	T	aAc/aCc	-0,73	0	0	benign	0,18	neutral	0,39	neutral	1,6	neutral	0,31	deleterious	-2,68	low_impact	1,25	neutral	0,85	neutral	0,9	neutral	1,34	12,48	0,67	0,7	disease	0,62	neutral	0,39	neutral	0,41	disease	0,61	2	neutral	0,53	deleterious	0,61	neutral	-6	neutral	0,29	medium_impact	-0,12	medium_impact	0,13	medium_impact	-0,06	0,54	0,8	17,74	16,94	N	0,34	N	0,19	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12663	12663	C	A	MI.19931	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	327	109	N	K	aaC/aaA	0,18	0	0	benign	0,18	neutral	0,29	neutral	1,65	neutral	1,1	neutral	-1,72	neutral_impact	0,07	neutral	0,79	neutral	0,73	deleterious	2,42	18,95	0,77	0,8	neutral	0,37	neutral	0,49	neutral	0,23	neutral	0,44	1	neutral	0,66	deleterious	0,56	neutral	-6	neutral	0,28	medium_impact	-0,12	medium_impact	0,02	low_impact	-1,14	0,64	0,8	17,74	16,94	N	0,34	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12663	12663	C	G	MI.19932	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	327	109	N	K	aaC/aaG	0,18	0	0	benign	0,18	neutral	0,29	neutral	1,65	neutral	1,1	neutral	-1,72	neutral_impact	0,07	neutral	0,79	neutral	0,73	deleterious	2,02	16,32	0,77	0,8	neutral	0,37	neutral	0,49	neutral	0,23	neutral	0,44	1	neutral	0,66	deleterious	0,56	neutral	-6	neutral	0,28	medium_impact	-0,12	medium_impact	0,02	low_impact	-1,14	0,64	0,8	17,74	16,94	N	0,33	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12664	12664	T	C	MI.19933	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	328	110	S	P	Tca/Cca	-2,11	0	0	probably_damaging	1	neutral	0,2	neutral	1,39	deleterious	-3,33	deleterious	-4,45	medium_impact	3,08	neutral	0,72	damaging	0,19	deleterious	3,92	23,5	0,38	0,5	disease	0,8	disease	0,87	neutral	0,43	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	-0,1	medium_impact	1,61	0,57	0,8	2,49	9,04	N	0,34	N	0,98	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12664	12664	T	G	MI.19934	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	328	110	S	A	Tca/Gca	-2,11	0	0	probably_damaging	1	neutral	0,51	neutral	1,45	neutral	-1,38	deleterious	-2,68	low_impact	1,7	neutral	0,82	neutral	0,88	deleterious	2,2	17,48	0,59	0,65	disease	0,67	neutral	0,31	neutral	0,2	disease	0,61	2	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,24	medium_impact	0,35	0,74	0,85	2,49	9,04	N	0,32	N	0,49	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12664	12664	T	A	MI.19935	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	328	110	S	T	Tca/Aca	-2,11	0	0	probably_damaging	1	neutral	0,39	neutral	1,43	neutral	-1,95	deleterious	-2,51	low_impact	1,41	neutral	0,83	neutral	0,95	deleterious	2,73	21	0,63	0,65	disease	0,65	neutral	0,49	neutral	0,19	disease	0,55	1	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	0,13	medium_impact	0,09	0,8	0,85	2,49	9,04	N	0,38	N	0,71	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12665	12665	C	G	MI.19936	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	329	110	S	W	tCa/tGa	-0,5	0	0	probably_damaging	1	neutral	0,19	neutral	1,37	deleterious	-5,86	deleterious	-6,46	high_impact	3,77	neutral	0,75	damaging	0,13	deleterious	4,25	23,9	0,32	0,5	disease	0,97	disease	0,86	disease	0,54	disease	0,84	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,12	high_impact	2,24	0,55	0,8	2,49	9,04	N	0,3	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12665	12665	C	T	MI.19937	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	329	110	S	L	tCa/tTa	-0,5	0	0	probably_damaging	1	neutral	0,65	neutral	1,4	neutral	-2,73	deleterious	-5,42	medium_impact	3,08	neutral	0,83	neutral	0,3	deleterious	4,56	24,4	0,42	0,55	disease	0,81	disease	0,8	neutral	0,44	disease	0,71	4	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,38	medium_impact	1,61	0,87	0,9	2,49	9,04	N	0,21	N	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12667	12667	G	A	MI.19938	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	331	111	D	N	Gac/Aac	-1,65	0	0	probably_damaging	1	neutral	0,32	neutral	0,23	deleterious	-5,64	deleterious	-4,92	high_impact	3,81	damaging	0,57	damaging	0,12	deleterious	4,08	23,7	0,63	0,7	disease	0,73	disease	0,89	disease	0,75	disease	0,79	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,05	high_impact	2,28	0,72	0,85	25,87	7,14	N	0,35	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12667	12667	G	T	MI.19939	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	331	111	D	Y	Gac/Tac	-1,65	0	0	probably_damaging	1	neutral	1	neutral	0,19	deleterious	-8,83	deleterious	-8,86	high_impact	3,55	neutral	0,63	damaging	0,11	deleterious	3,78	23,4	0,23	0,45	disease	0,88	disease	0,94	disease	0,76	disease	0,83	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,9	low_impact	-3,6	high_impact	1,89	high_impact	2,04	0,33	0,8	25,87	7,14	N	0,32	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5958	5958	T	A	MI.1994	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	55	19	Y	N	Tac/Aac	-20	0	0	probably_damaging	1	deleterious	0	neutral	2	deleterious	-7,45	deleterious	-3,8	high_impact	5	neutral	0,64	damaging	0,12	deleterious	3,83	23,4	0,22	0,55	disease	0,93	disease	0,92	disease	0,69	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,21	0,9	3,51	6,69	P	0,6	P	0,94	polymorphism	0,9	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12667	12667	G	C	MI.19940	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	331	111	D	H	Gac/Cac	-1,65	0	0	probably_damaging	1	neutral	0,53	neutral	0,2	deleterious	-7,51	deleterious	-6,88	high_impact	4,36	neutral	0,61	damaging	0,1	deleterious	3,54	23,1	0,47	0,55	disease	0,77	disease	0,89	disease	0,8	disease	0,81	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,26	high_impact	2,78	0,57	0,8	25,87	7,14	N	0,42	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12668	12668	A	G	MI.19941	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	332	111	D	G	gAc/gGc	5,92	1	0	probably_damaging	1	neutral	0,35	neutral	0,21	deleterious	-6,46	deleterious	-6,89	high_impact	4,36	damaging	0,58	damaging	0,13	deleterious	3,81	23,4	0,37	0,5	disease	0,86	disease	0,88	disease	0,76	disease	0,84	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,08	high_impact	2,78	0,36	0,8	25,87	7,14	P	0,59	P	0,98	disease_causing	0,96	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12668	12668	A	C	MI.19942	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	332	111	D	A	gAc/gCc	5,92	1	0	probably_damaging	1	neutral	0,52	neutral	0,21	deleterious	-6,52	deleterious	-7,87	high_impact	3,81	neutral	0,62	damaging	0,18	deleterious	3,47	23	0,31	0,5	disease	0,74	disease	0,87	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,25	high_impact	2,28	0,49	0,8	25,87	7,14	P	0,55	P	0,94	disease_causing	0,94	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12668	12668	A	T	MI.19943	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	332	111	D	V	gAc/gTc	5,92	1	0	probably_damaging	1	neutral	0,5	neutral	0,19	deleterious	-8,3	deleterious	-8,86	high_impact	4,36	damaging	0,55	damaging	0,1	deleterious	3,58	23,2	0,27	0,45	disease	0,76	disease	0,93	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,23	high_impact	2,78	0,33	0,8	25,87	7,14	P	0,53	P	0,99	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12669	12669	C	A	MI.19944	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	333	111	D	E	gaC/gaA	8,44	1	0	probably_damaging	1	neutral	0,27	neutral	0,49	neutral	-2,82	deleterious	-3,92	medium_impact	2,79	neutral	0,66	damaging	0,25	deleterious	4,09	23,7	0,54	0,6	neutral	0,43	disease	0,75	disease	0,51	neutral	0,49	0	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	-0,01	medium_impact	1,35	0,57	0,8	25,87	7,14	P	0,51	P	0,91	disease_causing	0,83	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12669	12669	C	G	MI.19945	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	333	111	D	E	gaC/gaG	8,44	1	0	probably_damaging	1	neutral	0,27	neutral	0,49	neutral	-2,82	deleterious	-3,92	medium_impact	2,79	neutral	0,66	damaging	0,25	deleterious	3,77	23,4	0,54	0,6	neutral	0,43	disease	0,75	disease	0,51	neutral	0,49	0	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	-0,01	medium_impact	1,35	0,57	0,8	25,87	7,14	P	0,51	P	0,91	disease_causing	0,83	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12670	12670	C	T	MI.19946	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	334	112	P	S	Cca/Tca	-0,96	0	0	probably_damaging	1	neutral	0,42	neutral	1,21	neutral	-2,78	deleterious	-7,53	high_impact	3,58	neutral	0,67	damaging	0,11	deleterious	3,72	23,3	0,52	0,6	disease	0,58	disease	0,83	disease	0,57	disease	0,64	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,16	high_impact	2,07	0,17	0,8	15,26	6,92	N	0,26	N	0,65	disease_causing	0,96	0,06	rs878876419	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12670	12670	C	A	MI.19947	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	334	112	P	T	Cca/Aca	-0,96	0	0	probably_damaging	1	neutral	0,4	neutral	1,19	deleterious	-3,17	deleterious	-7,5	high_impact	3,73	neutral	0,62	damaging	0,1	deleterious	3,69	23,3	0,4	0,5	neutral	0,39	disease	0,87	disease	0,59	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,14	high_impact	2,2	0,75	0,85	15,26	6,92	N	0,3	N	0,77	disease_causing	0,96	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12670	12670	C	G	MI.19948	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	334	112	P	A	Cca/Gca	-0,96	0	0	probably_damaging	1	neutral	0,52	neutral	1,21	neutral	-2,82	deleterious	-7,5	high_impact	3,93	damaging	0,59	damaging	0,11	deleterious	2,94	22	0,43	0,55	disease	0,67	disease	0,73	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,25	high_impact	2,39	0,77	0,85	15,26	6,92	N	0,27	N	0,64	disease_causing	0,94	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12671	12671	C	A	MI.19949	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	335	112	P	Q	cCa/cAa	2,71	0,13	0	probably_damaging	1	neutral	0,3	neutral	1,2	neutral	-2,95	deleterious	-7,53	high_impact	3,93	neutral	0,64	damaging	0,12	deleterious	3,98	23,6	0,38	0,5	disease	0,67	disease	0,87	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,03	high_impact	2,39	0,54	0,8	15,26	6,92	N	0,4	N	0,86	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5958	5958	T	C	MI.1995	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	55	19	Y	H	Tac/Cac	-20	0	0	probably_damaging	1	deleterious	0	neutral	1,97	deleterious	-6,38	neutral	-2,11	high_impact	4,11	neutral	0,7	damaging	0,11	deleterious	3,39	23	0,3	0,55	disease	0,87	disease	0,87	disease	0,71	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	2,7	0,29	0,9	3,51	6,69	N	0,31	N	0,61	polymorphism	0,99	0,29	.	.	.	.	.	colonic crypt clone	.	.	.	.	.	.	.	.	.
chrM	12671	12671	C	G	MI.19950	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	335	112	P	R	cCa/cGa	2,71	0,13	0	probably_damaging	1	neutral	0,36	neutral	1,19	deleterious	-3,17	deleterious	-8,48	medium_impact	3,48	neutral	0,62	damaging	0,09	deleterious	3,46	23	0,42	0,55	disease	0,56	disease	0,92	disease	0,64	disease	0,73	5	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,1	medium_impact	1,98	0,7	0,85	15,26	6,92	N	0,37	N	0,88	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12671	12671	C	T	MI.19951	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	335	112	P	L	cCa/cTa	2,71	0,13	0	probably_damaging	1	neutral	0,65	neutral	1,21	neutral	-2,82	deleterious	-9,21	medium_impact	2,75	neutral	0,65	neutral	0,46	deleterious	4,24	23,9	0,42	0,5	disease	0,74	disease	0,89	disease	0,51	disease	0,52	0	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,38	medium_impact	1,31	0,75	0,85	15,26	6,92	N	0,33	N	0,94	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12673	12673	A	G	MI.19952	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	337	113	N	D	Aac/Gac	-11,28	0	0	possibly_damaging	0,89	neutral	0,21	neutral	1,35	neutral	-2,57	deleterious	-3	low_impact	1,8	neutral	0,85	neutral	0,78	deleterious	2,63	20,4	0,82	0,85	disease	0,6	disease	0,55	neutral	0,34	neutral	0,5	0	neutral	0,93	neutral	0,16	neutral	-3	deleterious	0,72	low_impact	-1,61	medium_impact	-0,09	medium_impact	0,44	0,53	0,8	8,46	9,91	N	0,37	N	0,71	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12673	12673	A	T	MI.19953	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	337	113	N	Y	Aac/Tac	-11,28	0	0	probably_damaging	0,99	neutral	1	neutral	1,37	neutral	-2,05	neutral	-2,36	low_impact	0,94	neutral	0,87	neutral	0,98	deleterious	1,99	16,14	0,48	0,55	disease	0,7	neutral	0,47	neutral	0,27	disease	0,6	2	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,73	low_impact	-2,64	high_impact	1,89	medium_impact	-0,34	0,49	0,8	8,46	9,91	N	0,27	N	0,18	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12673	12673	A	C	MI.19954	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	337	113	N	H	Aac/Cac	-11,28	0	0	probably_damaging	0,99	neutral	0,54	neutral	1,5	neutral	-0,58	neutral	-1,12	low_impact	1,28	neutral	0,83	neutral	0,96	neutral	1,64	14,05	0,64	0,7	disease	0,53	neutral	0,33	neutral	0,31	neutral	0,44	1	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,69	low_impact	-2,64	medium_impact	0,27	medium_impact	-0,03	0,45	0,8	8,46	9,91	N	0,33	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12674	12674	A	C	MI.19955	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	338	113	N	T	aAc/aCc	-10,6	0	0	probably_damaging	0,94	neutral	0,39	neutral	1,35	neutral	-2,37	deleterious	-3,68	medium_impact	3,01	neutral	0,8	neutral	0,62	deleterious	3,2	22,7	0,63	0,65	disease	0,63	disease	0,62	neutral	0,42	disease	0,51	0	neutral	0,94	neutral	0,23	deleterious	1	deleterious	0,73	low_impact	-1,88	medium_impact	0,13	medium_impact	1,55	0,58	0,8	8,46	9,91	N	0,3	N	0,49	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12674	12674	A	G	MI.19956	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	338	113	N	S	aAc/aGc	-10,6	0	0	possibly_damaging	0,86	neutral	0,41	neutral	1,37	neutral	-2,05	deleterious	-2,93	medium_impact	2,87	neutral	0,82	neutral	0,72	deleterious	2,82	21,5	0,77	0,8	disease	0,51	disease	0,52	neutral	0,43	neutral	0,5	0	neutral	0,86	neutral	0,28	NA	0	deleterious	0,72	low_impact	-1,5	medium_impact	0,15	medium_impact	1,42	0,24	0,8	8,46	9,91	N	0,33	N	0,45	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12674	12674	A	T	MI.19957	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	338	113	N	I	aAc/aTc	-10,6	0	0	probably_damaging	0,98	neutral	0,39	neutral	1,32	deleterious	-3,43	deleterious	-5,35	high_impact	3,56	neutral	0,8	neutral	0,54	deleterious	3,66	23,2	0,39	0,5	disease	0,54	disease	0,8	neutral	0,45	disease	0,67	3	neutral	0,98	neutral	0,21	deleterious	2	deleterious	0,75	low_impact	-2,35	medium_impact	0,13	high_impact	2,05	0,32	0,8	8,46	9,91	N	0,31	N	0,9	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12675	12675	C	G	MI.19958	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	339	113	N	K	aaC/aaG	1,33	0	0	benign	0,26	neutral	0,3	neutral	1,42	neutral	-1,23	deleterious	-3,37	low_impact	1,25	neutral	0,88	neutral	0,67	deleterious	2,76	21,1	0,83	0,85	neutral	0,5	disease	0,63	neutral	0,37	neutral	0,48	0	neutral	0,64	deleterious	0,52	neutral	-6	deleterious	0,73	medium_impact	-0,32	medium_impact	0,03	medium_impact	-0,06	0,67	0,85	8,46	9,91	N	0,34	N	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12675	12675	C	A	MI.19959	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	339	113	N	K	aaC/aaA	1,33	0	0	benign	0,26	neutral	0,3	neutral	1,42	neutral	-1,23	deleterious	-3,37	low_impact	1,25	neutral	0,88	neutral	0,67	deleterious	3,26	22,8	0,83	0,85	neutral	0,5	disease	0,63	neutral	0,37	neutral	0,48	0	neutral	0,64	deleterious	0,52	neutral	-6	deleterious	0,73	medium_impact	-0,32	medium_impact	0,03	medium_impact	-0,06	0,67	0,85	8,46	9,91	N	0,34	N	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5958	5958	T	G	MI.1996	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	55	19	Y	D	Tac/Gac	-20	0	0	probably_damaging	1	deleterious	0	neutral	1,96	deleterious	-8,49	deleterious	-4,22	high_impact	4,66	neutral	0,71	damaging	0,11	deleterious	3,74	23,3	0,16	0,55	disease	0,96	disease	0,92	disease	0,76	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,2	0,22	0,9	3,51	6,69	N	0,47	N	0,98	polymorphism	0,93	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12676	12676	A	C	MI.19960	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	340	114	I	L	Att/Ctt	-4,4	0	0	possibly_damaging	0,49	neutral	0,7	neutral	1,39	neutral	-1,54	neutral	-1,25	low_impact	1,51	neutral	0,76	neutral	0,87	deleterious	2,21	17,56	0,45	0,55	disease	0,52	disease	0,67	neutral	0,33	neutral	0,49	0	neutral	0,4	deleterious	0,61	neutral	-3	deleterious	0,69	medium_impact	-0,73	medium_impact	0,44	medium_impact	0,18	0,55	0,8	4,98	10,41	N	0,23	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12676	12676	A	T	MI.19961	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	340	114	I	F	Att/Ttt	-4,4	0	0	probably_damaging	0,94	neutral	0,77	neutral	1,31	deleterious	-3,11	deleterious	-3,42	medium_impact	2,8	neutral	0,73	damaging	0,12	deleterious	3,42	23	0,35	0,5	disease	0,63	disease	0,83	disease	0,64	disease	0,73	5	neutral	0,94	neutral	0,42	deleterious	1	deleterious	0,79	low_impact	-1,88	medium_impact	0,52	medium_impact	1,36	0,61	0,8	4,98	10,41	N	0,16	N	0,96	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12676	12676	A	G	MI.19962	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	340	114	I	V	Att/Gtt	-4,4	0	0	possibly_damaging	0,62	neutral	0,5	neutral	1,38	neutral	-1,63	neutral	-0,87	medium_impact	2,52	neutral	0,77	neutral	0,31	neutral	1,66	14,18	0,53	0,6	disease	0,76	neutral	0,39	neutral	0,37	disease	0,65	3	neutral	0,6	neutral	0,44	NA	0	deleterious	0,7	medium_impact	-0,95	medium_impact	0,23	medium_impact	1,1	0,46	0,8	4,98	10,41	N	0,26	N	0,74	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12677	12677	T	G	MI.19963	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	341	114	I	S	aTt/aGt	3,17	0,99	0	probably_damaging	0,94	neutral	0,42	neutral	1,37	neutral	-1,83	deleterious	-5,27	medium_impact	2,92	neutral	0,75	damaging	0,15	deleterious	4,15	23,8	0,35	0,5	disease	0,7	disease	0,83	disease	0,6	disease	0,69	4	neutral	0,93	neutral	0,24	deleterious	1	deleterious	0,81	low_impact	-1,88	medium_impact	0,16	medium_impact	1,46	0,57	0,8	4,98	10,41	N	0,34	N	0,96	disease_causing	0,96	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12677	12677	T	A	MI.19964	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	341	114	I	N	aTt/aAt	3,17	0,99	0	probably_damaging	0,98	neutral	0,32	neutral	1,37	neutral	-1,84	deleterious	-6,26	medium_impact	2,75	neutral	0,75	damaging	0,17	deleterious	4,29	24	0,37	0,5	disease	0,64	disease	0,88	disease	0,62	disease	0,7	4	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,82	low_impact	-2,35	medium_impact	0,05	medium_impact	1,31	0,58	0,8	4,98	10,41	N	0,36	N	0,99	disease_causing	0,96	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12677	12677	T	C	MI.19965	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	341	114	I	T	aTt/aCt	3,17	0,99	0	probably_damaging	0,94	neutral	0,39	neutral	1,34	neutral	-2,49	deleterious	-4,37	medium_impact	2,75	neutral	0,82	damaging	0,18	deleterious	3,23	22,8	0,35	0,5	neutral	0,48	disease	0,75	disease	0,62	disease	0,56	1	neutral	0,94	neutral	0,23	deleterious	1	deleterious	0,74	low_impact	-1,88	medium_impact	0,13	medium_impact	1,31	0,48	0,8	4,98	10,41	N	0,33	N	0,96	disease_causing	0,87	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12678	12678	T	A	MI.19966	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	342	114	I	M	atT/atA	2,94	0,99	0	possibly_damaging	0,61	neutral	0,25	neutral	1,35	neutral	-2,12	neutral	-1,92	low_impact	1,87	neutral	0,8	neutral	0,82	neutral	1,58	13,73	0,46	0,55	disease	0,73	neutral	0,21	neutral	0,28	disease	0,52	0	neutral	0,76	neutral	0,32	neutral	-3	deleterious	0,72	medium_impact	-0,93	medium_impact	-0,03	medium_impact	0,51	0,66	0,8	4,98	10,41	P	0,5	N	0,76	polymorphism	0,75	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12678	12678	T	G	MI.19967	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	342	114	I	M	atT/atG	2,94	0,99	0	possibly_damaging	0,61	neutral	0,25	neutral	1,35	neutral	-2,12	neutral	-1,92	low_impact	1,87	neutral	0,8	neutral	0,82	neutral	1,34	12,48	0,46	0,55	disease	0,73	neutral	0,21	neutral	0,28	disease	0,52	0	neutral	0,76	neutral	0,32	neutral	-3	deleterious	0,72	medium_impact	-0,93	medium_impact	-0,03	medium_impact	0,51	0,66	0,8	4,98	10,41	P	0,5	N	0,76	polymorphism	0,75	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12679	12679	A	G	MI.19968	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	343	115	N	D	Aat/Gat	-9,91	0	0	benign	0,08	neutral	0,24	neutral	1,52	neutral	-0,77	deleterious	-4	low_impact	1,82	neutral	0,84	neutral	0,84	deleterious	2,59	20,2	0,79	0,8	disease	0,74	disease	0,65	neutral	0,39	disease	0,53	1	neutral	0,73	deleterious	0,58	neutral	-6	deleterious	0,76	medium_impact	0,26	medium_impact	-0,04	medium_impact	0,46	0,63	0,8	17,91	16,66	N	0,36	N	0,39	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12679	12679	A	T	MI.19969	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	343	115	N	Y	Aat/Tat	-9,91	0	0	probably_damaging	0,98	neutral	1	neutral	1,43	deleterious	-3,41	deleterious	-7,46	high_impact	3,6	neutral	0,81	neutral	0,42	deleterious	3,58	23,2	0,45	0,55	disease	0,75	disease	0,88	disease	0,6	disease	0,71	4	deleterious	0,98	deleterious	0,51	deleterious	2	deleterious	0,82	low_impact	-2,35	high_impact	1,89	high_impact	2,09	0,43	0,8	17,91	16,66	N	0,24	N	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5959	5959	A	G	MI.1997	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	56	19	Y	C	tAc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	1,97	deleterious	-7,48	deleterious	-3,8	high_impact	4,66	neutral	0,65	damaging	0,11	deleterious	3,29	22,8	0,26	0,55	disease	0,97	disease	0,92	disease	0,73	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,2	0,19	0,9	3,51	6,69	P	0,56	P	0,89	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12679	12679	A	C	MI.19970	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	343	115	N	H	Aat/Cat	-9,91	0	0	probably_damaging	0,98	neutral	0,54	neutral	1,44	neutral	-2,63	deleterious	-4,62	medium_impact	2,5	neutral	0,85	neutral	0,81	neutral	1,77	14,78	0,71	0,75	disease	0,77	disease	0,75	disease	0,55	disease	0,58	2	deleterious	0,98	neutral	0,28	deleterious	1	deleterious	0,79	low_impact	-2,35	medium_impact	0,27	medium_impact	1,08	0,46	0,8	17,91	16,66	N	0,24	N	0,36	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12680	12680	A	C	MI.19971	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	344	115	N	T	aAt/aCt	1,33	0	0	possibly_damaging	0,73	neutral	0,39	neutral	1,59	neutral	0,02	deleterious	-5,47	medium_impact	2,5	neutral	0,83	neutral	0,96	deleterious	3,31	22,9	0,65	0,7	disease	0,6	disease	0,65	neutral	0,36	neutral	0,49	0	neutral	0,74	neutral	0,33	NA	0	deleterious	0,74	low_impact	-1,16	medium_impact	0,13	medium_impact	1,08	0,46	0,8	17,91	16,66	N	0,32	N	0,65	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12680	12680	A	G	MI.19972	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	344	115	N	S	aAt/aGt	1,33	0	0	benign	0,18	neutral	0,45	neutral	1,6	neutral	0,13	deleterious	-4,48	medium_impact	2,48	neutral	0,87	neutral	0,93	deleterious	2,98	22,2	0,84	0,85	disease	0,6	disease	0,67	neutral	0,39	disease	0,51	0	neutral	0,46	deleterious	0,64	neutral	-3	deleterious	0,76	medium_impact	-0,12	medium_impact	0,18	medium_impact	1,06	0,2	0,8	17,91	16,66	N	0,34	N	0,65	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12680	12680	A	T	MI.19973	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	344	115	N	I	aAt/aTt	1,33	0	0	probably_damaging	0,96	neutral	0,43	neutral	1,48	neutral	-1,51	deleterious	-8,34	medium_impact	3,25	neutral	0,84	neutral	0,54	deleterious	3,79	23,4	0,42	0,55	disease	0,72	disease	0,9	disease	0,56	disease	0,66	3	neutral	0,96	neutral	0,24	deleterious	1	deleterious	0,82	low_impact	-2,06	medium_impact	0,17	medium_impact	1,77	0,31	0,8	17,91	16,66	N	0,35	N	0,93	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12681	12681	T	G	MI.19974	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	345	115	N	K	aaT/aaG	2,25	0,01	0,01	possibly_damaging	0,73	neutral	0,29	neutral	1,54	neutral	-0,47	deleterious	-5,49	medium_impact	2,1	neutral	0,74	neutral	0,52	deleterious	3,89	23,5	0,82	0,85	neutral	0,49	disease	0,84	disease	0,61	disease	0,56	1	neutral	0,79	neutral	0,28	NA	0	deleterious	0,77	low_impact	-1,16	medium_impact	0,02	medium_impact	0,72	0,54	0,8	17,91	16,66	N	0,35	N	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12681	12681	T	A	MI.19975	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	345	115	N	K	aaT/aaA	2,25	0,01	0,01	possibly_damaging	0,73	neutral	0,29	neutral	1,54	neutral	-0,47	deleterious	-5,49	medium_impact	2,1	neutral	0,74	neutral	0,52	deleterious	4,17	23,8	0,82	0,85	neutral	0,49	disease	0,84	disease	0,61	disease	0,56	1	neutral	0,79	neutral	0,28	NA	0	deleterious	0,77	low_impact	-1,16	medium_impact	0,02	medium_impact	0,72	0,54	0,8	17,91	16,66	N	0,34	N	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12682	12682	C	G	MI.19976	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	346	116	Q	E	Cag/Gag	-3,49	0	0	probably_damaging	1	neutral	0,28	neutral	1,57	neutral	-0,26	neutral	-1,12	medium_impact	2,77	neutral	0,69	damaging	0,19	deleterious	3	22,2	0,69	0,75	neutral	0,33	disease	0,62	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,01	medium_impact	1,33	0,54	0,8	10,61	12,78	N	0,33	N	0,45	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12682	12682	C	A	MI.19977	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	346	116	Q	K	Cag/Aag	-3,49	0	0	probably_damaging	1	neutral	0,3	neutral	1,66	neutral	0,9	neutral	0,61	neutral_impact	0,19	neutral	0,81	neutral	0,92	deleterious	2,59	20,1	0,65	0,7	neutral	0,37	neutral	0,43	neutral	0,39	neutral	0,45	1	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,03	low_impact	-1,03	0,5	0,8	10,61	12,78	N	0,35	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12683	12683	A	T	MI.19978	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	347	116	Q	L	cAg/cTg	0,87	0	0	probably_damaging	1	neutral	0,66	neutral	1,52	neutral	-1,63	deleterious	-3,36	low_impact	1,41	neutral	0,81	neutral	0,41	deleterious	3,65	23,2	0,53	0,6	neutral	0,47	disease	0,7	neutral	0,43	disease	0,52	0	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,39	medium_impact	0,09	0,18	0,8	10,61	12,78	N	0,19	N	0,79	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12683	12683	A	G	MI.19979	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	347	116	Q	R	cAg/cGg	0,87	0	0	probably_damaging	1	neutral	0,35	neutral	2,25	neutral	3,4	neutral	1,6	neutral_impact	-0,86	neutral	0,8	neutral	0,94	deleterious	0,68	8,69	0,7	0,75	neutral	0,43	neutral	0,15	neutral	0,37	neutral	0,24	5	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,08	low_impact	-1,99	0,47	0,8	10,61	12,78	N	0,33	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5959	5959	A	T	MI.1998	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	56	19	Y	F	tAc/tTc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,18	deleterious	-3,06	neutral	-1,69	high_impact	4,11	damaging	0,52	damaging	0,15	deleterious	3,19	22,7	0,26	0,55	disease	0,63	disease	0,87	disease	0,62	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,7	0,38	0,9	3,51	6,69	P	0,56	P	0,5	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12683	12683	A	C	MI.19980	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	347	116	Q	P	cAg/cCg	0,87	0	0	probably_damaging	1	neutral	0,21	neutral	1,51	neutral	-2,32	deleterious	-3,2	medium_impact	2,77	damaging	0,59	damaging	0,13	deleterious	3,24	22,8	0,4	0,5	disease	0,63	disease	0,86	disease	0,72	disease	0,81	6	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	-0,09	medium_impact	1,33	0,42	0,8	10,61	12,78	N	0,26	N	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12684	12684	G	C	MI.19981	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	348	116	Q	H	caG/caC	-0,27	0	0,01	probably_damaging	1	neutral	0,54	neutral	1,55	neutral	-0,86	neutral	-1,75	medium_impact	2,07	neutral	0,77	neutral	0,78	deleterious	3,42	23	0,72	0,75	disease	0,74	disease	0,51	disease	0,57	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,27	medium_impact	0,69	0,7	0,85	10,61	12,78	N	0,25	N	0,51	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12684	12684	G	T	MI.19982	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	348	116	Q	H	caG/caT	-0,27	0	0,01	probably_damaging	1	neutral	0,54	neutral	1,55	neutral	-0,86	neutral	-1,75	medium_impact	2,07	neutral	0,77	neutral	0,78	deleterious	3,48	23,1	0,72	0,75	disease	0,74	disease	0,51	disease	0,57	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,27	medium_impact	0,69	0,7	0,85	10,61	12,78	N	0,25	N	0,51	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12685	12685	T	G	MI.19983	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	349	117	F	V	Ttc/Gtc	-0,96	0	0	probably_damaging	1	neutral	0,52	neutral	-0,13	deleterious	-7,35	deleterious	-6,9	high_impact	4,42	damaging	0,4	damaging	0,05	deleterious	4,06	23,7	0,24	0,45	disease	0,78	disease	0,86	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,25	high_impact	2,83	0,56	0,8	27,53	7,12	P	0,51	P	0,95	polymorphism	0,98	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12685	12685	T	C	MI.19984	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	349	117	F	L	Ttc/Ctc	-0,96	0	0	probably_damaging	1	neutral	0,78	neutral	-0,03	deleterious	-4,73	deleterious	-5,92	high_impact	4,42	damaging	0,4	damaging	0,04	deleterious	4,08	23,7	0,4	0,5	disease	0,73	disease	0,81	disease	0,74	disease	0,75	5	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,54	high_impact	2,83	0,8	0,85	27,53	7,12	N	0,5	N	0,92	polymorphism	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12685	12685	T	A	MI.19985	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	349	117	F	I	Ttc/Atc	-0,96	0	0	probably_damaging	1	neutral	0,41	neutral	-0,13	deleterious	-7,35	deleterious	-5,92	high_impact	4,42	damaging	0,42	damaging	0,07	deleterious	4,47	24,2	0,2	0,45	disease	0,81	disease	0,85	disease	0,76	disease	0,8	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,15	high_impact	2,83	0,58	0,8	27,53	7,12	N	0,49	N	0,95	polymorphism	0,99	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12686	12686	T	A	MI.19986	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	350	117	F	Y	tTc/tAc	7,3	1	0	probably_damaging	1	neutral	1	neutral	-0,05	deleterious	-5	deleterious	-2,96	high_impact	3,73	damaging	0,4	damaging	0,05	deleterious	4,2	23,9	0,18	0,45	disease	0,62	disease	0,78	disease	0,71	disease	0,72	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,81	low_impact	-3,6	high_impact	1,89	high_impact	2,2	0,67	0,85	27,53	7,12	P	0,62	P	0,88	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12686	12686	T	C	MI.19987	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	350	117	F	S	tTc/tCc	7,3	1	0	probably_damaging	1	neutral	0,4	neutral	-0,14	deleterious	-8,18	deleterious	-7,89	high_impact	4,42	damaging	0,44	damaging	0,07	deleterious	4,13	23,8	0,17	0,45	disease	0,8	disease	0,84	disease	0,75	disease	0,79	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,14	high_impact	2,83	0,41	0,8	27,53	7,12	P	0,6	P	0,97	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12686	12686	T	G	MI.19988	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	350	117	F	C	tTc/tGc	7,3	1	0	probably_damaging	1	neutral	0,17	neutral	-0,15	deleterious	-9,66	deleterious	-7,89	high_impact	4,42	damaging	0,45	damaging	0,04	deleterious	4,01	23,6	0,18	0,45	disease	0,9	disease	0,86	disease	0,78	disease	0,84	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,15	high_impact	2,83	0,35	0,8	27,53	7,12	P	0,55	P	0,99	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12687	12687	C	G	MI.19989	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	351	117	F	L	ttC/ttG	5,69	1	0	probably_damaging	1	neutral	0,78	neutral	-0,03	deleterious	-4,73	deleterious	-5,92	high_impact	4,42	damaging	0,4	damaging	0,04	deleterious	4,26	23,9	0,4	0,5	disease	0,73	disease	0,81	disease	0,74	disease	0,75	5	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,54	high_impact	2,83	0,8	0,85	27,53	7,12	P	0,68	P	0,92	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5959	5959	A	C	MI.1999	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	56	19	Y	S	tAc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	1,98	deleterious	-7,01	deleterious	-3,8	high_impact	4,3	neutral	0,75	damaging	0,14	deleterious	3,51	23,1	0,21	0,55	disease	0,92	disease	0,9	disease	0,68	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	2,87	0,23	0,9	3,51	6,69	N	0,52	P	0,9	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12687	12687	C	A	MI.19990	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	351	117	F	L	ttC/ttA	5,69	1	0	probably_damaging	1	neutral	0,78	neutral	-0,03	deleterious	-4,73	deleterious	-5,92	high_impact	4,42	damaging	0,4	damaging	0,04	deleterious	4,55	24,4	0,4	0,5	disease	0,73	disease	0,81	disease	0,74	disease	0,75	5	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,54	high_impact	2,83	0,8	0,85	27,53	7,12	P	0,68	P	0,92	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12688	12688	T	A	MI.19991	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	352	118	F	I	Ttc/Atc	-2,11	0	0	possibly_damaging	0,53	neutral	0,42	neutral	1,31	neutral	-2,88	deleterious	-4,07	low_impact	1,16	neutral	0,81	neutral	0,8	neutral	1,48	13,19	0,26	0,45	disease	0,76	disease	0,73	disease	0,58	disease	0,58	2	neutral	0,58	neutral	0,45	neutral	-3	deleterious	0,53	medium_impact	-0,8	medium_impact	0,16	medium_impact	-0,14	0,68	0,85	18,57	17,25	N	0,26	N	0,29	polymorphism	0,52	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12688	12688	T	G	MI.19992	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	352	118	F	V	Ttc/Gtc	-2,11	0	0	possibly_damaging	0,53	neutral	0,54	neutral	1,22	neutral	-2,83	deleterious	-5	medium_impact	3,38	neutral	0,76	neutral	0,5	deleterious	2,28	18,04	0,28	0,45	disease	0,82	disease	0,85	disease	0,67	disease	0,74	5	neutral	0,5	deleterious	0,51	NA	0	deleterious	0,55	medium_impact	-0,8	medium_impact	0,27	medium_impact	1,88	0,7	0,85	18,57	17,25	N	0,27	N	0,71	disease_causing	0,66	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12688	12688	T	C	MI.19993	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	352	118	F	L	Ttc/Ctc	-2,11	0	0	benign	0,03	neutral	0,77	neutral	1,27	neutral	-2,12	deleterious	-3,95	medium_impact	2,02	neutral	0,79	neutral	0,68	deleterious	0,84	9,7	0,46	0,55	disease	0,72	disease	0,78	disease	0,57	disease	0,56	1	neutral	0,17	deleterious	0,87	neutral	-3	neutral	0,25	medium_impact	0,69	medium_impact	0,52	medium_impact	0,64	0,78	0,85	18,57	17,25	N	0,19	N	0,15	disease_causing	0,5	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12689	12689	T	A	MI.19994	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	353	118	F	Y	tTc/tAc	2,94	0,99	0	possibly_damaging	0,83	neutral	1	neutral	1,19	neutral	-0,48	deleterious	-2,52	medium_impact	2,96	neutral	0,79	neutral	0,56	deleterious	3,87	23,5	0,37	0,5	disease	0,52	disease	0,77	disease	0,58	disease	0,62	2	neutral	0,83	deleterious	0,59	NA	0	deleterious	0,67	low_impact	-1,4	high_impact	1,89	medium_impact	1,5	0,73	0,85	18,57	17,25	N	0,38	N	0,71	polymorphism	0,95	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12689	12689	T	C	MI.19995	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	353	118	F	S	tTc/tCc	2,94	0,99	0	possibly_damaging	0,89	neutral	0,47	neutral	1,15	deleterious	-4,1	deleterious	-6,52	medium_impact	2,58	neutral	0,72	neutral	0,65	deleterious	3,99	23,6	0,28	0,45	disease	0,71	disease	0,82	disease	0,62	disease	0,59	2	neutral	0,89	neutral	0,29	NA	0	deleterious	0,75	low_impact	-1,61	medium_impact	0,2	medium_impact	1,15	0,58	0,8	18,57	17,25	N	0,46	N	0,89	polymorphism	0,69	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12689	12689	T	G	MI.19996	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	353	118	F	C	tTc/tGc	2,94	0,99	0	probably_damaging	0,98	neutral	0,17	neutral	1,13	deleterious	-5,34	deleterious	-6,35	medium_impact	3,04	neutral	0,76	neutral	0,48	deleterious	3,95	23,6	0,27	0,45	disease	0,96	disease	0,87	disease	0,69	disease	0,81	6	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,82	low_impact	-2,35	medium_impact	-0,15	medium_impact	1,57	0,42	0,8	18,57	17,25	N	0,37	N	0,78	polymorphism	0,59	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12690	12690	C	A	MI.19997	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	354	118	F	L	ttC/ttA	4,31	0,99	0	benign	0,03	neutral	0,77	neutral	1,27	neutral	-2,12	deleterious	-3,95	medium_impact	2,02	neutral	0,79	neutral	0,68	neutral	1,53	13,47	0,46	0,55	disease	0,72	disease	0,78	disease	0,57	disease	0,56	1	neutral	0,17	deleterious	0,87	neutral	-3	neutral	0,25	medium_impact	0,69	medium_impact	0,52	medium_impact	0,64	0,78	0,85	18,57	17,25	N	0,43	N	0,15	polymorphism	0,56	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12690	12690	C	G	MI.19998	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	354	118	F	L	ttC/ttG	4,31	0,99	0	benign	0,03	neutral	0,77	neutral	1,27	neutral	-2,12	deleterious	-3,95	medium_impact	2,02	neutral	0,79	neutral	0,68	neutral	1,21	11,82	0,46	0,55	disease	0,72	disease	0,78	disease	0,57	disease	0,56	1	neutral	0,17	deleterious	0,87	neutral	-3	neutral	0,25	medium_impact	0,69	medium_impact	0,52	medium_impact	0,64	0,78	0,85	18,57	17,25	N	0,42	N	0,15	polymorphism	0,56	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12691	12691	A	G	MI.19999	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	355	119	K	E	Aaa/Gaa	-4,63	0	0	probably_damaging	1	neutral	0,26	neutral	1,48	neutral	-0,38	deleterious	-3,81	high_impact	4,24	neutral	0,69	damaging	0,15	deleterious	3,89	23,5	0,42	0,55	disease	0,64	disease	0,85	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	-0,02	high_impact	2,67	0,64	0,8	24,71	7,09	N	0,38	N	0,84	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8527	8527	A	T	MI.2	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	1	1	M	L	Atg/Ttg	2,21	1	0	possibly_damaging	0,52	deleterious	0,02	neutral	4,7	neutral	0,88	neutral	-2,48	NA	NA	neutral	0,63	damaging	0,08	deleterious	3,94	23,6	0,38	0,65	disease	0,68	neutral	0,34	disease	0,63	disease	0,57	1	neutral	0,98	neutral	0,25	deleterious	3	deleterious	0,51	NA	NA	NA	NA	NA	NA	0,5	0,9	50	8,74	P	0,5	N	0,93	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8535	8535	A	T	MI.20	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	9	3	E	D	gaA/gaT	4,06	1	0	probably_damaging	0,95	neutral	0,24	neutral	4,64	neutral	-0,82	neutral	-1,77	low_impact	1,61	neutral	0,84	neutral	0,46	deleterious	4,02	23,6	0,62	0,7	disease	0,61	neutral	0,13	neutral	0,18	neutral	0,41	2	neutral	0,96	neutral	0,15	neutral	-2	deleterious	0,64	low_impact	-1,97	medium_impact	0,01	medium_impact	0,28	0,92	0,95	15,93	14,48	P	0,56	P	0,87	polymorphism	0,9	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8620	8620	C	T	MI.200	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	94	32	P	S	Ccc/Tcc	-6,35	0	0	probably_damaging	1	neutral	0,23	neutral	4,45	neutral	1,75	deleterious	-5,83	medium_impact	2,06	neutral	0,93	neutral	0,76	deleterious	3,66	23,2	0,53	0,65	neutral	0,47	disease	0,72	neutral	0,36	disease	0,52	0	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,01	medium_impact	0,67	0,12	0,9	29,2	19,38	N	0,39	N	0,27	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5961	5961	C	A	MI.2000	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	58	20	L	M	Cta/Ata	-2,42	0	0	probably_damaging	1	neutral	0,08	neutral	2,59	neutral	-2,07	neutral	-0,29	low_impact	1,7	neutral	0,72	neutral	0,84	neutral	0,93	10,25	0,19	0,55	disease	0,65	disease	0,61	neutral	0,28	neutral	0,5	0	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,78	low_impact	-3,58	medium_impact	-0,4	medium_impact	0,47	0,57	0,9	10,14	14,27	N	0,44	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12691	12691	A	C	MI.20000	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	355	119	K	Q	Aaa/Caa	-4,63	0	0	probably_damaging	1	neutral	0,28	neutral	1,47	neutral	-0,78	deleterious	-3,73	high_impact	3,68	neutral	0,77	damaging	0,18	deleterious	3,33	22,9	0,5	0,6	neutral	0,49	disease	0,75	disease	0,53	disease	0,61	2	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,74	low_impact	-3,6	medium_impact	0,01	high_impact	2,16	0,6	0,8	24,71	7,09	N	0,29	N	0,82	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12692	12692	A	T	MI.20001	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	356	119	K	M	aAa/aTa	4,54	0,99	0	probably_damaging	1	neutral	0,31	neutral	1,45	neutral	-0,35	deleterious	-5,39	medium_impact	3,19	neutral	0,8	damaging	0,16	deleterious	3,85	23,4	0,32	0,5	disease	0,64	disease	0,74	disease	0,52	disease	0,55	1	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,04	medium_impact	1,71	0,54	0,8	24,71	7,09	N	0,43	N	0,4	polymorphism	0,54	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12692	12692	A	C	MI.20002	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	356	119	K	T	aAa/aCa	4,54	0,99	0	probably_damaging	1	neutral	0,38	neutral	1,5	neutral	0,8	deleterious	-5,63	high_impact	3,68	neutral	0,71	damaging	0,25	deleterious	3,59	23,2	0,31	0,45	disease	0,64	disease	0,74	disease	0,54	disease	0,54	1	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,12	high_impact	2,16	0,43	0,8	24,71	7,09	N	0,46	N	0,75	polymorphism	0,73	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12693	12693	A	C	MI.20003	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	357	119	K	N	aaA/aaC	4,54	0,99	0	probably_damaging	1	neutral	0,31	neutral	1,46	neutral	-1,24	deleterious	-4,75	medium_impact	2,56	neutral	0,73	damaging	0,19	deleterious	3,62	23,2	0,55	0,6	disease	0,69	disease	0,75	disease	0,54	disease	0,58	1	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,04	medium_impact	1,14	0,63	0,8	24,71	7,09	N	0,46	N	0,63	polymorphism	0,6	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12693	12693	A	T	MI.20004	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	357	119	K	N	aaA/aaT	4,54	0,99	0	probably_damaging	1	neutral	0,31	neutral	1,46	neutral	-1,24	deleterious	-4,75	medium_impact	2,56	neutral	0,73	damaging	0,19	deleterious	3,73	23,3	0,55	0,6	disease	0,69	disease	0,75	disease	0,54	disease	0,58	1	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,04	medium_impact	1,14	0,63	0,8	24,71	7,09	N	0,47	N	0,63	polymorphism	0,6	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12694	12694	T	C	MI.20005	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	358	120	Y	H	Tat/Cat	-0,27	0,43	0	probably_damaging	0,98	neutral	0,48	neutral	0,91	deleterious	-5,93	deleterious	-4,93	medium_impact	2,94	neutral	0,62	neutral	0,68	deleterious	3,53	23,1	0,32	0,5	disease	0,94	disease	0,84	disease	0,7	disease	0,79	6	neutral	0,98	neutral	0,25	deleterious	1	deleterious	0,83	low_impact	-2,35	medium_impact	0,21	medium_impact	1,48	0,57	0,8	17,74	7,05	N	0,3	N	0,88	disease_causing	0,88	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12694	12694	T	A	MI.20006	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	358	120	Y	N	Tat/Aat	-0,27	0,43	0	probably_damaging	0,98	neutral	0,35	neutral	0,91	deleterious	-5,84	deleterious	-8,88	high_impact	4,29	neutral	0,67	neutral	0,44	deleterious	4,09	23,7	0,29	0,45	disease	0,94	disease	0,89	disease	0,64	disease	0,81	6	neutral	0,98	neutral	0,19	deleterious	2	deleterious	0,83	low_impact	-2,35	medium_impact	0,08	high_impact	2,72	0,43	0,8	17,74	7,05	N	0,42	N	0,92	disease_causing	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12694	12694	T	G	MI.20007	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	358	120	Y	D	Tat/Gat	-0,27	0,43	0	probably_damaging	0,98	neutral	0,2	neutral	0,91	deleterious	-6,57	deleterious	-9,86	high_impact	4,29	neutral	0,69	neutral	0,38	deleterious	3,79	23,4	0,19	0,45	disease	0,96	disease	0,89	disease	0,76	disease	0,85	7	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,83	low_impact	-2,35	medium_impact	-0,1	high_impact	2,72	0,42	0,8	17,74	7,05	N	0,46	N	0,94	disease_causing	0,98	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12695	12695	A	T	MI.20008	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	359	120	Y	F	tAt/tTt	4,54	1	0	benign	0,12	neutral	0,73	neutral	0,95	deleterious	-4,06	deleterious	-3,94	medium_impact	3,01	neutral	0,72	neutral	0,66	neutral	1,18	11,64	0,32	0,5	disease	0,62	disease	0,81	disease	0,59	disease	0,52	0	neutral	0,16	deleterious	0,81	neutral	-3	neutral	0,29	medium_impact	0,08	medium_impact	0,47	medium_impact	1,55	0,65	0,8	17,74	7,05	N	0,45	N	0,26	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12695	12695	A	G	MI.20009	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	359	120	Y	C	tAt/tGt	4,54	1	0	probably_damaging	0,98	neutral	0,15	neutral	0,91	deleterious	-6,16	deleterious	-8,88	high_impact	4,29	neutral	0,67	neutral	0,31	deleterious	3,31	22,9	0,3	0,45	disease	0,94	disease	0,89	disease	0,72	disease	0,83	7	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-2,35	medium_impact	-0,18	high_impact	2,72	0,34	0,8	17,74	7,05	N	0,48	N	0,97	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5961	5961	C	G	MI.2001	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	58	20	L	V	Cta/Gta	-2,42	0	0	probably_damaging	0,99	deleterious	0,01	neutral	2,73	neutral	-0,51	neutral	-0,71	medium_impact	2,77	neutral	0,62	neutral	0,45	neutral	1,52	13,43	0,17	0,55	disease	0,51	disease	0,73	disease	0,51	disease	0,58	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-2,64	medium_impact	-0,92	medium_impact	1,46	0,55	0,9	10,14	14,27	N	0,36	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12695	12695	A	C	MI.20010	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	359	120	Y	S	tAt/tCt	4,54	1	0	probably_damaging	0,97	neutral	0,38	neutral	0,93	deleterious	-4,78	deleterious	-8,88	high_impact	3,94	neutral	0,69	neutral	0,48	deleterious	3,35	22,9	0,28	0,45	disease	0,85	disease	0,86	disease	0,68	disease	0,78	6	neutral	0,97	neutral	0,21	deleterious	2	deleterious	0,79	low_impact	-2,18	medium_impact	0,12	high_impact	2,4	0,54	0,8	17,74	7,05	N	0,51	P	0,93	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12697	12697	C	A	MI.20011	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	361	121	L	M	Cta/Ata	-4,86	0	0	probably_damaging	1	neutral	0,24	neutral	0,86	deleterious	-3,29	neutral	-1,91	medium_impact	3,5	damaging	0,51	damaging	0,14	deleterious	3,74	23,3	0,3	0,45	disease	0,73	disease	0,6	disease	0,51	disease	0,53	1	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	-0,04	medium_impact	1,99	0,7	0,85	28,03	7,23	N	0,37	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12697	12697	C	G	MI.20012	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	361	121	L	V	Cta/Gta	-4,86	0	0	probably_damaging	1	neutral	0,52	neutral	0,88	deleterious	-3,08	deleterious	-2,91	medium_impact	3,36	damaging	0,43	damaging	0,1	deleterious	3,24	22,8	0,23	0,45	disease	0,73	disease	0,62	disease	0,65	disease	0,59	2	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,25	medium_impact	1,87	0,57	0,8	28,03	7,23	N	0,33	N	0,81	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12698	12698	T	A	MI.20013	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	362	121	L	Q	cTa/cAa	-0,73	0	0	probably_damaging	1	neutral	0,29	neutral	0,76	deleterious	-6,03	deleterious	-5,7	high_impact	4,39	damaging	0,45	damaging	0,1	deleterious	3,86	23,5	0,13	0,4	disease	0,92	disease	0,79	disease	0,67	disease	0,8	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,02	high_impact	2,81	0,69	0,85	28,03	7,23	N	0,39	N	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12698	12698	T	G	MI.20014	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	362	121	L	R	cTa/cGa	-0,73	0	0	probably_damaging	1	neutral	0,43	neutral	0,76	deleterious	-5,9	deleterious	-5,77	high_impact	4,39	damaging	0,53	damaging	0,08	deleterious	3,97	23,6	0,11	0,4	disease	0,94	disease	0,91	disease	0,77	disease	0,85	7	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,17	high_impact	2,81	0,48	0,8	28,03	7,23	N	0,43	N	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12698	12698	T	C	MI.20015	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	362	121	L	P	cTa/cCa	-0,73	0	0	probably_damaging	1	neutral	0,19	neutral	0,76	deleterious	-6,48	deleterious	-6,77	high_impact	4,39	damaging	0,46	damaging	0,09	deleterious	3,73	23,3	0,11	0,4	disease	0,96	disease	0,81	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,12	high_impact	2,81	0,66	0,8	28,03	7,23	N	0,42	N	0,99	polymorphism	0,78	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12700	12700	C	T	MI.20016	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	364	122	L	F	Ctc/Ttc	-9,91	0	0	probably_damaging	1	neutral	0,76	neutral	1,44	deleterious	-3,04	deleterious	-3,87	medium_impact	3	neutral	0,68	damaging	0,09	deleterious	3,87	23,5	0,35	0,5	disease	0,9	disease	0,74	disease	0,62	disease	0,76	5	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,51	medium_impact	1,54	0,73	0,85	19,57	16,92	N	0,17	N	0,52	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12700	12700	C	A	MI.20017	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	364	122	L	I	Ctc/Atc	-9,91	0	0	probably_damaging	1	neutral	0,27	neutral	1,56	deleterious	-3,02	neutral	-1,83	low_impact	1,78	neutral	0,79	neutral	0,67	deleterious	2,86	21,7	0,34	0,5	disease	0,74	disease	0,61	disease	0,53	disease	0,52	0	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	-0,01	medium_impact	0,42	0,81	0,85	19,57	16,92	N	0,31	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12700	12700	C	G	MI.20018	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	364	122	L	V	Ctc/Gtc	-9,91	0	0	probably_damaging	1	neutral	0,24	neutral	1,48	neutral	-2,54	deleterious	-2,81	medium_impact	2,9	neutral	0,7	damaging	0,09	deleterious	3,28	22,8	0,37	0,5	disease	0,8	disease	0,61	disease	0,55	disease	0,61	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	-0,04	medium_impact	1,45	0,68	0,85	19,57	16,92	N	0,24	N	0,16	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12701	12701	T	C	MI.20019	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	365	122	L	P	cTc/cCc	-0,27	0	0	probably_damaging	1	neutral	0,09	neutral	1,43	deleterious	-4,7	deleterious	-6,82	high_impact	4,04	neutral	0,63	damaging	0,09	deleterious	3,84	23,4	0,06	0,35	disease	0,9	disease	0,86	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,32	high_impact	2,49	0,66	0,8	19,57	16,92	N	0,32	N	0,93	disease_causing	0,6	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5962	5962	T	C	MI.2002	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	59	20	L	P	cTa/cCa	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-4,51	neutral	-2,2	high_impact	3,82	damaging	0,6	neutral	0,33	deleterious	3,73	23,3	0,11	0,55	disease	0,89	disease	0,94	disease	0,64	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,93	low_impact	-3,58	low_impact	-1,48	high_impact	2,43	0,49	0,9	10,14	14,27	N	0,3	N	0,83	polymorphism	0,9	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12701	12701	T	G	MI.20020	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	365	122	L	R	cTc/cGc	-0,27	0	0	probably_damaging	1	neutral	0,14	neutral	1,45	deleterious	-5,44	deleterious	-5,86	high_impact	4,04	neutral	0,64	damaging	0,09	deleterious	4,05	23,7	0,08	0,35	disease	0,9	disease	0,92	disease	0,73	disease	0,83	7	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,2	high_impact	2,49	0,62	0,8	19,57	16,92	N	0,31	N	0,91	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12701	12701	T	A	MI.20021	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	365	122	L	H	cTc/cAc	-0,27	0	0	probably_damaging	1	neutral	0,21	neutral	1,43	deleterious	-4,72	deleterious	-6,82	high_impact	4,04	neutral	0,68	damaging	0,09	deleterious	4,13	23,8	0,09	0,35	disease	0,9	disease	0,82	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,09	high_impact	2,49	0,71	0,85	19,57	16,92	N	0,31	N	0,82	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12703	12703	A	T	MI.20022	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	367	123	I	F	Atc/Ttc	-12,66	0	0	possibly_damaging	0,88	neutral	0,67	neutral	1,52	neutral	0,11	neutral	-1,69	low_impact	1,9	neutral	0,8	neutral	0,79	deleterious	3,63	23,2	0,38	0,5	disease	0,51	disease	0,7	disease	0,59	disease	0,68	4	neutral	0,86	neutral	0,4	neutral	-3	deleterious	0,73	low_impact	-1,57	medium_impact	0,4	medium_impact	0,53	0,72	0,85	22,22	17,52	N	0,2	N	0,37	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12703	12703	A	G	MI.20023	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	367	123	I	V	Atc/Gtc	-12,66	0	0	benign	0,09	neutral	0,53	neutral	1,52	neutral	-0,38	neutral	-0,56	low_impact	1,81	neutral	0,75	neutral	0,77	neutral	1,77	14,8	0,49	0,55	disease	0,6	neutral	0,28	neutral	0,37	disease	0,55	1	neutral	0,39	deleterious	0,72	neutral	-6	deleterious	0,66	medium_impact	0,21	medium_impact	0,26	medium_impact	0,45	0,52	0,8	22,22	17,52	N	0,31	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12703	12703	A	C	MI.20024	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	367	123	I	L	Atc/Ctc	-12,66	0	0	benign	0,3	neutral	1	neutral	1,7	neutral	2,12	neutral	0,9	neutral_impact	0,16	neutral	0,81	neutral	0,97	neutral	0,94	10,3	0,28	0,45	neutral	0,36	neutral	0,25	neutral	0,28	neutral	0,46	1	neutral	0,3	deleterious	0,85	neutral	-6	deleterious	0,62	medium_impact	-0,4	high_impact	1,89	low_impact	-1,06	0,65	0,8	22,22	17,52	N	0,31	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12704	12704	T	C	MI.20025	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	368	123	I	T	aTc/aCc	-2,8	0	0	benign	0,09	neutral	0,27	neutral	1,51	neutral	-1,69	neutral	-2,21	low_impact	0,9	neutral	0,86	neutral	0,98	neutral	1,69	14,35	0,39	0,5	disease	0,64	neutral	0,28	neutral	0,37	disease	0,56	1	neutral	0,7	deleterious	0,59	neutral	-6	deleterious	0,7	medium_impact	0,21	medium_impact	-0,01	medium_impact	-0,38	0,66	0,8	22,22	17,52	N	0,36	N	0,3	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12704	12704	T	G	MI.20026	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	368	123	I	S	aTc/aGc	-2,8	0	0	possibly_damaging	0,66	neutral	0,22	neutral	1,46	neutral	-2,41	deleterious	-3,19	medium_impact	2,88	neutral	0,85	neutral	0,6	deleterious	4,15	23,8	0,3	0,45	disease	0,76	disease	0,71	disease	0,55	disease	0,68	4	neutral	0,81	neutral	0,28	NA	0	deleterious	0,75	low_impact	-1,02	medium_impact	-0,07	medium_impact	1,43	0,55	0,8	22,22	17,52	N	0,31	N	0,39	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12704	12704	T	A	MI.20027	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	368	123	I	N	aTc/aAc	-2,8	0	0	probably_damaging	0,91	neutral	0,14	neutral	1,4	deleterious	-3,83	deleterious	-4,18	medium_impact	3,23	neutral	0,73	neutral	0,38	deleterious	4,3	24	0,26	0,45	disease	0,91	disease	0,76	disease	0,59	disease	0,78	6	neutral	0,96	neutral	0,12	deleterious	1	deleterious	0,8	low_impact	-1,7	medium_impact	-0,2	medium_impact	1,75	0,71	0,85	22,22	17,52	N	0,32	N	0,79	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12705	12705	C	A	MI.20028	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	369	123	I	M	atC/atA	-0,27	0	0,88	benign	0,41	neutral	0,13	neutral	1,48	neutral	-0,98	neutral	0,5	neutral_impact	0,58	neutral	0,84	neutral	0,98	neutral	1,64	14,09	0,39	0,5	disease	0,5	neutral	0,23	neutral	0,3	neutral	0,2	6	neutral	0,85	neutral	0,36	neutral	-6	deleterious	0,67	medium_impact	-0,6	medium_impact	-0,22	medium_impact	-0,67	0,82	0,85	22,22	17,52	N	0,44	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12705	12705	C	G	MI.20029	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	369	123	I	M	atC/atG	-0,27	0	0,88	benign	0,41	neutral	0,13	neutral	1,48	neutral	-0,98	neutral	0,5	neutral_impact	0,58	neutral	0,84	neutral	0,98	neutral	1,21	11,81	0,39	0,5	disease	0,5	neutral	0,23	neutral	0,3	neutral	0,2	6	neutral	0,85	neutral	0,36	neutral	-6	deleterious	0,67	medium_impact	-0,6	medium_impact	-0,22	medium_impact	-0,67	0,82	0,85	22,22	17,52	N	0,44	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5962	5962	T	A	MI.2003	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	59	20	L	Q	cTa/cAa	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-4,11	neutral	-1,77	high_impact	3,82	neutral	0,67	neutral	0,41	deleterious	3,87	23,5	0,14	0,55	disease	0,85	disease	0,86	disease	0,52	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,43	0,65	0,9	10,14	14,27	N	0,35	N	0,82	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12706	12706	T	C	MI.20030	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	370	124	F	L	Ttc/Ctc	-5,55	0	0	probably_damaging	1	neutral	1	neutral	3,25	neutral	-2,08	deleterious	-5,92	high_impact	5	damaging	0,07	neutral	0,5	deleterious	3,92	23,5	0,35	0,5	disease	0,64	disease	0,86	disease	0,66	disease	0,72	4	deleterious	0,99	deleterious	0,5	deleterious	2	deleterious	0,78	low_impact	-3,6	high_impact	1,89	high_impact	3,36	0,56	0,8	27,86	7,15	P	0,9	P	0,91	disease_causing_automatic	0,02	0,27	rs267606893	Pathogenic|Pathogenic	Leigh_syndrome_due_to_mitochondrial_complex_I_deficiency|Leigh_syndrome	RCV000010338.2|RCV000144015.2	MedGen|MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	T12706C	Leigh Disease	-	+	Cfrm	7
chrM	12706	12706	T	G	MI.20031	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	370	124	F	V	Ttc/Gtc	-5,55	0	0	probably_damaging	1	neutral	0,61	neutral	3,14	deleterious	-3,6	deleterious	-6,9	high_impact	5	damaging	0,21	neutral	0,43	deleterious	3,93	23,5	0,28	0,45	disease	0,68	disease	0,89	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,34	high_impact	3,36	0,63	0,8	27,86	7,15	P	0,87	P	0,94	polymorphism	0,95	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12706	12706	T	A	MI.20032	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	370	124	F	I	Ttc/Atc	-5,55	0	0	probably_damaging	1	neutral	0,56	neutral	3,13	deleterious	-3,75	deleterious	-5,92	high_impact	5	damaging	0,29	neutral	0,58	deleterious	4,25	23,9	0,19	0,45	disease	0,78	disease	0,87	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,29	high_impact	3,36	0,56	0,8	27,86	7,15	P	0,87	P	0,95	polymorphism	0,98	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12707	12707	T	G	MI.20033	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	371	124	F	C	tTc/tGc	5,69	1	0	probably_damaging	1	neutral	0,18	neutral	3,08	deleterious	-5,35	deleterious	-7,89	high_impact	5	damaging	0,29	neutral	0,45	deleterious	3,99	23,6	0,25	0,45	disease	0,9	disease	0,88	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,13	high_impact	3,36	0,42	0,8	27,86	7,15	P	0,9	P	0,99	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12707	12707	T	C	MI.20034	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	371	124	F	S	tTc/tCc	5,69	1	0	probably_damaging	1	neutral	0,55	neutral	3,15	deleterious	-3,67	deleterious	-7,89	high_impact	4,3	damaging	0,31	neutral	0,57	deleterious	4,13	23,8	0,26	0,45	disease	0,85	disease	0,86	disease	0,69	disease	0,78	6	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,28	high_impact	2,73	0,58	0,8	27,86	7,15	P	0,79	P	0,99	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12707	12707	T	A	MI.20035	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	371	124	F	Y	tTc/tAc	5,69	1	0	probably_damaging	1	neutral	0,83	neutral	3,09	deleterious	-5,25	deleterious	-2,96	high_impact	5	damaging	0,31	neutral	0,43	deleterious	4,13	23,8	0,21	0,45	disease	0,64	disease	0,83	disease	0,68	disease	0,7	4	deleterious	0,99	neutral	0,42	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,61	high_impact	3,36	0,59	0,8	27,86	7,15	P	0,84	P	0,88	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12708	12708	C	G	MI.20036	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	372	124	F	L	ttC/ttG	5,69	1	0	probably_damaging	1	neutral	1	neutral	3,25	neutral	-2,08	deleterious	-5,92	high_impact	5	damaging	0,07	neutral	0,5	deleterious	4,24	23,9	0,35	0,5	disease	0,64	disease	0,86	disease	0,66	disease	0,72	4	deleterious	0,99	deleterious	0,5	deleterious	2	deleterious	0,78	low_impact	-3,6	high_impact	1,89	high_impact	3,36	0,56	0,8	27,86	7,15	P	0,95	P	0,91	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12708	12708	C	A	MI.20037	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	372	124	F	L	ttC/ttA	5,69	1	0	probably_damaging	1	neutral	1	neutral	3,25	neutral	-2,08	deleterious	-5,92	high_impact	5	damaging	0,07	neutral	0,5	deleterious	4,57	24,4	0,35	0,5	disease	0,64	disease	0,86	disease	0,66	disease	0,72	4	deleterious	0,99	deleterious	0,5	deleterious	2	deleterious	0,78	low_impact	-3,6	high_impact	1,89	high_impact	3,36	0,56	0,8	27,86	7,15	P	0,95	P	0,91	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12709	12709	C	G	MI.20038	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	373	125	L	V	Cta/Gta	-1,65	0	0	probably_damaging	1	neutral	0,5	neutral	3,66	neutral	-0,71	deleterious	-2,96	low_impact	1,92	damaging	0,5	damaging	0,04	deleterious	3,27	22,8	0,6	0,65	disease	0,61	disease	0,7	disease	0,66	disease	0,62	2	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,77	low_impact	-3,6	medium_impact	0,23	medium_impact	0,55	0,5	0,8	28,69	7,2	N	0,22	N	0,78	polymorphism	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12709	12709	C	A	MI.20039	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	373	125	L	M	Cta/Ata	-1,65	0	0	probably_damaging	1	neutral	0,32	neutral	3,56	neutral	-1,54	neutral	-1,97	low_impact	1,72	damaging	0,56	damaging	0,06	deleterious	3,6	23,2	0,38	0,5	disease	0,59	disease	0,67	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	0,05	medium_impact	0,37	0,44	0,8	28,69	7,2	N	0,24	N	0,85	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5962	5962	T	G	MI.2004	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	59	20	L	R	cTa/cGa	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-3,94	neutral	-1,78	high_impact	3,82	neutral	0,61	neutral	0,29	deleterious	3,97	23,6	0,12	0,55	disease	0,85	disease	0,95	disease	0,64	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,93	low_impact	-3,58	low_impact	-1,48	high_impact	2,43	0,61	0,9	10,14	14,27	N	0,32	N	0,9	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12710	12710	T	G	MI.20040	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	374	125	L	R	cTa/cGa	-0,27	0	0	probably_damaging	1	neutral	0,13	neutral	3,47	deleterious	-4,74	deleterious	-5,92	high_impact	4,35	damaging	0,54	damaging	0,04	deleterious	4,02	23,6	0,21	0,45	disease	0,91	disease	0,94	disease	0,77	disease	0,88	8	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,22	high_impact	2,77	0,51	0,8	28,69	7,2	N	0,43	N	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12710	12710	T	C	MI.20041	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	374	125	L	P	cTa/cCa	-0,27	0	0	probably_damaging	1	neutral	0,08	neutral	3,47	deleterious	-5,39	deleterious	-6,91	high_impact	4,35	damaging	0,5	damaging	0,04	deleterious	3,78	23,4	0,17	0,45	disease	0,64	disease	0,88	disease	0,78	disease	0,81	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,35	high_impact	2,77	0,59	0,8	28,69	7,2	N	0,42	N	0,99	polymorphism	0,85	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12710	12710	T	A	MI.20042	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	374	125	L	Q	cTa/cAa	-0,27	0	0	probably_damaging	1	neutral	0,13	neutral	3,49	deleterious	-3,25	deleterious	-5,92	high_impact	4,35	damaging	0,48	damaging	0,03	deleterious	3,95	23,6	0,25	0,45	disease	0,84	disease	0,84	disease	0,67	disease	0,76	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,22	high_impact	2,77	0,59	0,8	28,69	7,2	N	0,38	N	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12712	12712	A	T	MI.20043	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	376	126	I	F	Att/Ttt	-7,84	0	0	benign	0,36	neutral	0,38	neutral	3,85	neutral	0,78	deleterious	-3,81	neutral_impact	0,56	neutral	0,81	neutral	0,71	neutral	0,9	10,07	0,55	0,6	neutral	0,38	disease	0,65	neutral	0,5	neutral	0,47	1	neutral	0,55	deleterious	0,51	neutral	-6	deleterious	0,5	medium_impact	-0,51	medium_impact	0,12	medium_impact	-0,69	0,7	0,85	20,07	17,52	N	0,27	N	0,72	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12712	12712	A	G	MI.20044	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	376	126	I	V	Att/Gtt	-7,84	0	0	benign	0,01	neutral	0,36	neutral	3,79	neutral	0,14	neutral	-0,89	low_impact	1,19	neutral	0,81	neutral	0,83	neutral	-0,59	0,13	0,71	0,75	disease	0,63	neutral	0,29	neutral	0,33	disease	0,56	1	neutral	0,63	deleterious	0,68	neutral	-6	neutral	0,2	medium_impact	1,15	medium_impact	0,1	medium_impact	-0,12	0,52	0,8	20,07	17,52	N	0,34	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12712	12712	A	C	MI.20045	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	376	126	I	L	Att/Ctt	-7,84	0	0	benign	0,05	neutral	1	neutral	3,9	neutral	0,85	neutral	-1,85	low_impact	0,99	neutral	0,8	neutral	0,75	deleterious	0,6	8,15	0,39	0,5	neutral	0,48	disease	0,59	neutral	0,34	neutral	0,47	1	neutral	0,05	deleterious	0,98	neutral	-6	neutral	0,19	medium_impact	0,47	high_impact	1,89	medium_impact	-0,3	0,59	0,8	20,07	17,52	N	0,2	N	0,35	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12713	12713	T	A	MI.20046	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	377	126	I	N	aTt/aAt	0,18	0	0	possibly_damaging	0,47	neutral	0,1	neutral	3,67	deleterious	-3,31	deleterious	-6,66	high_impact	3,62	neutral	0,82	neutral	0,37	deleterious	2,6	20,2	0,44	0,55	disease	0,86	disease	0,87	disease	0,6	disease	0,77	5	neutral	0,89	neutral	0,32	deleterious	1	deleterious	0,61	medium_impact	-0,7	medium_impact	-0,29	high_impact	2,1	0,54	0,8	20,07	17,52	N	0,36	N	0,98	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12713	12713	T	G	MI.20047	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	377	126	I	S	aTt/aGt	0,18	0	0	benign	0,19	neutral	0,31	neutral	3,75	neutral	-0,21	deleterious	-5,67	medium_impact	2,04	neutral	0,71	neutral	0,37	deleterious	2,25	17,87	0,46	0,55	disease	0,6	disease	0,84	disease	0,57	disease	0,72	4	neutral	0,63	deleterious	0,56	neutral	-3	neutral	0,36	medium_impact	-0,15	medium_impact	0,04	medium_impact	0,66	0,5	0,8	20,07	17,52	N	0,27	N	0,86	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12713	12713	T	C	MI.20048	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	377	126	I	T	aTt/aCt	0,18	0	0	benign	0,01	neutral	0,13	neutral	3,78	neutral	-0,07	deleterious	-4,67	low_impact	1,41	neutral	0,84	neutral	0,56	neutral	1,3	12,28	0,58	0,65	disease	0,59	disease	0,64	neutral	0,39	disease	0,52	0	neutral	0,87	deleterious	0,56	neutral	-6	neutral	0,22	medium_impact	1,15	medium_impact	-0,22	medium_impact	0,09	0,54	0,8	20,07	17,52	N	0,35	N	0,59	polymorphism	1	0,11	.	.	.	.	.	.	COSM1155527	.	.	.	.	.	.	.	.
chrM	12714	12714	T	G	MI.20049	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	378	126	I	M	atT/atG	3,63	0,36	0,01	benign	0,05	neutral	0,14	neutral	3,73	neutral	-0,95	deleterious	-2,67	neutral_impact	0,74	neutral	0,83	neutral	0,78	deleterious	2,91	21,9	0,58	0,65	disease	0,66	disease	0,56	neutral	0,32	neutral	0,49	0	neutral	0,85	deleterious	0,55	neutral	-6	deleterious	0,59	medium_impact	0,47	medium_impact	-0,2	medium_impact	-0,53	0,74	0,85	20,07	17,52	N	0,36	N	0,64	polymorphism	1	0,1	rs386829163	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5964	5964	T	G	MI.2005	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	61	21	L	V	Tta/Gta	-3,81	0	0,03	benign	0,09	neutral	0,54	neutral	2,8	neutral	1,18	neutral	-0,03	neutral_impact	0,24	neutral	0,71	neutral	0,53	deleterious	1,95	15,89	0,3	0,55	neutral	0,16	neutral	0,47	neutral	0,28	neutral	0,46	1	neutral	0,38	deleterious	0,73	neutral	-6	neutral	0,2	medium_impact	0,19	medium_impact	0,23	medium_impact	-0,88	0,73	0,9	11,31	24,94	N	0,31	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12714	12714	T	A	MI.20050	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	378	126	I	M	atT/atA	3,63	0,36	0,01	benign	0,05	neutral	0,14	neutral	3,73	neutral	-0,95	deleterious	-2,67	neutral_impact	0,74	neutral	0,83	neutral	0,78	deleterious	3,2	22,7	0,58	0,65	disease	0,66	disease	0,56	neutral	0,32	neutral	0,49	0	neutral	0,85	deleterious	0,55	neutral	-6	deleterious	0,59	medium_impact	0,47	medium_impact	-0,2	medium_impact	-0,53	0,74	0,85	20,07	17,52	N	0,35	N	0,64	polymorphism	1	0,1	rs386829163	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12715	12715	A	G	MI.20051	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	379	127	T	A	Acc/Gcc	-6,47	0	0	benign	0,1	neutral	0,46	neutral	3,93	neutral	1,4	deleterious	-4,72	neutral_impact	-1,06	neutral	0,69	neutral	0,64	neutral	1,17	11,6	0,73	0,75	neutral	0,39	neutral	0,09	neutral	0,3	neutral	0,23	5	neutral	0,47	deleterious	0,68	neutral	-6	deleterious	0,65	medium_impact	0,16	medium_impact	0,19	low_impact	-2,17	0,4	0,8	5,47	8,26	N	0,28	N	0,42	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12715	12715	A	T	MI.20052	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	379	127	T	S	Acc/Tcc	-6,47	0	0	possibly_damaging	0,69	neutral	0,44	neutral	4,03	neutral	1,58	deleterious	-3,78	neutral_impact	-0,36	neutral	0,71	neutral	0,67	deleterious	3,09	22,5	0,54	0,6	neutral	0,39	disease	0,54	neutral	0,39	neutral	0,47	1	neutral	0,69	neutral	0,38	neutral	-3	deleterious	0,7	low_impact	-1,08	medium_impact	0,18	low_impact	-1,53	0,62	0,8	5,47	8,26	N	0,31	N	0,57	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12715	12715	A	C	MI.20053	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	379	127	T	P	Acc/Ccc	-6,47	0	0	probably_damaging	0,96	neutral	0,15	neutral	3,7	deleterious	-3,56	deleterious	-5,72	medium_impact	3,08	neutral	0,62	neutral	0,32	deleterious	3,33	22,9	0,19	0,45	disease	0,89	disease	0,92	disease	0,73	disease	0,84	7	neutral	0,98	neutral	0,1	deleterious	1	deleterious	0,88	low_impact	-2,06	medium_impact	-0,18	medium_impact	1,61	0,54	0,8	5,47	8,26	N	0,25	N	0,94	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12716	12716	C	G	MI.20054	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	380	127	T	S	aCc/aGc	2,25	0,97	0	possibly_damaging	0,69	neutral	0,44	neutral	4,03	neutral	1,58	deleterious	-3,78	neutral_impact	-0,36	neutral	0,71	neutral	0,67	deleterious	3,29	22,8	0,54	0,6	neutral	0,39	disease	0,54	neutral	0,39	neutral	0,47	1	neutral	0,69	neutral	0,38	neutral	-3	deleterious	0,7	low_impact	-1,08	medium_impact	0,18	low_impact	-1,53	0,62	0,8	5,47	8,26	N	0,35	N	0,57	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12716	12716	C	A	MI.20055	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	380	127	T	N	aCc/aAc	2,25	0,97	0	probably_damaging	0,94	neutral	0,23	neutral	3,7	neutral	-2,26	deleterious	-4,78	low_impact	1,7	neutral	0,65	neutral	0,46	deleterious	3,47	23	0,52	0,6	disease	0,83	disease	0,8	disease	0,63	disease	0,69	4	neutral	0,96	neutral	0,15	neutral	-2	deleterious	0,81	low_impact	-1,88	medium_impact	-0,06	medium_impact	0,35	0,75	0,85	5,47	8,26	N	0,36	N	0,85	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12716	12716	C	T	MI.20056	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	380	127	T	I	aCc/aTc	2,25	0,97	0	possibly_damaging	0,9	neutral	0,49	neutral	3,73	neutral	-1,29	deleterious	-5,62	medium_impact	3,08	neutral	0,68	neutral	0,55	deleterious	3,83	23,4	0,52	0,6	neutral	0,5	disease	0,83	disease	0,61	disease	0,75	5	neutral	0,89	neutral	0,3	NA	0	deleterious	0,75	low_impact	-1,65	medium_impact	0,22	medium_impact	1,61	0,57	0,8	5,47	8,26	N	0,42	N	0,76	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12718	12718	A	T	MI.20057	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	382	128	M	L	Ata/Tta	-20	0	0	probably_damaging	0,94	neutral	1	neutral	3,15	neutral	-2,75	deleterious	-2,96	high_impact	4,65	damaging	0,43	damaging	0,04	deleterious	3,2	22,7	0,36	0,5	disease	0,69	disease	0,88	disease	0,69	disease	0,73	5	neutral	0,94	deleterious	0,53	deleterious	2	deleterious	0,63	low_impact	-1,88	high_impact	1,89	high_impact	3,04	0,35	0,8	27,36	7,25	N	0,45	N	0,97	polymorphism	0,99	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12718	12718	A	G	MI.20058	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	382	128	M	V	Ata/Gta	-20	0	0	probably_damaging	0,97	neutral	0,62	neutral	3,11	neutral	-2,97	deleterious	-3,95	high_impact	4,65	damaging	0,4	damaging	0,05	deleterious	2,51	19,53	0,46	0,55	disease	0,61	disease	0,84	disease	0,76	disease	0,78	6	neutral	0,97	neutral	0,33	deleterious	2	deleterious	0,68	low_impact	-2,18	medium_impact	0,35	high_impact	3,04	0,33	0,8	27,36	7,25	N	0,43	N	0,94	polymorphism	0,99	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12718	12718	A	C	MI.20059	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	382	128	M	L	Ata/Cta	-20	0	0	probably_damaging	0,94	neutral	1	neutral	3,15	neutral	-2,75	deleterious	-2,96	high_impact	4,65	damaging	0,43	damaging	0,04	deleterious	3,02	22,3	0,36	0,5	disease	0,69	disease	0,88	disease	0,69	disease	0,73	5	neutral	0,94	deleterious	0,53	deleterious	2	deleterious	0,63	low_impact	-1,88	high_impact	1,89	high_impact	3,04	0,35	0,8	27,36	7,25	N	0,44	N	0,97	polymorphism	0,99	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5964	5964	T	A	MI.2006	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	61	21	L	M	Tta/Ata	-3,81	0	0,03	benign	0,09	neutral	0,23	neutral	2,56	neutral	-1,79	neutral	-0,36	neutral_impact	0,49	neutral	0,75	neutral	0,89	deleterious	2,2	17,48	0,22	0,55	neutral	0,34	neutral	0,44	neutral	0,27	neutral	0,47	1	neutral	0,74	deleterious	0,57	neutral	-6	neutral	0,21	medium_impact	0,19	medium_impact	-0,1	medium_impact	-0,65	0,63	0,9	11,31	24,94	N	0,48	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12719	12719	T	A	MI.20060	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	383	128	M	K	aTa/aAa	5,46	1	0	probably_damaging	0,98	neutral	0,2	neutral	3	deleterious	-6,47	deleterious	-5,92	high_impact	5	damaging	0,46	damaging	0,04	deleterious	3,79	23,4	0,21	0,45	disease	0,94	disease	0,93	disease	0,81	disease	0,86	7	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-2,35	medium_impact	-0,1	high_impact	3,36	0,26	0,8	27,36	7,25	P	0,66	P	1	disease_causing	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12719	12719	T	C	MI.20061	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	383	128	M	T	aTa/aCa	5,46	1	0	probably_damaging	0,98	neutral	0,36	neutral	3,05	deleterious	-4,44	deleterious	-5,92	high_impact	4,11	damaging	0,43	damaging	0,06	deleterious	2,8	21,4	0,48	0,55	disease	0,83	disease	0,86	disease	0,75	disease	0,79	6	deleterious	0,98	neutral	0,19	deleterious	2	deleterious	0,84	low_impact	-2,35	medium_impact	0,1	high_impact	2,55	0,26	0,8	27,36	7,25	P	0,56	P	0,99	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12720	12720	A	T	MI.20062	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	384	128	M	I	atA/atT	5,69	1	0,01	probably_damaging	0,97	neutral	0,66	neutral	3,09	deleterious	-3,6	deleterious	-3,95	high_impact	4,11	damaging	0,44	damaging	0,05	deleterious	3,23	22,8	0,42	0,5	disease	0,74	disease	0,86	disease	0,75	disease	0,77	5	neutral	0,97	neutral	0,35	deleterious	2	deleterious	0,78	low_impact	-2,18	medium_impact	0,39	high_impact	2,55	0,43	0,8	27,36	7,25	P	0,67	P	0,96	disease_causing	1	0,27	rs2853500	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12720	12720	A	C	MI.20063	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	384	128	M	I	atA/atC	5,69	1	0,01	probably_damaging	0,97	neutral	0,66	neutral	3,09	deleterious	-3,6	deleterious	-3,95	high_impact	4,11	damaging	0,44	damaging	0,05	deleterious	3,17	22,7	0,42	0,5	disease	0,74	disease	0,86	disease	0,75	disease	0,77	5	neutral	0,97	neutral	0,35	deleterious	2	deleterious	0,78	low_impact	-2,18	medium_impact	0,39	high_impact	2,55	0,43	0,8	27,36	7,25	P	0,66	P	0,96	disease_causing	1	0,27	rs2853500	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12721	12721	C	G	MI.20064	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	385	129	L	V	Cta/Gta	0,64	0,05	0	benign	0,35	neutral	0,86	neutral	3,34	neutral	-2,43	neutral	-1,12	medium_impact	2,68	neutral	0,74	neutral	0,84	deleterious	0,31	5,81	0,56	0,6	disease	0,68	neutral	0,47	neutral	0,31	disease	0,62	2	neutral	0,24	deleterious	0,76	neutral	-3	neutral	0,35	medium_impact	-0,49	medium_impact	0,67	medium_impact	1,25	0,73	0,85	20,73	14,68	N	0,32	N	0,43	polymorphism	0,97	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12721	12721	C	A	MI.20065	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	385	129	L	M	Cta/Ata	0,64	0,05	0	probably_damaging	0,92	neutral	0,59	neutral	3,35	neutral	-2,18	neutral	0,74	low_impact	0,94	neutral	0,8	neutral	0,96	neutral	1,76	14,75	0,41	0,5	disease	0,54	neutral	0,16	neutral	0,21	neutral	0,32	4	neutral	0,9	neutral	0,34	neutral	-2	deleterious	0,62	low_impact	-1,75	medium_impact	0,32	medium_impact	-0,34	0,64	0,8	20,73	14,68	N	0,33	N	0,01	polymorphism	0,98	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12722	12722	T	G	MI.20066	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	386	129	L	R	cTa/cGa	-1,42	0	0	probably_damaging	0,97	neutral	0,3	neutral	3,22	deleterious	-5,92	deleterious	-4,15	high_impact	4,42	neutral	0,62	neutral	0,47	deleterious	3,96	23,6	0,16	0,45	disease	0,94	disease	0,91	disease	0,72	disease	0,84	7	neutral	0,97	neutral	0,17	deleterious	2	deleterious	0,88	low_impact	-2,18	medium_impact	0,03	high_impact	2,83	0,57	0,8	20,73	14,68	N	0,49	N	0,83	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12722	12722	T	C	MI.20067	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	386	129	L	P	cTa/cCa	-1,42	0	0	probably_damaging	0,97	neutral	0,14	neutral	3,23	deleterious	-6,24	deleterious	-4,92	medium_impact	3,32	neutral	0,68	neutral	0,39	deleterious	3,75	23,3	0,19	0,45	disease	0,95	disease	0,89	disease	0,72	disease	0,85	7	deleterious	0,98	neutral	0,09	deleterious	1	deleterious	0,88	low_impact	-2,18	medium_impact	-0,2	medium_impact	1,83	0,7	0,85	20,73	14,68	N	0,29	N	0,91	disease_causing	0,63	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12722	12722	T	A	MI.20068	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	386	129	L	Q	cTa/cAa	-1,42	0	0	probably_damaging	0,97	neutral	0,34	neutral	3,23	deleterious	-4,77	deleterious	-3,65	high_impact	4,07	neutral	0,68	neutral	0,56	deleterious	3,98	23,6	0,2	0,45	disease	0,94	disease	0,73	disease	0,6	disease	0,83	7	neutral	0,97	neutral	0,19	deleterious	2	deleterious	0,81	low_impact	-2,18	medium_impact	0,07	high_impact	2,52	0,75	0,85	20,73	14,68	N	0,4	N	0,83	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12724	12724	A	C	MI.20069	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	388	130	I	L	Atc/Ctc	-1,42	0	0	benign	0,4	neutral	0,92	neutral	3,85	neutral	0,96	neutral	-1,89	low_impact	0,94	neutral	0,74	damaging	0,26	deleterious	3,55	23,1	0,33	0,5	neutral	0,42	disease	0,67	neutral	0,31	neutral	0,48	0	neutral	0,32	deleterious	0,76	neutral	-6	deleterious	0,61	medium_impact	-0,58	medium_impact	0,82	medium_impact	-0,34	0,38	0,8	2,99	7,61	N	0,22	N	0,63	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5965	5965	T	C	MI.2007	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	62	21	L	S	tTa/tCa	-1,96	0	0	possibly_damaging	0,76	deleterious	0	neutral	2,58	neutral	-1,82	neutral	-1,86	medium_impact	2,55	damaging	0,56	damaging	0,15	deleterious	3,66	23,2	0,22	0,55	neutral	0,45	disease	0,72	disease	0,51	disease	0,59	2	deleterious	1	neutral	0,12	deleterious	4	deleterious	0,72	low_impact	-1,23	low_impact	-1,48	medium_impact	1,26	0,73	0,9	11,31	24,94	N	0,33	N	0,73	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12724	12724	A	T	MI.20070	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	388	130	I	F	Atc/Ttc	-1,42	0	0	probably_damaging	0,94	neutral	0,71	neutral	3,67	neutral	-1,32	deleterious	-3,79	medium_impact	2,02	neutral	0,8	damaging	0,12	deleterious	3,65	23,2	0,37	0,5	disease	0,61	disease	0,81	neutral	0,48	disease	0,62	2	neutral	0,93	neutral	0,39	deleterious	1	deleterious	0,76	low_impact	-1,88	medium_impact	0,45	medium_impact	0,64	0,51	0,8	2,99	7,61	N	0,16	N	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12724	12724	A	G	MI.20071	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	388	130	I	V	Atc/Gtc	-1,42	0	0	benign	0,4	neutral	0,53	neutral	3,73	neutral	0,11	neutral	-0,84	low_impact	1,9	neutral	0,79	neutral	0,95	neutral	1,72	14,5	0,56	0,6	disease	0,51	neutral	0,28	neutral	0,33	neutral	0,35	3	neutral	0,42	deleterious	0,57	neutral	-6	deleterious	0,59	medium_impact	-0,58	medium_impact	0,26	medium_impact	0,53	0,34	0,8	2,99	7,61	N	0,33	N	0,08	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12725	12725	T	G	MI.20072	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	389	130	I	S	aTc/aGc	3,17	0,07	0	possibly_damaging	0,65	neutral	0,57	neutral	3,62	neutral	-1,84	deleterious	-5,58	medium_impact	3,17	neutral	0,7	damaging	0,1	deleterious	4,11	23,8	0,34	0,5	disease	0,51	disease	0,84	disease	0,56	disease	0,69	4	neutral	0,6	neutral	0,46	NA	0	deleterious	0,74	low_impact	-1	medium_impact	0,3	medium_impact	1,69	0,42	0,8	2,99	7,61	N	0,26	N	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12725	12725	T	C	MI.20073	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	389	130	I	T	aTc/aCc	3,17	0,07	0	benign	0,08	neutral	0,47	neutral	3,64	neutral	-1,31	deleterious	-4,46	low_impact	0,99	neutral	0,78	neutral	0,35	deleterious	2,22	17,64	0,49	0,55	disease	0,7	neutral	0,41	neutral	0,35	disease	0,63	3	neutral	0,47	deleterious	0,7	neutral	-6	deleterious	0,73	medium_impact	0,26	medium_impact	0,2	medium_impact	-0,3	0,5	0,8	2,99	7,61	N	0,32	N	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12725	12725	T	A	MI.20074	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	389	130	I	N	aTc/aAc	3,17	0,07	0	possibly_damaging	0,89	neutral	0,44	neutral	3,59	neutral	-2,87	deleterious	-6,57	medium_impact	3,09	neutral	0,69	damaging	0,11	deleterious	4,51	24,3	0,29	0,45	disease	0,82	disease	0,84	disease	0,58	disease	0,72	4	neutral	0,88	neutral	0,28	NA	0	deleterious	0,81	low_impact	-1,61	medium_impact	0,18	medium_impact	1,62	0,51	0,8	2,99	7,61	N	0,33	N	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12726	12726	C	A	MI.20075	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	390	130	I	M	atC/atA	0,64	0,04	0	probably_damaging	0,94	neutral	0,47	neutral	3,69	neutral	-0,48	deleterious	-2,8	medium_impact	1,99	neutral	0,72	damaging	0,23	deleterious	3,68	23,3	0,39	0,5	disease	0,68	disease	0,53	neutral	0,44	disease	0,51	0	neutral	0,94	neutral	0,27	deleterious	1	deleterious	0,72	low_impact	-1,88	medium_impact	0,2	medium_impact	0,62	0,56	0,8	2,99	7,61	N	0,28	N	0,58	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12726	12726	C	G	MI.20076	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	390	130	I	M	atC/atG	0,64	0,04	0	probably_damaging	0,94	neutral	0,47	neutral	3,69	neutral	-0,48	deleterious	-2,8	medium_impact	1,99	neutral	0,72	damaging	0,23	deleterious	3,27	22,8	0,39	0,5	disease	0,68	disease	0,53	neutral	0,44	disease	0,51	0	neutral	0,94	neutral	0,27	deleterious	1	deleterious	0,72	low_impact	-1,88	medium_impact	0,2	medium_impact	0,62	0,56	0,8	2,99	7,61	N	0,28	N	0,58	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12727	12727	T	G	MI.20077	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	391	131	L	V	Tta/Gta	-8,3	0	0	probably_damaging	1	neutral	0,7	neutral	3,49	neutral	-0,54	deleterious	-2,96	medium_impact	3,04	damaging	0,41	damaging	0,04	deleterious	3,3	22,9	0,48	0,55	disease	0,67	disease	0,65	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,44	medium_impact	1,57	0,68	0,85	30,35	7,18	N	0,38	N	0,78	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12727	12727	T	A	MI.20078	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	391	131	L	M	Tta/Ata	-8,3	0	0	probably_damaging	1	neutral	0,32	neutral	3,32	neutral	-2,21	neutral	-1,97	medium_impact	3,41	damaging	0,39	damaging	0,11	deleterious	3,46	23	0,4	0,5	disease	0,77	disease	0,65	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,05	medium_impact	1,91	0,74	0,85	30,35	7,18	N	0,45	N	0,85	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12728	12728	T	G	MI.20079	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	392	131	L	W	tTa/tGa	-1,88	0	0	probably_damaging	1	neutral	0,15	neutral	3,2	deleterious	-6,88	deleterious	-5,92	high_impact	4,88	damaging	0,44	damaging	0,02	deleterious	3,63	23,2	0,13	0,4	disease	0,98	disease	0,8	disease	0,69	disease	0,83	7	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,18	high_impact	3,26	0,53	0,8	30,35	7,18	P	0,5	N	0,98	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5965	5965	T	G	MI.2008	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	62	21	L	W	tTa/tGa	-1,96	0	0	probably_damaging	0,96	deleterious	0	neutral	2,53	deleterious	-4,62	neutral	-2,16	medium_impact	2,55	damaging	0,59	damaging	0,11	deleterious	3,56	23,1	0,1	0,55	disease	0,55	disease	0,85	disease	0,52	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-2,06	low_impact	-1,48	medium_impact	1,26	0,52	0,9	11,31	24,94	N	0,24	N	0,92	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12728	12728	T	C	MI.20080	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	392	131	L	S	tTa/tCa	-1,88	0	0	probably_damaging	1	neutral	0,91	neutral	3,24	deleterious	-3,65	deleterious	-5,92	high_impact	4,08	damaging	0,44	damaging	0,04	deleterious	3,63	23,2	0,23	0,45	disease	0,81	disease	0,78	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,46	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,79	high_impact	2,52	0,74	0,85	30,35	7,18	N	0,31	N	0,98	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12729	12729	A	C	MI.20081	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	393	131	L	F	ttA/ttC	5,69	0,87	0	probably_damaging	1	neutral	0,67	neutral	3,26	deleterious	-3,1	deleterious	-3,95	medium_impact	3,25	damaging	0,4	damaging	0,05	deleterious	3,33	22,9	0,47	0,55	disease	0,87	disease	0,74	disease	0,58	disease	0,7	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,4	medium_impact	1,77	0,77	0,85	30,35	7,18	P	0,57	P	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12729	12729	A	T	MI.20082	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	393	131	L	F	ttA/ttT	5,69	0,87	0	probably_damaging	1	neutral	0,67	neutral	3,26	deleterious	-3,1	deleterious	-3,95	medium_impact	3,25	damaging	0,4	damaging	0,05	deleterious	3,46	23	0,47	0,55	disease	0,87	disease	0,74	disease	0,58	disease	0,7	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,4	medium_impact	1,77	0,77	0,85	30,35	7,18	P	0,58	P	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12730	12730	G	T	MI.20083	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	394	132	V	F	Gtt/Ttt	-2,57	0	0	possibly_damaging	0,64	neutral	0,69	neutral	3,41	neutral	-1,52	deleterious	-4,65	high_impact	4,53	neutral	0,63	neutral	0,43	deleterious	3,37	22,9	0,3	0,45	disease	0,57	disease	0,94	disease	0,65	disease	0,78	6	neutral	0,57	deleterious	0,53	deleterious	1	deleterious	0,68	medium_impact	-0,98	medium_impact	0,42	high_impact	2,94	0,71	0,85	14,1	14,48	N	0,39	N	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12730	12730	G	A	MI.20084	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	394	132	V	I	Gtt/Att	-2,57	0	0	benign	0,01	neutral	0,41	neutral	3,37	neutral	-2,58	neutral	-0,88	low_impact	1,27	neutral	0,76	neutral	0,66	deleterious	0,39	6,53	0,56	0,6	disease	0,68	disease	0,54	neutral	0,4	neutral	0,48	0	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,2	medium_impact	1,15	medium_impact	0,15	medium_impact	-0,04	0,95	0,95	14,1	14,48	N	0,27	N	0,38	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12730	12730	G	C	MI.20085	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	394	132	V	L	Gtt/Ctt	-2,57	0	0	benign	0,14	neutral	0,66	neutral	3,31	neutral	-2,49	deleterious	-2,73	medium_impact	2,46	neutral	0,68	neutral	0,51	neutral	1,52	13,41	0,46	0,55	disease	0,71	disease	0,85	disease	0,55	disease	0,64	3	neutral	0,22	deleterious	0,76	neutral	-3	neutral	0,31	medium_impact	0	medium_impact	0,39	medium_impact	1,04	0,7	0,85	14,1	14,48	N	0,23	N	0,54	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12731	12731	T	G	MI.20086	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	395	132	V	G	gTt/gGt	2,02	0,91	0	possibly_damaging	0,6	neutral	0,34	neutral	3,21	deleterious	-5,62	deleterious	-6,61	high_impact	4,53	neutral	0,66	neutral	0,6	deleterious	3,48	23,1	0,22	0,45	disease	0,56	disease	0,88	disease	0,67	disease	0,74	5	neutral	0,69	neutral	0,37	deleterious	1	deleterious	0,68	medium_impact	-0,91	medium_impact	0,07	high_impact	2,94	0,6	0,8	14,1	14,48	N	0,47	N	0,89	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12731	12731	T	C	MI.20087	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	395	132	V	A	gTt/gCt	2,02	0,91	0	benign	0,22	neutral	0,56	neutral	3,32	neutral	-2,32	deleterious	-3,71	medium_impact	2,87	neutral	0,69	neutral	0,63	neutral	1,75	14,67	0,47	0,55	disease	0,68	disease	0,69	disease	0,63	disease	0,61	2	neutral	0,33	deleterious	0,67	neutral	-3	deleterious	0,49	medium_impact	-0,22	medium_impact	0,29	medium_impact	1,42	0,55	0,8	14,1	14,48	N	0,29	N	0,67	polymorphism	1	0,19	.	.	.	.	.	.	COSM218996	.	.	.	.	.	.	.	.
chrM	12731	12731	T	A	MI.20088	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	395	132	V	D	gTt/gAt	2,02	0,91	0	possibly_damaging	0,77	neutral	0,24	neutral	3,19	deleterious	-7,25	deleterious	-6,5	high_impact	4,53	neutral	0,63	neutral	0,42	deleterious	4,33	24	0,11	0,4	disease	0,96	disease	0,92	disease	0,76	disease	0,86	7	neutral	0,85	neutral	0,24	deleterious	1	deleterious	0,81	low_impact	-1,24	medium_impact	-0,04	high_impact	2,94	0,68	0,85	14,1	14,48	N	0,5	N	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12733	12733	A	C	MI.20089	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	397	133	T	P	Acc/Ccc	-11,51	0	0	probably_damaging	0,96	neutral	0,2	neutral	3,53	deleterious	-4,37	deleterious	-5,28	high_impact	3,66	neutral	0,64	damaging	0,13	deleterious	3,35	22,9	0,22	0,45	disease	0,87	disease	0,9	disease	0,77	disease	0,86	7	neutral	0,97	neutral	0,12	deleterious	2	deleterious	0,84	low_impact	-2,06	medium_impact	-0,1	high_impact	2,14	0,64	0,8	14,76	14,74	N	0,35	N	0,98	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5966	5966	A	T	MI.2009	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	63	21	L	F	ttA/ttT	7,53	0,98	0	benign	0,42	neutral	0,07	neutral	2,57	neutral	-2,02	neutral	-1,07	low_impact	1,66	neutral	0,6	damaging	0,12	deleterious	3,36	22,9	0,29	0,55	neutral	0,37	disease	0,74	neutral	0,41	disease	0,56	1	neutral	0,92	neutral	0,33	neutral	-6	deleterious	0,62	medium_impact	-0,62	medium_impact	-0,43	medium_impact	0,43	0,66	0,9	11,31	24,94	N	0,5	N	0,87	polymorphism	0,55	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12733	12733	A	G	MI.20090	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	397	133	T	A	Acc/Gcc	-11,51	0	0	possibly_damaging	0,58	neutral	0,5	neutral	3,62	neutral	-0,42	deleterious	-4,13	medium_impact	2,38	neutral	0,71	damaging	0,26	deleterious	3,37	22,9	0,74	0,8	disease	0,52	disease	0,65	disease	0,63	disease	0,61	2	neutral	0,56	neutral	0,46	NA	0	deleterious	0,73	medium_impact	-0,88	medium_impact	0,23	medium_impact	0,97	0,56	0,8	14,76	14,74	N	0,25	N	0,71	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12733	12733	A	T	MI.20091	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	397	133	T	S	Acc/Tcc	-11,51	0	0	benign	0,25	neutral	0,41	neutral	3,7	neutral	-0,11	deleterious	-2,82	neutral_impact	0,58	neutral	0,76	neutral	0,89	neutral	1,72	14,52	0,67	0,7	disease	0,51	neutral	0,43	neutral	0,39	neutral	0,32	4	neutral	0,5	deleterious	0,58	neutral	-6	deleterious	0,71	medium_impact	-0,29	medium_impact	0,15	medium_impact	-0,67	0,81	0,85	14,76	14,74	N	0,34	N	0,17	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12734	12734	C	A	MI.20092	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	398	133	T	N	aCc/aAc	1,33	0,05	0	possibly_damaging	0,84	neutral	0,32	neutral	3,53	deleterious	-4,2	deleterious	-4,13	medium_impact	3,31	neutral	0,72	damaging	0,11	deleterious	3,49	23,1	0,53	0,6	disease	0,9	disease	0,84	disease	0,66	disease	0,78	6	neutral	0,86	neutral	0,24	NA	0	deleterious	0,8	low_impact	-1,43	medium_impact	0,05	medium_impact	1,82	0,78	0,85	14,76	14,74	N	0,3	N	0,63	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12734	12734	C	G	MI.20093	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	398	133	T	S	aCc/aGc	1,33	0,05	0	benign	0,25	neutral	0,41	neutral	3,7	neutral	-0,11	deleterious	-2,82	neutral_impact	0,58	neutral	0,76	neutral	0,89	deleterious	1,92	15,69	0,67	0,7	disease	0,51	neutral	0,43	neutral	0,39	neutral	0,32	4	neutral	0,5	deleterious	0,58	neutral	-6	deleterious	0,71	medium_impact	-0,29	medium_impact	0,15	medium_impact	-0,67	0,81	0,85	14,76	14,74	N	0,35	N	0,17	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12734	12734	C	T	MI.20094	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	398	133	T	I	aCc/aTc	1,33	0,05	0	probably_damaging	0,96	neutral	0,4	neutral	3,64	neutral	-0,73	deleterious	-5,44	low_impact	1,5	neutral	0,76	damaging	0,28	deleterious	3,84	23,4	0,61	0,65	disease	0,57	disease	0,83	disease	0,58	disease	0,56	1	neutral	0,96	neutral	0,22	neutral	-2	deleterious	0,76	low_impact	-2,06	medium_impact	0,14	medium_impact	0,17	0,65	0,8	14,76	14,74	N	0,25	N	0,91	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12736	12736	G	A	MI.20095	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	400	134	A	T	Gct/Act	-11,28	0	0	probably_damaging	0,94	neutral	0,67	neutral	4,26	deleterious	-3,42	deleterious	-3,66	medium_impact	2,32	neutral	0,67	neutral	0,52	deleterious	4,09	23,7	0,61	0,65	disease	0,73	disease	0,82	disease	0,67	disease	0,59	2	neutral	0,93	neutral	0,37	deleterious	1	deleterious	0,83	low_impact	-1,88	medium_impact	0,4	medium_impact	0,92	0,75	0,85	8,13	7,47	N	0,23	N	0,94	polymorphism	1	0,12	.	.	.	.	.	.	COSM488733	.	.	.	.	.	.	.	.
chrM	12736	12736	G	T	MI.20096	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	400	134	A	S	Gct/Tct	-11,28	0	0	possibly_damaging	0,57	neutral	0,65	neutral	5,06	neutral	1,2	deleterious	-2,53	neutral_impact	0,28	neutral	0,66	neutral	0,65	deleterious	3,53	23,1	0,55	0,6	neutral	0,48	disease	0,67	neutral	0,49	neutral	0,46	1	neutral	0,5	deleterious	0,54	neutral	-3	deleterious	0,77	medium_impact	-0,86	medium_impact	0,38	medium_impact	-0,95	0,91	0,95	8,13	7,47	N	0,29	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12736	12736	G	C	MI.20097	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	400	134	A	P	Gct/Cct	-11,28	0	0	probably_damaging	0,99	neutral	0,24	neutral	4,26	deleterious	-3,46	deleterious	-4,72	high_impact	4,46	neutral	0,67	neutral	0,33	deleterious	3,74	23,3	0,24	0,45	disease	0,96	disease	0,93	disease	0,79	disease	0,85	7	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,9	low_impact	-2,64	medium_impact	-0,04	high_impact	2,87	0,73	0,85	8,13	7,47	N	0,54	P	0,96	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12737	12737	C	A	MI.20098	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	401	134	A	D	gCt/gAt	5,92	1	0	probably_damaging	0,98	neutral	0,33	neutral	4,23	deleterious	-5,35	deleterious	-5,56	high_impact	4,46	neutral	0,68	neutral	0,38	deleterious	4,32	24	0,19	0,45	disease	0,97	disease	0,93	disease	0,77	disease	0,84	7	deleterious	0,98	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-2,35	medium_impact	0,06	high_impact	2,87	0,7	0,85	8,13	7,47	P	0,63	P	0,95	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12737	12737	C	T	MI.20099	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	401	134	A	V	gCt/gTt	5,92	1	0	probably_damaging	0,97	neutral	0,55	neutral	4,3	neutral	-2,53	deleterious	-3,87	medium_impact	3,02	neutral	0,66	neutral	0,36	deleterious	4,27	24	0,49	0,55	disease	0,75	disease	0,88	disease	0,62	disease	0,7	4	neutral	0,96	neutral	0,29	deleterious	1	deleterious	0,84	low_impact	-2,18	medium_impact	0,28	medium_impact	1,56	0,71	0,85	8,13	7,47	P	0,5	N	0,76	disease_causing	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8620	8620	C	G	MI.201	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	94	32	P	A	Ccc/Gcc	-6,35	0	0	probably_damaging	1	neutral	0,08	neutral	4,5	neutral	2,37	deleterious	-6,2	medium_impact	2,42	neutral	0,86	damaging	0,19	deleterious	2,93	22	0,45	0,65	disease	0,58	disease	0,56	neutral	0,5	neutral	0,46	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	-0,31	medium_impact	0,98	0,65	0,9	29,2	19,38	N	0,32	N	0,73	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5966	5966	A	C	MI.2010	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	63	21	L	F	ttA/ttC	7,53	0,98	0	benign	0,42	neutral	0,07	neutral	2,57	neutral	-2,02	neutral	-1,07	low_impact	1,66	neutral	0,6	damaging	0,12	deleterious	3,32	22,9	0,29	0,55	neutral	0,37	disease	0,74	neutral	0,41	disease	0,56	1	neutral	0,92	neutral	0,33	neutral	-6	deleterious	0,62	medium_impact	-0,62	medium_impact	-0,43	medium_impact	0,43	0,66	0,9	11,31	24,94	N	0,5	N	0,87	polymorphism	0,55	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12737	12737	C	G	MI.20100	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	401	134	A	G	gCt/gGt	5,92	1	0	possibly_damaging	0,9	neutral	0,39	neutral	4,25	deleterious	-3,84	deleterious	-3,73	medium_impact	2,4	neutral	0,66	neutral	0,5	deleterious	3,85	23,4	0,38	0,5	disease	0,88	disease	0,82	disease	0,68	disease	0,75	5	neutral	0,9	neutral	0,25	NA	0	deleterious	0,81	low_impact	-1,65	medium_impact	0,13	medium_impact	0,99	0,86	0,9	8,13	7,47	P	0,57	P	0,82	disease_causing	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12739	12739	A	C	MI.20101	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	403	135	N	H	Aac/Cac	-7,38	0	0	probably_damaging	1	neutral	0,54	neutral	4,49	deleterious	-3,41	deleterious	-4,93	medium_impact	3,29	neutral	0,64	damaging	0,12	deleterious	2,93	22	0,64	0,7	disease	0,78	disease	0,9	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,27	medium_impact	1,8	0,49	0,8	18,57	7,13	N	0,23	N	0,97	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12739	12739	A	T	MI.20102	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	403	135	N	Y	Aac/Tac	-7,38	0	0	probably_damaging	1	neutral	1	neutral	4,52	deleterious	-3,66	deleterious	-7,89	medium_impact	3,29	neutral	0,69	damaging	0,09	deleterious	3,63	23,2	0,47	0,55	disease	0,84	disease	0,94	disease	0,7	disease	0,81	6	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,86	low_impact	-3,6	high_impact	1,89	medium_impact	1,8	0,4	0,8	18,57	7,13	N	0,24	N	0,99	polymorphism	0,95	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12739	12739	A	G	MI.20103	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	403	135	N	D	Aac/Gac	-7,38	0	0	probably_damaging	1	neutral	0,21	neutral	4,57	neutral	0,34	deleterious	-4,93	low_impact	0,82	neutral	0,66	damaging	0,18	deleterious	3,73	23,3	0,76	0,8	neutral	0,46	disease	0,72	disease	0,64	disease	0,54	1	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	-0,09	medium_impact	-0,45	0,57	0,8	18,57	7,13	N	0,27	N	0,94	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12740	12740	A	C	MI.20104	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	404	135	N	T	aAc/aCc	8,44	1	0	probably_damaging	1	neutral	0,4	neutral	4,52	neutral	-1,19	deleterious	-5,92	medium_impact	2,9	neutral	0,69	damaging	0,09	deleterious	3,27	22,8	0,64	0,7	disease	0,69	disease	0,88	disease	0,66	disease	0,73	5	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,14	medium_impact	1,45	0,49	0,8	18,57	7,13	N	0,45	N	0,94	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12740	12740	A	G	MI.20105	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	404	135	N	S	aAc/aGc	8,44	1	0	probably_damaging	1	neutral	0,41	neutral	4,64	neutral	-1,17	deleterious	-4,93	low_impact	1,85	neutral	0,7	damaging	0,16	deleterious	2,97	22,1	0,76	0,8	disease	0,57	disease	0,85	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	0,15	medium_impact	0,49	0,26	0,8	18,57	7,13	N	0,44	N	0,82	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12740	12740	A	T	MI.20106	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	404	135	N	I	aAc/aTc	8,44	1	0	probably_damaging	1	neutral	0,4	neutral	4,47	deleterious	-3,35	deleterious	-8,88	medium_impact	2,94	neutral	0,66	damaging	0,1	deleterious	3,76	23,3	0,43	0,55	disease	0,59	disease	0,96	disease	0,66	disease	0,8	6	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,14	medium_impact	1,48	0,23	0,8	18,57	7,13	N	0,42	N	0,99	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12741	12741	C	A	MI.20107	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	405	135	N	K	aaC/aaA	8,44	1	0	probably_damaging	1	neutral	0,31	neutral	4,55	neutral	-1,69	deleterious	-5,92	medium_impact	3,4	neutral	0,7	damaging	0,09	deleterious	4,3	24	0,68	0,7	disease	0,66	disease	0,94	disease	0,69	disease	0,79	6	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,04	medium_impact	1,9	0,56	0,8	18,57	7,13	N	0,49	N	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12741	12741	C	G	MI.20108	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	405	135	N	K	aaC/aaG	8,44	1	0	probably_damaging	1	neutral	0,31	neutral	4,55	neutral	-1,69	deleterious	-5,92	medium_impact	3,4	neutral	0,7	damaging	0,09	deleterious	3,81	23,4	0,68	0,7	disease	0,66	disease	0,94	disease	0,69	disease	0,79	6	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,04	medium_impact	1,9	0,56	0,8	18,57	7,13	N	0,49	N	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12742	12742	A	C	MI.20109	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	406	136	N	H	Aac/Cac	-1,65	0	0	probably_damaging	1	neutral	0,57	neutral	4,26	deleterious	-3,88	deleterious	-4,93	medium_impact	3,21	damaging	0,57	damaging	0,03	deleterious	2,83	21,5	0,42	0,55	disease	0,85	disease	0,89	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,3	medium_impact	1,73	0,46	0,8	28,86	7,2	N	0,22	N	0,97	disease_causing	0,98	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5967	5967	T	A	MI.2011	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	64	22	F	I	Ttc/Atc	-0,34	0,55	0	probably_damaging	0,99	neutral	0,05	neutral	2,81	deleterious	-3,14	neutral	-2,07	medium_impact	2,98	neutral	0,7	damaging	0,16	deleterious	4,13	23,8	0,23	0,55	neutral	0,38	disease	0,83	disease	0,57	disease	0,68	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,79	low_impact	-2,64	medium_impact	-0,52	medium_impact	1,65	0,64	0,9	2,92	6,69	N	0,3	N	0,88	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12742	12742	A	T	MI.20110	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	406	136	N	Y	Aac/Tac	-1,65	0	0	probably_damaging	1	neutral	1	neutral	4,21	deleterious	-6,18	deleterious	-7,89	high_impact	4,01	damaging	0,57	damaging	0,03	deleterious	3,37	22,9	0,33	0,5	disease	0,94	disease	0,93	disease	0,72	disease	0,82	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,88	low_impact	-3,6	high_impact	1,89	high_impact	2,46	0,36	0,8	28,86	7,2	N	0,3	N	0,99	disease_causing	0,99	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12742	12742	A	G	MI.20111	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	406	136	N	D	Aac/Gac	-1,65	0	0	probably_damaging	1	neutral	0,44	neutral	4,59	neutral	-0,24	deleterious	-4,93	medium_impact	2,38	damaging	0,57	damaging	0,04	deleterious	3,57	23,2	0,64	0,7	neutral	0,46	disease	0,84	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,18	medium_impact	0,97	0,75	0,85	28,86	7,2	N	0,21	N	0,94	disease_causing	0,95	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12743	12743	A	C	MI.20112	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	407	136	N	T	aAc/aCc	6,84	1	0	probably_damaging	1	neutral	0,62	neutral	4,23	deleterious	-4,26	deleterious	-5,92	high_impact	3,52	damaging	0,47	damaging	0,02	deleterious	3,75	23,3	0,4	0,5	disease	0,8	disease	0,88	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,35	high_impact	2,01	0,48	0,8	28,86	7,2	N	0,48	N	0,94	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12743	12743	A	G	MI.20113	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	407	136	N	S	aAc/aGc	6,84	1	0	probably_damaging	1	neutral	0,71	neutral	4,34	neutral	-2,98	deleterious	-4,93	low_impact	1,49	damaging	0,48	damaging	0,07	deleterious	3,51	23,1	0,63	0,7	disease	0,74	disease	0,82	disease	0,63	disease	0,56	1	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,82	low_impact	-3,6	medium_impact	0,45	medium_impact	0,16	0,41	0,8	28,86	7,2	N	0,43	N	0,82	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12743	12743	A	T	MI.20114	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	407	136	N	I	aAc/aTc	6,84	1	0	probably_damaging	1	neutral	0,47	neutral	4,21	deleterious	-6,38	deleterious	-8,88	high_impact	4,91	damaging	0,55	damaging	0,03	deleterious	4,33	24	0,28	0,45	disease	0,91	disease	0,95	disease	0,68	disease	0,81	6	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,2	high_impact	3,28	0,33	0,8	28,86	7,2	P	0,6	P	0,99	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12744	12744	C	A	MI.20115	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	408	136	N	K	aaC/aaA	6,84	1	0	probably_damaging	1	neutral	0,66	neutral	4,26	deleterious	-3,99	deleterious	-5,92	high_impact	4,36	damaging	0,59	damaging	0,02	deleterious	4,39	24,1	0,44	0,55	disease	0,8	disease	0,92	disease	0,75	disease	0,82	6	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,39	high_impact	2,78	0,56	0,8	28,86	7,2	P	0,54	P	1	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12744	12744	C	G	MI.20116	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	408	136	N	K	aaC/aaG	6,84	1	0	probably_damaging	1	neutral	0,66	neutral	4,26	deleterious	-3,99	deleterious	-5,92	high_impact	4,36	damaging	0,59	damaging	0,02	deleterious	3,91	23,5	0,44	0,55	disease	0,8	disease	0,92	disease	0,75	disease	0,82	6	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,39	high_impact	2,78	0,56	0,8	28,86	7,2	P	0,54	P	1	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12745	12745	C	G	MI.20117	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	409	137	L	V	Cta/Gta	-2,57	0	0	possibly_damaging	0,9	neutral	0,59	neutral	4,15	deleterious	-3,06	neutral	-2,27	medium_impact	2,85	neutral	0,69	damaging	0,13	deleterious	3,3	22,9	0,52	0,6	disease	0,79	disease	0,72	disease	0,59	disease	0,7	4	neutral	0,88	neutral	0,35	NA	0	deleterious	0,81	low_impact	-1,65	medium_impact	0,32	medium_impact	1,4	0,8	0,85	3,98	8,46	N	0,17	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12745	12745	C	A	MI.20118	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	409	137	L	M	Cta/Ata	-2,57	0	0	possibly_damaging	0,76	neutral	0,25	neutral	4,03	deleterious	-3,51	neutral	-0,92	low_impact	1,35	neutral	0,76	neutral	0,92	neutral	1,62	13,97	0,39	0,5	disease	0,77	neutral	0,08	neutral	0,33	neutral	0,34	3	neutral	0,84	neutral	0,25	neutral	-3	deleterious	0,71	low_impact	-1,22	medium_impact	-0,03	medium_impact	0,03	0,8	0,85	3,98	8,46	N	0,45	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12746	12746	T	A	MI.20119	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	410	137	L	Q	cTa/cAa	-4,4	0	0	probably_damaging	0,99	neutral	0,31	neutral	4,01	deleterious	-6,61	deleterious	-4,9	high_impact	4,75	neutral	0,69	damaging	0,12	deleterious	4,01	23,6	0,21	0,45	disease	0,95	disease	0,87	disease	0,67	disease	0,84	7	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,87	low_impact	-2,64	medium_impact	0,04	high_impact	3,14	0,77	0,85	3,98	8,46	P	0,64	P	0,84	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5967	5967	T	C	MI.2012	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	64	22	F	L	Ttc/Ctc	-0,34	0,55	0	probably_damaging	0,98	neutral	0,21	neutral	2,91	neutral	-2,6	neutral	-1,98	low_impact	1,35	damaging	0,51	damaging	0,18	deleterious	2,54	19,7	0,32	0,55	neutral	0,19	disease	0,72	neutral	0,41	disease	0,56	1	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,72	low_impact	-2,35	medium_impact	-0,13	medium_impact	0,15	0,56	0,9	2,92	6,69	N	0,38	N	0,83	disease_causing	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12746	12746	T	C	MI.20120	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	410	137	L	P	cTa/cCa	-4,4	0	0	probably_damaging	1	neutral	0,22	neutral	4	deleterious	-6,42	deleterious	-6	high_impact	3,94	damaging	0,57	damaging	0,1	deleterious	3,82	23,4	0,25	0,45	disease	0,94	disease	0,95	disease	0,77	disease	0,87	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	-0,07	high_impact	2,4	0,83	0,85	3,98	8,46	N	0,33	N	0,99	disease_causing	0,78	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12746	12746	T	G	MI.20121	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	410	137	L	R	cTa/cGa	-4,4	0	0	probably_damaging	0,99	neutral	0,38	neutral	4,01	deleterious	-6,42	deleterious	-5,08	high_impact	4,75	neutral	0,62	damaging	0,1	deleterious	4,11	23,8	0,19	0,45	disease	0,95	disease	0,95	disease	0,77	disease	0,87	7	deleterious	0,99	neutral	0,2	deleterious	2	deleterious	0,93	low_impact	-2,64	medium_impact	0,12	high_impact	3,14	0,62	0,8	3,98	8,46	P	0,66	P	0,97	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12748	12748	T	C	MI.20122	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	412	138	F	L	Ttc/Ctc	-4,63	0	0	benign	0,08	neutral	0,68	neutral	4,89	neutral	0,51	deleterious	-4,56	neutral_impact	0,23	neutral	0,8	neutral	0,88	neutral	0,92	10,18	0,45	0,55	neutral	0,49	disease	0,79	neutral	0,45	disease	0,51	0	neutral	0,22	deleterious	0,8	neutral	-6	neutral	0,2	medium_impact	0,26	medium_impact	0,41	medium_impact	-0,99	0,78	0,85	4,15	8,74	N	0,2	N	0,44	disease_causing	0,74	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12748	12748	T	G	MI.20123	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	412	138	F	V	Ttc/Gtc	-4,63	0	0	possibly_damaging	0,74	neutral	0,5	neutral	4,58	neutral	-0,74	deleterious	-5,74	low_impact	1,34	neutral	0,69	neutral	0,65	deleterious	2,35	18,46	0,35	0,5	disease	0,56	disease	0,89	disease	0,63	disease	0,56	1	neutral	0,72	neutral	0,38	neutral	-3	deleterious	0,46	low_impact	-1,18	medium_impact	0,23	medium_impact	0,02	0,65	0,8	4,15	8,74	N	0,24	N	0,91	disease_causing	0,85	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12748	12748	T	A	MI.20124	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	412	138	F	I	Ttc/Atc	-4,63	0	0	possibly_damaging	0,63	neutral	0,42	neutral	4,82	neutral	-0,46	deleterious	-4,8	neutral_impact	0,35	neutral	0,66	neutral	0,68	deleterious	2,6	20,2	0,36	0,5	neutral	0,5	disease	0,87	disease	0,56	disease	0,53	1	neutral	0,65	neutral	0,4	neutral	-3	neutral	0,43	medium_impact	-0,97	medium_impact	0,16	medium_impact	-0,88	0,57	0,8	4,15	8,74	N	0,23	N	0,83	disease_causing	0,72	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12749	12749	T	A	MI.20125	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	413	138	F	Y	tTc/tAc	1,33	0,94	0	possibly_damaging	0,89	neutral	1	neutral	4,48	deleterious	-3,63	deleterious	-2,66	low_impact	1,9	neutral	0,61	neutral	0,64	deleterious	4,09	23,7	0,3	0,45	disease	0,86	disease	0,85	disease	0,59	disease	0,68	4	neutral	0,89	deleterious	0,56	neutral	-3	deleterious	0,7	low_impact	-1,61	high_impact	1,89	medium_impact	0,53	0,68	0,85	4,15	8,74	N	0,35	N	0,69	polymorphism	0,56	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12749	12749	T	C	MI.20126	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	413	138	F	S	tTc/tCc	1,33	0,94	0	probably_damaging	0,96	neutral	0,42	neutral	4,49	deleterious	-3,56	deleterious	-6,96	high_impact	4	neutral	0,7	neutral	0,51	deleterious	4,1	23,7	0,28	0,45	disease	0,66	disease	0,92	disease	0,63	disease	0,73	5	neutral	0,96	neutral	0,23	deleterious	2	deleterious	0,74	low_impact	-2,06	medium_impact	0,16	high_impact	2,45	0,53	0,8	4,15	8,74	N	0,41	N	0,98	disease_causing	0,86	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12749	12749	T	G	MI.20127	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	413	138	F	C	tTc/tGc	1,33	0,94	0	probably_damaging	0,98	neutral	0,18	neutral	4,47	deleterious	-5,12	deleterious	-6,87	high_impact	3,65	neutral	0,68	neutral	0,46	deleterious	4	23,6	0,32	0,5	disease	0,94	disease	0,94	disease	0,66	disease	0,83	7	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-2,35	medium_impact	-0,13	high_impact	2,13	0,36	0,8	4,15	8,74	N	0,41	N	0,95	disease_causing	0,91	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12750	12750	C	A	MI.20128	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	414	138	F	L	ttC/ttA	5,46	0,98	0	benign	0,08	neutral	0,68	neutral	4,89	neutral	0,51	deleterious	-4,56	neutral_impact	0,23	neutral	0,8	neutral	0,88	neutral	1,56	13,65	0,45	0,55	neutral	0,49	disease	0,79	neutral	0,45	disease	0,51	0	neutral	0,22	deleterious	0,8	neutral	-6	neutral	0,2	medium_impact	0,26	medium_impact	0,41	medium_impact	-0,99	0,78	0,85	4,15	8,74	N	0,45	N	0,44	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12750	12750	C	G	MI.20129	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	414	138	F	L	ttC/ttG	5,46	0,98	0	benign	0,08	neutral	0,68	neutral	4,89	neutral	0,51	deleterious	-4,56	neutral_impact	0,23	neutral	0,8	neutral	0,88	neutral	1,29	12,21	0,45	0,55	neutral	0,49	disease	0,79	neutral	0,45	disease	0,51	0	neutral	0,22	deleterious	0,8	neutral	-6	neutral	0,2	medium_impact	0,26	medium_impact	0,41	medium_impact	-0,99	0,78	0,85	4,15	8,74	N	0,45	N	0,44	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5967	5967	T	G	MI.2013	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	64	22	F	V	Ttc/Gtc	-0,34	0,55	0	probably_damaging	1	neutral	0,06	neutral	2,9	neutral	-2,79	neutral	-2,5	medium_impact	3,35	neutral	0,63	damaging	0,14	deleterious	3,83	23,4	0,24	0,55	neutral	0,31	disease	0,88	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,77	low_impact	-3,58	medium_impact	-0,47	medium_impact	1,99	0,59	0,9	2,92	6,69	N	0,29	N	0,84	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12751	12751	C	A	MI.20130	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	415	139	Q	K	Caa/Aaa	-4,4	0	0	probably_damaging	1	neutral	0,29	neutral	4,59	neutral	-2,99	deleterious	-3,95	high_impact	3,8	neutral	0,64	neutral	0,35	deleterious	3,88	23,5	0,47	0,55	disease	0,85	disease	0,95	disease	0,73	disease	0,84	7	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,02	high_impact	2,27	0,59	0,8	28,03	7,17	N	0,35	N	0,96	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12751	12751	C	G	MI.20131	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	415	139	Q	E	Caa/Gaa	-4,4	0	0	probably_damaging	1	neutral	0,28	neutral	4,59	neutral	-2,4	deleterious	-2,96	medium_impact	3,17	neutral	0,66	neutral	0,41	deleterious	3,06	22,4	0,48	0,55	disease	0,87	disease	0,9	disease	0,72	disease	0,81	6	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,01	medium_impact	1,69	0,65	0,8	28,03	7,17	N	0,3	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12752	12752	A	G	MI.20132	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	416	139	Q	R	cAa/cGa	2,94	0,98	0	probably_damaging	1	neutral	0,35	neutral	4,58	neutral	-2,94	deleterious	-3,95	high_impact	4,14	neutral	0,64	neutral	0,36	deleterious	3,43	23	0,47	0,55	disease	0,87	disease	0,94	disease	0,74	disease	0,85	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,08	high_impact	2,58	0,57	0,8	28,03	7,17	P	0,56	P	0,85	disease_causing	0,97	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12752	12752	A	T	MI.20133	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	416	139	Q	L	cAa/cTa	2,94	0,98	0	probably_damaging	1	neutral	0,68	neutral	4,86	neutral	1,71	deleterious	-6,91	neutral_impact	0,5	neutral	0,68	neutral	0,63	deleterious	3,8	23,4	0,39	0,5	neutral	0,36	disease	0,9	disease	0,61	disease	0,54	1	deleterious	1	neutral	0,34	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	0,41	medium_impact	-0,75	0,31	0,8	28,03	7,17	N	0,36	N	0,96	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12752	12752	A	C	MI.20134	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	416	139	Q	P	cAa/cCa	2,94	0,98	0	probably_damaging	1	neutral	0,21	neutral	4,57	deleterious	-3,77	deleterious	-5,92	medium_impact	2,79	neutral	0,61	neutral	0,37	deleterious	3,3	22,9	0,25	0,45	disease	0,91	disease	0,95	disease	0,74	disease	0,84	7	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,91	low_impact	-3,6	medium_impact	-0,09	medium_impact	1,35	0,59	0,8	28,03	7,17	N	0,41	N	0,95	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12753	12753	A	T	MI.20135	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	417	139	Q	H	caA/caT	6,61	0,99	0	probably_damaging	1	neutral	0,53	neutral	4,57	deleterious	-3,26	deleterious	-4,93	high_impact	3,8	neutral	0,68	neutral	0,32	deleterious	3,53	23,1	0,54	0,6	disease	0,91	disease	0,91	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,26	high_impact	2,27	0,79	0,85	28,03	7,17	P	0,59	P	0,94	disease_causing	0,99	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12753	12753	A	C	MI.20136	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	417	139	Q	H	caA/caC	6,61	0,99	0	probably_damaging	1	neutral	0,53	neutral	4,57	deleterious	-3,26	deleterious	-4,93	high_impact	3,8	neutral	0,68	neutral	0,32	deleterious	3,39	23	0,54	0,6	disease	0,91	disease	0,91	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,26	high_impact	2,27	0,79	0,85	28,03	7,17	P	0,57	P	0,94	disease_causing	0,99	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12754	12754	C	G	MI.20137	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	418	140	L	V	Ctg/Gtg	-1,19	0	0	possibly_damaging	0,81	neutral	0,52	neutral	4,57	neutral	-2,87	deleterious	-2,96	medium_impact	3,01	neutral	0,66	neutral	0,62	deleterious	3,32	22,9	0,39	0,5	disease	0,59	disease	0,8	disease	0,6	disease	0,66	3	neutral	0,79	neutral	0,36	NA	0	deleterious	0,79	low_impact	-1,34	medium_impact	0,25	medium_impact	1,55	0,69	0,85	9,29	7,17	N	0,26	N	0,52	polymorphism	0,88	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12754	12754	C	A	MI.20138	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	418	140	L	M	Ctg/Atg	-1,19	0	0	probably_damaging	0,98	neutral	0,24	neutral	4,68	neutral	-1,61	neutral	-1,97	low_impact	1,53	neutral	0,6	neutral	0,48	deleterious	3,78	23,4	0,31	0,45	disease	0,58	disease	0,63	disease	0,58	neutral	0,5	0	deleterious	0,98	neutral	0,13	neutral	-2	deleterious	0,73	low_impact	-2,35	medium_impact	-0,04	medium_impact	0,2	0,77	0,85	9,29	7,17	N	0,33	N	0,56	polymorphism	0,91	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12755	12755	T	A	MI.20139	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	419	140	L	Q	cTg/cAg	0,18	0,02	0	probably_damaging	0,99	neutral	0,31	neutral	4,49	deleterious	-5,77	deleterious	-5,92	high_impact	4,72	damaging	0,58	neutral	0,35	deleterious	4,25	23,9	0,16	0,45	disease	0,92	disease	0,9	disease	0,6	disease	0,79	6	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-2,64	medium_impact	0,04	high_impact	3,11	0,77	0,85	9,29	7,17	P	0,59	P	0,95	disease_causing	0,98	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5968	5968	T	C	MI.2014	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	65	22	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-2,89	deleterious	-3,11	medium_impact	3,13	neutral	0,74	damaging	0,17	deleterious	4,15	23,8	0,25	0,55	neutral	0,36	disease	0,87	disease	0,57	disease	0,69	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	medium_impact	1,79	0,64	0,9	2,92	6,69	N	0,49	N	0,84	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12755	12755	T	C	MI.20140	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	419	140	L	P	cTg/cCg	0,18	0,02	0	probably_damaging	0,99	neutral	0,21	neutral	4,45	deleterious	-6,34	deleterious	-6,91	high_impact	4,72	damaging	0,54	neutral	0,29	deleterious	3,84	23,4	0,15	0,45	disease	0,96	disease	0,93	disease	0,72	disease	0,83	7	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,91	low_impact	-2,64	medium_impact	-0,09	high_impact	3,11	0,63	0,8	9,29	7,17	P	0,54	P	0,94	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12755	12755	T	G	MI.20141	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	419	140	L	R	cTg/cGg	0,18	0,02	0	probably_damaging	0,98	neutral	0,35	neutral	4,46	deleterious	-5,78	deleterious	-5,92	high_impact	4,72	damaging	0,56	neutral	0,31	deleterious	4,11	23,8	0,14	0,4	disease	0,94	disease	0,95	disease	0,71	disease	0,83	7	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,92	low_impact	-2,35	medium_impact	0,08	high_impact	3,11	0,5	0,8	9,29	7,17	P	0,58	P	0,97	disease_causing	0,98	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12757	12757	T	C	MI.20142	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	421	141	F	L	Ttc/Ctc	-6,24	0	0	benign	0,12	neutral	0,77	neutral	4,45	neutral	-2,07	deleterious	-5,66	low_impact	1	damaging	0,59	neutral	0,56	deleterious	3,89	23,5	0,34	0,5	disease	0,63	disease	0,86	disease	0,6	disease	0,53	1	neutral	0,12	deleterious	0,83	neutral	-6	deleterious	0,79	medium_impact	0,08	medium_impact	0,52	medium_impact	-0,29	0,63	0,8	22,55	7,17	N	0,24	N	0,48	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12757	12757	T	A	MI.20143	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	421	141	F	I	Ttc/Atc	-6,24	0	0	possibly_damaging	0,81	neutral	0,46	neutral	4,34	deleterious	-3,71	deleterious	-5,71	medium_impact	2,69	damaging	0,6	neutral	0,58	deleterious	4,3	24	0,22	0,45	disease	0,74	disease	0,93	disease	0,63	disease	0,72	4	neutral	0,8	neutral	0,33	NA	0	deleterious	0,84	low_impact	-1,34	medium_impact	0,19	medium_impact	1,25	0,57	0,8	22,55	7,17	N	0,29	N	0,86	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12757	12757	T	G	MI.20144	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	421	141	F	V	Ttc/Gtc	-6,24	0	0	possibly_damaging	0,81	neutral	0,58	neutral	4,39	deleterious	-3,43	deleterious	-6,7	high_impact	3,53	damaging	0,57	neutral	0,47	deleterious	3,96	23,6	0,27	0,45	disease	0,76	disease	0,94	disease	0,68	disease	0,77	5	neutral	0,78	neutral	0,39	deleterious	1	deleterious	0,83	low_impact	-1,34	medium_impact	0,31	high_impact	2,02	0,54	0,8	22,55	7,17	N	0,29	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12758	12758	T	C	MI.20145	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	422	141	F	S	tTc/tCc	4,54	1	0	probably_damaging	0,97	neutral	0,62	neutral	4,31	deleterious	-5,09	deleterious	-7,74	high_impact	4,68	neutral	0,63	neutral	0,55	deleterious	4,17	23,8	0,23	0,45	disease	0,89	disease	0,93	disease	0,66	disease	0,79	6	neutral	0,97	neutral	0,33	deleterious	2	deleterious	0,86	low_impact	-2,18	medium_impact	0,35	high_impact	3,07	0,47	0,8	22,55	7,17	P	0,61	P	0,98	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12758	12758	T	G	MI.20146	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	422	141	F	C	tTc/tGc	4,54	1	0	probably_damaging	0,99	neutral	0,19	neutral	4,32	deleterious	-6,43	deleterious	-7,71	high_impact	4,68	damaging	0,6	neutral	0,46	deleterious	4,03	23,6	0,25	0,45	disease	0,68	disease	0,94	disease	0,7	disease	0,85	7	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-2,64	medium_impact	-0,12	high_impact	3,07	0,31	0,8	22,55	7,17	P	0,53	P	0,96	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12758	12758	T	A	MI.20147	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	422	141	F	Y	tTc/tAc	4,54	1	0	probably_damaging	0,92	neutral	1	neutral	4,74	neutral	-0,59	deleterious	-2,91	low_impact	1,93	neutral	0,61	neutral	0,47	deleterious	4,18	23,8	0,26	0,45	neutral	0,47	disease	0,9	disease	0,62	disease	0,71	4	neutral	0,92	deleterious	0,54	neutral	-2	deleterious	0,79	low_impact	-1,75	high_impact	1,89	medium_impact	0,56	0,58	0,8	22,55	7,17	N	0,43	N	0,71	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12759	12759	C	A	MI.20148	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	423	141	F	L	ttC/ttA	7,3	1	0	benign	0,12	neutral	0,77	neutral	4,45	neutral	-2,07	deleterious	-5,66	low_impact	1	damaging	0,59	neutral	0,56	deleterious	4,56	24,4	0,34	0,5	disease	0,63	disease	0,86	disease	0,6	disease	0,53	1	neutral	0,12	deleterious	0,83	neutral	-6	deleterious	0,79	medium_impact	0,08	medium_impact	0,52	medium_impact	-0,29	0,63	0,8	22,55	7,17	N	0,43	N	0,48	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12759	12759	C	G	MI.20149	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	423	141	F	L	ttC/ttG	7,3	1	0	benign	0,12	neutral	0,77	neutral	4,45	neutral	-2,07	deleterious	-5,66	low_impact	1	damaging	0,59	neutral	0,56	deleterious	4,23	23,9	0,34	0,5	disease	0,63	disease	0,86	disease	0,6	disease	0,53	1	neutral	0,12	deleterious	0,83	neutral	-6	deleterious	0,79	medium_impact	0,08	medium_impact	0,52	medium_impact	-0,29	0,63	0,8	22,55	7,17	N	0,43	N	0,48	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5968	5968	T	G	MI.2015	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	65	22	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-5,27	deleterious	-3,05	high_impact	4,63	damaging	0,57	damaging	0,15	deleterious	3,94	23,6	0,24	0,55	disease	0,71	disease	0,9	disease	0,64	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,18	0,38	0,9	2,92	6,69	P	0,52	P	0,91	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12760	12760	A	C	MI.20150	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	424	142	I	L	Atc/Ctc	-6,01	0	0	probably_damaging	1	neutral	1	neutral	4,69	neutral	0,01	neutral	-1,86	low_impact	1,08	neutral	0,64	damaging	0,15	deleterious	3,68	23,3	0,42	0,55	neutral	0,36	disease	0,74	disease	0,51	disease	0,52	0	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,67	low_impact	-3,6	high_impact	1,89	medium_impact	-0,22	0,66	0,8	4,31	11,73	N	0,21	N	0,86	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12760	12760	A	G	MI.20151	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	424	142	I	V	Atc/Gtc	-6,01	0	0	probably_damaging	1	neutral	0,66	neutral	4,51	neutral	0,83	neutral	-0,93	neutral_impact	0,77	neutral	0,78	neutral	0,66	deleterious	2,93	22	0,49	0,55	neutral	0,36	neutral	0,5	neutral	0,42	neutral	0,43	1	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,63	low_impact	-3,6	medium_impact	0,39	medium_impact	-0,5	0,61	0,8	4,31	11,73	N	0,23	N	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12760	12760	A	T	MI.20152	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	424	142	I	F	Atc/Ttc	-6,01	0	0	probably_damaging	1	neutral	0,86	neutral	4,44	neutral	-1,26	deleterious	-3,83	medium_impact	2,04	neutral	0,62	damaging	0,09	deleterious	3,66	23,2	0,28	0,45	disease	0,65	disease	0,82	disease	0,66	disease	0,57	1	deleterious	1	neutral	0,43	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,67	medium_impact	0,66	0,79	0,85	4,31	11,73	N	0,15	N	0,96	polymorphism	0,97	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12761	12761	T	C	MI.20153	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	425	142	I	T	aTc/aCc	3,85	0,99	0	probably_damaging	1	neutral	0,72	neutral	4,37	deleterious	-3,02	deleterious	-4,8	medium_impact	3,39	damaging	0,6	damaging	0,11	deleterious	3,35	22,9	0,31	0,45	disease	0,78	disease	0,86	disease	0,62	disease	0,72	4	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,46	medium_impact	1,89	0,63	0,8	4,31	11,73	N	0,37	N	0,96	disease_causing	0,97	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12761	12761	T	A	MI.20154	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	425	142	I	N	aTc/aAc	3,85	0,99	0	probably_damaging	1	neutral	0,71	neutral	4,34	deleterious	-5,07	deleterious	-6,75	high_impact	4,43	damaging	0,59	damaging	0,11	deleterious	4,4	24,1	0,19	0,45	disease	0,82	disease	0,91	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,45	high_impact	2,84	0,6	0,8	4,31	11,73	N	0,48	N	0,99	disease_causing	0,99	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12761	12761	T	G	MI.20155	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	425	142	I	S	aTc/aGc	3,85	0,99	0	probably_damaging	1	neutral	0,85	neutral	4,36	deleterious	-3,61	deleterious	-5,76	high_impact	4,43	neutral	0,62	damaging	0,12	deleterious	4,22	23,9	0,21	0,45	disease	0,84	disease	0,91	disease	0,62	disease	0,74	5	deleterious	1	neutral	0,43	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,65	high_impact	2,84	0,58	0,8	4,31	11,73	N	0,46	N	0,96	disease_causing	0,99	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12762	12762	C	A	MI.20156	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	426	142	I	M	atC/atA	5,69	1	0	probably_damaging	1	neutral	0,56	neutral	4,46	neutral	-2,46	deleterious	-2,69	medium_impact	2,65	neutral	0,66	neutral	0,75	deleterious	3,72	23,3	0,29	0,45	disease	0,71	disease	0,76	disease	0,56	disease	0,63	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,29	medium_impact	1,22	0,76	0,85	4,31	11,73	N	0,4	N	0,76	disease_causing	0,99	0,07	rs28379632	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12762	12762	C	G	MI.20157	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	426	142	I	M	atC/atG	5,69	1	0	probably_damaging	1	neutral	0,56	neutral	4,46	neutral	-2,46	deleterious	-2,69	medium_impact	2,65	neutral	0,66	neutral	0,75	deleterious	3,22	22,7	0,29	0,45	disease	0,71	disease	0,76	disease	0,56	disease	0,63	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,29	medium_impact	1,22	0,76	0,85	4,31	11,73	N	0,43	N	0,76	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12763	12763	G	A	MI.20158	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	427	143	G	S	Ggc/Agc	-5,55	0	0	probably_damaging	1	neutral	0,46	neutral	4,47	neutral	-2,92	deleterious	-5,87	high_impact	3,98	damaging	0,39	damaging	0,08	deleterious	4,05	23,7	0,34	0,5	disease	0,72	disease	0,92	disease	0,65	disease	0,73	5	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,19	high_impact	2,43	0,81	0,85	28,03	7,18	N	0,45	N	1	disease_causing	0,54	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12763	12763	G	T	MI.20159	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	427	143	G	C	Ggc/Tgc	-5,55	0	0	probably_damaging	1	neutral	0,18	neutral	4,33	deleterious	-4,4	deleterious	-8,84	high_impact	3,92	damaging	0,42	damaging	0,05	deleterious	4	23,6	0,17	0,45	disease	0,81	disease	0,96	disease	0,68	disease	0,79	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,13	high_impact	2,38	0,55	0,8	28,03	7,18	N	0,36	N	0,97	disease_causing	0,83	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5968	5968	T	A	MI.2016	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	65	22	F	Y	tTc/tAc	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,74	deleterious	-3,19	neutral	-1,19	high_impact	3,54	neutral	0,66	damaging	0,14	deleterious	4,18	23,8	0,31	0,55	disease	0,6	disease	0,83	disease	0,56	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,35	low_impact	-1,48	high_impact	2,17	0,7	0,9	2,92	6,69	P	0,52	P	0,59	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12763	12763	G	C	MI.20160	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	427	143	G	R	Ggc/Cgc	-5,55	0	0	probably_damaging	1	neutral	0,43	neutral	4,35	deleterious	-5,2	deleterious	-7,86	high_impact	4,32	damaging	0,47	damaging	0,06	deleterious	3,78	23,4	0,16	0,45	disease	0,61	disease	0,96	disease	0,77	disease	0,87	7	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,17	high_impact	2,74	0,7	0,85	28,03	7,18	N	0,46	N	1	disease_causing	0,71	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12764	12764	G	A	MI.20161	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	428	143	G	D	gGc/gAc	5,92	1	0	probably_damaging	1	neutral	0,24	neutral	4,33	deleterious	-6,4	deleterious	-6,87	high_impact	5,01	damaging	0,51	damaging	0,07	deleterious	3,71	23,3	0,17	0,45	disease	0,95	disease	0,94	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,04	high_impact	3,37	0,54	0,8	28,03	7,18	P	0,62	P	0,95	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12764	12764	G	C	MI.20162	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	428	143	G	A	gGc/gCc	5,92	1	0	probably_damaging	1	neutral	0,55	neutral	4,44	neutral	-1,31	deleterious	-5,89	high_impact	3,54	damaging	0,44	damaging	0,1	deleterious	3,06	22,4	0,37	0,5	disease	0,51	disease	0,88	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,28	high_impact	2,03	0,79	0,85	28,03	7,18	P	0,55	P	0,79	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12764	12764	G	T	MI.20163	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	428	143	G	V	gGc/gTc	5,92	1	0	probably_damaging	1	neutral	0,59	neutral	4,41	neutral	-2,7	deleterious	-8,85	high_impact	4,12	damaging	0,35	damaging	0,05	deleterious	3,69	23,3	0,18	0,45	neutral	0,47	disease	0,95	disease	0,67	disease	0,79	6	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,32	high_impact	2,56	0,5	0,8	28,03	7,18	P	0,61	P	0,98	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12766	12766	T	C	MI.20164	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	430	144	W	R	Tga/Cga	-9,68	0	0	probably_damaging	1	neutral	0,36	neutral	4,36	deleterious	-6,21	deleterious	-13,81	high_impact	5,2	damaging	0,48	damaging	0,03	deleterious	3,54	23,1	0,26	0,45	disease	0,93	disease	0,95	disease	0,79	disease	0,85	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,1	high_impact	3,55	0,33	0,8	28,03	7,21	P	0,53	P	0,97	polymorphism	0,54	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12766	12766	T	G	MI.20165	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	430	144	W	G	Tga/Gga	-9,68	0	0	probably_damaging	1	neutral	0,4	neutral	4,36	deleterious	-6,34	deleterious	-12,83	high_impact	5,2	damaging	0,44	damaging	0,04	deleterious	3,86	23,4	0,22	0,45	disease	0,94	disease	0,89	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,14	high_impact	3,55	0,3	0,8	28,03	7,21	P	0,51	P	0,97	disease_causing	0,7	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12767	12767	G	T	MI.20166	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	431	144	W	L	tGa/tTa	7,3	1	0	probably_damaging	1	neutral	0,71	neutral	4,63	neutral	-1,91	deleterious	-12,83	medium_impact	3,29	damaging	0,45	damaging	0,03	deleterious	4,18	23,8	0,25	0,45	disease	0,55	disease	0,91	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,45	medium_impact	1,8	0,32	0,8	28,03	7,21	N	0,48	N	0,97	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12767	12767	G	C	MI.20167	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	431	144	W	S	tGa/tCa	7,3	1	0	probably_damaging	1	neutral	0,44	neutral	4,37	deleterious	-5,12	deleterious	-13,81	high_impact	5,2	damaging	0,46	damaging	0,05	deleterious	3,92	23,5	0,21	0,45	disease	0,87	disease	0,94	disease	0,73	disease	0,84	7	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,18	high_impact	3,55	0,27	0,8	28,03	7,21	P	0,54	P	0,95	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12768	12768	A	C	MI.20168	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	432	144	W	C	tgA/tgC	9,13	1	0	probably_damaging	1	neutral	0,18	neutral	4,36	deleterious	-6,58	deleterious	-12,83	high_impact	5,2	damaging	0,42	damaging	0,03	deleterious	3,98	23,6	0,27	0,45	disease	0,95	disease	0,95	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,13	high_impact	3,55	0,34	0,8	28,03	7,21	P	0,56	P	0,98	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12768	12768	A	T	MI.20169	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	432	144	W	C	tgA/tgT	9,13	1	0	probably_damaging	1	neutral	0,18	neutral	4,36	deleterious	-6,58	deleterious	-12,83	high_impact	5,2	damaging	0,42	damaging	0,03	deleterious	4,08	23,7	0,27	0,45	disease	0,95	disease	0,95	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,13	high_impact	3,55	0,34	0,8	28,03	7,21	P	0,57	P	0,98	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5969	5969	C	A	MI.2017	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	66	22	F	L	ttC/ttA	5,68	1	0	probably_damaging	0,98	neutral	0,21	neutral	2,91	neutral	-2,6	neutral	-1,98	low_impact	1,35	damaging	0,51	damaging	0,18	deleterious	3,18	22,7	0,32	0,55	neutral	0,19	disease	0,72	neutral	0,41	disease	0,56	1	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,72	low_impact	-2,35	medium_impact	-0,13	medium_impact	0,15	0,56	0,9	2,92	6,69	P	0,58	P	0,83	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12769	12769	G	C	MI.20170	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	433	145	E	Q	Gag/Cag	0,18	0,96	0	probably_damaging	1	neutral	0,29	neutral	3,14	deleterious	-6,46	deleterious	-2,95	high_impact	5,04	damaging	0,29	damaging	0,15	deleterious	3,32	22,9	0,24	0,45	disease	0,7	disease	0,83	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,02	high_impact	3,4	0,71	0,85	26,7	7,22	P	0,86	P	0,89	disease_causing	0,99	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12769	12769	G	A	MI.20171	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	433	145	E	K	Gag/Aag	0,18	0,96	0	probably_damaging	1	neutral	0,29	neutral	3,14	deleterious	-6,47	deleterious	-3,92	high_impact	4,14	damaging	0,3	damaging	0,13	deleterious	4,38	24,1	0,19	0,45	disease	0,88	disease	0,94	disease	0,78	disease	0,86	7	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,02	high_impact	2,58	0,73	0,85	26,7	7,22	P	0,73	P	0,99	disease_causing	1	0,42	rs879058074	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12770	12770	A	C	MI.20172	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	434	145	E	A	gAg/gCg	8,9	1	0	probably_damaging	1	neutral	0,52	neutral	3,14	deleterious	-6,58	deleterious	-5,91	high_impact	4,69	damaging	0,31	damaging	0,13	deleterious	3,6	23,2	0,2	0,45	disease	0,91	disease	0,86	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,25	high_impact	3,08	0,59	0,8	26,7	7,22	P	0,81	P	0,75	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12770	12770	A	G	MI.20173	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	434	145	E	G	gAg/gGg	8,9	1	0	probably_damaging	1	neutral	0,41	neutral	3,18	deleterious	-5,24	deleterious	-6,89	high_impact	3,8	damaging	0,18	damaging	0,16	deleterious	4,15	23,8	0,24	0,45	disease	0,9	disease	0,83	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,15	high_impact	2,27	0,38	0,8	26,7	7,22	P	0,91	P	0,51	disease_causing_automatic	1	0,42	rs267606894	Pathogenic	Juvenile_myopathy,_encephalopathy,_lactic_acidosis_AND_stroke	RCV000010339.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	A12770G	MELAS	-	+	Reported	4
chrM	12770	12770	A	T	MI.20174	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	434	145	E	V	gAg/gTg	8,9	1	0	probably_damaging	1	neutral	0,53	neutral	3,12	deleterious	-8,28	deleterious	-6,89	high_impact	5,04	damaging	0,22	damaging	0,1	deleterious	4,09	23,7	0,19	0,45	disease	0,96	disease	0,93	disease	0,76	disease	0,83	7	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,26	high_impact	3,4	0,63	0,8	26,7	7,22	P	0,8	P	0,81	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12771	12771	G	C	MI.20175	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	435	145	E	D	gaG/gaC	8,44	1	0,1	probably_damaging	1	neutral	0,2	neutral	3,28	deleterious	-3,93	deleterious	-2,96	medium_impact	2,42	damaging	0,4	damaging	0,13	deleterious	3,62	23,2	0,28	0,45	disease	0,83	disease	0,81	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	-0,1	medium_impact	1,01	0,76	0,85	26,7	7,22	P	0,71	P	0,86	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12771	12771	G	T	MI.20176	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	435	145	E	D	gaG/gaT	8,44	1	0,1	probably_damaging	1	neutral	0,2	neutral	3,28	deleterious	-3,93	deleterious	-2,96	medium_impact	2,42	damaging	0,4	damaging	0,13	deleterious	3,78	23,4	0,28	0,45	disease	0,83	disease	0,81	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	-0,1	medium_impact	1,01	0,76	0,85	26,7	7,22	P	0,71	P	0,86	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12772	12772	G	A	MI.20177	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	436	146	G	S	Ggc/Agc	-2,34	0	0	probably_damaging	1	neutral	0,89	neutral	4,58	neutral	-2,87	deleterious	-5,87	high_impact	4,56	damaging	0,5	damaging	0,11	deleterious	4,16	23,8	0,35	0,5	disease	0,8	disease	0,88	disease	0,53	disease	0,72	4	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,73	high_impact	2,96	0,74	0,85	29,35	7,17	N	0,38	N	1	disease_causing	1	0,2	rs879130607	.	.	.	.	.	COSM1155529	.	.	.	.	.	.	.	.
chrM	12772	12772	G	C	MI.20178	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	436	146	G	R	Ggc/Cgc	-2,34	0	0	probably_damaging	1	neutral	0,68	neutral	4,54	deleterious	-4,53	deleterious	-7,86	high_impact	4,91	neutral	0,67	damaging	0,06	deleterious	3,89	23,5	0,06	0,35	disease	0,92	disease	0,95	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,41	high_impact	3,28	0,62	0,8	29,35	7,17	P	0,62	P	1	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12772	12772	G	T	MI.20179	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	436	146	G	C	Ggc/Tgc	-2,34	0	0	probably_damaging	1	neutral	0,2	neutral	4,55	deleterious	-4,39	deleterious	-8,84	high_impact	4,56	neutral	0,63	damaging	0,06	deleterious	4,03	23,7	0,11	0,4	disease	0,83	disease	0,94	disease	0,64	disease	0,77	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,1	high_impact	2,96	0,68	0,85	29,35	7,17	N	0,44	N	0,97	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5969	5969	C	G	MI.2018	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	66	22	F	L	ttC/ttG	5,68	1	0	probably_damaging	0,98	neutral	0,21	neutral	2,91	neutral	-2,6	neutral	-1,98	low_impact	1,35	damaging	0,51	damaging	0,18	deleterious	2,9	21,8	0,32	0,55	neutral	0,19	disease	0,72	neutral	0,41	disease	0,56	1	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,72	low_impact	-2,35	medium_impact	-0,13	medium_impact	0,15	0,56	0,9	2,92	6,69	P	0,58	P	0,83	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12773	12773	G	A	MI.20180	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	437	146	G	D	gGc/gAc	7,3	1	0	probably_damaging	1	neutral	0,67	neutral	4,52	deleterious	-5,45	deleterious	-6,87	high_impact	4,91	neutral	0,75	damaging	0,07	deleterious	3,69	23,3	0,08	0,35	disease	0,68	disease	0,93	disease	0,71	disease	0,8	6	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,4	high_impact	3,28	0,5	0,8	29,35	7,17	P	0,67	P	0,95	disease_causing	1	0,39	.	.	.	.	.	.	COSM1132240	.	.	.	.	.	.	.	.
chrM	12773	12773	G	C	MI.20181	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	437	146	G	A	gGc/gCc	7,3	1	0	probably_damaging	1	neutral	0,97	neutral	4,64	neutral	-0,72	deleterious	-5,89	medium_impact	2,56	damaging	0,52	damaging	0,25	deleterious	3,03	22,3	0,48	0,55	disease	0,64	disease	0,83	disease	0,57	disease	0,53	1	deleterious	1	deleterious	0,49	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	1,07	medium_impact	1,14	0,77	0,85	29,35	7,17	N	0,43	N	0,79	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12773	12773	G	T	MI.20182	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	437	146	G	V	gGc/gTc	7,3	1	0	probably_damaging	1	neutral	0,64	neutral	4,67	neutral	-0,44	deleterious	-8,85	medium_impact	3,46	damaging	0,56	damaging	0,06	deleterious	3,72	23,3	0,11	0,4	disease	0,68	disease	0,94	disease	0,6	disease	0,77	5	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,37	medium_impact	1,96	0,67	0,85	29,35	7,17	N	0,38	N	0,98	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12775	12775	G	C	MI.20183	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	439	147	V	L	Gta/Cta	-8,53	0	0	possibly_damaging	0,61	neutral	0,69	neutral	4,69	neutral	-1,06	deleterious	-2,77	medium_impact	2,04	damaging	0,33	neutral	0,44	deleterious	3,52	23,1	0,53	0,6	neutral	0,43	disease	0,82	disease	0,61	disease	0,64	3	neutral	0,53	deleterious	0,54	NA	0	deleterious	0,75	medium_impact	-0,93	medium_impact	0,42	medium_impact	0,66	0,61	0,8	9,29	16,45	P	0,59	P	0,77	polymorphism	0,98	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12775	12775	G	A	MI.20184	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	439	147	V	M	Gta/Ata	-8,53	0	0	benign	0,4	neutral	0,26	neutral	4,48	neutral	-0,79	deleterious	-2,63	medium_impact	2,37	damaging	0,49	neutral	0,63	deleterious	3,57	23,2	0,52	0,6	disease	0,61	disease	0,81	disease	0,58	disease	0,62	2	neutral	0,7	neutral	0,43	neutral	-3	deleterious	0,74	medium_impact	-0,58	medium_impact	-0,02	medium_impact	0,96	0,75	0,85	9,29	16,45	N	0,4	N	0,95	polymorphism	0,98	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12775	12775	G	T	MI.20185	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	439	147	V	L	Gta/Tta	-8,53	0	0	possibly_damaging	0,61	neutral	0,69	neutral	4,69	neutral	-1,06	deleterious	-2,77	medium_impact	2,04	damaging	0,33	neutral	0,44	deleterious	3,64	23,2	0,53	0,6	neutral	0,43	disease	0,82	disease	0,61	disease	0,64	3	neutral	0,53	deleterious	0,54	NA	0	deleterious	0,75	medium_impact	-0,93	medium_impact	0,42	medium_impact	0,66	0,61	0,8	9,29	16,45	P	0,6	P	0,77	polymorphism	0,98	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12776	12776	T	G	MI.20186	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	440	147	V	G	gTa/gGa	7,3	1	0	probably_damaging	0,95	neutral	0,42	neutral	4,49	deleterious	-4,4	deleterious	-6,75	high_impact	4,75	damaging	0,41	neutral	0,51	deleterious	3,74	23,3	0,28	0,45	disease	0,92	disease	0,84	disease	0,68	disease	0,81	6	neutral	0,95	neutral	0,24	deleterious	2	deleterious	0,81	low_impact	-1,96	medium_impact	0,16	high_impact	3,14	0,41	0,8	9,29	16,45	P	0,79	P	0,89	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12776	12776	T	A	MI.20187	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	440	147	V	E	gTa/gAa	7,3	1	0	probably_damaging	0,97	neutral	0,3	neutral	4,49	deleterious	-4,14	deleterious	-5,77	high_impact	4,75	damaging	0,43	neutral	0,42	deleterious	4,56	24,4	0,18	0,45	disease	0,79	disease	0,91	disease	0,76	disease	0,81	6	neutral	0,97	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-2,18	medium_impact	0,03	high_impact	3,14	0,46	0,8	9,29	16,45	P	0,8	P	0,97	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12776	12776	T	C	MI.20188	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	440	147	V	A	gTa/gCa	7,3	1	0	possibly_damaging	0,73	neutral	0,51	neutral	4,5	neutral	-2,15	deleterious	-3,85	high_impact	4,4	damaging	0,36	neutral	0,51	deleterious	3,48	23,1	0,48	0,55	disease	0,67	disease	0,76	disease	0,64	disease	0,66	3	neutral	0,7	neutral	0,39	deleterious	1	deleterious	0,78	low_impact	-1,16	medium_impact	0,24	high_impact	2,82	0,31	0,8	9,29	16,45	P	0,8	P	0,52	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12778	12778	G	C	MI.20189	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	442	148	G	R	Gga/Cga	-11,97	0	0	probably_damaging	1	neutral	0,36	neutral	4,39	deleterious	-4,27	deleterious	-7,89	high_impact	4,76	damaging	0,33	damaging	0,22	deleterious	3,83	23,4	0,07	0,35	disease	0,82	disease	0,94	disease	0,8	disease	0,89	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,1	high_impact	3,15	0,77	0,85	29,85	7,26	P	0,67	P	1	polymorphism	0,82	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5970	5970	G	C	MI.2019	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	67	23	G	R	Ggc/Cgc	-3,81	0	0	probably_damaging	0,98	deleterious	0	neutral	2,65	deleterious	-5,31	deleterious	-3,55	high_impact	4,04	damaging	0,57	damaging	0,19	deleterious	3,75	23,3	0,09	0,55	disease	0,51	disease	0,93	disease	0,71	disease	0,85	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,35	low_impact	-1,48	high_impact	2,63	0,7	0,9	3,31	7,62	N	0,32	N	0,88	disease_causing	0,97	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12778	12778	G	T	MI.20190	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	442	148	G	W	Gga/Tga	-11,97	0	0	probably_damaging	1	neutral	0,2	neutral	4,36	deleterious	-6,68	deleterious	-7,89	high_impact	5,11	damaging	0,33	damaging	0,21	deleterious	4,28	24	0,12	0,4	disease	0,98	disease	0,95	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,1	high_impact	3,47	0,48	0,8	29,85	7,26	P	0,58	P	1	polymorphism	0,73	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12779	12779	G	A	MI.20191	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	443	148	G	E	gGa/gAa	5,92	1	0	probably_damaging	1	neutral	0,29	neutral	4,41	deleterious	-3,65	deleterious	-7,89	high_impact	5,11	damaging	0,26	damaging	0,25	deleterious	3,81	23,4	0,1	0,4	disease	0,74	disease	0,93	disease	0,78	disease	0,83	7	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,02	high_impact	3,47	0,75	0,85	29,85	7,26	P	0,9	P	1	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12779	12779	G	T	MI.20192	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	443	148	G	V	gGa/gTa	5,92	1	0	probably_damaging	1	neutral	0,53	neutral	4,42	neutral	-2,83	deleterious	-8,88	high_impact	5,11	damaging	0,23	damaging	0,27	deleterious	3,67	23,2	0,11	0,4	disease	0,79	disease	0,94	disease	0,7	disease	0,8	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,26	high_impact	3,47	0,61	0,8	29,85	7,26	P	0,88	P	0,98	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12779	12779	G	C	MI.20193	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	443	148	G	A	gGa/gCa	5,92	1	0	probably_damaging	1	neutral	0,52	neutral	4,43	neutral	-2,05	deleterious	-5,92	high_impact	4,76	damaging	0,35	neutral	0,38	deleterious	3,03	22,3	0,44	0,55	disease	0,75	disease	0,86	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,25	high_impact	3,15	0,8	0,85	29,85	7,26	P	0,83	P	0,79	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12781	12781	A	G	MI.20194	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	445	149	I	V	Att/Gtt	-3,26	0	0	probably_damaging	1	neutral	0,57	neutral	4,61	neutral	-0,72	neutral	-0,97	low_impact	0,94	neutral	0,81	neutral	0,67	deleterious	2,95	22,1	0,59	0,65	disease	0,57	neutral	0,4	disease	0,6	disease	0,61	2	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,63	low_impact	-3,6	medium_impact	0,3	medium_impact	-0,34	0,64	0,8	10,28	7,1	N	0,26	N	0,74	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12781	12781	A	T	MI.20195	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	445	149	I	F	Att/Ttt	-3,26	0	0	probably_damaging	1	neutral	0,77	neutral	4,54	neutral	-2,99	deleterious	-3,92	low_impact	1,45	neutral	0,69	neutral	0,38	deleterious	3,77	23,4	0,37	0,5	disease	0,87	disease	0,74	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,39	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,52	medium_impact	0,12	0,73	0,85	10,28	7,1	N	0,19	N	0,96	disease_causing	0,53	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12781	12781	A	C	MI.20196	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	445	149	I	L	Att/Ctt	-3,26	0	0	probably_damaging	1	neutral	0,73	neutral	4,84	neutral	1,06	neutral	-1,95	neutral_impact	0,5	neutral	0,69	neutral	0,67	deleterious	3,73	23,3	0,42	0,55	neutral	0,37	neutral	0,42	disease	0,62	neutral	0,43	1	deleterious	1	neutral	0,37	neutral	-2	deleterious	0,62	low_impact	-3,6	medium_impact	0,47	medium_impact	-0,75	0,75	0,85	10,28	7,1	N	0,29	N	0,86	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12782	12782	T	C	MI.20197	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	446	149	I	T	aTt/aCt	6,84	1	0	probably_damaging	1	neutral	0,39	neutral	4,52	deleterious	-3,65	deleterious	-4,9	high_impact	4,21	neutral	0,71	neutral	0,39	deleterious	3,41	23	0,5	0,6	disease	0,85	disease	0,66	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,13	high_impact	2,64	0,65	0,8	10,28	7,1	P	0,6	P	0,96	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12782	12782	T	A	MI.20198	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	446	149	I	N	aTt/aAt	6,84	1	0	probably_damaging	1	neutral	0,33	neutral	4,44	deleterious	-5,38	deleterious	-6,87	high_impact	3,87	neutral	0,68	neutral	0,4	deleterious	4,49	24,3	0,34	0,5	disease	0,94	disease	0,82	disease	0,69	disease	0,82	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,06	high_impact	2,33	0,54	0,8	10,28	7,1	P	0,56	P	0,99	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12782	12782	T	G	MI.20199	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	446	149	I	S	aTt/aGt	6,84	1	0	probably_damaging	1	neutral	0,45	neutral	4,47	deleterious	-3,59	deleterious	-5,88	high_impact	4,21	neutral	0,73	neutral	0,42	deleterious	4,23	23,9	0,3	0,45	disease	0,62	disease	0,78	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,74	low_impact	-3,6	medium_impact	0,18	high_impact	2,64	0,48	0,8	10,28	7,1	P	0,55	P	0,96	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	T12782G	LHON	-	+	Reported	1
chrM	8620	8620	C	A	MI.202	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	94	32	P	T	Ccc/Acc	-6,35	0	0	probably_damaging	1	neutral	0,14	neutral	4,53	neutral	2,72	deleterious	-6,1	low_impact	1,9	neutral	0,89	neutral	0,73	deleterious	3,46	23	0,46	0,65	disease	0,53	disease	0,68	neutral	0,35	disease	0,51	0	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	-0,15	medium_impact	0,53	0,52	0,9	29,2	19,38	N	0,41	N	0,65	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5970	5970	G	A	MI.2020	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	67	23	G	S	Ggc/Agc	-3,81	0	0	benign	0,27	deleterious	0,04	neutral	2,88	neutral	-0,63	deleterious	-2,62	low_impact	1,78	damaging	0,52	damaging	0,28	deleterious	4	23,6	0,31	0,55	neutral	0,2	disease	0,76	neutral	0,35	disease	0,55	1	neutral	0,95	neutral	0,39	neutral	-2	neutral	0,27	medium_impact	-0,35	medium_impact	-0,58	medium_impact	0,55	0,78	0,9	3,31	7,62	N	0,37	N	0,68	disease_causing	0,94	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12783	12783	T	A	MI.20200	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	447	149	I	M	atT/atA	7,3	1	0	probably_damaging	1	neutral	0,24	neutral	4,51	deleterious	-3,18	deleterious	-2,9	low_impact	1,65	neutral	0,74	neutral	0,53	deleterious	3,67	23,3	0,48	0,55	disease	0,78	disease	0,53	disease	0,6	disease	0,57	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	-0,04	medium_impact	0,3	0,82	0,85	10,28	7,1	P	0,55	P	0,76	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12783	12783	T	G	MI.20201	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	447	149	I	M	atT/atG	7,3	1	0	probably_damaging	1	neutral	0,24	neutral	4,51	deleterious	-3,18	deleterious	-2,9	low_impact	1,65	neutral	0,74	neutral	0,53	deleterious	3,34	22,9	0,48	0,55	disease	0,78	disease	0,53	disease	0,6	disease	0,57	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	-0,04	medium_impact	0,3	0,82	0,85	10,28	7,1	P	0,54	P	0,76	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12784	12784	A	C	MI.20202	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	448	150	M	L	Ata/Cta	-3,49	0	0	probably_damaging	0,98	neutral	0,91	neutral	4,74	neutral	0,65	deleterious	-2,96	low_impact	0,94	damaging	0,49	damaging	0,09	deleterious	3,24	22,8	0,49	0,55	neutral	0,43	disease	0,89	disease	0,69	disease	0,56	1	deleterious	0,98	neutral	0,47	neutral	-2	deleterious	0,67	low_impact	-2,35	medium_impact	0,79	medium_impact	-0,34	0,52	0,8	28,03	7,19	N	0,23	N	0,98	disease_causing	0,65	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12784	12784	A	T	MI.20203	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	448	150	M	L	Ata/Tta	-3,49	0	0	probably_damaging	0,98	neutral	0,91	neutral	4,74	neutral	0,65	deleterious	-2,96	low_impact	0,94	damaging	0,49	damaging	0,09	deleterious	3,31	22,9	0,49	0,55	neutral	0,43	disease	0,89	disease	0,69	disease	0,56	1	deleterious	0,98	neutral	0,47	neutral	-2	deleterious	0,67	low_impact	-2,35	medium_impact	0,79	medium_impact	-0,34	0,52	0,8	28,03	7,19	N	0,24	N	0,98	disease_causing	0,65	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12784	12784	A	G	MI.20204	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	448	150	M	V	Ata/Gta	-3,49	0	0	probably_damaging	0,99	neutral	0,6	neutral	4,72	neutral	1	deleterious	-3,95	low_impact	1,54	damaging	0,46	damaging	0,05	deleterious	2,72	20,9	0,58	0,65	disease	0,6	disease	0,9	disease	0,74	disease	0,67	3	deleterious	0,99	neutral	0,31	neutral	-2	deleterious	0,72	low_impact	-2,64	medium_impact	0,33	medium_impact	0,2	0,62	0,8	28,03	7,19	N	0,26	N	0,95	disease_causing	0,7	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12785	12785	T	A	MI.20205	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	449	150	M	K	aTa/aAa	8,44	1	0	probably_damaging	1	neutral	0,3	neutral	4,6	neutral	-2,19	deleterious	-5,92	high_impact	3,87	damaging	0,52	damaging	0,03	deleterious	3,83	23,4	0,24	0,45	disease	0,86	disease	0,94	disease	0,8	disease	0,89	8	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,03	high_impact	2,33	0,61	0,8	28,03	7,19	P	0,62	P	1	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12785	12785	T	C	MI.20206	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	449	150	M	T	aTa/aCa	8,44	1	0	probably_damaging	1	neutral	0,41	neutral	4,67	neutral	0,57	deleterious	-5,92	low_impact	1,39	damaging	0,46	damaging	0,06	deleterious	2,81	21,4	0,53	0,6	neutral	0,48	disease	0,91	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,8	low_impact	-3,6	medium_impact	0,15	medium_impact	0,07	0,48	0,8	28,03	7,19	N	0,44	N	0,99	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12786	12786	A	C	MI.20207	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	450	150	M	I	atA/atC	4,54	1	0	probably_damaging	0,99	neutral	0,56	neutral	4,69	neutral	0,25	deleterious	-3,95	low_impact	1,73	damaging	0,49	damaging	0,06	deleterious	3,39	23	0,5	0,6	disease	0,61	disease	0,94	disease	0,71	disease	0,83	7	deleterious	0,99	neutral	0,29	neutral	-2	deleterious	0,8	low_impact	-2,64	medium_impact	0,29	medium_impact	0,38	0,57	0,8	28,03	7,19	N	0,43	N	0,94	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12786	12786	A	T	MI.20208	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	450	150	M	I	atA/atT	4,54	1	0	probably_damaging	0,99	neutral	0,56	neutral	4,69	neutral	0,25	deleterious	-3,95	low_impact	1,73	damaging	0,49	damaging	0,06	deleterious	3,42	23	0,5	0,6	disease	0,61	disease	0,94	disease	0,71	disease	0,83	7	deleterious	0,99	neutral	0,29	neutral	-2	deleterious	0,8	low_impact	-2,64	medium_impact	0,29	medium_impact	0,38	0,57	0,8	28,03	7,19	N	0,44	N	0,94	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12787	12787	T	C	MI.20209	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	451	151	S	P	Tcc/Ccc	-0,04	0,74	0	probably_damaging	1	neutral	0,2	neutral	4,32	deleterious	-6,35	deleterious	-4,93	high_impact	4,87	damaging	0,36	neutral	0,48	deleterious	3,86	23,5	0,22	0,45	disease	0,96	disease	0,86	disease	0,81	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,1	high_impact	3,25	0,66	0,8	30,35	7,21	P	0,81	P	0,98	disease_causing	0,98	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5970	5970	G	T	MI.2021	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	67	23	G	C	Ggc/Tgc	-3,81	0	0	probably_damaging	0,98	deleterious	0	neutral	2,66	deleterious	-4,15	deleterious	-3,97	high_impact	4,04	damaging	0,55	damaging	0,21	deleterious	4	23,6	0,17	0,55	disease	0,78	disease	0,93	disease	0,59	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,35	low_impact	-1,48	high_impact	2,63	0,64	0,9	3,31	7,62	N	0,33	N	0,7	disease_causing	0,98	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12787	12787	T	A	MI.20210	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	451	151	S	T	Tcc/Acc	-0,04	0,74	0	probably_damaging	1	neutral	0,39	neutral	4,45	deleterious	-3,08	deleterious	-2,96	high_impact	3,71	damaging	0,33	neutral	0,35	deleterious	3,67	23,3	0,31	0,45	disease	0,72	disease	0,74	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,13	high_impact	2,19	0,82	0,85	30,35	7,21	P	0,62	P	0,71	disease_causing	0,88	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12787	12787	T	G	MI.20211	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	451	151	S	A	Tcc/Gcc	-0,04	0,74	0	probably_damaging	1	neutral	0,51	neutral	4,41	deleterious	-3,57	deleterious	-2,96	high_impact	5,21	damaging	0,34	neutral	0,46	deleterious	3,58	23,2	0,32	0,5	disease	0,78	disease	0,76	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,24	high_impact	3,56	0,79	0,85	30,35	7,21	P	0,76	P	0,49	disease_causing	0,69	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12788	12788	C	A	MI.20212	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	452	151	S	Y	tCc/tAc	5,69	1	0	probably_damaging	1	neutral	1	neutral	4,33	deleterious	-5,35	deleterious	-5,92	high_impact	5,21	damaging	0,31	neutral	0,31	deleterious	4,12	23,8	0,19	0,45	disease	0,93	disease	0,91	disease	0,74	disease	0,83	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,86	low_impact	-3,6	high_impact	1,89	high_impact	3,56	0,68	0,85	30,35	7,21	P	0,76	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12788	12788	C	T	MI.20213	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	452	151	S	F	tCc/tTc	5,69	1	0	probably_damaging	1	neutral	0,7	neutral	4,4	deleterious	-4,82	deleterious	-5,92	high_impact	4,87	damaging	0,25	neutral	0,31	deleterious	4,12	23,8	0,19	0,45	disease	0,81	disease	0,91	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,44	high_impact	3,25	0,49	0,8	30,35	7,21	P	0,89	P	0,99	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12788	12788	C	G	MI.20214	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	452	151	S	C	tCc/tGc	5,69	1	0	probably_damaging	1	neutral	0,18	neutral	4,32	deleterious	-6,54	deleterious	-4,93	high_impact	5,21	damaging	0,3	neutral	0,36	deleterious	3,48	23,1	0,24	0,45	disease	0,96	disease	0,85	disease	0,7	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,13	high_impact	3,56	0,65	0,8	30,35	7,21	P	0,78	P	0,99	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12790	12790	T	C	MI.20215	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	454	152	F	L	Ttc/Ctc	-12,43	0	0	probably_damaging	1	neutral	0,77	neutral	4,68	neutral	-1,75	deleterious	-5,91	medium_impact	3,24	damaging	0,49	damaging	0,03	deleterious	4,01	23,6	0,33	0,5	disease	0,62	disease	0,82	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,52	medium_impact	1,76	0,72	0,85	28,86	7,16	N	0,26	N	0,92	polymorphism	0,93	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12790	12790	T	A	MI.20216	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	454	152	F	I	Ttc/Atc	-12,43	0	0	probably_damaging	1	neutral	0,54	neutral	4,51	neutral	-2,63	deleterious	-5,91	high_impact	4,68	damaging	0,49	damaging	0,06	deleterious	4,37	24,1	0,19	0,45	disease	0,75	disease	0,88	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,27	high_impact	3,07	0,61	0,8	28,86	7,16	N	0,52	P	0,95	polymorphism	0,93	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12790	12790	T	G	MI.20217	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	454	152	F	V	Ttc/Gtc	-12,43	0	0	probably_damaging	1	neutral	0,68	neutral	4,5	neutral	-1,77	deleterious	-6,89	high_impact	4,68	damaging	0,46	damaging	0,04	deleterious	4,06	23,7	0,3	0,45	disease	0,59	disease	0,87	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,75	low_impact	-3,6	medium_impact	0,41	high_impact	3,07	0,64	0,8	28,86	7,16	N	0,49	N	0,95	polymorphism	0,87	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12791	12791	T	C	MI.20218	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	455	152	F	S	tTc/tCc	7,3	1	0	probably_damaging	1	neutral	0,53	neutral	4,39	deleterious	-3,2	deleterious	-7,88	high_impact	4,34	damaging	0,51	damaging	0,05	deleterious	4,15	23,8	0,24	0,45	disease	0,84	disease	0,84	disease	0,7	disease	0,78	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,26	high_impact	2,76	0,55	0,8	28,86	7,16	P	0,53	P	0,97	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12791	12791	T	G	MI.20219	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	455	152	F	C	tTc/tGc	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	4,38	deleterious	-4,3	deleterious	-7,86	high_impact	4,68	damaging	0,53	damaging	0,04	deleterious	4,02	23,6	0,26	0,45	disease	0,92	disease	0,88	disease	0,72	disease	0,83	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	-0,13	high_impact	3,07	0,36	0,8	28,86	7,16	P	0,6	P	0,99	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5971	5971	G	T	MI.2022	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	68	23	G	V	gGc/gTc	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,7	neutral	-2,58	deleterious	-3,97	high_impact	4,04	damaging	0,54	damaging	0,24	deleterious	3,61	23,2	0,17	0,55	neutral	0,4	disease	0,9	disease	0,61	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,35	low_impact	-1,48	high_impact	2,63	0,59	0,9	3,31	7,62	N	0,45	N	0,81	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12791	12791	T	A	MI.20220	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	455	152	F	Y	tTc/tAc	7,3	1	0	probably_damaging	1	neutral	1	neutral	4,81	neutral	1,65	deleterious	-2,96	neutral_impact	0,72	damaging	0,48	damaging	0,08	deleterious	4,14	23,8	0,21	0,45	neutral	0,37	disease	0,54	disease	0,65	neutral	0,47	1	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,7	low_impact	-3,6	high_impact	1,89	medium_impact	-0,55	0,59	0,8	28,86	7,16	P	0,53	P	0,88	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12792	12792	C	A	MI.20221	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	456	152	F	L	ttC/ttA	5,69	1	0	probably_damaging	1	neutral	0,77	neutral	4,68	neutral	-1,75	deleterious	-5,91	medium_impact	3,24	damaging	0,49	damaging	0,03	deleterious	4,61	24,4	0,33	0,5	disease	0,62	disease	0,82	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,52	medium_impact	1,76	0,72	0,85	28,86	7,16	N	0,5	N	0,92	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12792	12792	C	G	MI.20222	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	456	152	F	L	ttC/ttG	5,69	1	0	probably_damaging	1	neutral	0,77	neutral	4,68	neutral	-1,75	deleterious	-5,91	medium_impact	3,24	damaging	0,49	damaging	0,03	deleterious	4,31	24	0,33	0,5	disease	0,62	disease	0,82	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,52	medium_impact	1,76	0,72	0,85	28,86	7,16	N	0,5	N	0,92	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12793	12793	T	A	MI.20223	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	457	153	L	M	Ttg/Atg	-3,26	0	0	probably_damaging	1	neutral	0,29	neutral	4,29	deleterious	-4,12	neutral	-1,75	medium_impact	2,52	neutral	0,61	neutral	0,67	deleterious	2,24	17,75	0,26	0,45	disease	0,85	neutral	0,42	neutral	0,4	disease	0,59	2	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,02	medium_impact	1,1	0,65	0,8	12,27	14,39	N	0,37	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12793	12793	T	G	MI.20224	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	457	153	L	V	Ttg/Gtg	-3,26	0	0	probably_damaging	1	neutral	0,57	neutral	4,41	neutral	-2,17	deleterious	-2,87	medium_impact	2,98	damaging	0,5	damaging	0,09	deleterious	3,29	22,8	0,22	0,45	disease	0,78	disease	0,64	disease	0,62	disease	0,67	3	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,3	medium_impact	1,52	0,57	0,8	12,27	14,39	N	0,22	N	0,81	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12794	12794	T	G	MI.20225	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	458	153	L	W	tTg/tGg	-1,42	0	0	probably_damaging	1	neutral	0,19	neutral	4,25	deleterious	-6,85	deleterious	-5,79	high_impact	4,57	damaging	0,6	damaging	0,1	deleterious	3,72	23,3	0,11	0,4	disease	0,98	disease	0,8	disease	0,65	disease	0,83	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,12	high_impact	2,97	0,52	0,8	12,27	14,39	N	0,4	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12794	12794	T	C	MI.20226	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	458	153	L	S	tTg/tCg	-1,42	0	0	probably_damaging	1	neutral	0,51	neutral	4,29	deleterious	-4,83	deleterious	-5,79	high_impact	4,37	damaging	0,56	damaging	0,1	deleterious	3,69	23,3	0,15	0,4	disease	0,92	disease	0,75	disease	0,63	disease	0,8	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,24	high_impact	2,79	0,59	0,8	12,27	14,39	N	0,32	N	0,97	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12795	12795	G	C	MI.20227	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	459	153	L	F	ttG/ttC	4,54	0,64	0	probably_damaging	1	neutral	0,81	neutral	4,34	neutral	-2,19	deleterious	-3,86	medium_impact	2,44	damaging	0,51	damaging	0,08	deleterious	3,38	22,9	0,22	0,45	disease	0,75	disease	0,73	disease	0,61	disease	0,67	3	deleterious	1	neutral	0,41	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,58	medium_impact	1,03	0,55	0,8	12,27	14,39	N	0,28	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12795	12795	G	T	MI.20228	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	459	153	L	F	ttG/ttT	4,54	0,64	0	probably_damaging	1	neutral	0,81	neutral	4,34	neutral	-2,19	deleterious	-3,86	medium_impact	2,44	damaging	0,51	damaging	0,08	deleterious	3,54	23,1	0,22	0,45	disease	0,75	disease	0,73	disease	0,61	disease	0,67	3	deleterious	1	neutral	0,41	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,58	medium_impact	1,03	0,55	0,8	12,27	14,39	N	0,3	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12796	12796	C	G	MI.20229	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	460	154	L	V	Ctc/Gtc	-6,93	0	0	probably_damaging	1	neutral	0,5	neutral	4,02	deleterious	-5,06	deleterious	-2,95	high_impact	5,24	damaging	0,18	neutral	0,32	deleterious	3,39	23	0,22	0,45	disease	0,9	disease	0,7	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,23	high_impact	3,58	0,68	0,85	26,04	7,16	P	0,88	P	0,81	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5971	5971	G	C	MI.2023	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	68	23	G	A	gGc/gCc	7,53	1	0	possibly_damaging	0,44	neutral	0,07	neutral	3,29	neutral	1	deleterious	-2,56	low_impact	1,94	damaging	0,59	neutral	0,4	deleterious	2,97	22,1	0,41	0,55	neutral	0,18	disease	0,54	neutral	0,31	neutral	0,41	2	neutral	0,92	neutral	0,32	neutral	-3	deleterious	0,48	medium_impact	-0,66	medium_impact	-0,43	medium_impact	0,69	0,75	0,9	3,31	7,62	P	0,56	P	0,59	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12796	12796	C	T	MI.20230	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	460	154	L	F	Ctc/Ttc	-6,93	0	0	probably_damaging	1	neutral	0,75	neutral	3,92	deleterious	-6,19	deleterious	-3,94	high_impact	5,24	damaging	0,21	neutral	0,34	deleterious	3,92	23,5	0,18	0,45	disease	0,95	disease	0,78	disease	0,72	disease	0,82	6	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,5	high_impact	3,58	0,58	0,8	26,04	7,16	P	0,86	P	0,99	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12796	12796	C	A	MI.20231	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	460	154	L	I	Ctc/Atc	-6,93	0	0	probably_damaging	1	neutral	0,78	neutral	4,01	deleterious	-4,24	neutral	-1,97	high_impact	4,43	damaging	0,24	neutral	0,49	deleterious	4,05	23,7	0,22	0,45	disease	0,68	disease	0,77	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,54	high_impact	2,84	0,64	0,8	26,04	7,16	P	0,87	P	0,85	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12797	12797	T	G	MI.20232	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	461	154	L	R	cTc/cGc	-0,96	0	0	probably_damaging	1	neutral	0,36	neutral	3,89	deleterious	-7,75	deleterious	-5,91	high_impact	5,24	damaging	0,27	damaging	0,28	deleterious	4,15	23,8	0,09	0,35	disease	0,99	disease	0,89	disease	0,8	disease	0,89	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	0,1	high_impact	3,58	0,39	0,8	26,04	7,16	P	0,86	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12797	12797	T	C	MI.20233	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	461	154	L	P	cTc/cCc	-0,96	0	0	probably_damaging	1	neutral	0,16	neutral	3,95	deleterious	-8,27	deleterious	-6,88	high_impact	5,24	damaging	0,15	neutral	0,36	deleterious	3,84	23,4	0,08	0,35	disease	0,99	disease	0,83	disease	0,8	disease	0,89	8	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,17	high_impact	3,58	0,41	0,8	26,04	7,16	P	0,92	P	0,99	disease_causing	0,78	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12797	12797	T	A	MI.20234	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	461	154	L	H	cTc/cAc	-0,96	0	0	probably_damaging	1	neutral	0,43	neutral	3,89	deleterious	-7,95	deleterious	-6,89	high_impact	5,24	damaging	0,24	neutral	0,29	deleterious	4,09	23,7	0,11	0,4	disease	1	disease	0,82	disease	0,78	disease	0,88	8	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,17	high_impact	3,58	0,42	0,8	26,04	7,16	P	0,85	P	0,97	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12799	12799	A	G	MI.20235	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	463	155	I	V	Atc/Gtc	-8,76	0	0	probably_damaging	1	neutral	0,25	neutral	4,35	neutral	-1,45	neutral	-0,98	medium_impact	2,35	damaging	0,41	damaging	0,1	deleterious	3,03	22,3	0,4	0,5	disease	0,51	neutral	0,47	disease	0,63	neutral	0,46	1	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,65	low_impact	-3,6	medium_impact	-0,03	medium_impact	0,94	0,57	0,8	26,7	7,23	N	0,48	N	0,74	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12799	12799	A	T	MI.20236	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	463	155	I	F	Atc/Ttc	-8,76	0	0	probably_damaging	1	neutral	0,61	neutral	4,17	deleterious	-5,58	deleterious	-3,92	high_impact	5,04	damaging	0,35	damaging	0,07	deleterious	3,74	23,3	0,17	0,45	disease	0,91	disease	0,82	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,34	high_impact	3,4	0,56	0,8	26,7	7,23	P	0,62	P	0,96	polymorphism	0,7	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12799	12799	A	C	MI.20237	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	463	155	I	L	Atc/Ctc	-8,76	0	0	probably_damaging	1	neutral	1	neutral	4,29	deleterious	-3,11	neutral	-1,96	high_impact	4,14	damaging	0,36	damaging	0,1	deleterious	3,74	23,3	0,23	0,45	neutral	0,47	disease	0,69	disease	0,62	disease	0,66	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,69	low_impact	-3,6	high_impact	1,89	high_impact	2,58	0,56	0,8	26,7	7,23	N	0,47	N	0,86	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12800	12800	T	A	MI.20238	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	464	155	I	N	aTc/aAc	8,44	1	0	probably_damaging	1	neutral	0,21	neutral	4,18	deleterious	-6,74	deleterious	-6,86	high_impact	5,04	damaging	0,34	damaging	0,1	deleterious	4,38	24,1	0,12	0,4	disease	0,96	disease	0,86	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,09	high_impact	3,4	0,45	0,8	26,7	7,23	P	0,72	P	0,99	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12800	12800	T	G	MI.20239	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	464	155	I	S	aTc/aGc	8,44	1	0	probably_damaging	1	neutral	0,55	neutral	4,19	deleterious	-4,94	deleterious	-5,88	high_impact	5,04	damaging	0,43	damaging	0,12	deleterious	4,24	23,9	0,14	0,4	disease	0,62	disease	0,84	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,28	high_impact	3,4	0,43	0,8	26,7	7,23	P	0,74	P	0,96	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5971	5971	G	A	MI.2024	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	68	23	G	D	gGc/gAc	7,53	1	0	possibly_damaging	0,88	deleterious	0	neutral	2,65	deleterious	-5,36	deleterious	-3,13	high_impact	4,73	damaging	0,49	damaging	0,26	deleterious	3,63	23,2	0,13	0,55	disease	0,53	disease	0,92	disease	0,7	disease	0,8	6	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,81	low_impact	-1,57	low_impact	-1,48	high_impact	3,27	0,48	0,9	3,31	7,62	P	0,67	P	0,21	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12800	12800	T	C	MI.20240	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	464	155	I	T	aTc/aCc	8,44	1	0	probably_damaging	1	neutral	0,21	neutral	4,24	deleterious	-4,51	deleterious	-4,9	high_impact	5,04	damaging	0,39	damaging	0,09	deleterious	3,38	22,9	0,26	0,45	disease	0,86	disease	0,72	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	-0,09	high_impact	3,4	0,48	0,8	26,7	7,23	P	0,76	P	0,96	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12801	12801	C	G	MI.20241	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	465	155	I	M	atC/atG	5,69	1	0	probably_damaging	1	neutral	0,5	neutral	4,19	deleterious	-5,11	deleterious	-2,92	high_impact	5,04	damaging	0,45	damaging	0,14	deleterious	3,29	22,8	0,28	0,45	disease	0,91	disease	0,66	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,23	high_impact	3,4	0,59	0,8	26,7	7,23	P	0,73	P	0,76	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12801	12801	C	A	MI.20242	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	465	155	I	M	atC/atA	5,69	1	0	probably_damaging	1	neutral	0,5	neutral	4,19	deleterious	-5,11	deleterious	-2,92	high_impact	5,04	damaging	0,45	damaging	0,14	deleterious	3,72	23,3	0,28	0,45	disease	0,91	disease	0,66	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,23	high_impact	3,4	0,59	0,8	26,7	7,23	P	0,74	P	0,76	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12802	12802	A	G	MI.20243	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	466	156	S	G	Agt/Ggt	-4,17	0	0	benign	0,03	neutral	0,43	neutral	4,7	neutral	2,51	neutral	4,43	neutral_impact	-1,15	neutral	0,82	neutral	0,98	neutral	-1,14	0,01	0,53	0,6	neutral	0,46	neutral	0,11	neutral	0,32	neutral	0,25	5	neutral	0,55	deleterious	0,7	neutral	-6	neutral	0,13	medium_impact	0,69	medium_impact	0,17	low_impact	-2,25	0,78	0,85	7,79	11,3	N	0,36	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12802	12802	A	T	MI.20244	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	466	156	S	C	Agt/Tgt	-4,17	0	0	probably_damaging	0,98	neutral	0,17	neutral	4,46	deleterious	-3,24	deleterious	-3,25	medium_impact	3,43	damaging	0,59	neutral	0,39	deleterious	3,23	22,8	0,29	0,45	disease	0,91	disease	0,87	disease	0,59	disease	0,85	7	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,83	low_impact	-2,35	medium_impact	-0,15	medium_impact	1,93	0,8	0,85	7,79	11,3	N	0,33	N	0,73	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12802	12802	A	C	MI.20245	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	466	156	S	R	Agt/Cgt	-4,17	0	0	probably_damaging	0,93	neutral	0,33	neutral	4,48	neutral	-2,2	neutral	-2,37	medium_impact	3,43	neutral	0,66	neutral	0,54	deleterious	3,48	23,1	0,25	0,45	disease	0,8	disease	0,94	disease	0,72	disease	0,87	7	neutral	0,94	neutral	0,2	deleterious	1	deleterious	0,73	low_impact	-1,81	medium_impact	0,06	medium_impact	1,93	0,87	0,9	7,79	11,3	N	0,33	N	0,67	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12803	12803	G	A	MI.20246	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	467	156	S	N	aGt/aAt	1,1	0,86	0	possibly_damaging	0,72	neutral	0,3	neutral	4,5	neutral	-1,47	neutral	-0,43	neutral_impact	0,47	neutral	0,73	neutral	0,8	neutral	1,79	14,95	0,69	0,75	disease	0,74	disease	0,78	disease	0,55	disease	0,59	2	neutral	0,78	neutral	0,29	neutral	-3	deleterious	0,47	low_impact	-1,14	medium_impact	0,03	medium_impact	-0,77	0,71	0,85	7,79	11,3	N	0,32	N	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12803	12803	G	T	MI.20247	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	467	156	S	I	aGt/aTt	1,1	0,86	0	probably_damaging	0,95	neutral	0,49	neutral	4,53	neutral	-0,42	deleterious	-4,23	medium_impact	2,54	neutral	0,6	neutral	0,57	deleterious	3,96	23,6	0,43	0,55	disease	0,62	disease	0,93	disease	0,61	disease	0,79	6	neutral	0,94	neutral	0,27	deleterious	1	deleterious	0,78	low_impact	-1,96	medium_impact	0,22	medium_impact	1,12	0,85	0,9	7,79	11,3	N	0,28	N	0,85	polymorphism	0,97	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12803	12803	G	C	MI.20248	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	467	156	S	T	aGt/aCt	1,1	0,86	0	possibly_damaging	0,78	neutral	0,43	neutral	4,53	neutral	-0,78	neutral	-2,11	medium_impact	3,43	neutral	0,61	neutral	0,63	deleterious	1,86	15,33	0,56	0,6	disease	0,71	disease	0,65	disease	0,6	disease	0,71	4	neutral	0,78	neutral	0,33	NA	0	deleterious	0,5	low_impact	-1,27	medium_impact	0,17	medium_impact	1,93	0,83	0,9	7,79	11,3	N	0,35	N	0,51	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12805	12805	T	G	MI.20249	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	469	157	W	G	Tga/Gga	-6,01	0	0	probably_damaging	1	neutral	0,47	neutral	4,66	neutral	-1	deleterious	-12,83	medium_impact	2,56	damaging	0,55	damaging	0,04	deleterious	3,85	23,4	0,36	0,5	disease	0,82	disease	0,91	disease	0,81	disease	0,85	7	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,2	medium_impact	1,14	0,37	0,8	29,19	7,25	N	0,32	N	0,97	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5973	5973	G	T	MI.2025	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	70	24	A	S	Gca/Tca	-11,44	0	0	benign	0,18	neutral	0,13	neutral	2,76	neutral	-0,84	neutral	-0,77	low_impact	1,64	damaging	0,58	neutral	0,66	deleterious	0,65	8,5	0,46	0,55	neutral	0,39	disease	0,56	neutral	0,2	neutral	0,46	1	neutral	0,85	deleterious	0,48	neutral	-6	neutral	0,23	medium_impact	-0,14	medium_impact	-0,27	medium_impact	0,42	0,77	0,9	3,12	8,36	P	0,57	P	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12805	12805	T	C	MI.20250	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	469	157	W	R	Tga/Cga	-6,01	0	0	probably_damaging	1	neutral	0,43	neutral	4,66	neutral	-0,88	deleterious	-13,81	medium_impact	2,42	damaging	0,57	damaging	0,04	deleterious	3,52	23,1	0,54	0,6	disease	0,83	disease	0,94	disease	0,85	disease	0,89	8	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,88	low_impact	-3,6	medium_impact	0,17	medium_impact	1,01	0,36	0,8	29,19	7,25	N	0,32	N	0,97	disease_causing	0,97	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12806	12806	G	T	MI.20251	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	470	157	W	L	tGa/tTa	5,69	1	0	probably_damaging	1	neutral	0,95	neutral	4,78	neutral	1,51	deleterious	-12,83	medium_impact	2,38	damaging	0,53	damaging	0,02	deleterious	4,21	23,9	0,45	0,55	neutral	0,42	disease	0,91	disease	0,8	disease	0,81	6	deleterious	1	deleterious	0,48	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,94	medium_impact	0,97	0,35	0,8	29,19	7,25	N	0,47	N	0,97	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12806	12806	G	C	MI.20252	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	470	157	W	S	tGa/tCa	5,69	1	0	probably_damaging	1	neutral	0,47	neutral	4,67	neutral	-0,44	deleterious	-13,81	high_impact	3,65	damaging	0,52	damaging	0,04	deleterious	3,97	23,6	0,37	0,5	disease	0,71	disease	0,93	disease	0,8	disease	0,86	7	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,2	high_impact	2,13	0,31	0,8	29,19	7,25	N	0,52	P	0,95	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12807	12807	A	C	MI.20253	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	471	157	W	C	tgA/tgC	9,13	1	0	probably_damaging	1	neutral	0,17	neutral	4,64	neutral	-2,48	deleterious	-12,83	medium_impact	3,19	damaging	0,51	damaging	0,03	deleterious	4,08	23,7	0,35	0,5	disease	0,89	disease	0,93	disease	0,83	disease	0,89	8	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	-0,15	medium_impact	1,71	0,33	0,8	29,19	7,25	P	0,52	P	0,98	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12807	12807	A	T	MI.20254	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	471	157	W	C	tgA/tgT	9,13	1	0	probably_damaging	1	neutral	0,17	neutral	4,64	neutral	-2,48	deleterious	-12,83	medium_impact	3,19	damaging	0,51	damaging	0,03	deleterious	4,05	23,7	0,35	0,5	disease	0,89	disease	0,93	disease	0,83	disease	0,89	8	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	-0,15	medium_impact	1,71	0,33	0,8	29,19	7,25	P	0,52	P	0,98	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12808	12808	T	G	MI.20255	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	472	158	W	G	Tga/Gga	1,56	1	0	probably_damaging	1	neutral	0,37	neutral	4,48	neutral	-2,56	deleterious	-12,8	high_impact	3,71	damaging	0,52	damaging	0,04	deleterious	3,85	23,4	0,31	0,45	disease	0,77	disease	0,9	disease	0,85	disease	0,85	7	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,11	high_impact	2,19	0,28	0,8	26,87	7,26	N	0,47	N	0,97	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12808	12808	T	C	MI.20256	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	472	158	W	R	Tga/Cga	1,56	1	0	probably_damaging	1	neutral	0,37	neutral	4,46	neutral	-2,72	deleterious	-13,79	high_impact	3,6	damaging	0,54	damaging	0,03	deleterious	3,53	23,1	0,4	0,5	disease	0,78	disease	0,94	disease	0,87	disease	0,88	8	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,11	high_impact	2,09	0,26	0,8	26,87	7,26	N	0,44	N	0,97	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12809	12809	G	T	MI.20257	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	473	158	W	L	tGa/tTa	7,3	1	0	probably_damaging	1	neutral	0,75	neutral	4,51	deleterious	-3,38	deleterious	-12,8	high_impact	4,05	damaging	0,51	damaging	0,03	deleterious	4,22	23,9	0,25	0,45	disease	0,77	disease	0,9	disease	0,83	disease	0,84	7	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,5	high_impact	2,5	0,24	0,8	26,87	7,26	P	0,57	P	0,97	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12809	12809	G	C	MI.20258	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	473	158	W	S	tGa/tCa	7,3	1	0	probably_damaging	1	neutral	0,48	neutral	4,46	neutral	-2,89	deleterious	-13,79	medium_impact	3,18	damaging	0,53	damaging	0,04	deleterious	3,98	23,6	0,27	0,45	disease	0,65	disease	0,93	disease	0,83	disease	0,85	7	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,21	medium_impact	1,7	0,24	0,8	26,87	7,26	N	0,48	N	0,95	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12810	12810	A	T	MI.20259	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	474	158	W	C	tgA/tgT	7,3	1	0,02	probably_damaging	1	neutral	0,18	neutral	4,43	deleterious	-6,77	deleterious	-12,8	high_impact	4,75	damaging	0,51	damaging	0,03	deleterious	4,06	23,7	0,3	0,45	disease	0,97	disease	0,92	disease	0,86	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,13	high_impact	3,14	0,2	0,8	26,87	7,26	P	0,54	P	0,98	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5973	5973	G	C	MI.2026	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	70	24	A	P	Gca/Cca	-11,44	0	0	possibly_damaging	0,53	neutral	0,05	neutral	2,73	neutral	-1,87	neutral	-1,53	medium_impact	3,31	damaging	0,53	neutral	0,43	deleterious	3,36	22,9	0,15	0,55	disease	0,63	disease	0,89	disease	0,58	disease	0,79	6	neutral	0,95	neutral	0,26	NA	0	deleterious	0,71	medium_impact	-0,81	medium_impact	-0,52	medium_impact	1,96	0,81	0,9	3,12	8,36	N	0,4	N	0,85	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12810	12810	A	C	MI.20260	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	474	158	W	C	tgA/tgC	7,3	1	0,02	probably_damaging	1	neutral	0,18	neutral	4,43	deleterious	-6,77	deleterious	-12,8	high_impact	4,75	damaging	0,51	damaging	0,03	deleterious	3,99	23,6	0,3	0,45	disease	0,97	disease	0,92	disease	0,86	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,13	high_impact	3,14	0,2	0,8	26,87	7,26	P	0,54	P	0,98	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12811	12811	T	G	MI.20261	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	475	159	Y	D	Tac/Gac	-0,27	0	0,1	possibly_damaging	0,75	neutral	0,22	neutral	4,66	neutral	-2,49	deleterious	-7,26	medium_impact	3,46	neutral	0,75	neutral	0,37	deleterious	3,54	23,1	0,41	0,5	disease	0,73	disease	0,91	disease	0,63	disease	0,75	5	neutral	0,85	neutral	0,24	NA	0	deleterious	0,56	low_impact	-1,2	medium_impact	-0,07	medium_impact	1,96	0,37	0,8	6,97	11,79	N	0,36	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12811	12811	T	A	MI.20262	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	475	159	Y	N	Tac/Aac	-0,27	0	0,1	possibly_damaging	0,48	neutral	0,31	neutral	4,7	neutral	-2,14	deleterious	-6,07	low_impact	1,84	neutral	0,79	neutral	0,69	deleterious	2,25	17,87	0,46	0,55	disease	0,65	disease	0,88	disease	0,58	disease	0,68	4	neutral	0,66	neutral	0,42	neutral	-3	deleterious	0,43	medium_impact	-0,71	medium_impact	0,04	medium_impact	0,48	0,35	0,8	6,97	11,79	N	0,28	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12811	12811	T	C	MI.20263	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	475	159	Y	H	Tac/Cac	-0,27	0	0,1	benign	0,01	neutral	0,52	neutral	4,62	neutral	-1,53	neutral	-1,81	low_impact	0,92	neutral	0,83	neutral	0,97	deleterious	0,04	3,02	0,62	0,65	neutral	0,41	neutral	0,43	neutral	0,33	neutral	0,45	1	neutral	0,46	deleterious	0,76	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,25	medium_impact	-0,36	0,4	0,8	6,97	11,79	N	0,32	N	0,98	disease_causing_automatic	0	0,03	rs199974018	Pathogenic	Leber's_optic_atrophy	RCV000055698.1	MedGen:OMIM:SNOMED_CT	.	.	.	.	T12811C	Possible LHON factor	+	-	Reported	4
chrM	12812	12812	A	T	MI.20264	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	476	159	Y	F	tAc/tTc	-0,96	0	0	possibly_damaging	0,64	neutral	0,81	neutral	4,65	neutral	-0,99	deleterious	-2,92	neutral_impact	0,32	neutral	0,82	neutral	0,98	deleterious	0,41	6,7	0,4	0,5	disease	0,55	disease	0,66	neutral	0,35	neutral	0,49	0	neutral	0,57	deleterious	0,59	neutral	-3	deleterious	0,53	medium_impact	-0,98	medium_impact	0,58	medium_impact	-0,91	0,32	0,8	6,97	11,79	N	0,23	N	0,8	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12812	12812	A	G	MI.20265	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	476	159	Y	C	tAc/tGc	-0,96	0	0	benign	0,06	neutral	0,17	neutral	4,61	deleterious	-6,08	deleterious	-6,93	medium_impact	2,96	neutral	0,76	neutral	0,43	neutral	1,46	13,1	0,32	0,5	disease	0,95	disease	0,91	disease	0,55	disease	0,83	7	neutral	0,82	deleterious	0,56	neutral	-3	neutral	0,3	medium_impact	0,39	medium_impact	-0,15	medium_impact	1,5	0,13	0,8	6,97	11,79	N	0,33	N	1	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12812	12812	A	C	MI.20266	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	476	159	Y	S	tAc/tCc	-0,96	0	0	possibly_damaging	0,56	neutral	0,5	neutral	4,72	neutral	-1,86	deleterious	-6,43	low_impact	1,16	neutral	0,85	neutral	0,8	deleterious	1,82	15,11	0,32	0,5	disease	0,53	disease	0,78	neutral	0,44	disease	0,53	1	neutral	0,55	deleterious	0,47	neutral	-3	deleterious	0,44	medium_impact	-0,85	medium_impact	0,23	medium_impact	-0,14	0,41	0,8	6,97	11,79	N	0,27	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12814	12814	G	C	MI.20267	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	478	160	A	P	Gcc/Ccc	-9,68	0	0	probably_damaging	0,95	neutral	0,2	neutral	4,59	neutral	-1,98	neutral	-2,15	low_impact	1,81	neutral	0,64	neutral	0,35	deleterious	3,81	23,4	0,33	0,5	disease	0,82	disease	0,93	disease	0,57	disease	0,8	6	neutral	0,97	neutral	0,13	neutral	-2	deleterious	0,88	low_impact	-1,96	medium_impact	-0,1	medium_impact	0,45	0,77	0,85	17,08	18,65	N	0,25	N	0,86	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12814	12814	G	A	MI.20268	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	478	160	A	T	Gcc/Acc	-9,68	0	0	possibly_damaging	0,73	neutral	0,39	neutral	4,68	neutral	0,79	neutral	-1,89	neutral_impact	-0,45	neutral	0,72	neutral	0,8	deleterious	4,28	24	0,58	0,65	neutral	0,4	neutral	0,45	neutral	0,49	neutral	0,48	0	neutral	0,74	neutral	0,33	neutral	-3	deleterious	0,69	low_impact	-1,16	medium_impact	0,13	low_impact	-1,61	0,72	0,85	17,08	18,65	N	0,33	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12814	12814	G	T	MI.20269	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	478	160	A	S	Gcc/Tcc	-9,68	0	0	benign	0,18	neutral	0,41	neutral	4,66	neutral	0,35	neutral	0,13	neutral_impact	-0,03	neutral	0,83	neutral	0,88	deleterious	2,53	19,64	0,55	0,6	neutral	0,45	disease	0,54	neutral	0,31	neutral	0,47	1	neutral	0,51	deleterious	0,62	neutral	-6	deleterious	0,73	medium_impact	-0,12	medium_impact	0,15	low_impact	-1,23	0,75	0,85	17,08	18,65	N	0,34	N	0,61	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5973	5973	G	A	MI.2027	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	70	24	A	T	Gca/Aca	-11,44	0	0	benign	0,01	neutral	0,16	neutral	2,79	neutral	-0,28	neutral	-0,74	low_impact	1,54	neutral	0,6	neutral	0,8	neutral	0,89	10,02	0,44	0,55	neutral	0,33	neutral	0,48	neutral	0,22	neutral	0,46	1	neutral	0,84	deleterious	0,58	neutral	-6	neutral	0,16	medium_impact	1,12	medium_impact	-0,21	medium_impact	0,32	0,66	0,9	3,12	8,36	P	0,58	P	0,2	polymorphism	1	0,02	.	.	.	.	.	pancreatic cancer cell line	.	.	0,59	G5973A	Prostate Cancer	+	-	Reported	1
chrM	12815	12815	C	T	MI.20270	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	479	160	A	V	gCc/gTc	2,25	0,6	0	possibly_damaging	0,9	neutral	0,5	neutral	4,61	neutral	-1,98	deleterious	-3,02	medium_impact	2,16	neutral	0,9	neutral	0,69	deleterious	4,47	24,2	0,58	0,65	disease	0,79	disease	0,74	disease	0,55	disease	0,73	5	neutral	0,89	neutral	0,3	NA	0	deleterious	0,78	low_impact	-1,65	medium_impact	0,23	medium_impact	0,77	0,6	0,8	17,08	18,65	N	0,36	N	0,74	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12815	12815	C	G	MI.20271	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	479	160	A	G	gCc/gGc	2,25	0,6	0	benign	0,04	neutral	0,37	neutral	4,64	neutral	1,26	neutral	4,61	neutral_impact	-0,35	neutral	0,73	neutral	0,95	neutral	1,26	12,06	0,6	0,65	neutral	0,36	neutral	0,12	neutral	0,24	neutral	0,28	4	neutral	0,6	deleterious	0,67	neutral	-6	deleterious	0,67	medium_impact	0,57	medium_impact	0,11	low_impact	-1,52	0,8	0,85	17,08	18,65	N	0,39	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12815	12815	C	A	MI.20272	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	479	160	A	D	gCc/gAc	2,25	0,6	0	possibly_damaging	0,87	neutral	0,21	neutral	4,64	neutral	0,21	neutral	-1,28	low_impact	1,1	neutral	0,69	neutral	0,43	deleterious	4,48	24,2	0,44	0,55	disease	0,52	disease	0,9	disease	0,64	disease	0,81	6	neutral	0,92	neutral	0,17	neutral	-3	deleterious	0,82	low_impact	-1,53	medium_impact	-0,09	medium_impact	-0,2	0,61	0,8	17,08	18,65	N	0,31	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12817	12817	C	T	MI.20273	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	481	161	R	W	Cga/Tga	-7,61	0	0	probably_damaging	1	neutral	0,22	neutral	4,52	deleterious	-6,71	deleterious	-7,89	high_impact	4,63	damaging	0,43	damaging	0,01	deleterious	5,21	25,5	0,42	0,55	disease	0,83	disease	0,91	disease	0,77	disease	0,8	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,07	high_impact	3,03	0,88	0,9	26,53	7,17	N	0,49	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12817	12817	C	G	MI.20274	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	481	161	R	G	Cga/Gga	-7,61	0	0	probably_damaging	1	neutral	0,38	neutral	4,54	neutral	-2,6	deleterious	-6,91	high_impact	3,54	damaging	0,42	damaging	0,03	deleterious	4,23	23,9	0,35	0,5	disease	0,75	disease	0,83	disease	0,77	disease	0,77	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,12	high_impact	2,03	0,49	0,8	26,53	7,17	N	0,41	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12818	12818	G	T	MI.20275	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	482	161	R	L	cGa/cTa	2,25	0,96	0	probably_damaging	1	neutral	0,68	neutral	4,55	deleterious	-4,04	deleterious	-6,91	high_impact	3,54	damaging	0,41	damaging	0,01	deleterious	4,35	24,1	0,34	0,5	disease	0,59	disease	0,93	disease	0,75	disease	0,83	6	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,41	high_impact	2,03	0,41	0,8	26,53	7,17	P	0,58	P	1	disease_causing	0,97	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12818	12818	G	C	MI.20276	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	482	161	R	P	cGa/cCa	2,25	0,96	0	probably_damaging	1	neutral	0,21	neutral	4,53	deleterious	-3,37	deleterious	-6,91	high_impact	4,29	damaging	0,36	damaging	0,02	deleterious	4,24	23,9	0,29	0,45	disease	0,79	disease	0,9	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,09	high_impact	2,72	0,4	0,8	26,53	7,17	P	0,68	P	0,99	disease_causing	0,97	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12818	12818	G	A	MI.20277	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	482	161	R	Q	cGa/cAa	2,25	0,96	0	probably_damaging	1	neutral	0,3	neutral	4,65	neutral	-2,29	deleterious	-3,95	medium_impact	2,9	damaging	0,44	damaging	0,02	deleterious	4,51	24,3	0,5	0,6	disease	0,65	disease	0,83	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,03	medium_impact	1,45	0,89	0,9	26,53	7,17	P	0,55	P	0,99	disease_causing	0,8	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12820	12820	G	T	MI.20278	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	484	162	A	S	Gca/Tca	-1,65	0	0,01	benign	0,02	neutral	0,44	neutral	4,67	neutral	-1,07	neutral	0,46	neutral_impact	-0,14	neutral	0,81	neutral	0,93	deleterious	0,43	6,89	0,66	0,7	disease	0,65	neutral	0,5	neutral	0,18	neutral	0,48	0	neutral	0,54	deleterious	0,71	neutral	-6	neutral	0,22	medium_impact	0,86	medium_impact	0,18	low_impact	-1,33	0,94	0,95	4,64	9,64	N	0,4	N	0,51	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12820	12820	G	A	MI.20279	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	484	162	A	T	Gca/Aca	-1,65	0	0,01	benign	0	neutral	0,41	neutral	4,61	neutral	-1,57	neutral	2,21	neutral_impact	0,43	neutral	0,88	neutral	0,95	neutral	-0,38	0,44	0,61	0,65	disease	0,59	neutral	0,25	neutral	0,16	disease	0,55	1	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,16	high_impact	2,1	medium_impact	0,15	medium_impact	-0,81	0,83	0,85	4,64	9,64	N	0,48	N	0,03	polymorphism	1	0,01	rs200567053	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5974	5974	C	G	MI.2028	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	71	24	A	G	gCa/gGa	3,6	1	0	benign	0,07	neutral	0,1	neutral	2,73	neutral	-2,12	neutral	-1,53	medium_impact	2,03	damaging	0,59	neutral	0,6	deleterious	1,82	15,09	0,27	0,55	neutral	0,4	disease	0,58	neutral	0,31	neutral	0,49	0	neutral	0,89	deleterious	0,52	neutral	-3	neutral	0,2	medium_impact	0,3	medium_impact	-0,34	medium_impact	0,78	0,68	0,9	3,12	8,36	P	0,58	P	0,56	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12820	12820	G	C	MI.20280	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	484	162	A	P	Gca/Cca	-1,65	0	0,01	benign	0,1	neutral	0,2	neutral	4,69	neutral	-0,1	neutral	-1,56	neutral_impact	0,34	neutral	0,77	neutral	0,57	deleterious	1,92	15,71	0,42	0,55	disease	0,52	disease	0,84	neutral	0,37	disease	0,54	1	neutral	0,78	deleterious	0,55	neutral	-6	neutral	0,3	medium_impact	0,16	medium_impact	-0,1	medium_impact	-0,89	0,91	0,95	4,64	9,64	N	0,29	N	0,66	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12821	12821	C	T	MI.20281	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	485	162	A	V	gCa/gTa	-2,34	0	0	benign	0,03	neutral	0,5	neutral	4,61	neutral	-2,12	neutral	-1,25	low_impact	1,24	neutral	0,76	neutral	0,58	deleterious	2,49	19,4	0,57	0,65	disease	0,82	disease	0,65	neutral	0,46	disease	0,6	2	neutral	0,46	deleterious	0,74	neutral	-6	neutral	0,26	medium_impact	0,69	medium_impact	0,23	medium_impact	-0,07	0,74	0,85	4,64	9,64	N	0,23	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12821	12821	C	G	MI.20282	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	485	162	A	G	gCa/gGa	-2,34	0	0	benign	0,05	neutral	0,39	neutral	4,57	neutral	-1,34	neutral	-2,16	low_impact	1,75	neutral	0,73	neutral	0,56	deleterious	2,01	16,26	0,61	0,65	disease	0,81	disease	0,7	neutral	0,44	disease	0,59	2	neutral	0,58	deleterious	0,67	neutral	-6	neutral	0,27	medium_impact	0,47	medium_impact	0,13	medium_impact	0,4	0,93	0,95	4,64	9,64	N	0,26	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12821	12821	C	A	MI.20283	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	485	162	A	E	gCa/gAa	-2,34	0	0	benign	0	neutral	0,28	neutral	4,68	neutral	-0,48	neutral	-1,68	neutral_impact	0,57	neutral	0,76	neutral	0,5	deleterious	2,51	19,56	0,49	0,55	neutral	0,49	disease	0,82	disease	0,51	disease	0,54	1	neutral	0,72	deleterious	0,64	neutral	-6	neutral	0,25	high_impact	2,1	medium_impact	0,01	medium_impact	-0,68	0,8	0,85	4,64	9,64	N	0,31	N	0,64	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12823	12823	G	C	MI.20284	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	487	163	D	H	Gat/Cat	-0,04	0,57	0	probably_damaging	0,99	neutral	0,54	neutral	4,57	neutral	-2,8	deleterious	-6,5	medium_impact	3,11	neutral	0,71	damaging	0,24	deleterious	3,68	23,3	0,6	0,65	disease	0,81	disease	0,79	disease	0,68	disease	0,73	5	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,78	low_impact	-2,64	medium_impact	0,27	medium_impact	1,64	0,44	0,8	4,98	7,98	N	0,24	N	0,99	disease_causing	0,72	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12823	12823	G	A	MI.20285	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	487	163	D	N	Gat/Aat	-0,04	0,57	0	probably_damaging	0,94	neutral	0,34	neutral	4,64	neutral	-0,64	deleterious	-4,66	neutral_impact	0,78	neutral	0,76	neutral	0,54	deleterious	3,98	23,6	0,75	0,8	disease	0,54	disease	0,74	neutral	0,38	disease	0,52	0	neutral	0,94	neutral	0,2	neutral	-2	deleterious	0,68	low_impact	-1,88	medium_impact	0,07	medium_impact	-0,49	0,76	0,85	4,98	7,98	N	0,23	N	0,98	polymorphism	0,67	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12823	12823	G	T	MI.20286	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	487	163	D	Y	Gat/Tat	-0,04	0,57	0	probably_damaging	0,99	neutral	1	neutral	4,56	deleterious	-3,59	deleterious	-8,48	medium_impact	2,62	neutral	0,69	neutral	0,51	deleterious	3,93	23,5	0,45	0,55	disease	0,88	disease	0,92	disease	0,68	disease	0,8	6	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,83	low_impact	-2,64	high_impact	1,89	medium_impact	1,19	0,2	0,8	4,98	7,98	N	0,27	N	0,99	disease_causing	0,84	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12824	12824	A	T	MI.20287	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	488	163	D	V	gAt/gTt	4,31	1	0	probably_damaging	0,98	neutral	0,52	neutral	4,57	neutral	-2,38	deleterious	-8,48	medium_impact	2,31	neutral	0,69	neutral	0,33	deleterious	3,65	23,2	0,33	0,5	neutral	0,41	disease	0,88	disease	0,63	disease	0,73	5	neutral	0,98	neutral	0,27	deleterious	1	deleterious	0,72	low_impact	-2,35	medium_impact	0,25	medium_impact	0,91	0,23	0,8	4,98	7,98	N	0,39	N	0,99	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12824	12824	A	G	MI.20288	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	488	163	D	G	gAt/gGt	4,31	1	0	probably_damaging	0,95	neutral	0,35	neutral	4,57	neutral	-1,61	deleterious	-6,65	medium_impact	2,12	neutral	0,71	neutral	0,45	deleterious	3,75	23,3	0,44	0,55	disease	0,68	disease	0,86	disease	0,65	disease	0,71	4	neutral	0,96	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-1,96	medium_impact	0,08	medium_impact	0,73	0,4	0,8	4,98	7,98	N	0,42	N	0,98	disease_causing	0,83	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12824	12824	A	C	MI.20289	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	488	163	D	A	gAt/gCt	4,31	1	0	probably_damaging	0,91	neutral	0,55	neutral	4,63	neutral	-0,38	deleterious	-7,5	low_impact	1,15	neutral	0,73	neutral	0,42	deleterious	3,4	23	0,32	0,5	neutral	0,46	disease	0,76	disease	0,63	disease	0,63	3	neutral	0,9	neutral	0,32	neutral	-2	deleterious	0,65	low_impact	-1,7	medium_impact	0,28	medium_impact	-0,15	0,43	0,8	4,98	7,98	N	0,33	N	0,94	disease_causing	0,78	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5974	5974	C	A	MI.2029	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	71	24	A	E	gCa/gAa	3,6	1	0	possibly_damaging	0,56	neutral	0,07	neutral	2,72	neutral	-2,63	neutral	-1,5	medium_impact	3,31	damaging	0,58	neutral	0,48	deleterious	3,94	23,5	0,2	0,55	neutral	0,2	disease	0,85	neutral	0,49	disease	0,76	5	neutral	0,93	neutral	0,26	NA	0	deleterious	0,49	medium_impact	-0,86	medium_impact	-0,43	medium_impact	1,96	0,72	0,9	3,12	8,36	P	0,56	P	0,76	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12825	12825	T	A	MI.20290	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	489	163	D	E	gaT/gaA	8,44	1	0	benign	0,15	neutral	0,33	neutral	4,74	neutral	0,37	deleterious	-3,42	neutral_impact	0,28	neutral	0,84	neutral	0,77	deleterious	2,08	16,7	0,52	0,6	neutral	0,39	disease	0,57	neutral	0,34	neutral	0,45	1	neutral	0,61	deleterious	0,59	neutral	-6	neutral	0,2	medium_impact	-0,03	medium_impact	0,06	medium_impact	-0,95	0,51	0,8	4,98	7,98	N	0,51	P	0,91	polymorphism	0,71	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12825	12825	T	G	MI.20291	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	489	163	D	E	gaT/gaG	8,44	1	0	benign	0,15	neutral	0,33	neutral	4,74	neutral	0,37	deleterious	-3,42	neutral_impact	0,28	neutral	0,84	neutral	0,77	deleterious	1,94	15,85	0,52	0,6	neutral	0,39	disease	0,57	neutral	0,34	neutral	0,45	1	neutral	0,61	deleterious	0,59	neutral	-6	neutral	0,2	medium_impact	-0,03	medium_impact	0,06	medium_impact	-0,95	0,51	0,8	4,98	7,98	N	0,51	P	0,91	polymorphism	0,71	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12826	12826	G	T	MI.20292	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	490	164	A	S	Gcc/Tcc	-5,32	0	0	probably_damaging	1	neutral	0,41	neutral	4,69	neutral	-0,93	deleterious	-2,86	low_impact	1,47	damaging	0,42	damaging	0,19	deleterious	3,7	23,3	0,56	0,6	disease	0,53	disease	0,79	disease	0,63	disease	0,62	2	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,81	low_impact	-3,6	medium_impact	0,15	medium_impact	0,14	0,78	0,85	24,71	7,13	N	0,38	N	0,98	polymorphism	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12826	12826	G	A	MI.20293	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	490	164	A	T	Gcc/Acc	-5,32	0	0	probably_damaging	1	neutral	0,39	neutral	4,47	deleterious	-3,48	deleterious	-3,72	high_impact	3,53	damaging	0,42	damaging	0,14	deleterious	4,3	24	0,48	0,55	disease	0,82	disease	0,78	disease	0,58	disease	0,68	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,13	high_impact	2,02	0,68	0,85	24,71	7,13	N	0,41	N	0,94	polymorphism	0,96	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12826	12826	G	C	MI.20294	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	490	164	A	P	Gcc/Ccc	-5,32	0	0	probably_damaging	1	neutral	0,2	neutral	4,42	deleterious	-3,37	deleterious	-4,83	high_impact	3,58	damaging	0,49	damaging	0,08	deleterious	3,85	23,4	0,26	0,45	disease	0,84	disease	0,87	disease	0,77	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,1	high_impact	2,07	0,74	0,85	24,71	7,13	N	0,38	N	0,96	polymorphism	0,88	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12827	12827	C	T	MI.20295	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	491	164	A	V	gCc/gTc	4,08	1	0	probably_damaging	1	neutral	0,49	neutral	4,43	deleterious	-3,03	deleterious	-3,85	medium_impact	3,19	damaging	0,4	damaging	0,05	deleterious	4,48	24,2	0,53	0,6	disease	0,57	disease	0,81	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,22	medium_impact	1,71	0,7	0,85	24,71	7,13	P	0,68	P	0,76	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12827	12827	C	G	MI.20296	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	491	164	A	G	gCc/gGc	4,08	1	0	probably_damaging	1	neutral	0,34	neutral	4,45	deleterious	-3,38	deleterious	-3,9	high_impact	4,22	damaging	0,47	damaging	0,11	deleterious	3,98	23,6	0,41	0,5	disease	0,92	disease	0,78	disease	0,66	disease	0,8	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,07	high_impact	2,65	0,73	0,85	24,71	7,13	P	0,58	P	0,82	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12827	12827	C	A	MI.20297	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	491	164	A	D	gCc/gAc	4,08	1	0	probably_damaging	1	neutral	0,21	neutral	4,45	deleterious	-3,86	deleterious	-5,8	high_impact	3,73	neutral	0,6	damaging	0,09	deleterious	4,47	24,2	0,28	0,45	disease	0,95	disease	0,9	disease	0,78	disease	0,85	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,09	high_impact	2,2	0,5	0,8	24,71	7,13	P	0,57	P	0,95	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12829	12829	A	T	MI.20298	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	493	165	N	Y	Aac/Tac	-11,28	0	0	probably_damaging	1	neutral	1	neutral	4,61	neutral	-0,86	deleterious	-7,89	medium_impact	2,4	neutral	0,63	damaging	0,1	deleterious	3,74	23,3	0,54	0,6	disease	0,64	disease	0,75	disease	0,68	disease	0,67	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,8	low_impact	-3,6	high_impact	1,89	medium_impact	0,99	0,33	0,8	28,36	7,2	N	0,19	N	0,99	polymorphism	0,94	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12829	12829	A	G	MI.20299	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	493	165	N	D	Aac/Gac	-11,28	0	0	probably_damaging	1	neutral	0,21	neutral	4,58	neutral	-2,59	deleterious	-4,93	medium_impact	3,5	neutral	0,72	damaging	0,1	deleterious	3,84	23,4	0,66	0,7	disease	0,72	disease	0,6	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	-0,09	medium_impact	1,99	0,34	0,8	28,36	7,2	N	0,33	N	0,94	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8621	8621	C	A	MI.203	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	95	32	P	H	cCc/cAc	0,13	0	0	probably_damaging	1	neutral	0,1	neutral	4,4	neutral	0,25	deleterious	-7,25	medium_impact	2,51	neutral	0,87	damaging	0,17	deleterious	3,89	23,5	0,41	0,65	disease	0,76	disease	0,8	neutral	0,49	disease	0,59	2	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	-0,25	medium_impact	1,05	0,5	0,9	29,2	19,38	N	0,31	N	0,9	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5974	5974	C	T	MI.2030	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	71	24	A	V	gCa/gTa	3,6	1	0	benign	0,11	neutral	0,35	neutral	2,92	neutral	1,1	neutral	-0,06	neutral_impact	0,07	damaging	0,6	neutral	0,61	neutral	0,89	10,01	0,34	0,55	neutral	0,2	neutral	0,48	neutral	0,22	neutral	0,44	1	neutral	0,6	deleterious	0,62	neutral	-6	neutral	0,3	medium_impact	0,1	medium_impact	0,04	low_impact	-1,03	0,76	0,9	3,12	8,36	P	0,53	P	0,75	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12829	12829	A	C	MI.20300	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	493	165	N	H	Aac/Cac	-11,28	0	0	probably_damaging	1	neutral	0,54	neutral	4,58	neutral	-2,28	deleterious	-4,93	high_impact	3,63	neutral	0,69	damaging	0,08	deleterious	3,04	22,3	0,63	0,65	disease	0,85	disease	0,56	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,27	high_impact	2,11	0,39	0,8	28,36	7,2	N	0,25	N	0,97	polymorphism	0,98	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12830	12830	A	G	MI.20301	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	494	165	N	S	aAc/aGc	5,46	1	0	probably_damaging	1	neutral	0,43	neutral	4,67	neutral	0,37	deleterious	-4,93	low_impact	1,54	neutral	0,88	damaging	0,09	deleterious	3,12	22,6	0,75	0,8	neutral	0,45	disease	0,56	disease	0,63	neutral	0,48	0	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,17	medium_impact	0,2	0,22	0,8	28,36	7,2	N	0,47	N	0,82	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12830	12830	A	C	MI.20302	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	494	165	N	T	aAc/aCc	5,46	1	0	probably_damaging	1	neutral	0,39	neutral	4,68	neutral	0,54	deleterious	-5,92	medium_impact	1,99	neutral	0,72	damaging	0,09	deleterious	3,43	23	0,68	0,7	disease	0,54	disease	0,6	disease	0,63	disease	0,57	1	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,13	medium_impact	0,62	0,44	0,8	28,36	7,2	N	0,41	N	0,94	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12830	12830	A	T	MI.20303	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	494	165	N	I	aAc/aTc	5,46	1	0	probably_damaging	1	neutral	0,43	neutral	4,73	neutral	1,13	deleterious	-8,88	medium_impact	2,94	neutral	0,68	damaging	0,09	deleterious	4,05	23,7	0,51	0,6	disease	0,74	disease	0,8	disease	0,66	disease	0,61	2	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,17	medium_impact	1,48	0,28	0,8	28,36	7,2	N	0,44	N	0,99	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12831	12831	C	G	MI.20304	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	495	165	N	K	aaC/aaG	5,46	1	0	probably_damaging	1	neutral	0,29	neutral	4,62	neutral	-0,51	deleterious	-5,92	medium_impact	3,29	neutral	0,69	damaging	0,09	deleterious	3,91	23,5	0,67	0,7	disease	0,55	disease	0,65	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,02	medium_impact	1,8	0,5	0,8	28,36	7,2	P	0,52	P	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12831	12831	C	A	MI.20305	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	495	165	N	K	aaC/aaA	5,46	1	0	probably_damaging	1	neutral	0,29	neutral	4,62	neutral	-0,51	deleterious	-5,92	medium_impact	3,29	neutral	0,69	damaging	0,09	deleterious	4,36	24,1	0,67	0,7	disease	0,55	disease	0,65	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,02	medium_impact	1,8	0,5	0,8	28,36	7,2	P	0,53	P	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12832	12832	A	G	MI.20306	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	496	166	T	A	Aca/Gca	-1,65	0	0	probably_damaging	1	neutral	0,56	neutral	4,66	neutral	0,26	deleterious	-4,93	neutral_impact	0,6	neutral	0,72	damaging	0,25	deleterious	3,36	22,9	0,61	0,65	neutral	0,32	neutral	0,38	neutral	0,22	neutral	0,45	1	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	0,29	medium_impact	-0,66	0,39	0,8	26,87	7,18	N	0,25	N	0,69	disease_causing	0,54	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12832	12832	A	T	MI.20307	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	496	166	T	S	Aca/Tca	-1,65	0	0	probably_damaging	1	neutral	0,45	neutral	4,69	neutral	0,6	deleterious	-3,95	neutral_impact	-0,12	neutral	0,74	neutral	0,29	deleterious	3,16	22,6	0,5	0,6	disease	0,54	neutral	0,45	neutral	0,19	neutral	0,48	0	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,18	low_impact	-1,31	0,59	0,8	26,87	7,18	N	0,35	N	0,89	polymorphism	0,72	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12832	12832	A	C	MI.20308	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	496	166	T	P	Aca/Cca	-1,65	0	0	probably_damaging	1	neutral	0,22	neutral	4,57	neutral	-2,07	deleterious	-5,92	medium_impact	3,14	neutral	0,68	damaging	0,11	deleterious	3,43	23	0,21	0,45	disease	0,81	disease	0,82	disease	0,57	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	-0,07	medium_impact	1,67	0,46	0,8	26,87	7,18	N	0,27	N	0,97	disease_causing	0,86	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12833	12833	C	A	MI.20309	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	497	166	T	K	aCa/aAa	5,46	1	0	probably_damaging	1	neutral	0,35	neutral	4,73	neutral	0,95	deleterious	-5,92	neutral_impact	0,62	neutral	0,72	damaging	0,17	deleterious	4,48	24,2	0,36	0,5	neutral	0,4	disease	0,66	disease	0,54	neutral	0,48	0	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,08	medium_impact	-0,64	0,67	0,85	26,87	7,18	N	0,39	N	1	disease_causing	0,97	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5976	5976	T	C	MI.2031	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	73	25	W	R	Tga/Cga	-2,88	0	0	probably_damaging	1	deleterious	0	neutral	2,77	neutral	-2,13	deleterious	-6,6	high_impact	4,77	neutral	0,65	damaging	0,04	deleterious	3,37	22,9	0,36	0,55	disease	0,59	disease	0,92	disease	0,76	disease	0,83	7	deleterious	1	deleterious	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,31	0,35	0,9	1,95	6,97	P	0,62	P	0,98	polymorphism	0,74	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12833	12833	C	T	MI.20310	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	497	166	T	M	aCa/aTa	5,46	1	0	probably_damaging	1	neutral	0,23	neutral	4,56	neutral	-2,62	deleterious	-5,92	medium_impact	2,04	neutral	0,73	damaging	0,15	deleterious	4,03	23,7	0,36	0,5	disease	0,86	disease	0,66	neutral	0,35	disease	0,61	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	-0,06	medium_impact	0,66	0,61	0,8	26,87	7,18	N	0,45	N	0,93	disease_causing	0,95	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12835	12835	G	T	MI.20311	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	499	167	A	S	Gca/Tca	-6,47	0	0	probably_damaging	1	neutral	0,43	neutral	4,36	deleterious	-3,27	deleterious	-2,76	neutral_impact	0,79	neutral	0,69	neutral	0,39	deleterious	3,69	23,3	0,33	0,5	disease	0,73	disease	0,63	neutral	0,3	neutral	0,47	1	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,84	low_impact	-3,6	medium_impact	0,17	medium_impact	-0,48	0,71	0,85	26,37	7,13	N	0,24	N	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12835	12835	G	A	MI.20312	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	499	167	A	T	Gca/Aca	-6,47	0	0	probably_damaging	1	neutral	0,4	neutral	4,21	deleterious	-5,2	deleterious	-3,81	high_impact	4,22	neutral	0,61	damaging	0,09	deleterious	4,21	23,9	0,32	0,5	disease	0,88	disease	0,81	disease	0,64	disease	0,76	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,14	high_impact	2,65	0,65	0,8	26,37	7,13	N	0,31	N	0,94	polymorphism	0,99	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12835	12835	G	C	MI.20313	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	499	167	A	P	Gca/Cca	-6,47	0	0	probably_damaging	1	neutral	0,2	neutral	4,2	deleterious	-6,44	deleterious	-4,83	medium_impact	3,14	neutral	0,61	damaging	0,07	deleterious	3,88	23,5	0,18	0,45	disease	0,95	disease	0,88	disease	0,75	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,92	low_impact	-3,6	medium_impact	-0,1	medium_impact	1,67	0,52	0,8	26,37	7,13	N	0,27	N	0,96	polymorphism	0,97	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12836	12836	C	T	MI.20314	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	500	167	A	V	gCa/gTa	3,85	1	0	probably_damaging	1	neutral	0,49	neutral	4,21	deleterious	-5,41	deleterious	-3,91	high_impact	4,78	damaging	0,56	damaging	0,07	deleterious	4,41	24,1	0,36	0,5	disease	0,75	disease	0,81	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,22	high_impact	3,16	0,69	0,85	26,37	7,13	P	0,69	P	0,76	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12836	12836	C	A	MI.20315	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	500	167	A	E	gCa/gAa	3,85	1	0	probably_damaging	1	neutral	0,27	neutral	4,23	deleterious	-4,42	deleterious	-4,8	high_impact	4,78	neutral	0,62	damaging	0,08	deleterious	4,5	24,3	0,14	0,4	disease	0,86	disease	0,88	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,01	high_impact	3,16	0,61	0,8	26,37	7,13	P	0,75	P	0,99	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12836	12836	C	G	MI.20316	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	500	167	A	G	gCa/gGa	3,85	1	0	probably_damaging	1	neutral	0,34	neutral	4,23	deleterious	-3,77	deleterious	-3,85	medium_impact	2,64	neutral	0,62	damaging	0,12	deleterious	3,92	23,5	0,23	0,45	disease	0,7	disease	0,78	disease	0,63	disease	0,62	2	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,07	medium_impact	1,21	0,75	0,85	26,37	7,13	N	0,44	N	0,82	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12838	12838	G	T	MI.20317	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	502	168	A	S	Gcc/Tcc	-7,16	0	0	probably_damaging	1	neutral	0,41	neutral	4,74	neutral	-2,52	deleterious	-2,96	medium_impact	2,02	damaging	0,47	damaging	0,22	deleterious	3,7	23,3	0,21	0,45	disease	0,73	disease	0,84	neutral	0,49	disease	0,53	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,15	medium_impact	0,64	0,7	0,85	28,36	7,07	N	0,31	N	0,98	polymorphism	0,96	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12838	12838	G	C	MI.20318	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	502	168	A	P	Gcc/Ccc	-7,16	0	0	probably_damaging	1	neutral	0,21	neutral	4,4	deleterious	-6,48	deleterious	-4,93	high_impact	4,88	damaging	0,51	damaging	0,1	deleterious	3,86	23,4	0,14	0,4	disease	0,96	disease	0,9	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	-0,09	high_impact	3,26	0,51	0,8	28,36	7,07	P	0,6	P	0,96	polymorphism	0,77	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12838	12838	G	A	MI.20319	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	502	168	A	T	Gcc/Acc	-7,16	0	0	probably_damaging	1	neutral	0,4	neutral	4,51	deleterious	-3,87	deleterious	-3,95	high_impact	4,88	damaging	0,49	damaging	0,08	deleterious	4,23	23,9	0,23	0,45	disease	0,78	disease	0,86	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,14	high_impact	3,26	0,61	0,8	28,36	7,07	P	0,64	P	0,94	polymorphism	0,92	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5976	5976	T	G	MI.2032	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	73	25	W	G	Tga/Gga	-2,88	0	0	probably_damaging	1	deleterious	0,02	neutral	2,81	neutral	-2,69	deleterious	-6,11	medium_impact	3,38	neutral	0,66	damaging	0,06	deleterious	3,74	23,3	0,28	0,55	neutral	0,37	disease	0,83	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,73	low_impact	-3,58	medium_impact	-0,75	high_impact	2,02	0,33	0,9	1,95	6,97	N	0,27	N	0,89	polymorphism	0,5	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12839	12839	C	G	MI.20320	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	503	168	A	G	gCc/gGc	5,92	1	0	probably_damaging	1	neutral	0,34	neutral	4,63	neutral	-1,89	deleterious	-3,95	low_impact	1,5	damaging	0,49	damaging	0,14	deleterious	3,96	23,6	0,22	0,45	disease	0,66	disease	0,84	disease	0,58	disease	0,64	3	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,83	low_impact	-3,6	medium_impact	0,07	medium_impact	0,17	0,75	0,85	28,36	7,07	P	0,51	P	0,82	disease_causing	0,88	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12839	12839	C	T	MI.20321	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	503	168	A	V	gCc/gTc	5,92	1	0	probably_damaging	1	neutral	0,5	neutral	4,47	deleterious	-4,5	deleterious	-3,95	high_impact	4,88	damaging	0,4	damaging	0,07	deleterious	4,43	24,2	0,26	0,45	disease	0,83	disease	0,86	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,23	high_impact	3,26	0,67	0,85	28,36	7,07	P	0,76	P	0,76	disease_causing	0,9	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12839	12839	C	A	MI.20322	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	503	168	A	D	gCc/gAc	5,92	1	0	probably_damaging	1	neutral	0,22	neutral	4,41	deleterious	-5,57	deleterious	-5,92	high_impact	4,88	damaging	0,59	damaging	0,1	deleterious	4,62	24,5	0,1	0,4	disease	0,96	disease	0,93	disease	0,68	disease	0,81	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	-0,07	high_impact	3,26	0,52	0,8	28,36	7,07	P	0,68	P	0,95	disease_causing	0,98	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12841	12841	A	C	MI.20323	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	505	169	I	L	Att/Ctt	-1,65	0	0	benign	0,01	neutral	0,68	neutral	4,79	neutral	0,89	neutral	1,73	neutral_impact	-1,84	neutral	0,72	neutral	0,94	neutral	-0,84	0,04	0,25	0,45	neutral	0,35	neutral	0,13	neutral	0,1	neutral	0,27	5	neutral	0,29	deleterious	0,84	neutral	-6	neutral	0,14	medium_impact	1,15	medium_impact	0,41	low_impact	-2,88	0,58	0,8	17,25	18,65	N	0,39	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12841	12841	A	G	MI.20324	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	505	169	I	V	Att/Gtt	-1,65	0	0	benign	0,01	neutral	0,51	neutral	4,57	neutral	-0,7	neutral	-0,87	neutral_impact	0,22	neutral	0,76	neutral	0,66	neutral	1,13	11,35	0,52	0,6	disease	0,59	neutral	0,39	neutral	0,33	disease	0,61	2	neutral	0,47	deleterious	0,75	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,24	low_impact	-1	0,46	0,8	17,25	18,65	N	0,28	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12841	12841	A	T	MI.20325	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	505	169	I	F	Att/Ttt	-1,65	0	0	possibly_damaging	0,61	neutral	0,7	neutral	4,61	neutral	-0,28	neutral	-1,92	neutral_impact	0,61	neutral	0,67	neutral	0,56	deleterious	2,43	19,03	0,36	0,5	disease	0,58	disease	0,8	neutral	0,49	disease	0,66	3	neutral	0,53	deleterious	0,55	neutral	-3	deleterious	0,57	medium_impact	-0,93	medium_impact	0,44	medium_impact	-0,65	0,56	0,8	17,25	18,65	N	0,23	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12842	12842	T	A	MI.20326	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	506	169	I	N	aTt/aAt	0,18	0,01	0	possibly_damaging	0,9	neutral	0,33	neutral	4,47	deleterious	-3,39	deleterious	-4,76	low_impact	0,84	neutral	0,67	neutral	0,5	deleterious	4,23	23,9	0,35	0,5	disease	0,79	disease	0,86	neutral	0,48	disease	0,78	6	neutral	0,91	neutral	0,22	neutral	-3	deleterious	0,77	low_impact	-1,65	medium_impact	0,06	medium_impact	-0,44	0,46	0,8	17,25	18,65	N	0,29	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12842	12842	T	G	MI.20327	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	506	169	I	S	aTt/aGt	0,18	0,01	0	possibly_damaging	0,75	neutral	0,42	neutral	4,5	neutral	-2,16	deleterious	-3,78	low_impact	1,3	neutral	0,71	neutral	0,68	deleterious	3,94	23,5	0,39	0,5	disease	0,69	disease	0,77	neutral	0,49	disease	0,62	2	neutral	0,75	neutral	0,34	neutral	-3	deleterious	0,62	low_impact	-1,2	medium_impact	0,16	medium_impact	-0,02	0,39	0,8	17,25	18,65	N	0,26	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12842	12842	T	C	MI.20328	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	506	169	I	T	aTt/aCt	0,18	0,01	0	possibly_damaging	0,48	neutral	0,41	neutral	4,55	neutral	-0,98	deleterious	-2,9	neutral_impact	0,76	neutral	0,68	neutral	0,52	neutral	1,62	13,98	0,48	0,55	disease	0,56	disease	0,6	neutral	0,47	disease	0,51	0	neutral	0,56	neutral	0,47	neutral	-3	deleterious	0,49	medium_impact	-0,71	medium_impact	0,15	medium_impact	-0,51	0,5	0,8	17,25	18,65	N	0,26	N	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12843	12843	T	G	MI.20329	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	507	169	I	M	atT/atG	7,3	0,95	0	benign	0,17	neutral	0,22	neutral	4,62	neutral	-0,2	neutral	0,36	neutral_impact	-1,33	neutral	0,75	neutral	0,88	deleterious	0,45	7,07	0,42	0,5	neutral	0,47	neutral	0,38	neutral	0,15	neutral	0,47	1	neutral	0,74	deleterious	0,53	neutral	-6	neutral	0,19	medium_impact	-0,09	medium_impact	-0,07	low_impact	-2,42	0,56	0,8	17,25	18,65	P	0,57	P	0,62	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5977	5977	G	C	MI.2033	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	74	25	W	S	tGa/tCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,82	neutral	-1,63	deleterious	-6,56	high_impact	3,96	neutral	0,65	damaging	0,05	deleterious	3,85	23,4	0,28	0,55	neutral	0,32	disease	0,89	disease	0,7	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,56	0,34	0,9	1,95	6,97	N	0,45	N	0,89	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12843	12843	T	A	MI.20330	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	507	169	I	M	atT/atA	7,3	0,95	0	benign	0,17	neutral	0,22	neutral	4,62	neutral	-0,2	neutral	0,36	neutral_impact	-1,33	neutral	0,75	neutral	0,88	deleterious	0,72	8,97	0,42	0,5	neutral	0,47	neutral	0,38	neutral	0,15	neutral	0,47	1	neutral	0,74	deleterious	0,53	neutral	-6	neutral	0,19	medium_impact	-0,09	medium_impact	-0,07	low_impact	-2,42	0,56	0,8	17,25	18,65	P	0,56	P	0,62	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12844	12844	C	A	MI.20331	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	508	170	Q	K	Caa/Aaa	-6,93	0	0	probably_damaging	1	neutral	0,29	neutral	4,99	neutral	3,54	deleterious	-3,95	low_impact	1,23	damaging	0,47	damaging	0,05	deleterious	3,94	23,5	0,55	0,6	neutral	0,34	disease	0,77	disease	0,69	disease	0,52	0	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,02	medium_impact	-0,08	0,62	0,8	27,69	7,2	N	0,28	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12844	12844	C	G	MI.20332	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	508	170	Q	E	Caa/Gaa	-6,93	0	0	probably_damaging	1	neutral	0,28	neutral	4,65	neutral	-0,28	deleterious	-2,96	medium_impact	2,31	damaging	0,49	damaging	0,05	deleterious	3,12	22,6	0,64	0,7	disease	0,72	disease	0,82	disease	0,6	disease	0,62	2	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,01	medium_impact	0,91	0,7	0,85	27,69	7,2	N	0,28	N	0,92	polymorphism	1	0,09	rs28668242	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12845	12845	A	C	MI.20333	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	509	170	Q	P	cAa/cCa	4,31	0,99	0	probably_damaging	1	neutral	0,19	neutral	4,6	neutral	-2,7	deleterious	-5,93	high_impact	4,32	damaging	0,48	damaging	0,05	deleterious	3,35	22,9	0,27	0,45	disease	0,92	disease	0,92	disease	0,75	disease	0,84	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	-0,12	high_impact	2,74	0,64	0,8	27,69	7,2	P	0,54	P	0,95	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12845	12845	A	T	MI.20334	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	509	170	Q	L	cAa/cTa	4,31	0,99	0	probably_damaging	1	neutral	0,72	neutral	4,68	neutral	-0,9	deleterious	-6,92	medium_impact	2,15	damaging	0,51	damaging	0,04	deleterious	3,81	23,4	0,4	0,5	disease	0,68	disease	0,91	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,46	medium_impact	0,76	0,32	0,8	27,69	7,2	N	0,39	N	0,96	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12845	12845	A	G	MI.20335	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	509	170	Q	R	cAa/cGa	4,31	0,99	0	probably_damaging	1	neutral	0,33	neutral	4,66	neutral	0,54	deleterious	-3,95	medium_impact	2,7	damaging	0,51	damaging	0,03	deleterious	3,46	23	0,64	0,7	disease	0,79	disease	0,88	disease	0,68	disease	0,75	5	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,88	low_impact	-3,6	medium_impact	0,06	medium_impact	1,26	0,54	0,8	27,69	7,2	N	0,41	N	0,85	disease_causing	0,97	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12846	12846	A	C	MI.20336	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	510	170	Q	H	caA/caC	6,84	1	0	probably_damaging	1	neutral	0,51	neutral	4,61	neutral	-2,03	deleterious	-4,94	high_impact	3,62	damaging	0,54	damaging	0,03	deleterious	3,46	23	0,58	0,65	disease	0,9	disease	0,81	disease	0,68	disease	0,77	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,24	high_impact	2,1	0,63	0,8	27,69	7,2	N	0,49	N	0,94	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12846	12846	A	T	MI.20337	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	510	170	Q	H	caA/caT	6,84	1	0	probably_damaging	1	neutral	0,51	neutral	4,61	neutral	-2,03	deleterious	-4,94	high_impact	3,62	damaging	0,54	damaging	0,03	deleterious	3,6	23,2	0,58	0,65	disease	0,9	disease	0,81	disease	0,68	disease	0,77	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,24	high_impact	2,1	0,63	0,8	27,69	7,2	N	0,51	P	0,94	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12847	12847	G	C	MI.20338	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	511	171	A	P	Gca/Cca	-0,27	0,23	0	probably_damaging	1	neutral	0,21	neutral	4,44	deleterious	-6,1	deleterious	-4,94	high_impact	5	damaging	0,25	damaging	0,26	deleterious	3,86	23,5	0,18	0,45	disease	0,94	disease	0,92	disease	0,78	disease	0,85	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	-0,09	high_impact	3,36	0,81	0,85	27,2	7,21	P	0,92	P	0,96	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12847	12847	G	T	MI.20339	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	511	171	A	S	Gca/Tca	-0,27	0,23	0	probably_damaging	1	neutral	0,42	neutral	4,47	deleterious	-3,19	deleterious	-2,96	medium_impact	3,27	damaging	0,3	neutral	0,35	deleterious	3,7	23,3	0,36	0,5	disease	0,81	disease	0,9	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,89	low_impact	-3,6	medium_impact	0,16	medium_impact	1,78	0,84	0,9	27,2	7,21	P	0,64	P	0,98	disease_causing	0,99	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5977	5977	G	T	MI.2034	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	74	25	W	L	tGa/tTa	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	2,99	neutral	0,19	deleterious	-6,11	medium_impact	3,16	neutral	0,69	damaging	0,03	deleterious	4,06	23,7	0,25	0,55	neutral	0,2	disease	0,86	disease	0,55	disease	0,56	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,72	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,82	0,24	0,9	1,95	6,97	N	0,42	N	0,95	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12847	12847	G	A	MI.20340	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	511	171	A	T	Gca/Aca	-0,27	0,23	0	probably_damaging	1	neutral	0,48	neutral	4,53	deleterious	-3,52	deleterious	-3,95	medium_impact	2,32	damaging	0,26	damaging	0,21	deleterious	4,27	24	0,45	0,55	disease	0,55	disease	0,88	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,21	medium_impact	0,92	0,65	0,8	27,2	7,21	P	0,86	P	0,94	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12848	12848	C	G	MI.20341	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	512	171	A	G	gCa/gGa	7,3	1	0	probably_damaging	1	neutral	0,38	neutral	4,45	deleterious	-4,27	deleterious	-3,95	high_impact	3,9	damaging	0,25	neutral	0,37	deleterious	3,92	23,5	0,25	0,45	disease	0,92	disease	0,87	disease	0,65	disease	0,81	6	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,12	high_impact	2,36	0,87	0,9	27,2	7,21	P	0,94	P	0,82	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12848	12848	C	A	MI.20342	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	512	171	A	E	gCa/gAa	7,3	1	0	probably_damaging	1	neutral	0,33	neutral	4,45	deleterious	-5,34	deleterious	-4,94	high_impact	5	damaging	0,28	damaging	0,26	deleterious	4,53	24,3	0,13	0,4	disease	0,92	disease	0,93	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	0,06	high_impact	3,36	0,73	0,85	27,2	7,21	P	0,92	P	0,99	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12848	12848	C	T	MI.20343	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	512	171	A	V	gCa/gTa	7,3	1	0	probably_damaging	1	neutral	0,5	neutral	4,53	deleterious	-3,25	deleterious	-3,95	high_impact	4,46	damaging	0,13	damaging	0,2	deleterious	4,41	24,1	0,52	0,6	disease	0,76	disease	0,9	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,23	high_impact	2,87	0,72	0,85	27,2	7,21	P	0,95	P	0,76	disease_causing_automatic	1	0,26	rs267606899	Pathogenic	Leber's_optic_atrophy	RCV000010350.2	MedGen:OMIM:SNOMED_CT	.	.	.	.	C12848T	LHON	-	+	Reported	3
chrM	12850	12850	A	C	MI.20344	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	514	172	I	L	Atc/Ctc	-5,55	0	0	possibly_damaging	0,61	neutral	0,67	neutral	4,65	neutral	1,03	neutral	-1,8	low_impact	1,55	neutral	0,71	neutral	0,4	deleterious	3,75	23,3	0,36	0,5	neutral	0,37	disease	0,73	disease	0,58	disease	0,7	4	neutral	0,53	deleterious	0,53	neutral	-3	deleterious	0,69	medium_impact	-0,93	medium_impact	0,4	medium_impact	0,21	0,64	0,8	6,8	9,63	N	0,23	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12850	12850	A	T	MI.20345	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	514	172	I	F	Atc/Ttc	-5,55	0	0	probably_damaging	0,97	neutral	0,7	neutral	4,83	neutral	2,01	deleterious	-3,77	low_impact	1,28	neutral	0,65	neutral	0,37	deleterious	3,83	23,4	0,37	0,5	neutral	0,37	disease	0,81	disease	0,64	disease	0,56	1	neutral	0,97	neutral	0,37	neutral	-2	deleterious	0,75	low_impact	-2,18	medium_impact	0,44	medium_impact	-0,03	0,75	0,85	6,8	9,63	N	0,27	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12850	12850	A	G	MI.20346	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	514	172	I	V	Atc/Gtc	-5,55	0	0	benign	0,12	neutral	0,52	neutral	4,6	neutral	-0,23	neutral	-0,52	neutral_impact	0,35	neutral	0,84	neutral	0,99	deleterious	0,26	5,29	0,53	0,6	disease	0,5	neutral	0,07	neutral	0,28	neutral	0,18	6	neutral	0,39	deleterious	0,7	neutral	-6	deleterious	0,63	medium_impact	0,08	medium_impact	0,25	medium_impact	-0,88	0,61	0,8	6,8	9,63	N	0,33	N	0,25	polymorphism	1	0,02	rs28705385	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12851	12851	T	A	MI.20347	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	515	172	I	N	aTc/aAc	-0,04	0,02	0	probably_damaging	0,98	neutral	0,34	neutral	4,46	deleterious	-4,1	deleterious	-6,47	high_impact	4,03	neutral	0,67	neutral	0,36	deleterious	4,56	24,4	0,17	0,45	disease	0,9	disease	0,91	disease	0,6	disease	0,8	6	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-2,35	medium_impact	0,07	high_impact	2,48	0,61	0,8	6,8	9,63	N	0,37	N	0,98	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12851	12851	T	G	MI.20348	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	515	172	I	S	aTc/aGc	-0,04	0,02	0	probably_damaging	0,96	neutral	0,44	neutral	4,49	neutral	-2,53	deleterious	-5,48	medium_impact	3,48	neutral	0,69	neutral	0,42	deleterious	4,23	23,9	0,22	0,45	disease	0,51	disease	0,87	disease	0,6	disease	0,76	5	neutral	0,96	neutral	0,24	deleterious	1	deleterious	0,81	low_impact	-2,06	medium_impact	0,18	medium_impact	1,98	0,56	0,8	6,8	9,63	N	0,32	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12851	12851	T	C	MI.20349	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	515	172	I	T	aTc/aCc	-0,04	0,02	0	probably_damaging	0,91	neutral	0,42	neutral	4,52	neutral	-1,77	deleterious	-4,35	high_impact	4,03	neutral	0,66	neutral	0,37	deleterious	3,41	23	0,38	0,5	disease	0,75	disease	0,75	disease	0,57	disease	0,71	4	neutral	0,91	neutral	0,26	deleterious	2	deleterious	0,81	low_impact	-1,7	medium_impact	0,16	high_impact	2,48	0,65	0,8	6,8	9,63	N	0,36	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5978	5978	A	C	MI.2035	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	75	25	W	C	tgA/tgC	9,38	1	0,01	probably_damaging	1	deleterious	0	neutral	2,77	deleterious	-4,04	deleterious	-6,11	high_impact	3,8	damaging	0,6	damaging	0,04	deleterious	3,86	23,5	0,31	0,55	disease	0,65	disease	0,92	disease	0,68	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,41	0,32	0,9	1,95	6,97	N	0,43	N	0,88	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12852	12852	C	A	MI.20350	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	516	172	I	M	atC/atA	7,3	0,95	0	probably_damaging	0,97	neutral	0,23	neutral	4,52	neutral	-0,62	neutral	-2,34	low_impact	1,32	neutral	0,77	neutral	0,95	deleterious	2,78	21,3	0,4	0,5	disease	0,7	disease	0,54	neutral	0,38	disease	0,51	0	neutral	0,98	neutral	0,13	neutral	-2	deleterious	0,76	low_impact	-2,18	medium_impact	-0,06	medium_impact	0	0,76	0,85	6,8	9,63	N	0,47	N	0,76	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12852	12852	C	G	MI.20351	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	516	172	I	M	atC/atG	7,3	0,95	0	probably_damaging	0,97	neutral	0,23	neutral	4,52	neutral	-0,62	neutral	-2,34	low_impact	1,32	neutral	0,77	neutral	0,95	deleterious	2,31	18,25	0,4	0,5	disease	0,7	disease	0,54	neutral	0,38	disease	0,51	0	neutral	0,98	neutral	0,13	neutral	-2	deleterious	0,76	low_impact	-2,18	medium_impact	-0,06	medium_impact	0	0,76	0,85	6,8	9,63	N	0,47	N	0,76	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12853	12853	C	G	MI.20352	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	517	173	L	V	Cta/Gta	-7,84	0	0	probably_damaging	1	neutral	0,57	neutral	4,25	neutral	-1,07	deleterious	-2,71	low_impact	1,61	neutral	0,8	neutral	0,43	deleterious	2,26	17,88	0,4	0,5	disease	0,6	neutral	0,5	neutral	0,36	neutral	0,49	0	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	0,3	medium_impact	0,27	0,72	0,85	11,44	6,92	N	0,2	N	0,62	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12853	12853	C	A	MI.20353	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	517	173	L	M	Cta/Ata	-7,84	0	0	probably_damaging	1	neutral	0,32	neutral	4,11	deleterious	-3,38	neutral	-1,91	medium_impact	2,44	neutral	0,77	damaging	0,28	deleterious	3,62	23,2	0,33	0,5	disease	0,89	disease	0,53	neutral	0,38	disease	0,64	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,05	medium_impact	1,03	0,74	0,85	11,44	6,92	N	0,28	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12854	12854	T	A	MI.20354	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	518	173	L	Q	cTa/cAa	-2,11	0	0	probably_damaging	1	neutral	0,32	neutral	4,07	deleterious	-5,81	deleterious	-5,86	high_impact	4,2	neutral	0,73	damaging	0,1	deleterious	4,03	23,6	0,17	0,45	disease	0,8	disease	0,82	disease	0,58	disease	0,74	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,05	high_impact	2,63	0,73	0,85	11,44	6,92	N	0,32	N	0,97	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12854	12854	T	G	MI.20355	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	518	173	L	R	cTa/cGa	-2,11	0	0	probably_damaging	1	neutral	0,38	neutral	4,07	deleterious	-5,34	deleterious	-5,87	high_impact	4,2	neutral	0,68	damaging	0,08	deleterious	4,14	23,8	0,14	0,4	disease	0,93	disease	0,92	disease	0,7	disease	0,83	7	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,93	low_impact	-3,6	medium_impact	0,12	high_impact	2,63	0,56	0,8	11,44	6,92	N	0,3	N	0,96	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12854	12854	T	C	MI.20356	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	518	173	L	P	cTa/cCa	-2,11	0	0	probably_damaging	1	neutral	0,21	neutral	4,07	deleterious	-6,31	deleterious	-6,79	high_impact	3,86	neutral	0,64	damaging	0,08	deleterious	3,87	23,5	0,16	0,45	disease	0,71	disease	0,92	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,09	high_impact	2,32	0,68	0,85	11,44	6,92	N	0,29	N	0,89	polymorphism	1	0,31	.	.	.	.	.	.	COSM488735	.	.	.	.	.	.	.	.
chrM	12856	12856	T	A	MI.20357	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	520	174	Y	N	Tac/Aac	-6,7	0	0	probably_damaging	1	neutral	0,33	neutral	4,45	deleterious	-4,89	deleterious	-8,77	medium_impact	3,38	damaging	0,58	damaging	0,11	deleterious	3,92	23,5	0,33	0,5	disease	0,85	disease	0,93	disease	0,71	disease	0,79	6	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,06	medium_impact	1,88	0,53	0,8	15,42	7,13	N	0,3	N	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12856	12856	T	C	MI.20358	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	520	174	Y	H	Tac/Cac	-6,7	0	0	probably_damaging	1	neutral	0,5	neutral	4,45	deleterious	-5,37	deleterious	-4,9	high_impact	4,08	neutral	0,61	damaging	0,08	deleterious	3,48	23,1	0,4	0,5	disease	0,93	disease	0,9	disease	0,79	disease	0,85	7	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,23	high_impact	2,52	0,68	0,85	15,42	7,13	N	0,36	N	0,98	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12856	12856	T	G	MI.20359	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	520	174	Y	D	Tac/Gac	-6,7	0	0	probably_damaging	1	neutral	0,22	neutral	4,44	deleterious	-6,12	deleterious	-9,72	high_impact	4,08	neutral	0,64	damaging	0,11	deleterious	3,84	23,4	0,19	0,45	disease	0,95	disease	0,94	disease	0,78	disease	0,85	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,07	high_impact	2,52	0,55	0,8	15,42	7,13	N	0,38	N	0,96	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5978	5978	A	T	MI.2036	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	75	25	W	C	tgA/tgT	9,38	1	0,01	probably_damaging	1	deleterious	0	neutral	2,77	deleterious	-4,04	deleterious	-6,11	high_impact	3,8	damaging	0,6	damaging	0,04	deleterious	3,93	23,5	0,31	0,55	disease	0,65	disease	0,92	disease	0,68	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,41	0,32	0,9	1,95	6,97	N	0,44	N	0,88	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12857	12857	A	G	MI.20360	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	521	174	Y	C	tAc/tGc	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	4,45	deleterious	-4,33	deleterious	-8,73	medium_impact	3,38	neutral	0,61	damaging	0,08	deleterious	3,39	23	0,34	0,5	disease	0,92	disease	0,94	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,88	low_impact	-3,6	medium_impact	-0,13	medium_impact	1,88	0,36	0,8	15,42	7,13	N	0,48	N	1	disease_causing	0,87	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12857	12857	A	C	MI.20361	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	521	174	Y	S	tAc/tCc	7,3	1	0	probably_damaging	1	neutral	0,46	neutral	4,49	deleterious	-3,19	deleterious	-8,73	low_impact	1,9	neutral	0,64	damaging	0,12	deleterious	3,65	23,2	0,36	0,5	neutral	0,42	disease	0,92	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,83	low_impact	-3,6	medium_impact	0,19	medium_impact	0,53	0,66	0,8	15,42	7,13	N	0,4	N	0,97	disease_causing	0,81	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12857	12857	A	T	MI.20362	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	521	174	Y	F	tAc/tTc	7,3	1	0	probably_damaging	1	neutral	0,69	neutral	4,48	neutral	-1,56	deleterious	-3,67	medium_impact	2,42	damaging	0,58	damaging	0,14	deleterious	3,24	22,8	0,39	0,5	disease	0,74	disease	0,92	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,42	medium_impact	1,01	0,74	0,85	15,42	7,13	N	0,49	N	0,8	polymorphism	0,75	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12859	12859	A	T	MI.20363	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	523	175	N	Y	Aac/Tac	-4,86	0	0	probably_damaging	1	neutral	1	neutral	4,46	deleterious	-3,5	deleterious	-7,91	high_impact	5,03	damaging	0,32	damaging	0,2	deleterious	3,5	23,1	0,32	0,5	disease	0,81	disease	0,94	disease	0,73	disease	0,84	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,88	low_impact	-3,6	high_impact	1,89	high_impact	3,39	0,68	0,85	29,35	7,2	P	0,65	P	0,99	disease_causing	0,94	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12859	12859	A	C	MI.20364	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	523	175	N	H	Aac/Cac	-4,86	0	0	probably_damaging	1	neutral	0,54	neutral	4,47	deleterious	-4,25	deleterious	-4,94	high_impact	5,03	damaging	0,31	damaging	0,21	deleterious	2,95	22	0,41	0,5	disease	0,92	disease	0,89	disease	0,77	disease	0,85	7	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,27	high_impact	3,39	0,65	0,8	29,35	7,2	P	0,73	P	0,97	disease_causing	0,78	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12859	12859	A	G	MI.20365	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	523	175	N	D	Aac/Gac	-4,86	0	0	probably_damaging	1	neutral	0,24	neutral	4,5	deleterious	-4,31	deleterious	-4,94	high_impact	5,03	damaging	0,36	neutral	0,31	deleterious	3,68	23,3	0,5	0,6	disease	0,9	disease	0,88	disease	0,78	disease	0,83	7	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,04	high_impact	3,39	0,73	0,85	29,35	7,2	P	0,77	P	0,94	disease_causing	0,62	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12860	12860	A	C	MI.20366	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	524	175	N	T	aAc/aCc	6,84	1	0	probably_damaging	1	neutral	0,41	neutral	4,69	neutral	0,64	deleterious	-5,93	medium_impact	2,36	damaging	0,32	neutral	0,28	deleterious	3,79	23,4	0,55	0,6	neutral	0,47	disease	0,9	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,15	medium_impact	0,95	0,78	0,85	29,35	7,2	P	0,72	P	0,94	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12860	12860	A	T	MI.20367	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	524	175	N	I	aAc/aTc	6,84	1	0	probably_damaging	1	neutral	0,41	neutral	4,46	neutral	-2,52	deleterious	-8,89	high_impact	5,03	damaging	0,3	neutral	0,42	deleterious	4,37	24,1	0,36	0,5	disease	0,7	disease	0,96	disease	0,7	disease	0,83	7	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,15	high_impact	3,39	0,66	0,8	29,35	7,2	P	0,83	P	0,99	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12860	12860	A	G	MI.20368	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	524	175	N	S	aAc/aGc	6,84	1	0	probably_damaging	1	neutral	0,44	neutral	4,6	neutral	-1,52	deleterious	-4,94	high_impact	4,34	damaging	0,34	neutral	0,35	deleterious	3,55	23,1	0,67	0,7	disease	0,68	disease	0,89	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,18	high_impact	2,76	0,59	0,8	29,35	7,2	P	0,8	P	0,82	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12861	12861	C	A	MI.20369	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	525	175	N	K	aaC/aaA	8,44	1	0	probably_damaging	1	neutral	0,34	neutral	4,54	deleterious	-3,17	deleterious	-5,93	high_impact	3,5	damaging	0,3	damaging	0,25	deleterious	4,34	24	0,53	0,6	disease	0,74	disease	0,93	disease	0,76	disease	0,82	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,07	medium_impact	1,99	0,76	0,85	29,35	7,2	P	0,77	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5979	5979	G	C	MI.2037	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	76	26	A	P	Gct/Cct	-0,11	0,56	0	probably_damaging	1	deleterious	0,01	neutral	2,64	deleterious	-3,7	neutral	-1,92	high_impact	4,09	damaging	0,56	neutral	0,4	deleterious	3,7	23,3	0,12	0,55	disease	0,71	disease	0,91	disease	0,65	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,58	medium_impact	-0,92	high_impact	2,68	0,8	0,9	2,14	7,08	N	0,36	N	0,85	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12861	12861	C	G	MI.20370	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	525	175	N	K	aaC/aaG	8,44	1	0	probably_damaging	1	neutral	0,34	neutral	4,54	deleterious	-3,17	deleterious	-5,93	high_impact	3,5	damaging	0,3	damaging	0,25	deleterious	3,93	23,5	0,53	0,6	disease	0,74	disease	0,93	disease	0,76	disease	0,82	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,07	medium_impact	1,99	0,76	0,85	29,35	7,2	P	0,76	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12862	12862	C	G	MI.20371	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	526	176	R	G	Cgt/Ggt	-1,19	0,01	0	probably_damaging	1	neutral	0,37	neutral	4,54	neutral	-2,3	deleterious	-6,92	medium_impact	3,27	damaging	0,3	damaging	0,08	deleterious	4,12	23,8	0,34	0,5	disease	0,66	disease	0,88	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,11	medium_impact	1,78	0,46	0,8	28,69	7,19	P	0,56	P	0,97	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12862	12862	C	T	MI.20372	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	526	176	R	C	Cgt/Tgt	-1,19	0,01	0	probably_damaging	1	neutral	0,18	neutral	4,46	deleterious	-5,34	deleterious	-7,91	high_impact	4,76	damaging	0,38	damaging	0,04	deleterious	4,92	25	0,35	0,5	disease	0,96	disease	0,91	disease	0,73	disease	0,8	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,13	high_impact	3,15	0,76	0,85	28,69	7,19	P	0,58	P	1	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12862	12862	C	A	MI.20373	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	526	176	R	S	Cgt/Agt	-1,19	0,01	0	probably_damaging	1	neutral	0,47	neutral	4,55	neutral	-2,2	deleterious	-5,93	high_impact	4,21	damaging	0,39	damaging	0,07	deleterious	4,66	24,5	0,35	0,5	disease	0,72	disease	0,9	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,2	high_impact	2,64	0,51	0,8	28,69	7,19	P	0,52	P	0,82	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12863	12863	G	C	MI.20374	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	527	176	R	P	cGt/cCt	3,4	0,99	0	probably_damaging	1	neutral	0,22	neutral	4,47	deleterious	-5,28	deleterious	-6,92	high_impact	5,11	damaging	0,34	damaging	0,06	deleterious	4,19	23,8	0,28	0,45	disease	0,91	disease	0,93	disease	0,84	disease	0,82	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,07	high_impact	3,47	0,29	0,8	28,69	7,19	P	0,72	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12863	12863	G	A	MI.20375	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	527	176	R	H	cGt/cAt	3,4	0,99	0	probably_damaging	1	neutral	0,53	neutral	4,47	neutral	-2,96	deleterious	-4,94	high_impact	4,76	damaging	0,35	damaging	0,04	deleterious	4,32	24	0,58	0,65	disease	0,81	disease	0,88	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,26	high_impact	3,15	0,78	0,85	28,69	7,19	P	0,78	P	1	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12863	12863	G	T	MI.20376	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	527	176	R	L	cGt/cTt	3,4	0,99	0	probably_damaging	1	neutral	0,68	neutral	4,58	neutral	-1,01	deleterious	-6,92	high_impact	5,11	damaging	0,29	damaging	0,05	deleterious	4,26	23,9	0,38	0,5	disease	0,68	disease	0,96	disease	0,72	disease	0,82	6	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,41	high_impact	3,47	0,48	0,8	28,69	7,19	P	0,75	P	1	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12865	12865	A	C	MI.20377	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	529	177	I	L	Atc/Ctc	-4,4	0	0	probably_damaging	1	neutral	0,81	neutral	4,65	neutral	0,24	neutral	-1,92	low_impact	1,19	neutral	0,74	neutral	0,68	deleterious	3,75	23,3	0,39	0,5	neutral	0,46	disease	0,84	disease	0,51	disease	0,52	0	deleterious	1	neutral	0,41	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	0,58	medium_impact	-0,12	0,84	0,9	6,8	7,21	N	0,24	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12865	12865	A	G	MI.20378	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	529	177	I	V	Atc/Gtc	-4,4	0	0	probably_damaging	1	neutral	0,79	neutral	4,6	neutral	0,82	neutral	-0,96	neutral_impact	0,36	neutral	0,71	neutral	0,76	neutral	0,93	10,28	0,6	0,65	neutral	0,33	neutral	0,14	neutral	0,34	neutral	0,23	5	deleterious	1	neutral	0,4	neutral	-2	deleterious	0,63	low_impact	-3,6	medium_impact	0,55	medium_impact	-0,87	0,6	0,8	6,8	7,21	N	0,28	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12865	12865	A	T	MI.20379	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	529	177	I	F	Atc/Ttc	-4,4	0	0	probably_damaging	1	neutral	0,79	neutral	4,57	neutral	-0,56	deleterious	-3,89	low_impact	1,64	neutral	0,66	neutral	0,34	deleterious	3,79	23,4	0,44	0,55	disease	0,6	disease	0,92	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,4	neutral	-2	deleterious	0,84	low_impact	-3,6	medium_impact	0,55	medium_impact	0,3	0,77	0,85	6,8	7,21	N	0,18	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5979	5979	G	A	MI.2038	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	76	26	A	T	Gct/Act	-0,11	0,56	0	probably_damaging	1	deleterious	0,02	neutral	2,69	neutral	-1,58	neutral	-1,17	medium_impact	2,64	damaging	0,53	neutral	0,39	deleterious	4,01	23,6	0,41	0,55	neutral	0,37	disease	0,66	neutral	0,43	disease	0,52	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,73	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,34	0,8	0,9	2,14	7,08	N	0,41	N	0,2	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12866	12866	T	A	MI.20380	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	530	177	I	N	aTc/aAc	0,18	0,01	0	probably_damaging	1	neutral	0,63	neutral	4,39	deleterious	-4,74	deleterious	-6,83	high_impact	4,36	neutral	0,67	neutral	0,35	deleterious	4,32	24	0,31	0,45	disease	0,92	disease	0,94	disease	0,65	disease	0,82	6	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,36	high_impact	2,78	0,57	0,8	6,8	7,21	N	0,37	N	0,97	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12866	12866	T	G	MI.20381	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	530	177	I	S	aTc/aGc	0,18	0,01	0	probably_damaging	1	neutral	0,86	neutral	4,42	neutral	-2,79	deleterious	-5,84	medium_impact	3,46	neutral	0,69	neutral	0,4	deleterious	4,21	23,9	0,35	0,5	disease	0,76	disease	0,92	disease	0,64	disease	0,74	5	deleterious	1	neutral	0,43	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	0,67	medium_impact	1,96	0,5	0,8	6,8	7,21	N	0,25	N	0,94	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12866	12866	T	C	MI.20382	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	530	177	I	T	aTc/aCc	0,18	0,01	0	probably_damaging	1	neutral	0,74	neutral	4,46	neutral	-1,93	deleterious	-4,87	medium_impact	2,69	neutral	0,81	neutral	0,59	deleterious	3,36	22,9	0,58	0,65	disease	0,65	disease	0,82	disease	0,56	disease	0,64	3	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,48	medium_impact	1,25	0,68	0,85	6,8	7,21	N	0,2	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12867	12867	C	G	MI.20383	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	531	177	I	M	atC/atG	5,69	0,87	0	probably_damaging	1	neutral	0,4	neutral	4,43	neutral	-2,44	deleterious	-2,82	medium_impact	3,12	neutral	0,79	neutral	0,66	deleterious	3,27	22,8	0,47	0,55	disease	0,77	disease	0,77	disease	0,54	disease	0,58	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,14	medium_impact	1,65	0,85	0,9	6,8	7,21	N	0,41	N	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12867	12867	C	A	MI.20384	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	531	177	I	M	atC/atA	5,69	0,87	0	probably_damaging	1	neutral	0,4	neutral	4,43	neutral	-2,44	deleterious	-2,82	medium_impact	3,12	neutral	0,79	neutral	0,66	deleterious	3,77	23,4	0,47	0,55	disease	0,77	disease	0,77	disease	0,54	disease	0,58	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,14	medium_impact	1,65	0,85	0,9	6,8	7,21	N	0,41	N	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12868	12868	G	A	MI.20385	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	532	178	G	S	Ggc/Agc	-8,3	0	0	probably_damaging	1	neutral	0,5	neutral	4,49	deleterious	-3,21	deleterious	-5,93	medium_impact	3,44	damaging	0,4	damaging	0,11	deleterious	4,1	23,7	0,2	0,45	neutral	0,5	disease	0,91	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,23	medium_impact	1,94	0,77	0,85	29,02	7,24	N	0,43	N	1	disease_causing	0,85	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12868	12868	G	T	MI.20386	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	532	178	G	C	Ggc/Tgc	-8,3	0	0	probably_damaging	1	neutral	0,18	neutral	4,08	deleterious	-6,7	deleterious	-8,89	high_impact	5,17	damaging	0,38	damaging	0,08	deleterious	4,04	23,7	0,11	0,4	disease	0,98	disease	0,94	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,13	high_impact	3,52	0,54	0,8	29,02	7,24	P	0,51	P	0,97	disease_causing	0,96	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12868	12868	G	C	MI.20387	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	532	178	G	R	Ggc/Cgc	-8,3	0	0	probably_damaging	1	neutral	0,42	neutral	4,06	deleterious	-6,5	deleterious	-7,91	high_impact	4,82	damaging	0,42	damaging	0,09	deleterious	3,82	23,4	0,08	0,35	disease	0,89	disease	0,95	disease	0,84	disease	0,86	7	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,93	low_impact	-3,6	medium_impact	0,16	high_impact	3,2	0,61	0,8	29,02	7,24	P	0,58	P	1	disease_causing	0,92	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12869	12869	G	A	MI.20388	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	533	178	G	D	gGc/gAc	5,92	1	0	probably_damaging	1	neutral	0,28	neutral	4,05	deleterious	-6,81	deleterious	-6,92	high_impact	5,17	damaging	0,46	damaging	0,09	deleterious	3,75	23,3	0,08	0,35	disease	0,9	disease	0,94	disease	0,82	disease	0,86	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,01	high_impact	3,52	0,43	0,8	29,02	7,24	P	0,69	P	0,95	disease_causing	1	0,44	.	.	.	.	.	.	COSM1636303	.	.	.	.	.	.	.	.
chrM	12869	12869	G	T	MI.20389	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	533	178	G	V	gGc/gTc	5,92	1	0	probably_damaging	1	neutral	0,55	neutral	4,07	deleterious	-5,4	deleterious	-8,89	high_impact	5,17	damaging	0,32	damaging	0,08	deleterious	3,74	23,3	0,09	0,4	disease	0,89	disease	0,95	disease	0,76	disease	0,84	7	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,28	high_impact	3,52	0,5	0,8	29,02	7,24	P	0,69	P	0,98	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5979	5979	G	T	MI.2039	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	76	26	A	S	Gct/Tct	-0,11	0,56	0	probably_damaging	1	neutral	0,63	neutral	2,71	neutral	-1,2	neutral	-0,42	neutral_impact	-0,2	damaging	0,56	neutral	0,67	neutral	1,68	14,32	0,43	0,55	neutral	0,31	neutral	0,16	neutral	0,2	neutral	0,29	4	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,68	low_impact	-3,58	medium_impact	0,32	low_impact	-1,28	0,8	0,9	2,14	7,08	N	0,35	N	0,64	disease_causing	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12869	12869	G	C	MI.20390	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	533	178	G	A	gGc/gCc	5,92	1	0	probably_damaging	1	neutral	0,6	neutral	4,26	neutral	-2,7	deleterious	-5,93	medium_impact	3,03	damaging	0,45	damaging	0,24	deleterious	3,11	22,5	0,28	0,45	disease	0,73	disease	0,82	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,33	medium_impact	1,57	0,73	0,85	29,02	7,24	P	0,54	P	0,79	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12871	12871	G	C	MI.20391	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	535	179	D	H	Gat/Cat	-9,91	0	0	probably_damaging	1	neutral	0,52	neutral	4,29	deleterious	-4,95	deleterious	-6,92	high_impact	5,13	damaging	0,4	damaging	0,02	deleterious	3,65	23,2	0,41	0,5	disease	0,9	disease	0,93	disease	0,81	disease	0,82	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,25	high_impact	3,48	0,68	0,85	26,7	7,19	P	0,57	P	0,99	polymorphism	0,72	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12871	12871	G	A	MI.20392	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	535	179	D	N	Gat/Aat	-9,91	0	0	probably_damaging	1	neutral	0,33	neutral	4,32	deleterious	-3,37	deleterious	-4,94	high_impact	5,13	damaging	0,33	damaging	0,03	deleterious	4,16	23,8	0,61	0,65	disease	0,83	disease	0,92	disease	0,73	disease	0,77	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,06	high_impact	3,48	0,78	0,85	26,7	7,19	P	0,62	P	0,98	polymorphism	0,93	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12871	12871	G	T	MI.20393	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	535	179	D	Y	Gat/Tat	-9,91	0	0	probably_damaging	1	neutral	1	neutral	4,29	deleterious	-5,86	deleterious	-8,89	high_impact	5,13	damaging	0,38	damaging	0,03	deleterious	3,92	23,5	0,29	0,45	disease	0,92	disease	0,97	disease	0,77	disease	0,83	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,9	low_impact	-3,6	high_impact	1,89	high_impact	3,48	0,57	0,8	26,7	7,19	P	0,53	P	0,99	polymorphism	0,55	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12872	12872	A	C	MI.20394	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	536	179	D	A	gAt/gCt	7,07	1	0	probably_damaging	1	neutral	0,52	neutral	4,39	neutral	-1,85	deleterious	-7,91	high_impact	4,58	damaging	0,38	damaging	0,03	deleterious	3,67	23,3	0,3	0,45	disease	0,75	disease	0,92	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,25	high_impact	2,98	0,62	0,8	26,7	7,19	P	0,67	P	0,94	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12872	12872	A	T	MI.20395	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	536	179	D	V	gAt/gTt	7,07	1	0	probably_damaging	1	neutral	0,52	neutral	4,3	deleterious	-4,58	deleterious	-8,89	high_impact	5,13	damaging	0,35	damaging	0,03	deleterious	3,85	23,4	0,25	0,45	disease	0,81	disease	0,96	disease	0,75	disease	0,83	7	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,25	high_impact	3,48	0,54	0,8	26,7	7,19	P	0,67	P	0,99	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12872	12872	A	G	MI.20396	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	536	179	D	G	gAt/gGt	7,07	1	0	probably_damaging	1	neutral	0,36	neutral	4,31	deleterious	-3,67	deleterious	-6,92	medium_impact	2,7	damaging	0,39	damaging	0,03	deleterious	4,02	23,6	0,36	0,5	disease	0,5	disease	0,93	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,1	medium_impact	1,26	0,56	0,8	26,7	7,19	P	0,56	P	0,98	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12873	12873	T	A	MI.20397	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	537	179	D	E	gaT/gaA	8,44	1	0	probably_damaging	1	neutral	0,29	neutral	4,35	neutral	-2,63	deleterious	-3,95	high_impact	4,58	damaging	0,38	damaging	0,02	deleterious	4,01	23,6	0,5	0,6	disease	0,76	disease	0,91	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,02	high_impact	2,98	0,68	0,85	26,7	7,19	P	0,75	P	0,91	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12873	12873	T	G	MI.20398	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	537	179	D	E	gaT/gaG	8,44	1	0	probably_damaging	1	neutral	0,29	neutral	4,35	neutral	-2,63	deleterious	-3,95	high_impact	4,58	damaging	0,38	damaging	0,02	deleterious	3,89	23,5	0,5	0,6	disease	0,76	disease	0,91	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,02	high_impact	2,98	0,68	0,85	26,7	7,19	P	0,74	P	0,91	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12874	12874	A	T	MI.20399	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	538	180	I	F	Atc/Ttc	-2,8	0	0	probably_damaging	0,97	neutral	0,73	neutral	4,57	neutral	-0,1	deleterious	-3,85	low_impact	1,04	neutral	0,62	neutral	0,41	deleterious	3,6	23,2	0,61	0,65	disease	0,53	disease	0,86	disease	0,66	disease	0,56	1	neutral	0,97	neutral	0,38	neutral	-2	deleterious	0,79	low_impact	-2,18	medium_impact	0,47	medium_impact	-0,25	0,82	0,85	8,96	12,31	N	0,19	N	0,95	disease_causing	0,98	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8621	8621	C	T	MI.204	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	95	32	P	L	cCc/cTc	0,13	0	0	probably_damaging	1	neutral	0,27	neutral	4,47	neutral	1,97	deleterious	-7,74	low_impact	1,3	neutral	0,79	damaging	0,19	deleterious	4,18	23,8	0,42	0,65	disease	0,55	disease	0,84	neutral	0,48	disease	0,66	3	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,77	low_impact	-3,6	medium_impact	0,05	medium_impact	0,02	0,75	0,9	29,2	19,38	N	0,27	N	0,39	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5980	5980	C	A	MI.2040	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	77	26	A	D	gCt/gAt	9,38	1	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-4,23	neutral	-2,06	high_impact	3,75	neutral	0,61	neutral	0,42	deleterious	4,34	24	0,14	0,55	disease	0,63	disease	0,92	disease	0,64	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,36	0,64	0,9	2,14	7,08	P	0,55	P	0,89	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12874	12874	A	C	MI.20400	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	538	180	I	L	Atc/Ctc	-2,8	0	0	possibly_damaging	0,61	neutral	0,86	neutral	4,68	neutral	1,45	neutral	-1,87	neutral_impact	0,69	neutral	0,69	neutral	0,6	deleterious	3,62	23,2	0,42	0,5	neutral	0,36	disease	0,84	disease	0,58	disease	0,52	0	neutral	0,54	deleterious	0,63	neutral	-3	deleterious	0,7	medium_impact	-0,93	medium_impact	0,67	medium_impact	-0,57	0,81	0,85	8,96	12,31	N	0,29	N	0,66	polymorphism	0,66	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12874	12874	A	G	MI.20401	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	538	180	I	V	Atc/Gtc	-2,8	0	0	benign	0,12	neutral	0,63	neutral	4,64	neutral	0,71	neutral	-0,57	neutral_impact	0,4	neutral	0,85	neutral	0,98	neutral	1,68	14,27	0,71	0,75	neutral	0,39	neutral	0,46	neutral	0,44	neutral	0,43	1	neutral	0,27	deleterious	0,76	neutral	-6	deleterious	0,65	medium_impact	0,08	medium_impact	0,36	medium_impact	-0,84	0,71	0,85	8,96	12,31	N	0,29	N	0,25	polymorphism	0,82	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12875	12875	T	C	MI.20402	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	539	180	I	T	aTc/aCc	1,33	0,52	0	probably_damaging	0,91	neutral	0,62	neutral	4,53	neutral	-1,27	deleterious	-4,45	low_impact	1,88	neutral	0,64	neutral	0,52	deleterious	3,36	22,9	0,59	0,65	disease	0,69	disease	0,83	disease	0,64	disease	0,63	3	neutral	0,9	neutral	0,36	neutral	-2	deleterious	0,79	low_impact	-1,7	medium_impact	0,35	medium_impact	0,51	0,66	0,8	8,96	12,31	N	0,23	N	0,96	disease_causing	0,77	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12875	12875	T	G	MI.20403	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	539	180	I	S	aTc/aGc	1,33	0,52	0	probably_damaging	0,96	neutral	0,68	neutral	4,54	neutral	-1,39	deleterious	-5,6	low_impact	1,77	neutral	0,7	neutral	0,47	deleterious	4,22	23,9	0,45	0,55	disease	0,61	disease	0,91	disease	0,67	disease	0,74	5	neutral	0,95	neutral	0,36	neutral	-2	deleterious	0,82	low_impact	-2,06	medium_impact	0,41	medium_impact	0,41	0,55	0,8	8,96	12,31	N	0,22	N	0,96	disease_causing	0,93	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12875	12875	T	A	MI.20404	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	539	180	I	N	aTc/aAc	1,33	0,52	0	probably_damaging	0,98	neutral	0,58	neutral	4,45	deleterious	-3,18	deleterious	-6,59	high_impact	3,64	damaging	0,59	neutral	0,41	deleterious	4,32	24	0,41	0,5	disease	0,8	disease	0,94	disease	0,67	disease	0,78	6	deleterious	0,98	neutral	0,3	deleterious	2	deleterious	0,84	low_impact	-2,35	medium_impact	0,31	high_impact	2,12	0,56	0,8	8,96	12,31	N	0,31	N	0,98	disease_causing	0,91	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12876	12876	C	A	MI.20405	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	540	180	I	M	atC/atA	5,69	0,93	0	probably_damaging	0,97	neutral	0,29	neutral	4,47	neutral	-1,31	deleterious	-2,54	low_impact	1,82	neutral	0,79	neutral	0,91	deleterious	3,76	23,3	0,61	0,65	disease	0,75	disease	0,77	disease	0,55	disease	0,56	1	neutral	0,97	neutral	0,16	neutral	-2	deleterious	0,76	low_impact	-2,18	medium_impact	0,02	medium_impact	0,46	0,82	0,85	8,96	12,31	N	0,42	N	0,76	disease_causing	0,9	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12876	12876	C	G	MI.20406	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	540	180	I	M	atC/atG	5,69	0,93	0	probably_damaging	0,97	neutral	0,29	neutral	4,47	neutral	-1,31	deleterious	-2,54	low_impact	1,82	neutral	0,79	neutral	0,91	deleterious	3,25	22,8	0,61	0,65	disease	0,75	disease	0,77	disease	0,55	disease	0,56	1	neutral	0,97	neutral	0,16	neutral	-2	deleterious	0,76	low_impact	-2,18	medium_impact	0,02	medium_impact	0,46	0,82	0,85	8,96	12,31	N	0,42	N	0,76	disease_causing	0,9	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12877	12877	G	A	MI.20407	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	541	181	G	S	Ggt/Agt	-3,94	0	0	probably_damaging	1	neutral	0,43	neutral	4,6	neutral	-2,56	deleterious	-5,93	medium_impact	3,36	damaging	0,38	damaging	0,03	deleterious	4,11	23,7	0,42	0,55	disease	0,76	disease	0,9	disease	0,62	disease	0,69	4	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	0,17	medium_impact	1,87	0,73	0,85	27,69	7,23	N	0,45	N	1	disease_causing	0,95	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12877	12877	G	C	MI.20408	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	541	181	G	R	Ggt/Cgt	-3,94	0	0	probably_damaging	1	neutral	0,37	neutral	4,58	deleterious	-5,09	deleterious	-7,91	high_impact	4,71	damaging	0,42	damaging	0,03	deleterious	3,87	23,5	0,14	0,4	disease	0,88	disease	0,96	disease	0,75	disease	0,83	7	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	0,11	high_impact	3,1	0,6	0,8	27,69	7,23	P	0,55	P	1	disease_causing	0,98	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12877	12877	G	T	MI.20409	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	541	181	G	C	Ggt/Tgt	-3,94	0	0	probably_damaging	1	neutral	0,18	neutral	4,57	deleterious	-4,03	deleterious	-8,89	medium_impact	2,78	damaging	0,37	damaging	0,02	deleterious	4,08	23,7	0,24	0,45	disease	0,84	disease	0,94	disease	0,66	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,88	low_impact	-3,6	medium_impact	-0,13	medium_impact	1,34	0,55	0,8	27,69	7,23	N	0,46	N	0,97	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5980	5980	C	T	MI.2041	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	77	26	A	V	gCt/gTt	9,38	1	0	probably_damaging	1	deleterious	0	neutral	2,75	neutral	-0,55	neutral	-1,75	medium_impact	3,06	damaging	0,55	neutral	0,41	deleterious	4,16	23,8	0,38	0,55	neutral	0,4	disease	0,76	disease	0,51	disease	0,61	2	deleterious	1	neutral	0	deleterious	5	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	medium_impact	1,73	0,76	0,9	2,14	7,08	P	0,56	P	0,75	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12878	12878	G	A	MI.20410	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	542	181	G	D	gGt/gAt	9,13	1	0	probably_damaging	1	neutral	0,23	neutral	4,57	deleterious	-6,27	deleterious	-6,92	high_impact	4,71	damaging	0,36	damaging	0,02	deleterious	3,7	23,3	0,2	0,45	disease	0,94	disease	0,94	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,06	high_impact	3,1	0,44	0,8	27,69	7,23	P	0,72	P	0,95	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12878	12878	G	T	MI.20411	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	542	181	G	V	gGt/gTt	9,13	1	0	probably_damaging	1	neutral	0,51	neutral	4,69	neutral	-1,75	deleterious	-8,89	medium_impact	3,29	damaging	0,34	damaging	0,03	deleterious	3,78	23,4	0,34	0,5	neutral	0,5	disease	0,95	disease	0,63	disease	0,77	5	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,24	medium_impact	1,8	0,54	0,8	27,69	7,23	P	0,59	P	0,98	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12878	12878	G	C	MI.20412	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	542	181	G	A	gGt/gCt	9,13	1	0	probably_damaging	1	neutral	0,54	neutral	4,64	neutral	-1,1	deleterious	-5,93	medium_impact	2,24	damaging	0,38	damaging	0,05	deleterious	3,18	22,7	0,55	0,6	disease	0,53	disease	0,84	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,27	medium_impact	0,84	0,71	0,85	27,69	7,23	P	0,58	P	0,79	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12880	12880	T	A	MI.20413	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	544	182	F	I	Ttc/Atc	-10,14	0	0,06	possibly_damaging	0,81	neutral	0,55	neutral	4,69	neutral	0,38	deleterious	-4,65	neutral_impact	0,66	neutral	0,75	neutral	0,73	deleterious	4,4	24,1	0,3	0,45	neutral	0,42	disease	0,85	disease	0,51	disease	0,54	1	neutral	0,79	neutral	0,37	neutral	-3	deleterious	0,76	low_impact	-1,34	medium_impact	0,28	medium_impact	-0,6	0,63	0,8	4,48	9,53	N	0,28	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12880	12880	T	G	MI.20414	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	544	182	F	V	Ttc/Gtc	-10,14	0	0,06	possibly_damaging	0,81	neutral	0,67	neutral	4,58	neutral	-0,82	deleterious	-5,64	medium_impact	2,63	neutral	0,73	neutral	0,53	deleterious	4,1	23,7	0,3	0,45	disease	0,64	disease	0,9	disease	0,6	disease	0,72	4	neutral	0,78	neutral	0,43	NA	0	deleterious	0,8	low_impact	-1,34	medium_impact	0,4	medium_impact	1,2	0,64	0,8	4,48	9,53	N	0,23	N	0,93	polymorphism	1	0,08	rs28719001	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12880	12880	T	C	MI.20415	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	544	182	F	L	Ttc/Ctc	-10,14	0	0,06	benign	0,12	neutral	0,84	neutral	5,52	neutral	3,15	deleterious	-4,33	neutral_impact	-0,66	neutral	0,81	neutral	0,88	neutral	1,36	12,57	0,49	0,55	neutral	0,49	neutral	0,29	neutral	0,32	neutral	0,41	2	neutral	0,07	deleterious	0,86	neutral	-6	deleterious	0,68	medium_impact	0,08	medium_impact	0,63	low_impact	-1,81	0,64	0,8	4,48	9,53	N	0,32	N	0,48	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12881	12881	T	A	MI.20416	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	545	182	F	Y	tTc/tAc	-0,04	0	0	probably_damaging	0,92	neutral	1	neutral	4,49	deleterious	-4,09	deleterious	-2,64	high_impact	3,56	neutral	0,68	neutral	0,46	deleterious	4,15	23,8	0,24	0,45	disease	0,75	disease	0,84	disease	0,6	disease	0,75	5	neutral	0,92	deleterious	0,54	deleterious	2	deleterious	0,82	low_impact	-1,75	high_impact	1,89	high_impact	2,05	0,71	0,85	4,48	9,53	N	0,23	N	0,71	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12881	12881	T	G	MI.20417	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	545	182	F	C	tTc/tGc	-0,04	0	0	probably_damaging	0,99	neutral	0,2	neutral	4,49	deleterious	-4,86	deleterious	-6,79	high_impact	3,91	neutral	0,66	neutral	0,45	deleterious	4,06	23,7	0,24	0,45	disease	0,91	disease	0,91	disease	0,62	disease	0,81	6	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-2,64	medium_impact	-0,1	high_impact	2,37	0,46	0,8	4,48	9,53	N	0,36	N	0,96	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12881	12881	T	C	MI.20418	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	545	182	F	S	tTc/tCc	-0,04	0	0	probably_damaging	0,97	neutral	0,56	neutral	4,49	deleterious	-4,21	deleterious	-6,95	medium_impact	3,36	neutral	0,68	neutral	0,48	deleterious	4,22	23,9	0,24	0,45	disease	0,79	disease	0,86	disease	0,6	disease	0,76	5	neutral	0,97	neutral	0,3	deleterious	1	deleterious	0,83	low_impact	-2,18	medium_impact	0,29	medium_impact	1,87	0,5	0,8	4,48	9,53	N	0,28	N	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12882	12882	C	A	MI.20419	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	546	182	F	L	ttC/ttA	7,3	0,95	0,12	benign	0,12	neutral	0,84	neutral	5,52	neutral	3,15	deleterious	-4,33	neutral_impact	-0,66	neutral	0,81	neutral	0,88	deleterious	1,93	15,78	0,49	0,55	neutral	0,49	neutral	0,29	neutral	0,32	neutral	0,41	2	neutral	0,07	deleterious	0,86	neutral	-6	deleterious	0,68	medium_impact	0,08	medium_impact	0,63	low_impact	-1,81	0,64	0,8	4,48	9,53	N	0,45	N	0,48	polymorphism	1	0,07	rs386420001	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5980	5980	C	G	MI.2042	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	77	26	A	G	gCt/gGt	9,38	1	0	probably_damaging	0,99	deleterious	0,01	neutral	2,66	neutral	-2,59	neutral	-1,44	medium_impact	2,46	damaging	0,59	neutral	0,54	deleterious	3,74	23,3	0,29	0,55	neutral	0,46	disease	0,68	neutral	0,3	disease	0,52	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,72	low_impact	-2,64	medium_impact	-0,92	medium_impact	1,17	0,76	0,9	2,14	7,08	P	0,55	P	0,56	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12882	12882	C	G	MI.20420	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	546	182	F	L	ttC/ttG	7,3	0,95	0,12	benign	0,12	neutral	0,84	neutral	5,52	neutral	3,15	deleterious	-4,33	neutral_impact	-0,66	neutral	0,81	neutral	0,88	neutral	1,6	13,84	0,49	0,55	neutral	0,49	neutral	0,29	neutral	0,32	neutral	0,41	2	neutral	0,07	deleterious	0,86	neutral	-6	deleterious	0,68	medium_impact	0,08	medium_impact	0,63	low_impact	-1,81	0,64	0,8	4,48	9,53	N	0,45	N	0,48	polymorphism	1	0,07	rs386420001	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12883	12883	A	G	MI.20421	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	547	183	I	V	Atc/Gtc	-9,91	0	0	benign	0,05	neutral	0,5	neutral	4,6	neutral	-0,59	neutral	-0,5	low_impact	1,45	neutral	0,89	neutral	0,96	deleterious	-0,04	2,22	0,48	0,55	neutral	0,5	disease	0,51	neutral	0,35	neutral	0,44	1	neutral	0,45	deleterious	0,73	neutral	-6	neutral	0,17	medium_impact	0,47	medium_impact	0,23	medium_impact	0,12	0,59	0,8	18,57	15,73	N	0,27	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12883	12883	A	T	MI.20422	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	547	183	I	F	Atc/Ttc	-9,91	0	0	probably_damaging	0,93	neutral	0,7	neutral	4,65	neutral	0,06	deleterious	-3,86	low_impact	1,82	neutral	0,77	neutral	0,53	deleterious	3,49	23,1	0,33	0,5	disease	0,6	disease	0,89	neutral	0,49	disease	0,66	3	neutral	0,92	neutral	0,39	neutral	-2	deleterious	0,71	low_impact	-1,81	medium_impact	0,44	medium_impact	0,46	0,73	0,85	18,57	15,73	N	0,17	N	0,72	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12883	12883	A	C	MI.20423	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	547	183	I	L	Atc/Ctc	-9,91	0	0	benign	0,39	neutral	0,65	neutral	5,7	neutral	3,69	neutral	-1,81	neutral_impact	-0,54	neutral	0,81	neutral	0,93	deleterious	0,8	9,47	0,28	0,45	disease	0,59	disease	0,65	neutral	0,41	neutral	0,48	0	neutral	0,32	deleterious	0,63	neutral	-6	neutral	0,21	medium_impact	-0,56	medium_impact	0,38	low_impact	-1,7	0,58	0,8	18,57	15,73	N	0,29	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12884	12884	T	A	MI.20424	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	548	183	I	N	aTc/aAc	-0,27	0	0	probably_damaging	0,96	neutral	0,31	neutral	4,51	deleterious	-4,57	deleterious	-6,58	high_impact	3,94	neutral	0,69	neutral	0,42	deleterious	4,37	24,1	0,23	0,45	disease	0,9	disease	0,92	disease	0,57	disease	0,78	6	neutral	0,97	neutral	0,18	deleterious	2	deleterious	0,81	low_impact	-2,06	medium_impact	0,04	high_impact	2,4	0,55	0,8	18,57	15,73	N	0,38	N	0,87	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12884	12884	T	G	MI.20425	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	548	183	I	S	aTc/aGc	-0,27	0	0	probably_damaging	0,9	neutral	0,4	neutral	4,52	deleterious	-3,4	deleterious	-5,59	medium_impact	2,8	neutral	0,68	neutral	0,47	deleterious	3,96	23,6	0,24	0,45	disease	0,72	disease	0,89	disease	0,58	disease	0,65	3	neutral	0,9	neutral	0,25	deleterious	1	deleterious	0,64	low_impact	-1,65	medium_impact	0,14	medium_impact	1,36	0,47	0,8	18,57	15,73	N	0,27	N	0,78	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12884	12884	T	C	MI.20426	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	548	183	I	T	aTc/aCc	-0,27	0	0	possibly_damaging	0,75	neutral	0,39	neutral	4,53	neutral	-2,74	deleterious	-4,36	medium_impact	3,05	neutral	0,73	neutral	0,45	neutral	1,75	14,68	0,44	0,55	disease	0,68	disease	0,82	disease	0,58	disease	0,68	4	neutral	0,77	neutral	0,32	NA	0	deleterious	0,54	low_impact	-1,2	medium_impact	0,13	medium_impact	1,58	0,54	0,8	18,57	15,73	N	0,28	N	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12885	12885	C	A	MI.20427	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	549	183	I	M	atC/atA	5,69	0,86	0	probably_damaging	0,93	neutral	0,22	neutral	4,62	neutral	-0,26	deleterious	-2,57	low_impact	1,6	neutral	0,78	neutral	0,9	deleterious	2,53	19,64	0,38	0,5	disease	0,58	disease	0,68	neutral	0,32	neutral	0,49	0	neutral	0,95	neutral	0,15	neutral	-2	deleterious	0,64	low_impact	-1,81	medium_impact	-0,07	medium_impact	0,26	0,74	0,85	18,57	15,73	N	0,39	N	0,23	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12885	12885	C	G	MI.20428	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	549	183	I	M	atC/atG	5,69	0,86	0	probably_damaging	0,93	neutral	0,22	neutral	4,62	neutral	-0,26	deleterious	-2,57	low_impact	1,6	neutral	0,78	neutral	0,9	deleterious	2,05	16,54	0,38	0,5	disease	0,58	disease	0,68	neutral	0,32	neutral	0,49	0	neutral	0,95	neutral	0,15	neutral	-2	deleterious	0,64	low_impact	-1,81	medium_impact	-0,07	medium_impact	0,26	0,74	0,85	18,57	15,73	N	0,39	N	0,23	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12886	12886	C	G	MI.20429	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	550	184	L	V	Ctc/Gtc	-3,94	0	0	probably_damaging	0,94	neutral	0,58	neutral	4,51	neutral	-1,69	neutral	-2,12	low_impact	1,19	neutral	0,79	neutral	0,66	deleterious	3,33	22,9	0,33	0,5	disease	0,68	disease	0,72	neutral	0,44	disease	0,54	1	neutral	0,94	neutral	0,32	neutral	-2	deleterious	0,76	low_impact	-1,88	medium_impact	0,31	medium_impact	-0,12	0,54	0,8	7,63	12,53	N	0,19	N	0,63	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5982	5982	G	C	MI.2043	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	79	27	G	R	Gga/Cga	-9,82	0	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,45	deleterious	-3,48	high_impact	4,4	damaging	0,59	damaging	0,03	deleterious	3,81	23,4	0,12	0,55	disease	0,61	disease	0,92	disease	0,72	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,96	0,75	0,9	4,68	7,56	N	0,4	N	0,95	polymorphism	0,72	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12886	12886	C	T	MI.20430	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	550	184	L	F	Ctc/Ttc	-3,94	0	0	probably_damaging	0,99	neutral	0,78	neutral	4,6	neutral	-2,33	deleterious	-3,36	low_impact	1,82	neutral	0,73	neutral	0,41	deleterious	2,78	21,3	0,34	0,5	disease	0,61	disease	0,64	neutral	0,32	neutral	0,49	0	deleterious	0,99	neutral	0,4	neutral	-2	deleterious	0,76	low_impact	-2,64	medium_impact	0,54	medium_impact	0,46	0,58	0,8	7,63	12,53	N	0,19	N	0,84	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12886	12886	C	A	MI.20431	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	550	184	L	I	Ctc/Atc	-3,94	0	0	probably_damaging	0,96	neutral	0,6	neutral	4,49	neutral	-1,44	neutral	-1,4	neutral_impact	0,78	neutral	0,77	neutral	0,54	deleterious	3,99	23,6	0,33	0,5	disease	0,54	disease	0,68	neutral	0,29	neutral	0,5	0	neutral	0,95	neutral	0,32	neutral	-2	deleterious	0,75	low_impact	-2,06	medium_impact	0,33	medium_impact	-0,49	0,77	0,85	7,63	12,53	N	0,2	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12887	12887	T	A	MI.20432	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	551	184	L	H	cTc/cAc	-5,09	0	0	probably_damaging	1	neutral	0,54	neutral	4,36	deleterious	-5,93	deleterious	-6,02	high_impact	4,25	neutral	0,73	damaging	0,13	deleterious	4,14	23,8	0,16	0,45	disease	0,9	disease	0,88	disease	0,64	disease	0,79	6	deleterious	0,99	neutral	0,27	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,27	high_impact	2,68	0,67	0,85	7,63	12,53	N	0,3	N	0,86	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12887	12887	T	C	MI.20433	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	551	184	L	P	cTc/cCc	-5,09	0	0	probably_damaging	0,99	neutral	0,22	neutral	4,36	deleterious	-5,37	deleterious	-5,95	high_impact	3,7	neutral	0,64	damaging	0,12	deleterious	3,89	23,5	0,2	0,45	disease	0,92	disease	0,93	disease	0,67	disease	0,82	6	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,9	low_impact	-2,64	medium_impact	-0,07	high_impact	2,18	0,68	0,85	7,63	12,53	N	0,27	N	0,91	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12887	12887	T	G	MI.20434	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	551	184	L	R	cTc/cGc	-5,09	0	0	probably_damaging	0,98	neutral	0,34	neutral	4,37	deleterious	-5,75	deleterious	-5,12	high_impact	4,25	neutral	0,68	damaging	0,11	deleterious	4,18	23,8	0,13	0,4	disease	0,93	disease	0,94	disease	0,68	disease	0,82	6	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-2,35	medium_impact	0,07	high_impact	2,68	0,58	0,8	7,63	12,53	N	0,34	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12889	12889	G	T	MI.20435	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	553	185	A	S	Gcc/Tcc	-2,34	0	0	possibly_damaging	0,86	neutral	0,61	neutral	4,51	neutral	-2,65	neutral	0,28	neutral_impact	0,64	neutral	0,84	neutral	0,98	deleterious	0,88	9,95	0,3	0,45	disease	0,58	neutral	0,3	neutral	0,25	disease	0,61	2	neutral	0,83	neutral	0,38	neutral	-3	deleterious	0,47	low_impact	-1,5	medium_impact	0,34	medium_impact	-0,62	0,77	0,85	11,61	11,79	N	0,35	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12889	12889	G	A	MI.20436	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	553	185	A	T	Gcc/Acc	-2,34	0	0	benign	0,15	neutral	0,41	neutral	4,45	deleterious	-3,66	neutral	-0,97	low_impact	1,81	neutral	0,88	neutral	0,97	deleterious	0,57	7,97	0,29	0,45	disease	0,52	neutral	0,47	neutral	0,29	neutral	0,47	1	neutral	0,51	deleterious	0,63	neutral	-6	neutral	0,2	medium_impact	-0,03	medium_impact	0,15	medium_impact	0,45	0,69	0,85	11,61	11,79	N	0,43	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12889	12889	G	C	MI.20437	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	553	185	A	P	Gcc/Ccc	-2,34	0	0	probably_damaging	0,98	neutral	0,16	neutral	4,4	deleterious	-5,55	deleterious	-2,99	high_impact	4	neutral	0,67	neutral	0,31	deleterious	3,71	23,3	0,15	0,4	disease	0,93	disease	0,94	disease	0,67	disease	0,83	7	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-2,35	medium_impact	-0,17	high_impact	2,45	0,7	0,85	11,61	11,79	N	0,35	N	0,9	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12890	12890	C	T	MI.20438	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	554	185	A	V	gCc/gTc	-2,11	0	0	possibly_damaging	0,86	neutral	0,5	neutral	4,5	neutral	-2,65	deleterious	-2,82	medium_impact	2,25	neutral	0,83	neutral	0,64	deleterious	4,09	23,7	0,35	0,5	disease	0,66	disease	0,82	disease	0,55	disease	0,68	4	neutral	0,84	neutral	0,32	NA	0	deleterious	0,6	low_impact	-1,5	medium_impact	0,23	medium_impact	0,85	0,61	0,8	11,61	11,79	N	0,24	N	0,48	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12890	12890	C	A	MI.20439	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	554	185	A	D	gCc/gAc	-2,11	0	0	probably_damaging	0,98	neutral	0,13	neutral	4,41	deleterious	-6,3	deleterious	-2,97	high_impact	4	neutral	0,73	neutral	0,37	deleterious	4,45	24,2	0,14	0,4	disease	0,94	disease	0,92	disease	0,67	disease	0,84	7	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-2,35	medium_impact	-0,22	high_impact	2,45	0,58	0,8	11,61	11,79	N	0,37	N	0,97	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5982	5982	G	T	MI.2044	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	79	27	G	W	Gga/Tga	-9,82	0	0	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-3,72	deleterious	-3,62	high_impact	4,4	damaging	0,55	damaging	0,03	deleterious	4,27	23,9	0,18	0,55	disease	0,82	disease	0,93	disease	0,65	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,96	0,46	0,9	4,68	7,56	N	0,36	N	0,83	polymorphism	0,61	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12890	12890	C	G	MI.20440	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	554	185	A	G	gCc/gGc	-2,11	0	0	possibly_damaging	0,89	neutral	0,34	neutral	4,66	neutral	0,47	neutral	-2,31	neutral_impact	0,76	neutral	0,73	neutral	0,66	deleterious	3,61	23,2	0,31	0,45	neutral	0,43	disease	0,63	disease	0,51	neutral	0,46	1	neutral	0,9	neutral	0,23	neutral	-3	deleterious	0,51	low_impact	-1,61	medium_impact	0,07	medium_impact	-0,51	0,74	0,85	11,61	11,79	N	0,29	N	0,52	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12892	12892	T	G	MI.20441	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	556	186	L	V	Tta/Gta	-8,53	0	0,01	possibly_damaging	0,62	neutral	0,58	neutral	4,63	neutral	-1,25	neutral	-1,07	low_impact	1,22	neutral	0,72	neutral	0,75	deleterious	3,36	22,9	0,42	0,55	disease	0,55	disease	0,68	neutral	0,45	disease	0,51	0	neutral	0,57	deleterious	0,48	neutral	-3	deleterious	0,73	medium_impact	-0,95	medium_impact	0,31	medium_impact	-0,09	0,66	0,8	5,64	10,67	N	0,26	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12892	12892	T	A	MI.20442	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	556	186	L	M	Tta/Ata	-8,53	0	0,01	benign	0,21	neutral	0,35	neutral	4,59	neutral	-1,31	neutral	2,75	neutral_impact	0,23	neutral	0,79	neutral	0,94	deleterious	0,85	9,76	0,33	0,5	neutral	0,46	neutral	0,04	neutral	0,21	neutral	0,25	5	neutral	0,58	deleterious	0,57	neutral	-6	deleterious	0,66	medium_impact	-0,2	medium_impact	0,08	medium_impact	-0,99	0,71	0,85	5,64	10,67	N	0,41	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12893	12893	T	C	MI.20443	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	557	186	L	S	tTa/tCa	2,94	0,98	0	possibly_damaging	0,9	neutral	0,5	neutral	4,53	deleterious	-3,87	deleterious	-3,09	medium_impact	2,65	neutral	0,69	neutral	0,66	deleterious	3,7	23,3	0,3	0,45	disease	0,7	disease	0,73	disease	0,56	disease	0,7	4	neutral	0,89	neutral	0,3	NA	0	deleterious	0,79	low_impact	-1,65	medium_impact	0,23	medium_impact	1,22	0,73	0,85	5,64	10,67	N	0,46	N	0,64	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12893	12893	T	G	MI.20444	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	557	186	L	W	tTa/tGa	2,94	0,98	0	probably_damaging	0,98	neutral	0,28	neutral	4,47	deleterious	-6,26	deleterious	-3,1	high_impact	3,89	neutral	0,67	neutral	0,48	deleterious	3,71	23,3	0,14	0,4	disease	0,95	disease	0,85	disease	0,59	disease	0,86	7	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-2,35	medium_impact	0,01	high_impact	2,35	0,52	0,8	5,64	10,67	P	0,52	P	0,7	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12894	12894	A	C	MI.20445	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	558	186	L	F	ttA/ttC	7,3	1	0	possibly_damaging	0,87	neutral	0,74	neutral	4,59	neutral	-1,8	neutral	-2,06	low_impact	0,9	neutral	0,7	neutral	0,83	deleterious	3,45	23	0,4	0,5	neutral	0,47	disease	0,77	disease	0,54	disease	0,54	1	neutral	0,84	neutral	0,44	neutral	-3	deleterious	0,75	low_impact	-1,53	medium_impact	0,48	medium_impact	-0,38	0,64	0,8	5,64	10,67	N	0,48	N	0,32	polymorphism	0,52	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12894	12894	A	T	MI.20446	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	558	186	L	F	ttA/ttT	7,3	1	0	possibly_damaging	0,87	neutral	0,74	neutral	4,59	neutral	-1,8	neutral	-2,06	low_impact	0,9	neutral	0,7	neutral	0,83	deleterious	3,55	23,1	0,4	0,5	neutral	0,47	disease	0,77	disease	0,54	disease	0,54	1	neutral	0,84	neutral	0,44	neutral	-3	deleterious	0,75	low_impact	-1,53	medium_impact	0,48	medium_impact	-0,38	0,64	0,8	5,64	10,67	N	0,48	N	0,32	polymorphism	0,52	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12895	12895	G	C	MI.20447	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	559	187	A	P	Gca/Cca	1,56	0,9	0	probably_damaging	0,95	neutral	0,3	neutral	4,54	deleterious	-4,86	deleterious	-4,2	medium_impact	2,95	neutral	0,66	neutral	0,29	deleterious	3,75	23,3	0,17	0,45	disease	0,94	disease	0,93	disease	0,72	disease	0,84	7	neutral	0,96	neutral	0,18	deleterious	1	deleterious	0,85	low_impact	-1,96	medium_impact	0,03	medium_impact	1,49	0,86	0,9	10,61	10,41	N	0,33	N	0,95	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12895	12895	G	A	MI.20448	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	559	187	A	T	Gca/Aca	1,56	0,9	0	benign	0,09	neutral	0,59	neutral	4,58	neutral	-2,57	deleterious	-2,52	low_impact	1,32	neutral	0,79	neutral	0,71	neutral	1,1	11,24	0,54	0,6	disease	0,79	disease	0,77	neutral	0,42	disease	0,63	3	neutral	0,32	deleterious	0,75	neutral	-6	neutral	0,28	medium_impact	0,21	medium_impact	0,32	medium_impact	0	0,69	0,85	10,61	10,41	N	0,23	N	0,54	disease_causing	1	0,06	.	.	.	.	.	.	COSM1636857	.	.	.	.	.	.	.	.
chrM	12895	12895	G	T	MI.20449	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	559	187	A	S	Gca/Tca	1,56	0,9	0	possibly_damaging	0,64	neutral	0,84	neutral	4,76	neutral	-1,73	neutral	-2,35	neutral_impact	0,49	neutral	0,67	neutral	0,65	deleterious	3,26	22,8	0,5	0,6	neutral	0,5	disease	0,75	neutral	0,42	disease	0,52	0	neutral	0,58	deleterious	0,6	neutral	-3	deleterious	0,54	medium_impact	-0,98	medium_impact	0,63	medium_impact	-0,76	0,88	0,9	10,61	10,41	N	0,26	N	0,52	disease_causing	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5983	5983	G	T	MI.2045	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	80	27	G	V	gGa/gTa	9,38	1	0	probably_damaging	1	deleterious	0	neutral	2,81	neutral	0,07	deleterious	-3,88	high_impact	4,4	damaging	0,59	damaging	0,03	deleterious	3,58	23,2	0,18	0,55	neutral	0,39	disease	0,87	disease	0,61	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,96	0,56	0,9	4,68	7,56	N	0,45	N	0,93	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12896	12896	C	T	MI.20450	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	560	187	A	V	gCa/gTa	0,41	0,49	0	benign	0,13	neutral	0,59	neutral	4,65	neutral	-0,96	deleterious	-2,88	neutral_impact	0,48	neutral	0,84	neutral	0,65	deleterious	3,91	23,5	0,59	0,65	disease	0,58	disease	0,82	neutral	0,44	disease	0,54	1	neutral	0,31	deleterious	0,73	neutral	-6	deleterious	0,58	medium_impact	0,04	medium_impact	0,32	medium_impact	-0,76	0,72	0,85	10,61	10,41	N	0,22	N	0,46	disease_causing	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12896	12896	C	G	MI.20451	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	560	187	A	G	gCa/gGa	0,41	0,49	0	possibly_damaging	0,72	neutral	0,46	neutral	4,56	neutral	-1,04	deleterious	-3,61	low_impact	1,18	neutral	0,71	neutral	0,51	deleterious	3,54	23,1	0,44	0,55	disease	0,65	disease	0,77	disease	0,59	disease	0,57	1	neutral	0,71	neutral	0,37	neutral	-3	deleterious	0,59	low_impact	-1,14	medium_impact	0,19	medium_impact	-0,13	0,8	0,85	10,61	10,41	N	0,23	N	0,65	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12896	12896	C	A	MI.20452	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	560	187	A	E	gCa/gAa	0,41	0,49	0	possibly_damaging	0,82	neutral	0,58	neutral	4,54	deleterious	-5,01	deleterious	-4,2	high_impact	3,64	neutral	0,73	neutral	0,39	deleterious	4,34	24	0,16	0,45	disease	0,92	disease	0,92	disease	0,71	disease	0,83	7	neutral	0,79	neutral	0,38	deleterious	1	deleterious	0,77	low_impact	-1,37	medium_impact	0,31	high_impact	2,12	0,75	0,85	10,61	10,41	N	0,31	N	0,91	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12898	12898	T	G	MI.20453	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	562	188	W	G	Tga/Gga	-4,4	0	0	probably_damaging	0,95	neutral	0,35	neutral	4,64	neutral	0,27	deleterious	-12,85	low_impact	1,9	neutral	0,69	neutral	0,42	deleterious	3,87	23,5	0,49	0,55	neutral	0,4	disease	0,87	disease	0,75	disease	0,67	3	neutral	0,96	neutral	0,2	neutral	-2	deleterious	0,74	low_impact	-1,96	medium_impact	0,08	medium_impact	0,53	0,37	0,8	3,48	7,41	N	0,4	N	0,97	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12898	12898	T	C	MI.20454	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	562	188	W	R	Tga/Cga	-4,4	0	0	probably_damaging	0,98	neutral	0,36	neutral	4,57	neutral	-2,35	deleterious	-13,84	high_impact	4	neutral	0,66	damaging	0,26	deleterious	3,49	23,1	0,46	0,55	disease	0,89	disease	0,94	disease	0,78	disease	0,89	8	neutral	0,98	neutral	0,19	deleterious	2	deleterious	0,87	low_impact	-2,35	medium_impact	0,1	high_impact	2,45	0,2	0,8	3,48	7,41	N	0,47	N	0,97	disease_causing	0,98	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12899	12899	G	T	MI.20455	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	563	188	W	L	tGa/tTa	5,69	1	0	possibly_damaging	0,88	neutral	0,68	neutral	4,78	neutral	1,94	deleterious	-12,85	neutral_impact	0,36	neutral	0,69	neutral	0,44	deleterious	4,19	23,8	0,44	0,55	neutral	0,39	disease	0,88	disease	0,74	disease	0,65	3	neutral	0,86	neutral	0,4	neutral	-3	deleterious	0,76	low_impact	-1,57	medium_impact	0,41	medium_impact	-0,87	0,23	0,8	3,48	7,41	N	0,44	N	0,97	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12899	12899	G	C	MI.20456	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	563	188	W	S	tGa/tCa	5,69	1	0	probably_damaging	0,97	neutral	0,44	neutral	4,61	neutral	-1,21	deleterious	-13,84	medium_impact	2,25	neutral	0,72	neutral	0,4	deleterious	3,96	23,6	0,37	0,5	disease	0,65	disease	0,92	disease	0,74	disease	0,8	6	neutral	0,97	neutral	0,24	deleterious	1	deleterious	0,83	low_impact	-2,18	medium_impact	0,18	medium_impact	0,85	0,26	0,8	3,48	7,41	N	0,46	N	0,95	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12900	12900	A	C	MI.20457	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	564	188	W	C	tgA/tgC	5,92	1	0	probably_damaging	0,99	neutral	0,18	neutral	4,56	neutral	-2,29	deleterious	-12,85	medium_impact	2,96	neutral	0,69	neutral	0,37	deleterious	3,98	23,6	0,33	0,5	disease	0,91	disease	0,92	disease	0,75	disease	0,81	6	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,84	low_impact	-2,64	medium_impact	-0,13	medium_impact	1,5	0,21	0,8	3,48	7,41	N	0,46	N	0,98	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12900	12900	A	T	MI.20458	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	564	188	W	C	tgA/tgT	5,92	1	0	probably_damaging	0,99	neutral	0,18	neutral	4,56	neutral	-2,29	deleterious	-12,85	medium_impact	2,96	neutral	0,69	neutral	0,37	deleterious	4,03	23,6	0,33	0,5	disease	0,91	disease	0,92	disease	0,75	disease	0,81	6	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,84	low_impact	-2,64	medium_impact	-0,13	medium_impact	1,5	0,21	0,8	3,48	7,41	N	0,47	N	0,98	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12901	12901	T	A	MI.20459	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	565	189	F	I	Ttt/Att	0,64	0,61	0	possibly_damaging	0,52	neutral	0,44	neutral	4,84	neutral	-0,28	deleterious	-5,56	neutral_impact	-0,02	neutral	0,78	neutral	0,7	neutral	1,39	12,73	0,35	0,5	neutral	0,4	disease	0,61	neutral	0,35	neutral	0,48	0	neutral	0,56	neutral	0,46	neutral	-3	neutral	0,35	medium_impact	-0,78	medium_impact	0,18	low_impact	-1,22	0,63	0,8	16,25	15,98	N	0,25	N	0,91	polymorphism	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5983	5983	G	C	MI.2046	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	80	27	G	A	gGa/gCa	9,38	1	0	probably_damaging	1	neutral	0,05	neutral	2,77	neutral	-0,56	neutral	-2,37	low_impact	1,55	damaging	0,46	damaging	0,1	neutral	1,7	14,41	0,41	0,55	neutral	0,41	disease	0,54	neutral	0,36	neutral	0,46	1	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,75	low_impact	-3,58	medium_impact	-0,52	medium_impact	0,33	0,69	0,9	4,68	7,56	P	0,57	P	0,64	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12901	12901	T	G	MI.20460	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	565	189	F	V	Ttt/Gtt	0,64	0,61	0	possibly_damaging	0,64	neutral	0,53	neutral	4,71	neutral	-0,7	deleterious	-6,53	neutral_impact	0,34	neutral	0,83	neutral	0,56	deleterious	2,45	19,13	0,36	0,5	neutral	0,45	disease	0,7	neutral	0,46	disease	0,53	1	neutral	0,61	neutral	0,45	neutral	-3	neutral	0,38	medium_impact	-0,98	medium_impact	0,26	medium_impact	-0,89	0,66	0,8	16,25	15,98	N	0,19	N	0,94	polymorphism	0,96	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12901	12901	T	C	MI.20461	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	565	189	F	L	Ttt/Ctt	0,64	0,61	0	benign	0,05	neutral	0,83	neutral	4,89	neutral	1,19	deleterious	-5,49	neutral_impact	-1,66	neutral	0,83	neutral	0,9	deleterious	0,44	6,97	0,44	0,55	disease	0,57	neutral	0,29	neutral	0,3	disease	0,58	2	neutral	0,09	deleterious	0,89	neutral	-6	neutral	0,13	medium_impact	0,47	medium_impact	0,61	low_impact	-2,72	0,64	0,8	16,25	15,98	N	0,24	N	0,64	polymorphism	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12902	12902	T	A	MI.20462	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	566	189	F	Y	tTt/tAt	-0,04	0,57	0	possibly_damaging	0,89	neutral	1	neutral	4,61	neutral	-1,35	deleterious	-2,85	low_impact	1,94	neutral	0,87	neutral	0,49	deleterious	4,01	23,6	0,36	0,5	disease	0,72	disease	0,67	neutral	0,48	disease	0,51	0	neutral	0,89	deleterious	0,56	neutral	-3	deleterious	0,63	low_impact	-1,61	high_impact	1,89	medium_impact	0,57	0,68	0,85	16,25	15,98	N	0,22	N	0,72	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12902	12902	T	C	MI.20463	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	566	189	F	S	tTt/tCt	-0,04	0,57	0	benign	0,22	neutral	0,51	neutral	4,61	neutral	-2,19	deleterious	-7,5	neutral_impact	0,3	neutral	0,82	neutral	0,63	deleterious	4,11	23,7	0,38	0,5	disease	0,66	disease	0,66	disease	0,55	disease	0,56	1	neutral	0,39	deleterious	0,65	neutral	-6	deleterious	0,66	medium_impact	-0,22	medium_impact	0,24	medium_impact	-0,93	0,61	0,8	16,25	15,98	N	0,24	N	0,97	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12902	12902	T	G	MI.20464	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	566	189	F	C	tTt/tGt	-0,04	0,57	0	probably_damaging	0,98	neutral	0,17	neutral	4,57	deleterious	-3,79	deleterious	-7,53	neutral_impact	0,38	neutral	0,78	neutral	0,48	deleterious	4,03	23,6	0,33	0,5	disease	0,79	disease	0,81	neutral	0,49	disease	0,73	5	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,75	low_impact	-2,35	medium_impact	-0,15	medium_impact	-0,86	0,38	0,8	16,25	15,98	N	0,26	N	0,98	polymorphism	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12903	12903	T	G	MI.20465	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	567	189	F	L	ttT/ttG	3,63	0,72	0	benign	0,05	neutral	0,83	neutral	4,89	neutral	1,19	deleterious	-5,49	neutral_impact	-1,66	neutral	0,83	neutral	0,9	deleterious	0,63	8,36	0,44	0,55	disease	0,57	neutral	0,29	neutral	0,3	disease	0,58	2	neutral	0,09	deleterious	0,89	neutral	-6	neutral	0,13	medium_impact	0,47	medium_impact	0,61	low_impact	-2,72	0,64	0,8	16,25	15,98	N	0,28	N	0,64	polymorphism	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12903	12903	T	A	MI.20466	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	567	189	F	L	ttT/ttA	3,63	0,72	0	benign	0,05	neutral	0,83	neutral	4,89	neutral	1,19	deleterious	-5,49	neutral_impact	-1,66	neutral	0,83	neutral	0,9	deleterious	0,74	9,09	0,44	0,55	disease	0,57	neutral	0,29	neutral	0,3	disease	0,58	2	neutral	0,09	deleterious	0,89	neutral	-6	neutral	0,13	medium_impact	0,47	medium_impact	0,61	low_impact	-2,72	0,64	0,8	16,25	15,98	N	0,27	N	0,64	polymorphism	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12904	12904	A	G	MI.20467	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	568	190	I	V	Atc/Gtc	-10,83	0	0	benign	0,12	neutral	0,55	neutral	4,64	neutral	-0,02	neutral	-0,62	neutral_impact	0,55	neutral	0,73	neutral	0,79	neutral	-1,01	0,02	0,76	0,8	neutral	0,48	neutral	0,17	neutral	0,25	neutral	0,3	4	neutral	0,36	deleterious	0,72	neutral	-6	neutral	0,12	medium_impact	0,08	medium_impact	0,28	medium_impact	-0,7	0,63	0,8	31,84	19,67	N	0,37	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12904	12904	A	T	MI.20468	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	568	190	I	F	Atc/Ttc	-10,83	0	0	benign	0,01	neutral	0,71	neutral	4,72	neutral	0,79	neutral	-1,45	neutral_impact	0,1	neutral	0,83	neutral	0,83	deleterious	0,22	4,88	0,57	0,65	neutral	0,35	disease	0,52	neutral	0,27	neutral	0,44	1	neutral	0,28	deleterious	0,85	neutral	-6	neutral	0,15	medium_impact	1,15	medium_impact	0,45	low_impact	-1,11	0,77	0,85	31,84	19,67	N	0,26	N	0,12	polymorphism	1	0,03	rs386829168	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12904	12904	A	C	MI.20469	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	568	190	I	L	Atc/Ctc	-10,83	0	0	benign	0,01	neutral	0,78	neutral	4,81	neutral	1,44	neutral	1,15	neutral_impact	-0,26	neutral	0,89	neutral	0,94	neutral	-0,9	0,03	0,4	0,5	neutral	0,35	neutral	0,18	neutral	0,21	neutral	0,31	4	neutral	0,2	deleterious	0,89	neutral	-6	neutral	0,11	medium_impact	1,15	medium_impact	0,54	low_impact	-1,44	0,77	0,85	31,84	19,67	N	0,42	N	0,03	polymorphism	1	0,01	rs386829168	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5983	5983	G	A	MI.2047	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	80	27	G	E	gGa/gAa	9,38	1	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-2,68	deleterious	-3,46	high_impact	4,75	damaging	0,56	damaging	0,03	deleterious	3,67	23,2	0,2	0,55	disease	0,58	disease	0,89	disease	0,71	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,57	0,9	4,68	7,56	P	0,69	P	0,93	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12905	12905	T	G	MI.20470	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	569	190	I	S	aTc/aGc	-3,26	0	0	possibly_damaging	0,49	neutral	0,51	neutral	4,6	neutral	-0,77	deleterious	-2,64	low_impact	1,04	neutral	0,83	neutral	0,95	neutral	1,01	10,74	0,5	0,6	neutral	0,42	neutral	0,48	neutral	0,28	neutral	0,46	1	neutral	0,49	deleterious	0,51	neutral	-3	neutral	0,2	medium_impact	-0,73	medium_impact	0,24	medium_impact	-0,25	0,56	0,8	31,84	19,67	N	0,29	N	0,11	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12905	12905	T	A	MI.20471	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	569	190	I	N	aTc/aAc	-3,26	0	0	possibly_damaging	0,8	neutral	0,35	neutral	4,56	neutral	-2,5	deleterious	-3,78	low_impact	1,7	neutral	0,73	neutral	0,55	neutral	1,41	12,84	0,4	0,5	disease	0,83	disease	0,72	neutral	0,46	disease	0,61	2	neutral	0,82	neutral	0,28	neutral	-3	deleterious	0,44	low_impact	-1,32	medium_impact	0,08	medium_impact	0,35	0,63	0,8	31,84	19,67	N	0,29	N	0,33	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12905	12905	T	C	MI.20472	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	569	190	I	T	aTc/aCc	-3,26	0	0	benign	0,41	neutral	0,54	neutral	4,59	neutral	-0,93	neutral	-1,8	low_impact	1,25	neutral	0,84	neutral	0,92	deleterious	-0,03	2,26	0,67	0,7	neutral	0,35	neutral	0,33	neutral	0,27	neutral	0,47	1	neutral	0,41	deleterious	0,57	neutral	-6	neutral	0,13	medium_impact	-0,6	medium_impact	0,27	medium_impact	-0,06	0,74	0,85	31,84	19,67	N	0,28	N	0,11	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12906	12906	C	G	MI.20473	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	570	190	I	M	atC/atG	0,18	0	0	benign	0,38	neutral	0,3	neutral	4,6	neutral	-0,72	neutral	0,19	low_impact	1,22	neutral	0,83	neutral	0,95	neutral	-0,08	1,88	0,66	0,7	disease	0,7	neutral	0,22	neutral	0,21	disease	0,51	0	neutral	0,65	neutral	0,46	neutral	-6	neutral	0,19	medium_impact	-0,54	medium_impact	0,03	medium_impact	-0,09	0,84	0,9	31,84	19,67	N	0,44	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12906	12906	C	A	MI.20474	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	570	190	I	M	atC/atA	0,18	0	0	benign	0,38	neutral	0,3	neutral	4,6	neutral	-0,72	neutral	0,19	low_impact	1,22	neutral	0,83	neutral	0,95	deleterious	0,39	6,54	0,66	0,7	disease	0,7	neutral	0,22	neutral	0,21	disease	0,51	0	neutral	0,65	neutral	0,46	neutral	-6	neutral	0,19	medium_impact	-0,54	medium_impact	0,03	medium_impact	-0,09	0,84	0,9	31,84	19,67	N	0,45	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12907	12907	C	A	MI.20475	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	571	191	L	M	Cta/Ata	-6,24	0	0	probably_damaging	0,98	neutral	0,62	neutral	4,56	neutral	-2,68	neutral	-0,36	neutral_impact	0,19	neutral	0,83	neutral	0,96	deleterious	0,88	9,94	0,35	0,5	disease	0,69	neutral	0,06	neutral	0,19	neutral	0,38	2	deleterious	0,98	neutral	0,32	neutral	-2	deleterious	0,64	low_impact	-2,35	medium_impact	0,35	low_impact	-1,03	0,68	0,85	20,07	15,51	N	0,4	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12907	12907	C	G	MI.20476	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	571	191	L	V	Cta/Gta	-6,24	0	0	possibly_damaging	0,86	neutral	0,6	neutral	4,64	neutral	-1,36	neutral	-0,78	neutral_impact	0,34	neutral	0,86	neutral	0,95	neutral	1,75	14,69	0,45	0,55	neutral	0,41	neutral	0,29	neutral	0,29	neutral	0,45	1	neutral	0,83	neutral	0,37	neutral	-3	deleterious	0,47	low_impact	-1,5	medium_impact	0,33	medium_impact	-0,89	0,42	0,8	20,07	15,51	N	0,27	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12908	12908	T	A	MI.20477	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	572	191	L	Q	cTa/cAa	-2,57	0	0	probably_damaging	0,99	neutral	0,36	neutral	4,54	deleterious	-3,43	deleterious	-3,18	low_impact	1,45	neutral	0,78	neutral	0,64	deleterious	3,94	23,5	0,3	0,45	disease	0,66	disease	0,57	disease	0,54	disease	0,63	3	deleterious	0,99	neutral	0,19	neutral	-2	deleterious	0,71	low_impact	-2,64	medium_impact	0,1	medium_impact	0,12	0,5	0,8	20,07	15,51	N	0,26	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12908	12908	T	C	MI.20478	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	572	191	L	P	cTa/cCa	-2,57	0	0	probably_damaging	0,99	neutral	0,27	neutral	4,52	deleterious	-4,76	deleterious	-3,91	low_impact	1,8	damaging	0,58	neutral	0,46	deleterious	3,79	23,4	0,25	0,45	disease	0,81	disease	0,84	disease	0,69	disease	0,8	6	deleterious	0,99	neutral	0,14	neutral	-2	deleterious	0,82	low_impact	-2,64	medium_impact	-0,01	medium_impact	0,44	0,5	0,8	20,07	15,51	N	0,25	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12908	12908	T	G	MI.20479	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	572	191	L	R	cTa/cGa	-2,57	0	0	probably_damaging	0,98	neutral	0,38	neutral	4,56	deleterious	-3,91	deleterious	-3,37	low_impact	1,67	neutral	0,74	neutral	0,52	deleterious	4,05	23,7	0,3	0,45	disease	0,74	disease	0,8	disease	0,59	disease	0,76	5	deleterious	0,98	neutral	0,2	neutral	-2	deleterious	0,79	low_impact	-2,35	medium_impact	0,12	medium_impact	0,32	0,5	0,8	20,07	15,51	N	0,25	N	0,93	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5985	5985	G	T	MI.2048	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	82	28	V	F	Gtc/Ttc	-8,66	0	0	benign	0,14	neutral	0,18	neutral	2,68	neutral	-1,41	neutral	-0,54	neutral_impact	-0,07	damaging	0,59	neutral	0,6	deleterious	1,86	15,32	0,3	0,55	neutral	0,32	disease	0,83	neutral	0,22	disease	0,51	0	neutral	0,79	deleterious	0,52	neutral	-6	neutral	0,27	medium_impact	-0,01	medium_impact	-0,17	low_impact	-1,16	0,73	0,9	14,81	54,58	N	0,42	N	0,48	polymorphism	1	0,01	rs386828982	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12910	12910	C	A	MI.20480	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	574	192	H	N	Cac/Aac	-12,66	0	0	benign	0,08	neutral	0,43	neutral	4,69	neutral	1,32	neutral	-0,72	neutral_impact	-1,29	neutral	0,77	neutral	0,97	neutral	1,15	11,48	0,7	0,75	neutral	0,38	neutral	0,19	neutral	0,34	neutral	0,34	3	neutral	0,51	deleterious	0,68	neutral	-6	deleterious	0,68	medium_impact	0,26	medium_impact	0,17	low_impact	-2,38	0,69	0,85	21,72	16,21	N	0,38	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12910	12910	C	G	MI.20481	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	574	192	H	D	Cac/Gac	-12,66	0	0	possibly_damaging	0,77	neutral	0,2	neutral	4,63	neutral	-0,74	deleterious	-3,68	neutral_impact	0,58	neutral	0,75	neutral	0,61	deleterious	3,84	23,4	0,41	0,5	disease	0,64	disease	0,74	disease	0,75	disease	0,79	6	neutral	0,87	neutral	0,22	neutral	-3	deleterious	0,81	low_impact	-1,24	medium_impact	-0,1	medium_impact	-0,67	0,62	0,8	21,72	16,21	N	0,34	N	0,71	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12910	12910	C	T	MI.20482	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	574	192	H	Y	Cac/Tac	-12,66	0	0	benign	0,05	neutral	1	neutral	4,69	neutral	1,26	neutral	-2,47	neutral_impact	-0,26	neutral	0,88	neutral	0,87	deleterious	2,51	19,51	0,73	0,75	disease	0,58	disease	0,63	neutral	0,44	neutral	0,5	0	neutral	0,05	deleterious	0,98	neutral	-6	deleterious	0,78	medium_impact	0,47	high_impact	1,89	low_impact	-1,44	0,33	0,8	21,72	16,21	N	0,24	N	0,33	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12911	12911	A	G	MI.20483	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	575	192	H	R	cAc/cGc	-0,27	0	0	possibly_damaging	0,82	neutral	0,34	neutral	4,64	neutral	-0,08	deleterious	-3,65	low_impact	1,22	neutral	0,8	neutral	0,65	deleterious	2,79	21,3	0,68	0,7	disease	0,59	disease	0,75	disease	0,7	disease	0,76	5	neutral	0,84	neutral	0,26	neutral	-3	deleterious	0,81	low_impact	-1,37	medium_impact	0,07	medium_impact	-0,09	0,36	0,8	21,72	16,21	N	0,25	N	0,67	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12911	12911	A	T	MI.20484	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	575	192	H	L	cAc/cTc	-0,27	0	0	possibly_damaging	0,66	neutral	0,9	neutral	4,85	neutral	2,97	deleterious	-5,89	neutral_impact	-0,06	neutral	0,81	neutral	0,64	deleterious	3,65	23,2	0,48	0,55	neutral	0,4	disease	0,74	disease	0,65	disease	0,7	4	neutral	0,61	deleterious	0,62	neutral	-3	deleterious	0,74	low_impact	-1,02	medium_impact	0,76	low_impact	-1,26	0,29	0,8	21,72	16,21	N	0,24	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12911	12911	A	C	MI.20485	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	575	192	H	P	cAc/cCc	-0,27	0	0	probably_damaging	0,97	neutral	0,26	neutral	4,63	neutral	-0,94	deleterious	-5,42	low_impact	1,34	neutral	0,7	neutral	0,48	deleterious	3,12	22,6	0,4	0,5	disease	0,83	disease	0,9	disease	0,78	disease	0,85	7	neutral	0,97	neutral	0,15	neutral	-2	deleterious	0,89	low_impact	-2,18	medium_impact	-0,02	medium_impact	0,02	0,36	0,8	21,72	16,21	N	0,3	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12912	12912	C	G	MI.20486	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	576	192	H	Q	caC/caG	3,63	0,07	0	probably_damaging	0,91	neutral	0,32	neutral	4,66	neutral	0,66	deleterious	-3,44	neutral_impact	0,06	neutral	0,83	neutral	0,81	deleterious	3,54	23,1	0,74	0,75	disease	0,59	disease	0,52	disease	0,59	disease	0,65	3	neutral	0,92	neutral	0,21	neutral	-2	deleterious	0,75	low_impact	-1,7	medium_impact	0,05	low_impact	-1,15	0,62	0,8	21,72	16,21	N	0,33	N	0,64	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12912	12912	C	A	MI.20487	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	576	192	H	Q	caC/caA	3,63	0,07	0	probably_damaging	0,91	neutral	0,32	neutral	4,66	neutral	0,66	deleterious	-3,44	neutral_impact	0,06	neutral	0,83	neutral	0,81	deleterious	3,76	23,3	0,74	0,75	disease	0,59	disease	0,52	disease	0,59	disease	0,65	3	neutral	0,92	neutral	0,21	neutral	-2	deleterious	0,75	low_impact	-1,7	medium_impact	0,05	low_impact	-1,15	0,62	0,8	21,72	16,21	N	0,33	N	0,64	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12913	12913	T	G	MI.20488	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	577	193	S	A	Tcc/Gcc	-0,73	0	0	benign	0,02	neutral	0,96	neutral	4,6	neutral	0,11	neutral	-1,16	neutral_impact	0,54	neutral	0,84	neutral	0,87	deleterious	0,5	7,46	0,52	0,6	neutral	0,37	neutral	0,32	neutral	0,41	neutral	0,46	1	neutral	0,01	deleterious	0,97	neutral	-6	neutral	0,13	medium_impact	0,86	medium_impact	1	medium_impact	-0,71	0,73	0,85	32,34	19,26	N	0,25	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12913	12913	T	A	MI.20489	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	577	193	S	T	Tcc/Acc	-0,73	0	0	benign	0,02	neutral	0,66	neutral	4,76	neutral	0,85	neutral	-0,72	neutral_impact	-0,37	neutral	0,9	neutral	0,99	deleterious	0,57	7,91	0,48	0,55	neutral	0,37	neutral	0,22	neutral	0,23	neutral	0,35	3	neutral	0,31	deleterious	0,82	neutral	-6	neutral	0,11	medium_impact	0,86	medium_impact	0,39	low_impact	-1,54	0,86	0,9	32,34	19,26	N	0,39	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5985	5985	G	C	MI.2049	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	82	28	V	L	Gtc/Ctc	-8,66	0	0	benign	0,01	neutral	0,32	neutral	2,86	neutral	-0,03	neutral	0,68	neutral_impact	-1,01	neutral	0,66	neutral	0,77	deleterious	-0,06	2,08	0,4	0,55	neutral	0,16	neutral	0,39	neutral	0,16	neutral	0,44	1	neutral	0,67	deleterious	0,66	neutral	-6	neutral	0,14	medium_impact	1,12	medium_impact	0,01	low_impact	-2,03	0,61	0,9	14,81	54,58	N	0,53	P	0,27	polymorphism	1	0,01	rs386828982	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12913	12913	T	C	MI.20490	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	577	193	S	P	Tcc/Ccc	-0,73	0	0	possibly_damaging	0,66	neutral	0,33	neutral	4,51	deleterious	-3,71	deleterious	-2,95	medium_impact	2,31	damaging	0,59	neutral	0,41	deleterious	2,64	20,5	0,25	0,45	disease	0,9	disease	0,85	disease	0,54	disease	0,78	6	neutral	0,73	neutral	0,34	NA	0	deleterious	0,72	low_impact	-1,02	medium_impact	0,06	medium_impact	0,91	0,68	0,85	32,34	19,26	N	0,29	N	0,65	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12914	12914	C	T	MI.20491	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	578	193	S	F	tCc/tTc	-5,78	0	0	benign	0,38	neutral	0,74	neutral	4,53	neutral	-1,7	neutral	-1,92	neutral_impact	-0,98	neutral	0,81	neutral	0,84	deleterious	2,67	20,6	0,45	0,55	disease	0,59	disease	0,6	neutral	0,35	neutral	0,48	0	neutral	0,27	deleterious	0,68	neutral	-6	deleterious	0,69	medium_impact	-0,54	medium_impact	0,48	low_impact	-2,1	0,35	0,8	32,34	19,26	N	0,21	N	0,2	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12914	12914	C	G	MI.20492	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	578	193	S	C	tCc/tGc	-5,78	0	0	possibly_damaging	0,9	neutral	0,2	neutral	4,51	deleterious	-4,82	neutral	-2,05	low_impact	1,06	neutral	0,86	neutral	0,67	deleterious	2,38	18,66	0,34	0,5	disease	0,85	disease	0,66	neutral	0,43	disease	0,6	2	neutral	0,94	neutral	0,15	neutral	-3	deleterious	0,71	low_impact	-1,65	medium_impact	-0,1	medium_impact	-0,23	0,66	0,8	32,34	19,26	N	0,32	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12914	12914	C	A	MI.20493	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	578	193	S	Y	tCc/tAc	-5,78	0	0	benign	0,01	neutral	1	neutral	4,53	neutral	-2,2	neutral	-2,1	neutral_impact	0,18	neutral	0,9	neutral	0,82	deleterious	2,41	18,86	0,34	0,5	disease	0,54	disease	0,65	neutral	0,37	neutral	0,47	1	neutral	0,01	deleterious	1	neutral	-6	deleterious	0,69	medium_impact	1,15	high_impact	1,89	low_impact	-1,04	0,68	0,85	32,34	19,26	N	0,19	N	0,05	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12916	12916	A	G	MI.20494	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	580	194	N	D	Aac/Gac	-6,7	0	0	probably_damaging	1	neutral	0,35	neutral	4,56	neutral	-1,28	deleterious	-4,65	low_impact	1,08	neutral	0,72	damaging	0,14	deleterious	3,84	23,4	0,62	0,65	disease	0,64	disease	0,67	disease	0,6	disease	0,6	2	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,77	low_impact	-3,6	medium_impact	0,08	medium_impact	-0,22	0,65	0,8	5,14	7,18	N	0,23	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12916	12916	A	C	MI.20495	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	580	194	N	H	Aac/Cac	-6,7	0	0	probably_damaging	1	neutral	0,56	neutral	4,55	neutral	-2,12	deleterious	-4,72	low_impact	1,62	neutral	0,7	damaging	0,12	deleterious	3,08	22,5	0,44	0,55	disease	0,85	disease	0,71	disease	0,63	disease	0,72	4	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	0,29	medium_impact	0,28	0,51	0,8	5,14	7,18	N	0,17	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12916	12916	A	T	MI.20496	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	580	194	N	Y	Aac/Tac	-6,7	0	0	probably_damaging	1	neutral	1	neutral	4,54	deleterious	-3,04	deleterious	-7,53	medium_impact	2,48	neutral	0,74	damaging	0,1	deleterious	3,74	23,3	0,29	0,45	disease	0,82	disease	0,82	disease	0,62	disease	0,71	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,83	low_impact	-3,6	high_impact	1,89	medium_impact	1,06	0,46	0,8	5,14	7,18	N	0,17	N	0,99	polymorphism	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12917	12917	A	G	MI.20497	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	581	194	N	S	aAc/aGc	6,61	1	0	probably_damaging	1	neutral	0,59	neutral	4,74	neutral	-0,66	deleterious	-4,38	neutral_impact	0,21	neutral	0,73	damaging	0,22	deleterious	3,11	22,5	0,61	0,65	disease	0,71	disease	0,52	neutral	0,46	neutral	0,48	0	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,77	low_impact	-3,6	medium_impact	0,32	low_impact	-1,01	0,32	0,8	5,14	7,18	N	0,42	N	0,82	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12917	12917	A	C	MI.20498	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	581	194	N	T	aAc/aCc	6,61	1	0	probably_damaging	1	neutral	0,55	neutral	4,57	neutral	-0,3	deleterious	-5,49	medium_impact	2,02	neutral	0,7	damaging	0,15	deleterious	3,42	23	0,44	0,55	disease	0,75	disease	0,66	disease	0,65	disease	0,55	1	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,28	medium_impact	0,64	0,44	0,8	5,14	7,18	N	0,42	N	0,94	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12917	12917	A	T	MI.20499	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	581	194	N	I	aAc/aTc	6,61	1	0	probably_damaging	1	neutral	0,45	neutral	4,53	neutral	-2,53	deleterious	-8,43	medium_impact	3,04	neutral	0,71	damaging	0,1	deleterious	3,98	23,6	0,29	0,45	disease	0,86	disease	0,88	disease	0,63	disease	0,76	5	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,18	medium_impact	1,57	0,39	0,8	5,14	7,18	N	0,51	P	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8621	8621	C	G	MI.205	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	95	32	P	R	cCc/cGc	0,13	0	0	probably_damaging	1	neutral	0,05	neutral	4,45	neutral	1,6	deleterious	-7,15	medium_impact	3,12	neutral	0,86	damaging	0,14	deleterious	3,39	23	0,4	0,65	neutral	0,41	disease	0,86	disease	0,55	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	-0,43	medium_impact	1,58	0,59	0,9	29,2	19,38	N	0,32	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5985	5985	G	A	MI.2050	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	82	28	V	I	Gtc/Atc	-8,66	0	0	benign	0	deleterious	0,01	neutral	2,72	neutral	-0,45	neutral	0,1	neutral_impact	0,06	neutral	0,66	neutral	0,73	neutral	1,44	12,98	0,58	0,65	neutral	0,27	neutral	0,32	neutral	0,21	neutral	0,45	1	deleterious	0,99	deleterious	0,51	neutral	-2	neutral	0,15	high_impact	2,07	medium_impact	-0,92	low_impact	-1,04	0,81	0,9	14,81	54,58	N	0,54	P	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12918	12918	C	G	MI.20500	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	582	194	N	K	aaC/aaG	4,54	1	0	probably_damaging	1	neutral	0,51	neutral	4,6	neutral	-0,96	deleterious	-5,57	low_impact	1,91	neutral	0,7	damaging	0,11	deleterious	3,97	23,6	0,59	0,65	disease	0,63	disease	0,75	disease	0,69	disease	0,63	3	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	0,24	medium_impact	0,54	0,72	0,85	5,14	7,18	N	0,34	N	1	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12918	12918	C	A	MI.20501	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	582	194	N	K	aaC/aaA	4,54	1	0	probably_damaging	1	neutral	0,51	neutral	4,6	neutral	-0,96	deleterious	-5,57	low_impact	1,91	neutral	0,7	damaging	0,11	deleterious	4,39	24,1	0,59	0,65	disease	0,63	disease	0,75	disease	0,69	disease	0,63	3	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	0,24	medium_impact	0,54	0,72	0,85	5,14	7,18	N	0,35	N	1	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12919	12919	T	C	MI.20502	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	583	195	S	P	Tca/Cca	-0,04	0	0	probably_damaging	1	neutral	0,28	neutral	4,34	deleterious	-4,66	deleterious	-4,08	high_impact	4	damaging	0,59	damaging	0,17	deleterious	4,04	23,7	0,28	0,45	disease	0,92	disease	0,9	disease	0,72	disease	0,83	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,01	high_impact	2,45	0,46	0,8	13,6	17,03	N	0,36	N	0,95	disease_causing	0,91	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12919	12919	T	G	MI.20503	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	583	195	S	A	Tca/Gca	-0,04	0	0	probably_damaging	1	neutral	0,82	neutral	4,41	neutral	-1,84	neutral	-2,1	medium_impact	2,61	neutral	0,81	neutral	0,94	deleterious	3,65	23,2	0,42	0,55	disease	0,61	disease	0,57	disease	0,63	disease	0,51	0	deleterious	1	neutral	0,41	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,6	medium_impact	1,18	0,72	0,85	13,6	17,03	N	0,23	N	0,43	polymorphism	0,68	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12919	12919	T	A	MI.20504	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	583	195	S	T	Tca/Aca	-0,04	0	0	probably_damaging	1	neutral	0,58	neutral	4,49	neutral	-0,24	neutral	-1,33	neutral_impact	0,5	neutral	0,78	neutral	0,95	deleterious	2,57	19,9	0,39	0,5	neutral	0,43	neutral	0,32	neutral	0,38	neutral	0,43	1	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	0,31	medium_impact	-0,75	0,71	0,85	13,6	17,03	N	0,27	N	0,06	disease_causing	0,61	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12920	12920	C	T	MI.20505	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	584	195	S	L	tCa/tTa	-1,65	0	0	probably_damaging	1	neutral	0,78	neutral	4,39	neutral	-2,75	deleterious	-4,78	medium_impact	2,92	neutral	0,7	damaging	0,19	deleterious	4,66	24,5	0,25	0,45	disease	0,86	disease	0,87	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,54	medium_impact	1,46	0,8	0,85	13,6	17,03	N	0,21	N	0,86	disease_causing	0,94	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12920	12920	C	G	MI.20506	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	584	195	S	W	tCa/tGa	-1,65	0	0	probably_damaging	1	neutral	0,22	neutral	4,32	deleterious	-7,54	deleterious	-5,84	high_impact	4,2	neutral	0,71	damaging	0,18	deleterious	4,35	24,1	0,25	0,45	disease	0,98	disease	0,91	disease	0,76	disease	0,86	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,07	high_impact	2,63	0,44	0,8	13,6	17,03	N	0,35	N	0,98	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12922	12922	T	G	MI.20507	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	586	196	W	G	Tga/Gga	-2,11	0	0	probably_damaging	1	neutral	0,38	neutral	4,54	neutral	-0,23	deleterious	-12,82	high_impact	3,67	neutral	0,63	neutral	0,44	deleterious	3,91	23,5	0,4	0,5	disease	0,84	disease	0,83	disease	0,84	disease	0,77	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,12	high_impact	2,15	0,21	0,8	15,26	7,04	N	0,46	N	0,97	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12922	12922	T	C	MI.20508	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	586	196	W	R	Tga/Cga	-2,11	0	0	probably_damaging	1	neutral	0,39	neutral	4,54	neutral	-2,41	deleterious	-13,81	high_impact	4,01	neutral	0,63	neutral	0,31	deleterious	3,54	23,1	0,43	0,55	disease	0,82	disease	0,92	disease	0,87	disease	0,82	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,13	high_impact	2,46	0,24	0,8	15,26	7,04	N	0,47	N	0,97	disease_causing	0,99	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12923	12923	G	T	MI.20509	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	587	196	W	L	tGa/tTa	4,54	1	0	probably_damaging	1	neutral	0,75	neutral	4,86	neutral	1,83	deleterious	-12,82	low_impact	0,92	neutral	0,64	neutral	0,57	deleterious	4,19	23,8	0,4	0,5	disease	0,57	disease	0,78	disease	0,79	disease	0,62	2	deleterious	1	neutral	0,38	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	0,5	medium_impact	-0,36	0,21	0,8	15,26	7,04	N	0,42	N	0,97	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5986	5986	T	C	MI.2051	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	83	28	V	A	gTc/gCc	4,06	0,99	0	benign	0	deleterious	0,02	neutral	2,77	neutral	0,54	neutral	-1,02	low_impact	1,3	neutral	0,61	neutral	0,81	neutral	1,51	13,35	0,39	0,55	neutral	0,31	neutral	0,5	neutral	0,45	neutral	0,5	0	neutral	0,98	deleterious	0,51	neutral	-2	neutral	0,19	high_impact	2,07	medium_impact	-0,75	medium_impact	0,1	0,44	0,9	14,81	54,58	P	0,58	P	0,28	polymorphism	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12923	12923	G	C	MI.20510	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	587	196	W	S	tGa/tCa	4,54	1	0	probably_damaging	1	neutral	0,64	neutral	4,56	neutral	-1,01	deleterious	-13,81	medium_impact	2,77	neutral	0,65	neutral	0,42	deleterious	4,01	23,6	0,37	0,5	disease	0,74	disease	0,9	disease	0,82	disease	0,81	6	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,37	medium_impact	1,33	0,23	0,8	15,26	7,04	N	0,43	N	0,95	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12924	12924	A	C	MI.20511	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	588	196	W	C	tgA/tgC	4,08	1	0	probably_damaging	1	neutral	0,18	neutral	4,56	deleterious	-3,21	deleterious	-12,82	high_impact	4,36	neutral	0,65	damaging	0,28	deleterious	4,05	23,7	0,33	0,5	neutral	0,46	disease	0,91	disease	0,83	disease	0,8	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	-0,13	high_impact	2,78	0,18	0,8	15,26	7,04	P	0,56	P	0,98	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12924	12924	A	T	MI.20512	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	588	196	W	C	tgA/tgT	4,08	1	0	probably_damaging	1	neutral	0,18	neutral	4,56	deleterious	-3,21	deleterious	-12,82	high_impact	4,36	neutral	0,65	damaging	0,28	deleterious	4,12	23,8	0,33	0,5	neutral	0,46	disease	0,91	disease	0,83	disease	0,8	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	-0,13	high_impact	2,78	0,18	0,8	15,26	7,04	P	0,57	P	0,98	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12925	12925	G	C	MI.20513	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	589	197	D	H	Gac/Cac	0,18	0,98	0	probably_damaging	0,98	neutral	0,57	neutral	4,56	deleterious	-3,8	deleterious	-4,1	low_impact	1,82	neutral	0,76	neutral	0,46	deleterious	3,59	23,2	0,47	0,55	disease	0,68	disease	0,77	disease	0,67	disease	0,73	5	neutral	0,97	neutral	0,3	neutral	-2	deleterious	0,75	low_impact	-2,35	medium_impact	0,3	medium_impact	0,46	0,55	0,8	4,48	9,19	N	0,33	N	0,71	polymorphism	0,68	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12925	12925	G	A	MI.20514	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	589	197	D	N	Gac/Aac	0,18	0,98	0	benign	0,17	neutral	0,46	neutral	4,68	neutral	-1,12	deleterious	-3,03	neutral_impact	-0,42	neutral	0,8	neutral	0,85	deleterious	2,58	19,98	0,82	0,85	disease	0,53	disease	0,66	neutral	0,43	neutral	0,48	0	neutral	0,45	deleterious	0,65	neutral	-6	deleterious	0,56	medium_impact	-0,09	medium_impact	0,19	low_impact	-1,59	0,78	0,85	4,48	9,19	N	0,32	N	0,47	polymorphism	0,92	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12925	12925	G	T	MI.20515	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	589	197	D	Y	Gac/Tac	0,18	0,98	0	probably_damaging	0,98	neutral	1	neutral	4,55	deleterious	-4,72	deleterious	-6,11	medium_impact	3,21	neutral	0,74	neutral	0,48	deleterious	3,88	23,5	0,43	0,55	disease	0,76	disease	0,89	disease	0,67	disease	0,78	6	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,82	low_impact	-2,35	high_impact	1,89	medium_impact	1,73	0,3	0,8	4,48	9,19	N	0,33	N	0,97	polymorphism	0,5	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12926	12926	A	G	MI.20516	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	590	197	D	G	gAc/gGc	5	1	0	possibly_damaging	0,74	neutral	0,43	neutral	4,55	neutral	-2,33	deleterious	-5,15	medium_impact	2,01	neutral	0,75	neutral	0,59	deleterious	3,55	23,1	0,4	0,5	neutral	0,24	disease	0,75	disease	0,64	disease	0,66	3	neutral	0,74	neutral	0,35	NA	0	deleterious	0,49	low_impact	-1,18	medium_impact	0,17	medium_impact	0,63	0,38	0,8	4,48	9,19	N	0,5	N	0,85	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12926	12926	A	T	MI.20517	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	590	197	D	V	gAc/gTc	5	1	0	probably_damaging	0,96	neutral	0,58	neutral	4,54	deleterious	-3,84	deleterious	-6,14	medium_impact	2,52	neutral	0,78	neutral	0,57	deleterious	3,47	23	0,45	0,55	disease	0,62	disease	0,83	disease	0,64	disease	0,75	5	neutral	0,95	neutral	0,31	deleterious	1	deleterious	0,68	low_impact	-2,06	medium_impact	0,31	medium_impact	1,1	0,33	0,8	4,48	9,19	N	0,39	N	0,95	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12926	12926	A	C	MI.20518	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	590	197	D	A	gAc/gCc	5	1	0	possibly_damaging	0,83	neutral	0,71	neutral	4,58	neutral	-2,11	deleterious	-5,15	medium_impact	2,4	neutral	0,76	neutral	0,65	deleterious	1,94	15,8	0,5	0,6	neutral	0,47	disease	0,74	disease	0,65	disease	0,66	3	neutral	0,8	neutral	0,44	NA	0	deleterious	0,5	low_impact	-1,4	medium_impact	0,45	medium_impact	0,99	0,55	0,8	4,48	9,19	N	0,45	N	0,83	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12927	12927	C	G	MI.20519	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	591	197	D	E	gaC/gaG	5,46	1	0	benign	0,08	neutral	0,55	neutral	4,66	neutral	-1,28	neutral	-0,28	neutral_impact	0,17	neutral	0,85	neutral	0,97	neutral	-0,79	0,04	0,72	0,75	neutral	0,27	neutral	0,2	neutral	0,16	neutral	0,38	2	neutral	0,37	deleterious	0,74	neutral	-6	neutral	0,13	medium_impact	0,26	medium_impact	0,28	low_impact	-1,05	0,59	0,8	4,48	9,19	P	0,53	P	0,14	disease_causing	0,97	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5986	5986	T	A	MI.2052	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	83	28	V	D	gTc/gAc	4,06	0,99	0	benign	0,12	deleterious	0	neutral	2,55	neutral	-1,16	neutral	-2,17	medium_impact	2,66	damaging	0,49	neutral	0,47	deleterious	2,78	21,3	0,09	0,55	disease	0,77	disease	0,87	disease	0,61	disease	0,8	6	deleterious	1	neutral	0,44	deleterious	1	neutral	0,38	medium_impact	0,06	low_impact	-1,48	medium_impact	1,36	0,68	0,9	14,81	54,58	P	0,51	P	0,68	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12927	12927	C	A	MI.20520	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	591	197	D	E	gaC/gaA	5,46	1	0	benign	0,08	neutral	0,55	neutral	4,66	neutral	-1,28	neutral	-0,28	neutral_impact	0,17	neutral	0,85	neutral	0,97	neutral	-0,48	0,25	0,72	0,75	neutral	0,27	neutral	0,2	neutral	0,16	neutral	0,38	2	neutral	0,37	deleterious	0,74	neutral	-6	neutral	0,13	medium_impact	0,26	medium_impact	0,28	low_impact	-1,05	0,59	0,8	4,48	9,19	P	0,53	P	0,14	disease_causing	0,97	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12928	12928	C	T	MI.20521	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	592	198	P	S	Cca/Tca	-5,78	0	0	benign	0,41	neutral	0,88	neutral	4,67	neutral	1,53	neutral	1,02	neutral_impact	-0,46	neutral	0,79	neutral	0,72	deleterious	3,69	23,3	0,54	0,6	neutral	0,42	neutral	0,18	neutral	0,41	neutral	0,31	4	neutral	0,31	deleterious	0,74	neutral	-6	deleterious	0,6	medium_impact	-0,6	medium_impact	0,71	low_impact	-1,62	0,42	0,8	9,45	11,24	N	0,23	N	0,37	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12928	12928	C	A	MI.20522	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	592	198	P	T	Cca/Aca	-5,78	0	0	benign	0,41	neutral	0,73	neutral	4,71	neutral	2,47	neutral	1,59	neutral_impact	-0,34	neutral	0,82	neutral	0,82	deleterious	3,56	23,1	0,55	0,6	neutral	0,41	neutral	0,17	neutral	0,4	neutral	0,3	4	neutral	0,31	deleterious	0,66	neutral	-6	deleterious	0,55	medium_impact	-0,6	medium_impact	0,47	low_impact	-1,51	0,81	0,85	9,45	11,24	N	0,26	N	0,36	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12928	12928	C	G	MI.20523	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	592	198	P	A	Cca/Gca	-5,78	0	0	benign	0,27	neutral	0,96	neutral	4,72	neutral	2,64	neutral	1,59	neutral_impact	-0,2	neutral	0,83	neutral	0,77	deleterious	2,68	20,7	0,41	0,5	neutral	0,23	neutral	0,12	neutral	0,42	neutral	0,33	3	neutral	0,2	deleterious	0,85	neutral	-6	deleterious	0,46	medium_impact	-0,34	medium_impact	1	low_impact	-1,39	0,85	0,9	9,45	11,24	N	0,28	N	0,38	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12929	12929	C	T	MI.20524	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	593	198	P	L	cCa/cTa	-3,03	0	0	benign	0,01	neutral	0,71	neutral	4,89	neutral	4,29	neutral	5,12	neutral_impact	-3,6	neutral	0,87	neutral	0,97	neutral	-0,27	0,76	0,58	0,65	neutral	0,2	neutral	0,16	neutral	0,12	neutral	0,24	5	neutral	0,27	deleterious	0,85	neutral	-6	neutral	0,11	medium_impact	1,15	medium_impact	0,45	low_impact	-4,49	0,91	0,95	9,45	11,24	N	0,33	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12929	12929	C	G	MI.20525	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	593	198	P	R	cCa/cGa	-3,03	0	0	possibly_damaging	0,66	neutral	0,66	neutral	4,65	neutral	0,58	neutral	0,61	neutral_impact	0,34	neutral	0,75	neutral	0,47	deleterious	3,49	23,1	0,35	0,5	disease	0,52	neutral	0,43	disease	0,6	disease	0,52	0	neutral	0,6	deleterious	0,5	neutral	-3	deleterious	0,7	low_impact	-1,02	medium_impact	0,39	medium_impact	-0,89	0,75	0,85	9,45	11,24	N	0,27	N	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12929	12929	C	A	MI.20526	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	593	198	P	Q	cCa/cAa	-3,03	0	0	possibly_damaging	0,73	neutral	0,68	neutral	4,65	neutral	0,41	neutral	0,73	neutral_impact	0,34	neutral	0,79	neutral	0,59	deleterious	4	23,6	0,29	0,45	disease	0,51	neutral	0,25	neutral	0,46	neutral	0,32	4	neutral	0,68	deleterious	0,48	neutral	-3	deleterious	0,66	low_impact	-1,16	medium_impact	0,41	medium_impact	-0,89	0,74	0,85	9,45	11,24	N	0,26	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12931	12931	C	G	MI.20527	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	595	199	Q	E	Caa/Gaa	-13,12	0	0	probably_damaging	1	neutral	0,4	neutral	4,7	neutral	0,7	deleterious	-2,88	low_impact	1,07	neutral	0,77	damaging	0,18	deleterious	3,09	22,5	0,52	0,6	disease	0,53	disease	0,63	disease	0,68	neutral	0,5	0	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,77	low_impact	-3,6	medium_impact	0,14	medium_impact	-0,23	0,66	0,8	2,99	7,87	N	0,24	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12931	12931	C	A	MI.20528	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	595	199	Q	K	Caa/Aaa	-13,12	0	0	probably_damaging	1	neutral	0,39	neutral	4,65	neutral	0,06	deleterious	-3,84	low_impact	1,53	neutral	0,73	damaging	0,11	deleterious	3,97	23,6	0,49	0,55	disease	0,51	disease	0,78	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,13	medium_impact	0,2	0,5	0,8	2,99	7,87	N	0,27	N	0,96	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12932	12932	A	C	MI.20529	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	596	199	Q	P	cAa/cCa	2,02	0,95	0	probably_damaging	1	neutral	0,27	neutral	4,63	neutral	-0,27	deleterious	-5,78	medium_impact	2	neutral	0,65	damaging	0,27	deleterious	3,27	22,8	0,32	0,5	disease	0,81	disease	0,84	disease	0,77	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	-0,01	medium_impact	0,62	0,55	0,8	2,99	7,87	N	0,36	N	0,95	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5986	5986	T	G	MI.2053	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	83	28	V	G	gTc/gGc	4,06	0,99	0	benign	0,06	deleterious	0	neutral	2,58	neutral	0,7	neutral	-2,18	low_impact	1,5	damaging	0,57	neutral	0,5	deleterious	1,87	15,43	0,19	0,55	disease	0,62	disease	0,71	neutral	0,5	disease	0,54	1	deleterious	1	deleterious	0,47	neutral	-2	neutral	0,27	medium_impact	0,37	low_impact	-1,48	medium_impact	0,29	0,57	0,9	14,81	54,58	N	0,45	N	0,54	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12932	12932	A	G	MI.20530	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	596	199	Q	R	cAa/cGa	2,02	0,95	0	probably_damaging	1	neutral	0,39	neutral	4,64	neutral	-0,05	deleterious	-3,84	low_impact	1,88	neutral	0,65	damaging	0,11	deleterious	3,37	22,9	0,62	0,65	disease	0,52	disease	0,79	disease	0,79	disease	0,75	5	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,81	low_impact	-3,6	medium_impact	0,13	medium_impact	0,51	0,42	0,8	2,99	7,87	N	0,35	N	0,85	disease_causing	0,96	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12932	12932	A	T	MI.20531	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	596	199	Q	L	cAa/cTa	2,02	0,95	0	probably_damaging	1	neutral	0,7	neutral	4,66	neutral	0,19	deleterious	-6,28	neutral_impact	0,8	neutral	0,68	damaging	0,11	deleterious	3,65	23,2	0,41	0,5	disease	0,75	disease	0,79	disease	0,69	disease	0,65	3	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,82	low_impact	-3,6	medium_impact	0,44	medium_impact	-0,47	0,39	0,8	2,99	7,87	N	0,28	N	0,96	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12933	12933	A	C	MI.20532	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	597	199	Q	H	caA/caC	6,84	1	0	probably_damaging	1	neutral	0,55	neutral	4,57	neutral	-1,81	deleterious	-4,8	low_impact	1,72	neutral	0,72	neutral	0,3	deleterious	3,34	22,9	0,51	0,6	disease	0,77	disease	0,68	disease	0,56	disease	0,55	1	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,81	low_impact	-3,6	medium_impact	0,28	medium_impact	0,37	0,67	0,85	2,99	7,87	N	0,45	N	0,94	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12933	12933	A	T	MI.20533	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	597	199	Q	H	caA/caT	6,84	1	0	probably_damaging	1	neutral	0,55	neutral	4,57	neutral	-1,81	deleterious	-4,8	low_impact	1,72	neutral	0,72	neutral	0,3	deleterious	3,54	23,1	0,51	0,6	disease	0,77	disease	0,68	disease	0,56	disease	0,55	1	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,81	low_impact	-3,6	medium_impact	0,28	medium_impact	0,37	0,67	0,85	2,99	7,87	N	0,46	N	0,94	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12934	12934	C	G	MI.20534	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	598	200	Q	E	Caa/Gaa	3,17	1	0	probably_damaging	1	neutral	0,29	neutral	4,74	neutral	0,43	deleterious	-2,93	neutral_impact	-0,8	neutral	0,69	neutral	0,31	deleterious	3,03	22,3	0,58	0,65	neutral	0,47	neutral	0,42	neutral	0,5	neutral	0,41	2	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	0,02	low_impact	-1,93	0,64	0,8	11,61	14,07	N	0,36	N	0,83	disease_causing	0,72	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12934	12934	C	A	MI.20535	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	598	200	Q	K	Caa/Aaa	3,17	1	0	probably_damaging	1	neutral	0,3	neutral	4,71	neutral	-0,71	deleterious	-3,91	low_impact	1,92	neutral	0,7	damaging	0,13	deleterious	4,04	23,7	0,55	0,6	disease	0,59	disease	0,69	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,03	medium_impact	0,55	0,6	0,8	11,61	14,07	N	0,41	N	0,81	disease_causing	0,84	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12935	12935	A	C	MI.20536	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	599	200	Q	P	cAa/cCa	2,71	1	0	probably_damaging	1	neutral	0,22	neutral	4,6	neutral	-2,9	deleterious	-5,88	low_impact	1,02	neutral	0,67	damaging	0,12	deleterious	3,07	22,5	0,13	0,4	disease	0,84	disease	0,81	disease	0,81	disease	0,84	7	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,07	medium_impact	-0,27	0,44	0,8	11,61	14,07	N	0,34	N	0,94	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12935	12935	A	G	MI.20537	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	599	200	Q	R	cAa/cGa	2,71	1	0	probably_damaging	1	neutral	0,35	neutral	4,64	neutral	-1,09	deleterious	-3,88	low_impact	1,69	neutral	0,66	damaging	0,12	deleterious	3,15	22,6	0,56	0,6	disease	0,69	disease	0,7	disease	0,8	disease	0,78	6	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,82	low_impact	-3,6	medium_impact	0,08	medium_impact	0,34	0,51	0,8	11,61	14,07	N	0,38	N	0,7	disease_causing	0,89	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12935	12935	A	T	MI.20538	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	599	200	Q	L	cAa/cTa	2,71	1	0	probably_damaging	1	neutral	0,68	neutral	4,67	neutral	-0,75	deleterious	-6,5	neutral_impact	0,74	neutral	0,72	damaging	0,12	deleterious	3,5	23,1	0,32	0,5	disease	0,68	disease	0,71	disease	0,67	disease	0,63	3	deleterious	1	neutral	0,34	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	0,41	medium_impact	-0,53	0,28	0,8	11,61	14,07	N	0,29	N	0,94	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12936	12936	A	C	MI.20539	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	600	200	Q	H	caA/caC	6,84	1	0	probably_damaging	1	neutral	0,54	neutral	4,59	neutral	-1,55	deleterious	-4,88	low_impact	1,3	neutral	0,75	neutral	0,56	deleterious	2,28	18,05	0,59	0,65	disease	0,82	disease	0,58	neutral	0,49	disease	0,57	1	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,8	low_impact	-3,6	medium_impact	0,27	medium_impact	-0,02	0,7	0,85	11,61	14,07	N	0,45	N	0,81	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5988	5988	C	G	MI.2054	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	85	29	L	V	Cta/Gta	0,59	0,98	0	benign	0	neutral	1	neutral	2,76	neutral	-0,53	neutral	0,73	neutral_impact	-0,34	neutral	0,79	neutral	0,97	neutral	-1,46	0	0,46	0,55	neutral	0,23	neutral	0,07	neutral	0,17	neutral	0,23	6	neutral	0	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,07	high_impact	1,86	low_impact	-1,41	0,73	0,9	13,45	58,16	N	0,43	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12936	12936	A	T	MI.20540	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	600	200	Q	H	caA/caT	6,84	1	0	probably_damaging	1	neutral	0,54	neutral	4,59	neutral	-1,55	deleterious	-4,88	low_impact	1,3	neutral	0,75	neutral	0,56	deleterious	2,38	18,67	0,59	0,65	disease	0,82	disease	0,58	neutral	0,49	disease	0,57	1	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,8	low_impact	-3,6	medium_impact	0,27	medium_impact	-0,02	0,7	0,85	11,61	14,07	N	0,46	N	0,81	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12937	12937	A	T	MI.20541	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	601	201	M	L	Ata/Tta	0,18	0,06	0	benign	0,16	neutral	0,89	neutral	4,94	neutral	2,43	neutral	0,28	neutral_impact	-1,08	neutral	0,84	neutral	0,95	deleterious	0,11	3,74	0,65	0,7	neutral	0,33	neutral	0,3	neutral	0,25	neutral	0,46	1	neutral	0,07	deleterious	0,87	neutral	-6	neutral	0,14	medium_impact	-0,06	medium_impact	0,73	low_impact	-2,19	0,63	0,8	19,07	18,66	N	0,31	N	0,1	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12937	12937	A	C	MI.20542	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	601	201	M	L	Ata/Cta	0,18	0,06	0	benign	0,16	neutral	0,89	neutral	4,94	neutral	2,43	neutral	0,28	neutral_impact	-1,08	neutral	0,84	neutral	0,95	deleterious	0,01	2,71	0,65	0,7	neutral	0,33	neutral	0,3	neutral	0,25	neutral	0,46	1	neutral	0,07	deleterious	0,87	neutral	-6	neutral	0,14	medium_impact	-0,06	medium_impact	0,73	low_impact	-2,19	0,63	0,8	19,07	18,66	N	0,31	N	0,1	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12937	12937	A	G	MI.20543	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	601	201	M	V	Ata/Gta	0,18	0,06	0	benign	0,02	neutral	0,63	neutral	4,72	neutral	1,05	neutral	0,2	neutral_impact	-0,12	neutral	0,79	neutral	0,8	neutral	-0,43	0,33	0,64	0,7	neutral	0,34	neutral	0,35	neutral	0,29	neutral	0,47	1	neutral	0,34	deleterious	0,81	neutral	-6	neutral	0,12	medium_impact	0,86	medium_impact	0,36	low_impact	-1,31	0,69	0,85	19,07	18,66	N	0,27	N	0,02	polymorphism	1	0	rs201612920	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12938	12938	T	C	MI.20544	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	602	201	M	T	aTa/aCa	0,41	0,06	0	possibly_damaging	0,56	neutral	0,5	neutral	4,65	neutral	0,19	deleterious	-2,73	neutral_impact	0,2	neutral	0,83	neutral	0,8	neutral	1,28	12,14	0,56	0,6	neutral	0,3	disease	0,57	neutral	0,48	neutral	0,48	1	neutral	0,55	deleterious	0,47	neutral	-3	neutral	0,33	medium_impact	-0,85	medium_impact	0,23	low_impact	-1,02	0,46	0,8	19,07	18,66	N	0,3	N	0,36	polymorphism	0,98	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12938	12938	T	A	MI.20545	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	602	201	M	K	aTa/aAa	0,41	0,06	0	possibly_damaging	0,86	neutral	0,36	neutral	4,59	neutral	-1,6	deleterious	-3,83	low_impact	1,59	neutral	0,75	neutral	0,47	deleterious	2,69	20,7	0,22	0,45	neutral	0,42	disease	0,69	disease	0,67	disease	0,73	5	neutral	0,86	neutral	0,25	neutral	-3	deleterious	0,49	low_impact	-1,5	medium_impact	0,1	medium_impact	0,25	0,48	0,8	19,07	18,66	N	0,33	N	0,84	polymorphism	0,88	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12939	12939	A	T	MI.20546	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	603	201	M	I	atA/atT	1,56	0,09	0	benign	0,32	neutral	0,59	neutral	4,86	neutral	2,02	neutral	0,92	neutral_impact	-1,8	neutral	0,82	neutral	0,97	neutral	-1,07	0,01	0,59	0,65	neutral	0,27	neutral	0,16	neutral	0,16	neutral	0,27	5	neutral	0,32	deleterious	0,64	neutral	-6	neutral	0,14	medium_impact	-0,44	medium_impact	0,32	low_impact	-2,85	0,7	0,85	19,07	18,66	N	0,38	N	0,06	polymorphism	0,88	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12939	12939	A	C	MI.20547	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	603	201	M	I	atA/atC	1,56	0,09	0	benign	0,32	neutral	0,59	neutral	4,86	neutral	2,02	neutral	0,92	neutral_impact	-1,8	neutral	0,82	neutral	0,97	neutral	-1,23	0,01	0,59	0,65	neutral	0,27	neutral	0,16	neutral	0,16	neutral	0,27	5	neutral	0,32	deleterious	0,64	neutral	-6	neutral	0,14	medium_impact	-0,44	medium_impact	0,32	low_impact	-2,85	0,7	0,85	19,07	18,66	N	0,39	N	0,06	polymorphism	0,88	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12940	12940	G	A	MI.20548	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	604	202	A	T	Gcc/Acc	-4,86	0	0,01	benign	0,01	neutral	0,39	neutral	4,61	neutral	-2,68	neutral	-0,1	neutral_impact	0,65	neutral	0,81	neutral	0,75	deleterious	2,25	17,85	0,57	0,65	neutral	0,41	neutral	0,29	neutral	0,26	neutral	0,46	1	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,15	medium_impact	1,15	medium_impact	0,13	medium_impact	-0,61	0,73	0,85	14,1	14,08	N	0,43	N	0,12	polymorphism	1	0,01	rs200106331	.	.	.	.	.	COSM488736	.	.	.	.	.	.	.	.
chrM	12940	12940	G	C	MI.20549	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	604	202	A	P	Gcc/Ccc	-4,86	0	0,01	benign	0,29	neutral	0,23	neutral	4,55	deleterious	-4,24	neutral	-1,81	low_impact	1,19	neutral	0,67	neutral	0,6	deleterious	2,01	16,25	0,25	0,45	disease	0,69	disease	0,72	disease	0,61	disease	0,7	4	neutral	0,72	deleterious	0,47	neutral	-6	deleterious	0,55	medium_impact	-0,38	medium_impact	-0,06	medium_impact	-0,12	0,71	0,85	14,1	14,08	N	0,29	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5988	5988	C	A	MI.2055	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	85	29	L	M	Cta/Ata	0,59	0,98	0	benign	0	neutral	0,08	neutral	2,55	neutral	-2,67	neutral	-0,16	low_impact	0,8	neutral	0,67	neutral	0,86	deleterious	0,43	6,84	0,32	0,55	neutral	0,35	neutral	0,37	neutral	0,26	neutral	0,47	1	neutral	0,92	deleterious	0,54	neutral	-6	neutral	0,15	high_impact	2,07	medium_impact	-0,4	medium_impact	-0,36	0,68	0,9	13,45	58,16	P	0,58	P	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12940	12940	G	T	MI.20550	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	604	202	A	S	Gcc/Tcc	-4,86	0	0,01	benign	0,01	neutral	0,41	neutral	4,65	neutral	-1,96	neutral	-0,2	neutral_impact	0,01	neutral	0,8	neutral	0,71	neutral	1,72	14,53	0,63	0,7	neutral	0,33	neutral	0,26	neutral	0,39	neutral	0,44	1	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,15	medium_impact	1,15	medium_impact	0,15	low_impact	-1,19	0,77	0,85	14,1	14,08	N	0,35	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12941	12941	C	G	MI.20551	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	605	202	A	G	gCc/gGc	0,18	0	0	benign	0,11	neutral	0,33	neutral	4,58	neutral	-2,23	neutral	-1,23	low_impact	1,34	neutral	0,81	neutral	0,64	deleterious	2,08	16,73	0,5	0,6	disease	0,62	neutral	0,28	neutral	0,39	disease	0,55	1	neutral	0,62	deleterious	0,61	neutral	-6	neutral	0,26	medium_impact	0,12	medium_impact	0,06	medium_impact	0,02	0,7	0,85	14,1	14,08	N	0,39	N	0,33	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12941	12941	C	A	MI.20552	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	605	202	A	D	gCc/gAc	0,18	0	0	benign	0,17	neutral	0,2	neutral	4,59	deleterious	-3,15	neutral	-1,28	low_impact	1,28	neutral	0,74	neutral	0,65	deleterious	2,76	21,2	0,39	0,5	disease	0,68	disease	0,63	disease	0,58	disease	0,72	4	neutral	0,77	deleterious	0,52	neutral	-6	deleterious	0,44	medium_impact	-0,09	medium_impact	-0,1	medium_impact	-0,03	0,54	0,8	14,1	14,08	N	0,35	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12941	12941	C	T	MI.20553	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	605	202	A	V	gCc/gTc	0,18	0	0	benign	0	neutral	0,51	neutral	4,66	deleterious	-3,3	neutral	1,01	neutral_impact	0,32	neutral	0,86	neutral	0,78	deleterious	2,46	19,22	0,57	0,65	neutral	0,25	neutral	0,32	neutral	0,45	neutral	0,44	1	neutral	0,49	deleterious	0,76	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,24	medium_impact	-0,91	0,77	0,85	14,1	14,08	N	0,32	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12943	12943	C	A	MI.20554	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	607	203	L	I	Ctt/Att	-4,63	0	0	benign	0,01	neutral	0,41	neutral	4,51	neutral	-2,7	neutral	0,02	neutral_impact	-0,08	neutral	0,87	neutral	0,99	neutral	1,62	13,96	0,65	0,7	disease	0,55	neutral	0,09	neutral	0,16	neutral	0,33	3	neutral	0,58	deleterious	0,7	neutral	-6	deleterious	0,65	medium_impact	1,15	medium_impact	0,15	low_impact	-1,28	0,55	0,8	18,74	11,88	N	0,52	P	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12943	12943	C	G	MI.20555	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	607	203	L	V	Ctt/Gtt	-4,63	0	0	benign	0,04	neutral	0,51	neutral	4,54	neutral	-1,39	neutral	-0,32	neutral_impact	0,74	neutral	0,85	neutral	0,93	deleterious	2,09	16,82	0,73	0,75	neutral	0,5	neutral	0,12	neutral	0,18	neutral	0,27	5	neutral	0,44	deleterious	0,74	neutral	-6	deleterious	0,64	medium_impact	0,57	medium_impact	0,24	medium_impact	-0,53	0,59	0,8	18,74	11,88	N	0,42	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12943	12943	C	T	MI.20556	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	607	203	L	F	Ctt/Ttt	-4,63	0	0	possibly_damaging	0,68	neutral	0,72	neutral	4,51	neutral	-2,48	neutral	-1,36	neutral_impact	0,48	neutral	0,82	neutral	0,95	deleterious	2,18	17,41	0,79	0,8	disease	0,63	neutral	0,2	neutral	0,18	neutral	0,41	2	neutral	0,61	deleterious	0,52	neutral	-3	deleterious	0,68	low_impact	-1,06	medium_impact	0,46	medium_impact	-0,76	0,5	0,8	18,74	11,88	N	0,32	N	0,13	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12944	12944	T	A	MI.20557	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	608	203	L	H	cTt/cAt	-6,47	0	0	probably_damaging	0,95	neutral	0,55	neutral	4,51	neutral	-2,61	deleterious	-3,39	low_impact	1,37	neutral	0,76	neutral	0,76	deleterious	2,96	22,1	0,38	0,5	disease	0,78	neutral	0,4	neutral	0,28	disease	0,56	1	neutral	0,95	neutral	0,3	neutral	-2	deleterious	0,74	low_impact	-1,96	medium_impact	0,28	medium_impact	0,05	0,57	0,8	18,74	11,88	N	0,26	N	0,49	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12944	12944	T	C	MI.20558	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	608	203	L	P	cTt/cCt	-6,47	0	0	possibly_damaging	0,8	neutral	0,22	neutral	4,5	neutral	-2,89	deleterious	-3,46	low_impact	0,88	neutral	0,79	neutral	0,76	deleterious	3,72	23,3	0,27	0,45	disease	0,8	disease	0,66	disease	0,57	disease	0,68	4	neutral	0,87	neutral	0,21	neutral	-3	deleterious	0,81	low_impact	-1,32	medium_impact	-0,07	medium_impact	-0,4	0,46	0,8	18,74	11,88	N	0,28	N	0,75	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12944	12944	T	G	MI.20559	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	608	203	L	R	cTt/cGt	-6,47	0	0	possibly_damaging	0,74	neutral	0,35	neutral	4,57	neutral	-0,98	deleterious	-3	low_impact	1,64	neutral	0,72	neutral	0,5	deleterious	4,12	23,8	0,35	0,5	disease	0,68	disease	0,59	neutral	0,5	neutral	0,49	0	neutral	0,78	neutral	0,31	neutral	-3	deleterious	0,79	low_impact	-1,18	medium_impact	0,08	medium_impact	0,3	0,61	0,8	18,74	11,88	N	0,28	N	0,45	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5989	5989	T	A	MI.2056	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	86	29	L	Q	cTa/cAa	1,75	0,98	0	benign	0,1	deleterious	0	neutral	2,51	deleterious	-3,47	neutral	-1,92	high_impact	3,66	neutral	0,63	neutral	0,62	deleterious	2,04	16,49	0,18	0,55	disease	0,7	disease	0,7	disease	0,53	disease	0,64	3	deleterious	1	neutral	0,45	deleterious	2	neutral	0,28	medium_impact	0,14	low_impact	-1,48	high_impact	2,28	0,75	0,9	13,45	58,16	N	0,51	P	0,47	polymorphism	0,96	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12946	12946	C	G	MI.20560	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	610	204	L	V	Cta/Gta	-13,81	0	0	probably_damaging	1	neutral	0,53	neutral	4,57	neutral	-1,69	neutral	-0,84	medium_impact	2,14	neutral	0,82	neutral	0,45	deleterious	2,31	18,23	0,68	0,7	neutral	0,44	neutral	0,21	neutral	0,38	neutral	0,39	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,67	low_impact	-3,6	medium_impact	0,26	medium_impact	0,75	0,48	0,8	19,4	14,75	N	0,28	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12946	12946	C	A	MI.20561	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	610	204	L	M	Cta/Ata	-13,81	0	0	probably_damaging	1	neutral	0,24	neutral	4,53	neutral	-2,64	neutral	-0,28	low_impact	1,53	neutral	0,83	neutral	0,85	deleterious	2,55	19,79	0,45	0,55	disease	0,63	neutral	0,17	neutral	0,19	neutral	0,41	2	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	-0,04	medium_impact	0,2	0,73	0,85	19,4	14,75	N	0,53	P	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12947	12947	T	G	MI.20562	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	611	204	L	R	cTa/cGa	-3,26	0	0	probably_damaging	1	neutral	0,4	neutral	4,55	deleterious	-3,39	deleterious	-2,53	medium_impact	1,96	neutral	0,7	damaging	0,11	deleterious	4,03	23,7	0,48	0,55	neutral	0,27	disease	0,68	disease	0,58	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,14	medium_impact	0,59	0,57	0,8	19,4	14,75	N	0,21	N	0,6	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12947	12947	T	C	MI.20563	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	611	204	L	P	cTa/cCa	-3,26	0	0	probably_damaging	1	neutral	0,27	neutral	4,51	deleterious	-3,97	deleterious	-3,04	medium_impact	2,63	neutral	0,71	neutral	0,35	deleterious	3,79	23,4	0,52	0,6	disease	0,74	disease	0,66	disease	0,69	disease	0,55	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	-0,01	medium_impact	1,2	0,44	0,8	19,4	14,75	N	0,26	N	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12947	12947	T	A	MI.20564	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	611	204	L	Q	cTa/cAa	-3,26	0	0	probably_damaging	1	neutral	0,39	neutral	4,52	deleterious	-3,65	neutral	-2,31	low_impact	0,94	neutral	0,83	neutral	0,32	deleterious	3,92	23,5	0,46	0,55	disease	0,6	neutral	0,45	neutral	0,27	disease	0,58	2	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	0,13	medium_impact	-0,34	0,61	0,8	19,4	14,75	N	0,29	N	0,57	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12949	12949	A	C	MI.20565	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	613	205	N	H	Aac/Cac	-6,24	0	0	probably_damaging	0,94	neutral	0,55	neutral	4,47	neutral	-2,81	neutral	-1,49	low_impact	1,28	neutral	0,81	neutral	0,97	deleterious	1,87	15,42	0,84	0,85	disease	0,64	neutral	0,27	neutral	0,31	disease	0,55	1	neutral	0,93	neutral	0,31	neutral	-2	deleterious	0,64	low_impact	-1,88	medium_impact	0,28	medium_impact	-0,03	0,34	0,8	10,45	11,95	N	0,31	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12949	12949	A	G	MI.20566	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	613	205	N	D	Aac/Gac	-6,24	0	0	benign	0,03	neutral	0,23	neutral	4,55	neutral	-0,91	neutral	-1,59	neutral_impact	0,58	neutral	0,87	neutral	0,94	deleterious	0,68	8,67	0,9	0,9	neutral	0,45	neutral	0,22	neutral	0,26	neutral	0,37	3	neutral	0,76	deleterious	0,6	neutral	-6	neutral	0,41	medium_impact	0,69	medium_impact	-0,06	medium_impact	-0,67	0,28	0,8	10,45	11,95	N	0,5	N	0,58	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12949	12949	A	T	MI.20567	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	613	205	N	Y	Aac/Tac	-6,24	0	0	probably_damaging	0,92	neutral	1	neutral	4,45	deleterious	-3,52	deleterious	-3,25	low_impact	0,86	neutral	0,83	neutral	0,75	deleterious	3,56	23,1	0,67	0,7	disease	0,73	neutral	0,32	neutral	0,3	disease	0,63	3	neutral	0,92	deleterious	0,54	neutral	-2	deleterious	0,68	low_impact	-1,75	high_impact	1,89	medium_impact	-0,42	0,41	0,8	10,45	11,95	N	0,22	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12950	12950	A	C	MI.20568	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	614	205	N	T	aAc/aCc	-3,26	0	0,03	possibly_damaging	0,52	neutral	0,43	neutral	4,5	neutral	-1,68	neutral	-2,4	neutral_impact	-0,2	neutral	0,87	neutral	0,98	deleterious	0,26	5,33	0,77	0,8	neutral	0,22	neutral	0,16	neutral	0,2	neutral	0,29	4	neutral	0,57	neutral	0,46	neutral	-3	neutral	0,32	medium_impact	-0,78	medium_impact	0,17	low_impact	-1,39	0,34	0,8	10,45	11,95	N	0,41	N	0,13	polymorphism	1	0,05	rs201361958	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12950	12950	A	G	MI.20569	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	614	205	N	S	aAc/aGc	-3,26	0	0,03	benign	0,08	neutral	0,45	neutral	4,61	neutral	-0,25	neutral	-1,79	neutral_impact	-0,28	neutral	0,83	neutral	0,96	neutral	-1,66	0	0,73	0,75	neutral	0,4	neutral	0,07	neutral	0,17	neutral	0,23	6	neutral	0,49	deleterious	0,69	neutral	-6	neutral	0,11	medium_impact	0,26	medium_impact	0,18	low_impact	-1,46	0,15	0,8	10,45	11,95	N	0,35	N	0,01	polymorphism	1	0,02	rs201361958	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5989	5989	T	G	MI.2057	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	86	29	L	R	cTa/cGa	1,75	0,98	0	benign	0,08	deleterious	0	neutral	2,56	deleterious	-3,42	neutral	-2,25	high_impact	3,66	damaging	0,52	neutral	0,51	deleterious	2,11	16,94	0,18	0,55	neutral	0,45	disease	0,88	disease	0,66	disease	0,82	6	deleterious	1	neutral	0,46	deleterious	2	neutral	0,3	medium_impact	0,24	low_impact	-1,48	high_impact	2,28	0,76	0,9	13,45	58,16	N	0,53	P	0,55	polymorphism	0,95	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12950	12950	A	T	MI.20570	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	614	205	N	I	aAc/aTc	-3,26	0	0,03	possibly_damaging	0,89	neutral	0,41	neutral	4,51	neutral	-1,54	deleterious	-4,52	neutral_impact	0,57	neutral	0,82	neutral	0,63	deleterious	3,61	23,2	0,66	0,7	neutral	0,47	neutral	0,45	neutral	0,38	neutral	0,48	0	neutral	0,89	neutral	0,26	neutral	-3	deleterious	0,61	low_impact	-1,61	medium_impact	0,15	medium_impact	-0,68	0,33	0,8	10,45	11,95	N	0,28	N	0,81	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12951	12951	C	A	MI.20571	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	615	205	N	K	aaC/aaA	-0,5	0	0	possibly_damaging	0,52	neutral	0,33	neutral	4,55	neutral	-0,94	deleterious	-2,55	low_impact	1,52	neutral	0,85	neutral	0,87	neutral	1,48	13,22	0,86	0,9	neutral	0,24	neutral	0,33	neutral	0,44	neutral	0,45	1	neutral	0,66	neutral	0,41	neutral	-3	neutral	0,41	medium_impact	-0,78	medium_impact	0,06	medium_impact	0,19	0,51	0,8	10,45	11,95	N	0,37	N	0,54	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12951	12951	C	G	MI.20572	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	615	205	N	K	aaC/aaG	-0,5	0	0	possibly_damaging	0,52	neutral	0,33	neutral	4,55	neutral	-0,94	deleterious	-2,55	low_impact	1,52	neutral	0,85	neutral	0,87	neutral	1	10,68	0,86	0,9	neutral	0,24	neutral	0,33	neutral	0,44	neutral	0,45	1	neutral	0,66	neutral	0,41	neutral	-3	neutral	0,41	medium_impact	-0,78	medium_impact	0,06	medium_impact	0,19	0,51	0,8	10,45	11,95	N	0,37	N	0,54	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12952	12952	G	A	MI.20573	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	616	206	A	T	Gct/Act	-11,74	0	0	benign	0	neutral	0,42	neutral	4,66	neutral	0,32	neutral	0,82	neutral_impact	-0,64	neutral	0,9	neutral	0,94	deleterious	0,56	7,88	0,7	0,75	neutral	0,39	neutral	0,15	neutral	0,24	neutral	0,29	4	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,11	high_impact	2,1	medium_impact	0,16	low_impact	-1,79	0,68	0,85	35,49	20,15	N	0,47	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12952	12952	G	C	MI.20574	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	616	206	A	P	Gct/Cct	-11,74	0	0	benign	0	neutral	0,23	neutral	4,58	neutral	-1,81	neutral	1,4	neutral_impact	-0,76	neutral	0,9	neutral	0,97	deleterious	0,5	7,44	0,43	0,55	disease	0,51	disease	0,54	neutral	0,26	neutral	0,45	1	neutral	0,77	deleterious	0,62	neutral	-6	deleterious	0,48	high_impact	2,1	medium_impact	-0,06	low_impact	-1,9	0,58	0,8	35,49	20,15	N	0,38	N	0,13	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12952	12952	G	T	MI.20575	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	616	206	A	S	Gct/Tct	-11,74	0	0	benign	0,01	neutral	0,45	neutral	4,75	neutral	1,24	neutral	1,06	neutral_impact	-0,52	neutral	0,91	neutral	0,92	deleterious	0,07	3,29	0,54	0,6	neutral	0,46	neutral	0,17	neutral	0,23	neutral	0,29	4	neutral	0,54	deleterious	0,72	neutral	-6	neutral	0,14	medium_impact	1,15	medium_impact	0,18	low_impact	-1,68	0,58	0,8	35,49	20,15	N	0,41	N	0,1	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12953	12953	C	A	MI.20576	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	617	206	A	D	gCt/gAt	-3,03	0	0	benign	0,11	neutral	0,23	neutral	4,62	neutral	-0,56	neutral	0,98	neutral_impact	-0,36	neutral	0,84	neutral	0,73	neutral	1,15	11,47	0,47	0,55	disease	0,63	neutral	0,45	neutral	0,49	disease	0,6	2	neutral	0,74	deleterious	0,56	neutral	-6	neutral	0,27	medium_impact	0,12	medium_impact	-0,06	low_impact	-1,53	0,53	0,8	35,49	20,15	N	0,38	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12953	12953	C	G	MI.20577	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	617	206	A	G	gCt/gGt	-3,03	0	0	benign	0,07	neutral	0,35	neutral	4,62	neutral	-0,59	neutral	-0,52	neutral_impact	-0,36	neutral	0,84	neutral	0,78	deleterious	0,84	9,71	0,6	0,65	neutral	0,38	neutral	0,17	neutral	0,38	neutral	0,3	4	neutral	0,61	deleterious	0,64	neutral	-6	neutral	0,16	medium_impact	0,32	medium_impact	0,08	low_impact	-1,53	0,74	0,85	35,49	20,15	N	0,39	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12953	12953	C	T	MI.20578	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	617	206	A	V	gCt/gTt	-3,03	0	0	benign	0,11	neutral	0,52	neutral	4,6	neutral	-0,89	neutral	-0,88	low_impact	0,99	neutral	0,88	neutral	0,77	neutral	1,32	12,36	0,62	0,65	neutral	0,39	neutral	0,23	neutral	0,42	neutral	0,44	1	neutral	0,39	deleterious	0,71	neutral	-6	neutral	0,2	medium_impact	0,12	medium_impact	0,25	medium_impact	-0,3	0,64	0,8	35,49	20,15	N	0,35	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12955	12955	A	G	MI.20579	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	619	207	N	D	Aat/Gat	-4,63	0	0	benign	0,02	neutral	0,23	neutral	4,48	neutral	-0,56	neutral	-0,88	neutral_impact	0,64	neutral	0,85	neutral	0,97	deleterious	0,42	6,8	0,74	0,75	disease	0,57	neutral	0,19	neutral	0,47	neutral	0,42	2	neutral	0,76	deleterious	0,61	neutral	-6	deleterious	0,47	medium_impact	0,86	medium_impact	-0,06	medium_impact	-0,62	0,33	0,8	16,58	10,52	N	0,43	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5989	5989	T	C	MI.2058	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	86	29	L	P	cTa/cCa	1,75	0,98	0	benign	0,1	deleterious	0	neutral	2,51	deleterious	-4,16	neutral	-2,06	high_impact	3,66	damaging	0,46	neutral	0,45	deleterious	1,88	15,45	0,14	0,55	disease	0,75	disease	0,9	disease	0,68	disease	0,81	6	deleterious	1	neutral	0,45	deleterious	2	neutral	0,36	medium_impact	0,14	low_impact	-1,48	high_impact	2,28	0,59	0,9	13,45	58,16	P	0,55	P	0,66	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12955	12955	A	T	MI.20580	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	619	207	N	Y	Aat/Tat	-4,63	0	0	benign	0,03	neutral	1	neutral	4,5	deleterious	-3,28	deleterious	-3,46	low_impact	1,68	neutral	0,84	neutral	0,73	deleterious	3,59	23,2	0,48	0,55	disease	0,85	neutral	0,48	disease	0,54	disease	0,67	3	neutral	0,03	deleterious	0,99	neutral	-6	deleterious	0,73	medium_impact	0,69	high_impact	1,89	medium_impact	0,33	0,41	0,8	16,58	10,52	N	0,21	N	0,93	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12955	12955	A	C	MI.20581	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	619	207	N	H	Aat/Cat	-4,63	0	0	benign	0,04	neutral	0,55	neutral	4,47	neutral	-1,42	neutral	-1,77	low_impact	1,5	neutral	0,84	neutral	0,82	deleterious	1,83	15,16	0,68	0,7	disease	0,77	neutral	0,43	neutral	0,41	disease	0,65	3	neutral	0,4	deleterious	0,76	neutral	-6	deleterious	0,69	medium_impact	0,57	medium_impact	0,28	medium_impact	0,17	0,41	0,8	16,58	10,52	N	0,26	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12956	12956	A	C	MI.20582	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	620	207	N	T	aAt/aCt	-2,57	0	0	benign	0,03	neutral	0,41	neutral	4,59	neutral	-0,81	neutral	-2,04	neutral_impact	0,57	neutral	0,86	neutral	0,96	deleterious	0,48	7,31	0,54	0,6	disease	0,63	neutral	0,23	neutral	0,28	disease	0,54	1	neutral	0,56	deleterious	0,69	neutral	-6	deleterious	0,44	medium_impact	0,69	medium_impact	0,15	medium_impact	-0,68	0,32	0,8	16,58	10,52	N	0,34	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12956	12956	A	G	MI.20583	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	620	207	N	S	aAt/aGt	-2,57	0	0	benign	0,03	neutral	0,44	neutral	4,57	neutral	0,04	neutral	-1,29	low_impact	1,23	neutral	0,91	neutral	0,98	deleterious	0,11	3,71	0,7	0,75	neutral	0,28	neutral	0,27	neutral	0,29	neutral	0,44	1	neutral	0,53	deleterious	0,71	neutral	-6	neutral	0,13	medium_impact	0,69	medium_impact	0,18	medium_impact	-0,08	0,09	0,8	16,58	10,52	N	0,41	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12956	12956	A	T	MI.20584	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	620	207	N	I	aAt/aTt	-2,57	0	0	possibly_damaging	0,59	neutral	0,41	neutral	4,56	deleterious	-3,19	deleterious	-4,17	low_impact	1,88	neutral	0,87	neutral	0,79	deleterious	3,79	23,4	0,48	0,55	disease	0,81	disease	0,55	neutral	0,46	disease	0,55	1	neutral	0,63	neutral	0,41	neutral	-3	deleterious	0,7	medium_impact	-0,9	medium_impact	0,15	medium_impact	0,51	0,37	0,8	16,58	10,52	N	0,35	N	0,9	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12957	12957	T	A	MI.20585	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	621	207	N	K	aaT/aaA	0,64	0	0,01	benign	0,27	neutral	0,31	neutral	4,51	neutral	-1,29	neutral	-0,14	low_impact	0,9	neutral	0,86	neutral	0,93	neutral	1,45	13,02	0,77	0,8	neutral	0,49	neutral	0,43	neutral	0,32	neutral	0,42	2	neutral	0,63	deleterious	0,52	neutral	-6	deleterious	0,52	medium_impact	-0,34	medium_impact	0,04	medium_impact	-0,38	0,41	0,8	16,58	10,52	N	0,46	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12957	12957	T	G	MI.20586	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	621	207	N	K	aaT/aaG	0,64	0	0,01	benign	0,27	neutral	0,31	neutral	4,51	neutral	-1,29	neutral	-0,14	low_impact	0,9	neutral	0,86	neutral	0,93	neutral	1,13	11,39	0,77	0,8	neutral	0,49	neutral	0,43	neutral	0,32	neutral	0,42	2	neutral	0,63	deleterious	0,52	neutral	-6	deleterious	0,52	medium_impact	-0,34	medium_impact	0,04	medium_impact	-0,38	0,41	0,8	16,58	10,52	N	0,46	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12958	12958	C	A	MI.20587	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	622	208	P	T	Cca/Aca	-4,86	0	0	benign	0,02	neutral	0,7	neutral	4,71	neutral	-2,54	neutral	0,83	neutral_impact	0,41	neutral	0,87	neutral	0,97	deleterious	0,1	3,58	0,56	0,6	neutral	0,26	neutral	0,11	neutral	0,19	neutral	0,29	4	neutral	0,27	deleterious	0,84	neutral	-6	neutral	0,08	medium_impact	0,86	medium_impact	0,44	medium_impact	-0,83	0,78	0,85	26,53	19,06	N	0,37	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12958	12958	C	T	MI.20588	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	622	208	P	S	Cca/Tca	-4,86	0	0	benign	0,02	neutral	0,83	neutral	4,7	neutral	-2,38	neutral	0,57	neutral_impact	0,3	neutral	0,89	neutral	0,95	deleterious	0,08	3,42	0,54	0,6	neutral	0,33	neutral	0,15	neutral	0,18	neutral	0,3	4	neutral	0,13	deleterious	0,91	neutral	-6	neutral	0,11	medium_impact	0,86	medium_impact	0,61	medium_impact	-0,93	0,29	0,8	26,53	19,06	N	0,35	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12958	12958	C	G	MI.20589	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	622	208	P	A	Cca/Gca	-4,86	0	0	benign	0,25	neutral	0,99	neutral	4,74	neutral	-1,82	neutral	-0,32	low_impact	1,25	neutral	0,85	neutral	0,83	neutral	-0,64	0,1	0,48	0,55	neutral	0,32	neutral	0,1	neutral	0,34	neutral	0,3	4	neutral	0,23	deleterious	0,87	neutral	-6	neutral	0,26	medium_impact	-0,29	medium_impact	1,33	medium_impact	-0,06	0,8	0,85	26,53	19,06	N	0,27	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5991	5991	G	C	MI.2059	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	88	30	G	R	Ggc/Cgc	-8,66	0	0	probably_damaging	1	deleterious	0	neutral	2,2	deleterious	-5,45	deleterious	-4,19	high_impact	4,55	neutral	0,63	damaging	0,08	deleterious	3,69	23,3	0,08	0,55	disease	0,89	disease	0,9	disease	0,8	disease	0,89	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,1	0,72	0,9	2,14	8,62	N	0,45	N	0,95	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12959	12959	C	G	MI.20590	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	623	208	P	R	cCa/cGa	-1,65	0	0	possibly_damaging	0,57	neutral	0,6	neutral	4,66	deleterious	-3,3	neutral	-0,67	medium_impact	1,99	neutral	0,83	neutral	0,49	neutral	1,64	14,06	0,4	0,5	neutral	0,28	neutral	0,4	disease	0,6	neutral	0,46	1	neutral	0,51	deleterious	0,52	NA	0	deleterious	0,53	medium_impact	-0,86	medium_impact	0,33	medium_impact	0,62	0,7	0,85	26,53	19,06	N	0,24	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12959	12959	C	A	MI.20591	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	623	208	P	Q	cCa/cAa	-1,65	0	0	possibly_damaging	0,75	neutral	0,59	neutral	4,69	neutral	-2,77	neutral	-0,17	low_impact	1,18	neutral	0,85	neutral	0,76	deleterious	2,21	17,59	0,32	0,5	neutral	0,26	neutral	0,26	neutral	0,28	neutral	0,43	1	neutral	0,71	neutral	0,42	neutral	-3	deleterious	0,52	low_impact	-1,2	medium_impact	0,32	medium_impact	-0,13	0,62	0,8	26,53	19,06	N	0,29	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12959	12959	C	T	MI.20592	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	623	208	P	L	cCa/cTa	-1,65	0	0	benign	0,02	neutral	0,92	neutral	4,75	neutral	-2,75	neutral	-0,46	neutral_impact	-0,32	neutral	0,8	neutral	0,95	deleterious	0,49	7,34	0,43	0,55	neutral	0,39	neutral	0,24	neutral	0,42	neutral	0,43	1	neutral	0,04	deleterious	0,95	neutral	-6	neutral	0,35	medium_impact	0,86	medium_impact	0,82	low_impact	-1,5	0,74	0,85	26,53	19,06	N	0,24	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12961	12961	A	C	MI.20593	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	625	209	S	R	Agc/Cgc	-5,78	0	0	benign	0,26	neutral	0,34	neutral	4,62	neutral	-0,44	neutral	-1,88	low_impact	1,36	neutral	0,73	neutral	0,45	deleterious	2,04	16,46	0,39	0,5	disease	0,66	disease	0,69	disease	0,63	disease	0,72	4	neutral	0,59	deleterious	0,54	neutral	-6	deleterious	0,45	medium_impact	-0,32	medium_impact	0,07	medium_impact	0,04	0,75	0,85	21,39	17,32	N	0,27	N	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12961	12961	A	G	MI.20594	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	625	209	S	G	Agc/Ggc	-5,78	0	0	benign	0,18	neutral	0,34	neutral	4,58	neutral	-1,72	neutral	-2,09	neutral_impact	0,5	neutral	0,78	neutral	0,62	neutral	1,6	13,83	0,56	0,6	disease	0,74	neutral	0,24	neutral	0,44	disease	0,58	2	neutral	0,59	deleterious	0,58	neutral	-6	neutral	0,2	medium_impact	-0,12	medium_impact	0,07	medium_impact	-0,75	0,62	0,8	21,39	17,32	N	0,32	N	0,22	polymorphism	1	0,02	rs386829171	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12961	12961	A	T	MI.20595	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	625	209	S	C	Agc/Tgc	-5,78	0	0	possibly_damaging	0,89	neutral	0,19	neutral	4,59	neutral	-1,4	deleterious	-2,77	low_impact	1,86	neutral	0,72	neutral	0,39	deleterious	3,3	22,9	0,5	0,6	disease	0,9	disease	0,54	neutral	0,5	disease	0,65	3	neutral	0,93	neutral	0,15	neutral	-3	deleterious	0,69	low_impact	-1,61	medium_impact	-0,12	medium_impact	0,5	0,66	0,8	21,39	17,32	N	0,29	N	0,59	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12962	12962	G	T	MI.20596	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	626	209	S	I	aGc/aTc	-2,57	0	0	possibly_damaging	0,62	neutral	0,43	neutral	4,76	neutral	1,2	neutral	-2,41	neutral_impact	0,7	neutral	0,84	neutral	0,73	deleterious	3,59	23,2	0,58	0,65	neutral	0,47	disease	0,58	neutral	0,5	neutral	0,47	1	neutral	0,64	neutral	0,41	neutral	-3	deleterious	0,48	medium_impact	-0,95	medium_impact	0,17	medium_impact	-0,56	0,73	0,85	21,39	17,32	N	0,25	N	0,6	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12962	12962	G	A	MI.20597	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	626	209	S	N	aGc/aAc	-2,57	0	0	benign	0,01	neutral	0,37	neutral	4,62	neutral	-0,44	neutral	0,78	neutral_impact	-0,2	neutral	0,86	neutral	0,98	neutral	-0,54	0,18	0,78	0,8	disease	0,57	neutral	0,26	neutral	0,25	disease	0,55	1	neutral	0,62	deleterious	0,68	neutral	-6	neutral	0,16	medium_impact	1,15	medium_impact	0,11	low_impact	-1,39	0,55	0,8	21,39	17,32	N	0,35	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12962	12962	G	C	MI.20598	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	626	209	S	T	aGc/aCc	-2,57	0	0	benign	0,18	neutral	0,59	neutral	4,64	neutral	-0,04	neutral	-0,19	neutral_impact	-0,16	neutral	0,85	neutral	0,98	deleterious	0	2,63	0,48	0,55	neutral	0,4	neutral	0,14	neutral	0,22	neutral	0,28	4	neutral	0,3	deleterious	0,71	neutral	-6	neutral	0,23	medium_impact	-0,12	medium_impact	0,32	low_impact	-1,35	0,75	0,85	21,39	17,32	N	0,33	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12964	12964	C	A	MI.20599	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	628	210	L	I	Ctc/Atc	-3,49	0	0	benign	0,18	neutral	0,49	neutral	4,51	neutral	-1,62	neutral	0,01	neutral_impact	0,58	neutral	0,86	neutral	0,97	deleterious	0,89	9,98	0,56	0,6	neutral	0,5	neutral	0,24	neutral	0,2	neutral	0,31	4	neutral	0,41	deleterious	0,66	neutral	-6	neutral	0,35	medium_impact	-0,12	medium_impact	0,22	medium_impact	-0,67	0,73	0,85	26,2	20,78	N	0,44	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8623	8623	A	T	MI.206	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	97	33	T	S	Acc/Tcc	-15,14	0	0	benign	0,07	neutral	1	neutral	4,3	neutral	0,09	neutral	-1,2	neutral_impact	-0,01	neutral	0,93	neutral	0,96	neutral	-0,2	1,12	0,6	0,7	neutral	0,28	neutral	0,17	neutral	0,42	neutral	0,26	5	neutral	0,07	deleterious	0,97	neutral	-6	neutral	0,14	medium_impact	0,31	high_impact	1,98	low_impact	-1,11	0,6	0,9	19,47	19,69	N	0,35	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5991	5991	G	A	MI.2060	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	88	30	G	S	Ggc/Agc	-8,66	0	0	probably_damaging	1	deleterious	0	neutral	2,27	deleterious	-3,45	deleterious	-3,07	high_impact	4,75	damaging	0,58	damaging	0,11	deleterious	3,98	23,6	0,25	0,55	disease	0,82	disease	0,83	disease	0,68	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,71	0,9	2,14	8,62	P	0,63	P	0,73	disease_causing	0,99	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12964	12964	C	G	MI.20600	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	628	210	L	V	Ctc/Gtc	-3,49	0	0	benign	0,02	neutral	0,54	neutral	4,51	neutral	-1,75	neutral	-0,12	neutral_impact	0,64	neutral	0,83	neutral	0,82	deleterious	0,51	7,48	0,61	0,65	neutral	0,45	neutral	0,28	disease	0,55	neutral	0,48	0	neutral	0,44	deleterious	0,76	neutral	-6	neutral	0,39	medium_impact	0,86	medium_impact	0,27	medium_impact	-0,62	0,55	0,8	26,2	20,78	N	0,3	N	0,37	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12964	12964	C	T	MI.20601	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	628	210	L	F	Ctc/Ttc	-3,49	0	0	benign	0,02	neutral	0,72	neutral	4,47	neutral	-2,49	neutral	-1,22	low_impact	1,5	neutral	0,85	neutral	0,78	deleterious	0,65	8,52	0,59	0,65	disease	0,64	neutral	0,41	neutral	0,29	disease	0,61	2	neutral	0,24	deleterious	0,85	neutral	-6	neutral	0,16	medium_impact	0,86	medium_impact	0,46	medium_impact	0,17	0,68	0,85	26,2	20,78	N	0,27	N	0,2	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12965	12965	T	A	MI.20602	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	629	210	L	H	cTc/cAc	-3,03	0	0	probably_damaging	0,93	neutral	0,58	neutral	4,43	deleterious	-5,08	neutral	-1,75	medium_impact	2,58	neutral	0,77	neutral	0,56	deleterious	2,82	21,5	0,41	0,5	disease	0,57	disease	0,66	disease	0,67	disease	0,7	4	neutral	0,92	neutral	0,33	deleterious	1	deleterious	0,7	low_impact	-1,81	medium_impact	0,31	medium_impact	1,15	0,5	0,8	26,2	20,78	N	0,21	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12965	12965	T	C	MI.20603	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	629	210	L	P	cTc/cCc	-3,03	0	0	benign	0,03	neutral	0,34	neutral	4,47	deleterious	-5,11	neutral	-2,08	medium_impact	2,04	neutral	0,82	neutral	0,72	deleterious	2,65	20,5	0,25	0,45	disease	0,55	disease	0,79	disease	0,64	disease	0,7	4	neutral	0,64	deleterious	0,66	neutral	-3	deleterious	0,72	medium_impact	0,69	medium_impact	0,07	medium_impact	0,66	0,55	0,8	26,2	20,78	N	0,29	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12965	12965	T	G	MI.20604	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	629	210	L	R	cTc/cGc	-3,03	0	0	possibly_damaging	0,59	neutral	0,37	neutral	4,45	deleterious	-4,13	neutral	-1,62	medium_impact	3,13	neutral	0,68	neutral	0,47	deleterious	2,82	21,5	0,33	0,5	disease	0,6	disease	0,79	disease	0,72	disease	0,76	5	neutral	0,66	neutral	0,39	NA	0	deleterious	0,7	medium_impact	-0,9	medium_impact	0,11	medium_impact	1,66	0,58	0,8	26,2	20,78	N	0,3	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12967	12967	A	C	MI.20605	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	631	211	T	P	Acc/Ccc	-7,38	0	0	benign	0	neutral	0,26	neutral	4,53	deleterious	-3,02	neutral	-2,05	neutral_impact	-0,11	neutral	0,91	neutral	0,71	deleterious	2,03	16,42	0,31	0,45	disease	0,54	disease	0,81	neutral	0,49	disease	0,66	3	neutral	0,74	deleterious	0,63	neutral	-6	deleterious	0,61	high_impact	2,1	medium_impact	-0,02	low_impact	-1,3	0,41	0,8	13,76	11,27	N	0,3	N	0,48	polymorphism	1	0,02	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	12967	12967	A	G	MI.20606	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	631	211	T	A	Acc/Gcc	-7,38	0	0	benign	0,08	neutral	0,61	neutral	4,62	neutral	-0,36	neutral	-0,36	neutral_impact	0,11	neutral	0,86	neutral	0,87	deleterious	0,08	3,43	0,6	0,65	neutral	0,43	neutral	0,34	disease	0,55	neutral	0,49	0	neutral	0,3	deleterious	0,77	neutral	-6	neutral	0,19	medium_impact	0,26	medium_impact	0,34	low_impact	-1,1	0,3	0,8	13,76	11,27	N	0,28	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12967	12967	A	T	MI.20607	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	631	211	T	S	Acc/Tcc	-7,38	0	0	benign	0,29	neutral	0,48	neutral	4,56	neutral	-1,46	neutral	-1,05	neutral_impact	0,36	neutral	0,77	neutral	0,71	neutral	1,51	13,34	0,54	0,6	neutral	0,45	neutral	0,42	disease	0,54	neutral	0,5	0	neutral	0,43	deleterious	0,6	neutral	-6	neutral	0,37	medium_impact	-0,38	medium_impact	0,21	medium_impact	-0,87	0,52	0,8	13,76	11,27	N	0,31	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12968	12968	C	A	MI.20608	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	632	211	T	N	aCc/aAc	-5,55	0	0	possibly_damaging	0,48	neutral	0,35	neutral	4,54	neutral	-2,68	neutral	-1,64	neutral_impact	0,7	neutral	0,74	neutral	0,78	deleterious	3,23	22,8	0,38	0,5	disease	0,69	disease	0,64	disease	0,57	disease	0,67	3	neutral	0,62	neutral	0,44	neutral	-3	deleterious	0,59	medium_impact	-0,71	medium_impact	0,08	medium_impact	-0,56	0,68	0,85	13,76	11,27	N	0,29	N	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12968	12968	C	G	MI.20609	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	632	211	T	S	aCc/aGc	-5,55	0	0	benign	0,29	neutral	0,48	neutral	4,56	neutral	-1,46	neutral	-1,05	neutral_impact	0,36	neutral	0,77	neutral	0,71	neutral	1,75	14,69	0,54	0,6	neutral	0,45	neutral	0,42	disease	0,54	neutral	0,5	0	neutral	0,43	deleterious	0,6	neutral	-6	neutral	0,37	medium_impact	-0,38	medium_impact	0,21	medium_impact	-0,87	0,52	0,8	13,76	11,27	N	0,31	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5991	5991	G	T	MI.2061	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	88	30	G	C	Ggc/Tgc	-8,66	0	0	probably_damaging	1	deleterious	0	neutral	2,18	deleterious	-6,58	deleterious	-4,7	high_impact	5,1	neutral	0,6	damaging	0,08	deleterious	3,94	23,5	0,13	0,55	disease	0,96	disease	0,91	disease	0,7	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,61	0,51	0,9	2,14	8,62	P	0,6	P	0,98	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12968	12968	C	T	MI.20610	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	632	211	T	I	aCc/aTc	-5,55	0	0	benign	0	neutral	0,43	neutral	4,72	neutral	0,71	neutral	2,68	neutral_impact	-1,04	neutral	0,84	neutral	0,95	deleterious	0,03	2,88	0,45	0,55	neutral	0,35	neutral	0,36	neutral	0,33	neutral	0,46	1	neutral	0,56	deleterious	0,72	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	0,17	low_impact	-2,15	0,62	0,8	13,76	11,27	N	0,26	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12970	12970	C	A	MI.20611	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	634	212	P	T	Cca/Aca	-7,38	0	0	probably_damaging	1	neutral	0,44	neutral	4,66	neutral	0,32	deleterious	-7,46	medium_impact	1,94	neutral	0,7	damaging	0,14	deleterious	3,64	23,2	0,48	0,55	neutral	0,3	disease	0,61	disease	0,64	neutral	0,46	1	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,67	low_impact	-3,6	medium_impact	0,18	medium_impact	0,57	0,81	0,85	16,25	17,88	N	0,23	N	0,68	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12970	12970	C	G	MI.20612	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	634	212	P	A	Cca/Gca	-7,38	0	0	probably_damaging	1	neutral	0,58	neutral	4,73	neutral	1,5	deleterious	-7,54	low_impact	0,84	neutral	0,79	neutral	0,59	deleterious	1,84	15,24	0,41	0,5	neutral	0,29	neutral	0,44	disease	0,59	neutral	0,41	2	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	0,31	medium_impact	-0,44	0,77	0,85	16,25	17,88	N	0,3	N	0,44	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12970	12970	C	T	MI.20613	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	634	212	P	S	Cca/Tca	-7,38	0	0	probably_damaging	1	neutral	0,47	neutral	4,74	neutral	1,64	deleterious	-7,57	low_impact	1,88	neutral	0,73	damaging	0,1	deleterious	3,83	23,4	0,6	0,65	neutral	0,46	disease	0,69	disease	0,63	disease	0,62	2	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,2	medium_impact	0,51	0,43	0,8	16,25	17,88	N	0,24	N	0,5	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12971	12971	C	G	MI.20614	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	635	212	P	R	cCa/cGa	4,31	0,99	0	probably_damaging	1	neutral	0,38	neutral	4,62	neutral	-0,95	deleterious	-8,54	high_impact	3,59	neutral	0,68	damaging	0,11	deleterious	3,48	23,1	0,28	0,45	disease	0,66	disease	0,84	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,12	high_impact	2,08	0,69	0,85	16,25	17,88	N	0,48	N	0,88	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12971	12971	C	T	MI.20615	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	635	212	P	L	cCa/cTa	4,31	0,99	0	probably_damaging	1	neutral	0,69	neutral	4,87	neutral	2,62	deleterious	-9,24	neutral_impact	-0,04	neutral	0,67	damaging	0,26	deleterious	4,26	23,9	0,5	0,6	neutral	0,24	disease	0,79	disease	0,58	disease	0,53	1	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,42	low_impact	-1,24	0,77	0,85	16,25	17,88	N	0,33	N	0,93	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12971	12971	C	A	MI.20616	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	635	212	P	Q	cCa/cAa	4,31	0,99	0	probably_damaging	1	neutral	0,33	neutral	4,62	neutral	-1,1	deleterious	-7,66	high_impact	3,59	neutral	0,73	damaging	0,11	deleterious	3,95	23,6	0,3	0,45	disease	0,66	disease	0,81	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,75	low_impact	-3,6	medium_impact	0,06	high_impact	2,08	0,65	0,8	16,25	17,88	N	0,44	N	0,82	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12973	12973	C	A	MI.20617	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	637	213	L	M	Cta/Ata	-5,78	0	0	probably_damaging	1	neutral	0,34	neutral	4,52	neutral	-2,79	neutral	-1,47	low_impact	1,44	neutral	0,74	neutral	0,74	deleterious	3,61	23,2	0,4	0,5	disease	0,7	disease	0,53	neutral	0,48	disease	0,51	0	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,72	low_impact	-3,6	medium_impact	0,07	medium_impact	0,11	0,61	0,8	5,97	7,34	N	0,32	N	0,89	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12973	12973	C	G	MI.20618	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	637	213	L	V	Cta/Gta	-5,78	0	0	probably_damaging	1	neutral	0,59	neutral	4,59	neutral	-1,38	deleterious	-2,6	low_impact	1,77	neutral	0,74	damaging	0,12	deleterious	3,34	22,9	0,37	0,5	neutral	0,47	neutral	0,47	neutral	0,5	neutral	0,45	1	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,32	medium_impact	0,41	0,54	0,8	5,97	7,34	N	0,19	N	0,81	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12974	12974	T	A	MI.20619	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	638	213	L	Q	cTa/cAa	-0,73	0	0	probably_damaging	1	neutral	0,31	neutral	4,54	deleterious	-5,07	deleterious	-5,28	high_impact	3,86	neutral	0,7	damaging	0,09	deleterious	4,13	23,8	0,17	0,45	disease	0,6	disease	0,82	disease	0,58	disease	0,67	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,04	high_impact	2,32	0,52	0,8	5,97	7,34	N	0,3	N	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5992	5992	G	A	MI.2062	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	89	30	G	D	gGc/gAc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,2	deleterious	-5,21	deleterious	-3,68	high_impact	5,1	neutral	0,61	damaging	0,08	deleterious	3,67	23,3	0,09	0,55	disease	0,83	disease	0,91	disease	0,79	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,61	0,4	0,9	2,14	8,62	P	0,74	P	0,97	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12974	12974	T	G	MI.20620	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	638	213	L	R	cTa/cGa	-0,73	0	0	probably_damaging	1	neutral	0,34	neutral	4,51	deleterious	-4,9	deleterious	-5,36	high_impact	3,51	neutral	0,6	damaging	0,08	deleterious	4,06	23,7	0,13	0,4	disease	0,72	disease	0,87	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,07	high_impact	2	0,57	0,8	5,97	7,34	N	0,24	N	1	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12974	12974	T	C	MI.20621	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	638	213	L	P	cTa/cCa	-0,73	0	0	probably_damaging	1	neutral	0,36	neutral	4,5	deleterious	-5,95	deleterious	-6,26	medium_impact	2,96	neutral	0,66	damaging	0,26	deleterious	3,84	23,4	0,1	0,4	disease	0,82	disease	0,82	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,1	medium_impact	1,5	0,54	0,8	5,97	7,34	N	0,23	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12976	12976	C	A	MI.20622	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	640	214	L	M	Cta/Ata	-20	0	0	benign	0,05	neutral	0,26	neutral	4,3	deleterious	-3,48	neutral	-0,59	low_impact	1,92	neutral	0,89	neutral	0,98	neutral	1,17	11,61	0,41	0,5	neutral	0,32	neutral	0,24	neutral	0,31	neutral	0,45	1	neutral	0,72	deleterious	0,61	neutral	-6	deleterious	0,61	medium_impact	0,47	medium_impact	-0,02	medium_impact	0,55	0,68	0,85	5,47	9,57	N	0,44	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12976	12976	C	G	MI.20623	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	640	214	L	V	Cta/Gta	-20	0	0	benign	0,01	neutral	0,54	neutral	4,39	neutral	-1,84	neutral	-1,73	low_impact	1,9	neutral	0,86	neutral	0,77	deleterious	0,54	7,73	0,32	0,5	disease	0,56	neutral	0,46	neutral	0,34	disease	0,6	2	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,38	medium_impact	1,15	medium_impact	0,27	medium_impact	0,53	0,57	0,8	5,47	9,57	N	0,3	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12977	12977	T	A	MI.20624	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	641	214	L	Q	cTa/cAa	-6,47	0	0	possibly_damaging	0,81	neutral	0,33	neutral	4,27	deleterious	-5,86	deleterious	-4,13	high_impact	4,17	neutral	0,78	neutral	0,52	deleterious	4,21	23,9	0,18	0,45	disease	0,51	disease	0,81	disease	0,56	disease	0,67	3	neutral	0,84	neutral	0,26	deleterious	1	deleterious	0,7	low_impact	-1,34	medium_impact	0,06	high_impact	2,61	0,56	0,8	5,47	9,57	N	0,36	N	0,68	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12977	12977	T	G	MI.20625	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	641	214	L	R	cTa/cGa	-6,47	0	0	possibly_damaging	0,66	neutral	0,36	neutral	4,27	deleterious	-5,79	deleterious	-4,36	high_impact	4,53	neutral	0,7	neutral	0,39	deleterious	3,97	23,6	0,15	0,45	disease	0,51	disease	0,87	disease	0,68	disease	0,73	5	neutral	0,71	neutral	0,35	deleterious	1	deleterious	0,74	low_impact	-1,02	medium_impact	0,1	high_impact	2,94	0,55	0,8	5,47	9,57	N	0,45	N	0,82	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12977	12977	T	C	MI.20626	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	641	214	L	P	cTa/cCa	-6,47	0	0	possibly_damaging	0,66	neutral	0,27	neutral	4,26	deleterious	-6,01	deleterious	-5,12	high_impact	3,98	neutral	0,67	neutral	0,47	deleterious	3,72	23,3	0,18	0,45	disease	0,55	disease	0,88	disease	0,69	disease	0,74	5	neutral	0,77	neutral	0,31	deleterious	1	deleterious	0,74	low_impact	-1,02	medium_impact	-0,01	high_impact	2,43	0,61	0,8	5,47	9,57	N	0,37	N	0,9	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12979	12979	G	C	MI.20627	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	643	215	G	R	Ggc/Cgc	-2,11	0	0	probably_damaging	0,98	neutral	0,23	neutral	4,57	deleterious	-5,32	deleterious	-7,42	high_impact	3,87	neutral	0,7	damaging	0,22	deleterious	3,78	23,4	0,1	0,4	disease	0,95	disease	0,87	disease	0,73	disease	0,84	7	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,89	low_impact	-2,35	medium_impact	-0,06	high_impact	2,33	0,72	0,85	7,63	15,83	N	0,31	N	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12979	12979	G	T	MI.20628	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	643	215	G	C	Ggc/Tgc	-2,11	0	0	probably_damaging	1	neutral	0,12	neutral	4,59	deleterious	-3,45	deleterious	-8,35	low_impact	1,68	neutral	0,73	damaging	0,28	deleterious	4,03	23,7	0,19	0,45	disease	0,98	disease	0,85	disease	0,59	disease	0,8	6	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,25	medium_impact	0,33	0,58	0,8	7,63	15,83	N	0,32	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12979	12979	G	A	MI.20629	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	643	215	G	S	Ggc/Agc	-2,11	0	0	benign	0,31	neutral	0,37	neutral	4,63	deleterious	-3,56	deleterious	-5,41	medium_impact	1,97	neutral	0,76	neutral	0,55	deleterious	4,02	23,6	0,28	0,45	disease	0,88	disease	0,76	disease	0,52	disease	0,71	4	neutral	0,55	deleterious	0,53	neutral	-3	deleterious	0,82	medium_impact	-0,42	medium_impact	0,11	medium_impact	0,6	0,62	0,8	7,63	15,83	N	0,26	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5992	5992	G	C	MI.2063	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	89	30	G	A	gGc/gCc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,36	neutral	-2,5	deleterious	-3,06	medium_impact	3,42	neutral	0,79	damaging	0,14	deleterious	2,93	22	0,27	0,55	disease	0,8	disease	0,74	disease	0,59	disease	0,67	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,06	0,62	0,9	2,14	8,62	N	0,47	N	0,64	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12980	12980	G	C	MI.20630	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	644	215	G	A	gGc/gCc	5	1	0	possibly_damaging	0,84	neutral	0,48	neutral	4,66	neutral	-0,76	deleterious	-5,51	neutral_impact	0,79	neutral	0,7	neutral	0,65	deleterious	3,02	22,3	0,36	0,5	disease	0,88	disease	0,52	neutral	0,38	disease	0,64	3	neutral	0,83	neutral	0,32	neutral	-3	deleterious	0,8	low_impact	-1,43	medium_impact	0,21	medium_impact	-0,48	0,58	0,8	7,63	15,83	N	0,4	N	0,79	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12980	12980	G	T	MI.20631	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	644	215	G	V	gGc/gTc	5	1	0	probably_damaging	0,98	neutral	0,57	neutral	4,7	neutral	-2,33	deleterious	-8,38	medium_impact	2,98	neutral	0,73	neutral	0,29	deleterious	3,67	23,2	0,24	0,45	disease	0,96	disease	0,82	disease	0,63	disease	0,83	6	deleterious	0,98	neutral	0,3	deleterious	1	deleterious	0,84	low_impact	-2,35	medium_impact	0,3	medium_impact	1,52	0,46	0,8	7,63	15,83	N	0,4	N	0,98	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12980	12980	G	A	MI.20632	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	644	215	G	D	gGc/gAc	5	1	0	probably_damaging	0,96	neutral	0,13	neutral	4,56	deleterious	-6,23	deleterious	-6,47	high_impact	3,87	neutral	0,72	damaging	0,27	deleterious	3,82	23,4	0,13	0,4	disease	0,84	disease	0,89	disease	0,72	disease	0,8	6	neutral	0,98	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-2,06	medium_impact	-0,22	high_impact	2,33	0,4	0,8	7,63	15,83	N	0,5	N	0,95	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12982	12982	C	A	MI.20633	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	646	216	L	I	Ctc/Atc	-20	0	0	benign	0,08	neutral	0,45	neutral	4,43	neutral	-2,22	neutral	-1,87	neutral_impact	0,78	neutral	0,81	neutral	0,74	deleterious	2,37	18,61	0,27	0,45	neutral	0,49	neutral	0,44	neutral	0,45	neutral	0,38	2	neutral	0,49	deleterious	0,69	neutral	-6	neutral	0,42	medium_impact	0,26	medium_impact	0,18	medium_impact	-0,49	0,65	0,8	5,97	7,34	N	0,34	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12982	12982	C	T	MI.20634	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	646	216	L	F	Ctc/Ttc	-20	0	0	benign	0,11	neutral	0,76	neutral	4,24	neutral	-2,02	deleterious	-3,79	low_impact	1,54	neutral	0,75	neutral	0,67	deleterious	1,99	16,16	0,28	0,45	disease	0,75	disease	0,56	neutral	0,38	neutral	0,5	0	neutral	0,13	deleterious	0,83	neutral	-6	neutral	0,23	medium_impact	0,12	medium_impact	0,51	medium_impact	0,2	0,52	0,8	5,97	7,34	N	0,26	N	0,18	polymorphism	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12982	12982	C	G	MI.20635	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	646	216	L	V	Ctc/Gtc	-20	0	0	benign	0,39	neutral	0,59	neutral	4,24	neutral	-2,75	deleterious	-2,83	low_impact	1,6	neutral	0,76	neutral	0,45	neutral	1,72	14,5	0,28	0,45	disease	0,71	neutral	0,45	neutral	0,48	disease	0,59	2	neutral	0,36	deleterious	0,6	neutral	-6	deleterious	0,44	medium_impact	-0,56	medium_impact	0,32	medium_impact	0,26	0,64	0,8	5,97	7,34	N	0,28	N	0,53	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12983	12983	T	G	MI.20636	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	647	216	L	R	cTc/cGc	-0,27	0	0	probably_damaging	0,95	neutral	0,34	neutral	4,1	deleterious	-6,25	deleterious	-5,73	high_impact	4,51	neutral	0,62	damaging	0,27	deleterious	4,08	23,7	0,14	0,4	disease	0,94	disease	0,84	disease	0,68	disease	0,81	6	neutral	0,95	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-1,96	medium_impact	0,07	high_impact	2,92	0,38	0,8	5,97	7,34	N	0,39	N	0,95	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12983	12983	T	A	MI.20637	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	647	216	L	H	cTc/cAc	-0,27	0	0	probably_damaging	0,98	neutral	0,59	neutral	4,1	deleterious	-6,87	deleterious	-6,67	high_impact	4,51	neutral	0,68	neutral	0,3	deleterious	4,02	23,6	0,16	0,45	disease	0,96	disease	0,76	disease	0,64	disease	0,8	6	neutral	0,97	neutral	0,31	deleterious	2	deleterious	0,8	low_impact	-2,35	medium_impact	0,32	high_impact	2,92	0,38	0,8	5,97	7,34	N	0,35	N	0,85	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12983	12983	T	C	MI.20638	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	647	216	L	P	cTc/cCc	-0,27	0	0	probably_damaging	0,98	neutral	0,28	neutral	4,1	deleterious	-6,91	deleterious	-6,68	high_impact	3,96	neutral	0,64	neutral	0,29	deleterious	3,77	23,4	0,22	0,45	disease	0,96	disease	0,81	disease	0,68	disease	0,8	6	neutral	0,98	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-2,35	medium_impact	0,01	high_impact	2,41	0,44	0,8	5,97	7,34	N	0,32	N	0,9	polymorphism	0,55	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12985	12985	C	T	MI.20639	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	649	217	L	F	Ctc/Ttc	-14,72	0	0	probably_damaging	0,99	neutral	0,62	neutral	4,49	neutral	-1,28	deleterious	-3,55	low_impact	1,47	neutral	0,69	neutral	0,71	deleterious	3,92	23,5	0,25	0,45	disease	0,55	neutral	0,4	disease	0,53	disease	0,63	3	deleterious	0,99	neutral	0,32	neutral	-2	deleterious	0,69	low_impact	-2,64	medium_impact	0,35	medium_impact	0,14	0,4	0,8	15,59	14,84	N	0,31	N	0,7	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5992	5992	G	T	MI.2064	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	89	30	G	V	gGc/gTc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,22	deleterious	-4,46	deleterious	-4,71	high_impact	5,1	neutral	0,61	damaging	0,09	deleterious	3,58	23,2	0,11	0,55	disease	0,92	disease	0,89	disease	0,69	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,61	0,61	0,9	2,14	8,62	P	0,7	P	0,93	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12985	12985	C	A	MI.20640	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	649	217	L	I	Ctc/Atc	-14,72	0	0	probably_damaging	0,96	neutral	0,45	neutral	4,54	neutral	-2,24	neutral	-1,44	neutral_impact	0,04	neutral	0,78	neutral	0,93	neutral	1,32	12,35	0,26	0,45	disease	0,63	neutral	0,03	neutral	0,18	neutral	0,38	2	neutral	0,96	neutral	0,25	neutral	-2	deleterious	0,66	low_impact	-2,06	medium_impact	0,18	low_impact	-1,17	0,58	0,8	15,59	14,84	N	0,44	N	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12985	12985	C	G	MI.20641	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	649	217	L	V	Ctc/Gtc	-14,72	0	0	probably_damaging	0,94	neutral	0,55	neutral	4,52	neutral	-2,08	neutral	-2,3	low_impact	0,93	neutral	0,81	neutral	0,98	deleterious	1,91	15,66	0,26	0,45	disease	0,68	neutral	0,25	neutral	0,31	disease	0,56	1	neutral	0,94	neutral	0,31	neutral	-2	deleterious	0,7	low_impact	-1,88	medium_impact	0,28	medium_impact	-0,35	0,5	0,8	15,59	14,84	N	0,31	N	0,4	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12986	12986	T	A	MI.20642	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	650	217	L	H	cTc/cAc	-0,27	0	0	probably_damaging	1	neutral	0,4	neutral	4,35	deleterious	-6,45	deleterious	-6,33	high_impact	4,03	neutral	0,7	neutral	0,52	deleterious	4,07	23,7	0,17	0,45	disease	0,95	disease	0,62	disease	0,63	disease	0,82	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,14	high_impact	2,48	0,47	0,8	15,59	14,84	N	0,35	N	0,85	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12986	12986	T	C	MI.20643	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	650	217	L	P	cTc/cCc	-0,27	0	0	benign	0,38	neutral	0,23	neutral	4,35	deleterious	-5,73	deleterious	-6,28	high_impact	4,03	neutral	0,62	neutral	0,39	deleterious	3,84	23,4	0,19	0,45	disease	0,7	disease	0,84	disease	0,68	disease	0,76	5	neutral	0,73	neutral	0,43	neutral	-2	deleterious	0,84	medium_impact	-0,54	medium_impact	-0,06	high_impact	2,48	0,5	0,8	15,59	14,84	N	0,35	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	COSM1315746	.	.	.	.	.	.	.	.
chrM	12986	12986	T	G	MI.20644	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	650	217	L	R	cTc/cGc	-0,27	0	0	probably_damaging	0,99	neutral	0,24	neutral	4,35	deleterious	-5,93	deleterious	-5,49	high_impact	4,03	neutral	0,65	neutral	0,48	deleterious	4,12	23,8	0,15	0,4	disease	0,94	disease	0,82	disease	0,67	disease	0,79	6	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,88	low_impact	-2,64	medium_impact	-0,04	high_impact	2,48	0,46	0,8	15,59	14,84	N	0,35	N	0,97	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12988	12988	C	A	MI.20645	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	652	218	L	M	Cta/Ata	-6,7	0	0	probably_damaging	1	neutral	0,23	neutral	4,47	deleterious	-3,17	neutral	-1,84	medium_impact	2,23	neutral	0,72	damaging	0,18	deleterious	3,65	23,2	0,3	0,45	disease	0,57	neutral	0,41	neutral	0,47	disease	0,58	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,69	low_impact	-3,6	medium_impact	-0,06	medium_impact	0,83	0,65	0,8	16,25	15,32	N	0,33	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12988	12988	C	G	MI.20646	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	652	218	L	V	Cta/Gta	-6,7	0	0	probably_damaging	1	neutral	0,52	neutral	4,66	neutral	-2,34	deleterious	-2,67	low_impact	1,13	neutral	0,75	neutral	0,33	deleterious	2,24	17,8	0,3	0,45	disease	0,54	neutral	0,27	neutral	0,36	disease	0,51	0	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,25	medium_impact	-0,17	0,53	0,8	16,25	15,32	N	0,26	N	0,43	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12989	12989	T	C	MI.20647	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	653	218	L	P	cTa/cCa	-3,03	0	0	probably_damaging	1	neutral	0,24	neutral	4,36	deleterious	-6,65	deleterious	-6,58	high_impact	4,05	neutral	0,62	damaging	0,09	deleterious	3,83	23,4	0,16	0,45	disease	0,94	disease	0,82	disease	0,71	disease	0,79	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,04	high_impact	2,5	0,56	0,8	16,25	15,32	N	0,29	N	0,91	polymorphism	0,88	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12989	12989	T	A	MI.20648	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	653	218	L	Q	cTa/cAa	-3,03	0	0	probably_damaging	1	neutral	0,3	neutral	4,36	deleterious	-6,27	deleterious	-5,66	high_impact	4,39	neutral	0,68	damaging	0,1	deleterious	3,99	23,6	0,16	0,45	disease	0,92	disease	0,74	disease	0,59	disease	0,77	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,03	high_impact	2,81	0,55	0,8	16,25	15,32	N	0,36	N	0,95	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12989	12989	T	G	MI.20649	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	653	218	L	R	cTa/cGa	-3,03	0	0	probably_damaging	1	neutral	0,35	neutral	4,37	deleterious	-6,04	deleterious	-5,67	high_impact	4,39	damaging	0,6	damaging	0,08	deleterious	4,09	23,7	0,14	0,4	disease	0,91	disease	0,82	disease	0,71	disease	0,79	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,08	high_impact	2,81	0,53	0,8	16,25	15,32	N	0,35	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5994	5994	A	T	MI.2065	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	91	31	T	S	Aca/Tca	-12,83	0	0	benign	0	neutral	0,14	neutral	2,79	neutral	-2,9	neutral	-1,56	low_impact	1	neutral	0,7	neutral	0,61	deleterious	0,16	4,3	0,42	0,55	neutral	0,4	disease	0,57	neutral	0,28	neutral	0,46	1	neutral	0,86	deleterious	0,57	neutral	-6	neutral	0,18	high_impact	2,07	medium_impact	-0,25	medium_impact	-0,18	0,73	0,9	8,97	51,24	N	0,48	N	0,79	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12991	12991	G	A	MI.20650	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	655	219	A	T	Gca/Aca	-3,03	0	0	probably_damaging	1	neutral	0,53	neutral	4,24	deleterious	-3,04	deleterious	-3,83	high_impact	3,6	damaging	0,52	damaging	0,02	deleterious	4,15	23,8	0,26	0,45	disease	0,86	disease	0,71	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,26	high_impact	2,09	0,64	0,8	28,03	7,19	N	0,23	N	0,94	polymorphism	0,97	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12991	12991	G	C	MI.20651	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	655	219	A	P	Gca/Cca	-3,03	0	0	probably_damaging	1	neutral	0,22	neutral	4,18	deleterious	-5,46	deleterious	-4,79	high_impact	4,69	damaging	0,54	damaging	0,02	deleterious	3,75	23,3	0,16	0,45	disease	0,97	disease	0,87	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,07	high_impact	3,08	0,42	0,8	28,03	7,19	N	0,53	P	0,96	polymorphism	0,9	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12991	12991	G	T	MI.20652	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	655	219	A	S	Gca/Tca	-3,03	0	0	probably_damaging	1	neutral	0,6	neutral	4,33	neutral	-2,95	deleterious	-2,87	medium_impact	3,06	damaging	0,55	damaging	0,04	deleterious	3,62	23,2	0,3	0,45	disease	0,76	disease	0,76	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,33	medium_impact	1,59	0,43	0,8	28,03	7,19	N	0,18	N	0,98	polymorphism	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12992	12992	C	T	MI.20653	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	656	219	A	V	gCa/gTa	7,07	1	0	probably_damaging	1	neutral	0,6	neutral	4,21	neutral	-1,48	deleterious	-3,83	high_impact	3,65	damaging	0,52	damaging	0,02	deleterious	4,35	24,1	0,33	0,5	disease	0,83	disease	0,76	disease	0,62	disease	0,68	4	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,33	high_impact	2,13	0,64	0,8	28,03	7,19	N	0,51	P	0,76	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12992	12992	C	A	MI.20654	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	656	219	A	E	gCa/gAa	7,07	1	0	probably_damaging	1	neutral	0,33	neutral	4,19	deleterious	-5,42	deleterious	-4,79	high_impact	4,69	damaging	0,57	damaging	0,02	deleterious	4,43	24,2	0,12	0,4	disease	0,97	disease	0,85	disease	0,72	disease	0,79	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,06	high_impact	3,08	0,42	0,8	28,03	7,19	P	0,64	P	0,99	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12992	12992	C	G	MI.20655	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	656	219	A	G	gCa/gGa	7,07	1	0	probably_damaging	1	neutral	0,44	neutral	4,53	neutral	0,69	deleterious	-3,83	low_impact	1,03	damaging	0,54	damaging	0,06	deleterious	3,85	23,4	0,3	0,45	neutral	0,36	neutral	0,45	disease	0,51	neutral	0,42	2	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,18	medium_impact	-0,26	0,49	0,8	28,03	7,19	N	0,46	N	0,82	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12994	12994	G	A	MI.20656	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	658	220	A	T	Gca/Aca	-6,7	0	0	probably_damaging	1	neutral	0,42	neutral	4,47	deleterious	-3,36	deleterious	-3,69	high_impact	3,73	damaging	0,5	damaging	0,09	deleterious	4,14	23,8	0,34	0,5	disease	0,72	disease	0,73	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,16	high_impact	2,2	0,55	0,8	7,13	10,05	N	0,29	N	0,94	polymorphism	0,99	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12994	12994	G	T	MI.20657	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	658	220	A	S	Gca/Tca	-6,7	0	0	probably_damaging	1	neutral	0,52	neutral	4,49	deleterious	-3,55	deleterious	-2,66	medium_impact	3,04	damaging	0,49	neutral	0,66	deleterious	3,61	23,2	0,3	0,45	disease	0,81	disease	0,75	disease	0,52	disease	0,61	2	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,25	medium_impact	1,57	0,42	0,8	7,13	10,05	N	0,34	N	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12994	12994	G	C	MI.20658	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	658	220	A	P	Gca/Cca	-6,7	0	0	probably_damaging	1	neutral	0,2	neutral	4,43	deleterious	-4,08	deleterious	-4,68	medium_impact	3,31	damaging	0,53	damaging	0,08	deleterious	3,81	23,4	0,17	0,45	disease	0,55	disease	0,86	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	-0,1	medium_impact	1,82	0,51	0,8	7,13	10,05	N	0,3	N	0,96	polymorphism	0,98	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12995	12995	C	G	MI.20659	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	659	220	A	G	gCa/gGa	5	1	0	probably_damaging	1	neutral	0,42	neutral	4,44	neutral	-1,54	deleterious	-3,72	medium_impact	3,12	damaging	0,48	damaging	0,13	deleterious	3,84	23,4	0,29	0,45	disease	0,83	disease	0,69	disease	0,61	disease	0,68	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,16	medium_impact	1,65	0,59	0,8	7,13	10,05	N	0,5	N	0,82	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5994	5994	A	G	MI.2066	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	91	31	T	A	Aca/Gca	-12,83	0	0	benign	0,05	neutral	0,08	neutral	2,76	neutral	-2,12	neutral	-1,99	medium_impact	2	damaging	0,59	neutral	0,72	neutral	1,31	12,33	0,52	0,6	neutral	0,3	disease	0,62	neutral	0,3	neutral	0,46	1	neutral	0,91	deleterious	0,52	neutral	-3	neutral	0,18	medium_impact	0,45	medium_impact	-0,4	medium_impact	0,75	0,54	0,9	8,97	51,24	N	0,52	P	0,69	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12995	12995	C	T	MI.20660	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	659	220	A	V	gCa/gTa	5	1	0	probably_damaging	1	neutral	0,53	neutral	4,55	neutral	-1,89	deleterious	-3,79	medium_impact	2,87	damaging	0,45	damaging	0,07	deleterious	4,33	24	0,49	0,55	disease	0,64	disease	0,75	disease	0,61	disease	0,59	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,26	medium_impact	1,42	0,58	0,8	7,13	10,05	P	0,55	P	0,76	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12995	12995	C	A	MI.20661	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	659	220	A	E	gCa/gAa	5	1	0	probably_damaging	1	neutral	0,28	neutral	4,43	deleterious	-5,74	deleterious	-4,65	high_impact	5	damaging	0,56	damaging	0,08	deleterious	4,42	24,2	0,14	0,4	disease	0,93	disease	0,84	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,01	high_impact	3,36	0,42	0,8	7,13	10,05	P	0,71	P	0,99	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12997	12997	G	A	MI.20662	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	661	221	A	T	Gca/Aca	-3,03	0	0	benign	0,02	neutral	0,45	neutral	4,52	neutral	-2,66	neutral	2,25	neutral_impact	0,14	neutral	0,84	neutral	0,95	neutral	1,24	11,94	0,56	0,6	disease	0,51	neutral	0,06	neutral	0,22	neutral	0,22	6	neutral	0,53	deleterious	0,72	neutral	-6	deleterious	0,57	medium_impact	0,86	medium_impact	0,18	low_impact	-1,08	0,65	0,8	10,78	11,53	N	0,43	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12997	12997	G	C	MI.20663	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	661	221	A	P	Gca/Cca	-3,03	0	0	possibly_damaging	0,81	neutral	0,22	neutral	4,47	deleterious	-5,78	neutral	-1,95	medium_impact	3,48	neutral	0,63	neutral	0,36	deleterious	3,75	23,3	0,18	0,45	disease	0,93	disease	0,86	disease	0,7	disease	0,77	5	neutral	0,88	neutral	0,21	NA	0	deleterious	0,85	low_impact	-1,34	medium_impact	-0,07	medium_impact	1,98	0,56	0,8	10,78	11,53	N	0,32	N	0,74	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12997	12997	G	T	MI.20664	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	661	221	A	S	Gca/Tca	-3,03	0	0	benign	0,36	neutral	0,48	neutral	4,51	deleterious	-3,2	neutral	-0,1	medium_impact	2,59	neutral	0,85	neutral	0,69	deleterious	3,31	22,9	0,46	0,55	disease	0,76	neutral	0,48	neutral	0,47	disease	0,6	2	neutral	0,44	deleterious	0,56	neutral	-3	deleterious	0,63	medium_impact	-0,51	medium_impact	0,21	medium_impact	1,16	0,49	0,8	10,78	11,53	N	0,35	N	0,61	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12998	12998	C	G	MI.20665	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	662	221	A	G	gCa/gGa	0,41	0	0	possibly_damaging	0,56	neutral	0,41	neutral	4,54	neutral	-2,22	neutral	-2,41	medium_impact	3,48	neutral	0,79	neutral	0,58	deleterious	3,57	23,2	0,33	0,5	disease	0,51	disease	0,51	disease	0,55	disease	0,65	3	neutral	0,61	neutral	0,43	NA	0	deleterious	0,56	medium_impact	-0,85	medium_impact	0,15	medium_impact	1,98	0,45	0,8	10,78	11,53	N	0,32	N	0,49	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12998	12998	C	A	MI.20666	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	662	221	A	E	gCa/gAa	0,41	0	0	possibly_damaging	0,48	neutral	0,33	neutral	4,47	deleterious	-5,57	neutral	-1,95	medium_impact	3,13	neutral	0,74	neutral	0,52	deleterious	4,12	23,8	0,15	0,4	disease	0,91	disease	0,78	disease	0,69	disease	0,79	6	neutral	0,64	neutral	0,43	NA	0	deleterious	0,7	medium_impact	-0,71	medium_impact	0,06	medium_impact	1,66	0,51	0,8	10,78	11,53	N	0,34	N	0,74	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	12998	12998	C	T	MI.20667	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	662	221	A	V	gCa/gTa	0,41	0	0	benign	0,03	neutral	0,55	neutral	4,6	neutral	-1,28	neutral	-0,86	neutral_impact	0,3	neutral	0,78	neutral	0,78	deleterious	4,14	23,8	0,51	0,6	disease	0,5	neutral	0,49	neutral	0,49	neutral	0,36	3	neutral	0,42	deleterious	0,76	neutral	-6	deleterious	0,62	medium_impact	0,69	medium_impact	0,28	medium_impact	-0,93	0,64	0,8	10,78	11,53	N	0,27	N	0,47	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13000	13000	G	A	MI.20668	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	664	222	G	S	Ggc/Agc	-8,3	0	0	probably_damaging	1	neutral	0,61	neutral	4,59	deleterious	-3,64	deleterious	-5,74	low_impact	1,79	damaging	0,36	damaging	0,04	deleterious	4,11	23,7	0,45	0,55	disease	0,78	disease	0,78	disease	0,6	disease	0,53	1	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,8	low_impact	-3,6	medium_impact	0,34	medium_impact	0,43	0,75	0,85	24,38	7,11	N	0,39	N	1	polymorphism	0,9	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13000	13000	G	T	MI.20669	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	664	222	G	C	Ggc/Tgc	-8,3	0	0	probably_damaging	1	neutral	0,17	neutral	4,57	deleterious	-6,25	deleterious	-8,62	high_impact	4,33	damaging	0,46	damaging	0,01	deleterious	4,08	23,7	0,13	0,4	disease	0,93	disease	0,88	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,15	high_impact	2,75	0,68	0,85	24,38	7,11	N	0,35	N	0,97	polymorphism	0,69	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5994	5994	A	C	MI.2067	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	91	31	T	P	Aca/Cca	-12,83	0	0	possibly_damaging	0,57	deleterious	0	neutral	2,7	deleterious	-4,38	deleterious	-2,74	high_impact	4	neutral	0,63	neutral	0,46	deleterious	2,93	22	0,13	0,55	disease	0,68	disease	0,9	disease	0,67	disease	0,76	5	deleterious	1	neutral	0,22	deleterious	5	deleterious	0,6	medium_impact	-0,87	low_impact	-1,48	high_impact	2,59	0,66	0,9	8,97	51,24	N	0,36	N	0,92	polymorphism	0,95	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13000	13000	G	C	MI.20670	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	664	222	G	R	Ggc/Cgc	-8,3	0	0	probably_damaging	1	neutral	0,38	neutral	4,57	deleterious	-6,06	deleterious	-7,66	high_impact	4,67	damaging	0,5	damaging	0,02	deleterious	3,89	23,5	0,09	0,35	disease	0,91	disease	0,89	disease	0,78	disease	0,76	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,12	high_impact	3,06	0,62	0,8	24,38	7,11	N	0,49	N	1	polymorphism	0,82	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13001	13001	G	T	MI.20671	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	665	222	G	V	gGc/gTc	5,92	1	0	probably_damaging	1	neutral	0,61	neutral	4,82	neutral	-1,91	deleterious	-8,62	high_impact	4,12	damaging	0,44	damaging	0,02	deleterious	3,7	23,3	0,18	0,45	neutral	0,47	disease	0,86	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,34	high_impact	2,56	0,63	0,8	24,38	7,11	N	0,53	P	0,98	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13001	13001	G	A	MI.20672	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	665	222	G	D	gGc/gAc	5,92	1	0	probably_damaging	1	neutral	0,27	neutral	4,56	deleterious	-7,05	deleterious	-6,7	high_impact	4,67	damaging	0,46	damaging	0,02	deleterious	3,78	23,4	0,09	0,4	disease	0,96	disease	0,9	disease	0,77	disease	0,77	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,01	high_impact	3,06	0,49	0,8	24,38	7,11	P	0,62	P	0,95	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13001	13001	G	C	MI.20673	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	665	222	G	A	gGc/gCc	5,92	1	0	probably_damaging	1	neutral	0,71	neutral	4,66	neutral	-2,48	deleterious	-5,74	low_impact	1,72	damaging	0,46	damaging	0,06	deleterious	3,04	22,4	0,47	0,55	disease	0,6	disease	0,67	disease	0,54	disease	0,53	1	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	0,45	medium_impact	0,37	0,57	0,8	24,38	7,11	N	0,41	N	0,79	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13003	13003	A	G	MI.20674	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	667	223	K	E	Aaa/Gaa	-5,32	0	0	probably_damaging	1	neutral	0,3	neutral	3,17	deleterious	-5,8	deleterious	-3,83	high_impact	5,24	damaging	0,36	neutral	0,37	deleterious	3,93	23,5	0,23	0,45	disease	0,85	disease	0,77	disease	0,8	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,03	high_impact	3,58	0,51	0,8	27,69	7,26	P	0,78	P	0,84	polymorphism	0,97	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13003	13003	A	C	MI.20675	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	667	223	K	Q	Aaa/Caa	-5,32	0	0	probably_damaging	1	neutral	0,32	neutral	3,17	deleterious	-5,99	deleterious	-3,83	high_impact	5,24	damaging	0,4	neutral	0,41	deleterious	3,4	23	0,25	0,45	disease	0,87	disease	0,76	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,05	high_impact	3,58	0,5	0,8	27,69	7,26	P	0,76	P	0,82	polymorphism	0,98	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13004	13004	A	T	MI.20676	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	668	223	K	M	aAa/aTa	8,44	1	0	probably_damaging	1	neutral	0,23	neutral	3,13	deleterious	-8,44	deleterious	-5,74	high_impact	4,89	damaging	0,4	neutral	0,47	deleterious	3,89	23,5	0,17	0,45	disease	0,93	disease	0,78	disease	0,79	disease	0,76	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,06	high_impact	3,26	0,4	0,8	27,69	7,26	P	0,81	P	0,4	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13004	13004	A	C	MI.20677	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	668	223	K	T	aAa/aCa	8,44	1	0	probably_damaging	1	neutral	0,42	neutral	3,15	deleterious	-6,65	deleterious	-5,74	high_impact	5,24	damaging	0,37	neutral	0,35	deleterious	3,57	23,1	0,17	0,45	disease	0,72	disease	0,72	disease	0,76	disease	0,72	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,16	high_impact	3,58	0,36	0,8	27,69	7,26	P	0,8	P	0,75	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13005	13005	A	C	MI.20678	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	669	223	K	N	aaA/aaC	8,44	1	0	probably_damaging	1	neutral	0,32	neutral	3,18	deleterious	-5,54	deleterious	-4,79	high_impact	4,89	damaging	0,29	neutral	0,35	deleterious	3,74	23,3	0,29	0,45	disease	0,91	disease	0,77	disease	0,78	disease	0,75	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,05	high_impact	3,26	0,38	0,8	27,69	7,26	P	0,93	P	0,63	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13005	13005	A	T	MI.20679	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	669	223	K	N	aaA/aaT	8,44	1	0	probably_damaging	1	neutral	0,32	neutral	3,18	deleterious	-5,54	deleterious	-4,79	high_impact	4,89	damaging	0,29	neutral	0,35	deleterious	3,84	23,4	0,29	0,45	disease	0,91	disease	0,77	disease	0,78	disease	0,75	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,05	high_impact	3,26	0,38	0,8	27,69	7,26	P	0,93	P	0,63	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5995	5995	C	A	MI.2068	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	92	31	T	K	aCa/aAa	5,68	1	0	benign	0,2	deleterious	0	neutral	2,71	deleterious	-3,43	deleterious	-2,64	high_impact	4,34	neutral	0,67	neutral	0,44	deleterious	2,47	19,26	0,17	0,55	disease	0,52	disease	0,9	disease	0,59	disease	0,75	5	deleterious	1	neutral	0,4	deleterious	2	neutral	0,42	medium_impact	-0,19	low_impact	-1,48	high_impact	2,91	0,75	0,9	8,97	51,24	P	0,49	N	0,88	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13006	13006	T	G	MI.20680	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	670	224	S	A	Tca/Gca	2,48	1	0	probably_damaging	1	neutral	0,62	neutral	4,5	neutral	-1,2	deleterious	-2,87	high_impact	4,18	damaging	0,38	damaging	0,08	deleterious	3,67	23,3	0,47	0,55	disease	0,62	disease	0,57	disease	0,66	disease	0,65	3	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,35	high_impact	2,62	0,68	0,85	29,19	7,24	P	0,63	P	0,49	disease_causing	0,95	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13006	13006	T	A	MI.20681	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	670	224	S	T	Tca/Aca	2,48	1	0	probably_damaging	1	neutral	0,48	neutral	4,45	deleterious	-3,18	deleterious	-2,87	high_impact	4,87	damaging	0,38	damaging	0,03	deleterious	3,87	23,5	0,36	0,5	disease	0,79	disease	0,62	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,21	high_impact	3,25	0,68	0,85	29,19	7,24	P	0,7	P	0,71	disease_causing	0,98	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13006	13006	T	C	MI.20682	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	670	224	S	P	Tca/Cca	2,48	1	0	probably_damaging	1	neutral	0,23	neutral	4,4	deleterious	-6,04	deleterious	-4,79	high_impact	5,22	damaging	0,35	damaging	0,04	deleterious	3,97	23,6	0,33	0,5	disease	0,95	disease	0,82	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,06	high_impact	3,57	0,6	0,8	29,19	7,24	P	0,66	P	0,98	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13007	13007	C	G	MI.20683	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	671	224	S	W	tCa/tGa	5,69	1	0	probably_damaging	1	neutral	0,2	neutral	4,39	deleterious	-7,04	deleterious	-6,7	high_impact	5,22	damaging	0,43	damaging	0,02	deleterious	4,27	24	0,2	0,45	disease	0,97	disease	0,87	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,1	high_impact	3,57	0,37	0,8	29,19	7,24	P	0,64	P	0,99	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13007	13007	C	T	MI.20684	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	671	224	S	L	tCa/tTa	5,69	1	0	probably_damaging	1	neutral	0,72	neutral	4,67	neutral	-2,04	deleterious	-5,74	high_impact	5,22	damaging	0,37	damaging	0,01	deleterious	4,53	24,3	0,31	0,45	neutral	0,49	disease	0,84	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,46	high_impact	3,57	0,8	0,85	29,19	7,24	P	0,72	P	0,99	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13009	13009	G	A	MI.20685	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	673	225	A	T	Gcc/Acc	-10,6	0	0	probably_damaging	1	neutral	0,52	neutral	4,35	neutral	-2,02	deleterious	-3,83	high_impact	4,26	damaging	0,27	damaging	0,11	deleterious	4,17	23,8	0,36	0,5	disease	0,83	disease	0,69	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,25	high_impact	2,69	0,76	0,85	27,03	7,24	P	0,69	P	0,94	polymorphism	0,97	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13009	13009	G	C	MI.20686	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	673	225	A	P	Gcc/Ccc	-10,6	0	0	probably_damaging	1	neutral	0,2	neutral	4,56	neutral	-0,37	deleterious	-4,79	high_impact	4,81	damaging	0,32	damaging	0,1	deleterious	3,81	23,4	0,26	0,45	disease	0,67	disease	0,8	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	-0,1	high_impact	3,19	0,82	0,85	27,03	7,24	P	0,63	P	0,96	polymorphism	0,89	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13009	13009	G	T	MI.20687	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	673	225	A	S	Gcc/Tcc	-10,6	0	0	probably_damaging	1	neutral	0,65	neutral	4,43	neutral	-1,22	deleterious	-2,87	medium_impact	2,88	damaging	0,35	damaging	0,11	deleterious	3,64	23,2	0,32	0,5	disease	0,74	disease	0,68	disease	0,62	disease	0,57	1	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,38	medium_impact	1,43	0,75	0,85	27,03	7,24	N	0,45	N	0,98	polymorphism	0,99	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13010	13010	C	T	MI.20688	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	674	225	A	V	gCc/gTc	5,92	1	0	probably_damaging	1	neutral	0,63	neutral	4,26	deleterious	-4,3	deleterious	-3,83	high_impact	4,61	damaging	0,2	damaging	0,06	deleterious	4,38	24,1	0,42	0,55	disease	0,81	disease	0,71	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,36	high_impact	3,01	0,86	0,9	27,03	7,24	P	0,85	P	0,76	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13010	13010	C	A	MI.20689	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	674	225	A	D	gCc/gAc	5,92	1	0	probably_damaging	1	neutral	0,22	neutral	4,26	deleterious	-4,88	deleterious	-5,74	high_impact	5,16	damaging	0,4	damaging	0,1	deleterious	4,56	24,4	0,19	0,45	disease	0,94	disease	0,86	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,07	high_impact	3,51	0,65	0,8	27,03	7,24	P	0,78	P	0,95	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5995	5995	C	T	MI.2069	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	92	31	T	M	aCa/aTa	5,68	1	0	benign	0,07	deleterious	0,01	neutral	2,76	neutral	-2,53	neutral	-2,4	medium_impact	2,02	damaging	0,51	neutral	0,65	deleterious	0,84	9,73	0,27	0,55	neutral	0,24	disease	0,74	neutral	0,32	disease	0,53	1	deleterious	0,99	deleterious	0,47	deleterious	1	neutral	0,18	medium_impact	0,3	medium_impact	-0,92	medium_impact	0,77	0,79	0,9	8,97	51,24	P	0,57	P	0,96	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13010	13010	C	G	MI.20690	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	674	225	A	G	gCc/gGc	5,92	1	0	probably_damaging	1	neutral	0,44	neutral	4,59	neutral	-0,25	deleterious	-3,83	high_impact	3,55	damaging	0,29	damaging	0,12	deleterious	3,91	23,5	0,37	0,5	disease	0,63	disease	0,6	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,75	low_impact	-3,6	medium_impact	0,18	high_impact	2,04	0,81	0,85	27,03	7,24	P	0,88	P	0,82	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13012	13012	C	A	MI.20691	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	676	226	Q	K	Caa/Aaa	-7,16	0	0	probably_damaging	1	neutral	0,68	neutral	4,43	neutral	-2,19	deleterious	-3,83	high_impact	5,21	damaging	0,39	damaging	0,27	deleterious	3,92	23,5	0,39	0,5	disease	0,9	disease	0,7	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,41	high_impact	3,56	0,57	0,8	27,69	7,2	P	0,73	P	0,96	disease_causing	0,55	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13012	13012	C	G	MI.20692	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	676	226	Q	E	Caa/Gaa	-7,16	0	0	probably_damaging	1	neutral	0,69	neutral	4,42	deleterious	-4,93	deleterious	-2,87	high_impact	5,21	damaging	0,39	neutral	0,33	deleterious	3,01	22,3	0,38	0,5	disease	0,91	disease	0,54	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,42	high_impact	3,56	0,52	0,8	27,69	7,2	P	0,69	P	0,92	polymorphism	0,63	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13013	13013	A	T	MI.20693	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	677	226	Q	L	cAa/cTa	7,07	1	0	probably_damaging	1	neutral	0,75	neutral	4,62	neutral	-0,98	deleterious	-6,7	high_impact	3,71	damaging	0,32	neutral	0,33	deleterious	3,75	23,3	0,27	0,45	disease	0,54	disease	0,75	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,5	high_impact	2,19	0,37	0,8	27,69	7,2	P	0,77	P	0,96	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13013	13013	A	C	MI.20694	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	677	226	Q	P	cAa/cCa	7,07	1	0	probably_damaging	1	neutral	0,34	neutral	4,41	deleterious	-5,6	deleterious	-5,74	high_impact	5,21	damaging	0,37	damaging	0,26	deleterious	3,24	22,8	0,29	0,45	disease	0,94	disease	0,75	disease	0,68	disease	0,77	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,07	high_impact	3,56	0,55	0,8	27,69	7,2	P	0,76	P	0,95	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13013	13013	A	G	MI.20695	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	677	226	Q	R	cAa/cGa	7,07	1	0	probably_damaging	1	neutral	0,51	neutral	4,42	deleterious	-5,17	deleterious	-3,83	high_impact	4,86	damaging	0,41	damaging	0,28	deleterious	3,38	22,9	0,41	0,5	disease	0,92	disease	0,7	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,24	high_impact	3,24	0,48	0,8	27,69	7,2	P	0,85	P	0,85	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13014	13014	A	C	MI.20696	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	678	226	Q	H	caA/caC	8,44	1	0	probably_damaging	1	neutral	0,5	neutral	4,41	deleterious	-5,83	deleterious	-4,79	high_impact	4,86	damaging	0,37	damaging	0,24	deleterious	3,39	23	0,52	0,6	disease	0,94	disease	0,63	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,23	high_impact	3,24	0,72	0,85	27,69	7,2	P	0,83	P	0,94	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13014	13014	A	T	MI.20697	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	678	226	Q	H	caA/caT	8,44	1	0	probably_damaging	1	neutral	0,5	neutral	4,41	deleterious	-5,83	deleterious	-4,79	high_impact	4,86	damaging	0,37	damaging	0,24	deleterious	3,69	23,3	0,52	0,6	disease	0,94	disease	0,63	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,23	high_impact	3,24	0,72	0,85	27,69	7,2	P	0,85	P	0,94	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13015	13015	T	G	MI.20698	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	679	227	L	V	Tta/Gta	3,85	1	0	possibly_damaging	0,81	neutral	0,51	neutral	4,64	neutral	0,72	neutral	-1	low_impact	0,96	damaging	0,57	neutral	0,74	deleterious	3,34	22,9	0,62	0,65	neutral	0,5	neutral	0,43	disease	0,54	neutral	0,42	2	neutral	0,79	neutral	0,35	neutral	-3	deleterious	0,72	low_impact	-1,34	medium_impact	0,24	medium_impact	-0,33	0,75	0,85	12,27	16,68	P	0,53	P	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13015	13015	T	A	MI.20699	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	679	227	L	M	Tta/Ata	3,85	1	0	probably_damaging	0,98	neutral	0,22	neutral	4,51	neutral	-1,56	neutral	-0,07	low_impact	1,29	neutral	0,61	neutral	0,6	deleterious	3,66	23,2	0,4	0,5	disease	0,76	neutral	0,48	neutral	0,5	disease	0,59	2	deleterious	0,98	neutral	0,12	neutral	-2	deleterious	0,78	low_impact	-2,35	medium_impact	-0,07	medium_impact	-0,02	0,75	0,85	12,27	16,68	P	0,55	P	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8623	8623	A	G	MI.207	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	97	33	T	A	Acc/Gcc	-15,14	0	0	benign	0	neutral	0,41	neutral	4,35	neutral	-0,24	neutral	-2,41	low_impact	1,8	neutral	0,97	neutral	0,95	deleterious	0,69	8,74	0,62	0,7	neutral	0,41	neutral	0,3	disease	0,57	neutral	0,48	0	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,15	high_impact	2,09	medium_impact	0,2	medium_impact	0,45	0,26	0,9	19,47	19,69	N	0,37	N	0,33	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5997	5997	G	C	MI.2070	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	94	32	A	P	Gct/Cct	-12,13	0	0	probably_damaging	1	deleterious	0,01	neutral	2,72	neutral	-2,82	neutral	-1,77	medium_impact	3,42	neutral	0,61	neutral	0,39	deleterious	3,67	23,2	0,09	0,55	disease	0,69	disease	0,88	disease	0,67	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,87	low_impact	-3,58	medium_impact	-0,92	high_impact	2,06	0,82	0,9	8,38	34,31	N	0,31	N	0,85	polymorphism	0,99	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13016	13016	T	C	MI.20700	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	680	227	L	S	tTa/tCa	3,63	1	0	probably_damaging	0,97	neutral	0,41	neutral	4,53	neutral	-2,8	neutral	-1,99	medium_impact	3,13	damaging	0,59	neutral	0,63	deleterious	3,76	23,3	0,38	0,5	disease	0,86	disease	0,58	disease	0,53	disease	0,61	2	neutral	0,97	neutral	0,22	deleterious	1	deleterious	0,83	low_impact	-2,18	medium_impact	0,15	medium_impact	1,66	0,72	0,85	12,27	16,68	N	0,47	N	0,71	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13016	13016	T	G	MI.20701	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	680	227	L	W	tTa/tGa	3,63	1	0	probably_damaging	0,99	neutral	0,19	neutral	4,55	neutral	-1,63	neutral	0,7	medium_impact	2,44	damaging	0,58	neutral	0,49	deleterious	3,75	23,3	0,21	0,45	disease	0,75	disease	0,69	disease	0,56	disease	0,69	4	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,81	low_impact	-2,64	medium_impact	-0,12	medium_impact	1,03	0,61	0,8	12,27	16,68	P	0,52	P	0,49	polymorphism	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13017	13017	A	C	MI.20702	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	681	227	L	F	ttA/ttC	7,3	1	0	benign	0,12	neutral	0,72	neutral	4,69	neutral	1,29	neutral	5,25	neutral_impact	-1,62	neutral	0,77	neutral	0,92	deleterious	0,69	8,74	0,47	0,55	neutral	0,37	neutral	0,05	neutral	0,15	neutral	0,23	5	neutral	0,17	deleterious	0,8	neutral	-6	deleterious	0,67	medium_impact	0,08	medium_impact	0,46	low_impact	-2,68	0,64	0,8	12,27	16,68	P	0,56	P	0,02	polymorphism	0,96	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13017	13017	A	T	MI.20703	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	681	227	L	F	ttA/ttT	7,3	1	0	benign	0,12	neutral	0,72	neutral	4,69	neutral	1,29	neutral	5,25	neutral_impact	-1,62	neutral	0,77	neutral	0,92	deleterious	0,77	9,26	0,47	0,55	neutral	0,37	neutral	0,05	neutral	0,15	neutral	0,23	5	neutral	0,17	deleterious	0,8	neutral	-6	deleterious	0,67	medium_impact	0,08	medium_impact	0,46	low_impact	-2,68	0,64	0,8	12,27	16,68	P	0,56	P	0,02	polymorphism	0,96	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13018	13018	G	C	MI.20704	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	682	228	G	R	Ggt/Cgt	-4,4	0	0	probably_damaging	1	neutral	0,35	neutral	4,55	deleterious	-4,63	deleterious	-7,42	high_impact	3,96	neutral	0,67	damaging	0,05	deleterious	3,89	23,5	0,21	0,45	disease	0,86	disease	0,83	disease	0,8	disease	0,74	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,08	high_impact	2,41	0,75	0,85	10,78	6,92	N	0,36	N	1	polymorphism	0,8	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13018	13018	G	T	MI.20705	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	682	228	G	C	Ggt/Tgt	-4,4	0	0	probably_damaging	1	neutral	0,18	neutral	4,54	deleterious	-5,32	deleterious	-8,35	high_impact	3,96	neutral	0,63	damaging	0,05	deleterious	4,13	23,8	0,22	0,45	disease	0,91	disease	0,84	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,13	high_impact	2,41	0,55	0,8	10,78	6,92	N	0,32	N	0,97	polymorphism	0,67	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13018	13018	G	A	MI.20706	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	682	228	G	S	Ggt/Agt	-4,4	0	0	probably_damaging	1	neutral	0,42	neutral	4,58	neutral	-2,89	deleterious	-5,55	medium_impact	3,27	damaging	0,48	neutral	0,4	deleterious	4,08	23,7	0,27	0,45	disease	0,79	disease	0,71	disease	0,62	disease	0,52	0	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,16	medium_impact	1,78	0,66	0,8	10,78	6,92	N	0,34	N	1	polymorphism	0,89	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13019	13019	G	A	MI.20707	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	683	228	G	D	gGt/gAt	2,94	1	0	probably_damaging	1	neutral	0,21	neutral	4,55	deleterious	-5,08	deleterious	-6,49	high_impact	3,96	neutral	0,7	damaging	0,06	deleterious	3,76	23,3	0,21	0,45	disease	0,91	disease	0,86	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,09	high_impact	2,41	0,43	0,8	10,78	6,92	P	0,49	N	0,95	polymorphism	0,58	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13019	13019	G	T	MI.20708	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	683	228	G	V	gGt/gTt	2,94	1	0	probably_damaging	1	neutral	0,51	neutral	4,59	deleterious	-3,27	deleterious	-8,35	medium_impact	3,27	damaging	0,57	damaging	0,05	deleterious	3,68	23,3	0,24	0,45	disease	0,67	disease	0,81	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,24	medium_impact	1,78	0,54	0,8	10,78	6,92	N	0,34	N	0,98	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13019	13019	G	C	MI.20709	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	683	228	G	A	gGt/gCt	2,94	1	0	probably_damaging	1	neutral	0,52	neutral	4,62	neutral	-2,41	deleterious	-5,56	high_impact	3,62	neutral	0,6	damaging	0,09	deleterious	3,05	22,4	0,26	0,45	disease	0,51	disease	0,59	disease	0,66	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,25	high_impact	2,1	0,63	0,8	10,78	6,92	N	0,36	N	0,79	polymorphism	0,84	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5997	5997	G	A	MI.2071	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	94	32	A	T	Gct/Act	-12,13	0	0	probably_damaging	1	deleterious	0,01	neutral	2,79	neutral	-0,32	neutral	-0,91	medium_impact	2,25	neutral	0,63	neutral	0,61	deleterious	3,99	23,6	0,39	0,55	neutral	0,42	neutral	0,45	neutral	0,31	neutral	0,49	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,71	low_impact	-3,58	medium_impact	-0,92	medium_impact	0,98	0,81	0,9	8,38	34,31	N	0,49	N	0,2	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13021	13021	C	A	MI.20710	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	685	229	L	I	Ctc/Atc	-10,83	0	0	probably_damaging	1	neutral	0,43	neutral	4,19	deleterious	-4,09	neutral	-1,86	high_impact	4,05	damaging	0,43	damaging	0,05	deleterious	4,03	23,7	0,37	0,5	disease	0,65	disease	0,56	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,17	high_impact	2,5	0,87	0,9	27,86	7,23	N	0,42	N	0,85	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13021	13021	C	G	MI.20711	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	685	229	L	V	Ctc/Gtc	-10,83	0	0	probably_damaging	1	neutral	0,53	neutral	4,23	neutral	-2,86	deleterious	-2,79	high_impact	4,59	damaging	0,44	damaging	0,04	deleterious	3,36	22,9	0,48	0,55	disease	0,74	neutral	0,48	disease	0,72	disease	0,64	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,26	high_impact	2,99	0,79	0,85	27,86	7,23	N	0,45	N	0,81	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13021	13021	C	T	MI.20712	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	685	229	L	F	Ctc/Ttc	-10,83	0	0	probably_damaging	1	neutral	0,72	neutral	4,55	neutral	-0,51	deleterious	-3,72	neutral_impact	0,46	damaging	0,44	damaging	0,07	deleterious	3,95	23,6	0,49	0,55	neutral	0,48	disease	0,5	disease	0,69	neutral	0,41	2	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,46	medium_impact	-0,78	0,69	0,85	27,86	7,23	N	0,29	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13022	13022	T	A	MI.20713	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	686	229	L	H	cTc/cAc	2,25	0,96	0	probably_damaging	1	neutral	0,56	neutral	4,11	deleterious	-6,72	deleterious	-6,51	high_impact	4,59	damaging	0,45	damaging	0,03	deleterious	4,01	23,6	0,18	0,45	disease	0,96	disease	0,69	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,29	high_impact	2,99	0,59	0,8	27,86	7,23	P	0,49	N	0,97	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13022	13022	T	C	MI.20714	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	686	229	L	P	cTc/cCc	2,25	0,96	0	probably_damaging	1	neutral	0,22	neutral	4,11	deleterious	-6,45	deleterious	-6,51	high_impact	4,59	damaging	0,43	damaging	0,03	deleterious	3,8	23,4	0,18	0,45	disease	0,96	disease	0,73	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,07	high_impact	2,99	0,58	0,8	27,86	7,23	P	0,5	N	0,99	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13022	13022	T	G	MI.20715	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	686	229	L	R	cTc/cGc	2,25	0,96	0	probably_damaging	1	neutral	0,36	neutral	4,11	deleterious	-6,27	deleterious	-5,58	high_impact	4,59	damaging	0,51	damaging	0,03	deleterious	4,08	23,7	0,18	0,45	disease	0,94	disease	0,79	disease	0,8	disease	0,8	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,1	high_impact	2,99	0,62	0,8	27,86	7,23	P	0,53	P	1	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13024	13024	C	G	MI.20716	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	688	230	H	D	Cac/Gac	-12,43	0	0	probably_damaging	1	neutral	0,22	neutral	3,98	deleterious	-5,97	deleterious	-8,37	high_impact	4,93	damaging	0,36	damaging	0,02	deleterious	3,78	23,4	0,33	0,5	disease	0,93	disease	0,76	disease	0,84	disease	0,77	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,07	high_impact	3,3	0,42	0,8	28,86	7,27	P	0,51	P	0,97	polymorphism	0,94	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13024	13024	C	A	MI.20717	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	688	230	H	N	Cac/Aac	-12,43	0	0	probably_damaging	1	neutral	0,32	neutral	4	deleterious	-5,09	deleterious	-6,51	high_impact	3,96	damaging	0,37	damaging	0,02	deleterious	3,82	23,4	0,47	0,55	disease	0,88	disease	0,74	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,05	high_impact	2,41	0,48	0,8	28,86	7,27	N	0,42	N	0,97	polymorphism	0,98	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13024	13024	C	T	MI.20718	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	688	230	H	Y	Cac/Tac	-12,43	0	0	probably_damaging	1	neutral	1	neutral	4,01	deleterious	-4,73	deleterious	-5,58	medium_impact	3,17	damaging	0,37	damaging	0,02	deleterious	3,63	23,2	0,41	0,5	disease	0,66	disease	0,76	disease	0,79	disease	0,72	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,83	low_impact	-3,6	high_impact	1,89	medium_impact	1,69	0,48	0,8	28,86	7,27	N	0,38	N	1	polymorphism	0,98	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13025	13025	A	T	MI.20719	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	689	230	H	L	cAc/cTc	4,31	0,99	0	probably_damaging	1	neutral	0,71	neutral	3,97	deleterious	-5,42	deleterious	-10,22	high_impact	4,12	damaging	0,38	damaging	0,02	deleterious	4,27	23,9	0,27	0,45	disease	0,73	disease	0,78	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,45	high_impact	2,56	0,37	0,8	28,86	7,27	P	0,65	P	0,97	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5997	5997	G	T	MI.2072	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	94	32	A	S	Gct/Tct	-12,13	0	0	probably_damaging	1	neutral	0,79	neutral	2,81	neutral	0,03	neutral	0,16	neutral_impact	-0,54	neutral	0,65	neutral	0,71	deleterious	0,8	9,48	0,38	0,55	neutral	0,36	neutral	0,1	neutral	0,23	neutral	0,27	5	deleterious	1	neutral	0,4	neutral	-2	deleterious	0,68	low_impact	-3,58	medium_impact	0,51	low_impact	-1,6	0,86	0,9	8,38	34,31	N	0,34	N	0,64	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13025	13025	A	C	MI.20720	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	689	230	H	P	cAc/cCc	4,31	0,99	0	probably_damaging	1	neutral	0,23	neutral	3,95	deleterious	-6,44	deleterious	-9,29	high_impact	4,58	damaging	0,34	damaging	0,04	deleterious	3,63	23,2	0,27	0,45	disease	0,96	disease	0,8	disease	0,78	disease	0,76	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,06	high_impact	2,98	0,39	0,8	28,86	7,27	P	0,65	P	0,97	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13025	13025	A	G	MI.20721	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	689	230	H	R	cAc/cGc	4,31	0,99	0	probably_damaging	1	neutral	0,37	neutral	3,99	deleterious	-5,56	deleterious	-7,44	high_impact	4,93	damaging	0,42	damaging	0,03	deleterious	3,41	23	0,49	0,55	disease	0,92	disease	0,75	disease	0,81	disease	0,76	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,11	high_impact	3,3	0,52	0,8	28,86	7,27	P	0,65	P	0,99	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13026	13026	C	G	MI.20722	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	690	230	H	Q	caC/caG	8,44	1	0	probably_damaging	1	neutral	0,31	neutral	4,04	deleterious	-4,12	deleterious	-7,44	medium_impact	3,06	damaging	0,42	damaging	0,02	deleterious	3,54	23,1	0,44	0,55	disease	0,82	disease	0,71	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,04	medium_impact	1,59	0,59	0,8	28,86	7,27	P	0,62	P	0,95	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13026	13026	C	A	MI.20723	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	690	230	H	Q	caC/caA	8,44	1	0	probably_damaging	1	neutral	0,31	neutral	4,04	deleterious	-4,12	deleterious	-7,44	medium_impact	3,06	damaging	0,42	damaging	0,02	deleterious	3,82	23,4	0,44	0,55	disease	0,82	disease	0,71	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,04	medium_impact	1,59	0,59	0,8	28,86	7,27	P	0,62	P	0,95	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13027	13027	C	A	MI.20724	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	691	231	P	T	Ccc/Acc	-0,73	0,04	0	probably_damaging	1	neutral	0,39	neutral	4,78	neutral	2,34	deleterious	-7,43	low_impact	1,78	damaging	0,51	damaging	0,05	deleterious	3,75	23,3	0,6	0,65	neutral	0,36	neutral	0,45	disease	0,69	neutral	0,44	1	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	0,13	medium_impact	0,42	0,8	0,85	29,68	7,2	N	0,27	N	0,91	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13027	13027	C	T	MI.20725	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	691	231	P	S	Ccc/Tcc	-0,73	0,04	0	probably_damaging	1	neutral	0,41	neutral	4,68	neutral	0,9	deleterious	-7,43	low_impact	1,81	damaging	0,5	damaging	0,04	deleterious	3,77	23,4	0,67	0,7	disease	0,55	disease	0,58	disease	0,62	disease	0,54	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,15	medium_impact	0,45	0,33	0,8	29,68	7,2	N	0,24	N	0,78	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13027	13027	C	G	MI.20726	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	691	231	P	A	Ccc/Gcc	-0,73	0,04	0	probably_damaging	1	neutral	0,54	neutral	4,72	neutral	0,57	deleterious	-7,43	low_impact	1,64	damaging	0,51	damaging	0,05	deleterious	2,99	22,2	0,56	0,6	neutral	0,37	neutral	0,44	disease	0,68	neutral	0,46	1	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,72	low_impact	-3,6	medium_impact	0,27	medium_impact	0,3	0,82	0,85	29,68	7,2	N	0,24	N	0,73	disease_causing	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13028	13028	C	G	MI.20727	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	692	231	P	R	cCc/cGc	7,07	1	0	probably_damaging	1	neutral	0,35	neutral	4,67	neutral	-0,87	deleterious	-8,37	high_impact	4,04	damaging	0,55	damaging	0,03	deleterious	3,56	23,1	0,54	0,6	disease	0,66	disease	0,72	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,08	high_impact	2,49	0,74	0,85	29,68	7,2	P	0,57	P	0,64	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13028	13028	C	T	MI.20728	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	692	231	P	L	cCc/cTc	7,07	1	0	probably_damaging	1	neutral	0,7	neutral	4,82	neutral	0,38	deleterious	-9,29	low_impact	1,78	damaging	0,52	damaging	0,03	deleterious	4,36	24,1	0,58	0,65	neutral	0,42	disease	0,65	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,44	medium_impact	0,42	0,82	0,85	29,68	7,2	N	0,38	N	0,97	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13028	13028	C	A	MI.20729	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	692	231	P	H	cCc/cAc	7,07	1	0	probably_damaging	1	neutral	0,56	neutral	4,63	neutral	-2,33	deleterious	-8,37	high_impact	3,69	damaging	0,5	damaging	0,02	deleterious	3,99	23,6	0,46	0,55	disease	0,88	disease	0,67	disease	0,76	disease	0,72	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,29	high_impact	2,17	0,75	0,85	29,68	7,2	P	0,52	P	0,72	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5998	5998	C	A	MI.2073	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	95	32	A	D	gCt/gAt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,72	deleterious	-3,42	neutral	-1,69	high_impact	3,77	neutral	0,64	neutral	0,37	deleterious	4,4	24,1	0,12	0,55	disease	0,76	disease	0,86	disease	0,66	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,38	0,73	0,9	8,38	34,31	P	0,54	P	0,89	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13030	13030	T	C	MI.20730	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	694	232	W	R	Tga/Cga	-10,6	0	0	probably_damaging	1	neutral	0,37	neutral	0,43	deleterious	-12,85	deleterious	-13,01	high_impact	4,68	damaging	0,47	damaging	0,04	deleterious	3,47	23,1	0,29	0,45	disease	0,99	disease	0,83	disease	0,85	disease	0,73	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,11	high_impact	3,07	0,17	0,8	28,52	7,25	N	0,41	N	0,97	polymorphism	0,97	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13030	13030	T	G	MI.20731	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	694	232	W	G	Tga/Gga	-10,6	0	0	probably_damaging	1	neutral	0,35	neutral	0,43	deleterious	-11,95	deleterious	-12,08	high_impact	5,23	damaging	0,44	damaging	0,05	deleterious	3,84	23,4	0,24	0,45	disease	0,99	disease	0,71	disease	0,82	disease	0,77	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,08	high_impact	3,57	0,17	0,8	28,52	7,25	N	0,42	N	0,97	polymorphism	0,92	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13031	13031	G	C	MI.20732	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	695	232	W	S	tGa/tCa	7,3	1	0	probably_damaging	1	neutral	0,43	neutral	0,43	deleterious	-12,98	deleterious	-13,01	high_impact	4,88	damaging	0,44	damaging	0,06	deleterious	3,95	23,6	0,23	0,45	disease	0,98	disease	0,84	disease	0,81	disease	0,72	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,17	high_impact	3,26	0,16	0,8	28,52	7,25	P	0,52	P	0,95	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13031	13031	G	T	MI.20733	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	695	232	W	L	tGa/tTa	7,3	1	0	probably_damaging	1	neutral	0,71	neutral	0,43	deleterious	-11,93	deleterious	-12,08	high_impact	5,23	damaging	0,44	damaging	0,03	deleterious	4,17	23,8	0,2	0,45	disease	0,68	disease	0,71	disease	0,81	disease	0,69	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,45	high_impact	3,57	0,2	0,8	28,52	7,25	P	0,55	P	0,97	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13032	13032	A	C	MI.20734	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	696	232	W	C	tgA/tgC	8,9	1	0	probably_damaging	1	neutral	0,17	neutral	0,43	deleterious	-13,81	deleterious	-12,08	high_impact	4,88	damaging	0,41	damaging	0,03	deleterious	3,92	23,5	0,28	0,45	disease	0,99	disease	0,81	disease	0,85	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,15	high_impact	3,26	0,17	0,8	28,52	7,25	P	0,56	P	0,98	disease_causing	1	0,44	rs386829172	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13032	13032	A	T	MI.20735	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	696	232	W	C	tgA/tgT	8,9	1	0	probably_damaging	1	neutral	0,17	neutral	0,43	deleterious	-13,81	deleterious	-12,08	high_impact	4,88	damaging	0,41	damaging	0,03	deleterious	4,04	23,7	0,28	0,45	disease	0,99	disease	0,81	disease	0,85	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,15	high_impact	3,26	0,17	0,8	28,52	7,25	P	0,56	P	0,98	disease_causing	1	0,44	rs386829172	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13033	13033	C	G	MI.20736	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	697	233	L	V	Ctc/Gtc	2,02	1	0	probably_damaging	1	neutral	0,52	neutral	4,04	deleterious	-4,37	deleterious	-2,79	high_impact	5,24	damaging	0,31	damaging	0,14	deleterious	3,35	22,9	0,49	0,55	disease	0,79	neutral	0,36	disease	0,6	disease	0,59	2	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,25	high_impact	3,58	0,74	0,85	26,87	7,27	P	0,72	P	0,81	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13033	13033	C	T	MI.20737	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	697	233	L	F	Ctc/Ttc	2,02	1	0	probably_damaging	1	neutral	0,83	neutral	4	deleterious	-6,51	deleterious	-3,72	high_impact	4,89	damaging	0,3	damaging	0,12	deleterious	3,94	23,5	0,41	0,5	disease	0,93	neutral	0,44	disease	0,62	disease	0,62	2	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,61	high_impact	3,26	0,7	0,85	26,87	7,27	P	0,66	P	0,99	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13033	13033	C	A	MI.20738	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	697	233	L	I	Ctc/Atc	2,02	1	0	probably_damaging	1	neutral	0,47	neutral	4,1	deleterious	-4,96	neutral	-1,86	high_impact	4,89	damaging	0,31	damaging	0,15	deleterious	4,01	23,6	0,38	0,5	disease	0,87	neutral	0,39	disease	0,67	disease	0,62	2	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,2	high_impact	3,26	0,77	0,85	26,87	7,27	P	0,79	P	0,85	disease_causing	0,99	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13034	13034	T	A	MI.20739	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	698	233	L	H	cTc/cAc	0,87	1	0	probably_damaging	1	neutral	0,55	neutral	3,93	deleterious	-7,57	deleterious	-6,5	high_impact	5,24	damaging	0,33	damaging	0,13	deleterious	4,26	23,9	0,23	0,45	disease	0,97	disease	0,6	disease	0,76	disease	0,74	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,28	high_impact	3,58	0,62	0,8	26,87	7,27	P	0,65	P	0,97	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5998	5998	C	T	MI.2074	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	95	32	A	V	gCt/gTt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,98	neutral	1,5	neutral	-1,8	medium_impact	1,98	neutral	0,63	neutral	0,46	deleterious	4,21	23,9	0,29	0,55	neutral	0,2	disease	0,61	neutral	0,31	neutral	0,46	1	deleterious	1	neutral	0	deleterious	5	deleterious	0,69	low_impact	-3,58	low_impact	-1,48	medium_impact	0,73	0,87	0,9	8,38	34,31	P	0,58	P	0,75	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13034	13034	T	G	MI.20740	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	698	233	L	R	cTc/cGc	0,87	1	0	probably_damaging	1	neutral	0,36	neutral	3,93	deleterious	-7,08	deleterious	-5,58	high_impact	5,24	damaging	0,39	damaging	0,13	deleterious	4,15	23,8	0,21	0,45	disease	0,96	disease	0,68	disease	0,78	disease	0,76	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,1	high_impact	3,58	0,59	0,8	26,87	7,27	P	0,7	P	1	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13034	13034	T	C	MI.20741	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	698	233	L	P	cTc/cCc	0,87	1	0	probably_damaging	1	neutral	0,27	neutral	3,93	deleterious	-8,04	deleterious	-6,5	high_impact	4,69	damaging	0,32	damaging	0,13	deleterious	3,89	23,5	0,21	0,45	disease	0,78	disease	0,57	disease	0,68	disease	0,67	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,01	high_impact	3,08	0,57	0,8	26,87	7,27	P	0,64	P	0,99	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13036	13036	C	T	MI.20742	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	700	234	P	S	Ccc/Tcc	-20	0	0	probably_damaging	1	neutral	0,42	neutral	4,1	deleterious	-5,74	deleterious	-7,44	high_impact	3,62	damaging	0,51	damaging	0,03	deleterious	3,85	23,4	0,23	0,45	disease	0,89	disease	0,63	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,16	high_impact	2,1	0,25	0,8	28,03	7,19	N	0,25	N	0,78	polymorphism	0,97	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13036	13036	C	A	MI.20743	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	700	234	P	T	Ccc/Acc	-20	0	0	probably_damaging	1	neutral	0,39	neutral	4,14	deleterious	-5,7	deleterious	-7,44	medium_impact	3,17	damaging	0,51	damaging	0,02	deleterious	3,65	23,2	0,26	0,45	disease	0,68	disease	0,66	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,13	medium_impact	1,69	0,44	0,8	28,03	7,19	N	0,22	N	0,91	polymorphism	0,98	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13036	13036	C	G	MI.20744	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	700	234	P	A	Ccc/Gcc	-20	0	0	probably_damaging	1	neutral	0,53	neutral	4,16	deleterious	-4,66	deleterious	-7,44	medium_impact	2,91	damaging	0,4	damaging	0,19	deleterious	3,06	22,4	0,2	0,45	disease	0,84	neutral	0,44	disease	0,64	disease	0,6	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,26	medium_impact	1,46	0,54	0,8	28,03	7,19	N	0,37	N	0,73	polymorphism	0,98	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13037	13037	C	A	MI.20745	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	701	234	P	H	cCc/cAc	5,23	1	0	probably_damaging	1	neutral	0,54	neutral	4,08	deleterious	-7,62	deleterious	-8,37	high_impact	5,07	damaging	0,51	damaging	0,02	deleterious	4,03	23,6	0,2	0,45	disease	0,95	disease	0,71	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,27	high_impact	3,43	0,5	0,8	28,03	7,19	P	0,55	P	0,72	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13037	13037	C	G	MI.20746	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	701	234	P	R	cCc/cGc	5,23	1	0	probably_damaging	1	neutral	0,35	neutral	4,09	deleterious	-6,59	deleterious	-8,37	high_impact	5,07	damaging	0,56	damaging	0,03	deleterious	3,59	23,2	0,18	0,45	disease	0,88	disease	0,74	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,08	high_impact	3,43	0,47	0,8	28,03	7,19	P	0,59	P	0,64	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13037	13037	C	T	MI.20747	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	701	234	P	L	cCc/cTc	5,23	1	0	probably_damaging	1	neutral	0,7	neutral	4,22	deleterious	-4,52	deleterious	-9,29	medium_impact	3,31	damaging	0,46	damaging	0,02	deleterious	4,4	24,1	0,26	0,45	disease	0,88	disease	0,67	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,44	medium_impact	1,82	0,71	0,85	28,03	7,19	N	0,46	N	0,97	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13039	13039	T	C	MI.20748	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	703	235	S	P	Tca/Cca	-6,47	0	0	probably_damaging	1	neutral	0,25	neutral	4,6	neutral	-2,02	deleterious	-4,48	medium_impact	2,38	neutral	0,6	damaging	0,11	deleterious	3,95	23,6	0,41	0,5	disease	0,87	disease	0,71	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,03	medium_impact	0,97	0,44	0,8	9,12	7,13	N	0,22	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13039	13039	T	G	MI.20749	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	703	235	S	A	Tca/Gca	-6,47	0	0	probably_damaging	1	neutral	0,57	neutral	4,66	neutral	0,2	neutral	-2,46	neutral_impact	-1,32	neutral	0,76	neutral	0,5	deleterious	2,5	19,46	0,54	0,6	disease	0,54	neutral	0,07	neutral	0,17	neutral	0,29	4	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	0,3	low_impact	-2,41	0,7	0,85	9,12	7,13	N	0,31	N	0,49	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	5998	5998	C	G	MI.2075	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	95	32	A	G	gCt/gGt	6,14	1	0	probably_damaging	0,99	neutral	0,35	neutral	2,74	neutral	-1,79	neutral	-0,97	low_impact	1,01	neutral	0,7	neutral	0,91	deleterious	2,5	19,5	0,21	0,55	disease	0,62	neutral	0,46	neutral	0,29	disease	0,61	2	deleterious	0,99	neutral	0,18	neutral	-2	deleterious	0,74	low_impact	-2,64	medium_impact	0,04	medium_impact	-0,17	0,81	0,9	8,38	34,31	P	0,58	P	0,56	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13039	13039	T	A	MI.20750	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	703	235	S	T	Tca/Aca	-6,47	0	0	probably_damaging	1	neutral	0,42	neutral	4,66	neutral	0,07	deleterious	-2,68	medium_impact	1,97	neutral	0,71	damaging	0,11	deleterious	3,75	23,3	0,47	0,55	neutral	0,48	neutral	0,39	neutral	0,41	neutral	0,43	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,7	low_impact	-3,6	medium_impact	0,16	medium_impact	0,6	0,63	0,8	9,12	7,13	N	0,26	N	0,71	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13040	13040	C	G	MI.20751	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	704	235	S	W	tCa/tGa	2,48	0,98	0	probably_damaging	1	neutral	0,19	neutral	4,56	deleterious	-4,05	deleterious	-6,34	medium_impact	2,52	neutral	0,72	damaging	0,1	deleterious	4,32	24	0,28	0,45	disease	0,97	disease	0,68	disease	0,64	disease	0,76	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	-0,12	medium_impact	1,1	0,57	0,8	9,12	7,13	N	0,36	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13040	13040	C	T	MI.20752	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	704	235	S	L	tCa/tTa	2,48	0,98	0	probably_damaging	1	neutral	0,73	neutral	4,59	neutral	-1,18	deleterious	-5,36	low_impact	1,68	neutral	0,71	damaging	0,07	deleterious	4,62	24,5	0,42	0,55	disease	0,67	disease	0,56	disease	0,55	disease	0,62	2	deleterious	1	neutral	0,37	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	0,47	medium_impact	0,33	0,81	0,85	9,12	7,13	N	0,32	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13042	13042	G	A	MI.20753	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	706	236	A	T	Gcc/Acc	-8,99	0	0	probably_damaging	1	neutral	0,42	neutral	4,12	deleterious	-4,58	deleterious	-3,72	high_impact	4,87	damaging	0,25	damaging	0,19	deleterious	4,2	23,9	0,33	0,5	disease	0,61	disease	0,56	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,16	high_impact	3,25	0,72	0,85	28,69	7,16	P	0,85	P	0,94	disease_causing_automatic	0,03	0,22	rs267606898	Pathogenic|Pathogenic|Pathogenic	Juvenile_myopathy,_encephalopathy,_lactic_acidosis_AND_stroke|Myoclonus_with_epilepsy_with_ragged_red_fibers|Leigh_syndrome_due_to_mitochondrial_complex_I_deficiency	RCV000010347.2|RCV000010348.3|RCV000010349.3	MedGen:OMIM:Orphanet:SNOMED_CT|MedGen:OMIM:Orphanet|MedGen	.	COSM5652748	.	.	G13042A	Optic neuropathy/retinopathy/LD	-	+	Reported	5
chrM	13042	13042	G	C	MI.20754	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	706	236	A	P	Gcc/Ccc	-8,99	0	0	probably_damaging	1	neutral	0,24	neutral	4,02	deleterious	-6,89	deleterious	-4,65	high_impact	4,41	damaging	0,27	damaging	0,27	deleterious	3,84	23,4	0,24	0,45	disease	0,86	disease	0,59	disease	0,83	disease	0,73	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,04	high_impact	2,83	0,6	0,8	28,69	7,16	P	0,83	P	0,96	polymorphism	0,9	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13042	13042	G	T	MI.20755	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	706	236	A	S	Gcc/Tcc	-8,99	0	0	probably_damaging	1	neutral	0,45	neutral	4,23	deleterious	-4,3	deleterious	-2,79	high_impact	3,64	damaging	0,32	neutral	0,39	deleterious	3,68	23,3	0,22	0,45	disease	0,76	disease	0,51	disease	0,71	disease	0,64	3	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,18	high_impact	2,12	0,69	0,85	28,69	7,16	P	0,62	P	0,98	polymorphism	0,99	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13043	13043	C	T	MI.20756	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	707	236	A	V	gCc/gTc	8,9	1	0	probably_damaging	1	neutral	0,52	neutral	4,37	neutral	-2,93	deleterious	-3,72	high_impact	4,32	damaging	0,15	damaging	0,24	deleterious	4,4	24,1	0,42	0,55	disease	0,67	disease	0,56	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,25	high_impact	2,74	0,76	0,85	28,69	7,16	P	0,96	P	0,76	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13043	13043	C	A	MI.20757	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	707	236	A	D	gCc/gAc	8,9	1	0	probably_damaging	1	neutral	0,23	neutral	4,01	deleterious	-7,24	deleterious	-5,58	high_impact	5,21	damaging	0,35	neutral	0,32	deleterious	4,59	24,4	0,2	0,45	disease	0,97	disease	0,7	disease	0,82	disease	0,76	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,06	high_impact	3,56	0,61	0,8	28,69	7,16	P	0,8	P	0,95	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13043	13043	C	G	MI.20758	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	707	236	A	G	gCc/gGc	8,9	1	0	probably_damaging	1	neutral	0,36	neutral	4,03	deleterious	-6,06	deleterious	-3,72	high_impact	5,21	damaging	0,28	neutral	0,38	deleterious	3,93	23,5	0,27	0,45	disease	0,93	neutral	0,37	disease	0,74	disease	0,66	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,1	high_impact	3,56	0,72	0,85	28,69	7,16	P	0,93	P	0,82	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13045	13045	A	T	MI.20759	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	709	237	M	L	Ata/Tta	-8,99	0	0	probably_damaging	0,98	neutral	0,75	neutral	4,53	deleterious	-3,43	deleterious	-2,79	high_impact	5,22	damaging	0,44	damaging	0,06	deleterious	3,46	23	0,29	0,45	disease	0,76	disease	0,53	disease	0,77	disease	0,72	4	deleterious	0,98	neutral	0,39	deleterious	2	deleterious	0,69	low_impact	-2,35	medium_impact	0,5	high_impact	3,57	0,35	0,8	27,86	7,11	P	0,7	P	0,98	disease_causing_automatic	0	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6000	6000	C	G	MI.2076	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	97	33	L	V	Cta/Gta	-10,05	0	0	benign	0,19	deleterious	0,01	neutral	2,62	neutral	-1,59	neutral	-1,3	high_impact	3,81	damaging	0,55	neutral	0,42	neutral	1,57	13,67	0,42	0,55	neutral	0,41	disease	0,52	disease	0,56	disease	0,58	2	deleterious	0,99	neutral	0,41	deleterious	2	neutral	0,24	medium_impact	-0,16	medium_impact	-0,92	high_impact	2,42	0,75	0,9	10,14	39,34	N	0,44	N	0,66	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13045	13045	A	C	MI.20760	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	709	237	M	L	Ata/Cta	-8,99	0	0	probably_damaging	0,98	neutral	0,75	neutral	4,53	deleterious	-3,43	deleterious	-2,79	high_impact	5,22	damaging	0,44	damaging	0,06	deleterious	3,31	22,9	0,29	0,45	disease	0,76	disease	0,53	disease	0,77	disease	0,72	4	deleterious	0,98	neutral	0,39	deleterious	2	deleterious	0,69	low_impact	-2,35	medium_impact	0,5	high_impact	3,57	0,35	0,8	27,86	7,11	P	0,73	P	0,98	disease_causing_automatic	0	0,27	rs267606895	Pathogenic|Pathogenic|Pathogenic	Juvenile_myopathy,_encephalopathy,_lactic_acidosis_AND_stroke|Leber's_optic_atrophy|Leigh_syndrome_due_to_mitochondrial_complex_I_deficiency	RCV000010340.2|RCV000010341.2|RCV000010342.3	MedGen:OMIM:Orphanet:SNOMED_CT|MedGen:OMIM:SNOMED_CT|MedGen	.	.	.	.	A13045C	MELAS/LHON/Leigh overlap syndrome	-	+	Reported	4
chrM	13045	13045	A	G	MI.20761	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	709	237	M	V	Ata/Gta	-8,99	0	0	probably_damaging	0,99	neutral	0,57	neutral	4,48	neutral	-2,15	deleterious	-3,72	high_impact	5,22	damaging	0,42	damaging	0,09	deleterious	2,77	21,2	0,36	0,5	disease	0,77	disease	0,6	disease	0,8	disease	0,7	4	deleterious	0,99	neutral	0,29	deleterious	2	deleterious	0,72	low_impact	-2,64	medium_impact	0,3	high_impact	3,57	0,35	0,8	27,86	7,11	P	0,68	P	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13046	13046	T	A	MI.20762	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	710	237	M	K	aTa/aAa	6,61	1	0	probably_damaging	1	neutral	0,55	neutral	4,41	deleterious	-5,47	deleterious	-5,58	high_impact	4,88	damaging	0,48	damaging	0,09	deleterious	3,93	23,5	0,28	0,45	disease	0,93	disease	0,69	disease	0,84	disease	0,77	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,28	high_impact	3,26	0,28	0,8	27,86	7,11	P	0,75	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13046	13046	T	C	MI.20763	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	710	237	M	T	aTa/aCa	6,61	1	0	probably_damaging	1	neutral	0,58	neutral	4,46	deleterious	-3,88	deleterious	-5,58	high_impact	4,88	damaging	0,49	damaging	0,09	deleterious	2,94	22	0,37	0,5	disease	0,83	disease	0,69	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,31	high_impact	3,26	0,26	0,8	27,86	7,11	P	0,72	P	0,99	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13047	13047	A	C	MI.20764	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	711	237	M	I	atA/atC	5,69	1	0	probably_damaging	0,99	neutral	0,45	neutral	4,49	deleterious	-3,84	deleterious	-3,72	high_impact	4,08	damaging	0,46	damaging	0,11	deleterious	3,37	22,9	0,44	0,55	disease	0,8	disease	0,61	disease	0,8	disease	0,71	4	deleterious	0,99	neutral	0,23	deleterious	2	deleterious	0,78	low_impact	-2,64	medium_impact	0,18	high_impact	2,52	0,4	0,8	27,86	7,11	P	0,7	P	0,94	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13047	13047	A	T	MI.20765	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	711	237	M	I	atA/atT	5,69	1	0	probably_damaging	0,99	neutral	0,45	neutral	4,49	deleterious	-3,84	deleterious	-3,72	high_impact	4,08	damaging	0,46	damaging	0,11	deleterious	3,45	23	0,44	0,55	disease	0,8	disease	0,61	disease	0,8	disease	0,71	4	deleterious	0,99	neutral	0,23	deleterious	2	deleterious	0,78	low_impact	-2,64	medium_impact	0,18	high_impact	2,52	0,4	0,8	27,86	7,11	P	0,71	P	0,94	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13048	13048	G	C	MI.20766	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	712	238	E	Q	Gaa/Caa	3,85	1	0	probably_damaging	1	neutral	0,39	neutral	4,45	neutral	-2,15	deleterious	-2,79	high_impact	4	damaging	0,32	damaging	0,06	deleterious	3,29	22,8	0,56	0,6	disease	0,81	disease	0,57	disease	0,57	disease	0,64	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,13	high_impact	2,45	0,68	0,85	29,19	7,13	P	0,65	P	0,89	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13048	13048	G	A	MI.20767	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	712	238	E	K	Gaa/Aaa	3,85	1	0	probably_damaging	1	neutral	0,45	neutral	4,41	deleterious	-3,28	deleterious	-3,72	high_impact	3,92	damaging	0,3	damaging	0,03	deleterious	4,47	24,2	0,49	0,55	disease	0,79	disease	0,68	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,18	high_impact	2,38	0,64	0,8	29,19	7,13	P	0,73	P	0,99	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13049	13049	A	G	MI.20768	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	713	238	E	G	gAa/gGa	8,9	1	0	probably_damaging	1	neutral	0,41	neutral	4,37	deleterious	-4,32	deleterious	-6,51	high_impact	4,81	damaging	0,32	damaging	0,11	deleterious	4,16	23,8	0,57	0,65	disease	0,87	neutral	0,5	disease	0,56	disease	0,63	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,15	high_impact	3,19	0,52	0,8	29,19	7,13	P	0,74	P	0,51	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13049	13049	A	C	MI.20769	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	713	238	E	A	gAa/gCa	8,9	1	0	probably_damaging	1	neutral	0,65	neutral	4,44	neutral	-1,68	deleterious	-5,58	low_impact	1,92	damaging	0,32	damaging	0,09	deleterious	3,56	23,1	0,54	0,6	disease	0,68	disease	0,5	disease	0,58	disease	0,57	1	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,38	medium_impact	0,55	0,72	0,85	29,19	7,13	P	0,67	P	0,75	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6000	6000	C	A	MI.2077	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	97	33	L	M	Cta/Ata	-10,05	0	0	benign	0,11	neutral	0,15	neutral	2,63	neutral	-1,41	neutral	-0,38	low_impact	0,85	damaging	0,57	neutral	0,68	deleterious	0,43	6,91	0,34	0,55	neutral	0,42	neutral	0,14	neutral	0,27	neutral	0,28	4	neutral	0,83	deleterious	0,52	neutral	-6	neutral	0,17	medium_impact	0,1	medium_impact	-0,23	medium_impact	-0,31	0,64	0,9	10,14	39,34	P	0,54	P	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13049	13049	A	T	MI.20770	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	713	238	E	V	gAa/gTa	8,9	1	0	probably_damaging	1	neutral	0,56	neutral	4,54	deleterious	-3,29	deleterious	-6,51	medium_impact	3,16	damaging	0,28	damaging	0,06	deleterious	4,04	23,7	0,45	0,55	disease	0,86	disease	0,72	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,29	medium_impact	1,68	0,75	0,85	29,19	7,13	P	0,79	P	0,81	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13050	13050	A	C	MI.20771	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	714	238	E	D	gaA/gaC	8,44	1	0,01	probably_damaging	1	neutral	0,31	neutral	4,37	deleterious	-3,88	deleterious	-2,79	high_impact	4,46	damaging	0,3	damaging	0,05	deleterious	3,68	23,3	0,52	0,6	disease	0,87	disease	0,53	disease	0,54	disease	0,6	2	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,04	high_impact	2,87	0,69	0,85	29,19	7,13	P	0,7	P	0,86	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13050	13050	A	T	MI.20772	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	714	238	E	D	gaA/gaT	8,44	1	0,01	probably_damaging	1	neutral	0,31	neutral	4,37	deleterious	-3,88	deleterious	-2,79	high_impact	4,46	damaging	0,3	damaging	0,05	deleterious	3,81	23,4	0,52	0,6	disease	0,87	disease	0,53	disease	0,54	disease	0,6	2	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,04	high_impact	2,87	0,69	0,85	29,19	7,13	P	0,7	P	0,86	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13051	13051	G	A	MI.20773	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	715	239	G	S	Ggc/Agc	1,33	1	0	probably_damaging	1	neutral	0,42	neutral	4,44	deleterious	-3,07	deleterious	-5,35	high_impact	4,2	damaging	0,38	damaging	0,03	deleterious	4,23	23,9	0,47	0,55	disease	0,78	disease	0,66	disease	0,68	disease	0,67	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,16	high_impact	2,63	0,73	0,85	29,02	7,26	P	0,71	P	1	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	G13051A	LHON	+	-	Cfrm	2
chrM	13051	13051	G	T	MI.20774	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	715	239	G	C	Ggc/Tgc	1,33	1	0	probably_damaging	1	neutral	0,18	neutral	4,32	deleterious	-6,79	deleterious	-8,03	high_impact	4,89	damaging	0,29	damaging	0,02	deleterious	4,1	23,7	0,37	0,5	disease	0,96	disease	0,74	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,13	high_impact	3,26	0,46	0,8	29,02	7,26	P	0,7	P	0,97	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13051	13051	G	C	MI.20775	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	715	239	G	R	Ggc/Cgc	1,33	1	0	probably_damaging	1	neutral	0,35	neutral	4,38	deleterious	-4,05	deleterious	-7,13	high_impact	4,89	damaging	0,35	damaging	0,02	deleterious	3,95	23,6	0,5	0,6	disease	0,87	disease	0,73	disease	0,79	disease	0,73	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,08	high_impact	3,26	0,8	0,85	29,02	7,26	P	0,7	P	1	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13052	13052	G	T	MI.20776	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	716	239	G	V	gGc/gTc	8,9	1	0	probably_damaging	1	neutral	0,52	neutral	4,35	deleterious	-4,89	deleterious	-8,03	high_impact	4,89	damaging	0,31	damaging	0,02	deleterious	3,74	23,3	0,45	0,55	disease	0,81	disease	0,74	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,25	high_impact	3,26	0,55	0,8	29,02	7,26	P	0,66	P	0,98	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13052	13052	G	A	MI.20777	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	716	239	G	D	gGc/gAc	8,9	1	0	probably_damaging	1	neutral	0,21	neutral	4,38	deleterious	-4,2	deleterious	-6,24	high_impact	4,89	damaging	0,27	damaging	0,02	deleterious	3,89	23,5	0,47	0,55	disease	0,92	disease	0,76	disease	0,79	disease	0,79	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,09	high_impact	3,26	0,39	0,8	29,02	7,26	P	0,83	P	0,95	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13052	13052	G	C	MI.20778	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	716	239	G	A	gGc/gCc	8,9	1	0	probably_damaging	1	neutral	0,51	neutral	4,46	neutral	0,08	deleterious	-5,35	medium_impact	1,98	damaging	0,38	damaging	0,03	deleterious	3,07	22,4	0,61	0,65	neutral	0,4	neutral	0,5	disease	0,64	disease	0,55	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,24	medium_impact	0,61	0,62	0,8	29,02	7,26	P	0,6	P	0,79	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13054	13054	C	A	MI.20779	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	718	240	P	T	Ccc/Acc	-3,49	0	0	probably_damaging	1	neutral	0,42	neutral	4,46	deleterious	-5,6	deleterious	-7,13	high_impact	4,88	damaging	0,32	neutral	0,3	deleterious	3,63	23,2	0,31	0,5	disease	0,8	disease	0,59	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,16	high_impact	3,26	0,5	0,8	26,87	7,18	P	0,65	P	0,91	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6001	6001	T	C	MI.2078	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	98	33	L	P	cTa/cCa	-1,26	0	0	probably_damaging	0,97	deleterious	0	neutral	2,53	deleterious	-4,36	deleterious	-3,34	high_impact	4,62	damaging	0,5	neutral	0,36	deleterious	3,68	23,3	0,15	0,55	disease	0,72	disease	0,87	disease	0,69	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-2,18	low_impact	-1,48	high_impact	3,17	0,56	0,9	10,14	39,34	N	0,5	N	0,83	disease_causing	0,87	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13054	13054	C	G	MI.20780	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	718	240	P	A	Ccc/Gcc	-3,49	0	0	probably_damaging	1	neutral	0,54	neutral	4,68	deleterious	-4,4	deleterious	-7,13	high_impact	4,34	damaging	0,32	neutral	0,43	deleterious	3	22,2	0,29	0,45	disease	0,82	neutral	0,41	disease	0,67	disease	0,61	2	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,27	high_impact	2,76	0,73	0,85	26,87	7,18	P	0,64	P	0,73	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13054	13054	C	T	MI.20781	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	718	240	P	S	Ccc/Tcc	-3,49	0	0	probably_damaging	1	neutral	0,46	neutral	4,55	deleterious	-5,08	deleterious	-7,13	high_impact	4,68	damaging	0,35	neutral	0,4	deleterious	3,89	23,5	0,36	0,5	disease	0,69	disease	0,6	disease	0,67	disease	0,65	3	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,19	high_impact	3,07	0,22	0,8	26,87	7,18	P	0,61	P	0,78	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13055	13055	C	A	MI.20782	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	719	240	P	H	cCc/cAc	7,07	1	0	probably_damaging	1	neutral	0,55	neutral	4,43	deleterious	-7,25	deleterious	-8,03	high_impact	4,88	damaging	0,33	damaging	0,27	deleterious	4,01	23,6	0,26	0,45	disease	0,87	disease	0,66	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,28	high_impact	3,26	0,49	0,8	26,87	7,18	P	0,75	P	0,72	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13055	13055	C	G	MI.20783	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	719	240	P	R	cCc/cGc	7,07	1	0	probably_damaging	1	neutral	0,34	neutral	4,44	deleterious	-6,26	deleterious	-8,03	high_impact	5,23	damaging	0,36	neutral	0,31	deleterious	3,57	23,2	0,22	0,45	disease	0,89	disease	0,67	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,07	high_impact	3,57	0,44	0,8	26,87	7,18	P	0,77	P	0,64	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13055	13055	C	T	MI.20784	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	719	240	P	L	cCc/cTc	7,07	1	0	probably_damaging	1	neutral	0,69	neutral	4,65	deleterious	-6,03	deleterious	-8,92	high_impact	4,88	damaging	0,25	neutral	0,34	deleterious	4,39	24,1	0,27	0,45	disease	0,88	disease	0,62	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,42	high_impact	3,26	0,57	0,8	26,87	7,18	P	0,85	P	0,97	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13057	13057	A	C	MI.20785	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	721	241	T	P	Acc/Ccc	-20	0	0	probably_damaging	1	neutral	0,24	neutral	4,69	deleterious	-4,5	deleterious	-5,35	high_impact	5,21	damaging	0,35	neutral	0,33	deleterious	4	23,6	0,32	0,5	disease	0,9	neutral	0,47	disease	0,69	disease	0,64	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	-0,04	high_impact	3,56	0,31	0,8	28,86	7,2	P	0,61	P	0,97	disease_causing	0,51	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13057	13057	A	G	MI.20786	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	721	241	T	A	Acc/Gcc	-20	0	0	probably_damaging	1	neutral	0,54	neutral	4,47	deleterious	-3,26	deleterious	-4,46	high_impact	4,11	damaging	0,36	neutral	0,48	deleterious	4,01	23,6	0,46	0,55	disease	0,79	neutral	0,29	disease	0,69	disease	0,55	1	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,73	low_impact	-3,6	medium_impact	0,27	high_impact	2,55	0,28	0,8	28,86	7,2	P	0,57	P	0,69	polymorphism	0,83	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13057	13057	A	T	MI.20787	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	721	241	T	S	Acc/Tcc	-20	0	0	probably_damaging	1	neutral	0,48	neutral	4,55	neutral	-2,83	deleterious	-3,57	high_impact	3,89	damaging	0,4	neutral	0,48	deleterious	3,86	23,5	0,46	0,55	disease	0,59	neutral	0,37	disease	0,62	disease	0,56	1	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,72	low_impact	-3,6	medium_impact	0,21	high_impact	2,35	0,33	0,8	28,86	7,2	P	0,55	P	0,89	polymorphism	0,94	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13058	13058	C	G	MI.20788	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	722	241	T	S	aCc/aGc	8,44	1	0	probably_damaging	1	neutral	0,48	neutral	4,55	neutral	-2,83	deleterious	-3,57	high_impact	3,89	damaging	0,4	neutral	0,48	deleterious	3,52	23,1	0,46	0,55	disease	0,59	neutral	0,37	disease	0,62	disease	0,56	1	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,72	low_impact	-3,6	medium_impact	0,21	high_impact	2,35	0,33	0,8	28,86	7,2	P	0,76	P	0,89	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13058	13058	C	A	MI.20789	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	722	241	T	N	aCc/aAc	8,44	1	0	probably_damaging	1	neutral	0,31	neutral	4,47	deleterious	-4,89	deleterious	-4,46	high_impact	4,17	damaging	0,29	neutral	0,41	deleterious	3,64	23,2	0,52	0,6	disease	0,84	neutral	0,48	disease	0,71	disease	0,67	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,75	low_impact	-3,6	medium_impact	0,04	high_impact	2,61	0,48	0,8	28,86	7,2	P	0,92	P	0,93	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6001	6001	T	A	MI.2079	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	98	33	L	Q	cTa/cAa	-1,26	0	0	possibly_damaging	0,88	deleterious	0	neutral	2,55	deleterious	-3,33	deleterious	-2,65	high_impact	4,26	damaging	0,57	neutral	0,42	deleterious	3,76	23,3	0,16	0,55	neutral	0,5	disease	0,76	disease	0,56	disease	0,67	3	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,69	low_impact	-1,57	low_impact	-1,48	high_impact	2,83	0,62	0,9	10,14	39,34	N	0,42	N	0,82	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13058	13058	C	T	MI.20790	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	722	241	T	I	aCc/aTc	8,44	1	0	probably_damaging	1	neutral	0,41	neutral	4,5	deleterious	-5,53	deleterious	-5,35	high_impact	4,41	damaging	0,35	neutral	0,49	deleterious	3,97	23,6	0,4	0,5	disease	0,75	disease	0,58	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,15	high_impact	2,83	0,38	0,8	28,86	7,2	P	0,75	P	0,95	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13060	13060	C	A	MI.20791	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	724	242	P	T	Cca/Aca	-11,74	0	0	probably_damaging	1	neutral	0,44	neutral	4,55	deleterious	-3,96	deleterious	-7,21	high_impact	3,98	damaging	0,32	neutral	0,3	deleterious	3,7	23,3	0,45	0,55	disease	0,77	disease	0,58	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,18	high_impact	2,43	0,79	0,85	27,2	7,25	P	0,55	P	0,91	disease_causing	0,64	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13060	13060	C	G	MI.20792	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	724	242	P	A	Cca/Gca	-11,74	0	0	probably_damaging	1	neutral	0,57	neutral	4,45	neutral	-2,78	deleterious	-7,21	high_impact	4,54	damaging	0,32	neutral	0,43	deleterious	3,05	22,4	0,5	0,6	disease	0,66	neutral	0,38	disease	0,75	disease	0,63	3	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,74	low_impact	-3,6	medium_impact	0,3	high_impact	2,94	0,78	0,85	27,2	7,25	P	0,68	P	0,73	disease_causing	0,53	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13060	13060	C	T	MI.20793	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	724	242	P	S	Cca/Tca	-11,74	0	0	probably_damaging	1	neutral	0,47	neutral	4,4	deleterious	-3,79	deleterious	-7,21	high_impact	4,13	damaging	0,35	neutral	0,4	deleterious	3,89	23,5	0,55	0,6	disease	0,66	disease	0,62	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,2	high_impact	2,57	0,34	0,8	27,2	7,25	P	0,57	P	0,78	disease_causing	0,65	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13061	13061	C	T	MI.20794	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	725	242	P	L	cCa/cTa	7,07	1	0	probably_damaging	1	neutral	0,7	neutral	4,52	deleterious	-4,96	deleterious	-9,01	high_impact	5,23	damaging	0,25	neutral	0,34	deleterious	4,36	24,1	0,52	0,6	disease	0,7	disease	0,62	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,44	high_impact	3,57	0,72	0,85	27,2	7,25	P	0,87	P	0,97	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13061	13061	C	A	MI.20795	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	725	242	P	Q	cCa/cAa	7,07	1	0	probably_damaging	1	neutral	0,31	neutral	4,37	deleterious	-4,96	deleterious	-7,21	high_impact	5,23	damaging	0,36	neutral	0,33	deleterious	4,06	23,7	0,33	0,5	disease	0,91	disease	0,7	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,04	high_impact	3,57	0,76	0,85	27,2	7,25	P	0,79	P	0,85	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13061	13061	C	G	MI.20796	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	725	242	P	R	cCa/cGa	7,07	1	0	probably_damaging	1	neutral	0,36	neutral	4,38	deleterious	-5,34	deleterious	-8,11	high_impact	4,88	damaging	0,36	neutral	0,31	deleterious	3,56	23,1	0,38	0,5	disease	0,93	disease	0,66	disease	0,82	disease	0,74	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,1	high_impact	3,26	0,59	0,8	27,2	7,25	P	0,78	P	0,64	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13063	13063	G	A	MI.20797	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	727	243	V	I	Gtc/Atc	-9,22	0	0	probably_damaging	1	neutral	0,44	neutral	4,51	neutral	-2,91	neutral	-0,9	medium_impact	3,17	damaging	0,37	damaging	0,12	deleterious	3,6	23,2	0,71	0,75	disease	0,71	neutral	0,3	disease	0,63	disease	0,55	1	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,18	medium_impact	1,69	0,91	0,95	27,53	7,23	P	0,63	P	0,44	polymorphism	0,94	0,06	.	.	.	.	.	.	COSM488739	.	.	G13063A	Adult-onset Encephalopathy/Ataxia	-	+	Reported	3
chrM	13063	13063	G	T	MI.20798	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	727	243	V	F	Gtc/Ttc	-9,22	0	0	probably_damaging	1	neutral	0,74	neutral	4,4	deleterious	-4,96	deleterious	-4,51	high_impact	4,82	damaging	0,33	damaging	0,1	deleterious	3,83	23,4	0,28	0,45	disease	0,86	disease	0,67	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,48	high_impact	3,2	0,79	0,85	27,53	7,23	P	0,6	P	0,95	disease_causing	0,71	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13063	13063	G	C	MI.20799	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	727	243	V	L	Gtc/Ctc	-9,22	0	0	probably_damaging	1	neutral	0,86	neutral	4,5	deleterious	-4,21	deleterious	-2,7	high_impact	5,17	damaging	0,32	damaging	0,09	deleterious	3,6	23,2	0,55	0,6	disease	0,81	neutral	0,39	disease	0,68	disease	0,61	2	deleterious	1	neutral	0,43	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,67	high_impact	3,52	0,73	0,85	27,53	7,23	P	0,62	P	0,77	polymorphism	0,82	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8623	8623	A	C	MI.208	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	97	33	T	P	Acc/Ccc	-15,14	0	0	benign	0,28	neutral	0,24	neutral	4,22	neutral	-2,04	neutral	-1,57	low_impact	1,72	neutral	0,93	neutral	0,7	neutral	1,1	11,19	0,34	0,65	neutral	0,36	disease	0,76	neutral	0,48	disease	0,54	1	neutral	0,71	deleterious	0,48	neutral	-6	deleterious	0,44	medium_impact	-0,37	medium_impact	0,01	medium_impact	0,38	0,54	0,9	19,47	19,69	N	0,36	N	0,99	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6001	6001	T	G	MI.2080	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	98	33	L	R	cTa/cGa	-1,26	0	0	possibly_damaging	0,88	deleterious	0	neutral	2,54	deleterious	-3,58	deleterious	-2,8	high_impact	4,62	damaging	0,55	neutral	0,3	deleterious	3,89	23,5	0,14	0,55	neutral	0,41	disease	0,86	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,75	low_impact	-1,57	low_impact	-1,48	high_impact	3,17	0,67	0,9	10,14	39,34	N	0,49	N	0,9	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13064	13064	T	C	MI.20800	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	728	243	V	A	gTc/gCc	5,92	1	0	probably_damaging	1	neutral	0,56	neutral	4,49	deleterious	-3,42	deleterious	-3,6	high_impact	3,69	damaging	0,28	damaging	0,14	deleterious	3,57	23,2	0,66	0,7	disease	0,77	neutral	0,31	disease	0,7	disease	0,58	2	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,29	high_impact	2,17	0,58	0,8	27,53	7,23	P	0,9	P	0,52	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13064	13064	T	A	MI.20801	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	728	243	V	D	gTc/gAc	5,92	1	0	probably_damaging	1	neutral	0,23	neutral	4,39	deleterious	-8	deleterious	-6,31	high_impact	5,17	damaging	0,45	damaging	0,1	deleterious	4,64	24,5	0,14	0,4	disease	0,97	disease	0,69	disease	0,8	disease	0,8	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,06	high_impact	3,52	0,75	0,85	27,53	7,23	P	0,68	P	0,93	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13064	13064	T	G	MI.20802	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	728	243	V	G	gTc/gGc	5,92	1	0	probably_damaging	1	neutral	0,38	neutral	4,43	deleterious	-3,67	deleterious	-6,31	high_impact	4,82	damaging	0,34	damaging	0,13	deleterious	3,78	23,4	0,27	0,45	disease	0,73	disease	0,51	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,12	high_impact	3,2	0,68	0,85	27,53	7,23	P	0,79	P	0,89	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13066	13066	T	A	MI.20803	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	730	244	S	T	Tca/Aca	-9,45	0	0	probably_damaging	1	neutral	0,43	neutral	4,47	deleterious	-3,23	deleterious	-2,7	high_impact	4,88	damaging	0,32	neutral	0,34	deleterious	3,71	23,3	0,3	0,45	disease	0,56	neutral	0,45	disease	0,7	disease	0,58	2	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,75	low_impact	-3,6	medium_impact	0,17	high_impact	3,26	0,84	0,9	29,52	7,21	P	0,73	P	0,71	polymorphism	0,97	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13066	13066	T	C	MI.20804	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	730	244	S	P	Tca/Cca	-9,45	0	0	probably_damaging	1	neutral	0,23	neutral	4,39	deleterious	-7,26	deleterious	-4,51	high_impact	5,24	damaging	0,25	neutral	0,42	deleterious	3,96	23,6	0,25	0,45	disease	0,96	disease	0,59	disease	0,82	disease	0,75	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,06	high_impact	3,58	0,7	0,85	29,52	7,21	P	0,89	P	0,98	polymorphism	0,84	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13066	13066	T	G	MI.20805	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	730	244	S	A	Tca/Gca	-9,45	0	0	probably_damaging	1	neutral	0,56	neutral	4,46	deleterious	-4,38	deleterious	-2,7	high_impact	3,95	damaging	0,33	neutral	0,46	deleterious	3,67	23,3	0,35	0,5	disease	0,76	neutral	0,34	disease	0,69	disease	0,59	2	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,75	low_impact	-3,6	medium_impact	0,29	high_impact	2,41	0,82	0,85	29,52	7,21	P	0,6	P	0,49	polymorphism	0,99	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13067	13067	C	G	MI.20806	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	731	244	S	W	tCa/tGa	7,3	1	0	probably_damaging	1	neutral	0,19	neutral	4,38	deleterious	-8,65	deleterious	-6,31	high_impact	5,24	damaging	0,31	neutral	0,41	deleterious	4,34	24	0,13	0,4	disease	0,98	disease	0,66	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,12	high_impact	3,58	0,42	0,8	29,52	7,21	P	0,77	P	0,99	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13067	13067	C	T	MI.20807	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	731	244	S	L	tCa/tTa	7,3	1	0	probably_damaging	1	neutral	0,76	neutral	4,43	deleterious	-4,84	deleterious	-5,41	high_impact	4,88	damaging	0,21	neutral	0,36	deleterious	4,65	24,5	0,25	0,45	disease	0,85	disease	0,61	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,51	high_impact	3,26	0,85	0,9	29,52	7,21	P	0,93	P	0,99	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13069	13069	G	A	MI.20808	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	733	245	A	T	Gcc/Acc	-0,5	0,23	0	probably_damaging	1	neutral	0,4	neutral	4,45	deleterious	-4,6	deleterious	-3,6	high_impact	3,65	damaging	0,42	damaging	0,11	deleterious	4,18	23,8	0,28	0,45	disease	0,63	disease	0,66	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,14	high_impact	2,13	0,68	0,85	28,69	7,21	N	0,45	N	0,94	disease_causing	1	0,27	.	.	.	.	.	.	COSM488740	.	.	.	.	.	.	.	.
chrM	13069	13069	G	T	MI.20809	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	733	245	A	S	Gcc/Tcc	-0,5	0,23	0	probably_damaging	1	neutral	0,44	neutral	4,7	deleterious	-4,15	deleterious	-2,7	low_impact	1,7	damaging	0,51	damaging	0,1	deleterious	3,66	23,2	0,3	0,45	disease	0,76	disease	0,66	disease	0,56	disease	0,56	1	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,82	low_impact	-3,6	medium_impact	0,18	medium_impact	0,35	0,75	0,85	28,69	7,21	N	0,25	N	0,98	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6003	6003	A	T	MI.2081	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	100	34	S	C	Agc/Tgc	-11,67	0	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-5,22	deleterious	-2,88	high_impact	5,05	damaging	0,46	damaging	0,02	deleterious	3,24	22,8	0,24	0,55	disease	0,88	disease	0,77	disease	0,62	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,71	0,9	2,92	6,65	P	0,56	P	0,85	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13069	13069	G	C	MI.20810	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	733	245	A	P	Gcc/Ccc	-0,5	0,23	0	probably_damaging	1	neutral	0,22	neutral	4,34	deleterious	-7,04	deleterious	-4,51	high_impact	5,08	damaging	0,43	damaging	0,1	deleterious	3,8	23,4	0,16	0,45	disease	0,94	disease	0,69	disease	0,79	disease	0,81	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,07	high_impact	3,44	0,62	0,8	28,69	7,21	P	0,72	P	0,96	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13070	13070	C	A	MI.20811	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	734	245	A	D	gCc/gAc	7,07	1	0	probably_damaging	1	neutral	0,21	neutral	4,35	deleterious	-7,81	deleterious	-5,41	high_impact	5,08	damaging	0,52	damaging	0,09	deleterious	4,58	24,4	0,11	0,4	disease	0,97	disease	0,81	disease	0,78	disease	0,81	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,09	high_impact	3,44	0,66	0,8	28,69	7,21	P	0,69	P	0,95	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13070	13070	C	T	MI.20812	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	734	245	A	V	gCc/gTc	7,07	1	0	probably_damaging	1	neutral	0,52	neutral	4,41	deleterious	-3,27	deleterious	-3,6	high_impact	4,53	damaging	0,44	damaging	0,06	deleterious	4,39	24,1	0,35	0,5	disease	0,7	disease	0,69	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,25	high_impact	2,94	0,71	0,85	28,69	7,21	P	0,67	P	0,76	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13070	13070	C	G	MI.20813	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	734	245	A	G	gCc/gGc	7,07	1	0	probably_damaging	1	neutral	0,36	neutral	4,45	deleterious	-4,64	deleterious	-3,6	high_impact	4,27	damaging	0,44	damaging	0,12	deleterious	3,93	23,5	0,21	0,45	disease	0,92	disease	0,57	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,1	high_impact	2,7	0,79	0,85	28,69	7,21	P	0,69	P	0,82	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13072	13072	C	A	MI.20814	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	736	246	L	M	Cta/Ata	-2,11	0	0	probably_damaging	1	neutral	0,26	neutral	4,37	deleterious	-3,35	neutral	-1,8	high_impact	4,21	damaging	0,45	damaging	0,14	deleterious	3,7	23,3	0,29	0,45	disease	0,84	neutral	0,49	disease	0,64	disease	0,63	3	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	-0,02	high_impact	2,64	0,7	0,85	27,2	7,27	N	0,46	N	0,89	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13072	13072	C	G	MI.20815	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	736	246	L	V	Cta/Gta	-2,11	0	0	probably_damaging	1	neutral	0,55	neutral	4,33	neutral	-2,36	deleterious	-2,7	high_impact	4,3	damaging	0,35	damaging	0,11	deleterious	3,37	22,9	0,32	0,5	disease	0,75	disease	0,55	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,28	high_impact	2,73	0,62	0,8	27,2	7,27	P	0,51	P	0,81	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13073	13073	T	C	MI.20816	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	737	246	L	P	cTa/cCa	-0,04	0	0	probably_damaging	1	neutral	0,31	neutral	4,21	deleterious	-5,71	deleterious	-6,31	high_impact	4,76	damaging	0,35	damaging	0,09	deleterious	3,83	23,4	0,17	0,45	disease	0,96	disease	0,69	disease	0,77	disease	0,8	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,04	high_impact	3,15	0,62	0,8	27,2	7,27	P	0,64	P	0,99	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13073	13073	T	G	MI.20817	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	737	246	L	R	cTa/cGa	-0,04	0	0	probably_damaging	1	neutral	0,34	neutral	4,22	deleterious	-6,26	deleterious	-5,41	high_impact	4,76	damaging	0,41	damaging	0,08	deleterious	4,14	23,8	0,13	0,4	disease	0,95	disease	0,79	disease	0,78	disease	0,83	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,07	high_impact	3,15	0,44	0,8	27,2	7,27	P	0,63	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13073	13073	T	A	MI.20818	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	737	246	L	Q	cTa/cAa	-0,04	0	0	probably_damaging	1	neutral	0,3	neutral	4,21	deleterious	-6,13	deleterious	-5,41	high_impact	5,11	damaging	0,38	damaging	0,09	deleterious	3,99	23,6	0,16	0,45	disease	0,95	disease	0,75	disease	0,67	disease	0,8	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,03	high_impact	3,47	0,55	0,8	27,2	7,27	P	0,57	P	0,98	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13075	13075	C	G	MI.20819	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	739	247	L	V	Ctc/Gtc	3,63	1	0	probably_damaging	1	neutral	0,51	neutral	4,36	deleterious	-3,72	deleterious	-2,7	medium_impact	2,02	damaging	0,52	damaging	0,09	deleterious	3,39	23	0,34	0,5	disease	0,73	neutral	0,49	disease	0,68	disease	0,59	2	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,24	medium_impact	0,64	0,72	0,85	25,04	7,23	N	0,39	N	0,81	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6003	6003	A	G	MI.2082	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	100	34	S	G	Agc/Ggc	-11,67	0	0	probably_damaging	0,98	deleterious	0	neutral	3,19	neutral	0,63	neutral	-2,3	high_impact	4,5	damaging	0,48	damaging	0,08	deleterious	3,41	23	0,32	0,55	neutral	0,49	disease	0,64	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-2,35	low_impact	-1,48	high_impact	3,06	0,68	0,9	2,92	6,65	N	0,42	N	0,7	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13075	13075	C	T	MI.20820	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	739	247	L	F	Ctc/Ttc	3,63	1	0	probably_damaging	1	neutral	0,66	neutral	4,35	deleterious	-3,64	deleterious	-3,6	high_impact	4,34	damaging	0,53	damaging	0,09	deleterious	3,94	23,6	0,37	0,5	disease	0,81	disease	0,6	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,39	high_impact	2,76	0,56	0,8	25,04	7,23	N	0,43	N	0,99	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13075	13075	C	A	MI.20821	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	739	247	L	I	Ctc/Atc	3,63	1	0	probably_damaging	1	neutral	0,41	neutral	4,63	neutral	-1,24	neutral	-1,8	medium_impact	1,98	neutral	0,61	damaging	0,19	deleterious	4,06	23,7	0,31	0,45	disease	0,6	neutral	0,26	disease	0,66	disease	0,54	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,15	medium_impact	0,61	0,68	0,85	25,04	7,23	N	0,48	N	0,85	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13076	13076	T	A	MI.20822	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	740	247	L	H	cTc/cAc	0,87	1	0	probably_damaging	1	neutral	0,5	neutral	4,2	deleterious	-7,03	deleterious	-6,31	high_impact	4,69	damaging	0,54	damaging	0,09	deleterious	4,26	23,9	0,16	0,45	disease	0,92	disease	0,72	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,23	high_impact	3,08	0,55	0,8	25,04	7,23	P	0,52	P	0,97	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13076	13076	T	G	MI.20823	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	740	247	L	R	cTc/cGc	0,87	1	0	probably_damaging	1	neutral	0,29	neutral	4,2	deleterious	-6,51	deleterious	-5,41	high_impact	4,69	damaging	0,54	damaging	0,09	deleterious	4,14	23,8	0,13	0,4	disease	0,87	disease	0,77	disease	0,78	disease	0,76	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,02	high_impact	3,08	0,46	0,8	25,04	7,23	P	0,57	P	1	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13076	13076	T	C	MI.20824	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	740	247	L	P	cTc/cCc	0,87	1	0	probably_damaging	1	neutral	0,23	neutral	4,2	deleterious	-6,96	deleterious	-6,31	high_impact	4,69	damaging	0,48	damaging	0,1	deleterious	3,91	23,5	0,14	0,4	disease	0,96	disease	0,71	disease	0,78	disease	0,82	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,06	high_impact	3,08	0,68	0,85	25,04	7,23	P	0,55	P	0,99	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13078	13078	C	T	MI.20825	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	742	248	H	Y	Cac/Tac	-20	0	0	probably_damaging	1	neutral	1	neutral	4,43	deleterious	-4,43	deleterious	-5,41	high_impact	4,51	damaging	0,43	damaging	0,09	deleterious	3,64	23,2	0,32	0,5	disease	0,71	disease	0,78	disease	0,77	disease	0,71	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,83	low_impact	-3,6	high_impact	1,89	high_impact	2,92	0,49	0,8	29,85	7,2	N	0,43	N	1	polymorphism	0,75	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13078	13078	C	A	MI.20826	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	742	248	H	N	Cac/Aac	-20	0	0	probably_damaging	1	neutral	0,31	neutral	4,42	deleterious	-5,4	deleterious	-6,31	high_impact	5,21	damaging	0,35	damaging	0,11	deleterious	3,83	23,4	0,32	0,5	disease	0,96	disease	0,71	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,04	high_impact	3,56	0,65	0,8	29,85	7,2	N	0,48	N	0,97	polymorphism	0,79	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13078	13078	C	G	MI.20827	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	742	248	H	D	Cac/Gac	-20	0	0	probably_damaging	1	neutral	0,21	neutral	4,42	deleterious	-5,59	deleterious	-8,11	high_impact	4,51	damaging	0,48	damaging	0,11	deleterious	3,8	23,4	0,22	0,45	disease	0,98	disease	0,78	disease	0,81	disease	0,77	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,09	high_impact	2,92	0,62	0,8	29,85	7,2	N	0,42	N	0,97	polymorphism	0,53	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13079	13079	A	T	MI.20828	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	743	248	H	L	cAc/cTc	7,07	1	0	probably_damaging	1	neutral	0,77	neutral	4,85	neutral	-2,83	deleterious	-9,91	high_impact	5,21	damaging	0,35	damaging	0,09	deleterious	3,78	23,4	0,27	0,45	disease	0,51	disease	0,8	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,52	high_impact	3,56	0,49	0,8	29,85	7,2	P	0,7	P	0,97	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13079	13079	A	C	MI.20829	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	743	248	H	P	cAc/cCc	7,07	1	0	probably_damaging	1	neutral	0,26	neutral	4,42	deleterious	-5,82	deleterious	-9,01	high_impact	4,86	damaging	0,41	damaging	0,13	deleterious	3,15	22,6	0,28	0,45	disease	0,98	disease	0,8	disease	0,83	disease	0,76	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,02	high_impact	3,24	0,47	0,8	29,85	7,2	P	0,74	P	0,97	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6003	6003	A	C	MI.2083	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	100	34	S	R	Agc/Cgc	-11,67	0	0	probably_damaging	1	deleterious	0,02	neutral	2,6	deleterious	-5,14	deleterious	-2,87	high_impact	4,5	damaging	0,5	damaging	0,02	deleterious	3,66	23,2	0,15	0,55	disease	0,89	disease	0,85	disease	0,75	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-3,58	medium_impact	-0,75	high_impact	3,06	0,72	0,9	2,92	6,65	N	0,4	N	0,98	polymorphism	0,99	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13079	13079	A	G	MI.20830	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	743	248	H	R	cAc/cGc	7,07	1	0	probably_damaging	1	neutral	0,35	neutral	4,43	deleterious	-4,68	deleterious	-7,21	medium_impact	3,31	damaging	0,48	damaging	0,1	deleterious	2,93	22	0,38	0,5	disease	0,97	disease	0,78	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,89	low_impact	-3,6	medium_impact	0,08	medium_impact	1,82	0,6	0,8	29,85	7,2	N	0,48	N	0,99	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13080	13080	C	G	MI.20831	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	744	248	H	Q	caC/caG	8,44	1	0	probably_damaging	1	neutral	0,3	neutral	4,43	deleterious	-4,84	deleterious	-7,21	high_impact	5,21	damaging	0,44	damaging	0,09	deleterious	3,51	23,1	0,36	0,5	disease	0,97	disease	0,74	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,03	high_impact	3,56	0,65	0,8	29,85	7,2	P	0,68	P	0,95	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13080	13080	C	A	MI.20832	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	744	248	H	Q	caC/caA	8,44	1	0	probably_damaging	1	neutral	0,3	neutral	4,43	deleterious	-4,84	deleterious	-7,21	high_impact	5,21	damaging	0,44	damaging	0,09	deleterious	3,73	23,3	0,36	0,5	disease	0,97	disease	0,74	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,03	high_impact	3,56	0,65	0,8	29,85	7,2	P	0,68	P	0,95	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13081	13081	T	G	MI.20833	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	745	249	S	A	Tca/Gca	-0,04	0,85	0	probably_damaging	1	neutral	0,51	neutral	4,88	neutral	0,84	deleterious	-2,7	medium_impact	2,11	damaging	0,52	damaging	0,22	deleterious	3,64	23,2	0,32	0,5	neutral	0,44	neutral	0,26	disease	0,67	neutral	0,43	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,7	low_impact	-3,6	medium_impact	0,24	medium_impact	0,73	0,68	0,85	29,52	7,27	N	0,36	N	0,49	disease_causing	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13081	13081	T	A	MI.20834	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	745	249	S	T	Tca/Aca	-0,04	0,85	0	probably_damaging	1	neutral	0,39	neutral	4,44	neutral	-2,44	deleterious	-2,7	high_impact	4,59	damaging	0,51	damaging	0,04	deleterious	3,87	23,5	0,23	0,45	disease	0,85	disease	0,55	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,13	high_impact	2,99	0,62	0,8	29,52	7,27	N	0,45	N	0,71	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13081	13081	T	C	MI.20835	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	745	249	S	P	Tca/Cca	-0,04	0,85	0	probably_damaging	1	neutral	0,2	neutral	4,4	deleterious	-4,87	deleterious	-4,51	high_impact	4,59	damaging	0,51	damaging	0,06	deleterious	3,97	23,6	0,21	0,45	disease	0,97	disease	0,75	disease	0,81	disease	0,78	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,1	high_impact	2,99	0,65	0,8	29,52	7,27	P	0,56	P	0,98	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13082	13082	C	G	MI.20836	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	746	249	S	W	tCa/tGa	7,3	1	0	probably_damaging	1	neutral	0,19	neutral	4,39	deleterious	-6,71	deleterious	-6,31	high_impact	4,94	damaging	0,55	damaging	0,04	deleterious	4,28	24	0,1	0,4	disease	1	disease	0,81	disease	0,75	disease	0,79	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,12	high_impact	3,31	0,37	0,8	29,52	7,27	P	0,64	P	0,99	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13082	13082	C	T	MI.20837	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	746	249	S	L	tCa/tTa	7,3	1	0	probably_damaging	1	neutral	0,66	neutral	4,47	deleterious	-3,04	deleterious	-5,41	high_impact	4,94	damaging	0,49	damaging	0,03	deleterious	4,59	24,4	0,16	0,45	disease	0,94	disease	0,75	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,39	high_impact	3,31	0,68	0,85	29,52	7,27	P	0,67	P	0,99	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13084	13084	A	C	MI.20838	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	748	250	S	R	Agc/Cgc	-8,53	0	0	probably_damaging	1	neutral	0,35	neutral	4,54	neutral	-2,99	deleterious	-4,51	high_impact	4,81	damaging	0,55	damaging	0,04	deleterious	3,81	23,4	0,21	0,45	disease	0,63	disease	0,84	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,08	high_impact	3,19	0,61	0,8	26,87	7,22	P	0,66	P	0,99	polymorphism	0,53	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13084	13084	A	G	MI.20839	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	748	250	S	G	Agc/Ggc	-8,53	0	0	probably_damaging	1	neutral	0,34	neutral	4,68	neutral	1,61	deleterious	-3,6	high_impact	4,81	damaging	0,51	damaging	0,09	deleterious	3,56	23,1	0,48	0,55	neutral	0,39	disease	0,65	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,7	low_impact	-3,6	medium_impact	0,07	high_impact	3,19	0,65	0,8	26,87	7,22	P	0,62	P	0,86	polymorphism	0,85	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6004	6004	G	C	MI.2084	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	101	34	S	T	aGc/aCc	8,69	1	0	probably_damaging	0,95	deleterious	0	neutral	2,61	deleterious	-4,06	neutral	-1,72	high_impact	4,71	damaging	0,5	damaging	0,04	deleterious	3,21	22,7	0,31	0,55	disease	0,69	disease	0,6	disease	0,64	disease	0,59	2	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,78	low_impact	-1,96	low_impact	-1,48	high_impact	3,25	0,84	0,9	2,92	6,65	P	0,68	P	0,43	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13084	13084	A	T	MI.20840	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	748	250	S	C	Agc/Tgc	-8,53	0	0	probably_damaging	1	neutral	0,18	neutral	4,52	neutral	-2,52	deleterious	-4,51	high_impact	4,81	damaging	0,51	damaging	0,02	deleterious	3,42	23	0,25	0,45	disease	0,95	disease	0,76	disease	0,65	disease	0,76	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,13	high_impact	3,19	0,55	0,8	26,87	7,22	P	0,61	P	0,99	disease_causing_automatic	0,42	0,34	rs267606896	Pathogenic|Pathogenic	Leigh_syndrome_due_to_mitochondrial_complex_I_deficiency|Juvenile_myopathy,_encephalopathy,_lactic_acidosis_AND_stroke	RCV000010343.2|RCV000010344.2	MedGen|MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	A13084T	MELAS/Leigh Disease	-	+	Reported	4
chrM	13085	13085	G	A	MI.20841	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	749	250	S	N	aGc/aAc	6,61	1	0	probably_damaging	1	neutral	0,31	neutral	4,54	deleterious	-3,1	deleterious	-2,7	high_impact	4,81	damaging	0,51	damaging	0,03	deleterious	3,58	23,2	0,44	0,55	disease	0,56	disease	0,68	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,04	high_impact	3,19	0,38	0,8	26,87	7,22	P	0,74	P	0,87	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13085	13085	G	C	MI.20842	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	749	250	S	T	aGc/aCc	6,61	1	0	probably_damaging	1	neutral	0,42	neutral	4,72	neutral	-0,97	deleterious	-2,7	high_impact	4,12	damaging	0,51	damaging	0,05	deleterious	3,36	22,9	0,36	0,5	disease	0,64	disease	0,59	disease	0,65	disease	0,64	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,16	high_impact	2,56	0,76	0,85	26,87	7,22	P	0,55	P	0,71	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13085	13085	G	T	MI.20843	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	749	250	S	I	aGc/aTc	6,61	1	0	probably_damaging	1	neutral	0,41	neutral	4,66	neutral	-0,26	deleterious	-5,41	high_impact	4,81	damaging	0,48	damaging	0,04	deleterious	4,06	23,7	0,22	0,45	disease	0,66	disease	0,88	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,15	high_impact	3,19	0,72	0,85	26,87	7,22	P	0,69	P	0,99	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13087	13087	A	G	MI.20844	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	751	251	T	A	Act/Gct	-0,73	0,04	0	probably_damaging	1	neutral	1	neutral	4,5	neutral	-2,45	deleterious	-4,51	medium_impact	3,15	damaging	0,42	damaging	0,13	deleterious	3,42	23	0,69	0,75	disease	0,72	disease	0,59	disease	0,61	disease	0,63	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,74	low_impact	-3,6	high_impact	1,89	medium_impact	1,67	0,63	0,8	29,19	7,28	N	0,41	N	0,69	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13087	13087	A	C	MI.20845	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	751	251	T	P	Act/Cct	-0,73	0,04	0	probably_damaging	1	neutral	0,28	neutral	4,38	deleterious	-3,66	deleterious	-5,41	high_impact	5,18	damaging	0,43	damaging	0,11	deleterious	3,47	23	0,21	0,45	disease	0,91	disease	0,78	disease	0,78	disease	0,75	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,01	high_impact	3,53	0,7	0,85	29,19	7,28	P	0,72	P	0,97	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13087	13087	A	T	MI.20846	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	751	251	T	S	Act/Tct	-0,73	0,04	0	probably_damaging	1	neutral	0,87	neutral	4,41	neutral	-2,95	deleterious	-3,6	high_impact	4,38	damaging	0,46	damaging	0,1	deleterious	3,28	22,8	0,35	0,5	disease	0,79	disease	0,7	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,69	high_impact	2,8	0,72	0,85	29,19	7,28	N	0,37	N	0,89	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13088	13088	C	A	MI.20847	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	752	251	T	N	aCt/aAt	6,61	1	0	probably_damaging	1	neutral	0,48	neutral	4,38	deleterious	-5,6	deleterious	-4,51	high_impact	5,18	damaging	0,37	damaging	0,09	deleterious	3,54	23,1	0,5	0,6	disease	0,95	disease	0,75	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,21	high_impact	3,53	0,83	0,9	29,19	7,28	P	0,7	P	0,93	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13088	13088	C	G	MI.20848	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	752	251	T	S	aCt/aGt	6,61	1	0	probably_damaging	1	neutral	0,87	neutral	4,41	neutral	-2,95	deleterious	-3,6	high_impact	4,38	damaging	0,46	damaging	0,1	deleterious	3,44	23	0,35	0,5	disease	0,79	disease	0,7	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,69	high_impact	2,8	0,72	0,85	29,19	7,28	P	0,53	P	0,89	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13088	13088	C	T	MI.20849	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	752	251	T	I	aCt/aTt	6,61	1	0	probably_damaging	1	neutral	0,32	neutral	4,55	neutral	-2,44	deleterious	-5,41	high_impact	4,63	damaging	0,4	damaging	0,1	deleterious	3,83	23,4	0,49	0,55	disease	0,55	disease	0,85	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,75	low_impact	-3,6	medium_impact	0,05	high_impact	3,03	0,74	0,85	29,19	7,28	P	0,7	P	0,95	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6004	6004	G	A	MI.2085	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	101	34	S	N	aGc/aAc	8,69	1	0	probably_damaging	0,95	deleterious	0	neutral	2,61	deleterious	-4,04	neutral	-1,73	high_impact	5,05	damaging	0,42	damaging	0,04	deleterious	3,49	23,1	0,52	0,6	disease	0,83	disease	0,77	disease	0,64	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,81	low_impact	-1,96	low_impact	-1,48	high_impact	3,56	0,56	0,9	2,92	6,65	P	0,73	P	0,66	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13090	13090	A	G	MI.20850	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	754	252	M	V	Ata/Gta	-8,76	0	0	probably_damaging	0,99	neutral	0,49	neutral	4,6	neutral	-2,27	deleterious	-3,6	medium_impact	3,37	damaging	0,4	damaging	0,06	deleterious	2,78	21,3	0,62	0,65	disease	0,55	disease	0,87	disease	0,69	disease	0,71	4	deleterious	0,99	neutral	0,25	deleterious	1	deleterious	0,74	low_impact	-2,64	medium_impact	0,22	medium_impact	1,88	0,65	0,8	28,86	7,2	N	0,35	N	0,95	polymorphism	0,97	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13090	13090	A	T	MI.20851	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	754	252	M	L	Ata/Tta	-8,76	0	0	probably_damaging	0,98	neutral	1	neutral	5	neutral	-1,03	deleterious	-2,7	medium_impact	2,27	damaging	0,44	damaging	0,05	deleterious	3,48	23,1	0,54	0,6	neutral	0,45	disease	0,83	disease	0,62	disease	0,56	1	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,68	low_impact	-2,35	high_impact	1,89	medium_impact	0,87	0,62	0,8	28,86	7,2	N	0,3	N	0,98	polymorphism	0,98	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13090	13090	A	C	MI.20852	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	754	252	M	L	Ata/Cta	-8,76	0	0	probably_damaging	0,98	neutral	1	neutral	5	neutral	-1,03	deleterious	-2,7	medium_impact	2,27	damaging	0,44	damaging	0,05	deleterious	3,29	22,8	0,54	0,6	neutral	0,45	disease	0,83	disease	0,62	disease	0,56	1	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,68	low_impact	-2,35	high_impact	1,89	medium_impact	0,87	0,62	0,8	28,86	7,2	N	0,29	N	0,98	polymorphism	0,98	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13091	13091	T	A	MI.20853	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	755	252	M	K	aTa/aAa	5,46	1	0	probably_damaging	1	neutral	0,25	neutral	4,52	neutral	-2,68	deleterious	-5,41	high_impact	4,65	damaging	0,45	damaging	0,04	deleterious	3,88	23,5	0,19	0,45	disease	0,92	disease	0,92	disease	0,77	disease	0,67	3	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,03	high_impact	3,04	0,48	0,8	28,86	7,2	P	0,7	P	1	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13091	13091	T	C	MI.20854	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	755	252	M	T	aTa/aCa	5,46	1	0	probably_damaging	1	neutral	0,49	neutral	4,55	deleterious	-4,18	deleterious	-5,41	high_impact	4,45	damaging	0,43	damaging	0,07	deleterious	2,91	21,9	0,47	0,55	disease	0,59	disease	0,85	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,22	high_impact	2,86	0,49	0,8	28,86	7,2	P	0,58	P	0,99	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13092	13092	A	T	MI.20855	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	756	252	M	I	atA/atT	5,69	1	0	probably_damaging	0,99	neutral	0,32	neutral	4,6	deleterious	-3,31	deleterious	-3,6	high_impact	4,3	damaging	0,41	damaging	0,07	deleterious	3,48	23,1	0,48	0,55	disease	0,77	disease	0,88	disease	0,7	disease	0,71	4	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-2,64	medium_impact	0,05	high_impact	2,73	0,73	0,85	28,86	7,2	P	0,72	P	0,94	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13092	13092	A	C	MI.20856	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	756	252	M	I	atA/atC	5,69	1	0	probably_damaging	0,99	neutral	0,32	neutral	4,6	deleterious	-3,31	deleterious	-3,6	high_impact	4,3	damaging	0,41	damaging	0,07	deleterious	3,32	22,9	0,48	0,55	disease	0,77	disease	0,88	disease	0,7	disease	0,71	4	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-2,64	medium_impact	0,05	high_impact	2,73	0,73	0,85	28,86	7,2	P	0,71	P	0,94	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13093	13093	G	A	MI.20857	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	757	253	V	I	Gtt/Att	1,1	1	0	probably_damaging	1	neutral	0,49	neutral	4,36	neutral	-1,53	neutral	-0,9	high_impact	5,25	damaging	0,43	damaging	0,11	deleterious	3,6	23,2	0,56	0,6	disease	0,68	disease	0,72	disease	0,51	disease	0,54	1	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,22	high_impact	3,59	0,85	0,9	28,19	7,17	P	0,69	P	0,44	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13093	13093	G	C	MI.20858	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	757	253	V	L	Gtt/Ctt	1,1	1	0	probably_damaging	1	neutral	1	neutral	4,5	neutral	-0,63	deleterious	-2,7	high_impact	5,25	damaging	0,34	damaging	0,1	deleterious	3,47	23	0,43	0,55	disease	0,54	disease	0,81	disease	0,55	disease	0,65	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,79	low_impact	-3,6	high_impact	1,89	high_impact	3,59	0,66	0,8	28,19	7,17	P	0,67	P	0,77	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13093	13093	G	T	MI.20859	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	757	253	V	F	Gtt/Ttt	1,1	1	0	probably_damaging	1	neutral	0,7	neutral	4,21	deleterious	-4,21	deleterious	-4,51	high_impact	5,25	damaging	0,4	damaging	0,09	deleterious	3,78	23,4	0,22	0,45	disease	0,9	disease	0,92	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,44	high_impact	3,59	0,7	0,85	28,19	7,17	P	0,64	P	0,95	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6004	6004	G	T	MI.2086	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	101	34	S	I	aGc/aTc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-5,95	deleterious	-3,45	high_impact	5,05	damaging	0,51	damaging	0,04	deleterious	3,93	23,5	0,22	0,55	disease	0,9	disease	0,88	disease	0,65	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,71	0,9	2,92	6,65	P	0,68	P	0,96	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13094	13094	T	C	MI.20860	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	758	253	V	A	gTt/gCt	8,9	1	0	probably_damaging	1	neutral	0,62	neutral	4,23	deleterious	-3,48	deleterious	-3,6	high_impact	4,7	damaging	0,22	damaging	0,14	deleterious	3,52	23,1	0,46	0,55	disease	0,81	disease	0,69	disease	0,58	disease	0,65	3	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,35	high_impact	3,09	0,52	0,8	28,19	7,17	P	0,89	P	0,52	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	T13094C	Ataxia+PEO/MELAS,LD,myoclonus,fatigue	+	+	Reported	3
chrM	13094	13094	T	A	MI.20861	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	758	253	V	D	gTt/gAt	8,9	1	0	probably_damaging	1	neutral	0,23	neutral	4,19	deleterious	-5,78	deleterious	-6,31	high_impact	5,25	damaging	0,53	damaging	0,1	deleterious	4,46	24,2	0,1	0,4	disease	0,92	disease	0,92	disease	0,71	disease	0,65	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,06	high_impact	3,59	0,58	0,8	28,19	7,17	P	0,67	P	0,93	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13094	13094	T	G	MI.20862	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	758	253	V	G	gTt/gGt	8,9	1	0	probably_damaging	1	neutral	0,5	neutral	4,2	deleterious	-5,26	deleterious	-6,31	high_impact	5,25	damaging	0,38	damaging	0,14	deleterious	3,79	23,4	0,25	0,45	disease	0,93	disease	0,86	disease	0,62	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,23	high_impact	3,59	0,48	0,8	28,19	7,17	P	0,76	P	0,89	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13096	13096	G	A	MI.20863	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	760	254	V	M	Gta/Ata	-14,95	0	0	probably_damaging	0,99	neutral	0,38	neutral	4,49	neutral	-1,68	neutral	-2,46	medium_impact	2,82	neutral	0,6	neutral	0,77	deleterious	3,63	23,2	0,58	0,65	disease	0,81	disease	0,84	disease	0,52	disease	0,67	3	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,78	low_impact	-2,64	medium_impact	0,12	medium_impact	1,37	0,84	0,9	4,81	11,14	N	0,31	N	0,7	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13096	13096	G	C	MI.20864	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	760	254	V	L	Gta/Cta	-14,95	0	0	possibly_damaging	0,76	neutral	0,74	neutral	4,59	neutral	-0,56	deleterious	-2,56	high_impact	4,06	damaging	0,55	neutral	0,47	deleterious	3,48	23,1	0,48	0,55	disease	0,57	disease	0,84	disease	0,58	disease	0,68	4	neutral	0,71	deleterious	0,49	deleterious	1	deleterious	0,78	low_impact	-1,22	medium_impact	0,48	high_impact	2,51	0,6	0,8	4,81	11,14	N	0,31	N	0,69	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13096	13096	G	T	MI.20865	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	760	254	V	L	Gta/Tta	-14,95	0	0	possibly_damaging	0,76	neutral	0,74	neutral	4,59	neutral	-0,56	deleterious	-2,56	high_impact	4,06	damaging	0,55	neutral	0,47	deleterious	3,63	23,2	0,48	0,55	disease	0,57	disease	0,84	disease	0,58	disease	0,68	4	neutral	0,71	deleterious	0,49	deleterious	1	deleterious	0,78	low_impact	-1,22	medium_impact	0,48	high_impact	2,51	0,6	0,8	4,81	11,14	N	0,31	N	0,69	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13097	13097	T	C	MI.20866	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	761	254	V	A	gTa/gCa	5	1	0	probably_damaging	0,92	neutral	0,66	neutral	4,55	neutral	0,72	deleterious	-3,53	low_impact	1,84	damaging	0,57	neutral	0,52	deleterious	3,49	23,1	0,58	0,65	disease	0,51	disease	0,73	disease	0,58	disease	0,63	3	neutral	0,91	neutral	0,37	neutral	-2	deleterious	0,75	low_impact	-1,75	medium_impact	0,39	medium_impact	0,48	0,62	0,8	4,81	11,14	N	0,43	N	0,75	disease_causing	0,97	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13097	13097	T	G	MI.20867	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	761	254	V	G	gTa/gGa	5	1	0	probably_damaging	0,99	neutral	0,4	neutral	4,47	neutral	-2,42	deleterious	-6,2	high_impact	3,51	damaging	0,55	neutral	0,54	deleterious	3,77	23,4	0,32	0,5	disease	0,86	disease	0,89	disease	0,61	disease	0,68	4	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-2,64	medium_impact	0,14	high_impact	2	0,54	0,8	4,81	11,14	N	0,45	N	0,91	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13097	13097	T	A	MI.20868	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	761	254	V	E	gTa/gAa	5	1	0	probably_damaging	0,99	neutral	0,29	neutral	4,48	neutral	-2,34	deleterious	-5,3	high_impact	3,71	damaging	0,58	neutral	0,4	deleterious	4,53	24,3	0,24	0,45	disease	0,83	disease	0,93	disease	0,72	disease	0,72	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,87	low_impact	-2,64	medium_impact	0,02	high_impact	2,19	0,56	0,8	4,81	11,14	P	0,54	P	0,99	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13099	13099	G	A	MI.20869	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	763	255	A	T	Gca/Aca	-4,4	0	0	probably_damaging	1	neutral	0,44	neutral	4,25	deleterious	-3,88	deleterious	-3,6	high_impact	4,04	damaging	0,34	damaging	0,09	deleterious	4,18	23,8	0,5	0,6	disease	0,73	disease	0,81	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,18	high_impact	2,49	0,77	0,85	28,36	7,18	N	0,48	N	0,94	disease_causing	0,62	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6006	6006	C	T	MI.2087	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	103	35	L	F	Ctc/Ttc	-1,26	0	0	benign	0,02	deleterious	0,04	neutral	2,44	neutral	-2,67	neutral	-1,58	low_impact	1,83	damaging	0,56	damaging	0,1	deleterious	3,83	23,4	0,38	0,55	disease	0,59	neutral	0,46	neutral	0,26	disease	0,61	2	neutral	0,96	deleterious	0,51	neutral	-2	neutral	0,23	medium_impact	0,83	medium_impact	-0,58	medium_impact	0,59	0,7	0,9	9,16	26,4	N	0,35	N	0,67	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13099	13099	G	T	MI.20870	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	763	255	A	S	Gca/Tca	-4,4	0	0	probably_damaging	1	neutral	0,49	neutral	4,23	deleterious	-4,48	deleterious	-2,7	medium_impact	3,36	damaging	0,46	damaging	0,11	deleterious	3,66	23,2	0,33	0,5	disease	0,79	disease	0,83	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,22	medium_impact	1,87	0,82	0,85	28,36	7,18	N	0,3	N	0,98	polymorphism	0,58	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13099	13099	G	C	MI.20871	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	763	255	A	P	Gca/Cca	-4,4	0	0	probably_damaging	1	neutral	0,22	neutral	4,19	deleterious	-6,82	deleterious	-4,51	high_impact	5,2	damaging	0,44	damaging	0,09	deleterious	3,77	23,4	0,18	0,45	disease	0,96	disease	0,87	disease	0,76	disease	0,72	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,07	high_impact	3,55	0,7	0,85	28,36	7,18	P	0,6	P	0,96	disease_causing	0,85	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13100	13100	C	T	MI.20872	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	764	255	A	V	gCa/gTa	8,9	1	0	probably_damaging	1	neutral	0,55	neutral	4,31	neutral	-2,33	deleterious	-3,6	high_impact	4,16	damaging	0,34	damaging	0,06	deleterious	4,37	24,1	0,54	0,6	disease	0,66	disease	0,88	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,28	high_impact	2,6	0,73	0,85	28,36	7,18	P	0,73	P	0,76	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13100	13100	C	G	MI.20873	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	764	255	A	G	gCa/gGa	8,9	1	0	probably_damaging	1	neutral	0,37	neutral	4,19	deleterious	-3,88	deleterious	-3,6	high_impact	4,39	damaging	0,4	damaging	0,12	deleterious	3,87	23,5	0,31	0,45	disease	0,94	disease	0,81	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,11	high_impact	2,81	0,82	0,85	28,36	7,18	P	0,69	P	0,82	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13100	13100	C	A	MI.20874	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	764	255	A	E	gCa/gAa	8,9	1	0	probably_damaging	1	neutral	0,35	neutral	4,19	deleterious	-6,72	deleterious	-4,51	high_impact	5,2	damaging	0,46	damaging	0,09	deleterious	4,45	24,2	0,15	0,4	disease	0,95	disease	0,9	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,08	high_impact	3,55	0,69	0,85	28,36	7,18	P	0,71	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13102	13102	G	C	MI.20875	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	766	256	G	R	Gga/Cga	-3,03	0	0	probably_damaging	1	neutral	0,39	neutral	4,16	deleterious	-6,82	deleterious	-7,21	high_impact	5,23	damaging	0,43	damaging	0,08	deleterious	3,91	23,5	0,16	0,45	disease	0,95	disease	0,89	disease	0,8	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,13	high_impact	3,57	0,83	0,9	28,19	7,18	P	0,58	P	1	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13102	13102	G	T	MI.20876	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	766	256	G	W	Gga/Tga	-3,03	0	0	probably_damaging	1	neutral	0,18	neutral	4,13	deleterious	-8,77	deleterious	-7,21	high_impact	5,23	damaging	0,5	damaging	0,06	deleterious	4,37	24,1	0,15	0,45	disease	0,98	disease	0,9	disease	0,73	disease	0,67	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,13	high_impact	3,57	0,46	0,8	28,19	7,18	N	0,46	N	1	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13103	13103	G	A	MI.20877	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	767	256	G	E	gGa/gAa	7,07	1	0	probably_damaging	1	neutral	0,36	neutral	4,18	deleterious	-6,88	deleterious	-7,21	high_impact	5,23	damaging	0,45	damaging	0,06	deleterious	3,84	23,4	0,17	0,45	disease	0,94	disease	0,88	disease	0,8	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,1	high_impact	3,57	0,73	0,85	28,19	7,18	P	0,66	P	1	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13103	13103	G	C	MI.20878	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	767	256	G	A	gGa/gCa	7,07	1	0	probably_damaging	1	neutral	0,59	neutral	4,27	deleterious	-3,6	deleterious	-5,41	high_impact	5,23	damaging	0,48	damaging	0,09	deleterious	3,06	22,4	0,33	0,5	disease	0,72	disease	0,72	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,32	high_impact	3,57	0,68	0,85	28,19	7,18	P	0,65	P	0,79	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13103	13103	G	T	MI.20879	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	767	256	G	V	gGa/gTa	7,07	1	0	probably_damaging	1	neutral	0,54	neutral	4,17	deleterious	-5	deleterious	-8,11	high_impact	5,23	damaging	0,39	damaging	0,05	deleterious	3,69	23,3	0,18	0,45	disease	0,84	disease	0,9	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,27	high_impact	3,57	0,52	0,8	28,19	7,18	P	0,65	P	0,98	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6006	6006	C	G	MI.2088	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	103	35	L	V	Ctc/Gtc	-1,26	0	0	benign	0,03	neutral	0,08	neutral	2,55	neutral	-1,37	neutral	-0,6	neutral_impact	0,75	neutral	0,63	damaging	0,25	deleterious	1,96	15,98	0,39	0,55	neutral	0,37	neutral	0,15	neutral	0,2	neutral	0,28	4	neutral	0,92	deleterious	0,53	neutral	-6	neutral	0,16	medium_impact	0,66	medium_impact	-0,4	medium_impact	-0,41	0,77	0,9	9,16	26,4	N	0,47	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13105	13105	A	G	MI.20880	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	769	257	I	V	Atc/Gtc	-8,76	0	0,05	benign	0,01	neutral	0,52	neutral	4,65	neutral	1,31	neutral	0,02	neutral_impact	-0,72	neutral	0,94	neutral	0,96	neutral	-0,58	0,14	0,71	0,75	neutral	0,36	neutral	0,11	neutral	0,37	neutral	0,29	4	neutral	0,47	deleterious	0,76	neutral	-6	neutral	0,1	medium_impact	1,15	medium_impact	0,25	low_impact	-1,86	0,58	0,8	5,97	12,48	N	0,32	N	0	polymorphism	1	0,03	rs2853501	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13105	13105	A	C	MI.20881	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	769	257	I	L	Atc/Ctc	-8,76	0	0,05	benign	0,08	neutral	0,68	neutral	4,82	neutral	-0,65	neutral	-1,8	medium_impact	2,56	neutral	0,68	neutral	0,41	deleterious	1,93	15,76	0,4	0,5	neutral	0,49	disease	0,65	disease	0,56	disease	0,63	3	neutral	0,23	deleterious	0,8	neutral	-3	neutral	0,23	medium_impact	0,26	medium_impact	0,41	medium_impact	1,14	0,77	0,85	5,97	12,48	N	0,25	N	0,63	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13105	13105	A	T	MI.20882	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	769	257	I	F	Atc/Ttc	-8,76	0	0,05	possibly_damaging	0,65	neutral	0,72	neutral	4,53	neutral	-1,42	deleterious	-3,6	high_impact	3,74	neutral	0,67	neutral	0,38	deleterious	3,59	23,2	0,39	0,5	disease	0,66	disease	0,8	disease	0,64	disease	0,66	3	neutral	0,57	deleterious	0,54	deleterious	1	deleterious	0,7	low_impact	-1	medium_impact	0,46	high_impact	2,21	0,8	0,85	5,97	12,48	N	0,27	N	0,89	polymorphism	0,78	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13106	13106	T	A	MI.20883	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	770	257	I	N	aTc/aAc	0,64	0,08	0	possibly_damaging	0,89	neutral	0,33	neutral	4,46	deleterious	-4,73	deleterious	-5,85	high_impact	4,08	neutral	0,67	neutral	0,38	deleterious	4,56	24,4	0,29	0,45	disease	0,84	disease	0,82	disease	0,64	disease	0,68	4	neutral	0,9	neutral	0,22	deleterious	1	deleterious	0,79	low_impact	-1,61	medium_impact	0,06	high_impact	2,52	0,72	0,85	5,97	12,48	N	0,42	N	0,92	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13106	13106	T	G	MI.20884	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	770	257	I	S	aTc/aGc	0,64	0,08	0	possibly_damaging	0,65	neutral	0,43	neutral	4,48	deleterious	-3,01	deleterious	-4,95	high_impact	3,54	neutral	0,71	neutral	0,45	deleterious	3,95	23,6	0,31	0,45	disease	0,69	disease	0,84	disease	0,65	disease	0,7	4	neutral	0,66	neutral	0,39	deleterious	1	deleterious	0,62	low_impact	-1	medium_impact	0,17	high_impact	2,03	0,64	0,8	5,97	12,48	N	0,38	N	0,87	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13106	13106	T	C	MI.20885	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	770	257	I	T	aTc/aCc	0,64	0,08	0	benign	0,25	neutral	0,44	neutral	4,52	neutral	-1,31	deleterious	-3,58	medium_impact	3,39	neutral	0,68	neutral	0,38	neutral	1,71	14,45	0,56	0,6	disease	0,66	disease	0,69	disease	0,63	disease	0,65	3	neutral	0,47	deleterious	0,6	neutral	-3	deleterious	0,52	medium_impact	-0,29	medium_impact	0,18	medium_impact	1,89	0,71	0,85	5,97	12,48	N	0,35	N	0,86	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13107	13107	C	A	MI.20886	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	771	257	I	M	atC/atA	7,3	0,95	0	possibly_damaging	0,8	neutral	0,25	neutral	4,53	neutral	-2,48	neutral	-2,24	medium_impact	3,4	neutral	0,74	neutral	0,49	deleterious	3,65	23,2	0,49	0,55	disease	0,74	disease	0,61	disease	0,62	disease	0,65	3	neutral	0,86	neutral	0,23	NA	0	deleterious	0,67	low_impact	-1,32	medium_impact	-0,03	medium_impact	1,9	0,85	0,9	5,97	12,48	P	0,55	P	0,7	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13107	13107	C	G	MI.20887	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	771	257	I	M	atC/atG	7,3	0,95	0	possibly_damaging	0,8	neutral	0,25	neutral	4,53	neutral	-2,48	neutral	-2,24	medium_impact	3,4	neutral	0,74	neutral	0,49	deleterious	3,23	22,8	0,49	0,55	disease	0,74	disease	0,61	disease	0,62	disease	0,65	3	neutral	0,86	neutral	0,23	NA	0	deleterious	0,67	low_impact	-1,32	medium_impact	-0,03	medium_impact	1,9	0,85	0,9	5,97	12,48	P	0,55	P	0,7	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13108	13108	T	G	MI.20888	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	772	258	F	V	Ttc/Gtc	-9,68	0	0	probably_damaging	0,91	neutral	0,64	neutral	4,62	neutral	-2,17	deleterious	-6,31	high_impact	3,77	damaging	0,45	neutral	0,45	deleterious	4,05	23,7	0,34	0,5	disease	0,66	disease	0,91	disease	0,72	disease	0,73	5	neutral	0,9	neutral	0,37	deleterious	2	deleterious	0,81	low_impact	-1,7	medium_impact	0,37	high_impact	2,24	0,75	0,85	6,8	8,13	N	0,4	N	0,95	polymorphism	0,61	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13108	13108	T	A	MI.20889	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	772	258	F	I	Ttc/Atc	-9,68	0	0	probably_damaging	0,94	neutral	0,64	neutral	4,65	neutral	-2,27	deleterious	-5,41	medium_impact	3,48	damaging	0,52	neutral	0,61	deleterious	4,36	24,1	0,24	0,45	neutral	0,48	disease	0,89	disease	0,66	disease	0,71	4	neutral	0,92	neutral	0,35	deleterious	1	deleterious	0,78	low_impact	-1,88	medium_impact	0,37	medium_impact	1,98	0,63	0,8	6,8	8,13	N	0,37	N	0,95	polymorphism	0,77	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6006	6006	C	A	MI.2089	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	103	35	L	I	Ctc/Atc	-1,26	0	0	benign	0,02	neutral	0,35	neutral	2,52	neutral	-1,67	neutral	-0,33	low_impact	1,4	neutral	0,7	neutral	0,95	deleterious	2,45	19,17	0,37	0,55	neutral	0,44	neutral	0,22	neutral	0,22	neutral	0,42	2	neutral	0,64	deleterious	0,67	neutral	-6	neutral	0,17	medium_impact	0,83	medium_impact	0,04	medium_impact	0,19	0,75	0,9	9,16	26,4	P	0,53	P	0,05	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13108	13108	T	C	MI.20890	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	772	258	F	L	Ttc/Ctc	-9,68	0	0	possibly_damaging	0,81	neutral	1	neutral	4,6	neutral	-1,74	deleterious	-5,41	high_impact	3,68	damaging	0,44	neutral	0,49	deleterious	4,04	23,7	0,45	0,55	neutral	0,43	disease	0,83	disease	0,68	disease	0,69	4	neutral	0,81	deleterious	0,6	deleterious	1	deleterious	0,74	low_impact	-1,34	high_impact	1,89	high_impact	2,16	0,79	0,85	6,8	8,13	N	0,45	N	0,92	polymorphism	0,75	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13109	13109	T	C	MI.20891	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	773	258	F	S	tTc/tCc	7,3	1	0	probably_damaging	0,96	neutral	0,58	neutral	4,57	deleterious	-3,42	deleterious	-7,21	high_impact	3,88	damaging	0,55	neutral	0,59	deleterious	4,2	23,9	0,26	0,45	disease	0,84	disease	0,89	disease	0,7	disease	0,67	3	neutral	0,95	neutral	0,31	deleterious	2	deleterious	0,83	low_impact	-2,06	medium_impact	0,31	high_impact	2,34	0,65	0,8	6,8	8,13	P	0,55	P	0,97	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13109	13109	T	G	MI.20892	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	773	258	F	C	tTc/tGc	7,3	1	0	probably_damaging	0,99	neutral	0,15	neutral	4,51	deleterious	-5,01	deleterious	-7,21	high_impact	4,58	damaging	0,52	neutral	0,46	deleterious	4,08	23,7	0,28	0,45	disease	0,92	disease	0,88	disease	0,73	disease	0,66	3	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,82	low_impact	-2,64	medium_impact	-0,18	high_impact	2,98	0,43	0,8	6,8	8,13	P	0,58	P	0,99	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13109	13109	T	A	MI.20893	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	773	258	F	Y	tTc/tAc	7,3	1	0	benign	0,17	neutral	0,79	neutral	4,85	neutral	1,27	deleterious	-2,7	neutral_impact	0,39	damaging	0,48	neutral	0,68	deleterious	4,19	23,8	0,25	0,45	neutral	0,43	disease	0,78	disease	0,66	neutral	0,39	2	neutral	0,11	deleterious	0,81	neutral	-6	deleterious	0,73	medium_impact	-0,09	medium_impact	0,55	medium_impact	-0,85	0,67	0,85	6,8	8,13	P	0,56	P	0,88	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13110	13110	C	A	MI.20894	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	774	258	F	L	ttC/ttA	5,69	1	0	possibly_damaging	0,81	neutral	1	neutral	4,6	neutral	-1,74	deleterious	-5,41	high_impact	3,68	damaging	0,44	neutral	0,49	deleterious	4,65	24,5	0,45	0,55	neutral	0,43	disease	0,83	disease	0,68	disease	0,69	4	neutral	0,81	deleterious	0,6	deleterious	1	deleterious	0,74	low_impact	-1,34	high_impact	1,89	high_impact	2,16	0,79	0,85	6,8	8,13	P	0,68	P	0,92	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13110	13110	C	G	MI.20895	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	774	258	F	L	ttC/ttG	5,69	1	0	possibly_damaging	0,81	neutral	1	neutral	4,6	neutral	-1,74	deleterious	-5,41	high_impact	3,68	damaging	0,44	neutral	0,49	deleterious	4,35	24,1	0,45	0,55	neutral	0,43	disease	0,83	disease	0,68	disease	0,69	4	neutral	0,81	deleterious	0,6	deleterious	1	deleterious	0,74	low_impact	-1,34	high_impact	1,89	high_impact	2,16	0,79	0,85	6,8	8,13	P	0,68	P	0,92	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13111	13111	T	A	MI.20896	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	775	259	L	M	Tta/Ata	-0,73	0	0	probably_damaging	1	neutral	0,33	neutral	4,3	neutral	-2,67	neutral	-1,73	medium_impact	2,77	damaging	0,56	damaging	0,13	deleterious	3,49	23,1	0,3	0,45	disease	0,76	disease	0,57	disease	0,53	neutral	0,35	3	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,06	medium_impact	1,33	0,68	0,85	6,14	10,21	N	0,29	N	0,89	disease_causing	0,94	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13111	13111	T	G	MI.20897	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	775	259	L	V	Tta/Gta	-0,73	0	0	probably_damaging	1	neutral	0,78	neutral	4,37	neutral	-2,28	deleterious	-2,56	medium_impact	2,83	damaging	0,48	damaging	0,09	deleterious	3,35	22,9	0,27	0,45	disease	0,72	disease	0,76	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,54	medium_impact	1,38	0,52	0,8	6,14	10,21	N	0,23	N	0,81	disease_causing	0,95	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13112	13112	T	C	MI.20898	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	776	259	L	S	tTa/tCa	-0,27	0	0	probably_damaging	1	neutral	0,59	neutral	4,28	deleterious	-4,1	deleterious	-5,13	high_impact	5,09	damaging	0,56	damaging	0,1	deleterious	3,72	23,3	0,17	0,45	disease	0,79	disease	0,85	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,32	high_impact	3,45	0,62	0,8	6,14	10,21	P	0,6	P	0,97	polymorphism	0,94	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13112	13112	T	G	MI.20899	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	776	259	L	W	tTa/tGa	-0,27	0	0	probably_damaging	1	neutral	0,21	neutral	4,24	deleterious	-6,98	deleterious	-5,23	high_impact	5,09	damaging	0,6	damaging	0,09	deleterious	3,75	23,3	0,11	0,4	disease	0,86	disease	0,83	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,09	high_impact	3,45	0,46	0,8	6,14	10,21	P	0,61	P	0,98	polymorphism	0,9	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8624	8624	C	A	MI.209	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	98	33	T	N	aCc/aAc	-2,65	0	0	benign	0,28	neutral	0,41	neutral	4,28	neutral	-0,37	deleterious	-2,61	low_impact	0,84	neutral	0,9	neutral	0,84	deleterious	0,55	7,82	0,62	0,7	neutral	0,4	disease	0,53	neutral	0,47	neutral	0,47	1	neutral	0,51	deleterious	0,57	neutral	-6	neutral	0,34	medium_impact	-0,37	medium_impact	0,2	medium_impact	-0,38	0,66	0,9	19,47	19,69	N	0,32	N	0,39	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6007	6007	T	A	MI.2090	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	104	35	L	H	cTc/cAc	-0,11	0	0	possibly_damaging	0,88	deleterious	0	neutral	2,38	deleterious	-4,58	deleterious	-3,09	high_impact	3,69	damaging	0,59	damaging	0,11	deleterious	3,99	23,6	0,17	0,55	disease	0,83	disease	0,65	disease	0,57	disease	0,72	4	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,78	low_impact	-1,57	low_impact	-1,48	high_impact	2,31	0,68	0,9	9,16	26,4	N	0,32	N	0,66	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13113	13113	A	C	MI.20900	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	777	259	L	F	ttA/ttC	5,69	0,86	0	probably_damaging	1	neutral	0,92	neutral	4,27	deleterious	-3,57	deleterious	-3,5	medium_impact	3,27	damaging	0,56	damaging	0,16	deleterious	3,42	23	0,27	0,45	disease	0,84	disease	0,79	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,46	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,82	medium_impact	1,78	0,54	0,8	6,14	10,21	N	0,4	N	0,99	polymorphism	0,96	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13113	13113	A	T	MI.20901	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	777	259	L	F	ttA/ttT	5,69	0,86	0	probably_damaging	1	neutral	0,92	neutral	4,27	deleterious	-3,57	deleterious	-3,5	medium_impact	3,27	damaging	0,56	damaging	0,16	deleterious	3,55	23,1	0,27	0,45	disease	0,84	disease	0,79	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,46	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,82	medium_impact	1,78	0,54	0,8	6,14	10,21	N	0,4	N	0,99	polymorphism	0,96	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13114	13114	C	T	MI.20902	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	778	260	L	F	Ctc/Ttc	-3,94	0	0	probably_damaging	0,94	neutral	0,64	neutral	3,98	deleterious	-3,04	deleterious	-3,4	high_impact	3,64	damaging	0,52	neutral	0,39	deleterious	3,94	23,5	0,33	0,5	disease	0,67	disease	0,83	disease	0,66	disease	0,7	4	neutral	0,94	neutral	0,35	deleterious	2	deleterious	0,84	low_impact	-1,88	medium_impact	0,37	high_impact	2,12	0,71	0,85	11,44	15,34	N	0,3	N	0,85	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13114	13114	C	A	MI.20903	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	778	260	L	I	Ctc/Atc	-3,94	0	0	benign	0,18	neutral	0,46	neutral	4,09	neutral	-2,04	neutral	-1,6	medium_impact	1,95	neutral	0,63	neutral	0,61	deleterious	4,02	23,6	0,31	0,45	disease	0,53	disease	0,73	disease	0,56	neutral	0,44	1	neutral	0,45	deleterious	0,64	neutral	-3	deleterious	0,78	medium_impact	-0,12	medium_impact	0,19	medium_impact	0,58	0,77	0,85	11,44	15,34	N	0,26	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13114	13114	C	G	MI.20904	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	778	260	L	V	Ctc/Gtc	-3,94	0	0	possibly_damaging	0,61	neutral	0,62	neutral	4,01	neutral	-2,71	neutral	-2,43	medium_impact	2,37	damaging	0,52	neutral	0,39	deleterious	3,41	23	0,32	0,5	neutral	0,5	disease	0,69	disease	0,65	neutral	0,45	1	neutral	0,55	deleterious	0,51	NA	0	deleterious	0,77	medium_impact	-0,93	medium_impact	0,35	medium_impact	0,96	0,79	0,85	11,44	15,34	N	0,26	N	0,61	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13115	13115	T	A	MI.20905	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	779	260	L	H	cTc/cAc	-0,04	0	0	probably_damaging	0,99	neutral	0,41	neutral	3,87	deleterious	-7,14	deleterious	-6,03	high_impact	4,84	damaging	0,52	neutral	0,32	deleterious	4,22	23,9	0,15	0,45	disease	0,95	disease	0,9	disease	0,74	disease	0,73	5	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,88	low_impact	-2,64	medium_impact	0,15	high_impact	3,22	0,51	0,8	11,44	15,34	P	0,61	P	0,85	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13115	13115	T	G	MI.20906	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	779	260	L	R	cTc/cGc	-0,04	0	0	probably_damaging	0,98	neutral	0,3	neutral	3,87	deleterious	-6,53	deleterious	-5,16	high_impact	4,84	damaging	0,54	neutral	0,3	deleterious	4,14	23,8	0,14	0,4	disease	0,93	disease	0,94	disease	0,75	disease	0,72	4	deleterious	0,98	neutral	0,16	deleterious	2	deleterious	0,93	low_impact	-2,35	medium_impact	0,03	high_impact	3,22	0,42	0,8	11,44	15,34	P	0,64	P	0,97	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13115	13115	T	C	MI.20907	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	779	260	L	P	cTc/cCc	-0,04	0	0	probably_damaging	0,98	neutral	0,18	neutral	3,87	deleterious	-7,01	deleterious	-6,03	high_impact	4,84	damaging	0,49	neutral	0,34	deleterious	3,93	23,5	0,14	0,4	disease	0,78	disease	0,9	disease	0,76	disease	0,75	5	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-2,35	medium_impact	-0,13	high_impact	3,22	0,6	0,8	11,44	15,34	P	0,61	P	0,91	polymorphism	0,53	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13117	13117	A	C	MI.20908	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	781	261	I	L	Atc/Ctc	-10,14	0	0	probably_damaging	1	neutral	0,85	neutral	4,73	neutral	0,23	neutral	-1,79	low_impact	1,55	neutral	0,67	neutral	0,59	deleterious	3,76	23,3	0,37	0,5	neutral	0,35	disease	0,7	neutral	0,5	neutral	0,3	4	deleterious	1	neutral	0,43	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	0,65	medium_impact	0,21	0,74	0,85	3,81	8,06	N	0,26	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13117	13117	A	T	MI.20909	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	781	261	I	F	Atc/Ttc	-10,14	0	0	probably_damaging	1	neutral	0,75	neutral	4,58	neutral	-2,32	deleterious	-3,58	medium_impact	2,67	neutral	0,62	neutral	0,36	deleterious	3,76	23,3	0,31	0,45	disease	0,76	disease	0,85	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,5	medium_impact	1,24	0,83	0,85	3,81	8,06	N	0,22	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6007	6007	T	C	MI.2091	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	104	35	L	P	cTc/cCc	-0,11	0	0	probably_damaging	0,94	deleterious	0	neutral	2,38	deleterious	-5,12	deleterious	-3,02	high_impact	4,04	damaging	0,53	damaging	0,11	deleterious	3,75	23,3	0,15	0,55	disease	0,83	disease	0,84	disease	0,62	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,87	low_impact	-1,88	low_impact	-1,48	high_impact	2,63	0,67	0,9	9,16	26,4	N	0,31	N	0,8	polymorphism	0,91	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13117	13117	A	G	MI.20910	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	781	261	I	V	Atc/Gtc	-10,14	0	0	probably_damaging	1	neutral	0,63	neutral	4,7	neutral	-0,7	neutral	-0,64	low_impact	1,55	neutral	0,8	neutral	0,89	deleterious	1,83	15,16	0,56	0,6	disease	0,56	neutral	0,38	neutral	0,42	disease	0,58	2	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,66	low_impact	-3,6	medium_impact	0,36	medium_impact	0,21	0,61	0,8	3,81	8,06	N	0,3	N	0,35	polymorphism	1	0,02	rs878966690	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13118	13118	T	C	MI.20911	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	782	261	I	T	aTc/aCc	1,56	0,81	0	probably_damaging	1	neutral	0,63	neutral	4,6	neutral	-2,45	deleterious	-4,19	medium_impact	3,27	neutral	0,65	neutral	0,61	deleterious	3,41	23	0,4	0,5	disease	0,61	disease	0,77	disease	0,57	disease	0,56	1	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,36	medium_impact	1,78	0,69	0,85	3,81	8,06	N	0,28	N	0,95	polymorphism	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13118	13118	T	A	MI.20912	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	782	261	I	N	aTc/aAc	1,56	0,81	0	probably_damaging	1	neutral	0,52	neutral	4,57	deleterious	-4,04	deleterious	-6,13	high_impact	4,17	damaging	0,58	neutral	0,4	deleterious	4,43	24,2	0,22	0,45	disease	0,9	disease	0,87	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,25	high_impact	2,61	0,68	0,85	3,81	8,06	N	0,38	N	0,97	polymorphism	0,95	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13118	13118	T	G	MI.20913	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	782	261	I	S	aTc/aGc	1,56	0,81	0	probably_damaging	1	neutral	0,75	neutral	4,57	neutral	-2,97	deleterious	-5,23	high_impact	3,62	neutral	0,63	neutral	0,44	deleterious	4,27	24	0,27	0,45	disease	0,83	disease	0,89	disease	0,62	disease	0,68	4	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,5	high_impact	2,1	0,63	0,8	3,81	8,06	N	0,3	N	0,96	polymorphism	0,94	0,1	.	.	.	.	.	.	COSM1472301	.	.	.	.	.	.	.	.
chrM	13119	13119	C	G	MI.20914	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	783	261	I	M	atC/atG	7,3	0,98	0	probably_damaging	1	neutral	0,29	neutral	4,64	neutral	-2,05	deleterious	-2,56	medium_impact	2,4	neutral	0,65	neutral	0,47	deleterious	3,35	22,9	0,37	0,5	disease	0,72	disease	0,71	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,02	medium_impact	0,99	0,8	0,85	3,81	8,06	P	0,52	P	0,72	disease_causing	0,71	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13119	13119	C	A	MI.20915	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	783	261	I	M	atC/atA	7,3	0,98	0	probably_damaging	1	neutral	0,29	neutral	4,64	neutral	-2,05	deleterious	-2,56	medium_impact	2,4	neutral	0,65	neutral	0,47	deleterious	3,76	23,3	0,37	0,5	disease	0,72	disease	0,71	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,02	medium_impact	0,99	0,8	0,85	3,81	8,06	P	0,52	P	0,72	disease_causing	0,71	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13120	13120	C	A	MI.20916	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	784	262	R	S	Cgc/Agc	-2,57	0	0	probably_damaging	1	neutral	0,88	neutral	4,28	deleterious	-5,04	deleterious	-5,39	high_impact	4,44	damaging	0,6	damaging	0,07	deleterious	4,51	24,3	0,22	0,45	disease	0,82	disease	0,88	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,71	high_impact	2,85	0,39	0,8	29,19	7,18	N	0,44	N	0,82	disease_causing	0,99	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13120	13120	C	G	MI.20917	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	784	262	R	G	Cgc/Ggc	-2,57	0	0	probably_damaging	1	neutral	0,61	neutral	4,19	deleterious	-6,47	deleterious	-6,3	high_impact	4,44	damaging	0,49	damaging	0,08	deleterious	4,15	23,8	0,24	0,45	disease	0,94	disease	0,83	disease	0,8	disease	0,75	5	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,34	high_impact	2,85	0,28	0,8	29,19	7,18	N	0,47	N	0,97	disease_causing	0,99	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13120	13120	C	T	MI.20918	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	784	262	R	C	Cgc/Tgc	-2,57	0	0	probably_damaging	1	neutral	0,2	neutral	4,16	deleterious	-8,04	deleterious	-7,2	high_impact	4,79	damaging	0,48	damaging	0,05	deleterious	4,94	25	0,25	0,45	disease	0,97	disease	0,89	disease	0,82	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,1	high_impact	3,17	0,62	0,8	29,19	7,18	P	0,52	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13121	13121	G	T	MI.20919	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	785	262	R	L	cGc/cTc	3,4	0,99	0	probably_damaging	1	neutral	0,83	neutral	4,2	deleterious	-4,56	deleterious	-6,3	high_impact	4,04	damaging	0,5	damaging	0,04	deleterious	4,3	24	0,22	0,45	disease	0,84	disease	0,93	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,61	high_impact	2,49	0,37	0,8	29,19	7,18	P	0,54	P	1	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6007	6007	T	G	MI.2092	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	104	35	L	R	cTc/cGc	-0,11	0	0	possibly_damaging	0,84	deleterious	0	neutral	2,38	deleterious	-4,52	deleterious	-2,71	high_impact	3,69	damaging	0,55	damaging	0,09	deleterious	4,05	23,7	0,12	0,55	disease	0,77	disease	0,79	disease	0,62	disease	0,76	5	deleterious	1	neutral	0,08	deleterious	5	deleterious	0,81	low_impact	-1,43	low_impact	-1,48	high_impact	2,31	0,69	0,9	9,16	26,4	N	0,3	N	0,9	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13121	13121	G	A	MI.20920	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	785	262	R	H	cGc/cAc	3,4	0,99	0	probably_damaging	1	neutral	0,57	neutral	4,21	deleterious	-6,9	deleterious	-4,5	high_impact	4,24	damaging	0,54	damaging	0,04	deleterious	4,38	24,1	0,31	0,45	disease	0,95	disease	0,87	disease	0,81	disease	0,71	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,3	high_impact	2,67	0,65	0,8	29,19	7,18	P	0,56	P	1	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13121	13121	G	C	MI.20921	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	785	262	R	P	cGc/cCc	3,4	0,99	0	probably_damaging	1	neutral	0,39	neutral	4,18	deleterious	-6,85	deleterious	-6,3	high_impact	5,13	damaging	0,54	damaging	0,06	deleterious	4,24	23,9	0,21	0,45	disease	0,96	disease	0,9	disease	0,87	disease	0,72	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,13	high_impact	3,48	0,25	0,8	29,19	7,18	P	0,64	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13123	13123	T	A	MI.20922	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	787	263	F	I	Ttc/Atc	-14,04	0	0	possibly_damaging	0,74	neutral	0,5	neutral	4,63	neutral	-1,29	deleterious	-5,41	low_impact	0,81	neutral	0,77	neutral	0,7	deleterious	2,72	20,9	0,23	0,45	disease	0,54	disease	0,56	neutral	0,33	neutral	0,37	3	neutral	0,72	neutral	0,38	neutral	-3	neutral	0,42	low_impact	-1,18	medium_impact	0,23	medium_impact	-0,46	0,75	0,85	9,78	7,14	N	0,28	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13123	13123	T	G	MI.20923	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	787	263	F	V	Ttc/Gtc	-14,04	0	0	possibly_damaging	0,74	neutral	0,53	neutral	4,7	neutral	-1,41	deleterious	-6,31	low_impact	1,24	neutral	0,82	neutral	0,68	deleterious	2,45	19,11	0,25	0,45	disease	0,54	disease	0,67	neutral	0,4	neutral	0,38	3	neutral	0,71	neutral	0,4	neutral	-3	neutral	0,42	low_impact	-1,18	medium_impact	0,26	medium_impact	-0,07	0,74	0,85	9,78	7,14	N	0,26	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13123	13123	T	C	MI.20924	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	787	263	F	L	Ttc/Ctc	-14,04	0	0	benign	0,08	neutral	0,76	neutral	4,88	neutral	-0,4	deleterious	-5,41	neutral_impact	-0,04	neutral	0,74	neutral	0,75	deleterious	0,16	4,29	0,48	0,55	neutral	0,4	neutral	0,27	neutral	0,28	neutral	0,46	1	neutral	0,14	deleterious	0,84	neutral	-6	neutral	0,14	medium_impact	0,26	medium_impact	0,51	low_impact	-1,24	0,82	0,85	9,78	7,14	N	0,32	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13124	13124	T	C	MI.20925	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	788	263	F	S	tTc/tCc	0,87	0,06	0	probably_damaging	0,96	neutral	0,43	neutral	4,53	neutral	-2,74	deleterious	-7,21	low_impact	1,86	neutral	0,84	neutral	0,68	deleterious	4,08	23,7	0,18	0,45	disease	0,75	disease	0,6	disease	0,65	disease	0,56	1	neutral	0,95	neutral	0,24	neutral	-2	deleterious	0,69	low_impact	-2,06	medium_impact	0,17	medium_impact	0,5	0,53	0,8	9,78	7,14	N	0,32	N	0,97	polymorphism	1	0,08	.	.	.	.	.	glioblastoma	COSM1155531	.	.	.	.	.	.	.	.
chrM	13124	13124	T	A	MI.20926	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	788	263	F	Y	tTc/tAc	0,87	0,06	0	possibly_damaging	0,89	neutral	1	neutral	4,51	neutral	-2,6	deleterious	-2,7	low_impact	1,86	neutral	0,82	neutral	0,47	deleterious	3,96	23,6	0,24	0,45	disease	0,82	disease	0,6	disease	0,63	disease	0,69	4	neutral	0,89	deleterious	0,56	neutral	-3	deleterious	0,66	low_impact	-1,61	high_impact	1,89	medium_impact	0,5	0,73	0,85	9,78	7,14	N	0,2	N	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13124	13124	T	G	MI.20927	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	788	263	F	C	tTc/tGc	0,87	0,06	0	probably_damaging	0,98	neutral	0,19	neutral	4,51	deleterious	-3,46	deleterious	-7,21	low_impact	1,64	neutral	0,76	neutral	0,47	deleterious	4,05	23,7	0,23	0,45	disease	0,87	disease	0,73	disease	0,66	disease	0,69	4	deleterious	0,99	neutral	0,11	neutral	-2	deleterious	0,77	low_impact	-2,35	medium_impact	-0,12	medium_impact	0,3	0,42	0,8	9,78	7,14	N	0,31	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13125	13125	C	A	MI.20928	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	789	263	F	L	ttC/ttA	2,71	0,12	0	benign	0,08	neutral	0,76	neutral	4,88	neutral	-0,4	deleterious	-5,41	neutral_impact	-0,04	neutral	0,74	neutral	0,75	deleterious	0,73	9,02	0,48	0,55	neutral	0,4	neutral	0,27	neutral	0,28	neutral	0,46	1	neutral	0,14	deleterious	0,84	neutral	-6	neutral	0,14	medium_impact	0,26	medium_impact	0,51	low_impact	-1,24	0,82	0,85	9,78	7,14	N	0,3	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13125	13125	C	G	MI.20929	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	789	263	F	L	ttC/ttG	2,71	0,12	0	benign	0,08	neutral	0,76	neutral	4,88	neutral	-0,4	deleterious	-5,41	neutral_impact	-0,04	neutral	0,74	neutral	0,75	deleterious	0,45	7,01	0,48	0,55	neutral	0,4	neutral	0,27	neutral	0,28	neutral	0,46	1	neutral	0,14	deleterious	0,84	neutral	-6	neutral	0,14	medium_impact	0,26	medium_impact	0,51	low_impact	-1,24	0,82	0,85	9,78	7,14	N	0,31	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6009	6009	C	T	MI.2093	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	106	36	L	F	Ctt/Ttt	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-3,72	neutral	-2,06	medium_impact	2,67	damaging	0,51	damaging	0,06	deleterious	3,75	23,3	0,32	0,55	neutral	0,42	disease	0,63	neutral	0,44	disease	0,51	0	deleterious	1	neutral	0	deleterious	5	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	medium_impact	1,37	0,71	0,9	2,34	7,4	N	0,3	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13126	13126	C	G	MI.20930	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	790	264	H	D	Cac/Gac	-4,63	0	0	possibly_damaging	0,57	neutral	0,41	neutral	4,61	neutral	-1,55	deleterious	-6,08	medium_impact	2,52	neutral	0,72	neutral	0,39	deleterious	2,23	17,69	0,33	0,5	disease	0,89	disease	0,84	disease	0,78	disease	0,74	5	neutral	0,61	neutral	0,42	NA	0	deleterious	0,63	medium_impact	-0,86	medium_impact	0,15	medium_impact	1,1	0,64	0,8	2,32	8,94	N	0,28	N	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13126	13126	C	A	MI.20931	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	790	264	H	N	Cac/Aac	-4,63	0	0	possibly_damaging	0,44	neutral	0,46	neutral	4,73	neutral	1,53	deleterious	-4,74	low_impact	0,87	neutral	0,8	neutral	0,81	neutral	1,01	10,72	0,65	0,7	neutral	0,49	disease	0,74	disease	0,51	neutral	0,21	6	neutral	0,5	deleterious	0,51	neutral	-3	neutral	0,39	medium_impact	-0,65	medium_impact	0,19	medium_impact	-0,41	0,68	0,85	2,32	8,94	N	0,26	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13126	13126	C	T	MI.20932	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	790	264	H	Y	Cac/Tac	-4,63	0	0	benign	0,02	neutral	1	neutral	4,68	neutral	0,82	neutral	-0,64	neutral_impact	0,72	neutral	0,93	neutral	0,96	deleterious	0,12	3,79	0,71	0,75	neutral	0,5	disease	0,71	neutral	0,46	neutral	0,23	5	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,25	medium_impact	0,86	high_impact	1,89	medium_impact	-0,55	0,45	0,8	2,32	8,94	N	0,2	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13127	13127	A	C	MI.20933	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	791	264	H	P	cAc/cCc	-1,19	0	0	possibly_damaging	0,8	neutral	0,3	neutral	4,61	neutral	-1,5	deleterious	-6,57	high_impact	3,77	neutral	0,66	neutral	0,32	deleterious	3,44	23	0,32	0,5	disease	0,88	disease	0,93	disease	0,8	disease	0,77	5	neutral	0,84	neutral	0,25	deleterious	1	deleterious	0,81	low_impact	-1,32	medium_impact	0,03	high_impact	2,24	0,46	0,8	2,32	8,94	N	0,41	N	0,92	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13127	13127	A	T	MI.20934	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	791	264	H	L	cAc/cTc	-1,19	0	0	benign	0,36	neutral	0,81	neutral	4,79	neutral	2,1	deleterious	-6,2	medium_impact	2,27	neutral	0,78	neutral	0,46	deleterious	2,52	19,59	0,46	0,55	neutral	0,37	disease	0,88	disease	0,7	disease	0,73	5	neutral	0,24	deleterious	0,73	neutral	-3	neutral	0,34	medium_impact	-0,51	medium_impact	0,58	medium_impact	0,87	0,34	0,8	2,32	8,94	N	0,27	N	0,84	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13127	13127	A	G	MI.20935	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	791	264	H	R	cAc/cGc	-1,19	0	0	benign	0,03	neutral	0,51	neutral	4,63	neutral	-0,74	deleterious	-5,25	medium_impact	2,96	neutral	0,77	neutral	0,37	neutral	1,52	13,43	0,59	0,65	disease	0,83	disease	0,85	disease	0,73	disease	0,73	5	neutral	0,46	deleterious	0,74	neutral	-3	neutral	0,34	medium_impact	0,69	medium_impact	0,24	medium_impact	1,5	0,48	0,8	2,32	8,94	N	0,24	N	0,72	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13128	13128	C	G	MI.20936	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	792	264	H	Q	caC/caG	1,79	0	0	benign	0,04	neutral	0,48	neutral	4,62	neutral	-0,81	deleterious	-4,81	medium_impact	2,62	neutral	0,81	neutral	0,81	deleterious	1,83	15,18	0,67	0,7	disease	0,71	disease	0,68	neutral	0,49	neutral	0,28	4	neutral	0,48	deleterious	0,72	neutral	-3	deleterious	0,48	medium_impact	0,57	medium_impact	0,21	medium_impact	1,19	0,65	0,8	2,32	8,94	N	0,34	N	0,63	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13128	13128	C	A	MI.20937	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	792	264	H	Q	caC/caA	1,79	0	0	benign	0,04	neutral	0,48	neutral	4,62	neutral	-0,81	deleterious	-4,81	medium_impact	2,62	neutral	0,81	neutral	0,81	deleterious	2,11	16,92	0,67	0,7	disease	0,71	disease	0,68	neutral	0,49	neutral	0,28	4	neutral	0,48	deleterious	0,72	neutral	-3	deleterious	0,48	medium_impact	0,57	medium_impact	0,21	medium_impact	1,19	0,65	0,8	2,32	8,94	N	0,33	N	0,63	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13129	13129	C	A	MI.20938	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	793	265	P	T	Ccc/Acc	-0,73	0	0	probably_damaging	0,97	neutral	0,68	neutral	4,58	deleterious	-3,2	deleterious	-6,72	high_impact	3,59	damaging	0,57	neutral	0,4	deleterious	3,67	23,2	0,4	0,5	disease	0,81	disease	0,83	disease	0,59	disease	0,67	3	neutral	0,96	neutral	0,36	deleterious	2	deleterious	0,76	low_impact	-2,18	medium_impact	0,41	high_impact	2,08	0,75	0,85	8,62	7,2	N	0,26	N	0,91	disease_causing	0,79	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13129	13129	C	G	MI.20939	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	793	265	P	A	Ccc/Gcc	-0,73	0	0	probably_damaging	0,94	neutral	0,9	neutral	4,6	neutral	-2,84	deleterious	-6,72	medium_impact	2,79	damaging	0,55	neutral	0,47	deleterious	2,72	20,9	0,41	0,5	disease	0,77	disease	0,72	disease	0,7	disease	0,69	4	neutral	0,93	deleterious	0,48	deleterious	1	deleterious	0,66	low_impact	-1,88	medium_impact	0,76	medium_impact	1,35	0,79	0,85	8,62	7,2	N	0,21	N	0,73	disease_causing	0,71	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6009	6009	C	G	MI.2094	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	106	36	L	V	Ctt/Gtt	-20	0	0	probably_damaging	0,99	neutral	0,09	neutral	2,54	neutral	-2,52	neutral	-1,16	medium_impact	2,5	damaging	0,57	damaging	0,09	neutral	1,44	13,01	0,3	0,55	neutral	0,35	neutral	0,5	neutral	0,31	neutral	0,46	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,71	low_impact	-2,64	medium_impact	-0,37	medium_impact	1,21	0,72	0,9	2,34	7,4	N	0,3	N	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13129	13129	C	T	MI.20940	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	793	265	P	S	Ccc/Tcc	-0,73	0	0	probably_damaging	0,96	neutral	0,84	neutral	4,61	deleterious	-3,47	deleterious	-6,62	medium_impact	3,1	damaging	0,6	neutral	0,47	deleterious	3,56	23,1	0,5	0,6	disease	0,77	disease	0,81	disease	0,58	neutral	0,42	2	neutral	0,95	neutral	0,44	deleterious	1	deleterious	0,71	low_impact	-2,06	medium_impact	0,63	medium_impact	1,63	0,39	0,8	8,62	7,2	N	0,24	N	0,78	disease_causing	0,8	0,11	.	.	.	.	.	.	COSM1138246	.	.	.	.	.	.	.	.
chrM	13130	13130	C	G	MI.20941	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	794	265	P	R	cCc/cGc	4,31	0,98	0	probably_damaging	0,96	neutral	0,61	neutral	4,57	deleterious	-4,98	deleterious	-7,54	high_impact	4,45	damaging	0,55	neutral	0,38	deleterious	3,47	23	0,3	0,45	disease	0,92	disease	0,91	disease	0,81	disease	0,73	5	neutral	0,95	neutral	0,33	deleterious	2	deleterious	0,81	low_impact	-2,06	medium_impact	0,34	high_impact	2,86	0,62	0,8	8,62	7,2	P	0,59	P	0,64	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13130	13130	C	T	MI.20942	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	794	265	P	L	cCc/cTc	4,31	0,98	0	probably_damaging	0,97	neutral	0,73	neutral	4,66	neutral	-2,4	deleterious	-8,49	medium_impact	2,88	damaging	0,52	neutral	0,43	deleterious	4,29	24	0,53	0,6	neutral	0,45	disease	0,89	disease	0,66	disease	0,71	4	neutral	0,96	neutral	0,38	deleterious	1	deleterious	0,73	low_impact	-2,18	medium_impact	0,47	medium_impact	1,43	0,78	0,85	8,62	7,2	N	0,45	N	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13130	13130	C	A	MI.20943	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	794	265	P	H	cCc/cAc	4,31	0,98	0	benign	0,4	neutral	0,41	neutral	4,54	deleterious	-5,89	deleterious	-7,27	high_impact	3,59	damaging	0,55	neutral	0,55	deleterious	2,09	16,76	0,38	0,5	disease	0,94	disease	0,88	disease	0,72	disease	0,68	4	neutral	0,53	deleterious	0,51	neutral	-2	neutral	0,36	medium_impact	-0,58	medium_impact	0,15	high_impact	2,08	0,66	0,8	8,62	7,2	N	0,48	N	0,72	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13132	13132	C	A	MI.20944	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	796	266	L	M	Cta/Ata	-20	0	0,01	possibly_damaging	0,49	neutral	0,28	neutral	4,28	deleterious	-3,18	neutral	-1,37	low_impact	1,5	neutral	0,84	neutral	0,89	deleterious	2,33	18,39	0,37	0,5	disease	0,77	neutral	0,22	neutral	0,22	disease	0,53	1	neutral	0,69	neutral	0,4	neutral	-3	deleterious	0,73	medium_impact	-0,73	medium_impact	0,01	medium_impact	0,17	0,72	0,85	14,76	12,06	N	0,43	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13132	13132	C	G	MI.20945	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	796	266	L	V	Cta/Gta	-20	0	0,01	possibly_damaging	0,81	neutral	0,58	neutral	4,36	neutral	-2,14	neutral	-2,13	low_impact	1,42	neutral	0,8	neutral	0,62	deleterious	3,37	22,9	0,41	0,5	disease	0,68	disease	0,58	neutral	0,41	neutral	0,43	2	neutral	0,78	neutral	0,39	neutral	-3	deleterious	0,76	low_impact	-1,34	medium_impact	0,31	medium_impact	0,09	0,57	0,8	14,76	12,06	N	0,21	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13133	13133	T	G	MI.20946	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	797	266	L	R	cTa/cGa	-7,16	0	0	probably_damaging	0,97	neutral	0,5	neutral	4,25	deleterious	-5,94	deleterious	-5,05	high_impact	4,29	neutral	0,62	neutral	0,28	deleterious	4,15	23,8	0,31	0,45	disease	0,95	disease	0,89	disease	0,74	disease	0,77	5	neutral	0,97	neutral	0,27	deleterious	2	deleterious	0,91	low_impact	-2,18	medium_impact	0,23	high_impact	2,72	0,47	0,8	14,76	12,06	N	0,37	N	0,96	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13133	13133	T	A	MI.20947	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	797	266	L	Q	cTa/cAa	-7,16	0	0	probably_damaging	0,98	neutral	0,48	neutral	4,25	deleterious	-5,61	deleterious	-4,99	high_impact	3,94	neutral	0,71	neutral	0,36	deleterious	4,04	23,7	0,32	0,5	disease	0,95	disease	0,81	disease	0,61	disease	0,77	5	neutral	0,98	neutral	0,25	deleterious	2	deleterious	0,85	low_impact	-2,35	medium_impact	0,21	high_impact	2,4	0,48	0,8	14,76	12,06	N	0,3	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13133	13133	T	C	MI.20948	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	797	266	L	P	cTa/cCa	-7,16	0	0	benign	0,23	neutral	0,32	neutral	4,28	deleterious	-6,21	deleterious	-5,85	medium_impact	3,48	neutral	0,65	damaging	0,27	deleterious	3,88	23,5	0,26	0,45	disease	0,96	disease	0,88	disease	0,75	disease	0,77	5	neutral	0,61	deleterious	0,55	neutral	-3	deleterious	0,91	medium_impact	-0,25	medium_impact	0,05	medium_impact	1,98	0,49	0,8	14,76	12,06	N	0,29	N	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13135	13135	G	A	MI.20949	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	799	267	A	T	Gca/Aca	-5,78	0	0,03	benign	0,01	neutral	0,49	neutral	4,62	neutral	-1,47	neutral	0,53	neutral_impact	0,42	neutral	0,9	neutral	0,97	neutral	0,97	10,47	0,64	0,7	disease	0,54	neutral	0,21	neutral	0,26	neutral	0,42	2	neutral	0,5	deleterious	0,74	neutral	-6	neutral	0,14	medium_impact	1,15	medium_impact	0,22	medium_impact	-0,82	0,74	0,85	15,26	13,11	N	0,44	N	0,04	polymorphism	1	0	rs200044200	.	.	.	.	.	.	.	.	G13135A	Possible HCM susceptibility	+	-	Reported	1
chrM	6009	6009	C	A	MI.2095	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	106	36	L	I	Ctt/Att	-20	0	0	probably_damaging	1	neutral	0,27	neutral	2,6	neutral	-1,73	neutral	-0,58	neutral_impact	0,48	damaging	0,58	damaging	0,23	deleterious	0,65	8,48	0,33	0,55	neutral	0,21	neutral	0,15	neutral	0,2	neutral	0,26	5	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,67	low_impact	-3,58	medium_impact	-0,05	medium_impact	-0,66	0,76	0,9	2,34	7,4	N	0,44	N	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13135	13135	G	T	MI.20950	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	799	267	A	S	Gca/Tca	-5,78	0	0,03	benign	0,27	neutral	0,51	neutral	4,62	neutral	-2,08	neutral	-0,4	neutral_impact	-0,66	neutral	0,74	neutral	0,69	deleterious	2,04	16,45	0,6	0,65	neutral	0,48	neutral	0,29	neutral	0,39	neutral	0,41	2	neutral	0,39	deleterious	0,62	neutral	-6	neutral	0,4	medium_impact	-0,34	medium_impact	0,24	low_impact	-1,81	0,88	0,9	15,26	13,11	N	0,31	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13135	13135	G	C	MI.20951	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	799	267	A	P	Gca/Cca	-5,78	0	0,03	possibly_damaging	0,73	neutral	0,26	neutral	4,56	neutral	-1,1	neutral	-1,47	neutral_impact	0,17	neutral	0,64	neutral	0,4	deleterious	3,71	23,3	0,24	0,45	disease	0,55	disease	0,74	disease	0,59	disease	0,67	3	neutral	0,81	neutral	0,27	neutral	-3	deleterious	0,75	low_impact	-1,16	medium_impact	-0,02	low_impact	-1,05	0,85	0,9	15,26	13,11	N	0,28	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13136	13136	C	A	MI.20952	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	800	267	A	E	gCa/gAa	-1,19	0	0	possibly_damaging	0,46	neutral	0,41	neutral	4,56	deleterious	-3,91	neutral	-1,45	low_impact	0,98	neutral	0,7	neutral	0,62	deleterious	4,14	23,8	0,2	0,45	disease	0,82	disease	0,62	disease	0,58	disease	0,67	3	neutral	0,55	deleterious	0,48	neutral	-3	deleterious	0,64	medium_impact	-0,68	medium_impact	0,15	medium_impact	-0,31	0,76	0,85	15,26	13,11	N	0,27	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13136	13136	C	G	MI.20953	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	800	267	A	G	gCa/gGa	-1,19	0	0	benign	0,34	neutral	0,39	neutral	4,55	neutral	-1,18	neutral	-2,29	low_impact	0,98	neutral	0,73	neutral	0,66	deleterious	2,33	18,37	0,4	0,5	disease	0,64	neutral	0,3	neutral	0,38	disease	0,59	2	neutral	0,54	deleterious	0,53	neutral	-6	deleterious	0,52	medium_impact	-0,47	medium_impact	0,13	medium_impact	-0,31	0,93	0,95	15,26	13,11	N	0,33	N	0,43	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13136	13136	C	T	MI.20954	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	800	267	A	V	gCa/gTa	-1,19	0	0	benign	0,12	neutral	0,54	neutral	4,63	neutral	-0,64	neutral	1,55	neutral_impact	-0,47	neutral	0,84	neutral	0,84	deleterious	2,74	21,1	0,63	0,7	neutral	0,47	neutral	0,34	neutral	0,28	neutral	0,47	1	neutral	0,37	deleterious	0,71	neutral	-6	neutral	0,37	medium_impact	0,08	medium_impact	0,27	low_impact	-1,63	0,81	0,85	15,26	13,11	N	0,26	N	0,14	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13138	13138	G	A	MI.20955	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	802	268	E	K	Gaa/Aaa	-1,42	0	0	probably_damaging	1	neutral	0,61	neutral	4,58	neutral	-0,65	neutral	-2,26	low_impact	1,36	neutral	0,78	damaging	0,19	deleterious	4,42	24,2	0,44	0,55	disease	0,71	disease	0,77	disease	0,6	disease	0,56	1	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,81	low_impact	-3,6	medium_impact	0,34	medium_impact	0,04	0,52	0,8	21,89	16,2	N	0,16	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13138	13138	G	C	MI.20956	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	802	268	E	Q	Gaa/Caa	-1,42	0	0	probably_damaging	1	neutral	0,48	neutral	4,57	neutral	-0,84	neutral	-1,1	neutral_impact	0,54	neutral	0,82	neutral	0,78	deleterious	2,1	16,87	0,67	0,7	disease	0,7	neutral	0,45	neutral	0,28	disease	0,62	2	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,21	medium_impact	-0,71	0,73	0,85	21,89	16,2	N	0,32	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13139	13139	A	G	MI.20957	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	803	268	E	G	gAa/gGa	-0,27	0	0	probably_damaging	1	neutral	0,46	neutral	4,51	neutral	-1,96	deleterious	-4,75	low_impact	1,03	neutral	0,83	damaging	0,19	deleterious	4,04	23,7	0,6	0,65	disease	0,7	disease	0,64	disease	0,65	disease	0,59	2	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,19	medium_impact	-0,26	0,48	0,8	21,89	16,2	N	0,25	N	0,71	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13139	13139	A	T	MI.20958	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	803	268	E	V	gAa/gTa	-0,27	0	0	probably_damaging	1	neutral	0,6	neutral	4,5	neutral	-2,44	deleterious	-4,71	low_impact	1,84	neutral	0,81	damaging	0,13	deleterious	3,99	23,6	0,34	0,5	disease	0,82	disease	0,75	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,81	low_impact	-3,6	medium_impact	0,33	medium_impact	0,48	0,68	0,85	21,89	16,2	N	0,18	N	0,73	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13139	13139	A	C	MI.20959	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	803	268	E	A	gAa/gCa	-0,27	0	0	probably_damaging	1	neutral	0,76	neutral	4,54	neutral	-1,27	deleterious	-3,82	neutral_impact	0,55	neutral	0,79	neutral	0,37	deleterious	3,5	23,1	0,51	0,6	disease	0,59	neutral	0,47	disease	0,53	disease	0,6	2	deleterious	1	neutral	0,38	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	0,51	medium_impact	-0,7	0,55	0,8	21,89	16,2	N	0,19	N	0,59	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6010	6010	T	A	MI.2096	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	107	36	L	H	cTt/cAt	-0,34	0	0	probably_damaging	1	deleterious	0	neutral	2,41	deleterious	-5,17	deleterious	-3,84	high_impact	4,52	damaging	0,59	damaging	0,05	deleterious	3,95	23,6	0,12	0,55	disease	0,84	disease	0,78	disease	0,6	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,07	0,63	0,9	2,34	7,4	N	0,37	N	0,83	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13140	13140	A	C	MI.20960	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	804	268	E	D	gaA/gaC	1,33	0	0	probably_damaging	1	neutral	0,42	neutral	4,54	neutral	-1,27	neutral	-2,02	low_impact	1,8	neutral	0,77	damaging	0,17	deleterious	3,64	23,2	0,58	0,65	disease	0,77	disease	0,58	neutral	0,45	disease	0,54	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,77	low_impact	-3,6	medium_impact	0,16	medium_impact	0,44	0,77	0,85	21,89	16,2	N	0,23	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13140	13140	A	T	MI.20961	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	804	268	E	D	gaA/gaT	1,33	0	0	probably_damaging	1	neutral	0,42	neutral	4,54	neutral	-1,27	neutral	-2,02	low_impact	1,8	neutral	0,77	damaging	0,17	deleterious	3,77	23,4	0,58	0,65	disease	0,77	disease	0,58	neutral	0,45	disease	0,54	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,77	low_impact	-3,6	medium_impact	0,16	medium_impact	0,44	0,77	0,85	21,89	16,2	N	0,24	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13141	13141	A	G	MI.20962	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	805	269	N	D	Aat/Gat	-1,65	0	0	benign	0,06	neutral	0,4	neutral	4,6	neutral	-0,74	deleterious	-2,99	low_impact	1,55	neutral	0,83	neutral	0,87	neutral	0,94	10,32	0,85	0,9	disease	0,53	disease	0,51	neutral	0,42	neutral	0,37	3	neutral	0,56	deleterious	0,67	neutral	-6	deleterious	0,52	medium_impact	0,39	medium_impact	0,14	medium_impact	0,21	0,35	0,8	9,95	16,38	N	0,34	N	0,25	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13141	13141	A	T	MI.20963	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	805	269	N	Y	Aat/Tat	-1,65	0	0	probably_damaging	0,95	neutral	1	neutral	4,58	neutral	-1,05	deleterious	-4,78	low_impact	1,05	neutral	0,85	neutral	0,65	deleterious	3,47	23	0,52	0,6	neutral	0,36	disease	0,66	disease	0,67	neutral	0,48	0	neutral	0,95	deleterious	0,53	neutral	-2	deleterious	0,7	low_impact	-1,96	high_impact	1,89	medium_impact	-0,24	0,28	0,8	9,95	16,38	N	0,19	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13141	13141	A	C	MI.20964	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	805	269	N	H	Aat/Cat	-1,65	0	0	probably_damaging	0,97	neutral	0,59	neutral	4,55	neutral	-2,11	neutral	-2,44	low_impact	1	neutral	0,82	neutral	0,96	neutral	1,75	14,7	0,68	0,7	disease	0,67	disease	0,56	neutral	0,43	neutral	0,38	2	neutral	0,96	neutral	0,31	neutral	-2	deleterious	0,73	low_impact	-2,18	medium_impact	0,32	medium_impact	-0,29	0,31	0,8	9,95	16,38	N	0,24	N	0,21	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13142	13142	A	C	MI.20965	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	806	269	N	T	aAt/aCt	-0,27	0	0	benign	0,1	neutral	0,59	neutral	4,59	neutral	-0,83	deleterious	-3,25	low_impact	0,9	neutral	0,89	neutral	0,97	deleterious	0,54	7,71	0,73	0,75	disease	0,53	neutral	0,42	neutral	0,29	neutral	0,44	1	neutral	0,32	deleterious	0,75	neutral	-6	deleterious	0,47	medium_impact	0,16	medium_impact	0,32	medium_impact	-0,38	0,31	0,8	9,95	16,38	N	0,32	N	0,17	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13142	13142	A	T	MI.20966	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	806	269	N	I	aAt/aTt	-0,27	0	0	possibly_damaging	0,78	neutral	0,5	neutral	4,57	neutral	-1,41	deleterious	-5,63	low_impact	1,87	neutral	0,8	neutral	0,53	deleterious	3,61	23,2	0,53	0,6	disease	0,85	disease	0,76	disease	0,61	disease	0,71	4	neutral	0,76	neutral	0,36	neutral	-3	deleterious	0,75	low_impact	-1,27	medium_impact	0,23	medium_impact	0,51	0,24	0,8	9,95	16,38	N	0,22	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13142	13142	A	G	MI.20967	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	806	269	N	S	aAt/aGt	-0,27	0	0	benign	0,1	neutral	0,65	neutral	4,72	neutral	0,75	deleterious	-2,77	neutral_impact	0,68	neutral	0,86	neutral	0,94	deleterious	-0,04	2,24	0,75	0,8	neutral	0,48	neutral	0,46	neutral	0,35	neutral	0,42	2	neutral	0,25	deleterious	0,78	neutral	-6	neutral	0,21	medium_impact	0,16	medium_impact	0,38	medium_impact	-0,58	0,1	0,8	9,95	16,38	N	0,28	N	0,34	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13143	13143	T	G	MI.20968	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	807	269	N	K	aaT/aaG	-0,04	0	0,01	possibly_damaging	0,56	neutral	0,59	neutral	4,62	neutral	-0,4	deleterious	-3,73	low_impact	1,47	neutral	0,81	neutral	0,62	deleterious	2,5	19,45	0,81	0,85	disease	0,6	disease	0,65	neutral	0,47	neutral	0,38	2	neutral	0,5	deleterious	0,52	neutral	-3	deleterious	0,6	medium_impact	-0,85	medium_impact	0,32	medium_impact	0,14	0,37	0,8	9,95	16,38	N	0,21	N	0,74	polymorphism	1	0,06	rs386829174	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13143	13143	T	A	MI.20969	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	807	269	N	K	aaT/aaA	-0,04	0	0,01	possibly_damaging	0,56	neutral	0,59	neutral	4,62	neutral	-0,4	deleterious	-3,73	low_impact	1,47	neutral	0,81	neutral	0,62	deleterious	2,88	21,8	0,81	0,85	disease	0,6	disease	0,65	neutral	0,47	neutral	0,38	2	neutral	0,5	deleterious	0,52	neutral	-3	deleterious	0,6	medium_impact	-0,85	medium_impact	0,32	medium_impact	0,14	0,37	0,8	9,95	16,38	N	0,22	N	0,74	polymorphism	1	0,06	rs386829174	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6010	6010	T	G	MI.2097	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	107	36	L	R	cTt/cGt	-0,34	0	0	probably_damaging	1	deleterious	0	neutral	2,41	deleterious	-4,1	deleterious	-3,4	high_impact	4,52	damaging	0,55	damaging	0,06	deleterious	4	23,6	0,1	0,55	disease	0,79	disease	0,86	disease	0,64	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,07	0,68	0,9	2,34	7,4	N	0,39	N	0,9	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13144	13144	A	C	MI.20970	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	808	270	S	R	Agc/Cgc	-7,38	0	0	benign	0,26	neutral	0,52	neutral	4,51	deleterious	-3,05	neutral	-1,07	high_impact	3,61	damaging	0,59	neutral	0,47	deleterious	1,92	15,69	0,38	0,5	disease	0,71	disease	0,8	disease	0,72	disease	0,73	5	neutral	0,38	deleterious	0,63	neutral	-2	deleterious	0,51	medium_impact	-0,32	medium_impact	0,25	high_impact	2,1	0,74	0,85	5,64	7,11	N	0,29	N	0,24	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13144	13144	A	G	MI.20971	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	808	270	S	G	Agc/Ggc	-7,38	0	0	benign	0,18	neutral	0,39	neutral	4,53	neutral	-1,95	neutral	-1,03	medium_impact	2,86	neutral	0,67	neutral	0,59	neutral	1,53	13,47	0,52	0,6	neutral	0,33	neutral	0,49	disease	0,55	disease	0,56	1	neutral	0,53	deleterious	0,61	neutral	-3	neutral	0,2	medium_impact	-0,12	medium_impact	0,13	medium_impact	1,41	0,76	0,85	5,64	7,11	N	0,33	N	0,27	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13144	13144	A	T	MI.20972	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	808	270	S	C	Agc/Tgc	-7,38	0	0	possibly_damaging	0,89	neutral	0,06	neutral	4,47	deleterious	-5,63	deleterious	-3,65	medium_impact	2,92	neutral	0,66	neutral	0,43	deleterious	3,21	22,7	0,46	0,55	disease	0,95	disease	0,64	neutral	0,44	disease	0,75	5	neutral	0,98	neutral	0,09	NA	0	deleterious	0,76	low_impact	-1,61	medium_impact	-0,43	medium_impact	1,46	0,63	0,8	5,64	7,11	N	0,33	N	0,7	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13145	13145	G	C	MI.20973	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	809	270	S	T	aGc/aCc	4,31	0,98	0,01	benign	0,18	neutral	0,58	neutral	4,54	neutral	-1,28	neutral	-0,99	low_impact	0,98	neutral	0,7	neutral	0,67	neutral	1,56	13,62	0,49	0,55	disease	0,55	neutral	0,38	neutral	0,41	disease	0,61	2	neutral	0,31	deleterious	0,7	neutral	-6	neutral	0,33	medium_impact	-0,12	medium_impact	0,31	medium_impact	-0,31	0,66	0,8	5,64	7,11	N	0,48	N	0,21	polymorphism	1	0,02	rs386829175	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13145	13145	G	A	MI.20974	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	809	270	S	N	aGc/aAc	4,31	0,98	0,01	benign	0,01	neutral	0,51	neutral	4,6	neutral	-2,49	neutral	4,16	neutral_impact	0,44	neutral	0,85	neutral	0,96	neutral	-1,05	0,01	0,83	0,85	neutral	0,4	neutral	0,08	neutral	0,18	neutral	0,29	4	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,13	medium_impact	1,15	medium_impact	0,24	medium_impact	-0,8	0,67	0,85	5,64	7,11	P	0,55	P	0	polymorphism	1	0,01	rs386829175	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13145	13145	G	T	MI.20975	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	809	270	S	I	aGc/aTc	4,31	0,98	0,01	possibly_damaging	0,62	neutral	0,2	neutral	4,54	deleterious	-3,16	deleterious	-3,69	low_impact	1,86	neutral	0,68	neutral	0,58	deleterious	3,8	23,4	0,49	0,55	disease	0,79	disease	0,72	disease	0,56	disease	0,68	4	neutral	0,81	neutral	0,29	neutral	-3	deleterious	0,61	medium_impact	-0,95	medium_impact	-0,1	medium_impact	0,5	0,77	0,85	5,64	7,11	N	0,49	N	0,57	polymorphism	1	0,06	rs386829175	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13147	13147	C	A	MI.20976	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	811	271	P	T	Cca/Aca	-2,11	0	0	benign	0,01	neutral	0,61	neutral	4,61	neutral	-2,24	neutral	-0,32	low_impact	1,45	neutral	0,88	neutral	0,96	deleterious	0,5	7,45	0,54	0,6	disease	0,8	neutral	0,2	neutral	0,22	disease	0,53	1	neutral	0,37	deleterious	0,8	neutral	-6	neutral	0,26	medium_impact	1,15	medium_impact	0,34	medium_impact	0,12	0,7	0,85	30,35	19,69	N	0,33	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13147	13147	C	T	MI.20977	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	811	271	P	S	Cca/Tca	-2,11	0	0	benign	0,01	neutral	0,77	neutral	4,62	neutral	-1,82	neutral	0,31	low_impact	1,49	neutral	0,86	neutral	0,95	deleterious	0,39	6,52	0,58	0,65	disease	0,56	neutral	0,22	neutral	0,21	disease	0,54	1	neutral	0,21	deleterious	0,88	neutral	-6	neutral	0,13	medium_impact	1,15	medium_impact	0,52	medium_impact	0,16	0,25	0,8	30,35	19,69	N	0,34	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13147	13147	C	G	MI.20978	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	811	271	P	A	Cca/Gca	-2,11	0	0	benign	0,05	neutral	0,8	neutral	4,62	neutral	-1,3	neutral	-0,48	medium_impact	2,06	neutral	0,82	neutral	0,82	neutral	-0,1	1,75	0,52	0,6	disease	0,62	neutral	0,16	neutral	0,39	neutral	0,42	2	neutral	0,12	deleterious	0,88	neutral	-3	neutral	0,18	medium_impact	0,47	medium_impact	0,57	medium_impact	0,68	0,83	0,85	30,35	19,69	N	0,29	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13148	13148	C	G	MI.20979	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	812	271	P	R	cCa/cGa	-1,88	0	0	benign	0,26	neutral	0,54	neutral	4,58	deleterious	-3	neutral	0,91	medium_impact	3,19	neutral	0,81	neutral	0,6	deleterious	0,76	9,23	0,45	0,55	disease	0,69	neutral	0,5	disease	0,51	disease	0,52	0	neutral	0,35	deleterious	0,64	neutral	-3	neutral	0,38	medium_impact	-0,32	medium_impact	0,27	medium_impact	1,71	0,61	0,8	30,35	19,69	N	0,27	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6010	6010	T	C	MI.2098	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	107	36	L	P	cTt/cCt	-0,34	0	0	probably_damaging	1	deleterious	0	neutral	2,41	deleterious	-5,28	deleterious	-3,85	high_impact	3,97	damaging	0,5	damaging	0,07	deleterious	3,69	23,3	0,12	0,55	disease	0,84	disease	0,86	disease	0,66	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	2,57	0,68	0,9	2,34	7,4	N	0,29	N	0,83	disease_causing	0,99	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13148	13148	C	T	MI.20980	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	812	271	P	L	cCa/cTa	-1,88	0	0	benign	0	neutral	0,43	neutral	4,6	deleterious	-3,31	neutral	-1,09	low_impact	1,7	neutral	0,83	neutral	0,81	neutral	1,45	13,04	0,55	0,6	disease	0,69	neutral	0,38	neutral	0,4	disease	0,63	3	neutral	0,56	deleterious	0,72	neutral	-6	neutral	0,33	high_impact	2,1	medium_impact	0,17	medium_impact	0,35	0,66	0,8	30,35	19,69	N	0,36	N	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13148	13148	C	A	MI.20981	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	812	271	P	Q	cCa/cAa	-1,88	0	0	benign	0,02	neutral	0,61	neutral	4,59	neutral	-2,31	neutral	1,28	low_impact	0,83	neutral	0,82	neutral	0,94	neutral	-0,6	0,12	0,36	0,5	disease	0,71	neutral	0,15	neutral	0,21	neutral	0,38	3	neutral	0,36	deleterious	0,8	neutral	-6	neutral	0,14	medium_impact	0,86	medium_impact	0,34	medium_impact	-0,45	0,61	0,8	30,35	19,69	N	0,31	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13150	13150	C	A	MI.20982	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	814	272	L	M	Cta/Ata	-4,4	0	0	benign	0,32	neutral	0,35	neutral	4,51	neutral	-2,43	neutral	-0,44	low_impact	0,96	neutral	0,82	neutral	0,96	deleterious	2,18	17,41	0,39	0,5	disease	0,75	neutral	0,2	neutral	0,33	disease	0,53	1	neutral	0,58	deleterious	0,52	neutral	-6	deleterious	0,66	medium_impact	-0,44	medium_impact	0,08	medium_impact	-0,33	0,72	0,85	20,07	13,68	N	0,38	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13150	13150	C	G	MI.20983	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	814	272	L	V	Cta/Gta	-4,4	0	0	possibly_damaging	0,44	neutral	0,53	neutral	4,59	neutral	-1,09	neutral	-0,34	low_impact	0,99	neutral	0,87	neutral	0,88	deleterious	0,16	4,23	0,42	0,55	neutral	0,5	neutral	0,26	neutral	0,35	neutral	0,37	3	neutral	0,44	deleterious	0,55	neutral	-3	neutral	0,35	medium_impact	-0,65	medium_impact	0,26	medium_impact	-0,3	0,48	0,8	20,07	13,68	N	0,31	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13151	13151	T	C	MI.20984	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	815	272	L	P	cTa/cCa	-0,73	0	0	benign	0,08	neutral	0,32	neutral	4,51	deleterious	-3,69	neutral	-1,85	low_impact	1,64	neutral	0,88	neutral	0,83	deleterious	0,66	8,58	0,24	0,45	neutral	0,39	disease	0,77	disease	0,57	disease	0,54	1	neutral	0,64	deleterious	0,62	neutral	-6	neutral	0,22	medium_impact	0,26	medium_impact	0,05	medium_impact	0,3	0,52	0,8	20,07	13,68	N	0,3	N	0,61	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13151	13151	T	G	MI.20985	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	815	272	L	R	cTa/cGa	-0,73	0	0	possibly_damaging	0,83	neutral	0,51	neutral	4,54	neutral	-2,26	neutral	-1,84	medium_impact	3	neutral	0,69	neutral	0,45	deleterious	2,4	18,8	0,36	0,5	disease	0,8	disease	0,76	disease	0,64	disease	0,73	5	neutral	0,81	neutral	0,34	NA	0	deleterious	0,62	low_impact	-1,4	medium_impact	0,24	medium_impact	1,54	0,61	0,8	20,07	13,68	N	0,27	N	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13151	13151	T	A	MI.20986	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	815	272	L	Q	cTa/cAa	-0,73	0	0	possibly_damaging	0,87	neutral	0,65	neutral	4,55	neutral	-1,91	neutral	-1,71	low_impact	1,72	neutral	0,77	neutral	0,71	deleterious	2,55	19,79	0,31	0,45	disease	0,6	disease	0,57	neutral	0,49	neutral	0,46	1	neutral	0,85	neutral	0,39	neutral	-3	deleterious	0,61	low_impact	-1,53	medium_impact	0,38	medium_impact	0,37	0,58	0,8	20,07	13,68	N	0,23	N	0,27	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13153	13153	A	C	MI.20987	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	817	273	I	L	Atc/Ctc	-8,53	0	0	benign	0,03	neutral	1	neutral	4,65	neutral	0,52	neutral	-1,17	neutral_impact	0,19	neutral	0,84	neutral	0,82	deleterious	0,47	7,2	0,35	0,5	neutral	0,4	neutral	0,39	disease	0,54	neutral	0,49	0	neutral	0,03	deleterious	0,99	neutral	-6	neutral	0,2	medium_impact	0,69	high_impact	1,89	low_impact	-1,03	0,55	0,8	6,14	9,22	N	0,26	N	0,68	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13153	13153	A	G	MI.20988	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	817	273	I	V	Atc/Gtc	-8,53	0	0	benign	0,03	neutral	0,45	neutral	4,61	neutral	0,55	neutral	-0,4	neutral_impact	0,26	neutral	0,87	neutral	0,96	neutral	-0,9	0,03	0,62	0,65	disease	0,51	neutral	0,18	neutral	0,38	neutral	0,26	5	neutral	0,52	deleterious	0,71	neutral	-6	neutral	0,12	medium_impact	0,69	medium_impact	0,18	medium_impact	-0,97	0,39	0,8	6,14	9,22	N	0,36	N	0,55	polymorphism	1	0,01	rs878957731	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13153	13153	A	T	MI.20989	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	817	273	I	F	Atc/Ttc	-8,53	0	0	possibly_damaging	0,72	neutral	0,47	neutral	4,51	neutral	-0,36	deleterious	-2,58	neutral_impact	0,24	neutral	0,78	neutral	0,5	deleterious	2,49	19,42	0,45	0,55	disease	0,73	disease	0,57	disease	0,61	disease	0,58	2	neutral	0,7	neutral	0,38	neutral	-3	deleterious	0,66	low_impact	-1,14	medium_impact	0,2	medium_impact	-0,98	0,63	0,8	6,14	9,22	N	0,22	N	0,54	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6012	6012	A	G	MI.2099	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	109	37	I	V	Att/Gtt	-4,5	0	0	probably_damaging	0,95	neutral	0,11	neutral	2,72	neutral	-0,99	neutral	-0,56	medium_impact	2,95	damaging	0,57	neutral	0,62	deleterious	2,86	21,7	0,42	0,55	neutral	0,44	neutral	0,47	neutral	0,45	neutral	0,44	1	deleterious	0,98	neutral	0,08	deleterious	1	deleterious	0,63	low_impact	-1,96	medium_impact	-0,31	medium_impact	1,63	0,65	0,9	1,75	6,65	N	0,49	N	0,23	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13154	13154	T	A	MI.20990	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	818	273	I	N	aTc/aAc	-0,27	0	0	possibly_damaging	0,83	neutral	0,51	neutral	4,46	deleterious	-3,56	deleterious	-4,89	low_impact	1,55	neutral	0,73	neutral	0,41	deleterious	4,45	24,2	0,36	0,5	disease	0,66	disease	0,74	disease	0,6	disease	0,71	4	neutral	0,81	neutral	0,34	neutral	-3	deleterious	0,71	low_impact	-1,4	medium_impact	0,24	medium_impact	0,21	0,59	0,8	6,14	9,22	N	0,26	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13154	13154	T	C	MI.20991	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	818	273	I	T	aTc/aCc	-0,27	0	0	benign	0,04	neutral	0,87	neutral	4,5	neutral	-1	deleterious	-2,99	neutral_impact	0,33	neutral	0,83	neutral	0,8	deleterious	0,63	8,35	0,49	0,55	neutral	0,39	neutral	0,41	neutral	0,41	neutral	0,46	1	neutral	0,05	deleterious	0,92	neutral	-6	neutral	0,36	medium_impact	0,57	medium_impact	0,69	medium_impact	-0,9	0,58	0,8	6,14	9,22	N	0,24	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13154	13154	T	G	MI.20992	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	818	273	I	S	aTc/aGc	-0,27	0	0	possibly_damaging	0,48	neutral	0,7	neutral	4,51	neutral	-1,58	deleterious	-3,78	neutral_impact	0,53	neutral	0,77	neutral	0,76	deleterious	2,51	19,53	0,4	0,5	neutral	0,37	disease	0,61	neutral	0,43	neutral	0,46	1	neutral	0,38	deleterious	0,61	neutral	-3	neutral	0,39	medium_impact	-0,71	medium_impact	0,44	medium_impact	-0,72	0,51	0,8	6,14	9,22	N	0,22	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13155	13155	C	A	MI.20993	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	819	273	I	M	atC/atA	-0,73	0	0	possibly_damaging	0,83	neutral	0,49	neutral	4,55	neutral	-1,17	neutral	-1,62	neutral_impact	0,46	neutral	0,84	neutral	0,95	deleterious	2,53	19,65	0,49	0,55	neutral	0,36	neutral	0,35	neutral	0,38	neutral	0,45	1	neutral	0,82	neutral	0,33	neutral	-3	deleterious	0,59	low_impact	-1,4	medium_impact	0,22	medium_impact	-0,78	0,68	0,85	6,14	9,22	N	0,32	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13155	13155	C	G	MI.20994	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	819	273	I	M	atC/atG	-0,73	0	0	possibly_damaging	0,83	neutral	0,49	neutral	4,55	neutral	-1,17	neutral	-1,62	neutral_impact	0,46	neutral	0,84	neutral	0,95	deleterious	2,09	16,8	0,49	0,55	neutral	0,36	neutral	0,35	neutral	0,38	neutral	0,45	1	neutral	0,82	neutral	0,33	neutral	-3	deleterious	0,59	low_impact	-1,4	medium_impact	0,22	medium_impact	-0,78	0,68	0,85	6,14	9,22	N	0,32	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13156	13156	C	A	MI.20995	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	820	274	Q	K	Caa/Aaa	-6,24	0	0	probably_damaging	1	neutral	0,91	neutral	4,63	neutral	-1,13	neutral	-2,13	neutral_impact	0,8	neutral	0,79	neutral	0,6	deleterious	2,74	21	0,55	0,6	disease	0,54	disease	0,64	disease	0,68	disease	0,67	3	deleterious	1	neutral	0,46	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,79	medium_impact	-0,47	0,75	0,85	20,73	16,44	N	0,18	N	0,62	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13156	13156	C	G	MI.20996	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	820	274	Q	E	Caa/Gaa	-6,24	0	0	probably_damaging	1	neutral	1	neutral	4,6	neutral	-0,96	neutral	-1,98	low_impact	1,45	neutral	0,67	neutral	0,47	deleterious	3,08	22,5	0,6	0,65	disease	0,59	disease	0,6	disease	0,68	disease	0,73	5	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,76	low_impact	-3,6	high_impact	1,89	medium_impact	0,12	0,75	0,85	20,73	16,44	N	0,2	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13157	13157	A	G	MI.20997	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	821	274	Q	R	cAa/cGa	-0,27	0	0	probably_damaging	1	neutral	0,51	neutral	4,61	neutral	-0,85	neutral	-2,17	low_impact	1,07	neutral	0,74	neutral	0,49	deleterious	2,3	18,16	0,7	0,75	disease	0,7	disease	0,67	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,82	low_impact	-3,6	medium_impact	0,24	medium_impact	-0,23	0,68	0,85	20,73	16,44	N	0,24	N	0,54	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13157	13157	A	C	MI.20998	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	821	274	Q	P	cAa/cCa	-0,27	0	0	probably_damaging	1	neutral	0,28	neutral	4,54	neutral	-2,64	deleterious	-3,64	low_impact	1,24	damaging	0,57	neutral	0,39	deleterious	3,33	22,9	0,3	0,45	neutral	0,49	disease	0,85	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,81	low_impact	-3,6	medium_impact	0,01	medium_impact	-0,07	0,7	0,85	20,73	16,44	N	0,29	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13157	13157	A	T	MI.20999	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	821	274	Q	L	cAa/cTa	-0,27	0	0	probably_damaging	1	neutral	0,46	neutral	4,66	neutral	0,2	neutral	-2,12	neutral_impact	-1,6	neutral	0,75	neutral	0,89	neutral	1,1	11,2	0,39	0,5	disease	0,56	neutral	0,19	neutral	0,32	neutral	0,44	1	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,19	low_impact	-2,66	0,38	0,8	20,73	16,44	N	0,3	N	0,49	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8535	8535	A	C	MI.21	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	9	3	E	D	gaA/gaC	4,06	1	0	probably_damaging	0,95	neutral	0,24	neutral	4,64	neutral	-0,82	neutral	-1,77	low_impact	1,61	neutral	0,84	neutral	0,46	deleterious	3,66	23,2	0,62	0,7	disease	0,61	neutral	0,13	neutral	0,18	neutral	0,41	2	neutral	0,96	neutral	0,15	neutral	-2	deleterious	0,64	low_impact	-1,97	medium_impact	0,01	medium_impact	0,28	0,92	0,95	15,93	14,48	P	0,56	P	0,87	polymorphism	0,9	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8624	8624	C	T	MI.210	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	98	33	T	I	aCc/aTc	-2,65	0	0	benign	0,17	neutral	0,3	neutral	4,24	neutral	-1,66	deleterious	-4,14	low_impact	1,88	neutral	0,85	neutral	0,64	deleterious	1,99	16,17	0,5	0,65	neutral	0,42	disease	0,62	disease	0,59	disease	0,66	3	neutral	0,65	deleterious	0,57	neutral	-6	neutral	0,28	medium_impact	-0,1	medium_impact	0,08	medium_impact	0,51	0,4	0,9	19,47	19,69	N	0,36	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6012	6012	A	T	MI.2100	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	109	37	I	F	Att/Ttt	-4,5	0	0	probably_damaging	1	deleterious	0	neutral	2,6	neutral	-1,56	neutral	-2,36	high_impact	4,1	damaging	0,58	neutral	0,38	deleterious	3,62	23,2	0,23	0,55	disease	0,75	disease	0,8	neutral	0,49	disease	0,62	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,69	0,79	0,9	1,75	6,65	N	0,36	N	0,85	disease_causing	0,53	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13158	13158	A	T	MI.21000	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	822	274	Q	H	caA/caT	0,87	0	0	probably_damaging	1	neutral	0,15	neutral	4,58	neutral	-2,07	deleterious	-3,12	low_impact	1,53	neutral	0,74	neutral	0,55	deleterious	3,52	23,1	0,66	0,7	disease	0,57	neutral	0,46	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	-0,18	medium_impact	0,2	0,76	0,85	20,73	16,44	N	0,36	N	0,64	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13158	13158	A	C	MI.21001	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	822	274	Q	H	caA/caC	0,87	0	0	probably_damaging	1	neutral	0,15	neutral	4,58	neutral	-2,07	deleterious	-3,12	low_impact	1,53	neutral	0,74	neutral	0,55	deleterious	3,3	22,9	0,66	0,7	disease	0,57	neutral	0,46	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	-0,18	medium_impact	0,2	0,76	0,85	20,73	16,44	N	0,36	N	0,64	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13159	13159	A	C	MI.21002	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	823	275	T	P	Act/Cct	-1,19	0	0	possibly_damaging	0,9	neutral	0,2	neutral	4,61	neutral	-0,64	deleterious	-4,78	low_impact	1,64	neutral	0,67	neutral	0,41	deleterious	3,36	22,9	0,25	0,45	disease	0,87	disease	0,85	disease	0,77	disease	0,74	5	neutral	0,94	neutral	0,15	neutral	-3	deleterious	0,84	low_impact	-1,65	medium_impact	-0,1	medium_impact	0,3	0,76	0,85	12,77	12,77	N	0,32	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13159	13159	A	T	MI.21003	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	823	275	T	S	Act/Tct	-1,19	0	0	benign	0,09	neutral	0,58	neutral	4,67	neutral	0,35	deleterious	-2,58	neutral_impact	0,34	neutral	0,85	neutral	0,96	deleterious	1,84	15,24	0,57	0,65	disease	0,72	neutral	0,3	neutral	0,43	disease	0,6	2	neutral	0,33	deleterious	0,75	neutral	-6	deleterious	0,73	medium_impact	0,21	medium_impact	0,31	medium_impact	-0,89	0,63	0,8	12,77	12,77	N	0,3	N	0,19	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13159	13159	A	G	MI.21004	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	823	275	T	A	Act/Gct	-1,19	0	0	possibly_damaging	0,54	neutral	0,56	neutral	4,63	neutral	-0,31	deleterious	-3,79	medium_impact	2,1	neutral	0,73	neutral	0,62	deleterious	3,32	22,9	0,64	0,7	disease	0,61	neutral	0,48	disease	0,65	disease	0,59	2	neutral	0,5	deleterious	0,51	NA	0	deleterious	0,73	medium_impact	-0,81	medium_impact	0,29	medium_impact	0,72	0,51	0,8	12,77	12,77	N	0,27	N	0,77	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13160	13160	C	T	MI.21005	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	824	275	T	I	aCt/aTt	2,25	0	0	probably_damaging	0,93	neutral	0,47	neutral	4,65	neutral	0,15	deleterious	-4,94	low_impact	1,6	neutral	0,71	neutral	0,54	deleterious	3,87	23,5	0,55	0,6	neutral	0,36	disease	0,71	disease	0,64	disease	0,51	0	neutral	0,93	neutral	0,27	neutral	-2	deleterious	0,72	low_impact	-1,81	medium_impact	0,2	medium_impact	0,26	0,69	0,85	12,77	12,77	N	0,29	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13160	13160	C	G	MI.21006	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	824	275	T	S	aCt/aGt	2,25	0	0	benign	0,09	neutral	0,58	neutral	4,67	neutral	0,35	deleterious	-2,58	neutral_impact	0,34	neutral	0,85	neutral	0,96	deleterious	2,2	17,49	0,57	0,65	disease	0,72	neutral	0,3	neutral	0,43	disease	0,6	2	neutral	0,33	deleterious	0,75	neutral	-6	deleterious	0,73	medium_impact	0,21	medium_impact	0,31	medium_impact	-0,89	0,63	0,8	12,77	12,77	N	0,31	N	0,19	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13160	13160	C	A	MI.21007	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	824	275	T	N	aCt/aAt	2,25	0	0	benign	0,05	neutral	0,41	neutral	4,7	neutral	0,73	deleterious	-3,52	low_impact	1,36	neutral	0,79	neutral	0,65	deleterious	3,68	23,3	0,66	0,7	disease	0,9	disease	0,73	disease	0,59	disease	0,68	4	neutral	0,55	deleterious	0,68	neutral	-6	deleterious	0,79	medium_impact	0,47	medium_impact	0,15	medium_impact	0,04	0,77	0,85	12,77	12,77	N	0,25	N	0,38	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13162	13162	C	A	MI.21008	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	826	276	L	M	Cta/Ata	-14,5	0	0	possibly_damaging	0,61	neutral	0,29	neutral	4,45	neutral	-2,6	neutral	-0,42	low_impact	0,94	neutral	0,86	neutral	0,95	deleterious	2,28	18,02	0,4	0,5	disease	0,61	neutral	0,17	neutral	0,31	neutral	0,41	2	neutral	0,73	neutral	0,34	neutral	-3	deleterious	0,67	medium_impact	-0,93	medium_impact	0,02	medium_impact	-0,34	0,7	0,85	18,08	15,31	N	0,45	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13162	13162	C	G	MI.21009	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	826	276	L	V	Cta/Gta	-14,5	0	0	possibly_damaging	0,73	neutral	0,53	neutral	4,61	neutral	-0,43	neutral	-1,33	neutral_impact	0,49	neutral	0,88	neutral	0,97	neutral	1,11	11,27	0,36	0,5	disease	0,61	neutral	0,14	neutral	0,28	neutral	0,32	4	neutral	0,69	neutral	0,4	neutral	-3	deleterious	0,67	low_impact	-1,16	medium_impact	0,26	medium_impact	-0,76	0,66	0,8	18,08	15,31	N	0,33	N	0,19	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6012	6012	A	C	MI.2101	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	109	37	I	L	Att/Ctt	-4,5	0	0	probably_damaging	0,98	deleterious	0	neutral	2,74	neutral	-0,92	neutral	-1,16	high_impact	3,75	neutral	0,61	neutral	0,45	deleterious	3,65	23,2	0,28	0,55	neutral	0,25	disease	0,68	neutral	0,41	disease	0,51	0	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,62	low_impact	-2,35	low_impact	-1,48	high_impact	2,36	0,68	0,9	1,75	6,65	N	0,5	N	0,61	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13163	13163	T	C	MI.21010	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	827	276	L	P	cTa/cCa	-8,53	0	0	probably_damaging	0,98	neutral	0,22	neutral	4,45	deleterious	-4	deleterious	-4,36	medium_impact	2,56	damaging	0,57	neutral	0,4	deleterious	3,78	23,4	0,08	0,35	disease	0,96	disease	0,76	disease	0,67	disease	0,78	6	deleterious	0,98	neutral	0,12	deleterious	1	deleterious	0,86	low_impact	-2,35	medium_impact	-0,07	medium_impact	1,14	0,61	0,8	18,08	15,31	N	0,27	N	0,85	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13163	13163	T	A	MI.21011	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	827	276	L	Q	cTa/cAa	-8,53	0	0	probably_damaging	0,98	neutral	0,35	neutral	4,42	deleterious	-4,85	deleterious	-3,51	high_impact	3,54	neutral	0,74	neutral	0,58	deleterious	3,91	23,5	0,11	0,4	disease	0,95	disease	0,52	neutral	0,47	disease	0,77	5	neutral	0,98	neutral	0,19	deleterious	2	deleterious	0,8	low_impact	-2,35	medium_impact	0,08	high_impact	2,03	0,69	0,85	18,08	15,31	N	0,36	N	0,66	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13163	13163	T	G	MI.21012	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	827	276	L	R	cTa/cGa	-8,53	0	0	probably_damaging	0,97	neutral	0,34	neutral	4,43	deleterious	-5,04	deleterious	-3,74	high_impact	3,54	neutral	0,67	neutral	0,47	deleterious	4,01	23,6	0,08	0,35	disease	0,94	disease	0,67	disease	0,62	disease	0,77	5	neutral	0,97	neutral	0,19	deleterious	2	deleterious	0,85	low_impact	-2,18	medium_impact	0,07	high_impact	2,03	0,58	0,8	18,08	15,31	N	0,31	N	0,64	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13165	13165	A	C	MI.21013	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	829	277	T	P	Aca/Cca	-8,53	0	0	probably_damaging	0,93	neutral	0,23	neutral	4,56	neutral	-1,82	deleterious	-3,17	medium_impact	2,19	neutral	0,6	neutral	0,35	deleterious	3,4	23	0,19	0,45	neutral	0,5	disease	0,82	disease	0,68	disease	0,77	5	neutral	0,95	neutral	0,15	deleterious	1	deleterious	0,75	low_impact	-1,81	medium_impact	-0,06	medium_impact	0,8	0,74	0,85	10,95	13,27	N	0,25	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13165	13165	A	G	MI.21014	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	829	277	T	A	Aca/Gca	-8,53	0	0	benign	0,05	neutral	0,56	neutral	4,61	neutral	0,45	neutral	-1,7	neutral_impact	0,32	neutral	0,82	neutral	0,94	deleterious	0,23	4,96	0,53	0,6	neutral	0,46	neutral	0,28	neutral	0,47	neutral	0,44	1	neutral	0,38	deleterious	0,76	neutral	-6	neutral	0,17	medium_impact	0,47	medium_impact	0,29	medium_impact	-0,91	0,52	0,8	10,95	13,27	N	0,3	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13165	13165	A	T	MI.21015	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	829	277	T	S	Aca/Tca	-8,53	0	0	possibly_damaging	0,64	neutral	0,59	neutral	4,59	neutral	-0,99	neutral	-1,49	low_impact	1,16	neutral	0,78	neutral	0,84	neutral	1,66	14,16	0,46	0,55	disease	0,7	neutral	0,39	neutral	0,46	disease	0,63	3	neutral	0,59	deleterious	0,48	neutral	-3	deleterious	0,52	medium_impact	-0,98	medium_impact	0,32	medium_impact	-0,14	0,8	0,85	10,95	13,27	N	0,26	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13166	13166	C	T	MI.21016	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	830	277	T	M	aCa/aTa	0,18	0	0	probably_damaging	0,95	neutral	0,28	neutral	4,63	neutral	0,33	neutral	-1,26	neutral_impact	0,62	neutral	0,83	neutral	0,95	deleterious	2,47	19,27	0,42	0,5	disease	0,77	neutral	0,5	neutral	0,37	disease	0,51	0	neutral	0,96	neutral	0,17	neutral	-2	deleterious	0,73	low_impact	-1,96	medium_impact	0,01	medium_impact	-0,64	0,8	0,85	10,95	13,27	N	0,33	N	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13166	13166	C	A	MI.21017	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	830	277	T	K	aCa/aAa	0,18	0	0	possibly_damaging	0,82	neutral	0,3	neutral	4,57	neutral	-2,44	deleterious	-2,92	medium_impact	2,19	neutral	0,74	neutral	0,42	deleterious	4,19	23,8	0,2	0,45	disease	0,85	disease	0,7	disease	0,67	disease	0,77	5	neutral	0,85	neutral	0,24	NA	0	deleterious	0,72	low_impact	-1,37	medium_impact	0,03	medium_impact	0,8	0,73	0,85	10,95	13,27	N	0,27	N	0,89	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13168	13168	C	A	MI.21018	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	832	278	L	M	Cta/Ata	-6,7	0	0	probably_damaging	1	neutral	0,27	neutral	4,43	neutral	-2,16	neutral	-1,3	medium_impact	2,54	neutral	0,71	damaging	0,28	deleterious	3,72	23,3	0,4	0,5	NA	NA	disease	0,52	disease	0,57	neutral	0,43	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,01	medium_impact	1,12	0,62	0,8	12,94	6,99	N	0,33	N	0,89	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13168	13168	C	G	MI.21019	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	832	278	L	V	Cta/Gta	-6,7	0	0	probably_damaging	1	neutral	0,57	neutral	4,55	neutral	-1,28	deleterious	-2,5	medium_impact	2,58	neutral	0,66	damaging	0,09	deleterious	3,44	23	0,39	0,5	NA	NA	disease	0,51	disease	0,66	disease	0,54	1	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,3	medium_impact	1,15	0,58	0,8	12,94	6,99	N	0,2	N	0,81	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6013	6013	T	C	MI.2102	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	110	37	I	T	aTt/aCt	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,59	neutral	-2,47	deleterious	-2,93	high_impact	4,65	neutral	0,63	neutral	0,4	deleterious	3,11	22,5	0,29	0,55	disease	0,82	disease	0,77	neutral	0,47	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,2	0,57	0,9	1,75	6,65	P	0,57	P	0,76	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13169	13169	T	G	MI.21020	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	833	278	L	R	cTa/cGa	0,41	0,05	0	probably_damaging	1	neutral	0,29	neutral	4,37	deleterious	-4,9	deleterious	-5,11	high_impact	4,54	neutral	0,62	damaging	0,08	deleterious	4,15	23,8	0,17	0,45	NA	NA	disease	0,87	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,02	high_impact	2,94	0,55	0,8	12,94	6,99	N	0,55	P	1	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13169	13169	T	A	MI.21021	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	833	278	L	Q	cTa/cAa	0,41	0,05	0	probably_damaging	1	neutral	0,28	neutral	4,37	deleterious	-4,56	deleterious	-5,01	high_impact	3,85	neutral	0,68	damaging	0,1	deleterious	4,25	23,9	0,21	0,45	NA	NA	disease	0,81	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,01	high_impact	2,31	0,61	0,8	12,94	6,99	N	0,36	N	0,98	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13169	13169	T	C	MI.21022	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	833	278	L	P	cTa/cCa	0,41	0,05	0	probably_damaging	1	neutral	0,17	neutral	4,37	deleterious	-4,9	deleterious	-6,01	high_impact	3,56	neutral	0,63	damaging	0,09	deleterious	3,99	23,6	0,21	0,45	NA	NA	disease	0,83	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,15	high_impact	2,05	0,64	0,8	12,94	6,99	N	0,37	N	0,99	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13171	13171	T	A	MI.21023	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	835	279	C	S	Tgc/Agc	-3,94	0	0	benign	0,05	neutral	0,62	neutral	4,67	neutral	0,36	deleterious	-8,13	low_impact	1,18	neutral	0,78	neutral	0,87	deleterious	2,4	18,83	0,39	0,5	disease	0,69	disease	0,81	disease	0,64	disease	0,56	1	neutral	0,32	deleterious	0,79	neutral	-6	deleterious	0,79	medium_impact	0,47	medium_impact	0,35	medium_impact	-0,13	0,55	0,8	9,62	13,35	N	0,24	N	0,45	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13171	13171	T	G	MI.21024	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	835	279	C	G	Tgc/Ggc	-3,94	0	0	possibly_damaging	0,54	neutral	0,38	neutral	4,66	neutral	1,35	deleterious	-10,04	low_impact	1,45	neutral	0,7	neutral	0,45	deleterious	3,28	22,8	0,32	0,5	disease	0,71	disease	0,89	disease	0,7	disease	0,75	5	neutral	0,62	neutral	0,42	neutral	-3	deleterious	0,79	medium_impact	-0,81	medium_impact	0,12	medium_impact	0,12	0,46	0,8	9,62	13,35	N	0,33	N	0,79	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13171	13171	T	C	MI.21025	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	835	279	C	R	Tgc/Cgc	-3,94	0	0	probably_damaging	0,91	neutral	0,29	neutral	4,64	neutral	-1,65	deleterious	-10,1	medium_impact	2,92	neutral	0,65	neutral	0,3	deleterious	3,47	23	0,37	0,5	disease	0,86	disease	0,94	disease	0,78	disease	0,86	7	neutral	0,93	neutral	0,19	deleterious	1	deleterious	0,89	low_impact	-1,7	medium_impact	0,02	medium_impact	1,46	0,39	0,8	9,62	13,35	N	0,37	N	0,89	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13172	13172	G	C	MI.21026	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	836	279	C	S	tGc/tCc	5,69	1	0	benign	0,05	neutral	0,62	neutral	4,67	neutral	0,36	deleterious	-8,13	low_impact	1,18	neutral	0,78	neutral	0,87	deleterious	2,06	16,62	0,39	0,5	disease	0,69	disease	0,81	disease	0,64	disease	0,56	1	neutral	0,32	deleterious	0,79	neutral	-6	deleterious	0,79	medium_impact	0,47	medium_impact	0,35	medium_impact	-0,13	0,55	0,8	9,62	13,35	N	0,43	N	0,45	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13172	13172	G	T	MI.21027	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	836	279	C	F	tGc/tTc	5,69	1	0	probably_damaging	0,97	neutral	0,7	neutral	4,68	neutral	1,55	deleterious	-9,32	neutral_impact	0,36	neutral	0,68	neutral	0,37	deleterious	3,87	23,5	0,33	0,5	disease	0,6	disease	0,91	disease	0,7	disease	0,58	1	neutral	0,96	neutral	0,37	neutral	-2	deleterious	0,81	low_impact	-2,18	medium_impact	0,44	medium_impact	-0,87	0,57	0,8	9,62	13,35	N	0,38	N	0,95	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13172	13172	G	A	MI.21028	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	836	279	C	Y	tGc/tAc	5,69	1	0	probably_damaging	0,97	neutral	0,87	neutral	4,67	neutral	0,79	deleterious	-9,32	low_impact	0,83	neutral	0,73	neutral	0,46	deleterious	3,67	23,2	0,33	0,5	disease	0,71	disease	0,91	disease	0,68	disease	0,67	3	neutral	0,96	neutral	0,45	neutral	-2	deleterious	0,83	low_impact	-2,18	medium_impact	0,69	medium_impact	-0,45	0,47	0,8	9,62	13,35	N	0,37	N	0,94	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13173	13173	C	A	MI.21029	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	837	279	C	W	tgC/tgA	4,08	1	0	probably_damaging	0,99	neutral	0,16	neutral	4,66	neutral	1,34	deleterious	-9,38	neutral_impact	0,52	neutral	0,72	neutral	0,57	deleterious	4,58	24,4	0,29	0,45	disease	0,65	disease	0,92	disease	0,63	disease	0,56	1	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,82	low_impact	-2,64	medium_impact	-0,17	medium_impact	-0,73	0,31	0,8	9,62	13,35	N	0,37	N	0,96	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6013	6013	T	A	MI.2103	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	110	37	I	N	aTt/aAt	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-4,07	deleterious	-4,14	high_impact	4,45	damaging	0,57	neutral	0,42	deleterious	4,15	23,8	0,14	0,55	disease	0,94	disease	0,87	disease	0,56	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,01	0,64	0,9	1,75	6,65	P	0,54	P	0,94	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13173	13173	C	G	MI.21030	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	837	279	C	W	tgC/tgG	4,08	1	0	probably_damaging	0,99	neutral	0,16	neutral	4,66	neutral	1,34	deleterious	-9,38	neutral_impact	0,52	neutral	0,72	neutral	0,57	deleterious	4,3	24	0,29	0,45	disease	0,65	disease	0,92	disease	0,63	disease	0,56	1	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,82	low_impact	-2,64	medium_impact	-0,17	medium_impact	-0,73	0,31	0,8	9,62	13,35	N	0,36	N	0,96	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13174	13174	T	G	MI.21031	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	838	280	L	V	Tta/Gta	-2,8	0	0	possibly_damaging	0,9	neutral	0,36	neutral	4,51	neutral	-0,92	neutral	-2,19	low_impact	0,97	neutral	0,68	damaging	0,25	deleterious	3,43	23	0,36	0,5	disease	0,61	neutral	0,43	disease	0,57	disease	0,58	2	neutral	0,9	neutral	0,23	neutral	-3	deleterious	0,72	low_impact	-1,65	medium_impact	0,1	medium_impact	-0,32	0,74	0,85	4,31	8,06	N	0,26	N	0,46	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13174	13174	T	A	MI.21032	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	838	280	L	M	Tta/Ata	-2,8	0	0	possibly_damaging	0,76	neutral	0,29	neutral	4,35	deleterious	-3,25	neutral	-1,57	medium_impact	2,56	neutral	0,64	damaging	0,27	deleterious	3,59	23,2	0,37	0,5	disease	0,85	disease	0,56	disease	0,56	disease	0,61	2	neutral	0,82	neutral	0,27	NA	0	deleterious	0,75	low_impact	-1,22	medium_impact	0,02	medium_impact	1,14	0,73	0,85	4,31	8,06	N	0,3	N	0,65	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13175	13175	T	C	MI.21033	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	839	280	L	S	tTa/tCa	-3,71	0	0	probably_damaging	0,98	neutral	0,43	neutral	4,35	deleterious	-4,25	deleterious	-4,83	medium_impact	2,83	damaging	0,57	damaging	0,12	deleterious	3,77	23,4	0,22	0,45	disease	0,87	disease	0,74	disease	0,65	disease	0,71	4	deleterious	0,98	neutral	0,23	deleterious	1	deleterious	0,81	low_impact	-2,35	medium_impact	0,17	medium_impact	1,38	0,71	0,85	4,31	8,06	N	0,22	N	0,91	polymorphism	0,97	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13175	13175	T	G	MI.21034	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	839	280	L	W	tTa/tGa	-3,71	0	0	probably_damaging	1	neutral	0,11	neutral	4,32	deleterious	-5,08	deleterious	-5,04	high_impact	4,38	neutral	0,62	damaging	0,1	deleterious	3,78	23,4	0,14	0,4	disease	0,59	disease	0,74	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	-0,27	high_impact	2,8	0,52	0,8	4,31	8,06	N	0,36	N	0,95	polymorphism	0,96	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13176	13176	A	C	MI.21035	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	840	280	L	F	ttA/ttC	5,69	0,86	0	probably_damaging	0,98	neutral	0,5	neutral	4,38	neutral	-2,48	deleterious	-3,33	medium_impact	2,53	damaging	0,59	damaging	0,1	deleterious	3,5	23,1	0,44	0,55	disease	0,79	disease	0,69	disease	0,64	disease	0,62	2	neutral	0,98	neutral	0,26	deleterious	1	deleterious	0,78	low_impact	-2,35	medium_impact	0,23	medium_impact	1,11	0,72	0,85	4,31	8,06	N	0,4	N	0,85	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13176	13176	A	T	MI.21036	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	840	280	L	F	ttA/ttT	5,69	0,86	0	probably_damaging	0,98	neutral	0,5	neutral	4,38	neutral	-2,48	deleterious	-3,33	medium_impact	2,53	damaging	0,59	damaging	0,1	deleterious	3,61	23,2	0,44	0,55	disease	0,79	disease	0,69	disease	0,64	disease	0,62	2	neutral	0,98	neutral	0,26	deleterious	1	deleterious	0,78	low_impact	-2,35	medium_impact	0,23	medium_impact	1,11	0,72	0,85	4,31	8,06	N	0,4	N	0,85	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13177	13177	G	T	MI.21037	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	841	281	G	C	Ggc/Tgc	-1,88	0	0	probably_damaging	1	neutral	0,2	neutral	4,43	deleterious	-6,8	deleterious	-8,11	high_impact	4,2	damaging	0,32	damaging	0,14	deleterious	4,19	23,8	0,22	0,45	disease	0,87	disease	0,9	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,1	high_impact	2,63	0,43	0,8	28,86	7,22	P	0,56	P	0,97	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13177	13177	G	A	MI.21038	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	841	281	G	S	Ggc/Agc	-1,88	0	0	probably_damaging	1	neutral	0,46	neutral	4,62	deleterious	-3,09	deleterious	-5,41	medium_impact	2,67	damaging	0,36	damaging	0,23	deleterious	4,21	23,9	0,33	0,5	disease	0,72	disease	0,83	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,19	medium_impact	1,24	0,61	0,8	28,86	7,22	N	0,51	P	1	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13177	13177	G	C	MI.21039	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	841	281	G	R	Ggc/Cgc	-1,88	0	0	probably_damaging	1	neutral	0,34	neutral	4,43	deleterious	-6,34	deleterious	-7,21	high_impact	5,09	damaging	0,36	damaging	0,14	deleterious	3,94	23,5	0,2	0,45	disease	0,94	disease	0,91	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,07	high_impact	3,45	0,58	0,8	28,86	7,22	P	0,69	P	1	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6013	6013	T	G	MI.2104	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	110	37	I	S	aTt/aGt	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,62	neutral	-2,83	deleterious	-3,54	high_impact	5	neutral	0,7	neutral	0,5	deleterious	4,02	23,6	0,16	0,55	disease	0,9	disease	0,88	disease	0,54	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,63	0,9	1,75	6,65	P	0,72	P	0,62	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13178	13178	G	T	MI.21040	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	842	281	G	V	gGc/gTc	8,9	1	0	probably_damaging	1	neutral	0,53	neutral	4,48	deleterious	-4,23	deleterious	-8,11	high_impact	4,54	damaging	0,26	damaging	0,18	deleterious	3,74	23,3	0,22	0,45	disease	0,8	disease	0,87	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,26	high_impact	2,94	0,46	0,8	28,86	7,22	P	0,87	P	0,98	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13178	13178	G	A	MI.21041	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	842	281	G	D	gGc/gAc	8,9	1	0	probably_damaging	1	neutral	0,2	neutral	4,42	deleterious	-7,07	deleterious	-6,31	high_impact	5,09	damaging	0,39	damaging	0,18	deleterious	3,84	23,4	0,15	0,4	disease	0,97	disease	0,89	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,1	high_impact	3,45	0,37	0,8	28,86	7,22	P	0,8	P	0,95	disease_causing	1	0,43	.	.	.	.	.	head/neck tumor	.	.	.	.	.	.	.	.	.
chrM	13178	13178	G	C	MI.21042	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	842	281	G	A	gGc/gCc	8,9	1	0	probably_damaging	1	neutral	0,56	neutral	4,62	neutral	-1,87	deleterious	-5,41	medium_impact	3,32	damaging	0,37	neutral	0,32	deleterious	3,12	22,6	0,33	0,5	disease	0,54	disease	0,67	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,29	medium_impact	1,83	0,64	0,8	28,86	7,22	P	0,74	P	0,79	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13180	13180	G	C	MI.21043	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	844	282	A	P	Gct/Cct	-14,27	0	0	probably_damaging	1	neutral	0,21	neutral	4,48	deleterious	-5,71	deleterious	-4,45	high_impact	4,4	neutral	0,67	damaging	0,09	deleterious	3,87	23,5	0,23	0,45	disease	0,92	disease	0,92	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,09	high_impact	2,82	0,64	0,8	2,65	8,12	N	0,4	N	0,96	disease_causing	0,71	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13180	13180	G	T	MI.21044	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	844	282	A	S	Gct/Tct	-14,27	0	0	probably_damaging	1	neutral	0,48	neutral	4,59	deleterious	-3,1	deleterious	-2,6	low_impact	1,03	neutral	0,71	damaging	0,26	deleterious	3,69	23,3	0,57	0,65	disease	0,53	disease	0,79	neutral	0,44	neutral	0,42	2	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,21	medium_impact	-0,26	0,68	0,85	2,65	8,12	N	0,24	N	0,98	polymorphism	0,77	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13180	13180	G	A	MI.21045	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	844	282	A	T	Gct/Act	-14,27	0	0	probably_damaging	1	neutral	0,51	neutral	4,57	neutral	-2,94	deleterious	-3,53	low_impact	1,61	neutral	0,68	damaging	0,12	deleterious	4,22	23,9	0,58	0,65	disease	0,72	disease	0,82	disease	0,61	disease	0,61	2	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,81	low_impact	-3,6	medium_impact	0,24	medium_impact	0,27	0,65	0,8	2,65	8,12	N	0,19	N	0,94	polymorphism	0,59	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13181	13181	C	A	MI.21046	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	845	282	A	D	gCt/gAt	5	1	0	probably_damaging	1	neutral	0,22	neutral	4,48	deleterious	-6,75	deleterious	-5,32	high_impact	4,4	neutral	0,68	damaging	0,09	deleterious	4,46	24,2	0,21	0,45	disease	0,95	disease	0,93	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,07	high_impact	2,82	0,59	0,8	2,65	8,12	P	0,57	P	0,95	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13181	13181	C	T	MI.21047	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	845	282	A	V	gCt/gTt	5	1	0	probably_damaging	1	neutral	0,57	neutral	4,69	neutral	-1,06	deleterious	-3,59	medium_impact	2,38	neutral	0,66	damaging	0,09	deleterious	4,42	24,2	0,59	0,65	disease	0,62	disease	0,85	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,3	medium_impact	0,97	0,65	0,8	2,65	8,12	N	0,42	N	0,76	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13181	13181	C	G	MI.21048	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	845	282	A	G	gCt/gGt	5	1	0	probably_damaging	1	neutral	0,48	neutral	4,52	neutral	-2,32	deleterious	-3,55	low_impact	1,32	neutral	0,66	damaging	0,15	deleterious	3,95	23,6	0,5	0,6	disease	0,73	disease	0,81	disease	0,54	neutral	0,48	0	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	0,21	medium_impact	0	0,75	0,85	2,65	8,12	N	0,39	N	0,82	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13183	13183	A	G	MI.21049	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	847	283	I	V	Atc/Gtc	-12,66	0	0,05	benign	0,04	neutral	0,41	neutral	4,58	neutral	-0,56	neutral	-0,6	low_impact	0,96	neutral	0,86	neutral	0,77	neutral	1,09	11,14	0,65	0,7	disease	0,55	neutral	0,3	neutral	0,5	disease	0,58	2	neutral	0,56	deleterious	0,69	neutral	-6	neutral	0,15	medium_impact	0,57	medium_impact	0,15	medium_impact	-0,33	0,43	0,8	5,47	9,44	N	0,34	N	0,56	polymorphism	1	0,01	rs879155747	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6014	6014	T	G	MI.2105	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	111	37	I	M	atT/atG	7,53	1	0	probably_damaging	1	neutral	0,12	neutral	2,72	neutral	-0,6	neutral	-1,69	medium_impact	2,85	damaging	0,57	neutral	0,69	deleterious	3,26	22,8	0,3	0,55	neutral	0,42	disease	0,59	neutral	0,28	neutral	0,44	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,72	low_impact	-3,58	medium_impact	-0,29	medium_impact	1,53	0,77	0,9	1,75	6,65	P	0,59	P	0,76	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13183	13183	A	T	MI.21050	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	847	283	I	F	Atc/Ttc	-12,66	0	0,05	possibly_damaging	0,78	neutral	0,66	neutral	4,5	neutral	-1,23	deleterious	-2,82	low_impact	1,1	neutral	0,75	neutral	0,67	deleterious	3,77	23,4	0,39	0,5	disease	0,62	disease	0,72	disease	0,56	disease	0,65	3	neutral	0,74	neutral	0,44	neutral	-3	deleterious	0,69	low_impact	-1,27	medium_impact	0,39	medium_impact	-0,2	0,51	0,8	5,47	9,44	N	0,22	N	0,82	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13183	13183	A	C	MI.21051	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	847	283	I	L	Atc/Ctc	-12,66	0	0,05	benign	0,04	neutral	1	neutral	4,75	neutral	-0,05	neutral	-0,83	neutral_impact	-0,52	neutral	0,77	neutral	0,94	neutral	-0,72	0,06	0,37	0,5	neutral	0,44	neutral	0,13	neutral	0,28	neutral	0,24	5	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,19	medium_impact	0,57	high_impact	1,89	low_impact	-1,68	0,52	0,8	5,47	9,44	N	0,31	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13184	13184	T	G	MI.21052	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	848	283	I	S	aTc/aGc	-0,5	0	0	possibly_damaging	0,69	neutral	0,48	neutral	4,45	deleterious	-3,3	deleterious	-4,17	medium_impact	2,06	neutral	0,74	neutral	0,45	deleterious	4,07	23,7	0,38	0,5	disease	0,89	disease	0,73	disease	0,61	disease	0,76	5	neutral	0,67	neutral	0,4	NA	0	deleterious	0,71	low_impact	-1,08	medium_impact	0,21	medium_impact	0,68	0,39	0,8	5,47	9,44	N	0,23	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13184	13184	T	A	MI.21053	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	848	283	I	N	aTc/aAc	-0,5	0	0	possibly_damaging	0,87	neutral	0,25	neutral	4,42	deleterious	-5,35	deleterious	-5,07	high_impact	3,69	neutral	0,73	neutral	0,4	deleterious	4,31	24	0,31	0,45	disease	0,95	disease	0,81	disease	0,64	disease	0,82	6	neutral	0,91	neutral	0,19	deleterious	1	deleterious	0,81	low_impact	-1,53	medium_impact	-0,03	high_impact	2,17	0,5	0,8	5,47	9,44	N	0,33	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13184	13184	T	C	MI.21054	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	848	283	I	T	aTc/aCc	-0,5	0	0	benign	0,1	neutral	0,43	neutral	4,55	neutral	-2,66	deleterious	-3,17	low_impact	0,97	neutral	0,84	neutral	0,94	deleterious	1,9	15,58	0,57	0,65	disease	0,85	neutral	0,36	neutral	0,45	disease	0,65	3	neutral	0,51	deleterious	0,67	neutral	-6	deleterious	0,58	medium_impact	0,16	medium_impact	0,17	medium_impact	-0,32	0,45	0,8	5,47	9,44	N	0,28	N	0,94	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13185	13185	C	A	MI.21055	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	849	283	I	M	atC/atA	3,63	0,52	0	possibly_damaging	0,87	neutral	0,44	neutral	4,46	deleterious	-3,13	neutral	-1,3	neutral_impact	0,78	neutral	0,81	neutral	0,95	deleterious	2,33	18,35	0,43	0,55	disease	0,8	neutral	0,39	neutral	0,38	disease	0,65	3	neutral	0,87	neutral	0,29	neutral	-3	deleterious	0,69	low_impact	-1,53	medium_impact	0,18	medium_impact	-0,49	0,6	0,8	5,47	9,44	N	0,35	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13185	13185	C	G	MI.21056	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	849	283	I	M	atC/atG	3,63	0,52	0	possibly_damaging	0,87	neutral	0,44	neutral	4,46	deleterious	-3,13	neutral	-1,3	neutral_impact	0,78	neutral	0,81	neutral	0,95	deleterious	1,88	15,47	0,43	0,55	disease	0,8	neutral	0,39	neutral	0,38	disease	0,65	3	neutral	0,87	neutral	0,29	neutral	-3	deleterious	0,69	low_impact	-1,53	medium_impact	0,18	medium_impact	-0,49	0,6	0,8	5,47	9,44	N	0,34	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13186	13186	A	T	MI.21057	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	850	284	T	S	Acc/Tcc	-15,64	0	0	probably_damaging	1	neutral	0,37	neutral	4,78	neutral	-1,46	deleterious	-3,6	medium_impact	2,75	damaging	0,55	damaging	0,2	deleterious	3,31	22,9	0,32	0,5	disease	0,51	disease	0,59	neutral	0,5	neutral	0,44	1	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,11	medium_impact	1,31	0,49	0,8	28,69	7,23	N	0,3	N	0,89	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13186	13186	A	C	MI.21058	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	850	284	T	P	Acc/Ccc	-15,64	0	0	probably_damaging	1	neutral	0,11	neutral	4,43	deleterious	-6,57	deleterious	-5,4	high_impact	5,2	damaging	0,49	damaging	0,05	deleterious	3,47	23	0,19	0,45	disease	0,88	disease	0,88	disease	0,8	disease	0,8	6	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,27	high_impact	3,55	0,36	0,8	28,69	7,23	P	0,56	P	0,97	polymorphism	0,97	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13186	13186	A	G	MI.21059	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	850	284	T	A	Acc/Gcc	-15,64	0	0	probably_damaging	1	neutral	0,54	neutral	4,5	neutral	-2,99	deleterious	-4,5	high_impact	5,2	damaging	0,49	damaging	0,05	deleterious	3,51	23,1	0,33	0,5	disease	0,82	disease	0,64	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,27	high_impact	3,55	0,42	0,8	28,69	7,23	P	0,58	P	0,69	polymorphism	0,99	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6014	6014	T	A	MI.2106	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	111	37	I	M	atT/atA	7,53	1	0	probably_damaging	1	neutral	0,12	neutral	2,72	neutral	-0,6	neutral	-1,69	medium_impact	2,85	damaging	0,57	neutral	0,69	deleterious	3,48	23,1	0,3	0,55	neutral	0,42	disease	0,59	neutral	0,28	neutral	0,44	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,72	low_impact	-3,58	medium_impact	-0,29	medium_impact	1,53	0,77	0,9	1,75	6,65	P	0,61	P	0,76	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13187	13187	C	G	MI.21060	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	851	284	T	S	aCc/aGc	4,31	0,99	0	probably_damaging	1	neutral	0,37	neutral	4,78	neutral	-1,46	deleterious	-3,6	medium_impact	2,75	damaging	0,55	damaging	0,2	deleterious	3,5	23,1	0,32	0,5	disease	0,51	disease	0,59	neutral	0,5	neutral	0,44	1	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,11	medium_impact	1,31	0,49	0,8	28,69	7,23	N	0,47	N	0,89	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13187	13187	C	T	MI.21061	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	851	284	T	I	aCc/aTc	4,31	0,99	0	probably_damaging	1	neutral	0,33	neutral	4,46	deleterious	-5,01	deleterious	-5,4	high_impact	4,85	damaging	0,5	damaging	0,03	deleterious	4	23,6	0,35	0,5	disease	0,95	disease	0,85	disease	0,68	disease	0,8	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,06	high_impact	3,23	0,59	0,8	28,69	7,23	P	0,65	P	0,95	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13187	13187	C	A	MI.21062	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	851	284	T	N	aCc/aAc	4,31	0,99	0	probably_damaging	1	neutral	0,21	neutral	4,48	deleterious	-4,46	deleterious	-4,5	high_impact	5,2	damaging	0,49	damaging	0,03	deleterious	3,69	23,3	0,31	0,45	disease	0,84	disease	0,85	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	-0,09	high_impact	3,55	0,6	0,8	28,69	7,23	P	0,68	P	0,93	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13189	13189	A	G	MI.21063	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	853	285	T	A	Act/Gct	-8,53	0	0	possibly_damaging	0,84	neutral	0,62	neutral	4,72	neutral	2,21	deleterious	-4,46	neutral_impact	-0,43	neutral	0,61	damaging	0,15	deleterious	3,48	23,1	0,6	0,65	neutral	0,4	neutral	0,36	disease	0,57	neutral	0,43	1	neutral	0,82	neutral	0,39	neutral	-3	deleterious	0,68	low_impact	-1,43	medium_impact	0,35	low_impact	-1,6	0,42	0,8	18,08	7	N	0,25	N	0,69	polymorphism	0,83	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13189	13189	A	C	MI.21064	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	853	285	T	P	Act/Cct	-8,53	0	0	probably_damaging	0,99	neutral	0,16	neutral	4,57	deleterious	-3,51	deleterious	-5,37	high_impact	3,54	damaging	0,49	damaging	0,04	deleterious	3,47	23	0,18	0,45	disease	0,91	disease	0,89	disease	0,75	disease	0,75	5	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-2,64	medium_impact	-0,17	high_impact	2,03	0,58	0,8	18,08	7	N	0,3	N	0,97	disease_causing	0,52	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13189	13189	A	T	MI.21065	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	853	285	T	S	Act/Tct	-8,53	0	0	possibly_damaging	0,57	neutral	0,58	neutral	4,63	neutral	-0,44	deleterious	-3,54	neutral_impact	0,29	damaging	0,59	damaging	0,2	deleterious	3,24	22,8	0,55	0,6	disease	0,68	disease	0,63	disease	0,54	neutral	0,46	1	neutral	0,52	deleterious	0,51	neutral	-3	deleterious	0,74	medium_impact	-0,86	medium_impact	0,31	medium_impact	-0,94	0,62	0,8	18,08	7	N	0,19	N	0,89	polymorphism	0,93	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13190	13190	C	T	MI.21066	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	854	285	T	I	aCt/aTt	6,61	1	0	probably_damaging	0,99	neutral	0,38	neutral	4,8	neutral	1,69	deleterious	-5,37	medium_impact	2,21	damaging	0,46	damaging	0,04	deleterious	3,9	23,5	0,55	0,6	neutral	0,45	disease	0,84	disease	0,59	disease	0,68	4	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,74	low_impact	-2,64	medium_impact	0,12	medium_impact	0,82	0,59	0,8	18,08	7	N	0,44	N	0,95	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13190	13190	C	G	MI.21067	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	854	285	T	S	aCt/aGt	6,61	1	0	possibly_damaging	0,57	neutral	0,58	neutral	4,63	neutral	-0,44	deleterious	-3,54	neutral_impact	0,29	damaging	0,59	damaging	0,2	deleterious	3,43	23	0,55	0,6	disease	0,68	disease	0,63	disease	0,54	neutral	0,46	1	neutral	0,52	deleterious	0,51	neutral	-3	deleterious	0,74	medium_impact	-0,86	medium_impact	0,31	medium_impact	-0,94	0,62	0,8	18,08	7	N	0,43	N	0,89	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13190	13190	C	A	MI.21068	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	854	285	T	N	aCt/aAt	6,61	1	0	probably_damaging	0,96	neutral	0,28	neutral	4,58	neutral	-2,93	deleterious	-4,46	medium_impact	3,19	damaging	0,5	damaging	0,04	deleterious	3,57	23,2	0,53	0,6	disease	0,86	disease	0,85	disease	0,65	disease	0,74	5	neutral	0,96	neutral	0,16	deleterious	1	deleterious	0,81	low_impact	-2,06	medium_impact	0,01	medium_impact	1,71	0,8	0,85	18,08	7	P	0,5	N	0,93	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13192	13192	C	A	MI.21069	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	856	286	L	M	Ctg/Atg	-8,07	0	0	benign	0,38	neutral	0,33	neutral	4,04	deleterious	-3,58	neutral	-1,79	medium_impact	2,13	neutral	0,77	neutral	0,68	deleterious	3,76	23,4	0,32	0,5	disease	0,78	neutral	0,46	neutral	0,37	disease	0,63	3	neutral	0,61	deleterious	0,48	neutral	-3	deleterious	0,73	medium_impact	-0,54	medium_impact	0,06	medium_impact	0,74	0,68	0,85	9,95	12,41	N	0,29	N	0,89	polymorphism	0,89	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6015	6015	C	G	MI.2107	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	112	38	R	G	Cga/Gga	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-6,4	deleterious	-4,27	high_impact	4,44	damaging	0,47	damaging	0,08	deleterious	4,03	23,7	0,22	0,55	disease	0,87	disease	0,74	disease	0,73	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3	0,49	0,9	2,73	6,99	N	0,42	N	0,92	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13192	13192	C	G	MI.21070	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	856	286	L	V	Ctg/Gtg	-8,07	0	0	benign	0,12	neutral	0,42	neutral	4,12	neutral	-2,43	deleterious	-2,69	low_impact	1,51	neutral	0,77	neutral	0,66	deleterious	3,41	23	0,31	0,5	disease	0,55	neutral	0,43	neutral	0,37	disease	0,58	2	neutral	0,51	deleterious	0,65	neutral	-6	deleterious	0,71	medium_impact	0,08	medium_impact	0,16	medium_impact	0,18	0,54	0,8	9,95	12,41	N	0,31	N	0,81	polymorphism	0,86	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13193	13193	T	C	MI.21071	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	857	286	L	P	cTg/cCg	-3,94	0	0	probably_damaging	0,96	neutral	0,19	neutral	3,97	deleterious	-7,24	deleterious	-6,29	high_impact	4,55	damaging	0,59	neutral	0,32	deleterious	3,83	23,4	0,18	0,45	disease	0,96	disease	0,86	disease	0,69	disease	0,8	6	neutral	0,98	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-2,06	medium_impact	-0,12	high_impact	2,95	0,68	0,85	9,95	12,41	N	0,39	N	0,99	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13193	13193	T	G	MI.21072	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	857	286	L	R	cTg/cGg	-3,94	0	0	probably_damaging	0,95	neutral	0,26	neutral	3,97	deleterious	-6,86	deleterious	-5,39	high_impact	4,55	neutral	0,62	neutral	0,32	deleterious	4,15	23,8	0,16	0,45	disease	0,94	disease	0,88	disease	0,69	disease	0,79	6	neutral	0,96	neutral	0,16	deleterious	2	deleterious	0,9	low_impact	-1,96	medium_impact	-0,02	high_impact	2,95	0,47	0,8	9,95	12,41	N	0,42	N	1	polymorphism	0,99	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13193	13193	T	A	MI.21073	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	857	286	L	Q	cTg/cAg	-3,94	0	0	probably_damaging	0,96	neutral	0,21	neutral	3,97	deleterious	-6,82	deleterious	-5,39	high_impact	4,55	neutral	0,66	neutral	0,39	deleterious	4,04	23,7	0,2	0,45	disease	0,95	disease	0,81	disease	0,58	disease	0,78	6	neutral	0,98	neutral	0,13	deleterious	2	deleterious	0,83	low_impact	-2,06	medium_impact	-0,09	high_impact	2,95	0,6	0,8	9,95	12,41	N	0,44	N	0,98	polymorphism	0,99	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13195	13195	T	A	MI.21074	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	859	287	F	I	Ttc/Atc	-0,73	0,06	0	probably_damaging	1	neutral	0,45	neutral	4,75	neutral	-0,84	deleterious	-5,39	medium_impact	2,56	neutral	0,61	damaging	0,13	deleterious	4,41	24,1	0,32	0,5	neutral	0,48	disease	0,83	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,18	medium_impact	1,14	0,58	0,8	20,4	7,1	N	0,23	N	0,95	disease_causing	0,93	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13195	13195	T	C	MI.21075	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	859	287	F	L	Ttc/Ctc	-0,73	0,06	0	probably_damaging	1	neutral	0,86	neutral	4,79	neutral	0,06	deleterious	-5,39	low_impact	1,32	damaging	0,58	damaging	0,23	deleterious	4,04	23,7	0,34	0,5	neutral	0,46	disease	0,83	disease	0,62	disease	0,63	3	deleterious	1	neutral	0,43	neutral	-2	deleterious	0,72	low_impact	-3,6	medium_impact	0,67	medium_impact	0	0,38	0,8	20,4	7,1	N	0,23	N	0,92	disease_causing	0,93	0,08	.	.	.	.	.	.	COSM488742	.	.	.	.	.	.	.	.
chrM	13195	13195	T	G	MI.21076	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	859	287	F	V	Ttc/Gtc	-0,73	0,06	0	probably_damaging	1	neutral	0,52	neutral	4,69	neutral	-0,14	deleterious	-6,29	medium_impact	2,36	damaging	0,58	damaging	0,11	deleterious	4,06	23,7	0,33	0,5	disease	0,58	disease	0,86	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,25	medium_impact	0,95	0,38	0,8	20,4	7,1	N	0,2	N	0,95	disease_causing	0,96	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13196	13196	T	G	MI.21077	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	860	287	F	C	tTc/tGc	7,3	1	0	probably_damaging	1	neutral	0,19	neutral	4,5	deleterious	-4,54	deleterious	-7,2	high_impact	3,87	damaging	0,58	damaging	0,11	deleterious	4,11	23,7	0,27	0,45	disease	0,92	disease	0,9	disease	0,62	disease	0,8	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	-0,12	high_impact	2,33	0,28	0,8	20,4	7,1	N	0,48	N	0,99	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13196	13196	T	A	MI.21078	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	860	287	F	Y	tTc/tAc	7,3	1	0	probably_damaging	1	neutral	1	neutral	4,61	neutral	0,37	deleterious	-2,7	low_impact	1,32	damaging	0,52	damaging	0,22	deleterious	4,2	23,9	0,3	0,45	neutral	0,5	disease	0,78	disease	0,59	neutral	0,49	0	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,74	low_impact	-3,6	high_impact	1,89	medium_impact	0	0,53	0,8	20,4	7,1	N	0,5	N	0,88	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13196	13196	T	C	MI.21079	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	860	287	F	S	tTc/tCc	7,3	1	0	probably_damaging	1	neutral	0,46	neutral	4,53	deleterious	-3	deleterious	-7,19	medium_impact	3,38	neutral	0,64	damaging	0,13	deleterious	4,25	23,9	0,3	0,45	disease	0,81	disease	0,89	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,19	medium_impact	1,88	0,34	0,8	20,4	7,1	N	0,48	N	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6015	6015	C	T	MI.2108	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	112	38	R	W	Cga/Tga	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-8,98	deleterious	-4,88	high_impact	5,13	damaging	0,58	damaging	0,05	deleterious	4,96	25,1	0,27	0,55	neutral	0,43	disease	0,88	disease	0,71	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,64	0,77	0,9	2,73	6,99	P	0,52	P	1	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13197	13197	C	A	MI.21080	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	861	287	F	L	ttC/ttA	5,46	1	0	probably_damaging	1	neutral	0,86	neutral	4,79	neutral	0,06	deleterious	-5,39	low_impact	1,32	damaging	0,58	damaging	0,23	deleterious	4,69	24,6	0,34	0,5	neutral	0,46	disease	0,83	disease	0,62	disease	0,63	3	deleterious	1	neutral	0,43	neutral	-2	deleterious	0,72	low_impact	-3,6	medium_impact	0,67	medium_impact	0	0,38	0,8	20,4	7,1	N	0,42	N	0,92	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13197	13197	C	G	MI.21081	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	861	287	F	L	ttC/ttG	5,46	1	0	probably_damaging	1	neutral	0,86	neutral	4,79	neutral	0,06	deleterious	-5,39	low_impact	1,32	damaging	0,58	damaging	0,23	deleterious	4,36	24,1	0,34	0,5	neutral	0,46	disease	0,83	disease	0,62	disease	0,63	3	deleterious	1	neutral	0,43	neutral	-2	deleterious	0,72	low_impact	-3,6	medium_impact	0,67	medium_impact	0	0,38	0,8	20,4	7,1	N	0,42	N	0,92	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13198	13198	G	T	MI.21082	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	862	288	A	S	Gca/Tca	-3,26	0	0	benign	0,36	neutral	0,41	neutral	4,53	deleterious	-3,07	neutral	0,56	low_impact	1,26	neutral	0,74	neutral	0,82	deleterious	3,31	22,9	0,34	0,5	disease	0,63	disease	0,77	neutral	0,45	disease	0,55	1	neutral	0,52	deleterious	0,53	neutral	-6	deleterious	0,58	medium_impact	-0,51	medium_impact	0,15	medium_impact	-0,05	0,64	0,8	15,26	16,68	N	0,33	N	0,58	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13198	13198	G	A	MI.21083	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	862	288	A	T	Gca/Aca	-3,26	0	0	benign	0,01	neutral	0,42	neutral	4,53	neutral	-2,44	neutral	3,7	medium_impact	2,11	neutral	0,76	neutral	0,91	neutral	-0,4	0,39	0,34	0,5	disease	0,58	neutral	0,12	neutral	0,23	neutral	0,35	3	neutral	0,57	deleterious	0,71	neutral	-3	neutral	0,17	medium_impact	1,15	medium_impact	0,16	medium_impact	0,73	0,71	0,85	15,26	16,68	N	0,46	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13198	13198	G	C	MI.21084	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	862	288	A	P	Gca/Cca	-3,26	0	0	possibly_damaging	0,81	neutral	0,2	neutral	4,43	deleterious	-5,37	neutral	-1,23	high_impact	4,71	damaging	0,58	neutral	0,34	deleterious	3,8	23,4	0,19	0,45	disease	0,86	disease	0,93	disease	0,69	disease	0,81	6	neutral	0,89	neutral	0,2	deleterious	1	deleterious	0,87	low_impact	-1,34	medium_impact	-0,1	high_impact	3,1	0,58	0,8	15,26	16,68	P	0,66	P	0,75	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13199	13199	C	A	MI.21085	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	863	288	A	E	gCa/gAa	0,87	0,02	0	possibly_damaging	0,56	neutral	0,27	neutral	4,46	deleterious	-5,14	neutral	-1,23	high_impact	4,16	neutral	0,64	neutral	0,53	deleterious	4,32	24	0,16	0,45	disease	0,74	disease	0,91	disease	0,68	disease	0,76	5	neutral	0,73	neutral	0,36	deleterious	1	deleterious	0,76	medium_impact	-0,85	medium_impact	-0,01	high_impact	2,6	0,59	0,8	15,26	16,68	N	0,42	N	0,77	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13199	13199	C	G	MI.21086	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	863	288	A	G	gCa/gGa	0,87	0,02	0	possibly_damaging	0,44	neutral	0,34	neutral	4,79	neutral	0,94	neutral	-1,97	low_impact	1,57	neutral	0,67	neutral	0,58	deleterious	3,65	23,2	0,39	0,5	neutral	0,37	disease	0,82	disease	0,55	disease	0,72	4	neutral	0,62	neutral	0,45	neutral	-3	deleterious	0,56	medium_impact	-0,65	medium_impact	0,07	medium_impact	0,23	0,7	0,85	15,26	16,68	N	0,37	N	0,49	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13199	13199	C	T	MI.21087	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	863	288	A	V	gCa/gTa	0,87	0,02	0	benign	0,36	neutral	0,51	neutral	4,49	deleterious	-3,15	neutral	-0,31	high_impact	4,71	neutral	0,67	neutral	0,67	deleterious	4,1	23,7	0,39	0,5	disease	0,88	disease	0,78	disease	0,57	disease	0,77	5	neutral	0,41	deleterious	0,58	neutral	-2	deleterious	0,66	medium_impact	-0,51	medium_impact	0,24	high_impact	3,1	0,66	0,8	15,26	16,68	P	0,65	P	0,47	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13201	13201	G	T	MI.21088	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	865	289	A	S	Gca/Tca	-4,63	0	0	benign	0,42	neutral	0,5	neutral	4,93	neutral	1,16	deleterious	-2,69	low_impact	1,18	damaging	0,37	damaging	0,06	deleterious	3,72	23,3	0,41	0,5	disease	0,56	disease	0,88	disease	0,53	disease	0,51	0	neutral	0,45	deleterious	0,54	neutral	-6	deleterious	0,84	medium_impact	-0,61	medium_impact	0,23	medium_impact	-0,13	0,77	0,85	25,21	7,14	N	0,44	N	0,98	disease_causing	0,54	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13201	13201	G	A	MI.21089	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	865	289	A	T	Gca/Aca	-4,63	0	0	probably_damaging	0,94	neutral	0,49	neutral	4,52	neutral	-0,94	deleterious	-3,59	high_impact	3,62	damaging	0,47	damaging	0,01	deleterious	4,22	23,9	0,41	0,5	disease	0,68	disease	0,89	disease	0,57	disease	0,69	4	neutral	0,93	neutral	0,28	deleterious	2	deleterious	0,85	low_impact	-1,88	medium_impact	0,22	high_impact	2,1	0,7	0,85	25,21	7,14	N	0,31	N	0,94	disease_causing	0,73	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6016	6016	G	A	MI.2109	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	113	38	R	Q	cGa/cAa	2,9	0,98	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-4,81	neutral	-2,44	high_impact	4,79	damaging	0,59	damaging	0,05	deleterious	4,29	24	0,41	0,55	disease	0,7	disease	0,84	disease	0,72	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,32	0,83	0,9	2,73	6,99	P	0,66	P	0,99	disease_causing	1	0,4	rs28588369	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13201	13201	G	C	MI.21090	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	865	289	A	P	Gca/Cca	-4,63	0	0	probably_damaging	0,99	neutral	0,23	neutral	4,38	deleterious	-4,14	deleterious	-4,5	high_impact	4,72	damaging	0,47	damaging	0,02	deleterious	3,89	23,5	0,18	0,45	disease	0,93	disease	0,93	disease	0,76	disease	0,84	7	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,91	low_impact	-2,64	medium_impact	-0,06	high_impact	3,11	0,69	0,85	25,21	7,14	P	0,63	P	0,96	disease_causing	0,9	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13202	13202	C	A	MI.21091	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	866	289	A	E	gCa/gAa	5	1	0	probably_damaging	0,97	neutral	0,36	neutral	4,4	deleterious	-3	deleterious	-4,49	high_impact	4,72	damaging	0,51	damaging	0,02	deleterious	4,5	24,3	0,16	0,45	disease	0,78	disease	0,94	disease	0,73	disease	0,83	6	neutral	0,97	neutral	0,2	deleterious	2	deleterious	0,9	low_impact	-2,18	medium_impact	0,1	high_impact	3,11	0,61	0,8	25,21	7,14	P	0,7	P	0,99	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13202	13202	C	G	MI.21092	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	866	289	A	G	gCa/gGa	5	1	0	possibly_damaging	0,9	neutral	0,37	neutral	4,6	neutral	-0,27	deleterious	-3,6	low_impact	1,39	damaging	0,48	damaging	0,06	deleterious	3,92	23,5	0,36	0,5	disease	0,65	disease	0,86	disease	0,6	disease	0,52	0	neutral	0,9	neutral	0,24	neutral	-3	deleterious	0,81	low_impact	-1,65	medium_impact	0,11	medium_impact	0,07	0,72	0,85	25,21	7,14	N	0,45	N	0,82	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13202	13202	C	T	MI.21093	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	866	289	A	V	gCa/gTa	5	1	0	probably_damaging	0,97	neutral	0,54	neutral	4,39	deleterious	-3,6	deleterious	-3,6	high_impact	4,03	damaging	0,45	damaging	0,02	deleterious	4,41	24,1	0,5	0,6	disease	0,77	disease	0,9	disease	0,63	disease	0,7	4	neutral	0,96	neutral	0,29	deleterious	2	deleterious	0,86	low_impact	-2,18	medium_impact	0,27	high_impact	2,48	0,69	0,85	25,21	7,14	P	0,56	P	0,76	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13204	13204	G	C	MI.21094	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	868	290	V	L	Gtc/Ctc	-6,93	0	0,01	benign	0,08	neutral	0,54	neutral	4,93	neutral	1,5	neutral	-0,27	neutral_impact	-1,16	neutral	0,79	neutral	0,91	deleterious	0,44	6,97	0,55	0,6	neutral	0,49	neutral	0,4	neutral	0,29	neutral	0,41	2	neutral	0,39	deleterious	0,73	neutral	-6	neutral	0,17	medium_impact	0,26	medium_impact	0,27	low_impact	-2,26	0,64	0,8	11,61	13,06	N	0,3	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13204	13204	G	T	MI.21095	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	868	290	V	F	Gtc/Ttc	-6,93	0	0,01	possibly_damaging	0,49	neutral	0,16	neutral	4,65	neutral	-0,2	neutral	-2,28	neutral_impact	-0,13	neutral	0,77	neutral	0,74	deleterious	2,25	17,84	0,33	0,5	disease	0,51	disease	0,76	neutral	0,31	disease	0,52	0	neutral	0,82	neutral	0,34	neutral	-3	deleterious	0,53	medium_impact	-0,73	medium_impact	-0,17	low_impact	-1,32	0,51	0,8	11,61	13,06	N	0,29	N	0,45	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13204	13204	G	A	MI.21096	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	868	290	V	I	Gtc/Atc	-6,93	0	0,01	benign	0,01	neutral	0,27	neutral	4,73	neutral	0,08	neutral	0,68	neutral_impact	-0,62	neutral	0,83	neutral	0,97	neutral	-1,05	0,01	0,48	0,55	neutral	0,39	neutral	0,12	neutral	0,22	neutral	0,29	4	neutral	0,73	deleterious	0,63	neutral	-6	neutral	0,12	medium_impact	1,15	medium_impact	-0,01	low_impact	-1,77	0,63	0,8	11,61	13,06	N	0,47	N	0	polymorphism	1	0,01	.	.	.	.	.	.	COSM488743	.	.	.	.	.	.	.	.
chrM	13205	13205	T	G	MI.21097	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	869	290	V	G	gTc/gGc	-0,04	0	0	possibly_damaging	0,72	neutral	0,47	neutral	4,57	deleterious	-3,39	deleterious	-5,54	low_impact	1,42	neutral	0,72	neutral	0,52	deleterious	3,55	23,1	0,29	0,45	disease	0,75	disease	0,66	disease	0,55	disease	0,66	3	neutral	0,7	neutral	0,38	neutral	-3	deleterious	0,66	low_impact	-1,14	medium_impact	0,2	medium_impact	0,09	0,55	0,8	11,61	13,06	N	0,24	N	0,62	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13205	13205	T	A	MI.21098	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	869	290	V	D	gTc/gAc	-0,04	0	0	possibly_damaging	0,8	neutral	0,64	neutral	4,53	deleterious	-5,3	deleterious	-4,98	medium_impact	2,66	neutral	0,68	neutral	0,47	deleterious	4,5	24,3	0,13	0,4	disease	0,83	disease	0,78	disease	0,64	disease	0,79	6	neutral	0,77	neutral	0,42	NA	0	deleterious	0,78	low_impact	-1,32	medium_impact	0,37	medium_impact	1,23	0,54	0,8	11,61	13,06	N	0,25	N	0,71	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13205	13205	T	C	MI.21099	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	869	290	V	A	gTc/gCc	-0,04	0	0	benign	0,25	neutral	0,91	neutral	4,59	neutral	-1,28	deleterious	-2,9	neutral_impact	-0,07	neutral	0,8	neutral	0,95	deleterious	0,58	8,02	0,49	0,55	disease	0,56	neutral	0,21	neutral	0,29	neutral	0,48	0	neutral	0,15	deleterious	0,83	neutral	-6	neutral	0,37	medium_impact	-0,29	medium_impact	0,79	low_impact	-1,27	0,36	0,8	11,61	13,06	N	0,27	N	0,37	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8624	8624	C	G	MI.211	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	98	33	T	S	aCc/aGc	-2,65	0	0	benign	0,07	neutral	1	neutral	4,3	neutral	0,09	neutral	-1,2	neutral_impact	-0,01	neutral	0,93	neutral	0,96	neutral	-0,54	0,18	0,6	0,7	neutral	0,28	neutral	0,17	neutral	0,42	neutral	0,26	5	neutral	0,07	deleterious	0,97	neutral	-6	neutral	0,14	medium_impact	0,31	high_impact	1,98	low_impact	-1,11	0,6	0,9	19,47	19,69	N	0,3	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6016	6016	G	C	MI.2110	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	113	38	R	P	cGa/cCa	2,9	0,98	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-6,94	deleterious	-4,27	high_impact	4,09	damaging	0,48	damaging	0,05	deleterious	4,05	23,7	0,18	0,55	disease	0,9	disease	0,89	disease	0,84	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,68	0,43	0,9	2,73	6,99	P	0,51	P	0,99	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13207	13207	T	G	MI.21100	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	871	291	C	G	Tgc/Ggc	-6,7	0	0	probably_damaging	1	neutral	0,37	neutral	4,74	neutral	0,71	deleterious	-10,79	low_impact	1,76	neutral	0,68	damaging	0,15	deleterious	3,27	22,8	0,47	0,55	disease	0,6	disease	0,94	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,19	neutral	-2	deleterious	0,85	low_impact	-3,6	medium_impact	0,11	medium_impact	0,41	0,42	0,8	27,69	7,21	N	0,26	N	0,79	polymorphism	0,79	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13207	13207	T	A	MI.21101	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	871	291	C	S	Tgc/Agc	-6,7	0	0	probably_damaging	1	neutral	0,44	neutral	4,65	neutral	0,48	deleterious	-8,99	neutral_impact	0,22	neutral	0,66	damaging	0,18	deleterious	3,48	23,1	0,61	0,65	neutral	0,42	disease	0,91	disease	0,64	disease	0,55	1	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,82	low_impact	-3,6	medium_impact	0,18	low_impact	-1	0,54	0,8	27,69	7,21	N	0,25	N	0,45	polymorphism	0,88	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13207	13207	T	C	MI.21102	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	871	291	C	R	Tgc/Cgc	-6,7	0	0	probably_damaging	1	neutral	0,34	neutral	4,6	neutral	-0,75	deleterious	-10,79	medium_impact	2,05	neutral	0,62	damaging	0,12	deleterious	3,46	23	0,53	0,6	disease	0,8	disease	0,96	disease	0,79	disease	0,85	7	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,93	low_impact	-3,6	medium_impact	0,07	medium_impact	0,67	0,26	0,8	27,69	7,21	N	0,3	N	0,89	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13208	13208	G	A	MI.21103	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	872	291	C	Y	tGc/tAc	7,3	1	0	probably_damaging	1	neutral	1	neutral	4,63	neutral	0,08	deleterious	-9,89	medium_impact	3,06	neutral	0,68	damaging	0,1	deleterious	3,61	23,2	0,58	0,65	disease	0,69	disease	0,96	disease	0,73	disease	0,84	7	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,89	low_impact	-3,6	high_impact	1,89	medium_impact	1,59	0,54	0,8	27,69	7,21	N	0,37	N	0,94	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13208	13208	G	T	MI.21104	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	872	291	C	F	tGc/tTc	7,3	1	0	probably_damaging	1	neutral	0,71	neutral	4,63	neutral	0,75	deleterious	-9,89	medium_impact	2,23	neutral	0,64	damaging	0,12	deleterious	3,91	23,5	0,45	0,55	disease	0,63	disease	0,97	disease	0,68	disease	0,8	6	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,89	low_impact	-3,6	medium_impact	0,45	medium_impact	0,83	0,43	0,8	27,69	7,21	N	0,36	N	0,95	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13208	13208	G	C	MI.21105	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	872	291	C	S	tGc/tCc	7,3	1	0	probably_damaging	1	neutral	0,44	neutral	4,65	neutral	0,48	deleterious	-8,99	neutral_impact	0,22	neutral	0,66	damaging	0,18	deleterious	3,21	22,7	0,61	0,65	neutral	0,42	disease	0,91	disease	0,64	disease	0,55	1	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,82	low_impact	-3,6	medium_impact	0,18	low_impact	-1	0,54	0,8	27,69	7,21	N	0,36	N	0,45	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13209	13209	C	G	MI.21106	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	873	291	C	W	tgC/tgG	8,9	1	0	probably_damaging	1	neutral	0,18	neutral	4,58	neutral	-2,77	deleterious	-9,89	medium_impact	3,06	neutral	0,65	damaging	0,13	deleterious	4,29	24	0,35	0,5	disease	0,94	disease	0,96	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,91	low_impact	-3,6	medium_impact	-0,13	medium_impact	1,59	0,3	0,8	27,69	7,21	N	0,47	N	0,96	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13209	13209	C	A	MI.21107	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	873	291	C	W	tgC/tgA	8,9	1	0	probably_damaging	1	neutral	0,18	neutral	4,58	neutral	-2,77	deleterious	-9,89	medium_impact	3,06	neutral	0,65	damaging	0,13	deleterious	4,62	24,5	0,35	0,5	disease	0,94	disease	0,96	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,91	low_impact	-3,6	medium_impact	-0,13	medium_impact	1,59	0,3	0,8	27,69	7,21	N	0,47	N	0,96	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13210	13210	G	A	MI.21108	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	874	292	A	T	Gcc/Acc	-3,49	0	0	probably_damaging	1	neutral	0,49	neutral	4,3	deleterious	-5,24	deleterious	-3,59	high_impact	4,42	damaging	0,51	damaging	0,11	deleterious	4,2	23,9	0,31	0,45	disease	0,78	disease	0,89	disease	0,58	disease	0,68	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,22	high_impact	2,83	0,74	0,85	27,36	7,24	N	0,4	N	0,94	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13210	13210	G	C	MI.21109	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	874	292	A	P	Gcc/Ccc	-3,49	0	0	probably_damaging	1	neutral	0,27	neutral	4,24	deleterious	-7,74	deleterious	-4,5	high_impact	5,11	damaging	0,5	damaging	0,12	deleterious	3,85	23,4	0,19	0,45	disease	0,74	disease	0,94	disease	0,77	disease	0,86	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	-0,01	high_impact	3,47	0,72	0,85	27,36	7,24	P	0,63	P	0,96	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6016	6016	G	T	MI.2111	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	113	38	R	L	cGa/cTa	2,9	0,98	0	probably_damaging	0,99	deleterious	0	neutral	2,62	deleterious	-5,86	deleterious	-4,27	high_impact	4,79	damaging	0,59	damaging	0,05	deleterious	4,14	23,8	0,2	0,55	disease	0,82	disease	0,91	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,64	low_impact	-1,48	high_impact	3,32	0,61	0,9	2,73	6,99	P	0,69	P	0,99	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13210	13210	G	T	MI.21110	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	874	292	A	S	Gcc/Tcc	-3,49	0	0	probably_damaging	1	neutral	0,42	neutral	4,35	deleterious	-4,96	deleterious	-2,7	medium_impact	2,83	damaging	0,54	damaging	0,1	deleterious	3,75	23,3	0,24	0,45	disease	0,69	disease	0,91	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,89	low_impact	-3,6	medium_impact	0,16	medium_impact	1,38	0,65	0,8	27,36	7,24	N	0,23	N	0,98	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13211	13211	C	T	MI.21111	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	875	292	A	V	gCc/gTc	7,07	1	0	probably_damaging	1	neutral	0,56	neutral	4,32	deleterious	-4,89	deleterious	-3,6	high_impact	4,56	damaging	0,48	damaging	0,07	deleterious	4,51	24,3	0,44	0,55	disease	0,83	disease	0,9	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,29	high_impact	2,96	0,77	0,85	27,36	7,24	P	0,58	P	0,76	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13211	13211	C	G	MI.21112	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	875	292	A	G	gCc/gGc	7,07	1	0	probably_damaging	1	neutral	0,35	neutral	4,54	deleterious	-3,68	deleterious	-3,6	medium_impact	2,42	damaging	0,58	damaging	0,16	deleterious	4,02	23,6	0,28	0,45	disease	0,73	disease	0,77	disease	0,61	disease	0,54	1	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,08	medium_impact	1,01	0,7	0,85	27,36	7,24	N	0,48	N	0,82	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13211	13211	C	A	MI.21113	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	875	292	A	D	gCc/gAc	7,07	1	0	probably_damaging	1	neutral	0,22	neutral	4,25	deleterious	-7,93	deleterious	-5,4	high_impact	5,11	damaging	0,54	damaging	0,1	deleterious	4,53	24,3	0,16	0,45	disease	0,96	disease	0,95	disease	0,75	disease	0,84	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,93	low_impact	-3,6	medium_impact	-0,07	high_impact	3,47	0,58	0,8	27,36	7,24	P	0,64	P	0,95	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13213	13213	C	T	MI.21114	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	877	293	L	F	Ctt/Ttt	-10,6	0	0	probably_damaging	0,98	neutral	1	neutral	4,09	deleterious	-3,22	deleterious	-3,43	medium_impact	2,54	neutral	0,7	damaging	0,1	deleterious	4	23,6	0,5	0,6	disease	0,76	disease	0,79	disease	0,66	disease	0,63	3	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,85	low_impact	-2,35	high_impact	1,89	medium_impact	1,12	0,62	0,8	15,26	15,69	N	0,14	N	0,78	polymorphism	0,94	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13213	13213	C	A	MI.21115	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	877	293	L	I	Ctt/Att	-10,6	0	0	possibly_damaging	0,52	neutral	0,45	neutral	4,18	neutral	-1,37	neutral	-1,47	low_impact	0,98	neutral	0,79	neutral	0,9	deleterious	3,02	22,3	0,5	0,6	disease	0,51	neutral	0,48	neutral	0,29	neutral	0,4	2	neutral	0,55	neutral	0,47	neutral	-3	deleterious	0,76	medium_impact	-0,78	medium_impact	0,18	medium_impact	-0,31	0,77	0,85	15,26	15,69	N	0,33	N	0,09	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13213	13213	C	G	MI.21116	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	877	293	L	V	Ctt/Gtt	-10,6	0	0	possibly_damaging	0,76	neutral	0,54	neutral	4,11	neutral	-2,05	neutral	-2,36	low_impact	1,9	neutral	0,75	damaging	0,19	deleterious	3,47	23	0,5	0,6	disease	0,71	disease	0,62	disease	0,51	neutral	0,5	0	neutral	0,73	neutral	0,39	neutral	-3	deleterious	0,81	low_impact	-1,22	medium_impact	0,27	medium_impact	0,53	0,62	0,8	15,26	15,69	N	0,18	N	0,45	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13214	13214	T	G	MI.21117	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	878	293	L	R	cTt/cGt	-0,27	0	0	probably_damaging	1	neutral	0,35	neutral	4,03	deleterious	-5,22	deleterious	-5,31	high_impact	4,54	neutral	0,63	damaging	0,1	deleterious	4,2	23,9	0,2	0,45	disease	0,9	disease	0,92	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,93	low_impact	-3,6	medium_impact	0,08	high_impact	2,94	0,46	0,8	15,26	15,69	N	0,52	P	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13214	13214	T	C	MI.21118	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	878	293	L	P	cTt/cCt	-0,27	0	0	probably_damaging	1	neutral	0,23	neutral	4,02	deleterious	-6,3	deleterious	-6,13	high_impact	4,18	neutral	0,64	damaging	0,1	deleterious	3,87	23,5	0,22	0,45	disease	0,89	disease	0,89	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,93	low_impact	-3,6	medium_impact	-0,06	high_impact	2,62	0,6	0,8	15,26	15,69	N	0,39	N	0,96	polymorphism	0,74	0,29	.	.	.	.	.	.	COSM488744	.	.	.	.	.	.	.	.
chrM	13214	13214	T	A	MI.21119	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	878	293	L	H	cTt/cAt	-0,27	0	0	probably_damaging	1	neutral	0,58	neutral	4,02	deleterious	-6,3	deleterious	-6,13	high_impact	4,54	neutral	0,68	damaging	0,1	deleterious	4,09	23,7	0,25	0,45	disease	0,96	disease	0,85	disease	0,74	disease	0,83	7	deleterious	0,99	neutral	0,29	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,31	high_impact	2,94	0,5	0,8	15,26	15,69	N	0,39	N	0,86	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6018	6018	G	A	MI.2112	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	115	39	A	T	Gcc/Acc	-7,05	0	0	benign	0,06	neutral	0,39	neutral	2,87	deleterious	-5,4	neutral	-0,55	neutral_impact	0,02	neutral	0,61	neutral	0,67	deleterious	1,95	15,93	0,38	0,55	neutral	0,4	neutral	0,17	neutral	0,17	neutral	0,33	4	neutral	0,57	deleterious	0,67	neutral	-6	neutral	0,14	medium_impact	0,37	medium_impact	0,09	low_impact	-1,08	0,66	0,9	12,09	8,96	N	0,5	N	0,2	polymorphism	0,93	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13216	13216	A	C	MI.21120	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	880	294	T	P	Aca/Cca	-11,28	0	0	probably_damaging	1	neutral	0,23	neutral	4,52	neutral	-2,48	deleterious	-5,4	medium_impact	3,07	neutral	0,67	damaging	0,12	deleterious	3,51	23,1	0,19	0,45	disease	0,91	disease	0,9	disease	0,64	disease	0,75	5	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,9	low_impact	-3,6	medium_impact	-0,06	medium_impact	1,6	0,55	0,8	13,43	7,05	N	0,28	N	0,97	polymorphism	0,87	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13216	13216	A	T	MI.21121	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	880	294	T	S	Aca/Tca	-11,28	0	0	probably_damaging	1	neutral	0,46	neutral	4,65	neutral	-0,78	deleterious	-3,6	low_impact	0,98	neutral	0,69	damaging	0,21	deleterious	3,28	22,8	0,48	0,55	disease	0,83	disease	0,77	neutral	0,47	disease	0,62	2	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,83	low_impact	-3,6	medium_impact	0,19	medium_impact	-0,31	0,67	0,85	13,43	7,05	N	0,23	N	0,89	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13216	13216	A	G	MI.21122	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	880	294	T	A	Aca/Gca	-11,28	0	0	probably_damaging	1	neutral	0,59	neutral	4,63	neutral	1,16	deleterious	-4,5	neutral_impact	0,52	neutral	0,66	damaging	0,23	deleterious	3,5	23,1	0,66	0,7	neutral	0,5	disease	0,64	disease	0,58	neutral	0,49	0	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,32	medium_impact	-0,73	0,39	0,8	13,43	7,05	N	0,16	N	0,69	polymorphism	0,97	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13217	13217	C	A	MI.21123	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	881	294	T	K	aCa/aAa	6,61	1	0	probably_damaging	1	neutral	0,37	neutral	4,62	neutral	-1,1	deleterious	-5,4	low_impact	1,59	neutral	0,7	damaging	0,1	deleterious	4,36	24,1	0,32	0,5	disease	0,73	disease	0,93	disease	0,69	disease	0,76	5	deleterious	1	neutral	0,19	neutral	-2	deleterious	0,87	low_impact	-3,6	medium_impact	0,11	medium_impact	0,25	0,71	0,85	13,43	7,05	N	0,43	N	1	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13217	13217	C	T	MI.21124	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	881	294	T	M	aCa/aTa	6,61	1	0	probably_damaging	1	neutral	0,24	neutral	4,52	neutral	-1,56	deleterious	-5,4	medium_impact	2,45	neutral	0,65	damaging	0,19	deleterious	3,98	23,6	0,49	0,55	disease	0,75	disease	0,84	disease	0,51	disease	0,64	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	-0,04	medium_impact	1,04	0,73	0,85	13,43	7,05	N	0,44	N	0,93	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13219	13219	C	A	MI.21125	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	883	295	Q	K	Caa/Aaa	-4,4	0	0	probably_damaging	1	neutral	0,33	neutral	4,11	deleterious	-3,99	deleterious	-3,6	medium_impact	2,94	damaging	0,57	damaging	0,1	deleterious	4,06	23,7	0,46	0,55	disease	0,8	disease	0,94	disease	0,67	disease	0,78	6	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,9	low_impact	-3,6	medium_impact	0,06	medium_impact	1,48	0,7	0,85	31,01	7,27	N	0,22	N	0,96	disease_causing	0,62	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13219	13219	C	G	MI.21126	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	883	295	Q	E	Caa/Gaa	-4,4	0	0	probably_damaging	1	neutral	0,28	neutral	4,15	deleterious	-3,77	deleterious	-2,7	medium_impact	2,19	damaging	0,6	damaging	0,12	deleterious	3,15	22,6	0,52	0,6	disease	0,71	disease	0,85	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,01	medium_impact	0,8	0,64	0,8	31,01	7,27	N	0,22	N	0,92	polymorphism	0,56	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13220	13220	A	G	MI.21127	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	884	295	Q	R	cAa/cGa	7,07	1	0	probably_damaging	1	neutral	0,35	neutral	4,07	deleterious	-4,71	deleterious	-3,6	high_impact	3,54	neutral	0,62	damaging	0,1	deleterious	3,26	22,8	0,51	0,6	disease	0,71	disease	0,93	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,08	high_impact	2,03	0,53	0,8	31,01	7,27	N	0,52	P	0,85	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13220	13220	A	C	MI.21128	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	884	295	Q	P	cAa/cCa	7,07	1	0	probably_damaging	1	neutral	0,21	neutral	4,03	deleterious	-6,85	deleterious	-5,4	high_impact	4,89	damaging	0,5	damaging	0,13	deleterious	3,19	22,7	0,32	0,5	disease	0,78	disease	0,93	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	-0,09	high_impact	3,26	0,57	0,8	31,01	7,27	P	0,66	P	0,95	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13220	13220	A	T	MI.21129	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	884	295	Q	L	cAa/cTa	7,07	1	0	probably_damaging	1	neutral	0,71	neutral	4,08	deleterious	-6,36	deleterious	-6,3	high_impact	4,34	damaging	0,51	damaging	0,09	deleterious	3,62	23,2	0,31	0,45	disease	0,86	disease	0,93	disease	0,68	disease	0,78	6	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,45	high_impact	2,76	0,45	0,8	31,01	7,27	P	0,53	P	0,96	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6018	6018	G	T	MI.2113	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	115	39	A	S	Gcc/Tcc	-7,05	0	0	possibly_damaging	0,63	neutral	0,06	neutral	2,74	deleterious	-4,93	neutral	-0,84	low_impact	1,43	damaging	0,59	neutral	0,6	deleterious	2,29	18,1	0,31	0,55	neutral	0,44	neutral	0,38	neutral	0,28	neutral	0,49	0	neutral	0,94	neutral	0,22	neutral	-3	neutral	0,33	medium_impact	-0,97	medium_impact	-0,47	medium_impact	0,22	0,85	0,9	12,09	8,96	N	0,47	N	0,64	polymorphism	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13221	13221	A	T	MI.21130	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	885	295	Q	H	caA/caT	5,46	1	0,01	probably_damaging	1	neutral	0,57	neutral	4,04	deleterious	-6,19	deleterious	-4,5	medium_impact	3,4	damaging	0,49	damaging	0,2	deleterious	3,56	23,1	0,52	0,6	disease	0,9	disease	0,87	disease	0,74	disease	0,75	5	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,9	low_impact	-3,6	medium_impact	0,3	medium_impact	1,9	0,64	0,8	31,01	7,27	P	0,6	P	0,94	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13221	13221	A	C	MI.21131	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	885	295	Q	H	caA/caC	5,46	1	0,01	probably_damaging	1	neutral	0,57	neutral	4,04	deleterious	-6,19	deleterious	-4,5	medium_impact	3,4	damaging	0,49	damaging	0,2	deleterious	3,42	23	0,52	0,6	disease	0,9	disease	0,87	disease	0,74	disease	0,75	5	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,9	low_impact	-3,6	medium_impact	0,3	medium_impact	1,9	0,64	0,8	31,01	7,27	P	0,58	P	0,94	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13222	13222	A	T	MI.21132	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	886	296	N	Y	Aat/Tat	1,33	1	0	probably_damaging	1	neutral	1	neutral	4,6	neutral	-2,94	deleterious	-7,2	low_impact	1,45	neutral	0,6	damaging	0,1	deleterious	3,62	23,2	0,52	0,6	disease	0,88	disease	0,93	disease	0,61	disease	0,74	5	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,9	low_impact	-3,6	high_impact	1,89	medium_impact	0,12	0,61	0,8	30,51	7,21	N	0,25	N	0,99	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13222	13222	A	G	MI.21133	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	886	296	N	D	Aat/Gat	1,33	1	0	probably_damaging	1	neutral	0,25	neutral	4,57	neutral	-0,58	deleterious	-4,5	medium_impact	2,53	neutral	0,64	damaging	0,1	deleterious	3,76	23,3	0,74	0,75	disease	0,67	disease	0,87	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	-0,03	medium_impact	1,11	0,63	0,8	30,51	7,21	N	0,35	N	0,94	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13222	13222	A	C	MI.21134	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	886	296	N	H	Aat/Cat	1,33	1	0	probably_damaging	1	neutral	0,55	neutral	4,56	neutral	-1,81	deleterious	-4,5	low_impact	1,4	neutral	0,62	damaging	0,19	deleterious	3,05	22,4	0,61	0,65	disease	0,76	disease	0,82	disease	0,56	disease	0,51	0	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,85	low_impact	-3,6	medium_impact	0,28	medium_impact	0,08	0,57	0,8	30,51	7,21	N	0,27	N	0,97	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13223	13223	A	C	MI.21135	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	887	296	N	T	aAt/aCt	8,44	1	0	probably_damaging	1	neutral	0,45	neutral	4,8	neutral	0,57	deleterious	-5,39	low_impact	1,59	damaging	0,6	damaging	0,09	deleterious	3,4	23	0,69	0,75	neutral	0,36	disease	0,87	disease	0,59	disease	0,65	3	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	0,18	medium_impact	0,25	0,59	0,8	30,51	7,21	N	0,36	N	0,94	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13223	13223	A	T	MI.21136	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	887	296	N	I	aAt/aTt	8,44	1	0	probably_damaging	1	neutral	0,41	neutral	4,68	neutral	-2,77	deleterious	-8,1	medium_impact	2,75	neutral	0,6	damaging	0,09	deleterious	3,84	23,4	0,5	0,6	disease	0,74	disease	0,94	disease	0,57	disease	0,74	5	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,15	medium_impact	1,31	0,38	0,8	30,51	7,21	N	0,41	N	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13223	13223	A	G	MI.21137	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	887	296	N	S	aAt/aGt	8,44	1	0	probably_damaging	1	neutral	0,44	neutral	4,69	neutral	-0,73	deleterious	-4,5	medium_impact	2,12	damaging	0,58	damaging	0,11	deleterious	3,04	22,4	0,73	0,75	disease	0,6	disease	0,89	disease	0,58	disease	0,69	4	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,18	medium_impact	0,73	0,34	0,8	30,51	7,21	N	0,42	N	0,82	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13224	13224	T	G	MI.21138	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	888	296	N	K	aaT/aaG	8,44	1	0	probably_damaging	1	neutral	0,35	neutral	4,59	neutral	-0,33	deleterious	-5,4	medium_impact	2,59	neutral	0,61	damaging	0,09	deleterious	4,06	23,7	0,75	0,8	disease	0,6	disease	0,92	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,08	medium_impact	1,16	0,74	0,85	30,51	7,21	N	0,43	N	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13224	13224	T	A	MI.21139	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	888	296	N	K	aaT/aaA	8,44	1	0	probably_damaging	1	neutral	0,35	neutral	4,59	neutral	-0,33	deleterious	-5,4	medium_impact	2,59	neutral	0,61	damaging	0,09	deleterious	4,39	24,1	0,75	0,8	disease	0,6	disease	0,92	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,08	medium_impact	1,16	0,74	0,85	30,51	7,21	N	0,46	N	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6018	6018	G	C	MI.2114	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	115	39	A	P	Gcc/Ccc	-7,05	0	0	probably_damaging	0,99	neutral	0,05	neutral	2,71	deleterious	-6,77	neutral	-1,85	medium_impact	3,13	damaging	0,55	neutral	0,36	deleterious	3,65	23,2	0,1	0,55	disease	0,73	disease	0,8	disease	0,56	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,82	low_impact	-2,64	medium_impact	-0,52	medium_impact	1,79	0,79	0,9	12,09	8,96	N	0,33	N	0,85	polymorphism	0,78	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13225	13225	G	A	MI.21140	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	889	297	D	N	Gac/Aac	-3,49	0	0	probably_damaging	1	neutral	0,34	neutral	4,27	neutral	-2,82	deleterious	-4,5	high_impact	4,02	damaging	0,16	neutral	0,43	deleterious	4,32	24	0,58	0,65	disease	0,59	disease	0,9	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,07	high_impact	2,47	0,57	0,8	27,69	7,23	P	0,92	P	0,98	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13225	13225	G	T	MI.21141	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	889	297	D	Y	Gac/Tac	-3,49	0	0	probably_damaging	1	neutral	1	neutral	4,16	deleterious	-7,43	deleterious	-8,1	high_impact	5,22	damaging	0,37	neutral	0,32	deleterious	3,95	23,6	0,23	0,45	disease	0,96	disease	0,96	disease	0,76	disease	0,82	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,94	low_impact	-3,6	high_impact	1,89	high_impact	3,57	0,34	0,8	27,69	7,23	P	0,62	P	0,99	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13225	13225	G	C	MI.21142	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	889	297	D	H	Gac/Cac	-3,49	0	0	probably_damaging	1	neutral	0,55	neutral	4,18	deleterious	-5,56	deleterious	-6,3	high_impact	4,33	damaging	0,39	neutral	0,31	deleterious	3,64	23,2	0,38	0,5	disease	0,86	disease	0,91	disease	0,77	disease	0,81	6	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,28	high_impact	2,75	0,47	0,8	27,69	7,23	P	0,6	P	0,99	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13226	13226	A	G	MI.21143	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	890	297	D	G	gAc/gGc	8,9	1	0	probably_damaging	1	neutral	0,35	neutral	4,18	deleterious	-5,57	deleterious	-6,3	high_impact	4,25	damaging	0,33	neutral	0,43	deleterious	4,09	23,7	0,32	0,5	disease	0,92	disease	0,94	disease	0,71	disease	0,81	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,08	high_impact	2,68	0,3	0,8	27,69	7,23	P	0,76	P	0,98	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13226	13226	A	C	MI.21144	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	890	297	D	A	gAc/gCc	8,9	1	0	probably_damaging	1	neutral	0,55	neutral	4,22	deleterious	-5,11	deleterious	-7,19	high_impact	5,22	damaging	0,39	neutral	0,44	deleterious	3,72	23,3	0,28	0,45	disease	0,84	disease	0,87	disease	0,73	disease	0,77	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,28	high_impact	3,57	0,43	0,8	27,69	7,23	P	0,81	P	0,94	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13226	13226	A	T	MI.21145	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	890	297	D	V	gAc/gTc	8,9	1	0	probably_damaging	1	neutral	0,51	neutral	4,18	deleterious	-6,53	deleterious	-8,1	high_impact	5,22	damaging	0,29	neutral	0,35	deleterious	3,82	23,4	0,23	0,45	disease	0,94	disease	0,95	disease	0,73	disease	0,81	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	0,24	high_impact	3,57	0,26	0,8	27,69	7,23	P	0,85	P	0,99	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13227	13227	C	A	MI.21146	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	891	297	D	E	gaC/gaA	8,44	1	0	probably_damaging	1	neutral	0,3	neutral	4,25	deleterious	-3,43	deleterious	-3,6	high_impact	3,9	damaging	0,37	neutral	0,36	deleterious	4,27	24	0,5	0,6	disease	0,82	disease	0,88	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,03	high_impact	2,36	0,42	0,8	27,69	7,23	P	0,78	P	0,91	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13227	13227	C	G	MI.21147	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	891	297	D	E	gaC/gaG	8,44	1	0	probably_damaging	1	neutral	0,3	neutral	4,25	deleterious	-3,43	deleterious	-3,6	high_impact	3,9	damaging	0,37	neutral	0,36	deleterious	3,94	23,5	0,5	0,6	disease	0,82	disease	0,88	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,03	high_impact	2,36	0,42	0,8	27,69	7,23	P	0,77	P	0,91	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13228	13228	A	T	MI.21148	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	892	298	I	F	Atc/Ttc	-2,11	0	0	probably_damaging	0,91	neutral	0,71	neutral	4,35	neutral	-2,82	deleterious	-3,52	medium_impact	2,44	damaging	0,54	damaging	0,07	deleterious	3,7	23,3	0,33	0,5	disease	0,79	disease	0,88	disease	0,6	disease	0,72	4	neutral	0,9	neutral	0,4	deleterious	1	deleterious	0,86	low_impact	-1,7	medium_impact	0,45	medium_impact	1,03	0,83	0,85	9,12	15,7	N	0,18	N	0,96	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13228	13228	A	G	MI.21149	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	892	298	I	V	Atc/Gtc	-2,11	0	0	possibly_damaging	0,62	neutral	0,51	neutral	4,46	neutral	-1,35	neutral	-0,88	medium_impact	2,6	damaging	0,55	damaging	0,22	deleterious	2,99	22,2	0,54	0,6	disease	0,52	disease	0,56	neutral	0,46	neutral	0,46	1	neutral	0,6	neutral	0,45	NA	0	deleterious	0,71	medium_impact	-0,95	medium_impact	0,24	medium_impact	1,17	0,67	0,85	9,12	15,7	N	0,31	N	0,74	disease_causing	0,55	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6019	6019	C	A	MI.2115	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	116	39	A	D	gCc/gAc	3,13	1	0	probably_damaging	0,98	deleterious	0,01	neutral	2,71	deleterious	-6,7	neutral	-2,25	medium_impact	3,48	damaging	0,59	neutral	0,37	deleterious	4,34	24,1	0,12	0,55	disease	0,77	disease	0,73	disease	0,54	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-2,35	medium_impact	-0,92	high_impact	2,11	0,65	0,9	12,09	8,96	N	0,47	N	0,89	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13228	13228	A	C	MI.21150	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	892	298	I	L	Atc/Ctc	-2,11	0	0	benign	0,08	neutral	0,67	neutral	4,6	neutral	-0,19	neutral	-1,69	neutral_impact	0,62	damaging	0,5	damaging	0,11	deleterious	3,69	23,3	0,35	0,5	neutral	0,41	disease	0,57	neutral	0,4	neutral	0,43	1	neutral	0,24	deleterious	0,8	neutral	-6	deleterious	0,7	medium_impact	0,26	medium_impact	0,4	medium_impact	-0,64	0,77	0,85	9,12	15,7	N	0,26	N	0,86	disease_causing	0,74	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13229	13229	T	G	MI.21151	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	893	298	I	S	aTc/aGc	5,46	1	0	possibly_damaging	0,9	neutral	0,41	neutral	4,33	deleterious	-4,49	deleterious	-5,3	high_impact	3,98	damaging	0,52	damaging	0,15	deleterious	4,35	24,1	0,26	0,45	disease	0,81	disease	0,92	disease	0,61	disease	0,73	5	neutral	0,9	neutral	0,26	deleterious	1	deleterious	0,89	low_impact	-1,65	medium_impact	0,15	high_impact	2,43	0,54	0,8	9,12	15,7	P	0,53	P	0,96	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13229	13229	T	A	MI.21152	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	893	298	I	N	aTc/aAc	5,46	1	0	probably_damaging	0,98	neutral	0,32	neutral	4,3	deleterious	-5,86	deleterious	-6,2	high_impact	4,54	damaging	0,51	damaging	0,05	deleterious	4,5	24,3	0,29	0,45	disease	0,93	disease	0,9	disease	0,6	disease	0,81	6	neutral	0,98	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-2,35	medium_impact	0,05	high_impact	2,94	0,54	0,8	9,12	15,7	P	0,51	P	0,99	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13229	13229	T	C	MI.21153	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	893	298	I	T	aTc/aCc	5,46	1	0	possibly_damaging	0,9	neutral	0,41	neutral	4,36	deleterious	-3,87	deleterious	-4,42	high_impact	4,19	damaging	0,5	damaging	0,05	deleterious	3,49	23,1	0,42	0,55	disease	0,64	disease	0,83	disease	0,58	disease	0,67	3	neutral	0,9	neutral	0,26	deleterious	1	deleterious	0,84	low_impact	-1,65	medium_impact	0,15	high_impact	2,62	0,63	0,8	9,12	15,7	P	0,53	P	0,96	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13230	13230	C	G	MI.21154	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	894	298	I	M	atC/atG	7,3	1	0	possibly_damaging	0,49	neutral	0,22	neutral	4,41	neutral	-2,34	deleterious	-2,53	low_impact	1,34	damaging	0,52	damaging	0,12	deleterious	3,35	22,9	0,5	0,6	disease	0,68	disease	0,71	neutral	0,43	disease	0,54	1	neutral	0,76	neutral	0,37	neutral	-3	deleterious	0,78	medium_impact	-0,73	medium_impact	-0,07	medium_impact	0,02	0,85	0,9	9,12	15,7	P	0,5	N	0,76	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13230	13230	C	A	MI.21155	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	894	298	I	M	atC/atA	7,3	1	0	possibly_damaging	0,49	neutral	0,22	neutral	4,41	neutral	-2,34	deleterious	-2,53	low_impact	1,34	damaging	0,52	damaging	0,12	deleterious	3,83	23,4	0,5	0,6	disease	0,68	disease	0,71	neutral	0,43	disease	0,54	1	neutral	0,76	neutral	0,37	neutral	-3	deleterious	0,78	medium_impact	-0,73	medium_impact	-0,07	medium_impact	0,02	0,85	0,9	9,12	15,7	P	0,51	P	0,76	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13231	13231	A	C	MI.21156	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	895	299	K	Q	Aaa/Caa	-4,63	0	0	probably_damaging	1	neutral	0,31	neutral	3,2	deleterious	-7,28	deleterious	-3,6	high_impact	5,25	damaging	0,43	damaging	0,18	deleterious	3,51	23,1	0,26	0,45	disease	0,91	disease	0,84	disease	0,62	disease	0,8	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,04	high_impact	3,59	0,51	0,8	22,72	7,09	P	0,61	P	0,82	disease_causing	0,98	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13231	13231	A	G	MI.21157	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	895	299	K	E	Aaa/Gaa	-4,63	0	0	probably_damaging	1	neutral	0,24	neutral	3,18	deleterious	-7,31	deleterious	-3,6	high_impact	5,25	damaging	0,43	damaging	0,18	deleterious	4,09	23,7	0,21	0,45	disease	0,96	disease	0,87	disease	0,72	disease	0,81	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	-0,04	high_impact	3,59	0,51	0,8	22,72	7,09	P	0,65	P	0,84	disease_causing	0,99	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13232	13232	A	T	MI.21158	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	896	299	K	M	aAa/aTa	8,44	1	0	probably_damaging	1	neutral	0,25	neutral	3,16	deleterious	-8,44	deleterious	-5,4	high_impact	5,25	damaging	0,45	damaging	0,18	deleterious	4,03	23,7	0,19	0,45	disease	0,96	disease	0,83	disease	0,69	disease	0,8	6	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,03	high_impact	3,59	0,5	0,8	22,72	7,09	P	0,66	P	0,4	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13232	13232	A	C	MI.21159	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	896	299	K	T	aAa/aCa	8,44	1	0	probably_damaging	1	neutral	0,48	neutral	3,17	deleterious	-8,22	deleterious	-5,39	high_impact	5,25	damaging	0,38	damaging	0,17	deleterious	3,7	23,3	0,2	0,45	disease	0,97	disease	0,84	disease	0,65	disease	0,8	6	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	0,21	high_impact	3,59	0,41	0,8	22,72	7,09	P	0,75	P	0,75	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6019	6019	C	G	MI.2116	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	116	39	A	G	gCc/gGc	3,13	1	0	benign	0,38	deleterious	0,01	neutral	2,72	deleterious	-5,6	neutral	-1,84	low_impact	1,77	damaging	0,6	neutral	0,51	deleterious	2,4	18,81	0,22	0,55	disease	0,66	neutral	0,36	neutral	0,39	disease	0,62	2	deleterious	0,99	neutral	0,32	neutral	-2	neutral	0,32	medium_impact	-0,56	medium_impact	-0,92	medium_impact	0,54	0,77	0,9	12,09	8,96	P	0,5	N	0,56	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13233	13233	A	C	MI.21160	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	897	299	K	N	aaA/aaC	8,44	1	0	probably_damaging	1	neutral	0,31	neutral	3,17	deleterious	-7,78	deleterious	-4,5	high_impact	5,25	damaging	0,35	damaging	0,15	deleterious	3,76	23,3	0,23	0,45	disease	0,97	disease	0,83	disease	0,69	disease	0,81	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,04	high_impact	3,59	0,49	0,8	22,72	7,09	P	0,76	P	0,63	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13233	13233	A	T	MI.21161	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	897	299	K	N	aaA/aaT	8,44	1	0	probably_damaging	1	neutral	0,31	neutral	3,17	deleterious	-7,78	deleterious	-4,5	high_impact	5,25	damaging	0,35	damaging	0,15	deleterious	3,83	23,4	0,23	0,45	disease	0,97	disease	0,83	disease	0,69	disease	0,81	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,04	high_impact	3,59	0,49	0,8	22,72	7,09	P	0,77	P	0,63	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13234	13234	A	G	MI.21162	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	898	300	K	E	Aaa/Gaa	2,71	1	0	probably_damaging	1	neutral	0,34	neutral	4,39	neutral	-1,99	deleterious	-3,6	high_impact	3,67	damaging	0,42	damaging	0,2	deleterious	3,74	23,3	0,31	0,45	disease	0,76	disease	0,85	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,07	high_impact	2,15	0,63	0,8	29,02	7,19	P	0,66	P	0,84	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13234	13234	A	C	MI.21163	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	898	300	K	Q	Aaa/Caa	2,71	1	0	probably_damaging	1	neutral	0,34	neutral	4,35	neutral	-2,45	deleterious	-3,6	high_impact	3,63	damaging	0,43	damaging	0,16	deleterious	3,24	22,8	0,31	0,45	disease	0,81	disease	0,82	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,07	high_impact	2,11	0,72	0,85	29,02	7,19	P	0,6	P	0,82	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13235	13235	A	C	MI.21164	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	899	300	K	T	aAa/aCa	8,44	1	0	probably_damaging	1	neutral	0,45	neutral	4,34	neutral	-2,87	deleterious	-5,4	high_impact	4,61	damaging	0,39	damaging	0,15	deleterious	3,44	23	0,27	0,45	disease	0,79	disease	0,83	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,18	high_impact	3,01	0,46	0,8	29,02	7,19	P	0,73	P	0,75	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13235	13235	A	T	MI.21165	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	899	300	K	M	aAa/aTa	8,44	1	0	probably_damaging	1	neutral	0,23	neutral	4,32	deleterious	-4,55	deleterious	-5,4	high_impact	4,61	damaging	0,43	damaging	0,18	deleterious	3,7	23,3	0,19	0,45	disease	0,6	disease	0,82	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	-0,06	high_impact	3,01	0,52	0,8	29,02	7,19	P	0,68	P	0,4	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13236	13236	A	C	MI.21166	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	900	300	K	N	aaA/aaC	6,84	1	0	probably_damaging	1	neutral	0,34	neutral	4,38	deleterious	-3,18	deleterious	-4,5	high_impact	4,95	damaging	0,32	damaging	0,15	deleterious	3,84	23,4	0,36	0,5	disease	0,84	disease	0,82	disease	0,65	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,07	high_impact	3,32	0,58	0,8	29,02	7,19	P	0,81	P	0,63	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13236	13236	A	T	MI.21167	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	900	300	K	N	aaA/aaT	6,84	1	0	probably_damaging	1	neutral	0,34	neutral	4,38	deleterious	-3,18	deleterious	-4,5	high_impact	4,95	damaging	0,32	damaging	0,15	deleterious	3,9	23,5	0,36	0,5	disease	0,84	disease	0,82	disease	0,65	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,07	high_impact	3,32	0,58	0,8	29,02	7,19	P	0,82	P	0,63	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13237	13237	A	T	MI.21168	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	901	301	I	F	Atc/Ttc	2,02	1	0	probably_damaging	0,97	neutral	0,78	neutral	4,46	neutral	-2,72	deleterious	-3,6	high_impact	4,43	neutral	0,69	neutral	0,41	deleterious	3,65	23,2	0,34	0,5	disease	0,68	disease	0,85	disease	0,62	disease	0,7	4	neutral	0,97	neutral	0,41	deleterious	2	deleterious	0,82	low_impact	-2,18	medium_impact	0,54	high_impact	2,84	0,81	0,85	24,21	7,37	N	0,47	N	0,96	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13237	13237	A	G	MI.21169	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	901	301	I	V	Atc/Gtc	2,02	1	0	benign	0,18	neutral	0,53	neutral	4,67	neutral	0,36	neutral	-0,9	low_impact	0,9	neutral	0,76	neutral	0,7	deleterious	2,96	22,1	0,52	0,6	neutral	0,48	neutral	0,29	disease	0,51	neutral	0,4	2	neutral	0,36	deleterious	0,68	neutral	-6	deleterious	0,67	medium_impact	-0,12	medium_impact	0,26	medium_impact	-0,38	0,74	0,85	24,21	7,37	N	0,4	N	0,74	disease_causing	0,98	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6019	6019	C	T	MI.2117	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	116	39	A	V	gCc/gTc	3,13	1	0	possibly_damaging	0,5	neutral	0,54	neutral	2,83	deleterious	-5,74	neutral	-0,49	low_impact	1,31	neutral	0,61	neutral	0,41	neutral	0,99	10,58	0,31	0,55	neutral	0,26	neutral	0,39	neutral	0,24	neutral	0,46	1	neutral	0,48	deleterious	0,52	neutral	-3	deleterious	0,52	medium_impact	-0,76	medium_impact	0,23	medium_impact	0,11	0,75	0,9	12,09	8,96	N	0,51	P	0,75	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13237	13237	A	C	MI.21170	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	901	301	I	L	Atc/Ctc	2,02	1	0	possibly_damaging	0,61	neutral	0,74	neutral	4,77	neutral	1,21	neutral	-1,8	medium_impact	2,58	neutral	0,7	neutral	0,46	deleterious	3,66	23,2	0,29	0,45	neutral	0,41	disease	0,69	disease	0,56	disease	0,63	3	neutral	0,53	deleterious	0,57	NA	0	deleterious	0,69	medium_impact	-0,93	medium_impact	0,48	medium_impact	1,15	0,78	0,85	24,21	7,37	N	0,38	N	0,86	disease_causing	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13238	13238	T	G	MI.21171	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	902	301	I	S	aTc/aGc	6,61	1	0	probably_damaging	0,96	neutral	0,45	neutral	4,46	deleterious	-3	deleterious	-5,39	high_impact	3,73	neutral	0,71	neutral	0,56	deleterious	4,36	24,1	0,3	0,45	disease	0,71	disease	0,9	disease	0,61	disease	0,71	4	neutral	0,96	neutral	0,25	deleterious	2	deleterious	0,85	low_impact	-2,06	medium_impact	0,18	high_impact	2,2	0,5	0,8	24,21	7,37	P	0,56	P	0,96	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13238	13238	T	C	MI.21172	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	902	301	I	T	aTc/aCc	6,61	1	0	probably_damaging	0,91	neutral	0,44	neutral	4,45	neutral	-2,87	deleterious	-4,5	medium_impact	3,19	neutral	0,7	neutral	0,45	deleterious	3,51	23,1	0,49	0,55	disease	0,72	disease	0,79	disease	0,61	disease	0,66	3	neutral	0,91	neutral	0,27	deleterious	1	deleterious	0,82	low_impact	-1,7	medium_impact	0,18	medium_impact	1,71	0,6	0,8	24,21	7,37	N	0,5	N	0,96	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13238	13238	T	A	MI.21173	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	902	301	I	N	aTc/aAc	6,61	1	0	probably_damaging	0,98	neutral	0,34	neutral	4,41	deleterious	-4,65	deleterious	-6,3	high_impact	4,08	neutral	0,66	neutral	0,49	deleterious	4,58	24,4	0,33	0,5	disease	0,93	disease	0,89	disease	0,63	disease	0,81	6	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-2,35	medium_impact	0,07	high_impact	2,52	0,61	0,8	24,21	7,37	P	0,56	P	0,99	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13239	13239	C	A	MI.21174	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	903	301	I	M	atC/atA	4,54	1	0	probably_damaging	0,97	neutral	0,25	neutral	4,45	neutral	-0,58	deleterious	-2,7	medium_impact	3,46	neutral	0,7	neutral	0,55	deleterious	3,89	23,5	0,42	0,55	disease	0,65	disease	0,73	disease	0,6	disease	0,64	3	neutral	0,98	neutral	0,14	deleterious	1	deleterious	0,75	low_impact	-2,18	medium_impact	-0,03	medium_impact	1,96	0,9	0,95	24,21	7,37	N	0,47	N	0,76	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13239	13239	C	G	MI.21175	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	903	301	I	M	atC/atG	4,54	1	0	probably_damaging	0,97	neutral	0,25	neutral	4,45	neutral	-0,58	deleterious	-2,7	medium_impact	3,46	neutral	0,7	neutral	0,55	deleterious	3,38	23	0,42	0,55	disease	0,65	disease	0,73	disease	0,6	disease	0,64	3	neutral	0,98	neutral	0,14	deleterious	1	deleterious	0,75	low_impact	-2,18	medium_impact	-0,03	medium_impact	1,96	0,9	0,95	24,21	7,37	N	0,47	N	0,76	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13240	13240	G	T	MI.21176	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	904	302	V	L	Gta/Tta	-5,32	0	0	probably_damaging	1	neutral	0,73	neutral	4,93	neutral	3,28	neutral	-1,86	neutral_impact	0,76	neutral	0,77	damaging	0,16	deleterious	3,68	23,3	0,37	0,5	neutral	0,49	disease	0,74	disease	0,58	disease	0,67	3	deleterious	1	neutral	0,37	neutral	-2	deleterious	0,72	low_impact	-3,6	medium_impact	0,47	medium_impact	-0,51	0,7	0,85	2,49	11,16	N	0,2	N	0,59	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13240	13240	G	C	MI.21177	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	904	302	V	L	Gta/Cta	-5,32	0	0	probably_damaging	1	neutral	0,73	neutral	4,93	neutral	3,28	neutral	-1,86	neutral_impact	0,76	neutral	0,77	damaging	0,16	deleterious	3,52	23,1	0,37	0,5	neutral	0,49	disease	0,74	disease	0,58	disease	0,67	3	deleterious	1	neutral	0,37	neutral	-2	deleterious	0,72	low_impact	-3,6	medium_impact	0,47	medium_impact	-0,51	0,7	0,85	2,49	11,16	N	0,2	N	0,59	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13240	13240	G	A	MI.21178	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	904	302	V	M	Gta/Ata	-5,32	0	0	probably_damaging	1	neutral	0,24	neutral	4,54	neutral	-1,67	neutral	-2,28	medium_impact	2,92	neutral	0,72	damaging	0,13	deleterious	3,74	23,3	0,33	0,5	neutral	0,42	disease	0,75	disease	0,51	disease	0,59	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	-0,04	medium_impact	1,46	0,66	0,8	2,49	11,16	N	0,28	N	0,47	polymorphism	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13241	13241	T	A	MI.21179	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	905	302	V	E	gTa/gAa	-0,73	0	0	probably_damaging	1	neutral	0,28	neutral	4,41	deleterious	-4,23	deleterious	-5,4	high_impact	3,61	neutral	0,68	damaging	0,12	deleterious	4,67	24,5	0,11	0,4	disease	0,93	disease	0,91	disease	0,69	disease	0,82	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,01	high_impact	2,1	0,44	0,8	2,49	11,16	N	0,3	N	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6021	6021	G	C	MI.2118	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	118	40	E	Q	Gag/Cag	-7,97	0	0	probably_damaging	1	deleterious	0,01	neutral	2,8	neutral	-1,38	neutral	-1,73	medium_impact	3,29	damaging	0,48	neutral	0,48	deleterious	3,19	22,7	0,42	0,55	neutral	0,31	disease	0,73	neutral	0,4	disease	0,5	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,94	0,75	0,9	2,34	6,73	N	0,48	N	0,66	polymorphism	0,98	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13241	13241	T	G	MI.21180	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	905	302	V	G	gTa/gGa	-0,73	0	0	probably_damaging	1	neutral	0,34	neutral	4,41	deleterious	-3,95	deleterious	-6,3	high_impact	3,61	neutral	0,69	damaging	0,14	deleterious	3,84	23,4	0,18	0,45	disease	0,91	disease	0,84	disease	0,61	disease	0,81	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,07	high_impact	2,1	0,44	0,8	2,49	11,16	N	0,29	N	0,93	polymorphism	0,92	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13241	13241	T	C	MI.21181	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	905	302	V	A	gTa/gCa	-0,73	0	0	probably_damaging	1	neutral	0,54	neutral	4,46	neutral	-1,98	deleterious	-3,6	high_impact	3,61	neutral	0,72	damaging	0,16	deleterious	3,59	23,2	0,22	0,45	disease	0,71	disease	0,61	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,27	high_impact	2,1	0,51	0,8	2,49	11,16	N	0,24	N	0,81	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13243	13243	G	C	MI.21182	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	907	303	A	P	Gcc/Ccc	-11,74	0	0	probably_damaging	1	neutral	0,21	neutral	2,89	deleterious	-10,32	deleterious	-4,51	high_impact	5,24	damaging	0,34	damaging	0,15	deleterious	3,81	23,4	0,13	0,4	disease	0,98	disease	0,89	disease	0,79	disease	0,87	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,09	high_impact	3,58	0,66	0,8	25,37	7,29	P	0,59	P	0,96	disease_causing	0,61	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13243	13243	G	T	MI.21183	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	907	303	A	S	Gcc/Tcc	-11,74	0	0	probably_damaging	1	neutral	0,46	neutral	2,93	deleterious	-6,66	deleterious	-2,7	high_impact	3,71	damaging	0,33	damaging	0,15	deleterious	3,71	23,3	0,18	0,45	disease	0,87	disease	0,86	disease	0,65	disease	0,76	5	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,19	high_impact	2,19	0,74	0,85	25,37	7,29	N	0,45	N	0,98	polymorphism	0,84	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13243	13243	G	A	MI.21184	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	907	303	A	T	Gcc/Acc	-11,74	0	0	probably_damaging	1	neutral	0,47	neutral	2,92	deleterious	-8,49	deleterious	-3,6	high_impact	5,24	damaging	0,33	damaging	0,12	deleterious	4,27	23,9	0,15	0,4	disease	0,92	disease	0,85	disease	0,69	disease	0,8	6	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,2	high_impact	3,58	0,54	0,8	25,37	7,29	P	0,57	P	0,94	polymorphism	0,69	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13244	13244	C	T	MI.21185	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	908	303	A	V	gCc/gTc	8,9	1	0	probably_damaging	1	neutral	0,52	neutral	2,95	deleterious	-8,67	deleterious	-3,61	high_impact	5,24	damaging	0,25	damaging	0,09	deleterious	4,46	24,2	0,2	0,45	disease	0,91	disease	0,85	disease	0,69	disease	0,78	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,25	high_impact	3,58	0,61	0,8	25,37	7,29	P	0,83	P	0,76	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13244	13244	C	A	MI.21186	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	908	303	A	D	gCc/gAc	8,9	1	0	probably_damaging	1	neutral	0,27	neutral	2,88	deleterious	-11,71	deleterious	-5,41	high_impact	5,24	damaging	0,46	damaging	0,12	deleterious	4,67	24,5	0,11	0,4	disease	0,98	disease	0,92	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,01	high_impact	3,58	0,6	0,8	25,37	7,29	P	0,63	P	0,95	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13244	13244	C	G	MI.21187	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	908	303	A	G	gCc/gGc	8,9	1	0	probably_damaging	1	neutral	0,35	neutral	2,99	deleterious	-6,96	deleterious	-3,61	high_impact	5,24	damaging	0,32	damaging	0,15	deleterious	3,99	23,6	0,18	0,45	disease	0,95	disease	0,81	disease	0,62	disease	0,8	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,08	high_impact	3,58	0,75	0,85	25,37	7,29	P	0,78	P	0,82	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13246	13246	T	A	MI.21188	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	910	304	F	I	Ttc/Atc	-7,61	0	0	probably_damaging	1	neutral	0,48	neutral	4,6	neutral	-2,36	deleterious	-5,12	high_impact	4,05	neutral	0,76	neutral	0,63	deleterious	4,45	24,2	0,18	0,45	disease	0,56	disease	0,84	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,21	high_impact	2,5	0,58	0,8	7,3	9,97	N	0,33	N	0,95	polymorphism	0,52	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13246	13246	T	C	MI.21189	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	910	304	F	L	Ttc/Ctc	-7,61	0	0	probably_damaging	1	neutral	0,71	neutral	4,68	neutral	-1,54	deleterious	-5,05	neutral_impact	0,24	neutral	0,74	neutral	0,8	deleterious	4,08	23,7	0,4	0,5	neutral	0,45	disease	0,72	disease	0,66	disease	0,53	1	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	0,45	medium_impact	-0,98	0,73	0,85	7,3	9,97	N	0,25	N	0,92	disease_causing	0,51	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6021	6021	G	A	MI.2119	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	118	40	E	K	Gag/Aag	-7,97	0	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-2,68	neutral	-2,33	high_impact	3,74	damaging	0,41	neutral	0,3	deleterious	4,31	24	0,41	0,55	disease	0,5	disease	0,89	disease	0,62	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,35	0,64	0,9	2,34	6,73	N	0,51	P	0,72	polymorphism	0,9	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13246	13246	T	G	MI.21190	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	910	304	F	V	Ttc/Gtc	-7,61	0	0	probably_damaging	1	neutral	0,52	neutral	4,6	neutral	-2,14	deleterious	-6,03	high_impact	4,05	neutral	0,73	neutral	0,54	deleterious	4,17	23,8	0,24	0,45	disease	0,68	disease	0,88	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,25	high_impact	2,5	0,59	0,8	7,3	9,97	N	0,33	N	0,95	disease_causing	0,67	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13247	13247	T	G	MI.21191	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	911	304	F	C	tTc/tGc	5,69	1	0	probably_damaging	1	neutral	0,19	neutral	4,54	deleterious	-3,52	deleterious	-6,96	high_impact	4,05	neutral	0,73	neutral	0,5	deleterious	4,14	23,8	0,26	0,45	disease	0,91	disease	0,89	disease	0,75	disease	0,82	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,12	high_impact	2,5	0,48	0,8	7,3	9,97	P	0,57	P	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13247	13247	T	A	MI.21192	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	911	304	F	Y	tTc/tAc	5,69	1	0	probably_damaging	1	neutral	1	neutral	5,02	neutral	3,32	deleterious	-2,63	neutral_impact	-0,21	neutral	0,62	neutral	0,68	deleterious	4,24	23,9	0,22	0,45	neutral	0,49	disease	0,54	disease	0,73	disease	0,59	2	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,74	low_impact	-3,6	high_impact	1,89	low_impact	-1,39	0,72	0,85	7,3	9,97	N	0,48	N	0,88	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13247	13247	T	C	MI.21193	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	911	304	F	S	tTc/tCc	5,69	1	0	probably_damaging	1	neutral	0,49	neutral	4,54	neutral	-2,71	deleterious	-7	high_impact	3,7	neutral	0,84	neutral	0,62	deleterious	4,23	23,9	0,22	0,45	disease	0,82	disease	0,88	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,22	high_impact	2,18	0,47	0,8	7,3	9,97	P	0,59	P	0,97	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13248	13248	C	G	MI.21194	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	912	304	F	L	ttC/ttG	5,69	1	0	probably_damaging	1	neutral	0,71	neutral	4,68	neutral	-1,54	deleterious	-5,05	neutral_impact	0,24	neutral	0,74	neutral	0,8	deleterious	4,41	24,1	0,4	0,5	neutral	0,45	disease	0,72	disease	0,66	disease	0,53	1	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	0,45	medium_impact	-0,98	0,73	0,85	7,3	9,97	N	0,45	N	0,92	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13248	13248	C	A	MI.21195	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	912	304	F	L	ttC/ttA	5,69	1	0	probably_damaging	1	neutral	0,71	neutral	4,68	neutral	-1,54	deleterious	-5,05	neutral_impact	0,24	neutral	0,74	neutral	0,8	deleterious	4,66	24,5	0,4	0,5	neutral	0,45	disease	0,72	disease	0,66	disease	0,53	1	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	0,45	medium_impact	-0,98	0,73	0,85	7,3	9,97	N	0,45	N	0,92	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13249	13249	T	A	MI.21196	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	913	305	S	T	Tcc/Acc	-0,73	0,04	0	probably_damaging	1	neutral	0,44	neutral	2,47	deleterious	-7,09	deleterious	-2,7	high_impact	3,67	damaging	0,36	damaging	0,12	deleterious	3,76	23,3	0,2	0,45	disease	0,83	disease	0,73	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,18	high_impact	2,15	0,68	0,85	28,52	7,39	P	0,58	P	0,71	disease_causing	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13249	13249	T	C	MI.21197	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	913	305	S	P	Tcc/Ccc	-0,73	0,04	0	probably_damaging	1	neutral	0,2	neutral	2,45	deleterious	-8,54	deleterious	-4,51	high_impact	4,5	damaging	0,36	damaging	0,19	deleterious	3,95	23,6	0,17	0,45	disease	0,97	disease	0,86	disease	0,84	disease	0,84	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,1	high_impact	2,91	0,62	0,8	28,52	7,39	P	0,66	P	0,98	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13249	13249	T	G	MI.21198	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	913	305	S	A	Tcc/Gcc	-0,73	0,04	0	probably_damaging	1	neutral	0,56	neutral	2,51	deleterious	-6,22	deleterious	-2,7	high_impact	4,5	damaging	0,37	damaging	0,16	deleterious	3,66	23,2	0,22	0,45	disease	0,84	disease	0,63	disease	0,76	disease	0,72	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,29	high_impact	2,91	0,74	0,85	28,52	7,39	P	0,64	P	0,49	disease_causing	0,97	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13250	13250	C	T	MI.21199	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	914	305	S	F	tCc/tTc	7,3	1	0	probably_damaging	1	neutral	0,76	neutral	2,44	deleterious	-9,94	deleterious	-5,41	high_impact	4,85	damaging	0,28	damaging	0,09	deleterious	4,29	24	0,17	0,45	disease	0,93	disease	0,89	disease	0,77	disease	0,84	7	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,51	high_impact	3,23	0,37	0,8	28,52	7,39	P	0,72	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8626	8626	T	C	MI.212	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	100	34	S	P	Tcc/Ccc	-6,12	0	0	probably_damaging	0,99	neutral	0,62	neutral	4,28	neutral	-2,38	neutral	1,89	neutral_impact	-0,82	neutral	0,89	neutral	0,95	neutral	1,74	14,66	0,42	0,65	neutral	0,33	disease	0,65	neutral	0,25	neutral	0,43	1	deleterious	0,99	neutral	0,32	neutral	-2	deleterious	0,72	low_impact	-2,65	medium_impact	0,41	low_impact	-1,8	0,52	0,9	9,73	14,65	N	0,22	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6022	6022	A	C	MI.2120	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	119	40	E	A	gAg/gCg	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,66	deleterious	-3,28	deleterious	-3,6	high_impact	4,37	damaging	0,52	neutral	0,46	deleterious	3,66	23,2	0,2	0,55	disease	0,58	disease	0,75	disease	0,61	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,94	0,62	0,9	2,34	6,73	P	0,57	P	0,71	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13250	13250	C	G	MI.21200	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	914	305	S	C	tCc/tGc	7,3	1	0	probably_damaging	1	neutral	0,19	neutral	2,49	deleterious	-6,66	deleterious	-4,51	high_impact	4,85	damaging	0,34	damaging	0,13	deleterious	3,59	23,2	0,17	0,45	disease	0,97	disease	0,82	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,12	high_impact	3,23	0,61	0,8	28,52	7,39	P	0,76	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13250	13250	C	A	MI.21201	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	914	305	S	Y	tCc/tAc	7,3	1	0	probably_damaging	1	neutral	1	neutral	2,44	deleterious	-10,34	deleterious	-5,41	high_impact	5,2	damaging	0,35	damaging	0,13	deleterious	4,11	23,8	0,14	0,4	disease	0,95	disease	0,88	disease	0,78	disease	0,85	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,9	low_impact	-3,6	high_impact	1,89	high_impact	3,55	0,63	0,8	28,52	7,39	P	0,68	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13252	13252	A	C	MI.21202	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	916	306	T	P	Act/Cct	-20	0	0	probably_damaging	1	neutral	0,21	neutral	4,05	deleterious	-5,63	deleterious	-5,41	high_impact	4,54	damaging	0,48	damaging	0,14	deleterious	3,5	23,1	0,18	0,45	disease	0,73	disease	0,83	disease	0,85	disease	0,77	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,09	high_impact	2,94	0,58	0,8	25,7	7,43	N	0,48	N	0,97	disease_causing	0,61	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13252	13252	A	G	MI.21203	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	916	306	T	A	Act/Gct	-20	0	0	probably_damaging	1	neutral	0,54	neutral	4,11	deleterious	-3,34	deleterious	-4,51	high_impact	4,68	damaging	0,48	damaging	0,13	deleterious	3,5	23,1	0,32	0,5	disease	0,68	disease	0,64	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,27	high_impact	3,07	0,7	0,85	25,7	7,43	N	0,5	N	0,69	polymorphism	0,77	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13252	13252	A	T	MI.21204	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	916	306	T	S	Act/Tct	-20	0	0	probably_damaging	1	neutral	0,46	neutral	4,78	neutral	0,37	deleterious	-3,6	high_impact	4,88	damaging	0,51	damaging	0,14	deleterious	3,36	22,9	0,3	0,45	neutral	0,48	disease	0,75	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,19	high_impact	3,26	0,63	0,8	25,7	7,43	P	0,6	P	0,89	polymorphism	0,91	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13253	13253	C	T	MI.21205	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	917	306	T	I	aCt/aTt	8,44	1	0	probably_damaging	1	neutral	0,41	neutral	4,04	deleterious	-6,36	deleterious	-5,41	high_impact	4,88	damaging	0,44	damaging	0,12	deleterious	3,92	23,5	0,29	0,45	disease	0,9	disease	0,88	disease	0,74	disease	0,8	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,15	high_impact	3,26	0,66	0,8	25,7	7,43	P	0,75	P	0,95	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13253	13253	C	A	MI.21206	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	917	306	T	N	aCt/aAt	8,44	1	0	probably_damaging	1	neutral	0,32	neutral	4,05	deleterious	-5,39	deleterious	-4,51	high_impact	5,24	damaging	0,41	damaging	0,11	deleterious	3,67	23,3	0,3	0,45	disease	0,95	disease	0,81	disease	0,78	disease	0,85	7	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,05	high_impact	3,58	0,72	0,85	25,7	7,43	P	0,78	P	0,93	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13253	13253	C	G	MI.21207	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	917	306	T	S	aCt/aGt	8,44	1	0	probably_damaging	1	neutral	0,46	neutral	4,78	neutral	0,37	deleterious	-3,6	high_impact	4,88	damaging	0,51	damaging	0,14	deleterious	3,56	23,1	0,3	0,45	neutral	0,48	disease	0,75	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,19	high_impact	3,26	0,63	0,8	25,7	7,43	P	0,72	P	0,89	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13255	13255	T	A	MI.21208	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	919	307	S	T	Tca/Aca	-7,38	0	0	probably_damaging	1	neutral	0,41	neutral	4,64	neutral	-0,19	deleterious	-2,7	neutral_impact	0,09	neutral	0,65	damaging	0,18	deleterious	3,82	23,4	0,36	0,5	disease	0,77	disease	0,51	disease	0,73	disease	0,6	2	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,81	low_impact	-3,6	medium_impact	0,15	low_impact	-1,12	0,66	0,8	29,52	7,37	N	0,22	N	0,71	polymorphism	0,89	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13255	13255	T	G	MI.21209	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	919	307	S	A	Tca/Gca	-7,38	0	0	probably_damaging	1	neutral	0,52	neutral	4,65	neutral	1,04	deleterious	-2,7	low_impact	1,23	neutral	0,63	damaging	0,18	deleterious	3,73	23,3	0,39	0,5	disease	0,73	disease	0,57	disease	0,68	disease	0,56	1	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	0,25	medium_impact	-0,08	0,73	0,85	29,52	7,37	N	0,19	N	0,49	polymorphism	0,96	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6022	6022	A	T	MI.2121	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	119	40	E	V	gAg/gTg	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-4,58	deleterious	-4,22	high_impact	5,06	damaging	0,41	neutral	0,39	deleterious	4,2	23,9	0,2	0,55	disease	0,75	disease	0,86	disease	0,63	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,57	0,59	0,9	2,34	6,73	P	0,82	P	0,67	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13255	13255	T	C	MI.21210	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	919	307	S	P	Tca/Cca	-7,38	0	0	probably_damaging	1	neutral	0,2	neutral	4,61	neutral	-2,57	deleterious	-4,51	medium_impact	3,48	neutral	0,66	damaging	0,16	deleterious	3,98	23,6	0,21	0,45	disease	0,92	disease	0,88	disease	0,82	disease	0,86	7	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,91	low_impact	-3,6	medium_impact	-0,1	medium_impact	1,98	0,72	0,85	29,52	7,37	N	0,34	N	0,98	polymorphism	0,57	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13256	13256	C	G	MI.21211	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	920	307	S	W	tCa/tGa	7,3	1	0	probably_damaging	1	neutral	0,19	neutral	4,61	deleterious	-3,29	deleterious	-6,31	medium_impact	3,48	neutral	0,7	damaging	0,14	deleterious	4,37	24,1	0,14	0,4	disease	0,94	disease	0,9	disease	0,77	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,88	low_impact	-3,6	medium_impact	-0,12	medium_impact	1,98	0,5	0,8	29,52	7,37	P	0,53	P	0,99	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13256	13256	C	T	MI.21212	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	920	307	S	L	tCa/tTa	7,3	1	0	probably_damaging	1	neutral	0,67	neutral	4,83	neutral	1,48	deleterious	-5,41	neutral_impact	0,17	neutral	0,66	damaging	0,16	deleterious	4,61	24,4	0,3	0,45	neutral	0,42	disease	0,82	disease	0,72	disease	0,59	2	deleterious	1	neutral	0,34	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	0,4	low_impact	-1,05	0,75	0,85	29,52	7,37	N	0,41	N	0,99	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13258	13258	A	C	MI.21213	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	922	308	S	R	Agt/Cgt	-5,78	0	0	probably_damaging	1	neutral	0,35	neutral	4,34	deleterious	-4,86	deleterious	-4,51	high_impact	5,21	damaging	0,38	damaging	0,13	deleterious	3,87	23,5	0,19	0,45	disease	0,87	disease	0,88	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,08	high_impact	3,56	0,68	0,85	27,86	7,43	P	0,68	P	0,99	polymorphism	0,81	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13258	13258	A	G	MI.21214	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	922	308	S	G	Agt/Ggt	-5,78	0	0	probably_damaging	1	neutral	0,35	neutral	4,42	deleterious	-3,41	deleterious	-3,61	high_impact	4,05	damaging	0,27	damaging	0,17	deleterious	3,59	23,2	0,34	0,5	disease	0,69	disease	0,73	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,08	high_impact	2,5	0,62	0,8	27,86	7,43	P	0,81	P	0,86	polymorphism	0,96	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13258	13258	A	T	MI.21215	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	922	308	S	C	Agt/Tgt	-5,78	0	0	probably_damaging	1	neutral	0,18	neutral	4,33	deleterious	-6,91	deleterious	-4,51	high_impact	4,86	damaging	0,36	damaging	0,13	deleterious	3,47	23	0,23	0,45	disease	0,97	disease	0,8	disease	0,67	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,13	high_impact	3,24	0,49	0,8	27,86	7,43	P	0,61	P	0,99	polymorphism	0,84	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13259	13259	G	C	MI.21216	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	923	308	S	T	aGt/aCt	6,84	1	0	probably_damaging	1	neutral	0,4	neutral	4,4	deleterious	-4,38	deleterious	-2,7	high_impact	4,17	damaging	0,37	damaging	0,13	deleterious	3,42	23	0,25	0,45	disease	0,78	disease	0,69	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,14	high_impact	2,61	0,74	0,85	27,86	7,43	P	0,72	P	0,71	disease_causing	0,99	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13259	13259	G	T	MI.21217	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	923	308	S	I	aGt/aTt	6,84	1	0	probably_damaging	1	neutral	0,4	neutral	4,35	deleterious	-6,04	deleterious	-5,41	high_impact	5,21	damaging	0,33	damaging	0,13	deleterious	4,11	23,7	0,21	0,45	disease	0,87	disease	0,91	disease	0,71	disease	0,8	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,14	high_impact	3,56	0,71	0,85	27,86	7,43	P	0,76	P	0,99	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13259	13259	G	A	MI.21218	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	923	308	S	N	aGt/aAt	6,84	1	0	probably_damaging	1	neutral	0,31	neutral	4,36	deleterious	-4,46	deleterious	-2,7	high_impact	5,21	damaging	0,27	damaging	0,13	deleterious	3,64	23,2	0,46	0,55	disease	0,83	disease	0,76	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,04	high_impact	3,56	0,55	0,8	27,86	7,43	P	0,89	P	0,87	disease_causing	0,99	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13261	13261	C	A	MI.21219	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	925	309	Q	K	Caa/Aaa	-3,03	0	0	probably_damaging	1	neutral	0,32	neutral	4,36	deleterious	-3,87	deleterious	-3,6	high_impact	5,17	damaging	0,44	damaging	0,14	deleterious	3,94	23,5	0,37	0,5	disease	0,81	disease	0,88	disease	0,78	disease	0,78	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,05	high_impact	3,52	0,74	0,85	28,19	7,36	P	0,74	P	0,96	disease_causing	0,82	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6022	6022	A	G	MI.2122	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	119	40	E	G	gAg/gGg	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-3,93	deleterious	-4,22	high_impact	4,71	damaging	0,35	neutral	0,56	deleterious	4,2	23,9	0,28	0,55	disease	0,68	disease	0,74	disease	0,64	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,25	0,56	0,9	2,34	6,73	P	0,84	P	0,67	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13261	13261	C	G	MI.21220	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	925	309	Q	E	Caa/Gaa	-3,03	0	0	probably_damaging	1	neutral	0,28	neutral	4,4	deleterious	-3,65	deleterious	-2,7	high_impact	4,82	damaging	0,49	damaging	0,13	deleterious	3,1	22,5	0,37	0,5	disease	0,78	disease	0,8	disease	0,78	disease	0,75	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,01	high_impact	3,2	0,6	0,8	28,19	7,36	P	0,73	P	0,92	disease_causing	0,68	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13262	13262	A	C	MI.21221	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	926	309	Q	P	cAa/cCa	7,07	1	0	probably_damaging	1	neutral	0,2	neutral	4,3	deleterious	-6,06	deleterious	-5,41	high_impact	5,17	damaging	0,46	damaging	0,13	deleterious	3,38	22,9	0,3	0,45	disease	0,94	disease	0,89	disease	0,81	disease	0,84	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,1	high_impact	3,52	0,63	0,8	28,19	7,36	P	0,73	P	0,95	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13262	13262	A	G	MI.21222	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	926	309	Q	R	cAa/cGa	7,07	1	0	probably_damaging	1	neutral	0,36	neutral	4,33	deleterious	-4,57	deleterious	-3,6	high_impact	4,82	damaging	0,51	damaging	0,11	deleterious	3,5	23,1	0,36	0,5	disease	0,86	disease	0,89	disease	0,77	disease	0,8	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,1	high_impact	3,2	0,6	0,8	28,19	7,36	P	0,74	P	0,85	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13262	13262	A	T	MI.21223	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	926	309	Q	L	cAa/cTa	7,07	1	0	probably_damaging	1	neutral	0,77	neutral	4,31	deleterious	-5,47	deleterious	-6,31	high_impact	5,17	damaging	0,4	damaging	0,12	deleterious	3,84	23,4	0,22	0,45	disease	0,74	disease	0,88	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,52	high_impact	3,52	0,46	0,8	28,19	7,36	P	0,76	P	0,96	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13263	13263	A	T	MI.21224	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	927	309	Q	H	caA/caT	8,44	1	0,03	probably_damaging	1	neutral	0,55	neutral	4,75	neutral	-0,96	deleterious	-4,5	medium_impact	3,02	damaging	0,4	damaging	0,15	deleterious	3,56	23,1	0,48	0,55	disease	0,55	disease	0,83	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,28	medium_impact	1,56	0,77	0,85	28,19	7,36	P	0,73	P	0,94	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13263	13263	A	C	MI.21225	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	927	309	Q	H	caA/caC	8,44	1	0,03	probably_damaging	1	neutral	0,55	neutral	4,75	neutral	-0,96	deleterious	-4,5	medium_impact	3,02	damaging	0,4	damaging	0,15	deleterious	3,42	23	0,48	0,55	disease	0,55	disease	0,83	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,28	medium_impact	1,56	0,77	0,85	28,19	7,36	P	0,71	P	0,94	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13264	13264	C	A	MI.21226	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	928	310	L	M	Cta/Ata	0,64	0,35	0	probably_damaging	1	neutral	0,28	neutral	4,66	neutral	-0,96	neutral	-1,8	high_impact	3,55	damaging	0,37	damaging	0,17	deleterious	3,94	23,5	0,34	0,5	disease	0,59	disease	0,7	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,01	high_impact	2,04	0,79	0,85	26,53	7,36	P	0,59	P	0,89	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13264	13264	C	G	MI.21227	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	928	310	L	V	Cta/Gta	0,64	0,35	0	probably_damaging	1	neutral	0,5	neutral	4,44	neutral	-1,98	deleterious	-2,7	high_impact	3,94	damaging	0,24	damaging	0,14	deleterious	3,42	23	0,45	0,55	disease	0,74	disease	0,76	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,23	high_impact	2,4	0,62	0,8	26,53	7,36	P	0,86	P	0,81	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13265	13265	T	G	MI.21228	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	929	310	L	R	cTa/cGa	-0,04	0,29	0	probably_damaging	1	neutral	0,36	neutral	4,3	deleterious	-5,78	deleterious	-5,41	high_impact	5,17	damaging	0,36	damaging	0,13	deleterious	4,26	23,9	0,18	0,45	disease	0,95	disease	0,92	disease	0,81	disease	0,84	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	0,1	high_impact	3,52	0,54	0,8	26,53	7,36	P	0,72	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13265	13265	T	C	MI.21229	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	929	310	L	P	cTa/cCa	-0,04	0,29	0	probably_damaging	1	neutral	0,2	neutral	4,3	deleterious	-6,22	deleterious	-6,31	high_impact	4,83	damaging	0,29	damaging	0,14	deleterious	4,01	23,6	0,18	0,45	disease	0,96	disease	0,85	disease	0,8	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,1	high_impact	3,21	0,62	0,8	26,53	7,36	P	0,83	P	0,99	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6023	6023	G	C	MI.2123	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	120	40	E	D	gaG/gaC	8,69	1	0,07	probably_damaging	0,99	deleterious	0	neutral	2,64	neutral	-2,54	neutral	-1,82	high_impact	3,86	damaging	0,45	neutral	0,43	deleterious	3,52	23,1	0,42	0,55	disease	0,52	disease	0,76	disease	0,57	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	2,47	0,8	0,9	2,34	6,73	P	0,64	P	0,69	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13265	13265	T	A	MI.21230	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	929	310	L	Q	cTa/cAa	-0,04	0,29	0	probably_damaging	1	neutral	0,37	neutral	4,3	deleterious	-5,96	deleterious	-5,41	high_impact	5,17	damaging	0,33	damaging	0,13	deleterious	4,42	24,2	0,22	0,45	disease	0,95	disease	0,85	disease	0,71	disease	0,83	7	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,11	high_impact	3,52	0,66	0,8	26,53	7,36	P	0,66	P	0,98	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13267	13267	G	C	MI.21231	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	931	311	G	R	Gga/Cga	-3,03	0	0	probably_damaging	1	neutral	0,38	neutral	3,39	deleterious	-11,38	deleterious	-7,21	high_impact	5,2	damaging	0,44	damaging	0,09	deleterious	3,92	23,5	0,06	0,35	disease	0,97	disease	0,92	disease	0,82	disease	0,82	6	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,93	low_impact	-3,6	medium_impact	0,12	high_impact	3,55	0,66	0,8	28,86	7,38	P	0,51	P	1	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13267	13267	G	T	MI.21232	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	931	311	G	W	Gga/Tga	-3,03	0	0	probably_damaging	1	neutral	0,18	neutral	3,38	deleterious	-12,85	deleterious	-7,21	high_impact	5,2	damaging	0,43	damaging	0,09	deleterious	4,43	24,2	0,1	0,4	disease	0,99	disease	0,91	disease	0,78	disease	0,88	8	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,13	high_impact	3,55	0,39	0,8	28,86	7,38	P	0,47	N	1	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13268	13268	G	A	MI.21233	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	932	311	G	E	gGa/gAa	8,9	1	0	probably_damaging	1	neutral	0,31	neutral	3,4	deleterious	-11,6	deleterious	-7,21	high_impact	5,2	damaging	0,39	damaging	0,09	deleterious	3,94	23,5	0,09	0,35	disease	0,96	disease	0,91	disease	0,82	disease	0,85	7	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,04	high_impact	3,55	0,65	0,8	28,86	7,38	P	0,67	P	1	disease_causing	1	0,44	.	.	.	.	.	.	COSM488746	.	.	.	.	.	.	.	.
chrM	13268	13268	G	C	MI.21234	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	932	311	G	A	gGa/gCa	8,9	1	0	probably_damaging	1	neutral	0,56	neutral	3,48	deleterious	-6,91	deleterious	-5,4	high_impact	3,6	damaging	0,36	damaging	0,15	deleterious	3,09	22,5	0,17	0,45	disease	0,86	disease	0,76	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,29	high_impact	2,09	0,61	0,8	28,86	7,38	P	0,69	P	0,79	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13268	13268	G	T	MI.21235	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	932	311	G	V	gGa/gTa	8,9	1	0	probably_damaging	1	neutral	0,54	neutral	3,4	deleterious	-10,23	deleterious	-8,11	high_impact	5,2	damaging	0,33	damaging	0,09	deleterious	3,79	23,4	0,09	0,35	disease	0,94	disease	0,91	disease	0,75	disease	0,84	7	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,27	high_impact	3,55	0,63	0,8	28,86	7,38	P	0,62	P	0,98	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13270	13270	C	T	MI.21236	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	934	312	L	F	Ctc/Ttc	-5,55	0	0	benign	0,38	neutral	0,72	neutral	4,72	neutral	0,08	deleterious	-3,6	low_impact	1,41	damaging	0,51	neutral	0,41	deleterious	4,03	23,7	0,39	0,5	neutral	0,37	disease	0,79	disease	0,61	disease	0,62	2	neutral	0,28	deleterious	0,67	neutral	-6	deleterious	0,76	medium_impact	-0,54	medium_impact	0,46	medium_impact	0,09	0,63	0,8	28,52	7,24	N	0,33	N	0,99	disease_causing	0,5	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13270	13270	C	A	MI.21237	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	934	312	L	I	Ctc/Atc	-5,55	0	0	possibly_damaging	0,9	neutral	0,4	neutral	4,54	neutral	-1,17	neutral	-1,8	medium_impact	2,9	damaging	0,51	neutral	0,48	deleterious	4,13	23,8	0,38	0,5	disease	0,61	disease	0,77	disease	0,67	disease	0,68	4	neutral	0,9	neutral	0,25	NA	0	deleterious	0,8	low_impact	-1,65	medium_impact	0,14	medium_impact	1,45	0,79	0,85	28,52	7,24	N	0,35	N	0,85	polymorphism	0,9	0,03	.	.	.	.	.	.	COSM488747	.	.	.	.	.	.	.	.
chrM	13270	13270	C	G	MI.21238	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	934	312	L	V	Ctc/Gtc	-5,55	0	0	possibly_damaging	0,9	neutral	0,54	neutral	4,53	neutral	-1,84	deleterious	-2,7	medium_impact	2,65	damaging	0,52	neutral	0,34	deleterious	3,46	23	0,39	0,5	disease	0,69	disease	0,73	disease	0,68	disease	0,66	3	neutral	0,88	neutral	0,32	NA	0	deleterious	0,8	low_impact	-1,65	medium_impact	0,27	medium_impact	1,22	0,76	0,85	28,52	7,24	N	0,26	N	0,81	polymorphism	0,83	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13271	13271	T	C	MI.21239	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	935	312	L	P	cTc/cCc	0,18	0,02	0	probably_damaging	1	neutral	0,2	neutral	4,43	deleterious	-5,28	deleterious	-6,31	high_impact	4,64	damaging	0,44	neutral	0,34	deleterious	4	23,6	0,11	0,4	disease	0,95	disease	0,88	disease	0,77	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,1	high_impact	3,04	0,75	0,85	28,52	7,24	P	0,72	P	0,99	polymorphism	0,66	0,32	.	.	.	.	.	.	.	.	.	T13721C	Exercise intolerance(EXIT)	-	+	Reported	2
chrM	6023	6023	G	T	MI.2124	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	120	40	E	D	gaG/gaT	8,69	1	0,07	probably_damaging	0,99	deleterious	0	neutral	2,64	neutral	-2,54	neutral	-1,82	high_impact	3,86	damaging	0,45	neutral	0,43	deleterious	3,68	23,3	0,42	0,55	disease	0,52	disease	0,76	disease	0,57	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	2,47	0,8	0,9	2,34	6,73	P	0,64	P	0,69	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13271	13271	T	A	MI.21240	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	935	312	L	H	cTc/cAc	0,18	0,02	0	probably_damaging	1	neutral	0,53	neutral	4,43	deleterious	-5,24	deleterious	-6,31	high_impact	4,64	damaging	0,53	neutral	0,3	deleterious	4,31	24	0,13	0,4	disease	0,95	disease	0,87	disease	0,74	disease	0,83	7	deleterious	0,99	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,26	high_impact	3,04	0,68	0,85	28,52	7,24	N	0,5	N	0,97	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13271	13271	T	G	MI.21241	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	935	312	L	R	cTc/cGc	0,18	0,02	0	probably_damaging	0,99	neutral	0,34	neutral	4,43	deleterious	-4,69	deleterious	-5,41	high_impact	4,64	damaging	0,51	neutral	0,3	deleterious	4,24	23,9	0,1	0,4	disease	0,93	disease	0,92	disease	0,77	disease	0,85	7	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,91	low_impact	-2,64	medium_impact	0,07	high_impact	3,04	0,61	0,8	28,52	7,24	P	0,59	P	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13273	13273	A	T	MI.21242	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	937	313	M	L	Ata/Tta	-6,7	0	0	probably_damaging	0,98	neutral	0,72	neutral	4,69	neutral	-1,75	deleterious	-2,7	medium_impact	2,9	damaging	0,37	damaging	0,07	deleterious	3,44	23	0,28	0,45	disease	0,5	disease	0,76	disease	0,7	disease	0,69	4	deleterious	0,98	neutral	0,37	deleterious	1	deleterious	0,68	low_impact	-2,35	medium_impact	0,46	medium_impact	1,45	0,51	0,8	28,03	7,14	N	0,42	N	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13273	13273	A	G	MI.21243	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	937	313	M	V	Ata/Gta	-6,7	0	0	probably_damaging	0,99	neutral	0,53	neutral	4,48	neutral	-1,06	deleterious	-3,6	high_impact	4,13	damaging	0,36	damaging	0,08	deleterious	2,83	21,5	0,37	0,5	disease	0,51	disease	0,82	disease	0,7	disease	0,72	4	deleterious	0,99	neutral	0,27	deleterious	2	deleterious	0,72	low_impact	-2,64	medium_impact	0,26	high_impact	2,57	0,57	0,8	28,03	7,14	N	0,43	N	0,95	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13273	13273	A	C	MI.21244	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	937	313	M	L	Ata/Cta	-6,7	0	0	probably_damaging	0,98	neutral	0,72	neutral	4,69	neutral	-1,75	deleterious	-2,7	medium_impact	2,9	damaging	0,37	damaging	0,07	deleterious	3,34	22,9	0,28	0,45	disease	0,5	disease	0,76	disease	0,7	disease	0,69	4	deleterious	0,98	neutral	0,37	deleterious	1	deleterious	0,68	low_impact	-2,35	medium_impact	0,46	medium_impact	1,45	0,51	0,8	28,03	7,14	N	0,42	N	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13274	13274	T	C	MI.21245	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	938	313	M	T	aTa/aCa	8,44	1	0	probably_damaging	1	neutral	0,42	neutral	4,45	deleterious	-4,36	deleterious	-5,41	high_impact	5,1	damaging	0,45	damaging	0,1	deleterious	2,99	22,2	0,23	0,45	disease	0,76	disease	0,86	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,16	high_impact	3,46	0,32	0,8	28,03	7,14	P	0,69	P	0,99	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13274	13274	T	A	MI.21246	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	938	313	M	K	aTa/aAa	8,44	1	0	probably_damaging	1	neutral	0,29	neutral	4,39	deleterious	-5,88	deleterious	-5,41	high_impact	5,1	damaging	0,46	damaging	0,09	deleterious	4	23,6	0,1	0,4	disease	0,93	disease	0,89	disease	0,79	disease	0,85	7	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,02	high_impact	3,46	0,42	0,8	28,03	7,14	P	0,73	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13275	13275	A	T	MI.21247	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	939	313	M	I	atA/atT	7,3	1	0	probably_damaging	0,99	neutral	0,47	neutral	4,54	neutral	-0,42	deleterious	-3,6	medium_impact	2,77	damaging	0,43	damaging	0,13	deleterious	3,51	23,1	0,38	0,5	neutral	0,46	disease	0,83	disease	0,72	disease	0,73	5	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,77	low_impact	-2,64	medium_impact	0,2	medium_impact	1,33	0,68	0,85	28,03	7,14	P	0,69	P	0,94	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13275	13275	A	C	MI.21248	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	939	313	M	I	atA/atC	7,3	1	0	probably_damaging	0,99	neutral	0,47	neutral	4,54	neutral	-0,42	deleterious	-3,6	medium_impact	2,77	damaging	0,43	damaging	0,13	deleterious	3,45	23	0,38	0,5	neutral	0,46	disease	0,83	disease	0,72	disease	0,73	5	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,77	low_impact	-2,64	medium_impact	0,2	medium_impact	1,33	0,68	0,85	28,03	7,14	P	0,68	P	0,94	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13276	13276	A	G	MI.21249	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	940	314	M	V	Ata/Gta	2,48	1	0	benign	0,01	neutral	0,54	neutral	4,57	neutral	0,2	deleterious	-3,07	low_impact	1,16	neutral	0,88	neutral	0,71	neutral	0,9	10,06	0,46	0,55	disease	0,57	disease	0,68	disease	0,64	disease	0,51	0	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,22	medium_impact	1,15	medium_impact	0,27	medium_impact	-0,14	0,74	0,85	7,3	13,65	N	0,37	N	0,95	disease_causing	0,96	0,08	rs2853502	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6024	6024	C	G	MI.2125	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	121	41	L	V	Ctg/Gtg	0,59	0,05	0	probably_damaging	0,98	deleterious	0	neutral	2,37	deleterious	-5,01	neutral	-1,81	high_impact	5,13	damaging	0,44	damaging	0,08	deleterious	3,23	22,8	0,35	0,55	disease	0,72	disease	0,67	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,35	low_impact	-1,48	high_impact	3,64	0,75	0,9	2,53	7	P	0,61	P	0,66	disease_causing	0,57	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13276	13276	A	C	MI.21250	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	940	314	M	L	Ata/Cta	2,48	1	0	benign	0,12	neutral	0,74	neutral	4,65	neutral	1,02	neutral	-2,34	medium_impact	3,04	neutral	0,66	neutral	0,56	neutral	1,48	13,19	0,44	0,55	neutral	0,41	disease	0,72	disease	0,62	disease	0,6	2	neutral	0,15	deleterious	0,81	neutral	-3	neutral	0,23	medium_impact	0,08	medium_impact	0,48	medium_impact	1,57	0,7	0,85	7,3	13,65	N	0,39	N	0,98	disease_causing	0,95	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13276	13276	A	T	MI.21251	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	940	314	M	L	Ata/Tta	2,48	1	0	benign	0,12	neutral	0,74	neutral	4,65	neutral	1,02	neutral	-2,34	medium_impact	3,04	neutral	0,66	neutral	0,56	neutral	1,55	13,56	0,44	0,55	neutral	0,41	disease	0,72	disease	0,62	disease	0,6	2	neutral	0,15	deleterious	0,81	neutral	-3	neutral	0,23	medium_impact	0,08	medium_impact	0,48	medium_impact	1,57	0,7	0,85	7,3	13,65	N	0,4	N	0,98	disease_causing	0,95	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13277	13277	T	C	MI.21252	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	941	314	M	T	aTa/aCa	5,46	1	0	benign	0,04	neutral	0,43	neutral	4,47	neutral	-0,75	deleterious	-4,67	medium_impact	2,08	neutral	0,71	neutral	0,57	neutral	1,23	11,89	0,35	0,5	disease	0,74	disease	0,82	disease	0,64	disease	0,59	2	neutral	0,53	deleterious	0,7	neutral	-3	deleterious	0,45	medium_impact	0,57	medium_impact	0,17	medium_impact	0,7	0,48	0,8	7,3	13,65	N	0,48	N	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13277	13277	T	A	MI.21253	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	941	314	M	K	aTa/aAa	5,46	1	0	possibly_damaging	0,64	neutral	0,33	neutral	4,42	deleterious	-4,16	deleterious	-5,01	high_impact	4,61	neutral	0,63	neutral	0,36	deleterious	2,67	20,6	0,11	0,4	disease	0,91	disease	0,88	disease	0,75	disease	0,82	6	neutral	0,71	neutral	0,35	deleterious	1	deleterious	0,58	medium_impact	-0,98	medium_impact	0,06	high_impact	3,01	0,55	0,8	7,3	13,65	P	0,63	P	1	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13278	13278	A	C	MI.21254	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	942	314	M	I	atA/atC	7,3	1	0,02	benign	0,25	neutral	0,52	neutral	4,64	neutral	-0,11	deleterious	-3,04	low_impact	1,84	neutral	0,78	neutral	0,95	deleterious	0,39	6,56	0,39	0,5	disease	0,54	disease	0,76	disease	0,62	disease	0,55	1	neutral	0,38	deleterious	0,64	neutral	-6	neutral	0,27	medium_impact	-0,29	medium_impact	0,25	medium_impact	0,48	0,81	0,85	7,3	13,65	N	0,5	N	0,94	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13278	13278	A	T	MI.21255	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	942	314	M	I	atA/atT	7,3	1	0,02	benign	0,25	neutral	0,52	neutral	4,64	neutral	-0,11	deleterious	-3,04	low_impact	1,84	neutral	0,78	neutral	0,95	deleterious	0,63	8,36	0,39	0,5	disease	0,54	disease	0,76	disease	0,62	disease	0,55	1	neutral	0,38	deleterious	0,64	neutral	-6	neutral	0,27	medium_impact	-0,29	medium_impact	0,25	medium_impact	0,48	0,81	0,85	7,3	13,65	N	0,5	N	0,94	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13279	13279	G	T	MI.21256	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	943	315	V	F	Gtt/Ttt	0,64	0,99	0	probably_damaging	0,94	neutral	0,7	neutral	4,57	neutral	-1,49	deleterious	-4,43	low_impact	1,27	neutral	0,67	neutral	0,42	deleterious	3,78	23,4	0,29	0,45	disease	0,65	disease	0,85	disease	0,62	disease	0,56	1	neutral	0,93	neutral	0,38	neutral	-2	deleterious	0,77	low_impact	-1,88	medium_impact	0,44	medium_impact	-0,04	0,73	0,85	5,97	7,55	N	0,26	N	0,96	disease_causing	0,98	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13279	13279	G	A	MI.21257	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	943	315	V	I	Gtt/Att	0,64	0,99	0	benign	0,12	neutral	0,4	neutral	4,65	neutral	-0,32	neutral	-0,9	medium_impact	2,15	neutral	0,67	neutral	0,55	deleterious	3,29	22,8	0,4	0,5	disease	0,52	disease	0,62	neutral	0,49	neutral	0,46	1	neutral	0,53	deleterious	0,64	neutral	-3	deleterious	0,52	medium_impact	0,08	medium_impact	0,14	medium_impact	0,76	0,79	0,85	5,97	7,55	N	0,43	N	0,11	disease_causing	0,63	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13279	13279	G	C	MI.21258	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	943	315	V	L	Gtt/Ctt	0,64	0,99	0	possibly_damaging	0,52	neutral	0,65	neutral	4,67	neutral	0,93	deleterious	-2,65	low_impact	1,22	neutral	0,68	neutral	0,62	deleterious	1,96	15,97	0,35	0,5	neutral	0,34	disease	0,71	disease	0,53	disease	0,51	0	neutral	0,43	deleterious	0,57	neutral	-3	deleterious	0,45	medium_impact	-0,78	medium_impact	0,38	medium_impact	-0,09	0,69	0,85	5,97	7,55	N	0,3	N	0,69	disease_causing	0,85	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13280	13280	T	C	MI.21259	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	944	315	V	A	gTt/gCt	5	1	0	benign	0,12	neutral	0,51	neutral	4,65	neutral	-0,61	deleterious	-3,49	low_impact	1,28	neutral	0,7	neutral	0,59	neutral	1,66	14,2	0,34	0,5	disease	0,69	disease	0,63	disease	0,53	disease	0,52	0	neutral	0,4	deleterious	0,7	neutral	-6	neutral	0,24	medium_impact	0,08	medium_impact	0,24	medium_impact	-0,03	0,38	0,8	5,97	7,55	N	0,45	N	0,75	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6024	6024	C	A	MI.2126	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	121	41	L	M	Ctg/Atg	0,59	0,05	0	probably_damaging	1	neutral	0,06	neutral	2,32	deleterious	-5,74	neutral	-1,22	high_impact	3,75	damaging	0,54	damaging	0,14	deleterious	3,65	23,2	0,3	0,55	disease	0,77	disease	0,69	disease	0,54	disease	0,58	2	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,81	low_impact	-3,58	medium_impact	-0,47	high_impact	2,36	0,82	0,9	2,53	7	N	0,38	N	0,59	disease_causing	0,51	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13280	13280	T	A	MI.21260	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	944	315	V	D	gTt/gAt	5	1	0	probably_damaging	0,96	neutral	0,21	neutral	4,49	deleterious	-5,77	deleterious	-6,16	high_impact	4,08	neutral	0,7	neutral	0,4	deleterious	4,47	24,2	0,09	0,4	disease	0,96	disease	0,89	disease	0,71	disease	0,83	7	neutral	0,97	neutral	0,13	deleterious	2	deleterious	0,8	low_impact	-2,06	medium_impact	-0,09	high_impact	2,52	0,59	0,8	5,97	7,55	N	0,51	P	0,97	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13280	13280	T	G	MI.21261	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	944	315	V	G	gTt/gGt	5	1	0	possibly_damaging	0,83	neutral	0,33	neutral	4,67	deleterious	-3,52	deleterious	-6,17	medium_impact	2,84	neutral	0,66	neutral	0,5	deleterious	2,25	17,87	0,14	0,4	disease	0,76	disease	0,79	disease	0,61	disease	0,67	3	neutral	0,85	neutral	0,25	NA	0	deleterious	0,58	low_impact	-1,4	medium_impact	0,06	medium_impact	1,39	0,56	0,8	5,97	7,55	N	0,47	N	0,91	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13282	13282	A	T	MI.21262	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	946	316	T	S	Aca/Tca	-14,04	0	0	probably_damaging	1	neutral	0,46	neutral	4,65	neutral	-0,5	deleterious	-3,6	neutral_impact	0,38	damaging	0,58	damaging	0,11	deleterious	3,28	22,8	0,57	0,65	disease	0,63	disease	0,59	disease	0,51	neutral	0,49	0	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,19	medium_impact	-0,86	0,69	0,85	14,59	7,01	N	0,23	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13282	13282	A	G	MI.21263	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	946	316	T	A	Aca/Gca	-14,04	0	0	probably_damaging	1	neutral	0,56	neutral	4,73	neutral	2,53	deleterious	-4,51	neutral_impact	-0,66	damaging	0,54	damaging	0,25	deleterious	3,43	23	0,57	0,65	neutral	0,36	neutral	0,25	neutral	0,46	neutral	0,43	1	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	0,29	low_impact	-1,81	0,49	0,8	14,59	7,01	N	0,32	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13282	13282	A	C	MI.21264	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	946	316	T	P	Aca/Cca	-14,04	0	0	probably_damaging	1	neutral	0,2	neutral	4,57	neutral	-1,85	deleterious	-5,41	high_impact	3,62	damaging	0,5	damaging	0,05	deleterious	3,51	23,1	0,16	0,45	disease	0,81	disease	0,85	disease	0,73	disease	0,77	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,1	high_impact	2,1	0,62	0,8	14,59	7,01	N	0,29	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13283	13283	C	T	MI.21265	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	947	316	T	M	aCa/aTa	1,33	0,43	0	probably_damaging	1	neutral	0,32	neutral	4,64	neutral	-1,16	deleterious	-5,41	low_impact	1,47	damaging	0,6	damaging	0,08	deleterious	4	23,6	0,25	0,45	disease	0,66	disease	0,69	disease	0,63	disease	0,56	1	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,05	medium_impact	0,14	0,77	0,85	14,59	7,01	N	0,21	N	0,93	disease_causing	0,95	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13283	13283	C	A	MI.21266	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	947	316	T	K	aCa/aAa	1,33	0,43	0	probably_damaging	1	neutral	0,31	neutral	4,58	neutral	-2,37	deleterious	-5,41	high_impact	3,62	damaging	0,55	damaging	0,04	deleterious	4,41	24,1	0,17	0,45	disease	0,78	disease	0,86	disease	0,73	disease	0,77	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,04	high_impact	2,1	0,7	0,85	14,59	7,01	N	0,31	N	1	disease_causing	0,97	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13285	13285	A	T	MI.21267	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	949	317	I	F	Atc/Ttc	-12,89	0	0	probably_damaging	0,97	neutral	0,71	neutral	4,55	neutral	-1,4	deleterious	-3,18	medium_impact	2,72	neutral	0,72	neutral	0,38	deleterious	3,93	23,5	0,32	0,5	disease	0,63	disease	0,82	disease	0,68	disease	0,69	4	neutral	0,97	neutral	0,37	deleterious	1	deleterious	0,8	low_impact	-2,18	medium_impact	0,45	medium_impact	1,28	0,86	0,9	13,93	13,22	N	0,19	N	0,82	polymorphism	0,78	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13285	13285	A	G	MI.21268	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	949	317	I	V	Atc/Gtc	-12,89	0	0	benign	0,18	neutral	0,53	neutral	4,62	neutral	-0,41	neutral	-0,8	low_impact	1,08	neutral	0,84	neutral	0,82	deleterious	1,95	15,93	0,53	0,6	disease	0,53	neutral	0,44	neutral	0,46	neutral	0,39	2	neutral	0,36	deleterious	0,68	neutral	-6	deleterious	0,67	medium_impact	-0,12	medium_impact	0,26	medium_impact	-0,22	0,74	0,85	13,93	13,22	N	0,29	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13285	13285	A	C	MI.21269	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	949	317	I	L	Atc/Ctc	-12,89	0	0	possibly_damaging	0,73	neutral	0,69	neutral	4,89	neutral	0,9	neutral	-1,01	neutral_impact	0,42	neutral	0,78	neutral	0,91	deleterious	2,53	19,65	0,37	0,5	neutral	0,34	disease	0,53	neutral	0,45	neutral	0,43	1	neutral	0,67	deleterious	0,48	neutral	-3	deleterious	0,66	low_impact	-1,16	medium_impact	0,42	medium_impact	-0,82	0,83	0,85	13,93	13,22	N	0,25	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6025	6025	T	A	MI.2127	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	122	41	L	Q	cTg/cAg	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,34	deleterious	-7,76	deleterious	-3,68	high_impact	5,13	damaging	0,49	damaging	0,08	deleterious	3,99	23,6	0,16	0,55	disease	0,94	disease	0,87	disease	0,64	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,64	0,75	0,9	2,53	7	P	0,56	P	0,82	polymorphism	0,86	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13286	13286	T	C	MI.21270	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	950	317	I	T	aTc/aCc	1,1	0,46	0	probably_damaging	0,91	neutral	0,45	neutral	4,51	deleterious	-3,14	deleterious	-4	medium_impact	3,36	neutral	0,73	neutral	0,4	deleterious	3,48	23,1	0,42	0,55	disease	0,82	disease	0,78	disease	0,67	disease	0,73	5	neutral	0,91	neutral	0,27	deleterious	1	deleterious	0,82	low_impact	-1,7	medium_impact	0,18	medium_impact	1,87	0,71	0,85	13,93	13,22	N	0,26	N	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13286	13286	T	A	MI.21271	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	950	317	I	N	aTc/aAc	1,1	0,46	0	probably_damaging	0,98	neutral	0,36	neutral	4,47	deleterious	-4,89	deleterious	-5,82	high_impact	3,78	neutral	0,7	neutral	0,41	deleterious	4,55	24,3	0,25	0,45	disease	0,93	disease	0,84	disease	0,69	disease	0,81	6	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,84	low_impact	-2,35	medium_impact	0,1	high_impact	2,25	0,74	0,85	13,93	13,22	N	0,34	N	0,93	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13286	13286	T	G	MI.21272	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	950	317	I	S	aTc/aGc	1,1	0,46	0	probably_damaging	0,97	neutral	0,48	neutral	4,52	deleterious	-3,63	deleterious	-4,92	high_impact	3,63	neutral	0,74	neutral	0,44	deleterious	4,31	24	0,25	0,45	disease	0,85	disease	0,85	disease	0,67	disease	0,77	5	neutral	0,97	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-2,18	medium_impact	0,21	high_impact	2,11	0,68	0,85	13,93	13,22	N	0,3	N	0,9	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13287	13287	C	A	MI.21273	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	951	317	I	M	atC/atA	7,3	0,98	0	probably_damaging	0,98	neutral	0,24	neutral	4,55	neutral	-2,58	neutral	-1,97	medium_impact	2,74	neutral	0,77	neutral	0,62	deleterious	3,83	23,4	0,39	0,5	disease	0,79	disease	0,65	disease	0,59	disease	0,62	2	deleterious	0,98	neutral	0,13	deleterious	1	deleterious	0,76	low_impact	-2,35	medium_impact	-0,04	medium_impact	1,3	0,84	0,9	13,93	13,22	P	0,51	P	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13287	13287	C	G	MI.21274	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	951	317	I	M	atC/atG	7,3	0,98	0	probably_damaging	0,98	neutral	0,24	neutral	4,55	neutral	-2,58	neutral	-1,97	medium_impact	2,74	neutral	0,77	neutral	0,62	deleterious	3,33	22,9	0,39	0,5	disease	0,79	disease	0,65	disease	0,59	disease	0,62	2	deleterious	0,98	neutral	0,13	deleterious	1	deleterious	0,76	low_impact	-2,35	medium_impact	-0,04	medium_impact	1,3	0,84	0,9	13,93	13,22	P	0,51	P	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13288	13288	G	A	MI.21275	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	952	318	G	S	Ggc/Agc	-5,09	0	0	probably_damaging	1	neutral	0,45	neutral	4,76	deleterious	-3,51	deleterious	-5,41	medium_impact	2,62	damaging	0,32	damaging	0,03	deleterious	4,17	23,8	0,26	0,45	neutral	0,49	disease	0,85	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,18	medium_impact	1,19	0,68	0,85	28,36	7,14	N	0,45	N	1	disease_causing	0,55	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13288	13288	G	T	MI.21276	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	952	318	G	C	Ggc/Tgc	-5,09	0	0	probably_damaging	1	neutral	0,18	neutral	4,54	deleterious	-6,55	deleterious	-8,11	high_impact	3,77	damaging	0,28	damaging	0,02	deleterious	4,11	23,7	0,14	0,4	disease	0,91	disease	0,92	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,13	high_impact	2,24	0,56	0,8	28,36	7,14	P	0,54	P	0,97	disease_causing	0,84	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13288	13288	G	C	MI.21277	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	952	318	G	R	Ggc/Cgc	-5,09	0	0	probably_damaging	1	neutral	0,38	neutral	4,55	deleterious	-6,24	deleterious	-7,21	high_impact	5,05	damaging	0,33	damaging	0,02	deleterious	3,89	23,5	0,1	0,4	disease	0,91	disease	0,94	disease	0,83	disease	0,87	7	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,93	low_impact	-3,6	medium_impact	0,12	high_impact	3,41	0,59	0,8	28,36	7,14	P	0,56	P	1	disease_causing	0,73	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13289	13289	G	C	MI.21278	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	953	318	G	A	gGc/gCc	8,9	1	0	probably_damaging	1	neutral	0,55	neutral	4,66	neutral	-2,13	deleterious	-5,41	medium_impact	3,21	damaging	0,36	damaging	0,03	deleterious	3,18	22,7	0,39	0,5	disease	0,57	disease	0,8	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,28	medium_impact	1,73	0,65	0,8	28,36	7,14	P	0,62	P	0,79	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13289	13289	G	A	MI.21279	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	953	318	G	D	gGc/gAc	8,9	1	0	probably_damaging	1	neutral	0,24	neutral	4,54	deleterious	-6,56	deleterious	-6,31	high_impact	4,71	damaging	0,26	damaging	0,02	deleterious	3,82	23,4	0,11	0,4	disease	0,95	disease	0,92	disease	0,82	disease	0,84	7	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,04	high_impact	3,1	0,35	0,8	28,36	7,14	P	0,84	P	0,95	disease_causing	1	0,43	rs28683136	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6025	6025	T	C	MI.2128	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	122	41	L	P	cTg/cCg	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,29	deleterious	-8,2	deleterious	-4,29	high_impact	4,79	damaging	0,39	damaging	0,07	deleterious	3,79	23,4	0,18	0,55	disease	0,95	disease	0,87	disease	0,75	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,32	0,56	0,9	2,53	7	P	0,57	P	0,83	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13289	13289	G	T	MI.21280	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	953	318	G	V	gGc/gTc	8,9	1	0	probably_damaging	1	neutral	0,53	neutral	4,58	deleterious	-4,18	deleterious	-8,11	high_impact	4,08	damaging	0,3	damaging	0,02	deleterious	3,8	23,4	0,15	0,4	disease	0,73	disease	0,93	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,26	high_impact	2,52	0,48	0,8	28,36	7,14	P	0,61	P	0,98	disease_causing	1	0,23	rs28683136	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13291	13291	A	T	MI.21281	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	955	319	I	F	Atc/Ttc	-5,55	0	0	probably_damaging	1	neutral	0,71	neutral	4,49	neutral	-1,53	deleterious	-3,44	low_impact	1,56	neutral	0,64	damaging	0,11	deleterious	3,86	23,5	0,49	0,55	disease	0,8	disease	0,73	disease	0,64	disease	0,75	5	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,8	low_impact	-3,6	medium_impact	0,45	medium_impact	0,22	0,84	0,9	15,42	14,58	N	0,15	N	0,82	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13291	13291	A	G	MI.21282	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	955	319	I	V	Atc/Gtc	-5,55	0	0	probably_damaging	1	neutral	0,52	neutral	4,6	neutral	0,73	neutral	-0,86	neutral_impact	0,72	neutral	0,76	damaging	0,22	deleterious	3,1	22,5	0,73	0,75	neutral	0,41	neutral	0,36	disease	0,59	neutral	0,49	0	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,64	low_impact	-3,6	medium_impact	0,25	medium_impact	-0,55	0,65	0,8	15,42	14,58	N	0,23	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13291	13291	A	C	MI.21283	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	955	319	I	L	Atc/Ctc	-5,55	0	0	probably_damaging	1	neutral	0,7	neutral	4,73	neutral	1,13	neutral	-1,58	neutral_impact	-0,88	neutral	0,75	neutral	0,89	neutral	1,1	11,21	0,4	0,5	neutral	0,36	neutral	0,15	neutral	0,25	neutral	0,26	5	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,61	low_impact	-3,6	medium_impact	0,44	low_impact	-2,01	0,8	0,85	15,42	14,58	N	0,29	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13292	13292	T	G	MI.21284	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	956	319	I	S	aTc/aGc	1,56	0,78	0	probably_damaging	1	neutral	0,44	neutral	4,48	neutral	-1,61	deleterious	-5,21	medium_impact	2,14	neutral	0,64	damaging	0,11	deleterious	4,32	24	0,35	0,5	disease	0,55	disease	0,73	disease	0,61	disease	0,71	4	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,18	medium_impact	0,75	0,65	0,8	15,42	14,58	N	0,22	N	0,94	polymorphism	0,96	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13292	13292	T	C	MI.21285	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	956	319	I	T	aTc/aCc	1,56	0,78	0	probably_damaging	1	neutral	0,41	neutral	4,51	neutral	-1,18	deleterious	-4,34	low_impact	1,9	neutral	0,64	damaging	0,17	deleterious	3,45	23	0,51	0,6	neutral	0,4	disease	0,58	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,72	low_impact	-3,6	medium_impact	0,15	medium_impact	0,53	0,74	0,85	15,42	14,58	N	0,25	N	0,94	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13292	13292	T	A	MI.21286	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	956	319	I	N	aTc/aAc	1,56	0,78	0	probably_damaging	1	neutral	0,34	neutral	4,49	deleterious	-3,83	deleterious	-6,11	medium_impact	3,09	neutral	0,63	damaging	0,12	deleterious	4,47	24,2	0,32	0,5	disease	0,84	disease	0,79	disease	0,63	disease	0,78	6	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,07	medium_impact	1,62	0,68	0,85	15,42	14,58	N	0,29	N	0,98	polymorphism	0,97	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13293	13293	C	A	MI.21287	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	957	319	I	M	atC/atA	7,3	0,98	0	probably_damaging	1	neutral	0,3	neutral	4,52	neutral	-1,23	neutral	-2,38	low_impact	0,9	neutral	0,79	neutral	0,43	deleterious	3,81	23,4	0,6	0,65	neutral	0,49	disease	0,51	disease	0,51	neutral	0,49	0	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,03	medium_impact	-0,38	0,87	0,9	15,42	14,58	N	0,49	N	0,29	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13293	13293	C	G	MI.21288	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	957	319	I	M	atC/atG	7,3	0,98	0	probably_damaging	1	neutral	0,3	neutral	4,52	neutral	-1,23	neutral	-2,38	low_impact	0,9	neutral	0,79	neutral	0,43	deleterious	3,33	22,9	0,6	0,65	neutral	0,49	disease	0,51	disease	0,51	neutral	0,49	0	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,03	medium_impact	-0,38	0,87	0,9	15,42	14,58	N	0,48	N	0,29	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13294	13294	A	T	MI.21289	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	958	320	N	Y	Aac/Tac	-8,07	0	0	probably_damaging	0,98	neutral	1	neutral	4,47	neutral	-2,98	deleterious	-7,06	medium_impact	3,04	neutral	0,72	neutral	0,39	deleterious	3,64	23,2	0,31	0,45	disease	0,82	disease	0,94	disease	0,66	disease	0,79	6	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,85	low_impact	-2,35	high_impact	1,89	medium_impact	1,57	0,43	0,8	17,41	7,06	N	0,2	N	0,99	polymorphism	0,87	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6025	6025	T	G	MI.2129	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	122	41	L	R	cTg/cGg	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,43	deleterious	-7,54	deleterious	-3,69	high_impact	5,13	damaging	0,47	damaging	0,07	deleterious	4,05	23,7	0,17	0,55	disease	0,93	disease	0,9	disease	0,75	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,58	low_impact	-1,48	high_impact	3,64	0,57	0,9	2,53	7	P	0,6	P	0,9	polymorphism	0,83	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13294	13294	A	G	MI.21290	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	958	320	N	D	Aac/Gac	-8,07	0	0	possibly_damaging	0,85	neutral	0,22	neutral	4,57	neutral	-1,66	deleterious	-4,47	medium_impact	2,53	neutral	0,7	neutral	0,55	deleterious	3,55	23,1	0,55	0,6	disease	0,61	disease	0,86	disease	0,71	disease	0,61	2	neutral	0,9	neutral	0,19	NA	0	deleterious	0,61	low_impact	-1,46	medium_impact	-0,07	medium_impact	1,11	0,54	0,8	17,41	7,06	N	0,3	N	0,94	polymorphism	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13294	13294	A	C	MI.21291	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	958	320	N	H	Aac/Cac	-8,07	0	0	probably_damaging	0,98	neutral	0,56	neutral	4,48	neutral	-2,59	deleterious	-4,43	medium_impact	2,58	neutral	0,7	neutral	0,38	deleterious	3,04	22,4	0,49	0,55	disease	0,7	disease	0,9	disease	0,72	disease	0,78	6	deleterious	0,98	neutral	0,29	deleterious	1	deleterious	0,82	low_impact	-2,35	medium_impact	0,29	medium_impact	1,15	0,43	0,8	17,41	7,06	N	0,21	N	0,97	polymorphism	0,96	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13295	13295	A	G	MI.21292	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	959	320	N	S	aAc/aGc	3,85	0,99	0	possibly_damaging	0,74	neutral	0,45	neutral	4,58	neutral	-0,21	deleterious	-4,46	low_impact	1,29	neutral	0,7	neutral	0,67	deleterious	2,03	16,43	0,64	0,7	neutral	0,36	disease	0,75	disease	0,64	disease	0,54	1	neutral	0,74	neutral	0,36	neutral	-3	deleterious	0,52	low_impact	-1,18	medium_impact	0,18	medium_impact	-0,02	0,31	0,8	17,41	7,06	N	0,4	N	0,82	disease_causing	0,89	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13295	13295	A	C	MI.21293	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	959	320	N	T	aAc/aCc	3,85	0,99	0	probably_damaging	0,91	neutral	0,4	neutral	4,63	neutral	-0,92	deleterious	-5,35	medium_impact	3,38	neutral	0,68	neutral	0,47	deleterious	3,66	23,2	0,46	0,55	disease	0,58	disease	0,89	disease	0,66	disease	0,74	5	neutral	0,91	neutral	0,25	deleterious	1	deleterious	0,73	low_impact	-1,7	medium_impact	0,14	medium_impact	1,88	0,47	0,8	17,41	7,06	N	0,43	N	0,94	disease_causing	0,96	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13295	13295	A	T	MI.21294	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	959	320	N	I	aAc/aTc	3,85	0,99	0	probably_damaging	0,97	neutral	0,45	neutral	4,49	deleterious	-3,13	deleterious	-8,02	medium_impact	3,04	neutral	0,69	neutral	0,52	deleterious	4,39	24,1	0,28	0,45	disease	0,84	disease	0,96	disease	0,66	disease	0,78	6	neutral	0,97	neutral	0,24	deleterious	1	deleterious	0,85	low_impact	-2,18	medium_impact	0,18	medium_impact	1,57	0,31	0,8	17,41	7,06	N	0,43	N	0,99	disease_causing	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13296	13296	C	G	MI.21295	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	960	320	N	K	aaC/aaG	5,46	0,99	0	probably_damaging	0,91	neutral	0,3	neutral	4,56	neutral	-1,49	deleterious	-5,35	low_impact	1,51	neutral	0,68	neutral	0,5	deleterious	3,8	23,4	0,58	0,65	disease	0,64	disease	0,93	disease	0,74	disease	0,77	5	neutral	0,92	neutral	0,2	neutral	-2	deleterious	0,73	low_impact	-1,7	medium_impact	0,03	medium_impact	0,18	0,61	0,8	17,41	7,06	N	0,42	N	1	disease_causing	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13296	13296	C	A	MI.21296	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	960	320	N	K	aaC/aaA	5,46	0,99	0	probably_damaging	0,91	neutral	0,3	neutral	4,56	neutral	-1,49	deleterious	-5,35	low_impact	1,51	neutral	0,68	neutral	0,5	deleterious	4,25	23,9	0,58	0,65	disease	0,64	disease	0,93	disease	0,74	disease	0,77	5	neutral	0,92	neutral	0,2	neutral	-2	deleterious	0,73	low_impact	-1,7	medium_impact	0,03	medium_impact	0,18	0,61	0,8	17,41	7,06	N	0,42	N	1	disease_causing	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13297	13297	C	G	MI.21297	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	961	321	Q	E	Caa/Gaa	-3,71	0	0	probably_damaging	1	neutral	0,28	neutral	4,65	neutral	-0,34	deleterious	-2,7	medium_impact	2,31	neutral	0,67	damaging	0,16	deleterious	3,13	22,6	0,55	0,6	disease	0,56	disease	0,82	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,01	medium_impact	0,91	0,61	0,8	18,91	6,94	N	0,24	N	0,92	disease_causing	0,57	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13297	13297	C	A	MI.21298	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	961	321	Q	K	Caa/Aaa	-3,71	0	0	probably_damaging	1	neutral	0,3	neutral	4,64	neutral	-1,08	deleterious	-3,6	medium_impact	2,27	neutral	0,69	damaging	0,12	deleterious	4,11	23,7	0,55	0,6	disease	0,6	disease	0,9	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,03	medium_impact	0,87	0,58	0,8	18,91	6,94	N	0,23	N	0,96	disease_causing	0,74	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13298	13298	A	T	MI.21299	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	962	321	Q	L	cAa/cTa	4,31	0,99	0	probably_damaging	1	neutral	0,68	neutral	4,65	neutral	-1,39	deleterious	-6,31	neutral_impact	0,5	neutral	0,74	neutral	0,29	deleterious	3,85	23,4	0,41	0,5	neutral	0,45	disease	0,8	neutral	0,45	disease	0,51	0	deleterious	1	neutral	0,34	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,41	medium_impact	-0,75	0,28	0,8	18,91	6,94	N	0,32	N	0,96	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8626	8626	T	A	MI.213	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	100	34	S	T	Tcc/Acc	-6,12	0	0	probably_damaging	0,98	neutral	0,71	neutral	4,36	neutral	-0,44	neutral	-0,97	neutral_impact	0,18	neutral	0,88	neutral	0,95	deleterious	1,95	15,92	0,5	0,65	neutral	0,4	neutral	0,25	neutral	0,22	neutral	0,45	1	neutral	0,98	neutral	0,37	neutral	-2	deleterious	0,66	low_impact	-2,36	medium_impact	0,51	medium_impact	-0,94	0,84	0,9	9,73	14,65	N	0,34	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6027	6027	G	C	MI.2130	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	124	42	G	R	Ggc/Cgc	-4,5	0	0	probably_damaging	1	deleterious	0,01	neutral	2,8	deleterious	-4,33	deleterious	-3,73	medium_impact	2,94	damaging	0,6	damaging	0,07	deleterious	3,71	23,3	0,21	0,55	neutral	0,33	disease	0,88	disease	0,53	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,62	0,81	0,9	2,53	7,03	N	0,23	N	0,95	polymorphism	0,99	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13298	13298	A	C	MI.21300	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	962	321	Q	P	cAa/cCa	4,31	0,99	0	probably_damaging	1	neutral	0,22	neutral	4,58	neutral	-2,09	deleterious	-5,41	medium_impact	3,03	neutral	0,62	damaging	0,12	deleterious	3,39	23	0,23	0,45	disease	0,86	disease	0,91	disease	0,77	disease	0,84	7	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,89	low_impact	-3,6	medium_impact	-0,07	medium_impact	1,57	0,38	0,8	18,91	6,94	N	0,45	N	0,95	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13298	13298	A	G	MI.21301	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	962	321	Q	R	cAa/cGa	4,31	0,99	0	probably_damaging	1	neutral	0,35	neutral	4,59	neutral	-1,68	deleterious	-3,6	medium_impact	3,17	neutral	0,64	damaging	0,13	deleterious	3,55	23,1	0,55	0,6	disease	0,72	disease	0,89	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	0,08	medium_impact	1,69	0,51	0,8	18,91	6,94	N	0,44	N	0,85	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13299	13299	A	C	MI.21302	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	963	321	Q	H	caA/caC	5,23	1	0	probably_damaging	1	neutral	0,55	neutral	4,57	neutral	-2,28	deleterious	-4,51	low_impact	1,78	neutral	0,78	damaging	0,17	deleterious	3,97	23,6	0,57	0,65	disease	0,83	disease	0,8	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,83	low_impact	-3,6	medium_impact	0,28	medium_impact	0,42	0,7	0,85	18,91	6,94	N	0,39	N	0,94	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13299	13299	A	T	MI.21303	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	963	321	Q	H	caA/caT	5,23	1	0	probably_damaging	1	neutral	0,55	neutral	4,57	neutral	-2,28	deleterious	-4,51	low_impact	1,78	neutral	0,78	damaging	0,17	deleterious	4,12	23,8	0,57	0,65	disease	0,83	disease	0,8	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,83	low_impact	-3,6	medium_impact	0,28	medium_impact	0,42	0,7	0,85	18,91	6,94	N	0,41	N	0,94	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13300	13300	C	T	MI.21304	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	964	322	P	S	Cca/Tca	-0,04	0,83	0	probably_damaging	1	neutral	0,56	neutral	4,72	neutral	1,39	deleterious	-7,21	medium_impact	2,68	damaging	0,49	damaging	0,03	deleterious	3,89	23,5	0,61	0,65	disease	0,58	disease	0,83	disease	0,68	disease	0,64	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,29	medium_impact	1,25	0,23	0,8	28,03	7,21	N	0,28	N	0,78	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13300	13300	C	G	MI.21305	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	964	322	P	A	Cca/Gca	-0,04	0,83	0	probably_damaging	1	neutral	0,67	neutral	4,67	neutral	0,73	deleterious	-7,21	medium_impact	2,95	damaging	0,5	damaging	0,05	deleterious	3,11	22,5	0,42	0,55	disease	0,62	disease	0,72	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,4	medium_impact	1,49	0,8	0,85	28,03	7,21	N	0,23	N	0,73	disease_causing	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13300	13300	C	A	MI.21306	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	964	322	P	T	Cca/Aca	-0,04	0,83	0	probably_damaging	1	neutral	0,52	neutral	4,69	neutral	1,03	deleterious	-7,21	medium_impact	2,77	damaging	0,5	damaging	0,03	deleterious	3,86	23,5	0,45	0,55	neutral	0,41	disease	0,86	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,25	medium_impact	1,33	0,81	0,85	28,03	7,21	N	0,26	N	0,91	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13301	13301	C	T	MI.21307	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	965	322	P	L	cCa/cTa	4,31	1	0	probably_damaging	1	neutral	0,72	neutral	4,71	neutral	1,29	deleterious	-9,01	medium_impact	2,95	damaging	0,46	damaging	0,02	deleterious	4,36	24,1	0,64	0,7	disease	0,62	disease	0,89	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,46	medium_impact	1,49	0,75	0,85	28,03	7,21	N	0,41	N	0,97	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13301	13301	C	G	MI.21308	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	965	322	P	R	cCa/cGa	4,31	1	0	probably_damaging	1	neutral	0,46	neutral	4,63	neutral	-0,32	deleterious	-8,11	medium_impact	2,84	damaging	0,55	damaging	0,03	deleterious	3,59	23,2	0,35	0,5	disease	0,7	disease	0,93	disease	0,79	disease	0,79	6	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,88	low_impact	-3,6	medium_impact	0,19	medium_impact	1,39	0,59	0,8	28,03	7,21	N	0,39	N	0,64	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13301	13301	C	A	MI.21309	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	965	322	P	Q	cCa/cAa	4,31	1	0	probably_damaging	1	neutral	0,42	neutral	4,65	neutral	0,26	deleterious	-7,21	medium_impact	3,21	damaging	0,48	damaging	0,03	deleterious	4,15	23,8	0,32	0,5	disease	0,69	disease	0,89	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,16	medium_impact	1,73	0,62	0,8	28,03	7,21	N	0,4	N	0,85	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6027	6027	G	T	MI.2131	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	124	42	G	C	Ggc/Tgc	-4,5	0	0	probably_damaging	1	deleterious	0,03	neutral	2,79	deleterious	-5,13	deleterious	-4,11	medium_impact	3,42	neutral	0,62	damaging	0,12	deleterious	3,94	23,5	0,22	0,55	disease	0,56	disease	0,89	neutral	0,41	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-3,58	medium_impact	-0,65	high_impact	2,06	0,54	0,9	2,53	7,03	N	0,29	N	0,98	polymorphism	0,99	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13303	13303	C	T	MI.21310	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	967	323	H	Y	Cac/Tac	-20	0	0	benign	0,01	neutral	1	neutral	4,69	neutral	1,46	neutral	-2,48	neutral_impact	0,06	neutral	0,92	neutral	0,97	neutral	-0,07	1,96	0,56	0,6	disease	0,55	disease	0,6	neutral	0,4	neutral	0,49	0	neutral	0,01	deleterious	1	neutral	-6	neutral	0,26	medium_impact	1,15	high_impact	1,89	low_impact	-1,15	0,37	0,8	1,99	8,37	N	0,3	N	0,03	polymorphism	1	0,02	.	.	.	.	.	.	COSM488748	.	.	.	.	.	.	.	.
chrM	13303	13303	C	G	MI.21311	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	967	323	H	D	Cac/Gac	-20	0	0	possibly_damaging	0,78	neutral	0,23	neutral	4,72	neutral	1,9	deleterious	-6,87	neutral_impact	-0,69	neutral	0,72	neutral	0,6	deleterious	2,43	18,99	0,28	0,45	disease	0,56	disease	0,7	disease	0,76	disease	0,74	5	neutral	0,86	neutral	0,23	neutral	-3	deleterious	0,65	low_impact	-1,27	medium_impact	-0,06	low_impact	-1,83	0,52	0,8	1,99	8,37	N	0,36	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13303	13303	C	A	MI.21312	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	967	323	H	N	Cac/Aac	-20	0	0	possibly_damaging	0,68	neutral	0,33	neutral	4,71	neutral	1,73	deleterious	-5,29	neutral_impact	-1,08	neutral	0,8	neutral	0,83	deleterious	2,45	19,16	0,48	0,55	neutral	0,37	disease	0,55	disease	0,68	neutral	0,5	0	neutral	0,74	neutral	0,33	neutral	-3	deleterious	0,6	low_impact	-1,06	medium_impact	0,06	low_impact	-2,19	0,53	0,8	1,99	8,37	N	0,3	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13304	13304	A	C	MI.21313	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	968	323	H	P	cAc/cCc	-0,96	0	0	probably_damaging	0,92	neutral	0,23	neutral	4,64	neutral	-0,29	deleterious	-7,55	low_impact	1,43	neutral	0,64	neutral	0,37	deleterious	2,97	22,1	0,27	0,45	disease	0,79	disease	0,87	disease	0,77	disease	0,82	6	neutral	0,94	neutral	0,16	neutral	-2	deleterious	0,83	low_impact	-1,75	medium_impact	-0,06	medium_impact	0,1	0,42	0,8	1,99	8,37	N	0,29	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13304	13304	A	G	MI.21314	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	968	323	H	R	cAc/cGc	-0,96	0	0	possibly_damaging	0,72	neutral	0,36	neutral	4,68	neutral	1,12	deleterious	-6,01	neutral_impact	0,68	neutral	0,7	neutral	0,5	deleterious	0,25	5,2	0,49	0,55	disease	0,57	disease	0,74	disease	0,7	disease	0,76	5	neutral	0,75	neutral	0,32	neutral	-3	deleterious	0,66	low_impact	-1,14	medium_impact	0,1	medium_impact	-0,58	0,34	0,8	1,99	8,37	N	0,26	N	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13304	13304	A	T	MI.21315	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	968	323	H	L	cAc/cTc	-0,96	0	0	possibly_damaging	0,44	neutral	0,68	neutral	4,66	neutral	0,6	deleterious	-7,67	neutral_impact	-0,58	neutral	0,77	neutral	0,61	deleterious	0,87	9,88	0,33	0,5	neutral	0,34	disease	0,71	disease	0,66	disease	0,67	3	neutral	0,35	deleterious	0,62	neutral	-3	neutral	0,41	medium_impact	-0,65	medium_impact	0,41	low_impact	-1,73	0,35	0,8	1,99	8,37	N	0,22	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13305	13305	C	A	MI.21316	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	969	323	H	Q	caC/caA	5,46	0,54	0	possibly_damaging	0,78	neutral	0,34	neutral	4,74	neutral	2,16	deleterious	-5,73	neutral_impact	-0,96	neutral	0,76	neutral	0,76	neutral	0,93	10,26	0,49	0,55	neutral	0,38	neutral	0,1	neutral	0,28	neutral	0,24	5	neutral	0,81	neutral	0,28	neutral	-3	deleterious	0,56	low_impact	-1,27	medium_impact	0,07	low_impact	-2,08	0,43	0,8	1,99	8,37	N	0,42	N	0,72	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13305	13305	C	G	MI.21317	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	969	323	H	Q	caC/caG	5,46	0,54	0	possibly_damaging	0,78	neutral	0,34	neutral	4,74	neutral	2,16	deleterious	-5,73	neutral_impact	-0,96	neutral	0,76	neutral	0,76	deleterious	0,59	8,12	0,49	0,55	neutral	0,38	neutral	0,1	neutral	0,28	neutral	0,24	5	neutral	0,81	neutral	0,28	neutral	-3	deleterious	0,56	low_impact	-1,27	medium_impact	0,07	low_impact	-2,08	0,43	0,8	1,99	8,37	N	0,42	N	0,72	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13306	13306	C	A	MI.21318	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	970	324	L	M	Cta/Ata	-0,27	0	0	possibly_damaging	0,76	neutral	0,28	neutral	4,46	neutral	-2,49	neutral	-1,77	medium_impact	2,75	neutral	0,65	neutral	0,45	deleterious	3,96	23,6	0,34	0,5	disease	0,86	disease	0,61	neutral	0,46	disease	0,59	2	neutral	0,82	neutral	0,26	NA	0	deleterious	0,78	low_impact	-1,22	medium_impact	0,01	medium_impact	1,31	0,75	0,85	13,27	7,1	N	0,35	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13306	13306	C	G	MI.21319	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	970	324	L	V	Cta/Gta	-0,27	0	0	possibly_damaging	0,9	neutral	0,64	neutral	4,54	neutral	-1,14	deleterious	-2,67	low_impact	1,63	neutral	0,67	neutral	0,35	deleterious	3,45	23	0,37	0,5	disease	0,64	disease	0,55	disease	0,63	neutral	0,5	0	neutral	0,88	neutral	0,37	neutral	-3	deleterious	0,76	low_impact	-1,65	medium_impact	0,37	medium_impact	0,29	0,59	0,8	13,27	7,1	N	0,19	N	0,81	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6027	6027	G	A	MI.2132	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	124	42	G	S	Ggc/Agc	-4,5	0	0	probably_damaging	1	neutral	1	neutral	2,87	neutral	-2,49	neutral	-2,18	neutral_impact	0,62	neutral	0,64	neutral	0,4	deleterious	2,46	19,2	0,38	0,55	neutral	0,2	neutral	0,38	neutral	0,18	neutral	0,45	1	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,69	low_impact	-3,58	high_impact	1,86	medium_impact	-0,53	0,8	0,9	2,53	7,03	N	0,29	N	0,73	polymorphism	1	0,08	rs879057311	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13307	13307	T	C	MI.21320	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	971	324	L	P	cTa/cCa	-1,65	0	0	probably_damaging	1	neutral	0,38	neutral	4,41	deleterious	-5,1	deleterious	-6,22	high_impact	3,62	damaging	0,6	neutral	0,32	deleterious	3,97	23,6	0,15	0,4	disease	0,83	disease	0,85	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,12	high_impact	2,1	0,51	0,8	13,27	7,1	N	0,3	N	0,99	disease_causing	0,97	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13307	13307	T	A	MI.21321	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	971	324	L	Q	cTa/cAa	-1,65	0	0	probably_damaging	0,99	neutral	0,71	neutral	4,42	deleterious	-4,21	deleterious	-5,31	high_impact	4,04	neutral	0,64	neutral	0,34	deleterious	4,16	23,8	0,18	0,45	disease	0,9	disease	0,86	disease	0,64	disease	0,78	6	deleterious	0,99	neutral	0,36	deleterious	2	deleterious	0,86	low_impact	-2,64	medium_impact	0,45	high_impact	2,49	0,61	0,8	13,27	7,1	N	0,3	N	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13307	13307	T	G	MI.21322	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	971	324	L	R	cTa/cGa	-1,65	0	0	probably_damaging	0,98	neutral	0,69	neutral	4,43	deleterious	-4,83	deleterious	-5,31	high_impact	4,58	damaging	0,6	neutral	0,3	deleterious	4,22	23,9	0,14	0,4	disease	0,89	disease	0,9	disease	0,69	disease	0,79	6	deleterious	0,98	neutral	0,36	deleterious	2	deleterious	0,91	low_impact	-2,35	medium_impact	0,42	high_impact	2,98	0,48	0,8	13,27	7,1	N	0,42	N	1	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13309	13309	G	T	MI.21323	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	973	325	A	S	Gca/Tca	-0,73	0,06	0	probably_damaging	1	neutral	0,55	neutral	4,33	deleterious	-3,41	neutral	-2,48	medium_impact	2,82	neutral	0,63	damaging	0,28	deleterious	3,71	23,3	0,27	0,45	disease	0,61	disease	0,76	disease	0,57	disease	0,54	1	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,28	medium_impact	1,37	0,8	0,85	20,73	7,08	N	0,22	N	0,98	disease_causing	0,91	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13309	13309	G	A	MI.21324	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	973	325	A	T	Gca/Aca	-0,73	0,06	0	probably_damaging	1	neutral	0,49	neutral	4,26	deleterious	-4,31	deleterious	-3,43	medium_impact	3,23	damaging	0,58	neutral	0,43	deleterious	4,23	23,9	0,29	0,45	disease	0,8	disease	0,85	disease	0,59	disease	0,6	2	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	0,22	medium_impact	1,75	0,59	0,8	20,73	7,08	N	0,27	N	0,94	disease_causing	0,96	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13309	13309	G	C	MI.21325	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	973	325	A	P	Gca/Cca	-0,73	0,06	0	probably_damaging	1	neutral	0,28	neutral	4,18	deleterious	-6,74	deleterious	-4,39	high_impact	4,96	damaging	0,54	damaging	0,08	deleterious	3,85	23,4	0,13	0,4	disease	0,64	disease	0,9	disease	0,78	disease	0,79	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,01	high_impact	3,33	0,68	0,85	20,73	7,08	P	0,67	P	0,96	disease_causing	0,99	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13310	13310	C	G	MI.21326	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	974	325	A	G	gCa/gGa	7,07	1	0	probably_damaging	1	neutral	0,4	neutral	4,3	neutral	-2,54	deleterious	-3,5	low_impact	1,94	damaging	0,57	damaging	0,16	deleterious	3,93	23,5	0,23	0,45	disease	0,63	disease	0,76	disease	0,64	disease	0,54	1	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,8	low_impact	-3,6	medium_impact	0,14	medium_impact	0,57	0,8	0,85	20,73	7,08	N	0,48	N	0,82	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13310	13310	C	A	MI.21327	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	974	325	A	E	gCa/gAa	7,07	1	0	probably_damaging	1	neutral	0,45	neutral	4,21	deleterious	-5,03	deleterious	-4,36	high_impact	4,96	damaging	0,57	damaging	0,09	deleterious	4,61	24,4	0,1	0,4	disease	0,89	disease	0,91	disease	0,76	disease	0,82	6	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,18	high_impact	3,33	0,62	0,8	20,73	7,08	P	0,77	P	0,99	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13310	13310	C	T	MI.21328	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	974	325	A	V	gCa/gTa	7,07	1	0	probably_damaging	1	neutral	0,54	neutral	4,25	deleterious	-4,16	deleterious	-3,56	high_impact	3,64	damaging	0,54	damaging	0,07	deleterious	4,45	24,2	0,36	0,5	disease	0,73	disease	0,87	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,27	high_impact	2,12	0,56	0,8	20,73	7,08	P	0,52	P	0,76	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13312	13312	T	A	MI.21329	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	976	326	F	I	Ttc/Atc	-6,01	0	0	possibly_damaging	0,74	neutral	0,45	neutral	4,74	neutral	0,37	deleterious	-5,41	low_impact	1,5	neutral	0,66	neutral	0,6	deleterious	2,8	21,4	0,22	0,45	neutral	0,36	disease	0,83	disease	0,69	disease	0,55	1	neutral	0,74	neutral	0,36	neutral	-3	deleterious	0,5	low_impact	-1,18	medium_impact	0,18	medium_impact	0,17	0,72	0,85	26,87	7,2	N	0,28	N	0,83	polymorphism	0,74	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6028	6028	G	A	MI.2133	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	125	42	G	D	gGc/gAc	4,75	1	0	probably_damaging	1	deleterious	0,01	neutral	2,79	deleterious	-4,44	deleterious	-3,23	high_impact	4,39	damaging	0,58	damaging	0,08	deleterious	3,64	23,2	0,2	0,55	neutral	0,38	disease	0,88	disease	0,62	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-3,58	medium_impact	-0,92	high_impact	2,95	0,36	0,9	2,53	7,03	N	0,44	N	0,97	disease_causing	1	0,21	rs28580752	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13312	13312	T	G	MI.21330	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	976	326	F	V	Ttc/Gtc	-6,01	0	0	possibly_damaging	0,74	neutral	0,54	neutral	4,63	neutral	0,21	deleterious	-6,31	medium_impact	2,4	neutral	0,68	neutral	0,46	deleterious	2,52	19,61	0,21	0,45	neutral	0,46	disease	0,84	disease	0,71	disease	0,57	1	neutral	0,71	neutral	0,4	NA	0	deleterious	0,51	low_impact	-1,18	medium_impact	0,27	medium_impact	0,99	0,7	0,85	26,87	7,2	N	0,25	N	0,91	polymorphism	0,57	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13312	13312	T	C	MI.21331	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	976	326	F	L	Ttc/Ctc	-6,01	0	0	benign	0,08	neutral	0,72	neutral	4,73	neutral	0,75	deleterious	-5,41	low_impact	0,92	neutral	0,68	neutral	0,69	deleterious	2,14	17,11	0,27	0,45	neutral	0,37	disease	0,71	disease	0,68	disease	0,54	1	neutral	0,18	deleterious	0,82	neutral	-6	neutral	0,18	medium_impact	0,26	medium_impact	0,46	medium_impact	-0,36	0,66	0,8	26,87	7,2	N	0,27	N	0,44	polymorphism	0,72	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13313	13313	T	A	MI.21332	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	977	326	F	Y	tTc/tAc	4,54	1	0	possibly_damaging	0,89	neutral	1	neutral	4,64	neutral	-2,75	deleterious	-2,7	medium_impact	2,81	neutral	0,66	neutral	0,45	deleterious	4,16	23,8	0,23	0,45	disease	0,59	disease	0,84	disease	0,66	disease	0,72	4	neutral	0,89	deleterious	0,56	NA	0	deleterious	0,69	low_impact	-1,61	high_impact	1,89	medium_impact	1,36	0,7	0,85	26,87	7,2	N	0,43	N	0,69	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13313	13313	T	G	MI.21333	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	977	326	F	C	tTc/tGc	4,54	1	0	probably_damaging	0,98	neutral	0,19	neutral	4,54	deleterious	-4,31	deleterious	-7,21	high_impact	3,85	neutral	0,67	neutral	0,47	deleterious	4,08	23,7	0,23	0,45	disease	0,84	disease	0,88	disease	0,72	disease	0,77	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,79	low_impact	-2,35	medium_impact	-0,12	high_impact	2,31	0,45	0,8	26,87	7,2	N	0,48	N	0,95	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13313	13313	T	C	MI.21334	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	977	326	F	S	tTc/tCc	4,54	1	0	probably_damaging	0,96	neutral	0,52	neutral	4,57	neutral	-2,31	deleterious	-7,21	high_impact	3,56	neutral	0,72	neutral	0,54	deleterious	4,17	23,8	0,21	0,45	disease	0,62	disease	0,84	disease	0,7	disease	0,73	5	neutral	0,95	neutral	0,28	deleterious	2	deleterious	0,74	low_impact	-2,06	medium_impact	0,25	high_impact	2,05	0,59	0,8	26,87	7,2	N	0,45	N	0,98	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13314	13314	C	A	MI.21335	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	978	326	F	L	ttC/ttA	5,69	1	0	benign	0,08	neutral	0,72	neutral	4,73	neutral	0,75	deleterious	-5,41	low_impact	0,92	neutral	0,68	neutral	0,69	deleterious	2,79	21,3	0,27	0,45	neutral	0,37	disease	0,71	disease	0,68	disease	0,54	1	neutral	0,18	deleterious	0,82	neutral	-6	neutral	0,18	medium_impact	0,26	medium_impact	0,46	medium_impact	-0,36	0,66	0,8	26,87	7,2	N	0,45	N	0,44	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13314	13314	C	G	MI.21336	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	978	326	F	L	ttC/ttG	5,69	1	0	benign	0,08	neutral	0,72	neutral	4,73	neutral	0,75	deleterious	-5,41	low_impact	0,92	neutral	0,68	neutral	0,69	deleterious	2,47	19,27	0,27	0,45	neutral	0,37	disease	0,71	disease	0,68	disease	0,54	1	neutral	0,18	deleterious	0,82	neutral	-6	neutral	0,18	medium_impact	0,26	medium_impact	0,46	medium_impact	-0,36	0,66	0,8	26,87	7,2	N	0,45	N	0,44	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13315	13315	C	G	MI.21337	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	979	327	L	V	Ctg/Gtg	-2,34	0	0	probably_damaging	1	neutral	0,52	neutral	4,49	neutral	-1,67	neutral	-2,3	medium_impact	1,94	neutral	0,67	damaging	0,1	deleterious	3,47	23,1	0,23	0,45	disease	0,62	disease	0,67	disease	0,58	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,25	medium_impact	0,57	0,65	0,8	5,47	11,02	N	0,18	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13315	13315	C	A	MI.21338	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	979	327	L	M	Ctg/Atg	-2,34	0	0	probably_damaging	1	neutral	0,25	neutral	4,45	neutral	-2,55	neutral	-1,29	low_impact	1,52	neutral	0,71	neutral	0,43	deleterious	3,73	23,3	0,24	0,45	disease	0,75	disease	0,51	neutral	0,36	disease	0,52	0	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	-0,03	medium_impact	0,19	0,68	0,85	5,47	11,02	N	0,35	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13316	13316	T	A	MI.21339	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	980	327	L	Q	cTg/cAg	-0,04	0	0	probably_damaging	1	neutral	0,38	neutral	4,38	deleterious	-4,94	deleterious	-4,84	medium_impact	3,19	neutral	0,66	damaging	0,1	deleterious	4,21	23,9	0,14	0,4	disease	0,76	disease	0,85	disease	0,58	disease	0,7	4	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,12	medium_impact	1,71	0,7	0,85	5,47	11,02	N	0,24	N	0,98	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6028	6028	G	T	MI.2134	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	125	42	G	V	gGc/gTc	4,75	1	0	probably_damaging	1	deleterious	0,01	neutral	2,93	neutral	-1,98	deleterious	-4,21	high_impact	3,69	neutral	0,63	damaging	0,09	deleterious	3,63	23,2	0,23	0,55	neutral	0,22	disease	0,82	neutral	0,4	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-3,58	medium_impact	-0,92	high_impact	2,31	0,54	0,9	2,53	7,03	N	0,44	N	0,93	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13316	13316	T	C	MI.21340	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	980	327	L	P	cTg/cCg	-0,04	0	0	probably_damaging	1	neutral	0,22	neutral	4,37	deleterious	-5,63	deleterious	-5,77	high_impact	3,73	neutral	0,6	damaging	0,09	deleterious	3,93	23,5	0,13	0,4	disease	0,92	disease	0,88	disease	0,71	disease	0,82	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,07	high_impact	2,2	0,58	0,8	5,47	11,02	N	0,28	N	0,99	disease_causing	0,63	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13316	13316	T	G	MI.21341	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	980	327	L	R	cTg/cGg	-0,04	0	0	probably_damaging	1	neutral	0,38	neutral	4,38	deleterious	-5,07	deleterious	-4,91	medium_impact	3,39	damaging	0,6	damaging	0,09	deleterious	4,21	23,9	0,12	0,4	disease	0,9	disease	0,91	disease	0,7	disease	0,81	6	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,9	low_impact	-3,6	medium_impact	0,12	medium_impact	1,89	0,5	0,8	5,47	11,02	N	0,24	N	1	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13318	13318	C	G	MI.21342	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	982	328	H	D	Cac/Gac	-20	0	0	probably_damaging	1	neutral	0,3	neutral	4,45	deleterious	-5,22	deleterious	-8,11	high_impact	5,14	damaging	0,38	damaging	0,02	deleterious	3,87	23,5	0,2	0,45	disease	0,91	disease	0,88	disease	0,81	disease	0,84	7	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,03	high_impact	3,49	0,56	0,8	28,69	7,22	N	0,49	N	0,97	polymorphism	0,53	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13318	13318	C	A	MI.21343	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	982	328	H	N	Cac/Aac	-20	0	0	probably_damaging	1	neutral	0,37	neutral	4,48	deleterious	-4,55	deleterious	-6,31	high_impact	4,46	damaging	0,38	damaging	0,02	deleterious	3,9	23,5	0,29	0,45	disease	0,65	disease	0,87	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,11	high_impact	2,87	0,57	0,8	28,69	7,22	N	0,4	N	0,97	polymorphism	0,79	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13318	13318	C	T	MI.21344	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	982	328	H	Y	Cac/Tac	-20	0	0	probably_damaging	1	neutral	1	neutral	4,55	neutral	-2,19	deleterious	-5,41	high_impact	3,6	damaging	0,38	damaging	0,02	deleterious	3,71	23,3	0,27	0,45	disease	0,69	disease	0,91	disease	0,77	disease	0,77	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,84	low_impact	-3,6	high_impact	1,89	high_impact	2,09	0,51	0,8	28,69	7,22	N	0,37	N	1	polymorphism	0,75	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13319	13319	A	T	MI.21345	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	983	328	H	L	cAc/cTc	7,07	1	0	probably_damaging	1	neutral	0,73	neutral	4,65	deleterious	-3,24	deleterious	-9,91	medium_impact	2,96	damaging	0,41	damaging	0,02	deleterious	3,86	23,5	0,19	0,45	disease	0,66	disease	0,92	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,47	medium_impact	1,5	0,46	0,8	28,69	7,22	P	0,56	P	0,97	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13319	13319	A	C	MI.21346	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	983	328	H	P	cAc/cCc	7,07	1	0	probably_damaging	1	neutral	0,27	neutral	4,45	deleterious	-6,27	deleterious	-9,01	high_impact	5,14	damaging	0,34	damaging	0,04	deleterious	3,3	22,9	0,23	0,45	disease	0,94	disease	0,9	disease	0,84	disease	0,83	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,01	high_impact	3,49	0,49	0,8	28,69	7,22	P	0,69	P	0,97	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13319	13319	A	G	MI.21347	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	983	328	H	R	cAc/cGc	7,07	1	0	probably_damaging	1	neutral	0,42	neutral	4,46	deleterious	-5,06	deleterious	-7,21	high_impact	5,14	damaging	0,43	damaging	0,03	deleterious	3,02	22,3	0,26	0,45	disease	0,89	disease	0,9	disease	0,79	disease	0,83	7	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,16	high_impact	3,49	0,52	0,8	28,69	7,22	P	0,7	P	0,99	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13320	13320	C	G	MI.21348	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	984	328	H	Q	caC/caG	8,44	1	0	probably_damaging	1	neutral	0,38	neutral	4,51	neutral	-2,15	deleterious	-7,21	high_impact	4,17	damaging	0,43	damaging	0,02	deleterious	3,55	23,1	0,33	0,5	disease	0,73	disease	0,88	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,12	high_impact	2,61	0,68	0,85	28,69	7,22	P	0,63	P	0,95	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13320	13320	C	A	MI.21349	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	984	328	H	Q	caC/caA	8,44	1	0	probably_damaging	1	neutral	0,38	neutral	4,51	neutral	-2,15	deleterious	-7,21	high_impact	4,17	damaging	0,43	damaging	0,02	deleterious	3,97	23,6	0,33	0,5	disease	0,73	disease	0,88	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,12	high_impact	2,61	0,68	0,85	28,69	7,22	P	0,63	P	0,95	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6028	6028	G	C	MI.2135	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	125	42	G	A	gGc/gCc	4,75	1	0	probably_damaging	1	neutral	0,23	neutral	3,01	neutral	-1,29	neutral	-2,36	low_impact	1,36	neutral	0,64	damaging	0,22	neutral	1,78	14,88	0,47	0,55	neutral	0,27	neutral	0,49	neutral	0,2	neutral	0,44	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,71	low_impact	-3,58	medium_impact	-0,1	medium_impact	0,16	0,57	0,9	2,53	7,03	P	0,52	P	0,64	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13321	13321	A	C	MI.21350	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	985	329	I	L	Atc/Ctc	-0,27	0,39	0	benign	0,38	neutral	0,71	neutral	4,92	neutral	1,86	neutral	-1,7	neutral_impact	-0,3	neutral	0,63	neutral	0,69	deleterious	3,65	23,2	0,25	0,45	neutral	0,39	neutral	0,41	disease	0,66	neutral	0,43	1	neutral	0,28	deleterious	0,67	neutral	-6	deleterious	0,64	medium_impact	-0,54	medium_impact	0,45	low_impact	-1,48	0,67	0,85	5,47	10,14	N	0,32	N	0,86	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13321	13321	A	T	MI.21351	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	985	329	I	F	Atc/Ttc	-0,27	0,39	0	probably_damaging	0,91	neutral	0,74	neutral	4,61	neutral	-2,42	deleterious	-3,5	medium_impact	2,86	neutral	0,61	neutral	0,38	deleterious	3,67	23,2	0,21	0,45	disease	0,75	disease	0,82	disease	0,68	disease	0,69	4	neutral	0,9	neutral	0,42	deleterious	1	deleterious	0,8	low_impact	-1,7	medium_impact	0,48	medium_impact	1,41	0,75	0,85	5,47	10,14	N	0,24	N	0,96	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13321	13321	A	G	MI.21352	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	985	329	I	V	Atc/Gtc	-0,27	0,39	0	benign	0,08	neutral	0,53	neutral	4,62	neutral	-0,32	neutral	-0,86	medium_impact	2,12	neutral	0,61	neutral	0,48	deleterious	2,93	22	0,36	0,5	disease	0,62	neutral	0,45	disease	0,59	disease	0,61	2	neutral	0,4	deleterious	0,73	neutral	-3	deleterious	0,67	medium_impact	0,26	medium_impact	0,26	medium_impact	0,73	0,57	0,8	5,47	10,14	N	0,31	N	0,74	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13322	13322	T	C	MI.21353	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	986	329	I	T	aTc/aCc	8,44	1	0	possibly_damaging	0,87	neutral	0,42	neutral	4,58	neutral	-2	deleterious	-4,4	medium_impact	2,31	neutral	0,61	neutral	0,4	deleterious	3,41	23	0,3	0,45	disease	0,77	disease	0,77	disease	0,66	disease	0,7	4	neutral	0,86	neutral	0,28	NA	0	deleterious	0,8	low_impact	-1,53	medium_impact	0,16	medium_impact	0,91	0,6	0,8	5,47	10,14	P	0,52	P	0,96	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13322	13322	T	G	MI.21354	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	986	329	I	S	aTc/aGc	8,44	1	0	possibly_damaging	0,9	neutral	0,43	neutral	4,54	neutral	-2,49	deleterious	-5,26	high_impact	3,56	neutral	0,62	neutral	0,47	deleterious	4,32	24	0,21	0,45	disease	0,71	disease	0,83	disease	0,66	disease	0,7	4	neutral	0,9	neutral	0,27	deleterious	1	deleterious	0,81	low_impact	-1,65	medium_impact	0,17	high_impact	2,05	0,48	0,8	5,47	10,14	P	0,58	P	0,96	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13322	13322	T	A	MI.21355	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	986	329	I	N	aTc/aAc	8,44	1	0	probably_damaging	0,96	neutral	0,31	neutral	4,51	deleterious	-3,62	deleterious	-6,17	high_impact	3,9	damaging	0,6	neutral	0,43	deleterious	4,44	24,2	0,19	0,45	disease	0,53	disease	0,85	disease	0,67	disease	0,72	4	neutral	0,97	neutral	0,18	deleterious	2	deleterious	0,77	low_impact	-2,06	medium_impact	0,04	high_impact	2,36	0,63	0,8	5,47	10,14	P	0,55	P	0,99	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13323	13323	C	A	MI.21356	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	987	329	I	M	atC/atA	7,3	1	0	possibly_damaging	0,49	neutral	0,25	neutral	4,71	neutral	0,35	neutral	-2,46	neutral_impact	0,6	neutral	0,73	neutral	0,86	deleterious	3,73	23,3	0,25	0,45	neutral	0,47	disease	0,51	disease	0,57	neutral	0,46	1	neutral	0,73	neutral	0,38	neutral	-3	deleterious	0,69	medium_impact	-0,73	medium_impact	-0,03	medium_impact	-0,66	0,72	0,85	5,47	10,14	P	0,53	P	0,76	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13323	13323	C	G	MI.21357	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	987	329	I	M	atC/atG	7,3	1	0	possibly_damaging	0,49	neutral	0,25	neutral	4,71	neutral	0,35	neutral	-2,46	neutral_impact	0,6	neutral	0,73	neutral	0,86	deleterious	3,35	22,9	0,25	0,45	neutral	0,47	disease	0,51	disease	0,57	neutral	0,46	1	neutral	0,73	neutral	0,38	neutral	-3	deleterious	0,69	medium_impact	-0,73	medium_impact	-0,03	medium_impact	-0,66	0,72	0,85	5,47	10,14	P	0,53	P	0,76	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13324	13324	T	A	MI.21358	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	988	330	C	S	Tgt/Agt	-1,88	0	0	probably_damaging	1	neutral	0,47	neutral	4,63	neutral	0,11	deleterious	-9,01	low_impact	1,21	neutral	0,61	damaging	0,25	deleterious	3,52	23,1	0,34	0,5	disease	0,56	disease	0,63	disease	0,56	neutral	0,49	0	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	0,2	medium_impact	-0,1	0,74	0,85	24,54	7,17	N	0,26	N	0,45	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13324	13324	T	C	MI.21359	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	988	330	C	R	Tgt/Cgt	-1,88	0	0	probably_damaging	1	neutral	0,38	neutral	4,61	neutral	-1,4	deleterious	-10,81	high_impact	3,62	damaging	0,41	damaging	0,05	deleterious	3,46	23	0,27	0,45	disease	0,84	disease	0,95	disease	0,78	disease	0,85	7	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,12	high_impact	2,1	0,49	0,8	24,54	7,17	P	0,53	P	0,89	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6030	6030	C	G	MI.2136	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	127	43	Q	E	Cag/Gag	-8,43	0	0	probably_damaging	0,95	deleterious	0,04	neutral	2,98	neutral	-2,22	neutral	-1,24	medium_impact	2,56	neutral	0,6	neutral	0,37	deleterious	2,95	22	0,55	0,6	neutral	0,23	disease	0,6	neutral	0,31	neutral	0,44	1	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,7	low_impact	-1,96	medium_impact	-0,58	medium_impact	1,27	0,59	0,9	2,73	6,75	N	0,42	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13324	13324	T	G	MI.21360	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	988	330	C	G	Tgt/Ggt	-1,88	0	0	probably_damaging	1	neutral	0,44	neutral	4,61	neutral	-0,64	deleterious	-10,81	medium_impact	2,92	damaging	0,47	damaging	0,06	deleterious	3,31	22,9	0,31	0,45	disease	0,74	disease	0,91	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,18	medium_impact	1,46	0,64	0,8	24,54	7,17	N	0,29	N	0,79	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13325	13325	G	A	MI.21361	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	989	330	C	Y	tGt/tAt	4,31	1	0	probably_damaging	1	neutral	0,87	neutral	4,71	neutral	0	deleterious	-9,91	medium_impact	2,05	damaging	0,43	damaging	0,04	deleterious	3,6	23,2	0,31	0,45	disease	0,7	disease	0,94	disease	0,72	disease	0,85	7	deleterious	1	neutral	0,44	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,69	medium_impact	0,67	0,71	0,85	24,54	7,17	N	0,42	N	0,94	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13325	13325	G	T	MI.21362	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	989	330	C	F	tGt/tTt	4,31	1	0	probably_damaging	1	neutral	0,79	neutral	4,67	neutral	2,31	deleterious	-9,91	low_impact	1,06	damaging	0,44	damaging	0,05	deleterious	3,93	23,5	0,32	0,5	neutral	0,47	disease	0,93	disease	0,68	disease	0,56	1	deleterious	1	neutral	0,4	neutral	-2	deleterious	0,81	low_impact	-3,6	medium_impact	0,55	medium_impact	-0,23	0,64	0,8	24,54	7,17	N	0,41	N	0,95	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13325	13325	G	C	MI.21363	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	989	330	C	S	tGt/tCt	4,31	1	0	probably_damaging	1	neutral	0,47	neutral	4,63	neutral	0,11	deleterious	-9,01	low_impact	1,21	neutral	0,61	damaging	0,25	deleterious	3,21	22,7	0,34	0,5	disease	0,56	disease	0,63	disease	0,56	neutral	0,49	0	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	0,2	medium_impact	-0,1	0,74	0,85	24,54	7,17	N	0,34	N	0,45	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13326	13326	T	A	MI.21364	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	990	330	C	W	tgT/tgA	5,69	1	0,03	probably_damaging	1	neutral	0,16	neutral	4,6	neutral	-1,72	deleterious	-9,91	medium_impact	2,92	damaging	0,46	damaging	0,04	deleterious	4,37	24,1	0,24	0,45	disease	0,77	disease	0,94	disease	0,74	disease	0,86	7	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	-0,17	medium_impact	1,46	0,52	0,8	24,54	7,17	P	0,5	N	0,96	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13326	13326	T	G	MI.21365	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	990	330	C	W	tgT/tgG	5,69	1	0,03	probably_damaging	1	neutral	0,16	neutral	4,6	neutral	-1,72	deleterious	-9,91	medium_impact	2,92	damaging	0,46	damaging	0,04	deleterious	4,25	23,9	0,24	0,45	disease	0,77	disease	0,94	disease	0,74	disease	0,86	7	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	-0,17	medium_impact	1,46	0,52	0,8	24,54	7,17	P	0,49	N	0,96	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13327	13327	A	T	MI.21366	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	991	331	T	S	Acc/Tcc	-2,11	0	0	probably_damaging	1	neutral	0,56	neutral	4,59	neutral	-0,76	deleterious	-2,9	medium_impact	1,99	neutral	0,79	neutral	0,5	deleterious	3,4	23	0,36	0,5	disease	0,56	disease	0,64	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,7	low_impact	-3,6	medium_impact	0,29	medium_impact	0,62	0,7	0,85	4,15	7,89	N	0,19	N	0,89	disease_causing	0,85	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13327	13327	A	C	MI.21367	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	991	331	T	P	Acc/Ccc	-2,11	0	0	probably_damaging	1	neutral	0,22	neutral	4,41	deleterious	-5,1	deleterious	-4,65	high_impact	4,66	neutral	0,76	neutral	0,37	deleterious	3,59	23,2	0,19	0,45	disease	0,91	disease	0,81	disease	0,75	disease	0,82	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	-0,07	high_impact	3,05	0,55	0,8	4,15	7,89	P	0,59	P	0,97	disease_causing	0,99	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13327	13327	A	G	MI.21368	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	991	331	T	A	Acc/Gcc	-2,11	0	0	probably_damaging	1	neutral	0,69	neutral	4,55	neutral	-0,33	deleterious	-3,8	medium_impact	2,38	neutral	0,87	neutral	0,54	deleterious	3,54	23,1	0,35	0,5	disease	0,52	disease	0,55	disease	0,63	disease	0,63	3	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,67	low_impact	-3,6	medium_impact	0,42	medium_impact	0,97	0,5	0,8	4,15	7,89	N	0,23	N	0,69	disease_causing	0,94	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13328	13328	C	T	MI.21369	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	992	331	T	I	aCc/aTc	8,44	1	0	probably_damaging	1	neutral	0,46	neutral	4,57	neutral	-2,21	deleterious	-4,38	medium_impact	3,1	neutral	0,68	neutral	0,57	deleterious	4	23,6	0,25	0,45	disease	0,74	disease	0,87	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,19	medium_impact	1,63	0,58	0,8	4,15	7,89	P	0,51	P	0,95	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6030	6030	C	A	MI.2137	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	127	43	Q	K	Cag/Aag	-8,43	0	0	probably_damaging	0,98	neutral	0,19	neutral	2,95	neutral	-1,78	neutral	-1,64	medium_impact	2,84	neutral	0,63	neutral	0,39	deleterious	3,78	23,4	0,48	0,55	neutral	0,2	disease	0,75	neutral	0,34	disease	0,6	2	deleterious	0,98	neutral	0,11	deleterious	1	deleterious	0,71	low_impact	-2,35	medium_impact	-0,16	medium_impact	1,52	0,58	0,9	2,73	6,75	N	0,42	N	0,83	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13328	13328	C	A	MI.21370	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	992	331	T	N	aCc/aAc	8,44	1	0	probably_damaging	1	neutral	0,32	neutral	4,41	neutral	-0,04	deleterious	-3,48	medium_impact	2,47	neutral	0,76	neutral	0,68	deleterious	3,63	23,2	0,33	0,5	neutral	0,45	disease	0,68	disease	0,58	neutral	0,5	0	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,68	low_impact	-3,6	medium_impact	0,05	medium_impact	1,05	0,77	0,85	4,15	7,89	P	0,51	P	0,93	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13328	13328	C	G	MI.21371	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	992	331	T	S	aCc/aGc	8,44	1	0	probably_damaging	1	neutral	0,56	neutral	4,59	neutral	-0,76	deleterious	-2,9	medium_impact	1,99	neutral	0,79	neutral	0,5	deleterious	3,54	23,1	0,36	0,5	disease	0,56	disease	0,64	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,7	low_impact	-3,6	medium_impact	0,29	medium_impact	0,62	0,7	0,85	4,15	7,89	N	0,45	N	0,89	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13330	13330	C	A	MI.21372	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	994	332	H	N	Cac/Aac	-11,28	0	0	probably_damaging	1	neutral	0,39	neutral	3,89	deleterious	-5,8	deleterious	-6,31	high_impact	4,9	damaging	0,39	damaging	0,07	deleterious	3,97	23,6	0,22	0,45	disease	0,82	disease	0,84	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,13	high_impact	3,27	0,3	0,8	29,02	7,19	P	0,53	P	0,97	polymorphism	0,75	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13330	13330	C	G	MI.21373	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	994	332	H	D	Cac/Gac	-11,28	0	0	probably_damaging	1	neutral	0,24	neutral	3,89	deleterious	-6,33	deleterious	-8,11	high_impact	5,25	damaging	0,51	damaging	0,07	deleterious	3,9	23,5	0,19	0,45	disease	0,86	disease	0,86	disease	0,83	disease	0,82	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,04	high_impact	3,59	0,34	0,8	29,02	7,19	P	0,54	P	0,97	disease_causing	0,53	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13330	13330	C	T	MI.21374	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	994	332	H	Y	Cac/Tac	-11,28	0	0	probably_damaging	1	neutral	1	neutral	4,25	deleterious	-4,22	deleterious	-5,41	high_impact	4,09	damaging	0,46	damaging	0,06	deleterious	3,79	23,4	0,23	0,45	disease	0,75	disease	0,89	disease	0,75	disease	0,77	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,84	low_impact	-3,6	high_impact	1,89	high_impact	2,53	0,44	0,8	29,02	7,19	N	0,32	N	1	polymorphism	0,7	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13331	13331	A	G	MI.21375	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	995	332	H	R	cAc/cGc	5,46	1	0	probably_damaging	1	neutral	0,35	neutral	3,89	deleterious	-6,4	deleterious	-7,21	high_impact	5,25	damaging	0,49	damaging	0,07	deleterious	3,06	22,4	0,21	0,45	disease	0,92	disease	0,9	disease	0,81	disease	0,85	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,08	high_impact	3,59	0,38	0,8	29,02	7,19	P	0,66	P	0,99	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13331	13331	A	C	MI.21376	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	995	332	H	P	cAc/cCc	5,46	1	0	probably_damaging	1	neutral	0,21	neutral	3,88	deleterious	-7,57	deleterious	-9,01	high_impact	5,25	damaging	0,44	damaging	0,08	deleterious	3,31	22,9	0,18	0,45	disease	0,96	disease	0,88	disease	0,84	disease	0,83	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,09	high_impact	3,59	0,25	0,8	29,02	7,19	P	0,65	P	0,97	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13331	13331	A	T	MI.21377	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	995	332	H	L	cAc/cTc	5,46	1	0	probably_damaging	1	neutral	0,7	neutral	3,95	deleterious	-5,52	deleterious	-9,91	high_impact	5,25	damaging	0,39	damaging	0,08	deleterious	3,91	23,5	0,16	0,45	disease	0,91	disease	0,91	disease	0,77	disease	0,84	7	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,44	high_impact	3,59	0,38	0,8	29,02	7,19	P	0,73	P	0,97	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13332	13332	C	A	MI.21378	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	996	332	H	Q	caC/caA	8,44	1	0	probably_damaging	1	neutral	0,3	neutral	3,97	deleterious	-5,94	deleterious	-7,21	high_impact	5,25	damaging	0,45	damaging	0,07	deleterious	3,93	23,5	0,24	0,45	disease	0,91	disease	0,85	disease	0,78	disease	0,82	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,03	high_impact	3,59	0,39	0,8	29,02	7,19	P	0,68	P	0,95	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13332	13332	C	G	MI.21379	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	996	332	H	Q	caC/caG	8,44	1	0	probably_damaging	1	neutral	0,3	neutral	3,97	deleterious	-5,94	deleterious	-7,21	high_impact	5,25	damaging	0,45	damaging	0,07	deleterious	3,59	23,2	0,24	0,45	disease	0,91	disease	0,85	disease	0,78	disease	0,82	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,03	high_impact	3,59	0,39	0,8	29,02	7,19	P	0,67	P	0,95	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6031	6031	A	C	MI.2138	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	128	43	Q	P	cAg/cCg	7,3	1	0	probably_damaging	0,99	deleterious	0,01	neutral	2,99	deleterious	-4,19	deleterious	-2,66	high_impact	4,08	damaging	0,54	neutral	0,31	deleterious	3,31	22,9	0,15	0,55	neutral	0,5	disease	0,87	neutral	0,37	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,64	medium_impact	-0,92	high_impact	2,67	0,4	0,9	2,73	6,75	P	0,5	N	0,84	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13333	13333	G	A	MI.21380	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	997	333	A	T	Gcc/Acc	-0,73	0,02	0	probably_damaging	1	neutral	0,44	neutral	4,41	deleterious	-4,06	deleterious	-3,6	high_impact	4,76	damaging	0,4	damaging	0,11	deleterious	4,33	24	0,2	0,45	disease	0,86	disease	0,85	disease	0,56	disease	0,73	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,18	high_impact	3,15	0,5	0,8	28,19	7,26	P	0,62	P	0,94	disease_causing	1	0,27	.	.	.	.	.	.	COSM1155534	.	.	.	.	.	.	.	.
chrM	13333	13333	G	T	MI.21381	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	997	333	A	S	Gcc/Tcc	-0,73	0,02	0	probably_damaging	1	neutral	0,46	neutral	4,43	neutral	-2,77	deleterious	-2,7	medium_impact	2,35	damaging	0,42	damaging	0,19	deleterious	3,72	23,3	0,2	0,45	disease	0,71	disease	0,79	disease	0,58	disease	0,54	1	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,19	medium_impact	0,94	0,61	0,8	28,19	7,26	N	0,43	N	0,98	disease_causing	0,99	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13333	13333	G	C	MI.21382	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	997	333	A	P	Gcc/Ccc	-0,73	0,02	0	probably_damaging	1	neutral	0,22	neutral	4,37	deleterious	-6,69	deleterious	-4,51	high_impact	5,11	damaging	0,54	damaging	0,09	deleterious	3,88	23,5	0,15	0,4	disease	0,94	disease	0,89	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,07	high_impact	3,47	0,62	0,8	28,19	7,26	P	0,63	P	0,96	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13334	13334	C	A	MI.21383	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	998	333	A	D	gCc/gAc	5,92	1	0	probably_damaging	1	neutral	0,2	neutral	4,37	deleterious	-6,84	deleterious	-5,41	high_impact	5,11	neutral	0,62	damaging	0,1	deleterious	4,59	24,4	0,13	0,4	disease	0,92	disease	0,93	disease	0,73	disease	0,83	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,1	high_impact	3,47	0,55	0,8	28,19	7,26	P	0,72	P	0,95	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13334	13334	C	T	MI.21384	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	998	333	A	V	gCc/gTc	5,92	1	0	probably_damaging	1	neutral	0,52	neutral	4,49	deleterious	-3,43	deleterious	-3,6	high_impact	4,55	damaging	0,45	damaging	0,06	deleterious	4,56	24,4	0,27	0,45	disease	0,76	disease	0,87	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,25	high_impact	2,95	0,57	0,8	28,19	7,26	P	0,63	P	0,76	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13334	13334	C	G	MI.21385	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	998	333	A	G	gCc/gGc	5,92	1	0	probably_damaging	1	neutral	0,41	neutral	4,6	neutral	-1,36	deleterious	-3,61	medium_impact	2,54	damaging	0,52	damaging	0,13	deleterious	4,04	23,7	0,19	0,45	disease	0,56	disease	0,85	disease	0,58	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,15	medium_impact	1,12	0,76	0,85	28,19	7,26	N	0,48	N	0,82	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13336	13336	T	A	MI.21386	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1000	334	F	I	Ttc/Atc	-10,6	0	0	possibly_damaging	0,81	neutral	0,41	neutral	4,4	neutral	-1,31	deleterious	-5,41	medium_impact	2,92	damaging	0,4	neutral	0,59	deleterious	4,45	24,2	0,21	0,45	disease	0,57	disease	0,88	disease	0,69	disease	0,73	5	neutral	0,81	neutral	0,3	NA	0	deleterious	0,79	low_impact	-1,34	medium_impact	0,15	medium_impact	1,46	0,63	0,8	28,19	7,18	P	0,57	P	0,95	disease_causing	0,94	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13336	13336	T	G	MI.21387	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1000	334	F	V	Ttc/Gtc	-10,6	0	0	possibly_damaging	0,81	neutral	0,5	neutral	4,46	neutral	-1,64	deleterious	-6,31	medium_impact	3,06	damaging	0,35	neutral	0,44	deleterious	4,17	23,8	0,22	0,45	disease	0,56	disease	0,88	disease	0,7	disease	0,74	5	neutral	0,79	neutral	0,35	NA	0	deleterious	0,77	low_impact	-1,34	medium_impact	0,23	medium_impact	1,59	0,64	0,8	28,19	7,18	P	0,58	P	0,95	disease_causing	0,97	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13336	13336	T	C	MI.21388	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1000	334	F	L	Ttc/Ctc	-10,6	0	0	benign	0,12	neutral	0,7	neutral	4,59	neutral	-0,05	deleterious	-5,41	medium_impact	2,06	damaging	0,25	neutral	0,5	deleterious	4,1	23,7	0,33	0,5	neutral	0,36	disease	0,81	disease	0,65	disease	0,63	3	neutral	0,19	deleterious	0,79	neutral	-3	deleterious	0,72	medium_impact	0,08	medium_impact	0,44	medium_impact	0,68	0,66	0,8	28,19	7,18	P	0,86	P	0,92	disease_causing	0,95	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13337	13337	T	G	MI.21389	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1001	334	F	C	tTc/tGc	7,3	1	0	probably_damaging	0,99	neutral	0,21	neutral	4,31	deleterious	-4,98	deleterious	-7,21	high_impact	3,58	damaging	0,4	neutral	0,47	deleterious	4,14	23,8	0,25	0,45	disease	0,89	disease	0,88	disease	0,72	disease	0,81	6	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,81	low_impact	-2,64	medium_impact	-0,09	high_impact	2,07	0,44	0,8	28,19	7,18	P	0,71	P	0,99	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6031	6031	A	T	MI.2139	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	128	43	Q	L	cAg/cTg	7,3	1	0	probably_damaging	0,98	deleterious	0,01	neutral	3,05	neutral	-2,73	deleterious	-3,02	medium_impact	2,63	neutral	0,61	neutral	0,39	deleterious	3,8	23,4	0,34	0,55	neutral	0,18	disease	0,75	neutral	0,3	disease	0,59	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,71	low_impact	-2,35	medium_impact	-0,92	medium_impact	1,33	0,35	0,9	2,73	6,75	P	0,54	P	0,71	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13337	13337	T	C	MI.21390	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1001	334	F	S	tTc/tCc	7,3	1	0	probably_damaging	0,97	neutral	0,44	neutral	4,37	deleterious	-4,26	deleterious	-7,2	medium_impact	3,14	damaging	0,44	neutral	0,7	deleterious	4,26	23,9	0,24	0,45	disease	0,82	disease	0,85	disease	0,69	disease	0,71	4	neutral	0,97	neutral	0,24	deleterious	1	deleterious	0,82	low_impact	-2,18	medium_impact	0,18	medium_impact	1,67	0,56	0,8	28,19	7,18	P	0,66	P	0,97	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13337	13337	T	A	MI.21391	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1001	334	F	Y	tTc/tAc	7,3	1	0	probably_damaging	0,92	neutral	1	neutral	4,41	deleterious	-3,33	deleterious	-2,7	medium_impact	3,41	damaging	0,5	neutral	0,47	deleterious	4,24	23,9	0,22	0,45	disease	0,77	disease	0,82	disease	0,65	disease	0,64	3	neutral	0,92	deleterious	0,54	deleterious	1	deleterious	0,81	low_impact	-1,75	high_impact	1,89	medium_impact	1,91	0,71	0,85	28,19	7,18	P	0,56	P	0,88	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13338	13338	C	G	MI.21392	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1002	334	F	L	ttC/ttG	7,3	1	0	benign	0,12	neutral	0,7	neutral	4,59	neutral	-0,05	deleterious	-5,41	medium_impact	2,06	damaging	0,25	neutral	0,5	deleterious	4,41	24,1	0,33	0,5	neutral	0,36	disease	0,81	disease	0,65	disease	0,63	3	neutral	0,19	deleterious	0,79	neutral	-3	deleterious	0,72	medium_impact	0,08	medium_impact	0,44	medium_impact	0,68	0,66	0,8	28,19	7,18	P	0,94	P	0,92	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13338	13338	C	A	MI.21393	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1002	334	F	L	ttC/ttA	7,3	1	0	benign	0,12	neutral	0,7	neutral	4,59	neutral	-0,05	deleterious	-5,41	medium_impact	2,06	damaging	0,25	neutral	0,5	deleterious	4,71	24,6	0,33	0,5	neutral	0,36	disease	0,81	disease	0,65	disease	0,63	3	neutral	0,19	deleterious	0,79	neutral	-3	deleterious	0,72	medium_impact	0,08	medium_impact	0,44	medium_impact	0,68	0,66	0,8	28,19	7,18	P	0,94	P	0,92	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13339	13339	T	A	MI.21394	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1003	335	F	I	Ttc/Atc	-0,27	0,69	0	probably_damaging	1	neutral	0,59	neutral	4,55	neutral	-2,32	deleterious	-5,41	high_impact	4,83	damaging	0,4	damaging	0,15	deleterious	4,36	24,1	0,16	0,45	disease	0,62	disease	0,88	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,32	high_impact	3,21	0,54	0,8	26,87	7,22	P	0,72	P	0,95	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13339	13339	T	C	MI.21395	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1003	335	F	L	Ttc/Ctc	-0,27	0,69	0	probably_damaging	1	neutral	0,89	neutral	4,53	neutral	-2,87	deleterious	-5,41	high_impact	5,17	damaging	0,37	damaging	0,12	deleterious	4,03	23,7	0,32	0,5	disease	0,66	disease	0,81	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,73	high_impact	3,52	0,61	0,8	26,87	7,22	P	0,68	P	0,92	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13339	13339	T	G	MI.21396	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1003	335	F	V	Ttc/Gtc	-0,27	0,69	0	probably_damaging	1	neutral	0,53	neutral	4,54	neutral	-2,17	deleterious	-6,31	high_impact	4,37	damaging	0,34	damaging	0,11	deleterious	4,05	23,7	0,2	0,45	disease	0,63	disease	0,88	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,26	high_impact	2,79	0,53	0,8	26,87	7,22	P	0,59	P	0,95	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13340	13340	T	G	MI.21397	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1004	335	F	C	tTc/tGc	7,3	1	0	probably_damaging	1	neutral	0,28	neutral	4,43	deleterious	-6,06	deleterious	-7,21	high_impact	5,17	damaging	0,44	damaging	0,15	deleterious	4,14	23,8	0,16	0,45	disease	0,85	disease	0,89	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,01	high_impact	3,52	0,38	0,8	26,87	7,22	P	0,72	P	0,99	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13340	13340	T	A	MI.21398	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1004	335	F	Y	tTc/tAc	7,3	1	0	probably_damaging	1	neutral	1	neutral	4,45	neutral	-2,78	deleterious	-2,7	medium_impact	3,21	damaging	0,43	damaging	0,14	deleterious	4,29	24	0,22	0,45	disease	0,77	disease	0,84	disease	0,64	disease	0,71	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,82	low_impact	-3,6	high_impact	1,89	medium_impact	1,73	0,64	0,8	26,87	7,22	P	0,67	P	0,88	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13340	13340	T	C	MI.21399	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1004	335	F	S	tTc/tCc	7,3	1	0	probably_damaging	1	neutral	0,52	neutral	4,55	neutral	-2,7	deleterious	-7,21	high_impact	3,98	damaging	0,44	damaging	0,15	deleterious	4,3	24	0,16	0,45	disease	0,73	disease	0,85	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,25	high_impact	2,43	0,54	0,8	26,87	7,22	P	0,66	P	0,97	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8626	8626	T	G	MI.214	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	100	34	S	A	Tcc/Gcc	-6,12	0	0	probably_damaging	0,97	neutral	0,81	neutral	4,34	neutral	-0,62	neutral	-1,42	low_impact	1,28	neutral	0,89	neutral	0,49	deleterious	2,36	18,57	0,5	0,65	neutral	0,47	neutral	0,33	neutral	0,41	neutral	0,45	1	neutral	0,96	neutral	0,42	neutral	-2	deleterious	0,69	low_impact	-2,19	medium_impact	0,65	medium_impact	0	0,68	0,9	9,73	14,65	N	0,24	N	0,27	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6031	6031	A	G	MI.2140	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	128	43	Q	R	cAg/cGg	7,3	1	0	probably_damaging	0,98	neutral	0,16	neutral	2,97	neutral	-2,37	neutral	-1,61	medium_impact	2,23	damaging	0,58	neutral	0,33	deleterious	3,37	22,9	0,6	0,65	neutral	0,21	disease	0,67	neutral	0,26	neutral	0,44	1	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,73	low_impact	-2,35	medium_impact	-0,21	medium_impact	0,96	0,52	0,9	2,73	6,75	P	0,55	P	0,76	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13341	13341	C	G	MI.21400	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1005	335	F	L	ttC/ttG	7,3	1	0	probably_damaging	1	neutral	0,89	neutral	4,53	neutral	-2,87	deleterious	-5,41	high_impact	5,17	damaging	0,37	damaging	0,12	deleterious	4,41	24,1	0,32	0,5	disease	0,66	disease	0,81	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,73	high_impact	3,52	0,61	0,8	26,87	7,22	P	0,77	P	0,92	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13341	13341	C	A	MI.21401	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1005	335	F	L	ttC/ttA	7,3	1	0	probably_damaging	1	neutral	0,89	neutral	4,53	neutral	-2,87	deleterious	-5,41	high_impact	5,17	damaging	0,37	damaging	0,12	deleterious	4,72	24,6	0,32	0,5	disease	0,66	disease	0,81	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,73	high_impact	3,52	0,61	0,8	26,87	7,22	P	0,77	P	0,92	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13342	13342	A	C	MI.21402	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1006	336	K	Q	Aaa/Caa	-2,34	0	0	probably_damaging	1	neutral	0,3	neutral	4,41	deleterious	-4,66	deleterious	-3,6	high_impact	5,24	damaging	0,47	damaging	0,05	deleterious	3,47	23	0,4	0,5	disease	0,8	disease	0,81	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,03	high_impact	3,58	0,7	0,85	29,19	7,25	P	0,62	P	0,82	disease_causing	0,55	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13342	13342	A	G	MI.21403	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1006	336	K	E	Aaa/Gaa	-2,34	0	0	probably_damaging	1	neutral	0,27	neutral	4,44	deleterious	-4,51	deleterious	-3,6	high_impact	4,89	damaging	0,48	damaging	0,06	deleterious	4,02	23,6	0,32	0,5	disease	0,81	disease	0,82	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,01	high_impact	3,26	0,68	0,85	29,19	7,25	P	0,68	P	0,84	disease_causing	0,67	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13343	13343	A	C	MI.21404	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1007	336	K	T	aAa/aCa	8,44	1	0	probably_damaging	1	neutral	0,43	neutral	4,44	deleterious	-3,45	deleterious	-5,4	high_impact	5,24	damaging	0,46	damaging	0,04	deleterious	3,72	23,3	0,25	0,45	disease	0,81	disease	0,81	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,17	high_impact	3,58	0,56	0,8	29,19	7,25	P	0,68	P	0,75	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13343	13343	A	T	MI.21405	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1007	336	K	M	aAa/aTa	8,44	1	0	probably_damaging	1	neutral	0,24	neutral	4,38	deleterious	-6,16	deleterious	-5,41	high_impact	4,04	damaging	0,5	damaging	0,04	deleterious	4,01	23,6	0,23	0,45	disease	0,89	disease	0,81	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	-0,04	high_impact	2,49	0,55	0,8	29,19	7,25	P	0,53	P	0,4	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13344	13344	A	T	MI.21406	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1008	336	K	N	aaA/aaT	8,44	1	0	probably_damaging	1	neutral	0,32	neutral	4,45	deleterious	-4,19	deleterious	-4,5	high_impact	5,24	damaging	0,43	damaging	0,04	deleterious	3,94	23,6	0,4	0,5	disease	0,86	disease	0,78	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,05	high_impact	3,58	0,63	0,8	29,19	7,25	P	0,75	P	0,63	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13344	13344	A	C	MI.21407	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1008	336	K	N	aaA/aaC	8,44	1	0	probably_damaging	1	neutral	0,32	neutral	4,45	deleterious	-4,19	deleterious	-4,5	high_impact	5,24	damaging	0,43	damaging	0,04	deleterious	3,83	23,4	0,4	0,5	disease	0,86	disease	0,78	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,05	high_impact	3,58	0,63	0,8	29,19	7,25	P	0,75	P	0,63	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13345	13345	G	T	MI.21408	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1009	337	A	S	Gcc/Tcc	2,48	1	0	probably_damaging	1	neutral	0,49	neutral	4,52	neutral	-2,19	deleterious	-2,7	low_impact	1,5	damaging	0,4	damaging	0,07	deleterious	3,73	23,3	0,32	0,5	disease	0,67	disease	0,85	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,85	low_impact	-3,6	medium_impact	0,22	medium_impact	0,17	0,77	0,85	28,19	7,22	P	0,59	P	0,98	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13345	13345	G	C	MI.21409	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1009	337	A	P	Gcc/Ccc	2,48	1	0	probably_damaging	1	neutral	0,24	neutral	4,35	deleterious	-5,4	deleterious	-4,51	high_impact	5,02	damaging	0,43	damaging	0,03	deleterious	3,86	23,5	0,15	0,4	disease	0,89	disease	0,89	disease	0,76	disease	0,84	7	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,04	high_impact	3,38	0,77	0,85	28,19	7,22	P	0,69	P	0,96	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6032	6032	G	C	MI.2141	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	129	43	Q	H	caG/caC	7,07	1	0	probably_damaging	1	neutral	0,09	neutral	2,94	deleterious	-3,74	neutral	-1,67	medium_impact	1,94	neutral	0,62	neutral	0,55	deleterious	2,21	17,6	0,6	0,65	neutral	0,29	disease	0,53	neutral	0,19	neutral	0,44	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,72	low_impact	-3,58	medium_impact	-0,37	medium_impact	0,69	0,68	0,9	2,73	6,75	P	0,57	P	0,7	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13345	13345	G	A	MI.21410	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1009	337	A	T	Gcc/Acc	2,48	1	0	probably_damaging	1	neutral	0,48	neutral	4,46	deleterious	-3,22	deleterious	-3,6	high_impact	4,33	damaging	0,43	damaging	0,02	deleterious	4,36	24,1	0,36	0,5	disease	0,73	disease	0,87	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,21	high_impact	2,75	0,68	0,85	28,19	7,22	P	0,58	P	0,94	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13346	13346	C	G	MI.21411	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1010	337	A	G	gCc/gGc	8,9	1	0	probably_damaging	1	neutral	0,36	neutral	4,38	neutral	-2,27	deleterious	-3,61	medium_impact	3,19	damaging	0,45	damaging	0,06	deleterious	4,03	23,6	0,27	0,45	disease	0,74	disease	0,86	disease	0,64	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,1	medium_impact	1,71	0,77	0,85	28,19	7,22	P	0,55	P	0,82	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13346	13346	C	T	MI.21412	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1010	337	A	V	gCc/gTc	8,9	1	0	probably_damaging	1	neutral	0,53	neutral	4,51	deleterious	-3,59	deleterious	-3,61	high_impact	4,67	damaging	0,4	damaging	0,02	deleterious	4,45	24,2	0,4	0,5	disease	0,83	disease	0,89	disease	0,65	disease	0,74	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,26	high_impact	3,06	0,75	0,85	28,19	7,22	P	0,72	P	0,76	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13346	13346	C	A	MI.21413	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1010	337	A	D	gCc/gAc	8,9	1	0	probably_damaging	1	neutral	0,22	neutral	4,35	deleterious	-5,55	deleterious	-5,41	high_impact	5,02	damaging	0,46	damaging	0,02	deleterious	4,68	24,5	0,12	0,4	disease	0,9	disease	0,93	disease	0,75	disease	0,83	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,07	high_impact	3,38	0,68	0,85	28,19	7,22	P	0,69	P	0,95	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13348	13348	A	T	MI.21414	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1012	338	M	L	Ata/Tta	-16,1	0	0	benign	0,01	neutral	0,84	neutral	4,81	neutral	2,79	deleterious	-2,7	neutral_impact	-0,48	neutral	0,7	neutral	0,68	neutral	1,6	13,88	0,42	0,55	neutral	0,42	disease	0,64	disease	0,63	neutral	0,47	1	neutral	0,12	deleterious	0,92	neutral	-6	neutral	0,22	medium_impact	1,15	medium_impact	0,63	low_impact	-1,64	0,56	0,8	9,78	7,17	N	0,3	N	0,2	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13348	13348	A	C	MI.21415	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1012	338	M	L	Ata/Cta	-16,1	0	0	benign	0,01	neutral	0,84	neutral	4,81	neutral	2,79	deleterious	-2,7	neutral_impact	-0,48	neutral	0,7	neutral	0,68	neutral	1,45	13,06	0,42	0,55	neutral	0,42	disease	0,64	disease	0,63	neutral	0,47	1	neutral	0,12	deleterious	0,92	neutral	-6	neutral	0,22	medium_impact	1,15	medium_impact	0,63	low_impact	-1,64	0,56	0,8	9,78	7,17	N	0,3	N	0,2	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13348	13348	A	G	MI.21416	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1012	338	M	V	Ata/Gta	-16,1	0	0	benign	0,36	neutral	0,54	neutral	4,64	neutral	-0,08	deleterious	-3,6	medium_impact	2,42	neutral	0,61	neutral	0,39	neutral	1,02	10,79	0,51	0,6	neutral	0,49	disease	0,88	disease	0,69	disease	0,74	5	neutral	0,39	deleterious	0,59	neutral	-3	neutral	0,33	medium_impact	-0,51	medium_impact	0,27	medium_impact	1,01	0,56	0,8	9,78	7,17	N	0,26	N	0,76	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13349	13349	T	A	MI.21417	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1013	338	M	K	aTa/aAa	5,46	1	0	possibly_damaging	0,56	neutral	0,33	neutral	4,58	neutral	-2,88	deleterious	-5,41	high_impact	3,87	neutral	0,62	neutral	0,39	deleterious	2,39	18,75	0,19	0,45	disease	0,8	disease	0,95	disease	0,76	disease	0,88	8	neutral	0,67	neutral	0,39	deleterious	1	deleterious	0,65	medium_impact	-0,85	medium_impact	0,06	high_impact	2,33	0,48	0,8	9,78	7,17	P	0,58	P	0,95	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13349	13349	T	C	MI.21418	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1013	338	M	T	aTa/aCa	5,46	1	0	benign	0,04	neutral	0,42	neutral	4,72	neutral	0,3	deleterious	-5,4	low_impact	1,45	damaging	0,58	neutral	0,52	neutral	1,32	12,36	0,37	0,5	neutral	0,48	disease	0,88	disease	0,65	disease	0,68	4	neutral	0,54	deleterious	0,69	neutral	-6	deleterious	0,52	medium_impact	0,57	medium_impact	0,16	medium_impact	0,12	0,39	0,8	9,78	7,17	N	0,45	N	0,92	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13350	13350	A	C	MI.21419	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1014	338	M	I	atA/atC	7,3	1	0	benign	0,25	neutral	0,44	neutral	4,68	neutral	-0,39	deleterious	-3,6	medium_impact	2,71	neutral	0,6	neutral	0,52	neutral	1,58	13,77	0,39	0,5	disease	0,63	disease	0,9	disease	0,67	disease	0,74	5	neutral	0,47	deleterious	0,6	neutral	-3	neutral	0,37	medium_impact	-0,29	medium_impact	0,18	medium_impact	1,27	0,61	0,8	9,78	7,17	P	0,52	P	0,67	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6032	6032	G	T	MI.2142	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	129	43	Q	H	caG/caT	7,07	1	0	probably_damaging	1	neutral	0,09	neutral	2,94	deleterious	-3,74	neutral	-1,67	medium_impact	1,94	neutral	0,62	neutral	0,55	deleterious	2,34	18,4	0,6	0,65	neutral	0,29	disease	0,53	neutral	0,19	neutral	0,44	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,72	low_impact	-3,58	medium_impact	-0,37	medium_impact	0,69	0,68	0,9	2,73	6,75	P	0,56	P	0,7	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13350	13350	A	T	MI.21420	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1014	338	M	I	atA/atT	7,3	1	0	benign	0,25	neutral	0,44	neutral	4,68	neutral	-0,39	deleterious	-3,6	medium_impact	2,71	neutral	0,6	neutral	0,52	neutral	1,65	14,11	0,39	0,5	disease	0,63	disease	0,9	disease	0,67	disease	0,74	5	neutral	0,47	deleterious	0,6	neutral	-3	neutral	0,37	medium_impact	-0,29	medium_impact	0,18	medium_impact	1,27	0,61	0,8	9,78	7,17	P	0,53	P	0,67	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13351	13351	C	A	MI.21421	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1015	339	L	M	Cta/Ata	-0,27	0	0	possibly_damaging	0,76	neutral	0,47	neutral	4,18	deleterious	-4,39	neutral	-1,72	medium_impact	2,56	damaging	0,53	damaging	0,2	deleterious	3,72	23,3	0,27	0,45	disease	0,74	disease	0,66	disease	0,58	disease	0,59	2	neutral	0,75	neutral	0,36	NA	0	deleterious	0,78	low_impact	-1,22	medium_impact	0,2	medium_impact	1,14	0,7	0,85	17,91	7	N	0,32	N	0,89	disease_causing	0,52	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13351	13351	C	G	MI.21422	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1015	339	L	V	Cta/Gta	-0,27	0	0	possibly_damaging	0,9	neutral	0,45	neutral	4,2	deleterious	-4,77	deleterious	-2,66	high_impact	5,13	damaging	0,45	damaging	0,09	deleterious	3,43	23	0,29	0,45	disease	0,81	disease	0,73	disease	0,66	disease	0,71	4	neutral	0,89	neutral	0,28	deleterious	1	deleterious	0,82	low_impact	-1,65	medium_impact	0,18	high_impact	3,48	0,66	0,8	17,91	7	P	0,57	P	0,81	disease_causing	0,57	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13352	13352	T	C	MI.21423	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1016	339	L	P	cTa/cCa	-1,65	0	0	probably_damaging	1	neutral	0,17	neutral	4,06	deleterious	-8	deleterious	-6,23	high_impact	4,58	damaging	0,49	damaging	0,09	deleterious	4,02	23,6	0,14	0,4	disease	0,96	disease	0,83	disease	0,77	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,15	high_impact	2,98	0,65	0,8	17,91	7	N	0,44	N	0,99	disease_causing	1	0,43	.	.	.	.	.	.	COSM1155535	.	.	.	.	.	.	.	.
chrM	13352	13352	T	A	MI.21424	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1016	339	L	Q	cTa/cAa	-1,65	0	0	probably_damaging	0,99	neutral	0,2	neutral	4,06	deleterious	-6,73	deleterious	-5,32	high_impact	4,79	damaging	0,52	damaging	0,09	deleterious	4,28	24	0,18	0,45	disease	0,89	disease	0,87	disease	0,66	disease	0,77	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-2,64	medium_impact	-0,1	high_impact	3,17	0,71	0,85	17,91	7	P	0,55	P	0,98	disease_causing	0,87	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13352	13352	T	G	MI.21425	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1016	339	L	R	cTa/cGa	-1,65	0	0	probably_damaging	0,99	neutral	0,23	neutral	4,07	deleterious	-7,43	deleterious	-5,33	high_impact	5,13	damaging	0,55	damaging	0,08	deleterious	4,18	23,8	0,15	0,45	disease	0,95	disease	0,92	disease	0,77	disease	0,85	7	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,92	low_impact	-2,64	medium_impact	-0,06	high_impact	3,48	0,53	0,8	17,91	7	P	0,61	P	1	disease_causing	0,89	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13354	13354	T	G	MI.21426	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1018	340	F	V	Ttt/Gtt	-2,34	0	0	probably_damaging	1	neutral	0,52	neutral	2,64	deleterious	-7,46	deleterious	-6,31	high_impact	4,2	damaging	0,43	damaging	0,04	deleterious	3,97	23,6	0,2	0,45	disease	0,85	disease	0,89	disease	0,64	disease	0,77	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,25	high_impact	2,63	0,48	0,8	28,19	7,22	N	0,37	N	0,95	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13354	13354	T	C	MI.21427	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1018	340	F	L	Ttt/Ctt	-2,34	0	0	probably_damaging	1	neutral	0,89	neutral	2,74	deleterious	-5,12	deleterious	-5,41	high_impact	4,54	damaging	0,43	damaging	0,03	deleterious	3,99	23,6	0,21	0,45	disease	0,84	disease	0,82	disease	0,65	disease	0,75	5	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,73	high_impact	2,94	0,52	0,8	28,19	7,22	N	0,45	N	0,92	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13354	13354	T	A	MI.21428	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1018	340	F	I	Ttt/Att	-2,34	0	0	probably_damaging	1	neutral	0,44	neutral	2,65	deleterious	-7,21	deleterious	-5,41	high_impact	4,69	damaging	0,43	damaging	0,06	deleterious	4,39	24,1	0,13	0,4	disease	0,89	disease	0,9	disease	0,67	disease	0,79	6	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,18	high_impact	3,08	0,5	0,8	28,19	7,22	P	0,51	P	0,95	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13355	13355	T	A	MI.21429	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1019	340	F	Y	tTt/tAt	5,69	1	0	probably_damaging	1	neutral	0,95	neutral	2,69	deleterious	-5,93	deleterious	-2,7	high_impact	5,24	damaging	0,42	damaging	0,05	deleterious	4,36	24,1	0,16	0,45	disease	0,93	disease	0,84	disease	0,63	disease	0,8	6	deleterious	1	deleterious	0,48	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,94	high_impact	3,58	0,54	0,8	28,19	7,22	P	0,7	P	0,88	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6033	6033	C	G	MI.2143	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	130	44	P	A	Cca/Gca	-1,03	0	0	probably_damaging	1	deleterious	0,02	neutral	2,4	deleterious	-6,63	deleterious	-3,89	medium_impact	2,78	neutral	0,67	damaging	0,07	deleterious	2,88	21,8	0,33	0,55	disease	0,62	disease	0,69	neutral	0,46	disease	0,52	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,81	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,47	0,79	0,9	2,73	6,72	N	0,26	N	0,76	disease_causing	0,9	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13355	13355	T	G	MI.21430	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1019	340	F	C	tTt/tGt	5,69	1	0	probably_damaging	1	neutral	0,19	neutral	2,62	deleterious	-10,27	deleterious	-7,21	high_impact	5,24	damaging	0,48	damaging	0,04	deleterious	4,12	23,8	0,17	0,45	disease	0,97	disease	0,89	disease	0,69	disease	0,82	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,12	high_impact	3,58	0,33	0,8	28,19	7,22	P	0,54	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13355	13355	T	C	MI.21431	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1019	340	F	S	tTt/tCt	5,69	1	0	probably_damaging	1	neutral	0,68	neutral	2,63	deleterious	-9	deleterious	-7,21	high_impact	4,34	damaging	0,45	damaging	0,09	deleterious	4,33	24	0,14	0,4	disease	0,94	disease	0,87	disease	0,66	disease	0,81	6	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,41	high_impact	2,76	0,42	0,8	28,19	7,22	P	0,51	P	0,97	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13356	13356	T	A	MI.21432	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1020	340	F	L	ttT/ttA	7,3	1	0,01	probably_damaging	1	neutral	0,89	neutral	2,74	deleterious	-5,12	deleterious	-5,41	high_impact	4,54	damaging	0,43	damaging	0,03	deleterious	4,5	24,3	0,21	0,45	disease	0,84	disease	0,82	disease	0,65	disease	0,75	5	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,73	high_impact	2,94	0,52	0,8	28,19	7,22	P	0,63	P	0,92	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13356	13356	T	G	MI.21433	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1020	340	F	L	ttT/ttG	7,3	1	0,01	probably_damaging	1	neutral	0,89	neutral	2,74	deleterious	-5,12	deleterious	-5,41	high_impact	4,54	damaging	0,43	damaging	0,03	deleterious	4,39	24,1	0,21	0,45	disease	0,84	disease	0,82	disease	0,65	disease	0,75	5	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,73	high_impact	2,94	0,52	0,8	28,19	7,22	P	0,62	P	0,92	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13357	13357	A	G	MI.21434	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1021	341	M	V	Atg/Gtg	-2,57	0	0	benign	0,12	neutral	0,53	neutral	4,68	neutral	-1,66	deleterious	-2,82	medium_impact	2,95	neutral	0,7	neutral	0,54	deleterious	2,82	21,5	0,44	0,55	disease	0,64	disease	0,73	disease	0,68	disease	0,73	5	neutral	0,38	deleterious	0,71	neutral	-3	deleterious	0,75	medium_impact	0,08	medium_impact	0,26	medium_impact	1,49	0,59	0,8	15,59	13,99	N	0,25	N	0,82	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13357	13357	A	C	MI.21435	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1021	341	M	L	Atg/Ctg	-2,57	0	0	benign	0,01	neutral	0,88	neutral	4,9	neutral	2,24	neutral	-1,41	neutral_impact	-1,03	neutral	0,77	neutral	0,96	deleterious	0,72	8,93	0,4	0,5	neutral	0,38	neutral	0,25	neutral	0,41	neutral	0,4	2	neutral	0,08	deleterious	0,94	neutral	-6	deleterious	0,58	medium_impact	1,15	medium_impact	0,71	low_impact	-2,14	0,66	0,8	15,59	13,99	N	0,32	N	0,46	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13357	13357	A	T	MI.21436	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1021	341	M	L	Atg/Ttg	-2,57	0	0	benign	0,01	neutral	0,88	neutral	4,9	neutral	2,24	neutral	-1,41	neutral_impact	-1,03	neutral	0,77	neutral	0,96	deleterious	0,69	8,77	0,4	0,5	neutral	0,38	neutral	0,25	neutral	0,41	neutral	0,4	2	neutral	0,08	deleterious	0,94	neutral	-6	deleterious	0,58	medium_impact	1,15	medium_impact	0,71	low_impact	-2,14	0,66	0,8	15,59	13,99	N	0,32	N	0,46	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13358	13358	T	A	MI.21437	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1022	341	M	K	aTg/aAg	-1,88	0	0	possibly_damaging	0,7	neutral	0,38	neutral	4,55	deleterious	-4,37	deleterious	-4,89	high_impact	3,85	neutral	0,68	neutral	0,38	deleterious	3,96	23,6	0,16	0,45	disease	0,9	disease	0,87	disease	0,76	disease	0,87	7	neutral	0,73	neutral	0,34	deleterious	1	deleterious	0,88	low_impact	-1,1	medium_impact	0,12	high_impact	2,31	0,5	0,8	15,59	13,99	N	0,4	N	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13358	13358	T	C	MI.21438	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1022	341	M	T	aTg/aCg	-1,88	0	0	possibly_damaging	0,51	neutral	0,46	neutral	4,59	neutral	-2,57	deleterious	-4,63	high_impact	3,85	neutral	0,66	neutral	0,54	deleterious	2,94	22	0,39	0,5	disease	0,79	disease	0,69	disease	0,69	disease	0,77	5	neutral	0,54	deleterious	0,48	deleterious	1	deleterious	0,83	medium_impact	-0,76	medium_impact	0,19	high_impact	2,31	0,46	0,8	15,59	13,99	N	0,34	N	0,91	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13359	13359	G	C	MI.21439	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1023	341	M	I	atG/atC	4,54	0,65	0,01	benign	0,01	neutral	0,44	neutral	4,72	neutral	-1,21	deleterious	-2,56	low_impact	1,43	neutral	0,75	neutral	0,59	deleterious	3,53	23,1	0,41	0,5	disease	0,61	disease	0,77	disease	0,62	disease	0,72	4	neutral	0,55	deleterious	0,72	neutral	-6	deleterious	0,79	medium_impact	1,15	medium_impact	0,18	medium_impact	0,1	0,62	0,8	15,59	13,99	N	0,29	N	0,83	polymorphism	0,93	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6033	6033	C	T	MI.2144	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	130	44	P	S	Cca/Tca	-1,03	0	0	probably_damaging	1	deleterious	0,01	neutral	2,39	deleterious	-6,91	deleterious	-3,95	medium_impact	2,3	damaging	0,58	damaging	0,06	deleterious	3,7	23,3	0,51	0,6	disease	0,56	disease	0,77	neutral	0,42	disease	0,55	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,82	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,03	0,24	0,9	2,73	6,72	N	0,26	N	0,85	disease_causing	0,94	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13359	13359	G	T	MI.21440	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1023	341	M	I	atG/atT	4,54	0,65	0,01	benign	0,01	neutral	0,44	neutral	4,72	neutral	-1,21	deleterious	-2,56	low_impact	1,43	neutral	0,75	neutral	0,59	deleterious	3,66	23,2	0,41	0,5	disease	0,61	disease	0,77	disease	0,62	disease	0,72	4	neutral	0,55	deleterious	0,72	neutral	-6	deleterious	0,79	medium_impact	1,15	medium_impact	0,18	medium_impact	0,1	0,62	0,8	15,59	13,99	N	0,28	N	0,83	polymorphism	0,93	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13360	13360	T	G	MI.21441	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1024	342	C	G	Tgc/Ggc	-0,96	0,02	0	possibly_damaging	0,73	neutral	0,38	neutral	4,65	neutral	0,98	deleterious	-10,01	low_impact	1,82	neutral	0,61	damaging	0,13	deleterious	3,3	22,9	0,36	0,5	neutral	0,38	disease	0,89	disease	0,75	disease	0,63	3	neutral	0,75	neutral	0,33	neutral	-3	deleterious	0,79	low_impact	-1,16	medium_impact	0,12	medium_impact	0,46	0,63	0,8	8,79	12,49	N	0,3	N	0,79	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13360	13360	T	C	MI.21442	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1024	342	C	R	Tgc/Cgc	-0,96	0,02	0	probably_damaging	0,95	neutral	0,34	neutral	4,57	neutral	-2,59	deleterious	-10,11	high_impact	4,61	neutral	0,62	damaging	0,08	deleterious	3,49	23,1	0,31	0,45	disease	0,74	disease	0,96	disease	0,84	disease	0,92	8	neutral	0,96	neutral	0,2	deleterious	2	deleterious	0,92	low_impact	-1,96	medium_impact	0,07	high_impact	3,01	0,37	0,8	8,79	12,49	P	0,57	P	0,89	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13360	13360	T	A	MI.21443	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1024	342	C	S	Tgc/Agc	-0,96	0,02	0	benign	0,12	neutral	0,51	neutral	4,59	neutral	0,23	deleterious	-8,14	low_impact	1,29	neutral	0,67	neutral	0,71	deleterious	3,45	23	0,39	0,5	neutral	0,5	disease	0,82	disease	0,7	disease	0,56	1	neutral	0,4	deleterious	0,7	neutral	-6	deleterious	0,81	medium_impact	0,08	medium_impact	0,24	medium_impact	-0,02	0,75	0,85	8,79	12,49	N	0,31	N	0,45	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13361	13361	G	C	MI.21444	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1025	342	C	S	tGc/tCc	7,3	1	0	benign	0,12	neutral	0,51	neutral	4,59	neutral	0,23	deleterious	-8,14	low_impact	1,29	neutral	0,67	neutral	0,71	deleterious	3,13	22,6	0,39	0,5	neutral	0,5	disease	0,82	disease	0,7	disease	0,56	1	neutral	0,4	deleterious	0,7	neutral	-6	deleterious	0,81	medium_impact	0,08	medium_impact	0,24	medium_impact	-0,02	0,75	0,85	8,79	12,49	N	0,49	N	0,45	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13361	13361	G	A	MI.21445	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1025	342	C	Y	tGc/tAc	7,3	1	0	probably_damaging	0,98	neutral	1	neutral	4,57	deleterious	-3,04	deleterious	-9,32	high_impact	4,61	neutral	0,62	damaging	0,07	deleterious	3,63	23,2	0,28	0,45	disease	0,79	disease	0,95	disease	0,78	disease	0,89	8	neutral	0,98	deleterious	0,51	deleterious	2	deleterious	0,89	low_impact	-2,35	high_impact	1,89	high_impact	3,01	0,67	0,85	8,79	12,49	P	0,55	P	0,94	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13361	13361	G	T	MI.21446	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1025	342	C	F	tGc/tTc	7,3	1	0	probably_damaging	0,98	neutral	0,78	neutral	4,65	neutral	-1,82	deleterious	-9,32	high_impact	4,05	neutral	0,61	damaging	0,1	deleterious	3,98	23,6	0,26	0,45	disease	0,79	disease	0,96	disease	0,77	disease	0,88	8	neutral	0,97	neutral	0,4	deleterious	2	deleterious	0,9	low_impact	-2,35	medium_impact	0,54	high_impact	2,5	0,66	0,8	8,79	12,49	N	0,5	N	0,95	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13362	13362	C	A	MI.21447	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1026	342	C	W	tgC/tgA	5,92	1	0	probably_damaging	0,99	neutral	0,18	neutral	4,55	deleterious	-4,57	deleterious	-9,37	high_impact	4,61	neutral	0,64	damaging	0,08	deleterious	4,59	24,4	0,2	0,45	disease	0,93	disease	0,94	disease	0,82	disease	0,87	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-2,64	medium_impact	-0,13	high_impact	3,01	0,42	0,8	8,79	12,49	P	0,59	P	0,96	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13362	13362	C	G	MI.21448	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1026	342	C	W	tgC/tgG	5,92	1	0	probably_damaging	0,99	neutral	0,18	neutral	4,55	deleterious	-4,57	deleterious	-9,37	high_impact	4,61	neutral	0,64	damaging	0,08	deleterious	4,34	24	0,2	0,45	disease	0,93	disease	0,94	disease	0,82	disease	0,87	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-2,64	medium_impact	-0,13	high_impact	3,01	0,42	0,8	8,79	12,49	P	0,58	P	0,96	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13363	13363	T	G	MI.21449	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1027	343	S	A	Tcc/Gcc	-0,27	0,35	0	benign	0,07	neutral	0,53	neutral	4,87	neutral	1,93	neutral	-2,26	neutral_impact	-0,2	neutral	0,71	neutral	0,46	deleterious	2,65	20,5	0,4	0,5	neutral	0,34	neutral	0,31	disease	0,52	neutral	0,41	2	neutral	0,41	deleterious	0,73	neutral	-6	deleterious	0,69	medium_impact	0,32	medium_impact	0,26	low_impact	-1,39	0,79	0,85	8,13	14,51	N	0,3	N	0,49	disease_causing	0,98	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6033	6033	C	A	MI.2145	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	130	44	P	T	Cca/Aca	-1,03	0	0	probably_damaging	1	neutral	0,06	neutral	2,36	deleterious	-7,35	deleterious	-3,9	medium_impact	3,01	neutral	0,68	damaging	0,05	deleterious	3,64	23,2	0,39	0,55	disease	0,73	disease	0,8	neutral	0,41	disease	0,58	2	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,83	low_impact	-3,58	medium_impact	-0,47	medium_impact	1,68	0,71	0,9	2,73	6,72	N	0,27	N	0,8	disease_causing	0,94	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13363	13363	T	A	MI.21450	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1027	343	S	T	Tcc/Acc	-0,27	0,35	0	possibly_damaging	0,7	neutral	0,39	neutral	4,6	neutral	-1,63	deleterious	-2,56	medium_impact	2,67	neutral	0,63	damaging	0,08	deleterious	3,84	23,4	0,35	0,5	disease	0,6	disease	0,77	disease	0,64	disease	0,67	3	neutral	0,72	neutral	0,35	NA	0	deleterious	0,81	low_impact	-1,1	medium_impact	0,13	medium_impact	1,24	0,87	0,9	8,13	14,51	N	0,21	N	0,71	disease_causing	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13363	13363	T	C	MI.21451	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1027	343	S	P	Tcc/Ccc	-0,27	0,35	0	probably_damaging	0,92	neutral	0,2	neutral	4,56	deleterious	-4,71	deleterious	-4,29	high_impact	4,21	neutral	0,63	damaging	0,08	deleterious	4	23,6	0,2	0,45	disease	0,91	disease	0,89	disease	0,81	disease	0,86	7	neutral	0,95	neutral	0,14	deleterious	2	deleterious	0,89	low_impact	-1,75	medium_impact	-0,1	high_impact	2,64	0,79	0,85	8,13	14,51	N	0,44	N	0,98	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13364	13364	C	A	MI.21452	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1028	343	S	Y	tCc/tAc	3,63	1	0	probably_damaging	0,98	neutral	1	neutral	4,58	deleterious	-3,66	deleterious	-5,19	high_impact	4,21	neutral	0,62	damaging	0,08	deleterious	4,09	23,7	0,16	0,45	disease	0,84	disease	0,9	disease	0,74	disease	0,82	6	neutral	0,98	deleterious	0,51	deleterious	2	deleterious	0,86	low_impact	-2,35	high_impact	1,89	high_impact	2,64	0,75	0,85	8,13	14,51	N	0,41	N	0,99	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13364	13364	C	G	MI.21453	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1028	343	S	C	tCc/tGc	3,63	1	0	probably_damaging	0,98	neutral	0,19	neutral	4,56	deleterious	-3,64	deleterious	-4,21	medium_impact	3,17	neutral	0,63	damaging	0,08	deleterious	3,61	23,2	0,2	0,45	disease	0,9	disease	0,86	disease	0,64	disease	0,79	6	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,82	low_impact	-2,35	medium_impact	-0,12	medium_impact	1,69	0,74	0,85	8,13	14,51	N	0,38	N	0,99	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13364	13364	C	T	MI.21454	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1028	343	S	F	tCc/tTc	3,63	1	0	probably_damaging	0,98	neutral	0,71	neutral	4,63	neutral	-2,38	deleterious	-5,19	high_impact	4,21	damaging	0,59	damaging	0,06	deleterious	4,28	24	0,17	0,45	disease	0,72	disease	0,91	disease	0,72	disease	0,79	6	neutral	0,97	neutral	0,37	deleterious	2	deleterious	0,86	low_impact	-2,35	medium_impact	0,45	high_impact	2,64	0,55	0,8	8,13	14,51	N	0,4	N	0,99	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13366	13366	G	T	MI.21455	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1030	344	G	W	Ggg/Tgg	-20	0	0	probably_damaging	1	neutral	0,18	neutral	4,32	deleterious	-8,23	deleterious	-7,21	high_impact	5,24	neutral	0,6	damaging	0,06	deleterious	4,46	24,2	0,1	0,4	disease	0,98	disease	0,89	disease	0,79	disease	0,88	8	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,13	high_impact	3,58	0,38	0,8	30,18	7,15	N	0,5	N	1	disease_causing	0,79	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13366	13366	G	C	MI.21456	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1030	344	G	R	Ggg/Cgg	-20	0	0	probably_damaging	1	neutral	0,35	neutral	4,38	deleterious	-6,65	deleterious	-7,21	high_impact	5,24	damaging	0,6	damaging	0,06	deleterious	4,04	23,7	0,09	0,35	disease	0,91	disease	0,9	disease	0,83	disease	0,85	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,93	low_impact	-3,6	medium_impact	0,08	high_impact	3,58	0,69	0,85	30,18	7,15	P	0,59	P	1	disease_causing	0,7	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13367	13367	G	C	MI.21457	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1031	344	G	A	gGg/gCg	8,9	1	0	probably_damaging	1	neutral	0,51	neutral	4,42	deleterious	-4,77	deleterious	-5,4	high_impact	4,34	damaging	0,56	damaging	0,12	deleterious	3,21	22,7	0,19	0,45	disease	0,79	disease	0,73	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,24	high_impact	2,76	0,65	0,8	30,18	7,15	P	0,52	P	0,79	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13367	13367	G	A	MI.21458	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1031	344	G	E	gGg/gAg	8,9	1	0	probably_damaging	1	neutral	0,27	neutral	4,45	deleterious	-6,67	deleterious	-7,21	high_impact	5,24	damaging	0,56	damaging	0,06	deleterious	3,92	23,5	0,12	0,4	disease	0,91	disease	0,89	disease	0,82	disease	0,85	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,01	high_impact	3,58	0,59	0,8	30,18	7,15	P	0,71	P	1	disease_causing	1	0,42	.	.	.	.	.	.	COSM1155536	.	.	.	.	.	.	.	.
chrM	13367	13367	G	T	MI.21459	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1031	344	G	V	gGg/gTg	8,9	1	0	probably_damaging	1	neutral	0,5	neutral	4,37	deleterious	-5,18	deleterious	-8,11	high_impact	5,24	damaging	0,42	damaging	0,06	deleterious	3,85	23,4	0,11	0,4	disease	0,86	disease	0,89	disease	0,75	disease	0,83	7	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,23	high_impact	3,58	0,52	0,8	30,18	7,15	P	0,67	P	0,98	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6034	6034	C	G	MI.2146	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	131	44	P	R	cCa/cGa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,35	deleterious	-7,9	deleterious	-4,69	high_impact	3,86	neutral	0,67	damaging	0,03	deleterious	3,43	23	0,3	0,55	disease	0,89	disease	0,9	disease	0,74	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	2,47	0,64	0,9	2,73	6,72	N	0,46	N	0,9	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13369	13369	T	G	MI.21460	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1033	345	S	A	Tcc/Gcc	-12,2	0	0	probably_damaging	1	neutral	0,54	neutral	4,57	neutral	-0,16	deleterious	-2,55	low_impact	1,25	neutral	0,72	neutral	0,42	deleterious	3,7	23,3	0,49	0,55	neutral	0,4	disease	0,57	neutral	0,5	neutral	0,44	1	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,27	medium_impact	-0,06	0,77	0,85	21,23	7,05	N	0,28	N	0,49	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13369	13369	T	A	MI.21461	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1033	345	S	T	Tcc/Acc	-12,2	0	0	probably_damaging	1	neutral	0,41	neutral	4,56	neutral	-2,08	deleterious	-2,65	medium_impact	2,42	damaging	0,6	damaging	0,17	deleterious	3,83	23,4	0,39	0,5	disease	0,66	disease	0,77	disease	0,62	disease	0,57	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,15	medium_impact	1,01	0,77	0,85	21,23	7,05	N	0,23	N	0,71	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13369	13369	T	C	MI.21462	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1033	345	S	P	Tcc/Ccc	-12,2	0	0	probably_damaging	1	neutral	0,22	neutral	4,46	deleterious	-5,23	deleterious	-4,43	high_impact	3,88	neutral	0,63	damaging	0,11	deleterious	3,99	23,6	0,19	0,45	disease	0,9	disease	0,89	disease	0,8	disease	0,86	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,07	high_impact	2,34	0,61	0,8	21,23	7,05	N	0,36	N	0,98	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13370	13370	C	T	MI.21463	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1034	345	S	F	tCc/tTc	2,71	0,88	0	probably_damaging	1	neutral	0,72	neutral	4,51	deleterious	-3,01	deleterious	-5,33	medium_impact	2,4	neutral	0,63	damaging	0,09	deleterious	4,28	24	0,19	0,45	disease	0,74	disease	0,9	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	0,46	medium_impact	0,99	0,43	0,8	21,23	7,05	N	0,23	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13370	13370	C	G	MI.21464	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1034	345	S	C	tCc/tGc	2,71	0,88	0	probably_damaging	1	neutral	0,2	neutral	4,48	deleterious	-4,27	deleterious	-4,4	medium_impact	2,95	neutral	0,65	damaging	0,1	deleterious	3,56	23,1	0,23	0,45	disease	0,77	disease	0,85	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,1	medium_impact	1,49	0,66	0,8	21,23	7,05	N	0,3	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13370	13370	C	A	MI.21465	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1034	345	S	Y	tCc/tAc	2,71	0,88	0	probably_damaging	1	neutral	1	neutral	4,49	deleterious	-3,28	deleterious	-5,33	medium_impact	2,58	neutral	0,64	damaging	0,08	deleterious	4,03	23,7	0,18	0,45	disease	0,71	disease	0,9	disease	0,71	disease	0,78	6	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,85	low_impact	-3,6	high_impact	1,89	medium_impact	1,15	0,75	0,85	21,23	7,05	N	0,22	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13372	13372	A	C	MI.21466	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1036	346	I	L	Atc/Ctc	-8,53	0	0	possibly_damaging	0,49	neutral	0,66	neutral	4,55	neutral	-0,71	neutral	-1,79	low_impact	1,5	neutral	0,75	neutral	0,66	deleterious	3,83	23,4	0,42	0,55	neutral	0,49	disease	0,64	disease	0,61	neutral	0,49	0	neutral	0,41	deleterious	0,59	neutral	-3	deleterious	0,71	medium_impact	-0,73	medium_impact	0,39	medium_impact	0,17	0,81	0,85	18,24	7,26	N	0,24	N	0,66	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13372	13372	A	T	MI.21467	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1036	346	I	F	Atc/Ttc	-8,53	0	0	probably_damaging	0,94	neutral	0,71	neutral	4,48	neutral	-2,92	deleterious	-3,58	low_impact	1,13	neutral	0,77	neutral	0,7	deleterious	3,89	23,5	0,29	0,45	disease	0,77	disease	0,77	disease	0,67	disease	0,6	2	neutral	0,93	neutral	0,39	neutral	-2	deleterious	0,81	low_impact	-1,88	medium_impact	0,45	medium_impact	-0,17	0,81	0,85	18,24	7,26	N	0,19	N	0,95	polymorphism	0,65	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13372	13372	A	G	MI.21468	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1036	346	I	V	Atc/Gtc	-8,53	0	0	possibly_damaging	0,62	neutral	0,51	neutral	4,59	neutral	0,63	neutral	-0,89	neutral_impact	0,63	neutral	0,83	neutral	0,89	deleterious	3,02	22,3	0,57	0,65	neutral	0,33	neutral	0,25	disease	0,53	neutral	0,42	2	neutral	0,6	neutral	0,45	neutral	-3	deleterious	0,64	medium_impact	-0,95	medium_impact	0,24	medium_impact	-0,63	0,61	0,8	18,24	7,26	N	0,33	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13373	13373	T	C	MI.21469	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1037	346	I	T	aTc/aCc	3,83	0,99	0	probably_damaging	0,94	neutral	0,41	neutral	4,43	deleterious	-3,15	deleterious	-4,46	medium_impact	3,45	neutral	0,73	neutral	0,43	deleterious	3,45	23	0,36	0,5	disease	0,78	disease	0,82	disease	0,69	disease	0,7	4	neutral	0,93	neutral	0,24	deleterious	1	deleterious	0,84	low_impact	-1,88	medium_impact	0,15	medium_impact	1,95	0,7	0,85	18,24	7,26	N	0,44	N	0,96	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6034	6034	C	A	MI.2147	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	131	44	P	Q	cCa/cAa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,37	deleterious	-8,2	deleterious	-4,13	high_impact	4,9	neutral	0,67	damaging	0,03	deleterious	3,88	23,5	0,26	0,55	disease	0,89	disease	0,87	disease	0,69	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,43	0,64	0,9	2,73	6,72	P	0,68	P	0,82	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13373	13373	T	A	MI.21470	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1037	346	I	N	aTc/aAc	3,83	0,99	0	probably_damaging	0,98	neutral	0,33	neutral	4,41	deleterious	-5,14	deleterious	-6,25	high_impact	4,34	neutral	0,71	neutral	0,38	deleterious	4,45	24,2	0,25	0,45	disease	0,92	disease	0,85	disease	0,72	disease	0,83	7	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-2,35	medium_impact	0,06	high_impact	2,76	0,77	0,85	18,24	7,26	P	0,51	P	0,98	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13373	13373	T	G	MI.21471	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1037	346	I	S	aTc/aGc	3,83	0,99	0	probably_damaging	0,94	neutral	0,44	neutral	4,45	deleterious	-3,78	deleterious	-5,34	medium_impact	3,45	neutral	0,75	neutral	0,44	deleterious	4,32	24	0,25	0,45	disease	0,74	disease	0,87	disease	0,69	disease	0,73	5	neutral	0,93	neutral	0,25	deleterious	1	deleterious	0,85	low_impact	-1,88	medium_impact	0,18	medium_impact	1,95	0,63	0,8	18,24	7,26	N	0,47	N	0,96	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13374	13374	C	G	MI.21472	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1038	346	I	M	atC/atG	7,27	1	0	possibly_damaging	0,61	neutral	0,22	neutral	4,45	deleterious	-3,16	deleterious	-2,68	medium_impact	1,98	neutral	0,81	neutral	0,58	deleterious	3,36	22,9	0,39	0,5	disease	0,8	disease	0,66	disease	0,63	disease	0,64	3	neutral	0,79	neutral	0,31	NA	0	deleterious	0,78	medium_impact	-0,93	medium_impact	-0,07	medium_impact	0,61	0,85	0,9	18,24	7,26	N	0,51	P	0,76	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13374	13374	C	A	MI.21473	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1038	346	I	M	atC/atA	7,27	1	0	possibly_damaging	0,61	neutral	0,22	neutral	4,45	deleterious	-3,16	deleterious	-2,68	medium_impact	1,98	neutral	0,81	neutral	0,58	deleterious	3,88	23,5	0,39	0,5	disease	0,8	disease	0,66	disease	0,63	disease	0,64	3	neutral	0,79	neutral	0,31	NA	0	deleterious	0,78	medium_impact	-0,93	medium_impact	-0,07	medium_impact	0,61	0,85	0,9	18,24	7,26	N	0,51	P	0,76	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13375	13375	A	G	MI.21474	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1039	347	I	V	Atc/Gtc	-4,19	0	0	probably_damaging	1	neutral	0,54	neutral	4,42	neutral	-1,93	neutral	-0,9	high_impact	3,94	damaging	0,33	neutral	0,42	deleterious	3,1	22,5	0,58	0,65	disease	0,57	disease	0,52	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,71	low_impact	-3,6	medium_impact	0,27	high_impact	2,4	0,7	0,85	28,03	7,24	P	0,62	P	0,74	disease_causing	0,98	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13375	13375	A	T	MI.21475	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1039	347	I	F	Atc/Ttc	-4,19	0	0	probably_damaging	1	neutral	0,76	neutral	4,34	deleterious	-4,16	deleterious	-3,6	high_impact	5,03	damaging	0,37	neutral	0,39	deleterious	3,8	23,4	0,37	0,5	disease	0,88	disease	0,82	disease	0,76	disease	0,82	6	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,51	high_impact	3,39	0,84	0,9	28,03	7,24	P	0,76	P	0,96	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13375	13375	A	C	MI.21476	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1039	347	I	L	Atc/Ctc	-4,19	0	0	probably_damaging	1	neutral	0,94	neutral	4,41	neutral	-1,83	neutral	-1,8	medium_impact	3,4	damaging	0,35	neutral	0,46	deleterious	3,83	23,4	0,36	0,5	disease	0,69	disease	0,67	disease	0,7	disease	0,71	4	deleterious	1	deleterious	0,47	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,89	medium_impact	1,9	0,75	0,85	28,03	7,24	P	0,59	P	0,86	disease_causing	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13376	13376	T	A	MI.21477	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1040	347	I	N	aTc/aAc	8,42	1	0	probably_damaging	1	neutral	0,41	neutral	4,3	deleterious	-5,45	deleterious	-6,31	high_impact	4,68	damaging	0,37	neutral	0,46	deleterious	4,5	24,3	0,29	0,45	disease	0,87	disease	0,83	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,15	high_impact	3,07	0,73	0,85	28,03	7,24	P	0,76	P	0,99	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13376	13376	T	C	MI.21478	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1040	347	I	T	aTc/aCc	8,42	1	0	probably_damaging	1	neutral	0,43	neutral	4,34	deleterious	-3,76	deleterious	-4,5	high_impact	4,48	damaging	0,41	neutral	0,43	deleterious	3,47	23	0,43	0,55	disease	0,77	disease	0,83	disease	0,74	disease	0,77	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,17	high_impact	2,89	0,77	0,85	28,03	7,24	P	0,74	P	0,96	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13376	13376	T	G	MI.21479	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1040	347	I	S	aTc/aGc	8,42	1	0	probably_damaging	1	neutral	0,56	neutral	4,37	deleterious	-3,88	deleterious	-5,4	high_impact	3,79	damaging	0,45	neutral	0,51	deleterious	4,33	24	0,32	0,5	disease	0,76	disease	0,86	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,29	high_impact	2,26	0,66	0,8	28,03	7,24	P	0,63	P	0,96	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6034	6034	C	T	MI.2148	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	131	44	P	L	cCa/cTa	7,3	1	0	probably_damaging	1	deleterious	0,01	neutral	2,34	deleterious	-7,75	deleterious	-5,05	high_impact	3,58	neutral	0,69	damaging	0,02	deleterious	4,26	23,9	0,41	0,55	disease	0,89	disease	0,88	disease	0,65	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,58	medium_impact	-0,92	high_impact	2,21	0,73	0,9	2,73	6,72	N	0,48	N	0,87	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13377	13377	C	G	MI.21480	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1041	347	I	M	atC/atG	5,67	1	0	probably_damaging	1	neutral	0,28	neutral	4,32	deleterious	-3,2	deleterious	-2,7	medium_impact	3,21	damaging	0,45	neutral	0,52	deleterious	3,44	23	0,52	0,6	disease	0,84	disease	0,71	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,01	medium_impact	1,73	0,89	0,9	28,03	7,24	P	0,61	P	0,76	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13377	13377	C	A	MI.21481	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1041	347	I	M	atC/atA	5,67	1	0	probably_damaging	1	neutral	0,28	neutral	4,32	deleterious	-3,2	deleterious	-2,7	medium_impact	3,21	damaging	0,45	neutral	0,52	deleterious	3,88	23,5	0,52	0,6	disease	0,84	disease	0,71	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,01	medium_impact	1,73	0,89	0,9	28,03	7,24	P	0,61	P	0,76	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13378	13378	C	G	MI.21482	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1042	348	H	D	Cac/Gac	-4,19	0	0	probably_damaging	1	neutral	0,22	neutral	4,61	neutral	-2,82	deleterious	-8,11	high_impact	4,42	damaging	0,5	damaging	0,1	deleterious	3,94	23,5	0,16	0,45	disease	0,6	disease	0,88	disease	0,85	disease	0,82	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,07	high_impact	2,83	0,49	0,8	28,52	7,26	P	0,55	P	0,97	disease_causing	0,61	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13378	13378	C	A	MI.21483	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1042	348	H	N	Cac/Aac	-4,19	0	0	probably_damaging	1	neutral	0,42	neutral	4,55	deleterious	-3,61	deleterious	-6,31	high_impact	4,14	damaging	0,36	damaging	0,1	deleterious	3,95	23,6	0,42	0,55	disease	0,73	disease	0,86	disease	0,8	disease	0,78	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,16	high_impact	2,58	0,45	0,8	28,52	7,26	P	0,54	P	0,97	polymorphism	0,68	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13378	13378	C	T	MI.21484	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1042	348	H	Y	Cac/Tac	-4,19	0	0	probably_damaging	1	neutral	1	neutral	4,55	neutral	-1,69	deleterious	-5,41	high_impact	3,62	damaging	0,43	damaging	0,09	deleterious	3,77	23,4	0,47	0,55	disease	0,78	disease	0,9	disease	0,76	disease	0,79	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,87	low_impact	-3,6	high_impact	1,89	high_impact	2,1	0,51	0,8	28,52	7,26	N	0,37	N	1	polymorphism	0,63	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13379	13379	A	T	MI.21485	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1043	348	H	L	cAc/cTc	5,44	1	0	probably_damaging	1	neutral	0,78	neutral	4,55	neutral	-2,84	deleterious	-9,91	high_impact	3,54	damaging	0,35	damaging	0,09	deleterious	3,96	23,6	0,17	0,45	disease	0,68	disease	0,92	disease	0,8	disease	0,82	6	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,54	high_impact	2,03	0,35	0,8	28,52	7,26	P	0,67	P	0,97	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13379	13379	A	G	MI.21486	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1043	348	H	R	cAc/cGc	5,44	1	0	probably_damaging	1	neutral	0,35	neutral	4,54	neutral	-2,63	deleterious	-7,21	high_impact	3,8	damaging	0,48	damaging	0,1	deleterious	3,05	22,4	0,39	0,5	disease	0,69	disease	0,89	disease	0,82	disease	0,82	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,08	high_impact	2,27	0,54	0,8	28,52	7,26	P	0,56	P	0,99	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13379	13379	A	C	MI.21487	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1043	348	H	P	cAc/cCc	5,44	1	0	probably_damaging	1	neutral	0,21	neutral	4,49	deleterious	-4,94	deleterious	-9,01	high_impact	4,57	damaging	0,41	damaging	0,11	deleterious	3,28	22,8	0,15	0,4	disease	0,86	disease	0,92	disease	0,87	disease	0,85	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,09	high_impact	2,97	0,28	0,8	28,52	7,26	P	0,8	P	0,97	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	A13379C	LHON	+	-	Reported	1
chrM	13380	13380	C	G	MI.21488	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1044	348	H	Q	caC/caG	8,42	1	0	probably_damaging	1	neutral	0,31	neutral	4,56	neutral	-2,84	deleterious	-7,21	high_impact	4,42	damaging	0,44	damaging	0,11	deleterious	3,6	23,2	0,49	0,55	disease	0,71	disease	0,87	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,04	high_impact	2,83	0,64	0,8	28,52	7,26	P	0,7	P	0,95	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13380	13380	C	A	MI.21489	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1044	348	H	Q	caC/caA	8,42	1	0	probably_damaging	1	neutral	0,31	neutral	4,56	neutral	-2,84	deleterious	-7,21	high_impact	4,42	damaging	0,44	damaging	0,11	deleterious	3,97	23,6	0,49	0,55	disease	0,71	disease	0,87	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,04	high_impact	2,83	0,64	0,8	28,52	7,26	P	0,71	P	0,95	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6036	6036	G	T	MI.2149	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	133	45	G	C	Ggc/Tgc	-14,91	0	0	probably_damaging	1	deleterious	0	neutral	2,65	deleterious	-5,66	deleterious	-5,31	high_impact	4,96	damaging	0,42	damaging	0,02	deleterious	4,04	23,7	0,22	0,55	disease	0,96	disease	0,93	disease	0,65	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,41	0,9	3,9	6,63	N	0,5	N	0,98	polymorphism	0,72	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13381	13381	A	T	MI.21490	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1045	349	N	Y	Aac/Tac	-2,58	0	0	probably_damaging	0,99	neutral	1	neutral	4,46	deleterious	-3,58	deleterious	-5,1	low_impact	1,93	neutral	0,76	neutral	0,57	deleterious	3,61	23,2	0,54	0,6	disease	0,85	disease	0,79	disease	0,65	disease	0,78	6	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,84	low_impact	-2,64	high_impact	1,89	medium_impact	0,56	0,44	0,8	2,82	9,78	N	0,18	N	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13381	13381	A	G	MI.21491	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1045	349	N	D	Aac/Gac	-2,58	0	0	possibly_damaging	0,86	neutral	0,25	neutral	4,49	neutral	-1,92	deleterious	-2,82	medium_impact	2,34	neutral	0,72	neutral	0,52	deleterious	3,8	23,4	0,77	0,8	disease	0,6	disease	0,66	disease	0,67	disease	0,71	4	neutral	0,9	neutral	0,2	NA	0	deleterious	0,78	low_impact	-1,5	medium_impact	-0,03	medium_impact	0,94	0,57	0,8	2,82	9,78	N	0,3	N	0,63	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13381	13381	A	C	MI.21492	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1045	349	N	H	Aac/Cac	-2,58	0	0	probably_damaging	0,99	neutral	0,57	neutral	4,47	neutral	-2,92	deleterious	-3,24	medium_impact	3	neutral	0,82	neutral	0,57	deleterious	3,07	22,4	0,64	0,7	disease	0,77	disease	0,65	disease	0,7	disease	0,75	5	deleterious	0,99	neutral	0,29	deleterious	1	deleterious	0,8	low_impact	-2,64	medium_impact	0,3	medium_impact	1,54	0,53	0,8	2,82	9,78	N	0,21	N	0,56	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13382	13382	A	G	MI.21493	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1046	349	N	S	aAc/aGc	6,81	0,82	0	benign	0,18	neutral	0,51	neutral	4,55	neutral	-0,88	neutral	-1,13	neutral_impact	-0,1	neutral	0,83	neutral	0,99	neutral	0,95	10,36	0,73	0,75	neutral	0,31	neutral	0,13	neutral	0,24	neutral	0,25	5	neutral	0,39	deleterious	0,67	neutral	-6	deleterious	0,68	medium_impact	-0,12	medium_impact	0,24	low_impact	-1,29	0,25	0,8	2,82	9,78	N	0,5	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13382	13382	A	C	MI.21494	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1046	349	N	T	aAc/aCc	6,81	0,82	0	possibly_damaging	0,81	neutral	0,42	neutral	4,5	neutral	-1,78	deleterious	-2,87	low_impact	1,73	neutral	0,78	neutral	0,79	deleterious	3,9	23,5	0,58	0,65	disease	0,57	disease	0,68	disease	0,59	disease	0,66	3	neutral	0,81	neutral	0,31	neutral	-3	deleterious	0,77	low_impact	-1,34	medium_impact	0,16	medium_impact	0,38	0,5	0,8	2,82	9,78	N	0,4	N	0,34	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13382	13382	A	T	MI.21495	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1046	349	N	I	aAc/aTc	6,81	0,82	0	probably_damaging	0,98	neutral	0,43	neutral	4,48	neutral	-2,2	deleterious	-5,58	medium_impact	2,49	neutral	0,76	neutral	0,61	deleterious	4,48	24,2	0,56	0,6	disease	0,62	disease	0,82	disease	0,6	disease	0,75	5	neutral	0,98	neutral	0,23	deleterious	1	deleterious	0,81	low_impact	-2,35	medium_impact	0,17	medium_impact	1,07	0,32	0,8	2,82	9,78	N	0,39	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13383	13383	C	G	MI.21496	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1047	349	N	K	aaC/aaG	-0,75	0	0	possibly_damaging	0,88	neutral	0,34	neutral	4,55	neutral	-0,86	deleterious	-3,3	medium_impact	2,25	neutral	0,74	neutral	0,6	deleterious	4,08	23,7	0,76	0,8	neutral	0,42	disease	0,79	disease	0,72	disease	0,76	5	neutral	0,89	neutral	0,23	NA	0	deleterious	0,78	low_impact	-1,57	medium_impact	0,07	medium_impact	0,85	0,57	0,8	2,82	9,78	N	0,32	N	0,69	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13383	13383	C	A	MI.21497	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1047	349	N	K	aaC/aaA	-0,75	0	0	possibly_damaging	0,88	neutral	0,34	neutral	4,55	neutral	-0,86	deleterious	-3,3	medium_impact	2,25	neutral	0,74	neutral	0,6	deleterious	4,55	24,4	0,76	0,8	neutral	0,42	disease	0,79	disease	0,72	disease	0,76	5	neutral	0,89	neutral	0,23	NA	0	deleterious	0,78	low_impact	-1,57	medium_impact	0,07	medium_impact	0,85	0,57	0,8	2,82	9,78	N	0,31	N	0,69	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13384	13384	C	A	MI.21498	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1048	350	L	I	Ctt/Att	-0,29	0	0	probably_damaging	1	neutral	0,42	neutral	4,62	neutral	-1,24	neutral	-1,8	medium_impact	2,4	damaging	0,58	damaging	0,08	deleterious	4,34	24	0,6	0,65	NA	NA	disease	0,78	disease	0,52	disease	0,6	2	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,16	medium_impact	0,99	0,62	0,8	23,05	7,06	N	0,23	N	0,85	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13384	13384	C	G	MI.21499	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1048	350	L	V	Ctt/Gtt	-0,29	0	0	probably_damaging	1	neutral	0,53	neutral	4,64	neutral	-0,21	deleterious	-2,7	low_impact	1,84	damaging	0,56	damaging	0,09	deleterious	3,5	23,1	0,63	0,65	NA	NA	disease	0,67	disease	0,65	disease	0,5	0	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,84	low_impact	-3,6	medium_impact	0,26	medium_impact	0,48	0,43	0,8	23,05	7,06	N	0,18	N	0,81	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8627	8627	C	A	MI.215	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	101	34	S	Y	tCc/tAc	0,59	0	0	probably_damaging	1	neutral	0,96	neutral	4,28	neutral	-2,08	deleterious	-3,56	low_impact	1,69	neutral	0,86	damaging	0,17	deleterious	3,92	23,5	0,38	0,65	disease	0,77	disease	0,71	disease	0,63	disease	0,73	5	deleterious	1	deleterious	0,48	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	1,07	medium_impact	0,35	0,52	0,9	9,73	14,65	N	0,17	N	0,9	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6036	6036	G	A	MI.2150	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	133	45	G	S	Ggc/Agc	-14,91	0	0	probably_damaging	1	neutral	0,09	neutral	2,79	neutral	-1,35	deleterious	-3,4	medium_impact	2,55	damaging	0,49	damaging	0,05	deleterious	4,01	23,6	0,31	0,55	disease	0,56	disease	0,85	disease	0,54	disease	0,52	0	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,84	low_impact	-3,58	medium_impact	-0,37	medium_impact	1,26	0,65	0,9	3,9	6,63	N	0,27	N	0,73	polymorphism	0,91	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13384	13384	C	T	MI.21500	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1048	350	L	F	Ctt/Ttt	-0,29	0	0	probably_damaging	1	neutral	0,71	neutral	4,6	neutral	-2,42	deleterious	-3,6	low_impact	1,45	damaging	0,56	damaging	0,06	deleterious	4,05	23,7	0,56	0,6	NA	NA	disease	0,79	disease	0,54	disease	0,61	2	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,87	low_impact	-3,6	medium_impact	0,45	medium_impact	0,12	0,51	0,8	23,05	7,06	N	0,15	N	0,99	polymorphism	1	0,06	rs28371809	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13385	13385	T	C	MI.21501	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1049	350	L	P	cTt/cCt	-0,06	0	0	probably_damaging	1	neutral	0,23	neutral	4,56	deleterious	-3,79	deleterious	-6,3	high_impact	4,2	damaging	0,54	damaging	0,03	deleterious	3,91	23,5	0,22	0,45	NA	NA	disease	0,89	disease	0,63	disease	0,72	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,93	low_impact	-3,6	medium_impact	-0,06	high_impact	2,63	0,52	0,8	23,05	7,06	N	0,31	N	0,99	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13385	13385	T	A	MI.21502	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1049	350	L	H	cTt/cAt	-0,06	0	0	probably_damaging	1	neutral	0,55	neutral	4,59	deleterious	-3,83	deleterious	-6,3	medium_impact	2,92	damaging	0,55	damaging	0,03	deleterious	4,15	23,8	0,39	0,5	NA	NA	disease	0,88	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,91	low_impact	-3,6	medium_impact	0,28	medium_impact	1,46	0,58	0,8	23,05	7,06	N	0,21	N	0,97	polymorphism	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13385	13385	T	G	MI.21503	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1049	350	L	R	cTt/cGt	-0,06	0	0	probably_damaging	1	neutral	0,4	neutral	4,58	neutral	-0,55	deleterious	-5,4	high_impact	3,5	damaging	0,58	damaging	0,03	deleterious	4,22	23,9	0,33	0,5	NA	NA	disease	0,92	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,94	low_impact	-3,6	medium_impact	0,14	medium_impact	1,99	0,75	0,85	23,05	7,06	N	0,24	N	1	polymorphism	0,98	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13387	13387	A	C	MI.21504	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1051	351	N	H	Aac/Cac	-5,1	0	0	probably_damaging	0,98	neutral	0,56	neutral	4,61	neutral	1,33	deleterious	-4,26	low_impact	1,16	neutral	0,69	neutral	0,49	deleterious	3,08	22,5	0,79	0,8	disease	0,56	disease	0,83	disease	0,59	disease	0,57	1	neutral	0,97	neutral	0,29	neutral	-2	deleterious	0,79	low_impact	-2,35	medium_impact	0,29	medium_impact	-0,14	0,46	0,8	4,15	9,29	N	0,23	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13387	13387	A	T	MI.21505	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1051	351	N	Y	Aac/Tac	-5,1	0	0	probably_damaging	0,98	neutral	1	neutral	4,54	neutral	-1,71	deleterious	-6,84	medium_impact	2,37	neutral	0,73	neutral	0,39	deleterious	3,73	23,3	0,62	0,65	disease	0,68	disease	0,92	disease	0,67	disease	0,75	5	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,84	low_impact	-2,35	high_impact	1,89	medium_impact	0,96	0,48	0,8	4,15	9,29	N	0,17	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13387	13387	A	G	MI.21506	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1051	351	N	D	Aac/Gac	-5,1	0	0	benign	0,12	neutral	0,3	neutral	4,57	neutral	-0,55	deleterious	-3,94	low_impact	1,82	neutral	0,77	neutral	0,74	deleterious	2,28	18,03	0,82	0,85	disease	0,63	disease	0,79	neutral	0,44	disease	0,54	1	neutral	0,65	deleterious	0,59	neutral	-6	deleterious	0,61	medium_impact	0,08	medium_impact	0,03	medium_impact	0,46	0,52	0,8	4,15	9,29	N	0,29	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13388	13388	A	T	MI.21507	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1052	351	N	I	aAc/aTc	2,69	0,12	0	probably_damaging	0,96	neutral	0,42	neutral	4,56	neutral	-2,39	deleterious	-7,7	medium_impact	2,82	neutral	0,7	neutral	0,52	deleterious	3,84	23,4	0,62	0,65	disease	0,65	disease	0,93	disease	0,62	disease	0,74	5	neutral	0,96	neutral	0,23	deleterious	1	deleterious	0,81	low_impact	-2,06	medium_impact	0,16	medium_impact	1,37	0,33	0,8	4,15	9,29	N	0,37	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13388	13388	A	G	MI.21508	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1052	351	N	S	aAc/aGc	2,69	0,12	0	benign	0,2	neutral	0,52	neutral	4,62	neutral	0,14	deleterious	-4,13	low_impact	0,94	neutral	0,76	neutral	0,78	neutral	1,24	11,93	0,84	0,85	neutral	0,46	disease	0,77	neutral	0,41	disease	0,52	0	neutral	0,38	deleterious	0,66	neutral	-6	neutral	0,29	medium_impact	-0,17	medium_impact	0,25	medium_impact	-0,34	0,22	0,8	4,15	9,29	N	0,3	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13388	13388	A	C	MI.21509	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1052	351	N	T	aAc/aCc	2,69	0,12	0	possibly_damaging	0,74	neutral	0,47	neutral	4,57	neutral	1,04	deleterious	-5,08	medium_impact	2,48	neutral	0,7	neutral	0,54	deleterious	1,88	15,46	0,73	0,75	neutral	0,34	disease	0,89	disease	0,54	disease	0,66	3	neutral	0,73	neutral	0,37	NA	0	deleterious	0,54	low_impact	-1,18	medium_impact	0,2	medium_impact	1,06	0,41	0,8	4,15	9,29	N	0,34	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6036	6036	G	C	MI.2151	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	133	45	G	R	Ggc/Cgc	-14,91	0	0	probably_damaging	1	deleterious	0	neutral	2,69	deleterious	-3,01	deleterious	-4,64	high_impact	4,62	damaging	0,46	damaging	0,02	deleterious	3,86	23,5	0,29	0,55	disease	0,77	disease	0,93	disease	0,72	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,17	0,78	0,9	3,9	6,63	N	0,46	N	0,95	polymorphism	0,83	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13389	13389	C	G	MI.21510	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1053	351	N	K	aaC/aaG	2	0,11	0	possibly_damaging	0,83	neutral	0,42	neutral	4,67	neutral	0,02	deleterious	-5,08	low_impact	1,36	neutral	0,73	neutral	0,55	deleterious	2,38	18,69	0,81	0,85	disease	0,61	disease	0,9	disease	0,58	disease	0,57	1	neutral	0,83	neutral	0,3	neutral	-3	deleterious	0,69	low_impact	-1,4	medium_impact	0,16	medium_impact	0,04	0,51	0,8	4,15	9,29	N	0,3	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13389	13389	C	A	MI.21511	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1053	351	N	K	aaC/aaA	2	0,11	0	possibly_damaging	0,83	neutral	0,42	neutral	4,67	neutral	0,02	deleterious	-5,08	low_impact	1,36	neutral	0,73	neutral	0,55	deleterious	2,86	21,7	0,81	0,85	disease	0,61	disease	0,9	disease	0,58	disease	0,57	1	neutral	0,83	neutral	0,3	neutral	-3	deleterious	0,69	low_impact	-1,4	medium_impact	0,16	medium_impact	0,04	0,51	0,8	4,15	9,29	N	0,3	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13390	13390	A	T	MI.21512	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1054	352	N	Y	Aat/Tat	-8,31	0	0	probably_damaging	1	neutral	1	neutral	3,7	deleterious	-3,09	deleterious	-5,32	high_impact	4,05	neutral	0,74	neutral	0,55	deleterious	3,58	23,2	0,41	0,5	disease	0,84	disease	0,85	disease	0,71	disease	0,8	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,86	low_impact	-3,6	high_impact	1,89	high_impact	2,5	0,47	0,8	10,45	13	N	0,27	N	0,9	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13390	13390	A	G	MI.21513	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1054	352	N	D	Aat/Gat	-8,31	0	0	probably_damaging	1	neutral	0,26	neutral	3,87	neutral	0,49	neutral	0,2	neutral_impact	0,18	neutral	0,77	neutral	0,98	neutral	0,99	10,63	0,83	0,85	neutral	0,32	neutral	0,14	neutral	0,35	neutral	0,22	6	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	-0,02	low_impact	-1,04	0,59	0,8	10,45	13	N	0,43	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13390	13390	A	C	MI.21514	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1054	352	N	H	Aat/Cat	-8,31	0	0	probably_damaging	1	neutral	0,55	neutral	3,85	neutral	1,33	deleterious	-3,09	low_impact	1,8	neutral	0,76	neutral	0,51	deleterious	3,01	22,3	0,79	0,8	neutral	0,34	disease	0,69	disease	0,71	disease	0,59	2	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,28	medium_impact	0,44	0,59	0,8	10,45	13	N	0,27	N	0,56	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13391	13391	A	G	MI.21515	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1055	352	N	S	aAt/aGt	0,4	0,2	0	probably_damaging	1	neutral	0,46	neutral	3,83	neutral	0,55	deleterious	-2,62	low_impact	1,93	neutral	0,74	neutral	0,6	deleterious	3,24	22,8	0,86	0,9	neutral	0,45	disease	0,72	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,19	medium_impact	0,56	0,31	0,8	10,45	13	N	0,26	N	0,39	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13391	13391	A	C	MI.21516	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1055	352	N	T	aAt/aCt	0,4	0,2	0	probably_damaging	1	neutral	0,43	neutral	3,82	neutral	0,45	deleterious	-3,52	medium_impact	2,54	neutral	0,7	neutral	0,58	deleterious	3,6	23,2	0,71	0,75	disease	0,57	disease	0,77	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,17	medium_impact	1,12	0,56	0,8	10,45	13	N	0,25	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13391	13391	A	T	MI.21517	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1055	352	N	I	aAt/aTt	0,4	0,2	0	probably_damaging	1	neutral	0,44	neutral	3,7	neutral	-2,2	deleterious	-5,75	medium_impact	2,9	neutral	0,72	neutral	0,51	deleterious	4,11	23,7	0,38	0,5	disease	0,71	disease	0,87	disease	0,69	disease	0,78	6	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,18	medium_impact	1,45	0,36	0,8	10,45	13	N	0,25	N	0,89	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13392	13392	T	A	MI.21518	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1056	352	N	K	aaT/aaA	5,67	0,72	0	probably_damaging	1	neutral	0,35	neutral	3,81	neutral	0,01	deleterious	-3,52	medium_impact	3,16	neutral	0,71	neutral	0,44	deleterious	4,36	24,1	0,78	0,8	neutral	0,35	disease	0,84	disease	0,69	disease	0,77	5	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,08	medium_impact	1,68	0,65	0,8	10,45	13	N	0,45	N	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13392	13392	T	G	MI.21519	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1056	352	N	K	aaT/aaG	5,67	0,72	0	probably_damaging	1	neutral	0,35	neutral	3,81	neutral	0,01	deleterious	-3,52	medium_impact	3,16	neutral	0,71	neutral	0,44	deleterious	4,05	23,7	0,78	0,8	neutral	0,35	disease	0,84	disease	0,69	disease	0,77	5	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,08	medium_impact	1,68	0,65	0,8	10,45	13	N	0,44	N	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6037	6037	G	C	MI.2152	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	134	45	G	A	gGc/gCc	4,29	1	0	probably_damaging	1	deleterious	0	neutral	2,73	neutral	-2,17	deleterious	-3,5	high_impact	3,82	damaging	0,58	damaging	0,05	deleterious	3,02	22,3	0,35	0,55	disease	0,68	disease	0,83	disease	0,63	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,43	0,6	0,9	3,9	6,63	N	0,41	N	0,64	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13393	13393	G	A	MI.21520	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1057	353	E	K	Gaa/Aaa	-4,19	0	0	probably_damaging	1	neutral	0,94	neutral	4,67	neutral	-1,5	deleterious	-3,6	medium_impact	3,23	damaging	0,41	damaging	0,13	deleterious	4,58	24,4	0,65	0,7	disease	0,54	disease	0,94	disease	0,78	disease	0,87	7	deleterious	1	deleterious	0,47	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,89	medium_impact	1,75	0,77	0,85	28,69	7,2	N	0,5	N	0,99	polymorphism	0,74	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13393	13393	G	C	MI.21521	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1057	353	E	Q	Gaa/Caa	-4,19	0	0	probably_damaging	1	neutral	0,69	neutral	4,58	neutral	-2,31	deleterious	-2,7	medium_impact	2,9	damaging	0,39	damaging	0,16	deleterious	3,42	23	0,76	0,8	disease	0,66	disease	0,85	disease	0,74	disease	0,77	5	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,42	medium_impact	1,45	0,75	0,85	28,69	7,2	N	0,44	N	0,89	polymorphism	0,93	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13394	13394	A	G	MI.21522	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1058	353	E	G	gAa/gGa	5,9	1	0	probably_damaging	1	neutral	0,59	neutral	4,54	neutral	-2,82	deleterious	-6,29	medium_impact	3,37	damaging	0,29	damaging	0,17	deleterious	4,38	24,1	0,67	0,7	disease	0,82	disease	0,83	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,32	medium_impact	1,88	0,51	0,8	28,69	7,2	P	0,88	P	0,51	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13394	13394	A	C	MI.21523	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1058	353	E	A	gAa/gCa	5,9	1	0	probably_damaging	1	neutral	1	neutral	4,6	neutral	-1,79	deleterious	-5,39	medium_impact	3,02	damaging	0,35	damaging	0,16	deleterious	3,8	23,4	0,67	0,7	disease	0,68	disease	0,85	disease	0,76	disease	0,78	6	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,84	low_impact	-3,6	high_impact	1,89	medium_impact	1,56	0,72	0,85	28,69	7,2	P	0,68	P	0,75	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13394	13394	A	T	MI.21524	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1058	353	E	V	gAa/gTa	5,9	1	0	probably_damaging	1	neutral	0,63	neutral	4,6	neutral	-2,98	deleterious	-6,29	medium_impact	2,94	damaging	0,33	damaging	0,14	deleterious	4,28	24	0,54	0,6	disease	0,66	disease	0,93	disease	0,77	disease	0,81	6	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	0,36	medium_impact	1,48	0,68	0,85	28,69	7,2	P	0,69	P	0,81	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13395	13395	A	T	MI.21525	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1059	353	E	D	gaA/gaT	8,42	1	0,01	probably_damaging	1	neutral	0,65	neutral	4,55	neutral	-2,2	deleterious	-2,7	medium_impact	2,77	damaging	0,47	damaging	0,14	deleterious	3,84	23,4	0,62	0,65	disease	0,72	disease	0,81	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,38	medium_impact	1,33	0,75	0,85	28,69	7,2	P	0,6	P	0,86	disease_causing	1	0,07	rs386829179	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13395	13395	A	C	MI.21526	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1059	353	E	D	gaA/gaC	8,42	1	0,01	probably_damaging	1	neutral	0,65	neutral	4,55	neutral	-2,2	deleterious	-2,7	medium_impact	2,77	damaging	0,47	damaging	0,14	deleterious	3,75	23,3	0,62	0,65	disease	0,72	disease	0,81	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,38	medium_impact	1,33	0,75	0,85	28,69	7,2	P	0,59	P	0,86	disease_causing	1	0,07	rs386829179	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13396	13396	C	G	MI.21527	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1060	354	Q	E	Caa/Gaa	-0,06	0,79	0	probably_damaging	1	neutral	1	neutral	4,51	neutral	-1,31	deleterious	-2,7	high_impact	4,36	damaging	0,43	damaging	0,05	deleterious	3,12	22,6	0,47	0,55	disease	0,66	disease	0,84	disease	0,68	disease	0,71	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,85	low_impact	-3,6	high_impact	1,89	high_impact	2,78	0,58	0,8	28,69	7,17	N	0,45	N	0,92	disease_causing	0,99	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13396	13396	C	A	MI.21528	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1060	354	Q	K	Caa/Aaa	-0,06	0,79	0	probably_damaging	1	neutral	0,94	neutral	4,52	neutral	-1,49	deleterious	-3,6	high_impact	3,67	damaging	0,43	damaging	0,03	deleterious	4,12	23,8	0,55	0,6	disease	0,63	disease	0,91	disease	0,72	disease	0,77	5	deleterious	1	deleterious	0,47	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,89	high_impact	2,15	0,38	0,8	28,69	7,17	N	0,44	N	0,96	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13397	13397	A	G	MI.21529	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1061	354	Q	R	cAa/cGa	5,44	1	0	probably_damaging	1	neutral	0,62	neutral	4,63	neutral	0,56	deleterious	-3,6	medium_impact	2,61	damaging	0,5	damaging	0,03	deleterious	3,38	23	0,58	0,65	neutral	0,46	disease	0,89	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,35	medium_impact	1,18	0,45	0,8	28,69	7,17	N	0,44	N	0,85	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6037	6037	G	A	MI.2153	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	134	45	G	D	gGc/gAc	4,29	1	0	probably_damaging	1	deleterious	0,01	neutral	2,81	neutral	-1,19	deleterious	-4,03	high_impact	3,77	damaging	0,38	damaging	0,02	deleterious	3,74	23,3	0,28	0,55	neutral	0,42	disease	0,92	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,58	medium_impact	-0,92	high_impact	2,38	0,44	0,9	3,9	6,63	P	0,63	P	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13397	13397	A	C	MI.21530	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1061	354	Q	P	cAa/cCa	5,44	1	0	probably_damaging	1	neutral	0,34	neutral	4,42	deleterious	-4,22	deleterious	-5,4	high_impact	5,05	damaging	0,41	damaging	0,05	deleterious	3,22	22,7	0,27	0,45	disease	0,85	disease	0,91	disease	0,83	disease	0,83	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,07	high_impact	3,41	0,44	0,8	28,69	7,17	P	0,75	P	0,95	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13397	13397	A	T	MI.21531	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1061	354	Q	L	cAa/cTa	5,44	1	0	probably_damaging	1	neutral	0,59	neutral	4,44	neutral	-2,65	deleterious	-6,29	high_impact	3,9	damaging	0,43	damaging	0,03	deleterious	3,65	23,2	0,37	0,5	disease	0,81	disease	0,91	disease	0,7	disease	0,77	5	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,32	high_impact	2,36	0,33	0,8	28,69	7,17	P	0,61	P	0,96	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13398	13398	A	C	MI.21532	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1062	354	Q	H	caA/caC	8,42	1	0	probably_damaging	1	neutral	0,38	neutral	4,43	deleterious	-3,01	deleterious	-4,5	high_impact	3,96	damaging	0,44	damaging	0,03	deleterious	3,5	23,1	0,58	0,65	disease	0,77	disease	0,85	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,12	high_impact	2,41	0,54	0,8	28,69	7,17	P	0,65	P	0,94	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13398	13398	A	T	MI.21533	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1062	354	Q	H	caA/caT	8,42	1	0	probably_damaging	1	neutral	0,38	neutral	4,43	deleterious	-3,01	deleterious	-4,5	high_impact	3,96	damaging	0,44	damaging	0,03	deleterious	3,67	23,3	0,58	0,65	disease	0,77	disease	0,85	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,12	high_impact	2,41	0,54	0,8	28,69	7,17	P	0,68	P	0,94	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13399	13399	G	A	MI.21534	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1063	355	D	N	Gat/Aat	1,08	1	0	probably_damaging	1	neutral	0,56	neutral	4,6	neutral	-1,98	deleterious	-4,43	medium_impact	3,13	damaging	0,16	neutral	0,41	deleterious	4,35	24,1	0,79	0,8	disease	0,5	disease	0,9	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,29	medium_impact	1,66	0,78	0,85	27,53	7,14	P	0,95	P	0,98	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13399	13399	G	C	MI.21535	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1063	355	D	H	Gat/Cat	1,08	1	0	probably_damaging	1	neutral	0,3	neutral	4,49	deleterious	-3,92	deleterious	-6,16	high_impact	4,59	damaging	0,33	neutral	0,3	deleterious	3,71	23,3	0,48	0,55	disease	0,79	disease	0,92	disease	0,76	disease	0,82	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,03	high_impact	2,99	0,59	0,8	27,53	7,14	P	0,69	P	0,99	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13399	13399	G	T	MI.21536	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1063	355	D	Y	Gat/Tat	1,08	1	0	probably_damaging	1	neutral	0,4	neutral	4,52	deleterious	-3,95	deleterious	-7,95	high_impact	4,25	damaging	0,37	neutral	0,31	deleterious	3,97	23,6	0,29	0,45	disease	0,78	disease	0,96	disease	0,76	disease	0,86	7	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	0,14	high_impact	2,68	0,53	0,8	27,53	7,14	P	0,67	P	0,99	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13400	13400	A	G	MI.21537	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1064	355	D	G	gAt/gGt	9,11	1	0	probably_damaging	1	neutral	0,48	neutral	4,49	deleterious	-4,33	deleterious	-6,23	high_impact	4,59	damaging	0,27	neutral	0,39	deleterious	3,96	23,6	0,48	0,55	disease	0,87	disease	0,91	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,21	high_impact	2,99	0,42	0,8	27,53	7,14	P	0,93	P	0,98	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13400	13400	A	T	MI.21538	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1064	355	D	V	gAt/gTt	9,11	1	0	probably_damaging	1	neutral	0,43	neutral	4,49	deleterious	-4,52	deleterious	-8,01	high_impact	4,8	damaging	0,23	neutral	0,31	deleterious	3,66	23,2	0,25	0,45	disease	0,88	disease	0,95	disease	0,72	disease	0,83	7	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,17	high_impact	3,18	0,49	0,8	27,53	7,14	P	0,9	P	0,99	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13400	13400	A	C	MI.21539	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1064	355	D	A	gAt/gCt	9,11	1	0	probably_damaging	1	neutral	0,85	neutral	4,53	deleterious	-3,24	deleterious	-7,12	high_impact	4,17	damaging	0,35	neutral	0,41	deleterious	3,56	23,1	0,37	0,5	disease	0,76	disease	0,91	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,43	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,65	high_impact	2,61	0,52	0,8	27,53	7,14	P	0,73	P	0,94	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6037	6037	G	T	MI.2154	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	134	45	G	V	gGc/gTc	4,29	1	0	probably_damaging	1	deleterious	0	neutral	2,68	deleterious	-3,32	deleterious	-5,31	high_impact	4,62	damaging	0,49	damaging	0,03	deleterious	3,66	23,2	0,27	0,55	disease	0,85	disease	0,92	disease	0,65	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,17	0,5	0,9	3,9	6,63	P	0,5	N	0,93	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13401	13401	T	A	MI.21540	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1065	355	D	E	gaT/gaA	6,59	1	0	probably_damaging	1	neutral	1	neutral	4,57	neutral	-1,76	deleterious	-3,55	high_impact	3,62	damaging	0,32	neutral	0,32	deleterious	4,14	23,8	0,59	0,65	disease	0,62	disease	0,91	disease	0,6	disease	0,69	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,88	low_impact	-3,6	high_impact	1,89	high_impact	2,1	0,61	0,8	27,53	7,14	P	0,78	P	0,91	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13401	13401	T	G	MI.21541	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1065	355	D	E	gaT/gaG	6,59	1	0	probably_damaging	1	neutral	1	neutral	4,57	neutral	-1,76	deleterious	-3,55	high_impact	3,62	damaging	0,32	neutral	0,32	deleterious	4,04	23,7	0,59	0,65	disease	0,62	disease	0,91	disease	0,6	disease	0,69	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,88	low_impact	-3,6	high_impact	1,89	high_impact	2,1	0,61	0,8	27,53	7,14	P	0,78	P	0,91	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13402	13402	A	G	MI.21542	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1066	356	I	V	Att/Gtt	-1,44	0	0	benign	0,08	neutral	0,62	neutral	4,43	neutral	-2,18	neutral	-0,89	low_impact	1,89	neutral	0,8	neutral	0,65	neutral	1,01	10,73	0,67	0,7	disease	0,57	disease	0,6	disease	0,54	disease	0,51	0	neutral	0,29	deleterious	0,77	neutral	-6	neutral	0,23	medium_impact	0,26	medium_impact	0,35	medium_impact	0,52	0,64	0,8	21,72	6,99	N	0,23	N	0,74	disease_causing	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13402	13402	A	C	MI.21543	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1066	356	I	L	Att/Ctt	-1,44	0	0	possibly_damaging	0,52	neutral	0,86	neutral	4,68	neutral	-0,84	neutral	-1,8	low_impact	1,22	neutral	0,68	neutral	0,62	deleterious	1,84	15,25	0,43	0,55	neutral	0,47	disease	0,73	neutral	0,46	disease	0,52	0	neutral	0,43	deleterious	0,67	neutral	-3	neutral	0,31	medium_impact	-0,78	medium_impact	0,67	medium_impact	-0,09	0,81	0,85	21,72	6,99	N	0,24	N	0,86	disease_causing	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13402	13402	A	T	MI.21544	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1066	356	I	F	Att/Ttt	-1,44	0	0	probably_damaging	0,96	neutral	0,75	neutral	4,35	deleterious	-3,47	deleterious	-3,6	medium_impact	3,25	neutral	0,67	neutral	0,34	deleterious	3,48	23,1	0,31	0,45	disease	0,7	disease	0,86	disease	0,67	disease	0,72	4	neutral	0,95	neutral	0,4	deleterious	1	deleterious	0,78	low_impact	-2,06	medium_impact	0,5	medium_impact	1,77	0,82	0,85	21,72	6,99	N	0,23	N	0,96	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13403	13403	T	G	MI.21545	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1067	356	I	S	aTt/aGt	6,81	1	0	probably_damaging	0,94	neutral	0,74	neutral	4,35	deleterious	-4,63	deleterious	-5,39	medium_impact	3,38	neutral	0,7	neutral	0,4	deleterious	4,09	23,7	0,23	0,45	disease	0,85	disease	0,92	disease	0,68	disease	0,79	6	neutral	0,93	neutral	0,4	deleterious	1	deleterious	0,8	low_impact	-1,88	medium_impact	0,48	medium_impact	1,88	0,7	0,85	21,72	6,99	N	0,46	N	0,96	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13403	13403	T	A	MI.21546	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1067	356	I	N	aTt/aAt	6,81	1	0	probably_damaging	0,98	neutral	0,55	neutral	4,32	deleterious	-6,02	deleterious	-6,29	high_impact	3,87	neutral	0,66	neutral	0,36	deleterious	4,38	24,1	0,2	0,45	disease	0,87	disease	0,92	disease	0,67	disease	0,8	6	neutral	0,98	neutral	0,29	deleterious	2	deleterious	0,87	low_impact	-2,35	medium_impact	0,28	high_impact	2,33	0,67	0,85	21,72	6,99	P	0,5	N	0,99	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13403	13403	T	C	MI.21547	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1067	356	I	T	aTt/aCt	6,81	1	0	possibly_damaging	0,83	neutral	0,65	neutral	4,41	deleterious	-4	deleterious	-4,49	medium_impact	3,23	neutral	0,68	neutral	0,38	deleterious	3	22,2	0,4	0,5	disease	0,82	disease	0,89	disease	0,66	disease	0,75	5	neutral	0,8	neutral	0,41	NA	0	deleterious	0,7	low_impact	-1,4	medium_impact	0,38	medium_impact	1,75	0,71	0,85	21,72	6,99	N	0,49	N	0,96	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13404	13404	T	G	MI.21548	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1068	356	I	M	atT/atG	7,27	1	0	probably_damaging	0,96	neutral	0,3	neutral	4,44	neutral	-1,32	deleterious	-2,69	low_impact	1,73	neutral	0,7	neutral	0,66	deleterious	3,44	23	0,46	0,55	disease	0,53	disease	0,67	disease	0,64	disease	0,51	0	neutral	0,96	neutral	0,17	neutral	-2	deleterious	0,72	low_impact	-2,06	medium_impact	0,03	medium_impact	0,38	0,9	0,95	21,72	6,99	P	0,48	N	0,76	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13404	13404	T	A	MI.21549	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1068	356	I	M	atT/atA	7,27	1	0	probably_damaging	0,96	neutral	0,3	neutral	4,44	neutral	-1,32	deleterious	-2,69	low_impact	1,73	neutral	0,7	neutral	0,66	deleterious	3,66	23,2	0,46	0,55	disease	0,53	disease	0,67	disease	0,64	disease	0,51	0	neutral	0,96	neutral	0,17	neutral	-2	deleterious	0,72	low_impact	-2,06	medium_impact	0,03	medium_impact	0,38	0,9	0,95	21,72	6,99	P	0,49	N	0,76	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6039	6039	A	T	MI.2155	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	136	46	N	Y	Aac/Tac	-15,6	0	0	benign	0,3	neutral	0,11	neutral	2,73	deleterious	-3,16	neutral	-1,24	neutral_impact	0,56	neutral	0,74	neutral	0,73	deleterious	3,48	23,1	0,37	0,55	disease	0,56	disease	0,51	disease	0,51	disease	0,56	1	neutral	0,87	neutral	0,41	neutral	-6	neutral	0,42	medium_impact	-0,41	medium_impact	-0,31	medium_impact	-0,58	0,33	0,9	15,79	51,88	N	0,41	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13405	13405	C	G	MI.21550	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1069	357	R	G	Cga/Gga	-2,58	0	0	probably_damaging	1	neutral	0,44	neutral	4,5	neutral	-2,78	deleterious	-6,27	high_impact	3,87	damaging	0,31	damaging	0,09	deleterious	4,26	23,9	0,39	0,5	disease	0,82	disease	0,81	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,18	high_impact	2,33	0,43	0,8	26,53	7,28	P	0,53	P	0,97	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13405	13405	C	T	MI.21551	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1069	357	R	W	Cga/Tga	-2,58	0	0	probably_damaging	1	neutral	0,19	neutral	4,46	deleterious	-5,1	deleterious	-7,15	high_impact	3,87	damaging	0,35	damaging	0,06	deleterious	5,18	25,5	0,44	0,55	disease	0,97	disease	0,9	disease	0,61	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,12	high_impact	2,33	0,77	0,85	26,53	7,28	N	0,43	N	1	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13406	13406	G	C	MI.21552	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1070	357	R	P	cGa/cCa	5,44	1	0	probably_damaging	1	neutral	0,28	neutral	4,47	deleterious	-3,74	deleterious	-6,27	high_impact	4,17	damaging	0,35	damaging	0,07	deleterious	4,24	23,9	0,31	0,45	disease	0,8	disease	0,91	disease	0,8	disease	0,82	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,01	high_impact	2,61	0,32	0,8	26,53	7,28	P	0,71	P	0,99	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13406	13406	G	T	MI.21553	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1070	357	R	L	cGa/cTa	5,44	1	0	probably_damaging	1	neutral	0,73	neutral	4,57	deleterious	-3,49	deleterious	-6,23	high_impact	4,03	damaging	0,29	damaging	0,07	deleterious	4,36	24,1	0,41	0,5	disease	0,73	disease	0,92	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,47	high_impact	2,48	0,35	0,8	26,53	7,28	P	0,74	P	1	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13406	13406	G	A	MI.21554	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1070	357	R	Q	cGa/cAa	5,44	1	0	probably_damaging	1	neutral	0,46	neutral	4,55	neutral	-2,76	deleterious	-3,58	high_impact	3,75	damaging	0,37	damaging	0,06	deleterious	4,57	24,4	0,66	0,7	disease	0,75	disease	0,9	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,19	high_impact	2,22	0,9	0,95	26,53	7,28	P	0,7	P	0,99	disease_causing	1	0,24	.	.	.	.	.	.	COSM1155537	.	.	.	.	.	.	.	.
chrM	13408	13408	A	G	MI.21555	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1072	358	K	E	Aaa/Gaa	-0,06	0,91	0	probably_damaging	1	neutral	1	neutral	4,62	neutral	-0,82	deleterious	-3,57	medium_impact	2,63	damaging	0,59	damaging	0,13	deleterious	4,09	23,7	0,64	0,7	neutral	0,48	disease	0,87	disease	0,66	disease	0,72	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,83	low_impact	-3,6	high_impact	1,89	medium_impact	1,2	0,8	0,85	27,36	7,29	N	0,21	N	0,84	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13408	13408	A	C	MI.21556	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1072	358	K	Q	Aaa/Caa	-0,06	0,91	0	probably_damaging	1	neutral	0,6	neutral	4,58	neutral	-1,68	deleterious	-3,56	medium_impact	2,81	damaging	0,54	damaging	0,15	deleterious	3,55	23,1	0,66	0,7	disease	0,63	disease	0,83	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,33	medium_impact	1,36	0,78	0,85	27,36	7,29	N	0,26	N	0,82	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13409	13409	A	T	MI.21557	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1073	358	K	M	aAa/aTa	8,42	1	0	probably_damaging	1	neutral	0,14	neutral	4,56	deleterious	-4,41	deleterious	-5,37	medium_impact	2,51	damaging	0,54	damaging	0,27	deleterious	3,75	23,3	0,28	0,45	disease	0,87	disease	0,82	disease	0,56	disease	0,67	3	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	-0,2	medium_impact	1,09	0,55	0,8	27,36	7,29	N	0,47	N	0,4	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13409	13409	A	C	MI.21558	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1073	358	K	T	aAa/aCa	8,42	1	0	probably_damaging	1	neutral	0,6	neutral	4,58	neutral	-2,64	deleterious	-5,37	medium_impact	2,95	damaging	0,58	damaging	0,11	deleterious	3,46	23	0,4	0,5	disease	0,77	disease	0,86	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,33	medium_impact	1,49	0,65	0,8	27,36	7,29	N	0,42	N	0,75	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13410	13410	A	C	MI.21559	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1074	358	K	N	aaA/aaC	6,59	1	0	probably_damaging	1	neutral	0,51	neutral	4,67	neutral	-1,6	deleterious	-4,48	medium_impact	2,36	damaging	0,51	damaging	0,11	deleterious	3,84	23,4	0,67	0,7	disease	0,69	disease	0,8	disease	0,65	disease	0,54	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,24	medium_impact	0,95	0,71	0,85	27,36	7,29	N	0,49	N	0,63	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6039	6039	A	G	MI.2156	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	136	46	N	D	Aac/Gac	-15,6	0	0	benign	0,06	deleterious	0,03	neutral	2,92	neutral	-1,36	neutral	-0,51	neutral_impact	0,74	neutral	0,67	neutral	0,54	deleterious	1,92	15,69	0,66	0,7	neutral	0,28	neutral	0,35	neutral	0,38	neutral	0,45	1	neutral	0,97	deleterious	0,49	neutral	-2	neutral	0,17	medium_impact	0,37	medium_impact	-0,65	medium_impact	-0,42	0,34	0,9	15,79	51,88	N	0,48	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13410	13410	A	T	MI.21560	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1074	358	K	N	aaA/aaT	6,59	1	0	probably_damaging	1	neutral	0,51	neutral	4,67	neutral	-1,6	deleterious	-4,48	medium_impact	2,36	damaging	0,51	damaging	0,11	deleterious	3,9	23,5	0,67	0,7	disease	0,69	disease	0,8	disease	0,65	disease	0,54	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,24	medium_impact	0,95	0,71	0,85	27,36	7,29	N	0,5	N	0,63	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13411	13411	A	T	MI.21561	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1075	359	M	L	Ata/Tta	0,17	0,97	0	probably_damaging	0,98	neutral	0,77	neutral	4,81	neutral	-0,06	deleterious	-2,7	low_impact	1,82	damaging	0,54	damaging	0,08	deleterious	3,26	22,8	0,49	0,55	neutral	0,43	disease	0,79	disease	0,65	disease	0,69	4	deleterious	0,98	neutral	0,4	neutral	-2	deleterious	0,69	low_impact	-2,35	medium_impact	0,52	medium_impact	0,46	0,64	0,8	27,69	7,21	N	0,27	N	0,98	disease_causing	0,64	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13411	13411	A	C	MI.21562	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1075	359	M	L	Ata/Cta	0,17	0,97	0	probably_damaging	0,98	neutral	0,77	neutral	4,81	neutral	-0,06	deleterious	-2,7	low_impact	1,82	damaging	0,54	damaging	0,08	deleterious	3,18	22,7	0,49	0,55	neutral	0,43	disease	0,79	disease	0,65	disease	0,69	4	deleterious	0,98	neutral	0,4	neutral	-2	deleterious	0,69	low_impact	-2,35	medium_impact	0,52	medium_impact	0,46	0,64	0,8	27,69	7,21	N	0,27	N	0,98	disease_causing	0,64	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13411	13411	A	G	MI.21563	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1075	359	M	V	Ata/Gta	0,17	0,97	0	probably_damaging	0,99	neutral	0,63	neutral	4,63	neutral	-2,35	deleterious	-3,59	high_impact	3,52	damaging	0,53	damaging	0,08	deleterious	2,69	20,8	0,46	0,55	disease	0,65	disease	0,82	disease	0,73	disease	0,75	5	deleterious	0,99	neutral	0,32	deleterious	2	deleterious	0,77	low_impact	-2,64	medium_impact	0,36	high_impact	2,01	0,58	0,8	27,69	7,21	N	0,33	N	0,95	disease_causing	0,69	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13412	13412	T	C	MI.21564	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1076	359	M	T	aTa/aCa	5,21	1	0	probably_damaging	1	neutral	0,76	neutral	4,59	deleterious	-3,72	deleterious	-5,39	medium_impact	3,11	damaging	0,55	damaging	0,13	deleterious	3,1	22,5	0,37	0,5	disease	0,82	disease	0,88	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,88	low_impact	-3,6	medium_impact	0,51	medium_impact	1,64	0,37	0,8	27,69	7,21	N	0,37	N	0,99	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13412	13412	T	A	MI.21565	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1076	359	M	K	aTa/aAa	5,21	1	0	probably_damaging	1	neutral	0,96	neutral	4,53	deleterious	-4,91	deleterious	-5,39	high_impact	3,83	neutral	0,61	damaging	0,09	deleterious	4,36	24,1	0,17	0,45	disease	0,91	disease	0,92	disease	0,79	disease	0,85	7	deleterious	1	deleterious	0,48	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	1	high_impact	2,3	0,36	0,8	27,69	7,21	N	0,51	P	1	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13413	13413	A	C	MI.21566	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1077	359	M	I	atA/atC	5,67	1	0	probably_damaging	0,99	neutral	0,47	neutral	4,58	neutral	-2,29	deleterious	-3,59	medium_impact	2,35	damaging	0,6	damaging	0,12	deleterious	3,48	23,1	0,46	0,55	disease	0,73	disease	0,81	disease	0,73	disease	0,75	5	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,82	low_impact	-2,64	medium_impact	0,2	medium_impact	0,94	0,7	0,85	27,69	7,21	N	0,48	N	0,94	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13413	13413	A	T	MI.21567	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1077	359	M	I	atA/atT	5,67	1	0	probably_damaging	0,99	neutral	0,47	neutral	4,58	neutral	-2,29	deleterious	-3,59	medium_impact	2,35	damaging	0,6	damaging	0,12	deleterious	3,66	23,2	0,46	0,55	disease	0,73	disease	0,81	disease	0,73	disease	0,75	5	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,82	low_impact	-2,64	medium_impact	0,2	medium_impact	0,94	0,7	0,85	27,69	7,21	N	0,49	N	0,94	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13414	13414	G	C	MI.21568	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1078	360	G	R	Gga/Cga	0,4	0,98	0	probably_damaging	1	neutral	0,46	neutral	4,55	neutral	-2,92	deleterious	-7,19	medium_impact	3,5	damaging	0,56	damaging	0,02	deleterious	3,97	23,6	0,31	0,45	disease	0,72	disease	0,91	disease	0,81	disease	0,83	7	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,9	low_impact	-3,6	medium_impact	0,19	medium_impact	1,99	0,91	0,95	28,19	7,23	N	0,41	N	1	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13414	13414	G	T	MI.21569	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1078	360	G	W	Gga/Tga	0,4	0,98	0	probably_damaging	1	neutral	0,18	neutral	4,4	deleterious	-8,33	deleterious	-7,19	high_impact	4,45	damaging	0,56	damaging	0,02	deleterious	4,45	24,2	0,19	0,45	disease	0,98	disease	0,91	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,13	high_impact	2,86	0,53	0,8	28,19	7,23	N	0,48	N	1	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6039	6039	A	C	MI.2157	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	136	46	N	H	Aac/Cac	-15,6	0	0	possibly_damaging	0,49	neutral	0,07	neutral	2,79	neutral	-2,75	neutral	-0,91	low_impact	1,84	neutral	0,75	neutral	0,63	deleterious	2,87	21,7	0,59	0,65	neutral	0,47	neutral	0,35	disease	0,51	neutral	0,47	1	neutral	0,92	neutral	0,29	neutral	-3	neutral	0,38	medium_impact	-0,74	medium_impact	-0,43	medium_impact	0,6	0,39	0,9	15,79	51,88	N	0,46	N	0,27	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13415	13415	G	A	MI.21570	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1079	360	G	E	gGa/gAa	7,27	1	0	probably_damaging	1	neutral	0,49	neutral	4,55	deleterious	-3,88	deleterious	-7,19	high_impact	4,66	damaging	0,54	damaging	0,02	deleterious	3,96	23,6	0,28	0,45	disease	0,75	disease	0,9	disease	0,8	disease	0,82	6	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,22	high_impact	3,05	0,73	0,85	28,19	7,23	P	0,65	P	1	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13415	13415	G	C	MI.21571	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1079	360	G	A	gGa/gCa	7,27	1	0	probably_damaging	1	neutral	0,68	neutral	4,51	neutral	-2,94	deleterious	-5,39	high_impact	3,58	damaging	0,55	damaging	0,03	deleterious	3,2	22,7	0,4	0,5	disease	0,68	disease	0,78	disease	0,59	disease	0,67	3	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,41	high_impact	2,07	0,78	0,85	28,19	7,23	N	0,39	N	0,79	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13415	13415	G	T	MI.21572	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1079	360	G	V	gGa/gTa	7,27	1	0	probably_damaging	1	neutral	0,56	neutral	4,43	deleterious	-5,45	deleterious	-8,09	high_impact	4,66	damaging	0,54	damaging	0,02	deleterious	3,84	23,4	0,23	0,45	disease	0,89	disease	0,9	disease	0,71	disease	0,81	6	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,29	high_impact	3,05	0,54	0,8	28,19	7,23	P	0,56	P	0,98	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13417	13417	G	T	MI.21573	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1081	361	G	W	Gga/Tga	-9,46	0	0	probably_damaging	1	neutral	0,18	neutral	4,3	deleterious	-8,94	deleterious	-7,17	high_impact	4,73	neutral	0,68	damaging	0,06	deleterious	4,57	24,4	0,24	0,45	disease	1	disease	0,89	disease	0,75	disease	0,88	8	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,13	high_impact	3,12	0,38	0,8	8,13	12,67	N	0,5	N	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13417	13417	G	C	MI.21574	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1081	361	G	R	Gga/Cga	-9,46	0	0	probably_damaging	1	neutral	0,36	neutral	4,39	deleterious	-5,61	deleterious	-7,15	high_impact	3,58	neutral	0,65	damaging	0,05	deleterious	4,06	23,7	0,3	0,45	disease	0,97	disease	0,89	disease	0,81	disease	0,85	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	0,1	high_impact	2,07	0,82	0,85	8,13	12,67	N	0,32	N	0,97	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13418	13418	G	A	MI.21575	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1082	361	G	E	gGa/gAa	1,54	0,97	0	probably_damaging	0,99	neutral	0,29	neutral	4,39	deleterious	-5,18	deleterious	-7,15	high_impact	4,38	neutral	0,67	damaging	0,06	deleterious	3,98	23,6	0,32	0,5	disease	0,96	disease	0,88	disease	0,81	disease	0,86	7	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,91	low_impact	-2,64	medium_impact	0,02	high_impact	2,8	0,57	0,8	8,13	12,67	N	0,5	N	0,95	polymorphism	1	0,35	.	.	.	.	.	.	COSM1155540	.	.	.	.	.	.	.	.
chrM	13418	13418	G	T	MI.21576	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1082	361	G	V	gGa/gTa	1,54	0,97	0	probably_damaging	0,99	neutral	0,51	neutral	4,33	deleterious	-6,4	deleterious	-8,05	high_impact	3,92	neutral	0,63	damaging	0,05	deleterious	3,84	23,4	0,27	0,45	disease	0,96	disease	0,88	disease	0,69	disease	0,83	7	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,91	low_impact	-2,64	medium_impact	0,24	high_impact	2,38	0,38	0,8	8,13	12,67	N	0,4	N	0,96	polymorphism	0,99	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13418	13418	G	C	MI.21577	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1082	361	G	A	gGa/gCa	1,54	0,97	0	probably_damaging	0,95	neutral	0,52	neutral	4,39	deleterious	-4,96	deleterious	-5,36	medium_impact	2,34	neutral	0,63	neutral	0,28	deleterious	3,14	22,6	0,29	0,45	disease	0,81	disease	0,69	disease	0,53	disease	0,57	1	neutral	0,94	neutral	0,29	deleterious	1	deleterious	0,86	low_impact	-1,96	medium_impact	0,25	medium_impact	0,94	0,74	0,85	8,13	12,67	N	0,35	N	0,78	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13420	13420	C	G	MI.21578	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1084	362	L	V	Cta/Gta	-14,73	0	0	probably_damaging	1	neutral	0,57	neutral	4,25	deleterious	-3,67	deleterious	-2,7	medium_impact	2,62	neutral	0,69	damaging	0,14	deleterious	3,48	23,1	0,46	0,55	disease	0,7	disease	0,56	neutral	0,27	neutral	0,5	0	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,3	medium_impact	1,19	0,66	0,8	9,62	12,09	N	0,21	N	0,49	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13420	13420	C	A	MI.21579	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1084	362	L	M	Cta/Ata	-14,73	0	0	probably_damaging	1	neutral	0,3	neutral	4,21	deleterious	-4,78	neutral	-1,8	medium_impact	1,96	neutral	0,76	neutral	0,44	deleterious	2,56	19,86	0,39	0,5	disease	0,75	neutral	0,19	neutral	0,19	neutral	0,48	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,03	medium_impact	0,59	0,78	0,85	9,62	12,09	N	0,42	N	0,16	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6040	6040	A	C	MI.2158	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	137	46	N	T	aAc/aCc	-1,03	0	0,02	benign	0	neutral	0,42	neutral	2,81	neutral	2,02	neutral	0,47	neutral_impact	-0,78	neutral	0,78	neutral	0,98	deleterious	0,43	6,85	0,54	0,6	neutral	0,21	neutral	0,26	neutral	0,22	neutral	0,43	1	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,12	low_impact	-1,82	0,39	0,9	15,79	51,88	N	0,39	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13421	13421	T	G	MI.21580	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1085	362	L	R	cTa/cGa	-1,44	0	0	probably_damaging	1	neutral	0,48	neutral	4,14	deleterious	-6,8	deleterious	-5,39	high_impact	4,27	neutral	0,61	damaging	0,08	deleterious	4,24	23,9	0,3	0,45	disease	0,94	disease	0,88	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	0,21	high_impact	2,7	0,54	0,8	9,62	12,09	N	0,35	N	0,98	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13421	13421	T	C	MI.21581	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1085	362	L	P	cTa/cCa	-1,44	0	0	probably_damaging	1	neutral	0,27	neutral	4,13	deleterious	-7,58	deleterious	-6,29	high_impact	4,82	damaging	0,55	damaging	0,08	deleterious	4	23,6	0,31	0,45	disease	0,95	disease	0,85	disease	0,73	disease	0,83	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,93	low_impact	-3,6	medium_impact	-0,01	high_impact	3,2	0,57	0,8	9,62	12,09	P	0,55	P	0,88	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13421	13421	T	A	MI.21582	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1085	362	L	Q	cTa/cAa	-1,44	0	0	probably_damaging	1	neutral	0,42	neutral	4,13	deleterious	-7,1	deleterious	-5,39	high_impact	4,47	neutral	0,68	damaging	0,09	deleterious	4,3	24	0,27	0,45	disease	0,94	disease	0,8	disease	0,61	disease	0,81	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,16	high_impact	2,88	0,65	0,8	9,62	12,09	N	0,35	N	0,93	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13423	13423	C	G	MI.21583	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1087	363	L	V	Ctc/Gtc	-5,33	0	0	benign	0,36	neutral	0,67	neutral	4,62	neutral	-0,18	neutral	-0,63	neutral_impact	0,75	neutral	0,81	neutral	0,71	neutral	1,63	14,03	0,62	0,65	neutral	0,44	neutral	0,29	neutral	0,23	neutral	0,46	1	neutral	0,29	deleterious	0,66	neutral	-6	deleterious	0,5	medium_impact	-0,51	medium_impact	0,4	medium_impact	-0,52	0,41	0,8	25,37	15,03	N	0,27	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13423	13423	C	A	MI.21584	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1087	363	L	I	Ctc/Atc	-5,33	0	0	benign	0,36	neutral	0,51	neutral	4,61	neutral	-0,17	neutral	-0,22	neutral_impact	-0,16	neutral	0,84	neutral	0,77	deleterious	2,41	18,89	0,47	0,55	neutral	0,44	neutral	0,23	neutral	0,22	neutral	0,46	1	neutral	0,41	deleterious	0,58	neutral	-6	deleterious	0,46	medium_impact	-0,51	medium_impact	0,24	low_impact	-1,35	0,5	0,8	25,37	15,03	N	0,34	N	0,28	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13423	13423	C	T	MI.21585	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1087	363	L	F	Ctc/Ttc	-5,33	0	0	benign	0,01	neutral	0,73	neutral	4,6	neutral	-0,64	neutral	2,97	neutral_impact	-0,2	neutral	0,92	neutral	0,97	neutral	-0,58	0,14	0,53	0,6	neutral	0,47	neutral	0,21	neutral	0,11	neutral	0,37	3	neutral	0,24	deleterious	0,86	neutral	-6	neutral	0,16	medium_impact	1,15	medium_impact	0,47	low_impact	-1,39	0,52	0,8	25,37	15,03	N	0,32	N	0,19	polymorphism	1	0	rs879030221	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13424	13424	T	C	MI.21586	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1088	363	L	P	cTc/cCc	-0,06	0	0	possibly_damaging	0,9	neutral	0,38	neutral	4,47	deleterious	-3,11	deleterious	-2,84	low_impact	1,86	damaging	0,57	neutral	0,45	deleterious	2,82	21,5	0,3	0,45	disease	0,85	disease	0,76	disease	0,55	disease	0,8	6	neutral	0,91	neutral	0,24	neutral	-3	deleterious	0,86	low_impact	-1,65	medium_impact	0,12	medium_impact	0,5	0,38	0,8	25,37	15,03	N	0,25	N	0,9	polymorphism	1	0,06	.	.	.	.	.	.	COSM1155541	.	.	.	.	.	.	.	.
chrM	13424	13424	T	A	MI.21587	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1088	363	L	H	cTc/cAc	-0,06	0	0	probably_damaging	0,95	neutral	0,6	neutral	4,47	neutral	-1,98	neutral	-0,07	neutral_impact	-0,24	neutral	0,8	neutral	0,84	neutral	1,6	13,87	0,34	0,5	disease	0,69	neutral	0,15	neutral	0,12	neutral	0,38	3	neutral	0,95	neutral	0,33	neutral	-2	deleterious	0,7	low_impact	-1,96	medium_impact	0,33	low_impact	-1,42	0,59	0,8	25,37	15,03	N	0,33	N	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13424	13424	T	G	MI.21588	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1088	363	L	R	cTc/cGc	-0,06	0	0	possibly_damaging	0,83	neutral	0,7	neutral	4,54	neutral	0,58	neutral	-1,99	neutral_impact	0	neutral	0,73	neutral	0,62	deleterious	2,87	21,7	0,47	0,55	neutral	0,39	disease	0,7	neutral	0,41	disease	0,53	1	neutral	0,8	neutral	0,44	neutral	-3	deleterious	0,74	low_impact	-1,4	medium_impact	0,44	low_impact	-1,2	0,55	0,8	25,37	15,03	N	0,22	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13426	13426	A	G	MI.21589	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1090	364	K	E	Aaa/Gaa	-3,5	0	0	probably_damaging	1	neutral	0,94	neutral	4,5	neutral	-2,68	deleterious	-3,23	medium_impact	2,79	neutral	0,78	damaging	0,2	deleterious	4,05	23,7	0,64	0,7	disease	0,7	disease	0,72	disease	0,56	disease	0,64	3	deleterious	1	deleterious	0,47	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,89	medium_impact	1,35	0,64	0,8	17,08	16,03	N	0,15	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6040	6040	A	G	MI.2159	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	137	46	N	S	aAc/aGc	-1,03	0	0,02	benign	0	neutral	1	neutral	2,88	neutral	-0,44	neutral	1,55	neutral_impact	-2,6	neutral	0,8	neutral	0,98	neutral	-1,19	0,01	0,64	0,65	neutral	0,18	neutral	0,05	neutral	0,19	neutral	0,21	6	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,07	high_impact	1,86	low_impact	-3,5	0,14	0,9	15,79	51,88	N	0,36	N	0,1	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13426	13426	A	C	MI.21590	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1090	364	K	Q	Aaa/Caa	-3,5	0	0	probably_damaging	1	neutral	0,69	neutral	4,51	neutral	-2,53	deleterious	-3,19	medium_impact	2,21	neutral	0,82	damaging	0,28	deleterious	3,46	23	0,73	0,75	disease	0,79	disease	0,56	neutral	0,36	disease	0,54	1	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,42	medium_impact	0,82	0,7	0,85	17,08	16,03	N	0,17	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13427	13427	A	C	MI.21591	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1091	364	K	T	aAa/aCa	2,46	0,81	0	probably_damaging	1	neutral	0,77	neutral	4,5	neutral	-2,81	deleterious	-4,87	low_impact	1,7	neutral	0,82	neutral	0,42	deleterious	2,6	20,2	0,48	0,55	disease	0,77	neutral	0,47	neutral	0,36	disease	0,63	3	deleterious	1	neutral	0,39	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,52	medium_impact	0,35	0,61	0,8	17,08	16,03	N	0,26	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13427	13427	A	T	MI.21592	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1091	364	K	M	aAa/aTa	2,46	0,81	0	probably_damaging	1	neutral	0,3	neutral	4,48	deleterious	-4,71	deleterious	-4,83	medium_impact	2,1	neutral	0,84	neutral	0,29	deleterious	4,01	23,6	0,4	0,5	disease	0,94	disease	0,57	neutral	0,37	disease	0,79	6	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,03	medium_impact	0,72	0,59	0,8	17,08	16,03	N	0,39	N	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13428	13428	A	C	MI.21593	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1092	364	K	N	aaA/aaC	3,61	0,83	0	probably_damaging	1	neutral	0,64	neutral	4,57	neutral	-2,77	deleterious	-3,84	low_impact	0,96	neutral	0,81	neutral	0,9	deleterious	2,4	18,8	0,79	0,8	disease	0,68	neutral	0,35	neutral	0,3	disease	0,64	3	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,37	medium_impact	-0,33	0,78	0,85	17,08	16,03	N	0,33	N	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13428	13428	A	T	MI.21594	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1092	364	K	N	aaA/aaT	3,61	0,83	0	probably_damaging	1	neutral	0,64	neutral	4,57	neutral	-2,77	deleterious	-3,84	low_impact	0,96	neutral	0,81	neutral	0,9	deleterious	2,43	19	0,79	0,8	disease	0,68	neutral	0,35	neutral	0,3	disease	0,64	3	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,37	medium_impact	-0,33	0,78	0,85	17,08	16,03	N	0,34	N	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13429	13429	A	C	MI.21595	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1093	365	T	P	Acc/Ccc	0,63	0,11	0	possibly_damaging	0,81	neutral	0,35	neutral	4,59	neutral	-2,3	neutral	-2,24	low_impact	1,22	neutral	0,81	neutral	0,98	neutral	1,78	14,85	0,23	0,45	disease	0,5	disease	0,65	neutral	0,46	neutral	0,47	1	neutral	0,83	neutral	0,27	neutral	-3	deleterious	0,53	low_impact	-1,34	medium_impact	0,08	medium_impact	-0,09	0,53	0,8	23,71	12,55	N	0,35	N	0,77	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13429	13429	A	T	MI.21596	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1093	365	T	S	Acc/Tcc	0,63	0,11	0	benign	0,32	neutral	0,8	neutral	4,71	neutral	0,06	neutral	-1,13	neutral_impact	-0,36	neutral	0,85	neutral	0,98	deleterious	0,1	3,56	0,55	0,6	neutral	0,41	neutral	0,21	neutral	0,27	neutral	0,37	3	neutral	0,21	deleterious	0,74	neutral	-6	neutral	0,21	medium_impact	-0,44	medium_impact	0,57	low_impact	-1,53	0,57	0,8	23,71	12,55	N	0,34	N	0,31	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13429	13429	A	G	MI.21597	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1093	365	T	A	Acc/Gcc	0,63	0,11	0	benign	0,02	neutral	0,78	neutral	4,64	neutral	-0,23	neutral	-1,1	neutral_impact	-0,07	neutral	0,84	neutral	1	neutral	-0,12	1,59	0,7	0,75	disease	0,52	neutral	0,17	neutral	0,29	neutral	0,26	5	neutral	0,17	deleterious	0,88	neutral	-6	neutral	0,12	medium_impact	0,86	medium_impact	0,54	low_impact	-1,27	0,52	0,8	23,71	12,55	N	0,33	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13430	13430	C	G	MI.21598	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1094	365	T	S	aCc/aGc	-6,94	0	0	benign	0,32	neutral	0,8	neutral	4,71	neutral	0,06	neutral	-1,13	neutral_impact	-0,36	neutral	0,85	neutral	0,98	deleterious	0,45	7,06	0,55	0,6	neutral	0,41	neutral	0,21	neutral	0,27	neutral	0,37	3	neutral	0,21	deleterious	0,74	neutral	-6	neutral	0,21	medium_impact	-0,44	medium_impact	0,57	low_impact	-1,53	0,57	0,8	23,71	12,55	N	0,29	N	0,31	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13430	13430	C	A	MI.21599	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1094	365	T	N	aCc/aAc	-6,94	0	0	possibly_damaging	0,85	neutral	0,52	neutral	4,63	neutral	-0,89	deleterious	-2,65	neutral_impact	0,6	neutral	0,82	neutral	0,69	deleterious	3,45	23	0,77	0,8	disease	0,64	neutral	0,43	neutral	0,45	disease	0,61	2	neutral	0,83	neutral	0,34	neutral	-3	deleterious	0,5	low_impact	-1,46	medium_impact	0,25	medium_impact	-0,66	0,71	0,85	23,71	12,55	N	0,25	N	0,63	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8627	8627	C	G	MI.216	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	101	34	S	C	tCc/tGc	0,59	0	0	probably_damaging	1	neutral	0,19	neutral	4,26	deleterious	-4,22	deleterious	-2,86	medium_impact	2,38	neutral	0,8	neutral	0,28	deleterious	3,43	23	0,38	0,65	disease	0,89	disease	0,65	neutral	0,36	disease	0,61	2	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,06	medium_impact	0,94	0,62	0,9	9,73	14,65	N	0,31	N	0,67	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6040	6040	A	T	MI.2160	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	137	46	N	I	aAc/aTc	-1,03	0	0,02	benign	0,09	deleterious	0,04	neutral	2,74	neutral	-2,25	neutral	-1,14	neutral_impact	0,4	neutral	0,73	neutral	0,73	deleterious	4,03	23,6	0,33	0,55	neutral	0,45	disease	0,52	neutral	0,36	neutral	0,5	0	neutral	0,96	deleterious	0,48	neutral	-2	neutral	0,22	medium_impact	0,19	medium_impact	-0,58	medium_impact	-0,73	0,27	0,9	15,79	51,88	N	0,47	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13430	13430	C	T	MI.21600	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1094	365	T	I	aCc/aTc	-6,94	0	0	benign	0,02	neutral	0,66	neutral	4,64	neutral	-1,11	deleterious	-2,56	neutral_impact	0,15	neutral	0,83	neutral	0,97	deleterious	0,34	6,04	0,66	0,7	disease	0,57	neutral	0,31	neutral	0,33	disease	0,59	2	neutral	0,3	deleterious	0,82	neutral	-6	neutral	0,15	medium_impact	0,86	medium_impact	0,39	low_impact	-1,07	0,68	0,85	23,71	12,55	N	0,3	N	0,16	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13432	13432	A	G	MI.21601	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1096	366	M	V	Ata/Gta	-20	0	0	benign	0,26	neutral	0,58	neutral	4,58	deleterious	-3,56	neutral	-2,15	medium_impact	2,26	neutral	0,8	neutral	0,66	neutral	1,04	10,87	0,52	0,6	disease	0,71	neutral	0,39	disease	0,71	disease	0,69	4	neutral	0,31	deleterious	0,66	neutral	-3	neutral	0,28	medium_impact	-0,32	medium_impact	0,31	medium_impact	0,86	0,5	0,8	3,98	9,82	N	0,27	N	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13432	13432	A	C	MI.21602	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1096	366	M	L	Ata/Cta	-20	0	0	benign	0,01	neutral	0,78	neutral	4,62	neutral	-1,9	neutral	-0,29	neutral_impact	-0,44	neutral	0,85	neutral	0,98	neutral	-1,2	0,01	0,58	0,65	disease	0,58	neutral	0,13	neutral	0,31	neutral	0,29	4	neutral	0,19	deleterious	0,89	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,54	low_impact	-1,61	0,61	0,8	3,98	9,82	N	0,31	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13432	13432	A	T	MI.21603	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1096	366	M	L	Ata/Tta	-20	0	0	benign	0,01	neutral	0,78	neutral	4,62	neutral	-1,9	neutral	-0,29	neutral_impact	-0,44	neutral	0,85	neutral	0,98	neutral	-1,02	0,02	0,58	0,65	disease	0,58	neutral	0,13	neutral	0,31	neutral	0,29	4	neutral	0,19	deleterious	0,89	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,54	low_impact	-1,61	0,61	0,8	3,98	9,82	N	0,32	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13433	13433	T	A	MI.21604	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1097	366	M	K	aTa/aAa	-4,19	0	0	possibly_damaging	0,71	neutral	0,48	neutral	4,52	deleterious	-4,25	deleterious	-4,43	medium_impact	3,15	neutral	0,8	neutral	0,42	deleterious	2,41	18,91	0,2	0,45	disease	0,8	disease	0,65	disease	0,76	disease	0,78	6	neutral	0,69	neutral	0,39	NA	0	deleterious	0,58	low_impact	-1,12	medium_impact	0,21	medium_impact	1,67	0,34	0,8	3,98	9,82	N	0,33	N	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13433	13433	T	C	MI.21605	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1097	366	M	T	aTa/aCa	-4,19	0	0	possibly_damaging	0,64	neutral	0,54	neutral	4,55	deleterious	-3,75	deleterious	-3,95	medium_impact	2	neutral	0,74	neutral	0,75	deleterious	0,02	2,82	0,48	0,55	disease	0,64	neutral	0,22	neutral	0,47	neutral	0,46	1	neutral	0,6	neutral	0,45	NA	0	neutral	0,41	medium_impact	-0,98	medium_impact	0,27	medium_impact	0,62	0,38	0,8	3,98	9,82	N	0,29	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13434	13434	A	C	MI.21606	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1098	366	M	I	atA/atC	4,29	0,47	0,02	benign	0,25	neutral	0,45	neutral	4,58	deleterious	-3,01	neutral	-1,67	medium_impact	2,07	neutral	0,77	neutral	0,72	neutral	1,64	14,07	0,52	0,6	disease	0,73	neutral	0,28	neutral	0,47	disease	0,58	2	neutral	0,46	deleterious	0,6	neutral	-3	neutral	0,28	medium_impact	-0,29	medium_impact	0,18	medium_impact	0,69	0,61	0,8	3,98	9,82	N	0,38	N	0,8	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13434	13434	A	T	MI.21607	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1098	366	M	I	atA/atT	4,29	0,47	0,02	benign	0,25	neutral	0,45	neutral	4,58	deleterious	-3,01	neutral	-1,67	medium_impact	2,07	neutral	0,77	neutral	0,72	neutral	1,73	14,56	0,52	0,6	disease	0,73	neutral	0,28	neutral	0,47	disease	0,58	2	neutral	0,46	deleterious	0,6	neutral	-3	neutral	0,28	medium_impact	-0,29	medium_impact	0,18	medium_impact	0,69	0,61	0,8	3,98	9,82	N	0,38	N	0,8	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13435	13435	C	G	MI.21608	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1099	367	P	A	Cct/Gct	-7,4	0	0	probably_damaging	1	neutral	0,53	neutral	4,29	deleterious	-5,76	deleterious	-7,19	high_impact	4,57	damaging	0,4	damaging	0,16	deleterious	3,15	22,6	0,3	0,45	disease	0,86	disease	0,56	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,26	high_impact	2,97	0,58	0,8	27,03	7,15	N	0,52	P	0,73	polymorphism	0,81	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13435	13435	C	T	MI.21609	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1099	367	P	S	Cct/Tct	-7,4	0	0	probably_damaging	1	neutral	0,45	neutral	4,26	deleterious	-5,65	deleterious	-7,19	medium_impact	3,29	damaging	0,47	damaging	0,16	deleterious	3,98	23,6	0,47	0,55	disease	0,88	disease	0,75	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,18	medium_impact	1,8	0,24	0,8	27,03	7,15	N	0,3	N	0,78	polymorphism	0,73	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6041	6041	C	G	MI.2161	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	138	46	N	K	aaC/aaG	2,44	0,01	0	benign	0,06	neutral	0,06	neutral	2,83	neutral	-1,08	neutral	-0,38	neutral_impact	0,26	neutral	0,65	neutral	0,54	deleterious	2,12	16,99	0,65	0,7	neutral	0,23	neutral	0,49	neutral	0,4	disease	0,51	0	neutral	0,94	deleterious	0,5	neutral	-6	neutral	0,17	medium_impact	0,37	medium_impact	-0,47	medium_impact	-0,86	0,39	0,9	15,79	51,88	N	0,5	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13435	13435	C	A	MI.21610	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1099	367	P	T	Cct/Act	-7,4	0	0	probably_damaging	1	neutral	0,42	neutral	4,25	deleterious	-6,1	deleterious	-7,19	high_impact	4,22	damaging	0,37	damaging	0,13	deleterious	3,78	23,4	0,37	0,5	disease	0,84	disease	0,72	disease	0,75	disease	0,79	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,16	high_impact	2,65	0,63	0,8	27,03	7,15	N	0,45	N	0,91	polymorphism	0,74	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13436	13436	C	G	MI.21611	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1100	367	P	R	cCt/cGt	5,44	1	0	probably_damaging	1	neutral	0,36	neutral	4,29	deleterious	-5,31	deleterious	-8,09	high_impact	3,84	damaging	0,44	damaging	0,13	deleterious	3,62	23,2	0,28	0,45	disease	0,9	disease	0,84	disease	0,86	disease	0,85	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,1	high_impact	2,31	0,5	0,8	27,03	7,15	P	0,66	P	0,64	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13436	13436	C	T	MI.21612	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1100	367	P	L	cCt/cTt	5,44	1	0	probably_damaging	1	neutral	0,7	neutral	4,24	deleterious	-6,39	deleterious	-8,99	high_impact	4,08	damaging	0,34	damaging	0,11	deleterious	4,33	24	0,41	0,5	disease	0,83	disease	0,8	disease	0,74	disease	0,78	6	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,44	high_impact	2,52	0,77	0,85	27,03	7,15	P	0,62	P	0,97	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13436	13436	C	A	MI.21613	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1100	367	P	H	cCt/cAt	5,44	1	0	probably_damaging	1	neutral	0,55	neutral	4,22	deleterious	-7,39	deleterious	-8,09	high_impact	5,12	damaging	0,41	damaging	0,11	deleterious	4,11	23,7	0,29	0,45	disease	0,95	disease	0,8	disease	0,83	disease	0,86	7	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,28	high_impact	3,47	0,55	0,8	27,03	7,15	P	0,67	P	0,72	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13438	13438	C	A	MI.21614	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1102	368	L	I	Ctc/Atc	-5,56	0	0	possibly_damaging	0,81	neutral	0,51	neutral	4,69	neutral	-0,24	neutral	-0,23	neutral_impact	-0,48	neutral	0,83	neutral	0,95	deleterious	2,64	20,5	0,57	0,65	neutral	0,43	neutral	0,12	neutral	0,15	neutral	0,31	4	neutral	0,79	neutral	0,35	neutral	-3	deleterious	0,66	low_impact	-1,34	medium_impact	0,24	low_impact	-1,64	0,8	0,85	28,03	18,12	N	0,42	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13438	13438	C	T	MI.21615	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1102	368	L	F	Ctc/Ttc	-5,56	0	0	benign	0,17	neutral	0,86	neutral	4,54	neutral	-1,19	neutral	2,09	neutral_impact	0,02	neutral	0,82	neutral	0,98	neutral	1,27	12,12	0,64	0,7	neutral	0,35	neutral	0,06	neutral	0,14	neutral	0,2	6	neutral	0,08	deleterious	0,85	neutral	-6	deleterious	0,65	medium_impact	-0,09	medium_impact	0,67	low_impact	-1,18	0,71	0,85	28,03	18,12	N	0,33	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13438	13438	C	G	MI.21616	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1102	368	L	V	Ctc/Gtc	-5,56	0	0	possibly_damaging	0,86	neutral	0,59	neutral	4,55	neutral	0	neutral	-1,03	neutral_impact	0,39	neutral	0,78	neutral	0,87	deleterious	3,41	23	0,56	0,6	neutral	0,4	neutral	0,19	neutral	0,19	neutral	0,38	2	neutral	0,84	neutral	0,37	neutral	-3	deleterious	0,66	low_impact	-1,5	medium_impact	0,32	medium_impact	-0,85	0,61	0,8	28,03	18,12	N	0,35	N	0,19	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13439	13439	T	A	MI.21617	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1103	368	L	H	cTc/cAc	-0,06	0	0	probably_damaging	0,99	neutral	0,56	neutral	4,43	deleterious	-4,14	deleterious	-2,6	medium_impact	2,64	neutral	0,76	neutral	0,56	deleterious	4,09	23,7	0,38	0,5	disease	0,91	neutral	0,49	disease	0,52	disease	0,65	3	deleterious	0,99	neutral	0,29	deleterious	1	deleterious	0,81	low_impact	-2,64	medium_impact	0,29	medium_impact	1,21	0,67	0,85	28,03	18,12	N	0,26	N	0,71	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13439	13439	T	C	MI.21618	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1103	368	L	P	cTc/cCc	-0,06	0	0	probably_damaging	0,99	neutral	0,31	neutral	4,42	deleterious	-4,58	deleterious	-4,17	medium_impact	2,56	damaging	0,6	neutral	0,43	deleterious	3,93	23,5	0,24	0,45	disease	0,87	disease	0,74	disease	0,68	disease	0,8	6	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,87	low_impact	-2,64	medium_impact	0,04	medium_impact	1,14	0,59	0,8	28,03	18,12	N	0,26	N	0,89	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13439	13439	T	G	MI.21619	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1103	368	L	R	cTc/cGc	-0,06	0	0	probably_damaging	0,98	neutral	0,35	neutral	4,43	neutral	-2,41	deleterious	-3,4	medium_impact	2,48	neutral	0,7	neutral	0,51	deleterious	4,21	23,9	0,26	0,45	disease	0,76	disease	0,72	disease	0,68	disease	0,75	5	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,84	low_impact	-2,35	medium_impact	0,08	medium_impact	1,06	0,6	0,8	28,03	18,12	N	0,27	N	0,79	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6041	6041	C	A	MI.2162	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	138	46	N	K	aaC/aaA	2,44	0,01	0	benign	0,06	neutral	0,06	neutral	2,83	neutral	-1,08	neutral	-0,38	neutral_impact	0,26	neutral	0,65	neutral	0,54	deleterious	2,6	20,2	0,65	0,7	neutral	0,23	neutral	0,49	neutral	0,4	disease	0,51	0	neutral	0,94	deleterious	0,5	neutral	-6	neutral	0,17	medium_impact	0,37	medium_impact	-0,47	medium_impact	-0,86	0,39	0,9	15,79	51,88	N	0,5	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13441	13441	A	G	MI.21620	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1105	369	T	A	Act/Gct	-5,33	0	0	probably_damaging	1	neutral	0,54	neutral	4,59	neutral	-2,75	deleterious	-4,49	medium_impact	3,33	neutral	0,61	damaging	0,13	deleterious	3,52	23,1	0,56	0,6	disease	0,74	neutral	0,46	disease	0,7	disease	0,6	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,27	medium_impact	1,84	0,6	0,8	29,35	7,21	N	0,24	N	0,69	polymorphism	0,97	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13441	13441	A	C	MI.21621	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1105	369	T	P	Act/Cct	-5,33	0	0	probably_damaging	1	neutral	0,22	neutral	4,51	deleterious	-5,82	deleterious	-5,39	high_impact	3,63	neutral	0,61	damaging	0,12	deleterious	3,5	23,1	0,25	0,45	disease	0,87	disease	0,71	disease	0,81	disease	0,83	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	-0,07	high_impact	2,11	0,65	0,8	29,35	7,21	N	0,31	N	0,97	polymorphism	0,86	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13441	13441	A	T	MI.21622	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1105	369	T	S	Act/Tct	-5,33	0	0	probably_damaging	1	neutral	0,45	neutral	4,59	deleterious	-3,62	deleterious	-3,59	medium_impact	2,19	damaging	0,53	damaging	0,21	deleterious	3,33	22,9	0,44	0,55	disease	0,86	disease	0,54	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,18	medium_impact	0,8	0,68	0,85	29,35	7,21	N	0,28	N	0,89	polymorphism	0,99	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13442	13442	C	A	MI.21623	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1106	369	T	N	aCt/aAt	6,81	1	0	probably_damaging	1	neutral	0,33	neutral	4,52	deleterious	-6	deleterious	-4,49	high_impact	4,22	damaging	0,5	damaging	0,11	deleterious	3,68	23,3	0,44	0,55	disease	0,94	disease	0,68	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,06	high_impact	2,65	0,81	0,85	29,35	7,21	P	0,54	P	0,93	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13442	13442	C	T	MI.21624	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1106	369	T	I	aCt/aTt	6,81	1	0	probably_damaging	1	neutral	0,41	neutral	4,65	deleterious	-3,16	deleterious	-5,39	medium_impact	3,14	damaging	0,55	damaging	0,11	deleterious	3,93	23,5	0,47	0,55	disease	0,66	disease	0,7	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,15	medium_impact	1,67	0,76	0,85	29,35	7,21	N	0,47	N	0,95	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13442	13442	C	G	MI.21625	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1106	369	T	S	aCt/aGt	6,81	1	0	probably_damaging	1	neutral	0,45	neutral	4,59	deleterious	-3,62	deleterious	-3,59	medium_impact	2,19	damaging	0,53	damaging	0,21	deleterious	3,56	23,1	0,44	0,55	disease	0,86	disease	0,54	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,18	medium_impact	0,8	0,68	0,85	29,35	7,21	P	0,52	P	0,89	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13444	13444	T	G	MI.21626	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1108	370	S	A	Tca/Gca	-6,48	0	0	benign	0,18	neutral	0,54	neutral	4,78	neutral	1,95	neutral	-1,61	neutral_impact	0,69	neutral	0,8	neutral	0,86	deleterious	2,63	20,4	0,62	0,65	neutral	0,34	neutral	0,29	neutral	0,45	neutral	0,45	1	neutral	0,35	deleterious	0,68	neutral	-6	deleterious	0,68	medium_impact	-0,12	medium_impact	0,27	medium_impact	-0,57	0,71	0,85	16,75	19,08	N	0,3	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13444	13444	T	A	MI.21627	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1108	370	S	T	Tca/Aca	-6,48	0	0	benign	0,26	neutral	0,55	neutral	4,63	neutral	-0,72	neutral	-0,02	neutral_impact	0,69	neutral	0,79	neutral	0,96	deleterious	2,18	17,39	0,43	0,55	neutral	0,43	neutral	0,09	neutral	0,35	neutral	0,28	5	neutral	0,34	deleterious	0,65	neutral	-6	deleterious	0,68	medium_impact	-0,32	medium_impact	0,28	medium_impact	-0,57	0,82	0,85	16,75	19,08	N	0,36	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13444	13444	T	C	MI.21628	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1108	370	S	P	Tca/Cca	-6,48	0	0	probably_damaging	0,97	neutral	0,23	neutral	4,54	deleterious	-3,41	deleterious	-3,22	medium_impact	3,5	damaging	0,59	damaging	0,18	deleterious	4,01	23,6	0,29	0,45	disease	0,51	disease	0,8	disease	0,76	disease	0,76	5	neutral	0,98	neutral	0,13	deleterious	1	deleterious	0,79	low_impact	-2,18	medium_impact	-0,06	medium_impact	1,99	0,74	0,85	16,75	19,08	N	0,32	N	0,95	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13445	13445	C	T	MI.21629	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1109	370	S	L	tCa/tTa	0,17	0	0	possibly_damaging	0,81	neutral	0,8	neutral	4,61	neutral	-1,05	deleterious	-3,7	medium_impact	2,35	neutral	0,68	damaging	0,18	deleterious	4,63	24,5	0,43	0,55	disease	0,69	disease	0,71	disease	0,62	disease	0,67	3	neutral	0,78	deleterious	0,5	NA	0	deleterious	0,77	low_impact	-1,34	medium_impact	0,57	medium_impact	0,94	0,87	0,9	16,75	19,08	N	0,17	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6042	6042	C	A	MI.2163	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	139	47	L	I	Ctt/Att	-11,21	0	0	benign	0,31	deleterious	0,04	neutral	2,72	neutral	-2,79	neutral	-0,87	medium_impact	2,27	damaging	0,59	damaging	0,09	deleterious	4,12	23,8	0,42	0,55	neutral	0,41	disease	0,59	neutral	0,24	neutral	0,45	1	neutral	0,95	neutral	0,37	deleterious	1	neutral	0,3	medium_impact	-0,43	medium_impact	-0,58	medium_impact	1	0,55	0,9	2,92	7,3	N	0,34	N	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13445	13445	C	G	MI.21630	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1109	370	S	W	tCa/tGa	0,17	0	0	probably_damaging	1	neutral	0,19	neutral	4,53	neutral	-2,81	deleterious	-4,66	medium_impact	2,9	neutral	0,7	damaging	0,18	deleterious	4,38	24,1	0,23	0,45	disease	0,85	disease	0,78	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	-0,12	medium_impact	1,45	0,46	0,8	16,75	19,08	N	0,25	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13447	13447	A	C	MI.21631	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1111	371	T	P	Acc/Ccc	-7,4	0	0	probably_damaging	0,92	neutral	0,2	neutral	4,48	deleterious	-3,49	deleterious	-2,91	medium_impact	3,12	neutral	0,63	neutral	0,33	deleterious	3,99	23,6	0,22	0,45	disease	0,85	disease	0,82	disease	0,73	disease	0,82	6	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,86	low_impact	-1,75	medium_impact	-0,1	medium_impact	1,65	0,64	0,8	17,25	12,94	N	0,27	N	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13447	13447	A	T	MI.21632	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1111	371	T	S	Acc/Tcc	-7,4	0	0	benign	0,12	neutral	0,53	neutral	4,55	neutral	-0,88	neutral	0,72	neutral_impact	-0,38	neutral	0,8	neutral	0,95	neutral	1,13	11,36	0,56	0,6	disease	0,54	neutral	0,06	neutral	0,28	neutral	0,27	5	neutral	0,38	deleterious	0,71	neutral	-6	deleterious	0,67	medium_impact	0,08	medium_impact	0,26	low_impact	-1,55	0,67	0,85	17,25	12,94	N	0,35	N	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13447	13447	A	G	MI.21633	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1111	371	T	A	Acc/Gcc	-7,4	0	0	benign	0,08	neutral	0,5	neutral	4,59	neutral	0,81	neutral	-1,37	neutral_impact	-0,02	neutral	0,75	neutral	0,76	deleterious	3,95	23,6	0,74	0,75	neutral	0,48	neutral	0,26	neutral	0,43	neutral	0,42	2	neutral	0,44	deleterious	0,71	neutral	-6	deleterious	0,7	medium_impact	0,26	medium_impact	0,23	low_impact	-1,22	0,48	0,8	17,25	12,94	N	0,29	N	0,63	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13448	13448	C	A	MI.21634	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1112	371	T	N	aCc/aAc	-0,06	0	0	possibly_damaging	0,87	neutral	0,28	neutral	4,51	deleterious	-3,59	neutral	-1,42	medium_impact	3,47	neutral	0,73	neutral	0,53	deleterious	3,82	23,4	0,48	0,55	disease	0,86	disease	0,66	disease	0,54	disease	0,66	3	neutral	0,89	neutral	0,21	NA	0	deleterious	0,8	low_impact	-1,53	medium_impact	0,01	medium_impact	1,97	0,79	0,85	17,25	12,94	N	0,37	N	0,54	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13448	13448	C	T	MI.21635	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1112	371	T	I	aCc/aTc	-0,06	0	0	possibly_damaging	0,9	neutral	0,48	neutral	4,6	neutral	0,33	deleterious	-3,52	low_impact	0,84	neutral	0,84	neutral	0,56	deleterious	3,95	23,6	0,49	0,55	neutral	0,47	disease	0,58	disease	0,6	disease	0,53	1	neutral	0,89	neutral	0,29	neutral	-3	deleterious	0,73	low_impact	-1,65	medium_impact	0,21	medium_impact	-0,44	0,75	0,85	17,25	12,94	N	0,23	N	0,96	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13448	13448	C	G	MI.21636	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1112	371	T	S	aCc/aGc	-0,06	0	0	benign	0,12	neutral	0,53	neutral	4,55	neutral	-0,88	neutral	0,72	neutral_impact	-0,38	neutral	0,8	neutral	0,95	deleterious	0,79	9,38	0,56	0,6	disease	0,54	neutral	0,06	neutral	0,28	neutral	0,27	5	neutral	0,38	deleterious	0,71	neutral	-6	deleterious	0,67	medium_impact	0,08	medium_impact	0,26	low_impact	-1,55	0,67	0,85	17,25	12,94	N	0,35	N	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13450	13450	T	A	MI.21637	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1114	372	S	T	Tcc/Acc	-11,29	0	0	possibly_damaging	0,86	neutral	0,53	neutral	4,65	neutral	1,1	neutral	-1,66	neutral_impact	-0,44	neutral	0,85	neutral	0,8	deleterious	2,79	21,3	0,45	0,55	neutral	0,41	neutral	0,21	neutral	0,48	neutral	0,4	2	neutral	0,84	neutral	0,34	neutral	-3	deleterious	0,67	low_impact	-1,5	medium_impact	0,26	low_impact	-1,61	0,76	0,85	22,55	15,56	N	0,29	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13450	13450	T	G	MI.21638	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1114	372	S	A	Tcc/Gcc	-11,29	0	0	benign	0,12	neutral	0,62	neutral	4,68	neutral	1,63	neutral	-0,33	neutral_impact	-0,68	neutral	0,84	neutral	0,99	neutral	1,54	13,53	0,51	0,6	neutral	0,35	neutral	0,14	neutral	0,35	neutral	0,29	4	neutral	0,28	deleterious	0,75	neutral	-6	deleterious	0,67	medium_impact	0,08	medium_impact	0,35	low_impact	-1,82	0,71	0,85	22,55	15,56	N	0,38	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13450	13450	T	C	MI.21639	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1114	372	S	P	Tcc/Ccc	-11,29	0	0	probably_damaging	0,98	neutral	0,23	neutral	4,52	neutral	-2,91	deleterious	-3,1	medium_impact	2,2	damaging	0,52	neutral	0,36	deleterious	4,03	23,7	0,18	0,45	disease	0,88	disease	0,8	disease	0,67	disease	0,82	6	deleterious	0,98	neutral	0,13	deleterious	1	deleterious	0,87	low_impact	-2,35	medium_impact	-0,06	medium_impact	0,81	0,68	0,85	22,55	15,56	N	0,28	N	0,85	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6042	6042	C	T	MI.2164	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	139	47	L	F	Ctt/Ttt	-11,21	0	0	benign	0,02	neutral	0,18	neutral	2,87	neutral	-2,39	neutral	-1,21	low_impact	1,02	damaging	0,55	damaging	0,09	deleterious	2,54	19,7	0,39	0,55	neutral	0,32	neutral	0,42	neutral	0,21	neutral	0,45	1	neutral	0,81	deleterious	0,58	neutral	-6	neutral	0,21	medium_impact	0,83	medium_impact	-0,17	medium_impact	-0,16	0,4	0,9	2,92	7,3	N	0,4	N	0,87	polymorphism	1	0,02	rs878930535	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13451	13451	C	T	MI.21640	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1115	372	S	F	tCc/tTc	0,86	0,02	0	probably_damaging	0,98	neutral	0,78	neutral	4,55	neutral	0,04	deleterious	-3,82	neutral_impact	0,15	neutral	0,72	neutral	0,75	deleterious	4,29	24	0,33	0,5	disease	0,57	disease	0,61	disease	0,57	disease	0,54	1	neutral	0,97	neutral	0,4	neutral	-2	deleterious	0,75	low_impact	-2,35	medium_impact	0,54	low_impact	-1,07	0,53	0,8	22,55	15,56	N	0,23	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13451	13451	C	A	MI.21641	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1115	372	S	Y	tCc/tAc	0,86	0,02	0	probably_damaging	0,98	neutral	1	neutral	4,55	neutral	-2,07	deleterious	-3,79	neutral_impact	0,5	neutral	0,77	neutral	0,78	deleterious	2,98	22,2	0,25	0,45	disease	0,75	disease	0,53	disease	0,52	disease	0,55	1	deleterious	0,98	deleterious	0,51	neutral	-2	deleterious	0,78	low_impact	-2,35	high_impact	1,89	medium_impact	-0,75	0,77	0,85	22,55	15,56	N	0,21	N	0,85	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13451	13451	C	G	MI.21642	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1115	372	S	C	tCc/tGc	0,86	0,02	0	benign	0,33	neutral	0,22	neutral	4,6	neutral	-0,08	neutral	-1,64	neutral_impact	-1,68	neutral	0,77	neutral	0,95	neutral	0,93	10,28	0,3	0,45	neutral	0,43	neutral	0,12	neutral	0,22	neutral	0,3	4	neutral	0,74	neutral	0,45	neutral	-6	deleterious	0,66	medium_impact	-0,45	medium_impact	-0,07	low_impact	-2,74	0,63	0,8	22,55	15,56	N	0,41	N	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13453	13453	C	G	MI.21643	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1117	373	L	V	Ctc/Gtc	-4,87	0	0	possibly_damaging	0,9	neutral	0,52	neutral	4,29	neutral	-1,15	deleterious	-2,5	medium_impact	2,17	neutral	0,81	neutral	0,57	deleterious	3,47	23	0,36	0,5	disease	0,68	neutral	0,4	disease	0,52	disease	0,63	3	neutral	0,89	neutral	0,31	NA	0	deleterious	0,73	low_impact	-1,65	medium_impact	0,25	medium_impact	0,78	0,68	0,85	6,8	9,93	N	0,25	N	0,59	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13453	13453	C	A	MI.21644	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1117	373	L	I	Ctc/Atc	-4,87	0	0	possibly_damaging	0,9	neutral	0,44	neutral	4,37	neutral	-1,38	neutral	-1,63	neutral_impact	0,44	neutral	0,81	neutral	0,91	deleterious	3,06	22,4	0,33	0,5	disease	0,53	neutral	0,28	neutral	0,38	neutral	0,39	2	neutral	0,89	neutral	0,27	neutral	-3	deleterious	0,7	low_impact	-1,65	medium_impact	0,18	medium_impact	-0,8	0,8	0,85	6,8	9,93	N	0,3	N	0,55	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13453	13453	C	T	MI.21645	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1117	373	L	F	Ctc/Ttc	-4,87	0	0	probably_damaging	0,98	neutral	0,77	neutral	4,41	neutral	1,48	deleterious	-3,47	neutral_impact	-0,28	neutral	0,74	neutral	0,78	deleterious	2,92	21,9	0,39	0,5	neutral	0,35	neutral	0,41	neutral	0,41	neutral	0,44	1	neutral	0,98	neutral	0,4	neutral	-2	deleterious	0,68	low_impact	-2,35	medium_impact	0,52	low_impact	-1,46	0,66	0,8	6,8	9,93	N	0,28	N	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13454	13454	T	G	MI.21646	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1118	373	L	R	cTc/cGc	-1,89	0	0	probably_damaging	0,98	neutral	0,35	neutral	4,2	deleterious	-4,17	deleterious	-5,27	high_impact	3,65	neutral	0,63	neutral	0,31	deleterious	4,23	23,9	0,08	0,35	disease	0,9	disease	0,8	disease	0,72	disease	0,79	6	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,87	low_impact	-2,35	medium_impact	0,08	high_impact	2,13	0,54	0,8	6,8	9,93	N	0,29	N	0,98	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13454	13454	T	A	MI.21647	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1118	373	L	H	cTc/cAc	-1,89	0	0	probably_damaging	1	neutral	0,54	neutral	4,19	deleterious	-4,65	deleterious	-6,14	high_impact	3,65	neutral	0,71	neutral	0,36	deleterious	4,15	23,8	0,09	0,4	disease	0,93	disease	0,68	disease	0,69	disease	0,79	6	deleterious	0,99	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,27	high_impact	2,13	0,65	0,8	6,8	9,93	N	0,27	N	0,85	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13454	13454	T	C	MI.21648	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1118	373	L	P	cTc/cCc	-1,89	0	0	probably_damaging	1	neutral	0,28	neutral	4,19	deleterious	-4,33	deleterious	-6,14	high_impact	3,65	neutral	0,6	neutral	0,31	deleterious	3,94	23,5	0,08	0,35	disease	0,93	disease	0,78	disease	0,71	disease	0,81	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,01	high_impact	2,13	0,51	0,8	6,8	9,93	N	0,3	N	0,92	polymorphism	0,99	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13456	13456	A	G	MI.21649	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1120	374	T	A	Acc/Gcc	-4,87	0	0	benign	0,01	neutral	0,53	neutral	4,66	neutral	0,1	neutral	-1,22	low_impact	1,25	neutral	0,78	neutral	0,79	deleterious	0,49	7,39	0,61	0,65	neutral	0,37	neutral	0,38	disease	0,59	neutral	0,49	0	neutral	0,46	deleterious	0,76	neutral	-6	neutral	0,11	medium_impact	1,15	medium_impact	0,26	medium_impact	-0,06	0,37	0,8	18,91	13,61	N	0,27	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6042	6042	C	G	MI.2165	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	139	47	L	V	Ctt/Gtt	-11,21	0	0	benign	0,14	deleterious	0,04	neutral	2,73	neutral	-2,78	neutral	-1,44	medium_impact	2,49	damaging	0,59	damaging	0,05	deleterious	3,29	22,8	0,43	0,55	neutral	0,38	disease	0,61	neutral	0,38	neutral	0,46	1	neutral	0,96	neutral	0,45	deleterious	1	neutral	0,25	medium_impact	-0,01	medium_impact	-0,58	medium_impact	1,2	0,4	0,9	2,92	7,3	N	0,3	N	0,66	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13456	13456	A	C	MI.21650	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1120	374	T	P	Acc/Ccc	-4,87	0	0	possibly_damaging	0,55	neutral	0,22	neutral	4,56	deleterious	-4,19	deleterious	-2,69	medium_impact	3,46	neutral	0,69	neutral	0,44	deleterious	3,19	22,7	0,21	0,45	disease	0,89	disease	0,78	disease	0,73	disease	0,8	6	neutral	0,77	neutral	0,34	NA	0	deleterious	0,69	medium_impact	-0,83	medium_impact	-0,07	medium_impact	1,96	0,55	0,8	18,91	13,61	N	0,32	N	0,83	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13456	13456	A	T	MI.21651	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1120	374	T	S	Acc/Tcc	-4,87	0	0	benign	0,18	neutral	0,64	neutral	4,66	neutral	-1,46	neutral	-1,6	low_impact	1,38	neutral	0,75	neutral	0,79	neutral	1,53	13,45	0,46	0,55	neutral	0,46	neutral	0,46	disease	0,59	neutral	0,49	0	neutral	0,24	deleterious	0,73	neutral	-6	neutral	0,29	medium_impact	-0,12	medium_impact	0,37	medium_impact	0,06	0,62	0,8	18,91	13,61	N	0,3	N	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13457	13457	C	G	MI.21652	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1121	374	T	S	aCc/aGc	3,15	0,03	0	benign	0,18	neutral	0,64	neutral	4,66	neutral	-1,46	neutral	-1,6	low_impact	1,38	neutral	0,75	neutral	0,79	neutral	1,73	14,55	0,46	0,55	neutral	0,46	neutral	0,46	disease	0,59	neutral	0,49	0	neutral	0,24	deleterious	0,73	neutral	-6	neutral	0,29	medium_impact	-0,12	medium_impact	0,37	medium_impact	0,06	0,62	0,8	18,91	13,61	N	0,33	N	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13457	13457	C	A	MI.21653	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1121	374	T	N	aCc/aAc	3,15	0,03	0	possibly_damaging	0,62	neutral	0,34	neutral	4,59	deleterious	-3,04	deleterious	-2,52	low_impact	1,6	neutral	0,73	neutral	0,62	deleterious	3,49	23,1	0,46	0,55	disease	0,74	disease	0,62	disease	0,63	disease	0,61	2	neutral	0,7	neutral	0,36	neutral	-3	deleterious	0,63	medium_impact	-0,95	medium_impact	0,07	medium_impact	0,26	0,8	0,85	18,91	13,61	N	0,31	N	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13457	13457	C	T	MI.21654	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1121	374	T	I	aCc/aTc	3,15	0,03	0	benign	0,01	neutral	0,64	neutral	4,77	neutral	-0,35	neutral	1,19	neutral_impact	0,66	neutral	0,83	neutral	0,97	deleterious	0	2,62	0,46	0,55	neutral	0,43	neutral	0,43	neutral	0,42	neutral	0,45	1	neutral	0,34	deleterious	0,82	neutral	-6	neutral	0,13	medium_impact	1,15	medium_impact	0,37	medium_impact	-0,6	0,68	0,85	18,91	13,61	N	0,32	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13459	13459	A	C	MI.21655	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1123	375	I	L	Att/Ctt	-9,46	0	0	possibly_damaging	0,61	neutral	0,74	neutral	4,65	neutral	-0,86	neutral	-1,73	neutral_impact	0,66	neutral	0,74	neutral	0,72	deleterious	2,67	20,6	0,39	0,5	neutral	0,41	neutral	0,3	neutral	0,39	neutral	0,42	2	neutral	0,53	deleterious	0,57	neutral	-3	deleterious	0,64	medium_impact	-0,93	medium_impact	0,48	medium_impact	-0,6	0,64	0,8	13,1	12,86	N	0,29	N	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13459	13459	A	G	MI.21656	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1123	375	I	V	Att/Gtt	-9,46	0	0	benign	0,12	neutral	0,53	neutral	4,56	neutral	-0,84	neutral	-0,59	low_impact	1,07	neutral	0,86	neutral	0,97	deleterious	1,88	15,46	0,5	0,6	neutral	0,49	neutral	0,17	neutral	0,45	neutral	0,24	5	neutral	0,38	deleterious	0,71	neutral	-6	deleterious	0,62	medium_impact	0,08	medium_impact	0,26	medium_impact	-0,23	0,55	0,8	13,1	12,86	N	0,35	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13459	13459	A	T	MI.21657	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1123	375	I	F	Att/Ttt	-9,46	0	0	probably_damaging	0,97	neutral	0,75	neutral	4,43	neutral	-2,7	deleterious	-3,49	medium_impact	2,91	neutral	0,63	neutral	0,37	deleterious	4,09	23,7	0,33	0,5	disease	0,72	disease	0,6	disease	0,68	disease	0,66	3	neutral	0,97	neutral	0,39	deleterious	1	deleterious	0,75	low_impact	-2,18	medium_impact	0,5	medium_impact	1,46	0,75	0,85	13,1	12,86	N	0,21	N	0,86	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13460	13460	T	A	MI.21658	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1124	375	I	N	aTt/aAt	0,86	0,1	0	probably_damaging	0,98	neutral	0,34	neutral	4,33	deleterious	-5,95	deleterious	-5,9	high_impact	4,47	neutral	0,64	neutral	0,41	deleterious	4,41	24,1	0,24	0,45	disease	0,93	disease	0,67	disease	0,68	disease	0,79	6	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-2,35	medium_impact	0,07	high_impact	2,88	0,52	0,8	13,1	12,86	N	0,49	N	0,98	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13460	13460	T	G	MI.21659	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1124	375	I	S	aTt/aGt	0,86	0,1	0	probably_damaging	0,96	neutral	0,5	neutral	4,38	deleterious	-4,39	deleterious	-5	medium_impact	3,44	neutral	0,67	neutral	0,46	deleterious	4,34	24	0,28	0,45	disease	0,78	disease	0,7	disease	0,65	disease	0,66	3	neutral	0,95	neutral	0,27	deleterious	1	deleterious	0,78	low_impact	-2,06	medium_impact	0,23	medium_impact	1,94	0,5	0,8	13,1	12,86	N	0,34	N	0,9	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6043	6043	T	C	MI.2166	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	140	47	L	P	cTt/cCt	-0,11	0	0	probably_damaging	0,96	deleterious	0	neutral	2,59	deleterious	-5,45	deleterious	-3,74	high_impact	3,84	damaging	0,52	damaging	0,07	deleterious	3,67	23,3	0,22	0,55	disease	0,84	disease	0,9	neutral	0,42	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,88	low_impact	-2,06	low_impact	-1,48	high_impact	2,45	0,34	0,9	2,92	7,3	N	0,33	N	0,83	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13460	13460	T	C	MI.21660	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1124	375	I	T	aTt/aCt	0,86	0,1	0	probably_damaging	0,91	neutral	0,52	neutral	4,4	deleterious	-3,68	deleterious	-3,87	medium_impact	1,96	neutral	0,76	neutral	0,94	deleterious	2,23	17,74	0,42	0,5	disease	0,78	neutral	0,43	disease	0,59	disease	0,64	3	neutral	0,9	neutral	0,31	deleterious	1	deleterious	0,75	low_impact	-1,7	medium_impact	0,25	medium_impact	0,59	0,54	0,8	13,1	12,86	N	0,34	N	0,82	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13461	13461	T	G	MI.21661	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1125	375	I	M	atT/atG	3,61	0,39	0,01	probably_damaging	0,97	neutral	0,25	neutral	4,38	deleterious	-3,64	neutral	-2,48	medium_impact	2,64	neutral	0,75	neutral	0,47	deleterious	3,44	23	0,37	0,5	disease	0,67	neutral	0,46	disease	0,59	disease	0,63	3	neutral	0,98	neutral	0,14	deleterious	1	deleterious	0,72	low_impact	-2,18	medium_impact	-0,03	medium_impact	1,21	0,73	0,85	13,1	12,86	N	0,36	N	0,69	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13461	13461	T	A	MI.21662	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1125	375	I	M	atT/atA	3,61	0,39	0,01	probably_damaging	0,97	neutral	0,25	neutral	4,38	deleterious	-3,64	neutral	-2,48	medium_impact	2,64	neutral	0,75	neutral	0,47	deleterious	3,69	23,3	0,37	0,5	disease	0,67	neutral	0,46	disease	0,59	disease	0,63	3	neutral	0,98	neutral	0,14	deleterious	1	deleterious	0,72	low_impact	-2,18	medium_impact	-0,03	medium_impact	1,21	0,73	0,85	13,1	12,86	N	0,36	N	0,69	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13462	13462	G	C	MI.21663	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1126	376	G	R	Ggc/Cgc	-6,02	0	0	probably_damaging	0,97	neutral	0,35	neutral	4,54	deleterious	-5,55	deleterious	-7,21	high_impact	4,61	damaging	0,56	damaging	0,22	deleterious	3,87	23,5	0,06	0,35	disease	0,9	disease	0,83	disease	0,78	disease	0,84	7	neutral	0,97	neutral	0,19	deleterious	2	deleterious	0,86	low_impact	-2,18	medium_impact	0,08	high_impact	3,01	0,64	0,8	19,24	7,09	N	0,48	N	0,97	polymorphism	0,7	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13462	13462	G	A	MI.21664	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1126	376	G	S	Ggc/Agc	-6,02	0	0	benign	0,42	neutral	0,41	neutral	4,6	deleterious	-3,06	deleterious	-5,4	low_impact	1,46	damaging	0,49	neutral	0,48	deleterious	2,43	19	0,21	0,45	disease	0,56	disease	0,71	disease	0,58	disease	0,6	2	neutral	0,54	deleterious	0,5	neutral	-6	neutral	0,41	medium_impact	-0,61	medium_impact	0,15	medium_impact	0,13	0,65	0,8	19,24	7,09	N	0,34	N	0,35	polymorphism	0,83	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13462	13462	G	T	MI.21665	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1126	376	G	C	Ggc/Tgc	-6,02	0	0	probably_damaging	0,99	neutral	0,18	neutral	4,55	deleterious	-3,94	deleterious	-8,11	medium_impact	3,02	damaging	0,53	damaging	0,21	deleterious	4,13	23,8	0,1	0,4	disease	0,73	disease	0,83	disease	0,67	disease	0,71	4	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,81	low_impact	-2,64	medium_impact	-0,13	medium_impact	1,56	0,57	0,8	19,24	7,09	N	0,28	N	0,88	polymorphism	0,54	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13463	13463	G	C	MI.21666	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1127	376	G	A	gGc/gCc	4,06	1	0	benign	0,22	neutral	0,51	neutral	4,67	neutral	-0,35	deleterious	-5,4	neutral_impact	0,78	damaging	0,49	neutral	0,61	deleterious	2,94	22	0,44	0,55	neutral	0,49	neutral	0,43	disease	0,56	neutral	0,41	2	neutral	0,39	deleterious	0,65	neutral	-6	deleterious	0,64	medium_impact	-0,22	medium_impact	0,24	medium_impact	-0,49	0,71	0,85	19,24	7,09	N	0,5	N	0,75	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13463	13463	G	A	MI.21667	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1127	376	G	D	gGc/gAc	4,06	1	0	probably_damaging	0,96	neutral	0,2	neutral	4,52	deleterious	-6,47	deleterious	-6,3	high_impact	4,61	neutral	0,62	damaging	0,25	deleterious	3,82	23,4	0,08	0,35	disease	0,93	disease	0,83	disease	0,77	disease	0,85	7	neutral	0,97	neutral	0,12	deleterious	2	deleterious	0,82	low_impact	-2,06	medium_impact	-0,1	high_impact	3,01	0,34	0,8	19,24	7,09	P	0,58	P	0,85	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13463	13463	G	T	MI.21668	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1127	376	G	V	gGc/gTc	4,06	1	0	probably_damaging	0,96	neutral	0,5	neutral	4,66	neutral	-2,94	deleterious	-8,11	high_impact	4,06	damaging	0,49	damaging	0,27	deleterious	3,79	23,4	0,1	0,4	disease	0,72	disease	0,79	disease	0,67	disease	0,69	4	neutral	0,95	neutral	0,27	deleterious	2	deleterious	0,8	low_impact	-2,06	medium_impact	0,23	high_impact	2,51	0,5	0,8	19,24	7,09	N	0,48	N	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13465	13465	A	C	MI.21669	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1129	377	S	R	Agc/Cgc	-5,56	0	0	possibly_damaging	0,83	neutral	0,35	neutral	4,53	deleterious	-4,08	deleterious	-4,19	high_impact	4,4	neutral	0,62	neutral	0,4	deleterious	3,58	23,2	0,17	0,45	disease	0,88	disease	0,84	disease	0,74	disease	0,81	6	neutral	0,85	neutral	0,26	deleterious	1	deleterious	0,64	low_impact	-1,4	medium_impact	0,08	high_impact	2,82	0,8	0,85	12,6	12,68	N	0,49	N	0,9	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6043	6043	T	A	MI.2167	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	140	47	L	H	cTt/cAt	-0,11	0	0	probably_damaging	0,94	deleterious	0,01	neutral	2,57	deleterious	-4,53	deleterious	-3,38	high_impact	3,58	damaging	0,59	damaging	0,04	deleterious	3,97	23,6	0,22	0,55	disease	0,84	disease	0,85	neutral	0,28	disease	0,74	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,83	low_impact	-1,88	medium_impact	-0,92	high_impact	2,21	0,4	0,9	2,92	7,3	N	0,26	N	0,83	polymorphism	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13465	13465	A	T	MI.21670	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1129	377	S	C	Agc/Tgc	-5,56	0	0	probably_damaging	0,98	neutral	0,18	neutral	4,59	neutral	-1,97	deleterious	-4,02	medium_impact	2,24	neutral	0,75	neutral	0,73	deleterious	3,44	23	0,21	0,45	disease	0,71	disease	0,74	disease	0,55	disease	0,59	2	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,73	low_impact	-2,35	medium_impact	-0,13	medium_impact	0,84	0,73	0,85	12,6	12,68	N	0,3	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13465	13465	A	G	MI.21671	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1129	377	S	G	Agc/Ggc	-5,56	0	0	possibly_damaging	0,52	neutral	0,34	neutral	4,55	neutral	-0,81	deleterious	-3,39	low_impact	1,79	neutral	0,69	neutral	0,62	deleterious	2	16,19	0,43	0,55	disease	0,59	disease	0,6	disease	0,6	disease	0,64	3	neutral	0,64	neutral	0,41	neutral	-3	neutral	0,36	medium_impact	-0,78	medium_impact	0,07	medium_impact	0,43	0,59	0,8	12,6	12,68	N	0,29	N	0,5	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13466	13466	G	C	MI.21672	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1130	377	S	T	aGc/aCc	3,61	0,57	0	possibly_damaging	0,64	neutral	0,39	neutral	4,64	neutral	-0,35	neutral	-2,38	low_impact	1,58	neutral	0,75	neutral	0,84	neutral	1,77	14,79	0,4	0,5	neutral	0,38	neutral	0,4	disease	0,54	neutral	0,43	1	neutral	0,67	neutral	0,38	neutral	-3	neutral	0,39	medium_impact	-0,98	medium_impact	0,13	medium_impact	0,24	0,8	0,85	12,6	12,68	N	0,37	N	0,63	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13466	13466	G	A	MI.21673	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1130	377	S	N	aGc/aAc	3,61	0,57	0	benign	0,05	neutral	0,31	neutral	4,56	deleterious	-3,04	neutral	-2,34	low_impact	0,9	neutral	0,75	neutral	0,85	deleterious	0,57	7,93	0,61	0,65	disease	0,69	neutral	0,4	neutral	0,45	disease	0,61	2	neutral	0,66	deleterious	0,63	neutral	-6	neutral	0,21	medium_impact	0,47	medium_impact	0,04	medium_impact	-0,38	0,56	0,8	12,6	12,68	N	0,43	N	0,16	polymorphism	1	0,06	rs3902404	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13466	13466	G	T	MI.21674	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1130	377	S	I	aGc/aTc	3,61	0,57	0	probably_damaging	0,95	neutral	0,4	neutral	4,72	neutral	-0,92	deleterious	-4,97	medium_impact	2,96	neutral	0,63	neutral	0,48	deleterious	4,06	23,7	0,31	0,45	disease	0,55	disease	0,84	disease	0,63	disease	0,71	4	neutral	0,95	neutral	0,23	deleterious	1	deleterious	0,7	low_impact	-1,96	medium_impact	0,14	medium_impact	1,5	0,86	0,9	12,6	12,68	N	0,3	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13468	13468	C	G	MI.21675	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1132	378	L	V	Cta/Gta	-0,52	0	0	probably_damaging	0,92	neutral	0,56	neutral	4,23	deleterious	-3,17	deleterious	-2,65	medium_impact	2,85	neutral	0,69	neutral	0,44	deleterious	3,48	23,1	0,46	0,55	disease	0,72	neutral	0,48	disease	0,67	disease	0,63	3	neutral	0,91	neutral	0,32	deleterious	1	deleterious	0,75	low_impact	-1,75	medium_impact	0,29	medium_impact	1,4	0,75	0,85	3,98	7,99	N	0,24	N	0,81	polymorphism	1	0,11	rs28654395	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13468	13468	C	A	MI.21676	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1132	378	L	M	Cta/Ata	-0,52	0	0	probably_damaging	0,99	neutral	0,32	neutral	4,21	deleterious	-3,15	neutral	-1,72	low_impact	1,8	neutral	0,74	neutral	0,67	deleterious	3,71	23,3	0,34	0,5	disease	0,69	neutral	0,43	neutral	0,46	disease	0,55	1	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,72	low_impact	-2,64	medium_impact	0,05	medium_impact	0,44	0,74	0,85	3,98	7,99	N	0,36	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13469	13469	T	G	MI.21677	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1133	378	L	R	cTa/cGa	-0,98	0	0	probably_damaging	0,99	neutral	0,35	neutral	4,15	deleterious	-6,47	deleterious	-5,32	high_impact	4,82	neutral	0,62	neutral	0,34	deleterious	4,23	23,9	0,21	0,45	disease	0,91	disease	0,82	disease	0,77	disease	0,84	7	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-2,64	medium_impact	0,08	high_impact	3,2	0,52	0,8	3,98	7,99	P	0,71	P	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13469	13469	T	A	MI.21678	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1133	378	L	Q	cTa/cAa	-0,98	0	0	probably_damaging	1	neutral	0,28	neutral	4,14	deleterious	-6,65	deleterious	-5,31	high_impact	4,82	neutral	0,64	neutral	0,39	deleterious	4,13	23,8	0,21	0,45	disease	0,95	disease	0,75	disease	0,67	disease	0,82	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,01	high_impact	3,2	0,7	0,85	3,98	7,99	P	0,64	P	0,98	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13469	13469	T	C	MI.21679	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1133	378	L	P	cTa/cCa	-0,98	0	0	probably_damaging	1	neutral	0,19	neutral	4,14	deleterious	-6,9	deleterious	-6,22	high_impact	4,82	neutral	0,62	neutral	0,36	deleterious	3,96	23,6	0,22	0,45	disease	0,96	disease	0,74	disease	0,77	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,12	high_impact	3,2	0,59	0,8	3,98	7,99	P	0,63	P	0,99	polymorphism	0,94	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6043	6043	T	G	MI.2168	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	140	47	L	R	cTt/cGt	-0,11	0	0	possibly_damaging	0,88	deleterious	0	neutral	2,58	deleterious	-4,52	deleterious	-3,15	medium_impact	3,23	damaging	0,57	damaging	0,04	deleterious	4,07	23,7	0,3	0,55	disease	0,79	disease	0,9	neutral	0,49	disease	0,76	5	deleterious	1	neutral	0,06	deleterious	4	deleterious	0,83	low_impact	-1,57	low_impact	-1,48	medium_impact	1,88	0,51	0,9	2,92	7,3	N	0,24	N	0,9	polymorphism	0,97	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13471	13471	G	T	MI.21680	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1135	379	A	S	Gca/Tca	-5,33	0	0	probably_damaging	1	neutral	0,41	neutral	4,88	neutral	-0,69	deleterious	-2,5	low_impact	1,12	damaging	0,59	neutral	0,65	deleterious	3,75	23,3	0,47	0,55	neutral	0,43	disease	0,58	disease	0,56	neutral	0,45	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	0,15	medium_impact	-0,18	0,77	0,85	24,05	7,1	N	0,31	N	0,98	polymorphism	0,84	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13471	13471	G	C	MI.21681	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1135	379	A	P	Gca/Cca	-5,33	0	0	probably_damaging	1	neutral	0,19	neutral	4,45	deleterious	-6,23	deleterious	-4,34	high_impact	4,44	damaging	0,57	neutral	0,37	deleterious	3,87	23,5	0,17	0,45	disease	0,95	disease	0,84	disease	0,78	disease	0,87	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,12	high_impact	2,85	0,67	0,85	24,05	7,1	N	0,5	N	0,96	disease_causing	0,61	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13471	13471	G	A	MI.21682	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1135	379	A	T	Gca/Aca	-5,33	0	0	probably_damaging	1	neutral	0,39	neutral	4,51	deleterious	-3,91	deleterious	-3,26	medium_impact	3,06	damaging	0,52	neutral	0,51	deleterious	4,28	24	0,35	0,5	disease	0,8	disease	0,7	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,13	medium_impact	1,59	0,73	0,85	24,05	7,1	N	0,32	N	0,94	polymorphism	0,69	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13472	13472	C	A	MI.21683	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1136	379	A	E	gCa/gAa	9,11	1	0	probably_damaging	1	neutral	0,2	neutral	4,49	deleterious	-4,71	deleterious	-4,33	high_impact	4,79	damaging	0,58	neutral	0,4	deleterious	4,64	24,5	0,14	0,4	disease	0,93	disease	0,84	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,1	high_impact	3,17	0,64	0,8	24,05	7,1	P	0,75	P	0,99	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13472	13472	C	G	MI.21684	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1136	379	A	G	gCa/gGa	9,11	1	0	probably_damaging	1	neutral	0,4	neutral	4,49	deleterious	-3,47	deleterious	-3,5	medium_impact	2,97	damaging	0,6	neutral	0,52	deleterious	3,96	23,6	0,33	0,5	disease	0,81	disease	0,69	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,14	medium_impact	1,51	0,75	0,85	24,05	7,1	P	0,53	P	0,82	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13472	13472	C	T	MI.21685	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1136	379	A	V	gCa/gTa	9,11	1	0	probably_damaging	1	neutral	0,47	neutral	4,5	deleterious	-4,64	deleterious	-3,46	high_impact	4,09	damaging	0,54	neutral	0,4	deleterious	4,48	24,2	0,39	0,5	disease	0,76	disease	0,77	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,2	high_impact	2,53	0,68	0,85	24,05	7,1	P	0,61	P	0,76	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13474	13474	T	A	MI.21686	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1138	380	L	M	Tta/Ata	-5,1	0	0	probably_damaging	1	neutral	0,22	neutral	4,29	neutral	-1,99	neutral	-1,8	medium_impact	2,65	damaging	0,37	damaging	0,06	deleterious	3,67	23,3	0,42	0,55	disease	0,8	disease	0,59	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,07	medium_impact	1,22	0,83	0,9	30,35	7,16	N	0,48	N	0,89	polymorphism	0,88	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13474	13474	T	G	MI.21687	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1138	380	L	V	Tta/Gta	-5,1	0	0	probably_damaging	1	neutral	0,5	neutral	4,32	deleterious	-3,33	deleterious	-2,7	high_impact	5,07	damaging	0,32	damaging	0,05	deleterious	3,48	23,1	0,42	0,55	disease	0,81	disease	0,59	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,23	high_impact	3,43	0,64	0,8	30,35	7,16	P	0,61	P	0,81	polymorphism	0,86	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13475	13475	T	C	MI.21688	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1139	380	L	S	tTa/tCa	-1,21	0	0	probably_damaging	1	neutral	0,41	neutral	4,31	neutral	-2,67	deleterious	-5,41	high_impact	4,09	damaging	0,35	damaging	0,05	deleterious	3,85	23,4	0,26	0,45	disease	0,7	disease	0,75	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,15	high_impact	2,53	0,6	0,8	30,35	7,16	N	0,47	N	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13475	13475	T	G	MI.21689	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1139	380	L	W	tTa/tGa	-1,21	0	0	probably_damaging	1	neutral	0,18	neutral	4,25	deleterious	-7,2	deleterious	-5,41	high_impact	5,07	damaging	0,34	damaging	0,03	deleterious	3,83	23,4	0,15	0,4	disease	0,97	disease	0,7	disease	0,7	disease	0,84	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,13	high_impact	3,43	0,58	0,8	30,35	7,16	P	0,55	P	0,98	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6045	6045	C	G	MI.2169	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	142	48	L	V	Cta/Gta	-6,81	0	0,02	benign	0,06	deleterious	0	neutral	2,47	neutral	-1,7	neutral	-0,51	medium_impact	2,29	neutral	0,63	neutral	0,46	neutral	1,42	12,91	0,46	0,55	neutral	0,3	disease	0,59	neutral	0,44	neutral	0,48	0	deleterious	1	deleterious	0,47	deleterious	1	neutral	0,2	medium_impact	0,37	low_impact	-1,48	medium_impact	1,02	0,47	0,9	11,5	34,61	N	0,44	N	0,33	polymorphism	1	0,01	rs879061193	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13476	13476	A	C	MI.21690	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1140	380	L	F	ttA/ttC	7,27	0,95	0	probably_damaging	1	neutral	0,72	neutral	4,33	deleterious	-3,97	deleterious	-3,6	high_impact	4,37	damaging	0,32	damaging	0,03	deleterious	3,54	23,1	0,42	0,55	disease	0,82	disease	0,7	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,46	high_impact	2,79	0,73	0,85	30,35	7,16	P	0,64	P	0,99	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13476	13476	A	T	MI.21691	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1140	380	L	F	ttA/ttT	7,27	0,95	0	probably_damaging	1	neutral	0,72	neutral	4,33	deleterious	-3,97	deleterious	-3,6	high_impact	4,37	damaging	0,32	damaging	0,03	deleterious	3,62	23,2	0,42	0,55	disease	0,82	disease	0,7	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,46	high_impact	2,79	0,73	0,85	30,35	7,16	P	0,66	P	0,99	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13477	13477	G	C	MI.21692	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1141	381	A	P	Gca/Cca	-1,89	0	0,01	possibly_damaging	0,81	neutral	0,26	neutral	4,51	deleterious	-6,03	neutral	-1,09	high_impact	3,52	neutral	0,63	neutral	0,37	deleterious	3,67	23,2	0,21	0,45	disease	0,92	disease	0,86	disease	0,55	disease	0,84	7	neutral	0,86	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-1,34	medium_impact	-0,02	high_impact	2,01	0,8	0,85	18,57	13,59	N	0,36	N	0,76	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13477	13477	G	A	MI.21693	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1141	381	A	T	Gca/Aca	-1,89	0	0,01	benign	0,01	neutral	0,56	neutral	4,59	neutral	-2,57	neutral	3,87	neutral_impact	0,78	neutral	0,83	neutral	0,93	neutral	-0,37	0,45	0,66	0,7	disease	0,54	neutral	0,06	neutral	0,2	neutral	0,32	4	neutral	0,42	deleterious	0,78	neutral	-6	neutral	0,14	medium_impact	1,15	medium_impact	0,29	medium_impact	-0,49	0,73	0,85	18,57	13,59	N	0,36	N	0,04	polymorphism	1	0,01	rs200283691	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13477	13477	G	T	MI.21694	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1141	381	A	S	Gca/Tca	-1,89	0	0,01	benign	0,36	neutral	0,52	neutral	4,65	neutral	-2,17	neutral	0,69	neutral_impact	0,52	neutral	0,77	neutral	0,77	deleterious	2,04	16,44	0,6	0,65	disease	0,54	neutral	0,47	neutral	0,43	disease	0,51	0	neutral	0,4	deleterious	0,58	neutral	-6	neutral	0,37	medium_impact	-0,51	medium_impact	0,25	medium_impact	-0,73	0,87	0,9	18,57	13,59	N	0,32	N	0,53	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13478	13478	C	G	MI.21695	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1142	381	A	G	gCa/gGa	2,46	0,01	0	possibly_damaging	0,44	neutral	0,48	neutral	4,61	deleterious	-3,78	neutral	-1,89	low_impact	1,82	neutral	0,75	neutral	0,62	deleterious	2,32	18,29	0,4	0,5	disease	0,66	disease	0,54	disease	0,54	disease	0,64	3	neutral	0,48	deleterious	0,52	neutral	-3	deleterious	0,46	medium_impact	-0,65	medium_impact	0,21	medium_impact	0,46	0,79	0,85	18,57	13,59	N	0,33	N	0,55	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13478	13478	C	T	MI.21696	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1142	381	A	V	gCa/gTa	2,46	0,01	0	benign	0,36	neutral	0,59	neutral	4,62	neutral	-2,04	neutral	-0,13	low_impact	0,98	neutral	0,83	neutral	0,78	deleterious	2,65	20,5	0,58	0,65	disease	0,58	disease	0,59	neutral	0,37	disease	0,5	0	neutral	0,34	deleterious	0,62	neutral	-6	neutral	0,32	medium_impact	-0,51	medium_impact	0,32	medium_impact	-0,31	0,75	0,85	18,57	13,59	N	0,29	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13478	13478	C	A	MI.21697	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1142	381	A	E	gCa/gAa	2,46	0,01	0	possibly_damaging	0,56	neutral	0,26	neutral	4,51	deleterious	-6,03	neutral	-1,08	high_impact	3,52	neutral	0,72	neutral	0,59	deleterious	2,98	22,2	0,2	0,45	disease	0,91	disease	0,8	disease	0,67	disease	0,83	7	neutral	0,74	neutral	0,35	deleterious	1	deleterious	0,64	medium_impact	-0,85	medium_impact	-0,02	high_impact	2,01	0,71	0,85	18,57	13,59	N	0,37	N	0,78	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13480	13480	G	C	MI.21698	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1144	382	G	R	Gga/Cga	-0,29	0	0	probably_damaging	1	neutral	0,35	neutral	3,6	deleterious	-9,94	deleterious	-7,21	high_impact	4,84	damaging	0,36	damaging	0,03	deleterious	4,02	23,6	0,14	0,4	disease	0,99	disease	0,92	disease	0,83	disease	0,89	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	0,08	high_impact	3,22	0,71	0,85	27,36	7,2	P	0,52	P	1	disease_causing	0,77	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13480	13480	G	T	MI.21699	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1144	382	G	W	Gga/Tga	-0,29	0	0	probably_damaging	1	neutral	0,18	neutral	3,58	deleterious	-12,72	deleterious	-7,21	high_impact	5,18	damaging	0,34	damaging	0,02	deleterious	4,48	24,2	0,18	0,45	disease	1	disease	0,9	disease	0,78	disease	0,88	8	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,13	high_impact	3,53	0,34	0,8	27,36	7,2	P	0,47	N	1	disease_causing	0,85	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8627	8627	C	T	MI.217	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	101	34	S	F	tCc/tTc	0,59	0	0	probably_damaging	1	neutral	0,7	neutral	4,26	deleterious	-3,23	deleterious	-3,97	low_impact	0,94	neutral	0,82	damaging	0,15	deleterious	4,11	23,7	0,36	0,65	disease	0,82	disease	0,7	disease	0,61	disease	0,68	4	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	0,5	medium_impact	-0,29	0,39	0,9	9,73	14,65	N	0,19	N	0,91	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6045	6045	C	A	MI.2170	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	142	48	L	M	Cta/Ata	-6,81	0	0,02	benign	0,03	deleterious	0,02	neutral	2,36	deleterious	-3,06	neutral	-0,79	low_impact	1,54	neutral	0,69	neutral	0,72	deleterious	2,42	18,93	0,35	0,55	disease	0,55	neutral	0,43	neutral	0,23	disease	0,61	2	neutral	0,98	deleterious	0,5	neutral	-2	neutral	0,21	medium_impact	0,66	medium_impact	-0,75	medium_impact	0,32	0,71	0,9	11,5	34,61	N	0,46	N	0,38	polymorphism	1	0,02	rs879061193	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13481	13481	G	T	MI.21700	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1145	382	G	V	gGa/gTa	9,11	1	0	probably_damaging	1	neutral	0,51	neutral	3,61	deleterious	-8,79	deleterious	-8,11	high_impact	5,18	damaging	0,33	damaging	0,03	deleterious	3,79	23,4	0,16	0,45	disease	0,93	disease	0,9	disease	0,77	disease	0,84	7	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,24	high_impact	3,53	0,57	0,8	27,36	7,2	P	0,63	P	0,98	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13481	13481	G	C	MI.21701	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1145	382	G	A	gGa/gCa	9,11	1	0	probably_damaging	1	neutral	0,52	neutral	3,82	deleterious	-4,42	deleterious	-5,41	medium_impact	3,18	damaging	0,4	damaging	0,06	deleterious	3,16	22,6	0,24	0,45	disease	0,59	disease	0,7	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,25	medium_impact	1,7	0,5	0,8	27,36	7,2	P	0,61	P	0,79	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13481	13481	G	A	MI.21702	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1145	382	G	E	gGa/gAa	9,11	1	0	probably_damaging	1	neutral	0,28	neutral	3,6	deleterious	-10,01	deleterious	-7,21	high_impact	5,18	damaging	0,27	damaging	0,02	deleterious	3,94	23,5	0,17	0,45	disease	0,99	disease	0,88	disease	0,83	disease	0,89	8	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,01	high_impact	3,53	0,71	0,85	27,36	7,2	P	0,73	P	1	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13483	13483	A	C	MI.21703	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1147	383	M	L	Ata/Cta	-4,42	0	0	benign	0,08	neutral	0,65	neutral	4,93	neutral	2,6	neutral	-1,73	neutral_impact	-0,16	neutral	0,75	neutral	0,64	neutral	1,48	13,19	0,43	0,55	neutral	0,38	disease	0,74	disease	0,65	disease	0,58	2	neutral	0,26	deleterious	0,79	neutral	-6	neutral	0,22	medium_impact	0,26	medium_impact	0,38	low_impact	-1,35	0,63	0,8	8,96	10,68	N	0,29	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13483	13483	A	G	MI.21704	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1147	383	M	V	Ata/Gta	-4,42	0	0	benign	0,02	neutral	0,5	neutral	4,7	neutral	1,27	neutral	-2,02	neutral_impact	0,4	neutral	0,89	neutral	0,86	neutral	-0,14	1,44	0,5	0,6	neutral	0,35	disease	0,71	disease	0,58	disease	0,54	1	neutral	0,48	deleterious	0,74	neutral	-6	neutral	0,21	medium_impact	0,86	medium_impact	0,23	medium_impact	-0,84	0,71	0,85	8,96	10,68	N	0,27	N	0,84	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13483	13483	A	T	MI.21705	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1147	383	M	L	Ata/Tta	-4,42	0	0	benign	0,08	neutral	0,65	neutral	4,93	neutral	2,6	neutral	-1,73	neutral_impact	-0,16	neutral	0,75	neutral	0,64	neutral	1,58	13,75	0,43	0,55	neutral	0,38	disease	0,74	disease	0,65	disease	0,58	2	neutral	0,26	deleterious	0,79	neutral	-6	neutral	0,22	medium_impact	0,26	medium_impact	0,38	low_impact	-1,35	0,63	0,8	8,96	10,68	N	0,29	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13484	13484	T	C	MI.21706	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1148	383	M	T	aTa/aCa	4,52	0,24	0	benign	0,02	neutral	0,4	neutral	4,67	neutral	-0,81	deleterious	-2,61	neutral_impact	-0,12	neutral	0,77	neutral	0,93	neutral	-1,39	0	0,53	0,6	disease	0,52	neutral	0,16	neutral	0,34	neutral	0,21	6	neutral	0,59	deleterious	0,69	neutral	-6	neutral	0,35	medium_impact	0,86	medium_impact	0,14	low_impact	-1,31	0,54	0,8	8,96	10,68	N	0,38	N	0,61	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13484	13484	T	A	MI.21707	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1148	383	M	K	aTa/aAa	4,52	0,24	0	possibly_damaging	0,46	neutral	0,29	neutral	4,6	neutral	-2,99	deleterious	-3,99	medium_impact	3,29	neutral	0,7	neutral	0,41	deleterious	2,59	20,2	0,2	0,45	disease	0,83	disease	0,88	disease	0,73	disease	0,83	7	neutral	0,67	neutral	0,42	NA	0	deleterious	0,67	medium_impact	-0,68	medium_impact	0,02	medium_impact	1,8	0,44	0,8	8,96	10,68	N	0,38	N	0,96	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13485	13485	A	C	MI.21708	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1149	383	M	I	atA/atC	0,17	0,02	0	benign	0,02	neutral	0,39	neutral	4,91	neutral	2,37	neutral	-2,15	neutral_impact	-0,07	neutral	0,84	neutral	0,96	deleterious	0,39	6,57	0,46	0,55	neutral	0,36	disease	0,7	neutral	0,45	disease	0,53	1	neutral	0,59	deleterious	0,69	neutral	-6	neutral	0,2	medium_impact	0,86	medium_impact	0,13	low_impact	-1,27	0,71	0,85	8,96	10,68	N	0,31	N	0,84	polymorphism	1	0,02	rs28359176	Likely benign	not_provided	RCV000224130.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	13485	13485	A	T	MI.21709	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1149	383	M	I	atA/atT	0,17	0,02	0	benign	0,02	neutral	0,39	neutral	4,91	neutral	2,37	neutral	-2,15	neutral_impact	-0,07	neutral	0,84	neutral	0,96	deleterious	0,47	7,18	0,46	0,55	neutral	0,36	disease	0,7	neutral	0,45	disease	0,53	1	neutral	0,59	deleterious	0,69	neutral	-6	neutral	0,2	medium_impact	0,86	medium_impact	0,13	low_impact	-1,27	0,71	0,85	8,96	10,68	N	0,31	N	0,84	polymorphism	1	0,02	rs28359176	Likely benign	not_provided	RCV000224130.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	6046	6046	T	G	MI.2171	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	143	48	L	R	cTa/cGa	-2,88	0	0	possibly_damaging	0,67	deleterious	0	neutral	2,31	deleterious	-4,82	deleterious	-3,31	high_impact	3,53	neutral	0,62	neutral	0,32	deleterious	3,97	23,6	0,28	0,55	neutral	0,49	disease	0,89	disease	0,7	disease	0,81	6	deleterious	1	neutral	0,17	deleterious	5	deleterious	0,68	low_impact	-1,05	low_impact	-1,48	high_impact	2,16	0,67	0,9	11,5	34,61	N	0,3	N	0,93	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13486	13486	C	G	MI.21710	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1150	384	P	A	Cct/Gct	-6,94	0	0	probably_damaging	1	neutral	0,56	neutral	3,56	deleterious	-6,53	deleterious	-7,18	high_impact	4,04	damaging	0,3	neutral	0,54	deleterious	3,13	22,6	0,19	0,45	disease	0,95	disease	0,72	disease	0,77	disease	0,84	7	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,29	high_impact	2,49	0,63	0,8	28,69	7,27	P	0,61	P	0,73	polymorphism	0,68	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13486	13486	C	T	MI.21711	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1150	384	P	S	Cct/Tct	-6,94	0	0	probably_damaging	1	neutral	0,45	neutral	3,54	deleterious	-7,27	deleterious	-7,18	high_impact	4,63	damaging	0,31	neutral	0,58	deleterious	3,96	23,6	0,26	0,45	disease	0,95	disease	0,85	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,18	high_impact	3,03	0,37	0,8	28,69	7,27	P	0,69	P	0,78	polymorphism	0,56	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13486	13486	C	A	MI.21712	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1150	384	P	T	Cct/Act	-6,94	0	0	probably_damaging	1	neutral	0,47	neutral	3,54	deleterious	-7,12	deleterious	-7,18	high_impact	4,63	damaging	0,31	neutral	0,42	deleterious	3,76	23,3	0,22	0,45	disease	0,96	disease	0,84	disease	0,77	disease	0,86	7	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,2	high_impact	3,03	0,65	0,8	28,69	7,27	P	0,65	P	0,91	polymorphism	0,57	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13487	13487	C	T	MI.21713	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1151	384	P	L	cCt/cTt	5,44	1	0	probably_damaging	1	neutral	0,85	neutral	3,62	deleterious	-6,14	deleterious	-8,98	high_impact	3,83	damaging	0,19	neutral	0,44	deleterious	4,35	24,1	0,25	0,45	disease	0,82	disease	0,9	disease	0,74	disease	0,8	6	deleterious	1	neutral	0,43	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,65	high_impact	2,3	0,79	0,85	28,69	7,27	P	0,87	P	0,97	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13487	13487	C	A	MI.21714	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1151	384	P	H	cCt/cAt	5,44	1	0	probably_damaging	1	neutral	0,53	neutral	3,52	deleterious	-8,86	deleterious	-8,08	high_impact	5,18	damaging	0,31	neutral	0,37	deleterious	4,11	23,7	0,21	0,45	disease	0,97	disease	0,88	disease	0,83	disease	0,85	7	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,26	high_impact	3,53	0,58	0,8	28,69	7,27	P	0,73	P	0,72	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13487	13487	C	G	MI.21715	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1151	384	P	R	cCt/cGt	5,44	1	0	probably_damaging	1	neutral	0,36	neutral	3,53	deleterious	-8,31	deleterious	-8,08	high_impact	5,18	damaging	0,34	neutral	0,41	deleterious	3,61	23,2	0,18	0,45	disease	0,98	disease	0,92	disease	0,85	disease	0,87	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,1	high_impact	3,53	0,62	0,8	28,69	7,27	P	0,73	P	0,64	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13489	13489	T	C	MI.21716	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1153	385	F	L	Ttc/Ctc	-12,21	0	0	probably_damaging	1	neutral	0,73	neutral	4,69	neutral	0,53	deleterious	-5,24	medium_impact	2,85	neutral	0,62	neutral	0,59	deleterious	4,14	23,8	0,5	0,6	neutral	0,5	disease	0,8	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,47	medium_impact	1,4	0,84	0,9	18,24	7,04	N	0,28	N	0,92	polymorphism	0,85	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13489	13489	T	A	MI.21717	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1153	385	F	I	Ttc/Atc	-12,21	0	0	probably_damaging	1	neutral	0,39	neutral	4,63	neutral	-1,33	deleterious	-5,26	high_impact	3,79	neutral	0,64	neutral	0,62	deleterious	4,47	24,2	0,26	0,45	disease	0,59	disease	0,82	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,13	high_impact	2,26	0,74	0,85	18,24	7,04	N	0,38	N	0,95	polymorphism	0,86	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13489	13489	T	G	MI.21718	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1153	385	F	V	Ttc/Gtc	-12,21	0	0	probably_damaging	1	neutral	0,51	neutral	4,63	neutral	-1,24	deleterious	-6,12	high_impact	3,86	neutral	0,65	neutral	0,53	deleterious	4,21	23,9	0,42	0,55	disease	0,55	disease	0,87	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,24	high_impact	2,32	0,6	0,8	18,24	7,04	N	0,34	N	0,95	polymorphism	0,75	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13490	13490	T	C	MI.21719	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1154	385	F	S	tTc/tCc	7,27	1	0	probably_damaging	1	neutral	0,44	neutral	4,57	neutral	-2,55	deleterious	-7,04	high_impact	4,28	neutral	0,68	neutral	0,59	deleterious	4,27	24	0,33	0,5	disease	0,74	disease	0,86	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,18	high_impact	2,71	0,57	0,8	18,24	7,04	P	0,63	P	0,97	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6046	6046	T	C	MI.2172	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	143	48	L	P	cTa/cCa	-2,88	0	0	possibly_damaging	0,9	deleterious	0	neutral	2,31	deleterious	-4,6	deleterious	-3,61	high_impact	3,88	neutral	0,61	neutral	0,36	deleterious	3,72	23,3	0,21	0,55	disease	0,65	disease	0,9	disease	0,56	disease	0,78	6	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,86	low_impact	-1,65	low_impact	-1,48	high_impact	2,48	0,55	0,9	11,5	34,61	N	0,37	N	0,83	polymorphism	0,88	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13490	13490	T	G	MI.21720	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1154	385	F	C	tTc/tGc	7,27	1	0	probably_damaging	1	neutral	0,17	neutral	4,53	deleterious	-3,97	deleterious	-7,03	high_impact	4,83	neutral	0,65	neutral	0,49	deleterious	4,12	23,8	0,32	0,5	disease	0,88	disease	0,88	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,15	high_impact	3,21	0,38	0,8	18,24	7,04	P	0,71	P	0,99	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13490	13490	T	A	MI.21721	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1154	385	F	Y	tTc/tAc	7,27	1	0	probably_damaging	1	neutral	1	neutral	4,56	neutral	-2,52	neutral	-2,43	medium_impact	2,4	neutral	0,78	neutral	0,88	deleterious	4,23	23,9	0,29	0,45	disease	0,67	disease	0,69	disease	0,66	disease	0,51	0	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,79	low_impact	-3,6	high_impact	1,89	medium_impact	0,99	0,68	0,85	18,24	7,04	N	0,5	N	0,88	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13491	13491	C	G	MI.21722	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1155	385	F	L	ttC/ttG	3,61	1	0	probably_damaging	1	neutral	0,73	neutral	4,69	neutral	0,53	deleterious	-5,24	medium_impact	2,85	neutral	0,62	neutral	0,59	deleterious	4,45	24,2	0,5	0,6	neutral	0,5	disease	0,8	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,47	medium_impact	1,4	0,84	0,9	18,24	7,04	N	0,39	N	0,92	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13491	13491	C	A	MI.21723	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1155	385	F	L	ttC/ttA	3,61	1	0	probably_damaging	1	neutral	0,73	neutral	4,69	neutral	0,53	deleterious	-5,24	medium_impact	2,85	neutral	0,62	neutral	0,59	deleterious	4,78	24,7	0,5	0,6	neutral	0,5	disease	0,8	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,47	medium_impact	1,4	0,84	0,9	18,24	7,04	N	0,4	N	0,92	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13492	13492	C	G	MI.21724	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1156	386	L	V	Ctc/Gtc	-1,21	0	0	benign	0,22	neutral	0,49	neutral	4,36	neutral	-2,78	deleterious	-2,7	high_impact	3,63	damaging	0,48	neutral	0,44	neutral	1,59	13,78	0,48	0,55	disease	0,74	disease	0,69	disease	0,72	disease	0,72	4	neutral	0,41	deleterious	0,64	neutral	-2	neutral	0,28	medium_impact	-0,22	medium_impact	0,22	high_impact	2,11	0,69	0,85	26,53	7,19	N	0,4	N	0,81	disease_causing	0,97	0,1	rs28376363	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13492	13492	C	T	MI.21725	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1156	386	L	F	Ctc/Ttc	-1,21	0	0	probably_damaging	0,98	neutral	0,84	neutral	4,35	neutral	-0,33	deleterious	-3,6	low_impact	1,74	damaging	0,54	neutral	0,46	deleterious	3,96	23,6	0,39	0,5	disease	0,54	disease	0,73	disease	0,7	disease	0,59	2	neutral	0,98	neutral	0,43	neutral	-2	deleterious	0,73	low_impact	-2,35	medium_impact	0,63	medium_impact	0,39	0,68	0,85	26,53	7,19	N	0,26	N	0,99	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13492	13492	C	A	MI.21726	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1156	386	L	I	Ctc/Atc	-1,21	0	0	possibly_damaging	0,68	neutral	0,38	neutral	4,31	deleterious	-3,24	neutral	-1,8	medium_impact	3,45	damaging	0,56	neutral	0,55	deleterious	2,52	19,6	0,34	0,5	disease	0,79	disease	0,71	disease	0,71	disease	0,75	5	neutral	0,71	neutral	0,35	NA	0	deleterious	0,44	low_impact	-1,06	medium_impact	0,12	medium_impact	1,95	0,73	0,85	26,53	7,19	N	0,33	N	0,85	disease_causing	0,94	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13493	13493	T	G	MI.21727	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1157	386	L	R	cTc/cGc	-0,06	0	0	probably_damaging	0,99	neutral	0,35	neutral	4,26	deleterious	-5,56	deleterious	-5,39	high_impact	4,49	damaging	0,58	neutral	0,34	deleterious	4,19	23,8	0,17	0,45	disease	0,92	disease	0,91	disease	0,8	disease	0,87	7	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-2,64	medium_impact	0,08	high_impact	2,9	0,57	0,8	26,53	7,19	N	0,53	P	1	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13493	13493	T	C	MI.21728	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1157	386	L	P	cTc/cCc	-0,06	0	0	probably_damaging	0,99	neutral	0,25	neutral	4,25	deleterious	-5,82	deleterious	-6,29	high_impact	4,49	damaging	0,53	neutral	0,37	deleterious	3,93	23,5	0,19	0,45	disease	0,95	disease	0,83	disease	0,7	disease	0,84	7	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,89	low_impact	-2,64	medium_impact	-0,03	high_impact	2,9	0,63	0,8	26,53	7,19	N	0,4	N	0,99	disease_causing	1	0,32	.	.	.	.	.	oncocytoma	.	.	.	.	.	.	.	.	.
chrM	13493	13493	T	A	MI.21729	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1157	386	L	H	cTc/cAc	-0,06	0	0	probably_damaging	0,99	neutral	0,5	neutral	4,25	deleterious	-6,08	deleterious	-6,29	high_impact	4,84	damaging	0,55	neutral	0,37	deleterious	4,16	23,8	0,2	0,45	disease	0,94	disease	0,83	disease	0,78	disease	0,87	7	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-2,64	medium_impact	0,23	high_impact	3,22	0,66	0,8	26,53	7,19	P	0,68	P	0,97	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6046	6046	T	A	MI.2173	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	143	48	L	Q	cTa/cAa	-2,88	0	0	possibly_damaging	0,67	deleterious	0	neutral	2,3	deleterious	-5	deleterious	-3,29	high_impact	3,53	neutral	0,67	neutral	0,43	deleterious	3,85	23,4	0,26	0,55	neutral	0,48	disease	0,77	disease	0,57	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	5	deleterious	0,63	low_impact	-1,05	low_impact	-1,48	high_impact	2,16	0,62	0,9	11,5	34,61	N	0,37	N	0,8	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13495	13495	A	T	MI.21730	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1159	387	T	S	Aca/Tca	-3,5	0	0	benign	0,2	neutral	0,43	neutral	4,68	neutral	1,95	deleterious	-3,44	neutral_impact	-1,53	neutral	0,73	neutral	0,6	deleterious	0,19	4,53	0,53	0,6	neutral	0,33	neutral	0,35	neutral	0,39	neutral	0,45	1	neutral	0,48	deleterious	0,62	neutral	-6	neutral	0,2	medium_impact	-0,17	medium_impact	0,17	low_impact	-2,6	0,84	0,9	14,59	15,42	N	0,33	N	0,12	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13495	13495	A	G	MI.21731	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1159	387	T	A	Aca/Gca	-3,5	0	0	benign	0,13	neutral	0,51	neutral	4,7	neutral	1,65	deleterious	-4,21	neutral_impact	-1,3	neutral	0,72	neutral	0,82	neutral	-0,87	0,03	0,58	0,65	neutral	0,35	neutral	0,09	neutral	0,34	neutral	0,22	6	neutral	0,4	deleterious	0,69	neutral	-6	neutral	0,41	medium_impact	0,04	medium_impact	0,24	low_impact	-2,39	0,49	0,8	14,59	15,42	N	0,39	N	0,45	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13495	13495	A	C	MI.21732	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1159	387	T	P	Aca/Cca	-3,5	0	0	probably_damaging	0,96	neutral	0,21	neutral	4,52	neutral	-1,93	deleterious	-5,24	medium_impact	2,29	neutral	0,65	neutral	0,32	deleterious	3,45	23	0,21	0,45	disease	0,7	disease	0,91	disease	0,64	disease	0,79	6	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,84	low_impact	-2,06	medium_impact	-0,09	medium_impact	0,89	0,65	0,8	14,59	15,42	N	0,26	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13496	13496	C	T	MI.21733	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1160	387	T	M	aCa/aTa	1,77	0,97	0	probably_damaging	0,98	neutral	0,23	neutral	4,57	neutral	-1,77	deleterious	-5,24	medium_impact	2,29	neutral	0,77	neutral	0,48	deleterious	4,07	23,7	0,3	0,45	disease	0,82	disease	0,76	disease	0,67	disease	0,77	5	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,8	low_impact	-2,35	medium_impact	-0,06	medium_impact	0,89	0,75	0,85	14,59	15,42	N	0,32	N	0,88	polymorphism	0,88	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13496	13496	C	A	MI.21734	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1160	387	T	K	aCa/aAa	1,77	0,97	0	possibly_damaging	0,83	neutral	0,29	neutral	4,53	neutral	-2,28	deleterious	-5,24	medium_impact	2,85	neutral	0,71	neutral	0,39	deleterious	4,18	23,8	0,2	0,45	disease	0,66	disease	0,89	disease	0,74	disease	0,82	6	neutral	0,87	neutral	0,23	NA	0	deleterious	0,71	low_impact	-1,4	medium_impact	0,02	medium_impact	1,4	0,73	0,85	14,59	15,42	N	0,42	N	0,85	polymorphism	0,81	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13498	13498	G	T	MI.21735	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1162	388	G	C	Ggt/Tgt	-0,29	0,49	0	probably_damaging	1	neutral	0,19	neutral	4,21	deleterious	-7,14	deleterious	-8,09	high_impact	3,79	damaging	0,31	damaging	0,05	deleterious	4,24	23,9	0,12	0,4	disease	0,88	disease	0,91	disease	0,79	disease	0,82	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,12	high_impact	2,26	0,62	0,8	29,52	7,17	P	0,57	P	0,97	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13498	13498	G	C	MI.21736	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1162	388	G	R	Ggt/Cgt	-0,29	0,49	0	probably_damaging	1	neutral	0,35	neutral	4,24	deleterious	-6,84	deleterious	-7,19	high_impact	4,83	damaging	0,35	damaging	0,03	deleterious	4,07	23,7	0,11	0,4	disease	0,93	disease	0,93	disease	0,86	disease	0,88	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,94	low_impact	-3,6	medium_impact	0,08	high_impact	3,21	0,71	0,85	29,52	7,17	P	0,62	P	1	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13498	13498	G	A	MI.21737	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1162	388	G	S	Ggt/Agt	-0,29	0,49	0	probably_damaging	1	neutral	0,45	neutral	4,31	deleterious	-5,51	deleterious	-5,4	high_impact	3,73	damaging	0,33	damaging	0,05	deleterious	4,25	23,9	0,18	0,45	disease	0,76	disease	0,86	disease	0,78	disease	0,79	6	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,18	high_impact	2,2	0,64	0,8	29,52	7,17	P	0,59	P	1	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13499	13499	G	C	MI.21738	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1163	388	G	A	gGt/gCt	9,11	1	0	probably_damaging	1	neutral	0,55	neutral	4,26	deleterious	-5,3	deleterious	-5,4	medium_impact	3,1	damaging	0,37	damaging	0,08	deleterious	3,19	22,7	0,23	0,45	disease	0,86	disease	0,75	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	0,28	medium_impact	1,63	0,7	0,85	29,52	7,17	P	0,66	P	0,79	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13499	13499	G	T	MI.21739	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1163	388	G	V	gGt/gTt	9,11	1	0	probably_damaging	1	neutral	0,51	neutral	4,23	deleterious	-5,19	deleterious	-8,09	high_impact	5,17	damaging	0,3	damaging	0,03	deleterious	3,86	23,5	0,12	0,4	disease	0,87	disease	0,92	disease	0,81	disease	0,86	7	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,24	high_impact	3,52	0,57	0,8	29,52	7,17	P	0,71	P	0,98	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6048	6048	G	C	MI.2174	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	145	49	G	R	Ggt/Cgt	-3,11	0	0	possibly_damaging	0,83	deleterious	0,01	neutral	2,84	neutral	-0,52	deleterious	-3,92	high_impact	4,19	neutral	0,62	damaging	0,07	deleterious	3,77	23,4	0,31	0,55	disease	0,51	disease	0,93	disease	0,57	disease	0,76	5	deleterious	0,99	neutral	0,09	deleterious	5	deleterious	0,82	low_impact	-1,4	medium_impact	-0,92	high_impact	2,77	0,8	0,9	7,99	32,29	N	0,29	N	0,95	polymorphism	0,79	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13499	13499	G	A	MI.21740	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1163	388	G	D	gGt/gAt	9,11	1	0	probably_damaging	1	neutral	0,22	neutral	4,23	deleterious	-7,44	deleterious	-6,29	high_impact	5,17	damaging	0,29	damaging	0,02	deleterious	3,89	23,5	0,12	0,4	disease	0,94	disease	0,92	disease	0,86	disease	0,86	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,07	high_impact	3,52	0,41	0,8	29,52	7,17	P	0,76	P	0,95	disease_causing	1	0,44	.	.	.	.	.	.	COSM488749	.	.	.	.	.	.	.	.
chrM	13501	13501	T	C	MI.21741	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1165	389	F	L	Ttc/Ctc	-7,4	0	0	possibly_damaging	0,81	neutral	0,66	neutral	3,51	deleterious	-5,55	deleterious	-5,39	high_impact	4,79	damaging	0,37	neutral	0,54	deleterious	4,21	23,9	0,18	0,45	disease	0,8	disease	0,85	disease	0,76	disease	0,8	6	neutral	0,78	neutral	0,43	deleterious	1	deleterious	0,87	low_impact	-1,34	medium_impact	0,39	high_impact	3,17	0,57	0,8	15,75	7,18	P	0,74	P	0,92	disease_causing	0,58	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13501	13501	T	A	MI.21742	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1165	389	F	I	Ttc/Atc	-7,4	0	0	probably_damaging	0,94	neutral	0,4	neutral	3,4	deleterious	-6,24	deleterious	-5,39	high_impact	4,24	damaging	0,45	neutral	0,64	deleterious	4,55	24,3	0,12	0,4	disease	0,96	disease	0,87	disease	0,79	disease	0,84	7	neutral	0,94	neutral	0,23	deleterious	2	deleterious	0,89	low_impact	-1,88	medium_impact	0,14	high_impact	2,67	0,42	0,8	15,75	7,18	N	0,51	P	0,95	disease_causing	0,56	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13501	13501	T	G	MI.21743	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1165	389	F	V	Ttc/Gtc	-7,4	0	0	probably_damaging	0,91	neutral	0,5	neutral	3,4	deleterious	-5,82	deleterious	-6,29	high_impact	5,13	damaging	0,39	neutral	0,53	deleterious	4,24	23,9	0,11	0,4	disease	0,96	disease	0,91	disease	0,8	disease	0,84	7	neutral	0,9	neutral	0,3	deleterious	2	deleterious	0,9	low_impact	-1,7	medium_impact	0,23	high_impact	3,48	0,41	0,8	15,75	7,18	P	0,73	P	0,95	disease_causing	0,73	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13502	13502	T	G	MI.21744	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1166	389	F	C	tTc/tGc	5,67	1	0	probably_damaging	0,99	neutral	0,18	neutral	3,37	deleterious	-8,34	deleterious	-7,19	high_impact	4,79	damaging	0,45	neutral	0,53	deleterious	4,2	23,9	0,1	0,4	disease	0,99	disease	0,89	disease	0,8	disease	0,89	8	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-2,64	medium_impact	-0,13	high_impact	3,17	0,32	0,8	15,75	7,18	P	0,65	P	0,99	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13502	13502	T	A	MI.21745	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1166	389	F	Y	tTc/tAc	5,67	1	0	benign	0,17	neutral	1	neutral	3,47	deleterious	-5,45	deleterious	-2,7	medium_impact	2,31	damaging	0,57	neutral	0,61	deleterious	4,33	24	0,16	0,45	disease	0,87	disease	0,79	disease	0,74	disease	0,69	4	neutral	0,17	deleterious	0,92	neutral	-3	deleterious	0,87	medium_impact	-0,09	high_impact	1,89	medium_impact	0,91	0,48	0,8	15,75	7,18	P	0,51	P	0,88	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13502	13502	T	C	MI.21746	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1166	389	F	S	tTc/tCc	5,67	1	0	probably_damaging	0,96	neutral	0,43	neutral	3,38	deleterious	-7	deleterious	-7,19	high_impact	4,33	damaging	0,49	neutral	0,68	deleterious	4,33	24	0,06	0,35	disease	0,98	disease	0,89	disease	0,77	disease	0,88	8	neutral	0,96	neutral	0,24	deleterious	2	deleterious	0,91	low_impact	-2,06	medium_impact	0,17	high_impact	2,75	0,41	0,8	15,75	7,18	P	0,6	P	0,97	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13503	13503	C	G	MI.21747	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1167	389	F	L	ttC/ttG	3,61	1	0	possibly_damaging	0,81	neutral	0,66	neutral	3,51	deleterious	-5,55	deleterious	-5,39	high_impact	4,79	damaging	0,37	neutral	0,54	deleterious	4,46	24,2	0,18	0,45	disease	0,8	disease	0,85	disease	0,76	disease	0,8	6	neutral	0,78	neutral	0,43	deleterious	1	deleterious	0,87	low_impact	-1,34	medium_impact	0,39	high_impact	3,17	0,57	0,8	15,75	7,18	P	0,78	P	0,92	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13503	13503	C	A	MI.21748	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1167	389	F	L	ttC/ttA	3,61	1	0	possibly_damaging	0,81	neutral	0,66	neutral	3,51	deleterious	-5,55	deleterious	-5,39	high_impact	4,79	damaging	0,37	neutral	0,54	deleterious	4,69	24,6	0,18	0,45	disease	0,8	disease	0,85	disease	0,76	disease	0,8	6	neutral	0,78	neutral	0,43	deleterious	1	deleterious	0,87	low_impact	-1,34	medium_impact	0,39	high_impact	3,17	0,57	0,8	15,75	7,18	P	0,78	P	0,92	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13504	13504	T	G	MI.21749	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1168	390	Y	D	Tac/Gac	-1,89	0	0	probably_damaging	0,96	neutral	0,22	neutral	4,47	deleterious	-4,22	deleterious	-8,99	high_impact	4,62	neutral	0,61	neutral	0,42	deleterious	3,87	23,5	0,19	0,45	disease	0,93	disease	0,92	disease	0,8	disease	0,88	8	neutral	0,97	neutral	0,13	deleterious	2	deleterious	0,85	low_impact	-2,06	medium_impact	-0,07	high_impact	3,02	0,4	0,8	17,74	7,12	P	0,6	P	0,96	disease_causing	0,96	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6048	6048	G	A	MI.2175	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	145	49	G	S	Ggt/Agt	-3,11	0	0	possibly_damaging	0,44	neutral	0,07	neutral	2,87	neutral	-1,57	deleterious	-2,84	medium_impact	2,3	neutral	0,67	damaging	0,08	deleterious	4,02	23,6	0,42	0,55	neutral	0,38	disease	0,86	neutral	0,4	disease	0,53	1	neutral	0,92	neutral	0,32	NA	0	deleterious	0,55	medium_impact	-0,66	medium_impact	-0,43	medium_impact	1,03	0,73	0,9	7,99	32,29	N	0,27	N	0,73	polymorphism	0,89	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13504	13504	T	C	MI.21750	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1168	390	Y	H	Tac/Cac	-1,89	0	0	benign	0,17	neutral	0,53	neutral	4,47	deleterious	-3,37	deleterious	-4,5	high_impact	3,58	neutral	0,72	neutral	0,47	neutral	1,67	14,26	0,42	0,5	disease	0,89	disease	0,82	disease	0,79	disease	0,85	7	neutral	0,37	deleterious	0,68	neutral	-2	neutral	0,36	medium_impact	-0,09	medium_impact	0,26	high_impact	2,07	0,56	0,8	17,74	7,12	N	0,33	N	0,98	disease_causing	0,77	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13504	13504	T	A	MI.21751	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1168	390	Y	N	Tac/Aac	-1,89	0	0	probably_damaging	0,92	neutral	0,3	neutral	4,48	deleterious	-3,69	deleterious	-8,09	high_impact	4,62	neutral	0,62	neutral	0,48	deleterious	3,78	23,4	0,28	0,45	disease	0,87	disease	0,9	disease	0,73	disease	0,83	7	neutral	0,93	neutral	0,19	deleterious	2	deleterious	0,71	low_impact	-1,75	medium_impact	0,03	high_impact	3,02	0,38	0,8	17,74	7,12	P	0,54	P	0,99	disease_causing	0,97	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13505	13505	A	G	MI.21752	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1169	390	Y	C	tAc/tGc	7,27	1	0	probably_damaging	0,98	neutral	0,18	neutral	4,49	deleterious	-3,39	deleterious	-8,09	high_impact	4,07	damaging	0,57	neutral	0,38	deleterious	3,6	23,2	0,28	0,45	disease	0,75	disease	0,91	disease	0,75	disease	0,81	6	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-2,35	medium_impact	-0,13	high_impact	2,52	0,3	0,8	17,74	7,12	P	0,56	P	1	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13505	13505	A	T	MI.21753	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1169	390	Y	F	tAc/tTc	7,27	1	0	possibly_damaging	0,85	neutral	0,74	neutral	4,58	neutral	0,96	deleterious	-3,6	neutral_impact	0,64	neutral	0,67	neutral	0,75	neutral	1,03	10,85	0,4	0,5	neutral	0,36	neutral	0,22	neutral	0,42	neutral	0,39	2	neutral	0,82	neutral	0,45	neutral	-3	deleterious	0,61	low_impact	-1,46	medium_impact	0,48	medium_impact	-0,62	0,6	0,8	17,74	7,12	P	0,53	P	0,8	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13505	13505	A	C	MI.21754	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1169	390	Y	S	tAc/tCc	7,27	1	0	probably_damaging	0,92	neutral	0,43	neutral	4,5	neutral	-2,36	deleterious	-8,09	high_impact	4,62	neutral	0,65	neutral	0,54	deleterious	3,58	23,2	0,27	0,45	disease	0,69	disease	0,87	disease	0,71	disease	0,77	5	neutral	0,92	neutral	0,26	deleterious	2	deleterious	0,74	low_impact	-1,75	medium_impact	0,17	high_impact	3,02	0,4	0,8	17,74	7,12	P	0,66	P	0,97	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13507	13507	T	A	MI.21755	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1171	391	S	T	Tcc/Acc	-1,21	0,01	0	probably_damaging	1	neutral	0,41	neutral	4,41	deleterious	-4,35	deleterious	-2,7	medium_impact	3,25	damaging	0,33	damaging	0,08	deleterious	4,1	23,7	0,18	0,45	disease	0,92	disease	0,76	disease	0,58	disease	0,76	5	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,15	medium_impact	1,77	0,72	0,85	28,69	7,21	N	0,46	N	0,71	disease_causing	0,93	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13507	13507	T	C	MI.21756	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1171	391	S	P	Tcc/Ccc	-1,21	0,01	0	probably_damaging	1	neutral	0,2	neutral	4,41	deleterious	-6,04	deleterious	-4,5	high_impact	4,44	damaging	0,3	damaging	0,06	deleterious	4,15	23,8	0,2	0,45	disease	0,86	disease	0,85	disease	0,78	disease	0,83	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,1	high_impact	2,85	0,61	0,8	28,69	7,21	P	0,61	P	0,98	disease_causing	0,99	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13507	13507	T	G	MI.21757	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1171	391	S	A	Tcc/Gcc	-1,21	0,01	0	probably_damaging	1	neutral	0,54	neutral	4,5	neutral	-2,44	deleterious	-2,7	medium_impact	3,17	damaging	0,38	damaging	0,14	deleterious	3,82	23,4	0,23	0,45	disease	0,6	disease	0,65	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,27	medium_impact	1,69	0,75	0,85	28,69	7,21	N	0,49	N	0,49	disease_causing	0,81	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13508	13508	C	G	MI.21758	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1172	391	S	C	tCc/tGc	5,44	1	0	probably_damaging	1	neutral	0,18	neutral	4,41	deleterious	-7,88	deleterious	-4,5	high_impact	4,58	damaging	0,36	damaging	0,03	deleterious	3,68	23,3	0,19	0,45	disease	0,98	disease	0,84	disease	0,68	disease	0,83	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,13	high_impact	2,98	0,52	0,8	28,69	7,21	P	0,58	P	0,99	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13508	13508	C	A	MI.21759	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1172	391	S	Y	tCc/tAc	5,44	1	0	probably_damaging	1	neutral	1	neutral	4,37	deleterious	-7,98	deleterious	-5,4	high_impact	4,79	damaging	0,34	damaging	0,05	deleterious	4,19	23,8	0,14	0,4	disease	0,99	disease	0,89	disease	0,72	disease	0,84	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,9	low_impact	-3,6	high_impact	1,89	high_impact	3,17	0,65	0,8	28,69	7,21	P	0,59	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6048	6048	G	T	MI.2176	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	145	49	G	C	Ggt/Tgt	-3,11	0	0	probably_damaging	0,95	deleterious	0,02	neutral	2,81	deleterious	-4,86	deleterious	-4,72	high_impact	3,99	neutral	0,61	damaging	0,07	deleterious	4,01	23,6	0,25	0,55	disease	0,77	disease	0,94	neutral	0,45	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,88	low_impact	-1,96	medium_impact	-0,75	high_impact	2,59	0,5	0,9	7,99	32,29	N	0,3	N	0,98	polymorphism	0,66	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13508	13508	C	T	MI.21760	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1172	391	S	F	tCc/tTc	5,44	1	0	probably_damaging	1	neutral	0,88	neutral	4,38	deleterious	-7,61	deleterious	-5,4	high_impact	5,13	damaging	0,37	damaging	0,03	deleterious	4,37	24,1	0,17	0,45	disease	0,99	disease	0,9	disease	0,72	disease	0,85	7	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,71	high_impact	3,48	0,36	0,8	28,69	7,21	P	0,6	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13510	13510	A	G	MI.21761	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1174	392	K	E	Aaa/Gaa	-7,4	0	0	probably_damaging	1	neutral	1	neutral	4,12	neutral	-2,11	deleterious	-3,6	high_impact	5,22	damaging	0,41	damaging	0,18	deleterious	4,1	23,7	0,32	0,5	disease	0,52	disease	0,86	disease	0,73	disease	0,76	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,83	low_impact	-3,6	high_impact	1,89	high_impact	3,57	0,6	0,8	27,69	7,26	P	0,65	P	0,84	disease_causing	0,75	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13510	13510	A	C	MI.21762	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1174	392	K	Q	Aaa/Caa	-7,4	0	0	probably_damaging	1	neutral	0,64	neutral	3,84	deleterious	-5,38	deleterious	-3,6	high_impact	4,67	damaging	0,42	damaging	0,16	deleterious	3,56	23,1	0,3	0,45	disease	0,85	disease	0,82	disease	0,69	disease	0,77	5	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,37	high_impact	3,06	0,55	0,8	27,69	7,26	P	0,54	P	0,82	disease_causing	0,64	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13511	13511	A	T	MI.21763	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1175	392	K	M	aAa/aTa	8,42	1	0	probably_damaging	1	neutral	0,22	neutral	3,8	deleterious	-6,85	deleterious	-5,39	high_impact	4,33	damaging	0,41	damaging	0,18	deleterious	4,08	23,7	0,22	0,45	disease	0,94	disease	0,84	disease	0,69	disease	0,82	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,07	high_impact	2,75	0,38	0,8	27,69	7,26	P	0,72	P	0,4	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	A13511T	Leigh-likesyndrome	-	+	Reported	1
chrM	13511	13511	A	C	MI.21764	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1175	392	K	T	aAa/aCa	8,42	1	0	probably_damaging	1	neutral	0,71	neutral	3,83	deleterious	-5,68	deleterious	-5,39	high_impact	5,22	damaging	0,38	damaging	0,17	deleterious	3,7	23,3	0,24	0,45	disease	0,91	disease	0,86	disease	0,71	disease	0,8	6	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,45	high_impact	3,57	0,31	0,8	27,69	7,26	P	0,78	P	0,75	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13512	13512	A	T	MI.21765	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1176	392	K	N	aaA/aaT	8,42	1	0,01	probably_damaging	1	neutral	0,59	neutral	3,84	deleterious	-5,7	deleterious	-4,5	high_impact	5,22	damaging	0,31	damaging	0,15	deleterious	3,98	23,6	0,3	0,45	disease	0,89	disease	0,83	disease	0,7	disease	0,78	6	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,32	high_impact	3,57	0,44	0,8	27,69	7,26	P	0,81	P	0,63	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13512	13512	A	C	MI.21766	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1176	392	K	N	aaA/aaC	8,42	1	0,01	probably_damaging	1	neutral	0,59	neutral	3,84	deleterious	-5,7	deleterious	-4,5	high_impact	5,22	damaging	0,31	damaging	0,15	deleterious	3,9	23,5	0,3	0,45	disease	0,89	disease	0,83	disease	0,7	disease	0,78	6	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,32	high_impact	3,57	0,44	0,8	27,69	7,26	P	0,8	P	0,63	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13513	13513	G	T	MI.21767	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1177	393	D	Y	Gac/Tac	4,52	1	0	probably_damaging	1	neutral	1	neutral	4,56	neutral	-2,85	deleterious	-8,09	high_impact	4,7	damaging	0,24	neutral	0,32	deleterious	4	23,6	0,25	0,45	disease	0,85	disease	0,94	disease	0,79	disease	0,88	8	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,91	low_impact	-3,6	high_impact	1,89	high_impact	3,09	0,33	0,8	28,19	7,12	P	0,82	P	0,99	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13513	13513	G	A	MI.21768	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1177	393	D	N	Gac/Aac	4,52	1	0	probably_damaging	1	neutral	0,32	neutral	4,5	deleterious	-3,73	deleterious	-4,5	high_impact	4,7	damaging	0,03	neutral	0,44	deleterious	4,36	24,1	0,45	0,55	disease	0,82	disease	0,85	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,05	high_impact	3,09	0,8	0,85	28,19	7,12	P	0,97	P	0,98	disease_causing_automatic	1	0,41	rs267606897	Pathogenic|Pathogenic|Pathogenic|Pathogenic	Juvenile_myopathy,_encephalopathy,_lactic_acidosis_AND_stroke|Leigh_syndrome_due_to_mitochondrial_complex_I_deficiency|Leigh_syndrome|not_provided	RCV000010345.4|RCV000010346.3|RCV000144016.2|RCV000224472.1	MedGen:OMIM:Orphanet:SNOMED_CT|MedGen|MedGen:OMIM:Orphanet:SNOMED_CT|MedGen	.	.	.	.	G13513A	Leigh Disease/MELAS/LHON-MELAS Overlap Syndrome	-	+	Cfrm	30
chrM	13513	13513	G	C	MI.21769	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1177	393	D	H	Gac/Cac	4,52	1	0	probably_damaging	1	neutral	0,53	neutral	4,51	deleterious	-4,65	deleterious	-6,29	medium_impact	3,42	damaging	0,25	neutral	0,31	deleterious	3,69	23,3	0,28	0,45	disease	0,87	disease	0,87	disease	0,79	disease	0,85	7	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,89	low_impact	-3,6	medium_impact	0,26	medium_impact	1,92	0,44	0,8	28,19	7,12	P	0,89	P	0,99	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6049	6049	G	T	MI.2177	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	146	49	G	V	gGt/gTt	5,22	1	0	probably_damaging	0,9	deleterious	0,01	neutral	2,95	neutral	-2,61	deleterious	-4,64	medium_impact	2,75	neutral	0,61	damaging	0,08	deleterious	3,62	23,2	0,33	0,55	neutral	0,38	disease	0,92	neutral	0,46	disease	0,73	5	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,8	low_impact	-1,65	medium_impact	-0,92	medium_impact	1,44	0,47	0,9	7,99	32,29	N	0,38	N	0,93	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13514	13514	A	G	MI.21770	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1178	393	D	G	gAc/gGc	9,11	1	0	probably_damaging	1	neutral	0,34	neutral	4,5	deleterious	-4,16	deleterious	-6,29	high_impact	4,24	damaging	0,21	neutral	0,44	deleterious	4,01	23,6	0,27	0,45	disease	0,88	disease	0,89	disease	0,79	disease	0,85	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,07	high_impact	2,67	0,28	0,8	28,19	7,12	P	0,95	P	0,98	disease_causing_automatic	1	0,28	rs587776440	Pathogenic	Leigh_syndrome	RCV000144017.2	MedGen:OMIM:Orphanet:SNOMED_CT	papillary thyroid carcinoma	.	.	.	A13514G	LeighDisease/MELAS	-	+	Cfrm	12
chrM	13514	13514	A	T	MI.21771	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1178	393	D	V	gAc/gTc	9,11	1	0	probably_damaging	1	neutral	0,51	neutral	4,59	neutral	-2,34	deleterious	-8,09	high_impact	4,7	damaging	0,16	neutral	0,36	deleterious	3,76	23,3	0,23	0,45	disease	0,69	disease	0,93	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	0,24	high_impact	3,09	0,31	0,8	28,19	7,12	P	0,92	P	0,99	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13514	13514	A	C	MI.21772	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1178	393	D	A	gAc/gCc	9,11	1	0	probably_damaging	1	neutral	0,55	neutral	4,58	neutral	-2,56	deleterious	-7,19	high_impact	4,14	damaging	0,29	neutral	0,46	deleterious	3,66	23,2	0,25	0,45	disease	0,62	disease	0,83	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,28	high_impact	2,58	0,41	0,8	28,19	7,12	P	0,92	P	0,94	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13515	13515	C	A	MI.21773	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1179	393	D	E	gaC/gaA	8,42	1	0	probably_damaging	1	neutral	0,29	neutral	4,52	neutral	-1,1	deleterious	-3,6	medium_impact	2,44	damaging	0,24	neutral	0,38	deleterious	4,29	24	0,37	0,5	disease	0,6	disease	0,82	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,02	medium_impact	1,03	0,62	0,8	28,19	7,12	P	0,93	P	0,91	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13515	13515	C	G	MI.21774	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1179	393	D	E	gaC/gaG	8,42	1	0	probably_damaging	1	neutral	0,29	neutral	4,52	neutral	-1,1	deleterious	-3,6	medium_impact	2,44	damaging	0,24	neutral	0,38	deleterious	3,99	23,6	0,37	0,5	disease	0,6	disease	0,82	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,02	medium_impact	1,03	0,62	0,8	28,19	7,12	P	0,93	P	0,91	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13516	13516	C	G	MI.21775	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1180	394	H	D	Cac/Gac	-0,06	0	0	benign	0	neutral	0,27	neutral	4,64	neutral	-0,23	neutral	-1,01	neutral_impact	0,14	neutral	0,68	neutral	0,5	deleterious	1,95	15,91	0,24	0,45	disease	0,56	disease	0,68	disease	0,58	disease	0,67	3	neutral	0,73	deleterious	0,64	neutral	-6	neutral	0,27	high_impact	2,1	medium_impact	-0,01	low_impact	-1,08	0,75	0,85	19,57	15,84	N	0,33	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13516	13516	C	A	MI.21776	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1180	394	H	N	Cac/Aac	-0,06	0	0	benign	0	neutral	0,36	neutral	4,7	neutral	0,28	neutral	-0,18	neutral_impact	-0,34	neutral	0,74	neutral	0,68	deleterious	2,08	16,74	0,43	0,55	disease	0,58	disease	0,63	neutral	0,38	neutral	0,46	1	neutral	0,64	deleterious	0,68	neutral	-6	neutral	0,24	high_impact	2,1	medium_impact	0,1	low_impact	-1,51	0,73	0,85	19,57	15,84	N	0,36	N	0,4	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13516	13516	C	T	MI.21777	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1180	394	H	Y	Cac/Tac	-0,06	0	0	benign	0	neutral	1	neutral	4,78	neutral	2,52	neutral	1,44	neutral_impact	-0,72	neutral	0,74	neutral	0,65	deleterious	1,81	15,06	0,43	0,55	neutral	0,35	disease	0,58	neutral	0,46	neutral	0,47	1	neutral	0	deleterious	1	neutral	-6	neutral	0,2	high_impact	2,1	high_impact	1,89	low_impact	-1,86	0,49	0,8	19,57	15,84	N	0,27	N	0,22	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13517	13517	A	C	MI.21778	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1181	394	H	P	cAc/cCc	0,17	0	0	benign	0	neutral	0,23	neutral	4,65	neutral	-0,35	neutral	0,11	neutral_impact	-1,04	neutral	0,89	neutral	0,93	deleterious	0,15	4,14	0,29	0,45	disease	0,61	disease	0,82	neutral	0,42	disease	0,57	1	neutral	0,77	deleterious	0,62	neutral	-6	neutral	0,32	high_impact	2,1	medium_impact	-0,06	low_impact	-2,15	0,58	0,8	19,57	15,84	N	0,32	N	0,4	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13517	13517	A	T	MI.21779	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1181	394	H	L	cAc/cTc	0,17	0	0	benign	0	neutral	0,68	neutral	4,87	neutral	3,91	neutral	5,42	neutral_impact	-3,25	neutral	0,86	neutral	0,97	neutral	-0,7	0,07	0,32	0,5	disease	0,55	neutral	0,41	neutral	0,2	disease	0,63	3	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,18	high_impact	2,1	medium_impact	0,41	low_impact	-4,17	0,36	0,8	19,57	15,84	N	0,3	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6049	6049	G	C	MI.2178	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	146	49	G	A	gGt/gCt	5,22	1	0	benign	0,19	deleterious	0,02	neutral	2,88	neutral	-1,56	deleterious	-3,05	medium_impact	3,29	neutral	0,69	damaging	0,1	deleterious	3	22,2	0,49	0,55	neutral	0,37	disease	0,82	neutral	0,37	disease	0,54	1	neutral	0,98	neutral	0,42	deleterious	1	deleterious	0,49	medium_impact	-0,16	medium_impact	-0,75	medium_impact	1,94	0,68	0,9	7,99	32,29	N	0,48	N	0,64	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13517	13517	A	G	MI.21780	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1181	394	H	R	cAc/cGc	0,17	0	0	benign	0	neutral	0,4	neutral	4,65	neutral	0,13	neutral	0,6	neutral_impact	-0,4	neutral	0,73	neutral	0,53	neutral	1,1	11,2	0,46	0,55	neutral	0,49	disease	0,68	neutral	0,5	neutral	0,48	0	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,27	high_impact	2,1	medium_impact	0,14	low_impact	-1,57	0,42	0,8	19,57	15,84	N	0,32	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13518	13518	C	G	MI.21781	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1182	394	H	Q	caC/caG	0,63	0	0	benign	0	neutral	0,35	neutral	4,65	neutral	0,41	neutral	0,65	neutral_impact	-0,4	neutral	0,76	neutral	0,75	neutral	1,65	14,13	0,55	0,6	disease	0,62	neutral	0,4	neutral	0,46	disease	0,62	2	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,23	high_impact	2,1	medium_impact	0,08	low_impact	-1,57	0,68	0,85	19,57	15,84	N	0,38	N	0,35	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13518	13518	C	A	MI.21782	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1182	394	H	Q	caC/caA	0,63	0	0	benign	0	neutral	0,35	neutral	4,65	neutral	0,41	neutral	0,65	neutral_impact	-0,4	neutral	0,76	neutral	0,75	deleterious	2,05	16,55	0,55	0,6	disease	0,62	neutral	0,4	neutral	0,46	disease	0,62	2	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,23	high_impact	2,1	medium_impact	0,08	low_impact	-1,57	0,68	0,85	19,57	15,84	N	0,39	N	0,35	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13519	13519	A	G	MI.21783	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1183	395	I	V	Atc/Gtc	-6,71	0	0	probably_damaging	1	neutral	0,53	neutral	4,59	neutral	-1,19	neutral	-0,9	medium_impact	3,13	damaging	0,38	damaging	0,1	deleterious	3,01	22,3	0,48	0,55	disease	0,55	disease	0,56	disease	0,61	disease	0,64	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,26	medium_impact	1,66	0,68	0,85	29,19	7,16	N	0,46	N	0,74	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13519	13519	A	C	MI.21784	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1183	395	I	L	Atc/Ctc	-6,71	0	0	probably_damaging	1	neutral	0,87	neutral	4,57	neutral	-1,15	neutral	-1,8	medium_impact	2,47	damaging	0,4	damaging	0,1	deleterious	3,74	23,3	0,27	0,45	disease	0,53	disease	0,75	disease	0,56	disease	0,65	3	deleterious	1	neutral	0,44	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,69	medium_impact	1,05	0,69	0,85	29,19	7,16	N	0,41	N	0,86	polymorphism	0,98	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13519	13519	A	T	MI.21785	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1183	395	I	F	Atc/Ttc	-6,71	0	0	probably_damaging	1	neutral	0,91	neutral	4,31	deleterious	-3,24	deleterious	-3,6	medium_impact	3,23	damaging	0,39	damaging	0,05	deleterious	3,75	23,3	0,19	0,45	disease	0,77	disease	0,86	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,46	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	0,79	medium_impact	1,75	0,83	0,85	29,19	7,16	N	0,37	N	0,96	disease_causing	0,66	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13520	13520	T	G	MI.21786	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1184	395	I	S	aTc/aGc	8,42	1	0	probably_damaging	1	neutral	0,73	neutral	4,35	deleterious	-4,71	deleterious	-5,4	high_impact	4,46	damaging	0,4	damaging	0,13	deleterious	4,4	24,1	0,18	0,45	disease	0,88	disease	0,89	disease	0,68	disease	0,8	6	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	0,47	high_impact	2,87	0,56	0,8	29,19	7,16	P	0,69	P	0,96	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13520	13520	T	C	MI.21787	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1184	395	I	T	aTc/aCc	8,42	1	0	probably_damaging	1	neutral	0,55	neutral	4,34	deleterious	-3,74	deleterious	-4,5	high_impact	4,46	damaging	0,39	damaging	0,06	deleterious	3,53	23,1	0,26	0,45	disease	0,76	disease	0,84	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,28	high_impact	2,87	0,62	0,8	29,19	7,16	P	0,63	P	0,96	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13520	13520	T	A	MI.21788	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1184	395	I	N	aTc/aAc	8,42	1	0	probably_damaging	1	neutral	0,5	neutral	4,28	deleterious	-6,15	deleterious	-6,29	high_impact	5,01	damaging	0,36	damaging	0,06	deleterious	4,55	24,3	0,15	0,45	disease	0,94	disease	0,89	disease	0,69	disease	0,82	6	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,23	high_impact	3,37	0,57	0,8	29,19	7,16	P	0,66	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13521	13521	C	A	MI.21789	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1185	395	I	M	atC/atA	7,27	1	0	probably_damaging	1	neutral	0,32	neutral	4,31	deleterious	-3,39	deleterious	-2,7	medium_impact	2,6	damaging	0,44	damaging	0,09	deleterious	3,97	23,6	0,27	0,45	disease	0,81	disease	0,75	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,05	medium_impact	1,17	0,77	0,85	29,19	7,16	P	0,55	P	0,76	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6049	6049	G	A	MI.2179	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	146	49	G	D	gGt/gAt	5,22	1	0	possibly_damaging	0,44	deleterious	0,01	neutral	2,82	neutral	-1,89	deleterious	-3,38	medium_impact	3,19	neutral	0,62	damaging	0,07	deleterious	3,71	23,3	0,31	0,55	disease	0,55	disease	0,92	disease	0,53	disease	0,67	3	deleterious	0,99	neutral	0,29	deleterious	4	deleterious	0,64	medium_impact	-0,66	medium_impact	-0,92	medium_impact	1,85	0,37	0,9	7,99	32,29	N	0,43	N	0,97	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13521	13521	C	G	MI.21790	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1185	395	I	M	atC/atG	7,27	1	0	probably_damaging	1	neutral	0,32	neutral	4,31	deleterious	-3,39	deleterious	-2,7	medium_impact	2,6	damaging	0,44	damaging	0,09	deleterious	3,45	23	0,27	0,45	disease	0,81	disease	0,75	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,05	medium_impact	1,17	0,77	0,85	29,19	7,16	P	0,55	P	0,76	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13522	13522	A	T	MI.21791	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1186	396	I	F	Atc/Ttc	-3,73	0	0	probably_damaging	1	neutral	0,77	neutral	4,45	neutral	-1,26	deleterious	-3,6	medium_impact	2,4	damaging	0,54	damaging	0,07	deleterious	3,88	23,5	0,33	0,5	neutral	0,4	disease	0,85	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,52	medium_impact	0,99	0,82	0,85	19,9	7,02	N	0,21	N	0,96	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13522	13522	A	G	MI.21792	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1186	396	I	V	Atc/Gtc	-3,73	0	0	probably_damaging	1	neutral	0,49	neutral	4,34	neutral	-2,77	neutral	-0,9	low_impact	1,94	damaging	0,53	damaging	0,21	deleterious	3,17	22,7	0,53	0,6	disease	0,57	neutral	0,5	disease	0,56	disease	0,56	1	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,22	medium_impact	0,57	0,63	0,8	19,9	7,02	N	0,33	N	0,74	polymorphism	0,68	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13522	13522	A	C	MI.21793	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1186	396	I	L	Atc/Ctc	-3,73	0	0	probably_damaging	1	neutral	0,66	neutral	5,36	neutral	1,96	neutral	-1,8	neutral_impact	-0,11	damaging	0,49	damaging	0,13	deleterious	3,9	23,5	0,33	0,5	neutral	0,33	neutral	0,5	disease	0,52	neutral	0,42	2	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	0,39	low_impact	-1,3	0,81	0,85	19,9	7,02	N	0,3	N	0,86	disease_causing	0,52	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13523	13523	T	C	MI.21794	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1187	396	I	T	aTc/aCc	4,29	0,99	0	probably_damaging	1	neutral	0,43	neutral	4,3	deleterious	-4,86	deleterious	-4,5	medium_impact	3,48	damaging	0,53	damaging	0,05	deleterious	3,57	23,1	0,32	0,5	disease	0,79	disease	0,83	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,17	medium_impact	1,98	0,6	0,8	19,9	7,02	N	0,4	N	0,96	disease_causing	0,99	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13523	13523	T	A	MI.21795	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1187	396	I	N	aTc/aAc	4,29	0,99	0	probably_damaging	1	neutral	0,33	neutral	4,29	deleterious	-6,92	deleterious	-6,29	high_impact	4,29	damaging	0,52	damaging	0,05	deleterious	4,61	24,4	0,19	0,45	disease	0,91	disease	0,88	disease	0,67	disease	0,81	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,06	high_impact	2,72	0,57	0,8	19,9	7,02	N	0,46	N	0,99	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13523	13523	T	G	MI.21796	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1187	396	I	S	aTc/aGc	4,29	0,99	0	probably_damaging	1	neutral	0,55	neutral	4,29	deleterious	-5,8	deleterious	-5,4	high_impact	3,6	damaging	0,51	damaging	0,11	deleterious	4,43	24,2	0,2	0,45	disease	0,71	disease	0,89	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,28	high_impact	2,09	0,56	0,8	19,9	7,02	N	0,45	N	0,96	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13524	13524	C	G	MI.21797	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1188	396	I	M	atC/atG	5,67	1	0	probably_damaging	1	neutral	0,24	neutral	4,35	neutral	-2,53	deleterious	-2,7	medium_impact	2,66	damaging	0,56	damaging	0,13	deleterious	3,49	23,1	0,38	0,5	disease	0,74	disease	0,7	disease	0,55	disease	0,63	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	-0,04	medium_impact	1,23	0,83	0,85	19,9	7,02	N	0,47	N	0,76	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13524	13524	C	A	MI.21798	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1188	396	I	M	atC/atA	5,67	1	0	probably_damaging	1	neutral	0,24	neutral	4,35	neutral	-2,53	deleterious	-2,7	medium_impact	2,66	damaging	0,56	damaging	0,13	deleterious	3,96	23,6	0,38	0,5	disease	0,74	disease	0,7	disease	0,55	disease	0,63	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	-0,04	medium_impact	1,23	0,83	0,85	19,9	7,02	N	0,47	N	0,76	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13525	13525	G	C	MI.21799	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1189	397	E	Q	Gaa/Caa	-3,27	0	0	probably_damaging	1	neutral	0,3	neutral	4,54	neutral	-1,19	deleterious	-2,7	high_impact	3,76	damaging	0,3	damaging	0,06	deleterious	3,44	23	0,58	0,65	disease	0,53	disease	0,79	disease	0,58	disease	0,67	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,03	high_impact	2,23	0,8	0,85	29,19	7,19	P	0,5	N	0,88	disease_causing	0,97	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8629	8629	A	G	MI.218	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	103	35	K	E	Aaa/Gaa	-14,22	0	0	benign	0,19	neutral	0,27	neutral	4,37	neutral	-0,51	neutral	-1,17	neutral_impact	0,55	neutral	0,91	neutral	0,73	deleterious	0,75	9,15	0,5	0,65	neutral	0,44	disease	0,53	disease	0,52	disease	0,61	2	neutral	0,68	deleterious	0,54	neutral	-6	neutral	0,41	medium_impact	-0,16	medium_impact	0,05	medium_impact	-0,63	0,68	0,9	20,35	18,29	N	0,36	N	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6051	6051	A	T	MI.2180	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	148	50	N	Y	Aac/Tac	-6,58	0	0	possibly_damaging	0,55	deleterious	0	neutral	2,82	neutral	-2,13	deleterious	-2,91	medium_impact	3,42	neutral	0,61	neutral	0,63	deleterious	3,54	23,1	0,48	0,55	disease	0,64	disease	0,87	disease	0,65	disease	0,78	6	deleterious	1	neutral	0,23	deleterious	4	deleterious	0,54	medium_impact	-0,84	low_impact	-1,48	high_impact	2,06	0,34	0,9	12,87	67,9	N	0,34	N	0,75	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13525	13525	G	A	MI.21800	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1189	397	E	K	Gaa/Aaa	-3,27	0	0	probably_damaging	1	neutral	0,32	neutral	4,53	neutral	-1,99	deleterious	-3,6	high_impact	3,68	damaging	0,28	damaging	0,04	deleterious	4,62	24,5	0,43	0,55	disease	0,63	disease	0,89	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,05	high_impact	2,16	0,75	0,85	29,19	7,19	P	0,73	P	0,99	disease_causing	0,99	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13526	13526	A	G	MI.21801	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1190	397	E	G	gAa/gGa	7,04	1	0	probably_damaging	1	neutral	0,34	neutral	4,52	neutral	-2,56	deleterious	-6,29	medium_impact	3,19	damaging	0,3	damaging	0,08	deleterious	4,4	24,1	0,41	0,5	disease	0,67	disease	0,82	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,07	medium_impact	1,71	0,4	0,8	29,19	7,19	P	0,69	P	0,52	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13526	13526	A	C	MI.21802	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1190	397	E	A	gAa/gCa	7,04	1	0	probably_damaging	1	neutral	0,53	neutral	4,59	neutral	-1,34	deleterious	-5,4	medium_impact	2,93	damaging	0,31	damaging	0,1	deleterious	3,85	23,4	0,38	0,5	disease	0,59	disease	0,73	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,26	medium_impact	1,47	0,57	0,8	29,19	7,19	P	0,7	P	0,74	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13526	13526	A	T	MI.21803	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1190	397	E	V	gAa/gTa	7,04	1	0	probably_damaging	1	neutral	0,51	neutral	4,54	neutral	-2,38	deleterious	-6,29	high_impact	3,64	damaging	0,27	damaging	0,07	deleterious	4,39	24,1	0,33	0,5	disease	0,68	disease	0,89	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,24	high_impact	2,12	0,59	0,8	29,19	7,19	P	0,83	P	0,82	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13527	13527	A	C	MI.21804	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1191	397	E	D	gaA/gaC	8,42	1	0,01	probably_damaging	1	neutral	0,22	neutral	4,5	neutral	-2,38	deleterious	-2,7	medium_impact	3,4	damaging	0,27	damaging	0,06	deleterious	3,8	23,4	0,53	0,6	disease	0,77	disease	0,77	disease	0,54	disease	0,68	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	-0,07	medium_impact	1,9	0,71	0,85	29,19	7,19	P	0,87	P	0,86	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13527	13527	A	T	MI.21805	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1191	397	E	D	gaA/gaT	8,42	1	0,01	probably_damaging	1	neutral	0,22	neutral	4,5	neutral	-2,38	deleterious	-2,7	medium_impact	3,4	damaging	0,27	damaging	0,06	deleterious	3,9	23,5	0,53	0,6	disease	0,77	disease	0,77	disease	0,54	disease	0,68	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	-0,07	medium_impact	1,9	0,71	0,85	29,19	7,19	P	0,88	P	0,86	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13528	13528	A	C	MI.21806	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1192	398	T	P	Acc/Ccc	0,63	0,09	0	probably_damaging	0,97	neutral	0,25	neutral	3,67	deleterious	-3,23	deleterious	-2,96	medium_impact	2,72	neutral	0,65	neutral	0,36	deleterious	3,53	23,1	0,21	0,45	NA	NA	disease	0,82	disease	0,68	disease	0,78	6	neutral	0,98	neutral	0,14	deleterious	1	deleterious	0,88	low_impact	-2,18	medium_impact	-0,03	medium_impact	1,28	0,68	0,85	3,65	10,2	N	0,36	N	0,59	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13528	13528	A	T	MI.21807	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1192	398	T	S	Acc/Tcc	0,63	0,09	0	benign	0,26	neutral	0,55	neutral	3,81	neutral	0,21	neutral	-0,17	neutral_impact	0,08	neutral	0,85	neutral	0,99	deleterious	2	16,2	0,57	0,65	NA	NA	neutral	0,29	neutral	0,25	neutral	0,18	6	neutral	0,34	deleterious	0,65	neutral	-6	deleterious	0,76	medium_impact	-0,32	medium_impact	0,28	low_impact	-1,13	0,77	0,85	3,65	10,2	N	0,36	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13528	13528	A	G	MI.21808	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1192	398	T	A	Acc/Gcc	0,63	0,09	0	benign	0,12	neutral	0,66	neutral	3,95	neutral	1,43	neutral	-0,85	neutral_impact	-0,86	neutral	0,84	neutral	0,99	deleterious	0,76	9,24	0,62	0,65	NA	NA	neutral	0,05	neutral	0,21	neutral	0,18	6	neutral	0,23	deleterious	0,77	neutral	-6	deleterious	0,69	medium_impact	0,08	medium_impact	0,39	low_impact	-1,99	0,56	0,8	3,65	10,2	N	0,45	N	0	polymorphism	1	0,01	rs55882959	.	.	.	.	.	.	.	.	A13528G	LHON-like,LHON,MELAS	+	-	Reported	4
chrM	13529	13529	C	A	MI.21809	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1193	398	T	N	aCc/aAc	-3,73	0	0	possibly_damaging	0,88	neutral	0,4	neutral	3,71	neutral	-1,61	neutral	-2,17	low_impact	1	neutral	0,75	neutral	0,76	deleterious	3,85	23,4	0,64	0,7	NA	NA	disease	0,66	neutral	0,43	neutral	0,5	0	neutral	0,88	neutral	0,26	neutral	-3	deleterious	0,8	low_impact	-1,57	medium_impact	0,14	medium_impact	-0,29	0,77	0,85	3,65	10,2	N	0,3	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6051	6051	A	C	MI.2181	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	148	50	N	H	Aac/Cac	-6,58	0	0	possibly_damaging	0,62	deleterious	0	neutral	2,82	neutral	-1,28	neutral	-1,6	medium_impact	3,42	neutral	0,63	neutral	0,53	deleterious	2,92	21,9	0,74	0,75	disease	0,53	disease	0,78	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,19	deleterious	4	deleterious	0,5	medium_impact	-0,96	low_impact	-1,48	high_impact	2,06	0,41	0,9	12,87	67,9	N	0,35	N	0,39	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13529	13529	C	G	MI.21810	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1193	398	T	S	aCc/aGc	-3,73	0	0	benign	0,26	neutral	0,55	neutral	3,81	neutral	0,21	neutral	-0,17	neutral_impact	0,08	neutral	0,85	neutral	0,99	deleterious	2,29	18,12	0,57	0,65	NA	NA	neutral	0,29	neutral	0,25	neutral	0,18	6	neutral	0,34	deleterious	0,65	neutral	-6	deleterious	0,76	medium_impact	-0,32	medium_impact	0,28	low_impact	-1,13	0,77	0,85	3,65	10,2	N	0,3	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13529	13529	C	T	MI.21811	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1193	398	T	I	aCc/aTc	-3,73	0	0	probably_damaging	0,94	neutral	0,44	neutral	3,7	neutral	-1,85	deleterious	-3,28	low_impact	1,07	neutral	0,77	neutral	0,62	deleterious	3,98	23,6	0,54	0,6	NA	NA	disease	0,66	disease	0,53	disease	0,53	1	neutral	0,94	neutral	0,25	neutral	-2	deleterious	0,82	low_impact	-1,88	medium_impact	0,18	medium_impact	-0,23	0,58	0,8	3,65	10,2	N	0,24	N	0,52	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13531	13531	G	T	MI.21812	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1195	399	A	S	Gca/Tca	-8,08	0	0	possibly_damaging	0,81	neutral	0,43	neutral	3,41	deleterious	-3,22	neutral	-2,04	neutral_impact	0,52	neutral	0,84	neutral	0,66	deleterious	3,81	23,4	0,55	0,6	NA	NA	disease	0,54	neutral	0,48	neutral	0,5	0	neutral	0,81	neutral	0,31	neutral	-3	deleterious	0,83	low_impact	-1,34	medium_impact	0,17	medium_impact	-0,73	0,89	0,9	25,7	16,15	N	0,26	N	0,55	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13531	13531	G	A	MI.21813	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1195	399	A	T	Gca/Aca	-8,08	0	0	benign	0,18	neutral	0,4	neutral	3,35	deleterious	-3,41	deleterious	-2,5	neutral_impact	0,78	neutral	0,86	neutral	0,73	deleterious	3,24	22,8	0,59	0,65	NA	NA	disease	0,54	disease	0,53	neutral	0,49	0	neutral	0,52	deleterious	0,61	neutral	-6	deleterious	0,76	medium_impact	-0,12	medium_impact	0,14	medium_impact	-0,49	0,7	0,85	25,7	16,15	N	0,29	N	0,3	polymorphism	1	0,06	.	.	.	.	.	.	COSM1155542	.	.	.	.	.	.	.	.
chrM	13531	13531	G	C	MI.21814	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1195	399	A	P	Gca/Cca	-8,08	0	0	probably_damaging	0,98	neutral	0,2	neutral	3,29	deleterious	-6,21	deleterious	-3,6	medium_impact	2,89	neutral	0,6	neutral	0,38	deleterious	3,98	23,6	0,17	0,45	NA	NA	disease	0,85	disease	0,67	disease	0,79	6	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,9	low_impact	-2,35	medium_impact	-0,1	medium_impact	1,44	0,79	0,85	25,7	16,15	N	0,3	N	0,89	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13532	13532	C	G	MI.21815	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1196	399	A	G	gCa/gGa	-0,52	0	0	possibly_damaging	0,86	neutral	0,33	neutral	3,35	deleterious	-3,03	deleterious	-3,2	low_impact	1,37	neutral	0,78	neutral	0,63	deleterious	4,07	23,7	0,32	0,5	NA	NA	disease	0,58	neutral	0,49	neutral	0,49	0	neutral	0,88	neutral	0,24	neutral	-3	deleterious	0,81	low_impact	-1,5	medium_impact	0,06	medium_impact	0,05	0,82	0,85	25,7	16,15	N	0,28	N	0,6	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13532	13532	C	A	MI.21816	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1196	399	A	E	gCa/gAa	-0,52	0	0	probably_damaging	0,96	neutral	0,28	neutral	3,29	deleterious	-5,85	deleterious	-3,6	medium_impact	2,89	neutral	0,72	neutral	0,51	deleterious	4,57	24,4	0,17	0,45	NA	NA	disease	0,8	disease	0,67	disease	0,76	5	neutral	0,97	neutral	0,16	deleterious	1	deleterious	0,87	low_impact	-2,06	medium_impact	0,01	medium_impact	1,44	0,72	0,85	25,7	16,15	N	0,34	N	0,89	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13532	13532	C	T	MI.21817	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1196	399	A	V	gCa/gTa	-0,52	0	0	possibly_damaging	0,61	neutral	0,5	neutral	3,43	neutral	-2,6	neutral	-2,01	low_impact	0,84	neutral	0,84	neutral	0,79	deleterious	3,38	22,9	0,52	0,6	NA	NA	disease	0,55	neutral	0,43	neutral	0,49	0	neutral	0,59	neutral	0,45	neutral	-3	deleterious	0,78	medium_impact	-0,93	medium_impact	0,23	medium_impact	-0,44	0,72	0,85	25,7	16,15	N	0,25	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	COSM3307733	.	.	.	.	.	.	.	.
chrM	13534	13534	A	T	MI.21818	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1198	400	N	Y	Aac/Tac	-1,89	0	0	probably_damaging	0,94	neutral	1	neutral	3,79	neutral	0,51	deleterious	-6,21	low_impact	1,79	neutral	0,72	neutral	0,55	deleterious	3,73	23,3	0,53	0,6	NA	NA	disease	0,79	disease	0,71	disease	0,57	1	neutral	0,94	deleterious	0,53	neutral	-2	deleterious	0,76	low_impact	-1,88	high_impact	1,89	medium_impact	0,43	0,48	0,8	6,97	13,86	N	0,2	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13534	13534	A	C	MI.21819	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1198	400	N	H	Aac/Cac	-1,89	0	0	probably_damaging	0,94	neutral	0,53	neutral	3,74	neutral	-0,81	deleterious	-3,96	high_impact	3,6	neutral	0,71	neutral	0,41	deleterious	3,03	22,3	0,56	0,6	NA	NA	disease	0,74	disease	0,77	disease	0,72	4	neutral	0,94	neutral	0,3	deleterious	2	deleterious	0,76	low_impact	-1,88	medium_impact	0,26	high_impact	2,09	0,54	0,8	6,97	13,86	N	0,34	N	0,85	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6051	6051	A	G	MI.2182	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	148	50	N	D	Aac/Gac	-6,58	0	0	benign	0	neutral	1	neutral	2,99	neutral	2,12	neutral	1,72	neutral_impact	0,02	neutral	0,73	neutral	0,93	neutral	-0,7	0,07	0,81	0,85	neutral	0,19	neutral	0,12	neutral	0,29	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,07	high_impact	1,86	low_impact	-1,08	0,54	0,9	12,87	67,9	N	0,4	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13534	13534	A	G	MI.21820	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1198	400	N	D	Aac/Gac	-1,89	0	0	benign	0,42	neutral	0,24	neutral	3,74	neutral	-0,65	deleterious	-3,79	medium_impact	3,05	neutral	0,73	neutral	0,42	deleterious	2,15	17,18	0,62	0,65	NA	NA	disease	0,77	disease	0,65	disease	0,68	4	neutral	0,72	neutral	0,41	neutral	-3	deleterious	0,5	medium_impact	-0,61	medium_impact	-0,04	medium_impact	1,58	0,68	0,85	6,97	13,86	N	0,34	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13535	13535	A	G	MI.21821	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1199	400	N	S	aAc/aGc	5,44	0,69	0	benign	0,04	neutral	0,46	neutral	3,85	neutral	0,66	deleterious	-3,29	low_impact	0,9	neutral	0,78	neutral	0,81	neutral	1,12	11,32	0,65	0,7	NA	NA	disease	0,71	disease	0,59	disease	0,54	1	neutral	0,51	deleterious	0,71	neutral	-6	neutral	0,25	medium_impact	0,57	medium_impact	0,19	medium_impact	-0,38	0,48	0,8	6,97	13,86	N	0,34	N	0,81	polymorphism	0,86	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13535	13535	A	T	MI.21822	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1199	400	N	I	aAc/aTc	5,44	0,69	0	possibly_damaging	0,84	neutral	0,43	neutral	3,79	neutral	0,31	deleterious	-6,82	medium_impact	2,54	neutral	0,74	neutral	0,6	deleterious	3,6	23,2	0,52	0,6	NA	NA	disease	0,89	disease	0,66	disease	0,69	4	neutral	0,84	neutral	0,3	NA	0	deleterious	0,73	low_impact	-1,43	medium_impact	0,17	medium_impact	1,12	0,48	0,8	6,97	13,86	N	0,4	N	0,98	disease_causing	0,61	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13535	13535	A	C	MI.21823	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1199	400	N	T	aAc/aCc	5,44	0,69	0	benign	0,42	neutral	0,45	neutral	3,83	neutral	0,35	deleterious	-3,88	low_impact	1,64	neutral	0,81	neutral	0,93	deleterious	0,55	7,79	0,55	0,6	NA	NA	disease	0,72	disease	0,53	neutral	0,5	0	neutral	0,5	deleterious	0,52	neutral	-6	neutral	0,4	medium_impact	-0,61	medium_impact	0,18	medium_impact	0,3	0,52	0,8	6,97	13,86	N	0,33	N	0,6	polymorphism	0,66	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13536	13536	C	G	MI.21824	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1200	400	N	K	aaC/aaG	1,08	0,28	0	possibly_damaging	0,56	neutral	0,34	neutral	3,75	neutral	-0,49	deleterious	-4,51	high_impact	3,6	neutral	0,71	neutral	0,4	deleterious	2,29	18,09	0,64	0,7	NA	NA	disease	0,82	disease	0,76	disease	0,77	5	neutral	0,66	neutral	0,39	deleterious	1	deleterious	0,58	medium_impact	-0,85	medium_impact	0,07	high_impact	2,09	0,52	0,8	6,97	13,86	N	0,4	N	0,95	polymorphism	0,71	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13536	13536	C	A	MI.21825	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1200	400	N	K	aaC/aaA	1,08	0,28	0	possibly_damaging	0,56	neutral	0,34	neutral	3,75	neutral	-0,49	deleterious	-4,51	high_impact	3,6	neutral	0,71	neutral	0,4	deleterious	2,79	21,3	0,64	0,7	NA	NA	disease	0,82	disease	0,76	disease	0,77	5	neutral	0,66	neutral	0,39	deleterious	1	deleterious	0,58	medium_impact	-0,85	medium_impact	0,07	high_impact	2,09	0,52	0,8	6,97	13,86	N	0,4	N	0,95	polymorphism	0,71	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13537	13537	A	C	MI.21826	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1201	401	M	L	Ata/Cta	-1,67	0	0	benign	0,04	neutral	0,75	neutral	3,88	neutral	1,34	neutral	-0,38	low_impact	0,88	neutral	0,84	neutral	0,8	deleterious	3,03	22,3	0,57	0,65	NA	NA	disease	0,51	disease	0,58	disease	0,52	0	neutral	0,19	deleterious	0,86	neutral	-6	deleterious	0,51	medium_impact	0,57	medium_impact	0,5	medium_impact	-0,4	0,59	0,8	9,45	13,07	N	0,26	N	0,48	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13537	13537	A	G	MI.21827	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1201	401	M	V	Ata/Gta	-1,67	0	0	benign	0,06	neutral	0,52	neutral	3,79	neutral	0,54	neutral	0,12	low_impact	1,83	neutral	0,82	neutral	0,87	deleterious	2,54	19,72	0,61	0,65	NA	NA	neutral	0,47	disease	0,61	neutral	0,41	2	neutral	0,43	deleterious	0,73	neutral	-6	deleterious	0,55	medium_impact	0,39	medium_impact	0,25	medium_impact	0,47	0,62	0,8	9,45	13,07	N	0,33	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13537	13537	A	T	MI.21828	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1201	401	M	L	Ata/Tta	-1,67	0	0	benign	0,04	neutral	0,75	neutral	3,88	neutral	1,34	neutral	-0,38	low_impact	0,88	neutral	0,84	neutral	0,8	deleterious	3,1	22,5	0,57	0,65	NA	NA	disease	0,51	disease	0,58	disease	0,52	0	neutral	0,19	deleterious	0,86	neutral	-6	deleterious	0,51	medium_impact	0,57	medium_impact	0,5	medium_impact	-0,4	0,59	0,8	9,45	13,07	N	0,27	N	0,48	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13538	13538	T	A	MI.21829	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1202	401	M	K	aTa/aAa	2,46	0,4	0	benign	0,16	neutral	0,28	neutral	3,78	neutral	0,17	neutral	-0,74	medium_impact	2,56	neutral	0,71	neutral	0,53	deleterious	4,11	23,7	0,31	0,45	NA	NA	disease	0,71	disease	0,63	disease	0,71	4	neutral	0,67	deleterious	0,56	neutral	-3	deleterious	0,76	medium_impact	-0,06	medium_impact	0,01	medium_impact	1,14	0,55	0,8	9,45	13,07	N	0,35	N	0,58	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6052	6052	A	T	MI.2183	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	149	50	N	I	aAc/aTc	5,22	1	0	benign	0,35	deleterious	0	neutral	2,8	neutral	-1,75	deleterious	-3,03	high_impact	4,22	neutral	0,62	neutral	0,62	deleterious	3,55	23,1	0,38	0,55	neutral	0,36	disease	0,87	disease	0,58	disease	0,78	6	deleterious	1	neutral	0,33	deleterious	2	neutral	0,34	medium_impact	-0,5	low_impact	-1,48	high_impact	2,8	0,2	0,9	12,87	67,9	P	0,5	N	0,7	disease_causing	0,77	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13538	13538	T	C	MI.21830	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1202	401	M	T	aTa/aCa	2,46	0,4	0	benign	0	neutral	0,44	neutral	3,8	neutral	0,22	neutral	3,42	neutral_impact	-0,75	neutral	0,85	neutral	0,94	deleterious	0,36	6,24	0,54	0,6	NA	NA	neutral	0,11	neutral	0,2	neutral	0,22	6	neutral	0,56	deleterious	0,72	neutral	-6	deleterious	0,61	high_impact	2,1	medium_impact	0,18	low_impact	-1,89	0,3	0,8	9,45	13,07	N	0,37	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13539	13539	A	C	MI.21831	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1203	401	M	I	atA/atC	2,23	0,41	0,01	benign	0,12	neutral	0,54	neutral	3,78	neutral	0,43	neutral	-0,53	low_impact	1,54	neutral	0,74	neutral	0,81	deleterious	3,42	23	0,62	0,65	NA	NA	disease	0,53	neutral	0,46	neutral	0,49	0	neutral	0,37	deleterious	0,71	neutral	-6	deleterious	0,67	medium_impact	0,08	medium_impact	0,27	medium_impact	0,2	0,57	0,8	9,45	13,07	N	0,32	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13539	13539	A	T	MI.21832	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1203	401	M	I	atA/atT	2,23	0,41	0,01	benign	0,12	neutral	0,54	neutral	3,78	neutral	0,43	neutral	-0,53	low_impact	1,54	neutral	0,74	neutral	0,81	deleterious	3,52	23,1	0,62	0,65	NA	NA	disease	0,53	neutral	0,46	neutral	0,49	0	neutral	0,37	deleterious	0,71	neutral	-6	deleterious	0,67	medium_impact	0,08	medium_impact	0,27	medium_impact	0,2	0,57	0,8	9,45	13,07	N	0,32	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13540	13540	T	A	MI.21833	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1204	402	S	T	Tca/Aca	-3,96	0	0	probably_damaging	1	neutral	0,4	neutral	3,57	neutral	-1,93	deleterious	-2,6	medium_impact	3,04	neutral	0,64	damaging	0,14	deleterious	3,82	23,4	0,39	0,5	NA	NA	disease	0,69	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,14	medium_impact	1,57	0,86	0,9	10,45	13	N	0,26	N	0,54	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13540	13540	T	C	MI.21834	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1204	402	S	P	Tca/Cca	-3,96	0	0	probably_damaging	1	neutral	0,2	neutral	3,52	deleterious	-3,21	deleterious	-4,4	high_impact	3,52	neutral	0,66	damaging	0,11	deleterious	4,09	23,7	0,19	0,45	NA	NA	disease	0,84	disease	0,81	disease	0,8	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,1	high_impact	2,01	0,64	0,8	10,45	13	N	0,38	N	0,92	polymorphism	0,98	0,09	.	.	.	.	.	head/neck tumor	.	.	.	.	.	.	.	.	.
chrM	13540	13540	T	G	MI.21835	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1204	402	S	A	Tca/Gca	-3,96	0	0	probably_damaging	0,99	neutral	0,51	neutral	3,63	neutral	-0,62	deleterious	-2,56	medium_impact	3,12	neutral	0,63	damaging	0,13	deleterious	3,81	23,4	0,5	0,6	NA	NA	disease	0,55	disease	0,7	disease	0,67	3	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,73	low_impact	-2,64	medium_impact	0,24	medium_impact	1,65	0,76	0,85	10,45	13	N	0,26	N	0,39	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13541	13541	C	G	MI.21836	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1205	402	S	W	tCa/tGa	7,27	1	0	probably_damaging	1	neutral	0,19	neutral	3,5	deleterious	-4,9	deleterious	-6,09	high_impact	4,22	neutral	0,67	damaging	0,1	deleterious	4,42	24,2	0,22	0,45	NA	NA	disease	0,89	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,12	high_impact	2,65	0,49	0,8	10,45	13	P	0,54	P	0,98	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13541	13541	C	T	MI.21837	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1205	402	S	L	tCa/tTa	7,27	1	0	probably_damaging	1	neutral	0,66	neutral	3,56	neutral	-2,77	deleterious	-5,2	high_impact	3,59	neutral	0,61	damaging	0,11	deleterious	4,72	24,6	0,33	0,5	NA	NA	disease	0,87	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,39	high_impact	2,08	0,84	0,9	10,45	13	N	0,51	P	0,93	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13543	13543	T	G	MI.21838	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1207	403	Y	D	Tac/Gac	-7,17	0	0	possibly_damaging	0,84	neutral	0,22	neutral	3,68	neutral	-1,35	deleterious	-6,47	medium_impact	2,15	neutral	0,76	neutral	0,39	deleterious	3,78	23,4	0,44	0,55	disease	0,55	disease	0,87	disease	0,78	disease	0,81	6	neutral	0,9	neutral	0,19	NA	0	deleterious	0,68	low_impact	-1,43	medium_impact	-0,07	medium_impact	0,76	0,33	0,8	5,64	10,11	N	0,33	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13543	13543	T	A	MI.21839	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1207	403	Y	N	Tac/Aac	-7,17	0	0	possibly_damaging	0,67	neutral	0,35	neutral	3,72	neutral	-0,98	deleterious	-4,93	low_impact	0,85	neutral	0,82	neutral	0,97	neutral	1,2	11,76	0,49	0,55	neutral	0,44	disease	0,67	neutral	0,4	neutral	0,48	0	neutral	0,72	neutral	0,34	neutral	-3	deleterious	0,46	low_impact	-1,04	medium_impact	0,08	medium_impact	-0,43	0,26	0,8	5,64	10,11	N	0,32	N	0,47	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6052	6052	A	G	MI.2184	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	149	50	N	S	aAc/aGc	5,22	1	0	benign	0	neutral	0,2	neutral	2,94	neutral	0,2	neutral	-0,98	low_impact	1,12	neutral	0,69	neutral	0,85	deleterious	-0,06	2,05	0,8	0,8	neutral	0,24	disease	0,67	neutral	0,38	neutral	0,48	0	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,19	high_impact	2,07	medium_impact	-0,14	medium_impact	-0,07	0,19	0,9	12,87	67,9	P	0,61	P	0,14	polymorphism	0,74	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13543	13543	T	C	MI.21840	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1207	403	Y	H	Tac/Cac	-7,17	0	0	benign	0,03	neutral	0,53	neutral	3,71	neutral	-0,27	neutral	-2,37	neutral_impact	0,79	neutral	0,8	neutral	0,88	deleterious	0,24	5,1	0,7	0,75	disease	0,63	neutral	0,31	neutral	0,35	disease	0,61	2	neutral	0,43	deleterious	0,75	neutral	-6	neutral	0,22	medium_impact	0,69	medium_impact	0,26	medium_impact	-0,48	0,43	0,8	5,64	10,11	N	0,22	N	0,7	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13544	13544	A	G	MI.21841	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1208	403	Y	C	tAc/tGc	-0,52	0	0	probably_damaging	0,94	neutral	0,18	neutral	3,62	deleterious	-5,05	deleterious	-6,54	medium_impact	3,42	neutral	0,85	neutral	0,48	deleterious	3,46	23	0,4	0,5	disease	0,65	disease	0,87	disease	0,61	disease	0,74	5	neutral	0,97	neutral	0,12	deleterious	1	deleterious	0,78	low_impact	-1,88	medium_impact	-0,13	medium_impact	1,92	0,09	0,8	5,64	10,11	N	0,35	N	0,84	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13544	13544	A	C	MI.21842	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1208	403	Y	S	tAc/tCc	-0,52	0	0	possibly_damaging	0,74	neutral	0,46	neutral	3,72	neutral	-0,34	deleterious	-5,76	medium_impact	2,06	neutral	0,8	neutral	0,75	deleterious	2,12	17	0,38	0,5	neutral	0,39	disease	0,79	neutral	0,49	disease	0,54	1	neutral	0,73	neutral	0,36	NA	0	deleterious	0,53	low_impact	-1,18	medium_impact	0,19	medium_impact	0,68	0,28	0,8	5,64	10,11	N	0,26	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13544	13544	A	T	MI.21843	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1208	403	Y	F	tAc/tTc	-0,52	0	0	possibly_damaging	0,59	neutral	0,7	neutral	3,7	neutral	-0,51	deleterious	-3,06	medium_impact	2,1	neutral	0,79	neutral	0,66	neutral	1,71	14,47	0,51	0,6	disease	0,73	disease	0,77	neutral	0,38	disease	0,58	2	neutral	0,5	deleterious	0,56	NA	0	deleterious	0,62	medium_impact	-0,9	medium_impact	0,44	medium_impact	0,72	0,33	0,8	5,64	10,11	N	0,19	N	0,57	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13546	13546	A	G	MI.21844	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1210	404	T	A	Aca/Gca	-2,81	0	0	benign	0,22	neutral	0,6	neutral	3,76	neutral	-0,24	deleterious	-3,44	low_impact	1,64	neutral	0,79	neutral	0,78	neutral	-0,07	2	0,62	0,65	neutral	0,31	neutral	0,43	disease	0,61	disease	0,5	0	neutral	0,29	deleterious	0,69	neutral	-6	neutral	0,24	medium_impact	-0,22	medium_impact	0,33	medium_impact	0,3	0,43	0,8	5,97	9,01	N	0,29	N	0,67	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13546	13546	A	T	MI.21845	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1210	404	T	S	Aca/Tca	-2,81	0	0	possibly_damaging	0,46	neutral	0,44	neutral	3,82	neutral	-0,56	deleterious	-2,97	low_impact	1,17	neutral	0,83	neutral	0,6	deleterious	0,42	6,8	0,47	0,55	neutral	0,44	neutral	0,48	disease	0,59	neutral	0,5	0	neutral	0,53	deleterious	0,49	neutral	-3	neutral	0,35	medium_impact	-0,68	medium_impact	0,18	medium_impact	-0,13	0,56	0,8	5,97	9,01	N	0,27	N	0,85	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13546	13546	A	C	MI.21846	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1210	404	T	P	Aca/Cca	-2,81	0	0	possibly_damaging	0,87	neutral	0,19	neutral	3,71	neutral	-1,18	deleterious	-4,55	medium_impact	2,25	neutral	0,67	neutral	0,41	deleterious	2,18	17,41	0,21	0,45	disease	0,78	disease	0,87	disease	0,72	disease	0,78	6	neutral	0,92	neutral	0,16	NA	0	deleterious	0,74	low_impact	-1,53	medium_impact	-0,12	medium_impact	0,85	0,55	0,8	5,97	9,01	N	0,28	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13547	13547	C	A	MI.21847	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1211	404	T	K	aCa/aAa	-0,52	0	0	possibly_damaging	0,52	neutral	0,28	neutral	3,72	neutral	-1,01	deleterious	-4,5	medium_impact	2,65	neutral	0,72	neutral	0,43	neutral	1,7	14,43	0,32	0,5	disease	0,85	disease	0,79	disease	0,72	disease	0,8	6	neutral	0,7	neutral	0,38	NA	0	deleterious	0,55	medium_impact	-0,78	medium_impact	0,01	medium_impact	1,22	0,62	0,8	5,97	9,01	N	0,28	N	1	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13547	13547	C	T	MI.21848	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1211	404	T	M	aCa/aTa	-0,52	0	0	benign	0,14	neutral	0,23	neutral	3,71	neutral	-2,57	deleterious	-3,72	low_impact	1	neutral	0,77	neutral	0,74	neutral	0,99	10,62	0,54	0,6	disease	0,63	disease	0,57	neutral	0,45	disease	0,53	1	neutral	0,73	deleterious	0,55	neutral	-6	neutral	0,19	medium_impact	0	medium_impact	-0,06	medium_impact	-0,29	0,64	0,8	5,97	9,01	N	0,34	N	0,93	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13549	13549	A	C	MI.21849	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1213	405	N	H	Aac/Cac	-1,67	0	0	probably_damaging	1	neutral	0,53	neutral	3,56	neutral	-1,8	deleterious	-4,49	high_impact	3,7	neutral	0,62	damaging	0,11	deleterious	3,18	22,7	0,53	0,6	disease	0,82	disease	0,8	disease	0,82	disease	0,83	7	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,26	high_impact	2,18	0,38	0,8	28,52	7,15	N	0,34	N	0,97	polymorphism	0,96	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6052	6052	A	C	MI.2185	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	149	50	N	T	aAc/aCc	5,22	1	0	benign	0,09	deleterious	0	neutral	2,88	neutral	-0,26	neutral	-1,65	medium_impact	2,68	damaging	0,57	neutral	0,67	neutral	1,54	13,55	0,72	0,75	neutral	0,17	disease	0,8	disease	0,6	disease	0,75	5	deleterious	1	neutral	0,46	deleterious	1	neutral	0,21	medium_impact	0,19	low_impact	-1,48	medium_impact	1,38	0,46	0,9	12,87	67,9	P	0,52	P	0,24	disease_causing	0,53	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13549	13549	A	T	MI.21850	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1213	405	N	Y	Aac/Tac	-1,67	0	0	probably_damaging	1	neutral	1	neutral	3,54	neutral	-2,17	deleterious	-7,18	high_impact	4,19	neutral	0,62	damaging	0,11	deleterious	3,84	23,4	0,39	0,5	disease	0,58	disease	0,88	disease	0,77	disease	0,8	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,83	low_impact	-3,6	high_impact	1,89	high_impact	2,62	0,29	0,8	28,52	7,15	N	0,32	N	0,99	polymorphism	0,85	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13549	13549	A	G	MI.21851	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1213	405	N	D	Aac/Gac	-1,67	0	0	probably_damaging	1	neutral	0,21	neutral	3,57	neutral	-1,62	deleterious	-4,49	high_impact	3,77	damaging	0,6	damaging	0,13	deleterious	3,97	23,6	0,58	0,65	disease	0,76	disease	0,79	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,09	high_impact	2,24	0,4	0,8	28,52	7,15	N	0,32	N	0,93	polymorphism	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13550	13550	A	C	MI.21852	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1214	405	N	T	aAc/aCc	8,42	1	0	probably_damaging	1	neutral	0,42	neutral	3,58	neutral	-1,6	deleterious	-5,39	high_impact	3,64	neutral	0,63	damaging	0,11	deleterious	3,44	23	0,49	0,55	disease	0,53	disease	0,81	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,16	high_impact	2,12	0,39	0,8	28,52	7,15	P	0,53	P	0,94	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13550	13550	A	G	MI.21853	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1214	405	N	S	aAc/aGc	8,42	1	0	probably_damaging	1	neutral	0,47	neutral	3,64	neutral	-0,79	deleterious	-4,49	medium_impact	2,73	neutral	0,64	damaging	0,14	deleterious	3,13	22,6	0,52	0,6	disease	0,67	disease	0,78	disease	0,66	disease	0,55	1	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,2	medium_impact	1,29	0,22	0,8	28,52	7,15	N	0,48	N	0,76	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13550	13550	A	T	MI.21854	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1214	405	N	I	aAc/aTc	8,42	1	0	probably_damaging	1	neutral	0,41	neutral	3,56	neutral	-1,79	deleterious	-8,08	high_impact	4,19	neutral	0,63	damaging	0,16	deleterious	3,94	23,5	0,34	0,5	neutral	0,49	disease	0,91	disease	0,73	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,15	high_impact	2,62	0,17	0,8	28,52	7,15	P	0,59	P	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13551	13551	C	A	MI.21855	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1215	405	N	K	aaC/aaA	8,42	1	0	probably_damaging	1	neutral	0,31	neutral	3,59	neutral	-1,36	deleterious	-5,38	high_impact	3,7	damaging	0,58	damaging	0,13	deleterious	4,58	24,4	0,57	0,65	disease	0,77	disease	0,85	disease	0,8	disease	0,8	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,04	high_impact	2,18	0,41	0,8	28,52	7,15	P	0,58	P	1	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13551	13551	C	G	MI.21856	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1215	405	N	K	aaC/aaG	8,42	1	0	probably_damaging	1	neutral	0,31	neutral	3,59	neutral	-1,36	deleterious	-5,38	high_impact	3,7	damaging	0,58	damaging	0,13	deleterious	4,1	23,7	0,57	0,65	disease	0,77	disease	0,85	disease	0,8	disease	0,8	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,04	high_impact	2,18	0,41	0,8	28,52	7,15	P	0,58	P	1	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13552	13552	G	T	MI.21857	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1216	406	A	S	Gcc/Tcc	0,63	0,99	0	possibly_damaging	0,6	neutral	0,41	neutral	3,7	neutral	-1,32	deleterious	-2,55	neutral_impact	0,4	neutral	0,79	neutral	0,71	neutral	0,89	10,04	0,47	0,55	disease	0,5	disease	0,59	neutral	0,31	neutral	0,45	1	neutral	0,63	neutral	0,41	neutral	-3	deleterious	0,45	medium_impact	-0,91	medium_impact	0,15	medium_impact	-0,84	0,84	0,9	16,25	15,48	N	0,33	N	0,32	disease_causing	0,64	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13552	13552	G	C	MI.21858	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1216	406	A	P	Gcc/Ccc	0,63	0,99	0	probably_damaging	0,94	neutral	0,21	neutral	3,68	neutral	-1,48	deleterious	-4,36	medium_impact	2,37	neutral	0,63	neutral	0,33	deleterious	3,74	23,3	0,2	0,45	disease	0,78	disease	0,92	disease	0,77	disease	0,82	6	neutral	0,96	neutral	0,14	deleterious	1	deleterious	0,8	low_impact	-1,88	medium_impact	-0,09	medium_impact	0,96	0,85	0,9	16,25	15,48	N	0,38	N	0,92	disease_causing	0,93	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13552	13552	G	A	MI.21859	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1216	406	A	T	Gcc/Acc	0,63	0,99	0	benign	0,11	neutral	0,4	neutral	3,7	neutral	-1,38	deleterious	-3,29	low_impact	1,42	neutral	0,83	neutral	0,9	neutral	1,43	12,95	0,46	0,55	disease	0,54	disease	0,6	neutral	0,32	neutral	0,48	0	neutral	0,54	deleterious	0,65	neutral	-6	neutral	0,21	medium_impact	0,12	medium_impact	0,14	medium_impact	0,09	0,73	0,85	16,25	15,48	N	0,41	N	0,32	disease_causing	0,8	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6053	6053	C	A	MI.2186	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	150	50	N	K	aaC/aaA	5,91	1	0	benign	0,09	deleterious	0	neutral	2,86	neutral	0,51	neutral	-1,68	high_impact	3,54	damaging	0,59	neutral	0,5	deleterious	2,57	19,94	0,81	0,85	neutral	0,27	disease	0,86	disease	0,64	disease	0,78	6	deleterious	1	neutral	0,46	deleterious	2	neutral	0,27	medium_impact	0,19	low_impact	-1,48	high_impact	2,17	0,58	0,9	12,87	67,9	P	0,54	P	0,52	disease_causing	0,82	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13553	13553	C	T	MI.21860	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1217	406	A	V	gCc/gTc	0,86	1	0	possibly_damaging	0,6	neutral	0,5	neutral	3,72	neutral	-0,74	deleterious	-3,46	medium_impact	2,13	neutral	0,76	neutral	0,55	deleterious	2,88	21,7	0,31	0,45	disease	0,84	disease	0,78	disease	0,66	disease	0,72	4	neutral	0,58	neutral	0,45	NA	0	deleterious	0,56	medium_impact	-0,91	medium_impact	0,23	medium_impact	0,74	0,82	0,85	16,25	15,48	N	0,37	N	0,54	disease_causing	0,9	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13553	13553	C	A	MI.21861	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1217	406	A	D	gCc/gAc	0,86	1	0	probably_damaging	0,92	neutral	0,21	neutral	3,6	deleterious	-3,87	deleterious	-5,22	medium_impact	3,02	neutral	0,68	neutral	0,37	deleterious	4,41	24,1	0,25	0,45	disease	0,57	disease	0,92	disease	0,78	disease	0,83	6	neutral	0,95	neutral	0,15	deleterious	1	deleterious	0,72	low_impact	-1,75	medium_impact	-0,09	medium_impact	1,56	0,57	0,8	16,25	15,48	N	0,4	N	0,98	disease_causing	0,97	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13553	13553	C	G	MI.21862	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1217	406	A	G	gCc/gGc	0,86	1	0	possibly_damaging	0,68	neutral	0,33	neutral	3,68	neutral	-0,88	deleterious	-3,52	medium_impact	2,02	neutral	0,78	neutral	0,61	deleterious	2,41	18,9	0,3	0,45	disease	0,67	disease	0,77	disease	0,64	disease	0,59	2	neutral	0,74	neutral	0,33	NA	0	deleterious	0,53	low_impact	-1,06	medium_impact	0,06	medium_impact	0,64	0,71	0,85	16,25	15,48	N	0,33	N	0,6	disease_causing	0,87	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13555	13555	T	C	MI.21863	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1219	407	W	R	Tga/Cga	2	1	0	probably_damaging	1	neutral	0,34	neutral	3,5	deleterious	-4,82	deleterious	-12,59	medium_impact	3,5	neutral	0,7	damaging	0,1	deleterious	3,63	23,2	0,28	0,45	disease	0,59	disease	0,92	disease	0,86	disease	0,86	7	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,07	medium_impact	1,99	0,38	0,8	27,86	7,14	N	0,45	N	0,97	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13555	13555	T	G	MI.21864	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1219	407	W	G	Tga/Gga	2	1	0	probably_damaging	1	neutral	0,36	neutral	3,53	neutral	-2,67	deleterious	-11,69	medium_impact	3,08	neutral	0,74	damaging	0,17	deleterious	4	23,6	0,26	0,45	disease	0,64	disease	0,88	disease	0,82	disease	0,78	6	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,1	medium_impact	1,61	0,37	0,8	27,86	7,14	N	0,41	N	0,98	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13556	13556	G	C	MI.21865	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1220	407	W	S	tGa/tCa	4,52	1	0	probably_damaging	1	neutral	0,52	neutral	3,51	deleterious	-3,86	deleterious	-12,59	medium_impact	2,85	neutral	0,79	damaging	0,13	deleterious	4,11	23,7	0,24	0,45	disease	0,56	disease	0,9	disease	0,81	disease	0,78	6	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,25	medium_impact	1,4	0,28	0,8	27,86	7,14	N	0,4	N	0,96	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13556	13556	G	T	MI.21866	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1220	407	W	L	tGa/tTa	4,52	1	0	probably_damaging	1	neutral	0,75	neutral	3,66	neutral	-1,64	deleterious	-11,69	low_impact	1,12	neutral	0,75	damaging	0,23	deleterious	4,38	24,1	0,26	0,45	disease	0,55	disease	0,85	disease	0,79	disease	0,64	3	deleterious	1	neutral	0,38	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,5	medium_impact	-0,18	0,33	0,8	27,86	7,14	N	0,38	N	0,97	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13557	13557	A	T	MI.21867	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1221	407	W	C	tgA/tgT	7,04	1	0	probably_damaging	1	neutral	0,19	neutral	3,49	deleterious	-5,51	deleterious	-11,69	medium_impact	2,73	neutral	0,73	damaging	0,15	deleterious	4,23	23,9	0,24	0,45	disease	0,69	disease	0,9	disease	0,8	disease	0,66	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,12	medium_impact	1,29	0,33	0,8	27,86	7,14	N	0,42	N	0,98	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13557	13557	A	C	MI.21868	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1221	407	W	C	tgA/tgC	7,04	1	0	probably_damaging	1	neutral	0,19	neutral	3,49	deleterious	-5,51	deleterious	-11,69	medium_impact	2,73	neutral	0,73	damaging	0,15	deleterious	4,13	23,8	0,24	0,45	disease	0,69	disease	0,9	disease	0,8	disease	0,66	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,12	medium_impact	1,29	0,33	0,8	27,86	7,14	N	0,41	N	0,98	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13558	13558	G	T	MI.21869	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1222	408	A	S	Gcc/Tcc	2	1	0	probably_damaging	1	neutral	0,52	neutral	3,52	neutral	-2,39	deleterious	-2,7	low_impact	1,81	damaging	0,49	damaging	0,08	deleterious	3,84	23,4	0,31	0,5	neutral	0,38	disease	0,8	disease	0,58	disease	0,53	1	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,25	medium_impact	0,45	0,84	0,9	27,03	7,15	N	0,37	N	0,97	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6053	6053	C	G	MI.2187	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	150	50	N	K	aaC/aaG	5,91	1	0	benign	0,09	deleterious	0	neutral	2,86	neutral	0,51	neutral	-1,68	high_impact	3,54	damaging	0,59	neutral	0,5	deleterious	2,11	16,91	0,81	0,85	neutral	0,27	disease	0,86	disease	0,64	disease	0,78	6	deleterious	1	neutral	0,46	deleterious	2	neutral	0,27	medium_impact	0,19	low_impact	-1,48	high_impact	2,17	0,58	0,9	12,87	67,9	P	0,54	P	0,52	disease_causing	0,82	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13558	13558	G	A	MI.21870	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1222	408	A	T	Gcc/Acc	2	1	0	probably_damaging	1	neutral	0,44	neutral	3,53	neutral	-2,36	deleterious	-3,6	medium_impact	2,92	damaging	0,46	damaging	0,07	deleterious	4,3	24	0,43	0,55	disease	0,69	disease	0,83	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,18	medium_impact	1,46	0,76	0,85	27,03	7,15	N	0,46	N	0,94	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13558	13558	G	C	MI.21871	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1222	408	A	P	Gcc/Ccc	2	1	0	probably_damaging	1	neutral	0,19	neutral	3,49	neutral	-2,52	deleterious	-4,5	medium_impact	3,27	damaging	0,53	damaging	0,05	deleterious	3,95	23,6	0,11	0,4	disease	0,73	disease	0,91	disease	0,78	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,88	low_impact	-3,6	medium_impact	-0,12	medium_impact	1,78	0,86	0,9	27,03	7,15	N	0,45	N	0,96	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13559	13559	C	G	MI.21872	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1223	408	A	G	gCc/gGc	9,11	1	0	probably_damaging	1	neutral	0,31	neutral	3,52	neutral	-1,89	deleterious	-3,6	medium_impact	2,73	damaging	0,49	damaging	0,1	deleterious	4,07	23,7	0,18	0,45	neutral	0,39	disease	0,78	disease	0,67	disease	0,55	1	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,04	medium_impact	1,29	0,8	0,85	27,03	7,15	P	0,5	N	0,84	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13559	13559	C	A	MI.21873	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1223	408	A	D	gCc/gAc	9,11	1	0	probably_damaging	1	neutral	0,23	neutral	3,44	deleterious	-5,7	deleterious	-5,4	high_impact	4,37	damaging	0,56	damaging	0,03	deleterious	4,72	24,6	0,11	0,4	disease	0,7	disease	0,93	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,06	high_impact	2,79	0,75	0,85	27,03	7,15	P	0,59	P	0,95	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13559	13559	C	T	MI.21874	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1223	408	A	V	gCc/gTc	9,11	1	0	probably_damaging	1	neutral	0,51	neutral	3,59	neutral	-0,92	deleterious	-3,6	medium_impact	2,29	damaging	0,48	damaging	0,06	deleterious	4,54	24,3	0,38	0,5	disease	0,83	disease	0,82	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,24	medium_impact	0,89	0,75	0,85	27,03	7,15	P	0,54	P	0,79	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13561	13561	C	A	MI.21875	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1225	409	L	M	Cta/Ata	1,08	1	0	probably_damaging	1	neutral	0,24	neutral	3,46	neutral	-2,87	neutral	-1,8	medium_impact	2,87	neutral	0,71	damaging	0,17	deleterious	3,85	23,4	0,25	0,45	disease	0,66	disease	0,55	disease	0,52	neutral	0,49	0	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,71	low_impact	-3,6	medium_impact	-0,04	medium_impact	1,42	0,7	0,85	10,95	7,18	N	0,38	N	0,85	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13561	13561	C	G	MI.21876	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1225	409	L	V	Cta/Gta	1,08	1	0	probably_damaging	1	neutral	0,51	neutral	3,56	neutral	-1,47	deleterious	-2,7	medium_impact	2,77	neutral	0,7	damaging	0,15	deleterious	3,5	23,1	0,23	0,45	disease	0,74	disease	0,54	disease	0,53	disease	0,51	0	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,24	medium_impact	1,33	0,6	0,8	10,95	7,18	N	0,32	N	0,78	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13562	13562	T	A	MI.21877	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1226	409	L	Q	cTa/cAa	3,38	1	0	probably_damaging	1	neutral	0,29	neutral	3,42	deleterious	-5,11	deleterious	-5,39	high_impact	4,34	neutral	0,67	damaging	0,12	deleterious	4,16	23,8	0,14	0,4	disease	0,56	disease	0,81	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,02	high_impact	2,76	0,62	0,8	10,95	7,18	N	0,47	N	0,98	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13562	13562	T	C	MI.21878	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1226	409	L	P	cTa/cCa	3,38	1	0	probably_damaging	1	neutral	0,21	neutral	3,43	deleterious	-4,09	deleterious	-6,29	high_impact	4	neutral	0,62	damaging	0,12	deleterious	4,01	23,6	0,13	0,4	neutral	0,4	disease	0,84	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	-0,09	high_impact	2,45	0,59	0,8	10,95	7,18	N	0,44	N	0,99	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13562	13562	T	G	MI.21879	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1226	409	L	R	cTa/cGa	3,38	1	0	probably_damaging	1	neutral	0,34	neutral	3,42	deleterious	-4,61	deleterious	-5,39	high_impact	4,34	neutral	0,62	damaging	0,12	deleterious	4,29	24	0,12	0,4	disease	0,69	disease	0,87	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,07	high_impact	2,76	0,68	0,85	10,95	7,18	N	0,51	P	1	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6054	6054	G	C	MI.2188	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	151	51	D	H	Gac/Cac	-3,34	0	0	probably_damaging	1	deleterious	0,04	neutral	2,66	deleterious	-3,98	deleterious	-4,22	medium_impact	3	damaging	0,55	neutral	0,3	deleterious	3,44	23	0,46	0,55	neutral	0,4	disease	0,87	neutral	0,4	disease	0,53	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,82	low_impact	-3,58	medium_impact	-0,58	medium_impact	1,67	0,46	0,9	3,7	7,26	N	0,34	N	0,97	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13564	13564	T	A	MI.21880	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1228	410	S	T	Tct/Act	-8,77	0	0	benign	0,02	neutral	0,26	neutral	3,83	neutral	0,17	neutral	0,8	neutral_impact	-0,99	neutral	0,84	neutral	0,97	deleterious	2	16,24	0,22	0,45	disease	0,51	neutral	0,07	neutral	0,22	neutral	0,24	5	neutral	0,73	deleterious	0,62	neutral	-6	deleterious	0,62	medium_impact	0,86	medium_impact	-0,02	low_impact	-2,11	0,8	0,85	25,04	21	N	0,48	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13564	13564	T	C	MI.21881	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1228	410	S	P	Tct/Cct	-8,77	0	0	possibly_damaging	0,61	neutral	0,12	neutral	3,76	neutral	-0,59	neutral	-1,52	low_impact	1,7	damaging	0,59	neutral	0,41	deleterious	3,95	23,6	0,13	0,4	disease	0,6	disease	0,75	disease	0,54	disease	0,69	4	neutral	0,88	neutral	0,26	neutral	-3	deleterious	0,78	medium_impact	-0,93	medium_impact	-0,25	medium_impact	0,35	0,61	0,8	25,04	21	N	0,28	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13564	13564	T	G	MI.21882	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1228	410	S	A	Tct/Gct	-8,77	0	0	benign	0,17	neutral	0,41	neutral	3,96	neutral	1,92	neutral	0,08	neutral_impact	-0,34	neutral	0,79	neutral	0,82	deleterious	2,48	19,35	0,26	0,45	neutral	0,44	neutral	0,11	neutral	0,26	neutral	0,32	4	neutral	0,51	deleterious	0,62	neutral	-6	deleterious	0,61	medium_impact	-0,09	medium_impact	0,15	low_impact	-1,51	0,71	0,85	25,04	21	N	0,42	N	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13565	13565	C	G	MI.21883	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1229	410	S	C	tCt/tGt	-14,96	0	0	benign	0,02	neutral	0,12	neutral	3,73	neutral	-2,38	neutral	-0,34	neutral_impact	0,73	neutral	0,84	neutral	0,79	deleterious	2,51	19,56	0,15	0,4	disease	0,76	disease	0,52	neutral	0,29	neutral	0,5	0	neutral	0,88	deleterious	0,55	neutral	-6	deleterious	0,72	medium_impact	0,86	medium_impact	-0,25	medium_impact	-0,54	0,68	0,85	25,04	21	N	0,36	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13565	13565	C	A	MI.21884	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1229	410	S	Y	tCt/tAt	-14,96	0	0	benign	0,37	neutral	0,53	neutral	3,75	neutral	-0,85	neutral	-0,62	neutral_impact	0,76	neutral	0,82	neutral	0,6	deleterious	2,93	22	0,19	0,45	neutral	0,32	neutral	0,47	neutral	0,43	neutral	0,5	0	neutral	0,4	deleterious	0,58	neutral	-6	deleterious	0,65	medium_impact	-0,53	medium_impact	0,26	medium_impact	-0,51	0,68	0,85	25,04	21	N	0,27	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13565	13565	C	T	MI.21885	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1229	410	S	F	tCt/tTt	-14,96	0	0	benign	0,01	neutral	0,46	neutral	3,81	neutral	-0,08	neutral	0	neutral_impact	-0,35	neutral	0,89	neutral	0,94	deleterious	2,86	21,7	0,21	0,45	neutral	0,33	disease	0,52	neutral	0,35	neutral	0,44	1	neutral	0,53	deleterious	0,73	neutral	-6	deleterious	0,66	medium_impact	1,15	medium_impact	0,19	low_impact	-1,52	0,46	0,8	25,04	21	N	0,31	N	0,08	polymorphism	1	0,01	rs56039545	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13567	13567	A	G	MI.21886	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1231	411	I	V	Att/Gtt	-3,5	0	0	benign	0	neutral	0,53	neutral	3,69	neutral	-0,1	neutral	-0,54	low_impact	1,23	neutral	0,87	neutral	0,93	neutral	1,15	11,5	0,45	0,55	neutral	0,46	neutral	0,22	neutral	0,36	neutral	0,42	2	neutral	0,46	deleterious	0,77	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	0,26	medium_impact	-0,08	0,5	0,8	13,43	12,4	N	0,33	N	0,64	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13567	13567	A	C	MI.21887	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1231	411	I	L	Att/Ctt	-3,5	0	0	benign	0,01	neutral	0,76	neutral	3,9	neutral	0,17	neutral	-0,82	neutral_impact	-0,39	neutral	0,8	neutral	0,93	neutral	-0,75	0,06	0,28	0,45	neutral	0,38	neutral	0,11	neutral	0,2	neutral	0,28	4	neutral	0,22	deleterious	0,88	neutral	-6	neutral	0,11	medium_impact	1,15	medium_impact	0,51	low_impact	-1,56	0,6	0,8	13,43	12,4	N	0,32	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13567	13567	A	T	MI.21888	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1231	411	I	F	Att/Ttt	-3,5	0	0	benign	0,14	neutral	0,72	neutral	3,55	neutral	-2,06	deleterious	-2,81	low_impact	1,68	neutral	0,71	neutral	0,73	deleterious	2,24	17,77	0,3	0,45	disease	0,72	disease	0,66	neutral	0,5	disease	0,53	1	neutral	0,16	deleterious	0,79	neutral	-6	neutral	0,35	medium_impact	0	medium_impact	0,46	medium_impact	0,33	0,7	0,85	13,43	12,4	N	0,24	N	0,59	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13568	13568	T	G	MI.21889	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1232	411	I	S	aTt/aGt	-0,29	0	0	benign	0	neutral	0,46	neutral	3,51	deleterious	-3,27	deleterious	-4,04	medium_impact	2,42	neutral	0,74	neutral	0,62	deleterious	2,45	19,17	0,24	0,45	disease	0,82	disease	0,66	disease	0,58	disease	0,69	4	neutral	0,53	deleterious	0,73	neutral	-3	neutral	0,31	high_impact	2,1	medium_impact	0,19	medium_impact	1,01	0,42	0,8	13,43	12,4	N	0,29	N	0,88	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6054	6054	G	T	MI.2189	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	151	51	D	Y	Gac/Tac	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-5	deleterious	-5,46	medium_impact	3,29	damaging	0,42	neutral	0,3	deleterious	3,76	23,3	0,32	0,55	disease	0,61	disease	0,95	neutral	0,44	disease	0,56	1	deleterious	1	neutral	0	deleterious	5	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	medium_impact	1,94	0,19	0,9	3,7	7,26	N	0,4	N	0,94	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13568	13568	T	A	MI.21890	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1232	411	I	N	aTt/aAt	-0,29	0	0	benign	0,14	neutral	0,39	neutral	3,48	deleterious	-4,99	deleterious	-4,93	medium_impact	2,83	neutral	0,68	neutral	0,41	deleterious	2,71	20,8	0,22	0,45	disease	0,92	disease	0,76	disease	0,6	disease	0,82	6	neutral	0,54	deleterious	0,63	neutral	-3	deleterious	0,53	medium_impact	0	medium_impact	0,13	medium_impact	1,38	0,6	0,8	13,43	12,4	N	0,26	N	0,91	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13568	13568	T	C	MI.21891	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1232	411	I	T	aTt/aCt	-0,29	0	0	benign	0	neutral	0,44	neutral	3,52	neutral	-2,82	deleterious	-2,9	low_impact	0,88	neutral	0,9	neutral	0,97	deleterious	0,18	4,43	0,4	0,5	disease	0,81	neutral	0,33	neutral	0,39	disease	0,65	3	neutral	0,56	deleterious	0,72	neutral	-6	neutral	0,23	high_impact	2,1	medium_impact	0,18	medium_impact	-0,4	0,48	0,8	13,43	12,4	N	0,36	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13569	13569	T	G	MI.21892	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1233	411	I	M	atT/atG	2,92	0,13	0	benign	0,01	neutral	0,26	neutral	3,57	neutral	-2,3	neutral	-1,39	neutral_impact	0,13	neutral	0,87	neutral	0,94	deleterious	0,11	3,74	0,33	0,5	disease	0,67	neutral	0,24	neutral	0,29	disease	0,56	1	neutral	0,73	deleterious	0,63	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	-0,02	low_impact	-1,08	0,71	0,85	13,43	12,4	N	0,44	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13569	13569	T	A	MI.21893	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1233	411	I	M	atT/atA	2,92	0,13	0	benign	0,01	neutral	0,26	neutral	3,57	neutral	-2,3	neutral	-1,39	neutral_impact	0,13	neutral	0,87	neutral	0,94	deleterious	0,41	6,66	0,33	0,5	disease	0,67	neutral	0,24	neutral	0,29	disease	0,56	1	neutral	0,73	deleterious	0,63	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	-0,02	low_impact	-1,08	0,71	0,85	13,43	12,4	N	0,44	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13570	13570	A	G	MI.21894	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1234	412	T	A	Act/Gct	-9,46	0	0	benign	0,42	neutral	0,65	neutral	3,88	neutral	1,35	deleterious	-4,49	medium_impact	2,24	neutral	0,65	neutral	0,53	neutral	1,79	14,95	0,42	0,5	neutral	0,34	neutral	0,49	disease	0,66	neutral	0,46	1	neutral	0,35	deleterious	0,62	neutral	-3	neutral	0,34	medium_impact	-0,61	medium_impact	0,38	medium_impact	0,84	0,51	0,8	19,73	7,34	N	0,35	N	0,67	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13570	13570	A	T	MI.21895	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1234	412	T	S	Act/Tct	-9,46	0	0	possibly_damaging	0,66	neutral	0,49	neutral	3,66	neutral	-1,34	deleterious	-3,59	medium_impact	2,92	neutral	0,7	neutral	0,5	neutral	1,74	14,63	0,3	0,45	disease	0,78	disease	0,68	disease	0,63	disease	0,62	2	neutral	0,64	neutral	0,42	NA	0	deleterious	0,52	low_impact	-1,02	medium_impact	0,22	medium_impact	1,46	0,68	0,85	19,73	7,34	N	0,26	N	0,85	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13570	13570	A	C	MI.21896	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1234	412	T	P	Act/Cct	-9,46	0	0	probably_damaging	0,92	neutral	0,21	neutral	3,62	neutral	-2,32	deleterious	-5,39	high_impact	4,28	neutral	0,66	neutral	0,38	deleterious	3,38	23	0,11	0,4	disease	0,9	disease	0,84	disease	0,78	disease	0,85	7	neutral	0,95	neutral	0,15	deleterious	2	deleterious	0,77	low_impact	-1,75	medium_impact	-0,09	high_impact	2,71	0,52	0,8	19,73	7,34	N	0,47	N	0,97	polymorphism	0,98	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13571	13571	C	A	MI.21897	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1235	412	T	N	aCt/aAt	6,81	1	0	probably_damaging	0,92	neutral	0,34	neutral	3,61	deleterious	-3,5	deleterious	-4,49	high_impact	4,28	neutral	0,65	neutral	0,45	deleterious	3,49	23,1	0,39	0,5	disease	0,88	disease	0,82	disease	0,6	disease	0,75	5	neutral	0,93	neutral	0,21	deleterious	2	deleterious	0,73	low_impact	-1,75	medium_impact	0,07	high_impact	2,71	0,77	0,85	19,73	7,34	P	0,59	P	0,93	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13571	13571	C	G	MI.21898	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1235	412	T	S	aCt/aGt	6,81	1	0	possibly_damaging	0,66	neutral	0,49	neutral	3,66	neutral	-1,34	deleterious	-3,59	medium_impact	2,92	neutral	0,7	neutral	0,5	deleterious	1,94	15,83	0,3	0,45	disease	0,78	disease	0,68	disease	0,63	disease	0,62	2	neutral	0,64	neutral	0,42	NA	0	deleterious	0,52	low_impact	-1,02	medium_impact	0,22	medium_impact	1,46	0,68	0,85	19,73	7,34	P	0,55	P	0,85	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13571	13571	C	T	MI.21899	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1235	412	T	I	aCt/aTt	6,81	1	0	benign	0,05	neutral	0,44	neutral	3,72	neutral	-0,1	deleterious	-5,39	medium_impact	2,56	neutral	0,66	neutral	0,56	deleterious	2,06	16,62	0,24	0,45	disease	0,63	disease	0,82	disease	0,59	disease	0,65	3	neutral	0,52	deleterious	0,7	neutral	-3	neutral	0,25	medium_impact	0,47	medium_impact	0,18	medium_impact	1,14	0,58	0,8	19,73	7,34	N	0,51	P	0,92	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8629	8629	A	C	MI.219	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	103	35	K	Q	Aaa/Caa	-14,22	0	0	possibly_damaging	0,56	neutral	0,27	neutral	4,36	neutral	-0,83	neutral	-1,1	neutral_impact	0,7	neutral	0,85	neutral	0,7	neutral	1,64	14,07	0,6	0,7	disease	0,55	neutral	0,25	neutral	0,28	disease	0,53	1	neutral	0,73	neutral	0,36	neutral	-3	deleterious	0,5	medium_impact	-0,86	medium_impact	0,05	medium_impact	-0,5	0,57	0,9	20,35	18,29	N	0,41	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6054	6054	G	A	MI.2190	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	151	51	D	N	Gac/Aac	-3,34	0	0	probably_damaging	1	deleterious	0,03	neutral	2,7	neutral	-2,42	deleterious	-2,96	medium_impact	2,04	damaging	0,42	neutral	0,42	deleterious	4,13	23,8	0,83	0,85	neutral	0,21	disease	0,85	neutral	0,3	disease	0,52	0	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,78	low_impact	-3,58	medium_impact	-0,65	medium_impact	0,79	0,68	0,9	3,7	7,26	N	0,45	N	0,89	disease_causing	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13573	13573	C	A	MI.21900	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1237	413	L	I	Ctc/Atc	-9	0	0	possibly_damaging	0,69	neutral	0,48	neutral	3,53	neutral	-1,81	neutral	-1,75	medium_impact	2,2	neutral	0,74	neutral	0,61	deleterious	4,14	23,8	0,29	0,45	disease	0,6	neutral	0,43	neutral	0,32	disease	0,59	2	neutral	0,67	neutral	0,4	NA	0	deleterious	0,71	low_impact	-1,08	medium_impact	0,21	medium_impact	0,81	0,66	0,8	2,16	9,23	N	0,32	N	0,83	polymorphism	1	0,02	rs28462226	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13573	13573	C	G	MI.21901	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1237	413	L	V	Ctc/Gtc	-9	0	0	possibly_damaging	0,69	neutral	0,58	neutral	3,57	neutral	-1,11	deleterious	-2,61	medium_impact	2,44	neutral	0,76	neutral	0,57	deleterious	3,53	23,1	0,24	0,45	disease	0,51	neutral	0,34	neutral	0,5	neutral	0,34	3	neutral	0,64	neutral	0,45	NA	0	deleterious	0,68	low_impact	-1,08	medium_impact	0,31	medium_impact	1,03	0,57	0,8	2,16	9,23	N	0,27	N	0,78	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13573	13573	C	T	MI.21902	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1237	413	L	F	Ctc/Ttc	-9	0	0	benign	0,14	neutral	0,75	neutral	3,48	neutral	-2,76	deleterious	-3,44	medium_impact	2,07	neutral	0,75	neutral	0,46	deleterious	4,03	23,6	0,31	0,45	disease	0,82	disease	0,64	disease	0,52	disease	0,6	2	neutral	0,14	deleterious	0,81	neutral	-3	deleterious	0,77	medium_impact	0	medium_impact	0,5	medium_impact	0,69	0,6	0,8	2,16	9,23	N	0,18	N	0,98	polymorphism	0,99	0,06	rs28462226	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13574	13574	T	A	MI.21903	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1238	413	L	H	cTc/cAc	-0,06	0	0	probably_damaging	0,98	neutral	0,53	neutral	3,39	deleterious	-5,89	deleterious	-6,14	high_impact	4,37	neutral	0,7	neutral	0,34	deleterious	4,16	23,8	0,13	0,4	disease	0,94	disease	0,71	disease	0,69	disease	0,81	6	neutral	0,98	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-2,35	medium_impact	0,26	high_impact	2,79	0,61	0,8	2,16	9,23	N	0,35	N	0,97	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13574	13574	T	G	MI.21904	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1238	413	L	R	cTc/cGc	-0,06	0	0	probably_damaging	0,97	neutral	0,34	neutral	3,39	deleterious	-5,38	deleterious	-5,27	high_impact	4,37	neutral	0,63	neutral	0,3	deleterious	4,27	24	0,11	0,4	disease	0,92	disease	0,82	disease	0,72	disease	0,82	6	neutral	0,97	neutral	0,19	deleterious	2	deleterious	0,87	low_impact	-2,18	medium_impact	0,07	high_impact	2,79	0,5	0,8	2,16	9,23	N	0,4	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13574	13574	T	C	MI.21905	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1238	413	L	P	cTc/cCc	-0,06	0	0	probably_damaging	0,98	neutral	0,22	neutral	3,39	deleterious	-5,85	deleterious	-6,17	high_impact	4,37	neutral	0,66	neutral	0,32	deleterious	3,99	23,6	0,12	0,4	disease	0,94	disease	0,8	disease	0,73	disease	0,83	7	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-2,35	medium_impact	-0,07	high_impact	2,79	0,6	0,8	2,16	9,23	N	0,39	N	0,99	polymorphism	0,75	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13576	13576	A	G	MI.21906	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1240	414	I	V	Atc/Gtc	-9,69	0	0	benign	0,01	neutral	0,53	neutral	3,73	neutral	-0,13	neutral	-0,49	neutral_impact	0,36	neutral	0,87	neutral	0,98	neutral	1,74	14,63	0,53	0,6	neutral	0,44	neutral	0,15	neutral	0,37	neutral	0,31	4	neutral	0,46	deleterious	0,76	neutral	-6	deleterious	0,54	medium_impact	1,15	medium_impact	0,26	medium_impact	-0,87	0,38	0,8	7,3	10,37	N	0,37	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13576	13576	A	C	MI.21907	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1240	414	I	L	Atc/Ctc	-9,69	0	0	benign	0,01	neutral	0,84	neutral	3,85	neutral	0,26	neutral	-1,27	low_impact	1,23	neutral	0,79	neutral	0,9	deleterious	2,35	18,52	0,34	0,5	neutral	0,37	neutral	0,2	neutral	0,28	neutral	0,35	3	neutral	0,13	deleterious	0,92	neutral	-6	deleterious	0,55	medium_impact	1,15	medium_impact	0,63	medium_impact	-0,08	0,49	0,8	7,3	10,37	N	0,34	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13576	13576	A	T	MI.21908	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1240	414	I	F	Atc/Ttc	-9,69	0	0	possibly_damaging	0,45	neutral	0,73	neutral	3,61	neutral	-1,84	deleterious	-3,21	low_impact	1,62	neutral	0,72	neutral	0,73	deleterious	3,88	23,5	0,39	0,5	disease	0,56	disease	0,65	disease	0,52	disease	0,52	0	neutral	0,35	deleterious	0,64	neutral	-3	deleterious	0,71	medium_impact	-0,66	medium_impact	0,47	medium_impact	0,28	0,59	0,8	7,3	10,37	N	0,24	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13577	13577	T	C	MI.21909	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1241	414	I	T	aTc/aCc	-1,67	0	0	benign	0,32	neutral	0,47	neutral	3,53	neutral	-2,64	deleterious	-3,51	low_impact	1,72	neutral	0,86	neutral	0,97	deleterious	3,46	23	0,46	0,55	disease	0,77	neutral	0,47	disease	0,59	disease	0,65	3	neutral	0,44	deleterious	0,58	neutral	-6	deleterious	0,75	medium_impact	-0,44	medium_impact	0,2	medium_impact	0,37	0,38	0,8	7,3	10,37	N	0,37	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6055	6055	A	T	MI.2191	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	152	51	D	V	gAc/gTc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,74	deleterious	-4,15	deleterious	-5,5	high_impact	3,63	damaging	0,49	neutral	0,34	deleterious	4,2	23,9	0,29	0,55	neutral	0,46	disease	0,95	disease	0,61	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,25	0,21	0,9	3,7	7,26	N	0,47	N	0,93	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13577	13577	T	G	MI.21910	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1241	414	I	S	aTc/aGc	-1,67	0	0	possibly_damaging	0,53	neutral	0,51	neutral	3,53	deleterious	-3,29	deleterious	-4,61	medium_impact	2,38	neutral	0,75	neutral	0,47	deleterious	4,4	24,1	0,29	0,45	disease	0,7	disease	0,73	disease	0,61	disease	0,68	4	neutral	0,52	deleterious	0,49	NA	0	deleterious	0,77	medium_impact	-0,8	medium_impact	0,24	medium_impact	0,97	0,38	0,8	7,3	10,37	N	0,24	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13577	13577	T	A	MI.21911	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1241	414	I	N	aTc/aAc	-1,67	0	0	possibly_damaging	0,84	neutral	0,37	neutral	3,48	deleterious	-5,1	deleterious	-5,53	high_impact	3,88	neutral	0,7	neutral	0,41	deleterious	4,59	24,4	0,23	0,45	disease	0,92	disease	0,78	disease	0,63	disease	0,8	6	neutral	0,85	neutral	0,27	deleterious	1	deleterious	0,81	low_impact	-1,43	medium_impact	0,11	high_impact	2,34	0,4	0,8	7,3	10,37	N	0,33	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13578	13578	C	A	MI.21912	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1242	414	I	M	atC/atA	2,46	0,04	0	benign	0,07	neutral	0,27	neutral	3,54	deleterious	-3,03	neutral	-1,98	low_impact	1,49	neutral	0,83	neutral	0,91	deleterious	2,87	21,7	0,38	0,5	disease	0,75	neutral	0,36	neutral	0,36	disease	0,65	3	neutral	0,7	deleterious	0,6	neutral	-6	deleterious	0,71	medium_impact	0,32	medium_impact	-0,01	medium_impact	0,16	0,61	0,8	7,3	10,37	N	0,45	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13578	13578	C	G	MI.21913	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1242	414	I	M	atC/atG	2,46	0,04	0	benign	0,07	neutral	0,27	neutral	3,54	deleterious	-3,03	neutral	-1,98	low_impact	1,49	neutral	0,83	neutral	0,91	deleterious	2,38	18,66	0,38	0,5	disease	0,75	neutral	0,36	neutral	0,36	disease	0,65	3	neutral	0,7	deleterious	0,6	neutral	-6	deleterious	0,71	medium_impact	0,32	medium_impact	-0,01	medium_impact	0,16	0,61	0,8	7,3	10,37	N	0,45	N	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13579	13579	G	A	MI.21914	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1243	415	A	T	Gct/Act	-7,17	0	0	benign	0,16	neutral	0,46	neutral	3,59	neutral	-1,61	deleterious	-3,45	medium_impact	2,18	damaging	0,52	neutral	0,46	deleterious	4,26	23,9	0,43	0,55	neutral	0,38	disease	0,71	disease	0,59	disease	0,61	2	neutral	0,45	deleterious	0,65	neutral	-3	deleterious	0,72	medium_impact	-0,06	medium_impact	0,19	medium_impact	0,79	0,7	0,85	18,24	7,08	N	0,36	N	0,5	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13579	13579	G	C	MI.21915	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1243	415	A	P	Gct/Cct	-7,17	0	0	probably_damaging	0,96	neutral	0,22	neutral	3,47	deleterious	-5,48	deleterious	-4,41	high_impact	4,47	damaging	0,55	neutral	0,38	deleterious	3,89	23,5	0,16	0,45	disease	0,9	disease	0,86	disease	0,79	disease	0,85	7	neutral	0,97	neutral	0,13	deleterious	2	deleterious	0,87	low_impact	-2,06	medium_impact	-0,07	high_impact	2,88	0,76	0,85	18,24	7,08	N	0,53	P	0,93	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13579	13579	G	T	MI.21916	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1243	415	A	S	Gct/Tct	-7,17	0	0	possibly_damaging	0,69	neutral	0,48	neutral	3,67	neutral	-1,87	deleterious	-2,56	low_impact	1,35	neutral	0,61	neutral	0,65	deleterious	3,77	23,4	0,45	0,55	neutral	0,43	disease	0,69	disease	0,58	neutral	0,49	0	neutral	0,67	neutral	0,4	neutral	-3	deleterious	0,75	low_impact	-1,08	medium_impact	0,21	medium_impact	0,03	0,79	0,85	18,24	7,08	N	0,3	N	0,67	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13580	13580	C	T	MI.21917	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1244	415	A	V	gCt/gTt	5,9	1	0	possibly_damaging	0,69	neutral	0,45	neutral	3,56	neutral	-1,54	deleterious	-3,54	medium_impact	3,15	damaging	0,53	neutral	0,4	deleterious	4,51	24,3	0,41	0,5	disease	0,53	disease	0,76	disease	0,66	disease	0,68	4	neutral	0,68	neutral	0,38	NA	0	deleterious	0,75	low_impact	-1,08	medium_impact	0,18	medium_impact	1,67	0,71	0,85	18,24	7,08	P	0,66	P	0,63	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13580	13580	C	G	MI.21918	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1244	415	A	G	gCt/gGt	5,9	1	0	possibly_damaging	0,81	neutral	0,32	neutral	3,7	neutral	-0,41	deleterious	-3,53	medium_impact	2,27	damaging	0,55	neutral	0,5	deleterious	4,08	23,7	0,38	0,5	neutral	0,46	disease	0,76	disease	0,64	disease	0,61	2	neutral	0,84	neutral	0,26	NA	0	deleterious	0,72	low_impact	-1,34	medium_impact	0,05	medium_impact	0,87	0,73	0,85	18,24	7,08	P	0,6	P	0,7	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	C13580G	Thyroid Cancer	-	+	Reported	1
chrM	13580	13580	C	A	MI.21919	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1244	415	A	D	gCt/gAt	5,9	1	0	probably_damaging	0,94	neutral	0,23	neutral	3,46	deleterious	-5,81	deleterious	-5,26	high_impact	4,47	damaging	0,59	neutral	0,41	deleterious	4,55	24,4	0,14	0,4	disease	0,89	disease	0,9	disease	0,78	disease	0,86	7	neutral	0,96	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-1,88	medium_impact	-0,06	high_impact	2,88	0,56	0,8	18,24	7,08	P	0,65	P	0,96	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6055	6055	A	G	MI.2192	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	152	51	D	G	gAc/gGc	6,14	1	0	probably_damaging	1	neutral	0,21	neutral	2,65	deleterious	-3,24	deleterious	-4,25	medium_impact	2,25	damaging	0,46	neutral	0,48	deleterious	4,43	24,2	0,46	0,55	neutral	0,3	disease	0,86	neutral	0,4	disease	0,53	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,77	low_impact	-3,58	medium_impact	-0,13	medium_impact	0,98	0,4	0,9	3,7	7,26	P	0,58	P	0,85	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13582	13582	A	T	MI.21920	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1246	416	T	S	Acc/Tcc	-3,27	0	0	probably_damaging	1	neutral	0,46	neutral	3,7	neutral	0,61	deleterious	-3,53	medium_impact	3,21	neutral	0,6	neutral	0,59	deleterious	3,93	23,5	0,44	0,55	neutral	0,39	disease	0,66	disease	0,64	disease	0,66	3	deleterious	0,99	neutral	0,23	deleterious	1	deleterious	0,71	low_impact	-3,6	medium_impact	0,19	medium_impact	1,73	0,48	0,8	7,3	9,49	N	0,37	N	0,85	disease_causing	0,93	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13582	13582	A	C	MI.21921	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1246	416	T	P	Acc/Ccc	-3,27	0	0	probably_damaging	1	neutral	0,2	neutral	3,49	deleterious	-3,98	deleterious	-5,26	high_impact	4,66	neutral	0,61	neutral	0,41	deleterious	4,07	23,7	0,16	0,45	disease	0,91	disease	0,8	disease	0,79	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,1	high_impact	3,05	0,46	0,8	7,3	9,49	P	0,61	P	0,97	disease_causing	0,99	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13582	13582	A	G	MI.21922	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1246	416	T	A	Acc/Gcc	-3,27	0	0	probably_damaging	1	neutral	0,57	neutral	3,78	neutral	0,86	deleterious	-4,33	medium_impact	2,13	neutral	0,69	neutral	0,73	deleterious	4,07	23,7	0,55	0,6	neutral	0,38	neutral	0,3	disease	0,65	neutral	0,42	2	deleterious	0,99	neutral	0,29	deleterious	1	deleterious	0,68	low_impact	-3,6	medium_impact	0,3	medium_impact	0,74	0,38	0,8	7,3	9,49	N	0,32	N	0,67	disease_causing	0,97	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13583	13583	C	A	MI.21923	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1247	416	T	N	aCc/aAc	5,67	1	0	probably_damaging	1	neutral	0,33	neutral	3,5	neutral	-2,78	deleterious	-4,42	high_impact	4,31	damaging	0,59	neutral	0,51	deleterious	3,77	23,4	0,41	0,5	disease	0,68	disease	0,78	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,06	high_impact	2,73	0,77	0,85	7,3	9,49	P	0,62	P	0,93	disease_causing	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13583	13583	C	T	MI.21924	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1247	416	T	I	aCc/aTc	5,67	1	0	probably_damaging	1	neutral	0,46	neutral	3,58	neutral	-1	deleterious	-5,09	medium_impact	2,72	damaging	0,6	neutral	0,56	deleterious	4,07	23,7	0,31	0,45	disease	0,67	disease	0,8	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,19	medium_impact	1,28	0,66	0,8	7,3	9,49	N	0,47	N	0,92	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13583	13583	C	G	MI.21925	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1247	416	T	S	aCc/aGc	5,67	1	0	probably_damaging	1	neutral	0,46	neutral	3,7	neutral	0,61	deleterious	-3,53	medium_impact	3,21	neutral	0,6	neutral	0,59	deleterious	3,6	23,2	0,44	0,55	neutral	0,39	disease	0,66	disease	0,64	disease	0,66	3	deleterious	0,99	neutral	0,23	deleterious	1	deleterious	0,71	low_impact	-3,6	medium_impact	0,19	medium_impact	1,73	0,48	0,8	7,3	9,49	P	0,54	P	0,85	disease_causing	0,88	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13585	13585	T	G	MI.21926	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1249	417	S	A	Tcc/Gcc	-5,56	0	0	benign	0,05	neutral	0,6	neutral	3,8	neutral	0,38	deleterious	-2,56	low_impact	1,08	neutral	0,79	neutral	0,58	deleterious	3,77	23,4	0,46	0,55	neutral	0,33	neutral	0,23	neutral	0,37	neutral	0,43	2	neutral	0,34	deleterious	0,78	neutral	-6	deleterious	0,63	medium_impact	0,47	medium_impact	0,33	medium_impact	-0,22	0,55	0,8	9,78	12,8	N	0,26	N	0,49	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13585	13585	T	A	MI.21927	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1249	417	S	T	Tcc/Acc	-5,56	0	0	possibly_damaging	0,61	neutral	0,63	neutral	3,69	neutral	-1,47	deleterious	-2,56	low_impact	0,84	neutral	0,77	neutral	0,46	deleterious	2,83	21,5	0,37	0,5	disease	0,7	neutral	0,37	neutral	0,37	disease	0,64	3	neutral	0,54	deleterious	0,51	neutral	-3	deleterious	0,7	medium_impact	-0,93	medium_impact	0,36	medium_impact	-0,44	0,62	0,8	9,78	12,8	N	0,22	N	0,7	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13585	13585	T	C	MI.21928	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1249	417	S	P	Tcc/Ccc	-5,56	0	0	probably_damaging	0,92	neutral	0,19	neutral	3,63	deleterious	-3,81	deleterious	-4,38	high_impact	3,69	neutral	0,71	damaging	0,11	deleterious	4,09	23,7	0,21	0,45	disease	0,88	disease	0,83	disease	0,73	disease	0,79	6	neutral	0,95	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-1,75	medium_impact	-0,12	high_impact	2,17	0,49	0,8	9,78	12,8	N	0,31	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13586	13586	C	G	MI.21929	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1250	417	S	C	tCc/tGc	0,17	0,01	0	probably_damaging	0,96	neutral	0,17	neutral	3,63	deleterious	-3,47	deleterious	-4,34	medium_impact	2,25	neutral	0,69	damaging	0,1	deleterious	3,73	23,3	0,28	0,45	disease	0,87	disease	0,71	disease	0,51	disease	0,66	3	neutral	0,98	neutral	0,11	deleterious	1	deleterious	0,76	low_impact	-2,06	medium_impact	-0,15	medium_impact	0,85	0,55	0,8	9,78	12,8	N	0,28	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6055	6055	A	C	MI.2193	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	152	51	D	A	gAc/gCc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,74	neutral	-2,71	deleterious	-4,87	medium_impact	3,43	neutral	0,63	neutral	0,42	deleterious	4,02	23,6	0,43	0,55	neutral	0,2	disease	0,9	disease	0,52	disease	0,67	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,07	0,36	0,9	3,7	7,26	P	0,49	N	0,85	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13586	13586	C	A	MI.21930	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1250	417	S	Y	tCc/tAc	0,17	0,01	0	probably_damaging	0,96	neutral	0,98	neutral	3,65	neutral	-2,91	deleterious	-5,22	medium_impact	3	neutral	0,76	damaging	0,12	deleterious	4,15	23,8	0,24	0,45	disease	0,8	disease	0,75	disease	0,63	disease	0,71	4	neutral	0,96	deleterious	0,51	deleterious	1	deleterious	0,78	low_impact	-2,06	medium_impact	1,17	medium_impact	1,54	0,63	0,8	9,78	12,8	N	0,18	N	0,99	polymorphism	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13586	13586	C	T	MI.21931	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1250	417	S	F	tCc/tTc	0,17	0,01	0	probably_damaging	0,94	neutral	0,69	neutral	3,73	neutral	-0,38	deleterious	-5,2	low_impact	1,6	neutral	0,75	damaging	0,13	deleterious	4,38	24,1	0,35	0,5	neutral	0,46	disease	0,76	disease	0,64	disease	0,56	1	neutral	0,93	neutral	0,38	neutral	-2	deleterious	0,72	low_impact	-1,88	medium_impact	0,42	medium_impact	0,26	0,36	0,8	9,78	12,8	N	0,18	N	0,99	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13588	13588	C	A	MI.21932	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1252	418	L	M	Ctg/Atg	-11,98	0	0	possibly_damaging	0,44	neutral	0,24	neutral	3,18	deleterious	-3,25	neutral	-0,02	low_impact	1,36	neutral	0,78	neutral	0,91	deleterious	2,38	18,67	0,29	0,45	disease	0,76	neutral	0,38	neutral	0,33	disease	0,66	3	neutral	0,73	neutral	0,4	neutral	-3	deleterious	0,74	medium_impact	-0,65	medium_impact	-0,04	medium_impact	0,04	0,73	0,85	13,43	16,18	N	0,43	N	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13588	13588	C	G	MI.21933	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1252	418	L	V	Ctg/Gtg	-11,98	0	0	possibly_damaging	0,69	neutral	0,5	neutral	3,25	neutral	-2,25	neutral	-1,91	medium_impact	2,95	neutral	0,61	neutral	0,62	deleterious	3,53	23,1	0,28	0,45	disease	0,73	disease	0,53	disease	0,61	disease	0,64	3	neutral	0,66	neutral	0,41	NA	0	deleterious	0,76	low_impact	-1,08	medium_impact	0,23	medium_impact	1,49	0,52	0,8	13,43	16,18	N	0,35	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13589	13589	T	G	MI.21934	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1253	418	L	R	cTg/cGg	-0,52	0	0	probably_damaging	0,94	neutral	0,35	neutral	3,12	deleterious	-5,91	deleterious	-4,21	high_impact	4,24	neutral	0,61	neutral	0,48	deleterious	4,28	24	0,12	0,4	disease	0,93	disease	0,87	disease	0,74	disease	0,85	7	neutral	0,95	neutral	0,21	deleterious	2	deleterious	0,9	low_impact	-1,88	medium_impact	0,08	high_impact	2,67	0,36	0,8	13,43	16,18	N	0,42	N	0,93	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13589	13589	T	C	MI.21935	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1253	418	L	P	cTg/cCg	-0,52	0	0	probably_damaging	0,98	neutral	0,2	neutral	3,12	deleterious	-6,34	deleterious	-5,11	high_impact	4,24	damaging	0,51	neutral	0,37	deleterious	3,97	23,6	0,14	0,4	disease	0,95	disease	0,88	disease	0,74	disease	0,86	7	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,91	low_impact	-2,35	medium_impact	-0,1	high_impact	2,67	0,58	0,8	13,43	16,18	N	0,43	N	0,93	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13589	13589	T	A	MI.21936	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1253	418	L	Q	cTg/cAg	-0,52	0	0	probably_damaging	0,97	neutral	0,29	neutral	3,12	deleterious	-6,09	deleterious	-3,88	high_impact	4,24	neutral	0,61	neutral	0,59	deleterious	4,29	24	0,14	0,4	disease	0,88	disease	0,73	disease	0,63	disease	0,77	5	neutral	0,97	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-2,18	medium_impact	0,02	high_impact	2,67	0,53	0,8	13,43	16,18	N	0,41	N	0,87	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13591	13591	A	T	MI.21937	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1255	419	T	S	Aca/Tca	-3,96	0	0	probably_damaging	1	neutral	0,55	neutral	3,17	neutral	-2,7	deleterious	-3,59	medium_impact	3,17	damaging	0,38	damaging	0,1	deleterious	3,36	22,9	0,3	0,45	disease	0,59	disease	0,62	disease	0,68	neutral	0,48	0	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,28	medium_impact	1,69	0,42	0,8	29,35	7,28	N	0,43	N	0,85	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13591	13591	A	C	MI.21938	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1255	419	T	P	Aca/Cca	-3,96	0	0	probably_damaging	1	neutral	0,24	neutral	3,06	deleterious	-6,23	deleterious	-5,39	high_impact	4,58	damaging	0,46	damaging	0,06	deleterious	3,59	23,2	0,17	0,45	disease	0,96	disease	0,8	disease	0,82	disease	0,85	7	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,04	high_impact	2,98	0,39	0,8	29,35	7,28	N	0,49	N	0,97	polymorphism	0,98	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13591	13591	A	G	MI.21939	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1255	419	T	A	Aca/Gca	-3,96	0	0	probably_damaging	1	neutral	0,58	neutral	3,16	neutral	-2,12	deleterious	-4,49	high_impact	4,93	damaging	0,5	damaging	0,07	deleterious	3,57	23,2	0,34	0,5	disease	0,64	disease	0,54	disease	0,66	disease	0,66	3	deleterious	0,99	neutral	0,29	deleterious	2	deleterious	0,74	low_impact	-3,6	medium_impact	0,31	high_impact	3,3	0,38	0,8	29,35	7,28	P	0,58	P	0,67	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6056	6056	C	G	MI.2194	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	153	51	D	E	gaC/gaG	7,07	1	0	probably_damaging	0,98	deleterious	0,02	neutral	2,76	neutral	-0,58	neutral	-2,42	medium_impact	2,48	damaging	0,49	neutral	0,33	deleterious	3,74	23,3	0,66	0,7	neutral	0,24	disease	0,88	neutral	0,3	disease	0,54	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-2,35	medium_impact	-0,75	medium_impact	1,19	0,38	0,9	3,7	7,26	P	0,55	P	0,65	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13592	13592	C	T	MI.21940	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1256	419	T	M	aCa/aTa	6,59	1	0	probably_damaging	1	neutral	0,34	neutral	3,07	deleterious	-4,78	deleterious	-5,39	high_impact	4,93	damaging	0,54	damaging	0,04	deleterious	4,15	23,8	0,29	0,45	disease	0,97	disease	0,8	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,07	high_impact	3,3	0,64	0,8	29,35	7,28	P	0,68	P	0,93	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13592	13592	C	A	MI.21941	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1256	419	T	K	aCa/aAa	6,59	1	0	probably_damaging	1	neutral	0,34	neutral	3,07	deleterious	-5,32	deleterious	-5,39	high_impact	4,93	damaging	0,49	damaging	0,04	deleterious	4,49	24,3	0,14	0,4	disease	0,93	disease	0,83	disease	0,81	disease	0,86	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,07	high_impact	3,3	0,61	0,8	29,35	7,28	P	0,73	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13594	13594	A	T	MI.21942	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1258	420	S	C	Agc/Tgc	-4,64	0	0	possibly_damaging	0,88	neutral	0,17	neutral	3,65	deleterious	-3,23	neutral	-1,03	low_impact	1,63	damaging	0,6	neutral	0,45	deleterious	3,49	23,1	0,18	0,45	disease	0,78	disease	0,71	disease	0,54	disease	0,7	4	neutral	0,93	neutral	0,15	neutral	-3	deleterious	0,74	low_impact	-1,57	medium_impact	-0,15	medium_impact	0,29	0,68	0,85	17,08	20,76	N	0,35	N	0,55	polymorphism	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13594	13594	A	C	MI.21943	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1258	420	S	R	Agc/Cgc	-4,64	0	0	possibly_damaging	0,7	neutral	0,36	neutral	3,64	deleterious	-3,58	neutral	-1,9	medium_impact	2,18	damaging	0,55	neutral	0,54	deleterious	3,65	23,2	0,12	0,4	disease	0,58	disease	0,87	disease	0,7	disease	0,8	6	neutral	0,74	neutral	0,33	NA	0	deleterious	0,71	low_impact	-1,1	medium_impact	0,1	medium_impact	0,79	0,7	0,85	17,08	20,76	N	0,31	N	0,59	polymorphism	0,97	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13594	13594	A	G	MI.21944	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1258	420	S	G	Agc/Ggc	-4,64	0	0	benign	0,01	neutral	0,37	neutral	3,69	neutral	-0,77	neutral	-1	low_impact	0,86	neutral	0,73	neutral	0,68	neutral	1,79	14,9	0,27	0,45	disease	0,63	disease	0,61	disease	0,53	disease	0,57	1	neutral	0,62	deleterious	0,68	neutral	-6	neutral	0,21	medium_impact	1,15	medium_impact	0,11	medium_impact	-0,42	0,65	0,8	17,08	20,76	N	0,27	N	0,05	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13595	13595	G	A	MI.21945	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1259	420	S	N	aGc/aAc	4,29	1	0	possibly_damaging	0,52	neutral	0,34	neutral	3,64	deleterious	-3,58	deleterious	-2,69	medium_impact	2,18	damaging	0,6	neutral	0,63	deleterious	1,98	16,07	0,45	0,55	disease	0,82	disease	0,69	disease	0,56	disease	0,73	5	neutral	0,64	neutral	0,41	NA	0	deleterious	0,58	medium_impact	-0,78	medium_impact	0,07	medium_impact	0,79	0,54	0,8	17,08	20,76	N	0,46	N	0,48	polymorphism	0,99	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13595	13595	G	T	MI.21946	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1259	420	S	I	aGc/aTc	4,29	1	0	possibly_damaging	0,63	neutral	0,44	neutral	3,72	neutral	-0,82	neutral	-1,93	low_impact	0,9	neutral	0,64	neutral	0,62	deleterious	3,97	23,6	0,27	0,45	neutral	0,42	disease	0,8	disease	0,57	disease	0,76	5	neutral	0,64	neutral	0,41	neutral	-3	deleterious	0,67	medium_impact	-0,97	medium_impact	0,18	medium_impact	-0,38	0,66	0,8	17,08	20,76	N	0,41	N	0,66	polymorphism	0,91	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13595	13595	G	C	MI.21947	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1259	420	S	T	aGc/aCc	4,29	1	0	benign	0,22	neutral	0,45	neutral	3,71	neutral	-0,86	neutral	-0,96	neutral_impact	-0,09	neutral	0,77	neutral	0,86	neutral	1,76	14,76	0,27	0,45	neutral	0,48	neutral	0,33	neutral	0,43	neutral	0,39	2	neutral	0,46	deleterious	0,62	neutral	-6	deleterious	0,45	medium_impact	-0,22	medium_impact	0,18	low_impact	-1,29	0,75	0,85	17,08	20,76	N	0,46	N	0,26	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13597	13597	G	A	MI.21948	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1261	421	A	T	Gcc/Acc	-5,79	0	0	benign	0,02	neutral	0,44	neutral	3,6	deleterious	-3,24	neutral	-1,04	low_impact	1,46	neutral	0,83	neutral	0,74	deleterious	4,31	24	0,46	0,55	disease	0,7	neutral	0,24	neutral	0,36	disease	0,57	1	neutral	0,54	deleterious	0,71	neutral	-6	deleterious	0,71	medium_impact	0,86	medium_impact	0,18	medium_impact	0,13	0,62	0,8	23,88	15,47	N	0,35	N	0,44	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13597	13597	G	C	MI.21949	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1261	421	A	P	Gcc/Ccc	-5,79	0	0	possibly_damaging	0,78	neutral	0,22	neutral	3,55	deleterious	-5,36	deleterious	-2,5	medium_impact	3,08	neutral	0,64	neutral	0,34	deleterious	3,98	23,6	0,13	0,4	disease	0,92	disease	0,83	disease	0,71	disease	0,83	7	neutral	0,86	neutral	0,22	NA	0	deleterious	0,88	low_impact	-1,27	medium_impact	-0,07	medium_impact	1,61	0,8	0,85	23,88	15,47	N	0,28	N	0,88	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6056	6056	C	A	MI.2195	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	153	51	D	E	gaC/gaA	7,07	1	0	probably_damaging	0,98	deleterious	0,02	neutral	2,76	neutral	-0,58	neutral	-2,42	medium_impact	2,48	damaging	0,49	neutral	0,33	deleterious	4,05	23,7	0,66	0,7	neutral	0,24	disease	0,88	neutral	0,3	disease	0,54	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-2,35	medium_impact	-0,75	medium_impact	1,19	0,38	0,9	3,7	7,26	P	0,55	P	0,65	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13597	13597	G	T	MI.21950	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1261	421	A	S	Gcc/Tcc	-5,79	0	0	benign	0,04	neutral	0,45	neutral	3,63	neutral	-2,95	neutral	-1,51	neutral_impact	0,76	neutral	0,85	neutral	0,96	deleterious	3,81	23,4	0,31	0,45	disease	0,67	neutral	0,47	disease	0,54	disease	0,65	3	neutral	0,52	deleterious	0,71	neutral	-6	deleterious	0,75	medium_impact	0,57	medium_impact	0,18	medium_impact	-0,51	0,75	0,85	23,88	15,47	N	0,32	N	0,52	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13598	13598	C	G	MI.21951	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1262	421	A	G	gCc/gGc	-0,75	0	0	benign	0,32	neutral	0,35	neutral	3,59	neutral	-2,92	deleterious	-2,8	medium_impact	2,19	neutral	0,83	neutral	0,61	deleterious	4,13	23,8	0,21	0,45	disease	0,66	disease	0,55	disease	0,57	disease	0,69	4	neutral	0,58	deleterious	0,52	neutral	-3	deleterious	0,73	medium_impact	-0,44	medium_impact	0,08	medium_impact	0,8	0,77	0,85	23,88	15,47	N	0,31	N	0,51	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13598	13598	C	T	MI.21952	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1262	421	A	V	gCc/gTc	-0,75	0	0	benign	0,23	neutral	0,53	neutral	3,71	neutral	-1,09	neutral	1,02	neutral_impact	-0,28	neutral	0,79	neutral	0,98	deleterious	1,92	15,7	0,39	0,5	neutral	0,49	neutral	0,15	neutral	0,27	neutral	0,2	6	neutral	0,36	deleterious	0,65	neutral	-6	deleterious	0,65	medium_impact	-0,25	medium_impact	0,26	low_impact	-1,46	0,77	0,85	23,88	15,47	N	0,32	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13598	13598	C	A	MI.21953	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1262	421	A	D	gCc/gAc	-0,75	0	0	possibly_damaging	0,54	neutral	0,24	neutral	3,55	deleterious	-5,99	deleterious	-3,14	medium_impact	3,08	neutral	0,69	neutral	0,41	deleterious	4,69	24,6	0,13	0,4	disease	0,94	disease	0,8	disease	0,71	disease	0,84	7	neutral	0,75	neutral	0,35	NA	0	deleterious	0,84	medium_impact	-0,81	medium_impact	-0,04	medium_impact	1,61	0,63	0,8	23,88	15,47	N	0,3	N	0,92	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13600	13600	T	A	MI.21954	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1264	422	Y	N	Tat/Aat	-4,87	0	0	probably_damaging	1	neutral	0,31	deleterious	-1,82	deleterious	-10,3	deleterious	-8,09	high_impact	3,94	damaging	0,22	neutral	0,42	deleterious	4,18	23,8	0,24	0,45	disease	0,9	disease	0,82	disease	0,73	disease	0,8	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,04	high_impact	2,4	0,25	0,8	28,19	7,1	P	0,83	P	0,99	polymorphism	0,94	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13600	13600	T	C	MI.21955	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1264	422	Y	H	Tat/Cat	-4,87	0	0	probably_damaging	1	neutral	0,52	deleterious	-1,81	deleterious	-9,36	deleterious	-4,49	high_impact	3,94	damaging	0,33	neutral	0,32	deleterious	3,72	23,3	0,28	0,45	disease	0,92	disease	0,8	disease	0,78	disease	0,86	7	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,25	high_impact	2,4	0,41	0,8	28,19	7,1	P	0,57	P	0,98	polymorphism	0,99	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13600	13600	T	G	MI.21956	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1264	422	Y	D	Tat/Gat	-4,87	0	0	probably_damaging	1	neutral	0,2	deleterious	-1,82	deleterious	-10,76	deleterious	-8,98	high_impact	3,94	damaging	0,37	neutral	0,38	deleterious	4,13	23,8	0,15	0,4	disease	0,96	disease	0,88	disease	0,8	disease	0,86	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,1	high_impact	2,4	0,28	0,8	28,19	7,1	P	0,62	P	0,96	polymorphism	0,95	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13601	13601	A	T	MI.21957	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1265	422	Y	F	tAt/tTt	7,27	1	0	probably_damaging	1	neutral	0,72	deleterious	-1,76	deleterious	-7,09	deleterious	-3,59	high_impact	3,94	damaging	0,28	neutral	0,36	deleterious	3,63	23,2	0,27	0,45	disease	0,8	disease	0,79	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,46	high_impact	2,4	0,33	0,8	28,19	7,1	P	0,91	P	0,8	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13601	13601	A	G	MI.21958	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1265	422	Y	C	tAt/tGt	7,27	1	0	probably_damaging	1	neutral	0,17	deleterious	-1,82	deleterious	-11,54	deleterious	-8,09	high_impact	3,94	damaging	0,3	damaging	0,28	deleterious	3,7	23,3	0,25	0,45	disease	0,82	disease	0,84	disease	0,77	disease	0,8	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,15	high_impact	2,4	0,24	0,8	28,19	7,1	P	0,71	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13601	13601	A	C	MI.21959	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1265	422	Y	S	tAt/tCt	7,27	1	0	probably_damaging	1	neutral	0,45	deleterious	-1,82	deleterious	-10,03	deleterious	-8,09	high_impact	3,94	damaging	0,34	neutral	0,53	deleterious	3,89	23,5	0,21	0,45	disease	0,85	disease	0,84	disease	0,72	disease	0,79	6	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,18	high_impact	2,4	0,26	0,8	28,19	7,1	P	0,72	P	0,97	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6057	6057	C	G	MI.2196	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	154	52	H	D	Cac/Gac	-2,42	0	0	benign	0,2	deleterious	0	neutral	3	neutral	2,49	neutral	-0,72	low_impact	1,73	damaging	0,53	neutral	0,49	deleterious	3,72	23,3	0,26	0,55	neutral	0,14	disease	0,83	disease	0,71	disease	0,79	6	deleterious	1	neutral	0,4	neutral	-2	neutral	0,35	medium_impact	-0,19	low_impact	-1,48	medium_impact	0,5	0,62	0,9	13,84	68,8	N	0,38	N	0,36	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13603	13603	A	C	MI.21960	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1267	423	S	R	Agc/Cgc	-4,19	0	0	probably_damaging	0,96	neutral	0,35	neutral	-0,42	deleterious	-7,59	deleterious	-4,49	high_impact	3,88	damaging	0,58	neutral	0,45	deleterious	3,82	23,4	0,09	0,35	disease	0,89	disease	0,8	disease	0,77	disease	0,83	7	neutral	0,96	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-2,06	medium_impact	0,08	high_impact	2,34	0,73	0,85	23,05	6,96	N	0,41	N	0,99	disease_causing	0,99	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13603	13603	A	G	MI.21961	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1267	423	S	G	Agc/Ggc	-4,19	0	0	possibly_damaging	0,73	neutral	0,33	neutral	-0,39	deleterious	-5,91	deleterious	-3,59	high_impact	3,52	damaging	0,56	neutral	0,58	deleterious	3,48	23,1	0,25	0,45	disease	0,86	disease	0,64	disease	0,68	disease	0,72	4	neutral	0,77	neutral	0,3	deleterious	1	deleterious	0,76	low_impact	-1,16	medium_impact	0,06	high_impact	2,01	0,71	0,85	23,05	6,96	N	0,37	N	0,86	disease_causing	0,93	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13603	13603	A	T	MI.21962	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1267	423	S	C	Agc/Tgc	-4,19	0	0	probably_damaging	0,99	neutral	0,18	neutral	-0,39	deleterious	-5,8	deleterious	-4,49	high_impact	3,88	damaging	0,58	neutral	0,45	deleterious	3,38	23	0,14	0,4	disease	0,91	disease	0,7	disease	0,66	disease	0,79	6	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,8	low_impact	-2,64	medium_impact	-0,13	high_impact	2,34	0,61	0,8	23,05	6,96	N	0,35	N	0,99	disease_causing	0,98	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13604	13604	G	C	MI.21963	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1268	423	S	T	aGc/aCc	8,42	1	0	benign	0,26	neutral	0,39	neutral	-0,24	deleterious	-3,56	deleterious	-2,69	medium_impact	2,35	neutral	0,61	neutral	0,66	deleterious	3,48	23,1	0,29	0,45	disease	0,62	neutral	0,41	disease	0,61	disease	0,56	1	neutral	0,53	deleterious	0,57	neutral	-3	deleterious	0,74	medium_impact	-0,32	medium_impact	0,13	medium_impact	0,94	0,78	0,85	23,05	6,96	P	0,6	P	0,71	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13604	13604	G	T	MI.21964	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1268	423	S	I	aGc/aTc	8,42	1	0	probably_damaging	0,94	neutral	0,4	neutral	-0,42	deleterious	-7,51	deleterious	-5,39	high_impact	3,88	damaging	0,57	neutral	0,56	deleterious	4,22	23,9	0,16	0,45	disease	0,68	disease	0,82	disease	0,68	disease	0,7	4	neutral	0,94	neutral	0,23	deleterious	2	deleterious	0,78	low_impact	-1,88	medium_impact	0,14	high_impact	2,34	0,77	0,85	23,05	6,96	P	0,53	P	0,99	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13604	13604	G	A	MI.21965	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1268	423	S	N	aGc/aAc	8,42	1	0	benign	0,17	neutral	0,31	neutral	-0,42	deleterious	-7,02	deleterious	-2,68	medium_impact	3,33	damaging	0,55	neutral	0,52	deleterious	3,68	23,3	0,4	0,5	disease	0,91	disease	0,64	disease	0,61	disease	0,68	4	neutral	0,63	deleterious	0,57	neutral	-3	deleterious	0,8	medium_impact	-0,09	medium_impact	0,04	medium_impact	1,84	0,49	0,8	23,05	6,96	P	0,59	P	0,87	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13606	13606	A	C	MI.21966	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1270	424	T	P	Act/Cct	-0,75	0	0	possibly_damaging	0,86	neutral	0,18	neutral	0,9	deleterious	-3,84	deleterious	-4,41	medium_impact	2,58	neutral	0,64	neutral	0,39	deleterious	3,56	23,1	0,14	0,4	disease	0,88	disease	0,79	disease	0,66	disease	0,8	6	neutral	0,92	neutral	0,16	NA	0	deleterious	0,87	low_impact	-1,5	medium_impact	-0,13	medium_impact	1,15	0,51	0,8	27,53	18,29	N	0,28	N	0,91	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13606	13606	A	T	MI.21967	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1270	424	T	S	Act/Tct	-0,75	0	0	possibly_damaging	0,45	neutral	0,53	neutral	0,94	neutral	-1,23	deleterious	-2,61	low_impact	1,77	neutral	0,86	neutral	0,65	deleterious	3,38	23	0,41	0,5	disease	0,69	neutral	0,38	disease	0,52	disease	0,64	3	neutral	0,45	deleterious	0,54	neutral	-3	deleterious	0,74	medium_impact	-0,66	medium_impact	0,26	medium_impact	0,41	0,7	0,85	27,53	18,29	N	0,26	N	0,23	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13606	13606	A	G	MI.21968	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1270	424	T	A	Act/Gct	-0,75	0	0	benign	0,07	neutral	0,5	neutral	0,99	neutral	-0,04	deleterious	-3,34	medium_impact	2,23	neutral	0,84	neutral	0,77	deleterious	2,37	18,59	0,52	0,6	neutral	0,47	neutral	0,28	disease	0,55	neutral	0,49	0	neutral	0,44	deleterious	0,72	neutral	-3	deleterious	0,69	medium_impact	0,32	medium_impact	0,23	medium_impact	0,83	0,42	0,8	27,53	18,29	N	0,35	N	0,49	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13607	13607	C	G	MI.21969	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1271	424	T	S	aCt/aGt	-0,06	0	0	possibly_damaging	0,45	neutral	0,53	neutral	0,94	neutral	-1,23	deleterious	-2,61	low_impact	1,77	neutral	0,86	neutral	0,65	deleterious	3,56	23,1	0,41	0,5	disease	0,69	neutral	0,38	disease	0,52	disease	0,64	3	neutral	0,45	deleterious	0,54	neutral	-3	deleterious	0,74	medium_impact	-0,66	medium_impact	0,26	medium_impact	0,41	0,7	0,85	27,53	18,29	N	0,26	N	0,23	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6057	6057	C	A	MI.2197	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	154	52	H	N	Cac/Aac	-2,42	0	0	benign	0,2	deleterious	0	neutral	2,96	neutral	1,31	neutral	-0,55	low_impact	1,21	neutral	0,6	neutral	0,63	deleterious	3,86	23,5	0,55	0,6	neutral	0,18	disease	0,81	disease	0,53	disease	0,71	4	deleterious	1	neutral	0,4	neutral	-2	neutral	0,34	medium_impact	-0,19	low_impact	-1,48	medium_impact	0,02	0,58	0,9	13,84	68,8	N	0,37	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13607	13607	C	A	MI.21970	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1271	424	T	N	aCt/aAt	-0,06	0	0	possibly_damaging	0,82	neutral	0,27	neutral	0,9	deleterious	-3,42	deleterious	-3,65	medium_impact	2,58	neutral	0,72	neutral	0,52	deleterious	3,65	23,2	0,36	0,5	disease	0,86	disease	0,59	disease	0,56	disease	0,7	4	neutral	0,86	neutral	0,23	NA	0	deleterious	0,8	low_impact	-1,37	medium_impact	-0,01	medium_impact	1,15	0,7	0,85	27,53	18,29	N	0,32	N	0,68	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13607	13607	C	T	MI.21971	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1271	424	T	I	aCt/aTt	-0,06	0	0	benign	0,07	neutral	0,51	neutral	1,01	neutral	-0,51	deleterious	-3,79	low_impact	0,82	neutral	0,69	neutral	0,69	deleterious	2,34	18,44	0,35	0,5	neutral	0,42	neutral	0,43	neutral	0,38	neutral	0,47	1	neutral	0,43	deleterious	0,72	neutral	-6	deleterious	0,69	medium_impact	0,32	medium_impact	0,24	medium_impact	-0,45	0,54	0,8	27,53	18,29	N	0,35	N	0,39	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13609	13609	C	G	MI.21972	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1273	425	R	G	Cga/Gga	-7,62	0	0	probably_damaging	1	neutral	0,41	deleterious	-2,06	deleterious	-9,94	deleterious	-6,29	high_impact	3,92	damaging	0,5	damaging	0,09	deleterious	4,34	24	0,24	0,45	disease	0,9	disease	0,74	disease	0,79	disease	0,83	7	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,15	high_impact	2,38	0,27	0,8	29,19	7,21	N	0,34	N	0,97	polymorphism	0,96	0,43	rs28439808	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13609	13609	C	T	MI.21973	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1273	425	R	W	Cga/Tga	-7,62	0	0	probably_damaging	1	neutral	0,17	deleterious	-2,07	deleterious	-12,5	deleterious	-7,19	high_impact	3,92	neutral	0,61	damaging	0,05	deleterious	5,31	25,8	0,28	0,45	disease	0,86	disease	0,83	disease	0,8	disease	0,84	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,15	high_impact	2,38	0,55	0,8	29,19	7,21	N	0,33	N	1	polymorphism	0,88	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13610	13610	G	A	MI.21974	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1274	425	R	Q	cGa/cAa	3,38	0,99	0	probably_damaging	1	neutral	0,25	deleterious	-2,05	deleterious	-9,49	deleterious	-3,59	medium_impact	2,82	damaging	0,41	damaging	0,09	deleterious	4,61	24,4	0,38	0,5	disease	0,82	disease	0,75	disease	0,8	disease	0,72	4	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	-0,03	medium_impact	1,37	0,61	0,8	29,19	7,21	P	0,68	P	0,99	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13610	13610	G	C	MI.21975	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1274	425	R	P	cGa/cCa	3,38	0,99	0	probably_damaging	1	neutral	0,23	deleterious	-2,06	deleterious	-10,71	deleterious	-6,29	high_impact	3,92	damaging	0,53	damaging	0,07	deleterious	4,28	24	0,19	0,45	disease	0,9	disease	0,83	disease	0,85	disease	0,84	7	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,06	high_impact	2,38	0,26	0,8	29,19	7,21	N	0,46	N	0,99	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13610	13610	G	T	MI.21976	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1274	425	R	L	cGa/cTa	3,38	0,99	0	probably_damaging	1	neutral	0,98	deleterious	-2,06	deleterious	-10,19	deleterious	-6,29	high_impact	3,92	damaging	0,5	damaging	0,06	deleterious	4,39	24,1	0,23	0,45	disease	0,79	disease	0,87	disease	0,77	disease	0,82	6	deleterious	1	deleterious	0,49	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	1,17	high_impact	2,38	0,33	0,8	29,19	7,21	P	0,53	P	1	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13612	13612	A	G	MI.21977	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1276	426	M	V	Ata/Gta	-0,52	0,17	0	benign	0,01	neutral	0,55	neutral	0,98	neutral	-0,19	neutral	1,27	low_impact	0,82	neutral	0,82	neutral	0,82	neutral	-0,64	0,1	0,56	0,6	neutral	0,34	neutral	0,16	neutral	0,45	neutral	0,3	4	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,15	medium_impact	1,15	medium_impact	0,28	medium_impact	-0,45	0,67	0,85	18,57	19,09	N	0,29	N	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13612	13612	A	C	MI.21978	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1276	426	M	L	Ata/Cta	-0,52	0,17	0	benign	0	neutral	0,7	neutral	1,61	neutral	2,75	neutral	0,57	neutral_impact	0,18	neutral	0,77	neutral	0,83	deleterious	0,26	5,27	0,42	0,5	neutral	0,38	neutral	0,2	neutral	0,42	neutral	0,37	3	neutral	0,29	deleterious	0,85	neutral	-6	neutral	0,13	high_impact	2,1	medium_impact	0,44	low_impact	-1,04	0,65	0,8	18,57	19,09	N	0,34	N	0,4	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13612	13612	A	T	MI.21979	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1276	426	M	L	Ata/Tta	-0,52	0,17	0	benign	0	neutral	0,7	neutral	1,61	neutral	2,75	neutral	0,57	neutral_impact	0,18	neutral	0,77	neutral	0,83	deleterious	0,36	6,3	0,42	0,5	neutral	0,38	neutral	0,2	neutral	0,42	neutral	0,37	3	neutral	0,29	deleterious	0,85	neutral	-6	neutral	0,13	high_impact	2,1	medium_impact	0,44	low_impact	-1,04	0,65	0,8	18,57	19,09	N	0,34	N	0,4	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6057	6057	C	T	MI.2198	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	154	52	H	Y	Cac/Tac	-2,42	0	0	possibly_damaging	0,53	deleterious	0,03	neutral	2,98	neutral	-0,85	neutral	-1,03	medium_impact	2,74	neutral	0,6	neutral	0,62	deleterious	3,57	23,2	0,57	0,6	neutral	0,38	disease	0,81	disease	0,68	disease	0,78	6	neutral	0,97	neutral	0,25	deleterious	4	deleterious	0,58	medium_impact	-0,81	medium_impact	-0,65	medium_impact	1,43	0,43	0,9	13,84	68,8	N	0,38	N	0,34	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13613	13613	T	C	MI.21980	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1277	426	M	T	aTa/aCa	1,31	0,82	0	benign	0	neutral	0,39	neutral	0,89	neutral	-2,24	neutral	-2,11	low_impact	1,66	neutral	0,86	neutral	0,78	deleterious	0,35	6,17	0,32	0,5	disease	0,7	neutral	0,36	disease	0,63	disease	0,66	3	neutral	0,61	deleterious	0,7	neutral	-6	neutral	0,42	high_impact	2,1	medium_impact	0,13	medium_impact	0,31	0,48	0,8	18,57	19,09	N	0,32	N	0,13	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13613	13613	T	A	MI.21981	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1277	426	M	K	aTa/aAa	1,31	0,82	0	benign	0,23	neutral	0,29	neutral	0,87	deleterious	-3,63	deleterious	-3,74	medium_impact	2,7	neutral	0,72	neutral	0,46	deleterious	2,6	20,2	0,16	0,45	disease	0,84	disease	0,59	disease	0,71	disease	0,75	5	neutral	0,65	deleterious	0,53	neutral	-3	deleterious	0,56	medium_impact	-0,25	medium_impact	0,02	medium_impact	1,26	0,5	0,8	18,57	19,09	N	0,32	N	0,88	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13614	13614	A	T	MI.21982	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1278	426	M	I	atA/atT	5,67	0,97	0	benign	0,01	neutral	0,5	neutral	1,2	neutral	1,38	neutral	2,06	neutral_impact	-0,36	neutral	0,8	neutral	0,97	neutral	-1	0,02	0,47	0,55	neutral	0,34	neutral	0,09	neutral	0,34	neutral	0,21	6	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,23	low_impact	-1,53	0,71	0,85	18,57	19,09	P	0,55	P	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13614	13614	A	C	MI.21983	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1278	426	M	I	atA/atC	5,67	0,97	0	benign	0,01	neutral	0,5	neutral	1,2	neutral	1,38	neutral	2,06	neutral_impact	-0,36	neutral	0,8	neutral	0,97	neutral	-1,06	0,01	0,47	0,55	neutral	0,34	neutral	0,09	neutral	0,34	neutral	0,21	6	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,23	low_impact	-1,53	0,71	0,85	18,57	19,09	P	0,55	P	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13615	13615	A	C	MI.21984	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1279	427	I	L	Att/Ctt	-9	0	0	benign	0,29	neutral	1	neutral	0,82	neutral	-0,42	neutral	-1,57	low_impact	1,91	neutral	0,81	neutral	0,92	deleterious	2,02	16,34	0,25	0,45	neutral	0,42	neutral	0,47	neutral	0,36	neutral	0,47	1	neutral	0,29	deleterious	0,86	neutral	-6	neutral	0,22	medium_impact	-0,38	high_impact	1,89	medium_impact	0,54	0,68	0,85	7,79	15,96	N	0,24	N	0,23	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13615	13615	A	G	MI.21985	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1279	427	I	V	Att/Gtt	-9	0	0	benign	0,05	neutral	0,8	neutral	0,91	neutral	-0,22	neutral	-0,65	low_impact	1,42	neutral	0,82	neutral	0,97	neutral	-0,3	0,67	0,52	0,6	neutral	0,47	neutral	0,1	neutral	0,36	neutral	0,3	4	neutral	0,12	deleterious	0,88	neutral	-6	neutral	0,11	medium_impact	0,47	medium_impact	0,57	medium_impact	0,09	0,58	0,8	7,79	15,96	N	0,32	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13615	13615	A	T	MI.21986	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1279	427	I	F	Att/Ttt	-9	0	0	possibly_damaging	0,88	neutral	0,78	neutral	0,73	neutral	-1,44	deleterious	-3,43	medium_impact	2,6	neutral	0,72	neutral	0,53	deleterious	3,71	23,3	0,35	0,5	disease	0,51	disease	0,63	disease	0,54	disease	0,56	1	neutral	0,85	neutral	0,45	NA	0	deleterious	0,66	low_impact	-1,57	medium_impact	0,54	medium_impact	1,17	0,77	0,85	7,79	15,96	N	0,21	N	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13616	13616	T	G	MI.21987	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1280	427	I	S	aTt/aGt	0,63	0,02	0	possibly_damaging	0,86	neutral	0,54	neutral	0,81	deleterious	-3,5	deleterious	-5,09	medium_impact	3,15	neutral	0,73	neutral	0,52	deleterious	4,24	23,9	0,26	0,45	disease	0,8	disease	0,76	disease	0,59	disease	0,7	4	neutral	0,84	neutral	0,34	NA	0	deleterious	0,72	low_impact	-1,5	medium_impact	0,27	medium_impact	1,67	0,5	0,8	7,79	15,96	N	0,27	N	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13616	13616	T	A	MI.21988	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1280	427	I	N	aTt/aAt	0,63	0,02	0	probably_damaging	0,96	neutral	0,25	neutral	0,68	deleterious	-4,86	deleterious	-5,99	medium_impact	3,5	neutral	0,69	neutral	0,39	deleterious	4,6	24,4	0,2	0,45	disease	0,84	disease	0,77	disease	0,61	disease	0,74	5	neutral	0,97	neutral	0,15	deleterious	1	deleterious	0,8	low_impact	-2,06	medium_impact	-0,03	medium_impact	1,99	0,58	0,8	7,79	15,96	N	0,33	N	0,97	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13616	13616	T	C	MI.21989	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1280	427	I	T	aTt/aCt	0,63	0,02	0	possibly_damaging	0,76	neutral	0,45	neutral	0,8	neutral	-2,87	deleterious	-4,12	low_impact	1,88	neutral	0,72	neutral	0,79	deleterious	3,08	22,5	0,33	0,5	disease	0,63	neutral	0,35	neutral	0,43	disease	0,61	2	neutral	0,75	neutral	0,35	neutral	-3	deleterious	0,55	low_impact	-1,22	medium_impact	0,18	medium_impact	0,51	0,64	0,8	7,79	15,96	N	0,4	N	0,95	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6058	6058	A	T	MI.2199	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	155	52	H	L	cAc/cTc	5,68	1	0	benign	0,3	deleterious	0	neutral	3,14	neutral	0,25	neutral	-1,97	medium_impact	2,11	neutral	0,62	neutral	0,57	deleterious	3,77	23,4	0,29	0,55	neutral	0,16	disease	0,84	disease	0,68	disease	0,8	6	deleterious	1	neutral	0,35	deleterious	1	neutral	0,43	medium_impact	-0,41	low_impact	-1,48	medium_impact	0,85	0,37	0,9	13,84	68,8	P	0,49	N	0,52	disease_causing	0,97	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13617	13617	T	A	MI.21990	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1281	427	I	M	atT/atA	2,92	0,13	0,12	benign	0,4	neutral	0,65	neutral	0,73	neutral	-2,3	neutral	-2,27	low_impact	1,6	neutral	0,84	neutral	0,97	deleterious	2,65	20,5	0,37	0,5	disease	0,71	neutral	0,4	neutral	0,39	disease	0,64	3	neutral	0,33	deleterious	0,63	neutral	-6	deleterious	0,68	medium_impact	-0,58	medium_impact	0,38	medium_impact	0,26	0,8	0,85	7,79	15,96	N	0,35	N	0,26	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13617	13617	T	G	MI.21991	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1281	427	I	M	atT/atG	2,92	0,13	0,12	benign	0,4	neutral	0,65	neutral	0,73	neutral	-2,3	neutral	-2,27	low_impact	1,6	neutral	0,84	neutral	0,97	deleterious	2,33	18,38	0,37	0,5	disease	0,71	neutral	0,4	neutral	0,39	disease	0,64	3	neutral	0,33	deleterious	0,63	neutral	-6	deleterious	0,68	medium_impact	-0,58	medium_impact	0,38	medium_impact	0,26	0,8	0,85	7,79	15,96	N	0,35	N	0,26	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13618	13618	C	A	MI.21992	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1282	428	L	I	Ctt/Att	-5,1	0	0	benign	0,05	neutral	0,41	neutral	0,91	neutral	-0,86	neutral	-0,06	neutral_impact	-0,03	neutral	0,79	neutral	0,81	deleterious	3,15	22,6	0,44	0,55	disease	0,57	neutral	0,32	neutral	0,27	disease	0,6	2	neutral	0,55	deleterious	0,68	neutral	-6	deleterious	0,71	medium_impact	0,47	medium_impact	0,15	low_impact	-1,23	0,56	0,8	27,53	21,18	N	0,32	N	0,3	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13618	13618	C	G	MI.21993	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1282	428	L	V	Ctt/Gtt	-5,1	0	0	benign	0,41	neutral	0,46	neutral	0,91	neutral	-0,8	neutral	-0,91	neutral_impact	0,68	neutral	0,75	neutral	0,78	deleterious	3,53	23,1	0,46	0,55	disease	0,5	neutral	0,42	disease	0,51	neutral	0,22	6	neutral	0,48	deleterious	0,53	neutral	-6	deleterious	0,71	medium_impact	-0,6	medium_impact	0,19	medium_impact	-0,58	0,68	0,85	27,53	21,18	N	0,33	N	0,27	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13618	13618	C	T	MI.21994	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1282	428	L	F	Ctt/Ttt	-5,1	0	0	benign	0,05	neutral	0,74	neutral	1,01	neutral	0,05	neutral	4,89	neutral_impact	-1,28	neutral	0,82	neutral	0,97	neutral	1,33	12,42	0,46	0,55	neutral	0,34	neutral	0,06	neutral	0,21	neutral	0,23	5	neutral	0,18	deleterious	0,85	neutral	-6	deleterious	0,65	medium_impact	0,47	medium_impact	0,48	low_impact	-2,37	0,54	0,8	27,53	21,18	N	0,28	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13619	13619	T	A	MI.21995	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1283	428	L	H	cTt/cAt	-0,06	0	0	probably_damaging	0,98	neutral	0,45	neutral	0,8	deleterious	-3,8	neutral	-0,78	low_impact	1,17	neutral	0,81	neutral	0,84	deleterious	4,04	23,7	0,2	0,45	disease	0,85	disease	0,59	disease	0,54	disease	0,68	4	neutral	0,98	neutral	0,24	neutral	-2	deleterious	0,8	low_impact	-2,35	medium_impact	0,18	medium_impact	-0,13	0,52	0,8	27,53	21,18	N	0,28	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13619	13619	T	C	MI.21996	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1283	428	L	P	cTt/cCt	-0,06	0	0	probably_damaging	0,95	neutral	0,17	neutral	0,8	deleterious	-3,87	deleterious	-3,51	low_impact	1,72	damaging	0,59	neutral	0,44	deleterious	3,85	23,4	0,18	0,45	disease	0,86	disease	0,84	disease	0,67	disease	0,83	7	neutral	0,97	neutral	0,11	neutral	-2	deleterious	0,89	low_impact	-1,96	medium_impact	-0,15	medium_impact	0,37	0,61	0,8	27,53	21,18	N	0,27	N	0,93	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13619	13619	T	G	MI.21997	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1283	428	L	R	cTt/cGt	-0,06	0	0	probably_damaging	0,93	neutral	0,34	neutral	0,8	deleterious	-3,29	deleterious	-2,61	low_impact	1,72	neutral	0,69	neutral	0,51	deleterious	4,18	23,8	0,2	0,45	disease	0,56	disease	0,83	disease	0,65	disease	0,79	6	neutral	0,94	neutral	0,21	neutral	-2	deleterious	0,82	low_impact	-1,81	medium_impact	0,07	medium_impact	0,37	0,68	0,85	27,53	21,18	N	0,27	N	0,74	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13621	13621	C	T	MI.21998	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1285	429	L	F	Ctc/Ttc	-2,81	0	0	benign	0,02	neutral	0,91	neutral	1,01	neutral	0,08	neutral	3,85	neutral_impact	-0,6	neutral	0,85	neutral	0,98	neutral	-0,56	0,16	0,47	0,55	disease	0,6	neutral	0,06	neutral	0,27	neutral	0,3	4	neutral	0,05	deleterious	0,95	neutral	-6	neutral	0,15	medium_impact	0,86	medium_impact	0,79	low_impact	-1,75	0,71	0,85	18,57	19,16	N	0,26	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13621	13621	C	A	MI.21999	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1285	429	L	I	Ctc/Atc	-2,81	0	0	benign	0,36	neutral	0,46	neutral	0,88	neutral	-1,28	neutral	-0,23	medium_impact	2,24	neutral	0,74	neutral	0,67	deleterious	2,49	19,42	0,44	0,55	disease	0,63	neutral	0,45	disease	0,56	disease	0,65	3	neutral	0,46	deleterious	0,55	neutral	-3	neutral	0,43	medium_impact	-0,51	medium_impact	0,19	medium_impact	0,84	0,7	0,85	18,57	19,16	N	0,35	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8536	8536	A	C	MI.22	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	10	4	N	H	Aat/Cat	6,84	1	0	possibly_damaging	0,54	deleterious	0	neutral	4,42	neutral	-2,41	deleterious	-3,52	medium_impact	2,85	neutral	0,86	neutral	0,29	deleterious	3,8	23,4	0,66	0,7	disease	0,85	neutral	0,39	disease	0,62	disease	0,68	4	deleterious	1	neutral	0,23	deleterious	4	deleterious	0,55	medium_impact	-0,82	low_impact	-1,4	medium_impact	1,35	0,34	0,9	41,59	7,51	P	0,63	P	0,81	disease_causing	0,99	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8630	8630	A	C	MI.220	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	104	35	K	T	aAa/aCa	-0,1	0	0	benign	0,28	neutral	0,41	neutral	4,41	neutral	0,3	neutral	-1,15	neutral_impact	-1,4	neutral	0,86	neutral	0,95	deleterious	0,04	3,02	0,44	0,65	disease	0,58	neutral	0,21	neutral	0,3	neutral	0,48	1	neutral	0,5	deleterious	0,57	neutral	-6	deleterious	0,45	medium_impact	-0,37	medium_impact	0,2	low_impact	-2,3	0,42	0,9	20,35	18,29	N	0,34	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6058	6058	A	C	MI.2200	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	155	52	H	P	cAc/cCc	5,68	1	0	possibly_damaging	0,66	deleterious	0	neutral	2,96	neutral	-0,22	neutral	-1,35	medium_impact	2,54	damaging	0,49	neutral	0,39	deleterious	3,08	22,5	0,21	0,55	neutral	0,3	disease	0,93	disease	0,78	disease	0,83	7	deleterious	1	neutral	0,17	deleterious	4	deleterious	0,63	low_impact	-1,03	low_impact	-1,48	medium_impact	1,25	0,43	0,9	13,84	68,8	P	0,54	P	0,59	disease_causing	0,96	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13621	13621	C	G	MI.22000	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1285	429	L	V	Ctc/Gtc	-2,81	0	0	benign	0,25	neutral	0,61	neutral	0,9	neutral	-0,99	neutral	-0,95	medium_impact	2,24	neutral	0,72	neutral	0,67	deleterious	1,82	15,1	0,45	0,55	disease	0,71	disease	0,5	disease	0,58	disease	0,68	4	neutral	0,28	deleterious	0,68	neutral	-3	neutral	0,38	medium_impact	-0,29	medium_impact	0,34	medium_impact	0,84	0,7	0,85	18,57	19,16	N	0,26	N	0,24	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13622	13622	T	G	MI.22001	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1286	429	L	R	cTc/cGc	0,63	0	0	possibly_damaging	0,6	neutral	0,28	neutral	0,82	neutral	-2,71	deleterious	-2,65	medium_impact	2,24	neutral	0,66	neutral	0,58	deleterious	3,9	23,5	0,21	0,45	neutral	0,49	disease	0,85	disease	0,71	disease	0,79	6	neutral	0,73	neutral	0,34	NA	0	deleterious	0,67	medium_impact	-0,91	medium_impact	0,01	medium_impact	0,84	0,66	0,8	18,57	19,16	N	0,32	N	0,44	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13622	13622	T	A	MI.22002	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1286	429	L	H	cTc/cAc	0,63	0	0	benign	0,02	neutral	0,4	neutral	0,81	deleterious	-3,19	neutral	-0,81	low_impact	1,78	neutral	0,78	neutral	0,81	deleterious	2,18	17,37	0,23	0,45	disease	0,83	disease	0,69	disease	0,61	disease	0,72	4	neutral	0,59	deleterious	0,69	neutral	-6	neutral	0,28	medium_impact	0,86	medium_impact	0,14	medium_impact	0,42	0,61	0,8	18,57	19,16	N	0,28	N	0,02	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13622	13622	T	C	MI.22003	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1286	429	L	P	cTc/cCc	0,63	0	0	possibly_damaging	0,89	neutral	0,17	neutral	0,8	deleterious	-3,79	deleterious	-3,56	medium_impact	2,58	damaging	0,55	neutral	0,42	deleterious	3,93	23,5	0,18	0,45	disease	0,89	disease	0,86	disease	0,72	disease	0,82	6	neutral	0,94	neutral	0,14	NA	0	deleterious	0,86	low_impact	-1,61	medium_impact	-0,15	medium_impact	1,15	0,59	0,8	18,57	19,16	N	0,28	N	0,83	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13624	13624	A	G	MI.22004	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1288	430	T	A	Acc/Gcc	-5,33	0	0	benign	0,08	neutral	0,4	neutral	0,99	neutral	-1,19	neutral	0,6	neutral_impact	0,16	neutral	0,79	neutral	1	neutral	1,16	11,53	0,57	0,65	neutral	0,39	neutral	0,2	neutral	0,28	neutral	0,37	3	neutral	0,55	deleterious	0,66	neutral	-6	deleterious	0,66	medium_impact	0,26	medium_impact	0,14	low_impact	-1,06	0,52	0,8	17,08	11,57	N	0,38	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13624	13624	A	T	MI.22005	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1288	430	T	S	Acc/Tcc	-5,33	0	0	possibly_damaging	0,73	neutral	0,35	neutral	1,05	neutral	-2,48	neutral	-0,81	low_impact	1,34	neutral	0,79	neutral	0,83	deleterious	2,28	18,01	0,52	0,6	disease	0,69	neutral	0,33	neutral	0,26	disease	0,62	2	neutral	0,76	neutral	0,31	neutral	-3	deleterious	0,72	low_impact	-1,16	medium_impact	0,08	medium_impact	0,02	0,89	0,9	17,08	11,57	N	0,39	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13624	13624	A	C	MI.22006	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1288	430	T	P	Acc/Ccc	-5,33	0	0	probably_damaging	0,96	neutral	0,13	neutral	0,89	deleterious	-4,16	neutral	-1,91	medium_impact	2,72	neutral	0,73	neutral	0,48	deleterious	3,58	23,2	0,17	0,45	disease	0,84	disease	0,83	disease	0,72	disease	0,81	6	deleterious	0,98	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-2,06	medium_impact	-0,22	medium_impact	1,28	0,7	0,85	17,08	11,57	N	0,29	N	0,85	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13625	13625	C	G	MI.22007	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1289	430	T	S	aCc/aGc	0,63	0	0	possibly_damaging	0,73	neutral	0,35	neutral	1,05	neutral	-2,48	neutral	-0,81	low_impact	1,34	neutral	0,79	neutral	0,83	deleterious	2,52	19,59	0,52	0,6	disease	0,69	neutral	0,33	neutral	0,26	disease	0,62	2	neutral	0,76	neutral	0,31	neutral	-3	deleterious	0,72	low_impact	-1,16	medium_impact	0,08	medium_impact	0,02	0,89	0,9	17,08	11,57	N	0,4	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13625	13625	C	A	MI.22008	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1289	430	T	N	aCc/aAc	0,63	0	0	probably_damaging	0,95	neutral	0,19	neutral	0,89	deleterious	-3,33	deleterious	-2,57	medium_impact	2,72	neutral	0,73	neutral	0,6	deleterious	3,81	23,4	0,36	0,5	disease	0,88	disease	0,7	disease	0,56	disease	0,75	5	neutral	0,97	neutral	0,12	deleterious	1	deleterious	0,81	low_impact	-1,96	medium_impact	-0,12	medium_impact	1,28	0,83	0,9	17,08	11,57	N	0,3	N	0,67	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13625	13625	C	T	MI.22009	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1289	430	T	I	aCc/aTc	0,63	0	0	benign	0,16	neutral	0,34	neutral	1	neutral	-1,38	neutral	-1,18	low_impact	1,4	neutral	0,73	neutral	0,73	deleterious	3,04	22,4	0,37	0,5	neutral	0,42	disease	0,56	neutral	0,46	neutral	0,49	0	neutral	0,6	deleterious	0,59	neutral	-6	deleterious	0,7	medium_impact	-0,06	medium_impact	0,07	medium_impact	0,08	0,73	0,85	17,08	11,57	N	0,42	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6058	6058	A	G	MI.2201	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	155	52	H	R	cAc/cGc	5,68	1	0	benign	0,2	deleterious	0	neutral	2,99	neutral	0,95	neutral	-0,1	medium_impact	3,08	damaging	0,56	neutral	0,5	deleterious	2,88	21,8	0,6	0,65	neutral	0,24	disease	0,86	disease	0,67	disease	0,81	6	deleterious	1	neutral	0,4	deleterious	1	neutral	0,39	medium_impact	-0,19	low_impact	-1,48	medium_impact	1,75	0,43	0,9	13,84	68,8	P	0,51	P	0,24	disease_causing	0,86	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13627	13627	C	A	MI.22010	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1291	431	L	M	Cta/Ata	-7,17	0	0	possibly_damaging	0,66	neutral	0,26	neutral	0,97	neutral	-1,06	neutral	-1,37	low_impact	1,45	neutral	0,83	neutral	0,76	deleterious	2,79	21,3	0,33	0,5	disease	0,52	neutral	0,25	neutral	0,21	neutral	0,37	3	neutral	0,78	neutral	0,3	neutral	-3	deleterious	0,69	low_impact	-1,02	medium_impact	-0,02	medium_impact	0,12	0,84	0,9	10,61	12,66	N	0,42	N	0,17	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13627	13627	C	G	MI.22011	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1291	431	L	V	Cta/Gta	-7,17	0	0	possibly_damaging	0,9	neutral	0,57	neutral	0,95	neutral	-0,63	neutral	-2,15	low_impact	1,57	neutral	0,84	neutral	0,9	deleterious	2,32	18,28	0,33	0,5	neutral	0,44	neutral	0,3	neutral	0,19	neutral	0,47	1	neutral	0,88	neutral	0,34	neutral	-3	deleterious	0,69	low_impact	-1,65	medium_impact	0,3	medium_impact	0,23	0,7	0,85	10,61	12,66	N	0,34	N	0,32	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13628	13628	T	A	MI.22012	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1292	431	L	Q	cTa/cAa	-0,98	0	0	probably_damaging	0,99	neutral	0,31	neutral	0,84	neutral	-2,65	deleterious	-4,89	low_impact	1,19	neutral	0,79	neutral	0,79	deleterious	4,18	23,8	0,22	0,45	disease	0,65	neutral	0,29	neutral	0,24	disease	0,58	2	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,74	low_impact	-2,64	medium_impact	0,04	medium_impact	-0,12	0,68	0,85	10,61	12,66	N	0,38	N	0,86	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13628	13628	T	C	MI.22013	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1292	431	L	P	cTa/cCa	-0,98	0	0	probably_damaging	1	neutral	0,23	neutral	0,78	deleterious	-3,51	deleterious	-5,76	medium_impact	2,56	damaging	0,59	neutral	0,5	deleterious	4,01	23,6	0,2	0,45	disease	0,88	disease	0,79	disease	0,59	disease	0,77	5	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,88	low_impact	-3,6	medium_impact	-0,06	medium_impact	1,14	0,61	0,8	10,61	12,66	N	0,28	N	0,95	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13628	13628	T	G	MI.22014	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1292	431	L	R	cTa/cGa	-0,98	0	0	probably_damaging	0,98	neutral	0,43	neutral	0,79	deleterious	-3,01	deleterious	-4,98	medium_impact	3,12	neutral	0,72	neutral	0,45	deleterious	4,26	23,9	0,18	0,45	disease	0,84	disease	0,75	disease	0,55	disease	0,73	5	deleterious	0,98	neutral	0,23	deleterious	1	deleterious	0,85	low_impact	-2,35	medium_impact	0,17	medium_impact	1,65	0,51	0,8	10,61	12,66	N	0,28	N	0,93	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13630	13630	A	C	MI.22015	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1294	432	T	P	Aca/Cca	-5,56	0	0,01	probably_damaging	0,92	neutral	0,23	neutral	0,83	neutral	-2,56	neutral	-1,82	medium_impact	2,35	neutral	0,62	neutral	0,39	deleterious	3,56	23,1	0,19	0,45	disease	0,83	disease	0,74	disease	0,57	disease	0,75	5	neutral	0,94	neutral	0,16	deleterious	1	deleterious	0,82	low_impact	-1,75	medium_impact	-0,06	medium_impact	0,94	0,44	0,8	25,37	21,71	N	0,29	N	0,82	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13630	13630	A	T	MI.22016	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1294	432	T	S	Aca/Tca	-5,56	0	0,01	possibly_damaging	0,52	neutral	0,46	neutral	0,96	neutral	-1,16	neutral	-0,86	low_impact	1,66	neutral	0,82	neutral	0,78	deleterious	2,99	22,2	0,52	0,6	disease	0,65	neutral	0,3	neutral	0,44	disease	0,61	2	neutral	0,55	deleterious	0,47	neutral	-3	deleterious	0,51	medium_impact	-0,78	medium_impact	0,19	medium_impact	0,31	0,59	0,8	25,37	21,71	N	0,34	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13630	13630	A	G	MI.22017	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1294	432	T	A	Aca/Gca	-5,56	0	0,01	benign	0,05	neutral	0,54	neutral	0,9	neutral	-0,93	neutral	-0,3	low_impact	1,54	neutral	0,78	neutral	0,82	deleterious	1,93	15,76	0,65	0,7	disease	0,6	neutral	0,25	disease	0,58	disease	0,58	2	neutral	0,4	deleterious	0,75	neutral	-6	neutral	0,41	medium_impact	0,47	medium_impact	0,27	medium_impact	0,2	0,3	0,8	25,37	21,71	N	0,3	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13631	13631	C	A	MI.22018	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1295	432	T	K	aCa/aAa	-0,29	0	0	possibly_damaging	0,73	neutral	0,32	neutral	0,84	neutral	-2,15	neutral	-0,92	medium_impact	2,35	neutral	0,72	neutral	0,53	deleterious	4,25	23,9	0,31	0,45	disease	0,83	disease	0,61	disease	0,7	disease	0,76	5	neutral	0,78	neutral	0,3	NA	0	deleterious	0,66	low_impact	-1,16	medium_impact	0,05	medium_impact	0,94	0,61	0,8	25,37	21,71	N	0,31	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13631	13631	C	T	MI.22019	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1295	432	T	M	aCa/aTa	-0,29	0	0	benign	0,2	neutral	0,3	neutral	0,97	neutral	-1,12	neutral	2,55	neutral_impact	0,2	neutral	0,76	neutral	0,91	neutral	-0,47	0,27	0,42	0,55	neutral	0,43	neutral	0,06	neutral	0,18	neutral	0,24	5	neutral	0,64	deleterious	0,55	neutral	-6	neutral	0,19	medium_impact	-0,17	medium_impact	0,03	low_impact	-1,02	0,61	0,8	25,37	21,71	N	0,53	P	0,17	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6059	6059	C	G	MI.2202	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	156	52	H	Q	caC/caG	8,69	1	0	benign	0,02	neutral	1	neutral	3,13	neutral	1,57	neutral	2,07	neutral_impact	-1,75	neutral	0,71	neutral	0,91	deleterious	0,71	8,88	0,58	0,65	neutral	0,29	neutral	0,12	neutral	0,33	neutral	0,23	5	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,14	medium_impact	0,83	high_impact	1,86	low_impact	-2,72	0,65	0,9	13,84	68,8	P	0,55	P	0	disease_causing	0,66	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13633	13633	G	T	MI.22020	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1297	433	G	C	Ggt/Tgt	-0,52	0	0	probably_damaging	0,99	neutral	0,18	neutral	0,65	deleterious	-7,14	deleterious	-5,68	medium_impact	3,21	neutral	0,69	neutral	0,3	deleterious	4,26	23,9	0,27	0,45	disease	0,97	disease	0,83	disease	0,65	disease	0,84	7	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,85	low_impact	-2,64	medium_impact	-0,13	medium_impact	1,73	0,39	0,8	23,55	15,58	N	0,27	N	0,76	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13633	13633	G	A	MI.22021	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1297	433	G	S	Ggt/Agt	-0,52	0	0	benign	0,42	neutral	0,43	neutral	0,79	deleterious	-3,53	deleterious	-2,63	medium_impact	2,17	neutral	0,81	neutral	0,81	deleterious	2,32	18,29	0,4	0,5	disease	0,71	disease	0,58	neutral	0,39	disease	0,5	0	neutral	0,52	deleterious	0,51	neutral	-3	neutral	0,29	medium_impact	-0,61	medium_impact	0,17	medium_impact	0,78	0,78	0,85	23,55	15,58	N	0,3	N	0,08	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13633	13633	G	C	MI.22022	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1297	433	G	R	Ggt/Cgt	-0,52	0	0	probably_damaging	0,97	neutral	0,36	neutral	0,72	deleterious	-3,89	deleterious	-4,46	medium_impact	2,86	neutral	0,71	neutral	0,36	deleterious	4	23,6	0,3	0,45	disease	0,74	disease	0,82	disease	0,74	disease	0,77	5	neutral	0,97	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-2,18	medium_impact	0,1	medium_impact	1,41	0,79	0,85	23,55	15,58	N	0,27	N	0,81	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13634	13634	G	A	MI.22023	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1298	433	G	D	gGt/gAt	-0,06	0	0	probably_damaging	0,91	neutral	0,23	neutral	0,71	deleterious	-3,7	deleterious	-3,18	medium_impact	2,31	neutral	0,81	neutral	0,54	deleterious	3,61	23,2	0,32	0,5	disease	0,68	disease	0,79	disease	0,76	disease	0,75	5	neutral	0,94	neutral	0,16	deleterious	1	deleterious	0,66	low_impact	-1,7	medium_impact	-0,06	medium_impact	0,91	0,43	0,8	23,55	15,58	N	0,31	N	0,69	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13634	13634	G	C	MI.22024	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1298	433	G	A	gGt/gCt	-0,06	0	0	possibly_damaging	0,86	neutral	0,53	neutral	0,73	deleterious	-3,2	deleterious	-3,45	medium_impact	2,51	neutral	0,77	neutral	0,62	deleterious	2,86	21,7	0,45	0,55	disease	0,69	disease	0,51	disease	0,51	neutral	0,48	0	neutral	0,84	neutral	0,34	NA	0	deleterious	0,56	low_impact	-1,5	medium_impact	0,26	medium_impact	1,09	0,71	0,85	23,55	15,58	N	0,25	N	0,42	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13634	13634	G	T	MI.22025	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1298	433	G	V	gGt/gTt	-0,06	0	0	probably_damaging	0,97	neutral	0,52	neutral	0,68	deleterious	-4,57	deleterious	-5,64	medium_impact	2,86	neutral	0,74	neutral	0,36	deleterious	3,78	23,4	0,27	0,45	disease	0,83	disease	0,75	disease	0,67	disease	0,73	5	neutral	0,97	neutral	0,28	deleterious	1	deleterious	0,79	low_impact	-2,18	medium_impact	0,25	medium_impact	1,41	0,43	0,8	23,55	15,58	N	0,23	N	0,78	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13636	13636	C	G	MI.22026	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1300	434	Q	E	Caa/Gaa	-6,02	0	0	benign	0,18	neutral	0,29	neutral	1,03	neutral	1,16	neutral	-1,89	medium_impact	2,29	neutral	0,85	neutral	0,72	deleterious	0,2	4,69	0,6	0,65	neutral	0,3	neutral	0,44	neutral	0,47	neutral	0,46	1	neutral	0,66	deleterious	0,56	neutral	-3	neutral	0,24	medium_impact	-0,12	medium_impact	0,02	medium_impact	0,89	0,61	0,8	25,54	16,4	N	0,38	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13636	13636	C	A	MI.22027	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1300	434	Q	K	Caa/Aaa	-6,02	0	0	benign	0,01	neutral	0,31	neutral	1,01	neutral	1,03	neutral	-2,09	low_impact	1,84	neutral	0,85	neutral	0,79	deleterious	0,74	9,06	0,64	0,7	neutral	0,29	neutral	0,49	neutral	0,47	neutral	0,46	1	neutral	0,68	deleterious	0,65	neutral	-6	neutral	0,16	medium_impact	1,15	medium_impact	0,04	medium_impact	0,48	0,51	0,8	25,54	16,4	N	0,34	N	0,13	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13637	13637	A	G	MI.22028	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1301	434	Q	R	cAa/cGa	-0,98	0	0,02	benign	0,01	neutral	0,36	neutral	0,95	neutral	-0,15	neutral	-2,38	low_impact	1,49	neutral	0,82	neutral	0,65	deleterious	0,58	8,02	0,63	0,7	neutral	0,38	disease	0,51	neutral	0,48	neutral	0,47	1	neutral	0,63	deleterious	0,68	neutral	-6	neutral	0,19	medium_impact	1,15	medium_impact	0,1	medium_impact	0,16	0,44	0,8	25,54	16,4	N	0,37	N	0,34	disease_causing_automatic	0	0,06	rs200855215	Pathogenic	Leber's_optic_atrophy	RCV000055699.1	MedGen:OMIM:SNOMED_CT	.	.	.	.	A13637G	Possible LHON factor	+	-	Reported	2
chrM	13637	13637	A	C	MI.22029	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1301	434	Q	P	cAa/cCa	-0,98	0	0,02	benign	0,01	neutral	0,23	neutral	0,94	neutral	-0,65	deleterious	-4,14	low_impact	1,49	neutral	0,85	neutral	0,59	deleterious	2,11	16,93	0,24	0,45	disease	0,57	disease	0,76	neutral	0,35	disease	0,57	1	neutral	0,77	deleterious	0,61	neutral	-6	deleterious	0,65	medium_impact	1,15	medium_impact	-0,06	medium_impact	0,16	0,4	0,8	25,54	16,4	N	0,32	N	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6059	6059	C	A	MI.2203	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	156	52	H	Q	caC/caA	8,69	1	0	benign	0,02	neutral	1	neutral	3,13	neutral	1,57	neutral	2,07	neutral_impact	-1,75	neutral	0,71	neutral	0,91	neutral	1,11	11,27	0,58	0,65	neutral	0,29	neutral	0,12	neutral	0,33	neutral	0,23	5	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,14	medium_impact	0,83	high_impact	1,86	low_impact	-2,72	0,65	0,9	13,84	68,8	P	0,55	P	0	disease_causing	0,66	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13637	13637	A	T	MI.22030	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1301	434	Q	L	cAa/cTa	-0,98	0	0,02	benign	0,18	neutral	0,69	neutral	0,93	neutral	-1,96	deleterious	-4,89	medium_impact	2,09	neutral	0,8	neutral	0,57	deleterious	2,23	17,72	0,42	0,5	disease	0,63	disease	0,53	neutral	0,37	disease	0,51	0	neutral	0,19	deleterious	0,76	neutral	-3	neutral	0,42	medium_impact	-0,12	medium_impact	0,42	medium_impact	0,71	0,32	0,8	25,54	16,4	N	0,24	N	0,74	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13638	13638	A	C	MI.22031	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1302	434	Q	H	caA/caC	0,17	0	0	benign	0,01	neutral	0,54	neutral	0,96	neutral	-1,9	deleterious	-2,76	neutral_impact	0,47	neutral	0,81	neutral	0,8	deleterious	2,16	17,22	0,59	0,65	neutral	0,46	neutral	0,18	neutral	0,23	neutral	0,26	5	neutral	0,44	deleterious	0,77	neutral	-6	deleterious	0,63	medium_impact	1,15	medium_impact	0,27	medium_impact	-0,77	0,49	0,8	25,54	16,4	N	0,32	N	0,48	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13638	13638	A	T	MI.22032	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1302	434	Q	H	caA/caT	0,17	0	0	benign	0,01	neutral	0,54	neutral	0,96	neutral	-1,9	deleterious	-2,76	neutral_impact	0,47	neutral	0,81	neutral	0,8	deleterious	2,32	18,28	0,59	0,65	neutral	0,46	neutral	0,18	neutral	0,23	neutral	0,26	5	neutral	0,44	deleterious	0,77	neutral	-6	deleterious	0,63	medium_impact	1,15	medium_impact	0,27	medium_impact	-0,77	0,49	0,8	25,54	16,4	N	0,32	N	0,48	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13639	13639	C	A	MI.22033	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1303	435	P	T	Cct/Act	-2,35	0	0	probably_damaging	1	neutral	0,41	neutral	0,83	neutral	-2,46	deleterious	-7,19	medium_impact	2,2	neutral	0,75	neutral	0,29	deleterious	4	23,6	0,51	0,6	disease	0,67	disease	0,61	disease	0,55	neutral	0,49	0	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,15	medium_impact	0,81	0,8	0,85	27,69	7,3	N	0,25	N	0,91	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13639	13639	C	T	MI.22034	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1303	435	P	S	Cct/Tct	-2,35	0	0	probably_damaging	1	neutral	0,46	neutral	0,82	neutral	-2,42	deleterious	-7,19	medium_impact	3	neutral	0,73	damaging	0,15	deleterious	4,01	23,6	0,58	0,65	disease	0,67	disease	0,69	disease	0,56	disease	0,55	1	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,19	medium_impact	1,54	0,35	0,8	27,69	7,3	N	0,25	N	0,78	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13639	13639	C	G	MI.22035	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1303	435	P	A	Cct/Gct	-2,35	0	0	probably_damaging	1	neutral	0,52	neutral	0,82	neutral	-2,27	deleterious	-7,19	medium_impact	3,26	neutral	0,71	damaging	0,2	deleterious	3,21	22,7	0,51	0,6	disease	0,68	disease	0,55	disease	0,63	disease	0,56	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,25	medium_impact	1,78	0,85	0,9	27,69	7,3	N	0,26	N	0,73	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13640	13640	C	A	MI.22036	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1304	435	P	H	cCt/cAt	4,29	0,98	0	probably_damaging	1	neutral	0,54	neutral	0,78	deleterious	-4,15	deleterious	-8,09	high_impact	3,81	neutral	0,72	damaging	0,11	deleterious	4,24	23,9	0,53	0,6	disease	0,81	disease	0,82	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,27	high_impact	2,28	0,56	0,8	27,69	7,3	N	0,46	N	0,72	disease_causing	0,89	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13640	13640	C	G	MI.22037	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1304	435	P	R	cCt/cGt	4,29	0,98	0	probably_damaging	1	neutral	0,36	neutral	0,77	neutral	-2,77	deleterious	-8,08	high_impact	3,81	neutral	0,69	damaging	0,11	deleterious	3,74	23,3	0,47	0,55	disease	0,64	disease	0,86	disease	0,7	disease	0,77	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,1	high_impact	2,28	0,68	0,85	27,69	7,3	N	0,49	N	0,64	disease_causing	0,94	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13640	13640	C	T	MI.22038	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1304	435	P	L	cCt/cTt	4,29	0,98	0	probably_damaging	1	neutral	0,71	neutral	0,88	neutral	-2,83	deleterious	-8,98	medium_impact	3,46	neutral	0,7	damaging	0,1	deleterious	4,46	24,2	0,52	0,6	disease	0,52	disease	0,81	disease	0,6	disease	0,68	4	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,45	medium_impact	1,96	0,84	0,9	27,69	7,3	N	0,41	N	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13642	13642	C	A	MI.22039	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1306	436	R	S	Cgc/Agc	-11,75	0	0	possibly_damaging	0,82	neutral	0,44	neutral	0,87	neutral	-2,23	deleterious	-4,84	high_impact	3,83	neutral	0,69	neutral	0,29	deleterious	3,1	22,5	0,52	0,6	disease	0,62	disease	0,79	disease	0,71	disease	0,71	4	neutral	0,81	neutral	0,31	deleterious	1	deleterious	0,55	low_impact	-1,37	medium_impact	0,18	high_impact	2,3	0,57	0,8	11,61	7,34	N	0,32	N	0,81	polymorphism	0,63	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6060	6060	A	G	MI.2204	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	157	53	I	V	Atc/Gtc	-1,72	0	0	benign	0	neutral	0,28	neutral	2,86	neutral	-0,18	neutral	-0,47	medium_impact	2,14	neutral	0,7	neutral	0,84	neutral	-0,22	0,98	0,64	0,65	neutral	0,29	neutral	0,43	neutral	0,28	neutral	0,47	1	neutral	0,72	deleterious	0,64	neutral	-3	neutral	0,16	high_impact	2,07	medium_impact	-0,04	medium_impact	0,88	0,65	0,9	8,97	39,65	N	0,54	P	0,23	disease_causing	0,86	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13642	13642	C	G	MI.22040	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1306	436	R	G	Cgc/Ggc	-11,75	0	0	possibly_damaging	0,86	neutral	0,35	neutral	0,82	deleterious	-3,43	deleterious	-5,75	high_impact	3,83	neutral	0,66	neutral	0,35	deleterious	2,79	21,3	0,59	0,65	disease	0,82	disease	0,74	disease	0,72	disease	0,75	5	neutral	0,87	neutral	0,25	deleterious	1	deleterious	0,56	low_impact	-1,5	medium_impact	0,08	high_impact	2,3	0,54	0,8	11,61	7,34	N	0,31	N	0,93	polymorphism	0,64	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13642	13642	C	T	MI.22041	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1306	436	R	C	Cgc/Tgc	-11,75	0	0	probably_damaging	0,98	neutral	0,18	neutral	0,75	deleterious	-6,42	deleterious	-6,71	high_impact	3,83	neutral	0,7	damaging	0,18	deleterious	5,11	25,3	0,41	0,5	disease	0,97	disease	0,85	disease	0,76	disease	0,85	7	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-2,35	medium_impact	-0,13	high_impact	2,3	0,81	0,85	11,61	7,34	N	0,31	N	1	disease_causing	0,99	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13643	13643	G	A	MI.22042	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1307	436	R	H	cGc/cAc	2,23	0,95	0	benign	0,11	neutral	0,54	neutral	0,78	deleterious	-3,72	deleterious	-3,51	medium_impact	3,13	neutral	0,65	neutral	0,33	deleterious	2,56	19,88	0,64	0,7	disease	0,88	disease	0,78	disease	0,63	disease	0,7	4	neutral	0,37	deleterious	0,72	neutral	-3	neutral	0,31	medium_impact	0,12	medium_impact	0,27	medium_impact	1,66	0,86	0,9	11,61	7,34	N	0,38	N	0,43	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13643	13643	G	C	MI.22043	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1307	436	R	P	cGc/cCc	2,23	0,95	0	probably_damaging	0,96	neutral	0,23	neutral	0,77	deleterious	-3,78	deleterious	-5,82	high_impact	3,83	neutral	0,71	damaging	0,21	deleterious	4,23	23,9	0,44	0,55	disease	0,75	disease	0,88	disease	0,71	disease	0,77	5	neutral	0,97	neutral	0,14	deleterious	2	deleterious	0,81	low_impact	-2,06	medium_impact	-0,06	high_impact	2,3	0,54	0,8	11,61	7,34	N	0,45	N	0,98	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13643	13643	G	T	MI.22044	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1307	436	R	L	cGc/cTc	2,23	0,95	0	benign	0,08	neutral	0,66	neutral	0,79	deleterious	-3,73	deleterious	-5,92	medium_impact	3,02	neutral	0,65	neutral	0,31	deleterious	2,52	19,6	0,56	0,6	disease	0,83	disease	0,89	disease	0,72	disease	0,79	6	neutral	0,25	deleterious	0,79	neutral	-3	neutral	0,32	medium_impact	0,26	medium_impact	0,39	medium_impact	1,56	0,55	0,8	11,61	7,34	N	0,36	N	0,99	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13645	13645	T	A	MI.22045	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1309	437	F	I	Ttc/Atc	-3,73	0	0	possibly_damaging	0,63	neutral	0,4	neutral	0,9	neutral	-0,88	deleterious	-4,51	medium_impact	1,94	neutral	0,79	neutral	0,76	deleterious	2,86	21,7	0,49	0,55	disease	0,75	disease	0,53	neutral	0,39	disease	0,53	1	neutral	0,66	neutral	0,39	NA	0	neutral	0,41	medium_impact	-0,97	medium_impact	0,14	medium_impact	0,57	0,51	0,8	5,64	8,73	N	0,31	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13645	13645	T	C	MI.22046	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1309	437	F	L	Ttc/Ctc	-3,73	0	0	benign	0,08	neutral	0,66	neutral	0,97	neutral	-0,2	deleterious	-4,49	medium_impact	2,29	neutral	0,8	neutral	0,7	deleterious	2,29	18,09	0,59	0,65	disease	0,54	disease	0,6	neutral	0,4	neutral	0,49	0	neutral	0,25	deleterious	0,79	neutral	-3	neutral	0,18	medium_impact	0,26	medium_impact	0,39	medium_impact	0,89	0,44	0,8	5,64	8,73	N	0,24	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13645	13645	T	G	MI.22047	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1309	437	F	V	Ttc/Gtc	-3,73	0	0	possibly_damaging	0,74	neutral	0,51	neutral	0,89	neutral	-1,07	deleterious	-5,13	medium_impact	3,27	neutral	0,82	neutral	0,61	deleterious	2,64	20,5	0,45	0,55	disease	0,73	disease	0,68	disease	0,62	disease	0,65	3	neutral	0,72	neutral	0,39	NA	0	deleterious	0,45	low_impact	-1,18	medium_impact	0,24	medium_impact	1,78	0,34	0,8	5,64	8,73	N	0,29	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13646	13646	T	C	MI.22048	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1310	437	F	S	tTc/tCc	1,77	0,02	0	probably_damaging	0,96	neutral	0,42	neutral	0,88	neutral	-1,23	deleterious	-5,31	low_impact	1,66	neutral	0,86	neutral	0,92	deleterious	3,15	22,6	0,5	0,6	neutral	0,43	disease	0,65	neutral	0,44	neutral	0,5	0	neutral	0,96	neutral	0,23	neutral	-2	deleterious	0,64	low_impact	-2,06	medium_impact	0,16	medium_impact	0,31	0,28	0,8	5,64	8,73	N	0,34	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13646	13646	T	A	MI.22049	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1310	437	F	Y	tTc/tAc	1,77	0,02	0	possibly_damaging	0,89	neutral	1	neutral	0,85	neutral	-1,74	neutral	-1,3	low_impact	1,32	neutral	0,86	neutral	0,97	deleterious	3,01	22,3	0,57	0,65	disease	0,68	disease	0,52	neutral	0,37	disease	0,5	0	neutral	0,89	deleterious	0,56	neutral	-3	deleterious	0,62	low_impact	-1,61	high_impact	1,89	medium_impact	0	0,55	0,8	5,64	8,73	N	0,26	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6060	6060	A	C	MI.2205	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	157	53	I	L	Atc/Ctc	-1,72	0	0	benign	0,07	neutral	0,39	neutral	2,87	neutral	2,54	neutral	-0,61	neutral_impact	0,53	neutral	0,66	neutral	0,82	deleterious	0,18	4,42	0,48	0,55	neutral	0,15	neutral	0,25	neutral	0,18	neutral	0,43	1	neutral	0,57	deleterious	0,66	neutral	-6	neutral	0,14	medium_impact	0,3	medium_impact	0,09	medium_impact	-0,61	0,78	0,9	8,97	39,65	P	0,55	P	0,61	disease_causing	0,94	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13646	13646	T	G	MI.22050	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1310	437	F	C	tTc/tGc	1,77	0,02	0	probably_damaging	0,98	neutral	0,18	neutral	0,86	neutral	-1,58	deleterious	-5,84	medium_impact	2,71	neutral	0,78	neutral	0,45	deleterious	4,21	23,9	0,48	0,55	disease	0,77	disease	0,82	disease	0,55	disease	0,72	4	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,76	low_impact	-2,35	medium_impact	-0,13	medium_impact	1,27	0,28	0,8	5,64	8,73	N	0,3	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13647	13647	C	G	MI.22051	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1311	437	F	L	ttC/ttG	-1,67	0	0	benign	0,08	neutral	0,66	neutral	0,97	neutral	-0,2	deleterious	-4,49	medium_impact	2,29	neutral	0,8	neutral	0,7	deleterious	2,6	20,2	0,59	0,65	disease	0,54	disease	0,6	neutral	0,4	neutral	0,49	0	neutral	0,25	deleterious	0,79	neutral	-3	neutral	0,18	medium_impact	0,26	medium_impact	0,39	medium_impact	0,89	0,44	0,8	5,64	8,73	N	0,24	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13647	13647	C	A	MI.22052	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1311	437	F	L	ttC/ttA	-1,67	0	0	benign	0,08	neutral	0,66	neutral	0,97	neutral	-0,2	deleterious	-4,49	medium_impact	2,29	neutral	0,8	neutral	0,7	deleterious	2,88	21,7	0,59	0,65	disease	0,54	disease	0,6	neutral	0,4	neutral	0,49	0	neutral	0,25	deleterious	0,79	neutral	-3	neutral	0,18	medium_impact	0,26	medium_impact	0,39	medium_impact	0,89	0,44	0,8	5,64	8,73	N	0,24	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13648	13648	C	T	MI.22053	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1312	438	P	S	Ccc/Tcc	-5,79	0	0	benign	0,04	neutral	0,46	neutral	1,1	neutral	-0,57	neutral	-1,53	neutral_impact	-0,16	neutral	0,91	neutral	0,99	deleterious	2,35	18,51	0,59	0,65	disease	0,51	neutral	0,14	neutral	0,22	neutral	0,24	5	neutral	0,51	deleterious	0,71	neutral	-6	deleterious	0,66	medium_impact	0,57	medium_impact	0,19	low_impact	-1,35	0,2	0,8	21,06	13,62	N	0,41	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13648	13648	C	G	MI.22054	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1312	438	P	A	Ccc/Gcc	-5,79	0	0	possibly_damaging	0,45	neutral	0,51	neutral	1,01	neutral	-0,64	neutral	-2,24	low_impact	1,33	neutral	0,84	neutral	0,78	neutral	1,38	12,67	0,46	0,55	neutral	0,46	neutral	0,1	neutral	0,36	neutral	0,3	4	neutral	0,46	deleterious	0,53	neutral	-3	deleterious	0,66	medium_impact	-0,66	medium_impact	0,24	medium_impact	0,01	0,68	0,85	21,06	13,62	N	0,33	N	0,72	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13648	13648	C	A	MI.22055	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1312	438	P	T	Ccc/Acc	-5,79	0	0	benign	0,07	neutral	0,41	neutral	0,97	neutral	-1,19	neutral	-1,44	neutral_impact	0,06	neutral	0,86	neutral	0,91	deleterious	2,16	17,27	0,45	0,55	disease	0,57	neutral	0,15	neutral	0,23	neutral	0,37	3	neutral	0,54	deleterious	0,67	neutral	-6	deleterious	0,66	medium_impact	0,32	medium_impact	0,15	low_impact	-1,15	0,65	0,8	21,06	13,62	N	0,35	N	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13649	13649	C	G	MI.22056	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1313	438	P	R	cCc/cGc	-2,58	0	0	possibly_damaging	0,82	neutral	0,35	neutral	0,96	neutral	-1,19	deleterious	-2,63	medium_impact	2,13	neutral	0,78	neutral	0,59	deleterious	2,15	17,19	0,5	0,6	disease	0,56	neutral	0,33	disease	0,51	disease	0,59	2	neutral	0,84	neutral	0,27	NA	0	deleterious	0,71	low_impact	-1,37	medium_impact	0,08	medium_impact	0,74	0,55	0,8	21,06	13,62	N	0,31	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13649	13649	C	A	MI.22057	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1313	438	P	H	cCc/cAc	-2,58	0	0	probably_damaging	0,97	neutral	0,54	neutral	0,93	neutral	-1,78	neutral	-2,24	low_impact	1,24	neutral	0,86	neutral	0,86	deleterious	2,27	17,95	0,5	0,6	disease	0,8	neutral	0,26	neutral	0,31	disease	0,59	2	neutral	0,96	neutral	0,29	neutral	-2	deleterious	0,71	low_impact	-2,18	medium_impact	0,27	medium_impact	-0,07	0,52	0,8	21,06	13,62	N	0,26	N	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13649	13649	C	T	MI.22058	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1313	438	P	L	cCc/cTc	-2,58	0	0	benign	0,33	neutral	0,74	neutral	1,04	neutral	-1,87	deleterious	-3,42	neutral_impact	-0,12	neutral	0,81	neutral	0,95	deleterious	2,42	18,94	0,54	0,6	disease	0,69	neutral	0,15	neutral	0,26	neutral	0,36	3	neutral	0,23	deleterious	0,71	neutral	-6	deleterious	0,69	medium_impact	-0,45	medium_impact	0,48	low_impact	-1,31	0,84	0,9	21,06	13,62	N	0,24	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13651	13651	A	G	MI.22059	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1315	439	T	A	Acc/Gcc	-20	0	0,04	benign	0,08	neutral	0,52	neutral	1	neutral	-0,02	neutral	-1,55	neutral_impact	0,79	neutral	0,88	neutral	0,95	deleterious	2,92	21,9	0,69	0,75	neutral	0,46	neutral	0,12	neutral	0,26	neutral	0,31	4	neutral	0,41	deleterious	0,72	neutral	-6	deleterious	0,69	medium_impact	0,26	medium_impact	0,25	medium_impact	-0,48	0,3	0,8	7,79	12	N	0,43	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6060	6060	A	T	MI.2206	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	157	53	I	F	Atc/Ttc	-1,72	0	0	possibly_damaging	0,55	neutral	0,11	neutral	2,78	neutral	-1,25	neutral	-1,94	medium_impact	2,08	neutral	0,61	neutral	0,39	neutral	1,78	14,86	0,47	0,55	neutral	0,47	disease	0,77	neutral	0,27	neutral	0,5	0	neutral	0,88	neutral	0,28	NA	0	deleterious	0,57	medium_impact	-0,84	medium_impact	-0,31	medium_impact	0,82	0,81	0,9	8,97	39,65	N	0,39	N	0,85	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13651	13651	A	C	MI.22060	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1315	439	T	P	Acc/Ccc	-20	0	0,04	probably_damaging	0,95	neutral	0,22	neutral	1,05	neutral	0,51	neutral	0,2	neutral_impact	-1,06	neutral	0,83	neutral	0,99	neutral	1,47	13,15	0,57	0,65	neutral	0,43	neutral	0,1	neutral	0,14	neutral	0,29	4	neutral	0,97	neutral	0,14	neutral	-2	deleterious	0,68	low_impact	-1,96	medium_impact	-0,07	low_impact	-2,17	0,68	0,85	7,79	12	N	0,51	P	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13651	13651	A	T	MI.22061	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1315	439	T	S	Acc/Tcc	-20	0	0,04	benign	0,12	neutral	0,42	neutral	1,22	neutral	1,59	neutral	-0,99	neutral_impact	-0,24	neutral	0,88	neutral	0,98	deleterious	2,54	19,75	0,71	0,75	neutral	0,46	neutral	0,1	neutral	0,2	neutral	0,32	4	neutral	0,51	deleterious	0,65	neutral	-6	deleterious	0,67	medium_impact	0,08	medium_impact	0,16	low_impact	-1,42	0,65	0,8	7,79	12	N	0,52	P	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13652	13652	C	A	MI.22062	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1316	439	T	N	aCc/aAc	-9,46	0	0	possibly_damaging	0,82	neutral	0,31	neutral	0,94	neutral	-1,11	neutral	-2,25	low_impact	1,68	neutral	0,84	neutral	0,56	deleterious	3,84	23,4	0,75	0,8	disease	0,54	neutral	0,4	disease	0,52	disease	0,63	3	neutral	0,85	neutral	0,25	neutral	-3	deleterious	0,72	low_impact	-1,37	medium_impact	0,04	medium_impact	0,33	0,76	0,85	7,79	12	N	0,32	N	0,39	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13652	13652	C	G	MI.22063	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1316	439	T	S	aCc/aGc	-9,46	0	0	benign	0,12	neutral	0,42	neutral	1,22	neutral	1,59	neutral	-0,99	neutral_impact	-0,24	neutral	0,88	neutral	0,98	deleterious	2,21	17,59	0,71	0,75	neutral	0,46	neutral	0,1	neutral	0,2	neutral	0,32	4	neutral	0,51	deleterious	0,65	neutral	-6	deleterious	0,67	medium_impact	0,08	medium_impact	0,16	low_impact	-1,42	0,65	0,8	7,79	12	N	0,49	N	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13652	13652	C	T	MI.22064	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1316	439	T	I	aCc/aTc	-9,46	0	0	probably_damaging	0,91	neutral	0,41	neutral	0,92	neutral	-1,67	deleterious	-3,04	medium_impact	2,23	neutral	0,84	neutral	0,54	deleterious	4,15	23,8	0,7	0,75	disease	0,63	neutral	0,29	disease	0,52	disease	0,6	2	neutral	0,91	neutral	0,25	deleterious	1	deleterious	0,73	low_impact	-1,7	medium_impact	0,15	medium_impact	0,83	0,42	0,8	7,79	12	N	0,31	N	0,59	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13654	13654	C	G	MI.22065	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1318	440	L	V	Ctt/Gtt	-7,17	0	0	benign	0,36	neutral	0,51	neutral	0,8	neutral	-1,34	neutral	-1,15	low_impact	1,89	neutral	0,82	neutral	0,96	neutral	0,91	10,12	0,65	0,7	NA	NA	neutral	0,28	neutral	0,45	neutral	0,19	6	neutral	0,41	deleterious	0,58	neutral	-6	neutral	0,32	medium_impact	-0,51	medium_impact	0,24	medium_impact	0,52	0,72	0,85	14,43	13,06	N	0,36	N	0,21	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13654	13654	C	A	MI.22066	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1318	440	L	I	Ctt/Att	-7,17	0	0	possibly_damaging	0,48	neutral	0,42	neutral	0,81	neutral	-1,22	neutral	-0,84	low_impact	1	neutral	0,81	neutral	0,98	neutral	1,57	13,67	0,58	0,65	NA	NA	neutral	0,17	neutral	0,26	neutral	0,23	5	neutral	0,55	deleterious	0,47	neutral	-3	neutral	0,39	medium_impact	-0,71	medium_impact	0,16	medium_impact	-0,29	0,76	0,85	14,43	13,06	N	0,41	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13654	13654	C	T	MI.22067	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1318	440	L	F	Ctt/Ttt	-7,17	0	0	benign	0,04	neutral	0,76	neutral	0,79	neutral	-1,43	neutral	-2,34	medium_impact	2,02	neutral	0,79	neutral	0,8	neutral	1,08	11,13	0,62	0,65	NA	NA	neutral	0,34	neutral	0,32	neutral	0,17	7	neutral	0,17	deleterious	0,86	neutral	-3	neutral	0,15	medium_impact	0,57	medium_impact	0,51	medium_impact	0,64	0,56	0,8	14,43	13,06	N	0,27	N	0,29	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13655	13655	T	C	MI.22068	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1319	440	L	P	cTt/cCt	-2,81	0	0	benign	0,03	neutral	0,24	neutral	0,69	deleterious	-3,32	deleterious	-3,07	medium_impact	2,1	neutral	0,83	neutral	0,57	deleterious	2,02	16,37	0,49	0,55	NA	NA	disease	0,75	disease	0,56	disease	0,64	3	neutral	0,75	deleterious	0,61	neutral	-3	neutral	0,26	medium_impact	0,69	medium_impact	-0,04	medium_impact	0,72	0,46	0,8	14,43	13,06	N	0,33	N	0,18	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13655	13655	T	A	MI.22069	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1319	440	L	H	cTt/cAt	-2,81	0	0	probably_damaging	0,95	neutral	0,56	neutral	0,67	deleterious	-4,07	deleterious	-3,8	medium_impact	1,95	neutral	0,79	neutral	0,65	deleterious	4,15	23,8	0,4	0,5	NA	NA	disease	0,62	neutral	0,38	neutral	0,48	0	neutral	0,95	neutral	0,31	deleterious	1	deleterious	0,76	low_impact	-1,96	medium_impact	0,29	medium_impact	0,58	0,53	0,8	14,43	13,06	N	0,21	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6061	6061	T	A	MI.2207	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	158	53	I	N	aTc/aAc	4,75	1	0	probably_damaging	0,94	deleterious	0	neutral	2,76	neutral	-1,92	deleterious	-3,65	high_impact	4,05	neutral	0,61	neutral	0,41	deleterious	3,99	23,6	0,21	0,55	neutral	0,41	disease	0,85	disease	0,6	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,76	low_impact	-1,88	low_impact	-1,48	high_impact	2,64	0,76	0,9	8,97	39,65	P	0,49	N	0,94	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13655	13655	T	G	MI.22070	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1319	440	L	R	cTt/cGt	-2,81	0	0	possibly_damaging	0,83	neutral	0,37	neutral	0,68	deleterious	-3,92	deleterious	-3,1	medium_impact	2,44	neutral	0,72	neutral	0,39	deleterious	4,29	24	0,44	0,55	NA	NA	disease	0,71	disease	0,66	disease	0,67	3	neutral	0,84	neutral	0,27	NA	0	deleterious	0,77	low_impact	-1,4	medium_impact	0,11	medium_impact	1,03	0,65	0,8	14,43	13,06	N	0,28	N	0,57	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13657	13657	A	G	MI.22071	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1321	441	T	A	Act/Gct	-9,69	0	0	benign	0,01	neutral	0,55	neutral	1,01	neutral	0,21	neutral	-0,74	neutral_impact	0,3	neutral	0,87	neutral	0,87	neutral	-0,26	0,82	0,61	0,65	neutral	0,43	neutral	0,11	neutral	0,38	neutral	0,33	3	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,11	medium_impact	1,15	medium_impact	0,28	medium_impact	-0,93	0,35	0,8	24,54	14,03	N	0,39	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13657	13657	A	T	MI.22072	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1321	441	T	S	Act/Tct	-9,69	0	0	benign	0,27	neutral	0,46	neutral	1,11	neutral	-0,29	neutral	-1,03	neutral_impact	-0,76	neutral	0,81	neutral	0,94	neutral	-0,99	0,02	0,68	0,7	neutral	0,38	neutral	0,03	neutral	0,15	neutral	0,2	6	neutral	0,45	deleterious	0,6	neutral	-6	neutral	0,26	medium_impact	-0,34	medium_impact	0,19	low_impact	-1,9	0,71	0,85	24,54	14,03	N	0,51	P	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13657	13657	A	C	MI.22073	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1321	441	T	P	Act/Cct	-9,69	0	0	possibly_damaging	0,66	neutral	0,24	neutral	0,93	neutral	-1,26	neutral	-2,1	neutral_impact	0,6	neutral	0,82	neutral	0,83	deleterious	2,02	16,35	0,43	0,55	neutral	0,5	neutral	0,45	neutral	0,22	neutral	0,42	2	neutral	0,79	neutral	0,29	neutral	-3	deleterious	0,64	low_impact	-1,02	medium_impact	-0,04	medium_impact	-0,66	0,67	0,85	24,54	14,03	N	0,36	N	0,73	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13658	13658	C	T	MI.22074	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1322	441	T	I	aCt/aTt	-0,98	0	0	benign	0,01	neutral	0,42	neutral	1	neutral	-2,25	neutral	1,26	neutral_impact	0,18	neutral	0,86	neutral	0,98	neutral	-0,27	0,79	0,63	0,65	neutral	0,48	neutral	0,13	neutral	0,28	neutral	0,27	5	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,13	medium_impact	1,15	medium_impact	0,16	low_impact	-1,04	0,54	0,8	24,54	14,03	N	0,42	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13658	13658	C	A	MI.22075	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1322	441	T	N	aCt/aAt	-0,98	0	0	possibly_damaging	0,73	neutral	0,34	neutral	1,04	neutral	-0,85	neutral	-2,1	neutral_impact	0,76	neutral	0,83	neutral	0,94	deleterious	2,15	17,17	0,73	0,75	disease	0,54	neutral	0,26	neutral	0,39	neutral	0,48	0	neutral	0,77	neutral	0,31	neutral	-3	deleterious	0,61	low_impact	-1,16	medium_impact	0,07	medium_impact	-0,51	0,7	0,85	24,54	14,03	N	0,37	N	0,58	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13658	13658	C	G	MI.22076	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1322	441	T	S	aCt/aGt	-0,98	0	0	benign	0,27	neutral	0,46	neutral	1,11	neutral	-0,29	neutral	-1,03	neutral_impact	-0,76	neutral	0,81	neutral	0,94	neutral	-0,81	0,04	0,68	0,7	neutral	0,38	neutral	0,03	neutral	0,15	neutral	0,2	6	neutral	0,45	deleterious	0,6	neutral	-6	neutral	0,26	medium_impact	-0,34	medium_impact	0,19	low_impact	-1,9	0,71	0,85	24,54	14,03	N	0,51	P	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13660	13660	A	G	MI.22077	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1324	442	N	D	Aac/Gac	-2,35	0	0	benign	0,18	neutral	0,22	neutral	0,92	neutral	-0,33	neutral	-1,47	low_impact	1,76	neutral	0,73	neutral	0,52	deleterious	2,42	18,92	0,85	0,9	neutral	0,46	neutral	0,24	neutral	0,49	neutral	0,45	1	neutral	0,74	deleterious	0,52	neutral	-6	deleterious	0,48	medium_impact	-0,12	medium_impact	-0,07	medium_impact	0,41	0,55	0,8	28,03	14,28	N	0,44	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13660	13660	A	T	MI.22078	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1324	442	N	Y	Aac/Tac	-2,35	0	0	benign	0,01	neutral	1	neutral	0,9	neutral	-2,61	neutral	-2,24	low_impact	1,21	neutral	0,79	neutral	0,63	deleterious	2,59	20,2	0,5	0,6	disease	0,64	neutral	0,34	neutral	0,34	disease	0,62	2	neutral	0,01	deleterious	1	neutral	-6	deleterious	0,7	medium_impact	1,15	high_impact	1,89	medium_impact	-0,1	0,48	0,8	28,03	14,28	N	0,21	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13660	13660	A	C	MI.22079	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1324	442	N	H	Aac/Cac	-2,35	0	0	benign	0,02	neutral	0,54	neutral	0,91	neutral	0,65	neutral	-1,69	low_impact	1,21	neutral	0,75	neutral	0,8	deleterious	2,03	16,41	0,71	0,75	disease	0,57	neutral	0,22	neutral	0,45	neutral	0,47	1	neutral	0,44	deleterious	0,76	neutral	-6	deleterious	0,65	medium_impact	0,86	medium_impact	0,27	medium_impact	-0,1	0,53	0,8	28,03	14,28	N	0,31	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6061	6061	T	G	MI.2208	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	158	53	I	S	aTc/aGc	4,75	1	0	possibly_damaging	0,79	deleterious	0	neutral	2,81	neutral	-1,22	deleterious	-2,99	medium_impact	3,16	neutral	0,66	neutral	0,46	deleterious	2,48	19,31	0,23	0,55	neutral	0,31	disease	0,86	neutral	0,49	disease	0,73	5	deleterious	1	neutral	0,11	deleterious	4	deleterious	0,57	low_impact	-1,3	low_impact	-1,48	medium_impact	1,82	0,63	0,9	8,97	39,65	P	0,49	N	0,62	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13661	13661	A	G	MI.22080	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1325	442	N	S	aAc/aGc	-3,27	0	0	benign	0,01	neutral	0,46	neutral	1,06	neutral	-0,31	neutral	-0,17	neutral_impact	-0,18	neutral	0,85	neutral	0,96	deleterious	-0,03	2,28	0,84	0,85	neutral	0,45	neutral	0,19	neutral	0,27	neutral	0,36	3	neutral	0,53	deleterious	0,73	neutral	-6	neutral	0,16	medium_impact	1,15	medium_impact	0,19	low_impact	-1,37	0,15	0,8	28,03	14,28	N	0,37	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13661	13661	A	C	MI.22081	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1325	442	N	T	aAc/aCc	-3,27	0	0	benign	0,01	neutral	0,45	neutral	0,95	neutral	-0,8	neutral	-0,21	neutral_impact	-0,24	neutral	0,86	neutral	0,98	deleterious	0,43	6,89	0,71	0,75	disease	0,56	neutral	0,23	neutral	0,23	disease	0,55	1	neutral	0,54	deleterious	0,72	neutral	-6	deleterious	0,43	medium_impact	1,15	medium_impact	0,18	low_impact	-1,42	0,47	0,8	28,03	14,28	N	0,37	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13661	13661	A	T	MI.22082	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1325	442	N	I	aAc/aTc	-3,27	0	0	benign	0,01	neutral	0,44	neutral	0,93	neutral	-2,73	neutral	-1,6	low_impact	1,07	neutral	0,87	neutral	0,97	deleterious	2,79	21,3	0,5	0,6	disease	0,85	neutral	0,35	neutral	0,42	disease	0,65	3	neutral	0,55	deleterious	0,72	neutral	-6	deleterious	0,7	medium_impact	1,15	medium_impact	0,18	medium_impact	-0,23	0,42	0,8	28,03	14,28	N	0,35	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13662	13662	C	A	MI.22083	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1326	442	N	K	aaC/aaA	-1,89	0	0	benign	0,18	neutral	0,31	neutral	0,96	neutral	0,1	neutral	-1,36	neutral_impact	0,48	neutral	0,74	neutral	0,67	deleterious	2,98	22,2	0,86	0,9	neutral	0,45	neutral	0,34	disease	0,52	neutral	0,49	0	neutral	0,63	deleterious	0,57	neutral	-6	deleterious	0,53	medium_impact	-0,12	medium_impact	0,04	medium_impact	-0,76	0,72	0,85	28,03	14,28	N	0,4	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13662	13662	C	G	MI.22084	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1326	442	N	K	aaC/aaG	-1,89	0	0	benign	0,18	neutral	0,31	neutral	0,96	neutral	0,1	neutral	-1,36	neutral_impact	0,48	neutral	0,74	neutral	0,67	deleterious	2,45	19,15	0,86	0,9	neutral	0,45	neutral	0,34	disease	0,52	neutral	0,49	0	neutral	0,63	deleterious	0,57	neutral	-6	deleterious	0,53	medium_impact	-0,12	medium_impact	0,04	medium_impact	-0,76	0,72	0,85	28,03	14,28	N	0,4	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13663	13663	A	C	MI.22085	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1327	443	I	L	Att/Ctt	-7,62	0	0	possibly_damaging	0,61	neutral	0,72	neutral	0,99	neutral	-0,07	neutral	-1,4	low_impact	0,94	neutral	0,79	neutral	0,79	deleterious	3,62	23,2	0,7	0,75	neutral	0,48	neutral	0,42	neutral	0,36	neutral	0,43	1	neutral	0,53	deleterious	0,56	neutral	-3	deleterious	0,65	medium_impact	-0,93	medium_impact	0,46	medium_impact	-0,34	0,53	0,8	8,96	9,53	N	0,22	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13663	13663	A	G	MI.22086	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1327	443	I	V	Att/Gtt	-7,62	0	0	benign	0,12	neutral	0,52	neutral	0,85	neutral	-0,91	neutral	-0,71	medium_impact	2,3	neutral	0,82	neutral	0,92	deleterious	3	22,2	0,63	0,65	neutral	0,37	neutral	0,22	neutral	0,41	neutral	0,37	3	neutral	0,39	deleterious	0,7	neutral	-3	deleterious	0,62	medium_impact	0,08	medium_impact	0,25	medium_impact	0,9	0,42	0,8	8,96	9,53	N	0,37	N	0,74	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13663	13663	A	T	MI.22087	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1327	443	I	F	Att/Ttt	-7,62	0	0	probably_damaging	0,97	neutral	0,79	neutral	0,75	neutral	-2,12	deleterious	-3,03	medium_impact	2,06	neutral	0,74	neutral	0,7	deleterious	3,66	23,2	0,58	0,65	disease	0,61	disease	0,63	disease	0,58	disease	0,53	1	neutral	0,97	neutral	0,41	deleterious	1	deleterious	0,74	low_impact	-2,18	medium_impact	0,55	medium_impact	0,68	0,57	0,8	8,96	9,53	N	0,22	N	0,96	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13664	13664	T	C	MI.22088	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1328	443	I	T	aTt/aCt	1,54	0,03	0	probably_damaging	0,91	neutral	0,41	neutral	0,77	neutral	-1,86	deleterious	-3,69	low_impact	1,77	neutral	0,82	neutral	0,92	deleterious	3,49	23,1	0,58	0,65	disease	0,67	disease	0,68	disease	0,57	disease	0,55	1	neutral	0,91	neutral	0,25	neutral	-2	deleterious	0,76	low_impact	-1,7	medium_impact	0,15	medium_impact	0,41	0,36	0,8	8,96	9,53	N	0,3	N	0,96	disease_causing	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13664	13664	T	A	MI.22089	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1328	443	I	N	aTt/aAt	1,54	0,03	0	probably_damaging	0,98	neutral	0,35	neutral	0,7	deleterious	-3,5	deleterious	-5,4	medium_impact	3,34	neutral	0,74	neutral	0,55	deleterious	4,56	24,4	0,53	0,6	disease	0,81	disease	0,8	disease	0,64	disease	0,73	5	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,81	low_impact	-2,35	medium_impact	0,08	medium_impact	1,85	0,6	0,8	8,96	9,53	N	0,33	N	0,99	disease_causing	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6061	6061	T	C	MI.2209	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	158	53	I	T	aTc/aCc	4,75	1	0	possibly_damaging	0,53	deleterious	0,02	neutral	2,9	neutral	-1,13	neutral	-2,31	medium_impact	2,1	neutral	0,61	neutral	0,55	deleterious	0,26	5,26	0,39	0,55	neutral	0,27	disease	0,73	neutral	0,33	disease	0,53	1	neutral	0,98	neutral	0,25	deleterious	4	neutral	0,35	medium_impact	-0,81	medium_impact	-0,75	medium_impact	0,84	0,77	0,9	8,97	39,65	P	0,49	N	0,76	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13664	13664	T	G	MI.22090	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1328	443	I	S	aTt/aGt	1,54	0,03	0	probably_damaging	0,96	neutral	0,45	neutral	0,72	neutral	-2,72	deleterious	-4,43	medium_impact	2,64	neutral	0,83	neutral	0,55	deleterious	4,39	24,1	0,52	0,6	disease	0,64	disease	0,79	disease	0,63	disease	0,64	3	neutral	0,96	neutral	0,25	deleterious	1	deleterious	0,78	low_impact	-2,06	medium_impact	0,18	medium_impact	1,21	0,37	0,8	8,96	9,53	N	0,27	N	0,96	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13665	13665	T	G	MI.22091	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1329	443	I	M	atT/atG	1,77	0,05	0	probably_damaging	0,97	neutral	0,25	neutral	0,73	neutral	-2,45	neutral	-1,85	low_impact	1,51	neutral	0,79	neutral	0,93	deleterious	2,44	19,09	0,63	0,7	disease	0,69	neutral	0,38	neutral	0,37	disease	0,63	3	neutral	0,98	neutral	0,14	neutral	-2	deleterious	0,71	low_impact	-2,18	medium_impact	-0,03	medium_impact	0,18	0,61	0,8	8,96	9,53	N	0,42	N	0,76	disease_causing	0,91	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13665	13665	T	A	MI.22092	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1329	443	I	M	atT/atA	1,77	0,05	0	probably_damaging	0,97	neutral	0,25	neutral	0,73	neutral	-2,45	neutral	-1,85	low_impact	1,51	neutral	0,79	neutral	0,93	deleterious	2,68	20,7	0,63	0,7	disease	0,69	neutral	0,38	neutral	0,37	disease	0,63	3	neutral	0,98	neutral	0,14	neutral	-2	deleterious	0,71	low_impact	-2,18	medium_impact	-0,03	medium_impact	0,18	0,61	0,8	8,96	9,53	N	0,42	N	0,76	disease_causing	0,91	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13666	13666	A	T	MI.22093	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1330	444	N	Y	Aac/Tac	-10,6	0	0	probably_damaging	1	neutral	1	neutral	0,7	neutral	-2,62	deleterious	-7,18	medium_impact	3,35	neutral	0,74	damaging	0,09	deleterious	3,83	23,4	0,48	0,55	disease	0,76	disease	0,73	disease	0,68	disease	0,69	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,79	low_impact	-3,6	high_impact	1,89	medium_impact	1,86	0,42	0,8	4,81	7,19	N	0,18	N	0,99	polymorphism	0,93	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13666	13666	A	G	MI.22094	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1330	444	N	D	Aac/Gac	-10,6	0	0	probably_damaging	1	neutral	0,22	neutral	0,73	neutral	-0,95	deleterious	-4,49	medium_impact	2,41	neutral	0,73	damaging	0,2	deleterious	3,99	23,6	0,83	0,85	disease	0,7	neutral	0,48	neutral	0,48	disease	0,56	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	-0,07	medium_impact	1	0,55	0,8	4,81	7,19	N	0,31	N	0,94	polymorphism	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13666	13666	A	C	MI.22095	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1330	444	N	H	Aac/Cac	-10,6	0	0	probably_damaging	1	neutral	0,54	neutral	0,71	neutral	1,32	deleterious	-4,49	medium_impact	2,12	neutral	0,71	damaging	0,17	deleterious	3,23	22,8	0,76	0,8	neutral	0,32	disease	0,52	disease	0,61	neutral	0,46	1	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,7	low_impact	-3,6	medium_impact	0,27	medium_impact	0,73	0,5	0,8	4,81	7,19	N	0,28	N	0,97	polymorphism	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13667	13667	A	G	MI.22096	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1331	444	N	S	aAc/aGc	2,46	0,96	0	probably_damaging	1	neutral	0,41	neutral	0,82	neutral	-0,3	deleterious	-4,48	medium_impact	2,27	neutral	0,77	damaging	0,28	deleterious	3,2	22,7	0,79	0,8	disease	0,58	disease	0,58	disease	0,55	neutral	0,48	0	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,15	medium_impact	0,87	0,19	0,8	4,81	7,19	N	0,34	N	0,82	disease_causing	0,54	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13667	13667	A	C	MI.22097	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1331	444	N	T	aAc/aCc	2,46	0,96	0	probably_damaging	1	neutral	0,4	neutral	0,74	neutral	-0,9	deleterious	-5,38	medium_impact	2,71	neutral	0,71	damaging	0,16	deleterious	3,55	23,1	0,69	0,75	disease	0,61	disease	0,73	disease	0,55	disease	0,59	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,14	medium_impact	1,27	0,49	0,8	4,81	7,19	N	0,34	N	0,94	disease_causing	0,8	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13667	13667	A	T	MI.22098	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1331	444	N	I	aAc/aTc	2,46	0,96	0	probably_damaging	1	neutral	0,4	neutral	0,68	neutral	-2,77	deleterious	-8,08	high_impact	3,69	neutral	0,71	damaging	0,09	deleterious	4,02	23,6	0,49	0,55	disease	0,74	disease	0,75	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,14	high_impact	2,17	0,39	0,8	4,81	7,19	N	0,41	N	0,99	disease_causing	0,92	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13668	13668	C	A	MI.22099	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1332	444	N	K	aaC/aaA	4,52	0,98	0	probably_damaging	1	neutral	0,31	neutral	0,78	neutral	-0,03	deleterious	-5,38	medium_impact	2,8	neutral	0,74	damaging	0,11	deleterious	4,58	24,4	0,8	0,85	neutral	0,46	disease	0,74	disease	0,67	disease	0,64	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,04	medium_impact	1,36	0,56	0,8	4,81	7,19	N	0,43	N	1	disease_causing	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8630	8630	A	T	MI.221	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	104	35	K	M	aAa/aTa	-0,1	0	0	possibly_damaging	0,9	neutral	0,21	neutral	4,35	neutral	-0,92	deleterious	-2,59	low_impact	1,04	neutral	0,89	neutral	0,59	deleterious	3,71	23,3	0,38	0,65	disease	0,81	neutral	0,25	neutral	0,37	disease	0,59	2	neutral	0,93	neutral	0,16	neutral	-3	deleterious	0,7	low_impact	-1,66	medium_impact	-0,03	medium_impact	-0,21	0,41	0,9	20,35	18,29	N	0,44	N	0,7	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6062	6062	C	G	MI.2210	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	159	53	I	M	atC/atG	7,53	1	0	possibly_damaging	0,78	deleterious	0,04	neutral	2,76	neutral	-1,12	neutral	-1,17	medium_impact	2,86	neutral	0,66	neutral	0,52	neutral	1,58	13,74	0,48	0,55	neutral	0,46	disease	0,54	neutral	0,26	neutral	0,47	1	neutral	0,97	neutral	0,13	deleterious	4	deleterious	0,46	low_impact	-1,27	medium_impact	-0,58	medium_impact	1,54	0,85	0,9	8,97	39,65	P	0,56	P	0,76	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13668	13668	C	G	MI.22100	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1332	444	N	K	aaC/aaG	4,52	0,98	0	probably_damaging	1	neutral	0,31	neutral	0,78	neutral	-0,03	deleterious	-5,38	medium_impact	2,8	neutral	0,74	damaging	0,11	deleterious	4,12	23,8	0,8	0,85	neutral	0,46	disease	0,74	disease	0,67	disease	0,64	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,04	medium_impact	1,36	0,56	0,8	4,81	7,19	N	0,42	N	1	disease_causing	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13669	13669	G	A	MI.22101	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1333	445	E	K	Gaa/Aaa	-4,87	0	0	probably_damaging	1	neutral	0,34	neutral	0,39	deleterious	-3,85	deleterious	-3,58	medium_impact	2,85	damaging	0,4	damaging	0,11	deleterious	4,67	24,5	0,68	0,7	disease	0,71	disease	0,78	disease	0,75	disease	0,65	3	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,07	medium_impact	1,4	0,77	0,85	28,69	7,14	N	0,46	N	0,99	disease_causing	0,66	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13669	13669	G	C	MI.22102	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1333	445	E	Q	Gaa/Caa	-4,87	0	0	probably_damaging	1	neutral	0,32	neutral	0,38	deleterious	-4,13	deleterious	-2,67	medium_impact	3,13	damaging	0,43	damaging	0,16	deleterious	3,51	23,1	0,69	0,75	disease	0,76	disease	0,67	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,05	medium_impact	1,66	0,72	0,85	28,69	7,14	N	0,4	N	0,89	polymorphism	0,69	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13670	13670	A	C	MI.22103	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1334	445	E	A	gAa/gCa	5,9	1	0	probably_damaging	1	neutral	0,55	neutral	0,38	deleterious	-4,14	deleterious	-5,38	high_impact	3,82	damaging	0,48	damaging	0,19	deleterious	3,86	23,5	0,54	0,6	disease	0,77	disease	0,57	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,28	high_impact	2,29	0,68	0,85	28,69	7,14	P	0,59	P	0,75	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13670	13670	A	G	MI.22104	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1334	445	E	G	gAa/gGa	5,9	1	0	probably_damaging	1	neutral	0,35	neutral	0,38	deleterious	-4,1	deleterious	-6,28	medium_impact	3,48	damaging	0,46	damaging	0,17	deleterious	4,47	24,2	0,58	0,65	disease	0,85	disease	0,58	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,08	medium_impact	1,98	0,56	0,8	28,69	7,14	P	0,63	P	0,51	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13670	13670	A	T	MI.22105	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1334	445	E	V	gAa/gTa	5,9	1	0	probably_damaging	1	neutral	0,52	neutral	0,37	deleterious	-4,42	deleterious	-6,28	high_impact	3,82	damaging	0,45	damaging	0,12	deleterious	4,4	24,1	0,39	0,5	disease	0,83	disease	0,73	disease	0,74	disease	0,77	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,25	high_impact	2,29	0,8	0,85	28,69	7,14	P	0,61	P	0,81	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13671	13671	A	C	MI.22106	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1335	445	E	D	gaA/gaC	8,42	1	0	probably_damaging	1	neutral	0,24	neutral	0,77	neutral	-0,74	deleterious	-2,69	medium_impact	2,92	damaging	0,52	damaging	0,16	deleterious	3,79	23,4	0,72	0,75	neutral	0,46	neutral	0,48	disease	0,57	neutral	0,45	1	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	-0,04	medium_impact	1,46	0,81	0,85	28,69	7,14	P	0,67	P	0,86	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13671	13671	A	T	MI.22107	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1335	445	E	D	gaA/gaT	8,42	1	0	probably_damaging	1	neutral	0,24	neutral	0,77	neutral	-0,74	deleterious	-2,69	medium_impact	2,92	damaging	0,52	damaging	0,16	deleterious	3,91	23,5	0,72	0,75	neutral	0,46	neutral	0,48	disease	0,57	neutral	0,45	1	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	-0,04	medium_impact	1,46	0,81	0,85	28,69	7,14	P	0,68	P	0,86	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13672	13672	A	C	MI.22108	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1336	446	N	H	Aat/Cat	2	1	0	probably_damaging	1	neutral	0,54	neutral	0,73	deleterious	-3,46	deleterious	-4,41	medium_impact	3,1	neutral	0,7	damaging	0,17	deleterious	3,11	22,5	0,76	0,8	disease	0,8	disease	0,69	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,27	medium_impact	1,63	0,43	0,8	2,65	7,99	N	0,32	N	0,97	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13672	13672	A	G	MI.22109	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1336	446	N	D	Aat/Gat	2	1	0	probably_damaging	1	neutral	0,22	neutral	0,78	neutral	-1,99	deleterious	-4,38	medium_impact	2,54	neutral	0,74	damaging	0,21	deleterious	3,81	23,4	0,79	0,8	disease	0,68	disease	0,51	disease	0,62	disease	0,5	0	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,07	medium_impact	1,12	0,55	0,8	2,65	7,99	N	0,46	N	0,94	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6062	6062	C	A	MI.2211	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	159	53	I	M	atC/atA	7,53	1	0	possibly_damaging	0,78	deleterious	0,04	neutral	2,76	neutral	-1,12	neutral	-1,17	medium_impact	2,86	neutral	0,66	neutral	0,52	deleterious	2,02	16,34	0,48	0,55	neutral	0,46	disease	0,54	neutral	0,26	neutral	0,47	1	neutral	0,97	neutral	0,13	deleterious	4	deleterious	0,46	low_impact	-1,27	medium_impact	-0,58	medium_impact	1,54	0,85	0,9	8,97	39,65	P	0,57	P	0,76	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13672	13672	A	T	MI.22110	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1336	446	N	Y	Aat/Tat	2	1	0	probably_damaging	1	neutral	1	neutral	0,73	deleterious	-3,68	deleterious	-7,04	medium_impact	3,29	neutral	0,74	damaging	0,11	deleterious	3,7	23,3	0,52	0,6	disease	0,86	disease	0,76	disease	0,68	disease	0,76	5	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,82	low_impact	-3,6	high_impact	1,89	medium_impact	1,8	0,44	0,8	2,65	7,99	N	0,29	N	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13673	13673	A	T	MI.22111	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1337	446	N	I	aAt/aTt	5,44	1	0	probably_damaging	1	neutral	0,42	neutral	0,72	deleterious	-4,01	deleterious	-7,9	medium_impact	2,95	neutral	0,7	damaging	0,12	deleterious	3,86	23,4	0,42	0,55	disease	0,68	disease	0,77	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,16	medium_impact	1,49	0,39	0,8	2,65	7,99	N	0,43	N	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13673	13673	A	G	MI.22112	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1337	446	N	S	aAt/aGt	5,44	1	0	probably_damaging	1	neutral	0,42	neutral	0,86	neutral	-0,95	deleterious	-4,31	medium_impact	2,75	neutral	0,77	neutral	0,68	deleterious	3,05	22,4	0,76	0,8	neutral	0,32	disease	0,51	disease	0,58	neutral	0,45	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,71	low_impact	-3,6	medium_impact	0,16	medium_impact	1,31	0,23	0,8	2,65	7,99	N	0,5	N	0,82	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13673	13673	A	C	MI.22113	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1337	446	N	T	aAt/aCt	5,44	1	0	probably_damaging	1	neutral	0,41	neutral	0,76	neutral	-2,4	deleterious	-5,18	medium_impact	2,29	neutral	0,8	neutral	0,83	deleterious	3,34	22,9	0,71	0,75	disease	0,56	disease	0,7	disease	0,56	disease	0,54	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,15	medium_impact	0,89	0,42	0,8	2,65	7,99	N	0,45	N	0,94	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13674	13674	T	G	MI.22114	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1338	446	N	K	aaT/aaG	4,29	0,98	0	probably_damaging	1	neutral	0,31	neutral	0,82	neutral	-1,48	deleterious	-5,22	medium_impact	2,95	neutral	0,71	damaging	0,12	deleterious	4,17	23,8	0,77	0,8	disease	0,5	disease	0,77	disease	0,66	disease	0,65	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,04	medium_impact	1,49	0,56	0,8	2,65	7,99	N	0,45	N	1	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13674	13674	T	A	MI.22115	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1338	446	N	K	aaT/aaA	4,29	0,98	0	probably_damaging	1	neutral	0,31	neutral	0,82	neutral	-1,48	deleterious	-5,22	medium_impact	2,95	neutral	0,71	damaging	0,12	deleterious	4,41	24,1	0,77	0,8	disease	0,5	disease	0,77	disease	0,66	disease	0,65	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,04	medium_impact	1,49	0,56	0,8	2,65	7,99	N	0,48	N	1	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13675	13675	A	T	MI.22116	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1339	447	N	Y	Aac/Tac	-4,42	0	0	benign	0,11	neutral	1	neutral	0,74	deleterious	-3,72	deleterious	-6,81	medium_impact	2,25	neutral	0,76	neutral	0,57	neutral	1,68	14,31	0,5	0,6	disease	0,88	disease	0,68	disease	0,56	disease	0,7	4	neutral	0,11	deleterious	0,95	neutral	-3	neutral	0,28	medium_impact	0,12	high_impact	1,89	medium_impact	0,85	0,29	0,8	1,99	7,82	N	0,19	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13675	13675	A	C	MI.22117	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1339	447	N	H	Aac/Cac	-4,42	0	0	possibly_damaging	0,87	neutral	0,54	neutral	0,76	neutral	-2,94	deleterious	-4,24	low_impact	1,55	neutral	0,78	neutral	0,66	deleterious	2,73	21	0,78	0,8	disease	0,76	disease	0,62	disease	0,56	disease	0,56	1	neutral	0,86	neutral	0,34	neutral	-3	deleterious	0,64	low_impact	-1,53	medium_impact	0,27	medium_impact	0,21	0,33	0,8	1,99	7,82	N	0,22	N	0,85	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13675	13675	A	G	MI.22118	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1339	447	N	D	Aac/Gac	-4,42	0	0	benign	0,08	neutral	0,21	neutral	0,85	neutral	-1,18	deleterious	-3,91	low_impact	1,8	neutral	0,82	neutral	0,83	deleterious	0,72	8,98	0,83	0,85	disease	0,52	neutral	0,38	neutral	0,37	neutral	0,37	3	neutral	0,77	deleterious	0,57	neutral	-6	neutral	0,19	medium_impact	0,26	medium_impact	-0,09	medium_impact	0,44	0,44	0,8	1,99	7,82	N	0,43	N	0,65	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13676	13676	A	C	MI.22119	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1340	447	N	T	aAc/aCc	0,4	0	0	possibly_damaging	0,64	neutral	0,4	neutral	0,8	neutral	-1,88	deleterious	-4,97	low_impact	1,8	neutral	0,78	neutral	0,66	deleterious	1,86	15,32	0,68	0,7	neutral	0,49	disease	0,61	neutral	0,35	neutral	0,48	0	neutral	0,67	neutral	0,38	neutral	-3	deleterious	0,5	medium_impact	-0,98	medium_impact	0,14	medium_impact	0,44	0,36	0,8	1,99	7,82	N	0,3	N	0,85	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6063	6063	T	C	MI.2212	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	160	54	Y	H	Tac/Cac	-4,27	0	0	probably_damaging	0,96	deleterious	0	neutral	2	deleterious	-6,36	deleterious	-3,13	high_impact	4,39	damaging	0,58	damaging	0,02	deleterious	3,44	23	0,26	0,55	disease	0,85	disease	0,87	disease	0,83	disease	0,88	8	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,88	low_impact	-2,06	low_impact	-1,48	high_impact	2,95	0,44	0,9	2,92	11,88	N	0,46	N	0,61	polymorphism	0,97	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13676	13676	A	G	MI.22120	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1340	447	N	S	aAc/aGc	0,4	0	0	benign	0,13	neutral	0,41	neutral	0,87	neutral	-0,99	deleterious	-3,99	low_impact	1,43	neutral	0,83	neutral	0,92	neutral	1,52	13,4	0,79	0,8	neutral	0,5	neutral	0,45	neutral	0,38	neutral	0,21	6	neutral	0,52	deleterious	0,64	neutral	-6	neutral	0,41	medium_impact	0,04	medium_impact	0,15	medium_impact	0,1	0,15	0,8	1,99	7,82	N	0,38	N	0,86	polymorphism	1	0,08	.	.	.	.	.	.	COSM488750	.	.	.	.	.	.	.	.
chrM	13676	13676	A	T	MI.22121	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1340	447	N	I	aAc/aTc	0,4	0	0	probably_damaging	0,91	neutral	0,4	neutral	0,75	deleterious	-3,3	deleterious	-7,63	medium_impact	2,65	neutral	0,85	neutral	0,65	deleterious	3,78	23,4	0,4	0,5	disease	0,77	disease	0,69	disease	0,6	disease	0,63	3	neutral	0,91	neutral	0,25	deleterious	1	deleterious	0,68	low_impact	-1,7	medium_impact	0,14	medium_impact	1,22	0,27	0,8	1,99	7,82	N	0,32	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13677	13677	C	A	MI.22122	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1341	447	N	K	aaC/aaA	3,15	0,1	0	possibly_damaging	0,64	neutral	0,29	neutral	0,83	neutral	-1,44	deleterious	-5,02	medium_impact	3	neutral	0,74	neutral	0,51	deleterious	3,03	22,3	0,81	0,85	disease	0,57	disease	0,72	disease	0,63	disease	0,63	3	neutral	0,75	neutral	0,33	NA	0	deleterious	0,57	medium_impact	-0,98	medium_impact	0,02	medium_impact	1,54	0,48	0,8	1,99	7,82	N	0,4	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13677	13677	C	G	MI.22123	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1341	447	N	K	aaC/aaG	3,15	0,1	0	possibly_damaging	0,64	neutral	0,29	neutral	0,83	neutral	-1,44	deleterious	-5,02	medium_impact	3	neutral	0,74	neutral	0,51	deleterious	2,59	20,1	0,81	0,85	disease	0,57	disease	0,72	disease	0,63	disease	0,63	3	neutral	0,75	neutral	0,33	NA	0	deleterious	0,57	medium_impact	-0,98	medium_impact	0,02	medium_impact	1,54	0,48	0,8	1,99	7,82	N	0,39	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13678	13678	C	A	MI.22124	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1342	448	P	T	Ccc/Acc	-0,52	0	0	possibly_damaging	0,64	neutral	0,41	neutral	0,89	neutral	-1,97	deleterious	-5,61	medium_impact	2,08	neutral	0,86	neutral	0,94	deleterious	3,62	23,2	0,48	0,55	disease	0,62	disease	0,51	neutral	0,3	neutral	0,49	0	neutral	0,67	neutral	0,39	NA	0	deleterious	0,56	medium_impact	-0,98	medium_impact	0,15	medium_impact	0,7	0,49	0,8	2,65	8,71	N	0,35	N	0,91	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13678	13678	C	T	MI.22125	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1342	448	P	S	Ccc/Tcc	-0,52	0	0	benign	0,09	neutral	0,43	neutral	0,92	neutral	-1,86	deleterious	-5,91	medium_impact	2,31	neutral	0,87	neutral	0,76	deleterious	2,05	16,52	0,54	0,6	disease	0,64	disease	0,53	neutral	0,32	neutral	0,49	0	neutral	0,51	deleterious	0,67	neutral	-3	neutral	0,26	medium_impact	0,21	medium_impact	0,17	medium_impact	0,91	0,21	0,8	2,65	8,71	N	0,37	N	0,78	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13678	13678	C	G	MI.22126	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1342	448	P	A	Ccc/Gcc	-0,52	0	0	benign	0,4	neutral	0,53	neutral	0,9	neutral	-1,06	deleterious	-6,03	medium_impact	3,06	neutral	0,8	neutral	0,72	neutral	1,61	13,89	0,48	0,55	disease	0,51	neutral	0,35	disease	0,57	neutral	0,46	1	neutral	0,41	deleterious	0,57	neutral	-3	deleterious	0,44	medium_impact	-0,58	medium_impact	0,26	medium_impact	1,59	0,62	0,8	2,65	8,71	N	0,32	N	0,73	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13679	13679	C	A	MI.22127	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1343	448	P	H	cCc/cAc	-0,06	0	0	probably_damaging	0,96	neutral	0,54	neutral	0,84	deleterious	-3,59	deleterious	-6,98	medium_impact	3,06	neutral	0,77	neutral	0,59	deleterious	4,13	23,8	0,42	0,55	disease	0,79	disease	0,64	disease	0,55	disease	0,6	2	neutral	0,96	neutral	0,29	deleterious	1	deleterious	0,77	low_impact	-2,06	medium_impact	0,27	medium_impact	1,59	0,4	0,8	2,65	8,71	N	0,25	N	0,72	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13679	13679	C	G	MI.22128	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1343	448	P	R	cCc/cGc	-0,06	0	0	probably_damaging	0,91	neutral	0,36	neutral	0,87	neutral	-1,92	deleterious	-6,87	medium_impact	2,86	neutral	0,74	neutral	0,55	deleterious	3,63	23,2	0,36	0,5	disease	0,66	disease	0,68	disease	0,67	disease	0,68	4	neutral	0,91	neutral	0,23	deleterious	1	deleterious	0,72	low_impact	-1,7	medium_impact	0,1	medium_impact	1,41	0,47	0,8	2,65	8,71	N	0,29	N	0,64	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13679	13679	C	T	MI.22129	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1343	448	P	L	cCc/cTc	-0,06	0	0	benign	0,08	neutral	0,67	neutral	0,92	neutral	-1,07	deleterious	-7,62	medium_impact	2,37	neutral	0,82	neutral	0,65	deleterious	4,36	24,1	0,47	0,55	neutral	0,37	disease	0,6	disease	0,55	neutral	0,47	1	neutral	0,24	deleterious	0,8	neutral	-3	deleterious	0,61	medium_impact	0,26	medium_impact	0,4	medium_impact	0,96	0,66	0,8	2,65	8,71	N	0,28	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6063	6063	T	A	MI.2213	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	160	54	Y	N	Tac/Aac	-4,27	0	0	probably_damaging	1	deleterious	0	neutral	1,99	deleterious	-8,03	deleterious	-5,61	high_impact	5,08	damaging	0,58	damaging	0,04	deleterious	3,87	23,5	0,22	0,55	disease	0,91	disease	0,9	disease	0,77	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,59	0,24	0,9	2,92	11,88	P	0,58	P	0,94	polymorphism	0,75	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13681	13681	A	G	MI.22130	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1345	449	T	A	Acc/Gcc	-9,46	0	0,02	benign	0,01	neutral	0,51	neutral	0,95	neutral	-0,44	neutral	-0,25	neutral_impact	0,21	neutral	0,78	neutral	0,88	neutral	-0,07	1,98	0,68	0,7	neutral	0,5	neutral	0,05	neutral	0,18	neutral	0,18	6	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,13	medium_impact	1,15	medium_impact	0,24	low_impact	-1,01	0,35	0,8	33,67	22,11	N	0,46	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13681	13681	A	C	MI.22131	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1345	449	T	P	Acc/Ccc	-9,46	0	0,02	possibly_damaging	0,66	neutral	0,29	neutral	0,87	neutral	-2,59	neutral	-0,86	neutral_impact	0,77	neutral	0,82	neutral	0,9	deleterious	2,5	19,48	0,25	0,45	neutral	0,44	neutral	0,46	neutral	0,49	neutral	0,47	1	neutral	0,76	neutral	0,32	neutral	-3	deleterious	0,63	low_impact	-1,02	medium_impact	0,02	medium_impact	-0,5	0,51	0,8	33,67	22,11	N	0,38	N	0,7	polymorphism	1	0,01	rs386829187	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13681	13681	A	T	MI.22132	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1345	449	T	S	Acc/Tcc	-9,46	0	0,02	benign	0,03	neutral	0,42	neutral	0,98	neutral	-0,99	neutral	0,1	neutral_impact	0,77	neutral	0,86	neutral	0,97	deleterious	0,09	3,46	0,58	0,65	disease	0,51	neutral	0,09	neutral	0,17	neutral	0,29	4	neutral	0,55	deleterious	0,7	neutral	-6	neutral	0,15	medium_impact	0,69	medium_impact	0,16	medium_impact	-0,5	0,6	0,8	33,67	22,11	N	0,55	P	0,21	polymorphism	1	0	rs386829187	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13682	13682	C	T	MI.22133	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1346	449	T	I	aCc/aTc	-8,31	0	0	benign	0,37	neutral	0,48	neutral	1	neutral	-0,46	neutral	-0,28	low_impact	0,97	neutral	0,78	neutral	0,71	deleterious	2,16	17,28	0,45	0,55	neutral	0,42	neutral	0,2	neutral	0,35	neutral	0,37	3	neutral	0,45	deleterious	0,56	neutral	-6	deleterious	0,53	medium_impact	-0,53	medium_impact	0,21	medium_impact	-0,32	0,55	0,8	33,67	22,11	N	0,34	N	0,22	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13682	13682	C	A	MI.22134	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1346	449	T	N	aCc/aAc	-8,31	0	0	benign	0,37	neutral	0,37	neutral	0,98	neutral	-2,2	neutral	-0,47	neutral_impact	-0,48	neutral	0,81	neutral	0,93	neutral	1,59	13,79	0,58	0,65	disease	0,59	neutral	0,16	neutral	0,19	neutral	0,32	4	neutral	0,56	deleterious	0,5	neutral	-6	deleterious	0,51	medium_impact	-0,53	medium_impact	0,11	low_impact	-1,64	0,67	0,85	33,67	22,11	N	0,43	N	0,14	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13682	13682	C	G	MI.22135	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1346	449	T	S	aCc/aGc	-8,31	0	0	benign	0,03	neutral	0,42	neutral	0,98	neutral	-0,99	neutral	0,1	neutral_impact	0,77	neutral	0,86	neutral	0,97	neutral	-0,25	0,88	0,58	0,65	disease	0,51	neutral	0,09	neutral	0,17	neutral	0,29	4	neutral	0,55	deleterious	0,7	neutral	-6	neutral	0,15	medium_impact	0,69	medium_impact	0,16	medium_impact	-0,5	0,6	0,8	33,67	22,11	N	0,49	N	0,21	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13684	13684	C	G	MI.22136	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1348	450	L	V	Cta/Gta	-6,25	0	0	possibly_damaging	0,9	neutral	0,55	neutral	0,92	neutral	-0,6	deleterious	-2,5	low_impact	1,4	neutral	0,68	neutral	0,42	neutral	1,61	13,91	0,42	0,55	disease	0,6	neutral	0,06	neutral	0,18	neutral	0,36	3	neutral	0,88	neutral	0,33	neutral	-3	deleterious	0,69	low_impact	-1,65	medium_impact	0,28	medium_impact	0,08	0,65	0,8	2,99	8,09	N	0,34	N	0,81	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13684	13684	C	A	MI.22137	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1348	450	L	M	Cta/Ata	-6,25	0	0	possibly_damaging	0,76	neutral	0,25	neutral	0,97	neutral	1,12	neutral	-1,51	low_impact	1,49	neutral	0,73	neutral	0,65	deleterious	2,64	20,4	0,35	0,5	neutral	0,3	neutral	0,18	neutral	0,25	neutral	0,34	3	neutral	0,84	neutral	0,25	neutral	-3	deleterious	0,67	low_impact	-1,22	medium_impact	-0,03	medium_impact	0,16	0,6	0,8	2,99	8,09	N	0,44	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13685	13685	T	C	MI.22138	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1349	450	L	P	cTa/cCa	-0,75	0	0	probably_damaging	1	neutral	0,28	neutral	0,73	deleterious	-3,64	deleterious	-6,07	low_impact	1,9	damaging	0,58	damaging	0,13	deleterious	4,01	23,6	0,18	0,45	disease	0,81	disease	0,8	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,89	low_impact	-3,6	medium_impact	0,01	medium_impact	0,53	0,61	0,8	2,99	8,09	N	0,21	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13685	13685	T	A	MI.22139	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1349	450	L	Q	cTa/cAa	-0,75	0	0	probably_damaging	0,99	neutral	0,38	neutral	0,74	deleterious	-3,28	deleterious	-5,14	medium_impact	2,1	neutral	0,71	damaging	0,18	deleterious	4,17	23,8	0,22	0,45	disease	0,84	disease	0,65	neutral	0,5	disease	0,62	2	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,84	low_impact	-2,64	medium_impact	0,12	medium_impact	0,72	0,68	0,85	2,99	8,09	N	0,26	N	0,98	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6063	6063	T	G	MI.2214	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	160	54	Y	D	Tac/Gac	-4,27	0	0	probably_damaging	1	deleterious	0	neutral	1,99	deleterious	-8,98	deleterious	-6,22	high_impact	5,08	damaging	0,5	damaging	0,03	deleterious	3,8	23,4	0,14	0,55	disease	0,94	disease	0,91	disease	0,84	disease	0,89	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,59	0,24	0,9	2,92	11,88	P	0,5	N	0,98	polymorphism	0,8	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13685	13685	T	G	MI.22140	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1349	450	L	R	cTa/cGa	-0,75	0	0	probably_damaging	0,99	neutral	0,43	neutral	0,73	deleterious	-3,03	deleterious	-5,18	medium_impact	3,25	neutral	0,64	damaging	0,07	deleterious	4,31	24	0,21	0,45	disease	0,86	disease	0,75	disease	0,73	disease	0,8	6	deleterious	0,99	neutral	0,22	deleterious	1	deleterious	0,88	low_impact	-2,64	medium_impact	0,17	medium_impact	1,77	0,57	0,8	2,99	8,09	N	0,24	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13687	13687	C	A	MI.22141	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1351	451	L	M	Cta/Ata	-6,94	0	0	benign	0,29	neutral	0,23	neutral	0,77	neutral	-1,96	neutral	-0,42	neutral_impact	-0,05	neutral	0,79	neutral	0,92	deleterious	2,51	19,53	0,36	0,5	disease	0,69	neutral	0,21	neutral	0,19	disease	0,52	0	neutral	0,72	deleterious	0,47	neutral	-6	deleterious	0,7	medium_impact	-0,38	medium_impact	-0,06	low_impact	-1,25	0,83	0,85	20,73	16,89	N	0,43	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13687	13687	C	G	MI.22142	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1351	451	L	V	Cta/Gta	-6,94	0	0	possibly_damaging	0,62	neutral	0,5	neutral	0,89	neutral	-1,28	neutral	0,4	low_impact	0,98	neutral	0,8	neutral	0,93	deleterious	2,46	19,21	0,42	0,55	disease	0,51	neutral	0,3	neutral	0,24	neutral	0,36	3	neutral	0,6	neutral	0,44	neutral	-3	deleterious	0,68	medium_impact	-0,95	medium_impact	0,23	medium_impact	-0,31	0,56	0,8	20,73	16,89	N	0,35	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13688	13688	T	A	MI.22143	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1352	451	L	Q	cTa/cAa	0,4	0	0	probably_damaging	0,94	neutral	0,28	neutral	0,75	deleterious	-3,68	deleterious	-2,96	medium_impact	2,13	neutral	0,75	damaging	0,27	deleterious	4,28	24	0,27	0,45	disease	0,75	disease	0,66	disease	0,56	disease	0,72	4	neutral	0,95	neutral	0,17	deleterious	1	deleterious	0,8	low_impact	-1,88	medium_impact	0,01	medium_impact	0,74	0,51	0,8	20,73	16,89	N	0,28	N	0,87	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13688	13688	T	C	MI.22144	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1352	451	L	P	cTa/cCa	0,4	0	0	probably_damaging	0,96	neutral	0,26	neutral	0,74	deleterious	-4,46	deleterious	-3,29	medium_impact	2,13	damaging	0,57	damaging	0,19	deleterious	4,05	23,7	0,18	0,45	disease	0,9	disease	0,83	disease	0,7	disease	0,83	7	neutral	0,97	neutral	0,15	deleterious	1	deleterious	0,88	low_impact	-2,06	medium_impact	-0,02	medium_impact	0,74	0,45	0,8	20,73	16,89	N	0,23	N	0,91	polymorphism	1	0,2	.	.	.	.	.	.	COSM488751	.	.	.	.	.	.	.	.
chrM	13688	13688	T	G	MI.22145	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1352	451	L	R	cTa/cGa	0,4	0	0	possibly_damaging	0,82	neutral	0,34	neutral	0,75	neutral	-2,95	deleterious	-3,04	low_impact	1,79	neutral	0,66	damaging	0,24	deleterious	4,27	23,9	0,25	0,45	disease	0,62	disease	0,78	disease	0,7	disease	0,78	6	neutral	0,84	neutral	0,26	neutral	-3	deleterious	0,83	low_impact	-1,37	medium_impact	0,07	medium_impact	0,43	0,52	0,8	20,73	16,89	N	0,24	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13690	13690	A	T	MI.22146	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1354	452	N	Y	Aac/Tac	-12,67	0	0	probably_damaging	0,98	neutral	1	neutral	0,72	deleterious	-3,62	deleterious	-6,7	medium_impact	3,19	neutral	0,74	neutral	0,41	deleterious	3,78	23,4	0,48	0,55	disease	0,67	disease	0,85	disease	0,68	disease	0,68	4	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,81	low_impact	-2,35	high_impact	1,89	medium_impact	1,71	0,46	0,8	4,48	7,21	N	0,21	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13690	13690	A	C	MI.22147	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1354	452	N	H	Aac/Cac	-12,67	0	0	probably_damaging	0,98	neutral	0,54	neutral	0,72	deleterious	-3,54	deleterious	-4,08	medium_impact	3,19	neutral	0,79	neutral	0,47	deleterious	3,13	22,6	0,52	0,6	disease	0,82	disease	0,78	disease	0,65	disease	0,7	4	neutral	0,97	neutral	0,28	deleterious	1	deleterious	0,8	low_impact	-2,35	medium_impact	0,27	medium_impact	1,71	0,53	0,8	4,48	7,21	N	0,22	N	0,78	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13690	13690	A	G	MI.22148	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1354	452	N	D	Aac/Gac	-12,67	0	0	possibly_damaging	0,8	neutral	0,21	neutral	0,75	neutral	-2,54	deleterious	-4,2	high_impact	3,75	neutral	0,7	neutral	0,43	deleterious	3,58	23,2	0,65	0,7	disease	0,91	disease	0,75	disease	0,7	disease	0,79	6	neutral	0,88	neutral	0,21	deleterious	1	deleterious	0,68	low_impact	-1,32	medium_impact	-0,09	high_impact	2,22	0,59	0,8	4,48	7,21	N	0,38	N	0,89	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13691	13691	A	T	MI.22149	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1355	452	N	I	aAc/aTc	3,83	0,78	0	probably_damaging	0,97	neutral	0,4	neutral	0,73	deleterious	-3,02	deleterious	-7,64	medium_impact	3,4	neutral	0,73	neutral	0,52	deleterious	3,87	23,5	0,43	0,55	neutral	0,41	disease	0,83	disease	0,63	disease	0,55	1	neutral	0,97	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-2,18	medium_impact	0,14	medium_impact	1,9	0,38	0,8	4,48	7,21	N	0,37	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6064	6064	A	T	MI.2215	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	161	54	Y	F	tAc/tTc	7,53	1	0	benign	0,03	deleterious	0,03	neutral	2,66	neutral	-0,77	neutral	-2,39	medium_impact	2,26	damaging	0,48	damaging	0,12	deleterious	3,33	22,9	0,27	0,55	neutral	0,47	disease	0,8	disease	0,53	disease	0,51	0	neutral	0,97	deleterious	0,5	deleterious	1	neutral	0,32	medium_impact	0,66	medium_impact	-0,65	medium_impact	0,99	0,63	0,9	2,92	11,88	P	0,52	P	0,5	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13691	13691	A	C	MI.22150	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1355	452	N	T	aAc/aCc	3,83	0,78	0	possibly_damaging	0,88	neutral	0,4	neutral	0,76	neutral	-2,21	deleterious	-5,01	medium_impact	3,4	neutral	0,75	neutral	0,6	deleterious	3,17	22,7	0,5	0,6	disease	0,54	disease	0,81	disease	0,62	disease	0,65	3	neutral	0,88	neutral	0,26	NA	0	deleterious	0,68	low_impact	-1,57	medium_impact	0,14	medium_impact	1,9	0,58	0,8	4,48	7,21	N	0,38	N	0,78	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13691	13691	A	G	MI.22151	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1355	452	N	S	aAc/aGc	3,83	0,78	0	possibly_damaging	0,74	neutral	0,41	neutral	0,83	neutral	-1,21	deleterious	-4,06	medium_impact	2,5	neutral	0,78	neutral	0,69	neutral	1,48	13,2	0,65	0,7	disease	0,66	disease	0,73	disease	0,53	disease	0,55	1	neutral	0,75	neutral	0,34	NA	0	deleterious	0,64	low_impact	-1,18	medium_impact	0,15	medium_impact	1,08	0,4	0,8	4,48	7,21	N	0,32	N	0,81	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13692	13692	C	A	MI.22152	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1356	452	N	K	aaC/aaA	2,46	0,76	0	benign	0,12	neutral	0,3	neutral	0,86	neutral	-0,9	deleterious	-4,83	medium_impact	2,2	neutral	0,8	neutral	0,6	neutral	1,59	13,79	0,73	0,75	disease	0,76	disease	0,81	disease	0,53	disease	0,58	2	neutral	0,65	deleterious	0,59	neutral	-3	neutral	0,31	medium_impact	0,08	medium_impact	0,03	medium_impact	0,81	0,55	0,8	4,48	7,21	N	0,3	N	0,51	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13692	13692	C	G	MI.22153	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1356	452	N	K	aaC/aaG	2,46	0,76	0	benign	0,12	neutral	0,3	neutral	0,86	neutral	-0,9	deleterious	-4,83	medium_impact	2,2	neutral	0,8	neutral	0,6	neutral	1,16	11,51	0,73	0,75	disease	0,76	disease	0,81	disease	0,53	disease	0,58	2	neutral	0,65	deleterious	0,59	neutral	-3	neutral	0,31	medium_impact	0,08	medium_impact	0,03	medium_impact	0,81	0,55	0,8	4,48	7,21	N	0,3	N	0,51	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13693	13693	C	T	MI.22154	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1357	453	P	S	Ccc/Tcc	-2,35	0	0	possibly_damaging	0,66	neutral	0,42	neutral	0,64	neutral	-1,2	neutral	-2,44	low_impact	1,75	neutral	0,8	neutral	0,95	deleterious	2,59	20,1	0,44	0,55	disease	0,53	disease	0,64	neutral	0,43	neutral	0,48	0	neutral	0,68	neutral	0,38	neutral	-3	deleterious	0,78	low_impact	-1,02	medium_impact	0,16	medium_impact	0,4	0,43	0,8	11,28	14,66	N	0,28	N	0,07	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13693	13693	C	A	MI.22155	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1357	453	P	T	Ccc/Acc	-2,35	0	0	probably_damaging	0,94	neutral	0,4	neutral	0,35	deleterious	-3,73	deleterious	-3,41	medium_impact	2,88	neutral	0,63	damaging	0,23	deleterious	3,97	23,6	0,29	0,45	disease	0,71	disease	0,8	disease	0,61	disease	0,68	4	neutral	0,94	neutral	0,23	deleterious	1	deleterious	0,81	low_impact	-1,88	medium_impact	0,14	medium_impact	1,43	0,8	0,85	11,28	14,66	N	0,23	N	0,67	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13693	13693	C	G	MI.22156	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1357	453	P	A	Ccc/Gcc	-2,35	0	0	possibly_damaging	0,9	neutral	0,52	neutral	0,42	neutral	-2,72	deleterious	-3,01	medium_impact	2,58	neutral	0,7	neutral	0,64	deleterious	3,17	22,7	0,24	0,45	disease	0,53	disease	0,57	disease	0,62	neutral	0,49	0	neutral	0,89	neutral	0,31	NA	0	deleterious	0,76	low_impact	-1,65	medium_impact	0,25	medium_impact	1,15	0,77	0,85	11,28	14,66	N	0,28	N	0,75	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13694	13694	C	G	MI.22157	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1358	453	P	R	cCc/cGc	-0,06	0	0	probably_damaging	0,98	neutral	0,36	neutral	0,3	deleterious	-5,76	deleterious	-4,6	high_impact	3,78	neutral	0,61	damaging	0,14	deleterious	3,73	23,3	0,19	0,45	disease	0,82	disease	0,85	disease	0,8	disease	0,83	7	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,86	low_impact	-2,35	medium_impact	0,1	high_impact	2,25	0,66	0,8	11,28	14,66	N	0,39	N	0,93	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13694	13694	C	T	MI.22158	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1358	453	P	L	cCc/cTc	-0,06	0	0	probably_damaging	0,98	neutral	0,69	neutral	0,3	deleterious	-5,75	deleterious	-5,4	high_impact	3,78	neutral	0,61	damaging	0,17	deleterious	4,54	24,3	0,34	0,5	disease	0,68	disease	0,84	disease	0,67	disease	0,73	5	deleterious	0,98	neutral	0,36	deleterious	2	deleterious	0,81	low_impact	-2,35	medium_impact	0,42	high_impact	2,25	0,78	0,85	11,28	14,66	N	0,25	N	0,97	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13694	13694	C	A	MI.22159	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1358	453	P	H	cCc/cAc	-0,06	0	0	probably_damaging	1	neutral	0,54	neutral	0,29	deleterious	-6,75	deleterious	-4,69	high_impact	3,78	neutral	0,62	damaging	0,16	deleterious	4,16	23,8	0,23	0,45	disease	0,89	disease	0,83	disease	0,79	disease	0,86	7	deleterious	0,99	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,27	high_impact	2,25	0,72	0,85	11,28	14,66	N	0,38	N	0,86	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6064	6064	A	G	MI.2216	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	161	54	Y	C	tAc/tGc	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	1,99	deleterious	-8,2	deleterious	-5,59	high_impact	5,08	damaging	0,5	damaging	0,03	deleterious	3,42	23	0,24	0,55	disease	0,95	disease	0,91	disease	0,78	disease	0,88	8	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-2,35	low_impact	-1,48	high_impact	3,59	0,21	0,9	2,92	11,88	P	0,6	P	0,89	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13696	13696	A	T	MI.22160	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1360	454	I	F	Att/Ttt	-20	0	0	possibly_damaging	0,77	neutral	0,72	neutral	0,6	deleterious	-3,73	deleterious	-3,46	medium_impact	3,08	neutral	0,66	neutral	0,36	deleterious	4,14	23,8	0,34	0,5	disease	0,7	disease	0,83	disease	0,64	disease	0,71	4	neutral	0,72	deleterious	0,48	NA	0	deleterious	0,8	low_impact	-1,24	medium_impact	0,46	medium_impact	1,61	0,79	0,85	7,46	13,31	N	0,22	N	0,96	polymorphism	0,71	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13696	13696	A	G	MI.22161	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1360	454	I	V	Att/Gtt	-20	0	0	benign	0,42	neutral	0,54	neutral	0,73	neutral	-1,5	neutral	-0,81	medium_impact	3,28	neutral	0,82	neutral	0,66	deleterious	3,14	22,6	0,57	0,65	disease	0,52	neutral	0,49	neutral	0,5	neutral	0,45	1	neutral	0,42	deleterious	0,56	neutral	-3	deleterious	0,66	medium_impact	-0,61	medium_impact	0,27	medium_impact	1,79	0,63	0,8	7,46	13,31	N	0,29	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13696	13696	A	C	MI.22162	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1360	454	I	L	Att/Ctt	-20	0	0	benign	0,03	neutral	0,82	neutral	0,86	neutral	-0,64	neutral	-1,66	low_impact	0,97	neutral	0,81	neutral	0,74	deleterious	2,8	21,4	0,36	0,5	neutral	0,35	neutral	0,34	neutral	0,26	neutral	0,44	1	neutral	0,12	deleterious	0,9	neutral	-6	deleterious	0,65	medium_impact	0,69	medium_impact	0,6	medium_impact	-0,32	0,8	0,85	7,46	13,31	N	0,32	N	0,86	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13697	13697	T	A	MI.22163	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1361	454	I	N	aTt/aAt	2,23	0,96	0	probably_damaging	0,95	neutral	0,34	neutral	0,58	deleterious	-5,33	deleterious	-5,97	high_impact	3,62	neutral	0,66	neutral	0,43	deleterious	4,51	24,3	0,22	0,45	disease	0,89	disease	0,9	disease	0,62	disease	0,8	6	neutral	0,96	neutral	0,2	deleterious	2	deleterious	0,86	low_impact	-1,96	medium_impact	0,07	high_impact	2,1	0,7	0,85	7,46	13,31	N	0,45	N	0,99	disease_causing	0,99	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13697	13697	T	G	MI.22164	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1361	454	I	S	aTt/aGt	2,23	0,96	0	possibly_damaging	0,86	neutral	0,47	neutral	0,6	deleterious	-3,62	deleterious	-5,07	high_impact	3,62	neutral	0,7	neutral	0,49	deleterious	4,41	24,1	0,21	0,45	disease	0,67	disease	0,9	disease	0,62	disease	0,74	5	neutral	0,85	neutral	0,31	deleterious	1	deleterious	0,83	low_impact	-1,5	medium_impact	0,2	high_impact	2,1	0,59	0,8	7,46	13,31	N	0,46	N	0,96	disease_causing	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13697	13697	T	C	MI.22165	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1361	454	I	T	aTt/aCt	2,23	0,96	0	possibly_damaging	0,79	neutral	0,45	neutral	0,61	deleterious	-3,37	deleterious	-4,06	high_impact	3,62	neutral	0,69	neutral	0,47	deleterious	3,46	23	0,27	0,45	disease	0,68	disease	0,8	disease	0,52	disease	0,63	3	neutral	0,78	neutral	0,33	deleterious	1	deleterious	0,8	low_impact	-1,29	medium_impact	0,18	high_impact	2,1	0,64	0,8	7,46	13,31	N	0,44	N	0,96	disease_causing	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13698	13698	T	G	MI.22166	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1362	454	I	M	atT/atG	5,67	0,99	0	benign	0,15	neutral	0,28	neutral	0,91	neutral	-0,38	deleterious	-2,52	medium_impact	2,42	neutral	0,75	neutral	0,5	deleterious	3,48	23,1	0,57	0,65	neutral	0,36	disease	0,68	neutral	0,44	disease	0,51	0	neutral	0,67	deleterious	0,57	neutral	-3	deleterious	0,69	medium_impact	-0,03	medium_impact	0,01	medium_impact	1,01	0,84	0,9	7,46	13,31	P	0,59	P	0,76	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13698	13698	T	A	MI.22167	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1362	454	I	M	atT/atA	5,67	0,99	0	benign	0,15	neutral	0,28	neutral	0,91	neutral	-0,38	deleterious	-2,52	medium_impact	2,42	neutral	0,75	neutral	0,5	deleterious	3,72	23,3	0,57	0,65	neutral	0,36	disease	0,68	neutral	0,44	disease	0,51	0	neutral	0,67	deleterious	0,57	neutral	-3	deleterious	0,69	medium_impact	-0,03	medium_impact	0,01	medium_impact	1,01	0,84	0,9	7,46	13,31	P	0,59	P	0,76	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13699	13699	A	G	MI.22168	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1363	455	K	E	Aaa/Gaa	-4,64	0	0	possibly_damaging	0,62	neutral	0,27	neutral	0,84	neutral	-0,31	deleterious	-3,15	medium_impact	2,8	neutral	0,74	neutral	0,53	deleterious	4,15	23,8	0,44	0,55	disease	0,61	disease	0,8	disease	0,64	disease	0,7	4	neutral	0,75	neutral	0,33	NA	0	deleterious	0,81	medium_impact	-0,95	medium_impact	-0,01	medium_impact	1,36	0,75	0,85	23,55	18,35	N	0,31	N	0,79	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13699	13699	A	C	MI.22169	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1363	455	K	Q	Aaa/Caa	-4,64	0	0	possibly_damaging	0,86	neutral	0,29	neutral	0,84	neutral	-0,96	deleterious	-3,13	medium_impact	2,6	neutral	0,78	neutral	0,51	deleterious	3,57	23,1	0,51	0,6	disease	0,72	disease	0,71	disease	0,56	disease	0,62	2	neutral	0,89	neutral	0,22	NA	0	deleterious	0,79	low_impact	-1,5	medium_impact	0,02	medium_impact	1,17	0,78	0,85	23,55	18,35	N	0,27	N	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6064	6064	A	C	MI.2217	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	161	54	Y	S	tAc/tCc	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	1,99	deleterious	-7,81	deleterious	-5,59	high_impact	5,08	damaging	0,58	damaging	0,04	deleterious	3,59	23,2	0,2	0,55	disease	0,87	disease	0,9	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,35	low_impact	-1,48	high_impact	3,59	0,33	0,9	2,92	11,88	P	0,64	P	0,9	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13700	13700	A	C	MI.22170	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1364	455	K	T	aAa/aCa	3,61	0,79	0	possibly_damaging	0,66	neutral	0,44	neutral	0,94	neutral	0,71	deleterious	-4,61	low_impact	1,37	neutral	0,83	neutral	0,7	deleterious	3,69	23,3	0,23	0,45	disease	0,51	neutral	0,5	neutral	0,3	neutral	0,46	1	neutral	0,66	neutral	0,39	neutral	-3	deleterious	0,73	low_impact	-1,02	medium_impact	0,18	medium_impact	0,05	0,56	0,8	23,55	18,35	N	0,31	N	0,78	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13700	13700	A	T	MI.22171	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1364	455	K	M	aAa/aTa	3,61	0,79	0	probably_damaging	0,98	neutral	0,31	neutral	0,89	neutral	0,9	deleterious	-4,82	low_impact	1,45	neutral	0,85	neutral	0,74	deleterious	2,99	22,2	0,26	0,45	disease	0,56	disease	0,6	neutral	0,29	neutral	0,49	0	neutral	0,98	neutral	0,17	neutral	-2	deleterious	0,73	low_impact	-2,35	medium_impact	0,04	medium_impact	0,12	0,59	0,8	23,55	18,35	N	0,32	N	0,52	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13701	13701	A	T	MI.22172	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1365	455	K	N	aaA/aaT	1,31	0,77	0	benign	0,05	neutral	0,35	neutral	0,84	neutral	-1,22	deleterious	-3,62	medium_impact	2,8	neutral	0,84	neutral	0,64	deleterious	4,01	23,6	0,52	0,6	disease	0,67	disease	0,71	disease	0,56	disease	0,62	2	neutral	0,62	deleterious	0,65	neutral	-3	deleterious	0,8	medium_impact	0,47	medium_impact	0,08	medium_impact	1,36	0,78	0,85	23,55	18,35	N	0,28	N	0,66	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13701	13701	A	C	MI.22173	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1365	455	K	N	aaA/aaC	1,31	0,77	0	benign	0,05	neutral	0,35	neutral	0,84	neutral	-1,22	deleterious	-3,62	medium_impact	2,8	neutral	0,84	neutral	0,64	deleterious	3,95	23,6	0,52	0,6	disease	0,67	disease	0,71	disease	0,56	disease	0,62	2	neutral	0,62	deleterious	0,65	neutral	-3	deleterious	0,8	medium_impact	0,47	medium_impact	0,08	medium_impact	1,36	0,78	0,85	23,55	18,35	N	0,28	N	0,66	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13702	13702	C	A	MI.22174	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1366	456	R	S	Cgc/Agc	0,17	0,74	0	probably_damaging	1	neutral	0,47	neutral	0,72	neutral	0,01	deleterious	-5,38	high_impact	3,56	damaging	0,59	neutral	0,33	deleterious	4,8	24,8	0,32	0,5	disease	0,57	disease	0,88	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,2	high_impact	2,05	0,6	0,8	26,2	7,33	N	0,29	N	0,82	disease_causing	0,73	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13702	13702	C	T	MI.22175	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1366	456	R	C	Cgc/Tgc	0,17	0,74	0	probably_damaging	1	neutral	0,18	neutral	0,68	neutral	-1,28	deleterious	-7,18	high_impact	3,92	neutral	0,61	damaging	0,18	deleterious	5,1	25,3	0,37	0,5	disease	0,73	disease	0,9	disease	0,77	disease	0,81	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,13	high_impact	2,38	0,76	0,85	26,2	7,33	N	0,4	N	1	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13702	13702	C	G	MI.22176	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1366	456	R	G	Cgc/Ggc	0,17	0,74	0	probably_damaging	1	neutral	0,4	neutral	0,77	neutral	-0,31	deleterious	-6,28	medium_impact	3,37	damaging	0,54	neutral	0,34	deleterious	4,32	24	0,33	0,5	disease	0,64	disease	0,8	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,14	medium_impact	1,88	0,55	0,8	26,2	7,33	N	0,32	N	0,97	disease_causing	0,72	0,1	rs2853813	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13703	13703	G	C	MI.22177	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1367	456	R	P	cGc/cCc	3,38	1	0	probably_damaging	1	neutral	0,26	neutral	0,68	neutral	-1,16	deleterious	-6,28	high_impact	3,92	damaging	0,55	damaging	0,25	deleterious	4,34	24	0,23	0,45	disease	0,63	disease	0,92	disease	0,81	disease	0,84	7	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,02	high_impact	2,38	0,48	0,8	26,2	7,33	P	0,53	P	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13703	13703	G	T	MI.22178	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1367	456	R	L	cGc/cTc	3,38	1	0	probably_damaging	1	neutral	0,9	neutral	0,82	neutral	1,86	deleterious	-6,29	high_impact	3,56	damaging	0,56	neutral	0,32	deleterious	4,44	24,2	0,38	0,5	neutral	0,3	disease	0,91	disease	0,73	disease	0,64	3	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,76	high_impact	2,05	0,56	0,8	26,2	7,33	N	0,44	N	1	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13703	13703	G	A	MI.22179	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1367	456	R	H	cGc/cAc	3,38	1	0	probably_damaging	1	neutral	0,53	neutral	0,68	neutral	-2,01	deleterious	-4,49	high_impact	3,92	damaging	0,54	damaging	0,21	deleterious	4,64	24,5	0,47	0,55	disease	0,87	disease	0,85	disease	0,77	disease	0,83	7	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,26	high_impact	2,38	0,84	0,9	26,2	7,33	P	0,55	P	1	disease_causing	1	0,23	.	.	.	.	.	.	COSM1497295	.	.	.	.	.	.	.	.
chrM	6066	6066	A	G	MI.2218	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	163	55	N	D	Aac/Gac	-3,81	0	0	benign	0,34	deleterious	0	neutral	2,68	neutral	2,15	deleterious	-3,14	high_impact	4,62	damaging	0,45	damaging	0,14	deleterious	3,63	23,2	0,4	0,55	disease	0,88	disease	0,87	disease	0,75	disease	0,84	7	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,52	medium_impact	-0,49	low_impact	-1,48	high_impact	3,17	0,62	0,9	3,12	7,34	N	0,51	P	0,92	polymorphism	0,96	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13705	13705	C	G	MI.22180	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1369	457	L	V	Ctg/Gtg	-10,15	0	0	probably_damaging	1	neutral	0,5	neutral	-0,95	deleterious	-6,21	deleterious	-2,7	high_impact	3,94	damaging	0,33	damaging	0,04	deleterious	3,53	23,1	0,45	0,55	disease	0,75	disease	0,7	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,23	high_impact	2,4	0,84	0,9	28,52	7,2	N	0,34	N	0,81	polymorphism	0,81	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13705	13705	C	A	MI.22181	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1369	457	L	M	Ctg/Atg	-10,15	0	0	probably_damaging	1	neutral	0,31	neutral	-0,91	deleterious	-5,47	neutral	-1,8	high_impact	3,94	damaging	0,4	damaging	0,05	deleterious	3,87	23,5	0,34	0,5	disease	0,88	disease	0,7	disease	0,67	disease	0,75	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,04	high_impact	2,4	0,76	0,85	28,52	7,2	N	0,34	N	0,89	polymorphism	0,85	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13706	13706	T	A	MI.22182	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1370	457	L	Q	cTg/cAg	-0,52	0	0	probably_damaging	1	neutral	0,3	neutral	-1	deleterious	-9,41	deleterious	-5,39	high_impact	3,94	damaging	0,37	damaging	0,03	deleterious	4,3	24	0,15	0,4	disease	0,88	disease	0,88	disease	0,69	disease	0,79	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,03	high_impact	2,4	0,71	0,85	28,52	7,2	N	0,41	N	0,98	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13706	13706	T	C	MI.22183	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1370	457	L	P	cTg/cCg	-0,52	0	0	probably_damaging	1	neutral	0,27	neutral	-1	deleterious	-9,98	deleterious	-6,29	high_impact	3,94	damaging	0,34	damaging	0,04	deleterious	4,01	23,6	0,15	0,4	disease	0,88	disease	0,86	disease	0,8	disease	0,85	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	-0,01	high_impact	2,4	0,66	0,8	28,52	7,2	N	0,48	N	0,99	disease_causing	0,99	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13706	13706	T	G	MI.22184	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1370	457	L	R	cTg/cGg	-0,52	0	0	probably_damaging	1	neutral	0,43	neutral	-1	deleterious	-9,58	deleterious	-5,39	high_impact	3,94	damaging	0,41	damaging	0,04	deleterious	4,3	24	0,13	0,4	disease	0,93	disease	0,91	disease	0,79	disease	0,88	8	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,17	high_impact	2,4	0,46	0,8	28,52	7,2	N	0,44	N	1	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13708	13708	G	T	MI.22185	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1372	458	A	S	Gca/Tca	-11,75	0	0,21	benign	0,4	neutral	0,5	neutral	0,73	neutral	-2,8	neutral	-1,51	medium_impact	2,96	damaging	0,54	neutral	0,7	deleterious	1,87	15,43	0,37	0,5	disease	0,74	disease	0,82	neutral	0,45	disease	0,58	2	neutral	0,44	deleterious	0,55	neutral	-3	neutral	0,26	medium_impact	-0,58	medium_impact	0,23	medium_impact	1,5	0,72	0,85	24,54	22,73	N	0,34	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13708	13708	G	A	MI.22186	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1372	458	A	T	Gca/Aca	-11,75	0	0,21	benign	0,02	neutral	0,48	neutral	0,67	deleterious	-3,04	neutral	-1,5	low_impact	1,48	damaging	0,29	neutral	0,74	neutral	1,25	12,03	0,37	0,5	disease	0,63	disease	0,73	neutral	0,44	disease	0,53	1	neutral	0,5	deleterious	0,73	neutral	-6	neutral	0,21	medium_impact	0,86	medium_impact	0,21	medium_impact	0,15	0,68	0,85	24,54	22,73	P	0,76	P	0,01	polymorphism	1	0,03	rs28359178	other	Leber's_optic_atrophy	RCV000010336.4	MedGen:OMIM:SNOMED_CT	acute leukemia platelets, leukocytes & bone marrow, breast tumor	.	.	.	G13708A	LHON/Increased MS risk/higher freq in PD-ADS	+	-	P.M.-haplogroup J marker	45
chrM	13708	13708	G	C	MI.22187	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1372	458	A	P	Gca/Cca	-11,75	0	0,21	possibly_damaging	0,86	neutral	0,26	neutral	0,62	deleterious	-5,29	deleterious	-2,87	high_impact	3,65	damaging	0,54	neutral	0,4	deleterious	2,05	16,53	0,11	0,4	disease	0,84	disease	0,94	disease	0,69	disease	0,78	6	neutral	0,89	neutral	0,2	deleterious	1	neutral	0,38	low_impact	-1,5	medium_impact	-0,02	high_impact	2,13	0,74	0,85	24,54	22,73	N	0,33	N	0,62	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13709	13709	C	T	MI.22188	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1373	458	A	V	gCa/gTa	0,4	0	0	benign	0,4	neutral	0,56	neutral	0,74	neutral	-2,26	neutral	-0,74	medium_impact	2,85	damaging	0,51	neutral	0,67	deleterious	2,62	20,3	0,37	0,5	neutral	0,47	disease	0,86	neutral	0,45	disease	0,66	3	neutral	0,39	deleterious	0,58	neutral	-3	neutral	0,21	medium_impact	-0,58	medium_impact	0,29	medium_impact	1,4	0,73	0,85	24,54	22,73	N	0,43	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13709	13709	C	A	MI.22189	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1373	458	A	E	gCa/gAa	0,4	0	0	possibly_damaging	0,73	neutral	0,37	neutral	0,63	deleterious	-4,46	deleterious	-2,87	high_impact	3,65	damaging	0,56	neutral	0,5	deleterious	2,6	20,2	0,14	0,4	disease	0,89	disease	0,92	disease	0,67	disease	0,81	6	neutral	0,75	neutral	0,32	deleterious	1	neutral	0,32	low_impact	-1,16	medium_impact	0,11	high_impact	2,13	0,59	0,8	24,54	22,73	N	0,32	N	0,57	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6066	6066	A	C	MI.2219	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	163	55	N	H	Aac/Cac	-3,81	0	0	probably_damaging	0,93	deleterious	0	neutral	2,57	neutral	-1,91	deleterious	-3,14	high_impact	4,62	damaging	0,52	damaging	0,08	deleterious	2,89	21,8	0,25	0,55	disease	0,81	disease	0,9	disease	0,66	disease	0,77	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,86	low_impact	-1,81	low_impact	-1,48	high_impact	3,17	0,61	0,9	3,12	7,34	N	0,42	N	0,83	polymorphism	0,92	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13709	13709	C	G	MI.22190	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1373	458	A	G	gCa/gGa	0,4	0	0	possibly_damaging	0,61	neutral	0,41	neutral	0,67	deleterious	-3,26	deleterious	-2,92	medium_impact	3,31	damaging	0,55	neutral	0,61	deleterious	2,11	16,95	0,25	0,45	disease	0,75	disease	0,81	disease	0,54	disease	0,58	2	neutral	0,64	neutral	0,4	NA	0	neutral	0,23	medium_impact	-0,93	medium_impact	0,15	medium_impact	1,82	0,75	0,85	24,54	22,73	N	0,34	N	0,5	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13711	13711	G	A	MI.22191	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1375	459	A	T	Gcc/Acc	-6,25	0	0	benign	0,02	neutral	0,42	neutral	0,97	neutral	-0,52	neutral	-0,38	neutral_impact	-0,3	neutral	0,88	neutral	0,81	neutral	1,23	11,9	0,55	0,6	disease	0,62	neutral	0,39	neutral	0,35	disease	0,61	2	neutral	0,56	deleterious	0,7	neutral	-6	neutral	0,18	medium_impact	0,86	medium_impact	0,16	low_impact	-1,48	0,73	0,85	21,06	13,68	N	0,3	N	0,06	polymorphism	1	0,01	rs879489195	.	.	.	.	.	COSM1132235	.	.	.	.	.	.	.	.
chrM	13711	13711	G	T	MI.22192	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1375	459	A	S	Gcc/Tcc	-6,25	0	0	benign	0,18	neutral	0,45	neutral	0,96	neutral	-0,61	neutral	-0,96	neutral_impact	0,7	neutral	0,82	neutral	0,77	deleterious	1,93	15,77	0,41	0,5	disease	0,67	disease	0,51	neutral	0,43	neutral	0,5	0	neutral	0,46	deleterious	0,64	neutral	-6	neutral	0,3	medium_impact	-0,12	medium_impact	0,18	medium_impact	-0,56	0,88	0,9	21,06	13,68	N	0,29	N	0,16	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13711	13711	G	C	MI.22193	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1375	459	A	P	Gcc/Ccc	-6,25	0	0	possibly_damaging	0,62	neutral	0,28	neutral	0,9	neutral	-2,8	neutral	-1,97	low_impact	1,24	neutral	0,66	neutral	0,4	deleterious	3,53	23,1	0,13	0,4	disease	0,87	disease	0,88	disease	0,6	disease	0,84	7	neutral	0,74	neutral	0,33	neutral	-3	deleterious	0,66	medium_impact	-0,95	medium_impact	0,01	medium_impact	-0,07	0,84	0,9	21,06	13,68	N	0,27	N	0,36	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13712	13712	C	G	MI.22194	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1376	459	A	G	gCc/gGc	-3,96	0	0	benign	0,24	neutral	0,38	neutral	0,91	neutral	-2,26	deleterious	-2,56	low_impact	1,24	neutral	0,77	neutral	0,74	deleterious	2,21	17,55	0,24	0,45	disease	0,53	disease	0,52	neutral	0,45	neutral	0,5	0	neutral	0,54	deleterious	0,57	neutral	-6	neutral	0,31	medium_impact	-0,27	medium_impact	0,12	medium_impact	-0,07	0,76	0,85	21,06	13,68	N	0,3	N	0,34	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13712	13712	C	T	MI.22195	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1376	459	A	V	gCc/gTc	-3,96	0	0	benign	0,01	neutral	0,57	neutral	1,04	neutral	0,42	neutral	1,72	neutral_impact	-0,83	neutral	0,89	neutral	0,97	neutral	1,08	11,09	0,41	0,5	neutral	0,33	disease	0,51	neutral	0,25	neutral	0,44	1	neutral	0,42	deleterious	0,78	neutral	-6	neutral	0,14	medium_impact	1,15	medium_impact	0,3	low_impact	-1,96	0,73	0,85	21,06	13,68	N	0,26	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13712	13712	C	A	MI.22196	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1376	459	A	D	gCc/gAc	-3,96	0	0	possibly_damaging	0,55	neutral	0,22	neutral	0,9	deleterious	-3,4	deleterious	-2,51	low_impact	1,24	neutral	0,65	neutral	0,47	deleterious	2,96	22,1	0,13	0,4	disease	0,91	disease	0,83	disease	0,6	disease	0,84	7	neutral	0,77	neutral	0,34	neutral	-3	deleterious	0,54	medium_impact	-0,83	medium_impact	-0,07	medium_impact	-0,07	0,73	0,85	21,06	13,68	N	0,27	N	0,37	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13714	13714	G	T	MI.22197	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1378	460	G	W	Gga/Tga	-13,12	0	0	probably_damaging	1	neutral	0,2	neutral	0,56	deleterious	-4,64	deleterious	-7,16	high_impact	3,82	damaging	0,46	damaging	0,24	deleterious	4,55	24,3	0,14	0,4	disease	0,93	disease	0,94	disease	0,77	disease	0,88	8	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,1	high_impact	2,29	0,51	0,8	11,77	7,47	N	0,39	N	1	polymorphism	0,98	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13714	13714	G	C	MI.22198	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1378	460	G	R	Gga/Cga	-13,12	0	0	probably_damaging	1	neutral	0,39	neutral	0,56	deleterious	-4,27	deleterious	-7,15	high_impact	3,82	damaging	0,44	damaging	0,25	deleterious	4,09	23,7	0,1	0,4	disease	0,86	disease	0,94	disease	0,83	disease	0,91	8	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,13	high_impact	2,29	0,64	0,8	11,77	7,47	N	0,49	N	1	polymorphism	0,99	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13715	13715	G	T	MI.22199	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1379	460	G	V	gGa/gTa	5,9	1	0	probably_damaging	0,99	neutral	0,57	neutral	0,67	neutral	-2,02	deleterious	-8,05	high_impact	3,82	damaging	0,39	neutral	0,29	deleterious	3,87	23,5	0,15	0,45	disease	0,52	disease	0,93	disease	0,75	disease	0,81	6	deleterious	0,98	neutral	0,29	deleterious	2	deleterious	0,84	low_impact	-2,64	medium_impact	0,3	high_impact	2,29	0,59	0,8	11,77	7,47	P	0,71	P	0,98	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8631	8631	A	T	MI.222	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	105	35	K	N	aaA/aaT	-0,8	0	0	benign	0,01	neutral	0,43	neutral	4,35	neutral	-1,03	neutral	0,49	neutral_impact	-0,7	neutral	0,88	neutral	0,95	neutral	-0,98	0,02	0,65	0,7	neutral	0,34	neutral	0,14	neutral	0,25	neutral	0,22	6	neutral	0,56	deleterious	0,71	neutral	-6	neutral	0,14	medium_impact	1,14	medium_impact	0,22	low_impact	-1,7	0,6	0,9	20,35	18,29	N	0,46	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6066	6066	A	T	MI.2220	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	163	55	N	Y	Aac/Tac	-3,81	0	0	probably_damaging	0,99	deleterious	0	neutral	2,68	deleterious	-3,03	deleterious	-5,03	high_impact	4,47	damaging	0,52	damaging	0,1	deleterious	3,44	23	0,18	0,55	neutral	0,43	disease	0,94	disease	0,62	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,64	low_impact	-1,48	high_impact	3,03	0,57	0,9	3,12	7,34	N	0,38	N	0,93	polymorphism	0,73	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13715	13715	G	C	MI.22200	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1379	460	G	A	gGa/gCa	5,9	1	0	possibly_damaging	0,56	neutral	0,54	neutral	0,63	neutral	-2,56	deleterious	-5,36	medium_impact	2,12	damaging	0,53	neutral	0,63	deleterious	3,23	22,8	0,25	0,45	disease	0,55	disease	0,77	disease	0,64	disease	0,53	1	neutral	0,52	deleterious	0,49	NA	0	deleterious	0,81	medium_impact	-0,85	medium_impact	0,27	medium_impact	0,73	0,56	0,8	11,77	7,47	N	0,49	N	0,79	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13715	13715	G	A	MI.22201	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1379	460	G	E	gGa/gAa	5,9	1	0	probably_damaging	0,99	neutral	0,28	neutral	0,56	deleterious	-4,31	deleterious	-7,15	high_impact	3,82	damaging	0,43	damaging	0,28	deleterious	4	23,6	0,13	0,4	disease	0,88	disease	0,93	disease	0,83	disease	0,88	8	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,89	low_impact	-2,64	medium_impact	0,01	high_impact	2,29	0,55	0,8	11,77	7,47	P	0,75	P	1	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13717	13717	A	C	MI.22202	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1381	461	S	R	Agc/Cgc	-1,44	0	0	probably_damaging	1	neutral	0,35	neutral	0,31	deleterious	-5,41	deleterious	-4,49	high_impact	3,88	neutral	0,6	neutral	0,41	deleterious	4,04	23,7	0,11	0,4	disease	0,89	disease	0,93	disease	0,8	disease	0,9	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,08	high_impact	2,34	0,76	0,85	13,6	7,11	N	0,46	N	0,99	polymorphism	0,56	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13717	13717	A	G	MI.22203	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1381	461	S	G	Agc/Ggc	-1,44	0	0	probably_damaging	1	neutral	0,36	neutral	0,35	deleterious	-4,03	deleterious	-3,59	high_impact	3,88	damaging	0,59	neutral	0,53	deleterious	3,75	23,3	0,27	0,45	disease	0,9	disease	0,8	disease	0,64	disease	0,77	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,1	high_impact	2,34	0,75	0,85	13,6	7,11	N	0,35	N	0,86	polymorphism	0,87	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13717	13717	A	T	MI.22204	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1381	461	S	C	Agc/Tgc	-1,44	0	0	probably_damaging	1	neutral	0,18	neutral	0,3	deleterious	-6,22	deleterious	-4,49	high_impact	3,88	neutral	0,61	neutral	0,41	deleterious	3,65	23,2	0,19	0,45	disease	0,58	disease	0,89	disease	0,68	disease	0,75	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	-0,13	high_impact	2,34	0,81	0,85	13,6	7,11	N	0,37	N	0,99	polymorphism	0,6	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13718	13718	G	T	MI.22205	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1382	461	S	I	aGc/aTc	5,44	1	0	probably_damaging	1	neutral	0,44	neutral	0,31	deleterious	-5,43	deleterious	-5,39	high_impact	3,88	damaging	0,57	neutral	0,52	deleterious	4,23	23,9	0,17	0,45	disease	0,55	disease	0,94	disease	0,7	disease	0,82	6	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,18	high_impact	2,34	0,84	0,9	13,6	7,11	N	0,51	P	0,99	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13718	13718	G	C	MI.22206	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1382	461	S	T	aGc/aCc	5,44	1	0	probably_damaging	1	neutral	0,4	neutral	0,45	neutral	-2,44	deleterious	-2,69	medium_impact	2,44	neutral	0,62	neutral	0,63	deleterious	3,5	23,1	0,29	0,45	disease	0,56	disease	0,73	disease	0,62	disease	0,55	1	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,14	medium_impact	1,03	0,87	0,9	13,6	7,11	N	0,45	N	0,71	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13718	13718	G	A	MI.22207	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1382	461	S	N	aGc/aAc	5,44	1	0	probably_damaging	1	neutral	0,32	neutral	0,32	deleterious	-5,15	deleterious	-2,69	high_impact	3,88	damaging	0,55	neutral	0,45	deleterious	3,8	23,4	0,46	0,55	disease	0,84	disease	0,88	disease	0,7	disease	0,78	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,05	high_impact	2,34	0,56	0,8	13,6	7,11	P	0,58	P	0,87	disease_causing	1	0,17	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	13720	13720	C	A	MI.22208	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1384	462	L	M	Cta/Ata	-1,89	0	0	benign	0,29	neutral	0,26	neutral	0,81	neutral	-2,03	neutral	-0,9	neutral_impact	0,34	neutral	0,79	neutral	0,83	deleterious	3,78	23,4	0,35	0,5	disease	0,79	disease	0,54	neutral	0,3	disease	0,57	1	neutral	0,69	deleterious	0,49	neutral	-6	deleterious	0,77	medium_impact	-0,38	medium_impact	-0,02	medium_impact	-0,89	0,78	0,85	13,1	13,73	N	0,32	N	0,06	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13720	13720	C	G	MI.22209	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1384	462	L	V	Cta/Gta	-1,89	0	0	possibly_damaging	0,49	neutral	0,54	neutral	1,06	neutral	0,34	neutral	0,62	neutral_impact	0,03	neutral	0,83	neutral	0,95	deleterious	3,48	23,1	0,34	0,5	neutral	0,32	disease	0,57	neutral	0,31	neutral	0,44	1	neutral	0,47	deleterious	0,53	neutral	-3	deleterious	0,7	medium_impact	-0,73	medium_impact	0,27	low_impact	-1,18	0,7	0,85	13,1	13,73	N	0,25	N	0,11	polymorphism	0,99	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6067	6067	A	T	MI.2221	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	164	55	N	I	aAc/aTc	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,55	neutral	-2,93	deleterious	-5,66	high_impact	4,82	damaging	0,52	damaging	0,09	deleterious	3,82	23,4	0,17	0,55	disease	0,8	disease	0,95	disease	0,67	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,64	low_impact	-1,48	high_impact	3,35	0,51	0,9	3,12	7,34	P	0,66	P	0,98	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13721	13721	T	A	MI.22210	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1385	462	L	Q	cTa/cAa	1,08	0,42	0	probably_damaging	0,96	neutral	0,29	neutral	0,76	deleterious	-5,16	deleterious	-4,49	low_impact	1,94	neutral	0,69	neutral	0,61	deleterious	4,2	23,9	0,18	0,45	disease	0,88	disease	0,81	disease	0,57	disease	0,81	6	neutral	0,97	neutral	0,17	neutral	-2	deleterious	0,85	low_impact	-2,06	medium_impact	0,02	medium_impact	0,57	0,74	0,85	13,1	13,73	N	0,29	N	0,77	polymorphism	0,98	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13721	13721	T	G	MI.22211	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1385	462	L	R	cTa/cGa	1,08	0,42	0	probably_damaging	0,95	neutral	0,42	neutral	0,76	deleterious	-5,06	deleterious	-4,52	low_impact	1,94	neutral	0,65	neutral	0,51	deleterious	4,33	24	0,15	0,4	disease	0,87	disease	0,94	disease	0,7	disease	0,86	7	neutral	0,95	neutral	0,24	neutral	-2	deleterious	0,91	low_impact	-1,96	medium_impact	0,16	medium_impact	0,57	0,64	0,8	13,1	13,73	N	0,27	N	0,78	polymorphism	0,98	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13721	13721	T	C	MI.22212	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1385	462	L	P	cTa/cCa	1,08	0,42	0	probably_damaging	0,98	neutral	0,23	neutral	0,75	deleterious	-5,38	deleterious	-4,59	low_impact	1,94	damaging	0,53	neutral	0,44	deleterious	4,04	23,7	0,17	0,45	disease	0,9	disease	0,93	disease	0,71	disease	0,86	7	deleterious	0,98	neutral	0,13	neutral	-2	deleterious	0,93	low_impact	-2,35	medium_impact	-0,06	medium_impact	0,57	0,68	0,85	13,1	13,73	N	0,31	N	0,88	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13723	13723	T	G	MI.22213	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1387	463	F	V	Ttc/Gtc	-7,17	0	0	benign	0,01	neutral	0,54	neutral	1,04	neutral	0,27	deleterious	-4,04	low_impact	1,32	neutral	0,83	neutral	0,83	deleterious	0,88	9,93	0,3	0,45	neutral	0,45	disease	0,62	neutral	0,4	neutral	0,46	1	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,38	medium_impact	1,15	medium_impact	0,27	medium_impact	0	0,7	0,85	19,24	15,09	N	0,26	N	0,83	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13723	13723	T	A	MI.22214	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1387	463	F	I	Ttc/Atc	-7,17	0	0	benign	0,01	neutral	0,55	neutral	1,11	neutral	0,72	deleterious	-3,23	neutral_impact	0,26	neutral	0,81	neutral	0,9	deleterious	0,59	8,09	0,25	0,45	neutral	0,49	neutral	0,32	neutral	0,31	neutral	0,43	1	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,35	medium_impact	1,15	medium_impact	0,28	medium_impact	-0,97	0,67	0,85	19,24	15,09	N	0,27	N	0,37	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13723	13723	T	C	MI.22215	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1387	463	F	L	Ttc/Ctc	-7,17	0	0	benign	0,01	neutral	1	neutral	1,03	neutral	0,22	deleterious	-3,01	neutral_impact	0,32	neutral	0,85	neutral	0,95	deleterious	0,33	5,99	0,4	0,5	neutral	0,36	neutral	0,5	neutral	0,34	neutral	0,45	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,15	high_impact	1,89	medium_impact	-0,91	0,75	0,85	19,24	15,09	N	0,22	N	0,48	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13724	13724	T	A	MI.22216	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1388	463	F	Y	tTc/tAc	-0,75	0	0	possibly_damaging	0,61	neutral	0,84	neutral	0,84	neutral	-2,59	neutral	-2,13	medium_impact	2,89	neutral	0,75	neutral	0,49	deleterious	4,19	23,8	0,33	0,5	disease	0,8	disease	0,72	disease	0,61	disease	0,74	5	neutral	0,54	deleterious	0,62	NA	0	deleterious	0,66	medium_impact	-0,93	medium_impact	0,63	medium_impact	1,44	0,72	0,85	19,24	15,09	N	0,21	N	0,77	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13724	13724	T	C	MI.22217	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1388	463	F	S	tTc/tCc	-0,75	0	0	possibly_damaging	0,54	neutral	0,43	neutral	0,89	neutral	-1,23	deleterious	-5,51	medium_impact	2,54	neutral	0,84	neutral	0,59	deleterious	4,26	23,9	0,28	0,45	disease	0,79	disease	0,75	disease	0,6	disease	0,72	4	neutral	0,58	neutral	0,45	NA	0	deleterious	0,72	medium_impact	-0,81	medium_impact	0,17	medium_impact	1,12	0,65	0,8	19,24	15,09	N	0,26	N	0,94	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13724	13724	T	G	MI.22218	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1388	463	F	C	tTc/tGc	-0,75	0	0	probably_damaging	0,93	neutral	0,16	neutral	0,83	deleterious	-3,39	deleterious	-5,33	medium_impact	2,89	neutral	0,74	neutral	0,49	deleterious	4,19	23,9	0,27	0,45	disease	0,89	disease	0,86	disease	0,63	disease	0,8	6	neutral	0,96	neutral	0,12	deleterious	1	deleterious	0,8	low_impact	-1,81	medium_impact	-0,17	medium_impact	1,44	0,47	0,8	19,24	15,09	N	0,29	N	0,86	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13725	13725	C	A	MI.22219	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1389	463	F	L	ttC/ttA	3,61	0,34	0,04	benign	0,01	neutral	1	neutral	1,03	neutral	0,22	deleterious	-3,01	neutral_impact	0,32	neutral	0,85	neutral	0,95	neutral	0,98	10,54	0,4	0,5	neutral	0,36	neutral	0,5	neutral	0,34	neutral	0,45	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,15	high_impact	1,89	medium_impact	-0,91	0,75	0,85	19,24	15,09	N	0,29	N	0,48	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6067	6067	A	G	MI.2222	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	164	55	N	S	aAc/aGc	8,69	1	0	benign	0,16	deleterious	0	neutral	2,65	neutral	-0,53	deleterious	-3,14	high_impact	4,62	damaging	0,56	damaging	0,1	deleterious	2,99	22,2	0,47	0,55	disease	0,81	disease	0,89	disease	0,67	disease	0,77	5	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,51	medium_impact	-0,08	low_impact	-1,48	high_impact	3,17	0,55	0,9	3,12	7,34	P	0,54	P	0,79	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13725	13725	C	G	MI.22220	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1389	463	F	L	ttC/ttG	3,61	0,34	0,04	benign	0,01	neutral	1	neutral	1,03	neutral	0,22	deleterious	-3,01	neutral_impact	0,32	neutral	0,85	neutral	0,95	deleterious	0,65	8,47	0,4	0,5	neutral	0,36	neutral	0,5	neutral	0,34	neutral	0,45	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,15	high_impact	1,89	medium_impact	-0,91	0,75	0,85	19,24	15,09	N	0,29	N	0,48	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13726	13726	G	T	MI.22221	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1390	464	A	S	Gca/Tca	-7,17	0	0	possibly_damaging	0,74	neutral	0,44	neutral	0,9	neutral	-0,45	neutral	-2,38	medium_impact	2,03	neutral	0,77	neutral	0,63	deleterious	3,41	23	0,45	0,55	disease	0,7	disease	0,84	neutral	0,43	disease	0,56	1	neutral	0,74	neutral	0,35	NA	0	deleterious	0,61	low_impact	-1,18	medium_impact	0,18	medium_impact	0,65	0,88	0,9	8,96	10,51	N	0,23	N	0,66	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13726	13726	G	C	MI.22222	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1390	464	A	P	Gca/Cca	-7,17	0	0	probably_damaging	0,97	neutral	0,21	neutral	0,62	deleterious	-4,54	deleterious	-4,19	high_impact	3,66	neutral	0,69	neutral	0,35	deleterious	3,92	23,5	0,12	0,4	disease	0,89	disease	0,95	disease	0,76	disease	0,87	7	neutral	0,98	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-2,18	medium_impact	-0,09	high_impact	2,14	0,81	0,85	8,96	10,51	N	0,34	N	0,93	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13726	13726	G	A	MI.22223	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1390	464	A	T	Gca/Aca	-7,17	0	0	benign	0,13	neutral	0,4	neutral	0,69	neutral	-2,29	deleterious	-3,27	medium_impact	2,03	neutral	0,77	neutral	0,68	deleterious	2,38	18,72	0,48	0,55	disease	0,64	disease	0,84	neutral	0,45	disease	0,54	1	neutral	0,53	deleterious	0,64	neutral	-3	neutral	0,3	medium_impact	0,04	medium_impact	0,14	medium_impact	0,65	0,74	0,85	8,96	10,51	N	0,24	N	0,51	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13727	13727	C	T	MI.22224	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1391	464	A	V	gCa/gTa	1,08	0,24	0	benign	0,12	neutral	0,52	neutral	0,64	deleterious	-3,53	deleterious	-3,26	medium_impact	2,56	neutral	0,73	neutral	0,65	deleterious	4,22	23,9	0,34	0,5	neutral	0,45	disease	0,84	disease	0,59	disease	0,54	1	neutral	0,39	deleterious	0,7	neutral	-3	deleterious	0,6	medium_impact	0,08	medium_impact	0,25	medium_impact	1,14	0,8	0,85	8,96	10,51	N	0,3	N	0,62	polymorphism	0,85	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13727	13727	C	A	MI.22225	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1391	464	A	E	gCa/gAa	1,08	0,24	0	possibly_damaging	0,88	neutral	0,27	neutral	0,64	deleterious	-3,45	deleterious	-4,17	high_impact	3,66	neutral	0,68	neutral	0,4	deleterious	4,44	24,2	0,11	0,4	disease	0,88	disease	0,94	disease	0,74	disease	0,85	7	neutral	0,9	neutral	0,2	deleterious	1	deleterious	0,81	low_impact	-1,57	medium_impact	-0,01	high_impact	2,14	0,77	0,85	8,96	10,51	N	0,4	N	0,91	polymorphism	0,76	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13727	13727	C	G	MI.22226	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1391	464	A	G	gCa/gGa	1,08	0,24	0	possibly_damaging	0,8	neutral	0,36	neutral	0,95	neutral	-0,2	deleterious	-3,34	medium_impact	2,56	neutral	0,75	neutral	0,65	deleterious	3,77	23,4	0,28	0,45	disease	0,57	disease	0,85	neutral	0,45	disease	0,54	1	neutral	0,82	neutral	0,28	NA	0	deleterious	0,61	low_impact	-1,32	medium_impact	0,1	medium_impact	1,14	0,71	0,85	8,96	10,51	N	0,28	N	0,7	polymorphism	0,88	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13729	13729	G	T	MI.22227	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1393	465	G	W	Gga/Tga	-6,71	0	0	probably_damaging	1	neutral	0,27	deleterious	-2,89	deleterious	-13,96	deleterious	-7,19	high_impact	3,94	damaging	0,27	damaging	0,02	deleterious	4,54	24,3	0,16	0,45	disease	0,93	disease	0,93	disease	0,81	disease	0,88	8	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,01	high_impact	2,4	0,33	0,8	23,55	7,09	P	0,48	N	1	disease_causing	0,95	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13729	13729	G	C	MI.22228	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1393	465	G	R	Gga/Cga	-6,71	0	0	probably_damaging	1	neutral	0,34	deleterious	-2,88	deleterious	-12,09	deleterious	-7,19	high_impact	3,94	damaging	0,3	damaging	0,02	deleterious	4,08	23,7	0,14	0,4	disease	0,97	disease	0,93	disease	0,85	disease	0,86	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,92	low_impact	-3,6	medium_impact	0,07	high_impact	2,4	0,68	0,85	23,55	7,09	N	0,45	N	1	disease_causing	0,92	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13730	13730	G	C	MI.22229	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1394	465	G	A	gGa/gCa	9,11	1	0	probably_damaging	1	neutral	0,54	deleterious	-2,87	deleterious	-10,35	deleterious	-5,39	high_impact	3,94	damaging	0,36	damaging	0,04	deleterious	3,21	22,7	0,25	0,45	disease	0,84	disease	0,79	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,27	high_impact	2,4	0,49	0,8	23,55	7,09	P	0,59	P	0,79	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6067	6067	A	C	MI.2223	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	164	55	N	T	aAc/aCc	8,69	1	0	possibly_damaging	0,54	deleterious	0	neutral	2,59	neutral	-1,17	deleterious	-3,77	high_impact	5,17	damaging	0,54	damaging	0,1	deleterious	3,26	22,8	0,32	0,55	disease	0,82	disease	0,91	disease	0,68	disease	0,77	5	deleterious	1	neutral	0,23	deleterious	5	deleterious	0,73	medium_impact	-0,82	low_impact	-1,48	high_impact	3,68	0,6	0,9	3,12	7,34	P	0,68	P	0,59	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13730	13730	G	T	MI.22230	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1394	465	G	V	gGa/gTa	9,11	1	0	probably_damaging	1	neutral	0,55	deleterious	-2,88	deleterious	-12	deleterious	-8,09	high_impact	3,94	damaging	0,28	damaging	0,02	deleterious	3,89	23,5	0,16	0,45	disease	0,94	disease	0,92	disease	0,79	disease	0,87	7	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,28	high_impact	2,4	0,5	0,8	23,55	7,09	P	0,67	P	0,98	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13730	13730	G	A	MI.22231	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1394	465	G	E	gGa/gAa	9,11	1	0	probably_damaging	1	neutral	0,27	deleterious	-2,88	deleterious	-11,67	deleterious	-7,19	high_impact	3,94	damaging	0,19	damaging	0,01	deleterious	4,05	23,7	0,17	0,45	disease	0,96	disease	0,92	disease	0,85	disease	0,86	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,01	high_impact	2,4	0,59	0,8	23,55	7,09	P	0,83	P	1	disease_causing_automatic	1	0,51	rs387906425	Pathogenic	Leber's_optic_atrophy	RCV000010337.4	MedGen:OMIM:SNOMED_CT	.	.	.	.	G13730A	LHON	-	+	Reported	7
chrM	13732	13732	T	A	MI.22232	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1396	466	F	I	Ttt/Att	-8,54	0	0	probably_damaging	1	neutral	0,4	neutral	0,96	neutral	-0,92	deleterious	-4,98	medium_impact	2,06	neutral	0,83	neutral	0,69	deleterious	4,6	24,4	0,27	0,45	neutral	0,39	disease	0,7	disease	0,53	disease	0,61	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,71	low_impact	-3,6	medium_impact	0,14	medium_impact	0,68	0,55	0,8	5,47	11,56	N	0,32	N	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13732	13732	T	G	MI.22233	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1396	466	F	V	Ttt/Gtt	-8,54	0	0	probably_damaging	1	neutral	0,5	neutral	0,98	neutral	-0,77	deleterious	-5,67	medium_impact	2,68	neutral	0,84	neutral	0,61	deleterious	4,28	24	0,32	0,5	neutral	0,34	disease	0,72	disease	0,62	disease	0,57	1	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,67	low_impact	-3,6	medium_impact	0,23	medium_impact	1,25	0,44	0,8	5,47	11,56	N	0,27	N	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13732	13732	T	C	MI.22234	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1396	466	F	L	Ttt/Ctt	-8,54	0	0	probably_damaging	1	neutral	0,65	neutral	1,1	neutral	-0,21	deleterious	-4,98	neutral_impact	0,38	neutral	0,74	neutral	0,82	deleterious	2	16,2	0,38	0,5	neutral	0,29	neutral	0,22	neutral	0,3	neutral	0,4	2	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,63	low_impact	-3,6	medium_impact	0,38	medium_impact	-0,86	0,59	0,8	5,47	11,56	N	0,3	N	0,78	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13733	13733	T	A	MI.22235	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1397	466	F	Y	tTt/tAt	0,17	0	0	probably_damaging	1	neutral	1	neutral	0,9	neutral	-1,63	neutral	-1,25	low_impact	1,49	neutral	0,86	neutral	0,97	deleterious	3,25	22,8	0,4	0,5	disease	0,6	neutral	0,48	neutral	0,41	disease	0,59	2	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,71	low_impact	-3,6	high_impact	1,89	medium_impact	0,16	0,65	0,8	5,47	11,56	N	0,24	N	0,12	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13733	13733	T	C	MI.22236	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1397	466	F	S	tTt/tCt	0,17	0	0	probably_damaging	1	neutral	0,4	neutral	1,15	neutral	-1,98	deleterious	-6,57	low_impact	1,88	neutral	0,81	neutral	0,85	deleterious	4,46	24,2	0,33	0,5	disease	0,55	disease	0,71	disease	0,61	disease	0,59	2	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	0,14	medium_impact	0,51	0,52	0,8	5,47	11,56	N	0,26	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13733	13733	T	G	MI.22237	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1397	466	F	C	tTt/tGt	0,17	0	0	probably_damaging	1	neutral	0,18	neutral	0,9	deleterious	-3,7	deleterious	-6,57	medium_impact	3,03	neutral	0,69	neutral	0,46	deleterious	4,32	24	0,23	0,45	disease	0,69	disease	0,84	disease	0,64	disease	0,79	6	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	-0,13	medium_impact	1,57	0,26	0,8	5,47	11,56	N	0,3	N	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13734	13734	T	G	MI.22238	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1398	466	F	L	ttT/ttG	1,31	0	0,02	probably_damaging	1	neutral	0,65	neutral	1,1	neutral	-0,21	deleterious	-4,98	neutral_impact	0,38	neutral	0,74	neutral	0,82	deleterious	2,23	17,68	0,38	0,5	neutral	0,29	neutral	0,22	neutral	0,3	neutral	0,4	2	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,63	low_impact	-3,6	medium_impact	0,38	medium_impact	-0,86	0,59	0,8	5,47	11,56	N	0,3	N	0,78	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13734	13734	T	A	MI.22239	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1398	466	F	L	ttT/ttA	1,31	0	0,02	probably_damaging	1	neutral	0,65	neutral	1,1	neutral	-0,21	deleterious	-4,98	neutral_impact	0,38	neutral	0,74	neutral	0,82	deleterious	2,35	18,52	0,38	0,5	neutral	0,29	neutral	0,22	neutral	0,3	neutral	0,4	2	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,63	low_impact	-3,6	medium_impact	0,38	medium_impact	-0,86	0,59	0,8	5,47	11,56	N	0,32	N	0,78	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6068	6068	C	A	MI.2224	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	165	55	N	K	aaC/aaA	8,69	1	0	benign	0,34	deleterious	0	neutral	2,61	neutral	-0,49	deleterious	-3,77	high_impact	4,82	damaging	0,43	damaging	0,12	deleterious	4,36	24,1	0,33	0,55	disease	0,82	disease	0,93	disease	0,69	disease	0,78	6	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,55	medium_impact	-0,49	low_impact	-1,48	high_impact	3,35	0,73	0,9	3,12	7,34	P	0,73	P	0,92	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13735	13735	C	T	MI.22240	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1399	467	L	F	Ctc/Ttc	-3,96	0	0	benign	0,05	neutral	0,7	neutral	0,88	neutral	-0,83	neutral	-1,52	medium_impact	2,37	neutral	0,89	neutral	0,96	deleterious	0,84	9,68	0,43	0,55	disease	0,56	disease	0,66	neutral	0,42	disease	0,5	0	neutral	0,23	deleterious	0,83	neutral	-3	neutral	0,22	medium_impact	0,47	medium_impact	0,44	medium_impact	0,96	0,62	0,8	11,77	13,66	N	0,24	N	0,14	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13735	13735	C	A	MI.22241	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1399	467	L	I	Ctc/Atc	-3,96	0	0	benign	0,05	neutral	0,4	neutral	0,91	neutral	-0,58	neutral	-0,38	low_impact	0,92	neutral	0,83	neutral	0,99	deleterious	0,08	3,39	0,42	0,55	neutral	0,42	neutral	0,25	neutral	0,35	neutral	0,44	1	neutral	0,56	deleterious	0,68	neutral	-6	neutral	0,39	medium_impact	0,47	medium_impact	0,14	medium_impact	-0,36	0,66	0,8	11,77	13,66	N	0,41	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13735	13735	C	G	MI.22242	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1399	467	L	V	Ctc/Gtc	-3,96	0	0	benign	0,08	neutral	0,5	neutral	0,88	neutral	-0,78	neutral	-1,22	low_impact	1,75	neutral	0,85	neutral	0,94	deleterious	0,71	8,87	0,4	0,5	disease	0,51	disease	0,5	neutral	0,43	neutral	0,47	1	neutral	0,43	deleterious	0,71	neutral	-6	neutral	0,41	medium_impact	0,26	medium_impact	0,23	medium_impact	0,4	0,65	0,8	11,77	13,66	N	0,29	N	0,19	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13736	13736	T	G	MI.22243	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1400	467	L	R	cTc/cGc	-14,73	0	0	probably_damaging	0,92	neutral	0,35	neutral	0,73	deleterious	-3,71	deleterious	-4,54	medium_impact	3,41	neutral	0,65	neutral	0,44	deleterious	4,22	23,9	0,14	0,4	disease	0,87	disease	0,89	disease	0,75	disease	0,85	7	neutral	0,92	neutral	0,22	deleterious	1	deleterious	0,86	low_impact	-1,75	medium_impact	0,08	medium_impact	1,91	0,67	0,85	11,77	13,66	N	0,36	N	0,85	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13736	13736	T	A	MI.22244	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1400	467	L	H	cTc/cAc	-14,73	0	0	probably_damaging	0,96	neutral	0,54	neutral	0,72	deleterious	-4,24	deleterious	-4,72	medium_impact	3,41	neutral	0,71	neutral	0,5	deleterious	4,1	23,7	0,18	0,45	disease	0,8	disease	0,81	disease	0,72	disease	0,77	5	neutral	0,96	neutral	0,29	deleterious	1	deleterious	0,81	low_impact	-2,06	medium_impact	0,27	medium_impact	1,91	0,65	0,8	11,77	13,66	N	0,26	N	0,79	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13736	13736	T	C	MI.22245	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1400	467	L	P	cTc/cCc	-14,73	0	0	probably_damaging	0,94	neutral	0,2	neutral	0,72	deleterious	-4,29	deleterious	-5,16	medium_impact	3,41	damaging	0,58	neutral	0,4	deleterious	3,96	23,6	0,13	0,4	disease	0,91	disease	0,89	disease	0,75	disease	0,84	7	neutral	0,96	neutral	0,13	deleterious	1	deleterious	0,88	low_impact	-1,88	medium_impact	-0,1	medium_impact	1,91	0,47	0,8	11,77	13,66	N	0,34	N	0,91	polymorphism	0,79	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13738	13738	A	G	MI.22246	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1402	468	I	V	Att/Gtt	-6,94	0	0	probably_damaging	1	neutral	0,52	neutral	0,73	neutral	-2,21	neutral	-0,86	medium_impact	2,77	neutral	0,78	damaging	0,28	deleterious	3,17	22,7	0,63	0,65	disease	0,62	neutral	0,4	disease	0,56	disease	0,61	2	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,65	low_impact	-3,6	medium_impact	0,25	medium_impact	1,33	0,5	0,8	13,27	13,52	N	0,26	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13738	13738	A	C	MI.22247	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1402	468	I	L	Att/Ctt	-6,94	0	0	probably_damaging	1	neutral	0,94	neutral	1,36	neutral	1,21	neutral	-0,83	neutral_impact	0,43	neutral	0,8	neutral	0,92	deleterious	2,33	18,38	0,45	0,55	neutral	0,49	neutral	0,36	neutral	0,39	neutral	0,39	2	deleterious	1	deleterious	0,47	neutral	-2	deleterious	0,65	low_impact	-3,6	medium_impact	0,89	medium_impact	-0,81	0,72	0,85	13,27	13,52	N	0,24	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13738	13738	A	T	MI.22248	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1402	468	I	F	Att/Ttt	-6,94	0	0	probably_damaging	1	neutral	0,77	neutral	0,81	neutral	-1,17	deleterious	-3,06	medium_impact	2,34	neutral	0,77	damaging	0,17	deleterious	3,89	23,5	0,49	0,55	disease	0,59	disease	0,76	disease	0,59	disease	0,57	1	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,52	medium_impact	0,94	0,74	0,85	13,27	13,52	N	0,15	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13739	13739	T	G	MI.22249	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1403	468	I	S	aTt/aGt	0,63	0,13	0	probably_damaging	1	neutral	0,57	neutral	0,67	deleterious	-4,42	deleterious	-4,83	medium_impact	3,31	neutral	0,73	damaging	0,14	deleterious	4,39	24,1	0,27	0,45	disease	0,68	disease	0,85	disease	0,65	disease	0,74	5	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,3	medium_impact	1,82	0,56	0,8	13,27	13,52	N	0,25	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6068	6068	C	G	MI.2225	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	165	55	N	K	aaC/aaG	8,69	1	0	benign	0,34	deleterious	0	neutral	2,61	neutral	-0,49	deleterious	-3,77	high_impact	4,82	damaging	0,43	damaging	0,12	deleterious	3,85	23,4	0,33	0,55	disease	0,82	disease	0,93	disease	0,69	disease	0,78	6	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,55	medium_impact	-0,49	low_impact	-1,48	high_impact	3,35	0,73	0,9	3,12	7,34	P	0,73	P	0,92	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13739	13739	T	A	MI.22250	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1403	468	I	N	aTt/aAt	0,63	0,13	0	probably_damaging	1	neutral	0,29	neutral	0,65	deleterious	-5,61	deleterious	-5,72	medium_impact	3,31	neutral	0,68	damaging	0,11	deleterious	4,55	24,4	0,3	0,45	disease	0,71	disease	0,84	disease	0,67	disease	0,75	5	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,02	medium_impact	1,82	0,61	0,8	13,27	13,52	N	0,3	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13739	13739	T	C	MI.22251	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1403	468	I	T	aTt/aCt	0,63	0,13	0	probably_damaging	1	neutral	0,46	neutral	0,7	deleterious	-3	deleterious	-3,96	low_impact	1,87	neutral	0,76	damaging	0,18	deleterious	3,5	23,1	0,43	0,55	disease	0,65	disease	0,68	disease	0,66	disease	0,54	1	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,19	medium_impact	0,51	0,63	0,8	13,27	13,52	N	0,24	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13740	13740	T	G	MI.22252	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1404	468	I	M	atT/atG	5,67	0,87	0	probably_damaging	1	neutral	0,29	neutral	0,77	neutral	-1,67	neutral	-1,81	medium_impact	2,12	neutral	0,82	neutral	0,77	deleterious	2,45	19,12	0,5	0,6	disease	0,78	disease	0,56	neutral	0,43	disease	0,54	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,02	medium_impact	0,73	0,8	0,85	13,27	13,52	N	0,46	N	0,75	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13740	13740	T	A	MI.22253	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1404	468	I	M	atT/atA	5,67	0,87	0	probably_damaging	1	neutral	0,29	neutral	0,77	neutral	-1,67	neutral	-1,81	medium_impact	2,12	neutral	0,82	neutral	0,77	deleterious	2,74	21	0,5	0,6	disease	0,78	disease	0,56	neutral	0,43	disease	0,54	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,02	medium_impact	0,73	0,8	0,85	13,27	13,52	N	0,47	N	0,75	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13741	13741	A	C	MI.22254	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1405	469	T	P	Act/Cct	-4,64	0	0	possibly_damaging	0,81	neutral	0,23	neutral	0,84	deleterious	-3,22	deleterious	-2,54	medium_impact	3,17	neutral	0,64	neutral	0,38	deleterious	3,53	23,1	0,16	0,45	disease	0,56	disease	0,84	disease	0,74	disease	0,8	6	neutral	0,87	neutral	0,21	NA	0	deleterious	0,76	low_impact	-1,34	medium_impact	-0,06	medium_impact	1,69	0,66	0,8	19,4	15,87	N	0,32	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13741	13741	A	G	MI.22255	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1405	469	T	A	Act/Gct	-4,64	0	0	benign	0,36	neutral	0,53	neutral	0,93	neutral	-0,83	neutral	-0,96	medium_impact	2,36	neutral	0,77	neutral	0,75	deleterious	2,02	16,33	0,61	0,65	neutral	0,42	neutral	0,44	disease	0,6	neutral	0,5	0	neutral	0,39	deleterious	0,59	neutral	-3	deleterious	0,49	medium_impact	-0,51	medium_impact	0,26	medium_impact	0,95	0,54	0,8	19,4	15,87	N	0,29	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13741	13741	A	T	MI.22256	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1405	469	T	S	Act/Tct	-4,64	0	0	benign	0,04	neutral	0,47	neutral	1,17	neutral	1,07	neutral	1,14	neutral_impact	0,59	neutral	0,82	neutral	0,96	neutral	1,11	11,25	0,44	0,55	neutral	0,29	neutral	0,21	neutral	0,33	neutral	0,36	3	neutral	0,49	deleterious	0,72	neutral	-6	deleterious	0,55	medium_impact	0,57	medium_impact	0,2	medium_impact	-0,66	0,63	0,8	19,4	15,87	N	0,33	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13742	13742	C	T	MI.22257	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1406	469	T	I	aCt/aTt	-0,06	0	0	benign	0,03	neutral	0,52	neutral	0,92	neutral	-0,94	deleterious	-2,94	low_impact	1,77	neutral	0,72	neutral	0,72	neutral	1,03	10,82	0,46	0,55	disease	0,8	disease	0,66	neutral	0,4	disease	0,59	2	neutral	0,45	deleterious	0,75	neutral	-6	neutral	0,24	medium_impact	0,69	medium_impact	0,25	medium_impact	0,41	0,67	0,85	19,4	15,87	N	0,28	N	0,89	polymorphism	1	0,06	rs386829191	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13742	13742	C	A	MI.22258	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1406	469	T	N	aCt/aAt	-0,06	0	0	possibly_damaging	0,69	neutral	0,32	neutral	0,89	neutral	-1,4	neutral	-1	medium_impact	2,19	neutral	0,81	neutral	0,74	deleterious	3,61	23,2	0,51	0,6	neutral	0,5	disease	0,72	disease	0,59	disease	0,66	3	neutral	0,75	neutral	0,32	NA	0	deleterious	0,7	low_impact	-1,08	medium_impact	0,05	medium_impact	0,8	0,7	0,85	19,4	15,87	N	0,28	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13742	13742	C	G	MI.22259	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1406	469	T	S	aCt/aGt	-0,06	0	0	benign	0,04	neutral	0,47	neutral	1,17	neutral	1,07	neutral	1,14	neutral_impact	0,59	neutral	0,82	neutral	0,96	neutral	1,27	12,14	0,44	0,55	neutral	0,29	neutral	0,21	neutral	0,33	neutral	0,36	3	neutral	0,49	deleterious	0,72	neutral	-6	deleterious	0,55	medium_impact	0,57	medium_impact	0,2	medium_impact	-0,66	0,63	0,8	19,4	15,87	N	0,34	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6069	6069	G	C	MI.2226	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	166	56	V	L	Gtt/Ctt	-3,34	0	0	benign	0,01	deleterious	0,04	neutral	2,9	neutral	-0,72	neutral	-1,41	medium_impact	3,48	damaging	0,56	damaging	0,15	deleterious	3,39	23	0,35	0,55	neutral	0,42	disease	0,85	neutral	0,3	disease	0,67	3	neutral	0,96	deleterious	0,52	deleterious	1	neutral	0,27	medium_impact	1,12	medium_impact	-0,58	high_impact	2,11	0,75	0,9	2,92	7,71	N	0,39	N	0,54	polymorphism	0,97	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13744	13744	A	T	MI.22260	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1408	470	N	Y	Aac/Tac	-3,5	0	0	benign	0,11	neutral	1	neutral	0,95	neutral	-1,01	deleterious	-3,85	low_impact	0,94	neutral	0,86	neutral	0,95	deleterious	1,85	15,26	0,38	0,5	disease	0,54	neutral	0,46	neutral	0,35	disease	0,54	1	neutral	0,11	deleterious	0,95	neutral	-6	deleterious	0,69	medium_impact	0,12	high_impact	1,89	medium_impact	-0,34	0,42	0,8	27,69	16,3	N	0,25	N	0,25	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13744	13744	A	C	MI.22261	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1408	470	N	H	Aac/Cac	-3,5	0	0	probably_damaging	0,91	neutral	0,54	neutral	0,93	neutral	-2,02	neutral	-2,22	neutral_impact	0,45	neutral	0,82	neutral	0,97	neutral	1,57	13,67	0,5	0,6	disease	0,71	neutral	0,34	neutral	0,44	disease	0,64	3	neutral	0,9	neutral	0,32	neutral	-2	deleterious	0,71	low_impact	-1,7	medium_impact	0,27	medium_impact	-0,79	0,47	0,8	27,69	16,3	N	0,28	N	0,1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13744	13744	A	G	MI.22262	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1408	470	N	D	Aac/Gac	-3,5	0	0	possibly_damaging	0,64	neutral	0,24	neutral	0,94	neutral	-1,3	deleterious	-3,18	medium_impact	2,21	neutral	0,78	neutral	0,47	neutral	1,31	12,3	0,63	0,65	disease	0,83	neutral	0,37	disease	0,53	disease	0,66	3	neutral	0,79	neutral	0,3	NA	0	deleterious	0,56	medium_impact	-0,98	medium_impact	-0,04	medium_impact	0,82	0,51	0,8	27,69	16,3	N	0,33	N	0,67	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13745	13745	A	C	MI.22263	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1409	470	N	T	aAc/aCc	-3,27	0	0	benign	0,13	neutral	0,44	neutral	0,97	neutral	-0,45	deleterious	-3,45	neutral_impact	0,28	neutral	0,84	neutral	0,82	deleterious	0,5	7,45	0,44	0,55	neutral	0,44	neutral	0,27	neutral	0,31	neutral	0,46	1	neutral	0,48	deleterious	0,66	neutral	-6	deleterious	0,44	medium_impact	0,04	medium_impact	0,18	medium_impact	-0,95	0,52	0,8	27,69	16,3	N	0,33	N	0,35	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13745	13745	A	T	MI.22264	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1409	470	N	I	aAc/aTc	-3,27	0	0	possibly_damaging	0,88	neutral	0,42	neutral	0,95	neutral	-0,93	deleterious	-5,14	low_impact	1,12	neutral	0,87	neutral	0,78	deleterious	2,64	20,4	0,33	0,5	neutral	0,35	disease	0,58	neutral	0,46	disease	0,51	0	neutral	0,87	neutral	0,27	neutral	-3	deleterious	0,64	low_impact	-1,57	medium_impact	0,16	medium_impact	-0,18	0,36	0,8	27,69	16,3	N	0,33	N	0,85	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13745	13745	A	G	MI.22265	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1409	470	N	S	aAc/aGc	-3,27	0	0	benign	0,09	neutral	0,46	neutral	1,06	neutral	0,72	deleterious	-2,59	neutral_impact	-0,56	neutral	0,83	neutral	0,91	neutral	-1,41	0	0,64	0,7	neutral	0,41	neutral	0,07	neutral	0,27	neutral	0,19	6	neutral	0,48	deleterious	0,69	neutral	-6	neutral	0,15	medium_impact	0,21	medium_impact	0,19	low_impact	-1,71	0,29	0,8	27,69	16,3	N	0,39	N	0,29	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13746	13746	C	G	MI.22266	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1410	470	N	K	aaC/aaG	-0,29	0	0	possibly_damaging	0,64	neutral	0,35	neutral	0,98	neutral	-0,42	deleterious	-3,51	low_impact	1,87	neutral	0,82	neutral	0,59	neutral	1,27	12,13	0,63	0,65	disease	0,72	neutral	0,47	disease	0,58	disease	0,63	3	neutral	0,7	neutral	0,36	neutral	-3	deleterious	0,62	medium_impact	-0,98	medium_impact	0,08	medium_impact	0,51	0,52	0,8	27,69	16,3	N	0,3	N	0,7	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13746	13746	C	A	MI.22267	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1410	470	N	K	aaC/aaA	-0,29	0	0	possibly_damaging	0,64	neutral	0,35	neutral	0,98	neutral	-0,42	deleterious	-3,51	low_impact	1,87	neutral	0,82	neutral	0,59	neutral	1,76	14,74	0,63	0,65	disease	0,72	neutral	0,47	disease	0,58	disease	0,63	3	neutral	0,7	neutral	0,36	neutral	-3	deleterious	0,62	medium_impact	-0,98	medium_impact	0,08	medium_impact	0,51	0,52	0,8	27,69	16,3	N	0,3	N	0,7	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13747	13747	A	C	MI.22268	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1411	471	N	H	Aac/Cac	-5,1	0	0	possibly_damaging	0,83	neutral	0,54	neutral	0,89	neutral	-2,52	deleterious	-3,27	low_impact	1,6	neutral	0,82	neutral	0,61	deleterious	2,98	22,2	0,4	0,5	disease	0,72	disease	0,71	disease	0,58	disease	0,64	3	neutral	0,81	neutral	0,36	neutral	-3	deleterious	0,74	low_impact	-1,4	medium_impact	0,27	medium_impact	0,26	0,56	0,8	10,78	14,57	N	0,2	N	0,54	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13747	13747	A	T	MI.22269	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1411	471	N	Y	Aac/Tac	-5,1	0	0	benign	0,04	neutral	1	neutral	0,94	neutral	-0,92	deleterious	-4,99	low_impact	1,17	neutral	0,83	neutral	0,73	deleterious	3,51	23,1	0,35	0,5	disease	0,53	disease	0,71	neutral	0,5	disease	0,54	1	neutral	0,04	deleterious	0,98	neutral	-6	deleterious	0,72	medium_impact	0,57	high_impact	1,89	medium_impact	-0,13	0,52	0,8	10,78	14,57	N	0,21	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6069	6069	G	A	MI.2227	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	166	56	V	I	Gtt/Att	-3,34	0	0	benign	0,17	deleterious	0,02	neutral	2,87	neutral	-0,04	neutral	-0,56	medium_impact	2,92	damaging	0,58	damaging	0,15	deleterious	3,56	23,1	0,41	0,55	disease	0,51	disease	0,77	neutral	0,42	disease	0,58	2	neutral	0,98	neutral	0,43	deleterious	1	neutral	0,28	medium_impact	-0,11	medium_impact	-0,75	medium_impact	1,6	0,72	0,9	2,92	7,71	N	0,36	N	0,13	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13747	13747	A	G	MI.22270	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1411	471	N	D	Aac/Gac	-5,1	0	0	possibly_damaging	0,48	neutral	0,23	neutral	0,88	deleterious	-3,18	deleterious	-3,16	medium_impact	2,92	neutral	0,71	neutral	0,49	deleterious	2,23	17,7	0,56	0,6	disease	0,73	disease	0,66	disease	0,74	disease	0,75	5	neutral	0,74	neutral	0,38	NA	0	deleterious	0,57	medium_impact	-0,71	medium_impact	-0,06	medium_impact	1,46	0,8	0,85	10,78	14,57	N	0,33	N	0,72	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13748	13748	A	T	MI.22271	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1412	471	N	I	aAc/aTc	1,77	0	0,01	possibly_damaging	0,75	neutral	0,41	neutral	0,99	neutral	-0,13	deleterious	-5,52	low_impact	1,72	neutral	0,82	neutral	0,73	deleterious	3,99	23,6	0,3	0,45	neutral	0,42	disease	0,82	disease	0,65	disease	0,57	1	neutral	0,76	neutral	0,33	neutral	-3	deleterious	0,69	low_impact	-1,2	medium_impact	0,15	medium_impact	0,37	0,42	0,8	10,78	14,57	N	0,26	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13748	13748	A	G	MI.22272	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1412	471	N	S	aAc/aGc	1,77	0	0,01	benign	0,04	neutral	0,46	neutral	0,97	neutral	-0,44	neutral	-2,13	neutral_impact	0,68	neutral	0,89	neutral	0,98	deleterious	0,13	3,91	0,52	0,6	disease	0,51	disease	0,53	neutral	0,47	neutral	0,49	0	neutral	0,5	deleterious	0,71	neutral	-6	neutral	0,21	medium_impact	0,57	medium_impact	0,19	medium_impact	-0,58	0,51	0,8	10,78	14,57	N	0,3	N	0,09	polymorphism	1	0,02	rs879029751	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13748	13748	A	C	MI.22273	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1412	471	N	T	aAc/aCc	1,77	0	0,01	benign	0,36	neutral	0,43	neutral	0,95	neutral	-0,65	deleterious	-3,1	low_impact	1,2	neutral	0,86	neutral	0,81	deleterious	1,89	15,52	0,39	0,5	disease	0,55	disease	0,59	neutral	0,45	neutral	0,5	0	neutral	0,5	deleterious	0,54	neutral	-6	deleterious	0,48	medium_impact	-0,51	medium_impact	0,17	medium_impact	-0,11	0,55	0,8	10,78	14,57	N	0,33	N	0,58	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13749	13749	C	G	MI.22274	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1413	471	N	K	aaC/aaG	-0,52	0	0	possibly_damaging	0,48	neutral	0,33	neutral	0,91	neutral	-1,74	deleterious	-3,66	medium_impact	2,92	neutral	0,73	neutral	0,56	deleterious	2,48	19,36	0,6	0,65	disease	0,72	disease	0,77	disease	0,76	disease	0,77	5	neutral	0,64	neutral	0,43	NA	0	deleterious	0,65	medium_impact	-0,71	medium_impact	0,06	medium_impact	1,46	0,7	0,85	10,78	14,57	N	0,34	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13749	13749	C	A	MI.22275	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1413	471	N	K	aaC/aaA	-0,52	0	0	possibly_damaging	0,48	neutral	0,33	neutral	0,91	neutral	-1,74	deleterious	-3,66	medium_impact	2,92	neutral	0,73	neutral	0,56	deleterious	3,01	22,3	0,6	0,65	disease	0,72	disease	0,77	disease	0,76	disease	0,77	5	neutral	0,64	neutral	0,43	NA	0	deleterious	0,65	medium_impact	-0,71	medium_impact	0,06	medium_impact	1,46	0,7	0,85	10,78	14,57	N	0,35	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13750	13750	A	T	MI.22276	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1414	472	I	F	Att/Ttt	-1,89	0	0	possibly_damaging	0,88	neutral	0,78	neutral	0,7	neutral	-2,25	deleterious	-2,97	medium_impact	2,08	neutral	0,76	neutral	0,83	deleterious	2,12	16,99	0,47	0,55	disease	0,54	disease	0,59	neutral	0,4	neutral	0,5	0	neutral	0,86	neutral	0,45	NA	0	deleterious	0,71	low_impact	-1,57	medium_impact	0,54	medium_impact	0,7	0,83	0,85	6,63	10,34	N	0,22	N	0,96	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13750	13750	A	C	MI.22277	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1414	472	I	L	Att/Ctt	-1,89	0	0	benign	0,05	neutral	0,97	neutral	0,91	neutral	-0,4	neutral	-0,96	low_impact	1,24	neutral	0,82	neutral	0,95	deleterious	2,28	18,06	0,42	0,55	neutral	0,34	neutral	0,32	neutral	0,32	neutral	0,47	1	neutral	0,01	deleterious	0,96	neutral	-6	deleterious	0,61	medium_impact	0,47	medium_impact	1,07	medium_impact	-0,07	0,79	0,85	6,63	10,34	N	0,27	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13750	13750	A	G	MI.22278	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1414	472	I	V	Att/Gtt	-1,89	0	0	benign	0,09	neutral	0,56	neutral	0,74	neutral	-1,64	neutral	-0,7	low_impact	1,84	neutral	0,89	neutral	0,79	deleterious	2,95	22	0,62	0,65	neutral	0,44	neutral	0,25	neutral	0,41	neutral	0,45	1	neutral	0,36	deleterious	0,74	neutral	-6	deleterious	0,62	medium_impact	0,21	medium_impact	0,29	medium_impact	0,48	0,68	0,85	6,63	10,34	N	0,32	N	0,74	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13751	13751	T	A	MI.22279	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1415	472	I	N	aTt/aAt	1,31	0,01	0	probably_damaging	0,95	neutral	0,48	neutral	0,64	deleterious	-3,79	deleterious	-5,37	medium_impact	2,48	neutral	0,8	neutral	0,41	deleterious	4,48	24,2	0,31	0,45	disease	0,87	disease	0,79	disease	0,59	disease	0,77	5	neutral	0,95	neutral	0,27	deleterious	1	deleterious	0,82	low_impact	-1,96	medium_impact	0,21	medium_impact	1,06	0,62	0,8	6,63	10,34	N	0,26	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6069	6069	G	T	MI.2228	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	166	56	V	F	Gtt/Ttt	-3,34	0	0	possibly_damaging	0,82	deleterious	0	neutral	2,82	neutral	-2,19	neutral	-2,46	high_impact	4,28	damaging	0,52	damaging	0,11	deleterious	3,73	23,3	0,15	0,55	disease	0,64	disease	0,95	disease	0,58	disease	0,8	6	deleterious	1	neutral	0,09	deleterious	5	deleterious	0,77	low_impact	-1,38	low_impact	-1,48	high_impact	2,85	0,6	0,9	2,92	7,71	N	0,36	N	0,85	polymorphism	0,73	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13751	13751	T	C	MI.22280	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1415	472	I	T	aTt/aCt	1,31	0,01	0	possibly_damaging	0,73	neutral	0,52	neutral	0,7	neutral	-2,17	deleterious	-3,53	low_impact	1,5	neutral	0,85	neutral	0,97	deleterious	2,33	18,37	0,44	0,55	disease	0,64	neutral	0,45	neutral	0,41	disease	0,61	2	neutral	0,7	neutral	0,4	neutral	-3	deleterious	0,74	low_impact	-1,16	medium_impact	0,25	medium_impact	0,17	0,7	0,85	6,63	10,34	N	0,35	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13751	13751	T	G	MI.22281	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1415	472	I	S	aTt/aGt	1,31	0,01	0	possibly_damaging	0,77	neutral	0,57	neutral	0,65	deleterious	-3,22	deleterious	-4,47	medium_impact	2,25	neutral	0,78	neutral	0,72	deleterious	4,33	24	0,26	0,45	disease	0,63	disease	0,74	disease	0,6	disease	0,58	2	neutral	0,73	neutral	0,4	NA	0	deleterious	0,77	low_impact	-1,24	medium_impact	0,3	medium_impact	0,85	0,64	0,8	6,63	10,34	N	0,24	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13752	13752	T	A	MI.22282	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1416	472	I	M	atT/atA	1,77	0,02	0	probably_damaging	0,91	neutral	0,33	neutral	0,71	neutral	-2,08	neutral	-1,6	low_impact	1,56	neutral	0,86	neutral	0,98	deleterious	2,62	20,3	0,54	0,6	disease	0,58	neutral	0,3	neutral	0,35	disease	0,6	2	neutral	0,92	neutral	0,21	neutral	-2	deleterious	0,68	low_impact	-1,7	medium_impact	0,06	medium_impact	0,22	0,87	0,9	6,63	10,34	N	0,41	N	0,76	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13752	13752	T	G	MI.22283	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1416	472	I	M	atT/atG	1,77	0,02	0	probably_damaging	0,91	neutral	0,33	neutral	0,71	neutral	-2,08	neutral	-1,6	low_impact	1,56	neutral	0,86	neutral	0,98	deleterious	2,41	18,89	0,54	0,6	disease	0,58	neutral	0,3	neutral	0,35	disease	0,6	2	neutral	0,92	neutral	0,21	neutral	-2	deleterious	0,68	low_impact	-1,7	medium_impact	0,06	medium_impact	0,22	0,87	0,9	6,63	10,34	N	0,41	N	0,76	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13753	13753	T	A	MI.22284	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1417	473	S	T	Tcc/Acc	-8,31	0	0	benign	0,02	neutral	0,48	neutral	1,01	neutral	0,25	neutral	0,51	neutral_impact	-0,96	neutral	0,85	neutral	0,99	deleterious	0,12	3,81	0,36	0,5	disease	0,6	neutral	0,08	neutral	0,23	neutral	0,31	4	neutral	0,5	deleterious	0,73	neutral	-6	neutral	0,25	medium_impact	0,86	medium_impact	0,21	low_impact	-2,08	0,68	0,85	15,09	12,43	N	0,41	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13753	13753	T	G	MI.22285	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1417	473	S	A	Tcc/Gcc	-8,31	0	0	benign	0,12	neutral	0,54	neutral	1,01	neutral	0,22	neutral	-0,33	low_impact	0,84	neutral	0,85	neutral	0,85	deleterious	0,14	4,03	0,43	0,55	disease	0,52	neutral	0,12	neutral	0,37	neutral	0,23	5	neutral	0,37	deleterious	0,71	neutral	-6	neutral	0,15	medium_impact	0,08	medium_impact	0,27	medium_impact	-0,44	0,58	0,8	15,09	12,43	N	0,32	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13753	13753	T	C	MI.22286	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1417	473	S	P	Tcc/Ccc	-8,31	0	0	benign	0,01	neutral	0,28	neutral	1,05	neutral	0,78	neutral	2,89	neutral_impact	-1,27	neutral	0,91	neutral	1	neutral	-0,15	1,38	0,25	0,45	neutral	0,39	neutral	0,36	neutral	0,21	neutral	0,46	1	neutral	0,72	deleterious	0,64	neutral	-6	neutral	0,16	medium_impact	1,15	medium_impact	0,01	low_impact	-2,36	0,48	0,8	15,09	12,43	N	0,31	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13754	13754	C	T	MI.22287	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1418	473	S	F	tCc/tTc	-5,33	0	0	benign	0,01	neutral	0,74	neutral	1,24	neutral	2,27	neutral	-2,13	neutral_impact	0,03	neutral	0,76	neutral	0,77	deleterious	0,56	7,87	0,26	0,45	disease	0,74	neutral	0,44	neutral	0,32	disease	0,63	3	neutral	0,23	deleterious	0,87	neutral	-6	neutral	0,36	medium_impact	1,15	medium_impact	0,48	low_impact	-1,18	0,4	0,8	15,09	12,43	N	0,25	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13754	13754	C	G	MI.22288	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1418	473	S	C	tCc/tGc	-5,33	0	0	possibly_damaging	0,89	neutral	0,17	neutral	0,95	neutral	-1,88	neutral	-1,28	low_impact	1,38	neutral	0,83	neutral	0,45	deleterious	2,31	18,25	0,28	0,45	disease	0,93	neutral	0,48	neutral	0,3	disease	0,7	4	neutral	0,94	neutral	0,14	neutral	-3	deleterious	0,68	low_impact	-1,61	medium_impact	-0,15	medium_impact	0,06	0,64	0,8	15,09	12,43	N	0,33	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13754	13754	C	A	MI.22289	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1418	473	S	Y	tCc/tAc	-5,33	0	0	benign	0,38	neutral	1	neutral	0,96	neutral	-1,05	neutral	-1,67	low_impact	1,04	neutral	0,86	neutral	0,84	neutral	1,31	12,31	0,25	0,45	disease	0,78	neutral	0,43	neutral	0,39	disease	0,64	3	neutral	0,38	deleterious	0,81	neutral	-6	deleterious	0,62	medium_impact	-0,54	high_impact	1,89	medium_impact	-0,25	0,6	0,8	15,09	12,43	N	0,21	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6070	6070	T	A	MI.2229	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	167	56	V	D	gTt/gAt	5,22	1	0	probably_damaging	0,96	deleterious	0,01	neutral	2,8	deleterious	-4,08	deleterious	-3,19	high_impact	4,62	damaging	0,55	damaging	0,12	deleterious	4,33	24	0,09	0,55	neutral	0,4	disease	0,94	disease	0,7	disease	0,82	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,82	low_impact	-2,06	medium_impact	-0,92	high_impact	3,17	0,51	0,9	2,92	7,71	P	0,51	P	0,92	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13756	13756	C	G	MI.22290	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1420	474	P	A	Ccc/Gcc	-8,54	0	0	probably_damaging	1	neutral	0,51	neutral	0,7	neutral	-2,27	deleterious	-6,69	high_impact	3,74	neutral	0,67	damaging	0,17	deleterious	3,26	22,8	0,38	0,5	disease	0,66	neutral	0,49	disease	0,68	disease	0,6	2	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,24	high_impact	2,21	0,74	0,85	5,31	7,81	N	0,27	N	0,73	polymorphism	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13756	13756	C	A	MI.22291	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1420	474	P	T	Ccc/Acc	-8,54	0	0	probably_damaging	1	neutral	0,47	neutral	0,68	neutral	-2,55	deleterious	-6,65	medium_impact	2,5	neutral	0,68	damaging	0,27	deleterious	3,84	23,4	0,36	0,5	disease	0,68	disease	0,73	disease	0,62	disease	0,62	2	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,2	medium_impact	1,08	0,7	0,85	5,31	7,81	N	0,22	N	0,91	polymorphism	0,98	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13756	13756	C	T	MI.22292	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1420	474	P	S	Ccc/Tcc	-8,54	0	0	probably_damaging	1	neutral	0,46	neutral	0,73	neutral	-1,8	deleterious	-6,69	medium_impact	3,05	neutral	0,67	damaging	0,12	deleterious	4,08	23,7	0,46	0,55	neutral	0,47	disease	0,73	disease	0,6	disease	0,62	2	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,19	medium_impact	1,58	0,28	0,8	5,31	7,81	N	0,16	N	0,78	polymorphism	0,98	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13757	13757	C	A	MI.22293	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1421	474	P	H	cCc/cAc	2	0,09	0	probably_damaging	1	neutral	0,52	neutral	0,63	deleterious	-4,1	deleterious	-7,27	high_impact	3,74	neutral	0,68	damaging	0,13	deleterious	4,17	23,8	0,32	0,5	disease	0,9	disease	0,79	disease	0,68	disease	0,78	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,25	high_impact	2,21	0,48	0,8	5,31	7,81	N	0,31	N	0,72	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13757	13757	C	T	MI.22294	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1421	474	P	L	cCc/cTc	2	0,09	0	probably_damaging	1	neutral	0,71	neutral	0,71	neutral	-2,03	deleterious	-8,2	medium_impact	3,05	neutral	0,65	damaging	0,24	deleterious	4,56	24,4	0,38	0,5	disease	0,62	disease	0,73	disease	0,6	disease	0,53	1	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,45	medium_impact	1,58	0,77	0,85	5,31	7,81	N	0,28	N	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13757	13757	C	G	MI.22295	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1421	474	P	R	cCc/cGc	2	0,09	0	probably_damaging	1	neutral	0,35	neutral	0,66	deleterious	-3,08	deleterious	-7,53	high_impact	3,74	neutral	0,63	damaging	0,13	deleterious	3,78	23,4	0,35	0,5	disease	0,8	disease	0,84	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,08	high_impact	2,21	0,57	0,8	5,31	7,81	N	0,43	N	0,64	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13759	13759	G	T	MI.22296	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1423	475	A	S	Gca/Tca	-11,52	0	0,09	benign	0,18	neutral	0,44	neutral	3,79	neutral	-0,61	neutral	0,34	neutral_impact	-0,84	neutral	0,84	neutral	0,82	deleterious	0,52	7,55	0,42	0,5	disease	0,62	neutral	0,14	neutral	0,23	neutral	0,31	4	neutral	0,47	deleterious	0,63	neutral	-6	neutral	0,17	medium_impact	-0,12	medium_impact	0,18	low_impact	-1,97	0,69	0,85	11,94	9,67	N	0,4	N	0,08	polymorphism	1	0	rs386420024	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13759	13759	G	C	MI.22297	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1423	475	A	P	Gca/Cca	-11,52	0	0,09	possibly_damaging	0,62	neutral	0,26	neutral	3,68	neutral	-2,41	neutral	-1,1	neutral_impact	-0,31	neutral	0,78	neutral	0,68	deleterious	2,12	17,01	0,23	0,45	disease	0,85	disease	0,58	neutral	0,28	disease	0,64	3	neutral	0,76	neutral	0,32	neutral	-3	neutral	0,34	medium_impact	-0,95	medium_impact	-0,02	low_impact	-1,49	0,68	0,85	11,94	9,67	N	0,33	N	0,22	polymorphism	1	0,02	rs386420024	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13759	13759	G	A	MI.22298	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1423	475	A	T	Gca/Aca	-11,52	0	0,09	benign	0,01	neutral	0,47	neutral	3,76	neutral	-0,91	neutral	1,66	neutral_impact	-2,07	neutral	0,94	neutral	0,96	neutral	-0,29	0,69	0,44	0,55	neutral	0,39	neutral	0,06	neutral	0,21	neutral	0,25	5	neutral	0,52	deleterious	0,73	neutral	-6	neutral	0,08	medium_impact	1,15	medium_impact	0,2	low_impact	-3,09	0,72	0,85	11,94	9,67	N	0,44	N	0,07	polymorphism	1	0	rs386420024	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13760	13760	C	A	MI.22299	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1424	475	A	E	gCa/gAa	-1,67	0	0	benign	0,34	neutral	0,27	neutral	3,73	neutral	-1,08	neutral	-1	neutral_impact	0,17	neutral	0,85	neutral	0,71	neutral	1,68	14,3	0,26	0,45	disease	0,71	neutral	0,47	disease	0,51	disease	0,63	3	neutral	0,68	neutral	0,47	neutral	-6	neutral	0,25	medium_impact	-0,47	medium_impact	-0,01	low_impact	-1,05	0,7	0,85	11,94	9,67	N	0,36	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8631	8631	A	C	MI.223	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	105	35	K	N	aaA/aaC	-0,8	0	0	benign	0,01	neutral	0,43	neutral	4,35	neutral	-1,03	neutral	0,49	neutral_impact	-0,7	neutral	0,88	neutral	0,95	neutral	-1,08	0,01	0,65	0,7	neutral	0,34	neutral	0,14	neutral	0,25	neutral	0,22	6	neutral	0,56	deleterious	0,71	neutral	-6	neutral	0,14	medium_impact	1,14	medium_impact	0,22	low_impact	-1,7	0,6	0,9	20,35	18,29	N	0,44	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6070	6070	T	G	MI.2230	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	167	56	V	G	gTt/gGt	5,22	1	0	probably_damaging	0,95	deleterious	0,04	neutral	2,81	deleterious	-3,55	deleterious	-3,34	medium_impact	3,38	damaging	0,55	damaging	0,15	deleterious	3,69	23,3	0,13	0,55	neutral	0,3	disease	0,9	disease	0,6	disease	0,75	5	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,76	low_impact	-1,96	medium_impact	-0,58	high_impact	2,02	0,51	0,9	2,92	7,71	N	0,42	N	0,74	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13760	13760	C	T	MI.22300	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1424	475	A	V	gCa/gTa	-1,67	0	0	benign	0,12	neutral	0,5	neutral	3,77	neutral	-0,59	neutral	0,49	neutral_impact	0,42	neutral	0,86	neutral	0,77	neutral	1,5	13,3	0,36	0,5	neutral	0,44	neutral	0,22	neutral	0,38	neutral	0,39	2	neutral	0,42	deleterious	0,69	neutral	-6	neutral	0,13	medium_impact	0,08	medium_impact	0,23	medium_impact	-0,82	0,69	0,85	11,94	9,67	N	0,35	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13760	13760	C	G	MI.22301	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1424	475	A	G	gCa/gGa	-1,67	0	0	benign	0,24	neutral	0,35	neutral	3,72	neutral	-1,11	neutral	-1,77	low_impact	0,98	neutral	0,84	neutral	0,64	neutral	1,11	11,29	0,32	0,5	disease	0,8	neutral	0,2	neutral	0,38	neutral	0,49	0	neutral	0,58	deleterious	0,56	neutral	-6	neutral	0,19	medium_impact	-0,27	medium_impact	0,08	medium_impact	-0,31	0,65	0,8	11,94	9,67	N	0,37	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13762	13762	T	A	MI.22302	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1426	476	S	T	Tcc/Acc	-5,79	0	0,02	benign	0,03	neutral	0,47	neutral	1,04	neutral	0,54	neutral	0,29	neutral_impact	-0,04	neutral	0,89	neutral	0,99	neutral	1,28	12,17	0,39	0,5	neutral	0,36	neutral	0,12	neutral	0,3	neutral	0,31	4	neutral	0,5	deleterious	0,72	neutral	-6	deleterious	0,48	medium_impact	0,69	medium_impact	0,2	low_impact	-1,24	0,53	0,8	17,08	12,86	N	0,47	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13762	13762	T	G	MI.22303	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1426	476	S	A	Tcc/Gcc	-5,79	0	0,02	benign	0,27	neutral	0,58	neutral	1,01	neutral	0,19	neutral	-1,91	medium_impact	1,96	neutral	0,82	neutral	0,8	neutral	1,22	11,86	0,55	0,6	neutral	0,49	neutral	0,18	disease	0,53	neutral	0,3	4	neutral	0,31	deleterious	0,66	neutral	-3	neutral	0,38	medium_impact	-0,34	medium_impact	0,31	medium_impact	0,59	0,54	0,8	17,08	12,86	N	0,32	N	0,18	polymorphism	1	0,02	rs879154715	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13762	13762	T	C	MI.22304	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1426	476	S	P	Tcc/Ccc	-5,79	0	0,02	possibly_damaging	0,73	neutral	0,24	neutral	0,95	neutral	-0,98	deleterious	-2,69	low_impact	1,75	neutral	0,61	neutral	0,62	deleterious	4,07	23,7	0,34	0,5	disease	0,73	disease	0,73	disease	0,52	disease	0,62	2	neutral	0,83	neutral	0,26	neutral	-3	deleterious	0,79	low_impact	-1,16	medium_impact	-0,04	medium_impact	0,4	0,46	0,8	17,08	12,86	N	0,29	N	0,69	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13763	13763	C	T	MI.22305	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1427	476	S	F	tCc/tTc	2	0	0	benign	0,03	neutral	0,72	neutral	0,93	neutral	-1,83	deleterious	-3,6	medium_impact	1,96	neutral	0,73	neutral	0,71	neutral	1,31	12,32	0,28	0,45	disease	0,88	disease	0,61	disease	0,61	disease	0,76	5	neutral	0,23	deleterious	0,85	neutral	-3	neutral	0,29	medium_impact	0,69	medium_impact	0,46	medium_impact	0,59	0,4	0,8	17,08	12,86	N	0,23	N	0,72	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13763	13763	C	G	MI.22306	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1427	476	S	C	tCc/tGc	2	0	0	probably_damaging	0,93	neutral	0,18	neutral	0,91	deleterious	-3,59	deleterious	-3	medium_impact	2,31	neutral	0,62	neutral	0,44	deleterious	3,65	23,2	0,38	0,5	disease	0,93	disease	0,53	disease	0,56	disease	0,8	6	neutral	0,96	neutral	0,13	deleterious	1	deleterious	0,77	low_impact	-1,81	medium_impact	-0,13	medium_impact	0,91	0,59	0,8	17,08	12,86	N	0,33	N	0,54	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13763	13763	C	A	MI.22307	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1427	476	S	Y	tCc/tAc	2	0	0	possibly_damaging	0,51	neutral	1	neutral	0,97	neutral	-0,6	deleterious	-3,33	low_impact	0,95	neutral	0,82	neutral	0,68	deleterious	2,71	20,9	0,3	0,45	disease	0,61	neutral	0,5	disease	0,54	disease	0,63	3	neutral	0,51	deleterious	0,75	neutral	-3	deleterious	0,53	medium_impact	-0,76	high_impact	1,89	medium_impact	-0,34	0,57	0,8	17,08	12,86	N	0,23	N	0,73	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13765	13765	C	A	MI.22308	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1429	477	P	T	Ccc/Acc	-3,27	0	0	benign	0	neutral	0,5	neutral	0,98	neutral	-0,15	neutral	2,48	neutral_impact	-0,38	neutral	0,81	neutral	0,97	neutral	-0,8	0,04	0,43	0,55	disease	0,63	neutral	0,07	neutral	0,21	neutral	0,33	4	neutral	0,5	deleterious	0,75	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,23	low_impact	-1,55	0,68	0,85	28,19	19,7	N	0,35	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13765	13765	C	T	MI.22309	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1429	477	P	S	Ccc/Tcc	-3,27	0	0	benign	0,11	neutral	0,54	neutral	0,9	neutral	-0,82	neutral	0,96	low_impact	0,92	neutral	0,87	neutral	0,87	neutral	1,07	11,05	0,48	0,55	disease	0,55	neutral	0,29	neutral	0,34	disease	0,57	1	neutral	0,37	deleterious	0,72	neutral	-6	neutral	0,2	medium_impact	0,12	medium_impact	0,27	medium_impact	-0,36	0,27	0,8	28,19	19,7	N	0,29	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6070	6070	T	C	MI.2231	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	167	56	V	A	gTt/gCt	5,22	1	0	possibly_damaging	0,7	deleterious	0,02	neutral	2,89	neutral	-1,84	neutral	-1,64	medium_impact	2,81	damaging	0,57	damaging	0,16	deleterious	3,39	23	0,26	0,55	neutral	0,3	disease	0,74	neutral	0,36	disease	0,53	1	deleterious	0,98	neutral	0,16	deleterious	4	deleterious	0,48	low_impact	-1,1	medium_impact	-0,75	medium_impact	1,5	0,58	0,9	2,92	7,71	P	0,53	P	0,1	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13765	13765	C	G	MI.22310	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1429	477	P	A	Ccc/Gcc	-3,27	0	0	benign	0,05	neutral	0,63	neutral	0,86	neutral	-1,43	neutral	1,07	medium_impact	1,97	neutral	0,84	neutral	0,79	neutral	1,27	12,12	0,42	0,55	disease	0,62	neutral	0,16	disease	0,59	neutral	0,37	3	neutral	0,3	deleterious	0,79	neutral	-3	neutral	0,16	medium_impact	0,47	medium_impact	0,36	medium_impact	0,6	0,72	0,85	28,19	19,7	N	0,3	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13766	13766	C	T	MI.22311	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1430	477	P	L	cCc/cTc	-0,98	0	0	benign	0	neutral	0,72	neutral	0,85	neutral	-1,53	neutral	2,01	neutral_impact	0,72	neutral	0,87	neutral	0,84	neutral	1,43	12,95	0,45	0,55	disease	0,78	neutral	0,4	disease	0,57	disease	0,68	4	neutral	0,27	deleterious	0,86	neutral	-6	neutral	0,2	high_impact	2,1	medium_impact	0,46	medium_impact	-0,55	0,79	0,85	28,19	19,7	N	0,28	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13766	13766	C	G	MI.22312	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1430	477	P	R	cCc/cGc	-0,98	0	0	benign	0,11	neutral	0,44	neutral	0,81	neutral	-2,41	neutral	-0,13	medium_impact	2,31	neutral	0,76	neutral	0,47	deleterious	1,99	16,13	0,36	0,5	disease	0,64	disease	0,58	disease	0,68	disease	0,72	4	neutral	0,49	deleterious	0,67	neutral	-3	neutral	0,38	medium_impact	0,12	medium_impact	0,18	medium_impact	0,91	0,65	0,8	28,19	19,7	N	0,31	N	0,16	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13766	13766	C	A	MI.22313	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1430	477	P	H	cCc/cAc	-0,98	0	0	benign	0,01	neutral	0,56	neutral	0,8	neutral	-2,73	neutral	-0,43	medium_impact	2,31	neutral	0,83	neutral	0,66	deleterious	3,88	23,5	0,41	0,5	disease	0,8	neutral	0,39	disease	0,66	disease	0,69	4	neutral	0,42	deleterious	0,78	neutral	-3	deleterious	0,64	medium_impact	1,15	medium_impact	0,29	medium_impact	0,91	0,59	0,8	28,19	19,7	N	0,29	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13768	13768	T	C	MI.22314	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1432	478	F	L	Ttc/Ctc	-11,98	0	0,01	benign	0	neutral	0,67	neutral	1,07	neutral	1,7	neutral	0,58	neutral_impact	-1,15	neutral	0,85	neutral	0,84	deleterious	2,27	17,98	0,46	0,55	disease	0,57	neutral	0,25	neutral	0,42	disease	0,54	1	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,16	high_impact	2,1	medium_impact	0,4	low_impact	-2,25	0,48	0,8	25,7	17,51	N	0,35	N	0,26	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13768	13768	T	A	MI.22315	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1432	478	F	I	Ttc/Atc	-11,98	0	0,01	benign	0,01	neutral	0,42	neutral	1,06	neutral	1,5	neutral	0,5	neutral_impact	-2,14	neutral	0,81	neutral	0,95	neutral	1,49	13,24	0,25	0,45	disease	0,74	neutral	0,21	neutral	0,31	neutral	0,5	0	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,19	medium_impact	1,15	medium_impact	0,16	low_impact	-3,16	0,49	0,8	25,7	17,51	N	0,36	N	0,26	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13768	13768	T	G	MI.22316	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1432	478	F	V	Ttc/Gtc	-11,98	0	0,01	benign	0	neutral	0,51	neutral	1,07	neutral	1,73	neutral	1,23	neutral_impact	-1,04	neutral	0,79	neutral	0,88	deleterious	2,3	18,19	0,37	0,5	disease	0,68	neutral	0,36	disease	0,55	disease	0,64	3	neutral	0,49	deleterious	0,76	neutral	-6	neutral	0,19	high_impact	2,1	medium_impact	0,24	low_impact	-2,15	0,43	0,8	25,7	17,51	N	0,35	N	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13769	13769	T	G	MI.22317	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1433	478	F	C	tTc/tGc	1,54	0	0	benign	0,02	neutral	0,17	neutral	1,01	neutral	0,3	neutral	0,34	neutral_impact	0	neutral	0,7	neutral	0,45	deleterious	2,34	18,41	0,26	0,45	disease	0,9	disease	0,53	disease	0,57	disease	0,76	5	neutral	0,82	deleterious	0,58	neutral	-6	neutral	0,26	medium_impact	0,86	medium_impact	-0,15	low_impact	-1,2	0,3	0,8	25,7	17,51	N	0,38	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13769	13769	T	A	MI.22318	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1433	478	F	Y	tTc/tAc	1,54	0	0	benign	0,01	neutral	1	neutral	1,1	neutral	2,07	neutral	0,88	neutral_impact	0	neutral	0,82	neutral	0,65	deleterious	2,44	19,07	0,38	0,5	disease	0,58	neutral	0,27	disease	0,53	disease	0,57	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,19	medium_impact	1,15	high_impact	1,89	low_impact	-1,2	0,5	0,8	25,7	17,51	N	0,3	N	0,15	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13769	13769	T	C	MI.22319	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1433	478	F	S	tTc/tCc	1,54	0	0	benign	0	neutral	0,41	neutral	1,1	neutral	2,1	neutral	2,12	neutral_impact	-1,32	neutral	0,82	neutral	0,9	deleterious	2,43	19	0,39	0,5	neutral	0,49	neutral	0,36	neutral	0,37	neutral	0,42	2	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,18	high_impact	2,1	medium_impact	0,15	low_impact	-2,41	0,42	0,8	25,7	17,51	N	0,34	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6072	6072	A	G	MI.2232	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	169	57	I	V	Atc/Gtc	-9,82	0	0	benign	0,01	neutral	0,42	neutral	2,79	neutral	-0,21	neutral	-0,46	low_impact	1,34	neutral	0,72	neutral	0,94	neutral	-0,27	0,77	0,51	0,6	neutral	0,2	neutral	0,36	neutral	0,35	neutral	0,43	2	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,14	medium_impact	1,12	medium_impact	0,12	medium_impact	0,14	0,66	0,9	5,26	53,05	N	0,47	N	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13770	13770	C	G	MI.22320	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1434	478	F	L	ttC/ttG	0,86	0	0	benign	0	neutral	0,67	neutral	1,07	neutral	1,7	neutral	0,58	neutral_impact	-1,15	neutral	0,85	neutral	0,84	deleterious	2,57	19,91	0,46	0,55	disease	0,57	neutral	0,25	neutral	0,42	disease	0,54	1	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,16	high_impact	2,1	medium_impact	0,4	low_impact	-2,25	0,48	0,8	25,7	17,51	N	0,36	N	0,26	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13770	13770	C	A	MI.22321	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1434	478	F	L	ttC/ttA	0,86	0	0	benign	0	neutral	0,67	neutral	1,07	neutral	1,7	neutral	0,58	neutral_impact	-1,15	neutral	0,85	neutral	0,84	deleterious	2,85	21,6	0,46	0,55	disease	0,57	neutral	0,25	neutral	0,42	disease	0,54	1	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,16	high_impact	2,1	medium_impact	0,4	low_impact	-2,25	0,48	0,8	25,7	17,51	N	0,36	N	0,26	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13771	13771	C	A	MI.22322	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1435	479	Q	K	Caa/Aaa	-10,37	0	0	possibly_damaging	0,89	neutral	0,98	neutral	0,98	neutral	-0,83	deleterious	-2,61	medium_impact	2,19	neutral	0,82	neutral	0,54	neutral	1,48	13,19	0,54	0,6	disease	0,57	neutral	0,46	disease	0,6	disease	0,64	3	neutral	0,89	deleterious	0,55	NA	0	deleterious	0,74	low_impact	-1,61	medium_impact	1,17	medium_impact	0,8	0,54	0,8	28,69	18,45	N	0,2	N	0,56	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13771	13771	C	G	MI.22323	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1435	479	Q	E	Caa/Gaa	-10,37	0	0	possibly_damaging	0,84	neutral	0,97	neutral	0,99	neutral	-0,4	neutral	-1,94	low_impact	1,5	neutral	0,85	neutral	0,9	deleterious	0,56	7,87	0,57	0,65	neutral	0,4	neutral	0,38	disease	0,58	neutral	0,49	0	neutral	0,83	deleterious	0,57	neutral	-3	deleterious	0,69	low_impact	-1,43	medium_impact	1,07	medium_impact	0,17	0,59	0,8	28,69	18,45	N	0,29	N	0,5	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13772	13772	A	C	MI.22324	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1436	479	Q	P	cAa/cCa	-0,52	0	0	benign	0,12	neutral	0,44	neutral	1,03	neutral	0,54	deleterious	-3,63	neutral_impact	-0,61	neutral	0,85	neutral	0,92	deleterious	1,98	16,06	0,25	0,45	disease	0,76	neutral	0,45	neutral	0,35	disease	0,65	3	neutral	0,49	deleterious	0,66	neutral	-6	deleterious	0,79	medium_impact	0,08	medium_impact	0,18	low_impact	-1,76	0,45	0,8	28,69	18,45	N	0,26	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13772	13772	A	G	MI.22325	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1436	479	Q	R	cAa/cGa	-0,52	0	0	probably_damaging	0,95	neutral	0,68	neutral	0,97	neutral	-1,01	deleterious	-2,68	medium_impact	2,19	neutral	0,82	neutral	0,48	neutral	1,62	13,97	0,62	0,65	disease	0,63	neutral	0,47	disease	0,63	disease	0,66	3	neutral	0,94	neutral	0,37	deleterious	1	deleterious	0,77	low_impact	-1,96	medium_impact	0,41	medium_impact	0,8	0,43	0,8	28,69	18,45	N	0,21	N	0,49	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13772	13772	A	T	MI.22326	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1436	479	Q	L	cAa/cTa	-0,52	0	0	probably_damaging	0,94	neutral	0,9	neutral	1,14	neutral	1,85	deleterious	-4,23	low_impact	0,91	neutral	0,84	neutral	0,92	deleterious	2,21	17,6	0,34	0,5	neutral	0,26	neutral	0,44	neutral	0,36	neutral	0,46	1	neutral	0,93	deleterious	0,48	neutral	-2	deleterious	0,66	low_impact	-1,88	medium_impact	0,76	medium_impact	-0,37	0,15	0,8	28,69	18,45	N	0,26	N	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13773	13773	A	T	MI.22327	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1437	479	Q	H	caA/caT	-0,29	0	0	probably_damaging	0,99	neutral	0,55	neutral	0,96	neutral	-1,64	deleterious	-3,25	medium_impact	2,19	neutral	0,81	neutral	0,64	deleterious	2,28	18,01	0,65	0,7	disease	0,74	neutral	0,31	neutral	0,45	disease	0,64	3	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,74	low_impact	-2,64	medium_impact	0,28	medium_impact	0,8	0,59	0,8	28,69	18,45	N	0,27	N	0,57	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13773	13773	A	C	MI.22328	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1437	479	Q	H	caA/caC	-0,29	0	0	probably_damaging	0,99	neutral	0,55	neutral	0,96	neutral	-1,64	deleterious	-3,25	medium_impact	2,19	neutral	0,81	neutral	0,64	deleterious	2,05	16,55	0,65	0,7	disease	0,74	neutral	0,31	neutral	0,45	disease	0,64	3	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,74	low_impact	-2,64	medium_impact	0,28	medium_impact	0,8	0,59	0,8	28,69	18,45	N	0,27	N	0,57	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13774	13774	A	C	MI.22329	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1438	480	T	P	Aca/Cca	-2,58	0	0	benign	0	neutral	0,27	neutral	0,96	neutral	-0,76	neutral	-1,39	low_impact	1,44	neutral	0,79	neutral	0,63	deleterious	3,43	23	0,23	0,45	disease	0,81	disease	0,73	disease	0,58	disease	0,7	4	neutral	0,73	deleterious	0,64	neutral	-6	deleterious	0,76	high_impact	2,1	medium_impact	-0,01	medium_impact	0,11	0,64	0,8	23,38	16,6	N	0,26	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6072	6072	A	C	MI.2233	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	169	57	I	L	Atc/Ctc	-9,82	0	0	benign	0,07	neutral	0,14	neutral	2,83	neutral	0,87	neutral	-0,93	low_impact	1,25	neutral	0,66	neutral	0,88	deleterious	0,64	8,45	0,3	0,55	neutral	0,22	disease	0,58	neutral	0,31	neutral	0,44	1	neutral	0,85	deleterious	0,54	neutral	-6	neutral	0,2	medium_impact	0,3	medium_impact	-0,25	medium_impact	0,06	0,71	0,9	5,26	53,05	N	0,52	P	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13774	13774	A	G	MI.22330	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1438	480	T	A	Aca/Gca	-2,58	0	0	benign	0,05	neutral	0,54	neutral	0,98	neutral	-0,31	neutral	-0,32	medium_impact	2,24	neutral	0,8	neutral	0,81	neutral	1,75	14,69	0,63	0,65	neutral	0,45	neutral	0,24	disease	0,6	neutral	0,47	1	neutral	0,4	deleterious	0,75	neutral	-3	neutral	0,29	medium_impact	0,47	medium_impact	0,27	medium_impact	0,84	0,37	0,8	23,38	16,6	N	0,31	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13774	13774	A	T	MI.22331	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1438	480	T	S	Aca/Tca	-2,58	0	0	benign	0,01	neutral	0,45	neutral	0,98	neutral	-0,35	neutral	-0,45	medium_impact	2,24	neutral	0,77	neutral	0,71	neutral	1,65	14,12	0,51	0,6	disease	0,61	neutral	0,34	disease	0,56	disease	0,63	3	neutral	0,54	deleterious	0,72	neutral	-3	neutral	0,41	medium_impact	1,15	medium_impact	0,18	medium_impact	0,84	0,7	0,85	23,38	16,6	N	0,34	N	0,12	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13775	13775	C	A	MI.22332	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1439	480	T	K	aCa/aAa	0,86	0	0	benign	0,11	neutral	0,35	neutral	0,93	neutral	-1,79	neutral	-0,59	low_impact	1,9	neutral	0,72	neutral	0,61	deleterious	3	22,2	0,33	0,5	disease	0,58	disease	0,6	disease	0,71	disease	0,74	5	neutral	0,6	deleterious	0,62	neutral	-6	deleterious	0,52	medium_impact	0,12	medium_impact	0,08	medium_impact	0,53	0,59	0,8	23,38	16,6	N	0,35	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13775	13775	C	T	MI.22333	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1439	480	T	M	aCa/aTa	0,86	0	0	benign	0,02	neutral	0,25	neutral	1,12	neutral	1,17	neutral	4,05	neutral_impact	-0,88	neutral	0,83	neutral	0,99	neutral	-0,5	0,22	0,45	0,55	neutral	0,45	neutral	0,05	neutral	0,17	neutral	0,25	5	neutral	0,74	deleterious	0,62	neutral	-6	neutral	0,14	medium_impact	0,86	medium_impact	-0,03	low_impact	-2,01	0,77	0,85	23,38	16,6	N	0,5	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13777	13777	A	T	MI.22334	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1441	481	T	S	Aca/Tca	-0,06	0	0	possibly_damaging	0,81	neutral	0,54	neutral	0,74	neutral	-2,49	deleterious	-3,58	medium_impact	2,64	neutral	0,71	neutral	0,66	deleterious	2,45	19,14	0,57	0,65	disease	0,63	neutral	0,38	neutral	0,44	disease	0,59	2	neutral	0,79	neutral	0,37	NA	0	deleterious	0,75	low_impact	-1,34	medium_impact	0,27	medium_impact	1,21	0,77	0,85	11,11	6,9	N	0,31	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13777	13777	A	C	MI.22335	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1441	481	T	P	Aca/Cca	-0,06	0	0	probably_damaging	0,98	neutral	0,33	neutral	0,7	deleterious	-3,52	deleterious	-5,33	high_impact	3,88	neutral	0,67	neutral	0,48	deleterious	3,64	23,2	0,21	0,45	disease	0,88	disease	0,79	disease	0,7	disease	0,78	6	deleterious	0,98	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-2,35	medium_impact	0,06	high_impact	2,34	0,51	0,8	11,11	6,9	N	0,35	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13777	13777	A	G	MI.22336	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1441	481	T	A	Aca/Gca	-0,06	0	0	benign	0,17	neutral	0,57	neutral	0,75	neutral	-2,17	deleterious	-4,46	high_impact	3,88	neutral	0,81	neutral	0,54	deleterious	3,63	23,2	0,66	0,7	disease	0,67	neutral	0,43	disease	0,7	disease	0,66	3	neutral	0,32	deleterious	0,7	neutral	-2	deleterious	0,76	medium_impact	-0,09	medium_impact	0,3	high_impact	2,34	0,35	0,8	11,11	6,9	N	0,35	N	0,69	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13778	13778	C	A	MI.22337	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1442	481	T	K	aCa/aAa	6,13	1	0	probably_damaging	0,91	neutral	0,44	neutral	0,7	deleterious	-3,46	deleterious	-5,33	high_impact	3,88	neutral	0,75	neutral	0,4	deleterious	4,65	24,5	0,29	0,45	disease	0,73	disease	0,78	disease	0,8	disease	0,8	6	neutral	0,91	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-1,7	medium_impact	0,18	high_impact	2,34	0,62	0,8	11,11	6,9	P	0,65	P	1	disease_causing	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13778	13778	C	T	MI.22338	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1442	481	T	M	aCa/aTa	6,13	1	0	possibly_damaging	0,61	neutral	0,52	neutral	0,74	neutral	-2,38	deleterious	-4,74	high_impact	3,54	neutral	0,76	neutral	0,58	deleterious	4,09	23,7	0,43	0,55	neutral	0,41	disease	0,61	disease	0,74	disease	0,61	2	neutral	0,58	neutral	0,46	deleterious	1	deleterious	0,72	medium_impact	-0,93	medium_impact	0,25	high_impact	2,03	0,75	0,85	11,11	6,9	P	0,57	P	0,93	disease_causing	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13780	13780	A	T	MI.22339	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1444	482	I	F	Atc/Ttc	-14,73	0	0,05	benign	0,26	neutral	0,71	neutral	0,95	neutral	-0,75	neutral	-0,99	neutral_impact	0,49	neutral	0,71	neutral	0,63	deleterious	2,36	18,58	0,58	0,65	disease	0,76	disease	0,61	disease	0,62	disease	0,7	4	neutral	0,2	deleterious	0,73	neutral	-6	deleterious	0,55	medium_impact	-0,32	medium_impact	0,45	medium_impact	-0,76	0,63	0,8	8,13	10,88	N	0,24	N	0,31	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6072	6072	A	T	MI.2234	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	169	57	I	F	Atc/Ttc	-9,82	0	0	possibly_damaging	0,55	deleterious	0,02	neutral	2,65	neutral	-0,96	neutral	-2,28	medium_impact	3,03	damaging	0,57	damaging	0,1	deleterious	3,27	22,8	0,26	0,55	disease	0,54	disease	0,83	neutral	0,4	disease	0,55	1	neutral	0,98	neutral	0,24	deleterious	4	deleterious	0,65	medium_impact	-0,84	medium_impact	-0,75	medium_impact	1,7	0,76	0,9	5,26	53,05	N	0,26	N	0,84	polymorphism	0,87	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13780	13780	A	G	MI.22340	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1444	482	I	V	Atc/Gtc	-14,73	0	0,05	benign	0,01	neutral	0,51	neutral	1,06	neutral	0,54	neutral	-0,03	neutral_impact	0,69	neutral	0,8	neutral	0,64	neutral	1,28	12,18	0,62	0,65	disease	0,56	neutral	0,23	disease	0,57	disease	0,54	1	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,24	medium_impact	-0,57	0,46	0,8	8,13	10,88	N	0,27	N	0,18	polymorphism	1	0,01	rs41358152	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13780	13780	A	C	MI.22341	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1444	482	I	L	Atc/Ctc	-14,73	0	0,05	benign	0,02	neutral	0,67	neutral	1,25	neutral	1,62	neutral	0,81	neutral_impact	-0,35	neutral	0,73	neutral	0,77	deleterious	2,04	16,44	0,47	0,55	disease	0,54	neutral	0,31	neutral	0,47	neutral	0,5	0	neutral	0,3	deleterious	0,83	neutral	-6	neutral	0,2	medium_impact	0,86	medium_impact	0,4	low_impact	-1,52	0,55	0,8	8,13	10,88	N	0,36	N	0,25	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13781	13781	T	G	MI.22342	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1445	482	I	S	aTc/aGc	8,42	1	0	benign	0,18	neutral	0,42	neutral	0,92	neutral	-1,33	neutral	-1,91	low_impact	1,04	neutral	0,71	neutral	0,67	deleterious	2,61	20,3	0,4	0,5	disease	0,7	disease	0,62	disease	0,62	disease	0,7	4	neutral	0,5	deleterious	0,62	neutral	-6	neutral	0,4	medium_impact	-0,12	medium_impact	0,16	medium_impact	-0,25	0,59	0,8	8,13	10,88	P	0,53	P	0,28	polymorphism	0,8	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13781	13781	T	C	MI.22343	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1445	482	I	T	aTc/aCc	8,42	1	0	benign	0,02	neutral	0,41	neutral	0,94	neutral	-0,85	neutral	-1,88	low_impact	1,04	neutral	0,78	neutral	0,72	neutral	1,63	14,04	0,48	0,55	disease	0,64	neutral	0,35	disease	0,58	disease	0,63	3	neutral	0,57	deleterious	0,7	neutral	-6	neutral	0,22	medium_impact	0,86	medium_impact	0,15	medium_impact	-0,25	0,52	0,8	8,13	10,88	P	0,56	P	0,19	polymorphism	0,94	0,03	rs386829193	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13781	13781	T	A	MI.22344	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1445	482	I	N	aTc/aAc	8,42	1	0	possibly_damaging	0,47	neutral	0,32	neutral	0,88	deleterious	-3,01	deleterious	-2,81	low_impact	1,04	neutral	0,69	neutral	0,52	deleterious	4,37	24,1	0,45	0,55	disease	0,79	disease	0,77	disease	0,63	disease	0,78	6	neutral	0,64	neutral	0,43	neutral	-3	deleterious	0,69	medium_impact	-0,7	medium_impact	0,05	medium_impact	-0,25	0,57	0,8	8,13	10,88	N	0,49	N	0,51	polymorphism	0,84	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13782	13782	C	A	MI.22345	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1446	482	I	M	atC/atA	4,52	1	0	benign	0,02	neutral	0,23	neutral	1,19	neutral	1,34	neutral	3,38	neutral_impact	-2,8	neutral	0,82	neutral	0,94	neutral	-0,63	0,1	0,67	0,7	neutral	0,42	neutral	0,05	neutral	0,18	neutral	0,26	5	neutral	0,76	deleterious	0,61	neutral	-6	neutral	0,15	medium_impact	0,86	medium_impact	-0,06	low_impact	-3,76	0,71	0,85	8,13	10,88	P	0,57	P	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13782	13782	C	G	MI.22346	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1446	482	I	M	atC/atG	4,52	1	0	benign	0,02	neutral	0,23	neutral	1,19	neutral	1,34	neutral	3,38	neutral_impact	-2,8	neutral	0,82	neutral	0,94	neutral	-1,07	0,01	0,67	0,7	neutral	0,42	neutral	0,05	neutral	0,18	neutral	0,26	5	neutral	0,76	deleterious	0,61	neutral	-6	neutral	0,15	medium_impact	0,86	medium_impact	-0,06	low_impact	-3,76	0,71	0,85	8,13	10,88	P	0,57	P	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13783	13783	C	G	MI.22347	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1447	483	P	A	Ccc/Gcc	0,4	0,98	0	probably_damaging	1	neutral	0,51	neutral	0,39	deleterious	-3,35	deleterious	-7,18	medium_impact	3,34	neutral	0,6	damaging	0,1	deleterious	3,22	22,7	0,42	0,55	disease	0,54	neutral	0,5	disease	0,67	disease	0,59	2	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,24	medium_impact	1,85	0,77	0,85	27,53	7,11	N	0,38	N	0,73	disease_causing	0,98	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13783	13783	C	A	MI.22348	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1447	483	P	T	Ccc/Acc	0,4	0,98	0	probably_damaging	1	neutral	0,43	neutral	0,41	deleterious	-3,14	deleterious	-7,18	medium_impact	2,91	damaging	0,52	damaging	0,06	deleterious	3,78	23,4	0,39	0,5	disease	0,56	disease	0,69	disease	0,65	disease	0,54	1	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,17	medium_impact	1,46	0,7	0,85	27,53	7,11	N	0,33	N	0,91	disease_causing	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13783	13783	C	T	MI.22349	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1447	483	P	S	Ccc/Tcc	0,4	0,98	0	probably_damaging	1	neutral	0,42	neutral	0,52	neutral	-1,97	deleterious	-7,18	medium_impact	2,84	neutral	0,63	damaging	0,1	deleterious	3,96	23,6	0,56	0,6	neutral	0,45	disease	0,73	disease	0,64	disease	0,53	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,16	medium_impact	1,39	0,23	0,8	27,53	7,11	N	0,34	N	0,78	disease_causing	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6073	6073	T	C	MI.2235	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	170	57	I	T	aTc/aCc	-0,11	0	0	benign	0,33	deleterious	0,02	neutral	2,66	neutral	-1,54	deleterious	-2,78	medium_impact	3,08	neutral	0,62	damaging	0,13	neutral	1,56	13,63	0,26	0,55	neutral	0,47	disease	0,81	disease	0,56	disease	0,69	4	neutral	0,98	neutral	0,35	deleterious	1	neutral	0,43	medium_impact	-0,47	medium_impact	-0,75	medium_impact	1,75	0,61	0,9	5,26	53,05	N	0,28	N	0,8	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13784	13784	C	A	MI.22350	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1448	483	P	H	cCc/cAc	4,29	1	0	probably_damaging	1	neutral	0,54	neutral	0,34	deleterious	-5,04	deleterious	-8,07	medium_impact	3,34	damaging	0,58	damaging	0,07	deleterious	4,12	23,8	0,35	0,5	disease	0,51	disease	0,79	disease	0,76	disease	0,74	5	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,27	medium_impact	1,85	0,57	0,8	27,53	7,11	N	0,4	N	0,72	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13784	13784	C	G	MI.22351	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1448	483	P	R	cCc/cGc	4,29	1	0	probably_damaging	1	neutral	0,35	neutral	0,35	deleterious	-4,61	deleterious	-8,08	high_impact	3,88	damaging	0,57	damaging	0,1	deleterious	3,75	23,3	0,32	0,5	disease	0,63	disease	0,86	disease	0,82	disease	0,84	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,08	high_impact	2,34	0,68	0,85	27,53	7,11	P	0,52	P	0,64	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13784	13784	C	T	MI.22352	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1448	483	P	L	cCc/cTc	4,29	1	0	probably_damaging	1	neutral	0,68	neutral	0,34	deleterious	-4,89	deleterious	-8,98	high_impact	3,88	damaging	0,59	damaging	0,07	deleterious	4,53	24,3	0,45	0,55	disease	0,56	disease	0,83	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,41	high_impact	2,34	0,75	0,85	27,53	7,11	N	0,42	N	0,97	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13786	13786	C	T	MI.22353	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1450	484	L	F	Ctc/Ttc	-20	0	0	benign	0,03	neutral	0,7	neutral	0,87	neutral	-1,06	neutral	-0,82	neutral_impact	0,65	neutral	0,81	neutral	0,94	neutral	1,77	14,79	0,54	0,6	NA	NA	neutral	0,36	neutral	0,25	neutral	0,16	7	neutral	0,25	deleterious	0,84	neutral	-6	deleterious	0,68	medium_impact	0,69	medium_impact	0,44	medium_impact	-0,61	0,63	0,8	25,7	14,61	N	0,32	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13786	13786	C	G	MI.22354	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1450	484	L	V	Ctc/Gtc	-20	0	0	benign	0,27	neutral	0,5	neutral	0,9	neutral	-0,7	neutral	-0,77	low_impact	1,83	neutral	0,81	neutral	0,78	neutral	1,42	12,89	0,48	0,55	NA	NA	neutral	0,28	neutral	0,38	neutral	0,16	7	neutral	0,4	deleterious	0,62	neutral	-6	deleterious	0,57	medium_impact	-0,34	medium_impact	0,23	medium_impact	0,47	0,6	0,8	25,7	14,61	N	0,32	N	0,19	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13786	13786	C	A	MI.22355	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1450	484	L	I	Ctc/Atc	-20	0	0	benign	0,37	neutral	0,41	neutral	0,88	neutral	-0,99	neutral	-0,55	low_impact	1,28	neutral	0,82	neutral	0,93	deleterious	2,28	18,04	0,51	0,6	NA	NA	neutral	0,22	neutral	0,25	neutral	0,17	7	neutral	0,52	deleterious	0,52	neutral	-6	deleterious	0,6	medium_impact	-0,53	medium_impact	0,15	medium_impact	-0,03	0,7	0,85	25,7	14,61	N	0,43	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13787	13787	T	C	MI.22356	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1451	484	L	P	cTc/cCc	-6,94	0	0	benign	0,03	neutral	0,24	neutral	0,81	neutral	-1,88	neutral	-2,08	neutral_impact	0,1	neutral	0,86	neutral	0,98	deleterious	0,45	7,01	0,22	0,45	NA	NA	neutral	0,4	neutral	0,47	neutral	0,14	7	neutral	0,75	deleterious	0,61	neutral	-6	neutral	0,18	medium_impact	0,69	medium_impact	-0,04	low_impact	-1,11	0,57	0,8	25,7	14,61	N	0,35	N	0,1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13787	13787	T	G	MI.22357	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1451	484	L	R	cTc/cGc	-6,94	0	0	possibly_damaging	0,59	neutral	0,35	neutral	0,76	deleterious	-3,47	neutral	-2,25	medium_impact	2,52	neutral	0,7	neutral	0,48	deleterious	2,68	20,7	0,3	0,45	NA	NA	disease	0,75	disease	0,57	disease	0,72	4	neutral	0,67	neutral	0,38	NA	0	deleterious	0,77	medium_impact	-0,9	medium_impact	0,08	medium_impact	1,1	0,65	0,8	25,7	14,61	N	0,3	N	0,31	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13787	13787	T	A	MI.22358	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1451	484	L	H	cTc/cAc	-6,94	0	0	benign	0,02	neutral	0,54	neutral	0,76	deleterious	-3,55	neutral	-1,77	low_impact	1,28	neutral	0,85	neutral	0,98	deleterious	2,17	17,3	0,29	0,45	NA	NA	neutral	0,48	neutral	0,38	neutral	0,32	4	neutral	0,44	deleterious	0,76	neutral	-6	deleterious	0,71	medium_impact	0,86	medium_impact	0,27	medium_impact	-0,03	0,68	0,85	25,7	14,61	N	0,3	N	0,04	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13789	13789	T	A	MI.22359	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1453	485	Y	N	Tac/Aac	-20	0	0,01	probably_damaging	0,92	neutral	0,36	neutral	0,9	neutral	-1,45	deleterious	-5,69	low_impact	1,7	neutral	0,81	neutral	0,62	deleterious	2,98	22,2	0,44	0,55	disease	0,64	neutral	0,49	disease	0,51	disease	0,57	1	neutral	0,93	neutral	0,22	neutral	-2	deleterious	0,75	low_impact	-1,75	medium_impact	0,1	medium_impact	0,35	0,33	0,8	19,57	16,38	N	0,32	N	0,76	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6073	6073	T	G	MI.2236	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	170	57	I	S	aTc/aGc	-0,11	0	0	possibly_damaging	0,62	deleterious	0	neutral	2,66	neutral	-1,42	deleterious	-3,47	medium_impact	2,9	neutral	0,63	damaging	0,13	deleterious	3,72	23,3	0,17	0,55	disease	0,52	disease	0,89	disease	0,57	disease	0,75	5	deleterious	1	neutral	0,19	deleterious	4	deleterious	0,55	medium_impact	-0,96	low_impact	-1,48	medium_impact	1,58	0,56	0,9	5,26	53,05	N	0,27	N	0,71	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13789	13789	T	G	MI.22360	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1453	485	Y	D	Tac/Gac	-20	0	0,01	probably_damaging	0,97	neutral	0,19	neutral	0,87	neutral	-2,35	deleterious	-6,77	medium_impact	2,25	neutral	0,76	neutral	0,44	deleterious	3,94	23,5	0,37	0,5	disease	0,67	disease	0,61	disease	0,63	disease	0,73	5	deleterious	0,98	neutral	0,11	deleterious	1	deleterious	0,79	low_impact	-2,18	medium_impact	-0,12	medium_impact	0,85	0,45	0,8	19,57	16,38	N	0,34	N	0,88	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13789	13789	T	C	MI.22361	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1453	485	Y	H	Tac/Cac	-20	0	0,01	benign	0,17	neutral	0,5	neutral	0,87	neutral	-2,46	neutral	-1,8	neutral_impact	0,12	neutral	0,84	neutral	0,98	deleterious	2,06	16,59	0,55	0,6	disease	0,53	neutral	0,3	neutral	0,45	neutral	0,36	3	neutral	0,4	deleterious	0,67	neutral	-6	deleterious	0,71	medium_impact	-0,09	medium_impact	0,23	low_impact	-1,09	0,32	0,8	19,57	16,38	N	0,28	N	0,39	polymorphism	1	0,07	rs28359179	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13790	13790	A	T	MI.22362	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1454	485	Y	F	tAc/tTc	-4,87	0	0	probably_damaging	0,92	neutral	0,72	neutral	0,97	neutral	-0,31	deleterious	-3,18	neutral_impact	0,66	neutral	0,83	neutral	0,87	deleterious	2,74	21,1	0,5	0,6	neutral	0,41	neutral	0,3	neutral	0,34	neutral	0,44	1	neutral	0,91	neutral	0,4	neutral	-2	deleterious	0,69	low_impact	-1,75	medium_impact	0,46	medium_impact	-0,6	0,31	0,8	19,57	16,38	N	0,23	N	0,25	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13790	13790	A	G	MI.22363	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1454	485	Y	C	tAc/tGc	-4,87	0	0	probably_damaging	0,99	neutral	0,15	neutral	0,85	deleterious	-3,35	deleterious	-6,7	medium_impact	2,25	neutral	0,76	neutral	0,38	deleterious	4,09	23,7	0,36	0,5	disease	0,8	disease	0,61	disease	0,54	disease	0,67	3	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,77	low_impact	-2,64	medium_impact	-0,18	medium_impact	0,85	0,13	0,8	19,57	16,38	N	0,28	N	0,82	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13790	13790	A	C	MI.22364	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1454	485	Y	S	tAc/tCc	-4,87	0	0	probably_damaging	0,96	neutral	0,45	neutral	0,93	neutral	-0,77	deleterious	-6,08	neutral_impact	0,38	neutral	0,85	neutral	0,9	deleterious	2,92	21,9	0,35	0,5	neutral	0,47	neutral	0,29	neutral	0,43	neutral	0,44	1	neutral	0,96	neutral	0,25	neutral	-2	deleterious	0,71	low_impact	-2,06	medium_impact	0,18	medium_impact	-0,86	0,37	0,8	19,57	16,38	N	0,33	N	0,79	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13792	13792	C	A	MI.22365	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1456	486	L	M	Cta/Ata	-6,71	0	0	probably_damaging	0,98	neutral	0,53	neutral	0,68	neutral	-2	neutral	-1,22	neutral_impact	0,79	neutral	0,8	neutral	0,94	deleterious	2,83	21,5	0,4	0,5	NA	NA	neutral	0,25	neutral	0,34	neutral	0,18	6	deleterious	0,98	neutral	0,28	neutral	-2	deleterious	0,71	low_impact	-2,35	medium_impact	0,26	medium_impact	-0,48	0,78	0,85	15,59	14,45	N	0,27	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13792	13792	C	G	MI.22366	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1456	486	L	V	Cta/Gta	-6,71	0	0	possibly_damaging	0,76	neutral	0,51	neutral	0,69	neutral	-1,96	neutral	-2,02	medium_impact	2,15	neutral	0,75	neutral	0,32	deleterious	3,47	23	0,47	0,55	NA	NA	neutral	0,46	disease	0,58	neutral	0,41	2	neutral	0,74	neutral	0,38	NA	0	deleterious	0,75	low_impact	-1,22	medium_impact	0,24	medium_impact	0,76	0,53	0,8	15,59	14,45	N	0,26	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13793	13793	T	A	MI.22367	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1457	486	L	Q	cTa/cAa	-3,04	0	0	probably_damaging	1	neutral	0,27	neutral	0,6	deleterious	-3,69	deleterious	-4,87	medium_impact	2,95	neutral	0,71	damaging	0,14	deleterious	4,22	23,9	0,32	0,5	NA	NA	disease	0,77	disease	0,59	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	-0,01	medium_impact	1,49	0,63	0,8	15,59	14,45	N	0,3	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13793	13793	T	G	MI.22368	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1457	486	L	R	cTa/cGa	-3,04	0	0	probably_damaging	1	neutral	0,31	neutral	0,59	deleterious	-4,17	deleterious	-4,96	medium_impact	2,95	neutral	0,65	damaging	0,1	deleterious	4,27	24	0,33	0,5	NA	NA	disease	0,88	disease	0,72	disease	0,79	6	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,88	low_impact	-3,6	medium_impact	0,04	medium_impact	1,49	0,51	0,8	15,59	14,45	N	0,26	N	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13793	13793	T	C	MI.22369	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1457	486	L	P	cTa/cCa	-3,04	0	0	probably_damaging	1	neutral	0,23	neutral	0,58	deleterious	-4,87	deleterious	-5,73	medium_impact	2,95	neutral	0,63	damaging	0,14	deleterious	4,02	23,6	0,26	0,45	NA	NA	disease	0,86	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,89	low_impact	-3,6	medium_impact	-0,06	medium_impact	1,49	0,55	0,8	15,59	14,45	N	0,24	N	0,89	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6073	6073	T	A	MI.2237	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	170	57	I	N	aTc/aAc	-0,11	0	0	possibly_damaging	0,88	deleterious	0	neutral	2,6	deleterious	-3,38	deleterious	-4,1	high_impact	4,53	damaging	0,59	damaging	0,11	deleterious	4,11	23,7	0,13	0,55	disease	0,68	disease	0,87	disease	0,61	disease	0,74	5	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,78	low_impact	-1,57	low_impact	-1,48	high_impact	3,08	0,64	0,9	5,26	53,05	N	0,43	N	0,82	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13795	13795	A	G	MI.22370	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1459	487	K	E	Aaa/Gaa	-4,64	0	0	probably_damaging	1	neutral	0,29	neutral	-0,23	deleterious	-5,15	deleterious	-3,59	high_impact	3,93	damaging	0,54	damaging	0,13	deleterious	4,12	23,8	0,42	0,5	neutral	0,46	disease	0,86	disease	0,79	disease	0,8	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,02	high_impact	2,39	0,58	0,8	27,86	7,2	N	0,42	N	0,84	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13795	13795	A	C	MI.22371	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1459	487	K	Q	Aaa/Caa	-4,64	0	0	probably_damaging	1	neutral	0,3	neutral	-0,24	deleterious	-5,38	deleterious	-3,59	high_impact	3,93	damaging	0,5	damaging	0,11	deleterious	3,57	23,1	0,44	0,55	disease	0,55	disease	0,83	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,03	high_impact	2,39	0,6	0,8	27,86	7,2	N	0,38	N	0,82	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13796	13796	A	C	MI.22372	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1460	487	K	T	aAa/aCa	8,42	1	0	probably_damaging	1	neutral	0,57	neutral	-0,24	deleterious	-5,25	deleterious	-5,39	high_impact	3,93	damaging	0,48	damaging	0,14	deleterious	3,69	23,3	0,29	0,45	disease	0,61	disease	0,79	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,3	high_impact	2,39	0,51	0,8	27,86	7,2	P	0,58	P	0,75	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13796	13796	A	T	MI.22373	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1460	487	K	M	aAa/aTa	8,42	1	0	probably_damaging	1	neutral	0,27	neutral	-0,28	deleterious	-7,72	deleterious	-5,39	high_impact	3,93	damaging	0,54	damaging	0,09	deleterious	3,92	23,5	0,26	0,45	disease	0,57	disease	0,84	disease	0,76	disease	0,8	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	-0,01	high_impact	2,39	0,41	0,8	27,86	7,2	P	0,52	P	0,4	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13797	13797	A	T	MI.22374	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1461	487	K	N	aaA/aaT	8,42	1	0	probably_damaging	1	neutral	0,37	neutral	-0,23	deleterious	-5,03	deleterious	-4,49	high_impact	3,93	damaging	0,56	damaging	0,09	deleterious	3,94	23,5	0,55	0,6	disease	0,63	disease	0,84	disease	0,77	disease	0,8	6	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,11	high_impact	2,39	0,58	0,8	27,86	7,2	P	0,62	P	0,63	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13797	13797	A	C	MI.22375	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1461	487	K	N	aaA/aaC	8,42	1	0	probably_damaging	1	neutral	0,37	neutral	-0,23	deleterious	-5,03	deleterious	-4,49	high_impact	3,93	damaging	0,56	damaging	0,09	deleterious	3,89	23,5	0,55	0,6	disease	0,63	disease	0,84	disease	0,77	disease	0,8	6	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,11	high_impact	2,39	0,58	0,8	27,86	7,2	P	0,6	P	0,63	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13798	13798	C	A	MI.22376	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1462	488	L	I	Ctc/Atc	3,15	0,99	0	possibly_damaging	0,66	neutral	0,44	neutral	0,78	neutral	-1,42	neutral	-1,1	low_impact	1,72	neutral	0,78	neutral	0,94	deleterious	3,22	22,7	0,44	0,55	neutral	0,33	neutral	0,33	neutral	0,3	neutral	0,47	1	neutral	0,66	neutral	0,39	neutral	-3	deleterious	0,68	low_impact	-1,02	medium_impact	0,18	medium_impact	0,37	0,74	0,85	10,45	11,49	N	0,48	N	0,29	disease_causing	0,59	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13798	13798	C	T	MI.22377	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1462	488	L	F	Ctc/Ttc	3,15	0,99	0	benign	0,12	neutral	0,73	neutral	0,7	neutral	-2,56	neutral	-1,72	medium_impact	2,9	neutral	0,83	neutral	0,94	deleterious	2,97	22,1	0,49	0,55	disease	0,6	disease	0,62	neutral	0,49	disease	0,51	0	neutral	0,16	deleterious	0,81	neutral	-3	deleterious	0,75	medium_impact	0,08	medium_impact	0,47	medium_impact	1,45	0,63	0,8	10,45	11,49	N	0,43	N	0,29	disease_causing	0,93	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13798	13798	C	G	MI.22378	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1462	488	L	V	Ctc/Gtc	3,15	0,99	0	possibly_damaging	0,66	neutral	0,56	neutral	0,78	neutral	-1,43	neutral	-1,63	medium_impact	2,48	neutral	0,82	neutral	0,8	deleterious	3,49	23,1	0,44	0,55	neutral	0,36	neutral	0,48	neutral	0,36	neutral	0,48	1	neutral	0,61	neutral	0,45	NA	0	deleterious	0,69	low_impact	-1,02	medium_impact	0,29	medium_impact	1,06	0,62	0,8	10,45	11,49	N	0,38	N	0,3	disease_causing	0,72	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13799	13799	T	A	MI.22379	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1463	488	L	H	cTc/cAc	-3,96	0	0	benign	0,18	neutral	0,52	neutral	0,64	deleterious	-4,59	deleterious	-4,29	medium_impact	3,44	neutral	0,74	neutral	0,47	deleterious	4,36	24,1	0,24	0,45	disease	0,72	disease	0,77	disease	0,66	disease	0,72	4	neutral	0,38	deleterious	0,67	neutral	-3	deleterious	0,8	medium_impact	-0,12	medium_impact	0,25	medium_impact	1,94	0,69	0,85	10,45	11,49	N	0,27	N	0,77	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6074	6074	C	G	MI.2238	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	171	57	I	M	atC/atG	7,53	0,97	0	possibly_damaging	0,79	neutral	0,07	neutral	2,66	neutral	-1,43	neutral	-1,46	low_impact	1,7	neutral	0,63	damaging	0,19	deleterious	2,93	22	0,29	0,55	neutral	0,46	disease	0,57	neutral	0,34	neutral	0,48	1	neutral	0,95	neutral	0,14	neutral	-3	deleterious	0,6	low_impact	-1,3	medium_impact	-0,43	medium_impact	0,47	0,82	0,9	5,26	53,05	P	0,52	P	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13799	13799	T	G	MI.22380	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1463	488	L	R	cTc/cGc	-3,96	0	0	probably_damaging	0,91	neutral	0,34	neutral	0,65	deleterious	-4,04	deleterious	-3,86	medium_impact	3,44	neutral	0,67	neutral	0,41	deleterious	4,34	24	0,16	0,45	disease	0,65	disease	0,88	disease	0,7	disease	0,78	6	neutral	0,92	neutral	0,22	deleterious	1	deleterious	0,85	low_impact	-1,7	medium_impact	0,07	medium_impact	1,94	0,73	0,85	10,45	11,49	N	0,3	N	0,62	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13799	13799	T	C	MI.22381	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1463	488	L	P	cTc/cCc	-3,96	0	0	probably_damaging	0,95	neutral	0,29	neutral	0,64	deleterious	-4,64	deleterious	-4,61	medium_impact	3,44	neutral	0,61	neutral	0,37	deleterious	4,08	23,7	0,15	0,4	disease	0,7	disease	0,87	disease	0,71	disease	0,79	6	neutral	0,96	neutral	0,17	deleterious	1	deleterious	0,86	low_impact	-1,96	medium_impact	0,02	medium_impact	1,94	0,6	0,8	10,45	11,49	N	0,29	N	0,9	disease_causing	0,86	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13801	13801	A	T	MI.22382	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1465	489	T	S	Aca/Tca	-12,67	0	0	benign	0,03	neutral	0,43	neutral	0,98	neutral	-0,29	neutral	-1,56	neutral_impact	0,34	neutral	0,89	neutral	0,96	neutral	-0,24	0,89	0,54	0,6	neutral	0,31	neutral	0,29	neutral	0,27	neutral	0,44	1	neutral	0,54	deleterious	0,7	neutral	-6	deleterious	0,45	medium_impact	0,69	medium_impact	0,17	medium_impact	-0,89	0,75	0,85	19,57	15,11	N	0,47	N	0,02	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13801	13801	A	G	MI.22383	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1465	489	T	A	Aca/Gca	-12,67	0	0	benign	0,01	neutral	0,53	neutral	1,08	neutral	0,68	neutral	-2,31	neutral_impact	0,04	neutral	0,76	neutral	0,92	neutral	-0,89	0,03	0,58	0,65	neutral	0,35	neutral	0,08	neutral	0,26	neutral	0,21	6	neutral	0,46	deleterious	0,76	neutral	-6	neutral	0,13	medium_impact	1,15	medium_impact	0,26	low_impact	-1,17	0,49	0,8	19,57	15,11	N	0,41	N	0,06	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13801	13801	A	C	MI.22384	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1465	489	T	P	Aca/Cca	-12,67	0	0	possibly_damaging	0,66	neutral	0,26	neutral	0,88	neutral	-2,97	deleterious	-3,63	medium_impact	2,77	neutral	0,62	neutral	0,31	deleterious	3,48	23,1	0,22	0,45	disease	0,8	disease	0,88	disease	0,69	disease	0,82	6	neutral	0,78	neutral	0,3	NA	0	deleterious	0,84	low_impact	-1,02	medium_impact	-0,02	medium_impact	1,33	0,75	0,85	19,57	15,11	N	0,28	N	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13802	13802	C	A	MI.22385	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1466	489	T	K	aCa/aAa	-1,44	0	0	benign	0,37	neutral	0,31	neutral	0,91	neutral	-1,47	deleterious	-3,31	medium_impact	2,77	neutral	0,76	neutral	0,41	deleterious	4,31	24	0,25	0,45	disease	0,65	disease	0,81	disease	0,65	disease	0,78	6	neutral	0,63	deleterious	0,47	neutral	-3	deleterious	0,71	medium_impact	-0,53	medium_impact	0,04	medium_impact	1,33	0,75	0,85	19,57	15,11	N	0,28	N	0,67	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13802	13802	C	T	MI.22386	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1466	489	T	M	aCa/aTa	-1,44	0	0	benign	0,12	neutral	0,23	neutral	1,02	neutral	0,16	neutral	-2,46	low_impact	1,1	neutral	0,83	neutral	0,98	deleterious	2,77	21,2	0,38	0,5	disease	0,66	disease	0,54	neutral	0,34	disease	0,51	0	neutral	0,74	deleterious	0,56	neutral	-6	deleterious	0,73	medium_impact	0,08	medium_impact	-0,06	medium_impact	-0,2	0,75	0,85	19,57	15,11	N	0,36	N	0,8	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13804	13804	G	A	MI.22387	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1468	490	A	T	Gcc/Acc	-7,17	0	0	probably_damaging	1	neutral	0,43	neutral	0,66	neutral	-1,65	deleterious	-3,02	medium_impact	2,1	neutral	0,65	neutral	0,65	deleterious	4,28	24	0,48	0,55	neutral	0,5	disease	0,75	disease	0,54	disease	0,51	0	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,17	medium_impact	0,72	0,74	0,85	9,95	7,25	N	0,27	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13804	13804	G	T	MI.22388	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1468	490	A	S	Gcc/Tcc	-7,17	0	0	probably_damaging	1	neutral	0,49	neutral	0,53	deleterious	-3,28	neutral	-2,44	medium_impact	3,46	neutral	0,7	neutral	0,44	deleterious	3,81	23,4	0,39	0,5	neutral	0,43	disease	0,83	disease	0,61	disease	0,71	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,22	medium_impact	1,96	0,92	0,95	9,95	7,25	N	0,29	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13804	13804	G	C	MI.22389	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1468	490	A	P	Gcc/Ccc	-7,17	0	0	probably_damaging	1	neutral	0,27	neutral	0,55	neutral	-2,97	deleterious	-4,24	medium_impact	2,7	damaging	0,58	neutral	0,61	deleterious	3,96	23,6	0,1	0,4	disease	0,53	disease	0,85	disease	0,68	disease	0,53	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,01	medium_impact	1,26	0,83	0,85	9,95	7,25	N	0,31	N	0,96	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6074	6074	C	A	MI.2239	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	171	57	I	M	atC/atA	7,53	0,97	0	possibly_damaging	0,79	neutral	0,07	neutral	2,66	neutral	-1,43	neutral	-1,46	low_impact	1,7	neutral	0,63	damaging	0,19	deleterious	3,44	23	0,29	0,55	neutral	0,46	disease	0,57	neutral	0,34	neutral	0,48	1	neutral	0,95	neutral	0,14	neutral	-3	deleterious	0,6	low_impact	-1,3	medium_impact	-0,43	medium_impact	0,47	0,82	0,9	5,26	53,05	P	0,53	P	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13805	13805	C	G	MI.22390	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1469	490	A	G	gCc/gGc	4,06	1	0	probably_damaging	1	neutral	0,36	neutral	0,54	deleterious	-3,25	deleterious	-3,47	high_impact	3,8	neutral	0,69	neutral	0,54	deleterious	4,09	23,7	0,26	0,45	disease	0,69	disease	0,8	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,1	high_impact	2,27	0,87	0,9	9,95	7,25	N	0,5	N	0,82	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13805	13805	C	A	MI.22391	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1469	490	A	D	gCc/gAc	4,06	1	0	probably_damaging	1	neutral	0,2	neutral	0,5	deleterious	-4,57	deleterious	-5,07	high_impact	3,8	neutral	0,66	neutral	0,41	deleterious	4,74	24,7	0,12	0,4	disease	0,59	disease	0,93	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,1	high_impact	2,27	0,77	0,85	9,95	7,25	P	0,51	P	0,95	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13805	13805	C	T	MI.22392	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1469	490	A	V	gCc/gTc	4,06	1	0	probably_damaging	1	neutral	0,56	neutral	0,59	neutral	-2,3	deleterious	-3,34	high_impact	3,8	neutral	0,66	neutral	0,47	deleterious	4,56	24,4	0,35	0,5	disease	0,59	disease	0,84	disease	0,6	disease	0,72	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,29	high_impact	2,27	0,85	0,9	9,95	7,25	N	0,48	N	0,76	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13807	13807	C	G	MI.22393	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1471	491	L	V	Ctc/Gtc	-7,4	0	0	probably_damaging	1	neutral	0,51	neutral	0,5	neutral	-2,43	neutral	-2,04	medium_impact	2,66	neutral	0,81	neutral	0,68	deleterious	3,51	23,1	0,35	0,5	disease	0,52	disease	0,51	neutral	0,43	neutral	0,46	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,24	medium_impact	1,23	0,73	0,85	3,98	8,23	N	0,27	N	0,81	polymorphism	0,85	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13807	13807	C	A	MI.22394	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1471	491	L	I	Ctc/Atc	-7,4	0	0	probably_damaging	1	neutral	0,47	neutral	0,56	neutral	-1,93	neutral	-1,27	low_impact	1,2	neutral	0,8	neutral	0,91	deleterious	3,09	22,5	0,32	0,5	neutral	0,4	neutral	0,25	neutral	0,36	neutral	0,43	2	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,2	medium_impact	-0,11	0,79	0,85	3,98	8,23	N	0,33	N	0,85	polymorphism	0,91	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13807	13807	C	T	MI.22395	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1471	491	L	F	Ctc/Ttc	-7,4	0	0	probably_damaging	1	neutral	0,77	neutral	0,43	deleterious	-3,38	deleterious	-3,17	medium_impact	2,94	neutral	0,73	neutral	0,42	deleterious	4,08	23,7	0,37	0,5	disease	0,61	disease	0,68	disease	0,63	disease	0,62	2	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,52	medium_impact	1,48	0,75	0,85	3,98	8,23	N	0,19	N	0,99	polymorphism	0,54	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13808	13808	T	G	MI.22396	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1472	491	L	R	cTc/cGc	-0,98	0	0	probably_damaging	1	neutral	0,31	neutral	0,38	deleterious	-5,02	deleterious	-4,98	high_impact	3,63	damaging	0,58	damaging	0,26	deleterious	4,31	24	0,08	0,35	disease	0,78	disease	0,9	disease	0,75	disease	0,84	7	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,04	high_impact	2,11	0,78	0,85	3,98	8,23	N	0,33	N	1	disease_causing	0,56	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13808	13808	T	C	MI.22397	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1472	491	L	P	cTc/cCc	-0,98	0	0	probably_damaging	1	neutral	0,21	neutral	0,39	deleterious	-4,63	deleterious	-5,72	medium_impact	3,29	neutral	0,61	damaging	0,25	deleterious	4,02	23,6	0,1	0,4	disease	0,58	disease	0,86	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	-0,09	medium_impact	1,8	0,66	0,8	3,98	8,23	N	0,3	N	0,99	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13808	13808	T	A	MI.22398	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1472	491	L	H	cTc/cAc	-0,98	0	0	probably_damaging	1	neutral	0,44	neutral	0,38	deleterious	-5,59	deleterious	-5,75	high_impact	3,63	neutral	0,69	neutral	0,31	deleterious	4,25	23,9	0,13	0,4	disease	0,59	disease	0,81	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,18	high_impact	2,11	0,68	0,85	3,98	8,23	N	0,25	N	0,97	polymorphism	0,59	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13810	13810	G	C	MI.22399	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1474	492	A	P	Gct/Cct	-13,58	0	0	benign	0,29	neutral	0,23	neutral	0,9	neutral	-2,8	neutral	-2,25	low_impact	1,45	neutral	0,72	neutral	0,4	deleterious	2,2	17,54	0,09	0,35	disease	0,82	disease	0,82	disease	0,63	disease	0,79	6	neutral	0,72	deleterious	0,47	neutral	-6	deleterious	0,65	medium_impact	-0,38	medium_impact	-0,06	medium_impact	0,12	0,86	0,9	27,36	18,4	N	0,26	N	0,65	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8632	8632	T	G	MI.224	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	106	36	Y	D	Tat/Gat	-10,05	0	0	benign	0,17	neutral	0,19	neutral	4,44	neutral	1,74	neutral	-1,53	low_impact	1,05	neutral	0,9	neutral	0,49	deleterious	2,09	16,81	0,52	0,65	neutral	0,4	disease	0,63	disease	0,54	disease	0,64	3	neutral	0,78	deleterious	0,51	neutral	-6	neutral	0,27	medium_impact	-0,1	medium_impact	-0,06	medium_impact	-0,2	0,48	0,9	29,2	23,72	N	0,38	N	0,24	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6075	6075	G	C	MI.2240	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	172	58	V	L	Gtc/Ctc	-4,5	0	0	benign	0,04	neutral	0,05	neutral	2,9	neutral	0,61	neutral	-1,79	high_impact	3,6	neutral	0,61	neutral	0,53	neutral	1,49	13,25	0,23	0,55	neutral	0,24	disease	0,83	neutral	0,5	disease	0,7	4	neutral	0,95	deleterious	0,51	neutral	-2	neutral	0,26	medium_impact	0,54	medium_impact	-0,52	high_impact	2,23	0,74	0,9	1,75	6,95	N	0,44	N	0,55	polymorphism	0,97	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13810	13810	G	T	MI.22400	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1474	492	A	S	Gct/Tct	-13,58	0	0	benign	0,01	neutral	0,48	neutral	0,94	neutral	-1,07	neutral	-0,7	neutral_impact	-0,08	neutral	0,91	neutral	0,82	deleterious	0,49	7,34	0,36	0,5	disease	0,65	neutral	0,36	neutral	0,38	disease	0,61	2	neutral	0,51	deleterious	0,74	neutral	-6	neutral	0,18	medium_impact	1,15	medium_impact	0,21	low_impact	-1,28	0,87	0,9	27,36	18,4	N	0,33	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13810	13810	G	A	MI.22401	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1474	492	A	T	Gct/Act	-13,58	0	0	benign	0,01	neutral	0,52	neutral	1,01	neutral	0,07	neutral	-0,26	neutral_impact	-0,79	neutral	0,88	neutral	0,99	deleterious	0,32	5,84	0,45	0,55	disease	0,55	neutral	0,17	neutral	0,25	neutral	0,37	3	neutral	0,46	deleterious	0,76	neutral	-6	neutral	0,14	medium_impact	1,15	medium_impact	0,25	low_impact	-1,92	0,71	0,85	27,36	18,4	N	0,39	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13811	13811	C	G	MI.22402	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1475	492	A	G	gCt/gGt	-14,73	0	0	benign	0	neutral	0,44	neutral	0,92	neutral	-1,85	neutral	-2,03	neutral_impact	0,64	neutral	0,91	neutral	0,8	neutral	0,94	10,32	0,18	0,45	disease	0,63	neutral	0,42	neutral	0,38	disease	0,6	2	neutral	0,56	deleterious	0,72	neutral	-6	neutral	0,17	high_impact	2,1	medium_impact	0,18	medium_impact	-0,62	0,83	0,85	27,36	18,4	N	0,34	N	0,12	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13811	13811	C	A	MI.22403	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1475	492	A	D	gCt/gAt	-14,73	0	0	benign	0,11	neutral	0,21	neutral	0,9	deleterious	-3,39	deleterious	-2,62	low_impact	1,45	neutral	0,77	neutral	0,41	deleterious	2,71	20,8	0,11	0,4	disease	0,72	disease	0,77	disease	0,63	disease	0,77	5	neutral	0,76	deleterious	0,55	neutral	-6	deleterious	0,51	medium_impact	0,12	medium_impact	-0,09	medium_impact	0,12	0,77	0,85	27,36	18,4	N	0,27	N	0,55	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13811	13811	C	T	MI.22404	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1475	492	A	V	gCt/gTt	-14,73	0	0	benign	0,11	neutral	0,54	neutral	1,05	neutral	0,54	neutral	-0,25	neutral_impact	0,2	neutral	0,86	neutral	0,95	neutral	1,24	11,98	0,35	0,5	neutral	0,29	neutral	0,35	neutral	0,31	neutral	0,45	1	neutral	0,37	deleterious	0,72	neutral	-6	neutral	0,25	medium_impact	0,12	medium_impact	0,27	low_impact	-1,02	0,73	0,85	27,36	18,4	N	0,33	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13813	13813	G	C	MI.22405	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1477	493	V	L	Gtc/Ctc	-20	0	0	benign	0,12	neutral	0,82	neutral	0,62	neutral	-1,86	neutral	-1,94	low_impact	1,66	neutral	0,76	neutral	0,68	neutral	1,79	14,95	0,44	0,55	disease	0,55	disease	0,8	disease	0,51	disease	0,54	1	neutral	0,08	deleterious	0,85	neutral	-6	neutral	0,23	medium_impact	0,08	medium_impact	0,6	medium_impact	0,31	0,76	0,85	10,45	10,12	N	0,22	N	0,53	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13813	13813	G	A	MI.22406	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1477	493	V	I	Gtc/Atc	-20	0	0	benign	0,01	neutral	0,48	neutral	0,58	neutral	-2,22	neutral	-0,37	neutral_impact	0,74	neutral	0,82	neutral	0,94	deleterious	0,43	6,86	0,5	0,6	neutral	0,44	neutral	0,32	neutral	0,4	neutral	0,43	1	neutral	0,51	deleterious	0,74	neutral	-6	neutral	0,14	medium_impact	1,15	medium_impact	0,21	medium_impact	-0,53	0,78	0,85	10,45	10,12	N	0,39	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13813	13813	G	T	MI.22407	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1477	493	V	F	Gtc/Ttc	-20	0	0	possibly_damaging	0,5	neutral	0,78	neutral	0,52	deleterious	-3,15	deleterious	-3,68	medium_impact	2,55	neutral	0,73	neutral	0,66	deleterious	2,29	18,11	0,2	0,45	disease	0,59	disease	0,89	disease	0,65	disease	0,57	1	neutral	0,39	deleterious	0,64	NA	0	deleterious	0,55	medium_impact	-0,75	medium_impact	0,54	medium_impact	1,13	0,68	0,85	10,45	10,12	N	0,24	N	0,77	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13814	13814	T	C	MI.22408	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1478	493	V	A	gTc/gCc	-0,29	0	0	benign	0,01	neutral	0,62	neutral	0,56	neutral	-2,48	deleterious	-3,23	low_impact	1,94	neutral	0,81	neutral	0,76	neutral	1,66	14,19	0,3	0,45	disease	0,56	disease	0,56	disease	0,56	disease	0,5	0	neutral	0,37	deleterious	0,81	neutral	-6	neutral	0,19	medium_impact	1,15	medium_impact	0,35	medium_impact	0,57	0,41	0,8	10,45	10,12	N	0,26	N	0,06	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13814	13814	T	A	MI.22409	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1478	493	V	D	gTc/gAc	-0,29	0	0	possibly_damaging	0,55	neutral	0,24	neutral	0,46	deleterious	-5,96	deleterious	-5,57	medium_impact	3,35	neutral	0,68	neutral	0,37	deleterious	4,22	23,9	0,08	0,35	disease	0,89	disease	0,93	disease	0,75	disease	0,86	7	neutral	0,75	neutral	0,35	NA	0	deleterious	0,76	medium_impact	-0,83	medium_impact	-0,04	medium_impact	1,86	0,59	0,8	10,45	10,12	N	0,3	N	0,92	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6075	6075	G	A	MI.2241	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	172	58	V	I	Gtc/Atc	-4,5	0	0	benign	0,01	neutral	0,24	neutral	2,73	neutral	-0,83	neutral	-0,52	low_impact	1,75	damaging	0,55	neutral	0,6	deleterious	0,39	6,54	0,3	0,55	neutral	0,31	neutral	0,5	neutral	0,37	neutral	0,44	1	neutral	0,76	deleterious	0,62	neutral	-6	neutral	0,21	medium_impact	1,12	medium_impact	-0,09	medium_impact	0,52	0,68	0,9	1,75	6,95	N	0,47	N	0,24	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13814	13814	T	G	MI.22410	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1478	493	V	G	gTc/gGc	-0,29	0	0	benign	0,01	neutral	0,39	neutral	0,47	deleterious	-4,86	deleterious	-5,83	medium_impact	2,66	neutral	0,69	neutral	0,61	deleterious	2,13	17,03	0,17	0,45	disease	0,7	disease	0,87	disease	0,63	disease	0,74	5	neutral	0,6	deleterious	0,69	neutral	-3	deleterious	0,49	medium_impact	1,15	medium_impact	0,13	medium_impact	1,23	0,51	0,8	10,45	10,12	N	0,28	N	0,9	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13816	13816	A	C	MI.22411	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1480	494	T	P	Act/Cct	-13,81	0	0	probably_damaging	0,98	neutral	0,26	neutral	0,71	deleterious	-3,05	deleterious	-5,26	high_impact	3,68	neutral	0,66	neutral	0,3	deleterious	3,59	23,2	0,14	0,4	disease	0,82	disease	0,9	disease	0,74	disease	0,82	6	deleterious	0,98	neutral	0,14	deleterious	2	deleterious	0,87	low_impact	-2,35	medium_impact	-0,02	high_impact	2,16	0,76	0,85	4,15	9,95	N	0,31	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13816	13816	A	T	MI.22412	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1480	494	T	S	Act/Tct	-13,81	0	0	possibly_damaging	0,81	neutral	0,54	neutral	0,83	neutral	-1,13	deleterious	-3,38	low_impact	1,64	neutral	0,72	neutral	0,88	deleterious	2,33	18,34	0,47	0,55	neutral	0,41	neutral	0,49	neutral	0,38	neutral	0,45	1	neutral	0,79	neutral	0,37	neutral	-3	deleterious	0,72	low_impact	-1,34	medium_impact	0,27	medium_impact	0,3	0,8	0,85	4,15	9,95	N	0,33	N	0,52	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13816	13816	A	G	MI.22413	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1480	494	T	A	Act/Gct	-13,81	0	0	benign	0,12	neutral	0,63	neutral	0,74	neutral	-2,2	deleterious	-4,34	medium_impact	2,78	neutral	0,74	neutral	0,76	deleterious	3,62	23,2	0,62	0,65	neutral	0,39	disease	0,63	disease	0,58	neutral	0,49	0	neutral	0,27	deleterious	0,76	neutral	-3	deleterious	0,73	medium_impact	0,08	medium_impact	0,36	medium_impact	1,34	0,62	0,8	4,15	9,95	N	0,33	N	0,83	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13817	13817	C	A	MI.22414	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1481	494	T	N	aCt/aAt	2,69	0,93	0	probably_damaging	0,97	neutral	0,33	neutral	0,69	deleterious	-3,93	deleterious	-4,3	high_impact	3,68	neutral	0,73	neutral	0,45	deleterious	3,76	23,3	0,37	0,5	disease	0,7	disease	0,88	disease	0,63	disease	0,74	5	neutral	0,97	neutral	0,18	deleterious	2	deleterious	0,82	low_impact	-2,18	medium_impact	0,06	high_impact	2,16	0,8	0,85	4,15	9,95	N	0,41	N	0,88	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13817	13817	C	G	MI.22415	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1481	494	T	S	aCt/aGt	2,69	0,93	0	possibly_damaging	0,81	neutral	0,54	neutral	0,83	neutral	-1,13	deleterious	-3,38	low_impact	1,64	neutral	0,72	neutral	0,88	deleterious	2,56	19,84	0,47	0,55	neutral	0,41	neutral	0,49	neutral	0,38	neutral	0,45	1	neutral	0,79	neutral	0,37	neutral	-3	deleterious	0,72	low_impact	-1,34	medium_impact	0,27	medium_impact	0,3	0,8	0,85	4,15	9,95	N	0,34	N	0,52	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13817	13817	C	T	MI.22416	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1481	494	T	I	aCt/aTt	2,69	0,93	0	possibly_damaging	0,82	neutral	0,48	neutral	0,79	neutral	-1,58	deleterious	-5,29	medium_impact	2,88	neutral	0,72	neutral	0,66	deleterious	4,02	23,6	0,4	0,5	disease	0,63	disease	0,84	disease	0,59	disease	0,69	4	neutral	0,8	neutral	0,33	NA	0	deleterious	0,8	low_impact	-1,37	medium_impact	0,21	medium_impact	1,43	0,84	0,9	4,15	9,95	N	0,33	N	0,93	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13819	13819	T	A	MI.22417	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1483	495	F	I	Ttc/Atc	-5,56	0	0,01	benign	0	neutral	0,54	neutral	1,28	neutral	2,01	neutral	2,47	neutral_impact	-2,39	neutral	0,84	neutral	0,98	neutral	-0,12	1,57	0,26	0,45	neutral	0,26	neutral	0,07	neutral	0,19	neutral	0,27	5	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,27	low_impact	-3,39	0,68	0,85	11,61	10,25	N	0,42	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13819	13819	T	C	MI.22418	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1483	495	F	L	Ttc/Ctc	-5,56	0	0,01	benign	0	neutral	0,98	neutral	1,17	neutral	1,48	neutral	1,89	neutral_impact	-1,96	neutral	0,86	neutral	0,99	deleterious	0,8	9,48	0,47	0,55	neutral	0,24	neutral	0,27	neutral	0,26	neutral	0,42	2	neutral	0,01	deleterious	0,99	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	1,17	low_impact	-2,99	0,7	0,85	11,61	10,25	N	0,28	N	0,01	polymorphism	1	0	rs371771942	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13819	13819	T	G	MI.22419	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1483	495	F	V	Ttc/Gtc	-5,56	0	0,01	benign	0,01	neutral	0,66	neutral	1,06	neutral	0,69	neutral	1,86	neutral_impact	-0,52	neutral	0,85	neutral	0,97	neutral	1,07	11,04	0,29	0,45	neutral	0,3	neutral	0,35	neutral	0,27	neutral	0,45	1	neutral	0,33	deleterious	0,83	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,39	low_impact	-1,68	0,7	0,85	11,61	10,25	N	0,25	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6075	6075	G	T	MI.2242	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	172	58	V	F	Gtc/Ttc	-4,5	0	0	possibly_damaging	0,8	deleterious	0,01	neutral	2,81	neutral	0	deleterious	-3,06	medium_impact	2,75	damaging	0,58	neutral	0,47	deleterious	3,48	23,1	0,11	0,55	neutral	0,25	disease	0,95	disease	0,62	disease	0,8	6	deleterious	0,99	neutral	0,11	deleterious	4	deleterious	0,74	low_impact	-1,32	medium_impact	-0,92	medium_impact	1,44	0,58	0,9	1,75	6,95	N	0,32	N	0,86	polymorphism	0,73	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13820	13820	T	A	MI.22420	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1484	495	F	Y	tTc/tAc	-3,73	0	0	benign	0,26	neutral	1	neutral	0,93	neutral	-1,68	neutral	-0,83	low_impact	0,8	neutral	0,82	neutral	0,63	deleterious	2,54	19,72	0,34	0,5	disease	0,58	neutral	0,37	neutral	0,47	disease	0,62	2	neutral	0,26	deleterious	0,87	neutral	-6	neutral	0,41	medium_impact	-0,32	high_impact	1,89	medium_impact	-0,47	0,67	0,85	11,61	10,25	N	0,21	N	0,04	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13820	13820	T	C	MI.22421	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1484	495	F	S	tTc/tCc	-3,73	0	0	benign	0,01	neutral	0,56	neutral	0,96	neutral	-0,64	neutral	-1,38	neutral_impact	0,26	neutral	0,8	neutral	0,6	deleterious	2,38	18,67	0,21	0,45	disease	0,51	neutral	0,49	neutral	0,5	neutral	0,44	1	neutral	0,43	deleterious	0,78	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,29	medium_impact	-0,97	0,64	0,8	11,61	10,25	N	0,22	N	0,01	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13820	13820	T	G	MI.22422	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1484	495	F	C	tTc/tGc	-3,73	0	0	possibly_damaging	0,49	neutral	0,17	neutral	0,91	neutral	-2,49	neutral	-0,82	low_impact	0,8	neutral	0,75	neutral	0,48	deleterious	3,84	23,4	0,21	0,45	disease	0,77	disease	0,63	neutral	0,49	disease	0,52	0	neutral	0,81	neutral	0,34	neutral	-3	deleterious	0,63	medium_impact	-0,73	medium_impact	-0,15	medium_impact	-0,47	0,51	0,8	11,61	10,25	N	0,32	N	0,07	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13821	13821	C	G	MI.22423	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1485	495	F	L	ttC/ttG	0,4	0	0	benign	0	neutral	0,98	neutral	1,17	neutral	1,48	neutral	1,89	neutral_impact	-1,96	neutral	0,86	neutral	0,99	neutral	1,12	11,32	0,47	0,55	neutral	0,24	neutral	0,27	neutral	0,26	neutral	0,42	2	neutral	0,01	deleterious	0,99	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	1,17	low_impact	-2,99	0,7	0,85	11,61	10,25	N	0,28	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13821	13821	C	A	MI.22424	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1485	495	F	L	ttC/ttA	0,4	0	0	benign	0	neutral	0,98	neutral	1,17	neutral	1,48	neutral	1,89	neutral_impact	-1,96	neutral	0,86	neutral	0,99	neutral	1,45	13,05	0,47	0,55	neutral	0,24	neutral	0,27	neutral	0,26	neutral	0,42	2	neutral	0,01	deleterious	0,99	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	1,17	low_impact	-2,99	0,7	0,85	11,61	10,25	N	0,28	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13822	13822	C	A	MI.22425	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1486	496	L	M	Cta/Ata	-5,79	0	0	possibly_damaging	0,76	neutral	0,32	neutral	0,63	neutral	-2,71	neutral	-1,06	medium_impact	1,95	neutral	0,86	neutral	0,98	deleterious	2,55	19,81	0,33	0,5	disease	0,66	neutral	0,36	neutral	0,36	disease	0,63	3	neutral	0,8	neutral	0,28	NA	0	deleterious	0,72	low_impact	-1,22	medium_impact	0,05	medium_impact	0,58	0,83	0,85	7,13	9,14	N	0,43	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13822	13822	C	G	MI.22426	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1486	496	L	V	Cta/Gta	-5,79	0	0	possibly_damaging	0,9	neutral	0,59	neutral	0,77	neutral	-1,17	neutral	-1,68	medium_impact	2,04	neutral	0,79	neutral	0,81	deleterious	2,36	18,56	0,36	0,5	neutral	0,39	neutral	0,35	neutral	0,38	neutral	0,46	1	neutral	0,88	neutral	0,35	NA	0	deleterious	0,69	low_impact	-1,65	medium_impact	0,32	medium_impact	0,66	0,69	0,85	7,13	9,14	N	0,27	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13823	13823	T	C	MI.22427	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1487	496	L	P	cTa/cCa	-10,37	0	0	probably_damaging	1	neutral	0,2	neutral	0,57	deleterious	-5,07	deleterious	-4,94	medium_impact	3,37	damaging	0,57	neutral	0,31	deleterious	4,01	23,6	0,12	0,4	disease	0,87	disease	0,87	disease	0,71	disease	0,82	6	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,89	low_impact	-3,6	medium_impact	-0,1	medium_impact	1,88	0,62	0,8	7,13	9,14	N	0,29	N	0,98	polymorphism	0,99	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13823	13823	T	G	MI.22428	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1487	496	L	R	cTa/cGa	-10,37	0	0	probably_damaging	0,98	neutral	0,33	neutral	0,57	deleterious	-4,49	deleterious	-4,25	medium_impact	3,37	neutral	0,66	neutral	0,38	deleterious	4,27	24	0,1	0,4	disease	0,75	disease	0,87	disease	0,71	disease	0,79	6	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,88	low_impact	-2,35	medium_impact	0,06	medium_impact	1,88	0,66	0,8	7,13	9,14	N	0,29	N	0,97	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13823	13823	T	A	MI.22429	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1487	496	L	Q	cTa/cAa	-10,37	0	0	probably_damaging	0,99	neutral	0,27	neutral	0,57	deleterious	-4,65	deleterious	-4,16	medium_impact	3,37	neutral	0,74	neutral	0,51	deleterious	4,18	23,8	0,14	0,4	disease	0,82	disease	0,78	disease	0,59	disease	0,75	5	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,82	low_impact	-2,64	medium_impact	-0,01	medium_impact	1,88	0,68	0,85	7,13	9,14	N	0,32	N	0,94	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6076	6076	T	C	MI.2243	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	173	58	V	A	gTc/gCc	7,3	1	0	possibly_damaging	0,56	deleterious	0	neutral	2,68	neutral	-1,61	deleterious	-2,54	high_impact	4,38	neutral	0,65	neutral	0,59	deleterious	3,08	22,5	0,19	0,55	disease	0,67	disease	0,73	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,22	deleterious	5	deleterious	0,62	medium_impact	-0,86	low_impact	-1,48	high_impact	2,95	0,47	0,9	1,75	6,95	P	0,57	P	0,47	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13825	13825	G	C	MI.22430	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1489	497	G	R	Gga/Cga	-1,67	0	0	probably_damaging	1	neutral	0,35	neutral	-0,48	deleterious	-7,49	deleterious	-7,18	high_impact	3,86	damaging	0,57	damaging	0,22	deleterious	4	23,6	0,13	0,4	disease	0,75	disease	0,92	disease	0,82	disease	0,86	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	0,08	high_impact	2,32	0,76	0,85	28,86	7,18	N	0,37	N	1	polymorphism	0,96	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13825	13825	G	T	MI.22431	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1489	497	G	W	Gga/Tga	-1,67	0	0	probably_damaging	1	neutral	0,22	neutral	-0,49	deleterious	-10,48	deleterious	-7,18	high_impact	3,86	neutral	0,61	damaging	0,21	deleterious	4,51	24,3	0,16	0,45	disease	0,95	disease	0,92	disease	0,78	disease	0,89	8	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,6	medium_impact	-0,07	high_impact	2,32	0,44	0,8	28,86	7,18	N	0,35	N	1	polymorphism	0,93	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13826	13826	G	A	MI.22432	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1490	497	G	E	gGa/gAa	5,9	1	0	probably_damaging	1	neutral	0,32	neutral	-0,48	deleterious	-7	deleterious	-7,18	high_impact	3,86	neutral	0,62	damaging	0,24	deleterious	4,02	23,6	0,17	0,45	disease	0,66	disease	0,89	disease	0,82	disease	0,85	7	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,05	high_impact	2,32	0,65	0,8	28,86	7,18	P	0,55	P	1	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13826	13826	G	T	MI.22433	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1490	497	G	V	gGa/gTa	5,9	1	0	probably_damaging	1	neutral	0,52	neutral	-0,47	deleterious	-6,72	deleterious	-8,08	high_impact	3,86	damaging	0,59	damaging	0,27	deleterious	3,87	23,5	0,17	0,45	disease	0,65	disease	0,86	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	0,25	high_impact	2,32	0,62	0,8	28,86	7,18	P	0,53	P	0,98	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13826	13826	G	C	MI.22434	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1490	497	G	A	gGa/gCa	5,9	1	0	probably_damaging	1	neutral	0,52	neutral	-0,4	deleterious	-4,79	deleterious	-5,39	medium_impact	2,5	damaging	0,55	neutral	0,57	deleterious	3,18	22,7	0,36	0,5	disease	0,56	disease	0,66	disease	0,66	disease	0,52	0	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,25	medium_impact	1,08	0,83	0,9	28,86	7,18	N	0,47	N	0,79	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13828	13828	C	A	MI.22435	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1492	498	L	I	Ctt/Att	-20	0	0	possibly_damaging	0,64	neutral	0,45	neutral	0,81	neutral	-1	neutral	-0,34	low_impact	1,62	neutral	0,8	neutral	0,82	deleterious	2,71	20,9	0,38	0,5	neutral	0,28	neutral	0,28	neutral	0,29	neutral	0,45	1	neutral	0,64	neutral	0,41	neutral	-3	deleterious	0,49	medium_impact	-0,98	medium_impact	0,18	medium_impact	0,28	0,75	0,85	16,92	14,54	N	0,38	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13828	13828	C	G	MI.22436	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1492	498	L	V	Ctt/Gtt	-20	0	0	possibly_damaging	0,53	neutral	0,53	neutral	0,75	neutral	-1,46	neutral	-1,24	medium_impact	2,15	neutral	0,74	neutral	0,81	deleterious	3,11	22,5	0,4	0,5	neutral	0,35	neutral	0,41	neutral	0,33	neutral	0,46	1	neutral	0,5	deleterious	0,5	NA	0	deleterious	0,53	medium_impact	-0,8	medium_impact	0,26	medium_impact	0,76	0,78	0,85	16,92	14,54	N	0,36	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13828	13828	C	T	MI.22437	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1492	498	L	F	Ctt/Ttt	-20	0	0	benign	0,05	neutral	0,78	neutral	0,67	neutral	-2,58	neutral	3,69	neutral_impact	0,49	neutral	0,89	neutral	0,95	neutral	-0,18	1,2	0,43	0,55	neutral	0,34	neutral	0,29	neutral	0,31	neutral	0,46	1	neutral	0,14	deleterious	0,87	neutral	-6	neutral	0,17	medium_impact	0,47	medium_impact	0,54	medium_impact	-0,76	0,7	0,85	16,92	14,54	N	0,3	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13829	13829	T	C	MI.22438	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1493	498	L	P	cTt/cCt	-0,75	0	0	probably_damaging	0,96	neutral	0,24	neutral	0,61	deleterious	-4,79	deleterious	-4,1	medium_impact	3,3	damaging	0,53	neutral	0,39	deleterious	4,05	23,7	0,13	0,4	disease	0,54	disease	0,87	disease	0,69	disease	0,77	5	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,83	low_impact	-2,06	medium_impact	-0,04	medium_impact	1,81	0,67	0,85	16,92	14,54	N	0,34	N	0,98	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13829	13829	T	G	MI.22439	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1493	498	L	R	cTt/cGt	-0,75	0	0	probably_damaging	0,95	neutral	0,36	neutral	0,62	deleterious	-4,17	deleterious	-3,2	medium_impact	3,3	damaging	0,58	neutral	0,45	deleterious	4,33	24	0,09	0,4	disease	0,77	disease	0,89	disease	0,69	disease	0,77	5	neutral	0,95	neutral	0,21	deleterious	1	deleterious	0,86	low_impact	-1,96	medium_impact	0,1	medium_impact	1,81	0,72	0,85	16,92	14,54	N	0,3	N	0,95	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6076	6076	T	A	MI.2244	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	173	58	V	D	gTc/gAc	7,3	1	0	probably_damaging	0,91	deleterious	0	neutral	2,62	deleterious	-4,35	deleterious	-4,39	high_impact	4,92	neutral	0,63	neutral	0,49	deleterious	4,29	24	0,07	0,55	disease	0,92	disease	0,92	disease	0,73	disease	0,84	7	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,85	low_impact	-1,7	low_impact	-1,48	high_impact	3,44	0,63	0,9	1,75	6,95	P	0,7	P	0,83	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13829	13829	T	A	MI.22440	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1493	498	L	H	cTt/cAt	-0,75	0	0	probably_damaging	0,98	neutral	0,53	neutral	0,61	deleterious	-4,74	neutral	-1,92	medium_impact	3,3	neutral	0,69	neutral	0,49	deleterious	4,38	24,1	0,14	0,4	disease	0,82	disease	0,78	disease	0,65	disease	0,75	5	neutral	0,97	neutral	0,28	deleterious	1	deleterious	0,81	low_impact	-2,35	medium_impact	0,26	medium_impact	1,81	0,62	0,8	16,92	14,54	N	0,27	N	0,82	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13831	13831	C	A	MI.22441	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1495	499	L	M	Cta/Ata	-9,69	0	0	probably_damaging	0,97	neutral	0,31	neutral	0,72	neutral	-2,4	neutral	0,11	low_impact	1,73	neutral	0,85	neutral	0,98	deleterious	2,52	19,58	0,35	0,5	disease	0,57	neutral	0,33	neutral	0,29	disease	0,61	2	neutral	0,97	neutral	0,17	neutral	-2	deleterious	0,69	low_impact	-2,18	medium_impact	0,04	medium_impact	0,38	0,78	0,85	22,55	19,69	N	0,52	P	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	C13831A	Thyroid Cancer Cell Line	-	+	Reported	1
chrM	13831	13831	C	G	MI.22442	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1495	499	L	V	Cta/Gta	-9,69	0	0	possibly_damaging	0,61	neutral	0,68	neutral	0,82	neutral	-1,16	neutral	0,09	medium_impact	2,21	neutral	0,83	neutral	0,97	deleterious	2,42	18,92	0,31	0,45	neutral	0,47	neutral	0,36	neutral	0,33	neutral	0,46	1	neutral	0,53	deleterious	0,54	NA	0	deleterious	0,69	medium_impact	-0,93	medium_impact	0,41	medium_impact	0,82	0,77	0,85	22,55	19,69	N	0,35	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13832	13832	T	C	MI.22443	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1496	499	L	P	cTa/cCa	-3,27	0	0	probably_damaging	0,99	neutral	0,28	neutral	0,67	deleterious	-4,54	deleterious	-2,57	medium_impact	3,25	damaging	0,57	neutral	0,37	deleterious	3,96	23,6	0,11	0,4	disease	0,84	disease	0,87	disease	0,69	disease	0,8	6	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,87	low_impact	-2,64	medium_impact	0,01	medium_impact	1,77	0,63	0,8	22,55	19,69	N	0,26	N	0,89	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13832	13832	T	A	MI.22444	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1496	499	L	Q	cTa/cAa	-3,27	0	0	probably_damaging	0,99	neutral	0,3	neutral	0,67	deleterious	-4,13	neutral	-2,05	medium_impact	3,25	neutral	0,73	neutral	0,55	deleterious	4,08	23,7	0,13	0,4	disease	0,74	disease	0,74	disease	0,55	disease	0,71	4	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,79	low_impact	-2,64	medium_impact	0,03	medium_impact	1,77	0,66	0,8	22,55	19,69	N	0,31	N	0,72	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13832	13832	T	G	MI.22445	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1496	499	L	R	cTa/cGa	-3,27	0	0	probably_damaging	0,98	neutral	0,34	neutral	0,68	deleterious	-3,96	neutral	-2,31	medium_impact	3,25	neutral	0,65	neutral	0,43	deleterious	4,19	23,9	0,09	0,35	disease	0,79	disease	0,87	disease	0,67	disease	0,78	6	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,86	low_impact	-2,35	medium_impact	0,07	medium_impact	1,77	0,7	0,85	22,55	19,69	N	0,29	N	0,69	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13834	13834	A	G	MI.22446	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1498	500	T	A	Aca/Gca	-8,08	0	0	benign	0	neutral	0,58	neutral	0,99	neutral	-0,08	neutral	-0,32	low_impact	1,52	neutral	0,85	neutral	0,81	deleterious	0,4	6,59	0,52	0,6	neutral	0,49	neutral	0,31	neutral	0,45	neutral	0,42	2	neutral	0,41	deleterious	0,79	neutral	-6	neutral	0,17	high_impact	2,1	medium_impact	0,31	medium_impact	0,19	0,5	0,8	23,88	19,35	N	0,29	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13834	13834	A	C	MI.22447	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1498	500	T	P	Aca/Cca	-8,08	0	0	benign	0,4	neutral	0,26	neutral	0,91	neutral	-2,74	neutral	-1,96	low_impact	1,86	neutral	0,71	neutral	0,41	deleterious	3,43	23	0,17	0,45	disease	0,7	disease	0,82	disease	0,68	disease	0,79	6	neutral	0,7	neutral	0,43	neutral	-6	deleterious	0,78	medium_impact	-0,58	medium_impact	-0,02	medium_impact	0,5	0,68	0,85	23,88	19,35	N	0,27	N	0,43	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13834	13834	A	T	MI.22448	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1498	500	T	S	Aca/Tca	-8,08	0	0	benign	0,18	neutral	0,47	neutral	0,97	neutral	-0,57	neutral	-1,07	neutral_impact	0,72	neutral	0,88	neutral	0,77	neutral	1,66	14,2	0,53	0,6	neutral	0,48	neutral	0,37	neutral	0,43	neutral	0,44	1	neutral	0,44	deleterious	0,65	neutral	-6	neutral	0,42	medium_impact	-0,12	medium_impact	0,2	medium_impact	-0,55	0,75	0,85	23,88	19,35	N	0,34	N	0,21	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13835	13835	C	T	MI.22449	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1499	500	T	M	aCa/aTa	-5,79	0	0	benign	0,02	neutral	0,35	neutral	1,05	neutral	0,59	neutral	1,99	neutral_impact	-0,18	neutral	0,88	neutral	0,9	deleterious	2,4	18,8	0,3	0,45	disease	0,61	neutral	0,34	neutral	0,32	disease	0,6	2	neutral	0,64	deleterious	0,67	neutral	-6	deleterious	0,66	medium_impact	0,86	medium_impact	0,08	low_impact	-1,37	0,77	0,85	23,88	19,35	N	0,3	N	0,21	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6076	6076	T	G	MI.2245	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	173	58	V	G	gTc/gGc	7,3	1	0	probably_damaging	0,9	deleterious	0	neutral	2,63	deleterious	-3,34	deleterious	-4,45	high_impact	4,92	damaging	0,54	neutral	0,62	deleterious	3,61	23,2	0,09	0,55	disease	0,87	disease	0,88	disease	0,61	disease	0,78	6	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,83	low_impact	-1,65	low_impact	-1,48	high_impact	3,44	0,58	0,9	1,75	6,95	P	0,67	P	0,71	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13835	13835	C	A	MI.22450	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1499	500	T	K	aCa/aAa	-5,79	0	0	benign	0,23	neutral	0,32	neutral	0,92	neutral	-2,12	neutral	-1,45	low_impact	1,86	neutral	0,77	neutral	0,48	deleterious	4,23	23,9	0,19	0,45	disease	0,72	disease	0,72	disease	0,68	disease	0,74	5	neutral	0,61	deleterious	0,55	neutral	-6	deleterious	0,65	medium_impact	-0,25	medium_impact	0,05	medium_impact	0,5	0,72	0,85	23,88	19,35	N	0,24	N	0,45	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13837	13837	G	C	MI.22451	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1501	501	A	P	Gcc/Ccc	-9,23	0	0	probably_damaging	0,99	neutral	0,22	neutral	0,7	deleterious	-4,12	deleterious	-4,49	high_impact	3,75	damaging	0,6	neutral	0,35	deleterious	3,93	23,5	0,09	0,35	disease	0,72	disease	0,92	disease	0,76	disease	0,84	7	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,88	low_impact	-2,64	medium_impact	-0,07	high_impact	2,22	0,81	0,85	3,98	8,04	N	0,37	N	0,93	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13837	13837	G	T	MI.22452	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1501	501	A	S	Gcc/Tcc	-9,23	0	0	possibly_damaging	0,9	neutral	0,62	neutral	0,82	neutral	-1,27	deleterious	-2,69	medium_impact	2,19	neutral	0,64	neutral	0,67	deleterious	3,76	23,4	0,38	0,5	disease	0,56	disease	0,78	disease	0,55	disease	0,54	1	neutral	0,88	neutral	0,36	NA	0	deleterious	0,8	low_impact	-1,65	medium_impact	0,35	medium_impact	0,8	0,89	0,9	3,98	8,04	N	0,26	N	0,51	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13837	13837	G	A	MI.22453	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1501	501	A	T	Gcc/Acc	-9,23	0	0	benign	0,42	neutral	0,53	neutral	0,76	neutral	-2,22	deleterious	-3,59	medium_impact	2,48	damaging	0,59	neutral	0,64	deleterious	4,3	24	0,45	0,55	disease	0,66	disease	0,81	disease	0,58	disease	0,58	2	neutral	0,43	deleterious	0,56	neutral	-3	deleterious	0,81	medium_impact	-0,61	medium_impact	0,26	medium_impact	1,06	0,8	0,85	3,98	8,04	N	0,28	N	0,83	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13838	13838	C	A	MI.22454	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1502	501	A	D	gCc/gAc	3,38	0,99	0	probably_damaging	0,98	neutral	0,21	neutral	0,71	deleterious	-3,43	deleterious	-5,39	high_impact	3,75	neutral	0,62	neutral	0,39	deleterious	4,73	24,6	0,12	0,4	disease	0,81	disease	0,94	disease	0,75	disease	0,88	8	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-2,35	medium_impact	-0,09	high_impact	2,22	0,76	0,85	3,98	8,04	N	0,47	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13838	13838	C	G	MI.22455	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1502	501	A	G	gCc/gGc	3,38	0,99	0	probably_damaging	0,94	neutral	0,41	neutral	1,03	neutral	0,16	deleterious	-3,59	medium_impact	2,37	neutral	0,64	neutral	0,68	deleterious	4,05	23,7	0,23	0,45	disease	0,52	disease	0,8	disease	0,54	disease	0,53	1	neutral	0,94	neutral	0,24	deleterious	1	deleterious	0,77	low_impact	-1,88	medium_impact	0,15	medium_impact	0,96	0,8	0,85	3,98	8,04	N	0,39	N	0,47	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13838	13838	C	T	MI.22456	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1502	501	A	V	gCc/gTc	3,38	0,99	0	possibly_damaging	0,9	neutral	0,59	neutral	0,75	neutral	-2,39	deleterious	-3,59	high_impact	3,75	damaging	0,6	neutral	0,46	deleterious	4,55	24,3	0,37	0,5	disease	0,68	disease	0,85	disease	0,63	disease	0,73	5	neutral	0,88	neutral	0,35	deleterious	1	deleterious	0,82	low_impact	-1,65	medium_impact	0,32	high_impact	2,22	0,87	0,9	3,98	8,04	N	0,49	N	0,89	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13840	13840	C	A	MI.22457	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1504	502	L	M	Cta/Ata	-7,85	0	0	benign	0,22	neutral	0,26	neutral	0,7	neutral	-1,95	neutral	0,95	neutral_impact	0,57	neutral	0,86	neutral	0,98	neutral	1,47	13,14	0,33	0,5	disease	0,66	neutral	0,18	neutral	0,28	neutral	0,36	3	neutral	0,69	deleterious	0,52	neutral	-6	deleterious	0,7	medium_impact	-0,22	medium_impact	-0,02	medium_impact	-0,68	0,76	0,85	18,24	13,14	N	0,43	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13840	13840	C	G	MI.22458	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1504	502	L	V	Cta/Gta	-7,85	0	0	possibly_damaging	0,53	neutral	0,52	neutral	0,73	neutral	-1,59	neutral	-1,18	medium_impact	2,89	neutral	0,74	neutral	0,65	deleterious	3,13	22,6	0,34	0,5	neutral	0,48	neutral	0,46	neutral	0,48	neutral	0,48	0	neutral	0,51	deleterious	0,5	NA	0	deleterious	0,59	medium_impact	-0,8	medium_impact	0,25	medium_impact	1,44	0,66	0,8	18,24	13,14	N	0,33	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13841	13841	T	G	MI.22459	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1505	502	L	R	cTa/cGa	-1,21	0	0	probably_damaging	0,93	neutral	0,35	neutral	0,61	deleterious	-4,33	deleterious	-3,44	medium_impact	3,23	neutral	0,66	neutral	0,34	deleterious	4,22	23,9	0,13	0,4	disease	0,78	disease	0,88	disease	0,69	disease	0,78	6	neutral	0,94	neutral	0,21	deleterious	1	deleterious	0,88	low_impact	-1,81	medium_impact	0,08	medium_impact	1,75	0,71	0,85	18,24	13,14	N	0,27	N	0,98	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6078	6078	A	C	MI.2246	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	175	59	T	P	Aca/Cca	-6,81	0	0	probably_damaging	1	deleterious	0	neutral	2,27	deleterious	-6,46	deleterious	-3,83	high_impact	5,17	neutral	0,62	damaging	0,11	neutral	1,4	12,8	0,13	0,55	disease	0,87	disease	0,79	disease	0,81	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,59	0,9	2,14	7,34	P	0,68	P	0,92	polymorphism	0,95	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13841	13841	T	A	MI.22460	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1505	502	L	Q	cTa/cAa	-1,21	0	0	probably_damaging	0,95	neutral	0,3	neutral	0,6	deleterious	-4,5	deleterious	-2,94	medium_impact	2,89	neutral	0,74	neutral	0,47	deleterious	4,13	23,8	0,16	0,45	disease	0,84	disease	0,79	disease	0,56	disease	0,73	5	neutral	0,96	neutral	0,18	deleterious	1	deleterious	0,84	low_impact	-1,96	medium_impact	0,03	medium_impact	1,44	0,66	0,8	18,24	13,14	N	0,29	N	0,92	polymorphism	0,99	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13841	13841	T	C	MI.22461	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1505	502	L	P	cTa/cCa	-1,21	0	0	probably_damaging	0,95	neutral	0,26	neutral	0,6	deleterious	-4,9	deleterious	-4,23	medium_impact	3,23	damaging	0,56	neutral	0,3	deleterious	3,97	23,6	0,14	0,4	disease	0,8	disease	0,87	disease	0,7	disease	0,8	6	neutral	0,96	neutral	0,16	deleterious	1	deleterious	0,89	low_impact	-1,96	medium_impact	-0,02	medium_impact	1,75	0,61	0,8	18,24	13,14	N	0,26	N	0,95	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13843	13843	G	A	MI.22462	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1507	503	D	N	Gac/Aac	0,17	0,2	0	probably_damaging	0,94	neutral	0,33	neutral	1,01	neutral	0,19	neutral	-2	medium_impact	2,13	neutral	0,74	neutral	0,38	deleterious	4,3	24	0,65	0,7	neutral	0,43	disease	0,7	disease	0,67	disease	0,6	2	neutral	0,94	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-1,88	medium_impact	0,06	medium_impact	0,74	0,83	0,85	15,92	17,99	N	0,28	N	0,47	polymorphism	0,57	0,04	.	.	.	.	.	.	COSM1155543	.	.	.	.	.	.	.	.
chrM	13843	13843	G	C	MI.22463	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1507	503	D	H	Gac/Cac	0,17	0,2	0	probably_damaging	0,98	neutral	0,54	neutral	0,96	neutral	-1,36	neutral	-2,15	medium_impact	2,13	neutral	0,77	neutral	0,35	deleterious	3,71	23,3	0,4	0,5	disease	0,64	disease	0,7	disease	0,75	disease	0,78	6	deleterious	0,98	neutral	0,28	deleterious	1	deleterious	0,74	low_impact	-2,35	medium_impact	0,27	medium_impact	0,74	0,43	0,8	15,92	17,99	N	0,22	N	0,66	disease_causing	0,8	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13843	13843	G	T	MI.22464	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1507	503	D	Y	Gac/Tac	0,17	0,2	0	probably_damaging	0,99	neutral	1	neutral	0,97	neutral	-0,82	deleterious	-3,94	medium_impact	2,34	neutral	0,76	neutral	0,31	deleterious	4	23,6	0,35	0,5	neutral	0,46	disease	0,82	disease	0,74	disease	0,79	6	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,75	low_impact	-2,64	high_impact	1,89	medium_impact	0,94	0,52	0,8	15,92	17,99	N	0,24	N	0,92	disease_causing	0,89	0,08	rs28562381	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13844	13844	A	T	MI.22465	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1508	503	D	V	gAc/gTc	4,06	1	0	probably_damaging	0,98	neutral	0,51	neutral	1,02	neutral	0,46	deleterious	-3,91	medium_impact	2,34	neutral	0,78	neutral	0,34	deleterious	3,81	23,4	0,32	0,5	neutral	0,34	disease	0,74	disease	0,7	disease	0,72	4	neutral	0,98	neutral	0,27	deleterious	1	deleterious	0,7	low_impact	-2,35	medium_impact	0,24	medium_impact	0,94	0,46	0,8	15,92	17,99	N	0,39	N	0,88	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13844	13844	A	C	MI.22466	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1508	503	D	A	gAc/gCc	4,06	1	0	possibly_damaging	0,86	neutral	0,54	neutral	1,01	neutral	0,28	deleterious	-3,01	low_impact	1,88	neutral	0,76	neutral	0,56	deleterious	3,71	23,3	0,33	0,5	neutral	0,35	disease	0,6	disease	0,69	disease	0,52	0	neutral	0,84	neutral	0,34	neutral	-3	deleterious	0,7	low_impact	-1,5	medium_impact	0,27	medium_impact	0,51	0,48	0,8	15,92	17,99	N	0,42	N	0,72	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13844	13844	A	G	MI.22467	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1508	503	D	G	gAc/gGc	4,06	1	0	possibly_damaging	0,89	neutral	0,37	neutral	0,97	neutral	-1,04	deleterious	-3,76	medium_impact	2,34	neutral	0,89	neutral	0,4	deleterious	4,02	23,6	0,35	0,5	neutral	0,3	disease	0,75	disease	0,71	disease	0,75	5	neutral	0,9	neutral	0,24	NA	0	deleterious	0,67	low_impact	-1,61	medium_impact	0,11	medium_impact	0,94	0,39	0,8	15,92	17,99	N	0,53	P	0,8	disease_causing	0,99	0,07	.	.	.	.	.	.	COSM488753	.	.	.	.	.	.	.	.
chrM	13845	13845	C	G	MI.22468	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1509	503	D	E	gaC/gaG	5,44	1	0	benign	0,12	neutral	0,33	neutral	1,22	neutral	2,2	neutral	2,17	neutral_impact	-0,72	neutral	0,79	neutral	0,97	neutral	1,29	12,24	0,57	0,65	neutral	0,26	neutral	0,14	neutral	0,4	neutral	0,22	6	neutral	0,62	deleterious	0,61	neutral	-6	deleterious	0,65	medium_impact	0,08	medium_impact	0,06	low_impact	-1,86	0,71	0,85	15,92	17,99	P	0,57	P	0,08	disease_causing	0,82	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13845	13845	C	A	MI.22469	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1509	503	D	E	gaC/gaA	5,44	1	0	benign	0,12	neutral	0,33	neutral	1,22	neutral	2,2	neutral	2,17	neutral_impact	-0,72	neutral	0,79	neutral	0,97	neutral	1,63	14,01	0,57	0,65	neutral	0,26	neutral	0,14	neutral	0,4	neutral	0,22	6	neutral	0,62	deleterious	0,61	neutral	-6	deleterious	0,65	medium_impact	0,08	medium_impact	0,06	low_impact	-1,86	0,71	0,85	15,92	17,99	P	0,57	P	0,08	disease_causing	0,82	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6078	6078	A	T	MI.2247	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	175	59	T	S	Aca/Tca	-6,81	0	0	probably_damaging	0,98	deleterious	0	neutral	2,25	deleterious	-3,75	deleterious	-2,55	high_impact	3,86	neutral	0,64	damaging	0,16	neutral	1,33	12,41	0,3	0,55	disease	0,61	disease	0,71	disease	0,64	disease	0,62	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,35	low_impact	-1,48	high_impact	2,47	0,66	0,9	2,14	7,34	N	0,32	N	0,79	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13846	13846	C	A	MI.22470	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1510	504	L	I	Ctc/Atc	1,31	0,95	0	probably_damaging	1	neutral	0,56	neutral	0,71	neutral	-1,3	neutral	-1,51	medium_impact	2,02	neutral	0,81	neutral	0,96	deleterious	3,19	22,7	0,37	0,5	neutral	0,44	neutral	0,4	neutral	0,28	neutral	0,45	1	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,29	medium_impact	0,64	0,72	0,85	11,28	15,85	N	0,34	N	0,16	polymorphism	0,8	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13846	13846	C	G	MI.22471	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1510	504	L	V	Ctc/Gtc	1,31	0,95	0	probably_damaging	1	neutral	0,55	neutral	0,6	neutral	-2,29	neutral	-2,39	medium_impact	2,73	neutral	0,8	neutral	0,74	deleterious	3,52	23,1	0,4	0,5	neutral	0,44	disease	0,54	neutral	0,49	neutral	0,48	0	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,28	medium_impact	1,29	0,8	0,85	11,28	15,85	N	0,33	N	0,55	polymorphism	0,69	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13846	13846	C	T	MI.22472	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1510	504	L	F	Ctc/Ttc	1,31	0,95	0	probably_damaging	1	neutral	0,78	neutral	0,6	neutral	-2,32	deleterious	-3,42	medium_impact	2,89	neutral	0,73	damaging	0,27	deleterious	4,04	23,7	0,37	0,5	disease	0,69	disease	0,66	disease	0,53	disease	0,54	1	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,54	medium_impact	1,44	0,68	0,85	11,28	15,85	N	0,28	N	0,84	disease_causing	0,69	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13847	13847	T	G	MI.22473	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1511	504	L	R	cTc/cGc	-0,06	0,87	0,01	probably_damaging	1	neutral	0,36	neutral	0,5	deleterious	-4,67	deleterious	-5,27	high_impact	3,69	neutral	0,61	damaging	0,17	deleterious	4,31	24	0,12	0,4	disease	0,82	disease	0,91	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	0,1	high_impact	2,17	0,68	0,85	11,28	15,85	N	0,35	N	0,98	polymorphism	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13847	13847	T	C	MI.22474	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1511	504	L	P	cTc/cCc	-0,06	0,87	0,01	probably_damaging	1	neutral	0,28	neutral	0,49	deleterious	-5,26	deleterious	-6,09	high_impact	3,69	damaging	0,56	damaging	0,12	deleterious	4,02	23,6	0,12	0,4	disease	0,72	disease	0,87	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,89	low_impact	-3,6	medium_impact	0,01	high_impact	2,17	0,57	0,8	11,28	15,85	N	0,34	N	0,94	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13847	13847	T	A	MI.22475	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1511	504	L	H	cTc/cAc	-0,06	0,87	0,01	probably_damaging	1	neutral	0,54	neutral	0,49	deleterious	-5,22	deleterious	-6,09	high_impact	3,69	neutral	0,66	damaging	0,18	deleterious	4,24	23,9	0,16	0,45	disease	0,79	disease	0,83	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,27	high_impact	2,17	0,62	0,8	11,28	15,85	N	0,3	N	0,87	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13849	13849	A	C	MI.22476	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1513	505	N	H	Aac/Cac	-13,12	0	0	benign	0,02	neutral	0,53	neutral	0,91	neutral	-2,33	deleterious	-3,41	medium_impact	2,28	neutral	0,79	neutral	0,74	deleterious	0,04	2,98	0,54	0,6	disease	0,78	neutral	0,39	disease	0,51	disease	0,66	3	neutral	0,45	deleterious	0,76	neutral	-3	neutral	0,23	medium_impact	0,86	medium_impact	0,26	medium_impact	0,88	0,39	0,8	20,23	16,88	N	0,32	N	0,5	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	A13849C	MELAS	+	-	Reported-possible secondary	1
chrM	13849	13849	A	G	MI.22477	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1513	505	N	D	Aac/Gac	-13,12	0	0	benign	0,23	neutral	0,25	neutral	0,92	neutral	-1,81	deleterious	-3,25	medium_impact	2,28	neutral	0,77	neutral	0,66	neutral	1,28	12,18	0,7	0,75	disease	0,71	neutral	0,45	disease	0,59	disease	0,67	3	neutral	0,7	deleterious	0,51	neutral	-3	deleterious	0,6	medium_impact	-0,25	medium_impact	-0,03	medium_impact	0,88	0,45	0,8	20,23	16,88	N	0,35	N	0,64	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13849	13849	A	T	MI.22478	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1513	505	N	Y	Aac/Tac	-13,12	0	0	benign	0,01	neutral	1	neutral	0,93	neutral	-1,43	deleterious	-5,28	low_impact	1,04	neutral	0,82	neutral	0,63	deleterious	0,46	7,13	0,39	0,5	neutral	0,44	neutral	0,48	neutral	0,32	neutral	0,49	0	neutral	0,01	deleterious	1	neutral	-6	neutral	0,19	medium_impact	1,15	high_impact	1,89	medium_impact	-0,25	0,31	0,8	20,23	16,88	N	0,25	N	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13850	13850	A	T	MI.22479	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1514	505	N	I	aAc/aTc	0,86	0	0	benign	0	neutral	0,49	neutral	0,96	neutral	-0,59	deleterious	-5,63	low_impact	0,81	neutral	0,88	neutral	0,85	deleterious	2,65	20,5	0,35	0,5	disease	0,62	neutral	0,46	neutral	0,26	disease	0,61	2	neutral	0,5	deleterious	0,75	neutral	-6	deleterious	0,64	high_impact	2,1	medium_impact	0,22	medium_impact	-0,46	0,3	0,8	20,23	16,88	N	0,37	N	0,86	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6078	6078	A	G	MI.2248	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	175	59	T	A	Aca/Gca	-6,81	0	0	probably_damaging	0,98	deleterious	0	neutral	2,2	deleterious	-4,2	deleterious	-3,19	high_impact	5,17	neutral	0,81	damaging	0,14	neutral	1,55	13,56	0,28	0,55	neutral	0,35	disease	0,64	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,71	low_impact	-2,35	low_impact	-1,48	high_impact	3,68	0,53	0,9	2,14	7,34	N	0,49	N	0,69	polymorphism	0,99	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13850	13850	A	C	MI.22480	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1514	505	N	T	aAc/aCc	0,86	0	0	benign	0,01	neutral	0,44	neutral	1	neutral	0,06	deleterious	-3,54	neutral_impact	0,29	neutral	0,87	neutral	0,9	neutral	1,59	13,81	0,58	0,65	disease	0,57	neutral	0,23	neutral	0,21	disease	0,54	1	neutral	0,55	deleterious	0,72	neutral	-6	deleterious	0,56	medium_impact	1,15	medium_impact	0,18	medium_impact	-0,94	0,45	0,8	20,23	16,88	N	0,37	N	0,14	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13850	13850	A	G	MI.22481	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1514	505	N	S	aAc/aGc	0,86	0	0	benign	0,01	neutral	0,51	neutral	1,15	neutral	1,33	deleterious	-2,62	neutral_impact	-0,3	neutral	0,88	neutral	0,99	deleterious	-0,06	2,01	0,7	0,75	neutral	0,31	neutral	0,15	neutral	0,24	neutral	0,29	4	neutral	0,48	deleterious	0,75	neutral	-6	deleterious	0,45	medium_impact	1,15	medium_impact	0,24	low_impact	-1,48	0,21	0,8	20,23	16,88	N	0,43	N	0,11	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13851	13851	C	A	MI.22482	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1515	505	N	K	aaC/aaA	-0,06	0	0	benign	0,18	neutral	0,34	neutral	0,95	neutral	-0,9	deleterious	-3,91	low_impact	1,73	neutral	0,76	neutral	0,63	deleterious	1,88	15,44	0,66	0,7	disease	0,53	disease	0,54	disease	0,51	disease	0,51	0	neutral	0,6	deleterious	0,58	neutral	-6	deleterious	0,59	medium_impact	-0,12	medium_impact	0,07	medium_impact	0,38	0,43	0,8	20,23	16,88	N	0,35	N	0,72	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13851	13851	C	G	MI.22483	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1515	505	N	K	aaC/aaG	-0,06	0	0	benign	0,18	neutral	0,34	neutral	0,95	neutral	-0,9	deleterious	-3,91	low_impact	1,73	neutral	0,76	neutral	0,63	neutral	1,44	12,98	0,66	0,7	disease	0,53	disease	0,54	disease	0,51	disease	0,51	0	neutral	0,6	deleterious	0,58	neutral	-6	deleterious	0,59	medium_impact	-0,12	medium_impact	0,07	medium_impact	0,38	0,43	0,8	20,23	16,88	N	0,35	N	0,72	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13852	13852	T	A	MI.22484	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1516	506	Y	N	Tac/Aac	-3,5	0	0	benign	0,26	neutral	0,35	neutral	1,13	neutral	2,24	neutral	2,34	neutral_impact	-0,48	neutral	0,82	neutral	0,99	deleterious	1,99	16,16	0,47	0,55	neutral	0,25	neutral	0,27	neutral	0,2	neutral	0,43	1	neutral	0,58	deleterious	0,55	neutral	-6	deleterious	0,62	medium_impact	-0,32	medium_impact	0,08	low_impact	-1,64	0,39	0,8	27,53	15,58	N	0,36	N	0,13	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13852	13852	T	C	MI.22485	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1516	506	Y	H	Tac/Cac	-3,5	0	0	possibly_damaging	0,84	neutral	0,54	neutral	1	neutral	-0,11	neutral	0,59	neutral_impact	0,24	neutral	0,83	neutral	0,92	deleterious	1,84	15,2	0,65	0,7	neutral	0,43	neutral	0,31	neutral	0,25	neutral	0,48	1	neutral	0,82	neutral	0,35	neutral	-3	deleterious	0,65	low_impact	-1,43	medium_impact	0,27	medium_impact	-0,98	0,35	0,8	27,53	15,58	N	0,26	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13852	13852	T	G	MI.22486	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1516	506	Y	D	Tac/Gac	-3,5	0	0	benign	0,33	neutral	0,21	neutral	1,03	neutral	0,96	neutral	0,4	low_impact	1,28	neutral	0,78	neutral	0,72	deleterious	2,66	20,6	0,39	0,5	neutral	0,42	disease	0,63	neutral	0,43	neutral	0,5	0	neutral	0,75	neutral	0,44	neutral	-6	deleterious	0,69	medium_impact	-0,45	medium_impact	-0,09	medium_impact	-0,03	0,51	0,8	27,53	15,58	N	0,32	N	0,68	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13853	13853	A	T	MI.22487	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1517	506	Y	F	tAc/tTc	-1,89	0	0	benign	0	neutral	0,72	neutral	0,98	neutral	-1,09	neutral	-0,38	neutral_impact	-0,3	neutral	0,84	neutral	0,87	deleterious	0,25	5,2	0,55	0,6	disease	0,64	neutral	0,28	neutral	0,32	disease	0,56	1	neutral	0,27	deleterious	0,86	neutral	-6	deleterious	0,48	high_impact	2,1	medium_impact	0,46	low_impact	-1,48	0,37	0,8	27,53	15,58	N	0,29	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13853	13853	A	C	MI.22488	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1517	506	Y	S	tAc/tCc	-1,89	0	0	benign	0,01	neutral	0,49	neutral	1,12	neutral	2,19	neutral	1,61	neutral_impact	-1,38	neutral	0,85	neutral	0,95	neutral	1,62	13,95	0,32	0,5	neutral	0,31	neutral	0,15	neutral	0,19	neutral	0,24	5	neutral	0,5	deleterious	0,74	neutral	-6	deleterious	0,57	medium_impact	1,15	medium_impact	0,22	low_impact	-2,46	0,33	0,8	27,53	15,58	N	0,4	N	0,2	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13853	13853	A	G	MI.22489	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1517	506	Y	C	tAc/tGc	-1,89	0	0	possibly_damaging	0,84	neutral	0,17	neutral	0,97	neutral	-2,16	neutral	-0,67	low_impact	0,94	neutral	0,73	neutral	0,48	deleterious	2,86	21,7	0,33	0,5	disease	0,79	disease	0,59	neutral	0,29	disease	0,53	1	neutral	0,92	neutral	0,17	neutral	-3	deleterious	0,72	low_impact	-1,43	medium_impact	-0,15	medium_impact	-0,34	0,13	0,8	27,53	15,58	N	0,38	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6079	6079	C	A	MI.2249	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	176	59	T	K	aCa/aAa	6,83	1	0	probably_damaging	1	deleterious	0	neutral	2,15	deleterious	-5,39	deleterious	-3,83	high_impact	5,17	neutral	0,66	damaging	0,09	deleterious	4,27	23,9	0,12	0,55	disease	0,87	disease	0,88	disease	0,8	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,7	0,9	2,14	7,34	P	0,74	P	0,88	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13855	13855	C	G	MI.22490	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1519	507	L	V	Cta/Gta	-8,77	0	0	possibly_damaging	0,54	neutral	0,53	neutral	0,91	neutral	-0,6	neutral	-1,21	medium_impact	2,4	neutral	0,85	neutral	0,91	deleterious	3,49	23,1	0,57	0,65	neutral	0,46	neutral	0,34	disease	0,57	neutral	0,5	0	neutral	0,51	deleterious	0,5	NA	0	deleterious	0,7	medium_impact	-0,81	medium_impact	0,26	medium_impact	0,99	0,57	0,8	21,89	14,38	N	0,34	N	0,23	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13855	13855	C	A	MI.22491	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1519	507	L	M	Cta/Ata	-8,77	0	0	benign	0,15	neutral	0,25	neutral	0,89	neutral	-0,75	neutral	0,33	neutral_impact	0,48	neutral	0,87	neutral	0,99	deleterious	2,21	17,55	0,37	0,5	disease	0,62	neutral	0,12	neutral	0,23	neutral	0,39	2	neutral	0,71	deleterious	0,55	neutral	-6	deleterious	0,69	medium_impact	-0,03	medium_impact	-0,03	medium_impact	-0,76	0,68	0,85	21,89	14,38	N	0,5	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13856	13856	T	G	MI.22492	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1520	507	L	R	cTa/cGa	-2,58	0	0	probably_damaging	0,91	neutral	0,37	neutral	0,75	deleterious	-3,4	deleterious	-3,42	medium_impact	2,25	neutral	0,73	neutral	0,6	deleterious	4,31	24	0,28	0,45	disease	0,71	disease	0,82	disease	0,72	disease	0,78	6	neutral	0,91	neutral	0,23	deleterious	1	deleterious	0,85	low_impact	-1,7	medium_impact	0,11	medium_impact	0,85	0,6	0,8	21,89	14,38	N	0,25	N	0,65	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13856	13856	T	A	MI.22493	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1520	507	L	Q	cTa/cAa	-2,58	0	0	probably_damaging	0,93	neutral	0,32	neutral	0,75	deleterious	-3,49	deleterious	-3,01	low_impact	1,85	neutral	0,81	neutral	0,79	deleterious	4,26	23,9	0,25	0,45	disease	0,79	disease	0,69	neutral	0,36	disease	0,6	2	neutral	0,94	neutral	0,2	neutral	-2	deleterious	0,81	low_impact	-1,81	medium_impact	0,05	medium_impact	0,49	0,52	0,8	21,89	14,38	N	0,29	N	0,59	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13856	13856	T	C	MI.22494	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1520	507	L	P	cTa/cCa	-2,58	0	0	probably_damaging	0,93	neutral	0,23	neutral	0,74	deleterious	-4,12	deleterious	-4,15	medium_impact	2,15	neutral	0,64	neutral	0,57	deleterious	4,06	23,7	0,16	0,45	disease	0,64	disease	0,83	disease	0,73	disease	0,79	6	neutral	0,95	neutral	0,15	deleterious	1	deleterious	0,85	low_impact	-1,81	medium_impact	-0,06	medium_impact	0,76	0,4	0,8	21,89	14,38	N	0,27	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13858	13858	A	T	MI.22495	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1522	508	T	S	Acc/Tcc	-3,5	0	0	possibly_damaging	0,64	neutral	0,52	neutral	1,01	neutral	0,06	neutral	-1,71	low_impact	1,49	neutral	0,79	neutral	0,98	deleterious	0,56	7,89	0,57	0,65	neutral	0,42	neutral	0,4	neutral	0,31	neutral	0,45	1	neutral	0,61	neutral	0,44	neutral	-3	neutral	0,39	medium_impact	-0,98	medium_impact	0,25	medium_impact	0,16	0,41	0,8	5,64	13,54	N	0,34	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13858	13858	A	G	MI.22496	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1522	508	T	A	Acc/Gcc	-3,5	0	0	benign	0,05	neutral	0,58	neutral	0,91	neutral	-0,76	deleterious	-2,84	low_impact	1,9	neutral	0,84	neutral	0,98	deleterious	0,59	8,12	0,72	0,75	neutral	0,38	neutral	0,33	neutral	0,36	neutral	0,43	1	neutral	0,36	deleterious	0,77	neutral	-6	neutral	0,18	medium_impact	0,47	medium_impact	0,31	medium_impact	0,53	0,33	0,8	5,64	13,54	N	0,35	N	0,03	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13858	13858	A	C	MI.22497	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1522	508	T	P	Acc/Ccc	-3,5	0	0	probably_damaging	0,93	neutral	0,25	neutral	0,8	deleterious	-3,33	deleterious	-4,08	medium_impact	2,48	neutral	0,66	neutral	0,63	deleterious	3,3	22,9	0,21	0,45	disease	0,77	disease	0,82	disease	0,74	disease	0,77	5	neutral	0,95	neutral	0,16	deleterious	1	deleterious	0,72	low_impact	-1,81	medium_impact	-0,03	medium_impact	1,06	0,52	0,8	5,64	13,54	N	0,3	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13859	13859	C	A	MI.22498	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1523	508	T	N	aCc/aAc	-0,06	0	0	probably_damaging	0,93	neutral	0,38	neutral	0,88	neutral	-1,26	deleterious	-3,02	medium_impact	2,3	neutral	0,74	neutral	0,79	deleterious	3,65	23,2	0,56	0,6	disease	0,6	disease	0,71	neutral	0,49	disease	0,55	1	neutral	0,93	neutral	0,23	deleterious	1	deleterious	0,66	low_impact	-1,81	medium_impact	0,12	medium_impact	0,9	0,69	0,85	5,64	13,54	N	0,3	N	0,59	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13859	13859	C	G	MI.22499	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1523	508	T	S	aCc/aGc	-0,06	0	0	possibly_damaging	0,64	neutral	0,52	neutral	1,01	neutral	0,06	neutral	-1,71	low_impact	1,49	neutral	0,79	neutral	0,98	deleterious	0,75	9,13	0,57	0,65	neutral	0,42	neutral	0,4	neutral	0,31	neutral	0,45	1	neutral	0,61	neutral	0,44	neutral	-3	neutral	0,39	medium_impact	-0,98	medium_impact	0,25	medium_impact	0,16	0,41	0,8	5,64	13,54	N	0,34	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8632	8632	T	A	MI.225	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	106	36	Y	N	Tat/Aat	-10,05	0	0	benign	0,08	neutral	0,33	neutral	4,48	neutral	2,41	neutral	0,33	neutral_impact	-0,96	neutral	0,89	neutral	0,83	neutral	1,19	11,71	0,52	0,65	neutral	0,27	disease	0,53	neutral	0,28	neutral	0,47	1	neutral	0,63	deleterious	0,63	neutral	-6	neutral	0,19	medium_impact	0,25	medium_impact	0,12	low_impact	-1,92	0,37	0,9	29,2	23,72	N	0,35	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6079	6079	C	T	MI.2250	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	176	59	T	M	aCa/aTa	6,83	1	0	probably_damaging	1	deleterious	0	neutral	2,19	deleterious	-6,67	deleterious	-3,83	high_impact	4,62	neutral	0,76	damaging	0,11	deleterious	3,91	23,5	0,21	0,55	disease	0,91	disease	0,78	disease	0,68	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,17	0,74	0,9	2,14	7,34	P	0,54	P	0,96	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13859	13859	C	T	MI.22500	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1523	508	T	I	aCc/aTc	-0,06	0	0	possibly_damaging	0,87	neutral	0,43	neutral	0,84	neutral	-1,95	deleterious	-4,33	medium_impact	2,64	neutral	0,72	neutral	0,62	deleterious	3,65	23,2	0,45	0,55	disease	0,77	disease	0,69	disease	0,59	disease	0,63	3	neutral	0,87	neutral	0,28	NA	0	deleterious	0,63	low_impact	-1,53	medium_impact	0,17	medium_impact	1,21	0,58	0,8	5,64	13,54	N	0,28	N	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13861	13861	A	C	MI.22501	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1525	509	N	H	Aac/Cac	-12,44	0	0	probably_damaging	0,96	neutral	0,59	neutral	0,91	neutral	-1,61	neutral	0,9	low_impact	1,55	neutral	0,83	neutral	0,99	deleterious	1,83	15,18	0,81	0,85	neutral	0,44	neutral	0,24	neutral	0,27	neutral	0,45	1	neutral	0,96	neutral	0,32	neutral	-2	deleterious	0,62	low_impact	-2,06	medium_impact	0,32	medium_impact	0,21	0,52	0,8	23,71	22,53	N	0,33	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13861	13861	A	T	MI.22502	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1525	509	N	Y	Aac/Tac	-12,44	0	0	probably_damaging	0,96	neutral	1	neutral	0,96	neutral	-0,43	neutral	1,33	medium_impact	2,41	neutral	0,85	neutral	0,96	deleterious	2,39	18,75	0,49	0,55	neutral	0,32	neutral	0,45	neutral	0,29	neutral	0,47	1	neutral	0,96	deleterious	0,52	deleterious	1	deleterious	0,66	low_impact	-2,06	high_impact	1,89	medium_impact	1	0,42	0,8	23,71	22,53	N	0,24	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13861	13861	A	G	MI.22503	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1525	509	N	D	Aac/Gac	-12,44	0	0	possibly_damaging	0,64	neutral	0,53	neutral	0,89	neutral	-2,32	neutral	-1,26	medium_impact	2,52	neutral	0,74	neutral	0,75	deleterious	2,29	18,1	0,82	0,85	neutral	0,34	neutral	0,41	neutral	0,43	neutral	0,47	1	neutral	0,6	neutral	0,45	NA	0	deleterious	0,44	medium_impact	-0,98	medium_impact	0,26	medium_impact	1,1	0,48	0,8	23,71	22,53	N	0,36	N	0,39	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13862	13862	A	C	MI.22504	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1526	509	N	T	aAc/aCc	-5,1	0	0	possibly_damaging	0,64	neutral	0,7	neutral	0,99	neutral	-0,06	neutral	-0,39	low_impact	1,49	neutral	0,85	neutral	0,88	deleterious	0,59	8,07	0,69	0,75	neutral	0,37	neutral	0,23	neutral	0,19	neutral	0,44	1	neutral	0,56	deleterious	0,53	neutral	-3	neutral	0,38	medium_impact	-0,98	medium_impact	0,44	medium_impact	0,16	0,44	0,8	23,71	22,53	N	0,36	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13862	13862	A	G	MI.22505	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1526	509	N	S	aAc/aGc	-5,1	0	0	benign	0,13	neutral	0,79	neutral	0,98	neutral	-0,25	neutral	-0,28	low_impact	1,75	neutral	0,82	neutral	0,91	neutral	-0,57	0,15	0,8	0,85	neutral	0,31	neutral	0,13	neutral	0,21	neutral	0,28	4	neutral	0,1	deleterious	0,83	neutral	-6	neutral	0,11	medium_impact	0,04	medium_impact	0,55	medium_impact	0,4	0,2	0,8	23,71	22,53	N	0,35	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13862	13862	A	T	MI.22506	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1526	509	N	I	aAc/aTc	-5,1	0	0	probably_damaging	0,93	neutral	0,49	neutral	0,95	neutral	-0,63	neutral	-0,59	medium_impact	2,32	neutral	0,85	neutral	0,66	deleterious	3,95	23,6	0,45	0,55	disease	0,56	neutral	0,48	neutral	0,39	disease	0,61	2	neutral	0,92	neutral	0,28	deleterious	1	deleterious	0,64	low_impact	-1,81	medium_impact	0,22	medium_impact	0,92	0,34	0,8	23,71	22,53	N	0,3	N	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13863	13863	C	A	MI.22507	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1527	509	N	K	aaC/aaA	-0,75	0	0	possibly_damaging	0,75	neutral	0,78	neutral	0,92	neutral	-1,27	neutral	-0,21	medium_impact	2,06	neutral	0,86	neutral	0,91	neutral	1,57	13,71	0,67	0,7	neutral	0,28	neutral	0,46	neutral	0,44	neutral	0,46	1	neutral	0,7	deleterious	0,52	NA	0	deleterious	0,45	low_impact	-1,2	medium_impact	0,54	medium_impact	0,68	0,43	0,8	23,71	22,53	N	0,24	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13863	13863	C	G	MI.22508	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1527	509	N	K	aaC/aaG	-0,75	0	0	possibly_damaging	0,75	neutral	0,78	neutral	0,92	neutral	-1,27	neutral	-0,21	medium_impact	2,06	neutral	0,86	neutral	0,91	neutral	1,09	11,17	0,67	0,7	neutral	0,28	neutral	0,46	neutral	0,44	neutral	0,46	1	neutral	0,7	deleterious	0,52	NA	0	deleterious	0,45	low_impact	-1,2	medium_impact	0,54	medium_impact	0,68	0,43	0,8	23,71	22,53	N	0,24	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13864	13864	A	C	MI.22509	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1528	510	K	Q	Aaa/Caa	-9,23	0	0	possibly_damaging	0,82	neutral	0,34	neutral	0,82	neutral	-1,69	neutral	0,06	medium_impact	2,04	neutral	0,8	neutral	0,82	deleterious	2,15	17,21	0,54	0,6	neutral	0,48	disease	0,55	neutral	0,49	neutral	0,49	0	neutral	0,84	neutral	0,26	NA	0	deleterious	0,71	low_impact	-1,37	medium_impact	0,07	medium_impact	0,66	0,72	0,85	15,59	12,75	N	0,36	N	0,71	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6081	6081	G	A	MI.2251	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	178	60	A	T	Gcc/Acc	-7,28	0	0	benign	0,41	deleterious	0	neutral	2,72	neutral	-1,14	neutral	-2,17	medium_impact	2,75	damaging	0,48	neutral	0,48	deleterious	4,05	23,7	0,28	0,55	neutral	0,38	disease	0,85	neutral	0,47	disease	0,66	3	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,57	medium_impact	-0,61	low_impact	-1,48	medium_impact	1,44	0,67	0,9	6,63	22,87	P	0,5	N	0,2	polymorphism	0,94	0,09	.	.	.	.	.	.	.	.	0,15	G6081A	Prostate Cancer	+	-	Reported	1
chrM	13864	13864	A	G	MI.22510	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1528	510	K	E	Aaa/Gaa	-9,23	0	0	possibly_damaging	0,54	neutral	0,35	neutral	0,84	neutral	-1,39	neutral	-0,07	medium_impact	2,84	neutral	0,77	neutral	0,69	deleterious	3,81	23,4	0,5	0,6	neutral	0,42	disease	0,72	disease	0,53	disease	0,61	2	neutral	0,64	neutral	0,41	NA	0	deleterious	0,74	medium_impact	-0,81	medium_impact	0,08	medium_impact	1,39	0,82	0,85	15,59	12,75	N	0,35	N	0,68	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13865	13865	A	C	MI.22511	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1529	510	K	T	aAa/aCa	-0,06	0	0	possibly_damaging	0,45	neutral	0,47	neutral	0,83	neutral	-1,6	neutral	0,25	low_impact	1,68	neutral	0,85	neutral	0,96	deleterious	2,7	20,8	0,45	0,55	disease	0,51	neutral	0,47	neutral	0,34	neutral	0,43	1	neutral	0,49	deleterious	0,51	neutral	-3	deleterious	0,72	medium_impact	-0,66	medium_impact	0,2	medium_impact	0,33	0,68	0,85	15,59	12,75	N	0,37	N	0,57	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13865	13865	A	T	MI.22512	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1529	510	K	M	aAa/aTa	-0,06	0	0	probably_damaging	0,97	neutral	0,25	neutral	0,77	deleterious	-3,22	neutral	-1,18	medium_impact	2,84	neutral	0,78	neutral	0,67	deleterious	4,11	23,7	0,34	0,5	disease	0,75	disease	0,61	neutral	0,5	disease	0,51	0	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,75	low_impact	-2,18	medium_impact	-0,03	medium_impact	1,39	0,44	0,8	15,59	12,75	N	0,34	N	0,79	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13866	13866	A	T	MI.22513	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1530	510	K	N	aaA/aaT	0,4	0	0	benign	0,02	neutral	0,37	neutral	0,87	neutral	-1,04	neutral	3,27	low_impact	1,02	neutral	0,88	neutral	0,97	neutral	1,8	14,97	0,63	0,65	neutral	0,35	neutral	0,38	neutral	0,32	neutral	0,46	1	neutral	0,61	deleterious	0,68	neutral	-6	deleterious	0,7	medium_impact	0,86	medium_impact	0,11	medium_impact	-0,27	0,86	0,9	15,59	12,75	N	0,35	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13866	13866	A	C	MI.22514	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1530	510	K	N	aaA/aaC	0,4	0	0	benign	0,02	neutral	0,37	neutral	0,87	neutral	-1,04	neutral	3,27	low_impact	1,02	neutral	0,88	neutral	0,97	neutral	1,74	14,61	0,63	0,65	neutral	0,35	neutral	0,38	neutral	0,32	neutral	0,46	1	neutral	0,61	deleterious	0,68	neutral	-6	deleterious	0,7	medium_impact	0,86	medium_impact	0,11	medium_impact	-0,27	0,86	0,9	15,59	12,75	N	0,35	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13867	13867	C	G	MI.22515	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1531	511	L	V	Ctt/Gtt	-4,42	0	0	benign	0,09	neutral	0,53	neutral	0,93	neutral	-0,91	neutral	-2,38	medium_impact	2,63	neutral	0,81	neutral	0,79	deleterious	2,48	19,33	0,61	0,65	disease	0,64	neutral	0,33	neutral	0,4	disease	0,63	3	neutral	0,39	deleterious	0,72	neutral	-3	deleterious	0,75	medium_impact	0,21	medium_impact	0,26	medium_impact	1,2	0,77	0,85	13,43	14,65	N	0,3	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13867	13867	C	T	MI.22516	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1531	511	L	F	Ctt/Ttt	-4,42	0	0	possibly_damaging	0,88	neutral	0,7	neutral	0,97	neutral	-0,32	deleterious	-3,05	low_impact	1,74	neutral	0,85	neutral	0,82	deleterious	2,81	21,4	0,62	0,65	disease	0,59	neutral	0,31	neutral	0,25	disease	0,62	2	neutral	0,86	neutral	0,41	neutral	-3	deleterious	0,75	low_impact	-1,57	medium_impact	0,44	medium_impact	0,39	0,65	0,8	13,43	14,65	N	0,25	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13867	13867	C	A	MI.22517	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1531	511	L	I	Ctt/Att	-4,42	0	0	benign	0,14	neutral	0,42	neutral	0,96	neutral	-0,43	neutral	-1,59	medium_impact	2,38	neutral	0,76	neutral	0,75	deleterious	3,33	22,9	0,51	0,6	disease	0,64	neutral	0,29	neutral	0,25	disease	0,58	2	neutral	0,51	deleterious	0,64	neutral	-3	deleterious	0,74	medium_impact	0	medium_impact	0,16	medium_impact	0,97	0,76	0,85	13,43	14,65	N	0,38	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13868	13868	T	A	MI.22518	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1532	511	L	H	cTt/cAt	-1,44	0	0	probably_damaging	0,98	neutral	0,56	neutral	0,87	neutral	-2,44	deleterious	-5,6	medium_impact	2,63	neutral	0,82	neutral	0,58	deleterious	4,38	24,1	0,32	0,5	disease	0,57	disease	0,63	neutral	0,33	disease	0,53	1	neutral	0,97	neutral	0,29	deleterious	1	deleterious	0,79	low_impact	-2,35	medium_impact	0,29	medium_impact	1,2	0,6	0,8	13,43	14,65	N	0,23	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13868	13868	T	G	MI.22519	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1532	511	L	R	cTt/cGt	-1,44	0	0	probably_damaging	0,93	neutral	0,37	neutral	0,88	neutral	-1,98	deleterious	-4,95	medium_impact	3,18	neutral	0,78	neutral	0,6	deleterious	4,32	24	0,36	0,5	disease	0,71	disease	0,81	disease	0,54	disease	0,75	5	neutral	0,94	neutral	0,22	deleterious	1	deleterious	0,86	low_impact	-1,81	medium_impact	0,11	medium_impact	1,7	0,55	0,8	13,43	14,65	N	0,29	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6081	6081	G	C	MI.2252	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	178	60	A	P	Gcc/Ccc	-7,28	0	0	possibly_damaging	0,83	deleterious	0	neutral	2,65	deleterious	-3,57	deleterious	-2,9	high_impact	4,59	damaging	0,59	neutral	0,43	deleterious	3,71	23,3	0,09	0,55	disease	0,76	disease	0,9	disease	0,68	disease	0,76	5	deleterious	1	neutral	0,09	deleterious	5	deleterious	0,85	low_impact	-1,4	low_impact	-1,48	high_impact	3,14	0,87	0,9	6,63	22,87	N	0,5	N	0,85	polymorphism	0,81	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13868	13868	T	C	MI.22520	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1532	511	L	P	cTt/cCt	-1,44	0	0	probably_damaging	0,95	neutral	0,23	neutral	0,88	neutral	-2,28	deleterious	-5,56	medium_impact	2,63	neutral	0,68	neutral	0,64	deleterious	4,05	23,7	0,42	0,55	disease	0,68	disease	0,79	neutral	0,35	disease	0,59	2	neutral	0,96	neutral	0,14	deleterious	1	deleterious	0,86	low_impact	-1,96	medium_impact	-0,06	medium_impact	1,2	0,59	0,8	13,43	14,65	N	0,33	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13870	13870	A	C	MI.22521	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1534	512	K	Q	Aaa/Caa	-3,04	0	0	probably_damaging	0,94	neutral	0,32	neutral	0,91	neutral	-0,96	neutral	-2,4	low_impact	1,81	neutral	0,86	neutral	0,45	deleterious	2,51	19,53	0,59	0,65	neutral	0,5	neutral	0,49	neutral	0,29	neutral	0,43	1	neutral	0,95	neutral	0,19	neutral	-2	deleterious	0,74	low_impact	-1,88	medium_impact	0,05	medium_impact	0,45	0,86	0,9	25,7	17,84	N	0,3	N	0,71	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13870	13870	A	G	MI.22522	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1534	512	K	E	Aaa/Gaa	-3,04	0	0	benign	0,3	neutral	0,32	neutral	0,93	neutral	-0,51	deleterious	-2,66	low_impact	1,66	neutral	0,79	damaging	0,26	deleterious	4,1	23,7	0,44	0,55	neutral	0,48	disease	0,65	neutral	0,48	disease	0,52	0	neutral	0,61	deleterious	0,51	neutral	-6	deleterious	0,76	medium_impact	-0,4	medium_impact	0,05	medium_impact	0,31	0,8	0,85	25,7	17,84	N	0,25	N	0,76	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13871	13871	A	T	MI.22523	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1535	512	K	M	aAa/aTa	2,69	0,08	0	probably_damaging	1	neutral	0,23	neutral	0,9	neutral	-2,51	deleterious	-4,11	medium_impact	2,02	neutral	0,84	neutral	0,9	deleterious	4,06	23,7	0,32	0,5	disease	0,72	neutral	0,47	neutral	0,3	disease	0,62	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,06	medium_impact	0,64	0,58	0,8	25,7	17,84	N	0,46	N	0,77	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13871	13871	A	C	MI.22524	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1535	512	K	T	aAa/aCa	2,69	0,08	0	probably_damaging	0,97	neutral	0,42	neutral	0,97	neutral	-0,94	deleterious	-3,83	neutral_impact	0,28	neutral	0,83	neutral	0,92	deleterious	2,6	20,2	0,38	0,5	neutral	0,48	neutral	0,37	neutral	0,28	neutral	0,44	1	neutral	0,97	neutral	0,23	neutral	-2	deleterious	0,72	low_impact	-2,18	medium_impact	0,16	medium_impact	-0,95	0,84	0,9	25,7	17,84	N	0,35	N	0,8	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13872	13872	A	C	MI.22525	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1536	512	K	N	aaA/aaC	-0,06	0	0	probably_damaging	0,98	neutral	0,34	neutral	0,95	neutral	-1,22	deleterious	-3,13	low_impact	1,47	neutral	0,81	neutral	0,39	deleterious	2,91	21,9	0,62	0,65	disease	0,59	disease	0,54	neutral	0,31	disease	0,51	0	deleterious	0,98	neutral	0,18	neutral	-2	deleterious	0,77	low_impact	-2,35	medium_impact	0,07	medium_impact	0,14	0,94	0,95	25,7	17,84	N	0,29	N	0,56	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13872	13872	A	T	MI.22526	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1536	512	K	N	aaA/aaT	-0,06	0	0	probably_damaging	0,98	neutral	0,34	neutral	0,95	neutral	-1,22	deleterious	-3,13	low_impact	1,47	neutral	0,81	neutral	0,39	deleterious	2,97	22,1	0,62	0,65	disease	0,59	disease	0,54	neutral	0,31	disease	0,51	0	deleterious	0,98	neutral	0,18	neutral	-2	deleterious	0,77	low_impact	-2,35	medium_impact	0,07	medium_impact	0,14	0,94	0,95	25,7	17,84	N	0,29	N	0,56	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13873	13873	A	G	MI.22527	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1537	513	M	V	Ata/Gta	-0,29	0	0	benign	0	neutral	0,51	neutral	1,02	neutral	0,63	neutral	-0,79	low_impact	1,5	neutral	0,8	neutral	0,78	neutral	-0,96	0,02	0,71	0,75	neutral	0,42	neutral	0,26	neutral	0,43	neutral	0,44	1	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,24	medium_impact	0,17	0,56	0,8	31,67	19,84	N	0,34	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13873	13873	A	T	MI.22528	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1537	513	M	L	Ata/Tta	-0,29	0	0	benign	0	neutral	0,71	neutral	1,08	neutral	1,75	neutral	0,16	neutral_impact	-0,1	neutral	0,81	neutral	0,98	neutral	-0,63	0,11	0,67	0,7	disease	0,54	neutral	0,27	neutral	0,4	neutral	0,46	1	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,2	high_impact	2,1	medium_impact	0,45	low_impact	-1,29	0,63	0,8	31,67	19,84	N	0,39	N	0,26	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13873	13873	A	C	MI.22529	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1537	513	M	L	Ata/Cta	-0,29	0	0	benign	0	neutral	0,71	neutral	1,08	neutral	1,75	neutral	0,16	neutral_impact	-0,1	neutral	0,81	neutral	0,98	neutral	-0,71	0,07	0,67	0,7	disease	0,54	neutral	0,27	neutral	0,4	neutral	0,46	1	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,2	high_impact	2,1	medium_impact	0,45	low_impact	-1,29	0,63	0,8	31,67	19,84	N	0,38	N	0,26	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6081	6081	G	T	MI.2253	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	178	60	A	S	Gcc/Tcc	-7,28	0	0	benign	0,03	neutral	0,26	neutral	2,73	neutral	-0,87	neutral	-1,5	low_impact	0,94	damaging	0,53	neutral	0,6	deleterious	2,4	18,82	0,37	0,55	disease	0,54	disease	0,7	neutral	0,31	disease	0,52	0	neutral	0,73	deleterious	0,62	neutral	-6	neutral	0,3	medium_impact	0,66	medium_impact	-0,06	medium_impact	-0,23	0,91	0,95	6,63	22,87	N	0,42	N	0,64	polymorphism	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13874	13874	T	A	MI.22530	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1538	513	M	K	aTa/aAa	-3,96	0	0	benign	0,23	neutral	0,35	neutral	1,16	neutral	2,48	neutral	-1,86	neutral_impact	0,76	neutral	0,75	neutral	0,73	neutral	1,05	10,96	0,31	0,45	neutral	0,34	neutral	0,3	neutral	0,3	neutral	0,44	1	neutral	0,58	deleterious	0,56	neutral	-6	neutral	0,39	medium_impact	-0,25	medium_impact	0,08	medium_impact	-0,51	0,4	0,8	31,67	19,84	N	0,4	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13874	13874	T	C	MI.22531	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1538	513	M	T	aTa/aCa	-3,96	0	0	benign	0	neutral	0,45	neutral	1,04	neutral	1,11	neutral	-1,05	neutral_impact	0,73	neutral	0,84	neutral	0,94	neutral	-0,39	0,41	0,61	0,65	neutral	0,39	neutral	0,27	neutral	0,45	neutral	0,43	1	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,18	medium_impact	-0,54	0,09	0,8	31,67	19,84	N	0,33	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13875	13875	A	T	MI.22532	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1539	513	M	I	atA/atT	-1,21	0	0	benign	0,07	neutral	0,41	neutral	1,03	neutral	0,89	neutral	-0,47	neutral_impact	0,6	neutral	0,78	neutral	0,85	deleterious	-0,05	2,15	0,7	0,75	disease	0,61	neutral	0,22	neutral	0,43	neutral	0,43	2	neutral	0,54	deleterious	0,67	neutral	-6	neutral	0,26	medium_impact	0,32	medium_impact	0,15	medium_impact	-0,66	0,7	0,85	31,67	19,84	N	0,36	N	0,32	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13875	13875	A	C	MI.22533	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1539	513	M	I	atA/atC	-1,21	0	0	benign	0,07	neutral	0,41	neutral	1,03	neutral	0,89	neutral	-0,47	neutral_impact	0,6	neutral	0,78	neutral	0,85	neutral	-0,13	1,55	0,7	0,75	disease	0,61	neutral	0,22	neutral	0,43	neutral	0,43	2	neutral	0,54	deleterious	0,67	neutral	-6	neutral	0,26	medium_impact	0,32	medium_impact	0,15	medium_impact	-0,66	0,7	0,85	31,67	19,84	N	0,35	N	0,32	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13876	13876	A	G	MI.22534	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1540	514	K	E	Aaa/Gaa	-3,96	0	0	benign	0,35	neutral	0,33	neutral	0,86	neutral	-1,28	neutral	-1,14	low_impact	1,72	neutral	0,85	neutral	0,85	deleterious	2,14	17,12	0,47	0,55	neutral	0,38	disease	0,58	neutral	0,47	neutral	0,49	0	neutral	0,61	deleterious	0,49	neutral	-6	deleterious	0,72	medium_impact	-0,49	medium_impact	0,06	medium_impact	0,37	0,8	0,85	18,41	12,18	N	0,34	N	0,5	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13876	13876	A	C	MI.22535	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1540	514	K	Q	Aaa/Caa	-3,96	0	0	possibly_damaging	0,74	neutral	0,34	neutral	0,84	neutral	-1,61	neutral	-1,18	low_impact	0,94	neutral	0,8	neutral	0,86	deleterious	1,98	16,08	0,5	0,6	neutral	0,38	neutral	0,37	neutral	0,28	neutral	0,47	1	neutral	0,78	neutral	0,3	neutral	-3	deleterious	0,69	low_impact	-1,18	medium_impact	0,07	medium_impact	-0,34	0,77	0,85	18,41	12,18	N	0,39	N	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13877	13877	A	C	MI.22536	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1541	514	K	T	aAa/aCa	0,4	0	0	benign	0,35	neutral	0,48	neutral	0,84	neutral	-1,72	neutral	-1,7	neutral_impact	0,19	neutral	0,83	neutral	0,98	neutral	1,43	12,92	0,32	0,5	disease	0,52	neutral	0,26	neutral	0,28	neutral	0,37	3	neutral	0,44	deleterious	0,57	neutral	-6	deleterious	0,7	medium_impact	-0,49	medium_impact	0,21	low_impact	-1,03	0,7	0,85	18,41	12,18	N	0,38	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13877	13877	A	T	MI.22537	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1541	514	K	M	aAa/aTa	0,4	0	0	possibly_damaging	0,9	neutral	0,24	neutral	0,79	deleterious	-3,18	deleterious	-2,55	low_impact	0,82	neutral	0,84	neutral	0,96	deleterious	2,76	21,1	0,31	0,45	disease	0,78	neutral	0,35	neutral	0,31	disease	0,65	3	neutral	0,93	neutral	0,17	neutral	-3	deleterious	0,73	low_impact	-1,65	medium_impact	-0,04	medium_impact	-0,45	0,56	0,8	18,41	12,18	N	0,4	N	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13878	13878	A	C	MI.22538	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1542	514	K	N	aaA/aaC	-0,75	0	0	benign	0,03	neutral	0,35	neutral	0,87	neutral	-1,2	neutral	0,09	neutral_impact	0,36	neutral	0,9	neutral	0,99	deleterious	1,94	15,86	0,65	0,7	disease	0,52	neutral	0,39	neutral	0,3	neutral	0,39	2	neutral	0,63	deleterious	0,66	neutral	-6	deleterious	0,72	medium_impact	0,69	medium_impact	0,08	medium_impact	-0,87	0,87	0,9	18,41	12,18	N	0,42	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13878	13878	A	T	MI.22539	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1542	514	K	N	aaA/aaT	-0,75	0	0	benign	0,03	neutral	0,35	neutral	0,87	neutral	-1,2	neutral	0,09	neutral_impact	0,36	neutral	0,9	neutral	0,99	deleterious	2,02	16,34	0,65	0,7	disease	0,52	neutral	0,39	neutral	0,3	neutral	0,39	2	neutral	0,63	deleterious	0,66	neutral	-6	deleterious	0,72	medium_impact	0,69	medium_impact	0,08	medium_impact	-0,87	0,87	0,9	18,41	12,18	N	0,43	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6082	6082	C	T	MI.2254	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	179	60	A	V	gCc/gTc	7,3	1	0	benign	0,36	deleterious	0,01	neutral	2,87	neutral	0,47	neutral	-2,27	medium_impact	3,39	damaging	0,55	neutral	0,39	deleterious	4,29	24	0,28	0,55	neutral	0,35	disease	0,91	disease	0,54	disease	0,73	5	deleterious	0,99	neutral	0,33	deleterious	1	deleterious	0,65	medium_impact	-0,52	medium_impact	-0,92	high_impact	2,03	0,82	0,9	6,63	22,87	P	0,49	N	0,75	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13879	13879	T	G	MI.22540	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1543	515	S	A	Tcc/Gcc	-7,4	0	0,03	benign	0	neutral	0,54	neutral	0,92	neutral	-0,83	neutral	-0,62	low_impact	1,32	neutral	0,84	neutral	0,88	deleterious	0,35	6,19	0,48	0,55	neutral	0,42	neutral	0,15	neutral	0,31	neutral	0,28	4	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,16	high_impact	2,1	medium_impact	0,27	medium_impact	0	0,39	0,8	31,01	22,72	N	0,35	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13879	13879	T	C	MI.22541	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1543	515	S	P	Tcc/Ccc	-7,4	0	0,03	benign	0,01	neutral	0,25	neutral	0,85	neutral	-2,07	neutral	-0,76	neutral_impact	-0,86	neutral	0,89	neutral	0,96	neutral	-0,16	1,34	0,37	0,5	neutral	0,44	neutral	0,44	neutral	0,22	neutral	0,47	1	neutral	0,75	deleterious	0,62	neutral	-6	neutral	0,2	medium_impact	1,15	medium_impact	-0,03	low_impact	-1,99	0,49	0,8	31,01	22,72	N	0,4	N	0,52	polymorphism	1	0,02	rs879087566	.	.	.	.	MNGIE fibroblasts	.	.	.	.	.	.	.	.	.
chrM	13879	13879	T	A	MI.22542	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1543	515	S	T	Tcc/Acc	-7,4	0	0,03	benign	0	neutral	0,43	neutral	0,95	neutral	-0,44	neutral	-0,16	neutral_impact	-0,06	neutral	0,89	neutral	0,95	neutral	-0,23	0,95	0,47	0,55	neutral	0,39	neutral	0,08	neutral	0,16	neutral	0,25	5	neutral	0,57	deleterious	0,72	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	0,17	low_impact	-1,26	0,7	0,85	31,01	22,72	P	0,58	P	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13880	13880	C	A	MI.22543	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1544	515	S	Y	tCc/tAc	-2,12	0	0	benign	0,17	neutral	1	neutral	0,84	neutral	-2,46	neutral	1,26	low_impact	0,9	neutral	0,91	neutral	0,98	neutral	-0,21	1,04	0,31	0,45	neutral	0,48	neutral	0,4	neutral	0,25	neutral	0,41	2	neutral	0,17	deleterious	0,92	neutral	-6	neutral	0,34	medium_impact	-0,09	high_impact	1,89	medium_impact	-0,38	0,49	0,8	31,01	22,72	N	0,22	N	0,02	polymorphism	1	0,01	rs28359181	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13880	13880	C	T	MI.22544	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1544	515	S	F	tCc/tTc	-2,12	0	0	benign	0,23	neutral	0,71	neutral	0,85	neutral	-2,11	neutral	-0,23	low_impact	1,32	neutral	0,84	neutral	0,64	deleterious	0,85	9,78	0,31	0,5	neutral	0,45	disease	0,51	neutral	0,39	disease	0,51	0	neutral	0,19	deleterious	0,74	neutral	-6	deleterious	0,53	medium_impact	-0,25	medium_impact	0,45	medium_impact	0	0,35	0,8	31,01	22,72	N	0,24	N	0,33	polymorphism	1	0,01	rs28359181	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13880	13880	C	G	MI.22545	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1544	515	S	C	tCc/tGc	-2,12	0	0	possibly_damaging	0,68	neutral	0,18	neutral	0,81	deleterious	-4,4	neutral	-1,52	low_impact	1,87	neutral	0,84	neutral	0,55	deleterious	2,28	18,04	0,39	0,5	disease	0,87	disease	0,53	neutral	0,38	disease	0,61	2	neutral	0,85	neutral	0,25	neutral	-3	deleterious	0,66	low_impact	-1,06	medium_impact	-0,13	medium_impact	0,51	0,55	0,8	31,01	22,72	N	0,36	N	0,49	polymorphism	1	0,03	rs28359181	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13882	13882	C	G	MI.22546	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1546	516	P	A	Cca/Gca	-5,33	0	0	possibly_damaging	0,64	neutral	0,55	neutral	1	neutral	0,4	deleterious	-4,12	low_impact	1,61	neutral	0,86	neutral	0,9	neutral	1,71	14,49	0,45	0,55	neutral	0,44	neutral	0,37	neutral	0,38	neutral	0,46	1	neutral	0,6	neutral	0,46	neutral	-3	deleterious	0,51	medium_impact	-0,98	medium_impact	0,28	medium_impact	0,27	0,82	0,85	21,23	16,75	N	0,29	N	0,38	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13882	13882	C	T	MI.22547	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1546	516	P	S	Cca/Tca	-5,33	0	0	benign	0,26	neutral	0,45	neutral	0,98	neutral	0,3	deleterious	-3,6	low_impact	0,88	neutral	0,87	neutral	0,97	deleterious	2,5	19,49	0,55	0,6	neutral	0,42	disease	0,55	neutral	0,22	neutral	0,45	1	neutral	0,46	deleterious	0,6	neutral	-6	deleterious	0,58	medium_impact	-0,32	medium_impact	0,18	medium_impact	-0,4	0,28	0,8	21,23	16,75	N	0,34	N	0,26	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13882	13882	C	A	MI.22548	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1546	516	P	T	Cca/Aca	-5,33	0	0	benign	0,2	neutral	0,43	neutral	0,98	neutral	0,05	deleterious	-3,68	low_impact	1,61	neutral	0,87	neutral	0,89	deleterious	0,6	8,17	0,48	0,55	disease	0,53	neutral	0,5	neutral	0,23	neutral	0,43	1	neutral	0,48	deleterious	0,62	neutral	-6	neutral	0,2	medium_impact	-0,17	medium_impact	0,17	medium_impact	0,27	0,79	0,85	21,23	16,75	N	0,34	N	0,56	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13883	13883	C	A	MI.22549	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1547	516	P	Q	cCa/cAa	-0,98	0	0	probably_damaging	0,96	neutral	0,33	neutral	0,96	neutral	-0,08	deleterious	-4,06	low_impact	1,26	neutral	0,83	neutral	0,76	deleterious	4,07	23,7	0,35	0,5	neutral	0,49	disease	0,58	neutral	0,32	neutral	0,46	1	neutral	0,96	neutral	0,19	neutral	-2	deleterious	0,71	low_impact	-2,06	medium_impact	0,06	medium_impact	-0,05	0,55	0,8	21,23	16,75	N	0,31	N	0,68	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6082	6082	C	A	MI.2255	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	179	60	A	D	gCc/gAc	7,3	1	0	possibly_damaging	0,62	deleterious	0	neutral	2,65	deleterious	-4,13	deleterious	-3,4	high_impact	4,25	neutral	0,65	neutral	0,42	deleterious	4,5	24,3	0,12	0,55	disease	0,78	disease	0,93	disease	0,66	disease	0,79	6	deleterious	1	neutral	0,19	deleterious	5	deleterious	0,71	medium_impact	-0,96	low_impact	-1,48	high_impact	2,83	0,74	0,9	6,63	22,87	P	0,55	P	0,89	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13883	13883	C	T	MI.22550	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1547	516	P	L	cCa/cTa	-0,98	0	0	possibly_damaging	0,83	neutral	0,68	neutral	1,08	neutral	-0,45	deleterious	-5,71	low_impact	1	neutral	0,84	neutral	0,72	deleterious	3,03	22,3	0,5	0,6	neutral	0,34	disease	0,68	neutral	0,38	neutral	0,48	0	neutral	0,8	neutral	0,43	neutral	-3	deleterious	0,58	low_impact	-1,4	medium_impact	0,41	medium_impact	-0,29	0,73	0,85	21,23	16,75	N	0,22	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13883	13883	C	G	MI.22551	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1547	516	P	R	cCa/cGa	-0,98	0	0	probably_damaging	0,96	neutral	0,37	neutral	0,93	neutral	-0,32	deleterious	-4,75	low_impact	1,84	neutral	0,83	neutral	0,62	deleterious	3,62	23,2	0,43	0,55	disease	0,5	disease	0,78	neutral	0,42	disease	0,63	3	neutral	0,96	neutral	0,21	neutral	-2	deleterious	0,73	low_impact	-2,06	medium_impact	0,11	medium_impact	0,48	0,58	0,8	21,23	16,75	N	0,26	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13885	13885	C	A	MI.22552	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1549	517	L	M	Cta/Ata	-9	0	0	benign	0,08	neutral	0,22	neutral	0,97	neutral	-0,76	neutral	0,62	low_impact	0,9	neutral	0,8	neutral	0,83	deleterious	2,25	17,86	0,31	0,45	disease	0,72	neutral	0,22	neutral	0,18	disease	0,52	0	neutral	0,76	deleterious	0,57	neutral	-6	deleterious	0,61	medium_impact	0,26	medium_impact	-0,07	medium_impact	-0,38	0,72	0,85	29,85	17,09	N	0,46	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13885	13885	C	G	MI.22553	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1549	517	L	V	Cta/Gta	-9	0	0	benign	0,01	neutral	0,5	neutral	0,98	neutral	-0,56	neutral	0,03	neutral_impact	0,64	neutral	0,81	neutral	0,85	neutral	-0,1	1,75	0,35	0,5	disease	0,54	neutral	0,29	neutral	0,32	neutral	0,5	0	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,33	medium_impact	1,15	medium_impact	0,23	medium_impact	-0,62	0,49	0,8	29,85	17,09	N	0,32	N	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13886	13886	T	G	MI.22554	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1550	517	L	R	cTa/cGa	-2,35	0	0,01	possibly_damaging	0,47	neutral	0,35	neutral	1,01	neutral	0,11	neutral	0,64	low_impact	1,09	neutral	0,74	neutral	0,73	neutral	0,95	10,39	0,32	0,5	neutral	0,31	disease	0,75	neutral	0,47	disease	0,59	2	neutral	0,61	neutral	0,44	neutral	-3	deleterious	0,46	medium_impact	-0,7	medium_impact	0,08	medium_impact	-0,21	0,49	0,8	29,85	17,09	N	0,34	N	0,21	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13886	13886	T	C	MI.22555	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1550	517	L	P	cTa/cCa	-2,35	0	0,01	benign	0,01	neutral	0,21	neutral	0,98	neutral	-0,59	neutral	0,23	neutral_impact	0,34	neutral	0,9	neutral	0,78	deleterious	0,82	9,59	0,22	0,45	neutral	0,41	disease	0,73	neutral	0,25	neutral	0,5	0	neutral	0,79	deleterious	0,6	neutral	-6	neutral	0,24	medium_impact	1,15	medium_impact	-0,09	medium_impact	-0,89	0,43	0,8	29,85	17,09	N	0,35	N	0,02	polymorphism	1	0,01	rs28359182	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13886	13886	T	A	MI.22556	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1550	517	L	Q	cTa/cAa	-2,35	0	0,01	possibly_damaging	0,55	neutral	0,3	neutral	1,01	neutral	0,3	neutral	1,33	low_impact	0,82	neutral	0,86	neutral	0,94	neutral	1,19	11,7	0,3	0,45	neutral	0,41	disease	0,56	neutral	0,24	neutral	0,45	1	neutral	0,69	neutral	0,38	neutral	-3	deleterious	0,45	medium_impact	-0,83	medium_impact	0,03	medium_impact	-0,45	0,48	0,8	29,85	17,09	N	0,35	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13888	13888	T	A	MI.22557	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1552	518	C	S	Tgc/Agc	-7,4	0	0	benign	0	neutral	0,41	neutral	1,13	neutral	3,99	neutral	2,16	neutral_impact	-1,62	neutral	0,85	neutral	0,91	neutral	-0,11	1,64	0,42	0,55	neutral	0,23	neutral	0,18	neutral	0,17	neutral	0,29	4	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,15	low_impact	-2,68	0,48	0,8	31,51	23,2	N	0,42	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13888	13888	T	G	MI.22558	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1552	518	C	G	Tgc/Ggc	-7,4	0	0	benign	0	neutral	0,34	neutral	1,03	neutral	2,24	neutral	0,67	neutral_impact	-0,55	neutral	0,81	neutral	0,82	neutral	-0,08	1,88	0,31	0,5	neutral	0,3	neutral	0,31	neutral	0,36	neutral	0,43	1	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,07	low_impact	-1,71	0,36	0,8	31,51	23,2	N	0,31	N	0,24	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13888	13888	T	C	MI.22559	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1552	518	C	R	Tgc/Cgc	-7,4	0	0	benign	0	neutral	0,34	neutral	1,06	neutral	2,91	neutral	2,18	neutral_impact	-0,34	neutral	0,86	neutral	0,93	deleterious	0,05	3,07	0,29	0,45	neutral	0,27	disease	0,55	neutral	0,39	neutral	0,43	1	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,17	high_impact	2,1	medium_impact	0,07	low_impact	-1,51	0,21	0,8	31,51	23,2	N	0,28	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6082	6082	C	G	MI.2256	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	179	60	A	G	gCc/gGc	7,3	1	0	benign	0,17	deleterious	0	neutral	2,69	neutral	-1,94	neutral	-2,3	medium_impact	2,92	damaging	0,56	neutral	0,61	deleterious	3,84	23,4	0,19	0,55	neutral	0,41	disease	0,8	neutral	0,35	disease	0,53	1	deleterious	1	neutral	0,42	deleterious	1	neutral	0,34	medium_impact	-0,11	low_impact	-1,48	medium_impact	1,6	0,81	0,9	6,63	22,87	P	0,53	P	0,56	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13889	13889	G	T	MI.22560	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1553	518	C	F	tGc/tTc	-1,21	0	0,01	benign	0	neutral	0,72	neutral	1,04	neutral	2,52	neutral	0,01	neutral_impact	-0,7	neutral	0,77	neutral	0,81	neutral	-0,1	1,74	0,31	0,5	neutral	0,4	neutral	0,41	neutral	0,32	neutral	0,45	1	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,15	high_impact	2,1	medium_impact	0,46	low_impact	-1,84	0,5	0,8	31,51	23,2	N	0,3	N	0,15	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13889	13889	G	A	MI.22561	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1553	518	C	Y	tGc/tAc	-1,21	0	0,01	benign	0	neutral	1	neutral	1,03	neutral	2,14	neutral	1,14	neutral_impact	-0,7	neutral	0,9	neutral	0,88	neutral	-0,87	0,03	0,37	0,5	disease	0,58	neutral	0,39	neutral	0,2	disease	0,58	2	neutral	0	deleterious	1	neutral	-6	neutral	0,18	high_impact	2,1	high_impact	1,89	low_impact	-1,84	0,56	0,8	31,51	23,2	N	0,29	N	0,06	polymorphism	1	0	.	.	.	.	.	head/neck tumor	.	.	.	.	.	.	.	.	.
chrM	13889	13889	G	C	MI.22562	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1553	518	C	S	tGc/tCc	-1,21	0	0,01	benign	0	neutral	0,41	neutral	1,13	neutral	3,99	neutral	2,16	neutral_impact	-1,62	neutral	0,85	neutral	0,91	neutral	-0,42	0,34	0,42	0,55	neutral	0,23	neutral	0,18	neutral	0,17	neutral	0,29	4	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,12	high_impact	2,1	medium_impact	0,15	low_impact	-2,68	0,48	0,8	31,51	23,2	N	0,42	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13890	13890	C	G	MI.22563	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1554	518	C	W	tgC/tgG	-2,12	0	0	benign	0,01	neutral	0,18	neutral	1	neutral	-0,74	neutral	-0,41	neutral_impact	0	neutral	0,78	neutral	0,63	neutral	1,17	11,58	0,28	0,45	disease	0,64	disease	0,51	neutral	0,39	neutral	0,48	0	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,21	medium_impact	1,15	medium_impact	-0,13	low_impact	-1,2	0,39	0,8	31,51	23,2	N	0,33	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13890	13890	C	A	MI.22564	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1554	518	C	W	tgC/tgA	-2,12	0	0	benign	0,01	neutral	0,18	neutral	1	neutral	-0,74	neutral	-0,41	neutral_impact	0	neutral	0,78	neutral	0,63	neutral	1,46	13,08	0,28	0,45	disease	0,64	disease	0,51	neutral	0,39	neutral	0,48	0	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,21	medium_impact	1,15	medium_impact	-0,13	low_impact	-1,2	0,39	0,8	31,51	23,2	N	0,33	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13891	13891	A	C	MI.22565	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1555	519	T	P	Aca/Cca	-3,5	0	0	benign	0,03	neutral	0,25	neutral	0,95	neutral	-0,91	neutral	-0,82	low_impact	0,95	neutral	0,83	neutral	0,98	neutral	1,51	13,39	0,18	0,45	disease	0,59	neutral	0,48	neutral	0,42	disease	0,58	2	neutral	0,74	deleterious	0,61	neutral	-6	deleterious	0,63	medium_impact	0,69	medium_impact	-0,03	medium_impact	-0,34	0,61	0,8	20,56	13,16	N	0,37	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13891	13891	A	T	MI.22566	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1555	519	T	S	Aca/Tca	-3,5	0	0	benign	0,27	neutral	0,51	neutral	1,01	neutral	0,08	neutral	-0,79	neutral_impact	0,68	neutral	0,84	neutral	0,98	neutral	-0,14	1,46	0,48	0,55	disease	0,51	neutral	0,26	neutral	0,26	neutral	0,36	3	neutral	0,39	deleterious	0,62	neutral	-6	neutral	0,39	medium_impact	-0,34	medium_impact	0,24	medium_impact	-0,58	0,55	0,8	20,56	13,16	N	0,38	N	0,33	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13891	13891	A	G	MI.22567	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1555	519	T	A	Aca/Gca	-3,5	0	0	benign	0,02	neutral	0,61	neutral	0,99	neutral	-0,18	neutral	-1,21	low_impact	1,26	neutral	0,84	neutral	0,97	neutral	-0,3	0,67	0,54	0,6	neutral	0,27	neutral	0,26	neutral	0,45	neutral	0,43	1	neutral	0,36	deleterious	0,8	neutral	-6	neutral	0,11	medium_impact	0,86	medium_impact	0,34	medium_impact	-0,05	0,29	0,8	20,56	13,16	N	0,32	N	0,14	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13892	13892	C	T	MI.22568	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1556	519	T	M	aCa/aTa	-10,83	0	0	benign	0,05	neutral	0,24	neutral	0,98	neutral	-0,28	neutral	-1,16	low_impact	1,6	neutral	0,87	neutral	0,97	deleterious	0,67	8,6	0,35	0,5	neutral	0,45	neutral	0,37	neutral	0,32	neutral	0,48	0	neutral	0,74	deleterious	0,6	neutral	-6	neutral	0,27	medium_impact	0,47	medium_impact	-0,04	medium_impact	0,26	0,67	0,85	20,56	13,16	N	0,42	N	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13892	13892	C	A	MI.22569	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1556	519	T	K	aCa/aAa	-10,83	0	0	possibly_damaging	0,46	neutral	0,43	neutral	0,91	neutral	-2,1	neutral	-1,8	medium_impact	2,03	neutral	0,79	neutral	0,75	neutral	1,57	13,68	0,29	0,45	disease	0,58	disease	0,67	disease	0,61	disease	0,56	1	neutral	0,53	deleterious	0,49	NA	0	deleterious	0,57	medium_impact	-0,68	medium_impact	0,17	medium_impact	0,65	0,57	0,8	20,56	13,16	N	0,25	N	0,74	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6084	6084	C	A	MI.2257	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	181	61	H	N	Cat/Aat	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	-1,17	deleterious	-10,98	deleterious	-4,46	high_impact	5,19	damaging	0,53	damaging	0,02	deleterious	3,89	23,5	0,28	0,55	disease	0,77	disease	0,84	disease	0,72	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,44	0,9	2,92	6,76	N	0,49	N	0,86	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13894	13894	T	G	MI.22570	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1558	520	F	V	Ttt/Gtt	-4,42	0	0	probably_damaging	0,91	neutral	0,53	neutral	1,02	neutral	0,37	deleterious	-2,9	medium_impact	2,29	neutral	0,79	neutral	0,29	deleterious	2,98	22,2	0,33	0,5	neutral	0,45	disease	0,72	disease	0,63	disease	0,71	4	neutral	0,9	neutral	0,31	deleterious	1	deleterious	0,74	low_impact	-1,7	medium_impact	0,26	medium_impact	0,89	0,52	0,8	28,19	17,59	N	0,17	N	0,8	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13894	13894	T	C	MI.22571	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1558	520	F	L	Ttt/Ctt	-4,42	0	0	possibly_damaging	0,81	neutral	0,71	neutral	1,03	neutral	0,52	deleterious	-2,65	low_impact	1,08	neutral	0,81	neutral	0,81	deleterious	2,67	20,6	0,36	0,5	neutral	0,44	disease	0,52	neutral	0,48	neutral	0,49	0	neutral	0,78	neutral	0,45	neutral	-3	deleterious	0,71	low_impact	-1,34	medium_impact	0,45	medium_impact	-0,22	0,7	0,85	28,19	17,59	N	0,21	N	0,8	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13894	13894	T	A	MI.22572	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1558	520	F	I	Ttt/Att	-4,42	0	0	probably_damaging	0,94	neutral	0,42	neutral	1	neutral	0,04	deleterious	-2,65	low_impact	1,48	neutral	0,82	neutral	0,82	deleterious	3,37	22,9	0,2	0,45	disease	0,54	disease	0,63	disease	0,61	disease	0,69	4	neutral	0,93	neutral	0,24	neutral	-2	deleterious	0,76	low_impact	-1,88	medium_impact	0,16	medium_impact	0,15	0,52	0,8	28,19	17,59	N	0,26	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13895	13895	T	G	MI.22573	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1559	520	F	C	tTt/tGt	-2,35	0	0	probably_damaging	0,99	neutral	0,17	neutral	0,95	neutral	-2,57	deleterious	-3,61	low_impact	1,94	neutral	0,71	damaging	0,2	deleterious	4,18	23,8	0,28	0,45	disease	0,82	disease	0,83	disease	0,64	disease	0,8	6	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,82	low_impact	-2,64	medium_impact	-0,15	medium_impact	0,57	0,26	0,8	28,19	17,59	N	0,23	N	0,79	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13895	13895	T	A	MI.22574	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1559	520	F	Y	tTt/tAt	-2,35	0	0	benign	0,12	neutral	1	neutral	1	neutral	-0,04	neutral	0,1	neutral_impact	-0,48	neutral	0,8	neutral	0,95	deleterious	2,79	21,3	0,34	0,5	neutral	0,24	neutral	0,46	neutral	0,27	neutral	0,46	1	neutral	0,11	deleterious	0,94	neutral	-6	deleterious	0,7	medium_impact	0,08	high_impact	1,89	low_impact	-1,64	0,58	0,8	28,19	17,59	N	0,24	N	0,7	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13895	13895	T	C	MI.22575	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1559	520	F	S	tTt/tCt	-2,35	0	0	probably_damaging	0,97	neutral	0,49	neutral	1,12	neutral	1,56	deleterious	-2,67	low_impact	0,93	neutral	0,82	neutral	0,96	deleterious	3,12	22,6	0,41	0,5	neutral	0,35	disease	0,63	neutral	0,43	neutral	0,49	0	neutral	0,97	neutral	0,26	neutral	-2	deleterious	0,73	low_impact	-2,18	medium_impact	0,22	medium_impact	-0,35	0,44	0,8	28,19	17,59	N	0,3	N	0,38	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13896	13896	T	G	MI.22576	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1560	520	F	L	ttT/ttG	-4,87	0	0	possibly_damaging	0,81	neutral	0,71	neutral	1,03	neutral	0,52	deleterious	-2,65	low_impact	1,08	neutral	0,81	neutral	0,81	deleterious	3,04	22,4	0,36	0,5	neutral	0,44	disease	0,52	neutral	0,48	neutral	0,49	0	neutral	0,78	neutral	0,45	neutral	-3	deleterious	0,71	low_impact	-1,34	medium_impact	0,45	medium_impact	-0,22	0,7	0,85	28,19	17,59	N	0,21	N	0,8	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13896	13896	T	A	MI.22577	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1560	520	F	L	ttT/ttA	-4,87	0	0	possibly_damaging	0,81	neutral	0,71	neutral	1,03	neutral	0,52	deleterious	-2,65	low_impact	1,08	neutral	0,81	neutral	0,81	deleterious	3,11	22,5	0,36	0,5	neutral	0,44	disease	0,52	neutral	0,48	neutral	0,49	0	neutral	0,78	neutral	0,45	neutral	-3	deleterious	0,71	low_impact	-1,34	medium_impact	0,45	medium_impact	-0,22	0,7	0,85	28,19	17,59	N	0,21	N	0,8	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13897	13897	T	A	MI.22578	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1561	521	Y	N	Tat/Aat	-4,64	0	0	benign	0,01	neutral	0,34	neutral	1,07	neutral	0,96	neutral	1,95	neutral_impact	-0,79	neutral	0,86	neutral	0,97	neutral	-0,24	0,89	0,44	0,55	neutral	0,32	neutral	0,29	neutral	0,26	neutral	0,45	1	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,36	medium_impact	1,15	medium_impact	0,07	low_impact	-1,92	0,32	0,8	31,18	20,07	N	0,31	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13897	13897	T	C	MI.22579	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1561	521	Y	H	Tat/Cat	-4,64	0	0	benign	0,02	neutral	0,55	neutral	1,02	neutral	0,31	neutral	0,57	neutral_impact	0,14	neutral	0,74	neutral	0,9	neutral	-1	0,02	0,62	0,65	neutral	0,46	neutral	0,12	neutral	0,26	neutral	0,24	5	neutral	0,43	deleterious	0,77	neutral	-6	neutral	0,14	medium_impact	0,86	medium_impact	0,28	low_impact	-1,08	0,37	0,8	31,18	20,07	N	0,38	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6084	6084	C	G	MI.2258	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	181	61	H	D	Cat/Gat	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	-1,17	deleterious	-12,35	deleterious	-5,74	high_impact	5,19	damaging	0,48	damaging	0,02	deleterious	3,75	23,3	0,2	0,55	neutral	0,37	disease	0,88	disease	0,81	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,39	0,9	2,92	6,76	N	0,42	N	0,97	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13897	13897	T	G	MI.22580	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1561	521	Y	D	Tat/Gat	-4,64	0	0	benign	0,26	neutral	0,26	neutral	0,97	neutral	-0,84	neutral	0,18	neutral_impact	0,76	neutral	0,8	neutral	0,78	deleterious	2,41	18,86	0,36	0,5	neutral	0,3	disease	0,65	disease	0,58	disease	0,68	4	neutral	0,69	deleterious	0,5	neutral	-6	deleterious	0,47	medium_impact	-0,32	medium_impact	-0,02	medium_impact	-0,51	0,42	0,8	31,18	20,07	N	0,3	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13898	13898	A	C	MI.22581	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1562	521	Y	S	tAt/tCt	0,17	0	0	benign	0,18	neutral	0,47	neutral	1,12	neutral	1,35	neutral	1,22	neutral_impact	-0,12	neutral	0,87	neutral	0,96	deleterious	0,8	9,46	0,36	0,5	neutral	0,22	neutral	0,41	neutral	0,33	neutral	0,44	1	neutral	0,44	deleterious	0,65	neutral	-6	neutral	0,42	medium_impact	-0,12	medium_impact	0,2	low_impact	-1,31	0,33	0,8	31,18	20,07	N	0,3	N	0,15	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13898	13898	A	G	MI.22582	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1562	521	Y	C	tAt/tGt	0,17	0	0	possibly_damaging	0,89	neutral	0,18	neutral	0,93	neutral	-2,88	neutral	-1,15	low_impact	1,79	neutral	0,72	neutral	0,42	deleterious	3,63	23,2	0,4	0,5	disease	0,84	disease	0,71	disease	0,51	disease	0,67	3	neutral	0,94	neutral	0,15	neutral	-3	deleterious	0,74	low_impact	-1,61	medium_impact	-0,13	medium_impact	0,43	0,15	0,8	31,18	20,07	N	0,32	N	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13898	13898	A	T	MI.22583	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1562	521	Y	F	tAt/tTt	0,17	0	0	benign	0,41	neutral	0,73	neutral	1	neutral	-0,08	neutral	-0,78	low_impact	1,1	neutral	0,78	neutral	0,86	deleterious	0,78	9,31	0,47	0,55	disease	0,63	neutral	0,37	neutral	0,39	disease	0,62	2	neutral	0,31	deleterious	0,66	neutral	-6	deleterious	0,5	medium_impact	-0,6	medium_impact	0,47	medium_impact	-0,2	0,41	0,8	31,18	20,07	N	0,28	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13900	13900	T	A	MI.22584	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1564	522	F	I	Ttc/Atc	-1,89	0	0	probably_damaging	1	neutral	0,41	neutral	0,35	deleterious	-3,46	deleterious	-5,13	medium_impact	3,4	damaging	0,55	damaging	0,15	deleterious	4,74	24,7	0,18	0,45	neutral	0,47	disease	0,81	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,15	medium_impact	1,9	0,61	0,8	28,86	7,21	N	0,29	N	0,95	polymorphism	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13900	13900	T	G	MI.22585	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1564	522	F	V	Ttc/Gtc	-1,89	0	0	probably_damaging	1	neutral	0,51	neutral	0,37	deleterious	-3,18	deleterious	-5,97	high_impact	3,75	neutral	0,61	damaging	0,08	deleterious	4,35	24,1	0,35	0,5	disease	0,53	disease	0,85	disease	0,78	disease	0,78	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,24	high_impact	2,22	0,62	0,8	28,86	7,21	N	0,32	N	0,95	polymorphism	0,98	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13900	13900	T	C	MI.22586	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1564	522	F	L	Ttc/Ctc	-1,89	0	0	probably_damaging	1	neutral	0,67	neutral	0,4	neutral	-2,8	deleterious	-5,13	medium_impact	2,23	damaging	0,54	damaging	0,14	deleterious	4,36	24,1	0,41	0,5	disease	0,52	disease	0,74	disease	0,7	disease	0,55	1	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,4	medium_impact	0,83	0,61	0,8	28,86	7,21	N	0,16	N	0,92	polymorphism	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13901	13901	T	A	MI.22587	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1565	522	F	Y	tTc/tAc	4,52	1	0	probably_damaging	1	neutral	1	neutral	0,33	deleterious	-3,92	deleterious	-2,61	medium_impact	3,2	neutral	0,63	damaging	0,1	deleterious	4,42	24,2	0,39	0,5	disease	0,78	disease	0,74	disease	0,71	disease	0,74	5	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,82	low_impact	-3,6	high_impact	1,89	medium_impact	1,72	0,62	0,8	28,86	7,21	N	0,42	N	0,88	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13901	13901	T	G	MI.22588	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1565	522	F	C	tTc/tGc	4,52	1	0	probably_damaging	1	neutral	0,18	neutral	0,29	deleterious	-5,8	deleterious	-6,79	high_impact	3,75	neutral	0,61	damaging	0,06	deleterious	4,27	24	0,24	0,45	disease	0,86	disease	0,87	disease	0,78	disease	0,86	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,13	high_impact	2,22	0,34	0,8	28,86	7,21	N	0,48	N	0,99	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13901	13901	T	C	MI.22589	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1565	522	F	S	tTc/tCc	4,52	1	0	probably_damaging	1	neutral	0,43	neutral	0,34	deleterious	-3,7	deleterious	-6,76	medium_impact	3,06	damaging	0,57	damaging	0,1	deleterious	4,4	24,1	0,34	0,5	disease	0,66	disease	0,83	disease	0,74	disease	0,77	5	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,17	medium_impact	1,59	0,52	0,8	28,86	7,21	N	0,39	N	0,97	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6084	6084	C	T	MI.2259	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	181	61	H	Y	Cat/Tat	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	-1,17	deleterious	-10,99	deleterious	-3,83	high_impact	4,84	damaging	0,56	damaging	0,02	deleterious	3,64	23,2	0,29	0,55	disease	0,92	disease	0,91	disease	0,75	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,35	0,9	2,92	6,76	P	0,54	P	0,72	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13902	13902	C	G	MI.22590	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1566	522	F	L	ttC/ttG	3,61	1	0	probably_damaging	1	neutral	0,67	neutral	0,4	neutral	-2,8	deleterious	-5,13	medium_impact	2,23	damaging	0,54	damaging	0,14	deleterious	4,56	24,4	0,41	0,5	disease	0,52	disease	0,74	disease	0,7	disease	0,55	1	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,4	medium_impact	0,83	0,61	0,8	28,86	7,21	N	0,37	N	0,92	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13902	13902	C	A	MI.22591	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1566	522	F	L	ttC/ttA	3,61	1	0	probably_damaging	1	neutral	0,67	neutral	0,4	neutral	-2,8	deleterious	-5,13	medium_impact	2,23	damaging	0,54	damaging	0,14	deleterious	4,8	24,8	0,41	0,5	disease	0,52	disease	0,74	disease	0,7	disease	0,55	1	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,4	medium_impact	0,83	0,61	0,8	28,86	7,21	N	0,39	N	0,92	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13903	13903	T	G	MI.22592	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1567	523	S	A	Tcc/Gcc	-1,44	0	0	probably_damaging	1	neutral	0,55	neutral	0,79	neutral	-1,86	deleterious	-2,58	high_impact	3,61	neutral	0,72	damaging	0,23	deleterious	3,8	23,4	0,41	0,5	neutral	0,44	disease	0,58	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,73	low_impact	-3,6	medium_impact	0,28	high_impact	2,1	0,77	0,85	4,98	6,89	N	0,26	N	0,49	disease_causing	0,53	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13903	13903	T	A	MI.22593	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1567	523	S	T	Tcc/Acc	-1,44	0	0	probably_damaging	1	neutral	0,44	neutral	0,8	neutral	-1,74	neutral	-2,45	medium_impact	2,22	neutral	0,8	neutral	0,51	deleterious	3,88	23,5	0,32	0,5	disease	0,58	disease	0,63	neutral	0,46	neutral	0,48	0	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,18	medium_impact	0,83	0,85	0,9	4,98	6,89	N	0,24	N	0,71	disease_causing	0,79	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13903	13903	T	C	MI.22594	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1567	523	S	P	Tcc/Ccc	-1,44	0	0	probably_damaging	1	neutral	0,22	neutral	0,72	deleterious	-4,25	deleterious	-4,35	medium_impact	2,71	neutral	0,64	damaging	0,2	deleterious	4,11	23,7	0,18	0,45	disease	0,76	disease	0,83	disease	0,75	disease	0,79	6	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	-0,07	medium_impact	1,27	0,66	0,8	4,98	6,89	N	0,25	N	0,98	disease_causing	0,96	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13904	13904	C	T	MI.22595	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1568	523	S	F	tCc/tTc	5,44	0,99	0	probably_damaging	1	neutral	0,71	neutral	0,86	neutral	-1	deleterious	-5,04	low_impact	1,64	neutral	0,75	damaging	0,25	deleterious	4,44	24,2	0,28	0,45	neutral	0,46	disease	0,84	disease	0,65	disease	0,56	1	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,45	medium_impact	0,3	0,44	0,8	4,98	6,89	N	0,39	N	0,99	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13904	13904	C	G	MI.22596	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1568	523	S	C	tCc/tGc	5,44	0,99	0	probably_damaging	1	neutral	0,18	neutral	0,72	deleterious	-4,16	deleterious	-4,31	high_impact	3,61	neutral	0,69	damaging	0,14	deleterious	3,73	23,3	0,26	0,45	disease	0,77	disease	0,83	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	-0,13	high_impact	2,1	0,73	0,85	4,98	6,89	N	0,47	N	0,99	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13904	13904	C	A	MI.22597	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1568	523	S	Y	tCc/tAc	5,44	0,99	0	probably_damaging	1	neutral	1	neutral	0,73	deleterious	-3,32	deleterious	-5,09	medium_impact	3,06	neutral	0,73	damaging	0,15	deleterious	4,26	23,9	0,21	0,45	disease	0,64	disease	0,86	disease	0,73	disease	0,79	6	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,82	low_impact	-3,6	high_impact	1,89	medium_impact	1,59	0,74	0,85	4,98	6,89	N	0,41	N	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13906	13906	A	G	MI.22598	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1570	524	N	D	Aac/Gac	-9,46	0	0	possibly_damaging	0,85	neutral	0,24	neutral	0,89	neutral	-1,97	deleterious	-2,7	medium_impact	2,65	neutral	0,69	neutral	0,54	deleterious	2,41	18,91	0,62	0,65	neutral	0,44	disease	0,7	disease	0,74	disease	0,72	4	neutral	0,89	neutral	0,2	NA	0	deleterious	0,57	low_impact	-1,46	medium_impact	-0,04	medium_impact	1,22	0,72	0,85	8,79	11,75	N	0,35	N	0,58	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13906	13906	A	T	MI.22599	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1570	524	N	Y	Aac/Tac	-9,46	0	0	probably_damaging	0,97	neutral	1	neutral	0,87	neutral	-2,78	deleterious	-4,42	medium_impact	2,31	neutral	0,8	neutral	0,45	deleterious	3,81	23,4	0,37	0,5	neutral	0,36	disease	0,83	disease	0,7	disease	0,75	5	neutral	0,97	deleterious	0,52	deleterious	1	deleterious	0,71	low_impact	-2,18	high_impact	1,89	medium_impact	0,91	0,55	0,8	8,79	11,75	N	0,19	N	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8632	8632	T	C	MI.226	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	106	36	Y	H	Tat/Cat	-10,05	0	0	benign	0	neutral	0,46	neutral	4,41	neutral	0,72	neutral	1,15	neutral_impact	0,55	neutral	0,88	neutral	0,93	deleterious	0,37	6,38	0,71	0,75	disease	0,62	neutral	0,32	neutral	0,23	disease	0,61	2	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,19	high_impact	2,09	medium_impact	0,25	medium_impact	-0,63	0,41	0,9	29,2	23,72	N	0,36	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6085	6085	A	G	MI.2260	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	182	61	H	R	cAt/cGt	4,52	1	0	probably_damaging	1	deleterious	0	neutral	-1,17	deleterious	-12,45	deleterious	-5,1	high_impact	5,19	damaging	0,57	damaging	0,03	deleterious	2,91	21,9	0,27	0,55	disease	0,88	disease	0,92	disease	0,77	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,39	0,9	2,92	6,76	P	0,56	P	0,85	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13906	13906	A	C	MI.22600	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1570	524	N	H	Aac/Cac	-9,46	0	0	probably_damaging	0,98	neutral	0,55	neutral	0,87	neutral	-2,71	deleterious	-3,08	medium_impact	3	neutral	0,72	neutral	0,52	deleterious	3,19	22,7	0,44	0,55	disease	0,6	disease	0,76	disease	0,74	disease	0,75	5	deleterious	0,98	neutral	0,29	deleterious	1	deleterious	0,76	low_impact	-2,35	medium_impact	0,28	medium_impact	1,54	0,66	0,8	8,79	11,75	N	0,25	N	0,38	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13907	13907	A	C	MI.22601	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1571	524	N	T	aAc/aCc	2,23	0	0	benign	0,2	neutral	0,44	neutral	1,01	neutral	0,13	neutral	-0,94	low_impact	1,17	neutral	0,86	neutral	0,97	deleterious	0,34	6,06	0,45	0,55	neutral	0,39	disease	0,59	neutral	0,39	neutral	0,47	1	neutral	0,47	deleterious	0,62	neutral	-6	neutral	0,19	medium_impact	-0,17	medium_impact	0,18	medium_impact	-0,13	0,62	0,8	8,79	11,75	N	0,34	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13907	13907	A	G	MI.22602	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1571	524	N	S	aAc/aGc	2,23	0	0	possibly_damaging	0,74	neutral	0,47	neutral	1,05	neutral	0,41	neutral	-1,82	low_impact	1,3	neutral	0,85	neutral	0,96	neutral	1,5	13,32	0,68	0,7	neutral	0,35	disease	0,51	neutral	0,41	neutral	0,45	1	neutral	0,73	neutral	0,37	neutral	-3	neutral	0,43	low_impact	-1,18	medium_impact	0,2	medium_impact	-0,02	0,41	0,8	8,79	11,75	N	0,33	N	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13907	13907	A	T	MI.22603	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1571	524	N	I	aAc/aTc	2,23	0	0	benign	0,17	neutral	0,42	neutral	0,91	neutral	-1,26	deleterious	-4,32	low_impact	1,7	neutral	0,86	neutral	0,95	deleterious	2,22	17,65	0,35	0,5	disease	0,59	disease	0,84	neutral	0,45	disease	0,57	1	neutral	0,5	deleterious	0,63	neutral	-6	neutral	0,26	medium_impact	-0,09	medium_impact	0,16	medium_impact	0,35	0,44	0,8	8,79	11,75	N	0,34	N	0,16	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13908	13908	C	A	MI.22604	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1572	524	N	K	aaC/aaA	-1,21	0	0	possibly_damaging	0,88	neutral	0,36	neutral	0,92	neutral	-1,1	deleterious	-3,15	medium_impact	2,65	neutral	0,71	neutral	0,58	deleterious	3,05	22,4	0,62	0,65	neutral	0,35	disease	0,78	disease	0,73	disease	0,72	4	neutral	0,88	neutral	0,24	NA	0	deleterious	0,59	low_impact	-1,57	medium_impact	0,1	medium_impact	1,22	0,75	0,85	8,79	11,75	N	0,31	N	0,49	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13908	13908	C	G	MI.22605	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1572	524	N	K	aaC/aaG	-1,21	0	0	possibly_damaging	0,88	neutral	0,36	neutral	0,92	neutral	-1,1	deleterious	-3,15	medium_impact	2,65	neutral	0,71	neutral	0,58	deleterious	2,53	19,66	0,62	0,65	neutral	0,35	disease	0,78	disease	0,73	disease	0,72	4	neutral	0,88	neutral	0,24	NA	0	deleterious	0,59	low_impact	-1,57	medium_impact	0,1	medium_impact	1,22	0,75	0,85	8,79	11,75	N	0,32	N	0,49	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13909	13909	A	C	MI.22606	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1573	525	M	L	Ata/Cta	-4,87	0	0	probably_damaging	0,98	neutral	0,71	neutral	1,05	neutral	0,5	neutral	-0,86	neutral_impact	0,56	neutral	0,85	neutral	0,99	neutral	1,72	14,53	0,39	0,5	neutral	0,32	disease	0,58	neutral	0,4	neutral	0,46	1	deleterious	0,98	neutral	0,37	neutral	-2	deleterious	0,63	low_impact	-2,35	medium_impact	0,45	medium_impact	-0,69	0,56	0,8	14,93	12,75	N	0,23	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13909	13909	A	T	MI.22607	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1573	525	M	L	Ata/Tta	-4,87	0	0	probably_damaging	0,98	neutral	0,71	neutral	1,05	neutral	0,5	neutral	-0,86	neutral_impact	0,56	neutral	0,85	neutral	0,99	neutral	1,8	14,97	0,39	0,5	neutral	0,32	disease	0,58	neutral	0,4	neutral	0,46	1	deleterious	0,98	neutral	0,37	neutral	-2	deleterious	0,63	low_impact	-2,35	medium_impact	0,45	medium_impact	-0,69	0,56	0,8	14,93	12,75	N	0,24	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13909	13909	A	G	MI.22608	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1573	525	M	V	Ata/Gta	-4,87	0	0	probably_damaging	0,99	neutral	0,52	neutral	0,95	neutral	-0,68	neutral	-2,13	medium_impact	2,61	neutral	0,77	neutral	0,69	deleterious	2,79	21,3	0,45	0,55	neutral	0,48	disease	0,76	disease	0,7	disease	0,75	5	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,7	low_impact	-2,64	medium_impact	0,25	medium_impact	1,18	0,57	0,8	14,93	12,75	N	0,24	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13910	13910	T	A	MI.22609	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1574	525	M	K	aTa/aAa	-4,19	0	0	probably_damaging	1	neutral	0,38	neutral	0,92	neutral	-1,28	deleterious	-3,47	medium_impact	2,15	neutral	0,74	neutral	0,63	deleterious	4,16	23,8	0,25	0,45	neutral	0,25	disease	0,87	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,12	medium_impact	0,76	0,5	0,8	14,93	12,75	N	0,34	N	0,9	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6085	6085	A	T	MI.2261	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	182	61	H	L	cAt/cTt	4,52	1	0	probably_damaging	1	deleterious	0,01	neutral	-1,18	deleterious	-12,95	deleterious	-7,01	high_impact	5,19	neutral	0,63	damaging	0,03	deleterious	3,76	23,4	0,22	0,55	disease	0,92	disease	0,92	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,58	medium_impact	-0,92	high_impact	3,69	0,33	0,9	2,92	6,76	P	0,54	P	0,92	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13910	13910	T	C	MI.22610	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1574	525	M	T	aTa/aCa	-4,19	0	0	probably_damaging	1	neutral	0,45	neutral	0,97	neutral	-0,43	deleterious	-3,04	low_impact	1,92	neutral	0,85	neutral	0,93	deleterious	3,1	22,5	0,37	0,5	neutral	0,47	disease	0,76	disease	0,51	disease	0,54	1	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,18	medium_impact	0,55	0,32	0,8	14,93	12,75	N	0,27	N	0,63	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13911	13911	A	T	MI.22611	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1575	525	M	I	atA/atT	-0,06	0	0	probably_damaging	0,99	neutral	0,42	neutral	0,93	neutral	-1,01	neutral	-1,92	medium_impact	2,06	neutral	0,74	neutral	0,77	deleterious	3,63	23,2	0,47	0,55	disease	0,64	disease	0,76	disease	0,68	disease	0,68	4	deleterious	0,99	neutral	0,22	deleterious	1	deleterious	0,77	low_impact	-2,64	medium_impact	0,16	medium_impact	0,68	0,64	0,8	14,93	12,75	N	0,29	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13911	13911	A	C	MI.22612	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1575	525	M	I	atA/atC	-0,06	0	0	probably_damaging	0,99	neutral	0,42	neutral	0,93	neutral	-1,01	neutral	-1,92	medium_impact	2,06	neutral	0,74	neutral	0,77	deleterious	3,56	23,1	0,47	0,55	disease	0,64	disease	0,76	disease	0,68	disease	0,68	4	deleterious	0,99	neutral	0,22	deleterious	1	deleterious	0,77	low_impact	-2,64	medium_impact	0,16	medium_impact	0,68	0,64	0,8	14,93	12,75	N	0,3	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13912	13912	C	G	MI.22613	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1576	526	L	V	Ctc/Gtc	-3,5	0	0	probably_damaging	1	neutral	0,53	neutral	0,65	neutral	-2,39	deleterious	-2,68	medium_impact	3,17	neutral	0,71	neutral	0,38	deleterious	3,6	23,2	0,46	0,55	disease	0,56	disease	0,65	disease	0,66	disease	0,61	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,26	medium_impact	1,69	0,68	0,85	18,74	7,03	N	0,22	N	0,81	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13912	13912	C	T	MI.22614	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1576	526	L	F	Ctc/Ttc	-3,5	0	0	probably_damaging	1	neutral	0,71	neutral	0,61	deleterious	-3,1	deleterious	-3,56	medium_impact	2,4	neutral	0,71	neutral	0,45	deleterious	4,16	23,8	0,38	0,5	disease	0,82	disease	0,76	disease	0,59	disease	0,67	3	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,45	medium_impact	0,99	0,68	0,85	18,74	7,03	N	0,19	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13912	13912	C	A	MI.22615	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1576	526	L	I	Ctc/Atc	-3,5	0	0	probably_damaging	1	neutral	0,42	neutral	0,64	neutral	-2,55	neutral	-1,79	medium_impact	2,83	neutral	0,71	neutral	0,58	deleterious	4,25	23,9	0,36	0,5	disease	0,73	disease	0,69	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,16	medium_impact	1,38	0,78	0,85	18,74	7,03	N	0,27	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13913	13913	T	G	MI.22616	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1577	526	L	R	cTc/cGc	-1,89	0	0	probably_damaging	1	neutral	0,41	neutral	0,57	deleterious	-4,37	deleterious	-5,37	high_impact	3,72	damaging	0,59	damaging	0,27	deleterious	4,37	24,1	0,2	0,45	neutral	0,32	disease	0,88	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,15	high_impact	2,2	0,7	0,85	18,74	7,03	N	0,35	N	1	polymorphism	0,93	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13913	13913	T	A	MI.22617	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1577	526	L	H	cTc/cAc	-1,89	0	0	probably_damaging	1	neutral	0,56	neutral	0,56	deleterious	-5,06	deleterious	-6,26	high_impact	3,72	neutral	0,67	neutral	0,42	deleterious	4,4	24,1	0,22	0,45	disease	0,76	disease	0,83	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,29	high_impact	2,2	0,62	0,8	18,74	7,03	N	0,3	N	0,97	polymorphism	0,96	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13913	13913	T	C	MI.22618	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1577	526	L	P	cTc/cCc	-1,89	0	0	probably_damaging	1	neutral	0,24	neutral	0,56	deleterious	-5,13	deleterious	-6,27	medium_impact	2,44	neutral	0,61	damaging	0,28	deleterious	4,13	23,8	0,15	0,4	disease	0,7	disease	0,82	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	-0,04	medium_impact	1,03	0,49	0,8	18,74	7,03	N	0,24	N	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13915	13915	G	C	MI.22619	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1579	527	G	R	Gga/Cga	-0,52	0,04	0	probably_damaging	1	neutral	0,35	neutral	0,82	neutral	-2,84	deleterious	-7,17	high_impact	3,56	damaging	0,43	damaging	0,07	deleterious	4,06	23,7	0,25	0,45	disease	0,62	disease	0,88	disease	0,73	disease	0,81	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	0,08	high_impact	2,05	0,81	0,85	28,86	7,22	N	0,4	N	1	disease_causing	0,64	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6085	6085	A	C	MI.2262	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	182	61	H	P	cAt/cCt	4,52	1	0	probably_damaging	1	deleterious	0	neutral	-1,16	deleterious	-10,44	deleterious	-6,38	high_impact	5,19	damaging	0,48	damaging	0,03	deleterious	3,24	22,8	0,21	0,55	disease	0,91	disease	0,89	disease	0,82	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,33	0,9	2,92	6,76	P	0,54	P	0,9	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13915	13915	G	T	MI.22620	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1579	527	G	W	Gga/Tga	-0,52	0,04	0	probably_damaging	1	neutral	0,19	neutral	1,22	neutral	1,14	deleterious	-7,17	medium_impact	2,58	damaging	0,53	damaging	0,07	deleterious	4,57	24,4	0,22	0,45	neutral	0,45	disease	0,85	disease	0,62	disease	0,57	1	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	-0,12	medium_impact	1,15	0,44	0,8	28,86	7,22	N	0,27	N	1	disease_causing	0,75	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13916	13916	G	C	MI.22621	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1580	527	G	A	gGa/gCa	2,69	0,97	0	probably_damaging	1	neutral	0,51	neutral	0,89	neutral	-1,09	deleterious	-5,38	low_impact	1,7	damaging	0,6	damaging	0,28	deleterious	3,31	22,9	0,39	0,5	disease	0,5	neutral	0,36	neutral	0,29	neutral	0,19	6	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,24	medium_impact	0,35	0,75	0,85	28,86	7,22	N	0,41	N	0,79	polymorphism	0,55	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13916	13916	G	T	MI.22622	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1580	527	G	V	gGa/gTa	2,69	0,97	0	probably_damaging	1	neutral	0,5	neutral	0,88	neutral	-1,18	deleterious	-8,06	medium_impact	3,21	damaging	0,45	damaging	0,08	deleterious	4	23,6	0,26	0,45	neutral	0,4	disease	0,85	disease	0,65	disease	0,74	5	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,23	medium_impact	1,73	0,6	0,8	28,86	7,22	N	0,39	N	0,98	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13916	13916	G	A	MI.22623	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1580	527	G	E	gGa/gAa	2,69	0,97	0	probably_damaging	1	neutral	0,28	neutral	0,82	neutral	-2,67	deleterious	-7,17	high_impact	3,56	damaging	0,46	damaging	0,08	deleterious	4,02	23,6	0,25	0,45	disease	0,78	disease	0,85	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,01	high_impact	2,05	0,72	0,85	28,86	7,22	N	0,42	N	1	disease_causing	0,68	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13918	13918	T	A	MI.22624	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1582	528	F	I	Ttc/Atc	-13,58	0	0	possibly_damaging	0,87	neutral	0,39	neutral	-0,27	deleterious	-6,98	deleterious	-4,33	medium_impact	2,64	neutral	0,69	neutral	0,61	deleterious	4,62	24,5	0,26	0,45	neutral	0,5	disease	0,84	disease	0,7	disease	0,77	5	neutral	0,87	neutral	0,26	NA	0	deleterious	0,79	low_impact	-1,53	medium_impact	0,13	medium_impact	1,21	0,66	0,8	7,13	10,57	N	0,31	N	0,67	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13918	13918	T	C	MI.22625	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1582	528	F	L	Ttc/Ctc	-13,58	0	0	possibly_damaging	0,62	neutral	0,66	neutral	-0,25	deleterious	-5,88	deleterious	-4,33	medium_impact	2,64	neutral	0,68	neutral	0,58	deleterious	4,29	24	0,32	0,5	neutral	0,37	disease	0,81	disease	0,67	disease	0,68	4	neutral	0,55	deleterious	0,52	NA	0	deleterious	0,75	medium_impact	-0,95	medium_impact	0,39	medium_impact	1,21	0,7	0,85	7,13	10,57	N	0,3	N	0,69	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13918	13918	T	G	MI.22626	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1582	528	F	V	Ttc/Gtc	-13,58	0	0	possibly_damaging	0,79	neutral	0,49	neutral	-0,26	deleterious	-6,83	deleterious	-4,7	medium_impact	2,64	neutral	0,65	neutral	0,59	deleterious	4,31	24	0,33	0,5	neutral	0,31	disease	0,88	disease	0,71	disease	0,79	6	neutral	0,77	neutral	0,35	NA	0	deleterious	0,74	low_impact	-1,29	medium_impact	0,22	medium_impact	1,21	0,59	0,8	7,13	10,57	N	0,32	N	0,75	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13919	13919	T	A	MI.22627	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1583	528	F	Y	tTc/tAc	7,27	0,95	0	benign	0,04	neutral	1	neutral	0	neutral	-2,76	neutral	0,99	neutral_impact	0,07	neutral	0,87	neutral	0,98	deleterious	1,91	15,68	0,4	0,5	neutral	0,22	neutral	0,22	neutral	0,3	neutral	0,36	3	neutral	0,04	deleterious	0,98	neutral	-6	deleterious	0,68	medium_impact	0,57	high_impact	1,89	low_impact	-1,14	0,66	0,8	7,13	10,57	N	0,48	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13919	13919	T	C	MI.22628	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1583	528	F	S	tTc/tCc	7,27	0,95	0	possibly_damaging	0,9	neutral	0,41	neutral	-0,27	deleterious	-7,3	deleterious	-5,59	medium_impact	3,19	neutral	0,75	neutral	0,82	deleterious	4,48	24,2	0,28	0,45	disease	0,6	disease	0,85	disease	0,7	disease	0,76	5	neutral	0,9	neutral	0,26	NA	0	deleterious	0,82	low_impact	-1,65	medium_impact	0,15	medium_impact	1,71	0,55	0,8	7,13	10,57	N	0,53	P	0,89	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13919	13919	T	G	MI.22629	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1583	528	F	C	tTc/tGc	7,27	0,95	0	probably_damaging	0,98	neutral	0,17	neutral	-0,28	deleterious	-8,92	deleterious	-5,59	medium_impact	3,19	neutral	0,61	neutral	0,46	deleterious	4,28	24	0,23	0,45	disease	0,8	disease	0,9	disease	0,72	disease	0,81	6	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,83	low_impact	-2,35	medium_impact	-0,15	medium_impact	1,71	0,43	0,8	7,13	10,57	N	0,47	N	0,9	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6086	6086	T	A	MI.2263	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	183	61	H	Q	caT/caA	7,07	1	0	probably_damaging	1	deleterious	0	neutral	-1,17	deleterious	-11,86	deleterious	-5,1	high_impact	4,84	neutral	0,61	damaging	0,03	deleterious	3,64	23,2	0,3	0,55	disease	0,83	disease	0,84	disease	0,72	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,4	0,9	2,92	6,76	P	0,62	P	0,83	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13920	13920	C	A	MI.22630	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1584	528	F	L	ttC/ttA	-0,29	0	0	possibly_damaging	0,62	neutral	0,66	neutral	-0,25	deleterious	-5,88	deleterious	-4,33	medium_impact	2,64	neutral	0,68	neutral	0,58	deleterious	4,75	24,7	0,32	0,5	neutral	0,37	disease	0,81	disease	0,67	disease	0,68	4	neutral	0,55	deleterious	0,52	NA	0	deleterious	0,75	medium_impact	-0,95	medium_impact	0,39	medium_impact	1,21	0,7	0,85	7,13	10,57	N	0,28	N	0,69	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13920	13920	C	G	MI.22631	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1584	528	F	L	ttC/ttG	-0,29	0	0	possibly_damaging	0,62	neutral	0,66	neutral	-0,25	deleterious	-5,88	deleterious	-4,33	medium_impact	2,64	neutral	0,68	neutral	0,58	deleterious	4,52	24,3	0,32	0,5	neutral	0,37	disease	0,81	disease	0,67	disease	0,68	4	neutral	0,55	deleterious	0,52	NA	0	deleterious	0,75	medium_impact	-0,95	medium_impact	0,39	medium_impact	1,21	0,7	0,85	7,13	10,57	N	0,28	N	0,69	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13921	13921	T	A	MI.22632	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1585	529	Y	N	Tac/Aac	-0,98	0	0	probably_damaging	0,98	neutral	0,3	neutral	0,89	deleterious	-3,48	deleterious	-6,04	medium_impact	2,13	neutral	0,74	neutral	0,76	deleterious	4,13	23,8	0,27	0,45	disease	0,74	disease	0,81	disease	0,66	disease	0,75	5	neutral	0,98	neutral	0,16	deleterious	1	deleterious	0,84	low_impact	-2,35	medium_impact	0,03	medium_impact	0,74	0,44	0,8	2,65	8,76	N	0,27	N	0,75	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13921	13921	T	G	MI.22633	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1585	529	Y	D	Tac/Gac	-0,98	0	0	probably_damaging	0,98	neutral	0,19	neutral	0,89	deleterious	-4,32	deleterious	-6,4	medium_impact	2,48	neutral	0,65	neutral	0,41	deleterious	4,04	23,7	0,21	0,45	disease	0,81	disease	0,84	disease	0,72	disease	0,81	6	deleterious	0,98	neutral	0,11	deleterious	1	deleterious	0,86	low_impact	-2,35	medium_impact	-0,12	medium_impact	1,06	0,39	0,8	2,65	8,76	N	0,26	N	0,86	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13921	13921	T	C	MI.22634	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1585	529	Y	H	Tac/Cac	-0,98	0	0	probably_damaging	0,98	neutral	0,5	neutral	0,89	deleterious	-3,47	deleterious	-3,52	medium_impact	2,48	neutral	0,75	neutral	0,51	deleterious	3,69	23,3	0,32	0,5	disease	0,78	disease	0,66	disease	0,65	disease	0,72	4	neutral	0,97	neutral	0,26	deleterious	1	deleterious	0,83	low_impact	-2,35	medium_impact	0,23	medium_impact	1,06	0,59	0,8	2,65	8,76	N	0,24	N	0,37	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13922	13922	A	T	MI.22635	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1586	529	Y	F	tAc/tTc	3,61	0,28	0	benign	0,04	neutral	0,82	neutral	1,25	neutral	1,73	neutral	0,49	neutral_impact	-1,19	neutral	0,84	neutral	0,98	neutral	1,39	12,76	0,41	0,5	neutral	0,24	neutral	0,1	neutral	0,3	neutral	0,23	5	neutral	0,11	deleterious	0,89	neutral	-6	deleterious	0,66	medium_impact	0,57	medium_impact	0,6	low_impact	-2,29	0,59	0,8	2,65	8,76	N	0,38	N	0,11	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13922	13922	A	G	MI.22636	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1586	529	Y	C	tAc/tGc	3,61	0,28	0	probably_damaging	0,98	neutral	0,16	neutral	0,89	deleterious	-3,53	deleterious	-5,61	medium_impact	2,13	neutral	0,61	neutral	0,48	deleterious	4,21	23,9	0,25	0,45	disease	0,77	disease	0,85	disease	0,69	disease	0,8	6	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,83	low_impact	-2,35	medium_impact	-0,17	medium_impact	0,74	0,28	0,8	2,65	8,76	N	0,3	N	0,77	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13922	13922	A	C	MI.22637	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1586	529	Y	S	tAc/tCc	3,61	0,28	0	probably_damaging	0,92	neutral	0,47	neutral	0,9	neutral	-2,35	deleterious	-5,54	low_impact	1,78	neutral	0,65	neutral	0,58	deleterious	4,35	24,1	0,2	0,45	disease	0,51	disease	0,73	disease	0,63	disease	0,72	4	neutral	0,92	neutral	0,28	neutral	-2	deleterious	0,79	low_impact	-1,75	medium_impact	0,2	medium_impact	0,42	0,54	0,8	2,65	8,76	N	0,28	N	0,74	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13924	13924	C	A	MI.22638	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1588	530	P	T	Cct/Act	-3,27	0	0	benign	0,12	neutral	0,46	neutral	0,68	neutral	-2,36	deleterious	-5,47	low_impact	1,1	neutral	0,85	neutral	0,81	deleterious	2,79	21,3	0,33	0,5	disease	0,51	disease	0,73	neutral	0,35	disease	0,54	1	neutral	0,46	deleterious	0,67	neutral	-6	deleterious	0,76	medium_impact	0,08	medium_impact	0,19	medium_impact	-0,2	0,79	0,85	21,23	16,42	N	0,3	N	0,52	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13924	13924	C	T	MI.22639	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1588	530	P	S	Cct/Tct	-3,27	0	0	benign	0,12	neutral	0,51	neutral	0,69	neutral	-2,23	deleterious	-5,5	low_impact	1,03	neutral	0,86	neutral	0,73	deleterious	2,9	21,9	0,37	0,5	neutral	0,42	disease	0,75	neutral	0,35	disease	0,54	1	neutral	0,4	deleterious	0,7	neutral	-6	deleterious	0,77	medium_impact	0,08	medium_impact	0,24	medium_impact	-0,26	0,42	0,8	21,23	16,42	N	0,25	N	0,36	polymorphism	1	0,1	rs200713907	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6086	6086	T	G	MI.2264	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	183	61	H	Q	caT/caG	7,07	1	0	probably_damaging	1	deleterious	0	neutral	-1,17	deleterious	-11,86	deleterious	-5,1	high_impact	4,84	neutral	0,61	damaging	0,03	deleterious	3,44	23	0,3	0,55	disease	0,83	disease	0,84	disease	0,72	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,4	0,9	2,92	6,76	P	0,61	P	0,83	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13924	13924	C	G	MI.22640	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1588	530	P	A	Cct/Gct	-3,27	0	0	possibly_damaging	0,62	neutral	0,59	neutral	0,67	neutral	-2,49	deleterious	-5,8	medium_impact	3,1	neutral	0,73	neutral	0,49	deleterious	3,22	22,7	0,27	0,45	neutral	0,43	disease	0,64	disease	0,61	disease	0,67	3	neutral	0,57	deleterious	0,49	NA	0	deleterious	0,74	medium_impact	-0,95	medium_impact	0,32	medium_impact	1,63	0,85	0,9	21,23	16,42	N	0,27	N	0,63	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13925	13925	C	G	MI.22641	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1589	530	P	R	cCt/cGt	1,31	0,22	0	probably_damaging	0,94	neutral	0,41	neutral	0,65	neutral	-2,98	deleterious	-6,77	medium_impact	3,1	neutral	0,72	neutral	0,34	deleterious	3,76	23,3	0,22	0,45	neutral	0,43	disease	0,89	disease	0,73	disease	0,8	6	neutral	0,93	neutral	0,24	deleterious	1	deleterious	0,8	low_impact	-1,88	medium_impact	0,15	medium_impact	1,63	0,7	0,85	21,23	16,42	N	0,26	N	0,94	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13925	13925	C	A	MI.22642	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1589	530	P	H	cCt/cAt	1,31	0,22	0	probably_damaging	0,98	neutral	0,55	neutral	0,62	deleterious	-4,07	deleterious	-6,84	medium_impact	2,76	neutral	0,74	neutral	0,38	deleterious	4,1	23,7	0,23	0,45	disease	0,65	disease	0,83	disease	0,72	disease	0,77	5	deleterious	0,98	neutral	0,29	deleterious	1	deleterious	0,82	low_impact	-2,35	medium_impact	0,28	medium_impact	1,32	0,75	0,85	21,23	16,42	N	0,22	N	0,91	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13925	13925	C	T	MI.22643	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1589	530	P	L	cCt/cTt	1,31	0,22	0	possibly_damaging	0,73	neutral	0,69	neutral	0,65	neutral	-2,89	deleterious	-7,6	medium_impact	3,1	neutral	0,8	neutral	0,4	deleterious	4,45	24,2	0,35	0,5	disease	0,55	disease	0,87	disease	0,6	disease	0,75	5	neutral	0,67	deleterious	0,48	NA	0	deleterious	0,8	low_impact	-1,16	medium_impact	0,42	medium_impact	1,63	0,8	0,85	21,23	16,42	N	0,23	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13927	13927	A	G	MI.22644	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1591	531	S	G	Agc/Ggc	-10,37	0	0	benign	0,11	neutral	0,34	neutral	0,9	neutral	-2,04	neutral	-2,42	low_impact	1,76	neutral	0,81	neutral	0,72	deleterious	1,89	15,52	0,38	0,5	disease	0,54	neutral	0,3	neutral	0,36	neutral	0,43	2	neutral	0,61	deleterious	0,62	neutral	-6	neutral	0,32	medium_impact	0,12	medium_impact	0,07	medium_impact	0,41	0,7	0,85	28,52	16,4	N	0,37	N	0,26	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13927	13927	A	T	MI.22645	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1591	531	S	C	Agc/Tgc	-10,37	0	0	possibly_damaging	0,76	neutral	0,17	neutral	0,87	deleterious	-3,83	neutral	-1,78	low_impact	1,76	neutral	0,72	neutral	0,4	deleterious	3,52	23,1	0,3	0,45	disease	0,86	disease	0,59	neutral	0,37	disease	0,56	1	neutral	0,88	neutral	0,21	neutral	-3	deleterious	0,72	low_impact	-1,22	medium_impact	-0,15	medium_impact	0,41	0,65	0,8	28,52	16,4	N	0,3	N	0,39	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13927	13927	A	C	MI.22646	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1591	531	S	R	Agc/Cgc	-10,37	0	0	benign	0,17	neutral	0,35	neutral	0,92	neutral	-1,29	neutral	-1,86	low_impact	1,42	neutral	0,81	neutral	0,64	deleterious	2,28	18	0,2	0,45	neutral	0,45	disease	0,65	neutral	0,49	neutral	0,49	0	neutral	0,58	deleterious	0,59	neutral	-6	deleterious	0,51	medium_impact	-0,09	medium_impact	0,08	medium_impact	0,09	0,73	0,85	28,52	16,4	N	0,31	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13928	13928	G	A	MI.22647	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1592	531	S	N	aGc/aAc	-4,19	0	0,35	benign	0	neutral	0,33	neutral	0,99	neutral	-0,12	neutral	-1,1	neutral_impact	0,26	neutral	0,82	neutral	0,85	deleterious	0,62	8,28	0,57	0,65	neutral	0,45	neutral	0,31	neutral	0,4	neutral	0,45	1	neutral	0,67	deleterious	0,67	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,06	medium_impact	-0,97	0,68	0,85	28,52	16,4	N	0,36	N	0	polymorphism	1	0,02	rs28359184	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13928	13928	G	T	MI.22648	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1592	531	S	I	aGc/aTc	-4,19	0	0,35	benign	0,01	neutral	0,4	neutral	0,94	neutral	-0,92	neutral	-1,19	neutral_impact	-0,03	neutral	0,88	neutral	1	deleterious	2,71	20,9	0,3	0,45	disease	0,62	neutral	0,49	neutral	0,25	disease	0,51	0	neutral	0,59	deleterious	0,7	neutral	-6	deleterious	0,63	medium_impact	1,15	medium_impact	0,14	low_impact	-1,23	0,78	0,85	28,52	16,4	N	0,32	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13928	13928	G	C	MI.22649	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1592	531	S	T	aGc/aCc	-4,19	0	0,35	benign	0,01	neutral	0,4	neutral	0,96	neutral	-0,45	neutral	1,36	neutral_impact	-0,7	neutral	0,92	neutral	0,99	neutral	-0,98	0,02	0,32	0,5	neutral	0,28	neutral	0,09	neutral	0,13	neutral	0,26	5	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,32	medium_impact	1,15	medium_impact	0,14	low_impact	-1,84	0,7	0,85	28,52	16,4	N	0,46	N	0	polymorphism	1	0	rs28359184	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6087	6087	G	A	MI.2265	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	184	62	A	T	Gca/Aca	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,9	neutral	-2,64	neutral	-2,46	high_impact	4,99	neutral	0,63	damaging	0,05	deleterious	4,12	23,8	0,34	0,55	disease	0,62	disease	0,86	disease	0,56	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,51	0,71	0,9	2,53	6,59	P	0,66	P	0,2	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13930	13930	A	C	MI.22650	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1594	532	I	L	Atc/Ctc	-9	0	0	benign	0,13	neutral	0,67	neutral	1,13	neutral	0,45	neutral	-1	neutral_impact	0,56	neutral	0,76	neutral	0,95	deleterious	0,81	9,54	0,47	0,55	neutral	0,33	neutral	0,34	neutral	0,28	neutral	0,47	1	neutral	0,22	deleterious	0,77	neutral	-6	neutral	0,24	medium_impact	0,04	medium_impact	0,4	medium_impact	-0,69	0,7	0,85	17,41	14,16	N	0,35	N	0,7	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13930	13930	A	G	MI.22651	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1594	532	I	V	Atc/Gtc	-9	0	0	benign	0,13	neutral	0,5	neutral	0,76	neutral	-1,23	neutral	-0,3	low_impact	1,52	neutral	0,78	neutral	0,98	deleterious	0,18	4,42	0,67	0,7	neutral	0,39	neutral	0,25	neutral	0,35	neutral	0,44	1	neutral	0,41	deleterious	0,69	neutral	-6	neutral	0,22	medium_impact	0,04	medium_impact	0,23	medium_impact	0,19	0,47	0,8	17,41	14,16	N	0,37	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13930	13930	A	T	MI.22652	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1594	532	I	F	Atc/Ttc	-9	0	0	possibly_damaging	0,73	neutral	0,72	neutral	0,61	deleterious	-3,37	deleterious	-2,5	medium_impact	3,13	neutral	0,79	neutral	0,54	deleterious	3,72	23,3	0,45	0,55	neutral	0,43	disease	0,74	disease	0,54	disease	0,63	3	neutral	0,68	deleterious	0,5	NA	0	deleterious	0,64	low_impact	-1,16	medium_impact	0,46	medium_impact	1,66	0,68	0,85	17,41	14,16	N	0,21	N	0,46	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13931	13931	T	G	MI.22653	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1595	532	I	S	aTc/aGc	-0,52	0	0	benign	0,27	neutral	0,42	neutral	0,58	deleterious	-4,31	deleterious	-2,97	medium_impact	3,13	neutral	0,74	neutral	0,42	deleterious	2,75	21,1	0,37	0,5	disease	0,7	disease	0,81	disease	0,6	disease	0,74	5	neutral	0,49	deleterious	0,58	neutral	-3	deleterious	0,54	medium_impact	-0,34	medium_impact	0,16	medium_impact	1,66	0,5	0,8	17,41	14,16	N	0,27	N	0,86	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13931	13931	T	A	MI.22654	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1595	532	I	N	aTc/aAc	-0,52	0	0	possibly_damaging	0,46	neutral	0,33	neutral	0,57	deleterious	-5,5	deleterious	-3,86	medium_impact	3,13	neutral	0,7	neutral	0,36	deleterious	4,25	23,9	0,34	0,5	disease	0,82	disease	0,82	disease	0,63	disease	0,77	5	neutral	0,63	neutral	0,44	NA	0	deleterious	0,73	medium_impact	-0,68	medium_impact	0,06	medium_impact	1,66	0,48	0,8	17,41	14,16	N	0,27	N	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13931	13931	T	C	MI.22655	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1595	532	I	T	aTc/aCc	-0,52	0	0	benign	0	neutral	0,4	neutral	0,62	deleterious	-3,01	neutral	-1,23	low_impact	0,81	neutral	0,86	neutral	0,99	deleterious	0,12	3,81	0,41	0,5	disease	0,66	neutral	0,49	neutral	0,36	disease	0,56	1	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,23	high_impact	2,1	medium_impact	0,14	medium_impact	-0,46	0,5	0,8	17,41	14,16	N	0,35	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13932	13932	C	A	MI.22656	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1596	532	I	M	atC/atA	1,08	0	0	possibly_damaging	0,86	neutral	0,25	neutral	0,62	neutral	-2,94	neutral	-1,63	low_impact	1,89	neutral	0,73	neutral	0,68	deleterious	3,81	23,4	0,53	0,6	disease	0,71	disease	0,5	neutral	0,36	disease	0,53	1	neutral	0,9	neutral	0,2	neutral	-3	deleterious	0,71	low_impact	-1,5	medium_impact	-0,03	medium_impact	0,52	0,76	0,85	17,41	14,16	N	0,37	N	0,67	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13932	13932	C	G	MI.22657	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1596	532	I	M	atC/atG	1,08	0	0	possibly_damaging	0,86	neutral	0,25	neutral	0,62	neutral	-2,94	neutral	-1,63	low_impact	1,89	neutral	0,73	neutral	0,68	deleterious	3,36	22,9	0,53	0,6	disease	0,71	disease	0,5	neutral	0,36	disease	0,53	1	neutral	0,9	neutral	0,2	neutral	-3	deleterious	0,71	low_impact	-1,5	medium_impact	-0,03	medium_impact	0,52	0,76	0,85	17,41	14,16	N	0,37	N	0,67	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13933	13933	A	G	MI.22658	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1597	533	T	A	Aca/Gca	-4,64	0	0,01	benign	0,02	neutral	0,51	neutral	0,93	neutral	-0,75	neutral	-0,48	low_impact	1,36	neutral	0,9	neutral	0,9	deleterious	0,64	8,42	0,49	0,55	neutral	0,39	neutral	0,27	neutral	0,34	neutral	0,45	1	neutral	0,47	deleterious	0,75	neutral	-6	neutral	0,19	medium_impact	0,86	medium_impact	0,24	medium_impact	0,04	0,62	0,8	27,69	17,48	N	0,31	N	0,21	polymorphism	1	0,01	rs879235634	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13933	13933	A	T	MI.22659	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1597	533	T	S	Aca/Tca	-4,64	0	0,01	benign	0,25	neutral	0,43	neutral	1,19	neutral	1,19	neutral	-0,77	low_impact	1,76	neutral	0,82	neutral	0,71	neutral	1,66	14,17	0,45	0,55	neutral	0,33	neutral	0,3	disease	0,57	neutral	0,49	0	neutral	0,48	deleterious	0,59	neutral	-6	neutral	0,32	medium_impact	-0,29	medium_impact	0,17	medium_impact	0,41	0,81	0,85	27,69	17,48	N	0,34	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6087	6087	G	T	MI.2266	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	184	62	A	S	Gca/Tca	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,74	neutral	-2,1	neutral	-1,78	high_impact	4,64	neutral	0,63	damaging	0,04	deleterious	3,57	23,1	0,3	0,55	disease	0,54	disease	0,86	neutral	0,45	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,19	0,75	0,9	2,53	6,59	N	0,45	N	0,64	disease_causing	0,99	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13933	13933	A	C	MI.22660	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1597	533	T	P	Aca/Cca	-4,64	0	0,01	possibly_damaging	0,72	neutral	0,23	neutral	0,85	deleterious	-3,35	neutral	-1,89	low_impact	1,22	neutral	0,69	neutral	0,65	deleterious	3,23	22,8	0,17	0,45	disease	0,77	disease	0,71	disease	0,69	disease	0,64	3	neutral	0,83	neutral	0,26	neutral	-3	deleterious	0,67	low_impact	-1,14	medium_impact	-0,06	medium_impact	-0,09	0,69	0,85	27,69	17,48	N	0,29	N	0,32	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13934	13934	C	A	MI.22661	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1598	533	T	K	aCa/aAa	0,4	0	0,01	possibly_damaging	0,44	neutral	0,32	neutral	0,87	neutral	-2,41	neutral	-1,44	medium_impact	2,11	neutral	0,77	neutral	0,53	deleterious	2,79	21,3	0,22	0,45	disease	0,58	disease	0,64	disease	0,69	disease	0,74	5	neutral	0,64	neutral	0,44	NA	0	deleterious	0,47	medium_impact	-0,65	medium_impact	0,05	medium_impact	0,73	0,74	0,85	27,69	17,48	N	0,28	N	0,28	polymorphism	1	0,03	rs193302971	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13934	13934	C	T	MI.22662	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1598	533	T	M	aCa/aTa	0,4	0	0,01	benign	0,08	neutral	0,26	neutral	0,9	neutral	-1,38	neutral	2,14	low_impact	0,81	neutral	0,88	neutral	0,99	deleterious	0,07	3,29	0,37	0,5	neutral	0,32	neutral	0,15	neutral	0,27	neutral	0,29	4	neutral	0,71	deleterious	0,59	neutral	-6	neutral	0,12	medium_impact	0,26	medium_impact	-0,02	medium_impact	-0,46	0,76	0,85	27,69	17,48	N	0,38	N	0	polymorphism	1	0,01	rs193302971	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13936	13936	C	A	MI.22663	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1600	534	H	N	Cac/Aac	-12,44	0	0	probably_damaging	1	neutral	0,31	neutral	0,67	neutral	-2,83	deleterious	-6,27	high_impact	3,56	damaging	0,52	damaging	0,14	deleterious	4,12	23,8	0,42	0,55	neutral	0,41	disease	0,79	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,04	high_impact	2,05	0,62	0,8	27,36	7,18	N	0,36	N	0,97	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13936	13936	C	T	MI.22664	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1600	534	H	Y	Cac/Tac	-12,44	0	0	probably_damaging	1	neutral	1	neutral	0,62	deleterious	-4,93	deleterious	-5,37	high_impact	3,9	damaging	0,54	damaging	0,11	deleterious	3,94	23,5	0,45	0,55	disease	0,82	disease	0,83	disease	0,79	disease	0,85	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,85	low_impact	-3,6	high_impact	1,89	high_impact	2,36	0,49	0,8	27,36	7,18	N	0,28	N	1	polymorphism	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13936	13936	C	G	MI.22665	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1600	534	H	D	Cac/Gac	-12,44	0	0	probably_damaging	1	neutral	0,2	neutral	0,66	deleterious	-3,15	deleterious	-8,06	high_impact	3,9	damaging	0,55	damaging	0,13	deleterious	4,05	23,7	0,2	0,45	neutral	0,43	disease	0,83	disease	0,84	disease	0,83	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	-0,1	high_impact	2,36	0,54	0,8	27,36	7,18	N	0,41	N	0,97	polymorphism	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13937	13937	A	G	MI.22666	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1601	534	H	R	cAc/cGc	5,44	1	0	probably_damaging	1	neutral	0,35	neutral	0,65	deleterious	-3,25	deleterious	-7,16	high_impact	3,9	damaging	0,55	damaging	0,13	deleterious	3,05	22,4	0,4	0,5	neutral	0,42	disease	0,86	disease	0,81	disease	0,82	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,08	high_impact	2,36	0,49	0,8	27,36	7,18	P	0,52	P	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13937	13937	A	T	MI.22667	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1601	534	H	L	cAc/cTc	5,44	1	0	probably_damaging	1	neutral	0,65	neutral	0,64	deleterious	-3,65	deleterious	-9,85	high_impact	3,9	damaging	0,46	damaging	0,11	deleterious	3,87	23,5	0,24	0,45	disease	0,57	disease	0,9	disease	0,78	disease	0,82	6	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,38	high_impact	2,36	0,37	0,8	27,36	7,18	P	0,61	P	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13937	13937	A	C	MI.22668	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1601	534	H	P	cAc/cCc	5,44	1	0	probably_damaging	1	neutral	0,2	neutral	0,63	deleterious	-4,39	deleterious	-8,96	medium_impact	3,36	damaging	0,49	damaging	0,14	deleterious	3,28	22,8	0,23	0,45	disease	0,7	disease	0,86	disease	0,84	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	-0,1	medium_impact	1,87	0,43	0,8	27,36	7,18	P	0,53	P	0,97	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13938	13938	C	A	MI.22669	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1602	534	H	Q	caC/caA	6,59	1	0	probably_damaging	1	neutral	0,29	neutral	0,66	deleterious	-3,09	deleterious	-7,16	high_impact	3,56	damaging	0,49	damaging	0,15	deleterious	4,05	23,7	0,39	0,5	disease	0,51	disease	0,77	disease	0,78	disease	0,75	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,02	high_impact	2,05	0,61	0,8	27,36	7,18	P	0,56	P	0,95	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6087	6087	G	C	MI.2267	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	184	62	A	P	Gca/Cca	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,73	deleterious	-3,83	deleterious	-3,06	high_impact	4,99	damaging	0,54	damaging	0,04	deleterious	3,72	23,3	0,13	0,55	neutral	0,28	disease	0,88	disease	0,68	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,51	0,74	0,9	2,53	6,59	P	0,61	P	0,85	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13938	13938	C	G	MI.22670	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1602	534	H	Q	caC/caG	6,59	1	0	probably_damaging	1	neutral	0,29	neutral	0,66	deleterious	-3,09	deleterious	-7,16	high_impact	3,56	damaging	0,49	damaging	0,15	deleterious	3,75	23,3	0,39	0,5	disease	0,51	disease	0,77	disease	0,78	disease	0,75	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	0,02	high_impact	2,05	0,61	0,8	27,36	7,18	P	0,56	P	0,95	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13939	13939	C	A	MI.22671	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1603	535	R	S	Cgc/Agc	-0,75	0,05	0	probably_damaging	1	neutral	0,41	neutral	0,86	neutral	-1,16	deleterious	-5,37	high_impact	3,88	damaging	0,44	damaging	0,08	deleterious	4,87	24,9	0,33	0,5	disease	0,61	disease	0,81	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,15	high_impact	2,34	0,45	0,8	28,52	7,13	N	0,43	N	0,82	disease_causing	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13939	13939	C	T	MI.22672	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1603	535	R	C	Cgc/Tgc	-0,75	0,05	0	probably_damaging	1	neutral	0,17	neutral	0,74	deleterious	-5,07	deleterious	-7,15	high_impact	3,88	damaging	0,49	damaging	0,05	deleterious	5,16	25,4	0,35	0,5	disease	0,94	disease	0,86	disease	0,75	disease	0,84	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,15	high_impact	2,34	0,75	0,85	28,52	7,13	N	0,35	N	1	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13939	13939	C	G	MI.22673	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1603	535	R	G	Cgc/Ggc	-0,75	0,05	0	probably_damaging	1	neutral	0,34	neutral	0,77	neutral	-2,74	deleterious	-6,26	high_impact	3,88	damaging	0,5	damaging	0,12	deleterious	4,35	24,1	0,26	0,45	disease	0,64	disease	0,78	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,07	high_impact	2,34	0,4	0,8	28,52	7,13	N	0,35	N	0,97	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13940	13940	G	T	MI.22674	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1604	535	R	L	cGc/cTc	2,69	0,98	0	probably_damaging	1	neutral	0,67	neutral	0,81	neutral	-1,77	deleterious	-6,26	high_impact	3,54	damaging	0,43	damaging	0,05	deleterious	4,5	24,3	0,42	0,55	disease	0,67	disease	0,92	disease	0,71	disease	0,8	6	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	0,4	high_impact	2,03	0,29	0,8	28,52	7,13	P	0,54	P	1	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13940	13940	G	C	MI.22675	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1604	535	R	P	cGc/cCc	2,69	0,98	0	probably_damaging	1	neutral	0,21	neutral	0,76	deleterious	-3,18	deleterious	-6,26	high_impact	3,54	damaging	0,45	damaging	0,06	deleterious	4,44	24,2	0,16	0,45	disease	0,74	disease	0,87	disease	0,83	disease	0,85	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,09	high_impact	2,03	0,32	0,8	28,52	7,13	P	0,52	P	0,99	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13940	13940	G	A	MI.22676	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1604	535	R	H	cGc/cAc	2,69	0,98	0	probably_damaging	1	neutral	0,54	neutral	0,77	neutral	-2,81	deleterious	-4,48	medium_impact	2,84	damaging	0,53	damaging	0,06	deleterious	4,56	24,4	0,38	0,5	disease	0,79	disease	0,79	disease	0,58	disease	0,61	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	0,27	medium_impact	1,39	0,86	0,9	28,52	7,13	N	0,38	N	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13942	13942	A	C	MI.22677	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1606	536	T	P	Aca/Cca	-8,31	0	0,02	benign	0,41	neutral	0,23	neutral	0,99	neutral	-0,28	neutral	-2,2	neutral_impact	0,7	neutral	0,71	neutral	0,77	deleterious	3,31	22,9	0,16	0,45	disease	0,63	disease	0,68	disease	0,58	disease	0,58	2	neutral	0,73	neutral	0,41	neutral	-6	deleterious	0,68	medium_impact	-0,6	medium_impact	-0,06	medium_impact	-0,56	0,66	0,8	23,55	18,53	N	0,31	N	0,33	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13942	13942	A	T	MI.22678	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1606	536	T	S	Aca/Tca	-8,31	0	0,02	benign	0,01	neutral	0,45	neutral	1,03	neutral	0,51	neutral	-0,67	neutral_impact	-0,04	neutral	0,88	neutral	0,97	deleterious	0,38	6,44	0,47	0,55	disease	0,51	neutral	0,2	neutral	0,17	neutral	0,29	4	neutral	0,54	deleterious	0,72	neutral	-6	neutral	0,17	medium_impact	1,15	medium_impact	0,18	low_impact	-1,24	0,68	0,85	23,55	18,53	N	0,46	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13942	13942	A	G	MI.22679	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1606	536	T	A	Aca/Gca	-8,31	0	0,02	benign	0,04	neutral	0,51	neutral	1,02	neutral	0,33	neutral	-0,58	neutral_impact	0,12	neutral	0,78	neutral	0,88	deleterious	0,66	8,57	0,63	0,7	neutral	0,45	neutral	0,19	neutral	0,32	neutral	0,38	2	neutral	0,44	deleterious	0,74	neutral	-6	neutral	0,25	medium_impact	0,57	medium_impact	0,24	low_impact	-1,09	0,42	0,8	23,55	18,53	N	0,26	N	0,14	polymorphism	1	0,01	rs200657506	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6088	6088	C	G	MI.2268	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	185	62	A	G	gCa/gGa	5,22	1	0	probably_damaging	0,99	neutral	0,11	neutral	3,11	neutral	2,96	neutral	-2,11	low_impact	1,88	neutral	0,6	damaging	0,06	deleterious	3,76	23,3	0,25	0,55	neutral	0,18	disease	0,71	neutral	0,32	neutral	0,5	0	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,73	low_impact	-2,64	medium_impact	-0,31	medium_impact	0,64	0,74	0,9	2,53	6,59	P	0,46	N	0,56	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13943	13943	C	T	MI.22680	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1607	536	T	M	aCa/aTa	-8,31	0	0	benign	0,01	neutral	0,24	neutral	1,02	neutral	0,39	neutral	1,01	neutral_impact	-0,3	neutral	0,86	neutral	0,85	neutral	1	10,66	0,4	0,5	disease	0,53	neutral	0,25	neutral	0,19	neutral	0,41	2	neutral	0,75	deleterious	0,62	neutral	-6	neutral	0,21	medium_impact	1,15	medium_impact	-0,04	low_impact	-1,48	0,79	0,85	23,55	18,53	N	0,43	N	0,01	polymorphism	1	0,01	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	13943	13943	C	A	MI.22681	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1607	536	T	K	aCa/aAa	-8,31	0	0	benign	0,11	neutral	0,31	neutral	0,97	neutral	-0,69	neutral	-1,49	neutral_impact	0,24	neutral	0,77	neutral	0,7	deleterious	2,85	21,6	0,31	0,5	disease	0,75	disease	0,51	disease	0,56	disease	0,66	3	neutral	0,64	deleterious	0,6	neutral	-6	deleterious	0,53	medium_impact	0,12	medium_impact	0,04	medium_impact	-0,98	0,74	0,85	23,55	18,53	N	0,28	N	0,37	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13945	13945	A	C	MI.22682	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1609	537	I	L	Atc/Ctc	-4,87	0	0	benign	0,17	neutral	0,68	neutral	1,02	neutral	0,12	neutral	0,2	neutral_impact	-0,25	neutral	0,79	neutral	0,98	neutral	-0,23	0,95	0,47	0,55	neutral	0,37	neutral	0,16	neutral	0,14	neutral	0,27	5	neutral	0,2	deleterious	0,76	neutral	-6	neutral	0,21	medium_impact	-0,09	medium_impact	0,41	low_impact	-1,43	0,73	0,85	31,51	21,31	N	0,39	N	0,35	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13945	13945	A	G	MI.22683	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1609	537	I	V	Atc/Gtc	-4,87	0	0	benign	0,01	neutral	0,51	neutral	1,01	neutral	0,04	neutral	0	low_impact	0,9	neutral	0,87	neutral	0,96	neutral	-0,58	0,14	0,62	0,65	neutral	0,44	neutral	0,11	neutral	0,2	neutral	0,31	4	neutral	0,47	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	1,15	medium_impact	0,24	medium_impact	-0,38	0,46	0,8	31,51	21,31	N	0,46	N	0,12	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13945	13945	A	T	MI.22684	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1609	537	I	F	Atc/Ttc	-4,87	0	0	possibly_damaging	0,83	neutral	0,71	neutral	0,88	neutral	-1,19	neutral	-0,96	low_impact	0,86	neutral	0,8	neutral	0,82	neutral	1,76	14,74	0,46	0,55	neutral	0,45	neutral	0,34	neutral	0,2	neutral	0,45	1	neutral	0,8	neutral	0,44	neutral	-3	deleterious	0,62	low_impact	-1,4	medium_impact	0,45	medium_impact	-0,42	0,75	0,85	31,51	21,31	N	0,28	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13946	13946	T	C	MI.22685	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1610	537	I	T	aTc/aCc	-9,69	0	0	benign	0,36	neutral	0,42	neutral	0,88	neutral	-1,13	neutral	-0,56	neutral_impact	0,43	neutral	0,81	neutral	0,99	neutral	1,37	12,62	0,39	0,5	neutral	0,47	neutral	0,13	neutral	0,23	neutral	0,26	5	neutral	0,51	deleterious	0,53	neutral	-6	deleterious	0,5	medium_impact	-0,51	medium_impact	0,16	medium_impact	-0,81	0,57	0,8	31,51	21,31	N	0,43	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13946	13946	T	G	MI.22686	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1610	537	I	S	aTc/aGc	-9,69	0	0	benign	0,36	neutral	0,44	neutral	0,85	neutral	-1,63	neutral	-0,73	low_impact	0,82	neutral	0,79	neutral	0,95	deleterious	2,5	19,45	0,33	0,5	disease	0,53	neutral	0,31	neutral	0,27	neutral	0,36	3	neutral	0,48	deleterious	0,54	neutral	-6	deleterious	0,63	medium_impact	-0,51	medium_impact	0,18	medium_impact	-0,45	0,56	0,8	31,51	21,31	N	0,39	N	0,36	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13946	13946	T	A	MI.22687	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1610	537	I	N	aTc/aAc	-9,69	0	0	benign	0,03	neutral	0,33	neutral	0,8	deleterious	-3,15	neutral	-1,49	low_impact	0,94	neutral	0,8	neutral	0,87	deleterious	3,11	22,5	0,28	0,45	disease	0,69	neutral	0,47	neutral	0,28	disease	0,5	0	neutral	0,65	deleterious	0,65	neutral	-6	deleterious	0,74	medium_impact	0,69	medium_impact	0,06	medium_impact	-0,34	0,54	0,8	31,51	21,31	N	0,34	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13947	13947	C	A	MI.22688	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1611	537	I	M	atC/atA	-1,89	0	0	possibly_damaging	0,87	neutral	0,23	neutral	0,91	neutral	-0,77	neutral	0,32	neutral_impact	0,74	neutral	0,79	neutral	0,97	deleterious	2,52	19,59	0,48	0,55	disease	0,57	neutral	0,12	neutral	0,18	neutral	0,33	3	neutral	0,91	neutral	0,18	neutral	-3	deleterious	0,63	low_impact	-1,53	medium_impact	-0,06	medium_impact	-0,53	0,76	0,85	31,51	21,31	P	0,56	P	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13947	13947	C	G	MI.22689	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1611	537	I	M	atC/atG	-1,89	0	0	possibly_damaging	0,87	neutral	0,23	neutral	0,91	neutral	-0,77	neutral	0,32	neutral_impact	0,74	neutral	0,79	neutral	0,97	deleterious	2,09	16,76	0,48	0,55	disease	0,57	neutral	0,12	neutral	0,18	neutral	0,33	3	neutral	0,91	neutral	0,18	neutral	-3	deleterious	0,63	low_impact	-1,53	medium_impact	-0,06	medium_impact	-0,53	0,76	0,85	31,51	21,31	P	0,56	P	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6088	6088	C	A	MI.2269	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	185	62	A	E	gCa/gAa	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,72	deleterious	-3,77	deleterious	-3,06	high_impact	4,99	damaging	0,6	damaging	0,05	deleterious	4,31	24	0,11	0,55	disease	0,81	disease	0,92	disease	0,66	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,51	0,71	0,9	2,53	6,59	P	0,75	P	0,76	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13948	13948	C	A	MI.22690	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1612	538	P	T	Ccc/Acc	-11,75	0	0	probably_damaging	1	neutral	0,42	neutral	0,9	neutral	-1,25	deleterious	-6,52	low_impact	1,49	neutral	0,82	neutral	0,94	deleterious	3,8	23,4	0,37	0,5	neutral	0,44	disease	0,6	disease	0,54	neutral	0,46	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	0,16	medium_impact	0,16	0,8	0,85	4,48	8,3	N	0,33	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13948	13948	C	G	MI.22691	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1612	538	P	A	Ccc/Gcc	-11,75	0	0	probably_damaging	1	neutral	0,54	neutral	0,92	neutral	-0,84	deleterious	-6,71	medium_impact	2,69	neutral	0,76	neutral	0,67	deleterious	3,27	22,8	0,39	0,5	neutral	0,47	disease	0,5	disease	0,66	disease	0,59	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,27	medium_impact	1,25	0,84	0,9	4,48	8,3	N	0,33	N	0,73	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13948	13948	C	T	MI.22692	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1612	538	P	S	Ccc/Tcc	-11,75	0	0	probably_damaging	1	neutral	0,44	neutral	1,05	neutral	0,35	deleterious	-6,63	low_impact	1,57	neutral	0,83	neutral	0,96	deleterious	4,03	23,7	0,49	0,55	disease	0,51	disease	0,54	neutral	0,39	neutral	0,47	1	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,18	medium_impact	0,23	0,33	0,8	4,48	8,3	N	0,34	N	0,78	polymorphism	1	0,09	rs878869470	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13949	13949	C	T	MI.22693	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1613	538	P	L	cCc/cTc	-0,29	0	0	probably_damaging	1	neutral	0,66	neutral	0,92	neutral	-0,89	deleterious	-8,47	high_impact	3,58	neutral	0,7	neutral	0,46	deleterious	4,61	24,4	0,44	0,55	disease	0,53	disease	0,79	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,39	high_impact	2,07	0,86	0,9	4,48	8,3	N	0,29	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13949	13949	C	A	MI.22694	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1613	538	P	H	cCc/cAc	-0,29	0	0	probably_damaging	1	neutral	0,54	neutral	0,84	neutral	-2,97	deleterious	-7,56	high_impact	3,58	neutral	0,7	neutral	0,43	deleterious	4,24	23,9	0,28	0,45	disease	0,75	disease	0,77	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,27	high_impact	2,07	0,73	0,85	4,48	8,3	N	0,3	N	0,72	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13949	13949	C	G	MI.22695	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1613	538	P	R	cCc/cGc	-0,29	0	0	probably_damaging	1	neutral	0,37	neutral	0,86	neutral	-1,99	deleterious	-7,62	high_impact	3,58	neutral	0,68	neutral	0,39	deleterious	3,79	23,4	0,26	0,45	disease	0,61	disease	0,81	disease	0,78	disease	0,77	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,11	high_impact	2,07	0,74	0,85	4,48	8,3	N	0,38	N	0,64	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13951	13951	T	A	MI.22696	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1615	539	Y	N	Tat/Aat	-13,35	0	0	possibly_damaging	0,48	neutral	0,34	neutral	1,02	neutral	0,32	neutral	-2,36	neutral_impact	0,04	neutral	0,83	neutral	0,89	deleterious	2,45	19,11	0,45	0,55	neutral	0,39	neutral	0,43	neutral	0,28	neutral	0,49	0	neutral	0,63	neutral	0,43	neutral	-3	deleterious	0,58	medium_impact	-0,71	medium_impact	0,07	low_impact	-1,17	0,26	0,8	27,53	17,09	N	0,35	N	0,68	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13951	13951	T	C	MI.22697	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1615	539	Y	H	Tat/Cat	-13,35	0	0	benign	0,01	neutral	0,54	neutral	0,96	neutral	-1,17	neutral	-0,61	neutral_impact	-0,33	neutral	0,84	neutral	0,97	neutral	-0,15	1,38	0,55	0,6	disease	0,52	neutral	0,3	neutral	0,23	neutral	0,38	2	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,2	medium_impact	1,15	medium_impact	0,27	low_impact	-1,5	0,21	0,8	27,53	17,09	N	0,34	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13951	13951	T	G	MI.22698	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1615	539	Y	D	Tat/Gat	-13,35	0	0	possibly_damaging	0,69	neutral	0,19	neutral	0,98	neutral	-0,53	deleterious	-3,58	neutral_impact	0,77	neutral	0,82	neutral	0,79	deleterious	2,78	21,3	0,39	0,5	neutral	0,45	disease	0,57	neutral	0,48	neutral	0,49	0	neutral	0,84	neutral	0,25	neutral	-3	deleterious	0,68	low_impact	-1,08	medium_impact	-0,12	medium_impact	-0,5	0,31	0,8	27,53	17,09	N	0,35	N	0,73	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13952	13952	A	C	MI.22699	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1616	539	Y	S	tAt/tCt	-3,04	0	0	benign	0,04	neutral	0,51	neutral	1,05	neutral	0,77	deleterious	-2,68	neutral_impact	0	neutral	0,85	neutral	0,95	deleterious	2,13	17,03	0,31	0,45	neutral	0,27	neutral	0,34	neutral	0,29	neutral	0,46	1	neutral	0,44	deleterious	0,74	neutral	-6	deleterious	0,58	medium_impact	0,57	medium_impact	0,24	low_impact	-1,2	0,27	0,8	27,53	17,09	N	0,31	N	0,65	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8633	8633	A	G	MI.227	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	107	36	Y	C	tAt/tGt	2,9	0,2	0	possibly_damaging	0,65	neutral	0,15	neutral	4,38	neutral	-1,34	neutral	-2,27	low_impact	1,75	neutral	0,82	neutral	0,38	deleterious	3,09	22,5	0,45	0,65	disease	0,86	disease	0,59	disease	0,53	disease	0,66	3	neutral	0,86	neutral	0,25	neutral	-3	deleterious	0,65	low_impact	-1,01	medium_impact	-0,13	medium_impact	0,4	0,14	0,9	29,2	23,72	N	0,28	N	0,52	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6088	6088	C	T	MI.2270	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	185	62	A	V	gCa/gTa	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,85	deleterious	-3,66	deleterious	-2,51	high_impact	4,43	neutral	0,6	damaging	0,03	deleterious	4,3	24	0,36	0,55	disease	0,75	disease	0,91	disease	0,57	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,99	0,76	0,9	2,53	6,59	P	0,55	P	0,75	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13952	13952	A	G	MI.22700	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1616	539	Y	C	tAt/tGt	-3,04	0	0	benign	0,06	neutral	0,16	neutral	0,93	deleterious	-3,1	deleterious	-3,76	low_impact	1,32	neutral	0,77	neutral	0,41	deleterious	2,47	19,26	0,35	0,5	disease	0,86	disease	0,57	disease	0,53	disease	0,68	4	neutral	0,83	deleterious	0,55	neutral	-6	deleterious	0,75	medium_impact	0,39	medium_impact	-0,17	medium_impact	0	0,12	0,8	27,53	17,09	N	0,31	N	0,63	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13952	13952	A	T	MI.22701	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1616	539	Y	F	tAt/tTt	-3,04	0	0	possibly_damaging	0,64	neutral	0,74	neutral	0,97	neutral	-0,88	neutral	-1,59	low_impact	0,97	neutral	0,8	neutral	0,9	neutral	1,39	12,76	0,47	0,55	disease	0,5	neutral	0,32	neutral	0,33	neutral	0,26	5	neutral	0,56	deleterious	0,55	neutral	-3	deleterious	0,6	medium_impact	-0,98	medium_impact	0,48	medium_impact	-0,32	0,28	0,8	27,53	17,09	N	0,23	N	0,32	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13954	13954	C	A	MI.22702	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1618	540	L	M	Cta/Ata	-3,73	0	0	possibly_damaging	0,86	neutral	0,31	neutral	0,84	neutral	-1,74	neutral	-0,06	neutral_impact	0,69	neutral	0,84	neutral	0,99	deleterious	2,42	18,95	0,38	0,5	disease	0,58	neutral	0,08	neutral	0,13	neutral	0,36	3	neutral	0,88	neutral	0,23	neutral	-3	deleterious	0,63	low_impact	-1,5	medium_impact	0,04	medium_impact	-0,57	0,69	0,85	33	21,8	P	0,55	P	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13954	13954	C	G	MI.22703	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1618	540	L	V	Cta/Gta	-3,73	0	0	benign	0,27	neutral	0,5	neutral	0,91	neutral	-0,79	neutral	-0,8	medium_impact	2,16	neutral	0,86	neutral	0,94	deleterious	0,67	8,63	0,38	0,5	neutral	0,42	neutral	0,2	neutral	0,31	neutral	0,4	2	neutral	0,4	deleterious	0,62	neutral	-3	neutral	0,4	medium_impact	-0,34	medium_impact	0,23	medium_impact	0,77	0,4	0,8	33	21,8	N	0,39	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13955	13955	T	A	MI.22704	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1619	540	L	Q	cTa/cAa	-4,64	0	0	benign	0,02	neutral	0,3	neutral	0,8	neutral	-2,94	neutral	-1,13	neutral_impact	0,71	neutral	0,81	neutral	0,75	deleterious	2,94	22	0,29	0,45	disease	0,63	neutral	0,44	neutral	0,23	disease	0,58	2	neutral	0,69	deleterious	0,64	neutral	-6	deleterious	0,69	medium_impact	0,86	medium_impact	0,03	medium_impact	-0,55	0,51	0,8	33	21,8	N	0,35	N	0,08	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13955	13955	T	C	MI.22705	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1619	540	L	P	cTa/cCa	-4,64	0	0	possibly_damaging	0,54	neutral	0,2	neutral	0,79	deleterious	-3,15	neutral	-2,3	medium_impact	2,16	neutral	0,74	neutral	0,44	deleterious	3,92	23,5	0,2	0,45	neutral	0,43	disease	0,7	disease	0,53	disease	0,62	2	neutral	0,79	neutral	0,33	NA	0	deleterious	0,71	medium_impact	-0,81	medium_impact	-0,1	medium_impact	0,77	0,46	0,8	33	21,8	N	0,34	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13955	13955	T	G	MI.22706	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1619	540	L	R	cTa/cGa	-4,64	0	0	benign	0,37	neutral	0,34	neutral	0,81	neutral	-2,51	neutral	-1,27	medium_impact	2,5	neutral	0,73	neutral	0,65	deleterious	4,18	23,8	0,27	0,45	disease	0,55	disease	0,6	disease	0,53	disease	0,6	2	neutral	0,6	deleterious	0,49	neutral	-3	deleterious	0,69	medium_impact	-0,53	medium_impact	0,07	medium_impact	1,08	0,44	0,8	33	21,8	N	0,31	N	0,27	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13957	13957	G	C	MI.22707	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1621	541	G	R	Ggc/Cgc	-2,12	0	0	possibly_damaging	0,46	neutral	0,35	neutral	0,99	neutral	-0,25	neutral	-0,32	low_impact	0,8	neutral	0,77	neutral	0,44	deleterious	3,88	23,5	0,31	0,45	neutral	0,47	disease	0,58	disease	0,53	disease	0,62	2	neutral	0,61	neutral	0,45	neutral	-3	deleterious	0,69	medium_impact	-0,68	medium_impact	0,08	medium_impact	-0,47	0,89	0,9	15,42	10,94	N	0,29	N	0,22	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13957	13957	G	T	MI.22708	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1621	541	G	C	Ggc/Tgc	-2,12	0	0	probably_damaging	0,93	neutral	0,18	neutral	0,96	neutral	-2,19	neutral	-1,39	low_impact	0,8	neutral	0,78	neutral	0,46	deleterious	4,23	23,9	0,26	0,45	disease	0,8	disease	0,56	neutral	0,24	disease	0,55	1	neutral	0,96	neutral	0,13	neutral	-2	deleterious	0,75	low_impact	-1,81	medium_impact	-0,13	medium_impact	-0,47	0,72	0,85	15,42	10,94	N	0,32	N	0,52	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13957	13957	G	A	MI.22709	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1621	541	G	S	Ggc/Agc	-2,12	0	0	benign	0,02	neutral	0,42	neutral	1,16	neutral	2,02	neutral	1,47	neutral_impact	-1,17	neutral	0,88	neutral	0,98	deleterious	0,78	9,36	0,43	0,55	neutral	0,33	neutral	0,13	neutral	0,11	neutral	0,25	5	neutral	0,56	deleterious	0,7	neutral	-6	neutral	0,13	medium_impact	0,86	medium_impact	0,16	low_impact	-2,27	0,79	0,85	15,42	10,94	N	0,51	P	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6090	6090	T	G	MI.2271	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	187	63	F	V	Ttt/Gtt	-8,2	0	0	probably_damaging	1	deleterious	0	neutral	2,93	neutral	1,59	deleterious	-3,64	medium_impact	2,86	neutral	0,61	neutral	0,56	deleterious	3,94	23,5	0,27	0,55	neutral	0,24	disease	0,9	neutral	0,41	disease	0,55	1	deleterious	1	neutral	0	deleterious	5	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	medium_impact	1,54	0,55	0,9	1,95	6,88	N	0,4	N	0,84	polymorphism	0,78	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13958	13958	G	T	MI.22710	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1622	541	G	V	gGc/gTc	-0,29	0	0	possibly_damaging	0,46	neutral	0,51	neutral	1,04	neutral	0,82	neutral	-1,32	neutral_impact	-0,17	neutral	0,85	neutral	0,9	deleterious	3,65	23,2	0,25	0,45	neutral	0,28	neutral	0,38	neutral	0,33	neutral	0,45	1	neutral	0,46	deleterious	0,53	neutral	-3	deleterious	0,58	medium_impact	-0,68	medium_impact	0,24	low_impact	-1,36	0,62	0,8	15,42	10,94	N	0,3	N	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13958	13958	G	A	MI.22711	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1622	541	G	D	gGc/gAc	-0,29	0	0	benign	0,27	neutral	0,21	neutral	0,98	neutral	-0,55	neutral	0,23	low_impact	0,8	neutral	0,83	neutral	0,77	deleterious	3,67	23,2	0,21	0,45	disease	0,57	disease	0,55	neutral	0,48	neutral	0,49	0	neutral	0,75	deleterious	0,47	neutral	-6	deleterious	0,62	medium_impact	-0,34	medium_impact	-0,09	medium_impact	-0,47	0,44	0,8	15,42	10,94	N	0,4	N	0,15	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13958	13958	G	C	MI.22712	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1622	541	G	A	gGc/gCc	-0,29	0	0	benign	0,18	neutral	0,51	neutral	1,03	neutral	0,63	neutral	-0,22	neutral_impact	-0,4	neutral	0,87	neutral	0,87	neutral	1,54	13,51	0,47	0,55	neutral	0,33	neutral	0,17	neutral	0,26	neutral	0,31	4	neutral	0,39	deleterious	0,67	neutral	-6	neutral	0,38	medium_impact	-0,12	medium_impact	0,24	low_impact	-1,57	0,76	0,85	15,42	10,94	N	0,32	N	0,19	polymorphism	1	0	rs202081448	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13960	13960	C	A	MI.22713	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1624	542	L	I	Ctt/Att	-4,42	0	0	probably_damaging	1	neutral	0,44	neutral	0,03	deleterious	-3,9	neutral	-1,77	high_impact	3,77	damaging	0,54	damaging	0,09	deleterious	4,32	24	0,42	0,55	disease	0,76	neutral	0,48	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,18	high_impact	2,24	0,68	0,85	9,78	7,01	N	0,28	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13960	13960	C	T	MI.22714	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1624	542	L	F	Ctt/Ttt	-4,42	0	0	probably_damaging	1	neutral	0,71	neutral	0,02	deleterious	-4,08	deleterious	-3,53	medium_impact	2,19	damaging	0,54	damaging	0,08	deleterious	4,15	23,8	0,42	0,55	disease	0,68	disease	0,52	disease	0,55	neutral	0,49	0	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,45	medium_impact	0,8	0,63	0,8	9,78	7,01	N	0,19	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13960	13960	C	G	MI.22715	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1624	542	L	V	Ctt/Gtt	-4,42	0	0	probably_damaging	1	neutral	0,53	neutral	0,03	deleterious	-3,89	deleterious	-2,65	high_impact	3,77	damaging	0,49	damaging	0,07	deleterious	3,64	23,2	0,4	0,5	disease	0,64	neutral	0,48	disease	0,69	disease	0,63	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,76	low_impact	-3,6	medium_impact	0,26	high_impact	2,24	0,62	0,8	9,78	7,01	N	0,28	N	0,81	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13961	13961	T	A	MI.22716	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1625	542	L	H	cTt/cAt	-0,52	0	0	probably_damaging	1	neutral	0,56	neutral	-0,06	deleterious	-7,34	deleterious	-6,17	high_impact	3,77	damaging	0,53	damaging	0,09	deleterious	4,26	23,9	0,16	0,45	disease	0,61	disease	0,75	disease	0,78	disease	0,76	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,29	high_impact	2,24	0,53	0,8	9,78	7,01	N	0,33	N	0,97	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13961	13961	T	C	MI.22717	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1625	542	L	P	cTt/cCt	-0,52	0	0	probably_damaging	1	neutral	0,21	neutral	-0,06	deleterious	-7,28	deleterious	-6,18	high_impact	3,77	damaging	0,49	damaging	0,06	deleterious	3,99	23,6	0,14	0,4	disease	0,83	disease	0,76	disease	0,81	disease	0,83	7	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,09	high_impact	2,24	0,42	0,8	9,78	7,01	N	0,36	N	0,99	polymorphism	0,9	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13961	13961	T	G	MI.22718	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1625	542	L	R	cTt/cGt	-0,52	0	0	probably_damaging	1	neutral	0,43	neutral	-0,05	deleterious	-6,74	deleterious	-5,3	high_impact	3,77	damaging	0,49	damaging	0,07	deleterious	4,37	24,1	0,12	0,4	neutral	0,4	disease	0,81	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,17	high_impact	2,24	0,63	0,8	9,78	7,01	N	0,38	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13963	13963	C	G	MI.22719	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1627	543	L	V	Ctt/Gtt	-1,89	0	0	benign	0,04	neutral	0,5	neutral	1	neutral	-0,03	neutral	-0,4	neutral_impact	0,64	neutral	0,83	neutral	0,83	deleterious	0,3	5,66	0,53	0,6	neutral	0,45	neutral	0,11	neutral	0,28	neutral	0,29	4	neutral	0,46	deleterious	0,73	neutral	-6	neutral	0,24	medium_impact	0,57	medium_impact	0,23	medium_impact	-0,62	0,41	0,8	32,01	17,13	N	0,39	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6090	6090	T	C	MI.2272	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	187	63	F	L	Ttt/Ctt	-8,2	0	0	probably_damaging	0,99	neutral	0,19	neutral	2,95	neutral	1,58	deleterious	-2,79	low_impact	1,23	damaging	0,56	neutral	0,64	deleterious	2,77	21,2	0,44	0,55	neutral	0,18	disease	0,61	neutral	0,34	neutral	0,4	2	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,68	low_impact	-2,64	medium_impact	-0,16	medium_impact	0,04	0,6	0,9	1,95	6,88	N	0,42	N	0,83	polymorphism	0,87	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13963	13963	C	A	MI.22720	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1627	543	L	I	Ctt/Att	-1,89	0	0	benign	0,03	neutral	0,5	neutral	0,98	neutral	-0,2	neutral	-0,49	neutral_impact	-0,14	neutral	0,84	neutral	0,92	deleterious	0,69	8,74	0,42	0,5	disease	0,66	neutral	0,1	neutral	0,15	neutral	0,38	2	neutral	0,47	deleterious	0,74	neutral	-6	neutral	0,16	medium_impact	0,69	medium_impact	0,23	low_impact	-1,33	0,58	0,8	32,01	17,13	N	0,39	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13963	13963	C	T	MI.22721	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1627	543	L	F	Ctt/Ttt	-1,89	0	0	possibly_damaging	0,69	neutral	0,7	neutral	0,93	neutral	-1,22	neutral	-1,21	neutral_impact	-0,14	neutral	0,84	neutral	0,83	deleterious	2,54	19,73	0,47	0,55	disease	0,71	neutral	0,2	neutral	0,16	neutral	0,45	1	neutral	0,62	deleterious	0,51	neutral	-3	deleterious	0,65	low_impact	-1,08	medium_impact	0,44	low_impact	-1,33	0,54	0,8	32,01	17,13	N	0,32	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13964	13964	T	A	MI.22722	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1628	543	L	H	cTt/cAt	-4,87	0	0	probably_damaging	0,95	neutral	0,5	neutral	0,91	neutral	-1,89	neutral	-1,06	neutral_impact	0,12	neutral	0,83	neutral	0,91	deleterious	2,7	20,8	0,27	0,45	neutral	0,48	neutral	0,35	neutral	0,25	neutral	0,41	2	neutral	0,95	neutral	0,28	neutral	-2	deleterious	0,68	low_impact	-1,96	medium_impact	0,23	low_impact	-1,09	0,46	0,8	32,01	17,13	N	0,32	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13964	13964	T	C	MI.22723	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1628	543	L	P	cTt/cCt	-4,87	0	0	possibly_damaging	0,87	neutral	0,22	neutral	0,9	neutral	-2,6	neutral	-1,43	low_impact	1,45	neutral	0,63	neutral	0,42	deleterious	2,79	21,3	0,24	0,45	disease	0,55	disease	0,66	disease	0,52	disease	0,61	2	neutral	0,91	neutral	0,18	neutral	-3	deleterious	0,75	low_impact	-1,53	medium_impact	-0,07	medium_impact	0,12	0,37	0,8	32,01	17,13	N	0,31	N	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13964	13964	T	G	MI.22724	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1628	543	L	R	cTt/cGt	-4,87	0	0	possibly_damaging	0,83	neutral	0,32	neutral	0,92	neutral	-1,41	neutral	-0,62	neutral_impact	0,12	neutral	0,77	neutral	0,66	deleterious	3,07	22,4	0,3	0,45	neutral	0,44	disease	0,53	neutral	0,49	neutral	0,5	0	neutral	0,85	neutral	0,25	neutral	-3	deleterious	0,68	low_impact	-1,4	medium_impact	0,05	low_impact	-1,09	0,57	0,8	32,01	17,13	N	0,29	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13966	13966	A	T	MI.22725	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1630	544	T	S	Acg/Tcg	-5,79	0	0,05	benign	0,27	neutral	0,47	neutral	0,96	neutral	-0,61	neutral	-0,82	neutral_impact	0,7	neutral	0,84	neutral	0,83	deleterious	0,45	7,04	0,46	0,55	neutral	0,35	neutral	0,13	neutral	0,39	neutral	0,31	4	neutral	0,43	deleterious	0,6	neutral	-6	neutral	0,19	medium_impact	-0,34	medium_impact	0,2	medium_impact	-0,56	0,39	0,8	15,75	12,07	N	0,39	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13966	13966	A	C	MI.22726	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1630	544	T	P	Acg/Ccg	-5,79	0	0,05	possibly_damaging	0,66	neutral	0,23	neutral	0,9	neutral	-2,85	neutral	-2,24	medium_impact	2,19	neutral	0,76	neutral	0,51	deleterious	2,08	16,7	0,21	0,45	disease	0,82	disease	0,65	disease	0,66	disease	0,74	5	neutral	0,8	neutral	0,29	NA	0	deleterious	0,61	low_impact	-1,02	medium_impact	-0,06	medium_impact	0,8	0,47	0,8	15,75	12,07	N	0,28	N	0,37	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13966	13966	A	G	MI.22727	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1630	544	T	A	Acg/Gcg	-5,79	0	0,05	benign	0,01	neutral	0,56	neutral	0,96	neutral	-0,59	neutral	-0,76	low_impact	1,09	neutral	0,91	neutral	0,94	deleterious	0,51	7,54	0,61	0,65	neutral	0,34	neutral	0,15	neutral	0,4	neutral	0,31	4	neutral	0,43	deleterious	0,78	neutral	-6	neutral	0,12	medium_impact	1,15	medium_impact	0,29	medium_impact	-0,21	0,27	0,8	15,75	12,07	N	0,31	N	0,19	polymorphism	1	0,01	rs41535848	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13967	13967	C	A	MI.22728	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1631	544	T	K	aCg/aAg	-4,42	0	0	possibly_damaging	0,46	neutral	0,36	neutral	0,91	neutral	-1,88	neutral	-1,78	low_impact	1,16	neutral	0,82	neutral	0,76	deleterious	2,76	21,1	0,27	0,45	disease	0,75	neutral	0,43	disease	0,64	disease	0,66	3	neutral	0,6	neutral	0,45	neutral	-3	neutral	0,42	medium_impact	-0,68	medium_impact	0,1	medium_impact	-0,14	0,46	0,8	15,75	12,07	N	0,33	N	0,4	polymorphism	1	0,02	rs386829197	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13967	13967	C	T	MI.22729	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1631	544	T	M	aCg/aTg	-4,42	0	0	benign	0,03	neutral	0,25	neutral	0,99	neutral	-0,07	neutral	0,85	neutral_impact	-0,04	neutral	0,89	neutral	0,98	neutral	-0,18	1,23	0,35	0,5	neutral	0,43	neutral	0,11	neutral	0,2	neutral	0,32	4	neutral	0,74	deleterious	0,61	neutral	-6	neutral	0,12	medium_impact	0,69	medium_impact	-0,03	low_impact	-1,24	0,52	0,8	15,75	12,07	N	0,52	P	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	C13967T	Possible LHON factor	+	-	Reported	3
chrM	6090	6090	T	A	MI.2273	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	187	63	F	I	Ttt/Att	-8,2	0	0	probably_damaging	0,99	neutral	0,28	neutral	2,9	neutral	0,97	deleterious	-3	medium_impact	2,88	neutral	0,66	neutral	0,66	deleterious	4,25	23,9	0,31	0,55	neutral	0,18	disease	0,87	neutral	0,38	disease	0,53	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,73	low_impact	-2,64	medium_impact	-0,04	medium_impact	1,56	0,57	0,9	1,95	6,88	N	0,43	N	0,88	polymorphism	0,88	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13969	13969	A	T	MI.22730	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1633	545	S	C	Agc/Tgc	-5,33	0	0	probably_damaging	0,99	neutral	0,17	neutral	0,63	deleterious	-5,29	deleterious	-4,34	medium_impact	3,13	neutral	0,63	neutral	0,41	deleterious	3,64	23,2	0,33	0,5	disease	0,93	disease	0,67	disease	0,58	disease	0,79	6	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,81	low_impact	-2,64	medium_impact	-0,15	medium_impact	1,66	0,61	0,8	14,1	15,36	N	0,32	N	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13969	13969	A	C	MI.22731	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1633	545	S	R	Agc/Cgc	-5,33	0	0	probably_damaging	0,94	neutral	0,35	neutral	0,64	deleterious	-3,91	deleterious	-4,31	medium_impact	3,13	neutral	0,63	neutral	0,41	deleterious	4,03	23,6	0,2	0,45	neutral	0,45	disease	0,84	disease	0,78	disease	0,8	6	neutral	0,95	neutral	0,21	deleterious	1	deleterious	0,8	low_impact	-1,88	medium_impact	0,08	medium_impact	1,66	0,62	0,8	14,1	15,36	N	0,4	N	0,96	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13969	13969	A	G	MI.22732	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1633	545	S	G	Agc/Ggc	-5,33	0	0	benign	0,12	neutral	0,34	neutral	1,24	neutral	0,83	deleterious	-3,16	neutral_impact	-0,14	neutral	0,78	neutral	0,92	neutral	1,07	11,06	0,38	0,5	neutral	0,38	neutral	0,05	neutral	0,27	neutral	0,19	6	neutral	0,61	deleterious	0,61	neutral	-6	deleterious	0,67	medium_impact	0,08	medium_impact	0,07	low_impact	-1,33	0,61	0,8	14,1	15,36	N	0,42	N	0,3	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13970	13970	G	C	MI.22733	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1634	545	S	T	aGc/aCc	0,86	0,54	0	possibly_damaging	0,86	neutral	0,41	neutral	0,67	deleterious	-3,02	deleterious	-2,61	medium_impact	3,13	neutral	0,68	neutral	0,55	deleterious	3,59	23,2	0,29	0,45	disease	0,51	neutral	0,39	disease	0,67	disease	0,53	1	neutral	0,86	neutral	0,28	NA	0	deleterious	0,73	low_impact	-1,5	medium_impact	0,15	medium_impact	1,66	0,61	0,8	14,1	15,36	N	0,34	N	0,65	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13970	13970	G	A	MI.22734	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1634	545	S	N	aGc/aAc	0,86	0,54	0	benign	0,17	neutral	0,34	neutral	0,65	deleterious	-3,77	deleterious	-2,54	medium_impact	2,58	neutral	0,81	neutral	0,52	deleterious	3,7	23,3	0,65	0,7	disease	0,65	disease	0,64	disease	0,62	disease	0,67	3	neutral	0,6	deleterious	0,59	neutral	-3	deleterious	0,79	medium_impact	-0,09	medium_impact	0,07	medium_impact	1,15	0,52	0,8	14,1	15,36	N	0,28	N	0,59	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13970	13970	G	T	MI.22735	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1634	545	S	I	aGc/aTc	0,86	0,54	0	probably_damaging	0,98	neutral	0,4	neutral	0,64	deleterious	-4,28	deleterious	-5,17	medium_impact	3,13	neutral	0,68	neutral	0,52	deleterious	4,34	24	0,33	0,5	disease	0,82	disease	0,72	disease	0,69	disease	0,76	5	neutral	0,98	neutral	0,21	deleterious	1	deleterious	0,82	low_impact	-2,35	medium_impact	0,14	medium_impact	1,66	0,62	0,8	14,1	15,36	N	0,3	N	0,97	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13972	13972	C	A	MI.22736	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1636	546	Q	K	Caa/Aaa	-1,44	0	0	probably_damaging	1	neutral	0,35	neutral	0,79	neutral	-1,6	deleterious	-2,96	medium_impact	2,88	neutral	0,67	neutral	0,52	deleterious	4,07	23,7	0,41	0,5	neutral	0,45	disease	0,72	disease	0,63	disease	0,63	3	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,08	medium_impact	1,43	0,44	0,8	12,77	12,9	N	0,33	N	0,71	polymorphism	0,68	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13972	13972	C	G	MI.22737	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1636	546	Q	E	Caa/Gaa	-1,44	0	0	probably_damaging	1	neutral	0,28	neutral	0,79	neutral	-1,62	neutral	-2,27	medium_impact	2,64	neutral	0,67	neutral	0,46	deleterious	3,25	22,8	0,41	0,5	neutral	0,44	disease	0,6	disease	0,63	disease	0,59	2	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,01	medium_impact	1,21	0,41	0,8	12,77	12,9	N	0,35	N	0,74	polymorphism	0,81	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13973	13973	A	C	MI.22738	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1637	546	Q	P	cAa/cCa	2,23	0,77	0,01	probably_damaging	1	neutral	0,21	neutral	0,7	deleterious	-3,9	deleterious	-4,58	high_impact	3,68	neutral	0,6	neutral	0,3	deleterious	3,49	23,1	0,19	0,45	disease	0,81	disease	0,81	disease	0,78	disease	0,82	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,09	high_impact	2,16	0,4	0,8	12,77	12,9	N	0,44	N	0,97	disease_causing	0,96	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13973	13973	A	G	MI.22739	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1637	546	Q	R	cAa/cGa	2,23	0,77	0,01	probably_damaging	1	neutral	0,35	neutral	0,74	neutral	-2,49	deleterious	-2,92	medium_impact	3,13	neutral	0,65	neutral	0,61	deleterious	3,61	23,2	0,48	0,55	neutral	0,46	disease	0,74	disease	0,69	disease	0,65	3	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,08	medium_impact	1,66	0,34	0,8	12,77	12,9	N	0,33	N	0,62	disease_causing	0,56	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6091	6091	T	A	MI.2274	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	188	63	F	Y	tTt/tAt	5,91	1	0	probably_damaging	0,99	deleterious	0	neutral	2,79	neutral	-1,22	neutral	-1,71	high_impact	4,75	neutral	0,64	neutral	0,51	deleterious	4,15	23,8	0,36	0,55	neutral	0,47	disease	0,84	disease	0,57	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	3,29	0,65	0,9	1,95	6,88	P	0,69	P	0,59	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13973	13973	A	T	MI.22740	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1637	546	Q	L	cAa/cTa	2,23	0,77	0,01	probably_damaging	1	neutral	0,69	neutral	0,76	neutral	-1,98	deleterious	-4,66	medium_impact	2,64	neutral	0,81	neutral	0,8	deleterious	3,98	23,6	0,27	0,45	disease	0,57	disease	0,78	disease	0,58	disease	0,56	1	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,42	medium_impact	1,21	0,21	0,8	12,77	12,9	N	0,24	N	0,65	disease_causing	0,95	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13974	13974	A	C	MI.22741	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1638	546	Q	H	caA/caC	3,61	0,8	0	probably_damaging	1	neutral	0,54	neutral	0,71	deleterious	-3,14	deleterious	-3,29	medium_impact	2,33	neutral	0,73	neutral	0,46	deleterious	3,48	23,1	0,51	0,6	disease	0,71	disease	0,68	disease	0,61	disease	0,61	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,27	medium_impact	0,93	0,56	0,8	12,77	12,9	N	0,28	N	0,67	disease_causing	0,91	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13974	13974	A	T	MI.22742	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1638	546	Q	H	caA/caT	3,61	0,8	0	probably_damaging	1	neutral	0,54	neutral	0,71	deleterious	-3,14	deleterious	-3,29	medium_impact	2,33	neutral	0,73	neutral	0,46	deleterious	3,69	23,3	0,51	0,6	disease	0,71	disease	0,68	disease	0,61	disease	0,61	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,27	medium_impact	0,93	0,56	0,8	12,77	12,9	N	0,29	N	0,67	disease_causing	0,91	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13975	13975	A	C	MI.22743	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1639	547	N	H	Aac/Cac	0,63	0,28	0	probably_damaging	1	neutral	0,53	neutral	0,9	neutral	-1,81	deleterious	-3,24	low_impact	1,11	neutral	0,84	neutral	0,81	neutral	1,58	13,73	0,59	0,65	disease	0,58	neutral	0,23	neutral	0,33	disease	0,55	1	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,26	medium_impact	-0,19	0,36	0,8	29,68	24,23	N	0,27	N	0,43	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13975	13975	A	G	MI.22744	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1639	547	N	D	Aac/Gac	0,63	0,28	0	probably_damaging	1	neutral	0,2	neutral	0,9	neutral	-1,88	deleterious	-3,2	medium_impact	2,36	neutral	0,8	neutral	0,41	deleterious	2,73	21	0,68	0,7	neutral	0,38	neutral	0,24	neutral	0,46	neutral	0,46	1	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,66	low_impact	-3,6	medium_impact	-0,1	medium_impact	0,95	0,36	0,8	29,68	24,23	N	0,34	N	0,67	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13975	13975	A	T	MI.22745	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1639	547	N	Y	Aac/Tac	0,63	0,28	0	probably_damaging	1	neutral	1	neutral	0,91	neutral	-1,51	deleterious	-5,17	low_impact	1,66	neutral	0,82	neutral	0,42	deleterious	2,31	18,24	0,32	0,5	disease	0,69	neutral	0,27	neutral	0,35	disease	0,57	1	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,71	low_impact	-3,6	high_impact	1,89	medium_impact	0,31	0,31	0,8	29,68	24,23	N	0,2	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13976	13976	A	G	MI.22746	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1640	547	N	S	aAc/aGc	1,54	0,23	0	probably_damaging	1	neutral	0,43	neutral	0,97	neutral	-0,34	deleterious	-2,94	low_impact	1,25	neutral	0,81	neutral	0,59	neutral	1,32	12,4	0,74	0,75	neutral	0,29	neutral	0,12	neutral	0,27	neutral	0,31	4	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,64	low_impact	-3,6	medium_impact	0,17	medium_impact	-0,06	0,17	0,8	29,68	24,23	N	0,31	N	0,33	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13976	13976	A	T	MI.22747	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1640	547	N	I	aAc/aTc	1,54	0,23	0	probably_damaging	1	neutral	0,47	neutral	0,95	neutral	-0,75	deleterious	-6,08	low_impact	1,8	neutral	0,82	neutral	0,41	deleterious	2,77	21,2	0,28	0,45	disease	0,65	neutral	0,29	neutral	0,43	disease	0,59	2	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,2	medium_impact	0,44	0,3	0,8	29,68	24,23	N	0,26	N	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13976	13976	A	C	MI.22748	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1640	547	N	T	aAc/aCc	1,54	0,23	0	probably_damaging	1	neutral	0,44	neutral	0,98	neutral	-0,23	deleterious	-3,58	low_impact	1,03	neutral	0,81	neutral	0,69	neutral	1,39	12,72	0,51	0,6	neutral	0,33	neutral	0,07	neutral	0,22	neutral	0,24	5	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,63	low_impact	-3,6	medium_impact	0,18	medium_impact	-0,26	0,35	0,8	29,68	24,23	N	0,34	N	0,42	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13977	13977	C	G	MI.22749	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1641	547	N	K	aaC/aaG	0,4	0,02	0	probably_damaging	1	neutral	0,32	neutral	1,07	neutral	0,65	deleterious	-2,59	neutral_impact	0,78	neutral	0,8	neutral	0,91	neutral	1,49	13,25	0,62	0,65	neutral	0,18	neutral	0,09	neutral	0,23	neutral	0,24	5	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,63	low_impact	-3,6	medium_impact	0,05	medium_impact	-0,49	0,43	0,8	29,68	24,23	N	0,4	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6091	6091	T	C	MI.2275	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	188	63	F	S	tTt/tCt	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,83	neutral	-0,4	deleterious	-4,48	high_impact	4,06	neutral	0,72	neutral	0,64	deleterious	4,12	23,8	0,32	0,55	neutral	0,29	disease	0,88	disease	0,57	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,65	0,48	0,9	1,95	6,88	P	0,53	P	0,84	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13977	13977	C	A	MI.22750	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1641	547	N	K	aaC/aaA	0,4	0,02	0	probably_damaging	1	neutral	0,32	neutral	1,07	neutral	0,65	deleterious	-2,59	neutral_impact	0,78	neutral	0,8	neutral	0,91	deleterious	1,96	15,94	0,62	0,65	neutral	0,18	neutral	0,09	neutral	0,23	neutral	0,24	5	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,63	low_impact	-3,6	medium_impact	0,05	medium_impact	-0,49	0,43	0,8	29,68	24,23	N	0,4	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13978	13978	C	A	MI.22751	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1642	548	L	M	Ctg/Atg	-5,79	0	0	benign	0,41	neutral	0,23	neutral	0,77	neutral	-1,87	neutral	-0,43	neutral_impact	-0,02	neutral	0,88	neutral	0,99	deleterious	2,36	18,57	0,31	0,45	disease	0,52	neutral	0,15	neutral	0,19	neutral	0,27	5	neutral	0,73	neutral	0,41	neutral	-6	deleterious	0,66	medium_impact	-0,6	medium_impact	-0,06	low_impact	-1,22	0,65	0,8	32,34	19,98	N	0,51	P	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13978	13978	C	G	MI.22752	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1642	548	L	V	Ctg/Gtg	-5,79	0	0	benign	0,05	neutral	0,5	neutral	0,84	neutral	-1,08	neutral	-1,1	low_impact	0,8	neutral	0,89	neutral	0,92	deleterious	2,23	17,72	0,41	0,5	neutral	0,3	neutral	0,15	neutral	0,21	neutral	0,31	4	neutral	0,45	deleterious	0,73	neutral	-6	deleterious	0,64	medium_impact	0,47	medium_impact	0,23	medium_impact	-0,47	0,32	0,8	32,34	19,98	N	0,44	N	0,27	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13979	13979	T	G	MI.22753	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1643	548	L	R	cTg/cGg	-2,35	0	0	probably_damaging	0,93	neutral	0,35	neutral	0,7	deleterious	-3,78	deleterious	-3,34	low_impact	1,84	neutral	0,68	neutral	0,53	deleterious	4,39	24,1	0,25	0,45	disease	0,52	disease	0,74	disease	0,69	disease	0,75	5	neutral	0,94	neutral	0,21	neutral	-2	deleterious	0,78	low_impact	-1,81	medium_impact	0,08	medium_impact	0,48	0,42	0,8	32,34	19,98	N	0,28	N	0,71	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13979	13979	T	C	MI.22754	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1643	548	L	P	cTg/cCg	-2,35	0	0	probably_damaging	0,97	neutral	0,2	neutral	0,69	deleterious	-4,42	deleterious	-3,88	low_impact	1,5	neutral	0,61	neutral	0,46	deleterious	4,07	23,7	0,17	0,45	disease	0,72	disease	0,77	disease	0,69	disease	0,78	6	neutral	0,98	neutral	0,12	neutral	-2	deleterious	0,83	low_impact	-2,18	medium_impact	-0,1	medium_impact	0,17	0,49	0,8	32,34	19,98	N	0,28	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13979	13979	T	A	MI.22755	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1643	548	L	Q	cTg/cAg	-2,35	0	0	probably_damaging	0,95	neutral	0,31	neutral	0,69	deleterious	-3,92	deleterious	-3,1	low_impact	1,5	neutral	0,75	neutral	0,64	deleterious	4,37	24,1	0,25	0,45	disease	0,51	neutral	0,48	disease	0,56	disease	0,58	2	neutral	0,96	neutral	0,18	neutral	-2	deleterious	0,71	low_impact	-1,96	medium_impact	0,04	medium_impact	0,17	0,45	0,8	32,34	19,98	N	0,33	N	0,65	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13981	13981	C	A	MI.22756	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1645	549	P	T	Ccc/Acc	-3,73	0	0	benign	0,01	neutral	0,62	neutral	1,06	neutral	2,11	neutral	0,84	neutral_impact	-1,5	neutral	0,79	neutral	0,81	deleterious	2,1	16,85	0,32	0,5	neutral	0,42	neutral	0,07	neutral	0,24	neutral	0,28	4	neutral	0,36	deleterious	0,81	neutral	-6	neutral	0,3	medium_impact	1,15	medium_impact	0,35	low_impact	-2,57	0,46	0,8	15,75	11,72	N	0,32	N	0,24	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13981	13981	C	G	MI.22757	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1645	549	P	A	Ccc/Gcc	-3,73	0	0	benign	0	neutral	0,57	neutral	1,27	neutral	4,1	neutral	3,19	neutral_impact	-3,48	neutral	0,8	neutral	0,96	neutral	-1,41	0	0,33	0,5	neutral	0,25	neutral	0,04	neutral	0,11	neutral	0,24	5	neutral	0,43	deleterious	0,79	neutral	-6	neutral	0,1	high_impact	2,1	medium_impact	0,3	low_impact	-4,38	0,58	0,8	15,75	11,72	N	0,39	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13981	13981	C	T	MI.22758	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1645	549	P	S	Ccc/Tcc	-3,73	0	0	benign	0,01	neutral	0,42	neutral	1,1	neutral	2,74	neutral	1,8	neutral_impact	-2,27	neutral	0,84	neutral	0,95	neutral	0,92	10,21	0,39	0,5	neutral	0,28	neutral	0,07	neutral	0,14	neutral	0,29	4	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,11	medium_impact	1,15	medium_impact	0,16	low_impact	-3,28	0,24	0,8	15,75	11,72	N	0,38	N	0,02	polymorphism	1	0	rs201144988	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13982	13982	C	A	MI.22759	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1646	549	P	H	cCc/cAc	0,17	0,09	0	possibly_damaging	0,84	neutral	0,54	neutral	1,02	neutral	0,96	neutral	-1,05	neutral_impact	0	neutral	0,74	neutral	0,54	deleterious	4,09	23,7	0,32	0,5	disease	0,67	neutral	0,21	disease	0,54	neutral	0,48	0	neutral	0,82	neutral	0,35	neutral	-3	deleterious	0,67	low_impact	-1,43	medium_impact	0,27	low_impact	-1,2	0,36	0,8	15,75	11,72	N	0,3	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6091	6091	T	G	MI.2276	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	188	63	F	C	tTt/tGt	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-2,08	deleterious	-4,38	high_impact	4,75	neutral	0,62	neutral	0,52	deleterious	3,96	23,6	0,22	0,55	disease	0,59	disease	0,9	disease	0,6	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,3	0,9	1,95	6,88	P	0,67	P	0,91	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13982	13982	C	T	MI.22760	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1646	549	P	L	cCc/cTc	0,17	0,09	0	benign	0,05	neutral	0,94	neutral	1,17	neutral	3,44	neutral	-0,53	neutral_impact	-0,55	neutral	0,76	neutral	0,54	deleterious	2,87	21,7	0,29	0,45	neutral	0,27	neutral	0,24	neutral	0,4	neutral	0,41	2	neutral	0,01	deleterious	0,95	neutral	-6	neutral	0,3	medium_impact	0,47	medium_impact	0,89	low_impact	-1,71	0,75	0,85	15,75	11,72	N	0,32	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13982	13982	C	G	MI.22761	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1646	549	P	R	cCc/cGc	0,17	0,09	0	benign	0,23	neutral	0,31	neutral	1,01	neutral	0,77	neutral	-0,4	neutral_impact	0	neutral	0,71	neutral	0,5	deleterious	2,17	17,28	0,27	0,45	neutral	0,47	neutral	0,41	disease	0,58	neutral	0,47	1	neutral	0,63	deleterious	0,54	neutral	-6	deleterious	0,51	medium_impact	-0,25	medium_impact	0,04	low_impact	-1,2	0,5	0,8	15,75	11,72	N	0,41	N	0,37	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13984	13984	C	G	MI.22762	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1648	550	L	V	Cta/Gta	-2,12	0	0	possibly_damaging	0,44	neutral	0,55	neutral	0,97	neutral	-0,82	neutral	-0,1	low_impact	1,2	neutral	0,75	neutral	0,73	deleterious	3,22	22,7	0,42	0,55	neutral	0,36	neutral	0,16	neutral	0,41	neutral	0,33	3	neutral	0,42	deleterious	0,56	neutral	-3	deleterious	0,51	medium_impact	-0,65	medium_impact	0,28	medium_impact	-0,11	0,48	0,8	25,7	16,16	N	0,32	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13984	13984	C	A	MI.22763	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1648	550	L	M	Cta/Ata	-2,12	0	0	probably_damaging	0,93	neutral	0,24	neutral	0,95	neutral	-1,8	neutral	0,4	neutral_impact	0,4	neutral	0,82	neutral	0,85	deleterious	3,88	23,5	0,24	0,45	disease	0,57	neutral	0,17	neutral	0,27	neutral	0,36	3	neutral	0,95	neutral	0,16	neutral	-2	deleterious	0,67	low_impact	-1,81	medium_impact	-0,04	medium_impact	-0,84	0,49	0,8	25,7	16,16	N	0,44	N	0,53	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13985	13985	T	A	MI.22764	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1649	550	L	Q	cTa/cAa	-0,75	0	0	probably_damaging	0,9	neutral	0,37	neutral	1,02	neutral	0,38	neutral	0,51	low_impact	1,2	neutral	0,72	neutral	0,7	deleterious	4,16	23,8	0,21	0,45	disease	0,69	neutral	0,39	neutral	0,46	disease	0,65	3	neutral	0,91	neutral	0,24	neutral	-2	deleterious	0,7	low_impact	-1,65	medium_impact	0,11	medium_impact	-0,11	0,4	0,8	25,7	16,16	N	0,39	N	0,69	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13985	13985	T	C	MI.22765	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1649	550	L	P	cTa/cCa	-0,75	0	0	probably_damaging	0,9	neutral	0,23	neutral	0,96	neutral	-1,39	neutral	-0,18	low_impact	1,2	damaging	0,58	neutral	0,47	deleterious	3,96	23,6	0,15	0,4	disease	0,69	disease	0,72	disease	0,62	disease	0,74	5	neutral	0,93	neutral	0,17	neutral	-2	deleterious	0,77	low_impact	-1,65	medium_impact	-0,06	medium_impact	-0,11	0,56	0,8	25,7	16,16	N	0,37	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13985	13985	T	G	MI.22766	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1649	550	L	R	cTa/cGa	-0,75	0	0	possibly_damaging	0,87	neutral	0,4	neutral	1,01	neutral	0,21	neutral	-0,06	low_impact	1,2	neutral	0,68	neutral	0,55	deleterious	4,22	23,9	0,22	0,45	disease	0,61	disease	0,66	disease	0,54	disease	0,71	4	neutral	0,87	neutral	0,27	neutral	-3	deleterious	0,72	low_impact	-1,53	medium_impact	0,14	medium_impact	-0,11	0,61	0,8	25,7	16,16	N	0,33	N	0,67	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13987	13987	C	T	MI.22767	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1651	551	L	F	Ctc/Ttc	-12,44	0	0	benign	0,06	neutral	0,72	neutral	0,94	neutral	-2,47	neutral	-1,17	low_impact	1,25	neutral	0,82	neutral	0,84	deleterious	2,13	17,05	0,4	0,5	disease	0,78	neutral	0,24	neutral	0,31	disease	0,59	2	neutral	0,19	deleterious	0,83	neutral	-6	deleterious	0,73	medium_impact	0,39	medium_impact	0,46	medium_impact	-0,06	0,31	0,8	30,35	21,25	N	0,29	N	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13987	13987	C	G	MI.22768	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1651	551	L	V	Ctc/Gtc	-12,44	0	0	benign	0,33	neutral	0,51	neutral	0,97	neutral	-0,57	neutral	0	low_impact	1,8	neutral	0,81	neutral	0,78	deleterious	1,84	15,21	0,34	0,5	neutral	0,41	neutral	0,15	neutral	0,31	neutral	0,32	4	neutral	0,4	deleterious	0,59	neutral	-6	deleterious	0,66	medium_impact	-0,45	medium_impact	0,24	medium_impact	0,44	0,38	0,8	30,35	21,25	N	0,38	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13987	13987	C	A	MI.22769	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1651	551	L	I	Ctc/Atc	-12,44	0	0	benign	0,06	neutral	0,44	neutral	0,96	neutral	-0,91	neutral	-0,2	low_impact	0,9	neutral	0,8	neutral	0,76	deleterious	2,67	20,6	0,38	0,5	disease	0,58	neutral	0,16	neutral	0,29	neutral	0,36	3	neutral	0,51	deleterious	0,69	neutral	-6	deleterious	0,69	medium_impact	0,39	medium_impact	0,18	medium_impact	-0,38	0,4	0,8	30,35	21,25	N	0,37	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6092	6092	T	G	MI.2277	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	189	63	F	L	ttT/ttG	5,91	1	0	probably_damaging	0,99	neutral	0,19	neutral	2,95	neutral	1,58	deleterious	-2,79	low_impact	1,23	damaging	0,56	neutral	0,64	deleterious	3,08	22,5	0,44	0,55	neutral	0,18	disease	0,61	neutral	0,34	neutral	0,4	2	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,68	low_impact	-2,64	medium_impact	-0,16	medium_impact	0,04	0,6	0,9	1,95	6,88	P	0,59	P	0,83	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13988	13988	T	C	MI.22770	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1652	551	L	P	cTc/cCc	-0,29	0	0	probably_damaging	0,93	neutral	0,21	neutral	0,95	neutral	-1,7	neutral	-1,25	low_impact	1,45	neutral	0,61	neutral	0,47	deleterious	2,84	21,6	0,15	0,4	disease	0,58	disease	0,72	disease	0,65	disease	0,74	5	neutral	0,95	neutral	0,14	neutral	-2	deleterious	0,78	low_impact	-1,81	medium_impact	-0,09	medium_impact	0,12	0,49	0,8	30,35	21,25	N	0,3	N	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13988	13988	T	G	MI.22771	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1652	551	L	R	cTc/cGc	-0,29	0	0	probably_damaging	0,91	neutral	0,36	neutral	1,03	neutral	0,5	neutral	-0,8	low_impact	1,25	neutral	0,75	neutral	0,74	deleterious	2,84	21,6	0,2	0,45	neutral	0,37	disease	0,63	neutral	0,44	neutral	0,49	0	neutral	0,91	neutral	0,23	neutral	-2	deleterious	0,72	low_impact	-1,7	medium_impact	0,1	medium_impact	-0,06	0,46	0,8	30,35	21,25	N	0,36	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13988	13988	T	A	MI.22772	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1652	551	L	H	cTc/cAc	-0,29	0	0	probably_damaging	0,97	neutral	0,54	neutral	1,02	neutral	0,27	neutral	-1,24	neutral_impact	-0,26	neutral	0,71	neutral	0,89	deleterious	2,58	19,99	0,22	0,45	neutral	0,32	neutral	0,13	neutral	0,16	neutral	0,28	4	neutral	0,96	neutral	0,29	neutral	-2	deleterious	0,65	low_impact	-2,18	medium_impact	0,27	low_impact	-1,44	0,35	0,8	30,35	21,25	N	0,38	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13990	13990	C	T	MI.22773	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1654	552	L	F	Ctc/Ttc	-3,04	0	0	probably_damaging	1	neutral	0,7	neutral	3,64	neutral	-1,99	deleterious	-2,51	medium_impact	2,71	neutral	0,72	damaging	0,16	deleterious	4,16	23,8	0,3	0,45	disease	0,55	neutral	0,34	disease	0,54	disease	0,62	2	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,71	low_impact	-3,6	medium_impact	0,44	medium_impact	1,27	0,48	0,8	9,29	9,55	N	0,21	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13990	13990	C	A	MI.22774	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1654	552	L	I	Ctc/Atc	-3,04	0	0	probably_damaging	1	neutral	0,4	neutral	3,72	neutral	-0,92	neutral	-0,78	medium_impact	1,98	neutral	0,81	neutral	0,95	deleterious	3,2	22,7	0,31	0,45	disease	0,51	neutral	0,16	neutral	0,2	neutral	0,27	5	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,69	low_impact	-3,6	medium_impact	0,14	medium_impact	0,61	0,41	0,8	9,29	9,55	N	0,43	N	0,85	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13990	13990	C	G	MI.22775	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1654	552	L	V	Ctc/Gtc	-3,04	0	0	probably_damaging	1	neutral	0,51	neutral	3,73	neutral	-0,38	neutral	-1,24	medium_impact	2,55	neutral	0,84	neutral	0,31	deleterious	3,57	23,1	0,33	0,5	neutral	0,5	neutral	0,19	neutral	0,26	neutral	0,31	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,69	low_impact	-3,6	medium_impact	0,24	medium_impact	1,13	0,4	0,8	9,29	9,55	N	0,3	N	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13991	13991	T	C	MI.22776	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1655	552	L	P	cTc/cCc	-1,89	0	0	probably_damaging	1	neutral	0,21	neutral	3,6	deleterious	-3,1	deleterious	-4,25	high_impact	3,52	damaging	0,6	damaging	0,1	deleterious	4,07	23,7	0,13	0,4	disease	0,85	disease	0,75	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,09	high_impact	2,01	0,42	0,8	9,29	9,55	N	0,25	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13991	13991	T	G	MI.22777	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1655	552	L	R	cTc/cGc	-1,89	0	0	probably_damaging	1	neutral	0,36	neutral	3,62	neutral	-2,16	deleterious	-3,73	high_impact	3,52	neutral	0,79	damaging	0,19	deleterious	4,32	24	0,18	0,45	disease	0,56	disease	0,72	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,1	high_impact	2,01	0,49	0,8	9,29	9,55	N	0,27	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13991	13991	T	A	MI.22778	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1655	552	L	H	cTc/cAc	-1,89	0	0	probably_damaging	1	neutral	0,54	neutral	3,61	neutral	-2,96	deleterious	-4,41	high_impact	3,52	neutral	0,73	damaging	0,16	deleterious	4,31	24	0,19	0,45	disease	0,78	disease	0,6	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,77	low_impact	-3,6	medium_impact	0,27	high_impact	2,01	0,38	0,8	9,29	9,55	N	0,23	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13993	13993	C	A	MI.22779	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1657	553	L	M	Cta/Ata	-3,73	0	0	probably_damaging	1	neutral	0,24	neutral	0,79	neutral	-1,97	neutral	-0,66	neutral_impact	0,78	neutral	0,81	neutral	0,93	deleterious	2,56	19,86	0,3	0,45	disease	0,74	neutral	0,12	neutral	0,19	neutral	0,4	2	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	-0,04	medium_impact	-0,49	0,73	0,85	18,57	16,72	N	0,47	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6092	6092	T	A	MI.2278	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	189	63	F	L	ttT/ttA	5,91	1	0	probably_damaging	0,99	neutral	0,19	neutral	2,95	neutral	1,58	deleterious	-2,79	low_impact	1,23	damaging	0,56	neutral	0,64	deleterious	3,21	22,7	0,44	0,55	neutral	0,18	disease	0,61	neutral	0,34	neutral	0,4	2	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,68	low_impact	-2,64	medium_impact	-0,16	medium_impact	0,04	0,6	0,9	1,95	6,88	P	0,59	P	0,83	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13993	13993	C	G	MI.22780	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1657	553	L	V	Cta/Gta	-3,73	0	0	probably_damaging	1	neutral	0,51	neutral	0,85	neutral	-1,1	neutral	-1,83	low_impact	1,04	neutral	0,77	neutral	0,46	neutral	1,71	14,47	0,37	0,5	neutral	0,43	neutral	0,06	neutral	0,19	neutral	0,27	5	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,65	low_impact	-3,6	medium_impact	0,24	medium_impact	-0,25	0,51	0,8	18,57	16,72	N	0,36	N	0,62	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13994	13994	T	A	MI.22781	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1658	553	L	Q	cTa/cAa	-0,75	0	0	probably_damaging	1	neutral	0,35	neutral	0,74	deleterious	-3,76	deleterious	-4,37	medium_impact	2,67	neutral	0,73	damaging	0,13	deleterious	4,25	23,9	0,2	0,45	disease	0,67	neutral	0,47	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,08	medium_impact	1,24	0,4	0,8	18,57	16,72	N	0,3	N	0,97	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13994	13994	T	G	MI.22782	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1658	553	L	R	cTa/cGa	-0,75	0	0	probably_damaging	1	neutral	0,34	neutral	0,74	deleterious	-3,6	deleterious	-4,57	medium_impact	2,67	neutral	0,66	damaging	0,11	deleterious	4,34	24	0,18	0,45	disease	0,66	disease	0,67	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,07	medium_impact	1,24	0,53	0,8	18,57	16,72	N	0,24	N	0,96	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13994	13994	T	C	MI.22783	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1658	553	L	P	cTa/cCa	-0,75	0	0	probably_damaging	1	neutral	0,21	neutral	0,73	deleterious	-4,21	deleterious	-5,35	medium_impact	2,67	damaging	0,59	damaging	0,1	deleterious	4,08	23,7	0,15	0,45	disease	0,83	disease	0,74	disease	0,71	disease	0,79	6	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	-0,09	medium_impact	1,24	0,39	0,8	18,57	16,72	N	0,21	N	0,89	disease_causing	0,56	0,21	.	.	.	.	.	endometrial and ovarian tumors	.	.	.	.	.	.	.	.	.
chrM	13996	13996	G	C	MI.22784	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1660	554	D	H	Gac/Cac	-2,58	0	0	probably_damaging	1	neutral	0,54	neutral	-0,7	deleterious	-7,83	deleterious	-6,18	high_impact	3,82	damaging	0,54	damaging	0,1	deleterious	3,77	23,4	0,32	0,5	disease	0,83	disease	0,76	disease	0,83	disease	0,81	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,27	high_impact	2,29	0,56	0,8	26,37	7,08	N	0,35	N	0,99	disease_causing	0,92	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13996	13996	G	A	MI.22785	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1660	554	D	N	Gac/Aac	-2,58	0	0	probably_damaging	1	neutral	0,4	neutral	-0,66	deleterious	-5,96	deleterious	-4,41	medium_impact	3,48	damaging	0,46	damaging	0,11	deleterious	4,37	24,1	0,53	0,6	disease	0,62	disease	0,66	disease	0,81	disease	0,75	5	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,14	medium_impact	1,98	0,7	0,85	26,37	7,08	N	0,42	N	0,98	disease_causing	0,7	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13996	13996	G	T	MI.22786	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1660	554	D	Y	Gac/Tac	-2,58	0	0	probably_damaging	1	neutral	1	neutral	-0,71	deleterious	-9,11	deleterious	-7,94	high_impact	3,82	damaging	0,54	damaging	0,1	deleterious	4,07	23,7	0,2	0,45	disease	0,89	disease	0,8	disease	0,82	disease	0,85	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,83	low_impact	-3,6	high_impact	1,89	high_impact	2,29	0,35	0,8	26,37	7,08	N	0,36	N	0,99	disease_causing	0,96	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13997	13997	A	C	MI.22787	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1661	554	D	A	gAc/gCc	8,88	1	0	probably_damaging	1	neutral	0,62	neutral	-0,68	deleterious	-6,76	deleterious	-7,06	medium_impact	3,48	damaging	0,55	damaging	0,12	deleterious	3,79	23,4	0,26	0,45	disease	0,67	disease	0,66	disease	0,79	disease	0,76	5	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,35	medium_impact	1,98	0,48	0,8	26,37	7,08	P	0,53	P	0,94	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13997	13997	A	T	MI.22788	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1661	554	D	V	gAc/gTc	8,88	1	0	probably_damaging	1	neutral	0,56	neutral	-0,7	deleterious	-8,49	deleterious	-7,92	high_impact	3,82	damaging	0,48	damaging	0,12	deleterious	3,88	23,5	0,2	0,45	disease	0,76	disease	0,74	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,8	low_impact	-3,6	medium_impact	0,29	high_impact	2,29	0,36	0,8	26,37	7,08	P	0,55	P	0,99	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13997	13997	A	G	MI.22789	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1661	554	D	G	gAc/gGc	8,88	1	0	probably_damaging	1	neutral	0,39	neutral	-0,68	deleterious	-6,76	deleterious	-6,18	high_impact	3,82	damaging	0,5	damaging	0,13	deleterious	4,1	23,7	0,28	0,45	disease	0,8	disease	0,65	disease	0,79	disease	0,76	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,13	high_impact	2,29	0,43	0,8	26,37	7,08	P	0,58	P	0,98	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6093	6093	G	A	MI.2279	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	190	64	V	M	Gta/Ata	-8,66	0	0	possibly_damaging	0,84	neutral	0,18	neutral	2,74	neutral	-1,71	neutral	-1,27	medium_impact	2,52	neutral	0,66	neutral	0,57	deleterious	3,43	23	0,44	0,55	disease	0,61	disease	0,59	neutral	0,36	neutral	0,5	0	neutral	0,91	neutral	0,17	NA	0	deleterious	0,69	low_impact	-1,43	medium_impact	-0,17	medium_impact	1,23	0,96	1	12,87	22,39	N	0,36	N	0,82	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13998	13998	C	G	MI.22790	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1662	554	D	E	gaC/gaG	8,42	1	0	probably_damaging	1	neutral	0,43	neutral	-0,6	deleterious	-4,78	deleterious	-3,53	medium_impact	2,03	damaging	0,5	damaging	0,19	deleterious	4,07	23,7	0,48	0,55	neutral	0,48	disease	0,6	disease	0,71	disease	0,67	3	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,17	medium_impact	0,65	0,55	0,8	26,37	7,08	P	0,55	P	0,91	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13998	13998	C	A	MI.22791	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1662	554	D	E	gaC/gaA	8,42	1	0	probably_damaging	1	neutral	0,43	neutral	-0,6	deleterious	-4,78	deleterious	-3,53	medium_impact	2,03	damaging	0,5	damaging	0,19	deleterious	4,4	24,1	0,48	0,55	neutral	0,48	disease	0,6	disease	0,71	disease	0,67	3	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,17	medium_impact	0,65	0,55	0,8	26,37	7,08	P	0,56	P	0,91	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13999	13999	C	G	MI.22792	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1663	555	L	V	Cta/Gta	-2,58	0	0	possibly_damaging	0,79	neutral	0,51	neutral	0,88	neutral	-1,96	neutral	-1,67	medium_impact	2,47	neutral	0,75	neutral	0,64	deleterious	2,28	18,06	0,32	0,5	disease	0,6	neutral	0,26	neutral	0,36	disease	0,57	1	neutral	0,77	neutral	0,36	NA	0	deleterious	0,72	low_impact	-1,29	medium_impact	0,24	medium_impact	1,05	0,48	0,8	10,95	11,63	N	0,31	N	0,39	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	13999	13999	C	A	MI.22793	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1663	555	L	M	Cta/Ata	-2,58	0	0	probably_damaging	0,96	neutral	0,23	neutral	0,9	neutral	-1,53	neutral	-0,64	medium_impact	2,12	neutral	0,86	neutral	0,97	deleterious	2,83	21,5	0,29	0,45	disease	0,61	neutral	0,22	neutral	0,2	neutral	0,46	1	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,7	low_impact	-2,06	medium_impact	-0,06	medium_impact	0,73	0,7	0,85	10,95	11,63	N	0,52	P	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14000	14000	T	G	MI.22794	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1664	555	L	R	cTa/cGa	-5,56	0	0	probably_damaging	0,95	neutral	0,35	neutral	0,96	neutral	-0,47	deleterious	-3,38	medium_impact	2,47	neutral	0,78	neutral	0,75	deleterious	3,14	22,6	0,21	0,45	neutral	0,27	disease	0,69	neutral	0,47	disease	0,53	1	neutral	0,96	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-1,96	medium_impact	0,08	medium_impact	1,05	0,55	0,8	10,95	11,63	N	0,31	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14000	14000	T	A	MI.22795	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1664	555	L	Q	cTa/cAa	-5,56	0	0	probably_damaging	0,95	neutral	0,31	neutral	1,15	neutral	1,05	deleterious	-2,98	low_impact	1,06	neutral	0,83	neutral	0,87	deleterious	1,99	16,14	0,2	0,45	neutral	0,47	neutral	0,12	neutral	0,22	neutral	0,32	4	neutral	0,96	neutral	0,18	neutral	-2	deleterious	0,68	low_impact	-1,96	medium_impact	0,04	medium_impact	-0,23	0,48	0,8	10,95	11,63	N	0,36	N	0,75	polymorphism	1	0,06	rs28359185	Likely benign	not_provided	RCV000224850.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	14000	14000	T	C	MI.22796	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1664	555	L	P	cTa/cCa	-5,56	0	0	probably_damaging	0,96	neutral	0,21	neutral	0,87	neutral	-2,33	deleterious	-4,14	medium_impact	3,37	neutral	0,61	neutral	0,33	deleterious	2,97	22,1	0,15	0,4	disease	0,62	disease	0,8	disease	0,57	disease	0,75	5	neutral	0,98	neutral	0,13	deleterious	1	deleterious	0,81	low_impact	-2,06	medium_impact	-0,09	medium_impact	1,88	0,44	0,8	10,95	11,63	N	0,3	N	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14002	14002	A	T	MI.22797	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1666	556	T	S	Acc/Tcc	-1,67	0	0,02	benign	0,11	neutral	0,45	neutral	1	neutral	0,01	neutral	-1,64	neutral_impact	0,73	neutral	0,83	neutral	0,82	deleterious	0,46	7,08	0,41	0,5	neutral	0,39	neutral	0,15	neutral	0,24	neutral	0,31	4	neutral	0,48	deleterious	0,67	neutral	-6	neutral	0,31	medium_impact	0,12	medium_impact	0,18	medium_impact	-0,54	0,45	0,8	30,35	18,65	N	0,41	N	0,32	polymorphism	1	0,03	rs386829198	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14002	14002	A	G	MI.22798	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1666	556	T	A	Acc/Gcc	-1,67	0	0,02	benign	0	neutral	0,59	neutral	0,89	neutral	-1,01	neutral	-1,46	low_impact	1,31	neutral	0,87	neutral	0,93	deleterious	0,53	7,65	0,51	0,6	neutral	0,38	neutral	0,2	neutral	0,29	neutral	0,38	2	neutral	0,4	deleterious	0,8	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,32	medium_impact	-0,01	0,41	0,8	30,35	18,65	N	0,36	N	0,1	polymorphism	1	0,03	rs386829198	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14002	14002	A	C	MI.22799	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1666	556	T	P	Acc/Ccc	-1,67	0	0,02	benign	0,41	neutral	0,21	neutral	0,79	deleterious	-3,69	deleterious	-2,98	medium_impact	2,81	damaging	0,59	neutral	0,33	deleterious	3,22	22,7	0,15	0,4	disease	0,71	disease	0,71	disease	0,65	disease	0,72	4	neutral	0,76	neutral	0,4	neutral	-3	deleterious	0,63	medium_impact	-0,6	medium_impact	-0,09	medium_impact	1,36	0,47	0,8	30,35	18,65	N	0,29	N	0,77	polymorphism	1	0,24	rs386829198	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8633	8633	A	C	MI.228	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	107	36	Y	S	tAt/tCt	2,9	0,2	0	benign	0,08	neutral	0,37	neutral	4,51	neutral	2,68	neutral	-0,56	neutral_impact	-0,39	neutral	0,83	neutral	0,51	neutral	1,58	13,74	0,49	0,65	neutral	0,39	neutral	0,46	neutral	0,4	neutral	0,49	0	neutral	0,59	deleterious	0,65	neutral	-6	neutral	0,22	medium_impact	0,25	medium_impact	0,16	low_impact	-1,43	0,4	0,9	29,2	23,72	N	0,32	N	0,16	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6093	6093	G	C	MI.2280	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	190	64	V	L	Gta/Cta	-8,66	0	0	benign	0,04	neutral	0,32	neutral	2,94	neutral	0,01	neutral	-0,9	low_impact	0,88	neutral	0,66	neutral	0,53	deleterious	0,22	4,91	0,36	0,55	neutral	0,16	neutral	0,5	neutral	0,28	neutral	0,43	2	neutral	0,66	deleterious	0,64	neutral	-6	neutral	0,16	medium_impact	0,54	medium_impact	0,01	medium_impact	-0,29	0,62	0,9	12,87	22,39	N	0,43	N	0,55	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14003	14003	C	A	MI.22800	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1667	556	T	N	aCc/aAc	-0,52	0	0,01	benign	0,41	neutral	0,36	neutral	0,82	neutral	-2,34	deleterious	-2,54	low_impact	1,07	neutral	0,84	neutral	0,84	deleterious	2,29	18,11	0,39	0,5	neutral	0,49	neutral	0,46	neutral	0,29	neutral	0,45	1	neutral	0,58	deleterious	0,48	neutral	-6	deleterious	0,54	medium_impact	-0,6	medium_impact	0,1	medium_impact	-0,23	0,61	0,8	30,35	18,65	N	0,36	N	0,41	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14003	14003	C	G	MI.22801	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1667	556	T	S	aCc/aGc	-0,52	0	0,01	benign	0,11	neutral	0,45	neutral	1	neutral	0,01	neutral	-1,64	neutral_impact	0,73	neutral	0,83	neutral	0,82	deleterious	0,65	8,46	0,41	0,5	neutral	0,39	neutral	0,15	neutral	0,24	neutral	0,31	4	neutral	0,48	deleterious	0,67	neutral	-6	neutral	0,31	medium_impact	0,12	medium_impact	0,18	medium_impact	-0,54	0,45	0,8	30,35	18,65	N	0,38	N	0,32	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14003	14003	C	T	MI.22802	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1667	556	T	I	aCc/aTc	-0,52	0	0,01	benign	0	neutral	0,42	neutral	0,79	deleterious	-3,65	neutral	0,38	low_impact	1,31	neutral	0,85	neutral	0,96	deleterious	0,37	6,36	0,32	0,5	neutral	0,35	neutral	0,26	neutral	0,29	neutral	0,46	1	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,14	high_impact	2,1	medium_impact	0,16	medium_impact	-0,01	0,38	0,8	30,35	18,65	N	0,4	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14005	14005	T	G	MI.22803	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1669	557	W	G	Tga/Gga	-10,83	0	0	probably_damaging	1	neutral	0,39	neutral	-1,32	deleterious	-9,44	deleterious	-11,48	high_impact	3,72	neutral	0,64	damaging	0,13	deleterious	4,11	23,7	0,29	0,45	disease	0,53	disease	0,67	disease	0,81	disease	0,75	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,74	low_impact	-3,6	medium_impact	0,13	high_impact	2,2	0,21	0,8	15,75	7,29	N	0,34	N	0,97	polymorphism	0,97	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14005	14005	T	C	MI.22804	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1669	557	W	R	Tga/Cga	-10,83	0	0	probably_damaging	1	neutral	0,43	neutral	-1,32	deleterious	-9,4	deleterious	-12,36	high_impact	3,72	neutral	0,63	damaging	0,13	deleterious	3,72	23,3	0,29	0,45	disease	0,64	disease	0,8	disease	0,85	disease	0,83	7	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,17	high_impact	2,2	0,27	0,8	15,75	7,29	N	0,37	N	0,97	polymorphism	0,99	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14006	14006	G	C	MI.22805	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1670	557	W	S	tGa/tCa	7,27	1	0	probably_damaging	1	neutral	0,53	neutral	-1,32	deleterious	-9,23	deleterious	-12,36	medium_impact	2,83	neutral	0,64	damaging	0,15	deleterious	4,2	23,9	0,29	0,45	neutral	0,45	disease	0,74	disease	0,8	disease	0,78	6	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,26	medium_impact	1,38	0,19	0,8	15,75	7,29	N	0,39	N	0,95	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14006	14006	G	T	MI.22806	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1670	557	W	L	tGa/tTa	7,27	1	0	probably_damaging	1	neutral	0,7	neutral	-1,27	deleterious	-6,71	deleterious	-11,48	medium_impact	2,48	neutral	0,63	damaging	0,19	deleterious	4,39	24,1	0,23	0,45	neutral	0,41	disease	0,68	disease	0,77	disease	0,62	2	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,44	medium_impact	1,06	0,22	0,8	15,75	7,29	N	0,4	N	0,97	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14007	14007	A	C	MI.22807	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1671	557	W	C	tgA/tgC	7,27	1	0	probably_damaging	1	neutral	0,18	neutral	-1,32	deleterious	-10,73	deleterious	-11,48	high_impact	3,72	damaging	0,6	damaging	0,1	deleterious	4,17	23,8	0,27	0,45	disease	0,83	disease	0,71	disease	0,84	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	-0,13	high_impact	2,2	0,23	0,8	15,75	7,29	N	0,48	N	0,98	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14007	14007	A	T	MI.22808	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1671	557	W	C	tgA/tgT	7,27	1	0	probably_damaging	1	neutral	0,18	neutral	-1,32	deleterious	-10,73	deleterious	-11,48	high_impact	3,72	damaging	0,6	damaging	0,1	deleterious	4,29	24	0,27	0,45	disease	0,83	disease	0,71	disease	0,84	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	-0,13	high_impact	2,2	0,23	0,8	15,75	7,29	N	0,48	N	0,98	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14008	14008	C	G	MI.22809	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1672	558	L	V	Cta/Gta	1,54	0,8	0	probably_damaging	0,92	neutral	0,52	neutral	0,86	neutral	-1,07	neutral	-2,31	medium_impact	2,46	neutral	0,76	damaging	0,26	deleterious	3,62	23,2	0,33	0,5	neutral	0,32	neutral	0,26	disease	0,54	neutral	0,48	0	neutral	0,92	neutral	0,3	deleterious	1	deleterious	0,68	low_impact	-1,75	medium_impact	0,25	medium_impact	1,04	0,56	0,8	18,91	16,9	N	0,28	N	0,55	polymorphism	0,93	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6093	6093	G	T	MI.2281	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	190	64	V	L	Gta/Tta	-8,66	0	0	benign	0,04	neutral	0,32	neutral	2,94	neutral	0,01	neutral	-0,9	low_impact	0,88	neutral	0,66	neutral	0,53	deleterious	0,38	6,48	0,36	0,55	neutral	0,16	neutral	0,5	neutral	0,28	neutral	0,43	2	neutral	0,66	deleterious	0,64	neutral	-6	neutral	0,16	medium_impact	0,54	medium_impact	0,01	medium_impact	-0,29	0,62	0,9	12,87	22,39	N	0,43	N	0,55	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14008	14008	C	A	MI.22810	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1672	558	L	M	Cta/Ata	1,54	0,8	0	probably_damaging	0,99	neutral	0,25	neutral	0,81	neutral	-1,76	neutral	-1,5	low_impact	1,26	neutral	0,8	neutral	0,93	deleterious	2,79	21,3	0,25	0,45	disease	0,6	neutral	0,21	neutral	0,23	neutral	0,46	1	deleterious	0,99	neutral	0,13	neutral	-2	deleterious	0,71	low_impact	-2,64	medium_impact	-0,03	medium_impact	-0,05	0,64	0,8	18,91	16,9	N	0,34	N	0,63	polymorphism	0,94	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14009	14009	T	A	MI.22811	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1673	558	L	Q	cTa/cAa	-1,21	0	0	probably_damaging	1	neutral	0,37	neutral	0,79	neutral	-2,29	deleterious	-4,76	medium_impact	2,65	neutral	0,74	damaging	0,17	deleterious	4,54	24,3	0,16	0,45	disease	0,7	disease	0,55	disease	0,57	disease	0,64	3	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,11	medium_impact	1,22	0,5	0,8	18,91	16,9	N	0,28	N	0,96	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14009	14009	T	G	MI.22812	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1673	558	L	R	cTa/cGa	-1,21	0	0	probably_damaging	0,99	neutral	0,37	neutral	0,76	deleterious	-3,18	deleterious	-4,78	medium_impact	3	neutral	0,64	damaging	0,12	deleterious	4,39	24,1	0,12	0,4	disease	0,8	disease	0,73	disease	0,69	disease	0,76	5	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,85	low_impact	-2,64	medium_impact	0,11	medium_impact	1,54	0,51	0,8	18,91	16,9	N	0,22	N	0,97	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14009	14009	T	C	MI.22813	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1673	558	L	P	cTa/cCa	-1,21	0	0	probably_damaging	1	neutral	0,23	neutral	0,75	deleterious	-4,02	deleterious	-5,6	medium_impact	3	damaging	0,58	damaging	0,11	deleterious	4,11	23,7	0,12	0,4	disease	0,86	disease	0,74	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	-0,06	medium_impact	1,54	0,48	0,8	18,91	16,9	N	0,23	N	0,91	polymorphism	0,92	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14011	14011	G	C	MI.22814	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1675	559	E	Q	Gaa/Caa	-3,73	0	0	probably_damaging	0,91	neutral	0,36	neutral	-0,25	deleterious	-5,57	deleterious	-2,65	medium_impact	3,48	neutral	0,63	neutral	0,56	deleterious	3,11	22,5	0,34	0,5	disease	0,58	disease	0,62	disease	0,57	disease	0,58	2	neutral	0,92	neutral	0,23	deleterious	1	deleterious	0,66	low_impact	-1,7	medium_impact	0,1	medium_impact	1,98	0,6	0,8	27,86	7,1	N	0,36	N	0,77	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14011	14011	G	A	MI.22815	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1675	559	E	K	Gaa/Aaa	-3,73	0	0	benign	0,22	neutral	0,45	neutral	-0,18	deleterious	-4,14	deleterious	-3,53	medium_impact	2,15	damaging	0,6	neutral	0,54	deleterious	2,71	20,9	0,37	0,5	neutral	0,5	disease	0,56	disease	0,51	neutral	0,44	1	neutral	0,46	deleterious	0,62	neutral	-3	neutral	0,28	medium_impact	-0,22	medium_impact	0,18	medium_impact	0,76	0,62	0,8	27,86	7,1	N	0,33	N	0,35	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14012	14012	A	C	MI.22816	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1676	559	E	A	gAa/gCa	5,9	1	0	possibly_damaging	0,86	neutral	0,61	neutral	-0,26	deleterious	-5,68	deleterious	-5,3	high_impact	3,82	neutral	0,61	neutral	0,61	deleterious	2,11	16,9	0,25	0,45	disease	0,62	disease	0,56	disease	0,66	disease	0,66	3	neutral	0,83	neutral	0,38	deleterious	1	deleterious	0,63	low_impact	-1,5	medium_impact	0,34	high_impact	2,29	0,66	0,8	27,86	7,1	P	0,59	P	0,74	disease_causing	0,97	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14012	14012	A	T	MI.22817	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1676	559	E	V	gAa/gTa	5,9	1	0	probably_damaging	0,97	neutral	0,56	neutral	-0,28	deleterious	-7,1	deleterious	-6,18	high_impact	3,82	damaging	0,59	neutral	0,57	deleterious	4,01	23,6	0,21	0,45	disease	0,73	disease	0,72	disease	0,67	disease	0,68	4	neutral	0,97	neutral	0,3	deleterious	2	deleterious	0,76	low_impact	-2,18	medium_impact	0,29	high_impact	2,29	0,7	0,85	27,86	7,1	P	0,51	P	0,91	disease_causing	0,99	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14012	14012	A	G	MI.22818	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1676	559	E	G	gAa/gGa	5,9	1	0	probably_damaging	0,94	neutral	0,36	neutral	-0,27	deleterious	-6,11	deleterious	-6,18	medium_impact	3,48	damaging	0,59	neutral	0,64	deleterious	3,93	23,5	0,29	0,45	disease	0,7	disease	0,62	disease	0,65	disease	0,66	3	neutral	0,94	neutral	0,21	deleterious	1	deleterious	0,7	low_impact	-1,88	medium_impact	0,1	medium_impact	1,98	0,42	0,8	27,86	7,1	P	0,54	P	0,82	disease_causing	0,97	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14013	14013	A	C	MI.22819	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1677	559	E	D	gaA/gaC	8,42	1	0	possibly_damaging	0,89	neutral	0,26	neutral	-0,21	deleterious	-4,58	deleterious	-2,65	medium_impact	3,48	damaging	0,6	neutral	0,52	deleterious	3,46	23	0,38	0,5	neutral	0,31	disease	0,62	neutral	0,5	neutral	0,49	0	neutral	0,92	neutral	0,19	NA	0	deleterious	0,61	low_impact	-1,61	medium_impact	-0,02	medium_impact	1,98	0,65	0,8	27,86	7,1	P	0,65	P	0,8	disease_causing	0,97	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6094	6094	T	A	MI.2282	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	191	64	V	E	gTa/gAa	1,51	0,97	0	probably_damaging	0,98	deleterious	0,01	neutral	2,68	deleterious	-3,38	deleterious	-3,59	high_impact	3,77	neutral	0,61	neutral	0,49	deleterious	4,39	24,1	0,11	0,55	disease	0,79	disease	0,88	disease	0,7	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-2,35	medium_impact	-0,92	high_impact	2,38	0,5	0,9	12,87	22,39	N	0,46	N	0,84	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14013	14013	A	T	MI.22820	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1677	559	E	D	gaA/gaT	8,42	1	0	possibly_damaging	0,89	neutral	0,26	neutral	-0,21	deleterious	-4,58	deleterious	-2,65	medium_impact	3,48	damaging	0,6	neutral	0,52	deleterious	3,6	23,2	0,38	0,5	neutral	0,31	disease	0,62	neutral	0,5	neutral	0,49	0	neutral	0,92	neutral	0,19	NA	0	deleterious	0,61	low_impact	-1,61	medium_impact	-0,02	medium_impact	1,98	0,65	0,8	27,86	7,1	P	0,66	P	0,8	disease_causing	0,97	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14014	14014	A	G	MI.22821	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1678	560	K	E	Aag/Gag	3,15	0,99	0	probably_damaging	1	neutral	0,34	neutral	0,82	neutral	-2,29	deleterious	-2,91	medium_impact	3,25	neutral	0,73	neutral	0,34	deleterious	4,05	23,7	0,4	0,5	neutral	0,38	disease	0,73	disease	0,57	disease	0,63	3	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,07	medium_impact	1,77	0,7	0,85	17,25	18,6	N	0,46	N	0,77	disease_causing	0,75	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14014	14014	A	C	MI.22822	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1678	560	K	Q	Aag/Cag	3,15	0,99	0	probably_damaging	1	neutral	0,36	neutral	0,82	neutral	-2,18	deleterious	-2,89	medium_impact	3,05	neutral	0,76	neutral	0,37	deleterious	3,43	23	0,46	0,55	disease	0,54	disease	0,62	disease	0,54	disease	0,59	2	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,1	medium_impact	1,58	0,64	0,8	17,25	18,6	N	0,45	N	0,74	disease_causing	0,65	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14015	14015	A	C	MI.22823	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1679	560	K	T	aAg/aCg	1,08	0,47	0	probably_damaging	1	neutral	0,45	neutral	0,84	neutral	-1,7	deleterious	-4,18	medium_impact	2,21	neutral	0,84	neutral	0,96	deleterious	2,48	19,32	0,29	0,45	neutral	0,43	disease	0,52	neutral	0,35	neutral	0,47	1	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,71	low_impact	-3,6	medium_impact	0,18	medium_impact	0,82	0,63	0,8	17,25	18,6	N	0,31	N	0,77	polymorphism	0,64	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14015	14015	A	T	MI.22824	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1679	560	K	M	aAg/aTg	1,08	0,47	0	probably_damaging	1	neutral	0,28	neutral	0,82	neutral	-2,34	deleterious	-4,5	medium_impact	3,25	neutral	0,8	neutral	0,82	deleterious	2,91	21,9	0,28	0,45	disease	0,7	disease	0,59	neutral	0,43	disease	0,53	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,01	medium_impact	1,77	0,48	0,8	17,25	18,6	N	0,33	N	0,83	disease_causing	0,56	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14016	14016	G	C	MI.22825	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1680	560	K	N	aaG/aaC	0,63	0,06	0,02	probably_damaging	1	neutral	0,37	neutral	0,86	neutral	-1,34	deleterious	-3,02	medium_impact	2,08	neutral	0,82	neutral	0,98	deleterious	2,77	21,2	0,56	0,6	disease	0,51	neutral	0,45	neutral	0,33	neutral	0,27	5	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,11	medium_impact	0,7	0,74	0,85	17,25	18,6	N	0,4	N	0,55	polymorphism	0,96	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14016	14016	G	T	MI.22826	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1680	560	K	N	aaG/aaT	0,63	0,06	0,02	probably_damaging	1	neutral	0,37	neutral	0,86	neutral	-1,34	deleterious	-3,02	medium_impact	2,08	neutral	0,82	neutral	0,98	deleterious	2,91	21,9	0,56	0,6	disease	0,51	neutral	0,45	neutral	0,33	neutral	0,27	5	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,11	medium_impact	0,7	0,74	0,85	17,25	18,6	N	0,4	N	0,55	polymorphism	0,96	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14017	14017	C	A	MI.22827	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1681	561	L	M	Cta/Ata	-2,35	0	0	possibly_damaging	0,9	neutral	0,23	neutral	0,91	neutral	-0,65	neutral	-0,05	neutral_impact	0,34	neutral	0,81	neutral	0,97	deleterious	2,68	20,7	0,35	0,5	neutral	0,49	neutral	0,07	neutral	0,17	neutral	0,26	5	neutral	0,93	neutral	0,17	neutral	-3	deleterious	0,64	low_impact	-1,65	medium_impact	-0,06	medium_impact	-0,89	0,77	0,85	27,53	21,87	P	0,59	P	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14017	14017	C	G	MI.22828	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1681	561	L	V	Cta/Gta	-2,35	0	0	benign	0,27	neutral	0,52	neutral	0,94	neutral	-0,38	neutral	0,36	neutral_impact	0,75	neutral	0,84	neutral	0,98	deleterious	0,85	9,76	0,35	0,5	neutral	0,34	neutral	0,07	neutral	0,14	neutral	0,31	4	neutral	0,38	deleterious	0,63	neutral	-6	deleterious	0,49	medium_impact	-0,34	medium_impact	0,25	medium_impact	-0,52	0,56	0,8	27,53	21,87	N	0,48	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14018	14018	T	G	MI.22829	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1682	561	L	R	cTa/cGa	-7,62	0	0	possibly_damaging	0,66	neutral	0,37	neutral	0,77	deleterious	-3,48	neutral	-1,77	medium_impact	2,13	neutral	0,74	neutral	0,5	deleterious	4,26	23,9	0,23	0,45	disease	0,66	disease	0,54	disease	0,51	disease	0,56	1	neutral	0,7	neutral	0,36	NA	0	deleterious	0,74	low_impact	-1,02	medium_impact	0,11	medium_impact	0,74	0,53	0,8	27,53	21,87	N	0,28	N	0,49	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6094	6094	T	G	MI.2283	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	191	64	V	G	gTa/gGa	1,51	0,97	0	probably_damaging	0,99	deleterious	0	neutral	2,69	deleterious	-3,18	deleterious	-4,23	high_impact	4,12	neutral	0,63	neutral	0,6	deleterious	3,58	23,2	0,17	0,55	disease	0,58	disease	0,79	disease	0,59	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	2,71	0,52	0,9	12,87	22,39	N	0,45	N	0,71	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14018	14018	T	C	MI.22830	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1682	561	L	P	cTa/cCa	-7,62	0	0	possibly_damaging	0,66	neutral	0,23	neutral	0,76	deleterious	-4,05	neutral	-1,84	medium_impact	2,13	neutral	0,64	neutral	0,41	deleterious	2,89	21,8	0,18	0,45	disease	0,84	disease	0,65	disease	0,55	disease	0,7	4	neutral	0,8	neutral	0,29	NA	0	deleterious	0,81	low_impact	-1,02	medium_impact	-0,06	medium_impact	0,74	0,48	0,8	27,53	21,87	N	0,3	N	0,68	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14018	14018	T	A	MI.22831	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1682	561	L	Q	cTa/cAa	-7,62	0	0	possibly_damaging	0,66	neutral	0,33	neutral	0,77	deleterious	-3,66	neutral	-1,47	medium_impact	2,13	neutral	0,81	neutral	0,6	deleterious	4,18	23,8	0,22	0,45	disease	0,8	neutral	0,34	neutral	0,38	disease	0,62	2	neutral	0,73	neutral	0,34	NA	0	deleterious	0,73	low_impact	-1,02	medium_impact	0,06	medium_impact	0,74	0,48	0,8	27,53	21,87	N	0,32	N	0,46	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14020	14020	T	G	MI.22832	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1684	562	L	V	Tta/Gta	-20	0	0	possibly_damaging	0,44	neutral	0,57	neutral	0,99	neutral	-0,19	neutral	-0,3	low_impact	1,2	neutral	0,78	neutral	0,66	deleterious	0,39	6,56	0,55	0,6	neutral	0,32	neutral	0,39	disease	0,54	neutral	0,45	1	neutral	0,41	deleterious	0,57	neutral	-3	deleterious	0,45	medium_impact	-0,65	medium_impact	0,3	medium_impact	-0,11	0,44	0,8	32,17	26,19	N	0,28	N	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14020	14020	T	A	MI.22833	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1684	562	L	M	Tta/Ata	-20	0	0	benign	0,06	neutral	0,3	neutral	0,96	neutral	-0,82	neutral	-0,24	neutral_impact	0,16	neutral	0,83	neutral	0,88	deleterious	0,47	7,2	0,41	0,5	disease	0,64	neutral	0,3	neutral	0,22	disease	0,6	2	neutral	0,67	deleterious	0,62	neutral	-6	neutral	0,28	medium_impact	0,39	medium_impact	0,03	low_impact	-1,06	0,69	0,85	32,17	26,19	N	0,4	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14021	14021	T	G	MI.22834	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1685	562	L	W	tTa/tGa	-0,06	0	0	probably_damaging	0,97	neutral	0,23	neutral	0,92	neutral	-2,47	deleterious	-3,64	low_impact	1,2	neutral	0,68	neutral	0,46	deleterious	3,81	23,4	0,21	0,45	disease	0,9	disease	0,7	disease	0,59	disease	0,79	6	neutral	0,98	neutral	0,13	neutral	-2	deleterious	0,84	low_impact	-2,18	medium_impact	-0,06	medium_impact	-0,11	0,54	0,8	32,17	26,19	N	0,27	N	0,61	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14021	14021	T	C	MI.22835	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1685	562	L	S	tTa/tCa	-0,06	0	0	possibly_damaging	0,71	neutral	0,53	neutral	1	neutral	-0,07	deleterious	-2,63	neutral_impact	0,57	neutral	0,7	neutral	0,81	deleterious	3,63	23,2	0,34	0,5	disease	0,63	neutral	0,5	disease	0,57	disease	0,66	3	neutral	0,68	neutral	0,41	neutral	-3	deleterious	0,67	low_impact	-1,12	medium_impact	0,26	medium_impact	-0,68	0,59	0,8	32,17	26,19	N	0,26	N	0,35	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14022	14022	A	T	MI.22836	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1686	562	L	F	ttA/ttT	2,92	0,21	0	possibly_damaging	0,69	neutral	0,71	neutral	0,94	neutral	-1,49	neutral	-2,02	low_impact	1,2	neutral	0,64	neutral	0,55	deleterious	2,1	16,84	0,48	0,55	disease	0,63	disease	0,51	disease	0,55	disease	0,67	3	neutral	0,62	deleterious	0,51	neutral	-3	deleterious	0,66	low_impact	-1,08	medium_impact	0,45	medium_impact	-0,11	0,56	0,8	32,17	26,19	N	0,28	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14022	14022	A	C	MI.22837	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1686	562	L	F	ttA/ttC	2,92	0,21	0	possibly_damaging	0,69	neutral	0,71	neutral	0,94	neutral	-1,49	neutral	-2,02	low_impact	1,2	neutral	0,64	neutral	0,55	deleterious	1,96	15,97	0,48	0,55	disease	0,63	disease	0,51	disease	0,55	disease	0,67	3	neutral	0,62	deleterious	0,51	neutral	-3	deleterious	0,66	low_impact	-1,08	medium_impact	0,45	medium_impact	-0,11	0,56	0,8	32,17	26,19	N	0,28	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14023	14023	C	A	MI.22838	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1687	563	P	T	Cct/Act	-4,87	0	0	probably_damaging	1	neutral	0,4	neutral	0,56	deleterious	-3,46	deleterious	-7,05	medium_impact	3,34	damaging	0,58	damaging	0,06	deleterious	3,88	23,5	0,39	0,5	disease	0,54	disease	0,71	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,14	medium_impact	1,85	0,65	0,8	29,35	7,05	N	0,22	N	0,91	polymorphism	0,97	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14023	14023	C	G	MI.22839	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1687	563	P	A	Cct/Gct	-4,87	0	0	probably_damaging	1	neutral	0,51	neutral	0,67	neutral	-1,72	deleterious	-7,05	medium_impact	3,08	damaging	0,55	damaging	0,12	deleterious	3,24	22,8	0,41	0,5	disease	0,52	disease	0,51	disease	0,66	neutral	0,49	0	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,24	medium_impact	1,61	0,68	0,85	29,35	7,05	N	0,24	N	0,73	polymorphism	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6094	6094	T	C	MI.2284	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	191	64	V	A	gTa/gCa	1,51	0,97	0	possibly_damaging	0,58	deleterious	0	neutral	2,8	neutral	-1,23	neutral	-2,34	medium_impact	2,8	neutral	0,67	neutral	0,6	deleterious	3,1	22,5	0,29	0,55	disease	0,52	disease	0,58	disease	0,57	disease	0,69	4	deleterious	1	neutral	0,21	deleterious	4	deleterious	0,45	medium_impact	-0,89	low_impact	-1,48	medium_impact	1,49	0,58	0,9	12,87	22,39	N	0,44	N	0,47	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14023	14023	C	T	MI.22840	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1687	563	P	S	Cct/Tct	-4,87	0	0	probably_damaging	1	neutral	0,41	neutral	0,64	neutral	-2,09	deleterious	-7,05	medium_impact	3,34	damaging	0,57	damaging	0,08	deleterious	4,07	23,7	0,49	0,55	neutral	0,48	disease	0,72	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,15	medium_impact	1,85	0,21	0,8	29,35	7,05	N	0,22	N	0,78	polymorphism	0,97	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14024	14024	C	G	MI.22841	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1688	563	P	R	cCt/cGt	7,04	1	0	probably_damaging	1	neutral	0,35	neutral	0,53	deleterious	-4,51	deleterious	-7,94	medium_impact	3,19	damaging	0,54	damaging	0,09	deleterious	3,7	23,3	0,44	0,55	neutral	0,45	disease	0,8	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,79	low_impact	-3,6	medium_impact	0,08	medium_impact	1,71	0,67	0,85	29,35	7,05	P	0,49	N	0,64	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14024	14024	C	T	MI.22842	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1688	563	P	L	cCt/cTt	7,04	1	0	probably_damaging	1	neutral	0,66	neutral	0,53	deleterious	-4,29	deleterious	-8,81	high_impact	3,88	damaging	0,56	damaging	0,06	deleterious	4,43	24,2	0,39	0,5	disease	0,65	disease	0,78	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,39	high_impact	2,34	0,8	0,85	29,35	7,05	N	0,47	N	0,97	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14024	14024	C	A	MI.22843	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1688	563	P	H	cCt/cAt	7,04	1	0	probably_damaging	1	neutral	0,54	neutral	0,52	deleterious	-5,52	deleterious	-7,94	high_impact	3,88	damaging	0,59	damaging	0,07	deleterious	4,21	23,9	0,46	0,55	disease	0,75	disease	0,79	disease	0,77	disease	0,77	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,27	high_impact	2,34	0,7	0,85	29,35	7,05	P	0,54	P	0,72	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14026	14026	A	C	MI.22844	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1690	564	K	Q	Aaa/Caa	-6,94	0	0	probably_damaging	1	neutral	0,31	neutral	0,99	neutral	-0,05	deleterious	-3,53	medium_impact	2,1	neutral	0,73	neutral	0,59	deleterious	3,51	23,1	0,63	0,7	neutral	0,4	disease	0,61	neutral	0,34	neutral	0,45	1	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	0,04	medium_impact	0,72	0,68	0,85	9,62	6,96	N	0,38	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14026	14026	A	G	MI.22845	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1690	564	K	E	Aaa/Gaa	-6,94	0	0	probably_damaging	1	neutral	0,3	neutral	0,83	neutral	-1,1	deleterious	-3,53	medium_impact	2,21	neutral	0,7	neutral	0,67	deleterious	4,17	23,8	0,39	0,5	neutral	0,42	disease	0,64	neutral	0,48	neutral	0,46	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,03	medium_impact	0,82	0,55	0,8	9,62	6,96	N	0,32	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14027	14027	A	T	MI.22846	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1691	564	K	M	aAa/aTa	4,06	0,99	0	probably_damaging	1	neutral	0,23	neutral	0,69	deleterious	-4,44	deleterious	-5,26	medium_impact	2,46	neutral	0,79	neutral	0,74	deleterious	4,15	23,8	0,3	0,45	disease	0,67	disease	0,68	disease	0,54	disease	0,56	1	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	-0,06	medium_impact	1,04	0,43	0,8	9,62	6,96	N	0,43	N	0,4	polymorphism	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14027	14027	A	C	MI.22847	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1691	564	K	T	aAa/aCa	4,06	0,99	0	probably_damaging	1	neutral	0,42	neutral	0,74	neutral	-2,32	deleterious	-5,3	medium_impact	2,63	neutral	0,74	neutral	0,7	deleterious	3,82	23,4	0,32	0,5	disease	0,58	disease	0,67	disease	0,64	disease	0,62	2	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,16	medium_impact	1,2	0,54	0,8	9,62	6,96	N	0,44	N	0,75	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14028	14028	A	T	MI.22848	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1692	564	K	N	aaA/aaT	4,29	0,99	0	probably_damaging	1	neutral	0,32	neutral	0,74	neutral	-2,3	deleterious	-4,42	medium_impact	2,8	neutral	0,79	neutral	0,68	deleterious	4,03	23,6	0,65	0,7	disease	0,62	disease	0,69	disease	0,65	disease	0,63	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,05	medium_impact	1,36	0,81	0,85	9,62	6,96	N	0,47	N	0,63	polymorphism	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14028	14028	A	C	MI.22849	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1692	564	K	N	aaA/aaC	4,29	0,99	0	probably_damaging	1	neutral	0,32	neutral	0,74	neutral	-2,3	deleterious	-4,42	medium_impact	2,8	neutral	0,79	neutral	0,68	deleterious	3,98	23,6	0,65	0,7	disease	0,62	disease	0,69	disease	0,65	disease	0,63	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,05	medium_impact	1,36	0,81	0,85	9,62	6,96	N	0,44	N	0,63	polymorphism	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6096	6096	A	G	MI.2285	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	193	65	M	V	Ata/Gta	-4,5	0	0	probably_damaging	0,94	deleterious	0	neutral	2,53	neutral	-1,47	deleterious	-2,55	high_impact	4,83	damaging	0,5	damaging	0,13	deleterious	2,64	20,5	0,41	0,55	disease	0,74	disease	0,9	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,83	low_impact	-1,88	low_impact	-1,48	high_impact	3,36	0,33	0,9	3,12	7,58	P	0,67	P	0,88	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14029	14029	A	T	MI.22850	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1693	565	T	S	Aca/Tca	-0,06	0	0	benign	0,36	neutral	0,47	neutral	1,02	neutral	0,34	neutral	0,12	neutral_impact	0	neutral	0,84	neutral	0,99	neutral	-0,27	0,78	0,53	0,6	neutral	0,32	neutral	0,14	neutral	0,21	neutral	0,31	4	neutral	0,45	deleterious	0,56	neutral	-6	deleterious	0,48	medium_impact	-0,51	medium_impact	0,2	low_impact	-1,2	0,72	0,85	32,17	20,58	N	0,45	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14029	14029	A	C	MI.22851	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1693	565	T	P	Aca/Cca	-0,06	0	0	possibly_damaging	0,75	neutral	0,26	neutral	0,94	neutral	-1,88	neutral	-2,22	low_impact	1,15	neutral	0,78	neutral	0,37	deleterious	3,44	23	0,17	0,45	disease	0,51	disease	0,66	disease	0,67	disease	0,74	5	neutral	0,83	neutral	0,26	neutral	-3	deleterious	0,74	low_impact	-1,2	medium_impact	-0,02	medium_impact	-0,15	0,59	0,8	32,17	20,58	N	0,25	N	0,73	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14029	14029	A	G	MI.22852	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1693	565	T	A	Aca/Gca	-0,06	0	0	benign	0,01	neutral	0,53	neutral	1,04	neutral	0,54	neutral	-1,13	neutral_impact	0,05	neutral	0,86	neutral	0,87	neutral	-0,19	1,17	0,65	0,7	neutral	0,46	neutral	0,07	neutral	0,2	neutral	0,3	4	neutral	0,45	deleterious	0,76	neutral	-6	neutral	0,16	medium_impact	1,15	medium_impact	0,26	low_impact	-1,16	0,49	0,8	32,17	20,58	N	0,39	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14030	14030	C	A	MI.22853	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1694	565	T	K	aCa/aAa	-0,52	0	0	possibly_damaging	0,56	neutral	0,32	neutral	1,01	neutral	0,1	neutral	-1,37	low_impact	1,15	neutral	0,73	neutral	0,45	deleterious	4,31	24	0,3	0,45	neutral	0,42	neutral	0,42	disease	0,64	neutral	0,5	0	neutral	0,68	neutral	0,38	neutral	-3	deleterious	0,62	medium_impact	-0,85	medium_impact	0,05	medium_impact	-0,15	0,77	0,85	32,17	20,58	N	0,36	N	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14030	14030	C	T	MI.22854	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1694	565	T	M	aCa/aTa	-0,52	0	0	benign	0,08	neutral	0,27	neutral	0,97	neutral	-0,8	neutral	-1,38	neutral_impact	-0,24	neutral	0,86	neutral	0,77	deleterious	2,75	21,1	0,36	0,5	disease	0,78	neutral	0,22	neutral	0,24	disease	0,53	1	neutral	0,7	deleterious	0,6	neutral	-6	deleterious	0,72	medium_impact	0,26	medium_impact	-0,01	low_impact	-1,42	0,73	0,85	32,17	20,58	N	0,4	N	0,31	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14032	14032	A	G	MI.22855	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1696	566	I	V	Att/Gtt	-4,42	0	0	benign	0,09	neutral	0,52	neutral	0,87	neutral	-0,9	neutral	-0,48	low_impact	1,23	neutral	0,85	neutral	0,93	neutral	1,61	13,92	0,71	0,75	neutral	0,33	neutral	0,1	neutral	0,31	neutral	0,31	4	neutral	0,4	deleterious	0,72	neutral	-6	deleterious	0,62	medium_impact	0,21	medium_impact	0,25	medium_impact	-0,08	0,4	0,8	25,37	16,95	N	0,4	N	0,68	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14032	14032	A	T	MI.22856	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1696	566	I	F	Att/Ttt	-4,42	0	0	probably_damaging	0,91	neutral	0,72	neutral	0,79	neutral	-1,87	neutral	-2,44	low_impact	1,71	neutral	0,71	neutral	0,63	deleterious	4,21	23,9	0,4	0,5	neutral	0,46	neutral	0,45	disease	0,53	disease	0,52	0	neutral	0,89	neutral	0,41	neutral	-2	deleterious	0,7	low_impact	-1,7	medium_impact	0,46	medium_impact	0,36	0,62	0,8	25,37	16,95	N	0,24	N	0,69	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14032	14032	A	C	MI.22857	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1696	566	I	L	Att/Ctt	-4,42	0	0	benign	0,3	neutral	0,7	neutral	1,05	neutral	0,26	neutral	-0,24	neutral_impact	0,02	neutral	0,79	neutral	0,97	neutral	1,62	13,96	0,45	0,55	neutral	0,37	neutral	0,09	neutral	0,19	neutral	0,27	5	neutral	0,23	deleterious	0,7	neutral	-6	deleterious	0,64	medium_impact	-0,4	medium_impact	0,44	low_impact	-1,18	0,74	0,85	25,37	16,95	N	0,44	N	0,61	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14033	14033	T	G	MI.22858	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1697	566	I	S	aTt/aGt	-0,06	0	0	possibly_damaging	0,66	neutral	0,44	neutral	0,76	neutral	-2,46	deleterious	-3,38	medium_impact	2,2	neutral	0,77	neutral	0,57	deleterious	4,44	24,2	0,28	0,45	neutral	0,49	disease	0,56	disease	0,66	disease	0,72	4	neutral	0,66	neutral	0,39	NA	0	deleterious	0,76	low_impact	-1,02	medium_impact	0,18	medium_impact	0,81	0,6	0,8	25,37	16,95	N	0,27	N	0,7	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14033	14033	T	A	MI.22859	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1697	566	I	N	aTt/aAt	-0,06	0	0	probably_damaging	0,91	neutral	0,33	neutral	0,72	deleterious	-3,95	deleterious	-4,35	medium_impact	2,75	neutral	0,74	neutral	0,43	deleterious	4,81	24,8	0,3	0,45	disease	0,76	disease	0,61	disease	0,65	disease	0,73	5	neutral	0,92	neutral	0,21	deleterious	1	deleterious	0,8	low_impact	-1,7	medium_impact	0,06	medium_impact	1,31	0,56	0,8	25,37	16,95	N	0,29	N	0,88	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6096	6096	A	C	MI.2286	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	193	65	M	L	Ata/Cta	-4,5	0	0	probably_damaging	0,91	deleterious	0	neutral	2,58	neutral	-1,1	neutral	-1,92	high_impact	4,62	damaging	0,58	damaging	0,1	deleterious	3,16	22,6	0,31	0,55	disease	0,71	disease	0,82	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,76	low_impact	-1,7	low_impact	-1,48	high_impact	3,17	0,37	0,9	3,12	7,58	N	0,45	N	0,61	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14033	14033	T	C	MI.22860	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1697	566	I	T	aTt/aCt	-0,06	0	0	benign	0,09	neutral	0,43	neutral	0,79	neutral	-1,8	neutral	-2,19	neutral_impact	0,7	neutral	0,86	neutral	0,99	deleterious	1,9	15,58	0,45	0,55	neutral	0,39	neutral	0,26	neutral	0,36	neutral	0,44	1	neutral	0,51	deleterious	0,67	neutral	-6	deleterious	0,7	medium_impact	0,21	medium_impact	0,17	medium_impact	-0,56	0,63	0,8	25,37	16,95	N	0,38	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	COSM488754	.	.	.	.	.	.	.	.
chrM	14034	14034	T	G	MI.22861	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1698	566	I	M	atT/atG	1,54	0	0	probably_damaging	0,95	neutral	0,25	neutral	0,79	neutral	-1,8	neutral	-1,07	low_impact	1,43	neutral	0,83	neutral	0,95	deleterious	2,4	18,83	0,51	0,6	disease	0,58	neutral	0,21	neutral	0,28	neutral	0,46	1	neutral	0,96	neutral	0,15	neutral	-2	deleterious	0,7	low_impact	-1,96	medium_impact	-0,03	medium_impact	0,1	0,75	0,85	25,37	16,95	N	0,44	N	0,69	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14034	14034	T	A	MI.22862	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1698	566	I	M	atT/atA	1,54	0	0	probably_damaging	0,95	neutral	0,25	neutral	0,79	neutral	-1,8	neutral	-1,07	low_impact	1,43	neutral	0,83	neutral	0,95	deleterious	2,65	20,5	0,51	0,6	disease	0,58	neutral	0,21	neutral	0,28	neutral	0,46	1	neutral	0,96	neutral	0,15	neutral	-2	deleterious	0,7	low_impact	-1,96	medium_impact	-0,03	medium_impact	0,1	0,75	0,85	25,37	16,95	N	0,44	N	0,69	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14035	14035	T	G	MI.22863	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1699	567	S	A	Tca/Gca	-6,25	0	0	benign	0,01	neutral	0,59	neutral	1,11	neutral	0,96	neutral	-0,46	neutral_impact	-0,42	neutral	0,82	neutral	0,99	neutral	1,57	13,67	0,46	0,55	neutral	0,45	neutral	0,06	neutral	0,19	neutral	0,24	5	neutral	0,39	deleterious	0,79	neutral	-6	deleterious	0,68	medium_impact	1,15	medium_impact	0,32	low_impact	-1,59	0,52	0,8	15,09	12,11	N	0,43	N	0,37	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14035	14035	T	C	MI.22864	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1699	567	S	P	Tca/Cca	-6,25	0	0	possibly_damaging	0,8	neutral	0,21	neutral	0,9	neutral	-2,62	deleterious	-3,19	low_impact	1,67	neutral	0,66	neutral	0,62	deleterious	4,12	23,8	0,22	0,45	disease	0,73	disease	0,75	disease	0,61	disease	0,7	4	neutral	0,88	neutral	0,21	neutral	-3	deleterious	0,83	low_impact	-1,32	medium_impact	-0,09	medium_impact	0,32	0,44	0,8	15,09	12,11	N	0,28	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14035	14035	T	A	MI.22865	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1699	567	S	T	Tca/Aca	-6,25	0	0	benign	0,04	neutral	0,44	neutral	0,96	neutral	-0,59	neutral	-1,46	neutral_impact	-0,11	neutral	0,89	neutral	0,98	deleterious	2,24	17,8	0,4	0,5	neutral	0,49	neutral	0,15	neutral	0,21	neutral	0,27	5	neutral	0,52	deleterious	0,7	neutral	-6	deleterious	0,68	medium_impact	0,57	medium_impact	0,18	low_impact	-1,3	0,63	0,8	15,09	12,11	N	0,37	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14036	14036	C	T	MI.22866	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1700	567	S	L	tCa/tTa	-2,35	0	0	benign	0,24	neutral	0,81	neutral	0,98	neutral	-0,2	deleterious	-3,59	low_impact	1,67	neutral	0,78	neutral	0,61	deleterious	4,73	24,6	0,37	0,5	disease	0,57	disease	0,53	neutral	0,45	neutral	0,5	0	neutral	0,14	deleterious	0,79	neutral	-6	deleterious	0,74	medium_impact	-0,27	medium_impact	0,58	medium_impact	0,32	0,77	0,85	15,09	12,11	N	0,2	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14036	14036	C	G	MI.22867	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1700	567	S	W	tCa/tGa	-2,35	0	0	probably_damaging	0,95	neutral	0,21	neutral	0,9	neutral	-2,83	deleterious	-4,85	medium_impact	2,48	neutral	0,77	neutral	0,42	deleterious	4,48	24,2	0,18	0,45	disease	0,73	disease	0,73	disease	0,64	disease	0,73	5	neutral	0,97	neutral	0,13	deleterious	1	deleterious	0,8	low_impact	-1,96	medium_impact	-0,09	medium_impact	1,06	0,5	0,8	15,09	12,11	N	0,27	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14038	14038	C	A	MI.22868	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1702	568	Q	K	Cag/Aag	-6,02	0	0	possibly_damaging	0,44	neutral	0,3	neutral	1,11	neutral	1,21	neutral	-0,67	neutral_impact	0,26	neutral	0,82	neutral	0,88	deleterious	0,49	7,35	0,55	0,6	neutral	0,35	neutral	0,16	neutral	0,46	neutral	0,29	4	neutral	0,66	neutral	0,43	neutral	-3	deleterious	0,44	medium_impact	-0,65	medium_impact	0,03	medium_impact	-0,97	0,66	0,8	31,67	22,55	N	0,37	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14038	14038	C	G	MI.22869	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1702	568	Q	E	Cag/Gag	-6,02	0	0	benign	0,36	neutral	0,27	neutral	1,06	neutral	0,71	neutral	-0,54	low_impact	0,92	neutral	0,85	neutral	0,64	neutral	-0,51	0,21	0,51	0,6	neutral	0,43	neutral	0,21	neutral	0,41	neutral	0,39	2	neutral	0,68	neutral	0,46	neutral	-6	neutral	0,37	medium_impact	-0,51	medium_impact	-0,01	medium_impact	-0,36	0,57	0,8	31,67	22,55	N	0,37	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6096	6096	A	T	MI.2287	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	193	65	M	L	Ata/Tta	-4,5	0	0	probably_damaging	0,91	deleterious	0	neutral	2,58	neutral	-1,1	neutral	-1,92	high_impact	4,62	damaging	0,58	damaging	0,1	deleterious	3,25	22,8	0,31	0,55	disease	0,71	disease	0,82	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,76	low_impact	-1,7	low_impact	-1,48	high_impact	3,17	0,37	0,9	3,12	7,58	N	0,45	N	0,61	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14039	14039	A	C	MI.22870	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1703	568	Q	P	cAg/cCg	-6,71	0	0	possibly_damaging	0,86	neutral	0,23	neutral	0,94	neutral	-1,54	neutral	-1,86	low_impact	1,54	neutral	0,75	neutral	0,63	neutral	1,74	14,66	0,17	0,45	disease	0,63	disease	0,53	disease	0,6	disease	0,72	4	neutral	0,91	neutral	0,19	neutral	-3	deleterious	0,72	low_impact	-1,5	medium_impact	-0,06	medium_impact	0,2	0,56	0,8	31,67	22,55	N	0,33	N	0,81	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14039	14039	A	G	MI.22871	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1703	568	Q	R	cAg/cGg	-6,71	0	0	possibly_damaging	0,48	neutral	0,35	neutral	0,99	neutral	-0,19	neutral	-0,79	low_impact	1,34	neutral	0,82	neutral	0,63	neutral	-0,09	1,78	0,56	0,6	neutral	0,47	neutral	0,21	neutral	0,46	neutral	0,37	3	neutral	0,62	neutral	0,44	neutral	-3	deleterious	0,44	medium_impact	-0,71	medium_impact	0,08	medium_impact	0,02	0,46	0,8	31,67	22,55	N	0,38	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14039	14039	A	T	MI.22872	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1703	568	Q	L	cAg/cTg	-6,71	0	0	possibly_damaging	0,48	neutral	0,84	neutral	0,97	neutral	-0,49	neutral	-1,65	neutral_impact	0,74	neutral	0,82	neutral	0,98	neutral	-0,13	1,54	0,45	0,55	neutral	0,27	neutral	0,16	neutral	0,24	neutral	0,25	5	neutral	0,38	deleterious	0,68	neutral	-3	deleterious	0,5	medium_impact	-0,71	medium_impact	0,63	medium_impact	-0,53	0,31	0,8	31,67	22,55	N	0,31	N	0,24	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14040	14040	G	T	MI.22873	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1704	568	Q	H	caG/caT	-2,81	0	0,02	benign	0,03	neutral	0,55	neutral	0,95	neutral	-1,25	neutral	-0,18	neutral_impact	0,65	neutral	0,87	neutral	0,98	neutral	-0,24	0,89	0,62	0,65	disease	0,58	neutral	0,11	neutral	0,26	neutral	0,32	4	neutral	0,42	deleterious	0,76	neutral	-6	neutral	0,15	medium_impact	0,69	medium_impact	0,28	medium_impact	-0,61	0,69	0,85	31,67	22,55	N	0,39	N	0,37	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14040	14040	G	C	MI.22874	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1704	568	Q	H	caG/caC	-2,81	0	0,02	benign	0,03	neutral	0,55	neutral	0,95	neutral	-1,25	neutral	-0,18	neutral_impact	0,65	neutral	0,87	neutral	0,98	neutral	-0,34	0,53	0,62	0,65	disease	0,58	neutral	0,11	neutral	0,26	neutral	0,32	4	neutral	0,42	deleterious	0,76	neutral	-6	neutral	0,15	medium_impact	0,69	medium_impact	0,28	medium_impact	-0,61	0,69	0,85	31,67	22,55	N	0,39	N	0,37	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14041	14041	C	G	MI.22875	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1705	569	H	D	Cac/Gac	-11,29	0	0	benign	0,2	neutral	0,42	neutral	0,99	neutral	-0,32	neutral	-0,69	low_impact	1,04	neutral	0,8	neutral	0,53	deleterious	2,24	17,76	0,29	0,45	disease	0,51	neutral	0,24	disease	0,69	neutral	0,48	0	neutral	0,49	deleterious	0,61	neutral	-6	deleterious	0,54	medium_impact	-0,17	medium_impact	0,16	medium_impact	-0,25	0,59	0,8	27,2	16,62	N	0,3	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14041	14041	C	T	MI.22876	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1705	569	H	Y	Cac/Tac	-11,29	0	0	benign	0,01	neutral	1	neutral	1,02	neutral	0,66	neutral	0,92	neutral_impact	0,69	neutral	0,87	neutral	0,87	neutral	-0,84	0,04	0,68	0,7	disease	0,66	neutral	0,16	disease	0,54	neutral	0,35	3	neutral	0,01	deleterious	1	neutral	-6	neutral	0,16	medium_impact	1,15	high_impact	1,89	medium_impact	-0,57	0,39	0,8	27,2	16,62	N	0,3	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14041	14041	C	A	MI.22877	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1705	569	H	N	Cac/Aac	-11,29	0	0	benign	0,15	neutral	0,48	neutral	1,05	neutral	1,45	neutral	0,09	neutral_impact	0,06	neutral	0,8	neutral	0,9	deleterious	2,18	17,4	0,66	0,7	disease	0,56	neutral	0,09	neutral	0,37	neutral	0,29	4	neutral	0,43	deleterious	0,67	neutral	-6	deleterious	0,5	medium_impact	-0,03	medium_impact	0,21	low_impact	-1,15	0,61	0,8	27,2	16,62	N	0,4	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14042	14042	A	G	MI.22878	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1706	569	H	R	cAc/cGc	-5,33	0	0	benign	0,2	neutral	0,53	neutral	1,01	neutral	0,21	neutral	-0,03	neutral_impact	0,69	neutral	0,79	neutral	0,58	deleterious	-0,02	2,4	0,69	0,75	disease	0,55	neutral	0,16	disease	0,6	neutral	0,31	4	neutral	0,36	deleterious	0,67	neutral	-6	deleterious	0,52	medium_impact	-0,17	medium_impact	0,26	medium_impact	-0,57	0,41	0,8	27,2	16,62	N	0,28	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14042	14042	A	T	MI.22879	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1706	569	H	L	cAc/cTc	-5,33	0	0	benign	0,03	neutral	0,76	neutral	1,15	neutral	2,56	neutral	2,31	neutral_impact	-1,54	neutral	0,82	neutral	0,95	deleterious	0,03	2,88	0,36	0,5	neutral	0,38	neutral	0,11	neutral	0,45	neutral	0,3	4	neutral	0,18	deleterious	0,87	neutral	-6	neutral	0,35	medium_impact	0,69	medium_impact	0,51	low_impact	-2,61	0,29	0,8	27,2	16,62	N	0,28	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6097	6097	T	C	MI.2288	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	194	65	M	T	aTa/aCa	7,07	1	0	probably_damaging	0,99	deleterious	0	neutral	2,4	deleterious	-3,43	deleterious	-3,82	high_impact	4,83	neutral	0,62	damaging	0,11	deleterious	2,88	21,7	0,36	0,55	disease	0,72	disease	0,87	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,64	low_impact	-1,48	high_impact	3,36	0,32	0,9	3,12	7,58	P	0,73	P	0,79	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14042	14042	A	C	MI.22880	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1706	569	H	P	cAc/cCc	-5,33	0	0	benign	0,36	neutral	0,31	neutral	0,99	neutral	-0,74	neutral	-0,58	low_impact	1,04	neutral	0,68	neutral	0,58	deleterious	1,93	15,77	0,25	0,45	disease	0,6	neutral	0,48	disease	0,72	disease	0,63	3	neutral	0,63	deleterious	0,48	neutral	-6	deleterious	0,7	medium_impact	-0,51	medium_impact	0,04	medium_impact	-0,25	0,36	0,8	27,2	16,62	N	0,34	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14043	14043	C	G	MI.22881	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1707	569	H	Q	caC/caG	-1,44	0	0	benign	0,36	neutral	0,5	neutral	1,03	neutral	0,99	neutral	0,24	neutral_impact	-0,7	neutral	0,81	neutral	0,87	deleterious	1,86	15,32	0,6	0,65	neutral	0,45	neutral	0,08	neutral	0,31	neutral	0,25	5	neutral	0,42	deleterious	0,57	neutral	-6	deleterious	0,51	medium_impact	-0,51	medium_impact	0,23	low_impact	-1,84	0,5	0,8	27,2	16,62	N	0,38	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14043	14043	C	A	MI.22882	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1707	569	H	Q	caC/caA	-1,44	0	0	benign	0,36	neutral	0,5	neutral	1,03	neutral	0,99	neutral	0,24	neutral_impact	-0,7	neutral	0,81	neutral	0,87	deleterious	2,2	17,51	0,6	0,65	neutral	0,45	neutral	0,08	neutral	0,31	neutral	0,25	5	neutral	0,42	deleterious	0,57	neutral	-6	deleterious	0,51	medium_impact	-0,51	medium_impact	0,23	low_impact	-1,84	0,5	0,8	27,2	16,62	N	0,37	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14044	14044	C	G	MI.22883	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1708	570	Q	E	Caa/Gaa	-8,54	0	0	possibly_damaging	0,45	neutral	0,28	neutral	0,87	neutral	-1,95	neutral	-1,71	medium_impact	2,96	neutral	0,78	neutral	0,43	deleterious	3,16	22,6	0,53	0,6	neutral	0,37	neutral	0,46	neutral	0,47	neutral	0,5	0	neutral	0,68	neutral	0,42	NA	0	deleterious	0,72	medium_impact	-0,66	medium_impact	0,01	medium_impact	1,5	0,59	0,8	15,42	14,21	N	0,37	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14044	14044	C	A	MI.22884	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1708	570	Q	K	Caa/Aaa	-8,54	0	0	possibly_damaging	0,45	neutral	0,32	neutral	0,88	neutral	-1,85	neutral	-2,3	medium_impact	2,96	neutral	0,76	neutral	0,55	deleterious	4,13	23,8	0,48	0,55	neutral	0,35	neutral	0,43	neutral	0,33	neutral	0,46	1	neutral	0,64	neutral	0,44	NA	0	deleterious	0,72	medium_impact	-0,66	medium_impact	0,05	medium_impact	1,5	0,46	0,8	15,42	14,21	N	0,43	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14045	14045	A	T	MI.22885	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1709	570	Q	L	cAa/cTa	0,63	0	0	possibly_damaging	0,72	neutral	0,71	neutral	1,06	neutral	0,45	deleterious	-4,72	low_impact	1,61	neutral	0,78	neutral	0,68	deleterious	3,95	23,6	0,34	0,5	neutral	0,43	neutral	0,44	neutral	0,22	neutral	0,48	0	neutral	0,67	deleterious	0,5	neutral	-3	deleterious	0,72	low_impact	-1,14	medium_impact	0,45	medium_impact	0,27	0,27	0,8	15,42	14,21	N	0,26	N	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14045	14045	A	G	MI.22886	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1709	570	Q	R	cAa/cGa	0,63	0	0	possibly_damaging	0,66	neutral	0,35	neutral	0,86	neutral	-2,28	neutral	-2,28	medium_impact	2,96	neutral	0,75	neutral	0,52	deleterious	3,62	23,2	0,59	0,65	neutral	0,43	neutral	0,46	neutral	0,38	neutral	0,49	0	neutral	0,71	neutral	0,35	NA	0	deleterious	0,73	low_impact	-1,02	medium_impact	0,08	medium_impact	1,5	0,49	0,8	15,42	14,21	N	0,46	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14045	14045	A	C	MI.22887	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1709	570	Q	P	cAa/cCa	0,63	0	0	possibly_damaging	0,9	neutral	0,25	neutral	0,84	deleterious	-3,25	deleterious	-3,96	medium_impact	2,96	neutral	0,74	neutral	0,3	deleterious	3,46	23	0,18	0,45	disease	0,62	disease	0,72	disease	0,64	disease	0,72	4	neutral	0,93	neutral	0,18	NA	0	deleterious	0,82	low_impact	-1,65	medium_impact	-0,03	medium_impact	1,5	0,52	0,8	15,42	14,21	N	0,3	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14046	14046	A	T	MI.22888	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1710	570	Q	H	caA/caT	0,86	0	0	benign	0,02	neutral	0,54	neutral	0,87	neutral	-2,05	neutral	-1,5	neutral_impact	0,57	neutral	0,86	neutral	0,96	deleterious	2,41	18,9	0,56	0,6	disease	0,64	neutral	0,35	neutral	0,32	disease	0,62	2	neutral	0,43	deleterious	0,76	neutral	-6	deleterious	0,76	medium_impact	0,86	medium_impact	0,27	medium_impact	-0,68	0,58	0,8	15,42	14,21	N	0,31	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14046	14046	A	C	MI.22889	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1710	570	Q	H	caA/caC	0,86	0	0	benign	0,02	neutral	0,54	neutral	0,87	neutral	-2,05	neutral	-1,5	neutral_impact	0,57	neutral	0,86	neutral	0,96	deleterious	2,24	17,79	0,56	0,6	disease	0,64	neutral	0,35	neutral	0,32	disease	0,62	2	neutral	0,43	deleterious	0,76	neutral	-6	deleterious	0,76	medium_impact	0,86	medium_impact	0,27	medium_impact	-0,68	0,58	0,8	15,42	14,21	N	0,31	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6097	6097	T	A	MI.2289	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	194	65	M	K	aTa/aAa	7,07	1	0	probably_damaging	0,98	deleterious	0	neutral	2,37	deleterious	-4,69	deleterious	-3,83	high_impact	5,17	damaging	0,54	damaging	0,07	deleterious	3,93	23,5	0,15	0,55	neutral	0,32	disease	0,93	disease	0,78	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,35	low_impact	-1,48	high_impact	3,68	0,33	0,9	3,12	7,58	P	0,66	P	0,93	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14047	14047	A	C	MI.22890	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1711	571	I	L	Atc/Ctc	-1,21	0	0	benign	0,08	neutral	0,76	neutral	1,09	neutral	0,9	neutral	0,35	neutral_impact	0,18	neutral	0,79	neutral	0,98	neutral	-0,8	0,04	0,56	0,6	neutral	0,25	neutral	0,06	neutral	0,19	neutral	0,26	5	neutral	0,14	deleterious	0,84	neutral	-6	neutral	0,19	medium_impact	0,26	medium_impact	0,51	low_impact	-1,04	0,39	0,8	30,18	19,78	N	0,43	N	0,27	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14047	14047	A	G	MI.22891	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1711	571	I	V	Atc/Gtc	-1,21	0	0	benign	0,01	neutral	0,51	neutral	1,04	neutral	0,4	neutral	-0,15	low_impact	1,75	neutral	0,85	neutral	0,94	neutral	-0,49	0,23	0,6	0,65	neutral	0,38	neutral	0,08	neutral	0,35	neutral	0,31	4	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	1,15	medium_impact	0,24	medium_impact	0,4	0,36	0,8	30,18	19,78	N	0,42	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14047	14047	A	T	MI.22892	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1711	571	I	F	Atc/Ttc	-1,21	0	0	possibly_damaging	0,47	neutral	0,73	neutral	0,93	neutral	-1,53	neutral	-1,28	low_impact	1,4	neutral	0,78	neutral	0,6	deleterious	2,14	17,12	0,6	0,65	neutral	0,41	neutral	0,33	neutral	0,5	neutral	0,48	0	neutral	0,36	deleterious	0,63	neutral	-3	deleterious	0,57	medium_impact	-0,7	medium_impact	0,47	medium_impact	0,08	0,35	0,8	30,18	19,78	N	0,23	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14048	14048	T	C	MI.22893	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1712	571	I	T	aTc/aCc	-7,4	0	0	benign	0,01	neutral	0,43	neutral	1,01	neutral	0,17	neutral	-1,27	neutral_impact	-0,84	neutral	0,88	neutral	0,98	neutral	-0,45	0,29	0,54	0,6	neutral	0,31	neutral	0,14	neutral	0,23	neutral	0,3	4	neutral	0,56	deleterious	0,71	neutral	-6	neutral	0,12	medium_impact	1,15	medium_impact	0,17	low_impact	-1,97	0,24	0,8	30,18	19,78	N	0,4	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14048	14048	T	A	MI.22894	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1712	571	I	N	aTc/aAc	-7,4	0	0	possibly_damaging	0,47	neutral	0,3	neutral	0,92	neutral	-1,95	neutral	-2,42	neutral_impact	0,2	neutral	0,82	neutral	0,68	deleterious	3,23	22,8	0,41	0,5	disease	0,67	neutral	0,4	neutral	0,26	disease	0,62	2	neutral	0,67	neutral	0,42	neutral	-3	deleterious	0,6	medium_impact	-0,7	medium_impact	0,03	low_impact	-1,02	0,43	0,8	30,18	19,78	N	0,31	N	0,46	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14048	14048	T	G	MI.22895	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1712	571	I	S	aTc/aGc	-7,4	0	0	benign	0,03	neutral	0,44	neutral	1,03	neutral	0,34	neutral	-1,58	neutral_impact	-0,04	neutral	0,87	neutral	0,87	neutral	1,09	11,18	0,46	0,55	disease	0,53	neutral	0,38	neutral	0,25	neutral	0,41	2	neutral	0,53	deleterious	0,71	neutral	-6	deleterious	0,43	medium_impact	0,69	medium_impact	0,18	low_impact	-1,24	0,38	0,8	30,18	19,78	N	0,31	N	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14049	14049	C	G	MI.22896	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1713	571	I	M	atC/atG	-2,81	0	0	benign	0,08	neutral	0,27	neutral	1,05	neutral	0,58	neutral	0,71	neutral_impact	0,16	neutral	0,82	neutral	0,99	neutral	1,04	10,9	0,69	0,75	neutral	0,26	neutral	0,09	neutral	0,18	neutral	0,3	4	neutral	0,7	deleterious	0,6	neutral	-6	deleterious	0,54	medium_impact	0,26	medium_impact	-0,01	low_impact	-1,06	0,5	0,8	30,18	19,78	N	0,54	P	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14049	14049	C	A	MI.22897	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1713	571	I	M	atC/atA	-2,81	0	0	benign	0,08	neutral	0,27	neutral	1,05	neutral	0,58	neutral	0,71	neutral_impact	0,16	neutral	0,82	neutral	0,99	neutral	1,44	13,02	0,69	0,75	neutral	0,26	neutral	0,09	neutral	0,18	neutral	0,3	4	neutral	0,7	deleterious	0,6	neutral	-6	deleterious	0,54	medium_impact	0,26	medium_impact	-0,01	low_impact	-1,06	0,5	0,8	30,18	19,78	N	0,54	P	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14050	14050	T	A	MI.22898	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1714	572	S	T	Tcc/Acc	-5,79	0	0	benign	0,04	neutral	0,48	neutral	1,02	neutral	0,19	neutral	0,15	neutral_impact	-0,26	neutral	0,91	neutral	0,98	neutral	1,78	14,87	0,44	0,55	neutral	0,37	neutral	0,05	neutral	0,37	neutral	0,25	5	neutral	0,48	deleterious	0,72	neutral	-6	deleterious	0,63	medium_impact	0,57	medium_impact	0,21	low_impact	-1,44	0,58	0,8	29,52	23,23	N	0,44	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14050	14050	T	G	MI.22899	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1714	572	S	A	Tcc/Gcc	-5,79	0	0	possibly_damaging	0,45	neutral	0,59	neutral	0,97	neutral	-0,36	neutral	-0,55	neutral_impact	0,26	neutral	0,84	neutral	0,92	neutral	1,55	13,6	0,52	0,6	neutral	0,38	neutral	0,03	neutral	0,23	neutral	0,22	6	neutral	0,41	deleterious	0,57	neutral	-3	deleterious	0,63	medium_impact	-0,66	medium_impact	0,32	medium_impact	-0,97	0,52	0,8	29,52	23,23	N	0,37	N	0,21	polymorphism	1	0,01	rs879112261	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8633	8633	A	T	MI.229	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	107	36	Y	F	tAt/tTt	2,9	0,2	0	benign	0,14	neutral	0,71	neutral	4,39	neutral	-0,32	neutral	-1,44	neutral_impact	0,02	neutral	0,87	neutral	0,54	neutral	1,28	12,15	0,55	0,65	disease	0,8	neutral	0,39	neutral	0,35	disease	0,66	3	neutral	0,17	deleterious	0,79	neutral	-6	neutral	0,29	medium_impact	-0,01	medium_impact	0,51	low_impact	-1,08	0,39	0,9	29,2	23,72	N	0,26	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6098	6098	A	C	MI.2290	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	195	65	M	I	atA/atC	7,53	1	0	probably_damaging	0,96	deleterious	0	neutral	2,51	neutral	-1,69	deleterious	-2,55	high_impact	4,08	damaging	0,52	damaging	0,11	deleterious	3,24	22,8	0,35	0,55	disease	0,78	disease	0,91	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,85	low_impact	-2,06	low_impact	-1,48	high_impact	2,67	0,52	0,9	3,12	7,58	P	0,56	P	0,87	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14050	14050	T	C	MI.22900	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1714	572	S	P	Tcc/Ccc	-5,79	0	0	possibly_damaging	0,86	neutral	0,22	neutral	0,93	neutral	-1,09	neutral	-1,7	neutral_impact	0,04	neutral	0,75	neutral	0,84	deleterious	2,33	18,39	0,4	0,5	disease	0,52	neutral	0,15	neutral	0,38	neutral	0,25	5	neutral	0,91	neutral	0,18	neutral	-3	deleterious	0,7	low_impact	-1,5	medium_impact	-0,07	low_impact	-1,17	0,55	0,8	29,52	23,23	N	0,4	N	0,63	polymorphism	1	0,03	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	14051	14051	C	T	MI.22901	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1715	572	S	F	tCc/tTc	-0,52	0	0	possibly_damaging	0,84	neutral	0,77	neutral	0,89	neutral	-2,11	neutral	-1,37	low_impact	0,92	neutral	0,8	neutral	0,75	deleterious	2,19	17,42	0,32	0,5	disease	0,6	neutral	0,24	neutral	0,33	disease	0,53	1	neutral	0,81	neutral	0,47	neutral	-3	deleterious	0,7	low_impact	-1,43	medium_impact	0,52	medium_impact	-0,36	0,32	0,8	29,52	23,23	N	0,23	N	0,81	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14051	14051	C	G	MI.22902	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1715	572	S	C	tCc/tGc	-0,52	0	0	probably_damaging	0,97	neutral	0,18	neutral	0,87	deleterious	-4,23	neutral	-1,59	low_impact	1,9	neutral	0,73	neutral	0,42	deleterious	2,42	18,98	0,37	0,5	disease	0,83	neutral	0,22	neutral	0,31	disease	0,51	0	neutral	0,98	neutral	0,11	neutral	-2	deleterious	0,71	low_impact	-2,18	medium_impact	-0,13	medium_impact	0,53	0,56	0,8	29,52	23,23	N	0,37	N	0,55	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14051	14051	C	A	MI.22903	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1715	572	S	Y	tCc/tAc	-0,52	0	0	probably_damaging	0,95	neutral	1	neutral	0,88	neutral	-2,53	neutral	-1,36	low_impact	1,54	neutral	0,82	neutral	0,78	neutral	1,52	13,42	0,32	0,5	neutral	0,44	neutral	0,23	neutral	0,44	neutral	0,42	2	neutral	0,95	deleterious	0,53	neutral	-2	deleterious	0,67	low_impact	-1,96	high_impact	1,89	medium_impact	0,2	0,56	0,8	29,52	23,23	N	0,23	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14053	14053	A	T	MI.22904	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1717	573	T	S	Acc/Tcc	-5,33	0	0,02	benign	0,02	neutral	0,43	neutral	1	neutral	0,05	neutral	0,41	neutral_impact	-0,38	neutral	0,84	neutral	1	neutral	-0,18	1,23	0,43	0,55	neutral	0,29	neutral	0,09	neutral	0,24	neutral	0,28	4	neutral	0,55	deleterious	0,71	neutral	-6	neutral	0,12	medium_impact	0,86	medium_impact	0,17	low_impact	-1,55	0,38	0,8	23,71	13,29	N	0,46	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14053	14053	A	G	MI.22905	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1717	573	T	A	Acc/Gcc	-5,33	0	0,02	benign	0,01	neutral	0,53	neutral	1,1	neutral	1,16	neutral	1,83	neutral_impact	0,28	neutral	0,88	neutral	1	neutral	-0,55	0,17	0,57	0,65	neutral	0,28	neutral	0,05	neutral	0,23	neutral	0,23	5	neutral	0,46	deleterious	0,76	neutral	-6	neutral	0,09	medium_impact	1,15	medium_impact	0,26	medium_impact	-0,95	0,31	0,8	23,71	13,29	N	0,31	N	0	polymorphism	1	0,01	rs200134839	.	.	.	.	prostate tumor	.	.	.	.	.	.	.	.	.
chrM	14053	14053	A	C	MI.22906	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1717	573	T	P	Acc/Ccc	-5,33	0	0,02	benign	0,41	neutral	0,21	neutral	0,97	neutral	-0,74	neutral	-1,41	medium_impact	1,98	neutral	0,74	neutral	0,76	neutral	1,06	10,99	0,22	0,45	disease	0,79	neutral	0,44	disease	0,71	disease	0,67	3	neutral	0,76	neutral	0,4	neutral	-3	neutral	0,29	medium_impact	-0,6	medium_impact	-0,09	medium_impact	0,61	0,31	0,8	23,71	13,29	N	0,37	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14054	14054	C	T	MI.22907	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1718	573	T	I	aCc/aTc	-2,81	0	0	benign	0,01	neutral	0,41	neutral	1,01	neutral	0,11	neutral	-0,95	neutral_impact	-0,57	neutral	0,76	neutral	0,84	deleterious	0,5	7,42	0,31	0,45	disease	0,51	neutral	0,1	neutral	0,22	neutral	0,24	5	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,14	medium_impact	1,15	medium_impact	0,15	low_impact	-1,72	0,48	0,8	23,71	13,29	N	0,38	N	0,16	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14054	14054	C	G	MI.22908	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1718	573	T	S	aCc/aGc	-2,81	0	0	benign	0,02	neutral	0,43	neutral	1	neutral	0,05	neutral	0,41	neutral_impact	-0,38	neutral	0,84	neutral	1	neutral	-0,47	0,26	0,43	0,55	neutral	0,29	neutral	0,09	neutral	0,24	neutral	0,28	4	neutral	0,55	deleterious	0,71	neutral	-6	neutral	0,12	medium_impact	0,86	medium_impact	0,17	low_impact	-1,55	0,38	0,8	23,71	13,29	N	0,43	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14054	14054	C	A	MI.22909	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1718	573	T	N	aCc/aAc	-2,81	0	0	benign	0,26	neutral	0,32	neutral	0,99	neutral	-0,16	neutral	-1,65	medium_impact	1,98	neutral	0,79	neutral	0,68	deleterious	0,75	9,14	0,47	0,55	disease	0,71	neutral	0,25	neutral	0,48	disease	0,57	1	neutral	0,61	deleterious	0,53	neutral	-3	neutral	0,21	medium_impact	-0,32	medium_impact	0,05	medium_impact	0,61	0,43	0,8	23,71	13,29	N	0,34	N	0,17	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6098	6098	A	T	MI.2291	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	195	65	M	I	atA/atT	7,53	1	0	probably_damaging	0,96	deleterious	0	neutral	2,51	neutral	-1,69	deleterious	-2,55	high_impact	4,08	damaging	0,52	damaging	0,11	deleterious	3,3	22,8	0,35	0,55	disease	0,78	disease	0,91	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,85	low_impact	-2,06	low_impact	-1,48	high_impact	2,67	0,52	0,9	3,12	7,58	P	0,56	P	0,87	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14056	14056	T	G	MI.22910	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1720	574	S	A	Tcc/Gcc	-9,46	0	0	benign	0,08	neutral	0,59	neutral	0,64	neutral	-2,13	neutral	-1,85	low_impact	1,57	neutral	0,88	neutral	0,96	deleterious	0,5	7,46	0,58	0,65	neutral	0,47	neutral	0,13	neutral	0,44	neutral	0,3	4	neutral	0,33	deleterious	0,76	neutral	-6	neutral	0,16	medium_impact	0,26	medium_impact	0,32	medium_impact	0,23	0,7	0,85	5,97	9,72	N	0,4	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14056	14056	T	C	MI.22911	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1720	574	S	P	Tcc/Ccc	-9,46	0	0	probably_damaging	0,94	neutral	0,21	neutral	0,53	deleterious	-4,83	deleterious	-3,99	medium_impact	2,47	neutral	0,73	neutral	0,6	deleterious	2,9	21,8	0,31	0,45	disease	0,76	disease	0,55	disease	0,64	disease	0,55	1	neutral	0,96	neutral	0,14	deleterious	1	deleterious	0,75	low_impact	-1,88	medium_impact	-0,09	medium_impact	1,05	0,66	0,8	5,97	9,72	N	0,31	N	0,97	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14056	14056	T	A	MI.22912	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1720	574	S	T	Tcc/Acc	-9,46	0	0	possibly_damaging	0,74	neutral	0,49	neutral	0,62	neutral	-2,38	neutral	-2,28	neutral_impact	0,61	neutral	0,86	neutral	0,85	neutral	1,25	11,98	0,39	0,5	neutral	0,47	neutral	0,21	neutral	0,28	neutral	0,38	3	neutral	0,72	neutral	0,38	neutral	-3	deleterious	0,49	low_impact	-1,18	medium_impact	0,22	medium_impact	-0,65	0,65	0,8	5,97	9,72	N	0,32	N	0,28	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14057	14057	C	G	MI.22913	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1721	574	S	C	tCc/tGc	-0,52	0	0	probably_damaging	0,98	neutral	0,17	neutral	0,53	deleterious	-5,33	deleterious	-3,86	medium_impact	2,82	neutral	0,71	neutral	0,39	deleterious	3,68	23,3	0,33	0,5	disease	0,91	disease	0,54	disease	0,58	disease	0,75	5	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,75	low_impact	-2,35	medium_impact	-0,15	medium_impact	1,37	0,55	0,8	5,97	9,72	N	0,32	N	0,51	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14057	14057	C	A	MI.22914	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1721	574	S	Y	tCc/tAc	-0,52	0	0	probably_damaging	0,98	neutral	1	neutral	0,55	deleterious	-3,81	deleterious	-4,81	medium_impact	2,01	neutral	0,82	neutral	0,38	deleterious	4,19	23,8	0,28	0,45	disease	0,82	disease	0,57	neutral	0,45	disease	0,55	1	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,78	low_impact	-2,35	high_impact	1,89	medium_impact	0,63	0,66	0,8	5,97	9,72	N	0,19	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14057	14057	C	T	MI.22915	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1721	574	S	F	tCc/tTc	-0,52	0	0	probably_damaging	0,97	neutral	0,74	neutral	0,56	deleterious	-3,7	deleterious	-4,78	medium_impact	2,82	neutral	0,75	neutral	0,43	deleterious	4,36	24,1	0,3	0,45	disease	0,86	disease	0,59	disease	0,62	disease	0,72	4	neutral	0,96	neutral	0,39	deleterious	1	deleterious	0,77	low_impact	-2,18	medium_impact	0,48	medium_impact	1,37	0,34	0,8	5,97	9,72	N	0,21	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14059	14059	A	C	MI.22916	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1723	575	I	L	Atc/Ctc	-6,25	0	0	benign	0,08	neutral	1	neutral	1	neutral	-0,08	neutral	-0,26	neutral_impact	-0,18	neutral	0,81	neutral	0,83	deleterious	0,3	5,69	0,59	0,65	neutral	0,44	neutral	0,12	neutral	0,21	neutral	0,33	3	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,27	medium_impact	0,26	high_impact	1,89	low_impact	-1,37	0,49	0,8	22,06	12,92	N	0,28	N	0,24	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14059	14059	A	G	MI.22917	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1723	575	I	V	Atc/Gtc	-6,25	0	0	benign	0,02	neutral	0,6	neutral	1,01	neutral	0,31	neutral	0,17	neutral_impact	0,74	neutral	0,92	neutral	0,94	deleterious	-0,02	2,39	0,63	0,7	neutral	0,33	neutral	0,12	neutral	0,42	neutral	0,33	3	neutral	0,37	deleterious	0,79	neutral	-6	neutral	0,11	medium_impact	0,86	medium_impact	0,33	medium_impact	-0,53	0,39	0,8	22,06	12,92	N	0,29	N	0,36	polymorphism	1	0	rs878865648	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14059	14059	A	T	MI.22918	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1723	575	I	F	Atc/Ttc	-6,25	0	0	possibly_damaging	0,59	neutral	0,71	neutral	0,97	neutral	-1,84	neutral	-1,43	neutral_impact	0,57	neutral	0,8	neutral	0,66	deleterious	2,45	19,13	0,54	0,6	neutral	0,43	neutral	0,37	neutral	0,41	neutral	0,46	1	neutral	0,51	deleterious	0,56	neutral	-3	deleterious	0,61	medium_impact	-0,9	medium_impact	0,45	medium_impact	-0,68	0,59	0,8	22,06	12,92	N	0,22	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14060	14060	T	C	MI.22919	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1724	575	I	T	aTc/aCc	1,08	0	0	benign	0,02	neutral	0,81	neutral	1,13	neutral	1,94	neutral	1,07	neutral_impact	-0,94	neutral	0,9	neutral	0,99	neutral	-1,07	0,01	0,44	0,55	neutral	0,28	neutral	0,07	neutral	0,19	neutral	0,28	4	neutral	0,15	deleterious	0,9	neutral	-6	neutral	0,12	medium_impact	0,86	medium_impact	0,58	low_impact	-2,06	0,37	0,8	22,06	12,92	N	0,39	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6099	6099	A	T	MI.2292	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	196	66	I	F	Atc/Ttc	2,21	1	0	possibly_damaging	0,57	deleterious	0	neutral	2,35	deleterious	-5,33	neutral	-2,47	high_impact	5,08	neutral	0,62	damaging	0,05	deleterious	3,63	23,2	0,26	0,55	disease	0,73	disease	0,78	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,22	deleterious	5	deleterious	0,68	medium_impact	-0,87	low_impact	-1,48	high_impact	3,59	0,79	0,9	2,53	6,64	P	0,61	P	0,85	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14060	14060	T	G	MI.22920	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1724	575	I	S	aTc/aGc	1,08	0	0	benign	0,27	neutral	0,86	neutral	1,12	neutral	1,88	neutral	-0,18	neutral_impact	-0,36	neutral	0,83	neutral	0,98	neutral	1,03	10,83	0,43	0,55	neutral	0,36	neutral	0,35	neutral	0,28	neutral	0,46	1	neutral	0,15	deleterious	0,8	neutral	-6	deleterious	0,46	medium_impact	-0,34	medium_impact	0,67	low_impact	-1,53	0,49	0,8	22,06	12,92	N	0,32	N	0,39	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14060	14060	T	A	MI.22921	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1724	575	I	N	aTc/aAc	1,08	0	0	possibly_damaging	0,59	neutral	0,59	neutral	1,05	neutral	0,97	neutral	-0,99	neutral_impact	0,65	neutral	0,82	neutral	0,75	deleterious	3,14	22,6	0,4	0,5	disease	0,5	neutral	0,38	neutral	0,44	neutral	0,14	7	neutral	0,53	deleterious	0,5	neutral	-3	deleterious	0,61	medium_impact	-0,9	medium_impact	0,32	medium_impact	-0,61	0,61	0,8	22,06	12,92	N	0,26	N	0,46	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14061	14061	C	A	MI.22922	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1725	575	I	M	atC/atA	-3,04	0	0	benign	0,05	neutral	0,36	neutral	0,97	neutral	-1,44	neutral	-0,01	neutral_impact	0	neutral	0,86	neutral	0,99	deleterious	2,38	18,69	0,64	0,7	disease	0,66	neutral	0,13	neutral	0,22	neutral	0,42	2	neutral	0,61	deleterious	0,66	neutral	-6	deleterious	0,63	medium_impact	0,47	medium_impact	0,1	low_impact	-1,2	0,72	0,85	22,06	12,92	N	0,44	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14061	14061	C	G	MI.22923	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1725	575	I	M	atC/atG	-3,04	0	0	benign	0,05	neutral	0,36	neutral	0,97	neutral	-1,44	neutral	-0,01	neutral_impact	0	neutral	0,86	neutral	0,99	deleterious	1,86	15,32	0,64	0,7	disease	0,66	neutral	0,13	neutral	0,22	neutral	0,42	2	neutral	0,61	deleterious	0,66	neutral	-6	deleterious	0,63	medium_impact	0,47	medium_impact	0,1	low_impact	-1,2	0,72	0,85	22,06	12,92	N	0,44	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14062	14062	A	T	MI.22924	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1726	576	I	F	Atc/Ttc	-7,4	0	0	benign	0,41	neutral	0,71	neutral	0,92	neutral	-0,82	neutral	-0,6	medium_impact	2,4	neutral	0,81	neutral	0,78	neutral	0,97	10,52	0,55	0,6	neutral	0,49	neutral	0,38	neutral	0,5	neutral	0,42	2	neutral	0,31	deleterious	0,65	neutral	-3	deleterious	0,47	medium_impact	-0,6	medium_impact	0,45	medium_impact	0,99	0,56	0,8	23,05	14,51	N	0,26	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14062	14062	A	G	MI.22925	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1726	576	I	V	Atc/Gtc	-7,4	0	0	benign	0,01	neutral	0,52	neutral	0,93	neutral	-0,74	neutral	0,03	low_impact	1,6	neutral	0,87	neutral	0,97	neutral	-0,2	1,08	0,67	0,7	neutral	0,3	neutral	0,1	neutral	0,32	neutral	0,32	4	neutral	0,47	deleterious	0,76	neutral	-6	neutral	0,13	medium_impact	1,15	medium_impact	0,25	medium_impact	0,26	0,56	0,8	23,05	14,51	N	0,42	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14062	14062	A	C	MI.22926	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1726	576	I	L	Atc/Ctc	-7,4	0	0	benign	0,03	neutral	0,68	neutral	1,02	neutral	0,15	neutral	0,3	neutral_impact	0,74	neutral	0,8	neutral	0,97	deleterious	0,02	2,8	0,48	0,55	neutral	0,21	neutral	0,14	neutral	0,28	neutral	0,28	4	neutral	0,27	deleterious	0,83	neutral	-6	neutral	0,13	medium_impact	0,69	medium_impact	0,41	medium_impact	-0,53	0,54	0,8	23,05	14,51	N	0,37	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14063	14063	T	G	MI.22927	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1727	576	I	S	aTc/aGc	-4,42	0	0,01	benign	0,11	neutral	0,47	neutral	0,93	neutral	-0,73	neutral	0,06	low_impact	1,92	neutral	0,82	neutral	0,93	neutral	1,22	11,85	0,45	0,55	neutral	0,45	neutral	0,38	neutral	0,41	neutral	0,46	1	neutral	0,45	deleterious	0,68	neutral	-6	neutral	0,23	medium_impact	0,12	medium_impact	0,2	medium_impact	0,55	0,58	0,8	23,05	14,51	N	0,37	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14063	14063	T	A	MI.22928	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1727	576	I	N	aTc/aAc	-4,42	0	0,01	benign	0,01	neutral	0,34	neutral	0,85	neutral	-2,34	neutral	-0,52	medium_impact	2,4	neutral	0,83	neutral	0,72	neutral	1,53	13,47	0,39	0,5	disease	0,77	neutral	0,47	disease	0,53	disease	0,65	3	neutral	0,65	deleterious	0,67	neutral	-3	deleterious	0,45	medium_impact	1,15	medium_impact	0,07	medium_impact	0,99	0,68	0,85	23,05	14,51	N	0,35	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14063	14063	T	C	MI.22929	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1727	576	I	T	aTc/aCc	-4,42	0	0,01	benign	0	neutral	0,44	neutral	0,95	neutral	-0,51	neutral	0,77	neutral_impact	0,56	neutral	0,92	neutral	0,99	neutral	-1,01	0,02	0,5	0,6	neutral	0,4	neutral	0,12	neutral	0,28	neutral	0,28	5	neutral	0,56	deleterious	0,72	neutral	-6	neutral	0,13	high_impact	2,1	medium_impact	0,18	medium_impact	-0,69	0,51	0,8	23,05	14,51	N	0,42	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	T14063C	Potentially functional variant cosegregating with LHON 3635A	+	-	Reported	1
chrM	6099	6099	A	G	MI.2293	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	196	66	I	V	Atc/Gtc	2,21	1	0	benign	0,03	deleterious	0	neutral	2,65	neutral	-1,25	neutral	-0,61	medium_impact	3,39	neutral	0,63	damaging	0,08	deleterious	2,94	22	0,42	0,55	neutral	0,22	neutral	0,43	neutral	0,39	neutral	0,39	2	deleterious	1	deleterious	0,49	deleterious	1	neutral	0,16	medium_impact	0,66	low_impact	-1,48	high_impact	2,03	0,64	0,9	2,53	6,64	P	0,53	P	0,23	disease_causing	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14064	14064	C	G	MI.22930	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1728	576	I	M	atC/atG	-2,58	0	0,01	possibly_damaging	0,61	neutral	0,24	neutral	0,9	neutral	-1,17	neutral	0,41	low_impact	1,68	neutral	0,83	neutral	0,98	neutral	1,46	13,12	0,67	0,7	neutral	0,43	neutral	0,15	neutral	0,31	neutral	0,32	4	neutral	0,77	neutral	0,32	neutral	-3	deleterious	0,51	medium_impact	-0,93	medium_impact	-0,04	medium_impact	0,33	0,74	0,85	23,05	14,51	N	0,46	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14064	14064	C	A	MI.22931	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1728	576	I	M	atC/atA	-2,58	0	0,01	possibly_damaging	0,61	neutral	0,24	neutral	0,9	neutral	-1,17	neutral	0,41	low_impact	1,68	neutral	0,83	neutral	0,98	deleterious	1,91	15,64	0,67	0,7	neutral	0,43	neutral	0,15	neutral	0,31	neutral	0,32	4	neutral	0,77	neutral	0,32	neutral	-3	deleterious	0,51	medium_impact	-0,93	medium_impact	-0,04	medium_impact	0,33	0,74	0,85	23,05	14,51	N	0,46	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14065	14065	A	G	MI.22932	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1729	577	T	A	Acc/Gcc	-8,31	0	0	benign	0,02	neutral	0,76	neutral	0,99	neutral	-0,17	neutral	-1,8	medium_impact	2,67	neutral	0,79	neutral	0,75	deleterious	0,71	8,89	0,76	0,8	neutral	0,35	neutral	0,35	neutral	0,46	neutral	0,47	1	neutral	0,2	deleterious	0,87	neutral	-3	neutral	0,22	medium_impact	0,86	medium_impact	0,51	medium_impact	1,24	0,5	0,8	14,76	11,3	N	0,27	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14065	14065	A	C	MI.22933	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1729	577	T	P	Acc/Ccc	-8,31	0	0	possibly_damaging	0,73	neutral	0,3	neutral	0,9	neutral	-2,84	deleterious	-3,18	medium_impact	2,47	neutral	0,61	neutral	0,37	deleterious	3,36	22,9	0,16	0,45	disease	0,55	disease	0,8	disease	0,7	disease	0,74	5	neutral	0,79	neutral	0,29	NA	0	deleterious	0,7	low_impact	-1,16	medium_impact	0,03	medium_impact	1,05	0,63	0,8	14,76	11,3	N	0,26	N	0,72	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14065	14065	A	T	MI.22934	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1729	577	T	S	Acc/Tcc	-8,31	0	0	benign	0,03	neutral	0,8	neutral	1,02	neutral	0,25	neutral	-1,59	neutral_impact	-0,1	neutral	0,85	neutral	0,92	deleterious	0,13	3,89	0,56	0,6	neutral	0,27	neutral	0,18	neutral	0,2	neutral	0,26	5	neutral	0,14	deleterious	0,89	neutral	-6	neutral	0,42	medium_impact	0,69	medium_impact	0,57	low_impact	-1,29	0,57	0,8	14,76	11,3	N	0,34	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14066	14066	C	G	MI.22935	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1730	577	T	S	aCc/aGc	-2,35	0	0	benign	0,03	neutral	0,8	neutral	1,02	neutral	0,25	neutral	-1,59	neutral_impact	-0,1	neutral	0,85	neutral	0,92	deleterious	0,35	6,19	0,56	0,6	neutral	0,27	neutral	0,18	neutral	0,2	neutral	0,26	5	neutral	0,14	deleterious	0,89	neutral	-6	neutral	0,42	medium_impact	0,69	medium_impact	0,57	low_impact	-1,29	0,57	0,8	14,76	11,3	N	0,31	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14066	14066	C	A	MI.22936	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1730	577	T	N	aCc/aAc	-2,35	0	0	possibly_damaging	0,51	neutral	0,63	neutral	0,97	neutral	-0,35	deleterious	-2,71	medium_impact	2,12	neutral	0,76	neutral	0,8	deleterious	2,32	18,33	0,57	0,65	neutral	0,42	disease	0,54	neutral	0,29	neutral	0,48	0	neutral	0,43	deleterious	0,56	NA	0	deleterious	0,6	medium_impact	-0,76	medium_impact	0,36	medium_impact	0,73	0,73	0,85	14,76	11,3	N	0,27	N	0,54	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14066	14066	C	T	MI.22937	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1730	577	T	I	aCc/aTc	-2,35	0	0	benign	0,02	neutral	0,32	neutral	1,13	neutral	1,12	neutral	-1,12	medium_impact	2,33	neutral	0,88	neutral	0,98	deleterious	0,7	8,85	0,5	0,6	disease	0,53	disease	0,59	neutral	0,35	neutral	0,49	0	neutral	0,67	deleterious	0,65	neutral	-3	neutral	0,18	medium_impact	0,86	medium_impact	0,05	medium_impact	0,93	0,52	0,8	14,76	11,3	N	0,33	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14068	14068	T	A	MI.22938	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1732	578	S	T	Tca/Aca	-13,81	0	0	benign	0,07	neutral	0,5	neutral	0,94	neutral	-0,54	neutral	-2,12	neutral_impact	0,66	neutral	0,93	neutral	0,99	deleterious	2,56	19,88	0,46	0,55	neutral	0,39	neutral	0,18	neutral	0,28	neutral	0,32	4	neutral	0,44	deleterious	0,72	neutral	-6	deleterious	0,69	medium_impact	0,32	medium_impact	0,23	medium_impact	-0,6	0,7	0,85	6,47	11	N	0,42	N	0,01	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14068	14068	T	G	MI.22939	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1732	578	S	A	Tca/Gca	-13,81	0	0	possibly_damaging	0,62	neutral	0,6	neutral	0,89	neutral	-1,29	neutral	-2,47	low_impact	1,64	neutral	0,87	neutral	0,88	deleterious	3,84	23,4	0,6	0,65	neutral	0,46	neutral	0,3	neutral	0,44	neutral	0,47	1	neutral	0,56	deleterious	0,49	neutral	-3	deleterious	0,71	medium_impact	-0,95	medium_impact	0,33	medium_impact	0,3	0,63	0,8	6,47	11	N	0,32	N	0,37	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6099	6099	A	C	MI.2294	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	196	66	I	L	Atc/Ctc	2,21	1	0	benign	0,07	deleterious	0	neutral	2,53	neutral	-1,98	neutral	-1,19	medium_impact	2,9	neutral	0,67	damaging	0,06	deleterious	3,66	23,2	0,26	0,55	neutral	0,28	disease	0,55	neutral	0,48	neutral	0,45	1	deleterious	1	neutral	0,47	deleterious	1	neutral	0,2	medium_impact	0,3	low_impact	-1,48	medium_impact	1,58	0,67	0,9	2,53	6,64	N	0,46	N	0,61	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14068	14068	T	C	MI.22940	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1732	578	S	P	Tca/Cca	-13,81	0	0	probably_damaging	0,92	neutral	0,23	neutral	0,84	neutral	-2,41	deleterious	-4,15	medium_impact	2,15	neutral	0,65	neutral	0,6	deleterious	4,15	23,8	0,33	0,5	disease	0,74	disease	0,81	disease	0,7	disease	0,66	3	neutral	0,95	neutral	0,16	deleterious	1	deleterious	0,87	low_impact	-1,75	medium_impact	-0,06	medium_impact	0,76	0,64	0,8	6,47	11	N	0,31	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14069	14069	C	T	MI.22941	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1733	578	S	L	tCa/tTa	0,86	0	0	possibly_damaging	0,73	neutral	0,72	neutral	0,89	neutral	-1,32	deleterious	-4,88	low_impact	1,7	neutral	0,84	neutral	0,66	deleterious	4,76	24,7	0,51	0,6	neutral	0,43	disease	0,69	neutral	0,45	disease	0,52	0	neutral	0,67	deleterious	0,5	neutral	-3	deleterious	0,74	low_impact	-1,16	medium_impact	0,46	medium_impact	0,35	0,85	0,9	6,47	11	N	0,21	N	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14069	14069	C	G	MI.22942	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1733	578	S	W	tCa/tGa	0,86	0	0	probably_damaging	0,99	neutral	0,18	neutral	0,81	deleterious	-5,43	deleterious	-5,84	medium_impact	2,85	neutral	0,76	neutral	0,44	deleterious	4,5	24,3	0,24	0,45	disease	0,7	disease	0,83	disease	0,57	disease	0,77	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,82	low_impact	-2,64	medium_impact	-0,13	medium_impact	1,4	0,55	0,8	6,47	11	N	0,32	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14071	14071	A	T	MI.22943	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1735	579	T	S	Acc/Tcc	-7,17	0	0	benign	0,09	neutral	0,4	neutral	1,03	neutral	0,33	neutral	0,25	neutral_impact	0,52	neutral	0,88	neutral	0,99	deleterious	0,09	3,51	0,58	0,65	neutral	0,34	neutral	0,26	neutral	0,25	neutral	0,44	1	neutral	0,55	deleterious	0,66	neutral	-6	neutral	0,16	medium_impact	0,21	medium_impact	0,14	medium_impact	-0,73	0,49	0,8	19,57	14,79	N	0,43	N	0,33	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14071	14071	A	G	MI.22944	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1735	579	T	A	Acc/Gcc	-7,17	0	0	benign	0,05	neutral	0,51	neutral	1,03	neutral	0,36	neutral	-2,07	neutral_impact	0,36	neutral	0,77	neutral	0,89	deleterious	0,42	6,82	0,63	0,7	neutral	0,32	neutral	0,18	neutral	0,26	neutral	0,28	5	neutral	0,44	deleterious	0,73	neutral	-6	neutral	0,42	medium_impact	0,47	medium_impact	0,24	medium_impact	-0,87	0,42	0,8	19,57	14,79	N	0,35	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14071	14071	A	C	MI.22945	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1735	579	T	P	Acc/Ccc	-7,17	0	0	probably_damaging	0,91	neutral	0,22	neutral	0,92	neutral	-2,06	neutral	-2,34	low_impact	1,87	neutral	0,74	neutral	0,76	deleterious	2,59	20,1	0,25	0,45	disease	0,59	disease	0,73	neutral	0,44	disease	0,58	2	neutral	0,94	neutral	0,16	neutral	-2	deleterious	0,74	low_impact	-1,7	medium_impact	-0,07	medium_impact	0,51	0,48	0,8	19,57	14,79	N	0,3	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14072	14072	C	G	MI.22946	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1736	579	T	S	aCc/aGc	-0,06	0	0	benign	0,09	neutral	0,4	neutral	1,03	neutral	0,33	neutral	0,25	neutral_impact	0,52	neutral	0,88	neutral	0,99	neutral	-0,24	0,91	0,58	0,65	neutral	0,34	neutral	0,26	neutral	0,25	neutral	0,44	1	neutral	0,55	deleterious	0,66	neutral	-6	neutral	0,16	medium_impact	0,21	medium_impact	0,14	medium_impact	-0,73	0,49	0,8	19,57	14,79	N	0,41	N	0,33	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14072	14072	C	A	MI.22947	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1736	579	T	N	aCc/aAc	-0,06	0	0	possibly_damaging	0,76	neutral	0,32	neutral	1,06	neutral	0,65	neutral	3,34	low_impact	1,24	neutral	0,8	neutral	0,99	deleterious	0,88	9,93	0,57	0,65	neutral	0,33	neutral	0,3	neutral	0,25	neutral	0,45	1	neutral	0,8	neutral	0,28	neutral	-3	deleterious	0,52	low_impact	-1,22	medium_impact	0,05	medium_impact	-0,07	0,67	0,85	19,57	14,79	N	0,37	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14072	14072	C	T	MI.22948	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1736	579	T	I	aCc/aTc	-0,06	0	0	probably_damaging	0,91	neutral	0,4	neutral	0,98	neutral	-0,25	deleterious	-3,07	low_impact	1,09	neutral	0,79	neutral	0,83	deleterious	2,39	18,76	0,41	0,5	neutral	0,32	neutral	0,43	neutral	0,28	neutral	0,45	1	neutral	0,91	neutral	0,25	neutral	-2	deleterious	0,62	low_impact	-1,7	medium_impact	0,14	medium_impact	-0,21	0,4	0,8	19,57	14,79	N	0,3	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14074	14074	C	G	MI.22949	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1738	580	Q	E	Caa/Gaa	-9,69	0	0	probably_damaging	1	neutral	1	neutral	0,63	neutral	-2,32	deleterious	-2,59	high_impact	3,71	neutral	0,66	damaging	0,16	deleterious	3,25	22,8	0,58	0,65	neutral	0,44	disease	0,82	disease	0,79	disease	0,76	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,81	low_impact	-3,6	high_impact	1,89	high_impact	2,19	0,42	0,8	NA	NA	N	0,3	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6100	6100	T	G	MI.2295	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	197	66	I	S	aTc/aGc	8,69	1	0	benign	0,28	deleterious	0	neutral	2,35	deleterious	-5,39	deleterious	-3,72	high_impact	5,08	neutral	0,64	damaging	0,09	deleterious	4,13	23,8	0,2	0,55	disease	0,84	disease	0,78	disease	0,59	disease	0,73	5	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,56	medium_impact	-0,37	low_impact	-1,48	high_impact	3,59	0,53	0,9	2,53	6,64	P	0,61	P	0,62	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14074	14074	C	A	MI.22950	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1738	580	Q	K	Caa/Aaa	-9,69	0	0	probably_damaging	1	neutral	0,94	neutral	0,62	neutral	-2,48	deleterious	-3,47	medium_impact	3,37	damaging	0,59	damaging	0,13	deleterious	4,16	23,8	0,42	0,55	disease	0,53	disease	0,88	disease	0,8	disease	0,82	6	deleterious	1	deleterious	0,47	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,89	medium_impact	1,88	0,38	0,8	NA	NA	N	0,3	N	0,96	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14075	14075	A	C	MI.22951	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1739	580	Q	P	cAa/cCa	4,98	1	0	probably_damaging	1	neutral	0,29	neutral	0,54	deleterious	-4,57	deleterious	-5,18	medium_impact	3,37	neutral	0,62	damaging	0,16	deleterious	3,44	23	0,21	0,45	disease	0,81	disease	0,91	disease	0,82	disease	0,87	7	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,9	low_impact	-3,6	medium_impact	0,02	medium_impact	1,88	0,39	0,8	NA	NA	N	0,49	N	0,95	disease_causing	0,69	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14075	14075	A	G	MI.22952	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1739	580	Q	R	cAa/cGa	4,98	1	0	probably_damaging	1	neutral	0,54	neutral	0,59	neutral	-2,97	deleterious	-3,46	medium_impact	2,74	neutral	0,7	damaging	0,15	deleterious	3,63	23,2	0,6	0,65	disease	0,6	disease	0,89	disease	0,79	disease	0,83	7	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,27	medium_impact	1,3	0,32	0,8	NA	NA	N	0,42	N	0,85	polymorphism	0,89	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14075	14075	A	T	MI.22953	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1739	580	Q	L	cAa/cTa	4,98	1	0	probably_damaging	1	neutral	0,42	neutral	0,58	deleterious	-3,16	deleterious	-6,1	medium_impact	2,91	neutral	0,68	damaging	0,21	deleterious	4	23,6	0,35	0,5	disease	0,74	disease	0,9	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,87	low_impact	-3,6	medium_impact	0,16	medium_impact	1,46	0,17	0,8	NA	NA	N	0,42	N	0,96	disease_causing	0,64	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14076	14076	A	C	MI.22954	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1740	580	Q	H	caA/caC	3,38	1	0	probably_damaging	1	neutral	0,17	neutral	0,62	neutral	-2,54	deleterious	-4,17	medium_impact	1,97	neutral	0,79	neutral	0,48	deleterious	3,45	23	0,61	0,65	disease	0,6	disease	0,58	disease	0,64	neutral	0,49	0	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	-0,15	medium_impact	0,6	0,5	0,8	NA	NA	N	0,38	N	0,94	polymorphism	0,76	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14076	14076	A	T	MI.22955	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1740	580	Q	H	caA/caT	3,38	1	0	probably_damaging	1	neutral	0,17	neutral	0,62	neutral	-2,54	deleterious	-4,17	medium_impact	1,97	neutral	0,79	neutral	0,48	deleterious	3,65	23,2	0,61	0,65	disease	0,6	disease	0,58	disease	0,64	neutral	0,49	0	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	-0,15	medium_impact	0,6	0,5	0,8	NA	NA	N	0,39	N	0,94	polymorphism	0,76	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14077	14077	A	G	MI.22956	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1741	581	K	E	Aaa/Gaa	1,31	0,98	0	probably_damaging	1	neutral	1	neutral	0,9	neutral	-0,96	deleterious	-2,79	medium_impact	3,3	neutral	0,83	damaging	0,24	deleterious	3,9	23,5	0,52	0,6	neutral	0,42	disease	0,79	disease	0,65	disease	0,76	5	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,77	low_impact	-3,6	high_impact	1,89	medium_impact	1,81	0,78	0,85	NA	NA	N	0,31	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14077	14077	A	C	MI.22957	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1741	581	K	Q	Aaa/Caa	1,31	0,98	0	probably_damaging	1	neutral	0,62	neutral	0,92	neutral	-0,77	deleterious	-2,71	low_impact	1,62	neutral	0,82	neutral	0,79	neutral	1,57	13,7	0,6	0,65	neutral	0,45	neutral	0,28	neutral	0,27	neutral	0,46	1	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,35	medium_impact	0,28	0,75	0,85	NA	NA	N	0,36	N	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14078	14078	A	C	MI.22958	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1742	581	K	T	aAa/aCa	2,23	0,96	0	probably_damaging	1	neutral	0,64	neutral	0,92	neutral	-0,69	deleterious	-3,33	low_impact	1,21	neutral	0,83	neutral	0,73	deleterious	2,52	19,59	0,42	0,5	neutral	0,29	neutral	0,34	neutral	0,37	neutral	0,44	1	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	0,37	medium_impact	-0,1	0,6	0,8	NA	NA	N	0,32	N	0,71	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14078	14078	A	T	MI.22959	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1742	581	K	M	aAa/aTa	2,23	0,96	0	probably_damaging	1	neutral	0,13	neutral	0,84	neutral	-2,21	deleterious	-3,95	medium_impact	2,61	neutral	0,83	neutral	0,31	deleterious	3,84	23,4	0,33	0,5	disease	0,7	disease	0,6	disease	0,54	disease	0,68	4	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,22	medium_impact	1,18	0,41	0,8	NA	NA	N	0,41	N	0,8	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6100	6100	T	C	MI.2296	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	197	66	I	T	aTc/aCc	8,69	1	0	benign	0,02	deleterious	0	neutral	2,4	deleterious	-3,62	deleterious	-3,11	high_impact	4,53	neutral	0,62	damaging	0,08	deleterious	3,35	22,9	0,36	0,55	disease	0,74	disease	0,67	disease	0,59	disease	0,67	3	deleterious	1	deleterious	0,49	deleterious	2	neutral	0,3	medium_impact	0,83	low_impact	-1,48	high_impact	3,08	0,73	0,9	2,53	6,64	P	0,52	P	0,76	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14079	14079	A	T	MI.22960	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1743	581	K	N	aaA/aaT	1,08	0,45	0	probably_damaging	1	neutral	0,53	neutral	0,92	neutral	-0,75	deleterious	-3,36	medium_impact	2,06	neutral	0,75	neutral	0,34	deleterious	4,14	23,8	0,66	0,7	neutral	0,35	disease	0,61	neutral	0,42	neutral	0,49	0	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,26	medium_impact	0,68	0,83	0,9	NA	NA	N	0,22	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14079	14079	A	C	MI.22961	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1743	581	K	N	aaA/aaC	1,08	0,45	0	probably_damaging	1	neutral	0,53	neutral	0,92	neutral	-0,75	deleterious	-3,36	medium_impact	2,06	neutral	0,75	neutral	0,34	deleterious	3,96	23,6	0,66	0,7	neutral	0,35	disease	0,61	neutral	0,42	neutral	0,49	0	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,72	low_impact	-3,6	medium_impact	0,26	medium_impact	0,68	0,83	0,9	NA	NA	N	0,22	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14080	14080	G	T	MI.22962	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1744	582	G	C	Ggc/Tgc	-0,29	0,08	0	probably_damaging	1	neutral	0,18	neutral	0,65	deleterious	-5,75	deleterious	-7,9	high_impact	3,78	neutral	0,63	damaging	0,24	deleterious	4,28	24	0,29	0,45	disease	0,95	disease	0,89	disease	0,74	disease	0,84	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,6	medium_impact	-0,13	high_impact	2,25	0,35	0,8	20,07	7,26	N	0,38	N	0,97	disease_causing	0,91	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14080	14080	G	C	MI.22963	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1744	582	G	R	Ggc/Cgc	-0,29	0,08	0	probably_damaging	1	neutral	0,35	neutral	0,69	neutral	-2,93	deleterious	-7,02	medium_impact	3,43	neutral	0,62	damaging	0,23	deleterious	4,11	23,7	0,28	0,45	disease	0,83	disease	0,9	disease	0,76	disease	0,84	7	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,91	low_impact	-3,6	medium_impact	0,08	medium_impact	1,93	0,68	0,85	20,07	7,26	N	0,38	N	1	disease_causing	0,83	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14080	14080	G	A	MI.22964	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1744	582	G	S	Ggc/Agc	-0,29	0,08	0	possibly_damaging	0,78	neutral	0,4	neutral	0,78	neutral	-1,42	deleterious	-5,23	medium_impact	2,58	neutral	0,7	neutral	0,42	deleterious	4,41	24,1	0,29	0,45	disease	0,67	disease	0,79	disease	0,67	disease	0,56	1	neutral	0,78	neutral	0,31	NA	0	deleterious	0,85	low_impact	-1,27	medium_impact	0,14	medium_impact	1,15	0,56	0,8	20,07	7,26	N	0,3	N	1	disease_causing	0,7	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14081	14081	G	A	MI.22965	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1745	582	G	D	gGc/gAc	2,92	1	0	probably_damaging	0,99	neutral	0,21	neutral	0,7	neutral	-2,81	deleterious	-6,14	high_impact	3,78	neutral	0,65	damaging	0,26	deleterious	4,02	23,6	0,23	0,45	disease	0,79	disease	0,89	disease	0,78	disease	0,84	7	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-2,64	medium_impact	-0,09	high_impact	2,25	0,37	0,8	20,07	7,26	P	0,48	N	0,95	disease_causing	0,91	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14081	14081	G	T	MI.22966	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1745	582	G	V	gGc/gTc	2,92	1	0	probably_damaging	0,99	neutral	0,5	neutral	0,67	deleterious	-3,53	deleterious	-7,9	high_impact	3,78	neutral	0,63	neutral	0,28	deleterious	3,93	23,5	0,28	0,45	disease	0,85	disease	0,88	disease	0,72	disease	0,81	6	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,9	low_impact	-2,64	medium_impact	0,23	high_impact	2,25	0,34	0,8	20,07	7,26	N	0,43	N	0,98	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14081	14081	G	C	MI.22967	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1745	582	G	A	gGc/gCc	2,92	1	0	probably_damaging	0,95	neutral	0,51	neutral	0,73	neutral	-2,18	deleterious	-5,25	medium_impact	2,58	neutral	0,67	neutral	0,59	deleterious	3,27	22,8	0,34	0,5	disease	0,69	disease	0,61	disease	0,67	disease	0,52	0	neutral	0,94	neutral	0,28	deleterious	1	deleterious	0,83	low_impact	-1,96	medium_impact	0,24	medium_impact	1,15	0,53	0,8	20,07	7,26	N	0,36	N	0,79	disease_causing	0,74	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14083	14083	A	G	MI.22968	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1747	583	M	V	Ata/Gta	-14,5	0	0	benign	0,26	neutral	0,51	neutral	1,02	neutral	0,49	neutral	-1,38	low_impact	1,38	neutral	0,77	neutral	0,75	neutral	1,02	10,75	0,67	0,7	neutral	0,41	disease	0,72	disease	0,53	disease	0,56	1	neutral	0,39	deleterious	0,63	neutral	-6	neutral	0,25	medium_impact	-0,32	medium_impact	0,24	medium_impact	0,06	0,65	0,8	15,75	12,27	N	0,24	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14083	14083	A	T	MI.22969	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1747	583	M	L	Ata/Tta	-14,5	0	0	benign	0,01	neutral	0,68	neutral	1,23	neutral	2,38	neutral	0,83	neutral_impact	-0,84	neutral	0,81	neutral	0,98	neutral	-1,06	0,01	0,62	0,65	neutral	0,21	neutral	0,29	neutral	0,44	neutral	0,44	1	neutral	0,29	deleterious	0,84	neutral	-6	neutral	0,12	medium_impact	1,15	medium_impact	0,41	low_impact	-1,97	0,65	0,8	15,75	12,27	N	0,31	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6100	6100	T	A	MI.2297	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	197	66	I	N	aTc/aAc	8,69	1	0	possibly_damaging	0,53	deleterious	0	neutral	2,34	deleterious	-6,62	deleterious	-4,36	high_impact	5,08	neutral	0,61	damaging	0,07	deleterious	4,5	24,3	0,22	0,55	disease	0,91	disease	0,71	disease	0,61	disease	0,76	5	deleterious	1	neutral	0,24	deleterious	5	deleterious	0,67	medium_impact	-0,81	low_impact	-1,48	high_impact	3,59	0,65	0,9	2,53	6,64	P	0,62	P	0,94	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14083	14083	A	C	MI.22970	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1747	583	M	L	Ata/Cta	-14,5	0	0	benign	0,01	neutral	0,68	neutral	1,23	neutral	2,38	neutral	0,83	neutral_impact	-0,84	neutral	0,81	neutral	0,98	neutral	-1,17	0,01	0,62	0,65	neutral	0,21	neutral	0,29	neutral	0,44	neutral	0,44	1	neutral	0,29	deleterious	0,84	neutral	-6	neutral	0,12	medium_impact	1,15	medium_impact	0,41	low_impact	-1,97	0,65	0,8	15,75	12,27	N	0,31	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14084	14084	T	C	MI.22971	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1748	583	M	T	aTa/aCa	-3,73	0	0	possibly_damaging	0,64	neutral	0,43	neutral	1,02	neutral	0,49	deleterious	-2,98	low_impact	1,27	neutral	0,77	neutral	0,76	neutral	1,41	12,86	0,52	0,6	neutral	0,42	disease	0,68	disease	0,66	disease	0,55	1	neutral	0,65	neutral	0,4	neutral	-3	deleterious	0,44	medium_impact	-0,98	medium_impact	0,17	medium_impact	-0,04	0,23	0,8	15,75	12,27	N	0,26	N	0,69	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14084	14084	T	A	MI.22972	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1748	583	M	K	aTa/aAa	-3,73	0	0	possibly_damaging	0,71	neutral	0,3	neutral	1	neutral	0,11	deleterious	-3,67	low_impact	1,03	neutral	0,76	neutral	0,69	deleterious	2,5	19,47	0,3	0,45	neutral	0,25	disease	0,87	disease	0,73	disease	0,77	5	neutral	0,78	neutral	0,3	neutral	-3	deleterious	0,53	low_impact	-1,12	medium_impact	0,03	medium_impact	-0,26	0,61	0,8	15,75	12,27	N	0,28	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14085	14085	A	C	MI.22973	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1749	583	M	I	atA/atC	0,4	0	0	benign	0,25	neutral	0,41	neutral	1	neutral	-0,04	neutral	-0,71	low_impact	1,58	neutral	0,75	neutral	0,75	neutral	1,65	14,13	0,59	0,65	neutral	0,41	disease	0,71	disease	0,52	disease	0,54	1	neutral	0,5	deleterious	0,58	neutral	-6	neutral	0,27	medium_impact	-0,29	medium_impact	0,15	medium_impact	0,24	0,56	0,8	15,75	12,27	N	0,34	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14085	14085	A	T	MI.22974	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1749	583	M	I	atA/atT	0,4	0	0	benign	0,25	neutral	0,41	neutral	1	neutral	-0,04	neutral	-0,71	low_impact	1,58	neutral	0,75	neutral	0,75	neutral	1,71	14,45	0,59	0,65	neutral	0,41	disease	0,71	disease	0,52	disease	0,54	1	neutral	0,5	deleterious	0,58	neutral	-6	neutral	0,27	medium_impact	-0,29	medium_impact	0,15	medium_impact	0,24	0,56	0,8	15,75	12,27	N	0,34	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14086	14086	A	T	MI.22975	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1750	584	I	F	Att/Ttt	-0,29	0	0	probably_damaging	0,97	neutral	0,73	neutral	0,68	neutral	-2,55	deleterious	-3,34	medium_impact	2,88	neutral	0,62	neutral	0,36	deleterious	3,88	23,5	0,47	0,55	neutral	0,48	disease	0,88	disease	0,64	disease	0,74	5	neutral	0,97	neutral	0,38	deleterious	1	deleterious	0,8	low_impact	-2,18	medium_impact	0,47	medium_impact	1,43	0,58	0,8	NA	NA	N	0,22	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14086	14086	A	C	MI.22976	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1750	584	I	L	Att/Ctt	-0,29	0	0	possibly_damaging	0,61	neutral	0,91	neutral	0,93	neutral	0,25	neutral	-1,48	medium_impact	2,37	neutral	0,74	neutral	0,83	deleterious	2,83	21,5	0,42	0,55	neutral	0,36	disease	0,74	neutral	0,44	disease	0,53	1	neutral	0,56	deleterious	0,65	NA	0	deleterious	0,72	medium_impact	-0,93	medium_impact	0,79	medium_impact	0,96	0,51	0,8	NA	NA	N	0,28	N	0,67	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14086	14086	A	G	MI.22977	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1750	584	I	V	Att/Gtt	-0,29	0	0	benign	0,18	neutral	0,53	neutral	0,73	neutral	-0,23	neutral	-0,69	medium_impact	2,02	neutral	0,83	neutral	0,96	deleterious	2,02	16,36	0,59	0,65	neutral	0,31	neutral	0,41	neutral	0,49	neutral	0,4	2	neutral	0,36	deleterious	0,68	neutral	-3	deleterious	0,67	medium_impact	-0,12	medium_impact	0,26	medium_impact	0,64	0,41	0,8	NA	NA	N	0,33	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14087	14087	T	A	MI.22978	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1751	584	I	N	aTt/aAt	0,86	0,19	0	probably_damaging	0,98	neutral	0,34	neutral	0,6	deleterious	-4,68	deleterious	-5,87	medium_impact	3,23	neutral	0,62	neutral	0,41	deleterious	4,65	24,5	0,41	0,5	disease	0,83	disease	0,9	disease	0,7	disease	0,78	6	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,86	low_impact	-2,35	medium_impact	0,07	medium_impact	1,75	0,53	0,8	NA	NA	N	0,31	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14087	14087	T	C	MI.22979	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1751	584	I	T	aTt/aCt	0,86	0,19	0	probably_damaging	0,91	neutral	0,56	neutral	0,63	deleterious	-3,02	deleterious	-4,05	medium_impact	3,02	neutral	0,64	neutral	0,52	deleterious	3,59	23,2	0,5	0,6	disease	0,51	disease	0,77	disease	0,67	disease	0,66	3	neutral	0,9	neutral	0,33	deleterious	1	deleterious	0,8	low_impact	-1,7	medium_impact	0,29	medium_impact	1,56	0,48	0,8	NA	NA	N	0,24	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6101	6101	C	A	MI.2298	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	198	66	I	M	atC/atA	5,91	1	0	possibly_damaging	0,75	deleterious	0	neutral	2,4	deleterious	-3,69	neutral	-1,7	high_impact	3,83	neutral	0,66	damaging	0,07	deleterious	3,66	23,2	0,33	0,55	neutral	0,45	disease	0,57	disease	0,52	neutral	0,49	0	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,63	low_impact	-1,21	low_impact	-1,48	high_impact	2,44	0,8	0,9	2,53	6,64	N	0,5	N	0,76	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14087	14087	T	G	MI.22980	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1751	584	I	S	aTt/aGt	0,86	0,19	0	probably_damaging	0,96	neutral	0,55	neutral	0,62	deleterious	-3,65	deleterious	-4,98	medium_impact	3,23	neutral	0,63	neutral	0,48	deleterious	4,41	24,1	0,36	0,5	disease	0,6	disease	0,88	disease	0,69	disease	0,76	5	neutral	0,95	neutral	0,3	deleterious	1	deleterious	0,84	low_impact	-2,06	medium_impact	0,28	medium_impact	1,75	0,46	0,8	NA	NA	N	0,26	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14088	14088	T	A	MI.22981	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1752	584	I	M	atT/atA	5,67	0,88	0	probably_damaging	0,97	neutral	0,23	neutral	0,69	neutral	-2,39	neutral	-2,19	low_impact	1,3	neutral	0,77	neutral	0,96	deleterious	2,74	21	0,62	0,65	disease	0,7	disease	0,65	neutral	0,46	disease	0,52	0	neutral	0,98	neutral	0,13	neutral	-2	deleterious	0,77	low_impact	-2,18	medium_impact	-0,06	medium_impact	-0,02	0,59	0,8	NA	NA	N	0,42	N	0,77	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14088	14088	T	G	MI.22982	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1752	584	I	M	atT/atG	5,67	0,88	0	probably_damaging	0,97	neutral	0,23	neutral	0,69	neutral	-2,39	neutral	-2,19	low_impact	1,3	neutral	0,77	neutral	0,96	deleterious	2,49	19,41	0,62	0,65	disease	0,7	disease	0,65	neutral	0,46	disease	0,52	0	neutral	0,98	neutral	0,13	neutral	-2	deleterious	0,77	low_impact	-2,18	medium_impact	-0,06	medium_impact	-0,02	0,59	0,8	NA	NA	N	0,41	N	0,77	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14089	14089	A	C	MI.22983	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1753	585	K	Q	Aaa/Caa	-6,02	0	0	probably_damaging	1	neutral	0,68	neutral	0,25	deleterious	-4,03	deleterious	-3,55	medium_impact	3,34	damaging	0,53	damaging	0,12	deleterious	3,56	23,1	0,41	0,5	neutral	0,33	disease	0,79	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,41	medium_impact	1,85	0,64	0,8	28,03	7,12	N	0,25	N	0,82	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14089	14089	A	G	MI.22984	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1753	585	K	E	Aaa/Gaa	-6,02	0	0	probably_damaging	1	neutral	1	neutral	0,27	deleterious	-3,63	deleterious	-3,55	high_impact	3,88	damaging	0,59	damaging	0,12	deleterious	4,16	23,8	0,38	0,5	neutral	0,46	disease	0,84	disease	0,77	disease	0,79	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,81	low_impact	-3,6	high_impact	1,89	high_impact	2,34	0,79	0,85	28,03	7,12	N	0,3	N	0,84	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14090	14090	A	C	MI.22985	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1754	585	K	T	aAa/aCa	6,59	1	0	probably_damaging	1	neutral	0,77	neutral	0,26	deleterious	-3,94	deleterious	-5,32	high_impact	3,54	damaging	0,52	damaging	0,11	deleterious	3,77	23,4	0,23	0,45	disease	0,54	disease	0,81	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,82	low_impact	-3,6	medium_impact	0,52	high_impact	2,03	0,49	0,8	28,03	7,12	N	0,45	N	0,75	disease_causing	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14090	14090	A	T	MI.22986	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1754	585	K	M	aAa/aTa	6,59	1	0	probably_damaging	1	neutral	0,25	neutral	0,24	deleterious	-4,5	deleterious	-5,32	medium_impact	3,34	damaging	0,58	damaging	0,08	deleterious	4,08	23,7	0,28	0,45	disease	0,81	disease	0,82	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	-0,03	medium_impact	1,85	0,45	0,8	28,03	7,12	N	0,48	N	0,4	disease_causing	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14091	14091	A	C	MI.22987	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1755	585	K	N	aaA/aaC	6,59	1	0,01	probably_damaging	1	neutral	0,64	neutral	0,25	deleterious	-4,05	deleterious	-4,43	medium_impact	3,19	damaging	0,49	damaging	0,12	deleterious	3,96	23,6	0,52	0,6	disease	0,58	disease	0,82	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,37	medium_impact	1,71	0,73	0,85	28,03	7,12	P	0,55	P	0,63	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14091	14091	A	T	MI.22988	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1755	585	K	N	aaA/aaT	6,59	1	0,01	probably_damaging	1	neutral	0,64	neutral	0,25	deleterious	-4,05	deleterious	-4,43	medium_impact	3,19	damaging	0,49	damaging	0,12	deleterious	4,01	23,6	0,52	0,6	disease	0,58	disease	0,82	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,37	medium_impact	1,71	0,73	0,85	28,03	7,12	P	0,57	P	0,63	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	A14091T	Developmental delay,seizure,hearing loss,diabetes	-	+	Reported	1
chrM	14092	14092	C	A	MI.22989	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1756	586	L	I	Ctt/Att	0,86	0,25	0	probably_damaging	1	neutral	0,37	neutral	1,11	neutral	0,7	neutral	-1,43	neutral_impact	0,64	neutral	0,82	neutral	0,48	deleterious	3,19	22,7	0,38	0,5	neutral	0,48	neutral	0,36	neutral	0,3	neutral	0,43	1	deleterious	1	neutral	0,19	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,11	medium_impact	-0,62	0,8	0,85	18,24	14,19	N	0,26	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6101	6101	C	G	MI.2299	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	198	66	I	M	atC/atG	5,91	1	0	possibly_damaging	0,75	deleterious	0	neutral	2,4	deleterious	-3,69	neutral	-1,7	high_impact	3,83	neutral	0,66	damaging	0,07	deleterious	3,25	22,8	0,33	0,55	neutral	0,45	disease	0,57	disease	0,52	neutral	0,49	0	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,63	low_impact	-1,21	low_impact	-1,48	high_impact	2,44	0,8	0,9	2,53	6,64	N	0,49	N	0,76	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14092	14092	C	G	MI.22990	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1756	586	L	V	Ctt/Gtt	0,86	0,25	0	probably_damaging	1	neutral	0,5	neutral	0,96	neutral	-0,4	neutral	-2,29	low_impact	1,4	neutral	0,82	neutral	0,43	deleterious	2,37	18,63	0,48	0,55	neutral	0,37	neutral	0,4	neutral	0,34	neutral	0,46	1	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,23	medium_impact	0,08	0,68	0,85	18,24	14,19	N	0,25	N	0,35	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14092	14092	C	T	MI.22991	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1756	586	L	F	Ctt/Ttt	0,86	0,25	0	probably_damaging	1	neutral	0,41	neutral	0,85	neutral	-2,23	deleterious	-2,77	low_impact	1,88	neutral	0,8	neutral	0,77	deleterious	2,95	22,1	0,39	0,5	disease	0,54	disease	0,55	neutral	0,37	disease	0,51	0	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,15	medium_impact	0,51	0,7	0,85	18,24	14,19	N	0,26	N	0,84	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14093	14093	T	C	MI.22992	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1757	586	L	P	cTt/cCt	-2,12	0	0	probably_damaging	1	neutral	0,34	neutral	0,84	deleterious	-3,03	deleterious	-5,81	low_impact	1,63	neutral	0,77	neutral	0,41	deleterious	4,01	23,6	0,17	0,45	disease	0,78	disease	0,84	disease	0,67	disease	0,79	6	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,88	low_impact	-3,6	medium_impact	0,07	medium_impact	0,29	0,49	0,8	18,24	14,19	N	0,23	N	0,9	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14093	14093	T	A	MI.22993	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1757	586	L	H	cTt/cAt	-2,12	0	0	probably_damaging	1	neutral	0,39	neutral	0,83	deleterious	-3,29	deleterious	-5,65	medium_impact	2,08	neutral	0,68	damaging	0,19	deleterious	4,46	24,2	0,27	0,45	disease	0,65	disease	0,63	neutral	0,46	disease	0,51	0	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,13	medium_impact	0,7	0,65	0,8	18,24	14,19	N	0,25	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14093	14093	T	G	MI.22994	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1757	586	L	R	cTt/cGt	-2,12	0	0	probably_damaging	1	neutral	0,63	neutral	0,86	neutral	-1,92	deleterious	-5	medium_impact	2,44	neutral	0,65	damaging	0,14	deleterious	4,3	24	0,28	0,45	disease	0,66	disease	0,87	disease	0,66	disease	0,81	6	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,36	medium_impact	1,03	0,7	0,85	18,24	14,19	N	0,18	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14095	14095	T	G	MI.22995	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1759	587	Y	D	Tac/Gac	-20	0	0	probably_damaging	1	neutral	0,2	neutral	0,23	deleterious	-5,72	deleterious	-8,86	high_impact	3,8	neutral	0,66	damaging	0,16	deleterious	4,03	23,6	0,31	0,5	disease	0,85	disease	0,88	disease	0,82	disease	0,88	8	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,1	high_impact	2,27	0,46	0,8	NA	NA	N	0,39	N	0,96	polymorphism	0,96	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14095	14095	T	C	MI.22996	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1759	587	Y	H	Tac/Cac	-20	0	0	probably_damaging	1	neutral	0,46	neutral	0,28	deleterious	-3,85	deleterious	-4,43	medium_impact	2,48	neutral	0,65	damaging	0,19	deleterious	3,66	23,2	0,45	0,55	disease	0,78	disease	0,81	disease	0,81	disease	0,78	6	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,19	medium_impact	1,06	0,65	0,8	NA	NA	N	0,25	N	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14095	14095	T	A	MI.22997	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1759	587	Y	N	Tac/Aac	-20	0	0	probably_damaging	1	neutral	0,33	neutral	0,24	deleterious	-5,11	deleterious	-7,97	high_impact	3,8	neutral	0,63	damaging	0,15	deleterious	4,1	23,7	0,36	0,5	disease	0,85	disease	0,86	disease	0,76	disease	0,82	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	0,06	high_impact	2,27	0,5	0,8	NA	NA	N	0,36	N	0,99	polymorphism	0,95	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14096	14096	A	C	MI.22998	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1760	587	Y	S	tAc/tCc	4,52	1	0	probably_damaging	1	neutral	0,4	neutral	0,28	deleterious	-4,68	deleterious	-7,97	medium_impact	3,1	neutral	0,66	damaging	0,15	deleterious	3,83	23,4	0,34	0,5	disease	0,72	disease	0,83	disease	0,75	disease	0,79	6	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,14	medium_impact	1,63	0,54	0,8	NA	NA	N	0,4	N	0,97	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14096	14096	A	T	MI.22999	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1760	587	Y	F	tAc/tTc	4,52	1	0	probably_damaging	1	neutral	0,7	neutral	0,33	neutral	-1,88	deleterious	-3,54	medium_impact	2,52	neutral	0,65	damaging	0,24	deleterious	3,5	23,1	0,53	0,6	disease	0,83	disease	0,78	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	0,44	medium_impact	1,1	0,5	0,8	NA	NA	N	0,39	N	0,8	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8536	8536	A	G	MI.23	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	10	4	N	D	Aat/Gat	6,84	1	0	benign	0	neutral	0,38	neutral	4,5	neutral	-0,73	deleterious	-3,21	medium_impact	2,3	neutral	0,86	neutral	0,49	neutral	1,53	13,48	0,77	0,8	disease	0,77	neutral	0,35	neutral	0,36	disease	0,65	3	neutral	0,62	deleterious	0,69	neutral	-3	neutral	0,17	high_impact	2,09	medium_impact	0,17	medium_impact	0,87	0,39	0,9	41,59	7,51	P	0,6	P	0,88	disease_causing	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8635	8635	C	G	MI.230	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	109	37	L	V	Ctc/Gtc	-1,26	0	0	benign	0,39	neutral	0,17	neutral	4,33	neutral	-0,86	neutral	-1,91	low_impact	1,47	neutral	0,87	neutral	0,53	neutral	1,54	13,54	0,49	0,65	disease	0,52	neutral	0,4	disease	0,54	neutral	0,5	0	neutral	0,8	neutral	0,39	neutral	-6	neutral	0,42	medium_impact	-0,57	medium_impact	-0,1	medium_impact	0,16	0,45	0,9	20,35	20,89	N	0,4	N	0,37	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6102	6102	T	C	MI.2300	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	199	67	F	L	Ttc/Ctc	-1,49	0	0	benign	0,13	deleterious	0	neutral	2,42	neutral	-2,22	deleterious	-3,86	medium_impact	3,04	neutral	0,66	damaging	0,15	deleterious	3,95	23,6	0,33	0,55	neutral	0,33	disease	0,78	disease	0,59	disease	0,65	3	deleterious	1	neutral	0,44	deleterious	1	neutral	0,25	medium_impact	0,02	low_impact	-1,48	medium_impact	1,71	0,56	0,9	1,17	6,64	N	0,35	N	0,83	disease_causing	0,55	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14096	14096	A	G	MI.23000	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1760	587	Y	C	tAc/tGc	4,52	1	0	probably_damaging	1	neutral	0,16	neutral	0,23	deleterious	-6,53	deleterious	-7,97	high_impact	3,8	neutral	0,61	damaging	0,14	deleterious	3,66	23,2	0,33	0,5	disease	0,95	disease	0,87	disease	0,8	disease	0,89	8	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,17	high_impact	2,27	0,28	0,8	NA	NA	N	0,48	N	1	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14098	14098	T	C	MI.23001	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1762	588	F	L	Ttc/Ctc	-1,89	0	0	benign	0,17	neutral	0,66	neutral	1,89	neutral	3,27	deleterious	-4,9	neutral_impact	0,03	neutral	0,76	neutral	0,78	deleterious	0,46	7,13	0,31	0,45	neutral	0,19	neutral	0,23	neutral	0,39	neutral	0,41	2	neutral	0,22	deleterious	0,75	neutral	-6	neutral	0,27	medium_impact	-0,09	medium_impact	0,39	low_impact	-1,18	0,79	0,85	5,14	9,29	N	0,37	N	0,86	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14098	14098	T	A	MI.23002	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1762	588	F	I	Ttc/Atc	-1,89	0	0	benign	0,17	neutral	0,4	neutral	1,07	neutral	0,58	deleterious	-4,9	medium_impact	2,14	neutral	0,75	neutral	0,68	deleterious	2,86	21,6	0,16	0,45	neutral	0,44	disease	0,72	disease	0,56	disease	0,67	3	neutral	0,52	deleterious	0,62	neutral	-3	neutral	0,36	medium_impact	-0,09	medium_impact	0,14	medium_impact	0,75	0,7	0,85	5,14	9,29	N	0,34	N	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14098	14098	T	G	MI.23003	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1762	588	F	V	Ttc/Gtc	-1,89	0	0	benign	0,17	neutral	0,5	neutral	0,96	neutral	-0,4	deleterious	-5,72	medium_impact	2,29	neutral	0,73	neutral	0,7	deleterious	2,48	19,35	0,2	0,45	neutral	0,35	disease	0,81	disease	0,57	disease	0,76	5	neutral	0,4	deleterious	0,67	neutral	-3	neutral	0,35	medium_impact	-0,09	medium_impact	0,23	medium_impact	0,89	0,7	0,85	5,14	9,29	N	0,33	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14099	14099	T	C	MI.23004	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1763	588	F	S	tTc/tCc	0,4	0	0	benign	0,17	neutral	0,41	neutral	0,86	deleterious	-3,75	deleterious	-6,15	medium_impact	2,14	neutral	0,85	neutral	0,76	deleterious	2,49	19,42	0,19	0,45	disease	0,57	disease	0,72	disease	0,58	disease	0,69	4	neutral	0,51	deleterious	0,62	neutral	-3	neutral	0,39	medium_impact	-0,09	medium_impact	0,15	medium_impact	0,75	0,59	0,8	5,14	9,29	N	0,32	N	0,53	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14099	14099	T	A	MI.23005	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1763	588	F	Y	tTc/tAc	0,4	0	0	benign	0,17	neutral	1	neutral	0,86	deleterious	-3,71	neutral	-2,45	medium_impact	2,84	neutral	0,68	neutral	0,61	deleterious	2,57	19,92	0,22	0,45	disease	0,55	disease	0,7	disease	0,61	disease	0,73	5	neutral	0,17	deleterious	0,92	neutral	-3	neutral	0,4	medium_impact	-0,09	high_impact	1,89	medium_impact	1,39	0,75	0,85	5,14	9,29	N	0,21	N	0,72	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14099	14099	T	G	MI.23006	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1763	588	F	C	tTc/tGc	0,4	0	0	benign	0,17	neutral	0,18	neutral	0,86	deleterious	-4,47	deleterious	-6,47	medium_impact	2,84	neutral	0,64	neutral	0,57	deleterious	2,41	18,9	0,19	0,45	disease	0,63	disease	0,85	disease	0,64	disease	0,78	6	neutral	0,79	deleterious	0,51	neutral	-3	neutral	0,4	medium_impact	-0,09	medium_impact	-0,13	medium_impact	1,39	0,46	0,8	5,14	9,29	N	0,31	N	0,97	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14100	14100	C	A	MI.23007	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1764	588	F	L	ttC/ttA	1,77	0,01	0	benign	0,17	neutral	0,66	neutral	1,89	neutral	3,27	deleterious	-4,9	neutral_impact	0,03	neutral	0,76	neutral	0,78	neutral	0,99	10,58	0,31	0,45	neutral	0,19	neutral	0,23	neutral	0,39	neutral	0,41	2	neutral	0,22	deleterious	0,75	neutral	-6	neutral	0,27	medium_impact	-0,09	medium_impact	0,39	low_impact	-1,18	0,79	0,85	5,14	9,29	N	0,41	N	0,86	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14100	14100	C	G	MI.23008	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1764	588	F	L	ttC/ttG	1,77	0,01	0	benign	0,17	neutral	0,66	neutral	1,89	neutral	3,27	deleterious	-4,9	neutral_impact	0,03	neutral	0,76	neutral	0,78	deleterious	0,66	8,54	0,31	0,45	neutral	0,19	neutral	0,23	neutral	0,39	neutral	0,41	2	neutral	0,22	deleterious	0,75	neutral	-6	neutral	0,27	medium_impact	-0,09	medium_impact	0,39	low_impact	-1,18	0,79	0,85	5,14	9,29	N	0,4	N	0,86	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14101	14101	C	G	MI.23009	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1765	589	L	V	Ctc/Gtc	-4,87	0	0	possibly_damaging	0,54	neutral	0,49	neutral	0,82	neutral	-1,27	neutral	-2,21	low_impact	1,49	neutral	0,75	neutral	0,73	deleterious	3,13	22,6	0,3	0,45	neutral	0,48	neutral	0,42	neutral	0,39	neutral	0,43	1	neutral	0,53	deleterious	0,48	neutral	-3	deleterious	0,49	medium_impact	-0,81	medium_impact	0,22	medium_impact	0,16	0,75	0,85	3,81	8,29	N	0,31	N	0,49	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6102	6102	T	A	MI.2301	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	199	67	F	I	Ttc/Atc	-1,49	0	0	benign	0,04	deleterious	0	neutral	2,32	deleterious	-3,31	deleterious	-3,86	high_impact	4,22	neutral	0,62	damaging	0,2	deleterious	4,27	23,9	0,19	0,55	neutral	0,44	disease	0,91	disease	0,64	disease	0,74	5	deleterious	1	deleterious	0,48	deleterious	2	neutral	0,27	medium_impact	0,54	low_impact	-1,48	high_impact	2,8	0,58	0,9	1,17	6,64	N	0,41	N	0,88	disease_causing	0,53	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14101	14101	C	A	MI.23010	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1765	589	L	I	Ctc/Atc	-4,87	0	0	possibly_damaging	0,54	neutral	0,4	neutral	0,81	neutral	-1,35	neutral	-1,48	low_impact	1,69	neutral	0,79	neutral	0,79	deleterious	3,77	23,4	0,26	0,45	disease	0,55	neutral	0,4	neutral	0,36	disease	0,6	2	neutral	0,6	neutral	0,43	neutral	-3	deleterious	0,49	medium_impact	-0,81	medium_impact	0,14	medium_impact	0,34	0,77	0,85	3,81	8,29	N	0,32	N	0,56	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14101	14101	C	T	MI.23011	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1765	589	L	F	Ctc/Ttc	-4,87	0	0	possibly_damaging	0,54	neutral	0,71	neutral	0,75	neutral	-2,21	deleterious	-3,12	medium_impact	2,03	neutral	0,79	neutral	0,7	deleterious	3,67	23,3	0,31	0,45	neutral	0,45	disease	0,53	neutral	0,49	neutral	0,49	0	neutral	0,44	deleterious	0,59	NA	0	deleterious	0,49	medium_impact	-0,81	medium_impact	0,45	medium_impact	0,65	0,68	0,85	3,81	8,29	N	0,22	N	0,8	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14102	14102	T	C	MI.23012	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1766	589	L	P	cTc/cCc	-2,35	0	0	possibly_damaging	0,54	neutral	0,2	neutral	0,69	deleterious	-4,4	deleterious	-5,59	medium_impact	2,38	neutral	0,6	neutral	0,52	deleterious	3,59	23,2	0,12	0,4	disease	0,85	disease	0,84	disease	0,65	disease	0,79	6	neutral	0,79	neutral	0,33	NA	0	deleterious	0,65	medium_impact	-0,81	medium_impact	-0,1	medium_impact	0,97	0,62	0,8	3,81	8,29	N	0,26	N	0,95	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14102	14102	T	A	MI.23013	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1766	589	L	H	cTc/cAc	-2,35	0	0	possibly_damaging	0,54	neutral	0,53	neutral	0,69	deleterious	-4,34	deleterious	-5,59	medium_impact	2,73	neutral	0,76	neutral	0,6	deleterious	3,81	23,4	0,12	0,4	disease	0,84	disease	0,67	disease	0,61	disease	0,74	5	neutral	0,51	deleterious	0,5	NA	0	deleterious	0,57	medium_impact	-0,81	medium_impact	0,26	medium_impact	1,29	0,58	0,8	3,81	8,29	N	0,24	N	0,86	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14102	14102	T	G	MI.23014	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1766	589	L	R	cTc/cGc	-2,35	0	0	possibly_damaging	0,54	neutral	0,36	neutral	0,7	deleterious	-3,75	deleterious	-4,75	medium_impact	2,73	neutral	0,71	neutral	0,53	deleterious	3,91	23,5	0,1	0,4	disease	0,79	disease	0,86	disease	0,64	disease	0,78	6	neutral	0,63	neutral	0,41	NA	0	deleterious	0,63	medium_impact	-0,81	medium_impact	0,1	medium_impact	1,29	0,51	0,8	3,81	8,29	N	0,28	N	0,98	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14104	14104	T	C	MI.23015	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1768	590	S	P	Tct/Cct	-3,27	0	0	possibly_damaging	0,54	neutral	0,19	neutral	0,74	deleterious	-4,14	deleterious	-4,28	medium_impact	2,99	neutral	0,61	damaging	0,15	deleterious	3,62	23,2	0,17	0,45	disease	0,77	disease	0,9	disease	0,67	disease	0,78	6	neutral	0,8	neutral	0,33	NA	0	deleterious	0,57	medium_impact	-0,81	medium_impact	-0,12	medium_impact	1,53	0,81	0,85	8,96	7,19	N	0,27	N	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14104	14104	T	G	MI.23016	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1768	590	S	A	Tct/Gct	-3,27	0	0	possibly_damaging	0,54	neutral	0,51	neutral	0,82	neutral	-1,64	deleterious	-2,56	low_impact	1,8	neutral	0,77	neutral	0,42	deleterious	2,12	16,98	0,46	0,55	neutral	0,48	neutral	0,46	neutral	0,49	neutral	0,45	1	neutral	0,52	deleterious	0,49	neutral	-3	neutral	0,43	medium_impact	-0,81	medium_impact	0,24	medium_impact	0,44	0,72	0,85	8,96	7,19	N	0,24	N	0,49	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14104	14104	T	A	MI.23017	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1768	590	S	T	Tct/Act	-3,27	0	0	possibly_damaging	0,54	neutral	0,42	neutral	0,83	neutral	-1,48	neutral	-2,29	neutral_impact	0,53	neutral	0,81	neutral	0,61	deleterious	2,09	16,79	0,31	0,45	neutral	0,38	neutral	0,25	neutral	0,41	neutral	0,44	1	neutral	0,58	neutral	0,44	neutral	-3	neutral	0,4	medium_impact	-0,81	medium_impact	0,16	medium_impact	-0,72	0,81	0,85	8,96	7,19	N	0,29	N	0,71	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14105	14105	C	T	MI.23018	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1769	590	S	F	tCt/tTt	-0,06	0	0	possibly_damaging	0,54	neutral	0,74	neutral	0,82	neutral	-1,61	deleterious	-5,17	medium_impact	2,3	neutral	0,76	damaging	0,24	deleterious	2,78	21,3	0,22	0,45	neutral	0,37	disease	0,82	neutral	0,5	disease	0,69	4	neutral	0,44	deleterious	0,6	NA	0	deleterious	0,44	medium_impact	-0,81	medium_impact	0,48	medium_impact	0,9	0,46	0,8	8,96	7,19	N	0,2	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14105	14105	C	G	MI.23019	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1769	590	S	C	tCt/tGt	-0,06	0	0	possibly_damaging	0,54	neutral	0,17	neutral	0,76	deleterious	-3,09	deleterious	-4,28	medium_impact	2,99	neutral	0,66	damaging	0,19	deleterious	3,28	22,8	0,22	0,45	disease	0,79	disease	0,79	disease	0,53	disease	0,74	5	neutral	0,82	neutral	0,32	NA	0	deleterious	0,48	medium_impact	-0,81	medium_impact	-0,15	medium_impact	1,53	0,72	0,85	8,96	7,19	N	0,3	N	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6102	6102	T	G	MI.2302	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	199	67	F	V	Ttc/Gtc	-1,49	0	0	benign	0,35	deleterious	0	neutral	2,35	neutral	-2,93	deleterious	-4,5	high_impact	5,12	neutral	0,63	damaging	0,15	deleterious	3,95	23,6	0,2	0,55	disease	0,65	disease	0,91	disease	0,67	disease	0,76	5	deleterious	1	neutral	0,33	deleterious	2	neutral	0,36	medium_impact	-0,5	low_impact	-1,48	high_impact	3,63	0,6	0,9	1,17	6,64	P	0,61	P	0,84	disease_causing	0,71	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14105	14105	C	A	MI.23020	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1769	590	S	Y	tCt/tAt	-0,06	0	0	possibly_damaging	0,54	neutral	1	neutral	0,76	deleterious	-3,14	deleterious	-5,17	medium_impact	2,99	neutral	0,75	damaging	0,16	deleterious	3,78	23,4	0,21	0,45	neutral	0,44	disease	0,83	disease	0,63	disease	0,77	5	neutral	0,54	deleterious	0,73	NA	0	deleterious	0,47	medium_impact	-0,81	high_impact	1,89	medium_impact	1,53	0,71	0,85	8,96	7,19	N	0,21	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14107	14107	T	A	MI.23021	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1771	591	F	I	Ttc/Atc	-14,5	0	0	benign	0,17	neutral	0,93	neutral	0,57	neutral	-2,49	deleterious	-5	medium_impact	2,29	neutral	0,75	neutral	0,33	deleterious	2,74	21	0,19	0,45	neutral	0,26	disease	0,81	disease	0,67	disease	0,6	2	neutral	0,08	deleterious	0,88	neutral	-3	neutral	0,35	medium_impact	-0,09	medium_impact	0,85	medium_impact	0,89	0,7	0,85	NA	NA	N	0,28	N	0,95	polymorphism	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14107	14107	T	C	MI.23022	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1771	591	F	L	Ttc/Ctc	-14,5	0	0	benign	0,17	neutral	1	neutral	0,61	neutral	-2,03	deleterious	-4,96	medium_impact	2,27	neutral	0,75	neutral	0,36	deleterious	2,35	18,49	0,42	0,55	neutral	0,36	disease	0,75	disease	0,64	disease	0,58	2	neutral	0,17	deleterious	0,92	neutral	-3	neutral	0,35	medium_impact	-0,09	high_impact	1,89	medium_impact	0,87	0,63	0,8	NA	NA	N	0,25	N	0,92	polymorphism	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14107	14107	T	G	MI.23023	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1771	591	F	V	Ttc/Gtc	-14,5	0	0	benign	0,17	neutral	0,48	neutral	0,59	neutral	-2,25	deleterious	-5,81	medium_impact	3,39	neutral	0,71	damaging	0,18	deleterious	2,43	19,01	0,26	0,45	neutral	0,4	disease	0,86	disease	0,74	disease	0,77	5	neutral	0,43	deleterious	0,66	neutral	-3	neutral	0,38	medium_impact	-0,09	medium_impact	0,21	medium_impact	1,89	0,66	0,8	NA	NA	N	0,33	N	0,95	polymorphism	0,97	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14108	14108	T	A	MI.23024	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1772	591	F	Y	tTc/tAc	5,67	1	0	benign	0,17	neutral	0,7	neutral	0,5	deleterious	-4,03	deleterious	-2,59	medium_impact	3,04	neutral	0,76	damaging	0,27	deleterious	2,54	19,7	0,33	0,5	neutral	0,45	disease	0,75	disease	0,68	disease	0,65	3	neutral	0,18	deleterious	0,77	neutral	-3	neutral	0,38	medium_impact	-0,09	medium_impact	0,44	medium_impact	1,57	0,71	0,85	NA	NA	N	0,48	N	0,88	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14108	14108	T	C	MI.23025	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1772	591	F	S	tTc/tCc	5,67	1	0	benign	0,17	neutral	0,42	neutral	0,58	neutral	-2,46	deleterious	-6,61	medium_impact	2,94	neutral	0,73	damaging	0,2	deleterious	2,51	19,5	0,27	0,45	disease	0,58	disease	0,79	disease	0,67	disease	0,67	3	neutral	0,5	deleterious	0,63	neutral	-3	neutral	0,4	medium_impact	-0,09	medium_impact	0,16	medium_impact	1,48	0,73	0,85	NA	NA	N	0,49	N	0,97	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14108	14108	T	G	MI.23026	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1772	591	F	C	tTc/tGc	5,67	1	0	benign	0,17	neutral	0,12	neutral	0,48	deleterious	-5,11	deleterious	-6,69	high_impact	3,74	neutral	0,67	damaging	0,19	deleterious	2,37	18,63	0,2	0,45	disease	0,76	disease	0,85	disease	0,74	disease	0,79	6	neutral	0,86	deleterious	0,48	neutral	-2	neutral	0,41	medium_impact	-0,09	medium_impact	-0,25	high_impact	2,21	0,59	0,8	NA	NA	N	0,5	N	0,99	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14109	14109	C	G	MI.23027	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1773	591	F	L	ttC/ttG	4,52	1	0	benign	0,17	neutral	1	neutral	0,61	neutral	-2,03	deleterious	-4,96	medium_impact	2,27	neutral	0,75	neutral	0,36	deleterious	2,64	20,5	0,42	0,55	neutral	0,36	disease	0,75	disease	0,64	disease	0,58	2	neutral	0,17	deleterious	0,92	neutral	-3	neutral	0,35	medium_impact	-0,09	high_impact	1,89	medium_impact	0,87	0,63	0,8	NA	NA	N	0,39	N	0,92	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14109	14109	C	A	MI.23028	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1773	591	F	L	ttC/ttA	4,52	1	0	benign	0,17	neutral	1	neutral	0,61	neutral	-2,03	deleterious	-4,96	medium_impact	2,27	neutral	0,75	neutral	0,36	deleterious	2,93	22	0,42	0,55	neutral	0,36	disease	0,75	disease	0,64	disease	0,58	2	neutral	0,17	deleterious	0,92	neutral	-3	neutral	0,35	medium_impact	-0,09	high_impact	1,89	medium_impact	0,87	0,63	0,8	NA	NA	N	0,39	N	0,92	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14110	14110	T	A	MI.23029	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1774	592	F	I	Ttc/Atc	-3,04	0	0,01	benign	0,17	neutral	0,99	neutral	1,11	neutral	1,05	neutral	1,13	neutral_impact	0,02	neutral	0,84	neutral	0,99	neutral	1,34	12,47	0,17	0,45	neutral	0,32	neutral	0,41	neutral	0,44	neutral	0,46	1	neutral	0,14	deleterious	0,91	neutral	-6	neutral	0,29	medium_impact	-0,09	medium_impact	1,33	low_impact	-1,18	0,71	0,85	17,91	17,58	N	0,25	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6103	6103	T	G	MI.2303	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	200	67	F	C	tTc/tGc	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,23	deleterious	-6,85	deleterious	-5,15	high_impact	5,12	neutral	0,67	damaging	0,15	deleterious	3,98	23,6	0,19	0,55	disease	0,94	disease	0,86	disease	0,68	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,35	low_impact	-1,48	high_impact	3,63	0,33	0,9	1,17	6,64	P	0,66	P	0,91	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14110	14110	T	C	MI.23030	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1774	592	F	L	Ttc/Ctc	-3,04	0	0,01	benign	0,17	neutral	1	neutral	1,2	neutral	1,58	neutral	2,62	neutral_impact	-0,53	neutral	0,89	neutral	0,99	neutral	-0,43	0,33	0,32	0,5	neutral	0,18	neutral	0,24	neutral	0,38	neutral	0,43	1	neutral	0,17	deleterious	0,92	neutral	-6	neutral	0,26	medium_impact	-0,09	high_impact	1,89	low_impact	-1,69	0,68	0,85	17,91	17,58	N	0,33	N	0	polymorphism	1	0	rs371451099	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14110	14110	T	G	MI.23031	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1774	592	F	V	Ttc/Gtc	-3,04	0	0,01	benign	0,17	neutral	0,58	neutral	1,11	neutral	1,03	neutral	0,39	low_impact	1,6	neutral	0,89	neutral	0,94	deleterious	2,25	17,82	0,23	0,45	neutral	0,33	disease	0,58	neutral	0,49	neutral	0,48	0	neutral	0,31	deleterious	0,71	neutral	-6	neutral	0,3	medium_impact	-0,09	medium_impact	0,31	medium_impact	0,26	0,75	0,85	17,91	17,58	N	0,27	N	0,14	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14111	14111	T	C	MI.23032	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1775	592	F	S	tTc/tCc	-4,87	0	0	benign	0,17	neutral	0,66	neutral	0,96	neutral	-0,62	neutral	-1,72	low_impact	1,09	neutral	0,77	neutral	0,82	deleterious	2,53	19,63	0,17	0,45	neutral	0,45	disease	0,52	disease	0,63	disease	0,67	3	neutral	0,22	deleterious	0,75	neutral	-6	neutral	0,32	medium_impact	-0,09	medium_impact	0,39	medium_impact	-0,21	0,62	0,8	17,91	17,58	N	0,2	N	0,39	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14111	14111	T	G	MI.23033	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1775	592	F	C	tTc/tGc	-4,87	0	0	benign	0,17	neutral	0,11	neutral	0,91	neutral	-2,56	neutral	-1,22	medium_impact	2,41	neutral	0,72	neutral	0,62	deleterious	2,4	18,84	0,19	0,45	disease	0,73	disease	0,7	disease	0,65	disease	0,73	5	neutral	0,87	deleterious	0,47	neutral	-3	neutral	0,36	medium_impact	-0,09	medium_impact	-0,27	medium_impact	1	0,52	0,8	17,91	17,58	N	0,32	N	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14111	14111	T	A	MI.23034	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1775	592	F	Y	tTc/tAc	-4,87	0	0	benign	0,17	neutral	0,63	neutral	0,92	neutral	-1,74	neutral	-0,95	medium_impact	2,41	neutral	0,81	neutral	0,8	deleterious	2,54	19,72	0,2	0,45	disease	0,55	neutral	0,47	disease	0,63	disease	0,65	3	neutral	0,25	deleterious	0,73	neutral	-3	neutral	0,35	medium_impact	-0,09	medium_impact	0,36	medium_impact	1	0,72	0,85	17,91	17,58	N	0,28	N	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14112	14112	C	A	MI.23035	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1776	592	F	L	ttC/ttA	2,92	0,73	0	benign	0,17	neutral	1	neutral	1,2	neutral	1,58	neutral	2,62	neutral_impact	-0,53	neutral	0,89	neutral	0,99	deleterious	0,25	5,22	0,32	0,5	neutral	0,18	neutral	0,24	neutral	0,38	neutral	0,43	1	neutral	0,17	deleterious	0,92	neutral	-6	neutral	0,26	medium_impact	-0,09	high_impact	1,89	low_impact	-1,69	0,68	0,85	17,91	17,58	N	0,37	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14112	14112	C	G	MI.23036	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1776	592	F	L	ttC/ttG	2,92	0,73	0	benign	0,17	neutral	1	neutral	1,2	neutral	1,58	neutral	2,62	neutral_impact	-0,53	neutral	0,89	neutral	0,99	deleterious	-0,05	2,14	0,32	0,5	neutral	0,18	neutral	0,24	neutral	0,38	neutral	0,43	1	neutral	0,17	deleterious	0,92	neutral	-6	neutral	0,26	medium_impact	-0,09	high_impact	1,89	low_impact	-1,69	0,68	0,85	17,91	17,58	N	0,36	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14113	14113	T	G	MI.23037	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1777	593	F	V	Ttc/Gtc	-6,94	0	0	benign	0,17	neutral	0,52	neutral	1,03	neutral	0,3	neutral	1,94	neutral_impact	0,55	neutral	0,85	neutral	0,99	neutral	0,96	10,45	0,28	0,45	neutral	0,26	neutral	0,48	neutral	0,38	neutral	0,46	1	neutral	0,38	deleterious	0,68	neutral	-6	neutral	0,29	medium_impact	-0,09	medium_impact	0,25	medium_impact	-0,7	0,6	0,8	6,63	9,63	N	0,27	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14113	14113	T	C	MI.23038	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1777	593	F	L	Ttc/Ctc	-6,94	0	0	benign	0,17	neutral	0,76	neutral	1,3	neutral	1,98	neutral	1,65	neutral_impact	-1,44	neutral	0,79	neutral	0,98	deleterious	0,02	2,8	0,44	0,55	neutral	0,18	neutral	0,18	neutral	0,3	neutral	0,24	5	neutral	0,13	deleterious	0,8	neutral	-6	neutral	0,26	medium_impact	-0,09	medium_impact	0,51	low_impact	-2,52	0,73	0,85	6,63	9,63	N	0,27	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14113	14113	T	A	MI.23039	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1777	593	F	I	Ttc/Atc	-6,94	0	0	benign	0,17	neutral	0,54	neutral	1,08	neutral	0,75	neutral	2,36	neutral_impact	-1,86	neutral	0,83	neutral	0,99	neutral	-0,11	1,69	0,22	0,45	neutral	0,21	neutral	0,13	neutral	0,3	neutral	0,22	6	neutral	0,36	deleterious	0,69	neutral	-6	neutral	0,26	medium_impact	-0,09	medium_impact	0,27	low_impact	-2,9	0,57	0,8	6,63	9,63	N	0,28	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6103	6103	T	C	MI.2304	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	200	67	F	S	tTc/tCc	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,24	deleterious	-5,29	deleterious	-5,15	high_impact	4,57	neutral	0,66	damaging	0,21	deleterious	4,1	23,7	0,19	0,55	disease	0,91	disease	0,86	disease	0,65	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	3,12	0,53	0,9	1,17	6,64	P	0,55	P	0,84	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14114	14114	T	G	MI.23040	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1778	593	F	C	tTc/tGc	-2,81	0	0	benign	0,17	neutral	0,17	neutral	0,93	neutral	-1,38	neutral	-0,76	low_impact	1	neutral	0,7	neutral	0,69	deleterious	2,37	18,64	0,2	0,45	neutral	0,42	disease	0,64	disease	0,51	disease	0,57	1	neutral	0,8	deleterious	0,5	neutral	-6	neutral	0,31	medium_impact	-0,09	medium_impact	-0,15	medium_impact	-0,29	0,51	0,8	6,63	9,63	N	0,39	N	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14114	14114	T	C	MI.23041	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1778	593	F	S	tTc/tCc	-2,81	0	0	benign	0,17	neutral	0,49	neutral	0,95	neutral	-0,77	neutral	-1,14	low_impact	0,8	neutral	0,72	neutral	0,81	deleterious	2,56	19,88	0,19	0,45	neutral	0,45	neutral	0,45	disease	0,57	disease	0,52	0	neutral	0,41	deleterious	0,66	neutral	-6	neutral	0,32	medium_impact	-0,09	medium_impact	0,22	medium_impact	-0,47	0,56	0,8	6,63	9,63	N	0,35	N	0,44	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14114	14114	T	A	MI.23042	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1778	593	F	Y	tTc/tAc	-2,81	0	0	benign	0,17	neutral	1	neutral	0,92	neutral	-1,83	neutral	-0,75	low_impact	1	neutral	0,75	neutral	0,85	deleterious	2,58	19,95	0,31	0,45	disease	0,55	neutral	0,43	disease	0,56	disease	0,64	3	neutral	0,17	deleterious	0,92	neutral	-6	neutral	0,34	medium_impact	-0,09	high_impact	1,89	medium_impact	-0,29	0,64	0,8	6,63	9,63	N	0,25	N	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14115	14115	C	G	MI.23043	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1779	593	F	L	ttC/ttG	1,08	0,13	0	benign	0,17	neutral	0,76	neutral	1,3	neutral	1,98	neutral	1,65	neutral_impact	-1,44	neutral	0,79	neutral	0,98	deleterious	0,43	6,9	0,44	0,55	neutral	0,18	neutral	0,18	neutral	0,3	neutral	0,24	5	neutral	0,13	deleterious	0,8	neutral	-6	neutral	0,26	medium_impact	-0,09	medium_impact	0,51	low_impact	-2,52	0,73	0,85	6,63	9,63	N	0,33	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14115	14115	C	A	MI.23044	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1779	593	F	L	ttC/ttA	1,08	0,13	0	benign	0,17	neutral	0,76	neutral	1,3	neutral	1,98	neutral	1,65	neutral_impact	-1,44	neutral	0,79	neutral	0,98	deleterious	0,71	8,91	0,44	0,55	neutral	0,18	neutral	0,18	neutral	0,3	neutral	0,24	5	neutral	0,13	deleterious	0,8	neutral	-6	neutral	0,26	medium_impact	-0,09	medium_impact	0,51	low_impact	-2,52	0,73	0,85	6,63	9,63	N	0,33	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14116	14116	C	A	MI.23045	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1780	594	P	T	Cca/Aca	-6,25	0	0	benign	0,17	neutral	0,66	neutral	1,18	neutral	3,14	neutral	2,22	neutral_impact	-1,53	neutral	0,8	neutral	0,98	neutral	-0,77	0,05	0,35	0,5	neutral	0,17	neutral	0,03	neutral	0,25	neutral	0,21	6	neutral	0,22	deleterious	0,75	neutral	-6	neutral	0,26	medium_impact	-0,09	medium_impact	0,39	low_impact	-2,6	0,72	0,85	25,54	22,05	N	0,33	N	0,14	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14116	14116	C	G	MI.23046	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1780	594	P	A	Cca/Gca	-6,25	0	0	benign	0,17	neutral	0,61	neutral	1,08	neutral	2,1	neutral	0,91	neutral_impact	0,42	neutral	0,79	neutral	0,88	neutral	1,32	12,39	0,3	0,45	neutral	0,27	neutral	0,11	disease	0,52	neutral	0,31	4	neutral	0,28	deleterious	0,72	neutral	-6	neutral	0,29	medium_impact	-0,09	medium_impact	0,34	medium_impact	-0,82	0,64	0,8	25,54	22,05	N	0,35	N	0,36	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14116	14116	C	T	MI.23047	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1780	594	P	S	Cca/Tca	-6,25	0	0	benign	0,17	neutral	0,4	neutral	1,17	neutral	3,06	neutral	2,79	neutral_impact	-1,38	neutral	0,83	neutral	0,98	deleterious	0,32	5,85	0,4	0,5	neutral	0,26	neutral	0,06	neutral	0,28	neutral	0,24	5	neutral	0,52	deleterious	0,62	neutral	-6	neutral	0,27	medium_impact	-0,09	medium_impact	0,14	low_impact	-2,46	0,46	0,8	25,54	22,05	N	0,37	N	0,21	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14117	14117	C	G	MI.23048	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1781	594	P	R	cCa/cGa	0,17	0	0	benign	0,17	neutral	0,32	neutral	1	neutral	0,26	neutral	-0,42	low_impact	1,39	neutral	0,74	neutral	0,63	deleterious	1,85	15,31	0,28	0,45	neutral	0,35	disease	0,61	disease	0,66	disease	0,74	5	neutral	0,62	deleterious	0,58	neutral	-6	neutral	0,33	medium_impact	-0,09	medium_impact	0,05	medium_impact	0,07	0,7	0,85	25,54	22,05	N	0,37	N	0,64	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14117	14117	C	A	MI.23049	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1781	594	P	Q	cCa/cAa	0,17	0	0	benign	0,17	neutral	0,27	neutral	1	neutral	0,18	neutral	0,14	low_impact	1,39	neutral	0,79	neutral	0,7	deleterious	2,34	18,43	0,2	0,45	neutral	0,33	neutral	0,27	disease	0,55	neutral	0,47	1	neutral	0,68	deleterious	0,55	neutral	-6	neutral	0,29	medium_impact	-0,09	medium_impact	-0,01	medium_impact	0,07	0,52	0,8	25,54	22,05	N	0,41	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6103	6103	T	A	MI.2305	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	200	67	F	Y	tTc/tAc	7,53	1	0	possibly_damaging	0,66	deleterious	0	neutral	2,33	deleterious	-3,16	neutral	-1,93	high_impact	4,78	neutral	0,68	damaging	0,15	deleterious	4,11	23,7	0,19	0,55	disease	0,81	disease	0,81	disease	0,61	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	5	deleterious	0,67	low_impact	-1,03	low_impact	-1,48	high_impact	3,32	0,63	0,9	1,17	6,64	P	0,72	P	0,59	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14117	14117	C	T	MI.23050	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1781	594	P	L	cCa/cTa	0,17	0	0	benign	0,17	neutral	0,69	neutral	1,16	neutral	2,98	neutral	-0,69	neutral_impact	0,24	neutral	0,77	neutral	0,77	deleterious	2,66	20,6	0,32	0,5	neutral	0,32	neutral	0,38	disease	0,52	neutral	0,49	0	neutral	0,19	deleterious	0,76	neutral	-6	neutral	0,3	medium_impact	-0,09	medium_impact	0,42	medium_impact	-0,98	0,83	0,85	25,54	22,05	N	0,3	N	0,74	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14119	14119	C	A	MI.23051	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1783	595	L	I	Ctc/Atc	-6,94	0	0	possibly_damaging	0,54	neutral	0,44	neutral	0,94	neutral	-0,35	neutral	-0,34	neutral_impact	0,3	neutral	0,8	neutral	0,97	neutral	1,37	12,62	0,34	0,5	neutral	0,21	neutral	0,06	neutral	0,28	neutral	0,26	5	neutral	0,57	neutral	0,45	neutral	-3	neutral	0,41	medium_impact	-0,81	medium_impact	0,18	medium_impact	-0,93	0,65	0,8	21,89	13,98	N	0,42	N	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14119	14119	C	G	MI.23052	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1783	595	L	V	Ctc/Gtc	-6,94	0	0	possibly_damaging	0,54	neutral	0,27	neutral	0,89	neutral	-0,64	neutral	-0,81	low_impact	1,74	neutral	0,81	neutral	0,52	deleterious	1,93	15,76	0,36	0,5	neutral	0,23	neutral	0,25	neutral	0,38	neutral	0,44	1	neutral	0,72	neutral	0,37	neutral	-3	neutral	0,42	medium_impact	-0,81	medium_impact	-0,01	medium_impact	0,39	0,62	0,8	21,89	13,98	N	0,39	N	0,34	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14119	14119	C	T	MI.23053	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1783	595	L	F	Ctc/Ttc	-6,94	0	0	possibly_damaging	0,54	neutral	0,32	neutral	0,73	neutral	-2,72	neutral	-1,83	low_impact	1,9	neutral	0,77	neutral	0,44	deleterious	2,44	19,1	0,35	0,5	neutral	0,35	neutral	0,39	neutral	0,43	neutral	0,47	1	neutral	0,67	neutral	0,39	neutral	-3	deleterious	0,45	medium_impact	-0,81	medium_impact	0,05	medium_impact	0,53	0,59	0,8	21,89	13,98	N	0,38	N	0,28	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14120	14120	T	C	MI.23054	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1784	595	L	P	cTc/cCc	-6,25	0	0	possibly_damaging	0,54	neutral	0,11	neutral	0,69	deleterious	-4,46	deleterious	-3,47	low_impact	1,47	neutral	0,64	neutral	0,44	deleterious	2,45	19,12	0,16	0,45	disease	0,77	disease	0,75	disease	0,73	disease	0,76	5	neutral	0,88	neutral	0,29	neutral	-3	deleterious	0,59	medium_impact	-0,81	medium_impact	-0,27	medium_impact	0,14	0,63	0,8	21,89	13,98	N	0,27	N	0,9	polymorphism	1	0,34	.	.	.	.	.	.	COSM488757	.	.	.	.	.	.	.	.
chrM	14120	14120	T	G	MI.23055	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1784	595	L	R	cTc/cGc	-6,25	0	0	possibly_damaging	0,54	neutral	0,15	neutral	0,7	deleterious	-3,87	deleterious	-3,34	medium_impact	2,71	neutral	0,66	damaging	0,18	deleterious	3,83	23,4	0,15	0,45	disease	0,7	disease	0,8	disease	0,73	disease	0,79	6	neutral	0,84	neutral	0,31	NA	0	deleterious	0,58	medium_impact	-0,81	medium_impact	-0,18	medium_impact	1,27	0,68	0,85	21,89	13,98	N	0,24	N	0,88	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14120	14120	T	A	MI.23056	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1784	595	L	H	cTc/cAc	-6,25	0	0	possibly_damaging	0,54	neutral	0,23	neutral	0,69	deleterious	-4,41	deleterious	-3,75	medium_impact	2,71	neutral	0,73	damaging	0,25	deleterious	2,89	21,8	0,21	0,45	disease	0,77	disease	0,6	disease	0,7	disease	0,74	5	neutral	0,76	neutral	0,35	NA	0	deleterious	0,54	medium_impact	-0,81	medium_impact	-0,06	medium_impact	1,27	0,66	0,8	21,89	13,98	N	0,28	N	0,8	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14122	14122	A	T	MI.23057	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1786	596	I	F	Atc/Ttc	-8,77	0	0,01	benign	0,17	neutral	0,62	neutral	0,86	neutral	-1,18	neutral	-1,6	low_impact	1,31	neutral	0,79	neutral	0,8	deleterious	0,42	6,82	0,33	0,5	neutral	0,42	neutral	0,38	neutral	0,37	neutral	0,44	1	neutral	0,26	deleterious	0,73	neutral	-6	neutral	0,32	medium_impact	-0,09	medium_impact	0,35	medium_impact	-0,01	0,6	0,8	5,97	9,95	N	0,29	N	0,39	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14122	14122	A	C	MI.23058	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1786	596	I	L	Atc/Ctc	-8,77	0	0,01	benign	0,17	neutral	1	neutral	1,1	neutral	0,5	neutral	0,04	neutral_impact	-0,48	neutral	0,82	neutral	0,98	neutral	-0,16	1,32	0,29	0,45	neutral	0,23	neutral	0,12	neutral	0,27	neutral	0,24	5	neutral	0,17	deleterious	0,92	neutral	-6	neutral	0,26	medium_impact	-0,09	high_impact	1,89	low_impact	-1,64	0,46	0,8	5,97	9,95	N	0,32	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14122	14122	A	G	MI.23059	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1786	596	I	V	Atc/Gtc	-8,77	0	0,01	benign	0,17	neutral	0,48	neutral	0,91	neutral	-0,64	neutral	0,1	low_impact	1,07	neutral	0,86	neutral	0,96	neutral	-0,41	0,37	0,46	0,55	neutral	0,3	neutral	0,1	neutral	0,35	neutral	0,31	4	neutral	0,43	deleterious	0,66	neutral	-6	neutral	0,27	medium_impact	-0,09	medium_impact	0,21	medium_impact	-0,23	0,55	0,8	5,97	9,95	N	0,4	N	0,37	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6104	6104	C	A	MI.2306	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	201	67	F	L	ttC/ttA	5,91	1	0	benign	0,13	deleterious	0	neutral	2,42	neutral	-2,22	deleterious	-3,86	medium_impact	3,04	neutral	0,66	damaging	0,15	deleterious	4,55	24,4	0,33	0,55	neutral	0,33	disease	0,78	disease	0,59	disease	0,65	3	deleterious	1	neutral	0,44	deleterious	1	neutral	0,25	medium_impact	0,02	low_impact	-1,48	medium_impact	1,71	0,56	0,9	1,17	6,64	N	0,5	N	0,83	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14123	14123	T	C	MI.23060	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1787	596	I	T	aTc/aCc	-3,27	0	0	benign	0,17	neutral	0,53	neutral	0,85	neutral	-1,25	neutral	0,94	neutral_impact	0,32	neutral	0,9	neutral	0,99	neutral	-0,99	0,02	0,34	0,5	neutral	0,43	neutral	0,07	neutral	0,35	neutral	0,3	4	neutral	0,37	deleterious	0,68	neutral	-6	neutral	0,29	medium_impact	-0,09	medium_impact	0,26	medium_impact	-0,91	0,57	0,8	5,97	9,95	N	0,39	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14123	14123	T	G	MI.23061	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1787	596	I	S	aTc/aGc	-3,27	0	0	benign	0,17	neutral	0,61	neutral	0,79	neutral	-2,54	neutral	-0,69	low_impact	1,31	neutral	0,87	neutral	0,9	deleterious	0,88	9,95	0,26	0,45	neutral	0,48	neutral	0,35	neutral	0,43	neutral	0,41	2	neutral	0,28	deleterious	0,72	neutral	-6	neutral	0,32	medium_impact	-0,09	medium_impact	0,34	medium_impact	-0,01	0,62	0,8	5,97	9,95	N	0,31	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14123	14123	T	A	MI.23062	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1787	596	I	N	aTc/aAc	-3,27	0	0	benign	0,17	neutral	0,29	neutral	0,76	deleterious	-3,78	neutral	-1,79	medium_impact	2,36	neutral	0,74	neutral	0,58	neutral	1,49	13,26	0,22	0,45	disease	0,7	disease	0,54	disease	0,52	disease	0,6	2	neutral	0,66	deleterious	0,56	neutral	-3	neutral	0,39	medium_impact	-0,09	medium_impact	0,02	medium_impact	0,95	0,67	0,85	5,97	9,95	N	0,34	N	0,5	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14124	14124	C	G	MI.23063	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1788	596	I	M	atC/atG	-3,04	0	0	benign	0,17	neutral	0,24	neutral	0,81	neutral	-2,01	neutral	-0,15	neutral_impact	0,73	neutral	0,82	neutral	0,98	deleterious	0,23	4,96	0,39	0,5	neutral	0,38	neutral	0,13	neutral	0,34	neutral	0,32	4	neutral	0,72	deleterious	0,54	neutral	-6	neutral	0,28	medium_impact	-0,09	medium_impact	-0,04	medium_impact	-0,54	0,68	0,85	5,97	9,95	N	0,45	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14124	14124	C	A	MI.23064	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1788	596	I	M	atC/atA	-3,04	0	0	benign	0,17	neutral	0,24	neutral	0,81	neutral	-2,01	neutral	-0,15	neutral_impact	0,73	neutral	0,82	neutral	0,98	deleterious	0,7	8,85	0,39	0,5	neutral	0,38	neutral	0,13	neutral	0,34	neutral	0,32	4	neutral	0,72	deleterious	0,54	neutral	-6	neutral	0,28	medium_impact	-0,09	medium_impact	-0,04	medium_impact	-0,54	0,68	0,85	5,97	9,95	N	0,45	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14125	14125	C	A	MI.23065	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1789	597	L	M	Cta/Ata	-9,69	0	0	possibly_damaging	0,54	neutral	0,24	neutral	0,72	neutral	-2,93	neutral	-0,94	low_impact	1,12	neutral	0,84	neutral	0,92	deleterious	2,17	17,34	0,29	0,45	disease	0,53	neutral	0,12	neutral	0,37	neutral	0,26	5	neutral	0,75	neutral	0,35	neutral	-3	neutral	0,43	medium_impact	-0,81	medium_impact	-0,04	medium_impact	-0,18	0,71	0,85	9,78	14,92	N	0,47	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14125	14125	C	G	MI.23066	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1789	597	L	V	Cta/Gta	-9,69	0	0	possibly_damaging	0,54	neutral	0,37	neutral	0,84	neutral	-1,36	neutral	-1,17	medium_impact	2,12	neutral	0,87	neutral	0,97	deleterious	2,03	16,37	0,3	0,45	neutral	0,28	neutral	0,21	neutral	0,41	neutral	0,39	2	neutral	0,62	neutral	0,42	NA	0	neutral	0,43	medium_impact	-0,81	medium_impact	0,11	medium_impact	0,73	0,54	0,8	9,78	14,92	N	0,42	N	0,55	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14126	14126	T	C	MI.23067	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1790	597	L	P	cTa/cCa	-5,56	0	0	possibly_damaging	0,54	neutral	0,12	neutral	0,66	deleterious	-5,19	deleterious	-4,2	medium_impact	3,23	damaging	0,55	neutral	0,44	deleterious	3,64	23,2	0,21	0,45	disease	0,7	disease	0,7	disease	0,73	disease	0,75	5	neutral	0,87	neutral	0,29	NA	0	deleterious	0,58	medium_impact	-0,81	medium_impact	-0,25	medium_impact	1,75	0,5	0,8	9,78	14,92	N	0,34	N	0,94	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14126	14126	T	A	MI.23068	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1790	597	L	Q	cTa/cAa	-5,56	0	0	possibly_damaging	0,54	neutral	0,23	neutral	0,67	deleterious	-4,45	deleterious	-3,78	medium_impact	3,23	neutral	0,72	neutral	0,61	deleterious	3,81	23,4	0,2	0,45	disease	0,58	disease	0,52	disease	0,61	disease	0,69	4	neutral	0,76	neutral	0,35	NA	0	deleterious	0,48	medium_impact	-0,81	medium_impact	-0,06	medium_impact	1,75	0,66	0,8	9,78	14,92	N	0,37	N	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14126	14126	T	G	MI.23069	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1790	597	L	R	cTa/cGa	-5,56	0	0	possibly_damaging	0,54	neutral	0,25	neutral	0,67	deleterious	-4,43	deleterious	-4,03	medium_impact	3,23	neutral	0,63	neutral	0,47	deleterious	3,88	23,5	0,2	0,45	neutral	0,45	disease	0,76	disease	0,73	disease	0,75	5	neutral	0,74	neutral	0,36	NA	0	deleterious	0,54	medium_impact	-0,81	medium_impact	-0,03	medium_impact	1,75	0,58	0,8	9,78	14,92	N	0,36	N	0,98	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6104	6104	C	G	MI.2307	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	201	67	F	L	ttC/ttG	5,91	1	0	benign	0,13	deleterious	0	neutral	2,42	neutral	-2,22	deleterious	-3,86	medium_impact	3,04	neutral	0,66	damaging	0,15	deleterious	4,25	23,9	0,33	0,55	neutral	0,33	disease	0,78	disease	0,59	disease	0,65	3	deleterious	1	neutral	0,44	deleterious	1	neutral	0,25	medium_impact	0,02	low_impact	-1,48	medium_impact	1,71	0,56	0,9	1,17	6,64	N	0,5	N	0,83	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14128	14128	A	G	MI.23070	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1792	598	T	A	Acc/Gcc	-1,67	0	0	possibly_damaging	0,54	neutral	0,51	neutral	1,07	neutral	0,91	neutral	0,66	neutral_impact	0,34	neutral	0,86	neutral	0,99	deleterious	0,5	7,46	0,56	0,6	neutral	0,25	neutral	0,04	neutral	0,27	neutral	0,18	6	neutral	0,52	deleterious	0,49	neutral	-3	neutral	0,35	medium_impact	-0,81	medium_impact	0,24	medium_impact	-0,89	0,53	0,8	26,2	22,65	N	0,4	N	0,04	polymorphism	1	0	rs386829201	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14128	14128	A	C	MI.23071	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1792	598	T	P	Acc/Ccc	-1,67	0	0	possibly_damaging	0,54	neutral	0,15	neutral	0,95	neutral	-1,44	neutral	-1,45	medium_impact	2,14	neutral	0,68	neutral	0,52	deleterious	2,12	16,99	0,19	0,45	neutral	0,49	disease	0,59	disease	0,58	disease	0,72	4	neutral	0,84	neutral	0,31	NA	0	deleterious	0,46	medium_impact	-0,81	medium_impact	-0,18	medium_impact	0,75	0,7	0,85	26,2	22,65	N	0,35	N	0,38	polymorphism	1	0,04	rs386829201	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14128	14128	A	T	MI.23072	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1792	598	T	S	Acc/Tcc	-1,67	0	0	possibly_damaging	0,54	neutral	0,48	neutral	0,99	neutral	-0,14	neutral	0,45	low_impact	0,82	neutral	0,83	neutral	0,99	neutral	1,06	11,01	0,4	0,5	neutral	0,15	neutral	0,07	neutral	0,3	neutral	0,27	5	neutral	0,54	deleterious	0,47	neutral	-3	neutral	0,34	medium_impact	-0,81	medium_impact	0,21	medium_impact	-0,45	0,68	0,85	26,2	22,65	N	0,41	N	0,03	polymorphism	1	0,01	rs386829201	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14129	14129	C	A	MI.23073	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1793	598	T	N	aCc/aAc	-0,75	0	0	possibly_damaging	0,54	neutral	0,25	neutral	0,94	neutral	-1,97	neutral	-1,32	medium_impact	2,14	neutral	0,8	neutral	0,61	deleterious	3,7	23,3	0,47	0,55	neutral	0,26	neutral	0,34	neutral	0,43	neutral	0,46	1	neutral	0,74	neutral	0,36	NA	0	neutral	0,38	medium_impact	-0,81	medium_impact	-0,03	medium_impact	0,75	0,7	0,85	26,2	22,65	N	0,39	N	0,34	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14129	14129	C	G	MI.23074	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1793	598	T	S	aCc/aGc	-0,75	0	0	possibly_damaging	0,54	neutral	0,48	neutral	0,99	neutral	-0,14	neutral	0,45	low_impact	0,82	neutral	0,83	neutral	0,99	neutral	1,5	13,32	0,4	0,5	neutral	0,15	neutral	0,07	neutral	0,3	neutral	0,27	5	neutral	0,54	deleterious	0,47	neutral	-3	neutral	0,34	medium_impact	-0,81	medium_impact	0,21	medium_impact	-0,45	0,68	0,85	26,2	22,65	N	0,44	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14129	14129	C	T	MI.23075	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1793	598	T	I	aCc/aTc	-0,75	0	0	possibly_damaging	0,54	neutral	0,53	neutral	1,15	neutral	1,58	neutral	-1,38	neutral_impact	0,34	neutral	0,84	neutral	0,97	deleterious	2,3	18,17	0,33	0,5	neutral	0,46	neutral	0,14	neutral	0,33	neutral	0,3	4	neutral	0,51	deleterious	0,5	neutral	-3	neutral	0,37	medium_impact	-0,81	medium_impact	0,26	medium_impact	-0,89	0,66	0,8	26,2	22,65	N	0,3	N	0,04	polymorphism	1	0,03	rs879039557	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14131	14131	C	G	MI.23076	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1795	599	L	V	Cta/Gta	-7,4	0	0	possibly_damaging	0,54	neutral	0,59	neutral	0,81	neutral	-1,26	neutral	-1,1	low_impact	1,7	neutral	0,83	neutral	0,87	neutral	1,73	14,56	0,35	0,5	neutral	0,22	neutral	0,1	neutral	0,34	neutral	0,32	4	neutral	0,48	deleterious	0,53	neutral	-3	neutral	0,41	medium_impact	-0,81	medium_impact	0,32	medium_impact	0,35	0,64	0,8	17,74	14,51	N	0,36	N	0,39	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14131	14131	C	A	MI.23077	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1795	599	L	M	Cta/Ata	-7,4	0	0	possibly_damaging	0,54	neutral	0,37	neutral	0,77	neutral	-2,6	neutral	-0,71	low_impact	1,04	neutral	0,81	neutral	1	deleterious	1,92	15,69	0,21	0,45	neutral	0,28	neutral	0,05	neutral	0,27	neutral	0,24	5	neutral	0,62	neutral	0,42	neutral	-3	neutral	0,4	medium_impact	-0,81	medium_impact	0,11	medium_impact	-0,25	0,52	0,8	17,74	14,51	N	0,48	N	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14132	14132	T	C	MI.23078	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1796	599	L	P	cTa/cCa	-8,54	0	0	possibly_damaging	0,54	neutral	0,13	neutral	0,68	deleterious	-4,76	deleterious	-3,41	medium_impact	1,98	neutral	0,76	neutral	0,78	deleterious	2,7	20,8	0,2	0,45	disease	0,67	disease	0,56	disease	0,7	disease	0,69	4	neutral	0,86	neutral	0,3	NA	0	deleterious	0,56	medium_impact	-0,81	medium_impact	-0,22	medium_impact	0,61	0,51	0,8	17,74	14,51	N	0,33	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14132	14132	T	A	MI.23079	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1796	599	L	Q	cTa/cAa	-8,54	0	0	possibly_damaging	0,54	neutral	0,28	neutral	0,68	deleterious	-4,12	deleterious	-3,21	medium_impact	2,67	neutral	0,75	neutral	0,65	deleterious	3,97	23,6	0,21	0,45	disease	0,61	neutral	0,36	disease	0,57	disease	0,64	3	neutral	0,71	neutral	0,37	NA	0	deleterious	0,48	medium_impact	-0,81	medium_impact	0,01	medium_impact	1,24	0,61	0,8	17,74	14,51	N	0,37	N	0,85	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6105	6105	T	C	MI.2308	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	202	68	F	L	Ttc/Ctc	0,59	0,99	0	probably_damaging	1	deleterious	0	neutral	2,84	neutral	-2,72	deleterious	-3,87	medium_impact	3,06	damaging	0,57	damaging	0,18	deleterious	3,87	23,5	0,34	0,55	neutral	0,26	disease	0,81	disease	0,59	disease	0,69	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	medium_impact	1,73	0,68	0,9	3,9	6,74	N	0,4	N	0,83	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14132	14132	T	G	MI.23080	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1796	599	L	R	cTa/cGa	-8,54	0	0	possibly_damaging	0,54	neutral	0,22	neutral	0,69	deleterious	-4,11	deleterious	-3,37	medium_impact	2,67	neutral	0,66	neutral	0,54	deleterious	4,13	23,8	0,22	0,45	disease	0,58	disease	0,61	disease	0,69	disease	0,74	5	neutral	0,77	neutral	0,34	NA	0	deleterious	0,55	medium_impact	-0,81	medium_impact	-0,07	medium_impact	1,24	0,57	0,8	17,74	14,51	N	0,33	N	0,87	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14134	14134	C	G	MI.23081	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1798	600	L	V	Ctc/Gtc	-3,96	0	0	possibly_damaging	0,54	neutral	0,19	neutral	0,81	neutral	-1,18	neutral	-1,11	low_impact	1,25	neutral	0,91	neutral	0,96	deleterious	2,25	17,86	0,35	0,5	neutral	0,27	neutral	0,12	neutral	0,4	neutral	0,3	4	neutral	0,8	neutral	0,33	neutral	-3	neutral	0,42	medium_impact	-0,81	medium_impact	-0,12	medium_impact	-0,06	0,57	0,8	12,77	11,85	N	0,51	P	0,33	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14134	14134	C	T	MI.23082	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1798	600	L	F	Ctc/Ttc	-3,96	0	0	possibly_damaging	0,54	neutral	0,46	neutral	0,71	neutral	-2,99	neutral	-1,66	low_impact	1,16	neutral	0,86	neutral	0,97	deleterious	2,77	21,2	0,29	0,45	neutral	0,22	neutral	0,17	neutral	0,4	neutral	0,31	4	neutral	0,55	neutral	0,46	neutral	-3	neutral	0,42	medium_impact	-0,81	medium_impact	0,19	medium_impact	-0,14	0,57	0,8	12,77	11,85	N	0,36	N	0,14	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14134	14134	C	A	MI.23083	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1798	600	L	I	Ctc/Atc	-3,96	0	0	possibly_damaging	0,54	neutral	0,53	neutral	0,83	neutral	-0,71	neutral	-0,56	low_impact	0,95	neutral	0,84	neutral	0,98	deleterious	2,21	17,6	0,34	0,5	neutral	0,27	neutral	0,06	neutral	0,3	neutral	0,24	5	neutral	0,51	deleterious	0,5	neutral	-3	neutral	0,41	medium_impact	-0,81	medium_impact	0,26	medium_impact	-0,34	0,57	0,8	12,77	11,85	N	0,38	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14135	14135	T	G	MI.23084	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1799	600	L	R	cTc/cGc	-5,33	0	0	possibly_damaging	0,54	neutral	0,09	neutral	0,65	deleterious	-4,19	deleterious	-3,56	medium_impact	2,4	neutral	0,65	neutral	0,51	deleterious	4,08	23,7	0,21	0,45	disease	0,53	disease	0,62	disease	0,72	disease	0,75	5	neutral	0,9	neutral	0,28	NA	0	deleterious	0,54	medium_impact	-0,81	medium_impact	-0,32	medium_impact	0,99	0,54	0,8	12,77	11,85	N	0,33	N	0,81	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14135	14135	T	C	MI.23085	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1799	600	L	P	cTc/cCc	-5,33	0	0	possibly_damaging	0,54	neutral	0,08	neutral	0,65	deleterious	-5,03	deleterious	-3,89	medium_impact	2,4	damaging	0,56	neutral	0,47	deleterious	3,87	23,5	0,21	0,45	disease	0,64	disease	0,56	disease	0,72	disease	0,74	5	neutral	0,91	neutral	0,27	NA	0	deleterious	0,55	medium_impact	-0,81	medium_impact	-0,35	medium_impact	0,99	0,64	0,8	12,77	11,85	N	0,33	N	0,88	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14135	14135	T	A	MI.23086	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1799	600	L	H	cTc/cAc	-5,33	0	0	possibly_damaging	0,54	neutral	0,14	neutral	0,64	deleterious	-5,12	deleterious	-3,93	medium_impact	2,4	neutral	0,73	neutral	0,58	deleterious	4,21	23,9	0,19	0,45	disease	0,63	neutral	0,42	disease	0,69	disease	0,66	3	neutral	0,85	neutral	0,3	NA	0	deleterious	0,51	medium_impact	-0,81	medium_impact	-0,2	medium_impact	0,99	0,46	0,8	12,77	11,85	N	0,36	N	0,75	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14137	14137	C	A	MI.23087	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1801	601	L	M	Cta/Ata	-9,69	0	0	possibly_damaging	0,54	neutral	0,2	neutral	0,8	neutral	-2,71	neutral	-0,47	low_impact	0,8	neutral	0,85	neutral	0,94	deleterious	2,09	16,82	0,23	0,45	neutral	0,44	neutral	0,06	neutral	0,29	neutral	0,23	5	neutral	0,79	neutral	0,33	neutral	-3	neutral	0,42	medium_impact	-0,81	medium_impact	-0,1	medium_impact	-0,47	0,65	0,8	NA	NA	N	0,51	P	0,02	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14137	14137	C	G	MI.23088	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1801	601	L	V	Cta/Gta	-9,69	0	0	possibly_damaging	0,54	neutral	0,24	neutral	0,81	neutral	-1,35	neutral	-0,96	low_impact	0,8	neutral	0,87	neutral	0,95	deleterious	2,15	17,2	0,28	0,45	neutral	0,27	neutral	0,09	neutral	0,35	neutral	0,27	5	neutral	0,75	neutral	0,35	neutral	-3	neutral	0,42	medium_impact	-0,81	medium_impact	-0,04	medium_impact	-0,47	0,39	0,8	NA	NA	N	0,51	P	0,34	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14138	14138	T	A	MI.23089	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1802	601	L	Q	cTa/cAa	-8,54	0	0	possibly_damaging	0,54	neutral	0,14	neutral	0,68	deleterious	-4,26	deleterious	-3,46	low_impact	0,8	neutral	0,71	damaging	0,26	deleterious	3,95	23,6	0,21	0,45	neutral	0,4	neutral	0,33	disease	0,55	neutral	0,49	0	neutral	0,85	neutral	0,3	neutral	-3	deleterious	0,46	medium_impact	-0,81	medium_impact	-0,2	medium_impact	-0,47	0,56	0,8	NA	NA	N	0,3	N	0,72	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6105	6105	T	G	MI.2309	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	202	68	F	V	Ttc/Gtc	0,59	0,99	0	probably_damaging	1	deleterious	0	neutral	2,81	deleterious	-3,64	deleterious	-4,51	high_impact	4,41	neutral	0,64	damaging	0,15	deleterious	3,89	23,5	0,21	0,55	disease	0,64	disease	0,92	disease	0,69	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,97	0,61	0,9	3,9	6,74	N	0,5	N	0,84	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14138	14138	T	G	MI.23090	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1802	601	L	R	cTa/cGa	-8,54	0	0	possibly_damaging	0,54	neutral	0,12	neutral	0,68	deleterious	-4,2	deleterious	-3,74	low_impact	0,8	neutral	0,65	damaging	0,18	deleterious	4,02	23,6	0,21	0,45	neutral	0,31	disease	0,55	disease	0,66	disease	0,69	4	neutral	0,87	neutral	0,29	neutral	-3	deleterious	0,5	medium_impact	-0,81	medium_impact	-0,25	medium_impact	-0,47	0,52	0,8	NA	NA	N	0,27	N	0,81	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14138	14138	T	C	MI.23091	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1802	601	L	P	cTa/cCa	-8,54	0	0	possibly_damaging	0,54	neutral	0,05	neutral	0,68	deleterious	-5,13	deleterious	-3,97	low_impact	0,8	damaging	0,57	damaging	0,17	deleterious	3,77	23,4	0,18	0,45	neutral	0,43	neutral	0,49	disease	0,67	disease	0,68	4	neutral	0,95	neutral	0,26	neutral	-3	deleterious	0,52	medium_impact	-0,81	medium_impact	-0,47	medium_impact	-0,47	0,46	0,8	NA	NA	N	0,28	N	0,88	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14140	14140	A	G	MI.23092	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1804	602	I	V	Atc/Gtc	-1,21	0	0	benign	0,17	neutral	0,53	neutral	0,93	neutral	-0,6	neutral	-0,29	neutral_impact	0	neutral	0,91	neutral	0,92	neutral	-0,17	1,26	0,53	0,6	neutral	0,23	neutral	0,02	neutral	0,39	neutral	0,18	6	neutral	0,37	deleterious	0,68	neutral	-6	neutral	0,24	medium_impact	-0,09	medium_impact	0,26	low_impact	-1,2	0,31	0,8	NA	NA	N	0,42	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14140	14140	A	C	MI.23093	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1804	602	I	L	Atc/Ctc	-1,21	0	0	benign	0,17	neutral	0,72	neutral	0,98	neutral	-0,16	neutral	-0,07	neutral_impact	0	neutral	0,87	neutral	0,99	neutral	-0,48	0,25	0,38	0,5	neutral	0,21	neutral	0,03	neutral	0,29	neutral	0,14	7	neutral	0,16	deleterious	0,78	neutral	-6	neutral	0,25	medium_impact	-0,09	medium_impact	0,46	low_impact	-1,2	0,59	0,8	NA	NA	N	0,43	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14140	14140	A	T	MI.23094	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1804	602	I	F	Atc/Ttc	-1,21	0	0	benign	0,17	neutral	0,75	neutral	0,89	neutral	-1,03	neutral	-1,2	neutral_impact	0	neutral	0,89	neutral	0,91	neutral	1,1	11,2	0,46	0,55	neutral	0,19	neutral	0,15	neutral	0,46	neutral	0,23	5	neutral	0,14	deleterious	0,79	neutral	-6	neutral	0,26	medium_impact	-0,09	medium_impact	0,5	low_impact	-1,2	0,55	0,8	NA	NA	N	0,34	N	0,09	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14141	14141	T	A	MI.23095	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1805	602	I	N	aTc/aAc	-8,08	0	0	benign	0,17	neutral	0,31	neutral	0,82	neutral	-2,41	deleterious	-3,01	neutral_impact	0	neutral	0,7	neutral	0,61	deleterious	2,95	22,1	0,36	0,5	disease	0,51	neutral	0,27	disease	0,62	neutral	0,38	2	neutral	0,63	deleterious	0,57	neutral	-6	neutral	0,34	medium_impact	-0,09	medium_impact	0,04	low_impact	-1,2	0,52	0,8	NA	NA	N	0,35	N	0,39	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14141	14141	T	C	MI.23096	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1805	602	I	T	aTc/aCc	-8,08	0	0	benign	0,17	neutral	0,55	neutral	0,91	neutral	-0,75	neutral	-1,23	neutral_impact	0	neutral	0,89	neutral	0,86	deleterious	0,73	9,01	0,44	0,55	neutral	0,32	neutral	0,09	neutral	0,44	neutral	0,2	6	neutral	0,34	deleterious	0,69	neutral	-6	neutral	0,27	medium_impact	-0,09	medium_impact	0,28	low_impact	-1,2	0,33	0,8	NA	NA	N	0,36	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14141	14141	T	G	MI.23097	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1805	602	I	S	aTc/aGc	-8,08	0	0	benign	0,17	neutral	0,43	neutral	0,86	neutral	-1,56	neutral	-2,15	neutral_impact	0	neutral	0,85	neutral	0,83	neutral	1,57	13,69	0,36	0,5	neutral	0,35	neutral	0,23	disease	0,52	neutral	0,41	2	neutral	0,49	deleterious	0,63	neutral	-6	neutral	0,3	medium_impact	-0,09	medium_impact	0,17	low_impact	-1,2	0,47	0,8	NA	NA	N	0,32	N	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14142	14142	C	G	MI.23098	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1806	602	I	M	atC/atG	-0,98	0	0	benign	0,17	neutral	0,25	neutral	0,91	neutral	-0,74	neutral	-0,38	neutral_impact	0	neutral	0,88	neutral	0,91	deleterious	-0,01	2,47	0,55	0,6	neutral	0,38	neutral	0,05	neutral	0,39	neutral	0,18	6	neutral	0,71	deleterious	0,54	neutral	-6	neutral	0,28	medium_impact	-0,09	medium_impact	-0,03	low_impact	-1,2	0,61	0,8	NA	NA	N	0,5	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14142	14142	C	A	MI.23099	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1806	602	I	M	atC/atA	-0,98	0	0	benign	0,17	neutral	0,25	neutral	0,91	neutral	-0,74	neutral	-0,38	neutral_impact	0	neutral	0,88	neutral	0,91	deleterious	0,41	6,7	0,55	0,6	neutral	0,38	neutral	0,05	neutral	0,39	neutral	0,18	6	neutral	0,71	deleterious	0,54	neutral	-6	neutral	0,28	medium_impact	-0,09	medium_impact	-0,03	low_impact	-1,2	0,61	0,8	NA	NA	N	0,5	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8635	8635	C	T	MI.231	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	109	37	L	F	Ctc/Ttc	-1,26	0	0	benign	0,03	neutral	0,44	neutral	4,28	neutral	-2,25	neutral	-1,26	low_impact	1,08	neutral	0,88	neutral	0,67	neutral	1,76	14,75	0,51	0,65	disease	0,55	neutral	0,5	disease	0,55	disease	0,52	0	neutral	0,53	deleterious	0,71	neutral	-6	neutral	0,25	medium_impact	0,68	medium_impact	0,23	medium_impact	-0,17	0,58	0,9	20,35	20,89	N	0,28	N	0,48	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6105	6105	T	A	MI.2310	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	202	68	F	I	Ttc/Atc	0,59	0,99	0	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-3,75	deleterious	-3,87	high_impact	5,1	neutral	0,71	damaging	0,17	deleterious	4,2	23,9	0,19	0,55	disease	0,61	disease	0,91	disease	0,67	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,61	0,59	0,9	3,9	6,74	P	0,69	P	0,88	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14143	14143	A	C	MI.23100	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1807	603	T	P	Aca/Cca	-5,79	0	0	unknown	NA	neutral	0,21	neutral	3,71	neutral	-1,8	neutral	-2,16	neutral_impact	0	damaging	0,37	damaging	0,28	deleterious	2,22	17,64	0,25	0,45	NA	NA	neutral	0,32	neutral	0,5	neutral	0,22	6	neutral	0,79	deleterious	0,61	neutral	-4	neutral	0,37	high_impact	2,1	medium_impact	-0,09	low_impact	-1,2	0,77	0,85	NA	NA	P	0,56	P	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14143	14143	A	T	MI.23101	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1807	603	T	S	Aca/Tca	-5,79	0	0	unknown	NA	neutral	0,44	neutral	3,79	neutral	-0,21	neutral	-1,07	neutral_impact	0	neutral	0,79	neutral	0,95	deleterious	0,31	5,83	0,49	0,55	NA	NA	neutral	0,02	neutral	0,24	neutral	0,13	7	neutral	0,56	deleterious	0,72	neutral	-4	neutral	0,34	high_impact	2,1	medium_impact	0,18	low_impact	-1,2	0,76	0,85	NA	NA	N	0,43	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14143	14143	A	G	MI.23102	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1807	603	T	A	Aca/Gca	-5,79	0	0	unknown	NA	neutral	0,53	neutral	3,82	neutral	0,12	neutral	-1,03	neutral_impact	0	damaging	0,51	neutral	0,36	deleterious	2,21	17,57	0,53	0,6	NA	NA	neutral	0,09	neutral	0,49	neutral	0,14	7	neutral	0,47	deleterious	0,77	neutral	-4	neutral	0,37	high_impact	2,1	medium_impact	0,26	low_impact	-1,2	0,5	0,8	NA	NA	N	0,38	N	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14144	14144	C	T	MI.23103	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1808	603	T	M	aCa/aTa	-1,67	0	0	unknown	NA	neutral	0,23	neutral	3,71	neutral	-1,93	neutral	-0,01	neutral_impact	0	damaging	0,53	damaging	0,28	deleterious	2,8	21,3	0,37	0,5	NA	NA	neutral	0,2	neutral	0,38	neutral	0,27	5	neutral	0,77	deleterious	0,62	neutral	-4	neutral	0,39	high_impact	2,1	medium_impact	-0,06	low_impact	-1,2	0,72	0,85	NA	NA	N	0,45	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14144	14144	C	A	MI.23104	MT-ND5	I	ENSG00000198786	ENSP00000354813	ENST00000361567	NU5M_HUMAN	P03915	4540	YP_003024036.1	1808	603	T	K	aCa/aAa	-1,67	0	0	unknown	NA	neutral	0,29	neutral	3,76	neutral	-0,65	neutral	-1,95	neutral_impact	0	damaging	0,44	neutral	0,29	deleterious	3,25	22,8	0,27	0,45	NA	NA	neutral	0,31	disease	0,57	neutral	0,25	5	neutral	0,71	deleterious	0,65	neutral	-4	neutral	0,41	high_impact	2,1	medium_impact	0,02	low_impact	-1,2	0,49	0,8	NA	NA	N	0,46	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14152	14152	A	T	MI.23105	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	522	174	N	K	aaT/aaA	-0,06	0,06	0	probably_damaging	1	neutral	0,62	neutral	2,29	neutral	-0,63	deleterious	-3,04	low_impact	1,34	neutral	0,85	neutral	0,75	deleterious	4,07	23,7	0,66	0,7	neutral	0,19	neutral	0,39	neutral	0,43	neutral	0,36	3	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,86	low_impact	-3,55	medium_impact	0,32	medium_impact	-0,02	0,8	0,85	20,8	19,14	N	0,28	N	0,89	NA	NA	0,07	rs28357669	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14153	14153	T	C	MI.23106	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	521	174	N	S	aAt/aGt	0,4	0,01	0	probably_damaging	0,99	neutral	0,66	neutral	2,26	neutral	-1,06	neutral	-2,45	neutral_impact	0,69	neutral	0,89	neutral	0,87	neutral	1,31	12,34	0,59	0,65	neutral	0,12	neutral	0,17	neutral	0,27	neutral	0,17	7	deleterious	0,99	neutral	0,34	neutral	-2	deleterious	0,85	low_impact	-2,63	medium_impact	0,37	medium_impact	-0,56	0,71	0,85	20,8	19,14	N	0,35	N	0,68	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14153	14153	T	G	MI.23107	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	521	174	N	T	aAt/aCt	0,4	0,01	0	probably_damaging	0,99	neutral	0,59	neutral	2,24	neutral	-1,46	deleterious	-3,3	medium_impact	2,24	neutral	0,85	neutral	0,82	deleterious	3,67	23,3	0,45	0,55	neutral	0,24	neutral	0,28	neutral	0,43	neutral	0,34	3	deleterious	0,99	neutral	0,3	deleterious	1	deleterious	0,85	low_impact	-2,63	medium_impact	0,29	medium_impact	0,74	0,76	0,85	20,8	19,14	N	0,32	N	0,74	NA	NA	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14153	14153	T	A	MI.23108	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	521	174	N	I	aAt/aTt	0,4	0,01	0	probably_damaging	1	neutral	0,45	neutral	2,2	neutral	-2,44	deleterious	-5,38	low_impact	1,34	neutral	0,76	neutral	0,7	deleterious	4,31	24	0,38	0,5	neutral	0,44	neutral	0,45	neutral	0,44	neutral	0,42	2	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,87	low_impact	-3,55	medium_impact	0,16	medium_impact	-0,02	0,74	0,85	20,8	19,14	N	0,33	N	0,93	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14154	14154	T	C	MI.23109	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	520	174	N	D	Aat/Gat	-1,44	0	0	probably_damaging	0,99	neutral	0,42	neutral	2,28	neutral	-0,88	deleterious	-2,83	low_impact	1,9	neutral	0,89	neutral	0,86	deleterious	3,69	23,3	0,67	0,7	neutral	0,13	neutral	0,31	neutral	0,43	neutral	0,36	3	deleterious	0,99	neutral	0,22	neutral	-2	deleterious	0,85	low_impact	-2,63	medium_impact	0,13	medium_impact	0,45	0,73	0,85	20,8	19,14	N	0,42	N	0,81	NA	NA	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6106	6106	T	G	MI.2311	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	203	68	F	C	tTc/tGc	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-6,03	deleterious	-5,16	high_impact	4,75	neutral	0,67	damaging	0,14	deleterious	3,98	23,6	0,19	0,55	disease	0,91	disease	0,88	disease	0,69	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,44	0,9	3,9	6,74	P	0,66	P	0,91	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14154	14154	T	G	MI.23110	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	520	174	N	H	Aat/Cat	-1,44	0	0	probably_damaging	1	neutral	0,57	neutral	2,22	neutral	-1,29	deleterious	-2,78	low_impact	1,14	neutral	0,86	neutral	0,81	deleterious	3,55	23,1	0,47	0,55	neutral	0,38	neutral	0,11	neutral	0,29	neutral	0,16	7	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,86	low_impact	-3,55	medium_impact	0,27	medium_impact	-0,19	0,68	0,85	20,8	19,14	N	0,33	N	0,6	NA	NA	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14154	14154	T	A	MI.23111	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	520	174	N	Y	Aat/Tat	-1,44	0	0	probably_damaging	1	neutral	1	neutral	2,19	neutral	-2,48	deleterious	-4,57	low_impact	1,69	neutral	0,74	neutral	0,69	deleterious	4,38	24,1	0,38	0,5	disease	0,5	neutral	0,46	disease	0,54	neutral	0,4	2	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,87	low_impact	-3,55	high_impact	1,87	medium_impact	0,28	0,74	0,85	20,8	19,14	N	0,23	N	0,9	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14156	14156	C	G	MI.23112	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	518	173	G	A	gGg/gCg	-11,52	0	0	probably_damaging	1	neutral	0,86	neutral	1,06	deleterious	-5,15	deleterious	-5,1	medium_impact	3,26	neutral	0,62	damaging	0,16	deleterious	3,59	23,2	0,22	0,45	neutral	0,4	disease	0,5	disease	0,61	disease	0,64	3	deleterious	1	neutral	0,43	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	0,64	medium_impact	1,59	0,74	0,85	48,67	8,82	N	0,23	N	0,68	NA	NA	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14156	14156	C	A	MI.23113	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	518	173	G	V	gGg/gTg	-11,52	0	0	probably_damaging	1	neutral	0,61	neutral	1	deleterious	-6,53	deleterious	-7,78	medium_impact	3,46	damaging	0,38	damaging	0,05	deleterious	4,44	24,2	0,14	0,4	disease	0,6	disease	0,73	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,82	low_impact	-3,55	medium_impact	0,31	medium_impact	1,76	0,63	0,8	48,67	8,82	N	0,25	N	0,94	NA	NA	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14156	14156	C	T	MI.23114	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	518	173	G	E	gGg/gAg	-11,52	0	0	probably_damaging	1	neutral	1	neutral	1,01	deleterious	-6,13	deleterious	-6,7	medium_impact	3,46	damaging	0,52	damaging	0,06	deleterious	4,41	24,1	0,21	0,45	neutral	0,27	disease	0,73	disease	0,69	disease	0,69	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,78	low_impact	-3,55	high_impact	1,87	medium_impact	1,76	0,71	0,85	48,67	8,82	N	0,22	N	0,89	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14157	14157	C	A	MI.23115	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	517	173	G	W	Ggg/Tgg	3,15	0,84	0	probably_damaging	1	neutral	0,07	neutral	0,97	deleterious	-9,26	deleterious	-7,06	medium_impact	3,46	damaging	0,51	damaging	0,06	deleterious	5,11	25,3	0,17	0,45	disease	0,91	disease	0,76	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,85	low_impact	-3,55	medium_impact	-0,42	medium_impact	1,76	0,49	0,8	48,67	8,82	N	0,34	N	0,93	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14157	14157	C	G	MI.23116	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	517	173	G	R	Ggg/Cgg	3,15	0,84	0	probably_damaging	1	neutral	0,7	neutral	0,99	deleterious	-6,75	deleterious	-6,79	high_impact	3,81	damaging	0,47	damaging	0,05	deleterious	4,46	24,2	0,19	0,45	neutral	0,49	disease	0,68	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,8	low_impact	-3,55	medium_impact	0,41	high_impact	2,05	0,79	0,85	48,67	8,82	N	0,31	N	0,93	NA	NA	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14159	14159	C	G	MI.23117	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	515	172	R	P	cGg/cCg	-2,12	0	0	probably_damaging	1	neutral	0,29	neutral	1,68	deleterious	-6,48	deleterious	-6,96	high_impact	3,92	damaging	0,57	damaging	0,17	deleterious	4,75	24,7	0,51	0,6	disease	0,71	disease	0,86	disease	0,76	disease	0,8	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	-0,01	high_impact	2,14	0,69	0,85	49,56	8,68	N	0,36	N	0,98	NA	NA	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14159	14159	C	T	MI.23118	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	515	172	R	Q	cGg/cAg	-2,12	0	0	probably_damaging	1	neutral	0,6	neutral	1,73	deleterious	-5,02	deleterious	-3,95	high_impact	3,92	neutral	0,71	damaging	0,18	deleterious	5,08	25,3	0,66	0,7	neutral	0,48	disease	0,78	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,79	low_impact	-3,55	medium_impact	0,3	high_impact	2,14	0,97	1	49,56	8,68	N	0,3	N	0,99	NA	NA	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14159	14159	C	A	MI.23119	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	515	172	R	L	cGg/cTg	-2,12	0	0	probably_damaging	1	neutral	0,36	neutral	1,72	deleterious	-5,53	deleterious	-6,96	high_impact	3,58	damaging	0,59	damaging	0,21	deleterious	5,04	25,2	0,57	0,65	disease	0,6	disease	0,89	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	0,07	medium_impact	1,86	0,73	0,85	49,56	8,68	N	0,33	N	1	NA	NA	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6106	6106	T	C	MI.2312	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	203	68	F	S	tTc/tCc	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,66	deleterious	-4,42	deleterious	-5,16	high_impact	4,55	neutral	0,76	damaging	0,18	deleterious	4,14	23,8	0,22	0,55	disease	0,85	disease	0,86	disease	0,66	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,1	0,59	0,9	3,9	6,74	P	0,56	P	0,84	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14160	14160	G	A	MI.23120	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	514	172	R	W	Cgg/Tgg	3,15	0,99	0	probably_damaging	1	deleterious	0,02	neutral	1,67	deleterious	-8,34	deleterious	-7,95	high_impact	3,58	damaging	0,54	damaging	0,12	deleterious	5,14	25,4	0,46	0,55	disease	0,9	disease	0,85	disease	0,74	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,55	medium_impact	-0,73	medium_impact	1,86	0,84	0,9	49,56	8,68	N	0,43	N	1	NA	NA	0,28	.	.	.	.	.	.	COSM1155545	.	.	.	.	.	.	.	.
chrM	14160	14160	G	C	MI.23121	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	514	172	R	G	Cgg/Ggg	3,15	0,99	0	probably_damaging	1	neutral	0,39	neutral	1,69	deleterious	-5,75	deleterious	-6,96	high_impact	3,92	damaging	0,6	neutral	0,29	deleterious	4,23	23,9	0,54	0,6	disease	0,6	disease	0,76	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,8	low_impact	-3,55	medium_impact	0,1	high_impact	2,14	0,71	0,85	49,56	8,68	N	0,41	N	0,87	NA	NA	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14162	14162	G	T	MI.23122	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	512	171	A	D	gCt/gAt	-1,44	0	0,02	possibly_damaging	0,5	neutral	0,63	neutral	2,12	deleterious	-4,72	neutral	-1,27	low_impact	1,15	neutral	0,78	neutral	0,5	deleterious	4,02	23,6	0,39	0,5	neutral	0,36	disease	0,62	disease	0,56	disease	0,69	4	neutral	0,43	deleterious	0,57	neutral	-3	deleterious	0,49	medium_impact	-0,8	medium_impact	0,34	medium_impact	-0,18	0,63	0,8	17,26	16,43	N	0,19	N	0,79	NA	NA	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14162	14162	G	C	MI.23123	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	512	171	A	G	gCt/gGt	-1,44	0	0,02	benign	0,27	neutral	0,47	neutral	2,16	deleterious	-3,95	neutral	-2,16	low_impact	0,8	neutral	0,74	neutral	0,64	deleterious	2,35	18,52	0,41	0,5	neutral	0,32	neutral	0,34	neutral	0,49	neutral	0,45	1	neutral	0,43	deleterious	0,6	neutral	-6	neutral	0,31	medium_impact	-0,4	medium_impact	0,18	medium_impact	-0,47	0,84	0,9	17,26	16,43	N	0,35	N	0,53	NA	NA	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14162	14162	G	A	MI.23124	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	512	171	A	V	gCt/gTt	-1,44	0	0,02	benign	0,01	neutral	0,48	neutral	2,26	deleterious	-3,77	neutral	0,34	neutral_impact	-1,3	neutral	0,92	neutral	0,96	neutral	1,31	12,34	0,52	0,6	neutral	0,12	neutral	0,11	neutral	0,38	neutral	0,32	4	neutral	0,51	deleterious	0,74	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,19	low_impact	-2,23	0,75	0,85	17,26	16,43	N	0,39	N	0,18	NA	NA	0,18	.	.	.	.	.	.	COSM1155547	.	.	.	.	.	.	.	.
chrM	14163	14163	C	G	MI.23125	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	511	171	A	P	Gct/Cct	-0,06	0	0	possibly_damaging	0,66	neutral	0,35	neutral	2,12	deleterious	-5,07	neutral	-1,22	low_impact	1,15	neutral	0,76	neutral	0,42	deleterious	4,2	23,9	0,34	0,5	neutral	0,44	disease	0,68	disease	0,52	disease	0,61	2	neutral	0,71	neutral	0,35	neutral	-3	deleterious	0,61	low_impact	-1,06	medium_impact	0,06	medium_impact	-0,18	0,81	0,85	17,26	16,43	N	0,31	N	0,76	NA	NA	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14163	14163	C	T	MI.23126	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	511	171	A	T	Gct/Act	-0,06	0	0	benign	0,01	neutral	0,68	neutral	2,33	deleterious	-3,67	neutral	4,16	neutral_impact	-2,46	neutral	0,97	neutral	0,97	deleterious	0,12	3,79	0,61	0,65	neutral	0,09	neutral	0,03	neutral	0,31	neutral	0,17	7	neutral	0,31	deleterious	0,84	neutral	-6	neutral	0,1	medium_impact	1,03	medium_impact	0,39	low_impact	-3,2	0,85	0,9	17,26	16,43	N	0,33	N	0,24	NA	NA	0,18	.	.	.	.	.	.	.	.	.	C14163T	Possible deafness factor	+	-	Conflicting reports	2
chrM	14163	14163	C	A	MI.23127	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	511	171	A	S	Gct/Tct	-0,06	0	0	benign	0,2	neutral	0,85	neutral	2,35	deleterious	-3,23	neutral	0,64	neutral_impact	0,26	neutral	0,84	neutral	0,79	deleterious	2,83	21,5	0,47	0,55	neutral	0,21	neutral	0,29	neutral	0,33	neutral	0,42	2	neutral	0,1	deleterious	0,83	neutral	-6	neutral	0,26	medium_impact	-0,24	medium_impact	0,63	medium_impact	-0,92	0,76	0,85	17,26	16,43	N	0,25	N	0,58	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14164	14164	A	T	MI.23128	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	510	170	I	M	atT/atA	0,4	0	0	probably_damaging	0,92	neutral	0,11	neutral	1,86	deleterious	-4,19	deleterious	-2,65	medium_impact	2,49	neutral	0,79	neutral	0,66	deleterious	3,69	23,3	0,48	0,55	neutral	0,48	neutral	0,35	disease	0,54	neutral	0,47	1	neutral	0,97	neutral	0,1	deleterious	1	deleterious	0,69	low_impact	-1,77	medium_impact	-0,3	medium_impact	0,95	0,83	0,85	48,67	8,89	N	0,39	N	0,84	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14164	14164	A	C	MI.23129	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	510	170	I	M	atT/atG	0,4	0	0	probably_damaging	0,92	neutral	0,11	neutral	1,86	deleterious	-4,19	deleterious	-2,65	medium_impact	2,49	neutral	0,79	neutral	0,66	deleterious	3,54	23,1	0,48	0,55	neutral	0,48	neutral	0,35	disease	0,54	neutral	0,47	1	neutral	0,97	neutral	0,1	deleterious	1	deleterious	0,69	low_impact	-1,77	medium_impact	-0,3	medium_impact	0,95	0,83	0,85	48,67	8,89	N	0,39	N	0,84	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6106	6106	T	A	MI.2313	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	203	68	F	Y	tTc/tAc	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,65	neutral	-0,39	neutral	-1,93	high_impact	4	neutral	0,61	damaging	0,17	deleterious	4,13	23,8	0,26	0,55	disease	0,68	disease	0,83	disease	0,62	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,59	0,67	0,9	3,9	6,74	P	0,58	P	0,59	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14165	14165	A	G	MI.23130	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	509	170	I	T	aTt/aCt	-0,29	0	0	possibly_damaging	0,84	neutral	0,57	neutral	1,81	deleterious	-4,26	deleterious	-4,44	medium_impact	3,19	neutral	0,66	neutral	0,46	deleterious	3,93	23,5	0,42	0,55	disease	0,53	disease	0,5	disease	0,61	disease	0,69	4	neutral	0,82	neutral	0,37	NA	0	deleterious	0,73	low_impact	-1,46	medium_impact	0,27	medium_impact	1,53	0,65	0,8	48,67	8,89	N	0,31	N	0,91	NA	NA	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14165	14165	A	C	MI.23131	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	509	170	I	S	aTt/aGt	-0,29	0	0	probably_damaging	0,9	neutral	0,73	neutral	1,8	deleterious	-4,68	deleterious	-5,67	medium_impact	2,84	neutral	0,68	neutral	0,53	deleterious	4,37	24,1	0,3	0,45	disease	0,68	disease	0,72	disease	0,63	disease	0,73	5	neutral	0,89	neutral	0,42	deleterious	1	deleterious	0,81	low_impact	-1,67	medium_impact	0,45	medium_impact	1,24	0,53	0,8	48,67	8,89	N	0,3	N	0,97	NA	NA	0,69	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14165	14165	A	T	MI.23132	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	509	170	I	N	aTt/aAt	-0,29	0	0	probably_damaging	0,97	neutral	0,49	neutral	1,79	deleterious	-5,64	deleterious	-6,67	medium_impact	3,19	neutral	0,64	neutral	0,49	deleterious	4,56	24,4	0,28	0,45	disease	0,8	disease	0,74	disease	0,63	disease	0,76	5	neutral	0,97	neutral	0,26	deleterious	1	deleterious	0,84	low_impact	-2,18	medium_impact	0,2	medium_impact	1,53	0,58	0,8	48,67	8,89	N	0,31	N	0,99	NA	NA	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14166	14166	T	C	MI.23133	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	508	170	I	V	Att/Gtt	5,44	0,54	0	possibly_damaging	0,44	neutral	0,3	neutral	1,86	neutral	-1,8	neutral	-0,52	low_impact	1,02	neutral	0,89	neutral	0,98	neutral	1,69	14,36	0,46	0,55	neutral	0,11	neutral	0,11	neutral	0,34	neutral	0,29	4	neutral	0,66	neutral	0,43	neutral	-3	neutral	0,38	medium_impact	-0,7	medium_impact	0	medium_impact	-0,29	0,7	0,85	48,67	8,89	N	0,5	N	0,13	NA	NA	0,2	.	.	.	.	.	MNGIE fibroblasts	.	.	.	.	.	.	.	.	.
chrM	14166	14166	T	G	MI.23134	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	508	170	I	L	Att/Ctt	5,44	0,54	0	benign	0,03	neutral	0,35	neutral	2,14	neutral	-2,08	neutral	-1,86	neutral_impact	0,14	neutral	0,82	neutral	0,77	deleterious	3,28	22,8	0,37	0,5	neutral	0,14	neutral	0,11	neutral	0,29	neutral	0,23	5	neutral	0,63	deleterious	0,66	neutral	-6	neutral	0,12	medium_impact	0,59	medium_impact	0,06	low_impact	-1,02	0,68	0,85	48,67	8,89	N	0,49	N	0,63	NA	NA	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14166	14166	T	A	MI.23135	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	508	170	I	F	Att/Ttt	5,44	0,54	0	possibly_damaging	0,83	neutral	0,07	neutral	1,8	deleterious	-4,31	deleterious	-3,92	medium_impact	3,19	neutral	0,7	neutral	0,5	deleterious	4,64	24,5	0,37	0,5	disease	0,54	disease	0,67	disease	0,63	disease	0,73	5	neutral	0,96	neutral	0,12	NA	0	deleterious	0,75	low_impact	-1,43	medium_impact	-0,42	medium_impact	1,53	0,77	0,85	48,67	8,89	N	0,52	P	0,91	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14167	14167	C	A	MI.23136	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	507	169	E	D	gaG/gaT	-1,89	0	0,06	probably_damaging	1	neutral	0,53	neutral	2,25	deleterious	-3,1	deleterious	-2,95	medium_impact	2,94	neutral	0,8	neutral	0,38	deleterious	4,64	24,5	0,41	0,5	neutral	0,46	disease	0,82	disease	0,6	disease	0,66	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,83	low_impact	-3,55	medium_impact	0,24	medium_impact	1,32	0,83	0,9	50,88	8,57	N	0,22	N	0,83	NA	NA	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14167	14167	C	G	MI.23137	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	507	169	E	D	gaG/gaC	-1,89	0	0,06	probably_damaging	1	neutral	0,53	neutral	2,25	deleterious	-3,1	deleterious	-2,95	medium_impact	2,94	neutral	0,8	neutral	0,38	deleterious	4,23	23,9	0,41	0,5	neutral	0,46	disease	0,82	disease	0,6	disease	0,66	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,83	low_impact	-3,55	medium_impact	0,24	medium_impact	1,32	0,83	0,9	50,88	8,57	N	0,22	N	0,83	NA	NA	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14168	14168	T	C	MI.23138	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	506	169	E	G	gAg/gGg	-0,75	0	0	probably_damaging	1	neutral	0,58	neutral	2,25	deleterious	-4,34	deleterious	-6,86	medium_impact	3,21	neutral	0,71	neutral	0,52	deleterious	4,54	24,3	0,39	0,5	disease	0,6	disease	0,85	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,84	low_impact	-3,55	medium_impact	0,28	medium_impact	1,55	0,66	0,8	50,88	8,57	N	0,25	N	0,29	NA	NA	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14168	14168	T	G	MI.23139	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	506	169	E	A	gAg/gCg	-0,75	0	0	probably_damaging	1	neutral	1	neutral	2,34	deleterious	-3,9	deleterious	-5,86	high_impact	3,91	neutral	0,66	neutral	0,47	deleterious	4,4	24,1	0,35	0,5	neutral	0,48	disease	0,86	disease	0,66	disease	0,75	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,85	low_impact	-3,55	high_impact	1,87	high_impact	2,14	0,79	0,85	50,88	8,57	N	0,29	N	0,64	NA	NA	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6107	6107	C	G	MI.2314	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	204	68	F	L	ttC/ttG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,84	neutral	-2,72	deleterious	-3,87	medium_impact	3,06	damaging	0,57	damaging	0,18	deleterious	4,23	23,9	0,34	0,55	neutral	0,26	disease	0,81	disease	0,59	disease	0,69	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	medium_impact	1,73	0,68	0,9	3,9	6,74	N	0,47	N	0,83	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14168	14168	T	A	MI.23140	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	506	169	E	V	gAg/gTg	-0,75	0	0	probably_damaging	1	neutral	0,68	neutral	2,32	deleterious	-4,86	deleterious	-6,86	medium_impact	3,21	neutral	0,67	neutral	0,35	deleterious	4,86	24,9	0,3	0,45	disease	0,6	disease	0,94	disease	0,69	disease	0,83	7	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,88	low_impact	-3,55	medium_impact	0,39	medium_impact	1,55	0,81	0,85	50,88	8,57	N	0,3	N	0,72	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14169	14169	C	G	MI.23141	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	505	169	E	Q	Gag/Cag	1,77	0,06	0	probably_damaging	1	neutral	0,61	neutral	2,26	deleterious	-4,06	deleterious	-2,77	high_impact	3,56	neutral	0,79	neutral	0,39	deleterious	3,71	23,3	0,47	0,55	disease	0,51	disease	0,83	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,83	low_impact	-3,55	medium_impact	0,31	medium_impact	1,84	0,87	0,9	50,88	8,57	N	0,26	N	0,87	NA	NA	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14169	14169	C	T	MI.23142	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	505	169	E	K	Gag/Aag	1,77	0,06	0	probably_damaging	1	neutral	0,8	neutral	2,58	deleterious	-3,58	deleterious	-3,85	medium_impact	3,21	neutral	0,75	damaging	0,26	deleterious	4,88	24,9	0,38	0,5	neutral	0,42	disease	0,93	disease	0,72	disease	0,84	7	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,87	low_impact	-3,55	medium_impact	0,54	medium_impact	1,55	0,92	0,95	50,88	8,57	N	0,31	N	0,93	NA	NA	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14170	14170	A	T	MI.23143	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	504	168	I	M	atT/atA	1,54	0,06	0	probably_damaging	1	neutral	0,23	neutral	1,99	neutral	-1,12	neutral	-0,8	low_impact	1,24	neutral	0,87	neutral	0,92	neutral	1,52	13,43	0,47	0,55	neutral	0,18	neutral	0,4	neutral	0,26	neutral	0,45	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,67	low_impact	-3,55	medium_impact	-0,09	medium_impact	-0,1	0,91	0,95	48,23	8,83	N	0,45	N	0,17	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14170	14170	A	C	MI.23144	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	504	168	I	M	atT/atG	1,54	0,06	0	probably_damaging	1	neutral	0,23	neutral	1,99	neutral	-1,12	neutral	-0,8	low_impact	1,24	neutral	0,87	neutral	0,92	neutral	1,38	12,68	0,47	0,55	neutral	0,18	neutral	0,4	neutral	0,26	neutral	0,45	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,67	low_impact	-3,55	medium_impact	-0,09	medium_impact	-0,1	0,91	0,95	48,23	8,83	N	0,43	N	0,17	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14171	14171	A	G	MI.23145	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	503	168	I	T	aTt/aCt	-4,87	0	0	probably_damaging	1	neutral	0,46	neutral	2,02	neutral	-2,87	deleterious	-3,77	medium_impact	2,69	neutral	0,84	neutral	0,4	deleterious	3,7	23,3	0,54	0,6	disease	0,53	disease	0,63	disease	0,51	disease	0,59	2	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,78	low_impact	-3,55	medium_impact	0,17	medium_impact	1,11	0,79	0,85	48,23	8,83	N	0,25	N	0,91	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14171	14171	A	C	MI.23146	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	503	168	I	S	aTt/aGt	-4,87	0	0	probably_damaging	1	neutral	0,48	neutral	2,03	deleterious	-3,5	deleterious	-4,59	medium_impact	2,69	neutral	0,75	damaging	0,24	deleterious	4,14	23,8	0,37	0,5	disease	0,65	disease	0,83	disease	0,52	disease	0,78	6	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,83	low_impact	-3,55	medium_impact	0,19	medium_impact	1,11	0,61	0,8	48,23	8,83	N	0,25	N	0,88	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14171	14171	A	T	MI.23147	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	503	168	I	N	aTt/aAt	-4,87	0	0	probably_damaging	1	neutral	0,36	neutral	1,97	deleterious	-4,54	deleterious	-5,59	medium_impact	3,04	neutral	0,72	damaging	0,2	deleterious	4,46	24,2	0,4	0,5	disease	0,78	disease	0,87	disease	0,55	disease	0,79	6	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,86	low_impact	-3,55	medium_impact	0,07	medium_impact	1,41	0,64	0,8	48,23	8,83	N	0,25	N	0,9	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14172	14172	T	C	MI.23148	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	502	168	I	V	Att/Gtt	4,52	0,56	0	probably_damaging	1	neutral	0,53	neutral	2,16	neutral	-0,92	neutral	-0,76	medium_impact	2	neutral	0,82	neutral	0,49	deleterious	1,91	15,67	0,55	0,6	neutral	0,22	neutral	0,5	neutral	0,43	disease	0,51	0	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,68	low_impact	-3,55	medium_impact	0,24	medium_impact	0,54	0,77	0,85	48,23	8,83	N	0,33	N	0,59	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14172	14172	T	G	MI.23149	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	502	168	I	L	Att/Ctt	4,52	0,56	0	probably_damaging	1	neutral	0,69	neutral	2,28	neutral	1,75	neutral	-0,38	neutral_impact	0,44	neutral	0,88	neutral	0,88	deleterious	2,49	19,4	0,44	0,55	neutral	0,09	neutral	0,19	neutral	0,29	neutral	0,31	4	deleterious	0,99	neutral	0,35	neutral	-2	deleterious	0,64	low_impact	-3,55	medium_impact	0,4	medium_impact	-0,77	0,84	0,9	48,23	8,83	N	0,37	N	0,33	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6107	6107	C	A	MI.2315	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	204	68	F	L	ttC/ttA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,84	neutral	-2,72	deleterious	-3,87	medium_impact	3,06	damaging	0,57	damaging	0,18	deleterious	4,59	24,4	0,34	0,55	neutral	0,26	disease	0,81	disease	0,59	disease	0,69	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	medium_impact	1,73	0,68	0,9	3,9	6,74	N	0,48	N	0,83	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14172	14172	T	A	MI.23150	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	502	168	I	F	Att/Ttt	4,52	0,56	0	probably_damaging	1	neutral	0,71	neutral	1,97	neutral	-1,77	deleterious	-2,86	medium_impact	2,5	neutral	0,77	neutral	0,33	deleterious	4,29	24	0,37	0,5	neutral	0,41	disease	0,81	neutral	0,46	disease	0,74	5	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,8	low_impact	-3,55	medium_impact	0,42	medium_impact	0,95	0,86	0,9	48,23	8,83	N	0,25	N	0,75	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14174	14174	A	C	MI.23151	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	500	167	V	G	gTa/gGa	-8,54	0	0	possibly_damaging	0,67	neutral	0,34	neutral	2,03	deleterious	-5,58	deleterious	-6,15	high_impact	3,56	neutral	0,6	neutral	0,51	deleterious	3,64	23,2	0,18	0,45	neutral	0,38	disease	0,91	disease	0,7	disease	0,8	6	neutral	0,73	neutral	0,34	deleterious	1	deleterious	0,68	low_impact	-1,08	medium_impact	0,05	medium_impact	1,84	0,62	0,8	49,12	8,62	N	0,41	N	0,88	NA	NA	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14174	14174	A	G	MI.23152	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	500	167	V	A	gTa/gCa	-8,54	0	0	benign	0,05	neutral	0,51	neutral	2,21	deleterious	-3,65	deleterious	-3,09	low_impact	1,73	neutral	0,92	neutral	0,86	deleterious	2,61	20,3	0,33	0,5	neutral	0,39	disease	0,79	disease	0,57	disease	0,58	2	neutral	0,44	deleterious	0,73	neutral	-6	neutral	0,28	medium_impact	0,38	medium_impact	0,22	medium_impact	0,31	0,72	0,85	49,12	8,62	N	0,31	N	0,41	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14174	14174	A	T	MI.23153	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	500	167	V	E	gTa/gAa	-8,54	0	0	possibly_damaging	0,87	neutral	0,28	neutral	2	deleterious	-5,42	deleterious	-5,34	high_impact	3,56	neutral	0,6	neutral	0,42	deleterious	4,43	24,2	0,13	0,4	disease	0,67	disease	0,95	disease	0,77	disease	0,9	8	neutral	0,9	neutral	0,21	deleterious	1	deleterious	0,85	low_impact	-1,55	medium_impact	-0,02	medium_impact	1,84	0,71	0,85	49,12	8,62	N	0,42	N	0,9	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14175	14175	C	T	MI.23154	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	499	167	V	M	Gta/Ata	3,15	0,04	0	probably_damaging	0,97	neutral	0,22	neutral	2,06	deleterious	-4,32	neutral	-2,35	high_impact	3,56	neutral	0,62	neutral	0,48	deleterious	4,11	23,7	0,37	0,5	disease	0,51	disease	0,83	disease	0,71	disease	0,76	5	neutral	0,98	neutral	0,13	deleterious	2	deleterious	0,77	low_impact	-2,18	medium_impact	-0,1	medium_impact	1,84	0,9	0,95	49,12	8,62	N	0,42	N	0,59	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14175	14175	C	G	MI.23155	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	499	167	V	L	Gta/Cta	3,15	0,04	0	possibly_damaging	0,56	neutral	0,65	neutral	2,08	neutral	-2,44	neutral	-1,96	high_impact	3,56	damaging	0,59	neutral	0,47	deleterious	3,95	23,6	0,33	0,5	neutral	0,28	disease	0,88	disease	0,67	disease	0,76	5	neutral	0,48	deleterious	0,55	deleterious	1	deleterious	0,65	medium_impact	-0,89	medium_impact	0,36	medium_impact	1,84	0,77	0,85	49,12	8,62	N	0,4	N	0,63	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14175	14175	C	A	MI.23156	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	499	167	V	L	Gta/Tta	3,15	0,04	0	possibly_damaging	0,56	neutral	0,65	neutral	2,08	neutral	-2,44	neutral	-1,96	high_impact	3,56	damaging	0,59	neutral	0,47	deleterious	4,24	23,9	0,33	0,5	neutral	0,28	disease	0,88	disease	0,67	disease	0,76	5	neutral	0,48	deleterious	0,55	deleterious	1	deleterious	0,65	medium_impact	-0,89	medium_impact	0,36	medium_impact	1,84	0,77	0,85	49,12	8,62	N	0,38	N	0,63	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14176	14176	A	T	MI.23157	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	498	166	I	M	atT/atA	0,63	0	0	possibly_damaging	0,86	neutral	0,23	neutral	2,22	deleterious	-3,42	deleterious	-2,7	medium_impact	3,19	neutral	0,7	neutral	0,48	deleterious	3,09	22,5	0,47	0,55	neutral	0,49	disease	0,78	disease	0,63	disease	0,77	5	neutral	0,9	neutral	0,19	NA	0	deleterious	0,71	low_impact	-1,52	medium_impact	-0,09	medium_impact	1,53	0,88	0,9	49,56	8,89	N	0,37	N	0,76	NA	NA	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14176	14176	A	C	MI.23158	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	498	166	I	M	atT/atG	0,63	0	0	possibly_damaging	0,86	neutral	0,23	neutral	2,22	deleterious	-3,42	deleterious	-2,7	medium_impact	3,19	neutral	0,7	neutral	0,48	deleterious	3,02	22,3	0,47	0,55	neutral	0,49	disease	0,78	disease	0,63	disease	0,77	5	neutral	0,9	neutral	0,19	NA	0	deleterious	0,71	low_impact	-1,52	medium_impact	-0,09	medium_impact	1,53	0,88	0,9	49,56	8,89	N	0,36	N	0,76	NA	NA	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14177	14177	A	G	MI.23159	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	497	166	I	T	aTt/aCt	-3,04	0	0	possibly_damaging	0,58	neutral	0,45	neutral	2,25	deleterious	-3,37	deleterious	-4,4	medium_impact	3,19	neutral	0,75	neutral	0,69	deleterious	2,12	16,97	0,53	0,6	neutral	0,46	disease	0,82	disease	0,55	disease	0,74	5	neutral	0,59	neutral	0,44	NA	0	deleterious	0,57	medium_impact	-0,92	medium_impact	0,16	medium_impact	1,53	0,8	0,85	49,56	8,89	N	0,4	N	0,78	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6108	6108	A	G	MI.2316	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	205	69	M	V	Ata/Gta	-2,65	0	0	benign	0,08	deleterious	0	neutral	2,93	neutral	1,32	neutral	-2,19	medium_impact	2,72	damaging	0,58	damaging	0,09	deleterious	0,79	9,4	0,53	0,6	neutral	0,19	disease	0,9	neutral	0,47	disease	0,53	1	deleterious	1	neutral	0,46	deleterious	1	neutral	0,26	medium_impact	0,24	low_impact	-1,48	medium_impact	1,41	0,49	0,9	7,02	12,6	N	0,28	N	0,73	disease_causing	0,76	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14177	14177	A	C	MI.23160	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	497	166	I	S	aTt/aGt	-3,04	0	0	possibly_damaging	0,81	neutral	0,51	neutral	2,31	deleterious	-4,16	deleterious	-5,69	medium_impact	2,85	neutral	0,73	neutral	0,55	deleterious	3,95	23,6	0,34	0,5	disease	0,59	disease	0,92	disease	0,61	disease	0,81	6	neutral	0,79	neutral	0,35	NA	0	deleterious	0,76	low_impact	-1,37	medium_impact	0,22	medium_impact	1,25	0,69	0,85	49,56	8,89	N	0,3	N	0,85	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14177	14177	A	T	MI.23161	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	497	166	I	N	aTt/aAt	-3,04	0	0	probably_damaging	0,92	neutral	0,37	neutral	2,19	deleterious	-5,21	deleterious	-6,69	medium_impact	3,19	neutral	0,72	neutral	0,51	deleterious	4,3	24	0,35	0,5	disease	0,74	disease	0,95	disease	0,63	disease	0,84	7	neutral	0,93	neutral	0,23	deleterious	1	deleterious	0,83	low_impact	-1,77	medium_impact	0,08	medium_impact	1,53	0,74	0,85	49,56	8,89	N	0,29	N	0,95	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14178	14178	T	A	MI.23162	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	496	166	I	F	Att/Ttt	3,61	0,1	0,02	possibly_damaging	0,81	neutral	0,71	neutral	2,25	deleterious	-3,73	deleterious	-3,99	medium_impact	3,19	neutral	0,75	neutral	0,54	deleterious	4,12	23,8	0,38	0,5	disease	0,54	disease	0,92	disease	0,64	disease	0,82	6	neutral	0,78	neutral	0,45	NA	0	deleterious	0,74	low_impact	-1,37	medium_impact	0,42	medium_impact	1,53	0,87	0,9	49,56	8,89	N	0,29	N	0,87	NA	NA	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14178	14178	T	G	MI.23163	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	496	166	I	L	Att/Ctt	3,61	0,1	0,02	benign	0,23	neutral	0,69	neutral	2,3	neutral	-1,41	neutral	-1,99	medium_impact	2,85	neutral	0,85	neutral	0,56	deleterious	2,28	18,05	0,36	0,5	neutral	0,24	disease	0,81	disease	0,59	disease	0,78	6	neutral	0,2	deleterious	0,73	neutral	-3	neutral	0,31	medium_impact	-0,32	medium_impact	0,4	medium_impact	1,25	0,82	0,85	49,56	8,89	N	0,36	N	0,66	NA	NA	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14178	14178	T	C	MI.23164	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	496	166	I	V	Att/Gtt	3,61	0,1	0,02	benign	0,02	neutral	0,54	neutral	2,34	neutral	0,95	neutral	-0,42	neutral_impact	0,22	neutral	0,97	neutral	0,99	neutral	-0,8	0,04	0,49	0,55	neutral	0,1	neutral	0,15	neutral	0,37	neutral	0,23	5	neutral	0,43	deleterious	0,76	neutral	-6	neutral	0,1	medium_impact	0,75	medium_impact	0,25	medium_impact	-0,96	0,77	0,85	49,56	8,89	N	0,43	N	0	NA	NA	0,2	rs28357671	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14180	14180	T	C	MI.23165	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	494	165	Y	C	tAt/tGt	-0,52	0	0,03	probably_damaging	0,96	neutral	0,18	neutral	2,3	deleterious	-6,77	deleterious	-2,55	low_impact	1,9	neutral	0,96	neutral	0,43	deleterious	3,45	23	0,4	0,5	neutral	0,38	disease	0,91	disease	0,56	disease	0,81	6	neutral	0,97	neutral	0,11	neutral	-2	deleterious	0,78	low_impact	-2,06	medium_impact	-0,16	medium_impact	0,45	0,38	0,8	48,67	8,72	N	0,38	N	0,67	NA	NA	0,57	rs200933339	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14180	14180	T	A	MI.23166	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	494	165	Y	F	tAt/tTt	-0,52	0	0,03	possibly_damaging	0,65	neutral	0,71	neutral	2,42	neutral	-2,93	neutral	1,25	neutral_impact	-0,68	neutral	0,88	neutral	0,95	neutral	1,01	10,74	0,4	0,5	neutral	0,09	neutral	0,24	neutral	0,39	neutral	0,39	2	neutral	0,58	deleterious	0,53	neutral	-3	deleterious	0,52	low_impact	-1,04	medium_impact	0,42	low_impact	-1,71	0,65	0,8	48,67	8,72	N	0,25	N	0,27	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14180	14180	T	G	MI.23167	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	494	165	Y	S	tAt/tCt	-0,52	0	0,03	possibly_damaging	0,7	neutral	0,44	neutral	2,32	deleterious	-4,84	deleterious	-2,98	medium_impact	2,24	neutral	0,84	neutral	0,6	deleterious	4,05	23,7	0,34	0,5	neutral	0,25	disease	0,86	disease	0,58	disease	0,81	6	neutral	0,7	neutral	0,37	NA	0	deleterious	0,61	low_impact	-1,13	medium_impact	0,15	medium_impact	0,74	0,5	0,8	48,67	8,72	N	0,29	N	0,75	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14181	14181	A	G	MI.23168	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	493	165	Y	H	Tat/Cat	2,92	0,35	0	benign	0,02	neutral	0,54	neutral	2,3	deleterious	-5,03	deleterious	-2,64	neutral_impact	0,63	neutral	0,86	neutral	0,49	deleterious	0,7	8,86	0,36	0,5	neutral	0,41	disease	0,78	disease	0,6	disease	0,74	5	neutral	0,44	deleterious	0,76	neutral	-6	neutral	0,25	medium_impact	0,75	medium_impact	0,25	medium_impact	-0,61	0,62	0,8	48,67	8,72	N	0,33	N	0,63	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14181	14181	A	C	MI.23169	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	493	165	Y	D	Tat/Gat	2,92	0,35	0	possibly_damaging	0,76	neutral	0,22	neutral	2,29	deleterious	-5,53	deleterious	-4,16	medium_impact	2,24	neutral	0,8	neutral	0,37	deleterious	3,62	23,2	0,24	0,45	disease	0,53	disease	0,93	disease	0,67	disease	0,83	7	neutral	0,85	neutral	0,23	NA	0	deleterious	0,77	low_impact	-1,26	medium_impact	-0,1	medium_impact	0,74	0,54	0,8	48,67	8,72	N	0,29	N	0,81	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6108	6108	A	T	MI.2317	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	205	69	M	L	Ata/Tta	-2,65	0	0	benign	0,05	neutral	0,07	neutral	2,94	neutral	1,39	neutral	-1,58	low_impact	1,84	damaging	0,59	damaging	0,1	deleterious	0,21	4,74	0,46	0,55	neutral	0,24	disease	0,77	neutral	0,43	disease	0,52	0	neutral	0,93	deleterious	0,51	neutral	-6	neutral	0,25	medium_impact	0,45	medium_impact	-0,43	medium_impact	0,6	0,54	0,9	7,02	12,6	N	0,31	N	0,43	disease_causing	0,72	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14181	14181	A	T	MI.23170	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	493	165	Y	N	Tat/Aat	2,92	0,35	0	possibly_damaging	0,63	neutral	0,34	neutral	2,3	deleterious	-5,32	deleterious	-3,85	medium_impact	2,24	neutral	0,8	neutral	0,53	deleterious	3,58	23,2	0,34	0,5	neutral	0,4	disease	0,9	disease	0,59	disease	0,81	6	neutral	0,7	neutral	0,36	NA	0	deleterious	0,63	low_impact	-1,01	medium_impact	0,05	medium_impact	0,74	0,5	0,8	48,67	8,72	N	0,31	N	0,75	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14183	14183	A	C	MI.23171	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	491	164	V	G	gTa/gGa	-3,5	0	0	possibly_damaging	0,82	neutral	0,67	neutral	2,19	deleterious	-3,2	deleterious	-6,88	medium_impact	2,96	neutral	0,86	neutral	0,56	deleterious	3,57	23,1	0,18	0,45	disease	0,71	disease	0,89	disease	0,65	disease	0,81	6	neutral	0,79	neutral	0,43	NA	0	deleterious	0,81	low_impact	-1,4	medium_impact	0,38	medium_impact	1,34	0,61	0,8	48,67	8,91	N	0,22	N	0,94	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14183	14183	A	T	MI.23172	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	491	164	V	E	gTa/gAa	-3,5	0	0	probably_damaging	0,91	neutral	0,7	neutral	2,19	deleterious	-3,43	deleterious	-5,88	medium_impact	2,96	neutral	0,79	neutral	0,44	deleterious	4,33	24	0,13	0,4	disease	0,71	disease	0,95	disease	0,75	disease	0,91	8	neutral	0,89	neutral	0,4	deleterious	1	deleterious	0,86	low_impact	-1,72	medium_impact	0,41	medium_impact	1,34	0,73	0,85	48,67	8,91	N	0,22	N	0,94	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14183	14183	A	G	MI.23173	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	491	164	V	A	gTa/gCa	-3,5	0	0	possibly_damaging	0,46	neutral	0,83	neutral	2,24	neutral	-1,28	deleterious	-3,92	medium_impact	2,96	neutral	0,77	neutral	0,59	deleterious	3,36	22,9	0,31	0,45	neutral	0,42	disease	0,77	disease	0,64	disease	0,77	5	neutral	0,35	deleterious	0,69	NA	0	deleterious	0,61	medium_impact	-0,73	medium_impact	0,59	medium_impact	1,34	0,48	0,8	48,67	8,91	N	0,23	N	0,79	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14184	14184	C	A	MI.23174	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	490	164	V	L	Gta/Tta	7,04	0,69	0	benign	0,14	neutral	0,84	neutral	2,8	neutral	2,37	neutral	-2,21	neutral_impact	0,44	neutral	0,78	neutral	0,69	deleterious	2,38	18,69	0,32	0,5	neutral	0,11	neutral	0,27	neutral	0,37	neutral	0,43	2	neutral	0,07	deleterious	0,85	neutral	-6	neutral	0,24	medium_impact	-0,07	medium_impact	0,61	medium_impact	-0,77	0,68	0,85	48,67	8,91	N	0,43	N	0,67	NA	NA	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14184	14184	C	G	MI.23175	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	490	164	V	L	Gta/Cta	7,04	0,69	0	benign	0,14	neutral	0,84	neutral	2,8	neutral	2,37	neutral	-2,21	neutral_impact	0,44	neutral	0,78	neutral	0,69	deleterious	2,09	16,81	0,32	0,5	neutral	0,11	neutral	0,27	neutral	0,37	neutral	0,43	2	neutral	0,07	deleterious	0,85	neutral	-6	neutral	0,24	medium_impact	-0,07	medium_impact	0,61	medium_impact	-0,77	0,68	0,85	48,67	8,91	N	0,44	N	0,67	NA	NA	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14184	14184	C	T	MI.23176	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	490	164	V	M	Gta/Ata	7,04	0,69	0	benign	0,12	neutral	0,28	neutral	2,52	neutral	1,36	neutral	-2,43	low_impact	1,26	neutral	0,87	neutral	0,54	neutral	1,22	11,85	0,37	0,5	neutral	0,4	disease	0,72	disease	0,54	disease	0,64	3	neutral	0,68	deleterious	0,58	neutral	-6	neutral	0,28	medium_impact	0	medium_impact	-0,02	medium_impact	-0,08	0,72	0,85	48,67	8,91	N	0,45	N	0,61	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14186	14186	C	A	MI.23177	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	488	163	G	V	gGt/gTt	-0,98	0	0	probably_damaging	1	neutral	0,56	neutral	2,67	deleterious	-5,73	deleterious	-5,8	low_impact	1,88	neutral	0,74	neutral	0,67	deleterious	4,37	24,1	0,37	0,5	neutral	0,46	disease	0,9	disease	0,58	disease	0,79	6	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,85	low_impact	-3,55	medium_impact	0,27	medium_impact	0,44	0,77	0,85	49,56	8,85	N	0,26	N	0,98	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14186	14186	C	T	MI.23178	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	488	163	G	D	gGt/gAt	-0,98	0	0	probably_damaging	1	neutral	0,33	neutral	2,25	deleterious	-5,45	deleterious	-4,16	medium_impact	3,08	neutral	0,75	neutral	0,42	deleterious	4,23	23,9	0,2	0,45	neutral	0,45	disease	0,92	disease	0,69	disease	0,83	7	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,87	low_impact	-3,55	medium_impact	0,04	medium_impact	1,44	0,74	0,85	49,56	8,85	N	0,36	N	0,96	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14186	14186	C	G	MI.23179	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	488	163	G	A	gGt/gCt	-0,98	0	0	probably_damaging	1	neutral	0,66	neutral	2,54	deleterious	-4,4	deleterious	-2,96	low_impact	1,43	neutral	0,81	neutral	0,77	deleterious	2,33	18,35	0,5	0,6	neutral	0,19	disease	0,71	neutral	0,32	disease	0,55	1	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,75	low_impact	-3,55	medium_impact	0,37	medium_impact	0,06	0,83	0,85	49,56	8,85	N	0,24	N	0,75	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6108	6108	A	C	MI.2318	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	205	69	M	L	Ata/Cta	-2,65	0	0	benign	0,05	neutral	0,07	neutral	2,94	neutral	1,39	neutral	-1,58	low_impact	1,84	damaging	0,59	damaging	0,1	deleterious	0,14	4,03	0,46	0,55	neutral	0,24	disease	0,77	neutral	0,43	disease	0,52	0	neutral	0,93	deleterious	0,51	neutral	-6	neutral	0,25	medium_impact	0,45	medium_impact	-0,43	medium_impact	0,6	0,54	0,9	7,02	12,6	N	0,31	N	0,43	disease_causing	0,72	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14187	14187	C	T	MI.23180	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	487	163	G	S	Ggt/Agt	1,31	0	0	probably_damaging	1	neutral	0,55	neutral	2,33	deleterious	-4,66	neutral	-2,12	low_impact	1,28	neutral	0,87	neutral	0,95	deleterious	2,55	19,82	0,41	0,5	neutral	0,29	disease	0,68	neutral	0,32	disease	0,52	0	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,76	low_impact	-3,55	medium_impact	0,26	medium_impact	-0,07	0,93	0,95	49,56	8,85	N	0,28	N	0,81	NA	NA	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14187	14187	C	G	MI.23181	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	487	163	G	R	Ggt/Cgt	1,31	0	0	probably_damaging	1	neutral	0,49	neutral	2,26	deleterious	-5,95	deleterious	-5,04	medium_impact	3,08	neutral	0,71	neutral	0,41	deleterious	4,21	23,9	0,26	0,45	neutral	0,49	disease	0,93	disease	0,71	disease	0,86	7	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,88	low_impact	-3,55	medium_impact	0,2	medium_impact	1,44	0,79	0,85	49,56	8,85	N	0,29	N	0,96	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14187	14187	C	A	MI.23182	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	487	163	G	C	Ggt/Tgt	1,31	0	0	probably_damaging	1	neutral	0,19	neutral	2,29	deleterious	-7,01	deleterious	-5,13	medium_impact	1,98	neutral	0,86	neutral	0,81	deleterious	3,52	23,1	0,28	0,45	disease	0,68	disease	0,89	neutral	0,39	disease	0,63	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,88	low_impact	-3,55	medium_impact	-0,14	medium_impact	0,52	0,77	0,85	49,56	8,85	N	0,36	N	0,9	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14189	14189	A	C	MI.23183	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	485	162	V	G	gTt/gGt	-0,52	0	0	possibly_damaging	0,83	neutral	0,34	neutral	2,07	deleterious	-5,02	deleterious	-5,91	medium_impact	2,88	neutral	0,76	neutral	0,47	deleterious	3,57	23,1	0,19	0,45	disease	0,66	disease	0,85	disease	0,66	disease	0,82	6	neutral	0,85	neutral	0,26	NA	0	deleterious	0,73	low_impact	-1,43	medium_impact	0,05	medium_impact	1,27	0,64	0,8	49,56	8,89	N	0,28	N	0,86	NA	NA	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14189	14189	A	G	MI.23184	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	485	162	V	A	gTt/gCt	-0,52	0	0	possibly_damaging	0,47	neutral	0,52	neutral	2,17	deleterious	-3,61	deleterious	-2,95	low_impact	1,9	neutral	0,84	neutral	0,86	deleterious	0,67	8,62	0,37	0,5	neutral	0,22	disease	0,7	disease	0,62	disease	0,74	5	neutral	0,46	deleterious	0,53	neutral	-3	deleterious	0,49	medium_impact	-0,75	medium_impact	0,23	medium_impact	0,45	0,48	0,8	49,56	8,89	N	0,25	N	0,38	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14189	14189	A	T	MI.23185	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	485	162	V	D	gTt/gAt	-0,52	0	0	possibly_damaging	0,88	neutral	0,21	neutral	2,05	deleterious	-5,67	deleterious	-5,71	medium_impact	2,88	neutral	0,77	neutral	0,43	deleterious	4,38	24,1	0,11	0,4	disease	0,76	disease	0,91	disease	0,76	disease	0,85	7	neutral	0,93	neutral	0,17	NA	0	deleterious	0,82	low_impact	-1,59	medium_impact	-0,11	medium_impact	1,27	0,65	0,8	49,56	8,89	N	0,31	N	0,89	NA	NA	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14190	14190	C	G	MI.23186	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	484	162	V	L	Gtt/Ctt	2,69	0,01	0	benign	0,24	neutral	0,67	neutral	2,31	neutral	-2,68	neutral	-1,54	neutral_impact	0,42	neutral	0,79	neutral	0,73	deleterious	2,55	19,77	0,35	0,5	neutral	0,11	neutral	0,24	neutral	0,28	neutral	0,42	2	neutral	0,22	deleterious	0,72	neutral	-6	neutral	0,31	medium_impact	-0,34	medium_impact	0,38	medium_impact	-0,79	0,7	0,85	49,56	8,89	N	0,32	N	0,6	NA	NA	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14190	14190	C	A	MI.23187	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	484	162	V	F	Gtt/Ttt	2,69	0,01	0	possibly_damaging	0,85	neutral	0,71	neutral	2,13	deleterious	-4,72	deleterious	-3,44	medium_impact	2,19	neutral	0,87	neutral	0,68	deleterious	3,3	22,9	0,19	0,45	neutral	0,46	disease	0,9	disease	0,58	disease	0,79	6	neutral	0,82	neutral	0,43	NA	0	deleterious	0,77	low_impact	-1,49	medium_impact	0,42	medium_impact	0,7	0,77	0,85	49,56	8,89	N	0,28	N	0,79	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14190	14190	C	T	MI.23188	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	484	162	V	I	Gtt/Att	2,69	0,01	0	possibly_damaging	0,47	neutral	0,4	neutral	2,47	neutral	-2,26	neutral	-0,13	low_impact	0,88	neutral	0,84	neutral	0,98	neutral	1,55	13,58	0,43	0,55	neutral	0,1	neutral	0,33	neutral	0,34	neutral	0,43	1	neutral	0,57	neutral	0,47	neutral	-3	neutral	0,42	medium_impact	-0,75	medium_impact	0,11	medium_impact	-0,4	0,77	0,85	49,56	8,89	N	0,41	N	0,09	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14191	14191	A	T	MI.23189	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	483	161	F	L	ttT/ttA	-0,75	0	0	benign	0,04	neutral	1	neutral	2,7	neutral	-2,75	deleterious	-3,92	neutral_impact	0,57	neutral	0,91	neutral	0,98	deleterious	0,73	9	0,35	0,5	neutral	0,14	neutral	0,35	neutral	0,41	neutral	0,44	1	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,14	medium_impact	0,47	high_impact	1,87	medium_impact	-0,66	0,51	0,8	50,44	8,87	N	0,34	N	0,39	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6109	6109	T	C	MI.2319	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	206	69	M	T	aTa/aCa	7,07	1	0	benign	0,01	deleterious	0	neutral	2,78	neutral	-0,65	deleterious	-3,54	medium_impact	2,79	neutral	0,6	damaging	0,14	neutral	0,93	10,24	0,48	0,55	neutral	0,42	disease	0,89	disease	0,58	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	1	neutral	0,32	medium_impact	1,12	low_impact	-1,48	medium_impact	1,48	0,45	0,9	7,02	12,6	N	0,47	N	0,13	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14191	14191	A	C	MI.23190	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	483	161	F	L	ttT/ttG	-0,75	0	0	benign	0,04	neutral	1	neutral	2,7	neutral	-2,75	deleterious	-3,92	neutral_impact	0,57	neutral	0,91	neutral	0,98	deleterious	0,65	8,48	0,35	0,5	neutral	0,14	neutral	0,35	neutral	0,41	neutral	0,44	1	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,14	medium_impact	0,47	high_impact	1,87	medium_impact	-0,66	0,51	0,8	50,44	8,87	N	0,35	N	0,39	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14192	14192	A	T	MI.23191	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	482	161	F	Y	tTt/tAt	-0,29	0	0	possibly_damaging	0,78	neutral	0,98	neutral	2,21	deleterious	-3,12	deleterious	-2,58	medium_impact	2,74	neutral	0,74	neutral	0,58	deleterious	3,86	23,5	0,21	0,45	neutral	0,48	disease	0,87	disease	0,69	disease	0,8	6	neutral	0,77	deleterious	0,6	NA	0	deleterious	0,73	low_impact	-1,3	medium_impact	1,15	medium_impact	1,16	0,61	0,8	50,44	8,87	N	0,25	N	0,75	NA	NA	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14192	14192	A	C	MI.23192	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	482	161	F	C	tTt/tGt	-0,29	0	0	probably_damaging	0,97	neutral	0,18	neutral	2,19	deleterious	-6,52	deleterious	-6,53	medium_impact	3,44	neutral	0,74	neutral	0,46	deleterious	3,84	23,4	0,25	0,45	disease	0,69	disease	0,92	disease	0,7	disease	0,82	6	neutral	0,98	neutral	0,11	deleterious	1	deleterious	0,84	low_impact	-2,18	medium_impact	-0,16	medium_impact	1,74	0,42	0,8	50,44	8,87	N	0,35	N	0,88	NA	NA	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14192	14192	A	G	MI.23193	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	482	161	F	S	tTt/tCt	-0,29	0	0	probably_damaging	0,91	neutral	0,5	neutral	2,21	deleterious	-4,91	deleterious	-6,73	medium_impact	3,44	neutral	0,75	neutral	0,54	deleterious	4,46	24,2	0,27	0,45	disease	0,57	disease	0,9	disease	0,68	disease	0,8	6	neutral	0,9	neutral	0,3	deleterious	1	deleterious	0,79	low_impact	-1,72	medium_impact	0,21	medium_impact	1,74	0,51	0,8	50,44	8,87	N	0,32	N	0,96	NA	NA	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14193	14193	A	C	MI.23194	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	481	161	F	V	Ttt/Gtt	6,59	0,79	0	possibly_damaging	0,57	neutral	0,59	neutral	2,32	deleterious	-3,78	deleterious	-5,32	medium_impact	2,4	neutral	0,84	neutral	0,85	neutral	1,16	11,53	0,31	0,45	neutral	0,22	disease	0,92	disease	0,64	disease	0,61	2	neutral	0,51	deleterious	0,51	NA	0	deleterious	0,56	medium_impact	-0,91	medium_impact	0,29	medium_impact	0,87	0,62	0,8	50,44	8,87	N	0,38	N	0,91	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14193	14193	A	T	MI.23195	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	481	161	F	I	Ttt/Att	6,59	0,79	0	possibly_damaging	0,44	neutral	0,45	neutral	2,3	deleterious	-3,78	deleterious	-4,32	medium_impact	2,75	neutral	0,74	neutral	0,54	deleterious	2,41	18,87	0,25	0,45	neutral	0,14	disease	0,86	disease	0,62	disease	0,75	5	neutral	0,51	deleterious	0,51	NA	0	deleterious	0,5	medium_impact	-0,7	medium_impact	0,16	medium_impact	1,16	0,64	0,8	50,44	8,87	N	0,39	N	0,81	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14193	14193	A	G	MI.23196	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	481	161	F	L	Ttt/Ctt	6,59	0,79	0	benign	0,04	neutral	1	neutral	2,7	neutral	-2,75	deleterious	-3,92	neutral_impact	0,57	neutral	0,91	neutral	0,98	neutral	1,06	11	0,35	0,5	neutral	0,14	neutral	0,35	neutral	0,41	neutral	0,44	1	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,14	medium_impact	0,47	high_impact	1,87	medium_impact	-0,66	0,51	0,8	50,44	8,87	N	0,51	P	0,39	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14194	14194	C	A	MI.23197	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	480	160	L	F	ttG/ttT	-0,06	0	0	probably_damaging	1	neutral	0,71	neutral	0,41	deleterious	-6,98	deleterious	-3,92	high_impact	3,94	neutral	0,62	damaging	0,07	deleterious	4,3	24	0,32	0,5	disease	0,54	disease	0,91	disease	0,76	disease	0,82	6	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	0,42	high_impact	2,16	0,63	0,8	50	8,83	N	0,37	N	0,8	NA	NA	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14194	14194	C	G	MI.23198	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	480	160	L	F	ttG/ttC	-0,06	0	0	probably_damaging	1	neutral	0,71	neutral	0,41	deleterious	-6,98	deleterious	-3,92	high_impact	3,94	neutral	0,62	damaging	0,07	deleterious	3,84	23,4	0,32	0,5	disease	0,54	disease	0,91	disease	0,76	disease	0,82	6	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	0,42	high_impact	2,16	0,63	0,8	50	8,83	N	0,32	N	0,8	NA	NA	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14195	14195	A	C	MI.23199	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	479	160	L	W	tTg/tGg	-4,87	0	0	probably_damaging	1	neutral	0,19	neutral	0,38	deleterious	-10,42	deleterious	-5,88	high_impact	3,94	damaging	0,5	damaging	0,04	deleterious	3,45	23	0,13	0,4	disease	0,9	disease	0,94	disease	0,78	disease	0,9	8	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,14	high_impact	2,16	0,58	0,8	50	8,83	N	0,34	N	0,91	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8635	8635	C	A	MI.232	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	109	37	L	I	Ctc/Atc	-1,26	0	0	benign	0,39	neutral	0,27	neutral	4,33	neutral	-0,7	neutral	-1,42	low_impact	1,01	neutral	0,91	neutral	0,63	deleterious	2,31	18,22	0,39	0,65	neutral	0,49	neutral	0,32	disease	0,51	neutral	0,46	1	neutral	0,68	neutral	0,44	neutral	-6	neutral	0,41	medium_impact	-0,57	medium_impact	0,05	medium_impact	-0,23	0,66	0,9	20,35	20,89	N	0,41	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6109	6109	T	A	MI.2320	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	206	69	M	K	aTa/aAa	7,07	1	0	benign	0,17	deleterious	0	neutral	2,74	neutral	-1,97	deleterious	-3,67	high_impact	4,67	damaging	0,57	damaging	0,05	deleterious	2,08	16,71	0,25	0,55	disease	0,61	disease	0,95	disease	0,7	disease	0,87	7	deleterious	1	neutral	0,42	deleterious	2	neutral	0,43	medium_impact	-0,11	low_impact	-1,48	high_impact	3,21	0,53	0,9	7,02	12,6	P	0,56	P	0,8	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14195	14195	A	G	MI.23200	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	479	160	L	S	tTg/tCg	-4,87	0	0	probably_damaging	1	neutral	0,66	neutral	0,39	deleterious	-7,79	deleterious	-5,88	high_impact	3,6	damaging	0,47	damaging	0,04	deleterious	3,82	23,4	0,18	0,45	disease	0,8	disease	0,93	disease	0,76	disease	0,87	7	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	0,37	medium_impact	1,88	0,55	0,8	50	8,83	N	0,38	N	0,91	NA	NA	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14196	14196	A	C	MI.23201	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	478	160	L	V	Ttg/Gtg	8,42	0,92	0	probably_damaging	1	neutral	0,61	neutral	0,42	deleterious	-6,46	deleterious	-2,92	high_impact	3,94	damaging	0,4	damaging	0,04	deleterious	3,4	23	0,28	0,45	neutral	0,38	disease	0,89	disease	0,76	disease	0,8	6	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,81	low_impact	-3,55	medium_impact	0,31	high_impact	2,16	0,71	0,85	50	8,83	P	0,67	P	0,6	NA	NA	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14196	14196	A	T	MI.23202	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	478	160	L	M	Ttg/Atg	8,42	0,92	0	probably_damaging	1	neutral	0,26	neutral	0,44	deleterious	-5,97	neutral	-1,82	medium_impact	3,05	neutral	0,65	damaging	0,12	deleterious	3,54	23,1	0,25	0,45	neutral	0,49	disease	0,81	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,78	low_impact	-3,55	medium_impact	-0,05	medium_impact	1,42	0,68	0,85	50	8,83	P	0,54	P	0,31	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14198	14198	G	T	MI.23203	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	476	159	T	K	aCa/aAa	-14,04	0	0	possibly_damaging	0,74	neutral	0,29	neutral	2,27	deleterious	-3,9	neutral	-1,48	medium_impact	2,16	neutral	0,78	neutral	0,56	deleterious	4,07	23,7	0,35	0,5	neutral	0,2	disease	0,79	disease	0,56	disease	0,78	6	neutral	0,8	neutral	0,28	NA	0	deleterious	0,62	low_impact	-1,21	medium_impact	-0,01	medium_impact	0,67	0,84	0,9	49,12	8,85	N	0,34	N	0,75	NA	NA	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14198	14198	G	A	MI.23204	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	476	159	T	M	aCa/aTa	-14,04	0	0	probably_damaging	0,98	neutral	0,23	neutral	2,31	deleterious	-5,2	neutral	-1,84	low_impact	1,12	neutral	0,89	neutral	0,93	deleterious	2,76	21,2	0,48	0,55	neutral	0,32	neutral	0,43	neutral	0,31	neutral	0,48	0	deleterious	0,98	neutral	0,13	neutral	-2	deleterious	0,68	low_impact	-2,35	medium_impact	-0,09	medium_impact	-0,2	0,89	0,9	49,12	8,85	N	0,51	P	0,78	NA	NA	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14199	14199	T	G	MI.23205	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	475	159	T	P	Aca/Cca	0,4	0	0	probably_damaging	0,9	neutral	0,17	neutral	2,27	deleterious	-4,83	neutral	-2,29	medium_impact	2,16	neutral	0,83	neutral	0,47	deleterious	3,85	23,4	0,2	0,45	neutral	0,31	disease	0,89	disease	0,57	disease	0,82	6	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,75	low_impact	-1,67	medium_impact	-0,18	medium_impact	0,67	0,72	0,85	49,12	8,85	N	0,36	N	0,82	NA	NA	0,53	rs2857288	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14199	14199	T	C	MI.23206	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	475	159	T	A	Aca/Gca	0,4	0	0	benign	0,05	neutral	0,42	neutral	2,34	neutral	-2,73	neutral	-0,24	neutral_impact	-0,4	neutral	0,93	neutral	0,93	deleterious	2,07	16,69	0,69	0,75	neutral	0,15	neutral	0,4	neutral	0,29	neutral	0,44	1	neutral	0,54	deleterious	0,69	neutral	-6	neutral	0,15	medium_impact	0,38	medium_impact	0,13	low_impact	-1,48	0,76	0,85	49,12	8,85	N	0,41	N	0,43	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14199	14199	T	A	MI.23207	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	475	159	T	S	Aca/Tca	0,4	0	0	benign	0,16	neutral	0,3	neutral	2,3	deleterious	-3,04	neutral	1,86	neutral_impact	-0,5	neutral	0,86	neutral	0,98	neutral	0,97	10,49	0,46	0,55	neutral	0,11	neutral	0,31	neutral	0,23	neutral	0,44	1	neutral	0,65	deleterious	0,57	neutral	-6	neutral	0,18	medium_impact	-0,14	medium_impact	0	low_impact	-1,56	0,7	0,85	49,12	8,85	N	0,48	N	0,16	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14200	14200	T	A	MI.23208	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	474	158	W	C	tgA/tgT	-0,29	0	0,07	probably_damaging	1	neutral	0,13	neutral	2,3	deleterious	-8,07	deleterious	-12,96	high_impact	3,96	neutral	0,68	damaging	0,05	deleterious	4,6	24,4	0,27	0,45	disease	0,93	disease	0,97	disease	0,85	disease	0,88	8	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	-0,25	high_impact	2,18	0,28	0,8	48,67	8,64	N	0,45	N	0,96	NA	NA	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14200	14200	T	G	MI.23209	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	474	158	W	C	tgA/tgC	-0,29	0	0,07	probably_damaging	1	neutral	0,13	neutral	2,3	deleterious	-8,07	deleterious	-12,96	high_impact	3,96	neutral	0,68	damaging	0,05	deleterious	4,46	24,2	0,27	0,45	disease	0,93	disease	0,97	disease	0,85	disease	0,88	8	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	-0,25	high_impact	2,18	0,28	0,8	48,67	8,64	N	0,42	N	0,96	NA	NA	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6110	6110	A	T	MI.2321	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	207	69	M	I	atA/atT	5,91	1	0	benign	0,17	deleterious	0	neutral	2,84	neutral	0,47	neutral	-2,17	high_impact	4,12	damaging	0,51	damaging	0,08	neutral	1,65	14,13	0,51	0,6	neutral	0,33	disease	0,94	disease	0,62	disease	0,8	6	deleterious	1	neutral	0,42	deleterious	2	neutral	0,35	medium_impact	-0,11	low_impact	-1,48	high_impact	2,71	0,58	0,9	7,02	12,6	P	0,5	N	0,56	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14201	14201	C	G	MI.23210	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	473	158	W	S	tGa/tCa	-3,73	0	0	probably_damaging	1	neutral	0,44	neutral	2,33	deleterious	-6,51	deleterious	-13,96	high_impact	3,96	neutral	0,67	damaging	0,08	deleterious	4,4	24,1	0,24	0,45	disease	0,87	disease	0,98	disease	0,83	disease	0,89	8	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0,15	high_impact	2,18	0,21	0,8	48,67	8,64	N	0,46	N	0,92	NA	NA	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14201	14201	C	A	MI.23211	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	473	158	W	L	tGa/tTa	-3,73	0	0	probably_damaging	1	neutral	0,73	neutral	2,59	deleterious	-5,31	deleterious	-12,96	medium_impact	3,26	neutral	0,76	damaging	0,07	deleterious	4,8	24,8	0,27	0,45	disease	0,76	disease	0,96	disease	0,82	disease	0,91	8	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,88	low_impact	-3,55	medium_impact	0,45	medium_impact	1,59	0,28	0,8	48,67	8,64	N	0,38	N	0,95	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14202	14202	A	C	MI.23212	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	472	158	W	G	Tga/Gga	2,69	0,98	0	probably_damaging	1	neutral	0,45	neutral	2,32	deleterious	-6,55	deleterious	-12,96	medium_impact	2,98	neutral	0,74	damaging	0,13	deleterious	3,73	23,3	0,25	0,45	disease	0,83	disease	0,96	disease	0,84	disease	0,88	8	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,87	low_impact	-3,55	medium_impact	0,16	medium_impact	1,36	0,28	0,8	48,67	8,64	N	0,49	N	0,9	NA	NA	0,62	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14202	14202	A	G	MI.23213	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	472	158	W	R	Tga/Cga	2,69	0,98	0	probably_damaging	1	neutral	0,26	neutral	2,3	deleterious	-6,64	deleterious	-13,96	high_impact	3,96	neutral	0,68	damaging	0,05	deleterious	3,8	23,4	0,28	0,45	disease	0,87	disease	0,97	disease	0,87	disease	0,9	8	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,05	high_impact	2,18	0,31	0,8	48,67	8,64	P	0,58	P	0,96	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14204	14204	C	T	MI.23214	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	470	157	G	D	gGt/gAt	-7,17	0	0	probably_damaging	0,99	neutral	0,11	neutral	2,13	deleterious	-5,45	deleterious	-6,75	medium_impact	3,33	neutral	0,73	damaging	0,21	deleterious	4,16	23,8	0,17	0,45	disease	0,53	disease	0,96	disease	0,83	disease	0,93	9	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,86	low_impact	-2,63	medium_impact	-0,3	medium_impact	1,65	0,7	0,85	48,67	9	N	0,35	N	0,96	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14204	14204	C	A	MI.23215	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	470	157	G	V	gGt/gTt	-7,17	0	0	probably_damaging	0,96	neutral	1	neutral	2,26	deleterious	-5,73	deleterious	-8,61	medium_impact	2,63	neutral	0,78	neutral	0,36	deleterious	4,43	24,2	0,3	0,45	neutral	0,39	disease	0,96	disease	0,74	disease	0,85	7	neutral	0,96	deleterious	0,52	deleterious	1	deleterious	0,84	low_impact	-2,06	high_impact	1,87	medium_impact	1,06	0,8	0,85	48,67	9	N	0,33	N	0,98	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14204	14204	C	G	MI.23216	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	470	157	G	A	gGt/gCt	-7,17	0	0	possibly_damaging	0,8	neutral	0,24	neutral	2,41	deleterious	-4,4	deleterious	-5,68	low_impact	1,87	neutral	0,75	neutral	0,56	deleterious	3,43	23	0,47	0,55	neutral	0,16	disease	0,73	disease	0,59	disease	0,55	1	neutral	0,87	neutral	0,22	neutral	-3	deleterious	0,7	low_impact	-1,35	medium_impact	-0,07	medium_impact	0,43	0,91	0,95	48,67	9	N	0,36	N	0,78	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14205	14205	C	A	MI.23217	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	469	157	G	C	Ggt/Tgt	2	0,46	0	benign	0,24	neutral	0,06	neutral	2,17	deleterious	-7,01	deleterious	-8,27	low_impact	1,9	neutral	0,79	damaging	0,21	deleterious	4,69	24,6	0,22	0,45	disease	0,67	disease	0,97	disease	0,73	disease	0,85	7	neutral	0,93	neutral	0,41	neutral	-6	deleterious	0,47	medium_impact	-0,34	medium_impact	-0,46	medium_impact	0,45	0,84	0,9	48,67	9	N	0,39	N	0,97	NA	NA	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14205	14205	C	T	MI.23218	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	469	157	G	S	Ggt/Agt	2	0,46	0	probably_damaging	0,96	neutral	0,16	neutral	2,33	deleterious	-4,66	deleterious	-5,72	high_impact	3,67	neutral	0,72	neutral	0,3	deleterious	4,51	24,3	0,4	0,5	neutral	0,32	disease	0,94	disease	0,76	disease	0,87	7	neutral	0,98	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-2,06	medium_impact	-0,19	medium_impact	1,93	0,96	1	48,67	9	N	0,48	N	1	NA	NA	0,66	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14205	14205	C	G	MI.23219	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	469	157	G	R	Ggt/Cgt	2	0,46	0	probably_damaging	0,99	neutral	0,15	neutral	2,13	deleterious	-5,95	deleterious	-7,71	high_impact	3,67	neutral	0,74	damaging	0,17	deleterious	4,3	24	0,16	0,45	neutral	0,49	disease	0,97	disease	0,84	disease	0,94	9	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,88	low_impact	-2,63	medium_impact	-0,21	medium_impact	1,93	0,87	0,9	48,67	9	N	0,51	P	1	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6110	6110	A	C	MI.2322	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	207	69	M	I	atA/atC	5,91	1	0	benign	0,17	deleterious	0	neutral	2,84	neutral	0,47	neutral	-2,17	high_impact	4,12	damaging	0,51	damaging	0,08	neutral	1,46	13,13	0,51	0,6	neutral	0,33	disease	0,94	disease	0,62	disease	0,8	6	deleterious	1	neutral	0,42	deleterious	2	neutral	0,35	medium_impact	-0,11	low_impact	-1,48	high_impact	2,71	0,58	0,9	7,02	12,6	P	0,5	N	0,56	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14207	14207	G	C	MI.23220	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	467	156	T	S	aCt/aGt	-3,73	0	0	benign	0,37	neutral	0,21	neutral	2,29	deleterious	-3,04	neutral	-1	neutral_impact	0,34	neutral	0,89	neutral	0,98	neutral	-0,4	0,38	0,47	0,55	neutral	0,24	neutral	0,34	neutral	0,32	neutral	0,44	1	neutral	0,75	neutral	0,42	neutral	-6	neutral	0,33	medium_impact	-0,58	medium_impact	-0,11	medium_impact	-0,86	0,74	0,85	50	8,71	P	0,59	P	0,47	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14207	14207	G	T	MI.23221	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	467	156	T	N	aCt/aAt	-3,73	0	0	possibly_damaging	0,82	neutral	0,23	neutral	2,25	deleterious	-4,26	deleterious	-3,12	medium_impact	2,35	neutral	0,76	neutral	0,52	deleterious	3,11	22,5	0,44	0,55	neutral	0,37	disease	0,85	disease	0,55	disease	0,81	6	neutral	0,88	neutral	0,21	NA	0	deleterious	0,73	low_impact	-1,4	medium_impact	-0,09	medium_impact	0,83	0,85	0,9	50	8,71	N	0,45	N	0,71	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14207	14207	G	A	MI.23222	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	467	156	T	I	aCt/aTt	-3,73	0	0	benign	0,36	neutral	0,49	neutral	2,36	deleterious	-3,86	deleterious	-3,26	medium_impact	2,35	neutral	0,77	neutral	0,48	deleterious	1,98	16,09	0,45	0,55	neutral	0,27	disease	0,78	disease	0,53	disease	0,75	5	neutral	0,43	deleterious	0,57	neutral	-3	neutral	0,39	medium_impact	-0,57	medium_impact	0,2	medium_impact	0,83	0,84	0,9	50	8,71	N	0,36	N	0,67	NA	NA	0,54	rs879217937	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14208	14208	T	C	MI.23223	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	466	156	T	A	Act/Gct	0,63	0	0	benign	0,02	neutral	0,34	neutral	2,42	neutral	-2,73	neutral	-0,14	neutral_impact	-0,14	neutral	0,95	neutral	0,99	neutral	-1,19	0,01	0,64	0,7	neutral	0,13	neutral	0,46	neutral	0,37	neutral	0,43	1	neutral	0,65	deleterious	0,66	neutral	-6	neutral	0,16	medium_impact	0,75	medium_impact	0,05	low_impact	-1,26	0,73	0,85	50	8,71	N	0,49	N	0,15	NA	NA	0,16	.	.	.	.	.	.	COSM1138249	.	.	.	.	.	.	.	.
chrM	14208	14208	T	G	MI.23224	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	466	156	T	P	Act/Cct	0,63	0	0	possibly_damaging	0,76	neutral	0,1	neutral	2,25	deleterious	-4,83	deleterious	-3,19	medium_impact	2,69	neutral	0,77	neutral	0,38	deleterious	3,61	23,2	0,2	0,45	neutral	0,48	disease	0,93	disease	0,55	disease	0,83	6	neutral	0,93	neutral	0,17	NA	0	deleterious	0,78	low_impact	-1,26	medium_impact	-0,32	medium_impact	1,11	0,77	0,85	50	8,71	N	0,41	N	0,81	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14208	14208	T	A	MI.23225	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	466	156	T	S	Act/Tct	0,63	0	0	benign	0,37	neutral	0,21	neutral	2,29	deleterious	-3,04	neutral	-1	neutral_impact	0,34	neutral	0,89	neutral	0,98	deleterious	0,04	2,93	0,47	0,55	neutral	0,24	neutral	0,34	neutral	0,32	neutral	0,44	1	neutral	0,75	neutral	0,42	neutral	-6	neutral	0,33	medium_impact	-0,58	medium_impact	-0,11	medium_impact	-0,86	0,74	0,85	50	8,71	P	0,57	P	0,47	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14210	14210	A	C	MI.23226	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	464	155	V	G	gTt/gGt	-9	0	0	probably_damaging	1	neutral	0,14	neutral	2,19	deleterious	-5,02	deleterious	-6,4	medium_impact	2,88	neutral	0,76	neutral	0,5	deleterious	3,6	23,2	0,18	0,45	disease	0,82	disease	0,9	disease	0,73	disease	0,83	7	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,86	low_impact	-3,55	medium_impact	-0,23	medium_impact	1,27	0,7	0,85	44,25	8,13	N	0,32	N	0,86	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14210	14210	A	G	MI.23227	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	464	155	V	A	gTt/gCt	-9	0	0	probably_damaging	1	neutral	0,26	neutral	2,26	deleterious	-3,61	deleterious	-3,6	medium_impact	2,23	neutral	0,86	neutral	0,74	deleterious	3,68	23,3	0,26	0,45	disease	0,53	disease	0,83	disease	0,61	disease	0,62	2	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,81	low_impact	-3,55	medium_impact	-0,05	medium_impact	0,73	0,64	0,8	44,25	8,13	N	0,33	N	0,7	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14210	14210	A	T	MI.23228	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	464	155	V	D	gTt/gAt	-9	0	0	probably_damaging	1	neutral	0,06	neutral	2,18	deleterious	-5,67	deleterious	-6,33	medium_impact	3,44	neutral	0,77	neutral	0,4	deleterious	4,25	23,9	0,09	0,35	disease	0,87	disease	0,94	disease	0,8	disease	0,92	8	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,88	low_impact	-3,55	medium_impact	-0,46	medium_impact	1,74	0,78	0,85	44,25	8,13	N	0,45	N	0,94	NA	NA	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14211	14211	C	T	MI.23229	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	463	155	V	I	Gtt/Att	4,29	0,18	0	probably_damaging	1	neutral	0,59	neutral	2,38	neutral	-2,26	neutral	-0,66	low_impact	0,85	neutral	0,8	neutral	0,93	deleterious	0,88	9,94	0,36	0,5	neutral	0,19	neutral	0,23	neutral	0,39	neutral	0,43	2	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,67	low_impact	-3,55	medium_impact	0,29	medium_impact	-0,43	0,85	0,9	44,25	8,13	N	0,36	N	0,41	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6111	6111	G	C	MI.2323	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	208	70	V	L	Gta/Cta	0,13	0,95	0	probably_damaging	0,99	neutral	0,06	neutral	2,78	neutral	-0,18	neutral	-1,9	medium_impact	3,25	damaging	0,58	neutral	0,54	deleterious	3,39	23	0,4	0,55	neutral	0,38	disease	0,68	neutral	0,5	neutral	0,49	0	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,74	low_impact	-2,64	medium_impact	-0,47	medium_impact	1,9	0,46	0,9	2,14	6,63	N	0,48	N	0,55	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14211	14211	C	A	MI.23230	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	463	155	V	F	Gtt/Ttt	4,29	0,18	0	probably_damaging	1	neutral	0,53	neutral	2,32	deleterious	-4,72	deleterious	-4,07	medium_impact	2,05	neutral	0,85	neutral	0,71	deleterious	4,36	24,1	0,21	0,45	disease	0,62	disease	0,91	disease	0,51	disease	0,61	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,84	low_impact	-3,55	medium_impact	0,24	medium_impact	0,58	0,8	0,85	44,25	8,13	N	0,33	N	0,93	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14211	14211	C	G	MI.23231	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	463	155	V	L	Gtt/Ctt	4,29	0,18	0	probably_damaging	1	neutral	1	neutral	2,73	neutral	-2,68	neutral	-2,07	low_impact	1,38	neutral	0,84	neutral	0,93	deleterious	2,37	18,65	0,36	0,5	neutral	0,22	disease	0,68	neutral	0,41	disease	0,52	0	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,73	low_impact	-3,55	high_impact	1,87	medium_impact	0,02	0,78	0,85	44,25	8,13	N	0,32	N	0,62	NA	NA	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14213	14213	A	T	MI.23232	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	461	154	V	E	gTa/gAa	-6,02	0	0	probably_damaging	0,97	neutral	0,11	neutral	2,29	deleterious	-5,19	deleterious	-4,68	medium_impact	2,98	neutral	0,77	neutral	0,39	deleterious	4,42	24,2	0,1	0,4	disease	0,79	disease	0,94	disease	0,75	disease	0,89	8	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,86	low_impact	-2,18	medium_impact	-0,3	medium_impact	1,36	0,7	0,85	15,49	11,76	N	0,3	N	0,92	NA	NA	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14213	14213	A	C	MI.23233	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	461	154	V	G	gTa/gGa	-6,02	0	0	probably_damaging	0,97	neutral	0,17	neutral	2,19	deleterious	-5,02	deleterious	-5,11	medium_impact	2,52	neutral	0,8	neutral	0,54	deleterious	3,5	23,1	0,14	0,4	disease	0,79	disease	0,87	disease	0,66	disease	0,76	5	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,83	low_impact	-2,18	medium_impact	-0,18	medium_impact	0,97	0,75	0,85	15,49	11,76	N	0,28	N	0,88	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14213	14213	A	G	MI.23234	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	461	154	V	A	gTa/gCa	-6,02	0	0	possibly_damaging	0,8	neutral	0,36	neutral	2,23	deleterious	-3,61	deleterious	-2,64	medium_impact	2,08	neutral	0,88	neutral	0,93	deleterious	2,44	19,11	0,26	0,45	neutral	0,49	disease	0,78	disease	0,55	disease	0,59	2	neutral	0,81	neutral	0,28	NA	0	deleterious	0,7	low_impact	-1,35	medium_impact	0,07	medium_impact	0,6	0,7	0,85	15,49	11,76	N	0,29	N	0,48	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14214	14214	C	T	MI.23235	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	460	154	V	M	Gta/Ata	1,77	0	0	probably_damaging	0,95	neutral	0,15	neutral	2,26	deleterious	-4,64	neutral	-1,66	low_impact	1,88	neutral	0,86	neutral	0,72	neutral	1,4	12,78	0,32	0,5	disease	0,51	disease	0,55	neutral	0,36	disease	0,51	0	neutral	0,97	neutral	0,1	neutral	-2	deleterious	0,71	low_impact	-1,97	medium_impact	-0,21	medium_impact	0,44	0,81	0,85	15,49	11,76	N	0,4	N	0,68	NA	NA	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14214	14214	C	G	MI.23236	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	460	154	V	L	Gta/Cta	1,77	0	0	benign	0,05	neutral	0,9	neutral	2,4	neutral	-2,68	neutral	-1,38	neutral_impact	0,52	neutral	0,9	neutral	0,9	neutral	0,94	10,29	0,34	0,5	neutral	0,16	disease	0,53	neutral	0,29	neutral	0,43	1	neutral	0,03	deleterious	0,93	neutral	-6	neutral	0,18	medium_impact	0,38	medium_impact	0,74	medium_impact	-0,7	0,77	0,85	15,49	11,76	N	0,29	N	0,67	NA	NA	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14214	14214	C	A	MI.23237	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	460	154	V	L	Gta/Tta	1,77	0	0	benign	0,05	neutral	0,9	neutral	2,4	neutral	-2,68	neutral	-1,38	neutral_impact	0,52	neutral	0,9	neutral	0,9	neutral	1,18	11,65	0,34	0,5	neutral	0,16	disease	0,53	neutral	0,29	neutral	0,43	1	neutral	0,03	deleterious	0,93	neutral	-6	neutral	0,18	medium_impact	0,38	medium_impact	0,74	medium_impact	-0,7	0,77	0,85	15,49	11,76	N	0,29	N	0,67	NA	NA	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14216	14216	A	C	MI.23238	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	458	153	V	G	gTa/gGa	-3,73	0	0	probably_damaging	0,91	neutral	0,18	neutral	2,15	deleterious	-3,71	deleterious	-5,64	medium_impact	3,08	neutral	0,71	neutral	0,5	deleterious	3,59	23,2	0,14	0,4	disease	0,67	disease	0,89	disease	0,61	disease	0,82	6	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-1,72	medium_impact	-0,16	medium_impact	1,44	0,7	0,85	49,56	8,78	N	0,31	N	0,9	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14216	14216	A	T	MI.23239	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	458	153	V	E	gTa/gAa	-3,73	0	0	probably_damaging	0,97	neutral	0,07	neutral	2,15	deleterious	-3,41	deleterious	-4,68	medium_impact	3,08	neutral	0,73	neutral	0,45	deleterious	4,44	24,2	0,1	0,4	disease	0,68	disease	0,94	disease	0,72	disease	0,89	8	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,86	low_impact	-2,18	medium_impact	-0,42	medium_impact	1,44	0,65	0,8	49,56	8,78	N	0,32	N	0,9	NA	NA	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6111	6111	G	T	MI.2324	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	208	70	V	L	Gta/Tta	0,13	0,95	0	probably_damaging	0,99	neutral	0,06	neutral	2,78	neutral	-0,18	neutral	-1,9	medium_impact	3,25	damaging	0,58	neutral	0,54	deleterious	3,54	23,1	0,4	0,55	neutral	0,38	disease	0,68	neutral	0,5	neutral	0,49	0	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,74	low_impact	-2,64	medium_impact	-0,47	medium_impact	1,9	0,46	0,9	2,14	6,63	N	0,48	N	0,55	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14216	14216	A	G	MI.23240	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	458	153	V	A	gTa/gCa	-3,73	0	0	benign	0,23	neutral	0,22	neutral	2,2	neutral	-1,88	deleterious	-2,94	medium_impact	3,08	neutral	0,72	neutral	0,63	deleterious	3,74	23,3	0,31	0,45	neutral	0,39	disease	0,79	disease	0,58	disease	0,78	6	neutral	0,74	deleterious	0,5	neutral	-3	deleterious	0,47	medium_impact	-0,32	medium_impact	-0,1	medium_impact	1,44	0,71	0,85	49,56	8,78	N	0,4	N	0,65	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14217	14217	C	G	MI.23241	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	457	153	V	L	Gta/Cta	8,19	0,96	0	possibly_damaging	0,78	neutral	1	neutral	2,46	neutral	2,02	neutral	-0,78	neutral_impact	0,16	neutral	0,83	neutral	0,93	deleterious	2,09	16,81	0,25	0,45	neutral	0,11	neutral	0,3	neutral	0,31	neutral	0,43	2	neutral	0,78	deleterious	0,61	neutral	-3	deleterious	0,61	low_impact	-1,3	high_impact	1,87	low_impact	-1,01	0,72	0,85	49,56	8,78	N	0,52	P	0,36	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14217	14217	C	T	MI.23242	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	457	153	V	M	Gta/Ata	8,19	0,96	0	probably_damaging	0,99	neutral	0,1	neutral	2,21	neutral	-0,01	neutral	-0,18	low_impact	0,9	neutral	0,87	neutral	0,77	neutral	1,52	13,4	0,33	0,5	neutral	0,23	disease	0,63	neutral	0,3	neutral	0,46	1	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,7	low_impact	-2,63	medium_impact	-0,32	medium_impact	-0,39	0,81	0,85	49,56	8,78	P	0,53	P	0,33	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14217	14217	C	A	MI.23243	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	457	153	V	L	Gta/Tta	8,19	0,96	0	possibly_damaging	0,78	neutral	1	neutral	2,46	neutral	2,02	neutral	-0,78	neutral_impact	0,16	neutral	0,83	neutral	0,93	deleterious	2,34	18,42	0,25	0,45	neutral	0,11	neutral	0,3	neutral	0,31	neutral	0,43	2	neutral	0,78	deleterious	0,61	neutral	-3	deleterious	0,61	low_impact	-1,3	high_impact	1,87	low_impact	-1,01	0,72	0,85	49,56	8,78	N	0,52	P	0,36	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14218	14218	T	A	MI.23244	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	456	152	L	F	ttA/ttT	-1,44	0	0,01	probably_damaging	0,96	neutral	0,26	neutral	2,17	deleterious	-4,41	neutral	-1,62	low_impact	1,25	neutral	0,91	neutral	0,92	deleterious	2,78	21,2	0,37	0,5	neutral	0,47	disease	0,7	neutral	0,37	disease	0,57	1	neutral	0,97	neutral	0,15	neutral	-2	deleterious	0,76	low_impact	-2,06	medium_impact	-0,05	medium_impact	-0,09	0,73	0,85	46,9	8,18	N	0,4	N	0,65	NA	NA	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14219	14219	A	G	MI.23245	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	455	152	L	S	tTa/tCa	-5,1	0	0	probably_damaging	0,96	neutral	0,09	neutral	2,17	deleterious	-5,22	deleterious	-4,53	medium_impact	2,46	neutral	0,74	neutral	0,5	deleterious	3,98	23,6	0,21	0,45	disease	0,67	disease	0,85	disease	0,65	disease	0,79	6	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,83	low_impact	-2,06	medium_impact	-0,35	medium_impact	0,92	0,79	0,85	46,9	8,18	N	0,32	N	0,84	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14219	14219	A	C	MI.23246	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	455	152	L	W	tTa/tGa	-5,1	0	0	probably_damaging	0,99	neutral	0,16	neutral	2,16	deleterious	-7,24	deleterious	-4,07	medium_impact	2,72	neutral	0,83	neutral	0,43	deleterious	3,57	23,1	0,13	0,4	disease	0,85	disease	0,92	disease	0,68	disease	0,82	6	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,87	low_impact	-2,63	medium_impact	-0,19	medium_impact	1,14	0,7	0,85	46,9	8,18	N	0,34	N	0,89	NA	NA	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14220	14220	A	T	MI.23247	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	454	152	L	M	Tta/Ata	2,46	0	0	probably_damaging	0,97	neutral	0,14	neutral	2,23	deleterious	-4,39	neutral	-0,77	low_impact	1,18	neutral	0,86	neutral	0,97	deleterious	2,25	17,83	0,27	0,45	neutral	0,21	neutral	0,1	neutral	0,24	neutral	0,26	5	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,66	low_impact	-2,18	medium_impact	-0,23	medium_impact	-0,15	0,8	0,85	46,9	8,18	N	0,51	P	0,24	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14220	14220	A	C	MI.23248	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	454	152	L	V	Tta/Gta	2,46	0	0	benign	0,15	neutral	0,35	neutral	2,29	deleterious	-3,31	neutral	-1,75	low_impact	0,87	neutral	0,94	neutral	0,95	deleterious	2,12	16,96	0,31	0,5	neutral	0,16	disease	0,65	neutral	0,35	neutral	0,46	1	neutral	0,59	deleterious	0,6	neutral	-6	neutral	0,24	medium_impact	-0,11	medium_impact	0,06	medium_impact	-0,41	0,8	0,85	46,9	8,18	N	0,45	N	0,53	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14221	14221	T	G	MI.23249	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	453	151	W	C	tgA/tgC	-4,64	0	0	probably_damaging	1	deleterious	0,03	neutral	2,31	deleterious	-7,1	deleterious	-12,87	medium_impact	2,98	neutral	0,72	damaging	0,06	deleterious	4,43	24,2	0,42	0,55	disease	0,71	disease	0,9	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,88	low_impact	-3,55	medium_impact	-0,63	medium_impact	1,36	0,36	0,8	50,44	8,78	N	0,32	N	0,96	NA	NA	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6111	6111	G	A	MI.2325	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	208	70	V	M	Gta/Ata	0,13	0,95	0	probably_damaging	1	deleterious	0	neutral	2,6	neutral	-1,96	neutral	-1,9	high_impact	4,64	neutral	0,63	neutral	0,59	deleterious	3,59	23,2	0,39	0,55	disease	0,63	disease	0,71	disease	0,6	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	3,19	0,74	0,9	2,14	6,63	P	0,59	P	0,82	disease_causing	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14221	14221	T	A	MI.23250	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	453	151	W	C	tgA/tgT	-4,64	0	0	probably_damaging	1	deleterious	0,03	neutral	2,31	deleterious	-7,1	deleterious	-12,87	medium_impact	2,98	neutral	0,72	damaging	0,06	deleterious	4,7	24,6	0,42	0,55	disease	0,71	disease	0,9	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,88	low_impact	-3,55	medium_impact	-0,63	medium_impact	1,36	0,36	0,8	50,44	8,78	N	0,31	N	0,96	NA	NA	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14222	14222	C	A	MI.23251	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	452	151	W	L	tGa/tTa	-4,19	0	0	probably_damaging	1	neutral	1	neutral	2,51	deleterious	-4,25	deleterious	-12,87	medium_impact	2,25	neutral	0,77	damaging	0,13	deleterious	4,91	24,9	0,34	0,5	neutral	0,36	disease	0,8	disease	0,72	disease	0,63	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,8	low_impact	-3,55	high_impact	1,87	medium_impact	0,75	0,38	0,8	50,44	8,78	N	0,23	N	0,95	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14222	14222	C	G	MI.23252	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	452	151	W	S	tGa/tCa	-4,19	0	0	probably_damaging	1	neutral	0,1	neutral	2,38	deleterious	-5,45	deleterious	-13,82	medium_impact	2,87	neutral	0,72	damaging	0,15	deleterious	4,32	24	0,31	0,5	neutral	0,35	disease	0,86	disease	0,75	disease	0,78	6	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,82	low_impact	-3,55	medium_impact	-0,32	medium_impact	1,26	0,46	0,8	50,44	8,78	N	0,43	N	0,92	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14223	14223	A	G	MI.23253	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	451	151	W	R	Tga/Cga	0,63	0	0	probably_damaging	1	neutral	0,06	neutral	2,31	deleterious	-5,59	deleterious	-13,86	high_impact	3,67	neutral	0,74	damaging	0,05	deleterious	3,83	23,4	0,41	0,5	neutral	0,35	disease	0,89	disease	0,81	disease	0,83	7	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,82	low_impact	-3,55	medium_impact	-0,46	medium_impact	1,93	0,42	0,8	50,44	8,78	N	0,44	N	0,96	NA	NA	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14223	14223	A	C	MI.23254	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	451	151	W	G	Tga/Gga	0,63	0	0	probably_damaging	1	neutral	0,12	neutral	2,33	deleterious	-5,63	deleterious	-12,86	low_impact	1,73	neutral	0,77	damaging	0,27	deleterious	3,73	23,3	0,29	0,45	neutral	0,19	neutral	0,36	disease	0,71	neutral	0,48	0	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,7	low_impact	-3,55	medium_impact	-0,27	medium_impact	0,31	0,57	0,8	50,44	8,78	N	0,36	N	0,9	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14225	14225	C	T	MI.23255	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	449	150	R	H	cGt/cAt	-1,89	0	0	possibly_damaging	0,8	neutral	0,44	neutral	2,31	deleterious	-5,32	neutral	0,02	low_impact	1,79	neutral	0,77	neutral	0,39	deleterious	2,82	21,5	0,58	0,65	neutral	0,31	neutral	0,5	neutral	0,38	disease	0,51	0	neutral	0,8	neutral	0,32	neutral	-3	deleterious	0,62	low_impact	-1,35	medium_impact	0,15	medium_impact	0,36	0,98	1	15,93	11,92	N	0,39	N	0,55	NA	NA	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14225	14225	C	A	MI.23256	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	449	150	R	L	cGt/cTt	-1,89	0	0	benign	0,14	neutral	1	neutral	2,45	deleterious	-4,56	neutral	-0,2	low_impact	1,45	neutral	0,82	neutral	0,42	neutral	1,17	11,6	0,44	0,55	neutral	0,16	disease	0,8	neutral	0,5	disease	0,71	4	neutral	0,14	deleterious	0,93	neutral	-6	neutral	0,26	medium_impact	-0,07	high_impact	1,87	medium_impact	0,08	0,58	0,8	15,93	11,92	N	0,24	N	0,78	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14225	14225	C	G	MI.23257	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	449	150	R	P	cGt/cCt	-1,89	0	0	possibly_damaging	0,75	neutral	0,18	neutral	2,47	deleterious	-5,6	neutral	-0,55	low_impact	1,79	neutral	0,74	neutral	0,3	deleterious	3,14	22,6	0,25	0,45	neutral	0,34	disease	0,91	disease	0,66	disease	0,82	6	neutral	0,87	neutral	0,22	neutral	-3	deleterious	0,71	low_impact	-1,23	medium_impact	-0,16	medium_impact	0,36	0,68	0,85	15,93	11,92	N	0,39	N	0,83	NA	NA	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14226	14226	G	T	MI.23258	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	448	150	R	S	Cgt/Agt	-2,81	0	0,01	benign	0,34	neutral	0,37	neutral	2,45	deleterious	-4,29	neutral	2	neutral_impact	0,24	neutral	0,88	neutral	0,87	deleterious	0,8	9,48	0,34	0,5	neutral	0,16	disease	0,53	neutral	0,37	neutral	0,44	1	neutral	0,56	deleterious	0,52	neutral	-6	neutral	0,33	medium_impact	-0,53	medium_impact	0,08	medium_impact	-0,94	0,72	0,85	15,93	11,92	N	0,39	N	0,56	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14226	14226	G	A	MI.23259	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	448	150	R	C	Cgt/Tgt	-2,81	0	0,01	benign	0,01	neutral	0,16	neutral	2,31	deleterious	-6,86	neutral	1,15	neutral_impact	0,24	neutral	0,9	neutral	0,7	neutral	1,63	14,04	0,43	0,55	neutral	0,47	disease	0,82	neutral	0,3	disease	0,59	2	neutral	0,84	deleterious	0,58	neutral	-6	neutral	0,26	medium_impact	1,03	medium_impact	-0,19	medium_impact	-0,94	0,97	1	15,93	11,92	N	0,42	N	0,62	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6112	6112	T	A	MI.2326	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	209	70	V	E	gTa/gAa	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-4,01	deleterious	-3,81	high_impact	4,99	damaging	0,58	neutral	0,49	deleterious	4,61	24,4	0,11	0,55	disease	0,78	disease	0,83	disease	0,71	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,51	0,37	0,9	2,14	6,63	P	0,72	P	0,84	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14226	14226	G	C	MI.23260	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	448	150	R	G	Cgt/Ggt	-2,81	0	0,01	benign	0,34	neutral	0,47	neutral	2,39	deleterious	-4,86	neutral	0,23	neutral_impact	-1,02	neutral	0,88	neutral	0,92	deleterious	2,01	16,28	0,38	0,5	neutral	0,12	neutral	0,18	neutral	0,43	neutral	0,26	5	neutral	0,45	deleterious	0,57	neutral	-6	neutral	0,27	medium_impact	-0,53	medium_impact	0,18	low_impact	-1,99	0,75	0,85	15,93	11,92	N	0,4	N	0,46	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14228	14228	C	A	MI.23261	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	446	149	G	V	gGg/gTg	-6,94	0	0	probably_damaging	1	neutral	0,67	neutral	2,28	deleterious	-5,73	deleterious	-6,44	high_impact	3,62	neutral	0,72	damaging	0,12	deleterious	4,28	24	0,23	0,45	disease	0,58	disease	0,96	disease	0,84	disease	0,93	9	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	0,38	medium_impact	1,89	0,84	0,9	49,56	8,82	N	0,39	N	0,89	NA	NA	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14228	14228	C	T	MI.23262	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	446	149	G	E	gGg/gAg	-6,94	0	0	probably_damaging	1	neutral	0,18	neutral	2,31	deleterious	-5,32	deleterious	-5,72	high_impact	3,96	neutral	0,64	damaging	0,09	deleterious	4,31	24	0,35	0,5	disease	0,61	disease	0,96	disease	0,86	disease	0,94	9	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,16	high_impact	2,18	0,74	0,85	49,56	8,82	N	0,5	N	0,9	NA	NA	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14228	14228	C	G	MI.23263	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	446	149	G	A	gGg/gCg	-6,94	0	0	probably_damaging	1	neutral	0,43	neutral	2,31	deleterious	-4,4	deleterious	-3,77	medium_impact	2,68	neutral	0,8	neutral	0,79	deleterious	2,25	17,86	0,41	0,5	neutral	0,22	disease	0,91	disease	0,78	disease	0,67	3	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,81	low_impact	-3,55	medium_impact	0,14	medium_impact	1,11	0,83	0,85	49,56	8,82	N	0,35	N	0,37	NA	NA	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14229	14229	C	G	MI.23264	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	445	149	G	R	Ggg/Cgg	2,69	0,76	0	probably_damaging	1	neutral	0,26	neutral	2,26	deleterious	-5,95	deleterious	-5,79	high_impact	3,96	neutral	0,62	damaging	0,06	deleterious	4,28	24	0,24	0,45	disease	0,69	disease	0,96	disease	0,87	disease	0,93	9	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,05	high_impact	2,18	0,89	0,9	49,56	8,82	N	0,5	N	0,91	NA	NA	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14229	14229	C	A	MI.23265	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	445	149	G	W	Ggg/Tgg	2,69	0,76	0	probably_damaging	1	neutral	0,5	neutral	2,26	deleterious	-8,54	deleterious	-6,49	high_impact	3,96	neutral	0,63	damaging	0,08	deleterious	5,05	25,2	0,24	0,45	disease	0,93	disease	0,97	disease	0,87	disease	0,9	8	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	0,21	high_impact	2,18	0,68	0,85	49,56	8,82	N	0,49	N	0,91	NA	NA	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14231	14231	T	A	MI.23266	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	443	148	Y	F	tAt/tTt	0,17	0,13	0	probably_damaging	1	neutral	0,67	neutral	2,31	neutral	-2,93	deleterious	-2,98	low_impact	1,77	neutral	0,72	neutral	0,52	deleterious	2,51	19,52	0,42	0,55	neutral	0,33	neutral	0,46	neutral	0,43	neutral	0,46	1	deleterious	1	neutral	0,34	neutral	-2	deleterious	0,74	low_impact	-3,55	medium_impact	0,38	medium_impact	0,34	0,51	0,8	50	8,78	N	0,31	N	0,6	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14231	14231	T	G	MI.23267	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	443	148	Y	S	tAt/tCt	0,17	0,13	0	probably_damaging	1	neutral	0,57	neutral	2,46	deleterious	-4,84	deleterious	-6,6	low_impact	1,52	neutral	0,83	neutral	0,5	deleterious	2,88	21,8	0,25	0,45	neutral	0,14	disease	0,53	disease	0,56	neutral	0,44	1	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,71	low_impact	-3,55	medium_impact	0,27	medium_impact	0,13	0,48	0,8	50	8,78	N	0,26	N	0,81	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14231	14231	T	C	MI.23268	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	443	148	Y	C	tAt/tGt	0,17	0,13	0	probably_damaging	1	neutral	0,22	neutral	2,28	deleterious	-6,77	deleterious	-5,84	low_impact	1,44	neutral	0,86	neutral	0,91	deleterious	2,02	16,35	0,34	0,5	neutral	0,14	disease	0,72	disease	0,56	disease	0,59	2	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,72	low_impact	-3,55	medium_impact	-0,1	medium_impact	0,07	0,32	0,8	50	8,78	N	0,4	N	0,46	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14232	14232	A	G	MI.23269	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	442	148	Y	H	Tat/Cat	0,17	0,13	0	probably_damaging	1	neutral	0,49	neutral	2,31	deleterious	-5,03	deleterious	-3,67	medium_impact	2,51	neutral	0,83	neutral	0,37	deleterious	2,42	18,93	0,48	0,55	disease	0,52	disease	0,65	disease	0,55	disease	0,65	3	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,79	low_impact	-3,55	medium_impact	0,2	medium_impact	0,96	0,4	0,8	50	8,78	N	0,34	N	0,73	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6112	6112	T	G	MI.2327	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	209	70	V	G	gTa/gGa	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,57	neutral	-2,87	deleterious	-4,45	high_impact	3,54	damaging	0,59	neutral	0,61	deleterious	3,67	23,3	0,15	0,55	disease	0,76	disease	0,76	disease	0,62	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,17	0,61	0,9	2,14	6,63	P	0,5	N	0,71	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14232	14232	A	T	MI.23270	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	442	148	Y	N	Tat/Aat	0,17	0,13	0	probably_damaging	1	neutral	0,29	neutral	2,38	deleterious	-5,32	deleterious	-6,82	medium_impact	2,97	neutral	0,77	damaging	0,23	deleterious	2,58	19,96	0,33	0,5	neutral	0,44	disease	0,77	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,79	low_impact	-3,55	medium_impact	-0,01	medium_impact	1,35	0,42	0,8	50	8,78	N	0,31	N	0,87	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14232	14232	A	C	MI.23271	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	442	148	Y	D	Tat/Gat	0,17	0,13	0	probably_damaging	1	neutral	0,18	neutral	2,38	deleterious	-5,53	deleterious	-7,64	medium_impact	2,34	neutral	0,77	damaging	0,24	deleterious	2,6	20,2	0,3	0,45	disease	0,51	disease	0,84	disease	0,7	disease	0,78	6	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,83	low_impact	-3,55	medium_impact	-0,16	medium_impact	0,82	0,48	0,8	50	8,78	N	0,3	N	0,94	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14233	14233	A	C	MI.23272	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	441	147	D	E	gaT/gaG	2,46	0,81	0,07	possibly_damaging	0,64	neutral	0,23	neutral	2,34	deleterious	-3,18	neutral	-0,59	low_impact	1,8	neutral	0,81	neutral	0,71	deleterious	3,8	23,4	0,54	0,6	neutral	0,2	disease	0,76	disease	0,53	disease	0,71	4	neutral	0,79	neutral	0,3	neutral	-3	deleterious	0,56	low_impact	-1,03	medium_impact	-0,09	medium_impact	0,37	0,78	0,85	46,46	7,68	N	0,38	N	0,57	NA	NA	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14234	14234	T	G	MI.23273	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	440	147	D	A	gAt/gCt	2,69	0,8	0	possibly_damaging	0,56	neutral	0,56	neutral	2,32	deleterious	-4,27	neutral	-0,46	low_impact	1,4	neutral	0,89	neutral	0,83	deleterious	3,03	22,3	0,35	0,5	neutral	0,27	disease	0,76	disease	0,62	disease	0,6	2	neutral	0,51	deleterious	0,5	neutral	-3	deleterious	0,53	medium_impact	-0,89	medium_impact	0,27	medium_impact	0,03	0,74	0,85	46,46	7,68	N	0,31	N	0,58	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14234	14234	T	C	MI.23274	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	440	147	D	G	gAt/gGt	2,69	0,8	0	possibly_damaging	0,56	neutral	0,45	neutral	2,34	deleterious	-4,54	neutral	-0,58	neutral_impact	0,64	neutral	0,9	neutral	0,91	deleterious	2,71	20,8	0,38	0,5	neutral	0,34	disease	0,7	neutral	0,49	disease	0,57	1	neutral	0,57	neutral	0,45	neutral	-3	deleterious	0,57	medium_impact	-0,89	medium_impact	0,16	medium_impact	-0,6	0,77	0,85	46,46	7,68	N	0,41	N	0,51	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14234	14234	T	A	MI.23275	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	440	147	D	V	gAt/gTt	2,69	0,8	0	probably_damaging	0,92	neutral	0,54	neutral	2,3	deleterious	-5,43	deleterious	-2,99	medium_impact	1,95	neutral	0,8	neutral	0,74	deleterious	4,41	24,1	0,36	0,5	neutral	0,47	disease	0,85	disease	0,63	disease	0,64	3	neutral	0,91	neutral	0,31	deleterious	1	deleterious	0,77	low_impact	-1,77	medium_impact	0,25	medium_impact	0,49	0,7	0,85	46,46	7,68	N	0,32	N	0,86	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14235	14235	C	A	MI.23276	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	439	147	D	Y	Gat/Tat	-1,67	0	0	probably_damaging	0,97	neutral	1	neutral	2,31	deleterious	-6,33	deleterious	-2,87	low_impact	1,4	neutral	0,86	neutral	0,78	deleterious	4,62	24,5	0,36	0,5	disease	0,63	disease	0,83	disease	0,54	disease	0,64	3	neutral	0,97	deleterious	0,52	neutral	-2	deleterious	0,83	low_impact	-2,18	high_impact	1,87	medium_impact	0,03	0,6	0,8	46,46	7,68	N	0,22	N	0,86	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14235	14235	C	T	MI.23277	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	439	147	D	N	Gat/Aat	-1,67	0	0	benign	0,06	neutral	0,3	neutral	2,35	deleterious	-4,05	neutral	0,84	neutral_impact	0,66	neutral	0,9	neutral	0,82	deleterious	3,27	22,8	0,69	0,75	neutral	0,28	disease	0,73	neutral	0,39	disease	0,58	2	neutral	0,67	deleterious	0,62	neutral	-6	neutral	0,22	medium_impact	0,3	medium_impact	0	medium_impact	-0,59	0,9	0,95	46,46	7,68	N	0,41	N	0,52	NA	NA	0,18	.	.	.	.	.	.	COSM1138252	.	.	.	.	.	.	.	.
chrM	14235	14235	C	G	MI.23278	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	439	147	D	H	Gat/Cat	-1,67	0	0	probably_damaging	0,97	neutral	0,46	neutral	2,27	deleterious	-5,64	neutral	-1,52	medium_impact	1,95	neutral	0,79	neutral	0,62	deleterious	3,97	23,6	0,46	0,55	disease	0,5	disease	0,69	disease	0,65	disease	0,74	5	neutral	0,97	neutral	0,25	deleterious	1	deleterious	0,76	low_impact	-2,18	medium_impact	0,17	medium_impact	0,49	0,79	0,85	46,46	7,68	N	0,27	N	0,68	NA	NA	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14237	14237	T	G	MI.23279	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	437	146	Y	S	tAt/tCt	-0,29	0	0	probably_damaging	1	neutral	0,43	neutral	1,91	deleterious	-4,84	deleterious	-8,98	high_impact	3,63	neutral	0,63	damaging	0,08	deleterious	4,14	23,8	0,18	0,45	disease	0,79	disease	0,95	disease	0,79	disease	0,91	8	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	0,14	medium_impact	1,9	0,49	0,8	50	8,58	N	0,4	N	0,96	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6112	6112	T	C	MI.2328	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	209	70	V	A	gTa/gCa	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,8	neutral	-0,04	deleterious	-2,53	medium_impact	2,62	damaging	0,57	neutral	0,59	deleterious	3,45	23	0,35	0,55	neutral	0,27	disease	0,61	disease	0,59	disease	0,66	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,71	low_impact	-3,58	low_impact	-1,48	medium_impact	1,32	0,32	0,9	2,14	6,63	P	0,53	P	0,47	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14237	14237	T	C	MI.23280	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	437	146	Y	C	tAt/tGt	-0,29	0	0	probably_damaging	1	neutral	0,18	neutral	1,86	deleterious	-6,77	deleterious	-8,98	high_impact	3,98	damaging	0,44	damaging	0,03	deleterious	3,52	23,1	0,22	0,45	disease	0,91	disease	0,95	disease	0,84	disease	0,92	8	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,93	low_impact	-3,55	medium_impact	-0,16	high_impact	2,19	0,42	0,8	50	8,58	N	0,5	N	1	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14237	14237	T	A	MI.23281	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	437	146	Y	F	tAt/tTt	-0,29	0	0	probably_damaging	1	neutral	0,56	neutral	2	neutral	-2,93	deleterious	-3,99	medium_impact	2,65	neutral	0,69	damaging	0,17	deleterious	3,85	23,4	0,27	0,45	neutral	0,44	disease	0,9	disease	0,75	disease	0,66	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,87	low_impact	-3,55	medium_impact	0,27	medium_impact	1,08	0,69	0,85	50	8,58	N	0,28	N	0,8	NA	NA	0,61	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14238	14238	A	T	MI.23282	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	436	146	Y	N	Tat/Aat	2,92	0,98	0	probably_damaging	1	neutral	0,29	neutral	1,86	deleterious	-5,32	deleterious	-8,98	high_impact	3,98	damaging	0,51	damaging	0,06	deleterious	3,76	23,3	0,18	0,45	disease	0,83	disease	0,96	disease	0,8	disease	0,92	8	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	-0,01	high_impact	2,19	0,51	0,8	50	8,58	P	0,64	P	1	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14238	14238	A	C	MI.23283	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	436	146	Y	D	Tat/Gat	2,92	0,98	0	probably_damaging	1	neutral	0,16	neutral	1,86	deleterious	-5,53	deleterious	-9,97	high_impact	3,98	damaging	0,49	damaging	0,04	deleterious	3,77	23,4	0,12	0,4	disease	0,86	disease	0,96	disease	0,84	disease	0,92	8	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	-0,19	high_impact	2,19	0,46	0,8	50	8,58	P	0,62	P	0,97	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14238	14238	A	G	MI.23284	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	436	146	Y	H	Tat/Cat	2,92	0,98	0	probably_damaging	1	neutral	0,37	neutral	1,85	deleterious	-5,03	deleterious	-4,99	high_impact	3,98	damaging	0,56	damaging	0,05	deleterious	3,77	23,4	0,24	0,45	disease	0,75	disease	0,93	disease	0,84	disease	0,89	8	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,91	low_impact	-3,55	medium_impact	0,08	high_impact	2,19	0,59	0,8	50	8,58	P	0,59	P	0,98	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14239	14239	C	G	MI.23285	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	435	145	L	F	ttG/ttC	4,98	0,99	0	probably_damaging	1	neutral	0,45	neutral	1,79	neutral	-2,83	deleterious	-3,65	medium_impact	2,25	neutral	0,8	neutral	0,29	deleterious	3,87	23,5	0,33	0,5	neutral	0,31	neutral	0,49	neutral	0,47	neutral	0,48	0	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,74	low_impact	-3,55	medium_impact	0,16	medium_impact	0,75	0,74	0,85	49,12	8,84	P	0,55	P	0,69	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14239	14239	C	A	MI.23286	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	435	145	L	F	ttG/ttT	4,98	0,99	0	probably_damaging	1	neutral	0,45	neutral	1,79	neutral	-2,83	deleterious	-3,65	medium_impact	2,25	neutral	0,8	neutral	0,29	deleterious	4,16	23,8	0,33	0,5	neutral	0,31	neutral	0,49	neutral	0,47	neutral	0,48	0	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,74	low_impact	-3,55	medium_impact	0,16	medium_impact	0,75	0,74	0,85	49,12	8,84	P	0,54	P	0,69	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14240	14240	A	C	MI.23287	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	434	145	L	W	tTg/tGg	-6,02	0	0	probably_damaging	1	neutral	0,14	neutral	1,64	deleterious	-6,43	deleterious	-5,69	high_impact	3,7	neutral	0,75	damaging	0,08	deleterious	3,37	22,9	0,11	0,4	disease	0,85	disease	0,87	disease	0,64	disease	0,8	6	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,23	medium_impact	1,96	0,54	0,8	49,12	8,84	N	0,29	N	0,9	NA	NA	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14240	14240	A	G	MI.23288	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	434	145	L	S	tTg/tCg	-6,02	0	0	probably_damaging	1	neutral	0,22	neutral	1,68	deleterious	-4,62	deleterious	-5,58	high_impact	3,7	neutral	0,75	damaging	0,12	deleterious	3,74	23,3	0,12	0,4	disease	0,71	disease	0,82	disease	0,68	disease	0,77	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,1	medium_impact	1,96	0,55	0,8	49,12	8,84	N	0,34	N	0,88	NA	NA	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14241	14241	A	C	MI.23289	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	433	145	L	V	Ttg/Gtg	6,59	0,8	0	probably_damaging	1	neutral	0,52	neutral	1,73	neutral	-2,08	neutral	-2,44	medium_impact	2,46	neutral	0,77	damaging	0,23	deleterious	3,26	22,8	0,3	0,45	neutral	0,35	disease	0,68	neutral	0,5	disease	0,53	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,76	low_impact	-3,55	medium_impact	0,23	medium_impact	0,92	0,76	0,85	49,12	8,84	N	0,36	N	0,55	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6114	6114	A	C	MI.2329	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	211	71	M	L	Ata/Cta	-13,29	0	0	probably_damaging	0,95	deleterious	0	neutral	2,75	neutral	-0,89	neutral	-1,86	high_impact	4,75	damaging	0,52	damaging	0,12	deleterious	3,19	22,7	0,47	0,55	neutral	0,36	disease	0,84	disease	0,6	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,75	low_impact	-1,96	low_impact	-1,48	high_impact	3,29	0,54	0,9	1,95	6,89	P	0,61	P	0,61	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14241	14241	A	T	MI.23290	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	433	145	L	M	Ttg/Atg	6,59	0,8	0	probably_damaging	1	neutral	0,31	neutral	1,71	neutral	-1,78	neutral	-1,57	low_impact	1,22	neutral	0,81	neutral	0,91	deleterious	2,3	18,16	0,24	0,45	neutral	0,16	neutral	0,1	neutral	0,3	neutral	0,28	4	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,68	low_impact	-3,55	medium_impact	0,01	medium_impact	-0,12	0,72	0,85	49,12	8,84	N	0,51	P	0,23	NA	NA	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14243	14243	G	C	MI.23291	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	431	144	A	G	gCt/gGt	-6,02	0	0	probably_damaging	1	neutral	0,23	neutral	2,25	deleterious	-3,95	deleterious	-3,13	medium_impact	2	neutral	0,87	neutral	0,74	deleterious	2,72	20,9	0,22	0,45	disease	0,52	neutral	0,41	neutral	0,41	neutral	0,35	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,76	low_impact	-3,55	medium_impact	-0,09	medium_impact	0,54	0,86	0,9	49,12	8,59	N	0,46	N	0,62	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14243	14243	G	A	MI.23292	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	431	144	A	V	gCt/gTt	-6,02	0	0	probably_damaging	1	neutral	0,42	neutral	2,36	deleterious	-3,77	deleterious	-3,61	low_impact	1,7	neutral	0,72	neutral	0,44	deleterious	4,4	24,1	0,33	0,5	neutral	0,15	neutral	0,39	neutral	0,31	neutral	0,45	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,69	low_impact	-3,55	medium_impact	0,13	medium_impact	0,28	0,93	0,95	49,12	8,59	N	0,32	N	0,71	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14243	14243	G	T	MI.23293	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	431	144	A	D	gCt/gAt	-6,02	0	0	probably_damaging	1	neutral	0,08	neutral	2,25	deleterious	-4,72	deleterious	-4,78	medium_impact	2,74	neutral	0,81	damaging	0,14	deleterious	4,17	23,8	0,19	0,45	disease	0,59	disease	0,78	disease	0,58	disease	0,77	5	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,84	low_impact	-3,55	medium_impact	-0,38	medium_impact	1,16	0,81	0,85	49,12	8,59	N	0,35	N	0,93	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14244	14244	C	G	MI.23294	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	430	144	A	P	Gct/Cct	1,77	0	0	probably_damaging	1	neutral	0,08	neutral	2,24	deleterious	-5,07	deleterious	-4,26	medium_impact	2,94	neutral	0,77	damaging	0,08	deleterious	4,26	23,9	0,13	0,4	disease	0,6	disease	0,83	neutral	0,42	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,87	low_impact	-3,55	medium_impact	-0,38	medium_impact	1,32	0,9	0,95	49,12	8,59	N	0,31	N	0,9	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14244	14244	C	T	MI.23295	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	430	144	A	T	Gct/Act	1,77	0	0	probably_damaging	1	neutral	0,23	neutral	2,29	deleterious	-3,67	deleterious	-3,06	medium_impact	2,6	neutral	0,8	damaging	0,27	deleterious	4,58	24,4	0,43	0,55	neutral	0,34	neutral	0,39	neutral	0,42	neutral	0,47	1	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,71	low_impact	-3,55	medium_impact	-0,09	medium_impact	1,04	0,94	0,95	49,12	8,59	N	0,38	N	0,76	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14244	14244	C	A	MI.23296	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	430	144	A	S	Gct/Tct	1,77	0	0	probably_damaging	1	neutral	0,32	neutral	2,31	deleterious	-3,23	neutral	-1,7	low_impact	1,47	neutral	0,83	neutral	0,82	deleterious	3,11	22,5	0,44	0,55	neutral	0,37	neutral	0,37	neutral	0,26	neutral	0,46	1	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,75	low_impact	-3,55	medium_impact	0,03	medium_impact	0,09	0,88	0,9	49,12	8,59	N	0,42	N	0,6	NA	NA	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14246	14246	C	G	MI.23297	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	428	143	G	A	gGg/gCg	-7,62	0	0	benign	0,15	neutral	0,46	neutral	2,35	deleterious	-4,4	neutral	1,79	neutral_impact	-0,15	neutral	0,9	neutral	0,92	deleterious	0,82	9,58	0,27	0,45	neutral	0,14	neutral	0,18	neutral	0,16	neutral	0,27	5	neutral	0,46	deleterious	0,66	neutral	-6	neutral	0,18	medium_impact	-0,11	medium_impact	0,17	low_impact	-1,27	0,51	0,8	19,47	13,18	N	0,45	N	0,27	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14246	14246	C	A	MI.23298	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	428	143	G	V	gGg/gTg	-7,62	0	0	possibly_damaging	0,85	neutral	0,68	neutral	2,32	deleterious	-5,73	neutral	-1,82	low_impact	1,84	neutral	0,7	neutral	0,67	deleterious	4,37	24,1	0,22	0,45	neutral	0,38	disease	0,82	disease	0,6	disease	0,76	5	neutral	0,82	neutral	0,42	neutral	-3	deleterious	0,76	low_impact	-1,49	medium_impact	0,39	medium_impact	0,4	0,63	0,8	19,47	13,18	N	0,27	N	0,73	NA	NA	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14246	14246	C	T	MI.23299	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	428	143	G	E	gGg/gAg	-7,62	0	0	possibly_damaging	0,89	neutral	0,22	neutral	2,33	deleterious	-5,32	neutral	-2,03	medium_impact	2,93	neutral	0,73	neutral	0,56	deleterious	4,34	24	0,2	0,45	neutral	0,42	disease	0,86	disease	0,69	disease	0,81	6	neutral	0,92	neutral	0,17	NA	0	deleterious	0,8	low_impact	-1,63	medium_impact	-0,1	medium_impact	1,31	0,68	0,85	19,47	13,18	N	0,37	N	0,8	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8636	8636	T	G	MI.233	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	110	37	L	R	cTc/cGc	0,59	0,38	0	probably_damaging	0,91	neutral	0,05	neutral	4,34	neutral	-2,99	deleterious	-2,52	medium_impact	2,51	neutral	0,82	neutral	0,44	deleterious	3,96	23,6	0,36	0,65	disease	0,73	disease	0,82	disease	0,76	disease	0,81	6	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,82	low_impact	-1,71	medium_impact	-0,43	medium_impact	1,05	0,56	0,9	20,35	20,89	N	0,27	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6114	6114	A	T	MI.2330	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	211	71	M	L	Ata/Tta	-13,29	0	0	probably_damaging	0,95	deleterious	0	neutral	2,75	neutral	-0,89	neutral	-1,86	high_impact	4,75	damaging	0,52	damaging	0,12	deleterious	3,28	22,8	0,47	0,55	neutral	0,36	disease	0,84	disease	0,6	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,75	low_impact	-1,96	low_impact	-1,48	high_impact	3,29	0,54	0,9	1,95	6,89	P	0,61	P	0,61	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14247	14247	C	A	MI.23300	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	427	143	G	W	Ggg/Tgg	3,15	0,34	0	probably_damaging	0,99	neutral	0,11	neutral	2,26	deleterious	-8,54	deleterious	-3,81	medium_impact	2,93	neutral	0,73	neutral	0,5	deleterious	4,99	25,1	0,14	0,4	disease	0,86	disease	0,91	disease	0,65	disease	0,83	6	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,87	low_impact	-2,63	medium_impact	-0,3	medium_impact	1,31	0,61	0,8	19,47	13,18	N	0,4	N	0,84	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14247	14247	C	G	MI.23301	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	427	143	G	R	Ggg/Cgg	3,15	0,34	0	probably_damaging	0,96	neutral	0,23	neutral	2,32	deleterious	-5,95	neutral	-2,18	medium_impact	2,93	neutral	0,71	neutral	0,49	deleterious	4,34	24	0,18	0,45	neutral	0,49	disease	0,88	disease	0,71	disease	0,82	6	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,84	low_impact	-2,06	medium_impact	-0,09	medium_impact	1,31	0,8	0,85	19,47	13,18	N	0,45	N	0,75	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14249	14249	G	A	MI.23302	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	425	142	A	V	gCg/gTg	-5,56	0	0,01	benign	0,36	neutral	0,57	neutral	2,78	deleterious	-3,77	neutral	2,07	neutral_impact	-0,52	neutral	0,87	neutral	0,96	neutral	1,59	13,81	0,24	0,45	neutral	0,15	neutral	0,1	neutral	0,23	neutral	0,26	5	neutral	0,36	deleterious	0,61	neutral	-6	deleterious	0,45	medium_impact	-0,57	medium_impact	0,27	low_impact	-1,58	0,78	0,85	11,95	13,75	N	0,31	N	0,25	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14249	14249	G	T	MI.23303	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	425	142	A	E	gCg/gAg	-5,56	0	0,01	probably_damaging	0,99	neutral	0,27	neutral	2,23	deleterious	-4,42	neutral	-2,37	medium_impact	2,67	neutral	0,77	neutral	0,6	deleterious	4,12	23,8	0,11	0,4	disease	0,52	disease	0,83	disease	0,66	disease	0,8	6	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,84	low_impact	-2,63	medium_impact	-0,03	medium_impact	1,1	0,84	0,9	11,95	13,75	N	0,3	N	0,81	NA	NA	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14249	14249	G	C	MI.23304	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	425	142	A	G	gCg/gGg	-5,56	0	0,01	probably_damaging	0,95	neutral	0,43	neutral	2,24	deleterious	-3,95	neutral	-2,19	low_impact	1,57	neutral	0,87	neutral	0,93	deleterious	2,65	20,5	0,11	0,4	disease	0,52	disease	0,57	neutral	0,47	neutral	0,48	0	neutral	0,94	neutral	0,24	neutral	-2	deleterious	0,76	low_impact	-1,97	medium_impact	0,14	medium_impact	0,18	0,75	0,85	11,95	13,75	N	0,38	N	0,61	NA	NA	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14250	14250	C	A	MI.23305	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	424	142	A	S	Gcg/Tcg	2	0,01	0	probably_damaging	0,95	neutral	0,43	neutral	2,25	deleterious	-3,23	neutral	-1,72	low_impact	1,86	neutral	0,82	neutral	0,73	deleterious	3,14	22,6	0,25	0,45	neutral	0,38	disease	0,55	neutral	0,31	disease	0,53	1	neutral	0,94	neutral	0,24	neutral	-2	deleterious	0,75	low_impact	-1,97	medium_impact	0,14	medium_impact	0,42	0,93	0,95	11,95	13,75	N	0,37	N	0,58	NA	NA	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14250	14250	C	G	MI.23306	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	424	142	A	P	Gcg/Ccg	2	0,01	0	probably_damaging	0,99	neutral	0,2	neutral	2,21	deleterious	-5,07	neutral	-2,37	medium_impact	2,67	neutral	0,76	neutral	0,43	deleterious	4,17	23,8	0,09	0,35	disease	0,6	disease	0,89	neutral	0,49	disease	0,79	6	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,88	low_impact	-2,63	medium_impact	-0,13	medium_impact	1,1	0,88	0,9	11,95	13,75	N	0,39	N	0,79	NA	NA	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14250	14250	C	T	MI.23307	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	424	142	A	T	Gcg/Acg	2	0,01	0	probably_damaging	0,94	neutral	0,42	neutral	2,27	deleterious	-3,67	neutral	-0,58	low_impact	1,63	neutral	0,78	neutral	0,72	deleterious	3,53	23,1	0,32	0,5	neutral	0,31	disease	0,51	neutral	0,33	disease	0,52	0	neutral	0,94	neutral	0,24	neutral	-2	deleterious	0,69	low_impact	-1,89	medium_impact	0,13	medium_impact	0,23	0,79	0,85	11,95	13,75	N	0,38	N	0,52	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14252	14252	C	T	MI.23308	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	422	141	G	D	gGt/gAt	-3,5	0	0	probably_damaging	1	neutral	0,21	neutral	1,1	deleterious	-6,61	deleterious	-6,98	high_impact	4	damaging	0,52	damaging	0,04	deleterious	4,24	23,9	0,18	0,45	disease	0,83	disease	0,93	disease	0,86	disease	0,91	8	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,91	low_impact	-3,55	medium_impact	-0,11	high_impact	2,21	0,56	0,8	46,46	8,22	N	0,38	N	0,96	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14252	14252	C	G	MI.23309	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	422	141	G	A	gGt/gCt	-3,5	0	0	probably_damaging	1	neutral	0,51	neutral	1,17	deleterious	-5,51	deleterious	-5,98	high_impact	3,65	neutral	0,63	damaging	0,09	deleterious	3,5	23,1	0,28	0,45	disease	0,7	disease	0,84	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-3,55	medium_impact	0,22	medium_impact	1,92	0,8	0,85	46,46	8,22	N	0,27	N	0,78	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6114	6114	A	G	MI.2331	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	211	71	M	V	Ata/Gta	-13,29	0	0	probably_damaging	0,97	deleterious	0	neutral	2,76	neutral	-0,6	deleterious	-2,54	high_impact	3,82	damaging	0,55	damaging	0,09	deleterious	2,69	20,7	0,47	0,55	neutral	0,24	disease	0,91	disease	0,63	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,79	low_impact	-2,18	low_impact	-1,48	high_impact	2,43	0,59	0,9	1,95	6,89	N	0,26	N	0,88	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14252	14252	C	A	MI.23310	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	422	141	G	V	gGt/gTt	-3,5	0	0	probably_damaging	1	neutral	0,51	neutral	1,1	deleterious	-6,92	deleterious	-8,97	high_impact	4	damaging	0,39	damaging	0,04	deleterious	4,38	24,1	0,16	0,45	disease	0,86	disease	0,93	disease	0,8	disease	0,91	8	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,91	low_impact	-3,55	medium_impact	0,22	high_impact	2,21	0,7	0,85	46,46	8,22	P	0,57	P	0,98	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14253	14253	C	A	MI.23311	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	421	141	G	C	Ggt/Tgt	2	0,44	0	probably_damaging	1	neutral	0,18	neutral	1,08	deleterious	-8,06	deleterious	-8,78	high_impact	4	damaging	0,46	damaging	0,03	deleterious	4,77	24,7	0,15	0,4	disease	0,91	disease	0,92	disease	0,8	disease	0,89	8	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,55	medium_impact	-0,16	high_impact	2,21	0,64	0,8	46,46	8,22	N	0,51	P	0,97	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14253	14253	C	T	MI.23312	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	421	141	G	S	Ggt/Agt	2	0,44	0	probably_damaging	1	neutral	0,41	neutral	1,15	deleterious	-5,78	deleterious	-5,98	medium_impact	3,31	damaging	0,57	damaging	0,06	deleterious	4,48	24,2	0,26	0,45	disease	0,73	disease	0,89	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,88	low_impact	-3,55	medium_impact	0,12	medium_impact	1,63	0,75	0,85	46,46	8,22	N	0,32	N	1	NA	NA	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14253	14253	C	G	MI.23313	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	421	141	G	R	Ggt/Cgt	2	0,44	0	probably_damaging	1	neutral	0,35	neutral	1,09	deleterious	-7,13	deleterious	-7,98	high_impact	4	damaging	0,48	damaging	0,04	deleterious	4,23	23,9	0,17	0,45	disease	0,87	disease	0,91	disease	0,87	disease	0,9	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	0,06	high_impact	2,21	0,77	0,85	46,46	8,22	P	0,52	P	1	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14254	14254	A	C	MI.23314	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	420	140	I	M	atT/atG	3,15	0,46	0	probably_damaging	0,94	neutral	0,24	neutral	2,29	deleterious	-4,19	neutral	0,61	neutral_impact	0,59	neutral	0,87	neutral	0,93	deleterious	0,66	8,53	0,38	0,5	neutral	0,15	neutral	0,26	neutral	0,18	neutral	0,43	1	neutral	0,96	neutral	0,15	neutral	-2	deleterious	0,62	low_impact	-1,89	medium_impact	-0,07	medium_impact	-0,65	0,79	0,85	44,25	8,21	N	0,5	N	0,18	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14254	14254	A	T	MI.23315	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	420	140	I	M	atT/atA	3,15	0,46	0	probably_damaging	0,94	neutral	0,24	neutral	2,29	deleterious	-4,19	neutral	0,61	neutral_impact	0,59	neutral	0,87	neutral	0,93	deleterious	0,75	9,15	0,38	0,5	neutral	0,15	neutral	0,26	neutral	0,18	neutral	0,43	1	neutral	0,96	neutral	0,15	neutral	-2	deleterious	0,62	low_impact	-1,89	medium_impact	-0,07	medium_impact	-0,65	0,79	0,85	44,25	8,21	P	0,51	P	0,18	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14255	14255	A	G	MI.23316	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	419	140	I	T	aTt/aCt	-2,81	0	0	benign	0,03	neutral	0,48	neutral	2,31	deleterious	-4,26	neutral	-0,96	neutral_impact	0,7	neutral	0,91	neutral	0,84	neutral	1,64	14,06	0,33	0,5	neutral	0,23	neutral	0,42	neutral	0,36	neutral	0,44	1	neutral	0,49	deleterious	0,73	neutral	-6	neutral	0,14	medium_impact	0,59	medium_impact	0,19	medium_impact	-0,55	0,56	0,8	44,25	8,21	N	0,46	N	0,52	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14255	14255	A	C	MI.23317	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	419	140	I	S	aTt/aGt	-2,81	0	0	benign	0,39	neutral	0,52	neutral	2,41	deleterious	-4,68	neutral	-1,59	neutral_impact	0,24	neutral	0,86	neutral	0,97	deleterious	2,14	17,14	0,3	0,45	neutral	0,15	neutral	0,25	neutral	0,22	neutral	0,42	2	neutral	0,42	deleterious	0,57	neutral	-6	neutral	0,39	medium_impact	-0,62	medium_impact	0,23	medium_impact	-0,94	0,53	0,8	44,25	8,21	N	0,37	N	0,49	NA	NA	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14255	14255	A	T	MI.23318	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	419	140	I	N	aTt/aAt	-2,81	0	0	possibly_damaging	0,77	neutral	0,38	neutral	2,27	deleterious	-5,64	deleterious	-3,06	low_impact	1,32	neutral	0,84	neutral	0,8	deleterious	2,74	21	0,35	0,5	neutral	0,35	disease	0,75	neutral	0,37	disease	0,57	1	neutral	0,79	neutral	0,31	neutral	-3	deleterious	0,69	low_impact	-1,28	medium_impact	0,09	medium_impact	-0,03	0,46	0,8	44,25	8,21	N	0,37	N	0,81	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14256	14256	T	C	MI.23319	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	418	140	I	V	Att/Gtt	-0,75	0	0	benign	0,28	neutral	0,55	neutral	2,36	neutral	-1,8	neutral	0,33	neutral_impact	0,28	neutral	0,88	neutral	0,94	neutral	-1,17	0,01	0,35	0,5	neutral	0,13	neutral	0,21	neutral	0,2	neutral	0,36	3	neutral	0,35	deleterious	0,64	neutral	-6	neutral	0,28	medium_impact	-0,42	medium_impact	0,26	medium_impact	-0,91	0,54	0,8	44,25	8,21	N	0,38	N	0,56	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6115	6115	T	C	MI.2332	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	212	71	M	T	aTa/aCa	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,74	neutral	0,28	deleterious	-3,84	medium_impact	3,01	damaging	0,55	damaging	0,13	deleterious	2,9	21,9	0,31	0,55	neutral	0,31	disease	0,89	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,86	low_impact	-2,64	low_impact	-1,48	medium_impact	1,68	0,38	0,9	1,95	6,89	N	0,41	N	0,79	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14256	14256	T	A	MI.23320	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	418	140	I	F	Att/Ttt	-0,75	0	0	possibly_damaging	0,87	neutral	0,71	neutral	2,27	deleterious	-4,31	neutral	-1,88	low_impact	1,56	neutral	0,72	neutral	0,41	deleterious	3,03	22,3	0,35	0,5	neutral	0,31	disease	0,61	neutral	0,34	disease	0,53	1	neutral	0,85	neutral	0,42	neutral	-3	deleterious	0,67	low_impact	-1,55	medium_impact	0,42	medium_impact	0,17	0,77	0,85	44,25	8,21	N	0,34	N	0,52	NA	NA	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14256	14256	T	G	MI.23321	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	418	140	I	L	Att/Ctt	-0,75	0	0	benign	0,28	neutral	0,7	neutral	2,36	neutral	-2,08	neutral	-0,12	low_impact	1,05	neutral	0,84	neutral	0,74	deleterious	0,88	9,96	0,3	0,45	neutral	0,16	neutral	0,45	neutral	0,31	neutral	0,46	1	neutral	0,22	deleterious	0,71	neutral	-6	neutral	0,37	medium_impact	-0,42	medium_impact	0,41	medium_impact	-0,26	0,73	0,85	44,25	8,21	N	0,28	N	0,56	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14258	14258	G	A	MI.23322	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	416	139	P	L	cCt/cTt	-1,44	0	0	benign	0,37	neutral	0,68	neutral	2,47	deleterious	-5,32	neutral	-0,82	neutral_impact	0,32	neutral	0,79	neutral	0,72	deleterious	0,29	5,6	0,44	0,55	neutral	0,09	neutral	0,28	neutral	0,36	neutral	0,41	2	neutral	0,29	deleterious	0,66	neutral	-6	neutral	0,28	medium_impact	-0,58	medium_impact	0,39	medium_impact	-0,87	0,91	0,95	48,23	8,84	N	0,31	N	0,72	NA	NA	0,17	rs202227543	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14258	14258	G	C	MI.23323	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	416	139	P	R	cCt/cGt	-1,44	0	0	possibly_damaging	0,7	neutral	0,34	neutral	2,32	deleterious	-5,5	neutral	-1,26	low_impact	1,84	neutral	0,83	neutral	0,51	deleterious	0,07	3,34	0,36	0,5	neutral	0,23	neutral	0,36	neutral	0,46	neutral	0,45	1	neutral	0,74	neutral	0,32	neutral	-3	deleterious	0,52	low_impact	-1,13	medium_impact	0,05	medium_impact	0,4	0,72	0,85	48,23	8,84	N	0,42	N	0,68	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14258	14258	G	T	MI.23324	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	416	139	P	H	cCt/cAt	-1,44	0	0	possibly_damaging	0,9	neutral	0,53	neutral	2,31	deleterious	-6,63	neutral	-1,07	low_impact	1,5	neutral	0,81	neutral	0,52	neutral	1,47	13,14	0,38	0,5	neutral	0,32	neutral	0,21	neutral	0,41	neutral	0,37	3	neutral	0,88	neutral	0,32	neutral	-3	deleterious	0,61	low_impact	-1,67	medium_impact	0,24	medium_impact	0,12	0,72	0,85	48,23	8,84	N	0,37	N	0,71	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14259	14259	G	T	MI.23325	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	415	139	P	T	Cct/Act	-0,52	0	0	benign	0,02	neutral	0,39	neutral	2,39	deleterious	-5,02	neutral	0,18	neutral_impact	0,74	neutral	0,9	neutral	0,85	neutral	-0,24	0,89	0,37	0,5	neutral	0,14	neutral	0,12	neutral	0,18	neutral	0,31	4	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,08	medium_impact	0,75	medium_impact	0,1	medium_impact	-0,52	0,76	0,85	48,23	8,84	N	0,56	P	0,45	NA	NA	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14259	14259	G	C	MI.23326	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	415	139	P	A	Cct/Gct	-0,52	0	0	benign	0,18	neutral	0,51	neutral	2,42	deleterious	-4,34	neutral	1,11	neutral_impact	0,26	neutral	0,9	neutral	0,98	neutral	-0,94	0,02	0,37	0,5	neutral	0,1	neutral	0,12	neutral	0,33	neutral	0,3	4	neutral	0,39	deleterious	0,67	neutral	-6	neutral	0,18	medium_impact	-0,19	medium_impact	0,22	medium_impact	-0,92	0,68	0,85	48,23	8,84	N	0,46	N	0,22	NA	NA	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14259	14259	G	A	MI.23327	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	415	139	P	S	Cct/Tct	-0,52	0	0	benign	0,01	neutral	0,41	neutral	2,37	deleterious	-4,6	neutral	0,9	neutral_impact	-0,8	neutral	0,96	neutral	0,96	deleterious	0	2,62	0,5	0,6	neutral	0,16	neutral	0,13	neutral	0,17	neutral	0,3	4	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,1	medium_impact	1,03	medium_impact	0,12	low_impact	-1,81	0,4	0,8	48,23	8,84	N	0,49	N	0,22	NA	NA	0,15	.	.	.	.	.	.	COSM1133872	.	.	.	.	.	.	.	.
chrM	14260	14260	A	C	MI.23328	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	414	138	D	E	gaT/gaG	-1,89	0	0	probably_damaging	1	neutral	0,48	neutral	1,88	deleterious	-3,18	neutral	-0,93	low_impact	1,82	neutral	0,88	neutral	0,86	neutral	1,64	14,09	0,56	0,6	neutral	0,16	disease	0,69	neutral	0,44	neutral	0,5	0	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,73	low_impact	-3,55	medium_impact	0,19	medium_impact	0,39	0,75	0,85	44,69	8,06	N	0,33	N	0,19	NA	NA	0,28	rs386829207	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14260	14260	A	T	MI.23329	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	414	138	D	E	gaT/gaA	-1,89	0	0	probably_damaging	1	neutral	0,48	neutral	1,88	deleterious	-3,18	neutral	-0,93	low_impact	1,82	neutral	0,88	neutral	0,86	neutral	1,75	14,72	0,56	0,6	neutral	0,16	disease	0,69	neutral	0,44	neutral	0,5	0	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,73	low_impact	-3,55	medium_impact	0,19	medium_impact	0,39	0,75	0,85	44,69	8,06	N	0,32	N	0,19	NA	NA	0,28	rs386829207	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6115	6115	T	A	MI.2333	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	212	71	M	K	aTa/aAa	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,61	neutral	-2,71	deleterious	-3,85	high_impact	5,1	damaging	0,55	damaging	0,07	deleterious	4,02	23,6	0,17	0,55	disease	0,67	disease	0,94	disease	0,74	disease	0,88	8	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,64	low_impact	-1,48	high_impact	3,61	0,47	0,9	1,95	6,89	P	0,73	P	0,93	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14261	14261	T	G	MI.23330	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	413	138	D	A	gAt/gCt	-0,29	0	0	probably_damaging	1	neutral	0,66	neutral	1,73	deleterious	-4,27	deleterious	-5,03	high_impact	3,83	neutral	0,65	damaging	0,25	deleterious	4,08	23,7	0,39	0,5	neutral	0,46	disease	0,91	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,84	low_impact	-3,55	medium_impact	0,37	high_impact	2,07	0,75	0,85	44,69	8,06	N	0,4	N	0,83	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14261	14261	T	C	MI.23331	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	413	138	D	G	gAt/gGt	-0,29	0	0	probably_damaging	1	neutral	0,42	neutral	1,73	deleterious	-4,54	deleterious	-4,35	medium_impact	2,48	neutral	0,76	neutral	0,8	deleterious	2,58	19,99	0,32	0,5	neutral	0,28	disease	0,89	disease	0,75	disease	0,78	6	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,78	low_impact	-3,55	medium_impact	0,13	medium_impact	0,94	0,73	0,85	44,69	8,06	N	0,41	N	0,29	NA	NA	0,57	.	.	.	.	.	.	COSM1155549	.	.	.	.	.	.	.	.
chrM	14261	14261	T	A	MI.23332	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	413	138	D	V	gAt/gTt	-0,29	0	0	probably_damaging	1	neutral	0,56	neutral	1,69	deleterious	-5,43	deleterious	-6,23	medium_impact	3,48	neutral	0,62	damaging	0,2	deleterious	4,25	23,9	0,31	0,45	disease	0,69	disease	0,95	disease	0,78	disease	0,9	8	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,87	low_impact	-3,55	medium_impact	0,27	medium_impact	1,78	0,64	0,8	44,69	8,06	N	0,37	N	0,9	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14262	14262	C	T	MI.23333	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	412	138	D	N	Gat/Aat	1,77	0,85	0	probably_damaging	1	neutral	0,42	neutral	1,75	deleterious	-4,05	deleterious	-3,13	medium_impact	3,28	neutral	0,64	damaging	0,2	deleterious	4,59	24,4	0,65	0,7	neutral	0,38	disease	0,89	disease	0,7	disease	0,77	5	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,8	low_impact	-3,55	medium_impact	0,13	medium_impact	1,61	0,87	0,9	44,69	8,06	N	0,41	N	0,61	NA	NA	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14262	14262	C	G	MI.23334	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	412	138	D	H	Gat/Cat	1,77	0,85	0	probably_damaging	1	neutral	0,55	neutral	1,69	deleterious	-5,64	deleterious	-4,33	high_impact	3,83	neutral	0,66	damaging	0,18	deleterious	4	23,6	0,38	0,5	disease	0,63	disease	0,89	disease	0,81	disease	0,84	7	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	0,26	high_impact	2,07	0,73	0,85	44,69	8,06	N	0,48	N	0,79	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14262	14262	C	A	MI.23335	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	412	138	D	Y	Gat/Tat	1,77	0,85	0	probably_damaging	1	neutral	1	neutral	1,68	deleterious	-6,33	deleterious	-6,19	high_impact	3,83	neutral	0,72	neutral	0,31	deleterious	4,62	24,5	0,34	0,5	disease	0,78	disease	0,94	disease	0,81	disease	0,73	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,89	low_impact	-3,55	high_impact	1,87	high_impact	2,07	0,56	0,8	44,69	8,06	N	0,46	N	0,95	NA	NA	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14263	14263	C	G	MI.23336	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	411	137	E	D	gaG/gaC	4,29	0,87	0	benign	0,37	neutral	0,19	neutral	2,22	deleterious	-3,1	neutral	-2,03	medium_impact	2,49	neutral	0,83	neutral	0,53	deleterious	2,29	18,13	0,37	0,5	neutral	0,28	neutral	0,41	neutral	0,41	neutral	0,45	1	neutral	0,78	neutral	0,41	neutral	-3	deleterious	0,45	medium_impact	-0,58	medium_impact	-0,14	medium_impact	0,95	0,9	0,95	49,56	8,85	P	0,51	P	0,68	NA	NA	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14263	14263	C	A	MI.23337	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	411	137	E	D	gaG/gaT	4,29	0,87	0	benign	0,37	neutral	0,19	neutral	2,22	deleterious	-3,1	neutral	-2,03	medium_impact	2,49	neutral	0,83	neutral	0,53	deleterious	2,53	19,65	0,37	0,5	neutral	0,28	neutral	0,41	neutral	0,41	neutral	0,45	1	neutral	0,78	neutral	0,41	neutral	-3	deleterious	0,45	medium_impact	-0,58	medium_impact	-0,14	medium_impact	0,95	0,9	0,95	49,56	8,85	N	0,5	N	0,68	NA	NA	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14264	14264	T	A	MI.23338	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	410	137	E	V	gAg/gTg	-3,96	0	0	possibly_damaging	0,7	neutral	0,47	neutral	2,24	deleterious	-4,86	deleterious	-5,05	medium_impact	2,04	neutral	0,79	neutral	0,68	deleterious	4,27	24	0,28	0,45	neutral	0,4	disease	0,53	neutral	0,35	neutral	0,47	1	neutral	0,69	neutral	0,39	NA	0	deleterious	0,64	low_impact	-1,13	medium_impact	0,18	medium_impact	0,57	0,81	0,85	49,56	8,85	N	0,39	N	0,82	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14264	14264	T	C	MI.23339	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	410	137	E	G	gAg/gGg	-3,96	0	0	benign	0,02	neutral	0,35	neutral	2,3	deleterious	-4,34	deleterious	-3,75	neutral_impact	0,3	neutral	0,92	neutral	0,91	neutral	1,1	11,22	0,4	0,5	neutral	0,2	neutral	0,11	neutral	0,4	neutral	0,27	5	neutral	0,64	deleterious	0,67	neutral	-6	neutral	0,12	medium_impact	0,75	medium_impact	0,06	medium_impact	-0,89	0,7	0,85	49,56	8,85	N	0,53	P	0,31	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6116	6116	A	T	MI.2334	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	213	71	M	I	atA/atT	7,53	1	0,01	probably_damaging	0,98	deleterious	0	neutral	2,8	neutral	-0,6	deleterious	-2,52	high_impact	3,78	damaging	0,53	damaging	0,1	deleterious	3,41	23	0,42	0,55	neutral	0,24	disease	0,91	disease	0,61	disease	0,54	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,35	low_impact	-1,48	high_impact	2,39	0,61	0,9	1,95	6,89	P	0,52	P	0,87	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14264	14264	T	G	MI.23340	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	410	137	E	A	gAg/gCg	-3,96	0	0	benign	0,37	neutral	0,47	neutral	2,27	deleterious	-3,9	deleterious	-3,77	medium_impact	2,15	neutral	0,75	neutral	0,76	deleterious	2,33	18,38	0,35	0,5	neutral	0,21	neutral	0,37	neutral	0,49	neutral	0,45	1	neutral	0,46	deleterious	0,55	neutral	-3	neutral	0,39	medium_impact	-0,58	medium_impact	0,18	medium_impact	0,66	0,84	0,9	49,56	8,85	N	0,39	N	0,59	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14265	14265	C	G	MI.23341	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	409	137	E	Q	Gag/Cag	0,63	0,02	0	possibly_damaging	0,76	neutral	0,26	neutral	2,24	deleterious	-4,06	neutral	-2,02	low_impact	1,68	neutral	0,89	neutral	0,77	deleterious	2,38	18,67	0,48	0,55	neutral	0,3	neutral	0,23	neutral	0,28	neutral	0,42	2	neutral	0,83	neutral	0,25	neutral	-3	deleterious	0,58	low_impact	-1,26	medium_impact	-0,05	medium_impact	0,27	0,89	0,9	49,56	8,85	N	0,51	P	0,48	NA	NA	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14265	14265	C	T	MI.23342	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	409	137	E	K	Gag/Aag	0,63	0,02	0	possibly_damaging	0,49	neutral	0,27	neutral	2,27	deleterious	-3,58	neutral	-2,43	medium_impact	2,08	neutral	0,87	neutral	0,53	deleterious	2,13	17,08	0,4	0,5	neutral	0,24	disease	0,56	neutral	0,5	neutral	0,46	1	neutral	0,7	neutral	0,39	NA	0	deleterious	0,54	medium_impact	-0,78	medium_impact	-0,03	medium_impact	0,6	0,89	0,9	49,56	8,85	N	0,43	N	0,78	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14267	14267	C	A	MI.23343	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	407	136	R	L	cGg/cTg	-1,21	0	0	probably_damaging	0,92	neutral	0,73	neutral	2,13	deleterious	-4,56	deleterious	-3,19	medium_impact	2,16	neutral	0,84	neutral	0,72	deleterious	2,7	20,8	0,41	0,5	neutral	0,25	disease	0,91	disease	0,58	disease	0,59	2	neutral	0,9	neutral	0,41	deleterious	1	deleterious	0,76	low_impact	-1,77	medium_impact	0,45	medium_impact	0,67	0,51	0,8	18,14	17,08	N	0,23	N	0,57	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14267	14267	C	G	MI.23344	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	407	136	R	P	cGg/cCg	-1,21	0	0	probably_damaging	0,98	neutral	0,19	neutral	2,08	deleterious	-5,6	deleterious	-2,85	medium_impact	3,17	neutral	0,64	damaging	0,16	deleterious	3,23	22,8	0,23	0,45	disease	0,57	disease	0,94	disease	0,66	disease	0,82	6	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,84	low_impact	-2,35	medium_impact	-0,14	medium_impact	1,52	0,62	0,8	18,14	17,08	N	0,3	N	0,83	NA	NA	0,61	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14267	14267	C	T	MI.23345	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	407	136	R	Q	cGg/cAg	-1,21	0	0	probably_damaging	0,92	neutral	0,27	neutral	2,16	deleterious	-4,15	neutral	-1,08	medium_impact	3,17	neutral	0,76	damaging	0,27	deleterious	3,4	23	0,42	0,5	neutral	0,34	disease	0,79	neutral	0,49	disease	0,65	3	neutral	0,93	neutral	0,18	deleterious	1	deleterious	0,72	low_impact	-1,77	medium_impact	-0,03	medium_impact	1,52	0,8	0,85	18,14	17,08	N	0,32	N	0,59	NA	NA	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14268	14268	G	C	MI.23346	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	406	136	R	G	Cgg/Ggg	0,86	0	0	probably_damaging	0,92	neutral	0,37	neutral	2,11	deleterious	-4,86	neutral	-2,05	low_impact	1,66	neutral	0,88	neutral	0,88	deleterious	1,9	15,61	0,35	0,5	neutral	0,48	disease	0,68	disease	0,55	disease	0,5	0	neutral	0,92	neutral	0,23	neutral	-2	deleterious	0,72	low_impact	-1,77	medium_impact	0,08	medium_impact	0,25	0,67	0,85	18,14	17,08	N	0,32	N	0,43	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14268	14268	G	A	MI.23347	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	406	136	R	W	Cgg/Tgg	0,86	0	0	probably_damaging	0,99	neutral	0,18	neutral	2,06	deleterious	-7,47	deleterious	-4,16	high_impact	3,52	damaging	0,59	damaging	0,11	deleterious	3,68	23,3	0,3	0,45	disease	0,82	disease	0,9	disease	0,52	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-2,63	medium_impact	-0,16	medium_impact	1,81	0,69	0,85	18,14	17,08	N	0,32	N	0,85	NA	NA	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14269	14269	A	C	MI.23348	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	405	135	I	M	atT/atG	0,17	0	0	possibly_damaging	0,81	neutral	0,39	neutral	2,23	deleterious	-4,19	neutral	-0,63	low_impact	1,38	neutral	0,88	neutral	0,92	neutral	1,39	12,72	0,44	0,55	neutral	0,15	neutral	0,33	neutral	0,28	neutral	0,45	1	neutral	0,82	neutral	0,29	neutral	-3	deleterious	0,54	low_impact	-1,37	medium_impact	0,1	medium_impact	0,02	0,9	0,95	17,7	17,51	N	0,41	N	0,34	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14269	14269	A	T	MI.23349	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	405	135	I	M	atT/atA	0,17	0	0	possibly_damaging	0,81	neutral	0,39	neutral	2,23	deleterious	-4,19	neutral	-0,63	low_impact	1,38	neutral	0,88	neutral	0,92	neutral	1,56	13,61	0,44	0,55	neutral	0,15	neutral	0,33	neutral	0,28	neutral	0,45	1	neutral	0,82	neutral	0,29	neutral	-3	deleterious	0,54	low_impact	-1,37	medium_impact	0,1	medium_impact	0,02	0,9	0,95	17,7	17,51	N	0,4	N	0,34	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6116	6116	A	C	MI.2335	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	213	71	M	I	atA/atC	7,53	1	0,01	probably_damaging	0,98	deleterious	0	neutral	2,8	neutral	-0,6	deleterious	-2,52	high_impact	3,78	damaging	0,53	damaging	0,1	deleterious	3,34	22,9	0,42	0,55	neutral	0,24	disease	0,91	disease	0,61	disease	0,54	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,35	low_impact	-1,48	high_impact	2,39	0,61	0,9	1,95	6,89	P	0,5	N	0,87	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14270	14270	A	C	MI.23350	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	404	135	I	S	aTt/aGt	-2,12	0	0	possibly_damaging	0,66	neutral	0,45	neutral	2,24	deleterious	-4,68	deleterious	-3,46	low_impact	1,74	neutral	0,82	neutral	0,78	deleterious	3,98	23,6	0,34	0,5	neutral	0,38	disease	0,64	neutral	0,41	neutral	0,48	0	neutral	0,66	neutral	0,4	neutral	-3	deleterious	0,51	low_impact	-1,06	medium_impact	0,16	medium_impact	0,32	0,62	0,8	17,7	17,51	N	0,3	N	0,74	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14270	14270	A	T	MI.23351	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	404	135	I	N	aTt/aAt	-2,12	0	0	possibly_damaging	0,9	neutral	0,25	neutral	2,19	deleterious	-5,64	deleterious	-4,46	medium_impact	2,48	neutral	0,78	neutral	0,38	deleterious	4,21	23,9	0,31	0,45	disease	0,55	disease	0,75	disease	0,64	disease	0,76	5	neutral	0,93	neutral	0,18	NA	0	deleterious	0,76	low_impact	-1,67	medium_impact	-0,06	medium_impact	0,94	0,62	0,8	17,7	17,51	N	0,3	N	0,8	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14270	14270	A	G	MI.23352	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	404	135	I	T	aTt/aCt	-2,12	0	0	benign	0,37	neutral	0,28	neutral	2,24	deleterious	-4,26	deleterious	-2,8	medium_impact	2,48	neutral	0,84	neutral	0,56	deleterious	3,29	22,8	0,37	0,5	neutral	0,32	neutral	0,47	disease	0,51	disease	0,52	0	neutral	0,67	neutral	0,46	neutral	-3	neutral	0,41	medium_impact	-0,58	medium_impact	-0,02	medium_impact	0,94	0,68	0,85	17,7	17,51	N	0,44	N	0,59	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14271	14271	T	A	MI.23353	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	403	135	I	F	Att/Ttt	7,04	0,66	0	benign	0,03	neutral	0,73	neutral	2,27	deleterious	-4,31	neutral	1,05	neutral_impact	0,53	neutral	0,9	neutral	0,95	neutral	1,65	14,14	0,41	0,5	neutral	0,12	neutral	0,35	neutral	0,28	neutral	0,44	1	neutral	0,22	deleterious	0,85	neutral	-6	neutral	0,12	medium_impact	0,59	medium_impact	0,45	medium_impact	-0,7	0,84	0,9	17,7	17,51	N	0,44	N	0,18	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14271	14271	T	C	MI.23354	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	403	135	I	V	Att/Gtt	7,04	0,66	0	benign	0,01	neutral	0,53	neutral	2,46	neutral	-1,8	neutral	-0,56	neutral_impact	0,08	neutral	0,96	neutral	0,99	neutral	-1,58	0	0,48	0,55	neutral	0,17	neutral	0,08	neutral	0,25	neutral	0,23	5	neutral	0,46	deleterious	0,76	neutral	-6	neutral	0,09	medium_impact	1,03	medium_impact	0,24	low_impact	-1,07	0,73	0,85	17,7	17,51	P	0,55	P	0,54	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14271	14271	T	G	MI.23355	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	403	135	I	L	Att/Ctt	7,04	0,66	0	benign	0,12	neutral	1	neutral	2,39	neutral	-2,08	neutral	-0,43	low_impact	1,01	neutral	0,89	neutral	0,96	deleterious	0,51	7,53	0,35	0,5	neutral	0,14	neutral	0,28	neutral	0,24	neutral	0,42	2	neutral	0,12	deleterious	0,94	neutral	-6	neutral	0,17	medium_impact	0	high_impact	1,87	medium_impact	-0,29	0,75	0,85	17,7	17,51	N	0,48	N	0,29	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14272	14272	C	G	MI.23356	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	402	134	L	F	ttG/ttC	-1,89	0	0	probably_damaging	0,92	neutral	0,73	neutral	2,21	deleterious	-4,41	neutral	0,23	low_impact	1,31	neutral	0,91	neutral	0,96	neutral	1,27	12,11	0,44	0,55	neutral	0,14	neutral	0,28	neutral	0,42	neutral	0,43	1	neutral	0,91	neutral	0,41	neutral	-2	deleterious	0,63	low_impact	-1,77	medium_impact	0,45	medium_impact	-0,04	0,77	0,85	49,56	8,76	N	0,3	N	0,19	NA	NA	0,18	rs2853814	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14272	14272	C	A	MI.23357	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	402	134	L	F	ttG/ttT	-1,89	0	0	probably_damaging	0,92	neutral	0,73	neutral	2,21	deleterious	-4,41	neutral	0,23	low_impact	1,31	neutral	0,91	neutral	0,96	neutral	1,73	14,57	0,44	0,55	neutral	0,14	neutral	0,28	neutral	0,42	neutral	0,43	1	neutral	0,91	neutral	0,41	neutral	-2	deleterious	0,63	low_impact	-1,77	medium_impact	0,45	medium_impact	-0,04	0,77	0,85	49,56	8,76	N	0,38	N	0,19	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14273	14273	A	C	MI.23358	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	401	134	L	W	tTg/tGg	-7,4	0	0	probably_damaging	0,99	neutral	0,19	neutral	2,13	deleterious	-7,24	neutral	-2,23	medium_impact	3,08	neutral	0,78	neutral	0,49	neutral	1,7	14,43	0,25	0,45	disease	0,72	disease	0,69	disease	0,68	disease	0,73	5	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,77	low_impact	-2,63	medium_impact	-0,14	medium_impact	1,44	0,69	0,85	49,56	8,76	N	0,36	N	0,54	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14273	14273	A	G	MI.23359	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	401	134	L	S	tTg/tCg	-7,4	0	0	probably_damaging	0,98	neutral	0,44	neutral	2,21	deleterious	-5,22	deleterious	-2,83	low_impact	1,94	neutral	0,81	neutral	0,83	deleterious	2,87	21,7	0,35	0,5	neutral	0,43	neutral	0,5	neutral	0,5	neutral	0,48	0	deleterious	0,98	neutral	0,23	neutral	-2	deleterious	0,73	low_impact	-2,35	medium_impact	0,15	medium_impact	0,49	0,79	0,85	49,56	8,76	N	0,33	N	0,63	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6117	6117	C	G	MI.2336	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	214	72	P	A	Ccc/Gcc	-1,72	0	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-1,34	deleterious	-5,18	high_impact	4,63	neutral	0,68	damaging	0,12	deleterious	2,99	22,2	0,25	0,55	disease	0,53	disease	0,79	disease	0,68	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	3,18	0,62	0,9	3,12	6,81	N	0,45	N	0,76	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14274	14274	A	T	MI.23360	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	400	134	L	M	Ttg/Atg	1,31	0	0	probably_damaging	0,99	neutral	0,25	neutral	2,2	deleterious	-4,39	neutral	-0,37	low_impact	1,52	neutral	0,89	neutral	0,91	deleterious	2,71	20,9	0,32	0,5	neutral	0,33	neutral	0,22	neutral	0,39	neutral	0,42	2	deleterious	0,99	neutral	0,13	neutral	-2	deleterious	0,67	low_impact	-2,63	medium_impact	-0,06	medium_impact	0,13	0,82	0,85	49,56	8,76	P	0,58	P	0,42	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14274	14274	A	C	MI.23361	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	400	134	L	V	Ttg/Gtg	1,31	0	0	probably_damaging	0,93	neutral	0,53	neutral	2,37	deleterious	-3,31	neutral	-0,37	low_impact	0,9	neutral	0,89	neutral	0,99	neutral	1,49	13,28	0,42	0,5	neutral	0,09	neutral	0,12	neutral	0,36	neutral	0,24	5	neutral	0,92	neutral	0,3	neutral	-2	deleterious	0,6	low_impact	-1,83	medium_impact	0,24	medium_impact	-0,39	0,8	0,85	49,56	8,76	N	0,42	N	0,19	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14276	14276	C	T	MI.23362	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	398	133	G	E	gGg/gAg	-7,17	0	0	possibly_damaging	0,51	neutral	0,43	neutral	2,27	deleterious	-5,32	deleterious	-4,66	low_impact	1,89	neutral	0,9	neutral	0,81	neutral	1,31	12,34	0,35	0,5	neutral	0,31	disease	0,8	neutral	0,44	disease	0,59	2	neutral	0,56	neutral	0,46	neutral	-3	deleterious	0,63	medium_impact	-0,81	medium_impact	0,14	medium_impact	0,44	0,7	0,85	50	8,72	N	0,38	N	0,96	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14276	14276	C	A	MI.23363	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	398	133	G	V	gGg/gTg	-7,17	0	0	probably_damaging	0,98	neutral	0,76	neutral	2,28	deleterious	-5,73	deleterious	-5,85	medium_impact	2,02	neutral	0,83	neutral	0,67	deleterious	4,45	24,2	0,29	0,45	neutral	0,34	disease	0,8	neutral	0,46	disease	0,59	2	deleterious	0,98	neutral	0,39	deleterious	1	deleterious	0,77	low_impact	-2,35	medium_impact	0,48	medium_impact	0,55	0,74	0,85	50	8,72	N	0,26	N	0,98	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14276	14276	C	G	MI.23364	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	398	133	G	A	gGg/gCg	-7,17	0	0	possibly_damaging	0,9	neutral	0,6	neutral	2,29	deleterious	-4,4	deleterious	-3,93	medium_impact	2,72	neutral	0,86	neutral	0,69	deleterious	3,39	23	0,42	0,55	neutral	0,16	disease	0,67	neutral	0,4	neutral	0,46	1	neutral	0,89	neutral	0,35	NA	0	deleterious	0,69	low_impact	-1,67	medium_impact	0,3	medium_impact	1,14	0,8	0,85	50	8,72	N	0,28	N	0,69	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14277	14277	C	G	MI.23365	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	397	133	G	R	Ggg/Cgg	0,63	0	0	probably_damaging	0,97	neutral	0,39	neutral	2,24	deleterious	-5,95	deleterious	-5,43	medium_impact	3,06	neutral	0,81	neutral	0,34	deleterious	4,26	23,9	0,31	0,45	neutral	0,39	disease	0,85	disease	0,57	disease	0,78	6	neutral	0,97	neutral	0,21	deleterious	1	deleterious	0,8	low_impact	-2,18	medium_impact	0,1	medium_impact	1,42	0,96	1	50	8,72	N	0,3	N	0,96	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14277	14277	C	A	MI.23366	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	397	133	G	W	Ggg/Tgg	0,63	0	0	probably_damaging	1	neutral	0,16	neutral	2,19	deleterious	-8,54	deleterious	-5,9	medium_impact	2,86	neutral	0,87	neutral	0,61	deleterious	4,91	25	0,22	0,45	disease	0,8	disease	0,89	neutral	0,46	disease	0,78	6	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,85	low_impact	-3,55	medium_impact	-0,19	medium_impact	1,26	0,61	0,8	50	8,72	N	0,41	N	0,98	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14279	14279	G	C	MI.23367	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	395	132	S	W	tCa/tGa	-8,08	0	0,01	probably_damaging	0,91	neutral	0,18	neutral	2,21	deleterious	-7,43	neutral	-2,33	medium_impact	1,99	neutral	0,77	neutral	0,79	deleterious	2,86	21,7	0,27	0,45	disease	0,79	disease	0,78	neutral	0,4	disease	0,68	4	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,75	low_impact	-1,72	medium_impact	-0,16	medium_impact	0,53	0,58	0,8	48,23	8,73	N	0,32	N	0,73	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14279	14279	G	A	MI.23368	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	395	132	S	L	tCa/tTa	-8,08	0	0,01	benign	0,01	neutral	0,65	neutral	2,39	deleterious	-4,34	neutral	-0,2	neutral_impact	0,76	neutral	0,91	neutral	0,96	deleterious	0,38	6,47	0,28	0,45	neutral	0,34	neutral	0,48	neutral	0,36	neutral	0,45	1	neutral	0,33	deleterious	0,82	neutral	-6	neutral	0,16	medium_impact	1,03	medium_impact	0,36	medium_impact	-0,5	0,82	0,85	48,23	8,73	N	0,42	N	0,58	NA	NA	0,18	rs869025187	Pathogenic	Leber's_optic_atrophy	RCV000055705.1	MedGen:OMIM:SNOMED_CT	endometrial tumor	.	CPD	1,34	G14279A	LHON	+	-	Reported	2
chrM	14280	14280	A	G	MI.23369	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	394	132	S	P	Tca/Cca	-0,06	0	0,01	benign	0,01	neutral	0,2	neutral	2,23	deleterious	-4,83	neutral	-1,86	low_impact	1,19	neutral	0,87	neutral	0,8	neutral	0,96	10,46	0,21	0,45	neutral	0,43	disease	0,81	neutral	0,38	disease	0,63	3	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,23	medium_impact	1,03	medium_impact	-0,13	medium_impact	-0,14	0,65	0,8	48,23	8,73	N	0,42	N	0,01	NA	NA	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6117	6117	C	A	MI.2337	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	214	72	P	T	Ccc/Acc	-1,72	0	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-1,87	deleterious	-5,18	high_impact	4,29	neutral	0,63	damaging	0,08	deleterious	3,57	23,1	0,29	0,55	disease	0,51	disease	0,87	disease	0,7	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,86	0,64	0,9	3,12	6,81	N	0,35	N	0,8	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14280	14280	A	C	MI.23370	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	394	132	S	A	Tca/Gca	-0,06	0	0,01	benign	0,01	neutral	0,5	neutral	2,3	neutral	-2,7	neutral	-0,33	low_impact	1,79	neutral	0,87	neutral	0,82	neutral	-0,32	0,6	0,35	0,5	neutral	0,23	neutral	0,44	neutral	0,32	neutral	0,46	1	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	0,21	medium_impact	0,36	0,71	0,85	48,23	8,73	N	0,35	N	0,3	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14280	14280	A	T	MI.23371	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	394	132	S	T	Tca/Aca	-0,06	0	0,01	benign	0,02	neutral	0,39	neutral	2,28	deleterious	-3,46	neutral	-0,22	low_impact	1,37	neutral	0,91	neutral	0,9	deleterious	0,2	4,73	0,25	0,45	neutral	0,28	neutral	0,35	neutral	0,36	neutral	0,44	1	neutral	0,59	deleterious	0,69	neutral	-6	neutral	0,12	medium_impact	0,75	medium_impact	0,1	medium_impact	0,01	0,71	0,85	48,23	8,73	N	0,45	N	0,33	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14282	14282	C	T	MI.23372	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	392	131	G	E	gGg/gAg	-4,87	0	0	possibly_damaging	0,61	neutral	0,3	neutral	2,34	deleterious	-5,32	neutral	-0,6	low_impact	1,05	neutral	0,87	neutral	0,86	deleterious	0,56	7,88	0,37	0,5	neutral	0,21	disease	0,72	neutral	0,34	disease	0,55	1	neutral	0,72	neutral	0,35	neutral	-3	deleterious	0,6	medium_impact	-0,97	medium_impact	0	medium_impact	-0,26	0,68	0,85	44,69	8,63	N	0,36	N	0,64	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14282	14282	C	G	MI.23373	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	392	131	G	A	gGg/gCg	-4,87	0	0	probably_damaging	0,93	neutral	0,53	neutral	2,36	deleterious	-4,4	neutral	-2,19	medium_impact	3,06	neutral	0,62	neutral	0,61	deleterious	2,14	17,13	0,37	0,5	neutral	0,32	disease	0,74	neutral	0,39	disease	0,57	1	neutral	0,92	neutral	0,3	deleterious	1	deleterious	0,73	low_impact	-1,83	medium_impact	0,24	medium_impact	1,42	0,73	0,85	44,69	8,63	N	0,32	N	0,59	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14282	14282	C	A	MI.23374	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	392	131	G	V	gGg/gTg	-4,87	0	0	probably_damaging	0,99	neutral	0,53	neutral	2,3	deleterious	-5,73	deleterious	-3,77	medium_impact	2,51	neutral	0,74	neutral	0,65	deleterious	3,33	22,9	0,28	0,45	disease	0,55	disease	0,85	neutral	0,4	disease	0,6	2	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,81	low_impact	-2,63	medium_impact	0,24	medium_impact	0,96	0,73	0,85	44,69	8,63	N	0,26	N	0,85	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14283	14283	C	G	MI.23375	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	391	131	G	R	Ggg/Cgg	-0,06	0	0	probably_damaging	0,98	neutral	0,36	neutral	2,3	deleterious	-5,95	deleterious	-2,75	medium_impact	3,06	damaging	0,58	neutral	0,36	deleterious	3,1	22,5	0,27	0,45	neutral	0,48	disease	0,87	disease	0,55	disease	0,76	5	deleterious	0,98	neutral	0,19	deleterious	1	deleterious	0,81	low_impact	-2,35	medium_impact	0,07	medium_impact	1,42	0,89	0,9	44,69	8,63	N	0,37	N	0,81	NA	NA	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14283	14283	C	A	MI.23376	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	391	131	G	W	Ggg/Tgg	-0,06	0	0	probably_damaging	1	neutral	0,18	neutral	2,29	deleterious	-8,54	deleterious	-4,13	medium_impact	2,86	neutral	0,68	neutral	0,66	deleterious	5,01	25,1	0,23	0,45	disease	0,88	disease	0,9	disease	0,6	disease	0,78	6	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,85	low_impact	-3,55	medium_impact	-0,16	medium_impact	1,26	0,61	0,8	44,69	8,63	N	0,33	N	0,88	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14284	14284	C	G	MI.23377	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	390	130	E	D	gaG/gaC	1,77	0	0	benign	0,36	neutral	0,35	neutral	2,27	deleterious	-3,1	neutral	-0,28	low_impact	1,58	neutral	0,89	neutral	0,9	deleterious	-0,02	2,38	0,31	0,45	neutral	0,12	neutral	0,27	neutral	0,27	neutral	0,43	1	neutral	0,58	deleterious	0,5	neutral	-6	neutral	0,3	medium_impact	-0,57	medium_impact	0,06	medium_impact	0,18	0,84	0,9	49,12	8,75	N	0,52	P	0,26	NA	NA	0,17	rs28357673	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14285	14285	T	A	MI.23378	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	389	130	E	V	gAg/gTg	-5,79	0	0	probably_damaging	0,99	neutral	0,57	neutral	2,21	deleterious	-4,86	deleterious	-4,32	low_impact	1,68	neutral	0,86	neutral	0,73	deleterious	3,33	22,9	0,23	0,45	neutral	0,47	disease	0,55	neutral	0,4	neutral	0,47	1	deleterious	0,99	neutral	0,29	neutral	-2	deleterious	0,75	low_impact	-2,63	medium_impact	0,27	medium_impact	0,27	0,73	0,85	49,12	8,75	N	0,25	N	0,77	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14285	14285	T	G	MI.23379	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	389	130	E	A	gAg/gCg	-5,79	0	0	probably_damaging	0,96	neutral	0,68	neutral	2,26	deleterious	-3,9	deleterious	-2,6	medium_impact	2,32	neutral	0,8	neutral	0,44	deleterious	2,37	18,63	0,28	0,45	neutral	0,25	neutral	0,49	neutral	0,43	neutral	0,46	1	neutral	0,95	neutral	0,36	deleterious	1	deleterious	0,69	low_impact	-2,06	medium_impact	0,39	medium_impact	0,8	0,7	0,85	49,12	8,75	N	0,21	N	0,59	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6117	6117	C	T	MI.2338	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	214	72	P	S	Ccc/Tcc	-1,72	0	0	probably_damaging	1	deleterious	0	neutral	2,75	neutral	-2,32	deleterious	-5,18	high_impact	4,63	damaging	0,57	damaging	0,11	deleterious	3,78	23,4	0,35	0,55	disease	0,66	disease	0,84	disease	0,68	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,18	0,28	0,9	3,12	6,81	N	0,44	N	0,85	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14285	14285	T	C	MI.23380	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	389	130	E	G	gAg/gGg	-5,79	0	0	probably_damaging	0,98	neutral	0,42	neutral	2,31	deleterious	-4,34	neutral	-0,67	low_impact	0,88	neutral	0,88	neutral	0,95	deleterious	2,19	17,45	0,26	0,45	neutral	0,11	neutral	0,2	neutral	0,42	neutral	0,37	3	neutral	0,97	neutral	0,22	neutral	-2	deleterious	0,63	low_impact	-2,35	medium_impact	0,13	medium_impact	-0,4	0,63	0,8	49,12	8,75	N	0,37	N	0,23	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14286	14286	C	G	MI.23381	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	388	130	E	Q	Gag/Cag	-0,98	0	0	probably_damaging	0,98	neutral	0,43	neutral	2,25	deleterious	-4,06	neutral	-1,56	medium_impact	2,43	neutral	0,8	neutral	0,35	deleterious	2,13	17,04	0,37	0,5	neutral	0,27	neutral	0,27	neutral	0,38	neutral	0,44	1	deleterious	0,98	neutral	0,23	deleterious	1	deleterious	0,67	low_impact	-2,35	medium_impact	0,14	medium_impact	0,9	0,8	0,85	49,12	8,75	N	0,38	N	0,73	NA	NA	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14286	14286	C	T	MI.23382	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	388	130	E	K	Gag/Aag	-0,98	0	0	probably_damaging	0,96	neutral	0,5	neutral	2,29	deleterious	-3,58	neutral	-1,87	low_impact	1,58	neutral	0,77	neutral	0,29	deleterious	2,83	21,5	0,31	0,45	neutral	0,24	neutral	0,43	neutral	0,43	neutral	0,45	1	neutral	0,95	neutral	0,27	neutral	-2	deleterious	0,7	low_impact	-2,06	medium_impact	0,21	medium_impact	0,18	0,86	0,9	49,12	8,75	N	0,27	N	0,76	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14288	14288	C	G	MI.23383	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	386	129	G	A	gGa/gCa	-12,67	0	0	probably_damaging	0,96	neutral	0,51	neutral	2,32	deleterious	-4,4	neutral	-0,87	low_impact	1,8	neutral	0,86	neutral	0,77	neutral	1,03	10,82	0,4	0,5	neutral	0,14	neutral	0,48	neutral	0,33	neutral	0,43	1	neutral	0,96	neutral	0,28	neutral	-2	deleterious	0,67	low_impact	-2,06	medium_impact	0,22	medium_impact	0,37	0,78	0,85	49,12	8,65	N	0,33	N	0,4	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14288	14288	C	T	MI.23384	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	386	129	G	E	gGa/gAa	-12,67	0	0	probably_damaging	0,99	neutral	0,3	neutral	2,3	deleterious	-5,32	neutral	-1,93	low_impact	1,88	neutral	0,87	neutral	0,74	deleterious	0	2,55	0,24	0,45	neutral	0,21	disease	0,62	neutral	0,34	neutral	0,44	1	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,72	low_impact	-2,63	medium_impact	0	medium_impact	0,44	0,76	0,85	49,12	8,65	N	0,39	N	0,69	NA	NA	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14288	14288	C	A	MI.23385	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	386	129	G	V	gGa/gTa	-12,67	0	0	probably_damaging	0,99	neutral	0,51	neutral	2,39	deleterious	-5,73	neutral	-1,56	low_impact	1,17	neutral	0,82	neutral	0,91	deleterious	2,48	19,32	0,26	0,45	neutral	0,15	disease	0,59	neutral	0,32	neutral	0,43	1	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,68	low_impact	-2,63	medium_impact	0,22	medium_impact	-0,16	0,7	0,85	49,12	8,65	N	0,29	N	0,34	NA	NA	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14289	14289	C	G	MI.23386	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	385	129	G	R	Gga/Cga	-2,81	0	0	probably_damaging	1	neutral	0,35	neutral	2,29	deleterious	-5,95	deleterious	-2,69	medium_impact	2,73	neutral	0,73	damaging	0,19	deleterious	2,32	18,32	0,27	0,45	neutral	0,26	disease	0,68	disease	0,52	disease	0,63	3	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,72	low_impact	-3,55	medium_impact	0,06	medium_impact	1,15	0,93	0,95	49,12	8,65	N	0,32	N	0,68	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14289	14289	C	A	MI.23387	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	385	129	G	W	Gga/Tga	-2,81	0	0	probably_damaging	1	neutral	0,19	neutral	2,26	deleterious	-8,54	deleterious	-3,42	medium_impact	2,38	neutral	0,8	damaging	0,26	deleterious	3,84	23,4	0,2	0,45	disease	0,65	disease	0,79	disease	0,54	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,79	low_impact	-3,55	medium_impact	-0,14	medium_impact	0,85	0,52	0,8	49,12	8,65	N	0,3	N	0,77	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14290	14290	T	A	MI.23388	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	384	128	E	D	gaA/gaT	-0,98	0	0	probably_damaging	1	neutral	0,22	neutral	2,3	deleterious	-3,1	neutral	1,24	low_impact	1,1	neutral	0,85	neutral	0,98	neutral	-0,42	0,35	0,38	0,5	neutral	0,09	neutral	0,22	neutral	0,24	neutral	0,38	2	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,64	low_impact	-3,55	medium_impact	-0,1	medium_impact	-0,22	0,83	0,9	19,91	15,56	N	0,45	N	0,08	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14290	14290	T	G	MI.23389	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	384	128	E	D	gaA/gaC	-0,98	0	0	probably_damaging	1	neutral	0,22	neutral	2,3	deleterious	-3,1	neutral	1,24	low_impact	1,1	neutral	0,85	neutral	0,98	neutral	-0,53	0,19	0,38	0,5	neutral	0,09	neutral	0,22	neutral	0,24	neutral	0,38	2	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,64	low_impact	-3,55	medium_impact	-0,1	medium_impact	-0,22	0,83	0,9	19,91	15,56	N	0,48	N	0,08	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6118	6118	C	T	MI.2339	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	215	72	P	L	cCc/cTc	4,52	1	0	probably_damaging	1	deleterious	0	neutral	2,74	neutral	-2,68	deleterious	-6,48	high_impact	4,38	neutral	0,61	damaging	0,08	deleterious	4,21	23,9	0,25	0,55	disease	0,76	disease	0,89	disease	0,66	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,95	0,65	0,9	3,12	6,81	P	0,5	N	0,87	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14291	14291	T	G	MI.23390	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	383	128	E	A	gAa/gCa	-1,89	0	0	probably_damaging	1	neutral	0,51	neutral	2,3	deleterious	-3,9	deleterious	-2,96	medium_impact	2,23	neutral	0,78	neutral	0,44	deleterious	4,05	23,7	0,29	0,45	neutral	0,3	disease	0,77	neutral	0,5	disease	0,66	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	0,22	medium_impact	0,73	0,77	0,85	19,91	15,56	N	0,24	N	0,7	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14291	14291	T	C	MI.23391	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	383	128	E	G	gAa/gGa	-1,89	0	0	probably_damaging	1	neutral	0,35	neutral	2,27	deleterious	-4,34	neutral	-1,98	low_impact	1,48	neutral	0,85	neutral	0,95	deleterious	2,72	20,9	0,34	0,5	neutral	0,35	disease	0,61	neutral	0,44	neutral	0,47	1	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,72	low_impact	-3,55	medium_impact	0,06	medium_impact	0,1	0,76	0,85	19,91	15,56	N	0,37	N	0,71	NA	NA	0,27	.	.	.	.	.	.	COSM1155551	.	.	.	.	.	.	.	.
chrM	14291	14291	T	A	MI.23392	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	383	128	E	V	gAa/gTa	-1,89	0	0	probably_damaging	1	neutral	0,51	neutral	2,27	deleterious	-4,86	deleterious	-4,25	medium_impact	2,08	neutral	0,76	neutral	0,33	deleterious	4,58	24,4	0,24	0,45	disease	0,51	disease	0,84	neutral	0,4	disease	0,72	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,79	low_impact	-3,55	medium_impact	0,22	medium_impact	0,6	0,82	0,85	19,91	15,56	N	0,32	N	0,83	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14292	14292	C	T	MI.23393	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	382	128	E	K	Gaa/Aaa	0,63	0,07	0	probably_damaging	1	neutral	0,3	neutral	2,31	deleterious	-3,58	neutral	-2,32	medium_impact	2,73	neutral	0,79	damaging	0,21	deleterious	4,72	24,6	0,42	0,55	neutral	0,27	disease	0,83	disease	0,52	disease	0,75	5	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,77	low_impact	-3,55	medium_impact	0	medium_impact	1,15	0,81	0,85	19,91	15,56	N	0,37	N	0,82	NA	NA	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14292	14292	C	G	MI.23394	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	382	128	E	Q	Gaa/Caa	0,63	0,07	0	probably_damaging	1	neutral	0,3	neutral	2,25	deleterious	-4,06	neutral	-1,62	medium_impact	3,27	neutral	0,76	neutral	0,36	deleterious	3,62	23,2	0,44	0,55	neutral	0,29	disease	0,6	neutral	0,47	disease	0,5	0	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,71	low_impact	-3,55	medium_impact	0	medium_impact	1,6	0,82	0,85	19,91	15,56	N	0,46	N	0,85	NA	NA	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14294	14294	T	C	MI.23395	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	380	127	Y	C	tAt/tGt	1,54	0,09	0	probably_damaging	0,96	neutral	0,18	neutral	2,26	deleterious	-6,77	deleterious	-6,53	low_impact	1,47	neutral	0,87	neutral	0,72	deleterious	2,25	17,85	0,38	0,5	disease	0,6	disease	0,78	neutral	0,38	disease	0,63	3	neutral	0,97	neutral	0,11	neutral	-2	deleterious	0,77	low_impact	-2,06	medium_impact	-0,16	medium_impact	0,09	0,25	0,8	50,44	8,73	N	0,45	N	0,95	NA	NA	0,54	.	.	.	.	.	.	COSM1138256	.	.	.	.	.	.	.	.
chrM	14294	14294	T	A	MI.23396	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	380	127	Y	F	tAt/tTt	1,54	0,09	0	benign	0,02	neutral	0,71	neutral	2,32	neutral	-2,93	neutral	-1,42	neutral_impact	-0,01	neutral	0,96	neutral	0,96	deleterious	0,16	4,26	0,52	0,6	neutral	0,29	neutral	0,29	neutral	0,26	neutral	0,44	1	neutral	0,26	deleterious	0,85	neutral	-6	neutral	0,17	medium_impact	0,75	medium_impact	0,42	low_impact	-1,15	0,52	0,8	50,44	8,73	N	0,4	N	0,41	NA	NA	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14294	14294	T	G	MI.23397	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	380	127	Y	S	tAt/tCt	1,54	0,09	0	possibly_damaging	0,76	neutral	0,45	neutral	2,39	deleterious	-4,84	deleterious	-6,76	low_impact	1,32	neutral	0,86	neutral	0,81	deleterious	3,72	23,3	0,33	0,5	neutral	0,29	disease	0,59	neutral	0,37	neutral	0,46	1	neutral	0,75	neutral	0,35	neutral	-3	deleterious	0,59	low_impact	-1,26	medium_impact	0,16	medium_impact	-0,03	0,52	0,8	50,44	8,73	N	0,38	N	0,93	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14295	14295	A	T	MI.23398	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	379	127	Y	N	Tat/Aat	-1,21	0	0	possibly_damaging	0,79	neutral	0,35	neutral	2,43	deleterious	-5,32	deleterious	-7,19	low_impact	1,55	neutral	0,78	neutral	0,65	deleterious	3,45	23	0,39	0,5	neutral	0,37	disease	0,7	neutral	0,46	disease	0,54	1	neutral	0,81	neutral	0,28	neutral	-3	deleterious	0,67	low_impact	-1,32	medium_impact	0,06	medium_impact	0,16	0,44	0,8	50,44	8,73	N	0,33	N	0,94	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14295	14295	A	G	MI.23399	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	379	127	Y	H	Tat/Cat	-1,21	0	0	benign	0,06	neutral	0,54	neutral	2,3	deleterious	-5,03	deleterious	-4,19	low_impact	1,9	neutral	0,84	neutral	0,61	deleterious	2,33	18,35	0,44	0,55	neutral	0,45	disease	0,59	neutral	0,45	neutral	0,5	0	neutral	0,4	deleterious	0,74	neutral	-6	neutral	0,24	medium_impact	0,3	medium_impact	0,25	medium_impact	0,45	0,56	0,8	50,44	8,73	N	0,3	N	0,87	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8636	8636	T	C	MI.234	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	110	37	L	P	cTc/cCc	0,59	0,38	0	probably_damaging	0,94	deleterious	0,03	neutral	4,3	deleterious	-3,46	deleterious	-4,25	medium_impact	3,21	neutral	0,92	neutral	0,58	deleterious	3,66	23,2	0,3	0,65	disease	0,88	disease	0,84	disease	0,7	disease	0,81	6	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,84	low_impact	-1,89	medium_impact	-0,56	medium_impact	1,65	0,48	0,9	20,35	20,89	N	0,37	N	0,61	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6118	6118	C	G	MI.2340	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	215	72	P	R	cCc/cGc	4,52	1	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-2,81	deleterious	-5,83	high_impact	5,18	damaging	0,6	damaging	0,07	deleterious	3,47	23	0,17	0,55	disease	0,87	disease	0,94	disease	0,8	disease	0,91	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,54	0,9	3,12	6,81	P	0,68	P	0,9	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14295	14295	A	C	MI.23400	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	379	127	Y	D	Tat/Gat	-1,21	0	0	possibly_damaging	0,84	neutral	0,25	neutral	2,36	deleterious	-5,53	deleterious	-7,82	low_impact	0,86	neutral	0,75	neutral	0,75	deleterious	3,42	23	0,31	0,45	neutral	0,41	disease	0,66	disease	0,51	neutral	0,48	0	neutral	0,88	neutral	0,21	neutral	-3	deleterious	0,71	low_impact	-1,46	medium_impact	-0,06	medium_impact	-0,42	0,52	0,8	50,44	8,73	N	0,36	N	0,93	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14296	14296	A	C	MI.23401	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	378	126	I	M	atT/atG	2,23	0	0	probably_damaging	0,94	neutral	0,3	neutral	2,2	deleterious	-4,19	neutral	-1,69	low_impact	1,59	neutral	0,88	neutral	0,96	deleterious	1,91	15,63	0,45	0,55	neutral	0,19	neutral	0,36	neutral	0,3	neutral	0,46	1	neutral	0,95	neutral	0,18	neutral	-2	deleterious	0,63	low_impact	-1,89	medium_impact	0	medium_impact	0,19	0,95	0,95	50,44	8,66	N	0,47	N	0,36	NA	NA	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14296	14296	A	T	MI.23402	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	378	126	I	M	atT/atA	2,23	0	0	probably_damaging	0,94	neutral	0,3	neutral	2,2	deleterious	-4,19	neutral	-1,69	low_impact	1,59	neutral	0,88	neutral	0,96	deleterious	2,02	16,33	0,45	0,55	neutral	0,19	neutral	0,36	neutral	0,3	neutral	0,46	1	neutral	0,95	neutral	0,18	neutral	-2	deleterious	0,63	low_impact	-1,89	medium_impact	0	medium_impact	0,19	0,95	0,95	50,44	8,66	N	0,46	N	0,36	NA	NA	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14297	14297	A	G	MI.23403	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	377	126	I	T	aTt/aCt	-0,75	0	0	possibly_damaging	0,79	neutral	0,4	neutral	2,19	deleterious	-4,26	deleterious	-2,96	low_impact	1,77	neutral	0,87	neutral	0,77	deleterious	3,16	22,6	0,44	0,55	neutral	0,18	disease	0,53	neutral	0,4	neutral	0,43	1	neutral	0,8	neutral	0,31	neutral	-3	deleterious	0,56	low_impact	-1,32	medium_impact	0,11	medium_impact	0,34	0,84	0,9	50,44	8,66	N	0,36	N	0,91	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14297	14297	A	C	MI.23404	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	377	126	I	S	aTt/aGt	-0,75	0	0	probably_damaging	0,92	neutral	0,5	neutral	2,16	deleterious	-4,68	deleterious	-4,09	low_impact	1,62	neutral	0,74	neutral	0,73	deleterious	3,81	23,4	0,35	0,5	neutral	0,27	disease	0,69	neutral	0,31	disease	0,53	1	neutral	0,91	neutral	0,29	neutral	-2	deleterious	0,68	low_impact	-1,77	medium_impact	0,21	medium_impact	0,22	0,75	0,85	50,44	8,66	N	0,34	N	0,86	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14297	14297	A	T	MI.23405	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	377	126	I	N	aTt/aAt	-0,75	0	0	probably_damaging	0,97	neutral	0,38	neutral	2,18	deleterious	-5,64	deleterious	-5	medium_impact	2,28	neutral	0,74	neutral	0,63	deleterious	3,88	23,5	0,32	0,5	neutral	0,24	disease	0,77	neutral	0,45	disease	0,61	2	neutral	0,97	neutral	0,21	deleterious	1	deleterious	0,71	low_impact	-2,18	medium_impact	0,09	medium_impact	0,77	0,72	0,85	50,44	8,66	N	0,41	N	0,97	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14298	14298	T	C	MI.23406	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	376	126	I	V	Att/Gtt	2,23	0	0	benign	0,03	neutral	0,7	neutral	2,33	neutral	-1,8	neutral	-0,1	neutral_impact	0,24	neutral	0,94	neutral	0,98	neutral	-1,08	0,01	0,5	0,6	neutral	0,15	neutral	0,11	neutral	0,26	neutral	0,22	6	neutral	0,24	deleterious	0,84	neutral	-6	neutral	0,1	medium_impact	0,59	medium_impact	0,41	medium_impact	-0,94	0,73	0,85	50,44	8,66	N	0,45	N	0,52	NA	NA	0,16	rs879200945	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14298	14298	T	G	MI.23407	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	376	126	I	L	Att/Ctt	2,23	0	0	possibly_damaging	0,45	neutral	0,85	neutral	2,44	neutral	-2,08	neutral	-1,36	low_impact	1,2	neutral	0,87	neutral	0,88	neutral	1,23	11,89	0,44	0,55	neutral	0,16	neutral	0,43	neutral	0,37	neutral	0,44	1	neutral	0,34	deleterious	0,7	neutral	-3	neutral	0,28	medium_impact	-0,72	medium_impact	0,63	medium_impact	-0,14	0,81	0,85	50,44	8,66	N	0,3	N	0,65	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14298	14298	T	A	MI.23408	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	376	126	I	F	Att/Ttt	2,23	0	0	probably_damaging	0,94	neutral	0,86	neutral	2,24	deleterious	-4,31	deleterious	-3,26	low_impact	1,56	neutral	0,76	neutral	0,77	deleterious	4,21	23,9	0,38	0,5	neutral	0,32	disease	0,68	neutral	0,3	neutral	0,5	0	neutral	0,93	neutral	0,46	neutral	-2	deleterious	0,66	low_impact	-1,89	medium_impact	0,64	medium_impact	0,17	0,83	0,85	50,44	8,66	N	0,25	N	0,84	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14299	14299	T	A	MI.23409	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	375	125	M	I	atA/atT	-3,27	0	0	benign	0,06	neutral	0,48	neutral	2,47	neutral	-2,28	neutral	0,72	low_impact	1,26	neutral	0,9	neutral	0,92	neutral	1,2	11,76	0,54	0,6	neutral	0,11	disease	0,52	neutral	0,36	neutral	0,43	1	neutral	0,47	deleterious	0,71	neutral	-6	neutral	0,16	medium_impact	0,3	medium_impact	0,19	medium_impact	-0,08	0,68	0,85	48,23	8,39	N	0,37	N	0,16	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6118	6118	C	A	MI.2341	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	215	72	P	H	cCc/cAc	4,52	1	0	probably_damaging	1	deleterious	0	neutral	2,65	deleterious	-3,88	deleterious	-5,83	high_impact	5,18	neutral	0,62	damaging	0,07	deleterious	4	23,6	0,2	0,55	disease	0,92	disease	0,89	disease	0,78	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,51	0,9	3,12	6,81	P	0,71	P	0,81	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14299	14299	T	G	MI.23410	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	375	125	M	I	atA/atC	-3,27	0	0	benign	0,06	neutral	0,48	neutral	2,47	neutral	-2,28	neutral	0,72	low_impact	1,26	neutral	0,9	neutral	0,92	deleterious	0,87	9,91	0,54	0,6	neutral	0,11	disease	0,52	neutral	0,36	neutral	0,43	1	neutral	0,47	deleterious	0,71	neutral	-6	neutral	0,16	medium_impact	0,3	medium_impact	0,19	medium_impact	-0,08	0,68	0,85	48,23	8,39	N	0,44	N	0,16	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14300	14300	A	G	MI.23411	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	374	125	M	T	aTa/aCa	-5,79	0	0	benign	0,14	neutral	0,44	neutral	2,35	deleterious	-3,69	neutral	-1,63	low_impact	1,26	neutral	0,85	neutral	0,85	neutral	1,38	12,69	0,44	0,55	neutral	0,27	disease	0,53	neutral	0,46	neutral	0,44	1	neutral	0,48	deleterious	0,65	neutral	-6	neutral	0,25	medium_impact	-0,07	medium_impact	0,15	medium_impact	-0,08	0,61	0,8	48,23	8,39	N	0,39	N	0,44	NA	NA	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14300	14300	A	T	MI.23412	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	374	125	M	K	aTa/aAa	-5,79	0	0	benign	0,34	neutral	0,33	neutral	2,36	deleterious	-3,95	deleterious	-3,04	medium_impact	2,5	neutral	0,77	neutral	0,7	deleterious	1,98	16,08	0,29	0,45	neutral	0,41	disease	0,75	neutral	0,47	disease	0,58	2	neutral	0,61	deleterious	0,5	neutral	-3	deleterious	0,48	medium_impact	-0,53	medium_impact	0,04	medium_impact	0,95	0,7	0,85	48,23	8,39	N	0,44	N	0,83	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14301	14301	T	G	MI.23413	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	373	125	M	L	Ata/Cta	0,17	0	0	benign	0,04	neutral	0,77	neutral	2,36	neutral	-1,28	neutral	-0,26	low_impact	0,9	neutral	0,9	neutral	0,95	deleterious	0,41	6,69	0,52	0,6	neutral	0,08	neutral	0,44	neutral	0,34	neutral	0,41	2	neutral	0,16	deleterious	0,87	neutral	-6	neutral	0,13	medium_impact	0,47	medium_impact	0,5	medium_impact	-0,39	0,7	0,85	48,23	8,39	N	0,36	N	0,27	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14301	14301	T	C	MI.23414	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	373	125	M	V	Ata/Gta	0,17	0	0	benign	0	neutral	0,62	neutral	2,33	neutral	-2,31	neutral	1,27	neutral_impact	-0,68	neutral	0,97	neutral	0,99	neutral	-2,11	0	0,65	0,7	neutral	0,08	neutral	0,22	neutral	0,32	neutral	0,38	2	neutral	0,37	deleterious	0,81	neutral	-6	neutral	0,1	medium_impact	1,95	medium_impact	0,32	low_impact	-1,71	0,76	0,85	48,23	8,39	N	0,4	N	0,08	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14301	14301	T	A	MI.23415	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	373	125	M	L	Ata/Tta	0,17	0	0	benign	0,04	neutral	0,77	neutral	2,36	neutral	-1,28	neutral	-0,26	low_impact	0,9	neutral	0,9	neutral	0,95	deleterious	0,52	7,55	0,52	0,6	neutral	0,08	neutral	0,44	neutral	0,34	neutral	0,41	2	neutral	0,16	deleterious	0,87	neutral	-6	neutral	0,13	medium_impact	0,47	medium_impact	0,5	medium_impact	-0,39	0,7	0,85	48,23	8,39	N	0,4	N	0,27	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14302	14302	T	A	MI.23416	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	372	124	W	C	tgA/tgT	-2,58	0	0	probably_damaging	1	neutral	0,18	neutral	2,3	deleterious	-7,1	deleterious	-12,53	medium_impact	3,19	neutral	0,75	neutral	0,36	deleterious	4,63	24,5	0,38	0,5	disease	0,83	disease	0,94	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,88	low_impact	-3,55	medium_impact	-0,16	medium_impact	1,53	0,51	0,8	19,91	7,92	N	0,45	N	0,96	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14302	14302	T	G	MI.23417	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	372	124	W	C	tgA/tgC	-2,58	0	0	probably_damaging	1	neutral	0,18	neutral	2,3	deleterious	-7,1	deleterious	-12,53	medium_impact	3,19	neutral	0,75	neutral	0,36	deleterious	4,36	24,1	0,38	0,5	disease	0,83	disease	0,94	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,88	low_impact	-3,55	medium_impact	-0,16	medium_impact	1,53	0,51	0,8	19,91	7,92	N	0,37	N	0,96	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14303	14303	C	A	MI.23418	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	371	124	W	L	tGa/tTa	-5,79	0	0	probably_damaging	1	neutral	0,72	neutral	2,45	deleterious	-4,25	deleterious	-12,33	medium_impact	2,18	neutral	0,86	neutral	0,67	deleterious	4,65	24,5	0,34	0,5	disease	0,58	disease	0,84	disease	0,62	disease	0,61	2	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,83	low_impact	-3,55	medium_impact	0,43	medium_impact	0,69	0,45	0,8	19,91	7,92	N	0,3	N	0,96	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14303	14303	C	G	MI.23419	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	371	124	W	S	tGa/tCa	-5,79	0	0	probably_damaging	1	neutral	0,47	neutral	2,39	deleterious	-5,45	deleterious	-13,37	low_impact	1,87	neutral	0,8	neutral	0,32	deleterious	4,26	23,9	0,34	0,5	disease	0,58	disease	0,93	disease	0,63	disease	0,62	2	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,86	low_impact	-3,55	medium_impact	0,18	medium_impact	0,43	0,55	0,8	19,91	7,92	N	0,33	N	0,95	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6120	6120	A	G	MI.2342	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	217	73	I	V	Atc/Gtc	-12,6	0	0	probably_damaging	0,95	neutral	0,5	neutral	2,81	neutral	0,05	neutral	-0,5	low_impact	1,1	neutral	0,68	neutral	0,74	neutral	1,54	13,54	0,57	0,6	neutral	0,29	neutral	0,31	neutral	0,27	neutral	0,45	1	neutral	0,95	neutral	0,28	neutral	-2	deleterious	0,61	low_impact	-1,96	medium_impact	0,19	medium_impact	-0,08	0,54	0,9	5,65	37,31	N	0,42	N	0,25	polymorphism	1	0,02	rs878853023	Uncertain significance	not_provided	RCV000224535.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	14304	14304	A	G	MI.23420	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	370	124	W	R	Tga/Cga	-0,29	0	0	probably_damaging	1	neutral	0,35	neutral	2,31	deleterious	-5,59	deleterious	-13,51	high_impact	3,54	neutral	0,76	damaging	0,12	deleterious	3,78	23,4	0,42	0,55	disease	0,67	disease	0,92	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,55	medium_impact	0,06	medium_impact	1,83	0,53	0,8	19,91	7,92	N	0,41	N	0,94	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14304	14304	A	C	MI.23421	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	370	124	W	G	Tga/Gga	-0,29	0	0	probably_damaging	1	neutral	0,36	neutral	2,51	deleterious	-5,63	deleterious	-12,48	medium_impact	2,09	neutral	0,8	neutral	0,46	deleterious	3,67	23,3	0,37	0,5	neutral	0,3	disease	0,88	disease	0,64	disease	0,61	2	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-3,55	medium_impact	0,07	medium_impact	0,61	0,63	0,8	19,91	7,92	N	0,34	N	0,91	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14306	14306	C	T	MI.23422	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	368	123	S	N	aGc/aAc	-0,29	0	0	benign	0,01	neutral	0,37	neutral	2,27	deleterious	-4,18	neutral	0,83	low_impact	1,63	neutral	0,89	neutral	0,88	deleterious	0,66	8,53	0,55	0,6	neutral	0,27	disease	0,51	neutral	0,39	neutral	0,48	0	neutral	0,62	deleterious	0,68	neutral	-6	neutral	0,17	medium_impact	1,03	medium_impact	0,08	medium_impact	0,23	0,7	0,85	24,34	21,11	N	0,5	N	0,44	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14306	14306	C	G	MI.23423	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	368	123	S	T	aGc/aCc	-0,29	0	0	benign	0,22	neutral	0,41	neutral	2,21	deleterious	-3,46	neutral	-1,14	medium_impact	2,06	neutral	0,79	neutral	0,71	deleterious	1,99	16,13	0,26	0,45	neutral	0,26	neutral	0,48	neutral	0,44	neutral	0,47	1	neutral	0,5	deleterious	0,6	neutral	-3	neutral	0,36	medium_impact	-0,29	medium_impact	0,12	medium_impact	0,59	0,84	0,9	24,34	21,11	N	0,41	N	0,41	NA	NA	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14306	14306	C	A	MI.23424	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	368	123	S	I	aGc/aTc	-0,29	0	0	possibly_damaging	0,71	neutral	0,45	neutral	2,17	deleterious	-4,77	deleterious	-2,97	medium_impact	2,25	neutral	0,77	neutral	0,61	deleterious	4,59	24,4	0,35	0,5	neutral	0,43	disease	0,79	neutral	0,48	disease	0,67	3	neutral	0,7	neutral	0,37	NA	0	deleterious	0,66	low_impact	-1,15	medium_impact	0,16	medium_impact	0,75	0,89	0,9	24,34	21,11	N	0,38	N	0,83	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14307	14307	T	C	MI.23425	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	367	123	S	G	Agc/Ggc	-2,35	0	0	benign	0,01	neutral	0,39	neutral	2,19	deleterious	-3,71	neutral	-0,94	neutral_impact	0,76	neutral	0,93	neutral	0,91	deleterious	0,18	4,42	0,3	0,45	neutral	0,33	neutral	0,36	neutral	0,35	neutral	0,46	1	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,14	medium_impact	1,03	medium_impact	0,1	medium_impact	-0,5	0,84	0,9	24,34	21,11	N	0,5	N	0,42	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14307	14307	T	A	MI.23426	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	367	123	S	C	Agc/Tgc	-2,35	0	0	probably_damaging	0,91	neutral	0,17	neutral	2,14	deleterious	-5,59	deleterious	-3,12	medium_impact	2,06	neutral	0,79	neutral	0,64	deleterious	3,69	23,3	0,3	0,45	disease	0,66	disease	0,73	neutral	0,39	disease	0,62	2	neutral	0,95	neutral	0,13	deleterious	1	deleterious	0,75	low_impact	-1,72	medium_impact	-0,18	medium_impact	0,59	0,87	0,9	24,34	21,11	N	0,42	N	0,69	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14307	14307	T	G	MI.23427	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	367	123	S	R	Agc/Cgc	-2,35	0	0	possibly_damaging	0,52	neutral	0,35	neutral	2,18	deleterious	-4,42	neutral	-1,8	medium_impact	2,6	neutral	0,75	neutral	0,45	deleterious	3,96	23,6	0,22	0,45	neutral	0,3	disease	0,77	disease	0,53	disease	0,71	4	neutral	0,64	neutral	0,42	NA	0	deleterious	0,53	medium_impact	-0,83	medium_impact	0,06	medium_impact	1,04	0,87	0,9	24,34	21,11	N	0,42	N	0,65	NA	NA	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14309	14309	C	G	MI.23428	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	365	122	G	A	gGa/gCa	-6,94	0	0	benign	0,15	neutral	0,56	neutral	2,33	deleterious	-4,4	deleterious	-3,55	low_impact	1,55	neutral	0,82	neutral	0,66	deleterious	2,21	17,59	0,4	0,5	neutral	0,26	disease	0,84	neutral	0,44	disease	0,59	2	neutral	0,34	deleterious	0,71	neutral	-6	neutral	0,29	medium_impact	-0,11	medium_impact	0,27	medium_impact	0,16	0,84	0,9	47,35	8,39	N	0,33	N	0,79	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14309	14309	C	A	MI.23429	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	365	122	G	V	gGa/gTa	-6,94	0	0	possibly_damaging	0,85	neutral	0,52	neutral	2,27	deleterious	-5,73	deleterious	-5,78	medium_impact	2,25	neutral	0,8	neutral	0,67	deleterious	4,21	23,9	0,24	0,45	neutral	0,25	disease	0,91	neutral	0,44	disease	0,59	2	neutral	0,83	neutral	0,34	NA	0	deleterious	0,76	low_impact	-1,49	medium_impact	0,23	medium_impact	0,75	0,87	0,9	47,35	8,39	N	0,34	N	0,96	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6120	6120	A	C	MI.2343	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	217	73	I	L	Atc/Ctc	-12,6	0	0	probably_damaging	0,98	neutral	0,11	neutral	2,85	neutral	0,42	neutral	-1,09	medium_impact	2,2	neutral	0,63	neutral	0,51	deleterious	3,65	23,2	0,36	0,55	neutral	0,25	disease	0,62	neutral	0,43	neutral	0,47	1	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,64	low_impact	-2,35	medium_impact	-0,31	medium_impact	0,93	0,73	0,9	5,65	37,31	N	0,5	N	0,25	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14309	14309	C	T	MI.23430	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	365	122	G	E	gGa/gAa	-6,94	0	0	possibly_damaging	0,89	neutral	0,36	neutral	2,41	deleterious	-5,32	deleterious	-3,36	low_impact	1,27	neutral	0,9	neutral	0,85	neutral	1,01	10,74	0,36	0,5	neutral	0,38	disease	0,87	disease	0,51	disease	0,58	2	neutral	0,89	neutral	0,24	neutral	-3	deleterious	0,8	low_impact	-1,63	medium_impact	0,07	medium_impact	-0,08	0,81	0,85	47,35	8,39	N	0,33	N	0,99	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14310	14310	C	G	MI.23431	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	364	122	G	R	Gga/Cga	-0,29	0	0	probably_damaging	0,96	neutral	0,37	neutral	2,28	deleterious	-5,95	deleterious	-4,79	medium_impact	3,22	neutral	0,75	damaging	0,23	deleterious	4,14	23,8	0,27	0,45	neutral	0,43	disease	0,91	disease	0,6	disease	0,76	5	neutral	0,96	neutral	0,21	deleterious	1	deleterious	0,83	low_impact	-2,06	medium_impact	0,08	medium_impact	1,56	0,91	0,95	47,35	8,39	N	0,29	N	0,98	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14310	14310	C	A	MI.23432	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	364	122	G	W	Gga/Tga	-0,29	0	0	probably_damaging	0,99	neutral	0,19	neutral	2,24	deleterious	-8,54	deleterious	-5,68	medium_impact	3,22	neutral	0,77	damaging	0,26	deleterious	4,79	24,7	0,22	0,45	disease	0,72	disease	0,93	disease	0,56	disease	0,76	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,86	low_impact	-2,63	medium_impact	-0,14	medium_impact	1,56	0,69	0,85	47,35	8,39	N	0,29	N	0,99	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14312	14312	A	C	MI.23433	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	362	121	V	G	gTa/gGa	-8,31	0	0	benign	0,3	neutral	0,42	neutral	2,2	deleterious	-5,02	deleterious	-4	low_impact	0,94	neutral	0,79	neutral	0,76	neutral	1,79	14,9	0,24	0,45	neutral	0,43	disease	0,61	neutral	0,46	neutral	0,48	0	neutral	0,49	deleterious	0,56	neutral	-6	neutral	0,33	medium_impact	-0,46	medium_impact	0,13	medium_impact	-0,35	0,65	0,8	23,01	21,88	N	0,31	N	0,81	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14312	14312	A	T	MI.23434	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	362	121	V	E	gTa/gAa	-8,31	0	0	possibly_damaging	0,5	neutral	0,46	neutral	2,21	deleterious	-5,19	deleterious	-3,42	low_impact	1,13	neutral	0,9	neutral	0,86	neutral	1,54	13,5	0,27	0,45	neutral	0,16	disease	0,77	neutral	0,42	disease	0,61	2	neutral	0,53	deleterious	0,48	neutral	-3	neutral	0,43	medium_impact	-0,8	medium_impact	0,17	medium_impact	-0,19	0,7	0,85	23,01	21,88	N	0,31	N	0,83	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14312	14312	A	G	MI.23435	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	362	121	V	A	gTa/gCa	-8,31	0	0	benign	0,01	neutral	0,64	neutral	2,24	deleterious	-3,61	neutral	-1,69	low_impact	0,94	neutral	0,91	neutral	0,98	deleterious	0,6	8,14	0,42	0,55	neutral	0,2	neutral	0,48	disease	0,51	neutral	0,44	1	neutral	0,34	deleterious	0,82	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	0,35	medium_impact	-0,35	0,73	0,85	23,01	21,88	N	0,32	N	0,4	NA	NA	0,28	.	.	.	.	.	.	COSM1138260	.	.	.	.	.	.	.	.
chrM	14313	14313	C	G	MI.23436	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	361	121	V	L	Gta/Cta	-0,29	0	0	benign	0,05	neutral	0,72	neutral	2,34	neutral	-2,68	neutral	0,59	neutral_impact	0,42	neutral	0,89	neutral	0,96	neutral	-0,82	0,04	0,44	0,55	neutral	0,11	neutral	0,27	neutral	0,36	neutral	0,42	2	neutral	0,2	deleterious	0,84	neutral	-6	neutral	0,11	medium_impact	0,38	medium_impact	0,43	medium_impact	-0,79	0,87	0,9	23,01	21,88	N	0,33	N	0,4	NA	NA	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14313	14313	C	A	MI.23437	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	361	121	V	L	Gta/Tta	-0,29	0	0	benign	0,05	neutral	0,72	neutral	2,34	neutral	-2,68	neutral	0,59	neutral_impact	0,42	neutral	0,89	neutral	0,96	neutral	-0,51	0,21	0,44	0,55	neutral	0,11	neutral	0,27	neutral	0,36	neutral	0,42	2	neutral	0,2	deleterious	0,84	neutral	-6	neutral	0,11	medium_impact	0,38	medium_impact	0,43	medium_impact	-0,79	0,87	0,9	23,01	21,88	N	0,4	N	0,4	NA	NA	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14313	14313	C	T	MI.23438	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	361	121	V	M	Gta/Ata	-0,29	0	0	benign	0,04	neutral	0,24	neutral	2,23	deleterious	-4,64	neutral	1,04	neutral_impact	-0,2	neutral	0,97	neutral	0,95	neutral	-0,54	0,18	0,48	0,55	neutral	0,29	neutral	0,22	neutral	0,38	neutral	0,4	2	neutral	0,74	deleterious	0,6	neutral	-6	neutral	0,12	medium_impact	0,47	medium_impact	-0,07	low_impact	-1,31	0,84	0,9	23,01	21,88	P	0,57	P	0,29	NA	NA	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14315	14315	C	G	MI.23439	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	359	120	S	T	aGt/aCt	-2,81	0	0	benign	0,01	neutral	0,41	neutral	2,24	deleterious	-3,46	neutral	-1,55	low_impact	0,9	neutral	0,94	neutral	0,95	deleterious	0,8	9,47	0,24	0,45	neutral	0,25	neutral	0,31	neutral	0,47	neutral	0,45	1	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,14	medium_impact	1,03	medium_impact	0,12	medium_impact	-0,39	0,68	0,85	50,44	8,68	N	0,46	N	0,28	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6120	6120	A	T	MI.2344	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	217	73	I	F	Atc/Ttc	-12,6	0	0	probably_damaging	1	neutral	0,06	neutral	2,88	neutral	0,6	neutral	-2,29	medium_impact	2,04	damaging	0,59	neutral	0,52	deleterious	3,79	23,4	0,38	0,55	neutral	0,4	disease	0,75	neutral	0,34	disease	0,55	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,76	low_impact	-3,58	medium_impact	-0,47	medium_impact	0,79	0,8	0,9	5,65	37,31	N	0,43	N	0,57	polymorphism	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14315	14315	C	T	MI.23440	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	359	120	S	N	aGt/aAt	-2,81	0	0	benign	0	neutral	0,35	neutral	2,29	deleterious	-4,18	neutral	0,27	neutral_impact	0,49	neutral	0,95	neutral	0,98	deleterious	0,37	6,35	0,54	0,6	neutral	0,27	neutral	0,39	neutral	0,37	neutral	0,44	1	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,14	medium_impact	1,95	medium_impact	0,06	medium_impact	-0,73	0,7	0,85	50,44	8,68	N	0,52	P	0,05	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14315	14315	C	A	MI.23441	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	359	120	S	I	aGt/aTt	-2,81	0	0	benign	0,4	neutral	0,41	neutral	2,34	deleterious	-4,77	deleterious	-3,88	low_impact	1,59	neutral	0,85	neutral	0,72	deleterious	4,4	24,1	0,33	0,5	neutral	0,45	disease	0,7	disease	0,55	disease	0,68	4	neutral	0,53	deleterious	0,51	neutral	-6	neutral	0,37	medium_impact	-0,64	medium_impact	0,12	medium_impact	0,19	0,85	0,9	50,44	8,68	N	0,35	N	0,74	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14316	14316	T	A	MI.23442	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	358	120	S	C	Agt/Tgt	-2,81	0	0	possibly_damaging	0,86	neutral	0,18	neutral	2,16	deleterious	-5,59	deleterious	-3,46	low_impact	1,94	neutral	0,86	neutral	0,74	deleterious	3,81	23,4	0,29	0,45	disease	0,63	disease	0,67	neutral	0,43	disease	0,53	1	neutral	0,92	neutral	0,16	neutral	-3	deleterious	0,69	low_impact	-1,52	medium_impact	-0,16	medium_impact	0,49	0,78	0,85	50,44	8,68	N	0,44	N	0,57	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14316	14316	T	G	MI.23443	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	358	120	S	R	Agt/Cgt	-2,81	0	0	benign	0,21	neutral	0,36	neutral	2,2	deleterious	-4,42	neutral	-2,16	medium_impact	2,29	neutral	0,77	neutral	0,56	deleterious	3,77	23,4	0,28	0,45	neutral	0,26	disease	0,69	disease	0,58	disease	0,72	4	neutral	0,57	deleterious	0,58	neutral	-3	neutral	0,3	medium_impact	-0,27	medium_impact	0,07	medium_impact	0,78	0,85	0,9	50,44	8,68	N	0,37	N	0,6	NA	NA	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14316	14316	T	C	MI.23444	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	358	120	S	G	Agt/Ggt	-2,81	0	0	benign	0,14	neutral	0,36	neutral	2,24	deleterious	-3,71	neutral	0,5	neutral_impact	0,16	neutral	0,88	neutral	1	neutral	-0,87	0,03	0,27	0,45	neutral	0,09	neutral	0,16	neutral	0,31	neutral	0,23	5	neutral	0,58	deleterious	0,61	neutral	-6	neutral	0,13	medium_impact	-0,07	medium_impact	0,07	low_impact	-1,01	0,68	0,85	50,44	8,68	N	0,43	N	0,09	NA	NA	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14317	14317	A	T	MI.23445	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	357	119	N	K	aaT/aaA	-4,87	0	0	benign	0,02	neutral	0,32	neutral	2,1	deleterious	-3,49	neutral	-2,28	neutral_impact	0,46	neutral	0,95	neutral	0,78	neutral	0,92	10,2	0,62	0,65	neutral	0,14	disease	0,58	neutral	0,46	neutral	0,44	1	neutral	0,67	deleterious	0,65	neutral	-6	neutral	0,14	medium_impact	0,75	medium_impact	0,03	medium_impact	-0,76	0,64	0,8	24,34	26,09	N	0,43	N	0,59	NA	NA	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14317	14317	A	C	MI.23446	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	357	119	N	K	aaT/aaG	-4,87	0	0	benign	0,02	neutral	0,32	neutral	2,1	deleterious	-3,49	neutral	-2,28	neutral_impact	0,46	neutral	0,95	neutral	0,78	deleterious	0,57	7,94	0,62	0,65	neutral	0,14	disease	0,58	neutral	0,46	neutral	0,44	1	neutral	0,67	deleterious	0,65	neutral	-6	neutral	0,14	medium_impact	0,75	medium_impact	0,03	medium_impact	-0,76	0,64	0,8	24,34	26,09	N	0,43	N	0,59	NA	NA	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14318	14318	T	C	MI.23447	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	356	119	N	S	aAt/aGt	-0,29	0	0,02	benign	0,02	neutral	0,44	neutral	2,17	deleterious	-3,41	neutral	-1,98	neutral_impact	0,66	neutral	0,93	neutral	0,96	neutral	-0,55	0,17	0,48	0,55	neutral	0,1	neutral	0,47	neutral	0,42	neutral	0,44	1	neutral	0,54	deleterious	0,71	neutral	-6	neutral	0,12	medium_impact	0,75	medium_impact	0,15	medium_impact	-0,59	0,36	0,8	24,34	26,09	N	0,41	N	0,1	NA	NA	0,31	rs28357675	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14318	14318	T	A	MI.23448	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	356	119	N	I	aAt/aTt	-0,29	0	0,02	possibly_damaging	0,76	neutral	0,41	neutral	2,06	deleterious	-4,99	deleterious	-5,2	low_impact	1,74	neutral	0,78	neutral	0,65	deleterious	2,95	22	0,26	0,45	neutral	0,28	disease	0,75	disease	0,54	disease	0,69	4	neutral	0,76	neutral	0,33	neutral	-3	deleterious	0,57	low_impact	-1,26	medium_impact	0,12	medium_impact	0,32	0,41	0,8	24,34	26,09	N	0,27	N	0,79	NA	NA	0,53	rs28357675	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14318	14318	T	G	MI.23449	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	356	119	N	T	aAt/aCt	-0,29	0	0,02	benign	0,2	neutral	0,41	neutral	2,1	deleterious	-3,9	deleterious	-3,15	medium_impact	1,99	neutral	0,82	neutral	0,73	deleterious	0,87	9,9	0,38	0,5	neutral	0,19	disease	0,57	disease	0,53	disease	0,62	2	neutral	0,51	deleterious	0,61	neutral	-3	neutral	0,28	medium_impact	-0,24	medium_impact	0,12	medium_impact	0,53	0,5	0,8	24,34	26,09	N	0,39	N	0,18	NA	NA	0,56	rs28357675	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6121	6121	T	G	MI.2345	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	218	73	I	S	aTc/aGc	3,13	0,99	0	probably_damaging	1	deleterious	0,04	neutral	2,72	neutral	-1,39	deleterious	-3,6	medium_impact	3,23	neutral	0,65	neutral	0,44	deleterious	4,19	23,8	0,27	0,55	neutral	0,36	disease	0,79	neutral	0,49	disease	0,61	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,73	low_impact	-3,58	medium_impact	-0,58	medium_impact	1,88	0,68	0,9	5,65	37,31	N	0,45	N	0,58	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14319	14319	T	A	MI.23450	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	355	119	N	Y	Aat/Tat	-2,12	0	0,01	possibly_damaging	0,86	neutral	1	neutral	2,03	deleterious	-5,29	deleterious	-3,86	low_impact	1,09	neutral	0,9	neutral	0,85	deleterious	2,44	19,08	0,32	0,5	neutral	0,37	disease	0,7	neutral	0,44	disease	0,58	2	neutral	0,86	deleterious	0,57	neutral	-3	deleterious	0,65	low_impact	-1,52	high_impact	1,87	medium_impact	-0,23	0,63	0,8	24,34	26,09	N	0,31	N	0,3	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14319	14319	T	C	MI.23451	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	355	119	N	D	Aat/Gat	-2,12	0	0,01	benign	0,01	neutral	0,23	neutral	2,06	deleterious	-3,24	neutral	-1,82	neutral_impact	0,4	neutral	0,94	neutral	0,97	deleterious	0,07	3,27	0,57	0,65	neutral	0,14	neutral	0,34	neutral	0,43	neutral	0,44	1	neutral	0,77	deleterious	0,61	neutral	-6	neutral	0,1	medium_impact	1,03	medium_impact	-0,09	medium_impact	-0,81	0,57	0,8	24,34	26,09	P	0,61	P	0,2	NA	NA	0,37	rs199476110	other	Parkinson_disease_6,_autosomal_recessive_early-onset	RCV000010335.3	MedGen:OMIM	.	.	CPD	0,15	T14319C	PD,early onset	+	-	Reported	2
chrM	14319	14319	T	G	MI.23452	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	355	119	N	H	Aat/Cat	-2,12	0	0,01	possibly_damaging	0,81	neutral	0,54	neutral	2,03	deleterious	-5,1	deleterious	-2,55	low_impact	1,74	neutral	0,85	neutral	0,7	deleterious	2	16,23	0,44	0,55	neutral	0,32	disease	0,58	neutral	0,49	disease	0,5	0	neutral	0,78	neutral	0,37	neutral	-3	deleterious	0,6	low_impact	-1,37	medium_impact	0,25	medium_impact	0,32	0,56	0,8	24,34	26,09	N	0,24	N	0,35	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14320	14320	A	C	MI.23453	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	354	118	F	L	ttT/ttG	-0,29	0	0	benign	0,02	neutral	0,72	neutral	2,44	neutral	-2,75	deleterious	-3,86	neutral_impact	0,56	neutral	0,93	neutral	0,82	deleterious	0,7	8,84	0,38	0,5	neutral	0,15	disease	0,76	disease	0,59	disease	0,59	2	neutral	0,25	deleterious	0,85	neutral	-6	neutral	0,17	medium_impact	0,75	medium_impact	0,43	medium_impact	-0,67	0,68	0,85	47,35	8,78	N	0,29	N	0,51	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14320	14320	A	T	MI.23454	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	354	118	F	L	ttT/ttA	-0,29	0	0	benign	0,02	neutral	0,72	neutral	2,44	neutral	-2,75	deleterious	-3,86	neutral_impact	0,56	neutral	0,93	neutral	0,82	deleterious	0,83	9,68	0,38	0,5	neutral	0,15	disease	0,76	disease	0,59	disease	0,59	2	neutral	0,25	deleterious	0,85	neutral	-6	neutral	0,17	medium_impact	0,75	medium_impact	0,43	medium_impact	-0,67	0,68	0,85	47,35	8,78	N	0,27	N	0,51	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14321	14321	A	G	MI.23455	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	353	118	F	S	tTt/tCt	-0,06	0	0	possibly_damaging	0,82	neutral	0,55	neutral	2,33	deleterious	-4,91	deleterious	-6,29	medium_impact	2,1	neutral	0,84	neutral	0,81	deleterious	3,15	22,6	0,34	0,5	neutral	0,4	disease	0,9	disease	0,64	disease	0,6	2	neutral	0,79	neutral	0,37	NA	0	deleterious	0,68	low_impact	-1,4	medium_impact	0,26	medium_impact	0,62	0,62	0,8	47,35	8,78	N	0,32	N	0,92	NA	NA	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14321	14321	A	T	MI.23456	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	353	118	F	Y	tTt/tAt	-0,06	0	0	benign	0,03	neutral	1	neutral	2,31	deleterious	-3,12	neutral	-1,97	low_impact	0,96	neutral	0,93	neutral	0,87	deleterious	0,7	8,83	0,33	0,5	neutral	0,43	disease	0,81	disease	0,61	disease	0,6	2	neutral	0,03	deleterious	0,99	neutral	-6	neutral	0,26	medium_impact	0,59	high_impact	1,87	medium_impact	-0,34	0,56	0,8	47,35	8,78	N	0,33	N	0,77	NA	NA	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14321	14321	A	C	MI.23457	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	353	118	F	C	tTt/tGt	-0,06	0	0	probably_damaging	0,96	neutral	0,18	neutral	2,26	deleterious	-6,52	deleterious	-5,55	medium_impact	2,2	neutral	0,87	neutral	0,79	deleterious	3,7	23,3	0,26	0,45	disease	0,61	disease	0,93	disease	0,64	disease	0,62	2	neutral	0,97	neutral	0,11	deleterious	1	deleterious	0,81	low_impact	-2,06	medium_impact	-0,16	medium_impact	0,7	0,5	0,8	47,35	8,78	N	0,38	N	0,55	NA	NA	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14322	14322	A	C	MI.23458	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	352	118	F	V	Ttt/Gtt	0,63	0,07	0	benign	0,37	neutral	0,59	neutral	2,34	deleterious	-3,78	deleterious	-4,97	low_impact	1,58	neutral	0,84	neutral	0,83	deleterious	2,09	16,78	0,3	0,45	neutral	0,14	disease	0,87	disease	0,61	disease	0,59	2	neutral	0,35	deleterious	0,61	neutral	-6	neutral	0,36	medium_impact	-0,58	medium_impact	0,29	medium_impact	0,18	0,7	0,85	47,35	8,78	N	0,28	N	0,83	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14322	14322	A	T	MI.23459	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	352	118	F	I	Ttt/Att	0,63	0,07	0	benign	0,26	neutral	0,43	neutral	2,32	deleterious	-3,78	deleterious	-4,13	low_impact	1,85	neutral	0,85	neutral	0,83	deleterious	2,37	18,6	0,31	0,45	neutral	0,2	disease	0,86	disease	0,62	disease	0,59	2	neutral	0,48	deleterious	0,59	neutral	-6	neutral	0,43	medium_impact	-0,38	medium_impact	0,14	medium_impact	0,41	0,61	0,8	47,35	8,78	N	0,4	N	0,82	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6121	6121	T	A	MI.2346	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	218	73	I	N	aTc/aAc	3,13	0,99	0	probably_damaging	1	deleterious	0	neutral	2,68	deleterious	-3,05	deleterious	-4,26	high_impact	3,78	neutral	0,64	neutral	0,4	deleterious	4,32	24	0,27	0,55	disease	0,6	disease	0,79	neutral	0,49	disease	0,64	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,39	0,65	0,9	5,65	37,31	N	0,48	N	0,77	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14322	14322	A	G	MI.23460	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	352	118	F	L	Ttt/Ctt	0,63	0,07	0	benign	0,02	neutral	0,72	neutral	2,44	neutral	-2,75	deleterious	-3,86	neutral_impact	0,56	neutral	0,93	neutral	0,82	deleterious	0,72	8,97	0,38	0,5	neutral	0,15	disease	0,76	disease	0,59	disease	0,59	2	neutral	0,25	deleterious	0,85	neutral	-6	neutral	0,17	medium_impact	0,75	medium_impact	0,43	medium_impact	-0,67	0,68	0,85	47,35	8,78	N	0,32	N	0,51	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14323	14323	G	T	MI.23461	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	351	117	N	K	aaC/aaA	2,92	0,08	0	possibly_damaging	0,49	neutral	0,59	neutral	2,32	deleterious	-3,49	neutral	-0,6	low_impact	1,17	neutral	0,89	neutral	0,92	neutral	1,3	12,26	0,62	0,65	neutral	0,11	disease	0,56	neutral	0,47	neutral	0,42	2	neutral	0,44	deleterious	0,55	neutral	-3	neutral	0,4	medium_impact	-0,78	medium_impact	0,29	medium_impact	-0,16	0,77	0,85	22,57	16,62	N	0,38	N	0,21	NA	NA	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14323	14323	G	C	MI.23462	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	351	117	N	K	aaC/aaG	2,92	0,08	0	possibly_damaging	0,49	neutral	0,59	neutral	2,32	deleterious	-3,49	neutral	-0,6	low_impact	1,17	neutral	0,89	neutral	0,92	neutral	1,14	11,43	0,62	0,65	neutral	0,11	disease	0,56	neutral	0,47	neutral	0,42	2	neutral	0,44	deleterious	0,55	neutral	-3	neutral	0,4	medium_impact	-0,78	medium_impact	0,29	medium_impact	-0,16	0,77	0,85	22,57	16,62	N	0,33	N	0,21	NA	NA	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14324	14324	T	C	MI.23463	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	350	117	N	S	aAc/aGc	-2,81	0	0	benign	0,05	neutral	0,66	neutral	2,35	deleterious	-3,41	neutral	-0,69	neutral_impact	0,42	neutral	0,92	neutral	0,94	neutral	-0,89	0,03	0,61	0,65	neutral	0,19	neutral	0,42	neutral	0,44	neutral	0,45	1	neutral	0,27	deleterious	0,81	neutral	-6	neutral	0,14	medium_impact	0,38	medium_impact	0,37	medium_impact	-0,79	0,5	0,8	22,57	16,62	N	0,34	N	0,05	NA	NA	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14324	14324	T	G	MI.23464	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	350	117	N	T	aAc/aCc	-2,81	0	0	possibly_damaging	0,49	neutral	0,58	neutral	2,41	deleterious	-3,9	neutral	-1,78	medium_impact	1,98	neutral	0,83	neutral	0,79	deleterious	0,58	8,03	0,4	0,5	neutral	0,24	neutral	0,47	disease	0,54	neutral	0,46	1	neutral	0,44	deleterious	0,55	NA	0	neutral	0,4	medium_impact	-0,78	medium_impact	0,28	medium_impact	0,52	0,56	0,8	22,57	16,62	N	0,36	N	0,3	NA	NA	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14324	14324	T	A	MI.23465	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	350	117	N	I	aAc/aTc	-2,81	0	0	possibly_damaging	0,88	neutral	0,48	neutral	2,31	deleterious	-4,99	deleterious	-3,54	medium_impact	1,98	neutral	0,81	neutral	0,62	deleterious	3,3	22,9	0,3	0,45	neutral	0,47	disease	0,72	disease	0,57	disease	0,73	5	neutral	0,87	neutral	0,3	NA	0	deleterious	0,69	low_impact	-1,59	medium_impact	0,19	medium_impact	0,52	0,44	0,8	22,57	16,62	N	0,27	N	0,77	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14325	14325	T	G	MI.23466	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	349	117	N	H	Aac/Cac	-0,06	0	0,02	probably_damaging	0,91	neutral	0,56	neutral	2,23	deleterious	-5,1	neutral	-1,41	medium_impact	2,17	neutral	0,8	neutral	0,64	deleterious	2,26	17,87	0,46	0,55	neutral	0,36	disease	0,55	disease	0,62	disease	0,71	4	neutral	0,9	neutral	0,33	deleterious	1	deleterious	0,64	low_impact	-1,72	medium_impact	0,27	medium_impact	0,68	0,54	0,8	22,57	16,62	N	0,27	N	0,41	NA	NA	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14325	14325	T	A	MI.23467	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	349	117	N	Y	Aac/Tac	-0,06	0	0,02	probably_damaging	0,94	neutral	1	neutral	2,23	deleterious	-5,29	deleterious	-2,72	low_impact	1,83	neutral	0,88	neutral	0,83	deleterious	2,89	21,8	0,32	0,5	disease	0,5	disease	0,69	disease	0,55	disease	0,57	1	neutral	0,94	deleterious	0,53	neutral	-2	deleterious	0,72	low_impact	-1,89	high_impact	1,87	medium_impact	0,39	0,63	0,8	22,57	16,62	N	0,28	N	0,76	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14325	14325	T	C	MI.23468	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	349	117	N	D	Aac/Gac	-0,06	0	0,02	possibly_damaging	0,49	neutral	0,42	neutral	2,27	deleterious	-3,24	neutral	0,7	low_impact	0,96	neutral	0,91	neutral	0,98	deleterious	-0,04	2,18	0,59	0,65	neutral	0,08	neutral	0,34	neutral	0,44	neutral	0,43	1	neutral	0,56	neutral	0,47	neutral	-3	neutral	0,4	medium_impact	-0,78	medium_impact	0,13	medium_impact	-0,34	0,65	0,8	22,57	16,62	P	0,54	P	0,11	NA	NA	0,19	rs397515505	Pathogenic	Leber's_optic_atrophy	RCV000055700.1	MedGen:OMIM:SNOMED_CT	.	COSM1155553	CPD	0,89	T14325C	LHON	+	-	Reported	1
chrM	14327	14327	A	C	MI.23469	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	347	116	V	G	gTa/gGa	-3,96	0	0	possibly_damaging	0,79	neutral	0,43	neutral	2,29	deleterious	-5,02	deleterious	-3,25	medium_impact	2,01	neutral	0,84	neutral	0,78	deleterious	2,24	17,75	0,19	0,45	neutral	0,47	disease	0,62	disease	0,6	neutral	0,49	0	neutral	0,79	neutral	0,32	NA	0	deleterious	0,63	low_impact	-1,32	medium_impact	0,14	medium_impact	0,54	0,74	0,85	49,56	8,7	N	0,38	N	0,87	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6121	6121	T	C	MI.2347	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	218	73	I	T	aTc/aCc	3,13	0,99	0	probably_damaging	1	neutral	0,14	neutral	2,73	neutral	-1,12	deleterious	-2,95	medium_impact	2,34	neutral	0,61	neutral	0,47	deleterious	3,31	22,9	0,44	0,55	neutral	0,19	disease	0,66	neutral	0,37	neutral	0,46	1	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,71	low_impact	-3,58	medium_impact	-0,25	medium_impact	1,06	0,7	0,9	5,65	37,31	N	0,48	N	0,7	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14327	14327	A	G	MI.23470	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	347	116	V	A	gTa/gCa	-3,96	0	0	benign	0,34	neutral	0,64	neutral	2,37	deleterious	-3,61	neutral	-1,77	medium_impact	2,21	neutral	0,87	neutral	0,85	deleterious	0,65	8,47	0,34	0,5	neutral	0,24	disease	0,53	disease	0,56	neutral	0,45	1	neutral	0,29	deleterious	0,65	neutral	-3	neutral	0,29	medium_impact	-0,53	medium_impact	0,35	medium_impact	0,71	0,75	0,85	49,56	8,7	N	0,33	N	0,62	NA	NA	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14327	14327	A	T	MI.23471	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	347	116	V	E	gTa/gAa	-3,96	0	0	possibly_damaging	0,86	neutral	0,49	neutral	2,31	deleterious	-5,19	deleterious	-3,11	low_impact	1,41	neutral	0,88	neutral	0,87	deleterious	3,04	22,4	0,13	0,4	neutral	0,48	disease	0,78	disease	0,72	disease	0,64	3	neutral	0,85	neutral	0,32	neutral	-3	deleterious	0,69	low_impact	-1,52	medium_impact	0,2	medium_impact	0,04	0,78	0,85	49,56	8,7	N	0,33	N	0,88	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14328	14328	C	A	MI.23472	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	346	116	V	L	Gta/Tta	0,17	0	0	benign	0,02	neutral	0,77	neutral	2,42	neutral	-2,68	neutral	-0,35	neutral_impact	0,72	neutral	0,94	neutral	0,97	deleterious	-0,01	2,51	0,37	0,5	neutral	0,13	neutral	0,39	neutral	0,39	neutral	0,44	1	neutral	0,18	deleterious	0,88	neutral	-6	neutral	0,11	medium_impact	0,75	medium_impact	0,5	medium_impact	-0,54	0,84	0,9	49,56	8,7	N	0,39	N	0,31	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14328	14328	C	G	MI.23473	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	346	116	V	L	Gta/Cta	0,17	0	0	benign	0,02	neutral	0,77	neutral	2,42	neutral	-2,68	neutral	-0,35	neutral_impact	0,72	neutral	0,94	neutral	0,97	neutral	-0,29	0,69	0,37	0,5	neutral	0,13	neutral	0,39	neutral	0,39	neutral	0,44	1	neutral	0,18	deleterious	0,88	neutral	-6	neutral	0,11	medium_impact	0,75	medium_impact	0,5	medium_impact	-0,54	0,84	0,9	49,56	8,7	N	0,39	N	0,31	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14328	14328	C	T	MI.23474	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	346	116	V	M	Gta/Ata	0,17	0	0	benign	0,23	neutral	0,32	neutral	2,3	deleterious	-4,64	neutral	-0,48	low_impact	1,06	neutral	0,88	neutral	0,74	deleterious	2,62	20,3	0,35	0,5	neutral	0,3	neutral	0,36	neutral	0,48	neutral	0,46	1	neutral	0,61	deleterious	0,55	neutral	-6	neutral	0,17	medium_impact	-0,32	medium_impact	0,03	medium_impact	-0,25	0,83	0,85	49,56	8,7	N	0,48	N	0,55	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14330	14330	A	G	MI.23475	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	344	115	V	A	gTg/gCg	-12,9	0	0	benign	0	neutral	0,55	neutral	2,35	deleterious	-3,58	neutral	-2,03	low_impact	1,18	neutral	0,93	neutral	0,94	deleterious	0,65	8,49	0,31	0,5	neutral	0,18	disease	0,52	disease	0,57	neutral	0,46	1	neutral	0,44	deleterious	0,78	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,26	medium_impact	-0,15	0,67	0,85	21,24	12,41	N	0,39	N	0,71	NA	NA	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14330	14330	A	T	MI.23476	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	344	115	V	E	gTg/gAg	-12,9	0	0	benign	0,01	neutral	0,42	neutral	2,35	deleterious	-5,22	deleterious	-3,79	medium_impact	2,42	neutral	0,87	neutral	0,78	neutral	1,39	12,73	0,16	0,45	neutral	0,34	disease	0,8	disease	0,65	disease	0,63	3	neutral	0,57	deleterious	0,71	neutral	-3	neutral	0,22	medium_impact	1,03	medium_impact	0,13	medium_impact	0,89	0,77	0,85	21,24	12,41	N	0,37	N	0,94	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14330	14330	A	C	MI.23477	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	344	115	V	G	gTg/gGg	-12,9	0	0	benign	0,09	neutral	0,38	neutral	2,34	deleterious	-5,42	deleterious	-3,73	low_impact	1,62	neutral	0,89	neutral	0,96	deleterious	0,48	7,29	0,21	0,45	neutral	0,37	disease	0,6	disease	0,51	neutral	0,47	1	neutral	0,57	deleterious	0,65	neutral	-6	neutral	0,2	medium_impact	0,13	medium_impact	0,09	medium_impact	0,22	0,69	0,85	21,24	12,41	N	0,42	N	0,93	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14331	14331	C	A	MI.23478	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	343	115	V	L	Gtg/Ttg	0,17	0	0	benign	0,03	neutral	0,71	neutral	2,36	neutral	-0,99	neutral	-1,37	low_impact	1,53	neutral	0,88	neutral	0,93	deleterious	0,79	9,4	0,38	0,5	neutral	0,14	neutral	0,38	neutral	0,43	neutral	0,44	1	neutral	0,24	deleterious	0,84	neutral	-6	neutral	0,11	medium_impact	0,59	medium_impact	0,42	medium_impact	0,14	0,84	0,9	21,24	12,41	N	0,36	N	0,4	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14331	14331	C	T	MI.23479	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	343	115	V	M	Gtg/Atg	0,17	0	0	benign	0,02	neutral	0,27	neutral	2,3	deleterious	-3,82	neutral	-1,45	medium_impact	2,08	neutral	0,91	neutral	0,94	deleterious	0,83	9,63	0,39	0,5	neutral	0,27	neutral	0,33	neutral	0,46	neutral	0,46	1	neutral	0,72	deleterious	0,63	neutral	-3	neutral	0,12	medium_impact	0,75	medium_impact	-0,03	medium_impact	0,6	0,84	0,9	21,24	12,41	N	0,51	P	0,65	NA	NA	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6122	6122	C	G	MI.2348	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	219	73	I	M	atC/atG	7,53	1	0	probably_damaging	1	neutral	0,1	neutral	2,79	neutral	-0,21	neutral	-1,5	medium_impact	1,96	neutral	0,71	neutral	0,84	deleterious	2,13	17,03	0,49	0,55	neutral	0,41	neutral	0,5	neutral	0,3	neutral	0,47	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,7	low_impact	-3,58	medium_impact	-0,34	medium_impact	0,71	0,84	0,9	5,65	37,31	P	0,55	P	0,02	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14331	14331	C	G	MI.23480	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	343	115	V	L	Gtg/Ctg	0,17	0	0	benign	0,03	neutral	0,71	neutral	2,36	neutral	-0,99	neutral	-1,37	low_impact	1,53	neutral	0,88	neutral	0,93	deleterious	0,42	6,78	0,38	0,5	neutral	0,14	neutral	0,38	neutral	0,43	neutral	0,44	1	neutral	0,24	deleterious	0,84	neutral	-6	neutral	0,11	medium_impact	0,59	medium_impact	0,42	medium_impact	0,14	0,84	0,9	21,24	12,41	N	0,35	N	0,4	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14333	14333	A	G	MI.23481	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	341	114	V	A	gTt/gCt	-3,04	0	0	possibly_damaging	0,45	neutral	0,55	neutral	2,23	neutral	-0,03	neutral	-2,21	medium_impact	2,05	neutral	0,89	neutral	0,91	neutral	1,22	11,87	0,3	0,45	disease	0,51	neutral	0,42	disease	0,56	neutral	0,43	1	neutral	0,43	deleterious	0,55	NA	0	neutral	0,41	medium_impact	-0,72	medium_impact	0,26	medium_impact	0,58	0,74	0,85	18,14	12,08	N	0,4	N	0,7	NA	NA	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14333	14333	A	C	MI.23482	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	341	114	V	G	gTt/gGt	-3,04	0	0	possibly_damaging	0,88	neutral	0,36	neutral	2,35	neutral	-0,34	deleterious	-3,68	medium_impact	2,51	neutral	0,89	neutral	0,87	deleterious	2,64	20,5	0,2	0,45	disease	0,79	neutral	0,5	disease	0,6	disease	0,57	1	neutral	0,88	neutral	0,24	NA	0	deleterious	0,71	low_impact	-1,59	medium_impact	0,07	medium_impact	0,96	0,76	0,85	18,14	12,08	N	0,44	N	0,91	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14333	14333	A	T	MI.23483	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	341	114	V	D	gTt/gAt	-3,04	0	0	probably_damaging	0,93	neutral	0,24	neutral	2,23	neutral	-0,67	deleterious	-3,81	medium_impact	2,86	neutral	0,89	neutral	0,85	deleterious	3,46	23	0,14	0,4	disease	0,85	disease	0,71	disease	0,69	disease	0,71	4	neutral	0,95	neutral	0,16	deleterious	1	deleterious	0,76	low_impact	-1,83	medium_impact	-0,07	medium_impact	1,26	0,79	0,85	18,14	12,08	N	0,45	N	0,94	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14334	14334	C	G	MI.23484	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	340	114	V	L	Gtt/Ctt	1,31	0	0	benign	0,21	neutral	0,68	neutral	2,38	neutral	-0,33	neutral	-0,58	low_impact	1,34	neutral	0,88	neutral	0,89	neutral	-0,07	1,95	0,39	0,5	neutral	0,22	neutral	0,28	neutral	0,38	neutral	0,43	1	neutral	0,21	deleterious	0,74	neutral	-6	neutral	0,19	medium_impact	-0,27	medium_impact	0,39	medium_impact	-0,02	0,87	0,9	18,14	12,08	N	0,35	N	0,67	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14334	14334	C	A	MI.23485	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	340	114	V	F	Gtt/Ttt	1,31	0	0	possibly_damaging	0,84	neutral	0,71	neutral	2,28	neutral	-2,45	neutral	-1,97	low_impact	1,7	neutral	0,89	neutral	0,89	deleterious	2,63	20,4	0,22	0,45	disease	0,57	disease	0,63	neutral	0,44	disease	0,52	0	neutral	0,81	neutral	0,44	neutral	-3	deleterious	0,66	low_impact	-1,46	medium_impact	0,42	medium_impact	0,28	0,78	0,85	18,14	12,08	N	0,32	N	0,86	NA	NA	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14334	14334	C	T	MI.23486	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	340	114	V	I	Gtt/Att	1,31	0	0	benign	0,1	neutral	0,41	neutral	2,32	neutral	-0,57	neutral	-0,05	low_impact	0,96	neutral	0,92	neutral	0,95	deleterious	0,54	7,72	0,42	0,55	neutral	0,2	neutral	0,18	neutral	0,4	neutral	0,35	3	neutral	0,53	deleterious	0,66	neutral	-6	neutral	0,12	medium_impact	0,08	medium_impact	0,12	medium_impact	-0,34	0,86	0,9	18,14	12,08	N	0,48	N	0,22	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14336	14336	A	C	MI.23487	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	338	113	V	G	gTg/gGg	-5,56	0	0	possibly_damaging	0,82	neutral	0,36	neutral	2,32	deleterious	-5,53	neutral	1,39	neutral_impact	0,61	neutral	0,92	neutral	0,91	deleterious	2,16	17,25	0,2	0,45	neutral	0,2	disease	0,52	neutral	0,42	neutral	0,44	1	neutral	0,83	neutral	0,27	neutral	-3	deleterious	0,55	low_impact	-1,4	medium_impact	0,07	medium_impact	-0,63	0,74	0,85	42,04	7,9	N	0,38	N	0,45	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14336	14336	A	T	MI.23488	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	338	113	V	E	gTg/gAg	-5,56	0	0	benign	0,02	neutral	0,34	neutral	2,34	deleterious	-5,46	neutral	4,05	neutral_impact	-0,2	neutral	0,95	neutral	0,93	deleterious	0,22	4,87	0,21	0,45	neutral	0,1	disease	0,64	neutral	0,44	neutral	0,44	1	neutral	0,65	deleterious	0,66	neutral	-6	neutral	0,14	medium_impact	0,75	medium_impact	0,05	low_impact	-1,31	0,75	0,85	42,04	7,9	N	0,35	N	0,12	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14336	14336	A	G	MI.23489	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	338	113	V	A	gTg/gCg	-5,56	0	0	possibly_damaging	0,46	neutral	0,56	neutral	2,33	deleterious	-3,78	neutral	1	medium_impact	2,08	neutral	0,88	neutral	0,88	deleterious	2	16,23	0,36	0,5	neutral	0,16	neutral	0,49	neutral	0,48	neutral	0,44	1	neutral	0,43	deleterious	0,55	NA	0	deleterious	0,44	medium_impact	-0,73	medium_impact	0,27	medium_impact	0,6	0,76	0,85	42,04	7,9	N	0,27	N	0,44	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6122	6122	C	A	MI.2349	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	219	73	I	M	atC/atA	7,53	1	0	probably_damaging	1	neutral	0,1	neutral	2,79	neutral	-0,21	neutral	-1,5	medium_impact	1,96	neutral	0,71	neutral	0,84	deleterious	2,65	20,5	0,49	0,55	neutral	0,41	neutral	0,5	neutral	0,3	neutral	0,47	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,7	low_impact	-3,58	medium_impact	-0,34	medium_impact	0,71	0,84	0,9	5,65	37,31	P	0,55	P	0,02	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14337	14337	C	G	MI.23490	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	337	113	V	L	Gtg/Ctg	-0,75	0	0	possibly_damaging	0,62	neutral	0,67	neutral	2,45	neutral	-2,17	neutral	-0,52	low_impact	1,1	neutral	0,92	neutral	0,89	deleterious	0,49	7,39	0,42	0,55	neutral	0,11	neutral	0,34	neutral	0,47	neutral	0,44	1	neutral	0,55	deleterious	0,53	neutral	-3	deleterious	0,46	medium_impact	-0,99	medium_impact	0,38	medium_impact	-0,22	0,85	0,9	42,04	7,9	N	0,35	N	0,62	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14337	14337	C	A	MI.23491	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	337	113	V	L	Gtg/Ttg	-0,75	0	0	possibly_damaging	0,62	neutral	0,67	neutral	2,45	neutral	-2,17	neutral	-0,52	low_impact	1,1	neutral	0,92	neutral	0,89	deleterious	0,83	9,64	0,42	0,55	neutral	0,11	neutral	0,34	neutral	0,47	neutral	0,44	1	neutral	0,55	deleterious	0,53	neutral	-3	deleterious	0,46	medium_impact	-0,99	medium_impact	0,38	medium_impact	-0,22	0,85	0,9	42,04	7,9	N	0,33	N	0,62	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14337	14337	C	T	MI.23492	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	337	113	V	M	Gtg/Atg	-0,75	0	0	probably_damaging	0,95	neutral	0,23	neutral	2,26	deleterious	-4,16	neutral	0,06	medium_impact	2,08	neutral	0,89	neutral	0,86	neutral	1,16	11,54	0,44	0,55	neutral	0,28	neutral	0,28	disease	0,52	neutral	0,46	1	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,64	low_impact	-1,97	medium_impact	-0,09	medium_impact	0,6	0,84	0,9	42,04	7,9	N	0,51	P	0,58	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14339	14339	A	G	MI.23493	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	335	112	V	A	gTg/gCg	-6,48	0	0	benign	0,03	neutral	0,56	neutral	2,35	neutral	-2,67	neutral	-2,12	low_impact	1,46	neutral	0,89	neutral	0,9	neutral	1,12	11,33	0,35	0,5	neutral	0,27	disease	0,5	disease	0,63	neutral	0,49	0	neutral	0,4	deleterious	0,77	neutral	-6	neutral	0,15	medium_impact	0,59	medium_impact	0,27	medium_impact	0,08	0,75	0,85	5,75	12,69	N	0,29	N	0,6	NA	NA	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14339	14339	A	C	MI.23494	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	335	112	V	G	gTg/gGg	-6,48	0	0	benign	0,37	neutral	0,37	neutral	2,33	deleterious	-4,41	deleterious	-3,81	low_impact	1,52	neutral	0,93	neutral	0,88	neutral	1,05	10,92	0,21	0,45	neutral	0,32	disease	0,57	disease	0,65	neutral	0,5	0	neutral	0,56	deleterious	0,5	neutral	-6	neutral	0,35	medium_impact	-0,58	medium_impact	0,08	medium_impact	0,13	0,75	0,85	5,75	12,69	N	0,41	N	0,85	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14339	14339	A	T	MI.23495	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	335	112	V	E	gTg/gAg	-6,48	0	0	possibly_damaging	0,5	neutral	0,36	neutral	2,35	deleterious	-4,46	deleterious	-2,6	low_impact	1,69	neutral	0,9	neutral	0,87	deleterious	1,98	16,07	0,23	0,45	neutral	0,24	disease	0,77	disease	0,78	disease	0,66	3	neutral	0,62	neutral	0,43	neutral	-3	deleterious	0,47	medium_impact	-0,8	medium_impact	0,07	medium_impact	0,28	0,7	0,85	5,75	12,69	N	0,41	N	0,9	NA	NA	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14340	14340	C	A	MI.23496	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	334	112	V	L	Gtg/Ttg	1,08	0	0	benign	0,01	neutral	0,67	neutral	2,34	neutral	-1,7	neutral	-0,44	neutral_impact	0,53	neutral	0,96	neutral	0,89	deleterious	0,26	5,31	0,45	0,55	neutral	0,19	neutral	0,35	neutral	0,44	neutral	0,44	1	neutral	0,31	deleterious	0,83	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,38	medium_impact	-0,7	0,87	0,9	5,75	12,69	N	0,36	N	0,55	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14340	14340	C	G	MI.23497	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	334	112	V	L	Gtg/Ctg	1,08	0	0	benign	0,01	neutral	0,67	neutral	2,34	neutral	-1,7	neutral	-0,44	neutral_impact	0,53	neutral	0,96	neutral	0,89	deleterious	-0,02	2,42	0,45	0,55	neutral	0,19	neutral	0,35	neutral	0,44	neutral	0,44	1	neutral	0,31	deleterious	0,83	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,38	medium_impact	-0,7	0,87	0,9	5,75	12,69	N	0,36	N	0,55	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14340	14340	C	T	MI.23498	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	334	112	V	M	Gtg/Atg	1,08	0	0	possibly_damaging	0,69	neutral	0,23	neutral	2,28	deleterious	-3,4	neutral	-0,9	low_impact	1,6	neutral	0,92	neutral	0,91	neutral	1,25	12,03	0,4	0,5	neutral	0,36	neutral	0,28	neutral	0,48	neutral	0,45	1	neutral	0,81	neutral	0,27	neutral	-3	deleterious	0,48	low_impact	-1,11	medium_impact	-0,09	medium_impact	0,2	0,86	0,9	5,75	12,69	P	0,66	P	0,02	NA	NA	0,28	.	.	.	.	.	.	.	CPD	0,74	C14340T	SNHL	+	-	Reported	1
chrM	14342	14342	C	T	MI.23499	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	332	111	G	E	gGg/gAg	-3,73	0	0	benign	0,01	neutral	0,29	neutral	2,28	neutral	0,52	neutral	0,09	neutral_impact	-0,72	neutral	0,95	neutral	0,91	neutral	-0,42	0,35	0,38	0,5	neutral	0,11	disease	0,71	neutral	0,5	disease	0,56	1	neutral	0,7	deleterious	0,64	neutral	-6	neutral	0,15	medium_impact	1,03	medium_impact	-0,01	low_impact	-1,74	0,75	0,85	14,6	14,23	N	0,39	N	0,19	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8636	8636	T	A	MI.235	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	110	37	L	H	cTc/cAc	0,59	0,38	0	probably_damaging	0,96	neutral	0,08	neutral	4,28	deleterious	-3,65	deleterious	-3,7	medium_impact	2,86	neutral	0,8	neutral	0,4	deleterious	3,83	23,4	0,28	0,65	disease	0,59	disease	0,7	disease	0,74	disease	0,77	5	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,78	low_impact	-2,07	medium_impact	-0,31	medium_impact	1,35	0,62	0,9	20,35	20,89	N	0,26	N	0,81	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6123	6123	A	G	MI.2350	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	220	74	M	V	Ata/Gta	-2,42	0	0	probably_damaging	0,94	neutral	0,05	neutral	2,79	neutral	0,7	neutral	-2,16	medium_impact	2,77	neutral	0,62	damaging	0,2	deleterious	2,68	20,7	0,43	0,55	neutral	0,28	disease	0,92	disease	0,6	disease	0,57	1	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,75	low_impact	-1,88	medium_impact	-0,52	medium_impact	1,46	0,62	0,9	5,65	8,41	N	0,31	N	0,88	polymorphism	0,66	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14342	14342	C	A	MI.23500	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	332	111	G	V	gGg/gTg	-3,73	0	0	benign	0,41	neutral	0,51	neutral	2,35	neutral	0,71	deleterious	-2,71	neutral_impact	0,57	neutral	0,89	neutral	0,89	deleterious	2,72	20,9	0,33	0,5	disease	0,51	disease	0,73	disease	0,51	disease	0,59	2	neutral	0,44	deleterious	0,55	neutral	-6	neutral	0,4	medium_impact	-0,65	medium_impact	0,22	medium_impact	-0,66	0,8	0,85	14,6	14,23	N	0,25	N	0,59	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14342	14342	C	G	MI.23501	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	332	111	G	A	gGg/gCg	-3,73	0	0	benign	0,3	neutral	0,51	neutral	2,3	neutral	1,4	neutral	-1,35	low_impact	1,47	neutral	0,84	neutral	0,88	neutral	1,09	11,15	0,37	0,5	neutral	0,31	disease	0,64	disease	0,53	neutral	0,49	0	neutral	0,39	deleterious	0,61	neutral	-6	neutral	0,28	medium_impact	-0,46	medium_impact	0,22	medium_impact	0,09	0,77	0,85	14,6	14,23	N	0,3	N	0,12	NA	NA	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14343	14343	C	A	MI.23502	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	331	111	G	W	Ggg/Tgg	-0,52	0	0	probably_damaging	0,97	neutral	0,19	neutral	2,25	neutral	-0,67	deleterious	-2,96	low_impact	1,47	neutral	0,82	neutral	0,84	deleterious	4,86	24,9	0,24	0,45	disease	0,87	disease	0,83	disease	0,7	disease	0,77	5	deleterious	0,98	neutral	0,11	neutral	-2	deleterious	0,79	low_impact	-2,18	medium_impact	-0,14	medium_impact	0,09	0,61	0,8	14,6	14,23	N	0,27	N	0,6	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14343	14343	C	G	MI.23503	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	331	111	G	R	Ggg/Cgg	-0,52	0	0	possibly_damaging	0,54	neutral	0,35	neutral	2,25	neutral	-0,96	neutral	-1,18	low_impact	1,47	neutral	0,79	neutral	0,75	deleterious	2,41	18,9	0,31	0,45	neutral	0,38	disease	0,81	disease	0,66	disease	0,75	5	neutral	0,65	neutral	0,41	neutral	-3	deleterious	0,47	medium_impact	-0,86	medium_impact	0,06	medium_impact	0,09	0,92	0,95	14,6	14,23	N	0,26	N	0,5	NA	NA	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14344	14344	A	C	MI.23504	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	330	110	D	E	gaT/gaG	-0,29	0	0	benign	0,3	neutral	0,27	neutral	2,28	neutral	-1,18	neutral	-0,75	neutral_impact	-0,34	neutral	0,94	neutral	0,96	neutral	-0,59	0,13	0,43	0,55	neutral	0,12	neutral	0,32	neutral	0,31	neutral	0,45	1	neutral	0,67	deleterious	0,49	neutral	-6	neutral	0,28	medium_impact	-0,46	medium_impact	-0,03	low_impact	-1,43	0,64	0,8	22,12	15,91	N	0,44	N	0,13	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14344	14344	A	T	MI.23505	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	330	110	D	E	gaT/gaA	-0,29	0	0	benign	0,3	neutral	0,27	neutral	2,28	neutral	-1,18	neutral	-0,75	neutral_impact	-0,34	neutral	0,94	neutral	0,96	neutral	-0,43	0,32	0,43	0,55	neutral	0,12	neutral	0,32	neutral	0,31	neutral	0,45	1	neutral	0,67	deleterious	0,49	neutral	-6	neutral	0,28	medium_impact	-0,46	medium_impact	-0,03	low_impact	-1,43	0,64	0,8	22,12	15,91	N	0,45	N	0,13	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14345	14345	T	C	MI.23506	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	329	110	D	G	gAt/gGt	-7,4	0	0	benign	0,02	neutral	0,35	neutral	2,26	neutral	-2,76	neutral	-1,29	neutral_impact	-1	neutral	0,96	neutral	0,97	deleterious	0,02	2,82	0,27	0,45	neutral	0,2	neutral	0,48	neutral	0,44	neutral	0,46	1	neutral	0,64	deleterious	0,67	neutral	-6	neutral	0,13	medium_impact	0,75	medium_impact	0,06	low_impact	-1,98	0,53	0,8	22,12	15,91	N	0,35	N	0,8	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14345	14345	T	A	MI.23507	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	329	110	D	V	gAt/gTt	-7,4	0	0	possibly_damaging	0,76	neutral	0,48	neutral	2,35	neutral	-2,71	deleterious	-4,33	low_impact	1,06	neutral	0,85	neutral	0,87	deleterious	2,62	20,3	0,27	0,45	neutral	0,31	disease	0,7	neutral	0,44	disease	0,58	2	neutral	0,74	neutral	0,36	neutral	-3	deleterious	0,58	low_impact	-1,26	medium_impact	0,19	medium_impact	-0,25	0,41	0,8	22,12	15,91	N	0,27	N	0,91	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14345	14345	T	G	MI.23508	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	329	110	D	A	gAt/gCt	-7,4	0	0	benign	0,3	neutral	0,47	neutral	2,3	neutral	-1,72	deleterious	-3,08	low_impact	1,26	neutral	0,87	neutral	0,88	deleterious	0,56	7,88	0,27	0,45	neutral	0,18	disease	0,68	disease	0,53	neutral	0,46	1	neutral	0,44	deleterious	0,59	neutral	-6	neutral	0,31	medium_impact	-0,46	medium_impact	0,18	medium_impact	-0,08	0,64	0,8	22,12	15,91	N	0,34	N	0,82	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14346	14346	C	T	MI.23509	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	328	110	D	N	Gat/Aat	-2,58	0	0	benign	0,02	neutral	0,35	neutral	2,25	neutral	-2,02	neutral	-1,72	low_impact	0,98	neutral	0,91	neutral	0,88	neutral	0,91	10,14	0,51	0,6	neutral	0,17	disease	0,51	neutral	0,34	neutral	0,45	1	neutral	0,64	deleterious	0,67	neutral	-6	neutral	0,13	medium_impact	0,75	medium_impact	0,06	medium_impact	-0,32	0,73	0,85	22,12	15,91	N	0,43	N	0,4	NA	NA	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6123	6123	A	T	MI.2351	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	220	74	M	L	Ata/Tta	-2,42	0	0	possibly_damaging	0,9	neutral	0,33	neutral	2,92	neutral	2,07	neutral	-1,35	low_impact	0,96	neutral	0,62	neutral	0,86	deleterious	2,15	17,16	0,47	0,55	neutral	0,22	disease	0,67	neutral	0,41	neutral	0,43	1	neutral	0,91	neutral	0,22	neutral	-3	deleterious	0,6	low_impact	-1,65	medium_impact	0,02	medium_impact	-0,21	0,62	0,9	5,65	8,41	N	0,39	N	0,61	polymorphism	0,71	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14346	14346	C	A	MI.23510	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	328	110	D	Y	Gat/Tat	-2,58	0	0	probably_damaging	0,91	neutral	1	neutral	2,25	deleterious	-3,72	deleterious	-4,14	low_impact	1,06	neutral	0,86	neutral	0,85	deleterious	3,03	22,3	0,25	0,45	neutral	0,45	disease	0,78	neutral	0,4	disease	0,6	2	neutral	0,91	deleterious	0,55	neutral	-2	deleterious	0,71	low_impact	-1,72	high_impact	1,87	medium_impact	-0,25	0,43	0,8	22,12	15,91	N	0,24	N	0,95	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14346	14346	C	G	MI.23511	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	328	110	D	H	Gat/Cat	-2,58	0	0	possibly_damaging	0,84	neutral	0,51	neutral	2,22	deleterious	-3,17	deleterious	-3,01	medium_impact	1,96	neutral	0,78	neutral	0,63	deleterious	2,48	19,34	0,34	0,5	neutral	0,34	disease	0,63	disease	0,56	disease	0,71	4	neutral	0,82	neutral	0,34	NA	0	deleterious	0,61	low_impact	-1,46	medium_impact	0,22	medium_impact	0,5	0,56	0,8	22,12	15,91	N	0,3	N	0,75	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14348	14348	T	C	MI.23512	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	326	109	Y	C	tAt/tGt	-1,44	0	0	benign	0	neutral	0,18	neutral	2,27	deleterious	-5,89	deleterious	-2,74	low_impact	0,87	neutral	0,92	neutral	0,73	deleterious	0,19	4,56	0,3	0,45	neutral	0,48	disease	0,77	disease	0,52	disease	0,68	4	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,18	medium_impact	1,95	medium_impact	-0,16	medium_impact	-0,41	0,16	0,8	49,12	8,75	N	0,49	N	0,74	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14348	14348	T	G	MI.23513	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	326	109	Y	S	tAt/tCt	-1,44	0	0	benign	0	neutral	0,42	neutral	2,33	deleterious	-4,37	neutral	-0,54	neutral_impact	0,02	neutral	0,94	neutral	0,94	deleterious	0,43	6,83	0,28	0,45	neutral	0,12	disease	0,65	disease	0,51	neutral	0,45	1	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,13	low_impact	-1,12	0,38	0,8	49,12	8,75	N	0,32	N	0,61	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14348	14348	T	A	MI.23514	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	326	109	Y	F	tAt/tTt	-1,44	0	0	benign	0	neutral	0,7	neutral	2,36	neutral	-1,27	neutral	-1,28	low_impact	0,87	neutral	0,94	neutral	0,9	neutral	-0,37	0,45	0,35	0,5	neutral	0,31	neutral	0,44	neutral	0,38	neutral	0,46	1	neutral	0,29	deleterious	0,85	neutral	-6	neutral	0,14	medium_impact	1,95	medium_impact	0,41	medium_impact	-0,41	0,39	0,8	49,12	8,75	N	0,33	N	0,43	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14349	14349	A	C	MI.23515	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	325	109	Y	D	Tat/Gat	-3,5	0	0	benign	0,09	neutral	0,22	neutral	2,26	deleterious	-5,81	neutral	-0,43	neutral_impact	-0,56	neutral	0,92	neutral	0,86	deleterious	0,37	6,32	0,3	0,45	neutral	0,1	disease	0,73	disease	0,64	disease	0,58	2	neutral	0,75	deleterious	0,57	neutral	-6	neutral	0,17	medium_impact	0,13	medium_impact	-0,1	low_impact	-1,61	0,39	0,8	49,12	8,75	N	0,35	N	0,13	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14349	14349	A	G	MI.23516	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	325	109	Y	H	Tat/Cat	-3,5	0	0	possibly_damaging	0,49	neutral	0,53	neutral	2,26	deleterious	-4,31	neutral	-0,33	low_impact	1,15	neutral	0,8	neutral	0,86	neutral	1,32	12,39	0,45	0,55	neutral	0,27	disease	0,62	disease	0,6	neutral	0,5	0	neutral	0,47	deleterious	0,52	neutral	-3	neutral	0,42	medium_impact	-0,78	medium_impact	0,24	medium_impact	-0,18	0,35	0,8	49,12	8,75	N	0,28	N	0,45	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14349	14349	A	T	MI.23517	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	325	109	Y	N	Tat/Aat	-3,5	0	0	benign	0	neutral	0,32	neutral	2,29	deleterious	-5	neutral	-0,05	neutral_impact	-0,06	neutral	0,91	neutral	0,72	deleterious	0,21	4,76	0,3	0,45	neutral	0,13	disease	0,64	disease	0,51	neutral	0,49	0	neutral	0,68	deleterious	0,66	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,03	low_impact	-1,19	0,28	0,8	49,12	8,75	N	0,33	N	0,36	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14350	14350	C	A	MI.23518	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	324	108	E	D	gaG/gaT	-1,21	0	0	benign	0	neutral	0,21	neutral	2,27	neutral	-2,51	neutral	-0,42	neutral_impact	-0,6	neutral	0,96	neutral	0,91	deleterious	0,86	9,82	0,33	0,5	neutral	0,23	neutral	0,25	neutral	0,34	neutral	0,43	1	neutral	0,79	deleterious	0,61	neutral	-6	neutral	0,1	medium_impact	1,95	medium_impact	-0,11	low_impact	-1,64	0,8	0,85	47,79	8,45	N	0,48	N	0,13	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14350	14350	C	G	MI.23519	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	324	108	E	D	gaG/gaC	-1,21	0	0	benign	0	neutral	0,21	neutral	2,27	neutral	-2,51	neutral	-0,42	neutral_impact	-0,6	neutral	0,96	neutral	0,91	deleterious	0,62	8,32	0,33	0,5	neutral	0,23	neutral	0,25	neutral	0,34	neutral	0,43	1	neutral	0,79	deleterious	0,61	neutral	-6	neutral	0,1	medium_impact	1,95	medium_impact	-0,11	low_impact	-1,64	0,8	0,85	47,79	8,45	N	0,52	P	0,13	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6123	6123	A	C	MI.2352	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	220	74	M	L	Ata/Cta	-2,42	0	0	possibly_damaging	0,9	neutral	0,33	neutral	2,92	neutral	2,07	neutral	-1,35	low_impact	0,96	neutral	0,62	neutral	0,86	deleterious	2,08	16,7	0,47	0,55	neutral	0,22	disease	0,67	neutral	0,41	neutral	0,43	1	neutral	0,91	neutral	0,22	neutral	-3	deleterious	0,6	low_impact	-1,65	medium_impact	0,02	medium_impact	-0,21	0,62	0,9	5,65	8,41	N	0,39	N	0,61	polymorphism	0,71	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14351	14351	T	A	MI.23520	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	323	108	E	V	gAg/gTg	-5,33	0	0	benign	0,18	neutral	0,51	neutral	2,32	neutral	-1,04	neutral	-0,75	neutral_impact	-0,1	neutral	0,9	neutral	0,93	neutral	1,18	11,64	0,25	0,45	neutral	0,14	neutral	0,37	disease	0,54	neutral	0,46	1	neutral	0,39	deleterious	0,67	neutral	-6	neutral	0,25	medium_impact	-0,19	medium_impact	0,22	low_impact	-1,22	0,72	0,85	47,79	8,45	N	0,31	N	0,31	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14351	14351	T	G	MI.23521	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	323	108	E	A	gAg/gCg	-5,33	0	0	benign	0,09	neutral	0,51	neutral	2,33	neutral	-1,67	neutral	-0,28	low_impact	1,15	neutral	0,86	neutral	0,88	deleterious	0,27	5,4	0,28	0,45	neutral	0,15	neutral	0,37	disease	0,53	neutral	0,46	1	neutral	0,42	deleterious	0,71	neutral	-6	neutral	0,15	medium_impact	0,13	medium_impact	0,22	medium_impact	-0,18	0,72	0,85	47,79	8,45	N	0,31	N	0,11	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14351	14351	T	C	MI.23522	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	323	108	E	G	gAg/gGg	-5,33	0	0	benign	0,14	neutral	0,35	neutral	2,29	deleterious	-3	neutral	-0,18	neutral_impact	-0,26	neutral	0,97	neutral	0,97	deleterious	0,73	9	0,35	0,5	neutral	0,18	neutral	0,22	neutral	0,5	neutral	0,36	3	neutral	0,59	deleterious	0,61	neutral	-6	neutral	0,18	medium_impact	-0,07	medium_impact	0,06	low_impact	-1,36	0,75	0,85	47,79	8,45	N	0,43	N	0,01	NA	NA	0,16	.	.	.	.	.	.	COSM1155555	.	.	.	.	.	.	.	.
chrM	14352	14352	C	T	MI.23523	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	322	108	E	K	Gag/Aag	-4,19	0	0	benign	0,14	neutral	0,3	neutral	2,32	neutral	-1,79	neutral	0,42	neutral_impact	-0,07	neutral	0,86	neutral	0,92	neutral	1,37	12,64	0,29	0,45	neutral	0,1	neutral	0,36	disease	0,54	neutral	0,46	1	neutral	0,65	deleterious	0,58	neutral	-6	neutral	0,23	medium_impact	-0,07	medium_impact	0	low_impact	-1,2	0,79	0,85	47,79	8,45	N	0,34	N	0,22	NA	NA	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14352	14352	C	G	MI.23524	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	322	108	E	Q	Gag/Cag	-4,19	0	0	benign	0,34	neutral	0,3	neutral	2,31	neutral	-2,29	neutral	-0,16	low_impact	1,15	neutral	0,86	neutral	0,78	deleterious	0,52	7,58	0,39	0,5	neutral	0,19	neutral	0,2	neutral	0,49	neutral	0,39	2	neutral	0,64	deleterious	0,48	neutral	-6	neutral	0,33	medium_impact	-0,53	medium_impact	0	medium_impact	-0,18	0,75	0,85	47,79	8,45	N	0,43	N	0,13	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14353	14353	T	A	MI.23525	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	321	107	K	N	aaA/aaT	-3,5	0	0	benign	0,14	neutral	0,33	neutral	2,32	neutral	-2,54	neutral	-0,23	neutral_impact	0,49	neutral	0,84	neutral	0,92	deleterious	0,88	9,98	0,55	0,6	neutral	0,14	neutral	0,24	neutral	0,3	neutral	0,42	2	neutral	0,61	deleterious	0,6	neutral	-6	neutral	0,21	medium_impact	-0,07	medium_impact	0,04	medium_impact	-0,73	0,74	0,85	48,67	8,6	N	0,44	N	0,27	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14353	14353	T	G	MI.23526	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	321	107	K	N	aaA/aaC	-3,5	0	0	benign	0,14	neutral	0,33	neutral	2,32	neutral	-2,54	neutral	-0,23	neutral_impact	0,49	neutral	0,84	neutral	0,92	deleterious	0,66	8,57	0,55	0,6	neutral	0,14	neutral	0,24	neutral	0,3	neutral	0,42	2	neutral	0,61	deleterious	0,6	neutral	-6	neutral	0,21	medium_impact	-0,07	medium_impact	0,04	medium_impact	-0,73	0,74	0,85	48,67	8,6	N	0,41	N	0,27	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14354	14354	T	A	MI.23527	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	320	107	K	M	aAa/aTa	-3,04	0	0	benign	0,04	neutral	0,22	neutral	2,36	deleterious	-3,8	neutral	2,27	neutral_impact	-0,9	neutral	0,91	neutral	0,91	neutral	0,89	10,04	0,24	0,45	neutral	0,4	neutral	0,15	neutral	0,3	neutral	0,32	4	neutral	0,77	deleterious	0,59	neutral	-6	neutral	0,17	medium_impact	0,47	medium_impact	-0,1	low_impact	-1,89	0,51	0,8	48,67	8,6	N	0,46	N	0,51	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14354	14354	T	G	MI.23528	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	320	107	K	T	aAa/aCa	-3,04	0	0	benign	0,14	neutral	0,41	neutral	2,35	neutral	-1,32	neutral	0,54	neutral_impact	0,34	neutral	0,81	neutral	0,8	deleterious	0,49	7,35	0,25	0,45	neutral	0,16	neutral	0,2	neutral	0,4	neutral	0,37	3	neutral	0,52	deleterious	0,64	neutral	-6	neutral	0,22	medium_impact	-0,07	medium_impact	0,12	medium_impact	-0,86	0,6	0,8	48,67	8,6	N	0,34	N	0,37	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14355	14355	T	G	MI.23529	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	319	107	K	Q	Aaa/Caa	-0,06	0	0	benign	0,34	neutral	0,31	neutral	2,3	neutral	-2,2	neutral	-0,1	low_impact	1,04	neutral	0,82	neutral	0,67	deleterious	0,6	8,18	0,4	0,5	neutral	0,19	neutral	0,19	neutral	0,4	neutral	0,38	2	neutral	0,63	deleterious	0,49	neutral	-6	neutral	0,36	medium_impact	-0,53	medium_impact	0,01	medium_impact	-0,27	0,71	0,85	48,67	8,6	N	0,43	N	0,5	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6124	6124	T	A	MI.2353	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	221	74	M	K	aTa/aAa	6,83	1	0	probably_damaging	1	deleterious	0	neutral	2,68	neutral	-1,79	deleterious	-3,66	high_impact	4,72	damaging	0,59	damaging	0,11	deleterious	3,9	23,5	0,23	0,55	disease	0,59	disease	0,97	disease	0,73	disease	0,89	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,26	0,72	0,9	5,65	8,41	P	0,71	P	0,93	disease_causing	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14355	14355	T	C	MI.23530	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	319	107	K	E	Aaa/Gaa	-0,06	0	0	benign	0,14	neutral	0,31	neutral	2,31	neutral	-1,8	neutral	-0,5	neutral_impact	0,69	neutral	0,88	neutral	0,88	deleterious	0,52	7,6	0,32	0,5	neutral	0,15	neutral	0,41	neutral	0,35	neutral	0,43	1	neutral	0,64	deleterious	0,59	neutral	-6	neutral	0,23	medium_impact	-0,07	medium_impact	0,01	medium_impact	-0,56	0,76	0,85	48,67	8,6	N	0,42	N	0,54	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14357	14357	A	C	MI.23531	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	317	106	V	G	gTg/gGg	-5,79	0	0	benign	0,21	neutral	0,33	neutral	2,45	deleterious	-4,92	deleterious	-3,65	low_impact	1,34	neutral	0,84	neutral	0,89	deleterious	0,24	5,11	0,33	0,5	neutral	0,42	neutral	0,3	disease	0,56	neutral	0,47	1	neutral	0,6	deleterious	0,56	neutral	-6	neutral	0,28	medium_impact	-0,27	medium_impact	0,04	medium_impact	-0,02	0,78	0,85	42,48	7,64	N	0,42	N	0,8	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14357	14357	A	T	MI.23532	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	317	106	V	E	gTg/gAg	-5,79	0	0	benign	0,4	neutral	0,28	neutral	2,27	deleterious	-5,41	deleterious	-3,47	medium_impact	2	neutral	0,82	neutral	0,69	neutral	1,35	12,52	0,22	0,45	neutral	0,43	disease	0,7	disease	0,71	disease	0,63	3	neutral	0,67	neutral	0,44	neutral	-3	neutral	0,43	medium_impact	-0,64	medium_impact	-0,02	medium_impact	0,54	0,76	0,85	42,48	7,64	N	0,32	N	0,82	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14357	14357	A	G	MI.23533	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	317	106	V	A	gTg/gCg	-5,79	0	0	benign	0,01	neutral	0,51	neutral	2,33	deleterious	-3,33	neutral	-1,9	low_impact	0,92	neutral	0,95	neutral	0,95	deleterious	0,18	4,51	0,43	0,55	neutral	0,17	neutral	0,41	disease	0,56	neutral	0,46	1	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	0,22	medium_impact	-0,37	0,84	0,9	42,48	7,64	N	0,3	N	0,44	NA	NA	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14358	14358	C	G	MI.23534	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	316	106	V	L	Gtg/Ctg	-0,06	0	0	benign	0	neutral	0,65	neutral	2,41	neutral	-2,77	neutral	0,15	neutral_impact	-0,12	neutral	0,94	neutral	0,91	neutral	-0,39	0,4	0,39	0,5	neutral	0,12	neutral	0,29	neutral	0,29	neutral	0,43	1	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,11	medium_impact	1,95	medium_impact	0,36	low_impact	-1,24	0,87	0,9	42,48	7,64	N	0,33	N	0,38	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14358	14358	C	T	MI.23535	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	316	106	V	M	Gtg/Atg	-0,06	0	0	benign	0,03	neutral	0,22	neutral	2,25	deleterious	-4,51	neutral	0,48	neutral_impact	0,55	neutral	0,87	neutral	0,95	deleterious	0,28	5,53	0,49	0,55	neutral	0,2	neutral	0,2	neutral	0,38	neutral	0,36	3	neutral	0,77	deleterious	0,6	neutral	-6	neutral	0,12	medium_impact	0,59	medium_impact	-0,1	medium_impact	-0,68	0,84	0,9	42,48	7,64	N	0,48	N	0,55	NA	NA	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14358	14358	C	A	MI.23536	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	316	106	V	L	Gtg/Ttg	-0,06	0	0	benign	0	neutral	0,65	neutral	2,41	neutral	-2,77	neutral	0,15	neutral_impact	-0,12	neutral	0,94	neutral	0,91	neutral	-0,1	1,76	0,39	0,5	neutral	0,12	neutral	0,29	neutral	0,29	neutral	0,43	1	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,11	medium_impact	1,95	medium_impact	0,36	low_impact	-1,24	0,87	0,9	42,48	7,64	N	0,39	N	0,38	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14359	14359	C	A	MI.23537	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	315	105	W	C	tgG/tgT	-2,81	0	0	probably_damaging	0,96	neutral	0,2	neutral	2,33	deleterious	-4,42	deleterious	-5,93	medium_impact	2,02	neutral	0,87	neutral	0,83	deleterious	3,5	23,1	0,42	0,55	disease	0,66	disease	0,81	disease	0,62	disease	0,63	3	neutral	0,97	neutral	0,12	deleterious	1	deleterious	0,8	low_impact	-2,06	medium_impact	-0,13	medium_impact	0,55	0,43	0,8	49,12	8,67	N	0,36	N	0,78	NA	NA	0,65	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14359	14359	C	G	MI.23538	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	315	105	W	C	tgG/tgC	-2,81	0	0	probably_damaging	0,96	neutral	0,2	neutral	2,33	deleterious	-4,42	deleterious	-5,93	medium_impact	2,02	neutral	0,87	neutral	0,83	deleterious	3,06	22,4	0,42	0,55	disease	0,66	disease	0,81	disease	0,62	disease	0,63	3	neutral	0,97	neutral	0,12	deleterious	1	deleterious	0,8	low_impact	-2,06	medium_impact	-0,13	medium_impact	0,55	0,43	0,8	49,12	8,67	N	0,37	N	0,78	NA	NA	0,65	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14360	14360	C	A	MI.23539	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	314	105	W	L	tGg/tTg	-2,35	0	0	benign	0,02	neutral	0,95	neutral	2,69	neutral	-0,81	deleterious	-5,14	neutral_impact	0,27	neutral	0,94	neutral	0,89	deleterious	2,63	20,4	0,35	0,5	neutral	0,13	disease	0,64	neutral	0,49	neutral	0,46	1	neutral	0,01	deleterious	0,97	neutral	-6	neutral	0,16	medium_impact	0,75	medium_impact	0,92	medium_impact	-0,91	0,35	0,8	49,12	8,67	N	0,29	N	0,48	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6124	6124	T	C	MI.2354	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	221	74	M	T	aTa/aCa	6,83	1	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-0,36	deleterious	-3,5	medium_impact	3,13	neutral	0,63	damaging	0,14	deleterious	2,89	21,8	0,37	0,55	neutral	0,4	disease	0,92	disease	0,52	disease	0,67	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	medium_impact	1,79	0,54	0,9	5,65	8,41	N	0,42	N	0,79	disease_causing	0,94	0,11	.	.	.	.	.	prostate tumor	.	.	.	.	.	.	.	.	.
chrM	14360	14360	C	G	MI.23540	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	314	105	W	S	tGg/tCg	-2,35	0	0	possibly_damaging	0,82	neutral	0,53	neutral	2,4	neutral	-2,94	deleterious	-6,64	low_impact	1,79	neutral	0,86	neutral	0,87	deleterious	3,02	22,3	0,3	0,45	neutral	0,44	disease	0,81	disease	0,66	disease	0,6	2	neutral	0,8	neutral	0,36	neutral	-3	deleterious	0,72	low_impact	-1,4	medium_impact	0,24	medium_impact	0,36	0,42	0,8	49,12	8,67	N	0,23	N	0,8	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14361	14361	A	C	MI.23541	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	313	105	W	G	Tgg/Ggg	-0,52	0	0	possibly_damaging	0,73	neutral	0,42	neutral	2,34	deleterious	-3,89	deleterious	-6,69	low_impact	1,55	neutral	0,81	neutral	0,81	deleterious	2,52	19,6	0,32	0,5	disease	0,58	disease	0,74	disease	0,69	disease	0,61	2	neutral	0,73	neutral	0,35	neutral	-3	deleterious	0,69	low_impact	-1,19	medium_impact	0,13	medium_impact	0,16	0,54	0,8	49,12	8,67	N	0,27	N	0,69	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14361	14361	A	G	MI.23542	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	313	105	W	R	Tgg/Cgg	-0,52	0	0	probably_damaging	0,91	neutral	0,33	neutral	2,32	deleterious	-3,52	deleterious	-6,87	medium_impact	2,83	neutral	0,78	neutral	0,49	deleterious	2,68	20,7	0,45	0,55	disease	0,55	disease	0,83	disease	0,73	disease	0,79	6	neutral	0,92	neutral	0,21	deleterious	1	deleterious	0,78	low_impact	-1,72	medium_impact	0,04	medium_impact	1,23	0,45	0,8	49,12	8,67	N	0,29	N	0,84	NA	NA	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14363	14363	A	T	MI.23543	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	311	104	L	Q	cTg/cAg	-6,48	0	0	probably_damaging	0,91	neutral	0,28	neutral	2	deleterious	-3,2	deleterious	-3,23	medium_impact	2,83	neutral	0,78	neutral	0,49	deleterious	3,55	23,1	0,21	0,45	neutral	0,49	disease	0,69	neutral	0,5	disease	0,53	1	neutral	0,93	neutral	0,19	deleterious	1	deleterious	0,72	low_impact	-1,72	medium_impact	-0,02	medium_impact	1,23	0,81	0,85	48,23	8,5	N	0,33	N	0,62	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14363	14363	A	G	MI.23544	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	311	104	L	P	cTg/cCg	-6,48	0	0	probably_damaging	0,91	neutral	0,21	neutral	2,02	deleterious	-4	deleterious	-4,17	medium_impact	2,48	neutral	0,73	neutral	0,4	deleterious	3,79	23,4	0,16	0,45	disease	0,56	disease	0,89	disease	0,51	disease	0,75	5	neutral	0,94	neutral	0,15	deleterious	1	deleterious	0,8	low_impact	-1,72	medium_impact	-0,11	medium_impact	0,94	0,72	0,85	48,23	8,5	N	0,32	N	0,84	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14363	14363	A	C	MI.23545	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	311	104	L	R	cTg/cGg	-6,48	0	0	probably_damaging	0,91	neutral	0,34	neutral	2,01	neutral	-1,74	deleterious	-3,68	medium_impact	2,48	neutral	0,73	neutral	0,43	deleterious	2,62	20,3	0,18	0,45	neutral	0,47	disease	0,85	disease	0,62	disease	0,78	6	neutral	0,92	neutral	0,22	deleterious	1	deleterious	0,78	low_impact	-1,72	medium_impact	0,05	medium_impact	0,94	0,83	0,9	48,23	8,5	N	0,33	N	0,63	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14364	14364	G	C	MI.23546	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	310	104	L	V	Ctg/Gtg	-0,52	0	0,1	benign	0,05	neutral	0,58	neutral	2,09	neutral	-1,35	neutral	-0,56	neutral_impact	0,69	neutral	0,9	neutral	0,98	neutral	1,11	11,28	0,43	0,55	neutral	0,13	neutral	0,34	neutral	0,27	neutral	0,45	1	neutral	0,36	deleterious	0,77	neutral	-6	neutral	0,15	medium_impact	0,38	medium_impact	0,28	medium_impact	-0,56	0,85	0,9	48,23	8,5	N	0,39	N	0,32	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14364	14364	G	T	MI.23547	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	310	104	L	M	Ctg/Atg	-0,52	0	0,1	benign	0,26	neutral	0,26	neutral	2,03	neutral	-2,73	neutral	-0,16	low_impact	1,03	neutral	0,86	neutral	0,99	deleterious	1,86	15,36	0,33	0,5	neutral	0,33	neutral	0,28	neutral	0,32	neutral	0,45	1	neutral	0,69	deleterious	0,5	neutral	-6	neutral	0,24	medium_impact	-0,38	medium_impact	-0,05	medium_impact	-0,28	0,68	0,85	48,23	8,5	N	0,49	N	0,41	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14366	14366	A	C	MI.23548	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	308	103	V	G	gTg/gGg	-2,81	0	0	probably_damaging	0,96	neutral	0,36	neutral	2,25	deleterious	-3,02	deleterious	-5,76	low_impact	1,64	neutral	0,85	neutral	0,75	deleterious	3,53	23,1	0,31	0,45	neutral	0,33	disease	0,68	neutral	0,48	neutral	0,49	0	neutral	0,96	neutral	0,2	neutral	-2	deleterious	0,7	low_impact	-2,06	medium_impact	0,07	medium_impact	0,23	0,84	0,9	22,12	23,58	N	0,29	N	0,75	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14366	14366	A	T	MI.23549	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	308	103	V	E	gTg/gAg	-2,81	0	0	probably_damaging	0,97	neutral	0,3	neutral	2,18	deleterious	-3,09	deleterious	-5,02	medium_impact	2,98	neutral	0,81	neutral	0,74	deleterious	4,36	24,1	0,23	0,45	disease	0,52	disease	0,84	disease	0,66	disease	0,64	3	neutral	0,98	neutral	0,17	deleterious	1	deleterious	0,81	low_impact	-2,18	medium_impact	0	medium_impact	1,36	0,9	0,95	22,12	23,58	N	0,3	N	0,83	NA	NA	0,66	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6125	6125	A	T	MI.2355	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	222	74	M	I	atA/atT	7,53	1	0,01	probably_damaging	0,96	deleterious	0	neutral	2,87	neutral	0,66	neutral	-2,05	medium_impact	3,34	damaging	0,59	damaging	0,14	deleterious	3,39	23	0,47	0,55	neutral	0,24	disease	0,95	disease	0,57	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,77	low_impact	-2,06	low_impact	-1,48	medium_impact	1,99	0,67	0,9	5,65	8,41	P	0,49	N	0,87	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14366	14366	A	G	MI.23550	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	308	103	V	A	gTg/gCg	-2,81	0	0	possibly_damaging	0,69	neutral	0,52	neutral	2,35	neutral	-1,83	deleterious	-3,05	low_impact	1,63	neutral	0,92	neutral	0,98	deleterious	2,34	18,43	0,41	0,5	neutral	0,23	disease	0,57	neutral	0,43	neutral	0,45	1	neutral	0,66	neutral	0,42	neutral	-3	deleterious	0,58	low_impact	-1,11	medium_impact	0,23	medium_impact	0,23	0,86	0,9	22,12	23,58	N	0,33	N	0,21	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14367	14367	C	T	MI.23551	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	307	103	V	M	Gtg/Atg	-0,29	0	0	probably_damaging	0,92	neutral	0,23	neutral	2,38	neutral	-2,71	neutral	-1,71	low_impact	1,78	neutral	0,9	neutral	0,96	deleterious	2,62	20,3	0,49	0,55	neutral	0,38	neutral	0,43	neutral	0,4	neutral	0,45	1	neutral	0,94	neutral	0,16	neutral	-2	deleterious	0,67	low_impact	-1,77	medium_impact	-0,09	medium_impact	0,35	0,87	0,9	22,12	23,58	N	0,49	N	0,54	NA	NA	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14367	14367	C	G	MI.23552	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	307	103	V	L	Gtg/Ctg	-0,29	0	0	benign	0,06	neutral	0,67	neutral	2,34	neutral	-0,88	neutral	-1,54	low_impact	1,28	neutral	0,85	neutral	0,94	deleterious	0,89	9,99	0,44	0,55	neutral	0,16	neutral	0,46	neutral	0,45	neutral	0,45	1	neutral	0,25	deleterious	0,81	neutral	-6	neutral	0,16	medium_impact	0,3	medium_impact	0,38	medium_impact	-0,07	0,89	0,9	22,12	23,58	N	0,29	N	0,35	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14367	14367	C	A	MI.23553	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	307	103	V	L	Gtg/Ttg	-0,29	0	0	benign	0,06	neutral	0,67	neutral	2,34	neutral	-0,88	neutral	-1,54	low_impact	1,28	neutral	0,85	neutral	0,94	neutral	1,23	11,92	0,44	0,55	neutral	0,16	neutral	0,46	neutral	0,45	neutral	0,45	1	neutral	0,25	deleterious	0,81	neutral	-6	neutral	0,16	medium_impact	0,3	medium_impact	0,38	medium_impact	-0,07	0,89	0,9	22,12	23,58	N	0,29	N	0,35	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14368	14368	C	A	MI.23554	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	306	102	L	F	ttG/ttT	-2,35	0	0	possibly_damaging	0,89	neutral	0,76	neutral	2,57	neutral	-1,78	neutral	-2,49	low_impact	1,47	neutral	0,85	neutral	0,97	deleterious	2,82	21,5	0,47	0,55	neutral	0,33	neutral	0,33	neutral	0,3	neutral	0,46	1	neutral	0,87	neutral	0,44	neutral	-3	deleterious	0,65	low_impact	-1,63	medium_impact	0,48	medium_impact	0,09	0,77	0,85	18,14	17,58	N	0,26	N	0,34	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14368	14368	C	G	MI.23555	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	306	102	L	F	ttG/ttC	-2,35	0	0	possibly_damaging	0,89	neutral	0,76	neutral	2,57	neutral	-1,78	neutral	-2,49	low_impact	1,47	neutral	0,85	neutral	0,97	deleterious	2,34	18,45	0,47	0,55	neutral	0,33	neutral	0,33	neutral	0,3	neutral	0,46	1	neutral	0,87	neutral	0,44	neutral	-3	deleterious	0,65	low_impact	-1,63	medium_impact	0,48	medium_impact	0,09	0,77	0,85	18,14	17,58	N	0,26	N	0,34	NA	NA	0,52	rs2853816	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14369	14369	A	C	MI.23556	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	305	102	L	W	tTg/tGg	-9,92	0	0	probably_damaging	0,98	neutral	0,19	neutral	2,11	deleterious	-3,67	deleterious	-4,27	medium_impact	2,19	neutral	0,91	neutral	0,94	deleterious	2,31	18,2	0,2	0,45	disease	0,66	disease	0,58	neutral	0,38	disease	0,52	0	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,75	low_impact	-2,35	medium_impact	-0,14	medium_impact	0,7	0,72	0,85	18,14	17,58	N	0,45	N	0,47	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14369	14369	A	G	MI.23557	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	305	102	L	S	tTg/tCg	-9,92	0	0	possibly_damaging	0,87	neutral	0,43	neutral	2,15	neutral	-1,86	deleterious	-3,67	medium_impact	1,99	neutral	0,83	neutral	0,86	deleterious	3,77	23,4	0,29	0,45	neutral	0,29	neutral	0,5	neutral	0,49	neutral	0,46	1	neutral	0,87	neutral	0,28	NA	0	deleterious	0,67	low_impact	-1,55	medium_impact	0,14	medium_impact	0,53	0,84	0,9	18,14	17,58	N	0,33	N	0,58	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14370	14370	A	C	MI.23558	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	304	102	L	V	Ttg/Gtg	0,63	0	0	benign	0,1	neutral	0,55	neutral	2,24	neutral	-2,13	neutral	-0,87	neutral_impact	0,25	neutral	0,94	neutral	0,99	neutral	-0,78	0,05	0,44	0,55	neutral	0,13	neutral	0,17	neutral	0,27	neutral	0,26	5	neutral	0,37	deleterious	0,73	neutral	-6	neutral	0,16	medium_impact	0,08	medium_impact	0,26	medium_impact	-0,93	0,84	0,9	18,14	17,58	N	0,41	N	0,25	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14370	14370	A	T	MI.23559	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	304	102	L	M	Ttg/Atg	0,63	0	0	benign	0,24	neutral	0,25	neutral	2,16	neutral	-2,59	neutral	-0,46	neutral_impact	0,72	neutral	0,94	neutral	0,97	neutral	1,07	11,06	0,33	0,5	neutral	0,22	neutral	0,18	neutral	0,33	neutral	0,3	4	neutral	0,7	deleterious	0,51	neutral	-6	neutral	0,3	medium_impact	-0,34	medium_impact	-0,06	medium_impact	-0,54	0,77	0,85	18,14	17,58	P	0,56	P	0,17	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6125	6125	A	C	MI.2356	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	222	74	M	I	atA/atC	7,53	1	0,01	probably_damaging	0,96	deleterious	0	neutral	2,87	neutral	0,66	neutral	-2,05	medium_impact	3,34	damaging	0,59	damaging	0,14	deleterious	3,34	22,9	0,47	0,55	neutral	0,24	disease	0,95	disease	0,57	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,77	low_impact	-2,06	low_impact	-1,48	medium_impact	1,99	0,67	0,9	5,65	8,41	P	0,49	N	0,87	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14372	14372	C	T	MI.23560	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	302	101	G	E	gGa/gAa	-9	0	0	benign	0	neutral	0,3	neutral	2,27	neutral	-0,47	neutral	-0,52	low_impact	1,65	neutral	0,72	neutral	0,45	deleterious	2,69	20,7	0,3	0,45	neutral	0,3	disease	0,83	disease	0,66	disease	0,76	5	neutral	0,7	deleterious	0,65	neutral	-6	neutral	0,24	medium_impact	1,95	medium_impact	0	medium_impact	0,24	0,75	0,85	49,56	8,63	N	0,31	N	0,67	NA	NA	0,2	rs386829210	Uncertain significance|Uncertain significance	Acute_megakaryoblastic_leukemia|Mediastinal_germ_cell_tumor	RCV000202587.1|RCV000202587.1	MedGen|MedGen	.	.	.	.	.	.	.	.	.	.
chrM	14372	14372	C	A	MI.23561	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	302	101	G	V	gGa/gTa	-9	0	0	benign	0	neutral	0,54	neutral	2,4	neutral	-1,97	neutral	2,72	neutral_impact	-0,77	neutral	0,93	neutral	0,93	deleterious	0,22	4,84	0,22	0,45	neutral	0,09	disease	0,65	neutral	0,32	neutral	0,43	1	neutral	0,46	deleterious	0,77	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,25	low_impact	-1,79	0,71	0,85	49,56	8,63	N	0,22	N	0,31	NA	NA	0,16	rs386829210	Uncertain significance|Uncertain significance	Acute_megakaryoblastic_leukemia|Mediastinal_germ_cell_tumor	RCV000202587.1|RCV000202587.1	MedGen|MedGen	.	.	.	.	.	.	.	.	.	.
chrM	14372	14372	C	G	MI.23562	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	302	101	G	A	gGa/gCa	-9	0	0	benign	0	neutral	0,54	neutral	2,34	neutral	-0,87	neutral	1,21	neutral_impact	0,2	neutral	0,85	neutral	0,93	deleterious	0,05	3,07	0,46	0,55	neutral	0,12	disease	0,57	neutral	0,44	neutral	0,45	1	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,15	medium_impact	1,95	medium_impact	0,25	medium_impact	-0,97	0,77	0,85	49,56	8,63	N	0,31	N	0,33	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14373	14373	C	A	MI.23563	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	301	101	G	W	Gga/Tga	-0,52	0	0	possibly_damaging	0,7	neutral	0,19	neutral	2,26	deleterious	-4,73	neutral	0,26	low_impact	1,3	neutral	0,83	neutral	0,52	deleterious	3,54	23,1	0,21	0,45	disease	0,53	disease	0,87	disease	0,53	disease	0,76	5	neutral	0,85	neutral	0,25	neutral	-3	deleterious	0,65	low_impact	-1,13	medium_impact	-0,14	medium_impact	-0,05	0,55	0,8	49,56	8,63	N	0,4	N	0,56	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14373	14373	C	G	MI.23564	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	301	101	G	R	Gga/Cga	-0,52	0	0	benign	0,18	neutral	0,35	neutral	2,27	neutral	-1,21	neutral	-0,3	low_impact	1,65	neutral	0,77	neutral	0,38	deleterious	2,72	20,9	0,21	0,45	neutral	0,3	disease	0,82	disease	0,68	disease	0,76	5	neutral	0,58	deleterious	0,59	neutral	-6	neutral	0,41	medium_impact	-0,19	medium_impact	0,06	medium_impact	0,24	0,81	0,85	49,56	8,63	N	0,28	N	0,58	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14375	14375	A	T	MI.23565	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	299	100	V	E	gTa/gAa	-12,67	0	0	possibly_damaging	0,5	neutral	0,35	neutral	2,13	deleterious	-4,15	deleterious	-3,58	medium_impact	2,6	neutral	0,84	neutral	0,47	deleterious	4,44	24,2	0,19	0,45	disease	0,72	disease	0,84	disease	0,71	disease	0,8	6	neutral	0,63	neutral	0,43	NA	0	deleterious	0,54	medium_impact	-0,8	medium_impact	0,06	medium_impact	1,04	0,54	0,8	27,43	8,87	N	0,29	N	0,88	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14375	14375	A	G	MI.23566	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	299	100	V	A	gTa/gCa	-12,67	0	0	benign	0,01	neutral	0,47	neutral	2,25	neutral	-2,23	neutral	-1,85	low_impact	1,7	neutral	0,94	neutral	0,85	neutral	1,05	10,92	0,3	0,45	neutral	0,42	neutral	0,47	disease	0,53	neutral	0,49	0	neutral	0,52	deleterious	0,73	neutral	-6	neutral	0,18	medium_impact	1,03	medium_impact	0,18	medium_impact	0,28	0,54	0,8	27,43	8,87	N	0,44	N	0,46	NA	NA	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14375	14375	A	C	MI.23567	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	299	100	V	G	gTa/gGa	-12,67	0	0	benign	0,3	neutral	0,4	neutral	2,2	deleterious	-4,38	deleterious	-3,77	low_impact	1,24	neutral	0,88	neutral	0,84	neutral	0,89	10,04	0,26	0,45	disease	0,71	disease	0,62	disease	0,55	disease	0,53	1	neutral	0,52	deleterious	0,55	neutral	-6	neutral	0,38	medium_impact	-0,46	medium_impact	0,11	medium_impact	-0,1	0,56	0,8	27,43	8,87	N	0,41	N	0,84	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14376	14376	C	G	MI.23568	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	298	100	V	L	Gta/Cta	-0,06	0	0	benign	0,01	neutral	1	neutral	2,41	neutral	-0,72	neutral	0,63	neutral_impact	0,46	neutral	0,86	neutral	0,91	neutral	-0,78	0,05	0,43	0,55	neutral	0,14	neutral	0,34	neutral	0,29	neutral	0,44	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,12	medium_impact	1,03	high_impact	1,87	medium_impact	-0,76	0,76	0,85	27,43	8,87	N	0,28	N	0,32	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14376	14376	C	A	MI.23569	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	298	100	V	L	Gta/Tta	-0,06	0	0	benign	0,01	neutral	1	neutral	2,41	neutral	-0,72	neutral	0,63	neutral_impact	0,46	neutral	0,86	neutral	0,91	neutral	-0,45	0,29	0,43	0,55	neutral	0,14	neutral	0,34	neutral	0,29	neutral	0,44	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,12	medium_impact	1,03	high_impact	1,87	medium_impact	-0,76	0,76	0,85	27,43	8,87	N	0,28	N	0,32	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6126	6126	A	G	MI.2357	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	223	75	I	V	Atc/Gtc	-1,26	0	0	probably_damaging	0,92	deleterious	0	neutral	2,87	neutral	-0,63	neutral	-0,61	medium_impact	2,26	damaging	0,51	neutral	0,43	deleterious	2,97	22,1	0,62	0,65	neutral	0,28	neutral	0,47	neutral	0,36	neutral	0,41	2	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,63	low_impact	-1,76	low_impact	-1,48	medium_impact	0,99	0,5	0,9	10,92	16,76	N	0,5	N	0,23	disease_causing	0,93	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14376	14376	C	T	MI.23570	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	298	100	V	M	Gta/Ata	-0,06	0	0	benign	0,09	neutral	0,28	neutral	2,18	neutral	-2,63	neutral	0,03	low_impact	1,21	neutral	0,93	neutral	0,87	deleterious	0,71	8,89	0,39	0,5	neutral	0,43	neutral	0,36	neutral	0,42	neutral	0,46	1	neutral	0,69	deleterious	0,6	neutral	-6	neutral	0,2	medium_impact	0,13	medium_impact	-0,02	medium_impact	-0,13	0,8	0,85	27,43	8,87	N	0,54	P	0,56	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14377	14377	C	A	MI.23571	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	297	99	E	D	gaG/gaT	-3,27	0	0	probably_damaging	1	neutral	0,19	neutral	2,3	neutral	1,11	deleterious	-2,95	medium_impact	3,49	neutral	0,82	damaging	0,23	deleterious	4,24	23,9	0,33	0,5	neutral	0,29	neutral	0,4	disease	0,58	neutral	0,48	0	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,68	low_impact	-3,55	medium_impact	-0,14	medium_impact	1,78	0,81	0,85	43,36	8,06	N	0,31	N	0,83	NA	NA	0,53	rs56407536	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14377	14377	C	G	MI.23572	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	297	99	E	D	gaG/gaC	-3,27	0	0	probably_damaging	1	neutral	0,19	neutral	2,3	neutral	1,11	deleterious	-2,95	medium_impact	3,49	neutral	0,82	damaging	0,23	deleterious	3,84	23,4	0,33	0,5	neutral	0,29	neutral	0,4	disease	0,58	neutral	0,48	0	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,68	low_impact	-3,55	medium_impact	-0,14	medium_impact	1,78	0,81	0,85	43,36	8,06	N	0,4	N	0,83	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14378	14378	T	A	MI.23573	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	296	99	E	V	gAg/gTg	-3,5	0	0	probably_damaging	1	neutral	0,91	neutral	2,49	neutral	2,68	deleterious	-6,66	medium_impact	2,29	neutral	0,81	neutral	0,31	deleterious	4,58	24,4	0,21	0,45	neutral	0,27	neutral	0,35	neutral	0,38	neutral	0,45	1	deleterious	1	neutral	0,46	deleterious	1	deleterious	0,68	low_impact	-3,55	medium_impact	0,76	medium_impact	0,78	0,7	0,85	43,36	8,06	N	0,27	N	0,72	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14378	14378	T	G	MI.23574	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	296	99	E	A	gAg/gCg	-3,5	0	0	probably_damaging	1	neutral	0,55	neutral	2,41	neutral	3,25	deleterious	-5,84	medium_impact	2,68	neutral	0,78	neutral	0,43	deleterious	4,05	23,7	0,22	0,45	neutral	0,22	neutral	0,38	disease	0,57	neutral	0,47	1	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,68	low_impact	-3,55	medium_impact	0,26	medium_impact	1,11	0,7	0,85	43,36	8,06	N	0,32	N	0,64	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14378	14378	T	C	MI.23575	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	296	99	E	G	gAg/gGg	-3,5	0	0	probably_damaging	1	neutral	0,38	neutral	2,33	neutral	3,54	deleterious	-6,78	medium_impact	2,52	neutral	0,8	neutral	0,35	deleterious	4,16	23,8	0,29	0,45	neutral	0,25	neutral	0,25	disease	0,61	neutral	0,46	1	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,67	low_impact	-3,55	medium_impact	0,09	medium_impact	0,97	0,7	0,85	43,36	8,06	N	0,36	N	0,29	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14379	14379	C	G	MI.23576	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	295	99	E	Q	Gag/Cag	-0,75	0	0	probably_damaging	1	neutral	0,26	neutral	2,31	neutral	0,03	deleterious	-2,96	medium_impact	2,94	neutral	0,88	neutral	0,28	deleterious	3,62	23,2	0,39	0,5	neutral	0,27	neutral	0,29	disease	0,55	neutral	0,47	1	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,68	low_impact	-3,55	medium_impact	-0,05	medium_impact	1,32	0,81	0,85	43,36	8,06	N	0,41	N	0,87	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14379	14379	C	T	MI.23577	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	295	99	E	K	Gag/Aag	-0,75	0	0	probably_damaging	1	neutral	0,26	neutral	2,31	neutral	0,27	deleterious	-3,94	medium_impact	3,15	neutral	0,78	damaging	0,17	deleterious	4,8	24,8	0,29	0,45	neutral	0,21	disease	0,58	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,7	low_impact	-3,55	medium_impact	-0,05	medium_impact	1,5	0,9	0,95	43,36	8,06	N	0,34	N	0,93	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14380	14380	C	G	MI.23578	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	294	98	M	I	atG/atC	0,4	0	0	probably_damaging	0,99	neutral	0,55	neutral	2,53	neutral	-0,32	neutral	-2,2	medium_impact	2	neutral	0,9	neutral	0,91	deleterious	2,66	20,6	0,57	0,65	neutral	0,17	disease	0,5	neutral	0,42	neutral	0,43	1	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,66	low_impact	-2,63	medium_impact	0,26	medium_impact	0,54	0,73	0,85	48,67	8,57	N	0,3	N	0,89	NA	NA	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14380	14380	C	A	MI.23579	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	294	98	M	I	atG/atT	0,4	0	0	probably_damaging	0,99	neutral	0,55	neutral	2,53	neutral	-0,32	neutral	-2,2	medium_impact	2	neutral	0,9	neutral	0,91	deleterious	3,02	22,3	0,57	0,65	neutral	0,17	disease	0,5	neutral	0,42	neutral	0,43	1	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,66	low_impact	-2,63	medium_impact	0,26	medium_impact	0,54	0,73	0,85	48,67	8,57	N	0,31	N	0,89	NA	NA	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6126	6126	A	C	MI.2358	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	223	75	I	L	Atc/Ctc	-1,26	0	0	probably_damaging	0,97	deleterious	0	neutral	2,91	neutral	-0,56	neutral	-1,17	medium_impact	3,25	damaging	0,54	neutral	0,69	deleterious	3,69	23,3	0,39	0,55	neutral	0,26	disease	0,62	neutral	0,37	neutral	0,44	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,65	low_impact	-2,18	low_impact	-1,48	medium_impact	1,9	0,77	0,9	10,92	16,76	N	0,51	P	0,61	disease_causing	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14381	14381	A	G	MI.23580	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	293	98	M	T	aTg/aCg	-9,46	0	0	probably_damaging	0,99	neutral	0,25	neutral	2,3	neutral	-1,29	deleterious	-4,14	medium_impact	2,75	neutral	0,86	neutral	0,76	deleterious	2,03	16,38	0,38	0,5	neutral	0,26	neutral	0,48	disease	0,58	disease	0,56	1	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,68	low_impact	-2,63	medium_impact	-0,06	medium_impact	1,16	0,55	0,8	48,67	8,57	N	0,4	N	0,87	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14381	14381	A	T	MI.23581	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	293	98	M	K	aTg/aAg	-9,46	0	0	probably_damaging	0,99	neutral	0,25	neutral	2,24	deleterious	-3,75	deleterious	-4,69	medium_impact	3,1	neutral	0,78	neutral	0,5	deleterious	3,73	23,3	0,26	0,45	neutral	0,39	disease	0,76	disease	0,67	disease	0,76	5	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,74	low_impact	-2,63	medium_impact	-0,06	medium_impact	1,46	0,63	0,8	48,67	8,57	N	0,35	N	0,96	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14382	14382	T	A	MI.23582	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	292	98	M	L	Atg/Ttg	0,86	0	0	probably_damaging	0,98	neutral	0,78	neutral	2,5	neutral	-0,3	neutral	-1,82	low_impact	0,86	neutral	0,9	neutral	0,98	deleterious	2,43	19,02	0,43	0,55	neutral	0,11	neutral	0,31	neutral	0,37	neutral	0,44	1	neutral	0,97	neutral	0,4	neutral	-2	deleterious	0,63	low_impact	-2,35	medium_impact	0,51	medium_impact	-0,42	0,63	0,8	48,67	8,57	N	0,36	N	0,74	NA	NA	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14382	14382	T	G	MI.23583	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	292	98	M	L	Atg/Ctg	0,86	0	0	probably_damaging	0,98	neutral	0,78	neutral	2,5	neutral	-0,3	neutral	-1,82	low_impact	0,86	neutral	0,9	neutral	0,98	deleterious	2,3	18,17	0,43	0,55	neutral	0,11	neutral	0,31	neutral	0,37	neutral	0,44	1	neutral	0,97	neutral	0,4	neutral	-2	deleterious	0,63	low_impact	-2,35	medium_impact	0,51	medium_impact	-0,42	0,63	0,8	48,67	8,57	N	0,36	N	0,74	NA	NA	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14382	14382	T	C	MI.23584	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	292	98	M	V	Atg/Gtg	0,86	0	0	probably_damaging	0,99	neutral	1	neutral	2,36	neutral	-0,51	neutral	-2,05	low_impact	1,16	neutral	0,92	neutral	0,97	neutral	1,02	10,77	0,55	0,6	neutral	0,13	neutral	0,28	neutral	0,43	neutral	0,43	1	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,64	low_impact	-2,63	high_impact	1,87	medium_impact	-0,17	0,62	0,8	48,67	8,57	N	0,34	N	0,85	NA	NA	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14384	14384	G	T	MI.23585	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	290	97	A	E	gCg/gAg	-9,46	0	0	possibly_damaging	0,46	neutral	0,26	neutral	2,16	neutral	-2,54	neutral	-1,88	low_impact	1,83	neutral	0,76	neutral	0,6	deleterious	2,15	17,16	0,15	0,4	neutral	0,3	neutral	0,37	disease	0,66	neutral	0,48	0	neutral	0,71	neutral	0,4	neutral	-3	neutral	0,42	medium_impact	-0,73	medium_impact	-0,05	medium_impact	0,39	0,82	0,85	48,23	8,28	N	0,46	N	0,42	NA	NA	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14384	14384	G	C	MI.23586	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	290	97	A	G	gCg/gGg	-9,46	0	0	benign	0,33	neutral	0,55	neutral	2,21	neutral	-0,59	neutral	-2,42	neutral_impact	0,13	neutral	0,84	neutral	0,72	deleterious	0,73	9	0,19	0,45	neutral	0,18	neutral	0,08	neutral	0,32	neutral	0,3	4	neutral	0,36	deleterious	0,61	neutral	-6	neutral	0,35	medium_impact	-0,51	medium_impact	0,26	low_impact	-1,03	0,72	0,85	48,23	8,28	N	0,4	N	0,35	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14384	14384	G	A	MI.23587	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	290	97	A	V	gCg/gTg	-9,46	0	0	benign	0	neutral	0,68	neutral	2,29	neutral	0,89	neutral	2,11	neutral_impact	-0,62	neutral	0,96	neutral	0,98	deleterious	0,06	3,23	0,32	0,5	neutral	0,09	neutral	0,06	neutral	0,33	neutral	0,24	5	neutral	0,31	deleterious	0,84	neutral	-6	neutral	0,07	medium_impact	1,95	medium_impact	0,39	low_impact	-1,66	0,79	0,85	48,23	8,28	N	0,38	N	0,04	NA	NA	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14385	14385	C	G	MI.23588	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	289	97	A	P	Gcg/Ccg	2,23	0	0	possibly_damaging	0,65	neutral	0,19	neutral	2,19	neutral	-2,23	neutral	-2,04	low_impact	1,83	neutral	0,73	neutral	0,5	deleterious	3,71	23,3	0,15	0,4	neutral	0,39	neutral	0,47	disease	0,54	disease	0,54	1	neutral	0,83	neutral	0,27	neutral	-3	deleterious	0,59	low_impact	-1,04	medium_impact	-0,14	medium_impact	0,39	0,79	0,85	48,23	8,28	N	0,45	N	0,41	NA	NA	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14385	14385	C	A	MI.23589	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	289	97	A	S	Gcg/Tcg	2,23	0	0	benign	0,33	neutral	0,5	neutral	2,2	neutral	-0,83	neutral	-1,02	low_impact	0,94	neutral	0,73	neutral	0,79	deleterious	2,27	17,99	0,29	0,45	neutral	0,19	neutral	0,14	neutral	0,42	neutral	0,31	4	neutral	0,41	deleterious	0,59	neutral	-6	neutral	0,31	medium_impact	-0,51	medium_impact	0,21	medium_impact	-0,35	0,83	0,9	48,23	8,28	N	0,47	N	0,14	NA	NA	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6126	6126	A	T	MI.2359	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	223	75	I	F	Atc/Ttc	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,91	neutral	-1,23	neutral	-2,5	medium_impact	2,87	damaging	0,54	neutral	0,4	deleterious	3,66	23,2	0,33	0,55	neutral	0,28	disease	0,77	neutral	0,39	disease	0,54	1	deleterious	1	neutral	0	deleterious	5	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	medium_impact	1,55	0,76	0,9	10,92	16,76	N	0,38	N	0,85	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14385	14385	C	T	MI.23590	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	289	97	A	T	Gcg/Acg	2,23	0	0	benign	0,2	neutral	0,46	neutral	2,22	neutral	-0,23	neutral	-0,19	low_impact	1,49	neutral	0,86	neutral	0,77	neutral	1,48	13,22	0,3	0,45	neutral	0,17	neutral	0,08	neutral	0,45	neutral	0,31	4	neutral	0,45	deleterious	0,63	neutral	-6	neutral	0,23	medium_impact	-0,24	medium_impact	0,17	medium_impact	0,11	0,77	0,85	48,23	8,28	N	0,45	N	0,12	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14386	14386	T	A	MI.23591	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	288	96	L	F	ttA/ttT	-10,83	0	0,01	benign	0,09	neutral	0,91	neutral	2,28	neutral	-1,46	deleterious	-2,68	low_impact	1,51	neutral	0,89	neutral	0,86	deleterious	0,76	9,19	0,36	0,5	neutral	0,41	neutral	0,46	neutral	0,37	neutral	0,47	1	neutral	0,03	deleterious	0,91	neutral	-6	neutral	0,23	medium_impact	0,13	medium_impact	0,76	medium_impact	0,13	0,66	0,8	34,51	7,56	N	0,37	N	0,83	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14386	14386	T	G	MI.23592	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	288	96	L	F	ttA/ttC	-10,83	0	0,01	benign	0,09	neutral	0,91	neutral	2,28	neutral	-1,46	deleterious	-2,68	low_impact	1,51	neutral	0,89	neutral	0,86	deleterious	0,65	8,5	0,36	0,5	neutral	0,41	neutral	0,46	neutral	0,37	neutral	0,47	1	neutral	0,03	deleterious	0,91	neutral	-6	neutral	0,23	medium_impact	0,13	medium_impact	0,76	medium_impact	0,13	0,66	0,8	34,51	7,56	N	0,32	N	0,83	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14387	14387	A	G	MI.23593	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	287	96	L	S	tTa/tCa	-10,83	0	0	probably_damaging	0,91	neutral	0,52	neutral	2,3	neutral	-0,4	deleterious	-4,58	medium_impact	2,23	neutral	0,8	neutral	0,65	deleterious	3,8	23,4	0,26	0,45	disease	0,57	disease	0,67	disease	0,54	disease	0,7	4	neutral	0,9	neutral	0,31	deleterious	1	deleterious	0,74	low_impact	-1,72	medium_impact	0,23	medium_impact	0,73	0,66	0,8	34,51	7,56	N	0,25	N	0,91	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14387	14387	A	C	MI.23594	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	287	96	L	W	tTa/tGa	-10,83	0	0	probably_damaging	0,95	neutral	0,18	neutral	2,19	deleterious	-5,48	deleterious	-4,82	medium_impact	3,33	neutral	0,78	neutral	0,38	deleterious	3,37	22,9	0,15	0,4	disease	0,78	disease	0,73	disease	0,57	disease	0,73	5	neutral	0,97	neutral	0,12	deleterious	1	deleterious	0,78	low_impact	-1,97	medium_impact	-0,16	medium_impact	1,65	0,61	0,8	34,51	7,56	N	0,33	N	0,93	NA	NA	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14388	14388	A	T	MI.23595	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	286	96	L	M	Tta/Ata	2,92	0,02	0	benign	0,33	neutral	0,37	neutral	2,25	neutral	-2,26	neutral	-1,08	low_impact	1,66	neutral	0,86	neutral	0,88	deleterious	2,12	16,99	0,34	0,5	neutral	0,45	neutral	0,26	neutral	0,35	neutral	0,45	1	neutral	0,56	deleterious	0,52	neutral	-6	deleterious	0,47	medium_impact	-0,51	medium_impact	0,08	medium_impact	0,25	0,68	0,85	34,51	7,56	N	0,43	N	0,58	NA	NA	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14388	14388	A	C	MI.23596	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	286	96	L	V	Tta/Gta	2,92	0,02	0	benign	0,33	neutral	0,68	neutral	2,31	neutral	-1,05	neutral	-1,04	low_impact	1,18	neutral	0,87	neutral	0,98	neutral	1,05	10,97	0,31	0,5	neutral	0,25	neutral	0,15	neutral	0,3	neutral	0,27	5	neutral	0,26	deleterious	0,68	neutral	-6	deleterious	0,44	medium_impact	-0,51	medium_impact	0,39	medium_impact	-0,15	0,68	0,85	34,51	7,56	N	0,39	N	0,42	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14390	14390	C	A	MI.23597	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	284	95	G	V	gGg/gTg	-12,44	0	0	probably_damaging	1	neutral	0,57	neutral	2,41	neutral	1,35	deleterious	-8,4	low_impact	1,81	neutral	0,81	neutral	0,45	deleterious	4,31	24	0,28	0,45	disease	0,62	disease	0,55	neutral	0,47	disease	0,51	0	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,78	low_impact	-3,55	medium_impact	0,27	medium_impact	0,38	0,69	0,85	50,44	8,81	N	0,29	N	0,8	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14390	14390	C	G	MI.23598	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	284	95	G	A	gGg/gCg	-12,44	0	0	probably_damaging	1	neutral	0,38	neutral	2,43	neutral	0,66	deleterious	-5,45	medium_impact	2,29	neutral	0,83	neutral	0,65	deleterious	3,27	22,8	0,45	0,55	neutral	0,49	neutral	0,45	disease	0,52	neutral	0,45	1	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	0,09	medium_impact	0,78	0,77	0,85	50,44	8,81	N	0,36	N	0,75	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14390	14390	C	T	MI.23599	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	284	95	G	E	gGg/gAg	-12,44	0	0	probably_damaging	1	neutral	0,14	neutral	2,27	neutral	-2,55	deleterious	-7,35	high_impact	3,52	neutral	0,81	damaging	0,13	deleterious	4,1	23,7	0,29	0,45	disease	0,58	disease	0,73	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,8	low_impact	-3,55	medium_impact	-0,23	medium_impact	1,81	0,77	0,85	50,44	8,81	N	0,29	N	0,94	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8638	8638	A	T	MI.236	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	112	38	I	F	Atc/Ttc	-0,1	0	0	probably_damaging	0,99	neutral	0,16	neutral	4,25	neutral	-2,15	deleterious	-2,59	low_impact	1,73	neutral	0,92	neutral	0,55	deleterious	2,56	19,84	0,52	0,65	disease	0,62	disease	0,62	neutral	0,38	disease	0,51	0	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,75	low_impact	-2,65	medium_impact	-0,12	medium_impact	0,39	0,61	0,9	15,49	18,25	N	0,4	N	0,85	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6127	6127	T	G	MI.2360	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	224	75	I	S	aTc/aGc	6,83	1	0	probably_damaging	1	deleterious	0	neutral	2,83	neutral	-1,52	deleterious	-3,78	high_impact	4,17	neutral	0,67	neutral	0,52	deleterious	4,21	23,9	0,27	0,55	neutral	0,46	disease	0,82	disease	0,61	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,75	0,61	0,9	10,92	16,76	P	0,53	P	0,62	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14391	14391	C	G	MI.23600	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	283	95	G	R	Ggg/Cgg	-0,29	0	0	probably_damaging	1	neutral	0,18	neutral	2,27	neutral	-2,29	deleterious	-7,46	high_impact	3,52	neutral	0,78	damaging	0,08	deleterious	4,18	23,8	0,14	0,4	disease	0,66	disease	0,69	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,8	low_impact	-3,55	medium_impact	-0,16	medium_impact	1,81	0,77	0,85	50,44	8,81	N	0,26	N	0,96	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14391	14391	C	A	MI.23601	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	283	95	G	W	Ggg/Tgg	-0,29	0	0	probably_damaging	1	neutral	0,19	neutral	2,26	neutral	-2,28	deleterious	-7,6	medium_impact	3,18	neutral	0,79	damaging	0,1	deleterious	4,88	24,9	0,22	0,45	disease	0,87	disease	0,76	disease	0,66	disease	0,79	6	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,82	low_impact	-3,55	medium_impact	-0,14	medium_impact	1,52	0,52	0,8	50,44	8,81	N	0,29	N	0,98	NA	NA	0,66	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14393	14393	A	T	MI.23602	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	281	94	V	E	gTg/gAg	-7,85	0	0	benign	0,28	neutral	0,19	neutral	2,19	neutral	-2,96	deleterious	-3,68	medium_impact	2,44	neutral	0,77	neutral	0,42	deleterious	3,94	23,5	0,2	0,45	neutral	0,37	disease	0,69	disease	0,68	disease	0,74	5	neutral	0,77	neutral	0,46	neutral	-3	deleterious	0,47	medium_impact	-0,42	medium_impact	-0,14	medium_impact	0,9	0,71	0,85	49,56	8,53	N	0,33	N	0,8	NA	NA	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14393	14393	A	C	MI.23603	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	281	94	V	G	gTg/gGg	-7,85	0	0	benign	0,21	neutral	0,28	neutral	2,34	neutral	-2,4	deleterious	-4,27	low_impact	1,88	neutral	0,87	neutral	0,74	deleterious	0,78	9,36	0,26	0,45	neutral	0,41	neutral	0,45	neutral	0,44	neutral	0,47	1	neutral	0,66	deleterious	0,54	neutral	-6	neutral	0,34	medium_impact	-0,27	medium_impact	-0,02	medium_impact	0,44	0,65	0,8	49,56	8,53	N	0,45	N	0,81	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14393	14393	A	G	MI.23604	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	281	94	V	A	gTg/gCg	-7,85	0	0	benign	0,01	neutral	0,38	neutral	2,32	neutral	-0,87	neutral	-1,91	low_impact	1,74	neutral	0,93	neutral	0,92	deleterious	0,68	8,69	0,36	0,5	neutral	0,21	neutral	0,33	neutral	0,5	neutral	0,45	1	neutral	0,61	deleterious	0,69	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	0,09	medium_impact	0,32	0,66	0,8	49,56	8,53	N	0,38	N	0,43	NA	NA	0,36	rs878853104	Likely benign	not_provided	RCV000224302.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	14394	14394	C	T	MI.23605	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	280	94	V	M	Gtg/Atg	0,17	0	0	benign	0,03	neutral	0,24	neutral	2,21	neutral	-1,54	neutral	-0,04	low_impact	0,91	neutral	0,92	neutral	0,98	deleterious	0,41	6,71	0,4	0,5	neutral	0,31	neutral	0,19	neutral	0,36	neutral	0,36	3	neutral	0,75	deleterious	0,61	neutral	-6	neutral	0,13	medium_impact	0,59	medium_impact	-0,07	medium_impact	-0,38	0,77	0,85	49,56	8,53	P	0,54	P	0,6	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14394	14394	C	A	MI.23606	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	280	94	V	L	Gtg/Ttg	0,17	0	0	benign	0	neutral	0,66	neutral	2,36	neutral	0,67	neutral	0,49	neutral_impact	-0,36	neutral	0,93	neutral	0,94	neutral	-0,56	0,15	0,41	0,5	neutral	0,12	neutral	0,16	neutral	0,31	neutral	0,27	5	neutral	0,33	deleterious	0,83	neutral	-6	neutral	0,1	medium_impact	1,95	medium_impact	0,37	low_impact	-1,44	0,73	0,85	49,56	8,53	N	0,41	N	0,41	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14394	14394	C	G	MI.23607	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	280	94	V	L	Gtg/Ctg	0,17	0	0	benign	0	neutral	0,66	neutral	2,36	neutral	0,67	neutral	0,49	neutral_impact	-0,36	neutral	0,93	neutral	0,94	neutral	-0,82	0,04	0,41	0,5	neutral	0,12	neutral	0,16	neutral	0,31	neutral	0,27	5	neutral	0,33	deleterious	0,83	neutral	-6	neutral	0,1	medium_impact	1,95	medium_impact	0,37	low_impact	-1,44	0,73	0,85	49,56	8,53	N	0,38	N	0,41	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14395	14395	T	A	MI.23608	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	279	93	L	F	ttA/ttT	-6,02	0	0	possibly_damaging	0,89	neutral	0,88	neutral	2,29	neutral	-0,63	neutral	-2,29	low_impact	1,46	neutral	0,86	neutral	0,97	deleterious	2,26	17,89	0,41	0,5	neutral	0,43	neutral	0,32	neutral	0,38	neutral	0,45	1	neutral	0,88	deleterious	0,5	neutral	-3	deleterious	0,66	low_impact	-1,63	medium_impact	0,69	medium_impact	0,08	0,64	0,8	46,02	8,31	N	0,24	N	0,54	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14395	14395	T	G	MI.23609	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	279	93	L	F	ttA/ttC	-6,02	0	0	possibly_damaging	0,89	neutral	0,88	neutral	2,29	neutral	-0,63	neutral	-2,29	low_impact	1,46	neutral	0,86	neutral	0,97	deleterious	2,02	16,33	0,41	0,5	neutral	0,43	neutral	0,32	neutral	0,38	neutral	0,45	1	neutral	0,88	deleterious	0,5	neutral	-3	deleterious	0,66	low_impact	-1,63	medium_impact	0,69	medium_impact	0,08	0,64	0,8	46,02	8,31	N	0,25	N	0,54	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6127	6127	T	C	MI.2361	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	224	75	I	T	aTc/aCc	6,83	1	0	probably_damaging	1	deleterious	0	neutral	2,83	neutral	-1,73	deleterious	-3,16	high_impact	3,88	damaging	0,54	neutral	0,5	deleterious	3,39	23	0,44	0,55	neutral	0,47	disease	0,76	disease	0,59	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,48	0,65	0,9	10,92	16,76	P	0,51	P	0,76	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14396	14396	A	C	MI.23610	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	278	93	L	W	tTa/tGa	-3,27	0	0	probably_damaging	0,98	neutral	0,2	neutral	2,17	deleterious	-3,51	deleterious	-4,56	medium_impact	3,07	neutral	0,74	neutral	0,38	deleterious	3,4	23	0,14	0,4	disease	0,83	disease	0,6	disease	0,57	disease	0,71	4	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,77	low_impact	-2,35	medium_impact	-0,13	medium_impact	1,43	0,61	0,8	46,02	8,31	N	0,35	N	0,85	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14396	14396	A	G	MI.23611	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	278	93	L	S	tTa/tCa	-3,27	0	0	probably_damaging	0,92	neutral	0,45	neutral	2,23	neutral	-2,31	deleterious	-4,16	medium_impact	2,17	neutral	0,71	neutral	0,67	deleterious	3,82	23,4	0,27	0,45	disease	0,59	disease	0,57	disease	0,54	disease	0,62	2	neutral	0,92	neutral	0,27	deleterious	1	deleterious	0,73	low_impact	-1,77	medium_impact	0,16	medium_impact	0,68	0,69	0,85	46,02	8,31	N	0,3	N	0,8	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14397	14397	A	C	MI.23612	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	277	93	L	V	Tta/Gta	-0,5	0	0	benign	0,1	neutral	0,61	neutral	2,34	neutral	-1,04	neutral	-0,09	neutral_impact	0,52	neutral	0,94	neutral	0,97	deleterious	0,37	6,36	0,39	0,5	neutral	0,08	neutral	0,16	neutral	0,31	neutral	0,26	5	neutral	0,29	deleterious	0,76	neutral	-6	neutral	0,2	medium_impact	0,08	medium_impact	0,31	medium_impact	-0,7	0,63	0,8	46,02	8,31	N	0,4	N	0,14	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14397	14397	A	T	MI.23613	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	277	93	L	M	Tta/Ata	-0,5	0	0	benign	0,33	neutral	0,33	neutral	2,2	neutral	-1,58	neutral	-0,9	low_impact	1,11	neutral	0,94	neutral	0,89	neutral	1,79	14,95	0,29	0,45	neutral	0,38	neutral	0,18	neutral	0,35	neutral	0,31	4	neutral	0,6	deleterious	0,5	neutral	-6	neutral	0,41	medium_impact	-0,51	medium_impact	0,04	medium_impact	-0,21	0,73	0,85	46,02	8,31	N	0,55	P	0,55	NA	NA	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14399	14399	A	T	MI.23614	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	275	92	V	D	gTt/gAt	-8,3	0	0	possibly_damaging	0,6	neutral	0,17	neutral	2,23	deleterious	-4,26	deleterious	-3,77	medium_impact	2,32	neutral	0,71	neutral	0,4	deleterious	3,86	23,5	0,12	0,4	disease	0,7	disease	0,7	disease	0,76	disease	0,79	6	neutral	0,83	neutral	0,29	NA	0	deleterious	0,57	medium_impact	-0,96	medium_impact	-0,18	medium_impact	0,8	0,75	0,85	50	8,7	N	0,32	N	0,84	NA	NA	0,65	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14399	14399	A	G	MI.23615	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	275	92	V	A	gTt/gCt	-8,3	0	0	benign	0,15	neutral	0,62	neutral	2,33	neutral	0,36	neutral	-1,71	low_impact	1,12	neutral	0,76	neutral	0,76	deleterious	1,81	15,03	0,33	0,5	neutral	0,32	neutral	0,34	neutral	0,49	neutral	0,46	1	neutral	0,27	deleterious	0,74	neutral	-6	neutral	0,22	medium_impact	-0,11	medium_impact	0,32	medium_impact	-0,2	0,75	0,85	50	8,7	N	0,39	N	0,52	NA	NA	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14399	14399	A	C	MI.23616	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	275	92	V	G	gTt/gGt	-8,3	0	0	benign	0,31	neutral	0,48	neutral	2,27	neutral	-1,32	deleterious	-3,76	low_impact	0,88	neutral	0,83	neutral	0,71	deleterious	3,11	22,5	0,25	0,45	disease	0,58	neutral	0,46	disease	0,58	disease	0,62	2	neutral	0,43	deleterious	0,59	neutral	-6	neutral	0,43	medium_impact	-0,48	medium_impact	0,19	medium_impact	-0,4	0,79	0,85	50	8,7	N	0,3	N	0,83	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14400	14400	C	G	MI.23617	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	274	92	V	L	Gtt/Ctt	0,64	0	0	benign	0,01	neutral	1	neutral	2,35	neutral	2,18	neutral	1,42	neutral_impact	-0,7	neutral	0,95	neutral	0,89	neutral	-0,92	0,02	0,4	0,5	neutral	0,11	neutral	0,17	neutral	0,34	neutral	0,25	5	neutral	0,01	deleterious	1	neutral	-6	neutral	0,1	medium_impact	1,03	high_impact	1,87	low_impact	-1,73	0,79	0,85	50	8,7	N	0,39	N	0,33	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14400	14400	C	A	MI.23618	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	274	92	V	F	Gtt/Ttt	0,64	0	0	benign	0,01	neutral	0,93	neutral	2,3	neutral	-0,82	neutral	1,91	neutral_impact	-0,48	neutral	0,95	neutral	0,9	deleterious	0,26	5,27	0,26	0,45	neutral	0,1	neutral	0,38	neutral	0,4	neutral	0,43	1	neutral	0,04	deleterious	0,96	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,83	low_impact	-1,54	0,86	0,9	50	8,7	N	0,32	N	0,34	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14400	14400	C	T	MI.23619	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	274	92	V	I	Gtt/Att	0,64	0	0	benign	0,14	neutral	0,53	neutral	2,3	neutral	0,3	neutral	0,73	low_impact	1,08	neutral	0,81	neutral	0,68	deleterious	1,85	15,3	0,51	0,6	neutral	0,17	neutral	0,18	neutral	0,41	neutral	0,32	4	neutral	0,37	deleterious	0,7	neutral	-6	neutral	0,17	medium_impact	-0,07	medium_impact	0,24	medium_impact	-0,24	0,84	0,9	50	8,7	N	0,32	N	0,37	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6127	6127	T	A	MI.2362	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	224	75	I	N	aTc/aAc	6,83	1	0	probably_damaging	1	deleterious	0	neutral	2,77	deleterious	-3,53	deleterious	-4,44	high_impact	4,86	damaging	0,56	neutral	0,42	deleterious	4,44	24,2	0,27	0,55	disease	0,7	disease	0,81	disease	0,6	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,39	0,66	0,9	10,92	16,76	P	0,69	P	0,94	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14402	14402	C	A	MI.23620	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	272	91	S	I	aGt/aTt	-10,83	0	0	benign	0,01	neutral	0,84	neutral	2,17	neutral	-0,08	neutral	-1,27	neutral_impact	0,1	neutral	0,9	neutral	0,86	deleterious	2,62	20,3	0,32	0,5	neutral	0,13	neutral	0,45	disease	0,51	neutral	0,46	1	neutral	0,13	deleterious	0,92	neutral	-6	neutral	0,13	medium_impact	1,03	medium_impact	0,61	low_impact	-1,06	0,87	0,9	20,35	20,41	N	0,31	N	0,55	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14402	14402	C	T	MI.23621	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	272	91	S	N	aGt/aAt	-10,83	0	0	benign	0,18	neutral	0,27	neutral	2,28	neutral	0,67	neutral	-2,15	low_impact	1,56	neutral	0,77	neutral	0,65	neutral	1,01	10,69	0,51	0,6	neutral	0,27	neutral	0,26	neutral	0,42	neutral	0,44	1	neutral	0,68	deleterious	0,55	neutral	-6	neutral	0,31	medium_impact	-0,19	medium_impact	-0,03	medium_impact	0,17	0,75	0,85	20,35	20,41	N	0,42	N	0,39	NA	NA	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14402	14402	C	G	MI.23622	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	272	91	S	T	aGt/aCt	-10,83	0	0	benign	0,01	neutral	0,39	neutral	2,21	neutral	-0,28	neutral	-0,63	neutral_impact	0,76	neutral	0,89	neutral	0,93	deleterious	0,22	4,87	0,34	0,5	neutral	0,16	neutral	0,15	neutral	0,38	neutral	0,33	3	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,1	medium_impact	-0,5	0,82	0,85	20,35	20,41	N	0,41	N	0,1	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14403	14403	T	G	MI.23623	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	271	91	S	R	Agt/Cgt	-2,8	0	0	benign	0,3	neutral	0,23	neutral	2,19	neutral	-2,37	neutral	-2,33	low_impact	1,56	neutral	0,74	neutral	0,59	deleterious	2,73	21	0,2	0,45	neutral	0,25	neutral	0,47	disease	0,65	disease	0,56	1	neutral	0,72	neutral	0,47	neutral	-6	neutral	0,4	medium_impact	-0,46	medium_impact	-0,09	medium_impact	0,17	0,87	0,9	20,35	20,41	N	0,39	N	0,6	NA	NA	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14403	14403	T	A	MI.23624	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	271	91	S	C	Agt/Tgt	-2,8	0	0	benign	0,01	neutral	0,17	neutral	2,15	deleterious	-3,38	neutral	-1,64	low_impact	1,56	neutral	0,92	neutral	0,67	deleterious	0,76	9,21	0,25	0,45	neutral	0,38	neutral	0,41	neutral	0,4	neutral	0,46	1	neutral	0,83	deleterious	0,58	neutral	-6	neutral	0,16	medium_impact	1,03	medium_impact	-0,18	medium_impact	0,17	0,81	0,85	20,35	20,41	N	0,53	P	0,49	NA	NA	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14403	14403	T	C	MI.23625	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	271	91	S	G	Agt/Ggt	-2,8	0	0	benign	0	neutral	0,58	neutral	2,21	neutral	-0,36	neutral	-1,67	neutral_impact	-0,36	neutral	0,97	neutral	0,88	neutral	-0,42	0,34	0,37	0,5	neutral	0,28	neutral	0,16	neutral	0,49	neutral	0,31	4	neutral	0,42	deleterious	0,79	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,28	low_impact	-1,44	0,82	0,85	20,35	20,41	N	0,29	N	0,08	NA	NA	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14405	14405	A	G	MI.23626	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	269	90	V	A	gTg/gCg	-9,45	0	0	benign	0	neutral	0,4	neutral	2,38	neutral	0,2	neutral	2,56	neutral_impact	0,28	neutral	0,95	neutral	0,95	deleterious	0,63	8,34	0,35	0,5	neutral	0,13	neutral	0,32	neutral	0,47	neutral	0,44	1	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,11	medium_impact	-0,91	0,73	0,85	23,45	16,35	N	0,31	N	0,14	NA	NA	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14405	14405	A	C	MI.23627	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	269	90	V	G	gTg/gGg	-9,45	0	0	benign	0	neutral	0,39	neutral	2,51	neutral	-1,23	neutral	6,65	neutral_impact	-1,8	neutral	0,97	neutral	0,96	neutral	-1,21	0,01	0,29	0,45	neutral	0,14	neutral	0,24	neutral	0,43	neutral	0,42	2	neutral	0,61	deleterious	0,7	neutral	-6	neutral	0,12	medium_impact	1,95	medium_impact	0,1	low_impact	-2,65	0,7	0,85	23,45	16,35	N	0,32	N	0,22	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14405	14405	A	T	MI.23628	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	269	90	V	E	gTg/gAg	-9,45	0	0	benign	0,09	neutral	0,22	neutral	2,35	deleterious	-3,4	neutral	0,57	low_impact	0,97	neutral	0,75	neutral	0,66	deleterious	2,41	18,91	0,2	0,45	neutral	0,22	disease	0,69	disease	0,64	disease	0,69	4	neutral	0,75	deleterious	0,57	neutral	-6	neutral	0,27	medium_impact	0,13	medium_impact	-0,1	medium_impact	-0,33	0,81	0,85	23,45	16,35	N	0,39	N	0,59	NA	NA	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14406	14406	C	A	MI.23629	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	268	90	V	L	Gtg/Ttg	-0,5	0	0	benign	0,06	neutral	0,82	neutral	2,33	neutral	0,56	neutral	-0,76	neutral_impact	0,28	neutral	0,88	neutral	0,85	neutral	1,14	11,45	0,44	0,55	neutral	0,14	neutral	0,26	neutral	0,32	neutral	0,42	2	neutral	0,09	deleterious	0,88	neutral	-6	neutral	0,14	medium_impact	0,3	medium_impact	0,57	medium_impact	-0,91	0,82	0,85	23,45	16,35	N	0,27	N	0,59	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6128	6128	C	G	MI.2363	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	225	75	I	M	atC/atG	7,53	1	0	probably_damaging	1	deleterious	0,04	neutral	2,82	neutral	-2,14	neutral	-1,65	low_impact	1,82	neutral	0,64	neutral	0,56	deleterious	2,14	17,14	0,44	0,55	disease	0,52	disease	0,52	neutral	0,32	neutral	0,46	1	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,72	low_impact	-3,58	medium_impact	-0,58	medium_impact	0,58	0,83	0,9	10,92	16,76	P	0,51	P	0,76	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14406	14406	C	T	MI.23630	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	268	90	V	M	Gtg/Atg	-0,5	0	0	possibly_damaging	0,62	neutral	0,33	neutral	2,27	neutral	-1,47	neutral	0,1	neutral_impact	0,77	neutral	0,85	neutral	0,75	deleterious	3,64	23,2	0,41	0,5	neutral	0,26	neutral	0,2	neutral	0,36	neutral	0,38	2	neutral	0,7	neutral	0,36	neutral	-3	deleterious	0,48	medium_impact	-0,99	medium_impact	0,04	medium_impact	-0,5	0,83	0,85	23,45	16,35	N	0,42	N	0,55	NA	NA	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14406	14406	C	G	MI.23631	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	268	90	V	L	Gtg/Ctg	-0,5	0	0	benign	0,06	neutral	0,82	neutral	2,33	neutral	0,56	neutral	-0,76	neutral_impact	0,28	neutral	0,88	neutral	0,85	deleterious	0,79	9,4	0,44	0,55	neutral	0,14	neutral	0,26	neutral	0,32	neutral	0,42	2	neutral	0,09	deleterious	0,88	neutral	-6	neutral	0,14	medium_impact	0,3	medium_impact	0,57	medium_impact	-0,91	0,82	0,85	23,45	16,35	N	0,3	N	0,59	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14407	14407	C	A	MI.23632	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	267	89	L	F	ttG/ttT	-0,96	0	0	benign	0,1	neutral	0,86	neutral	2,14	neutral	-0,33	neutral	-0,79	low_impact	1,65	neutral	0,93	neutral	0,95	deleterious	0,8	9,46	0,41	0,5	neutral	0,18	neutral	0,32	neutral	0,35	neutral	0,44	1	neutral	0,05	deleterious	0,88	neutral	-6	neutral	0,16	medium_impact	0,08	medium_impact	0,64	medium_impact	0,24	0,64	0,8	49,12	8,71	N	0,35	N	0,32	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14407	14407	C	G	MI.23633	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	267	89	L	F	ttG/ttC	-0,96	0	0	benign	0,1	neutral	0,86	neutral	2,14	neutral	-0,33	neutral	-0,79	low_impact	1,65	neutral	0,93	neutral	0,95	deleterious	0,32	5,87	0,41	0,5	neutral	0,18	neutral	0,32	neutral	0,35	neutral	0,44	1	neutral	0,05	deleterious	0,88	neutral	-6	neutral	0,16	medium_impact	0,08	medium_impact	0,64	medium_impact	0,24	0,64	0,8	49,12	8,71	N	0,35	N	0,32	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14408	14408	A	C	MI.23634	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	266	89	L	W	tTg/tGg	-7,16	0	0	probably_damaging	0,98	neutral	0,18	neutral	2,05	neutral	-2,27	neutral	0,41	low_impact	1,52	neutral	0,88	neutral	0,91	deleterious	1,92	15,69	0,17	0,45	neutral	0,38	disease	0,59	neutral	0,4	neutral	0,49	0	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,7	low_impact	-2,35	medium_impact	-0,16	medium_impact	0,13	0,63	0,8	49,12	8,71	N	0,42	N	0,57	NA	NA	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14408	14408	A	G	MI.23635	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	266	89	L	S	tTg/tCg	-7,16	0	0	probably_damaging	0,96	neutral	0,51	neutral	2,09	neutral	-1,62	deleterious	-3,82	medium_impact	2,21	neutral	0,84	neutral	0,76	deleterious	3,74	23,3	0,27	0,45	disease	0,55	disease	0,6	disease	0,54	disease	0,6	2	neutral	0,95	neutral	0,28	deleterious	1	deleterious	0,74	low_impact	-2,06	medium_impact	0,22	medium_impact	0,71	0,82	0,85	49,12	8,71	N	0,26	N	0,85	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14409	14409	A	C	MI.23636	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	265	89	L	V	Ttg/Gtg	0,41	0	0	possibly_damaging	0,69	neutral	0,89	neutral	2,24	neutral	-0,09	neutral	-1,96	low_impact	1,82	neutral	0,85	neutral	0,88	deleterious	0,13	3,93	0,41	0,5	neutral	0,31	neutral	0,19	neutral	0,31	neutral	0,36	3	neutral	0,64	deleterious	0,6	neutral	-3	deleterious	0,56	low_impact	-1,11	medium_impact	0,71	medium_impact	0,39	0,77	0,85	49,12	8,71	N	0,29	N	0,53	NA	NA	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14409	14409	A	T	MI.23637	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	265	89	L	M	Ttg/Atg	0,41	0	0	probably_damaging	0,96	neutral	0,38	neutral	2,13	neutral	-1,45	neutral	-0,41	low_impact	1,92	neutral	0,91	neutral	0,96	deleterious	0,42	6,81	0,34	0,5	neutral	0,33	neutral	0,18	neutral	0,32	neutral	0,3	4	neutral	0,96	neutral	0,21	neutral	-2	deleterious	0,65	low_impact	-2,06	medium_impact	0,09	medium_impact	0,47	0,72	0,85	49,12	8,71	N	0,47	N	0,63	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14411	14411	A	C	MI.23638	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	263	88	V	G	gTc/gGc	-8,76	0	0	probably_damaging	0,97	neutral	0,33	neutral	1,95	deleterious	-3,32	deleterious	-6,8	medium_impact	2,02	neutral	0,76	neutral	0,75	deleterious	3,34	22,9	0,26	0,45	disease	0,75	disease	0,66	disease	0,75	disease	0,67	3	neutral	0,98	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-2,18	medium_impact	0,04	medium_impact	0,55	0,75	0,85	15,49	18,89	N	0,31	N	0,9	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14411	14411	A	G	MI.23639	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	263	88	V	A	gTc/gCc	-8,76	0	0	possibly_damaging	0,8	neutral	0,52	neutral	2,03	neutral	-1	deleterious	-3,86	low_impact	1,56	neutral	0,88	neutral	0,93	deleterious	2,25	17,87	0,32	0,5	neutral	0,46	neutral	0,44	disease	0,6	neutral	0,49	0	neutral	0,77	neutral	0,36	neutral	-3	deleterious	0,67	low_impact	-1,35	medium_impact	0,23	medium_impact	0,17	0,81	0,85	15,49	18,89	N	0,35	N	0,46	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6128	6128	C	A	MI.2364	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	225	75	I	M	atC/atA	7,53	1	0	probably_damaging	1	deleterious	0,04	neutral	2,82	neutral	-2,14	neutral	-1,65	low_impact	1,82	neutral	0,64	neutral	0,56	deleterious	2,64	20,4	0,44	0,55	disease	0,52	disease	0,52	neutral	0,32	neutral	0,46	1	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,72	low_impact	-3,58	medium_impact	-0,58	medium_impact	0,58	0,83	0,9	10,92	16,76	P	0,51	P	0,76	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14411	14411	A	T	MI.23640	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	263	88	V	D	gTc/gAc	-8,76	0	0	probably_damaging	0,98	neutral	0,15	neutral	1,93	deleterious	-4,66	deleterious	-6,55	medium_impact	3,34	neutral	0,67	neutral	0,47	deleterious	3,94	23,6	0,1	0,4	disease	0,83	disease	0,83	disease	0,82	disease	0,86	7	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,84	low_impact	-2,35	medium_impact	-0,21	medium_impact	1,66	0,8	0,85	15,49	18,89	N	0,4	N	0,92	NA	NA	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14412	14412	C	G	MI.23641	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	262	88	V	L	Gtc/Ctc	0,64	0	0	possibly_damaging	0,54	neutral	1	neutral	2,1	neutral	-0,13	neutral	-2,37	low_impact	1,36	neutral	0,85	neutral	0,7	deleterious	3,38	22,9	0,47	0,55	neutral	0,24	neutral	0,42	disease	0,54	neutral	0,48	1	neutral	0,54	deleterious	0,73	neutral	-3	deleterious	0,52	medium_impact	-0,86	high_impact	1,87	medium_impact	0	0,87	0,9	15,49	18,89	N	0,25	N	0,63	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14412	14412	C	T	MI.23642	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	262	88	V	I	Gtc/Atc	0,64	0	0	benign	0,15	neutral	0,66	neutral	2,06	neutral	0,08	neutral	-0,49	low_impact	0,92	neutral	0,93	neutral	0,93	deleterious	0,46	7,14	0,55	0,6	neutral	0,16	neutral	0,28	disease	0,53	neutral	0,46	1	neutral	0,22	deleterious	0,76	neutral	-6	neutral	0,22	medium_impact	-0,11	medium_impact	0,37	medium_impact	-0,37	0,93	0,95	15,49	18,89	N	0,32	N	0,12	NA	NA	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14412	14412	C	A	MI.23643	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	262	88	V	F	Gtc/Ttc	0,64	0	0	probably_damaging	0,96	neutral	0,77	neutral	1,98	neutral	-0,41	deleterious	-4,34	low_impact	1,84	neutral	0,79	neutral	0,65	deleterious	4,23	23,9	0,25	0,45	neutral	0,34	disease	0,72	disease	0,74	disease	0,64	3	neutral	0,95	neutral	0,41	neutral	-2	deleterious	0,71	low_impact	-2,06	medium_impact	0,5	medium_impact	0,4	0,9	0,95	15,49	18,89	N	0,25	N	0,89	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14413	14413	C	G	MI.23644	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	261	87	E	D	gaG/gaC	-1,19	0	0	benign	0,03	neutral	0,17	neutral	2,25	neutral	-0,84	neutral	-0,65	neutral_impact	0,28	neutral	0,8	neutral	0,74	deleterious	2,36	18,58	0,44	0,55	neutral	0,25	neutral	0,29	disease	0,54	neutral	0,45	1	neutral	0,82	deleterious	0,57	neutral	-6	neutral	0,12	medium_impact	0,59	medium_impact	-0,18	medium_impact	-0,91	0,93	0,95	14,6	18,39	N	0,37	N	0,6	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14413	14413	C	A	MI.23645	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	261	87	E	D	gaG/gaT	-1,19	0	0	benign	0,03	neutral	0,17	neutral	2,25	neutral	-0,84	neutral	-0,65	neutral_impact	0,28	neutral	0,8	neutral	0,74	deleterious	2,76	21,2	0,44	0,55	neutral	0,25	neutral	0,29	disease	0,54	neutral	0,45	1	neutral	0,82	deleterious	0,57	neutral	-6	neutral	0,12	medium_impact	0,59	medium_impact	-0,18	medium_impact	-0,91	0,93	0,95	14,6	18,39	N	0,38	N	0,6	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14414	14414	T	G	MI.23646	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	260	87	E	A	gAg/gCg	-3,94	0	0	benign	0,37	neutral	0,37	neutral	2,3	neutral	1,97	neutral	1,8	neutral_impact	0,62	neutral	0,91	neutral	0,98	deleterious	2,24	17,79	0,33	0,5	neutral	0,1	neutral	0,26	disease	0,51	neutral	0,43	1	neutral	0,56	deleterious	0,5	neutral	-6	neutral	0,36	medium_impact	-0,58	medium_impact	0,08	medium_impact	-0,62	0,8	0,85	14,6	18,39	N	0,37	N	0,17	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14414	14414	T	A	MI.23647	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	260	87	E	V	gAg/gTg	-3,94	0	0	benign	0,08	neutral	1	neutral	2,34	neutral	1,86	neutral	3,55	neutral_impact	-1,12	neutral	0,9	neutral	0,98	neutral	1,76	14,75	0,35	0,5	neutral	0,09	neutral	0,14	neutral	0,48	neutral	0,26	5	neutral	0,07	deleterious	0,96	neutral	-6	neutral	0,12	medium_impact	0,18	high_impact	1,87	low_impact	-2,08	0,77	0,85	14,6	18,39	N	0,37	N	0,56	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14414	14414	T	C	MI.23648	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	260	87	E	G	gAg/gGg	-3,94	0	0	benign	0,03	neutral	0,32	neutral	2,24	neutral	0,98	neutral	-0,82	low_impact	1,18	neutral	0,79	neutral	0,75	neutral	1,13	11,39	0,42	0,55	neutral	0,28	neutral	0,24	disease	0,55	neutral	0,45	1	neutral	0,66	deleterious	0,65	neutral	-6	neutral	0,12	medium_impact	0,59	medium_impact	0,03	medium_impact	-0,15	0,8	0,85	14,6	18,39	N	0,36	N	0,57	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14415	14415	C	G	MI.23649	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	259	87	E	Q	Gag/Cag	-0,73	0	0	possibly_damaging	0,82	neutral	0,17	neutral	2,26	neutral	-0,28	neutral	-0,05	low_impact	1,87	neutral	0,75	neutral	0,65	neutral	1,63	14,02	0,53	0,6	neutral	0,21	neutral	0,19	neutral	0,48	neutral	0,37	3	neutral	0,91	neutral	0,18	neutral	-3	deleterious	0,55	low_impact	-1,4	medium_impact	-0,18	medium_impact	0,43	0,93	0,95	14,6	18,39	P	0,51	P	0,54	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6129	6129	G	C	MI.2365	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	226	76	G	R	Gga/Cga	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	1,86	deleterious	-5,82	deleterious	-5,32	high_impact	5,12	damaging	0,51	damaging	0,12	deleterious	3,78	23,4	0,13	0,55	disease	0,63	disease	0,94	disease	0,79	disease	0,89	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,63	0,79	0,9	1,95	6,7	P	0,63	P	0,95	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14415	14415	C	T	MI.23650	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	259	87	E	K	Gag/Aag	-0,73	0	0	possibly_damaging	0,65	neutral	0,42	neutral	2,31	neutral	1,84	neutral	-0,13	low_impact	1,87	neutral	0,84	neutral	0,74	deleterious	4,26	23,9	0,36	0,5	neutral	0,16	neutral	0,39	disease	0,6	neutral	0,47	1	neutral	0,67	neutral	0,39	neutral	-3	deleterious	0,52	low_impact	-1,04	medium_impact	0,13	medium_impact	0,43	0,87	0,9	14,6	18,39	N	0,36	N	0,6	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14417	14417	A	C	MI.23651	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	257	86	V	G	gTt/gGt	-9,68	0	0	benign	0,14	neutral	0,33	neutral	2,23	neutral	0,6	deleterious	-3,83	low_impact	1,46	neutral	0,78	neutral	0,8	deleterious	0,5	7,43	0,28	0,45	neutral	0,29	neutral	0,49	neutral	0,49	neutral	0,47	1	neutral	0,61	deleterious	0,6	neutral	-6	neutral	0,24	medium_impact	-0,07	medium_impact	0,04	medium_impact	0,08	0,67	0,85	50,44	8,61	N	0,39	N	0,62	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14417	14417	A	T	MI.23652	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	257	86	V	D	gTt/gAt	-9,68	0	0	benign	0,35	neutral	0,21	neutral	2,22	neutral	0,1	deleterious	-3,97	medium_impact	1,98	neutral	0,76	neutral	0,7	neutral	1,49	13,26	0,21	0,45	neutral	0,24	disease	0,71	disease	0,56	disease	0,71	4	neutral	0,75	neutral	0,43	neutral	-3	deleterious	0,46	medium_impact	-0,55	medium_impact	-0,11	medium_impact	0,52	0,66	0,8	50,44	8,61	N	0,38	N	0,65	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14417	14417	A	G	MI.23653	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	257	86	V	A	gTt/gCt	-9,68	0	0	benign	0	neutral	0,51	neutral	2,28	neutral	0,8	neutral	-1,61	low_impact	1,46	neutral	0,93	neutral	0,89	deleterious	0,31	5,79	0,48	0,55	neutral	0,16	neutral	0,32	neutral	0,43	neutral	0,44	1	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,11	medium_impact	1,95	medium_impact	0,22	medium_impact	0,08	0,77	0,85	50,44	8,61	N	0,31	N	0,32	NA	NA	0,27	rs878905427	.	.	.	.	papillary thyroid carcinoma	.	.	.	.	.	.	.	.	.
chrM	14418	14418	C	A	MI.23654	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	256	86	V	F	Gtt/Ttt	-0,73	0	0	benign	0	neutral	0,71	neutral	2,22	neutral	0,23	neutral	-2,17	low_impact	1,08	neutral	0,92	neutral	0,78	deleterious	0,21	4,73	0,27	0,45	neutral	0,36	disease	0,55	neutral	0,27	neutral	0,44	1	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,14	medium_impact	1,95	medium_impact	0,42	medium_impact	-0,24	0,71	0,85	50,44	8,61	N	0,3	N	0,18	NA	NA	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14418	14418	C	T	MI.23655	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	256	86	V	I	Gtt/Att	-0,73	0	0	benign	0,01	neutral	0,4	neutral	2,26	neutral	-0,42	neutral	-0,47	low_impact	1,63	neutral	0,84	neutral	0,88	deleterious	0,25	5,22	0,6	0,65	neutral	0,24	neutral	0,18	neutral	0,43	neutral	0,33	3	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,1	medium_impact	1,03	medium_impact	0,11	medium_impact	0,23	0,75	0,85	50,44	8,61	N	0,42	N	0,07	NA	NA	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14418	14418	C	G	MI.23656	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	256	86	V	L	Gtt/Ctt	-0,73	0	0	benign	0	neutral	0,66	neutral	2,3	neutral	0,91	neutral	-0,76	low_impact	1,19	neutral	0,92	neutral	0,86	neutral	-0,29	0,68	0,48	0,55	neutral	0,19	neutral	0,28	neutral	0,24	neutral	0,44	1	neutral	0,33	deleterious	0,83	neutral	-6	neutral	0,09	medium_impact	1,95	medium_impact	0,37	medium_impact	-0,14	0,77	0,85	50,44	8,61	N	0,36	N	0,39	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14420	14420	C	T	MI.23657	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	254	85	G	E	gGg/gAg	-0,04	0	0	possibly_damaging	0,89	neutral	0,3	neutral	2,37	neutral	0,2	neutral	-0,16	low_impact	1,7	neutral	0,7	neutral	0,7	deleterious	2,3	18,18	0,36	0,5	neutral	0,13	disease	0,65	disease	0,67	disease	0,68	4	neutral	0,91	neutral	0,21	neutral	-3	deleterious	0,66	low_impact	-1,63	medium_impact	0	medium_impact	0,28	0,71	0,85	49,56	8,74	N	0,38	N	0,69	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14420	14420	C	A	MI.23658	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	254	85	G	V	gGg/gTg	-0,04	0	0	probably_damaging	0,96	neutral	0,51	neutral	2,32	neutral	-0,6	deleterious	-2,87	low_impact	1,27	neutral	0,73	neutral	0,74	deleterious	4,18	23,8	0,29	0,45	neutral	0,21	disease	0,53	disease	0,6	neutral	0,49	0	neutral	0,96	neutral	0,28	neutral	-2	deleterious	0,66	low_impact	-2,06	medium_impact	0,22	medium_impact	-0,08	0,55	0,8	49,56	8,74	N	0,29	N	0,85	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14420	14420	C	G	MI.23659	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	254	85	G	A	gGg/gCg	-0,04	0	0	possibly_damaging	0,67	neutral	0,52	neutral	2,35	neutral	0,08	neutral	-1,23	low_impact	1,45	neutral	0,75	neutral	0,81	deleterious	3,2	22,7	0,4	0,5	neutral	0,15	neutral	0,42	disease	0,54	neutral	0,48	0	neutral	0,64	neutral	0,43	neutral	-3	deleterious	0,55	low_impact	-1,08	medium_impact	0,23	medium_impact	0,08	0,77	0,85	49,56	8,74	N	0,34	N	0,65	NA	NA	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6129	6129	G	T	MI.2366	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	226	76	G	W	Gga/Tga	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	1,84	deleterious	-7,99	deleterious	-5,32	high_impact	5,12	damaging	0,52	damaging	0,15	deleterious	4,26	23,9	0,13	0,55	disease	0,86	disease	0,91	disease	0,75	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,63	0,46	0,9	1,95	6,7	P	0,56	P	0,83	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14421	14421	C	G	MI.23660	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	253	85	G	R	Ggg/Cgg	-0,5	0	0	probably_damaging	0,96	neutral	0,36	neutral	2,35	neutral	-0,01	neutral	-0,58	neutral_impact	0,53	neutral	0,74	neutral	0,74	deleterious	4,1	23,7	0,31	0,45	neutral	0,12	neutral	0,45	disease	0,66	neutral	0,48	0	neutral	0,96	neutral	0,2	neutral	-2	deleterious	0,65	low_impact	-2,06	medium_impact	0,07	medium_impact	-0,7	0,89	0,9	49,56	8,74	N	0,35	N	0,66	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14421	14421	C	A	MI.23661	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	253	85	G	W	Ggg/Tgg	-0,5	0	0	probably_damaging	0,99	neutral	0,19	neutral	2,28	neutral	-0,31	deleterious	-3,5	neutral_impact	0,18	neutral	0,68	neutral	0,76	deleterious	4,78	24,7	0,24	0,45	neutral	0,11	neutral	0,4	disease	0,66	neutral	0,48	0	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,65	low_impact	-2,63	medium_impact	-0,14	medium_impact	-0,99	0,59	0,8	49,56	8,74	N	0,36	N	0,83	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14423	14423	G	A	MI.23662	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	251	84	S	L	tCa/tTa	-2,57	0	0	probably_damaging	1	neutral	0,74	neutral	2,2	neutral	-2,2	deleterious	-5,94	high_impact	3,69	neutral	0,84	damaging	0,15	deleterious	4,31	24	0,54	0,6	disease	0,57	disease	0,82	disease	0,57	disease	0,72	4	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,8	low_impact	-3,55	medium_impact	0,46	medium_impact	1,95	0,93	0,95	42,04	7,65	N	0,21	N	0,95	NA	NA	0,55	.	.	.	.	.	.	COSM1138264	.	.	.	.	.	.	.	.
chrM	14423	14423	G	C	MI.23663	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	251	84	S	W	tCa/tGa	-2,57	0	0	probably_damaging	1	neutral	0,19	neutral	2,17	deleterious	-4,25	deleterious	-6,92	high_impact	3,69	neutral	0,79	damaging	0,11	deleterious	4,08	23,7	0,26	0,45	disease	0,9	disease	0,9	disease	0,65	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	-0,14	medium_impact	1,95	0,58	0,8	42,04	7,65	N	0,31	N	0,98	NA	NA	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14424	14424	A	G	MI.23664	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	250	84	S	P	Tca/Cca	1,79	0,06	0	probably_damaging	1	neutral	0,27	neutral	2,36	neutral	0,35	deleterious	-4,99	high_impact	3,69	neutral	0,75	damaging	0,09	deleterious	4,11	23,7	0,38	0,5	disease	0,59	disease	0,89	disease	0,58	disease	0,75	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,83	low_impact	-3,55	medium_impact	-0,03	medium_impact	1,95	0,72	0,85	42,04	7,65	N	0,34	N	0,92	NA	NA	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14424	14424	A	T	MI.23665	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	250	84	S	T	Tca/Aca	1,79	0,06	0	probably_damaging	1	neutral	0,53	neutral	2,23	neutral	-1,21	deleterious	-2,99	medium_impact	2,59	neutral	0,86	neutral	0,34	deleterious	3,35	22,9	0,38	0,5	neutral	0,42	disease	0,62	neutral	0,48	neutral	0,49	0	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,74	low_impact	-3,55	medium_impact	0,24	medium_impact	1,03	0,72	0,85	42,04	7,65	N	0,24	N	0,62	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14424	14424	A	C	MI.23666	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	250	84	S	A	Tca/Gca	1,79	0,06	0	probably_damaging	1	neutral	0,68	neutral	2,23	neutral	-1,2	deleterious	-2,99	medium_impact	2,71	neutral	0,79	damaging	0,27	deleterious	3,33	22,9	0,47	0,55	neutral	0,34	disease	0,65	neutral	0,45	disease	0,5	0	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,74	low_impact	-3,55	medium_impact	0,39	medium_impact	1,13	0,78	0,85	42,04	7,65	N	0,23	N	0,48	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14426	14426	C	A	MI.23667	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	248	83	G	V	gGg/gTg	-9,68	0	0	benign	0,04	neutral	0,52	neutral	2,25	neutral	-1,22	neutral	-0,88	neutral_impact	0,6	neutral	0,88	neutral	0,94	deleterious	0	2,62	0,32	0,5	neutral	0,19	disease	0,73	neutral	0,47	disease	0,55	1	neutral	0,44	deleterious	0,74	neutral	-6	neutral	0,19	medium_impact	0,47	medium_impact	0,23	medium_impact	-0,64	0,7	0,85	49,12	8,61	N	0,29	N	0,3	NA	NA	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14426	14426	C	G	MI.23668	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	248	83	G	A	gGg/gCg	-9,68	0	0	possibly_damaging	0,46	neutral	0,54	neutral	2,29	neutral	-0,52	neutral	-1,07	medium_impact	2,36	neutral	0,85	neutral	0,88	deleterious	0,39	6,56	0,51	0,6	neutral	0,26	disease	0,72	disease	0,54	disease	0,55	1	neutral	0,44	deleterious	0,54	NA	0	deleterious	0,49	medium_impact	-0,73	medium_impact	0,25	medium_impact	0,84	0,78	0,85	49,12	8,61	N	0,27	N	0,3	NA	NA	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14426	14426	C	T	MI.23669	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	248	83	G	E	gGg/gAg	-9,68	0	0	probably_damaging	0,91	neutral	0,31	neutral	2,31	neutral	-0,09	deleterious	-3,15	medium_impact	2,7	neutral	0,62	neutral	0,42	deleterious	2,84	21,6	0,35	0,5	neutral	0,4	disease	0,86	disease	0,67	disease	0,71	4	neutral	0,92	neutral	0,2	deleterious	1	deleterious	0,77	low_impact	-1,72	medium_impact	0,01	medium_impact	1,12	0,77	0,85	49,12	8,61	N	0,34	N	0,9	NA	NA	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6130	6130	G	T	MI.2367	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	227	76	G	V	gGa/gTa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	1,85	deleterious	-6,37	deleterious	-5,99	high_impact	5,12	damaging	0,49	damaging	0,16	deleterious	3,69	23,3	0,12	0,55	neutral	0,32	disease	0,93	disease	0,71	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,63	0,68	0,9	1,95	6,7	P	0,56	P	0,93	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14427	14427	C	A	MI.23670	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	247	83	G	W	Ggg/Tgg	-0,96	0	0	probably_damaging	0,97	neutral	0,21	neutral	2,24	neutral	-1,71	deleterious	-3,73	medium_impact	2,82	neutral	0,62	neutral	0,42	deleterious	4,8	24,8	0,28	0,45	disease	0,8	disease	0,89	disease	0,7	disease	0,78	6	neutral	0,98	neutral	0,12	deleterious	1	deleterious	0,83	low_impact	-2,18	medium_impact	-0,11	medium_impact	1,22	0,57	0,8	49,12	8,61	N	0,29	N	0,82	NA	NA	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14427	14427	C	G	MI.23671	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	247	83	G	R	Ggg/Cgg	-0,96	0	0	probably_damaging	0,93	neutral	0,36	neutral	2,32	neutral	-0,06	deleterious	-3,58	medium_impact	2,96	damaging	0,6	neutral	0,36	deleterious	2,99	22,2	0,33	0,5	neutral	0,45	disease	0,81	disease	0,67	disease	0,68	4	neutral	0,94	neutral	0,22	deleterious	1	deleterious	0,78	low_impact	-1,83	medium_impact	0,07	medium_impact	1,34	0,97	1	49,12	8,61	N	0,33	N	0,89	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14428	14428	C	A	MI.23672	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	246	82	W	C	tgG/tgT	-0,73	0	0	probably_damaging	1	neutral	0,16	neutral	2,3	deleterious	-5,28	deleterious	-12,79	high_impact	3,94	neutral	0,63	damaging	0,05	deleterious	4,65	24,5	0,32	0,5	disease	0,87	disease	0,93	disease	0,81	disease	0,89	8	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,19	high_impact	2,16	0,28	0,8	15,49	18,3	N	0,45	N	0,96	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14428	14428	C	G	MI.23673	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	246	82	W	C	tgG/tgC	-0,73	0	0	probably_damaging	1	neutral	0,16	neutral	2,3	deleterious	-5,28	deleterious	-12,79	high_impact	3,94	neutral	0,63	damaging	0,05	deleterious	4,31	24	0,32	0,5	disease	0,87	disease	0,93	disease	0,81	disease	0,89	8	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,19	high_impact	2,16	0,28	0,8	15,49	18,3	N	0,45	N	0,96	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14429	14429	C	G	MI.23674	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	245	82	W	S	tGg/tCg	-3,94	0	0	probably_damaging	1	neutral	0,42	neutral	2,4	deleterious	-3,12	deleterious	-13,79	high_impact	3,6	neutral	0,63	damaging	0,08	deleterious	4,26	23,9	0,33	0,5	disease	0,67	disease	0,95	disease	0,79	disease	0,9	8	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-3,55	medium_impact	0,13	medium_impact	1,88	0,31	0,8	15,49	18,3	N	0,43	N	0,92	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14429	14429	C	A	MI.23675	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	245	82	W	L	tGg/tTg	-3,94	0	0	probably_damaging	1	neutral	0,72	neutral	2,38	neutral	-2,26	deleterious	-12,73	medium_impact	2,47	neutral	0,83	neutral	0,41	deleterious	4,71	24,6	0,26	0,45	disease	0,62	disease	0,84	disease	0,68	disease	0,56	1	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,84	low_impact	-3,55	medium_impact	0,43	medium_impact	0,93	0,28	0,8	15,49	18,3	N	0,28	N	0,95	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14430	14430	A	C	MI.23676	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	244	82	W	G	Tgg/Ggg	0,64	0,06	0	probably_damaging	1	neutral	0,35	neutral	2,36	deleterious	-4,06	deleterious	-12,83	medium_impact	3,4	neutral	0,64	damaging	0,09	deleterious	3,77	23,4	0,35	0,5	disease	0,72	disease	0,91	disease	0,8	disease	0,85	7	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,85	low_impact	-3,55	medium_impact	0,06	medium_impact	1,71	0,25	0,8	15,49	18,3	N	0,46	N	0,9	NA	NA	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14430	14430	A	G	MI.23677	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	244	82	W	R	Tgg/Cgg	0,64	0,06	0	probably_damaging	1	neutral	0,34	neutral	2,38	deleterious	-3,33	deleterious	-13,79	high_impact	3,94	neutral	0,61	damaging	0,06	deleterious	3,79	23,4	0,43	0,55	disease	0,73	disease	0,93	disease	0,79	disease	0,84	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	0,05	high_impact	2,16	0,25	0,8	15,49	18,3	P	0,54	P	0,96	NA	NA	0,76	.	.	.	.	.	.	.	.	.	A14430G	Thyroid Cancer	+	-	Reported	1
chrM	14432	14432	G	T	MI.23678	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	242	81	A	E	gCa/gAa	-3,49	0	0	possibly_damaging	0,77	neutral	0,49	neutral	2,34	neutral	0,38	neutral	-2,49	medium_impact	2,77	neutral	0,75	neutral	0,45	deleterious	3,59	23,2	0,35	0,5	neutral	0,48	disease	0,8	disease	0,57	disease	0,76	5	neutral	0,75	neutral	0,36	NA	0	deleterious	0,7	low_impact	-1,28	medium_impact	0,2	medium_impact	1,18	0,86	0,9	26,99	25,17	N	0,26	N	0,75	NA	NA	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14432	14432	G	C	MI.23679	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	242	81	A	G	gCa/gGa	-3,49	0	0	possibly_damaging	0,46	neutral	0,46	neutral	2,28	neutral	-1,23	deleterious	-2,79	low_impact	1,62	neutral	0,78	neutral	0,7	deleterious	2,12	16,96	0,31	0,45	neutral	0,5	neutral	0,43	neutral	0,27	neutral	0,32	4	neutral	0,51	deleterious	0,5	neutral	-3	deleterious	0,55	medium_impact	-0,73	medium_impact	0,17	medium_impact	0,22	0,85	0,9	26,99	25,17	N	0,3	N	0,51	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6130	6130	G	C	MI.2368	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	227	76	G	A	gGa/gCa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	1,95	deleterious	-3,86	deleterious	-3,99	high_impact	3,81	neutral	0,66	neutral	0,3	deleterious	3	22,2	0,22	0,55	neutral	0,31	disease	0,81	disease	0,61	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,42	0,68	0,9	1,95	6,7	N	0,46	N	0,64	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14432	14432	G	A	MI.23680	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	242	81	A	V	gCa/gTa	-3,49	0	0	possibly_damaging	0,58	neutral	0,57	neutral	2,33	neutral	0,23	neutral	-0,28	low_impact	1,29	neutral	0,86	neutral	0,9	deleterious	0,34	6,1	0,44	0,55	neutral	0,17	disease	0,53	neutral	0,32	neutral	0,46	1	neutral	0,53	deleterious	0,5	neutral	-3	deleterious	0,5	medium_impact	-0,92	medium_impact	0,27	medium_impact	-0,06	0,85	0,9	26,99	25,17	N	0,25	N	0,12	NA	NA	0,2	.	.	.	.	.	.	COSM5654576	.	.	.	.	.	.	.	.
chrM	14433	14433	C	G	MI.23681	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	241	81	A	P	Gca/Cca	-0,04	0	0	probably_damaging	0,91	neutral	0,26	neutral	2,28	neutral	-1,41	deleterious	-2,59	medium_impact	2,77	neutral	0,78	neutral	0,32	deleterious	4,03	23,7	0,29	0,45	disease	0,61	disease	0,86	disease	0,54	disease	0,77	5	neutral	0,93	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-1,72	medium_impact	-0,05	medium_impact	1,18	0,89	0,9	26,99	25,17	N	0,26	N	0,78	NA	NA	0,66	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14433	14433	C	A	MI.23682	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	241	81	A	S	Gca/Tca	-0,04	0	0	benign	0,18	neutral	0,73	neutral	2,36	neutral	0,6	neutral	-0,88	neutral_impact	0,78	neutral	0,88	neutral	0,94	deleterious	0,49	7,36	0,45	0,55	neutral	0,36	neutral	0,24	neutral	0,21	neutral	0,45	1	neutral	0,16	deleterious	0,78	neutral	-6	neutral	0,22	medium_impact	-0,19	medium_impact	0,45	medium_impact	-0,49	0,89	0,9	26,99	25,17	N	0,34	N	0,59	NA	NA	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14433	14433	C	T	MI.23683	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	241	81	A	T	Gca/Aca	-0,04	0	0	benign	0,02	neutral	0,54	neutral	2,34	neutral	0,34	neutral	0,28	neutral_impact	0,35	neutral	0,97	neutral	0,96	neutral	-0,15	1,39	0,55	0,6	neutral	0,24	neutral	0,33	neutral	0,24	neutral	0,45	1	neutral	0,43	deleterious	0,76	neutral	-6	neutral	0,13	medium_impact	0,75	medium_impact	0,25	medium_impact	-0,85	0,87	0,9	26,99	25,17	N	0,34	N	0,3	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14434	14434	C	A	MI.23684	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	240	80	E	D	gaG/gaT	-0,5	0	0	benign	0,24	neutral	0,57	neutral	2,19	neutral	-2,38	deleterious	-2,97	medium_impact	2,77	neutral	0,78	neutral	0,4	deleterious	4,11	23,7	0,44	0,55	neutral	0,35	disease	0,82	neutral	0,49	disease	0,65	3	neutral	0,32	deleterious	0,67	neutral	-3	neutral	0,34	medium_impact	-0,34	medium_impact	0,27	medium_impact	1,18	0,84	0,9	25,66	23,52	N	0,24	N	0,83	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14434	14434	C	G	MI.23685	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	240	80	E	D	gaG/gaC	-0,5	0	0	benign	0,24	neutral	0,57	neutral	2,19	neutral	-2,38	deleterious	-2,97	medium_impact	2,77	neutral	0,78	neutral	0,4	deleterious	3,89	23,5	0,44	0,55	neutral	0,35	disease	0,82	neutral	0,49	disease	0,65	3	neutral	0,32	deleterious	0,67	neutral	-3	neutral	0,34	medium_impact	-0,34	medium_impact	0,27	medium_impact	1,18	0,84	0,9	25,66	23,52	N	0,25	N	0,83	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14435	14435	T	A	MI.23686	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	239	80	E	V	gAg/gTg	-0,73	0	0	probably_damaging	0,98	neutral	0,28	neutral	2,19	deleterious	-3,87	deleterious	-6,97	medium_impact	3,12	neutral	0,69	neutral	0,49	deleterious	4,58	24,4	0,38	0,5	disease	0,66	disease	0,9	disease	0,55	disease	0,57	1	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,86	low_impact	-2,35	medium_impact	-0,02	medium_impact	1,47	0,85	0,9	25,66	23,52	N	0,34	N	0,72	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14435	14435	T	C	MI.23687	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	239	80	E	G	gAg/gGg	-0,73	0	0	probably_damaging	0,96	neutral	0,37	neutral	2,19	deleterious	-3,55	deleterious	-6,96	medium_impact	2,89	neutral	0,67	neutral	0,5	deleterious	4,18	23,8	0,5	0,6	disease	0,55	disease	0,84	disease	0,59	disease	0,69	4	neutral	0,96	neutral	0,21	deleterious	1	deleterious	0,81	low_impact	-2,06	medium_impact	0,08	medium_impact	1,28	0,8	0,85	25,66	23,52	N	0,29	N	0,29	NA	NA	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14435	14435	T	G	MI.23688	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	239	80	E	A	gAg/gCg	-0,73	0	0	probably_damaging	0,93	neutral	0,7	neutral	2,23	neutral	-2,68	deleterious	-5,97	medium_impact	3,12	neutral	0,65	neutral	0,49	deleterious	4,05	23,7	0,41	0,5	neutral	0,47	disease	0,84	disease	0,57	disease	0,69	4	neutral	0,92	neutral	0,39	deleterious	1	deleterious	0,8	low_impact	-1,83	medium_impact	0,41	medium_impact	1,47	0,77	0,85	25,66	23,52	N	0,28	N	0,64	NA	NA	0,69	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14436	14436	C	G	MI.23689	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	238	80	E	Q	Gag/Cag	1,79	0,07	0	probably_damaging	0,97	neutral	0,54	neutral	2,21	neutral	-2,8	deleterious	-2,99	medium_impact	3,03	neutral	0,72	neutral	0,48	deleterious	3,61	23,2	0,52	0,6	neutral	0,45	disease	0,79	disease	0,53	disease	0,55	1	neutral	0,96	neutral	0,29	deleterious	1	deleterious	0,79	low_impact	-2,18	medium_impact	0,25	medium_impact	1,4	0,91	0,95	25,66	23,52	N	0,31	N	0,87	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6130	6130	G	A	MI.2369	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	227	76	G	E	gGa/gAa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	1,87	deleterious	-5,37	deleterious	-5,32	high_impact	4,78	damaging	0,46	damaging	0,16	deleterious	3,74	23,3	0,16	0,55	neutral	0,47	disease	0,9	disease	0,78	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,32	0,7	0,9	1,95	6,7	P	0,68	P	0,93	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14436	14436	C	T	MI.23690	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	238	80	E	K	Gag/Aag	1,79	0,07	0	probably_damaging	0,93	neutral	0,86	neutral	2,31	neutral	-2,02	deleterious	-3,99	medium_impact	3,12	neutral	0,78	neutral	0,4	deleterious	4,76	24,7	0,62	0,65	neutral	0,25	disease	0,9	disease	0,6	disease	0,71	4	neutral	0,92	neutral	0,47	deleterious	1	deleterious	0,79	low_impact	-1,83	medium_impact	0,64	medium_impact	1,47	0,93	0,95	25,66	23,52	N	0,33	N	0,93	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14438	14438	G	T	MI.23691	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	236	79	P	H	cCt/cAt	-1,42	0	0	probably_damaging	1	neutral	0,52	neutral	2,27	deleterious	-5,4	deleterious	-8,97	high_impact	3,65	damaging	0,52	damaging	0,06	deleterious	3,54	23,1	0,42	0,55	disease	0,92	disease	0,89	disease	0,73	disease	0,83	7	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0,23	medium_impact	1,92	0,59	0,8	49,56	8,5	N	0,36	N	0,73	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14438	14438	G	C	MI.23692	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	236	79	P	R	cCt/cGt	-1,42	0	0	probably_damaging	1	neutral	0,36	neutral	2,29	deleterious	-4,07	deleterious	-8,98	high_impact	4	damaging	0,44	damaging	0,06	deleterious	3,36	22,9	0,36	0,5	disease	0,86	disease	0,91	disease	0,71	disease	0,81	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	0,07	high_impact	2,21	0,57	0,8	49,56	8,5	N	0,43	N	0,66	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14438	14438	G	A	MI.23693	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	236	79	P	L	cCt/cTt	-1,42	0	0	probably_damaging	1	neutral	0,67	neutral	2,33	deleterious	-4,49	deleterious	-9,97	medium_impact	3,31	damaging	0,55	damaging	0,07	deleterious	4,07	23,7	0,37	0,5	disease	0,85	disease	0,91	disease	0,64	disease	0,77	5	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,91	low_impact	-3,55	medium_impact	0,38	medium_impact	1,63	0,71	0,85	49,56	8,5	N	0,32	N	0,96	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14439	14439	G	A	MI.23694	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	235	79	P	S	Cct/Tct	3,63	0,99	0	probably_damaging	1	neutral	0,47	neutral	2,37	deleterious	-3,64	deleterious	-7,98	high_impact	4	damaging	0,51	damaging	0,08	deleterious	3,62	23,2	0,42	0,5	disease	0,77	disease	0,9	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	0,18	high_impact	2,21	0,49	0,8	49,56	8,5	P	0,55	P	0,79	NA	NA	0,74	.	.	.	.	.	.	.	.	.	G14439A	Mitochondrial Respiratory Chain Disorder	+	-	Reported	1
chrM	14439	14439	G	C	MI.23695	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	235	79	P	A	Cct/Gct	3,63	0,99	0	probably_damaging	1	neutral	0,54	neutral	2,33	deleterious	-3,5	deleterious	-7,98	high_impact	4	damaging	0,54	damaging	0,1	deleterious	2,78	21,3	0,3	0,45	disease	0,74	disease	0,81	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,55	medium_impact	0,25	high_impact	2,21	0,65	0,8	49,56	8,5	N	0,52	P	0,71	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14439	14439	G	T	MI.23696	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	235	79	P	T	Cct/Act	3,63	0,99	0	probably_damaging	1	neutral	0,42	neutral	2,46	deleterious	-4,07	deleterious	-7,98	high_impact	4	damaging	0,52	damaging	0,07	deleterious	3,21	22,7	0,38	0,5	disease	0,81	disease	0,89	disease	0,69	disease	0,77	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0,13	high_impact	2,21	0,71	0,85	49,56	8,5	N	0,42	N	0,88	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14441	14441	T	C	MI.23697	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	233	78	Y	C	tAt/tGt	-1,19	0	0	probably_damaging	0,99	neutral	0,15	neutral	2,28	deleterious	-6,14	deleterious	-8,85	medium_impact	3,29	damaging	0,49	damaging	0,16	deleterious	3,38	22,9	0,36	0,5	disease	0,84	disease	0,89	disease	0,74	disease	0,82	6	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,88	low_impact	-2,63	medium_impact	-0,21	medium_impact	1,62	0,1	0,8	49,56	8,89	N	0,35	N	1	NA	NA	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14441	14441	T	G	MI.23698	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	233	78	Y	S	tAt/tCt	-1,19	0	0	probably_damaging	0,95	neutral	0,42	neutral	2,41	deleterious	-4,3	deleterious	-8,81	high_impact	3,83	damaging	0,49	neutral	0,29	deleterious	3,94	23,5	0,35	0,5	disease	0,6	disease	0,88	disease	0,71	disease	0,79	6	neutral	0,94	neutral	0,24	deleterious	2	deleterious	0,84	low_impact	-1,97	medium_impact	0,13	high_impact	2,07	0,28	0,8	49,56	8,89	N	0,42	N	0,96	NA	NA	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14441	14441	T	A	MI.23699	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	233	78	Y	F	tAt/tTt	-1,19	0	0	possibly_damaging	0,9	neutral	0,79	neutral	2,34	neutral	-1,04	deleterious	-3,94	medium_impact	2,22	neutral	0,82	neutral	0,66	deleterious	3,66	23,2	0,39	0,5	neutral	0,24	neutral	0,42	disease	0,54	neutral	0,4	2	neutral	0,88	neutral	0,45	NA	0	deleterious	0,71	low_impact	-1,67	medium_impact	0,53	medium_impact	0,72	0,38	0,8	49,56	8,89	N	0,23	N	0,8	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8638	8638	A	G	MI.237	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	112	38	I	V	Atc/Gtc	-0,1	0	0	probably_damaging	0,93	neutral	0,27	neutral	4,48	neutral	0,63	neutral	-0,59	low_impact	0,92	neutral	0,91	neutral	0,97	neutral	1,46	13,1	0,63	0,7	neutral	0,32	neutral	0,16	neutral	0,3	neutral	0,3	4	neutral	0,94	neutral	0,17	neutral	-2	deleterious	0,59	low_impact	-1,82	medium_impact	0,05	medium_impact	-0,31	0,39	0,9	15,49	18,25	N	0,45	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6132	6132	G	A	MI.2370	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	229	77	G	S	Ggc/Agc	-4,73	0	0	probably_damaging	1	deleterious	0	neutral	2,12	deleterious	-4,2	deleterious	-4	high_impact	4,82	damaging	0,59	damaging	0,18	deleterious	4,05	23,7	0,25	0,55	disease	0,62	disease	0,83	disease	0,65	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,35	0,7	0,9	2,14	6,61	P	0,63	P	0,73	polymorphism	0,51	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14442	14442	A	G	MI.23700	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	232	78	Y	H	Tat/Cat	0,64	0,02	0	benign	0,14	neutral	0,5	neutral	2,31	deleterious	-4,37	deleterious	-4,71	medium_impact	2	neutral	0,81	neutral	0,61	neutral	1,69	14,36	0,55	0,6	disease	0,61	disease	0,74	disease	0,7	disease	0,63	3	neutral	0,41	deleterious	0,68	neutral	-3	neutral	0,34	medium_impact	-0,07	medium_impact	0,21	medium_impact	0,54	0,27	0,8	49,56	8,89	N	0,26	N	0,98	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14442	14442	A	T	MI.23701	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	232	78	Y	N	Tat/Aat	0,64	0,02	0	probably_damaging	0,93	neutral	0,27	neutral	2,33	deleterious	-4,84	deleterious	-8,77	high_impact	3,83	damaging	0,55	damaging	0,27	deleterious	3,52	23,1	0,39	0,5	disease	0,66	disease	0,9	disease	0,72	disease	0,8	6	neutral	0,94	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-1,83	medium_impact	-0,03	high_impact	2,07	0,22	0,8	49,56	8,89	N	0,42	N	1	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14442	14442	A	C	MI.23702	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	232	78	Y	D	Tat/Gat	0,64	0,02	0	probably_damaging	0,96	neutral	0,2	neutral	2,32	deleterious	-4,01	deleterious	-9,79	medium_impact	3,48	damaging	0,53	neutral	0,3	deleterious	3,51	23,1	0,32	0,5	neutral	0,35	disease	0,91	disease	0,73	disease	0,8	6	neutral	0,97	neutral	0,12	deleterious	1	deleterious	0,81	low_impact	-2,06	medium_impact	-0,13	medium_impact	1,78	0,32	0,8	49,56	8,89	N	0,41	N	0,97	NA	NA	0,62	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14443	14443	C	G	MI.23703	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	231	77	E	D	gaG/gaC	2,94	0,04	0	probably_damaging	1	neutral	0,25	neutral	2,17	neutral	-1,63	neutral	-2,35	medium_impact	2,6	neutral	0,79	neutral	0,41	deleterious	2,83	21,5	0,42	0,55	neutral	0,24	disease	0,69	neutral	0,49	disease	0,52	0	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,74	low_impact	-3,55	medium_impact	-0,06	medium_impact	1,04	0,78	0,85	27,43	20,89	N	0,36	N	0,82	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14443	14443	C	A	MI.23704	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	231	77	E	D	gaG/gaT	2,94	0,04	0	probably_damaging	1	neutral	0,25	neutral	2,17	neutral	-1,63	neutral	-2,35	medium_impact	2,6	neutral	0,79	neutral	0,41	deleterious	3,07	22,4	0,42	0,55	neutral	0,24	disease	0,69	neutral	0,49	disease	0,52	0	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,74	low_impact	-3,55	medium_impact	-0,06	medium_impact	1,04	0,78	0,85	27,43	20,89	N	0,38	N	0,82	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14444	14444	T	C	MI.23705	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	230	77	E	G	gAg/gGg	-6,47	0	0	probably_damaging	1	neutral	0,35	neutral	2,14	neutral	-2,48	deleterious	-5,32	medium_impact	3,4	neutral	0,65	damaging	0,17	deleterious	4,23	23,9	0,49	0,55	neutral	0,34	disease	0,71	disease	0,59	disease	0,72	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	0,06	medium_impact	1,71	0,72	0,85	27,43	20,89	N	0,32	N	0,73	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14444	14444	T	A	MI.23706	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	230	77	E	V	gAg/gTg	-6,47	0	0	probably_damaging	1	neutral	0,52	neutral	2,14	neutral	-2,74	deleterious	-5,3	medium_impact	2,6	neutral	0,75	neutral	0,32	deleterious	4,75	24,7	0,35	0,5	neutral	0,35	disease	0,81	disease	0,58	disease	0,77	5	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,77	low_impact	-3,55	medium_impact	0,23	medium_impact	1,04	0,85	0,9	27,43	20,89	N	0,28	N	0,82	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14444	14444	T	G	MI.23707	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	230	77	E	A	gAg/gCg	-6,47	0	0	probably_damaging	1	neutral	0,57	neutral	2,17	neutral	-1,72	deleterious	-4,33	medium_impact	2,36	neutral	0,67	neutral	0,37	deleterious	4,02	23,6	0,4	0,5	neutral	0,21	disease	0,61	neutral	0,49	neutral	0,45	1	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,73	low_impact	-3,55	medium_impact	0,27	medium_impact	0,84	0,76	0,85	27,43	20,89	N	0,26	N	0,63	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14445	14445	C	T	MI.23708	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	229	77	E	K	Gag/Aag	-0,04	0	0	probably_damaging	1	neutral	0,37	neutral	2,42	neutral	0,57	neutral	-2,47	medium_impact	3,4	neutral	0,68	neutral	0,29	deleterious	4,8	24,8	0,46	0,55	neutral	0,13	disease	0,77	disease	0,56	disease	0,74	5	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,74	low_impact	-3,55	medium_impact	0,08	medium_impact	1,71	0,9	0,95	27,43	20,89	N	0,34	N	0,76	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14445	14445	C	G	MI.23709	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	229	77	E	Q	Gag/Cag	-0,04	0	0	probably_damaging	1	neutral	0,33	neutral	2,2	neutral	-1,22	neutral	-0,64	low_impact	1,65	neutral	0,85	neutral	0,83	deleterious	2	16,24	0,53	0,6	neutral	0,16	neutral	0,43	neutral	0,25	neutral	0,41	2	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,69	low_impact	-3,55	medium_impact	0,04	medium_impact	0,24	0,87	0,9	27,43	20,89	N	0,37	N	0,06	NA	NA	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6132	6132	G	C	MI.2371	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	229	77	G	R	Ggc/Cgc	-4,73	0	0	probably_damaging	1	deleterious	0	neutral	2,05	deleterious	-7,56	deleterious	-5,34	high_impact	5,17	damaging	0,51	damaging	0,12	deleterious	3,86	23,5	0,13	0,55	disease	0,78	disease	0,93	disease	0,77	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,8	0,9	2,14	6,61	P	0,57	P	0,95	disease_causing	0,67	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14446	14446	C	G	MI.23710	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	228	76	E	D	gaG/gaC	-0,04	0	0	benign	0,05	neutral	0,58	neutral	2,3	neutral	-1,12	deleterious	-2,52	low_impact	1,04	neutral	0,88	neutral	0,79	deleterious	2,76	21,1	0,33	0,5	neutral	0,17	disease	0,52	neutral	0,32	neutral	0,42	2	neutral	0,36	deleterious	0,77	neutral	-6	neutral	0,19	medium_impact	0,38	medium_impact	0,28	medium_impact	-0,27	0,85	0,9	18,58	16,92	N	0,3	N	0,83	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14446	14446	C	A	MI.23711	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	228	76	E	D	gaG/gaT	-0,04	0	0	benign	0,05	neutral	0,58	neutral	2,3	neutral	-1,12	deleterious	-2,52	low_impact	1,04	neutral	0,88	neutral	0,79	deleterious	3,01	22,3	0,33	0,5	neutral	0,17	disease	0,52	neutral	0,32	neutral	0,42	2	neutral	0,36	deleterious	0,77	neutral	-6	neutral	0,19	medium_impact	0,38	medium_impact	0,28	medium_impact	-0,27	0,85	0,9	18,58	16,92	N	0,3	N	0,83	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14447	14447	T	G	MI.23712	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	227	76	E	A	gAg/gCg	-3,26	0	0	possibly_damaging	0,86	neutral	0,65	neutral	2,29	deleterious	-3,57	deleterious	-5,84	high_impact	3,73	neutral	0,7	neutral	0,61	deleterious	4,04	23,7	0,31	0,45	neutral	0,42	disease	0,85	disease	0,68	disease	0,75	5	neutral	0,84	neutral	0,4	deleterious	1	deleterious	0,76	low_impact	-1,52	medium_impact	0,36	medium_impact	1,99	0,78	0,85	18,58	16,92	N	0,32	N	0,64	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14447	14447	T	A	MI.23713	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	227	76	E	V	gAg/gTg	-3,26	0	0	probably_damaging	0,96	neutral	0,28	neutral	2,43	deleterious	-5,07	deleterious	-6,84	high_impact	3,73	neutral	0,66	neutral	0,51	deleterious	4,57	24,4	0,24	0,45	disease	0,64	disease	0,92	disease	0,72	disease	0,8	6	neutral	0,97	neutral	0,16	deleterious	2	deleterious	0,86	low_impact	-2,06	medium_impact	-0,02	medium_impact	1,99	0,78	0,85	18,58	16,92	N	0,38	N	0,72	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14447	14447	T	C	MI.23714	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	227	76	E	G	gAg/gGg	-3,26	0	0	possibly_damaging	0,86	neutral	0,35	neutral	2,26	deleterious	-3,91	deleterious	-6,7	medium_impact	3,39	neutral	0,7	neutral	0,78	deleterious	4,17	23,8	0,38	0,5	neutral	0,49	disease	0,87	disease	0,7	disease	0,77	5	neutral	0,88	neutral	0,25	NA	0	deleterious	0,77	low_impact	-1,52	medium_impact	0,06	medium_impact	1,7	0,81	0,85	18,58	16,92	N	0,37	N	0,29	NA	NA	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14448	14448	C	G	MI.23715	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	226	76	E	Q	Gag/Cag	2,25	0,97	0	probably_damaging	0,94	neutral	0,5	neutral	2,26	deleterious	-3,52	deleterious	-2,92	high_impact	3,73	neutral	0,71	neutral	0,48	deleterious	3,58	23,2	0,4	0,5	neutral	0,41	disease	0,83	disease	0,69	disease	0,73	5	neutral	0,93	neutral	0,28	deleterious	2	deleterious	0,77	low_impact	-1,89	medium_impact	0,21	medium_impact	1,99	0,74	0,85	18,58	16,92	N	0,49	N	0,87	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14448	14448	C	T	MI.23716	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	226	76	E	K	Gag/Aag	2,25	0,97	0	possibly_damaging	0,86	neutral	0,8	neutral	2,3	deleterious	-3,33	deleterious	-3,92	medium_impact	3,39	neutral	0,69	neutral	0,37	deleterious	4,74	24,7	0,39	0,5	neutral	0,27	disease	0,92	disease	0,66	disease	0,77	5	neutral	0,84	deleterious	0,47	NA	0	deleterious	0,78	low_impact	-1,52	medium_impact	0,54	medium_impact	1,7	0,9	0,95	18,58	16,92	N	0,44	N	0,93	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14449	14449	A	T	MI.23717	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	225	75	I	M	atT/atA	4,31	0,98	0	probably_damaging	0,97	neutral	0,21	neutral	2,3	neutral	-1,18	neutral	0,29	low_impact	1,02	neutral	0,84	neutral	0,83	neutral	1,77	14,83	0,65	0,7	neutral	0,36	disease	0,51	neutral	0,11	neutral	0,43	1	deleterious	0,98	neutral	0,12	neutral	-2	deleterious	0,68	low_impact	-2,18	medium_impact	-0,11	medium_impact	-0,29	0,72	0,85	50,44	8,5	P	0,58	P	0,71	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14449	14449	A	C	MI.23718	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	225	75	I	M	atT/atG	4,31	0,98	0	probably_damaging	0,97	neutral	0,21	neutral	2,3	neutral	-1,18	neutral	0,29	low_impact	1,02	neutral	0,84	neutral	0,83	neutral	1,63	14,02	0,65	0,7	neutral	0,36	disease	0,51	neutral	0,11	neutral	0,43	1	deleterious	0,98	neutral	0,12	neutral	-2	deleterious	0,68	low_impact	-2,18	medium_impact	-0,11	medium_impact	-0,29	0,72	0,85	50,44	8,5	P	0,56	P	0,71	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14450	14450	A	T	MI.23719	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	224	75	I	N	aTt/aAt	-6,7	0	0	probably_damaging	0,98	neutral	0,61	neutral	2,44	neutral	2,13	neutral	-0,72	medium_impact	2,34	neutral	0,64	neutral	0,54	deleterious	4,16	23,8	0,46	0,55	neutral	0,4	disease	0,88	neutral	0,41	disease	0,77	5	neutral	0,98	neutral	0,32	deleterious	1	deleterious	0,77	low_impact	-2,35	medium_impact	0,31	medium_impact	0,82	0,48	0,8	50,44	8,5	N	0,31	N	0,79	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6132	6132	G	T	MI.2372	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	229	77	G	C	Ggc/Tgc	-4,73	0	0	probably_damaging	1	deleterious	0	neutral	2,07	deleterious	-6,1	deleterious	-6,01	high_impact	5,17	damaging	0,48	damaging	0,14	deleterious	4,09	23,7	0,15	0,55	disease	0,86	disease	0,91	disease	0,65	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,55	0,9	2,14	6,61	P	0,56	P	0,98	disease_causing	0,8	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14450	14450	A	C	MI.23720	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	224	75	I	S	aTt/aGt	-6,7	0	0	probably_damaging	0,96	neutral	0,8	neutral	2,42	neutral	1,9	neutral	0,41	neutral_impact	0,78	neutral	0,88	neutral	0,91	deleterious	3,94	23,5	0,43	0,55	neutral	0,25	disease	0,72	neutral	0,17	disease	0,51	0	neutral	0,95	neutral	0,42	neutral	-2	deleterious	0,69	low_impact	-2,06	medium_impact	0,54	medium_impact	-0,49	0,4	0,8	50,44	8,5	N	0,34	N	0,67	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14450	14450	A	G	MI.23721	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	224	75	I	T	aTt/aCt	-6,7	0	0	possibly_damaging	0,89	neutral	0,64	neutral	2,34	neutral	0,58	neutral	2,96	neutral_impact	-0,24	neutral	0,9	neutral	0,91	deleterious	0,87	9,91	0,38	0,5	neutral	0,09	neutral	0,39	neutral	0,12	neutral	0,41	2	neutral	0,87	neutral	0,38	neutral	-3	deleterious	0,59	low_impact	-1,63	medium_impact	0,35	low_impact	-1,34	0,39	0,8	50,44	8,5	N	0,34	N	0,23	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14451	14451	T	A	MI.23722	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	223	75	I	F	Att/Ttt	0,18	0	0	probably_damaging	0,96	neutral	0,42	neutral	2,3	neutral	-1,4	neutral	-1,37	medium_impact	2	neutral	0,68	neutral	0,56	deleterious	4,33	24	0,45	0,55	neutral	0,37	disease	0,78	neutral	0,37	disease	0,64	3	neutral	0,96	neutral	0,23	deleterious	1	deleterious	0,73	low_impact	-2,06	medium_impact	0,13	medium_impact	0,54	0,54	0,8	50,44	8,5	N	0,32	N	0,66	NA	NA	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14451	14451	T	C	MI.23723	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	223	75	I	V	Att/Gtt	0,18	0	0	benign	0,15	neutral	0,47	neutral	2,32	neutral	-0,11	neutral	0,54	low_impact	1,45	neutral	0,66	neutral	0,67	deleterious	1,82	15,08	0,53	0,6	neutral	0,15	neutral	0,42	neutral	0,37	neutral	0,41	2	neutral	0,44	deleterious	0,66	neutral	-6	neutral	0,17	medium_impact	-0,11	medium_impact	0,18	medium_impact	0,08	0,46	0,8	50,44	8,5	N	0,42	N	0,58	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14451	14451	T	G	MI.23724	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	223	75	I	L	Att/Ctt	0,18	0	0	possibly_damaging	0,67	neutral	0,58	neutral	2,33	neutral	0,11	neutral	-0,1	medium_impact	2	neutral	0,68	neutral	0,55	deleterious	4,04	23,7	0,42	0,5	neutral	0,19	disease	0,6	neutral	0,32	disease	0,51	0	neutral	0,62	neutral	0,46	NA	0	deleterious	0,49	low_impact	-1,08	medium_impact	0,28	medium_impact	0,54	0,55	0,8	50,44	8,5	N	0,32	N	0,64	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14453	14453	G	C	MI.23725	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	221	74	A	G	gCt/gGt	-4,17	0	0	probably_damaging	1	neutral	0,4	neutral	2,22	deleterious	-3,43	deleterious	-3,79	high_impact	3,92	neutral	0,66	damaging	0,13	deleterious	3,6	23,2	0,29	0,45	disease	0,52	disease	0,87	disease	0,72	disease	0,79	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-3,55	medium_impact	0,11	high_impact	2,14	0,81	0,85	16,81	15,96	N	0,31	N	0,8	NA	NA	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14453	14453	G	A	MI.23726	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	221	74	A	V	gCt/gTt	-4,17	0	0	probably_damaging	1	neutral	0,56	neutral	2,3	neutral	-2,72	deleterious	-3,92	medium_impact	2,54	damaging	0,29	neutral	0,32	deleterious	4,14	23,8	0,48	0,55	disease	0,61	disease	0,87	disease	0,57	disease	0,56	1	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,85	low_impact	-3,55	medium_impact	0,27	medium_impact	0,99	0,86	0,9	16,81	15,96	P	0,81	P	0,81	NA	NA	0,6	rs199476107	Pathogenic	Juvenile_myopathy,_encephalopathy,_lactic_acidosis_AND_stroke	RCV000010331.4	MedGen:OMIM:Orphanet:SNOMED_CT	.	COSM1155561	CPD	0,15	G14453A	MELAS	-	+	Reported	4
chrM	14453	14453	G	T	MI.23727	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	221	74	A	D	gCt/gAt	-4,17	0	0	probably_damaging	1	neutral	0,37	neutral	2,2	deleterious	-4,36	deleterious	-5,65	high_impact	3,92	neutral	0,68	damaging	0,05	deleterious	3,98	23,6	0,26	0,45	disease	0,72	disease	0,95	disease	0,8	disease	0,91	8	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	0,08	high_impact	2,14	0,81	0,85	16,81	15,96	N	0,35	N	0,96	NA	NA	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14454	14454	C	T	MI.23728	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	220	74	A	T	Gct/Act	2,94	0,22	0	probably_damaging	1	neutral	0,51	neutral	2,34	neutral	-2,66	deleterious	-3,73	medium_impact	2,67	neutral	0,68	damaging	0,12	deleterious	4,39	24,1	0,54	0,6	neutral	0,49	disease	0,89	disease	0,64	disease	0,57	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,85	low_impact	-3,55	medium_impact	0,22	medium_impact	1,1	0,79	0,85	16,81	15,96	N	0,3	N	0,92	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14454	14454	C	G	MI.23729	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	220	74	A	P	Gct/Cct	2,94	0,22	0	probably_damaging	1	neutral	0,3	neutral	2,2	deleterious	-4,49	deleterious	-4,79	high_impact	3,57	neutral	0,72	damaging	0,07	deleterious	4,03	23,6	0,2	0,45	disease	0,7	disease	0,93	disease	0,82	disease	0,89	8	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0	medium_impact	1,85	0,82	0,85	16,81	15,96	N	0,51	P	0,97	NA	NA	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6133	6133	G	T	MI.2373	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	230	77	G	V	gGc/gTc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,1	deleterious	-4,57	deleterious	-6,01	high_impact	5,17	damaging	0,49	damaging	0,16	deleterious	3,64	23,2	0,13	0,55	disease	0,59	disease	0,92	disease	0,67	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,56	0,9	2,14	6,61	P	0,64	P	0,93	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14454	14454	C	A	MI.23730	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	220	74	A	S	Gct/Tct	2,94	0,22	0	probably_damaging	1	neutral	0,7	neutral	2,51	neutral	-1,36	deleterious	-2,6	medium_impact	2,44	neutral	0,77	neutral	0,73	deleterious	3,08	22,5	0,4	0,5	neutral	0,27	disease	0,88	disease	0,54	disease	0,56	1	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,81	low_impact	-3,55	medium_impact	0,41	medium_impact	0,9	0,9	0,95	16,81	15,96	N	0,3	N	0,93	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14455	14455	C	A	MI.23731	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	219	73	M	I	atG/atT	-0,27	0	0	probably_damaging	0,99	neutral	0,34	neutral	2,04	neutral	-0,5	deleterious	-3,84	medium_impact	3,23	neutral	0,63	damaging	0,07	deleterious	2,17	17,32	0,54	0,6	neutral	0,25	disease	0,87	disease	0,54	disease	0,78	6	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-2,63	medium_impact	0,05	medium_impact	1,57	0,77	0,85	25,22	18,16	N	0,31	N	0,79	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14455	14455	C	G	MI.23732	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	219	73	M	I	atG/atC	-0,27	0	0	probably_damaging	0,99	neutral	0,34	neutral	2,04	neutral	-0,5	deleterious	-3,84	medium_impact	3,23	neutral	0,63	damaging	0,07	deleterious	1,83	15,19	0,54	0,6	neutral	0,25	disease	0,87	disease	0,54	disease	0,78	6	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-2,63	medium_impact	0,05	medium_impact	1,57	0,77	0,85	25,22	18,16	N	0,31	N	0,79	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14456	14456	A	G	MI.23733	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	218	73	M	T	aTg/aCg	-6,01	0	0	probably_damaging	0,99	neutral	0,33	neutral	1,98	deleterious	-3,1	deleterious	-5,88	high_impact	3,58	neutral	0,66	damaging	0,1	neutral	1,49	13,28	0,44	0,55	neutral	0,4	disease	0,87	disease	0,66	disease	0,79	6	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-2,63	medium_impact	0,04	medium_impact	1,86	0,49	0,8	25,22	18,16	N	0,31	N	0,88	NA	NA	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14456	14456	A	T	MI.23734	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	218	73	M	K	aTg/aAg	-6,01	0	0	probably_damaging	0,99	neutral	0,28	neutral	1,92	deleterious	-4,2	deleterious	-5,91	high_impact	3,58	neutral	0,62	damaging	0,06	deleterious	3,5	23,1	0,22	0,45	neutral	0,44	disease	0,93	disease	0,73	disease	0,83	7	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,87	low_impact	-2,63	medium_impact	-0,02	medium_impact	1,86	0,56	0,8	25,22	18,16	N	0,32	N	0,93	NA	NA	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14457	14457	T	A	MI.23735	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	217	73	M	L	Atg/Ttg	3,17	0,03	0	probably_damaging	0,98	neutral	1	neutral	2,42	neutral	1,61	deleterious	-2,82	neutral_impact	0,75	neutral	0,84	neutral	0,51	deleterious	0,77	9,25	0,45	0,55	neutral	0,09	neutral	0,4	neutral	0,25	neutral	0,41	2	neutral	0,98	deleterious	0,51	neutral	-2	deleterious	0,65	low_impact	-2,35	high_impact	1,87	medium_impact	-0,51	0,65	0,8	25,22	18,16	N	0,29	N	0,36	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14457	14457	T	C	MI.23736	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	217	73	M	V	Atg/Gtg	3,17	0,03	0	probably_damaging	0,99	neutral	0,4	neutral	2,03	neutral	-1,15	deleterious	-3,88	medium_impact	3,23	neutral	0,78	damaging	0,12	deleterious	0,77	9,29	0,52	0,6	neutral	0,25	disease	0,87	disease	0,56	disease	0,78	6	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,78	low_impact	-2,63	medium_impact	0,11	medium_impact	1,57	0,66	0,8	25,22	18,16	N	0,28	N	0,74	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14457	14457	T	G	MI.23737	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	217	73	M	L	Atg/Ctg	3,17	0,03	0	probably_damaging	0,98	neutral	1	neutral	2,42	neutral	1,61	deleterious	-2,82	neutral_impact	0,75	neutral	0,84	neutral	0,51	deleterious	0,64	8,4	0,45	0,55	neutral	0,09	neutral	0,4	neutral	0,25	neutral	0,41	2	neutral	0,98	deleterious	0,51	neutral	-2	deleterious	0,65	low_impact	-2,35	high_impact	1,87	medium_impact	-0,51	0,65	0,8	25,22	18,16	N	0,29	N	0,36	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14459	14459	G	A	MI.23738	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	215	72	A	V	gCg/gTg	-3,71	0	0	probably_damaging	1	neutral	0,3	neutral	2,27	neutral	-0,53	deleterious	-3,98	high_impact	3,61	damaging	0,08	damaging	0,15	deleterious	4,08	23,7	0,4	0,5	disease	0,61	disease	0,92	disease	0,79	disease	0,84	7	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,87	low_impact	-3,55	medium_impact	0	medium_impact	1,88	0,86	0,9	27,88	11,58	P	0,93	P	0,81	NA	NA	0,61	rs199476105	Pathogenic|Pathogenic|Pathogenic|Pathogenic	Leber_hereditary_optic_neuropathy_with_dystonia|Leber's_optic_atrophy|Leigh_syndrome_due_to_mitochondrial_complex_I_deficiency|Leigh_syndrome	RCV000010326.2|RCV000010327.2|RCV000010328.4|RCV000144019.2	MedGen:OMIM|MedGen:OMIM:SNOMED_CT|MedGen|MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	G14459A	LDYT/Leigh Disease	+	+	Cfrm	24
chrM	14459	14459	G	T	MI.23739	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	215	72	A	E	gCg/gAg	-3,71	0	0	probably_damaging	1	neutral	0,25	neutral	2,16	deleterious	-3,61	deleterious	-4,98	high_impact	3,96	damaging	0,35	damaging	0,19	deleterious	3,88	23,5	0,15	0,4	disease	0,7	disease	0,95	disease	0,82	disease	0,92	8	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,06	high_impact	2,18	0,8	0,85	27,88	11,58	P	0,63	P	0,99	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6133	6133	G	C	MI.2374	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	230	77	G	A	gGc/gCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,53	neutral	-1,25	deleterious	-4	medium_impact	3,33	neutral	0,66	neutral	0,3	deleterious	2,98	22,2	0,25	0,55	neutral	0,36	disease	0,79	disease	0,56	disease	0,64	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	medium_impact	1,98	0,71	0,9	2,14	6,61	N	0,47	N	0,64	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14459	14459	G	C	MI.23740	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	215	72	A	G	gCg/gGg	-3,71	0	0	probably_damaging	1	neutral	0,2	neutral	2,17	neutral	-2,95	deleterious	-3,98	high_impact	3,96	damaging	0,46	neutral	0,46	deleterious	3,56	23,1	0,25	0,45	disease	0,53	disease	0,91	disease	0,78	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,55	medium_impact	-0,13	high_impact	2,18	0,81	0,85	27,88	11,58	N	0,55	P	0,8	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14460	14460	C	G	MI.23741	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	214	72	A	P	Gcg/Ccg	4,31	0,98	0	probably_damaging	1	neutral	0,22	neutral	2,16	deleterious	-4,01	deleterious	-4,98	high_impact	3,96	damaging	0,4	damaging	0,21	deleterious	4,05	23,7	0,2	0,45	disease	0,7	disease	0,95	disease	0,86	disease	0,94	9	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,1	high_impact	2,18	0,77	0,85	27,88	11,58	P	0,81	P	0,97	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14460	14460	C	A	MI.23742	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	214	72	A	S	Gcg/Tcg	4,31	0,98	0	probably_damaging	1	neutral	0,7	neutral	2,39	neutral	0,51	deleterious	-2,99	medium_impact	2,35	neutral	0,61	neutral	0,67	deleterious	4,04	23,7	0,33	0,5	neutral	0,3	disease	0,68	disease	0,6	disease	0,51	0	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,79	low_impact	-3,55	medium_impact	0,41	medium_impact	0,83	0,85	0,9	27,88	11,58	N	0,53	P	0,93	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14460	14460	C	T	MI.23743	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	214	72	A	T	Gcg/Acg	4,31	0,98	0	probably_damaging	1	neutral	0,37	neutral	2,23	neutral	-1,16	deleterious	-3,98	high_impact	3,96	damaging	0,38	damaging	0,23	deleterious	4,37	24,1	0,38	0,5	neutral	0,5	disease	0,92	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	0,08	high_impact	2,18	0,86	0,9	27,88	11,58	P	0,84	P	0,92	NA	NA	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14462	14462	G	T	MI.23744	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	212	71	T	K	aCa/aAa	-12,43	0	0	possibly_damaging	0,58	neutral	0,27	neutral	2,21	deleterious	-3,01	deleterious	-5,29	medium_impact	3,33	neutral	0,69	neutral	0,33	deleterious	3,66	23,2	0,16	0,45	neutral	0,46	disease	0,87	disease	0,73	disease	0,82	6	neutral	0,73	neutral	0,35	NA	0	deleterious	0,68	medium_impact	-0,92	medium_impact	-0,03	medium_impact	1,65	0,87	0,9	44,25	8,42	N	0,37	N	0,94	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14462	14462	G	A	MI.23745	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	212	71	T	M	aCa/aTa	-12,43	0	0	benign	0,26	neutral	0,21	neutral	2,24	neutral	-1,45	deleterious	-5,17	medium_impact	3,33	neutral	0,66	neutral	0,38	deleterious	1,85	15,3	0,26	0,45	disease	0,61	disease	0,73	disease	0,67	disease	0,75	5	neutral	0,75	deleterious	0,48	neutral	-3	neutral	0,42	medium_impact	-0,38	medium_impact	-0,11	medium_impact	1,65	0,86	0,9	44,25	8,42	N	0,38	N	0,9	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14463	14463	T	G	MI.23746	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	211	71	T	P	Aca/Cca	2,02	0,06	0	possibly_damaging	0,82	neutral	0,16	neutral	2,21	deleterious	-3,05	deleterious	-5,29	medium_impact	3,33	neutral	0,7	neutral	0,28	deleterious	3,63	23,2	0,15	0,4	disease	0,58	disease	0,91	disease	0,73	disease	0,84	7	neutral	0,91	neutral	0,17	NA	0	deleterious	0,82	low_impact	-1,4	medium_impact	-0,19	medium_impact	1,65	0,77	0,85	44,25	8,42	N	0,45	N	0,94	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14463	14463	T	C	MI.23747	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	211	71	T	A	Aca/Gca	2,02	0,06	0	benign	0,02	neutral	1	neutral	2,3	neutral	-0,24	deleterious	-3,79	neutral_impact	0,23	neutral	0,91	neutral	0,93	deleterious	-0,05	2,09	0,32	0,5	neutral	0,15	neutral	0,18	neutral	0,25	neutral	0,28	4	neutral	0,01	deleterious	0,99	neutral	-6	neutral	0,13	medium_impact	0,75	high_impact	1,87	medium_impact	-0,95	0,62	0,8	44,25	8,42	N	0,43	N	0,65	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14463	14463	T	A	MI.23748	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	211	71	T	S	Aca/Tca	2,02	0,06	0	benign	0,37	neutral	0,77	neutral	2,35	neutral	0,28	deleterious	-3,32	medium_impact	2,23	neutral	0,81	neutral	0,72	deleterious	1,9	15,57	0,37	0,5	neutral	0,2	disease	0,64	neutral	0,33	neutral	0,48	0	neutral	0,26	deleterious	0,7	neutral	-3	deleterious	0,45	medium_impact	-0,58	medium_impact	0,5	medium_impact	0,73	0,79	0,85	44,25	8,42	N	0,31	N	0,68	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14465	14465	G	C	MI.23749	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	209	70	T	S	aCt/aGt	-7,16	0	0	probably_damaging	1	neutral	0,76	neutral	2,36	neutral	0,4	deleterious	-3,99	low_impact	1,17	neutral	0,72	neutral	0,31	deleterious	3,11	22,5	0,48	0,55	neutral	0,11	neutral	0,17	neutral	0,26	neutral	0,24	5	deleterious	1	neutral	0,38	neutral	-2	deleterious	0,65	low_impact	-3,55	medium_impact	0,48	medium_impact	-0,16	0,89	0,9	49,12	8,68	N	0,3	N	0,87	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6133	6133	G	A	MI.2375	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	230	77	G	D	gGc/gAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,05	deleterious	-7,57	deleterious	-4,67	high_impact	5,17	damaging	0,45	damaging	0,14	deleterious	3,73	23,3	0,14	0,55	disease	0,83	disease	0,89	disease	0,75	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,45	0,9	2,14	6,61	P	0,68	P	0,97	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14465	14465	G	A	MI.23750	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	209	70	T	I	aCt/aTt	-7,16	0	0	probably_damaging	1	neutral	0,42	neutral	2,4	neutral	0,81	deleterious	-5,98	high_impact	3,63	neutral	0,61	damaging	0,03	deleterious	3,53	23,1	0,37	0,5	disease	0,63	disease	0,91	disease	0,66	disease	0,8	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	0,13	medium_impact	1,9	0,84	0,9	49,12	8,68	N	0,28	N	0,93	NA	NA	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14465	14465	G	T	MI.23751	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	209	70	T	N	aCt/aAt	-7,16	0	0	probably_damaging	1	neutral	0,3	neutral	2,22	deleterious	-3,09	deleterious	-4,99	high_impact	3,63	neutral	0,61	damaging	0,03	deleterious	3,1	22,5	0,31	0,5	disease	0,54	disease	0,91	disease	0,65	disease	0,79	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,55	medium_impact	0	medium_impact	1,9	0,87	0,9	49,12	8,68	N	0,27	N	0,93	NA	NA	0,76	.	.	.	.	.	.	COSM1138266	.	.	.	.	.	.	.	.
chrM	14466	14466	T	C	MI.23752	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	208	70	T	A	Act/Gct	4,08	1	0	probably_damaging	1	neutral	0,58	neutral	2,32	neutral	-0,04	deleterious	-4,98	medium_impact	2,83	neutral	0,64	damaging	0,14	deleterious	3,33	22,9	0,55	0,6	neutral	0,29	disease	0,79	disease	0,53	disease	0,68	4	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,76	low_impact	-3,55	medium_impact	0,28	medium_impact	1,23	0,79	0,85	49,12	8,68	N	0,48	N	0,68	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14466	14466	T	G	MI.23753	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	208	70	T	P	Act/Cct	4,08	1	0	probably_damaging	1	neutral	0,19	neutral	2,22	deleterious	-3,39	deleterious	-5,98	high_impact	3,63	neutral	0,67	damaging	0,03	deleterious	3,67	23,3	0,16	0,45	disease	0,61	disease	0,95	disease	0,75	disease	0,91	8	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,14	medium_impact	1,9	0,76	0,85	49,12	8,68	P	0,61	P	0,97	NA	NA	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14466	14466	T	A	MI.23754	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	208	70	T	S	Act/Tct	4,08	1	0	probably_damaging	1	neutral	0,76	neutral	2,36	neutral	0,4	deleterious	-3,99	low_impact	1,17	neutral	0,72	neutral	0,31	deleterious	3,7	23,3	0,48	0,55	neutral	0,11	neutral	0,17	neutral	0,26	neutral	0,24	5	deleterious	1	neutral	0,38	neutral	-2	deleterious	0,65	low_impact	-3,55	medium_impact	0,48	medium_impact	-0,16	0,89	0,9	49,12	8,68	N	0,42	N	0,87	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14468	14468	T	A	MI.23755	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	206	69	Y	F	tAt/tTt	2,48	1	0	probably_damaging	1	neutral	0,51	neutral	2,55	neutral	0,56	deleterious	-3,99	medium_impact	3,46	damaging	0,47	damaging	0,13	deleterious	3,6	23,2	0,29	0,45	neutral	0,45	disease	0,94	disease	0,73	disease	0,85	7	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,86	low_impact	-3,55	medium_impact	0,22	medium_impact	1,76	0,7	0,85	12,39	14,86	N	0,48	N	0,8	NA	NA	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14468	14468	T	G	MI.23756	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	206	69	Y	S	tAt/tCt	2,48	1	0	probably_damaging	1	neutral	0,4	neutral	1,65	deleterious	-6,99	deleterious	-8,97	high_impact	3,66	damaging	0,41	damaging	0,06	deleterious	3,88	23,5	0,2	0,45	disease	0,81	disease	0,95	disease	0,78	disease	0,9	8	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0,11	medium_impact	1,93	0,52	0,8	12,39	14,86	P	0,71	P	0,96	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14468	14468	T	C	MI.23757	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	206	69	Y	C	tAt/tGt	2,48	1	0	probably_damaging	1	neutral	0,13	neutral	1,65	deleterious	-8,26	deleterious	-8,96	high_impact	4	damaging	0,4	damaging	0,04	deleterious	3,25	22,8	0,27	0,45	disease	0,92	disease	0,96	disease	0,83	disease	0,91	8	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,91	low_impact	-3,55	medium_impact	-0,25	high_impact	2,21	0,39	0,8	12,39	14,86	P	0,73	P	1	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14469	14469	A	G	MI.23758	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	205	69	Y	H	Tat/Cat	3,63	1	0	probably_damaging	1	neutral	0,33	neutral	1,66	deleterious	-6,32	deleterious	-4,98	medium_impact	3,46	damaging	0,57	damaging	0,05	deleterious	3,58	23,2	0,24	0,45	disease	0,76	disease	0,93	disease	0,83	disease	0,91	8	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,89	low_impact	-3,55	medium_impact	0,04	medium_impact	1,76	0,58	0,8	12,39	14,86	N	0,45	N	0,98	NA	NA	0,85	.	.	.	.	.	.	COSM1138268	.	.	.	.	.	.	.	.
chrM	14469	14469	A	C	MI.23759	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	205	69	Y	D	Tat/Gat	3,63	1	0	probably_damaging	1	neutral	0,12	neutral	1,65	deleterious	-8,57	deleterious	-9,96	high_impact	4	damaging	0,39	damaging	0,03	deleterious	3,54	23,1	0,13	0,4	disease	0,87	disease	0,96	disease	0,85	disease	0,91	8	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,27	high_impact	2,21	0,43	0,8	12,39	14,86	P	0,72	P	0,97	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6135	6135	T	A	MI.2376	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	232	78	F	I	Ttt/Att	-15,37	0	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-2,52	deleterious	-4	high_impact	4,07	damaging	0,58	neutral	0,64	deleterious	4,17	23,8	0,29	0,55	neutral	0,44	disease	0,91	disease	0,69	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,66	0,61	0,9	1,56	8,79	N	0,44	N	0,88	polymorphism	0,68	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14469	14469	A	T	MI.23760	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	205	69	Y	N	Tat/Aat	3,63	1	0	probably_damaging	1	neutral	0,24	neutral	1,65	deleterious	-7,44	deleterious	-8,97	high_impact	4	damaging	0,31	damaging	0,05	deleterious	3,52	23,1	0,2	0,45	disease	0,84	disease	0,95	disease	0,8	disease	0,91	8	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,07	high_impact	2,21	0,5	0,8	12,39	14,86	P	0,6	P	1	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14471	14471	C	G	MI.23761	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	203	68	G	A	gGa/gCa	-4,17	0	0	probably_damaging	1	neutral	0,6	neutral	2,42	neutral	1,74	deleterious	-5,6	low_impact	1,18	neutral	0,78	neutral	0,61	neutral	1,49	13,26	0,34	0,5	neutral	0,15	neutral	0,29	neutral	0,2	neutral	0,43	1	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,67	low_impact	-3,55	medium_impact	0,3	medium_impact	-0,15	0,9	0,95	49,56	8,58	N	0,3	N	0,78	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14471	14471	C	A	MI.23762	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	203	68	G	V	gGa/gTa	-4,17	0	0	probably_damaging	1	neutral	0,56	neutral	2,43	neutral	1,87	deleterious	-8,63	medium_impact	2,15	neutral	0,65	damaging	0,27	deleterious	4,2	23,9	0,18	0,45	neutral	0,19	disease	0,84	neutral	0,38	disease	0,6	2	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	0,27	medium_impact	0,66	0,84	0,9	49,56	8,58	N	0,32	N	0,98	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14471	14471	C	T	MI.23763	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	203	68	G	E	gGa/gAa	-4,17	0	0	probably_damaging	1	neutral	0,26	neutral	2,29	neutral	-1,62	deleterious	-7,71	high_impact	3,62	neutral	0,63	damaging	0,06	deleterious	4,01	23,6	0,1	0,4	neutral	0,41	disease	0,93	disease	0,7	disease	0,81	6	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,84	low_impact	-3,55	medium_impact	-0,05	medium_impact	1,89	0,84	0,9	49,56	8,58	N	0,35	N	1	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14472	14472	C	G	MI.23764	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	202	68	G	R	Gga/Cga	1,79	0,96	0	probably_damaging	1	neutral	0,32	neutral	2,3	neutral	-1,34	deleterious	-7,71	high_impact	3,62	neutral	0,62	damaging	0,04	deleterious	4,09	23,7	0,09	0,35	neutral	0,46	disease	0,95	disease	0,72	disease	0,89	8	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	0,03	medium_impact	1,89	0,74	0,85	49,56	8,58	N	0,46	N	1	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14472	14472	C	A	MI.23765	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	202	68	G	W	Gga/Tga	1,79	0,96	0	probably_damaging	1	neutral	0,17	neutral	2,29	neutral	-2,61	deleterious	-7,78	high_impact	3,62	neutral	0,63	damaging	0,06	deleterious	4,75	24,7	0,11	0,4	disease	0,79	disease	0,94	disease	0,66	disease	0,85	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,18	medium_impact	1,89	0,63	0,8	49,56	8,58	N	0,45	N	1	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14473	14473	A	C	MI.23766	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	201	67	F	L	ttT/ttG	5,23	1	0	probably_damaging	1	neutral	0,18	neutral	1,55	deleterious	-3,86	deleterious	-5,98	high_impact	4,01	damaging	0,51	damaging	0,03	deleterious	3,99	23,6	0,19	0,45	disease	0,54	disease	0,95	disease	0,72	disease	0,86	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	-0,16	high_impact	2,22	0,7	0,85	13,27	10,97	P	0,59	P	0,9	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14473	14473	A	T	MI.23767	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	201	67	F	L	ttT/ttA	5,23	1	0	probably_damaging	1	neutral	0,18	neutral	1,55	deleterious	-3,86	deleterious	-5,98	high_impact	4,01	damaging	0,51	damaging	0,03	deleterious	4,12	23,8	0,19	0,45	disease	0,54	disease	0,95	disease	0,72	disease	0,86	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	-0,16	high_impact	2,22	0,7	0,85	13,27	10,97	P	0,63	P	0,9	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14474	14474	A	T	MI.23768	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	200	67	F	Y	tTt/tAt	4,54	1	0	probably_damaging	1	neutral	0,4	neutral	1,45	neutral	-2,53	deleterious	-2,99	high_impact	4,01	damaging	0,51	damaging	0,04	deleterious	3,85	23,4	0,14	0,4	neutral	0,48	disease	0,94	disease	0,74	disease	0,88	8	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	0,11	high_impact	2,22	0,65	0,8	13,27	10,97	P	0,64	P	0,88	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14474	14474	A	C	MI.23769	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	200	67	F	C	tTt/tGt	4,54	1	0	probably_damaging	1	neutral	0,08	neutral	1,41	deleterious	-7,38	deleterious	-7,98	high_impact	4,01	damaging	0,53	damaging	0,03	deleterious	3,65	23,2	0,13	0,4	disease	0,91	disease	0,96	disease	0,77	disease	0,89	8	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,38	high_impact	2,22	0,39	0,8	13,27	10,97	P	0,62	P	0,98	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6135	6135	T	G	MI.2377	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	232	78	F	V	Ttt/Gtt	-15,37	0	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-2,52	deleterious	-4,67	high_impact	4,47	damaging	0,54	neutral	0,5	deleterious	3,94	23,5	0,32	0,55	disease	0,51	disease	0,92	disease	0,73	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,03	0,56	0,9	1,56	8,79	N	0,53	P	0,84	polymorphism	0,5	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14474	14474	A	G	MI.23770	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	200	67	F	S	tTt/tCt	4,54	1	0	probably_damaging	1	neutral	0,1	neutral	1,43	deleterious	-5,81	deleterious	-7,98	high_impact	4,01	damaging	0,55	damaging	0,04	deleterious	4,27	23,9	0,09	0,35	disease	0,81	disease	0,96	disease	0,73	disease	0,87	7	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,32	high_impact	2,22	0,53	0,8	13,27	10,97	P	0,58	P	0,97	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14475	14475	A	T	MI.23771	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	199	67	F	I	Ttt/Att	6,61	1	0	probably_damaging	1	neutral	0,35	neutral	1,54	deleterious	-4,97	deleterious	-5,98	high_impact	4,01	damaging	0,52	damaging	0,04	deleterious	3,89	23,5	0,15	0,4	disease	0,7	disease	0,96	disease	0,75	disease	0,88	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	0,06	high_impact	2,22	0,59	0,8	13,27	10,97	P	0,63	P	0,92	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14475	14475	A	C	MI.23772	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	199	67	F	V	Ttt/Gtt	6,61	1	0	probably_damaging	1	neutral	0,22	neutral	1,52	deleterious	-4,93	deleterious	-6,98	high_impact	3,66	damaging	0,47	damaging	0,03	deleterious	3,6	23,2	0,13	0,4	disease	0,71	disease	0,97	disease	0,75	disease	0,89	8	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,1	medium_impact	1,93	0,63	0,8	13,27	10,97	P	0,65	P	0,95	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14475	14475	A	G	MI.23773	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	199	67	F	L	Ttt/Ctt	6,61	1	0	probably_damaging	1	neutral	0,18	neutral	1,55	deleterious	-3,86	deleterious	-5,98	high_impact	4,01	damaging	0,51	damaging	0,03	deleterious	4,04	23,7	0,19	0,45	disease	0,54	disease	0,95	disease	0,72	disease	0,86	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	-0,16	high_impact	2,22	0,7	0,85	13,27	10,97	P	0,61	P	0,9	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14477	14477	A	C	MI.23774	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	197	66	V	G	gTc/gGc	-6,47	0	0	probably_damaging	1	neutral	0,05	neutral	2,13	deleterious	-5,14	deleterious	-6,98	high_impact	4	damaging	0,5	damaging	0,06	deleterious	3,36	22,9	0,14	0,4	disease	0,78	disease	0,93	disease	0,73	disease	0,83	7	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	-0,5	high_impact	2,21	0,64	0,8	18,14	13,71	N	0,3	N	0,83	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14477	14477	A	G	MI.23775	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	197	66	V	A	gTc/gCc	-6,47	0	0	probably_damaging	1	neutral	0,08	neutral	2,15	neutral	-2,75	deleterious	-3,99	high_impact	3,66	damaging	0,53	damaging	0,08	deleterious	3,5	23,1	0,3	0,45	disease	0,59	disease	0,84	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,8	low_impact	-3,55	medium_impact	-0,38	medium_impact	1,93	0,6	0,8	18,14	13,71	N	0,28	N	0,52	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14477	14477	A	T	MI.23776	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	197	66	V	D	gTc/gAc	-6,47	0	0	probably_damaging	1	deleterious	0,01	neutral	2,12	deleterious	-6,17	deleterious	-6,97	high_impact	4	damaging	0,57	damaging	0,04	deleterious	3,9	23,5	0,1	0,4	disease	0,87	disease	0,96	disease	0,8	disease	0,91	8	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,55	medium_impact	-0,9	high_impact	2,21	0,71	0,85	18,14	13,71	N	0,33	N	0,94	NA	NA	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14478	14478	C	T	MI.23777	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	196	66	V	I	Gtc/Atc	5,46	0,99	0	probably_damaging	1	neutral	0,31	neutral	2,29	neutral	-0,29	neutral	-1	medium_impact	3,31	neutral	0,64	damaging	0,09	deleterious	3,86	23,5	0,42	0,5	neutral	0,34	disease	0,81	disease	0,66	disease	0,58	2	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,76	low_impact	-3,55	medium_impact	0,01	medium_impact	1,63	0,88	0,9	18,14	13,71	N	0,47	N	0,46	NA	NA	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14478	14478	C	A	MI.23778	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	196	66	V	F	Gtc/Ttc	5,46	0,99	0	probably_damaging	1	neutral	0,42	neutral	2,19	neutral	-1,57	deleterious	-4,99	high_impact	4	damaging	0,58	damaging	0,03	deleterious	4,15	23,8	0,16	0,45	disease	0,74	disease	0,96	disease	0,76	disease	0,88	8	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-3,55	medium_impact	0,13	high_impact	2,21	0,77	0,85	18,14	13,71	P	0,54	P	0,93	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14478	14478	C	G	MI.23779	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	196	66	V	L	Gtc/Ctc	5,46	0,99	0	probably_damaging	1	neutral	0,42	neutral	3,21	neutral	2,91	deleterious	-2,99	high_impact	4	damaging	0,49	damaging	0,04	deleterious	3,69	23,3	0,39	0,5	neutral	0,45	disease	0,92	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,82	low_impact	-3,55	medium_impact	0,13	high_impact	2,21	0,8	0,85	18,14	13,71	P	0,59	P	0,79	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6135	6135	T	C	MI.2378	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	232	78	F	L	Ttt/Ctt	-15,37	0	0	probably_damaging	1	deleterious	0	neutral	2,84	neutral	-1,32	deleterious	-4	high_impact	3,64	damaging	0,54	neutral	0,61	deleterious	3,61	23,2	0,42	0,55	neutral	0,29	disease	0,82	disease	0,67	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	high_impact	2,26	0,57	0,9	1,56	8,79	N	0,41	N	0,83	polymorphism	0,66	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14480	14480	A	T	MI.23780	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	194	65	V	D	gTt/gAt	-10,37	0	0	probably_damaging	0,98	deleterious	0,01	neutral	1,68	deleterious	-8,11	deleterious	-6,97	high_impact	3,91	damaging	0,51	neutral	0,38	deleterious	4,53	24,3	0,1	0,4	disease	0,87	disease	0,95	disease	0,77	disease	0,9	8	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,87	low_impact	-2,35	medium_impact	-0,9	high_impact	2,14	0,63	0,8	49,12	8,59	N	0,44	N	0,94	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14480	14480	A	G	MI.23781	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	194	65	V	A	gTt/gCt	-10,37	0	0	possibly_damaging	0,82	neutral	0,1	neutral	1,73	deleterious	-4,08	deleterious	-3,99	high_impact	3,91	damaging	0,56	neutral	0,46	deleterious	3,87	23,5	0,22	0,45	disease	0,59	disease	0,83	disease	0,65	disease	0,71	4	neutral	0,94	neutral	0,14	deleterious	1	deleterious	0,74	low_impact	-1,4	medium_impact	-0,32	high_impact	2,14	0,52	0,8	49,12	8,59	N	0,44	N	0,52	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14480	14480	A	C	MI.23782	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	194	65	V	G	gTt/gGt	-10,37	0	0	probably_damaging	0,98	neutral	0,1	neutral	1,68	deleterious	-7,25	deleterious	-6,97	high_impact	3,91	damaging	0,52	neutral	0,43	deleterious	3,84	23,4	0,14	0,4	disease	0,78	disease	0,93	disease	0,67	disease	0,75	5	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-2,35	medium_impact	-0,32	high_impact	2,14	0,57	0,8	49,12	8,59	N	0,39	N	0,83	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14481	14481	C	G	MI.23783	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	193	65	V	L	Gtt/Ctt	8,44	1	0	possibly_damaging	0,62	neutral	0,56	neutral	1,76	deleterious	-3,36	deleterious	-2,99	high_impact	3,91	damaging	0,53	neutral	0,43	deleterious	2,12	17	0,2	0,45	neutral	0,45	disease	0,91	disease	0,64	disease	0,74	5	neutral	0,57	deleterious	0,47	deleterious	1	deleterious	0,65	medium_impact	-0,99	medium_impact	0,27	high_impact	2,14	0,7	0,85	49,12	8,59	P	0,66	P	0,79	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14481	14481	C	T	MI.23784	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	193	65	V	I	Gtt/Att	8,44	1	0	benign	0,18	neutral	0,26	neutral	2,4	neutral	0,19	neutral	-1	medium_impact	2,81	neutral	0,75	neutral	0,51	deleterious	1,91	15,67	0,3	0,45	neutral	0,34	disease	0,83	disease	0,6	disease	0,71	4	neutral	0,69	deleterious	0,54	neutral	-3	neutral	0,29	medium_impact	-0,19	medium_impact	-0,05	medium_impact	1,21	0,87	0,9	49,12	8,59	P	0,66	P	0,46	NA	NA	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14481	14481	C	A	MI.23785	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	193	65	V	F	Gtt/Ttt	8,44	1	0	probably_damaging	0,96	neutral	0,52	neutral	1,69	deleterious	-5,95	deleterious	-4,98	high_impact	3,91	damaging	0,52	neutral	0,35	deleterious	4,26	23,9	0,13	0,4	disease	0,74	disease	0,96	disease	0,71	disease	0,84	7	neutral	0,96	neutral	0,28	deleterious	2	deleterious	0,85	low_impact	-2,06	medium_impact	0,23	high_impact	2,14	0,68	0,85	49,12	8,59	P	0,65	P	0,93	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14482	14482	C	A	MI.23786	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	192	64	M	I	atG/atT	3,4	0,99	0	probably_damaging	0,99	neutral	0,31	neutral	2,16	neutral	-1,75	neutral	-1,3	medium_impact	3,06	damaging	0,19	damaging	0,25	deleterious	2,63	20,4	0,39	0,5	neutral	0,19	disease	0,9	disease	0,61	disease	0,8	6	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,79	low_impact	-2,63	medium_impact	0,01	medium_impact	1,42	0,78	0,85	18,14	20,1	P	0,96	P	0,87	NA	NA	0,33	rs199476108	Pathogenic,Pathogenic	Leber's_optic_atrophy,Leber's_optic_atrophy	RCV000010332.2,RCV000055701.1	MedGen:OMIM:SNOMED_CT,MedGen:OMIM:SNOMED_CT	.	.	.	.	C14482A	LHON	+	+	Cfrm	11
chrM	14482	14482	C	G	MI.23787	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	192	64	M	I	atG/atC	3,4	0,99	0	probably_damaging	0,99	neutral	0,31	neutral	2,16	neutral	-1,75	neutral	-1,3	medium_impact	3,06	damaging	0,19	damaging	0,25	deleterious	2,13	17,02	0,39	0,5	neutral	0,19	disease	0,9	disease	0,61	disease	0,8	6	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,79	low_impact	-2,63	medium_impact	0,01	medium_impact	1,42	0,78	0,85	18,14	20,1	P	0,96	P	0,87	NA	NA	0,33	rs199476108	Pathogenic,Pathogenic	Leber's_optic_atrophy,Leber's_optic_atrophy	RCV000010332.2,RCV000055701.1	MedGen:OMIM:SNOMED_CT,MedGen:OMIM:SNOMED_CT	.	.	.	.	C14482G	LHON	+	+	Cfrm	5
chrM	14483	14483	A	T	MI.23788	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	191	64	M	K	aTg/aAg	-2,8	0	0	probably_damaging	0,99	neutral	0,05	neutral	2,11	deleterious	-3,82	deleterious	-4,64	medium_impact	3,06	damaging	0,42	neutral	0,34	deleterious	3,56	23,1	0,15	0,4	disease	0,67	disease	0,96	disease	0,68	disease	0,87	7	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,89	low_impact	-2,63	medium_impact	-0,5	medium_impact	1,42	0,48	0,8	18,14	20,1	N	0,48	N	0,93	NA	NA	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14483	14483	A	G	MI.23789	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	191	64	M	T	aTg/aCg	-2,8	0	0	probably_damaging	0,99	deleterious	0,03	neutral	2,14	neutral	-2,27	deleterious	-3,96	medium_impact	3,06	damaging	0,41	neutral	0,45	deleterious	2,77	21,2	0,3	0,45	disease	0,5	disease	0,87	disease	0,62	disease	0,8	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,85	low_impact	-2,63	medium_impact	-0,63	medium_impact	1,42	0,39	0,8	18,14	20,1	P	0,53	P	0,78	NA	NA	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6136	6136	T	G	MI.2379	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	233	78	F	C	tTt/tGt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-5,75	deleterious	-5,34	high_impact	5,17	damaging	0,59	neutral	0,5	deleterious	3,95	23,6	0,26	0,55	disease	0,85	disease	0,88	disease	0,75	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,37	0,9	1,56	8,79	P	0,67	P	0,91	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14484	14484	T	C	MI.23790	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	190	64	M	V	Atg/Gtg	5,46	0,51	0,04	probably_damaging	0,99	neutral	0,49	neutral	2,26	neutral	-0,49	neutral	-1,97	medium_impact	3,06	damaging	0,24	neutral	0,47	neutral	0,89	10,02	0,39	0,5	neutral	0,23	disease	0,92	disease	0,61	disease	0,81	6	deleterious	0,99	neutral	0,25	deleterious	1	deleterious	0,8	low_impact	-2,63	medium_impact	0,2	medium_impact	1,42	0,58	0,8	18,14	20,1	P	0,95	P	0,71	NA	NA	0,39	rs199476104	Pathogenic|Pathogenic|Likely pathogenic	Leber's_optic_atrophy|Leigh_syndrome|not_provided	RCV000010325.5|RCV000144018.2|RCV000223709.1	MedGen:OMIM:SNOMED_CT|MedGen:OMIM:Orphanet:SNOMED_CT|MedGen	.	.	CPD	0,15	T14484C	LHON	+	+	Cfrm	142
chrM	14484	14484	T	A	MI.23791	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	190	64	M	L	Atg/Ttg	5,46	0,51	0,04	probably_damaging	0,98	neutral	1	neutral	2,42	neutral	0,6	neutral	0,36	neutral_impact	0	neutral	0,84	neutral	0,98	neutral	-0,99	0,02	0,33	0,5	neutral	0,17	disease	0,54	neutral	0,38	neutral	0,42	2	neutral	0,98	deleterious	0,51	neutral	-2	deleterious	0,66	low_impact	-2,35	high_impact	1,87	low_impact	-1,14	0,64	0,8	18,14	20,1	N	0,42	N	0,25	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14484	14484	T	G	MI.23792	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	190	64	M	L	Atg/Ctg	5,46	0,51	0,04	probably_damaging	0,98	neutral	1	neutral	2,42	neutral	0,6	neutral	0,36	neutral_impact	0	neutral	0,84	neutral	0,98	neutral	-1,1	0,01	0,33	0,5	neutral	0,17	disease	0,54	neutral	0,38	neutral	0,42	2	neutral	0,98	deleterious	0,51	neutral	-2	deleterious	0,66	low_impact	-2,35	high_impact	1,87	low_impact	-1,14	0,64	0,8	18,14	20,1	N	0,41	N	0,25	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14485	14485	C	A	MI.23793	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	189	63	M	I	atG/atT	-2,11	0	0	probably_damaging	0,99	neutral	0,31	neutral	2,72	deleterious	-3,54	deleterious	-3,99	high_impact	4,01	damaging	0,44	damaging	0,02	deleterious	2,31	18,22	0,26	0,45	disease	0,5	disease	0,96	disease	0,78	disease	0,88	8	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,87	low_impact	-2,63	medium_impact	0,01	high_impact	2,22	0,61	0,8	18,58	14,48	N	0,5	N	0,91	NA	NA	0,84	rs386829213	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14485	14485	C	G	MI.23794	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	189	63	M	I	atG/atC	-2,11	0	0	probably_damaging	0,99	neutral	0,31	neutral	2,72	deleterious	-3,54	deleterious	-3,99	high_impact	4,01	damaging	0,44	damaging	0,02	neutral	1,78	14,88	0,26	0,45	disease	0,5	disease	0,96	disease	0,78	disease	0,88	8	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,87	low_impact	-2,63	medium_impact	0,01	high_impact	2,22	0,61	0,8	18,58	14,48	N	0,49	N	0,91	NA	NA	0,84	rs386829213	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14486	14486	A	G	MI.23795	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	188	63	M	T	aTg/aCg	-3,49	0	0	probably_damaging	0,99	neutral	0,07	neutral	2,18	deleterious	-5,03	deleterious	-5,98	high_impact	4,01	damaging	0,44	damaging	0,05	neutral	1,5	13,29	0,2	0,45	disease	0,72	disease	0,96	disease	0,78	disease	0,88	8	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,91	low_impact	-2,63	medium_impact	-0,42	high_impact	2,22	0,36	0,8	18,58	14,48	P	0,52	P	0,96	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14486	14486	A	T	MI.23796	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	188	63	M	K	aTg/aAg	-3,49	0	0	probably_damaging	0,99	deleterious	0,02	neutral	2,13	deleterious	-5,38	deleterious	-5,98	high_impact	4,01	damaging	0,52	damaging	0,02	deleterious	3,33	22,9	0,14	0,4	disease	0,77	disease	0,98	disease	0,83	disease	0,9	8	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,91	low_impact	-2,63	medium_impact	-0,73	high_impact	2,22	0,51	0,8	18,58	14,48	N	0,35	N	0,98	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14487	14487	T	A	MI.23797	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	187	63	M	L	Atg/Ttg	8,21	1	0	probably_damaging	0,98	neutral	0,57	neutral	2,36	neutral	-2,47	deleterious	-2,99	high_impact	4,01	damaging	0,44	damaging	0,06	neutral	1,79	14,94	0,19	0,45	neutral	0,34	disease	0,95	disease	0,75	disease	0,87	7	neutral	0,98	neutral	0,3	deleterious	2	deleterious	0,84	low_impact	-2,35	medium_impact	0,27	high_impact	2,22	0,45	0,8	18,58	14,48	P	0,73	P	0,97	NA	NA	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14487	14487	T	G	MI.23798	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	187	63	M	L	Atg/Ctg	8,21	1	0	probably_damaging	0,98	neutral	0,57	neutral	2,36	neutral	-2,47	deleterious	-2,99	high_impact	4,01	damaging	0,44	damaging	0,06	neutral	1,68	14,29	0,19	0,45	neutral	0,34	disease	0,95	disease	0,75	disease	0,87	7	neutral	0,98	neutral	0,3	deleterious	2	deleterious	0,84	low_impact	-2,35	medium_impact	0,27	high_impact	2,22	0,45	0,8	18,58	14,48	P	0,66	P	0,97	NA	NA	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14487	14487	T	C	MI.23799	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	187	63	M	V	Atg/Gtg	8,21	1	0	probably_damaging	0,99	neutral	0,42	neutral	2,39	deleterious	-3,62	deleterious	-3,98	high_impact	4,01	damaging	0,28	damaging	0,04	deleterious	0,66	8,55	0,25	0,45	disease	0,52	disease	0,96	disease	0,79	disease	0,88	8	deleterious	0,99	neutral	0,22	deleterious	2	deleterious	0,87	low_impact	-2,63	medium_impact	0,13	high_impact	2,22	0,48	0,8	18,58	14,48	P	0,9	P	0,93	NA	NA	0,85	rs199476109	Pathogenic|Pathogenic|Pathogenic	Leigh_syndrome_due_to_mitochondrial_complex_I_deficiency|Striatal_necrosis,_bilateral,_with_dystonia|Leigh_syndrome	RCV000010333.2|RCV000010334.2|RCV000144020.2	MedGen|MedGen|MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	T14487C	Dystonia/Leigh Disease/Ataxia/Ptosis/Epilepsy	-	+	Cfrm	20
chrM	8638	8638	A	C	MI.238	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	112	38	I	L	Atc/Ctc	-0,1	0	0	probably_damaging	0,93	neutral	0,87	neutral	4,34	neutral	-0,55	neutral	-0,86	neutral_impact	0,04	neutral	0,94	neutral	0,94	neutral	1,01	10,73	0,47	0,65	neutral	0,47	neutral	0,16	neutral	0,17	neutral	0,27	5	neutral	0,92	deleterious	0,47	neutral	-2	deleterious	0,61	low_impact	-1,82	medium_impact	0,76	low_impact	-1,06	0,49	0,9	15,49	18,25	N	0,33	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6136	6136	T	C	MI.2380	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	233	78	F	S	tTt/tCt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-4,35	deleterious	-5,34	high_impact	4,82	damaging	0,56	neutral	0,62	deleterious	2,49	19,4	0,27	0,55	neutral	0,34	disease	0,86	disease	0,72	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	3,35	0,41	0,9	1,56	8,79	P	0,62	P	0,84	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14489	14489	C	T	MI.23800	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	185	62	G	E	gGa/gAa	-20	0	0	probably_damaging	1	neutral	0,27	neutral	1,57	deleterious	-7,13	deleterious	-7,98	high_impact	4,01	damaging	0,5	damaging	0,02	deleterious	4,1	23,7	0,18	0,45	disease	0,84	disease	0,96	disease	0,85	disease	0,91	8	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,03	high_impact	2,22	0,6	0,8	18,14	14,91	N	0,39	N	1	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14489	14489	C	G	MI.23801	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	185	62	G	A	gGa/gCa	-20	0	0	probably_damaging	1	neutral	0,51	neutral	2,41	deleterious	-6,07	deleterious	-5,99	high_impact	3,66	damaging	0,51	damaging	0,05	deleterious	3,32	22,9	0,16	0,45	disease	0,71	disease	0,89	disease	0,78	disease	0,82	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	0,22	medium_impact	1,93	0,65	0,8	18,14	14,91	N	0,32	N	0,78	NA	NA	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14489	14489	C	A	MI.23802	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	185	62	G	V	gGa/gTa	-20	0	0	probably_damaging	1	neutral	0,57	neutral	1,58	deleterious	-7,52	deleterious	-8,98	high_impact	4,01	damaging	0,42	damaging	0,02	deleterious	4,12	23,8	0,13	0,4	disease	0,87	disease	0,97	disease	0,82	disease	0,92	8	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	0,27	high_impact	2,22	0,59	0,8	18,14	14,91	N	0,44	N	0,98	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14490	14490	C	G	MI.23803	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	184	62	G	R	Gga/Cga	2,71	0,97	0	probably_damaging	1	neutral	0,35	neutral	1,56	deleterious	-7,73	deleterious	-7,98	high_impact	4,01	damaging	0,48	damaging	0,01	deleterious	4,14	23,8	0,17	0,45	disease	0,88	disease	0,97	disease	0,86	disease	0,92	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	0,06	high_impact	2,22	0,72	0,85	18,14	14,91	P	0,57	P	1	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14490	14490	C	A	MI.23804	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	184	62	G	W	Gga/Tga	2,71	0,97	0	probably_damaging	1	neutral	0,18	neutral	1,55	deleterious	-10,14	deleterious	-7,97	high_impact	4,01	damaging	0,49	damaging	0,01	deleterious	4,77	24,7	0,16	0,45	disease	0,97	disease	0,96	disease	0,82	disease	0,91	8	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,16	high_impact	2,22	0,47	0,8	18,14	14,91	P	0,52	P	1	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14492	14492	C	G	MI.23805	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	182	61	G	A	gGg/gCg	-8,76	0	0	probably_damaging	1	neutral	0,28	neutral	0,4	deleterious	-6,55	deleterious	-5,99	high_impact	4,01	damaging	0,5	damaging	0,04	deleterious	3,32	22,9	0,17	0,45	disease	0,71	disease	0,91	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	-0,02	high_impact	2,22	0,64	0,8	48,67	8,33	N	0,37	N	0,78	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14492	14492	C	A	MI.23806	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	182	61	G	V	gGg/gTg	-8,76	0	0	probably_damaging	1	neutral	0,62	neutral	0,38	deleterious	-7,02	deleterious	-8,98	high_impact	4,01	damaging	0,42	damaging	0,02	deleterious	4,18	23,8	0,14	0,4	disease	0,87	disease	0,97	disease	0,8	disease	0,91	8	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0,32	high_impact	2,22	0,61	0,8	48,67	8,33	N	0,41	N	0,98	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14492	14492	C	T	MI.23807	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	182	61	G	E	gGg/gAg	-8,76	0	0	probably_damaging	1	neutral	0,13	neutral	0,36	deleterious	-9,67	deleterious	-7,99	high_impact	4,01	damaging	0,5	damaging	0,02	deleterious	4,13	23,8	0,16	0,45	disease	0,84	disease	0,96	disease	0,84	disease	0,92	8	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,25	high_impact	2,22	0,62	0,8	48,67	8,33	N	0,4	N	1	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14493	14493	C	G	MI.23808	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	181	61	G	R	Ggg/Cgg	4,31	0,99	0	probably_damaging	1	neutral	0,17	neutral	0,36	deleterious	-9,8	deleterious	-7,99	high_impact	4,01	damaging	0,48	damaging	0,01	deleterious	4,09	23,7	0,15	0,4	disease	0,88	disease	0,97	disease	0,85	disease	0,91	8	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	-0,18	high_impact	2,22	0,7	0,85	48,67	8,33	P	0,61	P	1	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14493	14493	C	A	MI.23809	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	181	61	G	W	Ggg/Tgg	4,31	0,99	0	probably_damaging	1	neutral	0,1	neutral	0,35	deleterious	-12,56	deleterious	-7,99	high_impact	4,01	damaging	0,49	damaging	0,01	deleterious	4,7	24,6	0,14	0,4	disease	0,97	disease	0,97	disease	0,82	disease	0,9	8	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,32	high_impact	2,22	0,41	0,8	48,67	8,33	P	0,5	N	1	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6136	6136	T	A	MI.2381	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	233	78	F	Y	tTt/tAt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-4,54	neutral	-2	high_impact	4,01	neutral	0,62	neutral	0,48	deleterious	3,86	23,5	0,3	0,55	disease	0,69	disease	0,81	disease	0,69	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,6	0,65	0,9	1,56	8,79	P	0,59	P	0,59	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14494	14494	T	A	MI.23810	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	180	60	L	F	ttA/ttT	5,46	0,99	0	probably_damaging	1	neutral	0,52	neutral	2,14	deleterious	-4,53	deleterious	-3,99	high_impact	3,66	neutral	0,66	neutral	0,3	deleterious	3,8	23,4	0,32	0,5	disease	0,55	disease	0,88	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-3,55	medium_impact	0,23	medium_impact	1,93	0,68	0,85	26,99	19,59	P	0,61	P	0,95	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14494	14494	T	G	MI.23811	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	180	60	L	F	ttA/ttC	5,46	0,99	0	probably_damaging	1	neutral	0,52	neutral	2,14	deleterious	-4,53	deleterious	-3,99	high_impact	3,66	neutral	0,66	neutral	0,3	deleterious	3,66	23,2	0,32	0,5	disease	0,55	disease	0,88	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-3,55	medium_impact	0,23	medium_impact	1,93	0,68	0,85	26,99	19,59	P	0,61	P	0,95	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14495	14495	A	C	MI.23812	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	179	60	L	W	tTa/tGa	-4,86	0	0	probably_damaging	1	neutral	0,12	neutral	2,1	deleterious	-7,73	deleterious	-5,99	high_impact	4	damaging	0,5	damaging	0,25	deleterious	3,29	22,8	0,15	0,45	disease	0,9	disease	0,91	disease	0,78	disease	0,88	8	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,87	low_impact	-3,55	medium_impact	-0,27	high_impact	2,21	0,68	0,85	26,99	19,59	N	0,42	N	0,98	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14495	14495	A	G	MI.23813	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	179	60	L	S	tTa/tCa	-4,86	0	0	probably_damaging	1	neutral	0,29	neutral	2,17	deleterious	-6,14	deleterious	-5,99	high_impact	3,66	damaging	0,23	damaging	0,17	deleterious	3,77	23,4	0,19	0,45	disease	0,82	disease	0,91	disease	0,75	disease	0,84	7	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	-0,01	medium_impact	1,93	0,64	0,8	26,99	19,59	P	0,87	P	0,97	NA	NA	0,84	rs199476106	Pathogenic	Leber's_optic_atrophy	RCV000010330.2	MedGen:OMIM:SNOMED_CT	.	.	.	.	A14495G	LHON	-	+	Cfrm	7
chrM	14496	14496	A	T	MI.23814	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	178	60	L	M	Tta/Ata	8,44	1	0	probably_damaging	1	neutral	0,19	neutral	2,14	deleterious	-3,75	neutral	-2	high_impact	3,66	damaging	0,58	neutral	0,42	deleterious	3,26	22,8	0,25	0,45	neutral	0,33	disease	0,84	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,75	low_impact	-3,55	medium_impact	-0,14	medium_impact	1,93	0,72	0,85	26,99	19,59	P	0,65	P	0,87	NA	NA	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14496	14496	A	C	MI.23815	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	178	60	L	V	Tta/Gta	8,44	1	0	probably_damaging	1	neutral	0,4	neutral	2,69	deleterious	-3,35	deleterious	-2,99	high_impact	3,66	damaging	0,52	damaging	0,23	deleterious	3,03	22,3	0,36	0,5	neutral	0,44	disease	0,89	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,82	low_impact	-3,55	medium_impact	0,11	medium_impact	1,93	0,7	0,85	26,99	19,59	P	0,71	P	0,71	NA	NA	0,65	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14498	14498	T	C	MI.23816	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	176	59	Y	C	tAt/tGt	3,85	1	0	probably_damaging	1	neutral	0,11	neutral	1,32	deleterious	-7,64	deleterious	-8,85	high_impact	4,01	damaging	0,2	damaging	0,02	deleterious	3,37	22,9	0,32	0,5	disease	0,92	disease	0,95	disease	0,84	disease	0,91	8	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,3	high_impact	2,22	0,33	0,8	24,34	15,68	P	0,86	P	1	NA	NA	0,85	rs869025186	Pathogenic	Leber's_optic_atrophy	RCV000055702.1	MedGen:OMIM:SNOMED_CT	.	.	.	.	T14498C	LHON	+	+	Reported	4
chrM	14498	14498	T	G	MI.23817	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	176	59	Y	S	tAt/tCt	3,85	1	0	probably_damaging	1	neutral	0,25	neutral	1,33	deleterious	-5,96	deleterious	-8,85	high_impact	4,01	damaging	0,4	damaging	0,06	deleterious	3,93	23,5	0,24	0,45	disease	0,81	disease	0,93	disease	0,79	disease	0,88	8	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	-0,06	high_impact	2,22	0,33	0,8	24,34	15,68	P	0,71	P	0,96	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14498	14498	T	A	MI.23818	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	176	59	Y	F	tAt/tTt	3,85	1	0	probably_damaging	1	neutral	0,51	neutral	1,45	neutral	-2,72	deleterious	-3,76	high_impact	3,66	damaging	0,53	damaging	0,06	deleterious	3,75	23,3	0,24	0,45	neutral	0,45	disease	0,92	disease	0,79	disease	0,81	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-3,55	medium_impact	0,22	medium_impact	1,93	0,52	0,8	24,34	15,68	P	0,62	P	0,8	NA	NA	0,85	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	14499	14499	A	G	MI.23819	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	175	59	Y	H	Tat/Cat	2,94	1	0	probably_damaging	1	neutral	0,32	neutral	1,32	deleterious	-5,4	deleterious	-4,96	high_impact	4,01	damaging	0,44	damaging	0,03	deleterious	3,3	22,8	0,25	0,45	disease	0,76	disease	0,93	disease	0,86	disease	0,89	8	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,87	low_impact	-3,55	medium_impact	0,03	high_impact	2,22	0,4	0,8	24,34	15,68	P	0,73	P	0,98	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6137	6137	T	A	MI.2382	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	234	78	F	L	ttT/ttA	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,84	neutral	-1,32	deleterious	-4	high_impact	3,64	damaging	0,54	neutral	0,61	deleterious	3,9	23,5	0,42	0,55	neutral	0,29	disease	0,82	disease	0,67	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	high_impact	2,26	0,57	0,9	1,56	8,79	P	0,56	P	0,83	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14499	14499	A	T	MI.23820	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	175	59	Y	N	Tat/Aat	2,94	1	0	probably_damaging	1	neutral	0,19	neutral	1,33	deleterious	-6,34	deleterious	-8,88	high_impact	4,01	damaging	0,31	damaging	0,05	deleterious	3,33	22,9	0,25	0,45	disease	0,84	disease	0,93	disease	0,8	disease	0,88	8	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,55	medium_impact	-0,14	high_impact	2,22	0,27	0,8	24,34	15,68	P	0,75	P	1	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14499	14499	A	C	MI.23821	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	175	59	Y	D	Tat/Gat	2,94	1	0	probably_damaging	1	neutral	0,12	neutral	1,31	deleterious	-7,13	deleterious	-9,85	high_impact	4,01	damaging	0,38	damaging	0,03	deleterious	3,3	22,9	0,16	0,45	disease	0,87	disease	0,95	disease	0,85	disease	0,91	8	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,87	low_impact	-3,55	medium_impact	-0,27	high_impact	2,22	0,27	0,8	24,34	15,68	P	0,75	P	0,97	NA	NA	0,86	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14500	14500	A	T	MI.23822	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	174	58	I	M	atT/atA	5,46	1	0	possibly_damaging	0,79	neutral	0,18	neutral	1,95	deleterious	-3,13	deleterious	-2,68	medium_impact	3,44	damaging	0,6	neutral	0,41	deleterious	2,93	22	0,33	0,5	disease	0,61	disease	0,86	disease	0,69	disease	0,76	5	neutral	0,89	neutral	0,2	NA	0	deleterious	0,7	low_impact	-1,32	medium_impact	-0,16	medium_impact	1,74	0,77	0,85	40,71	8,78	P	0,65	P	0,77	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14500	14500	A	C	MI.23823	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	174	58	I	M	atT/atG	5,46	1	0	possibly_damaging	0,79	neutral	0,18	neutral	1,95	deleterious	-3,13	deleterious	-2,68	medium_impact	3,44	damaging	0,6	neutral	0,41	deleterious	2,82	21,5	0,33	0,5	disease	0,61	disease	0,86	disease	0,69	disease	0,76	5	neutral	0,89	neutral	0,2	NA	0	deleterious	0,7	low_impact	-1,32	medium_impact	-0,16	medium_impact	1,74	0,77	0,85	40,71	8,78	P	0,54	P	0,77	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14501	14501	A	C	MI.23824	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	173	58	I	S	aTt/aGt	-0,27	0,08	0,01	possibly_damaging	0,62	neutral	0,2	neutral	1,94	deleterious	-3,52	deleterious	-5,67	high_impact	3,78	damaging	0,47	neutral	0,4	deleterious	3,38	22,9	0,22	0,45	disease	0,76	disease	0,93	disease	0,65	disease	0,78	6	neutral	0,81	neutral	0,29	deleterious	1	deleterious	0,72	medium_impact	-0,99	medium_impact	-0,13	high_impact	2,03	0,51	0,8	40,71	8,78	N	0,48	N	0,97	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14501	14501	A	G	MI.23825	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	173	58	I	T	aTt/aCt	-0,27	0,08	0,01	possibly_damaging	0,46	neutral	0,07	neutral	1,93	deleterious	-3,92	deleterious	-4,35	high_impact	3,78	neutral	0,67	neutral	0,43	neutral	1,64	14,09	0,36	0,5	disease	0,63	disease	0,9	disease	0,67	disease	0,76	5	neutral	0,92	neutral	0,31	deleterious	1	deleterious	0,55	medium_impact	-0,73	medium_impact	-0,42	high_impact	2,03	0,62	0,8	40,71	8,78	N	0,46	N	0,91	NA	NA	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14501	14501	A	T	MI.23826	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	173	58	I	N	aTt/aAt	-0,27	0,08	0,01	possibly_damaging	0,88	deleterious	0,04	neutral	1,91	deleterious	-6,06	deleterious	-6,67	high_impact	3,78	damaging	0,54	neutral	0,37	deleterious	3,69	23,3	0,28	0,45	disease	0,86	disease	0,93	disease	0,69	disease	0,81	6	deleterious	0,98	neutral	0,08	deleterious	5	deleterious	0,81	low_impact	-1,59	medium_impact	-0,56	high_impact	2,03	0,55	0,8	40,71	8,78	N	0,4	N	0,99	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14502	14502	T	C	MI.23827	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	172	58	I	V	Att/Gtt	5,46	0,8	0,01	benign	0,02	neutral	0,45	neutral	2,75	neutral	1,24	neutral	-0,37	low_impact	1,23	neutral	0,97	neutral	0,92	neutral	-0,98	0,02	0,43	0,55	neutral	0,18	neutral	0,47	neutral	0,44	neutral	0,41	2	neutral	0,53	deleterious	0,72	neutral	-6	neutral	0,14	medium_impact	0,75	medium_impact	0,16	medium_impact	-0,11	0,66	0,8	40,71	8,78	N	0,46	N	0,08	NA	NA	0,22	rs201327354	.	.	.	.	.	.	.	.	T14502C	LHON	+	-	Reported-possibly synergistic	4
chrM	14502	14502	T	A	MI.23828	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	172	58	I	F	Att/Ttt	5,46	0,8	0,01	benign	0,03	neutral	0,34	neutral	1,92	deleterious	-4,67	deleterious	-3,99	high_impact	3,78	damaging	0,53	neutral	0,38	deleterious	2,16	17,25	0,32	0,5	disease	0,66	disease	0,92	disease	0,69	disease	0,78	6	neutral	0,64	deleterious	0,66	neutral	-2	neutral	0,31	medium_impact	0,59	medium_impact	0,05	high_impact	2,03	0,7	0,85	40,71	8,78	P	0,55	P	0,92	NA	NA	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14502	14502	T	G	MI.23829	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	172	58	I	L	Att/Ctt	5,46	0,8	0,01	benign	0,15	neutral	0,52	neutral	2,04	neutral	-1,67	neutral	-2	medium_impact	3,23	damaging	0,55	neutral	0,43	deleterious	2,1	16,85	0,3	0,45	neutral	0,32	disease	0,89	disease	0,64	disease	0,74	5	neutral	0,38	deleterious	0,69	neutral	-3	neutral	0,3	medium_impact	-0,11	medium_impact	0,23	medium_impact	1,57	0,66	0,8	40,71	8,78	N	0,53	P	0,65	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6137	6137	T	G	MI.2383	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	234	78	F	L	ttT/ttG	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,84	neutral	-1,32	deleterious	-4	high_impact	3,64	damaging	0,54	neutral	0,61	deleterious	3,81	23,4	0,42	0,55	neutral	0,29	disease	0,82	disease	0,67	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	high_impact	2,26	0,57	0,9	1,56	8,79	P	0,56	P	0,83	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14503	14503	T	G	MI.23830	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	171	57	L	F	ttA/ttC	0,18	0,02	0	probably_damaging	0,92	neutral	0,39	neutral	1,71	deleterious	-4,16	deleterious	-3,99	high_impact	3,63	damaging	0,42	damaging	0,24	deleterious	3,62	23,2	0,27	0,45	disease	0,55	disease	0,89	disease	0,72	disease	0,79	6	neutral	0,93	neutral	0,24	deleterious	2	deleterious	0,81	low_impact	-1,77	medium_impact	0,1	medium_impact	1,9	0,62	0,8	14,16	15,31	N	0,49	N	0,95	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14503	14503	T	A	MI.23831	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	171	57	L	F	ttA/ttT	0,18	0,02	0	probably_damaging	0,92	neutral	0,39	neutral	1,71	deleterious	-4,16	deleterious	-3,99	high_impact	3,63	damaging	0,42	damaging	0,24	deleterious	3,86	23,5	0,27	0,45	disease	0,55	disease	0,89	disease	0,72	disease	0,79	6	neutral	0,93	neutral	0,24	deleterious	2	deleterious	0,81	low_impact	-1,77	medium_impact	0,1	medium_impact	1,9	0,62	0,8	14,16	15,31	N	0,48	N	0,95	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14504	14504	A	G	MI.23832	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	170	57	L	S	tTa/tCa	-2,57	0	0	probably_damaging	0,98	neutral	0,07	neutral	1,67	deleterious	-6,23	deleterious	-5,98	high_impact	3,98	damaging	0,38	damaging	0,28	deleterious	3,75	23,3	0,16	0,45	disease	0,82	disease	0,92	disease	0,74	disease	0,83	7	deleterious	0,99	neutral	0,05	deleterious	2	deleterious	0,87	low_impact	-2,35	medium_impact	-0,42	high_impact	2,19	0,64	0,8	14,16	15,31	P	0,57	P	0,97	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14504	14504	A	C	MI.23833	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	170	57	L	W	tTa/tGa	-2,57	0	0	benign	0,34	deleterious	0,01	neutral	1,66	deleterious	-8,05	deleterious	-5,98	high_impact	3,98	damaging	0,35	damaging	0,24	neutral	1,49	13,24	0,12	0,4	disease	0,9	disease	0,92	disease	0,76	disease	0,86	7	deleterious	0,99	neutral	0,34	deleterious	2	deleterious	0,47	medium_impact	-0,53	medium_impact	-0,9	high_impact	2,19	0,59	0,8	14,16	15,31	P	0,58	P	0,98	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14505	14505	A	C	MI.23834	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	169	57	L	V	Tta/Gta	3,63	1	0	probably_damaging	0,92	neutral	0,21	neutral	1,79	neutral	-2,59	deleterious	-2,99	high_impact	3,98	damaging	0,26	damaging	0,23	deleterious	2,96	22,1	0,28	0,45	neutral	0,44	disease	0,91	disease	0,73	disease	0,8	6	neutral	0,95	neutral	0,15	deleterious	2	deleterious	0,8	low_impact	-1,77	medium_impact	-0,11	high_impact	2,19	0,73	0,85	14,16	15,31	P	0,92	P	0,71	NA	NA	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14505	14505	A	T	MI.23835	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	169	57	L	M	Tta/Ata	3,63	1	0	probably_damaging	0,98	neutral	0,27	neutral	1,77	neutral	-2,9	neutral	-2	medium_impact	2,6	neutral	0,8	neutral	0,58	deleterious	3,24	22,8	0,23	0,45	neutral	0,33	disease	0,7	disease	0,7	disease	0,56	1	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,75	low_impact	-2,35	medium_impact	-0,03	medium_impact	1,04	0,61	0,8	14,16	15,31	N	0,5	N	0,87	NA	NA	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14506	14506	A	C	MI.23836	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	168	56	F	L	ttT/ttG	2,25	1	0	probably_damaging	1	neutral	0,83	neutral	2,37	neutral	-1,74	deleterious	-5,99	medium_impact	2,2	neutral	0,7	damaging	0,16	deleterious	1,87	15,38	0,3	0,45	neutral	0,21	disease	0,89	disease	0,52	disease	0,57	1	deleterious	1	neutral	0,42	deleterious	1	deleterious	0,76	low_impact	-3,55	medium_impact	0,59	medium_impact	0,7	0,68	0,85	50	8,48	N	0,36	N	0,9	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14506	14506	A	T	MI.23837	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	168	56	F	L	ttT/ttA	2,25	1	0	probably_damaging	1	neutral	0,83	neutral	2,37	neutral	-1,74	deleterious	-5,99	medium_impact	2,2	neutral	0,7	damaging	0,16	deleterious	1,95	15,91	0,3	0,45	neutral	0,21	disease	0,89	disease	0,52	disease	0,57	1	deleterious	1	neutral	0,42	deleterious	1	deleterious	0,76	low_impact	-3,55	medium_impact	0,59	medium_impact	0,7	0,68	0,85	50	8,48	N	0,35	N	0,9	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14507	14507	A	T	MI.23838	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	167	56	F	Y	tTt/tAt	1,79	1	0	probably_damaging	1	neutral	0,24	neutral	2,14	deleterious	-3,3	deleterious	-2,99	medium_impact	2,99	neutral	0,69	damaging	0,12	deleterious	3,38	23	0,22	0,45	neutral	0,4	disease	0,94	disease	0,64	disease	0,8	6	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,82	low_impact	-3,55	medium_impact	-0,07	medium_impact	1,37	0,64	0,8	50	8,48	N	0,42	N	0,88	NA	NA	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14507	14507	A	C	MI.23839	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	167	56	F	C	tTt/tGt	1,79	1	0	probably_damaging	1	deleterious	0,02	neutral	2,12	deleterious	-6,26	deleterious	-7,98	high_impact	3,88	neutral	0,6	damaging	0,09	deleterious	3,39	23	0,21	0,45	disease	0,86	disease	0,96	disease	0,69	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,55	medium_impact	-0,73	high_impact	2,11	0,42	0,8	50	8,48	P	0,51	P	0,98	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6138	6138	G	T	MI.2384	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	235	79	G	C	Ggc/Tgc	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-4,39	deleterious	-6,03	high_impact	5,13	damaging	0,4	damaging	0,01	deleterious	4,06	23,7	0,2	0,55	disease	0,81	disease	0,94	disease	0,69	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,64	0,56	0,9	1,95	6,64	P	0,57	P	0,98	disease_causing	0,99	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14507	14507	A	G	MI.23840	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	167	56	F	S	tTt/tCt	1,79	1	0	probably_damaging	1	neutral	0,08	neutral	2,13	deleterious	-4,88	deleterious	-7,98	high_impact	3,88	damaging	0,52	damaging	0,12	deleterious	3,91	23,5	0,22	0,45	disease	0,74	disease	0,95	disease	0,65	disease	0,81	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	-0,38	high_impact	2,11	0,58	0,8	50	8,48	P	0,53	P	0,97	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14508	14508	A	G	MI.23841	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	166	56	F	L	Ttt/Ctt	6,61	1	0	probably_damaging	1	neutral	0,83	neutral	2,37	neutral	-1,74	deleterious	-5,99	medium_impact	2,2	neutral	0,7	damaging	0,16	deleterious	1,97	16,01	0,3	0,45	neutral	0,21	disease	0,89	disease	0,52	disease	0,57	1	deleterious	1	neutral	0,42	deleterious	1	deleterious	0,76	low_impact	-3,55	medium_impact	0,59	medium_impact	0,7	0,68	0,85	50	8,48	N	0,46	N	0,9	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14508	14508	A	C	MI.23842	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	166	56	F	V	Ttt/Gtt	6,61	1	0	probably_damaging	1	neutral	0,36	neutral	2,28	neutral	-2,82	deleterious	-6,99	medium_impact	2,79	neutral	0,7	damaging	0,24	deleterious	3,15	22,6	0,25	0,45	neutral	0,48	disease	0,96	disease	0,64	disease	0,6	2	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,83	low_impact	-3,55	medium_impact	0,07	medium_impact	1,2	0,68	0,85	50	8,48	N	0,51	P	0,95	NA	NA	0,62	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14508	14508	A	T	MI.23843	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	166	56	F	I	Ttt/Att	6,61	1	0	probably_damaging	1	neutral	0,51	neutral	2,54	deleterious	-3,02	deleterious	-5,99	high_impact	3,88	neutral	0,62	damaging	0,12	deleterious	3,42	23	0,19	0,45	neutral	0,45	disease	0,96	disease	0,63	disease	0,81	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,55	medium_impact	0,22	high_impact	2,11	0,72	0,85	50	8,48	P	0,58	P	0,92	NA	NA	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14510	14510	A	G	MI.23844	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	164	55	V	A	gTt/gCt	-6,7	0	0	possibly_damaging	0,46	deleterious	0,03	neutral	2,23	deleterious	-3,38	deleterious	-3,87	medium_impact	3,39	neutral	0,73	neutral	0,55	neutral	1,76	14,76	0,3	0,45	neutral	0,39	disease	0,72	disease	0,58	disease	0,72	4	neutral	0,97	neutral	0,29	deleterious	4	deleterious	0,47	medium_impact	-0,73	medium_impact	-0,63	medium_impact	1,7	0,47	0,8	49,12	8,68	N	0,42	N	0,69	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14510	14510	A	T	MI.23845	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	164	55	V	D	gTt/gAt	-6,7	0	0	probably_damaging	0,93	deleterious	0,01	neutral	2,17	deleterious	-6,28	deleterious	-6,81	medium_impact	3,39	damaging	0,53	neutral	0,38	deleterious	3,72	23,3	0,12	0,4	disease	0,81	disease	0,91	disease	0,7	disease	0,83	7	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,82	low_impact	-1,83	medium_impact	-0,9	medium_impact	1,7	0,68	0,85	49,12	8,68	N	0,32	N	0,94	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14510	14510	A	C	MI.23846	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	164	55	V	G	gTt/gGt	-6,7	0	0	possibly_damaging	0,82	neutral	0,15	neutral	2,18	deleterious	-5,28	deleterious	-6,8	medium_impact	3,04	damaging	0,5	neutral	0,49	deleterious	3,03	22,3	0,17	0,45	disease	0,73	disease	0,81	disease	0,59	disease	0,77	5	neutral	0,92	neutral	0,17	NA	0	deleterious	0,77	low_impact	-1,4	medium_impact	-0,21	medium_impact	1,41	0,58	0,8	49,12	8,68	N	0,38	N	0,86	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14511	14511	C	G	MI.23847	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	163	55	V	L	Gtt/Ctt	4,54	0,39	0	benign	0,04	neutral	1	neutral	2,49	neutral	0,45	deleterious	-2,75	neutral_impact	0,52	neutral	0,68	neutral	0,54	neutral	1,74	14,63	0,37	0,5	neutral	0,12	neutral	0,33	neutral	0,35	neutral	0,43	1	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,13	medium_impact	0,47	high_impact	1,87	medium_impact	-0,7	0,7	0,85	49,12	8,68	N	0,37	N	0,57	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14511	14511	C	T	MI.23848	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	163	55	V	I	Gtt/Att	4,54	0,39	0	benign	0,33	neutral	0,17	neutral	2,32	neutral	-0,35	neutral	-0,94	medium_impact	3,39	damaging	0,51	neutral	0,48	deleterious	1,96	15,98	0,4	0,5	neutral	0,21	disease	0,66	disease	0,54	disease	0,7	4	neutral	0,8	neutral	0,42	neutral	-3	neutral	0,38	medium_impact	-0,51	medium_impact	-0,18	medium_impact	1,7	0,84	0,9	49,12	8,68	P	0,53	P	0,39	NA	NA	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14511	14511	C	A	MI.23849	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	163	55	V	F	Gtt/Ttt	4,54	0,39	0	possibly_damaging	0,79	neutral	0,36	neutral	2,25	neutral	-1,4	deleterious	-4,75	medium_impact	2,58	damaging	0,58	neutral	0,48	deleterious	3,91	23,5	0,18	0,45	disease	0,53	disease	0,88	disease	0,54	disease	0,74	5	neutral	0,81	neutral	0,29	NA	0	deleterious	0,72	low_impact	-1,32	medium_impact	0,07	medium_impact	1,02	0,7	0,85	49,12	8,68	N	0,41	N	0,9	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6138	6138	G	C	MI.2385	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	235	79	G	R	Ggc/Cgc	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-3,22	deleterious	-5,36	high_impact	5,13	damaging	0,44	damaging	0,02	deleterious	3,81	23,4	0,16	0,55	disease	0,63	disease	0,95	disease	0,78	disease	0,89	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,64	0,66	0,9	1,95	6,64	P	0,63	P	0,95	disease_causing	0,99	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14512	14512	T	A	MI.23850	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	162	54	M	I	atA/atT	-0,04	0	0	benign	0,01	neutral	0,64	neutral	2,43	neutral	0,86	deleterious	-3,53	low_impact	1,5	neutral	0,83	neutral	0,93	neutral	1,04	10,89	0,36	0,5	neutral	0,14	disease	0,69	neutral	0,42	disease	0,53	1	neutral	0,34	deleterious	0,82	neutral	-6	neutral	0,2	medium_impact	1,03	medium_impact	0,35	medium_impact	0,12	0,72	0,85	28,32	24,19	N	0,28	N	0,8	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14512	14512	T	G	MI.23851	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	162	54	M	I	atA/atC	-0,04	0	0	benign	0,01	neutral	0,64	neutral	2,43	neutral	0,86	deleterious	-3,53	low_impact	1,5	neutral	0,83	neutral	0,93	deleterious	0,71	8,9	0,36	0,5	neutral	0,14	disease	0,69	neutral	0,42	disease	0,53	1	neutral	0,34	deleterious	0,82	neutral	-6	neutral	0,2	medium_impact	1,03	medium_impact	0,35	medium_impact	0,12	0,72	0,85	28,32	24,19	N	0,28	N	0,8	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14513	14513	A	T	MI.23852	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	161	54	M	K	aTa/aAa	-9,45	0	0	possibly_damaging	0,46	deleterious	0,03	neutral	2,2	neutral	-2,74	deleterious	-5,77	medium_impact	3,44	neutral	0,68	neutral	0,35	deleterious	2,16	17,23	0,13	0,4	disease	0,56	disease	0,94	disease	0,67	disease	0,87	7	neutral	0,97	neutral	0,29	deleterious	4	deleterious	0,6	medium_impact	-0,73	medium_impact	-0,63	medium_impact	1,74	0,64	0,8	28,32	24,19	N	0,36	N	0,95	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14513	14513	A	G	MI.23853	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	161	54	M	T	aTa/aCa	-9,45	0	0	benign	0,2	neutral	0,07	neutral	2,41	neutral	-1,58	deleterious	-5,62	medium_impact	2,75	neutral	0,79	neutral	0,71	neutral	1,24	11,93	0,28	0,45	neutral	0,38	disease	0,84	disease	0,57	disease	0,8	6	neutral	0,92	neutral	0,44	neutral	-3	neutral	0,41	medium_impact	-0,24	medium_impact	-0,42	medium_impact	1,16	0,51	0,8	28,32	24,19	N	0,31	N	0,87	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14514	14514	T	A	MI.23854	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	160	54	M	L	Ata/Tta	4,31	0,22	0	benign	0,02	neutral	0,98	neutral	2,42	neutral	0,13	deleterious	-2,76	medium_impact	2,35	neutral	0,87	neutral	0,68	deleterious	0,59	8,07	0,29	0,45	neutral	0,18	disease	0,86	neutral	0,42	disease	0,73	5	neutral	0	deleterious	0,98	neutral	-3	neutral	0,23	medium_impact	0,75	medium_impact	1,15	medium_impact	0,83	0,68	0,85	28,32	24,19	N	0,36	N	0,71	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14514	14514	T	G	MI.23855	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	160	54	M	L	Ata/Cta	4,31	0,22	0	benign	0,02	neutral	0,98	neutral	2,42	neutral	0,13	deleterious	-2,76	medium_impact	2,35	neutral	0,87	neutral	0,68	deleterious	0,49	7,36	0,29	0,45	neutral	0,18	disease	0,86	neutral	0,42	disease	0,73	5	neutral	0	deleterious	0,98	neutral	-3	neutral	0,23	medium_impact	0,75	medium_impact	1,15	medium_impact	0,83	0,68	0,85	28,32	24,19	N	0,39	N	0,71	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14514	14514	T	C	MI.23856	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	160	54	M	V	Ata/Gta	4,31	0,22	0	benign	0	neutral	1	neutral	2,36	neutral	1,74	deleterious	-3,47	low_impact	1,02	neutral	0,9	neutral	0,92	neutral	-0,64	0,1	0,36	0,5	neutral	0,11	neutral	0,37	neutral	0,42	neutral	0,44	1	neutral	0	deleterious	1	neutral	-6	neutral	0,13	medium_impact	1,95	high_impact	1,87	medium_impact	-0,29	0,71	0,85	28,32	24,19	N	0,45	N	0,6	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14515	14515	T	A	MI.23857	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	159	53	L	F	ttA/ttT	-0,5	0	0	probably_damaging	1	neutral	0,13	neutral	2,09	deleterious	-4,63	deleterious	-3,94	high_impact	3,64	damaging	0,59	damaging	0,09	deleterious	3,87	23,5	0,37	0,5	disease	0,56	disease	0,89	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,82	low_impact	-3,55	medium_impact	-0,25	medium_impact	1,91	0,76	0,85	11,95	17,19	N	0,34	N	0,95	NA	NA	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14515	14515	T	G	MI.23858	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	159	53	L	F	ttA/ttC	-0,5	0	0	probably_damaging	1	neutral	0,13	neutral	2,09	deleterious	-4,63	deleterious	-3,94	high_impact	3,64	damaging	0,59	damaging	0,09	deleterious	3,63	23,2	0,37	0,5	disease	0,56	disease	0,89	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,82	low_impact	-3,55	medium_impact	-0,25	medium_impact	1,91	0,76	0,85	11,95	17,19	N	0,32	N	0,95	NA	NA	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14516	14516	A	G	MI.23859	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	158	53	L	S	tTa/tCa	-6,01	0	0	probably_damaging	1	neutral	0,07	neutral	1,91	deleterious	-6,14	deleterious	-5,96	high_impact	3,64	damaging	0,5	damaging	0,06	deleterious	3,82	23,4	0,19	0,45	disease	0,81	disease	0,91	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	-0,42	medium_impact	1,91	0,75	0,85	11,95	17,19	N	0,3	N	0,97	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6138	6138	G	A	MI.2386	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	235	79	G	S	Ggc/Agc	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-0,8	deleterious	-4,02	high_impact	4,16	damaging	0,49	damaging	0,02	deleterious	4,08	23,7	0,26	0,55	neutral	0,33	disease	0,89	disease	0,68	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,74	0,7	0,9	1,95	6,64	N	0,4	N	0,73	disease_causing	0,97	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14516	14516	A	C	MI.23860	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	158	53	L	W	tTa/tGa	-6,01	0	0	probably_damaging	1	deleterious	0,04	neutral	1,88	deleterious	-7,79	deleterious	-5,95	high_impact	3,99	damaging	0,41	damaging	0,04	deleterious	3,38	22,9	0,14	0,4	disease	0,9	disease	0,91	disease	0,73	disease	0,83	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,87	low_impact	-3,55	medium_impact	-0,56	high_impact	2,2	0,77	0,85	11,95	17,19	N	0,47	N	0,98	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14517	14517	A	T	MI.23861	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	157	53	L	M	Tta/Ata	4,54	0,25	0	probably_damaging	1	neutral	0,09	neutral	1,98	deleterious	-4,34	neutral	-1,98	medium_impact	3,19	neutral	0,68	damaging	0,17	deleterious	3,19	22,7	0,31	0,45	disease	0,5	disease	0,84	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,77	low_impact	-3,55	medium_impact	-0,35	medium_impact	1,53	0,8	0,85	11,95	17,19	N	0,45	N	0,87	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14517	14517	A	C	MI.23862	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	157	53	L	V	Tta/Gta	4,54	0,25	0	probably_damaging	1	neutral	0,16	neutral	2,05	deleterious	-3,33	deleterious	-2,97	medium_impact	3,19	neutral	0,65	damaging	0,24	deleterious	2,99	22,2	0,31	0,45	neutral	0,38	disease	0,86	disease	0,56	disease	0,56	1	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,79	low_impact	-3,55	medium_impact	-0,19	medium_impact	1,53	0,79	0,85	11,95	17,19	N	0,43	N	0,71	NA	NA	0,68	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14519	14519	C	T	MI.23863	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	155	52	G	D	gGt/gAt	-6,24	0	0	probably_damaging	1	neutral	0,2	neutral	1,85	deleterious	-5,11	deleterious	-6,97	high_impact	3,63	neutral	0,6	damaging	0,05	deleterious	3,97	23,6	0,17	0,45	disease	0,58	disease	0,96	disease	0,67	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	-0,13	medium_impact	1,9	0,73	0,85	12,83	8,79	N	0,28	N	0,96	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14519	14519	C	G	MI.23864	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	155	52	G	A	gGt/gCt	-6,24	0	0	probably_damaging	1	neutral	0,51	neutral	2,11	neutral	-0,91	deleterious	-5,98	medium_impact	2	neutral	0,66	neutral	0,32	deleterious	3,34	22,9	0,39	0,5	neutral	0,31	disease	0,81	neutral	0,37	disease	0,59	2	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,77	low_impact	-3,55	medium_impact	0,22	medium_impact	0,54	0,84	0,9	12,83	8,79	N	0,26	N	0,78	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14519	14519	C	A	MI.23865	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	155	52	G	V	gGt/gTt	-6,24	0	0	probably_damaging	1	neutral	0,5	neutral	1,89	deleterious	-3,18	deleterious	-8,97	high_impact	3,63	damaging	0,55	damaging	0,08	deleterious	4,3	24	0,16	0,45	disease	0,56	disease	0,95	disease	0,6	disease	0,84	7	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	0,21	medium_impact	1,9	0,86	0,9	12,83	8,79	N	0,34	N	0,98	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14520	14520	C	T	MI.23866	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	154	52	G	S	Ggt/Agt	2,71	0,94	0	probably_damaging	1	neutral	0,41	neutral	2,01	neutral	-1,61	deleterious	-5,97	low_impact	1,23	neutral	0,6	neutral	0,4	deleterious	4,32	24	0,34	0,5	neutral	0,11	neutral	0,24	neutral	0,31	neutral	0,42	2	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,64	low_impact	-3,55	medium_impact	0,12	medium_impact	-0,11	0,8	0,85	12,83	8,79	N	0,39	N	1	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14520	14520	C	G	MI.23867	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	154	52	G	R	Ggt/Cgt	2,71	0,94	0	probably_damaging	1	neutral	0,35	neutral	1,86	deleterious	-4,56	deleterious	-7,97	high_impact	3,63	damaging	0,6	damaging	0,04	deleterious	4,14	23,8	0,13	0,4	disease	0,65	disease	0,98	disease	0,69	disease	0,87	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0,06	medium_impact	1,9	0,78	0,85	12,83	8,79	N	0,45	N	1	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14520	14520	C	A	MI.23868	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	154	52	G	C	Ggt/Tgt	2,71	0,94	0	probably_damaging	1	neutral	0,18	neutral	1,85	deleterious	-4,81	deleterious	-8,97	medium_impact	3,08	neutral	0,69	damaging	0,15	deleterious	4,64	24,5	0,15	0,45	disease	0,71	disease	0,95	disease	0,53	disease	0,76	5	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-3,55	medium_impact	-0,16	medium_impact	1,44	0,81	0,85	12,83	8,79	N	0,45	N	0,97	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14521	14521	C	G	MI.23869	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	153	51	M	I	atG/atC	3,17	0,94	0	benign	0,06	neutral	0,37	neutral	2,43	neutral	-1,56	neutral	-0,42	low_impact	1,01	neutral	0,67	neutral	0,67	deleterious	1,91	15,64	0,58	0,65	neutral	0,16	disease	0,75	neutral	0,47	disease	0,58	2	neutral	0,59	deleterious	0,66	neutral	-6	neutral	0,22	medium_impact	0,3	medium_impact	0,08	medium_impact	-0,29	0,72	0,85	20,8	18,4	N	0,43	N	0,62	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6139	6139	G	A	MI.2387	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	236	79	G	D	gGc/gAc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-3,75	deleterious	-4,69	high_impact	5,13	damaging	0,32	damaging	0,01	deleterious	3,71	23,3	0,19	0,55	disease	0,68	disease	0,92	disease	0,78	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,64	0,54	0,9	1,95	6,64	P	0,79	P	0,97	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14521	14521	C	A	MI.23870	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	153	51	M	I	atG/atT	3,17	0,94	0	benign	0,06	neutral	0,37	neutral	2,43	neutral	-1,56	neutral	-0,42	low_impact	1,01	neutral	0,67	neutral	0,67	deleterious	2,32	18,33	0,58	0,65	neutral	0,16	disease	0,75	neutral	0,47	disease	0,58	2	neutral	0,59	deleterious	0,66	neutral	-6	neutral	0,22	medium_impact	0,3	medium_impact	0,08	medium_impact	-0,29	0,72	0,85	20,8	18,4	N	0,43	N	0,62	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14522	14522	A	G	MI.23871	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	152	51	M	T	aTg/aCg	-4,86	0	0	benign	0,14	neutral	0,08	neutral	2,29	deleterious	-3,3	deleterious	-3,3	medium_impact	2,48	damaging	0,54	neutral	0,64	neutral	1,35	12,55	0,49	0,55	neutral	0,43	disease	0,73	disease	0,65	disease	0,73	5	neutral	0,91	deleterious	0,47	neutral	-3	neutral	0,33	medium_impact	-0,07	medium_impact	-0,38	medium_impact	0,94	0,63	0,8	20,8	18,4	N	0,43	N	0,78	NA	NA	0,66	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14522	14522	A	T	MI.23872	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	152	51	M	K	aTg/aAg	-4,86	0	0	benign	0,42	deleterious	0,03	neutral	2,27	deleterious	-4,56	deleterious	-4,23	medium_impact	2,48	damaging	0,54	neutral	0,52	deleterious	3,35	22,9	0,32	0,5	disease	0,62	disease	0,92	disease	0,72	disease	0,84	7	neutral	0,97	neutral	0,31	deleterious	1	deleterious	0,56	medium_impact	-0,67	medium_impact	-0,63	medium_impact	0,94	0,76	0,85	20,8	18,4	N	0,33	N	0,9	NA	NA	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14523	14523	T	A	MI.23873	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	151	51	M	L	Atg/Ttg	8,44	1	0	benign	0	neutral	1	neutral	2,84	neutral	1,6	neutral	1,07	neutral_impact	-0,72	neutral	0,9	neutral	0,98	neutral	-0,98	0,02	0,55	0,6	neutral	0,19	neutral	0,4	neutral	0,43	neutral	0,44	1	neutral	0	deleterious	1	neutral	-6	neutral	0,12	medium_impact	1,95	high_impact	1,87	low_impact	-1,74	0,72	0,85	20,8	18,4	P	0,61	P	0,22	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14523	14523	T	G	MI.23874	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	151	51	M	L	Atg/Ctg	8,44	1	0	benign	0	neutral	1	neutral	2,84	neutral	1,6	neutral	1,07	neutral_impact	-0,72	neutral	0,9	neutral	0,98	neutral	-1,07	0,01	0,55	0,6	neutral	0,19	neutral	0,4	neutral	0,43	neutral	0,44	1	neutral	0	deleterious	1	neutral	-6	neutral	0,12	medium_impact	1,95	high_impact	1,87	low_impact	-1,74	0,72	0,85	20,8	18,4	P	0,61	P	0,22	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14523	14523	T	C	MI.23875	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	151	51	M	V	Atg/Gtg	8,44	1	0	benign	0	neutral	0,23	neutral	2,41	neutral	-1,84	neutral	-1,13	neutral_impact	0,66	neutral	0,79	neutral	0,84	deleterious	0,58	8,05	0,6	0,65	neutral	0,13	disease	0,66	neutral	0,5	neutral	0,44	1	neutral	0,77	deleterious	0,62	neutral	-6	neutral	0,18	medium_impact	1,95	medium_impact	-0,09	medium_impact	-0,59	0,73	0,85	20,8	18,4	P	0,59	P	0,6	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14525	14525	T	C	MI.23876	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	149	50	Y	C	tAt/tGt	1,56	1	0	probably_damaging	0,99	deleterious	0,02	neutral	2,25	deleterious	-4,78	deleterious	-5,26	medium_impact	2,39	neutral	0,76	damaging	0,17	deleterious	3,3	22,8	0,31	0,45	disease	0,82	disease	0,91	disease	0,69	disease	0,83	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,87	low_impact	-2,63	medium_impact	-0,73	medium_impact	0,86	0,35	0,8	17,7	19,1	N	0,4	N	0,77	NA	NA	0,66	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14525	14525	T	A	MI.23877	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	149	50	Y	F	tAt/tTt	1,56	1	0	benign	0,14	neutral	1	neutral	2,77	neutral	2,61	neutral	2,53	neutral_impact	-0,74	neutral	0,86	neutral	0,88	deleterious	0,85	9,76	0,29	0,45	neutral	0,14	neutral	0,31	neutral	0,49	neutral	0,4	2	neutral	0,14	deleterious	0,93	neutral	-6	neutral	0,29	medium_impact	-0,07	high_impact	1,87	low_impact	-1,76	0,56	0,8	17,7	19,1	N	0,38	N	0,25	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14525	14525	T	G	MI.23878	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	149	50	Y	S	tAt/tCt	1,56	1	0	probably_damaging	0,97	neutral	0,38	neutral	2,26	deleterious	-3,21	deleterious	-5,26	medium_impact	2,39	neutral	0,75	damaging	0,21	deleterious	3,88	23,5	0,24	0,45	disease	0,65	disease	0,85	disease	0,64	disease	0,81	6	neutral	0,97	neutral	0,21	deleterious	1	deleterious	0,83	low_impact	-2,18	medium_impact	0,09	medium_impact	0,86	0,4	0,8	17,7	19,1	N	0,43	N	0,81	NA	NA	0,61	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14526	14526	A	G	MI.23879	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	148	50	Y	H	Tat/Cat	5,46	1	0	probably_damaging	0,98	neutral	0,06	neutral	2,24	neutral	-2,75	deleterious	-4,06	medium_impact	2,39	neutral	0,72	damaging	0,2	deleterious	3,53	23,1	0,29	0,45	neutral	0,49	disease	0,81	disease	0,74	disease	0,79	6	deleterious	0,99	neutral	0,04	deleterious	1	deleterious	0,81	low_impact	-2,35	medium_impact	-0,46	medium_impact	0,86	0,62	0,8	17,7	19,1	P	0,56	P	0,72	NA	NA	0,66	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6139	6139	G	C	MI.2388	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	236	79	G	A	gGc/gCc	6,14	1	0	probably_damaging	1	deleterious	0,01	neutral	2,79	neutral	-0,09	deleterious	-4,02	medium_impact	2,96	damaging	0,56	damaging	0,03	deleterious	2,99	22,2	0,32	0,55	neutral	0,33	disease	0,85	disease	0,61	disease	0,54	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,63	0,72	0,9	1,95	6,64	N	0,4	N	0,64	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14526	14526	A	C	MI.23880	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	148	50	Y	D	Tat/Gat	5,46	1	0	probably_damaging	0,98	deleterious	0,02	neutral	2,24	deleterious	-4,47	deleterious	-6,25	medium_impact	2,39	neutral	0,74	damaging	0,18	deleterious	3,51	23,1	0,15	0,4	disease	0,81	disease	0,93	disease	0,73	disease	0,86	7	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,89	low_impact	-2,35	medium_impact	-0,73	medium_impact	0,86	0,38	0,8	17,7	19,1	N	0,53	P	0,92	NA	NA	0,66	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14526	14526	A	T	MI.23881	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	148	50	Y	N	Tat/Aat	5,46	1	0	probably_damaging	0,98	deleterious	0,04	neutral	2,25	deleterious	-3,66	deleterious	-6,19	medium_impact	2,39	neutral	0,72	damaging	0,27	deleterious	3,51	23,1	0,24	0,45	disease	0,68	disease	0,91	disease	0,65	disease	0,82	6	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,86	low_impact	-2,35	medium_impact	-0,56	medium_impact	0,86	0,38	0,8	17,7	19,1	P	0,52	P	0,86	NA	NA	0,66	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14528	14528	C	G	MI.23882	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	146	49	G	A	gGt/gCt	-4,86	0	0	benign	0,01	neutral	0,5	neutral	2,36	neutral	0,54	neutral	0,88	neutral_impact	-0,06	neutral	0,91	neutral	0,77	neutral	1,29	12,24	0,36	0,5	neutral	0,18	disease	0,69	disease	0,54	disease	0,56	1	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,19	medium_impact	1,03	medium_impact	0,21	low_impact	-1,19	0,81	0,85	44,25	12,31	N	0,27	N	0,11	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14528	14528	C	A	MI.23883	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	146	49	G	V	gGt/gTt	-4,86	0	0	benign	0,01	neutral	0,5	neutral	2,35	neutral	-0,97	neutral	-1,8	neutral_impact	0,39	neutral	0,84	neutral	0,74	deleterious	2,26	17,89	0,24	0,45	neutral	0,38	disease	0,87	disease	0,52	disease	0,61	2	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,28	medium_impact	1,03	medium_impact	0,21	medium_impact	-0,81	0,77	0,85	44,25	12,31	N	0,23	N	0,73	NA	NA	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14528	14528	C	T	MI.23884	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	146	49	G	D	gGt/gAt	-4,86	0	0	benign	0,39	neutral	0,2	neutral	2,36	neutral	-1,16	neutral	-0,14	low_impact	1,59	neutral	0,72	neutral	0,43	deleterious	3,59	23,2	0,19	0,45	neutral	0,44	disease	0,89	disease	0,62	disease	0,81	6	neutral	0,76	neutral	0,41	neutral	-6	deleterious	0,52	medium_impact	-0,62	medium_impact	-0,13	medium_impact	0,19	0,67	0,85	44,25	12,31	N	0,36	N	0,64	NA	NA	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14529	14529	C	T	MI.23885	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	145	49	G	S	Ggt/Agt	1,56	0,06	0	benign	0,02	neutral	0,41	neutral	2,5	neutral	3,1	neutral	3,52	neutral_impact	-1,94	neutral	0,87	neutral	0,87	neutral	-0,11	1,67	0,4	0,5	neutral	0,15	neutral	0,16	neutral	0,31	neutral	0,24	5	neutral	0,57	deleterious	0,7	neutral	-6	neutral	0,1	medium_impact	0,75	medium_impact	0,12	low_impact	-2,77	0,87	0,9	44,25	12,31	N	0,32	N	0,3	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14529	14529	C	G	MI.23886	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	145	49	G	R	Ggt/Cgt	1,56	0,06	0	possibly_damaging	0,6	neutral	0,34	neutral	2,31	neutral	-1,29	neutral	-0,99	low_impact	1,59	neutral	0,8	neutral	0,44	deleterious	3,93	23,5	0,22	0,45	neutral	0,46	disease	0,94	disease	0,63	disease	0,87	7	neutral	0,68	neutral	0,37	neutral	-3	deleterious	0,72	medium_impact	-0,96	medium_impact	0,05	medium_impact	0,19	0,89	0,9	44,25	12,31	N	0,29	N	0,69	NA	NA	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14529	14529	C	A	MI.23887	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	145	49	G	C	Ggt/Tgt	1,56	0,06	0	possibly_damaging	0,87	neutral	0,18	neutral	2,28	neutral	-2,43	neutral	-1,11	low_impact	0,9	neutral	0,78	neutral	0,54	deleterious	4,53	24,3	0,19	0,45	disease	0,56	disease	0,88	neutral	0,5	disease	0,75	5	neutral	0,93	neutral	0,16	neutral	-3	deleterious	0,75	low_impact	-1,55	medium_impact	-0,16	medium_impact	-0,39	0,81	0,85	44,25	12,31	N	0,34	N	0,64	NA	NA	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14531	14531	C	T	MI.23888	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	143	48	G	E	gGa/gAa	-12,43	0	0	probably_damaging	1	neutral	0,27	neutral	2,34	neutral	-1,37	deleterious	-7,99	medium_impact	3,02	neutral	0,72	damaging	0,09	deleterious	2,49	19,39	0,26	0,45	disease	0,6	disease	0,96	disease	0,8	disease	0,92	8	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,85	low_impact	-3,55	medium_impact	-0,03	medium_impact	1,39	0,69	0,85	19,47	20,58	N	0,38	N	0,95	NA	NA	0,61	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14531	14531	C	A	MI.23889	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	143	48	G	V	gGa/gTa	-12,43	0	0	probably_damaging	1	neutral	0,5	neutral	2,32	neutral	-2,16	deleterious	-8,98	medium_impact	2,02	neutral	0,74	damaging	0,22	deleterious	4,1	23,7	0,25	0,45	neutral	0,34	disease	0,88	disease	0,58	disease	0,59	2	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,79	low_impact	-3,55	medium_impact	0,21	medium_impact	0,55	0,81	0,85	19,47	20,58	N	0,3	N	0,98	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6139	6139	G	T	MI.2389	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	236	79	G	V	gGc/gTc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,63	neutral	-1,51	deleterious	-6,03	high_impact	4,78	damaging	0,47	damaging	0,02	deleterious	3,67	23,2	0,18	0,55	disease	0,51	disease	0,95	disease	0,7	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,32	0,62	0,9	1,95	6,64	P	0,66	P	0,93	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14531	14531	C	G	MI.23890	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	143	48	G	A	gGa/gCa	-12,43	0	0	probably_damaging	1	neutral	0,51	neutral	2,42	neutral	-1,53	deleterious	-5,99	medium_impact	2,42	neutral	0,78	neutral	0,53	deleterious	3,23	22,8	0,31	0,5	neutral	0,33	disease	0,86	disease	0,54	disease	0,58	2	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,78	low_impact	-3,55	medium_impact	0,22	medium_impact	0,89	0,72	0,85	19,47	20,58	N	0,28	N	0,72	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14532	14532	C	G	MI.23891	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	142	48	G	R	Gga/Cga	0,41	0	0	probably_damaging	1	neutral	0,35	neutral	2,32	neutral	-1,83	deleterious	-7,99	high_impact	3,7	neutral	0,68	damaging	0,06	deleterious	4,08	23,7	0,19	0,45	disease	0,66	disease	0,97	disease	0,8	disease	0,92	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	0,06	medium_impact	1,96	0,85	0,9	19,47	20,58	N	0,43	N	0,96	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14532	14532	C	A	MI.23892	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	142	48	G	W	Gga/Tga	0,41	0	0	probably_damaging	1	neutral	0,19	neutral	2,28	neutral	-0,89	deleterious	-7,99	medium_impact	3,36	neutral	0,75	damaging	0,08	deleterious	4,74	24,6	0,21	0,45	disease	0,92	disease	0,96	disease	0,73	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,88	low_impact	-3,55	medium_impact	-0,14	medium_impact	1,68	0,61	0,8	19,47	20,58	N	0,37	N	0,97	NA	NA	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14534	14534	C	G	MI.23893	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	140	47	G	A	gGg/gCg	-7,38	0	0	probably_damaging	1	neutral	0,5	neutral	2,08	deleterious	-3,22	deleterious	-5,79	high_impact	3,96	damaging	0,46	damaging	0,09	deleterious	3,21	22,7	0,28	0,45	disease	0,71	disease	0,95	disease	0,81	disease	0,91	8	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	0,21	high_impact	2,18	0,48	0,8	22,12	21,76	N	0,48	N	0,74	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14534	14534	C	A	MI.23894	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	140	47	G	V	gGg/gTg	-7,38	0	0	probably_damaging	1	neutral	0,5	neutral	2,06	deleterious	-4,54	deleterious	-8,74	high_impact	3,96	damaging	0,34	damaging	0,05	deleterious	4,11	23,7	0,18	0,45	disease	0,87	disease	0,98	disease	0,82	disease	0,91	8	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,91	low_impact	-3,55	medium_impact	0,21	high_impact	2,18	0,64	0,8	22,12	21,76	P	0,6	P	0,98	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14534	14534	C	T	MI.23895	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	140	47	G	E	gGg/gAg	-7,38	0	0	probably_damaging	1	neutral	0,27	neutral	2,09	neutral	-2,61	deleterious	-7,69	medium_impact	2,49	neutral	0,62	neutral	0,51	deleterious	2,42	18,97	0,24	0,45	disease	0,84	disease	0,97	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,9	low_impact	-3,55	medium_impact	-0,03	medium_impact	0,95	0,55	0,8	22,12	21,76	N	0,38	N	0,79	NA	NA	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14535	14535	C	G	MI.23896	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	139	47	G	R	Ggg/Cgg	2,71	0,66	0	probably_damaging	1	neutral	0,34	neutral	2,04	deleterious	-4,18	deleterious	-7,7	high_impact	3,96	damaging	0,37	damaging	0,04	deleterious	4,01	23,6	0,17	0,45	disease	0,88	disease	0,98	disease	0,83	disease	0,91	8	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	0,05	high_impact	2,18	0,67	0,85	22,12	21,76	P	0,71	P	0,96	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14535	14535	C	A	MI.23897	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	139	47	G	W	Ggg/Tgg	2,71	0,66	0	probably_damaging	1	neutral	0,2	neutral	2	deleterious	-7,78	deleterious	-7,82	high_impact	3,96	damaging	0,43	damaging	0,04	deleterious	4,75	24,7	0,16	0,45	disease	0,97	disease	0,98	disease	0,83	disease	0,86	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	-0,13	high_impact	2,18	0,45	0,8	22,12	21,76	P	0,58	P	0,98	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14536	14536	A	T	MI.23898	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	138	46	F	L	ttT/ttA	2,02	0,66	0	benign	0	neutral	0,71	neutral	2,79	neutral	0,03	deleterious	-4,3	neutral_impact	0,36	neutral	0,87	neutral	0,93	deleterious	0,68	8,66	0,45	0,55	neutral	0,27	disease	0,59	neutral	0,44	neutral	0,46	1	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,18	medium_impact	1,95	medium_impact	0,42	medium_impact	-0,84	0,64	0,8	49,56	8,75	N	0,34	N	0,54	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14536	14536	A	C	MI.23899	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	138	46	F	L	ttT/ttG	2,02	0,66	0	benign	0	neutral	0,71	neutral	2,79	neutral	0,03	deleterious	-4,3	neutral_impact	0,36	neutral	0,87	neutral	0,93	deleterious	0,47	7,18	0,45	0,55	neutral	0,27	disease	0,59	neutral	0,44	neutral	0,46	1	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,18	medium_impact	1,95	medium_impact	0,42	medium_impact	-0,84	0,64	0,8	49,56	8,75	N	0,32	N	0,54	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8639	8639	T	G	MI.239	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	113	38	I	S	aTc/aGc	-3,8	0	0	probably_damaging	0,99	neutral	0,42	neutral	4,27	neutral	-1,65	deleterious	-3,84	low_impact	1,36	neutral	0,89	neutral	0,57	deleterious	4,08	23,7	0,44	0,65	disease	0,63	disease	0,68	neutral	0,42	disease	0,57	1	deleterious	0,99	neutral	0,22	neutral	-2	deleterious	0,77	low_impact	-2,65	medium_impact	0,21	medium_impact	0,07	0,38	0,9	15,49	18,25	N	0,3	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6141	6141	A	T	MI.2390	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	238	80	N	Y	Aac/Tac	-8,9	0	0	probably_damaging	1	deleterious	0	neutral	2,83	neutral	-0,98	deleterious	-5,45	high_impact	4,86	damaging	0,55	damaging	0,12	deleterious	3,68	23,3	0,27	0,55	disease	0,66	disease	0,92	disease	0,72	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,39	0,49	0,9	2,34	6,63	P	0,62	P	0,93	polymorphism	0,88	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14537	14537	A	C	MI.23900	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	137	46	F	C	tTt/tGt	-0,96	0	0	benign	0	neutral	0,19	neutral	2,28	deleterious	-4,5	deleterious	-6,16	low_impact	1,33	neutral	0,92	neutral	0,93	deleterious	0,45	7,03	0,24	0,45	disease	0,83	disease	0,9	disease	0,55	disease	0,69	4	neutral	0,81	deleterious	0,6	neutral	-6	neutral	0,31	medium_impact	1,95	medium_impact	-0,14	medium_impact	-0,03	0,52	0,8	49,56	8,75	N	0,42	N	0,02	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14537	14537	A	T	MI.23901	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	137	46	F	Y	tTt/tAt	-0,96	0	0	benign	0	neutral	1	neutral	2,31	neutral	-0,56	neutral	-1,92	low_impact	1,12	neutral	0,95	neutral	0,97	deleterious	0,22	4,93	0,42	0,5	neutral	0,2	disease	0,75	neutral	0,48	disease	0,58	2	neutral	0	deleterious	1	neutral	-6	neutral	0,19	medium_impact	1,95	high_impact	1,87	medium_impact	-0,2	0,61	0,8	49,56	8,75	N	0,34	N	0,02	NA	NA	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14537	14537	A	G	MI.23902	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	137	46	F	S	tTt/tCt	-0,96	0	0	benign	0,14	neutral	0,46	neutral	2,3	neutral	-2,83	deleterious	-6,05	low_impact	1,69	neutral	0,83	neutral	0,97	neutral	1,21	11,82	0,41	0,5	disease	0,66	disease	0,83	disease	0,57	disease	0,65	3	neutral	0,46	deleterious	0,66	neutral	-6	neutral	0,42	medium_impact	-0,07	medium_impact	0,17	medium_impact	0,28	0,68	0,85	49,56	8,75	N	0,31	N	0,48	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14538	14538	A	C	MI.23903	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	136	46	F	V	Ttt/Gtt	-0,27	0	0	benign	0,09	neutral	0,52	neutral	2,36	neutral	-1,99	deleterious	-5,31	low_impact	1,92	neutral	0,74	neutral	0,63	neutral	1,74	14,64	0,36	0,5	disease	0,55	disease	0,9	disease	0,63	disease	0,65	3	neutral	0,4	deleterious	0,72	neutral	-6	neutral	0,32	medium_impact	0,13	medium_impact	0,23	medium_impact	0,47	0,73	0,85	49,56	8,75	N	0,29	N	0,52	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14538	14538	A	G	MI.23904	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	136	46	F	L	Ttt/Ctt	-0,27	0	0	benign	0	neutral	0,71	neutral	2,79	neutral	0,03	deleterious	-4,3	neutral_impact	0,36	neutral	0,87	neutral	0,93	deleterious	0,61	8,25	0,45	0,55	neutral	0,27	disease	0,59	neutral	0,44	neutral	0,46	1	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,18	medium_impact	1,95	medium_impact	0,42	medium_impact	-0,84	0,64	0,8	49,56	8,75	N	0,3	N	0,54	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14538	14538	A	T	MI.23905	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	136	46	F	I	Ttt/Att	-0,27	0	0	benign	0,09	neutral	0,42	neutral	2,36	neutral	-2,22	deleterious	-4,52	medium_impact	2,52	neutral	0,72	neutral	0,52	deleterious	1,99	16,17	0,25	0,45	disease	0,58	disease	0,84	disease	0,62	disease	0,79	6	neutral	0,52	deleterious	0,67	neutral	-3	neutral	0,32	medium_impact	0,13	medium_impact	0,13	medium_impact	0,97	0,68	0,85	49,56	8,75	N	0,31	N	0,49	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14539	14539	A	C	MI.23906	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	135	45	N	K	aaT/aaG	0,64	0	0	benign	0,14	neutral	0,3	neutral	2,34	neutral	0,96	neutral	-2,29	low_impact	1,63	neutral	0,75	neutral	0,51	deleterious	0,53	7,63	0,62	0,65	neutral	0,22	disease	0,82	disease	0,62	disease	0,77	5	neutral	0,65	deleterious	0,58	neutral	-6	neutral	0,29	medium_impact	-0,07	medium_impact	0	medium_impact	0,23	0,73	0,85	18,14	18,2	N	0,43	N	0,74	NA	NA	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14539	14539	A	T	MI.23907	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	135	45	N	K	aaT/aaA	0,64	0	0	benign	0,14	neutral	0,3	neutral	2,34	neutral	0,96	neutral	-2,29	low_impact	1,63	neutral	0,75	neutral	0,51	deleterious	0,59	8,08	0,62	0,65	neutral	0,22	disease	0,82	disease	0,62	disease	0,77	5	neutral	0,65	deleterious	0,58	neutral	-6	neutral	0,29	medium_impact	-0,07	medium_impact	0	medium_impact	0,23	0,73	0,85	18,14	18,2	N	0,38	N	0,74	NA	NA	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14540	14540	T	C	MI.23908	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	134	45	N	S	aAt/aGt	-1,65	0	0	benign	0,01	neutral	0,41	neutral	2,4	neutral	2,22	neutral	0,32	neutral_impact	-0,2	neutral	0,91	neutral	0,98	neutral	-1,82	0	0,66	0,7	neutral	0,12	neutral	0,25	neutral	0,37	neutral	0,41	2	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,12	low_impact	-1,31	0,39	0,8	18,14	18,2	N	0,39	N	0,09	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14540	14540	T	G	MI.23909	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	134	45	N	T	aAt/aCt	-1,65	0	0	benign	0,14	neutral	0,39	neutral	2,38	neutral	2	neutral	-1,76	low_impact	1,74	neutral	0,75	neutral	0,66	deleterious	0,73	9,04	0,49	0,55	neutral	0,26	disease	0,63	disease	0,51	disease	0,59	2	neutral	0,54	deleterious	0,63	neutral	-6	neutral	0,24	medium_impact	-0,07	medium_impact	0,1	medium_impact	0,32	0,64	0,8	18,14	18,2	N	0,4	N	0,47	NA	NA	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6141	6141	A	G	MI.2391	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	238	80	N	D	Aac/Gac	-8,9	0	0	probably_damaging	1	deleterious	0	neutral	2,66	deleterious	-4,24	deleterious	-3,4	high_impact	5,2	damaging	0,52	damaging	0,15	deleterious	3,78	23,4	0,6	0,65	disease	0,85	disease	0,83	disease	0,77	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,7	0,68	0,9	2,34	6,63	P	0,67	P	0,92	polymorphism	0,98	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14540	14540	T	A	MI.23910	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	134	45	N	I	aAt/aTt	-1,65	0	0	possibly_damaging	0,48	neutral	0,4	neutral	2,42	neutral	2,5	deleterious	-4,25	low_impact	1,88	neutral	0,73	neutral	0,57	deleterious	2,34	18,44	0,34	0,5	neutral	0,41	disease	0,8	disease	0,51	disease	0,71	4	neutral	0,57	neutral	0,46	neutral	-3	neutral	0,42	medium_impact	-0,76	medium_impact	0,11	medium_impact	0,44	0,56	0,8	18,14	18,2	N	0,34	N	0,86	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14541	14541	T	G	MI.23911	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	133	45	N	H	Aat/Cat	-2,34	0	0	possibly_damaging	0,52	neutral	0,54	neutral	2,31	neutral	-0,89	neutral	-2,3	medium_impact	2,44	neutral	0,73	neutral	0,52	deleterious	2,06	16,62	0,47	0,55	neutral	0,45	disease	0,65	disease	0,62	disease	0,75	5	neutral	0,49	deleterious	0,51	NA	0	deleterious	0,49	medium_impact	-0,83	medium_impact	0,25	medium_impact	0,9	0,74	0,85	18,14	18,2	N	0,26	N	0,5	NA	NA	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14541	14541	T	C	MI.23912	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	133	45	N	D	Aat/Gat	-2,34	0	0	benign	0,01	neutral	0,21	neutral	2,31	neutral	-1,46	neutral	-1,92	low_impact	1,15	neutral	0,82	neutral	0,6	deleterious	0,12	3,82	0,63	0,7	neutral	0,29	disease	0,62	neutral	0,5	neutral	0,45	1	neutral	0,79	deleterious	0,6	neutral	-6	neutral	0,19	medium_impact	1,03	medium_impact	-0,11	medium_impact	-0,18	0,65	0,8	18,14	18,2	N	0,44	N	0,68	NA	NA	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14541	14541	T	A	MI.23913	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	133	45	N	Y	Aat/Tat	-2,34	0	0	benign	0	neutral	1	neutral	2,35	neutral	1,18	deleterious	-3,36	neutral_impact	0,48	neutral	0,93	neutral	0,78	deleterious	2,65	20,5	0,36	0,5	disease	0,52	disease	0,8	neutral	0,42	disease	0,61	2	neutral	0	deleterious	1	neutral	-6	neutral	0,27	medium_impact	1,95	high_impact	1,87	medium_impact	-0,74	0,69	0,85	18,14	18,2	N	0,25	N	0,88	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14543	14543	A	C	MI.23914	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	131	44	L	R	cTg/cGg	-4,4	0	0	probably_damaging	0,99	neutral	0,09	neutral	1,96	deleterious	-3,51	deleterious	-4,74	medium_impact	3,23	neutral	0,6	neutral	0,42	deleterious	3,74	23,3	0,18	0,45	disease	0,77	disease	0,94	disease	0,71	disease	0,88	8	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,89	low_impact	-2,63	medium_impact	-0,35	medium_impact	1,57	0,84	0,9	21,24	19,09	N	0,31	N	0,94	NA	NA	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14543	14543	A	G	MI.23915	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	131	44	L	P	cTg/cCg	-4,4	0	0	probably_damaging	0,99	neutral	0,05	neutral	1,95	deleterious	-4,25	deleterious	-5,18	medium_impact	3,23	neutral	0,61	neutral	0,35	deleterious	3,91	23,5	0,15	0,45	disease	0,81	disease	0,95	disease	0,59	disease	0,84	7	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,89	low_impact	-2,63	medium_impact	-0,5	medium_impact	1,57	0,68	0,85	21,24	19,09	N	0,31	N	0,9	NA	NA	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14543	14543	A	T	MI.23916	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	131	44	L	Q	cTg/cAg	-4,4	0	0	probably_damaging	0,99	neutral	0,08	neutral	1,95	deleterious	-3,59	deleterious	-4,26	medium_impact	3,23	neutral	0,61	neutral	0,5	deleterious	3,64	23,2	0,23	0,45	disease	0,77	disease	0,82	disease	0,59	disease	0,78	6	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,84	low_impact	-2,63	medium_impact	-0,38	medium_impact	1,57	0,87	0,9	21,24	19,09	N	0,34	N	0,94	NA	NA	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14544	14544	G	C	MI.23917	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	130	44	L	V	Ctg/Gtg	5,92	0,56	0	benign	0,36	neutral	1	neutral	2,03	neutral	0,62	neutral	-0,81	neutral_impact	0,52	neutral	0,83	neutral	0,96	neutral	1,39	12,74	0,52	0,6	neutral	0,12	neutral	0,18	neutral	0,26	neutral	0,25	5	neutral	0,36	deleterious	0,82	neutral	-6	neutral	0,42	medium_impact	-0,57	high_impact	1,87	medium_impact	-0,7	0,87	0,9	21,24	19,09	N	0,44	N	0,44	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14544	14544	G	T	MI.23918	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	130	44	L	M	Ctg/Atg	5,92	0,56	0	probably_damaging	0,98	neutral	0,34	neutral	2,01	neutral	-2,71	neutral	-0,3	low_impact	1,52	neutral	0,84	neutral	0,96	neutral	1,67	14,24	0,33	0,5	neutral	0,37	neutral	0,5	neutral	0,33	neutral	0,48	0	deleterious	0,99	neutral	0,18	neutral	-2	deleterious	0,71	low_impact	-2,35	medium_impact	0,05	medium_impact	0,13	0,74	0,85	21,24	19,09	N	0,45	N	0,65	NA	NA	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14545	14545	A	T	MI.23919	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	129	43	I	M	atT/atA	-0,96	0	0	benign	0,06	neutral	0,27	neutral	2,28	neutral	-0,38	neutral	-2,21	low_impact	1,5	neutral	0,85	neutral	0,6	neutral	1,14	11,41	0,37	0,5	neutral	0,42	disease	0,68	disease	0,51	disease	0,58	2	neutral	0,7	deleterious	0,61	neutral	-6	neutral	0,24	medium_impact	0,3	medium_impact	-0,03	medium_impact	0,12	0,86	0,9	31,42	20,88	N	0,37	N	0,68	NA	NA	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6141	6141	A	C	MI.2392	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	238	80	N	H	Aac/Cac	-8,9	0	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-3,83	deleterious	-3,4	high_impact	5,2	damaging	0,57	damaging	0,12	deleterious	3,06	22,4	0,4	0,55	disease	0,85	disease	0,87	disease	0,77	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,7	0,48	0,9	2,34	6,63	P	0,69	P	0,83	polymorphism	0,97	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14545	14545	A	C	MI.23920	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	129	43	I	M	atT/atG	-0,96	0	0	benign	0,06	neutral	0,27	neutral	2,28	neutral	-0,38	neutral	-2,21	low_impact	1,5	neutral	0,85	neutral	0,6	neutral	1,08	11,11	0,37	0,5	neutral	0,42	disease	0,68	disease	0,51	disease	0,58	2	neutral	0,7	deleterious	0,61	neutral	-6	neutral	0,24	medium_impact	0,3	medium_impact	-0,03	medium_impact	0,12	0,86	0,9	31,42	20,88	N	0,41	N	0,68	NA	NA	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14546	14546	A	G	MI.23921	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	128	43	I	T	aTt/aCt	-4,86	0	0	benign	0,01	neutral	0,12	neutral	2,21	neutral	-1,64	deleterious	-3,34	low_impact	1,44	neutral	0,75	neutral	0,37	deleterious	2,98	22,2	0,42	0,55	neutral	0,38	disease	0,76	disease	0,58	disease	0,74	5	neutral	0,88	deleterious	0,56	neutral	-6	neutral	0,24	medium_impact	1,03	medium_impact	-0,27	medium_impact	0,07	0,82	0,85	31,42	20,88	N	0,37	N	0,82	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14546	14546	A	C	MI.23922	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	128	43	I	S	aTt/aGt	-4,86	0	0	benign	0,22	neutral	0,24	neutral	2,2	neutral	-1,72	deleterious	-5,08	medium_impact	2,54	neutral	0,7	neutral	0,51	deleterious	3,68	23,3	0,28	0,45	neutral	0,26	disease	0,88	disease	0,6	disease	0,82	6	neutral	0,71	deleterious	0,51	neutral	-3	neutral	0,36	medium_impact	-0,29	medium_impact	-0,07	medium_impact	0,99	0,76	0,85	31,42	20,88	N	0,44	N	0,91	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14546	14546	A	T	MI.23923	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	128	43	I	N	aTt/aAt	-4,86	0	0	possibly_damaging	0,6	neutral	0,11	neutral	2,16	deleterious	-3,73	deleterious	-6,08	medium_impact	2,54	neutral	0,69	neutral	0,4	deleterious	3,89	23,5	0,32	0,5	disease	0,62	disease	0,9	disease	0,63	disease	0,82	6	neutral	0,89	neutral	0,26	NA	0	deleterious	0,6	medium_impact	-0,96	medium_impact	-0,3	medium_impact	0,99	0,71	0,85	31,42	20,88	N	0,39	N	0,96	NA	NA	0,62	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14547	14547	T	A	MI.23924	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	127	43	I	F	Att/Ttt	1,79	0	0	possibly_damaging	0,52	neutral	0,25	neutral	2,33	neutral	0,06	deleterious	-3,89	medium_impact	2,54	neutral	0,72	neutral	0,43	deleterious	3,86	23,4	0,32	0,5	neutral	0,44	disease	0,88	disease	0,63	disease	0,82	6	neutral	0,73	neutral	0,37	NA	0	deleterious	0,56	medium_impact	-0,83	medium_impact	-0,06	medium_impact	0,99	0,86	0,9	31,42	20,88	N	0,36	N	0,83	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14547	14547	T	G	MI.23925	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	127	43	I	L	Att/Ctt	1,79	0	0	benign	0,06	neutral	1	neutral	2,44	neutral	0,79	neutral	-1,92	neutral_impact	-0,3	neutral	0,75	neutral	0,76	deleterious	2	16,2	0,31	0,5	neutral	0,14	neutral	0,32	neutral	0,34	neutral	0,43	1	neutral	0,06	deleterious	0,97	neutral	-6	neutral	0,16	medium_impact	0,3	high_impact	1,87	low_impact	-1,39	0,77	0,85	31,42	20,88	N	0,31	N	0,64	NA	NA	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14547	14547	T	C	MI.23926	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	127	43	I	V	Att/Gtt	1,79	0	0	benign	0,01	neutral	0,21	neutral	2,27	neutral	-0,57	neutral	0,39	neutral_impact	-0,3	neutral	0,92	neutral	0,97	neutral	-1,87	0	0,39	0,5	neutral	0,1	neutral	0,45	neutral	0,35	neutral	0,42	2	neutral	0,79	deleterious	0,6	neutral	-6	neutral	0,11	medium_impact	1,03	medium_impact	-0,11	low_impact	-1,39	0,7	0,85	31,42	20,88	N	0,48	N	0,04	NA	NA	0,18	.	.	.	.	.	.	COSM1138270	.	.	.	.	.	.	.	.
chrM	14548	14548	A	T	MI.23927	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	126	42	I	M	atT/atA	-0,04	0	0	possibly_damaging	0,73	neutral	0,22	neutral	1,99	neutral	-2,75	neutral	-2,06	low_impact	1,74	neutral	0,85	neutral	0,91	neutral	-0,25	0,88	0,36	0,5	neutral	0,23	disease	0,61	neutral	0,42	neutral	0,47	1	neutral	0,84	neutral	0,25	neutral	-3	deleterious	0,58	low_impact	-1,19	medium_impact	-0,1	medium_impact	0,32	0,86	0,9	25,22	18,79	N	0,4	N	0,36	NA	NA	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14548	14548	A	C	MI.23928	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	126	42	I	M	atT/atG	-0,04	0	0	possibly_damaging	0,73	neutral	0,22	neutral	1,99	neutral	-2,75	neutral	-2,06	low_impact	1,74	neutral	0,85	neutral	0,91	neutral	-0,3	0,65	0,36	0,5	neutral	0,23	disease	0,61	neutral	0,42	neutral	0,47	1	neutral	0,84	neutral	0,25	neutral	-3	deleterious	0,58	low_impact	-1,19	medium_impact	-0,1	medium_impact	0,32	0,86	0,9	25,22	18,79	N	0,39	N	0,36	NA	NA	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14549	14549	A	T	MI.23929	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	125	42	I	N	aTt/aAt	-1,65	0	0	possibly_damaging	0,88	neutral	0,31	neutral	1,95	deleterious	-4,38	deleterious	-6,25	medium_impact	3,35	neutral	0,8	neutral	0,42	deleterious	3,81	23,4	0,34	0,5	disease	0,54	disease	0,89	disease	0,67	disease	0,8	6	neutral	0,9	neutral	0,22	NA	0	deleterious	0,77	low_impact	-1,59	medium_impact	0,01	medium_impact	1,67	0,61	0,8	25,22	18,79	N	0,3	N	0,81	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6142	6142	A	C	MI.2393	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	239	80	N	T	aAc/aCc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-2,44	deleterious	-4,08	high_impact	4,86	damaging	0,58	damaging	0,13	deleterious	3,29	22,8	0,44	0,55	disease	0,78	disease	0,89	disease	0,7	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,39	0,55	0,9	2,34	6,63	P	0,74	P	0,59	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14549	14549	A	G	MI.23930	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	125	42	I	T	aTt/aCt	-1,65	0	0	possibly_damaging	0,46	neutral	0,39	neutral	1,99	neutral	-2,81	deleterious	-4,23	medium_impact	3	neutral	0,66	neutral	0,35	neutral	1,69	14,33	0,39	0,5	neutral	0,32	disease	0,8	disease	0,6	disease	0,73	5	neutral	0,57	neutral	0,47	NA	0	deleterious	0,47	medium_impact	-0,73	medium_impact	0,1	medium_impact	1,37	0,76	0,85	25,22	18,79	N	0,33	N	0,66	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14549	14549	A	C	MI.23931	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	125	42	I	S	aTt/aGt	-1,65	0	0	possibly_damaging	0,73	neutral	0,4	neutral	2	neutral	-2,61	deleterious	-5,18	medium_impact	3,35	neutral	0,67	neutral	0,38	deleterious	2,27	17,94	0,3	0,45	neutral	0,37	disease	0,91	disease	0,63	disease	0,8	6	neutral	0,74	neutral	0,34	NA	0	deleterious	0,68	low_impact	-1,19	medium_impact	0,11	medium_impact	1,67	0,71	0,85	25,22	18,79	N	0,43	N	0,75	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14550	14550	T	C	MI.23932	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	124	42	I	V	Att/Gtt	2,71	0,01	0	benign	0,02	neutral	0,5	neutral	2,12	neutral	-1,18	neutral	-0,67	neutral_impact	0,62	neutral	0,92	neutral	0,9	neutral	-0,45	0,29	0,34	0,5	neutral	0,15	neutral	0,26	neutral	0,33	neutral	0,43	2	neutral	0,48	deleterious	0,74	neutral	-6	neutral	0,12	medium_impact	0,75	medium_impact	0,21	medium_impact	-0,62	0,7	0,85	25,22	18,79	N	0,41	N	0,07	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14550	14550	T	A	MI.23933	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	124	42	I	F	Att/Ttt	2,71	0,01	0	possibly_damaging	0,66	neutral	0,7	neutral	2,05	neutral	-1,8	deleterious	-3,52	medium_impact	2,44	neutral	0,71	neutral	0,51	deleterious	2,4	18,83	0,33	0,5	neutral	0,36	disease	0,89	disease	0,59	disease	0,76	5	neutral	0,59	deleterious	0,52	NA	0	deleterious	0,65	low_impact	-1,06	medium_impact	0,41	medium_impact	0,9	0,83	0,9	25,22	18,79	N	0,38	N	0,53	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14550	14550	T	G	MI.23934	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	124	42	I	L	Att/Ctt	2,71	0,01	0	benign	0,02	neutral	0,65	neutral	2,2	neutral	-0,62	neutral	-1,4	low_impact	0,95	neutral	0,82	neutral	0,92	deleterious	0,6	8,17	0,28	0,45	neutral	0,18	disease	0,65	neutral	0,38	neutral	0,46	1	neutral	0,32	deleterious	0,82	neutral	-6	neutral	0,17	medium_impact	0,75	medium_impact	0,36	medium_impact	-0,34	0,7	0,85	25,22	18,79	N	0,39	N	0,34	NA	NA	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14552	14552	A	C	MI.23935	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	122	41	V	G	gTt/gGt	-10,6	0	0,02	benign	0	neutral	0,4	neutral	2,3	neutral	-2,87	neutral	4,35	neutral_impact	-0,69	neutral	0,82	neutral	0,96	neutral	-1,32	0	0,3	0,45	neutral	0,09	neutral	0,2	neutral	0,36	neutral	0,31	4	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	1,95	medium_impact	0,11	low_impact	-1,72	0,65	0,8	44,69	8,36	N	0,36	N	0,08	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14552	14552	A	G	MI.23936	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	122	41	V	A	gTt/gCt	-10,6	0	0,02	benign	0	neutral	0,52	neutral	2,36	neutral	-1,65	neutral	1,58	neutral_impact	-0,04	neutral	0,96	neutral	0,98	deleterious	0,18	4,42	0,4	0,5	neutral	0,17	disease	0,54	neutral	0,39	neutral	0,44	1	neutral	0,47	deleterious	0,76	neutral	-6	neutral	0,18	medium_impact	1,95	medium_impact	0,23	low_impact	-1,17	0,76	0,85	44,69	8,36	N	0,28	N	0,01	NA	NA	0,18	.	.	.	.	.	pancreatic cancer cell line	.	.	.	.	.	.	.	.	.
chrM	14552	14552	A	T	MI.23937	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	122	41	V	D	gTt/gAt	-10,6	0	0,02	benign	0,28	neutral	0,2	neutral	2,17	deleterious	-3,49	neutral	-0,09	medium_impact	2,19	neutral	0,67	neutral	0,49	deleterious	2,17	17,3	0,17	0,45	neutral	0,47	disease	0,87	disease	0,62	disease	0,82	6	neutral	0,76	neutral	0,46	neutral	-3	deleterious	0,44	medium_impact	-0,42	medium_impact	-0,13	medium_impact	0,7	0,71	0,85	44,69	8,36	N	0,44	N	0,53	NA	NA	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14553	14553	C	A	MI.23938	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	121	41	V	F	Gtt/Ttt	-0,73	0	0	benign	0,22	neutral	0,7	neutral	2,4	deleterious	-3,95	neutral	-0,69	low_impact	1,38	neutral	0,81	neutral	0,73	neutral	1,14	11,43	0,21	0,45	neutral	0,34	disease	0,87	neutral	0,35	disease	0,74	5	neutral	0,19	deleterious	0,74	neutral	-6	deleterious	0,49	medium_impact	-0,29	medium_impact	0,41	medium_impact	0,02	0,69	0,85	44,69	8,36	N	0,25	N	0,39	NA	NA	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14553	14553	C	T	MI.23939	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	121	41	V	I	Gtt/Att	-0,73	0	0	benign	0	neutral	0,41	neutral	2,28	neutral	-2,88	neutral	-0,65	low_impact	1,38	neutral	0,74	neutral	0,6	deleterious	0,44	6,95	0,5	0,6	neutral	0,17	neutral	0,46	neutral	0,47	neutral	0,48	0	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,16	medium_impact	1,95	medium_impact	0,12	medium_impact	0,02	0,75	0,85	44,69	8,36	N	0,44	N	0,25	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6142	6142	A	T	MI.2394	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	239	80	N	I	aAc/aTc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,77	neutral	-1,59	deleterious	-6,13	high_impact	4,65	damaging	0,57	damaging	0,12	deleterious	3,86	23,5	0,27	0,55	disease	0,58	disease	0,95	disease	0,61	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,2	0,43	0,9	2,34	6,63	P	0,53	P	0,98	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14553	14553	C	G	MI.23940	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	121	41	V	L	Gtt/Ctt	-0,73	0	0	benign	0,03	neutral	0,67	neutral	2,43	neutral	-2,57	neutral	-0,64	neutral_impact	0,56	neutral	0,86	neutral	0,92	neutral	-0,28	0,74	0,4	0,5	neutral	0,1	disease	0,6	neutral	0,31	neutral	0,43	1	neutral	0,28	deleterious	0,82	neutral	-6	neutral	0,17	medium_impact	0,59	medium_impact	0,38	medium_impact	-0,67	0,87	0,9	44,69	8,36	N	0,28	N	0,21	NA	NA	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14554	14554	A	C	MI.23941	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	120	40	C	W	tgT/tgG	-0,27	0	0,01	probably_damaging	1	neutral	0,08	neutral	2,22	deleterious	-7,64	deleterious	-10,98	high_impact	3,99	damaging	0,48	damaging	0,07	deleterious	3,8	23,4	0,19	0,45	disease	0,96	disease	0,99	disease	0,84	disease	0,84	7	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,94	low_impact	-3,55	medium_impact	-0,38	high_impact	2,2	0,44	0,8	48,67	8,5	N	0,47	N	0,96	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14554	14554	A	T	MI.23942	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	120	40	C	W	tgT/tgA	-0,27	0	0,01	probably_damaging	1	neutral	0,08	neutral	2,22	deleterious	-7,64	deleterious	-10,98	high_impact	3,99	damaging	0,48	damaging	0,07	deleterious	3,83	23,4	0,19	0,45	disease	0,96	disease	0,99	disease	0,84	disease	0,84	7	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,94	low_impact	-3,55	medium_impact	-0,38	high_impact	2,2	0,44	0,8	48,67	8,5	N	0,47	N	0,96	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14555	14555	C	T	MI.23943	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	119	40	C	Y	tGt/tAt	1,56	0,73	0	probably_damaging	1	neutral	0,34	neutral	2,23	deleterious	-5,89	deleterious	-10,98	high_impact	3,99	damaging	0,51	damaging	0,07	deleterious	3,75	23,3	0,28	0,45	disease	0,91	disease	0,99	disease	0,8	disease	0,85	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,94	low_impact	-3,55	medium_impact	0,05	high_impact	2,2	0,69	0,85	48,67	8,5	N	0,51	P	0,94	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14555	14555	C	A	MI.23944	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	119	40	C	F	tGt/tTt	1,56	0,73	0	probably_damaging	1	neutral	0,34	neutral	2,24	deleterious	-5,52	deleterious	-10,98	high_impact	3,99	damaging	0,5	damaging	0,08	deleterious	4,21	23,9	0,24	0,45	disease	0,89	disease	0,99	disease	0,77	disease	0,88	8	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,94	low_impact	-3,55	medium_impact	0,05	high_impact	2,2	0,55	0,8	48,67	8,5	P	0,51	P	0,94	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14555	14555	C	G	MI.23945	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	119	40	C	S	tGt/tCt	1,56	0,73	0	probably_damaging	1	neutral	0,46	neutral	2,49	neutral	-2,47	deleterious	-9,98	medium_impact	3,1	neutral	0,68	neutral	0,41	deleterious	3,21	22,7	0,28	0,45	disease	0,74	disease	0,97	disease	0,72	disease	0,82	6	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,91	low_impact	-3,55	medium_impact	0,17	medium_impact	1,46	0,53	0,8	48,67	8,5	N	0,35	N	0,47	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14556	14556	A	G	MI.23946	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	118	40	C	R	Tgt/Cgt	3,4	0,99	0	probably_damaging	1	neutral	0,1	neutral	2,24	deleterious	-5,18	deleterious	-11,98	high_impact	3,99	damaging	0,47	damaging	0,07	deleterious	3,41	23	0,2	0,45	disease	0,88	disease	0,99	disease	0,85	disease	0,89	8	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,94	low_impact	-3,55	medium_impact	-0,32	high_impact	2,2	0,48	0,8	48,67	8,5	P	0,65	P	0,89	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14556	14556	A	T	MI.23947	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	118	40	C	S	Tgt/Agt	3,4	0,99	0	probably_damaging	1	neutral	0,46	neutral	2,49	neutral	-2,47	deleterious	-9,98	medium_impact	3,1	neutral	0,68	neutral	0,41	deleterious	2,94	22	0,28	0,45	disease	0,74	disease	0,97	disease	0,72	disease	0,82	6	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,91	low_impact	-3,55	medium_impact	0,17	medium_impact	1,46	0,53	0,8	48,67	8,5	N	0,5	N	0,47	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14556	14556	A	C	MI.23948	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	118	40	C	G	Tgt/Ggt	3,4	0,99	0	probably_damaging	1	neutral	0,42	neutral	2,31	deleterious	-3,94	deleterious	-11,98	medium_impact	3,19	neutral	0,62	damaging	0,14	deleterious	2,8	21,4	0,22	0,45	disease	0,76	disease	0,97	disease	0,76	disease	0,87	7	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,89	low_impact	-3,55	medium_impact	0,13	medium_impact	1,53	0,37	0,8	48,67	8,5	N	0,51	P	0,74	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14558	14558	C	T	MI.23949	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	116	39	G	E	gGg/gAg	-10,6	0	0	probably_damaging	1	neutral	0,27	neutral	2,23	deleterious	-4,98	deleterious	-7,99	high_impact	3,99	damaging	0,53	damaging	0,02	deleterious	3,94	23,5	0,34	0,5	disease	0,79	disease	0,97	disease	0,85	disease	0,91	8	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	-0,03	high_impact	2,2	0,8	0,85	18,58	19,57	N	0,39	N	1	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6142	6142	A	G	MI.2395	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	239	80	N	S	aAc/aGc	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,69	neutral	-2,98	deleterious	-3,4	high_impact	4,3	damaging	0,59	damaging	0,14	deleterious	3,02	22,3	0,62	0,65	disease	0,77	disease	0,84	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,64	low_impact	-1,48	high_impact	2,87	0,46	0,9	2,34	6,63	P	0,51	P	0,79	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14558	14558	C	G	MI.23950	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	116	39	G	A	gGg/gCg	-10,6	0	0	probably_damaging	1	neutral	0,51	neutral	2,31	neutral	-2,48	deleterious	-5,99	medium_impact	3,19	neutral	0,61	damaging	0,08	deleterious	3,19	22,7	0,47	0,55	neutral	0,44	disease	0,92	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,86	low_impact	-3,55	medium_impact	0,22	medium_impact	1,53	0,86	0,9	18,58	19,57	N	0,28	N	0,78	NA	NA	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14558	14558	C	A	MI.23951	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	116	39	G	V	gGg/gTg	-10,6	0	0	probably_damaging	1	neutral	0,51	neutral	2,46	deleterious	-4,25	deleterious	-8,98	high_impact	3,64	damaging	0,5	damaging	0,04	deleterious	4,13	23,8	0,27	0,45	disease	0,66	disease	0,98	disease	0,78	disease	0,9	8	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,91	low_impact	-3,55	medium_impact	0,22	medium_impact	1,91	0,77	0,85	18,58	19,57	N	0,4	N	0,98	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14559	14559	C	A	MI.23952	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	115	39	G	W	Ggg/Tgg	5	0,96	0	probably_damaging	1	neutral	0,19	neutral	2,23	deleterious	-8,05	deleterious	-7,99	high_impact	3,99	damaging	0,54	damaging	0,01	deleterious	4,73	24,6	0,22	0,45	disease	0,95	disease	0,97	disease	0,81	disease	0,9	8	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,93	low_impact	-3,55	medium_impact	-0,14	high_impact	2,2	0,59	0,8	18,58	19,57	P	0,57	P	1	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14559	14559	C	G	MI.23953	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	115	39	G	R	Ggg/Cgg	5	0,96	0	probably_damaging	1	neutral	0,35	neutral	2,24	deleterious	-5,23	deleterious	-7,99	high_impact	3,99	damaging	0,52	damaging	0,02	deleterious	4,05	23,7	0,19	0,45	disease	0,79	disease	0,97	disease	0,85	disease	0,93	9	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	0,06	high_impact	2,2	0,79	0,85	18,58	19,57	P	0,56	P	1	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14561	14561	A	G	MI.23954	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	113	38	V	A	gTc/gCc	-5,55	0	0	possibly_damaging	0,69	neutral	0,57	neutral	2,26	neutral	-0,67	deleterious	-2,94	low_impact	1,25	neutral	0,85	neutral	0,96	deleterious	2,48	19,33	0,44	0,55	neutral	0,25	neutral	0,39	neutral	0,5	neutral	0,45	1	neutral	0,64	neutral	0,44	neutral	-3	deleterious	0,6	low_impact	-1,11	medium_impact	0,27	medium_impact	-0,09	0,7	0,85	15,49	18,25	N	0,28	N	0,72	NA	NA	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14561	14561	A	C	MI.23955	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	113	38	V	G	gTc/gGc	-5,55	0	0	probably_damaging	0,96	neutral	0,45	neutral	2,32	neutral	-0,04	deleterious	-5,86	medium_impact	2,04	neutral	0,71	neutral	0,65	deleterious	3,86	23,5	0,28	0,45	disease	0,64	disease	0,68	disease	0,63	disease	0,55	1	neutral	0,96	neutral	0,25	deleterious	1	deleterious	0,75	low_impact	-2,06	medium_impact	0,16	medium_impact	0,57	0,64	0,8	15,49	18,25	N	0,29	N	0,9	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14561	14561	A	T	MI.23956	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	113	38	V	D	gTc/gAc	-5,55	0	0	probably_damaging	0,97	neutral	0,2	neutral	2,17	deleterious	-4,46	deleterious	-5,84	medium_impact	3,43	neutral	0,62	neutral	0,38	deleterious	4,53	24,3	0,15	0,4	disease	0,74	disease	0,83	disease	0,8	disease	0,83	7	deleterious	0,98	neutral	0,12	deleterious	1	deleterious	0,82	low_impact	-2,18	medium_impact	-0,13	medium_impact	1,73	0,75	0,85	15,49	18,25	N	0,38	N	0,9	NA	NA	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14562	14562	C	G	MI.23957	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	112	38	V	L	Gtc/Ctc	1,1	0	0	possibly_damaging	0,45	neutral	0,84	neutral	2,35	neutral	0,28	neutral	-1,77	low_impact	1,67	neutral	0,88	neutral	0,85	deleterious	0,64	8,45	0,42	0,55	neutral	0,18	neutral	0,45	neutral	0,44	neutral	0,45	1	neutral	0,34	deleterious	0,7	neutral	-3	neutral	0,41	medium_impact	-0,72	medium_impact	0,61	medium_impact	0,26	0,8	0,85	15,49	18,25	N	0,31	N	0,38	NA	NA	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14562	14562	C	A	MI.23958	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	112	38	V	F	Gtc/Ttc	1,1	0	0	probably_damaging	0,92	neutral	0,79	neutral	2,27	neutral	-0,6	deleterious	-3,72	low_impact	1,76	neutral	0,85	neutral	0,73	deleterious	2,94	22	0,26	0,45	neutral	0,47	disease	0,74	neutral	0,47	disease	0,59	2	neutral	0,91	neutral	0,44	neutral	-2	deleterious	0,74	low_impact	-1,77	medium_impact	0,53	medium_impact	0,33	0,83	0,85	15,49	18,25	N	0,22	N	0,82	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14562	14562	C	T	MI.23959	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	112	38	V	I	Gtc/Atc	1,1	0	0	benign	0,06	neutral	0,5	neutral	2,28	neutral	-0,41	neutral	-0,52	medium_impact	2,04	neutral	0,91	neutral	0,86	deleterious	0,51	7,49	0,51	0,6	neutral	0,16	neutral	0,37	neutral	0,5	neutral	0,45	1	neutral	0,44	deleterious	0,72	neutral	-3	neutral	0,15	medium_impact	0,3	medium_impact	0,21	medium_impact	0,57	0,74	0,85	15,49	18,25	N	0,37	N	0,06	NA	NA	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6143	6143	C	A	MI.2396	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	240	80	N	K	aaC/aaA	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-3,49	deleterious	-4,08	high_impact	5,2	damaging	0,43	damaging	0,14	deleterious	4,25	23,9	0,54	0,6	disease	0,8	disease	0,92	disease	0,77	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,7	0,67	0,9	2,34	6,63	P	0,81	P	0,92	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14564	14564	A	T	MI.23960	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	110	37	V	E	gTg/gAg	-11,05	0	0	possibly_damaging	0,46	neutral	0,27	neutral	2,13	deleterious	-4,03	neutral	-0,03	medium_impact	2,77	neutral	0,65	neutral	0,54	deleterious	3,79	23,4	0,22	0,45	neutral	0,42	disease	0,92	disease	0,78	disease	0,83	6	neutral	0,7	neutral	0,41	NA	0	deleterious	0,64	medium_impact	-0,73	medium_impact	-0,03	medium_impact	1,18	0,73	0,85	20,35	20,89	N	0,46	N	0,57	NA	NA	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14564	14564	A	G	MI.23961	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	110	37	V	A	gTg/gCg	-11,05	0	0	benign	0	neutral	0,51	neutral	2,17	neutral	-1,87	neutral	2,75	neutral_impact	0,12	neutral	0,91	neutral	0,98	deleterious	-0,02	2,41	0,44	0,55	neutral	0,21	disease	0,51	neutral	0,44	neutral	0,45	1	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,17	medium_impact	1,95	medium_impact	0,22	low_impact	-1,04	0,67	0,85	20,35	20,89	N	0,37	N	0,01	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14564	14564	A	C	MI.23962	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	110	37	V	G	gTg/gGg	-11,05	0	0	benign	0,01	neutral	0,33	neutral	2,2	neutral	-1,36	neutral	5,51	neutral_impact	-0,3	neutral	0,83	neutral	0,96	neutral	-1,16	0,01	0,29	0,45	neutral	0,12	neutral	0,25	neutral	0,41	neutral	0,42	2	neutral	0,66	deleterious	0,66	neutral	-6	neutral	0,12	medium_impact	1,03	medium_impact	0,04	low_impact	-1,39	0,65	0,8	20,35	20,89	N	0,35	N	0,25	NA	NA	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14565	14565	C	G	MI.23963	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	109	37	V	L	Gtg/Ctg	-0,73	0	0	benign	0,11	neutral	0,65	neutral	2,51	neutral	1,01	neutral	-0,95	low_impact	1,45	neutral	0,73	neutral	0,73	neutral	1,67	14,24	0,4	0,5	neutral	0,13	disease	0,66	neutral	0,4	neutral	0,47	1	neutral	0,24	deleterious	0,77	neutral	-6	neutral	0,2	medium_impact	0,04	medium_impact	0,36	medium_impact	0,08	0,77	0,85	20,35	20,89	N	0,32	N	0,53	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14565	14565	C	A	MI.23964	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	109	37	V	L	Gtg/Ttg	-0,73	0	0	benign	0,11	neutral	0,65	neutral	2,51	neutral	1,01	neutral	-0,95	low_impact	1,45	neutral	0,73	neutral	0,73	deleterious	2	16,24	0,4	0,5	neutral	0,13	disease	0,66	neutral	0,4	neutral	0,47	1	neutral	0,24	deleterious	0,77	neutral	-6	neutral	0,2	medium_impact	0,04	medium_impact	0,36	medium_impact	0,08	0,77	0,85	20,35	20,89	N	0,37	N	0,53	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14565	14565	C	T	MI.23965	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	109	37	V	M	Gtg/Atg	-0,73	0	0	possibly_damaging	0,72	neutral	0,22	neutral	2,18	neutral	-1,74	neutral	-0,29	medium_impact	2,42	neutral	0,64	neutral	0,69	deleterious	1,94	15,84	0,41	0,5	neutral	0,32	disease	0,62	disease	0,59	disease	0,73	5	neutral	0,83	neutral	0,25	NA	0	deleterious	0,56	low_impact	-1,17	medium_impact	-0,1	medium_impact	0,89	0,81	0,85	20,35	20,89	N	0,45	N	0,54	NA	NA	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14567	14567	C	T	MI.23966	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	107	36	G	D	gGt/gAt	-5,78	0	0	probably_damaging	1	neutral	0,2	neutral	2,28	neutral	-2,58	deleterious	-6,98	high_impact	3,6	neutral	0,62	neutral	0,32	deleterious	3,95	23,6	0,14	0,4	disease	0,62	disease	0,91	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,13	medium_impact	1,88	0,57	0,8	29,2	23,72	N	0,38	N	0,96	NA	NA	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14567	14567	C	G	MI.23967	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	107	36	G	A	gGt/gCt	-5,78	0	0	probably_damaging	1	neutral	0,81	neutral	2,43	neutral	1,84	deleterious	-5,99	low_impact	1,25	damaging	0,55	neutral	0,41	deleterious	3,23	22,8	0,42	0,55	neutral	0,12	neutral	0,34	neutral	0,35	neutral	0,44	1	deleterious	1	neutral	0,41	neutral	-2	deleterious	0,7	low_impact	-3,55	medium_impact	0,56	medium_impact	-0,09	0,8	0,85	29,2	23,72	N	0,3	N	0,78	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14567	14567	C	A	MI.23968	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	107	36	G	V	gGt/gTt	-5,78	0	0	probably_damaging	1	neutral	0,64	neutral	2,41	neutral	1,59	deleterious	-8,98	medium_impact	3,04	neutral	0,62	neutral	0,41	deleterious	4,07	23,7	0,23	0,45	disease	0,53	disease	0,91	disease	0,69	disease	0,78	6	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,86	low_impact	-3,55	medium_impact	0,35	medium_impact	1,41	0,72	0,85	29,2	23,72	N	0,35	N	0,98	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14568	14568	C	G	MI.23969	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	106	36	G	R	Ggt/Cgt	3,17	0,97	0	probably_damaging	1	neutral	0,33	neutral	2,29	neutral	-1,39	deleterious	-7,98	high_impact	3,6	neutral	0,61	damaging	0,26	deleterious	3,99	23,6	0,13	0,4	disease	0,65	disease	0,93	disease	0,78	disease	0,85	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	0,04	medium_impact	1,88	0,76	0,85	29,2	23,72	P	0,57	P	1	NA	NA	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6143	6143	C	G	MI.2397	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	240	80	N	K	aaC/aaG	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-3,49	deleterious	-4,08	high_impact	5,2	damaging	0,43	damaging	0,14	deleterious	3,87	23,5	0,54	0,6	disease	0,8	disease	0,92	disease	0,77	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,7	0,67	0,9	2,34	6,63	P	0,81	P	0,92	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14568	14568	C	A	MI.23970	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	106	36	G	C	Ggt/Tgt	3,17	0,97	0	probably_damaging	1	neutral	0,23	neutral	2,31	neutral	-0,48	deleterious	-8,98	medium_impact	3,25	neutral	0,67	damaging	0,27	deleterious	4,54	24,3	0,21	0,45	disease	0,69	disease	0,92	disease	0,67	disease	0,81	6	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,88	low_impact	-3,55	medium_impact	-0,09	medium_impact	1,58	0,79	0,85	29,2	23,72	P	0,53	P	0,97	NA	NA	0,57	.	.	.	.	.	.	COSM1138272	.	.	.	.	.	.	.	.
chrM	14568	14568	C	T	MI.23971	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	106	36	G	S	Ggt/Agt	3,17	0,97	0	probably_damaging	1	neutral	0,64	neutral	2,47	neutral	2,17	deleterious	-5,99	low_impact	1,72	damaging	0,27	damaging	0,23	deleterious	4,27	24	0,42	0,55	neutral	0,23	disease	0,52	neutral	0,37	neutral	0,46	1	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,73	low_impact	-3,55	medium_impact	0,35	medium_impact	0,3	0,77	0,85	29,2	23,72	P	0,9	P	1	NA	NA	0,53	rs397515506	Pathogenic	Leber's_optic_atrophy	RCV000055703.1	MedGen:OMIM:SNOMED_CT	.	.	.	.	C14568T	LHON	+	-	Cfrm	9
chrM	14570	14570	C	A	MI.23972	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	104	35	S	I	aGc/aTc	-2,57	0	0	probably_damaging	1	neutral	0,48	neutral	2,28	deleterious	-3,6	deleterious	-5,61	high_impact	3,62	neutral	0,65	neutral	0,45	deleterious	4,34	24	0,32	0,5	neutral	0,44	disease	0,81	disease	0,65	disease	0,78	6	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,79	low_impact	-3,55	medium_impact	0,19	medium_impact	1,89	0,84	0,9	20,35	18,29	N	0,37	N	0,98	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14570	14570	C	T	MI.23973	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	104	35	S	N	aGc/aAc	-2,57	0	0	probably_damaging	1	neutral	0,15	neutral	2,22	deleterious	-3,69	deleterious	-2,87	high_impact	3,62	neutral	0,76	neutral	0,5	deleterious	3,63	23,2	0,55	0,6	disease	0,52	disease	0,61	disease	0,64	disease	0,73	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,79	low_impact	-3,55	medium_impact	-0,21	medium_impact	1,89	0,65	0,8	20,35	18,29	N	0,39	N	0,86	NA	NA	0,7	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14570	14570	C	G	MI.23974	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	104	35	S	T	aGc/aCc	-2,57	0	0	probably_damaging	1	neutral	0,28	neutral	2,28	neutral	-2,18	deleterious	-2,81	medium_impact	2,92	neutral	0,66	neutral	0,52	deleterious	3,5	23,1	0,31	0,5	neutral	0,35	neutral	0,49	neutral	0,42	disease	0,53	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	-0,02	medium_impact	1,31	0,71	0,85	20,35	18,29	N	0,44	N	0,69	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14571	14571	T	A	MI.23975	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	103	35	S	C	Agc/Tgc	0,18	0	0	probably_damaging	1	neutral	0,16	neutral	2,22	deleterious	-5,33	deleterious	-4,6	medium_impact	2,81	neutral	0,86	neutral	0,53	deleterious	3,47	23	0,29	0,45	disease	0,57	disease	0,78	neutral	0,45	disease	0,67	3	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,79	low_impact	-3,55	medium_impact	-0,19	medium_impact	1,21	0,78	0,85	20,35	18,29	N	0,38	N	0,99	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14571	14571	T	C	MI.23976	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	103	35	S	G	Agc/Ggc	0,18	0	0	probably_damaging	1	neutral	0,23	neutral	2,23	deleterious	-3,79	deleterious	-3,37	low_impact	1,64	neutral	0,87	neutral	0,95	deleterious	1,98	16,1	0,36	0,5	neutral	0,43	neutral	0,37	neutral	0,34	neutral	0,45	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,71	low_impact	-3,55	medium_impact	-0,09	medium_impact	0,23	0,65	0,8	20,35	18,29	N	0,48	N	0,82	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14571	14571	T	G	MI.23977	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	103	35	S	R	Agc/Cgc	0,18	0	0	probably_damaging	1	neutral	0,08	neutral	2,21	deleterious	-3,66	deleterious	-4,65	high_impact	3,62	neutral	0,66	neutral	0,31	deleterious	3,93	23,5	0,19	0,45	disease	0,55	disease	0,84	disease	0,73	disease	0,81	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,84	low_impact	-3,55	medium_impact	-0,38	medium_impact	1,89	0,82	0,85	20,35	18,29	N	0,36	N	1	NA	NA	0,71	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14573	14573	A	G	MI.23978	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	101	34	V	A	gTt/gCt	-9,91	0	0	benign	0,24	neutral	0,44	neutral	2,2	deleterious	-3,89	deleterious	-3,48	medium_impact	2,12	neutral	0,88	neutral	0,88	neutral	1,56	13,61	0,32	0,5	disease	0,53	disease	0,64	disease	0,51	disease	0,52	0	neutral	0,47	deleterious	0,6	neutral	-3	neutral	0,36	medium_impact	-0,34	medium_impact	0,15	medium_impact	0,64	0,68	0,85	9,73	14,65	N	0,36	N	0,46	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14573	14573	A	T	MI.23979	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	101	34	V	D	gTt/gAt	-9,91	0	0	possibly_damaging	0,84	deleterious	0,04	neutral	2,12	deleterious	-6,61	deleterious	-6,3	medium_impact	3,33	neutral	0,68	neutral	0,36	deleterious	3,8	23,4	0,13	0,4	disease	0,87	disease	0,89	disease	0,73	disease	0,83	7	neutral	0,98	neutral	0,1	deleterious	4	deleterious	0,77	low_impact	-1,46	medium_impact	-0,56	medium_impact	1,65	0,75	0,85	9,73	14,65	N	0,31	N	0,94	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6144	6144	T	G	MI.2398	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	241	81	W	G	Tga/Gga	0,13	0,97	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,66	deleterious	-8,7	high_impact	4,96	neutral	0,64	damaging	0,06	deleterious	3,83	23,4	0,25	0,55	disease	0,55	disease	0,87	disease	0,73	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,26	0,9	2,92	6,8	P	0,63	P	0,89	disease_causing	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14573	14573	A	C	MI.23980	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	101	34	V	G	gTt/gGt	-9,91	0	0	possibly_damaging	0,7	neutral	0,24	neutral	2,23	deleterious	-5,76	deleterious	-6,36	medium_impact	2,52	neutral	0,69	neutral	0,65	neutral	1,77	14,82	0,24	0,45	disease	0,81	disease	0,79	disease	0,59	disease	0,69	4	neutral	0,81	neutral	0,27	NA	0	deleterious	0,7	low_impact	-1,13	medium_impact	-0,07	medium_impact	0,97	0,68	0,85	9,73	14,65	N	0,32	N	0,92	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14574	14574	C	T	MI.23981	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	100	34	V	I	Gtt/Att	1,33	0	0	benign	0,02	neutral	0,75	neutral	2,39	neutral	-2,38	neutral	-0,56	low_impact	0,97	neutral	0,89	neutral	0,99	deleterious	0,01	2,7	0,39	0,5	neutral	0,21	neutral	0,39	neutral	0,34	neutral	0,44	1	neutral	0,22	deleterious	0,87	neutral	-6	neutral	0,15	medium_impact	0,75	medium_impact	0,47	medium_impact	-0,33	0,8	0,85	9,73	14,65	N	0,38	N	0,04	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14574	14574	C	G	MI.23982	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	100	34	V	L	Gtt/Ctt	1,33	0	0	benign	0,09	neutral	0,81	neutral	2,36	neutral	-1,76	neutral	-2,1	low_impact	1,32	neutral	0,85	neutral	0,8	deleterious	0,55	7,78	0,39	0,5	neutral	0,17	neutral	0,41	neutral	0,27	neutral	0,46	1	neutral	0,09	deleterious	0,86	neutral	-6	neutral	0,17	medium_impact	0,13	medium_impact	0,56	medium_impact	-0,03	0,8	0,85	9,73	14,65	N	0,3	N	0,66	NA	NA	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14574	14574	C	A	MI.23983	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	100	34	V	F	Gtt/Ttt	1,33	0	0	benign	0,02	neutral	0,28	neutral	2,26	neutral	-2	deleterious	-3,83	low_impact	1,14	neutral	0,93	neutral	0,64	deleterious	2,76	21,2	0,23	0,45	disease	0,59	disease	0,85	neutral	0,38	disease	0,61	2	neutral	0,71	deleterious	0,63	neutral	-6	neutral	0,28	medium_impact	0,75	medium_impact	-0,02	medium_impact	-0,19	0,74	0,85	9,73	14,65	N	0,47	N	0,85	NA	NA	0,53	rs386829218	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14575	14575	A	C	MI.23984	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	99	33	I	M	atT/atG	-2,11	0	0	possibly_damaging	0,69	neutral	0,28	neutral	1,94	deleterious	-4,33	deleterious	-2,64	medium_impact	2,28	neutral	0,71	neutral	0,62	deleterious	2,64	20,4	0,33	0,5	disease	0,58	disease	0,74	disease	0,55	disease	0,67	3	neutral	0,78	neutral	0,3	NA	0	deleterious	0,63	low_impact	-1,11	medium_impact	-0,02	medium_impact	0,77	0,8	0,85	19,47	19,69	N	0,36	N	0,87	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14575	14575	A	T	MI.23985	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	99	33	I	M	atT/atA	-2,11	0	0	possibly_damaging	0,69	neutral	0,28	neutral	1,94	deleterious	-4,33	deleterious	-2,64	medium_impact	2,28	neutral	0,71	neutral	0,62	deleterious	2,69	20,8	0,33	0,5	disease	0,58	disease	0,74	disease	0,55	disease	0,67	3	neutral	0,78	neutral	0,3	NA	0	deleterious	0,63	low_impact	-1,11	medium_impact	-0,02	medium_impact	0,77	0,8	0,85	19,47	19,69	N	0,32	N	0,87	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14576	14576	A	C	MI.23986	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	98	33	I	S	aTt/aGt	-1,19	0	0	benign	0,3	neutral	0,21	neutral	1,89	deleterious	-6,19	deleterious	-5,65	medium_impact	3,18	damaging	0,45	neutral	0,34	deleterious	2,11	16,91	0,24	0,45	disease	0,73	disease	0,92	disease	0,64	disease	0,8	6	neutral	0,75	neutral	0,46	neutral	-3	deleterious	0,48	medium_impact	-0,46	medium_impact	-0,11	medium_impact	1,52	0,55	0,8	19,47	19,69	N	0,36	N	0,97	NA	NA	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14576	14576	A	T	MI.23987	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	98	33	I	N	aTt/aAt	-1,19	0	0	possibly_damaging	0,69	neutral	0,05	neutral	1,87	deleterious	-7,23	deleterious	-6,65	medium_impact	3,18	damaging	0,47	neutral	0,37	deleterious	3,78	23,4	0,28	0,45	disease	0,84	disease	0,92	disease	0,67	disease	0,81	6	neutral	0,96	neutral	0,18	NA	0	deleterious	0,68	low_impact	-1,11	medium_impact	-0,5	medium_impact	1,52	0,58	0,8	19,47	19,69	N	0,39	N	0,99	NA	NA	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14576	14576	A	G	MI.23988	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	98	33	I	T	aTt/aCt	-1,19	0	0	benign	0,02	neutral	0,29	neutral	1,9	deleterious	-5,25	deleterious	-4,42	medium_impact	3,18	damaging	0,47	neutral	0,36	neutral	1,53	13,45	0,41	0,5	disease	0,57	disease	0,79	disease	0,64	disease	0,76	5	neutral	0,7	deleterious	0,64	neutral	-3	neutral	0,29	medium_impact	0,75	medium_impact	-0,01	medium_impact	1,52	0,63	0,8	19,47	19,69	N	0,48	N	0,92	NA	NA	0,67	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14577	14577	T	A	MI.23989	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	97	33	I	F	Att/Ttt	3,85	0,1	0,01	possibly_damaging	0,5	neutral	0,23	neutral	1,91	deleterious	-4,68	deleterious	-3,91	medium_impact	3,18	damaging	0,5	neutral	0,37	deleterious	3,76	23,3	0,34	0,5	disease	0,63	disease	0,91	disease	0,68	disease	0,81	6	neutral	0,75	neutral	0,37	NA	0	deleterious	0,66	medium_impact	-0,8	medium_impact	-0,09	medium_impact	1,52	0,79	0,85	19,47	19,69	N	0,49	N	0,93	NA	NA	0,66	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6144	6144	T	C	MI.2399	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	241	81	W	R	Tga/Cga	0,13	0,97	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,6	deleterious	-9,36	high_impact	4,96	damaging	0,6	damaging	0,05	deleterious	3,51	23,1	0,24	0,55	disease	0,53	disease	0,95	disease	0,78	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,29	0,9	2,92	6,8	P	0,61	P	0,98	disease_causing	0,98	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14577	14577	T	G	MI.23990	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	97	33	I	L	Att/Ctt	3,85	0,1	0,01	benign	0,01	neutral	0,83	neutral	2,08	neutral	-0,82	neutral	-1,85	medium_impact	2,13	neutral	0,67	neutral	0,54	deleterious	2,01	16,26	0,27	0,45	neutral	0,3	disease	0,77	disease	0,54	disease	0,73	5	neutral	0,14	deleterious	0,91	neutral	-3	neutral	0,21	medium_impact	1,03	medium_impact	0,59	medium_impact	0,64	0,64	0,8	19,47	19,69	N	0,4	N	0,62	NA	NA	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14577	14577	T	C	MI.23991	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	97	33	I	V	Att/Gtt	3,85	0,1	0,01	benign	0,01	neutral	1	neutral	2,14	neutral	-2,51	neutral	-0,51	neutral_impact	-0,12	neutral	0,98	neutral	0,93	neutral	-0,75	0,06	0,33	0,5	neutral	0,1	neutral	0,21	neutral	0,37	neutral	0,32	4	neutral	0,01	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,03	high_impact	1,87	low_impact	-1,24	0,59	0,8	19,47	19,69	N	0,5	N	0,15	NA	NA	0,21	rs386829219	.	.	.	.	.	.	CPD	12,93	T14577C	MIDM	-	+	Reported	1
chrM	14578	14578	C	A	MI.23992	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	96	32	L	F	ttG/ttT	0,41	0,01	0	probably_damaging	1	neutral	0,25	neutral	1,51	deleterious	-5,39	deleterious	-3,98	high_impact	3,65	damaging	0,56	damaging	0,1	deleterious	3,97	23,6	0,33	0,5	disease	0,65	disease	0,89	disease	0,71	disease	0,79	6	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	-0,06	medium_impact	1,92	0,51	0,8	29,2	19,38	N	0,3	N	0,95	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14578	14578	C	G	MI.23993	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	96	32	L	F	ttG/ttC	0,41	0,01	0	probably_damaging	1	neutral	0,25	neutral	1,51	deleterious	-5,39	deleterious	-3,98	high_impact	3,65	damaging	0,56	damaging	0,1	deleterious	3,51	23,1	0,33	0,5	disease	0,65	disease	0,89	disease	0,71	disease	0,79	6	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	-0,06	medium_impact	1,92	0,51	0,8	29,2	19,38	N	0,32	N	0,95	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14579	14579	A	G	MI.23994	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	95	32	L	S	tTg/tCg	-5,09	0	0	probably_damaging	1	neutral	0,3	neutral	1,45	deleterious	-6,57	deleterious	-5,96	high_impact	4	damaging	0,4	damaging	0,04	deleterious	3,72	23,3	0,17	0,45	disease	0,83	disease	0,93	disease	0,75	disease	0,85	7	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0	high_impact	2,21	0,61	0,8	29,2	19,38	N	0,48	N	0,97	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14579	14579	A	C	MI.23995	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	95	32	L	W	tTg/tGg	-5,09	0	0	probably_damaging	1	neutral	0,07	neutral	1,42	deleterious	-8,33	deleterious	-5,97	high_impact	4	damaging	0,41	damaging	0,04	deleterious	3,28	22,8	0,13	0,4	disease	0,92	disease	0,89	disease	0,76	disease	0,86	7	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,42	high_impact	2,21	0,57	0,8	29,2	19,38	N	0,45	N	0,98	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14580	14580	A	T	MI.23996	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	94	32	L	M	Ttg/Atg	5,46	0,55	0	probably_damaging	1	neutral	0,1	neutral	1,47	deleterious	-5,28	neutral	-1,99	high_impact	4	damaging	0,5	damaging	0,07	deleterious	3,23	22,8	0,26	0,45	disease	0,62	disease	0,8	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,81	low_impact	-3,55	medium_impact	-0,32	high_impact	2,21	0,58	0,8	29,2	19,38	N	0,51	P	0,87	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14582	14582	A	G	MI.23997	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	92	31	V	A	gTa/gCa	-12,89	0	0,03	benign	0,02	neutral	0,54	neutral	2,33	neutral	-0,49	neutral	1,87	neutral_impact	0,18	neutral	0,96	neutral	0,89	neutral	-0,52	0,2	0,43	0,55	neutral	0,2	neutral	0,49	neutral	0,36	neutral	0,44	1	neutral	0,44	deleterious	0,76	neutral	-6	neutral	0,17	medium_impact	0,75	medium_impact	0,25	medium_impact	-0,99	0,78	0,85	28,32	22,32	N	0,26	N	0,11	NA	NA	0,19	rs41354845	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14582	14582	A	C	MI.23998	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	92	31	V	G	gTa/gGa	-12,89	0	0,03	benign	0,03	neutral	0,5	neutral	2,3	deleterious	-3,99	neutral	4,59	neutral_impact	-0,95	neutral	0,84	neutral	0,96	neutral	-1,2	0,01	0,3	0,45	neutral	0,11	neutral	0,18	neutral	0,33	neutral	0,24	5	neutral	0,47	deleterious	0,74	neutral	-6	neutral	0,11	medium_impact	0,59	medium_impact	0,21	low_impact	-1,94	0,7	0,85	28,32	22,32	N	0,31	N	0,3	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14582	14582	A	T	MI.23999	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	92	31	V	E	gTa/gAa	-12,89	0	0,03	possibly_damaging	0,7	neutral	0,27	neutral	2,22	deleterious	-4,02	neutral	-0,24	medium_impact	2,25	damaging	0,56	neutral	0,42	deleterious	3,51	23,1	0,21	0,45	neutral	0,3	disease	0,86	disease	0,66	disease	0,82	6	neutral	0,79	neutral	0,29	NA	0	deleterious	0,63	low_impact	-1,13	medium_impact	-0,03	medium_impact	0,75	0,81	0,85	28,32	22,32	N	0,35	N	0,63	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8536	8536	A	T	MI.24	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	10	4	N	Y	Aat/Tat	6,84	1	0	possibly_damaging	0,63	deleterious	0	neutral	4,41	neutral	-2,72	deleterious	-5,64	medium_impact	2,85	neutral	0,91	neutral	0,36	deleterious	3,87	23,5	0,47	0,65	disease	0,86	disease	0,53	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,19	deleterious	4	deleterious	0,62	medium_impact	-0,98	low_impact	-1,4	medium_impact	1,35	0,48	0,9	41,59	7,51	P	0,68	P	0,97	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8639	8639	T	C	MI.240	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	113	38	I	T	aTc/aCc	-3,8	0	0	probably_damaging	0,99	neutral	0,14	neutral	4,29	neutral	-1,18	deleterious	-2,86	low_impact	1,82	neutral	0,96	neutral	0,96	deleterious	2,18	17,39	0,55	0,65	neutral	0,36	neutral	0,47	neutral	0,4	neutral	0,47	1	deleterious	0,99	neutral	0,08	neutral	-2	deleterious	0,68	low_impact	-2,65	medium_impact	-0,15	medium_impact	0,46	0,38	0,9	15,49	18,25	N	0,45	N	0,91	polymorphism	1	0,05	rs200047468	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6145	6145	G	T	MI.2400	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	242	81	W	L	tGa/tTa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,84	neutral	0,35	deleterious	-8,65	high_impact	3,6	neutral	0,67	damaging	0,04	deleterious	4,12	23,8	0,21	0,55	neutral	0,21	disease	0,9	disease	0,7	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,23	0,21	0,9	2,92	6,8	N	0,49	N	0,95	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14583	14583	C	A	MI.24000	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	91	31	V	L	Gta/Tta	0,41	0	0	benign	0,37	neutral	0,81	neutral	2,54	neutral	-1,57	neutral	-0,99	low_impact	1,9	damaging	0,56	neutral	0,48	deleterious	2,12	16,96	0,41	0,5	neutral	0,31	disease	0,51	neutral	0,49	disease	0,54	1	neutral	0,26	deleterious	0,72	neutral	-6	neutral	0,38	medium_impact	-0,58	medium_impact	0,56	medium_impact	0,45	0,78	0,85	28,32	22,32	N	0,35	N	0,59	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14583	14583	C	G	MI.24001	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	91	31	V	L	Gta/Cta	0,41	0	0	benign	0,37	neutral	0,81	neutral	2,54	neutral	-1,57	neutral	-0,99	low_impact	1,9	damaging	0,56	neutral	0,48	deleterious	1,89	15,53	0,41	0,5	neutral	0,31	disease	0,51	neutral	0,49	disease	0,54	1	neutral	0,26	deleterious	0,72	neutral	-6	neutral	0,38	medium_impact	-0,58	medium_impact	0,56	medium_impact	0,45	0,78	0,85	28,32	22,32	N	0,32	N	0,59	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14583	14583	C	T	MI.24002	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	91	31	V	M	Gta/Ata	0,41	0	0	probably_damaging	0,94	neutral	0,26	neutral	2,27	deleterious	-3,2	neutral	-0,24	medium_impact	2,25	neutral	0,74	neutral	0,53	deleterious	3,68	23,3	0,44	0,55	neutral	0,5	disease	0,52	disease	0,53	disease	0,61	2	neutral	0,95	neutral	0,16	deleterious	1	deleterious	0,72	low_impact	-1,89	medium_impact	-0,05	medium_impact	0,75	0,81	0,85	28,32	22,32	N	0,44	N	0,6	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14584	14584	T	A	MI.24003	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	90	30	L	F	ttA/ttT	-0,27	0	0	probably_damaging	0,98	neutral	0,41	neutral	1,98	neutral	-1,92	neutral	-2,14	low_impact	1,9	neutral	0,83	neutral	0,83	deleterious	2,63	20,4	0,43	0,55	neutral	0,2	disease	0,53	neutral	0,43	neutral	0,46	1	neutral	0,98	neutral	0,22	neutral	-2	deleterious	0,69	low_impact	-2,35	medium_impact	0,12	medium_impact	0,45	0,68	0,85	17,7	14,1	N	0,31	N	0,95	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14584	14584	T	G	MI.24004	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	90	30	L	F	ttA/ttC	-0,27	0	0	probably_damaging	0,98	neutral	0,41	neutral	1,98	neutral	-1,92	neutral	-2,14	low_impact	1,9	neutral	0,83	neutral	0,83	deleterious	2,39	18,73	0,43	0,55	neutral	0,2	disease	0,53	neutral	0,43	neutral	0,46	1	neutral	0,98	neutral	0,22	neutral	-2	deleterious	0,69	low_impact	-2,35	medium_impact	0,12	medium_impact	0,45	0,68	0,85	17,7	14,1	N	0,32	N	0,95	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14585	14585	A	C	MI.24005	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	89	30	L	W	tTa/tGa	-11,28	0	0	probably_damaging	1	deleterious	0,04	neutral	1,89	deleterious	-6,94	deleterious	-3,99	medium_impact	3,39	damaging	0,39	damaging	0,08	deleterious	3,23	22,8	0,15	0,4	disease	0,85	disease	0,82	disease	0,64	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,84	low_impact	-3,55	medium_impact	-0,56	medium_impact	1,7	0,68	0,85	17,7	14,1	N	0,38	N	0,98	NA	NA	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14585	14585	A	G	MI.24006	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	89	30	L	S	tTa/tCa	-11,28	0	0	probably_damaging	0,98	neutral	0,15	neutral	1,94	deleterious	-5,23	deleterious	-4,45	high_impact	3,73	damaging	0,39	damaging	0,1	deleterious	3,68	23,3	0,22	0,45	disease	0,72	disease	0,86	disease	0,7	disease	0,77	5	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-2,35	medium_impact	-0,21	medium_impact	1,99	0,64	0,8	17,7	14,1	N	0,38	N	0,97	NA	NA	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14586	14586	A	C	MI.24007	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	88	30	L	V	Tta/Gta	3,63	0,09	0	benign	0,36	neutral	0,32	neutral	2,19	deleterious	-3,92	neutral	-0,97	low_impact	1,56	neutral	0,8	neutral	0,78	neutral	1,42	12,9	0,35	0,5	neutral	0,27	disease	0,51	neutral	0,41	neutral	0,47	1	neutral	0,62	deleterious	0,48	neutral	-6	deleterious	0,48	medium_impact	-0,57	medium_impact	0,03	medium_impact	0,17	0,77	0,85	17,7	14,1	N	0,44	N	0,71	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14586	14586	A	T	MI.24008	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	88	30	L	M	Tta/Ata	3,63	0,09	0	probably_damaging	0,98	neutral	0,12	neutral	1,96	deleterious	-4,61	neutral	-0,93	medium_impact	3,04	neutral	0,82	neutral	0,77	deleterious	2,79	21,3	0,36	0,5	neutral	0,45	disease	0,6	neutral	0,46	neutral	0,48	0	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,73	low_impact	-2,35	medium_impact	-0,27	medium_impact	1,41	0,76	0,85	17,7	14,1	N	0,42	N	0,87	NA	NA	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14588	14588	C	T	MI.24009	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	86	29	G	D	gGt/gAt	-6,24	0	0	probably_damaging	1	neutral	0,2	neutral	2,16	deleterious	-4,54	deleterious	-6,96	high_impact	3,58	neutral	0,68	damaging	0,04	deleterious	3,87	23,5	0,15	0,4	disease	0,61	disease	0,86	disease	0,72	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	-0,13	medium_impact	1,86	0,65	0,8	17,26	17,02	N	0,31	N	0,96	NA	NA	0,69	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6145	6145	G	C	MI.2401	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	242	81	W	S	tGa/tCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,74	neutral	-1,66	deleterious	-9,34	high_impact	4,96	neutral	0,62	damaging	0,05	deleterious	3,89	23,5	0,23	0,55	neutral	0,4	disease	0,93	disease	0,71	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,2	0,9	2,92	6,8	P	0,59	P	0,89	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14588	14588	C	A	MI.24010	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	86	29	G	V	gGt/gTt	-6,24	0	0	probably_damaging	1	neutral	0,69	neutral	2,39	neutral	0,54	deleterious	-8,95	low_impact	1,92	neutral	0,66	damaging	0,25	deleterious	4,2	23,9	0,25	0,45	neutral	0,18	disease	0,67	neutral	0,43	neutral	0,48	0	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,73	low_impact	-3,55	medium_impact	0,4	medium_impact	0,47	0,8	0,85	17,26	17,02	N	0,26	N	0,98	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14588	14588	C	G	MI.24011	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	86	29	G	A	gGt/gCt	-6,24	0	0	probably_damaging	1	neutral	0,79	neutral	2,32	neutral	0,01	deleterious	-5,96	low_impact	1,17	neutral	0,69	neutral	0,41	deleterious	3,23	22,8	0,4	0,5	neutral	0,15	neutral	0,2	neutral	0,3	neutral	0,36	3	deleterious	1	neutral	0,4	neutral	-2	deleterious	0,68	low_impact	-3,55	medium_impact	0,53	medium_impact	-0,16	0,89	0,9	17,26	17,02	N	0,23	N	0,78	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14589	14589	C	A	MI.24012	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	85	29	G	C	Ggt/Tgt	2,48	0,76	0	probably_damaging	1	neutral	0,18	neutral	2,18	neutral	-2,49	deleterious	-8,95	high_impact	3,58	neutral	0,71	damaging	0,03	deleterious	4,55	24,3	0,19	0,45	disease	0,67	disease	0,84	disease	0,63	disease	0,79	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,55	medium_impact	-0,16	medium_impact	1,86	0,84	0,9	17,26	17,02	N	0,36	N	0,97	NA	NA	0,69	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14589	14589	C	T	MI.24013	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	85	29	G	S	Ggt/Agt	2,48	0,76	0	probably_damaging	1	neutral	0,42	neutral	2,27	neutral	-0,52	deleterious	-5,96	medium_impact	2,77	neutral	0,69	damaging	0,08	deleterious	4,24	23,9	0,41	0,5	neutral	0,32	disease	0,7	disease	0,51	disease	0,58	2	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,76	low_impact	-3,55	medium_impact	0,13	medium_impact	1,18	0,85	0,9	17,26	17,02	N	0,28	N	1	NA	NA	0,56	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14589	14589	C	G	MI.24014	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	85	29	G	R	Ggt/Cgt	2,48	0,76	0	probably_damaging	1	neutral	0,33	neutral	2,16	deleterious	-3,4	deleterious	-7,95	high_impact	3,58	neutral	0,67	damaging	0,03	deleterious	4,05	23,7	0,13	0,4	disease	0,59	disease	0,84	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	0,04	medium_impact	1,86	0,77	0,85	17,26	17,02	N	0,43	N	1	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14591	14591	C	T	MI.24015	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	83	28	G	E	gGg/gAg	-14,5	0	0	probably_damaging	1	neutral	0,26	neutral	2,29	deleterious	-4,2	deleterious	-7,95	high_impact	3,75	neutral	0,64	damaging	0,07	deleterious	4,03	23,7	0,22	0,45	disease	0,66	disease	0,91	disease	0,79	disease	0,86	7	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	-0,05	high_impact	2	0,81	0,85	31,86	20,94	N	0,41	N	1	NA	NA	0,76	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14591	14591	C	A	MI.24016	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	83	28	G	V	gGg/gTg	-14,5	0	0	probably_damaging	1	neutral	0,52	neutral	2,37	deleterious	-4,01	deleterious	-8,95	medium_impact	3,4	neutral	0,61	damaging	0,06	deleterious	4,07	23,7	0,19	0,45	disease	0,62	disease	0,91	disease	0,72	disease	0,81	6	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,88	low_impact	-3,55	medium_impact	0,23	medium_impact	1,71	0,86	0,9	31,86	20,94	N	0,31	N	0,98	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14591	14591	C	G	MI.24017	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	83	28	G	A	gGg/gCg	-14,5	0	0	probably_damaging	1	neutral	0,63	neutral	2,42	neutral	-0,24	deleterious	-5,96	low_impact	1,17	neutral	0,63	neutral	0,42	deleterious	3,15	22,6	0,38	0,5	neutral	0,19	neutral	0,24	neutral	0,39	neutral	0,42	2	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,7	low_impact	-3,55	medium_impact	0,34	medium_impact	-0,16	0,86	0,9	31,86	20,94	N	0,34	N	0,78	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14592	14592	C	A	MI.24018	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	82	28	G	W	Ggg/Tgg	1,56	0,96	0	probably_damaging	1	neutral	0,18	neutral	2,27	deleterious	-7,77	deleterious	-7,96	high_impact	3,75	neutral	0,67	damaging	0,04	deleterious	4,76	24,7	0,17	0,45	disease	0,94	disease	0,91	disease	0,75	disease	0,87	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,55	medium_impact	-0,16	high_impact	2	0,69	0,85	31,86	20,94	N	0,48	N	1	NA	NA	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14592	14592	C	G	MI.24019	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	82	28	G	R	Ggg/Cgg	1,56	0,96	0	probably_damaging	1	neutral	0,33	neutral	2,44	deleterious	-4,69	deleterious	-7,95	high_impact	3,75	neutral	0,63	damaging	0,04	deleterious	4,01	23,6	0,15	0,45	disease	0,73	disease	0,91	disease	0,8	disease	0,85	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0,04	high_impact	2	0,81	0,85	31,86	20,94	N	0,51	P	1	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6146	6146	A	C	MI.2402	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	243	81	W	C	tgA/tgC	9,38	1	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,98	deleterious	-8,68	high_impact	4,96	damaging	0,56	damaging	0,04	deleterious	3,91	23,5	0,26	0,55	disease	0,62	disease	0,93	disease	0,75	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,31	0,9	2,92	6,8	P	0,63	P	0,88	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14594	14594	T	A	MI.24020	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	80	27	Y	F	tAt/tTt	1,33	1	0	probably_damaging	1	neutral	1	neutral	2,25	neutral	-1,17	deleterious	-3,98	low_impact	1,49	neutral	0,77	neutral	0,66	deleterious	2,41	18,89	0,47	0,55	neutral	0,26	neutral	0,21	neutral	0,41	neutral	0,33	3	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,71	low_impact	-3,55	high_impact	1,87	medium_impact	0,11	0,69	0,85	48,23	8,81	N	0,43	N	0,8	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14594	14594	T	C	MI.24021	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	80	27	Y	C	tAt/tGt	1,33	1	0	probably_damaging	1	neutral	0,08	neutral	2,17	deleterious	-6,27	deleterious	-8,95	medium_impact	3,44	neutral	0,69	damaging	0,05	deleterious	3,21	22,7	0,34	0,5	disease	0,91	disease	0,9	disease	0,73	disease	0,84	7	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,89	low_impact	-3,55	medium_impact	-0,38	medium_impact	1,74	0,43	0,8	48,23	8,81	N	0,47	N	1	NA	NA	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14594	14594	T	G	MI.24022	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	80	27	Y	S	tAt/tCt	1,33	1	0	probably_damaging	1	neutral	0,3	neutral	2,28	deleterious	-3,53	deleterious	-8,94	high_impact	3,78	neutral	0,67	damaging	0,06	deleterious	3,8	23,4	0,33	0,5	disease	0,79	disease	0,85	disease	0,68	disease	0,77	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	0	high_impact	2,03	0,44	0,8	48,23	8,81	N	0,49	N	0,96	NA	NA	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14595	14595	A	T	MI.24023	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	79	27	Y	N	Tat/Aat	1,56	1	0	probably_damaging	1	neutral	0,23	neutral	2,24	deleterious	-5,14	deleterious	-8,94	high_impact	3,78	neutral	0,65	damaging	0,09	deleterious	3,3	22,9	0,34	0,5	disease	0,81	disease	0,86	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,09	high_impact	2,03	0,46	0,8	48,23	8,81	N	0,49	N	1	NA	NA	0,81	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14595	14595	A	G	MI.24024	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	79	27	Y	H	Tat/Cat	1,56	1	0	probably_damaging	1	neutral	0,31	neutral	2,21	deleterious	-4,48	deleterious	-4,97	high_impact	3,78	neutral	0,65	damaging	0,05	deleterious	3,26	22,8	0,48	0,55	disease	0,67	disease	0,81	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	0,01	high_impact	2,03	0,68	0,85	48,23	8,81	N	0,53	P	0,98	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14595	14595	A	C	MI.24025	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	79	27	Y	D	Tat/Gat	1,56	1	0	probably_damaging	1	neutral	0,09	neutral	2,18	deleterious	-5,84	deleterious	-9,94	high_impact	3,78	neutral	0,7	damaging	0,05	deleterious	3,27	22,8	0,2	0,45	disease	0,89	disease	0,91	disease	0,77	disease	0,87	7	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	-0,35	high_impact	2,03	0,55	0,8	48,23	8,81	N	0,53	P	0,97	NA	NA	0,77	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14596	14596	A	T	MI.24026	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	78	26	I	M	atT/atA	3,63	1	0	probably_damaging	1	neutral	0,26	neutral	2,1	neutral	-1,66	deleterious	-2,79	medium_impact	3,1	damaging	0,25	damaging	0,2	deleterious	2,99	22,2	0,55	0,6	neutral	0,47	disease	0,62	disease	0,57	disease	0,72	4	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	-0,05	medium_impact	1,46	0,81	0,85	15,49	8,03	P	0,95	P	0,87	NA	NA	0,58	rs387906424	Pathogenic|Pathogenic	Leber_hereditary_optic_neuropathy_with_dystonia|Leber's_optic_atrophy	RCV000010329.2|RCV000055704.1	MedGen:OMIM|MedGen:OMIM:SNOMED_CT	.	.	.	.	A14596T	LHON	+	-	Reported	4
chrM	14596	14596	A	C	MI.24027	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	78	26	I	M	atT/atG	3,63	1	0	probably_damaging	1	neutral	0,26	neutral	2,1	neutral	-1,66	deleterious	-2,79	medium_impact	3,1	damaging	0,25	damaging	0,2	deleterious	2,88	21,8	0,55	0,6	neutral	0,47	disease	0,62	disease	0,57	disease	0,72	4	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	-0,05	medium_impact	1,46	0,81	0,85	15,49	8,03	P	0,94	P	0,87	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14597	14597	A	C	MI.24028	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	77	26	I	S	aTt/aGt	1,1	0,88	0	probably_damaging	1	neutral	0,37	neutral	2,04	neutral	-2,97	deleterious	-5,76	medium_impact	3,44	damaging	0,36	neutral	0,32	deleterious	3,61	23,2	0,39	0,5	disease	0,52	disease	0,86	disease	0,62	disease	0,8	6	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,82	low_impact	-3,55	medium_impact	0,08	medium_impact	1,74	0,56	0,8	15,49	8,03	P	0,64	P	0,97	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14597	14597	A	T	MI.24029	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	77	26	I	N	aTt/aAt	1,1	0,88	0	probably_damaging	1	neutral	0,25	neutral	2	deleterious	-4,74	deleterious	-6,75	medium_impact	3,1	damaging	0,39	neutral	0,36	deleterious	3,7	23,3	0,43	0,55	disease	0,66	disease	0,88	disease	0,65	disease	0,8	6	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,84	low_impact	-3,55	medium_impact	-0,06	medium_impact	1,46	0,59	0,8	15,49	8,03	P	0,58	P	0,99	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6146	6146	A	T	MI.2403	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	243	81	W	C	tgA/tgT	9,38	1	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,98	deleterious	-8,68	high_impact	4,96	damaging	0,56	damaging	0,04	deleterious	4,04	23,7	0,26	0,55	disease	0,62	disease	0,93	disease	0,75	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,31	0,9	2,92	6,8	P	0,63	P	0,88	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14597	14597	A	G	MI.24030	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	77	26	I	T	aTt/aCt	1,1	0,88	0	probably_damaging	1	neutral	0,3	neutral	2,04	neutral	-2,89	deleterious	-4,58	medium_impact	3,44	damaging	0,35	neutral	0,33	deleterious	3,08	22,5	0,45	0,55	neutral	0,48	disease	0,67	disease	0,62	disease	0,72	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,78	low_impact	-3,55	medium_impact	0	medium_impact	1,74	0,61	0,8	15,49	8,03	P	0,67	P	0,92	NA	NA	0,62	rs797045055	Likely pathogenic|Likely pathogenic	Dysarthria|Dystonia	RCV000191107.1|RCV000191107.1	Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen	.	.	.	.	.	.	.	.	.	.
chrM	14598	14598	T	G	MI.24031	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	76	26	I	L	Att/Ctt	1,56	0,8	0	probably_damaging	1	neutral	0,61	neutral	2,21	neutral	-0,63	neutral	-1,99	medium_impact	3,1	damaging	0,41	neutral	0,37	deleterious	2,35	18,5	0,39	0,5	neutral	0,24	disease	0,64	disease	0,58	disease	0,72	4	deleterious	0,99	neutral	0,31	deleterious	1	deleterious	0,7	low_impact	-3,55	medium_impact	0,31	medium_impact	1,46	0,68	0,85	15,49	8,03	P	0,65	P	0,62	NA	NA	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14598	14598	T	C	MI.24032	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	76	26	I	V	Att/Gtt	1,56	0,8	0	probably_damaging	1	neutral	0,45	neutral	2,37	neutral	0,22	neutral	-0,62	low_impact	1,71	neutral	0,79	neutral	0,84	neutral	-0,45	0,29	0,58	0,65	neutral	0,29	neutral	0,49	neutral	0,41	neutral	0,45	1	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,68	low_impact	-3,55	medium_impact	0,16	medium_impact	0,29	0,63	0,8	15,49	8,03	N	0,31	N	0,15	NA	NA	0,22	rs1057518882	Likely pathogenic|Likely pathogenic	Blindness|Parkinsonism	RCV000415203.1|RCV000415203.1	Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen	.	.	.	.	.	.	.	.	.	.
chrM	14598	14598	T	A	MI.24033	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	76	26	I	F	Att/Ttt	1,56	0,8	0	probably_damaging	1	neutral	0,59	neutral	2,1	neutral	-1,7	deleterious	-3,97	medium_impact	1,94	neutral	0,62	neutral	0,67	deleterious	4,16	23,8	0,51	0,6	neutral	0,15	disease	0,79	neutral	0,42	disease	0,58	2	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,7	low_impact	-3,55	medium_impact	0,29	medium_impact	0,49	0,78	0,85	15,49	8,03	N	0,31	N	0,93	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14600	14600	G	T	MI.24034	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	74	25	P	H	cCt/cAt	-0,96	0	0	probably_damaging	1	neutral	0,54	neutral	1,43	deleterious	-8,49	deleterious	-8,93	high_impact	4	damaging	0,51	damaging	0,05	deleterious	3,37	22,9	0,24	0,45	disease	0,93	disease	0,95	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,93	low_impact	-3,55	medium_impact	0,25	high_impact	2,21	0,64	0,8	10,18	13,06	N	0,4	N	0,73	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14600	14600	G	A	MI.24035	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	74	25	P	L	cCt/cTt	-0,96	0	0	probably_damaging	1	neutral	0,75	neutral	1,53	deleterious	-7,25	deleterious	-9,92	high_impact	4	damaging	0,53	damaging	0,07	deleterious	3,97	23,6	0,32	0,5	disease	0,86	disease	0,95	disease	0,7	disease	0,84	7	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,91	low_impact	-3,55	medium_impact	0,47	high_impact	2,21	0,74	0,85	10,18	13,06	N	0,38	N	0,96	NA	NA	0,82	.	.	.	.	.	.	.	.	.	G14600A	Leigh Disease/optic atrophy	+	+	Reported	3
chrM	14600	14600	G	C	MI.24036	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	74	25	P	R	cCt/cGt	-0,96	0	0	probably_damaging	1	neutral	0,35	neutral	1,44	deleterious	-7,4	deleterious	-8,93	high_impact	4	damaging	0,44	damaging	0,06	deleterious	3,15	22,6	0,22	0,45	disease	0,87	disease	0,96	disease	0,78	disease	0,9	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,55	medium_impact	0,06	high_impact	2,21	0,56	0,8	10,18	13,06	N	0,47	N	0,66	NA	NA	0,85	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14601	14601	G	A	MI.24037	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	73	25	P	S	Cct/Tct	2,25	0,98	0	probably_damaging	1	neutral	0,56	neutral	1,47	deleterious	-6,43	deleterious	-7,93	high_impact	4	damaging	0,5	damaging	0,08	deleterious	3,44	23	0,3	0,45	disease	0,78	disease	0,94	disease	0,66	disease	0,8	6	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0,27	high_impact	2,21	0,44	0,8	10,18	13,06	P	0,54	P	0,79	NA	NA	0,78	.	.	.	.	.	.	COSM1138278	.	.	.	.	.	.	.	.
chrM	14601	14601	G	T	MI.24038	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	73	25	P	T	Cct/Act	2,25	0,98	0	probably_damaging	1	neutral	0,39	neutral	1,49	deleterious	-6,87	deleterious	-7,93	high_impact	4	damaging	0,53	damaging	0,07	deleterious	3,08	22,5	0,26	0,45	disease	0,82	disease	0,93	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0,1	high_impact	2,21	0,71	0,85	10,18	13,06	P	0,54	P	0,88	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14601	14601	G	C	MI.24039	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	73	25	P	A	Cct/Gct	2,25	0,98	0	probably_damaging	1	neutral	0,52	neutral	1,49	deleterious	-6,16	deleterious	-7,93	high_impact	3,66	damaging	0,54	damaging	0,09	deleterious	2,66	20,6	0,23	0,45	disease	0,75	disease	0,89	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	0,23	medium_impact	1,93	0,73	0,85	10,18	13,06	N	0,5	N	0,71	NA	NA	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6147	6147	C	G	MI.2404	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	244	82	L	V	Cta/Gta	0,59	0,04	0	probably_damaging	0,98	deleterious	0	neutral	2,53	neutral	-1,42	neutral	-1,98	medium_impact	3,48	damaging	0,42	damaging	0,11	deleterious	3,35	22,9	0,33	0,55	neutral	0,31	disease	0,82	neutral	0,5	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,76	low_impact	-2,35	low_impact	-1,48	high_impact	2,11	0,75	0,9	1,36	7,02	N	0,44	N	0,66	polymorphism	0,98	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14603	14603	G	C	MI.24040	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	71	24	S	C	tCt/tGt	-4,17	0	0	probably_damaging	1	neutral	0,18	neutral	2,08	deleterious	-5,77	deleterious	-4,98	high_impact	3,94	neutral	0,64	damaging	0,02	deleterious	3,18	22,7	0,38	0,5	disease	0,75	disease	0,91	disease	0,75	disease	0,83	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	-0,16	high_impact	2,16	0,7	0,85	18,14	17,22	N	0,32	N	0,99	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14603	14603	G	A	MI.24041	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	71	24	S	F	tCt/tTt	-4,17	0	0	probably_damaging	1	neutral	0,71	neutral	2,09	deleterious	-6,13	deleterious	-5,97	high_impact	3,6	neutral	0,66	damaging	0,03	deleterious	3,78	23,4	0,28	0,45	disease	0,82	disease	0,95	disease	0,77	disease	0,9	8	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	0,42	medium_impact	1,88	0,49	0,8	18,14	17,22	N	0,32	N	0,98	NA	NA	0,8	.	.	.	.	.	pancreatic cancer cell line xenograft	COSM1155563	.	.	.	.	.	.	.	.
chrM	14603	14603	G	T	MI.24042	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	71	24	S	Y	tCt/tAt	-4,17	0	0	probably_damaging	1	neutral	1	neutral	2,1	deleterious	-6,34	deleterious	-5,97	high_impact	3,94	neutral	0,62	damaging	0,02	deleterious	3,5	23,1	0,28	0,45	disease	0,84	disease	0,95	disease	0,78	disease	0,9	8	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,9	low_impact	-3,55	high_impact	1,87	high_impact	2,16	0,59	0,8	18,14	17,22	N	0,35	N	0,98	NA	NA	0,8	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14604	14604	A	T	MI.24043	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	70	24	S	T	Tct/Act	2,25	0,1	0	probably_damaging	1	neutral	0,39	neutral	2,16	deleterious	-3,64	deleterious	-2,98	medium_impact	3,25	neutral	0,68	damaging	0,25	deleterious	3,11	22,5	0,33	0,5	neutral	0,46	disease	0,82	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,82	low_impact	-3,55	medium_impact	0,1	medium_impact	1,58	0,81	0,85	18,14	17,22	N	0,38	N	0,69	NA	NA	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14604	14604	A	G	MI.24044	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	70	24	S	P	Tct/Cct	2,25	0,1	0	probably_damaging	1	neutral	0,22	neutral	2,1	deleterious	-5,1	deleterious	-4,98	high_impact	3,94	neutral	0,63	damaging	0,04	deleterious	3,82	23,4	0,24	0,45	disease	0,67	disease	0,94	disease	0,75	disease	0,9	8	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,55	medium_impact	-0,1	high_impact	2,16	0,64	0,8	18,14	17,22	N	0,43	N	0,98	NA	NA	0,82	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14604	14604	A	C	MI.24045	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	70	24	S	A	Tct/Gct	2,25	0,1	0	probably_damaging	1	neutral	0,52	neutral	2,15	neutral	-2,06	deleterious	-2,98	medium_impact	2,26	neutral	0,69	damaging	0,2	deleterious	3,06	22,4	0,37	0,5	neutral	0,19	disease	0,63	disease	0,62	neutral	0,43	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,74	low_impact	-3,55	medium_impact	0,23	medium_impact	0,75	0,7	0,85	18,14	17,22	N	0,3	N	0,48	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14606	14606	G	A	MI.24046	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	68	23	P	L	cCt/cTt	-9,22	0	0	probably_damaging	1	neutral	0,76	neutral	2,45	neutral	-2,81	deleterious	-9,98	medium_impact	3,29	neutral	0,61	damaging	0,04	deleterious	4,02	23,6	0,39	0,5	disease	0,86	disease	0,94	disease	0,68	disease	0,81	6	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,89	low_impact	-3,55	medium_impact	0,48	medium_impact	1,62	0,93	0,95	19,03	10,37	N	0,23	N	0,96	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14606	14606	G	T	MI.24047	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	68	23	P	H	cCt/cAt	-9,22	0	0	probably_damaging	1	neutral	0,48	neutral	2,31	deleterious	-5,68	deleterious	-8,98	high_impact	3,98	neutral	0,65	damaging	0,02	deleterious	3,4	23	0,4	0,5	disease	0,93	disease	0,94	disease	0,75	disease	0,84	7	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,9	low_impact	-3,55	medium_impact	0,19	high_impact	2,19	0,71	0,85	19,03	10,37	N	0,35	N	0,73	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14606	14606	G	C	MI.24048	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	68	23	P	R	cCt/cGt	-9,22	0	0	probably_damaging	1	neutral	0,28	neutral	2,41	deleterious	-4,48	deleterious	-8,98	medium_impact	3,44	neutral	0,63	damaging	0,03	deleterious	3,22	22,7	0,39	0,5	disease	0,87	disease	0,95	disease	0,74	disease	0,85	7	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,9	low_impact	-3,55	medium_impact	-0,02	medium_impact	1,74	0,77	0,85	19,03	10,37	N	0,36	N	0,66	NA	NA	0,78	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14607	14607	G	C	MI.24049	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	67	23	P	A	Cct/Gct	5	1	0	probably_damaging	1	neutral	0,47	neutral	2,32	deleterious	-3,5	deleterious	-7,99	high_impact	3,98	neutral	0,66	damaging	0,05	deleterious	2,61	20,3	0,37	0,5	disease	0,75	disease	0,86	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,86	low_impact	-3,55	medium_impact	0,18	high_impact	2,19	0,79	0,85	19,03	10,37	P	0,59	P	0,71	NA	NA	0,84	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6147	6147	C	A	MI.2405	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	244	82	L	M	Cta/Ata	0,59	0,04	0	probably_damaging	1	neutral	0,21	neutral	2,42	neutral	-2,55	neutral	-1,24	medium_impact	2,29	damaging	0,58	damaging	0,14	deleterious	3,61	23,2	0,29	0,55	disease	0,59	disease	0,61	neutral	0,18	neutral	0,46	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,75	low_impact	-3,58	medium_impact	-0,13	medium_impact	1,02	0,74	0,9	1,36	7,02	N	0,44	N	0,59	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14607	14607	G	A	MI.24050	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	67	23	P	S	Cct/Tct	5	1	0	probably_damaging	1	neutral	0,48	neutral	2,4	deleterious	-3,78	deleterious	-7,99	medium_impact	3,29	neutral	0,66	damaging	0,05	deleterious	3,5	23,1	0,4	0,5	disease	0,78	disease	0,91	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,87	low_impact	-3,55	medium_impact	0,19	medium_impact	1,62	0,28	0,8	19,03	10,37	N	0,51	P	0,79	NA	NA	0,69	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14607	14607	G	T	MI.24051	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	67	23	P	T	Cct/Act	5	1	0	probably_damaging	1	neutral	0,35	neutral	2,34	deleterious	-4,09	deleterious	-7,99	high_impact	3,98	neutral	0,65	damaging	0,03	deleterious	3,07	22,4	0,37	0,5	disease	0,82	disease	0,91	disease	0,71	disease	0,79	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,55	medium_impact	0,06	high_impact	2,19	0,78	0,85	19,03	10,37	P	0,6	P	0,88	NA	NA	0,83	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14608	14608	C	A	MI.24052	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	66	22	K	N	aaG/aaT	2,71	1	0	probably_damaging	1	neutral	0,58	neutral	2,49	neutral	-0,07	deleterious	-4,99	low_impact	1,12	neutral	0,71	neutral	0,44	deleterious	4,31	24	0,63	0,7	neutral	0,14	neutral	0,29	neutral	0,47	neutral	0,4	2	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,69	low_impact	-3,55	medium_impact	0,28	medium_impact	-0,2	0,68	0,85	25,22	20,33	N	0,44	N	0,67	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14608	14608	C	G	MI.24053	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	66	22	K	N	aaG/aaC	2,71	1	0	probably_damaging	1	neutral	0,58	neutral	2,49	neutral	-0,07	deleterious	-4,99	low_impact	1,12	neutral	0,71	neutral	0,44	deleterious	4,08	23,7	0,63	0,7	neutral	0,14	neutral	0,29	neutral	0,47	neutral	0,4	2	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,69	low_impact	-3,55	medium_impact	0,28	medium_impact	-0,2	0,68	0,85	25,22	20,33	N	0,45	N	0,67	NA	NA	0,54	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14609	14609	T	A	MI.24054	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	65	22	K	M	aAg/aTg	-1,42	0	0	probably_damaging	1	neutral	0,28	neutral	2,19	deleterious	-4,11	deleterious	-5,99	high_impact	3,58	neutral	0,77	damaging	0,2	deleterious	4,11	23,7	0,3	0,45	disease	0,72	disease	0,77	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,83	low_impact	-3,55	medium_impact	-0,02	medium_impact	1,86	0,49	0,8	25,22	20,33	N	0,3	N	0,43	NA	NA	0,64	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14609	14609	T	G	MI.24055	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	65	22	K	T	aAg/aCg	-1,42	0	0	probably_damaging	1	neutral	0,45	neutral	2,24	neutral	-2,26	deleterious	-5,99	high_impact	3,58	neutral	0,79	damaging	0,2	deleterious	3,83	23,4	0,26	0,45	neutral	0,46	disease	0,76	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,82	low_impact	-3,55	medium_impact	0,16	medium_impact	1,86	0,51	0,8	25,22	20,33	N	0,27	N	0,76	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14610	14610	T	G	MI.24056	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	64	22	K	Q	Aag/Cag	1,1	0,57	0	probably_damaging	1	neutral	0,31	neutral	2,24	neutral	-1,95	deleterious	-3,99	high_impact	3,58	neutral	0,78	damaging	0,2	deleterious	3,62	23,2	0,39	0,5	neutral	0,38	disease	0,73	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,55	medium_impact	0,01	medium_impact	1,86	0,69	0,85	25,22	20,33	N	0,32	N	0,86	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14610	14610	T	C	MI.24057	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	64	22	K	E	Aag/Gag	1,1	0,57	0	probably_damaging	1	neutral	0,27	neutral	2,27	neutral	-1,32	deleterious	-3,99	high_impact	3,58	neutral	0,75	damaging	0,19	deleterious	3,76	23,3	0,32	0,5	neutral	0,32	disease	0,89	disease	0,76	disease	0,82	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-3,55	medium_impact	-0,03	medium_impact	1,86	0,7	0,85	25,22	20,33	N	0,43	N	0,89	NA	NA	0,63	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14612	14612	G	T	MI.24058	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	62	21	S	Y	tCt/tAt	-4,17	0	0	probably_damaging	1	neutral	1	neutral	1,93	neutral	-1,54	deleterious	-4,68	high_impact	3,54	neutral	0,71	damaging	0,12	deleterious	3,34	22,9	0,23	0,45	disease	0,67	disease	0,93	disease	0,68	disease	0,8	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,84	low_impact	-3,55	high_impact	1,87	medium_impact	1,83	0,7	0,85	22,57	20,88	N	0,23	N	0,86	NA	NA	0,79	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14612	14612	G	A	MI.24059	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	62	21	S	F	tCt/tTt	-4,17	0	0	probably_damaging	1	neutral	0,72	neutral	1,96	neutral	0,53	deleterious	-4,57	high_impact	3,88	neutral	0,68	damaging	0,11	deleterious	3,66	23,2	0,28	0,45	disease	0,63	disease	0,93	disease	0,68	disease	0,8	6	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,83	low_impact	-3,55	medium_impact	0,43	high_impact	2,11	0,5	0,8	22,57	20,88	N	0,22	N	0,83	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6148	6148	T	A	MI.2406	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	245	82	L	Q	cTa/cAa	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	2,35	deleterious	-5,03	deleterious	-3,99	high_impact	5	damaging	0,51	damaging	0,08	deleterious	4,28	24	0,12	0,55	disease	0,73	disease	0,87	disease	0,52	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,7	0,9	1,36	7,02	P	0,59	P	0,82	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14612	14612	G	C	MI.24060	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	62	21	S	C	tCt/tGt	-4,17	0	0	probably_damaging	1	neutral	0,18	neutral	1,92	neutral	-2,34	deleterious	-3,82	medium_impact	2,79	neutral	0,84	neutral	0,34	neutral	1,11	11,26	0,4	0,5	disease	0,7	disease	0,86	disease	0,52	disease	0,56	1	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,81	low_impact	-3,55	medium_impact	-0,16	medium_impact	1,2	0,76	0,85	22,57	20,88	N	0,31	N	0,55	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14613	14613	A	T	MI.24061	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	61	21	S	T	Tct/Act	1,1	0	0	probably_damaging	1	neutral	0,4	neutral	2	neutral	1,05	neutral	-2,15	medium_impact	3,19	neutral	0,82	neutral	0,77	neutral	1,65	14,15	0,28	0,45	neutral	0,23	disease	0,81	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,74	low_impact	-3,55	medium_impact	0,11	medium_impact	1,53	0,82	0,85	22,57	20,88	N	0,34	N	0,17	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14613	14613	A	C	MI.24062	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	61	21	S	A	Tct/Gct	1,1	0	0	probably_damaging	1	neutral	0,53	neutral	2,07	neutral	-0,64	neutral	-2,04	medium_impact	2,79	neutral	0,81	neutral	0,33	deleterious	0,2	4,64	0,37	0,5	neutral	0,3	disease	0,77	disease	0,53	disease	0,55	1	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	0,24	medium_impact	1,2	0,73	0,85	22,57	20,88	N	0,22	N	0,2	NA	NA	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14613	14613	A	G	MI.24063	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	61	21	S	P	Tct/Cct	1,1	0	0	probably_damaging	1	neutral	0,24	neutral	1,92	deleterious	-3,5	deleterious	-4,13	high_impact	3,88	neutral	0,67	damaging	0,12	deleterious	3,7	23,3	0,25	0,45	disease	0,61	disease	0,92	disease	0,65	disease	0,76	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,84	low_impact	-3,55	medium_impact	-0,07	high_impact	2,11	0,73	0,85	22,57	20,88	N	0,33	N	0,83	NA	NA	0,75	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14615	14615	G	A	MI.24064	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	59	20	S	F	tCt/tTt	-0,96	0	0	probably_damaging	0,98	neutral	0,6	neutral	2,36	deleterious	-4,51	deleterious	-5,74	medium_impact	2,84	neutral	0,76	neutral	0,51	deleterious	3,76	23,3	0,25	0,45	disease	0,77	disease	0,9	disease	0,75	disease	0,83	7	neutral	0,98	neutral	0,31	deleterious	1	deleterious	0,85	low_impact	-2,35	medium_impact	0,3	medium_impact	1,24	0,65	0,8	24,78	23,03	N	0,28	N	0,98	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14615	14615	G	C	MI.24065	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	59	20	S	C	tCt/tGt	-0,96	0	0	benign	0,19	neutral	0,16	neutral	2,21	deleterious	-4,22	deleterious	-4,58	medium_impact	2,35	neutral	0,88	neutral	0,63	deleterious	3,05	22,4	0,25	0,45	disease	0,69	disease	0,87	disease	0,68	disease	0,8	6	neutral	0,81	deleterious	0,49	neutral	-3	deleterious	0,46	medium_impact	-0,22	medium_impact	-0,19	medium_impact	0,83	0,73	0,85	24,78	23,03	N	0,4	N	0,63	NA	NA	0,57	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14615	14615	G	T	MI.24066	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	59	20	S	Y	tCt/tAt	-0,96	0	0	probably_damaging	0,99	neutral	0,78	neutral	2,23	deleterious	-4,74	deleterious	-5,73	medium_impact	3,38	neutral	0,77	neutral	0,57	deleterious	3,4	23	0,23	0,45	disease	0,8	disease	0,88	disease	0,76	disease	0,86	7	deleterious	0,98	neutral	0,4	deleterious	1	deleterious	0,86	low_impact	-2,63	medium_impact	0,51	medium_impact	1,69	0,75	0,85	24,78	23,03	N	0,31	N	0,96	NA	NA	0,73	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14616	14616	A	C	MI.24067	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	58	20	S	A	Tct/Gct	3,4	0,46	0	possibly_damaging	0,67	neutral	1	neutral	2,27	neutral	0,94	deleterious	-2,57	neutral_impact	0,5	neutral	0,9	neutral	0,95	neutral	1,52	13,4	0,38	0,5	neutral	0,1	neutral	0,19	neutral	0,42	neutral	0,33	3	neutral	0,67	deleterious	0,67	neutral	-3	deleterious	0,57	low_impact	-1,08	high_impact	1,87	medium_impact	-0,72	0,81	0,85	24,78	23,03	N	0,36	N	0,14	NA	NA	0,52	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14616	14616	A	T	MI.24068	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	58	20	S	T	Tct/Act	3,4	0,46	0	possibly_damaging	0,86	neutral	0,35	neutral	2,43	neutral	-2,09	deleterious	-2,83	medium_impact	3,04	neutral	0,76	neutral	0,57	deleterious	2,97	22,1	0,27	0,45	neutral	0,39	disease	0,67	disease	0,73	disease	0,75	5	neutral	0,88	neutral	0,25	NA	0	deleterious	0,74	low_impact	-1,52	medium_impact	0,06	medium_impact	1,41	0,75	0,85	24,78	23,03	N	0,4	N	0,54	NA	NA	0,58	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14616	14616	A	G	MI.24069	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	58	20	S	P	Tct/Cct	3,4	0,46	0	probably_damaging	0,98	neutral	0,24	neutral	2,2	deleterious	-3,58	deleterious	-4,71	medium_impact	3,38	neutral	0,85	neutral	0,52	deleterious	3,58	23,2	0,21	0,45	disease	0,61	disease	0,93	disease	0,73	disease	0,86	7	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,87	low_impact	-2,35	medium_impact	-0,07	medium_impact	1,69	0,78	0,85	24,78	23,03	N	0,35	N	0,94	NA	NA	0,72	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6148	6148	T	G	MI.2407	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	245	82	L	R	cTa/cGa	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	2,35	deleterious	-4,87	deleterious	-4,01	high_impact	5	damaging	0,5	damaging	0,07	deleterious	4,13	23,8	0,1	0,55	disease	0,71	disease	0,95	disease	0,66	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,44	0,9	1,36	7,02	P	0,58	P	0,9	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14617	14617	A	T	MI.24070	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	57	19	F	L	ttT/ttA	-0,04	0	0	probably_damaging	1	neutral	0,53	neutral	2,68	neutral	-2,82	deleterious	-4,12	medium_impact	2,07	neutral	0,86	neutral	0,83	deleterious	2,79	21,3	0,52	0,6	neutral	0,09	disease	0,68	neutral	0,44	disease	0,55	1	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,69	low_impact	-3,55	medium_impact	0,24	medium_impact	0,59	0,86	0,9	29,65	29,28	N	0,27	N	0,4	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14617	14617	A	C	MI.24071	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	57	19	F	L	ttT/ttG	-0,04	0	0	probably_damaging	1	neutral	0,53	neutral	2,68	neutral	-2,82	deleterious	-4,12	medium_impact	2,07	neutral	0,86	neutral	0,83	deleterious	2,66	20,6	0,52	0,6	neutral	0,09	disease	0,68	neutral	0,44	disease	0,55	1	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,69	low_impact	-3,55	medium_impact	0,24	medium_impact	0,59	0,86	0,9	29,65	29,28	N	0,27	N	0,4	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14618	14618	A	C	MI.24072	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	56	19	F	C	tTt/tGt	-0,96	0	0	probably_damaging	1	neutral	0,09	neutral	2,27	deleterious	-5,3	deleterious	-6,34	medium_impact	3,39	neutral	0,8	damaging	0,18	deleterious	3,48	23,1	0,31	0,5	disease	0,65	disease	0,88	disease	0,66	disease	0,81	6	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,83	low_impact	-3,55	medium_impact	-0,35	medium_impact	1,7	0,46	0,8	29,65	29,28	N	0,32	N	0,81	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14618	14618	A	T	MI.24073	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	56	19	F	Y	tTt/tAt	-0,96	0	0	probably_damaging	1	neutral	0,51	neutral	2,27	deleterious	-3,08	neutral	-2,48	medium_impact	3,39	neutral	0,78	damaging	0,21	deleterious	3,55	23,1	0,31	0,45	disease	0,53	disease	0,75	disease	0,65	disease	0,73	5	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,8	low_impact	-3,55	medium_impact	0,22	medium_impact	1,7	0,73	0,85	29,65	29,28	N	0,25	N	0,76	NA	NA	0,59	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14618	14618	A	G	MI.24074	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	56	19	F	S	tTt/tCt	-0,96	0	0	probably_damaging	1	neutral	0,36	neutral	2,29	neutral	-0,41	deleterious	-6,42	medium_impact	3,39	neutral	0,78	neutral	0,3	deleterious	4,07	23,7	0,3	0,45	disease	0,51	disease	0,82	disease	0,62	disease	0,78	6	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,82	low_impact	-3,55	medium_impact	0,07	medium_impact	1,7	0,61	0,8	29,65	29,28	N	0,29	N	0,92	NA	NA	0,6	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14619	14619	A	T	MI.24075	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	55	19	F	I	Ttt/Att	2,48	0,05	0	probably_damaging	1	neutral	0,33	neutral	2,51	deleterious	-3,41	deleterious	-4,16	medium_impact	2,84	neutral	0,76	neutral	0,49	deleterious	2,68	20,7	0,34	0,5	neutral	0,15	disease	0,74	neutral	0,47	disease	0,59	2	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,71	low_impact	-3,55	medium_impact	0,04	medium_impact	1,24	0,71	0,85	29,65	29,28	N	0,42	N	0,79	NA	NA	0,55	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14619	14619	A	C	MI.24076	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	55	19	F	V	Ttt/Gtt	2,48	0,05	0	probably_damaging	1	neutral	1	neutral	2,49	deleterious	-3,06	deleterious	-5	neutral_impact	0,49	neutral	0,84	neutral	0,9	deleterious	2,03	16,38	0,35	0,5	neutral	0,12	neutral	0,38	neutral	0,43	neutral	0,44	1	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,66	low_impact	-3,55	high_impact	1,87	medium_impact	-0,73	0,73	0,85	29,65	29,28	N	0,29	N	0,81	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14619	14619	A	G	MI.24077	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	55	19	F	L	Ttt/Ctt	2,48	0,05	0	probably_damaging	1	neutral	0,53	neutral	2,68	neutral	-2,82	deleterious	-4,12	medium_impact	2,07	neutral	0,86	neutral	0,83	deleterious	2,72	20,9	0,52	0,6	neutral	0,09	disease	0,68	neutral	0,44	disease	0,55	1	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,69	low_impact	-3,55	medium_impact	0,24	medium_impact	0,59	0,86	0,9	29,65	29,28	N	0,31	N	0,4	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14621	14621	C	A	MI.24078	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	53	18	G	V	gGg/gTg	-11,97	0	0	probably_damaging	1	neutral	0,58	neutral	2,57	neutral	1,06	deleterious	-7,2	medium_impact	2,06	neutral	0,78	neutral	0,42	deleterious	3,09	22,5	0,36	0,5	neutral	0,24	disease	0,85	neutral	0,46	disease	0,6	2	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	0,28	medium_impact	0,59	0,8	0,85	21,24	15,57	N	0,27	N	0,94	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14621	14621	C	T	MI.24079	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	53	18	G	E	gGg/gAg	-11,97	0	0	probably_damaging	1	neutral	0,27	neutral	2,32	neutral	-2,53	deleterious	-6,15	high_impact	3,6	neutral	0,76	damaging	0,15	deleterious	3,94	23,5	0,38	0,5	disease	0,52	disease	0,85	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-3,55	medium_impact	-0,03	medium_impact	1,88	0,87	0,9	21,24	15,57	N	0,31	N	0,95	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6148	6148	T	C	MI.2408	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	245	82	L	P	cTa/cCa	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	2,34	deleterious	-5,43	deleterious	-4,7	high_impact	5	damaging	0,42	damaging	0,08	deleterious	3,85	23,4	0,12	0,55	disease	0,78	disease	0,91	disease	0,65	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,7	0,9	1,36	7,02	P	0,54	P	0,83	disease_causing	0,58	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14621	14621	C	G	MI.24080	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	53	18	G	A	gGg/gCg	-11,97	0	0	probably_damaging	1	neutral	0,58	neutral	2,46	neutral	0,62	deleterious	-4,27	low_impact	1,34	neutral	0,81	neutral	0,81	deleterious	1,98	16,1	0,59	0,65	neutral	0,13	neutral	0,2	neutral	0,28	neutral	0,34	3	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,66	low_impact	-3,55	medium_impact	0,28	medium_impact	-0,02	0,9	0,95	21,24	15,57	N	0,3	N	0,52	NA	NA	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14622	14622	C	A	MI.24081	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	52	18	G	W	Ggg/Tgg	0,18	0	0	probably_damaging	1	neutral	0,18	neutral	2,32	deleterious	-3,55	deleterious	-6,68	medium_impact	3,05	neutral	0,77	damaging	0,2	deleterious	4,7	24,6	0,26	0,45	disease	0,88	disease	0,87	disease	0,68	disease	0,81	6	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,87	low_impact	-3,55	medium_impact	-0,16	medium_impact	1,42	0,65	0,8	21,24	15,57	N	0,27	N	0,95	NA	NA	0,65	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14622	14622	C	G	MI.24082	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	52	18	G	R	Ggg/Cgg	0,18	0	0	probably_damaging	1	neutral	0,35	neutral	2,32	neutral	-1,72	deleterious	-6,31	high_impact	3,6	neutral	0,76	damaging	0,15	deleterious	4,01	23,6	0,3	0,45	disease	0,58	disease	0,88	disease	0,73	disease	0,83	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-3,55	medium_impact	0,06	medium_impact	1,88	0,89	0,9	21,24	15,57	N	0,31	N	0,98	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14624	14624	A	T	MI.24083	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	50	17	V	E	gTg/gAg	-20	0	0	probably_damaging	0,96	neutral	0,11	neutral	2,17	deleterious	-6,25	deleterious	-5,49	high_impact	3,6	neutral	0,8	neutral	0,37	deleterious	4,18	23,8	0,17	0,45	disease	0,8	disease	0,77	disease	0,78	disease	0,83	7	deleterious	0,98	neutral	0,08	deleterious	2	deleterious	0,82	low_impact	-2,06	medium_impact	-0,3	medium_impact	1,88	0,79	0,85	28,76	21,22	N	0,38	N	0,95	NA	NA	0,74	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14624	14624	A	C	MI.24084	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	50	17	V	G	gTg/gGg	-20	0	0	probably_damaging	0,94	neutral	0,22	neutral	2,24	deleterious	-6,33	deleterious	-6,46	high_impact	3,6	neutral	0,81	neutral	0,51	deleterious	3,09	22,5	0,23	0,45	disease	0,81	disease	0,65	disease	0,67	disease	0,73	5	neutral	0,96	neutral	0,14	deleterious	2	deleterious	0,77	low_impact	-1,89	medium_impact	-0,1	medium_impact	1,88	0,75	0,85	28,76	21,22	N	0,39	N	0,91	NA	NA	0,66	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14624	14624	A	G	MI.24085	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	50	17	V	A	gTg/gCg	-20	0	0	possibly_damaging	0,58	neutral	0,34	neutral	2,28	deleterious	-4,25	deleterious	-3,53	medium_impact	2,22	neutral	0,91	neutral	0,84	deleterious	0,56	7,85	0,48	0,55	disease	0,51	neutral	0,36	disease	0,52	neutral	0,47	1	neutral	0,67	neutral	0,38	NA	0	deleterious	0,55	medium_impact	-0,92	medium_impact	0,05	medium_impact	0,72	0,81	0,85	28,76	21,22	N	0,52	P	0,75	NA	NA	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14625	14625	C	G	MI.24086	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	49	17	V	L	Gtg/Ctg	3,17	0,17	0	possibly_damaging	0,45	neutral	1	neutral	2,66	neutral	-2,48	neutral	-1,62	low_impact	1,49	neutral	0,91	neutral	0,86	deleterious	0,31	5,74	0,47	0,55	neutral	0,17	neutral	0,27	neutral	0,42	neutral	0,44	1	neutral	0,45	deleterious	0,78	neutral	-3	neutral	0,28	medium_impact	-0,72	high_impact	1,87	medium_impact	0,11	0,9	0,95	28,76	21,22	N	0,34	N	0,5	NA	NA	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14625	14625	C	A	MI.24087	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	49	17	V	L	Gtg/Ttg	3,17	0,17	0	possibly_damaging	0,45	neutral	1	neutral	2,66	neutral	-2,48	neutral	-1,62	low_impact	1,49	neutral	0,91	neutral	0,86	deleterious	0,67	8,66	0,47	0,55	neutral	0,17	neutral	0,27	neutral	0,42	neutral	0,44	1	neutral	0,45	deleterious	0,78	neutral	-3	neutral	0,28	medium_impact	-0,72	high_impact	1,87	medium_impact	0,11	0,9	0,95	28,76	21,22	N	0,34	N	0,5	NA	NA	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14625	14625	C	T	MI.24088	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	49	17	V	M	Gtg/Atg	3,17	0,17	0	benign	0,33	neutral	0,38	neutral	2,27	neutral	-2,91	neutral	-1,82	medium_impact	1,98	neutral	0,88	neutral	0,8	deleterious	0,83	9,63	0,61	0,65	disease	0,53	neutral	0,36	neutral	0,43	neutral	0,42	2	neutral	0,55	deleterious	0,53	neutral	-3	neutral	0,31	medium_impact	-0,51	medium_impact	0,09	medium_impact	0,52	0,94	0,95	28,76	21,22	N	0,44	N	0,66	NA	NA	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14626	14626	A	C	MI.24089	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	48	16	F	L	ttT/ttG	-2,11	0	0	probably_damaging	1	neutral	1	neutral	2,4	neutral	1,1	deleterious	-5,2	low_impact	1,37	neutral	0,88	neutral	0,89	deleterious	2,58	20,1	0,44	0,55	neutral	0,11	neutral	0,16	neutral	0,32	neutral	0,24	5	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,65	low_impact	-3,55	high_impact	1,87	medium_impact	0,01	0,75	0,85	17,26	11,64	N	0,31	N	0,75	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6150	6150	G	A	MI.2409	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	247	83	V	I	Gtt/Att	-2,88	0	0	benign	0	neutral	0,45	neutral	2,74	neutral	-0,26	neutral	-0,23	neutral_impact	0,56	neutral	0,74	neutral	0,9	deleterious	2,08	16,71	0,35	0,55	neutral	0,32	neutral	0,41	neutral	0,18	neutral	0,44	1	neutral	0,55	deleterious	0,73	neutral	-6	neutral	0,17	high_impact	2,07	medium_impact	0,14	medium_impact	-0,58	0,88	0,9	10,14	12,66	N	0,56	P	0,24	polymorphism	1	0,02	rs879053914	.	.	.	.	.	.	.	7,27	G6150A	Prostate Cancer/enriched in POAG cohort	+	-	Reported	2
chrM	14626	14626	A	T	MI.24090	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	48	16	F	L	ttT/ttA	-2,11	0	0	probably_damaging	1	neutral	1	neutral	2,4	neutral	1,1	deleterious	-5,2	low_impact	1,37	neutral	0,88	neutral	0,89	deleterious	2,66	20,6	0,44	0,55	neutral	0,11	neutral	0,16	neutral	0,32	neutral	0,24	5	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,65	low_impact	-3,55	high_impact	1,87	medium_impact	0,01	0,75	0,85	17,26	11,64	N	0,36	N	0,75	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14627	14627	A	T	MI.24091	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	47	16	F	Y	tTt/tAt	-0,96	0	0	probably_damaging	1	neutral	0,73	neutral	2,09	neutral	-0,76	deleterious	-2,68	medium_impact	3,22	neutral	0,86	neutral	0,58	deleterious	3,71	23,3	0,35	0,5	neutral	0,41	neutral	0,48	disease	0,55	disease	0,59	2	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,72	low_impact	-3,55	medium_impact	0,45	medium_impact	1,56	0,67	0,85	17,26	11,64	N	0,35	N	0,71	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14627	14627	A	G	MI.24092	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	47	16	F	S	tTt/tCt	-0,96	0	0	probably_damaging	1	neutral	0,57	neutral	2,09	neutral	2,7	deleterious	-7,03	medium_impact	2,6	neutral	0,86	neutral	0,77	deleterious	4,2	23,9	0,47	0,55	neutral	0,35	disease	0,6	disease	0,56	disease	0,64	3	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,73	low_impact	-3,55	medium_impact	0,27	medium_impact	1,04	0,65	0,8	17,26	11,64	N	0,31	N	0,94	NA	NA	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14627	14627	A	C	MI.24093	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	47	16	F	C	tTt/tGt	-0,96	0	0	probably_damaging	1	neutral	0,17	neutral	2,07	neutral	-0,87	deleterious	-6,05	medium_impact	2,6	neutral	0,89	neutral	0,76	deleterious	2,34	18,45	0,29	0,45	neutral	0,25	disease	0,7	neutral	0,49	disease	0,54	1	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,69	low_impact	-3,55	medium_impact	-0,18	medium_impact	1,04	0,46	0,8	17,26	11,64	N	0,44	N	0,49	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14628	14628	A	T	MI.24094	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	46	16	F	I	Ttt/Att	2,94	0,02	0	probably_damaging	1	neutral	0,59	neutral	2,26	neutral	0,4	deleterious	-5,21	medium_impact	2,67	neutral	0,85	neutral	0,67	deleterious	3,78	23,4	0,3	0,45	neutral	0,18	neutral	0,5	neutral	0,46	neutral	0,49	0	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,68	low_impact	-3,55	medium_impact	0,29	medium_impact	1,1	0,68	0,85	17,26	11,64	N	0,29	N	0,81	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14628	14628	A	G	MI.24095	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	46	16	F	L	Ttt/Ctt	2,94	0,02	0	probably_damaging	1	neutral	1	neutral	2,4	neutral	1,1	deleterious	-5,2	low_impact	1,37	neutral	0,88	neutral	0,89	deleterious	2,92	21,9	0,44	0,55	neutral	0,11	neutral	0,16	neutral	0,32	neutral	0,24	5	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,65	low_impact	-3,55	high_impact	1,87	medium_impact	0,01	0,75	0,85	17,26	11,64	N	0,34	N	0,75	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14628	14628	A	C	MI.24096	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	46	16	F	V	Ttt/Gtt	2,94	0,02	0	probably_damaging	1	neutral	0,6	neutral	2,29	neutral	0,95	deleterious	-6,11	medium_impact	2,12	neutral	0,85	neutral	0,77	deleterious	3,49	23,1	0,34	0,5	neutral	0,14	disease	0,59	neutral	0,43	neutral	0,47	1	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,67	low_impact	-3,55	medium_impact	0,3	medium_impact	0,64	0,72	0,85	17,26	11,64	N	0,28	N	0,89	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14630	14630	C	T	MI.24097	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	44	15	G	E	gGg/gAg	-7,38	0	0	probably_damaging	0,99	neutral	0,27	neutral	2,14	deleterious	-4,56	deleterious	-6,28	high_impact	3,84	damaging	0,57	damaging	0,17	deleterious	3,95	23,6	0,3	0,45	disease	0,59	disease	0,84	disease	0,78	disease	0,81	6	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-2,63	medium_impact	-0,03	high_impact	2,08	0,83	0,9	11,5	26,27	N	0,39	N	0,92	NA	NA	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14630	14630	C	G	MI.24098	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	44	15	G	A	gGg/gCg	-7,38	0	0	probably_damaging	0,93	neutral	0,51	neutral	2,31	deleterious	-3,13	deleterious	-4,42	medium_impact	3,29	neutral	0,67	neutral	0,37	deleterious	3,18	22,7	0,46	0,55	neutral	0,33	disease	0,69	disease	0,65	disease	0,62	2	neutral	0,92	neutral	0,29	deleterious	1	deleterious	0,74	low_impact	-1,83	medium_impact	0,22	medium_impact	1,62	0,83	0,85	11,5	26,27	N	0,31	N	0,75	NA	NA	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14630	14630	C	A	MI.24099	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	44	15	G	V	gGg/gTg	-7,38	0	0	probably_damaging	0,99	neutral	0,51	neutral	2,24	deleterious	-3,55	deleterious	-7,36	high_impact	3,84	damaging	0,47	damaging	0,21	deleterious	4,19	23,8	0,25	0,45	neutral	0,3	disease	0,87	disease	0,7	disease	0,79	6	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,78	low_impact	-2,63	medium_impact	0,22	high_impact	2,08	0,83	0,9	11,5	26,27	N	0,38	N	0,99	NA	NA	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8639	8639	T	A	MI.241	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	113	38	I	N	aTc/aAc	-3,8	0	0	probably_damaging	1	neutral	0,13	neutral	4,26	neutral	-2	deleterious	-4,58	medium_impact	2,73	neutral	0,87	neutral	0,59	deleterious	4,28	24	0,46	0,65	disease	0,76	disease	0,73	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	-0,18	medium_impact	1,24	0,51	0,9	15,49	18,25	N	0,36	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6150	6150	G	T	MI.2410	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	247	83	V	F	Gtt/Ttt	-2,88	0	0	possibly_damaging	0,69	deleterious	0	neutral	2,52	neutral	-2,37	deleterious	-2,84	high_impact	3,58	damaging	0,57	neutral	0,54	deleterious	3,76	23,3	0,14	0,55	disease	0,66	disease	0,91	neutral	0,43	disease	0,74	5	deleterious	1	neutral	0,16	deleterious	5	deleterious	0,7	low_impact	-1,08	low_impact	-1,48	high_impact	2,21	0,71	0,9	10,14	12,66	N	0,38	N	0,86	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14631	14631	C	A	MI.24100	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	43	15	G	W	Ggg/Tgg	1,1	0	0	probably_damaging	1	neutral	0,18	neutral	2,13	deleterious	-7,97	deleterious	-6,79	medium_impact	2,8	neutral	0,69	neutral	0,35	deleterious	4,71	24,6	0,2	0,45	disease	0,92	disease	0,84	disease	0,64	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-3,55	medium_impact	-0,16	medium_impact	1,21	0,72	0,85	11,5	26,27	N	0,29	N	0,99	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14631	14631	C	G	MI.24101	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	43	15	G	R	Ggg/Cgg	1,1	0	0	probably_damaging	0,99	neutral	0,35	neutral	2,14	deleterious	-5,04	deleterious	-6,44	high_impact	3,84	damaging	0,51	damaging	0,14	deleterious	4,01	23,6	0,19	0,45	disease	0,66	disease	0,87	disease	0,79	disease	0,83	7	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,86	low_impact	-2,63	medium_impact	0,06	high_impact	2,08	0,82	0,85	11,5	26,27	N	0,46	N	0,97	NA	NA	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14632	14632	C	G	MI.24102	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	42	14	M	I	atG/atC	0,41	0	0	benign	0,13	neutral	0,51	neutral	2,33	neutral	-1,79	neutral	0,57	neutral_impact	0,7	neutral	0,92	neutral	0,99	neutral	-0,57	0,15	0,53	0,6	neutral	0,13	neutral	0,29	neutral	0,38	neutral	0,42	2	neutral	0,4	deleterious	0,69	neutral	-6	neutral	0,16	medium_impact	-0,04	medium_impact	0,22	medium_impact	-0,55	0,69	0,85	13,72	12,42	N	0,39	N	0,74	NA	NA	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14632	14632	C	A	MI.24103	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	42	14	M	I	atG/atT	0,41	0	0	benign	0,13	neutral	0,51	neutral	2,33	neutral	-1,79	neutral	0,57	neutral_impact	0,7	neutral	0,92	neutral	0,99	neutral	-0,17	1,27	0,53	0,6	neutral	0,13	neutral	0,29	neutral	0,38	neutral	0,42	2	neutral	0,4	deleterious	0,69	neutral	-6	neutral	0,16	medium_impact	-0,04	medium_impact	0,22	medium_impact	-0,55	0,69	0,85	13,72	12,42	N	0,39	N	0,74	NA	NA	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14633	14633	A	G	MI.24104	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	41	14	M	T	aTg/aCg	-9,68	0	0	benign	0,02	neutral	0,25	neutral	2,31	deleterious	-3,75	neutral	-2,29	low_impact	1,5	neutral	0,85	neutral	0,84	deleterious	-0,01	2,48	0,44	0,55	neutral	0,16	neutral	0,33	disease	0,64	neutral	0,48	0	neutral	0,74	deleterious	0,62	neutral	-6	neutral	0,12	medium_impact	0,75	medium_impact	-0,06	medium_impact	0,12	0,56	0,8	13,72	12,42	N	0,4	N	0,49	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14633	14633	A	T	MI.24105	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	41	14	M	K	aTg/aAg	-9,68	0	0	possibly_damaging	0,45	neutral	0,1	neutral	2,25	deleterious	-4,95	deleterious	-3,87	medium_impact	2,54	neutral	0,81	neutral	0,42	deleterious	3,31	22,9	0,29	0,45	neutral	0,34	disease	0,66	disease	0,7	disease	0,76	5	neutral	0,89	neutral	0,33	NA	0	deleterious	0,5	medium_impact	-0,72	medium_impact	-0,32	medium_impact	0,99	0,68	0,85	13,72	12,42	N	0,37	N	0,91	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14634	14634	T	A	MI.24106	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	40	14	M	L	Atg/Ttg	2,25	0,33	0,01	benign	0,06	neutral	1	neutral	2,39	neutral	-0,15	neutral	0,04	neutral_impact	0,3	neutral	0,9	neutral	0,99	neutral	-1,12	0,01	0,47	0,55	neutral	0,09	neutral	0,16	neutral	0,35	neutral	0,23	5	neutral	0,06	deleterious	0,97	neutral	-6	neutral	0,15	medium_impact	0,3	high_impact	1,87	medium_impact	-0,89	0,61	0,8	13,72	12,42	N	0,34	N	0,64	NA	NA	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14634	14634	T	C	MI.24107	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	40	14	M	V	Atg/Gtg	2,25	0,33	0,01	benign	0,01	neutral	0,68	neutral	2,34	neutral	-1,86	neutral	0,48	neutral_impact	-0,31	neutral	0,93	neutral	0,98	neutral	-2,2	0	0,6	0,65	neutral	0,09	neutral	0,21	neutral	0,37	neutral	0,33	3	neutral	0,31	deleterious	0,84	neutral	-6	neutral	0,08	medium_impact	1,03	medium_impact	0,39	low_impact	-1,4	0,62	0,8	13,72	12,42	N	0,4	N	0,4	NA	NA	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14634	14634	T	G	MI.24108	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	40	14	M	L	Atg/Ctg	2,25	0,33	0,01	benign	0,06	neutral	1	neutral	2,39	neutral	-0,15	neutral	0,04	neutral_impact	0,3	neutral	0,9	neutral	0,99	neutral	-1,2	0,01	0,47	0,55	neutral	0,09	neutral	0,16	neutral	0,35	neutral	0,23	5	neutral	0,06	deleterious	0,97	neutral	-6	neutral	0,15	medium_impact	0,3	high_impact	1,87	medium_impact	-0,89	0,61	0,8	13,72	12,42	N	0,34	N	0,64	NA	NA	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14636	14636	A	T	MI.24109	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	38	13	V	E	gTa/gAa	-20	0	0	probably_damaging	0,98	neutral	0,09	neutral	1,89	deleterious	-5,12	deleterious	-5,44	high_impact	3,77	neutral	0,83	neutral	0,36	deleterious	4,03	23,6	0,13	0,4	disease	0,74	disease	0,88	disease	0,82	disease	0,85	7	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-2,35	medium_impact	-0,35	high_impact	2,02	0,57	0,8	15,49	16,77	N	0,37	N	0,92	NA	NA	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6150	6150	G	C	MI.2411	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	247	83	V	L	Gtt/Ctt	-2,88	0	0	benign	0,02	neutral	0,45	neutral	2,7	neutral	-0,57	neutral	-1,4	low_impact	1,08	damaging	0,56	neutral	0,55	deleterious	2,23	17,73	0,36	0,55	neutral	0,21	disease	0,67	neutral	0,2	neutral	0,45	1	neutral	0,53	deleterious	0,72	neutral	-6	neutral	0,19	medium_impact	0,83	medium_impact	0,14	medium_impact	-0,1	0,75	0,9	10,14	12,66	N	0,44	N	0,55	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14636	14636	A	G	MI.24110	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	38	13	V	A	gTa/gCa	-20	0	0	possibly_damaging	0,82	neutral	0,32	neutral	1,96	deleterious	-3,5	deleterious	-3,34	medium_impact	2,87	neutral	0,91	neutral	0,81	deleterious	0,51	7,52	0,35	0,5	neutral	0,43	disease	0,62	disease	0,7	disease	0,55	1	neutral	0,84	neutral	0,25	NA	0	deleterious	0,68	low_impact	-1,4	medium_impact	0,03	medium_impact	1,26	0,45	0,8	15,49	16,77	N	0,42	N	0,73	NA	NA	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14636	14636	A	C	MI.24111	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	38	13	V	G	gTa/gGa	-20	0	0	probably_damaging	0,98	neutral	0,26	neutral	1,9	deleterious	-5,18	deleterious	-6,29	high_impact	3,77	neutral	0,84	neutral	0,48	deleterious	3,05	22,4	0,18	0,45	disease	0,75	disease	0,82	disease	0,74	disease	0,78	6	deleterious	0,98	neutral	0,14	deleterious	2	deleterious	0,79	low_impact	-2,35	medium_impact	-0,05	high_impact	2,02	0,67	0,85	15,49	16,77	N	0,35	N	0,91	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14637	14637	C	G	MI.24112	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	37	13	V	L	Gta/Cta	4,54	0,32	0	possibly_damaging	0,62	neutral	0,62	neutral	2,07	neutral	-2,87	neutral	-2,34	medium_impact	2,05	neutral	0,9	neutral	0,81	deleterious	0,85	9,76	0,39	0,5	neutral	0,15	disease	0,59	disease	0,52	neutral	0,45	1	neutral	0,56	deleterious	0,5	NA	0	deleterious	0,51	medium_impact	-0,99	medium_impact	0,32	medium_impact	0,58	0,74	0,85	15,49	16,77	N	0,38	N	0,38	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14637	14637	C	T	MI.24113	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	37	13	V	M	Gta/Ata	4,54	0,32	0	probably_damaging	0,98	neutral	0,33	neutral	1,94	deleterious	-4,5	neutral	-2,38	medium_impact	2,48	neutral	0,89	neutral	0,66	deleterious	3,65	23,2	0,42	0,55	neutral	0,33	disease	0,62	disease	0,56	neutral	0,48	1	deleterious	0,98	neutral	0,18	deleterious	1	deleterious	0,69	low_impact	-2,35	medium_impact	0,04	medium_impact	0,94	0,71	0,85	15,49	16,77	N	0,41	N	0,65	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14637	14637	C	A	MI.24114	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	37	13	V	L	Gta/Tta	4,54	0,32	0	possibly_damaging	0,62	neutral	0,62	neutral	2,07	neutral	-2,87	neutral	-2,34	medium_impact	2,05	neutral	0,9	neutral	0,81	neutral	1,08	11,11	0,39	0,5	neutral	0,15	disease	0,59	disease	0,52	neutral	0,45	1	neutral	0,56	deleterious	0,5	NA	0	deleterious	0,51	medium_impact	-0,99	medium_impact	0,32	medium_impact	0,58	0,74	0,85	15,49	16,77	N	0,34	N	0,38	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14638	14638	T	A	MI.24115	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	36	12	L	F	ttA/ttT	0,18	0,07	0	possibly_damaging	0,45	neutral	0,69	neutral	2,08	neutral	-1,59	neutral	3,31	low_impact	1,18	neutral	0,83	neutral	0,97	neutral	1,04	10,88	0,39	0,5	neutral	0,15	neutral	0,22	neutral	0,33	neutral	0,38	2	neutral	0,36	deleterious	0,62	neutral	-3	neutral	0,41	medium_impact	-0,72	medium_impact	0,4	medium_impact	-0,15	0,68	0,85	50	8,94	N	0,29	N	0,18	NA	NA	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14638	14638	T	G	MI.24116	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	36	12	L	F	ttA/ttC	0,18	0,07	0	possibly_damaging	0,45	neutral	0,69	neutral	2,08	neutral	-1,59	neutral	3,31	low_impact	1,18	neutral	0,83	neutral	0,97	deleterious	0,8	9,46	0,39	0,5	neutral	0,15	neutral	0,22	neutral	0,33	neutral	0,38	2	neutral	0,36	deleterious	0,62	neutral	-3	neutral	0,41	medium_impact	-0,72	medium_impact	0,4	medium_impact	-0,15	0,68	0,85	50	8,94	N	0,3	N	0,18	NA	NA	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14639	14639	A	C	MI.24117	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	35	12	L	W	tTa/tGa	-1,65	0	0	probably_damaging	1	neutral	0,06	neutral	1,87	deleterious	-6,45	neutral	-0,75	medium_impact	3,02	neutral	0,75	neutral	0,3	deleterious	3,21	22,7	0,14	0,4	disease	0,84	disease	0,86	disease	0,62	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,84	low_impact	-3,55	medium_impact	-0,46	medium_impact	1,39	0,59	0,8	50	8,94	N	0,32	N	0,72	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14639	14639	A	G	MI.24118	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	35	12	L	S	tTa/tCa	-1,65	0	0	probably_damaging	0,99	neutral	0,38	neutral	1,91	deleterious	-4,84	deleterious	-2,95	high_impact	3,57	neutral	0,74	damaging	0,22	deleterious	3,66	23,2	0,2	0,45	disease	0,72	disease	0,84	disease	0,66	disease	0,77	5	deleterious	0,99	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-2,63	medium_impact	0,09	medium_impact	1,85	0,63	0,8	50	8,94	N	0,31	N	0,82	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14640	14640	A	T	MI.24119	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	34	12	L	M	Tta/Ata	4,54	0,26	0	probably_damaging	0,99	neutral	0,4	neutral	1,95	neutral	-2,93	neutral	-0,49	medium_impact	2,07	neutral	0,77	neutral	0,45	deleterious	3,05	22,4	0,35	0,5	neutral	0,27	disease	0,57	neutral	0,42	neutral	0,48	0	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,69	low_impact	-2,63	medium_impact	0,11	medium_impact	0,59	0,71	0,85	50	8,94	N	0,39	N	0,52	NA	NA	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6151	6151	T	G	MI.2412	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	248	83	V	G	gTt/gGt	1,05	0,8	0	possibly_damaging	0,84	deleterious	0	neutral	2,51	deleterious	-3,97	deleterious	-4,65	high_impact	4,56	neutral	0,65	neutral	0,63	deleterious	3,8	23,4	0,13	0,55	disease	0,81	disease	0,81	disease	0,59	disease	0,72	4	deleterious	1	neutral	0,08	deleterious	5	deleterious	0,77	low_impact	-1,43	low_impact	-1,48	high_impact	3,11	0,56	0,9	10,14	12,66	N	0,45	N	0,71	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14640	14640	A	C	MI.24120	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	34	12	L	V	Tta/Gta	4,54	0,26	0	probably_damaging	0,94	neutral	0,3	neutral	2,01	neutral	-2,46	neutral	-1,34	medium_impact	2,29	neutral	0,8	neutral	0,54	deleterious	2,9	21,8	0,35	0,5	neutral	0,37	disease	0,7	neutral	0,47	disease	0,56	1	neutral	0,95	neutral	0,18	deleterious	1	deleterious	0,72	low_impact	-1,89	medium_impact	0	medium_impact	0,78	0,68	0,85	50	8,94	N	0,38	N	0,51	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14642	14642	C	A	MI.24121	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	32	11	G	V	gGt/gTt	-5,78	0	0	benign	0	neutral	0,62	neutral	2,27	neutral	-1,12	neutral	5,22	low_impact	0,97	neutral	0,88	neutral	0,95	deleterious	0,54	7,7	0,32	0,5	neutral	0,09	disease	0,81	neutral	0,48	disease	0,59	2	neutral	0,37	deleterious	0,81	neutral	-6	neutral	0,13	medium_impact	1,95	medium_impact	0,32	medium_impact	-0,33	0,78	0,85	23,45	19,76	N	0,26	N	0,04	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14642	14642	C	G	MI.24122	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	32	11	G	A	gGt/gCt	-5,78	0	0	benign	0,02	neutral	0,52	neutral	2,24	neutral	-1,72	neutral	2,62	low_impact	0,98	neutral	0,86	neutral	0,93	deleterious	-0,06	2,04	0,5	0,6	neutral	0,13	disease	0,62	disease	0,51	neutral	0,44	1	neutral	0,45	deleterious	0,75	neutral	-6	neutral	0,13	medium_impact	0,75	medium_impact	0,23	medium_impact	-0,32	0,86	0,9	23,45	19,76	N	0,25	N	0,11	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14642	14642	C	T	MI.24123	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	32	11	G	D	gGt/gAt	-5,78	0	0	benign	0,16	neutral	0,18	neutral	2,13	deleterious	-4,01	neutral	0,15	medium_impact	2,52	neutral	0,78	neutral	0,41	deleterious	2,06	16,62	0,16	0,45	neutral	0,45	disease	0,89	disease	0,69	disease	0,79	6	neutral	0,79	deleterious	0,51	neutral	-3	neutral	0,36	medium_impact	-0,14	medium_impact	-0,16	medium_impact	0,97	0,68	0,85	23,45	19,76	N	0,34	N	0,32	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14643	14643	C	T	MI.24124	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	31	11	G	S	Ggt/Agt	1,1	0	0	benign	0,06	neutral	0,54	neutral	2,2	neutral	-2,36	neutral	1,64	low_impact	1,71	neutral	0,83	neutral	0,89	deleterious	2,32	18,32	0,37	0,5	neutral	0,21	disease	0,65	neutral	0,43	neutral	0,47	1	neutral	0,4	deleterious	0,74	neutral	-6	neutral	0,15	medium_impact	0,3	medium_impact	0,25	medium_impact	0,29	0,9	0,95	23,45	19,76	N	0,34	N	0,03	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14643	14643	C	G	MI.24125	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	31	11	G	R	Ggt/Cgt	1,1	0	0	benign	0,16	neutral	0,31	neutral	2,15	deleterious	-3,18	neutral	0,97	medium_impact	2,52	neutral	0,79	neutral	0,42	deleterious	2,18	17,4	0,2	0,45	neutral	0,33	disease	0,9	disease	0,72	disease	0,8	6	neutral	0,64	deleterious	0,58	neutral	-3	neutral	0,38	medium_impact	-0,14	medium_impact	0,01	medium_impact	0,97	0,81	0,85	23,45	19,76	N	0,34	N	0,23	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14643	14643	C	A	MI.24126	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	31	11	G	C	Ggt/Tgt	1,1	0	0	possibly_damaging	0,59	neutral	0,26	neutral	2,2	deleterious	-3,87	neutral	2,26	neutral_impact	0,67	neutral	0,79	neutral	0,78	deleterious	4,19	23,8	0,25	0,45	neutral	0,23	disease	0,68	neutral	0,47	neutral	0,49	0	neutral	0,75	neutral	0,34	neutral	-3	deleterious	0,51	medium_impact	-0,94	medium_impact	-0,05	medium_impact	-0,58	0,8	0,85	23,45	19,76	N	0,34	N	0,26	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14645	14645	A	T	MI.24127	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	29	10	V	E	gTg/gAg	-7,38	0	0	probably_damaging	0,97	neutral	0,13	neutral	2,1	deleterious	-4,14	deleterious	-4,81	medium_impact	3,37	neutral	0,86	neutral	0,51	deleterious	4,14	23,8	0,22	0,45	neutral	0,47	disease	0,84	disease	0,76	disease	0,8	6	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,76	low_impact	-2,18	medium_impact	-0,25	medium_impact	1,68	0,75	0,85	27,43	16,7	N	0,42	N	0,9	NA	NA	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14645	14645	A	G	MI.24128	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	29	10	V	A	gTg/gCg	-7,38	0	0	possibly_damaging	0,77	neutral	0,27	neutral	2,17	neutral	-2,56	deleterious	-3,1	medium_impact	2,56	neutral	0,84	neutral	0,75	neutral	1,56	13,63	0,43	0,55	neutral	0,18	disease	0,57	disease	0,56	disease	0,62	2	neutral	0,83	neutral	0,25	NA	0	deleterious	0,58	low_impact	-1,28	medium_impact	-0,03	medium_impact	1	0,68	0,85	27,43	16,7	N	0,35	N	0,47	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14645	14645	A	C	MI.24129	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	29	10	V	G	gTg/gGg	-7,38	0	0	probably_damaging	0,97	neutral	0,32	neutral	2,11	neutral	-1,82	deleterious	-5,76	medium_impact	2,33	neutral	0,86	neutral	0,7	deleterious	1,94	15,81	0,31	0,45	neutral	0,47	disease	0,73	disease	0,59	disease	0,7	4	neutral	0,97	neutral	0,18	deleterious	1	deleterious	0,71	low_impact	-2,18	medium_impact	0,03	medium_impact	0,81	0,72	0,85	27,43	16,7	N	0,31	N	0,85	NA	NA	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6151	6151	T	C	MI.2413	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	248	83	V	A	gTt/gCt	1,05	0,8	0	benign	0,42	deleterious	0	neutral	2,59	neutral	-1,93	deleterious	-2,6	high_impact	3,52	neutral	0,66	neutral	0,67	deleterious	3,51	23,1	0,33	0,55	disease	0,58	disease	0,77	disease	0,54	disease	0,69	4	deleterious	1	neutral	0,29	deleterious	2	neutral	0,42	medium_impact	-0,62	low_impact	-1,48	high_impact	2,15	0,55	0,9	10,14	12,66	N	0,37	N	0,47	polymorphism	0,78	0,14	rs1041870	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14646	14646	C	A	MI.24130	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	28	10	V	L	Gtg/Ttg	0,64	0	0	benign	0,39	neutral	1	neutral	2,34	neutral	-1,46	neutral	-1,74	low_impact	1,48	neutral	0,89	neutral	0,91	deleterious	0,73	9,04	0,47	0,55	neutral	0,12	disease	0,5	neutral	0,32	neutral	0,43	1	neutral	0,39	deleterious	0,81	neutral	-6	neutral	0,41	medium_impact	-0,62	high_impact	1,87	medium_impact	0,1	0,88	0,9	27,43	16,7	N	0,28	N	0,36	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14646	14646	C	T	MI.24131	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	28	10	V	M	Gtg/Atg	0,64	0	0	possibly_damaging	0,54	neutral	0,36	neutral	2,16	neutral	-2,4	neutral	-1,92	medium_impact	2,01	neutral	0,88	neutral	0,87	deleterious	0,82	9,59	0,51	0,6	neutral	0,23	neutral	0,43	neutral	0,36	neutral	0,45	1	neutral	0,64	neutral	0,41	NA	0	deleterious	0,5	medium_impact	-0,86	medium_impact	0,07	medium_impact	0,54	0,84	0,9	27,43	16,7	N	0,42	N	0,6	NA	NA	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14646	14646	C	G	MI.24132	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	28	10	V	L	Gtg/Ctg	0,64	0	0	benign	0,39	neutral	1	neutral	2,34	neutral	-1,46	neutral	-1,74	low_impact	1,48	neutral	0,89	neutral	0,91	deleterious	0,4	6,61	0,47	0,55	neutral	0,12	disease	0,5	neutral	0,32	neutral	0,43	1	neutral	0,39	deleterious	0,81	neutral	-6	neutral	0,41	medium_impact	-0,62	high_impact	1,87	medium_impact	0,1	0,88	0,9	27,43	16,7	N	0,28	N	0,36	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14648	14648	C	G	MI.24133	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	26	9	S	T	aGt/aCt	-2,34	0	0	probably_damaging	1	neutral	0,25	neutral	2,27	neutral	-2,19	deleterious	-2,99	medium_impact	2,75	neutral	0,84	damaging	0,22	deleterious	3,45	23	0,29	0,45	neutral	0,29	neutral	0,47	disease	0,55	disease	0,53	1	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,72	low_impact	-3,55	medium_impact	-0,06	medium_impact	1,16	0,75	0,85	49,56	8,77	N	0,32	N	0,68	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14648	14648	C	T	MI.24134	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	26	9	S	N	aGt/aAt	-2,34	0	0	probably_damaging	1	neutral	0,11	neutral	2,21	deleterious	-3,01	deleterious	-2,99	high_impact	3,56	neutral	0,76	damaging	0,15	deleterious	3,57	23,1	0,49	0,55	neutral	0,39	disease	0,63	disease	0,58	disease	0,72	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,75	low_impact	-3,55	medium_impact	-0,3	medium_impact	1,84	0,67	0,85	49,56	8,77	N	0,37	N	0,82	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14648	14648	C	A	MI.24135	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	26	9	S	I	aGt/aTt	-2,34	0	0	probably_damaging	1	neutral	0,41	neutral	2,29	neutral	-2,21	deleterious	-5,87	medium_impact	2,66	neutral	0,83	damaging	0,17	deleterious	4,23	23,9	0,37	0,5	neutral	0,3	disease	0,85	neutral	0,47	disease	0,78	6	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,76	low_impact	-3,55	medium_impact	0,12	medium_impact	1,09	0,89	0,9	49,56	8,77	N	0,25	N	0,98	NA	NA	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14649	14649	T	C	MI.24136	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	25	9	S	G	Agt/Ggt	2,48	0,02	0	probably_damaging	1	neutral	0,28	neutral	2,28	neutral	-1,1	deleterious	-3,96	medium_impact	2,12	neutral	0,79	neutral	0,38	deleterious	3,24	22,8	0,34	0,5	neutral	0,28	neutral	0,34	neutral	0,46	neutral	0,45	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,69	low_impact	-3,55	medium_impact	-0,02	medium_impact	0,64	0,77	0,85	49,56	8,77	N	0,4	N	0,83	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14649	14649	T	A	MI.24137	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	25	9	S	C	Agt/Tgt	2,48	0,02	0	probably_damaging	1	neutral	0,12	neutral	2,21	deleterious	-4,32	deleterious	-4,92	medium_impact	3,01	neutral	0,78	damaging	0,27	deleterious	3,61	23,2	0,37	0,5	disease	0,6	disease	0,77	disease	0,54	disease	0,75	5	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,77	low_impact	-3,55	medium_impact	-0,27	medium_impact	1,38	0,79	0,85	49,56	8,77	N	0,35	N	0,98	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14649	14649	T	G	MI.24138	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	25	9	S	R	Agt/Cgt	2,48	0,02	0	probably_damaging	1	neutral	0,1	neutral	2,22	neutral	-2,91	deleterious	-4,91	high_impact	3,56	neutral	0,82	damaging	0,14	deleterious	3,87	23,5	0,23	0,45	neutral	0,37	disease	0,87	disease	0,69	disease	0,8	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,81	low_impact	-3,55	medium_impact	-0,32	medium_impact	1,84	0,91	0,95	49,56	8,77	N	0,36	N	1	NA	NA	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14650	14650	C	G	MI.24139	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	24	8	L	F	ttG/ttC	0,41	0,01	0	benign	0,32	neutral	0,74	neutral	2,07	neutral	-2,55	deleterious	-3,42	low_impact	1,7	neutral	0,9	neutral	0,94	deleterious	0,54	7,71	0,4	0,5	disease	0,57	neutral	0,22	neutral	0,35	disease	0,53	1	neutral	0,22	deleterious	0,71	neutral	-6	neutral	0,37	medium_impact	-0,5	medium_impact	0,46	medium_impact	0,28	0,7	0,85	21,24	17,86	N	0,41	N	0,85	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6151	6151	T	A	MI.2414	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	248	83	V	D	gTt/gAt	1,05	0,8	0	possibly_damaging	0,85	deleterious	0	neutral	2,48	deleterious	-5,08	deleterious	-4,46	high_impact	4,56	damaging	0,57	neutral	0,49	deleterious	4,5	24,3	0,09	0,55	disease	0,89	disease	0,91	disease	0,68	disease	0,81	6	deleterious	1	neutral	0,08	deleterious	5	deleterious	0,78	low_impact	-1,47	low_impact	-1,48	high_impact	3,11	0,58	0,9	10,14	12,66	N	0,45	N	0,83	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14650	14650	C	A	MI.24140	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	24	8	L	F	ttG/ttT	0,41	0,01	0	benign	0,32	neutral	0,74	neutral	2,07	neutral	-2,55	deleterious	-3,42	low_impact	1,7	neutral	0,9	neutral	0,94	neutral	0,92	10,2	0,4	0,5	disease	0,57	neutral	0,22	neutral	0,35	disease	0,53	1	neutral	0,22	deleterious	0,71	neutral	-6	neutral	0,37	medium_impact	-0,5	medium_impact	0,46	medium_impact	0,28	0,7	0,85	21,24	17,86	N	0,38	N	0,85	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14651	14651	A	G	MI.24141	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	23	8	L	S	tTg/tCg	-4,4	0	0	probably_damaging	0,98	neutral	0,48	neutral	1,99	deleterious	-4,37	deleterious	-5,25	medium_impact	2,54	neutral	0,81	neutral	0,82	deleterious	3,59	23,2	0,26	0,45	neutral	0,32	disease	0,69	disease	0,6	disease	0,56	1	deleterious	0,98	neutral	0,25	deleterious	1	deleterious	0,74	low_impact	-2,35	medium_impact	0,19	medium_impact	0,99	0,75	0,85	21,24	17,86	N	0,27	N	0,9	NA	NA	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14651	14651	A	C	MI.24142	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	23	8	L	W	tTg/tGg	-4,4	0	0	probably_damaging	0,99	neutral	0,1	neutral	1,93	deleterious	-6,42	deleterious	-5,28	medium_impact	2,99	neutral	0,76	neutral	0,64	deleterious	3,21	22,7	0,14	0,4	disease	0,86	disease	0,78	disease	0,62	disease	0,76	5	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,82	low_impact	-2,63	medium_impact	-0,32	medium_impact	1,37	0,61	0,8	21,24	17,86	N	0,33	N	0,91	NA	NA	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14652	14652	A	C	MI.24143	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	22	8	L	V	Ttg/Gtg	5,46	0,55	0	possibly_damaging	0,87	neutral	0,31	neutral	2,07	neutral	-2,1	deleterious	-2,64	medium_impact	2,64	neutral	0,81	neutral	0,79	deleterious	2,64	20,4	0,35	0,5	neutral	0,4	disease	0,6	neutral	0,44	neutral	0,49	0	neutral	0,89	neutral	0,22	NA	0	deleterious	0,7	low_impact	-1,55	medium_impact	0,01	medium_impact	1,07	0,68	0,85	21,24	17,86	N	0,44	N	0,69	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14652	14652	A	T	MI.24144	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	22	8	L	M	Ttg/Atg	5,46	0,55	0	probably_damaging	0,98	neutral	0,35	neutral	1,99	deleterious	-3,45	neutral	-1,21	medium_impact	2,17	neutral	0,84	neutral	0,97	deleterious	1,95	15,88	0,34	0,5	disease	0,58	neutral	0,4	neutral	0,37	disease	0,61	2	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,72	low_impact	-2,35	medium_impact	0,06	medium_impact	0,68	0,67	0,85	21,24	17,86	N	0,51	P	0,64	NA	NA	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14654	14654	A	C	MI.24145	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	20	7	L	R	cTg/cGg	-5,32	0	0	possibly_damaging	0,79	deleterious	0,03	neutral	1,92	deleterious	-4,39	deleterious	-4,74	medium_impact	3,45	neutral	0,73	neutral	0,44	deleterious	3,37	22,9	0,17	0,45	disease	0,67	disease	0,88	disease	0,76	disease	0,84	7	neutral	0,98	neutral	0,12	deleterious	4	deleterious	0,77	low_impact	-1,32	medium_impact	-0,63	medium_impact	1,75	0,74	0,85	9,29	10,06	N	0,35	N	0,64	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14654	14654	A	T	MI.24146	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	20	7	L	Q	cTg/cAg	-5,32	0	0	possibly_damaging	0,88	deleterious	0,03	neutral	1,91	deleterious	-4,43	deleterious	-4,55	medium_impact	3,45	neutral	0,79	neutral	0,51	deleterious	3,38	23	0,21	0,45	disease	0,67	disease	0,69	disease	0,65	disease	0,73	5	deleterious	0,99	neutral	0,08	deleterious	4	deleterious	0,71	low_impact	-1,59	medium_impact	-0,63	medium_impact	1,75	0,8	0,85	9,29	10,06	N	0,38	N	0,68	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14654	14654	A	G	MI.24147	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	20	7	L	P	cTg/cCg	-5,32	0	0	possibly_damaging	0,79	neutral	0,05	neutral	1,91	deleterious	-4,95	deleterious	-5,08	medium_impact	3,1	neutral	0,74	neutral	0,4	deleterious	3,52	23,1	0,16	0,45	disease	0,72	disease	0,86	disease	0,65	disease	0,77	5	neutral	0,97	neutral	0,13	NA	0	deleterious	0,76	low_impact	-1,32	medium_impact	-0,5	medium_impact	1,46	0,72	0,85	9,29	10,06	N	0,35	N	0,82	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14655	14655	G	C	MI.24148	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	19	7	L	V	Ctg/Gtg	1,1	0	0	benign	0,02	neutral	0,32	neutral	2,05	neutral	-0,8	neutral	-0,28	low_impact	1,4	neutral	0,9	neutral	0,95	neutral	-0,28	0,72	0,42	0,5	neutral	0,14	neutral	0,4	neutral	0,4	neutral	0,45	1	neutral	0,67	deleterious	0,65	neutral	-6	neutral	0,1	medium_impact	0,75	medium_impact	0,03	medium_impact	0,03	0,76	0,85	9,29	10,06	N	0,47	N	0,2	NA	NA	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14655	14655	G	T	MI.24149	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	19	7	L	M	Ctg/Atg	1,1	0	0	possibly_damaging	0,84	neutral	0,3	neutral	1,97	neutral	-2,16	neutral	-0,76	low_impact	1,93	neutral	0,88	neutral	0,92	deleterious	0,19	4,53	0,36	0,5	neutral	0,36	neutral	0,31	neutral	0,33	neutral	0,46	1	neutral	0,87	neutral	0,23	neutral	-3	deleterious	0,59	low_impact	-1,46	medium_impact	0	medium_impact	0,48	0,62	0,8	9,29	10,06	N	0,49	N	0,32	NA	NA	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6153	6153	C	T	MI.2415	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	250	84	P	S	Ccc/Tcc	-20	0	0	possibly_damaging	0,8	deleterious	0	neutral	1,73	deleterious	-3,16	deleterious	-5,48	high_impact	4,89	neutral	0,68	damaging	0,04	deleterious	3,82	23,4	0,27	0,55	disease	0,68	disease	0,87	disease	0,64	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	5	deleterious	0,73	low_impact	-1,32	low_impact	-1,48	high_impact	3,42	0,37	0,9	2,92	6,76	N	0,56	P	0,85	polymorphism	0,94	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14656	14656	A	T	MI.24150	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	18	6	F	L	ttT/ttA	-2,11	0	0	benign	0,04	neutral	0,79	neutral	2,29	neutral	-1,93	deleterious	-4,9	low_impact	1,5	neutral	0,93	neutral	0,77	deleterious	0,7	8,8	0,26	0,45	neutral	0,18	disease	0,54	neutral	0,47	neutral	0,46	1	neutral	0,14	deleterious	0,88	neutral	-6	neutral	0,15	medium_impact	0,47	medium_impact	0,53	medium_impact	0,12	0,5	0,8	39,82	8,43	N	0,32	N	0,84	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14656	14656	A	C	MI.24151	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	18	6	F	L	ttT/ttG	-2,11	0	0	benign	0,04	neutral	0,79	neutral	2,29	neutral	-1,93	deleterious	-4,9	low_impact	1,5	neutral	0,93	neutral	0,77	deleterious	0,62	8,29	0,26	0,45	neutral	0,18	disease	0,54	neutral	0,47	neutral	0,46	1	neutral	0,14	deleterious	0,88	neutral	-6	neutral	0,15	medium_impact	0,47	medium_impact	0,53	medium_impact	0,12	0,5	0,8	39,82	8,43	N	0,32	N	0,84	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14657	14657	A	G	MI.24152	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	17	6	F	S	tTt/tCt	-0,04	0	0	probably_damaging	0,91	neutral	0,45	neutral	2,2	neutral	-0,93	deleterious	-6,25	medium_impact	2,25	neutral	0,85	neutral	0,77	deleterious	4,28	24	0,4	0,5	neutral	0,17	disease	0,65	disease	0,54	neutral	0,47	1	neutral	0,9	neutral	0,27	deleterious	1	deleterious	0,68	low_impact	-1,72	medium_impact	0,16	medium_impact	0,75	0,69	0,85	39,82	8,43	N	0,28	N	0,93	NA	NA	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14657	14657	A	C	MI.24153	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	17	6	F	C	tTt/tGt	-0,04	0	0	probably_damaging	0,97	neutral	0,13	neutral	2,13	deleterious	-4,48	deleterious	-6,73	medium_impact	2,46	neutral	0,83	neutral	0,69	deleterious	3,77	23,4	0,28	0,45	disease	0,56	disease	0,78	neutral	0,5	disease	0,6	2	deleterious	0,98	neutral	0,08	deleterious	1	deleterious	0,73	low_impact	-2,18	medium_impact	-0,25	medium_impact	0,92	0,45	0,8	39,82	8,43	N	0,37	N	0,96	NA	NA	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14657	14657	A	T	MI.24154	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	17	6	F	Y	tTt/tAt	-0,04	0	0	possibly_damaging	0,78	neutral	0,39	neutral	2,17	deleterious	-3,24	neutral	-1,76	low_impact	1,69	neutral	0,85	neutral	0,92	deleterious	2,23	17,73	0,25	0,45	neutral	0,41	disease	0,58	neutral	0,47	neutral	0,49	0	neutral	0,79	neutral	0,31	neutral	-3	deleterious	0,65	low_impact	-1,3	medium_impact	0,1	medium_impact	0,28	0,58	0,8	39,82	8,43	N	0,37	N	0,49	NA	NA	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14658	14658	A	C	MI.24155	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	16	6	F	V	Ttt/Gtt	-0,04	0	0	possibly_damaging	0,57	neutral	0,43	neutral	2,25	neutral	-2,04	deleterious	-5,73	medium_impact	2,37	neutral	0,81	neutral	0,73	deleterious	2,11	16,9	0,29	0,45	neutral	0,15	disease	0,78	disease	0,52	disease	0,58	2	neutral	0,6	neutral	0,43	NA	0	deleterious	0,53	medium_impact	-0,91	medium_impact	0,14	medium_impact	0,85	0,61	0,8	39,82	8,43	N	0,31	N	0,9	NA	NA	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14658	14658	A	G	MI.24156	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	16	6	F	L	Ttt/Ctt	-0,04	0	0	benign	0,04	neutral	0,79	neutral	2,29	neutral	-1,93	deleterious	-4,9	low_impact	1,5	neutral	0,93	neutral	0,77	neutral	0,94	10,33	0,26	0,45	neutral	0,18	disease	0,54	neutral	0,47	neutral	0,46	1	neutral	0,14	deleterious	0,88	neutral	-6	neutral	0,15	medium_impact	0,47	medium_impact	0,53	medium_impact	0,12	0,5	0,8	39,82	8,43	N	0,3	N	0,84	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14658	14658	A	T	MI.24157	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	16	6	F	I	Ttt/Att	-0,04	0	0	possibly_damaging	0,44	neutral	0,46	neutral	2,21	neutral	-2,46	deleterious	-4,97	medium_impact	2,37	neutral	0,82	neutral	0,7	deleterious	2,24	17,78	0,2	0,45	neutral	0,17	disease	0,74	neutral	0,5	disease	0,58	1	neutral	0,5	deleterious	0,51	NA	0	deleterious	0,5	medium_impact	-0,7	medium_impact	0,17	medium_impact	0,85	0,59	0,8	39,82	8,43	N	0,3	N	0,88	NA	NA	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14659	14659	C	A	MI.24158	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	15	5	L	F	ttG/ttT	1,1	0	0	probably_damaging	0,99	neutral	0,84	neutral	2,17	deleterious	-4,88	neutral	-1,87	low_impact	1,84	neutral	0,83	neutral	0,41	deleterious	4,04	23,7	0,42	0,55	neutral	0,44	neutral	0,27	neutral	0,4	neutral	0,45	1	deleterious	0,99	neutral	0,43	neutral	-2	deleterious	0,66	low_impact	-2,63	medium_impact	0,61	medium_impact	0,4	0,78	0,85	50,44	8,42	N	0,25	N	0,31	NA	NA	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14659	14659	C	G	MI.24159	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	15	5	L	F	ttG/ttC	1,1	0	0	probably_damaging	0,99	neutral	0,84	neutral	2,17	deleterious	-4,88	neutral	-1,87	low_impact	1,84	neutral	0,83	neutral	0,41	deleterious	3,58	23,2	0,42	0,55	neutral	0,44	neutral	0,27	neutral	0,4	neutral	0,45	1	deleterious	0,99	neutral	0,43	neutral	-2	deleterious	0,66	low_impact	-2,63	medium_impact	0,61	medium_impact	0,4	0,78	0,85	50,44	8,42	N	0,23	N	0,31	NA	NA	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6153	6153	C	A	MI.2416	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	250	84	P	T	Ccc/Acc	-20	0	0	possibly_damaging	0,63	deleterious	0	neutral	1,55	deleterious	-5,74	deleterious	-5,49	high_impact	5,24	neutral	0,69	damaging	0,04	deleterious	3,58	23,2	0,23	0,55	disease	0,72	disease	0,88	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,19	deleterious	5	deleterious	0,62	medium_impact	-0,97	low_impact	-1,48	high_impact	3,74	0,67	0,9	2,92	6,76	N	0,5	N	0,8	polymorphism	0,94	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14660	14660	A	C	MI.24160	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	14	5	L	W	tTg/tGg	-8,76	0	0	probably_damaging	1	neutral	0,09	neutral	2,11	deleterious	-8,03	deleterious	-3,49	medium_impact	2,58	neutral	0,79	damaging	0,21	deleterious	3,09	22,5	0,18	0,45	disease	0,81	neutral	0,47	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,75	low_impact	-3,55	medium_impact	-0,35	medium_impact	1,02	0,59	0,8	50,44	8,42	N	0,28	N	0,74	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14660	14660	A	G	MI.24161	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	14	5	L	S	tTg/tCg	-8,76	0	0	probably_damaging	0,92	neutral	0,22	neutral	2,18	deleterious	-6,33	deleterious	-2,78	low_impact	1,51	neutral	0,85	neutral	0,47	deleterious	3,41	23	0,29	0,45	disease	0,53	neutral	0,23	neutral	0,41	neutral	0,36	3	neutral	0,94	neutral	0,15	neutral	-2	deleterious	0,67	low_impact	-1,77	medium_impact	-0,1	medium_impact	0,13	0,82	0,85	50,44	8,42	N	0,39	N	0,62	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14661	14661	A	T	MI.24162	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	13	5	L	M	Ttg/Atg	1,56	0	0	probably_damaging	0,99	neutral	0,56	neutral	2,26	deleterious	-4,52	neutral	0,23	low_impact	1,19	neutral	0,88	neutral	0,89	neutral	1,8	14,97	0,36	0,5	neutral	0,28	neutral	0,05	neutral	0,26	neutral	0,21	6	deleterious	0,99	neutral	0,29	neutral	-2	deleterious	0,61	low_impact	-2,63	medium_impact	0,27	medium_impact	-0,14	0,77	0,85	50,44	8,42	N	0,39	N	0,15	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14661	14661	A	C	MI.24163	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	13	5	L	V	Ttg/Gtg	1,56	0	0	possibly_damaging	0,87	neutral	0,53	neutral	2,37	neutral	-2,22	neutral	1,27	neutral_impact	0,6	neutral	0,91	neutral	0,94	neutral	-1,59	0	0,45	0,55	neutral	0,11	neutral	0,06	neutral	0,29	neutral	0,17	7	neutral	0,85	neutral	0,33	neutral	-3	deleterious	0,56	low_impact	-1,55	medium_impact	0,24	medium_impact	-0,64	0,85	0,9	50,44	8,42	N	0,39	N	0,18	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14663	14663	G	C	MI.24164	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	11	4	A	G	gCt/gGt	-2,11	0	0	benign	0,21	neutral	0,2	neutral	2,24	deleterious	-3,84	deleterious	-2,7	low_impact	1,45	neutral	0,81	neutral	0,6	neutral	1,72	14,53	0,36	0,5	neutral	0,42	neutral	0,14	neutral	0,33	neutral	0,33	3	neutral	0,76	deleterious	0,5	neutral	-6	neutral	0,24	medium_impact	-0,27	medium_impact	-0,13	medium_impact	0,08	0,9	0,95	41,59	7,51	N	0,43	N	0,47	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14663	14663	G	T	MI.24165	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	11	4	A	D	gCt/gAt	-2,11	0	0	benign	0,4	neutral	0,05	neutral	2,22	deleterious	-4,41	neutral	-2,47	low_impact	1,8	neutral	0,85	neutral	0,55	deleterious	2,26	17,88	0,32	0,5	disease	0,53	neutral	0,41	disease	0,61	neutral	0,48	0	neutral	0,94	neutral	0,33	neutral	-6	deleterious	0,46	medium_impact	-0,64	medium_impact	-0,5	medium_impact	0,37	0,84	0,9	41,59	7,51	N	0,39	N	0,71	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14663	14663	G	A	MI.24166	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	11	4	A	V	gCt/gTt	-2,11	0	0	benign	0,01	neutral	0,37	neutral	2,4	neutral	-1,66	neutral	2,42	neutral_impact	-0,47	neutral	0,97	neutral	0,97	neutral	-0,19	1,13	0,41	0,5	neutral	0,16	neutral	0,08	neutral	0,22	neutral	0,27	5	neutral	0,62	deleterious	0,68	neutral	-6	neutral	0,06	medium_impact	1,03	medium_impact	0,08	low_impact	-1,53	0,96	1	41,59	7,51	N	0,42	N	0,12	NA	NA	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14664	14664	C	A	MI.24167	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	10	4	A	S	Gct/Tct	0,41	0	0	benign	0,14	neutral	0,24	neutral	2,28	neutral	-2,83	neutral	-1,14	low_impact	1,25	neutral	0,85	neutral	0,85	neutral	1,21	11,8	0,45	0,55	neutral	0,28	neutral	0,11	neutral	0,34	neutral	0,33	3	neutral	0,72	deleterious	0,55	neutral	-6	neutral	0,16	medium_impact	-0,07	medium_impact	-0,07	medium_impact	-0,09	0,96	1	41,59	7,51	N	0,51	P	0,51	NA	NA	0,03	rs386829223	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14664	14664	C	G	MI.24168	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	10	4	A	P	Gct/Cct	0,41	0	0	possibly_damaging	0,48	neutral	0,13	neutral	2,23	deleterious	-4,42	neutral	-2,07	low_impact	1,8	neutral	0,84	neutral	0,5	deleterious	2,32	18,32	0,2	0,45	neutral	0,49	neutral	0,46	neutral	0,36	neutral	0,43	1	neutral	0,85	neutral	0,33	neutral	-3	deleterious	0,54	medium_impact	-0,76	medium_impact	-0,25	medium_impact	0,37	0,94	0,95	41,59	7,51	N	0,43	N	0,71	NA	NA	0,04	rs386829223	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14664	14664	C	T	MI.24169	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	10	4	A	T	Gct/Act	0,41	0	0	benign	0,01	neutral	0,2	neutral	2,3	neutral	-2,63	neutral	0,04	neutral_impact	-0,08	neutral	0,94	neutral	0,91	neutral	1,05	10,94	0,57	0,65	neutral	0,24	neutral	0,07	neutral	0,21	neutral	0,26	5	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,08	medium_impact	1,03	medium_impact	-0,13	low_impact	-1,21	0,92	0,95	41,59	7,51	P	0,62	P	0,37	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6153	6153	C	G	MI.2417	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	250	84	P	A	Ccc/Gcc	-20	0	0	benign	0,16	deleterious	0	neutral	1,63	deleterious	-4,08	deleterious	-5,49	high_impact	5,24	neutral	0,68	damaging	0,06	deleterious	2,99	22,2	0,2	0,55	neutral	0,48	disease	0,81	disease	0,64	disease	0,7	4	deleterious	1	neutral	0,42	deleterious	2	neutral	0,36	medium_impact	-0,08	low_impact	-1,48	high_impact	3,74	0,66	0,9	2,92	6,76	N	0,47	N	0,76	polymorphism	0,96	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14666	14666	T	G	MI.24170	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	8	3	Y	S	tAt/tCt	-1,65	0	0	probably_damaging	1	neutral	0,26	neutral	1,75	deleterious	-3,61	deleterious	-6,56	medium_impact	3,27	neutral	0,85	damaging	0,2	deleterious	3,8	23,4	0,33	0,5	disease	0,68	disease	0,62	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,78	low_impact	-3,55	medium_impact	-0,05	medium_impact	1,6	0,33	0,8	15,93	14,48	N	0,3	N	0,73	NA	NA	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14666	14666	T	A	MI.24171	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	8	3	Y	F	tAt/tTt	-1,65	0	0	probably_damaging	1	neutral	0,54	neutral	1,84	deleterious	-3,44	deleterious	-3,4	medium_impact	2,37	neutral	0,87	neutral	0,54	deleterious	3,43	23	0,34	0,5	neutral	0,24	neutral	0,38	neutral	0,42	neutral	0,4	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,69	low_impact	-3,55	medium_impact	0,25	medium_impact	0,85	0,61	0,8	15,93	14,48	N	0,3	N	0,53	NA	NA	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14666	14666	T	C	MI.24172	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	8	3	Y	C	tAt/tGt	-1,65	0	0	probably_damaging	1	neutral	0,09	neutral	1,72	deleterious	-5,96	deleterious	-7,39	medium_impact	3,27	neutral	0,78	damaging	0,09	deleterious	3,18	22,7	0,36	0,5	disease	0,86	disease	0,66	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,79	low_impact	-3,55	medium_impact	-0,35	medium_impact	1,6	0,27	0,8	15,93	14,48	N	0,28	N	0,75	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14667	14667	A	T	MI.24173	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	7	3	Y	N	Tat/Aat	0,18	0	0	probably_damaging	1	neutral	0,22	neutral	1,74	deleterious	-4,32	deleterious	-5,76	medium_impact	2,77	neutral	0,88	neutral	0,31	deleterious	2,18	17,37	0,3	0,45	neutral	0,35	disease	0,63	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,73	low_impact	-3,55	medium_impact	-0,1	medium_impact	1,18	0,3	0,8	15,93	14,48	N	0,36	N	0,41	NA	NA	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14667	14667	A	C	MI.24174	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	7	3	Y	D	Tat/Gat	0,18	0	0	probably_damaging	1	neutral	0,12	neutral	1,72	deleterious	-4,29	deleterious	-7,31	medium_impact	3,47	neutral	0,81	damaging	0,1	deleterious	3,36	22,9	0,21	0,45	disease	0,8	disease	0,74	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,81	low_impact	-3,55	medium_impact	-0,27	medium_impact	1,77	0,37	0,8	15,93	14,48	N	0,29	N	0,82	NA	NA	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14667	14667	A	G	MI.24175	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	7	3	Y	H	Tat/Cat	0,18	0	0	probably_damaging	1	neutral	0,31	neutral	1,73	deleterious	-4,85	deleterious	-3,43	medium_impact	3,47	neutral	0,82	damaging	0,12	neutral	1,55	13,58	0,39	0,5	disease	0,63	disease	0,59	disease	0,64	disease	0,59	2	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,78	low_impact	-3,55	medium_impact	0,01	medium_impact	1,77	0,38	0,8	15,93	14,48	N	0,31	N	0,61	NA	NA	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14668	14668	C	A	MI.24176	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	6	2	M	I	atG/atT	0,87	0	0,48	benign	0,02	neutral	0,56	neutral	2,3	neutral	-0,28	neutral	-0,72	low_impact	0,92	neutral	0,89	neutral	0,94	deleterious	0,54	7,73	0,64	0,7	neutral	0,11	neutral	0,2	neutral	0,17	neutral	0,36	3	neutral	0,41	deleterious	0,77	neutral	-6	neutral	0,11	medium_impact	0,75	medium_impact	0,27	medium_impact	-0,37	0,68	0,85	41,59	7,23	N	0,45	N	0,13	NA	NA	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14668	14668	C	G	MI.24177	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	6	2	M	I	atG/atC	0,87	0	0,48	benign	0,02	neutral	0,56	neutral	2,3	neutral	-0,28	neutral	-0,72	low_impact	0,92	neutral	0,89	neutral	0,94	deleterious	0,2	4,7	0,64	0,7	neutral	0,11	neutral	0,2	neutral	0,17	neutral	0,36	3	neutral	0,41	deleterious	0,77	neutral	-6	neutral	0,11	medium_impact	0,75	medium_impact	0,27	medium_impact	-0,37	0,68	0,85	41,59	7,23	N	0,43	N	0,13	NA	NA	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14669	14669	A	G	MI.24178	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	5	2	M	T	aTg/aCg	-5,55	0	0	benign	0	neutral	0,96	neutral	2,38	deleterious	-3,75	neutral	0,3	neutral_impact	-0,02	neutral	0,98	neutral	1	neutral	-1,82	0	0,62	0,65	neutral	0,09	neutral	0,07	neutral	0,15	neutral	0,23	5	neutral	0,03	deleterious	0,98	neutral	-6	neutral	0,07	medium_impact	1,95	medium_impact	0,97	low_impact	-1,16	0,44	0,8	41,59	7,23	N	0,47	N	0,04	NA	NA	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14669	14669	A	T	MI.24179	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	5	2	M	K	aTg/aAg	-5,55	0	0	benign	0,06	neutral	1	neutral	2,24	deleterious	-4,83	deleterious	-2,62	medium_impact	2,08	neutral	0,82	neutral	0,49	neutral	1,34	12,46	0,39	0,5	neutral	0,28	disease	0,54	neutral	0,4	disease	0,53	1	neutral	0,05	deleterious	0,97	neutral	-3	neutral	0,17	medium_impact	0,3	high_impact	1,87	medium_impact	0,6	0,67	0,85	41,59	7,23	N	0,24	N	0,32	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6154	6154	C	T	MI.2418	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	251	84	P	L	cCc/cTc	7,3	1	0	benign	0,06	deleterious	0	neutral	1,53	deleterious	-7,4	deleterious	-6,86	high_impact	4,69	neutral	0,67	damaging	0,03	deleterious	4,31	24	0,21	0,55	disease	0,72	disease	0,91	disease	0,63	disease	0,74	5	deleterious	1	deleterious	0,47	deleterious	2	neutral	0,34	medium_impact	0,37	low_impact	-1,48	high_impact	3,23	0,84	0,9	2,92	6,76	P	0,51	P	0,87	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14670	14670	T	A	MI.24180	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	4	2	M	L	Atg/Ttg	-0,5	0	0	benign	0,01	neutral	0,69	neutral	2,32	neutral	-0,8	neutral	-0,65	low_impact	1,78	neutral	0,92	neutral	0,91	deleterious	0,34	6,09	0,56	0,6	neutral	0,1	neutral	0,31	neutral	0,33	neutral	0,45	1	neutral	0,29	deleterious	0,84	neutral	-6	neutral	0,1	medium_impact	1,03	medium_impact	0,4	medium_impact	0,35	0,7	0,85	41,59	7,23	N	0,34	N	0,11	NA	NA	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14670	14670	T	G	MI.24181	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	4	2	M	L	Atg/Ctg	-0,5	0	0	benign	0,01	neutral	0,69	neutral	2,32	neutral	-0,8	neutral	-0,65	low_impact	1,78	neutral	0,92	neutral	0,91	deleterious	0,22	4,85	0,56	0,6	neutral	0,1	neutral	0,31	neutral	0,33	neutral	0,45	1	neutral	0,29	deleterious	0,84	neutral	-6	neutral	0,1	medium_impact	1,03	medium_impact	0,4	medium_impact	0,35	0,7	0,85	41,59	7,23	N	0,33	N	0,11	NA	NA	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14670	14670	T	C	MI.24182	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	4	2	M	V	Atg/Gtg	-0,5	0	0	benign	0	neutral	0,52	neutral	2,34	neutral	-1,55	neutral	-0,34	low_impact	0,83	neutral	0,93	neutral	0,94	neutral	-1,09	0,01	0,71	0,75	neutral	0,12	neutral	0,22	neutral	0,18	neutral	0,35	3	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,09	medium_impact	1,95	medium_impact	0,23	medium_impact	-0,45	0,75	0,85	41,59	7,23	N	0,39	N	0,09	NA	NA	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14671	14671	C	G	MI.24183	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	3	1	M	I	atG/atC	-0,5	0	0	probably_damaging	0,96	deleterious	0	neutral	1,77	neutral	-2,02	deleterious	-3,31	NA	NA	neutral	0,83	damaging	0,08	deleterious	3,52	23,1	0,38	0,5	neutral	0,38	disease	0,52	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	4	deleterious	0,77	NA	NA	NA	NA	NA	NA	0,62	0,8	50	8,74	N	0,27	N	0,75	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14671	14671	C	A	MI.24184	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	3	1	M	I	atG/atT	-0,5	0	0	probably_damaging	0,96	deleterious	0	neutral	1,77	neutral	-2,02	deleterious	-3,31	NA	NA	neutral	0,83	damaging	0,08	deleterious	4,05	23,7	0,38	0,5	neutral	0,38	disease	0,52	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	4	deleterious	0,77	NA	NA	NA	NA	NA	NA	0,62	0,8	50	8,74	N	0,27	N	0,75	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14672	14672	A	T	MI.24185	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	2	1	M	K	aTg/aAg	3,17	0,99	0	probably_damaging	0,98	deleterious	0	neutral	1,66	deleterious	-5,05	deleterious	-5,25	NA	NA	neutral	0,77	damaging	0,06	deleterious	3,4	23	0,21	0,45	disease	0,62	disease	0,66	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	4	deleterious	0,83	NA	NA	NA	NA	NA	NA	0,43	0,8	50	8,74	N	0,42	N	0,91	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14672	14672	A	G	MI.24186	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	2	1	M	T	aTg/aCg	3,17	0,99	0	probably_damaging	0,98	deleterious	0	neutral	1,67	deleterious	-4,17	deleterious	-4,67	NA	NA	neutral	0,76	damaging	0,05	deleterious	2,92	21,9	0,27	0,45	neutral	0,4	disease	0,54	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	4	deleterious	0,79	NA	NA	NA	NA	NA	NA	0,46	0,8	50	8,74	N	0,44	N	0,61	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14673	14673	T	A	MI.24187	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	1	1	M	L	Atg/Ttg	5	1	0	probably_damaging	0,92	deleterious	0	neutral	1,89	neutral	0,37	neutral	-2,48	NA	NA	neutral	0,83	damaging	0,15	deleterious	3,37	22,9	0,26	0,45	neutral	0,28	neutral	0,48	disease	0,62	disease	0,51	0	deleterious	1	neutral	0,04	deleterious	4	deleterious	0,71	NA	NA	NA	NA	NA	NA	0,48	0,8	50	8,74	P	0,53	P	0,68	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14673	14673	T	C	MI.24188	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	1	1	M	V	Atg/Gtg	5	1	0	probably_damaging	0,96	deleterious	0	neutral	1,75	neutral	-2,32	deleterious	-3,28	NA	NA	neutral	0,75	damaging	0,05	deleterious	2,3	18,18	0,37	0,5	neutral	0,37	neutral	0,48	disease	0,69	disease	0,54	1	deleterious	1	neutral	0,02	deleterious	4	deleterious	0,75	NA	NA	NA	NA	NA	NA	0,69	0,85	50	8,74	P	0,53	P	0,75	NA	NA	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14673	14673	T	G	MI.24189	MT-ND6	I	ENSG00000198695	ENSP00000354665	ENST00000361681	NU6M_HUMAN	P03923	4541	YP_003024037.1	1	1	M	L	Atg/Ctg	5	1	0	probably_damaging	0,92	deleterious	0	neutral	1,89	neutral	0,37	neutral	-2,48	NA	NA	neutral	0,83	damaging	0,15	deleterious	3,22	22,7	0,26	0,45	neutral	0,28	neutral	0,48	disease	0,62	disease	0,51	0	deleterious	1	neutral	0,04	deleterious	4	deleterious	0,71	NA	NA	NA	NA	NA	NA	0,48	0,8	50	8,74	N	0,44	N	0,68	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6154	6154	C	G	MI.2419	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	251	84	P	R	cCc/cGc	7,3	1	0	probably_damaging	0,96	deleterious	0	neutral	1,52	deleterious	-7,63	deleterious	-6,17	high_impact	5,24	neutral	0,66	damaging	0,03	deleterious	3,54	23,1	0,13	0,55	disease	0,84	disease	0,94	disease	0,76	disease	0,87	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,89	low_impact	-2,06	low_impact	-1,48	high_impact	3,74	0,61	0,9	2,92	6,76	P	0,57	P	0,9	disease_causing	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8640	8640	C	A	MI.242	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	114	38	I	M	atC/atA	2,9	0,15	0	probably_damaging	1	neutral	0,44	neutral	4,28	neutral	-1,39	neutral	-1,66	low_impact	1,73	neutral	0,93	neutral	0,88	deleterious	2,56	19,88	0,63	0,7	disease	0,54	neutral	0,31	neutral	0,29	disease	0,58	2	deleterious	0,99	neutral	0,22	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	0,23	medium_impact	0,39	0,7	0,9	15,49	18,25	N	0,4	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6154	6154	C	A	MI.2420	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	251	84	P	H	cCc/cAc	7,3	1	0	probably_damaging	0,97	deleterious	0	neutral	1,52	deleterious	-8,6	deleterious	-6,17	high_impact	4,89	neutral	0,68	damaging	0,02	deleterious	3,91	23,5	0,16	0,55	disease	0,91	disease	0,9	disease	0,67	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-2,18	low_impact	-1,48	high_impact	3,42	0,65	0,9	2,92	6,76	P	0,61	P	0,81	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6156	6156	C	G	MI.2421	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	253	85	L	V	Cta/Gta	-14,91	0	0	probably_damaging	0,98	neutral	0,05	neutral	2,68	neutral	-2,44	neutral	-1,95	medium_impact	3,38	damaging	0,54	damaging	0,05	deleterious	3,33	22,9	0,41	0,55	neutral	0,48	disease	0,76	neutral	0,31	disease	0,57	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,78	low_impact	-2,35	medium_impact	-0,52	high_impact	2,02	0,75	0,9	3,12	6,64	N	0,28	N	0,66	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6156	6156	C	A	MI.2422	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	253	85	L	M	Cta/Ata	-14,91	0	0	probably_damaging	1	neutral	0,09	neutral	2,65	deleterious	-3,17	neutral	-1,21	medium_impact	2,3	damaging	0,51	damaging	0,11	deleterious	2,58	19,99	0,31	0,55	disease	0,68	disease	0,62	neutral	0,25	neutral	0,47	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,77	low_impact	-3,58	medium_impact	-0,37	medium_impact	1,03	0,84	0,9	3,12	6,64	N	0,34	N	0,59	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6157	6157	T	G	MI.2423	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	254	85	L	R	cTa/cGa	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,78	deleterious	-3,16	deleterious	-4,05	high_impact	5	damaging	0,53	damaging	0,04	deleterious	4,06	23,7	0,13	0,55	disease	0,83	disease	0,95	disease	0,71	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,49	0,9	3,12	6,64	P	0,62	P	0,9	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6157	6157	T	A	MI.2424	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	254	85	L	Q	cTa/cAa	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-3,77	deleterious	-4,02	high_impact	5	damaging	0,55	damaging	0,05	deleterious	3,98	23,6	0,14	0,55	disease	0,66	disease	0,86	disease	0,59	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,77	0,9	3,12	6,64	P	0,62	P	0,82	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6157	6157	T	C	MI.2425	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	254	85	L	P	cTa/cCa	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-4,99	deleterious	-4,73	high_impact	4,32	damaging	0,45	damaging	0,04	deleterious	3,81	23,4	0,16	0,55	disease	0,88	disease	0,89	disease	0,72	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	2,89	0,59	0,9	3,12	6,64	N	0,35	N	0,83	disease_causing	0,99	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6159	6159	A	G	MI.2426	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	256	86	M	V	Ata/Gta	-2,65	0	0	probably_damaging	0,97	deleterious	0	neutral	2,87	neutral	-1,15	deleterious	-2,71	high_impact	4,68	damaging	0,6	damaging	0,09	deleterious	2,74	21,1	0,44	0,55	neutral	0,44	disease	0,88	disease	0,69	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,78	low_impact	-2,18	low_impact	-1,48	high_impact	3,22	0,67	0,9	1,95	6,66	N	0,5	N	0,88	polymorphism	0,92	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6159	6159	A	T	MI.2427	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	256	86	M	L	Ata/Tta	-2,65	0	0	probably_damaging	0,95	neutral	0,11	neutral	2,99	neutral	-0,03	neutral	-1,99	medium_impact	2,31	neutral	0,64	damaging	0,07	deleterious	3,29	22,8	0,4	0,55	neutral	0,32	disease	0,75	neutral	0,41	disease	0,51	0	neutral	0,98	neutral	0,08	deleterious	1	deleterious	0,73	low_impact	-1,96	medium_impact	-0,31	medium_impact	1,03	0,64	0,9	1,95	6,66	N	0,27	N	0,61	polymorphism	0,93	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6159	6159	A	C	MI.2428	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	256	86	M	L	Ata/Cta	-2,65	0	0	probably_damaging	0,95	neutral	0,11	neutral	2,99	neutral	-0,03	neutral	-1,99	medium_impact	2,31	neutral	0,64	damaging	0,07	deleterious	3,18	22,7	0,4	0,55	neutral	0,32	disease	0,75	neutral	0,41	disease	0,51	0	neutral	0,98	neutral	0,08	deleterious	1	deleterious	0,73	low_impact	-1,96	medium_impact	-0,31	medium_impact	1,03	0,64	0,9	1,95	6,66	N	0,27	N	0,61	polymorphism	0,93	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6160	6160	T	C	MI.2429	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	257	86	M	T	aTa/aCa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,88	neutral	-1,02	deleterious	-4,1	high_impact	4,22	neutral	0,63	damaging	0,11	deleterious	2,94	22	0,28	0,55	neutral	0,45	disease	0,9	disease	0,68	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,8	0,35	0,9	1,95	6,66	P	0,49	N	0,79	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8640	8640	C	G	MI.243	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	114	38	I	M	atC/atG	2,9	0,15	0	probably_damaging	1	neutral	0,44	neutral	4,28	neutral	-1,39	neutral	-1,66	low_impact	1,73	neutral	0,93	neutral	0,88	deleterious	2,08	16,74	0,63	0,7	disease	0,54	neutral	0,31	neutral	0,29	disease	0,58	2	deleterious	0,99	neutral	0,22	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	0,23	medium_impact	0,39	0,7	0,9	15,49	18,25	N	0,4	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6160	6160	T	A	MI.2430	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	257	86	M	K	aTa/aAa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,8	neutral	-2,38	deleterious	-4,12	high_impact	5,03	damaging	0,57	damaging	0,06	deleterious	4	23,6	0,14	0,55	neutral	0,4	disease	0,94	disease	0,75	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,55	0,59	0,9	1,95	6,66	P	0,68	P	0,93	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6161	6161	A	T	MI.2431	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	258	86	M	I	atA/atT	5,91	1	0	probably_damaging	0,98	deleterious	0	neutral	2,84	neutral	-1,6	deleterious	-2,7	high_impact	3,71	damaging	0,52	damaging	0,1	deleterious	3,39	23	0,4	0,55	disease	0,5	disease	0,87	neutral	0,46	disease	0,51	0	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,35	low_impact	-1,48	high_impact	2,33	0,73	0,9	1,95	6,66	P	0,51	P	0,87	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6161	6161	A	C	MI.2432	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	258	86	M	I	atA/atC	5,91	1	0	probably_damaging	0,98	deleterious	0	neutral	2,84	neutral	-1,6	deleterious	-2,7	high_impact	3,71	damaging	0,52	damaging	0,1	deleterious	3,33	22,9	0,4	0,55	disease	0,5	disease	0,87	neutral	0,46	disease	0,51	0	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,35	low_impact	-1,48	high_impact	2,33	0,73	0,9	1,95	6,66	P	0,51	P	0,87	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6162	6162	A	G	MI.2433	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	259	87	I	V	Atc/Gtc	0,36	0,98	0	probably_damaging	0,92	deleterious	0,04	neutral	2,7	neutral	-1,61	neutral	-0,67	medium_impact	2,63	neutral	0,65	damaging	0,15	deleterious	2,91	21,9	0,63	0,65	neutral	0,34	neutral	0,44	neutral	0,22	neutral	0,48	0	deleterious	0,99	neutral	0,06	deleterious	5	deleterious	0,59	low_impact	-1,76	medium_impact	-0,58	medium_impact	1,33	0,39	0,9	2,53	6,72	N	0,48	N	0,23	disease_causing	0,57	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6162	6162	A	C	MI.2434	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	259	87	I	L	Atc/Ctc	0,36	0,98	0	probably_damaging	0,97	neutral	0,94	neutral	2,87	neutral	-0,89	neutral	0,55	neutral_impact	-0,29	neutral	0,65	neutral	0,33	neutral	1,02	10,76	0,43	0,55	neutral	0,29	neutral	0,15	neutral	0,13	neutral	0,27	5	neutral	0,96	deleterious	0,49	neutral	-2	deleterious	0,58	low_impact	-2,18	medium_impact	0,86	low_impact	-1,37	0,72	0,9	2,53	6,72	N	0,4	N	0,61	disease_causing	0,76	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6162	6162	A	T	MI.2435	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	259	87	I	F	Atc/Ttc	0,36	0,98	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-3,31	neutral	-1,78	high_impact	4,3	neutral	0,62	damaging	0,1	deleterious	3,68	23,3	0,3	0,55	disease	0,81	disease	0,77	disease	0,55	disease	0,75	5	deleterious	1	deleterious	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,87	0,67	0,9	2,53	6,72	N	0,47	N	0,85	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6163	6163	T	G	MI.2436	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	260	87	I	S	aTc/aGc	6,83	1	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-3,29	deleterious	-3,15	medium_impact	3,33	neutral	0,68	damaging	0,18	deleterious	4,22	23,9	0,17	0,55	disease	0,88	disease	0,82	disease	0,55	disease	0,77	5	deleterious	1	deleterious	0	deleterious	5	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	medium_impact	1,98	0,46	0,9	2,53	6,72	N	0,45	N	0,62	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6163	6163	T	C	MI.2437	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	260	87	I	T	aTc/aCc	6,83	1	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-3,03	neutral	-2,47	high_impact	3,96	neutral	0,64	damaging	0,15	deleterious	3,41	23	0,29	0,55	disease	0,79	disease	0,7	disease	0,54	disease	0,68	4	deleterious	1	deleterious	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,56	0,46	0,9	2,53	6,72	P	0,47	N	0,76	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6163	6163	T	A	MI.2438	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	260	87	I	N	aTc/aAc	6,83	1	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-4,31	deleterious	-3,85	high_impact	3,96	neutral	0,62	damaging	0,12	deleterious	4,46	24,2	0,15	0,55	disease	0,93	disease	0,86	disease	0,54	disease	0,82	6	deleterious	1	deleterious	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,56	0,48	0,9	2,53	6,72	N	0,47	N	0,94	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6164	6164	C	A	MI.2439	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	261	87	I	M	atC/atA	5,91	1	0,03	probably_damaging	1	neutral	0,14	neutral	2,59	deleterious	-3,06	neutral	-0,53	low_impact	1,7	neutral	0,65	damaging	0,17	deleterious	3,75	23,3	0,34	0,55	disease	0,78	disease	0,57	neutral	0,2	disease	0,51	0	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,78	low_impact	-3,58	medium_impact	-0,25	medium_impact	0,47	0,75	0,9	2,53	6,72	P	0,53	P	0,76	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8641	8641	A	C	MI.244	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	115	39	N	H	Aac/Cac	-8,89	0	0	probably_damaging	1	neutral	0,12	neutral	4,32	neutral	-1,95	deleterious	-3,24	low_impact	1,77	neutral	0,89	neutral	0,52	deleterious	2,92	22	0,73	0,75	disease	0,65	disease	0,56	neutral	0,34	disease	0,5	0	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	-0,2	medium_impact	0,42	0,57	0,9	18,58	19,57	N	0,43	N	0,44	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6164	6164	C	G	MI.2440	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	261	87	I	M	atC/atG	5,91	1	0,03	probably_damaging	1	neutral	0,14	neutral	2,59	deleterious	-3,06	neutral	-0,53	low_impact	1,7	neutral	0,65	damaging	0,17	deleterious	3,25	22,8	0,34	0,55	disease	0,78	disease	0,57	neutral	0,2	disease	0,51	0	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,78	low_impact	-3,58	medium_impact	-0,25	medium_impact	0,47	0,75	0,9	2,53	6,72	P	0,52	P	0,76	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6165	6165	G	T	MI.2441	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	262	88	G	C	Ggt/Tgt	-1,72	0	0	probably_damaging	1	deleterious	0,01	neutral	2,45	deleterious	-6,39	deleterious	-6,21	high_impact	3,92	damaging	0,4	damaging	0,01	deleterious	4,03	23,6	0,18	0,55	disease	0,96	disease	0,9	disease	0,53	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,58	medium_impact	-0,92	high_impact	2,52	0,31	0,9	2,14	6,64	N	0,36	N	0,98	disease_causing	0,97	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6165	6165	G	C	MI.2442	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	262	88	G	R	Ggt/Cgt	-1,72	0	0	probably_damaging	1	deleterious	0	neutral	2,54	neutral	-2,73	deleterious	-5,52	high_impact	5,08	damaging	0,45	damaging	0,01	deleterious	3,82	23,4	0,18	0,55	disease	0,78	disease	0,92	disease	0,74	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,59	0,63	0,9	2,14	6,64	P	0,61	P	0,95	disease_causing	0,95	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6165	6165	G	A	MI.2443	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	262	88	G	S	Ggt/Agt	-1,72	0	0	probably_damaging	1	deleterious	0,02	neutral	2,54	neutral	-2,75	deleterious	-4,07	medium_impact	2,45	damaging	0,47	damaging	0,02	deleterious	4,01	23,6	0,23	0,55	disease	0,81	disease	0,81	neutral	0,44	disease	0,59	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,16	0,59	0,9	2,14	6,64	N	0,29	N	0,73	disease_causing	0,9	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6166	6166	G	A	MI.2444	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	263	88	G	D	gGt/gAt	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,54	neutral	-2,79	deleterious	-4,82	high_impact	4,53	damaging	0,36	damaging	0,01	deleterious	3,67	23,3	0,17	0,55	disease	0,82	disease	0,89	disease	0,72	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,08	0,4	0,9	2,14	6,64	P	0,69	P	0,97	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6166	6166	G	C	MI.2445	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	263	88	G	A	gGt/gCt	5,22	1	0	probably_damaging	1	deleterious	0,01	neutral	2,5	deleterious	-3,49	deleterious	-4,1	medium_impact	3,45	damaging	0,59	damaging	0,08	deleterious	3,09	22,5	0,23	0,55	disease	0,8	disease	0,77	disease	0,58	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,58	medium_impact	-0,92	high_impact	2,09	0,52	0,9	2,14	6,64	N	0,41	N	0,64	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6166	6166	G	T	MI.2446	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	263	88	G	V	gGt/gTt	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,47	deleterious	-4,69	deleterious	-6,22	high_impact	4,38	damaging	0,48	damaging	0,02	deleterious	3,76	23,3	0,16	0,55	disease	0,91	disease	0,91	disease	0,62	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,95	0,39	0,9	2,14	6,64	N	0,46	N	0,93	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6168	6168	G	T	MI.2447	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	265	89	A	S	Gcc/Tcc	-7,51	0	0	probably_damaging	1	neutral	0,11	neutral	2,74	neutral	-2,19	neutral	-1,85	low_impact	1,56	damaging	0,58	damaging	0,23	deleterious	3,6	23,2	0,26	0,55	neutral	0,27	disease	0,65	neutral	0,22	neutral	0,42	2	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,76	low_impact	-3,58	medium_impact	-0,31	medium_impact	0,34	0,61	0,9	6,04	10,67	N	0,37	N	0,64	polymorphism	0,98	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6168	6168	G	A	MI.2448	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	265	89	A	T	Gcc/Acc	-7,51	0	0	probably_damaging	1	deleterious	0,01	neutral	2,79	neutral	-2,81	deleterious	-2,5	medium_impact	3,31	neutral	0,61	damaging	0,17	deleterious	4,13	23,8	0,27	0,55	disease	0,64	disease	0,8	neutral	0,4	disease	0,54	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,96	0,61	0,9	6,04	10,67	N	0,3	N	0,2	polymorphism	0,96	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6168	6168	G	C	MI.2449	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	265	89	A	P	Gcc/Ccc	-7,51	0	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-4,5	deleterious	-3,34	high_impact	4,89	damaging	0,56	damaging	0,13	deleterious	3,78	23,4	0,13	0,55	disease	0,81	disease	0,86	disease	0,55	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,42	0,63	0,9	6,04	10,67	P	0,64	P	0,85	polymorphism	0,88	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8641	8641	A	T	MI.245	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	115	39	N	Y	Aac/Tac	-8,89	0	0	probably_damaging	1	neutral	0,2	neutral	4,31	neutral	-2,39	deleterious	-5,11	medium_impact	2,54	neutral	0,89	neutral	0,46	deleterious	3,52	23,1	0,5	0,65	disease	0,64	disease	0,7	neutral	0,49	disease	0,51	0	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	-0,05	medium_impact	1,08	0,49	0,9	18,58	19,57	N	0,41	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6169	6169	C	G	MI.2450	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	266	89	A	G	gCc/gGc	7,53	1	0	probably_damaging	0,99	deleterious	0,03	neutral	2,68	deleterious	-3,57	deleterious	-2,69	high_impact	3,8	neutral	0,61	damaging	0,16	deleterious	3,92	23,5	0,21	0,55	disease	0,66	disease	0,67	disease	0,53	disease	0,51	0	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-2,64	medium_impact	-0,65	high_impact	2,41	0,66	0,9	6,04	10,67	P	0,52	P	0,56	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6169	6169	C	A	MI.2451	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	266	89	A	D	gCc/gAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,66	deleterious	-3,28	deleterious	-3,96	high_impact	4,55	neutral	0,65	damaging	0,12	deleterious	4,39	24,1	0,12	0,55	disease	0,74	disease	0,88	disease	0,7	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,1	0,5	0,9	6,04	10,67	P	0,55	P	0,89	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6169	6169	C	T	MI.2452	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	266	89	A	V	gCc/gTc	7,53	1	0	probably_damaging	1	neutral	0,05	neutral	2,75	deleterious	-3,36	deleterious	-2,62	medium_impact	2,66	damaging	0,49	damaging	0,14	deleterious	4,41	24,1	0,2	0,55	disease	0,59	disease	0,82	neutral	0,31	disease	0,63	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,82	low_impact	-3,58	medium_impact	-0,52	medium_impact	1,36	0,68	0,9	6,04	10,67	P	0,55	P	0,75	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6171	6171	C	G	MI.2453	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	268	90	P	A	Ccc/Gcc	-6,81	0	0	probably_damaging	1	deleterious	0	neutral	2,77	neutral	-2,33	deleterious	-5,45	medium_impact	3,34	neutral	0,68	damaging	0,06	deleterious	3,03	22,3	0,32	0,55	neutral	0,42	disease	0,75	disease	0,58	disease	0,62	2	deleterious	1	neutral	0	deleterious	5	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	medium_impact	1,99	0,74	0,9	2,92	8,39	N	0,25	N	0,76	polymorphism	0,96	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6171	6171	C	T	MI.2454	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	268	90	P	S	Ccc/Tcc	-6,81	0	0	probably_damaging	1	deleterious	0	neutral	2,86	neutral	-1,08	deleterious	-5,49	high_impact	3,68	neutral	0,68	damaging	0,04	deleterious	3,84	23,4	0,46	0,55	neutral	0,35	disease	0,83	disease	0,55	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,3	0,31	0,9	2,92	8,39	N	0,27	N	0,85	polymorphism	0,93	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6171	6171	C	A	MI.2455	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	268	90	P	T	Ccc/Acc	-6,81	0	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-2,59	deleterious	-5,5	high_impact	4,41	neutral	0,69	damaging	0,04	deleterious	3,63	23,2	0,31	0,55	neutral	0,36	disease	0,86	disease	0,65	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,97	0,7	0,9	2,92	8,39	N	0,37	N	0,8	polymorphism	0,94	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6172	6172	C	A	MI.2456	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	269	90	P	H	cCc/cAc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,75	neutral	-2,94	deleterious	-6,22	high_impact	5,1	neutral	0,68	damaging	0,02	deleterious	3,92	23,5	0,31	0,55	disease	0,61	disease	0,88	disease	0,76	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,61	0,66	0,9	2,92	8,39	P	0,71	P	0,81	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6172	6172	C	G	MI.2457	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	269	90	P	R	cCc/cGc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,94	neutral	-0,34	deleterious	-6,2	high_impact	3,75	neutral	0,66	damaging	0,03	deleterious	3,54	23,1	0,24	0,55	neutral	0,17	disease	0,92	disease	0,77	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,36	0,66	0,9	2,92	8,39	P	0,51	P	0,9	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6172	6172	C	T	MI.2458	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	269	90	P	L	cCc/cTc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,73	deleterious	-3,89	deleterious	-6,9	high_impact	4,55	neutral	0,69	damaging	0,02	deleterious	4,32	24	0,35	0,55	disease	0,56	disease	0,88	disease	0,65	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,1	0,82	0,9	2,92	8,39	P	0,53	P	0,87	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6174	6174	G	C	MI.2459	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	271	91	D	H	Gat/Cat	-11,44	0	0	probably_damaging	0,99	deleterious	0	neutral	2,18	deleterious	-4,62	deleterious	-4,98	high_impact	5,24	damaging	0,59	damaging	0,1	deleterious	3,66	23,2	0,25	0,55	disease	0,85	disease	0,86	disease	0,82	disease	0,86	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,64	low_impact	-1,48	high_impact	3,74	0,54	0,9	1,56	8,43	P	0,66	P	0,97	polymorphism	0,82	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8641	8641	A	G	MI.246	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	115	39	N	D	Aac/Gac	-8,89	0	0	probably_damaging	0,99	neutral	0,15	neutral	4,35	neutral	-0,84	deleterious	-2,68	low_impact	1,77	neutral	0,93	neutral	0,85	deleterious	2,56	19,85	0,82	0,85	neutral	0,33	disease	0,5	neutral	0,41	neutral	0,47	1	deleterious	0,99	neutral	0,08	neutral	-2	deleterious	0,69	low_impact	-2,65	medium_impact	-0,13	medium_impact	0,42	0,63	0,9	18,58	19,57	N	0,46	N	0,61	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6174	6174	G	T	MI.2460	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	271	91	D	Y	Gat/Tat	-11,44	0	0	probably_damaging	0,99	deleterious	0	neutral	2,16	deleterious	-5,9	deleterious	-6,41	high_impact	5,24	damaging	0,51	damaging	0,13	deleterious	3,9	23,5	0,17	0,55	disease	0,91	disease	0,91	disease	0,78	disease	0,86	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,91	low_impact	-2,64	low_impact	-1,48	high_impact	3,74	0,41	0,9	1,56	8,43	P	0,57	P	0,94	polymorphism	0,69	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6174	6174	G	A	MI.2461	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	271	91	D	N	Gat/Aat	-11,44	0	0	possibly_damaging	0,77	deleterious	0	neutral	2,22	deleterious	-3,36	deleterious	-3,56	high_impact	4,69	damaging	0,48	damaging	0,11	deleterious	4,14	23,8	0,45	0,55	disease	0,66	disease	0,8	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,12	deleterious	5	deleterious	0,77	low_impact	-1,25	low_impact	-1,48	high_impact	3,23	0,79	0,9	1,56	8,43	P	0,57	P	0,89	polymorphism	0,96	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6175	6175	A	C	MI.2462	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	272	91	D	A	gAt/gCt	7,3	1	0	possibly_damaging	0,67	deleterious	0	neutral	2,21	deleterious	-3,64	deleterious	-5,7	high_impact	4,89	neutral	0,67	damaging	0,13	deleterious	3,67	23,2	0,21	0,55	disease	0,73	disease	0,84	disease	0,75	disease	0,78	6	deleterious	1	neutral	0,17	deleterious	5	deleterious	0,75	low_impact	-1,05	low_impact	-1,48	high_impact	3,42	0,51	0,9	1,56	8,43	P	0,68	P	0,85	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6175	6175	A	T	MI.2463	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	272	91	D	V	gAt/gTt	7,3	1	0	benign	0,14	deleterious	0	neutral	2,17	deleterious	-5,03	deleterious	-6,41	high_impact	5,24	damaging	0,53	damaging	0,12	deleterious	3,82	23,4	0,2	0,55	disease	0,86	disease	0,93	disease	0,75	disease	0,85	7	deleterious	1	neutral	0,43	deleterious	2	neutral	0,41	medium_impact	-0,01	low_impact	-1,48	high_impact	3,74	0,31	0,9	1,56	8,43	P	0,58	P	0,93	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6175	6175	A	G	MI.2464	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	272	91	D	G	gAt/gGt	7,3	1	0	possibly_damaging	0,75	deleterious	0	neutral	2,18	deleterious	-4,44	deleterious	-4,98	high_impact	5,24	damaging	0,54	damaging	0,13	deleterious	4,01	23,6	0,25	0,55	disease	0,76	disease	0,84	disease	0,76	disease	0,8	6	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,79	low_impact	-1,21	low_impact	-1,48	high_impact	3,74	0,47	0,9	1,56	8,43	P	0,68	P	0,85	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6176	6176	T	G	MI.2465	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	273	91	D	E	gaT/gaG	6,83	1	0	benign	0,22	deleterious	0,04	neutral	2,29	neutral	-2,4	deleterious	-2,85	high_impact	3,69	damaging	0,52	damaging	0,12	deleterious	3,84	23,4	0,35	0,55	neutral	0,48	disease	0,8	disease	0,66	disease	0,71	4	neutral	0,95	neutral	0,41	deleterious	2	neutral	0,43	medium_impact	-0,24	medium_impact	-0,58	high_impact	2,31	0,64	0,9	1,56	8,43	P	0,53	P	0,65	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6176	6176	T	A	MI.2466	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	273	91	D	E	gaT/gaA	6,83	1	0	benign	0,22	deleterious	0,04	neutral	2,29	neutral	-2,4	deleterious	-2,85	high_impact	3,69	damaging	0,52	damaging	0,12	deleterious	3,96	23,6	0,35	0,55	neutral	0,48	disease	0,8	disease	0,66	disease	0,71	4	neutral	0,95	neutral	0,41	deleterious	2	neutral	0,43	medium_impact	-0,24	medium_impact	-0,58	high_impact	2,31	0,64	0,9	1,56	8,43	P	0,53	P	0,65	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6177	6177	A	T	MI.2467	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	274	92	M	L	Atg/Ttg	-4,96	0	0	probably_damaging	0,95	neutral	0,09	neutral	3,34	neutral	2,04	neutral	-2,14	medium_impact	3,1	damaging	0,58	neutral	0,47	deleterious	3,22	22,7	0,45	0,55	neutral	0,18	disease	0,74	disease	0,6	disease	0,62	2	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,68	low_impact	-1,96	medium_impact	-0,37	medium_impact	1,76	0,72	0,9	2,14	6,66	N	0,39	N	0,61	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6177	6177	A	G	MI.2468	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	274	92	M	V	Atg/Gtg	-4,96	0	0	probably_damaging	0,97	deleterious	0	neutral	2,84	neutral	0,22	deleterious	-2,86	medium_impact	2,97	damaging	0,47	neutral	0,44	deleterious	2,59	20,1	0,48	0,55	neutral	0,17	disease	0,83	disease	0,61	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,72	low_impact	-2,18	low_impact	-1,48	medium_impact	1,64	0,76	0,9	2,14	6,66	N	0,44	N	0,88	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6177	6177	A	C	MI.2469	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	274	92	M	L	Atg/Ctg	-4,96	0	0	probably_damaging	0,95	neutral	0,09	neutral	3,34	neutral	2,04	neutral	-2,14	medium_impact	3,1	damaging	0,58	neutral	0,47	deleterious	3,22	22,7	0,45	0,55	neutral	0,18	disease	0,74	disease	0,6	disease	0,62	2	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,68	low_impact	-1,96	medium_impact	-0,37	medium_impact	1,76	0,72	0,9	2,14	6,66	N	0,39	N	0,61	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8642	8642	A	T	MI.247	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	116	39	N	I	aAc/aTc	1,98	0	0	probably_damaging	1	neutral	0,14	neutral	4,33	neutral	-1,6	deleterious	-5,9	low_impact	1,59	neutral	0,86	neutral	0,49	deleterious	3,85	23,4	0,5	0,65	disease	0,59	disease	0,7	neutral	0,42	disease	0,52	0	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	-0,15	medium_impact	0,27	0,33	0,9	18,58	19,57	N	0,34	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6178	6178	T	C	MI.2470	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	275	92	M	T	aTg/aCg	8,69	1	0	probably_damaging	1	deleterious	0,01	neutral	2,62	neutral	-2,91	deleterious	-4,29	high_impact	4,58	damaging	0,6	neutral	0,42	deleterious	2,95	22,1	0,38	0,55	neutral	0,3	disease	0,87	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,58	medium_impact	-0,92	high_impact	3,13	0,53	0,9	2,14	6,66	P	0,49	N	0,79	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6178	6178	T	A	MI.2471	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	275	92	M	K	aTg/aAg	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-4,77	deleterious	-4,3	high_impact	5,13	damaging	0,56	neutral	0,42	deleterious	3,88	23,5	0,16	0,55	disease	0,54	disease	0,91	disease	0,76	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,64	0,48	0,9	2,14	6,66	P	0,7	P	0,93	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6179	6179	G	C	MI.2472	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	276	92	M	I	atG/atC	7,53	1	0,04	probably_damaging	0,98	deleterious	0	neutral	2,8	neutral	-0,07	deleterious	-2,86	high_impact	4,16	damaging	0,53	neutral	0,53	deleterious	3,56	23,1	0,42	0,55	neutral	0,28	disease	0,86	disease	0,6	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,35	low_impact	-1,48	high_impact	2,74	0,82	0,9	2,14	6,66	P	0,52	P	0,87	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6179	6179	G	T	MI.2473	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	276	92	M	I	atG/atT	7,53	1	0,04	probably_damaging	0,98	deleterious	0	neutral	2,8	neutral	-0,07	deleterious	-2,86	high_impact	4,16	damaging	0,53	neutral	0,53	deleterious	3,66	23,2	0,42	0,55	neutral	0,28	disease	0,86	disease	0,6	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,35	low_impact	-1,48	high_impact	2,74	0,82	0,9	2,14	6,66	P	0,53	P	0,87	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6180	6180	G	C	MI.2474	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	277	93	A	P	Gcg/Ccg	-0,11	0,39	0	probably_damaging	1	deleterious	0	neutral	2,68	deleterious	-3,97	deleterious	-3,56	high_impact	4,58	damaging	0,5	damaging	0,15	deleterious	3,75	23,3	0,12	0,55	disease	0,58	disease	0,83	disease	0,6	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,13	0,77	0,9	2,73	8,45	N	0,46	N	0,85	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6180	6180	G	T	MI.2475	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	277	93	A	S	Gcg/Tcg	-0,11	0,39	0	probably_damaging	1	neutral	0,21	neutral	2,72	neutral	-2,56	neutral	-1,97	medium_impact	2,62	neutral	0,63	damaging	0,18	deleterious	3,6	23,2	0,31	0,55	neutral	0,46	disease	0,67	neutral	0,26	neutral	0,44	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,79	low_impact	-3,58	medium_impact	-0,13	medium_impact	1,32	0,75	0,9	2,73	8,45	N	0,35	N	0,64	disease_causing	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6180	6180	G	A	MI.2476	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	277	93	A	T	Gcg/Acg	-0,11	0,39	0	probably_damaging	1	deleterious	0,01	neutral	2,7	deleterious	-3,05	deleterious	-2,78	high_impact	4,32	damaging	0,54	damaging	0,15	deleterious	4,14	23,8	0,38	0,55	disease	0,62	disease	0,82	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,58	medium_impact	-0,92	high_impact	2,89	0,66	0,9	2,73	8,45	N	0,32	N	0,2	disease_causing	0,99	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6181	6181	C	G	MI.2477	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	278	93	A	G	gCg/gGg	6,14	1	0	probably_damaging	0,99	deleterious	0	neutral	2,68	deleterious	-3,38	deleterious	-2,83	high_impact	4,16	damaging	0,45	damaging	0,19	deleterious	3,86	23,5	0,22	0,55	disease	0,55	disease	0,7	disease	0,6	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,64	low_impact	-1,48	high_impact	2,74	0,72	0,9	2,73	8,45	P	0,61	P	0,56	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6181	6181	C	T	MI.2478	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	278	93	A	V	gCg/gTg	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,79	neutral	-2,29	deleterious	-2,89	high_impact	3,58	damaging	0,49	damaging	0,12	deleterious	4,41	24,1	0,3	0,55	disease	0,72	disease	0,83	disease	0,62	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,21	0,73	0,9	2,73	8,45	P	0,54	P	0,75	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6181	6181	C	A	MI.2479	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	278	93	A	E	gCg/gAg	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,68	neutral	-2,52	deleterious	-3,52	high_impact	5,12	damaging	0,53	damaging	0,15	deleterious	4,37	24,1	0,11	0,55	neutral	0,41	disease	0,84	disease	0,73	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,63	0,52	0,9	2,73	8,45	P	0,72	P	0,76	disease_causing	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8642	8642	A	C	MI.248	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	116	39	N	T	aAc/aCc	1,98	0	0	probably_damaging	0,99	neutral	0,3	neutral	4,35	neutral	-0,69	deleterious	-3,1	neutral_impact	0,62	neutral	0,92	neutral	0,96	deleterious	1,91	15,63	0,63	0,7	neutral	0,5	neutral	0,34	neutral	0,2	neutral	0,33	3	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,68	low_impact	-2,65	medium_impact	0,08	medium_impact	-0,57	0,51	0,9	18,58	19,57	N	0,41	N	0,37	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6183	6183	T	G	MI.2480	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	280	94	F	V	Ttt/Gtt	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,56	neutral	-2,26	deleterious	-5,13	high_impact	5,2	neutral	0,75	damaging	0,07	deleterious	4	23,6	0,2	0,55	disease	0,71	disease	0,89	disease	0,8	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,7	0,53	0,9	1,56	6,6	P	0,71	P	0,84	disease_causing	0,86	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6183	6183	T	A	MI.2481	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	280	94	F	I	Ttt/Att	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,54	neutral	-2,51	deleterious	-4,41	high_impact	5,2	neutral	0,78	damaging	0,07	deleterious	4,31	24	0,17	0,55	disease	0,73	disease	0,91	disease	0,79	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,7	0,61	0,9	1,56	6,6	P	0,73	P	0,88	disease_causing	0,75	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6183	6183	T	C	MI.2482	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	280	94	F	L	Ttt/Ctt	-2,19	0	0	probably_damaging	0,99	neutral	0,07	neutral	2,64	neutral	-1,79	deleterious	-4,41	high_impact	3,63	neutral	0,77	damaging	0,05	deleterious	3,92	23,5	0,31	0,55	disease	0,51	disease	0,81	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,77	low_impact	-2,64	medium_impact	-0,43	high_impact	2,25	0,76	0,9	1,56	6,6	N	0,35	N	0,83	disease_causing	0,77	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6184	6184	T	C	MI.2483	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	281	94	F	S	tTt/tCt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,65	neutral	-1,94	deleterious	-5,88	high_impact	5,2	neutral	0,79	damaging	0,08	deleterious	4,11	23,8	0,18	0,55	disease	0,8	disease	0,87	disease	0,77	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,7	0,5	0,9	1,56	6,6	P	0,72	P	0,84	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6184	6184	T	G	MI.2484	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	281	94	F	C	tTt/tGt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-4,89	deleterious	-5,88	high_impact	5,2	neutral	0,8	damaging	0,06	deleterious	4,01	23,6	0,19	0,55	disease	0,91	disease	0,88	disease	0,81	disease	0,89	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,7	0,41	0,9	1,56	6,6	P	0,69	P	0,91	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6184	6184	T	A	MI.2485	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	281	94	F	Y	tTt/tAt	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,53	neutral	-2,98	neutral	-2,12	medium_impact	2,9	neutral	0,78	damaging	0,06	deleterious	4,16	23,8	0,28	0,55	neutral	0,3	disease	0,78	disease	0,76	disease	0,63	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,73	low_impact	-2,64	low_impact	-1,48	medium_impact	1,58	0,7	0,9	1,56	6,6	N	0,47	N	0,59	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6185	6185	T	G	MI.2486	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	282	94	F	L	ttT/ttG	5,91	1	0,02	probably_damaging	0,99	neutral	0,07	neutral	2,64	neutral	-1,79	deleterious	-4,41	high_impact	3,63	neutral	0,77	damaging	0,05	deleterious	4,27	23,9	0,31	0,55	disease	0,51	disease	0,81	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,77	low_impact	-2,64	medium_impact	-0,43	high_impact	2,25	0,76	0,9	1,56	6,6	P	0,6	P	0,83	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6185	6185	T	A	MI.2487	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	282	94	F	L	ttT/ttA	5,91	1	0,02	probably_damaging	0,99	neutral	0,07	neutral	2,64	neutral	-1,79	deleterious	-4,41	high_impact	3,63	neutral	0,77	damaging	0,05	deleterious	4,4	24,1	0,31	0,55	disease	0,51	disease	0,81	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,77	low_impact	-2,64	medium_impact	-0,43	high_impact	2,25	0,76	0,9	1,56	6,6	P	0,6	P	0,83	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6186	6186	C	T	MI.2488	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	283	95	P	S	Ccc/Tcc	-3,11	0	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-3,06	deleterious	-6,05	high_impact	5,26	neutral	0,69	neutral	0,44	deleterious	3,83	23,4	0,27	0,55	disease	0,72	disease	0,84	disease	0,68	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,24	0,9	1,75	6,71	P	0,65	P	0,85	disease_causing	0,99	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6186	6186	C	G	MI.2489	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	283	95	P	A	Ccc/Gcc	-3,11	0	0	probably_damaging	1	deleterious	0	neutral	2,54	neutral	-2,89	deleterious	-6,05	high_impact	4,07	neutral	0,67	neutral	0,47	deleterious	3,02	22,3	0,22	0,55	disease	0,68	disease	0,75	disease	0,62	disease	0,62	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,66	0,62	0,9	1,75	6,71	N	0,36	N	0,76	disease_causing	0,99	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8642	8642	A	G	MI.249	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	116	39	N	S	aAc/aGc	1,98	0	0	probably_damaging	0,99	neutral	0,65	neutral	4,42	neutral	0,31	deleterious	-2,6	neutral_impact	0,66	neutral	0,93	neutral	0,98	neutral	1,56	13,66	0,73	0,75	neutral	0,36	neutral	0,35	neutral	0,23	neutral	0,46	1	deleterious	0,99	neutral	0,33	neutral	-2	deleterious	0,69	low_impact	-2,65	medium_impact	0,44	medium_impact	-0,53	0,2	0,9	18,58	19,57	N	0,32	N	0,04	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6186	6186	C	A	MI.2490	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	283	95	P	T	Ccc/Acc	-3,11	0	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-3,39	deleterious	-6,05	high_impact	5,26	neutral	0,62	neutral	0,33	deleterious	3,62	23,2	0,24	0,55	disease	0,77	disease	0,87	disease	0,68	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,62	0,9	1,75	6,71	P	0,65	P	0,8	disease_causing	0,99	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6187	6187	C	A	MI.2491	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	284	95	P	H	cCc/cAc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-4,63	deleterious	-6,81	high_impact	5,26	neutral	0,63	neutral	0,33	deleterious	3,93	23,5	0,19	0,55	disease	0,94	disease	0,88	disease	0,79	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,47	0,9	1,75	6,71	P	0,7	P	0,81	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6187	6187	C	G	MI.2492	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	284	95	P	R	cCc/cGc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,54	neutral	-2,92	deleterious	-6,81	high_impact	5,26	damaging	0,6	neutral	0,33	deleterious	3,56	23,1	0,18	0,55	disease	0,88	disease	0,93	disease	0,79	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,48	0,9	1,75	6,71	P	0,69	P	0,9	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6187	6187	C	T	MI.2493	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	284	95	P	L	cCc/cTc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,54	neutral	-2,99	deleterious	-7,56	high_impact	4,57	neutral	0,61	neutral	0,4	deleterious	4,33	24	0,25	0,55	disease	0,8	disease	0,88	disease	0,69	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,12	0,76	0,9	1,75	6,71	P	0,59	P	0,87	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6189	6189	C	T	MI.2494	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	286	96	R	C	Cgc/Tgc	-11,21	0	0	probably_damaging	0,98	deleterious	0	neutral	2,37	deleterious	-6,17	deleterious	-6,14	high_impact	5,26	damaging	0,47	damaging	0,02	deleterious	4,97	25,1	0,27	0,55	disease	0,9	disease	0,84	disease	0,78	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,35	low_impact	-1,48	high_impact	3,76	0,76	0,9	2,14	6,67	P	0,53	P	1	disease_causing	0,97	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6189	6189	C	G	MI.2495	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	286	96	R	G	Cgc/Ggc	-11,21	0	0	possibly_damaging	0,79	deleterious	0	neutral	2,41	deleterious	-3,52	deleterious	-5,37	high_impact	4,71	damaging	0,56	damaging	0,04	deleterious	4,18	23,8	0,24	0,55	disease	0,76	disease	0,71	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,11	deleterious	5	deleterious	0,68	low_impact	-1,3	low_impact	-1,48	high_impact	3,25	0,38	0,9	2,14	6,67	P	0,57	P	0,92	polymorphism	0,92	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6189	6189	C	A	MI.2496	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	286	96	R	S	Cgc/Agc	-11,21	0	0	possibly_damaging	0,73	deleterious	0	neutral	2,44	neutral	-2,7	deleterious	-4,6	high_impact	5,26	damaging	0,54	damaging	0,03	deleterious	4,54	24,3	0,24	0,55	disease	0,62	disease	0,79	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,14	deleterious	5	deleterious	0,68	low_impact	-1,16	low_impact	-1,48	high_impact	3,76	0,42	0,9	2,14	6,67	P	0,59	P	0,8	polymorphism	0,92	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6190	6190	G	A	MI.2497	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	287	96	R	H	cGc/cAc	3,6	0,99	0	benign	0,04	deleterious	0	neutral	2,39	deleterious	-4,29	deleterious	-3,84	high_impact	5,26	damaging	0,55	damaging	0,03	deleterious	4,35	24,1	0,42	0,55	disease	0,75	disease	0,78	disease	0,71	disease	0,74	5	deleterious	1	deleterious	0,48	deleterious	2	neutral	0,29	medium_impact	0,54	low_impact	-1,48	high_impact	3,76	0,8	0,9	2,14	6,67	P	0,62	P	0,98	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6190	6190	G	T	MI.2498	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	287	96	R	L	cGc/cTc	3,6	0,99	0	possibly_damaging	0,63	deleterious	0	neutral	2,41	deleterious	-3,48	deleterious	-5,37	high_impact	4,92	damaging	0,6	damaging	0,02	deleterious	4,29	24	0,23	0,55	disease	0,63	disease	0,87	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,19	deleterious	5	deleterious	0,63	medium_impact	-0,97	low_impact	-1,48	high_impact	3,44	0,3	0,9	2,14	6,67	P	0,66	P	0,99	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6190	6190	G	C	MI.2499	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	287	96	R	P	cGc/cCc	3,6	0,99	0	probably_damaging	0,92	deleterious	0	neutral	2,39	deleterious	-4,14	deleterious	-5,37	high_impact	5,26	damaging	0,4	damaging	0,04	deleterious	4,22	23,9	0,2	0,55	disease	0,81	disease	0,84	disease	0,74	disease	0,8	6	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,82	low_impact	-1,76	low_impact	-1,48	high_impact	3,76	0,34	0,9	2,14	6,67	P	0,71	P	0,99	disease_causing	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8537	8537	A	T	MI.25	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	11	4	N	I	aAt/aTt	5,91	1	0,01	benign	0,38	deleterious	0	neutral	4,42	neutral	-2,07	deleterious	-6,2	medium_impact	2,85	neutral	0,85	neutral	0,48	deleterious	3,59	23,2	0,42	0,65	disease	0,53	disease	0,62	disease	0,58	disease	0,7	4	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,48	medium_impact	-0,55	low_impact	-1,4	medium_impact	1,35	0,37	0,9	41,59	7,51	P	0,64	P	0,97	disease_causing	0,99	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8643	8643	C	G	MI.250	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	117	39	N	K	aaC/aaG	-1,49	0	0	probably_damaging	0,99	neutral	0,23	neutral	4,38	neutral	-0,2	deleterious	-3,77	low_impact	1,12	neutral	0,87	neutral	0,58	deleterious	3,7	23,3	0,83	0,85	neutral	0,38	disease	0,59	neutral	0,27	neutral	0,45	1	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,73	low_impact	-2,65	medium_impact	-0,01	medium_impact	-0,14	0,4	0,9	18,58	19,57	N	0,36	N	0,73	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6192	6192	A	T	MI.2500	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	289	97	M	L	Ata/Tta	-0,57	0,04	0	benign	0	neutral	0,57	neutral	3,33	neutral	2,72	neutral	-1,37	neutral_impact	0,28	damaging	0,57	neutral	0,81	neutral	-0,07	1,98	0,35	0,55	neutral	0,35	neutral	0,39	neutral	0,28	neutral	0,45	1	neutral	0,43	deleterious	0,79	neutral	-6	neutral	0,16	high_impact	2,07	medium_impact	0,26	medium_impact	-0,84	0,73	0,9	12,67	45,68	N	0,45	N	0,01	disease_causing	0,88	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6192	6192	A	G	MI.2501	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	289	97	M	V	Ata/Gta	-0,57	0,04	0	benign	0,05	deleterious	0,03	neutral	2,82	neutral	0,1	neutral	-2,34	medium_impact	3,09	damaging	0,59	neutral	0,46	deleterious	0,85	9,76	0,42	0,55	neutral	0,29	disease	0,82	disease	0,58	disease	0,67	3	neutral	0,97	deleterious	0,49	deleterious	1	neutral	0,22	medium_impact	0,45	medium_impact	-0,65	medium_impact	1,75	0,74	0,9	12,67	45,68	N	0,42	N	0,48	disease_causing	0,9	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6192	6192	A	C	MI.2502	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	289	97	M	L	Ata/Cta	-0,57	0,04	0	benign	0	neutral	0,57	neutral	3,33	neutral	2,72	neutral	-1,37	neutral_impact	0,28	damaging	0,57	neutral	0,81	neutral	-0,18	1,23	0,35	0,55	neutral	0,35	neutral	0,39	neutral	0,28	neutral	0,45	1	neutral	0,43	deleterious	0,79	neutral	-6	neutral	0,16	high_impact	2,07	medium_impact	0,26	medium_impact	-0,84	0,73	0,9	12,67	45,68	N	0,44	N	0,01	disease_causing	0,88	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6193	6193	T	C	MI.2503	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	290	97	M	T	aTa/aCa	4,06	0,99	0	benign	0,33	deleterious	0	neutral	2,76	neutral	-0,75	deleterious	-3,94	high_impact	4,66	damaging	0,58	neutral	0,5	neutral	1,14	11,45	0,31	0,55	disease	0,55	disease	0,88	disease	0,68	disease	0,76	5	deleterious	1	neutral	0,34	deleterious	2	neutral	0,39	medium_impact	-0,47	low_impact	-1,48	high_impact	3,2	0,55	0,9	12,67	45,68	P	0,57	P	0,15	disease_causing	0,99	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6193	6193	T	A	MI.2504	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	290	97	M	K	aTa/aAa	4,06	0,99	0	benign	0,18	deleterious	0	neutral	2,71	neutral	-2,42	deleterious	-4,19	high_impact	4,66	neutral	0,62	neutral	0,42	deleterious	2,11	16,95	0,13	0,55	disease	0,74	disease	0,93	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,41	deleterious	2	neutral	0,39	medium_impact	-0,14	low_impact	-1,48	high_impact	3,2	0,51	0,9	12,67	45,68	P	0,61	P	0,68	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6194	6194	A	T	MI.2505	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	291	97	M	I	atA/atT	7,53	1	0	benign	0,04	neutral	0,06	neutral	2,84	neutral	0,38	neutral	-2,18	medium_impact	3,16	damaging	0,56	neutral	0,51	neutral	1,38	12,66	0,41	0,55	neutral	0,21	disease	0,87	disease	0,55	disease	0,68	4	neutral	0,94	deleterious	0,51	neutral	-3	neutral	0,22	medium_impact	0,54	medium_impact	-0,47	medium_impact	1,82	0,84	0,9	12,67	45,68	P	0,59	P	0,33	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6194	6194	A	C	MI.2506	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	291	97	M	I	atA/atC	7,53	1	0	benign	0,04	neutral	0,06	neutral	2,84	neutral	0,38	neutral	-2,18	medium_impact	3,16	damaging	0,56	neutral	0,51	neutral	1,3	12,27	0,41	0,55	neutral	0,21	disease	0,87	disease	0,55	disease	0,68	4	neutral	0,94	deleterious	0,51	neutral	-3	neutral	0,22	medium_impact	0,54	medium_impact	-0,47	medium_impact	1,82	0,84	0,9	12,67	45,68	P	0,58	P	0,33	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6195	6195	A	C	MI.2507	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	292	98	N	H	Aac/Cac	2,67	1	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-4,17	deleterious	-3,87	high_impact	5,27	damaging	0,57	damaging	0,04	deleterious	3,01	22,3	0,3	0,55	disease	0,89	disease	0,72	disease	0,81	disease	0,83	7	deleterious	1	deleterious	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,77	0,48	0,9	2,73	6,71	P	0,66	P	0,83	disease_causing	0,99	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6195	6195	A	T	MI.2508	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	292	98	N	Y	Aac/Tac	2,67	1	0	probably_damaging	1	deleterious	0	neutral	2,65	deleterious	-4,69	deleterious	-6,19	high_impact	5,27	damaging	0,54	damaging	0,05	deleterious	3,61	23,2	0,25	0,55	disease	0,91	disease	0,76	disease	0,76	disease	0,82	6	deleterious	1	deleterious	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,77	0,49	0,9	2,73	6,71	P	0,58	P	0,93	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6195	6195	A	G	MI.2509	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	292	98	N	D	Aac/Gac	2,67	1	0	probably_damaging	1	deleterious	0	neutral	2,64	deleterious	-3,27	deleterious	-3,87	high_impact	5,27	damaging	0,47	damaging	0,06	deleterious	3,77	23,4	0,44	0,55	disease	0,76	disease	0,63	disease	0,74	disease	0,75	5	deleterious	1	deleterious	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,77	0,62	0,9	2,73	6,71	P	0,66	P	0,92	disease_causing	0,98	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8643	8643	C	A	MI.251	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	117	39	N	K	aaC/aaA	-1,49	0	0	probably_damaging	0,99	neutral	0,23	neutral	4,38	neutral	-0,2	deleterious	-3,77	low_impact	1,12	neutral	0,87	neutral	0,58	deleterious	4,18	23,8	0,83	0,85	neutral	0,38	disease	0,59	neutral	0,27	neutral	0,45	1	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,73	low_impact	-2,65	medium_impact	-0,01	medium_impact	-0,14	0,4	0,9	18,58	19,57	N	0,36	N	0,73	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6196	6196	A	G	MI.2510	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	293	98	N	S	aAc/aGc	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,68	neutral	-2,32	deleterious	-3,87	high_impact	4,92	damaging	0,58	damaging	0,06	deleterious	2,94	22	0,43	0,55	disease	0,59	disease	0,67	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	3,44	0,44	0,9	2,73	6,71	P	0,73	P	0,79	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6196	6196	A	T	MI.2511	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	293	98	N	I	aAc/aTc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-3,71	deleterious	-6,96	high_impact	4,12	damaging	0,59	damaging	0,05	deleterious	3,76	23,3	0,25	0,55	disease	0,61	disease	0,87	disease	0,67	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,44	0,9	2,73	6,71	N	0,5	N	0,98	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6196	6196	A	C	MI.2512	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	293	98	N	T	aAc/aCc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-2,86	deleterious	-4,64	high_impact	5,27	damaging	0,56	damaging	0,07	deleterious	3,32	22,9	0,33	0,55	disease	0,76	disease	0,75	disease	0,74	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,77	0,6	0,9	2,73	6,71	P	0,72	P	0,59	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6197	6197	C	A	MI.2513	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	294	98	N	K	aaC/aaA	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,65	neutral	-2,28	deleterious	-4,64	high_impact	4,92	damaging	0,54	damaging	0,04	deleterious	4,36	24,1	0,4	0,55	disease	0,76	disease	0,78	disease	0,81	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,63	0,9	2,73	6,71	P	0,74	P	0,92	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6197	6197	C	G	MI.2514	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	294	98	N	K	aaC/aaG	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,65	neutral	-2,28	deleterious	-4,64	high_impact	4,92	damaging	0,54	damaging	0,04	deleterious	3,9	23,5	0,4	0,55	disease	0,76	disease	0,78	disease	0,81	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,63	0,9	2,73	6,71	P	0,74	P	0,92	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6198	6198	A	T	MI.2515	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	295	99	N	Y	Aac/Tac	-8,66	0	0	possibly_damaging	0,87	deleterious	0	neutral	2,74	neutral	-2,51	deleterious	-6,21	high_impact	4,82	neutral	0,62	damaging	0,05	deleterious	3,42	23	0,32	0,55	disease	0,67	disease	0,73	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,74	low_impact	-1,53	low_impact	-1,48	high_impact	3,35	0,56	0,9	1,75	6,66	P	0,58	P	0,93	disease_causing	0,98	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6198	6198	A	C	MI.2516	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	295	99	N	H	Aac/Cac	-8,66	0	0	possibly_damaging	0,86	deleterious	0	neutral	2,71	deleterious	-3,94	deleterious	-3,88	high_impact	5,17	neutral	0,61	damaging	0,05	deleterious	2,88	21,8	0,42	0,55	disease	0,64	disease	0,7	disease	0,8	disease	0,77	5	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,72	low_impact	-1,5	low_impact	-1,48	high_impact	3,68	0,64	0,9	1,75	6,66	P	0,64	P	0,83	disease_causing	0,93	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6198	6198	A	G	MI.2517	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	295	99	N	D	Aac/Gac	-8,66	0	0	benign	0,18	deleterious	0	neutral	2,7	deleterious	-4,1	deleterious	-3,88	high_impact	5,17	damaging	0,52	damaging	0,06	deleterious	3,62	23,2	0,55	0,6	disease	0,51	disease	0,59	disease	0,79	disease	0,76	5	deleterious	1	neutral	0,41	deleterious	2	neutral	0,3	medium_impact	-0,14	low_impact	-1,48	high_impact	3,68	0,71	0,9	1,75	6,66	P	0,57	P	0,92	disease_causing	0,86	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6199	6199	A	C	MI.2518	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	296	99	N	T	aAc/aCc	8,69	1	0	benign	0,01	neutral	0,05	neutral	2,74	neutral	-2,54	deleterious	-4,66	high_impact	4,82	neutral	0,63	damaging	0,07	deleterious	3,3	22,9	0,45	0,55	neutral	0,37	disease	0,73	disease	0,73	disease	0,72	4	neutral	0,95	deleterious	0,52	neutral	-2	neutral	0,22	medium_impact	1,12	medium_impact	-0,52	high_impact	3,35	0,64	0,9	1,75	6,66	P	0,66	P	0,59	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6199	6199	A	G	MI.2519	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	296	99	N	S	aAc/aGc	8,69	1	0	benign	0,06	deleterious	0,04	neutral	2,77	neutral	-2,01	deleterious	-3,88	high_impact	3,64	neutral	0,62	damaging	0,06	deleterious	3,01	22,3	0,55	0,6	neutral	0,27	disease	0,64	disease	0,73	disease	0,7	4	neutral	0,96	deleterious	0,49	deleterious	2	neutral	0,23	medium_impact	0,37	medium_impact	-0,58	high_impact	2,26	0,47	0,9	1,75	6,66	P	0,59	P	0,79	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8644	8644	A	G	MI.252	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	118	40	N	D	Aac/Gac	-5,66	0	0	probably_damaging	0,99	deleterious	0,03	neutral	4,3	neutral	-1,53	deleterious	-4,31	medium_impact	2,94	neutral	0,9	neutral	0,53	deleterious	3,55	23,1	0,83	0,85	disease	0,69	disease	0,7	neutral	0,49	neutral	0,49	0	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-2,65	medium_impact	-0,56	medium_impact	1,42	0,74	0,9	48,67	8,5	N	0,45	N	0,97	polymorphism	0,96	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6199	6199	A	T	MI.2520	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	296	99	N	I	aAc/aTc	8,69	1	0	possibly_damaging	0,64	deleterious	0	neutral	2,76	neutral	-2,19	deleterious	-6,99	high_impact	5,17	neutral	0,63	damaging	0,05	deleterious	3,92	23,5	0,33	0,55	disease	0,53	disease	0,85	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,18	deleterious	5	deleterious	0,63	medium_impact	-0,99	low_impact	-1,48	high_impact	3,68	0,42	0,9	1,75	6,66	P	0,65	P	0,98	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6200	6200	C	A	MI.2521	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	297	99	N	K	aaC/aaA	8,69	1	0	benign	0,39	deleterious	0	neutral	2,76	neutral	-2,21	deleterious	-4,66	high_impact	4,82	damaging	0,59	damaging	0,04	deleterious	4,41	24,1	0,59	0,65	neutral	0,39	disease	0,74	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,57	medium_impact	-0,57	low_impact	-1,48	high_impact	3,35	0,77	0,9	1,75	6,66	P	0,65	P	0,92	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6200	6200	C	G	MI.2522	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	297	99	N	K	aaC/aaG	8,69	1	0	benign	0,39	deleterious	0	neutral	2,76	neutral	-2,21	deleterious	-4,66	high_impact	4,82	damaging	0,59	damaging	0,04	deleterious	3,88	23,5	0,59	0,65	neutral	0,39	disease	0,74	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,57	medium_impact	-0,57	low_impact	-1,48	high_impact	3,35	0,77	0,9	1,75	6,66	P	0,65	P	0,92	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6201	6201	A	C	MI.2523	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	298	100	M	L	Ata/Cta	-4,04	0	0	probably_damaging	0,91	neutral	0,33	neutral	3,09	neutral	2,19	neutral	-1,38	neutral_impact	0,74	damaging	0,54	damaging	0,05	deleterious	1,87	15,38	0,4	0,55	neutral	0,24	disease	0,59	neutral	0,48	neutral	0,44	1	neutral	0,92	neutral	0,21	neutral	-2	deleterious	0,6	low_impact	-1,7	medium_impact	0,02	medium_impact	-0,42	0,59	0,9	2,92	6,72	N	0,25	N	0,61	disease_causing	0,8	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6201	6201	A	G	MI.2524	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	298	100	M	V	Ata/Gta	-4,04	0	0	probably_damaging	0,94	deleterious	0	neutral	2,93	neutral	1,01	neutral	-2,43	medium_impact	3,19	damaging	0,59	damaging	0,1	deleterious	2,52	19,6	0,44	0,55	neutral	0,22	disease	0,75	disease	0,55	disease	0,53	1	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,66	low_impact	-1,88	low_impact	-1,48	medium_impact	1,85	0,66	0,9	2,92	6,72	N	0,28	N	0,88	disease_causing	0,83	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6201	6201	A	T	MI.2525	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	298	100	M	L	Ata/Tta	-4,04	0	0	probably_damaging	0,91	neutral	0,33	neutral	3,09	neutral	2,19	neutral	-1,38	neutral_impact	0,74	damaging	0,54	damaging	0,05	deleterious	1,94	15,84	0,4	0,55	neutral	0,24	disease	0,59	neutral	0,48	neutral	0,44	1	neutral	0,92	neutral	0,21	neutral	-2	deleterious	0,6	low_impact	-1,7	medium_impact	0,02	medium_impact	-0,42	0,59	0,9	2,92	6,72	N	0,25	N	0,61	disease_causing	0,8	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6202	6202	T	C	MI.2526	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	299	100	M	T	aTa/aCa	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,83	neutral	-0,11	deleterious	-4,02	high_impact	4,7	neutral	0,66	damaging	0,1	deleterious	2,9	21,8	0,32	0,55	neutral	0,33	disease	0,83	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	high_impact	3,24	0,38	0,9	2,92	6,72	P	0,57	P	0,79	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6202	6202	T	A	MI.2527	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	299	100	M	K	aTa/aAa	8,69	1	0	probably_damaging	0,98	deleterious	0	neutral	2,78	neutral	-1,68	deleterious	-4,25	high_impact	4,7	damaging	0,59	damaging	0,07	deleterious	3,92	23,5	0,17	0,55	disease	0,52	disease	0,89	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,35	low_impact	-1,48	high_impact	3,24	0,48	0,9	2,92	6,72	P	0,71	P	0,93	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6203	6203	A	C	MI.2528	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	300	100	M	I	atA/atC	4,75	1	0	probably_damaging	0,96	neutral	0,13	neutral	2,94	neutral	1,73	neutral	-2,23	medium_impact	2,08	damaging	0,53	damaging	0,09	deleterious	3,2	22,7	0,38	0,55	neutral	0,2	disease	0,61	neutral	0,47	neutral	0,43	1	deleterious	0,98	neutral	0,09	deleterious	1	deleterious	0,67	low_impact	-2,06	medium_impact	-0,27	medium_impact	0,82	0,65	0,9	2,92	6,72	P	0,5	N	0,87	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6203	6203	A	T	MI.2529	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	300	100	M	I	atA/atT	4,75	1	0	probably_damaging	0,96	neutral	0,13	neutral	2,94	neutral	1,73	neutral	-2,23	medium_impact	2,08	damaging	0,53	damaging	0,09	deleterious	3,28	22,8	0,38	0,55	neutral	0,2	disease	0,61	neutral	0,47	neutral	0,43	1	deleterious	0,98	neutral	0,09	deleterious	1	deleterious	0,67	low_impact	-2,06	medium_impact	-0,27	medium_impact	0,82	0,65	0,9	2,92	6,72	P	0,5	N	0,87	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8644	8644	A	C	MI.253	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	118	40	N	H	Aac/Cac	-5,66	0	0	probably_damaging	1	deleterious	0,02	neutral	4,27	neutral	-2,58	deleterious	-4,36	medium_impact	3,29	neutral	0,8	neutral	0,31	deleterious	2,81	21,4	0,72	0,75	disease	0,84	disease	0,77	disease	0,63	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,6	medium_impact	-0,66	medium_impact	1,72	0,56	0,9	48,67	8,5	N	0,28	N	0,98	polymorphism	0,91	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6204	6204	A	C	MI.2530	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	301	101	S	R	Agc/Cgc	-1,03	0	0	probably_damaging	1	deleterious	0,02	neutral	2,66	deleterious	-3,3	deleterious	-3,82	high_impact	4,89	damaging	0,53	damaging	0,04	deleterious	3,72	23,3	0,18	0,55	disease	0,86	disease	0,83	disease	0,81	disease	0,85	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,58	medium_impact	-0,75	high_impact	3,42	0,7	0,9	2,14	6,64	P	0,69	P	0,98	disease_causing	0,94	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6204	6204	A	T	MI.2531	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	301	101	S	C	Agc/Tgc	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	2,64	deleterious	-5,33	deleterious	-3,83	high_impact	5,24	damaging	0,49	damaging	0,04	deleterious	3,27	22,8	0,22	0,55	disease	0,87	disease	0,71	disease	0,71	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,68	0,9	2,14	6,64	P	0,61	P	0,85	disease_causing	0,93	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6204	6204	A	G	MI.2532	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	301	101	S	G	Agc/Ggc	-1,03	0	0	probably_damaging	0,99	deleterious	0	neutral	2,76	neutral	-2,19	deleterious	-2,9	high_impact	3,88	damaging	0,51	damaging	0,1	deleterious	3,44	23	0,31	0,55	neutral	0,3	neutral	0,49	disease	0,67	disease	0,56	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,69	low_impact	-2,64	low_impact	-1,48	high_impact	2,48	0,74	0,9	2,14	6,64	N	0,39	N	0,7	disease_causing	0,76	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6205	6205	G	C	MI.2533	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	302	101	S	T	aGc/aCc	6,84	1	0	probably_damaging	0,97	deleterious	0	neutral	2,71	neutral	-2,84	neutral	-2,3	high_impact	4,54	damaging	0,51	damaging	0,08	deleterious	3,27	22,8	0,3	0,55	neutral	0,3	disease	0,61	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,69	low_impact	-2,18	low_impact	-1,48	high_impact	3,09	0,81	0,9	2,14	6,64	P	0,51	P	0,43	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6205	6205	G	A	MI.2534	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	302	101	S	N	aGc/aAc	6,84	1	0	probably_damaging	0,97	deleterious	0	neutral	2,67	deleterious	-3,19	neutral	-2,3	high_impact	5,24	damaging	0,48	damaging	0,07	deleterious	3,52	23,1	0,49	0,55	disease	0,81	disease	0,67	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,78	low_impact	-2,18	low_impact	-1,48	high_impact	3,74	0,6	0,9	2,14	6,64	P	0,74	P	0,66	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6205	6205	G	T	MI.2535	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	302	101	S	I	aGc/aTc	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,69	deleterious	-3,41	deleterious	-4,61	high_impact	5,24	damaging	0,53	damaging	0,07	deleterious	3,98	23,6	0,2	0,55	disease	0,88	disease	0,87	disease	0,73	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,83	0,9	2,14	6,64	P	0,73	P	0,96	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6207	6207	T	G	MI.2536	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	304	102	F	V	Ttc/Gtc	-0,8	0,05	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-3,34	deleterious	-5,49	high_impact	4,28	neutral	0,72	damaging	0,06	deleterious	4,06	23,7	0,27	0,55	neutral	0,46	disease	0,78	disease	0,77	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	high_impact	2,85	0,65	0,9	5,46	8,29	N	0,45	N	0,84	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6207	6207	T	A	MI.2537	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	304	102	F	I	Ttc/Atc	-0,8	0,05	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-3,68	deleterious	-4,71	high_impact	4,02	neutral	0,74	damaging	0,07	deleterious	4,35	24,1	0,23	0,55	disease	0,58	disease	0,8	disease	0,76	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,61	0,74	0,9	5,46	8,29	N	0,42	N	0,88	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6207	6207	T	C	MI.2538	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	304	102	F	L	Ttc/Ctc	-0,8	0,05	0	probably_damaging	1	deleterious	0	neutral	2,61	neutral	-2,39	deleterious	-4,7	medium_impact	3,31	neutral	0,75	damaging	0,05	deleterious	3,97	23,6	0,44	0,55	neutral	0,41	disease	0,7	disease	0,68	disease	0,62	2	deleterious	1	neutral	0	deleterious	5	deleterious	0,72	low_impact	-3,58	low_impact	-1,48	medium_impact	1,96	0,75	0,9	5,46	8,29	N	0,34	N	0,83	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6208	6208	T	A	MI.2539	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	305	102	F	Y	tTc/tAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,53	neutral	-1,6	neutral	-2,35	medium_impact	3,1	neutral	0,73	damaging	0,06	deleterious	4,14	23,8	0,26	0,55	neutral	0,37	disease	0,67	disease	0,67	disease	0,67	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,71	low_impact	-3,58	low_impact	-1,48	medium_impact	1,76	0,8	0,9	5,46	8,29	P	0,54	P	0,59	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8644	8644	A	T	MI.254	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	118	40	N	Y	Aac/Tac	-5,66	0	0	probably_damaging	1	deleterious	0	neutral	4,27	deleterious	-3,24	deleterious	-6,8	medium_impact	3,48	neutral	0,83	neutral	0,44	deleterious	3,36	22,9	0,35	0,65	disease	0,9	disease	0,84	disease	0,69	disease	0,78	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,86	low_impact	-3,6	low_impact	-1,4	medium_impact	1,89	0,52	0,9	48,67	8,5	N	0,32	N	1	polymorphism	0,72	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6208	6208	T	G	MI.2540	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	305	102	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-6,02	deleterious	-6,28	high_impact	5,17	neutral	0,74	damaging	0,05	deleterious	4,02	23,6	0,25	0,55	disease	0,84	disease	0,79	disease	0,76	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,46	0,9	5,46	8,29	P	0,65	P	0,91	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6208	6208	T	C	MI.2541	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	305	102	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,47	deleterious	-4,63	deleterious	-6,28	high_impact	4,37	neutral	0,75	damaging	0,08	deleterious	4,13	23,8	0,24	0,55	disease	0,7	disease	0,78	disease	0,74	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,94	0,57	0,9	5,46	8,29	P	0,54	P	0,84	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6209	6209	C	G	MI.2542	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	306	102	F	L	ttC/ttG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,61	neutral	-2,39	deleterious	-4,7	medium_impact	3,31	neutral	0,75	damaging	0,05	deleterious	4,28	24	0,44	0,55	neutral	0,41	disease	0,7	disease	0,68	disease	0,62	2	deleterious	1	neutral	0	deleterious	5	deleterious	0,72	low_impact	-3,58	low_impact	-1,48	medium_impact	1,96	0,75	0,9	5,46	8,29	P	0,54	P	0,83	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6209	6209	C	A	MI.2543	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	306	102	F	L	ttC/ttA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,61	neutral	-2,39	deleterious	-4,7	medium_impact	3,31	neutral	0,75	damaging	0,05	deleterious	4,53	24,3	0,44	0,55	neutral	0,41	disease	0,7	disease	0,68	disease	0,62	2	deleterious	1	neutral	0	deleterious	5	deleterious	0,72	low_impact	-3,58	low_impact	-1,48	medium_impact	1,96	0,75	0,9	5,46	8,29	P	0,54	P	0,83	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6210	6210	T	G	MI.2544	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	307	103	W	G	Tga/Gga	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-3,89	deleterious	-10,34	high_impact	4,57	neutral	0,64	damaging	0,12	deleterious	3,81	23,4	0,17	0,55	disease	0,92	disease	0,69	disease	0,79	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,12	0,29	0,9	2,92	6,69	N	0,48	N	0,89	disease_causing	0,99	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6210	6210	T	C	MI.2545	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	307	103	W	R	Tga/Cga	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-4,68	deleterious	-11,14	high_impact	4,57	neutral	0,65	damaging	0,1	deleterious	3,49	23,1	0,22	0,55	disease	0,91	disease	0,84	disease	0,83	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,12	0,31	0,9	2,92	6,69	N	0,51	P	0,98	disease_causing	0,97	0,5	.	.	.	.	.	head/neck tumor	.	.	.	.	.	.	.	.	.
chrM	6211	6211	G	C	MI.2546	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	308	103	W	S	tGa/tCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-3,88	deleterious	-11,13	high_impact	5,26	neutral	0,72	damaging	0,14	deleterious	3,93	23,5	0,16	0,55	disease	0,86	disease	0,8	disease	0,77	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,28	0,9	2,92	6,69	P	0,64	P	0,89	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6211	6211	G	T	MI.2547	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	308	103	W	L	tGa/tTa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,57	neutral	-2,66	deleterious	-10,34	high_impact	3,73	damaging	0,58	damaging	0,12	deleterious	4,14	23,8	0,15	0,55	disease	0,57	disease	0,74	disease	0,77	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,35	0,28	0,9	2,92	6,69	P	0,55	P	0,95	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6212	6212	A	C	MI.2548	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	309	103	W	C	tgA/tgC	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-5,34	deleterious	-10,34	high_impact	5,26	neutral	0,64	damaging	0,1	deleterious	3,89	23,5	0,19	0,55	disease	0,94	disease	0,8	disease	0,82	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,31	0,9	2,92	6,69	P	0,62	P	0,88	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6212	6212	A	T	MI.2549	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	309	103	W	C	tgA/tgT	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-5,34	deleterious	-10,34	high_impact	5,26	neutral	0,64	damaging	0,1	deleterious	4,02	23,6	0,19	0,55	disease	0,94	disease	0,8	disease	0,82	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,31	0,9	2,92	6,69	P	0,62	P	0,88	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8645	8645	A	G	MI.255	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	119	40	N	S	aAc/aGc	5,68	1	0	probably_damaging	0,99	neutral	0,85	neutral	4,45	neutral	-0,66	deleterious	-4,11	neutral_impact	0,57	neutral	0,86	neutral	0,53	deleterious	2,38	18,69	0,82	0,85	neutral	0,37	neutral	0,48	neutral	0,4	neutral	0,42	2	deleterious	0,99	neutral	0,43	neutral	-2	deleterious	0,73	low_impact	-2,65	medium_impact	0,72	medium_impact	-0,61	0,46	0,9	48,67	8,5	N	0,4	N	0,88	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6213	6213	C	G	MI.2550	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	310	104	L	V	Ctc/Gtc	1,98	1	0	possibly_damaging	0,5	neutral	0,07	neutral	2,57	neutral	-1,23	neutral	-2,25	high_impact	3,7	damaging	0,55	damaging	0,15	deleterious	3	22,2	0,37	0,55	neutral	0,3	neutral	0,41	disease	0,51	neutral	0,4	2	neutral	0,92	neutral	0,29	deleterious	1	neutral	0,4	medium_impact	-0,76	medium_impact	-0,43	high_impact	2,32	0,82	0,9	1,56	7,16	P	0,54	P	0,66	disease_causing	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6213	6213	C	T	MI.2551	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	310	104	L	F	Ctc/Ttc	1,98	1	0	possibly_damaging	0,85	deleterious	0,03	neutral	2,44	neutral	-2,83	deleterious	-2,66	medium_impact	2,4	damaging	0,52	damaging	0,11	deleterious	3,83	23,4	0,34	0,55	disease	0,59	neutral	0,46	disease	0,51	disease	0,56	1	deleterious	0,98	neutral	0,09	deleterious	4	deleterious	0,69	low_impact	-1,47	medium_impact	-0,65	medium_impact	1,12	0,72	0,9	1,56	7,16	P	0,49	N	0,87	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6213	6213	C	A	MI.2552	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	310	104	L	I	Ctc/Atc	1,98	1	0	possibly_damaging	0,82	deleterious	0,03	neutral	2,55	neutral	-1,4	neutral	-1,47	high_impact	3,62	damaging	0,55	damaging	0,14	deleterious	3,83	23,4	0,29	0,55	neutral	0,38	disease	0,51	neutral	0,48	neutral	0,46	1	deleterious	0,98	neutral	0,11	deleterious	5	deleterious	0,53	low_impact	-1,38	medium_impact	-0,65	high_impact	2,24	0,77	0,9	1,56	7,16	P	0,51	P	0,54	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6214	6214	T	G	MI.2553	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	311	104	L	R	cTc/cGc	1,52	1	0	possibly_damaging	0,74	deleterious	0	neutral	2,39	deleterious	-4,53	deleterious	-4,59	high_impact	5,14	damaging	0,53	damaging	0,11	deleterious	3,97	23,6	0,12	0,55	disease	0,73	disease	0,79	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,82	low_impact	-1,18	low_impact	-1,48	high_impact	3,65	0,53	0,9	1,56	7,16	P	0,62	P	0,9	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6214	6214	T	A	MI.2554	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	311	104	L	H	cTc/cAc	1,52	1	0	benign	0,08	deleterious	0	neutral	2,39	deleterious	-5,06	deleterious	-5,24	high_impact	5,14	damaging	0,59	damaging	0,1	deleterious	2,33	18,38	0,12	0,55	disease	0,79	disease	0,73	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,46	deleterious	2	neutral	0,31	medium_impact	0,24	low_impact	-1,48	high_impact	3,65	0,54	0,9	1,56	7,16	P	0,56	P	0,83	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6214	6214	T	C	MI.2555	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	311	104	L	P	cTc/cCc	1,52	1	0	probably_damaging	0,98	deleterious	0	neutral	2,39	deleterious	-5,1	deleterious	-5,39	high_impact	5,14	damaging	0,47	damaging	0,12	deleterious	3,83	23,4	0,15	0,55	disease	0,79	disease	0,7	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,35	low_impact	-1,48	high_impact	3,65	0,74	0,9	1,56	7,16	P	0,59	P	0,83	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6216	6216	T	G	MI.2556	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	313	105	L	V	Tta/Gta	-20	0	0,02	probably_damaging	0,99	neutral	0,05	neutral	2,61	neutral	-1,5	neutral	-2,11	medium_impact	3,41	damaging	0,56	damaging	0,13	deleterious	3,31	22,9	0,39	0,55	neutral	0,34	neutral	0,47	neutral	0,47	neutral	0,43	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,69	low_impact	-2,64	medium_impact	-0,52	high_impact	2,05	0,65	0,9	2,34	6,67	N	0,35	N	0,66	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6216	6216	T	A	MI.2557	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	313	105	L	M	Tta/Ata	-20	0	0,02	probably_damaging	1	deleterious	0	neutral	2,6	neutral	-1,67	neutral	-1,52	high_impact	3,52	neutral	0,63	damaging	0,16	deleterious	3,49	23,1	0,33	0,55	disease	0,52	disease	0,51	neutral	0,47	neutral	0,46	1	deleterious	1	neutral	0	deleterious	6	deleterious	0,71	low_impact	-3,58	low_impact	-1,48	high_impact	2,15	0,63	0,9	2,34	6,67	N	0,36	N	0,59	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6217	6217	T	C	MI.2558	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	314	105	L	S	tTa/tCa	1,52	0,76	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-3	deleterious	-4,66	high_impact	4,1	neutral	0,64	damaging	0,13	deleterious	3,65	23,2	0,21	0,55	neutral	0,48	disease	0,67	disease	0,56	disease	0,64	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	2,69	0,73	0,9	2,34	6,67	N	0,31	N	0,73	disease_causing	0,93	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6217	6217	T	G	MI.2559	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	314	105	L	W	tTa/tGa	1,52	0,76	0	probably_damaging	1	deleterious	0	neutral	2,57	neutral	-2,18	deleterious	-4,73	high_impact	4,45	neutral	0,6	damaging	0,13	deleterious	3,68	23,3	0,12	0,55	disease	0,6	disease	0,66	disease	0,6	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	3,01	0,52	0,9	2,34	6,67	N	0,4	N	0,92	disease_causing	0,95	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8645	8645	A	T	MI.256	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	119	40	N	I	aAc/aTc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	4,32	neutral	-2,68	deleterious	-7,58	medium_impact	3,48	neutral	0,82	neutral	0,57	deleterious	4,29	24	0,32	0,65	disease	0,88	disease	0,86	disease	0,65	disease	0,78	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,85	low_impact	-3,6	low_impact	-1,4	medium_impact	1,89	0,42	0,9	48,67	8,5	P	0,55	P	1	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6218	6218	A	C	MI.2560	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	315	105	L	F	ttA/ttC	7,53	0,99	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-0,91	deleterious	-3,07	medium_impact	3,31	damaging	0,54	damaging	0,09	deleterious	3,34	22,9	0,3	0,55	neutral	0,23	disease	0,59	neutral	0,49	neutral	0,49	0	deleterious	1	neutral	0	deleterious	5	deleterious	0,7	low_impact	-3,58	low_impact	-1,48	medium_impact	1,96	0,66	0,9	2,34	6,67	P	0,51	P	0,87	disease_causing	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6218	6218	A	T	MI.2561	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	315	105	L	F	ttA/ttT	7,53	0,99	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-0,91	deleterious	-3,07	medium_impact	3,31	damaging	0,54	damaging	0,09	deleterious	3,47	23	0,3	0,55	neutral	0,23	disease	0,59	neutral	0,49	neutral	0,49	0	deleterious	1	neutral	0	deleterious	5	deleterious	0,7	low_impact	-3,58	low_impact	-1,48	medium_impact	1,96	0,66	0,9	2,34	6,67	P	0,52	P	0,87	disease_causing	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6219	6219	C	T	MI.2562	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	316	106	P	S	Cct/Tct	-20	0	0	benign	0,02	deleterious	0	neutral	2,74	neutral	-1,29	deleterious	-6,14	high_impact	4,38	neutral	0,61	neutral	0,49	deleterious	3,79	23,4	0,3	0,55	disease	0,56	disease	0,66	disease	0,57	disease	0,64	3	deleterious	1	deleterious	0,49	deleterious	2	neutral	0,2	medium_impact	0,83	low_impact	-1,48	high_impact	2,95	0,32	0,9	2,73	7,05	N	0,47	N	0,85	polymorphism	0,9	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6219	6219	C	A	MI.2563	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	316	106	P	T	Cct/Act	-20	0	0	benign	0,26	deleterious	0	neutral	2,77	neutral	-0,66	deleterious	-6,1	high_impact	4,1	damaging	0,6	neutral	0,37	deleterious	3,62	23,2	0,22	0,55	disease	0,5	disease	0,64	disease	0,58	disease	0,64	3	deleterious	1	neutral	0,37	deleterious	2	neutral	0,34	medium_impact	-0,33	low_impact	-1,48	high_impact	2,69	0,48	0,9	2,73	7,05	N	0,4	N	0,8	polymorphism	0,9	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6219	6219	C	G	MI.2564	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	316	106	P	A	Cct/Gct	-20	0	0	benign	0,04	deleterious	0	neutral	2,84	neutral	0,37	deleterious	-6,1	high_impact	4,04	neutral	0,64	neutral	0,48	deleterious	2,96	22,1	0,2	0,55	neutral	0,45	disease	0,51	disease	0,59	disease	0,62	2	deleterious	1	deleterious	0,48	deleterious	2	neutral	0,22	medium_impact	0,54	low_impact	-1,48	high_impact	2,63	0,51	0,9	2,73	7,05	N	0,46	N	0,76	polymorphism	0,93	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6220	6220	C	T	MI.2565	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	317	106	P	L	cCt/cTt	7,3	1	0	possibly_damaging	0,6	deleterious	0,02	neutral	2,94	neutral	1,19	deleterious	-7,56	medium_impact	2,54	damaging	0,49	neutral	0,41	deleterious	4,16	23,8	0,2	0,55	neutral	0,19	disease	0,77	disease	0,55	disease	0,62	2	deleterious	0,98	neutral	0,21	deleterious	4	deleterious	0,53	medium_impact	-0,92	medium_impact	-0,75	medium_impact	1,25	0,75	0,9	2,73	7,05	P	0,5	N	0,87	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6220	6220	C	G	MI.2566	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	317	106	P	R	cCt/cGt	7,3	1	0	possibly_damaging	0,82	deleterious	0	neutral	2,72	neutral	-2,16	deleterious	-6,94	high_impact	5,08	damaging	0,59	neutral	0,35	deleterious	3,45	23	0,17	0,55	disease	0,68	disease	0,81	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,09	deleterious	5	deleterious	0,7	low_impact	-1,38	low_impact	-1,48	high_impact	3,59	0,5	0,9	2,73	7,05	P	0,68	P	0,9	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6220	6220	C	A	MI.2567	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	317	106	P	H	cCt/cAt	7,3	1	0	possibly_damaging	0,89	deleterious	0	neutral	2,73	neutral	-2,05	deleterious	-6,95	high_impact	5,08	damaging	0,59	neutral	0,34	deleterious	3,94	23,5	0,21	0,55	disease	0,75	disease	0,78	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,73	low_impact	-1,61	low_impact	-1,48	high_impact	3,59	0,36	0,9	2,73	7,05	P	0,69	P	0,81	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6222	6222	C	G	MI.2568	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	319	107	P	A	Ccc/Gcc	-9,36	0	0	probably_damaging	1	deleterious	0,04	neutral	2,91	neutral	1,19	deleterious	-6,42	high_impact	3,72	neutral	0,66	damaging	0,06	deleterious	3,02	22,3	0,24	0,55	neutral	0,23	neutral	0,5	neutral	0,41	neutral	0,43	1	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,68	low_impact	-3,58	medium_impact	-0,58	high_impact	2,34	0,69	0,9	2,92	6,77	N	0,35	N	0,76	polymorphism	0,93	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6222	6222	C	T	MI.2569	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	319	107	P	S	Ccc/Tcc	-9,36	0	0	probably_damaging	1	deleterious	0,02	neutral	2,79	neutral	-0,35	deleterious	-6,41	medium_impact	3,37	neutral	0,64	damaging	0,03	deleterious	3,82	23,4	0,34	0,55	neutral	0,41	disease	0,7	neutral	0,5	neutral	0,49	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,72	low_impact	-3,58	medium_impact	-0,75	high_impact	2,01	0,47	0,9	2,92	6,77	N	0,29	N	0,85	polymorphism	0,9	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8645	8645	A	C	MI.257	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	119	40	N	T	aAc/aCc	5,68	1	0	probably_damaging	0,99	neutral	0,09	neutral	4,39	neutral	-1,01	deleterious	-5,06	low_impact	1,47	neutral	0,87	neutral	0,55	deleterious	3,7	23,3	0,72	0,75	disease	0,68	disease	0,75	neutral	0,43	disease	0,55	1	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,79	low_impact	-2,65	medium_impact	-0,28	medium_impact	0,16	0,66	0,9	48,67	8,5	N	0,51	P	0,96	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6222	6222	C	A	MI.2570	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	319	107	P	T	Ccc/Acc	-9,36	0	0	probably_damaging	1	neutral	0,07	neutral	2,8	neutral	-0,1	deleterious	-6,42	high_impact	4,56	neutral	0,66	damaging	0,04	deleterious	3,61	23,2	0,25	0,55	neutral	0,32	disease	0,67	disease	0,58	disease	0,58	2	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,7	low_impact	-3,58	medium_impact	-0,43	high_impact	3,11	0,68	0,9	2,92	6,77	N	0,4	N	0,8	polymorphism	0,9	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6223	6223	C	A	MI.2571	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	320	107	P	H	cCc/cAc	4,52	0,99	0	probably_damaging	1	deleterious	0	neutral	2,73	neutral	-2,55	deleterious	-7,22	high_impact	4,3	neutral	0,65	damaging	0,02	deleterious	3,93	23,5	0,21	0,55	disease	0,63	disease	0,81	disease	0,67	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,87	0,52	0,9	2,92	6,77	N	0,47	N	0,81	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6223	6223	C	G	MI.2572	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	320	107	P	R	cCc/cGc	4,52	0,99	0	probably_damaging	1	deleterious	0	neutral	2,74	neutral	-1,98	deleterious	-7,23	high_impact	5,11	neutral	0,62	damaging	0,03	deleterious	3,51	23,1	0,18	0,55	disease	0,55	disease	0,83	disease	0,72	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,65	0,9	2,92	6,77	P	0,66	P	0,9	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6223	6223	C	T	MI.2573	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	320	107	P	L	cCc/cTc	4,52	0,99	0	probably_damaging	1	deleterious	0	neutral	2,97	neutral	1,56	deleterious	-8,02	high_impact	3,87	neutral	0,66	damaging	0,02	deleterious	4,3	24	0,32	0,55	neutral	0,24	disease	0,82	disease	0,55	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,7	low_impact	-3,58	low_impact	-1,48	high_impact	2,47	0,86	0,9	2,92	6,77	N	0,45	N	0,87	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6225	6225	T	C	MI.2574	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	322	108	S	P	Tct/Cct	-11,44	0	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-3,78	deleterious	-3,51	high_impact	3,96	damaging	0,45	damaging	0,06	deleterious	3,86	23,5	0,21	0,55	disease	0,73	disease	0,81	disease	0,71	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,56	0,56	0,9	1,36	6,84	N	0,33	N	0,91	polymorphism	0,98	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6225	6225	T	A	MI.2575	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	322	108	S	T	Tct/Act	-11,44	0	0	probably_damaging	0,97	deleterious	0	neutral	2,68	neutral	-1,63	neutral	-2,07	high_impact	4,58	damaging	0,49	damaging	0,06	deleterious	3,66	23,2	0,28	0,55	neutral	0,19	disease	0,51	disease	0,53	disease	0,53	1	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,66	low_impact	-2,18	low_impact	-1,48	high_impact	3,13	0,66	0,9	1,36	6,84	N	0,44	N	0,43	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6225	6225	T	G	MI.2576	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	322	108	S	A	Tct/Gct	-11,44	0	0	probably_damaging	0,99	neutral	0,29	neutral	3,05	neutral	1,29	neutral	-1,36	low_impact	1,08	damaging	0,48	damaging	0,21	deleterious	2,15	17,18	0,32	0,55	neutral	0,21	neutral	0,18	neutral	0,32	neutral	0,25	5	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,63	low_impact	-2,64	medium_impact	-0,02	medium_impact	-0,1	0,58	0,9	1,36	6,84	N	0,44	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6226	6226	C	G	MI.2577	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	323	108	S	C	tCt/tGt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-4,35	deleterious	-3,33	high_impact	4,93	damaging	0,49	damaging	0,04	deleterious	3,48	23,1	0,2	0,55	disease	0,8	disease	0,7	disease	0,59	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,58	0,9	1,36	6,84	P	0,66	P	0,85	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6226	6226	C	T	MI.2578	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	323	108	S	F	tCt/tTt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-4,26	deleterious	-4,31	high_impact	4,24	damaging	0,49	damaging	0,04	deleterious	4,08	23,7	0,15	0,55	disease	0,86	disease	0,78	disease	0,63	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,82	0,33	0,9	1,36	6,84	N	0,47	N	0,98	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6226	6226	C	A	MI.2579	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	323	108	S	Y	tCt/tAt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-4,54	deleterious	-4,31	high_impact	4,93	damaging	0,5	damaging	0,06	deleterious	3,87	23,5	0,17	0,55	disease	0,88	disease	0,75	disease	0,63	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,55	0,9	1,36	6,84	P	0,67	P	0,92	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8646	8646	C	A	MI.258	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	120	40	N	K	aaC/aaA	5,68	1	0	probably_damaging	0,99	neutral	0,07	neutral	4,34	neutral	-0,62	deleterious	-5,12	medium_impact	2,79	neutral	0,79	neutral	0,4	deleterious	4,26	23,9	0,76	0,8	disease	0,63	disease	0,81	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,83	low_impact	-2,65	medium_impact	-0,34	medium_impact	1,29	0,73	0,9	48,67	8,5	P	0,51	P	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6228	6228	C	A	MI.2580	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	325	109	L	I	Ctc/Atc	-6,58	0	0,01	benign	0,13	neutral	0,05	neutral	2,7	neutral	-0,94	neutral	-0,85	medium_impact	2	neutral	0,71	neutral	0,73	neutral	0,93	10,26	0,32	0,55	neutral	0,2	neutral	0,37	neutral	0,29	neutral	0,44	1	neutral	0,94	neutral	0,46	neutral	-3	neutral	0,16	medium_impact	0,02	medium_impact	-0,52	medium_impact	0,75	0,54	0,9	8,38	33,89	N	0,56	P	0,13	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6228	6228	C	G	MI.2581	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	325	109	L	V	Ctc/Gtc	-6,58	0	0,01	benign	0,13	neutral	0,06	neutral	2,76	neutral	-0,36	neutral	-1,58	high_impact	3,52	neutral	0,68	neutral	0,7	neutral	1,36	12,6	0,37	0,55	neutral	0,31	neutral	0,41	neutral	0,44	neutral	0,45	1	neutral	0,93	neutral	0,47	neutral	-2	neutral	0,17	medium_impact	0,02	medium_impact	-0,47	high_impact	2,15	0,58	0,9	8,38	33,89	N	0,51	P	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6228	6228	C	T	MI.2582	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	325	109	L	F	Ctc/Ttc	-6,58	0	0,01	benign	0	neutral	0,67	neutral	2,64	neutral	-1,99	neutral	-1,38	low_impact	1,32	neutral	0,77	neutral	0,99	deleterious	0,29	5,62	0,36	0,55	neutral	0,27	neutral	0,16	neutral	0,26	neutral	0,23	5	neutral	0,32	deleterious	0,84	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,36	medium_impact	0,12	0,61	0,9	8,38	33,89	N	0,42	N	0	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6229	6229	T	C	MI.2583	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	326	109	L	P	cTc/cCc	3,14	0,99	0	possibly_damaging	0,79	deleterious	0	neutral	2,61	neutral	-2,99	deleterious	-4,85	high_impact	4,29	damaging	0,5	neutral	0,43	deleterious	2	16,2	0,16	0,55	disease	0,7	disease	0,76	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	5	deleterious	0,69	low_impact	-1,3	low_impact	-1,48	high_impact	2,86	0,55	0,9	8,38	33,89	P	0,52	P	0,39	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6229	6229	T	G	MI.2584	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	326	109	L	R	cTc/cGc	3,14	0,99	0	possibly_damaging	0,65	deleterious	0	neutral	2,61	deleterious	-3,3	deleterious	-4,18	high_impact	4,84	damaging	0,56	neutral	0,5	deleterious	2,23	17,7	0,15	0,55	disease	0,61	disease	0,81	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	5	deleterious	0,59	low_impact	-1,01	low_impact	-1,48	high_impact	3,37	0,56	0,9	8,38	33,89	P	0,65	P	0,25	polymorphism	0,83	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6229	6229	T	A	MI.2585	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	326	109	L	H	cTc/cAc	3,14	0,99	0	possibly_damaging	0,79	deleterious	0	neutral	2,6	deleterious	-3,91	deleterious	-4,4	high_impact	4,84	neutral	0,64	neutral	0,52	deleterious	2,22	17,66	0,2	0,55	disease	0,58	disease	0,69	disease	0,55	disease	0,64	3	deleterious	1	neutral	0,11	deleterious	5	deleterious	0,62	low_impact	-1,3	low_impact	-1,48	high_impact	3,37	0,5	0,9	8,38	33,89	P	0,66	P	0,17	polymorphism	0,9	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6231	6231	C	A	MI.2586	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	328	110	L	M	Cta/Ata	-3,34	0	0	probably_damaging	1	neutral	0,1	neutral	2,58	neutral	-2,66	neutral	-0,14	neutral_impact	0,76	neutral	0,7	damaging	0,23	deleterious	2,24	17,77	0,26	0,55	neutral	0,34	neutral	0,12	neutral	0,19	neutral	0,3	4	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,66	low_impact	-3,58	medium_impact	-0,34	medium_impact	-0,4	0,55	0,9	3,12	7,51	N	0,49	N	0,59	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6231	6231	C	G	MI.2587	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	328	110	L	V	Cta/Gta	-3,34	0	0	probably_damaging	0,97	neutral	0,07	neutral	2,84	neutral	0,17	neutral	-0,29	low_impact	1,4	neutral	0,66	damaging	0,12	deleterious	0,58	7,99	0,29	0,55	neutral	0,23	neutral	0,19	neutral	0,21	neutral	0,38	2	deleterious	0,99	neutral	0,05	neutral	-2	deleterious	0,62	low_impact	-2,18	medium_impact	-0,43	medium_impact	0,19	0,37	0,9	3,12	7,51	N	0,42	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6232	6232	T	A	MI.2588	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	329	110	L	Q	cTa/cAa	1,75	0,9	0	probably_damaging	1	deleterious	0,01	neutral	2,56	deleterious	-3,93	neutral	-2,32	high_impact	3,63	neutral	0,65	damaging	0,09	deleterious	2,84	21,6	0,16	0,55	disease	0,69	neutral	0,46	neutral	0,44	disease	0,62	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-3,58	medium_impact	-0,92	high_impact	2,25	0,43	0,9	3,12	7,51	N	0,37	N	0,82	disease_causing	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6232	6232	T	G	MI.2589	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	329	110	L	R	cTa/cGa	1,75	0,9	0	probably_damaging	1	deleterious	0,01	neutral	2,56	deleterious	-3,75	neutral	-2,49	high_impact	3,63	damaging	0,6	damaging	0,08	deleterious	2,98	22,2	0,14	0,55	disease	0,67	disease	0,69	disease	0,59	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,58	medium_impact	-0,92	high_impact	2,25	0,46	0,9	3,12	7,51	N	0,29	N	0,9	disease_causing	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8646	8646	C	G	MI.259	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	120	40	N	K	aaC/aaG	5,68	1	0	probably_damaging	0,99	neutral	0,07	neutral	4,34	neutral	-0,62	deleterious	-5,12	medium_impact	2,79	neutral	0,79	neutral	0,4	deleterious	3,85	23,4	0,76	0,8	disease	0,63	disease	0,81	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,83	low_impact	-2,65	medium_impact	-0,34	medium_impact	1,29	0,73	0,9	48,67	8,5	P	0,49	N	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6232	6232	T	C	MI.2590	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	329	110	L	P	cTa/cCa	1,75	0,9	0	probably_damaging	1	deleterious	0,01	neutral	2,55	deleterious	-4,32	deleterious	-2,85	high_impact	3,63	damaging	0,59	damaging	0,07	deleterious	2,62	20,3	0,14	0,55	disease	0,74	disease	0,73	disease	0,58	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,58	medium_impact	-0,92	high_impact	2,25	0,5	0,9	3,12	7,51	N	0,3	N	0,83	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6234	6234	C	A	MI.2591	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	331	111	L	I	Ctc/Atc	-20	0	0	possibly_damaging	0,63	deleterious	0	neutral	2,49	neutral	-1,29	neutral	-1,5	medium_impact	3,08	damaging	0,49	damaging	0,13	deleterious	4,01	23,6	0,26	0,55	neutral	0,43	disease	0,55	neutral	0,41	neutral	0,47	1	deleterious	1	neutral	0,19	deleterious	4	neutral	0,42	medium_impact	-0,97	low_impact	-1,48	medium_impact	1,75	0,59	0,9	2,73	6,77	N	0,39	N	0,54	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6234	6234	C	G	MI.2592	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	331	111	L	V	Ctc/Gtc	-20	0	0	benign	0,28	deleterious	0	neutral	2,59	neutral	-1,03	neutral	-2,26	high_impact	3,91	damaging	0,46	damaging	0,12	deleterious	3,33	22,9	0,31	0,55	neutral	0,4	neutral	0,46	disease	0,52	neutral	0,46	1	deleterious	1	neutral	0,36	deleterious	2	neutral	0,27	medium_impact	-0,37	low_impact	-1,48	high_impact	2,51	0,47	0,9	2,73	6,77	N	0,41	N	0,66	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6234	6234	C	T	MI.2593	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	331	111	L	F	Ctc/Ttc	-20	0	0	probably_damaging	0,91	neutral	0,07	neutral	2,46	neutral	-2,6	deleterious	-2,78	low_impact	1,86	damaging	0,42	damaging	0,09	deleterious	3,87	23,5	0,26	0,55	neutral	0,4	neutral	0,39	neutral	0,32	neutral	0,42	2	neutral	0,98	neutral	0,08	neutral	-2	deleterious	0,68	low_impact	-1,7	medium_impact	-0,43	medium_impact	0,62	0,4	0,9	2,73	6,77	N	0,36	N	0,87	polymorphism	0,98	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6235	6235	T	A	MI.2594	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	332	111	L	H	cTc/cAc	0,13	0,01	0	probably_damaging	0,95	deleterious	0	neutral	2,37	deleterious	-4,7	deleterious	-5,31	high_impact	4,66	damaging	0,53	damaging	0,09	deleterious	4,22	23,9	0,15	0,55	neutral	0,39	disease	0,74	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,72	low_impact	-1,96	low_impact	-1,48	high_impact	3,2	0,41	0,9	2,73	6,77	N	0,41	N	0,83	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6235	6235	T	C	MI.2595	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	332	111	L	P	cTc/cCc	0,13	0,01	0	benign	0,06	deleterious	0	neutral	2,37	deleterious	-4,86	deleterious	-5,42	high_impact	4,66	damaging	0,42	damaging	0,12	deleterious	3,87	23,5	0,14	0,55	disease	0,8	disease	0,77	disease	0,65	disease	0,73	5	deleterious	1	deleterious	0,47	deleterious	2	neutral	0,31	medium_impact	0,37	low_impact	-1,48	high_impact	3,2	0,37	0,9	2,73	6,77	P	0,5	N	0,83	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6235	6235	T	G	MI.2596	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	332	111	L	R	cTc/cGc	0,13	0,01	0	possibly_damaging	0,9	deleterious	0	neutral	2,38	deleterious	-4,28	deleterious	-4,61	high_impact	5,01	damaging	0,51	damaging	0,1	deleterious	4,1	23,7	0,11	0,55	disease	0,74	disease	0,83	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,81	low_impact	-1,65	low_impact	-1,48	high_impact	3,53	0,38	0,9	2,73	6,77	P	0,62	P	0,9	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6237	6237	C	G	MI.2597	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	334	112	L	V	Ctg/Gtg	-20	0	0	probably_damaging	0,98	neutral	0,1	neutral	2,82	neutral	-0,7	neutral	-2,33	medium_impact	3,04	damaging	0,44	neutral	0,39	deleterious	3,36	22,9	0,34	0,55	neutral	0,22	neutral	0,4	neutral	0,48	neutral	0,39	2	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,67	low_impact	-2,35	medium_impact	-0,34	medium_impact	1,71	0,68	0,9	2,14	6,78	N	0,51	P	0,66	polymorphism	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6237	6237	C	A	MI.2598	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	334	112	L	M	Ctg/Atg	-20	0	0	probably_damaging	1	deleterious	0,03	neutral	2,68	neutral	-1,28	neutral	-1,51	medium_impact	2,42	damaging	0,37	neutral	0,56	deleterious	3,69	23,3	0,25	0,55	neutral	0,45	neutral	0,41	neutral	0,31	neutral	0,42	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,7	low_impact	-3,58	medium_impact	-0,65	medium_impact	1,14	0,58	0,9	2,14	6,78	P	0,62	P	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6238	6238	T	C	MI.2599	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	335	112	L	P	cTg/cCg	0,36	0,02	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-4,44	deleterious	-5,58	high_impact	4,39	damaging	0,4	neutral	0,35	deleterious	3,82	23,4	0,15	0,55	disease	0,88	disease	0,71	disease	0,71	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,95	0,55	0,9	2,14	6,78	P	0,63	P	0,83	disease_causing	0,75	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8537	8537	A	C	MI.26	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	11	4	N	T	aAt/aCt	5,91	1	0,01	benign	0,07	neutral	0,13	neutral	4,47	neutral	-0,91	deleterious	-3,74	medium_impact	2,5	neutral	0,87	neutral	0,62	deleterious	3,28	22,8	0,61	0,7	disease	0,71	neutral	0,33	neutral	0,34	disease	0,64	3	neutral	0,86	deleterious	0,53	neutral	-3	neutral	0,22	medium_impact	0,31	medium_impact	-0,18	medium_impact	1,05	0,38	0,9	41,59	7,51	P	0,73	P	0,75	disease_causing	0,96	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8647	8647	C	T	MI.260	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	121	41	R	W	Cga/Tga	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	4,16	deleterious	-5,77	deleterious	-7,18	high_impact	4	damaging	0,59	neutral	0,28	deleterious	5,03	25,2	0,31	0,65	disease	0,96	disease	0,89	disease	0,79	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,6	low_impact	-1,4	high_impact	2,33	0,77	0,9	44,69	8,36	N	0,37	N	1	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6238	6238	T	A	MI.2600	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	335	112	L	Q	cTg/cAg	0,36	0,02	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-4,01	deleterious	-4,76	high_impact	5,08	damaging	0,49	neutral	0,39	deleterious	4,1	23,7	0,14	0,55	disease	0,85	disease	0,69	disease	0,58	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,59	0,61	0,9	2,14	6,78	P	0,63	P	0,82	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6238	6238	T	G	MI.2601	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	335	112	L	R	cTg/cGg	0,36	0,02	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-3,84	deleterious	-4,78	high_impact	5,08	damaging	0,49	neutral	0,31	deleterious	4,1	23,7	0,12	0,55	disease	0,84	disease	0,78	disease	0,71	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,59	0,5	0,9	2,14	6,78	P	0,66	P	0,9	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6240	6240	C	A	MI.2602	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	337	113	L	I	Ctc/Atc	-16,07	0	0	benign	0	neutral	0,23	neutral	2,65	neutral	-0,95	neutral	-0,32	neutral_impact	0,8	neutral	0,64	neutral	0,63	deleterious	0,65	8,49	0,37	0,55	neutral	0,34	neutral	0,18	neutral	0,22	neutral	0,28	4	neutral	0,77	deleterious	0,62	neutral	-6	neutral	0,13	high_impact	2,07	medium_impact	-0,1	medium_impact	-0,36	0,68	0,9	12,67	32,83	N	0,56	P	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6240	6240	C	T	MI.2603	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	337	113	L	F	Ctc/Ttc	-16,07	0	0	benign	0,18	deleterious	0,02	neutral	2,53	neutral	-2,39	neutral	-1,93	medium_impact	2,68	damaging	0,58	neutral	0,44	deleterious	2,02	16,35	0,36	0,55	disease	0,54	neutral	0,47	neutral	0,31	disease	0,52	0	neutral	0,98	neutral	0,42	deleterious	1	deleterious	0,48	medium_impact	-0,14	medium_impact	-0,75	medium_impact	1,38	0,6	0,9	12,67	32,83	N	0,45	N	0,82	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6240	6240	C	G	MI.2604	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	337	113	L	V	Ctc/Gtc	-16,07	0	0	benign	0,01	deleterious	0,04	neutral	2,67	neutral	-0,81	neutral	-0,88	low_impact	1,87	damaging	0,6	neutral	0,48	deleterious	0,24	5,06	0,37	0,55	neutral	0,2	neutral	0,24	neutral	0,26	neutral	0,43	1	neutral	0,96	deleterious	0,52	neutral	-2	neutral	0,11	medium_impact	1,12	medium_impact	-0,58	medium_impact	0,63	0,56	0,9	12,67	32,83	N	0,56	P	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6241	6241	T	C	MI.2605	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	338	113	L	P	cTc/cCc	-1,03	0	0	possibly_damaging	0,81	deleterious	0	neutral	2,49	deleterious	-4,05	deleterious	-4,44	high_impact	4,59	damaging	0,57	neutral	0,41	deleterious	2,19	17,43	0,14	0,55	disease	0,73	disease	0,8	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,1	deleterious	5	deleterious	0,77	low_impact	-1,35	low_impact	-1,48	high_impact	3,14	0,54	0,9	12,67	32,83	N	0,48	N	0,81	disease_causing	0,54	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6241	6241	T	A	MI.2606	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	338	113	L	H	cTc/cAc	-1,03	0	0	possibly_damaging	0,74	deleterious	0	neutral	2,48	deleterious	-4,34	deleterious	-4,36	high_impact	4,59	neutral	0,61	neutral	0,39	deleterious	3,67	23,2	0,16	0,55	neutral	0,3	disease	0,69	disease	0,59	disease	0,66	3	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,63	low_impact	-1,18	low_impact	-1,48	high_impact	3,14	0,59	0,9	12,67	32,83	N	0,5	N	0,69	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6241	6241	T	G	MI.2607	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	338	113	L	R	cTc/cGc	-1,03	0	0	possibly_damaging	0,49	deleterious	0	neutral	2,48	deleterious	-4,11	deleterious	-4,01	high_impact	4,59	damaging	0,57	neutral	0,34	deleterious	2,3	18,13	0,13	0,55	disease	0,63	disease	0,81	disease	0,64	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	5	deleterious	0,64	medium_impact	-0,74	low_impact	-1,48	high_impact	3,14	0,66	0,9	12,67	32,83	N	0,46	N	0,91	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6243	6243	G	T	MI.2608	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	340	114	A	S	Gca/Tca	-2,65	0	0	possibly_damaging	0,5	neutral	0,48	neutral	2,73	neutral	-0,97	neutral	0,03	neutral_impact	-0,36	neutral	0,67	neutral	0,62	neutral	-0,59	0,13	0,39	0,55	neutral	0,32	neutral	0,11	neutral	0,21	neutral	0,3	4	neutral	0,52	deleterious	0,49	neutral	-3	neutral	0,27	medium_impact	-0,76	medium_impact	0,17	low_impact	-1,43	0,81	0,9	7,02	9,53	N	0,4	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6243	6243	G	A	MI.2609	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	340	114	A	T	Gca/Aca	-2,65	0	0	possibly_damaging	0,7	neutral	0,35	neutral	2,72	neutral	-1,22	neutral	-0,42	low_impact	1	neutral	0,71	neutral	0,68	deleterious	0,55	7,77	0,34	0,55	neutral	0,29	neutral	0,15	neutral	0,23	neutral	0,3	4	neutral	0,74	neutral	0,33	neutral	-3	deleterious	0,52	low_impact	-1,1	medium_impact	0,04	medium_impact	-0,18	0,7	0,9	7,02	9,53	N	0,46	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8647	8647	C	G	MI.261	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	121	41	R	G	Cga/Gga	-2,42	0	0	probably_damaging	0,99	deleterious	0,01	neutral	4,32	neutral	-0,57	deleterious	-6,32	medium_impact	3,03	damaging	0,6	neutral	0,45	deleterious	4,06	23,7	0,24	0,65	disease	0,52	disease	0,78	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-2,65	medium_impact	-0,84	medium_impact	1,5	0,43	0,9	44,69	8,36	N	0,37	N	1	disease_causing	1	0,1	rs1064597	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6243	6243	G	C	MI.2610	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	340	114	A	P	Gca/Cca	-2,65	0	0	probably_damaging	0,92	neutral	0,06	neutral	2,66	deleterious	-3,52	neutral	-1,98	medium_impact	3,34	damaging	0,59	neutral	0,32	deleterious	3,59	23,2	0,14	0,55	disease	0,72	disease	0,68	neutral	0,5	neutral	0,48	0	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,78	low_impact	-1,76	medium_impact	-0,47	medium_impact	1,99	0,73	0,9	7,02	9,53	N	0,36	N	0,67	polymorphism	0,99	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6244	6244	C	A	MI.2611	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	341	114	A	E	gCa/gAa	3,6	1	0	possibly_damaging	0,89	neutral	0,12	neutral	2,66	deleterious	-3,23	neutral	-1,73	medium_impact	3,34	neutral	0,61	neutral	0,4	deleterious	4,26	23,9	0,15	0,55	disease	0,55	disease	0,54	neutral	0,49	neutral	0,5	0	neutral	0,96	neutral	0,12	NA	0	deleterious	0,71	low_impact	-1,61	medium_impact	-0,29	medium_impact	1,99	0,67	0,9	7,02	9,53	P	0,61	P	0,73	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6244	6244	C	T	MI.2612	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	341	114	A	V	gCa/gTa	3,6	1	0	possibly_damaging	0,73	neutral	0,33	neutral	2,91	neutral	0,74	neutral	-0,61	neutral_impact	0,64	neutral	0,67	neutral	0,61	neutral	1,5	13,34	0,32	0,55	neutral	0,37	neutral	0,24	neutral	0,24	neutral	0,44	1	neutral	0,77	neutral	0,3	neutral	-3	deleterious	0,58	low_impact	-1,16	medium_impact	0,02	medium_impact	-0,51	0,7	0,9	7,02	9,53	P	0,58	P	0,6	disease_causing	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6244	6244	C	G	MI.2613	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	341	114	A	G	gCa/gGa	3,6	1	0	benign	0	neutral	0,19	neutral	2,7	neutral	-1,52	neutral	-1,76	low_impact	0,88	neutral	0,64	neutral	0,56	deleterious	0,69	8,76	0,22	0,55	neutral	0,44	neutral	0,22	neutral	0,33	neutral	0,4	2	neutral	0,81	deleterious	0,6	neutral	-6	neutral	0,15	high_impact	2,07	medium_impact	-0,16	medium_impact	-0,29	0,63	0,9	7,02	9,53	P	0,61	P	0,54	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6246	6246	T	G	MI.2614	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	343	115	S	A	Tct/Gct	-9,13	0	0	probably_damaging	0,99	neutral	0,05	neutral	2,61	neutral	-2,5	neutral	-2,23	high_impact	3,62	neutral	0,64	damaging	0,17	deleterious	3,6	23,2	0,26	0,55	neutral	0,33	neutral	0,42	disease	0,59	neutral	0,43	1	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,7	low_impact	-2,64	medium_impact	-0,52	high_impact	2,24	0,55	0,9	1,95	6,85	N	0,38	N	0,35	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6246	6246	T	A	MI.2615	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	343	115	S	T	Tct/Act	-9,13	0	0	probably_damaging	0,99	deleterious	0,01	neutral	2,62	neutral	-2,31	neutral	-2,37	high_impact	4,12	damaging	0,55	damaging	0,15	deleterious	3,69	23,3	0,26	0,55	neutral	0,41	disease	0,51	disease	0,6	disease	0,62	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,68	low_impact	-2,64	medium_impact	-0,92	high_impact	2,71	0,64	0,9	1,95	6,85	N	0,35	N	0,43	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6246	6246	T	C	MI.2616	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	343	115	S	P	Tct/Cct	-9,13	0	0	probably_damaging	1	deleterious	0	neutral	2,59	neutral	-2,83	deleterious	-3,9	high_impact	4,36	damaging	0,44	damaging	0,19	deleterious	3,86	23,5	0,2	0,55	disease	0,7	disease	0,76	disease	0,78	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,93	0,63	0,9	1,95	6,85	P	0,58	P	0,91	polymorphism	0,97	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6247	6247	C	A	MI.2617	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	344	115	S	Y	tCt/tAt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-4,29	deleterious	-4,72	high_impact	5,16	damaging	0,56	damaging	0,12	deleterious	3,97	23,6	0,16	0,55	disease	0,67	disease	0,75	disease	0,71	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,59	0,9	1,95	6,85	P	0,7	P	0,92	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6247	6247	C	T	MI.2618	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	344	115	S	F	tCt/tTt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-4,13	deleterious	-4,72	high_impact	5,16	damaging	0,42	damaging	0,08	deleterious	3,98	23,6	0,15	0,55	disease	0,53	disease	0,78	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,44	0,9	1,95	6,85	P	0,71	P	0,98	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6247	6247	C	G	MI.2619	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	344	115	S	C	tCt/tGt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-5,39	deleterious	-3,94	high_impact	4,82	damaging	0,53	damaging	0,12	deleterious	3,42	23	0,21	0,55	disease	0,65	disease	0,66	disease	0,66	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	3,35	0,56	0,9	1,95	6,85	P	0,7	P	0,85	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8648	8648	G	C	MI.262	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	122	41	R	P	cGa/cCa	2,9	0,74	0	probably_damaging	1	deleterious	0,02	neutral	4,18	deleterious	-3,32	deleterious	-6,33	medium_impact	2,93	damaging	0,47	neutral	0,37	deleterious	4,09	23,7	0,14	0,65	disease	0,83	disease	0,89	disease	0,83	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,89	low_impact	-3,6	medium_impact	-0,66	medium_impact	1,41	0,27	0,9	44,69	8,36	N	0,46	N	1	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6249	6249	G	C	MI.2620	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	346	116	A	P	Gct/Cct	-13,06	0	0	benign	0,33	neutral	0,07	neutral	2,74	neutral	-1,84	neutral	-2,14	medium_impact	2,52	damaging	0,52	neutral	0,38	deleterious	3,51	23,1	0,11	0,55	disease	0,74	disease	0,84	disease	0,58	disease	0,78	6	neutral	0,92	neutral	0,37	neutral	-3	deleterious	0,44	medium_impact	-0,47	medium_impact	-0,43	medium_impact	1,23	0,83	0,9	12,87	68,74	N	0,35	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6249	6249	G	T	MI.2621	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	346	116	A	S	Gct/Tct	-13,06	0	0	benign	0	neutral	1	neutral	2,77	neutral	-0,63	neutral	1,13	neutral_impact	-1,16	neutral	0,7	neutral	0,93	neutral	-0,9	0,03	0,42	0,55	neutral	0,29	neutral	0,07	neutral	0,2	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,07	high_impact	1,86	low_impact	-2,17	0,83	0,9	12,87	68,74	N	0,42	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6249	6249	G	A	MI.2622	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	346	116	A	T	Gct/Act	-13,06	0	0	benign	0	neutral	0,09	neutral	2,77	neutral	-0,66	neutral	-0,72	low_impact	0,94	neutral	0,71	neutral	0,68	deleterious	2,15	17,2	0,38	0,55	neutral	0,33	neutral	0,35	neutral	0,26	neutral	0,46	1	neutral	0,91	deleterious	0,55	neutral	-6	neutral	0,13	high_impact	2,07	medium_impact	-0,37	medium_impact	-0,23	0,77	0,9	12,87	68,74	N	0,5	N	0,2	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6250	6250	C	T	MI.2623	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	347	116	A	V	gCt/gTt	2,44	0,99	0	benign	0,13	neutral	0,13	neutral	2,88	neutral	0,78	neutral	-2,43	medium_impact	1,94	neutral	0,69	neutral	0,75	deleterious	2,45	19,16	0,33	0,55	neutral	0,35	disease	0,54	neutral	0,4	neutral	0,46	1	neutral	0,85	deleterious	0,5	neutral	-3	neutral	0,2	medium_impact	0,02	medium_impact	-0,27	medium_impact	0,69	0,83	0,9	12,87	68,74	P	0,51	P	0,66	polymorphism	0,98	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6250	6250	C	G	MI.2624	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	347	116	A	G	gCt/gGt	2,44	0,99	0	benign	0,13	neutral	0,16	neutral	2,76	neutral	-0,87	neutral	-1,13	neutral_impact	0,39	neutral	0,7	neutral	0,71	deleterious	0,83	9,63	0,28	0,55	disease	0,67	neutral	0,43	neutral	0,39	disease	0,63	3	neutral	0,82	deleterious	0,52	neutral	-6	neutral	0,24	medium_impact	0,02	medium_impact	-0,21	medium_impact	-0,74	0,77	0,9	12,87	68,74	N	0,49	N	0,24	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6250	6250	C	A	MI.2625	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	347	116	A	D	gCt/gAt	2,44	0,99	0	benign	0,2	deleterious	0,04	neutral	2,72	deleterious	-3,42	neutral	-1,7	medium_impact	2,98	damaging	0,57	neutral	0,47	deleterious	3,98	23,6	0,17	0,55	disease	0,78	disease	0,83	disease	0,57	disease	0,77	5	neutral	0,95	neutral	0,42	deleterious	1	neutral	0,35	medium_impact	-0,19	medium_impact	-0,58	medium_impact	1,65	0,72	0,9	12,87	68,74	N	0,46	N	0,4	polymorphism	0,93	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6252	6252	A	C	MI.2626	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	349	117	M	L	Ata/Cta	-9,82	0	0	benign	0	neutral	0,66	neutral	3,13	neutral	1,26	neutral	-0,4	neutral_impact	-0,46	neutral	0,77	neutral	0,83	neutral	-1,38	0	0,57	0,6	neutral	0,27	neutral	0,27	neutral	0,26	neutral	0,44	1	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,35	low_impact	-1,52	0,58	0,9	15,79	29,72	N	0,38	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6252	6252	A	T	MI.2627	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	349	117	M	L	Ata/Tta	-9,82	0	0	benign	0	neutral	0,66	neutral	3,13	neutral	1,26	neutral	-0,4	neutral_impact	-0,46	neutral	0,77	neutral	0,83	neutral	-1,23	0,01	0,57	0,6	neutral	0,27	neutral	0,27	neutral	0,26	neutral	0,44	1	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,35	low_impact	-1,52	0,58	0,9	15,79	29,72	N	0,38	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6252	6252	A	G	MI.2628	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	349	117	M	V	Ata/Gta	-9,82	0	0	benign	0	neutral	0,29	neutral	2,89	neutral	0,54	neutral	-0,93	low_impact	1,5	neutral	0,78	neutral	0,84	neutral	-0,62	0,11	0,59	0,65	neutral	0,18	neutral	0,39	neutral	0,38	neutral	0,44	1	neutral	0,71	deleterious	0,65	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	-0,02	medium_impact	0,29	0,61	0,9	15,79	29,72	N	0,41	N	0,02	polymorphism	1	0,02	rs878927119	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6253	6253	T	C	MI.2629	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	350	117	M	T	aTa/aCa	4,06	0,99	0,05	benign	0	neutral	0,37	neutral	2,79	neutral	-0,56	neutral	-2,08	medium_impact	2,12	neutral	0,79	neutral	0,98	neutral	-0,64	0,1	0,5	0,55	neutral	0,31	neutral	0,36	neutral	0,49	neutral	0,45	1	neutral	0,63	deleterious	0,69	neutral	-3	neutral	0,13	high_impact	2,07	medium_impact	0,06	medium_impact	0,86	0,34	0,9	15,79	29,72	P	0,67	P	0,01	polymorphism	1	0,03	rs200165736	.	.	.	.	.	.	.	14,09	T6253C	Prostate Cancer/enriched in POAG cohort	+	-	Reported	3
chrM	8648	8648	G	A	MI.263	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	122	41	R	Q	cGa/cAa	2,9	0,74	0	probably_damaging	0,99	deleterious	0,02	neutral	4,23	neutral	-1,69	deleterious	-3,62	medium_impact	3,19	neutral	0,69	neutral	0,37	deleterious	4,31	24	0,3	0,65	disease	0,65	disease	0,83	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,81	low_impact	-2,65	medium_impact	-0,66	medium_impact	1,64	0,81	0,9	44,69	8,36	N	0,36	N	1	disease_causing	1	0,09	rs28479867	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6253	6253	T	A	MI.2630	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	350	117	M	K	aTa/aAa	4,06	0,99	0,05	benign	0,01	neutral	0,16	neutral	2,76	neutral	-2,07	deleterious	-2,75	medium_impact	3,24	neutral	0,66	neutral	0,41	deleterious	0,69	8,75	0,28	0,55	disease	0,53	disease	0,69	disease	0,66	disease	0,71	4	neutral	0,84	deleterious	0,58	neutral	-3	neutral	0,23	medium_impact	1,12	medium_impact	-0,21	medium_impact	1,89	0,64	0,9	15,79	29,72	P	0,53	P	0,69	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6254	6254	A	T	MI.2631	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	351	117	M	I	atA/atT	2,21	0,98	0	benign	0	neutral	0,31	neutral	2,86	neutral	0,27	neutral	-0,75	neutral_impact	0,36	neutral	0,69	neutral	0,69	neutral	-0,36	0,49	0,55	0,6	neutral	0,23	neutral	0,3	neutral	0,34	neutral	0,43	1	neutral	0,69	deleterious	0,66	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0	medium_impact	-0,77	0,68	0,9	15,79	29,72	P	0,56	P	0,19	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6254	6254	A	C	MI.2632	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	351	117	M	I	atA/atC	2,21	0,98	0	benign	0	neutral	0,31	neutral	2,86	neutral	0,27	neutral	-0,75	neutral_impact	0,36	neutral	0,69	neutral	0,69	neutral	-0,52	0,2	0,55	0,6	neutral	0,23	neutral	0,3	neutral	0,34	neutral	0,43	1	neutral	0,69	deleterious	0,66	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0	medium_impact	-0,77	0,68	0,9	15,79	29,72	P	0,57	P	0,19	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6255	6255	G	T	MI.2633	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	352	118	V	L	Gtg/Ttg	-0,57	0,05	0	benign	0	deleterious	0,01	neutral	2,9	neutral	-0,63	neutral	-1,84	medium_impact	2,21	damaging	0,59	neutral	0,53	neutral	1,55	13,61	0,46	0,55	neutral	0,3	disease	0,73	neutral	0,32	neutral	0,49	0	deleterious	0,99	deleterious	0,51	deleterious	1	neutral	0,18	high_impact	2,07	medium_impact	-0,92	medium_impact	0,94	0,65	0,9	10,92	27,38	N	0,46	N	0,55	polymorphism	0,79	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6255	6255	G	A	MI.2634	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	352	118	V	M	Gtg/Atg	-0,57	0,05	0	possibly_damaging	0,65	deleterious	0,01	neutral	2,7	neutral	-2,56	neutral	-1,96	medium_impact	2,38	neutral	0,62	neutral	0,61	neutral	1,63	14,01	0,42	0,55	disease	0,53	disease	0,69	neutral	0,35	neutral	0,49	0	deleterious	0,99	neutral	0,18	deleterious	4	deleterious	0,51	low_impact	-1,01	medium_impact	-0,92	medium_impact	1,1	0,7	0,9	10,92	27,38	N	0,39	N	0,82	polymorphism	0,76	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6255	6255	G	C	MI.2635	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	352	118	V	L	Gtg/Ctg	-0,57	0,05	0	benign	0	deleterious	0,01	neutral	2,9	neutral	-0,63	neutral	-1,84	medium_impact	2,21	damaging	0,59	neutral	0,53	neutral	1,4	12,8	0,46	0,55	neutral	0,3	disease	0,73	neutral	0,32	neutral	0,49	0	deleterious	0,99	deleterious	0,51	deleterious	1	neutral	0,18	high_impact	2,07	medium_impact	-0,92	medium_impact	0,94	0,65	0,9	10,92	27,38	N	0,46	N	0,55	polymorphism	0,79	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6256	6256	T	A	MI.2636	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	353	118	V	E	gTg/gAg	1,52	0,98	0	probably_damaging	0,97	deleterious	0	neutral	2,67	deleterious	-4,01	deleterious	-4,34	high_impact	3,86	neutral	0,63	neutral	0,48	deleterious	4,62	24,5	0,12	0,55	disease	0,65	disease	0,88	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,81	low_impact	-2,18	low_impact	-1,48	high_impact	2,47	0,57	0,9	10,92	27,38	N	0,51	P	0,84	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6256	6256	T	C	MI.2637	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	353	118	V	A	gTg/gCg	1,52	0,98	0	benign	0,41	deleterious	0	neutral	2,75	neutral	-1,66	deleterious	-2,71	medium_impact	3,1	neutral	0,67	neutral	0,64	neutral	1,76	14,73	0,33	0,55	neutral	0,31	disease	0,61	disease	0,57	disease	0,57	1	deleterious	1	neutral	0,3	deleterious	1	neutral	0,3	medium_impact	-0,61	low_impact	-1,48	medium_impact	1,76	0,38	0,9	10,92	27,38	N	0,48	N	0,47	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6256	6256	T	G	MI.2638	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	353	118	V	G	gTg/gGg	1,52	0,98	0	probably_damaging	0,98	deleterious	0	neutral	2,65	deleterious	-3,68	deleterious	-5,09	medium_impact	3,4	neutral	0,62	neutral	0,6	deleterious	3,65	23,2	0,17	0,55	neutral	0,29	disease	0,79	disease	0,62	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,69	low_impact	-2,35	low_impact	-1,48	high_impact	2,04	0,61	0,9	10,92	27,38	N	0,45	N	0,71	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6258	6258	G	A	MI.2639	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	355	119	E	K	Gag/Aag	-7,97	0	0	probably_damaging	0,97	deleterious	0,01	neutral	2,87	neutral	-1,59	deleterious	-2,62	high_impact	3,73	damaging	0,48	neutral	0,36	deleterious	4,31	24	0,4	0,55	neutral	0,32	disease	0,86	disease	0,52	disease	0,62	2	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,79	low_impact	-2,18	medium_impact	-0,92	high_impact	2,35	0,74	0,9	3,31	8	N	0,46	N	0,72	polymorphism	0,89	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8648	8648	G	T	MI.264	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	122	41	R	L	cGa/cTa	2,9	0,74	0	probably_damaging	0,99	neutral	0,07	neutral	4,2	neutral	-2,61	deleterious	-6,29	high_impact	3,8	damaging	0,58	neutral	0,36	deleterious	4,15	23,8	0,29	0,65	disease	0,76	disease	0,91	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,86	low_impact	-2,65	medium_impact	-0,34	high_impact	2,16	0,23	0,9	44,69	8,36	N	0,47	N	1	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6258	6258	G	C	MI.2640	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	355	119	E	Q	Gag/Cag	-7,97	0	0	probably_damaging	0,98	deleterious	0	neutral	2,87	neutral	-1,69	neutral	-1,95	high_impact	4,01	damaging	0,56	neutral	0,52	deleterious	3,23	22,8	0,55	0,6	neutral	0,36	disease	0,71	neutral	0,36	neutral	0,49	0	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,75	low_impact	-2,35	low_impact	-1,48	high_impact	2,6	0,7	0,9	3,31	8	N	0,48	N	0,66	polymorphism	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6259	6259	A	T	MI.2641	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	356	119	E	V	gAg/gTg	9,15	1	0	probably_damaging	0,99	deleterious	0	neutral	2,82	deleterious	-3,32	deleterious	-4,93	high_impact	3,9	damaging	0,49	neutral	0,42	deleterious	4,29	24	0,25	0,55	disease	0,56	disease	0,85	disease	0,59	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,64	low_impact	-1,48	high_impact	2,5	0,61	0,9	3,31	8	P	0,54	P	0,67	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6259	6259	A	C	MI.2642	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	356	119	E	A	gAg/gCg	9,15	1	0	probably_damaging	0,98	deleterious	0	neutral	2,86	neutral	-1,95	deleterious	-4	high_impact	4,01	damaging	0,59	neutral	0,5	deleterious	3,74	23,3	0,31	0,55	neutral	0,38	disease	0,73	neutral	0,5	neutral	0,47	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,35	low_impact	-1,48	high_impact	2,6	0,68	0,9	3,31	8	P	0,5	N	0,71	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6259	6259	A	G	MI.2643	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	356	119	E	G	gAg/gGg	9,15	1	0	probably_damaging	0,99	neutral	0,1	neutral	3,32	neutral	1,55	deleterious	-4,13	low_impact	1,48	damaging	0,47	neutral	0,59	deleterious	4,24	23,9	0,38	0,55	neutral	0,24	disease	0,62	neutral	0,39	neutral	0,4	2	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,73	low_impact	-2,64	medium_impact	-0,34	medium_impact	0,27	0,55	0,9	3,31	8	P	0,61	P	0,67	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6260	6260	G	T	MI.2644	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	357	119	E	D	gaG/gaT	8,69	1	0,01	possibly_damaging	0,9	neutral	0,21	neutral	2,91	neutral	-0,87	neutral	-1,53	low_impact	1,7	damaging	0,45	neutral	0,6	deleterious	2,59	20,2	0,44	0,55	neutral	0,4	disease	0,58	neutral	0,28	neutral	0,44	1	neutral	0,93	neutral	0,16	neutral	-3	deleterious	0,69	low_impact	-1,65	medium_impact	-0,13	medium_impact	0,47	0,8	0,9	3,31	8	P	0,7	P	0,69	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6260	6260	G	C	MI.2645	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	357	119	E	D	gaG/gaC	8,69	1	0,01	possibly_damaging	0,9	neutral	0,21	neutral	2,91	neutral	-0,87	neutral	-1,53	low_impact	1,7	damaging	0,45	neutral	0,6	deleterious	2,43	19	0,44	0,55	neutral	0,4	disease	0,58	neutral	0,28	neutral	0,44	1	neutral	0,93	neutral	0,16	neutral	-3	deleterious	0,69	low_impact	-1,65	medium_impact	-0,13	medium_impact	0,47	0,8	0,9	3,31	8	P	0,71	P	0,69	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6261	6261	G	C	MI.2646	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	358	120	A	P	Gcc/Ccc	1,75	1	0,01	probably_damaging	1	neutral	0,11	neutral	2,77	neutral	-2,19	neutral	-1,11	low_impact	1,42	damaging	0,59	neutral	0,35	deleterious	2,13	17,05	0,2	0,55	disease	0,54	disease	0,76	neutral	0,27	disease	0,53	1	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,82	low_impact	-3,58	medium_impact	-0,31	medium_impact	0,21	0,68	0,9	2,92	8,24	N	0,48	N	0,85	disease_causing	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6261	6261	G	A	MI.2647	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	358	120	A	T	Gcc/Acc	1,75	1	0,01	probably_damaging	0,99	neutral	0,15	neutral	2,82	neutral	-0,52	neutral	0,27	neutral_impact	-0,4	neutral	0,61	neutral	0,57	neutral	1,08	11,11	0,38	0,55	neutral	0,26	neutral	0,25	neutral	0,16	neutral	0,43	1	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,66	low_impact	-2,64	medium_impact	-0,23	low_impact	-1,47	0,68	0,9	2,92	8,24	P	0,69	P	0,2	disease_causing	0,91	0,01	rs201262114	Likely benign	not_provided	RCV000224375.1	MedGen	.	.	CPD	0,15	G6261A	Prostate Cancer/LHON	+	-	Reported	3
chrM	6261	6261	G	T	MI.2648	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	358	120	A	S	Gcc/Tcc	1,75	1	0,01	probably_damaging	0,99	neutral	0,66	neutral	2,82	neutral	-0,19	neutral	1,09	neutral_impact	-1,8	neutral	0,68	neutral	0,83	neutral	-1	0,02	0,32	0,55	neutral	0,19	neutral	0,11	neutral	0,11	neutral	0,26	5	deleterious	0,99	neutral	0,34	neutral	-2	deleterious	0,64	low_impact	-2,64	medium_impact	0,35	low_impact	-2,76	0,73	0,9	2,92	8,24	N	0,46	N	0,64	disease_causing	0,82	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6262	6262	C	A	MI.2649	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	359	120	A	D	gCc/gAc	7,53	1	0	probably_damaging	1	neutral	0,11	neutral	2,78	neutral	-0,77	neutral	-0,46	neutral_impact	0,72	neutral	0,61	neutral	0,35	neutral	1,62	13,96	0,22	0,55	neutral	0,36	disease	0,7	neutral	0,22	neutral	0,46	1	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,74	low_impact	-3,58	medium_impact	-0,31	medium_impact	-0,43	0,61	0,9	2,92	8,24	P	0,53	P	0,89	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8650	8650	C	A	MI.265	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	124	42	L	M	Cta/Ata	-10,75	0	0	probably_damaging	1	neutral	0,15	neutral	4,3	neutral	-0,88	neutral	-1,29	low_impact	1,92	neutral	0,89	neutral	0,85	deleterious	2,49	19,41	0,32	0,65	disease	0,66	neutral	0,21	neutral	0,24	neutral	0,47	1	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,72	low_impact	-3,6	medium_impact	-0,13	medium_impact	0,55	0,81	0,9	25,22	18,79	N	0,5	N	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6262	6262	C	T	MI.2650	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	359	120	A	V	gCc/gTc	7,53	1	0	probably_damaging	0,99	neutral	0,07	neutral	2,75	neutral	-1,26	neutral	-1,03	neutral_impact	0,36	neutral	0,61	neutral	0,38	neutral	1,39	12,76	0,35	0,55	neutral	0,26	neutral	0,37	neutral	0,27	neutral	0,45	1	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,67	low_impact	-2,64	medium_impact	-0,43	medium_impact	-0,77	0,58	0,9	2,92	8,24	P	0,62	P	0,75	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6262	6262	C	G	MI.2651	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	359	120	A	G	gCc/gGc	7,53	1	0	probably_damaging	0,97	neutral	0,25	neutral	2,9	neutral	1,06	neutral	-0,57	neutral_impact	-0,58	neutral	0,65	neutral	0,54	deleterious	0,8	9,46	0,29	0,55	neutral	0,16	neutral	0,25	neutral	0,16	neutral	0,42	2	neutral	0,98	neutral	0,14	neutral	-2	deleterious	0,64	low_impact	-2,18	medium_impact	-0,07	low_impact	-1,64	0,68	0,9	2,92	8,24	P	0,6	P	0,56	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6264	6264	G	C	MI.2652	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	361	121	G	R	Gga/Cga	-12,13	0	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-2,32	deleterious	-6,6	high_impact	5,28	damaging	0,44	damaging	0,02	deleterious	3,86	23,5	0,2	0,55	neutral	0,42	disease	0,86	disease	0,85	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,87	0,9	2,14	6,66	P	0,57	P	0,95	polymorphism	0,72	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6264	6264	G	T	MI.2653	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	361	121	G	W	Gga/Tga	-12,13	0	0	probably_damaging	1	deleterious	0	neutral	2,75	deleterious	-5,98	deleterious	-6,61	high_impact	5,28	damaging	0,42	damaging	0,02	deleterious	4,32	24	0,18	0,55	disease	0,92	disease	0,88	disease	0,77	disease	0,62	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,44	0,9	2,14	6,66	P	0,5	N	0,83	polymorphism	0,62	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6265	6265	G	T	MI.2654	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	362	121	G	V	gGa/gTa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,77	deleterious	-3,07	deleterious	-7,43	high_impact	5,28	damaging	0,48	damaging	0,03	deleterious	3,71	23,3	0,19	0,55	disease	0,63	disease	0,86	disease	0,74	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,56	0,9	2,14	6,66	P	0,65	P	0,93	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6265	6265	G	A	MI.2655	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	362	121	G	E	gGa/gAa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-1,77	deleterious	-6,6	high_impact	4,92	damaging	0,38	damaging	0,02	deleterious	3,77	23,4	0,27	0,55	neutral	0,46	disease	0,85	disease	0,83	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,51	0,9	2,14	6,66	P	0,76	P	0,93	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6265	6265	G	C	MI.2656	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	362	121	G	A	gGa/gCa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,91	neutral	-1,67	deleterious	-4,95	high_impact	4,38	damaging	0,58	damaging	0,04	deleterious	3,01	22,3	0,33	0,55	neutral	0,39	disease	0,71	disease	0,72	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,95	0,62	0,9	2,14	6,66	P	0,51	P	0,64	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6267	6267	G	T	MI.2657	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	364	122	A	S	Gca/Tca	-20	0	0	benign	0,23	neutral	0,2	neutral	2,74	neutral	-2,02	neutral	-1,85	low_impact	1,59	neutral	0,65	neutral	0,56	deleterious	2,31	18,21	0,44	0,55	neutral	0,42	disease	0,55	neutral	0,32	neutral	0,24	5	neutral	0,76	deleterious	0,49	neutral	-6	neutral	0,28	medium_impact	-0,26	medium_impact	-0,14	medium_impact	0,37	0,83	0,9	11,5	11,09	N	0,45	N	0,64	polymorphism	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6267	6267	G	C	MI.2658	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	364	122	A	P	Gca/Cca	-20	0	0	probably_damaging	0,93	neutral	0,16	neutral	2,64	neutral	-1,82	deleterious	-3,11	medium_impact	2,16	damaging	0,59	neutral	0,38	deleterious	3,74	23,3	0,32	0,55	neutral	0,24	disease	0,77	neutral	0,32	neutral	0,23	5	neutral	0,96	neutral	0,12	deleterious	1	deleterious	0,73	low_impact	-1,81	medium_impact	-0,21	medium_impact	0,9	0,75	0,9	11,5	11,09	N	0,38	N	0,85	polymorphism	0,8	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6267	6267	G	A	MI.2659	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	364	122	A	T	Gca/Aca	-20	0	0	benign	0,01	neutral	0,1	neutral	2,67	neutral	-2,4	neutral	-1,81	low_impact	1,92	damaging	0,54	neutral	0,59	deleterious	3,63	23,2	0,5	0,55	neutral	0,37	disease	0,55	neutral	0,35	neutral	0,22	6	neutral	0,9	deleterious	0,55	neutral	-6	neutral	0,21	medium_impact	1,12	medium_impact	-0,34	medium_impact	0,67	0,76	0,9	11,5	11,09	P	0,58	P	0,2	polymorphism	0,93	0,03	rs202216551	.	.	.	.	pancreatic cancer cell line	.	.	0,89	G6267A	Prostate Cancer	+	-	Reported	1
chrM	8650	8650	C	G	MI.266	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	124	42	L	V	Cta/Gta	-10,75	0	0	probably_damaging	0,99	neutral	0,15	neutral	4,3	neutral	-0,87	neutral	-1,87	medium_impact	2,21	neutral	0,89	neutral	0,84	deleterious	2,14	17,09	0,39	0,65	neutral	0,42	neutral	0,31	neutral	0,31	neutral	0,47	1	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,71	low_impact	-2,65	medium_impact	-0,13	medium_impact	0,8	0,66	0,9	25,22	18,79	N	0,51	P	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6268	6268	C	A	MI.2660	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	365	122	A	E	gCa/gAa	7,3	1	0	probably_damaging	0,94	deleterious	0	neutral	2,73	neutral	-2,96	deleterious	-3,09	high_impact	4,57	neutral	0,63	neutral	0,45	deleterious	4,38	24,1	0,26	0,55	disease	0,61	disease	0,79	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,81	low_impact	-1,88	low_impact	-1,48	high_impact	3,12	0,76	0,9	11,5	11,09	P	0,58	P	0,76	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6268	6268	C	T	MI.2661	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	365	122	A	V	gCa/gTa	7,3	1	0	benign	0,01	neutral	0,32	neutral	2,66	neutral	-2,13	neutral	-1,17	neutral_impact	0,56	neutral	0,61	neutral	0,71	deleterious	0,77	9,25	0,44	0,55	neutral	0,29	neutral	0,3	neutral	0,32	neutral	0,43	1	neutral	0,67	deleterious	0,66	neutral	-6	neutral	0,17	medium_impact	1,12	medium_impact	0,01	medium_impact	-0,58	0,64	0,9	11,5	11,09	P	0,64	P	0,75	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6268	6268	C	G	MI.2662	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	365	122	A	G	gCa/gGa	7,3	1	0	benign	0,15	deleterious	0,03	neutral	2,7	deleterious	-3,39	deleterious	-2,87	medium_impact	3,15	neutral	0,62	neutral	0,58	deleterious	2,24	17,76	0,37	0,55	disease	0,52	disease	0,6	disease	0,58	disease	0,64	3	neutral	0,97	neutral	0,44	deleterious	1	neutral	0,29	medium_impact	-0,05	medium_impact	-0,65	medium_impact	1,81	0,8	0,9	11,5	11,09	P	0,55	P	0,56	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6270	6270	G	T	MI.2663	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	367	123	G	W	Gga/Tga	-16,07	0	0	probably_damaging	1	deleterious	0	neutral	2,43	deleterious	-6,77	deleterious	-6,63	high_impact	5,21	damaging	0,41	damaging	0,02	deleterious	4,35	24,1	0,19	0,55	disease	0,88	disease	0,84	disease	0,74	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,71	0,44	0,9	2,73	6,66	N	0,43	N	0,83	polymorphism	0,74	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6270	6270	G	C	MI.2664	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	367	123	G	R	Gga/Cga	-16,07	0	0	probably_damaging	1	deleterious	0	neutral	2,49	neutral	-2,8	deleterious	-6,63	high_impact	5,21	damaging	0,43	damaging	0,02	deleterious	3,89	23,5	0,18	0,55	neutral	0,33	disease	0,83	disease	0,75	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,71	0,75	0,9	2,73	6,66	N	0,48	N	0,95	polymorphism	0,82	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6271	6271	G	A	MI.2665	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	368	123	G	E	gGa/gAa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,53	neutral	-2,01	deleterious	-6,63	high_impact	4,41	damaging	0,37	damaging	0,02	deleterious	3,81	23,4	0,23	0,55	neutral	0,3	disease	0,82	disease	0,69	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,97	0,38	0,9	2,73	6,66	P	0,61	P	0,93	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6271	6271	G	C	MI.2666	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	368	123	G	A	gGa/gCa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,55	neutral	-1,78	deleterious	-4,97	medium_impact	3,24	damaging	0,58	damaging	0,04	deleterious	3,04	22,3	0,26	0,55	neutral	0,36	disease	0,67	disease	0,65	disease	0,66	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	medium_impact	1,89	0,44	0,9	2,73	6,66	N	0,46	N	0,64	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6271	6271	G	T	MI.2667	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	368	123	G	V	gGa/gTa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-3,77	deleterious	-7,46	high_impact	5,21	damaging	0,47	damaging	0,03	deleterious	3,67	23,2	0,19	0,55	disease	0,53	disease	0,84	disease	0,7	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,71	0,46	0,9	2,73	6,66	P	0,61	P	0,93	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6273	6273	A	G	MI.2668	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	370	124	T	A	Aca/Gca	-7,04	0	0	probably_damaging	0,98	deleterious	0,03	neutral	2,81	neutral	-1,36	deleterious	-3,15	medium_impact	2,5	neutral	0,72	damaging	0,06	deleterious	3,39	23	0,5	0,55	neutral	0,23	neutral	0,45	neutral	0,38	neutral	0,36	3	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,69	low_impact	-2,35	medium_impact	-0,65	medium_impact	1,21	0,33	0,9	2,53	6,75	N	0,3	N	0,69	polymorphism	0,97	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6273	6273	A	C	MI.2669	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	370	124	T	P	Aca/Cca	-7,04	0	0	probably_damaging	1	deleterious	0	neutral	2,69	deleterious	-3,82	deleterious	-4,22	high_impact	4,79	damaging	0,59	damaging	0,07	deleterious	3,46	23	0,27	0,55	disease	0,75	disease	0,73	neutral	0,5	neutral	0,49	0	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,32	0,27	0,9	2,53	6,75	P	0,56	P	0,92	polymorphism	0,88	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8651	8651	T	G	MI.267	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	125	42	L	R	cTa/cGa	-7,04	0	0	probably_damaging	1	neutral	0,06	neutral	4,21	deleterious	-3,05	deleterious	-4,75	high_impact	3,62	neutral	0,75	damaging	0,12	deleterious	4,05	23,7	0,19	0,65	disease	0,82	disease	0,79	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,38	high_impact	2,01	0,54	0,9	25,22	18,79	N	0,28	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6273	6273	A	T	MI.2670	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	370	124	T	S	Aca/Tca	-7,04	0	0	probably_damaging	0,98	deleterious	0,03	neutral	2,73	neutral	-2,45	deleterious	-2,68	medium_impact	3,29	neutral	0,69	damaging	0,07	deleterious	3,23	22,8	0,39	0,55	disease	0,53	disease	0,59	disease	0,51	neutral	0,4	2	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,75	low_impact	-2,35	medium_impact	-0,65	medium_impact	1,94	0,32	0,9	2,53	6,75	N	0,27	N	0,79	polymorphism	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6274	6274	C	T	MI.2671	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	371	124	T	M	aCa/aTa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,73	neutral	-2,58	deleterious	-4,37	high_impact	4,58	neutral	0,7	damaging	0,05	deleterious	3,91	23,5	0,33	0,55	disease	0,63	disease	0,69	disease	0,66	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	3,13	0,49	0,9	2,53	6,75	P	0,53	P	0,96	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6274	6274	C	A	MI.2672	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	371	124	T	K	aCa/aAa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-1,94	deleterious	-4,34	high_impact	5,13	neutral	0,64	damaging	0,04	deleterious	4,42	24,2	0,3	0,55	disease	0,64	disease	0,77	disease	0,76	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,64	0,57	0,9	2,53	6,75	P	0,75	P	0,88	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6276	6276	G	T	MI.2673	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	373	125	G	C	Ggt/Tgt	-4,96	0	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-5,93	deleterious	-7,47	high_impact	5,29	damaging	0,4	damaging	0,03	deleterious	4,07	23,7	0,18	0,55	disease	0,83	disease	0,88	disease	0,67	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,56	0,9	3,51	6,82	P	0,49	N	0,98	polymorphism	0,7	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6276	6276	G	A	MI.2674	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	373	125	G	S	Ggt/Agt	-4,96	0	0	probably_damaging	1	neutral	0,09	neutral	2,54	neutral	-2,85	deleterious	-4,98	high_impact	3,98	damaging	0,48	damaging	0,05	deleterious	4,08	23,7	0,25	0,55	disease	0,58	disease	0,8	disease	0,63	disease	0,56	1	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,85	low_impact	-3,58	medium_impact	-0,37	high_impact	2,58	0,63	0,9	3,51	6,82	N	0,33	N	0,73	polymorphism	0,91	0,36	rs879156031	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6276	6276	G	C	MI.2675	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	373	125	G	R	Ggt/Cgt	-4,96	0	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-3,63	deleterious	-6,64	high_impact	5,29	damaging	0,45	damaging	0,03	deleterious	3,9	23,5	0,22	0,55	disease	0,75	disease	0,86	disease	0,82	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,75	0,9	3,51	6,82	P	0,61	P	0,95	polymorphism	0,82	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6277	6277	G	T	MI.2676	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	374	125	G	V	gGt/gTt	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-4,15	deleterious	-7,47	high_impact	5,29	damaging	0,5	damaging	0,04	deleterious	3,7	23,3	0,18	0,55	disease	0,51	disease	0,87	disease	0,74	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,55	0,9	3,51	6,82	P	0,62	P	0,93	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6277	6277	G	A	MI.2677	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	374	125	G	D	gGt/gAt	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-3,16	deleterious	-5,81	high_impact	4,75	damaging	0,28	damaging	0,03	deleterious	3,73	23,3	0,18	0,55	disease	0,82	disease	0,86	disease	0,76	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,41	0,9	3,51	6,82	P	0,85	P	0,97	disease_causing_automatic	1	0,5	rs281865417	Pathogenic	Familial_colorectal_cancer	RCV000010310.2	MedGen	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	6277	6277	G	C	MI.2678	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	374	125	G	A	gGt/gCt	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-3,45	deleterious	-4,98	high_impact	4,32	damaging	0,6	damaging	0,06	deleterious	3	22,2	0,25	0,55	disease	0,56	disease	0,72	disease	0,71	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,89	0,7	0,9	3,51	6,82	P	0,51	P	0,64	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6279	6279	T	G	MI.2679	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	376	126	W	G	Tga/Gga	-14,91	0	0	probably_damaging	1	deleterious	0	neutral	2	deleterious	-7,74	deleterious	-10,79	high_impact	5,31	neutral	0,61	damaging	0,08	deleterious	3,88	23,5	0,18	0,55	neutral	0,41	disease	0,86	disease	0,81	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,21	0,9	1,95	6,71	N	0,49	N	0,89	polymorphism	0,97	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8651	8651	T	C	MI.268	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	125	42	L	P	cTa/cCa	-7,04	0	0	probably_damaging	1	neutral	0,06	neutral	4,2	deleterious	-3,68	deleterious	-5,15	medium_impact	3,07	neutral	0,75	damaging	0,17	deleterious	3,77	23,4	0,16	0,65	disease	0,87	disease	0,82	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,89	low_impact	-3,6	medium_impact	-0,38	medium_impact	1,53	0,43	0,9	25,22	18,79	N	0,25	N	0,95	polymorphism	0,85	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6279	6279	T	C	MI.2680	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	376	126	W	R	Tga/Cga	-14,91	0	0	probably_damaging	1	deleterious	0	neutral	2	deleterious	-7,32	deleterious	-11,62	high_impact	5,31	neutral	0,61	damaging	0,08	deleterious	3,56	23,1	0,22	0,55	disease	0,9	disease	0,93	disease	0,84	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,17	0,9	1,95	6,71	N	0,5	N	0,98	polymorphism	0,99	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6280	6280	G	T	MI.2681	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	377	126	W	L	tGa/tTa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,13	deleterious	-5,29	deleterious	-10,79	high_impact	5,31	damaging	0,56	damaging	0,1	deleterious	4,15	23,8	0,15	0,55	disease	0,78	disease	0,87	disease	0,78	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,16	0,9	1,95	6,71	P	0,59	P	0,95	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6280	6280	G	C	MI.2682	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	377	126	W	S	tGa/tCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,01	deleterious	-6,48	deleterious	-11,62	high_impact	4,76	neutral	0,68	damaging	0,09	deleterious	3,89	23,5	0,16	0,55	disease	0,86	disease	0,94	disease	0,79	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,17	0,9	1,95	6,71	P	0,52	P	0,89	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6281	6281	A	T	MI.2683	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	378	126	W	C	tgA/tgT	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2	deleterious	-8,33	deleterious	-10,79	high_impact	5,31	damaging	0,6	damaging	0,07	deleterious	4,04	23,7	0,21	0,55	disease	0,95	disease	0,93	disease	0,81	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,19	0,9	1,95	6,71	P	0,53	P	0,88	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6281	6281	A	C	MI.2684	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	378	126	W	C	tgA/tgC	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2	deleterious	-8,33	deleterious	-10,79	high_impact	5,31	damaging	0,6	damaging	0,07	deleterious	3,92	23,5	0,21	0,55	disease	0,95	disease	0,93	disease	0,81	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,19	0,9	1,95	6,71	P	0,52	P	0,88	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6282	6282	A	T	MI.2685	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	379	127	T	S	Aca/Tca	0,82	0,99	0	probably_damaging	0,99	deleterious	0	neutral	2,52	deleterious	-3,64	deleterious	-3,32	high_impact	5,28	neutral	0,74	damaging	0,17	deleterious	3,27	22,8	0,33	0,55	disease	0,68	disease	0,66	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	3,78	0,77	0,9	2,34	6,87	P	0,67	P	0,79	disease_causing	0,97	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6282	6282	A	G	MI.2686	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	379	127	T	A	Aca/Gca	0,82	0,99	0	probably_damaging	0,99	deleterious	0	neutral	2,52	deleterious	-3	deleterious	-4,15	high_impact	4,93	neutral	0,61	damaging	0,16	deleterious	3,43	23	0,39	0,55	disease	0,59	disease	0,61	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	3,45	0,63	0,9	2,34	6,87	P	0,67	P	0,69	disease_causing	0,99	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6282	6282	A	C	MI.2687	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	379	127	T	P	Aca/Cca	0,82	0,99	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-5,24	deleterious	-4,98	high_impact	4,93	damaging	0,59	damaging	0,13	deleterious	3,48	23,1	0,15	0,55	disease	0,84	disease	0,74	disease	0,68	disease	0,64	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,65	0,9	2,34	6,87	P	0,63	P	0,92	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6283	6283	C	T	MI.2688	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	380	127	T	M	aCa/aTa	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-3,83	deleterious	-4,98	high_impact	4,73	neutral	0,75	damaging	0,13	deleterious	3,92	23,5	0,27	0,55	neutral	0,36	disease	0,73	disease	0,7	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	high_impact	3,27	0,75	0,9	2,34	6,87	P	0,63	P	0,96	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6283	6283	C	A	MI.2689	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	380	127	T	K	aCa/aAa	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-4,37	deleterious	-4,98	high_impact	5,28	neutral	0,63	damaging	0,11	deleterious	4,42	24,2	0,15	0,55	disease	0,76	disease	0,79	disease	0,77	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,73	0,9	2,34	6,87	P	0,74	P	0,88	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8651	8651	T	A	MI.269	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	125	42	L	Q	cTa/cAa	-7,04	0	0	probably_damaging	1	neutral	0,05	neutral	4,2	deleterious	-3,19	deleterious	-4,62	medium_impact	2,93	neutral	0,8	damaging	0,16	deleterious	4,05	23,7	0,21	0,65	disease	0,84	disease	0,69	disease	0,59	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,43	medium_impact	1,41	0,51	0,9	25,22	18,79	N	0,27	N	0,92	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6285	6285	G	T	MI.2690	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	382	128	V	F	Gtc/Ttc	-11,67	0	0	possibly_damaging	0,7	neutral	0,07	neutral	3	neutral	0,36	deleterious	-3,71	medium_impact	3,19	damaging	0,53	neutral	0,5	deleterious	3,64	23,2	0,21	0,55	neutral	0,23	disease	0,87	neutral	0,45	disease	0,7	4	neutral	0,94	neutral	0,19	NA	0	deleterious	0,67	low_impact	-1,1	medium_impact	-0,43	medium_impact	1,85	0,71	0,9	0,97	7,02	N	0,46	N	0,86	polymorphism	0,82	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6285	6285	G	A	MI.2691	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	382	128	V	I	Gtc/Atc	-11,67	0	0	benign	0,1	neutral	0,22	neutral	2,93	neutral	-0,12	neutral	-0,46	low_impact	1,22	damaging	0,53	neutral	0,64	deleterious	0,57	7,94	0,52	0,6	neutral	0,34	neutral	0,25	neutral	0,22	neutral	0,41	2	neutral	0,75	deleterious	0,56	neutral	-6	neutral	0,2	medium_impact	0,14	medium_impact	-0,11	medium_impact	0,03	0,95	1	0,97	7,02	P	0,63	P	0,24	polymorphism	0,99	0,02	rs878947044	.	.	.	.	.	.	.	.	G6285A	Prostate Cancer	+	-	Reported	1
chrM	6285	6285	G	C	MI.2692	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	382	128	V	L	Gtc/Ctc	-11,67	0	0	benign	0	neutral	0,09	neutral	3,02	neutral	0,36	neutral	-2,01	low_impact	1,29	damaging	0,58	neutral	0,52	neutral	1,51	13,38	0,45	0,55	neutral	0,19	disease	0,52	neutral	0,24	neutral	0,4	2	neutral	0,91	deleterious	0,55	neutral	-6	neutral	0,17	high_impact	2,07	medium_impact	-0,37	medium_impact	0,09	0,84	0,9	0,97	7,02	N	0,52	P	0,55	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6286	6286	T	C	MI.2693	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	383	128	V	A	gTc/gCc	6,14	1	0	possibly_damaging	0,55	deleterious	0	neutral	2,93	neutral	0,28	deleterious	-3,25	medium_impact	2,32	damaging	0,56	neutral	0,61	deleterious	3,21	22,7	0,32	0,55	neutral	0,31	disease	0,57	disease	0,6	disease	0,54	1	deleterious	1	neutral	0,23	deleterious	4	deleterious	0,52	medium_impact	-0,84	low_impact	-1,48	medium_impact	1,04	0,47	0,9	0,97	7,02	P	0,54	P	0,47	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6286	6286	T	A	MI.2694	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	383	128	V	D	gTc/gAc	6,14	1	0	probably_damaging	0,93	deleterious	0	neutral	2,83	deleterious	-3,62	deleterious	-5,58	high_impact	4,74	damaging	0,59	neutral	0,49	deleterious	4,54	24,3	0,07	0,55	disease	0,78	disease	0,84	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,82	low_impact	-1,81	low_impact	-1,48	high_impact	3,28	0,64	0,9	0,97	7,02	P	0,67	P	0,83	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6286	6286	T	G	MI.2695	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	383	128	V	G	gTc/gGc	6,14	1	0	possibly_damaging	0,9	deleterious	0	neutral	2,85	neutral	-1,61	deleterious	-5,73	high_impact	3,69	damaging	0,58	neutral	0,62	deleterious	3,68	23,3	0,12	0,55	disease	0,52	disease	0,7	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,75	low_impact	-1,65	low_impact	-1,48	high_impact	2,31	0,54	0,9	0,97	7,02	P	0,56	P	0,71	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6288	6288	T	C	MI.2696	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	385	129	Y	H	Tac/Cac	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,31	deleterious	-7,29	deleterious	-4,16	high_impact	4,96	neutral	0,6	neutral	0,33	deleterious	3,47	23	0,2	0,55	disease	0,88	disease	0,75	disease	0,85	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,31	0,9	2,92	6,86	P	0,62	P	0,61	polymorphism	0,99	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6288	6288	T	G	MI.2697	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	385	129	Y	D	Tac/Gac	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,3	deleterious	-8,85	deleterious	-8,33	high_impact	5,3	damaging	0,55	neutral	0,37	deleterious	3,83	23,4	0,13	0,55	disease	0,96	disease	0,84	disease	0,85	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,22	0,9	2,92	6,86	P	0,5	N	0,98	polymorphism	0,92	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6288	6288	T	A	MI.2698	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	385	129	Y	N	Tac/Aac	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,31	deleterious	-7,61	deleterious	-7,5	high_impact	4,75	damaging	0,53	neutral	0,43	deleterious	3,91	23,5	0,18	0,55	disease	0,94	disease	0,85	disease	0,75	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,21	0,9	2,92	6,86	P	0,49	N	0,94	polymorphism	0,89	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6289	6289	A	G	MI.2699	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	386	129	Y	C	tAc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,3	deleterious	-9,38	deleterious	-7,5	high_impact	5,3	damaging	0,56	neutral	0,28	deleterious	3,97	23,6	0,2	0,55	disease	0,97	disease	0,85	disease	0,82	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,18	0,9	2,92	6,86	P	0,58	P	0,89	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8537	8537	A	G	MI.27	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	11	4	N	S	aAt/aGt	5,91	1	0,01	benign	0,01	neutral	0,86	neutral	4,64	neutral	0,19	neutral	-2,47	neutral_impact	0,68	neutral	0,83	neutral	0,64	deleterious	2,56	19,88	0,7	0,75	disease	0,6	neutral	0,04	neutral	0,23	neutral	0,33	3	neutral	0,12	deleterious	0,93	neutral	-6	neutral	0,1	medium_impact	1,14	medium_impact	0,74	medium_impact	-0,52	0,22	0,9	41,59	7,51	P	0,57	P	0,33	disease_causing	0,89	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8653	8653	A	C	MI.270	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	127	43	I	L	Atc/Ctc	-8,89	0	0	benign	0,06	neutral	0,7	neutral	4,4	neutral	0,17	neutral	-0,76	neutral_impact	-0,43	neutral	0,87	neutral	0,79	neutral	-0,91	0,03	0,47	0,65	neutral	0,43	neutral	0,18	neutral	0,13	neutral	0,31	4	neutral	0,22	deleterious	0,82	neutral	-6	neutral	0,14	medium_impact	0,38	medium_impact	0,5	low_impact	-1,47	0,59	0,9	31,42	20,88	N	0,44	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6289	6289	A	C	MI.2700	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	386	129	Y	S	tAc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,33	deleterious	-7,72	deleterious	-7,49	high_impact	4,96	neutral	0,65	neutral	0,49	deleterious	4,11	23,8	0,17	0,55	disease	0,92	disease	0,83	disease	0,77	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,3	0,9	2,92	6,86	P	0,65	P	0,9	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6289	6289	A	T	MI.2701	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	386	129	Y	F	tAc/tTc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,35	deleterious	-4,88	deleterious	-3,33	high_impact	4,96	damaging	0,53	neutral	0,35	deleterious	3,89	23,5	0,21	0,55	disease	0,65	disease	0,79	disease	0,73	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,48	0,9	2,92	6,86	P	0,74	P	0,5	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6291	6291	C	G	MI.2702	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	388	130	P	A	Cct/Gct	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-1,89	deleterious	-6,67	high_impact	3,59	neutral	0,65	damaging	0,13	deleterious	2,98	22,2	0,21	0,55	neutral	0,35	disease	0,67	disease	0,58	disease	0,54	1	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	2,22	0,76	0,9	3,31	7,21	N	0,31	N	0,76	polymorphism	0,95	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6291	6291	C	A	MI.2703	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	388	130	P	T	Cct/Act	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	2,65	neutral	-2,52	deleterious	-6,67	medium_impact	3,49	neutral	0,6	damaging	0,09	deleterious	3,76	23,3	0,23	0,55	neutral	0,33	disease	0,83	disease	0,65	disease	0,68	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,12	0,68	0,9	3,31	7,21	N	0,27	N	0,8	polymorphism	0,92	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6291	6291	C	T	MI.2704	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	388	130	P	S	Cct/Tct	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	2,64	neutral	-2,73	deleterious	-6,67	high_impact	4,21	neutral	0,68	damaging	0,11	deleterious	3,77	23,4	0,26	0,55	neutral	0,46	disease	0,8	disease	0,64	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,79	0,34	0,9	3,31	7,21	N	0,33	N	0,85	polymorphism	0,92	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6292	6292	C	T	MI.2705	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	389	130	P	L	cCt/cTt	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,66	neutral	-2,24	deleterious	-8,34	high_impact	4,91	damaging	0,49	damaging	0,11	deleterious	4,23	23,9	0,25	0,55	neutral	0,38	disease	0,84	disease	0,65	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,46	0,9	3,31	7,21	P	0,59	P	0,87	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6292	6292	C	G	MI.2706	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	389	130	P	R	cCt/cGt	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-3,21	deleterious	-7,5	high_impact	5,25	damaging	0,58	damaging	0,08	deleterious	3,54	23,1	0,17	0,55	disease	0,63	disease	0,85	disease	0,78	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,75	0,49	0,9	3,31	7,21	P	0,68	P	0,9	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6292	6292	C	A	MI.2707	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	389	130	P	H	cCt/cAt	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-4,32	deleterious	-7,5	high_impact	5,25	damaging	0,6	damaging	0,07	deleterious	3,85	23,4	0,19	0,55	disease	0,73	disease	0,81	disease	0,75	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,75	0,52	0,9	3,31	7,21	P	0,67	P	0,81	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6294	6294	C	T	MI.2708	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	391	131	P	S	Ccc/Tcc	-20	0	0	probably_damaging	1	deleterious	0	neutral	0,8	deleterious	-6,85	deleterious	-6,67	high_impact	4,76	neutral	0,65	neutral	0,52	deleterious	3,85	23,4	0,26	0,55	disease	0,58	disease	0,8	disease	0,62	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,42	0,9	2,14	6,67	P	0,57	P	0,85	polymorphism	0,93	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6294	6294	C	G	MI.2709	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	391	131	P	A	Ccc/Gcc	-20	0	0	probably_damaging	1	deleterious	0	neutral	0,8	deleterious	-6,95	deleterious	-6,67	high_impact	4,96	neutral	0,7	neutral	0,53	deleterious	3,04	22,4	0,18	0,55	disease	0,65	disease	0,69	disease	0,71	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,63	0,9	2,14	6,67	P	0,6	P	0,76	polymorphism	0,96	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8653	8653	A	T	MI.271	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	127	43	I	F	Atc/Ttc	-8,89	0	0	possibly_damaging	0,56	neutral	0,71	neutral	4,38	neutral	-0,27	neutral	-2,34	low_impact	1,07	neutral	0,9	neutral	0,56	deleterious	2,05	16,5	0,49	0,65	disease	0,74	neutral	0,47	neutral	0,17	disease	0,61	2	neutral	0,48	deleterious	0,58	neutral	-3	deleterious	0,58	medium_impact	-0,86	medium_impact	0,51	medium_impact	-0,18	0,59	0,9	31,42	20,88	N	0,33	N	0,44	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6294	6294	C	A	MI.2710	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	391	131	P	T	Ccc/Acc	-20	0	0	probably_damaging	1	deleterious	0	neutral	0,8	deleterious	-6,98	deleterious	-6,67	high_impact	4,5	neutral	0,65	neutral	0,41	deleterious	3,64	23,2	0,2	0,55	disease	0,74	disease	0,83	disease	0,72	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,66	0,9	2,14	6,67	N	0,41	N	0,8	polymorphism	0,94	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6295	6295	C	A	MI.2711	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	392	131	P	H	cCc/cAc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	0,76	deleterious	-10,06	deleterious	-7,51	high_impact	5,31	neutral	0,65	neutral	0,38	deleterious	3,96	23,6	0,15	0,55	disease	0,91	disease	0,81	disease	0,8	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,61	0,9	2,14	6,67	P	0,61	P	0,81	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6295	6295	C	G	MI.2712	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	392	131	P	R	cCc/cGc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	0,77	deleterious	-8,77	deleterious	-7,51	high_impact	5,31	neutral	0,66	neutral	0,38	deleterious	3,54	23,1	0,16	0,55	disease	0,84	disease	0,85	disease	0,82	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,56	0,9	2,14	6,67	P	0,61	P	0,9	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6295	6295	C	T	MI.2713	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	392	131	P	L	cCc/cTc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	0,78	deleterious	-7,72	deleterious	-8,34	high_impact	5,31	neutral	0,62	neutral	0,44	deleterious	4,33	24	0,21	0,55	neutral	0,39	disease	0,84	disease	0,7	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,77	0,9	2,14	6,67	P	0,55	P	0,87	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6297	6297	T	A	MI.2714	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	394	132	L	M	Tta/Ata	-13,98	0	0	probably_damaging	1	deleterious	0	neutral	1,96	deleterious	-4,27	neutral	-1,67	high_impact	5,3	neutral	0,64	damaging	0,16	deleterious	3,54	23,1	0,28	0,55	disease	0,53	disease	0,55	neutral	0,46	neutral	0,5	0	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,74	0,9	1,36	6,62	P	0,6	P	0,59	polymorphism	0,99	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6297	6297	T	G	MI.2715	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	394	132	L	V	Tta/Gta	-13,98	0	0	probably_damaging	0,99	deleterious	0	neutral	1,97	deleterious	-3,99	deleterious	-2,5	high_impact	4,96	damaging	0,53	damaging	0,11	deleterious	3,37	22,9	0,31	0,55	disease	0,7	disease	0,61	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,64	low_impact	-1,48	high_impact	3,48	0,57	0,9	1,36	6,62	P	0,6	P	0,66	polymorphism	0,98	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6298	6298	T	C	MI.2716	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	395	132	L	S	tTa/tCa	-4,04	0	0	probably_damaging	1	deleterious	0,01	neutral	1,9	deleterious	-5,74	deleterious	-5,01	high_impact	5,3	neutral	0,62	damaging	0,13	deleterious	3,69	23,3	0,24	0,55	disease	0,9	disease	0,77	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,58	medium_impact	-0,92	high_impact	3,8	0,57	0,9	1,36	6,62	P	0,61	P	0,73	polymorphism	0,98	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6298	6298	T	G	MI.2717	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	395	132	L	W	tTa/tGa	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	1,87	deleterious	-7,77	deleterious	-5,01	high_impact	5,3	damaging	0,59	damaging	0,13	deleterious	3,69	23,3	0,15	0,55	disease	0,94	disease	0,67	disease	0,68	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,53	0,9	1,36	6,62	P	0,57	P	0,92	polymorphism	0,97	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6299	6299	A	T	MI.2718	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	396	132	L	F	ttA/ttT	7,53	1	0	probably_damaging	1	deleterious	0	neutral	1,93	deleterious	-4,62	deleterious	-3,34	high_impact	5,3	damaging	0,48	damaging	0,09	deleterious	3,52	23,1	0,3	0,55	disease	0,54	disease	0,73	disease	0,64	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,59	0,9	1,36	6,62	P	0,69	P	0,87	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6299	6299	A	C	MI.2719	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	396	132	L	F	ttA/ttC	7,53	1	0	probably_damaging	1	deleterious	0	neutral	1,93	deleterious	-4,62	deleterious	-3,34	high_impact	5,3	damaging	0,48	damaging	0,09	deleterious	3,41	23	0,3	0,55	disease	0,54	disease	0,73	disease	0,64	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,59	0,9	1,36	6,62	P	0,69	P	0,87	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8653	8653	A	G	MI.272	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	127	43	I	V	Atc/Gtc	-8,89	0	0	benign	0,01	neutral	0,53	neutral	4,41	neutral	0,29	neutral	-0,07	neutral_impact	0,65	neutral	0,98	neutral	0,98	neutral	-0,97	0,02	0,61	0,7	neutral	0,39	neutral	0,12	neutral	0,17	neutral	0,3	4	neutral	0,46	deleterious	0,76	neutral	-6	neutral	0,1	medium_impact	1,14	medium_impact	0,32	medium_impact	-0,54	0,42	0,9	31,42	20,88	N	0,41	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6300	6300	G	C	MI.2720	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	397	133	A	P	Gca/Cca	0,13	0,98	0	possibly_damaging	0,82	deleterious	0	neutral	2,68	neutral	-2,63	neutral	-2,43	medium_impact	2,79	damaging	0,6	neutral	0,32	deleterious	3,68	23,3	0,17	0,55	neutral	0,24	disease	0,83	neutral	0,47	disease	0,73	5	deleterious	1	neutral	0,09	deleterious	4	deleterious	0,72	low_impact	-1,38	low_impact	-1,48	medium_impact	1,48	0,75	0,9	6,24	14,89	N	0,47	N	0,85	disease_causing	0,98	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6300	6300	G	T	MI.2721	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	397	133	A	S	Gca/Tca	0,13	0,98	0	benign	0,02	neutral	1	neutral	2,97	neutral	1,13	neutral	0,92	neutral_impact	-2	neutral	0,66	neutral	0,61	neutral	-1	0,02	0,36	0,55	neutral	0,2	neutral	0,04	neutral	0,1	neutral	0,25	5	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,12	medium_impact	0,83	high_impact	1,86	low_impact	-2,95	0,78	0,9	6,24	14,89	N	0,4	N	0,64	disease_causing	0,84	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6300	6300	G	A	MI.2722	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	397	133	A	T	Gca/Aca	0,13	0,98	0	benign	0,39	deleterious	0,04	neutral	2,79	neutral	-0,2	neutral	-0,94	low_impact	1,04	neutral	0,61	neutral	0,35	deleterious	2,51	19,52	0,41	0,55	neutral	0,29	disease	0,59	neutral	0,31	neutral	0,46	1	neutral	0,95	neutral	0,33	neutral	-2	deleterious	0,49	medium_impact	-0,57	medium_impact	-0,58	medium_impact	-0,14	0,75	0,9	6,24	14,89	N	0,47	N	0,2	disease_causing	0,93	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6301	6301	C	G	MI.2723	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	398	133	A	G	gCa/gGa	3,6	1	0	benign	0,16	deleterious	0	neutral	2,69	neutral	-2,05	neutral	-1,63	medium_impact	3,13	neutral	0,62	neutral	0,49	deleterious	2,05	16,52	0,29	0,55	disease	0,54	disease	0,54	neutral	0,47	disease	0,5	0	deleterious	1	neutral	0,42	deleterious	1	neutral	0,32	medium_impact	-0,08	low_impact	-1,48	medium_impact	1,79	0,75	0,9	6,24	14,89	P	0,52	P	0,56	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6301	6301	C	T	MI.2724	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	398	133	A	V	gCa/gTa	3,6	1	0	benign	0,34	deleterious	0	neutral	2,7	neutral	-1,84	deleterious	-2,7	medium_impact	2,24	neutral	0,6	neutral	0,35	deleterious	2,75	21,1	0,29	0,55	neutral	0,48	disease	0,65	disease	0,51	disease	0,55	1	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,59	medium_impact	-0,49	low_impact	-1,48	medium_impact	0,97	0,8	0,9	6,24	14,89	N	0,44	N	0,75	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6301	6301	C	A	MI.2725	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	398	133	A	E	gCa/gAa	3,6	1	0	possibly_damaging	0,57	deleterious	0	neutral	2,77	neutral	-0,44	neutral	-1,87	medium_impact	3,13	neutral	0,61	neutral	0,38	deleterious	4,16	23,8	0,19	0,55	neutral	0,42	disease	0,8	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,22	deleterious	4	deleterious	0,67	medium_impact	-0,87	low_impact	-1,48	medium_impact	1,79	0,75	0,9	6,24	14,89	N	0,45	N	0,76	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6303	6303	G	C	MI.2726	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	400	134	G	R	Ggg/Cgg	-11,9	0	0	probably_damaging	1	deleterious	0,04	neutral	2,93	neutral	-1,15	neutral	-1,99	medium_impact	2,5	damaging	0,58	damaging	0,07	deleterious	3,92	23,5	0,36	0,55	neutral	0,28	disease	0,8	disease	0,59	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-3,58	medium_impact	-0,58	medium_impact	1,21	0,83	0,9	4,09	7,89	N	0,25	N	0,95	polymorphism	0,96	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6303	6303	G	T	MI.2727	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	400	134	G	W	Ggg/Tgg	-11,9	0	0	probably_damaging	1	deleterious	0	neutral	2,9	neutral	-2,22	deleterious	-3,35	medium_impact	3,06	neutral	0,64	damaging	0,08	deleterious	4,37	24,1	0,21	0,55	disease	0,74	disease	0,8	disease	0,55	disease	0,76	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	medium_impact	1,73	0,47	0,9	4,09	7,89	N	0,23	N	0,83	polymorphism	0,94	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6304	6304	G	C	MI.2728	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	401	134	G	A	gGg/gCg	3,6	1	0	probably_damaging	1	neutral	0,14	neutral	3,04	neutral	0,44	neutral	-0,15	neutral_impact	0,11	neutral	0,66	neutral	0,3	neutral	1,6	13,84	0,52	0,6	neutral	0,15	neutral	0,36	neutral	0,15	neutral	0,45	1	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,68	low_impact	-3,58	medium_impact	-0,25	medium_impact	-1	0,57	0,9	4,09	7,89	P	0,55	P	0,64	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6304	6304	G	A	MI.2729	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	401	134	G	E	gGg/gAg	3,6	1	0	probably_damaging	1	deleterious	0	neutral	2,93	neutral	-1,29	neutral	-1,48	medium_impact	2,5	neutral	0,61	damaging	0,09	deleterious	3,87	23,5	0,41	0,55	neutral	0,21	disease	0,8	disease	0,57	disease	0,75	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	medium_impact	1,21	0,62	0,9	4,09	7,89	N	0,37	N	0,93	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8654	8654	T	G	MI.273	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	128	43	I	S	aTc/aGc	-5,89	0	0	possibly_damaging	0,56	neutral	0,48	neutral	4,44	neutral	0,82	neutral	-2,39	neutral_impact	-0,6	neutral	0,81	neutral	0,76	deleterious	0,61	8,2	0,43	0,65	neutral	0,41	neutral	0,28	neutral	0,22	neutral	0,45	1	neutral	0,56	neutral	0,46	neutral	-3	neutral	0,41	medium_impact	-0,86	medium_impact	0,27	low_impact	-1,61	0,39	0,9	31,42	20,88	N	0,27	N	0,42	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6304	6304	G	T	MI.2730	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	401	134	G	V	gGg/gTg	3,6	1	0	probably_damaging	1	neutral	0,1	neutral	2,99	neutral	-0,13	deleterious	-2,63	low_impact	1,81	damaging	0,57	damaging	0,09	deleterious	3,71	23,3	0,34	0,55	neutral	0,28	disease	0,74	neutral	0,48	disease	0,55	1	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,74	low_impact	-3,58	medium_impact	-0,34	medium_impact	0,57	0,52	0,9	4,09	7,89	N	0,33	N	0,93	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6306	6306	A	G	MI.2731	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	403	135	N	D	Aac/Gac	-9,13	0	0	probably_damaging	0,99	neutral	0,08	neutral	2,77	neutral	-0,65	deleterious	-2,69	medium_impact	3,31	damaging	0,54	damaging	0,06	deleterious	3,79	23,4	0,67	0,7	neutral	0,3	disease	0,51	neutral	0,35	neutral	0,48	0	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,69	low_impact	-2,64	medium_impact	-0,4	medium_impact	1,96	0,43	0,9	1,36	6,64	N	0,33	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6306	6306	A	T	MI.2732	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	403	135	N	Y	Aac/Tac	-9,13	0	0	probably_damaging	1	neutral	0,23	neutral	2,72	neutral	-2,19	deleterious	-4	medium_impact	2,67	damaging	0,53	damaging	0,06	deleterious	3,65	23,2	0,47	0,55	disease	0,62	disease	0,65	neutral	0,21	neutral	0,48	0	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,78	low_impact	-3,58	medium_impact	-0,1	medium_impact	1,37	0,39	0,9	1,36	6,64	N	0,31	N	0,93	polymorphism	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6306	6306	A	C	MI.2733	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	403	135	N	H	Aac/Cac	-9,13	0	0	probably_damaging	1	neutral	0,09	neutral	2,73	neutral	-1,76	deleterious	-2,7	high_impact	3,8	damaging	0,59	damaging	0,06	deleterious	3,04	22,4	0,56	0,6	neutral	0,33	neutral	0,5	neutral	0,38	neutral	0,5	0	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,71	low_impact	-3,58	medium_impact	-0,37	high_impact	2,41	0,38	0,9	1,36	6,64	N	0,36	N	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6307	6307	A	G	MI.2734	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	404	135	N	S	aAc/aGc	8,69	1	0	probably_damaging	0,97	neutral	0,15	neutral	2,89	neutral	0,88	neutral	-2,04	low_impact	1,17	damaging	0,5	damaging	0,09	deleterious	1,86	15,36	0,62	0,65	neutral	0,26	neutral	0,32	neutral	0,2	neutral	0,45	1	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,69	low_impact	-2,18	medium_impact	-0,23	medium_impact	-0,02	0,23	0,9	1,36	6,64	P	0,57	P	0,79	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6307	6307	A	T	MI.2735	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	404	135	N	I	aAc/aTc	8,69	1	0	probably_damaging	1	neutral	0,24	neutral	2,75	neutral	-1,04	deleterious	-4,42	low_impact	1,51	damaging	0,53	damaging	0,09	deleterious	2,75	21,1	0,43	0,55	neutral	0,27	neutral	0,47	neutral	0,2	neutral	0,46	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	-0,09	medium_impact	0,3	0,31	0,9	1,36	6,64	P	0,51	P	0,98	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6307	6307	A	C	MI.2736	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	404	135	N	T	aAc/aCc	8,69	1	0	probably_damaging	0,99	neutral	0,33	neutral	2,8	neutral	-0,12	deleterious	-2,73	medium_impact	2,54	damaging	0,59	damaging	0,1	deleterious	3,27	22,8	0,52	0,6	neutral	0,22	neutral	0,49	neutral	0,31	neutral	0,43	1	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,69	low_impact	-2,64	medium_impact	0,02	medium_impact	1,25	0,46	0,9	1,36	6,64	P	0,5	N	0,59	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6308	6308	C	A	MI.2737	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	405	135	N	K	aaC/aaA	8,69	1	0	probably_damaging	1	neutral	0,11	neutral	2,82	neutral	0,12	deleterious	-3,14	medium_impact	2,88	damaging	0,55	damaging	0,05	deleterious	4,32	24	0,73	0,75	neutral	0,25	neutral	0,45	neutral	0,27	neutral	0,45	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,71	low_impact	-3,58	medium_impact	-0,31	medium_impact	1,56	0,59	0,9	1,36	6,64	P	0,54	P	0,92	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6308	6308	C	G	MI.2738	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	405	135	N	K	aaC/aaG	8,69	1	0	probably_damaging	1	neutral	0,11	neutral	2,82	neutral	0,12	deleterious	-3,14	medium_impact	2,88	damaging	0,55	damaging	0,05	deleterious	3,89	23,5	0,73	0,75	neutral	0,25	neutral	0,45	neutral	0,27	neutral	0,45	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,71	low_impact	-3,58	medium_impact	-0,31	medium_impact	1,56	0,59	0,9	1,36	6,64	P	0,54	P	0,92	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6309	6309	T	G	MI.2739	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	406	136	Y	D	Tac/Gac	-1,26	0	0	benign	0,01	deleterious	0,02	neutral	2,82	neutral	0,78	neutral	-1,57	neutral_impact	-0,94	damaging	0,52	neutral	0,37	deleterious	3,52	23,1	0,41	0,55	neutral	0,2	disease	0,53	neutral	0,39	neutral	0,49	0	neutral	0,98	deleterious	0,51	neutral	-2	neutral	0,15	medium_impact	1,12	medium_impact	-0,75	low_impact	-1,97	0,37	0,9	14,04	52,37	N	0,41	N	0,69	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8654	8654	T	C	MI.274	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	128	43	I	T	aTc/aCc	-5,89	0	0	benign	0,28	neutral	0,44	neutral	4,39	neutral	0	neutral	-1,22	neutral_impact	0,31	neutral	0,94	neutral	0,98	neutral	-0,3	0,65	0,4	0,65	disease	0,58	neutral	0,22	neutral	0,2	neutral	0,49	0	neutral	0,47	deleterious	0,58	neutral	-6	neutral	0,37	medium_impact	-0,37	medium_impact	0,23	medium_impact	-0,83	0,39	0,9	31,42	20,88	N	0,32	N	0,33	polymorphism	1	0,02	rs200811540	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6309	6309	T	A	MI.2740	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	406	136	Y	N	Tac/Aac	-1,26	0	0	benign	0,01	deleterious	0,01	neutral	2,79	neutral	0,48	neutral	-1,37	neutral_impact	0	damaging	0,58	neutral	0,56	deleterious	3,79	23,4	0,46	0,55	neutral	0,18	neutral	0,46	neutral	0,31	neutral	0,47	1	deleterious	0,99	deleterious	0,5	neutral	-2	neutral	0,14	medium_impact	1,12	medium_impact	-0,92	low_impact	-1,1	0,26	0,9	14,04	52,37	N	0,44	N	0,61	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6309	6309	T	C	MI.2741	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	406	136	Y	H	Tac/Cac	-1,26	0	0	benign	0,03	deleterious	0,01	neutral	2,76	neutral	-0,6	neutral	-1,41	low_impact	0,9	damaging	0,59	neutral	0,39	deleterious	3,23	22,8	0,66	0,7	neutral	0,34	neutral	0,29	neutral	0,32	neutral	0,44	1	deleterious	0,99	deleterious	0,49	neutral	-2	neutral	0,18	medium_impact	0,66	medium_impact	-0,92	medium_impact	-0,27	0,2	0,9	14,04	52,37	N	0,45	N	0,45	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6310	6310	A	G	MI.2742	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	407	136	Y	C	tAc/tGc	-0,33	0	0	benign	0,04	deleterious	0,01	neutral	2,75	neutral	-2,34	neutral	-0,09	neutral_impact	0,55	damaging	0,53	neutral	0,36	deleterious	3,26	22,8	0,41	0,55	neutral	0,47	disease	0,57	neutral	0,34	neutral	0,46	1	deleterious	0,99	deleterious	0,49	neutral	-2	neutral	0,21	medium_impact	0,54	medium_impact	-0,92	medium_impact	-0,59	0,12	0,9	14,04	52,37	N	0,44	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6310	6310	A	T	MI.2743	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	407	136	Y	F	tAc/tTc	-0,33	0	0	benign	0	deleterious	0,02	neutral	2,79	neutral	-0,38	neutral	0,66	neutral_impact	-0,8	neutral	0,64	neutral	0,69	neutral	1,4	12,81	0,43	0,55	neutral	0,3	neutral	0,33	neutral	0,28	neutral	0,45	1	neutral	0,98	deleterious	0,51	neutral	-2	neutral	0,13	high_impact	2,07	medium_impact	-0,75	low_impact	-1,84	0,2	0,9	14,04	52,37	N	0,46	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6310	6310	A	C	MI.2744	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	407	136	Y	S	tAc/tCc	-0,33	0	0	benign	0	deleterious	0,01	neutral	2,85	neutral	1,08	neutral	-0,58	neutral_impact	-1,59	damaging	0,54	neutral	0,54	deleterious	1,82	15,09	0,29	0,55	neutral	0,17	neutral	0,36	neutral	0,22	neutral	0,44	1	deleterious	0,99	deleterious	0,51	neutral	-2	neutral	0,13	high_impact	2,07	medium_impact	-0,92	low_impact	-2,57	0,29	0,9	14,04	52,37	N	0,48	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6312	6312	T	C	MI.2745	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	409	137	S	P	Tcc/Ccc	-7,28	0	0	possibly_damaging	0,74	deleterious	0,02	neutral	2,94	neutral	-1,57	neutral	-2,01	medium_impact	2,38	damaging	0,54	neutral	0,3	deleterious	3,85	23,4	0,24	0,55	disease	0,52	disease	0,77	neutral	0,44	disease	0,56	1	deleterious	0,98	neutral	0,14	deleterious	4	deleterious	0,56	low_impact	-1,18	medium_impact	-0,75	medium_impact	1,1	0,54	0,9	13,84	61,64	N	0,31	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6312	6312	T	A	MI.2746	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	409	137	S	T	Tcc/Acc	-7,28	0	0	benign	0,34	neutral	0,05	neutral	2,97	neutral	-0,64	neutral	-1,09	low_impact	1,78	neutral	0,69	neutral	0,64	deleterious	2,19	17,42	0,3	0,55	neutral	0,19	neutral	0,34	neutral	0,42	neutral	0,44	1	neutral	0,94	neutral	0,36	neutral	-6	neutral	0,24	medium_impact	-0,49	medium_impact	-0,52	medium_impact	0,55	0,71	0,9	13,84	61,64	N	0,5	N	0,08	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6312	6312	T	G	MI.2747	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	409	137	S	A	Tcc/Gcc	-7,28	0	0	benign	0,01	neutral	1	neutral	3,16	neutral	1,61	neutral	1,28	neutral_impact	-0,74	neutral	0,74	neutral	0,92	neutral	-0,85	0,03	0,41	0,55	neutral	0,17	neutral	0,04	neutral	0,19	neutral	0,21	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,1	medium_impact	1,12	high_impact	1,86	low_impact	-1,78	0,66	0,9	13,84	61,64	N	0,42	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6313	6313	C	G	MI.2748	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	410	137	S	C	tCc/tGc	6,14	1	0	probably_damaging	0,92	deleterious	0,01	neutral	2,93	neutral	-2,53	neutral	-1,49	high_impact	3,58	damaging	0,48	damaging	0,24	deleterious	3,5	23,1	0,3	0,55	disease	0,69	disease	0,63	neutral	0,45	neutral	0,47	1	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,69	low_impact	-1,76	medium_impact	-0,92	high_impact	2,21	0,62	0,9	13,84	61,64	P	0,56	P	0,37	disease_causing	0,84	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6313	6313	C	T	MI.2749	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	410	137	S	F	tCc/tTc	6,14	1	0	possibly_damaging	0,9	neutral	0,16	neutral	3,04	neutral	0,51	neutral	-2,28	neutral_impact	0,66	damaging	0,5	damaging	0,24	deleterious	2,37	18,61	0,24	0,55	neutral	0,17	disease	0,6	neutral	0,3	neutral	0,42	2	neutral	0,95	neutral	0,13	neutral	-3	deleterious	0,61	low_impact	-1,65	medium_impact	-0,21	medium_impact	-0,49	0,31	0,9	13,84	61,64	P	0,55	P	0,71	disease_causing	0,94	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8654	8654	T	A	MI.275	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	128	43	I	N	aTc/aAc	-5,89	0	0	possibly_damaging	0,85	neutral	0,35	neutral	4,39	neutral	0,02	deleterious	-3,44	neutral_impact	0,66	neutral	0,85	neutral	0,44	deleterious	3,19	22,7	0,42	0,65	neutral	0,38	disease	0,59	neutral	0,22	neutral	0,43	1	neutral	0,87	neutral	0,25	neutral	-3	deleterious	0,63	low_impact	-1,47	medium_impact	0,14	medium_impact	-0,53	0,36	0,9	31,42	20,88	N	0,31	N	0,46	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6313	6313	C	A	MI.2750	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	410	137	S	Y	tCc/tAc	6,14	1	0	possibly_damaging	0,9	neutral	0,11	neutral	3,05	neutral	0,67	neutral	-2,37	low_impact	0,93	damaging	0,51	neutral	0,28	deleterious	2,07	16,65	0,29	0,55	neutral	0,31	disease	0,56	neutral	0,27	neutral	0,44	1	neutral	0,96	neutral	0,11	neutral	-3	deleterious	0,65	low_impact	-1,65	medium_impact	-0,31	medium_impact	-0,24	0,62	0,9	13,84	61,64	P	0,57	P	0,75	disease_causing	0,9	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6315	6315	C	G	MI.2751	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	412	138	H	D	Cac/Gac	-5,42	0	0	probably_damaging	1	deleterious	0	neutral	2,82	neutral	-1,91	deleterious	-7,52	high_impact	4,41	neutral	0,62	damaging	0,09	deleterious	3,83	23,4	0,34	0,55	neutral	0,41	disease	0,82	disease	0,82	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,97	0,46	0,9	2,73	6,86	N	0,48	N	0,97	polymorphism	0,86	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6315	6315	C	A	MI.2752	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	412	138	H	N	Cac/Aac	-5,42	0	0	probably_damaging	1	deleterious	0	neutral	2,84	neutral	-1,64	deleterious	-5,85	high_impact	4,13	damaging	0,57	damaging	0,09	deleterious	3,9	23,5	0,64	0,7	neutral	0,41	disease	0,81	disease	0,79	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,42	0,9	2,73	6,86	N	0,4	N	0,86	polymorphism	0,95	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6315	6315	C	T	MI.2753	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	412	138	H	Y	Cac/Tac	-5,42	0	0	probably_damaging	1	deleterious	0	neutral	2,79	neutral	-2,71	deleterious	-4,87	high_impact	3,52	neutral	0,62	damaging	0,08	deleterious	3,72	23,3	0,61	0,65	neutral	0,42	disease	0,81	disease	0,79	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,15	0,25	0,9	2,73	6,86	N	0,37	N	0,72	polymorphism	0,94	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6316	6316	A	T	MI.2754	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	413	138	H	L	cAc/cTc	5,45	1	0	probably_damaging	1	deleterious	0,03	neutral	2,8	neutral	-2,59	deleterious	-9,13	high_impact	3,86	neutral	0,63	damaging	0,08	deleterious	4,33	24	0,32	0,55	neutral	0,41	disease	0,88	disease	0,78	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,79	low_impact	-3,58	medium_impact	-0,65	high_impact	2,47	0,32	0,9	2,73	6,86	P	0,57	P	0,92	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6316	6316	A	G	MI.2755	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	413	138	H	R	cAc/cGc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,8	neutral	-2,48	deleterious	-6,68	high_impact	5,11	damaging	0,55	damaging	0,12	deleterious	3,48	23,1	0,57	0,6	neutral	0,39	disease	0,83	disease	0,78	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,3	0,9	2,73	6,86	P	0,66	P	0,85	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6316	6316	A	C	MI.2756	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	413	138	H	P	cAc/cCc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,8	neutral	-2,41	deleterious	-8,35	high_impact	4,75	damaging	0,55	damaging	0,1	deleterious	3,69	23,3	0,28	0,55	disease	0,59	disease	0,85	disease	0,78	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,31	0,9	2,73	6,86	P	0,65	P	0,9	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6317	6317	C	G	MI.2757	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	414	138	H	Q	caC/caG	8,69	1	0	probably_damaging	1	neutral	0,06	neutral	2,82	neutral	-1,94	deleterious	-6,66	medium_impact	2,88	damaging	0,59	damaging	0,12	deleterious	3,55	23,1	0,65	0,7	neutral	0,16	disease	0,74	disease	0,74	disease	0,56	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,71	low_impact	-3,58	medium_impact	-0,47	medium_impact	1,56	0,35	0,9	2,73	6,86	N	0,43	N	0,83	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6317	6317	C	A	MI.2758	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	414	138	H	Q	caC/caA	8,69	1	0	probably_damaging	1	neutral	0,06	neutral	2,82	neutral	-1,94	deleterious	-6,66	medium_impact	2,88	damaging	0,59	damaging	0,12	deleterious	3,83	23,4	0,65	0,7	neutral	0,16	disease	0,74	disease	0,74	disease	0,56	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,71	low_impact	-3,58	medium_impact	-0,47	medium_impact	1,56	0,35	0,9	2,73	6,86	N	0,44	N	0,83	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6318	6318	C	T	MI.2759	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	415	139	P	S	Cct/Tct	-1,95	0	0	possibly_damaging	0,57	neutral	0,74	neutral	3,04	neutral	-1,51	neutral	2,12	neutral_impact	-1,43	neutral	0,68	neutral	0,82	neutral	1,37	12,62	0,33	0,55	neutral	0,19	neutral	0,08	neutral	0,16	neutral	0,24	5	neutral	0,48	deleterious	0,59	neutral	-3	neutral	0,34	medium_impact	-0,87	medium_impact	0,45	low_impact	-2,42	0,27	0,9	13,45	64,38	N	0,36	N	0,35	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8655	8655	C	G	MI.276	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	129	43	I	M	atC/atG	-0,1	0	0	possibly_damaging	0,74	neutral	0,23	neutral	4,37	neutral	-0,67	neutral	-1,06	low_impact	1,2	neutral	0,91	neutral	0,73	neutral	1,73	14,55	0,56	0,65	disease	0,73	neutral	0,23	neutral	0,16	disease	0,55	1	neutral	0,84	neutral	0,25	neutral	-3	deleterious	0,56	low_impact	-1,19	medium_impact	-0,01	medium_impact	-0,07	0,68	0,9	31,42	20,88	N	0,52	P	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6318	6318	C	A	MI.2760	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	415	139	P	T	Cct/Act	-1,95	0	0	possibly_damaging	0,57	deleterious	0,02	neutral	2,92	neutral	-1,94	neutral	0,83	low_impact	1,7	neutral	0,64	neutral	0,78	deleterious	3,71	23,3	0,26	0,55	neutral	0,23	neutral	0,23	neutral	0,27	neutral	0,43	1	neutral	0,98	neutral	0,23	deleterious	1	neutral	0,35	medium_impact	-0,87	medium_impact	-0,75	medium_impact	0,47	0,58	0,9	13,45	64,38	P	0,51	P	0,27	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6318	6318	C	G	MI.2761	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	415	139	P	A	Cct/Gct	-1,95	0	0	benign	0,04	neutral	1	neutral	2,95	neutral	-1,65	neutral	2,03	neutral_impact	-0,34	neutral	0,76	neutral	0,99	deleterious	0,26	5,28	0,28	0,55	neutral	0,17	neutral	0,08	neutral	0,27	neutral	0,28	4	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,09	medium_impact	0,54	high_impact	1,86	low_impact	-1,41	0,68	0,9	13,45	64,38	N	0,32	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6319	6319	C	T	MI.2762	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	416	139	P	L	cCt/cTt	5,22	1	0	possibly_damaging	0,57	neutral	0,07	neutral	3,04	neutral	-2,17	neutral	-0,84	low_impact	1,67	neutral	0,63	neutral	0,57	deleterious	4,22	23,9	0,29	0,55	neutral	0,26	neutral	0,39	neutral	0,5	neutral	0,43	1	neutral	0,93	neutral	0,25	neutral	-3	neutral	0,38	medium_impact	-0,87	medium_impact	-0,43	medium_impact	0,44	0,68	0,9	13,45	64,38	P	0,63	P	0,58	disease_causing	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6319	6319	C	A	MI.2763	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	416	139	P	H	cCt/cAt	5,22	1	0	probably_damaging	0,97	deleterious	0	neutral	2,88	deleterious	-3,28	neutral	-0,52	low_impact	1,76	neutral	0,61	neutral	0,48	deleterious	3,89	23,5	0,31	0,55	neutral	0,43	neutral	0,35	disease	0,58	neutral	0,48	1	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,65	low_impact	-2,18	low_impact	-1,48	medium_impact	0,53	0,63	0,9	13,45	64,38	P	0,54	P	0,63	polymorphism	0,87	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6319	6319	C	G	MI.2764	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	416	139	P	R	cCt/cGt	5,22	1	0	probably_damaging	0,91	deleterious	0	neutral	2,89	neutral	-2,69	neutral	-0,22	medium_impact	2,77	damaging	0,56	neutral	0,48	deleterious	3,54	23,1	0,3	0,55	neutral	0,28	disease	0,55	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,6	low_impact	-1,7	low_impact	-1,48	medium_impact	1,46	0,63	0,9	13,45	64,38	P	0,49	N	0,58	polymorphism	0,78	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6321	6321	G	C	MI.2765	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	418	140	G	R	Gga/Cga	-5,66	0	0	probably_damaging	1	deleterious	0,02	neutral	2,66	deleterious	-3,23	deleterious	-6,23	high_impact	5,1	damaging	0,44	damaging	0,02	deleterious	3,9	23,5	0,26	0,55	disease	0,57	disease	0,86	disease	0,76	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,58	medium_impact	-0,75	high_impact	3,61	0,8	0,9	3,51	6,71	P	0,55	P	0,95	polymorphism	0,78	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6321	6321	G	T	MI.2766	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	418	140	G	W	Gga/Tga	-5,66	0	0	probably_damaging	1	deleterious	0	neutral	2,64	deleterious	-4	deleterious	-6,42	high_impact	5,1	damaging	0,4	damaging	0,03	deleterious	4,37	24,1	0,19	0,55	disease	0,93	disease	0,86	disease	0,76	disease	0,64	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,61	0,42	0,9	3,51	6,71	P	0,58	P	0,83	polymorphism	0,68	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6322	6322	G	C	MI.2767	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	419	140	G	A	gGa/gCa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-2,9	deleterious	-4,71	high_impact	4,41	damaging	0,57	damaging	0,05	deleterious	3,02	22,3	0,33	0,55	disease	0,52	disease	0,66	disease	0,66	disease	0,64	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,97	0,72	0,9	3,51	6,71	P	0,5	N	0,64	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6322	6322	G	T	MI.2768	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	419	140	G	V	gGa/gTa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-3,09	deleterious	-7,14	high_impact	5,1	damaging	0,48	damaging	0,03	deleterious	3,67	23,3	0,23	0,55	disease	0,68	disease	0,86	disease	0,72	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,61	0,55	0,9	3,51	6,71	P	0,66	P	0,93	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6322	6322	G	A	MI.2769	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	419	140	G	E	gGa/gAa	7,3	1	0	probably_damaging	1	neutral	0,05	neutral	2,76	neutral	-1,55	deleterious	-6,15	high_impact	4,75	damaging	0,39	damaging	0,03	deleterious	3,75	23,3	0,38	0,55	neutral	0,45	disease	0,85	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,82	low_impact	-3,58	medium_impact	-0,52	high_impact	3,29	0,61	0,9	3,51	6,71	P	0,74	P	0,93	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8655	8655	C	A	MI.277	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	129	43	I	M	atC/atA	-0,1	0	0	possibly_damaging	0,74	neutral	0,23	neutral	4,37	neutral	-0,67	neutral	-1,06	low_impact	1,2	neutral	0,91	neutral	0,73	deleterious	2,15	17,16	0,56	0,65	disease	0,73	neutral	0,23	neutral	0,16	disease	0,55	1	neutral	0,84	neutral	0,25	neutral	-3	deleterious	0,56	low_impact	-1,19	medium_impact	-0,01	medium_impact	-0,07	0,68	0,9	31,42	20,88	N	0,52	P	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6324	6324	G	C	MI.2770	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	421	141	A	P	Gcc/Ccc	-3,34	0	0	benign	0,06	neutral	0,39	neutral	2,99	neutral	-0,11	neutral	-1,16	neutral_impact	-0,36	neutral	0,7	neutral	0,61	deleterious	2,09	16,8	0,18	0,55	neutral	0,24	neutral	0,4	neutral	0,14	neutral	0,45	1	neutral	0,57	deleterious	0,67	neutral	-6	neutral	0,18	medium_impact	0,37	medium_impact	0,09	low_impact	-1,43	0,66	0,9	7,6	10,17	N	0,48	N	0,85	disease_causing	0,91	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6324	6324	G	A	MI.2771	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	421	141	A	T	Gcc/Acc	-3,34	0	0	possibly_damaging	0,63	deleterious	0,04	neutral	2,96	neutral	-0,56	neutral	-1,23	medium_impact	2,09	neutral	0,65	neutral	0,48	deleterious	4,09	23,7	0,34	0,55	neutral	0,27	disease	0,53	neutral	0,35	neutral	0,4	2	neutral	0,96	neutral	0,21	deleterious	4	deleterious	0,52	medium_impact	-0,97	medium_impact	-0,58	medium_impact	0,83	0,68	0,9	7,6	10,17	N	0,44	N	0,2	disease_causing	0,75	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6324	6324	G	T	MI.2772	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	421	141	A	S	Gcc/Tcc	-3,34	0	0	possibly_damaging	0,5	neutral	0,51	neutral	2,95	neutral	-0,69	neutral	-0,28	neutral_impact	0,36	neutral	0,66	neutral	0,61	deleterious	2,24	17,79	0,24	0,55	neutral	0,34	neutral	0,34	neutral	0,18	neutral	0,47	1	neutral	0,49	deleterious	0,51	neutral	-3	neutral	0,36	medium_impact	-0,76	medium_impact	0,2	medium_impact	-0,77	0,68	0,9	7,6	10,17	N	0,44	N	0,64	disease_causing	0,57	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6325	6325	C	G	MI.2773	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	422	141	A	G	gCc/gGc	4,06	1	0	benign	0,34	neutral	0,3	neutral	2,93	neutral	-1,27	neutral	-1,2	neutral_impact	0,62	neutral	0,65	neutral	0,61	deleterious	2,43	19	0,2	0,55	neutral	0,24	neutral	0,36	neutral	0,17	neutral	0,45	1	neutral	0,64	deleterious	0,48	neutral	-6	neutral	0,27	medium_impact	-0,49	medium_impact	-0,01	medium_impact	-0,53	0,59	0,9	7,6	10,17	P	0,57	P	0,56	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6325	6325	C	T	MI.2774	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	422	141	A	V	gCc/gTc	4,06	1	0	possibly_damaging	0,66	deleterious	0,02	neutral	3,06	neutral	0,58	neutral	-1,86	low_impact	0,92	neutral	0,64	neutral	0,4	deleterious	3,29	22,8	0,26	0,55	neutral	0,21	disease	0,58	neutral	0,23	neutral	0,27	5	deleterious	0,98	neutral	0,18	deleterious	1	deleterious	0,58	low_impact	-1,03	medium_impact	-0,75	medium_impact	-0,25	0,57	0,9	7,6	10,17	P	0,53	P	0,75	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6325	6325	C	A	MI.2775	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	422	141	A	D	gCc/gAc	4,06	1	0	probably_damaging	0,98	deleterious	0,01	neutral	2,91	neutral	-2,08	neutral	-2,23	high_impact	3,67	neutral	0,61	neutral	0,35	deleterious	4,58	24,4	0,2	0,55	disease	0,56	disease	0,83	neutral	0,48	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,78	low_impact	-2,35	medium_impact	-0,92	high_impact	2,29	0,51	0,9	7,6	10,17	N	0,47	N	0,89	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6327	6327	T	G	MI.2776	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	424	142	S	A	Tcc/Gcc	-8,2	0	0	probably_damaging	0,99	deleterious	0,04	neutral	2,94	neutral	-0,53	neutral	-2,06	low_impact	1,86	damaging	0,47	damaging	0,22	deleterious	2,49	19,43	0,36	0,55	neutral	0,25	neutral	0,32	disease	0,56	neutral	0,4	2	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,69	low_impact	-2,64	medium_impact	-0,58	medium_impact	0,62	0,71	0,9	1,95	6,61	N	0,42	N	0,35	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6327	6327	T	A	MI.2777	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	424	142	S	T	Tcc/Acc	-8,2	0	0	probably_damaging	0,99	deleterious	0,03	neutral	2,85	neutral	-2,05	neutral	-2,33	high_impact	3,7	damaging	0,41	damaging	0,11	deleterious	3,76	23,3	0,26	0,55	disease	0,57	disease	0,69	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,76	low_impact	-2,64	medium_impact	-0,65	high_impact	2,32	0,75	0,9	1,95	6,61	N	0,47	N	0,43	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6327	6327	T	C	MI.2778	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	424	142	S	P	Tcc/Ccc	-8,2	0	0	probably_damaging	1	deleterious	0	neutral	2,9	neutral	-1,05	deleterious	-3,9	high_impact	4,18	damaging	0,3	damaging	0,1	deleterious	3,91	23,5	0,23	0,55	disease	0,76	disease	0,83	disease	0,85	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,76	0,57	0,9	1,95	6,61	P	0,62	P	0,91	polymorphism	0,98	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6328	6328	C	T	MI.2779	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	425	142	S	F	tCc/tTc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,85	neutral	-1,84	deleterious	-4,74	high_impact	4,99	damaging	0,23	damaging	0,05	deleterious	4,19	23,9	0,17	0,55	disease	0,81	disease	0,88	disease	0,78	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,51	0,34	0,9	1,95	6,61	P	0,9	P	0,98	disease_causing_automatic	1	0,18	rs267606883	Pathogenic	Cytochrome_c_oxidase_i_deficiency	RCV000010309.4	MedGen	.	.	.	.	C6328T	EXIT (Exercise Intolerance)	+	-	Reported	2
chrM	8656	8656	A	G	MI.278	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	130	44	T	A	Acc/Gcc	-10,51	0	0	benign	0	neutral	0,48	neutral	4,36	neutral	-0,45	neutral	-2,25	low_impact	1,29	neutral	0,92	neutral	0,94	deleterious	0,13	3,93	0,67	0,75	neutral	0,41	neutral	0,37	neutral	0,3	neutral	0,47	1	neutral	0,51	deleterious	0,74	neutral	-6	neutral	0,17	high_impact	2,09	medium_impact	0,27	medium_impact	0,01	0,63	0,9	21,24	19,09	N	0,41	N	0,24	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6328	6328	C	G	MI.2780	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	425	142	S	C	tCc/tGc	7,53	1	0	probably_damaging	1	deleterious	0,03	neutral	2,82	deleterious	-3,41	deleterious	-3,63	medium_impact	2,73	damaging	0,37	damaging	0,09	deleterious	3,47	23	0,25	0,55	disease	0,83	disease	0,78	disease	0,7	disease	0,59	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,82	low_impact	-3,58	medium_impact	-0,65	medium_impact	1,42	0,62	0,9	1,95	6,61	P	0,63	P	0,85	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6328	6328	C	A	MI.2781	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	425	142	S	Y	tCc/tAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,9	neutral	-1,08	deleterious	-4,73	high_impact	4,64	damaging	0,39	damaging	0,08	deleterious	3,99	23,6	0,19	0,55	disease	0,83	disease	0,86	disease	0,78	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,19	0,64	0,9	1,95	6,61	P	0,76	P	0,92	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6330	6330	G	C	MI.2782	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	427	143	V	L	Gta/Cta	-11,44	0	0	probably_damaging	0,97	neutral	0,05	neutral	2,8	neutral	-0,8	neutral	-2,2	high_impact	3,57	neutral	0,62	damaging	0,13	deleterious	3,52	23,1	0,42	0,55	disease	0,51	disease	0,75	disease	0,51	disease	0,55	1	deleterious	0,99	neutral	0,04	deleterious	2	deleterious	0,78	low_impact	-2,18	medium_impact	-0,52	high_impact	2,2	0,87	0,9	4,29	7,21	N	0,31	N	0,55	polymorphism	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6330	6330	G	T	MI.2783	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	427	143	V	L	Gta/Tta	-11,44	0	0	probably_damaging	0,97	neutral	0,05	neutral	2,8	neutral	-0,8	neutral	-2,2	high_impact	3,57	neutral	0,62	damaging	0,13	deleterious	3,63	23,2	0,42	0,55	disease	0,51	disease	0,75	disease	0,51	disease	0,55	1	deleterious	0,99	neutral	0,04	deleterious	2	deleterious	0,78	low_impact	-2,18	medium_impact	-0,52	high_impact	2,2	0,87	0,9	4,29	7,21	N	0,31	N	0,55	polymorphism	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6330	6330	G	A	MI.2784	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	427	143	V	M	Gta/Ata	-11,44	0	0	probably_damaging	1	neutral	0,05	neutral	2,7	neutral	-1,55	neutral	-2,11	medium_impact	2,1	damaging	0,56	damaging	0,18	deleterious	3,63	23,2	0,39	0,55	disease	0,68	disease	0,64	neutral	0,3	neutral	0,22	6	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,77	low_impact	-3,58	medium_impact	-0,52	medium_impact	0,84	0,8	0,9	4,29	7,21	N	0,33	N	0,82	polymorphism	0,98	0,05	.	.	.	.	.	.	COSM1145863	.	.	.	.	.	.	.	.
chrM	6331	6331	T	A	MI.2785	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	428	143	V	E	gTa/gAa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-3,67	deleterious	-4,89	high_impact	5,07	neutral	0,61	damaging	0,16	deleterious	4,57	24,4	0,12	0,55	neutral	0,39	disease	0,87	disease	0,8	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,58	0,55	0,9	4,29	7,21	P	0,71	P	0,84	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6331	6331	T	G	MI.2786	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	428	143	V	G	gTa/gGa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,68	deleterious	-3,19	deleterious	-5,74	medium_impact	3,34	damaging	0,6	damaging	0,17	deleterious	3,75	23,3	0,16	0,55	neutral	0,49	disease	0,79	disease	0,69	disease	0,66	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	medium_impact	1,99	0,58	0,9	4,29	7,21	N	0,45	N	0,71	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6331	6331	T	C	MI.2787	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	428	143	V	A	gTa/gCa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,77	neutral	-1,76	deleterious	-3,26	medium_impact	3,48	neutral	0,67	damaging	0,16	deleterious	3,5	23,1	0,38	0,55	neutral	0,44	disease	0,62	disease	0,67	disease	0,65	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,11	0,43	0,9	4,29	7,21	P	0,53	P	0,47	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6333	6333	G	C	MI.2788	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	430	144	D	H	Gac/Cac	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	2,37	deleterious	-4,92	deleterious	-5,88	high_impact	4,91	damaging	0,45	damaging	0,07	deleterious	3,54	23,1	0,27	0,55	disease	0,72	disease	0,86	disease	0,81	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,64	0,9	3,9	7,8	P	0,6	P	0,97	disease_causing	0,9	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6333	6333	G	A	MI.2789	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	430	144	D	N	Gac/Aac	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-3,1	deleterious	-4,2	high_impact	3,52	damaging	0,4	damaging	0,1	deleterious	4,13	23,8	0,51	0,6	neutral	0,45	disease	0,8	disease	0,64	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,15	0,86	0,9	3,9	7,8	N	0,42	N	0,89	disease_causing	0,63	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8656	8656	A	C	MI.279	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	130	44	T	P	Acc/Ccc	-10,51	0	0	benign	0,35	neutral	0,09	neutral	4,3	neutral	-2,61	deleterious	-3,67	medium_impact	3,5	neutral	0,72	neutral	0,44	neutral	1,63	14,02	0,13	0,65	disease	0,76	disease	0,87	disease	0,71	disease	0,79	6	neutral	0,89	neutral	0,37	neutral	-3	deleterious	0,49	medium_impact	-0,5	medium_impact	-0,28	medium_impact	1,9	0,7	0,9	21,24	19,09	N	0,37	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6333	6333	G	T	MI.2790	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	430	144	D	Y	Gac/Tac	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	2,36	deleterious	-5,62	deleterious	-7,56	high_impact	4,45	damaging	0,48	damaging	0,06	deleterious	3,84	23,4	0,2	0,55	disease	0,74	disease	0,93	disease	0,77	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,01	0,52	0,9	3,9	7,8	N	0,42	N	0,94	disease_causing	0,95	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6334	6334	A	G	MI.2791	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	431	144	D	G	gAc/gGc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,44	neutral	-2,98	deleterious	-5,89	high_impact	3,87	damaging	0,46	damaging	0,08	deleterious	3,86	23,5	0,26	0,55	disease	0,67	disease	0,85	disease	0,71	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,47	0,59	0,9	3,9	7,8	P	0,55	P	0,85	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6334	6334	A	T	MI.2792	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	431	144	D	V	gAc/gTc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,36	deleterious	-5,25	deleterious	-7,57	high_impact	4,45	damaging	0,47	damaging	0,07	deleterious	3,64	23,2	0,19	0,55	disease	0,51	disease	0,91	disease	0,74	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,01	0,4	0,9	3,9	7,8	P	0,5	N	0,93	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6334	6334	A	C	MI.2793	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	431	144	D	A	gAc/gCc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,43	deleterious	-3,18	deleterious	-6,73	high_impact	4,36	damaging	0,58	damaging	0,09	deleterious	3,55	23,1	0,24	0,55	neutral	0,49	disease	0,8	disease	0,74	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,93	0,66	0,9	3,9	7,8	P	0,51	P	0,85	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6335	6335	C	G	MI.2794	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	432	144	D	E	gaC/gaG	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,44	deleterious	-3,08	deleterious	-3,36	high_impact	3,73	damaging	0,44	damaging	0,07	deleterious	3,84	23,4	0,44	0,55	neutral	0,48	disease	0,79	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,64	low_impact	-1,48	high_impact	2,35	0,72	0,9	3,9	7,8	P	0,6	P	0,65	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6335	6335	C	A	MI.2795	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	432	144	D	E	gaC/gaA	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,44	deleterious	-3,08	deleterious	-3,36	high_impact	3,73	damaging	0,44	damaging	0,07	deleterious	4,18	23,8	0,44	0,55	neutral	0,48	disease	0,79	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,64	low_impact	-1,48	high_impact	2,35	0,72	0,9	3,9	7,8	P	0,61	P	0,65	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6336	6336	C	G	MI.2796	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	433	145	L	V	Cta/Gta	-2,88	0	0	benign	0,38	deleterious	0	neutral	2,63	neutral	-1,47	neutral	-2,02	high_impact	3,51	damaging	0,48	damaging	0,1	deleterious	3,33	22,9	0,29	0,55	neutral	0,35	disease	0,62	neutral	0,39	neutral	0,46	1	deleterious	1	neutral	0,31	deleterious	2	neutral	0,36	medium_impact	-0,56	low_impact	-1,48	high_impact	2,14	0,7	0,9	3,31	8,22	N	0,38	N	0,66	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6336	6336	C	A	MI.2797	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	433	145	L	M	Cta/Ata	-2,88	0	0	benign	0,38	neutral	0,11	neutral	2,6	neutral	-1,97	neutral	-1,04	low_impact	1,66	damaging	0,52	damaging	0,24	deleterious	2,69	20,8	0,27	0,55	neutral	0,45	neutral	0,31	neutral	0,19	neutral	0,46	1	neutral	0,87	neutral	0,37	neutral	-6	neutral	0,3	medium_impact	-0,56	medium_impact	-0,31	medium_impact	0,43	0,7	0,9	3,31	8,22	N	0,5	N	0,59	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6337	6337	T	G	MI.2798	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	434	145	L	R	cTa/cGa	-2,19	0	0	probably_damaging	0,99	deleterious	0	neutral	2,53	deleterious	-4,21	deleterious	-4,41	high_impact	4,96	damaging	0,5	damaging	0,08	deleterious	4,1	23,7	0,08	0,55	disease	0,72	disease	0,87	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,64	low_impact	-1,48	high_impact	3,48	0,6	0,9	3,31	8,22	P	0,6	P	0,9	polymorphism	0,98	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6337	6337	T	A	MI.2799	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	434	145	L	Q	cTa/cAa	-2,19	0	0	probably_damaging	0,99	deleterious	0	neutral	2,51	deleterious	-3,68	deleterious	-4,33	high_impact	4,96	damaging	0,51	damaging	0,11	deleterious	4,04	23,7	0,11	0,55	disease	0,73	disease	0,8	disease	0,54	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,64	low_impact	-1,48	high_impact	3,48	0,7	0,9	3,31	8,22	P	0,61	P	0,82	polymorphism	0,98	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8538	8538	T	A	MI.28	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	12	4	N	K	aaT/aaA	1,75	0,93	0	benign	0,07	deleterious	0	neutral	4,49	neutral	-0,72	deleterious	-3,89	medium_impact	2,85	neutral	0,87	neutral	0,35	deleterious	4,65	24,5	0,63	0,7	disease	0,6	disease	0,52	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,47	deleterious	1	neutral	0,33	medium_impact	0,31	low_impact	-1,4	medium_impact	1,35	0,28	0,9	41,59	7,51	N	0,47	N	0,94	disease_causing	0,69	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8656	8656	A	T	MI.280	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	130	44	T	S	Acc/Tcc	-10,51	0	0	benign	0,09	neutral	0,9	neutral	4,5	neutral	0,99	neutral	-0,95	neutral_impact	0,43	neutral	0,86	neutral	0,91	neutral	-0,67	0,08	0,46	0,65	neutral	0,36	neutral	0,26	neutral	0,23	neutral	0,45	1	neutral	0,03	deleterious	0,91	neutral	-6	neutral	0,18	medium_impact	0,2	medium_impact	0,83	medium_impact	-0,73	0,8	0,9	21,24	19,09	N	0,33	N	0,05	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6337	6337	T	C	MI.2800	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	434	145	L	P	cTa/cCa	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-4,49	deleterious	-5,22	high_impact	4,41	damaging	0,43	damaging	0,09	deleterious	3,84	23,4	0,11	0,55	disease	0,79	disease	0,82	disease	0,67	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,97	0,5	0,9	3,31	8,22	N	0,42	N	0,83	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6339	6339	A	T	MI.2801	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	436	146	T	S	Acc/Tcc	-1,26	0	0	benign	0,24	neutral	0,12	neutral	2,78	neutral	-0,51	neutral	0,02	neutral_impact	0,76	neutral	0,7	neutral	0,68	deleterious	0,19	4,54	0,47	0,55	neutral	0,36	neutral	0,35	neutral	0,16	neutral	0,47	1	neutral	0,86	neutral	0,44	neutral	-6	neutral	0,28	medium_impact	-0,29	medium_impact	-0,29	medium_impact	-0,4	0,78	0,9	16,76	29,59	P	0,59	P	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6339	6339	A	G	MI.2802	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	436	146	T	A	Acc/Gcc	-1,26	0	0	benign	0,14	neutral	1	neutral	2,89	neutral	1,07	neutral	1,34	neutral_impact	-0,56	neutral	0,77	neutral	0,87	neutral	-1,23	0,01	0,5	0,6	neutral	0,19	neutral	0,06	neutral	0,16	neutral	0,24	5	neutral	0,14	deleterious	0,93	neutral	-6	neutral	0,17	medium_impact	-0,01	high_impact	1,86	low_impact	-1,62	0,44	0,9	16,76	29,59	N	0,36	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6339	6339	A	C	MI.2803	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	436	146	T	P	Acc/Ccc	-1,26	0	0	possibly_damaging	0,77	deleterious	0,02	neutral	2,75	neutral	-1,7	neutral	-1,89	high_impact	3,83	neutral	0,63	neutral	0,35	deleterious	3,06	22,4	0,13	0,55	disease	0,59	disease	0,81	disease	0,58	disease	0,74	5	deleterious	0,99	neutral	0,13	deleterious	5	deleterious	0,73	low_impact	-1,25	medium_impact	-0,75	high_impact	2,44	0,64	0,9	16,76	29,59	N	0,4	N	0,67	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6340	6340	C	G	MI.2804	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	437	146	T	S	aCc/aGc	0,82	0,01	0	benign	0,24	neutral	0,12	neutral	2,78	neutral	-0,51	neutral	0,02	neutral_impact	0,76	neutral	0,7	neutral	0,68	deleterious	0,37	6,35	0,47	0,55	neutral	0,36	neutral	0,35	neutral	0,16	neutral	0,47	1	neutral	0,86	neutral	0,44	neutral	-6	neutral	0,28	medium_impact	-0,29	medium_impact	-0,29	medium_impact	-0,4	0,78	0,9	16,76	29,59	P	0,59	P	0,15	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6340	6340	C	T	MI.2805	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	437	146	T	I	aCc/aTc	0,82	0,01	0	benign	0,18	deleterious	0	neutral	2,84	neutral	0,56	neutral	-1,85	medium_impact	2,29	neutral	0,74	neutral	0,56	deleterious	1,9	15,59	0,27	0,55	neutral	0,21	disease	0,68	neutral	0,43	disease	0,5	0	deleterious	1	neutral	0,41	deleterious	1	neutral	0,18	medium_impact	-0,14	low_impact	-1,48	medium_impact	1,02	0,71	0,9	16,76	29,59	N	0,51	P	0,47	polymorphism	1	0,04	.	.	.	.	.	.	.	.	0,45	C6340T	Prostate Cancer	+	-	Reported	2
chrM	6340	6340	C	A	MI.2806	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	437	146	T	N	aCc/aAc	0,82	0,01	0	possibly_damaging	0,83	deleterious	0,01	neutral	2,74	neutral	-2,1	neutral	-2,1	medium_impact	3,48	neutral	0,63	neutral	0,47	deleterious	3,43	23	0,32	0,55	disease	0,54	disease	0,68	neutral	0,45	neutral	0,49	0	deleterious	0,99	neutral	0,09	deleterious	4	deleterious	0,69	low_impact	-1,4	medium_impact	-0,92	high_impact	2,11	0,76	0,9	16,76	29,59	N	0,39	N	0,53	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6342	6342	A	C	MI.2807	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	439	147	I	L	Atc/Ctc	-14,22	0	0	benign	0,18	deleterious	0	neutral	2,74	neutral	0,18	neutral	-1,74	high_impact	3,7	neutral	0,62	damaging	0,13	deleterious	3,72	23,3	0,34	0,55	neutral	0,3	disease	0,58	disease	0,57	disease	0,62	2	deleterious	1	neutral	0,41	deleterious	2	neutral	0,22	medium_impact	-0,14	low_impact	-1,48	high_impact	2,32	0,75	0,9	5,46	8,09	N	0,37	N	0,61	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6342	6342	A	T	MI.2808	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	439	147	I	F	Atc/Ttc	-14,22	0	0	possibly_damaging	0,8	deleterious	0	neutral	2,63	neutral	-2,64	deleterious	-3,47	high_impact	4,45	damaging	0,53	damaging	0,1	deleterious	3,78	23,4	0,23	0,55	disease	0,72	disease	0,77	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	5	deleterious	0,73	low_impact	-1,32	low_impact	-1,48	high_impact	3,01	0,83	0,9	5,46	8,09	N	0,4	N	0,85	polymorphism	0,58	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6342	6342	A	G	MI.2809	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	439	147	I	V	Atc/Gtc	-14,22	0	0	benign	0,1	deleterious	0,04	neutral	2,68	neutral	-0,79	neutral	-0,87	high_impact	3,52	neutral	0,6	damaging	0,15	deleterious	2,96	22,1	0,48	0,55	neutral	0,19	neutral	0,44	disease	0,59	neutral	0,43	1	neutral	0,96	deleterious	0,47	deleterious	2	neutral	0,17	medium_impact	0,14	medium_impact	-0,58	high_impact	2,15	0,66	0,9	5,46	8,09	N	0,41	N	0,23	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8657	8657	C	T	MI.281	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	131	44	T	I	aCc/aTc	-3,11	0	0	benign	0	neutral	0,61	neutral	4,41	neutral	0,27	deleterious	-3,54	low_impact	1,31	neutral	0,92	neutral	0,86	deleterious	1,86	15,34	0,38	0,65	neutral	0,49	disease	0,64	neutral	0,35	neutral	0,5	0	neutral	0,38	deleterious	0,81	neutral	-6	neutral	0,21	high_impact	2,09	medium_impact	0,4	medium_impact	0,03	0,76	0,9	21,24	19,09	N	0,25	N	0,14	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6343	6343	T	C	MI.2810	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	440	147	I	T	aTc/aCc	6,84	1	0	probably_damaging	0,9	deleterious	0	neutral	2,62	neutral	-2,16	deleterious	-4,34	high_impact	4,36	damaging	0,54	damaging	0,17	deleterious	3,29	22,8	0,28	0,55	neutral	0,48	disease	0,69	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,6	low_impact	-1,65	low_impact	-1,48	high_impact	2,93	0,7	0,9	5,46	8,09	P	0,5	N	0,76	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6343	6343	T	A	MI.2811	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	440	147	I	N	aTc/aAc	6,84	1	0	probably_damaging	0,94	deleterious	0	neutral	2,59	deleterious	-3,99	deleterious	-6,08	high_impact	5,25	damaging	0,56	damaging	0,13	deleterious	4,29	24	0,19	0,55	disease	0,85	disease	0,79	disease	0,69	disease	0,65	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,81	low_impact	-1,88	low_impact	-1,48	high_impact	3,75	0,7	0,9	5,46	8,09	P	0,65	P	0,94	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6343	6343	T	G	MI.2812	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	440	147	I	S	aTc/aGc	6,84	1	0	possibly_damaging	0,44	deleterious	0	neutral	2,6	neutral	-2,86	deleterious	-5,21	high_impact	5,25	neutral	0,68	damaging	0,19	deleterious	4,19	23,9	0,19	0,55	disease	0,74	disease	0,82	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,28	deleterious	5	neutral	0,4	medium_impact	-0,66	low_impact	-1,48	high_impact	3,75	0,52	0,9	5,46	8,09	P	0,65	P	0,62	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6344	6344	C	G	MI.2813	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	441	147	I	M	atC/atG	7,53	1	0	probably_damaging	0,93	neutral	0,06	neutral	2,62	neutral	-2,45	deleterious	-2,6	high_impact	3,68	neutral	0,69	damaging	0,15	deleterious	3,28	22,8	0,27	0,55	disease	0,7	disease	0,6	disease	0,69	disease	0,65	3	deleterious	0,98	neutral	0,07	deleterious	2	deleterious	0,69	low_impact	-1,81	medium_impact	-0,47	high_impact	2,3	0,84	0,9	5,46	8,09	P	0,53	P	0,76	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6344	6344	C	A	MI.2814	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	441	147	I	M	atC/atA	7,53	1	0	probably_damaging	0,93	neutral	0,06	neutral	2,62	neutral	-2,45	deleterious	-2,6	high_impact	3,68	neutral	0,69	damaging	0,15	deleterious	3,71	23,3	0,27	0,55	disease	0,7	disease	0,6	disease	0,69	disease	0,65	3	deleterious	0,98	neutral	0,07	deleterious	2	deleterious	0,69	low_impact	-1,81	medium_impact	-0,47	high_impact	2,3	0,84	0,9	5,46	8,09	P	0,53	P	0,76	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6345	6345	T	C	MI.2815	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	442	148	F	L	Ttc/Ctc	-2,42	0	0	probably_damaging	1	neutral	0,11	neutral	2,99	neutral	1,21	deleterious	-5,2	medium_impact	2,43	damaging	0,37	neutral	0,58	deleterious	3,95	23,6	0,41	0,55	neutral	0,17	disease	0,57	neutral	0,49	neutral	0,16	7	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,68	low_impact	-3,58	medium_impact	-0,31	medium_impact	1,15	0,85	0,9	1,36	7,62	P	0,64	P	0,83	disease_causing	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6345	6345	T	G	MI.2816	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	442	148	F	V	Ttc/Gtc	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	2,85	neutral	0,38	deleterious	-6,07	high_impact	3,6	damaging	0,51	neutral	0,42	deleterious	3,97	23,6	0,19	0,55	neutral	0,28	disease	0,8	disease	0,65	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,71	low_impact	-3,58	low_impact	-1,48	high_impact	2,23	0,76	0,9	1,36	7,62	N	0,4	N	0,84	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6345	6345	T	A	MI.2817	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	442	148	F	I	Ttc/Atc	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	2,84	neutral	0,26	deleterious	-5,2	high_impact	3,75	damaging	0,58	neutral	0,56	deleterious	4,29	24	0,19	0,55	neutral	0,22	disease	0,73	disease	0,63	disease	0,53	1	deleterious	1	neutral	0	deleterious	6	deleterious	0,71	low_impact	-3,58	low_impact	-1,48	high_impact	2,36	0,73	0,9	1,36	7,62	N	0,4	N	0,88	disease_causing	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6346	6346	T	C	MI.2818	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	443	148	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-1,59	deleterious	-6,94	high_impact	4,27	neutral	0,64	neutral	0,52	deleterious	4,11	23,7	0,13	0,55	neutral	0,2	disease	0,8	disease	0,69	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	high_impact	2,84	0,7	0,9	1,36	7,62	P	0,5	N	0,84	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6346	6346	T	G	MI.2819	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	443	148	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,66	deleterious	-3,28	deleterious	-6,94	high_impact	4,82	damaging	0,55	neutral	0,45	deleterious	4	23,6	0,15	0,55	disease	0,65	disease	0,79	disease	0,71	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,35	0,5	0,9	1,36	7,62	P	0,66	P	0,91	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8657	8657	C	G	MI.282	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	131	44	T	S	aCc/aGc	-3,11	0	0	benign	0,09	neutral	0,9	neutral	4,5	neutral	0,99	neutral	-0,95	neutral_impact	0,43	neutral	0,86	neutral	0,91	neutral	-0,48	0,25	0,46	0,65	neutral	0,36	neutral	0,26	neutral	0,23	neutral	0,45	1	neutral	0,03	deleterious	0,91	neutral	-6	neutral	0,18	medium_impact	0,2	medium_impact	0,83	medium_impact	-0,73	0,8	0,9	21,24	19,09	N	0,28	N	0,05	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6346	6346	T	A	MI.2820	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	443	148	F	Y	tTc/tAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,68	neutral	-2,47	deleterious	-2,6	high_impact	4,12	damaging	0,57	neutral	0,43	deleterious	4,14	23,8	0,21	0,55	disease	0,53	disease	0,69	disease	0,7	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,78	0,9	1,36	7,62	P	0,59	P	0,59	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6347	6347	C	A	MI.2821	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	444	148	F	L	ttC/ttA	7,53	1	0	probably_damaging	1	neutral	0,11	neutral	2,99	neutral	1,21	deleterious	-5,2	medium_impact	2,43	damaging	0,37	neutral	0,58	deleterious	4,53	24,3	0,41	0,55	neutral	0,17	disease	0,57	neutral	0,49	neutral	0,16	7	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,68	low_impact	-3,58	medium_impact	-0,31	medium_impact	1,15	0,85	0,9	1,36	7,62	P	0,75	P	0,83	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6347	6347	C	G	MI.2822	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	444	148	F	L	ttC/ttG	7,53	1	0	probably_damaging	1	neutral	0,11	neutral	2,99	neutral	1,21	deleterious	-5,2	medium_impact	2,43	damaging	0,37	neutral	0,58	deleterious	4,28	24	0,41	0,55	neutral	0,17	disease	0,57	neutral	0,49	neutral	0,16	7	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,68	low_impact	-3,58	medium_impact	-0,31	medium_impact	1,15	0,85	0,9	1,36	7,62	P	0,75	P	0,83	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6348	6348	T	G	MI.2823	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	445	149	S	A	Tcc/Gcc	-1,49	0	0	probably_damaging	0,99	deleterious	0,04	neutral	2,84	neutral	-0,93	neutral	-2,48	medium_impact	2,76	damaging	0,54	neutral	0,57	deleterious	3,48	23,1	0,27	0,55	neutral	0,28	disease	0,5	neutral	0,43	neutral	0,37	3	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,7	low_impact	-2,64	medium_impact	-0,58	medium_impact	1,45	0,65	0,9	1,56	6,75	N	0,44	N	0,35	polymorphism	0,92	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6348	6348	T	C	MI.2824	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	445	149	S	P	Tcc/Ccc	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,68	deleterious	-3,75	deleterious	-4,29	high_impact	5,17	damaging	0,34	neutral	0,6	deleterious	3,8	23,4	0,13	0,55	disease	0,75	disease	0,82	disease	0,74	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,64	0,9	1,56	6,75	P	0,79	P	0,91	disease_causing	0,66	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6348	6348	T	A	MI.2825	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	445	149	S	T	Tcc/Acc	-1,49	0	0	probably_damaging	0,97	deleterious	0	neutral	2,7	deleterious	-3	deleterious	-2,56	high_impact	4,28	damaging	0,46	neutral	0,53	deleterious	3,61	23,2	0,21	0,55	disease	0,54	disease	0,64	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,75	low_impact	-2,18	low_impact	-1,48	high_impact	2,85	0,77	0,9	1,56	6,75	P	0,51	P	0,43	polymorphism	0,77	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6349	6349	C	G	MI.2826	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	446	149	S	C	tCc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,66	deleterious	-4,95	deleterious	-4,26	high_impact	5,17	damaging	0,44	neutral	0,48	deleterious	3,49	23,1	0,14	0,55	disease	0,81	disease	0,79	disease	0,61	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,68	0,9	1,56	6,75	P	0,72	P	0,85	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6349	6349	C	T	MI.2827	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	446	149	S	F	tCc/tTc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-2,83	deleterious	-5,15	high_impact	4,62	damaging	0,37	neutral	0,52	deleterious	4,18	23,8	0,11	0,55	disease	0,74	disease	0,89	disease	0,6	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,17	0,51	0,9	1,56	6,75	P	0,75	P	0,98	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6349	6349	C	A	MI.2828	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	446	149	S	Y	tCc/tAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,68	deleterious	-3,69	deleterious	-5,15	high_impact	5,17	damaging	0,45	neutral	0,46	deleterious	4	23,6	0,1	0,55	disease	0,78	disease	0,86	disease	0,65	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,69	0,9	1,56	6,75	P	0,71	P	0,92	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6351	6351	T	A	MI.2829	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	448	150	L	M	Tta/Ata	-10,98	0	0	probably_damaging	1	deleterious	0	neutral	2,43	neutral	-2,38	neutral	-1,73	high_impact	3,88	damaging	0,57	damaging	0,08	deleterious	3,51	23,1	0,28	0,55	disease	0,56	disease	0,62	disease	0,54	disease	0,63	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	2,48	0,72	0,9	1,36	6,64	N	0,29	N	0,59	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8657	8657	C	A	MI.283	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	131	44	T	N	aCc/aAc	-3,11	0	0	benign	0,35	neutral	0,22	neutral	4,47	neutral	0,75	deleterious	-2,59	medium_impact	2,15	neutral	0,8	neutral	0,68	deleterious	1,84	15,22	0,48	0,65	neutral	0,35	disease	0,76	neutral	0,31	disease	0,57	1	neutral	0,74	neutral	0,44	neutral	-3	neutral	0,43	medium_impact	-0,5	medium_impact	-0,02	medium_impact	0,75	0,8	0,9	21,24	19,09	N	0,33	N	0,59	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6351	6351	T	G	MI.2830	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	448	150	L	V	Tta/Gta	-10,98	0	0	probably_damaging	0,99	deleterious	0	neutral	2,64	neutral	-1,53	deleterious	-2,6	high_impact	3,66	damaging	0,53	damaging	0,07	deleterious	3,31	22,9	0,33	0,55	neutral	0,33	disease	0,66	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-2,64	low_impact	-1,48	high_impact	2,28	0,61	0,9	1,36	6,64	N	0,28	N	0,66	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6352	6352	T	C	MI.2831	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	449	150	L	S	tTa/tCa	-0,1	0	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-3,77	deleterious	-5,2	high_impact	4,92	damaging	0,55	damaging	0,07	deleterious	3,63	23,2	0,18	0,55	disease	0,65	disease	0,81	disease	0,65	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,63	0,9	1,36	6,64	P	0,59	P	0,73	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6352	6352	T	G	MI.2832	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	449	150	L	W	tTa/tGa	-0,1	0	0	probably_damaging	1	deleterious	0	neutral	2,38	deleterious	-4,18	deleterious	-5,21	high_impact	4,92	damaging	0,52	damaging	0,05	deleterious	3,67	23,3	0,1	0,55	disease	0,89	disease	0,76	disease	0,58	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,43	0,9	1,36	6,64	P	0,55	P	0,92	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6353	6353	A	C	MI.2833	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	450	150	L	F	ttA/ttC	4,76	0,72	0	probably_damaging	1	deleterious	0	neutral	2,43	deleterious	-3,45	deleterious	-3,47	high_impact	4,58	damaging	0,52	damaging	0,05	deleterious	3,35	22,9	0,32	0,55	disease	0,65	disease	0,77	disease	0,57	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,13	0,63	0,9	1,36	6,64	N	0,43	N	0,87	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6353	6353	A	T	MI.2834	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	450	150	L	F	ttA/ttT	4,76	0,72	0	probably_damaging	1	deleterious	0	neutral	2,43	deleterious	-3,45	deleterious	-3,47	high_impact	4,58	damaging	0,52	damaging	0,05	deleterious	3,43	23	0,32	0,55	disease	0,65	disease	0,77	disease	0,57	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,13	0,63	0,9	1,36	6,64	N	0,45	N	0,87	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6354	6354	C	T	MI.2835	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	451	151	H	Y	Cac/Tac	-14,68	0	0	probably_damaging	0,99	deleterious	0	neutral	2,78	neutral	-2,48	deleterious	-5,21	high_impact	4,43	damaging	0,49	damaging	0,02	deleterious	3,58	23,2	0,43	0,55	disease	0,53	disease	0,84	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,64	low_impact	-1,48	high_impact	2,99	0,6	0,9	3,7	6,68	N	0,39	N	0,72	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6354	6354	C	A	MI.2836	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	451	151	H	N	Cac/Aac	-14,68	0	0	probably_damaging	0,99	deleterious	0	neutral	2,76	deleterious	-3,4	deleterious	-6,08	high_impact	5,24	damaging	0,49	damaging	0,02	deleterious	3,76	23,3	0,41	0,55	disease	0,54	disease	0,78	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	3,74	0,61	0,9	3,7	6,68	N	0,54	P	0,86	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6354	6354	C	G	MI.2837	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	451	151	H	D	Cac/Gac	-14,68	0	0	probably_damaging	1	deleterious	0	neutral	2,75	deleterious	-3,83	deleterious	-7,81	high_impact	5,24	damaging	0,45	damaging	0,02	deleterious	3,75	23,3	0,22	0,55	disease	0,6	disease	0,84	disease	0,79	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,55	0,9	3,7	6,68	N	0,49	N	0,97	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6355	6355	A	G	MI.2838	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	452	151	H	R	cAc/cGc	5,68	1	0	probably_damaging	0,99	deleterious	0	neutral	2,78	neutral	-2,59	deleterious	-6,95	high_impact	5,24	damaging	0,52	damaging	0,02	deleterious	2,77	21,2	0,43	0,55	disease	0,51	disease	0,84	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,64	low_impact	-1,48	high_impact	3,74	0,44	0,9	3,7	6,68	P	0,65	P	0,85	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6355	6355	A	T	MI.2839	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	452	151	H	L	cAc/cTc	5,68	1	0	probably_damaging	0,99	deleterious	0	neutral	2,9	neutral	-0,68	deleterious	-9,55	high_impact	3,69	damaging	0,58	damaging	0,03	deleterious	3,6	23,2	0,22	0,55	neutral	0,27	disease	0,88	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	high_impact	2,31	0,37	0,9	3,7	6,68	N	0,48	N	0,92	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8659	8659	A	T	MI.284	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	133	45	T	S	Acc/Tcc	-20	0	0,01	benign	0,14	neutral	0,13	neutral	4,43	neutral	0,63	neutral	-1,29	neutral_impact	-0,21	neutral	0,9	neutral	0,74	deleterious	1,85	15,31	0,47	0,65	neutral	0,41	neutral	0,26	disease	0,53	neutral	0,47	1	neutral	0,85	deleterious	0,5	neutral	-6	neutral	0,22	medium_impact	-0,01	medium_impact	-0,18	low_impact	-1,28	0,7	0,9	18,14	18,2	N	0,41	N	0,2	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6355	6355	A	C	MI.2840	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	452	151	H	P	cAc/cCc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,76	deleterious	-3,28	deleterious	-8,68	high_impact	5,24	damaging	0,42	damaging	0,03	deleterious	3,05	22,4	0,24	0,55	disease	0,65	disease	0,86	disease	0,81	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,47	0,9	3,7	6,68	P	0,69	P	0,9	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6356	6356	C	A	MI.2841	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	453	151	H	Q	caC/caA	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,8	neutral	-2,09	deleterious	-6,95	high_impact	4,43	damaging	0,57	damaging	0,02	deleterious	3,82	23,4	0,46	0,55	neutral	0,27	disease	0,79	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-2,64	low_impact	-1,48	high_impact	2,99	0,52	0,9	3,7	6,68	N	0,43	N	0,83	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6356	6356	C	G	MI.2842	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	453	151	H	Q	caC/caG	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,8	neutral	-2,09	deleterious	-6,95	high_impact	4,43	damaging	0,57	damaging	0,02	deleterious	3,48	23,1	0,46	0,55	neutral	0,27	disease	0,79	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-2,64	low_impact	-1,48	high_impact	2,99	0,52	0,9	3,7	6,68	N	0,43	N	0,83	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6357	6357	C	G	MI.2843	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	454	152	L	V	Cta/Gta	-1,49	0	0	probably_damaging	0,99	deleterious	0,01	neutral	2,56	neutral	-1,2	neutral	-2,32	medium_impact	3,04	damaging	0,36	neutral	0,29	deleterious	3,26	22,8	0,4	0,55	neutral	0,28	disease	0,63	neutral	0,36	neutral	0,2	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,72	low_impact	-2,64	medium_impact	-0,92	medium_impact	1,71	0,68	0,9	1,95	6,79	P	0,55	P	0,66	polymorphism	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6357	6357	C	A	MI.2844	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	454	152	L	M	Cta/Ata	-1,49	0	0	probably_damaging	1	deleterious	0,03	neutral	2,37	deleterious	-3,56	neutral	-1,41	medium_impact	2,19	damaging	0,4	neutral	0,55	deleterious	3,73	23,3	0,31	0,55	disease	0,55	neutral	0,44	neutral	0,32	disease	0,53	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,73	low_impact	-3,58	medium_impact	-0,65	medium_impact	0,92	0,71	0,9	1,95	6,79	P	0,6	P	0,59	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6358	6358	T	C	MI.2845	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	455	152	L	P	cTa/cCa	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	2,34	deleterious	-5,43	deleterious	-5,82	high_impact	5	damaging	0,33	damaging	0,26	deleterious	3,8	23,4	0,17	0,55	neutral	0,48	disease	0,87	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,7	0,9	1,95	6,79	P	0,6	P	0,83	disease_causing	0,6	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6358	6358	T	G	MI.2846	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	455	152	L	R	cTa/cGa	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	2,35	deleterious	-4,88	deleterious	-4,99	high_impact	5	damaging	0,41	damaging	0,23	deleterious	4,07	23,7	0,13	0,55	disease	0,69	disease	0,91	disease	0,7	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,54	0,9	1,95	6,79	P	0,63	P	0,9	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6358	6358	T	A	MI.2847	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	455	152	L	Q	cTa/cAa	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	2,34	deleterious	-5,05	deleterious	-4,93	high_impact	5	damaging	0,42	neutral	0,3	deleterious	3,99	23,6	0,15	0,55	disease	0,71	disease	0,84	disease	0,58	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,72	0,9	1,95	6,79	P	0,62	P	0,82	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6360	6360	G	C	MI.2848	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	457	153	A	P	Gca/Cca	-4,5	0	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-3,73	deleterious	-4,21	high_impact	4,8	damaging	0,51	damaging	0,04	deleterious	3,72	23,3	0,11	0,55	disease	0,67	disease	0,91	disease	0,72	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,33	0,78	0,9	2,92	6,73	P	0,63	P	0,85	polymorphism	0,77	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6360	6360	G	T	MI.2849	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	457	153	A	S	Gca/Tca	-4,5	0	0	probably_damaging	1	deleterious	0,03	neutral	2,77	neutral	-0,34	neutral	-2,35	medium_impact	2,75	neutral	0,6	damaging	0,05	deleterious	3,54	23,1	0,46	0,55	neutral	0,21	disease	0,76	neutral	0,33	neutral	0,19	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,65	medium_impact	1,44	0,9	0,95	2,92	6,73	N	0,28	N	0,64	polymorphism	0,96	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8659	8659	A	G	MI.285	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	133	45	T	A	Acc/Gcc	-20	0	0,01	benign	0,01	neutral	0,19	neutral	4,49	neutral	1,34	neutral	-0,59	neutral_impact	-0,5	neutral	0,93	neutral	0,87	deleterious	1,87	15,39	0,61	0,7	neutral	0,42	neutral	0,2	neutral	0,29	neutral	0,38	2	neutral	0,81	deleterious	0,59	neutral	-6	neutral	0,16	medium_impact	1,14	medium_impact	-0,06	low_impact	-1,53	0,52	0,9	18,14	18,2	N	0,44	N	0,22	polymorphism	1	0,01	rs879150284	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6360	6360	G	A	MI.2850	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	457	153	A	T	Gca/Aca	-4,5	0	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-1,35	deleterious	-3,28	high_impact	3,6	damaging	0,6	damaging	0,06	deleterious	4,12	23,8	0,54	0,6	neutral	0,19	disease	0,79	neutral	0,38	neutral	0,19	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	high_impact	2,23	0,78	0,9	2,92	6,73	N	0,3	N	0,2	polymorphism	0,92	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6361	6361	C	A	MI.2851	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	458	153	A	E	gCa/gAa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,64	deleterious	-3,15	deleterious	-4,17	high_impact	5,14	damaging	0,58	damaging	0,06	deleterious	4,4	24,1	0,18	0,55	disease	0,51	disease	0,92	disease	0,69	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,65	0,73	0,9	2,92	6,73	P	0,69	P	0,76	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6361	6361	C	G	MI.2852	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	458	153	A	G	gCa/gGa	7,53	1	0	probably_damaging	1	deleterious	0,03	neutral	2,66	neutral	-2,17	deleterious	-3,35	high_impact	3,65	neutral	0,61	damaging	0,05	deleterious	3,82	23,4	0,36	0,55	disease	0,59	disease	0,82	neutral	0,5	neutral	0,47	1	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,77	low_impact	-3,58	medium_impact	-0,65	high_impact	2,27	0,81	0,9	2,92	6,73	N	0,44	N	0,56	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6361	6361	C	T	MI.2853	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	458	153	A	V	gCa/gTa	7,53	1	0	probably_damaging	1	deleterious	0,04	neutral	2,89	neutral	0,59	deleterious	-3,42	high_impact	3,95	damaging	0,58	damaging	0,04	deleterious	4,3	24	0,41	0,55	neutral	0,32	disease	0,88	disease	0,58	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,77	low_impact	-3,58	medium_impact	-0,58	high_impact	2,55	0,75	0,9	2,92	6,73	P	0,5	N	0,75	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6363	6363	G	C	MI.2854	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	460	154	G	R	Ggt/Cgt	-9,82	0	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-3,61	deleterious	-6,95	high_impact	5,31	damaging	0,56	damaging	0,07	deleterious	3,89	23,5	0,14	0,55	disease	0,8	disease	0,91	disease	0,8	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,77	0,9	1,75	6,74	P	0,61	P	0,95	polymorphism	0,7	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6363	6363	G	A	MI.2855	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	460	154	G	S	Ggt/Agt	-9,82	0	0	probably_damaging	1	deleterious	0	neutral	2,65	neutral	-2,78	deleterious	-5,21	high_impact	4,42	neutral	0,64	damaging	0,1	deleterious	4,06	23,7	0,25	0,55	disease	0,57	disease	0,86	disease	0,65	disease	0,58	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,98	0,59	0,9	1,75	6,74	N	0,43	N	0,73	polymorphism	0,83	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6363	6363	G	T	MI.2856	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	460	154	G	C	Ggt/Tgt	-9,82	0	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-4,62	deleterious	-7,83	high_impact	4,96	damaging	0,54	damaging	0,09	deleterious	4,05	23,7	0,14	0,55	disease	0,92	disease	0,92	disease	0,69	disease	0,64	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,67	0,9	1,75	6,74	P	0,54	P	0,98	polymorphism	0,55	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6364	6364	G	T	MI.2857	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	461	154	G	V	gGt/gTt	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,79	neutral	-1,11	deleterious	-7,82	high_impact	4,96	damaging	0,49	damaging	0,1	deleterious	3,67	23,2	0,13	0,55	disease	0,77	disease	0,91	disease	0,71	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,65	0,9	1,75	6,74	P	0,67	P	0,93	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6364	6364	G	C	MI.2858	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	461	154	G	A	gGt/gCt	9,15	1	0	probably_damaging	1	deleterious	0,01	neutral	2,68	neutral	-2,29	deleterious	-5,21	high_impact	5,31	neutral	0,7	damaging	0,14	deleterious	3	22,2	0,23	0,55	disease	0,66	disease	0,74	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,58	medium_impact	-0,92	high_impact	3,8	0,67	0,9	1,75	6,74	P	0,71	P	0,64	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6364	6364	G	A	MI.2859	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	461	154	G	D	gGt/gAt	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-3,74	deleterious	-6,08	high_impact	4,96	damaging	0,54	damaging	0,08	deleterious	3,67	23,3	0,15	0,55	disease	0,72	disease	0,92	disease	0,78	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,49	0,9	1,75	6,74	P	0,69	P	0,97	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8659	8659	A	C	MI.286	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	133	45	T	P	Acc/Ccc	-20	0	0,01	possibly_damaging	0,48	deleterious	0,01	neutral	4,34	neutral	-1,92	neutral	-2,32	neutral_impact	0,67	neutral	0,8	neutral	0,42	deleterious	3,52	23,1	0,14	0,65	disease	0,78	disease	0,77	disease	0,67	disease	0,79	6	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,66	medium_impact	-0,72	medium_impact	-0,84	medium_impact	-0,52	0,64	0,9	18,14	18,2	N	0,29	N	0,35	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6366	6366	G	C	MI.2860	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	463	155	V	L	Gtc/Ctc	-20	0	0,01	benign	0,01	neutral	0,19	neutral	2,62	neutral	-1,73	neutral	-1,11	low_impact	1,74	neutral	0,87	neutral	0,54	neutral	1,5	13,3	0,55	0,6	neutral	0,2	disease	0,66	neutral	0,32	neutral	0,23	5	neutral	0,81	deleterious	0,59	neutral	-6	neutral	0,13	medium_impact	1,12	medium_impact	-0,16	medium_impact	0,51	0,79	0,9	12,48	34,19	N	0,38	N	0,24	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6366	6366	G	T	MI.2861	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	463	155	V	F	Gtc/Ttc	-20	0	0,01	possibly_damaging	0,53	deleterious	0	neutral	2,47	deleterious	-3,85	deleterious	-2,59	medium_impact	2,21	neutral	0,68	neutral	0,49	deleterious	2,1	16,83	0,19	0,55	neutral	0,25	disease	0,88	neutral	0,5	disease	0,55	1	deleterious	1	neutral	0,24	deleterious	4	deleterious	0,5	medium_impact	-0,81	low_impact	-1,48	medium_impact	0,94	0,62	0,9	12,48	34,19	N	0,38	N	0,77	polymorphism	0,93	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6366	6366	G	A	MI.2862	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	463	155	V	I	Gtc/Atc	-20	0	0,01	benign	0	neutral	1	neutral	2,77	neutral	-0,83	neutral	-0,1	neutral_impact	-0,44	neutral	0,8	neutral	0,97	neutral	-1,16	0,01	0,53	0,6	neutral	0,17	neutral	0,11	neutral	0,22	neutral	0,27	5	neutral	0	deleterious	1	neutral	-6	neutral	0,07	high_impact	2,07	high_impact	1,86	low_impact	-1,51	0,72	0,9	12,48	34,19	N	0,32	N	0	polymorphism	1	0,01	rs370673798	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6367	6367	T	C	MI.2863	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	464	155	V	A	gTc/gCc	0,36	0,13	0	benign	0,26	neutral	0,23	neutral	2,63	neutral	-1,68	neutral	-1,25	neutral_impact	0,16	neutral	0,75	neutral	0,74	neutral	-0,33	0,58	0,46	0,55	neutral	0,31	neutral	0,25	neutral	0,33	neutral	0,43	1	neutral	0,72	deleterious	0,49	neutral	-6	neutral	0,23	medium_impact	-0,33	medium_impact	-0,1	medium_impact	-0,95	0,56	0,9	12,48	34,19	N	0,51	P	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6367	6367	T	A	MI.2864	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	464	155	V	D	gTc/gAc	0,36	0,13	0	possibly_damaging	0,74	deleterious	0	neutral	2,42	deleterious	-7,08	deleterious	-4,23	high_impact	3,96	neutral	0,7	neutral	0,39	deleterious	4,06	23,7	0,11	0,55	disease	0,81	disease	0,88	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,75	low_impact	-1,18	low_impact	-1,48	high_impact	2,56	0,68	0,9	12,48	34,19	N	0,38	N	0,88	polymorphism	0,97	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6367	6367	T	G	MI.2865	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	464	155	V	G	gTc/gGc	0,36	0,13	0	possibly_damaging	0,73	deleterious	0	neutral	2,43	deleterious	-5,39	deleterious	-4,06	high_impact	3,96	neutral	0,74	neutral	0,56	deleterious	3,46	23	0,21	0,55	disease	0,68	disease	0,77	disease	0,59	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	5	deleterious	0,69	low_impact	-1,16	low_impact	-1,48	high_impact	2,56	0,54	0,9	12,48	34,19	N	0,41	N	0,67	polymorphism	0,96	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6369	6369	T	A	MI.2866	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	466	156	S	T	Tcc/Acc	-12,13	0	0	probably_damaging	0,99	deleterious	0	neutral	2,56	neutral	-2,37	deleterious	-2,61	high_impact	5,24	damaging	0,51	damaging	0,15	deleterious	3,64	23,2	0,3	0,55	disease	0,56	disease	0,77	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	3,74	0,73	0,9	5,46	8,32	P	0,67	P	0,43	polymorphism	0,99	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6369	6369	T	C	MI.2867	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	466	156	S	P	Tcc/Ccc	-12,13	0	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-4,18	deleterious	-4,35	high_impact	5,24	damaging	0,4	damaging	0,2	deleterious	3,85	23,4	0,19	0,55	disease	0,76	disease	0,9	disease	0,81	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,59	0,9	5,46	8,32	P	0,67	P	0,91	polymorphism	0,97	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6369	6369	T	G	MI.2868	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	466	156	S	A	Tcc/Gcc	-12,13	0	0	probably_damaging	0,99	deleterious	0,02	neutral	2,72	neutral	-0,54	deleterious	-2,61	medium_impact	3,49	damaging	0,59	damaging	0,18	deleterious	3,54	23,1	0,33	0,55	neutral	0,37	disease	0,69	disease	0,64	disease	0,54	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,75	low_impact	-2,64	medium_impact	-0,75	high_impact	2,12	0,71	0,9	5,46	8,32	N	0,31	N	0,35	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6370	6370	C	T	MI.2869	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	467	156	S	F	tCc/tTc	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-4,16	deleterious	-5,21	high_impact	4,89	damaging	0,34	damaging	0,08	deleterious	4,18	23,8	0,14	0,55	disease	0,79	disease	0,94	disease	0,73	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,42	0,5	0,9	5,46	8,32	P	0,74	P	0,98	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8660	8660	C	A	MI.287	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	134	45	T	N	aCc/aAc	-2,65	0	0	possibly_damaging	0,48	deleterious	0	neutral	4,35	neutral	-1,61	neutral	-2,26	low_impact	0,92	neutral	0,83	neutral	0,63	deleterious	3,13	22,6	0,32	0,65	disease	0,74	disease	0,51	disease	0,56	disease	0,66	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,57	medium_impact	-0,72	low_impact	-1,4	medium_impact	-0,31	0,73	0,9	18,14	18,2	N	0,34	N	0,31	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6370	6370	C	G	MI.2870	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	467	156	S	C	tCc/tGc	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-5,13	deleterious	-4,35	high_impact	5,24	damaging	0,45	damaging	0,11	deleterious	3,49	23,1	0,21	0,55	disease	0,86	disease	0,87	disease	0,7	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,67	0,9	5,46	8,32	P	0,68	P	0,85	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6370	6370	C	A	MI.2871	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	467	156	S	Y	tCc/tAc	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-4,28	deleterious	-5,22	high_impact	5,24	damaging	0,47	damaging	0,12	deleterious	4,01	23,6	0,15	0,55	disease	0,79	disease	0,92	disease	0,73	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,63	0,9	5,46	8,32	P	0,69	P	0,92	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6372	6372	T	C	MI.2872	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	469	157	S	P	Tct/Cct	-14,45	0	0	probably_damaging	0,99	deleterious	0	neutral	2,66	deleterious	-4,01	deleterious	-4,35	high_impact	4,92	damaging	0,3	damaging	0,06	deleterious	3,87	23,5	0,2	0,55	disease	0,81	disease	0,88	disease	0,79	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,64	low_impact	-1,48	high_impact	3,44	0,54	0,9	2,73	6,64	P	0,62	P	0,91	polymorphism	0,92	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6372	6372	T	G	MI.2873	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	469	157	S	A	Tct/Gct	-14,45	0	0	probably_damaging	0,97	deleterious	0	neutral	2,74	neutral	-1,86	deleterious	-2,61	high_impact	4,12	damaging	0,54	damaging	0,11	deleterious	3,62	23,2	0,34	0,55	disease	0,54	disease	0,68	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-2,18	low_impact	-1,48	high_impact	2,71	0,7	0,9	2,73	6,64	N	0,29	N	0,35	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6372	6372	T	A	MI.2874	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	469	157	S	T	Tct/Act	-14,45	0	0	probably_damaging	0,95	deleterious	0	neutral	2,77	neutral	-1,49	deleterious	-2,6	medium_impact	3,27	damaging	0,45	damaging	0,07	deleterious	3,68	23,3	0,32	0,55	neutral	0,3	disease	0,75	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,73	low_impact	-1,96	low_impact	-1,48	medium_impact	1,92	0,72	0,9	2,73	6,64	N	0,32	N	0,43	polymorphism	0,99	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6373	6373	C	A	MI.2875	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	470	157	S	Y	tCt/tAt	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-3,41	deleterious	-5,22	high_impact	5,26	damaging	0,44	damaging	0,04	deleterious	3,9	23,5	0,18	0,55	disease	0,85	disease	0,92	disease	0,7	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,62	0,9	2,73	6,64	P	0,71	P	0,92	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6373	6373	C	T	MI.2876	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	470	157	S	F	tCt/tTt	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,73	neutral	-2,02	deleterious	-5,22	high_impact	4,71	damaging	0,41	damaging	0,02	deleterious	4,06	23,7	0,14	0,55	disease	0,84	disease	0,93	disease	0,7	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,25	0,31	0,9	2,73	6,64	P	0,73	P	0,98	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6373	6373	C	G	MI.2877	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	470	157	S	C	tCt/tGt	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,65	deleterious	-4,51	deleterious	-4,35	high_impact	5,26	damaging	0,44	damaging	0,02	deleterious	3,47	23	0,2	0,55	disease	0,87	disease	0,86	disease	0,67	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,62	0,9	2,73	6,64	P	0,69	P	0,85	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6375	6375	A	C	MI.2878	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	472	158	I	L	Atc/Ctc	-7,28	0	0	probably_damaging	0,94	neutral	0,05	neutral	2,86	neutral	-0,17	neutral	-1,72	medium_impact	2,5	neutral	0,67	damaging	0,06	deleterious	3,7	23,3	0,35	0,55	neutral	0,29	disease	0,66	neutral	0,36	neutral	0,18	6	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,59	low_impact	-1,88	medium_impact	-0,52	medium_impact	1,21	0,7	0,9	2,34	6,75	N	0,3	N	0,61	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6375	6375	A	G	MI.2879	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	472	158	I	V	Atc/Gtc	-7,28	0	0	possibly_damaging	0,85	deleterious	0	neutral	2,72	neutral	-1,18	neutral	-0,87	high_impact	3,78	neutral	0,65	damaging	0,08	deleterious	2,9	21,9	0,53	0,6	neutral	0,45	disease	0,54	disease	0,55	neutral	0,48	0	deleterious	1	neutral	0,08	deleterious	5	deleterious	0,58	low_impact	-1,47	low_impact	-1,48	high_impact	2,39	0,54	0,9	2,34	6,75	N	0,33	N	0,23	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8660	8660	C	G	MI.288	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	134	45	T	S	aCc/aGc	-2,65	0	0	benign	0,14	neutral	0,13	neutral	4,43	neutral	0,63	neutral	-1,29	neutral_impact	-0,21	neutral	0,9	neutral	0,74	neutral	1,59	13,79	0,47	0,65	neutral	0,41	neutral	0,26	disease	0,53	neutral	0,47	1	neutral	0,85	deleterious	0,5	neutral	-6	neutral	0,22	medium_impact	-0,01	medium_impact	-0,18	low_impact	-1,28	0,7	0,9	18,14	18,2	N	0,41	N	0,2	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6375	6375	A	T	MI.2880	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	472	158	I	F	Atc/Ttc	-7,28	0	0	probably_damaging	0,99	deleterious	0	neutral	2,59	neutral	-2,78	deleterious	-3,47	high_impact	4,64	neutral	0,61	damaging	0,05	deleterious	3,78	23,4	0,25	0,55	disease	0,8	disease	0,87	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,64	low_impact	-1,48	high_impact	3,19	0,74	0,9	2,34	6,75	N	0,45	N	0,85	disease_causing	0,68	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6376	6376	T	C	MI.2881	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	473	158	I	T	aTc/aCc	8,69	1	0	probably_damaging	1	deleterious	0,02	neutral	2,7	neutral	-0,94	deleterious	-4,33	high_impact	3,63	neutral	0,62	damaging	0,08	deleterious	3,29	22,8	0,37	0,55	disease	0,53	disease	0,77	disease	0,55	neutral	0,49	0	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,58	medium_impact	-0,75	high_impact	2,25	0,58	0,9	2,34	6,75	N	0,45	N	0,76	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6376	6376	T	A	MI.2882	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	473	158	I	N	aTc/aAc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-3,76	deleterious	-6,08	high_impact	5,2	neutral	0,61	damaging	0,07	deleterious	4,35	24,1	0,22	0,55	disease	0,93	disease	0,86	disease	0,63	disease	0,63	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,7	0,58	0,9	2,34	6,75	P	0,69	P	0,94	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6376	6376	T	G	MI.2883	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	473	158	I	S	aTc/aGc	8,69	1	0	probably_damaging	1	deleterious	0,03	neutral	2,58	neutral	-2,52	deleterious	-5,21	high_impact	4,64	neutral	0,64	damaging	0,09	deleterious	4,2	23,9	0,2	0,55	disease	0,87	disease	0,89	disease	0,6	disease	0,63	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,87	low_impact	-3,58	medium_impact	-0,65	high_impact	3,19	0,4	0,9	2,34	6,75	P	0,55	P	0,62	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6377	6377	C	A	MI.2884	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	474	158	I	M	atC/atA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,56	neutral	-2,29	deleterious	-2,59	high_impact	3,96	neutral	0,66	damaging	0,06	deleterious	3,7	23,3	0,35	0,55	disease	0,76	disease	0,71	disease	0,53	neutral	0,47	1	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,56	0,78	0,9	2,34	6,75	N	0,45	N	0,76	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6377	6377	C	G	MI.2885	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	474	158	I	M	atC/atG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,56	neutral	-2,29	deleterious	-2,59	high_impact	3,96	neutral	0,66	damaging	0,06	deleterious	3,29	22,8	0,35	0,55	disease	0,76	disease	0,71	disease	0,53	neutral	0,47	1	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,56	0,78	0,9	2,34	6,75	N	0,45	N	0,76	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6378	6378	T	A	MI.2886	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	475	159	L	M	Tta/Ata	-2,42	0	0	probably_damaging	1	neutral	0,05	neutral	2,46	neutral	-1,63	neutral	-1,13	low_impact	1,16	damaging	0,46	damaging	0,1	deleterious	2,41	18,87	0,39	0,55	neutral	0,46	neutral	0,38	neutral	0,29	neutral	0,42	2	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,72	low_impact	-3,58	medium_impact	-0,52	medium_impact	-0,03	0,78	0,9	1,17	6,77	N	0,4	N	0,59	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6378	6378	T	G	MI.2887	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	475	159	L	V	Tta/Gta	-2,42	0	0	probably_damaging	0,97	deleterious	0	neutral	2,51	neutral	-1,85	neutral	-2,35	medium_impact	3,49	damaging	0,53	damaging	0,08	deleterious	3,34	22,9	0,41	0,55	disease	0,51	disease	0,74	neutral	0,49	neutral	0,46	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,78	low_impact	-2,18	low_impact	-1,48	high_impact	2,12	0,66	0,9	1,17	6,77	N	0,27	N	0,66	polymorphism	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6379	6379	T	G	MI.2888	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	476	159	L	W	tTa/tGa	-3,11	0	0	probably_damaging	1	deleterious	0	neutral	2,37	deleterious	-5,74	deleterious	-4,85	high_impact	4,96	damaging	0,49	damaging	0,05	deleterious	3,67	23,2	0,15	0,55	disease	0,9	disease	0,85	disease	0,6	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,54	0,9	1,17	6,77	P	0,54	P	0,92	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6379	6379	T	C	MI.2889	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	476	159	L	S	tTa/tCa	-3,11	0	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-3,24	deleterious	-4,84	high_impact	3,76	damaging	0,54	damaging	0,07	deleterious	3,67	23,3	0,26	0,55	disease	0,72	disease	0,85	disease	0,58	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,37	0,64	0,9	1,17	6,77	N	0,29	N	0,73	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8660	8660	C	T	MI.289	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	134	45	T	I	aCc/aTc	-2,65	0	0	benign	0,01	neutral	0,49	neutral	4,53	neutral	1,7	neutral	2,06	neutral_impact	-1,42	neutral	0,87	neutral	0,96	deleterious	0,5	7,4	0,33	0,65	neutral	0,27	neutral	0,2	neutral	0,29	neutral	0,36	3	neutral	0,5	deleterious	0,74	neutral	-6	neutral	0,13	medium_impact	1,14	medium_impact	0,28	low_impact	-2,31	0,63	0,9	18,14	18,2	N	0,31	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6380	6380	A	C	MI.2890	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	477	159	L	F	ttA/ttC	7,53	0,97	0	probably_damaging	1	deleterious	0,02	neutral	2,42	deleterious	-3,19	deleterious	-3,22	medium_impact	3,37	damaging	0,51	damaging	0,05	deleterious	3,4	23	0,4	0,55	disease	0,59	disease	0,83	neutral	0,5	disease	0,59	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-3,58	medium_impact	-0,75	high_impact	2,01	0,68	0,9	1,17	6,77	N	0,45	N	0,87	polymorphism	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6380	6380	A	T	MI.2891	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	477	159	L	F	ttA/ttT	7,53	0,97	0	probably_damaging	1	deleterious	0,02	neutral	2,42	deleterious	-3,19	deleterious	-3,22	medium_impact	3,37	damaging	0,51	damaging	0,05	deleterious	3,51	23,1	0,4	0,55	disease	0,59	disease	0,83	neutral	0,5	disease	0,59	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-3,58	medium_impact	-0,75	high_impact	2,01	0,68	0,9	1,17	6,77	N	0,45	N	0,87	polymorphism	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6381	6381	G	C	MI.2892	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	478	160	G	R	Ggg/Cgg	-3,57	0	0	probably_damaging	0,97	deleterious	0,02	neutral	2,78	neutral	-2,88	deleterious	-6,25	high_impact	4,83	neutral	0,65	damaging	0,07	deleterious	3,89	23,5	0,14	0,55	disease	0,67	disease	0,92	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,9	low_impact	-2,18	medium_impact	-0,75	high_impact	3,36	0,83	0,9	4,48	16,12	P	0,59	P	0,95	disease_causing	0,59	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6381	6381	G	T	MI.2893	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	478	160	G	W	Ggg/Tgg	-3,57	0	0	probably_damaging	0,99	deleterious	0	neutral	2,82	neutral	-1,91	deleterious	-6,45	high_impact	5,17	neutral	0,66	damaging	0,08	deleterious	4,38	24,1	0,14	0,55	disease	0,92	disease	0,92	disease	0,67	disease	0,62	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,91	low_impact	-2,64	low_impact	-1,48	high_impact	3,68	0,41	0,9	4,48	16,12	P	0,58	P	0,83	disease_causing	0,71	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6382	6382	G	A	MI.2894	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	479	160	G	E	gGg/gAg	5,22	1	0	probably_damaging	0,92	deleterious	0	neutral	2,78	neutral	-2,93	deleterious	-6,24	high_impact	4,83	neutral	0,64	damaging	0,09	deleterious	3,86	23,5	0,22	0,55	disease	0,61	disease	0,92	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,87	low_impact	-1,76	low_impact	-1,48	high_impact	3,36	0,73	0,9	4,48	16,12	P	0,67	P	0,93	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6382	6382	G	C	MI.2895	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	479	160	G	A	gGg/gCg	5,22	1	0	benign	0,42	neutral	0,1	neutral	2,88	neutral	-0,93	deleterious	-4,21	medium_impact	2,5	neutral	0,64	damaging	0,2	deleterious	1,94	15,81	0,3	0,55	neutral	0,28	disease	0,68	neutral	0,41	neutral	0,17	7	neutral	0,89	neutral	0,34	neutral	-3	deleterious	0,55	medium_impact	-0,62	medium_impact	-0,34	medium_impact	1,21	0,76	0,9	4,48	16,12	P	0,51	P	0,64	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6382	6382	G	T	MI.2896	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	479	160	G	V	gGg/gTg	5,22	1	0	probably_damaging	0,97	deleterious	0	neutral	2,85	neutral	-1,33	deleterious	-6,92	high_impact	5,17	neutral	0,65	damaging	0,08	deleterious	3,7	23,3	0,14	0,55	disease	0,57	disease	0,91	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-2,18	low_impact	-1,48	high_impact	3,68	0,68	0,9	4,48	16,12	P	0,64	P	0,93	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6384	6384	G	C	MI.2897	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	481	161	A	P	Gcc/Ccc	-12,37	0	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-4,47	deleterious	-3,89	high_impact	4,99	neutral	0,61	damaging	0,15	deleterious	3,78	23,4	0,13	0,55	disease	0,75	disease	0,94	disease	0,72	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,51	0,73	0,9	5,65	17,91	P	0,65	P	0,85	polymorphism	0,8	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6384	6384	G	T	MI.2898	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	481	161	A	S	Gcc/Tcc	-12,37	0	0	probably_damaging	1	neutral	0,4	neutral	2,7	neutral	-0,67	neutral	-1,69	low_impact	1,04	neutral	0,63	neutral	0,51	deleterious	2,37	18,62	0,32	0,55	neutral	0,3	disease	0,7	neutral	0,33	neutral	0,23	6	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,78	low_impact	-3,58	medium_impact	0,1	medium_impact	-0,14	0,8	0,9	5,65	17,91	N	0,36	N	0,64	polymorphism	0,97	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6384	6384	G	A	MI.2899	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	481	161	A	T	Gcc/Acc	-12,37	0	0	probably_damaging	1	deleterious	0	neutral	2,58	neutral	-2,06	deleterious	-2,86	high_impact	4,29	damaging	0,56	damaging	0,19	deleterious	4,14	23,8	0,4	0,55	disease	0,52	disease	0,89	disease	0,52	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,86	0,74	0,9	5,65	17,91	N	0,38	N	0,2	polymorphism	0,93	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8538	8538	T	G	MI.29	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	12	4	N	K	aaT/aaG	1,75	0,93	0	benign	0,07	deleterious	0	neutral	4,49	neutral	-0,72	deleterious	-3,89	medium_impact	2,85	neutral	0,87	neutral	0,35	deleterious	4,26	23,9	0,63	0,7	disease	0,6	disease	0,52	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,47	deleterious	1	neutral	0,33	medium_impact	0,31	low_impact	-1,4	medium_impact	1,35	0,28	0,9	41,59	7,51	N	0,48	N	0,94	disease_causing	0,69	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8662	8662	C	G	MI.290	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	136	46	Q	E	Caa/Gaa	-9,82	0	0	probably_damaging	0,94	neutral	0,27	neutral	4,33	neutral	-1,83	deleterious	-2,81	high_impact	3,62	neutral	0,85	damaging	0,16	deleterious	2,94	22	0,46	0,65	disease	0,77	disease	0,76	disease	0,59	disease	0,66	3	neutral	0,95	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-1,89	medium_impact	0,05	high_impact	2,01	0,84	0,9	49,56	8,75	N	0,28	N	0,94	polymorphism	0,99	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6385	6385	C	A	MI.2900	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	482	161	A	D	gCc/gAc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-4,65	deleterious	-4,45	high_impact	4,99	neutral	0,64	damaging	0,13	deleterious	4,38	24,1	0,11	0,55	disease	0,68	disease	0,95	disease	0,7	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,51	0,7	0,9	5,65	17,91	P	0,68	P	0,89	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6385	6385	C	G	MI.2901	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	482	161	A	G	gCc/gGc	9,15	1	0	probably_damaging	1	neutral	0,06	neutral	2,63	neutral	-1,35	deleterious	-3,02	medium_impact	3,42	neutral	0,63	damaging	0,17	deleterious	3,86	23,5	0,23	0,55	neutral	0,3	disease	0,86	neutral	0,5	disease	0,51	0	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,75	low_impact	-3,58	medium_impact	-0,47	high_impact	2,06	0,77	0,9	5,65	17,91	P	0,52	P	0,56	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6385	6385	C	T	MI.2902	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	482	161	A	V	gCc/gTc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,62	neutral	-1,43	deleterious	-3,32	high_impact	4,99	neutral	0,61	damaging	0,14	deleterious	4,41	24,1	0,39	0,55	neutral	0,49	disease	0,91	disease	0,6	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,51	0,75	0,9	5,65	17,91	P	0,71	P	0,75	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6387	6387	A	C	MI.2903	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	484	162	I	L	Atc/Ctc	-11,44	0	0	probably_damaging	0,98	neutral	0,06	neutral	2,72	neutral	-0,48	neutral	-1,66	medium_impact	2,12	damaging	0,51	damaging	0,1	deleterious	2,64	20,5	0,34	0,55	neutral	0,39	disease	0,72	neutral	0,32	neutral	0,36	3	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,68	low_impact	-2,35	medium_impact	-0,47	medium_impact	0,86	0,77	0,9	0,97	6,72	N	0,33	N	0,61	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6387	6387	A	T	MI.2904	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	484	162	I	F	Atc/Ttc	-11,44	0	0	probably_damaging	1	deleterious	0	neutral	2,64	neutral	-1,2	deleterious	-3,42	high_impact	4,81	damaging	0,52	damaging	0,05	deleterious	3,81	23,4	0,26	0,55	disease	0,81	disease	0,89	disease	0,59	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,34	0,78	0,9	0,97	6,72	P	0,62	P	0,85	polymorphism	0,72	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6387	6387	A	G	MI.2905	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	484	162	I	V	Atc/Gtc	-11,44	0	0	probably_damaging	0,95	neutral	0,17	neutral	2,75	neutral	-0,34	neutral	-0,37	low_impact	0,8	damaging	0,57	damaging	0,22	neutral	1,1	11,24	0,51	0,6	neutral	0,26	neutral	0,23	neutral	0,33	neutral	0,4	2	neutral	0,97	neutral	0,11	neutral	-2	deleterious	0,59	low_impact	-1,96	medium_impact	-0,19	medium_impact	-0,36	0,7	0,9	0,97	6,72	N	0,4	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6388	6388	T	G	MI.2906	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	485	162	I	S	aTc/aGc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-3,03	deleterious	-4,9	high_impact	4,46	damaging	0,49	damaging	0,1	deleterious	4,22	23,9	0,24	0,55	disease	0,85	disease	0,9	disease	0,59	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,02	0,62	0,9	0,97	6,72	N	0,48	N	0,62	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6388	6388	T	A	MI.2907	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	485	162	I	N	aTc/aAc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-4,28	deleterious	-5,77	high_impact	4,81	damaging	0,5	damaging	0,05	deleterious	4,35	24,1	0,2	0,55	disease	0,92	disease	0,88	disease	0,58	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,34	0,69	0,9	0,97	6,72	P	0,65	P	0,94	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6388	6388	T	C	MI.2908	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	485	162	I	T	aTc/aCc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,57	neutral	-2,18	deleterious	-3,79	medium_impact	3,46	damaging	0,49	damaging	0,06	deleterious	3,35	22,9	0,39	0,55	disease	0,6	disease	0,81	disease	0,57	disease	0,67	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,1	0,71	0,9	0,97	6,72	N	0,43	N	0,76	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6389	6389	C	G	MI.2909	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	486	162	I	M	atC/atG	7,53	1	0	probably_damaging	1	neutral	0,05	neutral	2,54	neutral	-2,88	neutral	-2,27	medium_impact	3,06	damaging	0,54	damaging	0,07	deleterious	3,24	22,8	0,33	0,55	disease	0,79	disease	0,64	neutral	0,35	neutral	0,47	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,77	low_impact	-3,58	medium_impact	-0,52	medium_impact	1,73	0,8	0,9	0,97	6,72	P	0,49	N	0,76	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8662	8662	C	A	MI.291	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	136	46	Q	K	Caa/Aaa	-9,82	0	0	probably_damaging	0,97	neutral	0,29	neutral	4,34	neutral	-1,56	deleterious	-3,74	low_impact	1,91	neutral	0,8	damaging	0,14	deleterious	3,86	23,5	0,38	0,65	disease	0,75	disease	0,8	neutral	0,48	disease	0,59	2	neutral	0,98	neutral	0,16	neutral	-2	deleterious	0,82	low_impact	-2,19	medium_impact	0,07	medium_impact	0,54	0,72	0,9	49,56	8,75	N	0,24	N	0,98	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6389	6389	C	A	MI.2910	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	486	162	I	M	atC/atA	7,53	1	0	probably_damaging	1	neutral	0,05	neutral	2,54	neutral	-2,88	neutral	-2,27	medium_impact	3,06	damaging	0,54	damaging	0,07	deleterious	3,72	23,3	0,33	0,55	disease	0,79	disease	0,64	neutral	0,35	neutral	0,47	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,77	low_impact	-3,58	medium_impact	-0,52	medium_impact	1,73	0,8	0,9	0,97	6,72	P	0,49	N	0,76	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6390	6390	A	C	MI.2911	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	487	163	N	H	Aat/Cat	-2,65	0	0	possibly_damaging	0,87	deleterious	0	neutral	2,5	deleterious	-4,78	deleterious	-4,35	high_impact	5,32	neutral	0,61	damaging	0,1	deleterious	3	22,2	0,29	0,55	disease	0,79	disease	0,91	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,83	low_impact	-1,53	low_impact	-1,48	high_impact	3,81	0,62	0,9	1,56	7,11	P	0,69	P	0,83	polymorphism	0,97	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6390	6390	A	T	MI.2912	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	487	163	N	Y	Aat/Tat	-2,65	0	0	probably_damaging	0,94	deleterious	0	neutral	2,51	deleterious	-4,03	deleterious	-6,96	high_impact	5,32	damaging	0,59	damaging	0,11	deleterious	3,62	23,2	0,2	0,55	disease	0,85	disease	0,95	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,88	low_impact	-1,88	low_impact	-1,48	high_impact	3,81	0,48	0,9	1,56	7,11	P	0,58	P	0,93	polymorphism	0,9	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6390	6390	A	G	MI.2913	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	487	163	N	D	Aat/Gat	-2,65	0	0	benign	0,21	deleterious	0	neutral	2,53	deleterious	-3,43	deleterious	-4,35	high_impact	5,32	damaging	0,47	damaging	0,16	deleterious	3,77	23,4	0,36	0,55	disease	0,59	disease	0,89	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,4	deleterious	2	neutral	0,42	medium_impact	-0,22	low_impact	-1,48	high_impact	3,81	0,66	0,9	1,56	7,11	P	0,63	P	0,92	polymorphism	0,99	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6391	6391	A	C	MI.2914	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	488	163	N	T	aAt/aCt	8,69	1	0	benign	0,38	deleterious	0	neutral	2,53	deleterious	-3,6	deleterious	-5,22	high_impact	5,32	neutral	0,61	damaging	0,14	deleterious	3,36	22,9	0,29	0,55	disease	0,67	disease	0,92	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,58	medium_impact	-0,56	low_impact	-1,48	high_impact	3,81	0,62	0,9	1,56	7,11	P	0,65	P	0,59	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6391	6391	A	G	MI.2915	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	488	163	N	S	aAt/aGt	8,69	1	0	benign	0,09	deleterious	0	neutral	2,54	deleterious	-3,22	deleterious	-4,35	high_impact	5,32	neutral	0,63	damaging	0,12	deleterious	3,05	22,4	0,41	0,55	disease	0,61	disease	0,91	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,46	deleterious	2	neutral	0,39	medium_impact	0,19	low_impact	-1,48	high_impact	3,81	0,62	0,9	1,56	7,11	P	0,67	P	0,79	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6391	6391	A	T	MI.2916	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	488	163	N	I	aAt/aTt	8,69	1	0	possibly_damaging	0,89	deleterious	0	neutral	2,56	neutral	-2,76	deleterious	-7,83	high_impact	5,32	damaging	0,52	damaging	0,13	deleterious	4,08	23,7	0,21	0,55	neutral	0,39	disease	0,96	disease	0,69	disease	0,78	6	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,8	low_impact	-1,61	low_impact	-1,48	high_impact	3,81	0,44	0,9	1,56	7,11	P	0,61	P	0,98	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6392	6392	T	G	MI.2917	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	489	163	N	K	aaT/aaG	8,69	1	0,16	benign	0,03	deleterious	0	neutral	2,51	deleterious	-4,07	deleterious	-5,22	high_impact	4,97	damaging	0,54	damaging	0,1	deleterious	3,96	23,6	0,32	0,55	disease	0,56	disease	0,94	disease	0,77	disease	0,83	7	deleterious	1	deleterious	0,49	deleterious	2	neutral	0,36	medium_impact	0,66	low_impact	-1,48	high_impact	3,49	0,66	0,9	1,56	7,11	P	0,66	P	0,92	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6392	6392	T	A	MI.2918	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	489	163	N	K	aaT/aaA	8,69	1	0,16	benign	0,03	deleterious	0	neutral	2,51	deleterious	-4,07	deleterious	-5,22	high_impact	4,97	damaging	0,54	damaging	0,1	deleterious	4,3	24	0,32	0,55	disease	0,56	disease	0,94	disease	0,77	disease	0,83	7	deleterious	1	deleterious	0,49	deleterious	2	neutral	0,36	medium_impact	0,66	low_impact	-1,48	high_impact	3,49	0,66	0,9	1,56	7,11	P	0,66	P	0,92	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6393	6393	T	C	MI.2919	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	490	164	F	L	Ttc/Ctc	-3,57	0	0	probably_damaging	1	deleterious	0,01	neutral	2,74	neutral	-0,35	deleterious	-5,2	high_impact	3,72	neutral	0,8	damaging	0,03	deleterious	4,12	23,8	0,4	0,55	neutral	0,34	disease	0,75	neutral	0,49	neutral	0,35	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,75	low_impact	-3,58	medium_impact	-0,92	high_impact	2,34	0,71	0,9	2,92	8,17	N	0,28	N	0,83	polymorphism	0,95	0,23	rs879212050	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8663	8663	A	C	MI.292	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	137	46	Q	P	cAa/cCa	4,52	1	0	probably_damaging	0,98	neutral	0,2	neutral	4,33	neutral	-2,27	deleterious	-5,62	medium_impact	3,06	neutral	0,76	damaging	0,15	deleterious	3,15	22,6	0,19	0,65	disease	0,85	disease	0,9	disease	0,64	disease	0,78	6	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,89	low_impact	-2,36	medium_impact	-0,05	medium_impact	1,53	0,7	0,9	49,56	8,75	N	0,4	N	0,97	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6393	6393	T	A	MI.2920	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	490	164	F	I	Ttc/Atc	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-0,68	deleterious	-5,2	high_impact	3,88	neutral	0,7	damaging	0,05	deleterious	4,57	24,4	0,23	0,55	disease	0,58	disease	0,84	disease	0,6	disease	0,6	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,48	0,64	0,9	2,92	8,17	N	0,28	N	0,88	polymorphism	0,96	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6393	6393	T	G	MI.2921	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	490	164	F	V	Ttc/Gtc	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,66	neutral	-0,94	deleterious	-6,07	high_impact	4,46	neutral	0,67	damaging	0,04	deleterious	4,13	23,8	0,24	0,55	disease	0,56	disease	0,88	disease	0,66	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,02	0,63	0,9	2,92	8,17	N	0,39	N	0,84	polymorphism	0,91	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6394	6394	T	A	MI.2922	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	491	164	F	Y	tTc/tAc	5,91	1	0	probably_damaging	1	deleterious	0,04	neutral	2,51	deleterious	-3,1	deleterious	-2,6	high_impact	4,17	neutral	0,66	damaging	0,04	deleterious	4,11	23,8	0,28	0,55	disease	0,63	disease	0,79	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,81	low_impact	-3,58	medium_impact	-0,58	high_impact	2,75	0,73	0,9	2,92	8,17	P	0,57	P	0,59	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6394	6394	T	G	MI.2923	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	491	164	F	C	tTc/tGc	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-4,47	deleterious	-6,95	high_impact	5,26	neutral	0,66	damaging	0,03	deleterious	4,03	23,6	0,2	0,55	disease	0,86	disease	0,86	disease	0,68	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,49	0,9	2,92	8,17	P	0,66	P	0,91	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6394	6394	T	C	MI.2924	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	491	164	F	S	tTc/tCc	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,54	neutral	-2,46	deleterious	-6,94	high_impact	4,57	neutral	0,7	damaging	0,05	deleterious	4,19	23,8	0,22	0,55	disease	0,73	disease	0,87	disease	0,65	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,12	0,58	0,9	2,92	8,17	P	0,56	P	0,84	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6395	6395	C	A	MI.2925	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	492	164	F	L	ttC/ttA	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	2,74	neutral	-0,35	deleterious	-5,2	high_impact	3,72	neutral	0,8	damaging	0,03	deleterious	4,63	24,5	0,4	0,55	neutral	0,34	disease	0,75	neutral	0,49	neutral	0,35	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,75	low_impact	-3,58	medium_impact	-0,92	high_impact	2,34	0,71	0,9	2,92	8,17	N	0,47	N	0,83	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6395	6395	C	G	MI.2926	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	492	164	F	L	ttC/ttG	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	2,74	neutral	-0,35	deleterious	-5,2	high_impact	3,72	neutral	0,8	damaging	0,03	deleterious	4,29	24	0,4	0,55	neutral	0,34	disease	0,75	neutral	0,49	neutral	0,35	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,75	low_impact	-3,58	medium_impact	-0,92	high_impact	2,34	0,71	0,9	2,92	8,17	N	0,47	N	0,83	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6396	6396	A	T	MI.2927	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	493	165	I	F	Atc/Ttc	-3,11	0	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-2	deleterious	-3,33	high_impact	4,42	damaging	0,56	damaging	0,04	deleterious	3,68	23,3	0,32	0,55	disease	0,75	disease	0,83	disease	0,61	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,98	0,81	0,9	2,73	6,7	N	0,36	N	0,85	disease_causing	0,97	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6396	6396	A	G	MI.2928	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	493	165	I	V	Atc/Gtc	-3,11	0	0	probably_damaging	0,95	deleterious	0,04	neutral	2,77	neutral	-0,74	neutral	-0,83	medium_impact	3,1	damaging	0,58	damaging	0,07	deleterious	2,97	22,1	0,59	0,65	neutral	0,39	disease	0,5	disease	0,52	neutral	0,46	1	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,66	low_impact	-1,96	medium_impact	-0,58	medium_impact	1,76	0,68	0,9	2,73	6,7	N	0,35	N	0,23	polymorphism	0,85	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6396	6396	A	C	MI.2929	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	493	165	I	L	Atc/Ctc	-3,11	0	0	probably_damaging	0,98	neutral	0,09	neutral	2,81	neutral	-0,75	neutral	-1,56	medium_impact	2,34	neutral	0,63	damaging	0,05	deleterious	3,73	23,3	0,35	0,55	neutral	0,27	disease	0,63	neutral	0,37	neutral	0,2	6	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,65	low_impact	-2,35	medium_impact	-0,37	medium_impact	1,06	0,77	0,9	2,73	6,7	N	0,3	N	0,61	polymorphism	0,71	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8663	8663	A	G	MI.293	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	137	46	Q	R	cAa/cGa	4,52	1	0	probably_damaging	0,97	neutral	0,35	neutral	4,36	neutral	-0,65	deleterious	-3,74	medium_impact	2,71	neutral	0,89	damaging	0,15	deleterious	3,35	22,9	0,49	0,65	disease	0,78	disease	0,79	disease	0,63	disease	0,66	3	neutral	0,97	neutral	0,19	deleterious	1	deleterious	0,83	low_impact	-2,19	medium_impact	0,14	medium_impact	1,23	0,66	0,9	49,56	8,75	N	0,47	N	0,87	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6397	6397	T	A	MI.2930	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	494	165	I	N	aTc/aAc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-4,39	deleterious	-5,91	high_impact	5,11	damaging	0,53	damaging	0,05	deleterious	4,38	24,1	0,3	0,55	disease	0,92	disease	0,83	disease	0,61	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,71	0,9	2,73	6,7	P	0,63	P	0,94	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6397	6397	T	G	MI.2931	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	494	165	I	S	aTc/aGc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-3,16	deleterious	-5,03	high_impact	4,76	damaging	0,59	damaging	0,07	deleterious	4,23	23,9	0,27	0,55	disease	0,84	disease	0,86	disease	0,59	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,63	0,9	2,73	6,7	P	0,67	P	0,62	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6397	6397	T	C	MI.2932	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	494	165	I	T	aTc/aCc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,65	neutral	-2,68	deleterious	-4,2	high_impact	4,21	damaging	0,57	damaging	0,05	deleterious	3,37	22,9	0,46	0,55	disease	0,77	disease	0,79	disease	0,58	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,79	0,74	0,9	2,73	6,7	N	0,45	N	0,76	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6398	6398	C	G	MI.2933	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	495	165	I	M	atC/atG	7,53	1	0	probably_damaging	1	neutral	0,23	neutral	2,62	neutral	-2,69	neutral	-2,29	medium_impact	2,3	damaging	0,51	damaging	0,1	deleterious	3,17	22,7	0,47	0,55	disease	0,54	disease	0,6	neutral	0,38	neutral	0,22	6	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,74	low_impact	-3,58	medium_impact	-0,1	medium_impact	1,03	0,9	0,95	2,73	6,7	P	0,5	N	0,76	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6398	6398	C	A	MI.2934	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	495	165	I	M	atC/atA	7,53	1	0	probably_damaging	1	neutral	0,23	neutral	2,62	neutral	-2,69	neutral	-2,29	medium_impact	2,3	damaging	0,51	damaging	0,1	deleterious	3,61	23,2	0,47	0,55	disease	0,54	disease	0,6	neutral	0,38	neutral	0,22	6	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,74	low_impact	-3,58	medium_impact	-0,1	medium_impact	1,03	0,9	0,95	2,73	6,7	P	0,51	P	0,76	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6399	6399	A	C	MI.2935	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	496	166	T	P	Aca/Cca	-1,26	0,01	0	probably_damaging	1	deleterious	0	neutral	2,73	deleterious	-3,41	deleterious	-4	high_impact	4,65	neutral	0,62	damaging	0,13	deleterious	3,41	23	0,12	0,55	disease	0,67	disease	0,88	disease	0,68	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,2	0,67	0,9	2,53	7,17	N	0,5	N	0,92	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6399	6399	A	G	MI.2936	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	496	166	T	A	Aca/Gca	-1,26	0,01	0	probably_damaging	0,98	deleterious	0,01	neutral	2,85	neutral	-0,65	deleterious	-2,74	medium_impact	2,44	neutral	0,62	damaging	0,17	deleterious	3,35	22,9	0,53	0,6	neutral	0,23	disease	0,55	neutral	0,39	neutral	0,21	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,68	low_impact	-2,35	medium_impact	-0,92	medium_impact	1,15	0,69	0,9	2,53	7,17	N	0,33	N	0,69	disease_causing	0,98	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6399	6399	A	T	MI.2937	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	496	166	T	S	Aca/Tca	-1,26	0,01	0	probably_damaging	0,98	neutral	0,09	neutral	2,79	neutral	-1,72	neutral	-1,57	neutral_impact	0,61	damaging	0,52	damaging	0,27	deleterious	1,81	15,03	0,42	0,55	neutral	0,35	neutral	0,29	neutral	0,31	neutral	0,44	1	deleterious	0,99	neutral	0,06	neutral	-2	deleterious	0,69	low_impact	-2,35	medium_impact	-0,37	medium_impact	-0,54	0,77	0,9	2,53	7,17	N	0,42	N	0,79	disease_causing	0,93	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6400	6400	C	T	MI.2938	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	497	166	T	M	aCa/aTa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,82	neutral	-2,77	deleterious	-3,9	high_impact	4,65	neutral	0,74	damaging	0,12	deleterious	3,96	23,6	0,27	0,55	neutral	0,45	disease	0,77	disease	0,58	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	high_impact	3,2	0,87	0,9	2,53	7,17	P	0,51	P	0,96	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6400	6400	C	A	MI.2939	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	497	166	T	K	aCa/aAa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,77	neutral	-2,25	deleterious	-3,75	high_impact	4,65	neutral	0,65	damaging	0,11	deleterious	4,4	24,1	0,13	0,55	disease	0,56	disease	0,9	disease	0,67	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,2	0,76	0,9	2,53	7,17	P	0,56	P	0,88	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8663	8663	A	T	MI.294	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	137	46	Q	L	cAa/cTa	4,52	1	0	probably_damaging	0,97	neutral	0,65	neutral	4,58	neutral	1,81	deleterious	-6,54	low_impact	0,84	neutral	0,9	damaging	0,15	deleterious	3,67	23,2	0,21	0,65	neutral	0,34	disease	0,78	neutral	0,35	disease	0,53	1	neutral	0,97	neutral	0,34	neutral	-2	deleterious	0,75	low_impact	-2,19	medium_impact	0,44	medium_impact	-0,38	0,33	0,9	49,56	8,75	N	0,35	N	0,99	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6402	6402	A	G	MI.2940	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	499	167	T	A	Aca/Gca	-11,44	0	0	probably_damaging	0,98	deleterious	0	neutral	1,92	deleterious	-3,7	deleterious	-4,33	high_impact	4,94	neutral	0,73	damaging	0,08	deleterious	3,41	23	0,39	0,55	disease	0,59	disease	0,61	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,35	low_impact	-1,48	high_impact	3,46	0,62	0,9	2,34	6,67	P	0,6	P	0,69	polymorphism	0,97	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6402	6402	A	C	MI.2941	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	499	167	T	P	Aca/Cca	-11,44	0	0	probably_damaging	1	deleterious	0	neutral	1,83	deleterious	-6,38	deleterious	-5,21	high_impact	5,29	damaging	0,57	damaging	0,08	deleterious	3,4	23	0,16	0,55	disease	0,85	disease	0,82	disease	0,79	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,67	0,9	2,34	6,67	P	0,59	P	0,92	polymorphism	0,87	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6402	6402	A	T	MI.2942	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	499	167	T	S	Aca/Tca	-11,44	0	0	probably_damaging	0,98	deleterious	0	neutral	1,89	deleterious	-4,17	deleterious	-3,46	medium_impact	3,17	neutral	0,68	damaging	0,09	deleterious	3,28	22,8	0,34	0,55	disease	0,64	disease	0,7	disease	0,61	disease	0,56	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,77	low_impact	-2,35	low_impact	-1,48	medium_impact	1,83	0,73	0,9	2,34	6,67	N	0,24	N	0,79	polymorphism	0,99	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6403	6403	C	A	MI.2943	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	500	167	T	K	aCa/aAa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	1,86	deleterious	-4,96	deleterious	-5,21	high_impact	5,29	neutral	0,64	damaging	0,06	deleterious	4,43	24,2	0,19	0,55	disease	0,78	disease	0,9	disease	0,77	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,77	0,9	2,34	6,67	P	0,73	P	0,88	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6403	6403	C	T	MI.2944	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	500	167	T	M	aCa/aTa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	1,83	deleterious	-6,31	deleterious	-5,21	high_impact	5,29	neutral	0,7	damaging	0,07	deleterious	3,89	23,5	0,35	0,55	neutral	0,38	disease	0,82	disease	0,69	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,78	0,9	2,34	6,67	P	0,62	P	0,96	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6405	6405	A	T	MI.2945	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	502	168	I	F	Att/Ttt	-5,19	0	0	possibly_damaging	0,68	neutral	0,08	neutral	2,44	deleterious	-3,14	deleterious	-2,99	medium_impact	3,34	neutral	0,66	damaging	0,1	deleterious	3,98	23,6	0,34	0,55	disease	0,54	disease	0,81	neutral	0,48	disease	0,6	2	neutral	0,93	neutral	0,2	NA	0	deleterious	0,67	low_impact	-1,06	medium_impact	-0,4	medium_impact	1,99	0,8	0,9	5,85	15,28	N	0,28	N	0,85	polymorphism	0,98	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6405	6405	A	C	MI.2946	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	502	168	I	L	Att/Ctt	-5,19	0	0	benign	0,12	deleterious	0,03	neutral	2,64	neutral	-0,83	neutral	-1,32	medium_impact	2,99	neutral	0,66	damaging	0,12	deleterious	3,65	23,2	0,38	0,55	neutral	0,35	disease	0,69	neutral	0,5	neutral	0,47	1	neutral	0,97	neutral	0,46	deleterious	1	neutral	0,19	medium_impact	0,06	medium_impact	-0,65	medium_impact	1,66	0,79	0,9	5,85	15,28	N	0,31	N	0,61	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6405	6405	A	G	MI.2947	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	502	168	I	V	Att/Gtt	-5,19	0	0	benign	0	neutral	0,19	neutral	2,63	neutral	-0,85	neutral	-0,26	low_impact	1,21	neutral	0,66	damaging	0,27	neutral	1,04	10,91	0,61	0,65	neutral	0,25	neutral	0,21	neutral	0,32	neutral	0,36	3	neutral	0,81	deleterious	0,6	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	-0,16	medium_impact	0,02	0,71	0,9	5,85	15,28	N	0,48	N	0,23	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6406	6406	T	G	MI.2948	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	503	168	I	S	aTt/aGt	3,14	0,75	0	possibly_damaging	0,87	neutral	0,11	neutral	2,42	deleterious	-3,52	deleterious	-4,09	medium_impact	3,15	neutral	0,68	damaging	0,24	deleterious	4,12	23,8	0,28	0,55	disease	0,54	disease	0,85	disease	0,53	disease	0,63	3	neutral	0,95	neutral	0,12	NA	0	deleterious	0,69	low_impact	-1,53	medium_impact	-0,31	medium_impact	1,81	0,71	0,9	5,85	15,28	N	0,35	N	0,62	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6406	6406	T	C	MI.2949	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	503	168	I	T	aTt/aCt	3,14	0,75	0	possibly_damaging	0,66	neutral	0,29	neutral	2,44	neutral	-2,91	deleterious	-3,15	medium_impact	2,56	neutral	0,66	damaging	0,27	deleterious	2,23	17,73	0,39	0,55	neutral	0,33	disease	0,71	neutral	0,35	neutral	0,49	0	neutral	0,76	neutral	0,32	NA	0	deleterious	0,45	low_impact	-1,03	medium_impact	-0,02	medium_impact	1,27	0,75	0,9	5,85	15,28	N	0,35	N	0,76	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8664	8664	A	C	MI.295	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	138	46	Q	H	caA/caC	6,84	1	0	probably_damaging	1	neutral	0,54	neutral	4,33	neutral	-2,21	deleterious	-4,67	medium_impact	3,27	neutral	0,82	damaging	0,13	deleterious	3,32	22,9	0,54	0,65	disease	0,84	disease	0,74	neutral	0,47	disease	0,61	2	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,33	medium_impact	1,71	0,78	0,9	49,56	8,75	N	0,46	N	0,95	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6406	6406	T	A	MI.2950	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	503	168	I	N	aTt/aAt	3,14	0,75	0	probably_damaging	0,97	deleterious	0	neutral	2,41	deleterious	-4,25	deleterious	-5,05	high_impact	3,75	neutral	0,65	damaging	0,12	deleterious	4,44	24,2	0,3	0,55	disease	0,71	disease	0,85	disease	0,55	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-2,18	low_impact	-1,48	high_impact	2,36	0,77	0,9	5,85	15,28	N	0,37	N	0,94	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6407	6407	T	A	MI.2951	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	504	168	I	M	atT/atA	1,98	0,74	0	possibly_damaging	0,87	deleterious	0,02	neutral	2,46	neutral	-2,52	neutral	-1,6	medium_impact	2,48	neutral	0,69	damaging	0,2	deleterious	2,61	20,3	0,51	0,6	neutral	0,5	disease	0,58	neutral	0,33	neutral	0,46	1	deleterious	0,99	neutral	0,08	deleterious	4	deleterious	0,56	low_impact	-1,53	medium_impact	-0,75	medium_impact	1,19	0,86	0,9	5,85	15,28	N	0,33	N	0,76	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6407	6407	T	G	MI.2952	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	504	168	I	M	atT/atG	1,98	0,74	0	possibly_damaging	0,87	deleterious	0,02	neutral	2,46	neutral	-2,52	neutral	-1,6	medium_impact	2,48	neutral	0,69	damaging	0,2	deleterious	2,28	18,06	0,51	0,6	neutral	0,5	disease	0,58	neutral	0,33	neutral	0,46	1	deleterious	0,99	neutral	0,08	deleterious	4	deleterious	0,56	low_impact	-1,53	medium_impact	-0,75	medium_impact	1,19	0,86	0,9	5,85	15,28	N	0,33	N	0,76	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6408	6408	A	C	MI.2953	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	505	169	I	L	Atc/Ctc	-5,89	0	0	benign	0,02	neutral	0,25	neutral	2,97	neutral	0,81	neutral	-0,87	neutral_impact	0,71	neutral	0,67	neutral	0,28	deleterious	0,73	9,05	0,37	0,55	neutral	0,17	neutral	0,4	neutral	0,25	neutral	0,45	1	neutral	0,74	deleterious	0,62	neutral	-6	neutral	0,12	medium_impact	0,83	medium_impact	-0,07	medium_impact	-0,44	0,68	0,9	6,24	8,75	N	0,4	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6408	6408	A	T	MI.2954	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	505	169	I	F	Atc/Ttc	-5,89	0	0	benign	0,24	neutral	0,17	neutral	2,77	neutral	-0,66	neutral	-2,21	low_impact	1,56	neutral	0,63	damaging	0,14	neutral	0,94	10,33	0,39	0,55	neutral	0,39	disease	0,55	neutral	0,26	neutral	0,36	3	neutral	0,8	neutral	0,47	neutral	-6	neutral	0,35	medium_impact	-0,29	medium_impact	-0,19	medium_impact	0,34	0,71	0,9	6,24	8,75	N	0,37	N	0,85	polymorphism	0,98	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6408	6408	A	G	MI.2955	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	505	169	I	V	Atc/Gtc	-5,89	0	0	benign	0	deleterious	0,04	neutral	2,86	neutral	0,11	neutral	-0,66	low_impact	1,8	neutral	0,69	neutral	0,62	neutral	1,04	10,89	0,61	0,65	neutral	0,25	neutral	0,43	neutral	0,43	neutral	0,44	1	neutral	0,96	deleterious	0,52	neutral	-2	neutral	0,13	high_impact	2,07	medium_impact	-0,58	medium_impact	0,56	0,62	0,9	6,24	8,75	N	0,51	P	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6409	6409	T	C	MI.2956	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	506	169	I	T	aTc/aCc	5,45	1	0	benign	0,22	neutral	0,05	neutral	2,76	neutral	-1,58	deleterious	-3,32	medium_impact	3,13	neutral	0,64	damaging	0,18	neutral	1,63	14,02	0,45	0,55	neutral	0,41	disease	0,73	disease	0,53	disease	0,58	2	neutral	0,94	neutral	0,42	neutral	-3	neutral	0,27	medium_impact	-0,24	medium_impact	-0,52	medium_impact	1,79	0,59	0,9	6,24	8,75	P	0,52	P	0,76	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6409	6409	T	A	MI.2957	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	506	169	I	N	aTc/aAc	5,45	1	0	possibly_damaging	0,81	neutral	0,11	neutral	2,68	deleterious	-3,25	deleterious	-4,81	medium_impact	3,4	neutral	0,61	damaging	0,13	deleterious	4,17	23,8	0,34	0,55	neutral	0,47	disease	0,81	neutral	0,43	disease	0,62	2	neutral	0,93	neutral	0,15	NA	0	deleterious	0,68	low_impact	-1,35	medium_impact	-0,31	high_impact	2,04	0,7	0,9	6,24	8,75	P	0,49	N	0,94	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6409	6409	T	G	MI.2958	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	506	169	I	S	aTc/aGc	5,45	1	0	possibly_damaging	0,49	deleterious	0,02	neutral	2,72	neutral	-2	deleterious	-3,96	medium_impact	2,99	neutral	0,66	damaging	0,16	deleterious	3,76	23,4	0,36	0,55	neutral	0,42	disease	0,81	neutral	0,46	disease	0,53	1	neutral	0,98	neutral	0,27	deleterious	4	neutral	0,4	medium_impact	-0,74	medium_impact	-0,75	medium_impact	1,66	0,6	0,9	6,24	8,75	N	0,45	N	0,62	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6410	6410	C	G	MI.2959	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	507	169	I	M	atC/atG	7,53	1	0,03	possibly_damaging	0,49	neutral	0,13	neutral	2,72	neutral	-1,92	neutral	-1,3	low_impact	1,12	neutral	0,63	damaging	0,22	neutral	1,71	14,47	0,49	0,55	neutral	0,49	neutral	0,44	neutral	0,28	neutral	0,42	2	neutral	0,86	neutral	0,32	neutral	-3	neutral	0,29	medium_impact	-0,74	medium_impact	-0,27	medium_impact	-0,07	0,73	0,9	6,24	8,75	P	0,53	P	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8664	8664	A	T	MI.296	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	138	46	Q	H	caA/caT	6,84	1	0	probably_damaging	1	neutral	0,54	neutral	4,33	neutral	-2,21	deleterious	-4,67	medium_impact	3,27	neutral	0,82	damaging	0,13	deleterious	3,52	23,1	0,54	0,65	disease	0,84	disease	0,74	neutral	0,47	disease	0,61	2	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,33	medium_impact	1,71	0,78	0,9	49,56	8,75	N	0,47	N	0,95	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6410	6410	C	A	MI.2960	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	507	169	I	M	atC/atA	7,53	1	0,03	possibly_damaging	0,49	neutral	0,13	neutral	2,72	neutral	-1,92	neutral	-1,3	low_impact	1,12	neutral	0,63	damaging	0,22	deleterious	2,19	17,47	0,49	0,55	neutral	0,49	neutral	0,44	neutral	0,28	neutral	0,42	2	neutral	0,86	neutral	0,32	neutral	-3	neutral	0,29	medium_impact	-0,74	medium_impact	-0,27	medium_impact	-0,07	0,73	0,9	6,24	8,75	P	0,53	P	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6411	6411	A	T	MI.2961	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	508	170	N	Y	Aat/Tat	-5,42	0	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-2,44	deleterious	-6,87	high_impact	4,23	damaging	0,57	damaging	0,13	deleterious	3,66	23,2	0,36	0,55	disease	0,67	disease	0,89	disease	0,6	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,81	0,43	0,9	3,31	6,84	N	0,32	N	0,93	polymorphism	0,95	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6411	6411	A	C	MI.2962	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	508	170	N	H	Aat/Cat	-5,42	0	0	probably_damaging	1	deleterious	0	neutral	2,68	neutral	-2,07	deleterious	-4,3	high_impact	4,03	damaging	0,57	damaging	0,12	deleterious	3,01	22,3	0,53	0,6	neutral	0,48	disease	0,81	disease	0,61	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,62	0,48	0,9	3,31	6,84	N	0,28	N	0,83	polymorphism	0,99	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6411	6411	A	G	MI.2963	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	508	170	N	D	Aat/Gat	-5,42	0	0	probably_damaging	0,99	deleterious	0	neutral	2,69	neutral	-1,68	deleterious	-4,31	high_impact	4,78	damaging	0,55	damaging	0,14	deleterious	3,81	23,4	0,63	0,65	neutral	0,43	disease	0,78	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-2,64	low_impact	-1,48	high_impact	3,32	0,48	0,9	3,31	6,84	P	0,59	P	0,92	polymorphism	0,99	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6412	6412	A	T	MI.2964	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	509	170	N	I	aAt/aTt	7,07	1	0	probably_damaging	1	deleterious	0,03	neutral	2,66	deleterious	-3,11	deleterious	-7,72	high_impact	4,23	damaging	0,58	damaging	0,12	deleterious	3,96	23,6	0,38	0,55	disease	0,6	disease	0,92	disease	0,59	disease	0,68	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,83	low_impact	-3,58	medium_impact	-0,65	high_impact	2,81	0,32	0,9	3,31	6,84	N	0,47	N	0,98	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6412	6412	A	C	MI.2965	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	509	170	N	T	aAt/aCt	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-1,23	deleterious	-5,15	medium_impact	3,38	damaging	0,59	damaging	0,13	deleterious	3,4	23	0,51	0,6	neutral	0,27	disease	0,87	disease	0,57	disease	0,67	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,02	0,51	0,9	3,31	6,84	N	0,43	N	0,59	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6412	6412	A	G	MI.2966	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	509	170	N	S	aAt/aGt	7,07	1	0	probably_damaging	0,98	neutral	0,06	neutral	2,74	neutral	-0,79	deleterious	-4,29	high_impact	3,56	damaging	0,52	damaging	0,16	deleterious	3,07	22,4	0,68	0,7	neutral	0,36	disease	0,81	disease	0,57	disease	0,56	1	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,78	low_impact	-2,35	medium_impact	-0,47	high_impact	2,19	0,33	0,9	3,31	6,84	P	0,51	P	0,79	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6413	6413	T	G	MI.2967	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	510	170	N	K	aaT/aaG	8,69	1	0,05	probably_damaging	1	deleterious	0	neutral	2,94	neutral	0,9	deleterious	-5,15	medium_impact	3,34	damaging	0,53	damaging	0,12	deleterious	3,95	23,6	0,59	0,65	neutral	0,21	disease	0,88	disease	0,56	disease	0,65	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	medium_impact	1,99	0,51	0,9	3,31	6,84	N	0,46	N	0,92	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6413	6413	T	A	MI.2968	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	510	170	N	K	aaT/aaA	8,69	1	0,05	probably_damaging	1	deleterious	0	neutral	2,94	neutral	0,9	deleterious	-5,15	medium_impact	3,34	damaging	0,53	damaging	0,12	deleterious	4,27	24	0,59	0,65	neutral	0,21	disease	0,88	disease	0,56	disease	0,65	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	medium_impact	1,99	0,51	0,9	3,31	6,84	P	0,49	N	0,92	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6414	6414	A	C	MI.2969	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	511	171	M	L	Ata/Cta	-5,42	0	0	probably_damaging	0,95	neutral	0,09	neutral	2,86	neutral	-1,04	deleterious	-2,5	low_impact	1,9	neutral	0,65	damaging	0,07	deleterious	3,08	22,5	0,53	0,6	neutral	0,23	disease	0,73	neutral	0,45	neutral	0,2	6	deleterious	0,98	neutral	0,07	neutral	-2	deleterious	0,7	low_impact	-1,96	medium_impact	-0,37	medium_impact	0,66	0,59	0,9	3,51	6,93	N	0,24	N	0,61	polymorphism	0,56	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8665	8665	C	G	MI.297	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	139	47	Q	E	Caa/Gaa	0,59	0,06	0	benign	0,11	neutral	0,91	neutral	4,67	neutral	1,9	neutral	-1,52	neutral_impact	-1,16	neutral	0,87	neutral	0,59	neutral	-1,24	0,01	0,61	0,7	disease	0,51	neutral	0,32	neutral	0,37	neutral	0,26	5	neutral	0,03	deleterious	0,9	neutral	-6	neutral	0,23	medium_impact	0,11	medium_impact	0,86	low_impact	-2,09	0,71	0,9	22,12	21,76	N	0,26	N	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6414	6414	A	G	MI.2970	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	511	171	M	V	Ata/Gta	-5,42	0	0	probably_damaging	0,97	neutral	0,05	neutral	2,81	neutral	-1,85	deleterious	-3,39	high_impact	3,9	damaging	0,59	damaging	0,07	deleterious	2,61	20,3	0,54	0,6	disease	0,56	disease	0,81	disease	0,72	disease	0,7	4	deleterious	0,99	neutral	0,04	deleterious	2	deleterious	0,82	low_impact	-2,18	medium_impact	-0,52	high_impact	2,5	0,57	0,9	3,51	6,93	N	0,29	N	0,88	polymorphism	0,51	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6414	6414	A	T	MI.2971	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	511	171	M	L	Ata/Tta	-5,42	0	0	probably_damaging	0,95	neutral	0,09	neutral	2,86	neutral	-1,04	deleterious	-2,5	low_impact	1,9	neutral	0,65	damaging	0,07	deleterious	3,16	22,6	0,53	0,6	neutral	0,23	disease	0,73	neutral	0,45	neutral	0,2	6	deleterious	0,98	neutral	0,07	neutral	-2	deleterious	0,7	low_impact	-1,96	medium_impact	-0,37	medium_impact	0,66	0,59	0,9	3,51	6,93	N	0,24	N	0,61	polymorphism	0,56	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6415	6415	T	A	MI.2972	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	512	171	M	K	aTa/aAa	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,76	deleterious	-3,08	deleterious	-5,13	high_impact	5,09	damaging	0,57	damaging	0,05	deleterious	3,87	23,5	0,21	0,55	disease	0,89	disease	0,89	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,91	low_impact	-2,64	low_impact	-1,48	high_impact	3,6	0,38	0,9	3,51	6,93	P	0,73	P	0,93	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6415	6415	T	C	MI.2973	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	512	171	M	T	aTa/aCa	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,83	neutral	-1,45	deleterious	-5,1	high_impact	4,4	neutral	0,61	damaging	0,11	deleterious	2,94	22	0,49	0,55	disease	0,78	disease	0,87	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,64	low_impact	-1,48	high_impact	2,96	0,38	0,9	3,51	6,93	P	0,5	N	0,79	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6416	6416	A	C	MI.2974	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	513	171	M	I	atA/atC	5,91	1	0	probably_damaging	0,98	deleterious	0	neutral	2,79	neutral	-2,22	deleterious	-3,38	high_impact	4,12	damaging	0,53	damaging	0,1	deleterious	3,27	22,8	0,54	0,6	disease	0,53	disease	0,81	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,35	low_impact	-1,48	high_impact	2,71	0,66	0,9	3,51	6,93	P	0,49	N	0,87	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6416	6416	A	T	MI.2975	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	513	171	M	I	atA/atT	5,91	1	0	probably_damaging	0,98	deleterious	0	neutral	2,79	neutral	-2,22	deleterious	-3,38	high_impact	4,12	damaging	0,53	damaging	0,1	deleterious	3,35	22,9	0,54	0,6	disease	0,53	disease	0,81	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,35	low_impact	-1,48	high_impact	2,71	0,66	0,9	3,51	6,93	P	0,52	P	0,87	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6417	6417	A	G	MI.2976	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	514	172	K	E	Aaa/Gaa	-0,1	0,1	0	probably_damaging	1	deleterious	0	neutral	2,54	neutral	-2,37	neutral	-1,89	medium_impact	3,42	damaging	0,53	damaging	0,08	deleterious	4	23,6	0,43	0,55	neutral	0,37	disease	0,75	disease	0,55	disease	0,68	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,06	0,72	0,9	2,92	6,73	N	0,34	N	0,75	disease_causing	0,86	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6417	6417	A	C	MI.2977	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	514	172	K	Q	Aaa/Caa	-0,1	0,1	0	probably_damaging	1	deleterious	0,01	neutral	2,55	neutral	-2,24	neutral	-1,19	medium_impact	2,73	damaging	0,54	damaging	0,07	deleterious	3,38	22,9	0,38	0,55	neutral	0,43	disease	0,51	neutral	0,5	neutral	0,5	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,42	0,63	0,9	2,92	6,73	N	0,33	N	0,64	disease_causing	0,79	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6418	6418	A	C	MI.2978	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	515	172	K	T	aAa/aCa	8,69	1	0	probably_damaging	1	deleterious	0,02	neutral	2,54	neutral	-2,43	deleterious	-2,82	medium_impact	3,08	damaging	0,52	damaging	0,07	deleterious	3,53	23,1	0,32	0,55	neutral	0,49	disease	0,58	neutral	0,49	neutral	0,49	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,77	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,75	0,46	0,9	2,92	6,73	P	0,47	N	0,76	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6418	6418	A	T	MI.2979	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	515	172	K	M	aAa/aTa	8,69	1	0	probably_damaging	1	deleterious	0,01	neutral	2,48	deleterious	-4,83	deleterious	-2,71	medium_impact	2,27	damaging	0,56	damaging	0,06	deleterious	3,77	23,4	0,28	0,55	disease	0,75	disease	0,56	neutral	0,37	neutral	0,5	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,58	medium_impact	-0,92	medium_impact	1	0,48	0,9	2,92	6,73	P	0,45	N	0,89	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8665	8665	C	A	MI.298	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	139	47	Q	K	Caa/Aaa	0,59	0,06	0	benign	0,04	neutral	1	neutral	4,41	neutral	0,18	neutral	-1,78	neutral_impact	-0,7	neutral	0,83	neutral	0,44	neutral	-0,18	1,23	0,63	0,7	neutral	0,31	neutral	0,33	neutral	0,21	neutral	0,44	1	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,21	medium_impact	0,55	high_impact	1,98	low_impact	-1,7	0,67	0,9	22,12	21,76	N	0,24	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6419	6419	A	C	MI.2980	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	516	172	K	N	aaA/aaC	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,52	neutral	-2,89	neutral	-2	medium_impact	2,19	damaging	0,53	damaging	0,06	deleterious	3,78	23,4	0,53	0,6	neutral	0,48	disease	0,61	neutral	0,38	neutral	0,47	1	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	medium_impact	0,92	0,57	0,9	2,92	6,73	P	0,48	N	0,76	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6419	6419	A	T	MI.2981	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	516	172	K	N	aaA/aaT	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,52	neutral	-2,89	neutral	-2	medium_impact	2,19	damaging	0,53	damaging	0,06	deleterious	3,85	23,4	0,53	0,6	neutral	0,48	disease	0,61	neutral	0,38	neutral	0,47	1	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	medium_impact	0,92	0,57	0,9	2,92	6,73	P	0,5	N	0,76	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6420	6420	C	G	MI.2982	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	517	173	P	A	Ccc/Gcc	1,75	1	0	probably_damaging	1	neutral	0,27	neutral	3	neutral	2,11	neutral	-0,64	neutral_impact	0,2	neutral	0,68	damaging	0,24	neutral	1,59	13,78	0,33	0,55	neutral	0,2	neutral	0,1	neutral	0,11	neutral	0,27	5	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,66	low_impact	-3,58	medium_impact	-0,05	medium_impact	-0,91	0,44	0,9	4,87	7,81	P	0,53	P	0,76	disease_causing	0,94	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6420	6420	C	T	MI.2983	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	517	173	P	S	Ccc/Tcc	1,75	1	0	probably_damaging	1	neutral	0,75	neutral	2,86	neutral	0,39	neutral	-0,22	neutral_impact	-0,12	neutral	0,66	neutral	0,29	neutral	1,52	13,4	0,36	0,55	neutral	0,23	neutral	0,17	neutral	0,1	neutral	0,29	4	deleterious	1	neutral	0,38	neutral	-2	deleterious	0,66	low_impact	-3,58	medium_impact	0,46	low_impact	-1,21	0,2	0,9	4,87	7,81	N	0,4	N	0,85	disease_causing	0,96	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6420	6420	C	A	MI.2984	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	517	173	P	T	Ccc/Acc	1,75	1	0	probably_damaging	1	neutral	0,17	neutral	2,84	neutral	0,94	neutral	-0,58	low_impact	0,87	neutral	0,67	damaging	0,14	deleterious	2,39	18,74	0,26	0,55	neutral	0,16	neutral	0,26	neutral	0,11	neutral	0,43	1	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,66	low_impact	-3,58	medium_impact	-0,19	medium_impact	-0,3	0,39	0,9	4,87	7,81	N	0,49	N	0,8	disease_causing	0,96	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6421	6421	C	A	MI.2985	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	518	173	P	H	cCc/cAc	3,6	1	0	probably_damaging	1	deleterious	0,03	neutral	2,78	neutral	-1,08	neutral	-1,88	medium_impact	2,08	neutral	0,69	damaging	0,1	deleterious	4,04	23,7	0,29	0,55	neutral	0,46	neutral	0,41	neutral	0,4	neutral	0,46	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,72	low_impact	-3,58	medium_impact	-0,65	medium_impact	0,82	0,34	0,9	4,87	7,81	N	0,43	N	0,81	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6421	6421	C	G	MI.2986	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	518	173	P	R	cCc/cGc	3,6	1	0	probably_damaging	1	deleterious	0,02	neutral	2,88	neutral	0,53	neutral	-2	medium_impact	2,65	neutral	0,65	damaging	0,09	deleterious	3,56	23,1	0,26	0,55	neutral	0,22	disease	0,63	neutral	0,46	neutral	0,49	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,71	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,35	0,38	0,9	4,87	7,81	N	0,37	N	0,9	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6421	6421	C	T	MI.2987	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	518	173	P	L	cCc/cTc	3,6	1	0	probably_damaging	1	neutral	0,07	neutral	2,81	neutral	-0,55	neutral	-1,82	low_impact	1,53	neutral	0,65	damaging	0,13	deleterious	4,24	23,9	0,31	0,55	neutral	0,39	neutral	0,42	neutral	0,26	neutral	0,48	0	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	-0,43	medium_impact	0,31	0,69	0,9	4,87	7,81	P	0,48	N	0,87	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6423	6423	C	A	MI.2988	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	520	174	P	T	Cct/Act	-7,97	0	0	probably_damaging	1	neutral	0,22	neutral	2,75	neutral	-1,67	neutral	-0,56	low_impact	1,24	damaging	0,55	damaging	0,1	deleterious	2,32	18,31	0,44	0,55	neutral	0,28	neutral	0,28	neutral	0,29	neutral	0,44	1	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,66	low_impact	-3,58	medium_impact	-0,11	medium_impact	0,05	0,66	0,9	1,56	6,69	N	0,37	N	0,8	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6423	6423	C	T	MI.2989	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	520	174	P	S	Cct/Tct	-7,97	0	0	probably_damaging	1	neutral	0,33	neutral	2,73	neutral	-1,58	neutral	-0,16	neutral_impact	0,32	damaging	0,54	damaging	0,08	deleterious	2,48	19,32	0,48	0,55	neutral	0,43	neutral	0,24	neutral	0,16	neutral	0,45	1	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,68	low_impact	-3,58	medium_impact	0,02	medium_impact	-0,8	0,31	0,9	1,56	6,69	N	0,43	N	0,85	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8666	8666	A	T	MI.299	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	140	47	Q	L	cAa/cTa	-0,33	0	0	benign	0,11	neutral	0,6	neutral	4,34	neutral	-0,85	deleterious	-3,19	neutral_impact	-0,82	neutral	0,85	neutral	0,77	deleterious	0,08	3,35	0,37	0,65	neutral	0,35	neutral	0,24	neutral	0,24	neutral	0,44	1	neutral	0,3	deleterious	0,75	neutral	-6	neutral	0,29	medium_impact	0,11	medium_impact	0,39	low_impact	-1,8	0,3	0,9	22,12	21,76	N	0,29	N	0,81	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6423	6423	C	G	MI.2990	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	520	174	P	A	Cct/Gct	-7,97	0	0	probably_damaging	0,99	neutral	0,13	neutral	2,71	neutral	-1,51	neutral	-0,9	low_impact	1,89	damaging	0,57	damaging	0,24	neutral	1,76	14,76	0,39	0,55	neutral	0,43	neutral	0,18	neutral	0,31	neutral	0,31	4	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,67	low_impact	-2,64	medium_impact	-0,27	medium_impact	0,65	0,66	0,9	1,56	6,69	N	0,42	N	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6424	6424	C	G	MI.2991	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	521	174	P	R	cCt/cGt	3,6	0,99	0	probably_damaging	1	neutral	0,05	neutral	2,71	neutral	-1,53	neutral	-0,73	medium_impact	2,76	damaging	0,54	damaging	0,06	deleterious	2,45	19,15	0,4	0,55	disease	0,51	disease	0,6	neutral	0,47	disease	0,51	0	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,75	low_impact	-3,58	medium_impact	-0,52	medium_impact	1,45	0,57	0,9	1,56	6,69	N	0,43	N	0,9	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6424	6424	C	A	MI.2992	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	521	174	P	H	cCt/cAt	3,6	0,99	0	probably_damaging	1	deleterious	0,03	neutral	2,68	deleterious	-3,1	neutral	-0,97	medium_impact	2,27	damaging	0,56	damaging	0,07	deleterious	2,79	21,3	0,44	0,55	disease	0,67	neutral	0,41	neutral	0,27	disease	0,63	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,73	low_impact	-3,58	medium_impact	-0,65	medium_impact	1	0,51	0,9	1,56	6,69	N	0,44	N	0,81	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6424	6424	C	T	MI.2993	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	521	174	P	L	cCt/cTt	3,6	0,99	0	probably_damaging	1	neutral	0,05	neutral	2,67	neutral	-2,25	neutral	-1,78	low_impact	1,46	damaging	0,57	damaging	0,08	deleterious	3,05	22,4	0,34	0,55	disease	0,63	neutral	0,42	neutral	0,32	disease	0,61	2	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,73	low_impact	-3,58	medium_impact	-0,52	medium_impact	0,25	0,73	0,9	1,56	6,69	N	0,45	N	0,87	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6426	6426	G	T	MI.2994	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	523	175	A	S	Gcc/Tcc	-20	0	0	probably_damaging	1	neutral	0,64	neutral	3,01	neutral	-0,36	neutral	0,46	neutral_impact	-1,62	neutral	0,63	damaging	0,26	deleterious	0,79	9,39	0,54	0,6	neutral	0,34	neutral	0,27	neutral	0,17	neutral	0,45	1	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,69	low_impact	-3,58	medium_impact	0,33	low_impact	-2,6	0,81	0,9	2,14	7,35	N	0,39	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6426	6426	G	A	MI.2995	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	523	175	A	T	Gcc/Acc	-20	0	0	probably_damaging	1	neutral	0,16	neutral	2,98	neutral	-0,82	neutral	-0,89	neutral_impact	-0,46	neutral	0,66	damaging	0,24	neutral	1,19	11,72	0,63	0,65	neutral	0,41	neutral	0,36	neutral	0,29	neutral	0,48	0	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,71	low_impact	-3,58	medium_impact	-0,21	low_impact	-1,52	0,71	0,9	2,14	7,35	N	0,37	N	0,2	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6426	6426	G	C	MI.2996	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	523	175	A	P	Gcc/Ccc	-20	0	0	probably_damaging	1	deleterious	0,02	neutral	2,95	neutral	-2,27	neutral	-1,55	neutral_impact	0,76	damaging	0,6	damaging	0,12	deleterious	3,74	23,3	0,34	0,55	disease	0,68	disease	0,75	neutral	0,28	disease	0,53	1	deleterious	1	neutral	0,01	deleterious	2	deleterious	0,84	low_impact	-3,58	medium_impact	-0,75	medium_impact	-0,4	0,68	0,9	2,14	7,35	N	0,28	N	0,85	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6427	6427	C	A	MI.2997	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	524	175	A	D	gCc/gAc	2,44	0,98	0	probably_damaging	1	neutral	0,07	neutral	2,98	neutral	-0,62	neutral	-0,64	neutral_impact	0,22	neutral	0,61	damaging	0,12	deleterious	4,31	24	0,28	0,55	disease	0,64	disease	0,68	neutral	0,37	neutral	0,48	0	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,8	low_impact	-3,58	medium_impact	-0,43	medium_impact	-0,9	0,54	0,9	2,14	7,35	N	0,43	N	0,89	disease_causing	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6427	6427	C	G	MI.2998	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	524	175	A	G	gCc/gGc	2,44	0,98	0	probably_damaging	0,99	neutral	0,91	neutral	3,27	neutral	1,95	neutral	2,81	neutral_impact	-3,02	neutral	0,64	damaging	0,21	neutral	-0,55	0,17	0,58	0,65	neutral	0,37	neutral	0,05	neutral	0,13	neutral	0,23	5	deleterious	0,99	neutral	0,46	neutral	-2	deleterious	0,63	low_impact	-2,64	medium_impact	0,75	low_impact	-3,89	0,69	0,9	2,14	7,35	N	0,39	N	0,56	disease_causing	0,91	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6427	6427	C	T	MI.2999	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	524	175	A	V	gCc/gTc	2,44	0,98	0	probably_damaging	1	deleterious	0,02	neutral	2,97	neutral	-1,69	neutral	-2,07	neutral_impact	-0,26	damaging	0,59	damaging	0,15	deleterious	2,74	21	0,51	0,6	disease	0,62	neutral	0,46	neutral	0,32	disease	0,6	2	deleterious	1	neutral	0,01	deleterious	2	deleterious	0,76	low_impact	-3,58	medium_impact	-0,75	low_impact	-1,34	0,66	0,9	2,14	7,35	N	0,48	N	0,75	disease_causing	0,92	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8528	8528	T	A	MI.3	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	2	1	M	K	aTg/aAg	5,68	1	0	possibly_damaging	0,8	deleterious	0	neutral	4,49	neutral	-0,95	deleterious	-4,89	NA	NA	neutral	0,61	damaging	0,09	deleterious	6,26	28,9	0,25	0,65	neutral	0,39	disease	0,57	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	3	deleterious	0,73	NA	NA	NA	NA	NA	NA	0,42	0,9	50	8,74	P	0,58	P	0,99	NA	NA	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8539	8539	C	G	MI.30	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	13	5	L	V	Ctg/Gtg	-0,33	0	0	probably_damaging	0,95	deleterious	0,04	neutral	4,23	neutral	-1,25	neutral	-2,26	medium_impact	2,93	neutral	0,8	neutral	0,5	deleterious	3,38	22,9	0,44	0,65	disease	0,5	neutral	0,33	disease	0,69	neutral	0,44	1	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,7	low_impact	-1,97	medium_impact	-0,49	medium_impact	1,41	0,62	0,9	50,44	8,42	N	0,39	N	0,81	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8666	8666	A	G	MI.300	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	140	47	Q	R	cAa/cGa	-0,33	0	0	benign	0,01	neutral	0,5	neutral	4,35	neutral	-0,77	neutral	-1,69	low_impact	1,7	neutral	0,98	neutral	0,82	neutral	-0,52	0,2	0,66	0,7	neutral	0,35	neutral	0,34	neutral	0,4	neutral	0,44	1	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,18	medium_impact	1,14	medium_impact	0,29	medium_impact	0,36	0,57	0,9	22,12	21,76	N	0,36	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6429	6429	A	G	MI.3000	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	526	176	M	V	Ata/Gta	-13,06	0	0	benign	0	neutral	0,22	neutral	2,71	neutral	-1,97	neutral	-1,99	medium_impact	2,62	neutral	0,74	neutral	0,86	deleterious	0,81	9,55	0,52	0,6	neutral	0,4	disease	0,73	neutral	0,47	neutral	0,42	2	neutral	0,78	deleterious	0,61	neutral	-3	neutral	0,22	high_impact	2,07	medium_impact	-0,11	medium_impact	1,32	0,27	0,9	8,58	22,89	N	0,41	N	0,05	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6429	6429	A	C	MI.3001	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	526	176	M	L	Ata/Cta	-13,06	0	0	benign	0	neutral	0,24	neutral	2,8	neutral	-1,53	neutral	-1,13	low_impact	1,35	neutral	0,72	neutral	0,94	deleterious	0,19	4,56	0,49	0,55	neutral	0,26	disease	0,58	neutral	0,4	neutral	0,38	2	neutral	0,76	deleterious	0,62	neutral	-6	neutral	0,17	high_impact	2,07	medium_impact	-0,09	medium_impact	0,15	0,41	0,9	8,58	22,89	N	0,46	N	0,4	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6429	6429	A	T	MI.3002	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	526	176	M	L	Ata/Tta	-13,06	0	0	benign	0	neutral	0,24	neutral	2,8	neutral	-1,53	neutral	-1,13	low_impact	1,35	neutral	0,72	neutral	0,94	deleterious	0,34	6,09	0,49	0,55	neutral	0,26	disease	0,58	neutral	0,4	neutral	0,38	2	neutral	0,76	deleterious	0,62	neutral	-6	neutral	0,17	high_impact	2,07	medium_impact	-0,09	medium_impact	0,15	0,41	0,9	8,58	22,89	N	0,46	N	0,4	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6430	6430	T	C	MI.3003	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	527	176	M	T	aTa/aCa	0,59	0,06	0	benign	0	deleterious	0,04	neutral	2,69	neutral	-2,79	deleterious	-3,89	high_impact	3,75	neutral	0,73	neutral	0,52	neutral	1,04	10,89	0,49	0,55	disease	0,52	disease	0,83	disease	0,7	disease	0,65	3	neutral	0,96	deleterious	0,52	deleterious	2	neutral	0,28	high_impact	2,07	medium_impact	-0,58	high_impact	2,36	0,2	0,9	8,58	22,89	N	0,43	N	0,69	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6430	6430	T	A	MI.3004	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	527	176	M	K	aTa/aAa	0,59	0,06	0	benign	0,06	deleterious	0,02	neutral	2,6	deleterious	-3,08	deleterious	-4,38	medium_impact	3,29	neutral	0,65	damaging	0,12	deleterious	2,11	16,94	0,26	0,55	disease	0,65	disease	0,88	disease	0,71	disease	0,68	4	neutral	0,98	deleterious	0,48	deleterious	1	neutral	0,35	medium_impact	0,37	medium_impact	-0,75	medium_impact	1,94	0,35	0,9	8,58	22,89	N	0,31	N	0,82	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6431	6431	A	C	MI.3005	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	528	176	M	I	atA/atC	4,76	0,72	0	benign	0	neutral	0,92	neutral	2,79	neutral	-2,02	neutral	-1,73	low_impact	1,7	neutral	0,74	neutral	0,95	deleterious	0,14	4,06	0,54	0,6	neutral	0,37	disease	0,56	neutral	0,43	neutral	0,38	2	neutral	0,07	deleterious	0,96	neutral	-6	neutral	0,2	high_impact	2,07	medium_impact	0,78	medium_impact	0,47	0,34	0,9	8,58	22,89	N	0,4	N	0,51	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6431	6431	A	T	MI.3006	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	528	176	M	I	atA/atT	4,76	0,72	0	benign	0	neutral	0,92	neutral	2,79	neutral	-2,02	neutral	-1,73	low_impact	1,7	neutral	0,74	neutral	0,95	deleterious	0,17	4,4	0,54	0,6	neutral	0,37	disease	0,56	neutral	0,43	neutral	0,38	2	neutral	0,07	deleterious	0,96	neutral	-6	neutral	0,2	high_impact	2,07	medium_impact	0,78	medium_impact	0,47	0,34	0,9	8,58	22,89	N	0,4	N	0,51	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6432	6432	A	C	MI.3007	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	529	177	T	P	Acc/Ccc	-3,57	0	0	benign	0,33	neutral	0,06	neutral	2,65	neutral	-1,75	neutral	-2,38	low_impact	1,92	neutral	0,62	neutral	0,58	deleterious	0,43	6,84	0,25	0,55	disease	0,66	disease	0,8	neutral	0,15	disease	0,61	2	neutral	0,93	neutral	0,37	neutral	-6	neutral	0,38	medium_impact	-0,47	medium_impact	-0,47	medium_impact	0,67	0,59	0,9	8,38	27,34	N	0,43	N	0,47	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6432	6432	A	T	MI.3008	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	529	177	T	S	Acc/Tcc	-3,57	0	0	benign	0	neutral	1	neutral	2,79	neutral	-0,72	neutral	0,05	neutral_impact	-0,1	neutral	0,81	neutral	1	neutral	-1,41	0	0,52	0,6	neutral	0,25	neutral	0,14	neutral	0,11	neutral	0,29	4	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,07	high_impact	1,86	low_impact	-1,19	0,63	0,9	8,38	27,34	N	0,4	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6432	6432	A	G	MI.3009	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	529	177	T	A	Acc/Gcc	-3,57	0	0	benign	0,04	deleterious	0,02	neutral	2,7	neutral	-1,6	neutral	-1,26	medium_impact	2,95	neutral	0,68	neutral	0,7	neutral	1,44	12,98	0,54	0,6	neutral	0,4	neutral	0,4	neutral	0,24	neutral	0,47	1	neutral	0,98	deleterious	0,49	deleterious	1	neutral	0,14	medium_impact	0,54	medium_impact	-0,75	medium_impact	1,63	0,35	0,9	8,38	27,34	P	0,51	P	0,05	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8666	8666	A	C	MI.301	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	140	47	Q	P	cAa/cCa	-0,33	0	0	possibly_damaging	0,47	neutral	0,28	neutral	4,3	neutral	-2,22	deleterious	-3,11	low_impact	1,36	neutral	0,68	neutral	0,31	deleterious	0,13	3,88	0,2	0,65	disease	0,71	disease	0,71	disease	0,56	disease	0,71	4	neutral	0,69	neutral	0,41	neutral	-3	deleterious	0,62	medium_impact	-0,71	medium_impact	0,06	medium_impact	0,07	0,58	0,9	22,12	21,76	N	0,26	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6433	6433	C	T	MI.3010	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	530	177	T	I	aCc/aTc	0,59	0,29	0	benign	0,33	deleterious	0,02	neutral	2,63	deleterious	-3,6	deleterious	-2,59	medium_impact	2,5	neutral	0,67	neutral	0,6	deleterious	1,91	15,62	0,48	0,55	disease	0,65	disease	0,66	neutral	0,19	neutral	0,49	0	neutral	0,98	neutral	0,35	deleterious	1	neutral	0,33	medium_impact	-0,47	medium_impact	-0,75	medium_impact	1,21	0,46	0,9	8,38	27,34	N	0,35	N	0,71	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6433	6433	C	G	MI.3011	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	530	177	T	S	aCc/aGc	0,59	0,29	0	benign	0	neutral	1	neutral	2,79	neutral	-0,72	neutral	0,05	neutral_impact	-0,1	neutral	0,81	neutral	1	neutral	-1,21	0,01	0,52	0,6	neutral	0,25	neutral	0,14	neutral	0,11	neutral	0,29	4	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,07	high_impact	1,86	low_impact	-1,19	0,63	0,9	8,38	27,34	N	0,32	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6433	6433	C	A	MI.3012	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	530	177	T	N	aCc/aAc	0,59	0,29	0	benign	0,13	neutral	0,24	neutral	2,7	neutral	-1,92	neutral	-1,05	low_impact	1,2	neutral	0,7	neutral	0,75	deleterious	0,51	7,54	0,64	0,7	neutral	0,46	disease	0,54	neutral	0,27	neutral	0,46	1	neutral	0,72	deleterious	0,56	neutral	-6	neutral	0,2	medium_impact	0,02	medium_impact	-0,09	medium_impact	0,01	0,7	0,9	8,38	27,34	N	0,43	N	0,23	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6435	6435	C	A	MI.3013	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	532	178	Q	K	Caa/Aaa	-6,35	0	0	probably_damaging	0,98	neutral	0,29	neutral	2,82	neutral	0,34	neutral	-0,51	neutral_impact	-0,2	damaging	0,6	damaging	0,12	deleterious	2,74	21	0,44	0,55	neutral	0,49	disease	0,51	disease	0,53	disease	0,51	0	deleterious	0,98	neutral	0,16	neutral	-2	deleterious	0,72	low_impact	-2,35	medium_impact	-0,02	low_impact	-1,28	0,4	0,9	1,56	7,91	N	0,29	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6435	6435	C	G	MI.3014	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	532	178	Q	E	Caa/Gaa	-6,35	0	0	probably_damaging	0,95	neutral	0,27	neutral	2,81	neutral	0,17	neutral	-0,91	neutral_impact	0,14	neutral	0,6	damaging	0,14	deleterious	1,9	15,57	0,47	0,55	disease	0,52	neutral	0,48	disease	0,53	disease	0,55	1	neutral	0,96	neutral	0,16	neutral	-2	deleterious	0,72	low_impact	-1,96	medium_impact	-0,05	medium_impact	-0,97	0,52	0,9	1,56	7,91	N	0,29	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6436	6436	A	C	MI.3015	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	533	178	Q	P	cAa/cCa	5,45	1	0	probably_damaging	0,99	neutral	0,21	neutral	2,79	neutral	-0,77	neutral	-1,32	neutral_impact	-1,4	neutral	0,61	damaging	0,2	deleterious	1,83	15,14	0,26	0,55	disease	0,62	disease	0,72	neutral	0,36	disease	0,53	1	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,82	low_impact	-2,64	medium_impact	-0,13	low_impact	-2,39	0,4	0,9	1,56	7,91	N	0,43	N	0,84	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6436	6436	A	G	MI.3016	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	533	178	Q	R	cAa/cGa	5,45	1	0	probably_damaging	0,98	neutral	0,34	neutral	2,79	neutral	-0,78	neutral	-0,55	neutral_impact	0,34	neutral	0,6	damaging	0,13	deleterious	2,21	17,58	0,52	0,6	disease	0,52	disease	0,61	disease	0,56	disease	0,69	4	deleterious	0,99	neutral	0,18	neutral	-2	deleterious	0,76	low_impact	-2,35	medium_impact	0,03	medium_impact	-0,79	0,29	0,9	1,56	7,91	N	0,45	N	0,76	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6436	6436	A	T	MI.3017	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	533	178	Q	L	cAa/cTa	5,45	1	0	probably_damaging	0,98	neutral	0,68	neutral	3,12	neutral	3,3	neutral	2,07	neutral_impact	-3,52	neutral	0,67	damaging	0,21	neutral	1,07	11,04	0,33	0,55	neutral	0,23	neutral	0,25	neutral	0,15	neutral	0,42	2	neutral	0,97	neutral	0,35	neutral	-2	deleterious	0,65	low_impact	-2,35	medium_impact	0,38	low_impact	-4,35	0,21	0,9	1,56	7,91	N	0,45	N	0,71	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6437	6437	A	C	MI.3018	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	534	178	Q	H	caA/caC	8,69	1	0	probably_damaging	1	neutral	0,55	neutral	2,78	neutral	-1,35	neutral	-0,52	neutral_impact	0,34	damaging	0,59	damaging	0,12	deleterious	2,1	16,88	0,52	0,6	neutral	0,37	neutral	0,39	disease	0,51	neutral	0,48	0	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	0,24	medium_impact	-0,79	0,46	0,9	1,56	7,91	N	0,46	N	0,7	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6437	6437	A	T	MI.3019	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	534	178	Q	H	caA/caT	8,69	1	0	probably_damaging	1	neutral	0,55	neutral	2,78	neutral	-1,35	neutral	-0,52	neutral_impact	0,34	damaging	0,59	damaging	0,12	deleterious	2,24	17,77	0,52	0,6	neutral	0,37	neutral	0,39	disease	0,51	neutral	0,48	0	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	0,24	medium_impact	-0,79	0,46	0,9	1,56	7,91	N	0,46	N	0,7	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8667	8667	A	C	MI.302	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	141	47	Q	H	caA/caC	-0,33	0	0	possibly_damaging	0,66	neutral	0,35	neutral	4,31	neutral	-1,92	deleterious	-2,54	low_impact	0,9	neutral	0,89	neutral	0,77	deleterious	1,92	15,69	0,68	0,75	disease	0,59	neutral	0,23	neutral	0,4	disease	0,54	1	neutral	0,72	neutral	0,35	neutral	-3	deleterious	0,59	low_impact	-1,03	medium_impact	0,14	medium_impact	-0,33	0,81	0,9	22,12	21,76	N	0,44	N	0,18	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6438	6438	T	C	MI.3020	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	535	179	Y	H	Tac/Cac	-0,33	0,1	0	probably_damaging	1	neutral	0,23	neutral	2,81	neutral	1,61	neutral	1,15	neutral_impact	-1,03	neutral	0,61	damaging	0,11	deleterious	2,35	18,49	0,61	0,65	neutral	0,33	neutral	0,28	neutral	0,18	neutral	0,45	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,69	low_impact	-3,58	medium_impact	-0,1	low_impact	-2,05	0,38	0,9	1,17	6,78	N	0,47	N	0,61	disease_causing	0,81	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6438	6438	T	G	MI.3021	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	535	179	Y	D	Tac/Gac	-0,33	0,1	0	probably_damaging	1	neutral	1	neutral	2,86	neutral	1,68	neutral	4,11	neutral_impact	-2,85	neutral	0,67	damaging	0,27	neutral	1,2	11,72	0,46	0,55	neutral	0,44	neutral	0,21	neutral	0,32	neutral	0,36	3	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,69	low_impact	-3,58	high_impact	1,86	low_impact	-3,73	0,44	0,9	1,17	6,78	N	0,25	N	0,98	disease_causing	0,97	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6438	6438	T	A	MI.3022	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	535	179	Y	N	Tac/Aac	-0,33	0,1	0	probably_damaging	1	neutral	0,93	neutral	2,87	neutral	1,73	neutral	1,74	neutral_impact	-1,11	neutral	0,64	damaging	0,12	deleterious	3,02	22,3	0,42	0,55	neutral	0,31	disease	0,58	neutral	0,28	neutral	0,44	1	deleterious	1	neutral	0,47	neutral	-2	deleterious	0,72	low_impact	-3,58	medium_impact	0,82	low_impact	-2,12	0,36	0,9	1,17	6,78	N	0,25	N	0,94	disease_causing	0,98	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6439	6439	A	T	MI.3023	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	536	179	Y	F	tAc/tTc	5,68	1	0	probably_damaging	0,98	neutral	0,1	neutral	2,83	neutral	1,65	neutral	-0,69	neutral_impact	-0,84	neutral	0,63	damaging	0,24	deleterious	2,03	16,39	0,35	0,55	neutral	0,24	neutral	0,45	neutral	0,23	neutral	0,48	1	deleterious	0,99	neutral	0,06	neutral	-2	deleterious	0,7	low_impact	-2,35	medium_impact	-0,34	low_impact	-1,88	0,3	0,9	1,17	6,78	P	0,57	P	0,5	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6439	6439	A	C	MI.3024	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	536	179	Y	S	tAc/tCc	5,68	1	0	probably_damaging	1	neutral	0,47	neutral	2,97	neutral	2,05	neutral	1,23	neutral_impact	-0,98	neutral	0,66	damaging	0,15	deleterious	2,46	19,21	0,34	0,55	neutral	0,34	disease	0,52	neutral	0,31	neutral	0,46	1	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,71	low_impact	-3,58	medium_impact	0,16	low_impact	-2	0,39	0,9	1,17	6,78	N	0,44	N	0,9	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6439	6439	A	G	MI.3025	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	536	179	Y	C	tAc/tGc	5,68	1	0	probably_damaging	1	neutral	0,05	neutral	2,78	neutral	-1,55	neutral	-1,48	low_impact	1,32	neutral	0,62	damaging	0,1	deleterious	3,35	22,9	0,37	0,55	disease	0,7	disease	0,71	neutral	0,44	neutral	0,49	0	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,79	low_impact	-3,58	medium_impact	-0,52	medium_impact	0,12	0,14	0,9	1,17	6,78	N	0,45	N	0,89	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6441	6441	C	G	MI.3026	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	538	180	Q	E	Caa/Gaa	-2,88	0	0	benign	0,24	deleterious	0,01	neutral	2,97	neutral	0,29	neutral	-1,32	medium_impact	2,97	neutral	0,62	damaging	0,13	deleterious	3,01	22,3	0,54	0,6	neutral	0,26	disease	0,66	disease	0,54	disease	0,64	3	deleterious	0,99	neutral	0,39	deleterious	1	neutral	0,3	medium_impact	-0,29	medium_impact	-0,92	medium_impact	1,64	0,59	0,9	4,68	15,51	N	0,33	N	0,72	disease_causing	0,84	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6441	6441	C	A	MI.3027	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	538	180	Q	K	Caa/Aaa	-2,88	0	0	benign	0,34	neutral	0,08	neutral	3,11	neutral	1,62	neutral	-0,41	neutral_impact	0,08	neutral	0,63	damaging	0,14	deleterious	2,8	21,4	0,58	0,65	neutral	0,21	neutral	0,41	neutral	0,17	neutral	0,45	1	neutral	0,91	neutral	0,37	neutral	-6	neutral	0,39	medium_impact	-0,49	medium_impact	-0,4	low_impact	-1,03	0,61	0,9	4,68	15,51	N	0,49	N	0,83	disease_causing	0,91	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6442	6442	A	G	MI.3028	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	539	180	Q	R	cAa/cGa	4,52	1	0	possibly_damaging	0,45	neutral	0,52	neutral	3,15	neutral	1,79	neutral	0,41	neutral_impact	-0,74	neutral	0,62	damaging	0,24	deleterious	0,73	9,04	0,63	0,65	neutral	0,22	neutral	0,25	neutral	0,19	neutral	0,43	1	neutral	0,45	deleterious	0,54	neutral	-3	neutral	0,38	medium_impact	-0,67	medium_impact	0,21	low_impact	-1,78	0,4	0,9	4,68	15,51	P	0,49	N	0,76	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6442	6442	A	T	MI.3029	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	539	180	Q	L	cAa/cTa	4,52	1	0	possibly_damaging	0,55	neutral	0,06	neutral	3,07	neutral	-1,15	deleterious	-3,75	low_impact	1,6	neutral	0,61	damaging	0,13	deleterious	3,75	23,3	0,36	0,55	neutral	0,34	disease	0,73	neutral	0,4	disease	0,51	0	neutral	0,94	neutral	0,26	neutral	-3	deleterious	0,51	medium_impact	-0,84	medium_impact	-0,47	medium_impact	0,38	0,25	0,9	4,68	15,51	N	0,47	N	0,71	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8667	8667	A	T	MI.303	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	141	47	Q	H	caA/caT	-0,33	0	0	possibly_damaging	0,66	neutral	0,35	neutral	4,31	neutral	-1,92	deleterious	-2,54	low_impact	0,9	neutral	0,89	neutral	0,77	deleterious	2,01	16,26	0,68	0,75	disease	0,59	neutral	0,23	neutral	0,4	disease	0,54	1	neutral	0,72	neutral	0,35	neutral	-3	deleterious	0,59	low_impact	-1,03	medium_impact	0,14	medium_impact	-0,33	0,81	0,9	22,12	21,76	N	0,44	N	0,18	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6442	6442	A	C	MI.3030	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	539	180	Q	P	cAa/cCa	4,52	1	0	possibly_damaging	0,9	deleterious	0,01	neutral	2,97	neutral	-1,51	deleterious	-3,33	medium_impact	3,31	damaging	0,57	damaging	0,12	deleterious	3,3	22,9	0,2	0,55	neutral	0,2	disease	0,88	disease	0,54	disease	0,76	5	deleterious	1	neutral	0,06	deleterious	4	deleterious	0,69	low_impact	-1,65	medium_impact	-0,92	medium_impact	1,96	0,46	0,9	4,68	15,51	N	0,4	N	0,84	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6443	6443	A	T	MI.3031	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	540	180	Q	H	caA/caT	8,69	1	0	benign	0,02	neutral	0,2	neutral	2,95	neutral	-1,39	neutral	-2,15	medium_impact	2,38	damaging	0,59	damaging	0,21	deleterious	3,47	23	0,59	0,65	neutral	0,37	disease	0,58	neutral	0,28	neutral	0,47	1	neutral	0,79	deleterious	0,59	neutral	-3	neutral	0,19	medium_impact	0,83	medium_impact	-0,14	medium_impact	1,1	0,59	0,9	4,68	15,51	P	0,6	P	0,7	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6443	6443	A	C	MI.3032	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	540	180	Q	H	caA/caC	8,69	1	0	benign	0,02	neutral	0,2	neutral	2,95	neutral	-1,39	neutral	-2,15	medium_impact	2,38	damaging	0,59	damaging	0,21	deleterious	3,25	22,8	0,59	0,65	neutral	0,37	disease	0,58	neutral	0,28	neutral	0,47	1	neutral	0,79	deleterious	0,59	neutral	-3	neutral	0,19	medium_impact	0,83	medium_impact	-0,14	medium_impact	1,1	0,59	0,9	4,68	15,51	P	0,6	P	0,7	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6444	6444	A	C	MI.3033	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	541	181	T	P	Acg/Ccg	0,82	0,99	0	probably_damaging	0,92	neutral	0,05	neutral	2,74	neutral	-2,32	neutral	-1,81	medium_impact	2,98	neutral	0,61	neutral	0,44	deleterious	3,29	22,8	0,17	0,55	disease	0,61	disease	0,76	neutral	0,45	disease	0,58	2	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,78	low_impact	-1,76	medium_impact	-0,52	medium_impact	1,65	0,51	0,9	6,63	13,64	N	0,45	N	0,92	disease_causing	0,93	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6444	6444	A	G	MI.3034	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	541	181	T	A	Acg/Gcg	0,82	0,99	0	benign	0,28	neutral	0,21	neutral	2,8	neutral	-0,06	neutral	-0,46	low_impact	1,82	neutral	0,66	neutral	0,55	neutral	1,48	13,19	0,53	0,6	neutral	0,3	neutral	0,31	neutral	0,49	neutral	0,46	1	neutral	0,75	neutral	0,47	neutral	-6	neutral	0,21	medium_impact	-0,37	medium_impact	-0,13	medium_impact	0,58	0,34	0,9	6,63	13,64	P	0,52	P	0,69	disease_causing	0,74	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6444	6444	A	T	MI.3035	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	541	181	T	S	Acg/Tcg	0,82	0,99	0	benign	0,42	deleterious	0,04	neutral	2,78	neutral	-0,56	neutral	-1	low_impact	1,48	neutral	0,66	neutral	0,54	neutral	1,32	12,38	0,49	0,55	neutral	0,34	neutral	0,34	neutral	0,35	neutral	0,46	1	neutral	0,95	neutral	0,31	neutral	-2	neutral	0,28	medium_impact	-0,62	medium_impact	-0,58	medium_impact	0,27	0,73	0,9	6,63	13,64	P	0,49	N	0,79	polymorphism	0,52	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6445	6445	C	A	MI.3036	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	542	181	T	K	aCg/aAg	6,84	1	0	probably_damaging	0,92	deleterious	0,04	neutral	2,75	neutral	-1,67	neutral	-1,35	medium_impact	2,98	neutral	0,63	neutral	0,44	deleterious	4,39	24,1	0,25	0,55	neutral	0,43	disease	0,6	disease	0,6	disease	0,71	4	deleterious	0,99	neutral	0,06	deleterious	5	deleterious	0,57	low_impact	-1,76	medium_impact	-0,58	medium_impact	1,65	0,65	0,9	6,63	13,64	P	0,54	P	0,88	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6445	6445	C	T	MI.3037	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	542	181	T	M	aCg/aTg	6,84	1	0	possibly_damaging	0,8	neutral	0,74	neutral	3,02	neutral	1,93	neutral	2,13	neutral_impact	-1,29	neutral	0,67	neutral	0,76	deleterious	0,84	9,7	0,38	0,55	neutral	0,21	neutral	0,07	neutral	0,15	neutral	0,24	5	neutral	0,76	deleterious	0,47	neutral	-3	neutral	0,22	low_impact	-1,32	medium_impact	0,45	low_impact	-2,29	0,68	0,9	6,63	13,64	P	0,54	P	0,96	disease_causing	1	0,01	rs879164161	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6447	6447	C	G	MI.3038	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	544	182	P	A	Ccc/Gcc	-8,89	0	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-3	deleterious	-6,14	high_impact	4,12	neutral	0,62	neutral	0,44	deleterious	3,05	22,4	0,29	0,55	disease	0,54	disease	0,57	disease	0,72	disease	0,64	3	deleterious	1	deleterious	0	deleterious	6	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,86	0,9	2,53	6,7	N	0,4	N	0,76	polymorphism	0,93	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6447	6447	C	T	MI.3039	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	544	182	P	S	Ccc/Tcc	-8,89	0	0	probably_damaging	1	neutral	0,32	neutral	2,64	deleterious	-3,06	deleterious	-5,91	low_impact	1,41	damaging	0,6	neutral	0,38	deleterious	3,8	23,4	0,41	0,55	neutral	0,5	disease	0,59	disease	0,52	neutral	0,43	1	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,76	low_impact	-3,58	medium_impact	0,01	medium_impact	0,2	0,42	0,9	2,53	6,7	N	0,26	N	0,85	polymorphism	0,89	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8668	8668	T	G	MI.304	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	142	48	W	G	Tga/Gga	-1,26	0	0	probably_damaging	0,99	neutral	0,37	neutral	4,28	neutral	-2,26	deleterious	-10,89	medium_impact	2,25	neutral	0,84	neutral	0,45	deleterious	3,76	23,3	0,3	0,65	neutral	0,45	disease	0,81	disease	0,73	disease	0,75	5	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,76	low_impact	-2,65	medium_impact	0,16	medium_impact	0,83	0,36	0,9	19,47	20,58	N	0,36	N	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6447	6447	C	A	MI.3040	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	544	182	P	T	Ccc/Acc	-8,89	0	0	probably_damaging	1	deleterious	0,01	neutral	2,6	deleterious	-3,72	deleterious	-6,1	medium_impact	2,64	damaging	0,57	neutral	0,31	deleterious	3,63	23,2	0,33	0,55	disease	0,59	disease	0,7	disease	0,55	disease	0,52	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,34	0,89	0,9	2,53	6,7	N	0,25	N	0,8	polymorphism	0,89	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6448	6448	C	G	MI.3041	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	545	182	P	R	cCc/cGc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-3,86	deleterious	-7,06	high_impact	5,01	damaging	0,56	neutral	0,3	deleterious	3,5	23,1	0,22	0,55	disease	0,77	disease	0,86	disease	0,82	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,53	0,84	0,9	2,53	6,7	P	0,68	P	0,9	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6448	6448	C	T	MI.3042	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	545	182	P	L	cCc/cTc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,64	deleterious	-4,2	deleterious	-7,91	high_impact	4,21	damaging	0,54	neutral	0,37	deleterious	4,35	24,1	0,33	0,55	disease	0,67	disease	0,8	disease	0,7	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,79	0,87	0,9	2,53	6,7	P	0,51	P	0,87	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6448	6448	C	A	MI.3043	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	545	182	P	H	cCc/cAc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-4,91	deleterious	-7,06	high_impact	4,66	damaging	0,57	neutral	0,29	deleterious	3,91	23,5	0,28	0,55	disease	0,85	disease	0,81	disease	0,8	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,2	0,77	0,9	2,53	6,7	P	0,58	P	0,81	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6450	6450	C	G	MI.3044	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	547	183	L	V	Ctc/Gtc	-13,98	0	0	probably_damaging	0,99	neutral	0,06	neutral	2,25	neutral	-2,2	deleterious	-2,61	high_impact	3,58	damaging	0,51	damaging	0,06	deleterious	3,38	22,9	0,37	0,55	neutral	0,47	disease	0,64	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,77	low_impact	-2,64	medium_impact	-0,47	high_impact	2,21	0,7	0,9	1,95	6,68	N	0,27	N	0,66	polymorphism	0,97	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6450	6450	C	T	MI.3045	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	547	183	L	F	Ctc/Ttc	-13,98	0	0	probably_damaging	1	deleterious	0	neutral	2,11	deleterious	-3,94	deleterious	-3,48	high_impact	4,86	damaging	0,5	damaging	0,04	deleterious	3,9	23,5	0,35	0,55	disease	0,57	disease	0,76	disease	0,66	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,39	0,74	0,9	1,95	6,68	P	0,58	P	0,87	polymorphism	0,88	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6450	6450	C	A	MI.3046	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	547	183	L	I	Ctc/Atc	-13,98	0	0	probably_damaging	1	deleterious	0	neutral	2,42	neutral	-1,23	neutral	-1,74	medium_impact	3,02	damaging	0,52	damaging	0,06	deleterious	4,02	23,6	0,31	0,55	neutral	0,29	disease	0,67	disease	0,55	disease	0,62	2	deleterious	1	neutral	0	deleterious	5	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	medium_impact	1,69	0,81	0,9	1,95	6,68	N	0,28	N	0,54	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6451	6451	T	G	MI.3047	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	548	183	L	R	cTc/cGc	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,06	deleterious	-6,86	deleterious	-5,22	high_impact	5,21	damaging	0,5	damaging	0,04	deleterious	4,14	23,8	0,14	0,55	disease	0,93	disease	0,89	disease	0,77	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,58	low_impact	-1,48	high_impact	3,71	0,58	0,9	1,95	6,68	P	0,59	P	0,9	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6451	6451	T	A	MI.3048	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	548	183	L	H	cTc/cAc	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,05	deleterious	-7,56	deleterious	-6,09	high_impact	5,21	damaging	0,54	damaging	0,05	deleterious	4,03	23,6	0,17	0,55	disease	0,95	disease	0,81	disease	0,75	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,71	0,68	0,9	1,95	6,68	P	0,52	P	0,83	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6451	6451	T	C	MI.3049	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	548	183	L	P	cTc/cCc	-0,33	0	0	probably_damaging	1	neutral	0,05	neutral	2,05	deleterious	-7,25	deleterious	-6,09	high_impact	4,05	damaging	0,39	damaging	0,05	deleterious	3,81	23,4	0,14	0,55	disease	0,94	disease	0,8	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,89	low_impact	-3,58	medium_impact	-0,52	high_impact	2,64	0,59	0,9	1,95	6,68	N	0,44	N	0,83	disease_causing	0,71	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8668	8668	T	C	MI.305	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	142	48	W	R	Tga/Cga	-1,26	0	0	probably_damaging	1	neutral	0,34	neutral	4,28	neutral	-2,46	deleterious	-11,72	medium_impact	3,06	neutral	0,92	neutral	0,36	deleterious	3,47	23	0,32	0,65	disease	0,56	disease	0,88	disease	0,73	disease	0,8	6	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	0,13	medium_impact	1,53	0,32	0,9	19,47	20,58	N	0,49	N	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	T8668C	LHON	+	-	Reported	1
chrM	6453	6453	T	C	MI.3050	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	550	184	F	L	Ttc/Ctc	-3,34	0	0	probably_damaging	0,99	deleterious	0,03	neutral	2,57	neutral	-1,32	deleterious	-4,93	medium_impact	2,73	damaging	0,56	damaging	0,19	deleterious	3,95	23,6	0,34	0,55	neutral	0,42	disease	0,73	disease	0,61	neutral	0,37	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,74	low_impact	-2,64	medium_impact	-0,65	medium_impact	1,42	0,77	0,9	4,48	7,68	N	0,28	N	0,83	polymorphism	0,91	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6453	6453	T	G	MI.3051	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	550	184	F	V	Ttc/Gtc	-3,34	0	0	probably_damaging	1	deleterious	0,03	neutral	2,59	neutral	-1,16	deleterious	-5,82	high_impact	4,4	neutral	0,63	damaging	0,16	deleterious	3,99	23,6	0,25	0,55	neutral	0,37	disease	0,85	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,76	low_impact	-3,58	medium_impact	-0,65	high_impact	2,96	0,64	0,9	4,48	7,68	N	0,39	N	0,84	polymorphism	0,84	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6453	6453	T	A	MI.3052	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	550	184	F	I	Ttc/Atc	-3,34	0	0	probably_damaging	1	deleterious	0,03	neutral	2,48	neutral	-2,23	deleterious	-4,98	medium_impact	3,36	neutral	0,71	damaging	0,18	deleterious	4,34	24	0,21	0,55	neutral	0,48	disease	0,81	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,78	low_impact	-3,58	medium_impact	-0,65	high_impact	2	0,7	0,9	4,48	7,68	N	0,31	N	0,88	polymorphism	0,92	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6454	6454	T	A	MI.3053	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	551	184	F	Y	tTc/tAc	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,45	neutral	-2,88	neutral	-2,43	medium_impact	3,34	neutral	0,68	damaging	0,16	deleterious	4,24	23,9	0,21	0,55	disease	0,54	disease	0,75	disease	0,64	disease	0,55	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	medium_impact	1,99	0,7	0,9	4,48	7,68	P	0,53	P	0,59	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6454	6454	T	C	MI.3054	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	551	184	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-3,08	deleterious	-6,73	high_impact	4,05	neutral	0,75	damaging	0,2	deleterious	4,22	23,9	0,22	0,55	neutral	0,48	disease	0,84	disease	0,67	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,64	0,57	0,9	4,48	7,68	N	0,5	N	0,84	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6454	6454	T	G	MI.3055	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	551	184	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,4	deleterious	-4,66	deleterious	-6,71	high_impact	5,21	neutral	0,67	damaging	0,16	deleterious	4,07	23,7	0,21	0,55	disease	0,78	disease	0,85	disease	0,71	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,71	0,39	0,9	4,48	7,68	P	0,66	P	0,91	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6455	6455	C	A	MI.3056	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	552	184	F	L	ttC/ttA	7,53	1	0,18	probably_damaging	0,99	deleterious	0,03	neutral	2,57	neutral	-1,32	deleterious	-4,93	medium_impact	2,73	damaging	0,56	damaging	0,19	deleterious	4,64	24,5	0,34	0,55	neutral	0,42	disease	0,73	disease	0,61	neutral	0,37	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,74	low_impact	-2,64	medium_impact	-0,65	medium_impact	1,42	0,77	0,9	4,48	7,68	P	0,51	P	0,83	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6455	6455	C	G	MI.3057	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	552	184	F	L	ttC/ttG	7,53	1	0,18	probably_damaging	0,99	deleterious	0,03	neutral	2,57	neutral	-1,32	deleterious	-4,93	medium_impact	2,73	damaging	0,56	damaging	0,19	deleterious	4,28	24	0,34	0,55	neutral	0,42	disease	0,73	disease	0,61	neutral	0,37	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,74	low_impact	-2,64	medium_impact	-0,65	medium_impact	1,42	0,77	0,9	4,48	7,68	P	0,5	N	0,83	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6456	6456	G	T	MI.3058	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	553	185	V	F	Gtc/Ttc	-3,34	0	0	possibly_damaging	0,86	deleterious	0	neutral	2,57	neutral	-2,79	deleterious	-3,87	high_impact	4,75	neutral	0,6	neutral	0,48	deleterious	3,77	23,4	0,15	0,55	disease	0,62	disease	0,91	disease	0,62	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,77	low_impact	-1,5	low_impact	-1,48	high_impact	3,29	0,68	0,9	3,31	6,74	P	0,66	P	0,86	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6456	6456	G	C	MI.3059	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	553	185	V	L	Gtc/Ctc	-3,34	0	0	benign	0,06	deleterious	0	neutral	2,68	neutral	-1,33	neutral	-2,22	medium_impact	2,81	damaging	0,56	neutral	0,55	deleterious	3,46	23	0,36	0,55	neutral	0,36	disease	0,76	disease	0,55	disease	0,58	2	deleterious	1	deleterious	0,47	deleterious	1	neutral	0,23	medium_impact	0,37	low_impact	-1,48	medium_impact	1,5	0,63	0,9	3,31	6,74	N	0,39	N	0,55	disease_causing	0,99	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8669	8669	G	C	MI.306	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	143	48	W	S	tGa/tCa	2,44	0,98	0,01	probably_damaging	1	neutral	0,51	neutral	4,32	neutral	-1,16	deleterious	-11,64	low_impact	1,29	neutral	0,88	neutral	0,5	deleterious	3,84	23,4	0,31	0,65	neutral	0,47	disease	0,83	disease	0,61	disease	0,55	1	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,8	low_impact	-3,6	medium_impact	0,3	medium_impact	0,01	0,36	0,9	19,47	20,58	N	0,43	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6456	6456	G	A	MI.3060	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	553	185	V	I	Gtc/Atc	-3,34	0	0	benign	0,01	neutral	0,09	neutral	2,65	neutral	-1,01	neutral	-0,71	low_impact	1,78	damaging	0,56	neutral	0,59	deleterious	2,4	18,82	0,47	0,55	neutral	0,38	neutral	0,47	neutral	0,38	neutral	0,42	2	neutral	0,91	deleterious	0,54	neutral	-6	neutral	0,19	medium_impact	1,12	medium_impact	-0,37	medium_impact	0,55	0,84	0,9	3,31	6,74	N	0,51	P	0,24	disease_causing	0,96	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6457	6457	T	G	MI.3061	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	554	185	V	G	gTc/gGc	3,6	1	0	probably_damaging	0,94	deleterious	0	neutral	2,56	neutral	-2,88	deleterious	-5,41	high_impact	3,85	neutral	0,63	neutral	0,6	deleterious	3,77	23,4	0,15	0,55	disease	0,66	disease	0,8	disease	0,6	disease	0,55	1	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,77	low_impact	-1,88	low_impact	-1,48	high_impact	2,46	0,55	0,9	3,31	6,74	N	0,41	N	0,71	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6457	6457	T	A	MI.3062	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	554	185	V	D	gTc/gAc	3,6	1	0	probably_damaging	0,94	deleterious	0	neutral	2,51	deleterious	-4,38	deleterious	-5,34	high_impact	4,75	neutral	0,67	neutral	0,47	deleterious	4,41	24,1	0,08	0,55	disease	0,82	disease	0,9	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,82	low_impact	-1,88	low_impact	-1,48	high_impact	3,29	0,68	0,9	3,31	6,74	P	0,62	P	0,83	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6457	6457	T	C	MI.3063	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	554	185	V	A	gTc/gCc	3,6	1	0	possibly_damaging	0,66	deleterious	0,03	neutral	2,67	neutral	-0,58	deleterious	-2,94	medium_impact	2,52	neutral	0,63	neutral	0,6	deleterious	3,47	23	0,33	0,55	neutral	0,34	disease	0,53	neutral	0,41	neutral	0,44	1	neutral	0,97	neutral	0,19	deleterious	4	deleterious	0,52	low_impact	-1,03	medium_impact	-0,65	medium_impact	1,23	0,61	0,9	3,31	6,74	P	0,48	N	0,47	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6459	6459	T	C	MI.3064	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	556	186	W	R	Tga/Cga	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,28	deleterious	-5,57	deleterious	-12,13	high_impact	4,75	neutral	0,62	damaging	0,04	deleterious	3,51	23,1	0,19	0,55	disease	0,77	disease	0,92	disease	0,82	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,3	0,9	0,97	6,71	N	0,49	N	0,98	polymorphism	0,99	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6459	6459	T	G	MI.3065	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	556	186	W	G	Tga/Gga	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,29	deleterious	-5,28	deleterious	-11,27	high_impact	5,29	neutral	0,66	damaging	0,05	deleterious	3,83	23,4	0,17	0,55	disease	0,8	disease	0,86	disease	0,78	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,28	0,9	0,97	6,71	N	0,5	N	0,89	polymorphism	0,98	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6460	6460	G	C	MI.3066	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	557	186	W	S	tGa/tCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,3	deleterious	-4,73	deleterious	-12,12	high_impact	5,29	neutral	0,65	damaging	0,06	deleterious	4,05	23,7	0,17	0,55	disease	0,68	disease	0,91	disease	0,77	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,25	0,9	0,97	6,71	P	0,55	P	0,89	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6460	6460	G	T	MI.3067	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	557	186	W	L	tGa/tTa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,4	deleterious	-3,23	deleterious	-11,25	high_impact	4,6	neutral	0,69	damaging	0,04	deleterious	4,25	23,9	0,16	0,55	neutral	0,5	disease	0,86	disease	0,74	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,15	0,24	0,9	0,97	6,71	P	0,54	P	0,95	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6461	6461	A	C	MI.3068	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	558	186	W	C	tgA/tgC	9,15	1	0,01	probably_damaging	1	deleterious	0	neutral	2,28	deleterious	-6,19	deleterious	-11,26	high_impact	5,29	damaging	0,59	damaging	0,05	deleterious	4	23,6	0,2	0,55	disease	0,84	disease	0,9	disease	0,8	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,26	0,9	0,97	6,71	P	0,59	P	0,88	disease_causing	1	0,5	rs879168265	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6461	6461	A	T	MI.3069	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	558	186	W	C	tgA/tgT	9,15	1	0,01	probably_damaging	1	deleterious	0	neutral	2,28	deleterious	-6,19	deleterious	-11,26	high_impact	5,29	damaging	0,59	damaging	0,05	deleterious	4,09	23,7	0,2	0,55	disease	0,84	disease	0,9	disease	0,8	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,26	0,9	0,97	6,71	P	0,54	P	0,88	disease_causing	1	0,5	rs879168265	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8669	8669	G	T	MI.307	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	143	48	W	L	tGa/tTa	2,44	0,98	0,01	probably_damaging	0,99	neutral	0,82	neutral	4,55	neutral	-0,2	deleterious	-10,97	low_impact	1,25	neutral	0,84	neutral	0,54	deleterious	4,08	23,7	0,28	0,65	neutral	0,35	disease	0,7	disease	0,56	disease	0,52	0	deleterious	0,99	neutral	0,42	neutral	-2	deleterious	0,73	low_impact	-2,65	medium_impact	0,66	medium_impact	-0,03	0,25	0,9	19,47	20,58	N	0,32	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6462	6462	T	C	MI.3070	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	559	187	S	P	Tcc/Ccc	3,83	1	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-3,78	deleterious	-3,72	high_impact	4,9	damaging	0,44	damaging	0,06	deleterious	3,91	23,5	0,17	0,55	disease	0,65	disease	0,89	disease	0,68	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,43	0,77	0,9	2,14	6,81	P	0,69	P	0,91	disease_causing	0,99	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6462	6462	T	G	MI.3071	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	559	187	S	A	Tcc/Gcc	3,83	1	0	probably_damaging	0,99	neutral	0,39	neutral	2,74	neutral	-0,51	neutral	-1,34	low_impact	0,92	neutral	0,61	neutral	0,35	deleterious	2,29	18,12	0,34	0,55	neutral	0,26	neutral	0,23	neutral	0,31	neutral	0,39	2	deleterious	0,99	neutral	0,2	neutral	-2	deleterious	0,66	low_impact	-2,64	medium_impact	0,09	medium_impact	-0,25	0,8	0,9	2,14	6,81	P	0,51	P	0,35	disease_causing	0,89	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6462	6462	T	A	MI.3072	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	559	187	S	T	Tcc/Acc	3,83	1	0	probably_damaging	0,97	neutral	0,15	neutral	2,71	neutral	-0,88	neutral	-2,18	medium_impact	3,18	damaging	0,47	damaging	0,07	deleterious	3,72	23,3	0,3	0,55	neutral	0,3	disease	0,64	neutral	0,46	neutral	0,4	2	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,72	low_impact	-2,18	medium_impact	-0,23	medium_impact	1,84	0,85	0,9	2,14	6,81	P	0,53	P	0,43	disease_causing	0,97	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6463	6463	C	T	MI.3073	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	560	187	S	F	tCc/tTc	3,83	1	0	probably_damaging	1	deleterious	0	neutral	2,64	neutral	-2,02	deleterious	-4,59	high_impact	4,55	damaging	0,45	damaging	0,04	deleterious	4,09	23,7	0,17	0,55	disease	0,75	disease	0,9	disease	0,58	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,1	0,43	0,9	2,14	6,81	P	0,5	N	0,98	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6463	6463	C	G	MI.3074	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	560	187	S	C	tCc/tGc	3,83	1	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-4,39	deleterious	-3,51	high_impact	3,65	damaging	0,46	damaging	0,04	deleterious	3,47	23	0,23	0,55	disease	0,85	disease	0,83	neutral	0,47	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,27	0,75	0,9	2,14	6,81	N	0,42	N	0,85	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6463	6463	C	A	MI.3075	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	560	187	S	Y	tCc/tAc	3,83	1	0	probably_damaging	1	deleterious	0	neutral	2,68	neutral	-1,2	deleterious	-4,59	high_impact	4,9	damaging	0,46	damaging	0,05	deleterious	4,05	23,7	0,17	0,55	disease	0,53	disease	0,88	disease	0,59	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,43	0,77	0,9	2,14	6,81	P	0,65	P	0,92	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6465	6465	G	A	MI.3076	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	562	188	V	I	Gtc/Atc	-20	0	0	benign	0,02	neutral	0,18	neutral	2,87	neutral	0,44	neutral	-0,58	neutral_impact	0,7	neutral	0,65	neutral	0,79	deleterious	0,4	6,59	0,56	0,6	neutral	0,16	neutral	0,3	neutral	0,27	neutral	0,39	2	neutral	0,81	deleterious	0,58	neutral	-6	neutral	0,14	medium_impact	0,83	medium_impact	-0,17	medium_impact	-0,45	0,96	1	13,06	21,55	N	0,51	P	0,04	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6465	6465	G	C	MI.3077	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	562	188	V	L	Gtc/Ctc	-20	0	0	benign	0,06	neutral	0,11	neutral	2,91	neutral	0,69	neutral	-2,27	medium_impact	2,87	damaging	0,59	neutral	0,54	neutral	1,65	14,11	0,45	0,55	neutral	0,28	disease	0,8	neutral	0,32	neutral	0,49	0	neutral	0,88	deleterious	0,53	neutral	-3	neutral	0,24	medium_impact	0,37	medium_impact	-0,31	medium_impact	1,55	0,7	0,9	13,06	21,55	N	0,47	N	0,49	polymorphism	0,96	0,04	rs28414181	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6465	6465	G	T	MI.3078	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	562	188	V	F	Gtc/Ttc	-20	0	0	possibly_damaging	0,87	deleterious	0	neutral	2,72	neutral	-0,94	deleterious	-3,99	high_impact	4,04	neutral	0,61	neutral	0,46	deleterious	3,73	23,3	0,28	0,55	disease	0,58	disease	0,92	disease	0,56	disease	0,7	4	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,77	low_impact	-1,53	low_impact	-1,48	high_impact	2,63	0,8	0,9	13,06	21,55	N	0,39	N	0,87	polymorphism	0,71	0,13	rs28414181	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6466	6466	T	C	MI.3079	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	563	188	V	A	gTc/gCc	2,44	1	0	possibly_damaging	0,69	deleterious	0	neutral	2,84	neutral	0,27	deleterious	-3,35	high_impact	3,75	neutral	0,66	neutral	0,59	deleterious	3,28	22,8	0,39	0,55	neutral	0,46	disease	0,67	disease	0,53	disease	0,54	1	deleterious	1	neutral	0,16	deleterious	5	deleterious	0,6	low_impact	-1,08	low_impact	-1,48	high_impact	2,36	0,7	0,9	13,06	21,55	P	0,5	N	0,66	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8670	8670	A	T	MI.308	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	144	48	W	C	tgA/tgT	2,9	0,98	0	probably_damaging	1	neutral	0,18	neutral	4,27	deleterious	-3,14	deleterious	-11,03	medium_impact	3,26	neutral	0,93	neutral	0,54	deleterious	3,99	23,6	0,29	0,65	disease	0,8	disease	0,87	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,08	medium_impact	1,7	0,22	0,9	19,47	20,58	N	0,52	P	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6466	6466	T	A	MI.3080	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	563	188	V	D	gTc/gAc	2,44	1	0	probably_damaging	0,99	deleterious	0	neutral	2,63	deleterious	-4,35	deleterious	-5,83	high_impact	4,73	neutral	0,64	neutral	0,46	deleterious	4,42	24,2	0,11	0,55	disease	0,81	disease	0,91	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,64	low_impact	-1,48	high_impact	3,27	0,75	0,9	13,06	21,55	P	0,6	P	0,9	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6466	6466	T	G	MI.3081	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	563	188	V	G	gTc/gGc	2,44	1	0	probably_damaging	0,99	deleterious	0	neutral	2,64	deleterious	-3,2	deleterious	-5,94	high_impact	4,73	neutral	0,62	neutral	0,61	deleterious	3,8	23,4	0,22	0,55	disease	0,71	disease	0,84	disease	0,55	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	3,27	0,68	0,9	13,06	21,55	P	0,58	P	0,75	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6468	6468	C	G	MI.3082	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	565	189	L	V	Cta/Gta	-11,9	0	0	benign	0,18	neutral	0,09	neutral	2,56	neutral	-1,52	neutral	-0,84	low_impact	1,6	neutral	0,68	neutral	0,31	neutral	1,4	12,78	0,41	0,55	neutral	0,36	neutral	0,28	neutral	0,3	neutral	0,46	1	neutral	0,9	neutral	0,46	neutral	-6	neutral	0,24	medium_impact	-0,14	medium_impact	-0,37	medium_impact	0,38	0,58	0,9	8,58	17,61	N	0,45	N	0,32	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6468	6468	C	A	MI.3083	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	565	189	L	M	Cta/Ata	-11,9	0	0	benign	0,07	neutral	0,11	neutral	2,51	neutral	-2,02	neutral	-0,33	medium_impact	1,96	neutral	0,7	neutral	0,95	deleterious	0,7	8,81	0,3	0,55	disease	0,5	neutral	0,26	neutral	0,29	neutral	0,21	6	neutral	0,88	deleterious	0,52	neutral	-3	neutral	0,19	medium_impact	0,3	medium_impact	-0,31	medium_impact	0,71	0,58	0,9	8,58	17,61	P	0,5	N	0,05	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6469	6469	T	C	MI.3084	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	566	189	L	P	cTa/cCa	-4,96	0	0	possibly_damaging	0,72	deleterious	0,01	neutral	2,42	deleterious	-4,98	deleterious	-2,89	high_impact	3,71	neutral	0,6	damaging	0,1	deleterious	2,65	20,5	0,18	0,55	disease	0,73	disease	0,82	disease	0,64	disease	0,72	4	deleterious	0,99	neutral	0,15	deleterious	5	deleterious	0,67	low_impact	-1,14	medium_impact	-0,92	high_impact	2,33	0,56	0,9	8,58	17,61	N	0,25	N	0,82	disease_causing	0,74	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6469	6469	T	G	MI.3085	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	566	189	L	R	cTa/cGa	-4,96	0	0	possibly_damaging	0,65	deleterious	0,01	neutral	2,42	deleterious	-4,4	neutral	-2,12	high_impact	4,41	neutral	0,61	damaging	0,09	deleterious	2,8	21,4	0,17	0,55	disease	0,73	disease	0,8	disease	0,64	disease	0,71	4	deleterious	0,99	neutral	0,18	deleterious	5	deleterious	0,66	low_impact	-1,01	medium_impact	-0,92	high_impact	2,97	0,68	0,9	8,58	17,61	N	0,36	N	0,85	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6469	6469	T	A	MI.3086	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	566	189	L	Q	cTa/cAa	-4,96	0	0	possibly_damaging	0,72	deleterious	0,01	neutral	2,42	deleterious	-4,58	neutral	-2,1	high_impact	4,41	neutral	0,67	damaging	0,17	deleterious	2,79	21,3	0,2	0,55	disease	0,74	disease	0,65	neutral	0,5	neutral	0,5	0	deleterious	0,99	neutral	0,15	deleterious	5	deleterious	0,62	low_impact	-1,14	medium_impact	-0,92	high_impact	2,97	0,72	0,9	8,58	17,61	N	0,4	N	0,57	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6471	6471	A	C	MI.3087	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	568	190	I	L	Atc/Ctc	-0,33	0,13	0	benign	0,21	neutral	0,16	neutral	2,87	neutral	-0,34	neutral	-1,25	low_impact	1,5	neutral	0,62	neutral	0,63	deleterious	2,62	20,3	0,34	0,55	neutral	0,3	disease	0,52	neutral	0,32	neutral	0,44	1	neutral	0,81	deleterious	0,48	neutral	-6	neutral	0,19	medium_impact	-0,22	medium_impact	-0,21	medium_impact	0,29	0,4	0,9	5,85	29,77	N	0,49	N	0,61	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6471	6471	A	G	MI.3088	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	568	190	I	V	Atc/Gtc	-0,33	0,13	0	benign	0,01	neutral	0,64	neutral	2,9	neutral	0,39	neutral	-0,65	low_impact	1,07	neutral	0,72	neutral	0,9	neutral	1,76	14,76	0,54	0,6	neutral	0,18	neutral	0,14	neutral	0,28	neutral	0,23	5	neutral	0,34	deleterious	0,82	neutral	-6	neutral	0,12	medium_impact	1,12	medium_impact	0,33	medium_impact	-0,11	0,31	0,9	5,85	29,77	N	0,43	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6471	6471	A	T	MI.3089	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	568	190	I	F	Atc/Ttc	-0,33	0,13	0	possibly_damaging	0,8	neutral	0,13	neutral	2,79	neutral	-1,32	deleterious	-3,21	medium_impact	2,45	damaging	0,58	neutral	0,37	deleterious	3,75	23,3	0,3	0,55	disease	0,57	disease	0,7	neutral	0,38	disease	0,52	0	neutral	0,92	neutral	0,17	NA	0	deleterious	0,7	low_impact	-1,32	medium_impact	-0,27	medium_impact	1,16	0,49	0,9	5,85	29,77	N	0,38	N	0,85	polymorphism	0,62	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8670	8670	A	C	MI.309	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	144	48	W	C	tgA/tgC	2,9	0,98	0	probably_damaging	1	neutral	0,18	neutral	4,27	deleterious	-3,14	deleterious	-11,03	medium_impact	3,26	neutral	0,93	neutral	0,54	deleterious	3,84	23,4	0,29	0,65	disease	0,8	disease	0,87	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,08	medium_impact	1,7	0,22	0,9	19,47	20,58	N	0,51	P	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6472	6472	T	C	MI.3090	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	569	190	I	T	aTc/aCc	3,14	0,99	0	possibly_damaging	0,79	deleterious	0,01	neutral	2,79	neutral	-0,53	deleterious	-3,86	medium_impact	3,38	neutral	0,62	neutral	0,49	deleterious	3,45	23	0,45	0,55	disease	0,54	disease	0,54	neutral	0,4	neutral	0,46	1	deleterious	0,99	neutral	0,11	deleterious	4	deleterious	0,6	low_impact	-1,3	medium_impact	-0,92	high_impact	2,02	0,49	0,9	5,85	29,77	P	0,49	N	0,76	disease_causing	0,97	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6472	6472	T	G	MI.3091	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	569	190	I	S	aTc/aGc	3,14	0,99	0	probably_damaging	0,93	deleterious	0	neutral	2,73	neutral	-1,93	deleterious	-4,83	high_impact	3,98	neutral	0,65	neutral	0,43	deleterious	4,22	23,9	0,32	0,55	disease	0,71	disease	0,8	disease	0,54	disease	0,67	3	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,73	low_impact	-1,81	low_impact	-1,48	high_impact	2,58	0,38	0,9	5,85	29,77	N	0,44	N	0,62	disease_causing	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6472	6472	T	A	MI.3092	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	569	190	I	N	aTc/aAc	3,14	0,99	0	probably_damaging	0,98	deleterious	0	neutral	2,69	deleterious	-3,39	deleterious	-5,7	high_impact	3,75	neutral	0,64	neutral	0,42	deleterious	4,53	24,3	0,26	0,55	disease	0,84	disease	0,77	neutral	0,47	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,35	low_impact	-1,48	high_impact	2,36	0,48	0,9	5,85	29,77	N	0,45	N	0,94	disease_causing	0,99	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6473	6473	C	G	MI.3093	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	570	190	I	M	atC/atG	7,53	1	0	probably_damaging	0,93	deleterious	0	neutral	2,75	neutral	-2,05	neutral	-2,12	high_impact	3,9	neutral	0,65	neutral	0,45	deleterious	3,29	22,8	0,37	0,55	disease	0,66	disease	0,53	neutral	0,48	neutral	0,49	0	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,67	low_impact	-1,81	low_impact	-1,48	high_impact	2,5	0,61	0,9	5,85	29,77	P	0,53	P	0,76	disease_causing	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6473	6473	C	A	MI.3094	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	570	190	I	M	atC/atA	7,53	1	0	probably_damaging	0,93	deleterious	0	neutral	2,75	neutral	-2,05	neutral	-2,12	high_impact	3,9	neutral	0,65	neutral	0,45	deleterious	3,71	23,3	0,37	0,55	disease	0,66	disease	0,53	neutral	0,48	neutral	0,49	0	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,67	low_impact	-1,81	low_impact	-1,48	high_impact	2,5	0,61	0,9	5,85	29,77	P	0,53	P	0,76	disease_causing	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6474	6474	A	G	MI.3095	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	571	191	T	A	Aca/Gca	-4,27	0	0	probably_damaging	0,99	deleterious	0	neutral	2,7	neutral	-0,55	deleterious	-4,35	high_impact	4,01	neutral	0,73	damaging	0,09	deleterious	3,43	23	0,4	0,55	neutral	0,42	disease	0,62	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,72	low_impact	-2,64	low_impact	-1,48	high_impact	2,6	0,38	0,9	1,75	6,64	N	0,32	N	0,69	disease_causing	0,51	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6474	6474	A	T	MI.3096	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	571	191	T	S	Aca/Tca	-4,27	0	0	probably_damaging	0,99	deleterious	0	neutral	2,51	neutral	-2,36	deleterious	-3,48	high_impact	4,49	neutral	0,67	damaging	0,09	deleterious	3,22	22,7	0,37	0,55	disease	0,58	disease	0,68	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-2,64	low_impact	-1,48	high_impact	3,05	0,54	0,9	1,75	6,64	N	0,4	N	0,79	polymorphism	0,74	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6474	6474	A	C	MI.3097	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	571	191	T	P	Aca/Cca	-4,27	0	0	probably_damaging	1	deleterious	0	neutral	2,45	deleterious	-4,81	deleterious	-5,23	high_impact	4,95	damaging	0,55	damaging	0,08	deleterious	3,43	23	0,13	0,55	neutral	0,37	disease	0,79	disease	0,78	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	3,47	0,43	0,9	1,75	6,64	P	0,61	P	0,92	disease_causing	0,84	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6475	6475	C	T	MI.3098	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	572	191	T	M	aCa/aTa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,49	neutral	-2,91	deleterious	-5,23	high_impact	4,74	neutral	0,69	damaging	0,07	deleterious	4,01	23,6	0,32	0,55	disease	0,84	disease	0,77	disease	0,68	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,28	0,63	0,9	1,75	6,64	P	0,65	P	0,96	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6475	6475	C	A	MI.3099	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	572	191	T	K	aCa/aAa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-4,02	deleterious	-5,23	high_impact	5,29	damaging	0,6	damaging	0,07	deleterious	4,44	24,2	0,13	0,55	disease	0,67	disease	0,84	disease	0,78	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,64	0,9	1,75	6,64	P	0,75	P	0,88	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8539	8539	C	A	MI.31	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	13	5	L	M	Ctg/Atg	-0,33	0	0	probably_damaging	0,99	neutral	0,05	neutral	4,17	neutral	-2,57	neutral	-1,38	medium_impact	1,96	neutral	0,79	neutral	0,59	deleterious	3,74	23,3	0,31	0,65	disease	0,57	neutral	0,21	neutral	0,31	neutral	0,46	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,69	low_impact	-2,65	medium_impact	-0,43	medium_impact	0,58	0,65	0,9	50,44	8,42	N	0,44	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8671	8671	C	A	MI.310	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	145	49	L	M	Cta/Ata	0,13	0,01	0	probably_damaging	1	neutral	0,2	neutral	4,11	neutral	-2,66	neutral	-0,97	low_impact	1,6	neutral	0,83	neutral	0,76	deleterious	2,5	19,45	0,22	0,65	disease	0,78	neutral	0,35	neutral	0,24	disease	0,66	3	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	-0,05	medium_impact	0,27	0,74	0,9	44,25	12,31	N	0,43	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6477	6477	G	C	MI.3100	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	574	192	A	P	Gca/Cca	-4,5	0	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-3,32	deleterious	-3,85	high_impact	4,84	damaging	0,58	damaging	0,05	deleterious	3,8	23,4	0,1	0,55	disease	0,69	disease	0,82	disease	0,65	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,65	0,9	2,14	6,81	P	0,62	P	0,85	polymorphism	0,7	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6477	6477	G	T	MI.3101	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	574	192	A	S	Gca/Tca	-4,5	0	0	possibly_damaging	0,84	neutral	0,22	neutral	2,73	neutral	-0,45	neutral	-2,25	low_impact	1,42	neutral	0,65	damaging	0,06	deleterious	3,26	22,8	0,35	0,55	neutral	0,2	disease	0,62	neutral	0,27	neutral	0,35	3	neutral	0,9	neutral	0,19	neutral	-3	deleterious	0,45	low_impact	-1,43	medium_impact	-0,11	medium_impact	0,21	0,63	0,9	2,14	6,81	N	0,28	N	0,64	polymorphism	0,95	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6477	6477	G	A	MI.3102	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	574	192	A	T	Gca/Aca	-4,5	0	0	possibly_damaging	0,67	neutral	0,1	neutral	2,54	neutral	-2,65	deleterious	-2,58	low_impact	1,46	damaging	0,59	damaging	0,14	deleterious	2,77	21,2	0,37	0,55	neutral	0,35	neutral	0,49	neutral	0,33	neutral	0,4	2	neutral	0,91	neutral	0,22	neutral	-3	deleterious	0,56	low_impact	-1,05	medium_impact	-0,34	medium_impact	0,25	0,55	0,9	2,14	6,81	N	0,33	N	0,2	polymorphism	0,89	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6478	6478	C	G	MI.3103	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	575	192	A	G	gCa/gGa	6,14	1	0	possibly_damaging	0,73	deleterious	0	neutral	2,53	neutral	-2,92	deleterious	-3,21	medium_impact	3,48	neutral	0,64	damaging	0,11	deleterious	1,89	15,5	0,26	0,55	disease	0,51	disease	0,64	disease	0,51	neutral	0,47	1	deleterious	1	neutral	0,14	deleterious	4	deleterious	0,49	low_impact	-1,16	low_impact	-1,48	high_impact	2,11	0,64	0,9	2,14	6,81	N	0,51	P	0,56	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6478	6478	C	A	MI.3104	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	575	192	A	E	gCa/gAa	6,14	1	0	probably_damaging	0,99	deleterious	0	neutral	2,52	deleterious	-3,52	deleterious	-3,84	high_impact	4,49	neutral	0,64	damaging	0,06	deleterious	4,43	24,2	0,12	0,55	disease	0,53	disease	0,84	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,64	low_impact	-1,48	high_impact	3,05	0,61	0,9	2,14	6,81	P	0,5	N	0,76	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6478	6478	C	T	MI.3105	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	575	192	A	V	gCa/gTa	6,14	1	0	benign	0,05	neutral	0,23	neutral	2,58	neutral	-1,84	deleterious	-2,62	medium_impact	2,29	neutral	0,64	damaging	0,09	deleterious	3,02	22,3	0,35	0,55	neutral	0,31	disease	0,61	neutral	0,36	neutral	0,36	3	neutral	0,75	deleterious	0,59	neutral	-3	neutral	0,21	medium_impact	0,45	medium_impact	-0,1	medium_impact	1,02	0,6	0,9	2,14	6,81	P	0,52	P	0,75	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6480	6480	G	A	MI.3106	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	577	193	V	I	Gtc/Atc	-9,36	0	0,01	benign	0	neutral	0,72	neutral	2,87	neutral	0,37	neutral	0,35	neutral_impact	-1,02	neutral	0,75	neutral	0,92	neutral	-1,1	0,01	0,52	0,6	neutral	0,18	neutral	0,08	neutral	0,19	neutral	0,26	5	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,42	low_impact	-2,04	0,76	0,9	11,7	20,86	N	0,42	N	0,04	disease_causing_automatic	0	0,01	rs199476128	Pathogenic	Cytochrome-c_oxidase_deficiency	RCV000010304.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	5,49	G6480A	Prostate Cancer/enriched in POAG cohort	+	-	Reported	4
chrM	6480	6480	G	T	MI.3107	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	577	193	V	F	Gtc/Ttc	-9,36	0	0,01	possibly_damaging	0,53	neutral	0,83	neutral	2,69	neutral	-1,02	neutral	-1,74	neutral_impact	0,2	neutral	0,65	neutral	0,63	deleterious	0,63	8,4	0,27	0,55	neutral	0,34	neutral	0,42	neutral	0,18	neutral	0,47	1	neutral	0,44	deleterious	0,65	neutral	-3	deleterious	0,54	medium_impact	-0,81	medium_impact	0,58	medium_impact	-0,91	0,58	0,9	11,7	20,86	N	0,35	N	0,87	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6480	6480	G	C	MI.3108	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	577	193	V	L	Gtc/Ctc	-9,36	0	0,01	benign	0,01	neutral	0,34	neutral	2,81	neutral	0,03	neutral	-0,4	neutral_impact	0,28	neutral	0,67	neutral	0,63	neutral	-0,21	1,07	0,39	0,55	neutral	0,32	neutral	0,32	neutral	0,22	neutral	0,47	1	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,15	medium_impact	1,12	medium_impact	0,03	medium_impact	-0,84	0,53	0,9	11,7	20,86	N	0,49	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6481	6481	T	G	MI.3109	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	578	193	V	G	gTc/gGc	2,44	0,99	0	possibly_damaging	0,73	deleterious	0	neutral	2,62	neutral	-2,34	deleterious	-5,09	low_impact	1,75	neutral	0,61	neutral	0,61	deleterious	1,87	15,39	0,23	0,55	disease	0,67	disease	0,57	neutral	0,38	neutral	0,48	0	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,68	low_impact	-1,16	low_impact	-1,48	medium_impact	0,52	0,49	0,9	11,7	20,86	N	0,46	N	0,75	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8671	8671	C	G	MI.311	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	145	49	L	V	Cta/Gta	0,13	0,01	0	probably_damaging	0,99	neutral	0,23	neutral	4,42	neutral	0,14	neutral	-1,89	low_impact	1,07	neutral	0,89	neutral	0,68	deleterious	2,22	17,67	0,28	0,65	disease	0,65	neutral	0,4	neutral	0,41	disease	0,62	2	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,76	low_impact	-2,65	medium_impact	-0,01	medium_impact	-0,18	0,68	0,9	44,25	12,31	N	0,43	N	0,69	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6481	6481	T	C	MI.3110	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	578	193	V	A	gTc/gCc	2,44	0,99	0	benign	0,26	deleterious	0	neutral	2,73	neutral	-0,55	deleterious	-2,72	medium_impact	2,22	neutral	0,64	neutral	0,54	neutral	1,61	13,93	0,36	0,55	neutral	0,38	neutral	0,41	neutral	0,36	neutral	0,47	1	deleterious	1	neutral	0,37	deleterious	1	neutral	0,35	medium_impact	-0,33	low_impact	-1,48	medium_impact	0,95	0,38	0,9	11,7	20,86	P	0,56	P	0,66	disease_causing	0,97	0,11	rs28721398	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6481	6481	T	A	MI.3111	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	578	193	V	D	gTc/gAc	2,44	0,99	0	possibly_damaging	0,74	deleterious	0	neutral	2,57	deleterious	-4,74	deleterious	-4,78	high_impact	3,54	damaging	0,58	neutral	0,42	deleterious	2,76	21,2	0,14	0,55	disease	0,8	disease	0,79	disease	0,58	disease	0,76	5	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,74	low_impact	-1,18	low_impact	-1,48	high_impact	2,17	0,52	0,9	11,7	20,86	P	0,46	N	0,9	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6483	6483	C	G	MI.3112	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	580	194	L	V	Cta/Gta	-10,28	0	0	probably_damaging	0,99	deleterious	0	neutral	2,46	neutral	-2,13	deleterious	-2,6	high_impact	4,93	damaging	0,47	damaging	0,06	deleterious	3,35	22,9	0,32	0,55	disease	0,52	disease	0,59	disease	0,61	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	high_impact	3,45	0,4	0,9	3,12	6,73	P	0,54	P	0,66	polymorphism	0,99	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6483	6483	C	A	MI.3113	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	580	194	L	M	Cta/Ata	-10,28	0	0	probably_damaging	1	deleterious	0,03	neutral	2,46	neutral	-2,19	neutral	-1,72	high_impact	3,56	damaging	0,44	damaging	0,11	deleterious	3,66	23,2	0,26	0,55	neutral	0,39	disease	0,52	neutral	0,38	neutral	0,33	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,72	low_impact	-3,58	medium_impact	-0,65	high_impact	2,19	0,4	0,9	3,12	6,73	N	0,37	N	0,59	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6484	6484	T	A	MI.3114	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	581	194	L	Q	cTa/cAa	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,36	deleterious	-4,91	deleterious	-5,2	high_impact	4,72	damaging	0,5	damaging	0,04	deleterious	4,02	23,6	0,14	0,55	disease	0,84	disease	0,79	disease	0,61	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,26	0,44	0,9	3,12	6,73	P	0,53	P	0,82	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6484	6484	T	C	MI.3115	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	581	194	L	P	cTa/cCa	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,36	deleterious	-5,3	deleterious	-6,08	high_impact	4,72	damaging	0,35	damaging	0,04	deleterious	3,84	23,4	0,18	0,55	disease	0,79	disease	0,79	disease	0,72	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,26	0,43	0,9	3,12	6,73	P	0,58	P	0,83	disease_causing	0,98	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6484	6484	T	G	MI.3116	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	581	194	L	R	cTa/cGa	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,36	deleterious	-4,74	deleterious	-5,21	high_impact	5,28	damaging	0,47	damaging	0,03	deleterious	4,15	23,8	0,16	0,55	disease	0,83	disease	0,86	disease	0,73	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,32	0,9	3,12	6,73	P	0,59	P	0,9	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6486	6486	C	G	MI.3117	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	583	195	L	V	Ctt/Gtt	-20	0	0	probably_damaging	0,99	deleterious	0,01	neutral	2,69	neutral	-0,94	deleterious	-2,61	medium_impact	3,29	damaging	0,35	neutral	0,32	deleterious	3,39	23	0,32	0,55	neutral	0,36	disease	0,56	disease	0,51	neutral	0,43	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,72	low_impact	-2,64	medium_impact	-0,92	medium_impact	1,94	0,39	0,9	6,63	7,85	P	0,52	P	0,66	polymorphism	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6486	6486	C	A	MI.3118	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	583	195	L	I	Ctt/Att	-20	0	0	probably_damaging	1	deleterious	0,01	neutral	2,79	neutral	-0,11	neutral	-1,74	medium_impact	3,03	damaging	0,45	neutral	0,46	deleterious	4,08	23,7	0,28	0,55	neutral	0,31	disease	0,62	neutral	0,46	neutral	0,4	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,73	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,7	0,52	0,9	6,63	7,85	N	0,47	N	0,54	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6486	6486	C	T	MI.3119	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	583	195	L	F	Ctt/Ttt	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-0,89	deleterious	-3,48	high_impact	5,22	damaging	0,42	neutral	0,32	deleterious	3,92	23,5	0,26	0,55	disease	0,62	disease	0,71	disease	0,58	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,72	0,36	0,9	6,63	7,85	P	0,6	P	0,87	polymorphism	0,96	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8672	8672	T	G	MI.312	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	146	49	L	R	cTa/cGa	-6,35	0	0	probably_damaging	1	deleterious	0,03	neutral	4,06	deleterious	-4,85	deleterious	-4,25	medium_impact	3,17	neutral	0,75	damaging	0,1	deleterious	4,05	23,7	0,08	0,65	disease	0,9	disease	0,85	disease	0,67	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,9	low_impact	-3,6	medium_impact	-0,56	medium_impact	1,62	0,54	0,9	44,25	12,31	N	0,25	N	0,99	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6487	6487	T	G	MI.3120	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	584	195	L	R	cTt/cGt	1,05	0,47	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-3,59	deleterious	-5,23	high_impact	5,22	damaging	0,49	damaging	0,26	deleterious	4,2	23,9	0,16	0,55	disease	0,74	disease	0,86	disease	0,71	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,72	0,39	0,9	6,63	7,85	P	0,64	P	0,9	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6487	6487	T	C	MI.3121	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	584	195	L	P	cTt/cCt	1,05	0,47	0	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-4,18	deleterious	-6,1	high_impact	4,87	damaging	0,39	neutral	0,29	deleterious	3,89	23,5	0,18	0,55	disease	0,81	disease	0,8	disease	0,71	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,4	0,48	0,9	6,63	7,85	P	0,72	P	0,83	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6487	6487	T	A	MI.3122	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	584	195	L	H	cTt/cAt	1,05	0,47	0	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-4,13	deleterious	-6,1	high_impact	5,22	damaging	0,5	damaging	0,27	deleterious	4,2	23,9	0,14	0,55	disease	0,8	disease	0,8	disease	0,67	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,72	0,34	0,9	6,63	7,85	P	0,59	P	0,83	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6489	6489	C	G	MI.3123	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	586	196	L	V	Ctc/Gtc	-15,6	0	0	probably_damaging	0,99	neutral	0,17	neutral	2,61	neutral	-1,15	neutral	-2,33	medium_impact	2,4	damaging	0,35	neutral	0,33	deleterious	3,4	23	0,39	0,55	neutral	0,3	neutral	0,5	neutral	0,25	neutral	0,41	2	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,71	low_impact	-2,64	medium_impact	-0,19	medium_impact	1,12	0,43	0,9	6,82	7,94	P	0,53	P	0,66	disease_causing_automatic	0,01	0,13	rs28461189	Pathogenic	Cytochrome_c_oxidase_i_deficiency	RCV000010308.2	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	6489	6489	C	A	MI.3124	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	586	196	L	I	Ctc/Atc	-15,6	0	0	probably_damaging	1	neutral	0,13	neutral	2,67	neutral	-1,31	neutral	-1,5	medium_impact	2,15	damaging	0,19	neutral	0,47	deleterious	4,04	23,7	0,29	0,55	neutral	0,37	disease	0,52	neutral	0,23	neutral	0,41	2	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,73	low_impact	-3,58	medium_impact	-0,27	medium_impact	0,89	0,57	0,9	6,82	7,94	P	0,81	P	0,54	disease_causing_automatic	0	0,04	rs28461189	Pathogenic	Cytochrome_c_oxidase_i_deficiency	RCV000010308.2	MedGen	.	.	CPD	0,15	C6489A	Therapy-Resistant Epilepsy	-	+	Reported	2
chrM	6489	6489	C	T	MI.3125	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	586	196	L	F	Ctc/Ttc	-15,6	0	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-3,18	deleterious	-3,35	high_impact	4,43	damaging	0,32	neutral	0,35	deleterious	3,96	23,6	0,32	0,55	disease	0,62	disease	0,72	neutral	0,48	disease	0,5	0	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,99	0,36	0,9	6,82	7,94	P	0,56	P	0,87	polymorphism	0,96	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6490	6490	T	A	MI.3126	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	587	196	L	H	cTc/cAc	-0,1	0	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-5,02	deleterious	-5,94	high_impact	5,12	damaging	0,41	neutral	0,31	deleterious	4,01	23,6	0,15	0,55	disease	0,79	disease	0,82	disease	0,58	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,63	0,35	0,9	6,82	7,94	P	0,65	P	0,83	disease_causing	0,99	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6490	6490	T	G	MI.3127	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	587	196	L	R	cTc/cGc	-0,1	0	0	probably_damaging	1	deleterious	0	neutral	2,43	deleterious	-4,48	deleterious	-5,13	high_impact	5,12	damaging	0,41	damaging	0,26	deleterious	4,09	23,7	0,14	0,55	neutral	0,36	disease	0,88	disease	0,63	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,63	0,38	0,9	6,82	7,94	P	0,63	P	0,9	disease_causing	0,99	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6490	6490	T	C	MI.3128	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	587	196	L	P	cTc/cCc	-0,1	0	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-5,06	deleterious	-5,92	high_impact	5,12	damaging	0,32	neutral	0,29	deleterious	3,83	23,4	0,15	0,55	disease	0,8	disease	0,83	disease	0,63	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,63	0,5	0,9	6,82	7,94	P	0,69	P	0,83	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6492	6492	C	G	MI.3129	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	589	197	L	V	Cta/Gta	-20	0	0	probably_damaging	0,97	neutral	0,09	neutral	2,78	neutral	-1,13	deleterious	-2,54	medium_impact	3,11	damaging	0,56	damaging	0,06	deleterious	3,37	22,9	0,5	0,55	neutral	0,26	disease	0,65	neutral	0,32	neutral	0,34	3	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,72	low_impact	-2,18	medium_impact	-0,37	medium_impact	1,77	0,52	0,9	3,31	7,25	N	0,31	N	0,66	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8672	8672	T	A	MI.313	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	146	49	L	Q	cTa/cAa	-6,35	0	0	probably_damaging	1	deleterious	0,03	neutral	4,06	deleterious	-4,97	deleterious	-4,21	medium_impact	2,82	neutral	0,8	damaging	0,16	deleterious	4,06	23,7	0,11	0,65	disease	0,91	disease	0,7	disease	0,54	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,85	low_impact	-3,6	medium_impact	-0,56	medium_impact	1,32	0,48	0,9	44,25	12,31	N	0,27	N	0,94	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6492	6492	C	A	MI.3130	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	589	197	L	M	Cta/Ata	-20	0	0	probably_damaging	1	deleterious	0,02	neutral	2,6	neutral	-2,81	neutral	-1,7	high_impact	3,57	damaging	0,57	damaging	0,09	deleterious	3,7	23,3	0,31	0,55	disease	0,63	disease	0,63	neutral	0,31	neutral	0,34	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-3,58	medium_impact	-0,75	high_impact	2,2	0,44	0,9	3,31	7,25	N	0,28	N	0,59	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6493	6493	T	C	MI.3131	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	590	197	L	P	cTa/cCa	0,36	0,06	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-4,78	deleterious	-5,99	high_impact	4,59	damaging	0,46	damaging	0,05	deleterious	3,89	23,5	0,17	0,55	disease	0,7	disease	0,85	disease	0,68	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,14	0,45	0,9	3,31	7,25	N	0,43	N	0,83	disease_causing	0,98	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6493	6493	T	G	MI.3132	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	590	197	L	R	cTa/cGa	0,36	0,06	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-4,21	deleterious	-5,13	high_impact	5,14	damaging	0,53	damaging	0,04	deleterious	4,17	23,8	0,17	0,55	disease	0,78	disease	0,9	disease	0,68	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,65	0,49	0,9	3,31	7,25	P	0,62	P	0,9	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6493	6493	T	A	MI.3133	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	590	197	L	Q	cTa/cAa	0,36	0,06	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-4,39	deleterious	-5,13	high_impact	5,14	damaging	0,55	damaging	0,05	deleterious	4,05	23,7	0,2	0,55	disease	0,79	disease	0,83	disease	0,54	disease	0,64	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,65	0,57	0,9	3,31	7,25	P	0,59	P	0,82	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6495	6495	T	G	MI.3134	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	592	198	S	A	Tct/Gct	-12,83	0	0	probably_damaging	0,99	neutral	0,09	neutral	2,95	neutral	-0,32	neutral	-2,37	low_impact	1,88	damaging	0,58	neutral	0,8	deleterious	2,56	19,86	0,44	0,55	neutral	0,16	neutral	0,42	neutral	0,32	neutral	0,39	2	deleterious	0,99	neutral	0,05	neutral	-2	deleterious	0,67	low_impact	-2,64	medium_impact	-0,37	medium_impact	0,64	0,61	0,9	9,55	8,54	N	0,43	N	0,35	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6495	6495	T	C	MI.3135	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	592	198	S	P	Tct/Cct	-12,83	0	0	probably_damaging	1	deleterious	0	neutral	2,75	deleterious	-3,33	deleterious	-4,23	high_impact	5,11	damaging	0,47	neutral	0,5	deleterious	3,92	23,5	0,24	0,55	disease	0,66	disease	0,86	disease	0,7	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,63	0,9	9,55	8,54	P	0,68	P	0,91	polymorphism	0,97	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6495	6495	T	A	MI.3136	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	592	198	S	T	Tct/Act	-12,83	0	0	probably_damaging	0,97	deleterious	0	neutral	2,84	neutral	-1,28	deleterious	-2,52	medium_impact	3,27	damaging	0,52	neutral	0,51	deleterious	3,78	23,4	0,33	0,55	neutral	0,28	disease	0,56	neutral	0,38	neutral	0,36	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,71	low_impact	-2,18	low_impact	-1,48	medium_impact	1,92	0,66	0,9	9,55	8,54	N	0,47	N	0,43	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6496	6496	C	A	MI.3137	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	593	198	S	Y	tCt/tAt	3,83	1	0	probably_damaging	1	deleterious	0	neutral	2,76	deleterious	-3,08	deleterious	-5,09	high_impact	5,11	damaging	0,48	neutral	0,41	deleterious	4,07	23,7	0,22	0,55	disease	0,57	disease	0,85	disease	0,6	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,6	0,9	9,55	8,54	P	0,69	P	0,92	disease_causing	1	0,34	.	.	.	.	.	.	COSM5656133	.	.	.	.	.	.	.	.
chrM	6496	6496	C	G	MI.3138	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	593	198	S	C	tCt/tGt	3,83	1	0	probably_damaging	1	deleterious	0	neutral	2,74	deleterious	-4,22	deleterious	-4,19	high_impact	4,3	damaging	0,49	neutral	0,44	deleterious	3,51	23,1	0,3	0,55	disease	0,68	disease	0,78	neutral	0,49	disease	0,61	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,87	0,57	0,9	9,55	8,54	P	0,5	N	0,85	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6496	6496	C	T	MI.3139	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	593	198	S	F	tCt/tTt	3,83	1	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-2,97	deleterious	-5,09	high_impact	4,42	damaging	0,43	neutral	0,43	deleterious	4,1	23,7	0,2	0,55	disease	0,5	disease	0,88	disease	0,6	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,98	0,35	0,9	9,55	8,54	P	0,69	P	0,98	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8672	8672	T	C	MI.314	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	146	49	L	P	cTa/cCa	-6,35	0	0	probably_damaging	1	neutral	0,09	neutral	4,05	deleterious	-5,31	deleterious	-5,13	low_impact	1,92	neutral	0,71	damaging	0,11	deleterious	3,81	23,4	0,1	0,65	disease	0,93	disease	0,87	disease	0,66	disease	0,83	7	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,28	medium_impact	0,55	0,52	0,9	44,25	12,31	N	0,21	N	0,85	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6498	6498	C	A	MI.3140	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	595	199	L	I	Ctc/Atc	-11,67	0	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-1,42	neutral	-1,57	medium_impact	3,28	damaging	0,25	neutral	0,47	deleterious	4,05	23,7	0,42	0,55	neutral	0,31	disease	0,66	neutral	0,33	neutral	0,47	1	deleterious	1	neutral	0	deleterious	5	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	medium_impact	1,93	0,76	0,9	2,53	6,72	P	0,85	P	0,54	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6498	6498	C	G	MI.3141	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	595	199	L	V	Ctc/Gtc	-11,67	0	0	probably_damaging	0,99	deleterious	0,04	neutral	2,68	neutral	-1,38	neutral	-2,43	medium_impact	3,47	damaging	0,29	neutral	0,35	deleterious	3,44	23	0,4	0,55	neutral	0,29	disease	0,61	neutral	0,49	neutral	0,44	1	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,73	low_impact	-2,64	medium_impact	-0,58	high_impact	2,11	0,62	0,9	2,53	6,72	P	0,78	P	0,66	polymorphism	0,98	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6498	6498	C	T	MI.3142	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	595	199	L	F	Ctc/Ttc	-11,67	0	0	probably_damaging	1	deleterious	0	neutral	2,77	neutral	-0,15	deleterious	-3,38	medium_impact	3	damaging	0,32	neutral	0,32	deleterious	3,96	23,6	0,4	0,55	neutral	0,27	disease	0,74	neutral	0,5	disease	0,52	0	deleterious	1	neutral	0	deleterious	5	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	medium_impact	1,67	0,6	0,9	2,53	6,72	P	0,56	P	0,87	polymorphism	0,89	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6499	6499	T	A	MI.3143	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	596	199	L	H	cTc/cAc	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-4,44	deleterious	-5,98	high_impact	5,17	damaging	0,43	neutral	0,29	deleterious	4,07	23,7	0,18	0,55	disease	0,76	disease	0,83	disease	0,67	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,54	0,9	2,53	6,72	P	0,66	P	0,83	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6499	6499	T	C	MI.3144	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	596	199	L	P	cTc/cCc	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-4,49	deleterious	-5,98	high_impact	5,17	damaging	0,36	neutral	0,45	deleterious	3,85	23,4	0,15	0,55	disease	0,76	disease	0,83	disease	0,71	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,58	0,9	2,53	6,72	P	0,73	P	0,83	disease_causing	0,87	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6499	6499	T	G	MI.3145	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	596	199	L	R	cTc/cGc	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-3,89	deleterious	-5,15	high_impact	5,17	damaging	0,42	damaging	0,27	deleterious	4,14	23,8	0,16	0,55	disease	0,69	disease	0,9	disease	0,72	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,58	0,9	2,53	6,72	P	0,69	P	0,9	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6501	6501	C	T	MI.3146	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	598	200	P	S	Cca/Tca	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,4	neutral	-2,91	deleterious	-6,92	high_impact	5,31	neutral	0,67	damaging	0,06	deleterious	3,85	23,4	0,4	0,55	disease	0,67	disease	0,8	disease	0,67	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,16	0,9	2,73	7,82	P	0,56	P	0,85	polymorphism	0,89	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6501	6501	C	A	MI.3147	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	598	200	P	T	Cca/Aca	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,38	deleterious	-3,11	deleterious	-6,92	high_impact	4,62	neutral	0,66	damaging	0,06	deleterious	3,65	23,2	0,3	0,55	disease	0,74	disease	0,72	disease	0,65	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,17	0,52	0,9	2,73	7,82	N	0,39	N	0,8	polymorphism	0,89	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6501	6501	C	G	MI.3148	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	598	200	P	A	Cca/Gca	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,46	neutral	-2,35	deleterious	-6,92	high_impact	5,31	neutral	0,68	damaging	0,07	deleterious	3,05	22,4	0,25	0,55	disease	0,63	disease	0,62	disease	0,68	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,62	0,9	2,73	7,82	P	0,56	P	0,76	polymorphism	0,93	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6502	6502	C	G	MI.3149	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	599	200	P	R	cCa/cGa	4,52	1	0	probably_damaging	1	deleterious	0	neutral	2,36	deleterious	-4,06	deleterious	-7,8	high_impact	4,96	neutral	0,63	damaging	0,05	deleterious	3,56	23,1	0,19	0,55	disease	0,89	disease	0,89	disease	0,8	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,49	0,9	2,73	7,82	P	0,65	P	0,9	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8674	8674	A	G	MI.315	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	148	50	I	V	Atc/Gtc	-2,88	0	0	benign	0,05	neutral	0,3	neutral	4,47	neutral	0,53	neutral	-0,33	low_impact	1,33	neutral	0,92	neutral	0,98	neutral	-0,3	0,67	0,64	0,7	neutral	0,34	neutral	0,18	neutral	0,26	neutral	0,29	4	neutral	0,68	deleterious	0,63	neutral	-6	neutral	0,14	medium_impact	0,46	medium_impact	0,08	medium_impact	0,04	0,5	0,9	17,7	19,1	N	0,44	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6502	6502	C	A	MI.3150	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	599	200	P	Q	cCa/cAa	4,52	1	0	probably_damaging	1	deleterious	0	neutral	2,36	deleterious	-4	deleterious	-6,93	high_impact	4,96	neutral	0,67	damaging	0,04	deleterious	4,08	23,7	0,2	0,55	disease	0,89	disease	0,85	disease	0,71	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,51	0,9	2,73	7,82	P	0,65	P	0,82	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6502	6502	C	T	MI.3151	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	599	200	P	L	cCa/cTa	4,52	1	0	probably_damaging	1	deleterious	0,02	neutral	2,51	neutral	-1,9	deleterious	-8,66	high_impact	4,62	neutral	0,68	damaging	0,03	deleterious	4,39	24,1	0,32	0,55	disease	0,86	disease	0,87	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,58	medium_impact	-0,75	high_impact	3,17	0,75	0,9	2,73	7,82	P	0,58	P	0,87	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6504	6504	G	C	MI.3152	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	601	201	V	L	Gtc/Ctc	-2,19	0	0	probably_damaging	0,99	deleterious	0	neutral	2,7	neutral	-1,7	deleterious	-2,54	high_impact	3,68	neutral	0,61	damaging	0,13	deleterious	3,62	23,2	0,4	0,55	disease	0,76	disease	0,76	disease	0,6	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	2,3	0,39	0,9	3,51	7,98	N	0,28	N	0,55	disease_causing	0,51	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6504	6504	G	A	MI.3153	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	601	201	V	I	Gtc/Atc	-2,19	0	0	probably_damaging	0,99	deleterious	0,02	neutral	2,71	neutral	-1,64	neutral	-0,82	medium_impact	2,9	damaging	0,56	damaging	0,18	deleterious	3,62	23,2	0,52	0,6	disease	0,78	disease	0,56	disease	0,52	disease	0,51	0	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,72	low_impact	-2,64	medium_impact	-0,75	medium_impact	1,58	0,68	0,9	3,51	7,98	N	0,33	N	0,24	polymorphism	0,77	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6504	6504	G	T	MI.3154	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	601	201	V	F	Gtc/Ttc	-2,19	0	0	probably_damaging	1	deleterious	0,02	neutral	2,62	deleterious	-3,39	deleterious	-4,25	high_impact	4,54	damaging	0,57	damaging	0,11	deleterious	3,86	23,5	0,17	0,55	disease	0,88	disease	0,87	disease	0,65	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,58	medium_impact	-0,75	high_impact	3,09	0,5	0,9	3,51	7,98	N	0,41	N	0,86	disease_causing	0,92	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6505	6505	T	A	MI.3155	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	602	201	V	D	gTc/gAc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-4,82	deleterious	-5,99	high_impact	4,33	neutral	0,67	damaging	0,12	deleterious	4,65	24,5	0,1	0,55	disease	0,89	disease	0,88	disease	0,74	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,9	0,49	0,9	3,51	7,98	P	0,56	P	0,83	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6505	6505	T	G	MI.3156	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	602	201	V	G	gTc/gGc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,74	neutral	-2,25	deleterious	-6	high_impact	4,68	neutral	0,61	damaging	0,17	deleterious	3,79	23,4	0,17	0,55	disease	0,64	disease	0,77	disease	0,63	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,22	0,48	0,9	3,51	7,98	P	0,59	P	0,71	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6505	6505	T	C	MI.3157	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	602	201	V	A	gTc/gCc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-1,33	deleterious	-3,42	high_impact	4,19	damaging	0,52	damaging	0,18	deleterious	3,6	23,2	0,37	0,55	disease	0,62	disease	0,58	disease	0,61	disease	0,64	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,77	0,28	0,9	3,51	7,98	P	0,6	P	0,47	disease_causing	1	0,17	rs28371932	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6507	6507	C	G	MI.3158	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	604	202	L	V	Cta/Gta	-12,83	0	0	probably_damaging	0,99	deleterious	0	neutral	2,54	neutral	-2,15	deleterious	-2,6	high_impact	4,22	damaging	0,43	damaging	0,15	deleterious	3,39	23	0,34	0,55	disease	0,55	disease	0,53	disease	0,51	disease	0,52	0	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	high_impact	2,8	0,61	0,9	3,51	7,17	N	0,43	N	0,66	polymorphism	0,99	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6507	6507	C	A	MI.3159	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	604	202	L	M	Cta/Ata	-12,83	0	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-4,69	neutral	-1,73	high_impact	4,17	neutral	0,6	damaging	0,17	deleterious	3,71	23,3	0,27	0,55	disease	0,77	disease	0,58	disease	0,51	disease	0,54	1	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,75	0,63	0,9	3,51	7,17	N	0,35	N	0,59	polymorphism	0,99	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8674	8674	A	C	MI.316	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	148	50	I	L	Atc/Ctc	-2,88	0	0	benign	0,05	neutral	1	neutral	4,43	neutral	0,29	neutral	-1,26	low_impact	1	neutral	0,9	neutral	0,95	deleterious	0,35	6,16	0,44	0,65	neutral	0,41	neutral	0,22	neutral	0,19	neutral	0,43	2	neutral	0,05	deleterious	0,98	neutral	-6	neutral	0,17	medium_impact	0,46	high_impact	1,98	medium_impact	-0,24	0,73	0,9	17,7	19,1	N	0,38	N	0,34	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6508	6508	T	C	MI.3160	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	605	202	L	P	cTa/cCa	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-6,79	deleterious	-6,07	high_impact	4,22	damaging	0,45	damaging	0,13	deleterious	3,9	23,5	0,17	0,55	disease	0,96	disease	0,76	disease	0,7	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,8	0,48	0,9	3,51	7,17	N	0,32	N	0,83	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6508	6508	T	A	MI.3161	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	605	202	L	Q	cTa/cAa	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	2,41	deleterious	-6,38	deleterious	-5,2	high_impact	5,26	damaging	0,53	damaging	0,12	deleterious	4,06	23,7	0,16	0,55	disease	0,95	disease	0,77	disease	0,62	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,58	0,9	3,51	7,17	P	0,55	P	0,82	polymorphism	0,95	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6508	6508	T	G	MI.3162	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	605	202	L	R	cTa/cGa	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-6,26	deleterious	-5,2	high_impact	5,26	damaging	0,54	damaging	0,11	deleterious	4,16	23,8	0,16	0,55	disease	0,96	disease	0,85	disease	0,74	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,41	0,9	3,51	7,17	P	0,58	P	0,9	polymorphism	0,94	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6510	6510	G	C	MI.3163	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	607	203	A	P	Gct/Cct	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-4,47	deleterious	-4,34	high_impact	5,25	damaging	0,51	damaging	0,08	deleterious	3,78	23,4	0,15	0,55	disease	0,74	disease	0,81	disease	0,71	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,75	0,61	0,9	4,68	6,73	P	0,62	P	0,85	disease_causing	0,98	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6510	6510	G	A	MI.3164	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	607	203	A	T	Gct/Act	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-1,79	deleterious	-3,46	medium_impact	3,36	neutral	0,62	damaging	0,08	deleterious	4,19	23,8	0,27	0,55	neutral	0,25	disease	0,65	neutral	0,49	neutral	0,5	0	deleterious	1	neutral	0	deleterious	5	deleterious	0,72	low_impact	-3,58	low_impact	-1,48	high_impact	2	0,68	0,9	4,68	6,73	N	0,32	N	0,2	disease_causing	0,93	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6510	6510	G	T	MI.3165	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	607	203	A	S	Gct/Tct	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-3,49	deleterious	-2,59	high_impact	3,65	neutral	0,64	damaging	0,08	deleterious	3,67	23,3	0,31	0,55	neutral	0,41	disease	0,69	neutral	0,48	neutral	0,46	1	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	2,27	0,57	0,9	4,68	6,73	N	0,31	N	0,64	disease_causing	0,86	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6511	6511	C	G	MI.3166	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	608	203	A	G	gCt/gGt	9,15	1	0	probably_damaging	0,99	deleterious	0	neutral	2,57	deleterious	-3,35	deleterious	-3,47	high_impact	3,68	neutral	0,64	damaging	0,07	deleterious	3,9	23,5	0,24	0,55	neutral	0,43	disease	0,64	neutral	0,49	neutral	0,44	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,64	low_impact	-1,48	high_impact	2,3	0,71	0,9	4,68	6,73	N	0,48	N	0,56	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6511	6511	C	A	MI.3167	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	608	203	A	D	gCt/gAt	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-4,82	deleterious	-5,2	high_impact	5,25	damaging	0,55	damaging	0,05	deleterious	4,47	24,2	0,13	0,55	disease	0,67	disease	0,87	disease	0,7	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,75	0,49	0,9	4,68	6,73	P	0,69	P	0,89	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6511	6511	C	T	MI.3168	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	608	203	A	V	gCt/gTt	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,65	neutral	-2,05	deleterious	-3,47	high_impact	5,25	neutral	0,61	damaging	0,06	deleterious	4,29	24	0,36	0,55	neutral	0,45	disease	0,73	disease	0,59	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	3,75	0,59	0,9	4,68	6,73	P	0,72	P	0,75	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6513	6513	G	T	MI.3169	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	610	204	A	S	Gct/Tct	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-1,69	neutral	-0,22	neutral_impact	0,51	damaging	0,51	damaging	0,08	deleterious	3,71	23,3	0,39	0,55	disease	0,58	disease	0,58	neutral	0,41	neutral	0,5	0	deleterious	1	neutral	0	deleterious	2	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	medium_impact	-0,63	0,61	0,9	1,95	6,7	N	0,34	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8674	8674	A	T	MI.317	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	148	50	I	F	Atc/Ttc	-2,88	0	0	possibly_damaging	0,47	neutral	0,33	neutral	4,32	neutral	-0,81	deleterious	-3,07	neutral_impact	0,78	neutral	0,88	neutral	0,77	neutral	0,94	10,29	0,52	0,65	disease	0,71	neutral	0,43	neutral	0,26	disease	0,64	3	neutral	0,64	neutral	0,43	neutral	-3	deleterious	0,53	medium_impact	-0,71	medium_impact	0,12	medium_impact	-0,43	0,7	0,9	17,7	19,1	N	0,37	N	0,66	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6513	6513	G	A	MI.3170	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	610	204	A	T	Gct/Act	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-1,22	neutral	-1,87	low_impact	1,71	damaging	0,49	damaging	0,07	deleterious	4,21	23,9	0,4	0,55	disease	0,56	neutral	0,43	disease	0,51	disease	0,62	2	deleterious	1	neutral	0	deleterious	2	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	medium_impact	0,48	0,55	0,9	1,95	6,7	N	0,35	N	0,2	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6513	6513	G	C	MI.3171	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	610	204	A	P	Gct/Cct	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-3,74	neutral	-1,97	medium_impact	2,4	damaging	0,49	damaging	0,06	deleterious	3,86	23,5	0,19	0,55	disease	0,79	disease	0,88	disease	0,64	disease	0,81	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	medium_impact	1,12	0,62	0,9	1,95	6,7	N	0,26	N	0,85	polymorphism	0,97	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6514	6514	C	G	MI.3172	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	611	204	A	G	gCt/gGt	5,22	1	0	probably_damaging	0,99	neutral	1	neutral	2,7	neutral	-1,06	neutral	4,43	neutral_impact	-2,79	damaging	0,54	damaging	0,13	neutral	1,27	12,09	0,25	0,55	neutral	0,28	neutral	0,08	neutral	0,19	neutral	0,29	4	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,65	low_impact	-2,64	high_impact	1,86	low_impact	-3,68	0,58	0,9	1,95	6,7	N	0,47	N	0,56	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6514	6514	C	A	MI.3173	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	611	204	A	D	gCt/gAt	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-4,03	neutral	-1,24	medium_impact	2,06	damaging	0,51	damaging	0,05	deleterious	4,46	24,2	0,17	0,55	disease	0,82	disease	0,86	disease	0,64	disease	0,8	6	deleterious	1	deleterious	0	deleterious	5	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	medium_impact	0,8	0,51	0,9	1,95	6,7	N	0,44	N	0,89	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6514	6514	C	T	MI.3174	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	611	204	A	V	gCt/gTt	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,87	neutral	0,42	deleterious	-2,67	low_impact	1,43	damaging	0,5	damaging	0,06	deleterious	4,47	24,2	0,34	0,55	neutral	0,18	disease	0,66	disease	0,53	disease	0,61	2	deleterious	1	deleterious	0	deleterious	2	deleterious	0,71	low_impact	-3,58	low_impact	-1,48	medium_impact	0,22	0,46	0,9	1,95	6,7	P	0,48	N	0,75	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6516	6516	G	C	MI.3175	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	613	205	G	R	Ggc/Cgc	-7,51	0	0	probably_damaging	1	deleterious	0	neutral	2,88	neutral	-1,76	neutral	-1,49	medium_impact	2,46	damaging	0,47	damaging	0,01	deleterious	4	23,6	0,17	0,55	disease	0,57	disease	0,9	disease	0,63	disease	0,78	6	deleterious	1	deleterious	0	deleterious	5	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	medium_impact	1,17	0,8	0,9	2,14	8,1	N	0,27	N	0,95	polymorphism	0,97	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6516	6516	G	T	MI.3176	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	613	205	G	C	Ggc/Tgc	-7,51	0	0	probably_damaging	1	deleterious	0	neutral	2,86	deleterious	-4,44	neutral	-0,81	medium_impact	2,62	damaging	0,51	damaging	0,01	deleterious	4,18	23,8	0,11	0,55	disease	0,82	disease	0,84	neutral	0,43	disease	0,76	5	deleterious	1	deleterious	0	deleterious	5	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	medium_impact	1,32	0,66	0,9	2,14	8,1	N	0,28	N	0,98	polymorphism	0,95	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6516	6516	G	A	MI.3177	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	613	205	G	S	Ggc/Agc	-7,51	0	0	benign	0,42	neutral	0,07	neutral	2,91	neutral	-0,73	neutral	0,25	medium_impact	1,97	damaging	0,46	damaging	0,02	deleterious	4,21	23,9	0,32	0,55	neutral	0,22	disease	0,68	neutral	0,41	disease	0,5	0	neutral	0,92	neutral	0,33	neutral	-3	neutral	0,27	medium_impact	-0,62	medium_impact	-0,43	medium_impact	0,72	0,69	0,9	2,14	8,1	N	0,37	N	0,73	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6517	6517	G	A	MI.3178	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	614	205	G	D	gGc/gAc	9,15	1	0	probably_damaging	0,99	deleterious	0	neutral	2,87	neutral	-1,78	neutral	-2,17	medium_impact	3,16	damaging	0,47	damaging	0,01	deleterious	3,84	23,4	0,13	0,55	disease	0,55	disease	0,87	disease	0,66	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	medium_impact	1,82	0,42	0,9	2,14	8,1	P	0,52	P	0,97	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6517	6517	G	C	MI.3179	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	614	205	G	A	gGc/gCc	9,15	1	0	possibly_damaging	0,6	neutral	1	neutral	3,21	neutral	1,15	neutral	2,58	neutral_impact	-1,99	damaging	0,51	damaging	0,17	deleterious	0,39	6,53	0,31	0,55	neutral	0,18	neutral	0,12	neutral	0,13	neutral	0,27	5	neutral	0,6	deleterious	0,7	neutral	-3	deleterious	0,52	medium_impact	-0,92	high_impact	1,86	low_impact	-2,94	0,57	0,9	2,14	8,1	P	0,53	P	0,64	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8675	8675	T	G	MI.318	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	149	50	I	S	aTc/aGc	-0,57	0	0	benign	0,11	neutral	0,14	neutral	4,26	neutral	-1,89	deleterious	-4,39	medium_impact	1,94	neutral	0,83	neutral	0,65	deleterious	2,26	17,9	0,29	0,65	disease	0,65	disease	0,6	neutral	0,32	disease	0,5	0	neutral	0,84	deleterious	0,52	neutral	-3	neutral	0,31	medium_impact	0,11	medium_impact	-0,15	medium_impact	0,57	0,5	0,9	17,7	19,1	N	0,38	N	0,65	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6517	6517	G	T	MI.3180	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	614	205	G	V	gGc/gTc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,96	neutral	-1,72	neutral	-0,8	medium_impact	2,19	damaging	0,48	damaging	0,01	deleterious	3,8	23,4	0,16	0,55	disease	0,61	disease	0,79	disease	0,56	disease	0,72	4	deleterious	1	deleterious	0	deleterious	5	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	medium_impact	0,92	0,51	0,9	2,14	8,1	N	0,47	N	0,93	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6519	6519	A	G	MI.3181	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	616	206	I	V	Atc/Gtc	-14,22	0	0	probably_damaging	0,95	deleterious	0,01	neutral	2,91	neutral	0,01	neutral	-0,86	high_impact	3,65	damaging	0,58	damaging	0,17	deleterious	3,11	22,5	0,64	0,7	neutral	0,22	neutral	0,46	neutral	0,48	neutral	0,4	2	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,6	low_impact	-1,96	medium_impact	-0,92	high_impact	2,27	0,63	0,9	3,31	6,64	N	0,4	N	0,23	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6519	6519	A	T	MI.3182	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	616	206	I	F	Atc/Ttc	-14,22	0	0	probably_damaging	1	deleterious	0,04	neutral	2,84	neutral	-1,66	deleterious	-3,42	high_impact	4,34	damaging	0,56	damaging	0,08	deleterious	3,84	23,4	0,34	0,55	disease	0,56	disease	0,79	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,78	low_impact	-3,58	medium_impact	-0,58	high_impact	2,91	0,84	0,9	3,31	6,64	N	0,32	N	0,85	polymorphism	0,71	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6519	6519	A	C	MI.3183	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	616	206	I	L	Atc/Ctc	-14,22	0	0	probably_damaging	0,98	neutral	0,1	neutral	3,03	neutral	0,55	neutral	-1,65	medium_impact	2,62	neutral	0,61	damaging	0,1	deleterious	3,83	23,4	0,49	0,55	neutral	0,18	disease	0,62	neutral	0,26	neutral	0,4	2	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,47	low_impact	-2,35	medium_impact	-0,34	medium_impact	1,32	0,82	0,9	3,31	6,64	N	0,34	N	0,61	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6520	6520	T	A	MI.3184	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	617	206	I	N	aTc/aAc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,77	deleterious	-3,37	deleterious	-6,02	high_impact	4,8	damaging	0,56	damaging	0,09	deleterious	4,48	24,2	0,23	0,55	disease	0,69	disease	0,85	disease	0,63	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,33	0,77	0,9	3,31	6,64	P	0,66	P	0,94	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6520	6520	T	G	MI.3185	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	617	206	I	S	aTc/aGc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,8	neutral	-2	deleterious	-5,15	high_impact	5,14	damaging	0,6	damaging	0,2	deleterious	4,34	24	0,27	0,55	disease	0,54	disease	0,86	disease	0,63	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,65	0,7	0,9	3,31	6,64	P	0,7	P	0,62	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6520	6520	T	C	MI.3186	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	617	206	I	T	aTc/aCc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,82	neutral	-1,66	deleterious	-4,28	high_impact	4,8	damaging	0,6	damaging	0,09	deleterious	3,47	23	0,46	0,55	neutral	0,49	disease	0,73	disease	0,61	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	3,33	0,65	0,9	3,31	6,64	P	0,67	P	0,76	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6521	6521	C	A	MI.3187	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	618	206	I	M	atC/atA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,8	neutral	-1,98	deleterious	-2,54	high_impact	4,25	neutral	0,63	damaging	0,08	deleterious	3,79	23,4	0,43	0,55	disease	0,56	disease	0,72	neutral	0,47	disease	0,51	0	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	high_impact	2,83	0,84	0,9	3,31	6,64	N	0,44	N	0,76	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6521	6521	C	G	MI.3188	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	618	206	I	M	atC/atG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,8	neutral	-1,98	deleterious	-2,54	high_impact	4,25	neutral	0,63	damaging	0,08	deleterious	3,35	22,9	0,43	0,55	disease	0,56	disease	0,72	neutral	0,47	disease	0,51	0	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	high_impact	2,83	0,84	0,9	3,31	6,64	N	0,44	N	0,76	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6522	6522	A	C	MI.3189	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	619	207	T	P	Act/Cct	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-3,75	deleterious	-5,19	high_impact	5,22	damaging	0,55	damaging	0,13	deleterious	3,49	23,1	0,2	0,55	disease	0,7	disease	0,85	disease	0,77	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,72	0,58	0,9	2,14	6,69	P	0,68	P	0,92	disease_causing	0,93	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8675	8675	T	A	MI.319	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	149	50	I	N	aTc/aAc	-0,57	0	0	benign	0,25	neutral	0,1	neutral	4,26	neutral	-1,86	deleterious	-5,06	medium_impact	2	neutral	0,81	neutral	0,42	deleterious	2,66	20,5	0,34	0,65	disease	0,84	disease	0,69	neutral	0,42	disease	0,58	2	neutral	0,88	neutral	0,43	neutral	-3	deleterious	0,55	medium_impact	-0,3	medium_impact	-0,25	medium_impact	0,62	0,41	0,9	17,7	19,1	N	0,31	N	0,76	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6522	6522	A	T	MI.3190	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	619	207	T	S	Act/Tct	-2,42	0	0	probably_damaging	0,98	deleterious	0	neutral	2,65	neutral	-2,13	deleterious	-3,45	high_impact	4,67	neutral	0,7	damaging	0,14	deleterious	3,33	22,9	0,49	0,55	neutral	0,48	disease	0,76	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-2,35	low_impact	-1,48	high_impact	3,21	0,66	0,9	2,14	6,69	N	0,53	P	0,79	polymorphism	0,54	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6522	6522	A	G	MI.3191	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	619	207	T	A	Act/Gct	-2,42	0	0	probably_damaging	0,98	deleterious	0	neutral	2,73	neutral	-0,5	deleterious	-4,32	high_impact	4,53	neutral	0,75	damaging	0,13	deleterious	3,52	23,1	0,59	0,65	neutral	0,27	disease	0,68	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,69	low_impact	-2,35	low_impact	-1,48	high_impact	3,08	0,44	0,9	2,14	6,69	N	0,45	N	0,69	disease_causing	0,71	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6523	6523	C	G	MI.3192	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	620	207	T	S	aCt/aGt	8,69	1	0	probably_damaging	0,98	deleterious	0	neutral	2,65	neutral	-2,13	deleterious	-3,45	high_impact	4,67	neutral	0,7	damaging	0,14	deleterious	3,52	23,1	0,49	0,55	neutral	0,48	disease	0,76	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-2,35	low_impact	-1,48	high_impact	3,21	0,66	0,9	2,14	6,69	P	0,59	P	0,79	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6523	6523	C	A	MI.3193	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	620	207	T	N	aCt/aAt	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-3,32	deleterious	-4,33	high_impact	5,22	damaging	0,57	damaging	0,09	deleterious	3,61	23,2	0,47	0,55	disease	0,66	disease	0,83	disease	0,67	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,72	0,73	0,9	2,14	6,69	P	0,7	P	0,8	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6523	6523	C	T	MI.3194	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	620	207	T	I	aCt/aTt	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,79	neutral	-0,47	deleterious	-5,18	high_impact	3,75	damaging	0,57	damaging	0,13	deleterious	3,9	23,5	0,32	0,55	neutral	0,26	disease	0,87	disease	0,56	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	high_impact	2,36	0,61	0,9	2,14	6,69	N	0,44	N	0,92	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6525	6525	A	T	MI.3195	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	622	208	M	L	Ata/Tta	-10,51	0	0	possibly_damaging	0,9	deleterious	0	neutral	2,86	neutral	-0,85	deleterious	-2,58	high_impact	3,61	neutral	0,69	damaging	0,1	deleterious	3,58	23,2	0,41	0,55	neutral	0,2	disease	0,8	disease	0,57	disease	0,58	2	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,6	low_impact	-1,65	low_impact	-1,48	high_impact	2,23	0,63	0,9	4,29	6,71	N	0,32	N	0,61	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6525	6525	A	G	MI.3196	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	622	208	M	V	Ata/Gta	-10,51	0	0	probably_damaging	0,94	deleterious	0	neutral	2,75	neutral	-1,97	deleterious	-3,44	high_impact	4,26	neutral	0,65	damaging	0,12	deleterious	2,88	21,8	0,42	0,55	disease	0,54	disease	0,79	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,76	low_impact	-1,88	low_impact	-1,48	high_impact	2,83	0,58	0,9	4,29	6,71	N	0,35	N	0,88	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6525	6525	A	C	MI.3197	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	622	208	M	L	Ata/Cta	-10,51	0	0	possibly_damaging	0,9	deleterious	0	neutral	2,86	neutral	-0,85	deleterious	-2,58	high_impact	3,61	neutral	0,69	damaging	0,1	deleterious	3,39	23	0,41	0,55	neutral	0,2	disease	0,8	disease	0,57	disease	0,58	2	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,6	low_impact	-1,65	low_impact	-1,48	high_impact	2,23	0,63	0,9	4,29	6,71	N	0,31	N	0,61	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6526	6526	T	C	MI.3198	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	623	208	M	T	aTa/aCa	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-2,62	deleterious	-5,15	high_impact	5,24	damaging	0,6	damaging	0,17	deleterious	2,97	22,1	0,28	0,55	disease	0,77	disease	0,85	disease	0,65	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,35	0,9	4,29	6,71	P	0,69	P	0,79	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6526	6526	T	A	MI.3199	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	623	208	M	K	aTa/aAa	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,69	deleterious	-3,37	deleterious	-5,16	high_impact	5,24	neutral	0,65	damaging	0,1	deleterious	3,95	23,6	0,12	0,55	disease	0,89	disease	0,91	disease	0,78	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,46	0,9	4,29	6,71	P	0,76	P	0,93	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8540	8540	T	C	MI.32	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	14	5	L	P	cTg/cCg	-1,95	0	0	probably_damaging	0,99	deleterious	0	neutral	4,1	deleterious	-4,67	deleterious	-5,58	medium_impact	2,93	neutral	0,72	neutral	0,32	deleterious	3,72	23,3	0,23	0,65	disease	0,89	disease	0,73	disease	0,78	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,88	low_impact	-2,65	low_impact	-1,4	medium_impact	1,41	0,55	0,9	50,44	8,42	N	0,28	N	1	disease_causing	1	0,35	rs878852987	Uncertain significance	not_provided	RCV000224948.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	8675	8675	T	C	MI.320	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	149	50	I	T	aTc/aCc	-0,57	0	0	benign	0,01	neutral	0,18	neutral	4,35	neutral	-0,44	deleterious	-3,14	low_impact	1,33	neutral	0,88	neutral	0,96	deleterious	0,15	4,1	0,44	0,65	disease	0,56	neutral	0,37	neutral	0,28	disease	0,61	2	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,17	medium_impact	1,14	medium_impact	-0,08	medium_impact	0,04	0,48	0,9	17,7	19,1	N	0,4	N	0,18	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6527	6527	A	C	MI.3200	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	624	208	M	I	atA/atC	7,53	1	0	probably_damaging	0,96	deleterious	0	neutral	2,72	neutral	-2,45	deleterious	-3,44	high_impact	4,34	damaging	0,59	damaging	0,13	deleterious	3,45	23	0,38	0,55	neutral	0,48	disease	0,81	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,77	low_impact	-2,06	low_impact	-1,48	high_impact	2,91	0,71	0,9	4,29	6,71	P	0,57	P	0,87	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6527	6527	A	T	MI.3201	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	624	208	M	I	atA/atT	7,53	1	0	probably_damaging	0,96	deleterious	0	neutral	2,72	neutral	-2,45	deleterious	-3,44	high_impact	4,34	damaging	0,59	damaging	0,13	deleterious	3,5	23,1	0,38	0,55	neutral	0,48	disease	0,81	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,77	low_impact	-2,06	low_impact	-1,48	high_impact	2,91	0,71	0,9	4,29	6,71	P	0,54	P	0,87	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6528	6528	C	G	MI.3202	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	625	209	L	V	Cta/Gta	-1,03	0	0	probably_damaging	0,99	deleterious	0	neutral	2,47	neutral	-2,16	deleterious	-2,6	high_impact	3,8	damaging	0,51	damaging	0,04	deleterious	3,43	23	0,34	0,55	disease	0,54	disease	0,63	neutral	0,39	neutral	0,46	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	2,41	0,75	0,9	2,34	7,33	N	0,32	N	0,66	disease_causing	0,56	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6528	6528	C	A	MI.3203	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	625	209	L	M	Cta/Ata	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	2,36	deleterious	-3,12	neutral	-1,73	high_impact	4,38	damaging	0,56	damaging	0,07	deleterious	3,74	23,3	0,26	0,55	neutral	0,26	disease	0,69	neutral	0,35	neutral	0,5	0	deleterious	1	neutral	0	deleterious	6	deleterious	0,72	low_impact	-3,58	low_impact	-1,48	high_impact	2,95	0,7	0,9	2,34	7,33	N	0,35	N	0,59	disease_causing	0,51	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6529	6529	T	A	MI.3204	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	626	209	L	Q	cTa/cAa	1,05	0,4	0	probably_damaging	1	deleterious	0	neutral	2,33	deleterious	-3,91	deleterious	-5,2	high_impact	5,27	damaging	0,55	damaging	0,03	deleterious	4,24	23,9	0,15	0,55	disease	0,56	disease	0,87	disease	0,54	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,77	0,62	0,9	2,34	7,33	P	0,57	P	0,82	disease_causing	0,88	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6529	6529	T	G	MI.3205	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	626	209	L	R	cTa/cGa	1,05	0,4	0	probably_damaging	1	deleterious	0	neutral	2,34	deleterious	-4,81	deleterious	-5,2	high_impact	5,27	damaging	0,52	damaging	0,03	deleterious	4,17	23,8	0,14	0,55	disease	0,79	disease	0,9	disease	0,68	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,77	0,52	0,9	2,34	7,33	P	0,61	P	0,9	disease_causing	0,9	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6529	6529	T	C	MI.3206	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	626	209	L	P	cTa/cCa	1,05	0,4	0	probably_damaging	1	deleterious	0	neutral	2,33	deleterious	-5,43	deleterious	-6,07	high_impact	5,27	damaging	0,41	damaging	0,03	deleterious	3,96	23,6	0,16	0,55	disease	0,87	disease	0,84	disease	0,69	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,77	0,59	0,9	2,34	7,33	P	0,6	P	0,83	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6531	6531	C	G	MI.3207	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	628	210	L	V	Cta/Gta	-2,88	0	0	probably_damaging	0,99	deleterious	0	neutral	2,6	neutral	-1,71	deleterious	-2,59	high_impact	4,67	damaging	0,48	damaging	0,04	deleterious	3,43	23	0,41	0,55	neutral	0,39	disease	0,7	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	high_impact	3,21	0,62	0,9	2,92	6,75	N	0,46	N	0,66	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6531	6531	C	A	MI.3208	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	628	210	L	M	Cta/Ata	-2,88	0	0	probably_damaging	1	deleterious	0	neutral	2,56	neutral	-2,89	neutral	-1,73	high_impact	4,88	damaging	0,52	damaging	0,06	deleterious	3,76	23,3	0,32	0,55	disease	0,52	disease	0,73	disease	0,56	disease	0,64	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	3,41	0,65	0,9	2,92	6,75	P	0,58	P	0,59	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6532	6532	T	G	MI.3209	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	629	210	L	R	cTa/cGa	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-4,44	deleterious	-5,19	high_impact	5,22	damaging	0,48	damaging	0,03	deleterious	4,17	23,8	0,17	0,55	disease	0,72	disease	0,92	disease	0,71	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,72	0,67	0,9	2,92	6,75	P	0,58	P	0,9	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8676	8676	C	A	MI.321	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	150	50	I	M	atC/atA	1,98	0,02	0	possibly_damaging	0,66	neutral	0,16	neutral	4,28	neutral	-1,48	neutral	-1,92	low_impact	1,16	neutral	0,88	neutral	0,68	deleterious	2,26	17,89	0,56	0,65	disease	0,71	neutral	0,31	neutral	0,2	disease	0,63	3	neutral	0,86	neutral	0,25	neutral	-3	deleterious	0,59	low_impact	-1,03	medium_impact	-0,12	medium_impact	-0,1	0,75	0,9	17,7	19,1	N	0,45	N	0,6	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6532	6532	T	A	MI.3210	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	629	210	L	Q	cTa/cAa	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-4,59	deleterious	-5,19	high_impact	5,22	damaging	0,51	damaging	0,04	deleterious	4,18	23,8	0,19	0,55	disease	0,74	disease	0,89	disease	0,58	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,72	0,68	0,9	2,92	6,75	P	0,59	P	0,82	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6532	6532	T	C	MI.3211	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	629	210	L	P	cTa/cCa	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-5,04	deleterious	-6,06	high_impact	5,22	damaging	0,34	damaging	0,05	deleterious	3,95	23,6	0,16	0,55	disease	0,79	disease	0,87	disease	0,71	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,72	0,56	0,9	2,92	6,75	P	0,57	P	0,83	disease_causing	0,86	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6534	6534	A	T	MI.3212	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	631	211	T	S	Aca/Tca	-5,19	0	0	probably_damaging	0,99	deleterious	0	neutral	2,78	neutral	-1,6	deleterious	-3,33	medium_impact	3,18	neutral	0,62	damaging	0,15	deleterious	3,27	22,8	0,43	0,55	neutral	0,3	disease	0,75	neutral	0,28	neutral	0,37	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,72	low_impact	-2,64	low_impact	-1,48	medium_impact	1,84	0,72	0,9	2,14	7,99	N	0,35	N	0,79	polymorphism	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6534	6534	A	G	MI.3213	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	631	211	T	A	Aca/Gca	-5,19	0	0	probably_damaging	0,99	deleterious	0,01	neutral	2,82	neutral	-0,53	deleterious	-4,19	medium_impact	2,58	neutral	0,78	damaging	0,12	deleterious	3,5	23,1	0,47	0,55	neutral	0,23	disease	0,7	neutral	0,46	neutral	0,45	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,69	low_impact	-2,64	medium_impact	-0,92	medium_impact	1,28	0,54	0,9	2,14	7,99	N	0,27	N	0,69	polymorphism	0,95	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6534	6534	A	C	MI.3214	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	631	211	T	P	Aca/Cca	-5,19	0	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,61	deleterious	-5,09	high_impact	4,92	damaging	0,58	damaging	0,11	deleterious	3,51	23,1	0,19	0,55	disease	0,66	disease	0,89	disease	0,71	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,61	0,9	2,14	7,99	P	0,65	P	0,92	polymorphism	0,8	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6535	6535	C	T	MI.3215	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	632	211	T	M	aCa/aTa	6,84	1	0	probably_damaging	1	neutral	0,11	neutral	2,77	neutral	-0,87	deleterious	-5,01	medium_impact	3,15	neutral	0,73	damaging	0,11	deleterious	4,01	23,6	0,27	0,55	neutral	0,5	disease	0,85	neutral	0,28	neutral	0,39	2	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,73	low_impact	-3,58	medium_impact	-0,31	medium_impact	1,81	0,7	0,9	2,14	7,99	N	0,48	N	0,96	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6535	6535	C	A	MI.3216	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	632	211	T	K	aCa/aAa	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,73	neutral	-2,77	deleterious	-5,06	high_impact	4,92	neutral	0,62	damaging	0,09	deleterious	4,51	24,3	0,21	0,55	neutral	0,5	disease	0,93	disease	0,69	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,6	0,9	2,14	7,99	P	0,68	P	0,88	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6537	6537	G	T	MI.3217	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	634	212	D	Y	Gac/Tac	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,38	deleterious	-5,8	deleterious	-7,81	high_impact	5,3	damaging	0,5	damaging	0,07	deleterious	3,87	23,5	0,22	0,55	disease	0,87	disease	0,95	disease	0,79	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,41	0,9	3,12	6,68	P	0,53	P	0,94	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6537	6537	G	C	MI.3218	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	634	212	D	H	Gac/Cac	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-4,04	deleterious	-6,07	high_impact	4,96	damaging	0,54	damaging	0,07	deleterious	3,63	23,2	0,32	0,55	disease	0,8	disease	0,91	disease	0,84	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,44	0,9	3,12	6,68	P	0,65	P	0,97	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6537	6537	G	A	MI.3219	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	634	212	D	N	Gac/Aac	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,51	neutral	-2,43	deleterious	-4,34	high_impact	4,96	damaging	0,38	damaging	0,09	deleterious	4,19	23,8	0,63	0,65	disease	0,62	disease	0,89	disease	0,76	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,81	0,9	3,12	6,68	P	0,69	P	0,89	disease_causing	0,99	0,48	.	.	.	.	.	.	COSM5653111	.	.	.	.	.	.	.	.
chrM	8676	8676	C	G	MI.322	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	150	50	I	M	atC/atG	1,98	0,02	0	possibly_damaging	0,66	neutral	0,16	neutral	4,28	neutral	-1,48	neutral	-1,92	low_impact	1,16	neutral	0,88	neutral	0,68	neutral	1,8	14,98	0,56	0,65	disease	0,71	neutral	0,31	neutral	0,2	disease	0,63	3	neutral	0,86	neutral	0,25	neutral	-3	deleterious	0,59	low_impact	-1,03	medium_impact	-0,12	medium_impact	-0,1	0,75	0,9	17,7	19,1	N	0,45	N	0,6	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6538	6538	A	C	MI.3220	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	635	212	D	A	gAc/gCc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,43	deleterious	-3,8	deleterious	-6,94	high_impact	5,3	neutral	0,62	damaging	0,1	deleterious	3,6	23,2	0,28	0,55	disease	0,64	disease	0,87	disease	0,77	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,49	0,9	3,12	6,68	P	0,73	P	0,85	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6538	6538	A	T	MI.3221	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	635	212	D	V	gAc/gTc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,4	deleterious	-4,96	deleterious	-7,81	high_impact	4,96	damaging	0,48	damaging	0,08	deleterious	3,71	23,3	0,23	0,55	disease	0,79	disease	0,93	disease	0,76	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,36	0,9	3,12	6,68	P	0,59	P	0,93	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6538	6538	A	G	MI.3222	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	635	212	D	G	gAc/gGc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-3,46	deleterious	-6,07	high_impact	5,3	damaging	0,49	damaging	0,1	deleterious	3,95	23,6	0,35	0,55	disease	0,73	disease	0,92	disease	0,77	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,39	0,9	3,12	6,68	P	0,7	P	0,85	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6539	6539	C	G	MI.3223	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	636	212	D	E	gaC/gaG	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,52	neutral	-2,35	deleterious	-3,47	high_impact	4,41	damaging	0,46	damaging	0,09	deleterious	3,91	23,5	0,54	0,6	neutral	0,33	disease	0,87	disease	0,75	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,97	0,61	0,9	3,12	6,68	P	0,59	P	0,65	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6539	6539	C	A	MI.3224	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	636	212	D	E	gaC/gaA	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,52	neutral	-2,35	deleterious	-3,47	high_impact	4,41	damaging	0,46	damaging	0,09	deleterious	4,21	23,9	0,54	0,6	neutral	0,33	disease	0,87	disease	0,75	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,97	0,61	0,9	3,12	6,68	P	0,61	P	0,65	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6540	6540	C	T	MI.3225	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	637	213	R	C	Cgc/Tgc	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-5,09	deleterious	-6,94	high_impact	5,29	damaging	0,49	damaging	0,1	deleterious	4,98	25,1	0,26	0,55	disease	0,91	disease	0,85	disease	0,73	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,82	0,9	2,14	6,91	P	0,54	P	1	disease_causing	0,98	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6540	6540	C	A	MI.3226	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	637	213	R	S	Cgc/Agc	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-3,25	deleterious	-5,2	high_impact	4,59	damaging	0,58	damaging	0,21	deleterious	4,7	24,6	0,24	0,55	disease	0,61	disease	0,81	disease	0,66	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,14	0,47	0,9	2,14	6,91	N	0,42	N	0,8	polymorphism	0,84	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6540	6540	C	G	MI.3227	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	637	213	R	G	Cgc/Ggc	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-3,86	deleterious	-6,07	high_impact	5,29	damaging	0,5	damaging	0,25	deleterious	4,19	23,8	0,24	0,55	disease	0,75	disease	0,76	disease	0,73	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,37	0,9	2,14	6,91	P	0,61	P	0,92	polymorphism	0,85	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6541	6541	G	C	MI.3228	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	638	213	R	P	cGc/cCc	3,6	0,99	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-3,36	deleterious	-6,08	high_impact	4,59	damaging	0,42	damaging	0,15	deleterious	4,27	24	0,17	0,55	disease	0,8	disease	0,84	disease	0,71	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,14	0,38	0,9	2,14	6,91	P	0,64	P	0,99	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6541	6541	G	A	MI.3229	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	638	213	R	H	cGc/cAc	3,6	0,99	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-4,2	deleterious	-4,34	high_impact	4,94	damaging	0,51	damaging	0,08	deleterious	4,41	24,1	0,41	0,55	disease	0,76	disease	0,8	disease	0,68	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,46	0,86	0,9	2,14	6,91	P	0,68	P	0,98	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8677	8677	A	G	MI.323	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	151	51	K	E	Aaa/Gaa	-8,89	0	0	benign	0,01	neutral	0,73	neutral	4,46	neutral	0,57	neutral	-0,83	neutral_impact	0,34	neutral	0,88	neutral	0,52	deleterious	0,69	8,77	0,47	0,65	neutral	0,29	disease	0,64	neutral	0,38	disease	0,53	1	neutral	0,25	deleterious	0,86	neutral	-6	neutral	0,17	medium_impact	1,14	medium_impact	0,54	medium_impact	-0,81	0,73	0,9	20,8	18,4	N	0,26	N	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6541	6541	G	T	MI.3230	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	638	213	R	L	cGc/cTc	3,6	0,99	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-1,89	deleterious	-6,07	high_impact	3,67	damaging	0,52	damaging	0,22	deleterious	4,34	24	0,28	0,55	neutral	0,38	disease	0,89	disease	0,71	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,29	0,37	0,9	2,14	6,91	P	0,5	N	0,99	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6543	6543	A	G	MI.3231	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	640	214	N	D	Aac/Gac	-7,74	0	0	probably_damaging	0,99	deleterious	0	neutral	2,75	deleterious	-3,59	deleterious	-4,33	high_impact	4,64	damaging	0,49	damaging	0,19	deleterious	3,92	23,5	0,58	0,65	neutral	0,41	disease	0,76	disease	0,55	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-2,64	low_impact	-1,48	high_impact	3,19	0,52	0,9	2,53	7,24	N	0,48	N	0,92	polymorphism	0,99	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6543	6543	A	C	MI.3232	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	640	214	N	H	Aac/Cac	-7,74	0	0	probably_damaging	1	neutral	0,06	neutral	2,81	neutral	-1,82	deleterious	-4,33	medium_impact	3,13	neutral	0,62	damaging	0,11	deleterious	3,17	22,7	0,44	0,55	neutral	0,36	disease	0,82	disease	0,56	disease	0,58	2	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,76	low_impact	-3,58	medium_impact	-0,47	medium_impact	1,79	0,49	0,9	2,53	7,24	N	0,29	N	0,83	polymorphism	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6543	6543	A	T	MI.3233	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	640	214	N	Y	Aac/Tac	-7,74	0	0	probably_damaging	1	deleterious	0	neutral	2,81	neutral	-1,77	deleterious	-6,93	high_impact	4,64	neutral	0,62	damaging	0,12	deleterious	3,77	23,4	0,28	0,55	disease	0,52	disease	0,87	disease	0,58	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,19	0,36	0,9	2,53	7,24	N	0,45	N	0,93	polymorphism	0,95	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6544	6544	A	T	MI.3234	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	641	214	N	I	aAc/aTc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,82	neutral	-1,64	deleterious	-7,8	high_impact	4,22	neutral	0,62	damaging	0,12	deleterious	4,47	24,2	0,29	0,55	disease	0,58	disease	0,9	disease	0,61	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,8	0,33	0,9	2,53	7,24	N	0,49	N	0,98	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6544	6544	A	G	MI.3235	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	641	214	N	S	aAc/aGc	8,69	1	0	probably_damaging	0,98	deleterious	0	neutral	2,84	neutral	-1,28	deleterious	-4,33	high_impact	4,04	neutral	0,66	damaging	0,14	deleterious	3,61	23,2	0,58	0,65	neutral	0,18	disease	0,81	disease	0,54	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,35	low_impact	-1,48	high_impact	2,63	0,31	0,9	2,53	7,24	N	0,48	N	0,79	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6544	6544	A	C	MI.3236	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	641	214	N	T	aAc/aCc	8,69	1	0	probably_damaging	1	deleterious	0,03	neutral	2,79	neutral	-2,13	deleterious	-5,19	high_impact	4	neutral	0,63	damaging	0,13	deleterious	3,88	23,5	0,43	0,55	neutral	0,31	disease	0,82	disease	0,62	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,75	low_impact	-3,58	medium_impact	-0,65	high_impact	2,59	0,44	0,9	2,53	7,24	N	0,45	N	0,59	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6545	6545	C	A	MI.3237	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	642	214	N	K	aaC/aaA	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,77	neutral	-2,65	deleterious	-5,2	high_impact	3,69	damaging	0,57	damaging	0,11	deleterious	4,51	24,3	0,61	0,65	neutral	0,23	disease	0,87	disease	0,6	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,31	0,64	0,9	2,53	7,24	N	0,43	N	0,92	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6545	6545	C	G	MI.3238	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	642	214	N	K	aaC/aaG	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,77	neutral	-2,65	deleterious	-5,2	high_impact	3,69	damaging	0,57	damaging	0,11	deleterious	4,03	23,7	0,61	0,65	neutral	0,23	disease	0,87	disease	0,6	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,31	0,64	0,9	2,53	7,24	N	0,41	N	0,92	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6546	6546	C	G	MI.3239	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	643	215	L	V	Ctc/Gtc	-3,11	0	0	benign	0,09	deleterious	0,04	neutral	2,77	neutral	-1,72	neutral	-1,61	medium_impact	2,73	damaging	0,52	neutral	0,36	neutral	1,53	13,49	0,45	0,55	disease	0,57	disease	0,55	neutral	0,44	disease	0,5	0	neutral	0,96	deleterious	0,48	deleterious	1	neutral	0,28	medium_impact	0,19	medium_impact	-0,58	medium_impact	1,42	0,61	0,9	5,65	8,72	N	0,42	N	0,66	polymorphism	0,87	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8677	8677	A	C	MI.324	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	151	51	K	Q	Aaa/Caa	-8,89	0	0	benign	0	neutral	0,62	neutral	4,34	neutral	-0,71	neutral	0,15	neutral_impact	0,7	neutral	0,95	neutral	0,98	neutral	-0,74	0,06	0,52	0,65	neutral	0,45	neutral	0,33	neutral	0,21	neutral	0,47	1	neutral	0,38	deleterious	0,81	neutral	-6	neutral	0,15	high_impact	2,09	medium_impact	0,41	medium_impact	-0,5	0,61	0,9	20,8	18,4	N	0,39	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6546	6546	C	T	MI.3240	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	643	215	L	F	Ctc/Ttc	-3,11	0	0	benign	0,01	neutral	0,69	neutral	2,94	neutral	-0,84	neutral	-0,45	neutral_impact	-0,14	damaging	0,57	neutral	0,58	deleterious	0,34	6,11	0,39	0,55	neutral	0,25	neutral	0,13	neutral	0,16	neutral	0,25	5	neutral	0,28	deleterious	0,84	neutral	-6	neutral	0,16	medium_impact	1,12	medium_impact	0,39	low_impact	-1,23	0,58	0,9	5,65	8,72	N	0,4	N	0,87	polymorphism	0,57	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6546	6546	C	A	MI.3241	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	643	215	L	I	Ctc/Atc	-3,11	0	0	benign	0,21	neutral	0,09	neutral	2,76	neutral	-2,18	neutral	-0,81	low_impact	1,68	neutral	0,63	neutral	0,66	neutral	1,2	11,76	0,39	0,55	neutral	0,49	neutral	0,34	neutral	0,25	neutral	0,44	1	neutral	0,9	neutral	0,44	neutral	-6	neutral	0,25	medium_impact	-0,22	medium_impact	-0,37	medium_impact	0,45	0,72	0,9	5,65	8,72	N	0,51	P	0,54	polymorphism	0,92	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6547	6547	T	G	MI.3242	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	644	215	L	R	cTc/cGc	0,13	0	0	possibly_damaging	0,81	deleterious	0	neutral	2,7	deleterious	-4,38	deleterious	-4,18	high_impact	4,08	damaging	0,54	damaging	0,27	deleterious	4,07	23,7	0,2	0,55	disease	0,88	disease	0,91	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,1	deleterious	5	deleterious	0,83	low_impact	-1,35	low_impact	-1,48	high_impact	2,67	0,55	0,9	5,65	8,72	N	0,34	N	0,9	polymorphism	0,85	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6547	6547	T	C	MI.3243	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	644	215	L	P	cTc/cCc	0,13	0	0	probably_damaging	0,93	deleterious	0	neutral	2,69	deleterious	-4,96	deleterious	-4,95	high_impact	4,43	damaging	0,49	neutral	0,39	deleterious	3,86	23,5	0,16	0,55	disease	0,9	disease	0,89	disease	0,59	disease	0,79	6	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,9	low_impact	-1,81	low_impact	-1,48	high_impact	2,99	0,52	0,9	5,65	8,72	N	0,44	N	0,83	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6547	6547	T	A	MI.3244	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	644	215	L	H	cTc/cAc	0,13	0	0	possibly_damaging	0,86	deleterious	0	neutral	2,69	deleterious	-4,92	deleterious	-4,12	high_impact	4,08	damaging	0,57	damaging	0,28	deleterious	4,04	23,7	0,2	0,55	disease	0,91	disease	0,81	disease	0,68	disease	0,79	6	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,82	low_impact	-1,5	low_impact	-1,48	high_impact	2,67	0,54	0,9	5,65	8,72	N	0,32	N	0,83	polymorphism	0,91	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6549	6549	A	G	MI.3245	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	646	216	N	D	Aac/Gac	-7,04	0	0	probably_damaging	0,99	deleterious	0	neutral	2,78	neutral	-1,67	deleterious	-4,32	high_impact	4,29	damaging	0,56	damaging	0,15	deleterious	3,85	23,4	0,73	0,75	neutral	0,29	disease	0,74	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,71	low_impact	-2,64	low_impact	-1,48	high_impact	2,86	0,59	0,9	2,73	6,98	N	0,35	N	0,92	polymorphism	0,99	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6549	6549	A	T	MI.3246	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	646	216	N	Y	Aac/Tac	-7,04	0	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,89	deleterious	-6,91	high_impact	5,19	damaging	0,59	damaging	0,13	deleterious	3,74	23,3	0,36	0,55	disease	0,71	disease	0,85	disease	0,73	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,43	0,9	2,73	6,98	P	0,62	P	0,93	polymorphism	0,95	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6549	6549	A	C	MI.3247	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	646	216	N	H	Aac/Cac	-7,04	0	0	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-3,02	deleterious	-4,32	high_impact	4,5	damaging	0,48	damaging	0,15	deleterious	3,11	22,5	0,54	0,6	neutral	0,48	disease	0,81	disease	0,72	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,48	0,9	2,73	6,98	N	0,47	N	0,83	polymorphism	0,99	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6550	6550	A	G	MI.3248	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	647	216	N	S	aAc/aGc	8,69	1	0	probably_damaging	0,98	neutral	0,06	neutral	2,77	neutral	-1,77	deleterious	-4,31	high_impact	3,77	neutral	0,63	damaging	0,15	deleterious	3,11	22,5	0,73	0,75	neutral	0,38	disease	0,77	disease	0,6	disease	0,62	2	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,74	low_impact	-2,35	medium_impact	-0,47	high_impact	2,38	0,34	0,9	2,73	6,98	P	0,53	P	0,79	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6550	6550	A	C	MI.3249	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	647	216	N	T	aAc/aCc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,73	neutral	-2,5	deleterious	-5,18	high_impact	4,84	damaging	0,58	damaging	0,15	deleterious	3,39	23	0,47	0,55	neutral	0,44	disease	0,8	disease	0,68	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,34	0,9	2,73	6,98	P	0,68	P	0,59	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8678	8678	A	C	MI.325	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	152	51	K	T	aAa/aCa	-2,19	0	0	benign	0,02	neutral	0,49	neutral	4,31	neutral	-1,2	neutral	-2,06	low_impact	1,23	neutral	0,91	neutral	0,79	deleterious	0,34	6,07	0,32	0,65	neutral	0,48	neutral	0,37	neutral	0,35	neutral	0,43	1	neutral	0,48	deleterious	0,74	neutral	-6	neutral	0,18	medium_impact	0,85	medium_impact	0,28	medium_impact	-0,04	0,44	0,9	20,8	18,4	N	0,32	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6550	6550	A	T	MI.3250	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	647	216	N	I	aAc/aTc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,68	deleterious	-5,1	deleterious	-7,78	high_impact	5,19	damaging	0,59	damaging	0,13	deleterious	4,03	23,6	0,32	0,55	disease	0,66	disease	0,88	disease	0,68	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,34	0,9	2,73	6,98	P	0,64	P	0,98	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6551	6551	C	A	MI.3251	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	648	216	N	K	aaC/aaA	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,74	neutral	-2,38	deleterious	-5,18	high_impact	5,19	damaging	0,54	damaging	0,11	deleterious	4,39	24,1	0,66	0,7	neutral	0,33	disease	0,86	disease	0,7	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,61	0,9	2,73	6,98	P	0,65	P	0,92	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6551	6551	C	G	MI.3252	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	648	216	N	K	aaC/aaG	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,74	neutral	-2,38	deleterious	-5,18	high_impact	5,19	damaging	0,54	damaging	0,11	deleterious	3,94	23,5	0,66	0,7	neutral	0,33	disease	0,86	disease	0,7	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,61	0,9	2,73	6,98	P	0,65	P	0,92	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6552	6552	A	T	MI.3253	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	649	217	T	S	Acc/Tcc	-5,66	0	0	probably_damaging	0,99	neutral	0,1	neutral	2,58	neutral	-2,77	deleterious	-3,39	medium_impact	2,4	neutral	0,72	damaging	0,08	deleterious	3,16	22,6	0,52	0,6	disease	0,61	disease	0,68	neutral	0,41	neutral	0,45	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,78	low_impact	-2,64	medium_impact	-0,34	medium_impact	1,12	0,75	0,9	2,53	6,67	N	0,25	N	0,79	polymorphism	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6552	6552	A	C	MI.3254	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	649	217	T	P	Acc/Ccc	-5,66	0	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-3,92	deleterious	-5,17	high_impact	5,2	damaging	0,59	damaging	0,08	deleterious	3,4	23	0,27	0,55	disease	0,81	disease	0,83	disease	0,7	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,7	0,5	0,9	2,53	6,67	P	0,61	P	0,92	polymorphism	0,91	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6552	6552	A	G	MI.3255	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	649	217	T	A	Acc/Gcc	-5,66	0	0	probably_damaging	0,99	deleterious	0	neutral	2,62	neutral	-1,98	deleterious	-4,28	medium_impact	3,33	neutral	0,74	damaging	0,07	deleterious	3,37	22,9	0,49	0,55	neutral	0,36	disease	0,69	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,73	low_impact	-2,64	low_impact	-1,48	medium_impact	1,98	0,56	0,9	2,53	6,67	N	0,29	N	0,69	polymorphism	0,98	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6553	6553	C	G	MI.3256	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	650	217	T	S	aCc/aGc	8,69	1	0	probably_damaging	0,99	neutral	0,1	neutral	2,58	neutral	-2,77	deleterious	-3,39	medium_impact	2,4	neutral	0,72	damaging	0,08	deleterious	3,51	23,1	0,52	0,6	disease	0,61	disease	0,68	neutral	0,41	neutral	0,45	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,78	low_impact	-2,64	medium_impact	-0,34	medium_impact	1,12	0,75	0,9	2,53	6,67	N	0,49	N	0,79	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6553	6553	C	A	MI.3257	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	650	217	T	N	aCc/aAc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-4,2	deleterious	-4,29	high_impact	5,2	neutral	0,66	damaging	0,06	deleterious	3,71	23,3	0,43	0,55	disease	0,76	disease	0,86	disease	0,71	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,7	0,8	0,9	2,53	6,67	P	0,73	P	0,8	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6553	6553	C	T	MI.3258	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	650	217	T	I	aCc/aTc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-1,85	deleterious	-5,17	high_impact	4,5	neutral	0,7	damaging	0,06	deleterious	4,01	23,6	0,33	0,55	neutral	0,43	disease	0,85	disease	0,71	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,62	0,9	2,53	6,67	P	0,51	P	0,92	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6555	6555	A	T	MI.3259	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	652	218	T	S	Acc/Tcc	-15,14	0	0	benign	0	neutral	1	neutral	3,29	neutral	1,93	neutral	1,33	neutral_impact	-1,4	neutral	0,65	damaging	0,28	neutral	1,1	11,2	0,39	0,55	neutral	0,18	neutral	0,06	neutral	0,21	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,07	high_impact	1,86	low_impact	-2,39	0,71	0,9	4,48	10,9	N	0,36	N	0,79	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8678	8678	A	T	MI.326	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	152	51	K	M	aAa/aTa	-2,19	0	0	benign	0,28	neutral	0,16	neutral	4,26	deleterious	-3,14	neutral	-2,18	neutral_impact	0,5	neutral	0,86	neutral	0,74	neutral	1,01	10,73	0,35	0,65	disease	0,55	neutral	0,4	neutral	0,24	disease	0,6	2	neutral	0,81	neutral	0,44	neutral	-6	neutral	0,34	medium_impact	-0,37	medium_impact	-0,12	medium_impact	-0,67	0,52	0,9	20,8	18,4	N	0,4	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6555	6555	A	G	MI.3260	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	652	218	T	A	Acc/Gcc	-15,14	0	0	benign	0,03	deleterious	0,02	neutral	2,99	neutral	-0,08	neutral	-0,69	low_impact	1,05	neutral	0,68	damaging	0,2	deleterious	3,96	23,6	0,44	0,55	neutral	0,25	disease	0,5	neutral	0,34	neutral	0,44	1	neutral	0,98	deleterious	0,5	neutral	-2	neutral	0,17	medium_impact	0,66	medium_impact	-0,75	medium_impact	-0,13	0,41	0,9	4,48	10,9	N	0,43	N	0,69	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6555	6555	A	C	MI.3261	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	652	218	T	P	Acc/Ccc	-15,14	0	0	possibly_damaging	0,46	deleterious	0	neutral	2,94	neutral	-1,11	neutral	-2,38	medium_impact	3,21	damaging	0,58	damaging	0,15	deleterious	3,98	23,6	0,16	0,55	neutral	0,4	disease	0,88	disease	0,6	disease	0,76	5	deleterious	1	neutral	0,27	deleterious	4	deleterious	0,59	medium_impact	-0,69	low_impact	-1,48	medium_impact	1,87	0,54	0,9	4,48	10,9	N	0,32	N	0,92	polymorphism	0,98	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6556	6556	C	G	MI.3262	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	653	218	T	S	aCc/aGc	3,37	0,99	0	benign	0	neutral	1	neutral	3,29	neutral	1,93	neutral	1,33	neutral_impact	-1,4	neutral	0,65	damaging	0,28	deleterious	0,82	9,58	0,39	0,55	neutral	0,18	neutral	0,06	neutral	0,21	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,07	high_impact	1,86	low_impact	-2,39	0,71	0,9	4,48	10,9	N	0,43	N	0,79	disease_causing	0,97	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6556	6556	C	T	MI.3263	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	653	218	T	I	aCc/aTc	3,37	0,99	0	possibly_damaging	0,57	deleterious	0	neutral	2,92	neutral	-1,52	deleterious	-3,03	medium_impact	3,21	neutral	0,64	damaging	0,13	deleterious	4,03	23,6	0,29	0,55	neutral	0,45	disease	0,73	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,22	deleterious	4	deleterious	0,64	medium_impact	-0,87	low_impact	-1,48	medium_impact	1,87	0,65	0,9	4,48	10,9	N	0,4	N	0,92	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6556	6556	C	A	MI.3264	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	653	218	T	N	aCc/aAc	3,37	0,99	0	benign	0,2	deleterious	0	neutral	2,95	neutral	-0,92	neutral	-0,93	medium_impact	2,46	neutral	0,62	damaging	0,11	deleterious	3,72	23,3	0,39	0,55	neutral	0,3	disease	0,84	disease	0,62	disease	0,75	5	deleterious	1	neutral	0,4	deleterious	1	neutral	0,32	medium_impact	-0,19	low_impact	-1,48	medium_impact	1,17	0,72	0,9	4,48	10,9	N	0,39	N	0,8	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6558	6558	T	A	MI.3265	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	655	219	F	I	Ttc/Atc	-13,98	0	0	probably_damaging	1	deleterious	0	neutral	2,51	neutral	-2,27	deleterious	-5,19	high_impact	3,66	neutral	0,63	damaging	0,14	deleterious	4,45	24,2	0,2	0,55	neutral	0,36	disease	0,8	disease	0,74	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,28	0,69	0,9	3,31	7,66	N	0,3	N	0,88	polymorphism	0,93	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6558	6558	T	G	MI.3266	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	655	219	F	V	Ttc/Gtc	-13,98	0	0	probably_damaging	1	deleterious	0	neutral	2,49	neutral	-2,28	deleterious	-6,06	medium_impact	3,49	damaging	0,56	damaging	0,11	deleterious	4,16	23,8	0,27	0,55	neutral	0,45	disease	0,86	disease	0,75	disease	0,77	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,12	0,59	0,9	3,31	7,66	N	0,32	N	0,84	polymorphism	0,85	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6558	6558	T	C	MI.3267	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	655	219	F	L	Ttc/Ctc	-13,98	0	0	probably_damaging	1	deleterious	0	neutral	2,51	neutral	-1,89	deleterious	-5,19	high_impact	4,28	damaging	0,53	damaging	0,15	deleterious	4,1	23,7	0,44	0,55	neutral	0,35	disease	0,8	disease	0,67	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	2,85	0,74	0,9	3,31	7,66	N	0,38	N	0,83	polymorphism	0,92	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6559	6559	T	C	MI.3268	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	656	219	F	S	tTc/tCc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-3,28	deleterious	-6,92	high_impact	5,25	neutral	0,67	damaging	0,14	deleterious	4,26	23,9	0,22	0,55	disease	0,75	disease	0,88	disease	0,72	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,75	0,52	0,9	3,31	7,66	P	0,72	P	0,84	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6559	6559	T	A	MI.3269	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	656	219	F	Y	tTc/tAc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-3,29	deleterious	-2,6	high_impact	3,94	damaging	0,6	damaging	0,11	deleterious	4,25	23,9	0,28	0,55	disease	0,64	disease	0,78	disease	0,69	disease	0,63	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,54	0,75	0,9	3,31	7,66	P	0,55	P	0,59	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8679	8679	A	T	MI.327	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	153	51	K	N	aaA/aaT	1,05	0	0	benign	0,02	neutral	0,71	neutral	4,36	neutral	-0,43	neutral	-0,35	neutral_impact	-0,64	neutral	0,82	neutral	0,87	neutral	-0,91	0,03	0,61	0,7	neutral	0,31	neutral	0,17	neutral	0,2	neutral	0,29	4	neutral	0,24	deleterious	0,85	neutral	-6	neutral	0,15	medium_impact	0,85	medium_impact	0,51	low_impact	-1,65	0,69	0,9	20,8	18,4	N	0,33	N	0,48	polymorphism	1	0,01	rs386829045	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6559	6559	T	G	MI.3270	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	656	219	F	C	tTc/tGc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,37	deleterious	-5,05	deleterious	-6,93	high_impact	4,56	damaging	0,58	damaging	0,11	deleterious	4,14	23,8	0,24	0,55	disease	0,86	disease	0,89	disease	0,77	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,11	0,42	0,9	3,31	7,66	P	0,56	P	0,91	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6560	6560	C	A	MI.3271	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	657	219	F	L	ttC/ttA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,51	neutral	-1,89	deleterious	-5,19	high_impact	4,28	damaging	0,53	damaging	0,15	deleterious	4,7	24,6	0,44	0,55	neutral	0,35	disease	0,8	disease	0,67	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	2,85	0,74	0,9	3,31	7,66	P	0,54	P	0,83	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6560	6560	C	G	MI.3272	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	657	219	F	L	ttC/ttG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,51	neutral	-1,89	deleterious	-5,19	high_impact	4,28	damaging	0,53	damaging	0,15	deleterious	4,4	24,1	0,44	0,55	neutral	0,35	disease	0,8	disease	0,67	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	2,85	0,74	0,9	3,31	7,66	P	0,54	P	0,83	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6561	6561	T	G	MI.3273	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	658	220	F	V	Ttc/Gtc	-0,8	0,02	0	probably_damaging	1	deleterious	0	neutral	2,3	deleterious	-3,06	deleterious	-6	high_impact	5,25	neutral	0,64	damaging	0,16	deleterious	4,06	23,7	0,26	0,55	disease	0,75	disease	0,88	disease	0,76	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,75	0,66	0,9	5,46	8,27	P	0,7	P	0,84	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6561	6561	T	A	MI.3274	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	658	220	F	I	Ttc/Atc	-0,8	0,02	0	probably_damaging	0,99	deleterious	0	neutral	2,38	neutral	-2,12	deleterious	-5,15	high_impact	5,25	neutral	0,71	damaging	0,18	deleterious	4,36	24,1	0,21	0,55	disease	0,78	disease	0,82	disease	0,76	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	3,75	0,71	0,9	5,46	8,27	P	0,69	P	0,88	disease_causing	0,99	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6561	6561	T	C	MI.3275	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	658	220	F	L	Ttc/Ctc	-0,8	0,02	0	probably_damaging	0,99	deleterious	0,03	neutral	2,35	neutral	-2,35	deleterious	-5,15	high_impact	4,45	damaging	0,57	damaging	0,19	deleterious	4	23,6	0,42	0,55	disease	0,7	disease	0,81	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-2,64	medium_impact	-0,65	high_impact	3,01	0,79	0,9	5,46	8,27	N	0,45	N	0,83	disease_causing	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6562	6562	T	A	MI.3276	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	659	220	F	Y	tTc/tAc	7,53	1	0	probably_damaging	0,99	neutral	0,11	neutral	2,41	neutral	-1,8	neutral	-2,49	medium_impact	2,73	neutral	0,69	damaging	0,16	deleterious	4,33	24	0,25	0,55	disease	0,55	disease	0,74	neutral	0,48	neutral	0,49	0	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,8	low_impact	-2,64	medium_impact	-0,31	medium_impact	1,42	0,79	0,9	5,46	8,27	P	0,57	P	0,59	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6562	6562	T	G	MI.3277	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	659	220	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,23	deleterious	-5,62	deleterious	-6,87	high_impact	5,25	neutral	0,67	damaging	0,16	deleterious	4,16	23,8	0,18	0,55	disease	0,92	disease	0,9	disease	0,77	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,75	0,41	0,9	5,46	8,27	P	0,68	P	0,91	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6562	6562	T	C	MI.3278	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	659	220	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,26	deleterious	-4,18	deleterious	-6,86	high_impact	4,7	neutral	0,76	damaging	0,2	deleterious	4,3	24	0,16	0,55	disease	0,72	disease	0,89	disease	0,75	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,24	0,42	0,9	5,46	8,27	P	0,62	P	0,84	disease_causing	1	0,48	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	6563	6563	C	A	MI.3279	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	660	220	F	L	ttC/ttA	7,53	1	0	probably_damaging	0,99	deleterious	0,03	neutral	2,35	neutral	-2,35	deleterious	-5,15	high_impact	4,45	damaging	0,57	damaging	0,19	deleterious	4,64	24,5	0,42	0,55	disease	0,7	disease	0,81	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-2,64	medium_impact	-0,65	high_impact	3,01	0,79	0,9	5,46	8,27	P	0,6	P	0,83	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8679	8679	A	C	MI.328	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	153	51	K	N	aaA/aaC	1,05	0	0	benign	0,02	neutral	0,71	neutral	4,36	neutral	-0,43	neutral	-0,35	neutral_impact	-0,64	neutral	0,82	neutral	0,87	neutral	-0,97	0,02	0,61	0,7	neutral	0,31	neutral	0,17	neutral	0,2	neutral	0,29	4	neutral	0,24	deleterious	0,85	neutral	-6	neutral	0,15	medium_impact	0,85	medium_impact	0,51	low_impact	-1,65	0,69	0,9	20,8	18,4	N	0,33	N	0,48	polymorphism	1	0,01	rs386829045	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6563	6563	C	G	MI.3280	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	660	220	F	L	ttC/ttG	7,53	1	0	probably_damaging	0,99	deleterious	0,03	neutral	2,35	neutral	-2,35	deleterious	-5,15	high_impact	4,45	damaging	0,57	damaging	0,19	deleterious	4,36	24,1	0,42	0,55	disease	0,7	disease	0,81	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-2,64	medium_impact	-0,65	high_impact	3,01	0,79	0,9	5,46	8,27	P	0,6	P	0,83	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6564	6564	G	A	MI.3281	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	661	221	D	N	Gac/Aac	-3,8	0	0	probably_damaging	0,99	deleterious	0	neutral	2,81	neutral	-1,31	deleterious	-4,3	medium_impact	3,46	damaging	0,49	damaging	0,1	deleterious	4,19	23,8	0,45	0,55	neutral	0,29	disease	0,9	neutral	0,49	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	2,1	0,58	0,9	6,43	8,01	N	0,35	N	0,89	polymorphism	0,64	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6564	6564	G	T	MI.3282	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	661	221	D	Y	Gac/Tac	-3,8	0	0	probably_damaging	1	deleterious	0	neutral	2,81	deleterious	-3,9	deleterious	-7,76	high_impact	4,16	damaging	0,57	damaging	0,1	deleterious	3,9	23,5	0,2	0,55	disease	0,75	disease	0,95	disease	0,67	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,74	0,4	0,9	6,43	8,01	N	0,32	N	0,94	disease_causing	0,86	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6564	6564	G	C	MI.3283	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	661	221	D	H	Gac/Cac	-3,8	0	0	probably_damaging	1	deleterious	0	neutral	2,76	deleterious	-3,13	deleterious	-6,04	high_impact	4,86	damaging	0,5	damaging	0,11	deleterious	3,62	23,2	0,24	0,55	disease	0,64	disease	0,92	disease	0,67	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,39	0,45	0,9	6,43	8,01	P	0,6	P	0,97	disease_causing	0,75	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6565	6565	A	C	MI.3284	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	662	221	D	A	gAc/gCc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,87	neutral	-1,24	deleterious	-6,89	high_impact	3,92	neutral	0,68	damaging	0,13	deleterious	4,17	23,8	0,2	0,55	neutral	0,41	disease	0,89	disease	0,65	disease	0,51	0	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,52	0,48	0,9	6,43	8,01	N	0,48	N	0,85	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6565	6565	A	T	MI.3285	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	662	221	D	V	gAc/gTc	7,3	1	0	probably_damaging	1	deleterious	0,03	neutral	2,86	neutral	-2,26	deleterious	-7,76	high_impact	4,16	damaging	0,54	damaging	0,1	deleterious	4,36	24,1	0,18	0,55	disease	0,64	disease	0,95	disease	0,67	disease	0,79	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-3,58	medium_impact	-0,65	high_impact	2,74	0,35	0,9	6,43	8,01	N	0,48	N	0,93	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6565	6565	A	G	MI.3286	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	662	221	D	G	gAc/gGc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,77	neutral	-2,05	deleterious	-6,04	high_impact	5,2	damaging	0,55	damaging	0,12	deleterious	4,56	24,4	0,19	0,55	disease	0,59	disease	0,9	disease	0,65	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,7	0,39	0,9	6,43	8,01	P	0,68	P	0,85	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6566	6566	C	A	MI.3287	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	663	221	D	E	gaC/gaA	6,84	1	0	probably_damaging	0,97	deleterious	0,01	neutral	2,79	neutral	-1	deleterious	-3,44	medium_impact	3,11	damaging	0,48	damaging	0,14	deleterious	4,21	23,9	0,39	0,55	neutral	0,25	disease	0,84	neutral	0,31	neutral	0,47	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,74	low_impact	-2,18	medium_impact	-0,92	medium_impact	1,77	0,49	0,9	6,43	8,01	P	0,52	P	0,65	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6566	6566	C	G	MI.3288	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	663	221	D	E	gaC/gaG	6,84	1	0	probably_damaging	0,97	deleterious	0,01	neutral	2,79	neutral	-1	deleterious	-3,44	medium_impact	3,11	damaging	0,48	damaging	0,14	deleterious	3,89	23,5	0,39	0,55	neutral	0,25	disease	0,84	neutral	0,31	neutral	0,47	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,74	low_impact	-2,18	medium_impact	-0,92	medium_impact	1,77	0,49	0,9	6,43	8,01	P	0,52	P	0,65	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6567	6567	C	G	MI.3289	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	664	222	P	A	Ccc/Gcc	-1,03	0,02	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-1,69	deleterious	-6,78	high_impact	3,65	neutral	0,69	damaging	0,07	deleterious	3,09	22,5	0,24	0,55	neutral	0,42	disease	0,75	disease	0,58	disease	0,59	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,27	0,8	0,9	2,53	6,7	N	0,3	N	0,76	disease_causing	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8680	8680	C	G	MI.329	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	154	52	L	V	Cta/Gta	-1,03	0	0	benign	0,32	neutral	0,58	neutral	4,36	neutral	-0,54	neutral	-1,72	low_impact	1,07	neutral	0,92	neutral	0,6	neutral	-0,08	1,88	0,51	0,65	disease	0,59	neutral	0,33	neutral	0,28	disease	0,6	2	neutral	0,33	deleterious	0,63	neutral	-6	deleterious	0,46	medium_impact	-0,45	medium_impact	0,37	medium_impact	-0,18	0,58	0,9	12,83	8,79	N	0,28	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6567	6567	C	T	MI.3290	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	664	222	P	S	Ccc/Tcc	-1,03	0,02	0	probably_damaging	1	deleterious	0,03	neutral	2,73	neutral	-2,72	deleterious	-6,81	high_impact	3,8	neutral	0,69	damaging	0,05	deleterious	3,88	23,5	0,32	0,55	neutral	0,48	disease	0,87	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,81	low_impact	-3,58	medium_impact	-0,65	high_impact	2,41	0,21	0,9	2,53	6,7	N	0,33	N	0,85	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6567	6567	C	A	MI.3291	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	664	222	P	T	Ccc/Acc	-1,03	0,02	0	probably_damaging	1	deleterious	0,04	neutral	2,74	neutral	-2,35	deleterious	-6,79	high_impact	4,09	neutral	0,67	damaging	0,06	deleterious	3,84	23,4	0,3	0,55	neutral	0,48	disease	0,87	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-3,58	medium_impact	-0,58	high_impact	2,68	0,75	0,9	2,53	6,7	N	0,35	N	0,8	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6568	6568	C	T	MI.3292	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	665	222	P	L	cCc/cTc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,79	neutral	-1,58	deleterious	-8,51	high_impact	4,7	neutral	0,7	damaging	0,03	deleterious	4,43	24,2	0,29	0,55	neutral	0,37	disease	0,9	disease	0,65	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,24	0,71	0,9	2,53	6,7	P	0,56	P	0,87	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6568	6568	C	A	MI.3293	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	665	222	P	H	cCc/cAc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,7	deleterious	-3,45	deleterious	-7,69	high_impact	4,89	neutral	0,69	damaging	0,04	deleterious	4,04	23,7	0,22	0,55	disease	0,74	disease	0,89	disease	0,71	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,42	0,68	0,9	2,53	6,7	P	0,66	P	0,81	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6568	6568	C	G	MI.3294	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	665	222	P	R	cCc/cGc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,81	deleterious	-7,69	high_impact	5,25	neutral	0,67	damaging	0,04	deleterious	3,64	23,2	0,26	0,55	disease	0,64	disease	0,92	disease	0,75	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,75	0,7	0,9	2,53	6,7	P	0,66	P	0,9	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6570	6570	G	A	MI.3295	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	667	223	A	T	Gcc/Acc	-10,51	0	0	benign	0	neutral	0,05	neutral	2,84	neutral	-1,12	neutral	-2,33	low_impact	1,64	damaging	0,55	neutral	0,5	neutral	1,2	11,74	0,39	0,55	neutral	0,38	disease	0,79	neutral	0,25	neutral	0,46	1	neutral	0,95	deleterious	0,53	neutral	-6	neutral	0,22	high_impact	2,07	medium_impact	-0,52	medium_impact	0,42	0,74	0,9	11,89	33,63	N	0,48	N	0,62	polymorphism	0,96	0,08	rs386828988	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6570	6570	G	T	MI.3296	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	667	223	A	S	Gcc/Tcc	-10,51	0	0	benign	0,07	neutral	0,48	neutral	2,92	neutral	-0,9	neutral	-1,36	neutral_impact	0,24	damaging	0,57	neutral	0,63	deleterious	0,33	5,97	0,4	0,55	neutral	0,37	neutral	0,43	neutral	0,18	neutral	0,45	1	neutral	0,46	deleterious	0,71	neutral	-6	neutral	0,21	medium_impact	0,3	medium_impact	0,17	medium_impact	-0,88	0,76	0,9	11,89	33,63	N	0,48	N	0,3	polymorphism	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6570	6570	G	C	MI.3297	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	667	223	A	P	Gcc/Ccc	-10,51	0	0	benign	0,3	deleterious	0	neutral	2,79	deleterious	-3,15	deleterious	-3,52	high_impact	4,08	neutral	0,61	neutral	0,38	deleterious	2,03	16,42	0,17	0,55	disease	0,73	disease	0,91	neutral	0,47	disease	0,72	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,65	medium_impact	-0,41	low_impact	-1,48	high_impact	2,67	0,72	0,9	11,89	33,63	N	0,4	N	0,73	polymorphism	0,87	0,18	rs386828988	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6571	6571	C	T	MI.3298	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	668	223	A	V	gCc/gTc	4,29	1	0	benign	0	neutral	0,06	neutral	2,87	neutral	-1,52	deleterious	-2,86	medium_impact	2,27	damaging	0,58	neutral	0,5	deleterious	2,54	19,73	0,32	0,55	neutral	0,42	disease	0,79	neutral	0,26	neutral	0,49	0	neutral	0,94	deleterious	0,53	neutral	-3	neutral	0,22	high_impact	2,07	medium_impact	-0,47	medium_impact	1	0,72	0,9	11,89	33,63	P	0,53	P	0,17	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6571	6571	C	A	MI.3299	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	668	223	A	D	gCc/gAc	4,29	1	0	benign	0,24	deleterious	0	neutral	2,8	neutral	-1,36	deleterious	-3,98	medium_impact	2,84	neutral	0,63	neutral	0,43	deleterious	2,63	20,4	0,24	0,55	disease	0,6	disease	0,89	disease	0,56	disease	0,63	3	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,54	medium_impact	-0,29	low_impact	-1,48	medium_impact	1,52	0,61	0,9	11,89	33,63	N	0,47	N	0,93	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8540	8540	T	A	MI.33	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	14	5	L	Q	cTg/cAg	-1,95	0	0	probably_damaging	0,99	deleterious	0	neutral	4,11	deleterious	-3,79	deleterious	-4,7	medium_impact	2,93	neutral	0,79	neutral	0,44	deleterious	3,94	23,5	0,25	0,65	disease	0,87	disease	0,59	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-2,65	low_impact	-1,4	medium_impact	1,41	0,66	0,9	50,44	8,42	N	0,31	N	0,98	polymorphism	0,57	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8680	8680	C	A	MI.330	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	154	52	L	M	Cta/Ata	-1,03	0	0	possibly_damaging	0,85	neutral	0,27	neutral	4,32	neutral	-1,75	neutral	-0,73	neutral_impact	0,64	neutral	0,94	neutral	0,74	deleterious	2,33	18,36	0,38	0,65	disease	0,58	neutral	0,21	neutral	0,17	neutral	0,46	1	neutral	0,89	neutral	0,21	neutral	-3	deleterious	0,66	low_impact	-1,47	medium_impact	0,05	medium_impact	-0,55	0,7	0,9	12,83	8,79	N	0,52	P	0,69	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6571	6571	C	G	MI.3300	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	668	223	A	G	gCc/gGc	4,29	1	0	benign	0,04	deleterious	0,03	neutral	2,83	neutral	-1,91	deleterious	-2,67	medium_impact	3,04	neutral	0,63	neutral	0,61	deleterious	2,06	16,62	0,22	0,55	disease	0,55	disease	0,72	neutral	0,47	neutral	0,48	0	neutral	0,97	deleterious	0,5	deleterious	1	neutral	0,24	medium_impact	0,54	medium_impact	-0,65	medium_impact	1,71	0,65	0,9	11,89	33,63	P	0,49	N	0,56	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6573	6573	G	T	MI.3301	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	670	224	G	W	Gga/Tga	-9,59	0	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-4,91	deleterious	-6,95	high_impact	5,2	neutral	0,62	damaging	0,08	deleterious	4,45	24,2	0,16	0,55	disease	0,86	disease	0,91	disease	0,76	disease	0,8	6	deleterious	1	deleterious	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,7	0,29	0,9	2,34	6,67	P	0,57	P	0,83	disease_causing	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6573	6573	G	C	MI.3302	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	670	224	G	R	Gga/Cga	-9,59	0	0	probably_damaging	1	deleterious	0,01	neutral	2,67	neutral	-2,89	deleterious	-6,92	high_impact	5,2	neutral	0,61	damaging	0,07	deleterious	3,99	23,6	0,15	0,55	neutral	0,27	disease	0,93	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,58	medium_impact	-0,92	high_impact	3,7	0,61	0,9	2,34	6,67	P	0,55	P	0,95	disease_causing	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6574	6574	G	C	MI.3303	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	671	224	G	A	gGa/gCa	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-2,14	deleterious	-5,19	high_impact	4	neutral	0,79	damaging	0,12	deleterious	3,15	22,6	0,22	0,55	neutral	0,29	disease	0,78	disease	0,65	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,72	low_impact	-3,58	low_impact	-1,48	high_impact	2,59	0,33	0,9	2,34	6,67	N	0,44	N	0,64	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6574	6574	G	T	MI.3304	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	671	224	G	V	gGa/gTa	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-2,03	deleterious	-7,8	high_impact	4,86	damaging	0,5	damaging	0,1	deleterious	3,85	23,4	0,16	0,55	neutral	0,49	disease	0,91	disease	0,73	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,39	0,44	0,9	2,34	6,67	P	0,65	P	0,93	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6574	6574	G	A	MI.3305	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	671	224	G	E	gGa/gAa	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-2,82	deleterious	-6,93	high_impact	4,5	damaging	0,58	damaging	0,08	deleterious	3,91	23,5	0,19	0,55	neutral	0,16	disease	0,9	disease	0,76	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,35	0,9	2,34	6,67	P	0,52	P	0,93	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6576	6576	G	T	MI.3306	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	673	225	G	W	Gga/Tga	-0,8	0,01	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-6,89	deleterious	-6,94	high_impact	5,29	neutral	0,62	damaging	0,09	deleterious	4,53	24,3	0,15	0,55	disease	0,94	disease	0,91	disease	0,78	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,32	0,9	2,73	6,67	P	0,6	P	0,83	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6576	6576	G	C	MI.3307	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	673	225	G	R	Gga/Cga	-0,8	0,01	0	probably_damaging	1	deleterious	0	neutral	2,58	neutral	-2,86	deleterious	-6,93	high_impact	5,29	neutral	0,62	damaging	0,07	deleterious	4,02	23,6	0,16	0,55	disease	0,66	disease	0,93	disease	0,78	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,64	0,9	2,73	6,67	P	0,65	P	0,95	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6577	6577	G	C	MI.3308	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	674	225	G	A	gGa/gCa	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,61	neutral	-2,69	deleterious	-5,18	high_impact	4	neutral	0,77	damaging	0,13	deleterious	3,16	22,6	0,16	0,55	disease	0,51	disease	0,78	disease	0,71	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,59	0,41	0,9	2,73	6,67	N	0,48	N	0,64	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6577	6577	G	A	MI.3309	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	674	225	G	E	gGa/gAa	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,61	neutral	-2,23	deleterious	-6,93	high_impact	5,29	damaging	0,58	damaging	0,09	deleterious	3,92	23,5	0,18	0,55	neutral	0,4	disease	0,9	disease	0,77	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,41	0,9	2,73	6,67	P	0,68	P	0,93	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8681	8681	T	C	MI.331	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	155	52	L	P	cTa/cCa	-1,95	0	0	possibly_damaging	0,8	neutral	0,29	neutral	4,31	neutral	-2,34	deleterious	-3,93	medium_impact	2,08	neutral	0,78	neutral	0,3	deleterious	2,43	18,98	0,17	0,65	disease	0,69	disease	0,78	disease	0,53	disease	0,72	4	neutral	0,84	neutral	0,25	NA	0	deleterious	0,78	low_impact	-1,33	medium_impact	0,07	medium_impact	0,69	0,51	0,9	12,83	8,79	N	0,25	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6577	6577	G	T	MI.3310	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	674	225	G	V	gGa/gTa	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-3,7	deleterious	-7,79	high_impact	4,94	damaging	0,51	damaging	0,1	deleterious	3,81	23,4	0,15	0,55	disease	0,71	disease	0,91	disease	0,69	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,46	0,35	0,9	2,73	6,67	P	0,64	P	0,93	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6579	6579	G	T	MI.3311	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	676	226	G	W	Gga/Tga	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-6,1	deleterious	-6,95	high_impact	4,96	neutral	0,64	damaging	0,09	deleterious	4,53	24,3	0,18	0,55	disease	0,97	disease	0,91	disease	0,72	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,26	0,9	2,53	7,28	P	0,56	P	0,83	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6579	6579	G	C	MI.3312	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	676	226	G	R	Gga/Cga	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-4,04	deleterious	-6,95	high_impact	5,31	neutral	0,63	damaging	0,07	deleterious	4,02	23,6	0,15	0,55	disease	0,77	disease	0,93	disease	0,81	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,61	0,9	2,53	7,28	P	0,64	P	0,95	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6580	6580	G	C	MI.3313	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	677	226	G	A	gGa/gCa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,56	neutral	-2,85	deleterious	-5,21	high_impact	4,96	neutral	0,62	damaging	0,15	deleterious	3,16	22,6	0,18	0,55	disease	0,68	disease	0,76	disease	0,71	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,44	0,9	2,53	7,28	P	0,72	P	0,64	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6580	6580	G	T	MI.3314	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	677	226	G	V	gGa/gTa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,52	neutral	-1,34	deleterious	-7,82	high_impact	5,31	neutral	0,61	damaging	0,09	deleterious	3,81	23,4	0,16	0,55	disease	0,78	disease	0,91	disease	0,73	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,39	0,9	2,53	7,28	P	0,7	P	0,93	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6580	6580	G	A	MI.3315	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	677	226	G	E	gGa/gAa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-3,9	deleterious	-6,95	high_impact	5,31	damaging	0,59	damaging	0,09	deleterious	3,9	23,5	0,15	0,55	neutral	0,35	disease	0,88	disease	0,8	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,44	0,9	2,53	7,28	P	0,68	P	0,93	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6582	6582	G	C	MI.3316	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	679	227	D	H	Gac/Cac	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-3,4	deleterious	-6,04	high_impact	4,89	damaging	0,52	damaging	0,1	deleterious	3,7	23,3	0,32	0,55	disease	0,71	disease	0,91	disease	0,73	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,42	0,5	0,9	2,53	7,06	P	0,6	P	0,97	disease_causing	0,99	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6582	6582	G	A	MI.3317	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	679	227	D	N	Gac/Aac	-1,95	0	0	probably_damaging	1	neutral	0,11	neutral	2,74	neutral	-1,03	deleterious	-4,31	medium_impact	3,5	damaging	0,53	damaging	0,1	deleterious	4,25	23,9	0,46	0,55	neutral	0,24	disease	0,89	disease	0,55	disease	0,64	3	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,77	low_impact	-3,58	medium_impact	-0,31	high_impact	2,13	0,71	0,9	2,53	7,06	N	0,33	N	0,89	disease_causing	0,95	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6582	6582	G	T	MI.3318	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	679	227	D	Y	Gac/Tac	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-5,32	deleterious	-7,77	high_impact	5,24	neutral	0,62	damaging	0,09	deleterious	3,97	23,6	0,22	0,55	disease	0,79	disease	0,96	disease	0,73	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,33	0,9	2,53	7,06	P	0,53	P	0,94	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6583	6583	A	G	MI.3319	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	680	227	D	G	gAc/gGc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-3	deleterious	-6,04	high_impact	4,54	damaging	0,6	damaging	0,12	deleterious	3,97	23,6	0,21	0,55	disease	0,65	disease	0,88	disease	0,7	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,09	0,29	0,9	2,53	7,06	P	0,54	P	0,85	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8681	8681	T	G	MI.332	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	155	52	L	R	cTa/cGa	-1,95	0	0	benign	0,02	neutral	0,56	neutral	4,35	neutral	-0,8	neutral	-2,09	neutral_impact	0,16	neutral	0,82	neutral	0,65	deleterious	-0,02	2,37	0,25	0,65	disease	0,75	neutral	0,46	neutral	0,32	disease	0,62	2	neutral	0,41	deleterious	0,77	neutral	-6	neutral	0,28	medium_impact	0,85	medium_impact	0,35	medium_impact	-0,96	0,63	0,9	12,83	8,79	N	0,22	N	0,98	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6583	6583	A	T	MI.3320	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	680	227	D	V	gAc/gTc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,47	deleterious	-5,09	deleterious	-7,77	high_impact	4,89	damaging	0,49	damaging	0,12	deleterious	3,73	23,3	0,22	0,55	disease	0,54	disease	0,94	disease	0,7	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,42	0,21	0,9	2,53	7,06	P	0,58	P	0,93	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6583	6583	A	C	MI.3321	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	680	227	D	A	gAc/gCc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-3,69	deleterious	-6,89	high_impact	4,89	neutral	0,72	damaging	0,13	deleterious	3,63	23,2	0,22	0,55	neutral	0,41	disease	0,89	disease	0,7	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,42	0,4	0,9	2,53	7,06	P	0,64	P	0,85	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6584	6584	C	G	MI.3322	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	681	227	D	E	gaC/gaG	6,84	1	0	probably_damaging	0,98	deleterious	0,03	neutral	2,52	deleterious	-3,19	deleterious	-3,45	high_impact	5,24	neutral	0,6	damaging	0,11	deleterious	3,9	23,5	0,4	0,55	neutral	0,43	disease	0,84	disease	0,56	disease	0,68	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,78	low_impact	-2,35	medium_impact	-0,65	high_impact	3,74	0,54	0,9	2,53	7,06	P	0,66	P	0,65	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6584	6584	C	A	MI.3323	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	681	227	D	E	gaC/gaA	6,84	1	0	probably_damaging	0,98	deleterious	0,03	neutral	2,52	deleterious	-3,19	deleterious	-3,45	high_impact	5,24	neutral	0,6	damaging	0,11	deleterious	4,21	23,9	0,4	0,55	neutral	0,43	disease	0,84	disease	0,56	disease	0,68	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,78	low_impact	-2,35	medium_impact	-0,65	high_impact	3,74	0,54	0,9	2,53	7,06	P	0,67	P	0,65	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6585	6585	C	T	MI.3324	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	682	228	P	S	Ccc/Tcc	-2,65	0	0	probably_damaging	1	deleterious	0	neutral	2,68	neutral	-2,75	deleterious	-6,93	high_impact	4,26	damaging	0,57	damaging	0,11	deleterious	3,89	23,5	0,28	0,55	disease	0,72	disease	0,84	disease	0,62	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,83	0,26	0,9	2,73	6,69	N	0,32	N	0,85	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6585	6585	C	A	MI.3325	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	682	228	P	T	Ccc/Acc	-2,65	0	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-2,87	deleterious	-6,93	high_impact	4,34	neutral	0,63	damaging	0,07	deleterious	3,85	23,4	0,23	0,55	disease	0,64	disease	0,86	disease	0,62	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,91	0,63	0,9	2,73	6,69	N	0,33	N	0,8	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6585	6585	C	G	MI.3326	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	682	228	P	A	Ccc/Gcc	-2,65	0	0	probably_damaging	1	deleterious	0	neutral	2,85	neutral	-1,54	deleterious	-6,93	medium_impact	3,42	neutral	0,68	damaging	0,11	deleterious	3,11	22,5	0,21	0,55	disease	0,68	disease	0,78	disease	0,53	disease	0,66	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,06	0,66	0,9	2,73	6,69	N	0,27	N	0,76	disease_causing	0,99	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6586	6586	C	T	MI.3327	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	683	228	P	L	cCc/cTc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-2,64	deleterious	-8,67	high_impact	3,65	damaging	0,5	damaging	0,1	deleterious	4,44	24,2	0,25	0,55	disease	0,75	disease	0,9	disease	0,6	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,27	0,66	0,9	2,73	6,69	N	0,46	N	0,87	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6586	6586	C	A	MI.3328	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	683	228	P	H	cCc/cAc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,65	deleterious	-4,6	deleterious	-7,8	high_impact	5,24	neutral	0,63	damaging	0,06	deleterious	4,08	23,7	0,16	0,55	disease	0,94	disease	0,9	disease	0,73	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,51	0,9	2,73	6,69	P	0,63	P	0,81	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6586	6586	C	G	MI.3329	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	683	228	P	R	cCc/cGc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-3,66	deleterious	-7,8	high_impact	5,24	damaging	0,6	damaging	0,05	deleterious	3,64	23,2	0,2	0,55	disease	0,87	disease	0,94	disease	0,75	disease	0,83	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,44	0,9	2,73	6,69	P	0,62	P	0,9	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8681	8681	T	A	MI.333	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	155	52	L	Q	cTa/cAa	-1,95	0	0	possibly_damaging	0,52	neutral	0,48	neutral	4,39	neutral	-0,07	deleterious	-2,6	low_impact	1,01	neutral	0,89	neutral	0,51	neutral	0,99	10,58	0,24	0,65	disease	0,72	neutral	0,46	neutral	0,19	disease	0,61	2	neutral	0,53	deleterious	0,48	neutral	-3	deleterious	0,63	medium_impact	-0,79	medium_impact	0,27	medium_impact	-0,23	0,58	0,9	12,83	8,79	N	0,36	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6588	6588	A	T	MI.3330	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	685	229	I	F	Att/Ttt	-12,83	0	0	possibly_damaging	0,55	deleterious	0	neutral	2,68	neutral	-2,58	deleterious	-3,44	high_impact	4,39	damaging	0,56	damaging	0,11	deleterious	4,04	23,7	0,21	0,55	disease	0,73	disease	0,85	neutral	0,44	disease	0,7	4	deleterious	1	neutral	0,23	deleterious	5	deleterious	0,62	medium_impact	-0,84	low_impact	-1,48	high_impact	2,95	0,75	0,9	6,63	9,18	N	0,37	N	0,85	disease_causing	0,54	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6588	6588	A	G	MI.3331	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	685	229	I	V	Att/Gtt	-12,83	0	0	benign	0	neutral	0,28	neutral	2,92	neutral	-0,24	neutral	-0,64	low_impact	0,98	neutral	0,67	neutral	0,87	deleterious	1,8	15	0,43	0,55	neutral	0,16	neutral	0,24	neutral	0,21	neutral	0,38	2	neutral	0,72	deleterious	0,64	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	-0,04	medium_impact	-0,19	0,64	0,9	6,63	9,18	N	0,53	P	0,23	polymorphism	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6588	6588	A	C	MI.3332	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	685	229	I	L	Att/Ctt	-12,83	0	0	benign	0,07	neutral	0,19	neutral	3	neutral	0,7	neutral	-1,72	medium_impact	2,96	neutral	0,63	damaging	0,12	deleterious	3,85	23,4	0,29	0,55	neutral	0,24	disease	0,68	neutral	0,24	neutral	0,44	1	neutral	0,79	deleterious	0,56	neutral	-3	neutral	0,16	medium_impact	0,3	medium_impact	-0,16	medium_impact	1,63	0,69	0,9	6,63	9,18	N	0,39	N	0,61	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6589	6589	T	C	MI.3333	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	686	229	I	T	aTt/aCt	2,67	0,98	0	possibly_damaging	0,9	deleterious	0	neutral	2,76	neutral	-2,19	deleterious	-4,08	high_impact	4,25	damaging	0,6	damaging	0,15	deleterious	3,38	23	0,24	0,55	disease	0,74	disease	0,79	disease	0,56	disease	0,66	3	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,52	low_impact	-1,65	low_impact	-1,48	high_impact	2,83	0,44	0,9	6,63	9,18	P	0,49	N	0,76	polymorphism	0,98	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6589	6589	T	A	MI.3334	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	686	229	I	N	aTt/aAt	2,67	0,98	0	probably_damaging	0,99	deleterious	0	neutral	2,66	deleterious	-3,76	deleterious	-5,93	high_impact	4,95	neutral	0,64	damaging	0,15	deleterious	4,43	24,2	0,17	0,55	disease	0,91	disease	0,91	disease	0,57	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	3,47	0,57	0,9	6,63	9,18	P	0,68	P	0,94	polymorphism	0,95	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6589	6589	T	G	MI.3335	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	686	229	I	S	aTt/aGt	2,67	0,98	0	probably_damaging	0,97	deleterious	0	neutral	2,69	neutral	-2,37	deleterious	-5,05	high_impact	4,95	neutral	0,65	damaging	0,17	deleterious	4,36	24,1	0,15	0,55	disease	0,84	disease	0,85	disease	0,57	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,69	low_impact	-2,18	low_impact	-1,48	high_impact	3,47	0,5	0,9	6,63	9,18	P	0,68	P	0,62	polymorphism	0,94	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6590	6590	T	G	MI.3336	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	687	229	I	M	atT/atG	7,53	1	0	possibly_damaging	0,78	deleterious	0	neutral	2,72	neutral	-1,35	neutral	-2,47	high_impact	3,53	neutral	0,65	damaging	0,15	deleterious	3,44	23	0,28	0,55	neutral	0,38	disease	0,66	disease	0,56	disease	0,63	3	deleterious	1	neutral	0,11	deleterious	5	neutral	0,34	low_impact	-1,27	low_impact	-1,48	high_impact	2,16	0,77	0,9	6,63	9,18	P	0,51	P	0,76	polymorphism	0,96	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6590	6590	T	A	MI.3337	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	687	229	I	M	atT/atA	7,53	1	0	possibly_damaging	0,78	deleterious	0	neutral	2,72	neutral	-1,35	neutral	-2,47	high_impact	3,53	neutral	0,65	damaging	0,15	deleterious	3,79	23,4	0,28	0,55	neutral	0,38	disease	0,66	disease	0,56	disease	0,63	3	deleterious	1	neutral	0,11	deleterious	5	neutral	0,34	low_impact	-1,27	low_impact	-1,48	high_impact	2,16	0,77	0,9	6,63	9,18	P	0,52	P	0,76	polymorphism	0,96	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6591	6591	C	G	MI.3338	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	688	230	L	V	Cta/Gta	-6,58	0	0	probably_damaging	0,99	deleterious	0,01	neutral	2,61	neutral	-2,7	deleterious	-2,6	high_impact	4,19	damaging	0,5	damaging	0,12	deleterious	3,44	23	0,2	0,55	neutral	0,43	disease	0,75	neutral	0,47	disease	0,56	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-2,64	medium_impact	-0,92	high_impact	2,77	0,6	0,9	2,53	6,67	N	0,33	N	0,66	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6591	6591	C	A	MI.3339	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	688	230	L	M	Cta/Ata	-6,58	0	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-3,24	neutral	-1,73	high_impact	4	neutral	0,61	damaging	0,17	deleterious	3,75	23,3	0,16	0,55	disease	0,67	disease	0,64	neutral	0,43	neutral	0,49	0	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	2,59	0,65	0,9	2,53	6,67	N	0,37	N	0,59	polymorphism	1	0,08	rs28483589	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8683	8683	A	T	MI.334	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	157	53	T	S	Acc/Tcc	-12,37	0	0	benign	0,14	neutral	0,05	neutral	4,31	neutral	-1,75	neutral	-1,38	low_impact	0,88	neutral	0,84	neutral	0,65	deleterious	0,27	5,43	0,39	0,65	disease	0,57	neutral	0,23	neutral	0,43	disease	0,54	1	neutral	0,94	neutral	0,46	neutral	-6	neutral	0,26	medium_impact	-0,01	medium_impact	-0,43	medium_impact	-0,34	0,69	0,9	11,95	17,19	N	0,45	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6592	6592	T	G	MI.3340	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	689	230	L	R	cTa/cGa	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-5,3	deleterious	-5,2	high_impact	5,29	damaging	0,54	damaging	0,11	deleterious	4,15	23,8	0,1	0,55	disease	0,79	disease	0,93	disease	0,72	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,37	0,9	2,53	6,67	P	0,59	P	0,9	polymorphism	0,88	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6592	6592	T	C	MI.3341	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	689	230	L	P	cTa/cCa	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,47	deleterious	-5,94	deleterious	-6,07	high_impact	5,29	damaging	0,42	damaging	0,17	deleterious	3,87	23,5	0,11	0,55	disease	0,85	disease	0,85	disease	0,72	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,48	0,9	2,53	6,67	P	0,62	P	0,83	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6592	6592	T	A	MI.3342	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	689	230	L	Q	cTa/cAa	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,47	deleterious	-5,42	deleterious	-5,2	high_impact	5,29	damaging	0,54	damaging	0,12	deleterious	4,06	23,7	0,11	0,55	disease	0,81	disease	0,84	disease	0,59	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,61	0,9	2,53	6,67	P	0,6	P	0,82	polymorphism	0,9	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6594	6594	T	A	MI.3343	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	691	231	Y	N	Tac/Aac	-7,51	0	0	probably_damaging	1	deleterious	0	neutral	2,79	neutral	-2,4	deleterious	-6,97	high_impact	4,87	damaging	0,6	damaging	0,06	deleterious	4,02	23,6	0,13	0,55	disease	0,7	disease	0,88	disease	0,59	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,4	0,38	0,9	3,7	6,65	P	0,58	P	0,94	polymorphism	0,89	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6594	6594	T	G	MI.3344	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	691	231	Y	D	Tac/Gac	-7,51	0	0	probably_damaging	1	deleterious	0	neutral	2,83	deleterious	-3,83	deleterious	-7,59	high_impact	4,87	damaging	0,57	damaging	0,05	deleterious	3,94	23,5	0,1	0,55	disease	0,77	disease	0,87	disease	0,69	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,4	0,41	0,9	3,7	6,65	P	0,57	P	0,98	polymorphism	0,92	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6594	6594	T	C	MI.3345	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	691	231	Y	H	Tac/Cac	-7,51	0	0	probably_damaging	1	deleterious	0	neutral	2,77	deleterious	-3,43	deleterious	-4,05	high_impact	4,87	neutral	0,62	damaging	0,05	deleterious	3,57	23,2	0,13	0,55	disease	0,74	disease	0,82	disease	0,7	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,4	0,45	0,9	3,7	6,65	P	0,64	P	0,61	polymorphism	0,99	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6595	6595	A	T	MI.3346	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	692	231	Y	F	tAc/tTc	7,53	1	0	probably_damaging	1	neutral	0,43	neutral	2,89	neutral	-0,39	neutral	-1,65	neutral_impact	0,74	damaging	0,5	damaging	0,1	deleterious	2,19	17,47	0,21	0,55	neutral	0,44	neutral	0,41	neutral	0,26	neutral	0,41	2	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,73	low_impact	-3,58	medium_impact	0,13	medium_impact	-0,42	0,6	0,9	3,7	6,65	P	0,58	P	0,5	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6595	6595	A	G	MI.3347	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	692	231	Y	C	tAc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,76	deleterious	-3,74	deleterious	-6,73	high_impact	4,87	damaging	0,58	damaging	0,05	deleterious	3,48	23,1	0,13	0,55	disease	0,76	disease	0,89	disease	0,64	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,4	0,33	0,9	3,7	6,65	P	0,64	P	0,89	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6595	6595	A	C	MI.3348	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	692	231	Y	S	tAc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,81	neutral	-1,27	deleterious	-6,71	high_impact	4,07	neutral	0,6	damaging	0,07	deleterious	3,69	23,3	0,11	0,55	neutral	0,43	disease	0,81	disease	0,59	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,66	0,46	0,9	3,7	6,65	N	0,44	N	0,9	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6597	6597	C	G	MI.3349	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	694	232	Q	E	Caa/Gaa	-4,5	0	0	probably_damaging	0,98	deleterious	0,01	neutral	2,79	neutral	-1,04	deleterious	-2,55	high_impact	3,89	neutral	0,66	damaging	0,14	deleterious	3,08	22,5	0,34	0,55	neutral	0,37	disease	0,77	disease	0,61	disease	0,62	2	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,78	low_impact	-2,35	medium_impact	-0,92	high_impact	2,49	0,71	0,9	2,53	6,9	N	0,32	N	0,72	polymorphism	0,98	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8683	8683	A	C	MI.335	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	157	53	T	P	Acc/Ccc	-12,37	0	0	possibly_damaging	0,48	deleterious	0,02	neutral	4,28	deleterious	-3,23	deleterious	-3,03	medium_impact	2,12	neutral	0,78	neutral	0,36	deleterious	3,03	22,3	0,17	0,65	disease	0,84	disease	0,69	disease	0,75	disease	0,82	6	neutral	0,98	neutral	0,27	deleterious	4	deleterious	0,67	medium_impact	-0,72	medium_impact	-0,66	medium_impact	0,72	0,61	0,9	11,95	17,19	N	0,3	N	0,82	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6597	6597	C	A	MI.3350	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	694	232	Q	K	Caa/Aaa	-4,5	0	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-1,13	deleterious	-3,4	high_impact	4,92	neutral	0,64	damaging	0,12	deleterious	4,11	23,7	0,31	0,55	neutral	0,44	disease	0,89	disease	0,7	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,57	0,9	2,53	6,9	P	0,6	P	0,83	polymorphism	0,97	0,27	.	.	.	.	.	.	.	.	.	C6597A	MELAS-like syndrome	-	+	Reported	1
chrM	6598	6598	A	G	MI.3351	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	695	232	Q	R	cAa/cGa	7,3	1	0	probably_damaging	1	deleterious	0,01	neutral	2,69	neutral	-1,88	deleterious	-3,4	high_impact	5,28	neutral	0,68	damaging	0,12	deleterious	3,57	23,1	0,35	0,55	neutral	0,41	disease	0,91	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,58	medium_impact	-0,92	high_impact	3,78	0,52	0,9	2,53	6,9	P	0,7	P	0,76	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6598	6598	A	C	MI.3352	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	695	232	Q	P	cAa/cCa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-4,52	deleterious	-5,12	high_impact	5,28	neutral	0,61	damaging	0,14	deleterious	3,36	22,9	0,15	0,55	disease	0,77	disease	0,89	disease	0,76	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,61	0,9	2,53	6,9	P	0,71	P	0,84	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6598	6598	A	T	MI.3353	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	695	232	Q	L	cAa/cTa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-3,43	deleterious	-5,93	high_impact	4,92	neutral	0,67	damaging	0,13	deleterious	3,88	23,5	0,12	0,55	disease	0,69	disease	0,9	disease	0,6	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,33	0,9	2,53	6,9	P	0,69	P	0,71	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6599	6599	A	T	MI.3354	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	696	232	Q	H	caA/caT	6,84	1	0,01	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-5,45	deleterious	-4,25	high_impact	4,92	damaging	0,57	damaging	0,15	deleterious	3,69	23,3	0,3	0,55	disease	0,73	disease	0,85	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,72	0,9	2,53	6,9	P	0,7	P	0,7	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6599	6599	A	C	MI.3355	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	696	232	Q	H	caA/caC	6,84	1	0,01	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-5,45	deleterious	-4,25	high_impact	4,92	damaging	0,57	damaging	0,15	deleterious	3,5	23,1	0,3	0,55	disease	0,73	disease	0,85	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,72	0,9	2,53	6,9	P	0,7	P	0,7	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6600	6600	C	T	MI.3356	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	697	233	H	Y	Cac/Tac	1,05	1	0	probably_damaging	1	deleterious	0	neutral	2,79	deleterious	-3,98	deleterious	-5,15	high_impact	4,6	neutral	0,6	damaging	0,09	deleterious	3,71	23,3	0,2	0,55	disease	0,81	disease	0,9	disease	0,73	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,15	0,49	0,9	2,34	6,97	N	0,47	N	0,72	disease_causing	0,99	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6600	6600	C	G	MI.3357	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	697	233	H	D	Cac/Gac	1,05	1	0	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-3,02	deleterious	-7,72	high_impact	4,6	damaging	0,59	damaging	0,1	deleterious	3,86	23,5	0,16	0,55	disease	0,55	disease	0,85	disease	0,78	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,15	0,54	0,9	2,34	6,97	P	0,56	P	0,97	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6600	6600	C	A	MI.3358	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	697	233	H	N	Cac/Aac	1,05	1	0	probably_damaging	1	deleterious	0	neutral	2,8	neutral	-1,57	deleterious	-5,99	high_impact	4,75	damaging	0,52	damaging	0,12	deleterious	4,02	23,6	0,21	0,55	neutral	0,39	disease	0,88	disease	0,71	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,64	0,9	2,34	6,97	P	0,59	P	0,86	disease_causing	0,99	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6601	6601	A	C	MI.3359	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	698	233	H	P	cAc/cCc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-4,16	deleterious	-8,59	high_impact	5,29	damaging	0,53	damaging	0,11	deleterious	3,15	22,6	0,17	0,55	neutral	0,36	disease	0,89	disease	0,8	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,48	0,9	2,34	6,97	P	0,6	P	0,9	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8683	8683	A	G	MI.336	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	157	53	T	A	Acc/Gcc	-12,37	0	0	benign	0,01	neutral	0,2	neutral	4,34	neutral	-0,94	neutral	-1,36	neutral_impact	0,36	neutral	0,97	neutral	0,84	deleterious	0,32	5,87	0,49	0,65	neutral	0,5	neutral	0,19	neutral	0,45	neutral	0,26	5	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,14	medium_impact	1,14	medium_impact	-0,05	medium_impact	-0,79	0,39	0,9	11,95	17,19	N	0,43	N	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6601	6601	A	T	MI.3360	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	698	233	H	L	cAc/cTc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,81	neutral	-2,47	deleterious	-9,44	high_impact	4,49	neutral	0,63	damaging	0,09	deleterious	3,71	23,3	0,15	0,55	disease	0,68	disease	0,91	disease	0,71	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,05	0,42	0,9	2,34	6,97	P	0,57	P	0,92	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6601	6601	A	G	MI.3361	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	698	233	H	R	cAc/cGc	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,73	neutral	-2,88	deleterious	-6,86	high_impact	4,39	damaging	0,59	damaging	0,09	deleterious	2,91	21,9	0,23	0,55	disease	0,57	disease	0,89	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,95	0,56	0,9	2,34	6,97	N	0,47	N	0,85	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6602	6602	C	G	MI.3362	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	699	233	H	Q	caC/caG	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,63	deleterious	-6,85	high_impact	5,29	neutral	0,64	damaging	0,1	deleterious	3,64	23,2	0,23	0,55	neutral	0,48	disease	0,82	disease	0,66	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,58	0,9	2,34	6,97	P	0,67	P	0,83	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6602	6602	C	A	MI.3363	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	699	233	H	Q	caC/caA	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,63	deleterious	-6,85	high_impact	5,29	neutral	0,64	damaging	0,1	deleterious	3,98	23,6	0,23	0,55	neutral	0,48	disease	0,82	disease	0,66	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,58	0,9	2,34	6,97	P	0,67	P	0,83	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6603	6603	C	G	MI.3364	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	700	234	L	V	Cta/Gta	0,13	0,02	0	probably_damaging	0,98	deleterious	0	neutral	2,48	neutral	-2,96	deleterious	-2,59	high_impact	4,24	damaging	0,52	damaging	0,06	deleterious	3,43	23	0,34	0,55	disease	0,61	disease	0,76	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,35	low_impact	-1,48	high_impact	2,82	0,58	0,9	2,53	6,72	N	0,34	N	0,66	disease_causing	0,97	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6603	6603	C	A	MI.3365	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	700	234	L	M	Cta/Ata	0,13	0,02	0	probably_damaging	1	neutral	0,06	neutral	2,39	deleterious	-4,15	neutral	-1,72	high_impact	3,81	damaging	0,56	damaging	0,08	deleterious	3,96	23,6	0,25	0,55	disease	0,56	disease	0,65	disease	0,52	disease	0,56	1	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,74	low_impact	-3,58	medium_impact	-0,47	high_impact	2,42	0,59	0,9	2,53	6,72	N	0,36	N	0,59	disease_causing	0,97	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6604	6604	T	G	MI.3366	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	701	234	L	R	cTa/cGa	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,31	deleterious	-5,27	deleterious	-5,17	high_impact	5,28	damaging	0,51	damaging	0,04	deleterious	4,25	23,9	0,13	0,55	neutral	0,43	disease	0,92	disease	0,76	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,46	0,9	2,53	6,72	P	0,57	P	0,9	polymorphism	0,9	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6604	6604	T	C	MI.3367	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	701	234	L	P	cTa/cCa	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,31	deleterious	-6,01	deleterious	-6,04	high_impact	4,93	damaging	0,39	damaging	0,05	deleterious	3,96	23,6	0,12	0,55	disease	0,91	disease	0,84	disease	0,76	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,42	0,9	2,53	6,72	P	0,55	P	0,83	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6604	6604	T	A	MI.3368	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	701	234	L	Q	cTa/cAa	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,32	deleterious	-5,51	deleterious	-5,17	high_impact	4,93	damaging	0,54	damaging	0,05	deleterious	4,15	23,8	0,15	0,55	disease	0,88	disease	0,85	disease	0,65	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,68	0,9	2,53	6,72	P	0,56	P	0,82	polymorphism	0,92	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6606	6606	T	C	MI.3369	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	703	235	F	L	Ttc/Ctc	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-3,82	deleterious	-5,03	high_impact	4,76	neutral	0,6	neutral	0,68	deleterious	4,08	23,7	0,37	0,55	neutral	0,33	disease	0,84	disease	0,74	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,81	0,9	2,34	6,8	P	0,64	P	0,83	disease_causing	0,99	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8684	8684	C	T	MI.337	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	158	53	T	I	aCc/aTc	0,13	0	0,04	benign	0,01	neutral	0,4	neutral	4,53	neutral	1,16	neutral	-0,23	neutral_impact	-1,06	neutral	0,97	neutral	0,97	deleterious	0,47	7,17	0,28	0,65	neutral	0,29	neutral	0,23	neutral	0,43	neutral	0,41	2	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	1,14	medium_impact	0,19	low_impact	-2,01	0,65	0,9	11,95	17,19	N	0,32	N	0,06	polymorphism	1	0,01	rs201336180	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6606	6606	T	A	MI.3370	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	703	235	F	I	Ttc/Atc	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-4,02	deleterious	-5,03	high_impact	4,96	neutral	0,75	neutral	0,68	deleterious	4,45	24,2	0,2	0,55	disease	0,72	disease	0,87	disease	0,79	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,66	0,9	2,34	6,8	P	0,7	P	0,88	disease_causing	0,99	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6606	6606	T	G	MI.3371	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	703	235	F	V	Ttc/Gtc	-1,95	0	0	probably_damaging	1	deleterious	0,02	neutral	2,45	deleterious	-4,93	deleterious	-5,87	high_impact	5,31	neutral	0,67	neutral	0,56	deleterious	4,1	23,7	0,26	0,55	disease	0,77	disease	0,91	disease	0,77	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-3,58	medium_impact	-0,75	high_impact	3,8	0,64	0,9	2,34	6,8	P	0,67	P	0,84	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6607	6607	T	G	MI.3372	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	704	235	F	C	tTc/tGc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,39	deleterious	-7,92	deleterious	-6,73	high_impact	5,31	neutral	0,72	neutral	0,56	deleterious	4,13	23,8	0,24	0,55	disease	0,96	disease	0,89	disease	0,8	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,36	0,9	2,34	6,8	P	0,62	P	0,91	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6607	6607	T	A	MI.3373	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	704	235	F	Y	tTc/tAc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-4,79	deleterious	-2,52	high_impact	4,96	neutral	0,62	neutral	0,53	deleterious	4,5	24,3	0,22	0,55	disease	0,71	disease	0,85	disease	0,76	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,71	0,9	2,34	6,8	P	0,75	P	0,59	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6607	6607	T	C	MI.3374	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	704	235	F	S	tTc/tCc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-6,68	deleterious	-6,7	high_impact	5,31	neutral	0,85	neutral	0,67	deleterious	4,36	24,1	0,23	0,55	disease	0,93	disease	0,86	disease	0,76	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,45	0,9	2,34	6,8	P	0,56	P	0,84	disease_causing	1	0,49	rs2853818	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6608	6608	C	G	MI.3375	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	705	235	F	L	ttC/ttG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-3,82	deleterious	-5,03	high_impact	4,76	neutral	0,6	neutral	0,68	deleterious	4,45	24,2	0,37	0,55	neutral	0,33	disease	0,84	disease	0,74	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,81	0,9	2,34	6,8	P	0,62	P	0,83	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6608	6608	C	A	MI.3376	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	705	235	F	L	ttC/ttA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-3,82	deleterious	-5,03	high_impact	4,76	neutral	0,6	neutral	0,68	deleterious	4,68	24,6	0,37	0,55	neutral	0,33	disease	0,84	disease	0,74	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,81	0,9	2,34	6,8	P	0,62	P	0,83	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6609	6609	T	C	MI.3377	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	706	236	W	R	Tga/Cga	-0,8	0,02	0	probably_damaging	1	deleterious	0	neutral	1,01	deleterious	-9,07	deleterious	-10,09	high_impact	4,61	neutral	0,63	damaging	0,04	deleterious	3,58	23,2	0,2	0,55	disease	0,84	disease	0,94	disease	0,81	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,16	0,25	0,9	2,14	6,63	N	0,46	N	0,98	disease_causing	0,97	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6609	6609	T	G	MI.3378	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	706	236	W	G	Tga/Gga	-0,8	0,02	0	probably_damaging	1	deleterious	0	neutral	1,02	deleterious	-8,48	deleterious	-9,37	high_impact	5,3	neutral	0,65	damaging	0,05	deleterious	3,92	23,5	0,18	0,55	disease	0,93	disease	0,87	disease	0,79	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,26	0,9	2,14	6,63	P	0,53	P	0,89	disease_causing	0,99	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6610	6610	G	C	MI.3379	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	707	236	W	S	tGa/tCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	1,03	deleterious	-7,3	deleterious	-10,08	high_impact	5,3	neutral	0,64	damaging	0,05	deleterious	4,12	23,8	0,18	0,55	disease	0,93	disease	0,91	disease	0,77	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,23	0,9	2,14	6,63	P	0,55	P	0,89	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8684	8684	C	A	MI.338	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	158	53	T	N	aCc/aAc	0,13	0	0,04	possibly_damaging	0,56	neutral	0,07	neutral	4,29	neutral	-2,97	neutral	-2,47	low_impact	1,77	neutral	0,81	neutral	0,55	deleterious	3,32	22,9	0,28	0,65	disease	0,81	neutral	0,44	disease	0,65	disease	0,69	4	neutral	0,93	neutral	0,26	neutral	-3	deleterious	0,61	medium_impact	-0,86	medium_impact	-0,34	medium_impact	0,42	0,74	0,9	11,95	17,19	N	0,33	N	0,64	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6610	6610	G	T	MI.3380	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	707	236	W	L	tGa/tTa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	1,03	deleterious	-7,66	deleterious	-9,37	high_impact	4,96	neutral	0,69	damaging	0,03	deleterious	4,31	24	0,16	0,55	disease	0,89	disease	0,89	disease	0,77	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,25	0,9	2,14	6,63	P	0,61	P	0,95	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6611	6611	A	T	MI.3381	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	708	236	W	C	tgA/tgT	9,15	1	0	probably_damaging	1	deleterious	0	neutral	1,01	deleterious	-9,9	deleterious	-9,39	high_impact	4,61	damaging	0,59	damaging	0,04	deleterious	4,14	23,8	0,21	0,55	disease	0,97	disease	0,91	disease	0,82	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,16	0,19	0,9	2,14	6,63	N	0,49	N	0,88	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6611	6611	A	C	MI.3382	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	708	236	W	C	tgA/tgC	9,15	1	0	probably_damaging	1	deleterious	0	neutral	1,01	deleterious	-9,9	deleterious	-9,39	high_impact	4,61	damaging	0,59	damaging	0,04	deleterious	4,06	23,7	0,21	0,55	disease	0,97	disease	0,91	disease	0,82	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,16	0,19	0,9	2,14	6,63	N	0,49	N	0,88	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6612	6612	T	C	MI.3383	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	709	237	F	L	Ttt/Ctt	5,68	1	0	probably_damaging	0,99	deleterious	0	neutral	2,72	neutral	-2	deleterious	-4,26	high_impact	4,61	neutral	0,81	damaging	0,06	deleterious	4,16	23,8	0,3	0,55	neutral	0,39	disease	0,84	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-2,64	low_impact	-1,48	high_impact	3,16	0,78	0,9	2,73	6,76	P	0,51	P	0,83	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6612	6612	T	A	MI.3384	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	709	237	F	I	Ttt/Att	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,74	neutral	-1,82	deleterious	-4,26	high_impact	4,41	neutral	0,73	damaging	0,08	deleterious	4,48	24,2	0,19	0,55	neutral	0,32	disease	0,87	disease	0,64	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,97	0,53	0,9	2,73	6,76	P	0,55	P	0,88	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6612	6612	T	G	MI.3385	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	709	237	F	V	Ttt/Gtt	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-2,52	deleterious	-4,97	high_impact	4,61	neutral	0,72	damaging	0,07	deleterious	4,18	23,8	0,23	0,55	neutral	0,4	disease	0,9	disease	0,72	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,16	0,55	0,9	2,73	6,76	P	0,55	P	0,84	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6613	6613	T	G	MI.3386	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	710	237	F	C	tTt/tGt	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-5,1	deleterious	-5,7	high_impact	5,3	neutral	0,73	damaging	0,05	deleterious	4,18	23,8	0,22	0,55	disease	0,89	disease	0,88	disease	0,71	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,26	0,9	2,73	6,76	P	0,68	P	0,91	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6613	6613	T	C	MI.3387	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	710	237	F	S	tTt/tCt	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,66	deleterious	-3,21	deleterious	-5,66	high_impact	4,95	neutral	0,75	damaging	0,08	deleterious	4,37	24,1	0,23	0,55	disease	0,84	disease	0,85	disease	0,7	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,47	0,34	0,9	2,73	6,76	P	0,71	P	0,84	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6613	6613	T	A	MI.3388	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	710	237	F	Y	tTt/tAt	5,68	1	0	probably_damaging	0,99	deleterious	0	neutral	2,71	neutral	-2,15	neutral	-2,13	high_impact	5,3	neutral	0,72	damaging	0,06	deleterious	4,53	24,3	0,21	0,55	disease	0,75	disease	0,84	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,64	low_impact	-1,48	high_impact	3,8	0,62	0,9	2,73	6,76	P	0,73	P	0,59	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6614	6614	T	A	MI.3389	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	711	237	F	L	ttT/ttA	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,72	neutral	-2	deleterious	-4,26	high_impact	4,61	neutral	0,81	damaging	0,06	deleterious	4,42	24,2	0,3	0,55	neutral	0,39	disease	0,84	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-2,64	low_impact	-1,48	high_impact	3,16	0,78	0,9	2,73	6,76	P	0,52	P	0,83	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8684	8684	C	G	MI.339	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	158	53	T	S	aCc/aGc	0,13	0	0,04	benign	0,14	neutral	0,05	neutral	4,31	neutral	-1,75	neutral	-1,38	low_impact	0,88	neutral	0,84	neutral	0,65	deleterious	0,46	7,14	0,39	0,65	disease	0,57	neutral	0,23	neutral	0,43	disease	0,54	1	neutral	0,94	neutral	0,46	neutral	-6	neutral	0,26	medium_impact	-0,01	medium_impact	-0,43	medium_impact	-0,34	0,69	0,9	11,95	17,19	N	0,45	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6614	6614	T	G	MI.3390	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	711	237	F	L	ttT/ttG	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,72	neutral	-2	deleterious	-4,26	high_impact	4,61	neutral	0,81	damaging	0,06	deleterious	4,22	23,9	0,3	0,55	neutral	0,39	disease	0,84	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-2,64	low_impact	-1,48	high_impact	3,16	0,78	0,9	2,73	6,76	N	0,49	N	0,83	disease_causing	1	0,18	rs28410416	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6615	6615	T	G	MI.3391	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	712	238	F	V	Ttc/Gtc	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-2,4	deleterious	-4,94	high_impact	5,28	neutral	0,73	damaging	0,07	deleterious	4,05	23,7	0,27	0,55	disease	0,87	disease	0,91	disease	0,72	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,49	0,9	1,75	7,02	P	0,68	P	0,84	disease_causing	0,99	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6615	6615	T	C	MI.3392	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	712	238	F	L	Ttc/Ctc	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,56	neutral	-1,64	deleterious	-4,22	high_impact	3,78	neutral	0,77	damaging	0,05	deleterious	4,01	23,6	0,29	0,55	disease	0,75	disease	0,86	disease	0,64	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,39	0,76	0,9	1,75	7,02	N	0,3	N	0,83	disease_causing	0,99	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6615	6615	T	A	MI.3393	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	712	238	F	I	Ttc/Atc	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,56	neutral	-2,52	deleterious	-4,23	high_impact	5,28	neutral	0,75	damaging	0,07	deleterious	4,35	24,1	0,22	0,55	disease	0,87	disease	0,89	disease	0,71	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,6	0,9	1,75	7,02	P	0,69	P	0,88	disease_causing	0,99	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6616	6616	T	G	MI.3394	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	713	238	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-5,02	deleterious	-5,66	high_impact	5,28	neutral	0,75	damaging	0,06	deleterious	4,06	23,7	0,24	0,55	disease	0,96	disease	0,88	disease	0,72	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,26	0,9	1,75	7,02	P	0,67	P	0,91	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6616	6616	T	C	MI.3395	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	713	238	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-3,49	deleterious	-5,64	high_impact	4,93	neutral	0,76	damaging	0,08	deleterious	4,24	23,9	0,24	0,55	disease	0,89	disease	0,85	disease	0,7	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,33	0,9	1,75	7,02	P	0,71	P	0,84	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6616	6616	T	A	MI.3396	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	713	238	F	Y	tTc/tAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,6	neutral	-2,36	neutral	-2,12	high_impact	3,58	neutral	0,74	damaging	0,07	deleterious	4,17	23,8	0,22	0,55	neutral	0,27	disease	0,86	disease	0,65	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,21	0,65	0,9	1,75	7,02	N	0,51	P	0,59	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6617	6617	C	G	MI.3397	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	714	238	F	L	ttC/ttG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,56	neutral	-1,64	deleterious	-4,22	high_impact	3,78	neutral	0,77	damaging	0,05	deleterious	4,36	24,1	0,29	0,55	disease	0,75	disease	0,86	disease	0,64	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,39	0,76	0,9	1,75	7,02	P	0,52	P	0,83	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6617	6617	C	A	MI.3398	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	714	238	F	L	ttC/ttA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,56	neutral	-1,64	deleterious	-4,22	high_impact	3,78	neutral	0,77	damaging	0,05	deleterious	4,63	24,5	0,29	0,55	disease	0,75	disease	0,86	disease	0,64	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,39	0,76	0,9	1,75	7,02	P	0,52	P	0,83	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6618	6618	G	C	MI.3399	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	715	239	G	R	Ggt/Cgt	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	2,29	deleterious	-5,15	deleterious	-5,63	high_impact	5,3	damaging	0,42	damaging	0,03	deleterious	3,97	23,6	0,14	0,55	disease	0,89	disease	0,93	disease	0,79	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,72	0,9	2,34	6,81	P	0,59	P	0,95	polymorphism	0,54	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8540	8540	T	G	MI.34	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	14	5	L	R	cTg/cGg	-1,95	0	0	probably_damaging	0,99	deleterious	0	neutral	4,11	deleterious	-3,77	deleterious	-4,69	medium_impact	2,93	neutral	0,76	neutral	0,36	deleterious	4,03	23,6	0,23	0,65	disease	0,86	disease	0,77	disease	0,79	disease	0,85	7	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,88	low_impact	-2,65	low_impact	-1,4	medium_impact	1,41	0,66	0,9	50,44	8,42	N	0,31	N	0,99	polymorphism	0,52	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8686	8686	T	C	MI.340	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	160	54	S	P	Tca/Cca	-5,89	0	0	benign	0,33	neutral	0,2	neutral	4,34	neutral	-2,16	neutral	-2,16	medium_impact	2,23	neutral	0,78	neutral	0,36	deleterious	2,14	17,11	0,23	0,65	disease	0,75	disease	0,78	disease	0,52	disease	0,72	4	neutral	0,76	neutral	0,44	neutral	-3	deleterious	0,59	medium_impact	-0,46	medium_impact	-0,05	medium_impact	0,81	0,49	0,9	28,32	24,19	N	0,25	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6618	6618	G	T	MI.3400	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	715	239	G	C	Ggt/Tgt	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	2,28	deleterious	-6,83	deleterious	-6,34	high_impact	5,3	damaging	0,37	damaging	0,03	deleterious	4,21	23,9	0,13	0,55	disease	0,89	disease	0,92	disease	0,69	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,56	0,9	2,34	6,81	P	0,49	N	0,98	disease_causing	0,63	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6618	6618	G	A	MI.3401	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	715	239	G	S	Ggt/Agt	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	2,37	deleterious	-3,23	deleterious	-4,2	high_impact	3,98	damaging	0,45	damaging	0,04	deleterious	4,2	23,9	0,2	0,55	neutral	0,31	disease	0,84	disease	0,66	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,58	0,68	0,9	2,34	6,81	N	0,37	N	0,73	polymorphism	0,71	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6619	6619	G	T	MI.3402	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	716	239	G	V	gGt/gTt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-4,8	deleterious	-6,32	high_impact	5,3	damaging	0,47	damaging	0,04	deleterious	3,8	23,4	0,13	0,55	disease	0,82	disease	0,92	disease	0,71	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,48	0,9	2,34	6,81	P	0,62	P	0,93	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6619	6619	G	C	MI.3403	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	716	239	G	A	gGt/gCt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,38	deleterious	-3,56	deleterious	-4,2	high_impact	5,3	damaging	0,56	damaging	0,05	deleterious	3,17	22,7	0,23	0,55	disease	0,59	disease	0,8	disease	0,6	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,73	0,9	2,34	6,81	P	0,67	P	0,64	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6619	6619	G	A	MI.3404	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	716	239	G	D	gGt/gAt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,28	deleterious	-5,18	deleterious	-4,92	high_impact	4,95	damaging	0,29	damaging	0,03	deleterious	3,76	23,3	0,13	0,55	disease	0,84	disease	0,91	disease	0,73	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,47	0,41	0,9	2,34	6,81	P	0,8	P	0,97	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6621	6621	C	A	MI.3405	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	718	240	H	N	Cac/Aac	-20	0	0	probably_damaging	1	deleterious	0	neutral	-1,22	deleterious	-12,3	deleterious	-4,88	high_impact	5,3	damaging	0,51	damaging	0,02	deleterious	3,9	23,5	0,34	0,55	disease	0,8	disease	0,87	disease	0,75	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,44	0,9	3,31	6,76	N	0,43	N	0,86	polymorphism	0,68	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6621	6621	C	G	MI.3406	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	718	240	H	D	Cac/Gac	-20	0	0	probably_damaging	1	deleterious	0	neutral	-1,22	deleterious	-11,87	deleterious	-6,28	high_impact	5,3	damaging	0,48	damaging	0,02	deleterious	3,85	23,4	0,19	0,55	disease	0,76	disease	0,86	disease	0,82	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,43	0,9	3,31	6,76	N	0,41	N	0,97	disease_causing	0,61	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6621	6621	C	T	MI.3407	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	718	240	H	Y	Cac/Tac	-20	0	0	probably_damaging	0,99	deleterious	0	neutral	-1,21	deleterious	-11,5	deleterious	-4,18	high_impact	4,75	damaging	0,52	damaging	0,02	deleterious	3,78	23,4	0,29	0,55	disease	0,82	disease	0,9	disease	0,77	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,64	low_impact	-1,48	high_impact	3,29	0,46	0,9	3,31	6,76	N	0,45	N	0,72	polymorphism	0,63	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6622	6622	A	T	MI.3408	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	719	240	H	L	cAc/cTc	4,52	1	0	probably_damaging	0,99	deleterious	0	neutral	-1,22	deleterious	-12,15	deleterious	-7,67	high_impact	5,3	damaging	0,6	damaging	0,03	deleterious	3,82	23,4	0,19	0,55	disease	0,85	disease	0,93	disease	0,75	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,64	low_impact	-1,48	high_impact	3,8	0,38	0,9	3,31	6,76	P	0,49	N	0,92	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6622	6622	A	G	MI.3409	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	719	240	H	R	cAc/cGc	4,52	1	0	probably_damaging	0,99	deleterious	0	neutral	-1,22	deleterious	-11,87	deleterious	-5,58	high_impact	5,3	damaging	0,54	damaging	0,02	deleterious	3,03	22,3	0,31	0,55	disease	0,73	disease	0,9	disease	0,8	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,64	low_impact	-1,48	high_impact	3,8	0,49	0,9	3,31	6,76	P	0,5	N	0,85	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8686	8686	T	G	MI.341	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	160	54	S	A	Tca/Gca	-5,89	0	0	benign	0,03	neutral	0,55	neutral	4,41	neutral	0,26	neutral	-0,64	neutral_impact	0,46	neutral	0,92	neutral	0,85	deleterious	0,39	6,57	0,41	0,65	neutral	0,37	neutral	0,2	neutral	0,22	neutral	0,37	3	neutral	0,41	deleterious	0,76	neutral	-6	neutral	0,16	medium_impact	0,68	medium_impact	0,34	medium_impact	-0,7	0,53	0,9	28,32	24,19	N	0,34	N	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6622	6622	A	C	MI.3410	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	719	240	H	P	cAc/cCc	4,52	1	0	probably_damaging	1	deleterious	0	neutral	-1,22	deleterious	-12,5	deleterious	-6,99	high_impact	4,25	damaging	0,39	damaging	0,04	deleterious	3,22	22,7	0,18	0,55	disease	0,9	disease	0,89	disease	0,75	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	2,83	0,35	0,9	3,31	6,76	P	0,54	P	0,9	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6623	6623	C	G	MI.3411	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	720	240	H	Q	caC/caG	8,69	1	0	probably_damaging	1	deleterious	0	neutral	-1,22	deleterious	-12,49	deleterious	-5,58	high_impact	4,75	damaging	0,57	damaging	0,02	deleterious	3,61	23,2	0,3	0,55	disease	0,67	disease	0,82	disease	0,75	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,57	0,9	3,31	6,76	P	0,52	P	0,83	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6623	6623	C	A	MI.3412	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	720	240	H	Q	caC/caA	8,69	1	0	probably_damaging	1	deleterious	0	neutral	-1,22	deleterious	-12,49	deleterious	-5,58	high_impact	4,75	damaging	0,57	damaging	0,02	deleterious	3,91	23,5	0,3	0,55	disease	0,67	disease	0,82	disease	0,75	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,57	0,9	3,31	6,76	P	0,52	P	0,83	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6624	6624	C	G	MI.3413	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	721	241	P	A	Cct/Gct	-0,33	0,35	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-3,51	deleterious	-5,54	high_impact	5,31	neutral	0,7	damaging	0,13	deleterious	3,07	22,4	0,19	0,55	disease	0,69	disease	0,79	disease	0,68	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,7	0,9	4,09	7,83	P	0,61	P	0,76	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6624	6624	C	A	MI.3414	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	721	241	P	T	Cct/Act	-0,33	0,35	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-4,6	deleterious	-5,54	high_impact	5,31	neutral	0,66	damaging	0,09	deleterious	3,86	23,5	0,25	0,55	neutral	0,37	disease	0,87	disease	0,57	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,68	0,9	4,09	7,83	P	0,53	P	0,8	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6624	6624	C	T	MI.3415	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	721	241	P	S	Cct/Tct	-0,33	0,35	0	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-3,84	deleterious	-5,54	high_impact	5,31	neutral	0,74	damaging	0,12	deleterious	3,85	23,4	0,32	0,55	disease	0,73	disease	0,85	disease	0,66	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,36	0,9	4,09	7,83	P	0,63	P	0,85	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6625	6625	C	T	MI.3416	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	722	241	P	L	cCt/cTt	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,73	deleterious	-4,96	deleterious	-6,92	high_impact	5,31	damaging	0,53	damaging	0,11	deleterious	4,32	24	0,24	0,55	disease	0,9	disease	0,91	disease	0,63	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,8	0,9	4,09	7,83	P	0,63	P	0,87	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6625	6625	C	A	MI.3417	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	722	241	P	H	cCt/cAt	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-6,29	deleterious	-6,25	high_impact	4,96	neutral	0,66	damaging	0,07	deleterious	3,98	23,6	0,22	0,55	disease	0,95	disease	0,91	disease	0,75	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,62	0,9	4,09	7,83	P	0,63	P	0,81	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6625	6625	C	G	MI.3418	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	722	241	P	R	cCt/cGt	5,45	1	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-4,87	deleterious	-6,25	high_impact	5,31	neutral	0,65	damaging	0,08	deleterious	3,63	23,2	0,17	0,55	disease	0,91	disease	0,93	disease	0,78	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,64	0,9	4,09	7,83	P	0,66	P	0,9	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6627	6627	G	A	MI.3419	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	724	242	E	K	Gaa/Aaa	-14,22	0	0	benign	0,04	deleterious	0	neutral	2,54	neutral	-2,49	deleterious	-2,75	high_impact	4,39	damaging	0,43	damaging	0,14	deleterious	4,5	24,3	0,31	0,55	neutral	0,28	disease	0,9	disease	0,66	disease	0,67	3	deleterious	1	deleterious	0,48	deleterious	2	neutral	0,3	medium_impact	0,54	low_impact	-1,48	high_impact	2,95	0,65	0,9	2,92	7,1	N	0,46	N	0,72	polymorphism	0,91	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8686	8686	T	A	MI.342	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	160	54	S	T	Tca/Aca	-5,89	0	0	benign	0,13	neutral	0,52	neutral	4,42	neutral	-0,47	neutral	1,15	neutral_impact	-0,96	neutral	0,86	neutral	0,94	neutral	-0,91	0,02	0,32	0,65	neutral	0,46	neutral	0,07	neutral	0,13	neutral	0,25	5	neutral	0,39	deleterious	0,7	neutral	-6	neutral	0,18	medium_impact	0,03	medium_impact	0,31	low_impact	-1,92	0,65	0,9	28,32	24,19	N	0,43	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6627	6627	G	C	MI.3420	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	724	242	E	Q	Gaa/Caa	-14,22	0	0	possibly_damaging	0,47	deleterious	0	neutral	2,52	neutral	-2,97	neutral	-2,07	high_impact	4,59	damaging	0,57	damaging	0,13	deleterious	3,4	23	0,38	0,55	disease	0,52	disease	0,8	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,27	deleterious	5	deleterious	0,6	medium_impact	-0,71	low_impact	-1,48	high_impact	3,14	0,85	0,9	2,92	7,1	N	0,4	N	0,66	polymorphism	0,98	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6628	6628	A	G	MI.3421	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	725	242	E	G	gAa/gGa	6,14	1	0	possibly_damaging	0,66	deleterious	0	neutral	2,51	deleterious	-3,36	deleterious	-4,83	high_impact	5,29	damaging	0,49	damaging	0,16	deleterious	4,34	24	0,27	0,55	disease	0,66	disease	0,81	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	5	deleterious	0,72	low_impact	-1,03	low_impact	-1,48	high_impact	3,79	0,59	0,9	2,92	7,1	P	0,68	P	0,67	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6628	6628	A	C	MI.3422	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	725	242	E	A	gAa/gCa	6,14	1	0	possibly_damaging	0,55	deleterious	0	neutral	2,63	neutral	-1,15	deleterious	-4,12	high_impact	3,98	neutral	0,63	damaging	0,16	deleterious	3,77	23,4	0,23	0,55	neutral	0,33	disease	0,82	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,23	deleterious	5	deleterious	0,53	medium_impact	-0,84	low_impact	-1,48	high_impact	2,58	0,72	0,9	2,92	7,1	P	0,51	P	0,71	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6628	6628	A	T	MI.3423	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	725	242	E	V	gAa/gTa	6,14	1	0	possibly_damaging	0,75	deleterious	0	neutral	2,6	neutral	-1,54	deleterious	-4,84	high_impact	5,29	damaging	0,53	damaging	0,13	deleterious	4,28	24	0,22	0,55	neutral	0,4	disease	0,93	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,13	deleterious	5	deleterious	0,67	low_impact	-1,21	low_impact	-1,48	high_impact	3,79	0,73	0,9	2,92	7,1	P	0,65	P	0,67	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6629	6629	A	T	MI.3424	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	726	242	E	D	gaA/gaT	8,69	1	0	benign	0,16	deleterious	0	neutral	2,51	deleterious	-3,37	neutral	-2,07	high_impact	4,95	damaging	0,58	damaging	0,13	deleterious	3,91	23,5	0,39	0,55	disease	0,55	disease	0,8	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,42	deleterious	2	neutral	0,37	medium_impact	-0,08	low_impact	-1,48	high_impact	3,47	0,86	0,9	2,92	7,1	P	0,63	P	0,69	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6629	6629	A	C	MI.3425	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	726	242	E	D	gaA/gaC	8,69	1	0	benign	0,16	deleterious	0	neutral	2,51	deleterious	-3,37	neutral	-2,07	high_impact	4,95	damaging	0,58	damaging	0,13	deleterious	3,75	23,3	0,39	0,55	disease	0,55	disease	0,8	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,42	deleterious	2	neutral	0,37	medium_impact	-0,08	low_impact	-1,48	high_impact	3,47	0,86	0,9	2,92	7,1	P	0,63	P	0,69	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6630	6630	G	C	MI.3426	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	727	243	V	L	Gtt/Ctt	2,67	1	0	probably_damaging	0,95	deleterious	0	neutral	1,88	deleterious	-4,27	neutral	-2,05	high_impact	5,31	neutral	0,64	damaging	0,14	deleterious	3,53	23,1	0,35	0,55	disease	0,7	disease	0,81	disease	0,55	disease	0,68	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,79	low_impact	-1,96	low_impact	-1,48	high_impact	3,8	0,76	0,9	1,75	6,65	P	0,68	P	0,55	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6630	6630	G	A	MI.3427	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	727	243	V	I	Gtt/Att	2,67	1	0	probably_damaging	0,95	deleterious	0	neutral	1,88	deleterious	-3,52	neutral	-0,68	high_impact	4,96	neutral	0,7	damaging	0,16	deleterious	3,65	23,2	0,43	0,55	disease	0,57	disease	0,69	disease	0,56	disease	0,64	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,74	low_impact	-1,96	low_impact	-1,48	high_impact	3,48	0,86	0,9	1,75	6,65	P	0,68	P	0,24	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6630	6630	G	T	MI.3428	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	727	243	V	F	Gtt/Ttt	2,67	1	0	probably_damaging	1	deleterious	0	neutral	1,78	deleterious	-6,04	deleterious	-3,41	high_impact	4,96	neutral	0,62	damaging	0,11	deleterious	3,86	23,5	0,15	0,55	disease	0,88	disease	0,92	disease	0,6	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,66	0,9	1,75	6,65	P	0,66	P	0,86	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6631	6631	T	G	MI.3429	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	728	243	V	G	gTt/gGt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	1,78	deleterious	-6,77	deleterious	-4,8	high_impact	4,96	neutral	0,65	damaging	0,17	deleterious	3,87	23,5	0,13	0,55	disease	0,85	disease	0,79	disease	0,62	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,56	0,9	1,75	6,65	P	0,66	P	0,71	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8687	8687	C	T	MI.343	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	161	54	S	L	tCa/tTa	-0,33	0	0	benign	0	neutral	0,68	neutral	4,43	neutral	-1,43	neutral	-0,24	neutral_impact	0,61	neutral	0,98	neutral	0,89	deleterious	0,82	9,59	0,3	0,65	neutral	0,45	neutral	0,42	neutral	0,25	neutral	0,47	1	neutral	0,31	deleterious	0,84	neutral	-6	neutral	0,18	high_impact	2,09	medium_impact	0,48	medium_impact	-0,58	0,78	0,9	28,32	24,19	N	0,31	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6631	6631	T	C	MI.3430	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	728	243	V	A	gTt/gCt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	1,85	deleterious	-4,96	deleterious	-2,72	high_impact	5,31	damaging	0,54	damaging	0,18	deleterious	3,63	23,2	0,31	0,55	disease	0,63	disease	0,72	disease	0,58	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,52	0,9	1,75	6,65	P	0,7	P	0,47	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6631	6631	T	A	MI.3431	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	728	243	V	D	gTt/gAt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	1,77	deleterious	-7,92	deleterious	-4,8	high_impact	5,31	neutral	0,71	damaging	0,13	deleterious	4,75	24,7	0,1	0,55	disease	0,94	disease	0,88	disease	0,66	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,49	0,9	1,75	6,65	P	0,67	P	0,83	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6633	6633	T	C	MI.3432	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	730	244	Y	H	Tat/Cat	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,29	deleterious	-6,06	deleterious	-3,41	high_impact	4,61	damaging	0,58	damaging	0,05	deleterious	3,55	23,1	0,25	0,55	disease	0,9	disease	0,83	disease	0,74	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,16	0,54	0,9	2,53	6,64	N	0,36	N	0,61	polymorphism	0,79	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6633	6633	T	G	MI.3433	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	730	244	Y	D	Tat/Gat	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,33	deleterious	-6,45	deleterious	-6,83	high_impact	5,3	damaging	0,47	damaging	0,05	deleterious	3,95	23,6	0,14	0,55	disease	0,94	disease	0,86	disease	0,79	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,32	0,9	2,53	6,64	P	0,48	N	0,98	disease_causing	0,69	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6633	6633	T	A	MI.3434	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	730	244	Y	N	Tat/Aat	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,32	deleterious	-5,62	deleterious	-6,14	high_impact	4,96	damaging	0,57	damaging	0,06	deleterious	4,01	23,6	0,22	0,55	disease	0,93	disease	0,86	disease	0,67	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,35	0,9	2,53	6,64	P	0,53	P	0,94	disease_causing	0,75	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6634	6634	A	G	MI.3435	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	731	244	Y	C	tAt/tGt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,27	deleterious	-7,85	deleterious	-6,16	high_impact	5,3	damaging	0,53	damaging	0,05	deleterious	3,57	23,2	0,24	0,55	disease	0,97	disease	0,87	disease	0,74	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,28	0,9	2,53	6,64	P	0,59	P	0,89	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6634	6634	A	T	MI.3436	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	731	244	Y	F	tAt/tTt	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,28	deleterious	-5,02	deleterious	-2,73	high_impact	5,3	damaging	0,56	damaging	0,06	deleterious	3,4	23	0,22	0,55	disease	0,7	disease	0,82	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	3,8	0,62	0,9	2,53	6,64	P	0,71	P	0,5	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6634	6634	A	C	MI.3437	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	731	244	Y	S	tAt/tCt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,32	deleterious	-5,73	deleterious	-6,13	high_impact	5,3	damaging	0,58	damaging	0,06	deleterious	3,74	23,3	0,2	0,55	disease	0,89	disease	0,82	disease	0,7	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,43	0,9	2,53	6,64	P	0,66	P	0,9	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6636	6636	A	C	MI.3438	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	733	245	I	L	Att/Ctt	-4,73	0	0	probably_damaging	0,97	deleterious	0	neutral	2,63	neutral	-2,24	neutral	-1,37	high_impact	4,54	neutral	0,68	damaging	0,06	deleterious	1,81	15,02	0,26	0,55	disease	0,56	disease	0,73	disease	0,52	disease	0,57	1	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,71	low_impact	-2,18	low_impact	-1,48	high_impact	3,09	0,67	0,9	2,53	6,9	N	0,38	N	0,61	disease_causing	0,97	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6636	6636	A	G	MI.3439	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	733	245	I	V	Att/Gtt	-4,73	0	0	probably_damaging	0,92	neutral	0,26	neutral	2,6	neutral	-2,1	neutral	-0,69	medium_impact	3,02	neutral	0,64	damaging	0,09	neutral	1,01	10,69	0,32	0,55	neutral	0,35	disease	0,57	neutral	0,42	neutral	0,45	1	neutral	0,93	neutral	0,17	deleterious	1	deleterious	0,62	low_impact	-1,76	medium_impact	-0,06	medium_impact	1,69	0,68	0,9	2,53	6,9	N	0,35	N	0,23	disease_causing	0,94	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8687	8687	C	G	MI.344	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	161	54	S	W	tCa/tGa	-0,33	0	0	possibly_damaging	0,74	neutral	0,18	neutral	4,3	deleterious	-4,62	deleterious	-2,68	low_impact	1,34	neutral	0,86	neutral	0,42	deleterious	3,98	23,6	0,2	0,65	disease	0,94	disease	0,73	disease	0,54	disease	0,82	6	neutral	0,87	neutral	0,22	neutral	-3	deleterious	0,73	low_impact	-1,19	medium_impact	-0,08	medium_impact	0,05	0,51	0,9	28,32	24,19	N	0,31	N	0,57	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6636	6636	A	T	MI.3440	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	733	245	I	F	Att/Ttt	-4,73	0	0	probably_damaging	1	deleterious	0	neutral	2,49	neutral	-1,76	deleterious	-2,73	high_impact	4,89	neutral	0,63	damaging	0,05	deleterious	3,35	22,9	0,17	0,55	disease	0,61	disease	0,84	disease	0,64	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,42	0,76	0,9	2,53	6,9	P	0,63	P	0,85	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6637	6637	T	G	MI.3441	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	734	245	I	S	aTt/aGt	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-3,97	deleterious	-4,1	high_impact	5,24	neutral	0,66	damaging	0,09	deleterious	4,14	23,8	0,15	0,55	disease	0,91	disease	0,85	disease	0,61	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,48	0,9	2,53	6,9	P	0,7	P	0,62	disease_causing	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6637	6637	T	C	MI.3442	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	734	245	I	T	aTt/aCt	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-3,59	deleterious	-3,42	high_impact	4,34	neutral	0,64	damaging	0,07	deleterious	3,08	22,5	0,2	0,55	disease	0,83	disease	0,8	disease	0,56	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,91	0,55	0,9	2,53	6,9	N	0,43	N	0,76	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6637	6637	T	A	MI.3443	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	734	245	I	N	aTt/aAt	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-5,2	deleterious	-4,8	high_impact	5,24	neutral	0,62	damaging	0,07	deleterious	4,36	24,1	0,14	0,55	disease	0,95	disease	0,87	disease	0,64	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,48	0,9	2,53	6,9	P	0,69	P	0,94	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6638	6638	T	A	MI.3444	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	735	245	I	M	atT/atA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-3,53	neutral	-2,05	high_impact	4,89	neutral	0,67	damaging	0,07	deleterious	3,68	23,3	0,21	0,55	disease	0,81	disease	0,68	disease	0,55	disease	0,64	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,42	0,71	0,9	2,53	6,9	P	0,71	P	0,76	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6638	6638	T	G	MI.3445	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	735	245	I	M	atT/atG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-3,53	neutral	-2,05	high_impact	4,89	neutral	0,67	damaging	0,07	deleterious	3,32	22,9	0,21	0,55	disease	0,81	disease	0,68	disease	0,55	disease	0,64	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,42	0,71	0,9	2,53	6,9	P	0,69	P	0,76	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6639	6639	C	T	MI.3446	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	736	246	L	F	Ctt/Ttt	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	2,59	neutral	-2,91	deleterious	-2,75	high_impact	4,42	damaging	0,52	damaging	0,03	deleterious	3,96	23,6	0,33	0,55	disease	0,56	disease	0,81	disease	0,57	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,98	0,71	0,9	2,14	6,71	N	0,37	N	0,87	disease_causing	0,6	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6639	6639	C	G	MI.3447	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	736	246	L	V	Ctt/Gtt	-1,03	0	0	probably_damaging	0,99	deleterious	0	neutral	2,78	neutral	-0,44	neutral	-2,06	high_impact	3,64	damaging	0,52	damaging	0,04	deleterious	3,43	23	0,32	0,55	neutral	0,26	disease	0,76	disease	0,56	disease	0,62	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-2,64	low_impact	-1,48	high_impact	2,26	0,77	0,9	2,14	6,71	N	0,3	N	0,66	polymorphism	0,77	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6639	6639	C	A	MI.3448	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	736	246	L	I	Ctt/Att	-1,03	0	0	probably_damaging	1	deleterious	0,04	neutral	2,69	neutral	-1,38	neutral	-1,38	medium_impact	3,27	damaging	0,55	damaging	0,04	deleterious	4,13	23,8	0,27	0,55	neutral	0,35	disease	0,76	neutral	0,41	disease	0,54	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,76	low_impact	-3,58	medium_impact	-0,58	medium_impact	1,92	0,74	0,9	2,14	6,71	N	0,31	N	0,54	polymorphism	0,86	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6640	6640	T	G	MI.3449	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	737	246	L	R	cTt/cGt	-0,8	0	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-3,98	deleterious	-4,13	high_impact	5,23	damaging	0,53	damaging	0,03	deleterious	4,14	23,8	0,13	0,55	disease	0,66	disease	0,93	disease	0,75	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,73	0,39	0,9	2,14	6,71	P	0,64	P	0,9	polymorphism	0,96	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8689	8689	A	G	MI.345	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	163	55	K	E	Aaa/Gaa	-3,8	0	0	probably_damaging	0,99	neutral	0,23	neutral	4,36	neutral	-0,38	deleterious	-2,9	medium_impact	2,21	neutral	0,88	neutral	0,47	deleterious	3,88	23,5	0,5	0,65	neutral	0,29	disease	0,77	neutral	0,5	disease	0,53	1	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,74	low_impact	-2,65	medium_impact	-0,01	medium_impact	0,8	0,65	0,9	49,12	8,68	N	0,33	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6640	6640	T	A	MI.3450	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	737	246	L	H	cTt/cAt	-0,8	0	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-4,52	deleterious	-4,81	high_impact	5,23	damaging	0,56	damaging	0,02	deleterious	4	23,6	0,13	0,55	disease	0,74	disease	0,86	disease	0,72	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,73	0,46	0,9	2,14	6,71	P	0,64	P	0,83	polymorphism	0,98	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6640	6640	T	C	MI.3451	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	737	246	L	P	cTt/cCt	-0,8	0	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-4,38	deleterious	-4,83	high_impact	4,68	damaging	0,41	damaging	0,05	deleterious	3,79	23,4	0,15	0,55	disease	0,68	disease	0,84	disease	0,64	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,22	0,58	0,9	2,14	6,71	P	0,51	P	0,83	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6642	6642	A	G	MI.3452	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	739	247	I	V	Atc/Gtc	-20	0	0	probably_damaging	0,95	deleterious	0,02	neutral	2,69	neutral	-0,65	neutral	-0,66	medium_impact	3,35	damaging	0,59	damaging	0,12	deleterious	3,07	22,4	0,5	0,55	neutral	0,35	disease	0,57	disease	0,59	disease	0,55	1	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,67	low_impact	-1,96	medium_impact	-0,75	medium_impact	1,99	0,77	0,9	7,02	8,29	N	0,35	N	0,23	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6642	6642	A	T	MI.3453	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	739	247	I	F	Atc/Ttc	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,63	neutral	-1,17	deleterious	-2,75	high_impact	4,55	damaging	0,59	damaging	0,11	deleterious	3,81	23,4	0,26	0,55	disease	0,5	disease	0,83	disease	0,68	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,1	0,85	0,9	7,02	8,29	N	0,41	N	0,85	polymorphism	0,51	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6642	6642	A	C	MI.3454	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	739	247	I	L	Atc/Ctc	-20	0	0	probably_damaging	0,98	deleterious	0	neutral	2,71	neutral	-0,53	neutral	-1,38	high_impact	5,24	neutral	0,62	damaging	0,09	deleterious	3,8	23,4	0,29	0,55	neutral	0,31	disease	0,7	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,7	low_impact	-2,35	low_impact	-1,48	high_impact	3,74	0,74	0,9	7,02	8,29	P	0,6	P	0,61	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6643	6643	T	A	MI.3455	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	740	247	I	N	aTc/aAc	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-4,43	deleterious	-4,83	high_impact	4,89	damaging	0,55	damaging	0,1	deleterious	4,36	24,1	0,19	0,55	disease	0,77	disease	0,84	disease	0,68	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,42	0,7	0,9	7,02	8,29	P	0,7	P	0,94	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6643	6643	T	G	MI.3456	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	740	247	I	S	aTc/aGc	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-3,18	deleterious	-4,12	high_impact	5,24	neutral	0,61	damaging	0,13	deleterious	4,24	23,9	0,2	0,55	disease	0,62	disease	0,85	disease	0,65	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,65	0,9	7,02	8,29	P	0,73	P	0,62	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6643	6643	T	C	MI.3457	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	740	247	I	T	aTc/aCc	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,52	neutral	-2,8	deleterious	-3,41	high_impact	5,24	neutral	0,6	damaging	0,09	deleterious	3,4	23	0,36	0,55	disease	0,57	disease	0,8	disease	0,67	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,75	0,9	7,02	8,29	P	0,7	P	0,76	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6644	6644	C	G	MI.3458	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	741	247	I	M	atC/atG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,52	neutral	-2,82	neutral	-2,05	high_impact	4,43	neutral	0,64	damaging	0,08	deleterious	3,42	23	0,3	0,55	disease	0,55	disease	0,68	disease	0,67	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,99	0,91	0,95	7,02	8,29	N	0,48	N	0,76	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6644	6644	C	A	MI.3459	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	741	247	I	M	atC/atA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,52	neutral	-2,82	neutral	-2,05	high_impact	4,43	neutral	0,64	damaging	0,08	deleterious	3,89	23,5	0,3	0,55	disease	0,55	disease	0,68	disease	0,67	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,99	0,91	0,95	7,02	8,29	N	0,48	N	0,76	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8689	8689	A	C	MI.346	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	163	55	K	Q	Aaa/Caa	-3,8	0	0	probably_damaging	1	neutral	0,36	neutral	4,3	neutral	-1,14	deleterious	-2,62	low_impact	1,18	neutral	0,85	neutral	0,64	deleterious	1,86	15,32	0,55	0,65	disease	0,59	neutral	0,48	neutral	0,33	disease	0,57	1	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	0,15	medium_impact	-0,09	0,75	0,9	49,12	8,68	N	0,3	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6645	6645	C	G	MI.3460	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	742	248	L	V	Cta/Gta	-4,5	0	0	probably_damaging	0,98	deleterious	0	neutral	2,4	deleterious	-3,15	neutral	-1,95	high_impact	4,53	damaging	0,53	damaging	0,06	deleterious	3,39	23	0,46	0,55	disease	0,59	disease	0,77	disease	0,58	disease	0,62	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,35	low_impact	-1,48	high_impact	3,08	0,72	0,9	7,8	8,21	N	0,38	N	0,66	disease_causing	0,72	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6645	6645	C	A	MI.3461	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	742	248	L	M	Cta/Ata	-4,5	0	0	probably_damaging	1	deleterious	0	neutral	2,35	deleterious	-3,48	neutral	-1,36	high_impact	4,12	damaging	0,57	damaging	0,07	deleterious	3,71	23,3	0,32	0,55	disease	0,66	disease	0,65	disease	0,56	disease	0,56	1	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,76	0,9	7,8	8,21	N	0,31	N	0,59	disease_causing	0,67	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6646	6646	T	C	MI.3462	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	743	248	L	P	cTa/cCa	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,31	deleterious	-6,38	deleterious	-4,82	high_impact	4,53	damaging	0,41	damaging	0,05	deleterious	3,9	23,5	0,16	0,55	disease	0,93	disease	0,85	disease	0,66	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,08	0,58	0,9	7,8	8,21	N	0,45	N	0,83	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6646	6646	T	G	MI.3463	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	743	248	L	R	cTa/cGa	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,32	deleterious	-5,81	deleterious	-4,15	high_impact	5,22	damaging	0,52	damaging	0,04	deleterious	4,19	23,8	0,16	0,55	disease	0,91	disease	0,92	disease	0,78	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,72	0,44	0,9	7,8	8,21	P	0,63	P	0,9	disease_causing	0,81	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6646	6646	T	A	MI.3464	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	743	248	L	Q	cTa/cAa	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,32	deleterious	-5,95	deleterious	-4,15	high_impact	5,22	damaging	0,56	damaging	0,05	deleterious	4,06	23,7	0,18	0,55	disease	0,91	disease	0,84	disease	0,67	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,72	0,68	0,9	7,8	8,21	P	0,61	P	0,82	disease_causing	0,77	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6648	6648	C	G	MI.3465	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	745	249	P	A	Cca/Gca	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-4,56	deleterious	-5,59	high_impact	4,61	neutral	0,69	damaging	0,09	deleterious	3,05	22,4	0,22	0,55	disease	0,81	disease	0,78	disease	0,72	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,16	0,61	0,9	6,43	8,06	N	0,38	N	0,76	polymorphism	0,89	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6648	6648	C	A	MI.3466	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	745	249	P	T	Cca/Aca	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-5,3	deleterious	-5,59	high_impact	4,75	neutral	0,68	damaging	0,06	deleterious	3,62	23,2	0,25	0,55	disease	0,87	disease	0,88	disease	0,67	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,66	0,9	6,43	8,06	N	0,53	P	0,8	polymorphism	0,85	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6648	6648	C	T	MI.3467	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	745	249	P	S	Cca/Tca	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-5,02	deleterious	-5,58	high_impact	4,5	neutral	0,68	damaging	0,06	deleterious	3,85	23,4	0,31	0,55	disease	0,84	disease	0,87	disease	0,71	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,31	0,9	6,43	8,06	N	0,36	N	0,85	polymorphism	0,84	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6649	6649	C	T	MI.3468	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	746	249	P	L	cCa/cTa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-6,93	deleterious	-7	high_impact	5,3	neutral	0,7	damaging	0,03	deleterious	4,32	24	0,26	0,55	disease	0,86	disease	0,91	disease	0,7	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,65	0,9	6,43	8,06	P	0,65	P	0,87	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6649	6649	C	G	MI.3469	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	746	249	P	R	cCa/cGa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-6,93	deleterious	-6,3	high_impact	5,3	neutral	0,66	damaging	0,05	deleterious	3,53	23,1	0,16	0,55	disease	0,92	disease	0,93	disease	0,82	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,62	0,9	6,43	8,06	P	0,63	P	0,9	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8690	8690	A	C	MI.347	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	164	55	K	T	aAa/aCa	2,44	0,98	0	probably_damaging	0,99	neutral	0,22	neutral	4,31	neutral	-0,97	deleterious	-4,68	medium_impact	2,09	neutral	0,84	neutral	0,52	deleterious	3,47	23	0,32	0,65	disease	0,67	disease	0,72	neutral	0,45	neutral	0,5	0	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,8	low_impact	-2,65	medium_impact	-0,02	medium_impact	0,69	0,44	0,9	49,12	8,68	N	0,44	N	0,81	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6649	6649	C	A	MI.3470	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	746	249	P	Q	cCa/cAa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-6,81	deleterious	-5,6	high_impact	5,3	neutral	0,68	damaging	0,05	deleterious	4,1	23,7	0,18	0,55	disease	0,94	disease	0,88	disease	0,75	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,55	0,9	6,43	8,06	P	0,65	P	0,82	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6651	6651	G	T	MI.3471	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	748	250	G	C	Ggc/Tgc	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-3,07	deleterious	-5,7	high_impact	5,05	damaging	0,55	damaging	0,05	deleterious	4,15	23,8	0,19	0,55	disease	0,64	disease	0,9	disease	0,67	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,61	0,9	5,46	8,31	P	0,59	P	0,98	disease_causing	0,93	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6651	6651	G	A	MI.3472	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	748	250	G	S	Ggc/Agc	-3,34	0	0	probably_damaging	1	deleterious	0,01	neutral	2,76	neutral	-0,71	deleterious	-3,72	high_impact	4,5	neutral	0,66	damaging	0,07	deleterious	4,17	23,8	0,24	0,55	neutral	0,28	disease	0,85	disease	0,59	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-3,58	medium_impact	-0,92	high_impact	3,06	0,63	0,9	5,46	8,31	N	0,38	N	0,73	disease_causing	0,76	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6651	6651	G	C	MI.3473	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	748	250	G	R	Ggc/Cgc	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-1,58	deleterious	-5,14	high_impact	5,05	damaging	0,48	damaging	0,08	deleterious	3,97	23,6	0,14	0,55	neutral	0,45	disease	0,92	disease	0,78	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,68	0,9	5,46	8,31	P	0,67	P	0,95	disease_causing	0,87	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6652	6652	G	T	MI.3474	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	749	250	G	V	gGc/gTc	9,15	1	0	probably_damaging	1	neutral	0,05	neutral	2,84	neutral	-0,28	deleterious	-5,7	high_impact	3,73	damaging	0,56	damaging	0,06	deleterious	3,75	23,3	0,19	0,55	neutral	0,24	disease	0,92	disease	0,68	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,84	low_impact	-3,58	medium_impact	-0,52	high_impact	2,35	0,55	0,9	5,46	8,31	N	0,45	N	0,93	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6652	6652	G	A	MI.3475	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	749	250	G	D	gGc/gAc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-2,36	deleterious	-4,58	high_impact	5,05	damaging	0,59	damaging	0,05	deleterious	3,85	23,4	0,18	0,55	disease	0,53	disease	0,9	disease	0,78	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,45	0,9	5,46	8,31	P	0,75	P	0,97	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6652	6652	G	C	MI.3476	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	749	250	G	A	gGc/gCc	9,15	1	0	probably_damaging	1	neutral	0,24	neutral	3,08	neutral	2,15	deleterious	-3,5	low_impact	1,5	damaging	0,54	damaging	0,25	deleterious	1,95	15,89	0,34	0,55	neutral	0,23	disease	0,59	neutral	0,41	neutral	0,42	2	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,75	low_impact	-3,58	medium_impact	-0,09	medium_impact	0,29	0,63	0,9	5,46	8,31	P	0,5	N	0,64	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6654	6654	T	A	MI.3477	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	751	251	F	I	Ttc/Atc	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,64	neutral	-1,79	deleterious	-4,22	high_impact	4,75	neutral	0,69	damaging	0,11	deleterious	4,45	24,2	0,23	0,55	neutral	0,39	disease	0,88	disease	0,69	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,62	0,9	2,53	6,91	P	0,62	P	0,88	polymorphism	0,82	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6654	6654	T	C	MI.3478	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	751	251	F	L	Ttc/Ctc	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-0,98	deleterious	-4,22	high_impact	4,5	neutral	0,67	damaging	0,1	deleterious	4,1	23,7	0,4	0,55	neutral	0,36	disease	0,85	disease	0,69	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,58	0,9	2,53	6,91	N	0,42	N	0,83	polymorphism	0,81	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6654	6654	T	G	MI.3479	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	751	251	F	V	Ttc/Gtc	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,62	neutral	-1,34	deleterious	-4,92	high_impact	5,3	neutral	0,62	damaging	0,1	deleterious	4,14	23,8	0,29	0,55	neutral	0,42	disease	0,92	disease	0,75	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,58	0,9	2,53	6,91	P	0,63	P	0,84	polymorphism	0,69	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8690	8690	A	T	MI.348	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	164	55	K	M	aAa/aTa	2,44	0,98	0	probably_damaging	1	deleterious	0,02	neutral	4,24	deleterious	-3,32	deleterious	-4,72	medium_impact	2,56	neutral	0,86	neutral	0,57	deleterious	3,68	23,3	0,25	0,65	disease	0,87	disease	0,69	neutral	0,34	disease	0,61	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-3,6	medium_impact	-0,66	medium_impact	1,1	0,41	0,9	49,12	8,68	N	0,45	N	0,53	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6655	6655	T	C	MI.3480	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	752	251	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,54	neutral	-2,99	deleterious	-5,62	high_impact	4,95	neutral	0,63	damaging	0,14	deleterious	4,26	23,9	0,28	0,55	disease	0,57	disease	0,88	disease	0,74	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,47	0,33	0,9	2,53	6,91	P	0,73	P	0,84	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6655	6655	T	A	MI.3481	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	752	251	F	Y	tTc/tAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,52	neutral	-1,2	neutral	-2,11	high_impact	4,61	neutral	0,67	damaging	0,1	deleterious	4,3	24	0,25	0,55	neutral	0,42	disease	0,84	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,16	0,63	0,9	2,53	6,91	P	0,54	P	0,59	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6655	6655	T	G	MI.3482	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	752	251	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-4,33	deleterious	-5,64	high_impact	5,3	neutral	0,64	damaging	0,1	deleterious	4,13	23,8	0,25	0,55	disease	0,78	disease	0,87	disease	0,77	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,27	0,9	2,53	6,91	P	0,72	P	0,91	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6656	6656	C	A	MI.3483	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	753	251	F	L	ttC/ttA	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-0,98	deleterious	-4,22	high_impact	4,5	neutral	0,67	damaging	0,1	deleterious	4,65	24,5	0,4	0,55	neutral	0,36	disease	0,85	disease	0,69	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,58	0,9	2,53	6,91	P	0,53	P	0,83	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6656	6656	C	G	MI.3484	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	753	251	F	L	ttC/ttG	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-0,98	deleterious	-4,22	high_impact	4,5	neutral	0,67	damaging	0,1	deleterious	4,37	24,1	0,4	0,55	neutral	0,36	disease	0,85	disease	0,69	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,58	0,9	2,53	6,91	P	0,5	N	0,83	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6657	6657	G	T	MI.3485	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	754	252	G	W	Gga/Tga	-5,66	0	0	probably_damaging	1	deleterious	0	neutral	1,84	deleterious	-10,16	deleterious	-5,7	high_impact	4,96	damaging	0,56	damaging	0,06	deleterious	4,46	24,2	0,15	0,55	disease	0,97	disease	0,93	disease	0,79	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,93	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,26	0,9	4,48	7,98	N	0,47	N	0,83	disease_causing	0,99	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6657	6657	G	C	MI.3486	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	754	252	G	R	Gga/Cga	-5,66	0	0	probably_damaging	1	deleterious	0	neutral	1,85	deleterious	-7,33	deleterious	-5,69	high_impact	5,31	damaging	0,46	damaging	0,07	deleterious	3,95	23,6	0,11	0,55	disease	0,85	disease	0,93	disease	0,82	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,93	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,64	0,9	4,48	7,98	P	0,55	P	0,95	disease_causing	0,99	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6658	6658	G	A	MI.3487	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	755	252	G	E	gGa/gAa	6,14	1	0	probably_damaging	1	deleterious	0	neutral	1,85	deleterious	-7,16	deleterious	-5,69	high_impact	5,31	damaging	0,51	damaging	0,06	deleterious	3,84	23,4	0,14	0,55	disease	0,81	disease	0,91	disease	0,83	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,53	0,9	4,48	7,98	P	0,64	P	0,93	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6658	6658	G	C	MI.3488	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	755	252	G	A	gGa/gCa	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,31	neutral	-1,3	deleterious	-4,26	high_impact	4,5	neutral	0,7	damaging	0,1	deleterious	3,11	22,5	0,18	0,55	neutral	0,49	disease	0,77	disease	0,75	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,56	0,9	4,48	7,98	P	0,53	P	0,64	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6658	6658	G	T	MI.3489	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	755	252	G	V	gGa/gTa	6,14	1	0	probably_damaging	1	deleterious	0	neutral	1,86	deleterious	-6,22	deleterious	-6,41	high_impact	5,31	damaging	0,54	damaging	0,05	deleterious	3,72	23,3	0,13	0,55	disease	0,54	disease	0,93	disease	0,77	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,48	0,9	4,48	7,98	P	0,56	P	0,93	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8691	8691	A	T	MI.349	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	165	55	K	N	aaA/aaT	8,69	1	0	probably_damaging	1	neutral	0,32	neutral	4,48	neutral	0,64	deleterious	-3,46	low_impact	0,92	neutral	0,8	neutral	0,53	deleterious	2,67	20,6	0,67	0,75	disease	0,57	disease	0,6	neutral	0,34	neutral	0,5	0	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,77	low_impact	-3,6	medium_impact	0,11	medium_impact	-0,31	0,64	0,9	49,12	8,68	N	0,47	N	0,77	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6660	6660	A	G	MI.3490	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	757	253	M	V	Ata/Gta	-5,66	0	0	benign	0	deleterious	0,01	neutral	2,99	neutral	0,92	neutral	-1,44	low_impact	1,55	neutral	0,68	neutral	0,3	deleterious	0,85	9,74	0,57	0,6	neutral	0,17	disease	0,83	neutral	0,43	disease	0,52	0	deleterious	0,99	deleterious	0,51	neutral	-2	neutral	0,18	high_impact	2,07	medium_impact	-0,92	medium_impact	0,33	0,42	0,9	9,36	35,81	N	0,35	N	0,27	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6660	6660	A	T	MI.3491	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	757	253	M	L	Ata/Tta	-5,66	0	0	benign	0,01	neutral	0,22	neutral	2,97	neutral	0,94	neutral	-0,91	neutral_impact	0,33	neutral	0,64	neutral	0,4	deleterious	0,28	5,54	0,44	0,55	neutral	0,17	disease	0,68	neutral	0,36	neutral	0,44	1	neutral	0,77	deleterious	0,61	neutral	-6	neutral	0,17	medium_impact	1,12	medium_impact	-0,11	medium_impact	-0,79	0,43	0,9	9,36	35,81	N	0,4	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6660	6660	A	C	MI.3492	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	757	253	M	L	Ata/Cta	-5,66	0	0	benign	0,01	neutral	0,22	neutral	2,97	neutral	0,94	neutral	-0,91	neutral_impact	0,33	neutral	0,64	neutral	0,4	deleterious	0,18	4,46	0,44	0,55	neutral	0,17	disease	0,68	neutral	0,36	neutral	0,44	1	neutral	0,77	deleterious	0,61	neutral	-6	neutral	0,17	medium_impact	1,12	medium_impact	-0,11	medium_impact	-0,79	0,43	0,9	9,36	35,81	N	0,39	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6661	6661	T	C	MI.3493	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	758	253	M	T	aTa/aCa	7,07	1	0	benign	0,16	deleterious	0	neutral	2,79	neutral	-0,89	deleterious	-3,17	high_impact	3,52	neutral	0,62	damaging	0,17	neutral	1,12	11,35	0,44	0,55	neutral	0,31	disease	0,84	disease	0,64	disease	0,74	5	deleterious	1	neutral	0,42	deleterious	2	neutral	0,3	medium_impact	-0,08	low_impact	-1,48	high_impact	2,15	0,38	0,9	9,36	35,81	P	0,52	P	0,67	disease_causing	0,64	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6661	6661	T	A	MI.3494	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	758	253	M	K	aTa/aAa	7,07	1	0	benign	0,14	deleterious	0	neutral	2,75	neutral	-2,23	deleterious	-3,64	high_impact	4,22	damaging	0,6	damaging	0,11	deleterious	2,24	17,75	0,17	0,55	neutral	0,49	disease	0,91	disease	0,71	disease	0,79	6	deleterious	1	neutral	0,43	deleterious	2	neutral	0,39	medium_impact	-0,01	low_impact	-1,48	high_impact	2,8	0,33	0,9	9,36	35,81	P	0,5	N	0,73	disease_causing	0,93	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6662	6662	A	C	MI.3495	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	759	253	M	I	atA/atC	7,53	1	0	benign	0,02	neutral	1	neutral	3,03	neutral	1,79	neutral	-1,18	neutral_impact	-0,06	neutral	0,69	neutral	0,97	neutral	-0,26	0,83	0,55	0,6	neutral	0,29	neutral	0,43	neutral	0,31	neutral	0,45	1	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,15	medium_impact	0,83	high_impact	1,86	low_impact	-1,15	0,53	0,9	9,36	35,81	P	0,53	P	0	disease_causing	0,92	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6662	6662	A	T	MI.3496	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	759	253	M	I	atA/atT	7,53	1	0	benign	0,02	neutral	1	neutral	3,03	neutral	1,79	neutral	-1,18	neutral_impact	-0,06	neutral	0,69	neutral	0,97	neutral	-0,2	1,11	0,55	0,6	neutral	0,29	neutral	0,43	neutral	0,31	neutral	0,45	1	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,15	medium_impact	0,83	high_impact	1,86	low_impact	-1,15	0,53	0,9	9,36	35,81	P	0,54	P	0	disease_causing	0,92	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6663	6663	A	G	MI.3497	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	760	254	I	V	Atc/Gtc	-0,57	0,09	0	benign	0	neutral	0,25	neutral	2,85	neutral	0,23	neutral	-0,44	low_impact	1,29	neutral	0,67	neutral	0,8	deleterious	-0,05	2,1	0,62	0,65	neutral	0,29	neutral	0,37	neutral	0,42	neutral	0,39	2	neutral	0,75	deleterious	0,63	neutral	-6	neutral	0,16	high_impact	2,07	medium_impact	-0,07	medium_impact	0,09	0,77	0,9	12,87	13,9	P	0,55	P	0,17	disease_causing	0,92	0,01	rs200784106	.	.	.	.	.	.	.	2,97	A6663G	Prostate Cancer	+	-	Reported	3
chrM	6663	6663	A	T	MI.3498	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	760	254	I	F	Atc/Ttc	-0,57	0,09	0	possibly_damaging	0,56	deleterious	0	neutral	2,65	neutral	-1,65	deleterious	-2,84	high_impact	4,07	neutral	0,62	neutral	0,42	deleterious	3,45	23	0,28	0,55	neutral	0,41	disease	0,89	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,22	deleterious	5	deleterious	0,73	medium_impact	-0,86	low_impact	-1,48	high_impact	2,66	0,83	0,9	12,87	13,9	N	0,47	N	0,84	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6663	6663	A	C	MI.3499	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	760	254	I	L	Atc/Ctc	-0,57	0,09	0	benign	0,08	deleterious	0	neutral	2,82	neutral	0,08	neutral	-1,42	high_impact	4	neutral	0,64	neutral	0,46	deleterious	1,92	15,74	0,36	0,55	neutral	0,34	disease	0,81	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,46	deleterious	2	neutral	0,26	medium_impact	0,24	low_impact	-1,48	high_impact	2,59	0,79	0,9	12,87	13,9	N	0,5	N	0,36	disease_causing	0,96	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8542	8542	T	G	MI.35	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	16	6	F	V	Ttc/Gtc	0,13	0,97	0	probably_damaging	0,95	deleterious	0	neutral	3,93	neutral	-1,04	deleterious	-5,93	medium_impact	3,32	damaging	0,47	neutral	0,62	deleterious	3,95	23,6	0,42	0,65	disease	0,73	disease	0,73	disease	0,8	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,77	low_impact	-1,97	low_impact	-1,4	medium_impact	1,75	0,29	0,9	39,82	8,43	P	0,51	P	0,98	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8691	8691	A	C	MI.350	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	165	55	K	N	aaA/aaC	8,69	1	0	probably_damaging	1	neutral	0,32	neutral	4,48	neutral	0,64	deleterious	-3,46	low_impact	0,92	neutral	0,8	neutral	0,53	deleterious	2,64	20,5	0,67	0,75	disease	0,57	disease	0,6	neutral	0,34	neutral	0,5	0	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,77	low_impact	-3,6	medium_impact	0,11	medium_impact	-0,31	0,64	0,9	49,12	8,68	N	0,46	N	0,77	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6664	6664	T	G	MI.3500	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	761	254	I	S	aTc/aGc	5,91	1	0	possibly_damaging	0,8	deleterious	0	neutral	2,61	neutral	-2,59	deleterious	-4,11	high_impact	5,04	neutral	0,73	neutral	0,51	deleterious	4,07	23,7	0,25	0,55	disease	0,64	disease	0,9	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,1	deleterious	5	deleterious	0,83	low_impact	-1,32	low_impact	-1,48	high_impact	3,56	0,59	0,9	12,87	13,9	P	0,69	P	0,7	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6664	6664	T	A	MI.3501	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	761	254	I	N	aTc/aAc	5,91	1	0	probably_damaging	0,95	deleterious	0	neutral	2,59	deleterious	-3,84	deleterious	-4,83	high_impact	4,7	neutral	0,63	neutral	0,43	deleterious	4,56	24,4	0,23	0,55	disease	0,79	disease	0,89	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,85	low_impact	-1,96	low_impact	-1,48	high_impact	3,24	0,63	0,9	12,87	13,9	P	0,61	P	0,82	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6664	6664	T	C	MI.3502	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	761	254	I	T	aTc/aCc	5,91	1	0	possibly_damaging	0,54	deleterious	0	neutral	2,66	neutral	-1,5	deleterious	-3,26	high_impact	4,24	neutral	0,65	neutral	0,45	deleterious	3,08	22,5	0,4	0,55	disease	0,58	disease	0,83	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,23	deleterious	5	deleterious	0,72	medium_impact	-0,82	low_impact	-1,48	high_impact	2,82	0,72	0,9	12,87	13,9	P	0,51	P	0,81	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6665	6665	C	G	MI.3503	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	762	254	I	M	atC/atG	7,53	1	0,01	possibly_damaging	0,8	deleterious	0,03	neutral	2,66	neutral	-1,4	neutral	-1,99	medium_impact	3,31	neutral	0,68	neutral	0,52	deleterious	3,23	22,8	0,36	0,55	disease	0,56	disease	0,74	disease	0,62	disease	0,61	2	deleterious	0,98	neutral	0,12	deleterious	4	deleterious	0,57	low_impact	-1,32	medium_impact	-0,65	medium_impact	1,96	0,87	0,9	12,87	13,9	P	0,49	N	0,68	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6665	6665	C	A	MI.3504	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	762	254	I	M	atC/atA	7,53	1	0,01	possibly_damaging	0,8	deleterious	0,03	neutral	2,66	neutral	-1,4	neutral	-1,99	medium_impact	3,31	neutral	0,68	neutral	0,52	deleterious	3,63	23,2	0,36	0,55	disease	0,56	disease	0,74	disease	0,62	disease	0,61	2	deleterious	0,98	neutral	0,12	deleterious	4	deleterious	0,57	low_impact	-1,32	medium_impact	-0,65	medium_impact	1,96	0,87	0,9	12,87	13,9	P	0,5	N	0,68	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6666	6666	T	C	MI.3505	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	763	255	S	P	Tcc/Ccc	-4,73	0	0	probably_damaging	1	deleterious	0	neutral	2,69	deleterious	-3,8	deleterious	-3,58	high_impact	4,94	damaging	0,41	damaging	0,15	deleterious	3,94	23,5	0,15	0,55	disease	0,72	disease	0,88	disease	0,8	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,46	0,7	0,9	4,87	8,06	P	0,7	P	0,91	polymorphism	0,94	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6666	6666	T	A	MI.3506	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	763	255	S	T	Tcc/Acc	-4,73	0	0	probably_damaging	0,99	deleterious	0	neutral	2,72	neutral	-2,72	neutral	-2,14	high_impact	3,51	damaging	0,5	damaging	0,15	deleterious	3,75	23,3	0,21	0,55	neutral	0,48	disease	0,79	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	2,14	0,81	0,9	4,87	8,06	N	0,36	N	0,43	polymorphism	0,99	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6666	6666	T	G	MI.3507	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	763	255	S	A	Tcc/Gcc	-4,73	0	0	probably_damaging	0,99	deleterious	0	neutral	2,73	neutral	-2,32	neutral	-2,14	high_impact	4,94	neutral	0,6	damaging	0,17	deleterious	3,68	23,3	0,24	0,55	neutral	0,37	disease	0,72	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	3,46	0,77	0,9	4,87	8,06	P	0,67	P	0,35	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6667	6667	C	T	MI.3508	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	764	255	S	F	tCc/tTc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-2,86	deleterious	-4,28	high_impact	4,94	damaging	0,39	damaging	0,12	deleterious	4,25	23,9	0,12	0,55	disease	0,81	disease	0,93	disease	0,72	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,46	0,47	0,9	4,87	8,06	P	0,79	P	0,98	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6667	6667	C	G	MI.3509	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	764	255	S	C	tCc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-4,83	deleterious	-3,58	high_impact	5,29	damaging	0,48	damaging	0,11	deleterious	3,61	23,2	0,17	0,55	disease	0,89	disease	0,86	disease	0,72	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,63	0,9	4,87	8,06	P	0,71	P	0,85	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8692	8692	C	A	MI.351	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	166	56	Q	K	Caa/Aaa	1,52	1	0	probably_damaging	0,97	neutral	0,13	neutral	4,34	neutral	-0,95	deleterious	-3,63	medium_impact	3,15	neutral	0,71	damaging	0,14	deleterious	3,93	23,5	0,53	0,65	disease	0,63	disease	0,82	disease	0,62	disease	0,66	3	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,81	low_impact	-2,19	medium_impact	-0,18	medium_impact	1,6	0,44	0,9	50	8,48	N	0,37	N	0,98	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6667	6667	C	A	MI.3510	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	764	255	S	Y	tCc/tAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,98	neutral	-0,08	deleterious	-4,28	high_impact	5,29	damaging	0,51	damaging	0,12	deleterious	4,07	23,7	0,12	0,55	disease	0,53	disease	0,92	disease	0,74	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,72	0,9	4,87	8,06	P	0,72	P	0,92	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6669	6669	C	G	MI.3511	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	766	256	H	D	Cat/Gat	-14,45	0	0	probably_damaging	1	deleterious	0	neutral	2,8	neutral	-0,07	deleterious	-6,25	high_impact	4,15	damaging	0,5	damaging	0,03	deleterious	3,91	23,5	0,22	0,55	neutral	0,35	disease	0,93	disease	0,8	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,73	0,73	0,9	3,9	8,83	N	0,4	N	0,97	polymorphism	0,82	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6669	6669	C	A	MI.3512	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	766	256	H	N	Cat/Aat	-14,45	0	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-0,58	deleterious	-4,85	high_impact	4,5	damaging	0,54	damaging	0,04	deleterious	4,05	23,7	0,42	0,55	neutral	0,35	disease	0,91	disease	0,72	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,68	0,9	3,9	8,83	N	0,41	N	0,86	polymorphism	0,94	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6669	6669	C	T	MI.3513	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	766	256	H	Y	Cat/Tat	-14,45	0	0	probably_damaging	1	deleterious	0	neutral	2,95	neutral	1,64	deleterious	-4,18	high_impact	4,15	damaging	0,54	damaging	0,03	deleterious	3,8	23,4	0,38	0,55	disease	0,59	disease	0,93	disease	0,72	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,73	0,53	0,9	3,9	8,83	N	0,33	N	0,72	polymorphism	0,93	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6670	6670	A	T	MI.3514	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	767	256	H	L	cAt/cTt	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,83	neutral	0,38	deleterious	-7,67	high_impact	3,73	neutral	0,66	damaging	0,03	deleterious	3,9	23,5	0,25	0,55	neutral	0,4	disease	0,95	disease	0,72	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,35	0,46	0,9	3,9	8,83	P	0,5	N	0,92	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6670	6670	A	G	MI.3515	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	767	256	H	R	cAt/cGt	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,79	neutral	-0,48	deleterious	-5,54	high_impact	4,36	damaging	0,57	damaging	0,04	deleterious	3,04	22,4	0,41	0,55	neutral	0,34	disease	0,94	disease	0,72	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,93	0,54	0,9	3,9	8,83	N	0,47	N	0,85	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6670	6670	A	C	MI.3516	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	767	256	H	P	cAt/cCt	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-1,81	deleterious	-6,97	high_impact	5,04	damaging	0,48	damaging	0,05	deleterious	3,29	22,8	0,19	0,55	disease	0,54	disease	0,94	disease	0,82	disease	0,9	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,5	0,9	3,9	8,83	P	0,67	P	0,9	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6671	6671	T	A	MI.3517	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	768	256	H	Q	caT/caA	8,69	1	0,02	probably_damaging	1	neutral	0,19	neutral	2,8	neutral	-0,12	deleterious	-5,48	low_impact	1,81	neutral	0,63	damaging	0,04	deleterious	3,62	23,2	0,46	0,55	neutral	0,26	disease	0,76	disease	0,56	neutral	0,49	0	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,78	low_impact	-3,58	medium_impact	-0,16	medium_impact	0,57	0,79	0,9	3,9	8,83	N	0,4	N	0,83	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6671	6671	T	G	MI.3518	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	768	256	H	Q	caT/caG	8,69	1	0,02	probably_damaging	1	neutral	0,19	neutral	2,8	neutral	-0,12	deleterious	-5,48	low_impact	1,81	neutral	0,63	damaging	0,04	deleterious	3,53	23,1	0,46	0,55	neutral	0,26	disease	0,76	disease	0,56	neutral	0,49	0	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,78	low_impact	-3,58	medium_impact	-0,16	medium_impact	0,57	0,79	0,9	3,9	8,83	N	0,39	N	0,83	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6672	6672	A	T	MI.3519	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	769	257	I	F	Att/Ttt	-3,11	0	0	possibly_damaging	0,52	deleterious	0	neutral	2,55	deleterious	-3,24	deleterious	-2,74	high_impact	4,38	damaging	0,58	neutral	0,34	deleterious	3,16	22,6	0,27	0,55	disease	0,64	disease	0,88	disease	0,63	disease	0,72	4	deleterious	1	neutral	0,24	deleterious	5	deleterious	0,59	medium_impact	-0,79	low_impact	-1,48	high_impact	2,95	0,82	0,9	9,75	22,27	N	0,42	N	0,72	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8692	8692	C	G	MI.352	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	166	56	Q	E	Caa/Gaa	1,52	1	0	probably_damaging	0,94	neutral	0,79	neutral	4,38	neutral	-0,11	deleterious	-2,72	low_impact	1,51	neutral	0,74	damaging	0,15	deleterious	2,93	22	0,57	0,65	neutral	0,49	neutral	0,5	neutral	0,38	neutral	0,44	1	neutral	0,93	neutral	0,43	neutral	-2	deleterious	0,75	low_impact	-1,89	medium_impact	0,62	medium_impact	0,2	0,65	0,9	50	8,48	N	0,3	N	0,94	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6672	6672	A	G	MI.3520	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	769	257	I	V	Att/Gtt	-3,11	0	0	benign	0,06	neutral	0,27	neutral	2,72	neutral	-0,55	neutral	-0,37	low_impact	1,44	neutral	0,73	neutral	0,93	neutral	-0,61	0,12	0,6	0,65	neutral	0,24	neutral	0,32	neutral	0,31	neutral	0,42	2	neutral	0,71	deleterious	0,61	neutral	-6	neutral	0,16	medium_impact	0,37	medium_impact	-0,05	medium_impact	0,23	0,72	0,9	9,75	22,27	N	0,51	P	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6672	6672	A	C	MI.3521	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	769	257	I	L	Att/Ctt	-3,11	0	0	benign	0,01	neutral	0,08	neutral	2,76	neutral	-0,71	neutral	-1,28	medium_impact	3,46	neutral	0,66	neutral	0,38	neutral	1,55	13,6	0,31	0,55	neutral	0,35	disease	0,76	neutral	0,47	disease	0,53	1	neutral	0,92	deleterious	0,54	neutral	-3	neutral	0,23	medium_impact	1,12	medium_impact	-0,4	high_impact	2,1	0,78	0,9	9,75	22,27	N	0,44	N	0,23	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6673	6673	T	C	MI.3522	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	770	257	I	T	aTt/aCt	2,67	0,98	0	possibly_damaging	0,73	deleterious	0,01	neutral	2,5	neutral	-2,85	deleterious	-3,08	medium_impact	2,77	neutral	0,62	neutral	0,39	deleterious	3,2	22,7	0,33	0,55	disease	0,54	disease	0,83	neutral	0,43	disease	0,54	1	deleterious	0,99	neutral	0,14	deleterious	4	deleterious	0,68	low_impact	-1,16	medium_impact	-0,92	medium_impact	1,46	0,63	0,9	9,75	22,27	N	0,43	N	0,7	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6673	6673	T	G	MI.3523	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	770	257	I	S	aTt/aGt	2,67	0,98	0	possibly_damaging	0,86	neutral	0,13	neutral	2,5	deleterious	-3,4	deleterious	-3,94	high_impact	3,9	neutral	0,65	neutral	0,39	deleterious	4,19	23,8	0,21	0,55	disease	0,51	disease	0,9	disease	0,61	disease	0,68	4	neutral	0,94	neutral	0,14	deleterious	1	deleterious	0,79	low_impact	-1,5	medium_impact	-0,27	high_impact	2,5	0,57	0,9	9,75	22,27	P	0,54	P	0,61	polymorphism	0,98	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6673	6673	T	A	MI.3524	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	770	257	I	N	aTt/aAt	2,67	0,98	0	probably_damaging	0,96	deleterious	0	neutral	2,47	deleterious	-4,73	deleterious	-4,67	high_impact	4,59	neutral	0,66	neutral	0,39	deleterious	4,28	24	0,23	0,55	disease	0,79	disease	0,91	disease	0,64	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-2,06	low_impact	-1,48	high_impact	3,14	0,69	0,9	9,75	22,27	P	0,54	P	0,71	polymorphism	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6674	6674	T	G	MI.3525	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	771	257	I	M	atT/atG	7,53	1	0	possibly_damaging	0,63	neutral	0,06	neutral	2,53	neutral	-2,75	neutral	-1,75	medium_impact	2,45	neutral	0,69	neutral	0,44	deleterious	3,07	22,4	0,4	0,55	disease	0,51	disease	0,67	neutral	0,32	neutral	0,46	1	neutral	0,94	neutral	0,22	NA	0	deleterious	0,55	medium_impact	-0,97	medium_impact	-0,47	medium_impact	1,16	0,81	0,9	9,75	22,27	P	0,55	P	0,51	polymorphism	0,98	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6674	6674	T	A	MI.3526	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	771	257	I	M	atT/atA	7,53	1	0	possibly_damaging	0,63	neutral	0,06	neutral	2,53	neutral	-2,75	neutral	-1,75	medium_impact	2,45	neutral	0,69	neutral	0,44	deleterious	3,41	23	0,4	0,55	disease	0,51	disease	0,67	neutral	0,32	neutral	0,46	1	neutral	0,94	neutral	0,22	NA	0	deleterious	0,55	medium_impact	-0,97	medium_impact	-0,47	medium_impact	1,16	0,81	0,9	9,75	22,27	P	0,55	P	0,51	polymorphism	0,98	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6675	6675	G	A	MI.3527	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	772	258	V	M	Gta/Ata	-5,19	0	0	probably_damaging	1	deleterious	0	neutral	2,6	neutral	-2,22	neutral	-1,57	medium_impact	2,27	neutral	0,62	damaging	0,15	deleterious	3,66	23,2	0,45	0,55	disease	0,55	disease	0,59	neutral	0,47	neutral	0,5	0	deleterious	1	neutral	0	deleterious	5	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	medium_impact	1	0,96	1	5,85	8,37	N	0,29	N	0,82	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6675	6675	G	C	MI.3528	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	772	258	V	L	Gta/Cta	-5,19	0	0	probably_damaging	0,97	neutral	0,19	neutral	2,86	neutral	0,27	neutral	-1,05	low_impact	1,15	damaging	0,59	damaging	0,12	deleterious	3,42	23	0,32	0,55	neutral	0,24	disease	0,58	neutral	0,28	neutral	0,45	1	deleterious	0,98	neutral	0,11	neutral	-2	deleterious	0,7	low_impact	-2,18	medium_impact	-0,16	medium_impact	-0,04	0,75	0,9	5,85	8,37	N	0,34	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6675	6675	G	T	MI.3529	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	772	258	V	L	Gta/Tta	-5,19	0	0	probably_damaging	0,97	neutral	0,19	neutral	2,86	neutral	0,27	neutral	-1,05	low_impact	1,15	damaging	0,59	damaging	0,12	deleterious	3,57	23,1	0,32	0,55	neutral	0,24	disease	0,58	neutral	0,28	neutral	0,45	1	deleterious	0,98	neutral	0,11	neutral	-2	deleterious	0,7	low_impact	-2,18	medium_impact	-0,16	medium_impact	-0,04	0,75	0,9	5,85	8,37	N	0,34	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8693	8693	A	T	MI.353	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	167	56	Q	L	cAa/cTa	7,3	1	0	probably_damaging	0,97	neutral	0,3	neutral	4,52	neutral	1,17	deleterious	-5,83	low_impact	1,7	neutral	0,72	damaging	0,13	deleterious	3,39	23	0,34	0,65	disease	0,58	disease	0,81	neutral	0,5	disease	0,62	2	neutral	0,98	neutral	0,17	neutral	-2	deleterious	0,8	low_impact	-2,19	medium_impact	0,08	medium_impact	0,36	0,23	0,9	50	8,48	N	0,41	N	0,99	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6676	6676	T	C	MI.3530	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	773	258	V	A	gTa/gCa	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	2,64	neutral	-1,48	deleterious	-2,79	medium_impact	3,32	neutral	0,62	damaging	0,16	deleterious	3,5	23,1	0,32	0,55	neutral	0,38	disease	0,55	disease	0,58	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,97	0,65	0,9	5,85	8,37	P	0,49	N	0,47	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6676	6676	T	G	MI.3531	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	773	258	V	G	gTa/gGa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-3,86	deleterious	-4,92	high_impact	4,01	damaging	0,57	damaging	0,17	deleterious	3,71	23,3	0,17	0,55	disease	0,69	disease	0,74	disease	0,59	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,6	0,57	0,9	5,85	8,37	N	0,46	N	0,71	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6676	6676	T	A	MI.3532	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	773	258	V	E	gTa/gAa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-4,12	deleterious	-4,22	high_impact	4,01	damaging	0,58	damaging	0,15	deleterious	4,54	24,3	0,12	0,55	disease	0,7	disease	0,86	disease	0,71	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,6	0,55	0,9	5,85	8,37	P	0,51	P	0,84	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6678	6678	A	C	MI.3533	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	775	259	T	P	Act/Cct	-11,9	0	0	possibly_damaging	0,85	neutral	0,27	neutral	3,28	neutral	2,45	neutral	-1,56	neutral_impact	0,78	damaging	0,44	damaging	0,06	deleterious	3,33	22,9	0,17	0,55	neutral	0,22	disease	0,75	neutral	0,46	disease	0,52	0	neutral	0,89	neutral	0,21	neutral	-3	deleterious	0,7	low_impact	-1,47	medium_impact	-0,05	medium_impact	-0,38	0,76	0,9	9,55	11,35	N	0,31	N	0,92	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6678	6678	A	G	MI.3534	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	775	259	T	A	Act/Gct	-11,9	0	0	benign	0,02	neutral	1	neutral	3,04	neutral	0,64	neutral	0,14	neutral_impact	0,26	neutral	0,68	neutral	0,46	neutral	-0,41	0,36	0,53	0,6	neutral	0,18	neutral	0,26	neutral	0,14	neutral	0,43	1	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,14	medium_impact	0,83	high_impact	1,86	medium_impact	-0,86	0,63	0,9	9,55	11,35	N	0,39	N	0,69	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6678	6678	A	T	MI.3535	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	775	259	T	S	Act/Tct	-11,9	0	0	benign	0,28	neutral	0,91	neutral	3,05	neutral	0,79	neutral	0,99	neutral_impact	-1,3	neutral	0,61	damaging	0,23	neutral	-1,15	0,01	0,42	0,55	neutral	0,22	neutral	0,07	neutral	0,1	neutral	0,22	6	neutral	0,17	deleterious	0,82	neutral	-6	neutral	0,22	medium_impact	-0,37	medium_impact	0,75	low_impact	-2,3	0,8	0,9	9,55	11,35	N	0,37	N	0,79	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6679	6679	C	T	MI.3536	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	776	259	T	I	aCt/aTt	1,29	0,85	0	possibly_damaging	0,82	neutral	0,12	neutral	3,01	neutral	0,16	neutral	-1,67	neutral_impact	0,22	damaging	0,51	damaging	0,06	deleterious	3,63	23,2	0,41	0,55	neutral	0,33	disease	0,51	neutral	0,16	neutral	0,41	2	neutral	0,93	neutral	0,15	neutral	-3	deleterious	0,63	low_impact	-1,38	medium_impact	-0,29	medium_impact	-0,9	0,78	0,9	9,55	11,35	N	0,39	N	0,92	polymorphism	0,91	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6679	6679	C	G	MI.3537	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	776	259	T	S	aCt/aGt	1,29	0,85	0	benign	0,28	neutral	0,91	neutral	3,05	neutral	0,79	neutral	0,99	neutral_impact	-1,3	neutral	0,61	damaging	0,23	neutral	-1,01	0,02	0,42	0,55	neutral	0,22	neutral	0,07	neutral	0,1	neutral	0,22	6	neutral	0,17	deleterious	0,82	neutral	-6	neutral	0,22	medium_impact	-0,37	medium_impact	0,75	low_impact	-2,3	0,8	0,9	9,55	11,35	N	0,29	N	0,79	polymorphism	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6679	6679	C	A	MI.3538	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	776	259	T	N	aCt/aAt	1,29	0,85	0	possibly_damaging	0,85	neutral	0,14	neutral	2,96	neutral	-1,23	neutral	-0,72	medium_impact	2,02	damaging	0,51	damaging	0,09	deleterious	2,41	18,86	0,49	0,55	neutral	0,46	disease	0,66	neutral	0,28	neutral	0,49	0	neutral	0,93	neutral	0,15	NA	0	deleterious	0,65	low_impact	-1,47	medium_impact	-0,25	medium_impact	0,77	0,82	0,9	9,55	11,35	N	0,36	N	0,8	polymorphism	0,91	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6681	6681	T	G	MI.3539	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	778	260	Y	D	Tac/Gac	-20	0	0	possibly_damaging	0,85	deleterious	0,04	neutral	2,97	neutral	0,61	neutral	-0,91	low_impact	1,23	neutral	0,66	neutral	0,36	deleterious	2,78	21,3	0,41	0,55	disease	0,53	disease	0,74	neutral	0,45	disease	0,53	1	neutral	0,98	neutral	0,1	deleterious	1	deleterious	0,76	low_impact	-1,47	medium_impact	-0,58	medium_impact	0,04	0,48	0,9	11,5	20,69	N	0,34	N	0,84	polymorphism	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8693	8693	A	C	MI.354	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	167	56	Q	P	cAa/cCa	7,3	1	0	probably_damaging	0,98	neutral	0,07	neutral	4,31	neutral	-2,43	deleterious	-5,53	high_impact	3,84	neutral	0,64	damaging	0,15	deleterious	2,97	22,1	0,18	0,65	disease	0,86	disease	0,88	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,89	low_impact	-2,36	medium_impact	-0,34	high_impact	2,19	0,39	0,9	50	8,48	P	0,54	P	0,97	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6681	6681	T	A	MI.3540	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	778	260	Y	N	Tac/Aac	-20	0	0	possibly_damaging	0,8	neutral	0,18	neutral	3	neutral	1,36	neutral	-0,21	neutral_impact	-0,91	neutral	0,69	neutral	0,42	deleterious	2,59	20,1	0,36	0,55	neutral	0,45	disease	0,51	neutral	0,27	neutral	0,43	1	neutral	0,89	neutral	0,19	neutral	-3	deleterious	0,65	low_impact	-1,32	medium_impact	-0,17	low_impact	-1,94	0,36	0,9	11,5	20,69	N	0,4	N	0,78	polymorphism	0,96	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6681	6681	T	C	MI.3541	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	778	260	Y	H	Tac/Cac	-20	0	0	benign	0,06	neutral	0,28	neutral	2,99	neutral	0,02	neutral	0,94	neutral_impact	-1,27	neutral	0,69	neutral	0,81	neutral	-0,68	0,08	0,64	0,7	neutral	0,33	neutral	0,26	neutral	0,19	neutral	0,44	1	neutral	0,69	deleterious	0,61	neutral	-6	neutral	0,2	medium_impact	0,37	medium_impact	-0,04	low_impact	-2,27	0,49	0,9	11,5	20,69	N	0,55	P	0,02	polymorphism	1	0,01	rs879180101	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6682	6682	A	G	MI.3542	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	779	260	Y	C	tAc/tGc	4,76	1	0	probably_damaging	0,98	deleterious	0,04	neutral	2,96	neutral	-0,95	neutral	-2,17	low_impact	1,46	neutral	0,64	neutral	0,28	deleterious	2,4	18,83	0,39	0,55	disease	0,56	disease	0,75	neutral	0,28	disease	0,54	1	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,78	low_impact	-2,35	medium_impact	-0,58	medium_impact	0,25	0,17	0,9	11,5	20,69	N	0,41	N	0,69	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6682	6682	A	T	MI.3543	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	779	260	Y	F	tAc/tTc	4,76	1	0	possibly_damaging	0,55	neutral	0,37	neutral	3,01	neutral	-0,02	neutral	-1,07	neutral_impact	-0,08	neutral	0,71	neutral	0,75	neutral	1,15	11,46	0,42	0,55	neutral	0,32	neutral	0,44	neutral	0,17	neutral	0,46	1	neutral	0,63	neutral	0,41	neutral	-3	deleterious	0,51	medium_impact	-0,84	medium_impact	0,06	low_impact	-1,17	0,41	0,9	11,5	20,69	P	0,56	P	0,42	disease_causing	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6682	6682	A	C	MI.3544	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	779	260	Y	S	tAc/tCc	4,76	1	0	possibly_damaging	0,8	neutral	0,24	neutral	3,02	neutral	1,28	neutral	-0,39	neutral_impact	-0,7	neutral	0,68	neutral	0,42	deleterious	2,06	16,57	0,3	0,55	neutral	0,23	neutral	0,49	neutral	0,27	neutral	0,41	2	neutral	0,86	neutral	0,22	neutral	-3	deleterious	0,64	low_impact	-1,32	medium_impact	-0,09	low_impact	-1,75	0,34	0,9	11,5	20,69	N	0,51	P	0,75	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6684	6684	T	C	MI.3545	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	781	261	Y	H	Tac/Cac	-6,35	0	0	benign	0,06	neutral	0,13	neutral	2,76	neutral	-1,69	neutral	-0,2	neutral_impact	0,68	damaging	0,54	damaging	0,09	deleterious	0,16	4,3	0,62	0,65	neutral	0,38	disease	0,56	neutral	0,42	neutral	0,45	1	neutral	0,86	deleterious	0,54	neutral	-6	neutral	0,27	medium_impact	0,37	medium_impact	-0,27	medium_impact	-0,47	0,31	0,9	1,75	9,15	N	0,36	N	0,61	polymorphism	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6684	6684	T	A	MI.3546	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	781	261	Y	N	Tac/Aac	-6,35	0	0	possibly_damaging	0,79	neutral	0,1	neutral	2,75	neutral	-1,7	neutral	-0,93	low_impact	1,11	damaging	0,55	damaging	0,07	deleterious	2,76	21,2	0,45	0,55	neutral	0,25	disease	0,78	neutral	0,44	disease	0,54	1	neutral	0,93	neutral	0,16	neutral	-3	deleterious	0,68	low_impact	-1,3	medium_impact	-0,34	medium_impact	-0,07	0,4	0,9	1,75	9,15	N	0,28	N	0,94	polymorphism	0,88	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6684	6684	T	G	MI.3547	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	781	261	Y	D	Tac/Gac	-6,35	0	0	possibly_damaging	0,84	deleterious	0,04	neutral	2,74	deleterious	-3	neutral	-0,87	medium_impact	2,17	damaging	0,53	damaging	0,05	deleterious	2,77	21,2	0,42	0,55	neutral	0,45	disease	0,85	disease	0,67	disease	0,74	5	neutral	0,98	neutral	0,1	deleterious	4	deleterious	0,79	low_impact	-1,43	medium_impact	-0,58	medium_impact	0,91	0,43	0,9	1,75	9,15	N	0,28	N	0,98	polymorphism	0,91	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6685	6685	A	T	MI.3548	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	782	261	Y	F	tAc/tTc	5,68	1	0	possibly_damaging	0,54	neutral	0,32	neutral	2,98	neutral	1,76	neutral	-1,27	neutral_impact	0,07	damaging	0,57	damaging	0,05	neutral	1,49	13,27	0,48	0,55	neutral	0,22	neutral	0,45	neutral	0,28	neutral	0,44	1	neutral	0,67	neutral	0,39	neutral	-3	deleterious	0,55	medium_impact	-0,82	medium_impact	0,01	low_impact	-1,03	0,29	0,9	1,75	9,15	P	0,52	P	0,5	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6685	6685	A	G	MI.3549	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	782	261	Y	C	tAc/tGc	5,68	1	0	probably_damaging	0,98	deleterious	0,03	neutral	2,75	neutral	-2,17	deleterious	-2,71	medium_impact	2,35	damaging	0,52	damaging	0,05	deleterious	2,43	18,98	0,36	0,55	disease	0,62	disease	0,85	neutral	0,44	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,84	low_impact	-2,35	medium_impact	-0,65	medium_impact	1,07	0,17	0,9	1,75	9,15	N	0,41	N	0,89	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8693	8693	A	G	MI.355	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	167	56	Q	R	cAa/cGa	7,3	1	0	probably_damaging	0,97	neutral	0,12	neutral	4,35	neutral	-0,79	deleterious	-3,59	medium_impact	3,49	neutral	0,76	damaging	0,15	deleterious	3,02	22,3	0,58	0,7	disease	0,73	disease	0,84	disease	0,64	disease	0,71	4	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,86	low_impact	-2,19	medium_impact	-0,2	medium_impact	1,89	0,38	0,9	50	8,48	P	0,55	P	0,87	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6685	6685	A	C	MI.3550	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	782	261	Y	S	tAc/tCc	5,68	1	0	possibly_damaging	0,79	neutral	0,07	neutral	2,79	neutral	-0,46	neutral	-0,82	neutral_impact	0,77	damaging	0,53	damaging	0,07	deleterious	2,25	17,82	0,29	0,55	neutral	0,31	disease	0,7	disease	0,52	disease	0,53	1	neutral	0,95	neutral	0,14	neutral	-3	deleterious	0,7	low_impact	-1,3	medium_impact	-0,43	medium_impact	-0,39	0,42	0,9	1,75	9,15	N	0,49	N	0,9	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6687	6687	T	A	MI.3551	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	784	262	S	T	Tcc/Acc	-6,35	0	0	probably_damaging	0,97	neutral	0,34	neutral	2,86	neutral	-1,12	neutral	-1,13	medium_impact	2,49	neutral	0,63	damaging	0,24	deleterious	2,81	21,4	0,33	0,55	neutral	0,43	disease	0,69	neutral	0,33	neutral	0,48	1	neutral	0,98	neutral	0,19	deleterious	1	deleterious	0,74	low_impact	-2,18	medium_impact	0,03	medium_impact	1,2	0,74	0,9	3,51	10,51	N	0,35	N	0,43	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6687	6687	T	G	MI.3552	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	784	262	S	A	Tcc/Gcc	-6,35	0	0	probably_damaging	0,99	neutral	0,26	neutral	2,97	neutral	-0,16	neutral	-1,1	medium_impact	2,47	neutral	0,71	neutral	0,77	deleterious	2,43	19	0,42	0,55	neutral	0,23	disease	0,53	neutral	0,34	neutral	0,42	2	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,66	low_impact	-2,64	medium_impact	-0,06	medium_impact	1,18	0,7	0,9	3,51	10,51	N	0,45	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6687	6687	T	C	MI.3553	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	784	262	S	P	Tcc/Ccc	-6,35	0	0	probably_damaging	1	deleterious	0	neutral	2,75	deleterious	-3,52	deleterious	-2,71	high_impact	4,68	damaging	0,53	damaging	0,12	deleterious	4,09	23,7	0,25	0,55	disease	0,71	disease	0,89	disease	0,61	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,22	0,5	0,9	3,51	10,51	N	0,51	P	0,91	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6688	6688	C	T	MI.3554	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	785	262	S	F	tCc/tTc	0,36	0,29	0	probably_damaging	1	deleterious	0	neutral	2,77	neutral	-2,6	deleterious	-3,16	high_impact	4,47	damaging	0,56	damaging	0,11	deleterious	4,3	24	0,24	0,55	disease	0,6	disease	0,91	disease	0,65	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,03	0,34	0,9	3,51	10,51	N	0,4	N	0,98	polymorphism	0,97	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6688	6688	C	G	MI.3555	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	785	262	S	C	tCc/tGc	0,36	0,29	0	probably_damaging	1	deleterious	0,01	neutral	2,74	deleterious	-3,86	neutral	-2,42	medium_impact	3,03	neutral	0,6	damaging	0,15	deleterious	3,62	23,2	0,34	0,55	disease	0,76	disease	0,85	disease	0,52	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,7	0,7	0,9	3,51	10,51	N	0,27	N	0,85	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6688	6688	C	A	MI.3556	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	785	262	S	Y	tCc/tAc	0,36	0,29	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-2,85	deleterious	-3,19	high_impact	3,98	neutral	0,61	damaging	0,11	deleterious	4,11	23,7	0,25	0,55	disease	0,53	disease	0,91	disease	0,66	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,58	0,59	0,9	3,51	10,51	N	0,3	N	0,92	polymorphism	0,98	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6690	6690	G	T	MI.3557	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	787	263	G	W	Gga/Tga	-5,89	0	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-6,32	deleterious	-4,96	high_impact	4,8	neutral	0,65	damaging	0,08	deleterious	4,46	24,2	0,19	0,55	disease	0,9	disease	0,92	disease	0,63	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,33	0,46	0,9	8,19	30,49	P	0,56	P	0,83	polymorphism	0,61	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6690	6690	G	C	MI.3558	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	787	263	G	R	Gga/Cga	-5,89	0	0	probably_damaging	0,94	deleterious	0	neutral	2,75	neutral	-1,55	deleterious	-4,62	medium_impact	3,02	damaging	0,57	damaging	0,1	deleterious	4	23,6	0,26	0,55	disease	0,58	disease	0,91	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,86	low_impact	-1,88	low_impact	-1,48	medium_impact	1,69	0,71	0,9	8,19	30,49	N	0,23	N	0,95	polymorphism	0,72	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6691	6691	G	C	MI.3559	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	788	263	G	A	gGa/gCa	6,14	1	0	possibly_damaging	0,55	neutral	0,09	neutral	2,66	neutral	-2,87	deleterious	-3,26	medium_impact	2,81	neutral	0,67	damaging	0,21	deleterious	2,08	16,7	0,26	0,55	neutral	0,32	disease	0,7	neutral	0,4	disease	0,52	0	neutral	0,9	neutral	0,27	NA	0	deleterious	0,56	medium_impact	-0,84	medium_impact	-0,37	medium_impact	1,5	0,55	0,9	8,19	30,49	P	0,51	P	0,64	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8694	8694	A	C	MI.356	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	168	56	Q	H	caA/caC	8,69	1	0	probably_damaging	1	neutral	0,21	neutral	4,31	neutral	-2,27	deleterious	-4,58	medium_impact	2	neutral	0,82	damaging	0,18	deleterious	3,2	22,7	0,55	0,65	disease	0,84	disease	0,68	neutral	0,42	disease	0,63	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	-0,03	medium_impact	0,62	0,59	0,9	50	8,48	N	0,49	N	0,95	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6691	6691	G	T	MI.3560	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	788	263	G	V	gGa/gTa	6,14	1	0	probably_damaging	0,97	deleterious	0,01	neutral	2,63	deleterious	-3,93	deleterious	-5,29	medium_impact	3,45	neutral	0,61	damaging	0,09	deleterious	3,75	23,3	0,22	0,55	disease	0,51	disease	0,92	disease	0,56	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,85	low_impact	-2,18	medium_impact	-0,92	high_impact	2,09	0,44	0,9	8,19	30,49	N	0,4	N	0,93	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6691	6691	G	A	MI.3561	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	788	263	G	E	gGa/gAa	6,14	1	0	possibly_damaging	0,88	deleterious	0,01	neutral	2,71	neutral	-2,05	deleterious	-4,6	high_impact	4,46	neutral	0,63	damaging	0,09	deleterious	3,89	23,5	0,22	0,55	disease	0,5	disease	0,9	disease	0,62	disease	0,75	5	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,82	low_impact	-1,57	medium_impact	-0,92	high_impact	3,02	0,5	0,9	8,19	30,49	P	0,49	N	0,93	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6693	6693	A	G	MI.3562	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	790	264	K	E	Aaa/Gaa	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,64	neutral	-2,97	deleterious	-2,86	high_impact	4,58	damaging	0,53	damaging	0,18	deleterious	4,05	23,7	0,39	0,55	neutral	0,32	disease	0,91	disease	0,69	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,13	0,54	0,9	3,12	6,71	N	0,44	N	0,75	polymorphism	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6693	6693	A	C	MI.3563	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	790	264	K	Q	Aaa/Caa	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,64	deleterious	-3,09	deleterious	-2,86	high_impact	3,81	neutral	0,64	damaging	0,13	deleterious	3,52	23,1	0,4	0,55	neutral	0,43	disease	0,85	disease	0,52	disease	0,62	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,42	0,7	0,9	3,12	6,71	N	0,31	N	0,64	polymorphism	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6694	6694	A	C	MI.3564	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	791	264	K	T	aAa/aCa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,64	neutral	-2,92	deleterious	-4,26	high_impact	4,43	neutral	0,63	damaging	0,15	deleterious	3,44	23	0,25	0,55	neutral	0,41	disease	0,91	disease	0,66	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,99	0,56	0,9	3,12	6,71	N	0,48	N	0,76	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6694	6694	A	T	MI.3565	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	791	264	K	M	aAa/aTa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-4,93	deleterious	-4,28	high_impact	4,78	neutral	0,67	damaging	0,14	deleterious	3,7	23,3	0,18	0,55	disease	0,76	disease	0,89	disease	0,63	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,32	0,54	0,9	3,12	6,71	P	0,7	P	0,89	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6695	6695	A	T	MI.3566	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	792	264	K	N	aaA/aaT	8,69	1	0	probably_damaging	1	neutral	0,06	neutral	2,64	neutral	-2,93	deleterious	-3,56	medium_impact	3,06	damaging	0,55	damaging	0,11	deleterious	3,76	23,3	0,45	0,55	neutral	0,45	disease	0,87	disease	0,55	neutral	0,5	0	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,82	low_impact	-3,58	medium_impact	-0,47	medium_impact	1,73	0,55	0,9	3,12	6,71	P	0,5	N	0,76	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6695	6695	A	C	MI.3567	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	792	264	K	N	aaA/aaC	8,69	1	0	probably_damaging	1	neutral	0,06	neutral	2,64	neutral	-2,93	deleterious	-3,56	medium_impact	3,06	damaging	0,55	damaging	0,11	deleterious	3,68	23,3	0,45	0,55	neutral	0,45	disease	0,87	disease	0,55	neutral	0,5	0	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,82	low_impact	-3,58	medium_impact	-0,47	medium_impact	1,73	0,55	0,9	3,12	6,71	P	0,48	N	0,76	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6696	6696	A	C	MI.3568	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	793	265	K	Q	Aaa/Caa	4,06	1	0	benign	0	deleterious	0,03	neutral	2,61	neutral	-2,71	neutral	-1,81	high_impact	3,75	neutral	0,64	neutral	0,68	deleterious	3,16	22,6	0,49	0,55	disease	0,72	disease	0,84	neutral	0,47	disease	0,65	3	neutral	0,97	deleterious	0,52	deleterious	2	neutral	0,33	high_impact	2,07	medium_impact	-0,65	high_impact	2,36	0,79	0,9	2,73	7,44	P	0,54	P	0,55	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6696	6696	A	G	MI.3569	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	793	265	K	E	Aaa/Gaa	4,06	1	0	benign	0,04	deleterious	0,03	neutral	2,65	neutral	-2,33	neutral	-2,03	medium_impact	2,77	damaging	0,59	neutral	0,78	deleterious	3,7	23,3	0,4	0,55	disease	0,78	disease	0,91	neutral	0,42	disease	0,65	3	neutral	0,97	deleterious	0,5	deleterious	1	neutral	0,41	medium_impact	0,54	medium_impact	-0,65	medium_impact	1,46	0,78	0,9	2,73	7,44	N	0,49	N	0,07	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8694	8694	A	T	MI.357	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	168	56	Q	H	caA/caT	8,69	1	0	probably_damaging	1	neutral	0,21	neutral	4,31	neutral	-2,27	deleterious	-4,58	medium_impact	2	neutral	0,82	damaging	0,18	deleterious	3,3	22,9	0,55	0,65	disease	0,84	disease	0,68	neutral	0,42	disease	0,63	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	-0,03	medium_impact	0,62	0,59	0,9	50	8,48	N	0,49	N	0,95	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6697	6697	A	T	MI.3570	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	794	265	K	M	aAa/aTa	7,07	1	0	possibly_damaging	0,64	deleterious	0,01	neutral	2,54	deleterious	-4,67	deleterious	-2,91	medium_impact	3,46	neutral	0,65	neutral	0,65	deleterious	3,72	23,3	0,24	0,55	disease	0,93	disease	0,86	neutral	0,47	disease	0,75	5	deleterious	0,99	neutral	0,19	deleterious	4	deleterious	0,66	medium_impact	-0,99	medium_impact	-0,92	high_impact	2,1	0,61	0,9	2,73	7,44	P	0,49	N	0,7	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6697	6697	A	C	MI.3571	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	794	265	K	T	aAa/aCa	7,07	1	0	benign	0,27	deleterious	0,01	neutral	2,6	deleterious	-3,1	deleterious	-2,86	high_impact	3,54	neutral	0,63	neutral	0,59	deleterious	3,43	23	0,34	0,55	disease	0,67	disease	0,9	disease	0,59	disease	0,65	3	deleterious	0,99	neutral	0,37	deleterious	2	deleterious	0,52	medium_impact	-0,35	medium_impact	-0,92	high_impact	2,17	0,77	0,9	2,73	7,44	P	0,51	P	0,59	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6698	6698	A	C	MI.3572	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	795	265	K	N	aaA/aaC	5,68	1	0	benign	0,21	neutral	0,07	neutral	2,62	deleterious	-3,16	neutral	-2,26	medium_impact	2	damaging	0,59	neutral	0,65	deleterious	2,66	20,6	0,61	0,65	disease	0,82	disease	0,78	neutral	0,35	disease	0,6	2	neutral	0,92	neutral	0,43	neutral	-3	deleterious	0,58	medium_impact	-0,22	medium_impact	-0,43	medium_impact	0,75	0,8	0,9	2,73	7,44	P	0,52	P	0,62	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6698	6698	A	T	MI.3573	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	795	265	K	N	aaA/aaT	5,68	1	0	benign	0,21	neutral	0,07	neutral	2,62	deleterious	-3,16	neutral	-2,26	medium_impact	2	damaging	0,59	neutral	0,65	deleterious	2,8	21,4	0,61	0,65	disease	0,82	disease	0,78	neutral	0,35	disease	0,6	2	neutral	0,92	neutral	0,43	neutral	-3	deleterious	0,58	medium_impact	-0,22	medium_impact	-0,43	medium_impact	0,75	0,8	0,9	2,73	7,44	P	0,51	P	0,62	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6699	6699	G	C	MI.3574	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	796	266	E	Q	Gaa/Caa	2,67	1	0	probably_damaging	0,98	neutral	0,09	neutral	2,75	neutral	-0,77	neutral	-1,94	medium_impact	2,31	damaging	0,58	damaging	0,18	deleterious	2,25	17,86	0,43	0,55	neutral	0,3	disease	0,71	neutral	0,23	neutral	0,44	1	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,79	low_impact	-2,35	medium_impact	-0,37	medium_impact	1,03	0,7	0,9	3,51	8,4	N	0,46	N	0,66	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6699	6699	G	A	MI.3575	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	796	266	E	K	Gaa/Aaa	2,67	1	0	probably_damaging	0,97	deleterious	0	neutral	2,8	neutral	-0,03	deleterious	-2,67	high_impact	3,77	damaging	0,54	damaging	0,12	deleterious	4,51	24,3	0,32	0,55	neutral	0,27	disease	0,92	neutral	0,46	disease	0,65	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-2,18	low_impact	-1,48	high_impact	2,38	0,63	0,9	3,51	8,4	N	0,45	N	0,72	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6700	6700	A	T	MI.3576	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	797	266	E	V	gAa/gTa	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,71	neutral	-1,37	deleterious	-4,77	high_impact	3,77	damaging	0,55	damaging	0,15	deleterious	4,06	23,7	0,25	0,55	neutral	0,2	disease	0,94	neutral	0,47	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,64	low_impact	-1,48	high_impact	2,38	0,63	0,9	3,51	8,4	N	0,44	N	0,67	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6700	6700	A	G	MI.3577	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	797	266	E	G	gAa/gGa	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,71	neutral	-1,53	deleterious	-4,72	high_impact	3,65	damaging	0,48	damaging	0,19	deleterious	4,18	23,8	0,31	0,55	neutral	0,3	disease	0,87	neutral	0,5	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	2,27	0,58	0,9	3,51	8,4	P	0,49	N	0,67	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6700	6700	A	C	MI.3578	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	797	266	E	A	gAa/gCa	7,53	1	0	probably_damaging	0,98	deleterious	0,04	neutral	2,74	neutral	-0,86	deleterious	-3,98	high_impact	3,77	neutral	0,65	damaging	0,16	deleterious	3,63	23,2	0,33	0,55	neutral	0,31	disease	0,87	neutral	0,49	disease	0,64	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,8	low_impact	-2,35	medium_impact	-0,58	high_impact	2,38	0,65	0,9	3,51	8,4	P	0,48	N	0,71	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6701	6701	A	T	MI.3579	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	798	266	E	D	gaA/gaT	8,69	1	0,01	possibly_damaging	0,9	deleterious	0	neutral	2,72	neutral	-1,21	neutral	-2,04	high_impact	3,7	damaging	0,55	damaging	0,17	deleterious	3,75	23,3	0,36	0,55	neutral	0,37	disease	0,84	neutral	0,37	disease	0,64	3	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,77	low_impact	-1,65	low_impact	-1,48	high_impact	2,32	0,77	0,9	3,51	8,4	P	0,57	P	0,69	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8695	8695	A	T	MI.358	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	169	57	M	L	Atg/Ttg	3,83	1	0	possibly_damaging	0,81	neutral	0,96	neutral	4,62	neutral	2,65	neutral	-0,23	neutral_impact	-1,15	neutral	0,88	neutral	0,95	deleterious	0,37	6,36	0,53	0,65	neutral	0,45	neutral	0,18	neutral	0,25	neutral	0,28	4	neutral	0,8	deleterious	0,58	neutral	-3	deleterious	0,52	low_impact	-1,35	medium_impact	1,07	low_impact	-2,08	0,61	0,9	14,16	15,31	N	0,45	N	0,94	disease_causing	0,61	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6701	6701	A	C	MI.3580	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	798	266	E	D	gaA/gaC	8,69	1	0,01	possibly_damaging	0,9	deleterious	0	neutral	2,72	neutral	-1,21	neutral	-2,04	high_impact	3,7	damaging	0,55	damaging	0,17	deleterious	3,65	23,2	0,36	0,55	neutral	0,37	disease	0,84	neutral	0,37	disease	0,64	3	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,77	low_impact	-1,65	low_impact	-1,48	high_impact	2,32	0,77	0,9	3,51	8,4	P	0,57	P	0,69	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6702	6702	C	A	MI.3581	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	799	267	P	T	Cca/Aca	-0,1	0,34	0	probably_damaging	1	neutral	0,45	neutral	3,02	neutral	-0,14	neutral	-1,37	neutral_impact	-0,3	damaging	0,54	damaging	0,1	neutral	1,53	13,47	0,4	0,55	neutral	0,25	neutral	0,29	neutral	0,22	neutral	0,44	1	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,68	low_impact	-3,58	medium_impact	0,14	low_impact	-1,38	0,5	0,9	1,36	6,61	N	0,29	N	0,8	disease_causing	0,98	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6702	6702	C	T	MI.3582	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	799	267	P	S	Cca/Tca	-0,1	0,34	0	probably_damaging	1	neutral	0,11	neutral	3	neutral	-0,18	neutral	-2,19	neutral_impact	0,48	damaging	0,49	damaging	0,06	deleterious	2,36	18,57	0,45	0,55	neutral	0,2	neutral	0,45	neutral	0,26	neutral	0,46	1	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,69	low_impact	-3,58	medium_impact	-0,31	medium_impact	-0,66	0,28	0,9	1,36	6,61	N	0,33	N	0,85	disease_causing	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6702	6702	C	G	MI.3583	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	799	267	P	A	Cca/Gca	-0,1	0,34	0	probably_damaging	0,99	neutral	0,39	neutral	3,02	neutral	0,3	neutral	-2,3	neutral_impact	0,54	damaging	0,52	damaging	0,17	neutral	1,37	12,62	0,41	0,55	neutral	0,22	neutral	0,32	neutral	0,26	neutral	0,45	1	deleterious	0,99	neutral	0,2	neutral	-2	deleterious	0,68	low_impact	-2,64	medium_impact	0,09	medium_impact	-0,6	0,55	0,9	1,36	6,61	N	0,34	N	0,76	disease_causing	0,96	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6703	6703	C	T	MI.3584	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	800	267	P	L	cCa/cTa	5,68	1	0	probably_damaging	1	neutral	0,31	neutral	3,27	neutral	2,3	deleterious	-3,68	low_impact	1,55	damaging	0,49	damaging	0,04	deleterious	4,35	24,1	0,37	0,55	neutral	0,27	disease	0,69	neutral	0,43	disease	0,51	0	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,71	low_impact	-3,58	medium_impact	0	medium_impact	0,33	0,64	0,9	1,36	6,61	N	0,45	N	0,87	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6703	6703	C	G	MI.3585	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	800	267	P	R	cCa/cGa	5,68	1	0	probably_damaging	1	deleterious	0,03	neutral	2,99	neutral	-1,07	deleterious	-3,37	high_impact	3,63	damaging	0,51	damaging	0,05	deleterious	3,6	23,2	0,36	0,55	neutral	0,41	disease	0,79	disease	0,69	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,79	low_impact	-3,58	medium_impact	-0,65	high_impact	2,25	0,43	0,9	1,36	6,61	N	0,43	N	0,9	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6703	6703	C	A	MI.3586	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	800	267	P	Q	cCa/cAa	5,68	1	0	probably_damaging	1	deleterious	0,03	neutral	2,97	neutral	-1,75	deleterious	-2,95	medium_impact	3,29	damaging	0,51	damaging	0,04	deleterious	4,22	23,9	0,29	0,55	neutral	0,42	disease	0,55	disease	0,59	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,65	medium_impact	1,94	0,46	0,9	1,36	6,61	N	0,45	N	0,82	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6705	6705	T	C	MI.3587	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	802	268	F	L	Ttt/Ctt	-9,13	0	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-2,1	deleterious	-4,18	high_impact	4,25	damaging	0,57	neutral	0,68	deleterious	4,06	23,7	0,38	0,55	neutral	0,34	disease	0,85	disease	0,73	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,83	0,51	0,9	2,14	6,81	N	0,47	N	0,83	polymorphism	0,88	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6705	6705	T	A	MI.3588	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	802	268	F	I	Ttt/Att	-9,13	0	0	probably_damaging	1	deleterious	0	neutral	2,63	neutral	-2,81	deleterious	-4,21	high_impact	4,74	neutral	0,68	neutral	0,7	deleterious	4,42	24,2	0,2	0,55	neutral	0,28	disease	0,88	disease	0,76	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,28	0,43	0,9	2,14	6,81	P	0,66	P	0,88	polymorphism	0,89	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6705	6705	T	G	MI.3589	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	802	268	F	V	Ttt/Gtt	-9,13	0	0	probably_damaging	1	deleterious	0	neutral	2,66	neutral	-2,28	deleterious	-4,94	high_impact	4,49	neutral	0,61	neutral	0,6	deleterious	4,13	23,8	0,27	0,55	neutral	0,43	disease	0,92	disease	0,75	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,05	0,34	0,9	2,14	6,81	N	0,54	P	0,84	polymorphism	0,79	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8695	8695	A	G	MI.359	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	169	57	M	V	Atg/Gtg	3,83	1	0	possibly_damaging	0,87	neutral	0,36	neutral	4,66	neutral	2,87	neutral	-1,6	neutral_impact	-0,46	neutral	0,9	neutral	0,53	deleterious	2,38	18,71	0,55	0,65	neutral	0,49	disease	0,51	disease	0,54	disease	0,5	0	neutral	0,88	neutral	0,25	neutral	-3	deleterious	0,63	low_impact	-1,54	medium_impact	0,15	low_impact	-1,49	0,57	0,9	14,16	15,31	N	0,4	N	0,95	disease_causing	0,66	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6706	6706	T	G	MI.3590	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	803	268	F	C	tTt/tGt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-5,29	deleterious	-5,7	high_impact	5,29	neutral	0,64	neutral	0,57	deleterious	4,14	23,8	0,22	0,55	disease	0,83	disease	0,9	disease	0,77	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,25	0,9	2,14	6,81	P	0,66	P	0,91	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6706	6706	T	C	MI.3591	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	803	268	F	S	tTt/tCt	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	2,61	deleterious	-3,47	deleterious	-5,69	high_impact	4,59	neutral	0,75	neutral	0,73	deleterious	4,3	24	0,25	0,55	disease	0,7	disease	0,89	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,58	medium_impact	-0,92	high_impact	3,14	0,28	0,9	2,14	6,81	P	0,56	P	0,84	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6706	6706	T	A	MI.3592	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	803	268	F	Y	tTt/tAt	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	2,74	neutral	-1,45	neutral	-2,15	high_impact	4,19	neutral	0,67	neutral	0,54	deleterious	4,33	24	0,23	0,55	disease	0,75	disease	0,84	disease	0,66	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-3,58	medium_impact	-0,92	high_impact	2,77	0,58	0,9	2,14	6,81	P	0,58	P	0,59	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6707	6707	T	A	MI.3593	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	804	268	F	L	ttT/ttA	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-2,1	deleterious	-4,18	high_impact	4,25	damaging	0,57	neutral	0,68	deleterious	4,48	24,3	0,38	0,55	neutral	0,34	disease	0,85	disease	0,73	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,83	0,51	0,9	2,14	6,81	P	0,55	P	0,83	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6707	6707	T	G	MI.3594	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	804	268	F	L	ttT/ttG	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-2,1	deleterious	-4,18	high_impact	4,25	damaging	0,57	neutral	0,68	deleterious	4,38	24,1	0,38	0,55	neutral	0,34	disease	0,85	disease	0,73	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,83	0,51	0,9	2,14	6,81	P	0,54	P	0,83	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6708	6708	G	T	MI.3595	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	805	269	G	W	Gga/Tga	-5,42	0	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-6,4	deleterious	-5,88	high_impact	4,95	damaging	0,52	damaging	0,15	deleterious	4,49	24,3	0,16	0,55	neutral	0,38	disease	0,92	disease	0,73	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,47	0,36	0,9	3,31	6,76	P	0,52	P	0,83	disease_causing	0,91	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6708	6708	G	C	MI.3596	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	805	269	G	R	Gga/Cga	-5,42	0	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-3,48	deleterious	-5,88	high_impact	5,3	damaging	0,51	damaging	0,12	deleterious	4	23,6	0,14	0,55	disease	0,79	disease	0,93	disease	0,77	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,58	0,9	3,31	6,76	P	0,64	P	0,95	disease_causing	0,87	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6709	6709	G	C	MI.3597	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	806	269	G	A	gGa/gCa	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,64	neutral	-2,76	deleterious	-4,4	high_impact	4,33	neutral	0,66	neutral	0,3	deleterious	3,14	22,6	0,17	0,55	disease	0,59	disease	0,83	disease	0,63	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,9	0,49	0,9	3,31	6,76	P	0,48	N	0,64	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6709	6709	G	A	MI.3598	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	806	269	G	E	gGa/gAa	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,63	neutral	-2,98	deleterious	-5,88	high_impact	5,3	damaging	0,46	damaging	0,16	deleterious	3,88	23,5	0,15	0,55	disease	0,72	disease	0,89	disease	0,73	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,49	0,9	3,31	6,76	P	0,72	P	0,93	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6709	6709	G	T	MI.3599	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	806	269	G	V	gGa/gTa	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-4,85	deleterious	-6,61	high_impact	5,3	damaging	0,49	damaging	0,16	deleterious	3,82	23,4	0,14	0,55	disease	0,74	disease	0,94	disease	0,68	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,39	0,9	3,31	6,76	P	0,62	P	0,93	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8542	8542	T	C	MI.36	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	16	6	F	L	Ttc/Ctc	0,13	0,97	0	probably_damaging	0,92	deleterious	0,01	neutral	4,01	neutral	-0,1	deleterious	-5,08	medium_impact	3,32	damaging	0,56	neutral	0,6	deleterious	3,9	23,5	0,46	0,65	disease	0,61	disease	0,63	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,73	low_impact	-1,76	medium_impact	-0,84	medium_impact	1,75	0,33	0,9	39,82	8,43	N	0,43	N	0,89	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8695	8695	A	C	MI.360	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	169	57	M	L	Atg/Ctg	3,83	1	0	possibly_damaging	0,81	neutral	0,96	neutral	4,62	neutral	2,65	neutral	-0,23	neutral_impact	-1,15	neutral	0,88	neutral	0,95	deleterious	0,33	6,02	0,53	0,65	neutral	0,45	neutral	0,18	neutral	0,25	neutral	0,28	4	neutral	0,8	deleterious	0,58	neutral	-3	deleterious	0,52	low_impact	-1,35	medium_impact	1,07	low_impact	-2,08	0,61	0,9	14,16	15,31	N	0,45	N	0,94	disease_causing	0,61	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6711	6711	T	C	MI.3600	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	808	270	Y	H	Tac/Cac	-12,13	0	0	probably_damaging	1	neutral	0,12	neutral	2,64	neutral	-1,7	neutral	-0,47	low_impact	1,41	neutral	0,66	neutral	0,45	deleterious	1,97	15,99	0,51	0,6	disease	0,69	disease	0,69	neutral	0,37	disease	0,54	1	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,8	low_impact	-3,58	medium_impact	-0,29	medium_impact	0,2	0,32	0,9	2,92	6,77	N	0,41	N	0,61	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6711	6711	T	G	MI.3601	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	808	270	Y	D	Tac/Gac	-12,13	0	0	probably_damaging	1	neutral	0,05	neutral	2,61	neutral	-2,33	neutral	-0,8	high_impact	3,76	neutral	0,65	neutral	0,4	deleterious	2,8	21,4	0,35	0,55	disease	0,58	disease	0,89	disease	0,64	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,82	low_impact	-3,58	medium_impact	-0,52	high_impact	2,37	0,4	0,9	2,92	6,77	N	0,42	N	0,98	polymorphism	0,96	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6711	6711	T	A	MI.3602	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	808	270	Y	N	Tac/Aac	-12,13	0	0	probably_damaging	1	neutral	0,16	neutral	2,64	neutral	-1,67	neutral	0,01	neutral_impact	0,72	neutral	0,63	neutral	0,68	deleterious	2,63	20,4	0,4	0,55	neutral	0,49	disease	0,74	neutral	0,39	disease	0,51	0	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,78	low_impact	-3,58	medium_impact	-0,21	medium_impact	-0,43	0,4	0,9	2,92	6,77	N	0,44	N	0,94	polymorphism	0,95	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6712	6712	A	T	MI.3603	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	809	270	Y	F	tAc/tTc	7,53	1	0	probably_damaging	1	neutral	0,2	neutral	2,6	neutral	-2,62	neutral	-0,61	low_impact	1,75	neutral	0,62	neutral	0,44	neutral	1,51	13,37	0,43	0,55	disease	0,69	disease	0,69	neutral	0,3	disease	0,53	1	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,81	low_impact	-3,58	medium_impact	-0,14	medium_impact	0,52	0,4	0,9	2,92	6,77	P	0,57	P	0,5	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6712	6712	A	G	MI.3604	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	809	270	Y	C	tAc/tGc	7,53	1	0	probably_damaging	1	neutral	0,07	neutral	2,56	deleterious	-5,33	neutral	-0,65	medium_impact	2,71	neutral	0,63	neutral	0,66	deleterious	2,24	17,76	0,32	0,55	disease	0,82	disease	0,87	neutral	0,41	disease	0,65	3	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,84	low_impact	-3,58	medium_impact	-0,43	medium_impact	1,4	0,17	0,9	2,92	6,77	P	0,5	N	0,89	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6712	6712	A	C	MI.3605	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	809	270	Y	S	tAc/tCc	7,53	1	0	probably_damaging	1	neutral	0,32	neutral	2,64	neutral	-1,68	neutral	0,74	neutral_impact	0,03	neutral	0,64	neutral	0,67	deleterious	2,02	16,34	0,31	0,55	neutral	0,28	disease	0,58	neutral	0,37	neutral	0,45	1	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,73	low_impact	-3,58	medium_impact	0,01	low_impact	-1,07	0,36	0,9	2,92	6,77	P	0,54	P	0,9	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6714	6714	A	G	MI.3606	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	811	271	M	V	Ata/Gta	-3,57	0	0	possibly_damaging	0,79	neutral	0,09	neutral	2,83	neutral	0,95	neutral	-0,8	neutral_impact	0,42	damaging	0,53	damaging	0,09	deleterious	0,78	9,31	0,65	0,7	neutral	0,31	disease	0,8	neutral	0,44	disease	0,52	0	neutral	0,94	neutral	0,15	neutral	-3	deleterious	0,6	low_impact	-1,3	medium_impact	-0,37	medium_impact	-0,71	0,63	0,9	2,14	6,71	N	0,3	N	0,88	disease_causing	0,51	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6714	6714	A	C	MI.3607	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	811	271	M	L	Ata/Cta	-3,57	0	0	possibly_damaging	0,7	neutral	1	neutral	2,84	neutral	1,22	neutral	1,11	neutral_impact	-2,77	damaging	0,57	damaging	0,24	neutral	-1,43	0	0,6	0,65	neutral	0,23	neutral	0,35	neutral	0,32	neutral	0,44	1	neutral	0,7	deleterious	0,65	neutral	-3	neutral	0,41	low_impact	-1,1	high_impact	1,86	low_impact	-3,66	0,61	0,9	2,14	6,71	N	0,25	N	0,61	polymorphism	0,54	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6714	6714	A	T	MI.3608	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	811	271	M	L	Ata/Tta	-3,57	0	0	possibly_damaging	0,7	neutral	1	neutral	2,84	neutral	1,22	neutral	1,11	neutral_impact	-2,77	damaging	0,57	damaging	0,24	neutral	-1,39	0	0,6	0,65	neutral	0,23	neutral	0,35	neutral	0,32	neutral	0,44	1	neutral	0,7	deleterious	0,65	neutral	-3	neutral	0,41	low_impact	-1,1	high_impact	1,86	low_impact	-3,66	0,61	0,9	2,14	6,71	N	0,25	N	0,61	polymorphism	0,54	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6715	6715	T	C	MI.3609	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	812	271	M	T	aTa/aCa	8,69	1	0	probably_damaging	0,95	neutral	0,13	neutral	2,9	neutral	2,14	neutral	-2,27	neutral_impact	0,01	damaging	0,55	damaging	0,19	neutral	1,04	10,88	0,55	0,6	neutral	0,19	disease	0,77	disease	0,63	disease	0,69	4	neutral	0,98	neutral	0,09	neutral	-2	deleterious	0,72	low_impact	-1,96	medium_impact	-0,27	low_impact	-1,09	0,48	0,9	2,14	6,71	N	0,44	N	0,79	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8696	8696	T	C	MI.361	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	170	57	M	T	aTg/aCg	-0,1	0,87	0	probably_damaging	0,94	neutral	0,11	neutral	4,45	neutral	1,25	deleterious	-3,61	low_impact	1,18	neutral	0,93	neutral	0,67	deleterious	2,83	21,5	0,34	0,65	disease	0,65	disease	0,57	disease	0,56	disease	0,62	2	neutral	0,98	neutral	0,09	neutral	-2	deleterious	0,78	low_impact	-1,89	medium_impact	-0,22	medium_impact	-0,09	0,34	0,9	14,16	15,31	N	0,37	N	0,97	polymorphism	0,78	0,06	.	.	.	.	.	pancreatic cancer cell line	.	.	.	.	.	.	.	.	.
chrM	6715	6715	T	A	MI.3610	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	812	271	M	K	aTa/aAa	8,69	1	0	possibly_damaging	0,9	deleterious	0	neutral	3,13	neutral	3,82	deleterious	-2,97	neutral_impact	0,28	neutral	0,62	damaging	0,1	deleterious	2,12	16,98	0,33	0,55	neutral	0,16	disease	0,88	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,7	low_impact	-1,65	low_impact	-1,48	medium_impact	-0,84	0,63	0,9	2,14	6,71	N	0,41	N	0,93	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6716	6716	A	C	MI.3611	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	813	271	M	I	atA/atC	5,91	1	0	possibly_damaging	0,85	neutral	0,05	neutral	2,82	neutral	0,47	neutral	-0,14	neutral_impact	-1,04	damaging	0,55	damaging	0,12	neutral	1,55	13,57	0,63	0,65	neutral	0,34	disease	0,69	neutral	0,38	neutral	0,48	0	neutral	0,97	neutral	0,1	neutral	-3	deleterious	0,64	low_impact	-1,47	medium_impact	-0,52	low_impact	-2,06	0,67	0,9	2,14	6,71	P	0,56	P	0,87	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6716	6716	A	T	MI.3612	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	813	271	M	I	atA/atT	5,91	1	0	possibly_damaging	0,85	neutral	0,05	neutral	2,82	neutral	0,47	neutral	-0,14	neutral_impact	-1,04	damaging	0,55	damaging	0,12	neutral	1,68	14,27	0,63	0,65	neutral	0,34	disease	0,69	neutral	0,38	neutral	0,48	0	neutral	0,97	neutral	0,1	neutral	-3	deleterious	0,64	low_impact	-1,47	medium_impact	-0,52	low_impact	-2,06	0,67	0,9	2,14	6,71	P	0,57	P	0,87	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6717	6717	G	C	MI.3613	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	814	272	G	R	Ggt/Cgt	-0,1	0,69	0	probably_damaging	1	deleterious	0	neutral	2,73	neutral	-2,11	deleterious	-5,54	high_impact	4,83	neutral	0,6	damaging	0,19	deleterious	3,91	23,5	0,14	0,55	neutral	0,43	disease	0,94	disease	0,79	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,36	0,8	0,9	2,14	6,69	P	0,65	P	0,95	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6717	6717	G	T	MI.3614	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	814	272	G	C	Ggt/Tgt	-0,1	0,69	0	probably_damaging	1	deleterious	0	neutral	2,73	neutral	-2,53	deleterious	-6,23	high_impact	4,62	damaging	0,55	damaging	0,2	deleterious	4,12	23,8	0,19	0,55	disease	0,71	disease	0,94	disease	0,7	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,17	0,75	0,9	2,14	6,69	N	0,42	N	0,98	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6717	6717	G	A	MI.3615	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	814	272	G	S	Ggt/Agt	-0,1	0,69	0	probably_damaging	1	neutral	0,14	neutral	2,81	neutral	0,07	deleterious	-3,94	medium_impact	2,6	damaging	0,46	neutral	0,61	deleterious	3,06	22,4	0,35	0,55	neutral	0,2	disease	0,86	neutral	0,48	neutral	0,16	7	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,77	low_impact	-3,58	medium_impact	-0,25	medium_impact	1,3	0,76	0,9	2,14	6,69	N	0,45	N	0,73	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6718	6718	G	C	MI.3616	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	815	272	G	A	gGt/gCt	9,15	1	0	probably_damaging	1	neutral	0,08	neutral	2,84	neutral	0,38	deleterious	-4,07	medium_impact	2,98	neutral	0,72	neutral	0,38	deleterious	3,13	22,6	0,35	0,55	neutral	0,21	disease	0,83	neutral	0,48	neutral	0,18	6	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,76	low_impact	-3,58	medium_impact	-0,4	medium_impact	1,65	0,69	0,9	2,14	6,69	P	0,53	P	0,64	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6718	6718	G	A	MI.3617	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	815	272	G	D	gGt/gAt	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,72	deleterious	-3,23	deleterious	-4,81	high_impact	5,17	damaging	0,57	damaging	0,22	deleterious	3,85	23,4	0,16	0,55	neutral	0,32	disease	0,93	disease	0,78	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,49	0,9	2,14	6,69	P	0,73	P	0,97	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6718	6718	G	T	MI.3618	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	815	272	G	V	gGt/gTt	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,92	neutral	1,17	deleterious	-6,27	high_impact	4,62	damaging	0,57	damaging	0,26	deleterious	3,77	23,4	0,16	0,55	neutral	0,27	disease	0,94	disease	0,69	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,17	0,62	0,9	2,14	6,69	P	0,5	N	0,93	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6720	6720	A	T	MI.3619	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	817	273	M	L	Atg/Ttg	-6,12	0	0	probably_damaging	0,91	neutral	0,06	neutral	2,83	neutral	-0,9	neutral	-2,19	medium_impact	3,12	damaging	0,59	damaging	0,07	deleterious	3,46	23	0,49	0,55	neutral	0,33	disease	0,85	disease	0,71	disease	0,72	4	neutral	0,98	neutral	0,08	deleterious	1	deleterious	0,61	low_impact	-1,7	medium_impact	-0,47	medium_impact	1,78	0,52	0,9	3,7	8,28	N	0,26	N	0,61	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8696	8696	T	A	MI.362	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	170	57	M	K	aTg/aAg	-0,1	0,87	0	probably_damaging	0,94	neutral	0,2	neutral	4,37	neutral	-0,91	deleterious	-4,34	medium_impact	2,52	neutral	0,84	neutral	0,36	deleterious	4,04	23,7	0,15	0,65	disease	0,72	disease	0,75	disease	0,68	disease	0,71	4	neutral	0,96	neutral	0,13	deleterious	1	deleterious	0,82	low_impact	-1,89	medium_impact	-0,05	medium_impact	1,06	0,56	0,9	14,16	15,31	N	0,28	N	0,99	disease_causing	0,68	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6720	6720	A	G	MI.3620	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	817	273	M	V	Atg/Gtg	-6,12	0	0	probably_damaging	0,94	deleterious	0	neutral	2,73	neutral	-0,91	deleterious	-2,92	high_impact	3,79	damaging	0,5	damaging	0,12	deleterious	2,81	21,4	0,45	0,55	neutral	0,36	disease	0,9	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,73	low_impact	-1,88	low_impact	-1,48	high_impact	2,4	0,46	0,9	3,7	8,28	N	0,33	N	0,88	polymorphism	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6720	6720	A	C	MI.3621	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	817	273	M	L	Atg/Ctg	-6,12	0	0	probably_damaging	0,91	neutral	0,06	neutral	2,83	neutral	-0,9	neutral	-2,19	medium_impact	3,12	damaging	0,59	damaging	0,07	deleterious	3,42	23	0,49	0,55	neutral	0,33	disease	0,85	disease	0,71	disease	0,72	4	neutral	0,98	neutral	0,08	deleterious	1	deleterious	0,61	low_impact	-1,7	medium_impact	-0,47	medium_impact	1,78	0,52	0,9	3,7	8,28	N	0,26	N	0,61	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6721	6721	T	C	MI.3622	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	818	273	M	T	aTg/aCg	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,64	neutral	-2,34	deleterious	-4,37	high_impact	5,24	neutral	0,61	damaging	0,1	deleterious	3,03	22,3	0,36	0,55	neutral	0,46	disease	0,91	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,64	low_impact	-1,48	high_impact	3,74	0,4	0,9	3,7	8,28	P	0,72	P	0,79	disease_causing_automatic	1	0,22	rs199476127	Pathogenic	Sideroblastic_anemia,_acquired_idiopathic	RCV000010303.2	MedGen	bone marrow, whole blood, platelets, granulocytes	.	.	.	T6721C	Acquired Idiopathic Sideroblastic Anemia	-	+	Reported	2
chrM	6721	6721	T	A	MI.3623	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	818	273	M	K	aTg/aAg	8,69	1	0	probably_damaging	0,97	deleterious	0	neutral	2,59	deleterious	-3,52	deleterious	-4,37	high_impact	4,88	damaging	0,54	damaging	0,08	deleterious	3,93	23,5	0,2	0,55	disease	0,66	disease	0,93	disease	0,77	disease	0,8	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,85	low_impact	-2,18	low_impact	-1,48	high_impact	3,41	0,37	0,9	3,7	8,28	P	0,71	P	0,93	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6722	6722	G	T	MI.3624	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	819	273	M	I	atG/atT	4,76	1	0	probably_damaging	0,96	deleterious	0	neutral	2,69	neutral	-1,3	deleterious	-2,92	high_impact	3,88	damaging	0,52	damaging	0,1	deleterious	3,72	23,3	0,4	0,55	neutral	0,29	disease	0,91	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,76	low_impact	-2,06	low_impact	-1,48	high_impact	2,48	0,61	0,9	3,7	8,28	N	0,43	N	0,87	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6722	6722	G	C	MI.3625	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	819	273	M	I	atG/atC	4,76	1	0	probably_damaging	0,96	deleterious	0	neutral	2,69	neutral	-1,3	deleterious	-2,92	high_impact	3,88	damaging	0,52	damaging	0,1	deleterious	3,61	23,2	0,4	0,55	neutral	0,29	disease	0,91	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,76	low_impact	-2,06	low_impact	-1,48	high_impact	2,48	0,61	0,9	3,7	8,28	N	0,42	N	0,87	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6723	6723	G	C	MI.3626	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	820	274	V	L	Gtc/Ctc	0,36	0,97	0	benign	0,09	deleterious	0,01	neutral	2,69	neutral	-1,48	neutral	-1,02	medium_impact	2,52	neutral	0,6	neutral	0,51	neutral	1,71	14,49	0,33	0,55	neutral	0,35	disease	0,78	neutral	0,49	disease	0,6	2	deleterious	0,99	neutral	0,46	deleterious	1	neutral	0,31	medium_impact	0,19	medium_impact	-0,92	medium_impact	1,23	0,73	0,9	3,9	9,77	N	0,45	N	0,55	disease_causing	0,98	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6723	6723	G	T	MI.3627	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	820	274	V	F	Gtc/Ttc	0,36	0,97	0	possibly_damaging	0,89	deleterious	0	neutral	2,58	neutral	-2,96	neutral	-2,46	medium_impact	3,02	damaging	0,58	neutral	0,48	deleterious	3,75	23,3	0,16	0,55	disease	0,63	disease	0,9	neutral	0,46	disease	0,73	5	deleterious	1	neutral	0,06	deleterious	4	deleterious	0,79	low_impact	-1,61	low_impact	-1,48	medium_impact	1,69	0,64	0,9	3,9	9,77	N	0,43	N	0,86	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6723	6723	G	A	MI.3628	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	820	274	V	I	Gtc/Atc	0,36	0,97	0	benign	0,09	neutral	0,66	neutral	2,68	neutral	-1,03	neutral	0,41	neutral_impact	-1,21	neutral	0,65	neutral	0,71	neutral	-0,94	0,02	0,39	0,55	neutral	0,24	neutral	0,16	neutral	0,17	neutral	0,27	5	neutral	0,24	deleterious	0,79	neutral	-6	neutral	0,16	medium_impact	0,19	medium_impact	0,35	low_impact	-2,22	0,78	0,9	3,9	9,77	N	0,41	N	0,24	disease_causing	0,94	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6724	6724	T	A	MI.3629	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	821	274	V	D	gTc/gAc	6,14	1	0	probably_damaging	0,91	deleterious	0	neutral	2,53	deleterious	-5,15	deleterious	-4,46	high_impact	3,72	damaging	0,6	neutral	0,48	deleterious	4,49	24,3	0,07	0,55	disease	0,86	disease	0,91	disease	0,64	disease	0,8	6	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,85	low_impact	-1,7	low_impact	-1,48	high_impact	2,34	0,59	0,9	3,9	9,77	N	0,41	N	0,83	disease_causing	1	0,37	rs28393263	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8697	8697	G	C	MI.363	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	171	57	M	I	atG/atC	7,53	0,99	0,1	probably_damaging	0,91	neutral	0,41	neutral	4,63	neutral	2,75	neutral	-1,08	neutral_impact	-0,34	neutral	0,84	neutral	0,73	deleterious	1,96	15,94	0,59	0,7	neutral	0,38	neutral	0,34	neutral	0,29	neutral	0,47	1	neutral	0,91	neutral	0,25	neutral	-2	deleterious	0,64	low_impact	-1,71	medium_impact	0,2	low_impact	-1,39	0,68	0,9	14,16	15,31	N	0,47	N	0,92	disease_causing	0,67	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6724	6724	T	C	MI.3630	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	821	274	V	A	gTc/gCc	6,14	1	0	benign	0,41	deleterious	0,02	neutral	2,64	neutral	-1,57	deleterious	-2,86	medium_impact	2,15	neutral	0,62	neutral	0,62	deleterious	3,1	22,5	0,26	0,55	neutral	0,29	disease	0,66	neutral	0,34	neutral	0,46	1	neutral	0,98	neutral	0,31	deleterious	1	neutral	0,39	medium_impact	-0,61	medium_impact	-0,75	medium_impact	0,89	0,55	0,9	3,9	9,77	P	0,51	P	0,47	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6724	6724	T	G	MI.3631	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	821	274	V	G	gTc/gGc	6,14	1	0	possibly_damaging	0,9	deleterious	0,02	neutral	2,54	deleterious	-4,36	deleterious	-5,04	medium_impact	3,17	damaging	0,6	neutral	0,59	deleterious	3,81	23,4	0,14	0,55	disease	0,77	disease	0,82	disease	0,53	disease	0,73	5	deleterious	0,99	neutral	0,06	deleterious	4	deleterious	0,78	low_impact	-1,65	medium_impact	-0,75	medium_impact	1,83	0,55	0,9	3,9	9,77	N	0,48	N	0,71	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6726	6726	T	C	MI.3632	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	823	275	W	R	Tga/Cga	-12,6	0	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-1,67	deleterious	-3,64	low_impact	1,84	damaging	0,5	damaging	0,05	deleterious	3,59	23,2	0,34	0,55	neutral	0,49	disease	0,92	disease	0,67	disease	0,81	6	deleterious	1	neutral	0	deleterious	2	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	medium_impact	0,6	0,49	0,9	5,07	8,67	N	0,25	N	0,98	polymorphism	0,98	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6726	6726	T	G	MI.3633	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	823	275	W	G	Tga/Gga	-12,6	0	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-1,71	deleterious	-4,22	neutral_impact	0,32	damaging	0,54	damaging	0,07	deleterious	3,87	23,5	0,31	0,55	neutral	0,27	disease	0,77	disease	0,63	disease	0,74	5	deleterious	1	neutral	0	deleterious	2	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	medium_impact	-0,8	0,44	0,9	5,07	8,67	N	0,26	N	0,89	polymorphism	0,95	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6727	6727	G	C	MI.3634	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	824	275	W	S	tGa/tCa	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,82	neutral	0,29	deleterious	-3,63	low_impact	0,87	damaging	0,48	damaging	0,05	deleterious	4,04	23,7	0,3	0,55	neutral	0,31	disease	0,8	disease	0,61	disease	0,74	5	deleterious	1	neutral	0	deleterious	2	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	medium_impact	-0,3	0,43	0,9	5,07	8,67	N	0,4	N	0,89	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6727	6727	G	T	MI.3635	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	824	275	W	L	tGa/tTa	5,91	1	0	probably_damaging	1	deleterious	0	neutral	3,04	neutral	2,25	deleterious	-2,91	neutral_impact	0,2	damaging	0,54	damaging	0,04	deleterious	4,3	24	0,29	0,55	neutral	0,16	disease	0,77	disease	0,59	disease	0,73	5	deleterious	1	neutral	0	deleterious	2	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	medium_impact	-0,91	0,37	0,9	5,07	8,67	N	0,37	N	0,95	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6728	6728	A	T	MI.3636	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	825	275	W	C	tgA/tgT	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-0,74	deleterious	-3,57	neutral_impact	0,6	damaging	0,52	damaging	0,05	deleterious	4,16	23,8	0,36	0,55	neutral	0,45	disease	0,87	disease	0,58	disease	0,73	5	deleterious	1	neutral	0	deleterious	2	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	medium_impact	-0,55	0,57	0,9	5,07	8,67	N	0,37	N	0,88	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6728	6728	A	C	MI.3637	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	825	275	W	C	tgA/tgC	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-0,74	deleterious	-3,57	neutral_impact	0,6	damaging	0,52	damaging	0,05	deleterious	4,06	23,7	0,36	0,55	neutral	0,45	disease	0,87	disease	0,58	disease	0,73	5	deleterious	1	neutral	0	deleterious	2	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	medium_impact	-0,55	0,57	0,9	5,07	8,67	N	0,37	N	0,88	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6729	6729	G	T	MI.3638	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	826	276	A	S	Gct/Tct	-0,1	0,84	0	probably_damaging	0,99	deleterious	0	neutral	2,69	neutral	-1,63	neutral	-2,18	medium_impact	3,49	neutral	0,68	damaging	0,15	deleterious	3,73	23,3	0,2	0,55	neutral	0,28	disease	0,76	disease	0,56	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	high_impact	2,12	0,84	0,9	4,09	8,37	N	0,3	N	0,64	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6729	6729	G	A	MI.3639	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	826	276	A	T	Gct/Act	-0,1	0,84	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-3,11	deleterious	-2,91	high_impact	5,28	damaging	0,46	damaging	0,18	deleterious	4,22	23,9	0,27	0,55	disease	0,61	disease	0,81	disease	0,59	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,73	0,9	4,09	8,37	P	0,65	P	0,2	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8697	8697	G	T	MI.364	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	171	57	M	I	atG/atT	7,53	0,99	0,1	probably_damaging	0,91	neutral	0,41	neutral	4,63	neutral	2,75	neutral	-1,08	neutral_impact	-0,34	neutral	0,84	neutral	0,73	deleterious	2,11	16,91	0,59	0,7	neutral	0,38	neutral	0,34	neutral	0,29	neutral	0,47	1	neutral	0,91	neutral	0,25	neutral	-2	deleterious	0,64	low_impact	-1,71	medium_impact	0,2	low_impact	-1,39	0,68	0,9	14,16	15,31	N	0,47	N	0,92	disease_causing	0,67	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6729	6729	G	C	MI.3640	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	826	276	A	P	Gct/Cct	-0,1	0,84	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-4,32	deleterious	-3,65	high_impact	5,28	damaging	0,52	damaging	0,15	deleterious	3,87	23,5	0,11	0,55	disease	0,81	disease	0,83	disease	0,76	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,74	0,9	4,09	8,37	P	0,66	P	0,85	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6730	6730	C	A	MI.3641	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	827	276	A	D	gCt/gAt	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-3,49	deleterious	-4,38	high_impact	5,28	damaging	0,59	damaging	0,12	deleterious	4,59	24,4	0,08	0,55	disease	0,76	disease	0,88	disease	0,75	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,7	0,9	4,09	8,37	P	0,75	P	0,89	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6730	6730	C	G	MI.3642	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	827	276	A	G	gCt/gGt	5,22	1	0	probably_damaging	0,98	deleterious	0	neutral	2,61	neutral	-2,47	deleterious	-2,92	high_impact	4,48	damaging	0,59	damaging	0,15	deleterious	3,95	23,6	0,15	0,55	disease	0,7	disease	0,71	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,35	low_impact	-1,48	high_impact	3,04	0,8	0,9	4,09	8,37	P	0,51	P	0,56	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6730	6730	C	T	MI.3643	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	827	276	A	V	gCt/gTt	5,22	1	0	probably_damaging	0,99	deleterious	0	neutral	2,59	neutral	-2,79	deleterious	-2,92	high_impact	4,93	damaging	0,53	damaging	0,12	deleterious	4,4	24,1	0,28	0,55	disease	0,74	disease	0,86	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	3,45	0,71	0,9	4,09	8,37	P	0,75	P	0,75	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6732	6732	A	C	MI.3644	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	829	277	M	L	Atg/Ctg	-10,51	0	0	probably_damaging	0,91	deleterious	0,01	neutral	2,79	neutral	-0,16	neutral	-2,08	high_impact	3,56	neutral	0,62	damaging	0,05	deleterious	3,42	23	0,44	0,55	neutral	0,24	disease	0,89	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,69	low_impact	-1,7	medium_impact	-0,92	high_impact	2,19	0,63	0,9	2,53	6,72	N	0,27	N	0,61	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6732	6732	A	G	MI.3645	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	829	277	M	V	Atg/Gtg	-10,51	0	0	probably_damaging	0,94	deleterious	0	neutral	2,78	neutral	-0,21	deleterious	-2,77	high_impact	4,11	damaging	0,56	damaging	0,08	deleterious	2,82	21,5	0,48	0,55	neutral	0,29	disease	0,93	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,77	low_impact	-1,88	low_impact	-1,48	high_impact	2,7	0,64	0,9	2,53	6,72	N	0,29	N	0,88	polymorphism	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6732	6732	A	T	MI.3646	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	829	277	M	L	Atg/Ttg	-10,51	0	0	probably_damaging	0,91	deleterious	0,01	neutral	2,79	neutral	-0,16	neutral	-2,08	high_impact	3,56	neutral	0,62	damaging	0,05	deleterious	3,48	23,1	0,44	0,55	neutral	0,24	disease	0,89	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,69	low_impact	-1,7	medium_impact	-0,92	high_impact	2,19	0,63	0,9	2,53	6,72	N	0,27	N	0,61	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6733	6733	T	C	MI.3647	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	830	277	M	T	aTg/aCg	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,77	neutral	-0,32	deleterious	-4,24	medium_impact	3,04	damaging	0,58	damaging	0,09	deleterious	3	22,2	0,36	0,55	neutral	0,3	disease	0,92	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-2,64	low_impact	-1,48	medium_impact	1,71	0,41	0,9	2,53	6,72	N	0,39	N	0,79	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6733	6733	T	A	MI.3648	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	830	277	M	K	aTg/aAg	8,69	1	0	probably_damaging	0,97	deleterious	0	neutral	2,65	deleterious	-3,04	deleterious	-4,29	high_impact	5,14	damaging	0,55	damaging	0,06	deleterious	3,93	23,5	0,23	0,55	disease	0,55	disease	0,95	disease	0,74	disease	0,85	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-2,18	low_impact	-1,48	high_impact	3,65	0,51	0,9	2,53	6,72	P	0,69	P	0,93	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6734	6734	G	C	MI.3649	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	831	277	M	I	atG/atC	7,53	1	0,02	probably_damaging	0,96	neutral	0,11	neutral	2,84	neutral	0,27	deleterious	-2,75	medium_impact	2,5	damaging	0,51	damaging	0,13	deleterious	3,57	23,1	0,43	0,55	neutral	0,24	disease	0,92	neutral	0,5	neutral	0,47	1	deleterious	0,98	neutral	0,08	deleterious	1	deleterious	0,79	low_impact	-2,06	medium_impact	-0,31	medium_impact	1,21	0,73	0,9	2,53	6,72	N	0,45	N	0,87	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8698	8698	A	T	MI.365	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	172	58	M	L	Ata/Tta	-1,03	0	0	possibly_damaging	0,81	neutral	0,67	neutral	4,38	neutral	-0,22	neutral	-1,32	neutral_impact	0,19	neutral	0,9	neutral	0,98	neutral	1,03	10,84	0,69	0,75	NA	NA	neutral	0,3	neutral	0,25	neutral	0,2	6	neutral	0,77	neutral	0,43	neutral	-3	deleterious	0,56	low_impact	-1,35	medium_impact	0,47	medium_impact	-0,94	0,58	0,9	40,71	8,78	N	0,33	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6734	6734	G	T	MI.3650	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	831	277	M	I	atG/atT	7,53	1	0,02	probably_damaging	0,96	neutral	0,11	neutral	2,84	neutral	0,27	deleterious	-2,75	medium_impact	2,5	damaging	0,51	damaging	0,13	deleterious	3,69	23,3	0,43	0,55	neutral	0,24	disease	0,92	neutral	0,5	neutral	0,47	1	deleterious	0,98	neutral	0,08	deleterious	1	deleterious	0,79	low_impact	-2,06	medium_impact	-0,31	medium_impact	1,21	0,73	0,9	2,53	6,72	N	0,46	N	0,87	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6735	6735	A	G	MI.3651	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	832	278	M	V	Ata/Gta	-1,03	0	0	benign	0	neutral	0,21	neutral	2,97	neutral	1,83	neutral	-0,3	neutral_impact	0,26	neutral	0,79	neutral	0,95	neutral	-0,51	0,21	0,52	0,6	neutral	0,19	disease	0,75	neutral	0,27	neutral	0,41	2	neutral	0,79	deleterious	0,61	neutral	-6	neutral	0,19	high_impact	2,07	medium_impact	-0,13	medium_impact	-0,86	0,62	0,9	9,36	31,7	N	0,36	N	0,01	polymorphism	0,65	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6735	6735	A	T	MI.3652	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	832	278	M	L	Ata/Tta	-1,03	0	0	benign	0	neutral	0,78	neutral	2,98	neutral	1,88	neutral	-0,01	neutral_impact	-0,58	neutral	0,63	neutral	0,72	neutral	-1,2	0,01	0,47	0,55	neutral	0,18	disease	0,62	neutral	0,25	neutral	0,39	2	neutral	0,21	deleterious	0,89	neutral	-6	neutral	0,18	high_impact	2,07	medium_impact	0,5	low_impact	-1,64	0,62	0,9	9,36	31,7	N	0,38	N	0,4	polymorphism	0,7	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6735	6735	A	C	MI.3653	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	832	278	M	L	Ata/Cta	-1,03	0	0	benign	0	neutral	0,78	neutral	2,98	neutral	1,88	neutral	-0,01	neutral_impact	-0,58	neutral	0,63	neutral	0,72	neutral	-1,27	0,01	0,47	0,55	neutral	0,18	disease	0,62	neutral	0,25	neutral	0,39	2	neutral	0,21	deleterious	0,89	neutral	-6	neutral	0,18	high_impact	2,07	medium_impact	0,5	low_impact	-1,64	0,62	0,9	9,36	31,7	N	0,37	N	0,4	polymorphism	0,7	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6736	6736	T	C	MI.3654	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	833	278	M	T	aTa/aCa	3,14	0,99	0	benign	0,05	deleterious	0,02	neutral	2,81	neutral	0,14	neutral	-1,88	low_impact	1,23	neutral	0,64	neutral	0,53	deleterious	0,03	2,84	0,33	0,55	neutral	0,32	disease	0,82	neutral	0,35	neutral	0,45	1	neutral	0,98	deleterious	0,49	neutral	-2	neutral	0,27	medium_impact	0,45	medium_impact	-0,75	medium_impact	0,04	0,5	0,9	9,36	31,7	N	0,47	N	0,68	disease_causing	0,92	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6736	6736	T	A	MI.3655	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	833	278	M	K	aTa/aAa	3,14	0,99	0	benign	0,05	deleterious	0	neutral	2,76	neutral	-1,58	deleterious	-2,68	medium_impact	3,12	neutral	0,64	neutral	0,38	deleterious	2,13	17,06	0,15	0,55	disease	0,51	disease	0,94	disease	0,6	disease	0,82	6	deleterious	1	deleterious	0,48	deleterious	1	neutral	0,33	medium_impact	0,45	low_impact	-1,48	medium_impact	1,78	0,6	0,9	9,36	31,7	N	0,45	N	0,83	disease_causing	0,99	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6737	6737	A	C	MI.3656	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	834	278	M	I	atA/atC	7,53	1	0,01	benign	0	neutral	0,39	neutral	2,97	neutral	1,78	neutral	-0,16	neutral_impact	-0,16	neutral	0,74	neutral	0,78	deleterious	0,07	3,24	0,47	0,55	neutral	0,17	disease	0,79	neutral	0,25	neutral	0,42	2	neutral	0,61	deleterious	0,7	neutral	-6	neutral	0,21	high_impact	2,07	medium_impact	0,09	low_impact	-1,25	0,68	0,9	9,36	31,7	P	0,51	P	0,5	disease_causing	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6737	6737	A	T	MI.3657	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	834	278	M	I	atA/atT	7,53	1	0,01	benign	0	neutral	0,39	neutral	2,97	neutral	1,78	neutral	-0,16	neutral_impact	-0,16	neutral	0,74	neutral	0,78	deleterious	0,13	3,93	0,47	0,55	neutral	0,17	disease	0,79	neutral	0,25	neutral	0,42	2	neutral	0,61	deleterious	0,7	neutral	-6	neutral	0,21	high_impact	2,07	medium_impact	0,09	low_impact	-1,25	0,68	0,9	9,36	31,7	P	0,51	P	0,5	disease_causing	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6738	6738	T	C	MI.3658	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	835	279	S	P	Tca/Cca	-0,33	0,18	0	probably_damaging	1	deleterious	0,01	neutral	2,65	deleterious	-3,52	neutral	-1,84	high_impact	3,76	damaging	0,41	damaging	0,06	deleterious	4	23,6	0,13	0,55	disease	0,6	disease	0,96	disease	0,65	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,58	medium_impact	-0,92	high_impact	2,37	0,71	0,9	1,56	6,63	N	0,46	N	0,91	disease_causing	0,78	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6738	6738	T	G	MI.3659	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	835	279	S	A	Tca/Gca	-0,33	0,18	0	probably_damaging	0,99	neutral	0,88	neutral	2,89	neutral	0,58	neutral	0,58	neutral_impact	-0,06	neutral	0,61	neutral	0,41	neutral	0,99	10,63	0,38	0,55	neutral	0,19	neutral	0,38	neutral	0,26	neutral	0,44	1	deleterious	0,99	neutral	0,45	neutral	-2	deleterious	0,64	low_impact	-2,64	medium_impact	0,67	low_impact	-1,15	0,78	0,9	1,56	6,63	N	0,27	N	0,35	polymorphism	0,85	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8698	8698	A	C	MI.366	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	172	58	M	L	Ata/Cta	-1,03	0	0	possibly_damaging	0,81	neutral	0,67	neutral	4,38	neutral	-0,22	neutral	-1,32	neutral_impact	0,19	neutral	0,9	neutral	0,98	neutral	0,96	10,44	0,69	0,75	NA	NA	neutral	0,3	neutral	0,25	neutral	0,2	6	neutral	0,77	neutral	0,43	neutral	-3	deleterious	0,56	low_impact	-1,35	medium_impact	0,47	medium_impact	-0,94	0,58	0,9	40,71	8,78	N	0,33	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6738	6738	T	A	MI.3660	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	835	279	S	T	Tca/Aca	-0,33	0,18	0	probably_damaging	0,98	neutral	0,15	neutral	2,76	neutral	-0,44	neutral	-0,6	low_impact	1,07	damaging	0,52	damaging	0,12	deleterious	2,58	19,96	0,25	0,55	neutral	0,37	disease	0,77	neutral	0,31	neutral	0,43	1	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,75	low_impact	-2,35	medium_impact	-0,23	medium_impact	-0,11	0,87	0,9	1,56	6,63	N	0,35	N	0,43	polymorphism	0,64	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6739	6739	C	G	MI.3661	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	836	279	S	W	tCa/tGa	5,91	1	0	probably_damaging	1	neutral	0,08	neutral	2,65	deleterious	-3,74	deleterious	-2,92	high_impact	3,96	damaging	0,44	damaging	0,05	deleterious	4,3	24	0,13	0,55	disease	0,8	disease	0,97	disease	0,58	disease	0,78	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,86	low_impact	-3,58	medium_impact	-0,4	high_impact	2,56	0,49	0,9	1,56	6,63	P	0,53	P	0,94	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6739	6739	C	T	MI.3662	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	836	279	S	L	tCa/tTa	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,9	neutral	0,67	neutral	-2,25	medium_impact	3,27	damaging	0,46	damaging	0,05	deleterious	4,62	24,5	0,17	0,55	neutral	0,28	disease	0,95	neutral	0,49	disease	0,76	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	medium_impact	1,92	0,9	0,95	1,56	6,63	P	0,5	N	0,9	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6741	6741	A	C	MI.3663	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	838	280	I	L	Att/Ctt	-13,75	0	0	probably_damaging	0,98	deleterious	0	neutral	2,66	neutral	-1,57	neutral	-1,45	high_impact	4,61	neutral	0,65	damaging	0,09	deleterious	3,83	23,4	0,3	0,55	neutral	0,5	disease	0,62	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,67	low_impact	-2,35	low_impact	-1,48	high_impact	3,16	0,67	0,9	3,7	8,34	N	0,4	N	0,61	polymorphism	0,97	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6741	6741	A	T	MI.3664	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	838	280	I	F	Att/Ttt	-13,75	0	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-3,91	deleterious	-2,9	high_impact	5,29	damaging	0,6	damaging	0,07	deleterious	4,03	23,6	0,23	0,55	disease	0,7	disease	0,78	disease	0,64	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,7	0,9	3,7	8,34	P	0,61	P	0,85	disease_causing	0,76	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6741	6741	A	G	MI.3665	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	838	280	I	V	Att/Gtt	-13,75	0	0	probably_damaging	0,95	deleterious	0,01	neutral	2,5	neutral	-2,18	neutral	-0,72	high_impact	4,61	neutral	0,63	damaging	0,12	deleterious	3,05	22,4	0,4	0,55	neutral	0,5	disease	0,53	disease	0,57	disease	0,63	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,64	low_impact	-1,96	medium_impact	-0,92	high_impact	3,16	0,54	0,9	3,7	8,34	N	0,43	N	0,23	polymorphism	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6742	6742	T	C	MI.3666	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	839	280	I	T	aTt/aCt	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-3,79	deleterious	-3,62	high_impact	4,75	neutral	0,6	damaging	0,09	deleterious	3,45	23	0,33	0,55	disease	0,52	disease	0,7	disease	0,63	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,49	0,9	3,7	8,34	P	0,63	P	0,76	disease_causing_automatic	1	0,26	rs199476126	Pathogenic	Sideroblastic_anemia,_acquired_idiopathic	RCV000010302.2	MedGen	bone marrow, whole blood, platelets,  granulocytes	.	.	.	T6742C	Acquired Idiopathic Sideroblastic Anemia	-	+	Reported	2
chrM	6742	6742	T	A	MI.3667	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	839	280	I	N	aTt/aAt	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,39	deleterious	-5,66	deleterious	-5,08	high_impact	4,95	damaging	0,57	damaging	0,09	deleterious	4,49	24,3	0,19	0,55	disease	0,75	disease	0,78	disease	0,66	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,47	0,46	0,9	3,7	8,34	P	0,66	P	0,94	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6742	6742	T	G	MI.3668	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	839	280	I	S	aTt/aGt	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-4,54	deleterious	-4,35	high_impact	5,29	neutral	0,61	damaging	0,14	deleterious	4,31	24	0,21	0,55	disease	0,64	disease	0,79	disease	0,63	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,37	0,9	3,7	8,34	P	0,7	P	0,62	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6743	6743	T	A	MI.3669	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	840	280	I	M	atT/atA	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,43	deleterious	-4,39	neutral	-2,18	high_impact	4,5	neutral	0,63	damaging	0,09	deleterious	3,71	23,3	0,28	0,55	disease	0,56	disease	0,63	disease	0,64	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,73	0,9	3,7	8,34	P	0,49	N	0,76	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8698	8698	A	G	MI.367	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	172	58	M	V	Ata/Gta	-1,03	0	0	possibly_damaging	0,87	neutral	0,5	neutral	4,44	neutral	0,94	deleterious	-2,58	low_impact	1,57	neutral	0,81	neutral	0,51	deleterious	2,56	19,85	0,74	0,8	NA	NA	disease	0,58	neutral	0,47	neutral	0,47	1	neutral	0,86	neutral	0,32	neutral	-3	deleterious	0,66	low_impact	-1,54	medium_impact	0,29	medium_impact	0,25	0,48	0,9	40,71	8,78	N	0,23	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6743	6743	T	G	MI.3670	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	840	280	I	M	atT/atG	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,43	deleterious	-4,39	neutral	-2,18	high_impact	4,5	neutral	0,63	damaging	0,09	deleterious	3,45	23	0,28	0,55	disease	0,56	disease	0,63	disease	0,64	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,73	0,9	3,7	8,34	P	0,48	N	0,76	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6744	6744	G	T	MI.3671	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	841	281	G	C	Ggc/Tgc	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-2,41	deleterious	-6,24	high_impact	4,32	damaging	0,37	damaging	0,01	deleterious	4,12	23,8	0,18	0,55	disease	0,72	disease	0,94	disease	0,61	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,89	0,64	0,9	2,73	6,68	N	0,45	N	0,98	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6744	6744	G	C	MI.3672	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	841	281	G	R	Ggc/Cgc	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-2,55	deleterious	-5,55	high_impact	4,43	damaging	0,43	damaging	0,01	deleterious	3,9	23,5	0,11	0,55	disease	0,56	disease	0,95	disease	0,73	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,99	0,74	0,9	2,73	6,68	N	0,47	N	0,95	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6744	6744	G	A	MI.3673	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	841	281	G	S	Ggc/Agc	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-0,64	deleterious	-4,09	medium_impact	3,37	damaging	0,45	damaging	0,03	deleterious	4,16	23,8	0,21	0,55	neutral	0,29	disease	0,87	neutral	0,5	disease	0,5	0	deleterious	1	neutral	0	deleterious	5	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,01	0,73	0,9	2,73	6,68	N	0,35	N	0,73	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6745	6745	G	A	MI.3674	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	842	281	G	D	gGc/gAc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,68	deleterious	-3,5	deleterious	-4,86	high_impact	5,12	damaging	0,32	damaging	0,01	deleterious	3,82	23,4	0,14	0,55	disease	0,63	disease	0,93	disease	0,72	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,63	0,58	0,9	2,73	6,68	P	0,74	P	0,97	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6745	6745	G	T	MI.3675	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	842	281	G	V	gGc/gTc	6,14	1	0	probably_damaging	1	neutral	0,06	neutral	2,81	neutral	0,08	deleterious	-6,22	high_impact	3,63	damaging	0,46	damaging	0,02	deleterious	3,79	23,4	0,15	0,55	neutral	0,31	disease	0,94	disease	0,59	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,8	low_impact	-3,58	medium_impact	-0,47	high_impact	2,25	0,51	0,9	2,73	6,68	N	0,46	N	0,93	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6745	6745	G	C	MI.3676	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	842	281	G	A	gGc/gCc	6,14	1	0	probably_damaging	1	neutral	0,11	neutral	3	neutral	1,36	deleterious	-4,09	medium_impact	2,12	damaging	0,43	damaging	0,13	deleterious	3,04	22,4	0,3	0,55	neutral	0,2	disease	0,81	neutral	0,38	neutral	0,21	6	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,74	low_impact	-3,58	medium_impact	-0,31	medium_impact	0,86	0,74	0,9	2,73	6,68	P	0,55	P	0,64	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6747	6747	T	C	MI.3677	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	844	282	F	L	Ttc/Ctc	-20	0	0	probably_damaging	0,96	neutral	1	neutral	2,86	neutral	-0,47	neutral	0,99	neutral_impact	-0,94	neutral	0,62	neutral	0,43	neutral	-0,53	0,18	0,27	0,55	neutral	0,17	neutral	0,35	neutral	0,25	neutral	0,45	1	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,65	low_impact	-2,06	high_impact	1,86	low_impact	-1,97	0,75	0,9	2,53	7,37	N	0,27	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6747	6747	T	A	MI.3678	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	844	282	F	I	Ttc/Atc	-20	0	0	probably_damaging	0,98	neutral	0,37	neutral	2,76	neutral	-0,63	neutral	0,79	neutral_impact	-0,48	neutral	0,64	damaging	0,22	neutral	0,94	10,33	0,22	0,55	neutral	0,31	disease	0,65	neutral	0,25	neutral	0,36	3	neutral	0,98	neutral	0,2	neutral	-2	deleterious	0,71	low_impact	-2,35	medium_impact	0,06	low_impact	-1,54	0,59	0,9	2,53	7,37	N	0,32	N	0,88	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6747	6747	T	G	MI.3679	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	844	282	F	V	Ttc/Gtc	-20	0	0	probably_damaging	0,99	neutral	0,3	neutral	2,81	neutral	-0,26	neutral	0,39	neutral_impact	-0,04	neutral	0,7	damaging	0,26	neutral	0,98	10,53	0,28	0,55	neutral	0,21	disease	0,69	neutral	0,25	neutral	0,35	3	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,69	low_impact	-2,64	medium_impact	-0,01	low_impact	-1,14	0,59	0,9	2,53	7,37	N	0,34	N	0,84	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8699	8699	T	A	MI.368	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	173	58	M	K	aTa/aAa	0,36	0,03	0	probably_damaging	0,94	neutral	0,33	neutral	4,62	neutral	2,41	deleterious	-4,64	neutral_impact	0,69	neutral	0,77	neutral	0,41	deleterious	3,83	23,4	0,35	0,65	NA	NA	disease	0,73	neutral	0,4	disease	0,52	0	neutral	0,95	neutral	0,2	neutral	-2	deleterious	0,79	low_impact	-1,89	medium_impact	0,12	medium_impact	-0,51	0,59	0,9	40,71	8,78	N	0,27	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6748	6748	T	A	MI.3680	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	845	282	F	Y	tTc/tAc	4,29	1	0	probably_damaging	0,96	deleterious	0	neutral	2,62	neutral	-2,9	neutral	-0,76	medium_impact	2,63	neutral	0,63	damaging	0,11	deleterious	2,46	19,24	0,26	0,55	neutral	0,41	disease	0,78	neutral	0,46	disease	0,61	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,72	low_impact	-2,06	low_impact	-1,48	medium_impact	1,33	0,62	0,9	2,53	7,37	N	0,46	N	0,59	disease_causing	0,96	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6748	6748	T	G	MI.3681	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	845	282	F	C	tTc/tGc	4,29	1	0	probably_damaging	1	neutral	0,12	neutral	2,61	deleterious	-4,04	neutral	-1,22	low_impact	1,9	neutral	0,62	damaging	0,11	deleterious	4,03	23,6	0,22	0,55	disease	0,68	disease	0,88	disease	0,55	disease	0,76	5	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,79	low_impact	-3,58	medium_impact	-0,29	medium_impact	0,66	0,39	0,9	2,53	7,37	N	0,39	N	0,91	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6748	6748	T	C	MI.3682	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	845	282	F	S	tTc/tCc	4,29	1	0	probably_damaging	0,99	deleterious	0	neutral	2,66	neutral	-2,66	neutral	-1,44	medium_impact	2,42	neutral	0,7	damaging	0,14	deleterious	3,88	23,5	0,32	0,55	neutral	0,48	disease	0,76	disease	0,54	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-2,64	low_impact	-1,48	medium_impact	1,14	0,57	0,9	2,53	7,37	N	0,39	N	0,84	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6749	6749	C	G	MI.3683	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	846	282	F	L	ttC/ttG	5,91	1	0	probably_damaging	0,96	neutral	1	neutral	2,86	neutral	-0,47	neutral	0,99	neutral_impact	-0,94	neutral	0,62	neutral	0,43	neutral	-0,26	0,82	0,27	0,55	neutral	0,17	neutral	0,35	neutral	0,25	neutral	0,45	1	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,65	low_impact	-2,06	high_impact	1,86	low_impact	-1,97	0,75	0,9	2,53	7,37	N	0,47	N	0,83	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6749	6749	C	A	MI.3684	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	846	282	F	L	ttC/ttA	5,91	1	0	probably_damaging	0,96	neutral	1	neutral	2,86	neutral	-0,47	neutral	0,99	neutral_impact	-0,94	neutral	0,62	neutral	0,43	deleterious	0,07	3,28	0,27	0,55	neutral	0,17	neutral	0,35	neutral	0,25	neutral	0,45	1	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,65	low_impact	-2,06	high_impact	1,86	low_impact	-1,97	0,75	0,9	2,53	7,37	N	0,49	N	0,83	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6750	6750	C	G	MI.3685	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	847	283	L	V	Cta/Gta	-4,27	0	0	probably_damaging	0,99	deleterious	0	neutral	2,66	neutral	-0,88	neutral	-1,8	high_impact	3,73	damaging	0,42	damaging	0,08	deleterious	3,45	23	0,43	0,55	neutral	0,28	disease	0,74	neutral	0,45	neutral	0,49	0	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,64	low_impact	-1,48	high_impact	2,35	0,72	0,9	3,7	6,76	N	0,37	N	0,66	polymorphism	0,85	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6750	6750	C	A	MI.3686	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	847	283	L	M	Cta/Ata	-4,27	0	0	probably_damaging	1	deleterious	0,02	neutral	2,52	neutral	-2,82	neutral	-0,85	medium_impact	2,88	damaging	0,51	damaging	0,17	deleterious	3,71	23,3	0,27	0,55	disease	0,52	disease	0,64	disease	0,56	neutral	0,47	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,56	0,7	0,9	3,7	6,76	N	0,34	N	0,59	polymorphism	0,88	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6751	6751	T	C	MI.3687	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	848	283	L	P	cTa/cCa	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-4,67	deleterious	-4,64	high_impact	4,67	damaging	0,37	damaging	0,08	deleterious	3,94	23,5	0,17	0,55	disease	0,94	disease	0,89	disease	0,76	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,21	0,62	0,9	3,7	6,76	P	0,59	P	0,83	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6751	6751	T	A	MI.3688	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	848	283	L	Q	cTa/cAa	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-3,73	deleterious	-3,84	high_impact	4,88	damaging	0,46	damaging	0,08	deleterious	4,11	23,7	0,16	0,55	disease	0,93	disease	0,87	disease	0,65	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,41	0,66	0,9	3,7	6,76	P	0,61	P	0,82	disease_causing	0,89	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6751	6751	T	G	MI.3689	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	848	283	L	R	cTa/cGa	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-4,06	deleterious	-3,95	high_impact	5,22	damaging	0,45	damaging	0,07	deleterious	4,2	23,9	0,14	0,55	disease	0,93	disease	0,95	disease	0,76	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,58	low_impact	-1,48	high_impact	3,72	0,48	0,9	3,7	6,76	P	0,63	P	0,9	disease_causing	0,91	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8699	8699	T	C	MI.369	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	173	58	M	T	aTa/aCa	0,36	0,03	0	probably_damaging	0,94	neutral	0,4	neutral	4,42	neutral	0,51	deleterious	-4,26	low_impact	1,66	neutral	0,85	neutral	0,57	deleterious	2,84	21,6	0,55	0,65	NA	NA	disease	0,62	neutral	0,38	neutral	0,47	1	neutral	0,94	neutral	0,23	neutral	-2	deleterious	0,75	low_impact	-1,89	medium_impact	0,19	medium_impact	0,33	0,19	0,9	40,71	8,78	N	0,27	N	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6753	6753	G	T	MI.3690	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	850	284	G	W	Ggg/Tgg	-0,8	0,01	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-6,15	deleterious	-5,77	high_impact	5,25	damaging	0,42	damaging	0,02	deleterious	4,43	24,2	0,15	0,55	disease	0,92	disease	0,93	disease	0,74	disease	0,61	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,75	0,36	0,9	1,95	6,65	P	0,55	P	0,83	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6753	6753	G	C	MI.3691	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	850	284	G	R	Ggg/Cgg	-0,8	0,01	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-4,14	deleterious	-5,76	high_impact	4,7	damaging	0,44	damaging	0,02	deleterious	3,94	23,5	0,11	0,55	neutral	0,28	disease	0,93	disease	0,79	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,24	0,64	0,9	1,95	6,65	P	0,53	P	0,95	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6754	6754	G	A	MI.3692	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	851	284	G	E	gGg/gAg	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-3,81	deleterious	-5,76	high_impact	5,25	damaging	0,38	damaging	0,02	deleterious	4,01	23,6	0,15	0,55	disease	0,52	disease	0,9	disease	0,79	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,75	0,52	0,9	1,95	6,65	P	0,74	P	0,93	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6754	6754	G	T	MI.3693	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	851	284	G	V	gGg/gTg	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-3,38	deleterious	-6,48	high_impact	5,25	damaging	0,48	damaging	0,03	deleterious	3,84	23,4	0,14	0,55	disease	0,61	disease	0,92	disease	0,7	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,75	0,4	0,9	1,95	6,65	P	0,64	P	0,93	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6754	6754	G	C	MI.3694	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	851	284	G	A	gGg/gCg	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,61	neutral	-2,51	deleterious	-4,32	high_impact	4,7	damaging	0,58	damaging	0,04	deleterious	3,19	22,7	0,2	0,55	neutral	0,48	disease	0,79	disease	0,68	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	3,24	0,68	0,9	1,95	6,65	P	0,59	P	0,64	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6756	6756	T	C	MI.3695	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	853	285	F	L	Ttt/Ctt	-20	0	0	probably_damaging	0,99	deleterious	0	neutral	2,86	neutral	-1,37	deleterious	-4,3	high_impact	3,63	neutral	0,75	damaging	0,05	deleterious	4,21	23,9	0,3	0,55	neutral	0,45	disease	0,83	disease	0,58	disease	0,55	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	2,25	0,76	0,9	3,7	8,17	N	0,27	N	0,83	polymorphism	0,81	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6756	6756	T	G	MI.3696	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	853	285	F	V	Ttt/Gtt	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,83	neutral	-1,45	deleterious	-5,02	high_impact	3,58	neutral	0,72	damaging	0,07	deleterious	4,21	23,9	0,25	0,55	neutral	0,45	disease	0,92	disease	0,67	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,21	0,63	0,9	3,7	8,17	N	0,3	N	0,84	polymorphism	0,69	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6756	6756	T	A	MI.3697	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	853	285	F	I	Ttt/Att	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,92	neutral	-1,61	deleterious	-4,3	high_impact	3,67	neutral	0,74	damaging	0,07	deleterious	4,51	24,3	0,22	0,55	disease	0,53	disease	0,93	disease	0,65	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,29	0,64	0,9	3,7	8,17	N	0,3	N	0,88	polymorphism	0,83	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6757	6757	T	C	MI.3698	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	854	285	F	S	tTt/tCt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-2,78	deleterious	-5,74	medium_impact	3,35	neutral	0,75	damaging	0,08	deleterious	4,27	24	0,24	0,55	disease	0,58	disease	0,87	disease	0,65	disease	0,7	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	medium_impact	1,99	0,62	0,9	3,7	8,17	N	0,46	N	0,84	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6757	6757	T	A	MI.3699	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	854	285	F	Y	tTt/tAt	7,53	1	0	probably_damaging	0,99	deleterious	0,02	neutral	2,76	deleterious	-3,13	neutral	-2,15	high_impact	4,13	neutral	0,72	damaging	0,06	deleterious	4,27	23,9	0,29	0,55	disease	0,51	disease	0,86	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-2,64	medium_impact	-0,75	high_impact	2,71	0,71	0,9	3,7	8,17	P	0,53	P	0,59	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8542	8542	T	A	MI.37	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	16	6	F	I	Ttc/Atc	0,13	0,97	0	probably_damaging	0,95	deleterious	0	neutral	3,93	neutral	-1,13	deleterious	-5,08	medium_impact	3,32	neutral	0,66	neutral	0,68	deleterious	4,3	24	0,38	0,65	disease	0,78	disease	0,72	disease	0,8	disease	0,8	6	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,79	low_impact	-1,97	low_impact	-1,4	medium_impact	1,75	0,39	0,9	39,82	8,43	N	0,47	N	0,95	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8700	8700	A	T	MI.370	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	174	58	M	I	atA/atT	7,53	0,97	0	probably_damaging	0,91	neutral	0,39	neutral	4,37	neutral	-0,83	neutral	-2,25	low_impact	1,34	neutral	0,81	neutral	0,56	deleterious	3,24	22,8	0,75	0,8	NA	NA	disease	0,55	neutral	0,31	neutral	0,47	1	neutral	0,91	neutral	0,24	neutral	-2	deleterious	0,72	low_impact	-1,71	medium_impact	0,18	medium_impact	0,05	0,51	0,9	40,71	8,78	N	0,47	N	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6757	6757	T	G	MI.3700	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	854	285	F	C	tTt/tGt	7,53	1	0	probably_damaging	1	neutral	0,19	neutral	2,73	deleterious	-4,32	deleterious	-5,74	high_impact	3,63	neutral	0,74	damaging	0,06	deleterious	4,15	23,8	0,21	0,55	disease	0,62	disease	0,88	neutral	0,5	neutral	0,25	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,8	low_impact	-3,58	medium_impact	-0,16	high_impact	2,25	0,43	0,9	3,7	8,17	N	0,45	N	0,91	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6758	6758	T	G	MI.3701	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	855	285	F	L	ttT/ttG	5,91	1	0	probably_damaging	0,99	deleterious	0	neutral	2,86	neutral	-1,37	deleterious	-4,3	high_impact	3,63	neutral	0,75	damaging	0,05	deleterious	4,38	24,1	0,3	0,55	neutral	0,45	disease	0,83	disease	0,58	disease	0,55	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	2,25	0,76	0,9	3,7	8,17	P	0,53	P	0,83	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6758	6758	T	A	MI.3702	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	855	285	F	L	ttT/ttA	5,91	1	0	probably_damaging	0,99	deleterious	0	neutral	2,86	neutral	-1,37	deleterious	-4,3	high_impact	3,63	neutral	0,75	damaging	0,05	deleterious	4,5	24,3	0,3	0,55	neutral	0,45	disease	0,83	disease	0,58	disease	0,55	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	2,25	0,76	0,9	3,7	8,17	P	0,54	P	0,83	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6759	6759	A	G	MI.3703	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	856	286	I	V	Atc/Gtc	-2,65	0	0	possibly_damaging	0,84	neutral	0,36	neutral	2,93	neutral	-0,55	neutral	-0,11	neutral_impact	0,44	neutral	0,71	neutral	0,3	neutral	1,36	12,56	0,6	0,65	neutral	0,19	neutral	0,12	neutral	0,38	neutral	0,27	5	neutral	0,85	neutral	0,26	neutral	-3	deleterious	0,5	low_impact	-1,43	medium_impact	0,05	medium_impact	-0,69	0,7	0,9	3,31	6,76	N	0,39	N	0,23	disease_causing	0,96	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6759	6759	A	C	MI.3704	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	856	286	I	L	Atc/Ctc	-2,65	0	0	probably_damaging	0,94	neutral	0,05	neutral	3,02	neutral	0,11	neutral	-0,99	low_impact	1,51	neutral	0,62	damaging	0,2	deleterious	2,58	19,96	0,35	0,55	neutral	0,17	disease	0,55	neutral	0,37	neutral	0,23	5	deleterious	0,99	neutral	0,06	neutral	-2	deleterious	0,55	low_impact	-1,88	medium_impact	-0,52	medium_impact	0,3	0,78	0,9	3,31	6,76	N	0,39	N	0,61	disease_causing	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6759	6759	A	T	MI.3705	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	856	286	I	F	Atc/Ttc	-2,65	0	0	probably_damaging	0,99	deleterious	0	neutral	2,85	neutral	-1,64	deleterious	-2,6	medium_impact	2,75	neutral	0,61	damaging	0,1	deleterious	3,77	23,4	0,29	0,55	neutral	0,38	disease	0,79	neutral	0,43	neutral	0,46	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	medium_impact	1,44	0,8	0,9	3,31	6,76	N	0,28	N	0,85	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6760	6760	T	G	MI.3706	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	857	286	I	S	aTc/aGc	5,68	1	0	probably_damaging	1	neutral	0,05	neutral	2,83	neutral	-2,17	deleterious	-3,73	medium_impact	3,4	neutral	0,65	damaging	0,17	deleterious	4,27	24	0,28	0,55	neutral	0,45	disease	0,81	disease	0,61	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,76	low_impact	-3,58	medium_impact	-0,52	high_impact	2,04	0,56	0,9	3,31	6,76	P	0,49	N	0,62	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6760	6760	T	C	MI.3707	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	857	286	I	T	aTc/aCc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,84	neutral	-1,95	deleterious	-2,73	medium_impact	3,1	neutral	0,63	damaging	0,16	deleterious	3,45	23	0,44	0,55	neutral	0,18	disease	0,69	disease	0,59	disease	0,65	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,71	low_impact	-3,58	low_impact	-1,48	medium_impact	1,76	0,68	0,9	3,31	6,76	N	0,43	N	0,76	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6760	6760	T	A	MI.3708	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	857	286	I	N	aTc/aAc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,81	neutral	-2,57	deleterious	-4,45	high_impact	4,59	damaging	0,59	damaging	0,12	deleterious	4,38	24,1	0,25	0,55	disease	0,5	disease	0,81	disease	0,61	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	3,14	0,64	0,9	3,31	6,76	P	0,5	N	0,94	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6761	6761	C	A	MI.3709	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	858	286	I	M	atC/atA	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,82	neutral	-2,39	neutral	-1,45	medium_impact	3,15	neutral	0,65	damaging	0,17	deleterious	3,89	23,5	0,39	0,55	neutral	0,33	disease	0,56	neutral	0,4	neutral	0,38	2	deleterious	1	neutral	0	deleterious	5	deleterious	0,7	low_impact	-3,58	low_impact	-1,48	medium_impact	1,81	0,84	0,9	3,31	6,76	N	0,47	N	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8700	8700	A	C	MI.371	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	174	58	M	I	atA/atC	7,53	0,97	0	probably_damaging	0,91	neutral	0,39	neutral	4,37	neutral	-0,83	neutral	-2,25	low_impact	1,34	neutral	0,81	neutral	0,56	deleterious	3,19	22,7	0,75	0,8	NA	NA	disease	0,55	neutral	0,31	neutral	0,47	1	neutral	0,91	neutral	0,24	neutral	-2	deleterious	0,72	low_impact	-1,71	medium_impact	0,18	medium_impact	0,05	0,51	0,9	40,71	8,78	N	0,46	N	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6761	6761	C	G	MI.3710	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	858	286	I	M	atC/atG	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,82	neutral	-2,39	neutral	-1,45	medium_impact	3,15	neutral	0,65	damaging	0,17	deleterious	3,38	22,9	0,39	0,55	neutral	0,33	disease	0,56	neutral	0,4	neutral	0,38	2	deleterious	1	neutral	0	deleterious	5	deleterious	0,7	low_impact	-3,58	low_impact	-1,48	medium_impact	1,81	0,84	0,9	3,31	6,76	N	0,47	N	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6762	6762	G	C	MI.3711	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	859	287	V	L	Gtg/Ctg	-4,04	0	0	probably_damaging	0,97	deleterious	0	neutral	2,3	deleterious	-3,42	neutral	-2,14	high_impact	4,5	neutral	0,67	damaging	0,06	deleterious	3,56	23,1	0,31	0,55	disease	0,5	disease	0,79	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-2,18	low_impact	-1,48	high_impact	3,06	0,59	0,9	2,53	6,69	N	0,38	N	0,55	polymorphism	0,94	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6762	6762	G	T	MI.3712	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	859	287	V	L	Gtg/Ttg	-4,04	0	0	probably_damaging	0,97	deleterious	0	neutral	2,3	deleterious	-3,42	neutral	-2,14	high_impact	4,5	neutral	0,67	damaging	0,06	deleterious	3,71	23,3	0,31	0,55	disease	0,5	disease	0,79	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-2,18	low_impact	-1,48	high_impact	3,06	0,59	0,9	2,53	6,69	N	0,38	N	0,55	polymorphism	0,94	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6762	6762	G	A	MI.3713	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	859	287	V	M	Gtg/Atg	-4,04	0	0	probably_damaging	1	deleterious	0	neutral	2,21	deleterious	-5,39	neutral	-2,14	high_impact	5,3	neutral	0,67	damaging	0,08	deleterious	3,7	23,3	0,25	0,55	disease	0,84	disease	0,79	disease	0,68	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,73	0,9	2,53	6,69	P	0,65	P	0,82	polymorphism	0,94	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6763	6763	T	A	MI.3714	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	860	287	V	E	gTg/gAg	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,21	deleterious	-6,43	deleterious	-4,28	high_impact	5,3	neutral	0,64	damaging	0,09	deleterious	4,82	24,8	0,1	0,55	disease	0,91	disease	0,89	disease	0,78	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,8	0,47	0,9	2,53	6,69	P	0,72	P	0,84	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6763	6763	T	C	MI.3715	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	860	287	V	A	gTg/gCg	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,37	deleterious	-4,21	deleterious	-2,85	high_impact	4,95	neutral	0,66	damaging	0,13	deleterious	3,6	23,2	0,23	0,55	disease	0,76	disease	0,72	disease	0,61	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,47	0,42	0,9	2,53	6,69	P	0,73	P	0,47	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6763	6763	T	G	MI.3716	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	860	287	V	G	gTg/gGg	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,35	deleterious	-5,89	deleterious	-4,99	high_impact	4,95	neutral	0,64	damaging	0,12	deleterious	3,89	23,5	0,13	0,55	disease	0,9	disease	0,83	disease	0,67	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,47	0,51	0,9	2,53	6,69	P	0,68	P	0,71	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6765	6765	T	C	MI.3717	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	862	288	W	R	Tga/Cga	-4,27	0	0	probably_damaging	1	deleterious	0	neutral	2,65	deleterious	-4,38	deleterious	-9,77	high_impact	4,59	neutral	0,62	damaging	0,23	deleterious	3,61	23,2	0,2	0,55	disease	0,78	disease	0,95	disease	0,85	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,14	0,19	0,9	4,48	6,79	N	0,52	P	0,98	disease_causing	0,92	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6765	6765	T	G	MI.3718	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	862	288	W	G	Tga/Gga	-4,27	0	0	probably_damaging	1	deleterious	0	neutral	2,82	neutral	-2,18	deleterious	-9,07	high_impact	4,74	neutral	0,62	neutral	0,42	deleterious	3,93	23,5	0,17	0,55	disease	0,52	disease	0,89	disease	0,8	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,28	0,17	0,9	4,48	6,79	P	0,63	P	0,89	disease_causing	0,97	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6766	6766	G	T	MI.3719	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	863	288	W	L	tGa/tTa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,72	deleterious	-3,29	deleterious	-9,07	high_impact	4,25	neutral	0,63	neutral	0,37	deleterious	4,37	24,1	0,16	0,55	disease	0,77	disease	0,89	disease	0,78	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,83	0,16	0,9	4,48	6,79	P	0,58	P	0,95	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8701	8701	A	T	MI.372	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	175	59	T	S	Acc/Tcc	-1,72	0	0,71	benign	0,14	neutral	0,51	neutral	4,44	neutral	0,53	neutral	-0,64	neutral_impact	-0,26	neutral	0,9	neutral	0,98	neutral	-1,23	0,01	0,81	0,85	NA	NA	neutral	0,14	neutral	0,28	neutral	0,21	6	neutral	0,4	deleterious	0,69	neutral	-6	neutral	0,19	medium_impact	-0,01	medium_impact	0,3	low_impact	-1,32	0,83	0,9	24,34	15,68	N	0,42	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6766	6766	G	C	MI.3720	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	863	288	W	S	tGa/tCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,66	deleterious	-4,14	deleterious	-9,76	high_impact	5,29	neutral	0,7	neutral	0,41	deleterious	4,09	23,7	0,17	0,55	disease	0,75	disease	0,92	disease	0,8	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,14	0,9	4,48	6,79	P	0,63	P	0,89	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6767	6767	A	C	MI.3721	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	864	288	W	C	tgA/tgC	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-6,01	deleterious	-9,07	high_impact	5,29	neutral	0,6	damaging	0,24	deleterious	4,07	23,7	0,2	0,55	disease	0,93	disease	0,93	disease	0,83	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,22	0,9	4,48	6,79	P	0,62	P	0,88	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6767	6767	A	T	MI.3722	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	864	288	W	C	tgA/tgT	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-6,01	deleterious	-9,07	high_impact	5,29	neutral	0,6	damaging	0,24	deleterious	4,19	23,8	0,2	0,55	disease	0,93	disease	0,93	disease	0,83	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,22	0,9	4,48	6,79	P	0,62	P	0,88	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6768	6768	G	T	MI.3723	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	865	289	A	S	Gca/Tca	0,82	0,99	0	probably_damaging	1	deleterious	0	neutral	2,55	neutral	-2,54	neutral	-2,08	high_impact	3,71	neutral	0,65	damaging	0,07	deleterious	3,79	23,4	0,3	0,55	neutral	0,33	disease	0,76	neutral	0,4	neutral	0,21	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,33	0,88	0,9	2,53	6,62	N	0,39	N	0,64	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6768	6768	G	C	MI.3724	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	865	289	A	P	Gca/Cca	0,82	0,99	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-4,51	deleterious	-3,49	high_impact	4,81	damaging	0,55	damaging	0,06	deleterious	3,89	23,5	0,13	0,55	disease	0,66	disease	0,89	disease	0,74	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,34	0,84	0,9	2,53	6,62	P	0,68	P	0,85	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6768	6768	G	A	MI.3725	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	865	289	A	T	Gca/Aca	0,82	0,99	0	probably_damaging	1	deleterious	0	neutral	2,57	neutral	-2,24	deleterious	-2,78	high_impact	5,16	neutral	0,62	damaging	0,07	deleterious	4,24	23,9	0,28	0,55	neutral	0,36	disease	0,86	disease	0,63	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,77	0,9	2,53	6,62	P	0,66	P	0,2	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6769	6769	C	T	MI.3726	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	866	289	A	V	gCa/gTa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,68	neutral	-0,79	deleterious	-2,79	high_impact	3,96	neutral	0,61	damaging	0,06	deleterious	4,44	24,2	0,27	0,55	neutral	0,24	disease	0,9	disease	0,63	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,56	0,75	0,9	2,53	6,62	P	0,51	P	0,75	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6769	6769	C	G	MI.3727	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	866	289	A	G	gCa/gGa	7,53	1	0	probably_damaging	0,99	neutral	0,17	neutral	2,73	neutral	-0,42	deleterious	-2,77	medium_impact	2,14	neutral	0,64	damaging	0,07	deleterious	3,93	23,5	0,24	0,55	neutral	0,31	disease	0,71	neutral	0,37	neutral	0,21	6	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,77	low_impact	-2,64	medium_impact	-0,19	medium_impact	0,88	0,86	0,9	2,53	6,62	N	0,47	N	0,56	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6769	6769	C	A	MI.3728	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	866	289	A	E	gCa/gAa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-3,83	deleterious	-3,48	high_impact	5,16	neutral	0,6	damaging	0,07	deleterious	4,53	24,3	0,12	0,55	neutral	0,48	disease	0,92	disease	0,72	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,76	0,9	2,53	6,62	P	0,72	P	0,76	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6771	6771	C	G	MI.3729	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	868	290	H	D	Cac/Gac	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	1,09	deleterious	-7,42	deleterious	-6,26	high_impact	5,29	damaging	0,52	damaging	0,04	deleterious	3,92	23,5	0,21	0,55	disease	0,62	disease	0,88	disease	0,83	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,57	0,9	2,14	7,15	P	0,53	P	0,97	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8701	8701	A	C	MI.373	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	175	59	T	P	Acc/Ccc	-1,72	0	0,71	possibly_damaging	0,48	neutral	0,24	neutral	4,3	neutral	-2,24	neutral	-2,35	low_impact	1,54	neutral	0,85	neutral	0,52	deleterious	0,45	7,08	0,4	0,65	NA	NA	disease	0,63	disease	0,57	disease	0,67	3	neutral	0,73	neutral	0,38	neutral	-3	deleterious	0,58	medium_impact	-0,72	medium_impact	0,01	medium_impact	0,22	0,72	0,9	24,34	15,68	N	0,3	N	0,74	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6771	6771	C	A	MI.3730	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	868	290	H	N	Cac/Aac	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	1,09	deleterious	-7,46	deleterious	-4,87	high_impact	5,29	damaging	0,57	damaging	0,04	deleterious	3,98	23,6	0,35	0,55	disease	0,81	disease	0,87	disease	0,81	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,61	0,9	2,14	7,15	P	0,62	P	0,86	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6771	6771	C	T	MI.3731	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	868	290	H	Y	Cac/Tac	-2,42	0	0	probably_damaging	1	deleterious	0	neutral	1,08	deleterious	-7,68	deleterious	-4,17	high_impact	4,95	damaging	0,6	damaging	0,04	deleterious	3,8	23,4	0,33	0,55	disease	0,89	disease	0,92	disease	0,81	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,47	0,52	0,9	2,14	7,15	P	0,64	P	0,72	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6772	6772	A	G	MI.3732	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	869	290	H	R	cAc/cGc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	1,09	deleterious	-7,14	deleterious	-5,57	high_impact	4,74	neutral	0,61	damaging	0,04	deleterious	2,92	21,9	0,35	0,55	disease	0,86	disease	0,93	disease	0,8	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,28	0,44	0,9	2,14	7,15	P	0,65	P	0,85	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6772	6772	A	C	MI.3733	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	869	290	H	P	cAc/cCc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	1,08	deleterious	-8,22	deleterious	-6,95	high_impact	4,59	damaging	0,51	damaging	0,05	deleterious	3,17	22,7	0,2	0,55	disease	0,91	disease	0,9	disease	0,87	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,14	0,5	0,9	2,14	7,15	P	0,52	P	0,9	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6772	6772	A	T	MI.3734	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	869	290	H	L	cAc/cTc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	1,09	deleterious	-7,22	deleterious	-7,64	high_impact	5,29	neutral	0,66	damaging	0,03	deleterious	3,74	23,3	0,19	0,55	disease	0,9	disease	0,92	disease	0,8	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,4	0,9	2,14	7,15	P	0,65	P	0,92	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6773	6773	C	A	MI.3735	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	870	290	H	Q	caC/caA	7,07	1	0	probably_damaging	1	deleterious	0	neutral	1,08	deleterious	-7,61	deleterious	-5,56	high_impact	5,29	neutral	0,63	damaging	0,04	deleterious	3,95	23,6	0,36	0,55	disease	0,84	disease	0,85	disease	0,81	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,56	0,9	2,14	7,15	P	0,66	P	0,83	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6773	6773	C	G	MI.3736	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	870	290	H	Q	caC/caG	7,07	1	0	probably_damaging	1	deleterious	0	neutral	1,08	deleterious	-7,61	deleterious	-5,56	high_impact	5,29	neutral	0,63	damaging	0,04	deleterious	3,61	23,2	0,36	0,55	disease	0,84	disease	0,85	disease	0,81	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,56	0,9	2,14	7,15	P	0,66	P	0,83	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6774	6774	C	A	MI.3737	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	871	291	H	N	Cat/Aat	-4,5	0	0	probably_damaging	0,98	deleterious	0	neutral	0,57	deleterious	-9,08	deleterious	-4,78	high_impact	5,28	damaging	0,55	damaging	0,04	deleterious	4,12	23,8	0,25	0,55	disease	0,82	disease	0,87	disease	0,81	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,35	low_impact	-1,48	high_impact	3,78	0,59	0,9	2,73	6,78	P	0,57	P	0,86	disease_causing	0,94	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6774	6774	C	T	MI.3738	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	871	291	H	Y	Cat/Tat	-4,5	0	0	probably_damaging	0,98	deleterious	0	neutral	0,65	deleterious	-5,86	deleterious	-4,09	high_impact	4,73	damaging	0,56	damaging	0,03	deleterious	3,72	23,3	0,26	0,55	disease	0,87	disease	0,91	disease	0,82	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-2,35	low_impact	-1,48	high_impact	3,27	0,58	0,9	2,73	6,78	P	0,62	P	0,72	disease_causing	0,95	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6774	6774	C	G	MI.3739	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	871	291	H	D	Cat/Gat	-4,5	0	0	probably_damaging	0,99	deleterious	0	neutral	0,57	deleterious	-9,16	deleterious	-6,14	high_impact	4,59	damaging	0,49	damaging	0,04	deleterious	3,88	23,5	0,18	0,55	disease	0,78	disease	0,88	disease	0,86	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,64	low_impact	-1,48	high_impact	3,14	0,53	0,9	2,73	6,78	N	0,42	N	0,97	disease_causing	0,98	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8701	8701	A	G	MI.374	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	175	59	T	A	Acc/Gcc	-1,72	0	0,71	benign	0,01	neutral	0,6	neutral	4,37	neutral	-0,27	neutral	-0,94	neutral_impact	0,36	neutral	0,98	neutral	0,98	neutral	-0,66	0,09	0,73	0,75	NA	NA	neutral	0,18	neutral	0,38	neutral	0,22	6	neutral	0,39	deleterious	0,8	neutral	-6	neutral	0,07	medium_impact	1,14	medium_impact	0,39	medium_impact	-0,79	0,36	0,9	24,34	15,68	N	0,29	N	0,03	polymorphism	1	0,02	rs2000975	.	.	.	.	thyroid tumors	.	.	.	.	.	.	.	.	.
chrM	6775	6775	A	C	MI.3740	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	872	291	H	P	cAt/cCt	7,3	1	0	probably_damaging	0,99	deleterious	0	neutral	0,57	deleterious	-10,12	deleterious	-6,82	high_impact	4,59	damaging	0,49	damaging	0,04	deleterious	3,31	22,9	0,18	0,55	disease	0,9	disease	0,9	disease	0,86	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,92	low_impact	-2,64	low_impact	-1,48	high_impact	3,14	0,55	0,9	2,73	6,78	P	0,5	N	0,9	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6775	6775	A	T	MI.3741	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	872	291	H	L	cAt/cTt	7,3	1	0	probably_damaging	0,98	deleterious	0	neutral	0,58	deleterious	-8,16	deleterious	-7,5	high_impact	5,28	neutral	0,68	damaging	0,03	deleterious	3,96	23,6	0,14	0,55	disease	0,86	disease	0,92	disease	0,79	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,35	low_impact	-1,48	high_impact	3,78	0,51	0,9	2,73	6,78	P	0,62	P	0,92	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6775	6775	A	G	MI.3742	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	872	291	H	R	cAt/cGt	7,3	1	0	probably_damaging	0,98	deleterious	0	neutral	0,58	deleterious	-8,74	deleterious	-5,46	high_impact	5,28	damaging	0,57	damaging	0,04	deleterious	3,08	22,5	0,28	0,55	disease	0,7	disease	0,93	disease	0,83	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,35	low_impact	-1,48	high_impact	3,78	0,55	0,9	2,73	6,78	P	0,59	P	0,85	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6776	6776	T	A	MI.3743	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	873	291	H	Q	caT/caA	8,69	1	0,1	probably_damaging	0,99	deleterious	0	neutral	0,57	deleterious	-9,16	deleterious	-5,46	high_impact	5,28	neutral	0,62	damaging	0,04	deleterious	3,71	23,3	0,25	0,55	disease	0,8	disease	0,85	disease	0,8	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,64	low_impact	-1,48	high_impact	3,78	0,61	0,9	2,73	6,78	P	0,65	P	0,83	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6776	6776	T	G	MI.3744	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	873	291	H	Q	caT/caG	8,69	1	0,1	probably_damaging	0,99	deleterious	0	neutral	0,57	deleterious	-9,16	deleterious	-5,46	high_impact	5,28	neutral	0,62	damaging	0,04	deleterious	3,62	23,2	0,25	0,55	disease	0,8	disease	0,85	disease	0,8	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,64	low_impact	-1,48	high_impact	3,78	0,61	0,9	2,73	6,78	P	0,65	P	0,83	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6777	6777	A	G	MI.3745	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	874	292	M	V	Ata/Gta	-4,5	0	0	probably_damaging	0,97	deleterious	0	neutral	2,61	neutral	-2,14	deleterious	-2,73	high_impact	5,28	neutral	0,61	damaging	0,05	deleterious	2,65	20,5	0,4	0,55	disease	0,54	disease	0,91	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-2,18	low_impact	-1,48	high_impact	3,78	0,55	0,9	2,73	6,76	P	0,59	P	0,88	polymorphism	0,74	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6777	6777	A	T	MI.3746	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	874	292	M	L	Ata/Tta	-4,5	0	0	probably_damaging	0,95	deleterious	0	neutral	2,79	neutral	-0,87	neutral	-2,05	high_impact	4,38	neutral	0,66	damaging	0,04	deleterious	3,29	22,8	0,39	0,55	neutral	0,33	disease	0,86	disease	0,67	disease	0,58	2	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,78	low_impact	-1,96	low_impact	-1,48	high_impact	2,95	0,49	0,9	2,73	6,76	N	0,39	N	0,61	polymorphism	0,78	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6777	6777	A	C	MI.3747	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	874	292	M	L	Ata/Cta	-4,5	0	0	probably_damaging	0,95	deleterious	0	neutral	2,79	neutral	-0,87	neutral	-2,05	high_impact	4,38	neutral	0,66	damaging	0,04	deleterious	3,19	22,7	0,39	0,55	neutral	0,33	disease	0,86	disease	0,67	disease	0,58	2	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,78	low_impact	-1,96	low_impact	-1,48	high_impact	2,95	0,49	0,9	2,73	6,76	N	0,39	N	0,61	polymorphism	0,78	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6778	6778	T	C	MI.3748	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	875	292	M	T	aTa/aCa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-3,14	deleterious	-4,09	high_impact	4,93	neutral	0,66	damaging	0,06	deleterious	3,01	22,3	0,37	0,55	disease	0,7	disease	0,91	disease	0,74	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,41	0,9	2,73	6,76	P	0,73	P	0,79	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6778	6778	T	A	MI.3749	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	875	292	M	K	aTa/aAa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-4,31	deleterious	-4,09	high_impact	5,28	neutral	0,61	damaging	0,03	deleterious	4,01	23,6	0,17	0,55	disease	0,77	disease	0,94	disease	0,82	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,37	0,9	2,73	6,76	P	0,75	P	0,93	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8702	8702	C	G	MI.375	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	176	59	T	S	aCc/aGc	-7,51	0	0,01	benign	0,14	neutral	0,51	neutral	4,44	neutral	0,53	neutral	-0,64	neutral_impact	-0,26	neutral	0,9	neutral	0,98	neutral	-1,05	0,01	0,81	0,85	NA	NA	neutral	0,14	neutral	0,28	neutral	0,21	6	neutral	0,4	deleterious	0,69	neutral	-6	neutral	0,19	medium_impact	-0,01	medium_impact	0,3	low_impact	-1,32	0,83	0,9	24,34	15,68	N	0,37	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6779	6779	A	C	MI.3750	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	876	292	M	I	atA/atC	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,6	neutral	-2,3	deleterious	-2,73	high_impact	4,58	damaging	0,55	damaging	0,06	deleterious	3,44	23	0,38	0,55	disease	0,52	disease	0,92	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,35	low_impact	-1,48	high_impact	3,13	0,63	0,9	2,73	6,76	P	0,53	P	0,87	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6779	6779	A	T	MI.3751	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	876	292	M	I	atA/atT	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,6	neutral	-2,3	deleterious	-2,73	high_impact	4,58	damaging	0,55	damaging	0,06	deleterious	3,46	23	0,38	0,55	disease	0,52	disease	0,92	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,35	low_impact	-1,48	high_impact	3,13	0,63	0,9	2,73	6,76	P	0,55	P	0,87	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6780	6780	T	C	MI.3752	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	877	293	F	L	Ttt/Ctt	-0,8	0	0	probably_damaging	1	deleterious	0	neutral	2,59	neutral	-2,49	deleterious	-4,07	high_impact	4,63	damaging	0,52	damaging	0,14	deleterious	4,08	23,7	0,38	0,55	disease	0,77	disease	0,85	disease	0,62	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,18	0,87	0,9	2,73	6,71	N	0,46	N	0,83	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6780	6780	T	G	MI.3753	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	877	293	F	V	Ttt/Gtt	-0,8	0	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-3,43	deleterious	-4,74	high_impact	4,84	damaging	0,52	damaging	0,11	deleterious	4,03	23,7	0,28	0,55	disease	0,88	disease	0,94	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,67	0,9	2,73	6,71	P	0,62	P	0,84	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6780	6780	T	A	MI.3754	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	877	293	F	I	Ttt/Att	-0,8	0	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-3,89	deleterious	-4,07	high_impact	4,03	damaging	0,59	damaging	0,14	deleterious	4,42	24,2	0,22	0,55	disease	0,88	disease	0,92	disease	0,64	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	2,62	0,72	0,9	2,73	6,71	N	0,32	N	0,88	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6781	6781	T	A	MI.3755	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	878	293	F	Y	tTt/tAt	4,76	1	0	probably_damaging	1	neutral	0,17	neutral	2,62	neutral	-1,68	neutral	-1,99	medium_impact	2,47	damaging	0,57	damaging	0,12	deleterious	4,36	24,1	0,29	0,55	neutral	0,36	disease	0,74	neutral	0,45	neutral	0,36	3	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,79	low_impact	-3,58	medium_impact	-0,19	medium_impact	1,18	0,8	0,9	2,73	6,71	P	0,5	N	0,59	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6781	6781	T	G	MI.3756	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	878	293	F	C	tTt/tGt	4,76	1	0	probably_damaging	1	deleterious	0	neutral	2,43	deleterious	-6,31	deleterious	-5,43	high_impact	5,18	damaging	0,54	damaging	0,12	deleterious	4,15	23,8	0,23	0,55	disease	0,97	disease	0,93	disease	0,72	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,43	0,9	2,73	6,71	P	0,62	P	0,91	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6781	6781	T	C	MI.3757	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	878	293	F	S	tTt/tCt	4,76	1	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-4,91	deleterious	-5,42	high_impact	4,49	neutral	0,64	damaging	0,15	deleterious	4,36	24,1	0,24	0,55	disease	0,92	disease	0,91	disease	0,7	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,05	0,6	0,9	2,73	6,71	P	0,52	P	0,84	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6782	6782	T	A	MI.3758	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	879	293	F	L	ttT/ttA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,59	neutral	-2,49	deleterious	-4,07	high_impact	4,63	damaging	0,52	damaging	0,14	deleterious	4,5	24,3	0,38	0,55	disease	0,77	disease	0,85	disease	0,62	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,18	0,87	0,9	2,73	6,71	P	0,62	P	0,83	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6782	6782	T	G	MI.3759	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	879	293	F	L	ttT/ttG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,59	neutral	-2,49	deleterious	-4,07	high_impact	4,63	damaging	0,52	damaging	0,14	deleterious	4,38	24,1	0,38	0,55	disease	0,77	disease	0,85	disease	0,62	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,18	0,87	0,9	2,73	6,71	P	0,61	P	0,83	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8702	8702	C	A	MI.376	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	176	59	T	N	aCc/aAc	-7,51	0	0,01	possibly_damaging	0,56	neutral	0,39	neutral	4,37	neutral	-0,36	neutral	-1,92	low_impact	0,9	neutral	0,89	neutral	0,83	neutral	1,67	14,21	0,78	0,8	NA	NA	neutral	0,31	neutral	0,29	neutral	0,15	7	neutral	0,62	neutral	0,42	neutral	-3	deleterious	0,54	medium_impact	-0,86	medium_impact	0,18	medium_impact	-0,33	0,77	0,9	24,34	15,68	N	0,42	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6783	6783	A	C	MI.3760	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	880	294	T	P	Aca/Cca	-2,19	0	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-4,49	deleterious	-3,65	high_impact	5,16	neutral	0,63	damaging	0,14	deleterious	3,58	23,2	0,14	0,55	disease	0,82	disease	0,86	disease	0,61	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,68	0,9	1,95	6,72	P	0,68	P	0,92	disease_causing	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6783	6783	A	T	MI.3761	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	880	294	T	S	Aca/Tca	-2,19	0	0	probably_damaging	0,98	deleterious	0,04	neutral	2,55	neutral	-2,52	neutral	-2	medium_impact	3,04	neutral	0,77	damaging	0,16	deleterious	3,35	22,9	0,47	0,55	disease	0,63	disease	0,73	neutral	0,48	neutral	0,48	0	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,79	low_impact	-2,35	medium_impact	-0,58	medium_impact	1,71	0,72	0,9	1,95	6,72	N	0,28	N	0,79	disease_causing	0,9	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6783	6783	A	G	MI.3762	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	880	294	T	A	Aca/Gca	-2,19	0	0	probably_damaging	0,98	deleterious	0	neutral	2,59	neutral	-1,75	deleterious	-2,87	medium_impact	3,24	neutral	0,64	damaging	0,16	deleterious	3,54	23,1	0,58	0,65	neutral	0,46	disease	0,76	disease	0,52	disease	0,55	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-2,35	low_impact	-1,48	medium_impact	1,89	0,69	0,9	1,95	6,72	N	0,33	N	0,69	disease_causing	0,96	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6784	6784	C	A	MI.3763	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	881	294	T	K	aCa/aAa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-3,61	deleterious	-3,56	high_impact	5,16	neutral	0,67	damaging	0,1	deleterious	4,46	24,2	0,2	0,55	disease	0,7	disease	0,91	disease	0,74	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,73	0,9	1,95	6,72	P	0,75	P	0,88	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6784	6784	C	T	MI.3764	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	881	294	T	M	aCa/aTa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,55	neutral	-2,73	deleterious	-3,66	high_impact	3,91	neutral	0,77	damaging	0,12	deleterious	4,07	23,7	0,39	0,55	disease	0,72	disease	0,84	disease	0,52	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,51	0,76	0,9	1,95	6,72	N	0,44	N	0,96	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6786	6786	G	C	MI.3765	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	883	295	V	L	Gta/Cta	-7,97	0	0	probably_damaging	0,99	deleterious	0	neutral	2,73	neutral	-0,8	neutral	-1,86	high_impact	5,07	neutral	0,63	damaging	0,12	deleterious	3,67	23,3	0,4	0,55	neutral	0,41	disease	0,82	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	3,58	0,77	0,9	2,92	7,3	P	0,67	P	0,55	polymorphism	0,94	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6786	6786	G	A	MI.3766	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	883	295	V	M	Gta/Ata	-7,97	0	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-1,06	neutral	-1,94	high_impact	3,92	neutral	0,66	damaging	0,15	deleterious	3,8	23,4	0,34	0,55	neutral	0,41	disease	0,82	disease	0,52	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,52	0,77	0,9	2,92	7,3	N	0,35	N	0,82	polymorphism	0,94	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6786	6786	G	T	MI.3767	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	883	295	V	L	Gta/Tta	-7,97	0	0	probably_damaging	0,99	deleterious	0	neutral	2,73	neutral	-0,8	neutral	-1,86	high_impact	5,07	neutral	0,63	damaging	0,12	deleterious	3,78	23,4	0,4	0,55	neutral	0,41	disease	0,82	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	3,58	0,77	0,9	2,92	7,3	P	0,67	P	0,55	polymorphism	0,94	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6787	6787	T	G	MI.3768	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	884	295	V	G	gTa/gGa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-1,09	deleterious	-4,73	high_impact	4,72	damaging	0,52	damaging	0,17	deleterious	3,94	23,5	0,15	0,55	disease	0,61	disease	0,89	disease	0,68	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,26	0,53	0,9	2,92	7,3	P	0,7	P	0,71	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6787	6787	T	C	MI.3769	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	884	295	V	A	gTa/gCa	9,15	1	0	probably_damaging	1	deleterious	0,04	neutral	2,76	neutral	-0,45	deleterious	-2,69	high_impact	3,75	damaging	0,53	damaging	0,18	deleterious	3,69	23,3	0,37	0,55	neutral	0,36	disease	0,76	disease	0,57	disease	0,55	1	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,77	low_impact	-3,58	medium_impact	-0,58	high_impact	2,36	0,56	0,9	2,92	7,3	P	0,52	P	0,47	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8702	8702	C	T	MI.377	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	176	59	T	I	aCc/aTc	-7,51	0	0,01	benign	0,01	neutral	0,42	neutral	4,3	neutral	-2,41	neutral	-1,02	neutral_impact	0,79	neutral	0,93	neutral	0,96	deleterious	0,29	5,56	0,58	0,7	NA	NA	neutral	0,3	neutral	0,33	neutral	0,14	7	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,11	medium_impact	1,14	medium_impact	0,21	medium_impact	-0,42	0,46	0,9	24,34	15,68	N	0,35	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6787	6787	T	A	MI.3770	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	884	295	V	E	gTa/gAa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,65	neutral	-2,72	deleterious	-4,05	high_impact	5,07	neutral	0,63	damaging	0,15	deleterious	5,02	25,2	0,09	0,55	neutral	0,45	disease	0,92	disease	0,77	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,58	0,42	0,9	2,92	7,3	P	0,75	P	0,84	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6789	6789	G	C	MI.3771	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	886	296	G	R	Gga/Cga	-3,8	0	0	probably_damaging	1	deleterious	0	neutral	2,02	deleterious	-5,11	deleterious	-5,39	high_impact	4,93	neutral	0,68	damaging	0,08	deleterious	4,02	23,6	0,14	0,55	disease	0,74	disease	0,91	disease	0,82	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,76	0,9	2,92	6,67	P	0,66	P	0,95	disease_causing	0,83	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6789	6789	G	T	MI.3772	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	886	296	G	W	Gga/Tga	-3,8	0	0	probably_damaging	1	deleterious	0	neutral	1,99	deleterious	-8,55	deleterious	-5,41	high_impact	5,28	neutral	0,68	damaging	0,09	deleterious	4,47	24,2	0,14	0,55	disease	0,94	disease	0,91	disease	0,77	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,33	0,9	2,92	6,67	P	0,6	P	0,83	disease_causing	0,89	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6790	6790	G	A	MI.3773	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	887	296	G	E	gGa/gAa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,05	deleterious	-4,06	deleterious	-5,36	high_impact	5,28	damaging	0,58	damaging	0,13	deleterious	4	23,6	0,16	0,55	disease	0,7	disease	0,89	disease	0,82	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,69	0,9	2,92	6,67	P	0,75	P	0,93	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6790	6790	G	T	MI.3774	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	887	296	G	V	gGa/gTa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,03	deleterious	-4,82	deleterious	-6,07	high_impact	4,59	neutral	0,64	damaging	0,09	deleterious	3,85	23,4	0,13	0,55	disease	0,65	disease	0,91	disease	0,72	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,14	0,5	0,9	2,92	6,67	N	0,5	N	0,93	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6790	6790	G	C	MI.3775	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	887	296	G	A	gGa/gCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,05	deleterious	-4,09	deleterious	-4,04	high_impact	4,93	neutral	0,74	damaging	0,14	deleterious	3,22	22,7	0,22	0,55	disease	0,57	disease	0,78	disease	0,67	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,68	0,9	2,92	6,67	P	0,71	P	0,64	disease_causing	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6792	6792	A	G	MI.3776	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	889	297	M	V	Ata/Gta	-7,74	0	0	possibly_damaging	0,89	deleterious	0	neutral	2,98	neutral	-0,72	neutral	-2,41	high_impact	4,39	neutral	0,62	damaging	0,12	deleterious	2,85	21,6	0,45	0,55	neutral	0,22	disease	0,88	disease	0,58	disease	0,69	4	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,7	low_impact	-1,61	low_impact	-1,48	high_impact	2,95	0,43	0,9	8,38	36,17	N	0,34	N	0,46	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6792	6792	A	C	MI.3777	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	889	297	M	L	Ata/Cta	-7,74	0	0	possibly_damaging	0,84	neutral	0,36	neutral	3,14	neutral	0,29	neutral	-1,6	low_impact	1,32	neutral	0,64	neutral	0,89	deleterious	2,14	17,14	0,48	0,55	neutral	0,22	disease	0,59	neutral	0,28	neutral	0,41	2	neutral	0,85	neutral	0,26	neutral	-3	deleterious	0,57	low_impact	-1,43	medium_impact	0,05	medium_impact	0,12	0,48	0,9	8,38	36,17	N	0,43	N	0	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6792	6792	A	T	MI.3778	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	889	297	M	L	Ata/Tta	-7,74	0	0	possibly_damaging	0,84	neutral	0,36	neutral	3,14	neutral	0,29	neutral	-1,6	low_impact	1,32	neutral	0,64	neutral	0,89	deleterious	2,25	17,83	0,48	0,55	neutral	0,22	disease	0,59	neutral	0,28	neutral	0,41	2	neutral	0,85	neutral	0,26	neutral	-3	deleterious	0,57	low_impact	-1,43	medium_impact	0,05	medium_impact	0,12	0,48	0,9	8,38	36,17	N	0,43	N	0	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6793	6793	T	C	MI.3779	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	890	297	M	T	aTa/aCa	1,98	0,87	0	probably_damaging	0,98	deleterious	0	neutral	2,93	neutral	-1,55	deleterious	-3,72	high_impact	3,9	neutral	0,67	damaging	0,17	deleterious	3,11	22,5	0,44	0,55	neutral	0,27	disease	0,9	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,35	low_impact	-1,48	high_impact	2,5	0,24	0,9	8,38	36,17	N	0,34	N	0,61	polymorphism	0,9	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8704	8704	A	G	MI.378	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	178	60	M	V	Ata/Gta	-9,59	0	0	benign	0	neutral	0,55	neutral	4,48	neutral	1,62	neutral	0,03	neutral_impact	0,24	neutral	0,99	neutral	0,94	neutral	-0,61	0,12	0,84	0,85	NA	NA	neutral	0,37	disease	0,52	neutral	0,32	4	neutral	0,45	deleterious	0,78	neutral	-6	neutral	0,15	high_impact	2,09	medium_impact	0,34	medium_impact	-0,89	0,43	0,9	26,99	19,59	N	0,37	N	0,3	polymorphism	1	0,01	rs878852994	Uncertain significance	not_provided	RCV000224912.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	6793	6793	T	A	MI.3780	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	890	297	M	K	aTa/aAa	1,98	0,87	0	probably_damaging	0,95	deleterious	0	neutral	2,85	deleterious	-3,18	deleterious	-3,8	high_impact	4,39	neutral	0,62	damaging	0,1	deleterious	4,36	24,1	0,21	0,55	neutral	0,44	disease	0,93	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,84	low_impact	-1,96	low_impact	-1,48	high_impact	2,95	0,33	0,9	8,38	36,17	N	0,47	N	0,73	polymorphism	0,54	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6794	6794	A	T	MI.3781	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	891	297	M	I	atA/atT	4,76	0,97	0	probably_damaging	0,92	deleterious	0	neutral	2,95	neutral	-0,02	neutral	-2,33	medium_impact	3,42	neutral	0,63	damaging	0,13	deleterious	3,59	23,2	0,53	0,6	neutral	0,24	disease	0,89	neutral	0,38	disease	0,63	3	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,75	low_impact	-1,76	low_impact	-1,48	high_impact	2,06	0,56	0,9	8,38	36,17	N	0,46	N	0,31	disease_causing	0,94	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6794	6794	A	C	MI.3782	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	891	297	M	I	atA/atC	4,76	0,97	0	probably_damaging	0,92	deleterious	0	neutral	2,95	neutral	-0,02	neutral	-2,33	medium_impact	3,42	neutral	0,63	damaging	0,13	deleterious	3,45	23	0,53	0,6	neutral	0,24	disease	0,89	neutral	0,38	disease	0,63	3	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,75	low_impact	-1,76	low_impact	-1,48	high_impact	2,06	0,56	0,9	8,38	36,17	N	0,46	N	0,31	disease_causing	0,94	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6795	6795	G	T	MI.3783	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	892	298	D	Y	Gac/Tac	-0,33	0,23	0	probably_damaging	1	deleterious	0	neutral	2,69	deleterious	-4,24	deleterious	-5,83	high_impact	5,17	damaging	0,58	damaging	0,05	deleterious	3,97	23,6	0,25	0,55	disease	0,67	disease	0,95	disease	0,66	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,37	0,9	2,34	6,69	P	0,56	P	0,94	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6795	6795	G	A	MI.3784	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	892	298	D	N	Gac/Aac	-0,33	0,23	0	probably_damaging	0,99	deleterious	0,04	neutral	2,77	neutral	-1,87	deleterious	-3,19	medium_impact	3,08	damaging	0,54	damaging	0,12	deleterious	4,25	23,9	0,61	0,65	neutral	0,41	disease	0,83	neutral	0,27	neutral	0,45	1	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,81	low_impact	-2,64	medium_impact	-0,58	medium_impact	1,75	0,87	0,9	2,34	6,69	N	0,32	N	0,89	disease_causing	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6795	6795	G	C	MI.3785	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	892	298	D	H	Gac/Cac	-0,33	0,23	0	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-3,34	deleterious	-4,5	high_impact	4,82	damaging	0,58	damaging	0,04	deleterious	3,7	23,3	0,35	0,55	disease	0,58	disease	0,89	disease	0,65	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,35	0,61	0,9	2,34	6,69	P	0,6	P	0,97	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6796	6796	A	G	MI.3786	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	893	298	D	G	gAc/gGc	6,38	1	0	probably_damaging	0,99	deleterious	0	neutral	2,8	neutral	-1,41	deleterious	-4,54	high_impact	4,62	damaging	0,58	damaging	0,06	deleterious	4,05	23,7	0,26	0,55	neutral	0,35	disease	0,92	disease	0,62	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,64	low_impact	-1,48	high_impact	3,17	0,39	0,9	2,34	6,69	P	0,47	N	0,85	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6796	6796	A	C	MI.3787	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	893	298	D	A	gAc/gCc	6,38	1	0	probably_damaging	0,99	deleterious	0	neutral	2,73	neutral	-2,67	deleterious	-5,17	high_impact	4,82	neutral	0,62	damaging	0,07	deleterious	3,72	23,3	0,26	0,55	neutral	0,36	disease	0,86	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	3,35	0,49	0,9	2,34	6,69	P	0,64	P	0,85	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6796	6796	A	T	MI.3788	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	893	298	D	V	gAc/gTc	6,38	1	0	probably_damaging	1	deleterious	0	neutral	2,68	deleterious	-4,93	deleterious	-5,83	medium_impact	3,32	damaging	0,59	damaging	0,05	deleterious	3,81	23,4	0,24	0,55	neutral	0,25	disease	0,94	disease	0,63	disease	0,77	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	medium_impact	1,97	0,4	0,9	2,34	6,69	N	0,38	N	0,93	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6797	6797	C	A	MI.3789	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	894	298	D	E	gaC/gaA	5,68	1	0	probably_damaging	0,94	deleterious	0	neutral	2,75	neutral	-2,19	deleterious	-2,52	high_impact	3,56	damaging	0,55	damaging	0,06	deleterious	4,3	24	0,46	0,55	neutral	0,29	disease	0,83	neutral	0,44	disease	0,64	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,77	low_impact	-1,88	low_impact	-1,48	high_impact	2,19	0,69	0,9	2,34	6,69	N	0,45	N	0,65	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8704	8704	A	T	MI.379	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	178	60	M	L	Ata/Tta	-9,59	0	0	benign	0	neutral	0,89	neutral	4,47	neutral	1,44	neutral	-0,56	neutral_impact	-0,76	neutral	0,95	neutral	0,85	deleterious	0,38	6,44	0,73	0,75	NA	NA	neutral	0,23	neutral	0,4	neutral	0,14	7	neutral	0,11	deleterious	0,95	neutral	-6	neutral	0,14	high_impact	2,09	medium_impact	0,8	low_impact	-1,75	0,6	0,9	26,99	19,59	N	0,33	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6797	6797	C	G	MI.3790	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	894	298	D	E	gaC/gaG	5,68	1	0	probably_damaging	0,94	deleterious	0	neutral	2,75	neutral	-2,19	deleterious	-2,52	high_impact	3,56	damaging	0,55	damaging	0,06	deleterious	3,94	23,5	0,46	0,55	neutral	0,29	disease	0,83	neutral	0,44	disease	0,64	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,77	low_impact	-1,88	low_impact	-1,48	high_impact	2,19	0,69	0,9	2,34	6,69	N	0,44	N	0,65	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6798	6798	G	T	MI.3791	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	895	299	V	L	Gta/Tta	-1,72	0	0	probably_damaging	0,97	neutral	0,13	neutral	2,87	neutral	-0,52	neutral	-1,81	medium_impact	2,58	damaging	0,57	damaging	0,06	deleterious	1,83	15,15	0,41	0,55	neutral	0,41	disease	0,73	neutral	0,36	neutral	0,43	1	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,74	low_impact	-2,18	medium_impact	-0,27	medium_impact	1,28	0,89	0,9	4,29	7,92	N	0,29	N	0,55	disease_causing	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6798	6798	G	C	MI.3792	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	895	299	V	L	Gta/Cta	-1,72	0	0	probably_damaging	0,97	neutral	0,13	neutral	2,87	neutral	-0,52	neutral	-1,81	medium_impact	2,58	damaging	0,57	damaging	0,06	neutral	1,73	14,58	0,41	0,55	neutral	0,41	disease	0,73	neutral	0,36	neutral	0,43	1	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,74	low_impact	-2,18	medium_impact	-0,27	medium_impact	1,28	0,89	0,9	4,29	7,92	N	0,29	N	0,55	disease_causing	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6798	6798	G	A	MI.3793	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	895	299	V	M	Gta/Ata	-1,72	0	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-2,67	neutral	-1,89	high_impact	3,96	damaging	0,57	damaging	0,07	deleterious	3,71	23,3	0,4	0,55	disease	0,67	disease	0,77	neutral	0,39	disease	0,56	1	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,56	0,78	0,9	4,29	7,92	N	0,31	N	0,82	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6799	6799	T	C	MI.3794	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	896	299	V	A	gTa/gCa	5,22	1	0	probably_damaging	1	deleterious	0,03	neutral	2,86	neutral	-0,57	deleterious	-2,55	medium_impact	2,83	damaging	0,58	damaging	0,1	deleterious	3,35	22,9	0,34	0,55	neutral	0,32	disease	0,64	neutral	0,3	neutral	0,39	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,72	low_impact	-3,58	medium_impact	-0,65	medium_impact	1,51	0,43	0,9	4,29	7,92	N	0,45	N	0,47	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6799	6799	T	A	MI.3795	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	896	299	V	E	gTa/gAa	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,82	neutral	-1,4	deleterious	-3,91	high_impact	4,58	damaging	0,56	damaging	0,08	deleterious	4,69	24,6	0,11	0,55	neutral	0,27	disease	0,89	disease	0,65	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,13	0,46	0,9	4,29	7,92	P	0,52	P	0,84	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6799	6799	T	G	MI.3796	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	896	299	V	G	gTa/gGa	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,81	neutral	-2,38	deleterious	-4,55	high_impact	4,04	damaging	0,57	damaging	0,08	deleterious	3,87	23,5	0,15	0,55	neutral	0,43	disease	0,87	disease	0,56	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,63	0,54	0,9	4,29	7,92	N	0,43	N	0,71	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6801	6801	G	C	MI.3797	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	898	300	D	H	Gac/Cac	-8,89	0	0	probably_damaging	1	deleterious	0	neutral	2,83	deleterious	-3,02	deleterious	-4,56	high_impact	4,84	damaging	0,58	damaging	0,04	deleterious	3,72	23,3	0,35	0,55	disease	0,61	disease	0,88	disease	0,69	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,56	0,9	1,36	6,75	P	0,63	P	0,97	polymorphism	0,74	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6801	6801	G	T	MI.3798	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	898	300	D	Y	Gac/Tac	-8,89	0	0	probably_damaging	1	deleterious	0	neutral	2,9	neutral	-1,06	deleterious	-5,88	high_impact	4,49	damaging	0,53	damaging	0,05	deleterious	4,01	23,6	0,29	0,55	disease	0,57	disease	0,94	disease	0,64	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,05	0,3	0,9	1,36	6,75	N	0,38	N	0,94	polymorphism	0,57	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6801	6801	G	A	MI.3799	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	898	300	D	N	Gac/Aac	-8,89	0	0	probably_damaging	0,99	deleterious	0,02	neutral	2,85	neutral	-2,19	deleterious	-3,22	high_impact	3,8	damaging	0,48	damaging	0,05	deleterious	4,3	24	0,56	0,6	neutral	0,34	disease	0,83	disease	0,55	neutral	0,49	0	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-2,64	medium_impact	-0,75	high_impact	2,41	0,77	0,9	1,36	6,75	N	0,31	N	0,89	polymorphism	0,94	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8543	8543	T	C	MI.38	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	17	6	F	S	tTc/tCc	4,76	1	0	probably_damaging	0,97	deleterious	0,01	neutral	3,9	neutral	-1,89	deleterious	-6,56	medium_impact	3,32	neutral	0,77	neutral	0,66	deleterious	4,15	23,8	0,44	0,65	disease	0,64	disease	0,74	disease	0,78	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-2,19	medium_impact	-0,84	medium_impact	1,75	0,24	0,9	39,82	8,43	P	0,56	P	0,99	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8704	8704	A	C	MI.380	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	178	60	M	L	Ata/Cta	-9,59	0	0	benign	0	neutral	0,89	neutral	4,47	neutral	1,44	neutral	-0,56	neutral_impact	-0,76	neutral	0,95	neutral	0,85	deleterious	0,2	4,63	0,73	0,75	NA	NA	neutral	0,23	neutral	0,4	neutral	0,14	7	neutral	0,11	deleterious	0,95	neutral	-6	neutral	0,14	high_impact	2,09	medium_impact	0,8	low_impact	-1,75	0,6	0,9	26,99	19,59	N	0,33	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6802	6802	A	G	MI.3800	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	899	300	D	G	gAc/gGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,85	neutral	-2,01	deleterious	-4,57	high_impact	4,49	damaging	0,58	damaging	0,06	deleterious	4,05	23,7	0,26	0,55	disease	0,55	disease	0,91	disease	0,67	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,05	0,47	0,9	1,36	6,75	P	0,5	N	0,85	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6802	6802	A	T	MI.3801	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	899	300	D	V	gAc/gTc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,9	neutral	-1,02	deleterious	-5,89	high_impact	3,83	damaging	0,55	damaging	0,05	deleterious	3,82	23,4	0,25	0,55	neutral	0,17	disease	0,94	disease	0,65	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,44	0,28	0,9	1,36	6,75	N	0,45	N	0,93	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6802	6802	A	C	MI.3802	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	899	300	D	A	gAc/gCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,91	neutral	-0,86	deleterious	-5,23	high_impact	4,63	neutral	0,63	damaging	0,09	deleterious	3,77	23,4	0,3	0,55	neutral	0,25	disease	0,85	disease	0,65	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,18	0,37	0,9	1,36	6,75	P	0,5	N	0,85	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6803	6803	C	A	MI.3803	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	900	300	D	E	gaC/gaA	8,69	1	0	probably_damaging	0,97	deleterious	0	neutral	2,84	neutral	-2,3	deleterious	-2,61	high_impact	4,63	damaging	0,51	damaging	0,06	deleterious	4,24	23,9	0,44	0,55	neutral	0,4	disease	0,82	disease	0,52	disease	0,62	2	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,79	low_impact	-2,18	low_impact	-1,48	high_impact	3,18	0,62	0,9	1,36	6,75	P	0,49	N	0,65	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6803	6803	C	G	MI.3804	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	900	300	D	E	gaC/gaG	8,69	1	0	probably_damaging	0,97	deleterious	0	neutral	2,84	neutral	-2,3	deleterious	-2,61	high_impact	4,63	damaging	0,51	damaging	0,06	deleterious	3,92	23,5	0,44	0,55	neutral	0,4	disease	0,82	disease	0,52	disease	0,62	2	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,79	low_impact	-2,18	low_impact	-1,48	high_impact	3,18	0,62	0,9	1,36	6,75	P	0,49	N	0,65	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6804	6804	A	C	MI.3805	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	901	301	T	P	Aca/Cca	-5,42	0	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-2,7	deleterious	-3,9	medium_impact	3,26	damaging	0,59	neutral	0,44	deleterious	3,57	23,2	0,14	0,55	disease	0,72	disease	0,83	disease	0,71	disease	0,73	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	medium_impact	1,91	0,54	0,9	3,51	6,73	N	0,29	N	0,92	disease_causing	0,99	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6804	6804	A	G	MI.3806	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	901	301	T	A	Aca/Gca	-5,42	0	0	probably_damaging	0,97	deleterious	0	neutral	2,78	neutral	-0,37	deleterious	-3,21	high_impact	3,91	neutral	0,75	neutral	0,57	deleterious	3,48	23,1	0,6	0,65	neutral	0,21	disease	0,67	neutral	0,48	neutral	0,45	1	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,68	low_impact	-2,18	low_impact	-1,48	high_impact	2,51	0,51	0,9	3,51	6,73	N	0,45	N	0,69	disease_causing	0,95	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6804	6804	A	T	MI.3807	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	901	301	T	S	Aca/Tca	-5,42	0	0	probably_damaging	0,97	neutral	0,19	neutral	2,76	neutral	-0,63	deleterious	-2,52	medium_impact	2,25	damaging	0,58	neutral	0,73	deleterious	3,27	22,8	0,44	0,55	neutral	0,32	disease	0,7	neutral	0,29	neutral	0,45	1	deleterious	0,98	neutral	0,11	deleterious	1	deleterious	0,73	low_impact	-2,18	medium_impact	-0,16	medium_impact	0,98	0,72	0,9	3,51	6,73	N	0,42	N	0,79	disease_causing	0,87	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6805	6805	C	T	MI.3808	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	902	301	T	M	aCa/aTa	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-1,36	deleterious	-3,89	high_impact	4,13	neutral	0,61	neutral	0,58	deleterious	4,16	23,8	0,34	0,55	disease	0,57	disease	0,83	neutral	0,49	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,61	0,9	3,51	6,73	P	0,49	N	0,96	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6805	6805	C	A	MI.3809	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	902	301	T	K	aCa/aAa	6,84	1	0	probably_damaging	0,99	deleterious	0	neutral	2,69	neutral	-2,54	deleterious	-3,88	high_impact	4,76	neutral	0,63	neutral	0,42	deleterious	4,54	24,3	0,23	0,55	neutral	0,46	disease	0,89	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	3,3	0,56	0,9	3,51	6,73	P	0,71	P	0,88	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8705	8705	T	C	MI.381	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	179	60	M	T	aTa/aCa	4,99	0,98	0,01	benign	0	neutral	0,49	neutral	4,47	neutral	1,51	neutral	0,32	neutral_impact	-0,69	neutral	0,98	neutral	0,98	neutral	-0,64	0,1	0,61	0,7	NA	NA	neutral	0,38	neutral	0,45	neutral	0,14	7	neutral	0,51	deleterious	0,75	neutral	-6	neutral	0,11	high_impact	2,09	medium_impact	0,28	low_impact	-1,69	0,13	0,9	26,99	19,59	P	0,53	P	0,04	polymorphism	1	0,01	rs878959404	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6807	6807	C	G	MI.3810	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	904	302	R	G	Cga/Gga	-8,43	0	0	benign	0,02	deleterious	0	neutral	2,79	neutral	-0,59	deleterious	-4,61	high_impact	4,38	damaging	0,57	damaging	0,04	deleterious	2,42	18,92	0,24	0,55	disease	0,5	disease	0,85	disease	0,74	disease	0,73	5	deleterious	1	deleterious	0,49	deleterious	2	neutral	0,29	medium_impact	0,83	low_impact	-1,48	high_impact	2,95	0,37	0,9	1,36	7,12	N	0,4	N	0,92	polymorphism	0,88	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6807	6807	C	T	MI.3811	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	904	302	R	W	Cga/Tga	-8,43	0	0	probably_damaging	1	deleterious	0	neutral	2,77	deleterious	-5,11	deleterious	-5,27	high_impact	5,19	damaging	0,5	damaging	0,03	deleterious	5,32	25,8	0,37	0,55	disease	0,52	disease	0,88	disease	0,75	disease	0,74	5	deleterious	1	deleterious	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,72	0,9	1,36	7,12	P	0,59	P	1	polymorphism	0,72	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6808	6808	G	T	MI.3812	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	905	302	R	L	cGa/cTa	5,68	1	0	possibly_damaging	0,88	deleterious	0	neutral	2,94	neutral	-1,42	deleterious	-4,61	high_impact	3,66	neutral	0,61	damaging	0,02	deleterious	4,34	24	0,26	0,55	neutral	0,38	disease	0,9	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,77	low_impact	-1,57	low_impact	-1,48	high_impact	2,28	0,32	0,9	1,36	7,12	P	0,54	P	0,99	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6808	6808	G	C	MI.3813	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	905	302	R	P	cGa/cCa	5,68	1	0	probably_damaging	0,98	deleterious	0	neutral	2,78	neutral	-2,65	deleterious	-4,61	high_impact	4,49	damaging	0,44	damaging	0,03	deleterious	4,34	24	0,18	0,55	disease	0,68	disease	0,87	disease	0,81	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,35	low_impact	-1,48	high_impact	3,05	0,22	0,9	1,36	7,12	P	0,68	P	0,99	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6808	6808	G	A	MI.3814	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	905	302	R	Q	cGa/cAa	5,68	1	0	probably_damaging	0,95	deleterious	0	neutral	2,9	neutral	-0,98	deleterious	-2,63	high_impact	4,09	damaging	0,58	damaging	0,02	deleterious	4,58	24,4	0,46	0,55	neutral	0,4	disease	0,78	disease	0,66	neutral	0,47	1	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,76	low_impact	-1,96	low_impact	-1,48	high_impact	2,68	0,79	0,9	1,36	7,12	P	0,56	P	0,99	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6810	6810	G	C	MI.3815	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	907	303	A	P	Gca/Cca	0,13	0,97	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-3,08	deleterious	-3,3	high_impact	3,7	damaging	0,54	damaging	0,15	deleterious	1,99	16,13	0,11	0,55	neutral	0,49	disease	0,89	disease	0,76	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,32	0,82	0,9	2,34	6,8	N	0,46	N	0,85	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6810	6810	G	T	MI.3816	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	907	303	A	S	Gca/Tca	0,13	0,97	0	probably_damaging	1	neutral	0,06	neutral	2,66	neutral	-1,36	neutral	-1,96	medium_impact	2,62	neutral	0,63	damaging	0,18	deleterious	2,23	17,71	0,36	0,55	neutral	0,31	disease	0,87	disease	0,54	disease	0,51	0	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,83	low_impact	-3,58	medium_impact	-0,47	medium_impact	1,32	0,85	0,9	2,34	6,8	N	0,39	N	0,64	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6810	6810	G	A	MI.3817	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	907	303	A	T	Gca/Aca	0,13	0,97	0	probably_damaging	1	neutral	0,05	neutral	2,72	neutral	-0,67	deleterious	-2,63	high_impact	4,08	damaging	0,56	damaging	0,15	deleterious	3,94	23,5	0,44	0,55	neutral	0,36	disease	0,86	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,84	low_impact	-3,58	medium_impact	-0,52	high_impact	2,67	0,8	0,9	2,34	6,8	N	0,45	N	0,2	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6811	6811	C	T	MI.3818	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	908	303	A	V	gCa/gTa	7,3	1	0	probably_damaging	1	neutral	0,07	neutral	2,66	neutral	-1,25	deleterious	-2,64	high_impact	3,62	damaging	0,42	damaging	0,16	deleterious	4,19	23,8	0,33	0,55	neutral	0,3	disease	0,9	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,82	low_impact	-3,58	medium_impact	-0,43	high_impact	2,24	0,77	0,9	2,34	6,8	P	0,7	P	0,75	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6811	6811	C	A	MI.3819	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	908	303	A	E	gCa/gAa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-3,74	deleterious	-3,29	high_impact	5,12	damaging	0,57	damaging	0,16	deleterious	4,53	24,3	0,13	0,55	neutral	0,5	disease	0,92	disease	0,73	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,63	0,72	0,9	2,34	6,8	P	0,73	P	0,76	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8705	8705	T	A	MI.382	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	179	60	M	K	aTa/aAa	4,99	0,98	0,01	benign	0,04	neutral	0,3	neutral	4,44	neutral	1,11	neutral	-1,14	neutral_impact	0,38	neutral	0,83	neutral	0,44	deleterious	1,93	15,76	0,35	0,65	NA	NA	disease	0,59	disease	0,55	disease	0,61	2	neutral	0,68	deleterious	0,63	neutral	-6	neutral	0,23	medium_impact	0,55	medium_impact	0,08	medium_impact	-0,77	0,51	0,9	26,99	19,59	N	0,5	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6811	6811	C	G	MI.3820	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	908	303	A	G	gCa/gGa	7,3	1	0	probably_damaging	0,99	deleterious	0	neutral	2,58	deleterious	-3,14	deleterious	-2,63	high_impact	4,15	damaging	0,54	damaging	0,17	deleterious	2,29	18,1	0,31	0,55	neutral	0,47	disease	0,87	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,64	low_impact	-1,48	high_impact	2,73	0,84	0,9	2,34	6,8	P	0,5	N	0,56	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6813	6813	T	C	MI.3821	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	910	304	Y	H	Tat/Cat	-7,04	0	0	probably_damaging	1	deleterious	0	neutral	2,7	deleterious	-3,03	deleterious	-3,28	high_impact	4,38	neutral	0,66	damaging	0,09	deleterious	3,7	23,3	0,31	0,55	disease	0,67	disease	0,88	disease	0,79	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,95	0,43	0,9	2,34	6,64	N	0,46	N	0,61	polymorphism	0,92	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6813	6813	T	G	MI.3822	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	910	304	Y	D	Tat/Gat	-7,04	0	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-2,25	deleterious	-6,55	high_impact	5,19	neutral	0,6	damaging	0,09	deleterious	4,1	23,7	0,17	0,55	disease	0,75	disease	0,93	disease	0,8	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,35	0,9	2,34	6,64	P	0,64	P	0,98	polymorphism	0,6	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6813	6813	T	A	MI.3823	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	910	304	Y	N	Tat/Aat	-7,04	0	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-2,76	deleterious	-5,9	high_impact	5,19	damaging	0,58	damaging	0,11	deleterious	4,15	23,8	0,29	0,55	disease	0,63	disease	0,91	disease	0,74	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,28	0,9	2,34	6,64	P	0,63	P	0,94	polymorphism	0,52	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6814	6814	A	C	MI.3824	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	911	304	Y	S	tAt/tCt	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,74	neutral	-1,29	deleterious	-5,89	high_impact	4,09	neutral	0,69	damaging	0,14	deleterious	3,6	23,2	0,25	0,55	neutral	0,38	disease	0,92	disease	0,7	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,68	0,36	0,9	2,34	6,64	N	0,49	N	0,9	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6814	6814	A	T	MI.3825	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	911	304	Y	F	tAt/tTt	5,68	1	0	probably_damaging	0,98	neutral	0,1	neutral	2,94	neutral	1,15	deleterious	-2,62	medium_impact	2,9	damaging	0,54	damaging	0,1	deleterious	3,28	22,8	0,3	0,55	neutral	0,18	disease	0,9	disease	0,64	disease	0,71	4	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,77	low_impact	-2,35	medium_impact	-0,34	medium_impact	1,58	0,49	0,9	2,34	6,64	P	0,49	N	0,5	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6814	6814	A	G	MI.3826	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	911	304	Y	C	tAt/tGt	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-2,86	deleterious	-5,91	high_impact	5,19	damaging	0,51	damaging	0,1	deleterious	3,43	23	0,33	0,55	disease	0,62	disease	0,92	disease	0,75	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,32	0,9	2,34	6,64	P	0,69	P	0,89	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6816	6816	T	G	MI.3827	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	913	305	F	V	Ttc/Gtc	-1,72	0	0	probably_damaging	1	deleterious	0,01	neutral	2,65	neutral	-2,48	deleterious	-4,62	high_impact	5,27	neutral	0,71	damaging	0,07	deleterious	4,28	24	0,21	0,55	disease	0,62	disease	0,91	disease	0,78	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,58	medium_impact	-0,92	high_impact	3,77	0,58	0,9	1,75	6,66	P	0,72	P	0,84	polymorphism	0,53	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6816	6816	T	C	MI.3828	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	913	305	F	L	Ttc/Ctc	-1,72	0	0	probably_damaging	0,99	deleterious	0	neutral	2,67	neutral	-2,48	deleterious	-3,96	high_impact	4,58	neutral	0,84	damaging	0,05	deleterious	4,29	24	0,36	0,55	disease	0,57	disease	0,84	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	3,13	0,73	0,9	1,75	6,66	N	0,39	N	0,83	polymorphism	0,69	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6816	6816	T	A	MI.3829	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	913	305	F	I	Ttc/Atc	-1,72	0	0	probably_damaging	0,99	deleterious	0	neutral	2,65	neutral	-2,58	deleterious	-3,96	high_impact	4,92	neutral	0,73	damaging	0,08	deleterious	4,67	24,5	0,19	0,55	neutral	0,49	disease	0,88	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,64	low_impact	-1,48	high_impact	3,44	0,65	0,9	1,75	6,66	P	0,73	P	0,88	polymorphism	0,71	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8706	8706	A	C	MI.383	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	180	60	M	I	atA/atC	2,21	0,98	0,01	benign	0,01	neutral	0,5	neutral	4,39	neutral	0,01	neutral	-0,38	neutral_impact	-1,04	neutral	0,88	neutral	0,97	neutral	-0,15	1,4	0,77	0,8	NA	NA	neutral	0,32	disease	0,51	neutral	0,23	5	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,17	medium_impact	1,14	medium_impact	0,29	low_impact	-1,99	0,56	0,9	26,99	19,59	N	0,46	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6817	6817	T	A	MI.3830	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	914	305	F	Y	tTc/tAc	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,63	deleterious	-4,3	neutral	-1,98	high_impact	3,92	neutral	0,69	damaging	0,06	deleterious	4,27	23,9	0,21	0,55	neutral	0,49	disease	0,82	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,64	low_impact	-1,48	high_impact	2,52	0,73	0,9	1,75	6,66	P	0,54	P	0,59	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6817	6817	T	C	MI.3831	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	914	305	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-3,48	deleterious	-5,29	high_impact	4,12	neutral	0,73	damaging	0,08	deleterious	4,34	24	0,15	0,55	disease	0,74	disease	0,89	disease	0,75	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,55	0,9	1,75	6,66	P	0,54	P	0,84	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6817	6817	T	G	MI.3832	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	914	305	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-5,32	deleterious	-5,29	high_impact	5,27	neutral	0,69	damaging	0,05	deleterious	4,18	23,8	0,17	0,55	disease	0,89	disease	0,88	disease	0,77	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,77	0,41	0,9	1,75	6,66	P	0,69	P	0,91	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6818	6818	C	G	MI.3833	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	915	305	F	L	ttC/ttG	5,91	1	0	probably_damaging	0,99	deleterious	0	neutral	2,67	neutral	-2,48	deleterious	-3,96	high_impact	4,58	neutral	0,84	damaging	0,05	deleterious	4,42	24,2	0,36	0,55	disease	0,57	disease	0,84	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	3,13	0,73	0,9	1,75	6,66	P	0,54	P	0,83	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6818	6818	C	A	MI.3834	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	915	305	F	L	ttC/ttA	5,91	1	0	probably_damaging	0,99	deleterious	0	neutral	2,67	neutral	-2,48	deleterious	-3,96	high_impact	4,58	neutral	0,84	damaging	0,05	deleterious	4,71	24,6	0,36	0,55	disease	0,57	disease	0,84	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	3,13	0,73	0,9	1,75	6,66	P	0,54	P	0,83	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6819	6819	A	T	MI.3835	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	916	306	T	S	Acc/Tcc	-3,57	0	0	probably_damaging	0,98	neutral	0,18	neutral	2,86	neutral	0,36	deleterious	-2,52	medium_impact	2,17	neutral	0,64	damaging	0,08	deleterious	3,33	22,9	0,41	0,55	neutral	0,17	disease	0,71	neutral	0,39	neutral	0,35	3	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,71	low_impact	-2,35	medium_impact	-0,17	medium_impact	0,91	0,78	0,9	2,73	6,69	N	0,27	N	0,79	disease_causing	0,92	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6819	6819	A	C	MI.3836	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	916	306	T	P	Acc/Ccc	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-3,86	deleterious	-3,9	high_impact	5,11	damaging	0,5	damaging	0,08	deleterious	3,57	23,1	0,15	0,55	disease	0,66	disease	0,85	disease	0,77	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,62	0,9	2,73	6,69	P	0,69	P	0,92	disease_causing	0,99	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6819	6819	A	G	MI.3837	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	916	306	T	A	Acc/Gcc	-3,57	0	0	probably_damaging	0,98	deleterious	0	neutral	2,7	neutral	-1,06	deleterious	-3,22	high_impact	3,61	neutral	0,69	damaging	0,06	deleterious	3,57	23,2	0,42	0,55	neutral	0,34	disease	0,67	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,71	low_impact	-2,35	low_impact	-1,48	high_impact	2,23	0,63	0,9	2,73	6,69	N	0,31	N	0,69	disease_causing	0,97	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6820	6820	C	T	MI.3838	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	917	306	T	I	aCc/aTc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-0,79	deleterious	-3,91	high_impact	4,3	neutral	0,64	damaging	0,04	deleterious	4,1	23,7	0,28	0,55	neutral	0,41	disease	0,9	disease	0,65	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,87	0,76	0,9	2,73	6,69	P	0,48	N	0,92	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6820	6820	C	G	MI.3839	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	917	306	T	S	aCc/aGc	7,07	1	0	probably_damaging	0,98	neutral	0,18	neutral	2,86	neutral	0,36	deleterious	-2,52	medium_impact	2,17	neutral	0,64	damaging	0,08	deleterious	3,57	23,2	0,41	0,55	neutral	0,17	disease	0,71	neutral	0,39	neutral	0,35	3	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,71	low_impact	-2,35	medium_impact	-0,17	medium_impact	0,91	0,78	0,9	2,73	6,69	N	0,47	N	0,79	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8706	8706	A	T	MI.384	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	180	60	M	I	atA/atT	2,21	0,98	0,01	benign	0,01	neutral	0,5	neutral	4,39	neutral	0,01	neutral	-0,38	neutral_impact	-1,04	neutral	0,88	neutral	0,97	neutral	-0,11	1,68	0,77	0,8	NA	NA	neutral	0,32	disease	0,51	neutral	0,23	5	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,17	medium_impact	1,14	medium_impact	0,29	low_impact	-1,99	0,56	0,9	26,99	19,59	N	0,46	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6820	6820	C	A	MI.3840	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	917	306	T	N	aCc/aAc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,63	neutral	-2,39	deleterious	-3,22	high_impact	5,11	damaging	0,58	damaging	0,05	deleterious	3,8	23,4	0,32	0,55	disease	0,54	disease	0,85	disease	0,66	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,77	0,9	2,73	6,69	P	0,7	P	0,8	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6822	6822	T	A	MI.3841	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	919	307	S	T	Tcc/Acc	-3,57	0	0	probably_damaging	0,95	deleterious	0,02	neutral	2,81	neutral	-0,01	neutral	-1,25	medium_impact	2,62	damaging	0,5	damaging	0,08	deleterious	3,85	23,4	0,28	0,55	neutral	0,25	disease	0,57	neutral	0,38	neutral	0,41	2	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,68	low_impact	-1,96	medium_impact	-0,75	medium_impact	1,32	0,89	0,9	2,53	6,65	N	0,34	N	0,43	disease_causing	0,99	0,03	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	6822	6822	T	C	MI.3842	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	919	307	S	P	Tcc/Ccc	-3,57	0	0	probably_damaging	0,99	deleterious	0	neutral	2,71	neutral	-2,1	neutral	-2,26	high_impact	4,62	damaging	0,44	damaging	0,05	deleterious	4,08	23,7	0,18	0,55	disease	0,64	disease	0,86	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,64	low_impact	-1,48	high_impact	3,17	0,78	0,9	2,53	6,65	P	0,51	P	0,91	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6822	6822	T	G	MI.3843	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	919	307	S	A	Tcc/Gcc	-3,57	0	0	probably_damaging	0,97	neutral	0,63	neutral	2,86	neutral	0,5	neutral	0,01	neutral_impact	0,29	damaging	0,53	damaging	0,19	deleterious	1,84	15,25	0,45	0,55	neutral	0,17	neutral	0,09	neutral	0,28	neutral	0,21	6	neutral	0,97	neutral	0,33	neutral	-2	deleterious	0,6	low_impact	-2,18	medium_impact	0,32	medium_impact	-0,83	0,74	0,9	2,53	6,65	N	0,33	N	0,35	disease_causing	0,95	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6823	6823	C	T	MI.3844	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	920	307	S	F	tCc/tTc	4,76	1	0	probably_damaging	1	deleterious	0	neutral	2,81	neutral	-0,03	deleterious	-2,92	medium_impact	2,86	damaging	0,49	damaging	0,04	deleterious	4,35	24,1	0,2	0,55	neutral	0,31	disease	0,84	disease	0,56	neutral	0,46	1	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	medium_impact	1,54	0,55	0,9	2,53	6,65	N	0,4	N	0,98	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6823	6823	C	G	MI.3845	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	920	307	S	C	tCc/tGc	4,76	1	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-2,94	neutral	-1,96	high_impact	4,27	damaging	0,48	damaging	0,02	deleterious	3,68	23,3	0,27	0,55	disease	0,62	disease	0,79	disease	0,58	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,84	0,78	0,9	2,53	6,65	N	0,46	N	0,85	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6823	6823	C	A	MI.3846	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	920	307	S	Y	tCc/tAc	4,76	1	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-1,95	deleterious	-2,92	high_impact	3,92	damaging	0,47	damaging	0,04	deleterious	4,14	23,8	0,22	0,55	neutral	0,39	disease	0,82	disease	0,63	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,52	0,75	0,9	2,53	6,65	N	0,46	N	0,92	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6825	6825	G	C	MI.3847	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	922	308	A	P	Gct/Cct	-11,21	0	0	possibly_damaging	0,9	deleterious	0	neutral	2,76	deleterious	-3,48	deleterious	-3,3	high_impact	5,11	damaging	0,52	neutral	0,47	deleterious	3,98	23,6	0,14	0,55	neutral	0,3	disease	0,89	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,8	low_impact	-1,65	low_impact	-1,48	high_impact	3,62	0,79	0,9	2,34	7,25	P	0,65	P	0,85	polymorphism	0,72	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6825	6825	G	A	MI.3848	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	922	308	A	T	Gct/Act	-11,21	0	0	benign	0,06	deleterious	0	neutral	2,83	neutral	-1,56	deleterious	-2,63	medium_impact	3,08	damaging	0,56	neutral	0,44	deleterious	4,32	24	0,44	0,55	neutral	0,28	disease	0,84	disease	0,54	disease	0,58	2	deleterious	1	deleterious	0,47	deleterious	1	neutral	0,27	medium_impact	0,37	low_impact	-1,48	medium_impact	1,75	0,75	0,9	2,34	7,25	N	0,4	N	0,2	polymorphism	0,9	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6825	6825	G	T	MI.3849	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	922	308	A	S	Gct/Tct	-11,21	0	0	possibly_damaging	0,63	deleterious	0	neutral	2,8	neutral	-2,13	neutral	-1,98	high_impact	3,9	neutral	0,67	neutral	0,56	deleterious	3,79	23,4	0,35	0,55	neutral	0,34	disease	0,87	disease	0,52	disease	0,68	4	deleterious	1	neutral	0,19	deleterious	5	deleterious	0,46	medium_impact	-0,97	low_impact	-1,48	high_impact	2,5	0,81	0,9	2,34	7,25	N	0,47	N	0,64	polymorphism	0,95	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8707	8707	C	A	MI.385	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	181	61	H	N	Cac/Aac	-12,83	0	0	probably_damaging	0,98	neutral	0,07	neutral	4,38	neutral	-0,55	deleterious	-3,82	neutral_impact	0,44	neutral	0,89	damaging	0,1	deleterious	3,76	23,3	0,58	0,7	neutral	0,38	neutral	0,44	disease	0,68	neutral	0,49	0	deleterious	0,99	neutral	0,05	neutral	-2	deleterious	0,7	low_impact	-2,36	medium_impact	-0,34	medium_impact	-0,72	0,49	0,9	48,67	8,33	N	0,38	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6826	6826	C	T	MI.3850	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	923	308	A	V	gCt/gTt	9,15	1	0	possibly_damaging	0,5	neutral	0,11	neutral	2,87	neutral	-1,07	deleterious	-2,63	medium_impact	2,4	damaging	0,4	neutral	0,48	deleterious	4,47	24,2	0,4	0,55	neutral	0,36	disease	0,87	neutral	0,45	neutral	0,38	2	neutral	0,88	neutral	0,31	NA	0	deleterious	0,64	medium_impact	-0,76	medium_impact	-0,31	medium_impact	1,12	0,79	0,9	2,34	7,25	P	0,77	P	0,75	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6826	6826	C	A	MI.3851	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	923	308	A	D	gCt/gAt	9,15	1	0	possibly_damaging	0,87	deleterious	0	neutral	2,76	deleterious	-3,7	deleterious	-3,95	high_impact	5,11	damaging	0,6	neutral	0,44	deleterious	4,53	24,3	0,14	0,55	disease	0,68	disease	0,93	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,83	low_impact	-1,53	low_impact	-1,48	high_impact	3,62	0,74	0,9	2,34	7,25	P	0,72	P	0,89	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6826	6826	C	G	MI.3852	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	923	308	A	G	gCt/gGt	9,15	1	0	benign	0,38	deleterious	0	neutral	2,77	deleterious	-3,28	deleterious	-2,64	high_impact	4,55	damaging	0,57	neutral	0,57	deleterious	4,06	23,7	0,31	0,55	disease	0,64	disease	0,85	disease	0,62	disease	0,68	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,45	medium_impact	-0,56	low_impact	-1,48	high_impact	3,1	0,82	0,9	2,34	7,25	P	0,54	P	0,56	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6828	6828	A	C	MI.3853	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	925	309	T	P	Acc/Ccc	-8,89	0	0	probably_damaging	1	deleterious	0	neutral	2,12	deleterious	-6,46	deleterious	-3,94	high_impact	4,91	neutral	0,62	damaging	0,09	deleterious	4,04	23,7	0,2	0,55	disease	0,88	disease	0,83	disease	0,75	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,52	0,9	2,14	6,7	P	0,64	P	0,92	polymorphism	0,73	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6828	6828	A	T	MI.3854	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	925	309	T	S	Acc/Tcc	-8,89	0	0	probably_damaging	0,99	deleterious	0,03	neutral	2,64	neutral	-0,93	deleterious	-2,63	medium_impact	3,39	neutral	0,74	damaging	0,08	deleterious	3,92	23,5	0,37	0,55	neutral	0,46	disease	0,75	disease	0,65	disease	0,6	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,78	low_impact	-2,64	medium_impact	-0,65	high_impact	2,03	0,57	0,9	2,14	6,7	N	0,28	N	0,79	polymorphism	0,98	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6828	6828	A	G	MI.3855	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	925	309	T	A	Acc/Gcc	-8,89	0	0	probably_damaging	0,99	deleterious	0	neutral	2,15	deleterious	-4,64	deleterious	-3,29	high_impact	5,25	neutral	0,75	damaging	0,07	deleterious	4,07	23,7	0,47	0,55	disease	0,66	disease	0,64	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-2,64	low_impact	-1,48	high_impact	3,75	0,43	0,9	2,14	6,7	P	0,62	P	0,69	polymorphism	0,93	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6829	6829	C	T	MI.3856	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	926	309	T	I	aCc/aTc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,11	deleterious	-6,97	deleterious	-3,95	high_impact	4,91	neutral	0,71	damaging	0,06	deleterious	4,04	23,7	0,32	0,55	disease	0,89	disease	0,88	disease	0,73	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,63	0,9	2,14	6,7	P	0,71	P	0,92	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6829	6829	C	G	MI.3857	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	926	309	T	S	aCc/aGc	7,07	1	0	probably_damaging	0,99	deleterious	0,03	neutral	2,64	neutral	-0,93	deleterious	-2,63	medium_impact	3,39	neutral	0,74	damaging	0,08	deleterious	3,59	23,2	0,37	0,55	neutral	0,46	disease	0,75	disease	0,65	disease	0,6	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,78	low_impact	-2,64	medium_impact	-0,65	high_impact	2,03	0,57	0,9	2,14	6,7	N	0,49	N	0,79	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6829	6829	C	A	MI.3858	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	926	309	T	N	aCc/aAc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,13	deleterious	-5,46	deleterious	-3,29	high_impact	4,91	neutral	0,69	damaging	0,06	deleterious	3,71	23,3	0,43	0,55	disease	0,83	disease	0,85	disease	0,76	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,8	0,9	2,14	6,7	P	0,71	P	0,8	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6831	6831	A	G	MI.3859	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	928	310	M	V	Ata/Gta	-10,28	0	0	probably_damaging	0,94	deleterious	0	neutral	2,69	neutral	-1,42	deleterious	-2,63	high_impact	4,28	damaging	0,59	damaging	0,1	deleterious	2,95	22,1	0,43	0,55	neutral	0,43	disease	0,85	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,78	low_impact	-1,88	low_impact	-1,48	high_impact	2,85	0,36	0,9	2,34	6,69	N	0,36	N	0,88	polymorphism	0,99	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8707	8707	C	T	MI.386	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	181	61	H	Y	Cac/Tac	-12,83	0	0	probably_damaging	0,98	neutral	0,26	neutral	4,41	neutral	0,74	deleterious	-2,57	neutral_impact	0,39	neutral	0,96	damaging	0,12	deleterious	3,57	23,1	0,62	0,7	neutral	0,45	neutral	0,45	disease	0,69	disease	0,5	0	deleterious	0,98	neutral	0,14	neutral	-2	deleterious	0,68	low_impact	-2,36	medium_impact	0,04	medium_impact	-0,76	0,23	0,9	48,67	8,33	N	0,33	N	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6831	6831	A	C	MI.3860	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	928	310	M	L	Ata/Cta	-10,28	0	0	possibly_damaging	0,9	deleterious	0,04	neutral	2,71	neutral	0,1	neutral	-1,97	medium_impact	3,42	neutral	0,64	damaging	0,1	deleterious	3,44	23	0,41	0,55	neutral	0,25	disease	0,78	disease	0,53	neutral	0,24	5	deleterious	0,99	neutral	0,07	deleterious	4	deleterious	0,67	low_impact	-1,65	medium_impact	-0,58	high_impact	2,06	0,41	0,9	2,34	6,69	N	0,33	N	0,61	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6831	6831	A	T	MI.3861	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	928	310	M	L	Ata/Tta	-10,28	0	0	possibly_damaging	0,9	deleterious	0,04	neutral	2,71	neutral	0,1	neutral	-1,97	medium_impact	3,42	neutral	0,64	damaging	0,1	deleterious	3,63	23,2	0,41	0,55	neutral	0,25	disease	0,78	disease	0,53	neutral	0,24	5	deleterious	0,99	neutral	0,07	deleterious	4	deleterious	0,67	low_impact	-1,65	medium_impact	-0,58	high_impact	2,06	0,41	0,9	2,34	6,69	N	0,33	N	0,61	polymorphism	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6832	6832	T	C	MI.3862	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	929	310	M	T	aTa/aCa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,59	neutral	-2,42	deleterious	-3,94	high_impact	4,62	neutral	0,63	damaging	0,11	deleterious	3,09	22,5	0,33	0,55	disease	0,61	disease	0,86	disease	0,7	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,17	0,26	0,9	2,34	6,69	P	0,54	P	0,79	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6832	6832	T	A	MI.3863	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	929	310	M	K	aTa/aAa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-3,81	deleterious	-3,94	high_impact	5,17	damaging	0,57	damaging	0,06	deleterious	4,09	23,7	0,19	0,55	disease	0,77	disease	0,91	disease	0,77	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,35	0,9	2,34	6,69	P	0,75	P	0,93	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6833	6833	A	C	MI.3864	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	930	310	M	I	atA/atC	5,91	1	0	probably_damaging	0,96	deleterious	0,01	neutral	2,64	neutral	-1,37	deleterious	-2,62	medium_impact	3,43	damaging	0,52	damaging	0,1	deleterious	3,52	23,1	0,43	0,55	neutral	0,32	disease	0,82	disease	0,65	disease	0,57	1	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,78	low_impact	-2,06	medium_impact	-0,92	high_impact	2,07	0,43	0,9	2,34	6,69	N	0,47	N	0,87	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6833	6833	A	T	MI.3865	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	930	310	M	I	atA/atT	5,91	1	0	probably_damaging	0,96	deleterious	0,01	neutral	2,64	neutral	-1,37	deleterious	-2,62	medium_impact	3,43	damaging	0,52	damaging	0,1	deleterious	3,58	23,2	0,43	0,55	neutral	0,32	disease	0,82	disease	0,65	disease	0,57	1	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,78	low_impact	-2,06	medium_impact	-0,92	high_impact	2,07	0,43	0,9	2,34	6,69	P	0,5	N	0,87	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6834	6834	A	T	MI.3866	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	931	311	I	F	Atc/Ttc	4,06	1	0	probably_damaging	0,99	deleterious	0	neutral	2,69	neutral	-1,97	deleterious	-2,57	high_impact	4,07	damaging	0,6	damaging	0,1	deleterious	3,85	23,4	0,37	0,55	disease	0,51	disease	0,89	disease	0,52	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	2,66	0,73	0,9	1,36	6,72	N	0,47	N	0,85	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6834	6834	A	G	MI.3867	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	931	311	I	V	Atc/Gtc	4,06	1	0	possibly_damaging	0,84	neutral	0,24	neutral	2,8	neutral	-0,76	neutral	-0,48	low_impact	1,5	damaging	0,56	damaging	0,26	deleterious	1,93	15,76	0,56	0,6	neutral	0,28	neutral	0,33	neutral	0,34	neutral	0,38	2	neutral	0,89	neutral	0,2	neutral	-3	deleterious	0,54	low_impact	-1,43	medium_impact	-0,09	medium_impact	0,29	0,59	0,9	1,36	6,72	P	0,59	P	0,23	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6834	6834	A	C	MI.3868	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	931	311	I	L	Atc/Ctc	4,06	1	0	probably_damaging	0,94	neutral	0,05	neutral	3,01	neutral	-0,16	neutral	-1,27	medium_impact	2,34	neutral	0,63	damaging	0,13	deleterious	3,87	23,5	0,38	0,55	neutral	0,18	disease	0,76	neutral	0,46	disease	0,51	0	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,57	low_impact	-1,88	medium_impact	-0,52	medium_impact	1,06	0,69	0,9	1,36	6,72	N	0,49	N	0,61	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6835	6835	T	A	MI.3869	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	932	311	I	N	aTc/aAc	7,07	1	0	probably_damaging	1	deleterious	0,01	neutral	2,66	deleterious	-4,13	deleterious	-4,38	high_impact	4,42	neutral	0,61	damaging	0,12	deleterious	4,67	24,5	0,32	0,55	disease	0,68	disease	0,9	disease	0,61	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,58	medium_impact	-0,92	high_impact	2,98	0,67	0,9	1,36	6,72	P	0,48	N	0,94	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8707	8707	C	G	MI.387	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	181	61	H	D	Cac/Gac	-12,83	0	0	probably_damaging	0,99	neutral	0,06	neutral	4,37	neutral	-1,39	deleterious	-5,17	low_impact	1,59	neutral	0,88	damaging	0,09	deleterious	3,76	23,3	0,38	0,65	neutral	0,5	disease	0,6	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,75	low_impact	-2,65	medium_impact	-0,38	medium_impact	0,27	0,58	0,9	48,67	8,33	N	0,33	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6835	6835	T	G	MI.3870	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	932	311	I	S	aTc/aGc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,68	neutral	-2,51	deleterious	-3,72	high_impact	4,27	neutral	0,69	damaging	0,18	deleterious	4,38	24,1	0,27	0,55	disease	0,51	disease	0,92	disease	0,61	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,84	0,59	0,9	1,36	6,72	N	0,48	N	0,62	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6835	6835	T	C	MI.3871	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	932	311	I	T	aTc/aCc	7,07	1	0	probably_damaging	1	deleterious	0,01	neutral	2,73	neutral	-2,22	deleterious	-2,95	high_impact	3,87	neutral	0,64	damaging	0,14	deleterious	3,55	23,1	0,5	0,6	neutral	0,35	disease	0,81	disease	0,52	disease	0,59	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-3,58	medium_impact	-0,92	high_impact	2,47	0,55	0,9	1,36	6,72	N	0,43	N	0,76	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6836	6836	C	G	MI.3872	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	933	311	I	M	atC/atG	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-1,81	neutral	-1,84	high_impact	3,61	neutral	0,65	damaging	0,15	deleterious	3,46	23	0,54	0,6	neutral	0,39	disease	0,77	neutral	0,5	disease	0,57	1	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	high_impact	2,23	0,76	0,9	1,36	6,72	N	0,43	N	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6836	6836	C	A	MI.3873	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	933	311	I	M	atC/atA	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-1,81	neutral	-1,84	high_impact	3,61	neutral	0,65	damaging	0,15	deleterious	3,96	23,6	0,54	0,6	neutral	0,39	disease	0,77	neutral	0,5	disease	0,57	1	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	high_impact	2,23	0,76	0,9	1,36	6,72	N	0,44	N	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6837	6837	A	C	MI.3874	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	934	312	I	L	Atc/Ctc	-1,03	0,02	0	probably_damaging	0,98	deleterious	0	neutral	2,57	neutral	-2,41	neutral	-1,31	high_impact	4,92	neutral	0,64	damaging	0,09	deleterious	3,92	23,5	0,31	0,55	disease	0,62	disease	0,77	disease	0,57	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,54	low_impact	-2,35	low_impact	-1,48	high_impact	3,44	0,68	0,9	3,9	6,77	P	0,64	P	0,61	disease_causing	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6837	6837	A	T	MI.3875	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	934	312	I	F	Atc/Ttc	-1,03	0,02	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-4,74	deleterious	-2,62	high_impact	4,92	damaging	0,58	damaging	0,08	deleterious	3,84	23,4	0,23	0,55	disease	0,86	disease	0,9	disease	0,63	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,71	0,9	3,9	6,77	P	0,64	P	0,85	disease_causing	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6837	6837	A	G	MI.3876	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	934	312	I	V	Atc/Gtc	-1,03	0,02	0	probably_damaging	0,95	deleterious	0	neutral	2,61	neutral	-1,22	neutral	-0,66	high_impact	3,86	neutral	0,61	damaging	0,12	deleterious	3,16	22,6	0,42	0,55	neutral	0,28	disease	0,66	disease	0,58	disease	0,64	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,55	low_impact	-1,96	low_impact	-1,48	high_impact	2,47	0,68	0,9	3,9	6,77	N	0,41	N	0,23	disease_causing	0,95	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6838	6838	T	G	MI.3877	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	935	312	I	S	aTc/aGc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,45	deleterious	-5,5	deleterious	-3,93	high_impact	5,28	neutral	0,61	damaging	0,13	deleterious	4,41	24,1	0,17	0,55	disease	0,88	disease	0,92	disease	0,68	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,46	0,9	3,9	6,77	P	0,7	P	0,62	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6838	6838	T	C	MI.3878	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	935	312	I	T	aTc/aCc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,45	deleterious	-4,51	deleterious	-3,27	high_impact	4,58	neutral	0,6	damaging	0,09	deleterious	3,54	23,1	0,29	0,55	disease	0,81	disease	0,83	disease	0,68	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,13	0,56	0,9	3,9	6,77	P	0,49	N	0,76	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6838	6838	T	A	MI.3879	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	935	312	I	N	aTc/aAc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-6,67	deleterious	-4,59	high_impact	5,28	damaging	0,58	damaging	0,09	deleterious	4,58	24,4	0,14	0,55	disease	0,8	disease	0,9	disease	0,69	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,78	0,5	0,9	3,9	6,77	P	0,66	P	0,94	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8708	8708	A	T	MI.388	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	182	61	H	L	cAc/cTc	-0,33	0	0	probably_damaging	0,99	neutral	1	neutral	4,61	neutral	2,99	deleterious	-3,73	neutral_impact	-2,02	neutral	0,78	neutral	0,46	neutral	0,89	10,03	0,41	0,65	neutral	0,4	neutral	0,25	disease	0,53	neutral	0,46	1	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,67	low_impact	-2,65	high_impact	1,98	low_impact	-2,83	0,31	0,9	48,67	8,33	N	0,25	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6839	6839	C	A	MI.3880	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	936	312	I	M	atC/atA	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-5,08	neutral	-1,97	high_impact	4,72	neutral	0,63	damaging	0,09	deleterious	3,95	23,6	0,28	0,55	disease	0,83	disease	0,78	disease	0,61	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,26	0,76	0,9	3,9	6,77	P	0,66	P	0,76	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6839	6839	C	G	MI.3881	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	936	312	I	M	atC/atG	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-5,08	neutral	-1,97	high_impact	4,72	neutral	0,63	damaging	0,09	deleterious	3,46	23	0,28	0,55	disease	0,83	disease	0,78	disease	0,61	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,26	0,76	0,9	3,9	6,77	P	0,66	P	0,76	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6840	6840	G	C	MI.3882	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	937	313	A	P	Gct/Cct	-3,11	0	0	probably_damaging	1	deleterious	0	neutral	2,47	deleterious	-5,23	deleterious	-3,3	high_impact	5,24	damaging	0,58	damaging	0,15	deleterious	3,87	23,5	0,13	0,55	disease	0,84	disease	0,9	disease	0,67	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,76	0,9	4,29	6,68	P	0,66	P	0,85	polymorphism	0,63	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6840	6840	G	T	MI.3883	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	937	313	A	S	Gct/Tct	-3,11	0	0	probably_damaging	0,99	deleterious	0	neutral	2,51	neutral	-2,09	neutral	-1,98	high_impact	3,55	neutral	0,73	damaging	0,17	deleterious	3,77	23,4	0,27	0,55	neutral	0,32	disease	0,89	disease	0,64	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	2,18	0,78	0,9	4,29	6,68	N	0,35	N	0,64	polymorphism	0,93	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6840	6840	G	A	MI.3884	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	937	313	A	T	Gct/Act	-3,11	0	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-3,3	deleterious	-2,64	high_impact	4,88	neutral	0,65	damaging	0,15	deleterious	4,28	24	0,35	0,55	disease	0,68	disease	0,87	disease	0,62	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,41	0,73	0,9	4,29	6,68	P	0,7	P	0,2	polymorphism	0,86	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6841	6841	C	G	MI.3885	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	938	313	A	G	gCt/gGt	4,52	1	0	probably_damaging	0,98	neutral	0,06	neutral	2,45	deleterious	-3,75	deleterious	-2,64	medium_impact	3,08	damaging	0,5	damaging	0,2	deleterious	4,06	23,7	0,21	0,55	disease	0,6	disease	0,85	neutral	0,47	disease	0,51	0	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,83	low_impact	-2,35	medium_impact	-0,47	medium_impact	1,75	0,79	0,9	4,29	6,68	P	0,53	P	0,56	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6841	6841	C	A	MI.3886	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	938	313	A	D	gCt/gAt	4,52	1	0	probably_damaging	1	deleterious	0	neutral	2,4	deleterious	-4,92	deleterious	-3,96	high_impact	5,24	neutral	0,67	damaging	0,14	deleterious	4,53	24,3	0,11	0,55	disease	0,79	disease	0,94	disease	0,77	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,62	0,9	4,29	6,68	P	0,72	P	0,89	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6841	6841	C	T	MI.3887	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	938	313	A	V	gCt/gTt	4,52	1	0	probably_damaging	0,99	deleterious	0	neutral	2,55	neutral	-2,38	deleterious	-2,64	high_impact	4,68	damaging	0,58	damaging	0,13	deleterious	4,49	24,3	0,32	0,55	disease	0,79	disease	0,91	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-2,64	low_impact	-1,48	high_impact	3,22	0,75	0,9	4,29	6,68	P	0,61	P	0,75	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6843	6843	A	T	MI.3888	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	940	314	I	F	Atc/Ttc	-9,13	0	0	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-4,52	deleterious	-2,63	high_impact	4,12	damaging	0,53	damaging	0,07	deleterious	3,98	23,6	0,31	0,55	disease	0,77	disease	0,84	disease	0,68	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,87	0,9	2,34	6,75	N	0,29	N	0,85	polymorphism	0,63	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6843	6843	A	G	MI.3889	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	940	314	I	V	Atc/Gtc	-9,13	0	0	probably_damaging	0,92	neutral	1	neutral	3,15	neutral	0,49	neutral	0,23	neutral_impact	-0,79	damaging	0,52	damaging	0,23	deleterious	0,41	6,69	0,5	0,6	neutral	0,19	neutral	0,06	neutral	0,34	neutral	0,19	6	neutral	0,92	deleterious	0,54	neutral	-2	deleterious	0,52	low_impact	-1,76	high_impact	1,86	low_impact	-1,83	0,77	0,9	2,34	6,75	N	0,33	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8708	8708	A	G	MI.389	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	182	61	H	R	cAc/cGc	-0,33	0	0	probably_damaging	0,99	neutral	0,09	neutral	4,39	neutral	-0,29	deleterious	-4,09	low_impact	1,59	neutral	0,85	damaging	0,1	deleterious	2,76	21,2	0,63	0,7	disease	0,53	disease	0,54	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,78	low_impact	-2,65	medium_impact	-0,28	medium_impact	0,27	0,34	0,9	48,67	8,33	N	0,29	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6843	6843	A	C	MI.3890	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	940	314	I	L	Atc/Ctc	-9,13	0	0	probably_damaging	0,97	deleterious	0	neutral	2,79	neutral	-1,02	neutral	-1,31	medium_impact	2,43	damaging	0,51	damaging	0,08	deleterious	3,9	23,5	0,35	0,55	neutral	0,33	disease	0,63	disease	0,55	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,61	low_impact	-2,18	low_impact	-1,48	medium_impact	1,15	0,83	0,9	2,34	6,75	N	0,32	N	0,61	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6844	6844	T	C	MI.3891	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	941	314	I	T	aTc/aCc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-3,84	neutral	-2,4	high_impact	4,12	damaging	0,48	damaging	0,09	deleterious	3,48	23,1	0,43	0,55	disease	0,74	disease	0,64	disease	0,65	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,68	0,9	2,34	6,75	P	0,5	N	0,76	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6844	6844	T	A	MI.3892	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	941	314	I	N	aTc/aAc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-6,6	deleterious	-4,16	high_impact	4,12	damaging	0,48	damaging	0,09	deleterious	4,49	24,3	0,3	0,55	disease	0,92	disease	0,88	disease	0,68	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,75	0,9	2,34	6,75	N	0,48	N	0,94	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6844	6844	T	G	MI.3893	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	941	314	I	S	aTc/aGc	7,07	1	0	probably_damaging	1	deleterious	0,02	neutral	2,57	deleterious	-4,29	deleterious	-3,5	high_impact	4,12	damaging	0,47	damaging	0,13	deleterious	4,34	24	0,27	0,55	disease	0,85	disease	0,84	disease	0,65	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-3,58	medium_impact	-0,75	high_impact	2,71	0,65	0,9	2,34	6,75	P	0,53	P	0,62	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6845	6845	C	G	MI.3894	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	942	314	I	M	atC/atG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-3,26	neutral	-1,53	high_impact	3,56	damaging	0,54	damaging	0,08	deleterious	3,5	23,1	0,41	0,55	disease	0,52	disease	0,62	disease	0,67	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	high_impact	2,19	0,93	0,95	2,34	6,75	N	0,46	N	0,76	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6845	6845	C	A	MI.3895	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	942	314	I	M	atC/atA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-3,26	neutral	-1,53	high_impact	3,56	damaging	0,54	damaging	0,08	deleterious	3,94	23,5	0,41	0,55	disease	0,52	disease	0,62	disease	0,67	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	high_impact	2,19	0,93	0,95	2,34	6,75	N	0,46	N	0,76	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6846	6846	C	A	MI.3896	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	943	315	P	T	Ccc/Acc	-3,11	0	0	probably_damaging	1	deleterious	0	neutral	0,47	deleterious	-8,06	deleterious	-5,24	high_impact	4,94	neutral	0,72	damaging	0,05	deleterious	3,77	23,4	0,29	0,55	disease	0,96	disease	0,83	disease	0,73	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,46	0,66	0,9	2,34	6,64	P	0,59	P	0,8	disease_causing	0,66	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6846	6846	C	T	MI.3897	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	943	315	P	S	Ccc/Tcc	-3,11	0	0	probably_damaging	1	deleterious	0	neutral	0,47	deleterious	-8,3	deleterious	-5,24	high_impact	4,94	neutral	0,73	damaging	0,05	deleterious	3,98	23,6	0,37	0,55	disease	0,95	disease	0,87	disease	0,73	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,46	0,31	0,9	2,34	6,64	P	0,61	P	0,85	disease_causing	0,67	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6846	6846	C	G	MI.3898	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	943	315	P	A	Ccc/Gcc	-3,11	0	0	probably_damaging	1	deleterious	0	neutral	0,48	deleterious	-7,43	deleterious	-5,24	high_impact	5,29	neutral	0,71	damaging	0,07	deleterious	3,19	22,7	0,26	0,55	disease	0,94	disease	0,72	disease	0,73	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,68	0,9	2,34	6,64	P	0,59	P	0,76	disease_causing	0,55	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6847	6847	C	T	MI.3899	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	944	315	P	L	cCc/cTc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	0,46	deleterious	-8,94	deleterious	-6,55	high_impact	4,94	neutral	0,71	damaging	0,03	deleterious	4,5	24,3	0,31	0,55	disease	0,97	disease	0,89	disease	0,71	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,46	0,7	0,9	2,34	6,64	P	0,62	P	0,87	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8543	8543	T	A	MI.39	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	17	6	F	Y	tTc/tAc	4,76	1	0	probably_damaging	0,92	deleterious	0	neutral	4,01	neutral	-1,33	deleterious	-2,52	medium_impact	3,32	damaging	0,58	neutral	0,54	deleterious	4,13	23,8	0,41	0,65	neutral	0,35	disease	0,62	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,72	low_impact	-1,76	low_impact	-1,4	medium_impact	1,75	0,48	0,9	39,82	8,43	P	0,62	P	0,89	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8708	8708	A	C	MI.390	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	182	61	H	P	cAc/cCc	-0,33	0	0	probably_damaging	0,99	neutral	0,07	neutral	4,38	neutral	-0,9	deleterious	-5,46	low_impact	1,25	neutral	0,78	damaging	0,08	deleterious	3,07	22,4	0,35	0,65	neutral	0,43	disease	0,8	disease	0,79	disease	0,77	5	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,8	low_impact	-2,65	medium_impact	-0,34	medium_impact	-0,03	0,33	0,9	48,67	8,33	N	0,25	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6847	6847	C	A	MI.3900	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	944	315	P	H	cCc/cAc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	0,45	deleterious	-10,45	deleterious	-5,9	high_impact	4,74	neutral	0,72	damaging	0,04	deleterious	4,12	23,8	0,24	0,55	disease	0,98	disease	0,88	disease	0,82	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,28	0,66	0,9	2,34	6,64	P	0,6	P	0,81	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6847	6847	C	G	MI.3901	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	944	315	P	R	cCc/cGc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	0,45	deleterious	-9,57	deleterious	-5,9	high_impact	5,29	neutral	0,72	damaging	0,04	deleterious	3,68	23,3	0,21	0,55	disease	0,97	disease	0,92	disease	0,83	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,59	0,9	2,34	6,64	P	0,62	P	0,9	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6849	6849	A	C	MI.3902	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	946	316	T	P	Acc/Ccc	-10,75	0	0	probably_damaging	0,91	deleterious	0	neutral	2,63	deleterious	-4,1	deleterious	-3,93	high_impact	4,72	damaging	0,52	damaging	0,17	deleterious	4,11	23,7	0,17	0,55	disease	0,88	disease	0,86	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,83	low_impact	-1,7	low_impact	-1,48	high_impact	3,26	0,42	0,9	2,34	7,13	P	0,62	P	0,92	disease_causing	0,77	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6849	6849	A	G	MI.3903	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	946	316	T	A	Acc/Gcc	-10,75	0	0	benign	0,18	deleterious	0	neutral	2,68	neutral	-2,64	deleterious	-3,27	high_impact	5,28	neutral	0,8	damaging	0,14	deleterious	4,11	23,8	0,35	0,55	disease	0,53	disease	0,7	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,41	deleterious	2	neutral	0,36	medium_impact	-0,14	low_impact	-1,48	high_impact	3,78	0,45	0,9	2,34	7,13	N	0,57	P	0,69	polymorphism	0,6	0,27	.	.	.	.	.	lymphoblast cell line	.	.	.	.	.	.	.	.	.
chrM	6849	6849	A	T	MI.3904	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	946	316	T	S	Acc/Tcc	-10,75	0	0	benign	0,37	deleterious	0,04	neutral	2,85	neutral	-0,76	deleterious	-2,62	high_impact	3,89	neutral	0,76	damaging	0,16	deleterious	3,96	23,6	0,3	0,55	neutral	0,44	disease	0,8	disease	0,65	disease	0,67	3	neutral	0,95	neutral	0,34	deleterious	2	deleterious	0,47	medium_impact	-0,54	medium_impact	-0,58	high_impact	2,49	0,54	0,9	2,34	7,13	N	0,35	N	0,79	polymorphism	0,82	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6850	6850	C	G	MI.3905	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	947	316	T	S	aCc/aGc	8,69	1	0	benign	0,37	deleterious	0,04	neutral	2,85	neutral	-0,76	deleterious	-2,62	high_impact	3,89	neutral	0,76	damaging	0,16	deleterious	3,6	23,2	0,3	0,55	neutral	0,44	disease	0,8	disease	0,65	disease	0,67	3	neutral	0,95	neutral	0,34	deleterious	2	deleterious	0,47	medium_impact	-0,54	medium_impact	-0,58	high_impact	2,49	0,54	0,9	2,34	7,13	P	0,53	P	0,79	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6850	6850	C	T	MI.3906	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	947	316	T	I	aCc/aTc	8,69	1	0	benign	0,04	deleterious	0	neutral	2,68	neutral	-2,59	deleterious	-3,93	high_impact	5,28	damaging	0,59	damaging	0,15	deleterious	4,06	23,7	0,29	0,55	disease	0,91	disease	0,91	disease	0,65	disease	0,77	5	deleterious	1	deleterious	0,48	deleterious	2	neutral	0,35	medium_impact	0,54	low_impact	-1,48	high_impact	3,78	0,5	0,9	2,34	7,13	P	0,66	P	0,92	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6850	6850	C	A	MI.3907	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	947	316	T	N	aCc/aAc	8,69	1	0	possibly_damaging	0,87	deleterious	0	neutral	2,63	deleterious	-4,2	deleterious	-3,27	high_impact	4,93	neutral	0,64	damaging	0,11	deleterious	3,74	23,3	0,35	0,55	disease	0,87	disease	0,86	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,81	low_impact	-1,53	low_impact	-1,48	high_impact	3,45	0,75	0,9	2,34	7,13	P	0,73	P	0,8	disease_causing	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6852	6852	G	C	MI.3908	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	949	317	G	R	Ggc/Cgc	-13,06	0	0	probably_damaging	1	deleterious	0	neutral	2,68	deleterious	-3,37	deleterious	-5,25	high_impact	5,26	damaging	0,48	damaging	0,15	deleterious	4,04	23,7	0,17	0,55	disease	0,73	disease	0,9	disease	0,8	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,78	0,9	1,95	6,99	P	0,65	P	0,95	polymorphism	0,65	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6852	6852	G	T	MI.3909	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	949	317	G	C	Ggc/Tgc	-13,06	0	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-3,84	deleterious	-5,9	high_impact	4,58	damaging	0,44	damaging	0,15	deleterious	4,23	23,9	0,15	0,55	disease	0,81	disease	0,89	disease	0,71	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,13	0,55	0,9	1,95	6,99	N	0,46	N	0,98	disease_causing	0,52	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8709	8709	C	G	MI.391	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	183	61	H	Q	caC/caG	6,14	0,87	0	probably_damaging	0,99	neutral	0,06	neutral	4,38	neutral	-0,44	deleterious	-4,06	low_impact	1,04	neutral	0,88	damaging	0,26	deleterious	3,39	23	0,62	0,7	disease	0,56	neutral	0,41	disease	0,69	disease	0,65	3	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,73	low_impact	-2,65	medium_impact	-0,38	medium_impact	-0,21	0,44	0,9	48,67	8,33	N	0,47	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6852	6852	G	A	MI.3910	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	949	317	G	S	Ggc/Agc	-13,06	0	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-2,97	deleterious	-3,93	high_impact	4,12	damaging	0,44	damaging	0,24	deleterious	4,25	23,9	0,2	0,55	disease	0,59	disease	0,84	disease	0,63	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,56	0,9	1,95	6,99	N	0,42	N	0,73	polymorphism	0,79	0,28	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	6853	6853	G	C	MI.3911	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	950	317	G	A	gGc/gCc	7,53	1	0	probably_damaging	1	deleterious	0,04	neutral	2,75	neutral	-1,92	deleterious	-3,93	high_impact	3,82	damaging	0,51	neutral	0,33	deleterious	3,24	22,8	0,23	0,55	neutral	0,41	disease	0,69	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-3,58	medium_impact	-0,58	high_impact	2,43	0,68	0,9	1,95	6,99	P	0,52	P	0,64	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6853	6853	G	T	MI.3912	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	950	317	G	V	gGc/gTc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,8	neutral	-1,31	deleterious	-5,9	high_impact	5,26	damaging	0,47	damaging	0,19	deleterious	3,88	23,5	0,15	0,55	neutral	0,47	disease	0,89	disease	0,7	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,54	0,9	1,95	6,99	P	0,71	P	0,93	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6853	6853	G	A	MI.3913	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	950	317	G	D	gGc/gAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-4,14	deleterious	-4,59	high_impact	4,92	damaging	0,43	damaging	0,17	deleterious	3,89	23,5	0,16	0,55	disease	0,8	disease	0,88	disease	0,79	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,35	0,9	1,95	6,99	P	0,82	P	0,97	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6855	6855	G	A	MI.3914	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	952	318	V	I	Gtc/Atc	-11,67	0	0	probably_damaging	0,97	neutral	1	neutral	2,8	neutral	-0,43	neutral	0,57	neutral_impact	-1,62	neutral	0,64	neutral	0,29	neutral	-0,95	0,02	0,47	0,55	neutral	0,16	neutral	0,07	neutral	0,18	neutral	0,25	5	neutral	0,97	deleterious	0,52	neutral	-2	deleterious	0,58	low_impact	-2,18	high_impact	1,86	low_impact	-2,6	0,86	0,9	3,51	7,96	N	0,35	N	0,24	polymorphism	1	0,01	.	.	.	.	.	pituitary oncocytoma	.	.	.	.	.	.	.	.	.
chrM	6855	6855	G	T	MI.3915	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	952	318	V	F	Gtc/Ttc	-11,67	0	0	probably_damaging	1	deleterious	0	neutral	2,62	neutral	-2,74	neutral	-2,05	medium_impact	2,77	neutral	0,61	damaging	0,12	deleterious	3,87	23,5	0,15	0,55	disease	0,64	disease	0,9	disease	0,57	disease	0,76	5	deleterious	1	deleterious	0	deleterious	5	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	medium_impact	1,46	0,79	0,9	3,51	7,96	N	0,25	N	0,86	polymorphism	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6855	6855	G	C	MI.3916	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	952	318	V	L	Gtc/Ctc	-11,67	0	0	probably_damaging	0,97	deleterious	0	neutral	2,86	neutral	-0,6	neutral	-0,74	medium_impact	2,77	neutral	0,68	damaging	0,13	neutral	1,77	14,81	0,38	0,55	neutral	0,41	disease	0,7	neutral	0,42	neutral	0,49	0	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,76	low_impact	-2,18	low_impact	-1,48	medium_impact	1,46	0,79	0,9	3,51	7,96	N	0,35	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6856	6856	T	G	MI.3917	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	953	318	V	G	gTc/gGc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-4,26	deleterious	-4,59	medium_impact	3,46	neutral	0,64	damaging	0,17	deleterious	3,89	23,5	0,13	0,55	disease	0,76	disease	0,81	disease	0,56	disease	0,72	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,1	0,64	0,9	3,51	7,96	N	0,46	N	0,71	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6856	6856	T	C	MI.3918	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	953	318	V	A	gTc/gCc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,74	neutral	-1,99	deleterious	-2,62	medium_impact	3,46	neutral	0,64	damaging	0,16	deleterious	3,4	23	0,31	0,55	neutral	0,28	disease	0,57	disease	0,55	disease	0,66	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,71	low_impact	-3,58	low_impact	-1,48	high_impact	2,1	0,64	0,9	3,51	7,96	P	0,5	N	0,47	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6856	6856	T	A	MI.3919	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	953	318	V	D	gTc/gAc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-5,38	deleterious	-3,97	medium_impact	3,46	neutral	0,61	damaging	0,14	deleterious	4,51	24,3	0,08	0,55	disease	0,85	disease	0,9	disease	0,68	disease	0,73	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,1	0,76	0,9	3,51	7,96	N	0,46	N	0,83	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8709	8709	C	A	MI.392	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	183	61	H	Q	caC/caA	6,14	0,87	0	probably_damaging	0,99	neutral	0,06	neutral	4,38	neutral	-0,44	deleterious	-4,06	low_impact	1,04	neutral	0,88	damaging	0,26	deleterious	3,77	23,4	0,62	0,7	disease	0,56	neutral	0,41	disease	0,69	disease	0,65	3	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,73	low_impact	-2,65	medium_impact	-0,38	medium_impact	-0,21	0,44	0,9	48,67	8,33	N	0,47	N	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6858	6858	A	G	MI.3920	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	955	319	K	E	Aaa/Gaa	-9,13	0	0	benign	0,33	deleterious	0	neutral	2,68	neutral	-2,21	deleterious	-2,56	high_impact	5,28	damaging	0,51	neutral	0,51	deleterious	4,11	23,7	0,31	0,55	disease	0,66	disease	0,9	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,84	medium_impact	-0,47	low_impact	-1,48	high_impact	3,78	0,66	0,9	2,34	6,86	P	0,66	P	0,75	polymorphism	0,98	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6858	6858	A	C	MI.3921	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	955	319	K	Q	Aaa/Caa	-9,13	0	0	benign	0,39	deleterious	0	neutral	2,69	neutral	-2,33	deleterious	-2,56	high_impact	4,72	neutral	0,65	neutral	0,55	deleterious	3,54	23,1	0,39	0,55	disease	0,55	disease	0,84	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,79	medium_impact	-0,57	low_impact	-1,48	high_impact	3,26	0,73	0,9	2,34	6,86	P	0,64	P	0,64	polymorphism	0,99	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6859	6859	A	C	MI.3922	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	956	319	K	T	aAa/aCa	8,69	1	0	benign	0,03	deleterious	0	neutral	2,82	neutral	-1,23	deleterious	-3,83	high_impact	5,28	neutral	0,61	neutral	0,52	deleterious	3,79	23,4	0,24	0,55	neutral	0,34	disease	0,85	disease	0,66	disease	0,71	4	deleterious	1	deleterious	0,49	deleterious	2	neutral	0,37	medium_impact	0,66	low_impact	-1,48	high_impact	3,78	0,55	0,9	2,34	6,86	P	0,65	P	0,76	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6859	6859	A	T	MI.3923	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	956	319	K	M	aAa/aTa	8,69	1	0	possibly_damaging	0,89	deleterious	0	neutral	2,72	deleterious	-4,18	deleterious	-3,86	high_impact	4,72	neutral	0,67	neutral	0,58	deleterious	4,07	23,7	0,19	0,55	disease	0,89	disease	0,86	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,06	deleterious	5	deleterious	0,85	low_impact	-1,61	low_impact	-1,48	high_impact	3,26	0,55	0,9	2,34	6,86	P	0,72	P	0,89	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6860	6860	A	C	MI.3924	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	957	319	K	N	aaA/aaC	8,69	1	0	possibly_damaging	0,54	deleterious	0	neutral	2,67	deleterious	-3,15	deleterious	-3,19	high_impact	4,93	damaging	0,57	neutral	0,46	deleterious	3,83	23,4	0,44	0,55	disease	0,74	disease	0,84	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,23	deleterious	5	deleterious	0,85	medium_impact	-0,82	low_impact	-1,48	high_impact	3,45	0,7	0,9	2,34	6,86	P	0,68	P	0,76	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6860	6860	A	T	MI.3925	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	957	319	K	N	aaA/aaT	8,69	1	0	possibly_damaging	0,54	deleterious	0	neutral	2,67	deleterious	-3,15	deleterious	-3,19	high_impact	4,93	damaging	0,57	neutral	0,46	deleterious	4,02	23,6	0,44	0,55	disease	0,74	disease	0,84	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,23	deleterious	5	deleterious	0,85	medium_impact	-0,82	low_impact	-1,48	high_impact	3,45	0,7	0,9	2,34	6,86	P	0,69	P	0,76	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6861	6861	G	T	MI.3926	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	958	320	V	L	Gta/Tta	4,76	1	0	probably_damaging	0,99	deleterious	0	neutral	2,57	neutral	-1,43	neutral	-1,24	medium_impact	3,29	damaging	0,57	damaging	0,11	deleterious	1,89	15,52	0,43	0,55	neutral	0,42	disease	0,79	neutral	0,5	disease	0,62	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	medium_impact	1,94	0,8	0,9	3,51	7,73	N	0,46	N	0,55	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6861	6861	G	C	MI.3927	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	958	320	V	L	Gta/Cta	4,76	1	0	probably_damaging	0,99	deleterious	0	neutral	2,57	neutral	-1,43	neutral	-1,24	medium_impact	3,29	damaging	0,57	damaging	0,11	neutral	1,77	14,8	0,43	0,55	neutral	0,42	disease	0,79	neutral	0,5	disease	0,62	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	medium_impact	1,94	0,8	0,9	3,51	7,73	N	0,43	N	0,55	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6861	6861	G	A	MI.3928	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	958	320	V	M	Gta/Ata	4,76	1	0	probably_damaging	1	deleterious	0	neutral	2,53	neutral	-1,78	neutral	-1,6	medium_impact	3,29	damaging	0,6	damaging	0,15	deleterious	3,81	23,4	0,41	0,55	disease	0,69	disease	0,74	disease	0,51	neutral	0,47	1	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	medium_impact	1,94	0,8	0,9	3,51	7,73	N	0,43	N	0,82	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6862	6862	T	C	MI.3929	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	959	320	V	A	gTa/gCa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,54	neutral	-1,77	deleterious	-2,6	high_impact	4,26	damaging	0,59	damaging	0,16	deleterious	3,62	23,2	0,34	0,55	neutral	0,45	disease	0,68	disease	0,58	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,83	0,68	0,9	3,51	7,73	P	0,51	P	0,47	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8710	8710	A	C	MI.393	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	184	62	N	H	Aac/Cac	-4,5	0	0	possibly_damaging	0,8	neutral	0,1	neutral	4,38	neutral	-0,25	deleterious	-4,11	medium_impact	2,81	neutral	0,82	neutral	0,62	deleterious	2,73	21	0,86	0,9	disease	0,56	disease	0,73	neutral	0,35	disease	0,5	0	neutral	0,94	neutral	0,15	NA	0	deleterious	0,67	low_impact	-1,33	medium_impact	-0,25	medium_impact	1,31	0,64	0,9	18,14	14,91	N	0,35	N	0,5	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6862	6862	T	A	MI.3930	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	959	320	V	E	gTa/gAa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-4,65	deleterious	-3,92	high_impact	4,26	damaging	0,59	damaging	0,16	deleterious	4,9	24,9	0,09	0,55	disease	0,83	disease	0,93	disease	0,7	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	2,83	0,5	0,9	3,51	7,73	N	0,5	N	0,84	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6862	6862	T	G	MI.3931	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	959	320	V	G	gTa/gGa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-3,78	deleterious	-4,57	high_impact	3,91	damaging	0,6	damaging	0,15	deleterious	3,9	23,5	0,13	0,55	disease	0,82	disease	0,85	disease	0,63	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,51	0,7	0,9	3,51	7,73	N	0,46	N	0,71	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6864	6864	T	G	MI.3932	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	961	321	F	V	Ttt/Gtt	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	2,55	neutral	-2,8	deleterious	-4,58	high_impact	4,22	neutral	0,72	damaging	0,06	deleterious	4,04	23,7	0,17	0,55	disease	0,53	disease	0,87	disease	0,66	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,8	0,66	0,9	3,31	6,68	N	0,34	N	0,84	polymorphism	0,78	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6864	6864	T	A	MI.3933	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	961	321	F	I	Ttt/Att	-6,12	0	0	probably_damaging	0,99	deleterious	0	neutral	2,51	deleterious	-3	deleterious	-3,92	high_impact	4,92	neutral	0,74	damaging	0,07	deleterious	4,42	24,2	0,16	0,55	disease	0,68	disease	0,83	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,64	low_impact	-1,48	high_impact	3,44	0,64	0,9	3,31	6,68	P	0,62	P	0,88	polymorphism	0,88	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6864	6864	T	C	MI.3934	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	961	321	F	L	Ttt/Ctt	-6,12	0	0	probably_damaging	0,98	deleterious	0	neutral	2,53	neutral	-2,13	deleterious	-3,92	high_impact	4,03	neutral	0,74	damaging	0,05	deleterious	4,07	23,7	0,31	0,55	disease	0,6	disease	0,79	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,35	low_impact	-1,48	high_impact	2,62	0,72	0,9	3,31	6,68	N	0,28	N	0,83	polymorphism	0,87	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6865	6865	T	A	MI.3935	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	962	321	F	Y	tTt/tAt	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,39	deleterious	-3,49	neutral	-1,96	high_impact	4,23	neutral	0,74	damaging	0,06	deleterious	4,42	24,2	0,18	0,55	disease	0,7	disease	0,8	disease	0,61	disease	0,59	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,35	low_impact	-1,48	high_impact	2,81	0,68	0,9	3,31	6,68	P	0,55	P	0,59	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6865	6865	T	G	MI.3936	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	962	321	F	C	tTt/tGt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,37	deleterious	-5,59	deleterious	-5,23	high_impact	5,27	neutral	0,72	damaging	0,05	deleterious	4,18	23,8	0,14	0,55	disease	0,91	disease	0,86	disease	0,68	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,77	0,44	0,9	3,31	6,68	P	0,68	P	0,91	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6865	6865	T	C	MI.3937	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	962	321	F	S	tTt/tCt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,38	deleterious	-4,19	deleterious	-5,23	high_impact	4,58	neutral	0,74	damaging	0,08	deleterious	4,39	24,1	0,13	0,55	disease	0,77	disease	0,86	disease	0,64	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,13	0,6	0,9	3,31	6,68	P	0,53	P	0,84	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6866	6866	T	A	MI.3938	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	963	321	F	L	ttT/ttA	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,53	neutral	-2,13	deleterious	-3,92	high_impact	4,03	neutral	0,74	damaging	0,05	deleterious	4,55	24,4	0,31	0,55	disease	0,6	disease	0,79	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,35	low_impact	-1,48	high_impact	2,62	0,72	0,9	3,31	6,68	P	0,57	P	0,83	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6866	6866	T	G	MI.3939	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	963	321	F	L	ttT/ttG	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,53	neutral	-2,13	deleterious	-3,92	high_impact	4,03	neutral	0,74	damaging	0,05	deleterious	4,51	24,3	0,31	0,55	disease	0,6	disease	0,79	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,35	low_impact	-1,48	high_impact	2,62	0,72	0,9	3,31	6,68	P	0,56	P	0,83	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8710	8710	A	G	MI.394	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	184	62	N	D	Aac/Gac	-4,5	0	0	benign	0,19	neutral	0,18	neutral	4,41	neutral	0,28	deleterious	-3,9	medium_impact	2,46	neutral	0,75	neutral	0,58	deleterious	1,85	15,28	0,9	0,95	neutral	0,45	disease	0,73	disease	0,54	disease	0,57	1	neutral	0,79	deleterious	0,5	neutral	-3	neutral	0,34	medium_impact	-0,16	medium_impact	-0,08	medium_impact	1,01	0,74	0,9	18,14	14,91	N	0,38	N	0,55	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6867	6867	A	G	MI.3940	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	964	322	S	G	Agc/Ggc	-3,11	0	0	probably_damaging	0,99	neutral	0,05	neutral	2,81	neutral	-1,49	deleterious	-2,59	high_impact	4,49	damaging	0,43	damaging	0,09	deleterious	3,65	23,2	0,28	0,55	disease	0,59	disease	0,69	disease	0,57	disease	0,64	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,77	low_impact	-2,64	medium_impact	-0,52	high_impact	3,05	0,72	0,9	1,75	6,66	N	0,45	N	0,7	polymorphism	0,75	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6867	6867	A	C	MI.3941	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	964	322	S	R	Agc/Cgc	-3,11	0	0	probably_damaging	1	deleterious	0,02	neutral	2,78	neutral	-1,86	deleterious	-3,26	high_impact	5,18	damaging	0,54	damaging	0,02	deleterious	3,9	23,5	0,15	0,55	disease	0,61	disease	0,87	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-3,58	medium_impact	-0,75	high_impact	3,68	0,77	0,9	1,75	6,66	P	0,66	P	0,98	disease_causing	0,63	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6867	6867	A	T	MI.3942	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	964	322	S	C	Agc/Tgc	-3,11	0	0	probably_damaging	1	deleterious	0	neutral	2,75	deleterious	-3,81	deleterious	-3,26	high_impact	5,18	damaging	0,51	damaging	0,02	deleterious	3,49	23,1	0,2	0,55	disease	0,53	disease	0,83	disease	0,62	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,65	0,9	1,75	6,66	P	0,6	P	0,85	disease_causing	0,58	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6868	6868	G	T	MI.3943	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	965	322	S	I	aGc/aTc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,79	neutral	-2,07	deleterious	-3,91	high_impact	5,18	damaging	0,55	damaging	0,04	deleterious	4,2	23,9	0,17	0,55	disease	0,72	disease	0,9	disease	0,64	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,75	0,9	1,75	6,66	P	0,72	P	0,96	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6868	6868	G	C	MI.3944	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	965	322	S	T	aGc/aCc	8,69	1	0	probably_damaging	0,97	deleterious	0	neutral	2,83	neutral	-0,64	neutral	-1,96	high_impact	4,21	damaging	0,53	damaging	0,04	deleterious	3,44	23	0,25	0,55	neutral	0,35	disease	0,73	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,77	low_impact	-2,18	low_impact	-1,48	high_impact	2,79	0,78	0,9	1,75	6,66	P	0,5	N	0,43	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6868	6868	G	A	MI.3945	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	965	322	S	N	aGc/aAc	8,69	1	0	probably_damaging	0,97	neutral	0,06	neutral	3,09	neutral	0,95	neutral	-1,95	medium_impact	2,51	damaging	0,47	damaging	0,04	deleterious	3,65	23,2	0,48	0,55	neutral	0,17	disease	0,79	disease	0,55	disease	0,56	1	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,72	low_impact	-2,18	medium_impact	-0,47	medium_impact	1,22	0,58	0,9	1,75	6,66	P	0,55	P	0,66	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6870	6870	T	C	MI.3946	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	967	323	W	R	Tga/Cga	0,13	0,98	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-3,8	deleterious	-9,15	high_impact	4,74	neutral	0,62	damaging	0,04	deleterious	3,66	23,2	0,19	0,55	disease	0,93	disease	0,93	disease	0,79	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,28	0,28	0,9	1,36	6,89	P	0,6	P	0,98	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6870	6870	T	G	MI.3947	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	967	323	W	G	Tga/Gga	0,13	0,98	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-4,03	deleterious	-8,49	high_impact	5,29	neutral	0,66	damaging	0,05	deleterious	3,99	23,6	0,15	0,55	disease	0,94	disease	0,88	disease	0,77	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,23	0,9	1,36	6,89	P	0,6	P	0,89	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6871	6871	G	T	MI.3948	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	968	323	W	L	tGa/tTa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,68	neutral	-1,21	deleterious	-8,49	high_impact	4,93	neutral	0,69	damaging	0,04	deleterious	4,32	24	0,15	0,55	disease	0,61	disease	0,87	disease	0,75	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,2	0,9	1,36	6,89	P	0,7	P	0,95	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6871	6871	G	C	MI.3949	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	968	323	W	S	tGa/tCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-3,08	deleterious	-9,14	high_impact	4,93	neutral	0,65	damaging	0,06	deleterious	4,11	23,7	0,15	0,55	disease	0,9	disease	0,93	disease	0,76	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,22	0,9	1,36	6,89	P	0,63	P	0,89	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8710	8710	A	T	MI.395	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	184	62	N	Y	Aac/Tac	-4,5	0	0	possibly_damaging	0,8	neutral	0,15	neutral	4,3	neutral	-2,6	deleterious	-6,55	medium_impact	3,06	neutral	0,8	neutral	0,42	deleterious	3,29	22,8	0,57	0,65	disease	0,56	disease	0,83	neutral	0,45	disease	0,71	4	neutral	0,91	neutral	0,18	NA	0	deleterious	0,72	low_impact	-1,33	medium_impact	-0,13	medium_impact	1,53	0,62	0,9	18,14	14,91	N	0,33	N	0,89	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6872	6872	A	T	MI.3950	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	969	323	W	C	tgA/tgT	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-4,66	deleterious	-8,49	high_impact	5,29	damaging	0,59	damaging	0,05	deleterious	4,21	23,9	0,19	0,55	disease	0,96	disease	0,93	disease	0,81	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,27	0,9	1,36	6,89	P	0,61	P	0,88	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6872	6872	A	C	MI.3951	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	969	323	W	C	tgA/tgC	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-4,66	deleterious	-8,49	high_impact	5,29	damaging	0,59	damaging	0,05	deleterious	4,09	23,7	0,19	0,55	disease	0,96	disease	0,93	disease	0,81	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,79	0,27	0,9	1,36	6,89	P	0,61	P	0,88	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6873	6873	C	G	MI.3952	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	970	324	L	V	Ctc/Gtc	0,59	0,11	0	probably_damaging	0,99	deleterious	0,02	neutral	2,64	neutral	-0,99	neutral	-1,37	medium_impact	2,42	damaging	0,56	damaging	0,07	deleterious	3,51	23,1	0,33	0,55	neutral	0,31	disease	0,63	neutral	0,32	neutral	0,21	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,73	low_impact	-2,64	medium_impact	-0,75	medium_impact	1,14	0,76	0,9	2,14	6,81	N	0,33	N	0,66	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6873	6873	C	A	MI.3953	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	970	324	L	I	Ctc/Atc	0,59	0,11	0	probably_damaging	1	neutral	0,12	neutral	2,72	neutral	-0,4	neutral	-0,91	low_impact	1,46	damaging	0,57	damaging	0,09	deleterious	4,08	23,7	0,27	0,55	neutral	0,26	neutral	0,4	neutral	0,25	neutral	0,43	1	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,72	low_impact	-3,58	medium_impact	-0,29	medium_impact	0,25	0,86	0,9	2,14	6,81	N	0,37	N	0,54	disease_causing	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6873	6873	C	T	MI.3954	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	970	324	L	F	Ctc/Ttc	0,59	0,11	0	probably_damaging	1	deleterious	0	neutral	2,62	neutral	-2,31	neutral	-2,15	high_impact	3,92	damaging	0,52	damaging	0,05	deleterious	4,1	23,7	0,35	0,55	disease	0,68	disease	0,74	neutral	0,45	neutral	0,41	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,52	0,83	0,9	2,14	6,81	N	0,34	N	0,87	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6874	6874	T	A	MI.3955	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	971	324	L	H	cTc/cAc	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-4,7	deleterious	-3,9	high_impact	4,47	damaging	0,56	damaging	0,04	deleterious	4,33	24	0,11	0,55	disease	0,88	disease	0,84	disease	0,62	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,03	0,64	0,9	2,14	6,81	N	0,35	N	0,83	disease_causing	0,98	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6874	6874	T	C	MI.3956	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	971	324	L	P	cTc/cCc	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-4,75	deleterious	-3,88	high_impact	4,82	damaging	0,47	damaging	0,05	deleterious	4,04	23,7	0,11	0,55	disease	0,87	disease	0,88	disease	0,66	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,58	low_impact	-1,48	high_impact	3,35	0,72	0,9	2,14	6,81	P	0,57	P	0,83	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6874	6874	T	G	MI.3957	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	971	324	L	R	cTc/cGc	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-4,17	deleterious	-3,3	high_impact	4,82	damaging	0,53	damaging	0,04	deleterious	4,32	24	0,1	0,55	disease	0,83	disease	0,9	disease	0,66	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,35	0,55	0,9	2,14	6,81	P	0,63	P	0,9	disease_causing	0,99	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6876	6876	G	T	MI.3958	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	973	325	A	S	Gcc/Tcc	-1,95	0	0	probably_damaging	1	neutral	0,08	neutral	2,74	neutral	-2,56	neutral	-1,65	low_impact	1,61	neutral	0,63	damaging	0,2	deleterious	3,71	23,3	0,29	0,55	neutral	0,46	disease	0,76	neutral	0,33	neutral	0,23	5	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,8	low_impact	-3,58	medium_impact	-0,4	medium_impact	0,39	0,81	0,9	3,9	7,44	N	0,32	N	0,64	disease_causing	0,97	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6876	6876	G	C	MI.3959	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	973	325	A	P	Gcc/Ccc	-1,95	0	0	probably_damaging	1	deleterious	0,01	neutral	2,68	deleterious	-4,63	deleterious	-2,98	high_impact	4,88	damaging	0,5	damaging	0,15	deleterious	3,9	23,5	0,09	0,55	neutral	0,33	disease	0,87	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-3,58	medium_impact	-0,92	high_impact	3,41	0,78	0,9	3,9	7,44	P	0,61	P	0,85	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8711	8711	A	T	MI.396	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	185	62	N	I	aAc/aTc	1,29	0	0	possibly_damaging	0,74	neutral	0,14	neutral	4,31	neutral	-2,31	deleterious	-7,31	medium_impact	2,81	neutral	0,78	neutral	0,48	deleterious	3,59	23,2	0,46	0,65	disease	0,73	disease	0,87	disease	0,51	disease	0,64	3	neutral	0,9	neutral	0,2	NA	0	deleterious	0,67	low_impact	-1,19	medium_impact	-0,15	medium_impact	1,31	0,51	0,9	18,14	14,91	N	0,34	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6876	6876	G	A	MI.3960	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	973	325	A	T	Gcc/Acc	-1,95	0	0	probably_damaging	1	deleterious	0,03	neutral	2,74	neutral	-1,98	neutral	-2,28	medium_impact	2,6	damaging	0,46	damaging	0,2	deleterious	4,3	24	0,33	0,55	disease	0,51	disease	0,78	neutral	0,47	neutral	0,26	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,82	low_impact	-3,58	medium_impact	-0,65	medium_impact	1,3	0,81	0,9	3,9	7,44	N	0,37	N	0,2	disease_causing	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6877	6877	C	A	MI.3961	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	974	325	A	D	gCc/gAc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,68	deleterious	-4,28	deleterious	-3,5	high_impact	4,54	damaging	0,56	damaging	0,13	deleterious	4,63	24,5	0,12	0,55	disease	0,73	disease	0,9	disease	0,67	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,09	0,7	0,9	3,9	7,44	P	0,53	P	0,89	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6877	6877	C	G	MI.3962	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	974	325	A	G	gCc/gGc	9,15	1	0	probably_damaging	1	neutral	0,09	neutral	2,73	neutral	-2,23	neutral	-2,11	low_impact	1,81	damaging	0,43	damaging	0,2	deleterious	2,99	22,2	0,27	0,55	neutral	0,38	disease	0,67	neutral	0,35	neutral	0,22	6	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,75	low_impact	-3,58	medium_impact	-0,37	medium_impact	0,57	0,81	0,9	3,9	7,44	P	0,66	P	0,56	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6877	6877	C	T	MI.3963	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	974	325	A	V	gCc/gTc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,75	neutral	-2,21	neutral	-2,4	high_impact	4,19	damaging	0,51	damaging	0,12	deleterious	4,61	24,4	0,25	0,55	neutral	0,43	disease	0,81	disease	0,56	disease	0,64	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,77	0,83	0,9	3,9	7,44	P	0,55	P	0,75	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6879	6879	A	C	MI.3964	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	976	326	T	P	Aca/Cca	-13,06	0	0	probably_damaging	1	deleterious	0	neutral	2,4	deleterious	-4,88	deleterious	-3,9	high_impact	5,21	damaging	0,54	damaging	0,05	deleterious	3,61	23,2	0,16	0,55	disease	0,85	disease	0,82	disease	0,76	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,71	0,68	0,9	1,95	6,61	P	0,59	P	0,92	polymorphism	0,88	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6879	6879	A	T	MI.3965	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	976	326	T	S	Aca/Tca	-13,06	0	0	probably_damaging	0,98	deleterious	0,01	neutral	2,48	neutral	-2,84	deleterious	-2,59	medium_impact	2,81	neutral	0,67	damaging	0,06	deleterious	3,52	23,1	0,42	0,55	disease	0,52	disease	0,65	neutral	0,35	neutral	0,34	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,77	low_impact	-2,35	medium_impact	-0,92	medium_impact	1,5	0,76	0,9	1,95	6,61	N	0,24	N	0,79	polymorphism	0,99	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6879	6879	A	G	MI.3966	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	976	326	T	A	Aca/Gca	-13,06	0	0	probably_damaging	0,98	deleterious	0	neutral	2,45	deleterious	-3,46	deleterious	-3,24	high_impact	5,21	neutral	0,7	damaging	0,06	deleterious	3,6	23,2	0,42	0,55	disease	0,6	disease	0,7	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,35	low_impact	-1,48	high_impact	3,71	0,55	0,9	1,95	6,61	P	0,58	P	0,69	polymorphism	0,97	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6880	6880	C	A	MI.3967	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	977	326	T	K	aCa/aAa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,41	deleterious	-4,44	deleterious	-3,9	high_impact	5,21	neutral	0,62	damaging	0,04	deleterious	4,53	24,3	0,19	0,55	disease	0,79	disease	0,86	disease	0,74	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,71	0,63	0,9	1,95	6,61	P	0,75	P	0,88	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6880	6880	C	T	MI.3968	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	977	326	T	M	aCa/aTa	8,69	1	0	probably_damaging	1	neutral	0,06	neutral	2,47	neutral	-2,99	deleterious	-3,9	high_impact	3,74	neutral	0,67	damaging	0,04	deleterious	4,16	23,8	0,36	0,55	disease	0,85	disease	0,79	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,8	low_impact	-3,58	medium_impact	-0,47	high_impact	2,35	0,63	0,9	1,95	6,61	P	0,52	P	0,96	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6882	6882	C	A	MI.3969	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	979	327	L	I	Ctc/Atc	-9,82	0	0	probably_damaging	0,99	neutral	0,24	neutral	2,7	neutral	-1,57	neutral	-0,62	neutral_impact	0,75	damaging	0,59	damaging	0,24	deleterious	2,65	20,5	0,33	0,55	neutral	0,31	neutral	0,36	neutral	0,15	neutral	0,44	1	deleterious	0,99	neutral	0,13	neutral	-2	deleterious	0,68	low_impact	-2,64	medium_impact	-0,09	medium_impact	-0,41	0,72	0,9	1,95	6,8	N	0,47	N	0,54	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8711	8711	A	G	MI.397	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	185	62	N	S	aAc/aGc	1,29	0	0	benign	0,02	neutral	0,81	neutral	4,44	neutral	0,51	deleterious	-3,55	neutral_impact	0,71	neutral	0,9	neutral	0,94	neutral	-0,24	0,92	0,85	0,9	neutral	0,41	neutral	0,47	neutral	0,26	neutral	0,46	1	neutral	0,14	deleterious	0,9	neutral	-6	neutral	0,18	medium_impact	0,85	medium_impact	0,65	medium_impact	-0,49	0,4	0,9	18,14	14,91	N	0,3	N	0	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6882	6882	C	G	MI.3970	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	979	327	L	V	Ctc/Gtc	-9,82	0	0	probably_damaging	0,97	deleterious	0,02	neutral	2,72	neutral	-1,69	neutral	-1,21	medium_impact	2,94	damaging	0,56	damaging	0,14	deleterious	3,54	23,1	0,38	0,55	neutral	0,39	disease	0,57	neutral	0,24	neutral	0,37	3	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,69	low_impact	-2,18	medium_impact	-0,75	medium_impact	1,62	0,65	0,9	1,95	6,8	N	0,37	N	0,66	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6882	6882	C	T	MI.3971	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	979	327	L	F	Ctc/Ttc	-9,82	0	0	probably_damaging	1	neutral	0,08	neutral	2,6	neutral	-2,64	neutral	-1,89	low_impact	1,84	damaging	0,58	damaging	0,17	deleterious	4,03	23,6	0,36	0,55	disease	0,57	disease	0,63	neutral	0,22	neutral	0,26	5	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,76	low_impact	-3,58	medium_impact	-0,4	medium_impact	0,6	0,7	0,9	1,95	6,8	N	0,34	N	0,87	polymorphism	0,9	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6883	6883	T	C	MI.3972	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	980	327	L	P	cTc/cCc	0,13	0,01	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-4,98	deleterious	-4,01	high_impact	4,5	damaging	0,52	damaging	0,1	deleterious	4,07	23,7	0,13	0,55	disease	0,76	disease	0,89	disease	0,66	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,59	0,9	1,95	6,8	N	0,38	N	0,83	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6883	6883	T	A	MI.3973	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	980	327	L	H	cTc/cAc	0,13	0,01	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-4,94	deleterious	-3,86	high_impact	4,5	damaging	0,59	damaging	0,09	deleterious	4,42	24,2	0,15	0,55	disease	0,75	disease	0,78	disease	0,61	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,49	0,9	1,95	6,8	N	0,38	N	0,83	disease_causing	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6883	6883	T	G	MI.3974	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	980	327	L	R	cTc/cGc	0,13	0,01	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-4,41	deleterious	-3,5	high_impact	4,5	damaging	0,57	damaging	0,09	deleterious	4,31	24	0,13	0,55	disease	0,67	disease	0,88	disease	0,65	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,42	0,9	1,95	6,8	N	0,39	N	0,9	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6885	6885	C	G	MI.3975	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	982	328	H	D	Cac/Gac	-15,6	0	0	probably_damaging	1	deleterious	0,03	neutral	2,79	neutral	-1,2	deleterious	-4,1	high_impact	4,04	neutral	0,61	damaging	0,08	deleterious	3,98	23,6	0,29	0,55	disease	0,65	disease	0,86	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-3,58	medium_impact	-0,65	high_impact	2,63	0,52	0,9	1,75	6,76	N	0,29	N	0,97	polymorphism	0,89	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6885	6885	C	A	MI.3976	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	982	328	H	N	Cac/Aac	-15,6	0	0	probably_damaging	0,99	deleterious	0,04	neutral	2,83	neutral	-0,86	deleterious	-3,15	low_impact	1,7	neutral	0,6	damaging	0,1	deleterious	3,98	23,6	0,61	0,65	disease	0,52	disease	0,81	neutral	0,36	neutral	0,41	2	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,8	low_impact	-2,64	medium_impact	-0,58	medium_impact	0,47	0,47	0,9	1,75	6,76	N	0,27	N	0,86	polymorphism	0,97	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6885	6885	C	T	MI.3977	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	982	328	H	Y	Cac/Tac	-15,6	0	0	probably_damaging	0,99	neutral	0,45	neutral	2,89	neutral	0,86	neutral	-1,19	neutral_impact	0,06	neutral	0,66	neutral	0,31	deleterious	2,39	18,78	0,68	0,7	neutral	0,17	disease	0,59	neutral	0,21	neutral	0,34	3	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,73	low_impact	-2,64	medium_impact	0,14	low_impact	-1,04	0,29	0,9	1,75	6,76	N	0,32	N	0,72	polymorphism	0,96	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6886	6886	A	C	MI.3978	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	983	328	H	P	cAc/cCc	4,52	1	0	probably_damaging	1	deleterious	0,03	neutral	2,78	neutral	-2	deleterious	-4,54	high_impact	4,04	damaging	0,59	damaging	0,09	deleterious	3,34	22,9	0,28	0,55	disease	0,57	disease	0,93	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,88	low_impact	-3,58	medium_impact	-0,65	high_impact	2,63	0,31	0,9	1,75	6,76	N	0,44	N	0,9	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6886	6886	A	T	MI.3979	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	983	328	H	L	cAc/cTc	4,52	1	0	probably_damaging	0,99	neutral	0,16	neutral	2,91	neutral	0,19	deleterious	-4,5	low_impact	1,9	neutral	0,63	damaging	0,07	deleterious	3,94	23,5	0,33	0,55	neutral	0,27	disease	0,86	neutral	0,43	disease	0,57	1	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,74	low_impact	-2,64	medium_impact	-0,21	medium_impact	0,66	0,32	0,9	1,75	6,76	N	0,37	N	0,92	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8711	8711	A	C	MI.398	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	185	62	N	T	aAc/aCc	1,29	0	0	benign	0,19	neutral	0,34	neutral	4,35	neutral	-0,68	deleterious	-4,58	medium_impact	2,46	neutral	0,89	neutral	0,93	deleterious	0,39	6,48	0,82	0,85	neutral	0,28	disease	0,71	neutral	0,25	neutral	0,47	1	neutral	0,59	deleterious	0,58	neutral	-3	neutral	0,28	medium_impact	-0,16	medium_impact	0,13	medium_impact	1,01	0,66	0,9	18,14	14,91	N	0,44	N	0,06	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6886	6886	A	G	MI.3980	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	983	328	H	R	cAc/cGc	4,52	1	0	probably_damaging	0,99	neutral	0,05	neutral	2,87	neutral	-0,2	deleterious	-3,52	high_impact	4,04	neutral	0,61	damaging	0,07	deleterious	3,1	22,5	0,64	0,65	neutral	0,48	disease	0,83	disease	0,51	disease	0,66	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,82	low_impact	-2,64	medium_impact	-0,52	high_impact	2,63	0,32	0,9	1,75	6,76	N	0,46	N	0,85	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6887	6887	C	A	MI.3981	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	984	328	H	Q	caC/caA	8,69	1	0	probably_damaging	0,99	neutral	0,12	neutral	2,83	neutral	-0,7	deleterious	-3,14	low_impact	1,68	neutral	0,63	damaging	0,11	deleterious	2,84	21,5	0,66	0,7	disease	0,5	disease	0,72	neutral	0,32	neutral	0,37	3	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,79	low_impact	-2,64	medium_impact	-0,29	medium_impact	0,45	0,54	0,9	1,75	6,76	N	0,47	N	0,83	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6887	6887	C	G	MI.3982	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	984	328	H	Q	caC/caG	8,69	1	0	probably_damaging	0,99	neutral	0,12	neutral	2,83	neutral	-0,7	deleterious	-3,14	low_impact	1,68	neutral	0,63	damaging	0,11	deleterious	2,46	19,19	0,66	0,7	disease	0,5	disease	0,72	neutral	0,32	neutral	0,37	3	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,79	low_impact	-2,64	medium_impact	-0,29	medium_impact	0,45	0,54	0,9	1,75	6,76	N	0,46	N	0,83	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6888	6888	G	T	MI.3983	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	985	329	G	W	Gga/Tga	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-6,38	deleterious	-5,2	high_impact	4,83	neutral	0,62	damaging	0,09	deleterious	4,53	24,3	0,17	0,55	disease	0,88	disease	0,91	disease	0,67	disease	0,63	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,36	0,42	0,9	3,9	6,65	P	0,58	P	0,83	disease_causing	0,56	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6888	6888	G	C	MI.3984	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	985	329	G	R	Gga/Cga	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	2,68	neutral	-1,74	deleterious	-5,2	medium_impact	3,42	neutral	0,61	damaging	0,07	deleterious	4,06	23,7	0,2	0,55	neutral	0,31	disease	0,88	disease	0,63	disease	0,68	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,06	0,76	0,9	3,9	6,65	N	0,28	N	0,95	polymorphism	0,56	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6889	6889	G	C	MI.3985	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	986	329	G	A	gGa/gCa	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-3,38	deleterious	-3,9	high_impact	4,28	neutral	0,78	damaging	0,14	deleterious	3,2	22,7	0,27	0,55	neutral	0,21	disease	0,73	disease	0,56	disease	0,51	0	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	high_impact	2,85	0,65	0,9	3,9	6,65	N	0,44	N	0,64	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6889	6889	G	A	MI.3986	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	986	329	G	E	gGa/gAa	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-3,1	deleterious	-5,2	high_impact	4,28	damaging	0,5	damaging	0,12	deleterious	3,95	23,6	0,22	0,55	neutral	0,24	disease	0,88	disease	0,62	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,85	0,56	0,9	3,9	6,65	N	0,44	N	0,93	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6889	6889	G	T	MI.3987	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	986	329	G	V	gGa/gTa	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-4,23	deleterious	-5,85	high_impact	5,17	neutral	0,61	damaging	0,09	deleterious	3,81	23,4	0,17	0,55	neutral	0,42	disease	0,87	disease	0,6	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,49	0,9	3,9	6,65	P	0,61	P	0,93	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6891	6891	A	G	MI.3988	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	988	330	S	G	Agc/Ggc	-3,11	0	0	benign	0	neutral	1	neutral	3,15	neutral	1,75	neutral	-1,52	low_impact	1,46	neutral	0,75	neutral	0,99	neutral	-0,69	0,08	0,34	0,55	neutral	0,42	neutral	0,19	neutral	0,14	neutral	0,36	3	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,07	high_impact	1,86	medium_impact	0,25	0,81	0,9	7,21	28,88	N	0,44	N	0	polymorphism	1	0,04	rs879091068	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6891	6891	A	C	MI.3989	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	988	330	S	R	Agc/Cgc	-3,11	0	0	benign	0	deleterious	0,01	neutral	2,9	neutral	-1,12	neutral	-2,2	high_impact	3,51	neutral	0,61	neutral	0,59	deleterious	2,03	16,4	0,25	0,55	neutral	0,44	disease	0,84	neutral	0,48	disease	0,63	3	deleterious	0,99	deleterious	0,51	deleterious	2	neutral	0,24	high_impact	2,07	medium_impact	-0,92	high_impact	2,14	0,8	0,9	7,21	28,88	N	0,42	N	0,49	polymorphism	0,99	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8712	8712	C	A	MI.399	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	186	62	N	K	aaC/aaA	0,59	0	0	benign	0,28	neutral	0,41	neutral	4,45	neutral	0,61	deleterious	-4,78	low_impact	1,54	neutral	0,75	neutral	0,49	deleterious	2,46	19,2	0,89	0,9	neutral	0,35	disease	0,76	neutral	0,36	disease	0,52	0	neutral	0,5	deleterious	0,57	neutral	-6	neutral	0,39	medium_impact	-0,37	medium_impact	0,2	medium_impact	0,22	0,78	0,9	18,14	14,91	N	0,32	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6891	6891	A	T	MI.3990	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	988	330	S	C	Agc/Tgc	-3,11	0	0	benign	0,1	deleterious	0,04	neutral	2,81	deleterious	-4,12	neutral	-2,19	medium_impact	3,44	damaging	0,56	neutral	0,47	neutral	1,67	14,25	0,28	0,55	disease	0,65	disease	0,8	neutral	0,36	disease	0,62	2	neutral	0,96	deleterious	0,47	deleterious	1	neutral	0,37	medium_impact	0,14	medium_impact	-0,58	high_impact	2,08	0,74	0,9	7,21	28,88	N	0,4	N	0,55	polymorphism	0,99	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6892	6892	G	C	MI.3991	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	989	330	S	T	aGc/aCc	5,22	1	0	benign	0	neutral	0,34	neutral	2,87	neutral	-1,05	neutral	-0,48	low_impact	1,04	neutral	0,65	neutral	0,76	neutral	-0,43	0,33	0,32	0,55	neutral	0,28	neutral	0,25	neutral	0,15	neutral	0,44	1	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,13	high_impact	2,07	medium_impact	0,03	medium_impact	-0,14	0,78	0,9	7,21	28,88	P	0,67	P	0,32	polymorphism	0,66	0,04	.	.	.	.	.	.	COSM5656135	.	.	.	.	.	.	.	.
chrM	6892	6892	G	A	MI.3992	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	989	330	S	N	aGc/aAc	5,22	1	0	benign	0	deleterious	0,01	neutral	2,88	neutral	-1,15	neutral	-1,32	medium_impact	2,79	neutral	0,68	neutral	0,78	deleterious	0,7	8,83	0,55	0,6	neutral	0,44	disease	0,7	neutral	0,4	neutral	0,33	3	deleterious	0,99	deleterious	0,51	deleterious	1	neutral	0,19	high_impact	2,07	medium_impact	-0,92	medium_impact	1,48	0,64	0,9	7,21	28,88	P	0,57	P	0,23	polymorphism	0,61	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6892	6892	G	T	MI.3993	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	989	330	S	I	aGc/aTc	5,22	1	0	benign	0,02	deleterious	0,02	neutral	2,83	neutral	-2,31	neutral	-2,49	medium_impact	2,9	neutral	0,6	neutral	0,65	neutral	1,22	11,84	0,26	0,55	neutral	0,42	disease	0,86	neutral	0,37	neutral	0,45	1	neutral	0,98	deleterious	0,5	deleterious	1	neutral	0,23	medium_impact	0,83	medium_impact	-0,75	medium_impact	1,58	0,84	0,9	7,21	28,88	P	0,55	P	0,59	disease_causing	0,83	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6894	6894	A	T	MI.3994	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	991	331	N	Y	Aat/Tat	-12,6	0	0	probably_damaging	0,95	neutral	0,17	neutral	2,75	deleterious	-3,18	neutral	0,07	neutral_impact	-0,02	neutral	0,78	neutral	0,49	deleterious	2,05	16,56	0,41	0,55	disease	0,58	neutral	0,32	neutral	0,18	disease	0,6	2	neutral	0,97	neutral	0,11	neutral	-2	deleterious	0,67	low_impact	-1,96	medium_impact	-0,19	low_impact	-1,12	0,53	0,9	11,89	12,58	N	0,48	N	0,93	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6894	6894	A	C	MI.3995	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	991	331	N	H	Aat/Cat	-12,6	0	0	possibly_damaging	0,88	neutral	0,21	neutral	2,77	neutral	-1,96	neutral	0,06	neutral_impact	0,68	neutral	0,79	neutral	0,55	neutral	1,65	14,11	0,65	0,7	neutral	0,46	neutral	0,24	neutral	0,19	neutral	0,46	1	neutral	0,92	neutral	0,17	neutral	-3	deleterious	0,6	low_impact	-1,57	medium_impact	-0,13	medium_impact	-0,47	0,55	0,9	11,89	12,58	N	0,5	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6894	6894	A	G	MI.3996	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	991	331	N	D	Aat/Gat	-12,6	0	0	benign	0,01	neutral	0,3	neutral	2,8	neutral	-0,71	neutral	-0,63	low_impact	1,52	neutral	0,81	neutral	0,62	deleterious	0,79	9,39	0,76	0,8	neutral	0,27	neutral	0,34	neutral	0,27	neutral	0,45	1	neutral	0,69	deleterious	0,65	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	-0,01	medium_impact	0,3	0,61	0,9	11,89	12,58	N	0,47	N	0,92	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6895	6895	A	G	MI.3997	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	992	331	N	S	aAt/aGt	0,59	0	0	benign	0,1	neutral	0,82	neutral	2,86	neutral	0,41	neutral	-0,12	neutral_impact	-0,6	neutral	0,74	neutral	0,75	neutral	-0,48	0,25	0,71	0,75	neutral	0,2	neutral	0,11	neutral	0,11	neutral	0,24	5	neutral	0,08	deleterious	0,86	neutral	-6	neutral	0,14	medium_impact	0,14	medium_impact	0,56	low_impact	-1,65	0,33	0,9	11,89	12,58	N	0,39	N	0,79	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6895	6895	A	C	MI.3998	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	992	331	N	T	aAt/aCt	0,59	0	0	benign	0,4	neutral	0,51	neutral	2,8	neutral	-1,04	neutral	-0,52	neutral_impact	0,71	neutral	0,71	neutral	0,63	deleterious	0,16	4,3	0,5	0,55	neutral	0,28	neutral	0,2	neutral	0,25	neutral	0,36	3	neutral	0,43	deleterious	0,56	neutral	-6	neutral	0,34	medium_impact	-0,59	medium_impact	0,2	medium_impact	-0,44	0,56	0,9	11,89	12,58	N	0,39	N	0,59	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6895	6895	A	T	MI.3999	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	992	331	N	I	aAt/aTt	0,59	0	0	probably_damaging	0,92	neutral	0,25	neutral	2,75	neutral	-2,91	neutral	-1,4	low_impact	0,83	neutral	0,75	neutral	0,61	deleterious	2,59	20,1	0,38	0,55	disease	0,54	disease	0,5	neutral	0,27	neutral	0,29	4	neutral	0,94	neutral	0,17	neutral	-2	deleterious	0,67	low_impact	-1,76	medium_impact	-0,07	medium_impact	-0,33	0,49	0,9	11,89	12,58	N	0,38	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8528	8528	T	C	MI.4	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	2	1	M	T	aTg/aCg	5,68	1	0	possibly_damaging	0,8	deleterious	0	neutral	4,49	neutral	-0,97	deleterious	-4,97	NA	NA	neutral	0,7	damaging	0,13	deleterious	3,65	23,2	0,47	0,65	disease	0,58	neutral	0,5	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,1	deleterious	3	deleterious	0,76	NA	NA	NA	NA	NA	NA	0,24	0,9	50	8,74	P	0,63	P	0,97	NA	NA	0,31	rs387906422	Pathogenic	Cardiomyopathy,_infantile_hypertrophic	RCV000010272.6	MedGen:OMIM	.	.	.	.	T8528C	Infantile cardiomyopathy	+	+	Confirmed	3
chrM	8543	8543	T	G	MI.40	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	17	6	F	C	tTc/tGc	4,76	1	0	probably_damaging	0,99	deleterious	0	neutral	3,87	deleterious	-3,88	deleterious	-6,74	medium_impact	3,32	damaging	0,58	neutral	0,53	deleterious	4,06	23,7	0,31	0,65	disease	0,92	disease	0,72	disease	0,82	disease	0,87	7	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-2,65	low_impact	-1,4	medium_impact	1,75	0,19	0,9	39,82	8,43	P	0,58	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8712	8712	C	G	MI.400	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	186	62	N	K	aaC/aaG	0,59	0	0	benign	0,28	neutral	0,41	neutral	4,45	neutral	0,61	deleterious	-4,78	low_impact	1,54	neutral	0,75	neutral	0,49	deleterious	2,01	16,29	0,89	0,9	neutral	0,35	disease	0,76	neutral	0,36	disease	0,52	0	neutral	0,5	deleterious	0,57	neutral	-6	neutral	0,39	medium_impact	-0,37	medium_impact	0,2	medium_impact	0,22	0,78	0,9	18,14	14,91	N	0,32	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6896	6896	T	G	MI.4000	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	993	331	N	K	aaT/aaG	1,98	0	0	possibly_damaging	0,54	neutral	1	neutral	2,96	neutral	0,15	neutral	0,88	neutral_impact	-1,42	neutral	0,73	neutral	0,54	neutral	-0,08	1,92	0,73	0,75	neutral	0,18	neutral	0,13	neutral	0,14	neutral	0,24	5	neutral	0,54	deleterious	0,73	neutral	-3	deleterious	0,47	medium_impact	-0,82	high_impact	1,86	low_impact	-2,41	0,71	0,9	11,89	12,58	N	0,35	N	0,92	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6896	6896	T	A	MI.4001	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	993	331	N	K	aaT/aaA	1,98	0	0	possibly_damaging	0,54	neutral	1	neutral	2,96	neutral	0,15	neutral	0,88	neutral_impact	-1,42	neutral	0,73	neutral	0,54	deleterious	0,25	5,15	0,73	0,75	neutral	0,18	neutral	0,13	neutral	0,14	neutral	0,24	5	neutral	0,54	deleterious	0,73	neutral	-3	deleterious	0,47	medium_impact	-0,82	high_impact	1,86	low_impact	-2,41	0,71	0,9	11,89	12,58	N	0,36	N	0,92	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6897	6897	A	C	MI.4002	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	994	332	M	L	Atg/Ctg	-6,12	0	0	benign	0	neutral	0,46	neutral	3,05	neutral	2,33	neutral	0,31	neutral_impact	-1,73	neutral	0,66	neutral	0,81	neutral	-0,39	0,41	0,48	0,55	neutral	0,26	neutral	0,33	neutral	0,22	neutral	0,44	1	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,15	low_impact	-2,7	0,55	0,9	7,99	24,73	N	0,44	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6897	6897	A	G	MI.4003	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	994	332	M	V	Atg/Gtg	-6,12	0	0	benign	0	neutral	0,21	neutral	2,9	neutral	1,27	neutral	0	neutral_impact	-0,78	neutral	0,75	neutral	0,86	neutral	-0,46	0,27	0,49	0,55	neutral	0,26	neutral	0,42	neutral	0,23	neutral	0,44	1	neutral	0,79	deleterious	0,61	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	-0,13	low_impact	-1,82	0,42	0,9	7,99	24,73	N	0,47	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6897	6897	A	T	MI.4004	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	994	332	M	L	Atg/Ttg	-6,12	0	0	benign	0	neutral	0,46	neutral	3,05	neutral	2,33	neutral	0,31	neutral_impact	-1,73	neutral	0,66	neutral	0,81	neutral	-0,38	0,44	0,48	0,55	neutral	0,26	neutral	0,33	neutral	0,22	neutral	0,44	1	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,15	low_impact	-2,7	0,55	0,9	7,99	24,73	N	0,45	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6898	6898	T	C	MI.4005	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	995	332	M	T	aTg/aCg	4,76	0,99	0	benign	0	neutral	0,09	neutral	2,82	neutral	-0,4	neutral	-1,54	low_impact	0,95	neutral	0,7	neutral	0,91	neutral	1,08	11,1	0,38	0,55	neutral	0,27	disease	0,52	neutral	0,42	neutral	0,22	6	neutral	0,91	deleterious	0,55	neutral	-6	neutral	0,16	high_impact	2,07	medium_impact	-0,37	medium_impact	-0,22	0,18	0,9	7,99	24,73	P	0,61	P	0	polymorphism	0,62	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6898	6898	T	A	MI.4006	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	995	332	M	K	aTg/aAg	4,76	0,99	0	benign	0	deleterious	0,01	neutral	2,77	neutral	-1,65	neutral	-2,4	neutral_impact	0,68	damaging	0,58	neutral	0,51	deleterious	2,09	16,76	0,23	0,55	neutral	0,45	disease	0,71	neutral	0,45	neutral	0,35	3	deleterious	0,99	deleterious	0,51	neutral	-2	neutral	0,23	high_impact	2,07	medium_impact	-0,92	medium_impact	-0,47	0,49	0,9	7,99	24,73	P	0,5	N	0,32	disease_causing	0,82	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6899	6899	G	C	MI.4007	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	996	332	M	I	atG/atC	3,83	1	0,01	benign	0	neutral	1	neutral	3	neutral	2,13	neutral	0,49	neutral_impact	-1,9	neutral	0,77	neutral	1	neutral	-0,93	0,02	0,58	0,65	neutral	0,32	neutral	0,18	neutral	0,15	neutral	0,27	5	neutral	0	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,07	high_impact	1,86	low_impact	-2,85	0,52	0,9	7,99	24,73	N	0,46	N	0	polymorphism	0,97	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6899	6899	G	T	MI.4008	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	996	332	M	I	atG/atT	3,83	1	0,01	benign	0	neutral	1	neutral	3	neutral	2,13	neutral	0,49	neutral_impact	-1,9	neutral	0,77	neutral	1	neutral	-0,83	0,04	0,58	0,65	neutral	0,32	neutral	0,18	neutral	0,15	neutral	0,27	5	neutral	0	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,07	high_impact	1,86	low_impact	-2,85	0,52	0,9	7,99	24,73	N	0,45	N	0	polymorphism	0,97	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6900	6900	A	C	MI.4009	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	997	333	K	Q	Aaa/Caa	-4,27	0	0	benign	0,08	neutral	0,05	neutral	2,89	neutral	-0,55	neutral	-0,66	low_impact	1,83	neutral	0,69	damaging	0,21	deleterious	0,38	6,44	0,51	0,6	neutral	0,28	disease	0,58	neutral	0,23	neutral	0,21	6	neutral	0,95	deleterious	0,49	neutral	-6	neutral	0,27	medium_impact	0,24	medium_impact	-0,52	medium_impact	0,59	0,7	0,9	11,11	8,78	N	0,44	N	0,64	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8713	8713	A	T	MI.401	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	187	63	T	S	Act/Tct	-2,42	0	0	benign	0,07	neutral	0,76	neutral	3,98	neutral	1,07	neutral	-1,04	neutral_impact	0,16	neutral	0,87	neutral	0,82	neutral	-0,88	0,03	0,67	0,75	neutral	0,33	neutral	0,22	neutral	0,14	neutral	0,42	2	neutral	0,15	deleterious	0,85	neutral	-6	neutral	0,12	medium_impact	0,31	medium_impact	0,57	medium_impact	-0,96	0,8	0,9	18,58	14,48	N	0,39	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6900	6900	A	G	MI.4010	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	997	333	K	E	Aaa/Gaa	-4,27	0	0	benign	0,06	deleterious	0,02	neutral	2,9	neutral	-0,41	neutral	-0,74	medium_impact	1,97	neutral	0,63	damaging	0,18	neutral	1,07	11,06	0,39	0,55	neutral	0,29	disease	0,75	neutral	0,28	neutral	0,23	5	neutral	0,98	deleterious	0,48	deleterious	1	neutral	0,28	medium_impact	0,37	medium_impact	-0,75	medium_impact	0,72	0,63	0,9	11,11	8,78	N	0,39	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6901	6901	A	C	MI.4011	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	998	333	K	T	aAa/aCa	7,07	1	0	benign	0	neutral	0,09	neutral	2,94	neutral	-0,78	neutral	-0,85	low_impact	1,29	neutral	0,67	damaging	0,22	deleterious	0,46	7,1	0,29	0,55	neutral	0,41	neutral	0,47	neutral	0,34	neutral	0,34	3	neutral	0,91	deleterious	0,55	neutral	-6	neutral	0,18	high_impact	2,07	medium_impact	-0,37	medium_impact	0,09	0,58	0,9	11,11	8,78	P	0,61	P	0,76	disease_causing	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6901	6901	A	T	MI.4012	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	998	333	K	M	aAa/aTa	7,07	1	0	possibly_damaging	0,52	deleterious	0,04	neutral	2,88	deleterious	-3,52	neutral	-1,5	medium_impact	2,44	neutral	0,68	damaging	0,16	deleterious	2,43	19,04	0,34	0,55	disease	0,66	disease	0,56	neutral	0,26	neutral	0,25	5	neutral	0,96	neutral	0,26	deleterious	4	deleterious	0,5	medium_impact	-0,79	medium_impact	-0,58	medium_impact	1,15	0,57	0,9	11,11	8,78	P	0,49	N	0,89	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6902	6902	A	C	MI.4013	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	999	333	K	N	aaA/aaC	5,68	1	0	benign	0,14	neutral	0,39	neutral	2,91	neutral	-1,25	neutral	0,18	neutral_impact	0,34	neutral	0,66	neutral	0,39	deleterious	0,31	5,78	0,64	0,65	neutral	0,42	neutral	0,4	neutral	0,24	neutral	0,46	1	neutral	0,54	deleterious	0,63	neutral	-6	neutral	0,41	medium_impact	-0,01	medium_impact	0,09	medium_impact	-0,79	0,87	0,9	11,11	8,78	P	0,56	P	0,76	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6902	6902	A	T	MI.4014	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	999	333	K	N	aaA/aaT	5,68	1	0	benign	0,14	neutral	0,39	neutral	2,91	neutral	-1,25	neutral	0,18	neutral_impact	0,34	neutral	0,66	neutral	0,39	deleterious	0,31	5,79	0,64	0,65	neutral	0,42	neutral	0,4	neutral	0,24	neutral	0,46	1	neutral	0,54	deleterious	0,63	neutral	-6	neutral	0,41	medium_impact	-0,01	medium_impact	0,09	medium_impact	-0,79	0,87	0,9	11,11	8,78	P	0,55	P	0,76	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6903	6903	T	G	MI.4015	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1000	334	W	G	Tga/Gga	1,29	1	0	probably_damaging	0,99	deleterious	0,01	neutral	2,75	deleterious	-3,24	deleterious	-3,13	low_impact	1,68	damaging	0,56	damaging	0,06	deleterious	4,01	23,6	0,35	0,55	neutral	0,46	disease	0,59	disease	0,6	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	2	deleterious	0,74	low_impact	-2,64	medium_impact	-0,92	medium_impact	0,45	0,41	0,9	2,34	6,98	N	0,3	N	0,89	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6903	6903	T	C	MI.4016	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1000	334	W	R	Tga/Cga	1,29	1	0	probably_damaging	1	neutral	0,14	neutral	2,76	deleterious	-3,11	deleterious	-2,79	low_impact	1,62	damaging	0,51	damaging	0,04	deleterious	3,69	23,3	0,47	0,55	neutral	0,29	disease	0,73	disease	0,61	disease	0,7	4	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,75	low_impact	-3,58	medium_impact	-0,25	medium_impact	0,4	0,35	0,9	2,34	6,98	N	0,31	N	0,98	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6904	6904	G	C	MI.4017	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1001	334	W	S	tGa/tCa	5,91	1	0	probably_damaging	1	neutral	0,05	neutral	2,78	neutral	-2,18	deleterious	-2,5	low_impact	1,22	damaging	0,52	damaging	0,06	deleterious	3,01	22,3	0,31	0,55	neutral	0,31	disease	0,6	disease	0,56	neutral	0,33	3	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,73	low_impact	-3,58	medium_impact	-0,52	medium_impact	0,03	0,44	0,9	2,34	6,98	N	0,43	N	0,89	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6904	6904	G	T	MI.4018	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1001	334	W	L	tGa/tTa	5,91	1	0	probably_damaging	0,99	neutral	0,16	neutral	2,89	neutral	0,29	neutral	-1,34	neutral_impact	-0,86	damaging	0,54	damaging	0,04	deleterious	3,06	22,4	0,3	0,55	neutral	0,22	neutral	0,4	neutral	0,3	neutral	0,43	1	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,68	low_impact	-2,64	medium_impact	-0,21	low_impact	-1,89	0,26	0,9	2,34	6,98	N	0,51	P	0,95	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6905	6905	A	T	MI.4019	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1002	334	W	C	tgA/tgT	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,72	deleterious	-3,57	neutral	-2,42	medium_impact	2,31	damaging	0,52	damaging	0,04	deleterious	4,21	23,9	0,39	0,55	disease	0,5	disease	0,77	disease	0,66	disease	0,73	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	medium_impact	1,03	0,33	0,9	2,34	6,98	N	0,42	N	0,88	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8713	8713	A	G	MI.402	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	187	63	T	A	Act/Gct	-2,42	0	0	benign	0	neutral	0,75	neutral	3,92	neutral	0,25	neutral	-1,01	neutral_impact	0,64	neutral	0,97	neutral	0,96	neutral	-0,96	0,02	0,63	0,7	neutral	0,28	neutral	0,26	neutral	0,27	neutral	0,42	2	neutral	0,24	deleterious	0,88	neutral	-6	neutral	0,09	high_impact	2,09	medium_impact	0,56	medium_impact	-0,55	0,36	0,9	18,58	14,48	N	0,34	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6905	6905	A	C	MI.4020	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1002	334	W	C	tgA/tgC	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,72	deleterious	-3,57	neutral	-2,42	medium_impact	2,31	damaging	0,52	damaging	0,04	deleterious	4,16	23,8	0,39	0,55	disease	0,5	disease	0,77	disease	0,66	disease	0,73	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	medium_impact	1,03	0,33	0,9	2,34	6,98	N	0,42	N	0,88	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6906	6906	T	A	MI.4021	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1003	335	S	T	Tct/Act	2,21	1	0	benign	0,15	neutral	0,14	neutral	2,93	neutral	-0,67	neutral	-1	neutral_impact	0,72	neutral	0,69	damaging	0,25	deleterious	0,78	9,32	0,53	0,6	neutral	0,16	neutral	0,38	neutral	0,14	neutral	0,45	1	neutral	0,84	deleterious	0,5	neutral	-6	neutral	0,16	medium_impact	-0,05	medium_impact	-0,25	medium_impact	-0,43	0,83	0,9	10,92	10,49	P	0,51	P	0,43	polymorphism	0,7	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6906	6906	T	C	MI.4022	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1003	335	S	P	Tct/Cct	2,21	1	0	possibly_damaging	0,73	deleterious	0,02	neutral	2,83	neutral	-2,52	neutral	-2,01	medium_impact	2,77	damaging	0,51	damaging	0,09	deleterious	3,86	23,5	0,32	0,55	disease	0,53	disease	0,9	neutral	0,32	disease	0,52	0	deleterious	0,98	neutral	0,15	deleterious	4	deleterious	0,65	low_impact	-1,16	medium_impact	-0,75	medium_impact	1,46	0,71	0,9	10,92	10,49	N	0,4	N	0,91	disease_causing	0,73	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6906	6906	T	G	MI.4023	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1003	335	S	A	Tct/Gct	2,21	1	0	benign	0,01	deleterious	0,03	neutral	2,85	neutral	-1,91	neutral	-1,55	medium_impact	2,57	neutral	0,71	neutral	0,57	deleterious	0,8	9,45	0,53	0,6	neutral	0,27	disease	0,58	neutral	0,28	neutral	0,4	2	neutral	0,97	deleterious	0,51	deleterious	1	neutral	0,17	medium_impact	1,12	medium_impact	-0,65	medium_impact	1,27	0,68	0,9	10,92	10,49	P	0,55	P	0,35	polymorphism	0,89	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6907	6907	C	G	MI.4024	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1004	335	S	C	tCt/tGt	2,9	1	0	probably_damaging	0,92	deleterious	0	neutral	2,8	deleterious	-5,28	deleterious	-2,65	high_impact	3,81	damaging	0,57	damaging	0,11	deleterious	3,57	23,2	0,38	0,55	disease	0,79	disease	0,84	neutral	0,22	disease	0,68	4	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,73	low_impact	-1,76	low_impact	-1,48	high_impact	2,42	0,82	0,9	10,92	10,49	N	0,38	N	0,85	polymorphism	0,88	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6907	6907	C	T	MI.4025	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1004	335	S	F	tCt/tTt	2,9	1	0	probably_damaging	0,96	deleterious	0	neutral	2,8	deleterious	-4,38	deleterious	-2,86	high_impact	3,81	damaging	0,6	damaging	0,09	deleterious	4,15	23,8	0,37	0,55	disease	0,67	disease	0,86	neutral	0,21	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,79	low_impact	-2,06	low_impact	-1,48	high_impact	2,42	0,38	0,9	10,92	10,49	N	0,38	N	0,98	polymorphism	0,71	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6907	6907	C	A	MI.4026	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1004	335	S	Y	tCt/tAt	2,9	1	0	probably_damaging	0,96	deleterious	0,01	neutral	2,81	deleterious	-3,58	deleterious	-2,63	medium_impact	3,19	neutral	0,63	damaging	0,1	deleterious	4,13	23,8	0,36	0,55	disease	0,61	disease	0,86	neutral	0,19	disease	0,54	1	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,78	low_impact	-2,06	medium_impact	-0,92	medium_impact	1,85	0,72	0,9	10,92	10,49	N	0,4	N	0,92	polymorphism	0,81	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6909	6909	G	T	MI.4027	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1006	336	A	S	Gct/Tct	-5,42	0	0	benign	0,13	deleterious	0,03	neutral	2,93	neutral	-0,96	neutral	0,01	neutral_impact	0,2	neutral	0,75	neutral	0,71	deleterious	1,92	15,69	0,38	0,55	neutral	0,19	disease	0,51	neutral	0,09	neutral	0,27	5	neutral	0,97	neutral	0,45	neutral	-2	neutral	0,21	medium_impact	0,02	medium_impact	-0,65	medium_impact	-0,91	0,74	0,9	10,14	27,75	N	0,56	P	0,39	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6909	6909	G	A	MI.4028	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1006	336	A	T	Gct/Act	-5,42	0	0	benign	0,18	neutral	0,74	neutral	3	neutral	0,05	neutral	0,39	neutral_impact	-0,55	neutral	0,64	neutral	0,72	neutral	0,91	10,12	0,3	0,55	neutral	0,18	neutral	0,23	neutral	0,1	neutral	0,42	2	neutral	0,15	deleterious	0,78	neutral	-6	neutral	0,2	medium_impact	-0,14	medium_impact	0,45	low_impact	-1,61	0,56	0,9	10,14	27,75	N	0,37	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6909	6909	G	C	MI.4029	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1006	336	A	P	Gct/Cct	-5,42	0	0	benign	0	neutral	1	neutral	3,17	neutral	1,18	neutral	1,93	neutral_impact	-1,57	neutral	0,74	neutral	0,97	neutral	-0,68	0,08	0,16	0,55	neutral	0,25	neutral	0,27	neutral	0,11	neutral	0,42	2	neutral	0	deleterious	1	neutral	-6	neutral	0,17	high_impact	2,07	high_impact	1,86	low_impact	-2,55	0,68	0,9	10,14	27,75	N	0,38	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8713	8713	A	C	MI.403	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	187	63	T	P	Act/Cct	-2,42	0	0	benign	0	neutral	0,77	neutral	3,92	neutral	0,23	neutral	-1,3	neutral_impact	-0,55	neutral	0,94	neutral	0,99	neutral	-0,94	0,02	0,33	0,65	neutral	0,31	neutral	0,46	neutral	0,11	neutral	0,44	1	neutral	0,22	deleterious	0,89	neutral	-6	neutral	0,14	high_impact	2,09	medium_impact	0,59	low_impact	-1,57	0,64	0,9	18,58	14,48	N	0,37	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6910	6910	C	T	MI.4030	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1007	336	A	V	gCt/gTt	2,44	0,98	0	benign	0,23	neutral	0,08	neutral	2,98	neutral	-0,17	neutral	-0,68	neutral_impact	0,02	neutral	0,76	neutral	0,68	neutral	1,76	14,74	0,19	0,55	neutral	0,23	disease	0,54	neutral	0,13	neutral	0,23	5	neutral	0,91	neutral	0,43	neutral	-6	neutral	0,23	medium_impact	-0,26	medium_impact	-0,4	low_impact	-1,08	0,63	0,9	10,14	27,75	P	0,54	P	0,63	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6910	6910	C	G	MI.4031	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1007	336	A	G	gCt/gGt	2,44	0,98	0	benign	0,18	deleterious	0	neutral	2,89	neutral	-2,19	neutral	-1,09	low_impact	1,72	neutral	0,68	neutral	0,57	deleterious	2,33	18,39	0,22	0,55	neutral	0,46	disease	0,59	neutral	0,21	neutral	0,45	1	deleterious	1	neutral	0,41	neutral	-2	neutral	0,27	medium_impact	-0,14	low_impact	-1,48	medium_impact	0,49	0,66	0,9	10,14	27,75	P	0,52	P	0,44	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6910	6910	C	A	MI.4032	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1007	336	A	D	gCt/gAt	2,44	0,98	0	benign	0,33	neutral	0,14	neutral	2,87	neutral	-2,95	neutral	-0,78	low_impact	1,82	neutral	0,65	neutral	0,45	deleterious	2,92	21,9	0,19	0,55	neutral	0,41	disease	0,86	neutral	0,39	disease	0,69	4	neutral	0,83	neutral	0,41	neutral	-6	neutral	0,38	medium_impact	-0,47	medium_impact	-0,25	medium_impact	0,58	0,49	0,9	10,14	27,75	N	0,51	P	0,48	polymorphism	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6912	6912	G	A	MI.4033	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1009	337	A	T	Gca/Aca	-16,07	0	0	probably_damaging	1	neutral	0,11	neutral	2,7	neutral	-1,48	neutral	-0,37	low_impact	1,03	neutral	0,68	damaging	0,17	deleterious	3,21	22,7	0,43	0,55	neutral	0,33	disease	0,52	neutral	0,22	neutral	0,28	4	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,72	low_impact	-3,58	medium_impact	-0,31	medium_impact	-0,15	0,72	0,9	4,87	10,37	N	0,41	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6912	6912	G	C	MI.4034	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1009	337	A	P	Gca/Cca	-16,07	0	0	probably_damaging	1	neutral	1	neutral	2,84	neutral	0,8	neutral	0,84	neutral_impact	-1,01	neutral	0,66	neutral	0,4	neutral	1,24	11,95	0,18	0,55	neutral	0,23	neutral	0,38	neutral	0,34	neutral	0,43	2	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,7	low_impact	-3,58	high_impact	1,86	low_impact	-2,03	0,78	0,9	4,87	10,37	N	0,27	N	0,85	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6912	6912	G	T	MI.4035	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1009	337	A	S	Gca/Tca	-16,07	0	0	probably_damaging	1	neutral	0,32	neutral	2,67	neutral	-1,28	neutral	0,36	neutral_impact	-0,87	neutral	0,65	damaging	0,24	neutral	1,69	14,33	0,44	0,55	neutral	0,24	neutral	0,2	neutral	0,24	neutral	0,35	3	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,68	low_impact	-3,58	medium_impact	0,01	low_impact	-1,9	0,81	0,9	4,87	10,37	N	0,38	N	0,64	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6913	6913	C	T	MI.4036	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1010	337	A	V	gCa/gTa	4,06	1	0	probably_damaging	1	neutral	0,06	neutral	2,73	neutral	-1,87	neutral	-1,41	medium_impact	1,99	neutral	0,66	damaging	0,16	deleterious	4,47	24,2	0,37	0,55	neutral	0,41	disease	0,68	neutral	0,3	neutral	0,25	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,74	low_impact	-3,58	medium_impact	-0,47	medium_impact	0,74	0,75	0,9	4,87	10,37	P	0,52	P	0,75	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6913	6913	C	A	MI.4037	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1010	337	A	E	gCa/gAa	4,06	1	0	probably_damaging	1	deleterious	0,04	neutral	2,69	neutral	-1,21	neutral	-0,87	medium_impact	1,95	damaging	0,59	damaging	0,13	deleterious	4,47	24,2	0,21	0,55	neutral	0,16	disease	0,85	disease	0,6	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,73	low_impact	-3,58	medium_impact	-0,58	medium_impact	0,7	0,64	0,9	4,87	10,37	N	0,4	N	0,76	disease_causing	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6913	6913	C	G	MI.4038	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1010	337	A	G	gCa/gGa	4,06	1	0	probably_damaging	1	deleterious	0,01	neutral	2,61	neutral	-1,96	neutral	-1,05	medium_impact	2,72	neutral	0,65	damaging	0,15	deleterious	4,02	23,6	0,31	0,55	neutral	0,45	disease	0,65	disease	0,52	disease	0,58	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,74	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,41	0,66	0,9	4,87	10,37	N	0,46	N	0,56	disease_causing	0,98	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6915	6915	G	A	MI.4039	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1012	338	V	M	Gtg/Atg	-15,6	0	0	benign	0	neutral	1	neutral	2,86	neutral	1,96	neutral	1,04	neutral_impact	-1,96	neutral	0,76	neutral	0,99	neutral	-0,91	0,03	0,4	0,55	neutral	0,28	neutral	0,12	neutral	0,14	neutral	0,29	4	neutral	0	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,07	high_impact	1,86	low_impact	-2,91	0,97	1	10,33	30,3	N	0,42	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8714	8714	C	A	MI.404	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	188	63	T	N	aCt/aAt	-4,5	0	0	benign	0,28	neutral	0,58	neutral	3,96	neutral	0,89	neutral	-1,81	neutral_impact	0,73	neutral	0,9	neutral	0,86	deleterious	-0,06	2,08	0,71	0,75	neutral	0,42	neutral	0,42	neutral	0,25	neutral	0,46	1	neutral	0,32	deleterious	0,65	neutral	-6	neutral	0,25	medium_impact	-0,37	medium_impact	0,37	medium_impact	-0,47	0,78	0,9	18,58	14,48	N	0,32	N	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6915	6915	G	C	MI.4040	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1012	338	V	L	Gtg/Ctg	-15,6	0	0	benign	0	neutral	0,92	neutral	2,89	neutral	1,1	neutral	0,86	neutral_impact	-1,56	neutral	0,76	neutral	0,97	neutral	-0,7	0,07	0,36	0,55	neutral	0,16	neutral	0,39	neutral	0,19	neutral	0,44	1	neutral	0,07	deleterious	0,96	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	0,78	low_impact	-2,54	0,66	0,9	10,33	30,3	N	0,35	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6915	6915	G	T	MI.4041	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1012	338	V	L	Gtg/Ttg	-15,6	0	0	benign	0	neutral	0,92	neutral	2,89	neutral	1,1	neutral	0,86	neutral_impact	-1,56	neutral	0,76	neutral	0,97	neutral	-0,6	0,13	0,36	0,55	neutral	0,16	neutral	0,39	neutral	0,19	neutral	0,44	1	neutral	0,07	deleterious	0,96	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	0,78	low_impact	-2,54	0,66	0,9	10,33	30,3	N	0,35	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6916	6916	T	C	MI.4042	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1013	338	V	A	gTg/gCg	0,82	0,23	0	benign	0,02	neutral	0,06	neutral	2,74	neutral	-0,27	neutral	-1,23	neutral_impact	0,78	neutral	0,67	neutral	0,75	neutral	1,71	14,45	0,36	0,55	neutral	0,25	disease	0,52	neutral	0,33	neutral	0,42	2	neutral	0,94	deleterious	0,52	neutral	-6	neutral	0,18	medium_impact	0,83	medium_impact	-0,47	medium_impact	-0,38	0,68	0,9	10,33	30,3	N	0,45	N	0,1	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6916	6916	T	A	MI.4043	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1013	338	V	E	gTg/gAg	0,82	0,23	0	benign	0,06	deleterious	0,01	neutral	2,65	neutral	-2,01	neutral	-2,2	low_impact	1,6	neutral	0,63	neutral	0,56	deleterious	2,96	22,1	0,16	0,55	neutral	0,25	disease	0,87	disease	0,61	disease	0,75	5	deleterious	0,99	deleterious	0,48	neutral	-2	neutral	0,25	medium_impact	0,37	medium_impact	-0,92	medium_impact	0,38	0,61	0,9	10,33	30,3	N	0,34	N	0,27	polymorphism	0,71	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6916	6916	T	G	MI.4044	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1013	338	V	G	gTg/gGg	0,82	0,23	0	benign	0,04	deleterious	0,01	neutral	2,69	neutral	-2,14	deleterious	-2,82	low_impact	1,72	neutral	0,65	neutral	0,51	deleterious	1,98	16,08	0,2	0,55	neutral	0,17	disease	0,7	neutral	0,47	neutral	0,48	0	deleterious	0,99	deleterious	0,49	neutral	-2	neutral	0,18	medium_impact	0,54	medium_impact	-0,92	medium_impact	0,49	0,59	0,9	10,33	30,3	N	0,38	N	0,3	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6918	6918	C	A	MI.4045	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1015	339	L	I	Ctc/Atc	-1,03	0	0	benign	0,34	neutral	0,08	neutral	2,5	neutral	-2,4	neutral	-0,94	low_impact	1,9	damaging	0,52	neutral	0,59	deleterious	2,42	18,94	0,33	0,55	neutral	0,49	disease	0,75	neutral	0,41	neutral	0,21	6	neutral	0,91	neutral	0,37	neutral	-6	neutral	0,41	medium_impact	-0,49	medium_impact	-0,4	medium_impact	0,66	0,81	0,9	3,9	51,21	N	0,46	N	0,21	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6918	6918	C	G	MI.4046	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1015	339	L	V	Ctc/Gtc	-1,03	0	0	benign	0,34	deleterious	0	neutral	2,51	neutral	-2,38	neutral	-1,41	medium_impact	3	damaging	0,52	neutral	0,49	neutral	1,77	14,81	0,35	0,55	neutral	0,45	disease	0,72	neutral	0,45	neutral	0,21	6	deleterious	1	neutral	0,33	deleterious	1	neutral	0,37	medium_impact	-0,49	low_impact	-1,48	medium_impact	1,67	0,81	0,9	3,9	51,21	N	0,42	N	0,49	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6918	6918	C	T	MI.4047	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1015	339	L	F	Ctc/Ttc	-1,03	0	0	benign	0,04	deleterious	0	neutral	2,49	deleterious	-3,35	neutral	-1,82	medium_impact	2,89	damaging	0,42	neutral	0,58	deleterious	2,07	16,64	0,38	0,55	disease	0,63	disease	0,85	disease	0,58	disease	0,57	1	deleterious	1	deleterious	0,48	deleterious	1	neutral	0,28	medium_impact	0,54	low_impact	-1,48	medium_impact	1,57	0,77	0,9	3,9	51,21	N	0,51	P	0,82	polymorphism	0,96	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6919	6919	T	G	MI.4048	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1016	339	L	R	cTc/cGc	-1,26	0	0	possibly_damaging	0,86	deleterious	0	neutral	2,52	deleterious	-4,47	deleterious	-3,16	high_impact	4,49	damaging	0,56	neutral	0,35	deleterious	4,18	23,8	0,09	0,55	disease	0,75	disease	0,95	disease	0,76	disease	0,83	7	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,81	low_impact	-1,5	low_impact	-1,48	high_impact	3,05	0,75	0,9	3,9	51,21	N	0,52	P	0,91	polymorphism	0,89	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6919	6919	T	C	MI.4049	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1016	339	L	P	cTc/cCc	-1,26	0	0	probably_damaging	0,93	deleterious	0	neutral	2,45	neutral	-2,35	deleterious	-3,76	high_impact	4,49	damaging	0,48	neutral	0,4	deleterious	3,92	23,5	0,11	0,55	disease	0,81	disease	0,93	disease	0,76	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,86	low_impact	-1,81	low_impact	-1,48	high_impact	3,05	0,66	0,9	3,9	51,21	P	0,56	P	0,81	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8714	8714	C	G	MI.405	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	188	63	T	S	aCt/aGt	-4,5	0	0	benign	0,07	neutral	0,76	neutral	3,98	neutral	1,07	neutral	-1,04	neutral_impact	0,16	neutral	0,87	neutral	0,82	neutral	-0,49	0,24	0,67	0,75	neutral	0,33	neutral	0,22	neutral	0,14	neutral	0,42	2	neutral	0,15	deleterious	0,85	neutral	-6	neutral	0,12	medium_impact	0,31	medium_impact	0,57	medium_impact	-0,96	0,8	0,9	18,58	14,48	N	0,36	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6919	6919	T	A	MI.4050	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1016	339	L	H	cTc/cAc	-1,26	0	0	probably_damaging	0,95	deleterious	0	neutral	2,45	deleterious	-4,84	deleterious	-3,59	high_impact	4,13	damaging	0,57	neutral	0,42	deleterious	4,2	23,9	0,14	0,55	disease	0,81	disease	0,89	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,81	low_impact	-1,96	low_impact	-1,48	high_impact	2,71	0,65	0,9	3,9	51,21	N	0,35	N	0,7	polymorphism	0,94	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6921	6921	T	C	MI.4051	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1018	340	W	R	Tga/Cga	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,74	deleterious	-3,63	deleterious	-8,77	high_impact	5,14	damaging	0,57	damaging	0,08	deleterious	3,65	23,2	0,22	0,55	disease	0,85	disease	0,96	disease	0,83	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,65	0,33	0,9	3,51	6,73	P	0,61	P	0,98	disease_causing	0,96	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6921	6921	T	G	MI.4052	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1018	340	W	G	Tga/Gga	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,75	deleterious	-3,23	deleterious	-8,14	high_impact	5,14	damaging	0,52	damaging	0,11	deleterious	3,97	23,6	0,19	0,55	disease	0,86	disease	0,92	disease	0,79	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,65	0,31	0,9	3,51	6,73	P	0,6	P	0,89	disease_causing	0,98	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6922	6922	G	C	MI.4053	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1019	340	W	S	tGa/tCa	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,77	neutral	-2,56	deleterious	-8,76	high_impact	4,45	neutral	0,66	damaging	0,1	deleterious	4,1	23,7	0,21	0,55	disease	0,78	disease	0,94	disease	0,77	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,01	0,28	0,9	3,51	6,73	P	0,56	P	0,89	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6922	6922	G	T	MI.4054	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1019	340	W	L	tGa/tTa	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,87	neutral	-0,97	deleterious	-8,14	high_impact	3,86	neutral	0,61	damaging	0,08	deleterious	4,36	24,1	0,18	0,55	neutral	0,47	disease	0,93	disease	0,76	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,47	0,27	0,9	3,51	6,73	P	0,55	P	0,95	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6923	6923	A	C	MI.4055	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1020	340	W	C	tgA/tgC	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,72	deleterious	-3,86	deleterious	-8,14	high_impact	5,14	damaging	0,56	damaging	0,07	deleterious	4,11	23,7	0,24	0,55	disease	0,9	disease	0,95	disease	0,8	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,65	0,36	0,9	3,51	6,73	P	0,65	P	0,88	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6923	6923	A	T	MI.4056	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1020	340	W	C	tgA/tgT	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,72	deleterious	-3,86	deleterious	-8,14	high_impact	5,14	damaging	0,56	damaging	0,07	deleterious	4,22	23,9	0,24	0,55	disease	0,9	disease	0,95	disease	0,8	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,65	0,36	0,9	3,51	6,73	P	0,65	P	0,88	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6924	6924	G	T	MI.4057	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1021	341	A	S	Gcc/Tcc	1,75	1	0	probably_damaging	1	neutral	0,34	neutral	2,64	neutral	-1,4	neutral	-0,34	neutral_impact	0,1	damaging	0,59	neutral	0,32	deleterious	2,06	16,61	0,33	0,55	neutral	0,32	neutral	0,32	neutral	0,25	neutral	0,45	1	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,71	low_impact	-3,58	medium_impact	0,03	low_impact	-1,01	0,84	0,9	2,34	7,65	N	0,49	N	0,64	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6924	6924	G	A	MI.4058	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1021	341	A	T	Gcc/Acc	1,75	1	0	probably_damaging	1	neutral	0,1	neutral	2,68	neutral	-0,99	neutral	-0,87	low_impact	1,61	damaging	0,56	damaging	0,17	deleterious	2,75	21,1	0,32	0,55	disease	0,52	disease	0,66	neutral	0,3	neutral	0,25	5	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,77	low_impact	-3,58	medium_impact	-0,34	medium_impact	0,39	0,8	0,9	2,34	7,65	P	0,52	P	0,2	disease_causing	1	0,03	.	.	.	.	.	.	COSM1138392	.	.	.	.	.	.	.	.
chrM	6924	6924	G	C	MI.4059	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1021	341	A	P	Gcc/Ccc	1,75	1	0	probably_damaging	1	deleterious	0,01	neutral	2,55	deleterious	-4,32	neutral	-2,06	high_impact	4	damaging	0,52	damaging	0,12	deleterious	3,87	23,5	0,1	0,55	disease	0,74	disease	0,94	disease	0,66	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,58	medium_impact	-0,92	high_impact	2,59	0,81	0,9	2,34	7,65	N	0,39	N	0,85	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8714	8714	C	T	MI.406	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	188	63	T	I	aCt/aTt	-4,5	0	0	benign	0,17	neutral	0,5	neutral	3,85	deleterious	-3,21	neutral	-1,43	neutral_impact	0,58	neutral	0,86	neutral	0,97	deleterious	-0,05	2,14	0,52	0,65	disease	0,69	neutral	0,44	neutral	0,2	disease	0,61	2	neutral	0,4	deleterious	0,67	neutral	-6	neutral	0,23	medium_impact	-0,1	medium_impact	0,29	medium_impact	-0,6	0,51	0,9	18,58	14,48	N	0,37	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6925	6925	C	A	MI.4060	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1022	341	A	D	gCc/gAc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-4,83	neutral	-2,19	high_impact	4,35	damaging	0,56	damaging	0,13	deleterious	4,65	24,5	0,11	0,55	disease	0,66	disease	0,93	disease	0,67	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,92	0,66	0,9	2,34	7,65	N	0,49	N	0,89	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6925	6925	C	G	MI.4061	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1022	341	A	G	gCc/gGc	9,15	1	0	probably_damaging	0,99	neutral	0,06	neutral	2,56	deleterious	-3,47	neutral	-1,67	medium_impact	3,03	damaging	0,58	damaging	0,16	deleterious	2,47	19,3	0,19	0,55	disease	0,65	disease	0,8	neutral	0,5	neutral	0,49	0	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,79	low_impact	-2,64	medium_impact	-0,47	medium_impact	1,7	0,81	0,9	2,34	7,65	P	0,51	P	0,56	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6925	6925	C	T	MI.4062	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1022	341	A	V	gCc/gTc	9,15	1	0	probably_damaging	1	neutral	0,33	neutral	2,76	neutral	-0,31	neutral	-1,55	low_impact	1,5	neutral	0,61	damaging	0,17	neutral	1,47	13,16	0,29	0,55	neutral	0,37	disease	0,75	neutral	0,3	neutral	0,24	5	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,74	low_impact	-3,58	medium_impact	0,02	medium_impact	0,29	0,75	0,9	2,34	7,65	P	0,54	P	0,75	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6927	6927	C	G	MI.4063	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1024	342	L	V	Cta/Gta	-6,81	0	0	probably_damaging	0,99	neutral	0,07	neutral	2,64	neutral	-1,21	neutral	-1,34	medium_impact	2,23	damaging	0,53	damaging	0,12	deleterious	1,81	15,07	0,31	0,55	neutral	0,27	disease	0,59	neutral	0,33	neutral	0,32	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,7	low_impact	-2,64	medium_impact	-0,43	medium_impact	0,96	0,78	0,9	2,34	7,81	N	0,33	N	0,66	polymorphism	0,96	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6927	6927	C	A	MI.4064	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1024	342	L	M	Cta/Ata	-6,81	0	0	probably_damaging	1	neutral	0,18	neutral	2,53	neutral	-2,74	neutral	-0,84	low_impact	1,5	damaging	0,59	damaging	0,23	deleterious	2,66	20,5	0,24	0,55	neutral	0,36	neutral	0,46	neutral	0,33	neutral	0,43	1	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	-0,17	medium_impact	0,29	0,66	0,9	2,34	7,81	N	0,41	N	0,59	polymorphism	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6928	6928	T	A	MI.4065	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1025	342	L	Q	cTa/cAa	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-3,96	deleterious	-3,32	high_impact	4,36	neutral	0,62	damaging	0,08	deleterious	4,11	23,7	0,13	0,55	disease	0,71	disease	0,85	disease	0,56	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,93	0,76	0,9	2,34	7,81	N	0,36	N	0,82	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6928	6928	T	G	MI.4066	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1025	342	L	R	cTa/cGa	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,43	deleterious	-4,42	deleterious	-3,39	high_impact	4,36	neutral	0,61	damaging	0,06	deleterious	4,21	23,9	0,1	0,55	disease	0,69	disease	0,94	disease	0,68	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,93	0,74	0,9	2,34	7,81	N	0,37	N	0,9	polymorphism	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6928	6928	T	C	MI.4067	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1025	342	L	P	cTa/cCa	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-4,67	deleterious	-3,9	high_impact	4,7	damaging	0,57	damaging	0,07	deleterious	3,97	23,6	0,1	0,55	disease	0,76	disease	0,92	disease	0,69	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,24	0,59	0,9	2,34	7,81	N	0,47	N	0,83	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6930	6930	G	C	MI.4068	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1027	343	G	R	Gga/Cga	-4,5	0	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-4,03	deleterious	-4,97	high_impact	5,24	damaging	0,6	damaging	0,08	deleterious	3,96	23,6	0,1	0,55	neutral	0,46	disease	0,94	disease	0,8	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,71	0,9	3,31	7,47	P	0,64	P	0,95	disease_causing	0,77	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6930	6930	G	T	MI.4069	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1027	343	G	W	Gga/Tga	-4,5	0	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-5,39	deleterious	-4,96	high_impact	5,24	neutral	0,61	damaging	0,09	deleterious	4,47	24,2	0,1	0,55	disease	0,89	disease	0,94	disease	0,74	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,46	0,9	3,31	7,47	P	0,59	P	0,83	disease_causing	0,85	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8716	8716	A	C	MI.407	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	190	64	K	Q	Aaa/Caa	-6,35	0	0	probably_damaging	1	neutral	0,4	neutral	4,17	neutral	-1,33	neutral	-2,12	low_impact	1,29	neutral	0,91	neutral	0,65	deleterious	2,1	16,82	0,55	0,65	neutral	0,41	disease	0,64	neutral	0,33	neutral	0,48	0	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,72	low_impact	-3,6	medium_impact	0,19	medium_impact	0,01	0,75	0,9	18,14	20,1	N	0,31	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6931	6931	G	T	MI.4070	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1028	343	G	V	gGa/gTa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,59	neutral	-1,63	deleterious	-5,59	high_impact	4,89	damaging	0,58	damaging	0,09	deleterious	3,84	23,4	0,11	0,55	disease	0,55	disease	0,92	disease	0,7	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,42	0,56	0,9	3,31	7,47	P	0,67	P	0,93	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6931	6931	G	C	MI.4071	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1028	343	G	A	gGa/gCa	9,15	1	0	probably_damaging	1	neutral	0,06	neutral	2,61	neutral	-1,32	deleterious	-3,72	high_impact	4	neutral	0,75	damaging	0,13	deleterious	3,18	22,7	0,23	0,55	neutral	0,25	disease	0,82	disease	0,6	disease	0,56	1	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,76	low_impact	-3,58	medium_impact	-0,47	high_impact	2,59	0,68	0,9	3,31	7,47	P	0,51	P	0,64	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6931	6931	G	A	MI.4072	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1028	343	G	E	gGa/gAa	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-4,21	deleterious	-4,96	high_impact	5,24	damaging	0,56	damaging	0,09	deleterious	4,01	23,6	0,13	0,55	neutral	0,36	disease	0,92	disease	0,79	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,74	0,64	0,9	3,31	7,47	P	0,68	P	0,93	disease_causing	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6933	6933	T	C	MI.4073	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1030	344	F	L	Ttc/Ctc	-8,43	0	0	probably_damaging	0,99	deleterious	0	neutral	2,69	neutral	-1,57	deleterious	-3,7	high_impact	4,71	neutral	0,74	damaging	0,05	deleterious	4,2	23,9	0,35	0,55	disease	0,76	disease	0,87	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	3,25	0,63	0,9	2,14	6,69	P	0,61	P	0,83	polymorphism	0,82	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6933	6933	T	A	MI.4074	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1030	344	F	I	Ttc/Atc	-8,43	0	0	probably_damaging	1	deleterious	0	neutral	2,66	neutral	-2,57	deleterious	-3,7	high_impact	4,46	neutral	0,74	damaging	0,08	deleterious	4,51	24,3	0,22	0,55	disease	0,81	disease	0,9	disease	0,69	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,02	0,62	0,9	2,14	6,69	N	0,41	N	0,88	polymorphism	0,83	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6933	6933	T	G	MI.4075	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1030	344	F	V	Ttc/Gtc	-8,43	0	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-2,25	deleterious	-4,32	high_impact	4,57	neutral	0,72	damaging	0,06	deleterious	4,23	23,9	0,23	0,55	disease	0,75	disease	0,91	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,12	0,63	0,9	2,14	6,69	N	0,44	N	0,84	polymorphism	0,7	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6934	6934	T	A	MI.4076	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1031	344	F	Y	tTc/tAc	7,53	1	0	probably_damaging	0,99	deleterious	0,01	neutral	2,65	deleterious	-3,82	neutral	-1,85	high_impact	5,26	neutral	0,69	damaging	0,07	deleterious	4,49	24,3	0,25	0,55	disease	0,8	disease	0,86	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,64	medium_impact	-0,92	high_impact	3,76	0,65	0,9	2,14	6,69	P	0,76	P	0,59	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6934	6934	T	C	MI.4077	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1031	344	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,8	neutral	-2,82	deleterious	-4,93	high_impact	4,22	neutral	0,75	damaging	0,08	deleterious	4,4	24,1	0,18	0,55	neutral	0,35	disease	0,88	disease	0,67	disease	0,6	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,8	0,65	0,9	2,14	6,69	N	0,5	N	0,84	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6934	6934	T	G	MI.4078	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1031	344	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,64	deleterious	-4,58	deleterious	-4,94	high_impact	4,36	neutral	0,72	damaging	0,05	deleterious	4,21	23,9	0,19	0,55	disease	0,89	disease	0,91	disease	0,72	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,93	0,4	0,9	2,14	6,69	N	0,48	N	0,91	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6935	6935	C	A	MI.4079	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1032	344	F	L	ttC/ttA	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,69	neutral	-1,57	deleterious	-3,7	high_impact	4,71	neutral	0,74	damaging	0,05	deleterious	4,78	24,7	0,35	0,55	disease	0,76	disease	0,87	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	3,25	0,63	0,9	2,14	6,69	P	0,7	P	0,83	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8716	8716	A	G	MI.408	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	190	64	K	E	Aaa/Gaa	-6,35	0	0	probably_damaging	0,99	neutral	0,74	neutral	4,2	neutral	-0,19	neutral	-2,19	low_impact	0,98	neutral	0,88	damaging	0,28	deleterious	2,51	19,53	0,37	0,65	neutral	0,35	disease	0,78	neutral	0,43	disease	0,53	1	deleterious	0,99	neutral	0,38	neutral	-2	deleterious	0,75	low_impact	-2,65	medium_impact	0,55	medium_impact	-0,26	0,67	0,9	18,14	20,1	N	0,19	N	0,91	polymorphism	1	0,03	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	6935	6935	C	G	MI.4080	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1032	344	F	L	ttC/ttG	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,69	neutral	-1,57	deleterious	-3,7	high_impact	4,71	neutral	0,74	damaging	0,05	deleterious	4,45	24,2	0,35	0,55	disease	0,76	disease	0,87	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	3,25	0,63	0,9	2,14	6,69	P	0,7	P	0,83	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6936	6936	A	G	MI.4081	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1033	345	I	V	Atc/Gtc	-5,66	0	0	probably_damaging	0,92	neutral	0,26	neutral	2,67	neutral	-0,08	neutral	-0,09	neutral_impact	0,76	neutral	0,68	neutral	0,71	neutral	-0,77	0,05	0,53	0,6	neutral	0,27	neutral	0,12	neutral	0,37	neutral	0,29	4	neutral	0,93	neutral	0,17	neutral	-2	deleterious	0,56	low_impact	-1,76	medium_impact	-0,06	medium_impact	-0,4	0,7	0,9	3,7	6,94	N	0,47	N	0,23	polymorphism	0,65	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6936	6936	A	T	MI.4082	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1033	345	I	F	Atc/Ttc	-5,66	0	0	probably_damaging	1	deleterious	0,01	neutral	2,54	neutral	-2,5	neutral	-2,41	high_impact	4,16	neutral	0,6	neutral	0,39	deleterious	3,62	23,2	0,3	0,55	disease	0,56	disease	0,88	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,58	medium_impact	-0,92	high_impact	2,74	0,81	0,9	3,7	6,94	N	0,37	N	0,85	disease_causing	0,99	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6936	6936	A	C	MI.4083	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1033	345	I	L	Atc/Ctc	-5,66	0	0	probably_damaging	0,97	neutral	0,12	neutral	2,75	neutral	-0,17	neutral	-1,16	low_impact	1,5	neutral	0,65	neutral	0,55	deleterious	1,98	16,06	0,31	0,55	neutral	0,21	disease	0,65	neutral	0,34	neutral	0,24	5	deleterious	0,99	neutral	0,08	neutral	-2	deleterious	0,6	low_impact	-2,18	medium_impact	-0,29	medium_impact	0,29	0,76	0,9	3,7	6,94	N	0,44	N	0,61	disease_causing	0,55	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6937	6937	T	A	MI.4084	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1034	345	I	N	aTc/aAc	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-4,12	deleterious	-3,99	high_impact	4,01	neutral	0,61	neutral	0,43	deleterious	4,47	24,2	0,22	0,55	disease	0,73	disease	0,91	disease	0,65	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,6	0,79	0,9	3,7	6,94	P	0,5	N	0,94	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6937	6937	T	G	MI.4085	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1034	345	I	S	aTc/aGc	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,56	neutral	-2,33	deleterious	-3,38	high_impact	4,16	neutral	0,67	neutral	0,5	deleterious	4,27	23,9	0,2	0,55	disease	0,57	disease	0,88	disease	0,64	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,74	0,65	0,9	3,7	6,94	P	0,5	N	0,62	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6937	6937	T	C	MI.4086	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1034	345	I	T	aTc/aCc	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,58	neutral	-2,6	deleterious	-2,51	high_impact	4,71	neutral	0,61	neutral	0,4	deleterious	3,2	22,7	0,4	0,55	disease	0,52	disease	0,73	disease	0,63	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	3,25	0,78	0,9	3,7	6,94	P	0,68	P	0,76	disease_causing	1	0,36	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	6938	6938	C	A	MI.4087	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1035	345	I	M	atC/atA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,55	neutral	-1,38	neutral	-1,48	medium_impact	3,42	neutral	0,66	neutral	0,53	deleterious	3,81	23,4	0,38	0,55	neutral	0,47	disease	0,71	disease	0,53	disease	0,59	2	deleterious	1	neutral	0	deleterious	5	deleterious	0,72	low_impact	-3,58	low_impact	-1,48	high_impact	2,06	0,83	0,9	3,7	6,94	P	0,5	N	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6938	6938	C	G	MI.4088	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1035	345	I	M	atC/atG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,55	neutral	-1,38	neutral	-1,48	medium_impact	3,42	neutral	0,66	neutral	0,53	deleterious	3,37	22,9	0,38	0,55	neutral	0,47	disease	0,71	disease	0,53	disease	0,59	2	deleterious	1	neutral	0	deleterious	5	deleterious	0,72	low_impact	-3,58	low_impact	-1,48	high_impact	2,06	0,83	0,9	3,7	6,94	P	0,5	N	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6939	6939	T	C	MI.4089	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1036	346	F	L	Ttt/Ctt	-3,11	0	0	probably_damaging	0,98	deleterious	0,02	neutral	2,8	neutral	-0,02	deleterious	-3,58	medium_impact	2,84	neutral	0,74	damaging	0,06	deleterious	4,1	23,7	0,34	0,55	neutral	0,25	disease	0,86	neutral	0,45	neutral	0,37	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,73	low_impact	-2,35	medium_impact	-0,75	medium_impact	1,52	0,66	0,9	3,9	6,99	N	0,26	N	0,83	polymorphism	0,86	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8717	8717	A	T	MI.409	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	191	64	K	M	aAa/aTa	0,82	0	0	probably_damaging	1	neutral	0,09	neutral	4,09	deleterious	-3,67	deleterious	-3,58	medium_impact	2,13	neutral	0,86	damaging	0,21	deleterious	3,8	23,4	0,26	0,65	disease	0,82	disease	0,64	neutral	0,38	disease	0,56	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	-0,28	medium_impact	0,73	0,47	0,9	18,14	20,1	N	0,34	N	0,81	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6939	6939	T	G	MI.4090	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1036	346	F	V	Ttt/Gtt	-3,11	0	0	probably_damaging	1	deleterious	0,03	neutral	2,89	neutral	0,54	deleterious	-4,17	medium_impact	2,33	neutral	0,72	damaging	0,07	deleterious	4,06	23,7	0,25	0,55	neutral	0,27	disease	0,9	neutral	0,46	neutral	0,37	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,65	medium_impact	1,05	0,64	0,9	3,9	6,99	N	0,25	N	0,84	polymorphism	0,76	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6939	6939	T	A	MI.4091	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1036	346	F	I	Ttt/Att	-3,11	0	0	probably_damaging	0,99	neutral	0,07	neutral	2,84	neutral	0,25	deleterious	-3,58	medium_impact	2,58	neutral	0,73	damaging	0,08	deleterious	4,44	24,2	0,15	0,55	neutral	0,29	disease	0,87	neutral	0,44	neutral	0,38	2	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,76	low_impact	-2,64	medium_impact	-0,43	medium_impact	1,28	0,64	0,9	3,9	6,99	N	0,27	N	0,88	polymorphism	0,87	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6940	6940	T	C	MI.4092	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1037	346	F	S	tTt/tCt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,64	neutral	-2,43	deleterious	-4,8	medium_impact	3,39	neutral	0,76	damaging	0,08	deleterious	4,27	24	0,22	0,55	neutral	0,42	disease	0,89	disease	0,62	disease	0,7	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,03	0,68	0,9	3,9	6,99	N	0,44	N	0,84	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6940	6940	T	G	MI.4093	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1037	346	F	C	tTt/tGt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-3,32	deleterious	-4,8	high_impact	3,77	neutral	0,74	damaging	0,06	deleterious	4,19	23,8	0,19	0,55	neutral	0,47	disease	0,93	disease	0,59	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,38	0,42	0,9	3,9	6,99	N	0,42	N	0,91	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6940	6940	T	A	MI.4094	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1037	346	F	Y	tTt/tAt	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,62	neutral	-2,93	neutral	-1,67	high_impact	3,92	neutral	0,73	damaging	0,07	deleterious	4,3	24	0,24	0,55	disease	0,56	disease	0,87	disease	0,57	disease	0,59	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,35	low_impact	-1,48	high_impact	2,52	0,65	0,9	3,9	6,99	N	0,51	P	0,59	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6941	6941	T	A	MI.4095	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1038	346	F	L	ttT/ttA	5,91	1	0,01	probably_damaging	0,98	deleterious	0,02	neutral	2,8	neutral	-0,02	deleterious	-3,58	medium_impact	2,84	neutral	0,74	damaging	0,06	deleterious	4,61	24,4	0,34	0,55	neutral	0,25	disease	0,86	neutral	0,45	neutral	0,37	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,73	low_impact	-2,35	medium_impact	-0,75	medium_impact	1,52	0,66	0,9	3,9	6,99	P	0,51	P	0,83	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6941	6941	T	G	MI.4096	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1038	346	F	L	ttT/ttG	5,91	1	0,01	probably_damaging	0,98	deleterious	0,02	neutral	2,8	neutral	-0,02	deleterious	-3,58	medium_impact	2,84	neutral	0,74	damaging	0,06	deleterious	4,47	24,2	0,34	0,55	neutral	0,25	disease	0,86	neutral	0,45	neutral	0,37	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,73	low_impact	-2,35	medium_impact	-0,75	medium_impact	1,52	0,66	0,9	3,9	6,99	P	0,5	N	0,83	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6942	6942	C	A	MI.4097	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1039	347	L	I	Ctt/Att	-0,1	0	0	probably_damaging	1	deleterious	0	neutral	2,51	neutral	-1,95	neutral	-1,22	high_impact	4,15	damaging	0,49	damaging	0,13	deleterious	4,23	23,9	0,35	0,55	neutral	0,26	disease	0,81	disease	0,52	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,73	0,75	0,9	2,34	6,78	N	0,4	N	0,54	polymorphism	0,96	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6942	6942	C	T	MI.4098	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1039	347	L	F	Ctt/Ttt	-0,1	0	0	probably_damaging	1	deleterious	0	neutral	2,47	neutral	-2,54	neutral	-2,44	high_impact	3,73	damaging	0,41	damaging	0,09	deleterious	4,02	23,6	0,39	0,55	disease	0,58	disease	0,85	disease	0,54	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,35	0,68	0,9	2,34	6,78	N	0,44	N	0,87	polymorphism	0,7	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6942	6942	C	G	MI.4099	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1039	347	L	V	Ctt/Gtt	-0,1	0	0	probably_damaging	0,99	deleterious	0	neutral	2,52	neutral	-1,85	neutral	-1,84	high_impact	4,32	damaging	0,47	damaging	0,11	deleterious	3,52	23,1	0,36	0,55	neutral	0,38	disease	0,78	disease	0,53	disease	0,55	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-2,64	low_impact	-1,48	high_impact	2,89	0,74	0,9	2,34	6,78	N	0,41	N	0,66	polymorphism	0,92	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8544	8544	C	A	MI.41	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	18	6	F	L	ttC/ttA	5,91	1	0	probably_damaging	0,92	deleterious	0,01	neutral	4,01	neutral	-0,1	deleterious	-5,08	medium_impact	3,32	damaging	0,56	neutral	0,6	deleterious	7,51	34	0,46	0,65	disease	0,61	disease	0,63	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,73	low_impact	-1,76	medium_impact	-0,84	medium_impact	1,75	0,33	0,9	39,82	8,43	P	0,58	P	0,89	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8717	8717	A	C	MI.410	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	191	64	K	T	aAa/aCa	0,82	0	0	probably_damaging	0,99	neutral	0,39	neutral	4,18	neutral	-1,88	deleterious	-3,21	low_impact	1,47	neutral	0,89	neutral	0,3	deleterious	2,36	18,56	0,36	0,65	neutral	0,39	disease	0,62	neutral	0,34	neutral	0,46	1	deleterious	0,99	neutral	0,2	neutral	-2	deleterious	0,72	low_impact	-2,65	medium_impact	0,18	medium_impact	0,16	0,46	0,9	18,14	20,1	N	0,33	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6943	6943	T	C	MI.4100	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1040	347	L	P	cTt/cCt	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,41	deleterious	-4,98	deleterious	-4,29	high_impact	4,57	damaging	0,42	damaging	0,11	deleterious	3,77	23,4	0,13	0,55	disease	0,76	disease	0,89	disease	0,72	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,12	0,68	0,9	2,34	6,78	N	0,47	N	0,83	disease_causing	0,96	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6943	6943	T	A	MI.4101	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1040	347	L	H	cTt/cAt	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-4,16	deleterious	-4,29	high_impact	5,12	damaging	0,53	damaging	0,09	deleterious	4,04	23,7	0,15	0,55	disease	0,75	disease	0,9	disease	0,69	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,63	0,68	0,9	2,34	6,78	P	0,63	P	0,83	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6943	6943	T	G	MI.4102	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1040	347	L	R	cTt/cGt	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-4,35	deleterious	-3,67	high_impact	5,12	damaging	0,49	damaging	0,1	deleterious	4,05	23,7	0,11	0,55	disease	0,68	disease	0,95	disease	0,72	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,63	0,68	0,9	2,34	6,78	P	0,61	P	0,9	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6945	6945	T	C	MI.4103	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1042	348	F	L	Ttc/Ctc	-7,51	0	0	probably_damaging	1	deleterious	0	neutral	2,14	deleterious	-3,84	deleterious	-3,67	high_impact	4,55	neutral	0,68	damaging	0,15	deleterious	4,11	23,7	0,33	0,55	disease	0,77	disease	0,89	disease	0,68	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,1	0,59	0,9	NA	NA	N	0,45	N	0,83	polymorphism	0,74	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6945	6945	T	G	MI.4104	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1042	348	F	V	Ttc/Gtc	-7,51	0	0	probably_damaging	1	deleterious	0	neutral	2,08	deleterious	-5,4	deleterious	-4,28	high_impact	5,25	neutral	0,65	damaging	0,16	deleterious	4,15	23,8	0,23	0,55	disease	0,85	disease	0,93	disease	0,75	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,75	0,53	0,9	NA	NA	P	0,66	P	0,84	polymorphism	0,59	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6945	6945	T	A	MI.4105	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1042	348	F	I	Ttc/Atc	-7,51	0	0	probably_damaging	1	deleterious	0	neutral	2,07	deleterious	-5,51	deleterious	-3,67	high_impact	3,93	neutral	0,72	damaging	0,19	deleterious	4,5	24,3	0,17	0,55	disease	0,86	disease	0,9	disease	0,74	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,53	0,59	0,9	NA	NA	N	0,3	N	0,88	polymorphism	0,76	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6946	6946	T	G	MI.4106	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1043	348	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,05	deleterious	-7,31	deleterious	-4,89	high_impact	4,9	neutral	0,7	damaging	0,16	deleterious	4,16	23,8	0,22	0,55	disease	0,96	disease	0,93	disease	0,75	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,43	0,35	0,9	NA	NA	P	0,65	P	0,91	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6946	6946	T	A	MI.4107	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1043	348	F	Y	tTc/tAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,33	neutral	-2,13	neutral	-1,83	high_impact	4,9	neutral	0,71	damaging	0,16	deleterious	4,25	23,9	0,2	0,55	disease	0,69	disease	0,89	disease	0,69	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,43	0,64	0,9	NA	NA	P	0,75	P	0,59	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6946	6946	T	C	MI.4108	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1043	348	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,08	deleterious	-5,18	deleterious	-4,89	high_impact	4,01	neutral	0,66	damaging	0,22	deleterious	4,35	24,1	0,23	0,55	disease	0,88	disease	0,9	disease	0,73	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,6	0,49	0,9	NA	NA	P	0,52	P	0,84	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6947	6947	C	A	MI.4109	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1044	348	F	L	ttC/ttA	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,14	deleterious	-3,84	deleterious	-3,67	high_impact	4,55	neutral	0,68	damaging	0,15	deleterious	4,7	24,6	0,33	0,55	disease	0,77	disease	0,89	disease	0,68	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,1	0,59	0,9	NA	NA	P	0,58	P	0,83	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8718	8718	A	T	MI.411	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	192	64	K	N	aaA/aaT	0,13	0	0	probably_damaging	1	neutral	0,52	neutral	4,17	neutral	-1,84	neutral	-2,35	low_impact	1,09	neutral	0,81	neutral	0,33	deleterious	2,63	20,4	0,66	0,7	neutral	0,34	disease	0,53	neutral	0,31	neutral	0,46	1	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,31	medium_impact	-0,16	0,62	0,9	18,14	20,1	N	0,23	N	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6947	6947	C	G	MI.4110	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1044	348	F	L	ttC/ttG	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,14	deleterious	-3,84	deleterious	-3,67	high_impact	4,55	neutral	0,68	damaging	0,15	deleterious	4,42	24,2	0,33	0,55	disease	0,77	disease	0,89	disease	0,68	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,1	0,59	0,9	NA	NA	P	0,57	P	0,83	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6948	6948	A	T	MI.4111	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1045	349	T	S	Acc/Tcc	-0,8	0,06	0	probably_damaging	0,99	deleterious	0,01	neutral	2,66	neutral	-1,91	neutral	-2,41	medium_impact	2,75	neutral	0,71	damaging	0,11	deleterious	3,35	22,9	0,33	0,55	disease	0,52	disease	0,81	disease	0,59	neutral	0,38	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-2,64	medium_impact	-0,92	medium_impact	1,44	0,56	0,9	3,31	6,76	N	0,27	N	0,79	disease_causing	0,83	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6948	6948	A	G	MI.4112	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1045	349	T	A	Acc/Gcc	-0,8	0,06	0	probably_damaging	0,99	deleterious	0,01	neutral	2,7	neutral	-1,04	deleterious	-3,03	high_impact	4,42	neutral	0,74	damaging	0,07	deleterious	3,58	23,2	0,45	0,55	neutral	0,42	disease	0,83	disease	0,61	disease	0,55	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-2,64	medium_impact	-0,92	high_impact	2,98	0,46	0,9	3,31	6,76	N	0,38	N	0,69	disease_causing	0,93	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6948	6948	A	C	MI.4113	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1045	349	T	P	Acc/Ccc	-0,8	0,06	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-3,91	deleterious	-3,65	high_impact	4,77	damaging	0,59	damaging	0,09	deleterious	3,56	23,1	0,16	0,55	neutral	0,29	disease	0,92	disease	0,74	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,31	0,52	0,9	3,31	6,76	P	0,64	P	0,92	disease_causing	0,99	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6949	6949	C	A	MI.4114	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1046	349	T	N	aCc/aAc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,63	neutral	-2,68	deleterious	-3,03	high_impact	4,42	neutral	0,66	damaging	0,06	deleterious	3,75	23,3	0,35	0,55	disease	0,68	disease	0,92	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,98	0,67	0,9	3,31	6,76	N	0,5	N	0,8	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6949	6949	C	T	MI.4115	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1046	349	T	I	aCc/aTc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,79	neutral	-0,14	deleterious	-3,65	high_impact	3,87	neutral	0,71	damaging	0,05	deleterious	4,07	23,7	0,31	0,55	neutral	0,3	disease	0,94	disease	0,67	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,47	0,64	0,9	3,31	6,76	N	0,45	N	0,92	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6949	6949	C	G	MI.4116	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1046	349	T	S	aCc/aGc	8,69	1	0	probably_damaging	0,99	deleterious	0,01	neutral	2,66	neutral	-1,91	neutral	-2,41	medium_impact	2,75	neutral	0,71	damaging	0,11	deleterious	3,57	23,1	0,33	0,55	disease	0,52	disease	0,81	disease	0,59	neutral	0,38	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-2,64	medium_impact	-0,92	medium_impact	1,44	0,56	0,9	3,31	6,76	N	0,41	N	0,79	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6951	6951	G	A	MI.4117	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1048	350	V	M	Gta/Ata	-7,28	0	0	benign	0,12	neutral	0,13	neutral	2,71	neutral	-1,08	neutral	-0,48	neutral_impact	0,42	neutral	0,67	neutral	0,66	deleterious	0,63	8,36	0,38	0,55	neutral	0,5	disease	0,51	neutral	0,36	neutral	0,4	2	neutral	0,85	deleterious	0,51	neutral	-6	neutral	0,21	medium_impact	0,06	medium_impact	-0,27	medium_impact	-0,71	0,91	0,95	12,09	24,13	N	0,41	N	0,75	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6951	6951	G	T	MI.4118	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1048	350	V	L	Gta/Tta	-7,28	0	0	benign	0,02	neutral	0,23	neutral	2,86	neutral	0,43	neutral	-0,41	neutral_impact	0,41	neutral	0,64	neutral	0,64	deleterious	0,5	7,46	0,32	0,55	neutral	0,27	disease	0,62	neutral	0,33	neutral	0,38	2	neutral	0,76	deleterious	0,61	neutral	-6	neutral	0,18	medium_impact	0,83	medium_impact	-0,1	medium_impact	-0,72	0,66	0,9	12,09	24,13	N	0,43	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6951	6951	G	C	MI.4119	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1048	350	V	L	Gta/Cta	-7,28	0	0	benign	0,02	neutral	0,23	neutral	2,86	neutral	0,43	neutral	-0,41	neutral_impact	0,41	neutral	0,64	neutral	0,64	deleterious	0,4	6,58	0,32	0,55	neutral	0,27	disease	0,62	neutral	0,33	neutral	0,38	2	neutral	0,76	deleterious	0,61	neutral	-6	neutral	0,18	medium_impact	0,83	medium_impact	-0,1	medium_impact	-0,72	0,66	0,9	12,09	24,13	N	0,42	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8718	8718	A	C	MI.412	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	192	64	K	N	aaA/aaC	0,13	0	0	probably_damaging	1	neutral	0,52	neutral	4,17	neutral	-1,84	neutral	-2,35	low_impact	1,09	neutral	0,81	neutral	0,33	deleterious	2,53	19,65	0,66	0,7	neutral	0,34	disease	0,53	neutral	0,31	neutral	0,46	1	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,31	medium_impact	-0,16	0,62	0,9	18,14	20,1	N	0,23	N	0,88	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6952	6952	T	A	MI.4120	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1049	350	V	E	gTa/gAa	0,82	0,54	0	possibly_damaging	0,66	deleterious	0	neutral	2,64	deleterious	-3,36	deleterious	-3,01	high_impact	3,98	neutral	0,63	neutral	0,43	deleterious	4,49	24,3	0,09	0,55	disease	0,84	disease	0,92	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,17	deleterious	5	deleterious	0,72	low_impact	-1,03	low_impact	-1,48	high_impact	2,58	0,41	0,9	12,09	24,13	N	0,36	N	0,92	polymorphism	0,85	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6952	6952	T	G	MI.4121	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1049	350	V	G	gTa/gGa	0,82	0,54	0	possibly_damaging	0,81	deleterious	0	neutral	2,79	neutral	-0,13	deleterious	-3,59	medium_impact	3,28	neutral	0,69	neutral	0,59	deleterious	3,72	23,3	0,14	0,55	disease	0,83	disease	0,83	disease	0,64	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	4	deleterious	0,74	low_impact	-1,35	low_impact	-1,48	medium_impact	1,93	0,42	0,9	12,09	24,13	N	0,3	N	0,76	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6952	6952	T	C	MI.4122	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1049	350	V	A	gTa/gCa	0,82	0,54	0	possibly_damaging	0,44	deleterious	0	neutral	2,73	neutral	-0,88	neutral	-1,89	medium_impact	3,08	neutral	0,69	neutral	0,67	deleterious	2,03	16,4	0,28	0,55	neutral	0,49	disease	0,68	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,28	deleterious	4	neutral	0,37	medium_impact	-0,66	low_impact	-1,48	medium_impact	1,75	0,63	0,9	12,09	24,13	N	0,35	N	0,67	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6954	6954	G	T	MI.4123	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1051	351	G	C	Ggt/Tgt	-11,44	0	0	probably_damaging	1	deleterious	0	neutral	2,01	deleterious	-6,75	deleterious	-5,47	high_impact	5,26	damaging	0,45	damaging	0,16	deleterious	4,19	23,8	0,12	0,55	disease	0,9	disease	0,96	disease	0,78	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,46	0,9	1,56	6,79	P	0,54	P	0,98	disease_causing	0,56	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6954	6954	G	A	MI.4124	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1051	351	G	S	Ggt/Agt	-11,44	0	0	probably_damaging	1	deleterious	0	neutral	2,16	deleterious	-3	deleterious	-3,64	high_impact	4,92	damaging	0,45	damaging	0,24	deleterious	4,24	23,9	0,18	0,55	disease	0,67	disease	0,91	disease	0,77	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,54	0,9	1,56	6,79	P	0,7	P	0,73	polymorphism	0,76	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6954	6954	G	C	MI.4125	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1051	351	G	R	Ggt/Cgt	-11,44	0	0	probably_damaging	1	deleterious	0	neutral	2	deleterious	-7,54	deleterious	-4,87	high_impact	4,92	damaging	0,49	damaging	0,15	deleterious	4,01	23,6	0,11	0,55	disease	0,9	disease	0,96	disease	0,84	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,93	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,63	0,9	1,56	6,79	P	0,56	P	0,95	polymorphism	0,6	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6955	6955	G	A	MI.4126	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1052	351	G	D	gGt/gAt	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2	deleterious	-7,1	deleterious	-4,26	high_impact	5,26	damaging	0,44	damaging	0,17	deleterious	3,87	23,5	0,14	0,55	disease	0,9	disease	0,94	disease	0,84	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,38	0,9	1,56	6,79	P	0,83	P	0,97	disease_causing	1	0,49	.	.	.	.	.	.	COSM1155665	.	.	G6955A	Mild EXIT and MR	+	+	Reported	1
chrM	6955	6955	G	T	MI.4127	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1052	351	G	V	gGt/gTt	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,02	deleterious	-5,77	deleterious	-5,47	high_impact	5,26	damaging	0,46	damaging	0,19	deleterious	3,88	23,5	0,11	0,55	neutral	0,38	disease	0,95	disease	0,79	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,44	0,9	1,56	6,79	P	0,62	P	0,93	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6955	6955	G	C	MI.4128	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1052	351	G	A	gGt/gCt	9,15	1	0	probably_damaging	1	deleterious	0	neutral	2,42	neutral	-1,55	deleterious	-3,65	high_impact	4,71	neutral	0,62	neutral	0,33	deleterious	3,2	22,7	0,17	0,55	disease	0,5	disease	0,86	disease	0,74	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,25	0,58	0,9	1,56	6,79	P	0,71	P	0,64	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6957	6957	G	A	MI.4129	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1054	352	G	S	Ggc/Agc	-6,81	0	0	probably_damaging	1	deleterious	0	neutral	1,44	deleterious	-3,84	deleterious	-3,65	high_impact	4,92	damaging	0,48	damaging	0,02	deleterious	4,26	23,9	0,19	0,55	neutral	0,37	disease	0,91	disease	0,73	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,6	0,9	2,14	6,72	P	0,61	P	0,73	disease_causing	0,53	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8719	8719	G	T	MI.413	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	193	65	G	W	Gga/Tga	-1,26	0	0	probably_damaging	1	neutral	0,07	neutral	4,28	deleterious	-6,63	deleterious	-7,23	high_impact	4,09	neutral	0,63	damaging	0,25	deleterious	4,33	24	0,25	0,65	disease	0,8	disease	0,88	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,34	high_impact	2,41	0,39	0,9	49,12	8,59	N	0,33	N	0,99	disease_causing	0,97	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6957	6957	G	T	MI.4130	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1054	352	G	C	Ggc/Tgc	-6,81	0	0	probably_damaging	1	deleterious	0	neutral	1,3	deleterious	-6,28	deleterious	-5,48	high_impact	5,26	damaging	0,4	damaging	0,01	deleterious	4,3	24	0,12	0,55	disease	0,92	disease	0,95	disease	0,75	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,47	0,9	2,14	6,72	P	0,52	P	0,98	disease_causing	0,82	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6957	6957	G	C	MI.4131	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1054	352	G	R	Ggc/Cgc	-6,81	0	0	probably_damaging	1	deleterious	0	neutral	1,27	deleterious	-8,17	deleterious	-4,87	high_impact	4,92	damaging	0,45	damaging	0,02	deleterious	4,07	23,7	0,13	0,55	disease	0,92	disease	0,95	disease	0,83	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,93	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,54	0,9	2,14	6,72	P	0,52	P	0,95	disease_causing	0,7	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6958	6958	G	A	MI.4132	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1055	352	G	D	gGc/gAc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	1,27	deleterious	-8,25	deleterious	-4,26	high_impact	5,26	damaging	0,33	damaging	0,01	deleterious	3,91	23,5	0,11	0,55	disease	0,88	disease	0,93	disease	0,82	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,38	0,9	2,14	6,72	P	0,72	P	0,97	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6958	6958	G	T	MI.4133	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1055	352	G	V	gGc/gTc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	1,28	deleterious	-7,16	deleterious	-5,48	high_impact	5,26	damaging	0,47	damaging	0,02	deleterious	3,86	23,5	0,13	0,55	disease	0,87	disease	0,94	disease	0,76	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,51	0,9	2,14	6,72	P	0,62	P	0,93	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6958	6958	G	C	MI.4134	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1055	352	G	A	gGc/gCc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	1,33	deleterious	-5,31	deleterious	-3,65	high_impact	5,26	damaging	0,57	damaging	0,03	deleterious	3,15	22,6	0,18	0,55	disease	0,66	disease	0,84	disease	0,75	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,67	0,9	2,14	6,72	P	0,71	P	0,64	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6960	6960	C	G	MI.4135	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1057	353	L	V	Ctg/Gtg	-20	0	0,01	probably_damaging	0,99	neutral	0,06	neutral	2,78	neutral	-0,13	neutral	-1,39	medium_impact	2,3	damaging	0,41	neutral	0,47	deleterious	3,52	23,1	0,44	0,55	neutral	0,25	disease	0,56	neutral	0,4	neutral	0,2	6	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,71	low_impact	-2,64	medium_impact	-0,47	medium_impact	1,03	0,75	0,9	3,12	6,69	P	0,57	P	0,66	polymorphism	0,96	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6960	6960	C	A	MI.4136	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1057	353	L	M	Ctg/Atg	-20	0	0,01	probably_damaging	1	deleterious	0,03	neutral	2,54	neutral	-2,44	neutral	-0,98	medium_impact	3,21	damaging	0,49	neutral	0,66	deleterious	3,77	23,4	0,32	0,55	disease	0,52	disease	0,67	disease	0,54	neutral	0,49	0	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,74	low_impact	-3,58	medium_impact	-0,65	medium_impact	1,87	0,8	0,9	3,12	6,69	N	0,45	N	0,59	polymorphism	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6961	6961	T	G	MI.4137	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1058	353	L	R	cTg/cGg	-0,1	0,01	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-4,37	deleterious	-3,46	high_impact	5,03	damaging	0,45	neutral	0,32	deleterious	4,27	23,9	0,17	0,55	disease	0,72	disease	0,94	disease	0,77	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,55	0,56	0,9	3,12	6,69	P	0,69	P	0,9	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6961	6961	T	A	MI.4138	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1058	353	L	Q	cTg/cAg	-0,1	0,01	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-4,55	deleterious	-3,42	high_impact	5,03	damaging	0,45	neutral	0,41	deleterious	4,28	24	0,18	0,55	disease	0,74	disease	0,88	disease	0,67	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,55	0,75	0,9	3,12	6,69	P	0,67	P	0,82	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6961	6961	T	C	MI.4139	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1058	353	L	P	cTg/cCg	-0,1	0,01	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-4,92	deleterious	-3,97	high_impact	4,48	damaging	0,3	neutral	0,36	deleterious	3,95	23,6	0,18	0,55	disease	0,79	disease	0,9	disease	0,76	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,04	0,64	0,9	3,12	6,69	P	0,72	P	0,83	disease_causing	0,99	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8719	8719	G	C	MI.414	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	193	65	G	R	Gga/Cga	-1,26	0	0	probably_damaging	1	neutral	0,13	neutral	4,37	deleterious	-3,81	deleterious	-7,17	medium_impact	3,06	damaging	0,59	damaging	0,25	deleterious	3,86	23,5	0,26	0,65	disease	0,7	disease	0,89	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	-0,18	medium_impact	1,53	0,65	0,9	49,12	8,59	N	0,28	N	0,98	disease_causing	0,95	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6963	6963	A	G	MI.4140	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1060	354	T	A	Act/Gct	-1,95	0	0	probably_damaging	0,99	deleterious	0	neutral	2,49	neutral	-2,59	deleterious	-3,02	high_impact	5,22	neutral	0,72	damaging	0,06	deleterious	3,58	23,2	0,47	0,55	disease	0,67	disease	0,78	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	3,72	0,49	0,9	2,34	7,35	P	0,67	P	0,69	polymorphism	0,93	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6963	6963	A	C	MI.4141	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1060	354	T	P	Act/Cct	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	2,43	deleterious	-4,25	deleterious	-3,63	high_impact	5,22	damaging	0,57	damaging	0,08	deleterious	3,56	23,1	0,19	0,55	disease	0,89	disease	0,9	disease	0,82	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,72	0,57	0,9	2,34	7,35	P	0,7	P	0,92	polymorphism	0,73	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6963	6963	A	T	MI.4142	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1060	354	T	S	Act/Tct	-1,95	0	0	probably_damaging	0,99	deleterious	0,04	neutral	2,55	neutral	-1,59	neutral	-2,41	medium_impact	2,79	neutral	0,69	damaging	0,07	deleterious	3,39	23	0,39	0,55	disease	0,55	disease	0,8	disease	0,55	neutral	0,45	1	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,79	low_impact	-2,64	medium_impact	-0,58	medium_impact	1,48	0,7	0,9	2,34	7,35	N	0,24	N	0,79	polymorphism	0,98	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6964	6964	C	A	MI.4143	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1061	354	T	N	aCt/aAt	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,45	deleterious	-3,6	deleterious	-3,02	high_impact	5,22	neutral	0,63	damaging	0,04	deleterious	3,64	23,2	0,42	0,55	disease	0,88	disease	0,89	disease	0,75	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,72	0,85	0,9	2,34	7,35	P	0,74	P	0,8	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6964	6964	C	G	MI.4144	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1061	354	T	S	aCt/aGt	6,84	1	0	probably_damaging	0,99	deleterious	0,04	neutral	2,55	neutral	-1,59	neutral	-2,41	medium_impact	2,79	neutral	0,69	damaging	0,07	deleterious	3,59	23,2	0,39	0,55	disease	0,55	disease	0,8	disease	0,55	neutral	0,45	1	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,79	low_impact	-2,64	medium_impact	-0,58	medium_impact	1,48	0,7	0,9	2,34	7,35	N	0,43	N	0,79	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6964	6964	C	T	MI.4145	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1061	354	T	I	aCt/aTt	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-4,23	deleterious	-3,62	high_impact	4,53	neutral	0,69	damaging	0,04	deleterious	4,03	23,7	0,42	0,55	disease	0,92	disease	0,92	disease	0,74	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,08	0,63	0,9	2,34	7,35	P	0,53	P	0,92	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6966	6966	G	A	MI.4146	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1063	355	G	S	Ggc/Agc	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	0	deleterious	-9,49	deleterious	-3,63	high_impact	4,92	neutral	0,63	damaging	0,25	deleterious	4,25	23,9	0,23	0,55	disease	0,81	disease	0,88	disease	0,73	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,73	0,9	2,92	6,68	P	0,67	P	0,73	polymorphism	0,73	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6966	6966	G	T	MI.4147	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1063	355	G	C	Ggc/Tgc	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	-0,02	deleterious	-12,37	deleterious	-5,44	high_impact	5,26	damaging	0,52	damaging	0,18	deleterious	4,22	23,9	0,12	0,55	disease	0,96	disease	0,93	disease	0,72	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,68	0,9	2,92	6,68	N	0,45	N	0,98	disease_causing	0,61	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6966	6966	G	C	MI.4148	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1063	355	G	R	Ggc/Cgc	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	-0,01	deleterious	-11,07	deleterious	-4,84	high_impact	4,57	damaging	0,56	damaging	0,16	deleterious	4,03	23,7	0,09	0,55	disease	0,8	disease	0,93	disease	0,82	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,12	0,66	0,9	2,92	6,68	N	0,47	N	0,95	polymorphism	0,56	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6967	6967	G	T	MI.4149	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1064	355	G	V	gGc/gTc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	-0,01	deleterious	-11,11	deleterious	-5,44	high_impact	4,92	damaging	0,54	damaging	0,22	deleterious	3,85	23,4	0,1	0,55	disease	0,91	disease	0,91	disease	0,75	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,59	0,9	2,92	6,68	P	0,58	P	0,93	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8720	8720	G	A	MI.415	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	194	65	G	E	gGa/gAa	2,44	0,99	0	probably_damaging	1	neutral	0,11	neutral	4,46	deleterious	-3,31	deleterious	-7,17	medium_impact	3,4	neutral	0,73	neutral	0,33	deleterious	3,84	23,4	0,35	0,65	disease	0,57	disease	0,87	disease	0,64	disease	0,73	5	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,22	medium_impact	1,82	0,38	0,9	49,12	8,59	N	0,43	N	1	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6967	6967	G	C	MI.4150	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1064	355	G	A	gGc/gCc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	0,08	deleterious	-6,65	deleterious	-3,63	high_impact	5,26	neutral	0,71	neutral	0,35	deleterious	3,17	22,7	0,26	0,55	disease	0,8	disease	0,79	disease	0,69	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,63	0,9	2,92	6,68	P	0,7	P	0,64	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6967	6967	G	A	MI.4151	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1064	355	G	D	gGc/gAc	9,15	1	0	probably_damaging	1	deleterious	0	neutral	-0,01	deleterious	-10,23	deleterious	-4,24	high_impact	5,26	damaging	0,49	damaging	0,19	deleterious	3,89	23,5	0,11	0,55	disease	0,82	disease	0,92	disease	0,81	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,76	0,5	0,9	2,92	6,68	P	0,62	P	0,97	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6969	6969	A	G	MI.4152	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1066	356	I	V	Att/Gtt	-10,28	0	0	benign	0	neutral	0,52	neutral	2,97	neutral	0,04	neutral	0,06	neutral_impact	-0,16	neutral	0,69	neutral	0,71	deleterious	0,72	8,94	0,59	0,65	neutral	0,2	neutral	0,09	neutral	0,25	neutral	0,26	5	neutral	0,47	deleterious	0,76	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,21	low_impact	-1,25	0,74	0,9	3,7	8,4	N	0,46	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6969	6969	A	C	MI.4153	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1066	356	I	L	Att/Ctt	-10,28	0	0	benign	0,08	deleterious	0,03	neutral	2,75	neutral	-0,67	neutral	-1,15	medium_impact	2,39	neutral	0,64	neutral	0,59	deleterious	2,84	21,6	0,41	0,55	neutral	0,26	disease	0,74	neutral	0,34	neutral	0,44	1	neutral	0,97	deleterious	0,48	deleterious	1	neutral	0,21	medium_impact	0,24	medium_impact	-0,65	medium_impact	1,11	0,77	0,9	3,7	8,4	N	0,46	N	0,61	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6969	6969	A	T	MI.4154	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1066	356	I	F	Att/Ttt	-10,28	0	0	possibly_damaging	0,58	deleterious	0	neutral	2,72	deleterious	-3,39	neutral	-2,37	high_impact	4,11	neutral	0,6	neutral	0,41	deleterious	3,94	23,5	0,29	0,55	disease	0,59	disease	0,88	disease	0,61	disease	0,74	5	deleterious	1	neutral	0,21	deleterious	5	deleterious	0,69	medium_impact	-0,89	low_impact	-1,48	high_impact	2,7	0,79	0,9	3,7	8,4	N	0,37	N	0,85	polymorphism	0,63	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6970	6970	T	C	MI.4155	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1067	356	I	T	aTt/aCt	8,69	1	0	possibly_damaging	0,56	deleterious	0	neutral	2,64	deleterious	-3,51	neutral	-2,31	high_impact	3,9	neutral	0,65	neutral	0,44	deleterious	3,47	23	0,4	0,55	disease	0,54	disease	0,75	disease	0,55	disease	0,67	3	deleterious	1	neutral	0,22	deleterious	5	deleterious	0,53	medium_impact	-0,86	low_impact	-1,48	high_impact	2,5	0,69	0,9	3,7	8,4	P	0,53	P	0,76	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6970	6970	T	A	MI.4156	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1067	356	I	N	aTt/aAt	8,69	1	0	probably_damaging	0,95	deleterious	0	neutral	2,59	deleterious	-4,97	deleterious	-3,84	high_impact	4,45	neutral	0,62	neutral	0,44	deleterious	4,46	24,2	0,2	0,55	disease	0,77	disease	0,91	disease	0,6	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,84	low_impact	-1,96	low_impact	-1,48	high_impact	3,01	0,58	0,9	3,7	8,4	P	0,5	N	0,94	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6970	6970	T	G	MI.4157	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1067	356	I	S	aTt/aGt	8,69	1	0	possibly_damaging	0,81	deleterious	0	neutral	2,66	deleterious	-4	deleterious	-3,24	high_impact	4,11	neutral	0,67	neutral	0,51	deleterious	4,37	24,1	0,2	0,55	disease	0,62	disease	0,9	disease	0,58	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	5	deleterious	0,73	low_impact	-1,35	low_impact	-1,48	high_impact	2,7	0,53	0,9	3,7	8,4	P	0,53	P	0,62	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6971	6971	T	A	MI.4158	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1068	356	I	M	atT/atA	7,53	1	0	possibly_damaging	0,81	deleterious	0	neutral	2,66	neutral	-2,65	neutral	-1,43	high_impact	3,56	neutral	0,67	neutral	0,6	deleterious	3,81	23,4	0,36	0,55	neutral	0,42	disease	0,73	neutral	0,49	disease	0,53	1	deleterious	1	neutral	0,1	deleterious	5	deleterious	0,6	low_impact	-1,35	low_impact	-1,48	high_impact	2,19	0,83	0,9	3,7	8,4	P	0,54	P	0,76	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6971	6971	T	G	MI.4159	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1068	356	I	M	atT/atG	7,53	1	0	possibly_damaging	0,81	deleterious	0	neutral	2,66	neutral	-2,65	neutral	-1,43	high_impact	3,56	neutral	0,67	neutral	0,6	deleterious	3,47	23	0,36	0,55	neutral	0,42	disease	0,73	neutral	0,49	disease	0,53	1	deleterious	1	neutral	0,1	deleterious	5	deleterious	0,6	low_impact	-1,35	low_impact	-1,48	high_impact	2,19	0,83	0,9	3,7	8,4	P	0,53	P	0,76	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8720	8720	G	T	MI.416	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	194	65	G	V	gGa/gTa	2,44	0,99	0	probably_damaging	1	neutral	0,2	neutral	4,33	deleterious	-3,53	deleterious	-8,05	medium_impact	3,2	damaging	0,59	neutral	0,32	deleterious	3,68	23,3	0,33	0,65	disease	0,73	disease	0,86	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	-0,05	medium_impact	1,65	0,45	0,9	49,12	8,59	N	0,42	N	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6972	6972	G	A	MI.4160	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1069	357	V	M	Gta/Ata	-3,34	0	0	possibly_damaging	0,82	neutral	0,21	neutral	2,88	neutral	0,68	neutral	-1,08	low_impact	1,32	neutral	0,66	neutral	0,6	deleterious	2,25	17,85	0,47	0,55	neutral	0,25	disease	0,65	neutral	0,33	neutral	0,45	1	neutral	0,89	neutral	0,2	neutral	-3	deleterious	0,64	low_impact	-1,38	medium_impact	-0,13	medium_impact	0,12	0,97	1	12,09	28,1	N	0,43	N	0,74	disease_causing	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6972	6972	G	T	MI.4161	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1069	357	V	L	Gta/Tta	-3,34	0	0	benign	0,03	neutral	0,06	neutral	3	neutral	1,37	neutral	-1,03	medium_impact	2,47	neutral	0,65	neutral	0,57	neutral	1,77	14,83	0,37	0,55	neutral	0,29	disease	0,78	neutral	0,37	disease	0,56	1	neutral	0,94	deleterious	0,52	neutral	-3	neutral	0,23	medium_impact	0,66	medium_impact	-0,47	medium_impact	1,18	0,77	0,9	12,09	28,1	N	0,46	N	0,49	disease_causing	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6972	6972	G	C	MI.4162	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1069	357	V	L	Gta/Cta	-3,34	0	0	benign	0,03	neutral	0,06	neutral	3	neutral	1,37	neutral	-1,03	medium_impact	2,47	neutral	0,65	neutral	0,57	neutral	1,62	13,95	0,37	0,55	neutral	0,29	disease	0,78	neutral	0,37	disease	0,56	1	neutral	0,94	deleterious	0,52	neutral	-3	neutral	0,23	medium_impact	0,66	medium_impact	-0,47	medium_impact	1,18	0,77	0,9	12,09	28,1	N	0,46	N	0,49	disease_causing	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6973	6973	T	C	MI.4163	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1070	357	V	A	gTa/gCa	3,6	1	0	possibly_damaging	0,54	deleterious	0	neutral	2,78	neutral	-0,33	neutral	-2,18	medium_impact	3	neutral	0,65	neutral	0,62	deleterious	1,95	15,92	0,29	0,55	neutral	0,39	disease	0,67	neutral	0,42	neutral	0,49	0	deleterious	1	neutral	0,23	deleterious	4	deleterious	0,52	medium_impact	-0,82	low_impact	-1,48	medium_impact	1,67	0,64	0,9	12,09	28,1	N	0,48	N	0,66	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6973	6973	T	A	MI.4164	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1070	357	V	E	gTa/gAa	3,6	1	0	possibly_damaging	0,86	deleterious	0	neutral	2,69	neutral	-2,98	deleterious	-3,31	high_impact	4,28	neutral	0,6	neutral	0,5	deleterious	4,48	24,2	0,09	0,55	disease	0,69	disease	0,93	disease	0,72	disease	0,81	6	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,87	low_impact	-1,5	low_impact	-1,48	high_impact	2,85	0,61	0,9	12,09	28,1	P	0,54	P	0,92	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6973	6973	T	G	MI.4165	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1070	357	V	G	gTa/gGa	3,6	1	0	possibly_damaging	0,9	deleterious	0	neutral	2,69	neutral	-2,75	deleterious	-3,9	high_impact	4,28	neutral	0,61	neutral	0,61	deleterious	3,69	23,3	0,13	0,55	disease	0,66	disease	0,85	disease	0,6	disease	0,73	5	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,8	low_impact	-1,65	low_impact	-1,48	high_impact	2,85	0,49	0,9	12,09	28,1	N	0,48	N	0,75	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6975	6975	T	A	MI.4166	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1072	358	L	M	Tta/Ata	-13,29	0	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-3,47	neutral	-1,17	high_impact	4,68	damaging	0,56	damaging	0,07	deleterious	3,63	23,2	0,32	0,55	disease	0,67	disease	0,71	disease	0,61	disease	0,57	1	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,22	0,81	0,9	1,56	6,7	N	0,47	N	0,59	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6975	6975	T	G	MI.4167	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1072	358	L	V	Tta/Gta	-13,29	0	0	probably_damaging	0,99	deleterious	0	neutral	2,61	neutral	-2,75	neutral	-1,74	high_impact	4,13	damaging	0,5	damaging	0,07	deleterious	3,48	23,1	0,34	0,55	neutral	0,42	disease	0,74	disease	0,62	disease	0,58	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,64	low_impact	-1,48	high_impact	2,71	0,66	0,9	1,56	6,7	N	0,31	N	0,66	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6976	6976	T	C	MI.4168	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1073	358	L	S	tTa/tCa	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-3,37	deleterious	-3,55	high_impact	4,68	damaging	0,51	damaging	0,08	deleterious	3,88	23,5	0,24	0,55	disease	0,62	disease	0,88	disease	0,68	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,22	0,63	0,9	1,56	6,7	N	0,5	N	0,73	polymorphism	1	0,45	.	.	.	.	.	.	COSM1331632	.	.	.	.	.	.	.	.
chrM	6976	6976	T	G	MI.4169	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1073	358	L	W	tTa/tGa	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-6,4	deleterious	-3,56	high_impact	4,88	damaging	0,47	damaging	0,05	deleterious	3,87	23,5	0,11	0,55	disease	0,89	disease	0,83	disease	0,66	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,41	0,55	0,9	1,56	6,7	P	0,56	P	0,92	polymorphism	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8720	8720	G	C	MI.417	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	194	65	G	A	gGa/gCa	2,44	0,99	0	probably_damaging	1	neutral	0,26	neutral	4,36	neutral	-2,39	deleterious	-5,29	medium_impact	2,15	neutral	0,66	neutral	0,41	deleterious	2,9	21,8	0,3	0,65	disease	0,64	disease	0,65	neutral	0,36	neutral	0,48	0	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	0,04	medium_impact	0,75	0,57	0,9	49,12	8,59	N	0,43	N	0,79	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6977	6977	A	T	MI.4170	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1074	358	L	F	ttA/ttT	5,91	0,9	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-3,97	neutral	-2,37	high_impact	4,88	damaging	0,49	damaging	0,04	deleterious	3,66	23,2	0,34	0,55	disease	0,68	disease	0,83	disease	0,63	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,41	0,66	0,9	1,56	6,7	P	0,66	P	0,87	polymorphism	0,9	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6977	6977	A	C	MI.4171	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1074	358	L	F	ttA/ttC	5,91	0,9	0	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-3,97	neutral	-2,37	high_impact	4,88	damaging	0,49	damaging	0,04	deleterious	3,58	23,2	0,34	0,55	disease	0,68	disease	0,83	disease	0,63	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,41	0,66	0,9	1,56	6,7	P	0,66	P	0,87	polymorphism	0,9	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6978	6978	G	A	MI.4172	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1075	359	A	T	Gca/Aca	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,57	neutral	-2,52	neutral	-1,55	high_impact	4,37	neutral	0,64	damaging	0,19	deleterious	4,34	24	0,43	0,55	disease	0,61	disease	0,79	disease	0,53	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,94	0,76	0,9	5,85	39,81	N	0,36	N	0,38	polymorphism	0,97	0,13	rs28451817	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6978	6978	G	C	MI.4173	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1075	359	A	P	Gca/Cca	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,53	deleterious	-3,28	neutral	-2,31	high_impact	4,37	neutral	0,62	damaging	0,11	deleterious	3,93	23,5	0,12	0,55	disease	0,78	disease	0,91	disease	0,54	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	2,94	0,83	0,9	5,85	39,81	N	0,38	N	0,59	polymorphism	0,9	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6978	6978	G	T	MI.4174	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1075	359	A	S	Gca/Tca	-1,26	0	0	probably_damaging	1	neutral	0,66	neutral	2,79	neutral	-0,85	neutral	-0,54	neutral_impact	0,39	neutral	0,63	neutral	0,89	deleterious	2,34	18,41	0,34	0,55	neutral	0,35	neutral	0,34	neutral	0,28	neutral	0,42	2	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,75	low_impact	-3,58	medium_impact	0,35	medium_impact	-0,74	0,9	0,95	5,85	39,81	N	0,36	N	0,09	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6979	6979	C	A	MI.4175	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1076	359	A	E	gCa/gAa	4,06	1	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-3,93	neutral	-2,12	high_impact	4,71	neutral	0,64	damaging	0,12	deleterious	4,62	24,5	0,11	0,55	neutral	0,29	disease	0,92	disease	0,72	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,25	0,75	0,9	5,85	39,81	P	0,66	P	0,67	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6979	6979	C	T	MI.4176	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1076	359	A	V	gCa/gTa	4,06	1	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-5,03	neutral	-2,15	high_impact	4,71	damaging	0,6	damaging	0,12	deleterious	4,51	24,3	0,36	0,55	disease	0,73	disease	0,85	disease	0,62	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,25	0,76	0,9	5,85	39,81	P	0,68	P	0,56	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6979	6979	C	G	MI.4177	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1076	359	A	G	gCa/gGa	4,06	1	0	probably_damaging	1	deleterious	0,04	neutral	2,6	neutral	-2,15	neutral	-1,53	medium_impact	2,98	neutral	0,64	damaging	0,16	deleterious	3,93	23,5	0,23	0,55	neutral	0,32	disease	0,76	disease	0,52	disease	0,57	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,74	low_impact	-3,58	medium_impact	-0,58	medium_impact	1,65	0,83	0,9	5,85	39,81	N	0,42	N	0,34	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6981	6981	A	C	MI.4178	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1078	360	N	H	Aac/Cac	-8,2	0	0	probably_damaging	1	deleterious	0	neutral	2,85	neutral	-2,84	deleterious	-2,96	high_impact	4,13	damaging	0,58	damaging	0,05	deleterious	3,17	22,7	0,48	0,55	neutral	0,42	disease	0,88	disease	0,7	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,42	0,9	1,75	7,28	N	0,32	N	0,83	disease_causing	0,74	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6981	6981	A	G	MI.4179	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1078	360	N	D	Aac/Gac	-8,2	0	0	probably_damaging	0,99	deleterious	0	neutral	2,86	neutral	-1,05	deleterious	-2,96	high_impact	4,3	damaging	0,48	damaging	0,07	deleterious	3,97	23,6	0,54	0,6	neutral	0,48	disease	0,86	disease	0,76	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	high_impact	2,87	0,46	0,9	1,75	7,28	N	0,46	N	0,92	disease_causing	0,58	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8722	8722	C	T	MI.418	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	196	66	R	W	Cga/Tga	-3,11	0	0	possibly_damaging	0,86	neutral	0,15	neutral	4,28	deleterious	-5,25	deleterious	-3,81	low_impact	1,07	neutral	0,87	damaging	0,25	deleterious	5,05	25,2	0,36	0,65	disease	0,94	disease	0,69	disease	0,64	disease	0,85	7	neutral	0,93	neutral	0,15	neutral	-3	deleterious	0,76	low_impact	-1,5	medium_impact	-0,13	medium_impact	-0,18	0,87	0,9	18,14	13,71	N	0,33	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6981	6981	A	T	MI.4180	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1078	360	N	Y	Aac/Tac	-8,2	0	0	probably_damaging	1	deleterious	0	neutral	2,86	deleterious	-3,54	deleterious	-4,74	high_impact	5,11	damaging	0,54	damaging	0,06	deleterious	3,87	23,5	0,33	0,55	neutral	0,24	disease	0,92	disease	0,74	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,32	0,9	1,75	7,28	P	0,58	P	0,93	disease_causing	0,92	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6982	6982	A	G	MI.4181	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1079	360	N	S	aAc/aGc	8,69	1	0	probably_damaging	0,98	neutral	0,07	neutral	2,95	neutral	0,28	deleterious	-2,96	medium_impact	2,44	damaging	0,56	damaging	0,07	deleterious	3,07	22,4	0,49	0,55	neutral	0,18	disease	0,85	neutral	0,45	neutral	0,42	2	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,76	low_impact	-2,35	medium_impact	-0,43	medium_impact	1,15	0,27	0,9	1,75	7,28	N	0,46	N	0,79	disease_causing	1	0,08	rs201872766	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6982	6982	A	T	MI.4182	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1079	360	N	I	aAc/aTc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,98	neutral	-1,76	deleterious	-5,34	high_impact	4,3	damaging	0,59	damaging	0,06	deleterious	3,87	23,5	0,32	0,55	neutral	0,34	disease	0,93	disease	0,69	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,87	0,26	0,9	1,75	7,28	N	0,48	N	0,98	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6982	6982	A	C	MI.4183	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1079	360	N	T	aAc/aCc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,91	neutral	-1,32	deleterious	-3,56	high_impact	4,07	damaging	0,59	damaging	0,07	deleterious	3,39	23	0,47	0,55	neutral	0,33	disease	0,87	disease	0,69	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,66	0,43	0,9	1,75	7,28	N	0,46	N	0,59	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6983	6983	C	A	MI.4184	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1080	360	N	K	aaC/aaA	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,85	neutral	-0,85	deleterious	-3,56	high_impact	5,11	damaging	0,51	damaging	0,06	deleterious	4,54	24,3	0,55	0,6	neutral	0,35	disease	0,9	disease	0,77	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,47	0,9	1,75	7,28	P	0,71	P	0,92	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6983	6983	C	G	MI.4185	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1080	360	N	K	aaC/aaG	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,85	neutral	-0,85	deleterious	-3,56	high_impact	5,11	damaging	0,51	damaging	0,06	deleterious	4,14	23,8	0,55	0,6	neutral	0,35	disease	0,9	disease	0,77	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,47	0,9	1,75	7,28	P	0,7	P	0,92	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6984	6984	T	C	MI.4186	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1081	361	S	P	Tca/Cca	-1,03	0,01	0	probably_damaging	1	deleterious	0	neutral	2,95	neutral	-0,41	deleterious	-2,88	medium_impact	2,96	damaging	0,29	damaging	0,07	deleterious	4,16	23,8	0,2	0,55	neutral	0,49	disease	0,87	disease	0,56	disease	0,68	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	medium_impact	1,63	0,6	0,9	1,56	6,95	P	0,69	P	0,91	disease_causing	0,99	0,08	.	.	.	.	.	.	COSM1155667	.	.	.	.	.	.	.	.
chrM	6984	6984	T	A	MI.4187	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1081	361	S	T	Tca/Aca	-1,03	0,01	0	probably_damaging	0,99	deleterious	0	neutral	2,87	neutral	-0,96	neutral	-1,69	high_impact	4,11	damaging	0,47	damaging	0,06	deleterious	4,07	23,7	0,33	0,55	neutral	0,39	disease	0,69	neutral	0,42	neutral	0,49	0	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,72	low_impact	-2,64	low_impact	-1,48	high_impact	2,7	0,64	0,9	1,56	6,95	N	0,39	N	0,43	disease_causing	0,94	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6984	6984	T	G	MI.4188	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1081	361	S	A	Tca/Gca	-1,03	0,01	0	probably_damaging	0,99	neutral	0,15	neutral	2,97	neutral	0,58	neutral	-1,66	medium_impact	2,36	damaging	0,53	damaging	0,15	deleterious	3,83	23,4	0,41	0,55	neutral	0,22	neutral	0,4	neutral	0,21	neutral	0,39	2	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,7	low_impact	-2,64	medium_impact	-0,23	medium_impact	1,08	0,59	0,9	1,56	6,95	N	0,45	N	0,35	disease_causing	0,81	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6985	6985	C	G	MI.4189	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1082	361	S	W	tCa/tGa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,83	deleterious	-3,42	deleterious	-3,98	high_impact	5	damaging	0,44	damaging	0,04	deleterious	4,49	24,3	0,19	0,55	disease	0,83	disease	0,9	disease	0,67	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,43	0,9	1,56	6,95	P	0,7	P	0,94	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8722	8722	C	G	MI.419	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	196	66	R	G	Cga/Gga	-3,11	0	0	benign	0,28	neutral	0,34	neutral	4,38	neutral	-2,38	deleterious	-3,54	neutral_impact	-0,51	neutral	0,84	neutral	0,36	deleterious	2,31	18,26	0,39	0,65	neutral	0,32	neutral	0,47	disease	0,61	neutral	0,49	0	neutral	0,59	deleterious	0,53	neutral	-6	neutral	0,4	medium_impact	-0,37	medium_impact	0,13	low_impact	-1,54	0,46	0,9	18,14	13,71	N	0,29	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6985	6985	C	T	MI.4190	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1082	361	S	L	tCa/tTa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,92	neutral	-0,22	deleterious	-3,38	high_impact	4,2	damaging	0,5	damaging	0,03	deleterious	4,81	24,8	0,23	0,55	neutral	0,32	disease	0,87	disease	0,6	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,78	0,79	0,9	1,56	6,95	P	0,52	P	0,9	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6987	6987	T	A	MI.4191	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1084	362	S	T	Tca/Aca	-13,75	0	0	probably_damaging	0,95	deleterious	0	neutral	2,72	neutral	-0,97	neutral	-1,63	medium_impact	3,46	damaging	0,49	damaging	0,17	deleterious	3,91	23,5	0,26	0,55	neutral	0,38	disease	0,67	neutral	0,4	neutral	0,47	1	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,74	low_impact	-1,96	low_impact	-1,48	high_impact	2,1	0,63	0,9	2,92	6,73	N	0,41	N	0,43	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6987	6987	T	G	MI.4192	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1084	362	S	A	Tca/Gca	-13,75	0	0	probably_damaging	0,97	deleterious	0,01	neutral	2,79	neutral	-0,45	neutral	-1,67	medium_impact	2,6	damaging	0,59	damaging	0,19	deleterious	3,81	23,4	0,34	0,55	neutral	0,19	disease	0,56	neutral	0,26	neutral	0,4	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,66	low_impact	-2,18	medium_impact	-0,92	medium_impact	1,3	0,56	0,9	2,92	6,73	N	0,36	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6987	6987	T	C	MI.4193	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1084	362	S	P	Tca/Cca	-13,75	0	0	probably_damaging	0,99	deleterious	0	neutral	2,84	neutral	-0,29	deleterious	-2,87	medium_impact	2,5	damaging	0,38	damaging	0,22	deleterious	4,12	23,8	0,16	0,55	neutral	0,23	disease	0,86	neutral	0,4	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,79	low_impact	-2,64	low_impact	-1,48	medium_impact	1,21	0,55	0,9	2,92	6,73	N	0,44	N	0,91	polymorphism	0,93	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6988	6988	C	G	MI.4194	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1085	362	S	W	tCa/tGa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,65	deleterious	-5,52	deleterious	-4,04	high_impact	5	damaging	0,49	damaging	0,15	deleterious	4,4	24,1	0,18	0,55	disease	0,87	disease	0,9	disease	0,63	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,39	0,9	2,92	6,73	P	0,67	P	0,94	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6988	6988	C	T	MI.4195	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1085	362	S	L	tCa/tTa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-2,16	deleterious	-3,43	high_impact	5	damaging	0,5	damaging	0,13	deleterious	4,68	24,6	0,21	0,55	neutral	0,5	disease	0,88	disease	0,56	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,76	0,9	2,92	6,73	P	0,7	P	0,9	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6990	6990	C	A	MI.4196	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1087	363	L	M	Cta/Ata	-8,66	0	0	probably_damaging	1	deleterious	0,02	neutral	2,74	neutral	-2,78	neutral	-0,84	medium_impact	3,06	damaging	0,58	damaging	0,06	deleterious	3,88	23,5	0,34	0,55	neutral	0,46	disease	0,5	neutral	0,21	neutral	0,47	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,73	0,86	0,9	2,92	6,66	N	0,33	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6990	6990	C	G	MI.4197	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1087	363	L	V	Cta/Gta	-8,66	0	0	probably_damaging	0,97	neutral	0,08	neutral	3,09	neutral	0,4	neutral	-0,52	medium_impact	2,02	damaging	0,55	damaging	0,08	deleterious	2,44	19,07	0,35	0,55	neutral	0,23	neutral	0,48	neutral	0,21	neutral	0,44	1	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,7	low_impact	-2,18	medium_impact	-0,4	medium_impact	0,77	0,62	0,9	2,92	6,66	N	0,37	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6991	6991	T	C	MI.4198	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1088	363	L	P	cTa/cCa	-0,57	0	0,01	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-4,17	deleterious	-3,47	high_impact	4,47	damaging	0,49	damaging	0,03	deleterious	4,07	23,7	0,16	0,55	neutral	0,31	disease	0,88	disease	0,56	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,03	0,57	0,9	2,92	6,66	N	0,37	N	0,83	disease_causing	1	0,32	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	6991	6991	T	G	MI.4199	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1088	363	L	R	cTa/cGa	-0,57	0	0,01	probably_damaging	1	deleterious	0	neutral	2,72	deleterious	-3,69	deleterious	-3,21	high_impact	4,47	damaging	0,52	damaging	0,03	deleterious	4,32	24	0,15	0,55	disease	0,67	disease	0,89	disease	0,7	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,03	0,49	0,9	2,92	6,66	N	0,41	N	0,9	polymorphism	0,98	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8544	8544	C	G	MI.42	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	18	6	F	L	ttC/ttG	5,91	1	0	probably_damaging	0,92	deleterious	0,01	neutral	4,01	neutral	-0,1	deleterious	-5,08	medium_impact	3,32	damaging	0,56	neutral	0,6	deleterious	4,3	24	0,46	0,65	disease	0,61	disease	0,63	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,05	deleterious	5	deleterious	0,73	low_impact	-1,76	medium_impact	-0,84	medium_impact	1,75	0,33	0,9	39,82	8,43	P	0,59	P	0,89	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8723	8723	G	C	MI.420	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	197	66	R	P	cGa/cCa	1,75	0,01	0,02	possibly_damaging	0,56	neutral	0,31	neutral	4,37	deleterious	-3,16	deleterious	-3,37	neutral_impact	0,52	neutral	0,75	damaging	0,27	deleterious	3,86	23,5	0,27	0,65	neutral	0,47	disease	0,78	disease	0,63	disease	0,73	5	neutral	0,69	neutral	0,38	neutral	-3	deleterious	0,67	medium_impact	-0,86	medium_impact	0,1	medium_impact	-0,65	0,51	0,9	18,14	13,71	N	0,29	N	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6991	6991	T	A	MI.4200	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1088	363	L	Q	cTa/cAa	-0,57	0	0,01	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-4,09	deleterious	-3,17	high_impact	4,47	damaging	0,53	damaging	0,04	deleterious	4,47	24,2	0,16	0,55	disease	0,69	disease	0,76	disease	0,57	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,03	0,71	0,9	2,92	6,66	N	0,38	N	0,82	polymorphism	0,98	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6993	6993	G	T	MI.4201	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1090	364	D	Y	Gac/Tac	0,13	0,96	0	probably_damaging	0,99	deleterious	0	neutral	2,29	deleterious	-8,09	deleterious	-5,26	high_impact	4,86	damaging	0,59	damaging	0,09	deleterious	4,02	23,6	0,18	0,55	disease	0,94	disease	0,95	disease	0,79	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,93	low_impact	-2,64	low_impact	-1,48	high_impact	3,39	0,57	0,9	4,29	7,75	P	0,59	P	0,94	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6993	6993	G	A	MI.4202	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1090	364	D	N	Gac/Aac	0,13	0,96	0	benign	0,08	deleterious	0	neutral	2,81	neutral	-2,01	deleterious	-2,91	high_impact	3,68	damaging	0,44	damaging	0,11	deleterious	4,31	24	0,52	0,6	neutral	0,43	disease	0,85	disease	0,62	disease	0,63	3	deleterious	1	neutral	0,46	deleterious	2	neutral	0,32	medium_impact	0,24	low_impact	-1,48	high_impact	2,3	0,81	0,9	4,29	7,75	N	0,49	N	0,89	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6993	6993	G	C	MI.4203	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1090	364	D	H	Gac/Cac	0,13	0,96	0	probably_damaging	0,97	deleterious	0	neutral	2,3	deleterious	-6,81	deleterious	-4,08	high_impact	5,21	neutral	0,62	damaging	0,08	deleterious	3,73	23,3	0,25	0,55	disease	0,87	disease	0,9	disease	0,82	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,9	low_impact	-2,18	low_impact	-1,48	high_impact	3,71	0,65	0,9	4,29	7,75	P	0,64	P	0,97	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6994	6994	A	G	MI.4204	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1091	364	D	G	gAc/gGc	9,15	1	0	possibly_damaging	0,79	deleterious	0	neutral	2,32	deleterious	-5,05	deleterious	-4,09	high_impact	4,51	damaging	0,57	damaging	0,11	deleterious	4,07	23,7	0,24	0,55	neutral	0,38	disease	0,91	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	5	deleterious	0,66	low_impact	-1,3	low_impact	-1,48	high_impact	3,07	0,63	0,9	4,29	7,75	P	0,51	P	0,85	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6994	6994	A	C	MI.4205	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1091	364	D	A	gAc/gCc	9,15	1	0	possibly_damaging	0,73	deleterious	0	neutral	2,31	deleterious	-5,75	deleterious	-4,67	high_impact	5,21	neutral	0,71	damaging	0,12	deleterious	3,79	23,4	0,23	0,55	disease	0,77	disease	0,88	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,14	deleterious	5	deleterious	0,78	low_impact	-1,16	low_impact	-1,48	high_impact	3,71	0,62	0,9	4,29	7,75	P	0,68	P	0,85	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6994	6994	A	T	MI.4206	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1091	364	D	V	gAc/gTc	9,15	1	0	probably_damaging	0,96	deleterious	0	neutral	2,29	deleterious	-7,47	deleterious	-5,26	high_impact	5,21	damaging	0,47	damaging	0,11	deleterious	3,84	23,4	0,18	0,55	disease	0,91	disease	0,95	disease	0,76	disease	0,8	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,9	low_impact	-2,06	low_impact	-1,48	high_impact	3,71	0,42	0,9	4,29	7,75	P	0,62	P	0,93	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6995	6995	C	G	MI.4207	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1092	364	D	E	gaC/gaG	6,84	1	0	benign	0,36	deleterious	0	neutral	2,34	deleterious	-3,88	neutral	-2,33	high_impact	4,66	damaging	0,48	damaging	0,12	deleterious	4	23,6	0,45	0,55	disease	0,56	disease	0,88	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,52	medium_impact	-0,52	low_impact	-1,48	high_impact	3,2	0,67	0,9	4,29	7,75	P	0,55	P	0,65	disease_causing	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6995	6995	C	A	MI.4208	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1092	364	D	E	gaC/gaA	6,84	1	0	benign	0,36	deleterious	0	neutral	2,34	deleterious	-3,88	neutral	-2,33	high_impact	4,66	damaging	0,48	damaging	0,12	deleterious	4,33	24	0,45	0,55	disease	0,56	disease	0,88	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,52	medium_impact	-0,52	low_impact	-1,48	high_impact	3,2	0,67	0,9	4,29	7,75	P	0,56	P	0,65	disease_causing	1	0,53	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6996	6996	A	C	MI.4209	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1093	365	I	L	Atc/Ctc	-3,8	0	0	probably_damaging	0,96	neutral	0,07	neutral	2,8	neutral	-0,03	neutral	-1,1	medium_impact	2,1	neutral	0,66	damaging	0,13	deleterious	3,81	23,4	0,4	0,55	neutral	0,22	disease	0,73	neutral	0,21	neutral	0,4	2	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,56	low_impact	-2,06	medium_impact	-0,43	medium_impact	0,84	0,77	0,9	5,07	9,12	N	0,35	N	0,61	disease_causing	0,96	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8723	8723	G	T	MI.421	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	197	66	R	L	cGa/cTa	1,75	0,01	0,02	benign	0,22	neutral	0,57	neutral	4,31	neutral	-2,05	deleterious	-3,61	neutral_impact	-0,33	neutral	0,94	neutral	0,69	deleterious	2,35	18,47	0,36	0,65	disease	0,57	disease	0,63	disease	0,53	disease	0,59	2	neutral	0,32	deleterious	0,68	neutral	-6	deleterious	0,44	medium_impact	-0,23	medium_impact	0,36	low_impact	-1,38	0,57	0,9	18,14	13,71	N	0,26	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6996	6996	A	T	MI.4210	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1093	365	I	F	Atc/Ttc	-3,8	0	0	probably_damaging	0,99	deleterious	0	neutral	2,72	neutral	-1,03	neutral	-2,22	medium_impact	2,84	neutral	0,63	damaging	0,1	deleterious	3,76	23,3	0,33	0,55	neutral	0,4	disease	0,86	disease	0,56	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-2,64	low_impact	-1,48	medium_impact	1,52	0,73	0,9	5,07	9,12	N	0,26	N	0,85	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6996	6996	A	G	MI.4211	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1093	365	I	V	Atc/Gtc	-3,8	0	0	probably_damaging	0,91	neutral	0,24	neutral	2,85	neutral	0,31	neutral	-0,41	low_impact	1,84	neutral	0,72	neutral	0,69	deleterious	1,88	15,48	0,59	0,65	neutral	0,25	neutral	0,31	neutral	0,21	neutral	0,41	2	neutral	0,93	neutral	0,17	neutral	-2	deleterious	0,53	low_impact	-1,7	medium_impact	-0,09	medium_impact	0,6	0,7	0,9	5,07	9,12	N	0,49	N	0,23	disease_causing	0,9	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6997	6997	T	A	MI.4212	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1094	365	I	N	aTc/aAc	4,76	1	0	probably_damaging	1	deleterious	0	neutral	2,66	neutral	-2,84	deleterious	-3,77	high_impact	3,93	neutral	0,65	damaging	0,13	deleterious	4,61	24,4	0,22	0,55	disease	0,68	disease	0,87	disease	0,58	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,53	0,65	0,9	5,07	9,12	N	0,43	N	0,94	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6997	6997	T	C	MI.4213	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1094	365	I	T	aTc/aCc	4,76	1	0	probably_damaging	1	deleterious	0,03	neutral	2,75	neutral	-0,61	deleterious	-2,51	medium_impact	2,37	neutral	0,64	damaging	0,16	deleterious	3,51	23,1	0,29	0,55	neutral	0,46	disease	0,75	neutral	0,3	neutral	0,44	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-3,58	medium_impact	-0,65	medium_impact	1,09	0,74	0,9	5,07	9,12	N	0,42	N	0,76	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6997	6997	T	G	MI.4214	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1094	365	I	S	aTc/aGc	4,76	1	0	probably_damaging	1	neutral	0,07	neutral	2,69	neutral	-1,8	deleterious	-3,2	high_impact	3,67	neutral	0,68	damaging	0,16	deleterious	4,45	24,2	0,26	0,55	disease	0,51	disease	0,9	disease	0,58	disease	0,7	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,85	low_impact	-3,58	medium_impact	-0,43	high_impact	2,29	0,59	0,9	5,07	9,12	N	0,47	N	0,62	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6998	6998	C	A	MI.4215	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1095	365	I	M	atC/atA	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	2,71	neutral	-1,3	neutral	-1,58	medium_impact	3,2	neutral	0,66	damaging	0,15	deleterious	4	23,6	0,35	0,55	neutral	0,46	disease	0,64	neutral	0,36	neutral	0,42	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,86	0,81	0,9	5,07	9,12	P	0,48	N	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6998	6998	C	G	MI.4216	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1095	365	I	M	atC/atG	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	2,71	neutral	-1,3	neutral	-1,58	medium_impact	3,2	neutral	0,66	damaging	0,15	deleterious	3,49	23,1	0,35	0,55	neutral	0,46	disease	0,64	neutral	0,36	neutral	0,42	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,86	0,81	0,9	5,07	9,12	P	0,48	N	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6999	6999	G	T	MI.4217	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1096	366	V	L	Gta/Tta	-2,42	0	0	benign	0,07	neutral	0,2	neutral	2,76	neutral	-0,5	neutral	-0,8	low_impact	1,46	neutral	0,73	damaging	0,17	deleterious	0,81	9,52	0,3	0,55	neutral	0,27	disease	0,6	neutral	0,27	neutral	0,46	1	neutral	0,78	deleterious	0,57	neutral	-6	neutral	0,18	medium_impact	0,3	medium_impact	-0,14	medium_impact	0,25	0,72	0,9	8,19	18,05	N	0,4	N	0,55	polymorphism	0,9	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6999	6999	G	C	MI.4218	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1096	366	V	L	Gta/Cta	-2,42	0	0	benign	0,07	neutral	0,2	neutral	2,76	neutral	-0,5	neutral	-0,8	low_impact	1,46	neutral	0,73	damaging	0,17	deleterious	0,66	8,53	0,3	0,55	neutral	0,27	disease	0,6	neutral	0,27	neutral	0,46	1	neutral	0,78	deleterious	0,57	neutral	-6	neutral	0,18	medium_impact	0,3	medium_impact	-0,14	medium_impact	0,25	0,72	0,9	8,19	18,05	N	0,4	N	0,55	polymorphism	0,9	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	6999	6999	G	A	MI.4219	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1096	366	V	M	Gta/Ata	-2,42	0	0	benign	0,21	neutral	0,09	neutral	2,7	neutral	-1,35	neutral	-0,94	low_impact	1,48	neutral	0,65	damaging	0,27	deleterious	0,51	7,48	0,29	0,55	neutral	0,46	neutral	0,37	neutral	0,25	neutral	0,47	1	neutral	0,9	neutral	0,44	neutral	-6	neutral	0,27	medium_impact	-0,22	medium_impact	-0,37	medium_impact	0,27	0,73	0,9	8,19	18,05	N	0,42	N	0,82	polymorphism	0,88	0,03	rs879099364	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8723	8723	G	A	MI.422	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	197	66	R	Q	cGa/cAa	1,75	0,01	0,02	benign	0,01	neutral	0,52	neutral	4,4	neutral	-0,97	neutral	-0,52	neutral_impact	-1,06	neutral	0,91	neutral	0,94	deleterious	0,79	9,41	0,39	0,65	neutral	0,31	neutral	0,27	neutral	0,32	neutral	0,43	1	neutral	0,46	deleterious	0,76	neutral	-6	neutral	0,16	medium_impact	1,14	medium_impact	0,31	low_impact	-2,01	0,81	0,9	18,14	13,71	N	0,36	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7000	7000	T	A	MI.4220	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1097	366	V	E	gTa/gAa	1,52	0,93	0	possibly_damaging	0,85	deleterious	0	neutral	2,66	neutral	-2,36	deleterious	-2,96	medium_impact	3,28	neutral	0,67	damaging	0,18	deleterious	4,67	24,5	0,1	0,55	neutral	0,41	disease	0,86	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,08	deleterious	4	deleterious	0,77	low_impact	-1,47	low_impact	-1,48	medium_impact	1,93	0,48	0,9	8,19	18,05	N	0,34	N	0,84	disease_causing	0,95	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7000	7000	T	G	MI.4221	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1097	366	V	G	gTa/gGa	1,52	0,93	0	probably_damaging	0,93	deleterious	0	neutral	2,65	neutral	-2,81	deleterious	-3,48	medium_impact	3,08	neutral	0,68	damaging	0,19	deleterious	3,9	23,5	0,16	0,55	neutral	0,42	disease	0,73	disease	0,6	disease	0,7	4	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,72	low_impact	-1,81	low_impact	-1,48	medium_impact	1,75	0,46	0,9	8,19	18,05	N	0,33	N	0,71	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7000	7000	T	C	MI.4222	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1097	366	V	A	gTa/gCa	1,52	0,93	0	possibly_damaging	0,7	neutral	0,23	neutral	2,72	neutral	-0,93	neutral	-1,82	low_impact	0,88	neutral	0,66	neutral	0,4	deleterious	2,01	16,26	0,25	0,55	neutral	0,21	neutral	0,28	neutral	0,3	neutral	0,44	1	neutral	0,82	neutral	0,27	neutral	-3	deleterious	0,47	low_impact	-1,1	medium_impact	-0,1	medium_impact	-0,29	0,57	0,9	8,19	18,05	N	0,44	N	0,47	polymorphism	0,5	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7002	7002	C	A	MI.4223	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1099	367	L	M	Cta/Ata	-12,37	0	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-3,11	neutral	-1,01	medium_impact	2,87	damaging	0,49	damaging	0,08	deleterious	3,76	23,3	0,33	0,55	neutral	0,41	disease	0,55	neutral	0,32	neutral	0,21	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	medium_impact	1,55	0,7	0,9	NA	NA	N	0,34	N	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7002	7002	C	G	MI.4224	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1099	367	L	V	Cta/Gta	-12,37	0	0	probably_damaging	0,98	deleterious	0	neutral	2,79	neutral	-0,32	neutral	-1,65	medium_impact	3,12	damaging	0,5	damaging	0,04	deleterious	3,52	23,1	0,28	0,55	neutral	0,19	disease	0,67	disease	0,63	disease	0,56	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,73	low_impact	-2,35	low_impact	-1,48	medium_impact	1,78	0,56	0,9	NA	NA	N	0,31	N	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7003	7003	T	C	MI.4225	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1100	367	L	P	cTa/cCa	0,36	0,02	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-4,84	deleterious	-3,91	high_impact	4,29	damaging	0,36	damaging	0,05	deleterious	4,07	23,7	0,1	0,55	disease	0,76	disease	0,83	disease	0,65	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	2,86	0,63	0,9	NA	NA	N	0,45	N	0,83	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7003	7003	T	G	MI.4226	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1100	367	L	R	cTa/cGa	0,36	0,02	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-4,26	deleterious	-3,34	high_impact	5,09	damaging	0,48	damaging	0,03	deleterious	4,27	24	0,09	0,55	disease	0,69	disease	0,89	disease	0,77	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,6	0,45	0,9	NA	NA	P	0,66	P	0,9	disease_causing	0,89	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7003	7003	T	A	MI.4227	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1100	367	L	Q	cTa/cAa	0,36	0,02	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-3,95	deleterious	-3,31	high_impact	5,09	damaging	0,51	damaging	0,03	deleterious	4,34	24,1	0,11	0,55	disease	0,71	disease	0,84	disease	0,64	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,6	0,64	0,9	NA	NA	P	0,62	P	0,82	disease_causing	0,87	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7005	7005	C	A	MI.4228	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1102	368	H	N	Cac/Aac	-10,05	0	0	probably_damaging	1	deleterious	0	neutral	2,14	deleterious	-4,36	deleterious	-3,84	high_impact	4,61	damaging	0,55	damaging	0,04	deleterious	4,03	23,6	0,39	0,55	disease	0,69	disease	0,87	disease	0,81	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,16	0,57	0,9	3,51	7,83	N	0,5	N	0,86	polymorphism	0,97	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7005	7005	C	G	MI.4229	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1102	368	H	D	Cac/Gac	-10,05	0	0	probably_damaging	1	deleterious	0	neutral	2,13	deleterious	-4,63	deleterious	-4,94	high_impact	4,46	damaging	0,5	damaging	0,03	deleterious	3,99	23,6	0,23	0,55	disease	0,7	disease	0,89	disease	0,86	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,02	0,45	0,9	3,51	7,83	N	0,49	N	0,97	polymorphism	0,9	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8725	8725	A	C	MI.423	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	199	67	T	P	Acc/Ccc	-1,03	0	0,01	possibly_damaging	0,56	neutral	0,32	neutral	4,35	neutral	-0,73	deleterious	-2,92	neutral_impact	0,22	neutral	0,87	neutral	0,41	deleterious	3,11	22,5	0,28	0,65	neutral	0,46	disease	0,87	neutral	0,24	disease	0,52	0	neutral	0,68	neutral	0,38	neutral	-3	deleterious	0,69	medium_impact	-0,86	medium_impact	0,11	medium_impact	-0,91	0,64	0,9	13,27	10,97	N	0,3	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7005	7005	C	T	MI.4230	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1102	368	H	Y	Cac/Tac	-10,05	0	0	probably_damaging	1	deleterious	0	neutral	2,09	deleterious	-6,14	deleterious	-3,29	high_impact	5,16	damaging	0,56	damaging	0,03	deleterious	3,83	23,4	0,36	0,55	neutral	0,34	disease	0,9	disease	0,81	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,39	0,9	3,51	7,83	P	0,61	P	0,72	polymorphism	0,96	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7006	7006	A	G	MI.4231	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1103	368	H	R	cAc/cGc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,14	deleterious	-4,16	deleterious	-4,38	high_impact	4,82	damaging	0,58	damaging	0,04	deleterious	3,02	22,3	0,39	0,55	disease	0,67	disease	0,89	disease	0,83	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,35	0,45	0,9	3,51	7,83	P	0,73	P	0,85	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7006	7006	A	C	MI.4232	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1103	368	H	P	cAc/cCc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,1	deleterious	-5,48	deleterious	-5,49	high_impact	4,82	damaging	0,49	damaging	0,04	deleterious	3,31	22,9	0,25	0,55	disease	0,81	disease	0,89	disease	0,78	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,58	low_impact	-1,48	high_impact	3,35	0,34	0,9	3,51	7,83	P	0,65	P	0,9	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7006	7006	A	T	MI.4233	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1103	368	H	L	cAc/cTc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,11	deleterious	-5,21	deleterious	-6,03	high_impact	5,16	neutral	0,66	damaging	0,03	deleterious	3,85	23,4	0,23	0,55	disease	0,62	disease	0,93	disease	0,8	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,34	0,9	3,51	7,83	P	0,68	P	0,92	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7007	7007	C	A	MI.4234	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1104	368	H	Q	caC/caA	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,14	deleterious	-4,33	deleterious	-4,38	high_impact	4,46	neutral	0,62	damaging	0,04	deleterious	4,02	23,6	0,39	0,55	disease	0,67	disease	0,84	disease	0,77	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,02	0,55	0,9	3,51	7,83	P	0,55	P	0,83	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7007	7007	C	G	MI.4235	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1104	368	H	Q	caC/caG	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,14	deleterious	-4,33	deleterious	-4,38	high_impact	4,46	neutral	0,62	damaging	0,04	deleterious	3,7	23,3	0,39	0,55	disease	0,67	disease	0,84	disease	0,77	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,02	0,55	0,9	3,51	7,83	P	0,55	P	0,83	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7008	7008	G	A	MI.4236	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1105	369	D	N	Gac/Aac	-4,5	0	0	probably_damaging	1	deleterious	0	neutral	2,9	neutral	-0,11	deleterious	-2,75	high_impact	4,15	damaging	0,48	damaging	0,05	deleterious	4,38	24,1	0,53	0,6	neutral	0,39	disease	0,82	disease	0,65	disease	0,59	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,73	0,7	0,9	4,48	7,96	N	0,39	N	0,89	disease_causing	0,99	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7008	7008	G	C	MI.4237	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1105	369	D	H	Gac/Cac	-4,5	0	0	probably_damaging	1	deleterious	0	neutral	2,65	deleterious	-5,05	deleterious	-3,85	high_impact	5,19	damaging	0,58	damaging	0,04	deleterious	3,74	23,3	0,28	0,55	disease	0,86	disease	0,88	disease	0,79	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,63	0,9	4,48	7,96	P	0,65	P	0,97	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7008	7008	G	T	MI.4238	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1105	369	D	Y	Gac/Tac	-4,5	0	0	probably_damaging	1	deleterious	0	neutral	2,69	deleterious	-6,25	deleterious	-4,96	high_impact	4,84	damaging	0,55	damaging	0,05	deleterious	4,01	23,6	0,18	0,55	disease	0,92	disease	0,94	disease	0,78	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,92	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,46	0,9	4,48	7,96	P	0,56	P	0,94	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7009	7009	A	C	MI.4239	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1106	369	D	A	gAc/gCc	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-3,61	deleterious	-4,41	high_impact	4,84	neutral	0,63	damaging	0,09	deleterious	3,78	23,4	0,23	0,55	disease	0,74	disease	0,84	disease	0,75	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,57	0,9	4,48	7,96	P	0,73	P	0,85	disease_causing	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8725	8725	A	G	MI.424	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	199	67	T	A	Acc/Gcc	-1,03	0	0,01	benign	0,01	neutral	0,39	neutral	4,38	neutral	-0,23	neutral	-2,14	low_impact	0,9	neutral	0,96	neutral	0,78	neutral	1,38	12,66	0,61	0,7	disease	0,54	disease	0,56	neutral	0,42	neutral	0,49	0	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,2	medium_impact	1,14	medium_impact	0,18	medium_impact	-0,33	0,41	0,9	13,27	10,97	N	0,28	N	0,63	polymorphism	1	0,03	rs879216744	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7009	7009	A	T	MI.4240	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1106	369	D	V	gAc/gTc	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-5,46	deleterious	-4,96	high_impact	5,19	damaging	0,55	damaging	0,05	deleterious	4	23,6	0,17	0,55	disease	0,87	disease	0,93	disease	0,78	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,4	0,9	4,48	7,96	P	0,67	P	0,93	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7009	7009	A	G	MI.4241	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1106	369	D	G	gAc/gGc	5,22	1	0	probably_damaging	1	deleterious	0	neutral	2,84	deleterious	-3,15	deleterious	-3,86	high_impact	4,5	damaging	0,58	damaging	0,06	deleterious	4,17	23,8	0,22	0,55	disease	0,78	disease	0,89	disease	0,75	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,54	0,9	4,48	7,96	P	0,54	P	0,85	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7010	7010	C	G	MI.4242	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1107	369	D	E	gaC/gaG	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-2,41	neutral	-2,2	high_impact	3,87	damaging	0,49	damaging	0,07	deleterious	3,96	23,6	0,44	0,55	disease	0,57	disease	0,82	disease	0,64	disease	0,6	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,47	0,6	0,9	4,48	7,96	P	0,5	N	0,65	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7010	7010	C	A	MI.4243	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1107	369	D	E	gaC/gaA	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-2,41	neutral	-2,2	high_impact	3,87	damaging	0,49	damaging	0,07	deleterious	4,29	24	0,44	0,55	disease	0,57	disease	0,82	disease	0,64	disease	0,6	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,47	0,6	0,9	4,48	7,96	P	0,5	N	0,65	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7011	7011	A	G	MI.4244	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1108	370	T	A	Acg/Gcg	-1,49	0	0	probably_damaging	0,99	deleterious	0	neutral	1,43	deleterious	-6,92	deleterious	-2,75	high_impact	5,16	neutral	0,72	damaging	0,1	deleterious	3,53	23,1	0,43	0,55	disease	0,55	disease	0,63	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	high_impact	3,67	0,59	0,9	2,14	6,69	P	0,66	P	0,69	disease_causing	0,95	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7011	7011	A	T	MI.4245	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1108	370	T	S	Acg/Tcg	-1,49	0	0	probably_damaging	0,99	deleterious	0,01	neutral	1,67	deleterious	-3,33	neutral	-2,19	medium_impact	3,1	neutral	0,66	damaging	0,09	deleterious	3,3	22,9	0,4	0,55	neutral	0,33	disease	0,68	disease	0,62	neutral	0,37	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-2,64	medium_impact	-0,92	medium_impact	1,76	0,75	0,9	2,14	6,69	N	0,27	N	0,79	disease_causing	0,88	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7011	7011	A	C	MI.4246	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1108	370	T	P	Acg/Ccg	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	1,42	deleterious	-8,28	deleterious	-3,3	high_impact	5,16	damaging	0,55	damaging	0,08	deleterious	3,56	23,1	0,16	0,55	disease	0,8	disease	0,76	disease	0,76	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,6	0,9	2,14	6,69	P	0,64	P	0,92	disease_causing	0,99	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7012	7012	C	T	MI.4247	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1109	370	T	M	aCg/aTg	8,69	1	0	probably_damaging	1	deleterious	0	neutral	1,41	deleterious	-9,37	deleterious	-3,3	high_impact	5,16	neutral	0,69	damaging	0,07	deleterious	4,21	23,9	0,36	0,55	disease	0,84	disease	0,77	disease	0,78	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,74	0,9	2,14	6,69	P	0,67	P	0,96	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7012	7012	C	A	MI.4248	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1109	370	T	K	aCg/aAg	8,69	1	0	probably_damaging	1	deleterious	0	neutral	1,42	deleterious	-8,11	deleterious	-3,3	high_impact	5,16	neutral	0,62	damaging	0,06	deleterious	4,65	24,5	0,22	0,55	disease	0,55	disease	0,82	disease	0,83	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,71	0,9	2,14	6,69	P	0,7	P	0,88	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7014	7014	T	A	MI.4249	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1111	371	Y	N	Tac/Aac	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	2,48	deleterious	-4,57	deleterious	-4,95	high_impact	5,19	damaging	0,51	damaging	0,09	deleterious	4,2	23,9	0,24	0,55	disease	0,79	disease	0,88	disease	0,8	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,21	0,9	4,29	7,68	P	0,64	P	0,94	polymorphism	0,67	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8725	8725	A	T	MI.425	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	199	67	T	S	Acc/Tcc	-1,03	0	0,01	benign	0,19	neutral	0,45	neutral	4,39	neutral	-0,23	neutral	-1,04	neutral_impact	0,6	neutral	0,91	neutral	0,86	deleterious	0,18	4,5	0,64	0,7	neutral	0,38	neutral	0,49	neutral	0,25	neutral	0,46	1	neutral	0,46	deleterious	0,63	neutral	-6	neutral	0,33	medium_impact	-0,16	medium_impact	0,24	medium_impact	-0,58	0,78	0,9	13,27	10,97	N	0,37	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7014	7014	T	C	MI.4250	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1111	371	Y	H	Tac/Cac	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-4,44	deleterious	-2,75	high_impact	4,64	damaging	0,52	damaging	0,09	deleterious	3,72	23,3	0,33	0,55	disease	0,8	disease	0,85	disease	0,85	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,19	0,44	0,9	4,29	7,68	P	0,55	P	0,61	polymorphism	0,96	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7014	7014	T	G	MI.4251	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1111	371	Y	D	Tac/Gac	-6,12	0	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-4,89	deleterious	-5,5	high_impact	5,19	damaging	0,54	damaging	0,07	deleterious	4,14	23,8	0,14	0,55	disease	0,84	disease	0,91	disease	0,85	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,28	0,9	4,29	7,68	P	0,62	P	0,98	polymorphism	0,73	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7015	7015	A	C	MI.4252	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1112	371	Y	S	tAc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-3,32	deleterious	-4,94	high_impact	5,19	neutral	0,62	damaging	0,11	deleterious	3,87	23,5	0,22	0,55	disease	0,68	disease	0,89	disease	0,78	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,26	0,9	4,29	7,68	P	0,76	P	0,9	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7015	7015	A	G	MI.4253	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1112	371	Y	C	tAc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,45	deleterious	-4,91	deleterious	-4,95	high_impact	5,19	damaging	0,53	damaging	0,06	deleterious	3,67	23,3	0,3	0,55	disease	0,86	disease	0,89	disease	0,81	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,24	0,9	4,29	7,68	P	0,69	P	0,89	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7015	7015	A	T	MI.4254	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1112	371	Y	F	tAc/tTc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-3,1	neutral	-2,2	high_impact	4,04	damaging	0,47	damaging	0,08	deleterious	3,59	23,2	0,26	0,55	neutral	0,47	disease	0,88	disease	0,73	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,63	0,52	0,9	4,29	7,68	P	0,6	P	0,5	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7017	7017	T	C	MI.4255	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1114	372	Y	H	Tac/Cac	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,73	deleterious	-4,56	deleterious	-2,75	high_impact	5,08	neutral	0,61	damaging	0,05	deleterious	3,76	23,3	0,3	0,55	disease	0,79	disease	0,87	disease	0,75	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,59	0,42	0,9	3,9	7,79	P	0,69	P	0,61	disease_causing	0,98	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7017	7017	T	A	MI.4256	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1114	372	Y	N	Tac/Aac	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,74	deleterious	-5,56	deleterious	-4,94	high_impact	4,39	damaging	0,56	damaging	0,05	deleterious	4,33	24	0,25	0,55	disease	0,9	disease	0,89	disease	0,7	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,95	0,24	0,9	3,9	7,79	N	0,33	N	0,94	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7017	7017	T	G	MI.4257	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1114	372	Y	D	Tac/Gac	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,73	deleterious	-6,63	deleterious	-5,5	high_impact	5,08	damaging	0,48	damaging	0,04	deleterious	4,08	23,7	0,15	0,55	disease	0,95	disease	0,92	disease	0,77	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,59	0,27	0,9	3,9	7,79	P	0,53	P	0,98	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7018	7018	A	G	MI.4258	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1115	372	Y	C	tAc/tGc	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,72	deleterious	-6,46	deleterious	-4,95	high_impact	5,08	damaging	0,56	damaging	0,04	deleterious	3,68	23,3	0,29	0,55	disease	0,95	disease	0,9	disease	0,7	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,59	0,22	0,9	3,9	7,79	P	0,64	P	0,89	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7018	7018	A	T	MI.4259	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1115	372	Y	F	tAc/tTc	5,91	1	0	probably_damaging	1	neutral	0,13	neutral	2,94	neutral	0,67	neutral	-2,2	medium_impact	2,67	damaging	0,6	damaging	0,04	deleterious	3,55	23,1	0,26	0,55	neutral	0,16	disease	0,86	neutral	0,42	neutral	0,37	3	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,75	low_impact	-3,58	medium_impact	-0,27	medium_impact	1,37	0,48	0,9	3,9	7,79	N	0,45	N	0,5	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8726	8726	C	G	MI.426	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	200	67	T	S	aCc/aGc	3,14	0,77	0	benign	0,19	neutral	0,45	neutral	4,39	neutral	-0,23	neutral	-1,04	neutral_impact	0,6	neutral	0,91	neutral	0,86	deleterious	0,31	5,77	0,64	0,7	neutral	0,38	neutral	0,49	neutral	0,25	neutral	0,46	1	neutral	0,46	deleterious	0,63	neutral	-6	neutral	0,33	medium_impact	-0,16	medium_impact	0,24	medium_impact	-0,58	0,78	0,9	13,27	10,97	N	0,32	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7018	7018	A	C	MI.4260	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1115	372	Y	S	tAc/tCc	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,75	deleterious	-4,97	deleterious	-4,95	high_impact	5,08	neutral	0,61	damaging	0,06	deleterious	3,83	23,4	0,23	0,55	disease	0,89	disease	0,9	disease	0,66	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,59	0,28	0,9	3,9	7,79	P	0,69	P	0,9	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7020	7020	G	A	MI.4261	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1117	373	V	I	Gtt/Att	-3,11	0	0	probably_damaging	0,98	deleterious	0,02	neutral	2,4	neutral	-2,52	neutral	-0,54	high_impact	3,91	neutral	0,67	damaging	0,17	deleterious	3,78	23,4	0,37	0,55	neutral	0,38	disease	0,62	disease	0,55	disease	0,54	1	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-2,35	medium_impact	-0,75	high_impact	2,51	0,84	0,9	1,75	6,65	N	0,41	N	0,24	polymorphism	0,82	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7020	7020	G	T	MI.4262	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1117	373	V	F	Gtt/Ttt	-3,11	0	0	probably_damaging	1	deleterious	0	neutral	2,19	deleterious	-6,83	deleterious	-2,71	high_impact	5,19	damaging	0,57	damaging	0,11	deleterious	3,99	23,6	0,13	0,55	disease	0,76	disease	0,92	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,69	0,54	0,9	1,75	6,65	P	0,64	P	0,86	disease_causing	0,89	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7020	7020	G	C	MI.4263	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1117	373	V	L	Gtt/Ctt	-3,11	0	0	probably_damaging	0,98	deleterious	0	neutral	2,3	deleterious	-3,76	neutral	-1,63	high_impact	4,38	neutral	0,62	damaging	0,14	deleterious	3,68	23,3	0,24	0,55	neutral	0,4	disease	0,8	disease	0,56	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,35	low_impact	-1,48	high_impact	2,95	0,68	0,9	1,75	6,65	N	0,38	N	0,55	polymorphism	0,58	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7021	7021	T	C	MI.4264	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1118	373	V	A	gTt/gCt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,24	deleterious	-5,86	neutral	-2,17	high_impact	4,64	damaging	0,53	damaging	0,17	deleterious	3,67	23,3	0,23	0,55	disease	0,68	disease	0,68	disease	0,69	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,19	0,44	0,9	1,75	6,65	P	0,6	P	0,47	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7021	7021	T	G	MI.4265	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1118	373	V	G	gTt/gGt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,19	deleterious	-8,26	deleterious	-3,8	high_impact	4,84	neutral	0,61	damaging	0,16	deleterious	3,94	23,5	0,1	0,55	disease	0,87	disease	0,85	disease	0,68	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,47	0,9	1,75	6,65	P	0,67	P	0,71	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7021	7021	T	A	MI.4266	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1118	373	V	D	gTt/gAt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,18	deleterious	-9	deleterious	-3,8	high_impact	4,84	neutral	0,63	damaging	0,13	deleterious	4,54	24,3	0,09	0,55	disease	0,91	disease	0,9	disease	0,78	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,37	0,5	0,9	1,75	6,65	P	0,69	P	0,83	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7023	7023	G	A	MI.4267	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1120	374	V	M	Gta/Ata	-5,89	0	0	probably_damaging	1	deleterious	0	neutral	2,25	deleterious	-5,28	neutral	-1,61	high_impact	4,76	neutral	0,69	damaging	0,07	deleterious	3,8	23,4	0,31	0,55	disease	0,68	disease	0,78	disease	0,73	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,93	0,95	5,65	8,39	P	0,61	P	0,82	polymorphism	0,91	0,25	.	.	.	.	.	.	COSM1138396	.	.	G7023A	MELAS-like syndrome	-	+	Reported	1
chrM	7023	7023	G	C	MI.4268	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1120	374	V	L	Gta/Cta	-5,89	0	0	probably_damaging	0,99	deleterious	0	neutral	2,31	deleterious	-3,62	neutral	-1,61	high_impact	4,42	neutral	0,67	damaging	0,05	deleterious	3,59	23,2	0,3	0,55	neutral	0,47	disease	0,82	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,64	low_impact	-1,48	high_impact	2,98	0,69	0,9	5,65	8,39	N	0,4	N	0,55	polymorphism	0,92	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7023	7023	G	T	MI.4269	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1120	374	V	L	Gta/Tta	-5,89	0	0	probably_damaging	0,99	deleterious	0	neutral	2,31	deleterious	-3,62	neutral	-1,61	high_impact	4,42	neutral	0,67	damaging	0,05	deleterious	3,75	23,3	0,3	0,55	neutral	0,47	disease	0,82	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,64	low_impact	-1,48	high_impact	2,98	0,69	0,9	5,65	8,39	N	0,4	N	0,55	polymorphism	0,92	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8726	8726	C	T	MI.427	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	200	67	T	I	aCc/aTc	3,14	0,77	0	possibly_damaging	0,48	neutral	0,3	neutral	4,34	neutral	-1,22	deleterious	-3,67	neutral_impact	0,24	neutral	0,87	neutral	0,53	deleterious	2,17	17,3	0,41	0,65	disease	0,66	disease	0,8	neutral	0,5	disease	0,69	4	neutral	0,67	neutral	0,41	neutral	-3	deleterious	0,58	medium_impact	-0,72	medium_impact	0,08	medium_impact	-0,89	0,5	0,9	13,27	10,97	N	0,3	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7024	7024	T	A	MI.4270	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1121	374	V	E	gTa/gAa	9,38	1	0	probably_damaging	1	deleterious	0	neutral	2,24	deleterious	-6,43	deleterious	-3,23	high_impact	5,11	neutral	0,65	damaging	0,08	deleterious	4,69	24,6	0,12	0,55	disease	0,81	disease	0,9	disease	0,81	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,56	0,9	5,65	8,39	P	0,73	P	0,84	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7024	7024	T	G	MI.4271	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1121	374	V	G	gTa/gGa	9,38	1	0	probably_damaging	1	deleterious	0	neutral	2,24	deleterious	-6,45	deleterious	-3,77	high_impact	5,11	neutral	0,65	damaging	0,1	deleterious	3,92	23,5	0,15	0,55	disease	0,8	disease	0,87	disease	0,73	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,55	0,9	5,65	8,39	P	0,72	P	0,71	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7024	7024	T	C	MI.4272	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1121	374	V	A	gTa/gCa	9,38	1	0	probably_damaging	1	deleterious	0	neutral	2,39	neutral	-2,58	neutral	-2,15	high_impact	4,56	neutral	0,67	damaging	0,1	deleterious	3,65	23,2	0,28	0,55	disease	0,59	disease	0,7	disease	0,69	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,11	0,58	0,9	5,65	8,39	P	0,54	P	0,47	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7026	7026	G	A	MI.4273	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1123	375	A	T	Gcc/Acc	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	2,04	deleterious	-5,83	neutral	-2,15	high_impact	4,76	damaging	0,45	damaging	0,13	deleterious	4,33	24	0,19	0,55	disease	0,7	disease	0,86	disease	0,59	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,52	0,9	3,12	7,31	P	0,62	P	0,2	disease_causing	1	0,26	.	.	.	.	.	.	COSM1133249	.	.	.	.	.	.	.	.
chrM	7026	7026	G	C	MI.4274	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1123	375	A	P	Gcc/Ccc	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	2,02	deleterious	-7,06	deleterious	-2,68	high_impact	5,11	damaging	0,46	damaging	0,11	deleterious	3,89	23,5	0,09	0,55	disease	0,85	disease	0,85	disease	0,77	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,75	0,9	3,12	7,31	P	0,64	P	0,85	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7026	7026	G	T	MI.4275	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1123	375	A	S	Gcc/Tcc	-3,34	0	0	probably_damaging	1	neutral	0,09	neutral	2,1	deleterious	-3,88	neutral	-1,6	high_impact	3,73	neutral	0,6	damaging	0,11	deleterious	3,79	23,4	0,16	0,55	neutral	0,5	disease	0,83	disease	0,57	disease	0,6	2	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,84	low_impact	-3,58	medium_impact	-0,37	high_impact	2,35	0,79	0,9	3,12	7,31	N	0,31	N	0,64	disease_causing	0,99	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7027	7027	C	T	MI.4276	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1124	375	A	V	gCc/gTc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,04	deleterious	-5,44	neutral	-2,15	high_impact	5,11	damaging	0,45	damaging	0,08	deleterious	4,52	24,3	0,22	0,55	disease	0,82	disease	0,89	disease	0,66	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,62	0,9	3,12	7,31	P	0,71	P	0,75	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7027	7027	C	G	MI.4277	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1124	375	A	G	gCc/gGc	7,53	1	0	probably_damaging	0,99	neutral	0,08	neutral	2,55	neutral	-1,11	neutral	-2,09	medium_impact	2,58	damaging	0,5	damaging	0,12	deleterious	4,04	23,7	0,13	0,55	neutral	0,24	disease	0,77	neutral	0,45	neutral	0,4	2	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,76	low_impact	-2,64	medium_impact	-0,4	medium_impact	1,28	0,8	0,9	3,12	7,31	P	0,5	N	0,56	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7027	7027	C	A	MI.4278	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1124	375	A	D	gCc/gAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,02	deleterious	-7,76	deleterious	-3,21	high_impact	5,11	damaging	0,51	damaging	0,09	deleterious	4,71	24,6	0,07	0,55	disease	0,89	disease	0,93	disease	0,75	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,62	0,66	0,9	3,12	7,31	P	0,64	P	0,89	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7029	7029	C	G	MI.4279	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1126	376	H	D	Cac/Gac	-9,13	0	0	probably_damaging	1	deleterious	0	deleterious	-1,53	deleterious	-13,51	deleterious	-4,8	high_impact	5,17	damaging	0,49	damaging	0,03	deleterious	3,96	23,6	0,18	0,55	disease	0,78	disease	0,91	disease	0,84	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,33	0,9	7,6	8,33	N	0,44	N	0,97	disease_causing	0,8	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8726	8726	C	A	MI.428	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	200	67	T	N	aCc/aAc	3,14	0,77	0	possibly_damaging	0,64	neutral	0,26	neutral	4,39	neutral	-0,43	neutral	-1,83	neutral_impact	0,28	neutral	0,83	neutral	0,57	deleterious	3,27	22,8	0,71	0,75	neutral	0,47	disease	0,71	neutral	0,28	disease	0,52	0	neutral	0,77	neutral	0,31	neutral	-3	deleterious	0,6	medium_impact	-0,99	medium_impact	0,04	medium_impact	-0,86	0,74	0,9	13,27	10,97	N	0,32	N	0,9	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7029	7029	C	A	MI.4280	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1126	376	H	N	Cac/Aac	-9,13	0	0	probably_damaging	1	deleterious	0	deleterious	-1,52	deleterious	-11,53	deleterious	-3,73	high_impact	5,17	damaging	0,55	damaging	0,04	deleterious	4,03	23,6	0,27	0,55	disease	0,81	disease	0,88	disease	0,78	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,36	0,9	7,6	8,33	P	0,53	P	0,86	disease_causing	0,54	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7029	7029	C	T	MI.4281	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1126	376	H	Y	Cac/Tac	-9,13	0	0	probably_damaging	1	deleterious	0	deleterious	-1,52	deleterious	-11,61	deleterious	-3,2	high_impact	4,82	damaging	0,57	damaging	0,03	deleterious	3,84	23,4	0,25	0,55	disease	0,87	disease	0,92	disease	0,79	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,35	0,4	0,9	7,6	8,33	N	0,53	P	0,72	disease_causing	0,59	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7030	7030	A	T	MI.4282	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1127	376	H	L	cAc/cTc	4,52	1	0	probably_damaging	1	deleterious	0	deleterious	-1,53	deleterious	-14,51	deleterious	-5,86	high_impact	5,17	neutral	0,65	damaging	0,03	deleterious	3,97	23,6	0,16	0,55	disease	0,86	disease	0,94	disease	0,79	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,37	0,9	7,6	8,33	P	0,51	P	0,92	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7030	7030	A	C	MI.4283	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1127	376	H	P	cAc/cCc	4,52	1	0	probably_damaging	1	deleterious	0	deleterious	-1,53	deleterious	-13,85	deleterious	-5,33	high_impact	5,17	damaging	0,51	damaging	0,04	deleterious	3,35	22,9	0,19	0,55	disease	0,89	disease	0,9	disease	0,86	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,39	0,9	7,6	8,33	P	0,5	N	0,9	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7030	7030	A	G	MI.4284	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1127	376	H	R	cAc/cGc	4,52	1	0	probably_damaging	1	deleterious	0	deleterious	-1,51	deleterious	-11,11	deleterious	-4,27	high_impact	5,17	damaging	0,59	damaging	0,03	deleterious	3,13	22,6	0,3	0,55	disease	0,81	disease	0,91	disease	0,82	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,34	0,9	7,6	8,33	P	0,59	P	0,85	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7031	7031	C	A	MI.4285	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1128	376	H	Q	caC/caA	7,07	1	0	probably_damaging	1	deleterious	0	deleterious	-1,52	deleterious	-12,23	deleterious	-4,26	high_impact	5,17	neutral	0,62	damaging	0,04	deleterious	3,92	23,5	0,28	0,55	disease	0,83	disease	0,87	disease	0,8	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,42	0,9	7,6	8,33	P	0,6	P	0,83	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7031	7031	C	G	MI.4286	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1128	376	H	Q	caC/caG	7,07	1	0	probably_damaging	1	deleterious	0	deleterious	-1,52	deleterious	-12,23	deleterious	-4,26	high_impact	5,17	neutral	0,62	damaging	0,04	deleterious	3,65	23,2	0,28	0,55	disease	0,83	disease	0,87	disease	0,8	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,68	0,42	0,9	7,6	8,33	P	0,6	P	0,83	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7032	7032	T	C	MI.4287	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1129	377	F	L	Ttc/Ctc	-2,65	0	0	probably_damaging	0,98	deleterious	0	neutral	2,57	deleterious	-3,85	deleterious	-3,2	high_impact	3,52	neutral	0,75	damaging	0,05	deleterious	4,26	23,9	0,29	0,55	neutral	0,35	disease	0,83	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-2,35	low_impact	-1,48	high_impact	2,15	0,56	0,9	1,56	6,85	N	0,3	N	0,83	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7032	7032	T	A	MI.4288	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1129	377	F	I	Ttc/Atc	-2,65	0	0	probably_damaging	0,99	deleterious	0	neutral	2,53	deleterious	-4,45	deleterious	-3,2	high_impact	4,8	neutral	0,76	damaging	0,07	deleterious	4,66	24,5	0,16	0,55	disease	0,66	disease	0,87	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	3,33	0,56	0,9	1,56	6,85	P	0,66	P	0,88	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7032	7032	T	G	MI.4289	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1129	377	F	V	Ttc/Gtc	-2,65	0	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-4,13	deleterious	-3,73	high_impact	5,14	neutral	0,74	damaging	0,07	deleterious	4,26	23,9	0,23	0,55	disease	0,67	disease	0,91	disease	0,74	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,65	0,61	0,9	1,56	6,85	P	0,7	P	0,84	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8728	8728	T	G	MI.429	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	202	68	W	G	Tga/Gga	-1,95	0	0	probably_damaging	0,99	neutral	0,21	neutral	4,28	neutral	-2,71	deleterious	-11,52	medium_impact	2,92	neutral	0,6	neutral	0,43	deleterious	3,81	23,4	0,29	0,65	disease	0,67	disease	0,85	disease	0,79	disease	0,66	3	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,81	low_impact	-2,65	medium_impact	-0,03	medium_impact	1,41	0,36	0,9	49,56	8,58	N	0,41	N	1	disease_causing	0,96	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7033	7033	T	A	MI.4290	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1130	377	F	Y	tTc/tAc	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,54	deleterious	-5,3	neutral	-1,6	high_impact	4,25	neutral	0,76	damaging	0,06	deleterious	4,35	24,1	0,21	0,55	disease	0,65	disease	0,84	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,35	low_impact	-1,48	high_impact	2,83	0,66	0,9	1,56	6,85	N	0,52	P	0,59	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7033	7033	T	G	MI.4291	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1130	377	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,47	deleterious	-7,09	deleterious	-4,27	high_impact	5,14	neutral	0,78	damaging	0,06	deleterious	4,21	23,9	0,22	0,55	disease	0,91	disease	0,87	disease	0,74	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,65	0,4	0,9	1,56	6,85	P	0,67	P	0,91	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7033	7033	T	C	MI.4292	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1130	377	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-5,02	deleterious	-4,27	high_impact	4,17	neutral	0,78	damaging	0,08	deleterious	4,36	24,1	0,2	0,55	disease	0,8	disease	0,88	disease	0,73	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,75	0,51	0,9	1,56	6,85	N	0,5	N	0,84	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7034	7034	C	G	MI.4293	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1131	377	F	L	ttC/ttG	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,57	deleterious	-3,85	deleterious	-3,2	high_impact	3,52	neutral	0,75	damaging	0,05	deleterious	4,47	24,2	0,29	0,55	neutral	0,35	disease	0,83	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-2,35	low_impact	-1,48	high_impact	2,15	0,56	0,9	1,56	6,85	N	0,47	N	0,83	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7034	7034	C	A	MI.4294	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1131	377	F	L	ttC/ttA	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,57	deleterious	-3,85	deleterious	-3,2	high_impact	3,52	neutral	0,75	damaging	0,05	deleterious	4,75	24,7	0,29	0,55	neutral	0,35	disease	0,83	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-2,35	low_impact	-1,48	high_impact	2,15	0,56	0,9	1,56	6,85	N	0,5	N	0,83	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7035	7035	C	A	MI.4295	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1132	378	H	N	Cac/Aac	-0,57	0,14	0	probably_damaging	1	deleterious	0	deleterious	-1,54	deleterious	-11,57	deleterious	-3,72	high_impact	5,16	damaging	0,54	damaging	0,04	deleterious	3,96	23,6	0,29	0,55	disease	0,84	disease	0,89	disease	0,79	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,47	0,9	3,9	8,09	P	0,54	P	0,86	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7035	7035	C	G	MI.4296	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1132	378	H	D	Cac/Gac	-0,57	0,14	0	probably_damaging	1	deleterious	0	deleterious	-1,55	deleterious	-13,55	deleterious	-4,79	high_impact	5,16	damaging	0,49	damaging	0,04	deleterious	3,95	23,6	0,19	0,55	disease	0,87	disease	0,91	disease	0,84	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,48	0,9	3,9	8,09	P	0,49	N	0,97	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7035	7035	C	T	MI.4297	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1132	378	H	Y	Cac/Tac	-0,57	0,14	0	probably_damaging	1	deleterious	0,01	deleterious	-1,53	deleterious	-10,63	deleterious	-3,19	high_impact	4,12	damaging	0,55	damaging	0,04	deleterious	3,78	23,4	0,29	0,55	disease	0,89	disease	0,92	disease	0,81	disease	0,86	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-3,58	medium_impact	-0,92	high_impact	2,71	0,54	0,9	3,9	8,09	N	0,39	N	0,72	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7036	7036	A	G	MI.4298	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1133	378	H	R	cAc/cGc	7,3	1	0	probably_damaging	1	deleterious	0	deleterious	-1,55	deleterious	-13,21	deleterious	-4,25	high_impact	4,62	damaging	0,56	damaging	0,04	deleterious	3,07	22,4	0,33	0,55	neutral	0,35	disease	0,92	disease	0,79	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,17	0,54	0,9	3,9	8,09	N	0,45	N	0,85	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7036	7036	A	T	MI.4299	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1133	378	H	L	cAc/cTc	7,3	1	0	probably_damaging	1	deleterious	0	deleterious	-1,55	deleterious	-14,92	deleterious	-5,85	high_impact	5,16	neutral	0,63	damaging	0,03	deleterious	3,92	23,5	0,17	0,55	disease	0,86	disease	0,94	disease	0,78	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,48	0,9	3,9	8,09	P	0,52	P	0,92	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8545	8545	G	C	MI.43	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	19	7	A	P	Gct/Cct	-1,03	0	0,01	benign	0,25	deleterious	0,02	neutral	4,61	neutral	-2,12	neutral	-1,51	low_impact	1,7	neutral	0,72	neutral	0,36	deleterious	2,08	16,7	0,23	0,65	disease	0,7	disease	0,79	disease	0,62	disease	0,77	5	neutral	0,98	neutral	0,39	neutral	-2	deleterious	0,6	medium_impact	-0,3	medium_impact	-0,66	medium_impact	0,36	0,77	0,9	9,29	10,06	N	0,28	N	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8728	8728	T	C	MI.430	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	202	68	W	R	Tga/Cga	-1,95	0	0	probably_damaging	1	neutral	0,15	neutral	4,31	deleterious	-3,17	deleterious	-12,41	high_impact	3,6	damaging	0,48	damaging	0,25	deleterious	3,43	23	0,38	0,65	disease	0,74	disease	0,91	disease	0,83	disease	0,86	7	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,13	medium_impact	1,99	0,36	0,9	49,56	8,58	N	0,47	N	0,97	disease_causing	0,9	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7036	7036	A	C	MI.4300	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1133	378	H	P	cAc/cCc	7,3	1	0	probably_damaging	1	deleterious	0	deleterious	-1,55	deleterious	-13,3	deleterious	-5,32	high_impact	5,16	damaging	0,47	damaging	0,04	deleterious	3,29	22,8	0,2	0,55	disease	0,91	disease	0,9	disease	0,87	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,67	0,43	0,9	3,9	8,09	P	0,57	P	0,9	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7037	7037	C	A	MI.4301	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1134	378	H	Q	caC/caA	8,69	1	0	probably_damaging	1	deleterious	0	deleterious	-1,54	deleterious	-12,1	deleterious	-4,25	high_impact	4,62	damaging	0,59	damaging	0,04	deleterious	3,89	23,5	0,33	0,55	disease	0,77	disease	0,86	disease	0,78	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,17	0,54	0,9	3,9	8,09	P	0,49	N	0,83	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7037	7037	C	G	MI.4302	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1134	378	H	Q	caC/caG	8,69	1	0	probably_damaging	1	deleterious	0	deleterious	-1,54	deleterious	-12,1	deleterious	-4,25	high_impact	4,62	damaging	0,59	damaging	0,04	deleterious	3,64	23,2	0,33	0,55	disease	0,77	disease	0,86	disease	0,78	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,17	0,54	0,9	3,9	8,09	P	0,49	N	0,83	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7038	7038	T	C	MI.4303	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1135	379	Y	H	Tat/Cat	-0,1	0,79	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-4,09	deleterious	-2,66	high_impact	4,79	neutral	0,66	damaging	0,11	deleterious	3,76	23,3	0,33	0,55	disease	0,78	disease	0,86	disease	0,72	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,32	0,43	0,9	2,34	7,1	P	0,68	P	0,61	disease_causing	0,99	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7038	7038	T	A	MI.4304	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1135	379	Y	N	Tat/Aat	-0,1	0,79	0	probably_damaging	1	deleterious	0	neutral	2,58	neutral	-2,43	deleterious	-4,8	high_impact	4,79	damaging	0,59	damaging	0,12	deleterious	4,31	24	0,29	0,55	disease	0,61	disease	0,9	disease	0,72	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,32	0,27	0,9	2,34	7,1	P	0,65	P	0,94	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7038	7038	T	G	MI.4305	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1135	379	Y	D	Tat/Gat	-0,1	0,79	0	probably_damaging	1	deleterious	0	neutral	2,55	deleterious	-4,69	deleterious	-5,33	high_impact	5,13	neutral	0,63	damaging	0,1	deleterious	4,04	23,7	0,17	0,55	disease	0,83	disease	0,92	disease	0,8	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,64	0,33	0,9	2,34	7,1	P	0,65	P	0,98	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7039	7039	A	C	MI.4306	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1136	379	Y	S	tAt/tCt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,59	neutral	-2,44	deleterious	-4,79	high_impact	4,79	neutral	0,7	damaging	0,15	deleterious	3,94	23,5	0,25	0,55	disease	0,63	disease	0,91	disease	0,68	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,32	0,31	0,9	2,34	7,1	P	0,7	P	0,9	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7039	7039	A	G	MI.4307	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1136	379	Y	C	tAt/tGt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-3,86	deleterious	-4,8	high_impact	5,13	neutral	0,62	damaging	0,09	deleterious	3,7	23,3	0,31	0,55	disease	0,81	disease	0,91	disease	0,73	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,64	0,26	0,9	2,34	7,1	P	0,72	P	0,89	disease_causing	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7039	7039	A	T	MI.4308	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1136	379	Y	F	tAt/tTt	7,53	1	0	probably_damaging	0,99	deleterious	0,03	neutral	2,61	neutral	-1,45	neutral	-2,13	medium_impact	3,48	damaging	0,51	damaging	0,13	deleterious	3,64	23,2	0,31	0,55	disease	0,5	disease	0,91	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,84	low_impact	-2,64	medium_impact	-0,65	high_impact	2,11	0,58	0,9	2,34	7,1	P	0,5	N	0,5	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7041	7041	G	A	MI.4309	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1138	380	V	I	Gtc/Atc	-0,8	0,07	0	probably_damaging	0,98	deleterious	0	neutral	2,54	neutral	-1,73	neutral	-0,53	high_impact	4,14	damaging	0,52	neutral	0,6	deleterious	3,78	23,4	0,46	0,55	disease	0,53	disease	0,75	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,35	low_impact	-1,48	high_impact	2,72	0,91	0,95	1,75	6,67	P	0,57	P	0,24	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	G7041A	Prostate Cancer	+	-	Reported	1
chrM	8729	8729	G	C	MI.431	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	203	68	W	S	tGa/tCa	5,91	1	0	probably_damaging	1	neutral	0,55	neutral	4,36	neutral	-2,22	deleterious	-12,36	medium_impact	2,08	damaging	0,58	neutral	0,46	deleterious	3,99	23,6	0,3	0,65	disease	0,54	disease	0,88	disease	0,76	disease	0,65	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,83	low_impact	-3,6	medium_impact	0,34	medium_impact	0,69	0,37	0,9	49,56	8,58	N	0,43	N	0,98	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7041	7041	G	C	MI.4310	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1138	380	V	L	Gtc/Ctc	-0,8	0,07	0	probably_damaging	0,98	deleterious	0	neutral	2,54	neutral	-2,23	neutral	-1,6	high_impact	4,57	damaging	0,57	neutral	0,52	deleterious	3,65	23,2	0,32	0,55	disease	0,55	disease	0,84	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,35	low_impact	-1,48	high_impact	3,12	0,71	0,9	1,75	6,67	N	0,52	P	0,55	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7041	7041	G	T	MI.4311	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1138	380	V	F	Gtc/Ttc	-0,8	0,07	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-3,57	deleterious	-2,66	high_impact	4,78	damaging	0,53	neutral	0,47	deleterious	3,91	23,5	0,14	0,55	disease	0,76	disease	0,95	disease	0,7	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,32	0,74	0,9	1,75	6,67	P	0,68	P	0,86	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7042	7042	T	A	MI.4312	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1139	380	V	D	gTc/gAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,44	deleterious	-5,55	deleterious	-3,73	high_impact	5,12	damaging	0,57	neutral	0,5	deleterious	4,52	24,3	0,09	0,55	disease	0,87	disease	0,92	disease	0,77	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,63	0,65	0,9	1,75	6,67	P	0,7	P	0,83	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7042	7042	T	C	MI.4313	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1139	380	V	A	gTc/gCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-2,48	neutral	-2,13	high_impact	3,88	damaging	0,56	neutral	0,57	deleterious	3,62	23,2	0,39	0,55	disease	0,59	disease	0,72	disease	0,63	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,48	0,7	0,9	1,75	6,67	P	0,54	P	0,47	disease_causing	1	0,12	.	.	.	.	.	.	COSM1138398	.	.	.	.	.	.	.	.
chrM	7042	7042	T	G	MI.4314	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1139	380	V	G	gTc/gGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-4,63	deleterious	-3,73	high_impact	5,12	damaging	0,58	neutral	0,59	deleterious	3,89	23,5	0,15	0,55	neutral	0,39	disease	0,88	disease	0,7	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,63	0,57	0,9	1,75	6,67	P	0,62	P	0,71	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7044	7044	C	A	MI.4315	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1141	381	L	M	Cta/Ata	-14,22	0	0	probably_damaging	1	deleterious	0	neutral	2,52	neutral	-1,42	neutral	-1,07	high_impact	3,62	damaging	0,56	damaging	0,09	deleterious	3,8	23,4	0,29	0,55	neutral	0,45	disease	0,74	disease	0,55	disease	0,58	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,24	0,71	0,9	3,12	6,67	N	0,27	N	0,59	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7044	7044	C	G	MI.4316	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1141	381	L	V	Cta/Gta	-14,22	0	0	probably_damaging	0,97	deleterious	0	neutral	2,6	neutral	-0,89	neutral	-1,6	medium_impact	3,38	damaging	0,53	damaging	0,06	deleterious	3,45	23	0,36	0,55	neutral	0,39	disease	0,85	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,78	low_impact	-2,18	low_impact	-1,48	high_impact	2,02	0,59	0,9	3,12	6,67	N	0,27	N	0,66	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7045	7045	T	A	MI.4317	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1142	381	L	Q	cTa/cAa	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	2,32	deleterious	-5,69	deleterious	-3,2	high_impact	5,09	damaging	0,56	damaging	0,05	deleterious	4,17	23,8	0,18	0,55	disease	0,86	disease	0,89	disease	0,64	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,6	0,62	0,9	3,12	6,67	P	0,61	P	0,82	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7045	7045	T	C	MI.4318	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1142	381	L	P	cTa/cCa	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	2,32	deleterious	-6,07	deleterious	-3,74	high_impact	5,09	damaging	0,41	damaging	0,05	deleterious	4,01	23,6	0,17	0,55	neutral	0,4	disease	0,88	disease	0,72	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,6	0,43	0,9	3,12	6,67	P	0,49	N	0,83	disease_causing	0,75	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7045	7045	T	G	MI.4319	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1142	381	L	R	cTa/cGa	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	2,32	deleterious	-5,58	deleterious	-3,2	high_impact	5,09	damaging	0,53	damaging	0,04	deleterious	4,28	24	0,17	0,55	disease	0,86	disease	0,95	disease	0,75	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,93	low_impact	-3,58	low_impact	-1,48	high_impact	3,6	0,51	0,9	3,12	6,67	P	0,59	P	0,9	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8729	8729	G	T	MI.432	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	203	68	W	L	tGa/tTa	5,91	1	0	probably_damaging	0,99	neutral	0,37	neutral	4,41	neutral	-0,24	deleterious	-11,52	medium_impact	2,37	damaging	0,57	neutral	0,33	deleterious	4,2	23,9	0,25	0,65	disease	0,53	disease	0,84	disease	0,77	disease	0,77	5	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,8	low_impact	-2,65	medium_impact	0,16	medium_impact	0,93	0,3	0,9	49,56	8,58	N	0,46	N	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7047	7047	T	G	MI.4320	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1144	382	S	A	Tca/Gca	-5,66	0	0	benign	0,07	deleterious	0	neutral	2,8	neutral	-0,06	neutral	-1,6	high_impact	4,36	damaging	0,58	damaging	0,13	deleterious	3,77	23,4	0,39	0,55	neutral	0,38	disease	0,75	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,47	deleterious	2	neutral	0,25	medium_impact	0,3	low_impact	-1,48	high_impact	2,93	0,7	0,9	7,8	8,18	N	0,4	N	0,35	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7047	7047	T	A	MI.4321	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1144	382	S	T	Tca/Aca	-5,66	0	0	benign	0,06	deleterious	0,02	neutral	2,72	neutral	-1,4	neutral	-1,6	high_impact	4,16	damaging	0,51	damaging	0,08	deleterious	3,8	23,4	0,31	0,55	neutral	0,43	disease	0,8	disease	0,59	disease	0,67	3	neutral	0,98	deleterious	0,48	deleterious	2	neutral	0,3	medium_impact	0,37	medium_impact	-0,75	high_impact	2,74	0,83	0,9	7,8	8,18	N	0,36	N	0,43	polymorphism	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7047	7047	T	C	MI.4322	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1144	382	S	P	Tca/Cca	-5,66	0	0	benign	0	deleterious	0	neutral	2,68	deleterious	-3,31	deleterious	-2,66	high_impact	4,5	damaging	0,36	damaging	0,08	deleterious	4,06	23,7	0,18	0,55	disease	0,67	disease	0,87	disease	0,77	disease	0,8	6	deleterious	1	deleterious	0,5	deleterious	2	neutral	0,34	high_impact	2,07	low_impact	-1,48	high_impact	3,06	0,7	0,9	7,8	8,18	P	0,51	P	0,91	polymorphism	0,96	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7048	7048	C	G	MI.4323	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1145	382	S	W	tCa/tGa	5,91	1	0	probably_damaging	0,96	deleterious	0	neutral	2,72	neutral	-1,48	deleterious	-3,74	high_impact	5,05	damaging	0,49	damaging	0,06	deleterious	4,37	24,1	0,17	0,55	disease	0,82	disease	0,93	disease	0,69	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-2,06	low_impact	-1,48	high_impact	3,56	0,51	0,9	7,8	8,18	P	0,66	P	0,94	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7048	7048	C	T	MI.4324	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1145	382	S	L	tCa/tTa	5,91	1	0	benign	0,41	deleterious	0	neutral	2,87	neutral	0,6	deleterious	-3,2	high_impact	4,36	damaging	0,55	damaging	0,05	deleterious	4,68	24,6	0,23	0,55	neutral	0,36	disease	0,91	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,57	medium_impact	-0,61	low_impact	-1,48	high_impact	2,93	0,85	0,9	7,8	8,18	N	0,43	N	0,9	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7050	7050	A	G	MI.4325	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1147	383	M	V	Ata/Gta	-8,2	0	0	probably_damaging	0,94	deleterious	0	neutral	2,82	neutral	0,16	neutral	-2,06	high_impact	3,95	damaging	0,56	neutral	0,39	deleterious	2,9	21,8	0,4	0,55	neutral	0,3	disease	0,93	disease	0,69	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,75	low_impact	-1,88	low_impact	-1,48	high_impact	2,55	0,49	0,9	5,26	8,17	N	0,4	N	0,88	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7050	7050	A	T	MI.4326	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1147	383	M	L	Ata/Tta	-8,2	0	0	probably_damaging	0,91	neutral	0,21	neutral	2,89	neutral	1,04	neutral	-1,5	medium_impact	2,91	damaging	0,59	neutral	0,45	deleterious	3,54	23,1	0,33	0,55	neutral	0,16	disease	0,83	neutral	0,48	neutral	0,49	0	neutral	0,94	neutral	0,15	deleterious	1	deleterious	0,62	low_impact	-1,7	medium_impact	-0,13	medium_impact	1,59	0,44	0,9	5,26	8,17	N	0,37	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7050	7050	A	C	MI.4327	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1147	383	M	L	Ata/Cta	-8,2	0	0	probably_damaging	0,91	neutral	0,21	neutral	2,89	neutral	1,04	neutral	-1,5	medium_impact	2,91	damaging	0,59	neutral	0,45	deleterious	3,4	23	0,33	0,55	neutral	0,16	disease	0,83	neutral	0,48	neutral	0,49	0	neutral	0,94	neutral	0,15	deleterious	1	deleterious	0,62	low_impact	-1,7	medium_impact	-0,13	medium_impact	1,59	0,44	0,9	5,26	8,17	N	0,37	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7051	7051	T	A	MI.4328	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1148	383	M	K	aTa/aAa	8,69	1	0	probably_damaging	0,97	deleterious	0	neutral	2,76	neutral	-1,19	deleterious	-3,13	high_impact	4,92	damaging	0,58	neutral	0,39	deleterious	4,34	24	0,23	0,55	disease	0,58	disease	0,95	disease	0,76	disease	0,88	8	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-2,18	low_impact	-1,48	high_impact	3,44	0,46	0,9	5,26	8,17	P	0,71	P	0,93	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7051	7051	T	C	MI.4329	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1148	383	M	T	aTa/aCa	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,82	neutral	0,19	deleterious	-3,11	high_impact	4,58	damaging	0,52	neutral	0,39	deleterious	3,1	22,5	0,43	0,55	neutral	0,42	disease	0,92	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,64	low_impact	-1,48	high_impact	3,13	0,39	0,9	5,26	8,17	P	0,52	P	0,79	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8730	8730	A	C	MI.433	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	204	68	W	C	tgA/tgC	7,3	1	0	probably_damaging	1	neutral	0,09	neutral	4,28	deleterious	-3,65	deleterious	-11,57	high_impact	3,6	damaging	0,45	damaging	0,24	deleterious	3,94	23,5	0,29	0,65	disease	0,62	disease	0,9	disease	0,8	disease	0,84	7	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,28	medium_impact	1,99	0,24	0,9	49,56	8,58	P	0,57	P	1	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7052	7052	A	C	MI.4330	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1149	383	M	I	atA/atC	7,53	1	0	probably_damaging	0,96	deleterious	0	neutral	2,81	neutral	0,05	neutral	-2,05	high_impact	3,64	damaging	0,54	neutral	0,49	deleterious	3,51	23,1	0,41	0,55	neutral	0,29	disease	0,93	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,78	low_impact	-2,06	low_impact	-1,48	high_impact	2,26	0,62	0,9	5,26	8,17	P	0,5	N	0,87	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7052	7052	A	T	MI.4331	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1149	383	M	I	atA/atT	7,53	1	0	probably_damaging	0,96	deleterious	0	neutral	2,81	neutral	0,05	neutral	-2,05	high_impact	3,64	damaging	0,54	neutral	0,49	deleterious	3,68	23,3	0,41	0,55	neutral	0,29	disease	0,93	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,78	low_impact	-2,06	low_impact	-1,48	high_impact	2,26	0,62	0,9	5,26	8,17	P	0,52	P	0,87	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7053	7053	G	C	MI.4332	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1150	384	G	R	Gga/Cga	0,36	0,99	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-3,84	deleterious	-4,26	high_impact	5,05	damaging	0,49	damaging	0,03	deleterious	3,99	23,6	0,16	0,55	disease	0,82	disease	0,94	disease	0,8	disease	0,89	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,85	0,9	2,14	6,66	P	0,63	P	0,95	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7053	7053	G	T	MI.4333	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1150	384	G	W	Gga/Tga	0,36	0,99	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-5,31	deleterious	-4,26	high_impact	5,05	damaging	0,46	damaging	0,04	deleterious	4,47	24,2	0,13	0,55	disease	0,96	disease	0,93	disease	0,74	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,4	0,9	2,14	6,66	P	0,61	P	0,83	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7054	7054	G	T	MI.4334	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1151	384	G	V	gGa/gTa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,62	neutral	-1,35	deleterious	-4,8	high_impact	5,05	damaging	0,52	damaging	0,04	deleterious	3,86	23,5	0,16	0,55	disease	0,72	disease	0,94	disease	0,71	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,53	0,9	2,14	6,66	P	0,69	P	0,93	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7054	7054	G	A	MI.4335	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1151	384	G	E	gGa/gAa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-3,91	deleterious	-4,26	high_impact	5,05	damaging	0,43	damaging	0,03	deleterious	3,98	23,6	0,22	0,55	disease	0,8	disease	0,91	disease	0,79	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,62	0,9	2,14	6,66	P	0,76	P	0,93	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7054	7054	G	C	MI.4336	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1151	384	G	A	gGa/gCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-0,26	deleterious	-3,2	high_impact	3,66	neutral	0,62	damaging	0,06	deleterious	3,22	22,7	0,21	0,55	neutral	0,25	disease	0,78	disease	0,59	disease	0,63	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	high_impact	2,28	0,7	0,9	2,14	6,66	N	0,42	N	0,64	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7056	7056	G	C	MI.4337	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1153	385	A	P	Gct/Cct	-4,73	0	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-3,8	deleterious	-2,6	high_impact	4,17	damaging	0,41	damaging	0,28	deleterious	3,97	23,6	0,14	0,55	disease	0,69	disease	0,9	disease	0,71	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,75	0,81	0,9	3,31	6,67	P	0,51	P	0,85	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7056	7056	G	T	MI.4338	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1153	385	A	S	Gct/Tct	-4,73	0	0	probably_damaging	1	neutral	0,06	neutral	2,72	neutral	-0,89	neutral	-1,55	medium_impact	3,38	damaging	0,56	neutral	0,32	deleterious	3,86	23,4	0,33	0,55	neutral	0,36	disease	0,87	neutral	0,49	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,82	low_impact	-3,58	medium_impact	-0,47	high_impact	2,02	0,76	0,9	3,31	6,67	N	0,34	N	0,64	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7056	7056	G	A	MI.4339	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1153	385	A	T	Gct/Act	-4,73	0	0	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-0,46	neutral	-2,06	high_impact	4,42	damaging	0,41	damaging	0,22	deleterious	4,32	24	0,44	0,55	neutral	0,22	disease	0,88	disease	0,57	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,98	0,66	0,9	3,31	6,67	P	0,58	P	0,2	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8730	8730	A	T	MI.434	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	204	68	W	C	tgA/tgT	7,3	1	0	probably_damaging	1	neutral	0,09	neutral	4,28	deleterious	-3,65	deleterious	-11,57	high_impact	3,6	damaging	0,45	damaging	0,24	deleterious	4,03	23,6	0,29	0,65	disease	0,62	disease	0,9	disease	0,8	disease	0,84	7	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,28	medium_impact	1,99	0,24	0,9	49,56	8,58	P	0,58	P	1	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7057	7057	C	T	MI.4340	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1154	385	A	V	gCt/gTt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,81	neutral	0	neutral	-2	medium_impact	2,79	damaging	0,42	damaging	0,18	deleterious	4,42	24,2	0,4	0,55	neutral	0,24	disease	0,92	neutral	0,5	disease	0,66	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	medium_impact	1,48	0,73	0,9	3,31	6,67	P	0,6	P	0,75	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7057	7057	C	A	MI.4341	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1154	385	A	D	gCt/gAt	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-4,29	deleterious	-3,1	high_impact	4,97	damaging	0,45	neutral	0,3	deleterious	4,6	24,4	0,17	0,55	disease	0,59	disease	0,94	disease	0,7	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,49	0,66	0,9	3,31	6,67	P	0,71	P	0,89	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7057	7057	C	G	MI.4342	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1154	385	A	G	gCt/gGt	6,14	1	0	probably_damaging	0,99	deleterious	0	neutral	2,65	neutral	-2,5	neutral	-2,04	high_impact	4,08	damaging	0,47	neutral	0,39	deleterious	4,03	23,7	0,3	0,55	disease	0,6	disease	0,85	disease	0,58	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,64	low_impact	-1,48	high_impact	2,67	0,78	0,9	3,31	6,67	P	0,57	P	0,56	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7059	7059	G	C	MI.4343	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1156	386	V	L	Gta/Cta	-7,74	0	0	probably_damaging	0,98	deleterious	0	neutral	2,68	neutral	-0,9	neutral	-1,56	medium_impact	3,48	neutral	0,69	damaging	0,05	deleterious	3,68	23,3	0,4	0,55	neutral	0,26	disease	0,81	neutral	0,4	disease	0,63	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-2,35	low_impact	-1,48	high_impact	2,11	0,75	0,9	2,34	6,59	N	0,3	N	0,55	polymorphism	0,95	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7059	7059	G	T	MI.4344	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1156	386	V	L	Gta/Tta	-7,74	0	0	probably_damaging	0,98	deleterious	0	neutral	2,68	neutral	-0,9	neutral	-1,56	medium_impact	3,48	neutral	0,69	damaging	0,05	deleterious	3,78	23,4	0,4	0,55	neutral	0,26	disease	0,81	neutral	0,4	disease	0,63	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-2,35	low_impact	-1,48	high_impact	2,11	0,75	0,9	2,34	6,59	N	0,3	N	0,55	polymorphism	0,95	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7059	7059	G	A	MI.4345	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1156	386	V	M	Gta/Ata	-7,74	0	0	probably_damaging	1	deleterious	0	neutral	2,54	deleterious	-3,18	neutral	-1,57	high_impact	4,08	neutral	0,7	damaging	0,07	deleterious	3,81	23,4	0,36	0,55	neutral	0,48	disease	0,81	disease	0,53	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	2,67	0,79	0,9	2,34	6,59	N	0,27	N	0,82	polymorphism	0,94	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7060	7060	T	A	MI.4346	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1157	386	V	E	gTa/gAa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,52	deleterious	-4,53	deleterious	-3,18	high_impact	4,63	neutral	0,67	damaging	0,08	deleterious	4,71	24,6	0,12	0,55	neutral	0,33	disease	0,91	disease	0,73	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,18	0,58	0,9	2,34	6,59	N	0,5	N	0,84	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7060	7060	T	C	MI.4347	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1157	386	V	A	gTa/gCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,68	neutral	-1,47	neutral	-2,12	high_impact	3,83	neutral	0,68	damaging	0,1	deleterious	3,61	23,2	0,33	0,55	neutral	0,43	disease	0,71	disease	0,59	disease	0,6	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,44	0,4	0,9	2,34	6,59	P	0,49	N	0,47	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7060	7060	T	G	MI.4348	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1157	386	V	G	gTa/gGa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-4,09	deleterious	-3,71	high_impact	4,08	neutral	0,66	damaging	0,1	deleterious	3,88	23,5	0,16	0,55	disease	0,74	disease	0,86	disease	0,61	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,67	0,54	0,9	2,34	6,59	N	0,44	N	0,71	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7062	7062	T	A	MI.4349	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1159	387	F	I	Ttt/Att	-10,75	0	0	probably_damaging	1	deleterious	0	neutral	2,62	neutral	-1,34	deleterious	-3,17	medium_impact	3,09	neutral	0,74	damaging	0,08	deleterious	4,44	24,2	0,2	0,55	neutral	0,34	disease	0,93	disease	0,64	disease	0,76	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	medium_impact	1,75	0,64	0,9	3,7	8,35	N	0,27	N	0,88	polymorphism	0,76	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8731	8731	T	G	MI.435	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	205	69	S	A	Tct/Gct	1,75	0,85	0	probably_damaging	0,97	neutral	1	neutral	4,45	neutral	0,64	neutral	0,03	neutral_impact	-1,31	neutral	0,87	neutral	0,96	deleterious	0,83	9,67	0,49	0,65	neutral	0,27	neutral	0,13	neutral	0,28	neutral	0,22	6	neutral	0,97	deleterious	0,52	neutral	-2	deleterious	0,66	low_impact	-2,19	high_impact	1,98	low_impact	-2,22	0,8	0,9	12,39	14,86	N	0,29	N	0,03	polymorphism	0,97	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7062	7062	T	G	MI.4350	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1159	387	F	V	Ttt/Gtt	-10,75	0	0	probably_damaging	1	deleterious	0	neutral	2,6	neutral	-1,56	deleterious	-3,7	high_impact	4,07	neutral	0,72	damaging	0,07	deleterious	4,05	23,7	0,2	0,55	neutral	0,39	disease	0,94	disease	0,65	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,66	0,58	0,9	3,7	8,35	N	0,32	N	0,84	polymorphism	0,6	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7062	7062	T	C	MI.4351	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1159	387	F	L	Ttt/Ctt	-10,75	0	0	probably_damaging	0,99	deleterious	0	neutral	2,72	neutral	-0,48	deleterious	-3,17	high_impact	4	neutral	0,76	damaging	0,08	deleterious	4,07	23,7	0,29	0,55	neutral	0,26	disease	0,88	disease	0,61	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	high_impact	2,59	0,68	0,9	3,7	8,35	N	0,29	N	0,83	polymorphism	0,74	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7063	7063	T	C	MI.4352	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1160	387	F	S	tTt/tCt	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,53	neutral	-2,74	deleterious	-4,23	high_impact	3,85	neutral	0,76	damaging	0,08	deleterious	4,37	24,1	0,14	0,55	disease	0,58	disease	0,9	disease	0,64	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,46	0,53	0,9	3,7	8,35	N	0,46	N	0,84	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7063	7063	T	A	MI.4353	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1160	387	F	Y	tTt/tAt	5,91	1	0	probably_damaging	0,99	deleterious	0,04	neutral	2,58	neutral	-1,81	neutral	-1,58	high_impact	3,65	neutral	0,73	damaging	0,06	deleterious	4,37	24,1	0,23	0,55	disease	0,66	disease	0,87	neutral	0,49	disease	0,53	1	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,83	low_impact	-2,64	medium_impact	-0,58	high_impact	2,27	0,7	0,9	3,7	8,35	P	0,53	P	0,59	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7063	7063	T	G	MI.4354	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1160	387	F	C	tTt/tGt	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-3,84	deleterious	-4,23	high_impact	5,04	neutral	0,74	damaging	0,06	deleterious	4,22	23,9	0,17	0,55	disease	0,76	disease	0,92	disease	0,67	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,4	0,9	3,7	8,35	P	0,68	P	0,91	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7064	7064	T	G	MI.4355	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1161	387	F	L	ttT/ttG	4,76	1	0	probably_damaging	0,99	deleterious	0	neutral	2,72	neutral	-0,48	deleterious	-3,17	high_impact	4	neutral	0,76	damaging	0,08	deleterious	4,39	24,1	0,29	0,55	neutral	0,26	disease	0,88	disease	0,61	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	high_impact	2,59	0,68	0,9	3,7	8,35	N	0,5	N	0,83	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7064	7064	T	A	MI.4356	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1161	387	F	L	ttT/ttA	4,76	1	0	probably_damaging	0,99	deleterious	0	neutral	2,72	neutral	-0,48	deleterious	-3,17	high_impact	4	neutral	0,76	damaging	0,08	deleterious	4,53	24,3	0,29	0,55	neutral	0,26	disease	0,88	disease	0,61	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,64	low_impact	-1,48	high_impact	2,59	0,68	0,9	3,7	8,35	P	0,51	P	0,83	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7065	7065	G	A	MI.4357	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1162	388	A	T	Gcc/Acc	-7,97	0	0	probably_damaging	1	neutral	0,06	neutral	2,59	neutral	-1,83	neutral	-1,92	medium_impact	2,46	damaging	0,56	damaging	0,08	deleterious	4,34	24,1	0,39	0,55	disease	0,57	disease	0,83	neutral	0,33	disease	0,53	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,83	low_impact	-3,58	medium_impact	-0,47	medium_impact	1,17	0,84	0,9	4,09	8,05	N	0,27	N	0,2	polymorphism	0,72	0,04	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	7065	7065	G	C	MI.4358	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1162	388	A	P	Gcc/Ccc	-7,97	0	0	probably_damaging	1	deleterious	0	neutral	2,54	neutral	-2,91	neutral	-2,44	high_impact	4	damaging	0,53	damaging	0,05	deleterious	3,93	23,5	0,09	0,55	disease	0,55	disease	0,93	disease	0,65	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	2,59	0,83	0,9	4,09	8,05	N	0,3	N	0,85	disease_causing	0,58	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7065	7065	G	T	MI.4359	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1162	388	A	S	Gcc/Tcc	-7,97	0	0	probably_damaging	1	neutral	0,09	neutral	2,57	neutral	-2,09	neutral	-1,36	medium_impact	1,98	damaging	0,54	damaging	0,07	deleterious	3,81	23,4	0,27	0,55	neutral	0,49	disease	0,78	neutral	0,29	disease	0,5	0	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,8	low_impact	-3,58	medium_impact	-0,37	medium_impact	0,73	0,81	0,9	4,09	8,05	N	0,27	N	0,64	polymorphism	0,85	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8731	8731	T	A	MI.436	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	205	69	S	T	Tct/Act	1,75	0,85	0	probably_damaging	0,98	neutral	0,62	neutral	4,34	neutral	0,65	neutral	-1,21	neutral_impact	-0,53	neutral	0,9	neutral	0,9	deleterious	2,44	19,09	0,36	0,65	disease	0,58	neutral	0,42	neutral	0,34	disease	0,61	2	neutral	0,98	neutral	0,32	neutral	-2	deleterious	0,75	low_impact	-2,36	medium_impact	0,41	low_impact	-1,55	0,84	0,9	12,39	14,86	N	0,3	N	0,02	polymorphism	0,91	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7066	7066	C	G	MI.4360	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1163	388	A	G	gCc/gGc	7,3	1	0	probably_damaging	0,99	neutral	0,3	neutral	2,67	neutral	-0,89	neutral	-1,57	low_impact	1,84	damaging	0,46	damaging	0,06	deleterious	3	22,2	0,22	0,55	neutral	0,19	disease	0,74	neutral	0,27	neutral	0,47	1	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,72	low_impact	-2,64	medium_impact	-0,01	medium_impact	0,6	0,85	0,9	4,09	8,05	P	0,51	P	0,56	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7066	7066	C	T	MI.4361	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1163	388	A	V	gCc/gTc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,64	neutral	-1,17	neutral	-2,03	high_impact	4	damaging	0,55	damaging	0,06	deleterious	4,59	24,4	0,28	0,55	neutral	0,41	disease	0,92	disease	0,53	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,59	0,81	0,9	4,09	8,05	P	0,5	N	0,75	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7066	7066	C	A	MI.4362	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1163	388	A	D	gCc/gAc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,51	deleterious	-4,56	deleterious	-2,85	high_impact	4,8	damaging	0,53	damaging	0,05	deleterious	4,59	24,4	0,1	0,55	disease	0,75	disease	0,95	disease	0,64	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,33	0,8	0,9	4,09	8,05	P	0,66	P	0,89	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7068	7068	A	C	MI.4363	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1165	389	I	L	Atc/Ctc	-8,89	0	0	probably_damaging	0,98	deleterious	0,04	neutral	2,9	neutral	0,32	neutral	-0,99	low_impact	1,75	damaging	0,55	neutral	0,54	deleterious	2,79	21,3	0,33	0,55	neutral	0,22	neutral	0,5	neutral	0,29	neutral	0,42	2	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,63	low_impact	-2,35	medium_impact	-0,58	medium_impact	0,52	0,81	0,9	7,6	8,19	N	0,49	N	0,61	polymorphism	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7068	7068	A	G	MI.4364	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1165	389	I	V	Atc/Gtc	-8,89	0	0	probably_damaging	0,95	neutral	0,06	neutral	2,82	neutral	-0,38	neutral	-0,53	medium_impact	3,08	damaging	0,57	neutral	0,36	deleterious	3,15	22,6	0,5	0,55	neutral	0,3	disease	0,51	neutral	0,35	neutral	0,45	1	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,62	low_impact	-1,96	medium_impact	-0,47	medium_impact	1,75	0,71	0,9	7,6	8,19	N	0,46	N	0,23	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7068	7068	A	T	MI.4365	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1165	389	I	F	Atc/Ttc	-8,89	0	0	probably_damaging	1	deleterious	0,01	neutral	2,83	neutral	-0,29	neutral	-2,08	high_impact	3,92	damaging	0,54	neutral	0,31	deleterious	4	23,6	0,25	0,55	neutral	0,33	disease	0,83	neutral	0,47	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-3,58	medium_impact	-0,92	high_impact	2,52	0,78	0,9	7,6	8,19	N	0,36	N	0,85	disease_causing	0,74	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7069	7069	T	C	MI.4366	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1166	389	I	T	aTc/aCc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-1,35	deleterious	-2,61	medium_impact	3,27	neutral	0,61	neutral	0,34	deleterious	3,54	23,1	0,3	0,55	neutral	0,47	disease	0,74	disease	0,53	disease	0,58	2	deleterious	1	neutral	0	deleterious	5	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	medium_impact	1,92	0,63	0,9	7,6	8,19	P	0,46	N	0,76	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7069	7069	T	A	MI.4367	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1166	389	I	N	aTc/aAc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,69	deleterious	-3,6	deleterious	-3,67	high_impact	4,46	damaging	0,55	neutral	0,36	deleterious	4,5	24,3	0,19	0,55	disease	0,69	disease	0,83	disease	0,56	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,02	0,66	0,9	7,6	8,19	P	0,5	N	0,94	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7069	7069	T	G	MI.4368	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1166	389	I	S	aTc/aGc	7,07	1	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-2,25	deleterious	-3,14	high_impact	3,57	neutral	0,67	neutral	0,42	deleterious	4,41	24,1	0,2	0,55	disease	0,52	disease	0,83	disease	0,56	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	2,2	0,56	0,9	7,6	8,19	N	0,46	N	0,62	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7070	7070	C	A	MI.4369	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1167	389	I	M	atC/atA	5,91	1	0	probably_damaging	1	deleterious	0,01	neutral	2,72	neutral	-1	neutral	-1,53	medium_impact	2,58	damaging	0,58	neutral	0,5	deleterious	3,94	23,6	0,33	0,55	neutral	0,32	disease	0,54	neutral	0,3	neutral	0,43	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,68	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,28	0,8	0,9	7,6	8,19	P	0,49	N	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8731	8731	T	C	MI.437	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	205	69	S	P	Tct/Cct	1,75	0,85	0	probably_damaging	0,99	neutral	0,11	neutral	4,29	neutral	-1,54	deleterious	-3,03	low_impact	0,95	neutral	0,71	damaging	0,14	deleterious	3,84	23,4	0,18	0,65	disease	0,84	disease	0,92	disease	0,71	disease	0,82	6	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,91	low_impact	-2,65	medium_impact	-0,22	medium_impact	-0,28	0,81	0,9	12,39	14,86	N	0,24	N	0,78	polymorphism	0,61	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7070	7070	C	G	MI.4370	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1167	389	I	M	atC/atG	5,91	1	0	probably_damaging	1	deleterious	0,01	neutral	2,72	neutral	-1	neutral	-1,53	medium_impact	2,58	damaging	0,58	neutral	0,5	deleterious	3,42	23	0,33	0,55	neutral	0,32	disease	0,54	neutral	0,3	neutral	0,43	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,68	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,28	0,8	0,9	7,6	8,19	P	0,49	N	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7071	7071	A	C	MI.4371	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1168	390	M	L	Ata/Cta	-4,04	0	0	possibly_damaging	0,84	neutral	0,22	neutral	2,91	neutral	0,33	neutral	-0,45	low_impact	0,86	neutral	0,69	neutral	0,38	deleterious	2,07	16,64	0,31	0,55	neutral	0,18	disease	0,72	neutral	0,37	disease	0,51	0	neutral	0,89	neutral	0,19	neutral	-3	deleterious	0,56	low_impact	-1,43	medium_impact	-0,11	medium_impact	-0,31	0,46	0,9	9,94	14,87	N	0,34	N	0,61	polymorphism	0,74	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7071	7071	A	G	MI.4372	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1168	390	M	V	Ata/Gta	-4,04	0	0	possibly_damaging	0,89	neutral	0,19	neutral	2,76	neutral	-0,28	neutral	-1,09	medium_impact	2,23	neutral	0,69	damaging	0,26	deleterious	2,87	21,7	0,32	0,55	neutral	0,22	disease	0,87	neutral	0,43	disease	0,69	4	neutral	0,94	neutral	0,15	NA	0	deleterious	0,67	low_impact	-1,61	medium_impact	-0,16	medium_impact	0,96	0,51	0,9	9,94	14,87	N	0,33	N	0,88	polymorphism	0,7	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7071	7071	A	T	MI.4373	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1168	390	M	L	Ata/Tta	-4,04	0	0	possibly_damaging	0,84	neutral	0,22	neutral	2,91	neutral	0,33	neutral	-0,45	low_impact	0,86	neutral	0,69	neutral	0,38	deleterious	2,14	17,1	0,31	0,55	neutral	0,18	disease	0,72	neutral	0,37	disease	0,51	0	neutral	0,89	neutral	0,19	neutral	-3	deleterious	0,56	low_impact	-1,43	medium_impact	-0,11	medium_impact	-0,31	0,46	0,9	9,94	14,87	N	0,34	N	0,61	polymorphism	0,74	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7072	7072	T	A	MI.4374	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1169	390	M	K	aTa/aAa	2,67	0,98	0	probably_damaging	0,95	deleterious	0	neutral	2,63	neutral	-2,75	deleterious	-2,51	high_impact	3,82	neutral	0,65	damaging	0,11	deleterious	4,07	23,7	0,16	0,55	disease	0,56	disease	0,94	disease	0,69	disease	0,83	6	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,83	low_impact	-1,96	low_impact	-1,48	high_impact	2,43	0,55	0,9	9,94	14,87	N	0,43	N	0,93	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7072	7072	T	C	MI.4375	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1169	390	M	T	aTa/aCa	2,67	0,98	0	probably_damaging	0,98	deleterious	0	neutral	2,68	neutral	-0,83	neutral	-2,17	medium_impact	3,27	neutral	0,66	damaging	0,17	deleterious	3,09	22,5	0,28	0,55	neutral	0,39	disease	0,85	disease	0,62	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-2,35	low_impact	-1,48	medium_impact	1,92	0,51	0,9	9,94	14,87	N	0,4	N	0,79	disease_causing	0,99	0,05	.	.	.	.	.	.	COSM1138400	.	.	.	.	.	.	.	.
chrM	7073	7073	A	C	MI.4376	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1170	390	M	I	atA/atC	5,91	0,99	0	probably_damaging	0,92	neutral	0,32	neutral	2,77	neutral	-0,14	neutral	-0,81	neutral_impact	0,66	neutral	0,68	neutral	0,6	deleterious	2,38	18,66	0,31	0,55	neutral	0,29	disease	0,85	neutral	0,38	disease	0,53	1	neutral	0,93	neutral	0,2	neutral	-2	deleterious	0,71	low_impact	-1,76	medium_impact	0,01	medium_impact	-0,49	0,55	0,9	9,94	14,87	N	0,47	N	0,87	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7073	7073	A	T	MI.4377	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1170	390	M	I	atA/atT	5,91	0,99	0	probably_damaging	0,92	neutral	0,32	neutral	2,77	neutral	-0,14	neutral	-0,81	neutral_impact	0,66	neutral	0,68	neutral	0,6	deleterious	2,5	19,49	0,31	0,55	neutral	0,29	disease	0,85	neutral	0,38	disease	0,53	1	neutral	0,93	neutral	0,2	neutral	-2	deleterious	0,71	low_impact	-1,76	medium_impact	0,01	medium_impact	-0,49	0,55	0,9	9,94	14,87	N	0,49	N	0,87	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7074	7074	G	T	MI.4378	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1171	391	G	W	Gga/Tga	-1,03	0,01	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-7,5	neutral	-2,2	high_impact	3,81	neutral	0,68	neutral	0,31	deleterious	4,48	24,2	0,12	0,55	disease	0,94	disease	0,93	disease	0,58	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,42	0,52	0,9	7,41	38,69	N	0,32	N	0,71	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7074	7074	G	C	MI.4379	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1171	391	G	R	Gga/Cga	-1,03	0,01	0	probably_damaging	1	deleterious	0,01	neutral	2,47	deleterious	-5,59	neutral	-1,45	medium_impact	3,25	neutral	0,63	damaging	0,28	deleterious	4	23,6	0,1	0,55	disease	0,73	disease	0,95	disease	0,69	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,89	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,9	0,65	0,9	7,41	38,69	N	0,28	N	0,7	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8732	8732	C	A	MI.438	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	206	69	S	Y	tCt/tAt	-0,57	0,15	0	probably_damaging	1	neutral	0,28	neutral	4,28	neutral	-1,05	deleterious	-3,9	low_impact	1,23	neutral	0,88	damaging	0,19	deleterious	4	23,6	0,21	0,65	disease	0,53	disease	0,85	disease	0,64	disease	0,78	6	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,82	low_impact	-3,6	medium_impact	0,06	medium_impact	-0,04	0,75	0,9	12,39	14,86	N	0,35	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7075	7075	G	T	MI.4380	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1172	391	G	V	gGa/gTa	6,14	0,99	0	probably_damaging	1	deleterious	0,01	neutral	2,5	deleterious	-4,09	neutral	-1,23	medium_impact	3	neutral	0,71	neutral	0,47	deleterious	3,81	23,4	0,14	0,55	disease	0,61	disease	0,91	disease	0,57	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,67	0,66	0,9	7,41	38,69	N	0,45	N	0,61	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7075	7075	G	C	MI.4381	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1172	391	G	A	gGa/gCa	6,14	0,99	0	probably_damaging	1	neutral	0,89	neutral	3,16	neutral	0,47	neutral	0,62	neutral_impact	-0,8	neutral	0,7	neutral	0,89	deleterious	0,49	7,37	0,22	0,55	neutral	0,27	neutral	0,17	neutral	0,2	neutral	0,28	4	deleterious	1	neutral	0,45	neutral	-2	deleterious	0,65	low_impact	-3,58	medium_impact	0,7	low_impact	-1,84	0,58	0,9	7,41	38,69	N	0,49	N	0,01	polymorphism	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7075	7075	G	A	MI.4382	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1172	391	G	E	gGa/gAa	6,14	0,99	0	probably_damaging	1	deleterious	0,01	neutral	2,47	deleterious	-5,43	neutral	-1,43	high_impact	3,81	neutral	0,64	neutral	0,35	deleterious	3,99	23,6	0,13	0,55	disease	0,71	disease	0,91	disease	0,68	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,58	medium_impact	-0,92	high_impact	2,42	0,6	0,9	7,41	38,69	N	0,49	N	0,84	polymorphism	0,99	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7077	7077	G	A	MI.4383	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1174	392	G	S	Ggc/Agc	-9,13	0	0	probably_damaging	1	neutral	0,16	neutral	2,64	neutral	-2,78	neutral	-2,48	low_impact	1,87	neutral	0,65	neutral	0,62	deleterious	3,17	22,7	0,28	0,55	neutral	0,32	disease	0,71	neutral	0,47	disease	0,5	0	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,74	low_impact	-3,58	medium_impact	-0,21	medium_impact	0,63	0,73	0,9	2,92	7,5	N	0,37	N	0,73	polymorphism	0,8	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7077	7077	G	T	MI.4384	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1174	392	G	C	Ggc/Tgc	-9,13	0	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-4,85	deleterious	-4,11	high_impact	4,91	damaging	0,59	damaging	0,26	deleterious	4,3	24	0,16	0,55	disease	0,88	disease	0,94	disease	0,67	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,68	0,9	2,92	7,5	P	0,64	P	0,98	disease_causing	0,51	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7077	7077	G	C	MI.4385	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1174	392	G	R	Ggc/Cgc	-9,13	0	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-3,85	deleterious	-3,69	high_impact	4,55	neutral	0,62	damaging	0,23	deleterious	4,07	23,7	0,11	0,55	disease	0,84	disease	0,95	disease	0,77	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,1	0,59	0,9	2,92	7,5	N	0,48	N	0,95	polymorphism	0,65	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7078	7078	G	C	MI.4386	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1175	392	G	A	gGc/gCc	7,53	1	0	probably_damaging	1	neutral	0,15	neutral	2,86	neutral	-0,91	deleterious	-2,55	medium_impact	2,4	neutral	0,62	neutral	0,61	deleterious	2,01	16,26	0,36	0,55	neutral	0,4	disease	0,67	neutral	0,45	neutral	0,47	1	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,75	low_impact	-3,58	medium_impact	-0,23	medium_impact	1,12	0,76	0,9	2,92	7,5	P	0,51	P	0,64	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7078	7078	G	A	MI.4387	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1175	392	G	D	gGc/gAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-4,5	deleterious	-3,21	high_impact	4,91	damaging	0,6	damaging	0,28	deleterious	3,93	23,5	0,12	0,55	disease	0,84	disease	0,91	disease	0,76	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,55	0,9	2,92	7,5	P	0,72	P	0,97	disease_causing	1	0,37	.	.	.	.	.	.	COSM1155669	.	.	.	.	.	.	.	.
chrM	7078	7078	G	T	MI.4388	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1175	392	G	V	gGc/gTc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,69	neutral	-1,64	deleterious	-4,16	high_impact	4,55	neutral	0,69	neutral	0,33	deleterious	3,85	23,4	0,13	0,55	disease	0,76	disease	0,93	disease	0,68	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,1	0,69	0,9	2,92	7,5	P	0,53	P	0,93	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7080	7080	T	G	MI.4389	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1177	393	F	V	Ttc/Gtc	-10,05	0	0	probably_damaging	1	neutral	0,12	neutral	2,85	neutral	0,43	neutral	-1,46	low_impact	1,36	neutral	0,61	neutral	0,62	deleterious	2,78	21,3	0,32	0,55	neutral	0,24	disease	0,87	neutral	0,43	disease	0,52	0	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	-0,29	medium_impact	0,16	0,61	0,9	6,43	9,35	N	0,42	N	0,84	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8732	8732	C	G	MI.439	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	206	69	S	C	tCt/tGt	-0,57	0,15	0	probably_damaging	1	neutral	0,11	neutral	4,27	neutral	-2,2	deleterious	-2,61	low_impact	1,92	neutral	0,87	damaging	0,2	deleterious	3,43	23	0,27	0,65	disease	0,82	disease	0,81	neutral	0,43	disease	0,74	5	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,82	low_impact	-3,6	medium_impact	-0,22	medium_impact	0,55	0,77	0,9	12,39	14,86	N	0,34	N	0,51	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7080	7080	T	C	MI.4390	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1177	393	F	L	Ttc/Ctc	-10,05	0	0	probably_damaging	0,99	neutral	0,16	neutral	2,9	neutral	0,79	neutral	-1,12	low_impact	0,96	neutral	0,61	neutral	0,71	deleterious	0,89	9,99	0,38	0,55	neutral	0,28	disease	0,66	neutral	0,39	neutral	0,48	0	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,7	low_impact	-2,64	medium_impact	-0,21	medium_impact	-0,21	0,66	0,9	6,43	9,35	N	0,43	N	0,83	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	1,19	T7080C	Prostate Cancer	+	-	Reported	1
chrM	7080	7080	T	A	MI.4391	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1177	393	F	I	Ttc/Atc	-10,05	0	0	probably_damaging	1	neutral	0,22	neutral	3,02	neutral	1,42	neutral	-1,04	low_impact	1,02	damaging	0,58	neutral	0,75	neutral	1,51	13,37	0,22	0,55	neutral	0,34	disease	0,76	neutral	0,38	disease	0,52	0	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,73	low_impact	-3,58	medium_impact	-0,11	medium_impact	-0,16	0,61	0,9	6,43	9,35	N	0,43	N	0,88	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7081	7081	T	G	MI.4392	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1178	393	F	C	tTc/tGc	3,14	0,99	0	probably_damaging	1	deleterious	0	neutral	2,68	deleterious	-3,1	neutral	-2,45	high_impact	4,04	damaging	0,6	neutral	0,51	deleterious	4,19	23,8	0,25	0,55	disease	0,73	disease	0,91	disease	0,61	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,63	0,41	0,9	6,43	9,35	N	0,41	N	0,91	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7081	7081	T	A	MI.4393	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1178	393	F	Y	tTc/tAc	3,14	0,99	0	probably_damaging	0,99	neutral	0,07	neutral	2,73	neutral	-1,09	neutral	-1,05	medium_impact	2,9	neutral	0,66	neutral	0,5	deleterious	4,04	23,7	0,31	0,55	disease	0,53	disease	0,81	neutral	0,4	disease	0,53	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,76	low_impact	-2,64	medium_impact	-0,43	medium_impact	1,58	0,65	0,9	6,43	9,35	P	0,52	P	0,59	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7081	7081	T	C	MI.4394	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1178	393	F	S	tTc/tCc	3,14	0,99	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-1,66	deleterious	-2,6	high_impact	3,68	neutral	0,71	neutral	0,58	deleterious	4,29	24	0,32	0,55	neutral	0,4	disease	0,84	disease	0,59	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,3	0,55	0,9	6,43	9,35	N	0,44	N	0,84	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7082	7082	C	A	MI.4395	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1179	393	F	L	ttC/ttA	7,53	1	0	probably_damaging	0,99	neutral	0,16	neutral	2,9	neutral	0,79	neutral	-1,12	low_impact	0,96	neutral	0,61	neutral	0,71	neutral	1,48	13,2	0,38	0,55	neutral	0,28	disease	0,66	neutral	0,39	neutral	0,48	0	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,7	low_impact	-2,64	medium_impact	-0,21	medium_impact	-0,21	0,66	0,9	6,43	9,35	P	0,6	P	0,83	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7082	7082	C	G	MI.4396	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1179	393	F	L	ttC/ttG	7,53	1	0	probably_damaging	0,99	neutral	0,16	neutral	2,9	neutral	0,79	neutral	-1,12	low_impact	0,96	neutral	0,61	neutral	0,71	neutral	1,12	11,31	0,38	0,55	neutral	0,28	disease	0,66	neutral	0,39	neutral	0,48	0	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,7	low_impact	-2,64	medium_impact	-0,21	medium_impact	-0,21	0,66	0,9	6,43	9,35	P	0,56	P	0,83	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7083	7083	A	T	MI.4397	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1180	394	I	F	Att/Ttt	-3,11	0	0	benign	0,22	deleterious	0,03	neutral	2,8	neutral	-0,16	neutral	-1,48	medium_impact	2,08	neutral	0,61	neutral	0,46	neutral	0,99	10,61	0,44	0,55	neutral	0,33	disease	0,8	neutral	0,3	disease	0,66	3	neutral	0,97	neutral	0,41	deleterious	1	neutral	0,3	medium_impact	-0,24	medium_impact	-0,65	medium_impact	0,82	0,65	0,9	13,65	40,83	N	0,41	N	0,37	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7083	7083	A	C	MI.4398	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1180	394	I	L	Att/Ctt	-3,11	0	0	benign	0,01	neutral	0,07	neutral	2,89	neutral	0,88	neutral	-0,66	medium_impact	2	neutral	0,72	neutral	0,51	deleterious	0,88	9,96	0,35	0,55	neutral	0,19	disease	0,64	neutral	0,38	disease	0,51	0	neutral	0,93	deleterious	0,53	neutral	-3	neutral	0,11	medium_impact	1,12	medium_impact	-0,43	medium_impact	0,75	0,55	0,9	13,65	40,83	N	0,46	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7083	7083	A	G	MI.4399	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1180	394	I	V	Att/Gtt	-3,11	0	0	benign	0	neutral	1	neutral	2,81	neutral	0	neutral	0,06	low_impact	1,04	neutral	0,86	neutral	0,99	neutral	-1,16	0,01	0,57	0,6	neutral	0,19	neutral	0,21	neutral	0,29	neutral	0,36	3	neutral	0	deleterious	1	neutral	-6	neutral	0,07	high_impact	2,07	high_impact	1,86	medium_impact	-0,14	0,65	0,9	13,65	40,83	N	0,41	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	75,22	A7083G	Prostate Cancer	+	-	Reported	1
chrM	8545	8545	G	A	MI.44	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	19	7	A	T	Gct/Act	-1,03	0	0,01	benign	0	neutral	0,07	neutral	4,67	neutral	-0,68	neutral	0,22	low_impact	0,8	neutral	1	neutral	0,96	deleterious	0,75	9,13	0,54	0,65	neutral	0,41	neutral	0,32	neutral	0,26	neutral	0,47	1	neutral	0,93	deleterious	0,54	neutral	-6	neutral	0,13	high_impact	2,09	medium_impact	-0,34	medium_impact	-0,41	0,61	0,9	9,29	10,06	P	0,51	P	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8732	8732	C	T	MI.440	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	206	69	S	F	tCt/tTt	-0,57	0,15	0	probably_damaging	1	neutral	0,41	neutral	4,38	neutral	1,32	deleterious	-3,9	neutral_impact	-0,04	neutral	0,77	damaging	0,16	deleterious	4,02	23,6	0,28	0,65	neutral	0,3	disease	0,84	disease	0,62	disease	0,59	2	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,76	low_impact	-3,6	medium_impact	0,2	low_impact	-1,13	0,64	0,9	12,39	14,86	N	0,25	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7084	7084	T	G	MI.4400	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1181	394	I	S	aTt/aGt	1,05	0,46	0	benign	0,09	neutral	0,12	neutral	2,8	neutral	-0,15	neutral	-1,44	medium_impact	2,22	neutral	0,62	neutral	0,55	neutral	1,44	13,02	0,33	0,55	neutral	0,34	disease	0,75	neutral	0,45	disease	0,54	1	neutral	0,87	deleterious	0,52	neutral	-3	neutral	0,2	medium_impact	0,19	medium_impact	-0,29	medium_impact	0,95	0,63	0,9	13,65	40,83	N	0,38	N	0,23	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7084	7084	T	A	MI.4401	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1181	394	I	N	aTt/aAt	1,05	0,46	0	possibly_damaging	0,46	neutral	0,1	neutral	2,72	neutral	-2,08	neutral	-1,95	low_impact	1,92	neutral	0,71	neutral	0,61	neutral	1,47	13,17	0,36	0,55	disease	0,59	disease	0,79	neutral	0,32	disease	0,55	1	neutral	0,89	neutral	0,32	neutral	-3	deleterious	0,54	medium_impact	-0,69	medium_impact	-0,34	medium_impact	0,67	0,7	0,9	13,65	40,83	N	0,33	N	0,44	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7084	7084	T	C	MI.4402	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1181	394	I	T	aTt/aCt	1,05	0,46	0	benign	0,09	neutral	0,48	neutral	2,78	neutral	-0,36	neutral	-0,55	low_impact	1,06	neutral	0,72	neutral	0,92	neutral	-0,74	0,06	0,43	0,55	neutral	0,25	neutral	0,44	neutral	0,31	neutral	0,45	1	neutral	0,45	deleterious	0,7	neutral	-6	neutral	0,16	medium_impact	0,19	medium_impact	0,17	medium_impact	-0,12	0,68	0,9	13,65	40,83	N	0,34	N	0,25	polymorphism	1	0,02	rs28445709	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7085	7085	T	G	MI.4403	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1182	394	I	M	atT/atG	2,9	0,52	0,01	benign	0,02	deleterious	0,02	neutral	2,74	neutral	-1,45	neutral	-0,84	medium_impact	3,12	neutral	0,73	neutral	0,81	neutral	1,54	13,51	0,48	0,55	neutral	0,42	neutral	0,49	neutral	0,31	disease	0,5	0	neutral	0,98	deleterious	0,5	deleterious	1	neutral	0,13	medium_impact	0,83	medium_impact	-0,75	medium_impact	1,78	0,76	0,9	13,65	40,83	N	0,44	N	0	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7085	7085	T	A	MI.4404	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1182	394	I	M	atT/atA	2,9	0,52	0,01	benign	0,02	deleterious	0,02	neutral	2,74	neutral	-1,45	neutral	-0,84	medium_impact	3,12	neutral	0,73	neutral	0,81	deleterious	1,8	15,01	0,48	0,55	neutral	0,42	neutral	0,49	neutral	0,31	disease	0,5	0	neutral	0,98	deleterious	0,5	deleterious	1	neutral	0,13	medium_impact	0,83	medium_impact	-0,75	medium_impact	1,78	0,76	0,9	13,65	40,83	N	0,45	N	0	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7086	7086	C	A	MI.4405	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1183	395	H	N	Cac/Aac	-8,89	0	0	probably_damaging	1	deleterious	0,04	neutral	2,76	neutral	-1,71	deleterious	-2,69	medium_impact	2,36	damaging	0,54	damaging	0,07	deleterious	2,89	21,8	0,54	0,6	disease	0,87	disease	0,86	disease	0,52	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,85	low_impact	-3,58	medium_impact	-0,58	medium_impact	1,08	0,58	0,9	2,34	6,69	N	0,22	N	0,86	polymorphism	0,94	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7086	7086	C	T	MI.4406	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1183	395	H	Y	Cac/Tac	-8,89	0	0	probably_damaging	1	neutral	0,25	neutral	3,1	neutral	2,54	neutral	-1,19	neutral_impact	0,72	damaging	0,43	damaging	0,04	deleterious	2,56	19,84	0,62	0,65	neutral	0,16	disease	0,61	neutral	0,41	neutral	0,42	2	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	-0,07	medium_impact	-0,43	0,35	0,9	2,34	6,69	N	0,31	N	0,72	polymorphism	0,93	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7086	7086	C	G	MI.4407	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1183	395	H	D	Cac/Gac	-8,89	0	0	probably_damaging	1	deleterious	0,01	neutral	2,79	neutral	-0,52	deleterious	-3,48	high_impact	4,31	damaging	0,5	damaging	0,04	deleterious	3,97	23,6	0,26	0,55	disease	0,93	disease	0,89	disease	0,73	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,58	medium_impact	-0,92	high_impact	2,88	0,57	0,9	2,34	6,69	N	0,35	N	0,97	polymorphism	0,83	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7087	7087	A	T	MI.4408	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1184	395	H	L	cAc/cTc	7,3	1	0	probably_damaging	1	neutral	0,27	neutral	2,9	neutral	1,3	deleterious	-3,97	medium_impact	2,89	damaging	0,53	damaging	0,03	deleterious	3,89	23,5	0,35	0,55	disease	0,58	disease	0,91	disease	0,51	disease	0,55	1	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,84	low_impact	-3,58	medium_impact	-0,05	medium_impact	1,57	0,46	0,9	2,34	6,69	N	0,47	N	0,92	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7087	7087	A	C	MI.4409	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1184	395	H	P	cAc/cCc	7,3	1	0	probably_damaging	1	deleterious	0,01	neutral	2,75	neutral	-2,23	deleterious	-3,9	high_impact	4,31	damaging	0,48	damaging	0,04	deleterious	3,31	22,9	0,3	0,55	disease	0,93	disease	0,95	disease	0,76	disease	0,87	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,91	low_impact	-3,58	medium_impact	-0,92	high_impact	2,88	0,5	0,9	2,34	6,69	P	0,55	P	0,9	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8734	8734	C	G	MI.441	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	208	70	L	V	Ctt/Gtt	-16,07	0	0	probably_damaging	0,99	neutral	0,33	neutral	3,79	neutral	-0,63	neutral	-2,19	low_impact	1,41	neutral	0,8	neutral	0,57	deleterious	2,23	17,73	0,48	0,65	neutral	0,32	neutral	0,48	neutral	0,34	neutral	0,46	1	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,71	low_impact	-2,65	medium_impact	0,12	medium_impact	0,11	0,81	0,9	49,12	8,68	N	0,32	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7087	7087	A	G	MI.4410	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1184	395	H	R	cAc/cGc	7,3	1	0	probably_damaging	1	deleterious	0,02	neutral	2,76	neutral	-1,49	deleterious	-3,01	high_impact	4,31	damaging	0,56	damaging	0,04	deleterious	3,1	22,5	0,58	0,65	disease	0,9	disease	0,92	disease	0,69	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-3,58	medium_impact	-0,75	high_impact	2,88	0,55	0,9	2,34	6,69	P	0,48	N	0,85	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7088	7088	C	G	MI.4411	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1185	395	H	Q	caC/caG	8,69	1	0	probably_damaging	1	neutral	0,07	neutral	2,76	neutral	-1,57	deleterious	-2,66	low_impact	1,46	damaging	0,47	damaging	0,06	deleterious	2,29	18,08	0,61	0,65	disease	0,88	disease	0,54	neutral	0,48	disease	0,64	3	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,81	low_impact	-3,58	medium_impact	-0,43	medium_impact	0,25	0,59	0,9	2,34	6,69	P	0,52	P	0,83	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7088	7088	C	A	MI.4412	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1185	395	H	Q	caC/caA	8,69	1	0	probably_damaging	1	neutral	0,07	neutral	2,76	neutral	-1,57	deleterious	-2,66	low_impact	1,46	damaging	0,47	damaging	0,06	deleterious	2,55	19,78	0,61	0,65	disease	0,88	disease	0,54	neutral	0,48	disease	0,64	3	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,81	low_impact	-3,58	medium_impact	-0,43	medium_impact	0,25	0,59	0,9	2,34	6,69	P	0,52	P	0,83	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7089	7089	T	G	MI.4413	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1186	396	W	G	Tga/Gga	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-5,18	deleterious	-6,71	high_impact	5,05	neutral	0,6	damaging	0,04	deleterious	3,98	23,6	0,18	0,55	disease	0,93	disease	0,88	disease	0,78	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,19	0,9	2,34	6,59	P	0,6	P	0,89	disease_causing	0,99	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7089	7089	T	C	MI.4414	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1186	396	W	R	Tga/Cga	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-5,08	deleterious	-7,21	high_impact	4,36	damaging	0,57	damaging	0,03	deleterious	3,69	23,3	0,21	0,55	disease	0,92	disease	0,95	disease	0,81	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	2,93	0,19	0,9	2,34	6,59	N	0,41	N	0,98	disease_causing	0,98	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7090	7090	G	T	MI.4415	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1187	396	W	L	tGa/tTa	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-1,56	deleterious	-6,68	high_impact	4,36	neutral	0,64	damaging	0,03	deleterious	4,37	24,1	0,15	0,55	disease	0,72	disease	0,9	disease	0,75	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,93	0,18	0,9	2,34	6,59	P	0,53	P	0,95	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7090	7090	G	C	MI.4416	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1187	396	W	S	tGa/tCa	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,59	deleterious	-4,09	deleterious	-7,21	high_impact	4,7	damaging	0,59	damaging	0,03	deleterious	4,17	23,8	0,19	0,55	disease	0,89	disease	0,91	disease	0,76	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,24	0,16	0,9	2,34	6,59	P	0,57	P	0,89	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7091	7091	A	T	MI.4417	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1188	396	W	C	tgA/tgT	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-5,43	deleterious	-6,7	high_impact	4,5	damaging	0,53	damaging	0,03	deleterious	4,22	23,9	0,22	0,55	disease	0,95	disease	0,93	disease	0,79	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,2	0,9	2,34	6,59	P	0,5	N	0,88	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7091	7091	A	C	MI.4418	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1188	396	W	C	tgA/tgC	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-5,43	deleterious	-6,7	high_impact	4,5	damaging	0,53	damaging	0,03	deleterious	4,14	23,8	0,22	0,55	disease	0,95	disease	0,93	disease	0,79	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,06	0,2	0,9	2,34	6,59	P	0,5	N	0,88	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7092	7092	T	C	MI.4419	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1189	397	F	L	Ttt/Ctt	5,91	1	0	probably_damaging	1	neutral	0,07	neutral	2,81	neutral	0,02	deleterious	-2,55	medium_impact	2,23	damaging	0,54	damaging	0,05	deleterious	4,25	23,9	0,25	0,55	neutral	0,28	disease	0,85	neutral	0,44	disease	0,66	3	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,74	low_impact	-3,58	medium_impact	-0,43	medium_impact	0,96	0,75	0,9	3,12	6,64	P	0,48	N	0,83	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8734	8734	C	A	MI.442	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	208	70	L	I	Ctt/Att	-16,07	0	0	probably_damaging	0,99	neutral	0,42	neutral	3,76	neutral	-1,13	neutral	-1,47	low_impact	1,36	neutral	0,84	neutral	0,62	deleterious	3,99	23,6	0,41	0,65	neutral	0,47	disease	0,52	neutral	0,31	neutral	0,47	1	deleterious	0,99	neutral	0,22	neutral	-2	deleterious	0,74	low_impact	-2,65	medium_impact	0,21	medium_impact	0,07	0,75	0,9	49,12	8,68	N	0,28	N	0,87	polymorphism	1	0,02	rs878902140	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7092	7092	T	G	MI.4420	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1189	397	F	V	Ttt/Gtt	5,91	1	0	probably_damaging	1	deleterious	0,01	neutral	2,79	neutral	-0,16	deleterious	-2,85	medium_impact	2,79	damaging	0,52	damaging	0,06	deleterious	4,23	23,9	0,28	0,55	neutral	0,2	disease	0,89	neutral	0,49	disease	0,53	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,72	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,48	0,49	0,9	3,12	6,64	N	0,39	N	0,84	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7092	7092	T	A	MI.4421	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1189	397	F	I	Ttt/Att	5,91	1	0	probably_damaging	1	deleterious	0,01	neutral	2,75	neutral	-0,43	deleterious	-2,53	medium_impact	2,9	damaging	0,57	damaging	0,07	deleterious	4,58	24,4	0,21	0,55	neutral	0,33	disease	0,83	neutral	0,25	neutral	0,48	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,58	0,54	0,9	3,12	6,64	N	0,47	N	0,88	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7093	7093	T	C	MI.4422	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1190	397	F	S	tTt/tCt	7,53	1	0	probably_damaging	1	deleterious	0,02	neutral	2,65	neutral	-1,94	deleterious	-3,38	medium_impact	2,3	damaging	0,55	damaging	0,08	deleterious	4,47	24,2	0,31	0,55	neutral	0,37	disease	0,84	neutral	0,38	disease	0,54	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,77	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,03	0,5	0,9	3,12	6,64	N	0,41	N	0,84	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7093	7093	T	G	MI.4423	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1190	397	F	C	tTt/tGt	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-3,78	deleterious	-3,41	high_impact	3,82	damaging	0,53	damaging	0,05	deleterious	4,33	24	0,23	0,55	disease	0,66	disease	0,92	neutral	0,47	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,43	0,3	0,9	3,12	6,64	N	0,42	N	0,91	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7093	7093	T	A	MI.4424	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1190	397	F	Y	tTt/tAt	7,53	1	0	probably_damaging	1	neutral	0,23	neutral	2,64	neutral	-2,1	neutral	-0,27	neutral_impact	0,48	damaging	0,52	damaging	0,1	deleterious	2,85	21,6	0,3	0,55	neutral	0,26	neutral	0,42	neutral	0,2	neutral	0,44	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	-0,1	medium_impact	-0,66	0,59	0,9	3,12	6,64	P	0,59	P	0,59	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7094	7094	T	A	MI.4425	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1191	397	F	L	ttT/ttA	7,53	1	0,01	probably_damaging	1	neutral	0,07	neutral	2,81	neutral	0,02	deleterious	-2,55	medium_impact	2,23	damaging	0,54	damaging	0,05	deleterious	4,57	24,4	0,25	0,55	neutral	0,28	disease	0,85	neutral	0,44	disease	0,66	3	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,74	low_impact	-3,58	medium_impact	-0,43	medium_impact	0,96	0,75	0,9	3,12	6,64	P	0,5	N	0,83	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7094	7094	T	G	MI.4426	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1191	397	F	L	ttT/ttG	7,53	1	0,01	probably_damaging	1	neutral	0,07	neutral	2,81	neutral	0,02	deleterious	-2,55	medium_impact	2,23	damaging	0,54	damaging	0,05	deleterious	4,45	24,2	0,25	0,55	neutral	0,28	disease	0,85	neutral	0,44	disease	0,66	3	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,74	low_impact	-3,58	medium_impact	-0,43	medium_impact	0,96	0,75	0,9	3,12	6,64	P	0,49	N	0,83	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7095	7095	C	T	MI.4427	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1192	398	P	S	Ccc/Tcc	-1,03	0,01	0	probably_damaging	1	neutral	0,11	neutral	2,18	deleterious	-3,54	deleterious	-4,01	medium_impact	3,44	neutral	0,64	damaging	0,05	deleterious	3,97	23,6	0,39	0,55	neutral	0,34	disease	0,79	neutral	0,3	disease	0,51	0	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,76	low_impact	-3,58	medium_impact	-0,31	high_impact	2,08	0,34	0,9	2,92	6,75	N	0,31	N	0,85	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7095	7095	C	A	MI.4428	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1192	398	P	T	Ccc/Acc	-1,03	0,01	0	probably_damaging	1	deleterious	0	neutral	2,15	deleterious	-4,39	deleterious	-4,04	high_impact	3,81	neutral	0,64	damaging	0,05	deleterious	3,8	23,4	0,28	0,55	disease	0,56	disease	0,84	disease	0,56	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,42	0,8	0,9	2,92	6,75	N	0,29	N	0,8	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7095	7095	C	G	MI.4429	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1192	398	P	A	Ccc/Gcc	-1,03	0,01	0	probably_damaging	1	deleterious	0	neutral	2,16	deleterious	-4,04	deleterious	-4,04	high_impact	3,92	neutral	0,66	damaging	0,06	deleterious	3,22	22,7	0,25	0,55	disease	0,51	disease	0,77	disease	0,59	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,52	0,76	0,9	2,92	6,75	N	0,3	N	0,76	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8734	8734	C	T	MI.443	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	208	70	L	F	Ctt/Ttt	-16,07	0	0	probably_damaging	1	neutral	0,48	neutral	3,75	neutral	-1,69	deleterious	-2,83	low_impact	1,76	neutral	0,79	neutral	0,46	deleterious	2,79	21,3	0,42	0,65	disease	0,65	neutral	0,48	neutral	0,36	disease	0,58	2	deleterious	0,99	neutral	0,24	neutral	-2	deleterious	0,77	low_impact	-3,6	medium_impact	0,27	medium_impact	0,41	0,73	0,9	49,12	8,68	N	0,25	N	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7096	7096	C	G	MI.4430	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1193	398	P	R	cCc/cGc	4,52	0,99	0	probably_damaging	1	deleterious	0	neutral	2,3	neutral	-2,1	deleterious	-4,57	high_impact	4,07	neutral	0,63	damaging	0,03	deleterious	3,76	23,3	0,21	0,55	disease	0,57	disease	0,94	disease	0,72	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,66	0,73	0,9	2,92	6,75	N	0,41	N	0,9	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7096	7096	C	T	MI.4431	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1193	398	P	L	cCc/cTc	4,52	0,99	0	probably_damaging	1	deleterious	0	neutral	2,13	deleterious	-5,11	deleterious	-5,1	high_impact	4,41	neutral	0,67	damaging	0,02	deleterious	4,53	24,3	0,28	0,55	disease	0,67	disease	0,91	disease	0,56	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,97	0,82	0,9	2,92	6,75	N	0,44	N	0,87	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7096	7096	C	A	MI.4432	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1193	398	P	H	cCc/cAc	4,52	0,99	0	probably_damaging	1	deleterious	0,01	neutral	2,13	deleterious	-5,35	deleterious	-4,57	high_impact	4,62	neutral	0,66	damaging	0,02	deleterious	4,11	23,7	0,25	0,55	neutral	0,32	disease	0,9	disease	0,6	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-3,58	medium_impact	-0,92	high_impact	3,17	0,7	0,9	2,92	6,75	N	0,41	N	0,81	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7098	7098	C	G	MI.4433	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1195	399	L	V	Cta/Gta	-14,22	0	0	probably_damaging	0,98	neutral	0,05	neutral	2,76	neutral	-1,1	neutral	-1,31	medium_impact	2,22	damaging	0,5	damaging	0,04	deleterious	3,5	23,1	0,43	0,55	neutral	0,33	disease	0,66	neutral	0,19	neutral	0,43	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,71	low_impact	-2,35	medium_impact	-0,52	medium_impact	0,95	0,57	0,9	2,34	6,71	N	0,39	N	0,66	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7098	7098	C	A	MI.4434	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1195	399	L	M	Cta/Ata	-14,22	0	0	probably_damaging	1	neutral	0,08	neutral	2,71	neutral	-1,42	neutral	-0,85	medium_impact	2,35	damaging	0,54	damaging	0,06	deleterious	3,82	23,4	0,27	0,55	disease	0,5	disease	0,53	neutral	0,18	neutral	0,43	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,71	low_impact	-3,58	medium_impact	-0,4	medium_impact	1,07	0,74	0,9	2,34	6,71	N	0,38	N	0,59	polymorphism	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7099	7099	T	G	MI.4435	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1196	399	L	R	cTa/cGa	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,84	neutral	-0,66	deleterious	-2,96	high_impact	4,65	damaging	0,52	damaging	0,03	deleterious	4,33	24	0,24	0,55	neutral	0,48	disease	0,93	disease	0,58	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,2	0,71	0,9	2,34	6,71	N	0,43	N	0,9	polymorphism	0,82	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7099	7099	T	A	MI.4436	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1196	399	L	Q	cTa/cAa	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-0,16	deleterious	-2,92	high_impact	4,3	damaging	0,54	damaging	0,03	deleterious	4,2	23,9	0,22	0,55	neutral	0,44	disease	0,82	neutral	0,43	disease	0,65	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	2,87	0,62	0,9	2,34	6,71	N	0,34	N	0,82	polymorphism	0,85	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7099	7099	T	C	MI.4437	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1196	399	L	P	cTa/cCa	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-2,2	deleterious	-3,43	high_impact	3,96	damaging	0,42	damaging	0,03	deleterious	4,04	23,7	0,18	0,55	disease	0,64	disease	0,89	disease	0,69	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,56	0,43	0,9	2,34	6,71	N	0,39	N	0,83	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7101	7101	T	C	MI.4438	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1198	400	F	L	Ttc/Ctc	-0,57	0,17	0	probably_damaging	1	neutral	0,22	neutral	3,02	neutral	1,61	neutral	-1,95	low_impact	1,68	neutral	0,67	neutral	0,45	neutral	1	10,66	0,31	0,55	neutral	0,16	disease	0,76	neutral	0,23	neutral	0,48	0	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	-0,11	medium_impact	0,45	0,73	0,9	6,82	9,8	N	0,39	N	0,83	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7101	7101	T	A	MI.4439	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1198	400	F	I	Ttc/Atc	-0,57	0,17	0	probably_damaging	1	neutral	0,4	neutral	2,88	neutral	0,93	neutral	-1,98	low_impact	0,95	neutral	0,67	damaging	0,28	neutral	1,62	13,96	0,23	0,55	neutral	0,2	disease	0,5	neutral	0,17	neutral	0,41	2	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	0,1	medium_impact	-0,22	0,45	0,9	6,82	9,8	N	0,41	N	0,88	disease_causing	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8735	8735	T	G	MI.444	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	209	70	L	R	cTt/cGt	-1,26	0	0	probably_damaging	1	neutral	0,17	neutral	3,72	neutral	-1,64	deleterious	-4,71	medium_impact	3,32	neutral	0,77	neutral	0,41	deleterious	4	23,6	0,15	0,65	disease	0,71	disease	0,84	disease	0,54	disease	0,59	2	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	-0,1	medium_impact	1,75	0,78	0,9	49,12	8,68	N	0,31	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7101	7101	T	G	MI.4440	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1198	400	F	V	Ttc/Gtc	-0,57	0,17	0	probably_damaging	1	deleterious	0,04	neutral	2,92	neutral	0,92	neutral	-2,46	medium_impact	2,92	neutral	0,63	damaging	0,15	deleterious	3,82	23,4	0,34	0,55	neutral	0,19	disease	0,86	neutral	0,28	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,72	low_impact	-3,58	medium_impact	-0,58	medium_impact	1,6	0,49	0,9	6,82	9,8	N	0,33	N	0,84	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7102	7102	T	A	MI.4441	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1199	400	F	Y	tTc/tAc	3,83	1	0	probably_damaging	1	deleterious	0	neutral	2,75	neutral	-1,39	neutral	-1,29	high_impact	3,56	neutral	0,67	damaging	0,15	deleterious	4,26	23,9	0,35	0,55	disease	0,51	disease	0,81	neutral	0,44	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	2,19	0,59	0,9	6,82	9,8	P	0,48	N	0,59	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7102	7102	T	G	MI.4442	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1199	400	F	C	tTc/tGc	3,83	1	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,45	deleterious	-3,22	high_impact	4,45	neutral	0,64	damaging	0,14	deleterious	4,18	23,8	0,25	0,55	disease	0,63	disease	0,91	disease	0,59	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,01	0,31	0,9	6,82	9,8	N	0,46	N	0,91	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7102	7102	T	C	MI.4443	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1199	400	F	S	tTc/tCc	3,83	1	0	probably_damaging	1	deleterious	0	neutral	2,75	neutral	-0,89	deleterious	-3,32	high_impact	4,45	neutral	0,69	damaging	0,16	deleterious	4,38	24,1	0,29	0,55	neutral	0,43	disease	0,83	disease	0,58	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,01	0,4	0,9	6,82	9,8	N	0,47	N	0,84	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7103	7103	C	G	MI.4444	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1200	400	F	L	ttC/ttG	7,53	1	0	probably_damaging	1	neutral	0,22	neutral	3,02	neutral	1,61	neutral	-1,95	low_impact	1,68	neutral	0,67	neutral	0,45	neutral	1,36	12,59	0,31	0,55	neutral	0,16	disease	0,76	neutral	0,23	neutral	0,48	0	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	-0,11	medium_impact	0,45	0,73	0,9	6,82	9,8	P	0,51	P	0,83	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7103	7103	C	A	MI.4445	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1200	400	F	L	ttC/ttA	7,53	1	0	probably_damaging	1	neutral	0,22	neutral	3,02	neutral	1,61	neutral	-1,95	low_impact	1,68	neutral	0,67	neutral	0,45	neutral	1,6	13,83	0,31	0,55	neutral	0,16	disease	0,76	neutral	0,23	neutral	0,48	0	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	-0,11	medium_impact	0,45	0,73	0,9	6,82	9,8	P	0,54	P	0,83	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7104	7104	T	A	MI.4446	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1201	401	S	T	Tca/Aca	-4,5	0	0	benign	0,01	neutral	1	neutral	3,22	neutral	2,01	neutral	1,04	neutral_impact	-1,96	neutral	0,73	neutral	0,95	neutral	1,09	11,17	0,35	0,55	neutral	0,24	neutral	0,07	neutral	0,13	neutral	0,25	5	neutral	0,01	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,12	high_impact	1,86	low_impact	-2,91	0,81	0,9	9,16	26,09	N	0,43	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7104	7104	T	G	MI.4447	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1201	401	S	A	Tca/Gca	-4,5	0	0	benign	0,24	deleterious	0,01	neutral	2,97	neutral	-0,26	neutral	-0,5	medium_impact	2,15	neutral	0,64	damaging	0,25	deleterious	3,78	23,4	0,34	0,55	neutral	0,25	disease	0,56	neutral	0,35	neutral	0,49	0	deleterious	0,99	neutral	0,39	deleterious	1	neutral	0,21	medium_impact	-0,29	medium_impact	-0,92	medium_impact	0,89	0,64	0,9	9,16	26,09	N	0,4	N	0,09	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7104	7104	T	C	MI.4448	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1201	401	S	P	Tca/Cca	-4,5	0	0	possibly_damaging	0,73	deleterious	0	neutral	2,93	neutral	-2,05	neutral	-1,22	medium_impact	2,36	damaging	0,56	damaging	0,12	deleterious	4,08	23,7	0,19	0,55	disease	0,51	disease	0,91	neutral	0,44	disease	0,78	6	deleterious	1	neutral	0,14	deleterious	4	deleterious	0,69	low_impact	-1,16	low_impact	-1,48	medium_impact	1,08	0,58	0,9	9,16	26,09	N	0,32	N	0,62	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7105	7105	C	T	MI.4449	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1202	401	S	L	tCa/tTa	-0,33	0	0	probably_damaging	0,93	neutral	0,08	neutral	3,05	neutral	0,23	neutral	-0,72	neutral_impact	0,66	neutral	0,67	damaging	0,18	deleterious	3,66	23,2	0,24	0,55	neutral	0,24	disease	0,78	neutral	0,23	neutral	0,5	0	deleterious	0,98	neutral	0,08	neutral	-2	deleterious	0,67	low_impact	-1,81	medium_impact	-0,4	medium_impact	-0,49	0,84	0,9	9,16	26,09	N	0,36	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8735	8735	T	A	MI.445	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	209	70	L	H	cTt/cAt	-1,26	0	0	probably_damaging	1	neutral	0,33	neutral	3,72	neutral	-2,8	deleterious	-5,47	medium_impact	3,12	neutral	0,76	neutral	0,3	deleterious	3,93	23,5	0,21	0,65	neutral	0,48	disease	0,78	neutral	0,48	disease	0,62	2	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	0,12	medium_impact	1,58	0,69	0,9	49,12	8,68	N	0,3	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7105	7105	C	G	MI.4450	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1202	401	S	W	tCa/tGa	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	2,96	deleterious	-3,38	neutral	-1,15	medium_impact	2,7	neutral	0,64	damaging	0,14	deleterious	4,49	24,3	0,18	0,55	disease	0,75	disease	0,91	neutral	0,47	disease	0,75	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	medium_impact	1,39	0,54	0,9	9,16	26,09	N	0,29	N	0,78	polymorphism	0,56	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7107	7107	G	C	MI.4451	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1204	402	G	R	Ggc/Cgc	-0,57	0,06	0	probably_damaging	1	deleterious	0	neutral	2,41	deleterious	-3,5	deleterious	-3,92	high_impact	4,67	damaging	0,46	damaging	0,03	deleterious	4,11	23,7	0,18	0,55	disease	0,89	disease	0,92	disease	0,81	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,21	0,87	0,9	1,75	6,75	P	0,61	P	0,95	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7107	7107	G	T	MI.4452	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1204	402	G	C	Ggc/Tgc	-0,57	0,06	0	probably_damaging	1	deleterious	0	neutral	2,34	deleterious	-7,27	deleterious	-4,49	high_impact	5,01	damaging	0,41	damaging	0,03	deleterious	4,27	24	0,15	0,55	disease	0,91	disease	0,92	disease	0,62	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,53	0,54	0,9	1,75	6,75	P	0,52	P	0,98	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7107	7107	G	A	MI.4453	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1204	402	G	S	Ggc/Agc	-0,57	0,06	0	probably_damaging	1	deleterious	0,01	neutral	2,42	deleterious	-3,16	deleterious	-2,91	medium_impact	3	damaging	0,49	damaging	0,05	deleterious	4,3	24	0,21	0,55	disease	0,62	disease	0,83	disease	0,57	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,85	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,67	0,72	0,9	1,75	6,75	N	0,28	N	0,73	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7108	7108	G	T	MI.4454	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1205	402	G	V	gGc/gTc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,34	deleterious	-6,2	deleterious	-4,49	high_impact	4,33	damaging	0,51	damaging	0,04	deleterious	3,88	23,5	0,15	0,55	disease	0,85	disease	0,9	disease	0,71	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	2,9	0,52	0,9	1,75	6,75	N	0,45	N	0,93	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7108	7108	G	A	MI.4455	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1205	402	G	D	gGc/gAc	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	2,42	deleterious	-3,2	deleterious	-3,4	high_impact	4,67	damaging	0,3	damaging	0,03	deleterious	3,96	23,6	0,17	0,55	disease	0,8	disease	0,9	disease	0,79	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,58	medium_impact	-0,92	high_impact	3,21	0,47	0,9	1,75	6,75	P	0,75	P	0,97	disease_causing	1	0,47	.	.	.	.	.	.	COSM1138402	.	.	.	.	.	.	.	.
chrM	7108	7108	G	C	MI.4456	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1205	402	G	A	gGc/gCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,38	deleterious	-3,99	deleterious	-3	high_impact	3,87	neutral	0,61	damaging	0,06	deleterious	3,23	22,8	0,22	0,55	disease	0,64	disease	0,74	disease	0,67	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,47	0,65	0,9	1,75	6,75	N	0,46	N	0,64	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7110	7110	T	C	MI.4457	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1207	403	Y	H	Tac/Cac	-15,84	0	0	probably_damaging	1	deleterious	0,02	neutral	2,78	neutral	-0,25	neutral	-1,22	medium_impact	2,29	neutral	0,64	damaging	0,1	deleterious	3,72	23,3	0,57	0,6	neutral	0,22	disease	0,54	neutral	0,2	neutral	0,48	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,71	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,02	0,23	0,9	7,21	13,45	N	0,36	N	0,79	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7110	7110	T	G	MI.4458	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1207	403	Y	D	Tac/Gac	-15,84	0	0	probably_damaging	1	deleterious	0,01	neutral	2,79	neutral	0,05	neutral	-1,92	medium_impact	2,29	neutral	0,62	damaging	0,11	deleterious	4,1	23,7	0,38	0,55	neutral	0,24	disease	0,77	neutral	0,4	disease	0,62	2	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,02	0,42	0,9	7,21	13,45	N	0,3	N	0,85	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7110	7110	T	A	MI.4459	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1207	403	Y	N	Tac/Aac	-15,84	0	0	probably_damaging	1	neutral	0,11	neutral	2,81	neutral	0,19	neutral	-1,54	low_impact	1,59	neutral	0,66	damaging	0,12	deleterious	4,17	23,8	0,41	0,55	neutral	0,24	disease	0,75	neutral	0,34	disease	0,56	1	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,73	low_impact	-3,58	medium_impact	-0,31	medium_impact	0,37	0,31	0,9	7,21	13,45	N	0,31	N	0,8	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8735	8735	T	C	MI.446	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	209	70	L	P	cTt/cCt	-1,26	0	0	probably_damaging	1	neutral	0,28	neutral	3,97	neutral	1,99	deleterious	-5,61	low_impact	1,1	neutral	0,74	neutral	0,44	deleterious	3,67	23,2	0,2	0,65	neutral	0,4	disease	0,81	disease	0,53	disease	0,54	1	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,06	medium_impact	-0,16	0,59	0,9	49,12	8,68	N	0,3	N	1	polymorphism	0,9	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7111	7111	A	C	MI.4460	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1208	403	Y	S	tAc/tCc	7,53	1	0	probably_damaging	1	deleterious	0,02	neutral	2,82	neutral	0,51	neutral	-1,11	low_impact	1,48	neutral	0,65	damaging	0,14	deleterious	3,81	23,4	0,29	0,55	neutral	0,17	disease	0,6	neutral	0,34	neutral	0,48	0	deleterious	1	neutral	0,01	deleterious	2	deleterious	0,71	low_impact	-3,58	medium_impact	-0,75	medium_impact	0,27	0,31	0,9	7,21	13,45	N	0,46	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7111	7111	A	G	MI.4461	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1208	403	Y	C	tAc/tGc	7,53	1	0	probably_damaging	1	deleterious	0,03	neutral	2,77	neutral	-2,77	neutral	-0,87	low_impact	1,48	neutral	0,64	damaging	0,1	deleterious	3,63	23,2	0,37	0,55	disease	0,66	disease	0,78	neutral	0,22	disease	0,62	2	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,78	low_impact	-3,58	medium_impact	-0,65	medium_impact	0,27	0,07	0,9	7,21	13,45	N	0,41	N	0,69	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7111	7111	A	T	MI.4462	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1208	403	Y	F	tAc/tTc	7,53	1	0	probably_damaging	1	neutral	0,37	neutral	2,82	neutral	0,19	neutral	0,16	neutral_impact	-0,33	neutral	0,71	neutral	0,85	deleterious	2,27	17,99	0,45	0,55	neutral	0,38	neutral	0,47	neutral	0,15	neutral	0,47	1	deleterious	1	neutral	0,19	neutral	-2	deleterious	0,72	low_impact	-3,58	medium_impact	0,06	low_impact	-1,4	0,34	0,9	7,21	13,45	P	0,58	P	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7113	7113	A	T	MI.4463	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1210	404	T	S	Acc/Tcc	-7,74	0	0	probably_damaging	0,99	neutral	0,58	neutral	2,85	neutral	0,07	neutral	-0,52	neutral_impact	0,16	neutral	0,68	neutral	0,86	neutral	-0,26	0,83	0,45	0,55	neutral	0,32	neutral	0,21	neutral	0,12	neutral	0,38	2	deleterious	0,99	neutral	0,3	neutral	-2	deleterious	0,67	low_impact	-2,64	medium_impact	0,27	medium_impact	-0,95	0,53	0,9	9,16	16,82	N	0,42	N	0,42	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7113	7113	A	C	MI.4464	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1210	404	T	P	Acc/Ccc	-7,74	0	0	probably_damaging	1	deleterious	0,02	neutral	2,8	neutral	-1,18	neutral	-1,81	medium_impact	3,02	damaging	0,59	neutral	0,4	deleterious	3,38	23	0,21	0,55	disease	0,57	disease	0,83	neutral	0,29	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,69	0,46	0,9	9,16	16,82	N	0,35	N	0,75	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7113	7113	A	G	MI.4465	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1210	404	T	A	Acc/Gcc	-7,74	0	0	probably_damaging	0,99	neutral	0,06	neutral	2,84	neutral	0,3	neutral	-1,06	medium_impact	2,16	neutral	0,68	neutral	0,68	neutral	1,55	13,6	0,67	0,7	neutral	0,3	neutral	0,45	neutral	0,31	neutral	0,46	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,68	low_impact	-2,64	medium_impact	-0,47	medium_impact	0,9	0,41	0,9	9,16	16,82	N	0,5	N	0,67	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7114	7114	C	A	MI.4466	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1211	404	T	N	aCc/aAc	3,14	0,97	0	probably_damaging	1	neutral	0,13	neutral	2,81	neutral	-0,3	neutral	-1,11	low_impact	1,07	neutral	0,65	neutral	0,67	deleterious	2,14	17,12	0,52	0,6	neutral	0,18	disease	0,69	neutral	0,18	neutral	0,47	1	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,69	low_impact	-3,58	medium_impact	-0,27	medium_impact	-0,11	0,69	0,9	9,16	16,82	P	0,52	P	0,71	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7114	7114	C	T	MI.4467	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1211	404	T	I	aCc/aTc	3,14	0,97	0	probably_damaging	1	deleterious	0,02	neutral	2,8	neutral	-1,46	neutral	-1,6	medium_impact	2,58	neutral	0,67	neutral	0,55	deleterious	2,5	19,45	0,44	0,55	neutral	0,33	disease	0,72	neutral	0,34	disease	0,52	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,72	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,28	0,57	0,9	9,16	16,82	N	0,43	N	0,57	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7114	7114	C	G	MI.4468	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1211	404	T	S	aCc/aGc	3,14	0,97	0	probably_damaging	0,99	neutral	0,58	neutral	2,85	neutral	0,07	neutral	-0,52	neutral_impact	0,16	neutral	0,68	neutral	0,86	deleterious	0,09	3,48	0,45	0,55	neutral	0,32	neutral	0,21	neutral	0,12	neutral	0,38	2	deleterious	0,99	neutral	0,3	neutral	-2	deleterious	0,67	low_impact	-2,64	medium_impact	0,27	medium_impact	-0,95	0,53	0,9	9,16	16,82	N	0,42	N	0,42	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7116	7116	C	G	MI.4469	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1213	405	L	V	Cta/Gta	-12,13	0	0	probably_damaging	0,99	deleterious	0	neutral	2,73	neutral	-2,04	neutral	-1,12	medium_impact	3,33	neutral	0,61	damaging	0,14	deleterious	3,56	23,1	0,39	0,55	neutral	0,23	disease	0,67	disease	0,56	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,69	low_impact	-2,64	low_impact	-1,48	medium_impact	1,98	0,48	0,9	8,58	10,68	N	0,34	N	0,66	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8737	8737	A	C	MI.447	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	211	71	M	L	Ata/Cta	-4,73	0	0	possibly_damaging	0,81	neutral	1	neutral	4,88	neutral	2,79	neutral	-1,2	neutral_impact	0,17	neutral	0,88	neutral	0,45	neutral	0,93	10,24	0,35	0,65	neutral	0,27	neutral	0,36	neutral	0,38	neutral	0,44	1	neutral	0,81	deleterious	0,6	neutral	-3	deleterious	0,51	low_impact	-1,35	high_impact	1,98	medium_impact	-0,95	0,46	0,9	44,25	8,42	N	0,27	N	0,93	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7116	7116	C	A	MI.4470	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1213	405	L	M	Cta/Ata	-12,13	0	0	probably_damaging	1	neutral	0,16	neutral	2,66	neutral	-1,85	neutral	-0,13	neutral_impact	0,4	neutral	0,63	neutral	0,43	deleterious	1,95	15,89	0,26	0,55	disease	0,59	neutral	0,13	neutral	0,17	neutral	0,33	3	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,7	low_impact	-3,58	medium_impact	-0,21	medium_impact	-0,73	0,7	0,9	8,58	10,68	N	0,53	P	0,59	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7117	7117	T	G	MI.4471	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1214	405	L	R	cTa/cGa	-0,1	0	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-4,26	neutral	-2,47	high_impact	4,37	neutral	0,63	damaging	0,1	deleterious	4,3	24	0,19	0,55	disease	0,77	disease	0,93	disease	0,72	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	2,94	0,65	0,9	8,58	10,68	N	0,4	N	0,9	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7117	7117	T	C	MI.4472	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1214	405	L	P	cTa/cCa	-0,1	0	0	probably_damaging	1	deleterious	0,02	neutral	2,66	deleterious	-4,54	deleterious	-2,98	medium_impact	3,48	damaging	0,59	damaging	0,11	deleterious	4,03	23,7	0,18	0,55	disease	0,83	disease	0,9	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,92	low_impact	-3,58	medium_impact	-0,75	high_impact	2,11	0,48	0,9	8,58	10,68	N	0,24	N	0,83	disease_causing	0,8	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7117	7117	T	A	MI.4473	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1214	405	L	Q	cTa/cAa	-0,1	0	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-4,59	neutral	-2,3	high_impact	4,37	neutral	0,68	damaging	0,12	deleterious	4,19	23,8	0,2	0,55	disease	0,79	disease	0,81	disease	0,58	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,94	0,54	0,9	8,58	10,68	N	0,38	N	0,82	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7119	7119	G	A	MI.4474	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1216	406	D	N	Gac/Aac	-6,81	0	0	benign	0	neutral	1	neutral	3,18	neutral	1,29	neutral	1,96	neutral_impact	-1,94	neutral	0,85	neutral	0,93	neutral	-0,35	0,51	0,77	0,8	neutral	0,18	neutral	0,1	neutral	0,11	neutral	0,27	5	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,07	high_impact	1,86	low_impact	-2,89	0,66	0,9	12,67	21,61	N	0,36	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7119	7119	G	T	MI.4475	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1216	406	D	Y	Gac/Tac	-6,81	0	0	possibly_damaging	0,78	deleterious	0	neutral	2,91	neutral	-1,52	neutral	-1	medium_impact	1,96	neutral	0,66	neutral	0,58	deleterious	3,97	23,6	0,27	0,55	disease	0,6	disease	0,71	disease	0,51	disease	0,54	1	deleterious	1	neutral	0,11	deleterious	4	deleterious	0,62	low_impact	-1,27	low_impact	-1,48	medium_impact	0,71	0,23	0,9	12,67	21,61	N	0,34	N	0,71	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7119	7119	G	C	MI.4476	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1216	406	D	H	Gac/Cac	-6,81	0	0	possibly_damaging	0,72	neutral	0,62	neutral	2,91	neutral	-1,54	neutral	0,68	neutral_impact	0,24	neutral	0,67	neutral	0,85	deleterious	1,89	15,53	0,43	0,55	neutral	0,31	neutral	0,28	neutral	0,24	neutral	0,4	2	neutral	0,67	neutral	0,45	neutral	-3	deleterious	0,45	low_impact	-1,14	medium_impact	0,31	medium_impact	-0,88	0,31	0,9	12,67	21,61	N	0,32	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7120	7120	A	C	MI.4477	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1217	406	D	A	gAc/gCc	-0,1	0	0	benign	0,11	deleterious	0	neutral	2,93	neutral	-0,98	neutral	-1,22	medium_impact	2,77	neutral	0,63	neutral	0,67	deleterious	2,09	16,82	0,38	0,55	neutral	0,28	neutral	0,43	neutral	0,47	neutral	0,45	1	deleterious	1	neutral	0,45	deleterious	1	neutral	0,19	medium_impact	0,1	low_impact	-1,48	medium_impact	1,46	0,35	0,9	12,67	21,61	N	0,49	N	0,44	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7120	7120	A	G	MI.4478	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1217	406	D	G	gAc/gGc	-0,1	0	0	benign	0,18	deleterious	0,01	neutral	2,95	neutral	-0,64	neutral	-0,55	low_impact	1,8	neutral	0,67	neutral	0,52	deleterious	2,31	18,26	0,34	0,55	neutral	0,43	disease	0,62	neutral	0,48	neutral	0,5	0	deleterious	0,99	neutral	0,42	neutral	-2	neutral	0,24	medium_impact	-0,14	medium_impact	-0,92	medium_impact	0,56	0,29	0,9	12,67	21,61	N	0,41	N	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7120	7120	A	T	MI.4479	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1217	406	D	V	gAc/gTc	-0,1	0	0	possibly_damaging	0,46	deleterious	0	neutral	2,89	neutral	-2,81	neutral	-1,8	medium_impact	2,77	neutral	0,65	neutral	0,64	deleterious	3,63	23,2	0,28	0,55	neutral	0,46	disease	0,67	neutral	0,45	neutral	0,5	0	deleterious	1	neutral	0,27	deleterious	4	deleterious	0,46	medium_impact	-0,69	low_impact	-1,48	medium_impact	1,46	0,16	0,9	12,67	21,61	N	0,41	N	0,77	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8737	8737	A	T	MI.448	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	211	71	M	L	Ata/Tta	-4,73	0	0	possibly_damaging	0,81	neutral	1	neutral	4,88	neutral	2,79	neutral	-1,2	neutral_impact	0,17	neutral	0,88	neutral	0,45	neutral	1,03	10,84	0,35	0,65	neutral	0,27	neutral	0,36	neutral	0,38	neutral	0,44	1	neutral	0,81	deleterious	0,6	neutral	-3	deleterious	0,51	low_impact	-1,35	high_impact	1,98	medium_impact	-0,95	0,46	0,9	44,25	8,42	N	0,27	N	0,93	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7121	7121	C	G	MI.4480	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1218	406	D	E	gaC/gaG	5,91	0,67	0	benign	0,18	deleterious	0	neutral	2,93	neutral	-1,07	neutral	-0,28	medium_impact	2,42	neutral	0,63	neutral	0,57	deleterious	2,29	18,11	0,58	0,65	neutral	0,22	disease	0,52	neutral	0,39	disease	0,5	0	deleterious	1	neutral	0,41	deleterious	1	neutral	0,19	medium_impact	-0,14	low_impact	-1,48	medium_impact	1,14	0,62	0,9	12,67	21,61	N	0,49	N	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7121	7121	C	A	MI.4481	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1218	406	D	E	gaC/gaA	5,91	0,67	0	benign	0,18	deleterious	0	neutral	2,93	neutral	-1,07	neutral	-0,28	medium_impact	2,42	neutral	0,63	neutral	0,57	deleterious	2,59	20,2	0,58	0,65	neutral	0,22	disease	0,52	neutral	0,39	disease	0,5	0	deleterious	1	neutral	0,41	deleterious	1	neutral	0,19	medium_impact	-0,14	low_impact	-1,48	medium_impact	1,14	0,62	0,9	12,67	21,61	N	0,49	N	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7122	7122	C	G	MI.4482	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1219	407	Q	E	Caa/Gaa	-1,95	0	0	benign	0	neutral	0,82	neutral	2,99	neutral	1,24	neutral	0,09	neutral_impact	-1,22	neutral	0,74	neutral	0,85	neutral	-0,42	0,35	0,61	0,65	neutral	0,32	neutral	0,22	neutral	0,13	neutral	0,4	2	neutral	0,17	deleterious	0,91	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,56	low_impact	-2,23	0,59	0,9	14,42	24,47	N	0,4	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7122	7122	C	A	MI.4483	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1219	407	Q	K	Caa/Aaa	-1,95	0	0	benign	0,09	neutral	1	neutral	2,8	neutral	-0,13	neutral	-0,13	neutral_impact	-0,34	neutral	0,71	neutral	0,38	neutral	1,08	11,1	0,57	0,6	neutral	0,18	neutral	0,49	neutral	0,17	neutral	0,41	2	neutral	0,09	deleterious	0,96	neutral	-6	neutral	0,17	medium_impact	0,19	high_impact	1,86	low_impact	-1,41	0,43	0,9	14,42	24,47	N	0,3	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7123	7123	A	C	MI.4484	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1220	407	Q	P	cAa/cCa	-3,57	0	0	benign	0,24	neutral	0,9	neutral	2,76	neutral	-0,58	neutral	0,31	neutral_impact	-1,3	neutral	0,72	neutral	0,95	neutral	-0,92	0,02	0,25	0,55	neutral	0,16	disease	0,52	neutral	0,31	neutral	0,4	2	neutral	0,13	deleterious	0,83	neutral	-6	neutral	0,28	medium_impact	-0,29	medium_impact	0,72	low_impact	-2,3	0,35	0,9	14,42	24,47	N	0,26	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7123	7123	A	T	MI.4485	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1220	407	Q	L	cAa/cTa	-3,57	0	0	benign	0,09	neutral	0,1	neutral	2,7	neutral	-2,04	neutral	-1,35	low_impact	1,26	neutral	0,72	neutral	0,41	deleterious	2,16	17,27	0,39	0,55	neutral	0,38	disease	0,64	neutral	0,28	neutral	0,46	1	neutral	0,89	deleterious	0,51	neutral	-6	neutral	0,2	medium_impact	0,19	medium_impact	-0,34	medium_impact	0,06	0,15	0,9	14,42	24,47	N	0,45	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7123	7123	A	G	MI.4486	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1220	407	Q	R	cAa/cGa	-3,57	0	0	benign	0,09	neutral	0,42	neutral	2,75	neutral	-0,69	neutral	-0,51	neutral_impact	0,76	neutral	0,65	damaging	0,2	neutral	1,71	14,48	0,53	0,6	neutral	0,2	disease	0,64	neutral	0,22	neutral	0,49	0	neutral	0,52	deleterious	0,67	neutral	-6	neutral	0,19	medium_impact	0,19	medium_impact	0,12	medium_impact	-0,4	0,35	0,9	14,42	24,47	N	0,34	N	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7124	7124	A	C	MI.4487	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1221	407	Q	H	caA/caC	-0,8	0	0	benign	0	neutral	0,2	neutral	2,68	neutral	-2,49	neutral	-0,54	low_impact	1,26	neutral	0,71	neutral	0,48	deleterious	2,11	16,92	0,55	0,6	neutral	0,41	neutral	0,42	neutral	0,2	neutral	0,49	0	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,16	high_impact	2,07	medium_impact	-0,14	medium_impact	0,06	0,56	0,9	14,42	24,47	N	0,51	P	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7124	7124	A	T	MI.4488	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1221	407	Q	H	caA/caT	-0,8	0	0	benign	0	neutral	0,2	neutral	2,68	neutral	-2,49	neutral	-0,54	low_impact	1,26	neutral	0,71	neutral	0,48	deleterious	2,33	18,39	0,55	0,6	neutral	0,41	neutral	0,42	neutral	0,2	neutral	0,49	0	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,16	high_impact	2,07	medium_impact	-0,14	medium_impact	0,06	0,56	0,9	14,42	24,47	N	0,51	P	0,26	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7125	7125	A	G	MI.4489	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1222	408	T	A	Acc/Gcc	-5,89	0	0	benign	0	neutral	0,2	neutral	2,96	neutral	-0,61	neutral	-0,42	low_impact	1,75	neutral	0,7	neutral	0,9	neutral	-0,65	0,1	0,53	0,6	neutral	0,3	neutral	0,36	neutral	0,22	neutral	0,45	1	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,13	high_impact	2,07	medium_impact	-0,14	medium_impact	0,52	0,32	0,9	11,7	29,21	P	0,53	P	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8737	8737	A	G	MI.449	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	211	71	M	V	Ata/Gta	-4,73	0	0	possibly_damaging	0,87	neutral	0,18	neutral	4,44	neutral	0,54	neutral	-2,11	low_impact	1,72	neutral	0,84	damaging	0,18	deleterious	2,52	19,59	0,42	0,65	neutral	0,37	disease	0,67	neutral	0,49	neutral	0,48	0	neutral	0,93	neutral	0,16	neutral	-3	deleterious	0,62	low_impact	-1,54	medium_impact	-0,08	medium_impact	0,38	0,58	0,9	44,25	8,42	N	0,28	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7125	7125	A	T	MI.4490	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1222	408	T	S	Acc/Tcc	-5,89	0	0	benign	0,03	neutral	0,41	neutral	2,97	neutral	-0,47	neutral	-0,1	neutral_impact	0,62	neutral	0,67	neutral	0,71	neutral	-0,69	0,08	0,54	0,6	neutral	0,3	neutral	0,39	neutral	0,22	neutral	0,45	1	neutral	0,56	deleterious	0,69	neutral	-6	neutral	0,16	medium_impact	0,66	medium_impact	0,11	medium_impact	-0,53	0,67	0,9	11,7	29,21	N	0,45	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7125	7125	A	C	MI.4491	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1222	408	T	P	Acc/Ccc	-5,89	0	0	benign	0,32	neutral	0,07	neutral	2,92	neutral	-1,83	neutral	-0,8	low_impact	1,84	damaging	0,59	neutral	0,37	deleterious	0,37	6,36	0,19	0,55	disease	0,58	disease	0,83	neutral	0,38	disease	0,72	4	neutral	0,92	neutral	0,38	neutral	-6	deleterious	0,45	medium_impact	-0,45	medium_impact	-0,43	medium_impact	0,6	0,57	0,9	11,7	29,21	N	0,36	N	0,79	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7126	7126	C	T	MI.4492	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1223	408	T	I	aCc/aTc	1,29	0,01	0	benign	0,01	neutral	0,31	neutral	2,96	neutral	-0,65	neutral	-0,79	low_impact	1,4	neutral	0,67	neutral	0,76	deleterious	0,44	6,94	0,48	0,55	disease	0,55	disease	0,58	neutral	0,14	neutral	0,45	1	neutral	0,68	deleterious	0,65	neutral	-6	neutral	0,2	medium_impact	1,12	medium_impact	0	medium_impact	0,19	0,5	0,9	11,7	29,21	N	0,54	P	0,55	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7126	7126	C	G	MI.4493	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1223	408	T	S	aCc/aGc	1,29	0,01	0	benign	0,03	neutral	0,41	neutral	2,97	neutral	-0,47	neutral	-0,1	neutral_impact	0,62	neutral	0,67	neutral	0,71	neutral	-0,36	0,48	0,54	0,6	neutral	0,3	neutral	0,39	neutral	0,22	neutral	0,45	1	neutral	0,56	deleterious	0,69	neutral	-6	neutral	0,16	medium_impact	0,66	medium_impact	0,11	medium_impact	-0,53	0,67	0,9	11,7	29,21	N	0,49	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7126	7126	C	A	MI.4494	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1223	408	T	N	aCc/aAc	1,29	0,01	0	benign	0,32	neutral	0,13	neutral	2,93	neutral	-1,39	neutral	-0,21	neutral_impact	0,18	neutral	0,66	neutral	0,67	deleterious	0,56	7,89	0,62	0,65	neutral	0,29	disease	0,64	neutral	0,14	neutral	0,43	1	neutral	0,85	neutral	0,41	neutral	-6	neutral	0,4	medium_impact	-0,45	medium_impact	-0,27	medium_impact	-0,93	0,7	0,9	11,7	29,21	N	0,58	P	0,71	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7128	7128	T	G	MI.4495	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1225	409	Y	D	Tac/Gac	-3,57	0	0	possibly_damaging	0,73	deleterious	0	neutral	2,78	neutral	-2,07	neutral	-2,21	low_impact	1,94	damaging	0,52	neutral	0,39	deleterious	2,45	19,15	0,31	0,55	disease	0,51	disease	0,78	disease	0,64	disease	0,78	6	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,71	low_impact	-1,16	low_impact	-1,48	medium_impact	0,69	0,54	0,9	14,62	66,11	N	0,31	N	0,72	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7128	7128	T	A	MI.4496	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1225	409	Y	N	Tac/Aac	-3,57	0	0	possibly_damaging	0,72	deleterious	0,02	neutral	2,78	neutral	-1,18	neutral	-2	low_impact	1,38	damaging	0,58	neutral	0,56	deleterious	2,45	19,14	0,38	0,55	neutral	0,39	disease	0,74	disease	0,52	disease	0,62	2	deleterious	0,98	neutral	0,15	deleterious	1	deleterious	0,63	low_impact	-1,14	medium_impact	-0,75	medium_impact	0,18	0,38	0,9	14,62	66,11	N	0,34	N	0,63	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7128	7128	T	C	MI.4497	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1225	409	Y	H	Tac/Cac	-3,57	0	0	possibly_damaging	0,79	deleterious	0,01	neutral	2,78	neutral	-1,44	neutral	-1,43	neutral_impact	0,5	neutral	0,64	neutral	0,41	neutral	1,72	14,53	0,49	0,55	neutral	0,28	disease	0,51	neutral	0,4	neutral	0,49	0	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,65	low_impact	-1,3	medium_impact	-0,92	medium_impact	-0,64	0,51	0,9	14,62	66,11	N	0,37	N	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7129	7129	A	C	MI.4498	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1226	409	Y	S	tAc/tCc	5,91	1	0	benign	0,2	deleterious	0,02	neutral	2,82	neutral	0,5	neutral	-1,51	neutral_impact	0,62	neutral	0,61	neutral	0,62	deleterious	2,05	16,5	0,28	0,55	neutral	0,24	disease	0,58	disease	0,53	disease	0,56	1	neutral	0,98	neutral	0,41	neutral	-2	neutral	0,37	medium_impact	-0,19	medium_impact	-0,75	medium_impact	-0,53	0,5	0,9	14,62	66,11	P	0,52	P	0,64	disease_causing	0,96	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7129	7129	A	G	MI.4499	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1226	409	Y	C	tAc/tGc	5,91	1	0	benign	0,01	deleterious	0	neutral	2,78	neutral	-1,27	neutral	-1,29	low_impact	1,94	neutral	0,63	neutral	0,74	neutral	1,74	14,63	0,34	0,55	neutral	0,42	disease	0,8	disease	0,55	disease	0,78	6	deleterious	1	deleterious	0,5	neutral	-2	neutral	0,21	medium_impact	1,12	low_impact	-1,48	medium_impact	0,69	0,18	0,9	14,62	66,11	P	0,53	P	0,05	disease_causing	0,97	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8545	8545	G	T	MI.45	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	19	7	A	S	Gct/Tct	-1,03	0	0,01	benign	0,06	neutral	1	neutral	4,78	neutral	0,02	neutral	0,22	neutral_impact	0,11	neutral	0,91	neutral	0,9	deleterious	0,49	7,33	0,45	0,65	neutral	0,32	neutral	0,22	neutral	0,28	neutral	0,35	3	neutral	0,06	deleterious	0,97	neutral	-6	neutral	0,18	medium_impact	0,38	high_impact	1,98	low_impact	-1	0,71	0,9	9,29	10,06	N	0,29	N	0,53	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8738	8738	T	A	MI.450	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	212	71	M	K	aTa/aAa	0,82	0,22	0	probably_damaging	0,94	deleterious	0,03	neutral	4,31	neutral	-2,26	deleterious	-4,72	medium_impact	2,37	neutral	0,79	damaging	0,08	deleterious	3,74	23,3	0,21	0,65	disease	0,69	disease	0,87	disease	0,72	disease	0,8	6	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,83	low_impact	-1,89	medium_impact	-0,56	medium_impact	0,93	0,46	0,9	44,25	8,42	N	0,22	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7129	7129	A	T	MI.4500	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1226	409	Y	F	tAc/tTc	5,91	1	0	benign	0,13	neutral	0,07	neutral	2,84	neutral	0,95	neutral	-0,13	neutral_impact	-0,11	neutral	0,67	neutral	0,8	deleterious	0,78	9,33	0,42	0,55	neutral	0,17	disease	0,52	neutral	0,29	neutral	0,42	2	neutral	0,92	deleterious	0,47	neutral	-6	neutral	0,24	medium_impact	0,02	medium_impact	-0,43	low_impact	-1,2	0,4	0,9	14,62	66,11	P	0,56	P	0,15	disease_causing	0,64	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7131	7131	G	C	MI.4501	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1228	410	A	P	Gcc/Ccc	1,75	1	0	probably_damaging	0,98	neutral	0,17	neutral	2,57	deleterious	-3,58	neutral	-1,12	medium_impact	2,53	damaging	0,58	neutral	0,35	deleterious	2,88	21,8	0,12	0,55	disease	0,66	disease	0,89	disease	0,54	disease	0,8	6	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,89	low_impact	-2,35	medium_impact	-0,19	medium_impact	1,24	0,86	0,9	9,16	16,63	N	0,42	N	0,66	polymorphism	0,87	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7131	7131	G	T	MI.4502	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1228	410	A	S	Gcc/Tcc	1,75	1	0	possibly_damaging	0,5	neutral	0,66	neutral	2,66	neutral	-1,4	neutral	-0,31	neutral_impact	0,12	neutral	0,69	neutral	0,53	deleterious	1,92	15,74	0,38	0,55	neutral	0,39	neutral	0,47	neutral	0,23	neutral	0,47	1	neutral	0,42	deleterious	0,58	neutral	-3	neutral	0,34	medium_impact	-0,76	medium_impact	0,35	medium_impact	-0,99	0,86	0,9	9,16	16,63	N	0,4	N	0,31	polymorphism	0,98	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7131	7131	G	A	MI.4503	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1228	410	A	T	Gcc/Acc	1,75	1	0	benign	0,04	neutral	0,8	neutral	2,61	neutral	-1,76	neutral	0,04	low_impact	1,03	neutral	0,72	neutral	0,91	deleterious	0,76	9,19	0,4	0,55	neutral	0,35	neutral	0,45	neutral	0,28	neutral	0,47	1	neutral	0,13	deleterious	0,88	neutral	-6	neutral	0,19	medium_impact	0,54	medium_impact	0,53	medium_impact	-0,15	0,77	0,9	9,16	16,63	N	0,41	N	0,36	polymorphism	0,96	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7132	7132	C	A	MI.4504	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1229	410	A	D	gCc/gAc	0,36	0,99	0	probably_damaging	0,97	neutral	0,07	neutral	2,59	neutral	-2,52	neutral	-1,46	medium_impact	2,88	neutral	0,64	neutral	0,36	deleterious	4,6	24,4	0,14	0,55	disease	0,64	disease	0,86	disease	0,55	disease	0,8	6	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,84	low_impact	-2,18	medium_impact	-0,43	medium_impact	1,56	0,64	0,9	9,16	16,63	N	0,38	N	0,93	disease_causing	0,68	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7132	7132	C	G	MI.4505	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1229	410	A	G	gCc/gGc	0,36	0,99	0	benign	0,27	neutral	0,43	neutral	2,78	neutral	0,7	neutral	-1,32	neutral_impact	0,5	neutral	0,7	neutral	0,57	neutral	1,05	10,94	0,28	0,55	neutral	0,19	neutral	0,42	neutral	0,25	neutral	0,44	1	neutral	0,48	deleterious	0,58	neutral	-6	neutral	0,27	medium_impact	-0,35	medium_impact	0,13	medium_impact	-0,64	0,79	0,9	9,16	16,63	N	0,42	N	0,53	polymorphism	0,72	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7132	7132	C	T	MI.4506	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1229	410	A	V	gCc/gTc	0,36	0,99	0	benign	0,38	neutral	0,12	neutral	2,66	neutral	-1,91	neutral	0,27	low_impact	1,9	neutral	0,69	neutral	0,54	deleterious	2,9	21,9	0,3	0,55	neutral	0,17	disease	0,72	neutral	0,39	disease	0,5	0	neutral	0,86	neutral	0,37	neutral	-6	deleterious	0,53	medium_impact	-0,56	medium_impact	-0,29	medium_impact	0,66	0,81	0,9	9,16	16,63	N	0,48	N	0,53	polymorphism	0,67	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7134	7134	A	C	MI.4507	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1231	411	K	Q	Aaa/Caa	-6,35	0	0	probably_damaging	1	neutral	0,09	neutral	2,63	neutral	-2,02	neutral	-1,77	medium_impact	3,15	damaging	0,53	neutral	0,43	deleterious	3,48	23,1	0,39	0,55	neutral	0,38	disease	0,76	neutral	0,41	disease	0,52	0	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,77	low_impact	-3,58	medium_impact	-0,37	medium_impact	1,81	0,76	0,9	2,53	6,64	N	0,44	N	0,64	polymorphism	0,66	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7134	7134	A	G	MI.4508	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1231	411	K	E	Aaa/Gaa	-6,35	0	0	probably_damaging	1	deleterious	0	neutral	2,63	neutral	-1,99	neutral	-1,8	high_impact	4,04	damaging	0,52	neutral	0,38	deleterious	4,11	23,7	0,28	0,55	neutral	0,38	disease	0,91	disease	0,64	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,63	0,73	0,9	2,53	6,64	N	0,42	N	0,75	polymorphism	0,53	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7135	7135	A	C	MI.4509	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1232	411	K	T	aAa/aCa	6,84	1	0	probably_damaging	1	deleterious	0,01	neutral	2,61	neutral	-2,43	deleterious	-2,68	high_impact	3,95	damaging	0,57	neutral	0,38	deleterious	3,69	23,3	0,2	0,55	neutral	0,45	disease	0,87	disease	0,61	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,58	medium_impact	-0,92	high_impact	2,55	0,54	0,9	2,53	6,64	P	0,49	N	0,76	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8738	8738	T	C	MI.451	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	212	71	M	T	aTa/aCa	0,82	0,22	0	probably_damaging	0,94	neutral	0,06	neutral	4,34	neutral	-0,93	deleterious	-4,19	medium_impact	2,12	neutral	0,88	damaging	0,17	deleterious	2,74	21,1	0,34	0,65	disease	0,5	disease	0,64	disease	0,52	neutral	0,47	1	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,74	low_impact	-1,89	medium_impact	-0,38	medium_impact	0,72	0,39	0,9	44,25	8,42	N	0,32	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7135	7135	A	T	MI.4510	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1232	411	K	M	aAa/aTa	6,84	1	0	probably_damaging	1	neutral	0,05	neutral	2,6	deleterious	-3,69	deleterious	-2,7	high_impact	3,95	neutral	0,61	neutral	0,46	deleterious	4,09	23,7	0,21	0,55	neutral	0,29	disease	0,86	disease	0,62	disease	0,68	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,74	low_impact	-3,58	medium_impact	-0,52	high_impact	2,55	0,61	0,9	2,53	6,64	P	0,53	P	0,89	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7136	7136	A	T	MI.4511	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1233	411	K	N	aaA/aaT	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,66	neutral	-2,43	neutral	-2,17	medium_impact	2,85	damaging	0,5	neutral	0,31	deleterious	3,99	23,6	0,44	0,55	neutral	0,4	disease	0,85	disease	0,55	disease	0,53	1	deleterious	1	neutral	0	deleterious	5	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	medium_impact	1,53	0,75	0,9	2,53	6,64	P	0,49	N	0,76	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7136	7136	A	C	MI.4512	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1233	411	K	N	aaA/aaC	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,66	neutral	-2,43	neutral	-2,17	medium_impact	2,85	damaging	0,5	neutral	0,31	deleterious	3,94	23,5	0,44	0,55	neutral	0,4	disease	0,85	disease	0,55	disease	0,53	1	deleterious	1	neutral	0	deleterious	5	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	medium_impact	1,53	0,75	0,9	2,53	6,64	P	0,49	N	0,76	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7137	7137	A	G	MI.4513	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1234	412	I	V	Atc/Gtc	3,37	0,99	0	benign	0	neutral	0,49	neutral	2,77	neutral	-0,32	neutral	-0,2	low_impact	1,34	neutral	0,7	neutral	0,94	neutral	-0,23	0,93	0,61	0,65	neutral	0,28	neutral	0,42	neutral	0,33	neutral	0,45	1	neutral	0,51	deleterious	0,75	neutral	-6	neutral	0,13	high_impact	2,07	medium_impact	0,18	medium_impact	0,14	0,59	0,9	13,06	40,88	P	0,56	P	0,04	polymorphism	0,98	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7137	7137	A	C	MI.4514	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1234	412	I	L	Atc/Ctc	3,37	0,99	0	benign	0,02	neutral	0,14	neutral	2,89	neutral	0,53	neutral	-0,48	low_impact	1,82	neutral	0,69	neutral	0,56	deleterious	0,73	9,03	0,38	0,55	neutral	0,26	disease	0,69	neutral	0,32	disease	0,5	0	neutral	0,85	deleterious	0,56	neutral	-6	neutral	0,16	medium_impact	0,83	medium_impact	-0,25	medium_impact	0,58	0,78	0,9	13,06	40,88	P	0,54	P	0,35	polymorphism	0,96	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7137	7137	A	T	MI.4515	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1234	412	I	F	Atc/Ttc	3,37	0,99	0	benign	0,28	deleterious	0,03	neutral	2,69	neutral	-1,31	neutral	-1,36	medium_impact	3,02	neutral	0,62	neutral	0,35	deleterious	1,89	15,55	0,32	0,55	disease	0,54	disease	0,86	neutral	0,5	disease	0,67	3	neutral	0,97	neutral	0,38	deleterious	1	neutral	0,42	medium_impact	-0,37	medium_impact	-0,65	medium_impact	1,69	0,79	0,9	13,06	40,88	N	0,42	N	0,59	disease_causing	0,78	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7138	7138	T	C	MI.4516	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1235	412	I	T	aTc/aCc	0,36	0,12	0	benign	0,08	neutral	0,08	neutral	2,68	neutral	-1,57	neutral	-1,24	low_impact	1,73	neutral	0,71	neutral	0,97	deleterious	0,4	6,59	0,29	0,55	neutral	0,48	disease	0,69	neutral	0,37	disease	0,51	0	neutral	0,91	deleterious	0,5	neutral	-6	neutral	0,24	medium_impact	0,24	medium_impact	-0,4	medium_impact	0,5	0,83	0,9	13,06	40,88	N	0,47	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7138	7138	T	G	MI.4517	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1235	412	I	S	aTc/aGc	0,36	0,12	0	possibly_damaging	0,64	neutral	0,27	neutral	2,66	neutral	-1,85	neutral	-1,48	low_impact	1,93	neutral	0,69	neutral	0,72	neutral	1,67	14,26	0,19	0,55	disease	0,51	disease	0,82	neutral	0,39	disease	0,53	1	neutral	0,76	neutral	0,32	neutral	-3	deleterious	0,43	medium_impact	-0,99	medium_impact	-0,05	medium_impact	0,68	0,68	0,9	13,06	40,88	N	0,38	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7138	7138	T	A	MI.4518	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1235	412	I	N	aTc/aAc	0,36	0,12	0	possibly_damaging	0,83	deleterious	0,01	neutral	2,62	deleterious	-3,57	neutral	-2,2	high_impact	3,5	neutral	0,69	neutral	0,45	deleterious	4,44	24,2	0,17	0,55	disease	0,71	disease	0,89	disease	0,58	disease	0,68	4	deleterious	0,99	neutral	0,09	deleterious	5	deleterious	0,76	low_impact	-1,4	medium_impact	-0,92	high_impact	2,13	0,72	0,9	13,06	40,88	N	0,36	N	0,61	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7139	7139	C	A	MI.4519	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1236	412	I	M	atC/atA	1,05	0,1	0	possibly_damaging	0,54	neutral	0,07	neutral	2,67	neutral	-1,68	neutral	-0,74	medium_impact	2,03	neutral	0,69	neutral	0,59	neutral	1,19	11,7	0,39	0,55	neutral	0,42	disease	0,63	neutral	0,35	neutral	0,48	0	neutral	0,93	neutral	0,27	NA	0	neutral	0,29	medium_impact	-0,82	medium_impact	-0,43	medium_impact	0,78	0,82	0,9	13,06	40,88	N	0,51	P	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8739	8739	A	T	MI.452	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	213	71	M	I	atA/atT	5,68	0,91	0	probably_damaging	0,91	neutral	0,53	neutral	4,5	neutral	1,13	neutral	-1,79	neutral_impact	-0,08	neutral	0,8	neutral	0,41	neutral	1,71	14,47	0,35	0,65	neutral	0,3	neutral	0,36	neutral	0,42	neutral	0,44	1	neutral	0,9	neutral	0,31	neutral	-2	deleterious	0,63	low_impact	-1,71	medium_impact	0,32	low_impact	-1,17	0,59	0,9	44,25	8,42	N	0,4	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7139	7139	C	G	MI.4520	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1236	412	I	M	atC/atG	1,05	0,1	0	possibly_damaging	0,54	neutral	0,07	neutral	2,67	neutral	-1,68	neutral	-0,74	medium_impact	2,03	neutral	0,69	neutral	0,59	deleterious	0,75	9,17	0,39	0,55	neutral	0,42	disease	0,63	neutral	0,35	neutral	0,48	0	neutral	0,93	neutral	0,27	NA	0	neutral	0,29	medium_impact	-0,82	medium_impact	-0,43	medium_impact	0,78	0,82	0,9	13,06	40,88	N	0,5	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7140	7140	C	A	MI.4521	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1237	413	H	N	Cat/Aat	-4,04	0	0	benign	0,36	deleterious	0	neutral	2,74	neutral	-2,95	neutral	-1,08	medium_impact	3,24	neutral	0,66	neutral	0,39	deleterious	2,45	19,13	0,44	0,55	neutral	0,45	disease	0,9	disease	0,69	disease	0,77	5	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,49	medium_impact	-0,52	low_impact	-1,48	medium_impact	1,89	0,72	0,9	10,53	13,67	N	0,36	N	0,56	polymorphism	0,94	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7140	7140	C	G	MI.4522	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1237	413	H	D	Cat/Gat	-4,04	0	0	possibly_damaging	0,82	deleterious	0	neutral	2,73	deleterious	-3,06	neutral	-1,38	high_impact	4,21	neutral	0,63	neutral	0,32	deleterious	3,91	23,5	0,22	0,55	neutral	0,47	disease	0,92	disease	0,78	disease	0,81	6	deleterious	1	neutral	0,09	deleterious	5	deleterious	0,62	low_impact	-1,38	low_impact	-1,48	high_impact	2,79	0,74	0,9	10,53	13,67	N	0,48	N	0,78	polymorphism	0,83	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7140	7140	C	T	MI.4523	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1237	413	H	Y	Cat/Tat	-4,04	0	0	possibly_damaging	0,63	deleterious	0	neutral	2,72	deleterious	-3,4	neutral	-1,26	high_impact	3,66	neutral	0,64	neutral	0,29	deleterious	3,6	23,2	0,43	0,55	disease	0,62	disease	0,91	disease	0,7	disease	0,78	6	deleterious	1	neutral	0,19	deleterious	5	deleterious	0,76	medium_impact	-0,97	low_impact	-1,48	high_impact	2,28	0,61	0,9	10,53	13,67	N	0,32	N	0,78	polymorphism	0,93	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7141	7141	A	C	MI.4524	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1238	413	H	P	cAt/cCt	4,52	1	0	possibly_damaging	0,81	deleterious	0,01	neutral	2,72	deleterious	-3,5	neutral	-1,88	high_impact	3,66	neutral	0,62	neutral	0,29	deleterious	3,21	22,7	0,21	0,55	disease	0,62	disease	0,96	disease	0,78	disease	0,9	8	deleterious	0,99	neutral	0,1	deleterious	5	deleterious	0,77	low_impact	-1,35	medium_impact	-0,92	high_impact	2,28	0,6	0,9	10,53	13,67	P	0,51	P	0,83	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7141	7141	A	T	MI.4525	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1238	413	H	L	cAt/cTt	4,52	1	0	possibly_damaging	0,74	neutral	0,07	neutral	2,77	neutral	-2,14	neutral	-2,37	high_impact	4,21	neutral	0,68	neutral	0,38	deleterious	4,01	23,6	0,23	0,55	neutral	0,34	disease	0,94	disease	0,7	disease	0,84	7	neutral	0,95	neutral	0,17	deleterious	1	deleterious	0,74	low_impact	-1,18	medium_impact	-0,43	high_impact	2,79	0,48	0,9	10,53	13,67	P	0,6	P	0,73	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7141	7141	A	G	MI.4526	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1238	413	H	R	cAt/cGt	4,52	1	0	possibly_damaging	0,67	deleterious	0	neutral	2,73	deleterious	-3,01	neutral	-0,89	high_impact	3,52	neutral	0,63	neutral	0,28	deleterious	2,92	21,9	0,51	0,6	neutral	0,43	disease	0,94	disease	0,74	disease	0,88	8	deleterious	1	neutral	0,17	deleterious	5	deleterious	0,77	low_impact	-1,05	low_impact	-1,48	high_impact	2,15	0,63	0,9	10,53	13,67	N	0,49	N	0,68	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7142	7142	T	G	MI.4527	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1239	413	H	Q	caT/caG	8,69	1	0	benign	0,15	neutral	0,49	neutral	2,9	neutral	-0,6	neutral	0,47	neutral_impact	-0,26	neutral	0,77	neutral	0,92	neutral	-0,9	0,03	0,54	0,6	neutral	0,33	neutral	0,2	neutral	0,46	neutral	0,34	3	neutral	0,42	deleterious	0,67	neutral	-6	neutral	0,2	medium_impact	-0,05	medium_impact	0,18	low_impact	-1,34	0,81	0,9	10,53	13,67	P	0,57	P	0,06	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7142	7142	T	A	MI.4528	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1239	413	H	Q	caT/caA	8,69	1	0	benign	0,15	neutral	0,49	neutral	2,9	neutral	-0,6	neutral	0,47	neutral_impact	-0,26	neutral	0,77	neutral	0,92	neutral	-0,81	0,04	0,54	0,6	neutral	0,33	neutral	0,2	neutral	0,46	neutral	0,34	3	neutral	0,42	deleterious	0,67	neutral	-6	neutral	0,2	medium_impact	-0,05	medium_impact	0,18	low_impact	-1,34	0,81	0,9	10,53	13,67	P	0,58	P	0,06	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7143	7143	T	G	MI.4529	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1240	414	F	V	Ttc/Gtc	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	2,34	neutral	-2,59	deleterious	-3,44	high_impact	4,37	neutral	0,69	damaging	0,04	deleterious	4,3	24	0,19	0,55	disease	0,65	disease	0,92	disease	0,61	disease	0,72	4	deleterious	1	deleterious	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,94	0,75	0,9	2,14	6,8	N	0,37	N	0,84	polymorphism	0,62	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8739	8739	A	C	MI.453	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	213	71	M	I	atA/atC	5,68	0,91	0	probably_damaging	0,91	neutral	0,53	neutral	4,5	neutral	1,13	neutral	-1,79	neutral_impact	-0,08	neutral	0,8	neutral	0,41	neutral	1,66	14,21	0,35	0,65	neutral	0,3	neutral	0,36	neutral	0,42	neutral	0,44	1	neutral	0,9	neutral	0,31	neutral	-2	deleterious	0,63	low_impact	-1,71	medium_impact	0,32	low_impact	-1,17	0,59	0,9	44,25	8,42	N	0,39	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7143	7143	T	C	MI.4530	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1240	414	F	L	Ttc/Ctc	-3,34	0	0	probably_damaging	0,99	deleterious	0	neutral	2,38	neutral	-2,16	deleterious	-2,95	high_impact	4,02	neutral	0,72	damaging	0,04	deleterious	4,31	24	0,38	0,55	neutral	0,48	disease	0,87	disease	0,6	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,64	low_impact	-1,48	high_impact	2,61	0,8	0,9	2,14	6,8	N	0,25	N	0,83	polymorphism	0,76	0,27	rs879117005	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7143	7143	T	A	MI.4531	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1240	414	F	I	Ttc/Atc	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	2,37	neutral	-2,25	deleterious	-2,95	high_impact	4,02	neutral	0,71	damaging	0,05	deleterious	4,71	24,6	0,18	0,55	disease	0,68	disease	0,9	disease	0,66	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,61	0,73	0,9	2,14	6,8	N	0,31	N	0,88	polymorphism	0,77	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7144	7144	T	G	MI.4532	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1241	414	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	neutral	0,06	neutral	2,25	deleterious	-4,73	deleterious	-3,94	high_impact	4,16	neutral	0,73	damaging	0,04	deleterious	4,23	23,9	0,15	0,55	disease	0,89	disease	0,91	disease	0,69	disease	0,8	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,87	low_impact	-3,58	medium_impact	-0,47	high_impact	2,74	0,52	0,9	2,14	6,8	N	0,5	N	0,91	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7144	7144	T	A	MI.4533	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1241	414	F	Y	tTc/tAc	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,27	deleterious	-4,19	neutral	-1,48	high_impact	4,25	neutral	0,71	damaging	0,04	deleterious	4,3	24	0,18	0,55	neutral	0,3	disease	0,87	disease	0,58	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,64	low_impact	-1,48	high_impact	2,83	0,75	0,9	2,14	6,8	N	0,51	P	0,59	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7144	7144	T	C	MI.4534	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1241	414	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,28	deleterious	-3,65	deleterious	-3,93	high_impact	4,08	neutral	0,73	damaging	0,05	deleterious	4,39	24,1	0,11	0,55	disease	0,63	disease	0,9	disease	0,67	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,67	0,67	0,9	2,14	6,8	N	0,48	N	0,84	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7145	7145	C	A	MI.4535	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1242	414	F	L	ttC/ttA	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,38	neutral	-2,16	deleterious	-2,95	high_impact	4,02	neutral	0,72	damaging	0,04	deleterious	4,76	24,7	0,38	0,55	neutral	0,48	disease	0,87	disease	0,6	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,64	low_impact	-1,48	high_impact	2,61	0,8	0,9	2,14	6,8	N	0,51	P	0,83	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7145	7145	C	G	MI.4536	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1242	414	F	L	ttC/ttG	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	2,38	neutral	-2,16	deleterious	-2,95	high_impact	4,02	neutral	0,72	damaging	0,04	deleterious	4,48	24,2	0,38	0,55	neutral	0,48	disease	0,87	disease	0,6	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,64	low_impact	-1,48	high_impact	2,61	0,8	0,9	2,14	6,8	N	0,51	P	0,83	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7146	7146	A	G	MI.4537	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1243	415	T	A	Act/Gct	-3,8	0	0	benign	0,02	neutral	0,51	neutral	2,86	neutral	-0,07	neutral	-0,18	neutral_impact	0,1	neutral	0,9	neutral	1	deleterious	-0,04	2,19	0,4	0,55	neutral	0,17	neutral	0,22	neutral	0,3	neutral	0,4	2	neutral	0,46	deleterious	0,75	neutral	-6	neutral	0,1	medium_impact	0,83	medium_impact	0,2	low_impact	-1,01	0,68	0,9	14,23	27,59	N	0,3	N	0	polymorphism	1	0,01	rs372136420	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7146	7146	A	C	MI.4538	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1243	415	T	P	Act/Cct	-3,8	0	0	benign	0	neutral	0,2	neutral	2,77	neutral	-2,71	neutral	-1,09	low_impact	0,92	neutral	0,67	neutral	0,49	deleterious	0,65	8,51	0,12	0,55	neutral	0,49	disease	0,73	disease	0,55	disease	0,7	4	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,25	high_impact	2,07	medium_impact	-0,14	medium_impact	-0,25	0,69	0,9	14,23	27,59	N	0,35	N	0,2	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7146	7146	A	T	MI.4539	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1243	415	T	S	Act/Tct	-3,8	0	0	benign	0	neutral	0,4	neutral	2,81	neutral	-0,96	neutral	-0,34	neutral_impact	0,26	neutral	0,77	neutral	0,97	deleterious	-0,04	2,2	0,31	0,55	neutral	0,22	neutral	0,25	neutral	0,28	neutral	0,44	1	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,1	medium_impact	-0,86	0,83	0,9	14,23	27,59	N	0,44	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8740	8740	C	A	MI.454	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	214	72	L	M	Cta/Ata	-1,26	0	0	probably_damaging	1	neutral	0,09	neutral	4,28	deleterious	-3,07	neutral	-1,73	medium_impact	2,38	neutral	0,88	damaging	0,17	deleterious	3,58	23,2	0,33	0,65	disease	0,67	neutral	0,49	neutral	0,42	disease	0,53	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,28	medium_impact	0,94	0,75	0,9	27,88	11,58	N	0,38	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7147	7147	C	A	MI.4540	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1244	415	T	N	aCt/aAt	-0,33	0	0	benign	0,09	neutral	0,31	neutral	2,77	neutral	-2,12	neutral	-0,81	low_impact	1,54	neutral	0,6	neutral	0,58	deleterious	0,67	8,64	0,33	0,55	neutral	0,42	disease	0,51	neutral	0,4	neutral	0,49	0	neutral	0,65	deleterious	0,61	neutral	-6	neutral	0,2	medium_impact	0,19	medium_impact	0	medium_impact	0,32	0,83	0,9	14,23	27,59	N	0,47	N	0,2	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7147	7147	C	T	MI.4541	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1244	415	T	I	aCt/aTt	-0,33	0	0	benign	0	neutral	0,41	neutral	2,88	neutral	0,01	neutral	0,46	neutral_impact	-1,27	neutral	0,8	neutral	0,96	deleterious	0,05	3,06	0,22	0,55	neutral	0,18	neutral	0,31	neutral	0,19	neutral	0,44	1	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,11	low_impact	-2,27	0,77	0,9	14,23	27,59	N	0,43	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7147	7147	C	G	MI.4542	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1244	415	T	S	aCt/aGt	-0,33	0	0	benign	0	neutral	0,4	neutral	2,81	neutral	-0,96	neutral	-0,34	neutral_impact	0,26	neutral	0,77	neutral	0,97	deleterious	0,16	4,26	0,31	0,55	neutral	0,22	neutral	0,25	neutral	0,28	neutral	0,44	1	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,1	medium_impact	-0,86	0,83	0,9	14,23	27,59	N	0,43	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7149	7149	A	T	MI.4543	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1246	416	I	F	Atc/Ttc	-6,81	0	0	possibly_damaging	0,56	neutral	0,14	neutral	2,78	neutral	-0,33	neutral	-1,34	medium_impact	2,48	damaging	0,59	neutral	0,35	deleterious	3,66	23,2	0,28	0,55	neutral	0,3	disease	0,72	disease	0,6	disease	0,67	3	neutral	0,85	neutral	0,29	NA	0	deleterious	0,51	medium_impact	-0,86	medium_impact	-0,25	medium_impact	1,19	0,75	0,9	11,31	15,83	N	0,34	N	0,74	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7149	7149	A	G	MI.4544	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1246	416	I	V	Atc/Gtc	-6,81	0	0	benign	0	neutral	1	neutral	2,83	neutral	0,25	neutral	-0,06	neutral_impact	0,54	neutral	0,69	neutral	0,95	neutral	-1,29	0,01	0,46	0,55	neutral	0,27	neutral	0,15	neutral	0,31	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,07	high_impact	1,86	medium_impact	-0,6	0,63	0,9	11,31	15,83	N	0,38	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7149	7149	A	C	MI.4545	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1246	416	I	L	Atc/Ctc	-6,81	0	0	benign	0,08	neutral	0,93	neutral	3,16	neutral	1,97	neutral	-0,48	neutral_impact	0,08	neutral	0,71	neutral	0,68	deleterious	0,38	6,47	0,29	0,55	neutral	0,16	neutral	0,32	neutral	0,28	neutral	0,45	1	neutral	0,02	deleterious	0,93	neutral	-6	neutral	0,1	medium_impact	0,24	medium_impact	0,82	low_impact	-1,03	0,7	0,9	11,31	15,83	N	0,32	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7150	7150	T	G	MI.4546	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1247	416	I	S	aTc/aGc	0,82	0,67	0	possibly_damaging	0,8	neutral	0,09	neutral	2,75	neutral	-0,81	neutral	-1,42	neutral_impact	0,54	neutral	0,72	neutral	0,7	neutral	1,44	13,02	0,17	0,55	neutral	0,48	disease	0,58	neutral	0,42	neutral	0,48	0	neutral	0,94	neutral	0,15	neutral	-3	deleterious	0,54	low_impact	-1,32	medium_impact	-0,37	medium_impact	-0,6	0,7	0,9	11,31	15,83	N	0,36	N	0,56	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7150	7150	T	A	MI.4547	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1247	416	I	N	aTc/aAc	0,82	0,67	0	probably_damaging	0,95	deleterious	0	neutral	2,68	deleterious	-3,05	neutral	-2,02	medium_impact	2,89	neutral	0,65	neutral	0,4	deleterious	4,2	23,9	0,16	0,55	disease	0,65	disease	0,78	disease	0,62	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,75	low_impact	-1,96	low_impact	-1,48	medium_impact	1,57	0,74	0,9	11,31	15,83	N	0,27	N	0,75	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7150	7150	T	C	MI.4548	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1247	416	I	T	aTc/aCc	0,82	0,67	0	possibly_damaging	0,54	neutral	0,23	neutral	2,76	neutral	-0,64	neutral	-0,9	neutral_impact	0,23	neutral	0,74	neutral	0,75	neutral	-0,33	0,58	0,24	0,55	neutral	0,29	neutral	0,33	neutral	0,37	neutral	0,44	1	neutral	0,76	neutral	0,35	neutral	-3	neutral	0,3	medium_impact	-0,82	medium_impact	-0,1	medium_impact	-0,89	0,76	0,9	11,31	15,83	N	0,4	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7151	7151	C	G	MI.4549	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1248	416	I	M	atC/atG	5,91	0,97	0	possibly_damaging	0,8	neutral	0,16	neutral	2,79	neutral	-0,25	neutral	-0,63	low_impact	0,84	neutral	0,69	neutral	0,63	neutral	1,77	14,82	0,3	0,55	neutral	0,48	neutral	0,3	neutral	0,33	neutral	0,41	2	neutral	0,9	neutral	0,18	neutral	-3	deleterious	0,44	low_impact	-1,32	medium_impact	-0,21	medium_impact	-0,32	0,8	0,9	11,31	15,83	P	0,58	P	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8740	8740	C	G	MI.455	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	214	72	L	V	Cta/Gta	-1,26	0	0	probably_damaging	0,99	neutral	0,15	neutral	4,34	neutral	-1,48	deleterious	-2,63	low_impact	1,79	neutral	0,83	damaging	0,13	deleterious	3,29	22,8	0,32	0,65	neutral	0,38	disease	0,6	disease	0,61	disease	0,5	0	deleterious	0,99	neutral	0,08	neutral	-2	deleterious	0,73	low_impact	-2,65	medium_impact	-0,13	medium_impact	0,44	0,68	0,9	27,88	11,58	N	0,26	N	0,39	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7151	7151	C	A	MI.4550	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1248	416	I	M	atC/atA	5,91	0,97	0	possibly_damaging	0,8	neutral	0,16	neutral	2,79	neutral	-0,25	neutral	-0,63	low_impact	0,84	neutral	0,69	neutral	0,63	deleterious	2,3	18,16	0,3	0,55	neutral	0,48	neutral	0,3	neutral	0,33	neutral	0,41	2	neutral	0,9	neutral	0,18	neutral	-3	deleterious	0,44	low_impact	-1,32	medium_impact	-0,21	medium_impact	-0,32	0,8	0,9	11,31	15,83	P	0,59	P	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7152	7152	A	T	MI.4551	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1249	417	M	L	Ata/Tta	-8,89	0	0	benign	0,03	neutral	0,05	neutral	2,89	neutral	0,87	neutral	-1,39	medium_impact	2,25	damaging	0,56	neutral	0,45	neutral	1,68	14,28	0,4	0,55	neutral	0,21	disease	0,84	disease	0,53	disease	0,52	0	neutral	0,95	deleterious	0,51	neutral	-3	neutral	0,24	medium_impact	0,66	medium_impact	-0,52	medium_impact	0,98	0,6	0,9	7,02	13,9	N	0,37	N	0,61	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7152	7152	A	C	MI.4552	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1249	417	M	L	Ata/Cta	-8,89	0	0	benign	0,03	neutral	0,05	neutral	2,89	neutral	0,87	neutral	-1,39	medium_impact	2,25	damaging	0,56	neutral	0,45	neutral	1,61	13,89	0,4	0,55	neutral	0,21	disease	0,84	disease	0,53	disease	0,52	0	neutral	0,95	deleterious	0,51	neutral	-3	neutral	0,24	medium_impact	0,66	medium_impact	-0,52	medium_impact	0,98	0,6	0,9	7,02	13,9	N	0,37	N	0,61	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7152	7152	A	G	MI.4553	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1249	417	M	V	Ata/Gta	-8,89	0	0	benign	0,04	deleterious	0	neutral	2,83	neutral	0,51	neutral	-1,84	medium_impact	3,45	damaging	0,57	neutral	0,37	neutral	1,1	11,22	0,42	0,55	neutral	0,22	disease	0,9	disease	0,68	disease	0,75	5	deleterious	1	deleterious	0,48	deleterious	1	neutral	0,27	medium_impact	0,54	low_impact	-1,48	high_impact	2,09	0,59	0,9	7,02	13,9	N	0,36	N	0,88	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7153	7153	T	C	MI.4554	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1250	417	M	T	aTa/aCa	8,69	1	0	benign	0,01	neutral	0,09	neutral	2,82	neutral	1,33	deleterious	-2,68	low_impact	1,75	damaging	0,52	neutral	0,5	deleterious	0,11	3,68	0,3	0,55	neutral	0,25	disease	0,8	disease	0,55	disease	0,51	0	neutral	0,91	deleterious	0,54	neutral	-6	neutral	0,27	medium_impact	1,12	medium_impact	-0,37	medium_impact	0,52	0,4	0,9	7,02	13,9	P	0,56	P	0,79	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7153	7153	T	A	MI.4555	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1250	417	M	K	aTa/aAa	8,69	1	0	benign	0,09	deleterious	0	neutral	2,7	neutral	-1,82	deleterious	-2,78	high_impact	4,73	damaging	0,58	neutral	0,37	deleterious	2,29	18,11	0,2	0,55	disease	0,56	disease	0,95	disease	0,8	disease	0,91	8	deleterious	1	neutral	0,46	deleterious	2	neutral	0,41	medium_impact	0,19	low_impact	-1,48	high_impact	3,27	0,62	0,9	7,02	13,9	P	0,68	P	0,93	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7154	7154	A	T	MI.4556	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1251	417	M	I	atA/atT	4,76	1	0	benign	0,09	deleterious	0	neutral	2,82	neutral	0,22	neutral	-1,86	medium_impact	3,49	damaging	0,54	neutral	0,45	neutral	1,74	14,62	0,43	0,55	neutral	0,21	disease	0,9	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,46	deleterious	1	neutral	0,31	medium_impact	0,19	low_impact	-1,48	high_impact	2,12	0,62	0,9	7,02	13,9	P	0,53	P	0,87	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7154	7154	A	C	MI.4557	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1251	417	M	I	atA/atC	4,76	1	0	benign	0,09	deleterious	0	neutral	2,82	neutral	0,22	neutral	-1,86	medium_impact	3,49	damaging	0,54	neutral	0,45	neutral	1,65	14,12	0,43	0,55	neutral	0,21	disease	0,9	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,46	deleterious	1	neutral	0,31	medium_impact	0,19	low_impact	-1,48	high_impact	2,12	0,62	0,9	7,02	13,9	P	0,54	P	0,87	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7155	7155	T	C	MI.4558	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1252	418	F	L	Ttc/Ctc	0,59	0,99	0	probably_damaging	0,98	deleterious	0	neutral	2,74	neutral	-1,41	deleterious	-2,88	medium_impact	3,01	neutral	0,74	damaging	0,07	deleterious	4,21	23,9	0,32	0,55	neutral	0,2	disease	0,83	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,72	low_impact	-2,35	low_impact	-1,48	medium_impact	1,68	0,77	0,9	2,14	6,77	N	0,38	N	0,83	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7155	7155	T	A	MI.4559	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1252	418	F	I	Ttc/Atc	0,59	0,99	0	probably_damaging	0,99	deleterious	0	neutral	2,68	neutral	-2,15	deleterious	-2,88	high_impact	4,31	neutral	0,72	damaging	0,08	deleterious	4,55	24,3	0,19	0,55	neutral	0,41	disease	0,88	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,64	low_impact	-1,48	high_impact	2,88	0,64	0,9	2,14	6,77	N	0,43	N	0,88	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8741	8741	T	G	MI.456	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	215	72	L	R	cTa/cGa	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	4,23	deleterious	-4,81	deleterious	-5,32	high_impact	3,82	neutral	0,79	damaging	0,12	deleterious	4,08	23,7	0,13	0,65	disease	0,79	disease	0,9	disease	0,73	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,18	0,66	0,9	27,88	11,58	N	0,36	N	1	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	T8741G	MILS protective factor	-	+	Reported	1
chrM	7155	7155	T	G	MI.4560	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1252	418	F	V	Ttc/Gtc	0,59	0,99	0	probably_damaging	1	deleterious	0,03	neutral	2,72	neutral	-1,93	deleterious	-3,36	high_impact	3,76	neutral	0,7	damaging	0,07	deleterious	4,23	23,9	0,21	0,55	neutral	0,45	disease	0,9	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-3,58	medium_impact	-0,65	high_impact	2,37	0,65	0,9	2,14	6,77	N	0,37	N	0,84	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7156	7156	T	A	MI.4561	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1253	418	F	Y	tTc/tAc	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,62	deleterious	-3,98	neutral	-1,44	high_impact	4,11	neutral	0,7	damaging	0,06	deleterious	4,53	24,3	0,26	0,55	disease	0,72	disease	0,84	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,35	low_impact	-1,48	high_impact	2,7	0,65	0,9	2,14	6,77	P	0,55	P	0,59	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7156	7156	T	G	MI.4562	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1253	418	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-4,74	deleterious	-3,84	high_impact	5	neutral	0,71	damaging	0,06	deleterious	4,25	23,9	0,19	0,55	disease	0,82	disease	0,89	disease	0,73	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,39	0,9	2,14	6,77	P	0,72	P	0,91	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7156	7156	T	C	MI.4563	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1253	418	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	2,69	deleterious	-3,39	deleterious	-3,84	high_impact	4,46	neutral	0,73	damaging	0,08	deleterious	4,48	24,2	0,2	0,55	disease	0,51	disease	0,87	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-3,58	medium_impact	-0,92	high_impact	3,02	0,65	0,9	2,14	6,77	N	0,51	P	0,84	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7157	7157	C	G	MI.4564	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1254	418	F	L	ttC/ttG	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,74	neutral	-1,41	deleterious	-2,88	medium_impact	3,01	neutral	0,74	damaging	0,07	deleterious	4,5	24,3	0,32	0,55	neutral	0,2	disease	0,83	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,72	low_impact	-2,35	low_impact	-1,48	medium_impact	1,68	0,77	0,9	2,14	6,77	N	0,49	N	0,83	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7157	7157	C	A	MI.4565	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1254	418	F	L	ttC/ttA	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,74	neutral	-1,41	deleterious	-2,88	medium_impact	3,01	neutral	0,74	damaging	0,07	deleterious	4,83	24,8	0,32	0,55	neutral	0,2	disease	0,83	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,72	low_impact	-2,35	low_impact	-1,48	medium_impact	1,68	0,77	0,9	2,14	6,77	N	0,5	N	0,83	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7158	7158	A	T	MI.4566	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1255	419	I	F	Atc/Ttc	-0,57	0	0	benign	0,14	neutral	0,07	neutral	2,5	neutral	-2,72	neutral	-1,49	medium_impact	2,19	neutral	0,72	neutral	0,69	deleterious	0,79	9,42	0,27	0,55	neutral	0,46	disease	0,73	neutral	0,45	disease	0,53	1	neutral	0,92	neutral	0,47	neutral	-3	neutral	0,26	medium_impact	-0,01	medium_impact	-0,43	medium_impact	0,92	0,81	0,9	14,62	17,04	N	0,45	N	0,61	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7158	7158	A	G	MI.4567	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1255	419	I	V	Atc/Gtc	-0,57	0	0	benign	0	neutral	0,8	neutral	2,69	neutral	-0,51	neutral	-0,22	neutral_impact	0,74	neutral	0,83	neutral	1	neutral	-0,61	0,12	0,54	0,6	neutral	0,26	neutral	0,2	neutral	0,38	neutral	0,35	3	neutral	0,19	deleterious	0,9	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,53	medium_impact	-0,42	0,68	0,9	14,62	17,04	N	0,39	N	0	polymorphism	1	0,02	rs878887002	.	.	.	.	.	.	.	89,91	A7158G	Prostate Cancer	+	-	Reported	1
chrM	7158	7158	A	C	MI.4568	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1255	419	I	L	Atc/Ctc	-0,57	0	0	benign	0,01	neutral	0,4	neutral	2,67	neutral	-1,22	neutral	-0,48	low_impact	0,86	neutral	0,68	neutral	0,82	deleterious	0,28	5,51	0,37	0,55	neutral	0,31	neutral	0,34	neutral	0,36	neutral	0,44	1	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,12	medium_impact	1,12	medium_impact	0,1	medium_impact	-0,31	0,77	0,9	14,62	17,04	N	0,44	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7159	7159	T	C	MI.4569	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1256	419	I	T	aTc/aCc	0,13	0	0	benign	0	neutral	0,08	neutral	2,48	neutral	-2,91	neutral	-1,62	medium_impact	2,28	neutral	0,69	neutral	0,83	deleterious	0,32	5,86	0,37	0,55	neutral	0,23	disease	0,56	neutral	0,48	neutral	0,46	1	neutral	0,92	deleterious	0,54	neutral	-3	neutral	0,14	high_impact	2,07	medium_impact	-0,4	medium_impact	1,01	0,71	0,9	14,62	17,04	P	0,49	N	0,51	polymorphism	1	0,05	rs3929989	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8741	8741	T	C	MI.457	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	215	72	L	P	cTa/cCa	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	4,22	deleterious	-5,38	deleterious	-6,26	medium_impact	3,48	neutral	0,81	damaging	0,12	deleterious	3,83	23,4	0,15	0,65	disease	0,84	disease	0,88	disease	0,74	disease	0,79	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	medium_impact	1,89	0,61	0,9	27,88	11,58	N	0,27	N	0,89	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7159	7159	T	G	MI.4570	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1256	419	I	S	aTc/aGc	0,13	0	0	benign	0,09	deleterious	0	neutral	2,49	deleterious	-3,42	neutral	-2,22	medium_impact	3,46	neutral	0,72	neutral	0,47	deleterious	2,52	19,56	0,25	0,55	neutral	0,41	disease	0,79	disease	0,65	disease	0,73	5	deleterious	1	neutral	0,46	deleterious	1	neutral	0,22	medium_impact	0,19	low_impact	-1,48	high_impact	2,1	0,66	0,9	14,62	17,04	N	0,41	N	0,52	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7159	7159	T	A	MI.4571	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1256	419	I	N	aTc/aAc	0,13	0	0	benign	0,14	deleterious	0	neutral	2,44	deleterious	-4,72	deleterious	-2,71	high_impact	4	neutral	0,69	neutral	0,38	deleterious	2,72	20,9	0,26	0,55	disease	0,66	disease	0,82	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,43	deleterious	2	neutral	0,31	medium_impact	-0,01	low_impact	-1,48	high_impact	2,59	0,71	0,9	14,62	17,04	N	0,39	N	0,65	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7160	7160	C	A	MI.4572	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1257	419	I	M	atC/atA	0,82	0	0	benign	0,02	deleterious	0,02	neutral	2,47	deleterious	-3,34	neutral	-0,87	medium_impact	2,68	neutral	0,71	neutral	0,69	neutral	0,93	10,24	0,36	0,55	disease	0,54	neutral	0,44	disease	0,56	disease	0,62	2	neutral	0,98	deleterious	0,5	deleterious	1	neutral	0,15	medium_impact	0,83	medium_impact	-0,75	medium_impact	1,38	0,85	0,9	14,62	17,04	N	0,43	N	0,01	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7160	7160	C	G	MI.4573	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1257	419	I	M	atC/atG	0,82	0	0	benign	0,02	deleterious	0,02	neutral	2,47	deleterious	-3,34	neutral	-0,87	medium_impact	2,68	neutral	0,71	neutral	0,69	deleterious	0,42	6,78	0,36	0,55	disease	0,54	neutral	0,44	disease	0,56	disease	0,62	2	neutral	0,98	deleterious	0,5	deleterious	1	neutral	0,15	medium_impact	0,83	medium_impact	-0,75	medium_impact	1,38	0,85	0,9	14,62	17,04	N	0,43	N	0,01	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7161	7161	G	C	MI.4574	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1258	420	G	R	Ggc/Cgc	-5,42	0	0	probably_damaging	1	deleterious	0	neutral	0,53	deleterious	-9,66	deleterious	-3,65	high_impact	5,05	damaging	0,4	damaging	0,01	deleterious	4,04	23,7	0,1	0,55	disease	0,9	disease	0,89	disease	0,77	disease	0,86	7	deleterious	1	deleterious	0	deleterious	6	deleterious	0,91	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,73	0,9	NA	NA	P	0,51	P	0,95	polymorphism	0,65	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7161	7161	G	T	MI.4575	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1258	420	G	C	Ggc/Tgc	-5,42	0	0	probably_damaging	1	deleterious	0	neutral	0,52	deleterious	-10,99	deleterious	-4,1	high_impact	5,05	damaging	0,36	damaging	0,01	deleterious	4,26	23,9	0,15	0,55	disease	0,97	disease	0,87	disease	0,66	disease	0,83	7	deleterious	1	deleterious	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,59	0,9	NA	NA	N	0,45	N	0,98	disease_causing	0,51	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7161	7161	G	A	MI.4576	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1258	420	G	S	Ggc/Agc	-5,42	0	0	probably_damaging	1	deleterious	0,01	neutral	0,58	deleterious	-6,84	deleterious	-2,68	medium_impact	2,98	damaging	0,43	damaging	0,03	deleterious	4,28	24	0,22	0,55	disease	0,81	disease	0,75	disease	0,58	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,85	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,65	0,74	0,9	NA	NA	N	0,31	N	0,73	polymorphism	0,8	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7162	7162	G	C	MI.4577	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1259	420	G	A	gGc/gCc	6,14	1	0	probably_damaging	1	deleterious	0,03	neutral	0,58	deleterious	-6,67	deleterious	-2,68	high_impact	4,01	damaging	0,53	damaging	0,05	deleterious	3,3	22,9	0,27	0,55	disease	0,81	disease	0,6	disease	0,56	disease	0,6	2	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-3,58	medium_impact	-0,65	high_impact	2,6	0,75	0,9	NA	NA	P	0,48	N	0,64	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7162	7162	G	A	MI.4578	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1259	420	G	D	gGc/gAc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	0,53	deleterious	-9,04	deleterious	-3,2	high_impact	5,05	damaging	0,28	damaging	0,01	deleterious	3,97	23,6	0,11	0,55	disease	0,71	disease	0,84	disease	0,76	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,51	0,9	NA	NA	P	0,8	P	0,97	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7162	7162	G	T	MI.4579	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1259	420	G	V	gGc/gTc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	0,53	deleterious	-10,24	deleterious	-4,11	high_impact	4,7	damaging	0,44	damaging	0,02	deleterious	3,95	23,6	0,16	0,55	disease	0,92	disease	0,87	disease	0,68	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,24	0,61	0,9	NA	NA	P	0,56	P	0,93	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8741	8741	T	A	MI.458	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	215	72	L	Q	cTa/cAa	-3,34	0	0	probably_damaging	1	deleterious	0	neutral	4,23	deleterious	-4,98	deleterious	-5,32	medium_impact	2,62	neutral	0,82	damaging	0,13	deleterious	4,24	23,9	0,18	0,65	disease	0,8	disease	0,8	disease	0,62	disease	0,72	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,83	low_impact	-3,6	low_impact	-1,4	medium_impact	1,15	0,69	0,9	27,88	11,58	N	0,25	N	0,91	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7164	7164	G	A	MI.4580	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1261	421	V	M	Gta/Ata	-14,45	0	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-0,18	neutral	-1,41	high_impact	4,91	neutral	0,63	damaging	0,13	deleterious	3,86	23,5	0,38	0,55	neutral	0,21	disease	0,67	disease	0,64	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,67	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,97	1	5,07	8,43	P	0,65	P	0,82	polymorphism	0,94	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7164	7164	G	C	MI.4581	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1261	421	V	L	Gta/Cta	-14,45	0	0	probably_damaging	0,99	deleterious	0,01	neutral	2,8	neutral	-0,09	neutral	-1,41	high_impact	4,01	damaging	0,57	damaging	0,12	deleterious	3,77	23,4	0,34	0,55	neutral	0,29	disease	0,69	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,64	medium_impact	-0,92	high_impact	2,6	0,77	0,9	5,07	8,43	N	0,31	N	0,55	polymorphism	0,95	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7164	7164	G	T	MI.4582	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1261	421	V	L	Gta/Tta	-14,45	0	0	probably_damaging	0,99	deleterious	0,01	neutral	2,8	neutral	-0,09	neutral	-1,41	high_impact	4,01	damaging	0,57	damaging	0,12	deleterious	3,89	23,5	0,34	0,55	neutral	0,29	disease	0,69	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,64	medium_impact	-0,92	high_impact	2,6	0,77	0,9	5,07	8,43	N	0,31	N	0,55	polymorphism	0,95	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7165	7165	T	A	MI.4583	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1262	421	V	E	gTa/gAa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-3,54	deleterious	-2,81	high_impact	4,57	damaging	0,56	damaging	0,13	deleterious	4,83	24,8	0,1	0,55	disease	0,66	disease	0,83	disease	0,75	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,12	0,58	0,9	5,07	8,43	P	0,55	P	0,84	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7165	7165	T	C	MI.4584	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1262	421	V	A	gTa/gCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-1,09	neutral	-1,87	high_impact	3,59	damaging	0,5	damaging	0,14	deleterious	3,74	23,3	0,31	0,55	neutral	0,33	disease	0,5	disease	0,58	neutral	0,46	1	deleterious	1	neutral	0	deleterious	6	deleterious	0,71	low_impact	-3,58	low_impact	-1,48	high_impact	2,22	0,68	0,9	5,07	8,43	P	0,56	P	0,47	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7165	7165	T	G	MI.4585	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1262	421	V	G	gTa/gGa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,64	neutral	-2,54	deleterious	-3,28	high_impact	4,57	damaging	0,57	damaging	0,13	deleterious	3,98	23,6	0,14	0,55	disease	0,65	disease	0,75	disease	0,64	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	3,12	0,63	0,9	5,07	8,43	P	0,52	P	0,71	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7167	7167	A	G	MI.4586	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1264	422	N	D	Aat/Gat	-7,97	0	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-3,74	neutral	-2,29	high_impact	4,99	damaging	0,53	damaging	0,06	deleterious	4	23,6	0,47	0,55	disease	0,7	disease	0,75	disease	0,72	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,51	0,6	0,9	NA	NA	P	0,65	P	0,92	polymorphism	0,99	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7167	7167	A	T	MI.4587	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1264	422	N	Y	Aat/Tat	-7,97	0	0	probably_damaging	1	deleterious	0	neutral	2,63	neutral	-0,84	deleterious	-3,66	high_impact	3,94	neutral	0,6	damaging	0,05	deleterious	3,88	23,5	0,21	0,55	disease	0,64	disease	0,89	disease	0,69	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,54	0,48	0,9	NA	NA	N	0,27	N	0,93	polymorphism	0,89	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7167	7167	A	C	MI.4588	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1264	422	N	H	Aat/Cat	-7,97	0	0	probably_damaging	1	deleterious	0	neutral	2,63	neutral	-2,38	neutral	-2,29	medium_impact	3,03	neutral	0,61	damaging	0,05	deleterious	3,23	22,8	0,31	0,55	disease	0,54	disease	0,84	disease	0,73	disease	0,78	6	deleterious	1	neutral	0	deleterious	5	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	medium_impact	1,7	0,55	0,9	NA	NA	N	0,24	N	0,83	polymorphism	0,97	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7168	7168	A	G	MI.4589	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1265	422	N	S	aAt/aGt	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,66	neutral	-2,1	neutral	-2,29	high_impact	4,09	neutral	0,62	damaging	0,06	deleterious	3,21	22,7	0,5	0,55	disease	0,59	disease	0,76	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,64	low_impact	-1,48	high_impact	2,68	0,38	0,9	NA	NA	P	0,48	N	0,79	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8743	8743	G	C	MI.459	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	217	73	V	L	Gta/Cta	-4,04	0	0	benign	0,01	neutral	0,6	neutral	4,43	neutral	0,21	neutral	-0,47	neutral_impact	-0,04	neutral	0,92	neutral	0,83	deleterious	0,22	4,9	0,48	0,65	neutral	0,25	neutral	0,42	neutral	0,32	neutral	0,44	1	neutral	0,39	deleterious	0,8	neutral	-6	neutral	0,15	medium_impact	1,14	medium_impact	0,39	low_impact	-1,13	0,72	0,9	25,22	18,16	N	0,28	N	0,28	polymorphism	1	0,02	rs386829047	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7168	7168	A	T	MI.4590	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1265	422	N	I	aAt/aTt	8,69	1	0	probably_damaging	1	deleterious	0,01	neutral	2,71	neutral	-1,11	deleterious	-4,12	high_impact	4,18	neutral	0,63	damaging	0,06	deleterious	3,95	23,6	0,21	0,55	disease	0,64	disease	0,92	disease	0,68	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-3,58	medium_impact	-0,92	high_impact	2,76	0,48	0,9	NA	NA	P	0,5	N	0,98	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7168	7168	A	C	MI.4591	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1265	422	N	T	aAt/aCt	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,65	neutral	-1,45	deleterious	-2,75	high_impact	4,18	neutral	0,64	damaging	0,06	deleterious	3,5	23,1	0,36	0,55	disease	0,61	disease	0,81	disease	0,7	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,76	0,53	0,9	NA	NA	P	0,48	N	0,59	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7169	7169	T	G	MI.4592	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1266	422	N	K	aaT/aaG	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,61	neutral	-2,73	deleterious	-2,75	high_impact	4,18	damaging	0,59	damaging	0,04	deleterious	4,21	23,9	0,47	0,55	disease	0,58	disease	0,86	disease	0,74	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,76	0,8	0,9	NA	NA	P	0,54	P	0,92	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7169	7169	T	A	MI.4593	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1266	422	N	K	aaT/aaA	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,61	neutral	-2,73	deleterious	-2,75	high_impact	4,18	damaging	0,59	damaging	0,04	deleterious	4,53	24,3	0,47	0,55	disease	0,58	disease	0,86	disease	0,74	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,76	0,8	0,9	NA	NA	P	0,57	P	0,92	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7170	7170	C	A	MI.4594	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1267	423	L	M	Cta/Ata	-2,42	0	0	benign	0,09	neutral	0,29	neutral	2,43	deleterious	-3,01	neutral	-0,28	neutral_impact	0,78	neutral	0,7	neutral	0,97	deleterious	0,62	8,28	0,36	0,55	neutral	0,31	neutral	0,21	neutral	0,33	neutral	0,35	3	neutral	0,67	deleterious	0,6	neutral	-6	neutral	0,14	medium_impact	0,19	medium_impact	-0,02	medium_impact	-0,38	0,69	0,9	13,65	24,37	N	0,46	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7170	7170	C	G	MI.4595	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1267	423	L	V	Cta/Gta	-2,42	0	0	benign	0,33	deleterious	0,01	neutral	2,56	neutral	-1,35	neutral	-0,85	medium_impact	2,8	damaging	0,6	neutral	0,43	neutral	0,9	10,06	0,36	0,55	neutral	0,22	disease	0,55	neutral	0,37	neutral	0,45	1	deleterious	0,99	neutral	0,34	deleterious	1	neutral	0,26	medium_impact	-0,47	medium_impact	-0,92	medium_impact	1,49	0,56	0,9	13,65	24,37	N	0,44	N	0,27	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7171	7171	T	C	MI.4596	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1268	423	L	P	cTa/cCa	-3,34	0	0	probably_damaging	0,92	deleterious	0	neutral	2,39	deleterious	-5,1	deleterious	-2,64	high_impact	4,48	damaging	0,53	damaging	0,19	deleterious	3,99	23,6	0,12	0,55	disease	0,74	disease	0,86	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,82	low_impact	-1,76	low_impact	-1,48	high_impact	3,04	0,52	0,9	13,65	24,37	N	0,44	N	0,88	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7171	7171	T	A	MI.4597	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1268	423	L	Q	cTa/cAa	-3,34	0	0	possibly_damaging	0,86	deleterious	0	neutral	2,39	deleterious	-4,7	neutral	-2,15	high_impact	4,48	damaging	0,6	damaging	0,21	deleterious	4,09	23,7	0,14	0,55	disease	0,69	disease	0,81	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,68	low_impact	-1,5	low_impact	-1,48	high_impact	3,04	0,71	0,9	13,65	24,37	N	0,43	N	0,63	polymorphism	0,99	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7171	7171	T	G	MI.4598	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1268	423	L	R	cTa/cGa	-3,34	0	0	possibly_damaging	0,86	deleterious	0	neutral	2,39	deleterious	-4,52	neutral	-2,27	high_impact	4,48	damaging	0,57	damaging	0,15	deleterious	4,22	23,9	0,12	0,55	disease	0,66	disease	0,93	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,75	low_impact	-1,5	low_impact	-1,48	high_impact	3,04	0,61	0,9	13,65	24,37	N	0,45	N	0,71	polymorphism	0,99	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7173	7173	A	G	MI.4599	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1270	424	T	A	Act/Gct	-1,26	0	0	probably_damaging	0,99	deleterious	0	neutral	2,68	neutral	-1,06	neutral	-2,27	high_impact	4,24	neutral	0,75	damaging	0,1	deleterious	3,66	23,2	0,48	0,55	neutral	0,29	disease	0,64	disease	0,63	disease	0,58	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,69	low_impact	-2,64	low_impact	-1,48	high_impact	2,82	0,74	0,9	NA	NA	N	0,38	N	0,69	disease_causing	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8546	8546	C	T	MI.46	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	20	7	A	V	gCt/gTt	-0,33	0	0	benign	0,06	deleterious	0	neutral	4,63	neutral	-1,01	neutral	-1,69	low_impact	1,36	neutral	0,88	neutral	0,59	deleterious	2,72	20,9	0,39	0,65	neutral	0,19	disease	0,51	neutral	0,5	disease	0,53	1	deleterious	1	deleterious	0,47	neutral	-2	neutral	0,17	medium_impact	0,38	low_impact	-1,4	medium_impact	0,07	0,63	0,9	9,29	10,06	N	0,48	N	0,49	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8743	8743	G	A	MI.460	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	217	73	V	M	Gta/Ata	-4,04	0	0	benign	0,01	neutral	0,34	neutral	4,22	neutral	-1,86	neutral	0,03	neutral_impact	0,26	neutral	0,9	neutral	0,87	neutral	-0,37	0,46	0,45	0,65	neutral	0,49	neutral	0,25	neutral	0,3	neutral	0,41	2	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,16	medium_impact	1,14	medium_impact	0,13	medium_impact	-0,88	0,77	0,9	25,22	18,16	N	0,44	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7173	7173	A	C	MI.4600	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1270	424	T	P	Act/Cct	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-4,24	deleterious	-2,73	high_impact	5,04	neutral	0,64	damaging	0,08	deleterious	3,64	23,2	0,14	0,55	disease	0,72	disease	0,83	disease	0,8	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,73	0,9	NA	NA	P	0,73	P	0,92	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7173	7173	A	T	MI.4601	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1270	424	T	S	Act/Tct	-1,26	0	0	probably_damaging	0,99	deleterious	0	neutral	2,59	neutral	-2,69	neutral	-1,82	high_impact	4,7	neutral	0,74	damaging	0,08	deleterious	3,47	23	0,43	0,55	neutral	0,48	disease	0,69	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,64	low_impact	-1,48	high_impact	3,24	0,78	0,9	NA	NA	N	0,54	P	0,79	disease_causing	0,96	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7174	7174	C	G	MI.4602	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1271	424	T	S	aCt/aGt	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	2,59	neutral	-2,69	neutral	-1,82	high_impact	4,7	neutral	0,74	damaging	0,08	deleterious	3,62	23,2	0,43	0,55	neutral	0,48	disease	0,69	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,64	low_impact	-1,48	high_impact	3,24	0,78	0,9	NA	NA	P	0,6	P	0,79	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7174	7174	C	T	MI.4603	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1271	424	T	I	aCt/aTt	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,67	neutral	-1,13	deleterious	-2,73	high_impact	3,76	neutral	0,72	damaging	0,06	deleterious	4,03	23,7	0,35	0,55	neutral	0,44	disease	0,85	disease	0,63	disease	0,52	0	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,37	0,77	0,9	NA	NA	N	0,46	N	0,92	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7174	7174	C	A	MI.4604	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1271	424	T	N	aCt/aAt	8,69	1	0	probably_damaging	1	deleterious	0	neutral	2,57	deleterious	-3,56	neutral	-2,27	high_impact	4,35	neutral	0,69	damaging	0,06	deleterious	3,87	23,5	0,38	0,55	disease	0,6	disease	0,82	disease	0,7	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,92	0,81	0,9	NA	NA	N	0,49	N	0,8	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7176	7176	T	C	MI.4605	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1273	425	F	L	Ttc/Ctc	-10,51	0	0	probably_damaging	1	deleterious	0	neutral	2,51	neutral	-2,08	deleterious	-2,6	high_impact	4,72	damaging	0,58	damaging	0,19	deleterious	4,23	23,9	0,36	0,55	disease	0,52	disease	0,8	disease	0,74	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,26	0,81	0,9	2,53	7,02	P	0,64	P	0,83	polymorphism	0,8	0,4	rs878929873	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7176	7176	T	G	MI.4606	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1273	425	F	V	Ttc/Gtc	-10,51	0	0	probably_damaging	1	deleterious	0	neutral	2,58	neutral	-1,26	deleterious	-3,03	high_impact	5,07	neutral	0,65	damaging	0,15	deleterious	4,3	24	0,24	0,55	disease	0,56	disease	0,88	disease	0,77	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,58	0,57	0,9	2,53	7,02	P	0,73	P	0,84	polymorphism	0,68	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7176	7176	T	A	MI.4607	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1273	425	F	I	Ttc/Atc	-10,51	0	0	probably_damaging	1	deleterious	0	neutral	2,53	neutral	-1,82	deleterious	-2,6	high_impact	4,38	neutral	0,72	damaging	0,18	deleterious	4,59	24,4	0,18	0,55	disease	0,6	disease	0,87	disease	0,77	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,95	0,64	0,9	2,53	7,02	N	0,48	N	0,88	polymorphism	0,82	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7177	7177	T	C	MI.4608	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1274	425	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,51	neutral	-2,07	deleterious	-3,46	high_impact	4,52	neutral	0,77	damaging	0,19	deleterious	4,4	24,1	0,22	0,55	neutral	0,49	disease	0,84	disease	0,73	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,07	0,54	0,9	2,53	7,02	P	0,53	P	0,84	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7177	7177	T	G	MI.4609	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1274	425	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-4,78	deleterious	-3,47	high_impact	5,07	neutral	0,68	damaging	0,16	deleterious	4,27	23,9	0,24	0,55	disease	0,85	disease	0,88	disease	0,79	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,58	0,39	0,9	2,53	7,02	P	0,73	P	0,91	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8743	8743	G	T	MI.461	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	217	73	V	L	Gta/Tta	-4,04	0	0	benign	0,01	neutral	0,6	neutral	4,43	neutral	0,21	neutral	-0,47	neutral_impact	-0,04	neutral	0,92	neutral	0,83	deleterious	0,38	6,45	0,48	0,65	neutral	0,25	neutral	0,42	neutral	0,32	neutral	0,44	1	neutral	0,39	deleterious	0,8	neutral	-6	neutral	0,15	medium_impact	1,14	medium_impact	0,39	low_impact	-1,13	0,72	0,9	25,22	18,16	N	0,28	N	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7177	7177	T	A	MI.4610	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1274	425	F	Y	tTc/tAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	2,46	neutral	-2,91	neutral	-1,3	high_impact	4,17	neutral	0,7	damaging	0,15	deleterious	4,43	24,2	0,22	0,55	disease	0,55	disease	0,82	disease	0,73	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,75	0,68	0,9	2,53	7,02	P	0,57	P	0,59	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7178	7178	C	G	MI.4611	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1275	425	F	L	ttC/ttG	4,76	1	0	probably_damaging	1	deleterious	0	neutral	2,51	neutral	-2,08	deleterious	-2,6	high_impact	4,72	damaging	0,58	damaging	0,19	deleterious	4,54	24,3	0,36	0,55	disease	0,52	disease	0,8	disease	0,74	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,26	0,81	0,9	2,53	7,02	P	0,72	P	0,83	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7178	7178	C	A	MI.4612	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1275	425	F	L	ttC/ttA	4,76	1	0	probably_damaging	1	deleterious	0	neutral	2,51	neutral	-2,08	deleterious	-2,6	high_impact	4,72	damaging	0,58	damaging	0,19	deleterious	4,82	24,8	0,36	0,55	disease	0,52	disease	0,8	disease	0,74	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,26	0,81	0,9	2,53	7,02	P	0,72	P	0,83	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7179	7179	T	G	MI.4613	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1276	426	F	V	Ttc/Gtc	-0,57	0,16	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-1,46	deleterious	-2,97	high_impact	4,92	neutral	0,73	damaging	0,07	deleterious	4,19	23,8	0,33	0,55	neutral	0,32	disease	0,89	disease	0,72	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,68	0,9	2,53	6,61	P	0,67	P	0,84	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7179	7179	T	A	MI.4614	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1276	426	F	I	Ttc/Atc	-0,57	0,16	0	probably_damaging	0,99	deleterious	0,03	neutral	2,68	neutral	-1,86	deleterious	-2,54	high_impact	3,88	neutral	0,75	damaging	0,07	deleterious	4,49	24,3	0,24	0,55	neutral	0,24	disease	0,86	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,76	low_impact	-2,64	medium_impact	-0,65	high_impact	2,48	0,64	0,9	2,53	6,61	N	0,36	N	0,88	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7179	7179	T	C	MI.4615	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1276	426	F	L	Ttc/Ctc	-0,57	0,16	0	probably_damaging	0,98	deleterious	0	neutral	2,84	neutral	-0,97	deleterious	-2,54	medium_impact	2,69	neutral	0,75	damaging	0,06	deleterious	4,15	23,8	0,42	0,55	neutral	0,21	disease	0,79	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,73	low_impact	-2,35	low_impact	-1,48	medium_impact	1,39	0,81	0,9	2,53	6,61	N	0,32	N	0,83	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7180	7180	T	C	MI.4616	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1277	426	F	S	tTc/tCc	5,91	1	0	probably_damaging	1	deleterious	0,01	neutral	2,59	deleterious	-3,14	deleterious	-3,39	high_impact	4,38	neutral	0,76	damaging	0,08	deleterious	4,42	24,2	0,23	0,55	disease	0,59	disease	0,85	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-3,58	medium_impact	-0,92	high_impact	2,95	0,59	0,9	2,53	6,61	N	0,5	N	0,84	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7180	7180	T	A	MI.4617	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1277	426	F	Y	tTc/tAc	5,91	1	0	probably_damaging	0,98	deleterious	0	neutral	2,62	neutral	-2,75	neutral	-1,27	high_impact	4,12	neutral	0,74	damaging	0,07	deleterious	4,44	24,2	0,32	0,55	neutral	0,43	disease	0,82	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,35	low_impact	-1,48	high_impact	2,71	0,77	0,9	2,53	6,61	N	0,54	P	0,59	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7180	7180	T	G	MI.4618	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1277	426	F	C	tTc/tGc	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,56	deleterious	-4,44	deleterious	-3,4	high_impact	4,92	neutral	0,75	damaging	0,06	deleterious	4,29	24	0,27	0,55	disease	0,76	disease	0,89	disease	0,74	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,44	0,9	2,53	6,61	P	0,72	P	0,91	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7181	7181	C	G	MI.4619	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1278	426	F	L	ttC/ttG	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,84	neutral	-0,97	deleterious	-2,54	medium_impact	2,69	neutral	0,75	damaging	0,06	deleterious	4,56	24,4	0,42	0,55	neutral	0,21	disease	0,79	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,73	low_impact	-2,35	low_impact	-1,48	medium_impact	1,39	0,81	0,9	2,53	6,61	N	0,5	N	0,83	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8744	8744	T	C	MI.462	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	218	73	V	A	gTa/gCa	0,82	0	0	benign	0,03	neutral	0,51	neutral	4,26	neutral	-0,18	neutral	-0,91	neutral_impact	0,1	neutral	0,87	neutral	0,77	neutral	-0,2	1,08	0,37	0,65	neutral	0,39	neutral	0,21	neutral	0,35	neutral	0,37	3	neutral	0,46	deleterious	0,74	neutral	-6	neutral	0,16	medium_impact	0,68	medium_impact	0,3	low_impact	-1,01	0,57	0,9	25,22	18,16	N	0,28	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7181	7181	C	A	MI.4620	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1278	426	F	L	ttC/ttA	7,53	1	0	probably_damaging	0,98	deleterious	0	neutral	2,84	neutral	-0,97	deleterious	-2,54	medium_impact	2,69	neutral	0,75	damaging	0,06	deleterious	4,84	24,8	0,42	0,55	neutral	0,21	disease	0,79	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,73	low_impact	-2,35	low_impact	-1,48	medium_impact	1,39	0,81	0,9	2,53	6,61	N	0,5	N	0,83	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7182	7182	C	A	MI.4621	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1279	427	P	T	Cca/Aca	-0,8	0,02	0	probably_damaging	1	deleterious	0	neutral	2,73	neutral	-2,01	deleterious	-3,4	high_impact	4,97	neutral	0,7	damaging	0,05	deleterious	3,83	23,4	0,25	0,55	disease	0,6	disease	0,83	disease	0,69	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,49	0,73	0,9	3,31	6,87	P	0,66	P	0,8	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7182	7182	C	G	MI.4622	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1279	427	P	A	Cca/Gca	-0,8	0,02	0	probably_damaging	1	deleterious	0	neutral	2,78	neutral	-1,4	deleterious	-3,4	high_impact	3,77	neutral	0,7	damaging	0,07	deleterious	3,23	22,8	0,21	0,55	neutral	0,25	disease	0,71	disease	0,69	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	high_impact	2,38	0,77	0,9	3,31	6,87	N	0,34	N	0,76	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7182	7182	C	T	MI.4623	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1279	427	P	S	Cca/Tca	-0,8	0,02	0	probably_damaging	1	deleterious	0	neutral	2,79	neutral	-1,28	deleterious	-3,4	high_impact	4	neutral	0,7	damaging	0,06	deleterious	4,05	23,7	0,27	0,55	disease	0,6	disease	0,82	disease	0,68	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,59	0,39	0,9	3,31	6,87	N	0,31	N	0,85	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7183	7183	C	G	MI.4624	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1280	427	P	R	cCa/cGa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,66	deleterious	-3,5	deleterious	-3,84	high_impact	4,97	neutral	0,68	damaging	0,04	deleterious	3,73	23,3	0,18	0,55	disease	0,73	disease	0,92	disease	0,8	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,49	0,74	0,9	3,31	6,87	P	0,73	P	0,9	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7183	7183	C	A	MI.4625	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1280	427	P	Q	cCa/cAa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,65	deleterious	-3,86	deleterious	-3,41	high_impact	4,42	neutral	0,69	damaging	0,04	deleterious	4,22	23,9	0,16	0,55	disease	0,73	disease	0,87	disease	0,72	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,98	0,6	0,9	3,31	6,87	P	0,53	P	0,82	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7183	7183	C	T	MI.4626	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1280	427	P	L	cCa/cTa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-2,24	deleterious	-4,26	high_impact	4,17	neutral	0,71	damaging	0,03	deleterious	4,55	24,4	0,22	0,55	neutral	0,43	disease	0,87	disease	0,68	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,75	0,76	0,9	3,31	6,87	N	0,51	P	0,87	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7185	7185	C	A	MI.4627	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1282	428	Q	K	Caa/Aaa	-8,89	0	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,37	neutral	-1,68	high_impact	4,88	neutral	0,61	damaging	0,04	deleterious	4,17	23,8	0,37	0,55	neutral	0,45	disease	0,87	disease	0,76	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,41	0,63	0,9	NA	NA	P	0,7	P	0,83	polymorphism	0,95	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7185	7185	C	G	MI.4628	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1282	428	Q	E	Caa/Gaa	-8,89	0	0	probably_damaging	0,98	deleterious	0	neutral	2,72	neutral	-2,56	neutral	-1,26	high_impact	4,88	damaging	0,57	damaging	0,06	deleterious	3,28	22,8	0,36	0,55	neutral	0,49	disease	0,75	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-2,35	low_impact	-1,48	high_impact	3,41	0,61	0,9	NA	NA	P	0,63	P	0,72	polymorphism	0,97	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7186	7186	A	G	MI.4629	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1283	428	Q	R	cAa/cGa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,63	neutral	-1,68	high_impact	4,53	neutral	0,62	damaging	0,05	deleterious	3,55	23,1	0,36	0,55	disease	0,53	disease	0,88	disease	0,7	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,08	0,54	0,9	NA	NA	P	0,54	P	0,76	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8744	8744	T	A	MI.463	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	218	73	V	E	gTa/gAa	0,82	0	0	benign	0,1	neutral	0,18	neutral	4,19	deleterious	-3,54	neutral	-2,49	medium_impact	2,52	neutral	0,88	neutral	0,5	deleterious	2,84	21,6	0,16	0,65	disease	0,78	disease	0,81	disease	0,67	disease	0,79	6	neutral	0,8	deleterious	0,54	neutral	-3	neutral	0,36	medium_impact	0,15	medium_impact	-0,08	medium_impact	1,06	0,61	0,9	25,22	18,16	N	0,35	N	0,73	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7186	7186	A	C	MI.4630	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1283	428	Q	P	cAa/cCa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-3,4	deleterious	-2,51	high_impact	4,88	damaging	0,55	damaging	0,05	deleterious	3,44	23	0,19	0,55	neutral	0,3	disease	0,87	disease	0,76	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,41	0,48	0,9	NA	NA	P	0,69	P	0,84	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7186	7186	A	T	MI.4631	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1283	428	Q	L	cAa/cTa	5,68	1	0	probably_damaging	1	neutral	0,12	neutral	3,08	neutral	0,03	deleterious	-2,93	high_impact	3,77	neutral	0,65	damaging	0,05	deleterious	3,83	23,4	0,21	0,55	neutral	0,32	disease	0,85	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,79	low_impact	-3,58	medium_impact	-0,29	high_impact	2,38	0,36	0,9	NA	NA	P	0,51	P	0,71	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7187	7187	A	C	MI.4632	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1284	428	Q	H	caA/caC	8,69	1	0	probably_damaging	1	deleterious	0,02	neutral	2,72	deleterious	-3,17	neutral	-2,09	medium_impact	3,06	neutral	0,64	damaging	0,04	deleterious	3,54	23,1	0,38	0,55	disease	0,7	disease	0,79	disease	0,58	disease	0,54	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,73	0,64	0,9	NA	NA	N	0,45	N	0,7	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7187	7187	A	T	MI.4633	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1284	428	Q	H	caA/caT	8,69	1	0	probably_damaging	1	deleterious	0,02	neutral	2,72	deleterious	-3,17	neutral	-2,09	medium_impact	3,06	neutral	0,64	damaging	0,04	deleterious	3,74	23,3	0,38	0,55	disease	0,7	disease	0,79	disease	0,58	disease	0,54	1	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,73	0,64	0,9	NA	NA	N	0,46	N	0,7	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7188	7188	C	T	MI.4634	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1285	429	H	Y	Cac/Tac	1,52	1	0	probably_damaging	1	deleterious	0	neutral	2,82	neutral	-2,81	deleterious	-2,51	high_impact	5,04	neutral	0,6	damaging	0,04	deleterious	3,84	23,4	0,35	0,55	neutral	0,36	disease	0,83	disease	0,77	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,46	0,9	6,82	7,99	P	0,69	P	0,72	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7188	7188	C	A	MI.4635	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1285	429	H	N	Cac/Aac	1,52	1	0	probably_damaging	1	deleterious	0	neutral	2,75	deleterious	-3,85	deleterious	-2,93	high_impact	5,04	damaging	0,58	damaging	0,04	deleterious	4,16	23,8	0,36	0,55	disease	0,88	disease	0,8	disease	0,75	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,58	0,9	6,82	7,99	P	0,65	P	0,86	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7188	7188	C	G	MI.4636	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1285	429	H	D	Cac/Gac	1,52	1	0	probably_damaging	1	deleterious	0	neutral	2,75	deleterious	-3,95	deleterious	-3,77	high_impact	5,04	damaging	0,53	damaging	0,04	deleterious	3,97	23,6	0,25	0,55	disease	0,93	disease	0,8	disease	0,81	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,54	0,9	6,82	7,99	P	0,64	P	0,97	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7189	7189	A	G	MI.4637	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1286	429	H	R	cAc/cGc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,76	deleterious	-3,72	deleterious	-3,35	high_impact	5,04	neutral	0,62	damaging	0,04	deleterious	2,99	22,2	0,43	0,55	disease	0,89	disease	0,85	disease	0,79	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,51	0,9	6,82	7,99	P	0,75	P	0,85	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7189	7189	A	C	MI.4638	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1286	429	H	P	cAc/cCc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,75	deleterious	-4,8	deleterious	-4,19	high_impact	4,7	damaging	0,54	damaging	0,04	deleterious	3,25	22,8	0,24	0,55	disease	0,93	disease	0,84	disease	0,83	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,24	0,54	0,9	6,82	7,99	P	0,67	P	0,9	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7189	7189	A	T	MI.4639	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1286	429	H	L	cAc/cTc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,88	neutral	-2,25	deleterious	-4,6	high_impact	4	neutral	0,66	damaging	0,03	deleterious	3,78	23,4	0,22	0,55	disease	0,69	disease	0,85	disease	0,75	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,59	0,43	0,9	6,82	7,99	P	0,54	P	0,92	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8744	8744	T	G	MI.464	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	218	73	V	G	gTa/gGa	0,82	0	0	benign	0,1	neutral	0,21	neutral	4,22	neutral	-1,96	deleterious	-3,17	low_impact	1,72	neutral	0,84	neutral	0,49	deleterious	1,83	15,17	0,24	0,65	neutral	0,35	disease	0,62	disease	0,57	disease	0,72	4	neutral	0,76	deleterious	0,56	neutral	-6	neutral	0,22	medium_impact	0,15	medium_impact	-0,03	medium_impact	0,38	0,64	0,9	25,22	18,16	N	0,35	N	0,65	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7190	7190	C	G	MI.4640	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1287	429	H	Q	caC/caG	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,75	deleterious	-3,48	deleterious	-3,35	high_impact	5,04	neutral	0,64	damaging	0,04	deleterious	3,77	23,4	0,38	0,55	disease	0,88	disease	0,78	disease	0,72	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,64	0,9	6,82	7,99	P	0,73	P	0,83	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7190	7190	C	A	MI.4641	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1287	429	H	Q	caC/caA	6,84	1	0	probably_damaging	1	deleterious	0	neutral	2,75	deleterious	-3,48	deleterious	-3,35	high_impact	5,04	neutral	0,64	damaging	0,04	deleterious	4,04	23,7	0,38	0,55	disease	0,88	disease	0,78	disease	0,72	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,64	0,9	6,82	7,99	P	0,74	P	0,83	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7191	7191	T	A	MI.4642	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1288	430	F	I	Ttt/Att	-6,35	0	0	probably_damaging	1	deleterious	0	neutral	2,85	neutral	-0,55	neutral	-2,35	high_impact	4,21	neutral	0,68	neutral	0,62	deleterious	4,84	24,8	0,26	0,55	neutral	0,28	disease	0,85	disease	0,64	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	2,79	0,55	0,9	2,53	6,62	N	0,46	N	0,88	polymorphism	0,52	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7191	7191	T	C	MI.4643	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1288	430	F	L	Ttt/Ctt	-6,35	0	0	probably_damaging	0,99	deleterious	0	neutral	2,81	neutral	-0,61	neutral	-2,33	medium_impact	3,41	damaging	0,47	neutral	0,59	deleterious	4,38	24,1	0,36	0,55	neutral	0,35	disease	0,79	disease	0,55	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,74	low_impact	-2,64	low_impact	-1,48	high_impact	2,05	0,73	0,9	2,53	6,62	N	0,48	N	0,83	disease_causing	0,5	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7191	7191	T	G	MI.4644	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1288	430	F	V	Ttt/Gtt	-6,35	0	0	probably_damaging	1	deleterious	0	neutral	2,8	neutral	-0,64	deleterious	-2,74	high_impact	4,01	neutral	0,61	neutral	0,5	deleterious	4,31	24	0,31	0,55	neutral	0,17	disease	0,88	disease	0,66	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,71	low_impact	-3,58	low_impact	-1,48	high_impact	2,6	0,55	0,9	2,53	6,62	N	0,43	N	0,84	disease_causing	0,66	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7192	7192	T	C	MI.4645	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1289	430	F	S	tTt/tCt	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,66	neutral	-2,57	deleterious	-3,17	high_impact	4,21	neutral	0,74	neutral	0,63	deleterious	4,35	24,1	0,28	0,55	disease	0,55	disease	0,86	disease	0,63	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,79	0,6	0,9	2,53	6,62	P	0,56	P	0,84	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7192	7192	T	A	MI.4646	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1289	430	F	Y	tTt/tAt	5,91	1	0	probably_damaging	0,99	neutral	0,06	neutral	2,69	neutral	-1,44	neutral	-1,2	medium_impact	3,38	neutral	0,68	neutral	0,49	deleterious	4,38	24,1	0,38	0,55	neutral	0,43	disease	0,78	disease	0,57	disease	0,52	0	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,76	low_impact	-2,64	medium_impact	-0,47	high_impact	2,02	0,64	0,9	2,53	6,62	P	0,62	P	0,59	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7192	7192	T	G	MI.4647	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1289	430	F	C	tTt/tGt	5,91	1	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-3,92	deleterious	-3,18	high_impact	4,91	neutral	0,66	neutral	0,51	deleterious	4,26	23,9	0,27	0,55	disease	0,73	disease	0,88	disease	0,66	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,4	0,9	2,53	6,62	P	0,71	P	0,91	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7193	7193	T	A	MI.4648	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1290	430	F	L	ttT/ttA	5,91	1	0	probably_damaging	0,99	deleterious	0	neutral	2,81	neutral	-0,61	neutral	-2,33	medium_impact	3,41	damaging	0,47	neutral	0,59	deleterious	4,7	24,6	0,36	0,55	neutral	0,35	disease	0,79	disease	0,55	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,74	low_impact	-2,64	low_impact	-1,48	high_impact	2,05	0,73	0,9	2,53	6,62	P	0,64	P	0,83	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7193	7193	T	G	MI.4649	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1290	430	F	L	ttT/ttG	5,91	1	0	probably_damaging	0,99	deleterious	0	neutral	2,81	neutral	-0,61	neutral	-2,33	medium_impact	3,41	damaging	0,47	neutral	0,59	deleterious	4,56	24,4	0,36	0,55	neutral	0,35	disease	0,79	disease	0,55	disease	0,68	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,74	low_impact	-2,64	low_impact	-1,48	high_impact	2,05	0,73	0,9	2,53	6,62	P	0,64	P	0,83	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8746	8746	T	G	MI.465	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	220	74	S	A	Tcc/Gcc	-9,36	0	0	benign	0,16	neutral	0,11	neutral	4,34	neutral	-0,93	neutral	-2,33	low_impact	1,49	neutral	0,87	neutral	0,66	deleterious	0,57	7,93	0,34	0,65	neutral	0,4	disease	0,55	neutral	0,47	neutral	0,44	1	neutral	0,87	deleterious	0,48	neutral	-6	neutral	0,24	medium_impact	-0,07	medium_impact	-0,22	medium_impact	0,18	0,72	0,9	16,81	15,96	N	0,42	N	0,45	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7194	7194	C	G	MI.4650	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1291	431	L	V	Ctc/Gtc	-0,1	0	0	probably_damaging	0,98	deleterious	0	neutral	2,63	neutral	-1,74	neutral	-1,23	high_impact	3,9	damaging	0,45	neutral	0,44	deleterious	3,61	23,2	0,42	0,55	neutral	0,42	disease	0,71	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,35	low_impact	-1,48	high_impact	2,5	0,58	0,9	2,53	6,78	N	0,5	N	0,66	disease_causing	0,88	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7194	7194	C	T	MI.4651	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1291	431	L	F	Ctc/Ttc	-0,1	0	0	probably_damaging	1	neutral	0,07	neutral	2,52	deleterious	-3,68	neutral	-1,64	high_impact	4,1	damaging	0,36	neutral	0,37	deleterious	4,15	23,8	0,35	0,55	disease	0,68	disease	0,76	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,81	low_impact	-3,58	medium_impact	-0,43	high_impact	2,69	0,58	0,9	2,53	6,78	P	0,6	P	0,87	disease_causing	0,97	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7194	7194	C	A	MI.4652	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1291	431	L	I	Ctc/Atc	-0,1	0	0	probably_damaging	0,99	deleterious	0	neutral	2,6	neutral	-2,07	neutral	-0,82	high_impact	4,3	damaging	0,5	neutral	0,52	deleterious	4,28	24	0,33	0,55	disease	0,54	disease	0,72	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-2,64	low_impact	-1,48	high_impact	2,87	0,75	0,9	2,53	6,78	P	0,53	P	0,54	disease_causing	0,81	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7195	7195	T	G	MI.4653	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1292	431	L	R	cTc/cGc	-0,1	0,01	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-4,34	neutral	-2,47	high_impact	5	damaging	0,53	neutral	0,31	deleterious	4,3	24	0,18	0,55	disease	0,63	disease	0,9	disease	0,8	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,62	0,9	2,53	6,78	P	0,72	P	0,9	disease_causing	0,95	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7195	7195	T	C	MI.4654	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1292	431	L	P	cTc/cCc	-0,1	0,01	0	probably_damaging	1	deleterious	0	neutral	2,5	deleterious	-4,7	deleterious	-2,88	high_impact	5	damaging	0,44	neutral	0,36	deleterious	4,05	23,7	0,15	0,55	disease	0,77	disease	0,83	disease	0,79	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,61	0,9	2,53	6,78	P	0,76	P	0,83	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7195	7195	T	A	MI.4655	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1292	431	L	H	cTc/cAc	-0,1	0,01	0	probably_damaging	1	deleterious	0	neutral	2,49	deleterious	-5	deleterious	-2,88	high_impact	5	damaging	0,54	neutral	0,35	deleterious	4,19	23,9	0,19	0,55	disease	0,76	disease	0,86	disease	0,77	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,59	0,9	2,53	6,78	P	0,73	P	0,83	disease_causing	0,91	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7197	7197	G	A	MI.4656	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1294	432	G	S	Ggc/Agc	-1,95	0	0	probably_damaging	1	deleterious	0,01	neutral	-0,39	deleterious	-9,76	neutral	-2,44	high_impact	4,51	neutral	0,7	damaging	0,1	deleterious	4,36	24,1	0,23	0,55	disease	0,71	disease	0,77	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,58	medium_impact	-0,92	high_impact	3,07	0,71	0,9	2,14	6,59	N	0,42	N	0,73	polymorphism	0,61	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7197	7197	G	C	MI.4657	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1294	432	G	R	Ggc/Cgc	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	-0,4	deleterious	-11,39	deleterious	-3,27	high_impact	5,06	neutral	0,61	damaging	0,07	deleterious	4,07	23,7	0,19	0,55	disease	0,91	disease	0,86	disease	0,79	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,57	0,78	0,9	2,14	6,59	P	0,59	P	0,95	disease_causing	0,58	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7197	7197	G	T	MI.4658	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1294	432	G	C	Ggc/Tgc	-1,95	0	0	probably_damaging	1	deleterious	0	neutral	-0,4	deleterious	-12,88	deleterious	-3,68	high_impact	5,06	damaging	0,59	damaging	0,08	deleterious	4,32	24	0,16	0,55	disease	0,91	disease	0,87	disease	0,69	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,57	0,36	0,9	2,14	6,59	P	0,53	P	0,98	disease_causing	0,73	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7198	7198	G	C	MI.4659	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1295	432	G	A	gGc/gCc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	-0,37	deleterious	-8,56	neutral	-2,44	high_impact	4,71	neutral	0,79	damaging	0,13	deleterious	3,35	22,9	0,24	0,55	disease	0,66	disease	0,68	disease	0,63	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,25	0,59	0,9	2,14	6,59	P	0,64	P	0,64	disease_causing	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8746	8746	T	A	MI.466	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	220	74	S	T	Tcc/Acc	-9,36	0	0	benign	0,21	neutral	0,08	neutral	4,63	neutral	1,62	neutral	-2,13	low_impact	1,49	neutral	0,88	neutral	0,76	deleterious	0,72	8,95	0,34	0,65	neutral	0,28	disease	0,58	neutral	0,42	neutral	0,43	1	neutral	0,91	neutral	0,44	neutral	-6	neutral	0,27	medium_impact	-0,21	medium_impact	-0,31	medium_impact	0,18	0,78	0,9	16,81	15,96	N	0,43	N	0,67	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7198	7198	G	A	MI.4660	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1295	432	G	D	gGc/gAc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	-0,4	deleterious	-10,55	deleterious	-2,86	high_impact	5,06	damaging	0,59	damaging	0,08	deleterious	4,02	23,6	0,17	0,55	disease	0,9	disease	0,86	disease	0,78	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,57	0,35	0,9	2,14	6,59	P	0,67	P	0,97	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7198	7198	G	T	MI.4661	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1295	432	G	V	gGc/gTc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	-0,4	deleterious	-12,14	deleterious	-3,67	high_impact	4,51	neutral	0,61	damaging	0,09	deleterious	3,98	23,6	0,15	0,55	neutral	0,39	disease	0,86	disease	0,69	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,07	0,37	0,9	2,14	6,59	N	0,38	N	0,93	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7200	7200	C	G	MI.4662	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1297	433	L	V	Cta/Gta	-20	0	0	probably_damaging	0,99	deleterious	0,03	neutral	2,67	neutral	-1,96	neutral	-1,21	medium_impact	3,25	damaging	0,53	damaging	0,07	deleterious	3,61	23,2	0,41	0,55	neutral	0,33	disease	0,65	neutral	0,42	neutral	0,48	0	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,72	low_impact	-2,64	medium_impact	-0,65	medium_impact	1,9	0,58	0,9	3,12	6,95	N	0,3	N	0,66	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7200	7200	C	A	MI.4663	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1297	433	L	M	Cta/Ata	-20	0	0	probably_damaging	1	neutral	0,06	neutral	2,49	neutral	-2,52	neutral	-0,8	medium_impact	2,94	damaging	0,58	damaging	0,08	deleterious	3,95	23,6	0,26	0,55	disease	0,51	neutral	0,49	neutral	0,37	neutral	0,44	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,72	low_impact	-3,58	medium_impact	-0,47	medium_impact	1,62	0,69	0,9	3,12	6,95	N	0,32	N	0,59	polymorphism	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7201	7201	T	C	MI.4664	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1298	433	L	P	cTa/cCa	-0,57	0	0	probably_damaging	1	deleterious	0	neutral	2,45	deleterious	-5,24	deleterious	-2,84	high_impact	4,87	damaging	0,45	damaging	0,05	deleterious	4,13	23,8	0,2	0,55	disease	0,78	disease	0,8	disease	0,57	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,4	0,62	0,9	3,12	6,95	P	0,56	P	0,83	disease_causing	0,97	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7201	7201	T	G	MI.4665	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1298	433	L	R	cTa/cGa	-0,57	0	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-4,43	neutral	-2,43	high_impact	4,32	damaging	0,57	damaging	0,04	deleterious	4,41	24,2	0,19	0,55	disease	0,7	disease	0,88	disease	0,7	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,89	0,6	0,9	3,12	6,95	N	0,36	N	0,9	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7201	7201	T	A	MI.4666	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1298	433	L	Q	cTa/cAa	-0,57	0	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-4,82	neutral	-2,42	high_impact	4,87	damaging	0,58	damaging	0,05	deleterious	4,29	24	0,2	0,55	disease	0,72	disease	0,81	disease	0,58	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,4	0,63	0,9	3,12	6,95	P	0,62	P	0,82	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7203	7203	T	C	MI.4667	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1300	434	S	P	Tcc/Ccc	-1,95	0	0	probably_damaging	1	deleterious	0,02	neutral	2,75	neutral	-2,15	neutral	-1,18	high_impact	3,84	damaging	0,39	damaging	0,08	deleterious	4,15	23,8	0,26	0,55	disease	0,55	disease	0,87	neutral	0,47	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-3,58	medium_impact	-0,75	high_impact	2,45	0,48	0,9	9,75	9,22	N	0,44	N	0,62	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7203	7203	T	G	MI.4668	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1300	434	S	A	Tcc/Gcc	-1,95	0	0	probably_damaging	0,99	neutral	1	neutral	2,83	neutral	0,47	neutral	0,02	neutral_impact	0,02	neutral	0,73	neutral	0,91	neutral	1,16	11,51	0,31	0,55	neutral	0,17	neutral	0,13	neutral	0,12	neutral	0,25	5	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,64	low_impact	-2,64	high_impact	1,86	low_impact	-1,08	0,54	0,9	9,75	9,22	N	0,35	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7203	7203	T	A	MI.4669	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1300	434	S	T	Tcc/Acc	-1,95	0	0	probably_damaging	0,99	neutral	0,18	neutral	2,81	neutral	-0,04	neutral	-0,57	medium_impact	2,39	damaging	0,58	damaging	0,16	deleterious	3,88	23,5	0,32	0,55	neutral	0,34	disease	0,55	neutral	0,18	neutral	0,49	0	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,66	low_impact	-2,64	medium_impact	-0,17	medium_impact	1,11	0,7	0,9	9,75	9,22	N	0,49	N	0,19	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8746	8746	T	C	MI.467	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	220	74	S	P	Tcc/Ccc	-9,36	0	0	possibly_damaging	0,53	deleterious	0,02	neutral	4,26	deleterious	-4,3	deleterious	-4,26	medium_impact	2,99	neutral	0,66	neutral	0,41	deleterious	3,52	23,1	0,15	0,65	disease	0,86	disease	0,9	disease	0,75	disease	0,79	6	neutral	0,98	neutral	0,25	deleterious	4	deleterious	0,73	medium_impact	-0,81	medium_impact	-0,66	medium_impact	1,47	0,63	0,9	16,81	15,96	N	0,3	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7204	7204	C	G	MI.4670	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1301	434	S	C	tCc/tGc	1,98	0,98	0	probably_damaging	1	neutral	0,12	neutral	2,77	neutral	-1,36	neutral	-1,07	medium_impact	3,03	damaging	0,51	damaging	0,1	deleterious	3,73	23,3	0,29	0,55	disease	0,77	disease	0,8	neutral	0,49	disease	0,7	4	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,77	low_impact	-3,58	medium_impact	-0,29	medium_impact	1,7	0,52	0,9	9,75	9,22	N	0,44	N	0,41	polymorphism	0,81	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7204	7204	C	T	MI.4671	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1301	434	S	F	tCc/tTc	1,98	0,98	0	probably_damaging	1	deleterious	0,01	neutral	2,79	neutral	-0,39	neutral	-1,55	medium_impact	3,48	damaging	0,48	damaging	0,08	deleterious	4,35	24,1	0,25	0,55	disease	0,63	disease	0,81	disease	0,55	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,58	medium_impact	-0,92	high_impact	2,11	0,38	0,9	9,75	9,22	N	0,41	N	0,82	polymorphism	0,59	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7204	7204	C	A	MI.4672	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1301	434	S	Y	tCc/tAc	1,98	0,98	0	probably_damaging	1	deleterious	0,01	neutral	2,83	neutral	0,45	neutral	-1,46	medium_impact	3,14	damaging	0,52	damaging	0,09	deleterious	4,31	24	0,29	0,55	disease	0,6	disease	0,81	disease	0,54	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,8	0,63	0,9	9,75	9,22	N	0,38	N	0,91	polymorphism	0,71	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7206	7206	G	C	MI.4673	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1303	435	G	R	Gga/Cga	-10,51	0	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-4,1	deleterious	-3,22	high_impact	5,01	damaging	0,41	damaging	0,01	deleterious	4,18	23,8	0,21	0,55	disease	0,83	disease	0,84	disease	0,82	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,53	0,8	0,9	2,73	6,63	P	0,61	P	0,95	polymorphism	0,76	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7206	7206	G	T	MI.4674	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1303	435	G	W	Gga/Tga	-10,51	0	0	probably_damaging	1	deleterious	0	neutral	2,38	deleterious	-7,14	deleterious	-3,22	high_impact	4,66	damaging	0,38	damaging	0,02	deleterious	4,62	24,5	0,17	0,55	disease	0,94	disease	0,84	disease	0,76	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,2	0,36	0,9	2,73	6,63	N	0,44	N	0,83	polymorphism	0,66	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7207	7207	G	A	MI.4675	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1304	435	G	E	gGa/gAa	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,46	deleterious	-3,21	deleterious	-3,21	high_impact	4,66	damaging	0,33	damaging	0,02	deleterious	4,08	23,7	0,23	0,55	disease	0,8	disease	0,79	disease	0,81	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,2	0,62	0,9	2,73	6,63	P	0,76	P	0,93	disease_causing	1	0,47	.	.	.	.	.	.	COSM1319396	.	.	.	.	.	.	.	.
chrM	7207	7207	G	C	MI.4676	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1304	435	G	A	gGa/gCa	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,43	deleterious	-3,87	neutral	-2,4	high_impact	4,46	damaging	0,56	damaging	0,04	deleterious	3,32	22,9	0,27	0,55	disease	0,63	disease	0,69	disease	0,68	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,02	0,59	0,9	2,73	6,63	P	0,51	P	0,64	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7207	7207	G	T	MI.4677	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1304	435	G	V	gGa/gTa	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,39	deleterious	-5,45	deleterious	-3,62	high_impact	3,73	damaging	0,45	damaging	0,02	deleterious	3,94	23,5	0,15	0,55	disease	0,62	disease	0,86	disease	0,74	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,35	0,37	0,9	2,73	6,63	N	0,51	P	0,93	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7209	7209	A	G	MI.4678	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1306	436	M	V	Atg/Gtg	-11,21	0	0	probably_damaging	0,94	deleterious	0	neutral	2,64	neutral	-1,3	neutral	-1,57	high_impact	4,28	neutral	0,62	damaging	0,12	deleterious	3	22,2	0,35	0,55	disease	0,54	disease	0,73	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,75	low_impact	-1,88	low_impact	-1,48	high_impact	2,85	0,31	0,9	2,53	6,68	N	0,37	N	0,88	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7209	7209	A	C	MI.4679	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1306	436	M	L	Atg/Ctg	-11,21	0	0	probably_damaging	0,91	neutral	0,09	neutral	2,67	neutral	-1,4	neutral	-1,17	medium_impact	3,04	neutral	0,67	damaging	0,1	deleterious	3,6	23,2	0,33	0,55	neutral	0,26	disease	0,62	disease	0,6	neutral	0,47	1	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,64	low_impact	-1,7	medium_impact	-0,37	medium_impact	1,71	0,26	0,9	2,53	6,68	N	0,33	N	0,61	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8747	8747	C	T	MI.468	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	221	74	S	F	tCc/tTc	2,21	0,97	0	benign	0,22	neutral	0,07	neutral	4,36	deleterious	-4,4	deleterious	-5,13	medium_impact	3,34	neutral	0,68	neutral	0,39	deleterious	2,28	18,02	0,13	0,65	disease	0,51	disease	0,92	disease	0,66	disease	0,75	5	neutral	0,92	neutral	0,43	neutral	-3	neutral	0,36	medium_impact	-0,23	medium_impact	-0,34	medium_impact	1,77	0,46	0,9	16,81	15,96	N	0,45	N	1	disease_causing	0,96	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7209	7209	A	T	MI.4680	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1306	436	M	L	Atg/Ttg	-11,21	0	0	probably_damaging	0,91	neutral	0,09	neutral	2,67	neutral	-1,4	neutral	-1,17	medium_impact	3,04	neutral	0,67	damaging	0,1	deleterious	3,63	23,2	0,33	0,55	neutral	0,26	disease	0,62	disease	0,6	neutral	0,47	1	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,64	low_impact	-1,7	medium_impact	-0,37	medium_impact	1,71	0,26	0,9	2,53	6,68	N	0,33	N	0,61	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7210	7210	T	C	MI.4681	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1307	436	M	T	aTg/aCg	6,84	1	0	probably_damaging	0,99	deleterious	0	neutral	2,54	neutral	-2,76	neutral	-2,35	high_impact	4,62	neutral	0,7	damaging	0,13	deleterious	3,24	22,8	0,31	0,55	disease	0,71	disease	0,79	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	3,17	0,15	0,9	2,53	6,68	P	0,53	P	0,79	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7210	7210	T	A	MI.4682	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1307	436	M	K	aTg/aAg	6,84	1	0	probably_damaging	0,97	deleterious	0	neutral	2,5	deleterious	-3,67	neutral	-2,36	high_impact	4,42	neutral	0,62	damaging	0,1	deleterious	4,37	24,1	0,21	0,55	disease	0,83	disease	0,79	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-2,18	low_impact	-1,48	high_impact	2,98	0,21	0,9	2,53	6,68	P	0,55	P	0,93	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7211	7211	G	C	MI.4683	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1308	436	M	I	atG/atC	7,53	1	0	probably_damaging	0,96	deleterious	0	neutral	2,55	neutral	-1,91	neutral	-1,56	high_impact	4,28	damaging	0,57	damaging	0,15	deleterious	3,76	23,3	0,36	0,55	disease	0,53	disease	0,69	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,76	low_impact	-2,06	low_impact	-1,48	high_impact	2,85	0,33	0,9	2,53	6,68	P	0,49	N	0,87	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7211	7211	G	T	MI.4684	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1308	436	M	I	atG/atT	7,53	1	0	probably_damaging	0,96	deleterious	0	neutral	2,55	neutral	-1,91	neutral	-1,56	high_impact	4,28	damaging	0,57	damaging	0,15	deleterious	3,89	23,5	0,36	0,55	disease	0,53	disease	0,69	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,76	low_impact	-2,06	low_impact	-1,48	high_impact	2,85	0,33	0,9	2,53	6,68	P	0,5	N	0,87	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7212	7212	C	G	MI.4685	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1309	437	P	A	Ccc/Gcc	-0,33	0,28	0	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-3,21	deleterious	-3,05	high_impact	4,68	neutral	0,66	damaging	0,06	deleterious	3,3	22,9	0,36	0,55	disease	0,63	disease	0,66	disease	0,69	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,22	0,55	0,9	2,92	6,71	N	0,49	N	0,76	disease_causing	0,93	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7212	7212	C	T	MI.4686	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1309	437	P	S	Ccc/Tcc	-0,33	0,28	0	probably_damaging	1	deleterious	0	neutral	2,68	deleterious	-3,55	deleterious	-3,05	high_impact	4,68	neutral	0,65	damaging	0,03	deleterious	4,09	23,7	0,41	0,55	disease	0,67	disease	0,78	disease	0,67	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,22	0,28	0,9	2,92	6,71	N	0,49	N	0,85	disease_causing	0,96	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7212	7212	C	A	MI.4687	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1309	437	P	T	Ccc/Acc	-0,33	0,28	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	-2,69	deleterious	-3,05	high_impact	4,22	neutral	0,66	damaging	0,04	deleterious	3,88	23,5	0,36	0,55	disease	0,59	disease	0,79	disease	0,68	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,8	0,54	0,9	2,92	6,71	N	0,31	N	0,8	disease_causing	0,95	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7213	7213	C	A	MI.4688	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1310	437	P	H	cCc/cAc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,66	deleterious	-4,72	deleterious	-3,44	high_impact	5,03	neutral	0,65	damaging	0,02	deleterious	4,17	23,8	0,3	0,55	disease	0,94	disease	0,81	disease	0,77	disease	0,85	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,55	0,48	0,9	2,92	6,71	P	0,72	P	0,81	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7213	7213	C	G	MI.4689	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1310	437	P	R	cCc/cGc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-4,01	deleterious	-3,44	high_impact	4,68	neutral	0,62	damaging	0,03	deleterious	3,77	23,4	0,27	0,55	disease	0,9	disease	0,85	disease	0,78	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,22	0,37	0,9	2,92	6,71	P	0,65	P	0,9	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8747	8747	C	G	MI.469	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	221	74	S	C	tCc/tGc	2,21	0,97	0	possibly_damaging	0,78	deleterious	0	neutral	4,25	deleterious	-4,93	deleterious	-4,22	medium_impact	2,52	neutral	0,71	neutral	0,37	deleterious	3,22	22,7	0,16	0,65	disease	0,86	disease	0,86	disease	0,58	disease	0,72	4	deleterious	1	neutral	0,11	deleterious	4	deleterious	0,74	low_impact	-1,28	low_impact	-1,4	medium_impact	1,06	0,64	0,9	16,81	15,96	N	0,4	N	0,99	disease_causing	0,88	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7213	7213	C	T	MI.4690	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1310	437	P	L	cCc/cTc	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,86	neutral	-2,5	deleterious	-3,82	high_impact	4,68	neutral	0,66	damaging	0,02	deleterious	4,62	24,5	0,35	0,55	disease	0,89	disease	0,82	disease	0,66	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,22	0,84	0,9	2,92	6,71	P	0,61	P	0,87	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7215	7215	C	T	MI.4691	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1312	438	R	W	Cga/Tga	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,1	deleterious	-10,74	deleterious	-3,01	high_impact	5,05	damaging	0,5	damaging	0,03	deleterious	5,41	26	0,2	0,55	disease	0,97	disease	0,83	disease	0,77	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,83	0,9	2,34	6,74	P	0,55	P	1	polymorphism	0,71	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7215	7215	C	G	MI.4692	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1312	438	R	G	Cga/Gga	-3,57	0	0	probably_damaging	1	deleterious	0	neutral	2,11	deleterious	-8,13	deleterious	-2,63	high_impact	5,05	damaging	0,56	damaging	0,04	deleterious	4,43	24,2	0,22	0,55	disease	0,83	disease	0,72	disease	0,76	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,51	0,9	2,34	6,74	P	0,62	P	0,92	polymorphism	0,88	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7216	7216	G	C	MI.4693	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1313	438	R	P	cGa/cCa	2,9	0,98	0	probably_damaging	1	deleterious	0	neutral	2,11	deleterious	-8,81	deleterious	-2,63	high_impact	4,7	damaging	0,44	damaging	0,03	deleterious	4,45	24,2	0,19	0,55	disease	0,89	disease	0,8	disease	0,72	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,24	0,49	0,9	2,34	6,74	P	0,6	P	0,99	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7216	7216	G	A	MI.4694	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1313	438	R	Q	cGa/cAa	2,9	0,98	0	probably_damaging	1	deleterious	0	neutral	2,17	deleterious	-6,93	neutral	-1,5	high_impact	5,05	damaging	0,57	damaging	0,02	deleterious	4,7	24,6	0,26	0,55	disease	0,8	disease	0,75	disease	0,77	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,69	0,9	2,34	6,74	P	0,7	P	0,99	disease_causing	1	0,25	.	.	.	.	.	.	COSM1155671	.	.	.	.	.	.	.	.
chrM	7216	7216	G	T	MI.4695	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1313	438	R	L	cGa/cTa	2,9	0,98	0	probably_damaging	1	deleterious	0	neutral	2,18	deleterious	-8,05	deleterious	-2,63	high_impact	4,7	neutral	0,6	damaging	0,02	deleterious	4,53	24,3	0,2	0,55	disease	0,86	disease	0,88	disease	0,74	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,24	0,33	0,9	2,34	6,74	P	0,62	P	0,99	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7218	7218	C	A	MI.4696	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1315	439	R	S	Cgt/Agt	-0,33	0,41	0	probably_damaging	1	deleterious	0	neutral	2,35	deleterious	-6,75	neutral	-2,21	high_impact	4,13	neutral	0,63	neutral	0,29	deleterious	4,78	24,7	0,36	0,55	disease	0,78	disease	0,79	disease	0,75	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,71	0,57	0,9	1,36	6,8	N	0,4	N	0,8	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7218	7218	C	G	MI.4697	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1315	439	R	G	Cgt/Ggt	-0,33	0,41	0	probably_damaging	1	deleterious	0	neutral	2,33	deleterious	-6,89	deleterious	-2,59	high_impact	5,04	damaging	0,55	neutral	0,31	deleterious	4,38	24,1	0,33	0,55	disease	0,85	disease	0,72	disease	0,76	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,5	0,9	1,36	6,8	P	0,65	P	0,92	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7218	7218	C	T	MI.4698	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1315	439	R	C	Cgt/Tgt	-0,33	0,41	0	probably_damaging	1	deleterious	0	neutral	2,28	deleterious	-9,63	deleterious	-2,96	high_impact	5,04	damaging	0,54	damaging	0,15	deleterious	5,21	25,6	0,23	0,55	disease	0,96	disease	0,82	disease	0,76	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,72	0,9	1,36	6,8	P	0,62	P	1	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7219	7219	G	C	MI.4699	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1316	439	R	P	cGt/cCt	3,6	0,99	0	probably_damaging	1	deleterious	0	neutral	2,32	deleterious	-8,01	deleterious	-2,59	high_impact	4,69	damaging	0,48	damaging	0,21	deleterious	4,42	24,2	0,25	0,55	disease	0,89	disease	0,81	disease	0,75	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,23	0,54	0,9	1,36	6,8	P	0,61	P	0,99	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8546	8546	C	G	MI.47	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	20	7	A	G	gCt/gGt	-0,33	0	0	benign	0,06	neutral	0,14	neutral	4,65	neutral	-1,04	neutral	-1,29	low_impact	1,7	neutral	0,82	neutral	0,51	neutral	1,63	14	0,38	0,65	neutral	0,5	neutral	0,45	neutral	0,46	neutral	0,34	3	neutral	0,85	deleterious	0,54	neutral	-6	neutral	0,29	medium_impact	0,38	medium_impact	-0,15	medium_impact	0,36	0,8	0,9	9,29	10,06	N	0,44	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8747	8747	C	A	MI.470	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	221	74	S	Y	tCc/tAc	2,21	0,97	0	benign	0,22	deleterious	0,01	neutral	4,27	deleterious	-4,84	deleterious	-5,13	high_impact	3,8	neutral	0,72	neutral	0,37	deleterious	2,28	18,02	0,14	0,65	disease	0,82	disease	0,91	disease	0,66	disease	0,75	5	deleterious	0,99	neutral	0,4	deleterious	2	neutral	0,39	medium_impact	-0,23	medium_impact	-0,84	high_impact	2,16	0,59	0,9	16,81	15,96	N	0,43	N	1	disease_causing	0,93	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7219	7219	G	A	MI.4700	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1316	439	R	H	cGt/cAt	3,6	0,99	0	probably_damaging	1	deleterious	0	neutral	2,3	deleterious	-6,46	neutral	-1,85	high_impact	5,04	damaging	0,46	damaging	0,14	deleterious	4,61	24,4	0,36	0,55	disease	0,84	disease	0,74	disease	0,58	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,56	0,69	0,9	1,36	6,8	P	0,7	P	0,98	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7219	7219	G	T	MI.4701	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1316	439	R	L	cGt/cTt	3,6	0,99	0	probably_damaging	0,99	deleterious	0	neutral	2,3	deleterious	-7,02	deleterious	-2,59	high_impact	5,04	damaging	0,57	damaging	0,27	deleterious	4,52	24,3	0,31	0,55	disease	0,84	disease	0,88	disease	0,73	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,64	low_impact	-1,48	high_impact	3,56	0,34	0,9	1,36	6,8	P	0,71	P	0,99	disease_causing	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7221	7221	T	A	MI.4702	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1318	440	Y	N	Tac/Aac	-4,04	0	0	benign	0,4	deleterious	0	neutral	2,8	deleterious	-4,61	deleterious	-3,28	high_impact	4,88	damaging	0,55	damaging	0,12	deleterious	4,25	23,9	0,41	0,55	disease	0,76	disease	0,83	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,52	medium_impact	-0,59	low_impact	-1,48	high_impact	3,41	0,2	0,9	NA	NA	P	0,57	P	0,94	polymorphism	0,67	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7221	7221	T	C	MI.4703	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1318	440	Y	H	Tac/Cac	-4,04	0	0	possibly_damaging	0,87	deleterious	0	neutral	2,81	deleterious	-4,46	neutral	-1,82	high_impact	4,88	neutral	0,63	damaging	0,1	deleterious	3,8	23,4	0,54	0,6	disease	0,79	disease	0,72	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,72	low_impact	-1,53	low_impact	-1,48	high_impact	3,41	0,26	0,9	NA	NA	P	0,67	P	0,61	polymorphism	0,96	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7221	7221	T	G	MI.4704	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1318	440	Y	D	Tac/Gac	-4,04	0	0	benign	0,02	deleterious	0	neutral	2,81	deleterious	-4,78	deleterious	-3,65	high_impact	4,88	damaging	0,6	damaging	0,11	deleterious	4,17	23,8	0,31	0,55	disease	0,84	disease	0,84	disease	0,71	disease	0,79	6	deleterious	1	deleterious	0,49	deleterious	2	neutral	0,31	medium_impact	0,83	low_impact	-1,48	high_impact	3,41	0,28	0,9	NA	NA	P	0,58	P	0,98	polymorphism	0,74	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7222	7222	A	G	MI.4705	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1319	440	Y	C	tAc/tGc	5,68	1	0	probably_damaging	0,94	deleterious	0	neutral	2,79	deleterious	-6,1	deleterious	-3,29	high_impact	4,08	damaging	0,58	damaging	0,09	deleterious	3,77	23,4	0,43	0,55	disease	0,77	disease	0,82	disease	0,61	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,81	low_impact	-1,88	low_impact	-1,48	high_impact	2,67	0,08	0,9	NA	NA	N	0,41	N	0,89	disease_causing	1	0,34	.	.	.	.	.	muscle- pt with weakness, peripheral neuropathy, ptosis	.	.	.	.	.	.	.	.	.
chrM	7222	7222	A	T	MI.4706	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1319	440	Y	F	tAc/tTc	5,68	1	0	benign	0,43	deleterious	0,01	neutral	2,87	neutral	-2,44	neutral	-1,46	high_impact	4,88	damaging	0,51	damaging	0,12	deleterious	3,62	23,2	0,37	0,55	disease	0,59	disease	0,71	disease	0,64	disease	0,67	3	deleterious	0,99	neutral	0,29	deleterious	2	deleterious	0,52	medium_impact	-0,64	medium_impact	-0,92	high_impact	3,41	0,26	0,9	NA	NA	P	0,67	P	0,5	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7222	7222	A	C	MI.4707	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1319	440	Y	S	tAc/tCc	5,68	1	0	benign	0,4	deleterious	0	neutral	2,83	deleterious	-4,11	deleterious	-3,28	high_impact	4,88	damaging	0,58	damaging	0,18	deleterious	3,91	23,5	0,3	0,55	disease	0,61	disease	0,8	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,51	medium_impact	-0,59	low_impact	-1,48	high_impact	3,41	0,23	0,9	NA	NA	P	0,65	P	0,9	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7224	7224	T	C	MI.4708	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1321	441	S	P	Tcg/Ccg	-2,19	0	0	probably_damaging	1	neutral	0,09	neutral	2,9	neutral	-1,43	neutral	-1,76	medium_impact	2,51	damaging	0,41	damaging	0,19	deleterious	4,21	23,9	0,34	0,55	neutral	0,2	neutral	0,43	neutral	0,17	neutral	0,4	2	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,69	low_impact	-3,58	medium_impact	-0,37	medium_impact	1,22	0,61	0,9	NA	NA	P	0,55	P	0,91	disease_causing	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7224	7224	T	G	MI.4709	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1321	441	S	A	Tcg/Gcg	-2,19	0	0	probably_damaging	0,99	neutral	0,14	neutral	3,07	neutral	0,81	neutral	-1,01	medium_impact	2,02	neutral	0,6	damaging	0,2	deleterious	3,9	23,5	0,36	0,55	neutral	0,18	neutral	0,37	neutral	0,2	neutral	0,4	2	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,6	low_impact	-2,64	medium_impact	-0,25	medium_impact	0,77	0,64	0,9	NA	NA	N	0,44	N	0,35	disease_causing	0,85	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8749	8749	T	A	MI.471	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	223	75	L	M	Tta/Ata	-10,75	0	0	probably_damaging	1	neutral	0,05	neutral	3,16	deleterious	-3,88	neutral	-1,79	medium_impact	2,81	neutral	0,65	neutral	0,54	deleterious	3,52	23,1	0,28	0,65	disease	0,73	disease	0,53	disease	0,57	disease	0,52	0	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	-0,43	medium_impact	1,31	0,63	0,9	50,44	8,5	N	0,37	N	0,96	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7224	7224	T	A	MI.4710	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1321	441	S	T	Tcg/Acg	-2,19	0	0	probably_damaging	0,97	neutral	0,09	neutral	2,92	neutral	0,37	neutral	-0,97	medium_impact	2,88	damaging	0,52	damaging	0,15	deleterious	4,09	23,7	0,33	0,55	neutral	0,17	neutral	0,44	neutral	0,21	neutral	0,41	2	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,63	low_impact	-2,18	medium_impact	-0,37	medium_impact	1,56	0,81	0,9	NA	NA	N	0,47	N	0,43	disease_causing	0,95	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7225	7225	C	G	MI.4711	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1322	441	S	W	tCg/tGg	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,85	neutral	-2,49	neutral	-2,48	high_impact	4,58	damaging	0,49	damaging	0,14	deleterious	4,55	24,4	0,23	0,55	disease	0,78	disease	0,76	disease	0,59	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	3,13	0,49	0,9	NA	NA	P	0,54	P	0,94	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7225	7225	C	T	MI.4712	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1322	441	S	L	tCg/tTg	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	2,95	neutral	2,36	neutral	-2,1	high_impact	3,68	damaging	0,49	damaging	0,11	deleterious	4,82	24,8	0,28	0,55	neutral	0,29	disease	0,7	neutral	0,39	disease	0,52	0	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,69	low_impact	-3,58	medium_impact	-0,17	high_impact	2,3	0,76	0,9	NA	NA	P	0,6	P	0,9	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7227	7227	G	A	MI.4713	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1324	442	D	N	Gac/Aac	-15,6	0	0	probably_damaging	1	deleterious	0,01	neutral	2,63	neutral	0,29	neutral	-1,68	high_impact	4,17	damaging	0,43	neutral	0,37	deleterious	4,38	24,1	0,73	0,75	disease	0,68	disease	0,73	disease	0,53	disease	0,56	1	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,58	medium_impact	-0,92	high_impact	2,75	0,74	0,9	NA	NA	P	0,54	P	0,89	polymorphism	0,94	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7227	7227	G	C	MI.4714	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1324	442	D	H	Gac/Cac	-15,6	0	0	probably_damaging	1	deleterious	0,02	neutral	2,63	neutral	-0,5	neutral	-2,4	high_impact	4,07	damaging	0,5	neutral	0,29	deleterious	3,85	23,4	0,44	0,55	disease	0,85	disease	0,72	disease	0,61	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,58	medium_impact	-0,75	high_impact	2,66	0,58	0,9	NA	NA	N	0,32	N	0,97	polymorphism	0,75	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7227	7227	G	T	MI.4715	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1324	442	D	Y	Gac/Tac	-15,6	0	0	probably_damaging	1	deleterious	0	neutral	2,59	neutral	0,36	deleterious	-3,1	high_impact	4,97	damaging	0,38	neutral	0,29	deleterious	4,09	23,7	0,3	0,55	disease	0,91	disease	0,85	disease	0,67	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,49	0,32	0,9	NA	NA	P	0,65	P	0,94	polymorphism	0,58	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7228	7228	A	G	MI.4716	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1325	442	D	G	gAc/gGc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,73	neutral	0,47	neutral	-2,4	high_impact	4,97	damaging	0,45	neutral	0,43	deleterious	4,24	23,9	0,44	0,55	disease	0,77	disease	0,75	disease	0,65	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,49	0,43	0,9	NA	NA	P	0,73	P	0,85	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7228	7228	A	C	MI.4717	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1325	442	D	A	gAc/gCc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,72	neutral	2,15	deleterious	-2,76	high_impact	4,97	damaging	0,58	neutral	0,43	deleterious	3,91	23,5	0,42	0,55	disease	0,74	disease	0,74	disease	0,66	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,49	0,67	0,9	NA	NA	P	0,72	P	0,85	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7228	7228	A	T	MI.4718	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1325	442	D	V	gAc/gTc	6,14	1	0	probably_damaging	1	neutral	0,06	neutral	2,62	neutral	4,11	deleterious	-3,11	high_impact	4,28	damaging	0,45	neutral	0,34	deleterious	4,04	23,7	0,33	0,55	disease	0,88	disease	0,84	disease	0,66	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,86	low_impact	-3,58	medium_impact	-0,47	high_impact	2,85	0,33	0,9	NA	NA	P	0,63	P	0,93	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7229	7229	C	G	MI.4719	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1326	442	D	E	gaC/gaG	5,6	1	0	probably_damaging	1	deleterious	0,01	neutral	2,73	neutral	0,61	neutral	-1,38	high_impact	3,93	damaging	0,44	neutral	0,35	deleterious	4,11	23,8	0,61	0,65	neutral	0,46	disease	0,65	neutral	0,48	disease	0,51	0	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-3,58	medium_impact	-0,92	high_impact	2,53	0,61	0,9	NA	NA	P	0,7	P	0,65	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8749	8749	T	G	MI.472	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	223	75	L	V	Tta/Gta	-10,75	0	0	probably_damaging	0,99	neutral	0,06	neutral	3,29	neutral	-2,36	deleterious	-2,69	medium_impact	2,15	damaging	0,54	neutral	0,48	deleterious	3,29	22,8	0,28	0,65	disease	0,6	disease	0,54	neutral	0,48	neutral	0,47	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,77	low_impact	-2,65	medium_impact	-0,38	medium_impact	0,75	0,54	0,9	50,44	8,5	N	0,4	N	0,87	polymorphism	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7229	7229	C	A	MI.4720	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1326	442	D	E	gaC/gaA	5,6	1	0	probably_damaging	1	deleterious	0,01	neutral	2,73	neutral	0,61	neutral	-1,38	high_impact	3,93	damaging	0,44	neutral	0,35	deleterious	4,34	24,1	0,61	0,65	neutral	0,46	disease	0,65	neutral	0,48	disease	0,51	0	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-3,58	medium_impact	-0,92	high_impact	2,53	0,61	0,9	NA	NA	P	0,71	P	0,65	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7230	7230	T	C	MI.4721	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1327	443	Y	H	Tac/Cac	-0,86	0,02	0	probably_damaging	1	deleterious	0	neutral	2,39	deleterious	-3,86	neutral	-1,72	high_impact	4,24	neutral	0,62	damaging	0,05	deleterious	3,82	23,4	0,42	0,55	disease	0,79	disease	0,72	disease	0,61	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,82	0,22	0,9	2,92	6,71	N	0,34	N	0,61	disease_causing	0,87	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7230	7230	T	G	MI.4722	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1327	443	Y	D	Tac/Gac	-0,86	0,02	0	probably_damaging	1	deleterious	0	neutral	2,39	deleterious	-4,63	deleterious	-3,36	high_impact	4,93	damaging	0,52	damaging	0,05	deleterious	4,18	23,8	0,17	0,55	disease	0,76	disease	0,83	disease	0,7	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,23	0,9	2,92	6,71	P	0,62	P	0,98	disease_causing	0,98	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7230	7230	T	A	MI.4723	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1327	443	Y	N	Tac/Aac	-0,86	0,02	0	probably_damaging	1	deleterious	0	neutral	2,4	deleterious	-4,49	deleterious	-3,05	high_impact	4,58	damaging	0,53	damaging	0,06	deleterious	4,42	24,2	0,27	0,55	disease	0,75	disease	0,84	disease	0,61	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,13	0,19	0,9	2,92	6,71	N	0,4	N	0,94	disease_causing	0,99	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7231	7231	A	C	MI.4724	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1328	443	Y	S	tAc/tCc	4,67	1	0	probably_damaging	1	deleterious	0	neutral	2,42	deleterious	-3,95	deleterious	-3,01	high_impact	4,93	damaging	0,58	damaging	0,07	deleterious	4,37	24,1	0,28	0,55	neutral	0,49	disease	0,82	disease	0,67	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,18	0,9	2,92	6,71	P	0,68	P	0,9	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7231	7231	A	G	MI.4725	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1328	443	Y	C	tAc/tGc	4,67	1	0	probably_damaging	1	deleterious	0	neutral	2,38	deleterious	-5,69	deleterious	-3,01	high_impact	4,93	damaging	0,55	damaging	0,05	deleterious	4,25	23,9	0,34	0,55	disease	0,9	disease	0,83	disease	0,71	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,45	0,16	0,9	2,92	6,71	P	0,64	P	0,89	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7231	7231	A	T	MI.4726	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1328	443	Y	F	tAc/tTc	4,67	1	0	probably_damaging	0,99	neutral	0,12	neutral	2,4	neutral	-0,47	neutral	-1,15	medium_impact	2,24	damaging	0,54	damaging	0,11	deleterious	3,06	22,4	0,3	0,55	neutral	0,46	disease	0,6	neutral	0,41	neutral	0,45	1	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,78	low_impact	-2,64	medium_impact	-0,29	medium_impact	0,97	0,3	0,9	2,92	6,71	P	0,56	P	0,5	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7233	7233	C	T	MI.4727	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1330	444	P	S	Ccc/Tcc	-1,09	0	0	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-3,05	deleterious	-2,77	medium_impact	2,58	neutral	0,69	damaging	0,04	deleterious	4,05	23,7	0,34	0,55	neutral	0,36	disease	0,75	disease	0,6	disease	0,63	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	medium_impact	1,28	0,28	0,9	NA	NA	N	0,24	N	0,85	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7233	7233	C	G	MI.4728	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1330	444	P	A	Ccc/Gcc	-1,09	0	0	probably_damaging	1	deleterious	0,03	neutral	2,77	neutral	-2,44	deleterious	-2,77	medium_impact	2,61	neutral	0,68	damaging	0,06	deleterious	3,23	22,8	0,32	0,55	neutral	0,37	disease	0,61	neutral	0,38	neutral	0,44	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,73	low_impact	-3,58	medium_impact	-0,65	medium_impact	1,31	0,63	0,9	NA	NA	N	0,29	N	0,76	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7233	7233	C	A	MI.4729	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1330	444	P	T	Ccc/Acc	-1,09	0	0	probably_damaging	1	deleterious	0,01	neutral	2,72	neutral	-2,81	deleterious	-2,77	high_impact	3,52	neutral	0,7	damaging	0,04	deleterious	4,01	23,6	0,32	0,55	neutral	0,49	disease	0,78	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-3,58	medium_impact	-0,92	high_impact	2,15	0,56	0,9	NA	NA	N	0,25	N	0,8	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8750	8750	T	C	MI.473	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	224	75	L	S	tTa/tCa	-1,49	0	0	probably_damaging	1	neutral	0,05	neutral	3,1	deleterious	-6,16	deleterious	-5,38	medium_impact	3,34	neutral	0,63	neutral	0,5	deleterious	3,65	23,2	0,19	0,65	disease	0,86	disease	0,78	disease	0,63	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	-0,43	medium_impact	1,77	0,6	0,9	50,44	8,5	N	0,31	N	0,98	polymorphism	0,78	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7234	7234	C	A	MI.4730	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1331	444	P	H	cCc/cAc	7,21	1	0	probably_damaging	1	deleterious	0,03	neutral	2,69	deleterious	-4,59	deleterious	-3,12	high_impact	3,9	neutral	0,69	damaging	0,02	deleterious	4,21	23,9	0,32	0,55	disease	0,65	disease	0,76	disease	0,6	disease	0,64	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-3,58	medium_impact	-0,65	high_impact	2,5	0,49	0,9	NA	NA	N	0,44	N	0,81	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7234	7234	C	G	MI.4731	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1331	444	P	R	cCc/cGc	7,21	1	0	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-3,94	deleterious	-3,12	high_impact	4,8	neutral	0,67	damaging	0,03	deleterious	3,82	23,4	0,31	0,55	neutral	0,49	disease	0,84	disease	0,7	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,33	0,43	0,9	NA	NA	P	0,68	P	0,9	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7234	7234	C	T	MI.4732	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1331	444	P	L	cCc/cTc	7,21	1	0	probably_damaging	1	deleterious	0,03	neutral	2,8	neutral	-1,84	deleterious	-3,47	medium_impact	3,36	neutral	0,69	damaging	0,02	deleterious	4,61	24,4	0,35	0,55	neutral	0,32	disease	0,83	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,65	high_impact	2	0,65	0,9	NA	NA	N	0,46	N	0,87	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7236	7236	G	A	MI.4733	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1333	445	D	N	Gat/Aat	-0,86	0,02	0	benign	0,04	deleterious	0,01	neutral	2,74	neutral	-2,99	neutral	-1,6	high_impact	4,03	damaging	0,52	damaging	0,06	deleterious	4,38	24,1	0,51	0,6	neutral	0,42	disease	0,74	neutral	0,49	disease	0,52	0	deleterious	0,99	deleterious	0,49	deleterious	2	neutral	0,24	medium_impact	0,54	medium_impact	-0,92	high_impact	2,62	0,58	0,9	4,48	7,17	N	0,37	N	0,89	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7236	7236	G	C	MI.4734	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1333	445	D	H	Gat/Cat	-0,86	0,02	0	probably_damaging	0,94	deleterious	0	neutral	2,72	deleterious	-4,17	neutral	-2,34	high_impact	4,92	damaging	0,57	damaging	0,04	deleterious	3,92	23,5	0,33	0,55	disease	0,58	disease	0,75	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,77	low_impact	-1,88	low_impact	-1,48	high_impact	3,44	0,39	0,9	4,48	7,17	P	0,58	P	0,97	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7236	7236	G	T	MI.4735	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1333	445	D	Y	Gat/Tat	-0,86	0,02	0	probably_damaging	0,99	deleterious	0	neutral	2,75	deleterious	-4,28	deleterious	-3,05	high_impact	4,58	damaging	0,55	damaging	0,04	deleterious	4,17	23,8	0,27	0,55	disease	0,67	disease	0,86	disease	0,65	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	3,13	0,26	0,9	4,48	7,17	N	0,4	N	0,94	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7237	7237	A	C	MI.4736	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1334	445	D	A	gAt/gCt	9,29	1	0	possibly_damaging	0,57	neutral	0,06	neutral	2,8	neutral	-2,46	deleterious	-2,71	high_impact	3,95	neutral	0,63	damaging	0,07	deleterious	4,02	23,6	0,29	0,55	neutral	0,36	disease	0,75	disease	0,62	disease	0,68	4	neutral	0,94	neutral	0,25	deleterious	1	deleterious	0,57	medium_impact	-0,87	medium_impact	-0,47	high_impact	2,55	0,36	0,9	4,48	7,17	P	0,53	P	0,85	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7237	7237	A	G	MI.4737	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1334	445	D	G	gAt/gGt	9,29	1	0	possibly_damaging	0,65	deleterious	0	neutral	2,75	neutral	-1,03	neutral	-2,35	high_impact	4,58	damaging	0,58	damaging	0,05	deleterious	4,29	24	0,33	0,55	disease	0,53	disease	0,79	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	5	deleterious	0,5	low_impact	-1,01	low_impact	-1,48	high_impact	3,13	0,28	0,9	4,48	7,17	P	0,49	N	0,85	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7237	7237	A	T	MI.4738	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1334	445	D	V	gAt/gTt	9,29	1	0	probably_damaging	0,92	deleterious	0	neutral	2,78	neutral	-2,85	deleterious	-3,06	high_impact	4,38	damaging	0,56	damaging	0,05	deleterious	4,09	23,7	0,33	0,55	neutral	0,4	disease	0,85	disease	0,62	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,73	low_impact	-1,76	low_impact	-1,48	high_impact	2,95	0,2	0,9	4,48	7,17	N	0,42	N	0,93	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7238	7238	T	G	MI.4739	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1335	445	D	E	gaT/gaG	6,98	1	0	benign	0,22	deleterious	0,03	neutral	2,78	neutral	-2,27	neutral	-1,34	medium_impact	3,38	damaging	0,49	damaging	0,05	deleterious	4,08	23,7	0,4	0,55	neutral	0,24	disease	0,65	neutral	0,3	neutral	0,44	1	neutral	0,97	neutral	0,41	deleterious	1	neutral	0,27	medium_impact	-0,24	medium_impact	-0,65	high_impact	2,02	0,38	0,9	4,48	7,17	P	0,53	P	0,65	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8750	8750	T	G	MI.474	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	224	75	L	W	tTa/tGa	-1,49	0	0	probably_damaging	1	deleterious	0	neutral	3,09	deleterious	-7,41	deleterious	-5,46	high_impact	4,38	damaging	0,55	neutral	0,4	deleterious	3,64	23,2	0,11	0,65	disease	0,96	disease	0,79	disease	0,68	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,6	low_impact	-1,4	high_impact	2,66	0,48	0,9	50,44	8,5	N	0,36	N	1	polymorphism	0,69	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7238	7238	T	A	MI.4740	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1335	445	D	E	gaT/gaA	6,98	1	0	benign	0,22	deleterious	0,03	neutral	2,78	neutral	-2,27	neutral	-1,34	medium_impact	3,38	damaging	0,49	damaging	0,05	deleterious	4,22	23,9	0,4	0,55	neutral	0,24	disease	0,65	neutral	0,3	neutral	0,44	1	neutral	0,97	neutral	0,41	deleterious	1	neutral	0,27	medium_impact	-0,24	medium_impact	-0,65	high_impact	2,02	0,38	0,9	4,48	7,17	P	0,53	P	0,65	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7239	7239	G	C	MI.4741	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1336	446	A	P	Gca/Cca	-4,09	0	0	probably_damaging	1	deleterious	0,01	neutral	2,71	neutral	-1,9	neutral	-1,31	high_impact	3,62	damaging	0,45	damaging	0,06	deleterious	4,03	23,6	0,14	0,55	disease	0,7	disease	0,74	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,58	medium_impact	-0,92	high_impact	2,24	0,8	0,9	NA	NA	N	0,32	N	0,85	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7239	7239	G	A	MI.4742	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1336	446	A	T	Gca/Aca	-4,09	0	0	probably_damaging	1	neutral	0,16	neutral	2,75	neutral	-0,39	neutral	-0,81	medium_impact	1,96	damaging	0,51	damaging	0,06	deleterious	3,31	22,9	0,43	0,55	neutral	0,49	neutral	0,49	neutral	0,23	neutral	0,47	1	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,72	low_impact	-3,58	medium_impact	-0,21	medium_impact	0,71	0,64	0,9	NA	NA	N	0,36	N	0,2	disease_causing	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7239	7239	G	T	MI.4743	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1336	446	A	S	Gca/Tca	-4,09	0	0	probably_damaging	1	neutral	0,24	neutral	2,77	neutral	-0,51	neutral	-0,43	neutral_impact	0,6	damaging	0,52	damaging	0,08	deleterious	2,44	19,08	0,39	0,55	neutral	0,44	neutral	0,19	neutral	0,18	neutral	0,36	3	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,72	low_impact	-3,58	medium_impact	-0,09	medium_impact	-0,55	0,77	0,9	NA	NA	N	0,46	N	0,64	disease_causing	0,98	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7240	7240	C	T	MI.4744	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1337	446	A	V	gCa/gTa	6,06	1	0	probably_damaging	1	neutral	0,16	neutral	2,78	neutral	1	neutral	-1,04	medium_impact	2,19	damaging	0,5	damaging	0,08	deleterious	3,45	23	0,29	0,55	neutral	0,41	neutral	0,47	neutral	0,24	neutral	0,48	0	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,72	low_impact	-3,58	medium_impact	-0,21	medium_impact	0,92	0,65	0,9	NA	NA	P	0,61	P	0,75	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7240	7240	C	A	MI.4745	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1337	446	A	E	gCa/gAa	6,06	1	0	probably_damaging	1	neutral	0,06	neutral	2,79	neutral	-1,22	neutral	-1,2	medium_impact	2,58	damaging	0,5	damaging	0,07	deleterious	4,63	24,5	0,15	0,55	neutral	0,26	disease	0,7	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,74	low_impact	-3,58	medium_impact	-0,47	medium_impact	1,28	0,58	0,9	NA	NA	P	0,52	P	0,76	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7240	7240	C	G	MI.4746	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1337	446	A	G	gCa/gGa	6,06	1	0	probably_damaging	0,99	neutral	0,08	neutral	2,75	neutral	-1,4	neutral	-1	low_impact	1,52	damaging	0,53	damaging	0,09	deleterious	4,12	23,8	0,3	0,55	neutral	0,29	neutral	0,47	neutral	0,37	neutral	0,47	1	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,69	low_impact	-2,64	medium_impact	-0,4	medium_impact	0,3	0,73	0,9	NA	NA	P	0,55	P	0,56	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7242	7242	T	C	MI.4747	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1339	447	Y	H	Tac/Cac	-5,47	0	0	probably_damaging	1	deleterious	0	neutral	2,71	neutral	-0,95	neutral	-1,56	high_impact	3,95	neutral	0,61	damaging	0,05	deleterious	3,78	23,4	0,34	0,55	disease	0,69	disease	0,71	disease	0,73	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,55	0,43	0,9	1,75	6,73	N	0,3	N	0,61	polymorphism	0,92	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7242	7242	T	A	MI.4748	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1339	447	Y	N	Tac/Aac	-5,47	0	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-0,48	deleterious	-2,6	high_impact	3,95	damaging	0,55	damaging	0,06	deleterious	4,23	23,9	0,28	0,55	disease	0,77	disease	0,84	disease	0,67	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,55	0,2	0,9	1,75	6,73	N	0,24	N	0,94	polymorphism	0,52	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7242	7242	T	G	MI.4749	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1339	447	Y	D	Tac/Gac	-5,47	0	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-0,91	deleterious	-2,8	high_impact	4,29	damaging	0,52	damaging	0,05	deleterious	4,2	23,9	0,19	0,55	disease	0,85	disease	0,85	disease	0,74	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,86	0,36	0,9	1,75	6,73	N	0,33	N	0,98	polymorphism	0,6	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8751	8751	A	T	MI.475	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	225	75	L	F	ttA/ttT	5,68	0,9	0	probably_damaging	1	deleterious	0,01	neutral	3,16	deleterious	-3,94	deleterious	-3,61	medium_impact	3,23	damaging	0,55	neutral	0,4	deleterious	3,5	23,1	0,3	0,65	disease	0,84	disease	0,72	disease	0,65	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,67	0,58	0,9	50,44	8,5	N	0,48	N	0,97	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7243	7243	A	T	MI.4750	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1340	447	Y	F	tAc/tTc	5,83	1	0	probably_damaging	1	neutral	0,25	neutral	2,86	neutral	1,2	neutral	-0,26	neutral_impact	0,11	damaging	0,51	damaging	0,15	deleterious	1,91	15,63	0,4	0,55	neutral	0,17	neutral	0,17	neutral	0,24	neutral	0,25	5	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,69	low_impact	-3,58	medium_impact	-0,07	medium_impact	-1	0,45	0,9	1,75	6,73	P	0,64	P	0,5	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7243	7243	A	C	MI.4751	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1340	447	Y	S	tAc/tCc	5,83	1	0	probably_damaging	1	deleterious	0	neutral	2,73	neutral	0,68	neutral	-2,44	high_impact	3,95	damaging	0,59	damaging	0,07	deleterious	3,85	23,4	0,27	0,55	disease	0,69	disease	0,82	disease	0,66	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,55	0,25	0,9	1,75	6,73	N	0,44	N	0,9	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7243	7243	A	G	MI.4752	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1340	447	Y	C	tAc/tGc	5,83	1	0	probably_damaging	1	deleterious	0	neutral	2,7	neutral	-0,97	neutral	-2,44	high_impact	4,29	damaging	0,55	damaging	0,05	deleterious	3,63	23,2	0,32	0,55	disease	0,85	disease	0,85	disease	0,69	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,86	0,15	0,9	1,75	6,73	N	0,45	N	0,89	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7245	7245	A	G	MI.4753	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1342	448	T	A	Acc/Gcc	-3,86	0	0	probably_damaging	0,97	neutral	0,35	neutral	2,85	neutral	0,28	neutral	-0,82	low_impact	1,43	neutral	0,68	neutral	0,65	deleterious	2,33	18,34	0,62	0,65	neutral	0,28	neutral	0,15	neutral	0,16	neutral	0,28	4	neutral	0,97	neutral	0,19	neutral	-2	deleterious	0,64	low_impact	-2,18	medium_impact	0,04	medium_impact	0,22	0,48	0,9	2,34	7,44	N	0,51	P	0,69	polymorphism	0,52	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7245	7245	A	T	MI.4754	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1342	448	T	S	Acc/Tcc	-3,86	0	0	probably_damaging	0,97	neutral	0,53	neutral	2,8	neutral	-0,32	neutral	-0,74	low_impact	1	neutral	0,65	neutral	0,68	deleterious	2,07	16,68	0,45	0,55	neutral	0,36	neutral	0,28	neutral	0,16	neutral	0,46	1	neutral	0,97	neutral	0,28	neutral	-2	deleterious	0,68	low_impact	-2,18	medium_impact	0,22	medium_impact	-0,18	0,71	0,9	2,34	7,44	N	0,43	N	0,79	polymorphism	0,76	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7245	7245	A	C	MI.4755	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1342	448	T	P	Acc/Ccc	-3,86	0	0	probably_damaging	1	deleterious	0,03	neutral	2,71	neutral	-2,02	neutral	-1,35	high_impact	3,86	damaging	0,56	neutral	0,42	deleterious	3,6	23,2	0,17	0,55	disease	0,66	disease	0,7	neutral	0,48	disease	0,51	0	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-3,58	medium_impact	-0,65	high_impact	2,47	0,66	0,9	2,34	7,44	N	0,39	N	0,92	disease_causing	0,82	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7246	7246	C	G	MI.4756	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1343	448	T	S	aCc/aGc	3,75	0,98	0	probably_damaging	0,97	neutral	0,53	neutral	2,8	neutral	-0,32	neutral	-0,74	low_impact	1	neutral	0,65	neutral	0,68	deleterious	2,37	18,65	0,45	0,55	neutral	0,36	neutral	0,28	neutral	0,16	neutral	0,46	1	neutral	0,97	neutral	0,28	neutral	-2	deleterious	0,68	low_impact	-2,18	medium_impact	0,22	medium_impact	-0,18	0,71	0,9	2,34	7,44	P	0,49	N	0,79	disease_causing	0,91	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7246	7246	C	T	MI.4757	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1343	448	T	I	aCc/aTc	3,75	0,98	0	probably_damaging	1	neutral	0,08	neutral	2,75	neutral	3,5	neutral	-0,79	low_impact	1,68	neutral	0,61	neutral	0,62	deleterious	3,08	22,5	0,42	0,55	neutral	0,47	neutral	0,41	neutral	0,2	neutral	0,47	1	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,73	low_impact	-3,58	medium_impact	-0,4	medium_impact	0,45	0,7	0,9	2,34	7,44	P	0,6	P	0,92	disease_causing	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7246	7246	C	A	MI.4758	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1343	448	T	N	aCc/aAc	3,75	0,98	0	probably_damaging	1	deleterious	0,04	neutral	2,77	neutral	-1,52	neutral	-1,14	medium_impact	2,88	neutral	0,63	neutral	0,53	deleterious	3,85	23,4	0,53	0,6	neutral	0,43	disease	0,6	neutral	0,31	disease	0,53	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,74	low_impact	-3,58	medium_impact	-0,58	medium_impact	1,56	0,77	0,9	2,34	7,44	P	0,54	P	0,8	disease_causing	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7248	7248	A	T	MI.4759	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1345	449	T	S	Aca/Tca	-6,63	0	0	benign	0,18	neutral	0,34	neutral	2,77	neutral	2,51	neutral	-0,02	neutral_impact	-0,08	neutral	0,7	neutral	0,74	neutral	-0,37	0,46	0,4	0,55	neutral	0,32	neutral	0,08	neutral	0,17	neutral	0,29	4	neutral	0,6	deleterious	0,58	neutral	-6	neutral	0,19	medium_impact	-0,14	medium_impact	0,03	low_impact	-1,17	0,72	0,9	7,99	16,77	P	0,58	P	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8751	8751	A	C	MI.476	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	225	75	L	F	ttA/ttC	5,68	0,9	0	probably_damaging	1	deleterious	0,01	neutral	3,16	deleterious	-3,94	deleterious	-3,61	medium_impact	3,23	damaging	0,55	neutral	0,4	deleterious	3,36	22,9	0,3	0,65	disease	0,84	disease	0,72	disease	0,65	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,67	0,58	0,9	50,44	8,5	N	0,47	N	0,97	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7248	7248	A	C	MI.4760	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1345	449	T	P	Aca/Cca	-6,63	0	0	possibly_damaging	0,54	neutral	0,08	neutral	3	neutral	-2,15	neutral	-0,82	low_impact	1,64	damaging	0,55	neutral	0,4	deleterious	0,68	8,71	0,18	0,55	disease	0,61	disease	0,54	neutral	0,49	neutral	0,49	0	neutral	0,92	neutral	0,27	neutral	-3	deleterious	0,47	medium_impact	-0,82	medium_impact	-0,4	medium_impact	0,42	0,7	0,9	7,99	16,77	N	0,4	N	0,76	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7248	7248	A	G	MI.4761	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1345	449	T	A	Aca/Gca	-6,63	0	0	benign	0,01	neutral	0,23	neutral	2,83	neutral	0,2	neutral	-0,26	low_impact	1,5	neutral	0,76	neutral	0,96	neutral	-0,22	0,99	0,5	0,55	neutral	0,16	neutral	0,15	neutral	0,31	neutral	0,28	4	neutral	0,76	deleterious	0,61	neutral	-6	neutral	0,09	medium_impact	1,12	medium_impact	-0,1	medium_impact	0,29	0,5	0,9	7,99	16,77	N	0,47	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7249	7249	C	A	MI.4762	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1346	449	T	K	aCa/aAa	-0,17	0	0	benign	0,26	neutral	0,25	neutral	2,75	neutral	1,76	neutral	-0,43	medium_impact	1,96	neutral	0,66	neutral	0,63	neutral	1,16	11,52	0,26	0,55	neutral	0,41	neutral	0,24	neutral	0,47	neutral	0,43	1	neutral	0,7	deleterious	0,5	neutral	-3	neutral	0,34	medium_impact	-0,33	medium_impact	-0,07	medium_impact	0,71	0,65	0,9	7,99	16,77	N	0,47	N	0,69	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7249	7249	C	T	MI.4763	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1346	449	T	M	aCa/aTa	-0,17	0	0	benign	0,05	neutral	0,25	neutral	2,77	neutral	-1,3	neutral	-0,16	neutral_impact	0,78	neutral	0,76	neutral	0,97	deleterious	0,8	9,49	0,34	0,55	neutral	0,37	neutral	0,13	neutral	0,22	neutral	0,31	4	neutral	0,73	deleterious	0,6	neutral	-6	neutral	0,13	medium_impact	0,45	medium_impact	-0,07	medium_impact	-0,38	0,66	0,9	7,99	16,77	N	0,52	P	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7251	7251	T	C	MI.4764	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1348	450	W	R	Tga/Cga	-2,71	0	0	probably_damaging	1	deleterious	0	neutral	2,64	deleterious	-5,28	deleterious	-4,84	high_impact	4,86	damaging	0,49	damaging	0,19	deleterious	3,73	23,3	0,22	0,55	disease	0,63	disease	0,88	disease	0,85	disease	0,86	7	deleterious	1	deleterious	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	3,39	0,4	0,9	3,12	6,92	P	0,66	P	0,98	polymorphism	0,99	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7251	7251	T	G	MI.4765	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1348	450	W	G	Tga/Gga	-2,71	0	0	probably_damaging	1	deleterious	0	neutral	2,65	deleterious	-4,67	deleterious	-4,49	high_impact	4,86	damaging	0,57	neutral	0,35	deleterious	4,12	23,8	0,19	0,55	neutral	0,48	disease	0,83	disease	0,82	disease	0,82	6	deleterious	1	deleterious	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,39	0,32	0,9	3,12	6,92	P	0,66	P	0,89	polymorphism	0,98	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7252	7252	G	C	MI.4766	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1349	450	W	S	tGa/tCa	5,83	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-4,98	deleterious	-4,84	high_impact	4,51	neutral	0,65	neutral	0,33	deleterious	4,2	23,9	0,17	0,55	disease	0,52	disease	0,9	disease	0,8	disease	0,82	6	deleterious	1	deleterious	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,07	0,3	0,9	3,12	6,92	P	0,51	P	0,89	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7252	7252	G	T	MI.4767	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1349	450	W	L	tGa/tTa	5,83	1	0	probably_damaging	1	deleterious	0	neutral	2,83	deleterious	-4,37	deleterious	-4,5	medium_impact	2,73	damaging	0,58	neutral	0,32	deleterious	4,41	24,1	0,21	0,55	neutral	0,16	disease	0,83	disease	0,78	disease	0,78	6	deleterious	1	deleterious	0	deleterious	5	deleterious	0,74	low_impact	-3,58	low_impact	-1,48	medium_impact	1,42	0,36	0,9	3,12	6,92	N	0,43	N	0,95	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7253	7253	A	C	MI.4768	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1350	450	W	C	tgA/tgC	9,29	1	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-6,86	deleterious	-4,5	high_impact	4,86	damaging	0,56	damaging	0,2	deleterious	4,19	23,8	0,21	0,55	disease	0,73	disease	0,89	disease	0,83	disease	0,85	7	deleterious	1	deleterious	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,39	0,28	0,9	3,12	6,92	P	0,68	P	0,88	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7253	7253	A	T	MI.4769	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1350	450	W	C	tgA/tgT	9,29	1	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-6,86	deleterious	-4,5	high_impact	4,86	damaging	0,56	damaging	0,2	deleterious	4,32	24	0,21	0,55	disease	0,73	disease	0,89	disease	0,83	disease	0,85	7	deleterious	1	deleterious	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,39	0,28	0,9	3,12	6,92	P	0,69	P	0,88	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8752	8752	A	C	MI.477	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	226	76	I	L	Atc/Ctc	-1,95	0	0	probably_damaging	0,93	neutral	0,19	neutral	4,66	neutral	1,66	neutral	-0,53	neutral_impact	-0,16	neutral	0,92	neutral	0,81	deleterious	2,47	19,24	0,22	0,65	neutral	0,36	neutral	0,41	neutral	0,25	neutral	0,45	1	neutral	0,96	neutral	0,13	neutral	-2	deleterious	0,62	low_impact	-1,82	medium_impact	-0,06	low_impact	-1,24	0,47	0,9	18,58	16,92	N	0,43	N	0,83	polymorphism	0,5	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7254	7254	A	C	MI.4770	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1351	451	N	H	Aac/Cac	8,59	1	0	probably_damaging	1	deleterious	0,03	neutral	2,77	deleterious	-4,61	neutral	-1,73	medium_impact	2,66	damaging	0,54	damaging	0,06	deleterious	3,29	22,8	0,35	0,55	neutral	0,43	disease	0,72	disease	0,64	disease	0,52	0	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-3,58	medium_impact	-0,65	medium_impact	1,36	0,68	0,9	2,34	6,89	N	0,42	N	0,83	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7254	7254	A	T	MI.4771	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1351	451	N	Y	Aac/Tac	8,59	1	0	probably_damaging	1	deleterious	0	neutral	2,87	deleterious	-5,08	deleterious	-2,76	high_impact	4,62	damaging	0,53	damaging	0,05	deleterious	3,93	23,5	0,21	0,55	disease	0,83	disease	0,85	disease	0,76	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,17	0,64	0,9	2,34	6,89	P	0,55	P	0,93	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7254	7254	A	G	MI.4772	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1351	451	N	D	Aac/Gac	8,59	1	0	probably_damaging	0,99	deleterious	0	neutral	2,76	neutral	-2,69	neutral	-1,73	high_impact	4,96	damaging	0,44	damaging	0,06	deleterious	4,05	23,7	0,49	0,55	disease	0,57	disease	0,73	disease	0,81	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,79	low_impact	-2,64	low_impact	-1,48	high_impact	3,48	0,79	0,9	2,34	6,89	P	0,78	P	0,92	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7255	7255	A	G	MI.4773	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1352	451	N	S	aAc/aGc	8,59	1	0	probably_damaging	0,98	neutral	0,07	neutral	2,76	deleterious	-3,03	neutral	-1,72	high_impact	4,16	damaging	0,54	damaging	0,07	deleterious	3,15	22,6	0,5	0,6	disease	0,55	disease	0,77	disease	0,74	disease	0,76	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,82	low_impact	-2,35	medium_impact	-0,43	high_impact	2,74	0,54	0,9	2,34	6,89	P	0,56	P	0,79	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7255	7255	A	T	MI.4774	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1352	451	N	I	aAc/aTc	8,59	1	0	probably_damaging	1	deleterious	0	neutral	2,79	deleterious	-4,69	deleterious	-3,11	high_impact	4,96	damaging	0,57	damaging	0,06	deleterious	3,96	23,6	0,21	0,55	disease	0,79	disease	0,88	disease	0,74	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,48	0,57	0,9	2,34	6,89	P	0,73	P	0,98	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7255	7255	A	C	MI.4775	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1352	451	N	T	aAc/aCc	8,59	1	0	probably_damaging	1	deleterious	0	neutral	2,77	deleterious	-3,52	neutral	-2,07	high_impact	4,62	damaging	0,57	damaging	0,07	deleterious	3,51	23,1	0,35	0,55	disease	0,61	disease	0,79	disease	0,75	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,17	0,75	0,9	2,34	6,89	P	0,56	P	0,59	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7256	7256	C	A	MI.4776	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1353	451	N	K	aaC/aaA	8,59	1	0,01	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-2,7	neutral	-2,07	high_impact	4,26	damaging	0,51	damaging	0,04	deleterious	4,63	24,5	0,42	0,55	neutral	0,28	disease	0,77	disease	0,81	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,83	0,73	0,9	2,34	6,89	P	0,56	P	0,92	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7256	7256	C	G	MI.4777	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1353	451	N	K	aaC/aaG	8,59	1	0,01	probably_damaging	1	deleterious	0	neutral	2,76	neutral	-2,7	neutral	-2,07	high_impact	4,26	damaging	0,51	damaging	0,04	deleterious	4,13	23,8	0,42	0,55	neutral	0,28	disease	0,77	disease	0,81	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,58	low_impact	-1,48	high_impact	2,83	0,73	0,9	2,34	6,89	P	0,56	P	0,92	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7257	7257	A	T	MI.4778	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1354	452	I	F	Atc/Ttc	-6,63	0	0	benign	0,22	neutral	0,12	neutral	2,73	neutral	-1,33	neutral	-1,02	low_impact	1,09	neutral	0,66	neutral	0,68	deleterious	2,25	17,81	0,47	0,55	neutral	0,22	disease	0,54	neutral	0,21	neutral	0,42	2	neutral	0,86	neutral	0,45	neutral	-6	neutral	0,23	medium_impact	-0,24	medium_impact	-0,29	medium_impact	-0,09	0,83	0,9	15,2	52,77	N	0,52	P	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7257	7257	A	G	MI.4779	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1354	452	I	V	Atc/Gtc	-6,63	0	0	benign	0	neutral	0,81	neutral	2,82	neutral	-0,11	neutral	-0,02	neutral_impact	-0,22	neutral	0,8	neutral	0,99	neutral	-1,29	0,01	0,6	0,65	neutral	0,16	neutral	0,09	neutral	0,18	neutral	0,27	5	neutral	0,18	deleterious	0,91	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,54	low_impact	-1,3	0,72	0,9	15,2	52,77	N	0,41	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8752	8752	A	T	MI.478	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	226	76	I	F	Atc/Ttc	-1,95	0	0	probably_damaging	0,99	neutral	1	neutral	5,08	neutral	2,92	neutral	-2,17	neutral_impact	-1,18	neutral	0,92	neutral	0,9	deleterious	2,5	19,44	0,23	0,65	disease	0,51	neutral	0,33	neutral	0,36	neutral	0,34	3	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,68	low_impact	-2,65	high_impact	1,98	low_impact	-2,11	0,6	0,9	18,58	16,92	N	0,27	N	0,97	disease_causing	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7257	7257	A	C	MI.4780	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1354	452	I	L	Atc/Ctc	-6,63	0	0	benign	0,01	neutral	0,39	neutral	2,91	neutral	-0,17	neutral	-0,38	neutral_impact	0,3	neutral	0,71	neutral	0,8	deleterious	0,38	6,41	0,37	0,55	neutral	0,17	neutral	0,26	neutral	0,16	neutral	0,43	1	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,08	medium_impact	1,12	medium_impact	0,09	medium_impact	-0,82	0,75	0,9	15,2	52,77	N	0,54	P	0,14	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7258	7258	T	A	MI.4781	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1355	452	I	N	aTc/aAc	0,75	0	0,01	benign	0,14	deleterious	0,02	neutral	2,68	neutral	2,81	neutral	-1,52	medium_impact	2,4	neutral	0,64	neutral	0,48	deleterious	2,95	22,1	0,32	0,55	neutral	0,47	disease	0,66	neutral	0,36	disease	0,51	0	neutral	0,98	neutral	0,44	deleterious	1	neutral	0,27	medium_impact	-0,01	medium_impact	-0,75	medium_impact	1,12	0,74	0,9	15,2	52,77	N	0,42	N	0,17	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7258	7258	T	C	MI.4782	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1355	452	I	T	aTc/aCc	0,75	0	0,01	benign	0	neutral	1	neutral	2,73	neutral	-0,01	neutral	-0,78	neutral_impact	0,46	neutral	0,75	neutral	0,97	neutral	-0,45	0,29	0,41	0,55	neutral	0,16	neutral	0,27	neutral	0,24	neutral	0,42	2	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,07	high_impact	1,86	medium_impact	-0,67	0,72	0,9	15,2	52,77	N	0,38	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7258	7258	T	G	MI.4783	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1355	452	I	S	aTc/aGc	0,75	0	0,01	benign	0	neutral	0,26	neutral	2,72	neutral	0,36	neutral	-1,23	neutral_impact	0,72	neutral	0,71	neutral	0,83	neutral	1,29	12,21	0,31	0,55	neutral	0,23	disease	0,54	neutral	0,26	neutral	0,43	1	neutral	0,74	deleterious	0,63	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	-0,06	medium_impact	-0,43	0,69	0,9	15,2	52,77	N	0,47	N	0,09	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7259	7259	C	A	MI.4784	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1356	452	I	M	atC/atA	1,68	0	0	benign	0,02	neutral	0,19	neutral	2,75	neutral	-1,59	neutral	-0,44	neutral_impact	0,12	neutral	0,74	neutral	0,93	deleterious	2,22	17,63	0,54	0,6	neutral	0,25	neutral	0,13	neutral	0,18	neutral	0,29	4	neutral	0,8	deleterious	0,59	neutral	-6	neutral	0,09	medium_impact	0,83	medium_impact	-0,16	medium_impact	-0,99	0,84	0,9	15,2	52,77	P	0,6	P	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7259	7259	C	G	MI.4785	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1356	452	I	M	atC/atG	1,68	0	0	benign	0,02	neutral	0,19	neutral	2,75	neutral	-1,59	neutral	-0,44	neutral_impact	0,12	neutral	0,74	neutral	0,93	neutral	1,74	14,65	0,54	0,6	neutral	0,25	neutral	0,13	neutral	0,18	neutral	0,29	4	neutral	0,8	deleterious	0,59	neutral	-6	neutral	0,09	medium_impact	0,83	medium_impact	-0,16	medium_impact	-0,99	0,84	0,9	15,2	52,77	P	0,59	P	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7260	7260	C	A	MI.4786	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1357	453	L	M	Cta/Ata	-13,08	0	0	benign	0,02	neutral	0,12	neutral	2,59	neutral	-1,38	neutral	-0,23	neutral_impact	0,78	neutral	0,76	neutral	0,86	deleterious	2,34	18,4	0,34	0,55	neutral	0,4	neutral	0,25	neutral	0,29	neutral	0,46	1	neutral	0,88	deleterious	0,55	neutral	-6	neutral	0,12	medium_impact	0,83	medium_impact	-0,29	medium_impact	-0,38	0,73	0,9	14,23	34,92	N	0,48	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7260	7260	C	G	MI.4787	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1357	453	L	V	Cta/Gta	-13,08	0	0	benign	0	neutral	1	neutral	2,69	neutral	-0,29	neutral	0,35	neutral_impact	-0,7	neutral	0,84	neutral	0,99	neutral	-0,84	0,03	0,34	0,55	neutral	0,2	neutral	0,08	neutral	0,22	neutral	0,25	5	neutral	0	deleterious	1	neutral	-6	neutral	0,08	high_impact	2,07	high_impact	1,86	low_impact	-1,75	0,72	0,9	14,23	34,92	N	0,36	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7261	7261	T	C	MI.4788	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1358	453	L	P	cTa/cCa	-2,48	0	0	benign	0,35	deleterious	0	neutral	2,5	neutral	0,34	neutral	-1,6	medium_impact	3,1	damaging	0,56	neutral	0,44	deleterious	4	23,6	0,09	0,55	disease	0,81	disease	0,83	disease	0,64	disease	0,82	6	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,58	medium_impact	-0,5	low_impact	-1,48	medium_impact	1,76	0,57	0,9	14,23	34,92	N	0,29	N	0,73	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7261	7261	T	A	MI.4789	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1358	453	L	Q	cTa/cAa	-2,48	0	0	possibly_damaging	0,46	deleterious	0	neutral	2,5	neutral	-0,18	neutral	-1,54	medium_impact	3,1	neutral	0,68	neutral	0,6	deleterious	4,2	23,9	0,11	0,55	disease	0,78	disease	0,59	neutral	0,49	disease	0,54	1	deleterious	1	neutral	0,27	deleterious	4	deleterious	0,46	medium_impact	-0,69	low_impact	-1,48	medium_impact	1,76	0,66	0,9	14,23	34,92	N	0,37	N	0,55	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8752	8752	A	G	MI.479	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	226	76	I	V	Atc/Gtc	-1,95	0	0	probably_damaging	0,93	deleterious	0,02	neutral	4,32	neutral	-1,01	neutral	-0,48	low_impact	1,59	neutral	0,93	neutral	0,6	deleterious	1,82	15,12	0,36	0,65	neutral	0,49	neutral	0,28	neutral	0,34	neutral	0,4	2	deleterious	0,99	neutral	0,05	deleterious	2	deleterious	0,63	low_impact	-1,82	medium_impact	-0,66	medium_impact	0,27	0,32	0,9	18,58	16,92	N	0,47	N	0,77	polymorphism	0,7	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7261	7261	T	G	MI.4790	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1358	453	L	R	cTa/cGa	-2,48	0	0	benign	0,35	deleterious	0	neutral	2,5	neutral	-2,44	neutral	-1,64	medium_impact	3,1	neutral	0,63	neutral	0,5	deleterious	4,28	24	0,08	0,55	disease	0,77	disease	0,81	disease	0,64	disease	0,79	6	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,5	medium_impact	-0,5	low_impact	-1,48	medium_impact	1,76	0,69	0,9	14,23	34,92	N	0,31	N	0,66	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7263	7263	T	A	MI.4791	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1360	454	S	T	Tca/Aca	-20	0	0	probably_damaging	0,97	deleterious	0	neutral	2,77	deleterious	-3,75	neutral	-1,03	high_impact	3,94	damaging	0,5	damaging	0,16	deleterious	3,89	23,5	0,22	0,55	disease	0,5	disease	0,64	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-2,18	low_impact	-1,48	high_impact	2,54	0,73	0,9	1,56	6,65	N	0,4	N	0,43	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7263	7263	T	G	MI.4792	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1360	454	S	A	Tca/Gca	-20	0	0	probably_damaging	0,99	neutral	0,06	neutral	2,87	neutral	-2,98	neutral	-1,03	medium_impact	2,8	damaging	0,6	damaging	0,18	deleterious	3,87	23,5	0,28	0,55	neutral	0,28	neutral	0,46	neutral	0,47	neutral	0,4	2	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,67	low_impact	-2,64	medium_impact	-0,47	medium_impact	1,49	0,74	0,9	1,56	6,65	N	0,38	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7263	7263	T	C	MI.4793	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1360	454	S	P	Tca/Cca	-20	0	0	probably_damaging	1	deleterious	0	neutral	2,73	deleterious	-5,11	neutral	-1,72	high_impact	3,77	damaging	0,38	damaging	0,21	deleterious	4,14	23,8	0,14	0,55	disease	0,71	disease	0,82	disease	0,73	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,38	0,77	0,9	1,56	6,65	N	0,44	N	0,91	polymorphism	0,96	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7264	7264	C	T	MI.4794	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1361	454	S	L	tCa/tTa	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,82	deleterious	-4,68	neutral	-2,06	high_impact	4,57	damaging	0,5	damaging	0,13	deleterious	4,78	24,7	0,12	0,55	disease	0,57	disease	0,85	disease	0,63	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,12	0,8	0,9	1,56	6,65	P	0,54	P	0,9	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7264	7264	C	G	MI.4795	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1361	454	S	W	tCa/tGa	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,72	deleterious	-7,75	neutral	-2,41	high_impact	4,92	damaging	0,49	damaging	0,15	deleterious	4,47	24,2	0,1	0,55	disease	0,91	disease	0,88	disease	0,71	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,44	0,49	0,9	1,56	6,65	P	0,69	P	0,94	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7266	7266	T	G	MI.4796	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1363	455	S	A	Tct/Gct	-7,55	0	0	probably_damaging	0,98	deleterious	0	neutral	2,71	neutral	-2,73	neutral	-0,9	high_impact	4,86	neutral	0,6	damaging	0,19	deleterious	3,89	23,5	0,31	0,55	neutral	0,36	disease	0,57	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,71	low_impact	-2,35	low_impact	-1,48	high_impact	3,39	0,72	0,9	2,73	7,32	P	0,65	P	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7266	7266	T	C	MI.4797	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1363	455	S	P	Tct/Cct	-7,55	0	0	probably_damaging	1	deleterious	0	neutral	2,6	deleterious	-4,87	neutral	-1,53	high_impact	4,51	damaging	0,49	damaging	0,15	deleterious	4,11	23,8	0,18	0,55	disease	0,77	disease	0,83	disease	0,8	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,07	0,72	0,9	2,73	7,32	N	0,51	P	0,91	polymorphism	0,98	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7266	7266	T	A	MI.4798	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1363	455	S	T	Tct/Act	-7,55	0	0	probably_damaging	0,97	neutral	0,14	neutral	2,85	deleterious	-3,12	neutral	-0,59	low_impact	1,86	damaging	0,52	damaging	0,26	deleterious	2,85	21,6	0,24	0,55	neutral	0,24	neutral	0,49	neutral	0,47	neutral	0,42	2	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,65	low_impact	-2,18	medium_impact	-0,25	medium_impact	0,62	0,79	0,9	2,73	7,32	N	0,41	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7267	7267	C	A	MI.4799	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1364	455	S	Y	tCt/tAt	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-4,24	neutral	-1,87	high_impact	4,86	damaging	0,55	damaging	0,13	deleterious	4,24	23,9	0,16	0,55	neutral	0,32	disease	0,86	disease	0,71	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	3,39	0,7	0,9	2,73	7,32	P	0,65	P	0,92	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8546	8546	C	A	MI.48	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	20	7	A	D	gCt/gAt	-0,33	0	0	benign	0,19	neutral	0,85	neutral	4,73	neutral	-0,32	neutral	0,33	neutral_impact	-0,82	neutral	0,73	neutral	0,71	deleterious	2,46	19,23	0,31	0,65	neutral	0,34	neutral	0,12	neutral	0,27	neutral	0,22	6	neutral	0,09	deleterious	0,83	neutral	-6	neutral	0,36	medium_impact	-0,16	medium_impact	0,72	low_impact	-1,8	0,54	0,9	9,29	10,06	N	0,31	N	0,96	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8753	8753	T	G	MI.480	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	227	76	I	S	aTc/aGc	4,76	0,99	0	probably_damaging	0,99	neutral	0,05	neutral	4,26	deleterious	-3,57	deleterious	-3,6	low_impact	1,8	neutral	0,84	neutral	0,42	deleterious	4,17	23,8	0,22	0,65	disease	0,78	disease	0,69	disease	0,51	disease	0,59	2	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,77	low_impact	-2,65	medium_impact	-0,43	medium_impact	0,45	0,49	0,9	18,58	16,92	N	0,48	N	0,98	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7267	7267	C	T	MI.4800	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1364	455	S	F	tCt/tTt	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,67	deleterious	-3,81	neutral	-1,87	high_impact	4,51	damaging	0,44	damaging	0,08	deleterious	4,25	23,9	0,14	0,55	disease	0,77	disease	0,9	disease	0,71	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,07	0,48	0,9	2,73	7,32	P	0,62	P	0,98	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7267	7267	C	G	MI.4801	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1364	455	S	C	tCt/tGt	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,6	neutral	-0,92	neutral	-1,53	high_impact	4,51	damaging	0,55	damaging	0,12	deleterious	3,7	23,3	0,21	0,55	disease	0,83	disease	0,82	disease	0,67	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	3,07	0,61	0,9	2,73	7,32	P	0,48	N	0,85	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7269	7269	G	C	MI.4802	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1366	456	V	L	Gta/Cta	-20	0	0	benign	0,02	neutral	0,38	neutral	2,83	neutral	2,66	neutral	0,05	neutral_impact	-1,09	neutral	0,73	neutral	0,81	neutral	-0,21	1,04	0,52	0,6	neutral	0,27	neutral	0,24	neutral	0,22	neutral	0,43	1	neutral	0,6	deleterious	0,68	neutral	-6	neutral	0,16	medium_impact	0,83	medium_impact	0,07	low_impact	-2,11	0,85	0,9	15,01	35,33	N	0,49	N	0,06	polymorphism	1	0,01	rs386829004	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7269	7269	G	A	MI.4803	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1366	456	V	M	Gta/Ata	-20	0	0	benign	0,02	neutral	0,31	neutral	2,6	neutral	0,41	neutral	-0,17	neutral_impact	0,03	neutral	0,77	neutral	0,95	deleterious	0,31	5,84	0,48	0,55	neutral	0,37	neutral	0,18	neutral	0,22	neutral	0,35	3	neutral	0,68	deleterious	0,65	neutral	-6	neutral	0,15	medium_impact	0,83	medium_impact	0	low_impact	-1,07	0,87	0,9	15,01	35,33	N	0,44	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7269	7269	G	T	MI.4804	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1366	456	V	L	Gta/Tta	-20	0	0	benign	0,02	neutral	0,38	neutral	2,83	neutral	2,66	neutral	0,05	neutral_impact	-1,09	neutral	0,73	neutral	0,81	neutral	-0,1	1,71	0,52	0,6	neutral	0,27	neutral	0,24	neutral	0,22	neutral	0,43	1	neutral	0,6	deleterious	0,68	neutral	-6	neutral	0,16	medium_impact	0,83	medium_impact	0,07	low_impact	-2,11	0,85	0,9	15,01	35,33	N	0,49	N	0,06	polymorphism	1	0,01	rs386829004	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7270	7270	T	A	MI.4805	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1367	456	V	E	gTa/gAa	1,21	0,31	0,02	benign	0,38	deleterious	0	neutral	2,56	neutral	-2,89	neutral	-1,61	medium_impact	2,71	neutral	0,64	neutral	0,52	deleterious	3	22,2	0,15	0,55	disease	0,7	disease	0,79	disease	0,64	disease	0,78	6	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,44	medium_impact	-0,56	low_impact	-1,48	medium_impact	1,4	0,59	0,9	15,01	35,33	N	0,29	N	0,24	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7270	7270	T	G	MI.4806	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1367	456	V	G	gTa/gGa	1,21	0,31	0,02	benign	0,2	deleterious	0,02	neutral	2,62	deleterious	-3,32	neutral	-1,92	medium_impact	2,71	neutral	0,68	neutral	0,55	deleterious	2,2	17,51	0,22	0,55	disease	0,67	disease	0,57	disease	0,51	disease	0,57	1	neutral	0,98	neutral	0,41	deleterious	1	neutral	0,35	medium_impact	-0,19	medium_impact	-0,75	medium_impact	1,4	0,63	0,9	15,01	35,33	N	0,35	N	0,23	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7270	7270	T	C	MI.4807	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1367	456	V	A	gTa/gCa	1,21	0,31	0,02	benign	0,13	deleterious	0	neutral	2,66	neutral	-1,52	neutral	-1	low_impact	1,32	neutral	0,71	neutral	0,91	neutral	1,79	14,92	0,41	0,55	neutral	0,41	neutral	0,31	neutral	0,48	neutral	0,47	1	deleterious	1	neutral	0,44	neutral	-2	neutral	0,22	medium_impact	0,02	low_impact	-1,48	medium_impact	0,12	0,52	0,9	15,01	35,33	N	0,42	N	0	polymorphism	1	0,03	rs879002867	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7272	7272	G	T	MI.4808	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1369	457	G	C	Ggc/Tgc	-2,48	0	0	probably_damaging	1	deleterious	0	neutral	1,87	deleterious	-7,42	deleterious	-3,07	high_impact	5	damaging	0,39	damaging	0,02	deleterious	4,25	23,9	0,14	0,55	disease	0,9	disease	0,88	disease	0,7	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,57	0,9	3,31	6,61	P	0,52	P	0,98	polymorphism	0,82	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7272	7272	G	C	MI.4809	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1369	457	G	R	Ggc/Cgc	-2,48	0	0	probably_damaging	1	deleterious	0	neutral	1,87	deleterious	-6,4	deleterious	-2,73	high_impact	4,66	damaging	0,44	damaging	0,02	deleterious	4,06	23,7	0,11	0,55	disease	0,92	disease	0,86	disease	0,8	disease	0,88	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,58	low_impact	-1,48	high_impact	3,2	0,62	0,9	3,31	6,61	P	0,54	P	0,95	polymorphism	0,9	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8753	8753	T	C	MI.481	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	227	76	I	T	aTc/aCc	4,76	0,99	0	probably_damaging	0,99	deleterious	0	neutral	4,27	neutral	-2,85	deleterious	-2,94	low_impact	0,98	neutral	0,92	neutral	0,74	deleterious	3,33	22,9	0,3	0,65	disease	0,72	neutral	0,38	neutral	0,45	disease	0,65	3	deleterious	1	neutral	0,01	deleterious	2	deleterious	0,73	low_impact	-2,65	low_impact	-1,4	medium_impact	-0,26	0,56	0,9	18,58	16,92	P	0,53	P	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7272	7272	G	A	MI.4810	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1369	457	G	S	Ggc/Agc	-2,48	0	0	probably_damaging	1	deleterious	0	neutral	1,96	deleterious	-5,1	neutral	-2,05	high_impact	3,68	damaging	0,47	damaging	0,03	deleterious	4,34	24	0,16	0,55	disease	0,6	disease	0,81	disease	0,62	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,58	low_impact	-1,48	high_impact	2,3	0,51	0,9	3,31	6,61	N	0,3	N	0,73	polymorphism	0,95	0,14	rs28415137	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7273	7273	G	T	MI.4811	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1370	457	G	V	gGc/gTc	9,29	1	0	probably_damaging	1	deleterious	0	neutral	1,89	deleterious	-6,19	deleterious	-3,07	high_impact	4,3	damaging	0,48	damaging	0,03	deleterious	3,91	23,5	0,14	0,55	disease	0,85	disease	0,85	disease	0,69	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,87	0,48	0,9	3,31	6,61	N	0,48	N	0,93	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7273	7273	G	C	MI.4812	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1370	457	G	A	gGc/gCc	9,29	1	0	probably_damaging	1	deleterious	0	neutral	2,04	deleterious	-4,83	neutral	-2,05	high_impact	4,03	damaging	0,58	damaging	0,04	deleterious	3,27	22,8	0,18	0,55	neutral	0,35	disease	0,66	disease	0,62	disease	0,67	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,62	0,64	0,9	3,31	6,61	N	0,44	N	0,64	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7273	7273	G	A	MI.4813	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1370	457	G	D	gGc/gAc	9,29	1	0	probably_damaging	1	deleterious	0	neutral	1,88	deleterious	-5,9	neutral	-2,39	high_impact	5	damaging	0,29	damaging	0,02	deleterious	4,02	23,6	0,13	0,55	disease	0,9	disease	0,86	disease	0,77	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,52	0,48	0,9	3,31	6,61	P	0,82	P	0,97	disease_causing	1	0,49	.	.	.	.	.	.	COSM1319394	.	.	.	.	.	.	.	.
chrM	7275	7275	T	G	MI.4814	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1372	458	S	A	Tca/Gca	-9,62	0	0	probably_damaging	0,98	deleterious	0,02	neutral	2,94	neutral	-2,98	neutral	-0,94	medium_impact	2,31	damaging	0,56	neutral	0,29	deleterious	1,9	15,6	0,41	0,55	neutral	0,19	disease	0,52	neutral	0,36	neutral	0,42	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,65	low_impact	-2,35	medium_impact	-0,75	medium_impact	1,03	0,79	0,9	1,95	6,79	N	0,39	N	0,35	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7275	7275	T	A	MI.4815	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1372	458	S	T	Tca/Aca	-9,62	0	0	probably_damaging	0,97	deleterious	0	neutral	2,76	deleterious	-3,75	neutral	-0,99	high_impact	3,83	damaging	0,46	damaging	0,06	deleterious	2,13	17,06	0,32	0,55	disease	0,55	disease	0,64	neutral	0,49	neutral	0,47	1	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,77	low_impact	-2,18	low_impact	-1,48	high_impact	2,44	0,84	0,9	1,95	6,79	N	0,37	N	0,43	polymorphism	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7275	7275	T	C	MI.4816	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1372	458	S	P	Tca/Cca	-9,62	0	0	probably_damaging	1	deleterious	0	neutral	2,73	deleterious	-5,11	neutral	-1,66	high_impact	4,32	damaging	0,24	damaging	0,06	deleterious	3,86	23,5	0,16	0,55	disease	0,75	disease	0,85	disease	0,7	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	2,89	0,75	0,9	1,95	6,79	P	0,66	P	0,91	disease_causing_automatic	0,12	0,18	rs267606884	Pathogenic	Familial_colorectal_cancer	RCV000010311.4	MedGen	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	7276	7276	C	G	MI.4817	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1373	458	S	W	tCa/tGa	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,7	deleterious	-7,75	neutral	-2,34	high_impact	4,87	damaging	0,42	damaging	0,04	deleterious	4,49	24,3	0,13	0,55	disease	0,94	disease	0,9	disease	0,63	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,58	low_impact	-1,48	high_impact	3,4	0,49	0,9	1,95	6,79	P	0,65	P	0,94	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7276	7276	C	T	MI.4818	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1373	458	S	L	tCa/tTa	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,71	deleterious	-4,68	neutral	-1,99	high_impact	4,17	damaging	0,5	damaging	0,03	deleterious	4,44	24,2	0,18	0,55	disease	0,7	disease	0,87	disease	0,55	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,75	0,9	0,95	1,95	6,79	P	0,5	N	0,9	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7278	7278	T	A	MI.4819	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1375	459	F	I	Ttc/Atc	-8,7	0	0	benign	0,11	neutral	0,28	neutral	2,75	neutral	2,29	neutral	0,3	neutral_impact	-0,12	neutral	0,73	neutral	0,7	neutral	1,27	12,12	0,27	0,55	neutral	0,31	neutral	0,38	neutral	0,22	neutral	0,44	1	neutral	0,68	deleterious	0,59	neutral	-6	neutral	0,26	medium_impact	0,1	medium_impact	-0,04	low_impact	-1,21	0,75	0,9	3,9	9,36	N	0,43	N	0,88	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8753	8753	T	A	MI.482	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	227	76	I	N	aTc/aAc	4,76	0,99	0	probably_damaging	1	deleterious	0	neutral	4,26	deleterious	-4,66	deleterious	-4,54	medium_impact	2,14	neutral	0,85	neutral	0,39	deleterious	4,47	24,2	0,2	0,65	disease	0,88	disease	0,75	disease	0,54	disease	0,75	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,82	low_impact	-3,6	low_impact	-1,4	medium_impact	0,74	0,62	0,9	18,58	16,92	N	0,46	N	1	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7278	7278	T	C	MI.4820	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1375	459	F	L	Ttc/Ctc	-8,7	0	0	benign	0	neutral	1	neutral	2,83	neutral	2,5	neutral	0,4	neutral_impact	-0,44	neutral	0,71	neutral	0,72	neutral	-0,19	1,16	0,42	0,55	neutral	0,23	neutral	0,22	neutral	0,18	neutral	0,41	2	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,07	high_impact	1,86	low_impact	-1,51	0,77	0,9	3,9	9,36	N	0,42	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7278	7278	T	G	MI.4821	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1375	459	F	V	Ttc/Gtc	-8,7	0	0	benign	0,32	neutral	0,07	neutral	2,85	neutral	1,83	neutral	0,2	low_impact	0,92	neutral	0,69	neutral	0,58	deleterious	2,81	21,4	0,33	0,55	neutral	0,21	disease	0,51	neutral	0,28	neutral	0,43	1	neutral	0,92	neutral	0,38	neutral	-6	neutral	0,27	medium_impact	-0,45	medium_impact	-0,43	medium_impact	-0,25	0,79	0,9	3,9	9,36	N	0,49	N	0,84	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7279	7279	T	A	MI.4822	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1376	459	F	Y	tTc/tAc	0,06	0,04	0	benign	0,37	neutral	0,11	neutral	2,65	neutral	-1,03	neutral	-0,08	neutral_impact	0,43	neutral	0,67	neutral	0,64	neutral	0,93	10,27	0,45	0,55	neutral	0,47	neutral	0,26	neutral	0,24	neutral	0,42	2	neutral	0,87	neutral	0,37	neutral	-6	deleterious	0,44	medium_impact	-0,54	medium_impact	-0,31	medium_impact	-0,7	0,74	0,9	3,9	9,36	N	0,51	P	0,59	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7279	7279	T	C	MI.4823	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1376	459	F	S	tTc/tCc	0,06	0,04	0	possibly_damaging	0,78	neutral	0,07	neutral	2,73	neutral	-0,35	neutral	-0,4	medium_impact	2,74	neutral	0,62	neutral	0,64	deleterious	3,02	22,3	0,33	0,55	neutral	0,43	neutral	0,49	neutral	0,43	neutral	0,47	1	neutral	0,95	neutral	0,15	NA	0	deleterious	0,62	low_impact	-1,27	medium_impact	-0,43	medium_impact	1,43	0,65	0,9	3,9	9,36	P	0,51	P	0,84	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7279	7279	T	G	MI.4824	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1376	459	F	C	tTc/tGc	0,06	0,04	0	probably_damaging	0,94	deleterious	0,01	neutral	2,63	neutral	-1,69	neutral	-0,45	medium_impact	2,4	damaging	0,59	neutral	0,44	deleterious	4,21	23,9	0,25	0,55	disease	0,69	disease	0,69	neutral	0,43	neutral	0,5	0	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,75	low_impact	-1,88	medium_impact	-0,92	medium_impact	1,12	0,5	0,9	3,9	9,36	N	0,4	N	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7280	7280	C	A	MI.4825	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1377	459	F	L	ttC/ttA	5,6	0,87	0,01	benign	0	neutral	1	neutral	2,83	neutral	2,5	neutral	0,4	neutral_impact	-0,44	neutral	0,71	neutral	0,72	deleterious	0,43	6,86	0,42	0,55	neutral	0,23	neutral	0,22	neutral	0,18	neutral	0,41	2	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,07	high_impact	1,86	low_impact	-1,51	0,77	0,9	3,9	9,36	N	0,46	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7280	7280	C	G	MI.4826	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1377	459	F	L	ttC/ttG	5,6	0,87	0,01	benign	0	neutral	1	neutral	2,83	neutral	2,5	neutral	0,4	neutral_impact	-0,44	neutral	0,71	neutral	0,72	deleterious	0,09	3,51	0,42	0,55	neutral	0,23	neutral	0,22	neutral	0,18	neutral	0,41	2	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,07	high_impact	1,86	low_impact	-1,51	0,77	0,9	3,9	9,36	N	0,46	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7281	7281	A	C	MI.4827	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1378	460	I	L	Att/Ctt	-5,01	0	0	benign	0,06	neutral	0,12	neutral	2,91	neutral	-0,33	neutral	-0,48	low_impact	1,24	neutral	0,66	damaging	0,17	deleterious	0,87	9,89	0,3	0,55	neutral	0,21	disease	0,51	neutral	0,29	neutral	0,42	2	neutral	0,87	deleterious	0,53	neutral	-6	neutral	0,16	medium_impact	0,37	medium_impact	-0,29	medium_impact	0,05	0,68	0,9	6,63	13,2	N	0,42	N	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7281	7281	A	T	MI.4828	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1378	460	I	F	Att/Ttt	-5,01	0	0	possibly_damaging	0,55	deleterious	0,03	neutral	2,58	neutral	-2,9	neutral	-1,15	medium_impact	3,06	neutral	0,61	damaging	0,09	deleterious	2,29	18,09	0,3	0,55	disease	0,52	disease	0,78	neutral	0,49	disease	0,59	2	neutral	0,97	neutral	0,24	deleterious	4	deleterious	0,64	medium_impact	-0,84	medium_impact	-0,65	medium_impact	1,73	0,72	0,9	6,63	13,2	N	0,26	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7281	7281	A	G	MI.4829	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1378	460	I	V	Att/Gtt	-5,01	0	0	benign	0,06	neutral	0,15	neutral	2,72	neutral	-1,38	neutral	-0,27	low_impact	1,82	neutral	0,65	neutral	0,41	deleterious	0,22	4,87	0,51	0,6	neutral	0,36	neutral	0,34	neutral	0,35	neutral	0,43	1	neutral	0,84	deleterious	0,55	neutral	-6	neutral	0,17	medium_impact	0,37	medium_impact	-0,23	medium_impact	0,58	0,62	0,9	6,63	13,2	N	0,47	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8754	8754	C	A	MI.483	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	228	76	I	M	atC/atA	3,14	0,99	0	probably_damaging	1	neutral	0,53	neutral	4,35	neutral	-0,48	neutral	-0,07	neutral_impact	-1,35	neutral	0,81	neutral	0,74	neutral	1,05	10,94	0,3	0,65	disease	0,52	neutral	0,08	neutral	0,22	neutral	0,25	5	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,32	low_impact	-2,25	0,56	0,9	18,58	16,92	N	0,37	N	0,75	disease_causing	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7282	7282	T	G	MI.4830	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1379	460	I	S	aTt/aGt	3,98	0,99	0	probably_damaging	0,95	deleterious	0	neutral	2,53	deleterious	-4,53	neutral	-1,77	high_impact	4,21	neutral	0,66	damaging	0,15	deleterious	4,32	24	0,26	0,55	disease	0,68	disease	0,84	disease	0,55	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,78	low_impact	-1,96	low_impact	-1,48	high_impact	2,79	0,59	0,9	6,63	13,2	N	0,44	N	0,65	disease_causing	0,62	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7282	7282	T	A	MI.4831	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1379	460	I	N	aTt/aAt	3,98	0,99	0	probably_damaging	0,99	deleterious	0	neutral	2,52	deleterious	-5,65	neutral	-2,11	high_impact	4,21	neutral	0,63	damaging	0,11	deleterious	4,51	24,3	0,23	0,55	disease	0,82	disease	0,78	disease	0,57	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,64	low_impact	-1,48	high_impact	2,79	0,7	0,9	6,63	13,2	N	0,44	N	0,95	disease_causing	0,56	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7282	7282	T	C	MI.4832	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1379	460	I	T	aTt/aCt	3,98	0,99	0	probably_damaging	0,95	deleterious	0	neutral	2,54	deleterious	-4	neutral	-1,46	high_impact	3,86	neutral	0,66	damaging	0,14	deleterious	3,36	22,9	0,31	0,55	disease	0,62	disease	0,66	disease	0,55	disease	0,58	2	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,69	low_impact	-1,96	low_impact	-1,48	high_impact	2,47	0,66	0,9	6,63	13,2	N	0,45	N	0,79	polymorphism	0,71	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7283	7283	T	G	MI.4833	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1380	460	I	M	atT/atG	5,83	1	0	benign	0,06	neutral	0,11	neutral	2,61	neutral	-2,44	neutral	-0,66	low_impact	1,82	neutral	0,66	damaging	0,26	deleterious	0,53	7,66	0,36	0,55	neutral	0,4	neutral	0,48	neutral	0,31	neutral	0,46	1	neutral	0,88	deleterious	0,53	neutral	-6	neutral	0,18	medium_impact	0,37	medium_impact	-0,31	medium_impact	0,58	0,78	0,9	6,63	13,2	P	0,59	P	0,73	disease_causing	0,58	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7283	7283	T	A	MI.4834	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1380	460	I	M	atT/atA	5,83	1	0	benign	0,06	neutral	0,11	neutral	2,61	neutral	-2,44	neutral	-0,66	low_impact	1,82	neutral	0,66	damaging	0,26	deleterious	0,74	9,11	0,36	0,55	neutral	0,4	neutral	0,48	neutral	0,31	neutral	0,46	1	neutral	0,88	deleterious	0,53	neutral	-6	neutral	0,18	medium_impact	0,37	medium_impact	-0,31	medium_impact	0,58	0,78	0,9	6,63	13,2	P	0,6	P	0,73	disease_causing	0,58	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7284	7284	T	C	MI.4835	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1381	461	S	P	Tct/Cct	-8,01	0	0	probably_damaging	0,99	deleterious	0	neutral	2,8	neutral	-1,82	neutral	-1,64	high_impact	4,75	damaging	0,41	neutral	0,48	deleterious	4,1	23,7	0,17	0,55	disease	0,66	disease	0,85	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,64	low_impact	-1,48	high_impact	3,29	0,73	0,9	NA	NA	P	0,78	P	0,91	polymorphism	0,96	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7284	7284	T	G	MI.4836	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1381	461	S	A	Tct/Gct	-8,01	0	0	probably_damaging	0,97	deleterious	0,01	neutral	2,91	neutral	0,41	neutral	-0,98	high_impact	3,64	damaging	0,59	neutral	0,5	deleterious	3,86	23,5	0,38	0,55	neutral	0,32	disease	0,56	disease	0,54	neutral	0,46	1	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,69	low_impact	-2,18	medium_impact	-0,92	high_impact	2,26	0,75	0,9	NA	NA	N	0,45	N	0,33	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7284	7284	T	A	MI.4837	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1381	461	S	T	Tct/Act	-8,01	0	0	probably_damaging	0,95	neutral	0,06	neutral	2,86	neutral	2,48	neutral	-0,9	medium_impact	2,44	damaging	0,5	neutral	0,46	deleterious	3,92	23,5	0,29	0,55	neutral	0,25	disease	0,54	neutral	0,39	neutral	0,44	1	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,72	low_impact	-1,96	medium_impact	-0,47	medium_impact	1,15	0,86	0,9	NA	NA	N	0,5	N	0,42	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7285	7285	C	T	MI.4838	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1382	461	S	F	tCt/tTt	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,92	neutral	-1,71	neutral	-1,97	high_impact	3,6	damaging	0,39	neutral	0,38	deleterious	4,33	24	0,17	0,55	neutral	0,45	disease	0,89	disease	0,63	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,23	0,61	0,9	NA	NA	P	0,73	P	0,98	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7285	7285	C	A	MI.4839	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1382	461	S	Y	tCt/tAt	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,86	neutral	-2,11	neutral	-1,97	high_impact	4,75	damaging	0,43	neutral	0,39	deleterious	4,16	23,8	0,18	0,55	disease	0,52	disease	0,86	disease	0,65	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,81	0,9	NA	NA	P	0,8	P	0,92	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8754	8754	C	G	MI.484	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	228	76	I	M	atC/atG	3,14	0,99	0	probably_damaging	1	neutral	0,53	neutral	4,35	neutral	-0,48	neutral	-0,07	neutral_impact	-1,35	neutral	0,81	neutral	0,74	deleterious	0,55	7,79	0,3	0,65	disease	0,52	neutral	0,08	neutral	0,22	neutral	0,25	5	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,32	low_impact	-2,25	0,56	0,9	18,58	16,92	N	0,37	N	0,75	disease_causing	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7285	7285	C	G	MI.4840	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1382	461	S	C	tCt/tGt	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,79	neutral	-2,4	neutral	-1,64	high_impact	4,75	damaging	0,48	neutral	0,41	deleterious	3,75	23,3	0,24	0,55	disease	0,64	disease	0,81	disease	0,61	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,58	low_impact	-1,48	high_impact	3,29	0,75	0,9	NA	NA	P	0,7	P	0,84	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7287	7287	C	A	MI.4841	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1384	462	L	M	Cta/Ata	-7,09	0	0	benign	0,05	neutral	0,29	neutral	2,76	neutral	-1,84	neutral	-0,1	low_impact	1,15	neutral	0,7	neutral	0,31	deleterious	0,41	6,73	0,33	0,55	neutral	0,46	neutral	0,26	neutral	0,23	neutral	0,46	1	neutral	0,69	deleterious	0,62	neutral	-6	neutral	0,14	medium_impact	0,45	medium_impact	-0,02	medium_impact	-0,04	0,74	0,9	3,12	8,28	N	0,45	N	0,55	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7287	7287	C	G	MI.4842	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1384	462	L	V	Cta/Gta	-7,09	0	0	benign	0,08	neutral	0,23	neutral	2,87	neutral	0,14	neutral	-0,43	medium_impact	2,92	neutral	0,61	damaging	0,14	deleterious	0,3	5,67	0,4	0,55	neutral	0,27	neutral	0,4	neutral	0,23	neutral	0,45	1	neutral	0,74	deleterious	0,58	neutral	-3	neutral	0,14	medium_impact	0,24	medium_impact	-0,1	medium_impact	1,6	0,7	0,9	3,12	8,28	N	0,48	N	0,64	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7288	7288	T	A	MI.4843	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1385	462	L	Q	cTa/cAa	-0,17	0	0	probably_damaging	0,96	deleterious	0	neutral	2,74	deleterious	-3,79	neutral	-1,22	medium_impact	3,46	neutral	0,63	damaging	0,11	deleterious	4,07	23,7	0,21	0,55	disease	0,61	disease	0,68	neutral	0,44	neutral	0,5	0	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,74	low_impact	-2,06	low_impact	-1,48	high_impact	2,1	0,7	0,9	3,12	8,28	N	0,32	N	0,84	polymorphism	0,71	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7288	7288	T	G	MI.4844	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1385	462	L	R	cTa/cGa	-0,17	0	0	probably_damaging	0,96	deleterious	0	neutral	2,75	deleterious	-3,63	neutral	-1,29	medium_impact	3,46	damaging	0,58	damaging	0,09	deleterious	4,18	23,8	0,19	0,55	disease	0,59	disease	0,87	disease	0,59	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,82	low_impact	-2,06	low_impact	-1,48	high_impact	2,1	0,71	0,9	3,12	8,28	N	0,27	N	0,88	polymorphism	0,67	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7288	7288	T	C	MI.4845	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1385	462	L	P	cTa/cCa	-0,17	0	0	probably_damaging	0,99	deleterious	0	neutral	2,74	deleterious	-4,35	neutral	-1,55	medium_impact	3,46	damaging	0,52	damaging	0,1	deleterious	3,94	23,5	0,18	0,55	disease	0,7	disease	0,84	disease	0,66	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	2,1	0,56	0,9	3,12	8,28	N	0,27	N	0,86	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7290	7290	A	C	MI.4846	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1387	463	T	P	Aca/Cca	-1,32	0	0	benign	0,13	deleterious	0	neutral	2,96	neutral	-1,83	neutral	-0,74	medium_impact	3,15	damaging	0,57	neutral	0,32	neutral	1,79	14,91	0,14	0,55	disease	0,6	disease	0,8	disease	0,62	disease	0,78	6	deleterious	1	neutral	0,44	deleterious	1	neutral	0,28	medium_impact	0,02	low_impact	-1,48	medium_impact	1,81	0,56	0,9	12,67	43,62	N	0,33	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7290	7290	A	T	MI.4847	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1387	463	T	S	Aca/Tca	-1,32	0	0	benign	0,01	deleterious	0	neutral	2,99	neutral	-0,54	neutral	-0,36	low_impact	1,64	neutral	0,68	neutral	0,51	neutral	1,41	12,82	0,4	0,55	neutral	0,37	neutral	0,43	neutral	0,38	neutral	0,47	1	deleterious	1	deleterious	0,5	neutral	-2	neutral	0,12	medium_impact	1,12	low_impact	-1,48	medium_impact	0,42	0,65	0,9	12,67	43,62	N	0,49	N	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7290	7290	A	G	MI.4848	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1387	463	T	A	Aca/Gca	-1,32	0	0	benign	0	deleterious	0,03	neutral	3,08	neutral	0,34	neutral	-0,09	low_impact	1,64	neutral	0,75	neutral	0,6	deleterious	0,46	7,13	0,46	0,55	neutral	0,2	neutral	0,34	neutral	0,39	neutral	0,44	1	neutral	0,97	deleterious	0,52	neutral	-2	neutral	0,08	high_impact	2,07	medium_impact	-0,65	medium_impact	0,42	0,44	0,9	12,67	43,62	N	0,5	N	0,63	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7291	7291	C	T	MI.4849	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1388	463	T	M	aCa/aTa	0,06	0	0	benign	0,01	neutral	0,08	neutral	2,98	neutral	2,64	neutral	0,52	neutral_impact	0,46	neutral	0,69	neutral	0,67	deleterious	0,87	9,89	0,31	0,55	neutral	0,27	neutral	0,35	neutral	0,26	neutral	0,45	1	neutral	0,92	deleterious	0,54	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	-0,4	medium_impact	-0,67	0,72	0,9	12,67	43,62	N	0,51	P	0,8	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8755	8755	A	G	MI.485	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	229	77	I	V	Att/Gtt	-2,65	0	0	benign	0,03	neutral	0,35	neutral	4,45	neutral	-0,59	neutral	-0,41	neutral_impact	0,09	neutral	0,83	neutral	0,8	neutral	-0,6	0,13	0,39	0,65	neutral	0,34	neutral	0,14	neutral	0,36	neutral	0,29	4	neutral	0,63	deleterious	0,66	neutral	-6	neutral	0,13	medium_impact	0,68	medium_impact	0,14	low_impact	-1,02	0,51	0,9	27,43	20,89	N	0,42	N	0,38	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7291	7291	C	A	MI.4850	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1388	463	T	K	aCa/aAa	0,06	0	0	benign	0,03	deleterious	0	neutral	2,96	neutral	-0,96	neutral	-0,58	medium_impact	3,15	neutral	0,65	neutral	0,35	deleterious	2,71	20,8	0,22	0,55	neutral	0,49	disease	0,73	disease	0,63	disease	0,74	5	deleterious	1	deleterious	0,49	deleterious	1	neutral	0,24	medium_impact	0,66	low_impact	-1,48	medium_impact	1,81	0,71	0,9	12,67	43,62	N	0,38	N	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7293	7293	G	T	MI.4851	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1390	464	A	S	Gca/Tca	-2,94	0	0	probably_damaging	0,99	neutral	0,49	neutral	3,05	neutral	0,23	neutral	0,17	neutral_impact	0,66	damaging	0,54	damaging	0,11	deleterious	1,82	15,12	0,41	0,55	neutral	0,19	neutral	0,2	neutral	0,27	neutral	0,35	3	deleterious	0,99	neutral	0,25	neutral	-2	deleterious	0,63	low_impact	-2,64	medium_impact	0,18	medium_impact	-0,49	0,87	0,9	1,95	6,68	N	0,34	N	0,61	polymorphism	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7293	7293	G	C	MI.4852	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1390	464	A	P	Gca/Cca	-2,94	0	0	probably_damaging	1	deleterious	0	neutral	2,66	deleterious	-5,35	neutral	-0,93	high_impact	4,05	damaging	0,52	damaging	0,04	deleterious	4,03	23,6	0,11	0,55	disease	0,71	disease	0,91	disease	0,73	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,64	0,84	0,9	1,95	6,68	N	0,33	N	0,85	polymorphism	0,96	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7293	7293	G	A	MI.4853	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1390	464	A	T	Gca/Aca	-2,94	0	0	probably_damaging	0,99	deleterious	0,01	neutral	2,67	deleterious	-4,15	neutral	-0,46	high_impact	3,71	damaging	0,57	damaging	0,06	deleterious	4,31	24	0,39	0,55	disease	0,51	disease	0,64	disease	0,54	disease	0,59	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,64	medium_impact	-0,92	high_impact	2,33	0,74	0,9	1,95	6,68	N	0,32	N	0,23	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7294	7294	C	T	MI.4854	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1391	464	A	V	gCa/gTa	9,29	1	0	probably_damaging	0,99	deleterious	0	neutral	2,68	deleterious	-3,88	neutral	-1,05	high_impact	4,05	damaging	0,55	damaging	0,04	deleterious	4,54	24,3	0,34	0,55	disease	0,66	disease	0,82	disease	0,62	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-2,64	low_impact	-1,48	high_impact	2,64	0,73	0,9	1,95	6,68	P	0,51	P	0,75	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7294	7294	C	A	MI.4855	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1391	464	A	E	gCa/gAa	9,29	1	0	probably_damaging	1	deleterious	0,01	neutral	2,65	deleterious	-5,95	neutral	-0,78	high_impact	4,05	damaging	0,56	damaging	0,06	deleterious	4,64	24,5	0,16	0,55	disease	0,76	disease	0,9	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,58	medium_impact	-0,92	high_impact	2,64	0,81	0,9	1,95	6,68	P	0,5	N	0,77	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7294	7294	C	G	MI.4856	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1391	464	A	G	gCa/gGa	9,29	1	0	probably_damaging	0,97	neutral	0,3	neutral	3,49	neutral	1,52	neutral	-0,04	low_impact	1,46	damaging	0,54	damaging	0,12	deleterious	2,28	18,01	0,23	0,55	neutral	0,29	neutral	0,39	neutral	0,33	neutral	0,44	1	neutral	0,98	neutral	0,17	neutral	-2	deleterious	0,64	low_impact	-2,18	medium_impact	-0,01	medium_impact	0,25	0,81	0,9	1,95	6,68	P	0,6	P	0,56	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7296	7296	G	A	MI.4857	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1393	465	V	M	Gta/Ata	-8,93	0	0	benign	0,02	neutral	0,13	neutral	2,91	neutral	-0,54	neutral	-0,55	low_impact	1,82	neutral	0,65	neutral	0,66	deleterious	0,74	9,07	0,47	0,55	neutral	0,45	disease	0,58	neutral	0,33	neutral	0,49	0	neutral	0,87	deleterious	0,56	neutral	-6	neutral	0,13	medium_impact	0,83	medium_impact	-0,27	medium_impact	0,58	0,9	0,95	10,33	43,73	N	0,47	N	0,77	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7296	7296	G	C	MI.4858	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1393	465	V	L	Gta/Cta	-8,93	0	0	benign	0,01	neutral	0,26	neutral	3,01	neutral	3,88	neutral	-0,5	medium_impact	2,1	damaging	0,59	neutral	0,59	deleterious	0,57	7,92	0,43	0,55	neutral	0,19	disease	0,66	neutral	0,29	neutral	0,44	1	neutral	0,74	deleterious	0,63	neutral	-3	neutral	0,12	medium_impact	1,12	medium_impact	-0,06	medium_impact	0,84	0,7	0,9	10,33	43,73	N	0,45	N	0,55	polymorphism	0,99	0,02	rs28625344	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7296	7296	G	T	MI.4859	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1393	465	V	L	Gta/Tta	-8,93	0	0	benign	0,01	neutral	0,26	neutral	3,01	neutral	3,88	neutral	-0,5	medium_impact	2,1	damaging	0,59	neutral	0,59	deleterious	0,67	8,62	0,43	0,55	neutral	0,19	disease	0,66	neutral	0,29	neutral	0,44	1	neutral	0,74	deleterious	0,63	neutral	-3	neutral	0,12	medium_impact	1,12	medium_impact	-0,06	medium_impact	0,84	0,7	0,9	10,33	43,73	N	0,47	N	0,55	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8755	8755	A	C	MI.486	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	229	77	I	L	Att/Ctt	-2,65	0	0	benign	0,03	neutral	1	neutral	4,54	neutral	0,37	neutral	0,02	neutral_impact	-0,75	neutral	0,87	neutral	0,96	neutral	-0,92	0,02	0,24	0,65	neutral	0,33	neutral	0,2	neutral	0,28	neutral	0,37	3	neutral	0,03	deleterious	0,99	neutral	-6	neutral	0,14	medium_impact	0,68	high_impact	1,98	low_impact	-1,74	0,55	0,9	27,43	20,89	N	0,29	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7297	7297	T	C	MI.4860	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1394	465	V	A	gTa/gCa	4,21	1	0	benign	0,2	neutral	0,17	neutral	2,99	neutral	0,55	neutral	-1	medium_impact	2,88	neutral	0,62	neutral	0,62	neutral	0,9	10,07	0,37	0,55	neutral	0,34	disease	0,6	neutral	0,4	neutral	0,48	0	neutral	0,8	deleterious	0,49	neutral	-3	neutral	0,21	medium_impact	-0,19	medium_impact	-0,19	medium_impact	1,56	0,55	0,9	10,33	43,73	P	0,57	P	0,47	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7297	7297	T	A	MI.4861	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1394	465	V	E	gTa/gAa	4,21	1	0	benign	0,3	deleterious	0	neutral	2,85	neutral	1,62	neutral	-1,66	high_impact	4,24	neutral	0,62	neutral	0,49	deleterious	3,18	22,7	0,18	0,55	disease	0,61	disease	0,91	disease	0,73	disease	0,83	7	deleterious	1	neutral	0,35	deleterious	2	neutral	0,37	medium_impact	-0,41	low_impact	-1,48	high_impact	2,82	0,59	0,9	10,33	43,73	N	0,46	N	0,83	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7297	7297	T	G	MI.4862	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1394	465	V	G	gTa/gGa	4,21	1	0	benign	0,29	deleterious	0	neutral	2,91	neutral	-0,72	neutral	-1,96	high_impact	3,54	neutral	0,63	neutral	0,58	deleterious	2,26	17,89	0,21	0,55	neutral	0,21	disease	0,81	disease	0,61	disease	0,76	5	deleterious	1	neutral	0,36	deleterious	2	neutral	0,4	medium_impact	-0,39	low_impact	-1,48	high_impact	2,17	0,59	0,9	10,33	43,73	P	0,51	P	0,72	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7299	7299	A	C	MI.4863	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1396	466	M	L	Ata/Cta	-5,01	0	0	benign	0	neutral	0,53	neutral	3,31	neutral	2,91	neutral	0,2	neutral_impact	0,42	neutral	0,76	neutral	0,95	neutral	-1,02	0,01	0,45	0,55	neutral	0,33	neutral	0,48	neutral	0,31	neutral	0,47	1	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,22	medium_impact	-0,71	0,46	0,9	14,62	41,08	N	0,38	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7299	7299	A	T	MI.4864	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1396	466	M	L	Ata/Tta	-5,01	0	0	benign	0	neutral	0,53	neutral	3,31	neutral	2,91	neutral	0,2	neutral_impact	0,42	neutral	0,76	neutral	0,95	neutral	-0,93	0,02	0,45	0,55	neutral	0,33	neutral	0,48	neutral	0,31	neutral	0,47	1	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,22	medium_impact	-0,71	0,46	0,9	14,62	41,08	N	0,38	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7299	7299	A	G	MI.4865	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1396	466	M	V	Ata/Gta	-5,01	0	0	benign	0	neutral	0,21	neutral	3,12	neutral	-0,24	neutral	-0,18	low_impact	1,24	neutral	0,79	neutral	0,95	neutral	-0,27	0,78	0,48	0,55	neutral	0,16	disease	0,7	neutral	0,37	disease	0,53	1	neutral	0,79	deleterious	0,61	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	-0,13	medium_impact	0,05	0,38	0,9	14,62	41,08	N	0,35	N	0,18	polymorphism	1	0,01	rs879071265	.	.	.	.	.	COSM1155675	.	.	.	.	.	.	.	.
chrM	7300	7300	T	A	MI.4866	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1397	466	M	K	aTa/aAa	4,67	1	0	benign	0,01	deleterious	0	neutral	2,94	neutral	-2,97	neutral	-1,37	medium_impact	3,25	neutral	0,62	neutral	0,41	deleterious	2,35	18,49	0,23	0,55	neutral	0,44	disease	0,89	disease	0,68	disease	0,83	6	deleterious	1	deleterious	0,5	deleterious	1	neutral	0,26	medium_impact	1,12	low_impact	-1,48	medium_impact	1,9	0,44	0,9	14,62	41,08	P	0,52	P	0,64	disease_causing	0,81	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7300	7300	T	C	MI.4867	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1397	466	M	T	aTa/aCa	4,67	1	0	benign	0,01	deleterious	0,01	neutral	2,97	neutral	-2,03	neutral	-0,98	medium_impact	1,97	neutral	0,7	neutral	0,8	neutral	1,24	11,96	0,35	0,55	neutral	0,26	disease	0,69	disease	0,59	disease	0,7	4	deleterious	0,99	deleterious	0,5	deleterious	1	neutral	0,17	medium_impact	1,12	medium_impact	-0,92	medium_impact	0,72	0,41	0,9	14,62	41,08	P	0,55	P	0,59	polymorphism	0,65	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7301	7301	A	C	MI.4868	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1398	466	M	I	atA/atC	7,44	1	0	benign	0	neutral	1	neutral	3,12	neutral	0,06	neutral	0,05	neutral_impact	-0,72	neutral	0,73	neutral	0,98	neutral	-1,16	0,01	0,48	0,55	neutral	0,2	disease	0,54	neutral	0,33	neutral	0,43	1	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,07	high_impact	1,86	low_impact	-1,76	0,54	0,9	14,62	41,08	N	0,5	N	0	disease_causing	0,64	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7301	7301	A	T	MI.4869	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1398	466	M	I	atA/atT	7,44	1	0	benign	0	neutral	1	neutral	3,12	neutral	0,06	neutral	0,05	neutral_impact	-0,72	neutral	0,73	neutral	0,98	neutral	-1,1	0,01	0,48	0,55	neutral	0,2	disease	0,54	neutral	0,33	neutral	0,43	1	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,07	high_impact	1,86	low_impact	-1,76	0,54	0,9	14,62	41,08	N	0,51	P	0	disease_causing	0,64	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8755	8755	A	T	MI.487	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	229	77	I	F	Att/Ttt	-2,65	0	0	benign	0,35	neutral	0,36	neutral	4,28	neutral	0,77	neutral	-2,38	neutral_impact	0,46	neutral	0,91	neutral	0,62	deleterious	1,88	15,49	0,29	0,65	neutral	0,3	disease	0,56	neutral	0,4	neutral	0,46	1	neutral	0,57	deleterious	0,51	neutral	-6	neutral	0,33	medium_impact	-0,5	medium_impact	0,15	medium_impact	-0,7	0,59	0,9	27,43	20,89	N	0,32	N	0,43	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7302	7302	T	G	MI.4870	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1399	467	L	V	Tta/Gta	-2,48	0	0	probably_damaging	0,94	deleterious	0,02	neutral	2,84	neutral	-1,1	neutral	-0,3	medium_impact	2,31	neutral	0,71	neutral	0,9	deleterious	2,27	18	0,35	0,55	neutral	0,21	neutral	0,48	neutral	0,28	neutral	0,44	1	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,61	low_impact	-1,88	medium_impact	-0,75	medium_impact	1,03	0,57	0,9	9,16	29,82	N	0,48	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7302	7302	T	A	MI.4871	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1399	467	L	M	Tta/Ata	-2,48	0	0	probably_damaging	1	neutral	0,98	neutral	2,77	neutral	1,04	neutral	0,17	neutral_impact	-0,1	neutral	0,68	neutral	0,72	neutral	0,99	10,62	0,26	0,55	neutral	0,42	neutral	0,16	neutral	0,25	neutral	0,29	4	deleterious	1	deleterious	0,49	neutral	-2	deleterious	0,64	low_impact	-3,58	medium_impact	1,13	low_impact	-1,19	0,63	0,9	9,16	29,82	N	0,28	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7303	7303	T	G	MI.4872	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1400	467	L	W	tTa/tGa	-1,78	0	0	probably_damaging	1	neutral	0,1	neutral	2,68	deleterious	-3,8	neutral	-0,5	medium_impact	2,86	damaging	0,59	damaging	0,13	deleterious	2,76	21,2	0,14	0,55	disease	0,79	disease	0,75	neutral	0,37	disease	0,66	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,77	low_impact	-3,58	medium_impact	-0,34	medium_impact	1,54	0,56	0,9	9,16	29,82	N	0,34	N	0,68	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7303	7303	T	C	MI.4873	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1400	467	L	S	tTa/tCa	-1,78	0	0	probably_damaging	1	deleterious	0,01	neutral	2,71	neutral	-2,5	neutral	-0,87	medium_impact	3	damaging	0,58	damaging	0,18	deleterious	3,85	23,4	0,23	0,55	neutral	0,48	disease	0,65	disease	0,55	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,71	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,67	0,7	0,9	9,16	29,82	N	0,33	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7304	7304	A	C	MI.4874	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1401	467	L	F	ttA/ttC	7,44	0,98	0	probably_damaging	0,99	neutral	0,59	neutral	2,77	neutral	0,22	neutral	0,18	neutral_impact	0,77	neutral	0,66	neutral	0,3	neutral	1,35	12,51	0,38	0,55	neutral	0,33	neutral	0,3	neutral	0,23	neutral	0,46	1	deleterious	0,99	neutral	0,3	neutral	-2	deleterious	0,66	low_impact	-2,64	medium_impact	0,28	medium_impact	-0,39	0,59	0,9	9,16	29,82	P	0,54	P	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7304	7304	A	T	MI.4875	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1401	467	L	F	ttA/ttT	7,44	0,98	0	probably_damaging	0,99	neutral	0,59	neutral	2,77	neutral	0,22	neutral	0,18	neutral_impact	0,77	neutral	0,66	neutral	0,3	neutral	1,46	13,09	0,38	0,55	neutral	0,33	neutral	0,3	neutral	0,23	neutral	0,46	1	deleterious	0,99	neutral	0,3	neutral	-2	deleterious	0,66	low_impact	-2,64	medium_impact	0,28	medium_impact	-0,39	0,59	0,9	9,16	29,82	P	0,54	P	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7305	7305	A	G	MI.4876	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1402	468	M	V	Ata/Gta	-3,4	0	0	benign	0,01	deleterious	0	neutral	2,96	neutral	-0,16	neutral	-0,44	medium_impact	3,34	neutral	0,74	damaging	0,16	deleterious	2,66	20,6	0,42	0,55	neutral	0,22	disease	0,85	disease	0,52	disease	0,73	5	deleterious	1	deleterious	0,5	deleterious	1	neutral	0,18	medium_impact	1,12	low_impact	-1,48	medium_impact	1,99	0,36	0,9	3,51	7,7	N	0,36	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7305	7305	A	C	MI.4877	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1402	468	M	L	Ata/Cta	-3,4	0	0	benign	0	neutral	0,2	neutral	3,11	neutral	1,73	neutral	0,08	neutral_impact	-0,4	neutral	0,67	neutral	0,31	neutral	1,73	14,57	0,37	0,55	neutral	0,19	disease	0,69	neutral	0,39	disease	0,5	0	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,16	high_impact	2,07	medium_impact	-0,14	low_impact	-1,47	0,32	0,9	3,51	7,7	N	0,39	N	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	0,45	A7305C	Prostate Cancer	+	-	Reported	1
chrM	7305	7305	A	T	MI.4878	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1402	468	M	L	Ata/Tta	-3,4	0	0	benign	0	neutral	0,2	neutral	3,11	neutral	1,73	neutral	0,08	neutral_impact	-0,4	neutral	0,67	neutral	0,31	neutral	1,8	14,96	0,37	0,55	neutral	0,19	disease	0,69	neutral	0,39	disease	0,5	0	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,16	high_impact	2,07	medium_impact	-0,14	low_impact	-1,47	0,32	0,9	3,51	7,7	N	0,4	N	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7306	7306	T	C	MI.4879	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1403	468	M	T	aTa/aCa	2,37	0,98	0	benign	0,09	deleterious	0	neutral	2,94	neutral	-1,82	neutral	-0,94	medium_impact	3,34	neutral	0,67	damaging	0,14	deleterious	3,08	22,5	0,4	0,55	neutral	0,31	disease	0,78	disease	0,58	disease	0,76	5	deleterious	1	neutral	0,46	deleterious	1	neutral	0,25	medium_impact	0,19	low_impact	-1,48	medium_impact	1,99	0,34	0,9	3,51	7,7	N	0,49	N	0,8	polymorphism	0,84	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8756	8756	T	C	MI.488	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	230	77	I	T	aTt/aCt	-4,96	0	0,01	benign	0	neutral	0,25	neutral	4,32	neutral	-0,72	neutral	-2,17	low_impact	0,85	neutral	0,96	neutral	0,81	neutral	-0,18	1,22	0,29	0,65	neutral	0,28	neutral	0,25	neutral	0,38	neutral	0,42	2	neutral	0,75	deleterious	0,63	neutral	-6	neutral	0,12	high_impact	2,09	medium_impact	0,02	medium_impact	-0,37	0,7	0,9	27,43	20,89	N	0,42	N	0,08	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7306	7306	T	A	MI.4880	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1403	468	M	K	aTa/aAa	2,37	0,98	0	benign	0,06	deleterious	0	neutral	2,91	neutral	-2,93	neutral	-1,24	medium_impact	3,34	neutral	0,64	damaging	0,07	deleterious	4,14	23,8	0,22	0,55	neutral	0,16	disease	0,93	disease	0,66	disease	0,84	7	deleterious	1	deleterious	0,47	deleterious	1	neutral	0,27	medium_impact	0,37	low_impact	-1,48	medium_impact	1,99	0,49	0,9	3,51	7,7	N	0,43	N	0,93	disease_causing	0,58	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7307	7307	A	T	MI.4881	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1404	468	M	I	atA/atT	7,44	1	0	benign	0,01	deleterious	0,02	neutral	2,95	neutral	0,26	neutral	-0,15	medium_impact	2,29	neutral	0,68	damaging	0,18	deleterious	3,35	22,9	0,41	0,55	neutral	0,25	disease	0,9	neutral	0,5	disease	0,72	4	neutral	0,98	deleterious	0,51	deleterious	1	neutral	0,22	medium_impact	1,12	medium_impact	-0,75	medium_impact	1,02	0,54	0,9	3,51	7,7	P	0,51	P	0,85	disease_causing	0,59	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7307	7307	A	C	MI.4882	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1404	468	M	I	atA/atC	7,44	1	0	benign	0,01	deleterious	0,02	neutral	2,95	neutral	0,26	neutral	-0,15	medium_impact	2,29	neutral	0,68	damaging	0,18	deleterious	3,29	22,8	0,41	0,55	neutral	0,25	disease	0,9	neutral	0,5	disease	0,72	4	neutral	0,98	deleterious	0,51	deleterious	1	neutral	0,22	medium_impact	1,12	medium_impact	-0,75	medium_impact	1,02	0,54	0,9	3,51	7,7	P	0,51	P	0,85	disease_causing	0,59	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7308	7308	A	C	MI.4883	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1405	469	I	L	Att/Ctt	0,52	0,21	0	benign	0	neutral	1	neutral	3,02	neutral	0,03	neutral	-0,18	neutral_impact	-0,3	neutral	0,73	neutral	0,86	neutral	-0,11	1,63	0,36	0,55	neutral	0,17	neutral	0,3	neutral	0,23	neutral	0,45	1	neutral	0	deleterious	1	neutral	-6	neutral	0,08	high_impact	2,07	high_impact	1,86	low_impact	-1,38	0,66	0,9	9,16	11,34	N	0,27	N	0,3	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7308	7308	A	T	MI.4884	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1405	469	I	F	Att/Ttt	0,52	0,21	0	benign	0,07	neutral	0,08	neutral	2,86	deleterious	-3,85	neutral	-0,79	low_impact	1,5	neutral	0,69	neutral	0,71	neutral	0,92	10,2	0,35	0,55	neutral	0,21	disease	0,6	neutral	0,34	neutral	0,44	1	neutral	0,91	deleterious	0,51	neutral	-6	neutral	0,16	medium_impact	0,3	medium_impact	-0,4	medium_impact	0,29	0,71	0,9	9,16	11,34	N	0,46	N	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7308	7308	A	G	MI.4885	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1405	469	I	V	Att/Gtt	0,52	0,21	0	benign	0	neutral	0,32	neutral	3,02	neutral	-2,16	neutral	-0,22	low_impact	0,94	neutral	0,85	neutral	1	deleterious	-0,02	2,39	0,55	0,6	neutral	0,19	neutral	0,29	neutral	0,36	neutral	0,43	1	neutral	0,68	deleterious	0,66	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,01	medium_impact	-0,23	0,41	0,9	9,16	11,34	N	0,42	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7309	7309	T	A	MI.4886	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1406	469	I	N	aTt/aAt	-0,63	0	0	benign	0,18	neutral	0,09	neutral	2,77	deleterious	-6,38	neutral	-1,81	medium_impact	3,34	neutral	0,64	neutral	0,43	deleterious	2,94	22	0,27	0,55	disease	0,56	disease	0,76	disease	0,61	disease	0,72	4	neutral	0,9	neutral	0,46	neutral	-3	neutral	0,32	medium_impact	-0,14	medium_impact	-0,37	medium_impact	1,99	0,63	0,9	9,16	11,34	N	0,4	N	0,75	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7309	7309	T	G	MI.4887	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1406	469	I	S	aTt/aGt	-0,63	0	0	benign	0,02	neutral	0,07	neutral	2,78	deleterious	-5,31	neutral	-1,47	medium_impact	2,99	neutral	0,68	neutral	0,5	deleterious	2,49	19,43	0,3	0,55	neutral	0,38	disease	0,74	disease	0,58	disease	0,69	4	neutral	0,93	deleterious	0,53	neutral	-3	neutral	0,17	medium_impact	0,83	medium_impact	-0,43	medium_impact	1,66	0,59	0,9	9,16	11,34	N	0,42	N	0,63	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7309	7309	T	C	MI.4888	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1406	469	I	T	aTt/aCt	-0,63	0	0	benign	0,02	deleterious	0,01	neutral	2,81	deleterious	-4,52	neutral	-1,21	medium_impact	2,79	neutral	0,78	neutral	0,91	deleterious	0,58	8,02	0,45	0,55	neutral	0,27	disease	0,52	disease	0,51	disease	0,52	0	deleterious	0,99	deleterious	0,5	deleterious	1	neutral	0,15	medium_impact	0,83	medium_impact	-0,92	medium_impact	1,48	0,61	0,9	9,16	11,34	N	0,42	N	0,74	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7310	7310	T	A	MI.4889	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1407	469	I	M	atT/atA	4,67	0,7	0,01	benign	0	neutral	0,34	neutral	2,8	neutral	-2,82	neutral	-0,28	neutral_impact	-0,02	neutral	0,69	neutral	0,86	deleterious	0,53	7,68	0,39	0,55	neutral	0,3	neutral	0,28	neutral	0,3	neutral	0,44	1	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,03	low_impact	-1,12	0,7	0,9	9,16	11,34	N	0,49	N	0,52	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8756	8756	T	A	MI.489	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	230	77	I	N	aTt/aAt	-4,96	0	0,01	benign	0,17	deleterious	0,02	neutral	4,25	deleterious	-3,31	deleterious	-4,37	low_impact	1,53	neutral	0,86	neutral	0,45	deleterious	2,42	18,98	0,2	0,65	disease	0,79	disease	0,65	disease	0,51	disease	0,57	1	neutral	0,98	neutral	0,43	neutral	-2	neutral	0,34	medium_impact	-0,1	medium_impact	-0,66	medium_impact	0,21	0,64	0,9	27,43	20,89	N	0,36	N	0,58	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7310	7310	T	G	MI.4890	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1407	469	I	M	atT/atG	4,67	0,7	0,01	benign	0	neutral	0,34	neutral	2,8	neutral	-2,82	neutral	-0,28	neutral_impact	-0,02	neutral	0,69	neutral	0,86	deleterious	0,16	4,28	0,39	0,55	neutral	0,3	neutral	0,28	neutral	0,3	neutral	0,44	1	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,03	low_impact	-1,12	0,7	0,9	9,16	11,34	N	0,48	N	0,52	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7311	7311	T	C	MI.4891	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1408	470	F	L	Ttc/Ctc	-8,93	0	0	benign	0,04	neutral	0,07	neutral	2,98	neutral	-1,41	neutral	-1,04	medium_impact	3,13	neutral	0,68	neutral	0,68	neutral	1,09	11,13	0,4	0,55	neutral	0,25	disease	0,79	neutral	0,4	disease	0,53	1	neutral	0,93	deleterious	0,52	neutral	-3	neutral	0,16	medium_impact	0,54	medium_impact	-0,43	medium_impact	1,79	0,52	0,9	11,5	53,78	N	0,48	N	0,63	polymorphism	0,92	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7311	7311	T	A	MI.4892	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1408	470	F	I	Ttc/Atc	-8,93	0	0	benign	0,06	neutral	0,09	neutral	2,98	neutral	-2,23	neutral	-0,99	medium_impact	2,68	neutral	0,66	neutral	0,71	neutral	1,23	11,88	0,25	0,55	neutral	0,37	disease	0,82	neutral	0,38	disease	0,53	1	neutral	0,9	deleterious	0,52	neutral	-3	neutral	0,25	medium_impact	0,37	medium_impact	-0,37	medium_impact	1,38	0,55	0,9	11,5	53,78	N	0,44	N	0,58	polymorphism	0,93	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7311	7311	T	G	MI.4893	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1408	470	F	V	Ttc/Gtc	-8,93	0	0	benign	0,08	deleterious	0,03	neutral	2,94	neutral	-2,29	neutral	-1,19	medium_impact	3,27	neutral	0,64	neutral	0,68	neutral	1,14	11,44	0,28	0,55	neutral	0,31	disease	0,85	neutral	0,4	disease	0,53	1	neutral	0,97	deleterious	0,48	deleterious	1	neutral	0,23	medium_impact	0,24	medium_impact	-0,65	medium_impact	1,92	0,57	0,9	11,5	53,78	N	0,44	N	0,73	polymorphism	0,86	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7312	7312	T	A	MI.4894	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1409	470	F	Y	tTc/tAc	7,44	1	0	benign	0	neutral	0,34	neutral	3,02	deleterious	-3,05	neutral	-0,36	low_impact	1,65	neutral	0,73	neutral	0,81	neutral	1,01	10,74	0,33	0,55	neutral	0,17	disease	0,55	neutral	0,3	neutral	0,42	2	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,03	medium_impact	0,43	0,64	0,9	11,5	53,78	P	0,62	P	0,13	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7312	7312	T	G	MI.4895	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1409	470	F	C	tTc/tGc	7,44	1	0	possibly_damaging	0,69	deleterious	0	neutral	2,82	deleterious	-4,74	neutral	-1,62	high_impact	4	neutral	0,68	neutral	0,47	deleterious	3,96	23,6	0,24	0,55	disease	0,81	disease	0,89	disease	0,54	disease	0,73	5	deleterious	1	neutral	0,16	deleterious	5	deleterious	0,67	low_impact	-1,08	low_impact	-1,48	high_impact	2,59	0,36	0,9	11,5	53,78	P	0,5	N	0,78	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7312	7312	T	C	MI.4896	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1409	470	F	S	tTc/tCc	7,44	1	0	benign	0	deleterious	0	neutral	2,86	deleterious	-3,44	neutral	-1,74	high_impact	4	neutral	0,71	neutral	0,49	deleterious	2,61	20,2	0,36	0,55	disease	0,66	disease	0,86	disease	0,53	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	2	neutral	0,24	high_impact	2,07	low_impact	-1,48	high_impact	2,59	0,58	0,9	11,5	53,78	P	0,56	P	0,83	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7313	7313	C	G	MI.4897	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1410	470	F	L	ttC/ttG	4,67	1	0	benign	0,04	neutral	0,07	neutral	2,98	neutral	-1,41	neutral	-1,04	medium_impact	3,13	neutral	0,68	neutral	0,68	neutral	1,37	12,61	0,4	0,55	neutral	0,25	disease	0,79	neutral	0,4	disease	0,53	1	neutral	0,93	deleterious	0,52	neutral	-3	neutral	0,16	medium_impact	0,54	medium_impact	-0,43	medium_impact	1,79	0,52	0,9	11,5	53,78	P	0,61	P	0,63	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7313	7313	C	A	MI.4898	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1410	470	F	L	ttC/ttA	4,67	1	0	benign	0,04	neutral	0,07	neutral	2,98	neutral	-1,41	neutral	-1,04	medium_impact	3,13	neutral	0,68	neutral	0,68	neutral	1,7	14,4	0,4	0,55	neutral	0,25	disease	0,79	neutral	0,4	disease	0,53	1	neutral	0,93	deleterious	0,52	neutral	-3	neutral	0,16	medium_impact	0,54	medium_impact	-0,43	medium_impact	1,79	0,52	0,9	11,5	53,78	P	0,61	P	0,63	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7314	7314	A	C	MI.4899	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1411	471	M	L	Atg/Ctg	-4,09	0	0	possibly_damaging	0,7	neutral	0,19	neutral	3,11	neutral	2,08	neutral	0,26	neutral_impact	0,6	neutral	0,66	neutral	0,7	deleterious	2,28	18,05	0,47	0,55	neutral	0,23	disease	0,71	neutral	0,36	disease	0,53	1	neutral	0,85	neutral	0,25	neutral	-3	deleterious	0,49	low_impact	-1,1	medium_impact	-0,16	medium_impact	-0,55	0,54	0,9	5,65	41,36	N	0,42	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8548	8548	T	A	MI.49	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	22	8	S	T	Tca/Aca	-0,1	0,83	0	benign	0,08	neutral	1	neutral	4,67	neutral	-0,68	neutral	-1,31	low_impact	1,16	neutral	0,9	neutral	0,59	neutral	1,67	14,23	0,33	0,65	neutral	0,41	neutral	0,38	neutral	0,28	neutral	0,44	1	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,26	medium_impact	0,25	high_impact	1,98	medium_impact	-0,1	0,65	0,9	21,24	17,86	N	0,27	N	0,33	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8756	8756	T	G	MI.490	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	230	77	I	S	aTt/aGt	-4,96	0	0,01	benign	0,07	neutral	0,33	neutral	4,28	neutral	-1,53	deleterious	-3,41	low_impact	1,06	neutral	0,9	neutral	0,67	deleterious	2,18	17,37	0,24	0,65	disease	0,51	disease	0,53	disease	0,56	neutral	0,49	0	neutral	0,64	deleterious	0,63	neutral	-6	neutral	0,21	medium_impact	0,31	medium_impact	0,12	medium_impact	-0,19	0,61	0,9	27,43	20,89	N	0,34	N	0,41	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7314	7314	A	T	MI.4900	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1411	471	M	L	Atg/Ttg	-4,09	0	0	possibly_damaging	0,7	neutral	0,19	neutral	3,11	neutral	2,08	neutral	0,26	neutral_impact	0,6	neutral	0,66	neutral	0,7	deleterious	2,26	17,89	0,47	0,55	neutral	0,23	disease	0,71	neutral	0,36	disease	0,53	1	neutral	0,85	neutral	0,25	neutral	-3	deleterious	0,49	low_impact	-1,1	medium_impact	-0,16	medium_impact	-0,55	0,54	0,9	5,65	41,36	N	0,42	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7314	7314	A	G	MI.4901	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1411	471	M	V	Atg/Gtg	-4,09	0	0	possibly_damaging	0,79	neutral	0,16	neutral	3,07	neutral	2,7	neutral	0,53	low_impact	1,65	neutral	0,65	neutral	0,59	deleterious	2,7	20,8	0,55	0,6	neutral	0,17	disease	0,72	neutral	0,36	disease	0,53	1	neutral	0,9	neutral	0,19	neutral	-3	deleterious	0,53	low_impact	-1,3	medium_impact	-0,21	medium_impact	0,43	0,58	0,9	5,65	41,36	N	0,43	N	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7315	7315	T	C	MI.4902	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1412	471	M	T	aTg/aCg	6,75	1	0	possibly_damaging	0,9	deleterious	0,02	neutral	3,01	neutral	-0,15	neutral	-0,63	low_impact	0,93	neutral	0,73	neutral	0,75	deleterious	3,04	22,4	0,44	0,55	neutral	0,24	disease	0,69	disease	0,58	disease	0,55	1	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,67	low_impact	-1,65	medium_impact	-0,75	medium_impact	-0,24	0,43	0,9	5,65	41,36	N	0,45	N	0,56	disease_causing	0,92	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7315	7315	T	A	MI.4903	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1412	471	M	K	aTg/aAg	6,75	1	0	possibly_damaging	0,9	deleterious	0	neutral	2,99	neutral	-1,46	neutral	-1,27	medium_impact	2,46	damaging	0,54	neutral	0,36	deleterious	4,22	23,9	0,23	0,55	neutral	0,21	disease	0,91	disease	0,67	disease	0,83	7	deleterious	1	neutral	0,05	deleterious	4	deleterious	0,73	low_impact	-1,65	low_impact	-1,48	medium_impact	1,17	0,61	0,9	5,65	41,36	P	0,5	N	0,74	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7316	7316	G	T	MI.4904	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1413	471	M	I	atG/atT	7,44	1	0	possibly_damaging	0,84	neutral	1	neutral	3,23	neutral	6,69	neutral	0,83	neutral_impact	-2,16	neutral	0,77	neutral	0,98	neutral	1,01	10,74	0,45	0,55	neutral	0,15	neutral	0,3	neutral	0,29	neutral	0,43	2	neutral	0,84	deleterious	0,58	neutral	-3	deleterious	0,55	low_impact	-1,43	high_impact	1,86	low_impact	-3,09	0,57	0,9	5,65	41,36	N	0,5	N	0,01	disease_causing	0,98	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7316	7316	G	C	MI.4905	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1413	471	M	I	atG/atC	7,44	1	0	possibly_damaging	0,84	neutral	1	neutral	3,23	neutral	6,69	neutral	0,83	neutral_impact	-2,16	neutral	0,77	neutral	0,98	neutral	0,89	10,05	0,45	0,55	neutral	0,15	neutral	0,3	neutral	0,29	neutral	0,43	2	neutral	0,84	deleterious	0,58	neutral	-3	deleterious	0,55	low_impact	-1,43	high_impact	1,86	low_impact	-3,09	0,57	0,9	5,65	41,36	N	0,5	N	0,01	disease_causing	0,98	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7317	7317	A	C	MI.4906	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1414	472	I	L	Att/Ctt	-3,4	0	0	benign	0,03	neutral	0,77	neutral	3,02	neutral	-1,83	neutral	-0,23	low_impact	1,17	neutral	0,65	neutral	0,72	neutral	-0,23	0,93	0,38	0,55	neutral	0,35	neutral	0,35	neutral	0,21	neutral	0,47	1	neutral	0,17	deleterious	0,87	neutral	-6	neutral	0,12	medium_impact	0,66	medium_impact	0,48	medium_impact	-0,02	0,78	0,9	11,11	14,52	N	0,36	N	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7317	7317	A	T	MI.4907	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1414	472	I	F	Att/Ttt	-3,4	0	0	benign	0,36	deleterious	0,01	neutral	2,84	deleterious	-5,75	neutral	-1,03	medium_impact	2,75	neutral	0,62	neutral	0,46	deleterious	2,13	17,03	0,38	0,55	disease	0,76	disease	0,75	neutral	0,39	disease	0,6	2	deleterious	0,99	neutral	0,33	deleterious	1	deleterious	0,45	medium_impact	-0,52	medium_impact	-0,92	medium_impact	1,44	0,8	0,9	11,11	14,52	N	0,37	N	0,85	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7317	7317	A	G	MI.4908	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1414	472	I	V	Att/Gtt	-3,4	0	0	benign	0,01	neutral	0,33	neutral	2,98	deleterious	-3,66	neutral	-0,24	low_impact	1,58	neutral	0,81	neutral	0,98	neutral	-0,57	0,15	0,67	0,7	neutral	0,23	neutral	0,23	neutral	0,27	neutral	0,44	1	neutral	0,66	deleterious	0,66	neutral	-6	neutral	0,08	medium_impact	1,12	medium_impact	0,02	medium_impact	0,36	0,61	0,9	11,11	14,52	N	0,46	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7318	7318	T	A	MI.4909	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1415	472	I	N	aTt/aAt	-0,63	0	0,01	benign	0,32	deleterious	0	neutral	2,74	deleterious	-7,17	neutral	-1,99	high_impact	3,99	neutral	0,65	neutral	0,39	deleterious	4,39	24,1	0,29	0,55	disease	0,91	disease	0,84	disease	0,61	disease	0,8	6	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,56	medium_impact	-0,45	low_impact	-1,48	high_impact	2,59	0,69	0,9	11,11	14,52	N	0,35	N	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8757	8757	T	G	MI.491	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	231	77	I	M	atT/atG	1,52	0	0	possibly_damaging	0,54	neutral	0,32	neutral	4,36	neutral	-0,61	neutral	-0,76	neutral_impact	-0,4	neutral	0,9	neutral	0,94	neutral	1,34	12,48	0,31	0,65	neutral	0,38	neutral	0,16	neutral	0,31	neutral	0,29	4	neutral	0,67	neutral	0,39	neutral	-3	deleterious	0,45	medium_impact	-0,82	medium_impact	0,11	low_impact	-1,44	0,72	0,9	27,43	20,89	N	0,47	N	0,06	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7318	7318	T	G	MI.4910	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1415	472	I	S	aTt/aGt	-0,63	0	0,01	benign	0,14	deleterious	0	neutral	2,76	deleterious	-6,04	neutral	-1,66	high_impact	3,99	neutral	0,65	neutral	0,41	deleterious	2,81	21,4	0,39	0,55	disease	0,83	disease	0,82	disease	0,59	disease	0,77	5	deleterious	1	neutral	0,43	deleterious	2	neutral	0,34	medium_impact	-0,01	low_impact	-1,48	high_impact	2,59	0,63	0,9	11,11	14,52	N	0,38	N	0,65	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7318	7318	T	C	MI.4911	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1415	472	I	T	aTt/aCt	-0,63	0	0,01	benign	0,01	deleterious	0,01	neutral	2,79	deleterious	-5,55	neutral	-1,32	high_impact	3,54	neutral	0,69	neutral	0,59	neutral	1,75	14,71	0,47	0,55	disease	0,74	disease	0,63	disease	0,51	disease	0,55	1	deleterious	0,99	deleterious	0,5	deleterious	2	neutral	0,23	medium_impact	1,12	medium_impact	-0,92	high_impact	2,17	0,78	0,9	11,11	14,52	N	0,41	N	0,79	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7319	7319	T	A	MI.4912	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1416	472	I	M	atT/atA	5,83	0,89	0	possibly_damaging	0,55	neutral	0,06	neutral	2,8	deleterious	-5,11	neutral	-0,51	medium_impact	2,34	neutral	0,72	neutral	0,71	deleterious	0,76	9,24	0,44	0,55	neutral	0,44	neutral	0,43	neutral	0,29	neutral	0,48	0	neutral	0,94	neutral	0,26	NA	0	neutral	0,37	medium_impact	-0,84	medium_impact	-0,47	medium_impact	1,06	0,83	0,9	11,11	14,52	P	0,55	P	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7319	7319	T	G	MI.4913	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1416	472	I	M	atT/atG	5,83	0,89	0	possibly_damaging	0,55	neutral	0,06	neutral	2,8	deleterious	-5,11	neutral	-0,51	medium_impact	2,34	neutral	0,72	neutral	0,71	deleterious	0,59	8,11	0,44	0,55	neutral	0,44	neutral	0,43	neutral	0,29	neutral	0,48	0	neutral	0,94	neutral	0,26	NA	0	neutral	0,37	medium_impact	-0,84	medium_impact	-0,47	medium_impact	1,06	0,83	0,9	11,11	14,52	P	0,55	P	0,73	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7320	7320	T	C	MI.4914	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1417	473	W	R	Tga/Cga	-6,86	0	0	probably_damaging	1	deleterious	0	neutral	2,82	deleterious	-9,03	deleterious	-4,48	high_impact	4,69	neutral	0,61	damaging	0,04	deleterious	3,69	23,3	0,44	0,55	disease	0,57	disease	0,95	disease	0,74	disease	0,89	8	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,58	low_impact	-1,48	high_impact	3,23	0,32	0,9	NA	NA	N	0,48	N	0,94	polymorphism	0,99	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7320	7320	T	G	MI.4915	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1417	473	W	G	Tga/Gga	-6,86	0	0	probably_damaging	0,99	deleterious	0	neutral	2,82	deleterious	-9,07	deleterious	-4,17	high_impact	4,34	neutral	0,65	damaging	0,06	deleterious	4,01	23,6	0,32	0,55	disease	0,58	disease	0,93	disease	0,7	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,64	low_impact	-1,48	high_impact	2,91	0,34	0,9	NA	NA	N	0,29	N	0,9	polymorphism	0,97	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7321	7321	G	T	MI.4916	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1418	473	W	L	tGa/tTa	7,44	1	0	probably_damaging	0,99	neutral	0,18	neutral	3,01	deleterious	-7,72	deleterious	-4,12	medium_impact	2,96	neutral	0,67	damaging	0,04	deleterious	4,31	24	0,27	0,55	neutral	0,2	disease	0,87	disease	0,55	disease	0,52	0	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,76	low_impact	-2,64	medium_impact	-0,17	medium_impact	1,63	0,31	0,9	NA	NA	N	0,39	N	0,95	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7321	7321	G	C	MI.4917	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1418	473	W	S	tGa/tCa	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,82	deleterious	-8,7	deleterious	-4,47	high_impact	4,34	neutral	0,63	damaging	0,05	deleterious	4,12	23,8	0,3	0,55	neutral	0,43	disease	0,94	disease	0,68	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,58	low_impact	-1,48	high_impact	2,91	0,32	0,9	NA	NA	N	0,38	N	0,88	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7322	7322	A	T	MI.4918	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1419	473	W	C	tgA/tgT	9,29	1	0	probably_damaging	1	deleterious	0,01	neutral	2,8	deleterious	-10,44	deleterious	-4,16	high_impact	4,69	damaging	0,54	damaging	0,05	deleterious	4,29	24	0,33	0,55	disease	0,63	disease	0,93	disease	0,66	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,58	medium_impact	-0,92	high_impact	3,23	0,28	0,9	NA	NA	P	0,47	N	0,88	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7322	7322	A	C	MI.4919	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1419	473	W	C	tgA/tgC	9,29	1	0	probably_damaging	1	deleterious	0,01	neutral	2,8	deleterious	-10,44	deleterious	-4,16	high_impact	4,69	damaging	0,54	damaging	0,05	deleterious	4,17	23,8	0,33	0,55	disease	0,63	disease	0,93	disease	0,66	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,58	medium_impact	-0,92	high_impact	3,23	0,28	0,9	NA	NA	P	0,47	N	0,88	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8757	8757	T	A	MI.492	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	231	77	I	M	atT/atA	1,52	0	0	possibly_damaging	0,54	neutral	0,32	neutral	4,36	neutral	-0,61	neutral	-0,76	neutral_impact	-0,4	neutral	0,9	neutral	0,94	neutral	1,68	14,29	0,31	0,65	neutral	0,38	neutral	0,16	neutral	0,31	neutral	0,29	4	neutral	0,67	neutral	0,39	neutral	-3	deleterious	0,45	medium_impact	-0,82	medium_impact	0,11	low_impact	-1,44	0,72	0,9	27,43	20,89	N	0,48	N	0,06	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7323	7323	G	C	MI.4920	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1420	474	E	Q	Gaa/Caa	2,14	1	0	probably_damaging	0,99	deleterious	0	neutral	2,83	deleterious	-4,26	neutral	-0,91	high_impact	4,76	damaging	0,56	damaging	0,16	deleterious	3,56	23,1	0,38	0,55	neutral	0,27	disease	0,83	disease	0,59	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,64	low_impact	-1,48	high_impact	3,3	0,78	0,9	2,73	6,62	P	0,63	P	0,66	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7323	7323	G	A	MI.4921	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1420	474	E	K	Gaa/Aaa	2,14	1	0	probably_damaging	1	deleterious	0	neutral	2,89	deleterious	-3,34	neutral	-1,19	high_impact	3,61	damaging	0,46	damaging	0,1	deleterious	4,64	24,5	0,26	0,55	neutral	0,2	disease	0,93	neutral	0,41	disease	0,52	0	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,23	0,63	0,9	2,73	6,62	N	0,51	P	0,72	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7324	7324	A	T	MI.4922	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1421	474	E	V	gAa/gTa	9,29	1	0	probably_damaging	1	deleterious	0	neutral	2,94	deleterious	-5,71	neutral	-2,19	high_impact	4,76	damaging	0,49	damaging	0,14	deleterious	4,21	23,9	0,19	0,55	neutral	0,48	disease	0,94	disease	0,63	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,68	0,9	2,73	6,62	P	0,65	P	0,68	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7324	7324	A	G	MI.4923	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1421	474	E	G	gAa/gGa	9,29	1	0	probably_damaging	1	deleterious	0	neutral	2,83	deleterious	-5,18	neutral	-2,13	high_impact	4,42	damaging	0,44	damaging	0,19	deleterious	4,35	24,1	0,24	0,55	neutral	0,45	disease	0,89	disease	0,62	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,98	0,55	0,9	2,73	6,62	P	0,6	P	0,67	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7324	7324	A	C	MI.4924	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1421	474	E	A	gAa/gCa	9,29	1	0	probably_damaging	1	deleterious	0	neutral	2,88	deleterious	-4,41	neutral	-1,86	high_impact	4,76	damaging	0,6	damaging	0,16	deleterious	3,71	23,3	0,16	0,55	neutral	0,3	disease	0,84	disease	0,6	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,73	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,54	0,9	2,73	6,62	P	0,65	P	0,7	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7325	7325	A	C	MI.4925	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1422	474	E	D	gaA/gaC	6,98	1	0	probably_damaging	0,94	neutral	0,1	neutral	2,83	deleterious	-3,84	neutral	-0,84	medium_impact	3,48	damaging	0,5	damaging	0,16	deleterious	3,77	23,4	0,32	0,55	neutral	0,22	disease	0,77	neutral	0,25	neutral	0,48	0	neutral	0,98	neutral	0,08	deleterious	1	deleterious	0,68	low_impact	-1,88	medium_impact	-0,34	high_impact	2,11	0,74	0,9	2,73	6,62	P	0,57	P	0,7	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7325	7325	A	T	MI.4926	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1422	474	E	D	gaA/gaT	6,98	1	0	probably_damaging	0,94	neutral	0,1	neutral	2,83	deleterious	-3,84	neutral	-0,84	medium_impact	3,48	damaging	0,5	damaging	0,16	deleterious	3,9	23,5	0,32	0,55	neutral	0,22	disease	0,77	neutral	0,25	neutral	0,48	0	neutral	0,98	neutral	0,08	deleterious	1	deleterious	0,68	low_impact	-1,88	medium_impact	-0,34	high_impact	2,11	0,74	0,9	2,73	6,62	P	0,59	P	0,7	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7326	7326	G	C	MI.4927	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1423	475	A	P	Gcc/Ccc	-0,17	0,57	0	probably_damaging	1	deleterious	0,01	neutral	2,88	neutral	-2,3	neutral	-0,94	high_impact	4,32	damaging	0,48	damaging	0,07	deleterious	4,01	23,6	0,11	0,55	disease	0,55	disease	0,94	disease	0,65	disease	0,84	7	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,58	medium_impact	-0,92	high_impact	2,89	0,86	0,9	3,9	7,29	N	0,39	N	0,85	disease_causing	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7326	7326	G	A	MI.4928	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1423	475	A	T	Gcc/Acc	-0,17	0,57	0	probably_damaging	0,99	deleterious	0,01	neutral	3,08	neutral	-0,91	neutral	-0,39	medium_impact	3,07	damaging	0,49	damaging	0,06	deleterious	3,37	22,9	0,38	0,55	neutral	0,27	disease	0,69	neutral	0,18	neutral	0,48	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,71	low_impact	-2,64	medium_impact	-0,92	medium_impact	1,74	0,77	0,9	3,9	7,29	N	0,4	N	0,23	disease_causing	0,95	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7326	7326	G	T	MI.4929	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1423	475	A	S	Gcc/Tcc	-0,17	0,57	0	probably_damaging	0,99	neutral	0,76	neutral	3,15	neutral	3,69	neutral	0,39	low_impact	1,46	damaging	0,54	damaging	0,11	neutral	1,55	13,58	0,39	0,55	neutral	0,19	neutral	0,23	neutral	0,14	neutral	0,43	1	deleterious	0,99	neutral	0,39	neutral	-2	deleterious	0,64	low_impact	-2,64	medium_impact	0,47	medium_impact	0,25	0,79	0,9	3,9	7,29	N	0,33	N	0,61	disease_causing	0,88	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8758	8758	T	A	MI.493	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	232	78	F	I	Ttt/Att	-8,2	0	0	probably_damaging	0,99	neutral	0,11	neutral	4,13	deleterious	-3,1	deleterious	-5,26	medium_impact	2,48	neutral	0,9	damaging	0,2	deleterious	4,26	23,9	0,24	0,65	disease	0,74	disease	0,82	disease	0,61	disease	0,59	2	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,8	low_impact	-2,65	medium_impact	-0,22	medium_impact	1,03	0,57	0,9	49,56	8,89	N	0,37	N	0,94	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7327	7327	C	A	MI.4930	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1424	475	A	D	gCc/gAc	7,21	1	0	probably_damaging	1	deleterious	0	neutral	2,86	neutral	-1,57	neutral	-0,79	high_impact	4,32	damaging	0,5	damaging	0,05	deleterious	4,84	24,8	0,19	0,55	disease	0,5	disease	0,94	disease	0,64	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,58	low_impact	-1,48	high_impact	2,89	0,68	0,9	3,9	7,29	P	0,49	N	0,89	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7327	7327	C	G	MI.4931	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1424	475	A	G	gCc/gGc	7,21	1	0	probably_damaging	0,97	neutral	0,08	neutral	2,91	neutral	-0,62	neutral	-0,51	medium_impact	2,96	damaging	0,5	damaging	0,11	deleterious	4,08	23,7	0,26	0,55	neutral	0,37	disease	0,8	neutral	0,21	neutral	0,48	0	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,72	low_impact	-2,18	medium_impact	-0,4	medium_impact	1,63	0,84	0,9	3,9	7,29	P	0,54	P	0,56	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7327	7327	C	T	MI.4932	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1424	475	A	V	gCc/gTc	7,21	1	0	probably_damaging	0,99	deleterious	0	neutral	2,9	neutral	-1,75	neutral	-1,08	high_impact	4,32	damaging	0,5	damaging	0,06	deleterious	4,58	24,4	0,28	0,55	neutral	0,27	disease	0,87	disease	0,51	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,64	low_impact	-1,48	high_impact	2,89	0,76	0,9	3,9	7,29	P	0,49	N	0,75	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7329	7329	T	A	MI.4933	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1426	476	F	I	Ttc/Atc	-7,09	0	0	benign	0,1	neutral	0,12	neutral	3,07	neutral	0,37	neutral	-0,14	medium_impact	2,75	neutral	0,66	neutral	0,65	deleterious	3,44	23	0,28	0,55	neutral	0,33	disease	0,87	neutral	0,26	neutral	0,49	0	neutral	0,87	deleterious	0,51	neutral	-3	neutral	0,27	medium_impact	0,14	medium_impact	-0,29	medium_impact	1,44	0,52	0,9	5,07	8,7	N	0,48	N	0,87	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7329	7329	T	G	MI.4934	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1426	476	F	V	Ttc/Gtc	-7,09	0	0	benign	0,29	neutral	0,07	neutral	3,01	neutral	0,28	neutral	-0,3	high_impact	3,73	neutral	0,68	neutral	0,5	deleterious	4,29	24	0,3	0,55	neutral	0,27	disease	0,9	neutral	0,31	disease	0,7	4	neutral	0,92	neutral	0,39	neutral	-2	neutral	0,28	medium_impact	-0,39	medium_impact	-0,43	high_impact	2,35	0,43	0,9	5,07	8,7	N	0,49	N	0,84	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7329	7329	T	C	MI.4935	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1426	476	F	L	Ttc/Ctc	-7,09	0	0	benign	0	neutral	0,3	neutral	3,18	neutral	1,94	neutral	0,12	low_impact	0,88	neutral	0,71	neutral	0,92	deleterious	2,27	17,98	0,44	0,55	neutral	0,16	disease	0,55	neutral	0,16	neutral	0,43	2	neutral	0,7	deleterious	0,65	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	-0,01	medium_impact	-0,29	0,44	0,9	5,07	8,7	N	0,54	P	0,81	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7330	7330	T	A	MI.4936	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1427	476	F	Y	tTc/tAc	5,83	1	0	benign	0,33	neutral	0,05	neutral	2,93	neutral	-1,83	neutral	-0,48	high_impact	3,93	neutral	0,67	neutral	0,46	deleterious	4,35	24,1	0,45	0,55	neutral	0,46	disease	0,82	neutral	0,28	disease	0,52	0	neutral	0,94	neutral	0,36	neutral	-2	deleterious	0,44	medium_impact	-0,47	medium_impact	-0,52	high_impact	2,53	0,64	0,9	5,07	8,7	P	0,6	P	0,58	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7330	7330	T	G	MI.4937	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1427	476	F	C	tTc/tGc	5,83	1	0	probably_damaging	0,94	neutral	0,05	neutral	2,89	neutral	-2,65	neutral	-0,9	high_impact	4,28	neutral	0,68	neutral	0,47	deleterious	4,28	24	0,26	0,55	disease	0,66	disease	0,9	neutral	0,46	disease	0,75	5	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,73	low_impact	-1,88	medium_impact	-0,52	high_impact	2,85	0,27	0,9	5,07	8,7	P	0,57	P	0,91	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7330	7330	T	C	MI.4938	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1427	476	F	S	tTc/tCc	5,83	1	0	possibly_damaging	0,76	deleterious	0	neutral	2,92	neutral	-1,38	neutral	-0,98	high_impact	3,93	neutral	0,74	neutral	0,51	deleterious	4,38	24,1	0,35	0,55	neutral	0,29	disease	0,87	disease	0,59	disease	0,74	5	deleterious	1	neutral	0,12	deleterious	5	deleterious	0,62	low_impact	-1,23	low_impact	-1,48	high_impact	2,53	0,49	0,9	5,07	8,7	P	0,55	P	0,85	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7331	7331	C	G	MI.4939	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1428	476	F	L	ttC/ttG	7,44	1	0	benign	0	neutral	0,3	neutral	3,18	neutral	1,94	neutral	0,12	low_impact	0,88	neutral	0,71	neutral	0,92	deleterious	2,56	19,88	0,44	0,55	neutral	0,16	disease	0,55	neutral	0,16	neutral	0,43	2	neutral	0,7	deleterious	0,65	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	-0,01	medium_impact	-0,29	0,44	0,9	5,07	8,7	P	0,62	P	0,81	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8758	8758	T	C	MI.494	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	232	78	F	L	Ttt/Ctt	-8,2	0	0	probably_damaging	0,98	neutral	0,52	neutral	4,21	neutral	-2,28	deleterious	-5,21	low_impact	1,2	neutral	0,84	neutral	0,29	deleterious	2,82	21,5	0,33	0,65	disease	0,57	disease	0,63	neutral	0,47	neutral	0,49	0	neutral	0,98	neutral	0,27	neutral	-2	deleterious	0,74	low_impact	-2,36	medium_impact	0,31	medium_impact	-0,07	0,55	0,9	49,56	8,89	N	0,23	N	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7331	7331	C	A	MI.4940	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1428	476	F	L	ttC/ttA	7,44	1	0	benign	0	neutral	0,3	neutral	3,18	neutral	1,94	neutral	0,12	low_impact	0,88	neutral	0,71	neutral	0,92	deleterious	2,89	21,8	0,44	0,55	neutral	0,16	disease	0,55	neutral	0,16	neutral	0,43	2	neutral	0,7	deleterious	0,65	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	-0,01	medium_impact	-0,29	0,44	0,9	5,07	8,7	P	0,62	P	0,81	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7332	7332	G	T	MI.4941	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1429	477	A	S	Gct/Tct	-3,4	0	0	benign	0,01	neutral	0,6	neutral	3	neutral	1,9	neutral	-0,07	neutral_impact	-0,1	neutral	0,65	neutral	0,38	neutral	-0,39	0,4	0,3	0,55	neutral	0,25	neutral	0,29	neutral	0,12	neutral	0,44	1	neutral	0,39	deleterious	0,8	neutral	-6	neutral	0,13	medium_impact	1,12	medium_impact	0,29	low_impact	-1,19	0,61	0,9	9,75	25,17	N	0,41	N	0,61	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7332	7332	G	A	MI.4942	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1429	477	A	T	Gct/Act	-3,4	0	0	benign	0,13	neutral	0,52	neutral	2,98	neutral	-1,06	neutral	0,07	low_impact	0,94	neutral	0,65	neutral	0,74	deleterious	0,72	8,93	0,4	0,55	neutral	0,26	neutral	0,3	neutral	0,12	neutral	0,44	1	neutral	0,39	deleterious	0,7	neutral	-6	neutral	0,21	medium_impact	0,02	medium_impact	0,21	medium_impact	-0,23	0,56	0,9	9,75	25,17	N	0,48	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7332	7332	G	C	MI.4943	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1429	477	A	P	Gct/Cct	-3,4	0	0	possibly_damaging	0,9	neutral	0,2	neutral	2,94	neutral	-2,75	neutral	-0,7	medium_impact	3,47	damaging	0,6	damaging	0,13	deleterious	3,81	23,4	0,25	0,55	disease	0,55	disease	0,84	disease	0,57	disease	0,8	6	neutral	0,93	neutral	0,15	NA	0	deleterious	0,71	low_impact	-1,65	medium_impact	-0,14	high_impact	2,11	0,64	0,9	9,75	25,17	N	0,32	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7333	7333	C	G	MI.4944	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1430	477	A	G	gCt/gGt	0,29	0,04	0	benign	0,04	neutral	0,31	neutral	2,96	neutral	-2,14	neutral	-0,8	medium_impact	3,12	neutral	0,65	damaging	0,17	neutral	1,18	11,64	0,3	0,55	neutral	0,47	disease	0,55	neutral	0,28	neutral	0,47	1	neutral	0,67	deleterious	0,64	neutral	-3	neutral	0,18	medium_impact	0,54	medium_impact	0	medium_impact	1,78	0,55	0,9	9,75	25,17	N	0,43	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7333	7333	C	T	MI.4945	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1430	477	A	V	gCt/gTt	0,29	0,04	0	benign	0,11	neutral	0,62	neutral	3,05	neutral	0,47	neutral	0,29	low_impact	1,44	neutral	0,63	damaging	0,23	deleterious	0,57	7,94	0,35	0,55	neutral	0,24	neutral	0,42	neutral	0,12	neutral	0,45	1	neutral	0,28	deleterious	0,76	neutral	-6	neutral	0,38	medium_impact	0,1	medium_impact	0,31	medium_impact	0,23	0,46	0,9	9,75	25,17	N	0,38	N	0,75	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7333	7333	C	A	MI.4946	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1430	477	A	D	gCt/gAt	0,29	0,04	0	possibly_damaging	0,74	neutral	0,2	neutral	2,92	neutral	-1,66	neutral	-0,73	medium_impact	3,47	neutral	0,62	damaging	0,12	deleterious	4,5	24,3	0,25	0,55	neutral	0,4	disease	0,81	neutral	0,5	disease	0,7	4	neutral	0,85	neutral	0,23	NA	0	deleterious	0,46	low_impact	-1,18	medium_impact	-0,14	high_impact	2,11	0,48	0,9	9,75	25,17	N	0,39	N	0,89	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7335	7335	T	C	MI.4947	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1432	478	S	P	Tcg/Ccg	-4,78	0	0	benign	0,38	deleterious	0,02	neutral	2,83	deleterious	-3,53	neutral	-1,07	high_impact	4	damaging	0,51	neutral	0,33	deleterious	3,75	23,3	0,26	0,55	neutral	0,28	disease	0,9	disease	0,64	disease	0,77	5	neutral	0,98	neutral	0,32	deleterious	2	deleterious	0,62	medium_impact	-0,56	medium_impact	-0,75	high_impact	2,59	0,4	0,9	10,92	10,75	N	0,39	N	0,91	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7335	7335	T	A	MI.4948	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1432	478	S	T	Tcg/Acg	-4,78	0	0	benign	0,03	neutral	0,18	neutral	2,88	neutral	-0,54	neutral	-0,31	medium_impact	2,27	neutral	0,67	neutral	0,61	deleterious	0,84	9,71	0,45	0,55	neutral	0,35	neutral	0,49	neutral	0,2	neutral	0,45	1	neutral	0,81	deleterious	0,58	neutral	-3	neutral	0,16	medium_impact	0,66	medium_impact	-0,17	medium_impact	1	0,81	0,9	10,92	10,75	P	0,53	P	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7335	7335	T	G	MI.4949	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1432	478	S	A	Tcg/Gcg	-4,78	0	0	benign	0,03	neutral	0,63	neutral	2,91	neutral	-1,74	neutral	-0,56	low_impact	1,39	neutral	0,75	neutral	0,86	deleterious	0,56	7,89	0,43	0,55	neutral	0,22	neutral	0,49	neutral	0,37	neutral	0,46	1	neutral	0,32	deleterious	0,8	neutral	-6	neutral	0,14	medium_impact	0,66	medium_impact	0,32	medium_impact	0,18	0,63	0,9	10,92	10,75	N	0,32	N	0,33	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8758	8758	T	G	MI.495	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	232	78	F	V	Ttt/Gtt	-8,2	0	0	probably_damaging	0,99	neutral	0,27	neutral	4,22	neutral	-2,89	deleterious	-6,17	medium_impact	2,63	neutral	0,84	damaging	0,19	deleterious	3,86	23,5	0,21	0,65	disease	0,61	disease	0,84	disease	0,67	disease	0,57	1	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,78	low_impact	-2,65	medium_impact	0,05	medium_impact	1,16	0,59	0,9	49,56	8,89	N	0,27	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7336	7336	C	G	MI.4950	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1433	478	S	W	tCg/tGg	3,29	1	0	probably_damaging	0,97	deleterious	0,04	neutral	2,82	deleterious	-5,96	neutral	-1,5	high_impact	4	neutral	0,66	neutral	0,41	deleterious	4,48	24,2	0,24	0,55	disease	0,59	disease	0,92	disease	0,59	disease	0,77	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,78	low_impact	-2,18	medium_impact	-0,58	high_impact	2,59	0,45	0,9	10,92	10,75	N	0,4	N	0,94	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7336	7336	C	T	MI.4951	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1433	478	S	L	tCg/tTg	3,29	1	0	benign	0,04	neutral	0,14	neutral	2,92	neutral	-2,69	neutral	-1,09	medium_impact	3,06	neutral	0,68	neutral	0,41	deleterious	2,81	21,4	0,36	0,55	neutral	0,32	disease	0,81	neutral	0,41	disease	0,55	1	neutral	0,85	deleterious	0,55	neutral	-3	neutral	0,2	medium_impact	0,54	medium_impact	-0,25	medium_impact	1,73	0,78	0,9	10,92	10,75	P	0,57	P	0,91	disease_causing	0,94	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7338	7338	A	G	MI.4952	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1435	479	K	E	Aag/Gag	-5,47	0	0	probably_damaging	0,99	neutral	0,15	neutral	2,89	deleterious	-3,9	neutral	-0,23	high_impact	3,77	damaging	0,53	damaging	0,11	deleterious	4,08	23,7	0,48	0,55	neutral	0,3	disease	0,75	neutral	0,38	disease	0,53	1	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,74	low_impact	-2,64	medium_impact	-0,23	high_impact	2,38	0,68	0,9	NA	NA	N	0,39	N	0,75	polymorphism	0,97	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7338	7338	A	C	MI.4953	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1435	479	K	Q	Aag/Cag	-5,47	0	0	probably_damaging	0,99	neutral	0,26	neutral	2,94	deleterious	-4,09	neutral	0,18	low_impact	1,72	damaging	0,55	damaging	0,1	neutral	1,6	13,87	0,53	0,6	neutral	0,35	neutral	0,32	neutral	0,12	neutral	0,47	1	deleterious	0,99	neutral	0,14	neutral	-2	deleterious	0,68	low_impact	-2,64	medium_impact	-0,06	medium_impact	0,49	0,82	0,9	NA	NA	N	0,48	N	0,66	polymorphism	0,98	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7339	7339	A	C	MI.4954	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1436	479	K	T	aAg/aCg	8,59	1	0	probably_damaging	1	deleterious	0,03	neutral	2,88	deleterious	-4,6	neutral	-0,64	high_impact	3,91	damaging	0,52	damaging	0,12	deleterious	2,86	21,7	0,28	0,55	neutral	0,46	disease	0,62	neutral	0,35	disease	0,52	0	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-3,58	medium_impact	-0,65	high_impact	2,51	0,66	0,9	NA	NA	P	0,51	P	0,77	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7339	7339	A	T	MI.4955	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1436	479	K	M	aAg/aTg	8,59	1	0	probably_damaging	1	deleterious	0	neutral	2,85	deleterious	-6,18	neutral	-0,58	medium_impact	2,98	damaging	0,51	damaging	0,1	deleterious	4,19	23,8	0,28	0,55	disease	0,73	disease	0,56	neutral	0,22	disease	0,52	0	deleterious	1	neutral	0	deleterious	5	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	medium_impact	1,65	0,51	0,9	NA	NA	P	0,49	N	0,89	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7340	7340	G	T	MI.4956	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1437	479	K	N	aaG/aaT	8,59	1	0	probably_damaging	1	neutral	0,14	neutral	2,89	deleterious	-4,53	neutral	-0,36	medium_impact	2,51	damaging	0,51	damaging	0,08	deleterious	2,87	21,7	0,6	0,65	neutral	0,42	disease	0,5	neutral	0,2	neutral	0,44	1	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,72	low_impact	-3,58	medium_impact	-0,25	medium_impact	1,22	0,78	0,9	NA	NA	P	0,55	P	0,77	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7340	7340	G	C	MI.4957	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1437	479	K	N	aaG/aaC	8,59	1	0	probably_damaging	1	neutral	0,14	neutral	2,89	deleterious	-4,53	neutral	-0,36	medium_impact	2,51	damaging	0,51	damaging	0,08	deleterious	2,76	21,1	0,6	0,65	neutral	0,42	disease	0,5	neutral	0,2	neutral	0,44	1	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,72	low_impact	-3,58	medium_impact	-0,25	medium_impact	1,22	0,78	0,9	NA	NA	P	0,55	P	0,77	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7341	7341	C	T	MI.4958	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1438	480	R	W	Cga/Tga	0,75	0,99	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-9	neutral	-2,33	high_impact	4,78	neutral	0,62	damaging	0,19	deleterious	5,33	25,8	0,21	0,55	disease	0,87	disease	0,88	disease	0,6	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,32	0,73	0,9	NA	NA	P	0,65	P	1	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7341	7341	C	G	MI.4959	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1438	480	R	G	Cga/Gga	0,75	0,99	0	probably_damaging	0,98	deleterious	0	neutral	2,72	deleterious	-6,73	neutral	-2,02	high_impact	4,78	damaging	0,45	neutral	0,35	deleterious	4,35	24,1	0,3	0,55	neutral	0,31	disease	0,81	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,75	low_impact	-2,35	low_impact	-1,48	high_impact	3,32	0,52	0,9	NA	NA	P	0,64	P	0,91	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8759	8759	T	C	MI.496	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	233	78	F	S	tTt/tCt	0,82	0,32	0	probably_damaging	0,99	deleterious	0	neutral	4,09	deleterious	-4,16	deleterious	-7,11	medium_impact	3,12	neutral	0,83	damaging	0,21	deleterious	4,05	23,7	0,18	0,65	disease	0,84	disease	0,85	disease	0,65	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-2,65	low_impact	-1,4	medium_impact	1,58	0,52	0,9	49,56	8,89	N	0,29	N	0,99	disease_causing	0,91	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7342	7342	G	A	MI.4960	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1439	480	R	Q	cGa/cAa	3,52	1	0	probably_damaging	0,96	deleterious	0	neutral	2,68	deleterious	-4,8	neutral	-1,07	high_impact	4,23	damaging	0,58	damaging	0,23	deleterious	4,61	24,4	0,38	0,55	neutral	0,36	disease	0,77	disease	0,59	disease	0,56	1	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,75	low_impact	-2,06	low_impact	-1,48	high_impact	2,81	0,77	0,9	NA	NA	P	0,51	P	0,99	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7342	7342	G	C	MI.4961	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1439	480	R	P	cGa/cCa	3,52	1	0	probably_damaging	0,99	deleterious	0	neutral	2,71	deleterious	-7,14	neutral	-1,98	high_impact	4,78	damaging	0,52	damaging	0,23	deleterious	4,41	24,1	0,18	0,55	neutral	0,5	disease	0,89	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,64	low_impact	-1,48	high_impact	3,32	0,54	0,9	NA	NA	P	0,67	P	0,99	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7342	7342	G	T	MI.4962	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1439	480	R	L	cGa/cTa	3,52	1	0	probably_damaging	0,96	deleterious	0	neutral	2,66	deleterious	-6,24	neutral	-2,03	high_impact	4,78	damaging	0,57	damaging	0,28	deleterious	4,52	24,3	0,28	0,55	neutral	0,45	disease	0,88	disease	0,69	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-2,06	low_impact	-1,48	high_impact	3,32	0,46	0,9	NA	NA	P	0,66	P	0,98	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7344	7344	A	C	MI.4963	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1441	481	K	Q	Aaa/Caa	-1,09	0	0	benign	0,17	neutral	0,45	neutral	2,89	deleterious	-4,09	neutral	-0,06	medium_impact	2,01	neutral	0,71	neutral	0,46	neutral	1,62	13,96	0,49	0,55	neutral	0,34	neutral	0,31	neutral	0,17	neutral	0,46	1	neutral	0,46	deleterious	0,64	neutral	-3	neutral	0,27	medium_impact	-0,11	medium_impact	0,14	medium_impact	0,76	0,76	0,9	14,04	56,76	N	0,53	P	0,29	polymorphism	0,94	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7344	7344	A	G	MI.4964	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1441	481	K	E	Aaa/Gaa	-1,09	0	0	benign	0,01	neutral	1	neutral	2,91	deleterious	-3,9	neutral	-0,27	low_impact	0,94	neutral	0,7	neutral	0,92	neutral	1,5	13,33	0,46	0,55	neutral	0,22	disease	0,53	neutral	0,22	neutral	0,44	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,16	medium_impact	1,12	high_impact	1,86	medium_impact	-0,23	0,8	0,9	14,04	56,76	N	0,33	N	0	polymorphism	0,9	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7345	7345	A	C	MI.4965	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1442	481	K	T	aAa/aCa	4,9	1	0	benign	0,23	neutral	0,46	neutral	2,9	deleterious	-4,6	neutral	-0,38	low_impact	1,58	neutral	0,77	neutral	0,63	neutral	1,63	13,99	0,3	0,55	neutral	0,34	neutral	0,33	neutral	0,21	neutral	0,46	1	neutral	0,44	deleterious	0,62	neutral	-6	neutral	0,35	medium_impact	-0,26	medium_impact	0,15	medium_impact	0,36	0,63	0,9	14,04	56,76	P	0,55	P	0,46	disease_causing	0,59	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7345	7345	A	T	MI.4966	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1442	481	K	M	aAa/aTa	4,9	1	0	possibly_damaging	0,82	neutral	0,1	neutral	2,88	deleterious	-6,18	neutral	-0,33	low_impact	1,89	neutral	0,73	neutral	0,44	deleterious	2,58	19,95	0,27	0,55	disease	0,67	neutral	0,27	neutral	0,21	disease	0,56	1	neutral	0,94	neutral	0,14	neutral	-3	deleterious	0,65	low_impact	-1,38	medium_impact	-0,34	medium_impact	0,65	0,52	0,9	14,04	56,76	P	0,59	P	0,62	disease_causing	0,76	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7346	7346	A	C	MI.4967	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1443	481	K	N	aaA/aaC	8,59	1	0	benign	0,23	neutral	0,38	neutral	2,86	deleterious	-4,53	neutral	-0,45	medium_impact	2,6	neutral	0,73	neutral	0,41	deleterious	2,08	16,74	0,56	0,6	neutral	0,33	neutral	0,41	neutral	0,36	neutral	0,46	1	neutral	0,54	deleterious	0,58	neutral	-3	neutral	0,35	medium_impact	-0,26	medium_impact	0,07	medium_impact	1,3	0,81	0,9	14,04	56,76	P	0,62	P	0,4	disease_causing	0,97	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7346	7346	A	T	MI.4968	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1443	481	K	N	aaA/aaT	8,59	1	0	benign	0,23	neutral	0,38	neutral	2,86	deleterious	-4,53	neutral	-0,45	medium_impact	2,6	neutral	0,73	neutral	0,41	deleterious	2,32	18,28	0,56	0,6	neutral	0,33	neutral	0,41	neutral	0,36	neutral	0,46	1	neutral	0,54	deleterious	0,58	neutral	-3	neutral	0,35	medium_impact	-0,26	medium_impact	0,07	medium_impact	1,3	0,81	0,9	14,04	56,76	P	0,62	P	0,4	disease_causing	0,97	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7347	7347	G	C	MI.4969	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1444	482	V	L	Gtc/Ctc	0,98	1	0	benign	0	neutral	0,26	neutral	2,93	neutral	-0,36	neutral	-0,39	medium_impact	2,19	neutral	0,66	neutral	0,65	deleterious	0,47	7,18	0,44	0,55	neutral	0,13	neutral	0,39	neutral	0,16	neutral	0,44	1	neutral	0,74	deleterious	0,63	neutral	-3	neutral	0,09	high_impact	2,07	medium_impact	-0,06	medium_impact	0,92	0,7	0,9	9,94	12,51	P	0,58	P	0,55	disease_causing	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8759	8759	T	G	MI.497	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	233	78	F	C	tTt/tGt	0,82	0,32	0	probably_damaging	1	deleterious	0,04	neutral	4,07	deleterious	-5,66	deleterious	-7,15	medium_impact	3,25	neutral	0,84	damaging	0,16	deleterious	3,95	23,6	0,17	0,65	disease	0,92	disease	0,88	disease	0,68	disease	0,82	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,83	low_impact	-3,6	medium_impact	-0,49	medium_impact	1,69	0,39	0,9	49,56	8,89	N	0,3	N	1	disease_causing	0,94	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7347	7347	G	T	MI.4970	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1444	482	V	F	Gtc/Ttc	0,98	1	0	benign	0,27	neutral	0,27	neutral	2,82	neutral	-2,66	neutral	-0,83	medium_impact	2,67	neutral	0,64	neutral	0,53	neutral	1,04	10,91	0,24	0,55	neutral	0,4	disease	0,64	neutral	0,21	neutral	0,44	1	neutral	0,67	deleterious	0,5	neutral	-3	neutral	0,34	medium_impact	-0,35	medium_impact	-0,05	medium_impact	1,37	0,65	0,9	9,94	12,51	P	0,53	P	0,84	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7347	7347	G	A	MI.4971	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1444	482	V	I	Gtc/Atc	0,98	1	0	benign	0	neutral	0,27	neutral	2,91	neutral	1,45	neutral	0,03	neutral_impact	0,53	neutral	0,77	neutral	0,88	deleterious	0,14	4,03	0,59	0,65	neutral	0,2	neutral	0,19	neutral	0,16	neutral	0,36	3	neutral	0,73	deleterious	0,64	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	-0,05	medium_impact	-0,61	0,79	0,9	9,94	12,51	P	0,57	P	0,18	disease_causing	0,96	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7348	7348	T	G	MI.4972	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1445	482	V	G	gTc/gGc	5,13	1	0	benign	0,16	deleterious	0,03	neutral	2,83	deleterious	-3,89	neutral	-1,61	medium_impact	3,13	neutral	0,65	neutral	0,56	deleterious	2,17	17,32	0,21	0,55	neutral	0,49	disease	0,64	neutral	0,46	neutral	0,49	0	neutral	0,97	neutral	0,44	deleterious	1	neutral	0,28	medium_impact	-0,08	medium_impact	-0,65	medium_impact	1,79	0,56	0,9	9,94	12,51	P	0,56	P	0,72	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7348	7348	T	A	MI.4973	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1445	482	V	D	gTc/gAc	5,13	1	0	benign	0,33	deleterious	0,01	neutral	2,79	deleterious	-4,34	neutral	-1,47	high_impact	3,83	neutral	0,65	neutral	0,42	deleterious	3,04	22,4	0,17	0,55	disease	0,54	disease	0,8	disease	0,52	disease	0,71	4	deleterious	0,99	neutral	0,34	deleterious	2	deleterious	0,49	medium_impact	-0,47	medium_impact	-0,92	high_impact	2,44	0,54	0,9	9,94	12,51	P	0,5	N	0,83	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7348	7348	T	C	MI.4974	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1445	482	V	A	gTc/gCc	5,13	1	0	benign	0,01	neutral	0,07	neutral	2,92	neutral	-2,06	neutral	-0,81	low_impact	1,36	neutral	0,67	neutral	0,62	deleterious	0,66	8,57	0,43	0,55	neutral	0,27	neutral	0,32	neutral	0,38	neutral	0,44	1	neutral	0,93	deleterious	0,53	neutral	-6	neutral	0,13	medium_impact	1,12	medium_impact	-0,43	medium_impact	0,16	0,4	0,9	9,94	12,51	P	0,66	P	0,47	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7350	7350	C	G	MI.4975	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1447	483	L	V	Cta/Gta	-20	0	0	benign	0,01	neutral	0,12	neutral	2,93	deleterious	-3,87	neutral	-0,13	low_impact	1,49	neutral	0,73	neutral	0,84	deleterious	0,12	3,82	0,6	0,65	neutral	0,17	neutral	0,32	neutral	0,12	neutral	0,45	1	neutral	0,88	deleterious	0,56	neutral	-6	neutral	0,1	medium_impact	1,12	medium_impact	-0,29	medium_impact	0,28	0,55	0,9	7,6	20,3	N	0,58	P	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7350	7350	C	A	MI.4976	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1447	483	L	M	Cta/Ata	-20	0	0	benign	0	neutral	0,12	neutral	2,86	deleterious	-4,68	neutral	-0,11	low_impact	1,4	neutral	0,73	neutral	0,96	deleterious	0,49	7,32	0,33	0,55	neutral	0,31	neutral	0,26	neutral	0,14	neutral	0,44	1	neutral	0,88	deleterious	0,56	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	-0,29	medium_impact	0,19	0,75	0,9	7,6	20,3	P	0,58	P	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7351	7351	T	A	MI.4977	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1448	483	L	Q	cTa/cAa	-12,62	0	0	benign	0,06	neutral	0,05	neutral	2,85	deleterious	-7,38	neutral	-1,16	medium_impact	3,08	neutral	0,73	neutral	0,82	neutral	1,32	12,35	0,26	0,55	neutral	0,32	disease	0,69	neutral	0,22	disease	0,53	1	neutral	0,95	deleterious	0,5	neutral	-3	neutral	0,19	medium_impact	0,37	medium_impact	-0,52	medium_impact	1,75	0,59	0,9	7,6	20,3	N	0,46	N	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7351	7351	T	G	MI.4978	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1448	483	L	R	cTa/cGa	-12,62	0	0	benign	0,02	deleterious	0,02	neutral	2,89	deleterious	-7,35	neutral	-1,25	medium_impact	3,28	neutral	0,66	neutral	0,63	deleterious	2,43	19	0,35	0,55	neutral	0,2	disease	0,79	neutral	0,45	disease	0,64	3	neutral	0,98	deleterious	0,5	deleterious	1	neutral	0,2	medium_impact	0,83	medium_impact	-0,75	medium_impact	1,93	0,52	0,9	7,6	20,3	N	0,4	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7351	7351	T	C	MI.4979	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1448	483	L	P	cTa/cCa	-12,62	0	0	benign	0,21	deleterious	0,03	neutral	2,88	deleterious	-7,82	neutral	-1,35	medium_impact	3,42	neutral	0,73	neutral	0,84	deleterious	2,09	16,81	0,24	0,55	neutral	0,48	disease	0,81	neutral	0,4	disease	0,58	2	neutral	0,97	neutral	0,41	deleterious	1	neutral	0,38	medium_impact	-0,22	medium_impact	-0,65	high_impact	2,06	0,37	0,9	7,6	20,3	N	0,37	N	0,05	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8759	8759	T	A	MI.498	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	233	78	F	Y	tTt/tAt	0,82	0,32	0	probably_damaging	0,98	neutral	0,14	neutral	4,25	deleterious	-3,53	deleterious	-2,63	medium_impact	2,02	neutral	0,89	damaging	0,26	deleterious	2,88	21,8	0,27	0,65	disease	0,81	disease	0,72	neutral	0,49	disease	0,62	2	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,8	low_impact	-2,36	medium_impact	-0,15	medium_impact	0,63	0,65	0,9	49,56	8,89	N	0,38	N	0,89	disease_causing	0,57	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7353	7353	A	C	MI.4980	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1450	484	M	L	Ata/Cta	-8,01	0	0	benign	0	neutral	0,62	neutral	3,1	neutral	2,26	neutral	-0,1	neutral_impact	0	neutral	0,79	neutral	0,93	deleterious	0,07	3,32	0,6	0,65	neutral	0,15	neutral	0,29	neutral	0,24	neutral	0,43	1	neutral	0,38	deleterious	0,81	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,31	low_impact	-1,1	0,4	0,9	16,57	30,87	N	0,34	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7353	7353	A	T	MI.4981	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1450	484	M	L	Ata/Tta	-8,01	0	0	benign	0	neutral	0,62	neutral	3,1	neutral	2,26	neutral	-0,1	neutral_impact	0	neutral	0,79	neutral	0,93	deleterious	0,18	4,43	0,6	0,65	neutral	0,15	neutral	0,29	neutral	0,24	neutral	0,43	1	neutral	0,38	deleterious	0,81	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,31	low_impact	-1,1	0,4	0,9	16,57	30,87	N	0,35	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7353	7353	A	G	MI.4982	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1450	484	M	V	Ata/Gta	-8,01	0	0	benign	0	neutral	0,45	neutral	3,06	neutral	1,02	neutral	-0,28	neutral_impact	0,34	neutral	0,84	neutral	0,96	neutral	-0,35	0,51	0,64	0,65	neutral	0,18	neutral	0,34	neutral	0,26	neutral	0,45	1	neutral	0,55	deleterious	0,73	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,14	medium_impact	-0,79	0,29	0,9	16,57	30,87	N	0,37	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7354	7354	T	A	MI.4983	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1451	484	M	K	aTa/aAa	-2,48	0	0	benign	0,01	neutral	0,26	neutral	3,01	neutral	-0,86	neutral	-0,47	neutral_impact	0,41	neutral	0,77	neutral	0,74	neutral	1,27	12,1	0,28	0,55	neutral	0,19	disease	0,6	neutral	0,36	neutral	0,49	0	neutral	0,74	deleterious	0,63	neutral	-6	neutral	0,12	medium_impact	1,12	medium_impact	-0,06	medium_impact	-0,72	0,49	0,9	16,57	30,87	N	0,36	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7354	7354	T	C	MI.4984	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1451	484	M	T	aTa/aCa	-2,48	0	0	benign	0	neutral	0,42	neutral	3,04	neutral	-0,32	neutral	-0,27	neutral_impact	-0,34	neutral	0,78	neutral	0,99	neutral	-0,34	0,53	0,49	0,55	neutral	0,22	neutral	0,31	neutral	0,31	neutral	0,45	1	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,12	low_impact	-1,41	0,09	0,9	16,57	30,87	N	0,36	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7355	7355	A	C	MI.4985	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1452	484	M	I	atA/atC	-0,86	0	0	benign	0	neutral	0,41	neutral	3,03	neutral	1,06	neutral	-0,13	neutral_impact	0,52	neutral	0,81	neutral	0,86	deleterious	0,21	4,77	0,61	0,65	neutral	0,18	neutral	0,36	neutral	0,14	neutral	0,45	1	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,11	medium_impact	-0,62	0,35	0,9	16,57	30,87	N	0,5	N	0,13	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7355	7355	A	T	MI.4986	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1452	484	M	I	atA/atT	-0,86	0	0	benign	0	neutral	0,41	neutral	3,03	neutral	1,06	neutral	-0,13	neutral_impact	0,52	neutral	0,81	neutral	0,86	deleterious	0,44	6,99	0,61	0,65	neutral	0,18	neutral	0,36	neutral	0,14	neutral	0,45	1	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,11	medium_impact	-0,62	0,35	0,9	16,57	30,87	N	0,5	N	0,13	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7356	7356	G	C	MI.4987	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1453	485	V	L	Gta/Cta	-2,24	0	0	benign	0	neutral	0,33	neutral	3,02	neutral	0,79	neutral	-0,04	neutral_impact	0,48	neutral	0,71	neutral	0,61	neutral	-0,09	1,79	0,55	0,6	neutral	0,2	neutral	0,28	neutral	0,25	neutral	0,43	1	neutral	0,67	deleterious	0,67	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,02	medium_impact	-0,66	0,55	0,9	14,62	44,85	N	0,47	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7356	7356	G	A	MI.4988	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1453	485	V	M	Gta/Ata	-2,24	0	0	benign	0	neutral	0,11	neutral	2,98	neutral	1,83	neutral	0,18	neutral_impact	0,74	neutral	0,77	neutral	0,63	deleterious	0,58	8,02	0,46	0,55	neutral	0,46	neutral	0,23	neutral	0,17	neutral	0,44	1	neutral	0,89	deleterious	0,56	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	-0,31	medium_impact	-0,42	0,65	0,9	14,62	44,85	P	0,55	P	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7356	7356	G	T	MI.4989	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1453	485	V	L	Gta/Tta	-2,24	0	0	benign	0	neutral	0,33	neutral	3,02	neutral	0,79	neutral	-0,04	neutral_impact	0,48	neutral	0,71	neutral	0,61	deleterious	0,06	3,21	0,55	0,6	neutral	0,2	neutral	0,28	neutral	0,25	neutral	0,43	1	neutral	0,67	deleterious	0,67	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,02	medium_impact	-0,66	0,55	0,9	14,62	44,85	N	0,48	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8760	8760	T	A	MI.499	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	234	78	F	L	ttT/ttA	2,9	0,43	0	probably_damaging	0,98	neutral	0,52	neutral	4,21	neutral	-2,28	deleterious	-5,21	low_impact	1,2	neutral	0,84	neutral	0,29	deleterious	3,25	22,8	0,33	0,65	disease	0,57	disease	0,63	neutral	0,47	neutral	0,49	0	neutral	0,98	neutral	0,27	neutral	-2	deleterious	0,74	low_impact	-2,36	medium_impact	0,31	medium_impact	-0,07	0,55	0,9	49,56	8,89	N	0,29	N	0,89	disease_causing	0,93	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7357	7357	T	G	MI.4990	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1454	485	V	G	gTa/gGa	-0,17	0	0	benign	0,03	neutral	0,38	neutral	2,98	neutral	1,49	neutral	-0,11	low_impact	1,31	neutral	0,71	neutral	0,61	deleterious	0,65	8,47	0,23	0,55	neutral	0,18	neutral	0,41	neutral	0,42	neutral	0,44	1	neutral	0,6	deleterious	0,68	neutral	-6	neutral	0,12	medium_impact	0,66	medium_impact	0,07	medium_impact	0,11	0,47	0,9	14,62	44,85	N	0,46	N	0,7	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7357	7357	T	C	MI.4991	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1454	485	V	A	gTa/gCa	-0,17	0	0	benign	0	neutral	0,77	neutral	3,02	neutral	0,7	neutral	0,29	low_impact	1,05	neutral	0,77	neutral	0,7	deleterious	0,07	3,31	0,5	0,55	neutral	0,18	neutral	0,24	neutral	0,35	neutral	0,41	2	neutral	0,23	deleterious	0,89	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,48	medium_impact	-0,13	0,41	0,9	14,62	44,85	N	0,31	N	0,65	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7357	7357	T	A	MI.4992	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1454	485	V	E	gTa/gAa	-0,17	0	0	benign	0,03	neutral	1	neutral	3,06	neutral	-0,97	neutral	0,04	medium_impact	2,25	neutral	0,66	neutral	0,5	deleterious	1,85	15,29	0,2	0,55	neutral	0,18	disease	0,64	neutral	0,43	disease	0,52	0	neutral	0,03	deleterious	0,99	neutral	-3	neutral	0,16	medium_impact	0,66	high_impact	1,86	medium_impact	0,98	0,49	0,9	14,62	44,85	N	0,29	N	0,91	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7359	7359	G	C	MI.4993	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1456	486	E	Q	Gaa/Caa	-4,78	0	0	benign	0,29	neutral	0,34	neutral	2,99	neutral	0,11	neutral	0,07	medium_impact	2,19	neutral	0,71	neutral	0,39	neutral	-0,27	0,78	0,55	0,6	neutral	0,38	neutral	0,17	neutral	0,36	neutral	0,33	3	neutral	0,59	deleterious	0,53	neutral	-3	neutral	0,32	medium_impact	-0,39	medium_impact	0,03	medium_impact	0,92	0,68	0,9	7,02	40,53	N	0,44	N	0,51	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7359	7359	G	A	MI.4994	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1456	486	E	K	Gaa/Aaa	-4,78	0	0	benign	0,12	neutral	0,36	neutral	3,03	neutral	0,29	neutral	-0,14	low_impact	0,84	neutral	0,62	damaging	0,27	deleterious	0,64	8,44	0,29	0,55	neutral	0,31	neutral	0,28	neutral	0,44	neutral	0,42	2	neutral	0,58	deleterious	0,62	neutral	-6	neutral	0,19	medium_impact	0,06	medium_impact	0,05	medium_impact	-0,32	0,69	0,9	7,02	40,53	N	0,38	N	0,49	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7360	7360	A	T	MI.4995	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1457	486	E	V	gAa/gTa	3,52	1	0	benign	0,41	neutral	0,52	neutral	3,05	neutral	2,56	neutral	-0,1	medium_impact	2,25	neutral	0,66	neutral	0,29	deleterious	0,53	7,66	0,23	0,55	disease	0,57	neutral	0,32	neutral	0,41	disease	0,56	1	neutral	0,43	deleterious	0,56	neutral	-3	deleterious	0,44	medium_impact	-0,61	medium_impact	0,21	medium_impact	0,98	0,56	0,9	7,02	40,53	N	0,46	N	0,63	disease_causing	0,9	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7360	7360	A	G	MI.4996	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1457	486	E	G	gAa/gGa	3,52	1	0	benign	0,12	neutral	0,38	neutral	2,99	neutral	0,28	neutral	-0,64	medium_impact	2,33	neutral	0,67	neutral	0,3	deleterious	0,75	9,13	0,38	0,55	neutral	0,42	neutral	0,19	neutral	0,48	neutral	0,37	3	neutral	0,56	deleterious	0,63	neutral	-3	neutral	0,19	medium_impact	0,06	medium_impact	0,07	medium_impact	1,05	0,45	0,9	7,02	40,53	P	0,55	P	0,34	disease_causing	0,82	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7360	7360	A	C	MI.4997	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1457	486	E	A	gAa/gCa	3,52	1	0	benign	0,12	neutral	0,55	neutral	3,04	neutral	3,23	neutral	-0,17	medium_impact	1,98	neutral	0,71	neutral	0,35	neutral	-0,43	0,32	0,37	0,55	neutral	0,31	neutral	0,21	neutral	0,4	neutral	0,36	3	neutral	0,36	deleterious	0,72	neutral	-3	neutral	0,22	medium_impact	0,06	medium_impact	0,24	medium_impact	0,73	0,49	0,9	7,02	40,53	N	0,47	N	0,14	disease_causing	0,79	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7361	7361	A	C	MI.4998	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1458	486	E	D	gaA/gaC	6,75	1	0	benign	0,12	neutral	0,26	neutral	2,98	neutral	-0,86	neutral	-0,27	low_impact	1,22	neutral	0,71	neutral	0,91	deleterious	0,21	4,76	0,5	0,55	neutral	0,24	neutral	0,2	neutral	0,34	neutral	0,36	3	neutral	0,7	deleterious	0,57	neutral	-6	neutral	0,15	medium_impact	0,06	medium_impact	-0,06	medium_impact	0,03	0,75	0,9	7,02	40,53	P	0,68	P	0,01	disease_causing	0,52	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7361	7361	A	T	MI.4999	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1458	486	E	D	gaA/gaT	6,75	1	0	benign	0,12	neutral	0,26	neutral	2,98	neutral	-0,86	neutral	-0,27	low_impact	1,22	neutral	0,71	neutral	0,91	deleterious	0,34	6,04	0,5	0,55	neutral	0,24	neutral	0,2	neutral	0,34	neutral	0,36	3	neutral	0,7	deleterious	0,57	neutral	-6	neutral	0,15	medium_impact	0,06	medium_impact	-0,06	medium_impact	0,03	0,75	0,9	7,02	40,53	P	0,68	P	0,01	disease_causing	0,52	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8529	8529	G	T	MI.5	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	3	1	M	I	atG/atT	7,53	1	0	possibly_damaging	0,72	deleterious	0	neutral	4,58	neutral	0,17	deleterious	-3,33	NA	NA	neutral	0,68	damaging	0,12	deleterious	4,28	24	0,46	0,65	disease	0,77	neutral	0,44	disease	0,64	disease	0,61	2	deleterious	1	neutral	0,14	deleterious	3	deleterious	0,68	NA	NA	NA	NA	NA	NA	0,55	0,9	50	8,74	P	0,61	P	0,94	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8548	8548	T	G	MI.50	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	22	8	S	A	Tca/Gca	-0,1	0,83	0	benign	0,03	neutral	0,37	neutral	4,67	neutral	-0,28	neutral	-1,32	low_impact	1,84	neutral	0,82	neutral	0,56	neutral	1,55	13,58	0,4	0,65	disease	0,58	neutral	0,39	neutral	0,47	disease	0,61	2	neutral	0,61	deleterious	0,67	neutral	-6	neutral	0,23	medium_impact	0,68	medium_impact	0,16	medium_impact	0,48	0,57	0,9	21,24	17,86	N	0,32	N	0,27	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8760	8760	T	G	MI.500	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	234	78	F	L	ttT/ttG	2,9	0,43	0	probably_damaging	0,98	neutral	0,52	neutral	4,21	neutral	-2,28	deleterious	-5,21	low_impact	1,2	neutral	0,84	neutral	0,29	deleterious	3,12	22,5	0,33	0,65	disease	0,57	disease	0,63	neutral	0,47	neutral	0,49	0	neutral	0,98	neutral	0,27	neutral	-2	deleterious	0,74	low_impact	-2,36	medium_impact	0,31	medium_impact	-0,07	0,55	0,9	49,56	8,89	N	0,27	N	0,89	disease_causing	0,93	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7362	7362	G	A	MI.5000	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1459	487	E	K	Gaa/Aaa	-0,17	0	0	benign	0	neutral	0,28	neutral	3,04	neutral	3,9	neutral	-0,05	neutral_impact	-1,38	neutral	0,61	neutral	0,47	neutral	1,26	12,04	0,31	0,55	neutral	0,26	neutral	0,35	neutral	0,29	neutral	0,45	1	neutral	0,72	deleterious	0,64	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	-0,04	low_impact	-2,37	0,65	0,9	16,18	50,61	N	0,47	N	0,23	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7362	7362	G	C	MI.5001	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1459	487	E	Q	Gaa/Caa	-0,17	0	0	benign	0	neutral	0,3	neutral	3,01	neutral	-0,19	neutral	0,25	neutral_impact	-1,54	neutral	0,74	neutral	0,91	deleterious	-0,07	2	0,47	0,55	neutral	0,31	neutral	0,11	neutral	0,21	neutral	0,32	4	neutral	0,7	deleterious	0,65	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	-0,01	low_impact	-2,52	0,63	0,9	16,18	50,61	N	0,54	P	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7363	7363	A	G	MI.5002	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1460	487	E	G	gAa/gGa	-2,48	0	0	benign	0	neutral	0,34	neutral	3	neutral	-1,03	neutral	-0,33	neutral_impact	-0,5	neutral	0,68	neutral	0,76	deleterious	0,82	9,6	0,29	0,55	neutral	0,48	neutral	0,26	disease	0,51	neutral	0,44	1	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	0,03	low_impact	-1,56	0,47	0,9	16,18	50,61	N	0,42	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7363	7363	A	C	MI.5003	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1460	487	E	A	gAa/gCa	-2,48	0	0	benign	0	neutral	0,5	neutral	3,06	neutral	-0,34	neutral	-0,18	neutral_impact	-0,62	neutral	0,67	neutral	0,81	deleterious	-0,04	2,26	0,3	0,55	neutral	0,31	neutral	0,24	neutral	0,44	neutral	0,43	1	neutral	0,5	deleterious	0,75	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,19	low_impact	-1,67	0,49	0,9	16,18	50,61	N	0,4	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7363	7363	A	T	MI.5004	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1460	487	E	V	gAa/gTa	-2,48	0	0	benign	0	neutral	0,49	neutral	3,05	neutral	-1,13	neutral	-0,25	neutral_impact	0,7	neutral	0,64	neutral	0,69	deleterious	0,44	6,92	0,22	0,55	neutral	0,49	neutral	0,38	neutral	0,42	neutral	0,42	2	neutral	0,51	deleterious	0,75	neutral	-6	neutral	0,16	high_impact	2,07	medium_impact	0,18	medium_impact	-0,45	0,59	0,9	16,18	50,61	N	0,39	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7364	7364	A	C	MI.5005	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1461	487	E	D	gaA/gaC	4,67	0,66	0,01	benign	0	neutral	0,21	neutral	2,99	neutral	-0,62	neutral	-0,1	neutral_impact	0,34	damaging	0,58	neutral	0,44	deleterious	0,6	8,14	0,41	0,55	neutral	0,26	neutral	0,27	neutral	0,34	neutral	0,43	1	neutral	0,79	deleterious	0,61	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	-0,13	medium_impact	-0,79	0,7	0,9	16,18	50,61	N	0,49	N	0,24	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7364	7364	A	T	MI.5006	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1461	487	E	D	gaA/gaT	4,67	0,66	0,01	benign	0	neutral	0,21	neutral	2,99	neutral	-0,62	neutral	-0,1	neutral_impact	0,34	damaging	0,58	neutral	0,44	deleterious	0,7	8,81	0,41	0,55	neutral	0,26	neutral	0,27	neutral	0,34	neutral	0,43	1	neutral	0,79	deleterious	0,61	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	-0,13	medium_impact	-0,79	0,7	0,9	16,18	50,61	N	0,49	N	0,24	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7365	7365	C	A	MI.5007	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1462	488	P	T	Ccc/Acc	-3,63	0	0	benign	0	neutral	1	neutral	3,03	neutral	1,16	neutral	0,54	neutral_impact	-0,78	neutral	0,73	neutral	0,99	neutral	-0,14	1,47	0,38	0,55	neutral	0,35	neutral	0,12	neutral	0,22	neutral	0,29	4	neutral	0	deleterious	1	neutral	-6	neutral	0,08	high_impact	2,07	high_impact	1,86	low_impact	-1,82	0,57	0,9	15,79	41,36	N	0,36	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7365	7365	C	G	MI.5008	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1462	488	P	A	Ccc/Gcc	-3,63	0	0	benign	0,01	neutral	0,42	neutral	3,04	neutral	1,39	neutral	0,28	low_impact	1,21	neutral	0,78	neutral	0,91	neutral	-0,32	0,58	0,38	0,55	neutral	0,41	neutral	0,18	neutral	0,37	neutral	0,31	4	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,12	medium_impact	0,02	0,63	0,9	15,79	41,36	N	0,39	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7365	7365	C	T	MI.5009	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1462	488	P	S	Ccc/Tcc	-3,63	0	0	benign	0	neutral	0,45	neutral	3,02	neutral	2,96	neutral	0,33	neutral_impact	0,39	neutral	0,81	neutral	0,97	deleterious	0,35	6,19	0,42	0,55	neutral	0,46	neutral	0,18	neutral	0,21	neutral	0,3	4	neutral	0,55	deleterious	0,73	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,14	medium_impact	-0,74	0,31	0,9	15,79	41,36	N	0,42	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8761	8761	A	T	MI.501	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	235	79	I	F	Att/Ttt	-2,88	0	0	probably_damaging	0,99	deleterious	0	neutral	3,33	deleterious	-6,11	deleterious	-3	medium_impact	2,48	neutral	0,84	neutral	0,39	deleterious	3,63	23,2	0,27	0,65	disease	0,81	disease	0,79	disease	0,59	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,82	low_impact	-2,65	low_impact	-1,4	medium_impact	1,03	0,74	0,9	49,56	8,5	N	0,32	N	0,9	polymorphism	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7366	7366	C	G	MI.5010	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1463	488	P	R	cCc/cGc	0,52	0	0	benign	0,09	neutral	0,36	neutral	3,01	neutral	-0,04	neutral	0,11	low_impact	1,9	neutral	0,68	neutral	0,47	deleterious	0,57	7,95	0,3	0,55	disease	0,58	neutral	0,38	neutral	0,43	disease	0,61	2	neutral	0,59	deleterious	0,64	neutral	-6	neutral	0,19	medium_impact	0,19	medium_impact	0,05	medium_impact	0,66	0,51	0,9	15,79	41,36	N	0,47	N	0,38	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7366	7366	C	T	MI.5011	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1463	488	P	L	cCc/cTc	0,52	0	0	benign	0	neutral	0,46	neutral	3,13	neutral	4,48	neutral	0,87	neutral_impact	-0,57	neutral	0,72	neutral	0,8	neutral	-0,15	1,39	0,31	0,55	neutral	0,36	neutral	0,19	neutral	0,43	neutral	0,34	3	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,15	low_impact	-1,63	0,7	0,9	15,79	41,36	N	0,45	N	0,35	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7366	7366	C	A	MI.5012	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1463	488	P	H	cCc/cAc	0,52	0	0	benign	0,3	neutral	0,1	neutral	2,98	neutral	-0,7	neutral	-0,01	low_impact	1,9	neutral	0,72	neutral	0,49	neutral	1,31	12,32	0,36	0,55	disease	0,7	neutral	0,25	neutral	0,39	disease	0,56	1	neutral	0,88	neutral	0,4	neutral	-6	neutral	0,28	medium_impact	-0,41	medium_impact	-0,34	medium_impact	0,66	0,46	0,9	15,79	41,36	N	0,51	P	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7368	7368	T	C	MI.5013	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1465	489	S	P	Tcc/Ccc	-8,47	0	0	benign	0	neutral	0,45	neutral	2,91	deleterious	-3,51	neutral	-0,46	low_impact	1,05	neutral	0,79	neutral	0,77	deleterious	0,48	7,26	0,29	0,55	disease	0,52	disease	0,57	neutral	0,26	neutral	0,47	1	neutral	0,55	deleterious	0,73	neutral	-6	neutral	0,19	high_impact	2,07	medium_impact	0,14	medium_impact	-0,13	0,66	0,9	13,45	14,46	N	0,32	N	0,62	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7368	7368	T	G	MI.5014	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1465	489	S	A	Tcc/Gcc	-8,47	0	0	benign	0	neutral	0,29	neutral	3,03	neutral	-2,51	neutral	-0,58	low_impact	1,36	neutral	0,77	neutral	0,98	deleterious	0,54	7,72	0,36	0,55	neutral	0,17	neutral	0,24	neutral	0,4	neutral	0,43	1	neutral	0,71	deleterious	0,65	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	-0,02	medium_impact	0,16	0,69	0,9	13,45	14,46	N	0,44	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7368	7368	T	A	MI.5015	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1465	489	S	T	Tcc/Acc	-8,47	0	0	benign	0	neutral	0,39	neutral	2,91	neutral	-2,87	neutral	-0,26	low_impact	1,01	neutral	0,81	neutral	1	deleterious	0,28	5,48	0,32	0,55	neutral	0,27	neutral	0,24	neutral	0,25	neutral	0,44	1	neutral	0,61	deleterious	0,7	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,09	medium_impact	-0,17	0,75	0,9	13,45	14,46	N	0,48	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7369	7369	C	T	MI.5016	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1466	489	S	F	tCc/tTc	-2,48	0	0	benign	0	neutral	0,07	neutral	2,87	deleterious	-4,15	neutral	-1,13	medium_impact	2,8	neutral	0,7	neutral	0,44	neutral	1,22	11,87	0,27	0,55	neutral	0,41	disease	0,54	disease	0,56	disease	0,62	2	neutral	0,93	deleterious	0,54	neutral	-3	neutral	0,16	high_impact	2,07	medium_impact	-0,43	medium_impact	1,49	0,39	0,9	13,45	14,46	N	0,43	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7369	7369	C	G	MI.5017	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1466	489	S	C	tCc/tGc	-2,48	0	0	benign	0,2	deleterious	0,02	neutral	2,84	deleterious	-5,32	neutral	-1,04	medium_impact	3,35	neutral	0,68	neutral	0,64	neutral	0,97	10,49	0,34	0,55	disease	0,6	disease	0,57	neutral	0,5	neutral	0,48	0	neutral	0,98	neutral	0,41	deleterious	1	neutral	0,25	medium_impact	-0,19	medium_impact	-0,75	medium_impact	1,99	0,7	0,9	13,45	14,46	N	0,39	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7369	7369	C	A	MI.5018	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1466	489	S	Y	tCc/tAc	-2,48	0	0	benign	0,02	neutral	0,11	neutral	2,87	deleterious	-4,3	neutral	-0,92	medium_impact	2,38	neutral	0,8	neutral	0,71	neutral	0,94	10,34	0,27	0,55	neutral	0,46	disease	0,6	disease	0,55	disease	0,62	2	neutral	0,89	deleterious	0,55	neutral	-3	neutral	0,16	medium_impact	0,83	medium_impact	-0,31	medium_impact	1,1	0,69	0,9	13,45	14,46	N	0,37	N	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7371	7371	A	G	MI.5019	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1468	490	M	V	Ata/Gta	-8,93	0	0	benign	0	neutral	0,17	neutral	3,05	neutral	1,69	neutral	-0,14	neutral_impact	0,4	neutral	0,73	neutral	0,88	neutral	1,09	11,15	0,58	0,65	neutral	0,15	neutral	0,35	neutral	0,46	neutral	0,44	1	neutral	0,83	deleterious	0,59	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	-0,19	medium_impact	-0,73	0,55	0,9	9,55	41,4	N	0,4	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8761	8761	A	C	MI.502	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	235	79	I	L	Att/Ctt	-2,88	0	0	probably_damaging	0,93	neutral	0,91	neutral	3,64	deleterious	-3,03	neutral	-0,51	neutral_impact	-0,12	neutral	0,73	neutral	0,68	neutral	0,96	10,44	0,31	0,65	neutral	0,44	neutral	0,21	neutral	0,28	neutral	0,37	3	neutral	0,92	deleterious	0,49	neutral	-2	deleterious	0,63	low_impact	-1,82	medium_impact	0,86	low_impact	-1,2	0,59	0,9	49,56	8,5	N	0,25	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7371	7371	A	C	MI.5020	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1468	490	M	L	Ata/Cta	-8,93	0	0	benign	0	neutral	0,06	neutral	3,09	neutral	1,14	neutral	-0,2	neutral_impact	0,4	neutral	0,7	neutral	0,66	neutral	1,63	14,01	0,52	0,6	neutral	0,19	neutral	0,34	neutral	0,4	neutral	0,44	1	neutral	0,94	deleterious	0,53	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	-0,47	medium_impact	-0,73	0,55	0,9	9,55	41,4	N	0,5	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7371	7371	A	T	MI.5021	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1468	490	M	L	Ata/Tta	-8,93	0	0	benign	0	neutral	0,06	neutral	3,09	neutral	1,14	neutral	-0,2	neutral_impact	0,4	neutral	0,7	neutral	0,66	neutral	1,77	14,79	0,52	0,6	neutral	0,19	neutral	0,34	neutral	0,4	neutral	0,44	1	neutral	0,94	deleterious	0,53	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	-0,47	medium_impact	-0,73	0,55	0,9	9,55	41,4	N	0,5	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7372	7372	T	A	MI.5022	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1469	490	M	K	aTa/aAa	4,67	0,98	0	benign	0	deleterious	0,04	neutral	3,01	neutral	1,11	neutral	0,16	neutral_impact	0,55	damaging	0,57	neutral	0,49	deleterious	2,18	17,4	0,32	0,55	neutral	0,22	disease	0,57	disease	0,51	disease	0,53	1	neutral	0,96	deleterious	0,52	neutral	-2	neutral	0,13	high_impact	2,07	medium_impact	-0,58	medium_impact	-0,59	0,62	0,9	9,55	41,4	P	0,53	P	0,16	polymorphism	0,99	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7372	7372	T	C	MI.5023	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1469	490	M	T	aTa/aCa	4,67	0,98	0	benign	0	neutral	0,95	neutral	3,1	neutral	4,65	neutral	0,73	neutral_impact	-2,98	neutral	0,79	neutral	0,97	neutral	-1,21	0,01	0,53	0,6	neutral	0,22	neutral	0,14	neutral	0,27	neutral	0,24	5	neutral	0,05	deleterious	0,98	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,9	low_impact	-3,85	0,24	0,9	9,55	41,4	N	0,49	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7373	7373	A	C	MI.5024	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1470	490	M	I	atA/atC	2,83	0,97	0	benign	0	deleterious	0,02	neutral	3,05	neutral	0,67	neutral	-0,22	neutral_impact	-0,38	neutral	0,75	neutral	0,8	neutral	1,58	13,74	0,55	0,6	neutral	0,26	neutral	0,35	neutral	0,46	neutral	0,44	1	neutral	0,98	deleterious	0,51	neutral	-2	neutral	0,13	high_impact	2,07	medium_impact	-0,75	low_impact	-1,45	0,59	0,9	9,55	41,4	N	0,49	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7373	7373	A	T	MI.5025	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1470	490	M	I	atA/atT	2,83	0,97	0	benign	0	deleterious	0,02	neutral	3,05	neutral	0,67	neutral	-0,22	neutral_impact	-0,38	neutral	0,75	neutral	0,8	neutral	1,66	14,16	0,55	0,6	neutral	0,26	neutral	0,35	neutral	0,46	neutral	0,44	1	neutral	0,98	deleterious	0,51	neutral	-2	neutral	0,13	high_impact	2,07	medium_impact	-0,75	low_impact	-1,45	0,59	0,9	9,55	41,4	N	0,49	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7374	7374	A	G	MI.5026	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1471	491	N	D	Aac/Gac	-8,7	0	0	benign	0,14	deleterious	0,01	neutral	3	neutral	-0,25	neutral	-0,38	medium_impact	3,06	damaging	0,59	neutral	0,48	deleterious	2,2	17,52	0,57	0,6	neutral	0,38	neutral	0,38	neutral	0,46	neutral	0,47	1	deleterious	0,99	neutral	0,44	deleterious	1	neutral	0,25	medium_impact	-0,01	medium_impact	-0,92	medium_impact	1,73	0,47	0,9	10,92	16,37	N	0,46	N	0,76	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7374	7374	A	C	MI.5027	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1471	491	N	H	Aac/Cac	-8,7	0	0	possibly_damaging	0,8	neutral	0,14	neutral	2,93	neutral	-1,52	neutral	-0,57	medium_impact	2,8	damaging	0,56	neutral	0,57	deleterious	3,11	22,5	0,48	0,55	disease	0,54	neutral	0,32	neutral	0,33	disease	0,51	0	neutral	0,92	neutral	0,17	NA	0	deleterious	0,61	low_impact	-1,32	medium_impact	-0,25	medium_impact	1,49	0,52	0,9	10,92	16,37	P	0,5	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7374	7374	A	T	MI.5028	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1471	491	N	Y	Aac/Tac	-8,7	0	0	possibly_damaging	0,87	neutral	0,06	neutral	2,93	neutral	-2,38	neutral	-0,81	medium_impact	2,91	damaging	0,59	neutral	0,33	deleterious	3,78	23,4	0,32	0,55	disease	0,63	neutral	0,45	neutral	0,33	disease	0,62	2	neutral	0,97	neutral	0,1	NA	0	deleterious	0,69	low_impact	-1,53	medium_impact	-0,47	medium_impact	1,59	0,44	0,9	10,92	16,37	N	0,45	N	0,83	polymorphism	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7375	7375	A	G	MI.5029	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1472	491	N	S	aAc/aGc	6,75	1	0	benign	0	neutral	1	neutral	3,26	neutral	4,38	neutral	0,64	neutral_impact	0,25	neutral	0,65	neutral	0,69	neutral	-1,49	0	0,7	0,75	neutral	0,2	neutral	0,04	neutral	0,24	neutral	0,21	6	neutral	0	deleterious	1	neutral	-6	neutral	0,07	high_impact	2,07	high_impact	1,86	medium_impact	-0,87	0,17	0,9	10,92	16,37	P	0,56	P	0,09	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8761	8761	A	G	MI.503	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	235	79	I	V	Att/Gtt	-2,88	0	0	probably_damaging	0,93	neutral	0,2	neutral	3,64	neutral	-1,71	neutral	-0,92	low_impact	1,86	neutral	0,92	neutral	0,47	deleterious	2,95	22,1	0,44	0,65	neutral	0,49	neutral	0,44	disease	0,61	neutral	0,5	0	neutral	0,95	neutral	0,14	neutral	-2	deleterious	0,64	low_impact	-1,82	medium_impact	-0,05	medium_impact	0,5	0,62	0,9	49,56	8,5	N	0,42	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7375	7375	A	C	MI.5030	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1472	491	N	T	aAc/aCc	6,75	1	0	benign	0,14	deleterious	0,04	neutral	3,09	neutral	-0,42	neutral	-0,1	medium_impact	2,19	damaging	0,58	neutral	0,39	neutral	1,63	14,02	0,45	0,55	neutral	0,2	neutral	0,21	neutral	0,45	neutral	0,37	3	neutral	0,96	neutral	0,45	deleterious	1	neutral	0,2	medium_impact	-0,01	medium_impact	-0,58	medium_impact	0,92	0,5	0,9	10,92	16,37	P	0,66	P	0,48	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7375	7375	A	T	MI.5031	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1472	491	N	I	aAc/aTc	6,75	1	0	possibly_damaging	0,83	deleterious	0,02	neutral	2,92	neutral	-1,94	neutral	-0,8	medium_impact	3,26	neutral	0,61	neutral	0,51	deleterious	3,85	23,4	0,29	0,55	disease	0,52	disease	0,54	neutral	0,44	neutral	0,49	0	deleterious	0,99	neutral	0,1	deleterious	4	deleterious	0,64	low_impact	-1,4	medium_impact	-0,75	medium_impact	1,91	0,28	0,9	10,92	16,37	P	0,59	P	0,84	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7376	7376	C	G	MI.5032	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1473	491	N	K	aaC/aaG	3,98	0,99	0	benign	0,39	deleterious	0,01	neutral	2,98	neutral	2,62	neutral	-0,36	high_impact	3,6	damaging	0,59	neutral	0,34	deleterious	2,55	19,81	0,64	0,65	neutral	0,29	neutral	0,44	neutral	0,48	neutral	0,48	0	deleterious	0,99	neutral	0,31	deleterious	2	deleterious	0,46	medium_impact	-0,57	medium_impact	-0,92	high_impact	2,23	0,62	0,9	10,92	16,37	P	0,49	N	0,76	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7376	7376	C	A	MI.5033	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1473	491	N	K	aaC/aaA	3,98	0,99	0	benign	0,39	deleterious	0,01	neutral	2,98	neutral	2,62	neutral	-0,36	high_impact	3,6	damaging	0,59	neutral	0,34	deleterious	3,02	22,3	0,64	0,65	neutral	0,29	neutral	0,44	neutral	0,48	neutral	0,48	0	deleterious	0,99	neutral	0,31	deleterious	2	deleterious	0,46	medium_impact	-0,57	medium_impact	-0,92	high_impact	2,23	0,62	0,9	10,92	16,37	P	0,48	N	0,76	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7377	7377	C	G	MI.5034	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1474	492	L	V	Ctg/Gtg	-3,4	0	0	benign	0	neutral	0,84	neutral	2,74	neutral	0,69	neutral	0,05	neutral_impact	0,8	neutral	0,73	neutral	0,86	deleterious	1,97	16,04	0,46	0,55	neutral	0,43	neutral	0,3	neutral	0,43	neutral	0,46	1	neutral	0,15	deleterious	0,92	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,59	medium_impact	-0,36	0,77	0,9	9,36	29,6	N	0,31	N	0,21	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7377	7377	C	A	MI.5035	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1474	492	L	M	Ctg/Atg	-3,4	0	0	benign	0,06	neutral	0,13	neutral	2,67	neutral	-2,11	neutral	-0,19	low_impact	1,51	neutral	0,74	neutral	0,73	deleterious	2,74	21	0,31	0,55	disease	0,64	neutral	0,22	neutral	0,24	disease	0,52	0	neutral	0,86	deleterious	0,54	neutral	-6	neutral	0,17	medium_impact	0,37	medium_impact	-0,27	medium_impact	0,3	0,68	0,9	9,36	29,6	N	0,51	P	0,25	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7378	7378	T	C	MI.5036	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1475	492	L	P	cTg/cCg	-1,09	0	0	probably_damaging	0,99	neutral	0,42	neutral	2,67	deleterious	-4,57	neutral	-1,34	medium_impact	2,77	damaging	0,59	damaging	0,21	deleterious	4,06	23,7	0,16	0,55	disease	0,88	disease	0,72	neutral	0,34	disease	0,67	3	deleterious	0,99	neutral	0,22	deleterious	1	deleterious	0,85	low_impact	-2,64	medium_impact	0,12	medium_impact	1,46	0,56	0,9	9,36	29,6	N	0,3	N	0,81	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7378	7378	T	G	MI.5037	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1475	492	L	R	cTg/cGg	-1,09	0	0	probably_damaging	0,95	neutral	0,12	neutral	2,67	deleterious	-4,23	neutral	-1,21	medium_impact	2,48	neutral	0,6	damaging	0,11	deleterious	4,31	24	0,18	0,55	disease	0,85	disease	0,73	disease	0,61	disease	0,74	5	neutral	0,98	neutral	0,09	deleterious	1	deleterious	0,83	low_impact	-1,96	medium_impact	-0,29	medium_impact	1,19	0,68	0,9	9,36	29,6	N	0,26	N	0,89	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7378	7378	T	A	MI.5038	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1475	492	L	Q	cTg/cAg	-1,09	0	0	probably_damaging	0,95	neutral	0,09	neutral	2,65	deleterious	-4,35	neutral	-1,19	medium_impact	3,12	neutral	0,68	damaging	0,15	deleterious	3,31	22,9	0,2	0,55	disease	0,85	disease	0,57	neutral	0,32	disease	0,6	2	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,78	low_impact	-1,96	medium_impact	-0,37	medium_impact	1,78	0,7	0,9	9,36	29,6	N	0,35	N	0,69	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7380	7380	G	A	MI.5039	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1477	493	E	K	Gag/Aag	-5,7	0	0	probably_damaging	1	deleterious	0	neutral	2,41	deleterious	-7,87	neutral	-1,19	high_impact	4,45	damaging	0,5	damaging	0,11	deleterious	4,63	24,5	0,42	0,55	disease	0,77	disease	0,77	disease	0,62	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	3,01	0,67	0,9	2,34	8,25	N	0,4	N	0,72	polymorphism	0,91	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8762	8762	T	A	MI.504	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	236	79	I	N	aTt/aAt	1,29	0,65	0	probably_damaging	1	deleterious	0	neutral	3,3	deleterious	-7,66	deleterious	-5,76	high_impact	3,77	neutral	0,84	neutral	0,39	deleterious	4,15	23,8	0,22	0,65	disease	0,93	disease	0,82	disease	0,65	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,6	low_impact	-1,4	high_impact	2,13	0,4	0,9	49,56	8,5	N	0,38	N	0,99	polymorphism	0,99	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7380	7380	G	C	MI.5040	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1477	493	E	Q	Gag/Cag	-5,7	0	0	probably_damaging	0,99	deleterious	0	neutral	2,38	deleterious	-8,18	neutral	-0,89	high_impact	4,79	damaging	0,57	damaging	0,16	deleterious	3,54	23,1	0,43	0,55	disease	0,77	disease	0,63	disease	0,59	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,64	low_impact	-1,48	high_impact	3,32	0,79	0,9	2,34	8,25	P	0,62	P	0,66	polymorphism	0,98	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7381	7381	A	G	MI.5041	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1478	493	E	G	gAg/gGg	6,06	1	0	probably_damaging	1	deleterious	0	neutral	2,4	deleterious	-8,1	neutral	-2,09	high_impact	4,79	damaging	0,45	damaging	0,19	deleterious	4,58	24,4	0,3	0,55	disease	0,78	disease	0,61	disease	0,56	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,32	0,5	0,9	2,34	8,25	P	0,69	P	0,67	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7381	7381	A	C	MI.5042	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1478	493	E	A	gAg/gCg	6,06	1	0	probably_damaging	1	deleterious	0,04	neutral	2,39	deleterious	-8,07	neutral	-1,79	high_impact	4,79	neutral	0,65	damaging	0,16	deleterious	4,05	23,7	0,23	0,55	disease	0,78	disease	0,69	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,85	low_impact	-3,58	medium_impact	-0,58	high_impact	3,32	0,63	0,9	2,34	8,25	P	0,69	P	0,7	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7381	7381	A	T	MI.5043	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1478	493	E	V	gAg/gTg	6,06	1	0	probably_damaging	1	deleterious	0	neutral	2,34	deleterious	-9,33	neutral	-2,09	high_impact	4,79	damaging	0,51	damaging	0,14	deleterious	4,61	24,4	0,21	0,55	disease	0,91	disease	0,81	disease	0,69	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,58	low_impact	-1,48	high_impact	3,32	0,68	0,9	2,34	8,25	P	0,68	P	0,68	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7382	7382	G	C	MI.5044	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1479	493	E	D	gaG/gaC	8,59	1	0	probably_damaging	0,97	deleterious	0	neutral	2,44	deleterious	-6,85	neutral	-0,89	high_impact	3,64	damaging	0,55	damaging	0,15	deleterious	3,86	23,5	0,47	0,55	neutral	0,39	disease	0,58	neutral	0,42	neutral	0,46	1	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-2,18	low_impact	-1,48	high_impact	2,26	0,84	0,9	2,34	8,25	P	0,51	P	0,7	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7382	7382	G	T	MI.5045	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1479	493	E	D	gaG/gaT	8,59	1	0	probably_damaging	0,97	deleterious	0	neutral	2,44	deleterious	-6,85	neutral	-0,89	high_impact	3,64	damaging	0,55	damaging	0,15	deleterious	4,01	23,6	0,47	0,55	neutral	0,39	disease	0,58	neutral	0,42	neutral	0,46	1	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-2,18	low_impact	-1,48	high_impact	2,26	0,84	0,9	2,34	8,25	P	0,52	P	0,7	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7383	7383	T	C	MI.5046	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1480	494	W	R	Tga/Cga	-2,48	0	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-8,09	deleterious	-4,13	high_impact	4,42	neutral	0,65	damaging	0,05	deleterious	3,8	23,4	0,31	0,55	disease	0,73	disease	0,84	disease	0,75	disease	0,78	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,98	0,25	0,9	2,14	6,66	N	0,43	N	0,94	disease_causing	0,93	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7383	7383	T	G	MI.5047	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1480	494	W	G	Tga/Gga	-2,48	0	0	probably_damaging	1	deleterious	0	neutral	2,62	deleterious	-7,99	deleterious	-3,84	high_impact	4,42	neutral	0,67	damaging	0,06	deleterious	4,1	23,7	0,27	0,55	disease	0,72	disease	0,75	disease	0,72	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,58	low_impact	-1,48	high_impact	2,98	0,27	0,9	2,14	6,66	N	0,4	N	0,9	disease_causing	0,98	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7384	7384	G	C	MI.5048	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1481	494	W	S	tGa/tCa	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-7,83	deleterious	-4,12	high_impact	3,96	neutral	0,68	damaging	0,05	deleterious	4,21	23,9	0,23	0,55	disease	0,6	disease	0,87	disease	0,7	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	2,56	0,2	0,9	2,14	6,66	N	0,41	N	0,88	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7384	7384	G	T	MI.5049	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1481	494	W	L	tGa/tTa	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,7	deleterious	-6,41	deleterious	-3,83	high_impact	4,07	neutral	0,71	damaging	0,04	deleterious	4,48	24,2	0,23	0,55	disease	0,54	disease	0,77	disease	0,67	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,66	0,22	0,9	2,14	6,66	N	0,47	N	0,95	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8762	8762	T	C	MI.505	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	236	79	I	T	aTt/aCt	1,29	0,65	0	probably_damaging	0,99	deleterious	0	neutral	3,34	deleterious	-5,51	deleterious	-3,88	medium_impact	3,42	neutral	0,89	neutral	0,43	deleterious	3,18	22,7	0,4	0,65	disease	0,78	disease	0,6	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,77	low_impact	-2,65	low_impact	-1,4	medium_impact	1,83	0,53	0,9	49,56	8,5	N	0,44	N	0,7	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7385	7385	A	C	MI.5050	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1482	494	W	C	tgA/tgC	7,21	1	0,01	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-9,38	deleterious	-3,84	high_impact	4,76	neutral	0,63	damaging	0,04	deleterious	4,2	23,9	0,26	0,55	disease	0,84	disease	0,83	disease	0,78	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,17	0,9	2,14	6,66	P	0,66	P	0,88	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7385	7385	A	T	MI.5051	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1482	494	W	C	tgA/tgT	7,21	1	0,01	probably_damaging	1	deleterious	0	neutral	2,58	deleterious	-9,38	deleterious	-3,84	high_impact	4,76	neutral	0,63	damaging	0,04	deleterious	4,32	24	0,26	0,55	disease	0,84	disease	0,83	disease	0,78	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,3	0,17	0,9	2,14	6,66	P	0,66	P	0,88	disease_causing	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7386	7386	C	A	MI.5052	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1483	495	L	M	Cta/Ata	2,6	0,98	0	possibly_damaging	0,79	neutral	0,11	neutral	2,83	neutral	-1,4	neutral	0,06	low_impact	1,9	neutral	0,72	neutral	0,92	deleterious	2,62	20,3	0,29	0,55	neutral	0,42	neutral	0,08	neutral	0,17	neutral	0,32	4	neutral	0,93	neutral	0,16	neutral	-3	deleterious	0,53	low_impact	-1,3	medium_impact	-0,31	medium_impact	0,66	0,73	0,9	8,38	10,14	P	0,64	P	0,55	disease_causing	0,9	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7386	7386	C	G	MI.5053	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1483	495	L	V	Cta/Gta	2,6	0,98	0	benign	0,05	neutral	0,16	neutral	2,87	neutral	-0,26	neutral	-0,16	medium_impact	3,23	neutral	0,71	damaging	0,21	deleterious	2,35	18,51	0,39	0,55	neutral	0,25	neutral	0,2	neutral	0,33	neutral	0,36	3	neutral	0,83	deleterious	0,56	neutral	-3	neutral	0,1	medium_impact	0,45	medium_impact	-0,21	medium_impact	1,88	0,54	0,9	8,38	10,14	P	0,65	P	0,64	disease_causing	0,92	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7387	7387	T	G	MI.5054	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1484	495	L	R	cTa/cGa	-0,86	0,02	0	possibly_damaging	0,88	neutral	0,05	neutral	2,82	neutral	1,58	neutral	-0,44	high_impact	4,26	damaging	0,56	damaging	0,12	deleterious	3,22	22,7	0,24	0,55	neutral	0,43	disease	0,56	neutral	0,46	neutral	0,49	0	neutral	0,98	neutral	0,09	deleterious	1	deleterious	0,7	low_impact	-1,57	medium_impact	-0,52	high_impact	2,83	0,55	0,9	8,38	10,14	N	0,43	N	0,88	polymorphism	0,86	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7387	7387	T	C	MI.5055	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1484	495	L	P	cTa/cCa	-0,86	0,02	0	probably_damaging	0,96	deleterious	0,03	neutral	2,83	neutral	-0,87	neutral	-0,72	high_impact	3,92	damaging	0,55	damaging	0,13	deleterious	4,1	23,7	0,17	0,55	disease	0,58	disease	0,64	neutral	0,29	neutral	0,49	0	deleterious	0,99	neutral	0,04	deleterious	6	deleterious	0,76	low_impact	-2,06	medium_impact	-0,65	high_impact	2,52	0,36	0,9	8,38	10,14	N	0,39	N	0,86	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7387	7387	T	A	MI.5056	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1484	495	L	Q	cTa/cAa	-0,86	0,02	0	probably_damaging	0,91	neutral	0,12	neutral	2,84	neutral	0,69	neutral	-0,27	medium_impact	2,65	neutral	0,68	damaging	0,23	deleterious	3	22,2	0,25	0,55	neutral	0,34	neutral	0,31	neutral	0,24	neutral	0,47	1	neutral	0,96	neutral	0,11	deleterious	1	deleterious	0,64	low_impact	-1,7	medium_impact	-0,29	medium_impact	1,35	0,57	0,9	8,38	10,14	N	0,47	N	0,84	polymorphism	0,88	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7389	7389	T	C	MI.5057	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1486	496	Y	H	Tat/Cat	-11,24	0	0,01	benign	0	neutral	1	neutral	3,02	neutral	2,06	neutral	0,5	neutral_impact	-2,33	neutral	0,76	neutral	0,98	neutral	-0,96	0,02	0,64	0,65	neutral	0,2	neutral	0,13	neutral	0,19	neutral	0,27	5	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,07	high_impact	1,86	low_impact	-3,25	0,27	0,9	11,5	36,42	N	0,37	N	0,03	polymorphism	1	0	rs9783095	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7389	7389	T	G	MI.5058	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1486	496	Y	D	Tat/Gat	-11,24	0	0,01	benign	0,02	neutral	0,1	neutral	2,99	neutral	1,69	neutral	-0,09	neutral_impact	0,31	damaging	0,59	neutral	0,36	neutral	0,94	10,3	0,42	0,55	neutral	0,24	neutral	0,48	neutral	0,45	neutral	0,45	1	neutral	0,9	deleterious	0,54	neutral	-6	neutral	0,12	medium_impact	0,83	medium_impact	-0,34	medium_impact	-0,81	0,32	0,9	11,5	36,42	N	0,46	N	0,55	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7389	7389	T	A	MI.5059	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1486	496	Y	N	Tat/Aat	-11,24	0	0,01	benign	0	neutral	0,34	neutral	3,01	neutral	2,1	neutral	0,14	neutral_impact	-1,66	neutral	0,85	neutral	0,98	deleterious	0,61	8,21	0,42	0,55	neutral	0,19	neutral	0,37	neutral	0,25	neutral	0,45	1	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,03	low_impact	-2,63	0,19	0,9	11,5	36,42	N	0,37	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8762	8762	T	G	MI.506	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	236	79	I	S	aTt/aGt	1,29	0,65	0	probably_damaging	0,99	deleterious	0	neutral	3,3	deleterious	-5,88	deleterious	-4,8	medium_impact	3,21	neutral	0,81	neutral	0,46	deleterious	4,11	23,7	0,21	0,65	disease	0,56	disease	0,81	disease	0,62	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,76	low_impact	-2,65	low_impact	-1,4	medium_impact	1,65	0,37	0,9	49,56	8,5	N	0,33	N	0,89	polymorphism	0,99	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7390	7390	A	C	MI.5060	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1487	496	Y	S	tAt/tCt	0,29	0,02	0	benign	0,02	neutral	0,16	neutral	3	neutral	1,98	neutral	-0,04	neutral_impact	-0,28	neutral	0,61	neutral	0,56	deleterious	0,72	8,99	0,29	0,55	neutral	0,17	neutral	0,33	neutral	0,29	neutral	0,45	1	neutral	0,83	deleterious	0,57	neutral	-6	neutral	0,12	medium_impact	0,83	medium_impact	-0,21	low_impact	-1,36	0,3	0,9	11,5	36,42	N	0,51	P	0,36	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7390	7390	A	T	MI.5061	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1487	496	Y	F	tAt/tTt	0,29	0,02	0	benign	0,05	neutral	0,26	neutral	3	neutral	-0,63	neutral	-0,57	neutral_impact	0,48	neutral	0,65	neutral	0,64	deleterious	0,2	4,66	0,39	0,55	neutral	0,27	neutral	0,27	neutral	0,32	neutral	0,43	1	neutral	0,72	deleterious	0,61	neutral	-6	neutral	0,13	medium_impact	0,45	medium_impact	-0,06	medium_impact	-0,66	0,26	0,9	11,5	36,42	N	0,51	P	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7390	7390	A	G	MI.5062	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1487	496	Y	C	tAt/tGt	0,29	0,02	0	possibly_damaging	0,48	neutral	0,07	neutral	2,96	neutral	-1,41	neutral	-0,78	low_impact	0,94	neutral	0,61	neutral	0,38	deleterious	2,14	17,11	0,37	0,55	neutral	0,25	disease	0,57	neutral	0,29	neutral	0,49	0	neutral	0,92	neutral	0,3	neutral	-3	deleterious	0,44	medium_impact	-0,72	medium_impact	-0,43	medium_impact	-0,23	0,12	0,9	11,5	36,42	N	0,46	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7392	7392	G	C	MI.5063	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1489	497	G	R	Gga/Cga	-1,78	0	0	probably_damaging	1	neutral	0,06	neutral	3	neutral	-0,08	neutral	-0,06	medium_impact	2,29	neutral	0,61	damaging	0,09	deleterious	2,61	20,3	0,37	0,55	neutral	0,25	disease	0,57	neutral	0,35	disease	0,5	0	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,67	low_impact	-3,58	medium_impact	-0,47	medium_impact	1,02	0,72	0,9	2,92	6,67	N	0,37	N	0,9	disease_causing	0,93	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7392	7392	G	T	MI.5064	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1489	497	G	W	Gga/Tga	-1,78	0	0	probably_damaging	1	deleterious	0,01	neutral	2,96	deleterious	-3,29	neutral	-0,93	medium_impact	2,63	neutral	0,63	damaging	0,1	deleterious	3,44	23	0,22	0,55	disease	0,79	disease	0,6	disease	0,52	disease	0,63	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,76	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,33	0,42	0,9	2,92	6,67	N	0,29	N	0,83	disease_causing	0,96	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7393	7393	G	C	MI.5065	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1490	497	G	A	gGa/gCa	6,06	1	0	probably_damaging	1	neutral	0,06	neutral	3,06	neutral	0,64	neutral	-0,36	medium_impact	2,04	neutral	0,68	damaging	0,17	neutral	1,59	13,79	0,41	0,55	neutral	0,17	neutral	0,27	neutral	0,27	neutral	0,43	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,62	low_impact	-3,58	medium_impact	-0,47	medium_impact	0,79	0,61	0,9	2,92	6,67	P	0,58	P	0,66	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7393	7393	G	A	MI.5066	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1490	497	G	E	gGa/gAa	6,06	1	0	probably_damaging	1	neutral	0,09	neutral	3	neutral	0,88	neutral	-0,1	medium_impact	2,17	neutral	0,65	damaging	0,1	deleterious	2,5	19,48	0,4	0,55	neutral	0,15	disease	0,51	neutral	0,44	neutral	0,41	2	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,63	low_impact	-3,58	medium_impact	-0,37	medium_impact	0,91	0,53	0,9	2,92	6,67	P	0,52	P	0,92	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7393	7393	G	T	MI.5067	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1490	497	G	V	gGa/gTa	6,06	1	0	probably_damaging	1	neutral	0,07	neutral	3,04	neutral	-0,49	neutral	-0,7	medium_impact	2,42	neutral	0,6	damaging	0,1	deleterious	2,36	18,58	0,37	0,55	neutral	0,38	neutral	0,43	neutral	0,38	neutral	0,46	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,67	low_impact	-3,58	medium_impact	-0,43	medium_impact	1,14	0,43	0,9	2,92	6,67	P	0,54	P	0,92	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7395	7395	T	A	MI.5068	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1492	498	C	S	Tgc/Agc	-4,55	0	0	benign	0	neutral	0,55	neutral	3,19	neutral	-0,6	neutral	-0,18	low_impact	0,95	neutral	0,67	neutral	0,57	deleterious	0,09	3,54	0,43	0,55	neutral	0,24	neutral	0,12	neutral	0,41	neutral	0,3	4	neutral	0,45	deleterious	0,78	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,24	medium_impact	-0,22	0,44	0,9	7,6	41,15	N	0,39	N	0,81	polymorphism	0,99	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7395	7395	T	C	MI.5069	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1492	498	C	R	Tgc/Cgc	-4,55	0	0	benign	0,31	neutral	0,1	neutral	3,02	neutral	-1,59	neutral	-0,51	medium_impact	2,8	damaging	0,58	neutral	0,34	deleterious	0,87	9,91	0,29	0,55	neutral	0,29	disease	0,57	disease	0,63	disease	0,73	5	neutral	0,88	neutral	0,4	neutral	-3	deleterious	0,5	medium_impact	-0,43	medium_impact	-0,34	medium_impact	1,49	0,2	0,9	7,6	41,15	N	0,39	N	0,8	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8763	8763	T	G	MI.507	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	237	79	I	M	atT/atG	5,68	0,95	0	probably_damaging	1	deleterious	0,04	neutral	3,34	deleterious	-5,44	neutral	-1,76	medium_impact	2,73	neutral	0,84	neutral	0,42	deleterious	3,31	22,9	0,34	0,65	disease	0,85	disease	0,64	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-3,6	medium_impact	-0,49	medium_impact	1,24	0,76	0,9	49,56	8,5	N	0,5	N	0,8	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7395	7395	T	G	MI.5070	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1492	498	C	G	Tgc/Ggc	-4,55	0	0	benign	0,09	neutral	0,26	neutral	3,02	neutral	-1,92	neutral	-0,75	medium_impact	2,8	neutral	0,63	neutral	0,48	deleterious	0,44	6,93	0,29	0,55	neutral	0,36	neutral	0,38	disease	0,57	neutral	0,48	0	neutral	0,71	deleterious	0,59	neutral	-3	neutral	0,2	medium_impact	0,19	medium_impact	-0,06	medium_impact	1,49	0,32	0,9	7,6	41,15	N	0,45	N	0,88	polymorphism	0,98	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7396	7396	G	C	MI.5071	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1493	498	C	S	tGc/tCc	7,44	1	0	benign	0	neutral	0,55	neutral	3,19	neutral	-0,6	neutral	-0,18	low_impact	0,95	neutral	0,67	neutral	0,57	neutral	-0,34	0,54	0,43	0,55	neutral	0,24	neutral	0,12	neutral	0,41	neutral	0,3	4	neutral	0,45	deleterious	0,78	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,24	medium_impact	-0,22	0,44	0,9	7,6	41,15	P	0,59	P	0,81	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7396	7396	G	A	MI.5072	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1493	498	C	Y	tGc/tAc	7,44	1	0	possibly_damaging	0,65	neutral	0,53	neutral	3,08	neutral	2,16	neutral	0,06	neutral_impact	0,7	damaging	0,58	neutral	0,56	neutral	1,35	12,54	0,37	0,55	neutral	0,46	neutral	0,32	neutral	0,35	neutral	0,45	1	neutral	0,62	neutral	0,44	neutral	-3	deleterious	0,56	low_impact	-1,01	medium_impact	0,22	medium_impact	-0,45	0,5	0,9	7,6	41,15	P	0,55	P	0,9	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7396	7396	G	T	MI.5073	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1493	498	C	F	tGc/tTc	7,44	1	0	possibly_damaging	0,57	neutral	0,35	neutral	3,06	neutral	-0,46	neutral	0,21	low_impact	0,96	damaging	0,6	neutral	0,62	neutral	1,65	14,11	0,36	0,55	neutral	0,44	neutral	0,34	neutral	0,32	neutral	0,46	1	neutral	0,66	neutral	0,39	neutral	-3	deleterious	0,53	medium_impact	-0,87	medium_impact	0,04	medium_impact	-0,21	0,42	0,9	7,6	41,15	P	0,62	P	0,97	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7397	7397	C	A	MI.5074	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1494	498	C	W	tgC/tgA	6,06	1	0	possibly_damaging	0,8	neutral	0,05	neutral	2,99	deleterious	-3,46	neutral	-0,3	medium_impact	3,15	neutral	0,61	neutral	0,37	deleterious	3,48	23,1	0,31	0,55	disease	0,67	disease	0,6	neutral	0,47	neutral	0,5	0	neutral	0,97	neutral	0,13	NA	0	deleterious	0,69	low_impact	-1,32	medium_impact	-0,52	medium_impact	1,81	0,26	0,9	7,6	41,15	P	0,6	P	0,93	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7397	7397	C	G	MI.5075	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1494	498	C	W	tgC/tgG	6,06	1	0	possibly_damaging	0,8	neutral	0,05	neutral	2,99	deleterious	-3,46	neutral	-0,3	medium_impact	3,15	neutral	0,61	neutral	0,37	deleterious	3,21	22,7	0,31	0,55	disease	0,67	disease	0,6	neutral	0,47	neutral	0,5	0	neutral	0,97	neutral	0,13	NA	0	deleterious	0,69	low_impact	-1,32	medium_impact	-0,52	medium_impact	1,81	0,26	0,9	7,6	41,15	P	0,59	P	0,93	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7398	7398	C	T	MI.5076	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1495	499	P	S	Ccc/Tcc	-2,48	0	0	probably_damaging	1	deleterious	0,01	neutral	2,27	deleterious	-5,61	neutral	-2,16	medium_impact	3,4	neutral	0,72	damaging	0,05	deleterious	4,12	23,8	0,35	0,55	neutral	0,3	disease	0,72	disease	0,67	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,76	low_impact	-3,58	medium_impact	-0,92	high_impact	2,04	0,21	0,9	NA	NA	N	0,28	N	0,84	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7398	7398	C	G	MI.5077	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1495	499	P	A	Ccc/Gcc	-2,48	0	0	probably_damaging	0,99	deleterious	0,01	neutral	2,28	deleterious	-5,67	neutral	-2,17	high_impact	4,38	neutral	0,71	damaging	0,06	deleterious	3,23	22,8	0,31	0,55	neutral	0,48	disease	0,64	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,76	low_impact	-2,64	medium_impact	-0,92	high_impact	2,95	0,56	0,9	NA	NA	N	0,4	N	0,76	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7398	7398	C	A	MI.5078	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1495	499	P	T	Ccc/Acc	-2,48	0	0	probably_damaging	1	deleterious	0	neutral	2,28	deleterious	-6,2	neutral	-2,15	high_impact	4,04	neutral	0,71	damaging	0,05	deleterious	3,86	23,5	0,33	0,55	disease	0,59	disease	0,8	disease	0,74	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,58	low_impact	-1,48	high_impact	2,63	0,47	0,9	NA	NA	N	0,33	N	0,82	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7399	7399	C	G	MI.5079	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1496	499	P	R	cCc/cGc	4,44	0,99	0	probably_damaging	1	deleterious	0	neutral	2,26	deleterious	-6,32	neutral	-2,44	high_impact	4,38	neutral	0,71	damaging	0,04	deleterious	3,84	23,4	0,28	0,55	disease	0,86	disease	0,82	disease	0,8	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,58	low_impact	-1,48	high_impact	2,95	0,49	0,9	NA	NA	P	0,5	N	0,87	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8763	8763	T	A	MI.508	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	237	79	I	M	atT/atA	5,68	0,95	0	probably_damaging	1	deleterious	0,04	neutral	3,34	deleterious	-5,44	neutral	-1,76	medium_impact	2,73	neutral	0,84	neutral	0,42	deleterious	3,6	23,2	0,34	0,65	disease	0,85	disease	0,64	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-3,6	medium_impact	-0,49	medium_impact	1,24	0,76	0,9	49,56	8,5	N	0,52	P	0,8	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7399	7399	C	A	MI.5080	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1496	499	P	H	cCc/cAc	4,44	0,99	0	probably_damaging	1	deleterious	0,03	neutral	2,24	deleterious	-7,11	neutral	-2,41	high_impact	4,73	neutral	0,72	damaging	0,04	deleterious	4,22	23,9	0,3	0,55	disease	0,92	disease	0,79	disease	0,78	disease	0,87	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,85	low_impact	-3,58	medium_impact	-0,65	high_impact	3,27	0,45	0,9	NA	NA	P	0,67	P	0,82	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7399	7399	C	T	MI.5081	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1496	499	P	L	cCc/cTc	4,44	0,99	0	probably_damaging	1	deleterious	0	neutral	2,31	deleterious	-7,04	deleterious	-2,62	high_impact	4,73	neutral	0,71	damaging	0,04	deleterious	4,62	24,5	0,3	0,55	disease	0,85	disease	0,8	disease	0,73	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,58	low_impact	-1,48	high_impact	3,27	0,65	0,9	NA	NA	P	0,68	P	0,89	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7401	7401	C	G	MI.5082	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1498	500	P	A	Cca/Gca	-5,47	0	0	probably_damaging	0,99	deleterious	0,02	neutral	2,68	deleterious	-5,86	neutral	-1,94	high_impact	3,8	neutral	0,7	damaging	0,17	deleterious	3,21	22,7	0,29	0,55	neutral	0,27	disease	0,6	disease	0,55	neutral	0,45	1	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,71	low_impact	-2,64	medium_impact	-0,75	high_impact	2,41	0,68	0,9	NA	NA	N	0,38	N	0,76	polymorphism	0,94	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7401	7401	C	A	MI.5083	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1498	500	P	T	Cca/Aca	-5,47	0	0	probably_damaging	1	deleterious	0,01	neutral	2,64	deleterious	-6,39	neutral	-1,97	high_impact	4,14	neutral	0,69	damaging	0,12	deleterious	3,9	23,5	0,3	0,55	neutral	0,39	disease	0,79	neutral	0,35	disease	0,6	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,75	low_impact	-3,58	medium_impact	-0,92	high_impact	2,72	0,58	0,9	NA	NA	N	0,35	N	0,82	polymorphism	0,91	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7401	7401	C	T	MI.5084	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1498	500	P	S	Cca/Tca	-5,47	0	0	probably_damaging	1	deleterious	0,02	neutral	2,65	deleterious	-5,8	neutral	-1,98	medium_impact	3,19	neutral	0,63	damaging	0,14	deleterious	4,1	23,7	0,33	0,55	neutral	0,38	disease	0,69	neutral	0,37	disease	0,51	0	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,75	low_impact	-3,58	medium_impact	-0,75	medium_impact	1,85	0,28	0,9	NA	NA	N	0,35	N	0,84	polymorphism	0,9	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7402	7402	C	G	MI.5085	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1499	500	P	R	cCa/cGa	5,6	1	0	probably_damaging	1	deleterious	0	neutral	2,63	deleterious	-6,52	neutral	-2,26	high_impact	4,69	neutral	0,7	damaging	0,08	deleterious	3,76	23,4	0,26	0,55	neutral	0,44	disease	0,8	disease	0,71	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	high_impact	3,23	0,51	0,9	NA	NA	P	0,55	P	0,87	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7402	7402	C	A	MI.5086	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1499	500	P	Q	cCa/cAa	5,6	1	0	probably_damaging	1	deleterious	0	neutral	2,61	deleterious	-6,14	neutral	-2,01	high_impact	4,34	neutral	0,71	damaging	0,09	deleterious	4,22	23,9	0,22	0,55	neutral	0,41	disease	0,78	disease	0,66	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,75	low_impact	-3,58	low_impact	-1,48	high_impact	2,91	0,41	0,9	NA	NA	N	0,44	N	0,83	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7402	7402	C	T	MI.5087	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1499	500	P	L	cCa/cTa	5,6	1	0	probably_damaging	1	neutral	0,1	neutral	2,7	deleterious	-7,23	neutral	-2,44	medium_impact	3,27	damaging	0,55	damaging	0,11	deleterious	3,48	23,1	0,35	0,55	disease	0,54	disease	0,76	disease	0,55	disease	0,54	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,77	low_impact	-3,58	medium_impact	-0,34	medium_impact	1,92	0,7	0,9	NA	NA	N	0,47	N	0,89	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7404	7404	C	G	MI.5088	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1501	501	P	A	Ccc/Gcc	-10,55	0	0	benign	0	neutral	0,62	neutral	2,98	neutral	2,25	neutral	0,47	neutral_impact	0,5	neutral	0,67	neutral	0,3	neutral	-1,34	0	0,25	0,55	neutral	0,23	neutral	0,07	neutral	0,16	neutral	0,24	5	neutral	0,37	deleterious	0,81	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,31	medium_impact	-0,64	0,53	0,9	4,48	8	N	0,47	N	0,76	polymorphism	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7404	7404	C	T	MI.5089	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1501	501	P	S	Ccc/Tcc	-10,55	0	0	benign	0,28	neutral	0,36	neutral	2,89	neutral	3,23	neutral	0,32	neutral_impact	0,66	neutral	0,65	neutral	0,32	deleterious	0,01	2,73	0,32	0,55	neutral	0,19	neutral	0,14	neutral	0,16	neutral	0,26	5	neutral	0,56	deleterious	0,54	neutral	-6	neutral	0,33	medium_impact	-0,37	medium_impact	0,05	medium_impact	-0,49	0,31	0,9	4,48	8	N	0,51	P	0,84	polymorphism	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8764	8764	G	C	MI.509	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	238	80	A	P	Gcc/Ccc	-7,51	0	0,02	possibly_damaging	0,55	deleterious	0,01	neutral	4,35	neutral	-2,79	deleterious	-2,62	low_impact	1,5	neutral	0,79	neutral	0,4	deleterious	3,28	22,8	0,17	0,65	disease	0,77	disease	0,77	disease	0,59	disease	0,75	5	deleterious	0,99	neutral	0,23	deleterious	1	deleterious	0,67	medium_impact	-0,84	medium_impact	-0,84	medium_impact	0,19	0,75	0,9	25,66	23,52	N	0,27	N	0,88	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7404	7404	C	A	MI.5090	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1501	501	P	T	Ccc/Acc	-10,55	0	0	benign	0,28	neutral	0,15	neutral	2,87	neutral	2,11	neutral	0,07	low_impact	1,1	neutral	0,67	damaging	0,18	deleterious	0,64	8,41	0,23	0,55	neutral	0,33	neutral	0,25	neutral	0,34	neutral	0,45	1	neutral	0,82	neutral	0,44	neutral	-6	neutral	0,28	medium_impact	-0,37	medium_impact	-0,23	medium_impact	-0,08	0,5	0,9	4,48	8	N	0,43	N	0,82	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7405	7405	C	A	MI.5091	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1502	501	P	H	cCc/cAc	3,52	0,98	0	probably_damaging	0,93	neutral	0,06	neutral	2,83	neutral	0,05	neutral	-0,39	medium_impact	2,46	neutral	0,67	damaging	0,12	deleterious	3,1	22,5	0,25	0,55	neutral	0,45	neutral	0,3	neutral	0,28	neutral	0,47	1	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,65	low_impact	-1,81	medium_impact	-0,47	medium_impact	1,17	0,46	0,9	4,48	8	P	0,52	P	0,82	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7405	7405	C	T	MI.5092	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1502	501	P	L	cCc/cTc	3,52	0,98	0	possibly_damaging	0,5	neutral	0,29	neutral	2,96	neutral	5,07	neutral	-0,22	low_impact	0,98	neutral	0,64	damaging	0,1	neutral	1,7	14,43	0,28	0,55	neutral	0,35	neutral	0,34	neutral	0,36	neutral	0,45	1	neutral	0,68	neutral	0,4	neutral	-3	deleterious	0,48	medium_impact	-0,76	medium_impact	-0,02	medium_impact	-0,19	0,74	0,9	4,48	8	N	0,49	N	0,89	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7405	7405	C	G	MI.5093	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1502	501	P	R	cCc/cGc	3,52	0,98	0	possibly_damaging	0,88	neutral	0,12	neutral	2,85	neutral	0,61	neutral	-0,25	medium_impact	3,36	neutral	0,64	damaging	0,09	deleterious	2,23	17,69	0,25	0,55	neutral	0,32	neutral	0,43	neutral	0,46	neutral	0,49	0	neutral	0,95	neutral	0,12	NA	0	deleterious	0,61	low_impact	-1,57	medium_impact	-0,29	high_impact	2	0,54	0,9	4,48	8	N	0,5	N	0,87	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7407	7407	T	C	MI.5094	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1504	502	Y	H	Tac/Cac	-5,01	0	0	benign	0,01	neutral	0,55	neutral	2,98	neutral	1,1	neutral	0,29	low_impact	1,16	neutral	0,72	neutral	0,77	deleterious	0,04	2,96	0,64	0,65	neutral	0,19	neutral	0,29	neutral	0,26	neutral	0,43	1	neutral	0,44	deleterious	0,77	neutral	-6	neutral	0,11	medium_impact	1,12	medium_impact	0,24	medium_impact	-0,03	0,27	0,9	11,89	12,5	N	0,35	N	0,64	polymorphism	1	0	rs201121626	.	.	.	.	.	COSM1138404	.	.	.	.	.	.	.	.
chrM	7407	7407	T	A	MI.5095	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1504	502	Y	N	Tac/Aac	-5,01	0	0	benign	0,25	neutral	0,27	neutral	3	neutral	2,71	neutral	0,2	low_impact	0,98	neutral	0,64	neutral	0,48	neutral	1,06	10,98	0,43	0,55	neutral	0,3	disease	0,5	neutral	0,37	neutral	0,46	1	neutral	0,67	deleterious	0,51	neutral	-6	neutral	0,29	medium_impact	-0,31	medium_impact	-0,05	medium_impact	-0,19	0,31	0,9	11,89	12,5	N	0,41	N	0,95	polymorphism	0,95	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7407	7407	T	G	MI.5096	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1504	502	Y	D	Tac/Gac	-5,01	0	0	benign	0,32	neutral	0,2	neutral	2,98	neutral	3,6	neutral	0,63	low_impact	1,22	neutral	0,69	neutral	0,64	deleterious	2,18	17,38	0,44	0,55	neutral	0,31	neutral	0,43	neutral	0,45	neutral	0,46	1	neutral	0,76	neutral	0,44	neutral	-6	deleterious	0,44	medium_impact	-0,45	medium_impact	-0,14	medium_impact	0,03	0,39	0,9	11,89	12,5	N	0,41	N	0,98	polymorphism	0,96	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7408	7408	A	C	MI.5097	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1505	502	Y	S	tAc/tCc	1,91	0,95	0	benign	0,16	neutral	0,33	neutral	3,02	neutral	2,36	neutral	0,14	low_impact	1,06	neutral	0,64	neutral	0,52	neutral	1,2	11,73	0,32	0,55	neutral	0,16	neutral	0,41	neutral	0,37	neutral	0,44	1	neutral	0,61	deleterious	0,59	neutral	-6	neutral	0,32	medium_impact	-0,08	medium_impact	0,02	medium_impact	-0,12	0,27	0,9	11,89	12,5	N	0,44	N	0,9	polymorphism	0,57	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7408	7408	A	T	MI.5098	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1505	502	Y	F	tAc/tTc	1,91	0,95	0	benign	0	neutral	0,61	neutral	3,03	neutral	-0,51	neutral	-0,19	neutral_impact	0,72	neutral	0,75	neutral	0,97	deleterious	0,15	4,14	0,38	0,55	neutral	0,34	neutral	0,17	neutral	0,23	neutral	0,28	4	neutral	0,38	deleterious	0,81	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,3	medium_impact	-0,43	0,35	0,9	11,89	12,5	N	0,43	N	0,5	polymorphism	0,94	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7408	7408	A	G	MI.5099	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1505	502	Y	C	tAc/tGc	1,91	0,95	0	possibly_damaging	0,81	neutral	0,14	neutral	2,93	neutral	-1,37	neutral	-0,62	medium_impact	2,82	neutral	0,64	neutral	0,32	deleterious	2,99	22,2	0,37	0,55	disease	0,63	disease	0,65	neutral	0,4	disease	0,51	0	neutral	0,92	neutral	0,17	NA	0	deleterious	0,65	low_impact	-1,35	medium_impact	-0,25	medium_impact	1,51	0,11	0,9	11,89	12,5	N	0,42	N	0,89	disease_causing	0,55	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8548	8548	T	C	MI.51	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	22	8	S	P	Tca/Cca	-0,1	0,83	0	benign	0	neutral	0,16	neutral	4,59	neutral	-1,94	neutral	-1,27	low_impact	1,84	neutral	0,95	neutral	0,86	deleterious	0,64	8,41	0,22	0,65	disease	0,8	disease	0,84	disease	0,57	disease	0,67	3	neutral	0,84	deleterious	0,58	neutral	-6	neutral	0,33	high_impact	2,09	medium_impact	-0,12	medium_impact	0,48	0,74	0,9	21,24	17,86	N	0,3	N	0,05	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8764	8764	G	A	MI.510	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	238	80	A	T	Gcc/Acc	-7,51	0	0,02	benign	0,01	neutral	0,05	neutral	4,37	neutral	-1,01	neutral	-1,22	neutral_impact	0,12	neutral	0,98	neutral	0,83	neutral	0,96	10,43	0,5	0,65	neutral	0,41	neutral	0,22	neutral	0,24	neutral	0,39	2	neutral	0,95	deleterious	0,52	neutral	-6	neutral	0,15	medium_impact	1,14	medium_impact	-0,43	medium_impact	-1	0,62	0,9	25,66	23,52	N	0,53	P	0,04	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7410	7410	C	G	MI.5100	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1507	503	H	D	Cac/Gac	-2,94	0	0	probably_damaging	0,97	deleterious	0,04	neutral	2,69	deleterious	-4,06	neutral	-2,36	high_impact	4,37	neutral	0,65	damaging	0,12	deleterious	3,99	23,6	0,28	0,55	disease	0,53	disease	0,8	disease	0,81	disease	0,76	5	deleterious	0,99	neutral	0,04	deleterious	6	deleterious	0,75	low_impact	-2,18	medium_impact	-0,58	high_impact	2,94	0,45	0,9	NA	NA	N	0,48	N	0,97	disease_causing	0,98	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7410	7410	C	A	MI.5101	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1507	503	H	N	Cac/Aac	-2,94	0	0	probably_damaging	0,95	deleterious	0,03	neutral	2,68	deleterious	-4,8	neutral	-1,84	high_impact	4,71	neutral	0,61	damaging	0,11	deleterious	4,14	23,8	0,55	0,6	disease	0,51	disease	0,82	disease	0,76	disease	0,76	5	deleterious	0,99	neutral	0,04	deleterious	6	deleterious	0,74	low_impact	-1,96	medium_impact	-0,65	high_impact	3,25	0,45	0,9	NA	NA	P	0,67	P	0,87	disease_causing	0,95	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7410	7410	C	T	MI.5102	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1507	503	H	Y	Cac/Tac	-2,94	0	0	probably_damaging	0,93	deleterious	0	neutral	2,76	deleterious	-6,83	neutral	-1,58	high_impact	4,37	neutral	0,66	damaging	0,11	deleterious	3,82	23,4	0,54	0,6	neutral	0,2	disease	0,83	disease	0,79	disease	0,77	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,7	low_impact	-1,81	low_impact	-1,48	high_impact	2,94	0,32	0,9	NA	NA	N	0,49	N	0,72	disease_causing	0,96	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7411	7411	A	G	MI.5103	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1508	503	H	R	cAc/cGc	5,6	1	0	probably_damaging	0,93	deleterious	0	neutral	2,69	deleterious	-5,14	neutral	-2,1	high_impact	4,16	neutral	0,65	damaging	0,12	deleterious	3,11	22,5	0,55	0,6	neutral	0,49	disease	0,82	disease	0,76	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,77	low_impact	-1,81	low_impact	-1,48	high_impact	2,74	0,37	0,9	NA	NA	P	0,5	N	0,85	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7411	7411	A	C	MI.5104	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1508	503	H	P	cAc/cCc	5,6	1	0	probably_damaging	0,98	deleterious	0	neutral	2,66	deleterious	-6,41	deleterious	-2,63	high_impact	4,71	damaging	0,59	damaging	0,13	deleterious	3,38	22,9	0,3	0,55	disease	0,68	disease	0,83	disease	0,78	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,35	low_impact	-1,48	high_impact	3,25	0,25	0,9	NA	NA	P	0,68	P	0,88	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7411	7411	A	T	MI.5105	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1508	503	H	L	cAc/cTc	5,6	1	0	probably_damaging	0,93	deleterious	0	neutral	2,72	deleterious	-6,21	deleterious	-2,88	high_impact	4,71	neutral	0,68	damaging	0,13	deleterious	4,01	23,6	0,32	0,55	neutral	0,29	disease	0,87	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,72	low_impact	-1,81	low_impact	-1,48	high_impact	3,25	0,3	0,9	NA	NA	P	0,66	P	0,91	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7412	7412	C	G	MI.5106	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1509	503	H	Q	caC/caG	6,98	1	0	probably_damaging	0,96	deleterious	0	neutral	2,67	deleterious	-5,05	neutral	-2,1	high_impact	4,37	neutral	0,61	damaging	0,15	deleterious	3,64	23,2	0,57	0,6	neutral	0,48	disease	0,76	disease	0,76	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-2,06	low_impact	-1,48	high_impact	2,94	0,39	0,9	NA	NA	P	0,51	P	0,84	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7412	7412	C	A	MI.5107	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1509	503	H	Q	caC/caA	6,98	1	0	probably_damaging	0,96	deleterious	0	neutral	2,67	deleterious	-5,05	neutral	-2,1	high_impact	4,37	neutral	0,61	damaging	0,15	deleterious	3,97	23,6	0,57	0,6	neutral	0,48	disease	0,76	disease	0,76	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,74	low_impact	-2,06	low_impact	-1,48	high_impact	2,94	0,39	0,9	NA	NA	P	0,51	P	0,84	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7413	7413	A	G	MI.5108	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1510	504	T	A	Aca/Gca	-0,4	0,35	0	probably_damaging	0,94	deleterious	0	neutral	2,96	neutral	0,1	neutral	-0,54	medium_impact	2,8	damaging	0,5	damaging	0,1	deleterious	3,53	23,1	0,6	0,65	neutral	0,23	neutral	0,3	neutral	0,46	neutral	0,45	1	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,61	low_impact	-1,88	low_impact	-1,48	medium_impact	1,49	0,5	0,9	NA	NA	N	0,41	N	0,65	disease_causing	0,83	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7413	7413	A	C	MI.5109	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1510	504	T	P	Aca/Cca	-0,4	0,35	0	probably_damaging	0,99	deleterious	0	neutral	2,94	neutral	-2,12	neutral	-0,94	high_impact	3,95	damaging	0,47	damaging	0,09	deleterious	3,63	23,2	0,19	0,55	disease	0,51	disease	0,69	disease	0,53	disease	0,63	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-2,64	low_impact	-1,48	high_impact	2,55	0,56	0,9	NA	NA	N	0,36	N	0,91	disease_causing	0,96	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8764	8764	G	T	MI.511	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	238	80	A	S	Gcc/Tcc	-7,51	0	0,02	benign	0,19	deleterious	0,04	neutral	4,36	neutral	-1,6	neutral	-0,89	neutral_impact	-0,04	neutral	0,88	neutral	0,91	deleterious	0,64	8,45	0,4	0,65	disease	0,57	neutral	0,3	neutral	0,4	disease	0,57	1	neutral	0,95	neutral	0,43	neutral	-2	neutral	0,24	medium_impact	-0,16	medium_impact	-0,49	low_impact	-1,13	0,72	0,9	25,66	23,52	N	0,46	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7413	7413	A	T	MI.5110	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1510	504	T	S	Aca/Tca	-0,4	0,35	0	probably_damaging	0,94	neutral	0,56	neutral	3,22	neutral	3,82	neutral	0,02	low_impact	1,07	damaging	0,55	damaging	0,18	neutral	0,94	10,33	0,53	0,6	neutral	0,22	neutral	0,04	neutral	0,16	neutral	0,25	5	neutral	0,93	neutral	0,31	neutral	-2	deleterious	0,58	low_impact	-1,88	medium_impact	0,25	medium_impact	-0,11	0,51	0,9	NA	NA	N	0,41	N	0,77	disease_causing	0,63	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7414	7414	C	T	MI.5111	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1511	504	T	M	aCa/aTa	8,59	1	0	probably_damaging	1	deleterious	0	neutral	2,89	neutral	-1,78	neutral	-0,93	medium_impact	3,15	damaging	0,54	damaging	0,1	deleterious	4,19	23,8	0,42	0,55	disease	0,6	neutral	0,42	disease	0,59	disease	0,66	3	deleterious	1	neutral	0	deleterious	5	deleterious	0,68	low_impact	-3,58	low_impact	-1,48	medium_impact	1,81	0,74	0,9	NA	NA	P	0,49	N	0,95	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7414	7414	C	A	MI.5112	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1511	504	T	K	aCa/aAa	8,59	1	0	probably_damaging	1	deleterious	0	neutral	2,97	neutral	-1,4	neutral	-0,78	high_impact	3,6	damaging	0,5	damaging	0,08	deleterious	4,7	24,6	0,4	0,55	neutral	0,24	disease	0,6	disease	0,63	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,68	low_impact	-3,58	low_impact	-1,48	high_impact	2,23	0,74	0,9	NA	NA	P	0,51	P	0,87	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7416	7416	T	A	MI.5113	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1513	505	F	I	Ttc/Atc	-0,17	0,58	0	probably_damaging	0,99	deleterious	0	neutral	2,79	deleterious	-5,91	neutral	-1,07	medium_impact	3,12	neutral	0,66	damaging	0,17	deleterious	4,58	24,4	0,28	0,55	neutral	0,35	disease	0,54	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,69	low_impact	-2,64	low_impact	-1,48	medium_impact	1,78	0,48	0,9	NA	NA	N	0,34	N	0,87	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7416	7416	T	G	MI.5114	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1513	505	F	V	Ttc/Gtc	-0,17	0,58	0	probably_damaging	1	deleterious	0,01	neutral	2,79	deleterious	-5,81	neutral	-1,15	high_impact	3,58	neutral	0,64	damaging	0,16	deleterious	4,31	24	0,34	0,55	neutral	0,37	disease	0,74	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,71	low_impact	-3,58	medium_impact	-0,92	high_impact	2,21	0,32	0,9	NA	NA	N	0,31	N	0,84	disease_causing	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7416	7416	T	C	MI.5115	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1513	505	F	L	Ttc/Ctc	-0,17	0,58	0	probably_damaging	0,98	neutral	0,06	neutral	2,83	deleterious	-4,78	neutral	-1,06	medium_impact	2,88	neutral	0,69	damaging	0,2	deleterious	3,15	22,6	0,44	0,55	neutral	0,34	disease	0,55	disease	0,61	disease	0,51	0	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,69	low_impact	-2,35	medium_impact	-0,47	medium_impact	1,56	0,37	0,9	NA	NA	N	0,35	N	0,81	disease_causing	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7417	7417	T	C	MI.5116	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1514	505	F	S	tTc/tCc	7,44	1	0	probably_damaging	1	deleterious	0	neutral	2,76	deleterious	-6,45	neutral	-1,22	medium_impact	3,03	neutral	0,71	damaging	0,17	deleterious	4,44	24,2	0,37	0,55	disease	0,5	disease	0,68	disease	0,65	disease	0,68	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,78	low_impact	-3,58	low_impact	-1,48	medium_impact	1,7	0,28	0,9	NA	NA	N	0,45	N	0,85	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7417	7417	T	A	MI.5117	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1514	505	F	Y	tTc/tAc	7,44	1	0	probably_damaging	0,98	neutral	0,86	neutral	2,93	neutral	-2,62	neutral	0,42	neutral_impact	0,06	neutral	0,67	neutral	0,35	neutral	1,79	14,92	0,43	0,55	disease	0,52	neutral	0,08	neutral	0,34	neutral	0,28	4	deleterious	0,98	neutral	0,44	neutral	-2	deleterious	0,67	low_impact	-2,35	medium_impact	0,63	low_impact	-1,04	0,45	0,9	NA	NA	P	0,51	P	0,58	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7417	7417	T	G	MI.5118	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1514	505	F	C	tTc/tGc	7,44	1	0	probably_damaging	1	deleterious	0,01	neutral	2,72	deleterious	-7,96	neutral	-1,39	medium_impact	3,23	neutral	0,65	damaging	0,16	deleterious	4,24	23,9	0,25	0,55	disease	0,74	disease	0,75	disease	0,65	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,78	low_impact	-3,58	medium_impact	-0,92	medium_impact	1,88	0,21	0,9	NA	NA	N	0,44	N	0,91	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7418	7418	C	A	MI.5119	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1515	505	F	L	ttC/ttA	2,6	0,99	0	probably_damaging	0,98	neutral	0,06	neutral	2,83	deleterious	-4,78	neutral	-1,06	medium_impact	2,88	neutral	0,69	damaging	0,2	deleterious	3,68	23,3	0,44	0,55	neutral	0,34	disease	0,55	disease	0,61	disease	0,51	0	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,69	low_impact	-2,35	medium_impact	-0,47	medium_impact	1,56	0,37	0,9	NA	NA	N	0,51	P	0,81	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8765	8765	C	T	MI.512	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	239	80	A	V	gCc/gTc	-0,1	0	0	benign	0,19	neutral	0,24	neutral	4,42	neutral	0,55	neutral	-0,8	neutral_impact	-0,84	neutral	0,9	neutral	0,78	deleterious	0,51	7,49	0,42	0,65	neutral	0,38	neutral	0,35	neutral	0,25	neutral	0,47	1	neutral	0,72	deleterious	0,53	neutral	-6	neutral	0,25	medium_impact	-0,16	medium_impact	0,01	low_impact	-1,82	0,71	0,9	25,66	23,52	N	0,45	N	0,76	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7418	7418	C	G	MI.5120	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1515	505	F	L	ttC/ttG	2,6	0,99	0	probably_damaging	0,98	neutral	0,06	neutral	2,83	deleterious	-4,78	neutral	-1,06	medium_impact	2,88	neutral	0,69	damaging	0,2	deleterious	3,4	23	0,44	0,55	neutral	0,34	disease	0,55	disease	0,61	disease	0,51	0	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,69	low_impact	-2,35	medium_impact	-0,47	medium_impact	1,56	0,37	0,9	NA	NA	N	0,48	N	0,81	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7419	7419	G	C	MI.5121	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1516	506	E	Q	Gaa/Caa	-3,17	0	0	benign	0,12	neutral	0,4	neutral	2,93	neutral	-0,69	neutral	-0,19	medium_impact	2,83	neutral	0,65	neutral	0,54	deleterious	0,32	5,92	0,4	0,55	neutral	0,32	neutral	0,17	neutral	0,31	neutral	0,32	4	neutral	0,53	deleterious	0,64	neutral	-3	neutral	0,25	medium_impact	0,06	medium_impact	0,1	medium_impact	1,51	0,63	0,9	7,8	32,1	N	0,49	N	0,66	polymorphism	0,65	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7419	7419	G	A	MI.5122	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1516	506	E	K	Gaa/Aaa	-3,17	0	0	benign	0,1	neutral	0,24	neutral	2,96	neutral	-0,12	neutral	-0,27	medium_impact	2,72	neutral	0,62	neutral	0,57	neutral	1,44	13,02	0,35	0,55	neutral	0,22	neutral	0,34	neutral	0,5	neutral	0,45	1	neutral	0,73	deleterious	0,57	neutral	-3	neutral	0,28	medium_impact	0,14	medium_impact	-0,09	medium_impact	1,41	0,75	0,9	7,8	32,1	N	0,51	P	0,72	disease_causing	0,7	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7420	7420	A	C	MI.5123	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1517	506	E	A	gAa/gCa	6,06	1	0	benign	0,18	neutral	0,17	neutral	3,04	neutral	0,07	neutral	-0,49	medium_impact	2,33	neutral	0,63	neutral	0,64	deleterious	0,68	8,68	0,36	0,55	neutral	0,14	neutral	0,2	neutral	0,46	neutral	0,36	3	neutral	0,8	deleterious	0,5	neutral	-3	neutral	0,21	medium_impact	-0,14	medium_impact	-0,19	medium_impact	1,05	0,63	0,9	7,8	32,1	P	0,67	P	0,7	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7420	7420	A	G	MI.5124	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1517	506	E	G	gAa/gGa	6,06	1	0	benign	0,14	neutral	0,08	neutral	2,96	neutral	-1,01	neutral	-0,49	medium_impact	2,62	neutral	0,63	neutral	0,58	neutral	1,3	12,28	0,35	0,55	neutral	0,34	neutral	0,25	disease	0,51	neutral	0,46	1	neutral	0,91	deleterious	0,47	neutral	-3	neutral	0,33	medium_impact	-0,01	medium_impact	-0,4	medium_impact	1,32	0,44	0,9	7,8	32,1	P	0,68	P	0,67	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7420	7420	A	T	MI.5125	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1517	506	E	V	gAa/gTa	6,06	1	0	benign	0,25	neutral	0,1	neutral	2,93	neutral	-1,21	neutral	-0,83	medium_impact	2,72	neutral	0,61	neutral	0,5	neutral	1,34	12,48	0,31	0,55	neutral	0,49	neutral	0,41	neutral	0,5	neutral	0,43	1	neutral	0,88	neutral	0,43	neutral	-3	neutral	0,42	medium_impact	-0,31	medium_impact	-0,34	medium_impact	1,41	0,6	0,9	7,8	32,1	P	0,63	P	0,68	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7421	7421	A	C	MI.5126	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1518	506	E	D	gaA/gaC	8,59	1	0	benign	0	neutral	0,19	neutral	3	neutral	-0,49	neutral	-0,1	low_impact	1,86	neutral	0,62	neutral	0,58	deleterious	0,34	6,06	0,51	0,6	neutral	0,29	neutral	0,17	neutral	0,25	neutral	0,31	4	neutral	0,81	deleterious	0,6	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	-0,16	medium_impact	0,62	0,75	0,9	7,8	32,1	P	0,71	P	0,7	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7421	7421	A	T	MI.5127	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1518	506	E	D	gaA/gaT	8,59	1	0	benign	0	neutral	0,19	neutral	3	neutral	-0,49	neutral	-0,1	low_impact	1,86	neutral	0,62	neutral	0,58	deleterious	0,46	7,09	0,51	0,6	neutral	0,29	neutral	0,17	neutral	0,25	neutral	0,31	4	neutral	0,81	deleterious	0,6	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	-0,16	medium_impact	0,62	0,75	0,9	7,8	32,1	P	0,7	P	0,7	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7422	7422	G	C	MI.5128	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1519	507	E	Q	Gaa/Caa	0,52	0,99	0	probably_damaging	0,99	neutral	0,05	neutral	2,71	deleterious	-3,94	neutral	-0,34	medium_impact	3,15	damaging	0,49	neutral	0,67	deleterious	2,31	18,25	0,59	0,65	neutral	0,28	neutral	0,34	neutral	0,41	neutral	0,39	2	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,7	low_impact	-2,64	medium_impact	-0,52	medium_impact	1,81	0,94	0,95	8,38	26,27	P	0,61	P	0,11	disease_causing	0,99	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7422	7422	G	A	MI.5129	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1519	507	E	K	Gaa/Aaa	0,52	0,99	0	probably_damaging	1	deleterious	0,01	neutral	2,72	deleterious	-3,47	neutral	-0,61	high_impact	4,27	damaging	0,55	damaging	0,15	deleterious	4,68	24,6	0,55	0,6	neutral	0,21	disease	0,64	disease	0,7	disease	0,62	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,74	low_impact	-3,58	medium_impact	-0,92	high_impact	2,84	0,87	0,9	8,38	26,27	N	0,46	N	0,66	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8765	8765	C	G	MI.513	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	239	80	A	G	gCc/gGc	-0,1	0	0	benign	0,19	neutral	0,18	neutral	4,35	neutral	-2,55	neutral	-1,15	neutral_impact	0,05	neutral	0,85	neutral	0,97	deleterious	0,63	8,39	0,31	0,65	neutral	0,48	neutral	0,25	neutral	0,32	neutral	0,41	2	neutral	0,79	deleterious	0,5	neutral	-6	neutral	0,24	medium_impact	-0,16	medium_impact	-0,08	low_impact	-1,06	0,72	0,9	25,66	23,52	N	0,49	N	0,02	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7423	7423	A	T	MI.5130	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1520	507	E	V	gAa/gTa	4,21	1	0	probably_damaging	1	deleterious	0	neutral	2,73	deleterious	-4,05	neutral	-0,49	high_impact	4,07	damaging	0,56	damaging	0,17	deleterious	4,2	23,9	0,4	0,55	neutral	0,47	disease	0,72	disease	0,7	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,58	low_impact	-1,48	high_impact	2,66	0,84	0,9	8,38	26,27	N	0,49	N	0,78	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7423	7423	A	G	MI.5131	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1520	507	E	G	gAa/gGa	4,21	1	0	probably_damaging	1	deleterious	0,01	neutral	2,71	deleterious	-4,75	neutral	-1,14	high_impact	4,62	damaging	0,54	damaging	0,19	deleterious	4,33	24	0,47	0,55	disease	0,53	disease	0,54	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,75	low_impact	-3,58	medium_impact	-0,92	high_impact	3,17	0,77	0,9	8,38	26,27	P	0,57	P	0,54	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7423	7423	A	C	MI.5132	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1520	507	E	A	gAa/gCa	4,21	1	0	probably_damaging	1	deleterious	0,02	neutral	2,72	deleterious	-3,76	neutral	-0,75	high_impact	4,27	neutral	0,66	damaging	0,18	deleterious	3,77	23,4	0,55	0,6	neutral	0,36	neutral	0,49	disease	0,67	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,72	low_impact	-3,58	medium_impact	-0,75	high_impact	2,84	0,86	0,9	8,38	26,27	P	0,48	N	0,54	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7424	7424	A	C	MI.5133	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1521	507	E	D	gaA/gaC	6,75	1	0,01	probably_damaging	0,94	deleterious	0,01	neutral	2,72	deleterious	-3,76	neutral	-0,58	high_impact	3,58	neutral	0,63	damaging	0,16	deleterious	3,79	23,4	0,58	0,65	neutral	0,41	neutral	0,46	neutral	0,4	neutral	0,42	2	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,68	low_impact	-1,88	medium_impact	-0,92	high_impact	2,21	0,97	1	8,38	26,27	P	0,6	P	0,51	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7424	7424	A	T	MI.5134	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1521	507	E	D	gaA/gaT	6,75	1	0,01	probably_damaging	0,94	deleterious	0,01	neutral	2,72	deleterious	-3,76	neutral	-0,58	high_impact	3,58	neutral	0,63	damaging	0,16	deleterious	3,89	23,5	0,58	0,65	neutral	0,41	neutral	0,46	neutral	0,4	neutral	0,42	2	deleterious	1	neutral	0,04	deleterious	6	deleterious	0,68	low_impact	-1,88	medium_impact	-0,92	high_impact	2,21	0,97	1	8,38	26,27	P	0,6	P	0,51	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7425	7425	C	G	MI.5135	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1522	508	P	A	Ccc/Gcc	-0,63	0,02	0	benign	0	neutral	0,65	neutral	3,05	neutral	-1,79	neutral	-0,22	medium_impact	2,51	neutral	0,64	neutral	0,61	deleterious	0,19	4,6	0,42	0,55	neutral	0,4	neutral	0,2	neutral	0,38	neutral	0,3	4	neutral	0,35	deleterious	0,83	neutral	-3	neutral	0,12	high_impact	2,07	medium_impact	0,34	medium_impact	1,22	0,7	0,9	NA	NA	N	0,4	N	0,76	disease_causing	0,8	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7425	7425	C	A	MI.5136	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1522	508	P	T	Ccc/Acc	-0,63	0,02	0	benign	0,06	neutral	0,56	neutral	3,08	neutral	0,6	neutral	-0,06	low_impact	1,34	neutral	0,61	neutral	0,42	neutral	1,13	11,36	0,41	0,55	neutral	0,27	neutral	0,36	neutral	0,23	neutral	0,42	2	neutral	0,38	deleterious	0,75	neutral	-6	neutral	0,16	medium_impact	0,37	medium_impact	0,25	medium_impact	0,14	0,65	0,9	NA	NA	N	0,36	N	0,82	disease_causing	0,86	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7425	7425	C	T	MI.5137	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1522	508	P	S	Ccc/Tcc	-0,63	0,02	0	benign	0	neutral	0,49	neutral	3,03	neutral	-2,06	neutral	-0,29	medium_impact	2,23	neutral	0,61	neutral	0,56	deleterious	3,64	23,2	0,46	0,55	neutral	0,49	neutral	0,32	neutral	0,23	neutral	0,4	2	neutral	0,51	deleterious	0,75	neutral	-3	neutral	0,16	high_impact	2,07	medium_impact	0,18	medium_impact	0,96	0,28	0,9	NA	NA	N	0,46	N	0,84	disease_causing	0,86	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7426	7426	C	A	MI.5138	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1523	508	P	H	cCc/cAc	5,6	1	0	possibly_damaging	0,7	neutral	0,39	neutral	2,99	deleterious	-4,59	neutral	-0,59	medium_impact	3,21	neutral	0,62	neutral	0,36	deleterious	4,44	24,2	0,42	0,55	disease	0,71	neutral	0,41	neutral	0,31	disease	0,62	2	neutral	0,72	neutral	0,35	NA	0	deleterious	0,65	low_impact	-1,1	medium_impact	0,09	medium_impact	1,87	0,58	0,9	NA	NA	P	0,59	P	0,82	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7426	7426	C	G	MI.5139	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1523	508	P	R	cCc/cGc	5,6	1	0	benign	0,39	neutral	0,28	neutral	3	deleterious	-3,47	neutral	-0,47	medium_impact	3,21	damaging	0,57	neutral	0,44	deleterious	3,92	23,5	0,44	0,55	disease	0,61	neutral	0,5	disease	0,51	disease	0,54	1	neutral	0,67	neutral	0,45	neutral	-3	deleterious	0,58	medium_impact	-0,57	medium_impact	-0,04	medium_impact	1,87	0,56	0,9	NA	NA	P	0,6	P	0,87	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8765	8765	C	A	MI.514	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	239	80	A	D	gCc/gAc	-0,1	0	0	possibly_damaging	0,48	deleterious	0,01	neutral	4,34	deleterious	-3,48	deleterious	-2,78	low_impact	1,15	neutral	0,85	neutral	0,45	deleterious	2,78	21,3	0,18	0,65	disease	0,83	disease	0,67	disease	0,58	disease	0,72	4	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,57	medium_impact	-0,72	medium_impact	-0,84	medium_impact	-0,11	0,64	0,9	25,66	23,52	N	0,3	N	0,73	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7426	7426	C	T	MI.5140	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1523	508	P	L	cCc/cTc	5,6	1	0	benign	0,2	neutral	1	neutral	3,23	deleterious	-3,29	neutral	0,29	neutral_impact	0,62	damaging	0,57	neutral	0,5	neutral	1,54	13,53	0,44	0,55	neutral	0,14	neutral	0,26	neutral	0,27	neutral	0,38	2	neutral	0,2	deleterious	0,9	neutral	-6	neutral	0,29	medium_impact	-0,19	high_impact	1,86	medium_impact	-0,53	0,7	0,9	NA	NA	N	0,5	N	0,89	disease_causing	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7428	7428	G	C	MI.5141	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1525	509	V	L	Gta/Cta	-16,08	0	0	benign	0,01	neutral	0,25	neutral	2,97	neutral	-2,72	neutral	-0,08	low_impact	0,8	neutral	0,69	neutral	0,69	deleterious	0,65	8,5	0,65	0,7	neutral	0,2	neutral	0,08	neutral	0,25	neutral	0,16	7	neutral	0,75	deleterious	0,62	neutral	-6	neutral	0,05	medium_impact	1,12	medium_impact	-0,07	medium_impact	-0,36	0,68	0,9	11,7	13,89	N	0,55	P	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7428	7428	G	A	MI.5142	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1525	509	V	M	Gta/Ata	-16,08	0	0	benign	0,2	neutral	0,15	neutral	2,89	deleterious	-4,4	neutral	-0,03	low_impact	1,01	neutral	0,66	neutral	0,74	neutral	1,11	11,26	0,48	0,55	neutral	0,36	neutral	0,07	neutral	0,14	neutral	0,16	7	neutral	0,82	deleterious	0,48	neutral	-6	neutral	0,19	medium_impact	-0,19	medium_impact	-0,23	medium_impact	-0,17	0,79	0,9	11,7	13,89	P	0,6	P	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7428	7428	G	T	MI.5143	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1525	509	V	L	Gta/Tta	-16,08	0	0	benign	0,01	neutral	0,25	neutral	2,97	neutral	-2,72	neutral	-0,08	low_impact	0,8	neutral	0,69	neutral	0,69	deleterious	0,74	9,09	0,65	0,7	neutral	0,2	neutral	0,08	neutral	0,25	neutral	0,16	7	neutral	0,75	deleterious	0,62	neutral	-6	neutral	0,05	medium_impact	1,12	medium_impact	-0,07	medium_impact	-0,36	0,68	0,9	11,7	13,89	N	0,55	P	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7429	7429	T	A	MI.5144	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1526	509	V	E	gTa/gAa	-0,63	0	0	benign	0,02	deleterious	0,04	neutral	2,92	deleterious	-4,59	neutral	-0,22	low_impact	1,7	neutral	0,61	neutral	0,62	deleterious	2,01	16,26	0,34	0,55	neutral	0,31	neutral	0,3	neutral	0,4	neutral	0,42	2	neutral	0,96	deleterious	0,51	neutral	-2	neutral	0,12	medium_impact	0,83	medium_impact	-0,58	medium_impact	0,47	0,38	0,9	11,7	13,89	N	0,53	P	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7429	7429	T	C	MI.5145	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1526	509	V	A	gTa/gCa	-0,63	0	0	benign	0	neutral	0,85	neutral	2,97	neutral	-2,93	neutral	-0,03	neutral_impact	-0,78	neutral	0,75	neutral	0,97	neutral	-0,57	0,15	0,48	0,55	neutral	0,19	neutral	0,04	neutral	0,16	neutral	0,14	7	neutral	0,15	deleterious	0,93	neutral	-6	neutral	0,05	high_impact	2,07	medium_impact	0,61	low_impact	-1,82	0,44	0,9	11,7	13,89	N	0,45	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7429	7429	T	G	MI.5146	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1526	509	V	G	gTa/gGa	-0,63	0	0	benign	0,02	neutral	0,08	neutral	2,88	deleterious	-4,38	neutral	-0,24	low_impact	0,9	neutral	0,66	neutral	0,66	deleterious	2,26	17,89	0,29	0,55	neutral	0,38	neutral	0,19	neutral	0,45	neutral	0,33	3	neutral	0,92	deleterious	0,53	neutral	-6	neutral	0,09	medium_impact	0,83	medium_impact	-0,4	medium_impact	-0,27	0,54	0,9	11,7	13,89	N	0,5	N	0,3	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7431	7431	T	C	MI.5147	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1528	510	Y	H	Tac/Cac	-13,31	0	0	possibly_damaging	0,85	neutral	0,08	neutral	2,96	neutral	-1,28	neutral	-0,26	low_impact	0,8	neutral	0,73	neutral	0,85	deleterious	2,53	19,63	0,84	0,85	neutral	0,42	neutral	0,1	neutral	0,2	neutral	0,2	6	neutral	0,96	neutral	0,12	neutral	-3	deleterious	0,59	low_impact	-1,47	medium_impact	-0,4	medium_impact	-0,36	0,43	0,9	9,16	31,3	N	0,52	P	0,8	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7431	7431	T	G	MI.5148	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1528	510	Y	D	Tac/Gac	-13,31	0	0	possibly_damaging	0,9	deleterious	0,01	neutral	2,97	neutral	-1,05	neutral	-0,37	medium_impact	2,25	damaging	0,59	neutral	0,53	deleterious	4,15	23,8	0,55	0,6	neutral	0,41	neutral	0,29	neutral	0,48	neutral	0,43	1	deleterious	1	neutral	0,06	deleterious	4	deleterious	0,65	low_impact	-1,65	medium_impact	-0,92	medium_impact	0,98	0,46	0,9	9,16	31,3	N	0,46	N	0,87	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7431	7431	T	A	MI.5149	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1528	510	Y	N	Tac/Aac	-13,31	0	0	possibly_damaging	0,9	neutral	0,14	neutral	2,97	neutral	-0,86	neutral	-0,14	medium_impact	2,25	neutral	0,65	neutral	0,64	deleterious	4,26	23,9	0,5	0,6	neutral	0,35	neutral	0,2	neutral	0,42	neutral	0,32	4	neutral	0,95	neutral	0,12	NA	0	deleterious	0,63	low_impact	-1,65	medium_impact	-0,25	medium_impact	0,98	0,34	0,9	9,16	31,3	N	0,52	P	0,81	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8767	8767	A	C	MI.515	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	241	81	T	P	Aca/Cca	-9,36	0	0	possibly_damaging	0,68	neutral	0,11	neutral	4,28	neutral	-2,96	deleterious	-3,22	medium_impact	3,2	neutral	0,76	neutral	0,42	deleterious	3,16	22,6	0,12	0,65	disease	0,81	disease	0,85	disease	0,67	disease	0,77	5	neutral	0,9	neutral	0,22	NA	0	deleterious	0,77	low_impact	-1,07	medium_impact	-0,22	medium_impact	1,65	0,62	0,9	26,99	25,17	N	0,32	N	0,66	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7432	7432	A	T	MI.5150	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1529	510	Y	F	tAc/tTc	4,67	0,83	0	benign	0,01	neutral	1	neutral	3	neutral	-0,25	neutral	0,09	neutral_impact	-0,4	neutral	0,77	neutral	0,96	neutral	-1	0,02	0,53	0,6	neutral	0,18	neutral	0,03	neutral	0,18	neutral	0,2	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,07	medium_impact	1,12	high_impact	1,86	low_impact	-1,47	0,36	0,9	9,16	31,3	N	0,37	N	0,22	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7432	7432	A	C	MI.5151	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1529	510	Y	S	tAc/tCc	4,67	0,83	0	possibly_damaging	0,66	deleterious	0,04	neutral	3,02	neutral	-0,17	neutral	0	neutral_impact	0,68	neutral	0,65	neutral	0,67	deleterious	2,69	20,8	0,67	0,7	neutral	0,23	neutral	0,17	neutral	0,43	neutral	0,25	5	neutral	0,96	neutral	0,19	deleterious	1	deleterious	0,56	low_impact	-1,03	medium_impact	-0,58	medium_impact	-0,47	0,41	0,9	9,16	31,3	P	0,54	P	0,75	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7432	7432	A	G	MI.5152	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1529	510	Y	C	tAc/tGc	4,67	0,83	0	probably_damaging	0,93	deleterious	0,01	neutral	2,94	neutral	-2,45	neutral	-0,11	low_impact	1,9	damaging	0,59	neutral	0,54	deleterious	3,7	23,3	0,68	0,7	neutral	0,46	neutral	0,25	neutral	0,28	neutral	0,43	1	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,62	low_impact	-1,81	medium_impact	-0,92	medium_impact	0,66	0,15	0,9	9,16	31,3	P	0,53	P	0,7	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7434	7434	A	G	MI.5153	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1531	511	M	V	Ata/Gta	-6,63	0	0	benign	0	neutral	1	neutral	3,14	neutral	1,85	neutral	0,15	neutral_impact	-1,68	neutral	0,81	neutral	0,98	neutral	-1,66	0	0,73	0,75	neutral	0,32	neutral	0,03	neutral	0,23	neutral	0,08	8	neutral	0	deleterious	1	neutral	-6	neutral	0,06	high_impact	2,07	high_impact	1,86	low_impact	-2,65	0,32	0,9	NA	NA	N	0,29	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7434	7434	A	T	MI.5154	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1531	511	M	L	Ata/Tta	-6,63	0	0	benign	0	neutral	0,47	neutral	3,19	neutral	1,99	neutral	0,15	neutral_impact	-1,23	neutral	0,67	neutral	0,81	deleterious	0,32	5,86	0,67	0,7	neutral	0,14	neutral	0,08	neutral	0,2	neutral	0,1	8	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,16	low_impact	-2,24	0,34	0,9	NA	NA	N	0,49	N	0,16	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7434	7434	A	C	MI.5155	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1531	511	M	L	Ata/Cta	-6,63	0	0	benign	0	neutral	0,47	neutral	3,19	neutral	1,99	neutral	0,15	neutral_impact	-1,23	neutral	0,67	neutral	0,81	deleterious	0,28	5,54	0,67	0,7	neutral	0,14	neutral	0,08	neutral	0,2	neutral	0,1	8	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,16	low_impact	-2,24	0,34	0,9	NA	NA	N	0,49	N	0,16	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7435	7435	T	A	MI.5156	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1532	511	M	K	aTa/aAa	0,06	0,02	0	benign	0,03	deleterious	0	neutral	2,98	neutral	0,08	neutral	-0,41	low_impact	1,1	neutral	0,65	neutral	0,68	deleterious	2,39	18,76	0,37	0,55	neutral	0,37	neutral	0,25	neutral	0,48	neutral	0,4	2	deleterious	1	deleterious	0,49	neutral	-2	neutral	0,15	medium_impact	0,66	low_impact	-1,48	medium_impact	-0,08	0,43	0,9	NA	NA	N	0,5	N	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7435	7435	T	C	MI.5157	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1532	511	M	T	aTa/aCa	0,06	0,02	0	benign	0,01	deleterious	0	neutral	2,99	neutral	0,23	neutral	0,05	neutral_impact	0,2	neutral	0,64	neutral	0,78	neutral	1,36	12,56	0,62	0,65	neutral	0,24	neutral	0,14	neutral	0,28	neutral	0,15	7	deleterious	1	deleterious	0,5	neutral	-2	neutral	0,09	medium_impact	1,12	low_impact	-1,48	medium_impact	-0,91	0,1	0,9	NA	NA	P	0,55	P	0,17	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7436	7436	A	C	MI.5158	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1533	511	M	I	atA/atC	4,67	0,69	0	benign	0	neutral	0,47	neutral	3,12	neutral	1,74	neutral	0,19	neutral_impact	-1,1	neutral	0,81	neutral	0,99	deleterious	0,16	4,23	0,71	0,75	neutral	0,28	neutral	0,04	neutral	0,23	neutral	0,11	8	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,16	low_impact	-2,12	0,33	0,9	NA	NA	N	0,46	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7436	7436	A	T	MI.5159	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1533	511	M	I	atA/atT	4,67	0,69	0	benign	0	neutral	0,47	neutral	3,12	neutral	1,74	neutral	0,19	neutral_impact	-1,1	neutral	0,81	neutral	0,99	deleterious	0,23	5,03	0,71	0,75	neutral	0,28	neutral	0,04	neutral	0,23	neutral	0,11	8	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,16	low_impact	-2,12	0,33	0,9	NA	NA	N	0,47	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8767	8767	A	T	MI.516	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	241	81	T	S	Aca/Tca	-9,36	0	0	benign	0,03	neutral	0,64	neutral	4,38	neutral	-0,83	neutral	-0,33	neutral_impact	-0,14	neutral	0,86	neutral	0,94	neutral	-1,36	0	0,48	0,65	neutral	0,43	neutral	0,15	neutral	0,31	neutral	0,25	5	neutral	0,31	deleterious	0,81	neutral	-6	neutral	0,16	medium_impact	0,68	medium_impact	0,43	low_impact	-1,22	0,62	0,9	26,99	25,17	N	0,35	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7437	7437	A	G	MI.5160	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1534	512	K	E	Aaa/Gaa	-13,77	0	0	probably_damaging	0,98	deleterious	0,04	neutral	2,96	neutral	-0,56	neutral	-0,09	low_impact	1,04	neutral	0,67	neutral	0,33	deleterious	3,18	22,7	0,39	0,55	neutral	0,12	neutral	0,25	neutral	0,39	neutral	0,33	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,63	low_impact	-2,35	medium_impact	-0,58	medium_impact	-0,14	0,67	0,9	7,6	59,6	N	0,43	N	0,4	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7437	7437	A	C	MI.5161	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1534	512	K	Q	Aaa/Caa	-13,77	0	0	probably_damaging	0,99	neutral	1	neutral	2,92	neutral	-1,05	neutral	-0,02	neutral_impact	-1,1	neutral	0,64	neutral	0,61	neutral	1	10,69	0,4	0,55	neutral	0,24	neutral	0,06	neutral	0,24	neutral	0,14	7	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,61	low_impact	-2,64	high_impact	1,86	low_impact	-2,12	0,72	0,9	7,6	59,6	N	0,33	N	0,48	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7438	7438	A	C	MI.5162	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1535	512	K	T	aAa/aCa	2,6	0,87	0	probably_damaging	0,99	neutral	0,32	neutral	2,93	neutral	-1,02	neutral	0,31	neutral_impact	-0,66	neutral	0,7	neutral	0,77	deleterious	2,67	20,6	0,35	0,55	neutral	0,31	neutral	0,2	neutral	0,38	neutral	0,27	5	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,65	low_impact	-2,64	medium_impact	0,01	low_impact	-1,71	0,59	0,9	7,6	59,6	N	0,44	N	0,48	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7438	7438	A	T	MI.5163	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1535	512	K	M	aAa/aTa	2,6	0,87	0	probably_damaging	1	deleterious	0,01	neutral	2,87	neutral	-2,45	neutral	0,1	neutral_impact	0,14	neutral	0,68	neutral	0,37	deleterious	4,02	23,6	0,26	0,55	disease	0,59	neutral	0,15	neutral	0,28	neutral	0,21	6	deleterious	1	neutral	0,01	deleterious	2	deleterious	0,66	low_impact	-3,58	medium_impact	-0,92	medium_impact	-0,97	0,51	0,9	7,6	59,6	N	0,44	N	0,58	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7439	7439	A	C	MI.5164	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1536	512	K	N	aaA/aaC	3,75	0,88	0	probably_damaging	0,99	neutral	0,09	neutral	2,92	neutral	-1,17	neutral	0,22	neutral_impact	-0,11	neutral	0,72	neutral	0,94	deleterious	2,98	22,2	0,58	0,65	neutral	0,26	neutral	0,13	neutral	0,39	neutral	0,17	7	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,63	low_impact	-2,64	medium_impact	-0,37	low_impact	-1,2	0,74	0,9	7,6	59,6	P	0,5	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7439	7439	A	T	MI.5165	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1536	512	K	N	aaA/aaT	3,75	0,88	0	probably_damaging	0,99	neutral	0,09	neutral	2,92	neutral	-1,17	neutral	0,22	neutral_impact	-0,11	neutral	0,72	neutral	0,94	deleterious	3,06	22,4	0,58	0,65	neutral	0,26	neutral	0,13	neutral	0,39	neutral	0,17	7	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,63	low_impact	-2,64	medium_impact	-0,37	low_impact	-1,2	0,74	0,9	7,6	59,6	P	0,52	P	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7440	7440	T	G	MI.5166	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1537	513	S	A	Tct/Gct	0,75	0,09	0	benign	0	neutral	0,22	neutral	3,01	neutral	0,19	neutral	-0,08	neutral_impact	0	neutral	0,81	neutral	0,97	deleterious	0,89	9,98	0,46	0,55	neutral	0,17	neutral	0,02	disease	0,51	neutral	0,11	8	neutral	0,78	deleterious	0,61	neutral	-6	neutral	0,03	high_impact	2,07	medium_impact	-0,11	low_impact	-1,1	0,7	0,9	NA	NA	N	0,52	P	0,03	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7440	7440	T	C	MI.5167	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1537	513	S	P	Tct/Cct	0,75	0,09	0	benign	0,02	deleterious	0,02	neutral	2,92	neutral	-1,32	neutral	-0,18	neutral_impact	0	damaging	0,53	damaging	0,23	deleterious	2,3	18,19	0,4	0,55	neutral	0,37	neutral	0,22	disease	0,56	neutral	0,27	5	neutral	0,98	deleterious	0,5	neutral	-2	neutral	0,04	medium_impact	0,83	medium_impact	-0,75	low_impact	-1,1	0,57	0,9	NA	NA	N	0,45	N	0,08	polymorphism	1	0,03	.	.	.	.	.	MNGIE fibroblasts	.	.	.	.	.	.	.	.	.
chrM	7440	7440	T	A	MI.5168	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1537	513	S	T	Tct/Act	0,75	0,09	0	benign	0	neutral	0,7	neutral	2,96	neutral	-0,47	neutral	-0,03	neutral_impact	0	neutral	0,81	neutral	0,98	neutral	-0,41	0,37	0,47	0,55	neutral	0,22	neutral	0,02	neutral	0,45	neutral	0,1	8	neutral	0,3	deleterious	0,85	neutral	-6	neutral	0,03	high_impact	2,07	medium_impact	0,4	low_impact	-1,1	0,74	0,9	NA	NA	N	0,46	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7441	7441	C	T	MI.5169	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1538	513	S	F	tCt/tTt	-2,48	0,01	0,01	benign	0,06	deleterious	0,01	neutral	2,93	neutral	-1,06	neutral	0,15	neutral_impact	0	neutral	0,64	damaging	0,25	deleterious	2,45	19,15	0,35	0,55	disease	0,51	neutral	0,12	disease	0,62	neutral	0,18	6	deleterious	0,99	deleterious	0,48	neutral	-2	neutral	0,12	medium_impact	0,37	medium_impact	-0,92	low_impact	-1,1	0,48	0,9	NA	NA	N	0,4	N	0,31	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8767	8767	A	G	MI.517	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	241	81	T	A	Aca/Gca	-9,36	0	0	benign	0,28	neutral	0,26	neutral	4,35	neutral	0,46	neutral	-1,67	low_impact	1,88	neutral	0,91	neutral	0,82	deleterious	0,45	7,07	0,68	0,75	neutral	0,35	neutral	0,42	neutral	0,48	neutral	0,47	1	neutral	0,69	deleterious	0,49	neutral	-6	neutral	0,33	medium_impact	-0,37	medium_impact	0,04	medium_impact	0,51	0,47	0,9	26,99	25,17	N	0,41	N	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7441	7441	C	A	MI.5170	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1538	513	S	Y	tCt/tAt	-2,48	0,01	0,01	benign	0,09	deleterious	0,01	neutral	2,92	neutral	-1,3	neutral	-0,03	neutral_impact	0	neutral	0,63	neutral	0,29	deleterious	2,44	19,05	0,37	0,55	neutral	0,48	neutral	0,13	disease	0,53	neutral	0,18	7	deleterious	0,99	neutral	0,46	neutral	-2	neutral	0,11	medium_impact	0,19	medium_impact	-0,92	low_impact	-1,1	0,66	0,9	NA	NA	N	0,41	N	0,24	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7441	7441	C	G	MI.5171	MT-CO1	IV	ENSG00000198804	ENSP00000354499	ENST00000361624	COX1_HUMAN	P00395	4512	YP_003024028.1	1538	513	S	C	tCt/tGt	-2,48	0,01	0,01	benign	0,12	neutral	0,08	neutral	2,9	neutral	-2,2	neutral	-0,21	neutral_impact	0	damaging	0,59	neutral	0,31	deleterious	1,82	15,12	0,42	0,55	disease	0,6	neutral	0,11	disease	0,59	neutral	0,17	7	neutral	0,91	deleterious	0,48	neutral	-6	neutral	0,14	medium_impact	0,06	medium_impact	-0,4	low_impact	-1,1	0,71	0,9	NA	NA	N	0,41	N	0,3	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7586	7586	A	C	MI.5172	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	1	1	M	L	Atg/Ctg	-3,4	0	0	possibly_damaging	0,9	deleterious	0	neutral	1,28	neutral	-2,12	deleterious	-2,87	NA	NA	damaging	0,16	damaging	0,02	deleterious	3,13	22,6	0,35	0,5	NA	NA	neutral	0,22	disease	0,56	neutral	0,37	3	deleterious	1	neutral	0,05	deleterious	3	deleterious	0,67	NA	NA	NA	NA	NA	NA	0,33	0,8	68,72	19,52	P	0,76	P	0,7	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7586	7586	A	G	MI.5173	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	1	1	M	V	Atg/Gtg	-3,4	0	0	probably_damaging	0,94	deleterious	0	neutral	1,25	neutral	-2,64	deleterious	-3,82	NA	NA	damaging	0,12	damaging	0,01	deleterious	2,51	19,52	0,49	0,55	NA	NA	neutral	0,29	disease	0,65	neutral	0,39	2	deleterious	1	neutral	0,03	deleterious	4	deleterious	0,7	NA	NA	NA	NA	NA	NA	0,46	0,8	68,72	19,52	P	0,74	P	0,89	NA	NA	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7586	7586	A	T	MI.5174	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	1	1	M	L	Atg/Ttg	-3,4	0	0	possibly_damaging	0,9	deleterious	0	neutral	1,28	neutral	-2,12	deleterious	-2,87	NA	NA	damaging	0,16	damaging	0,02	deleterious	3,1	22,5	0,35	0,5	NA	NA	neutral	0,22	disease	0,56	neutral	0,37	3	deleterious	1	neutral	0,05	deleterious	3	deleterious	0,67	NA	NA	NA	NA	NA	NA	0,33	0,8	68,72	19,52	P	0,76	P	0,7	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7587	7587	T	A	MI.5175	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	2	1	M	K	aTg/aAg	6,98	1	0	probably_damaging	0,97	deleterious	0	neutral	1,27	neutral	-2,18	deleterious	-5,73	NA	NA	damaging	0,15	damaging	0,01	deleterious	3,8	23,4	0,3	0,45	NA	NA	neutral	0,44	disease	0,67	neutral	0,43	1	deleterious	1	neutral	0,02	deleterious	4	deleterious	0,79	NA	NA	NA	NA	NA	NA	0,36	0,8	68,72	19,52	P	0,83	P	1	NA	NA	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7587	7587	T	C	MI.5176	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	2	1	M	T	aTg/aCg	6,98	1	0	probably_damaging	0,97	deleterious	0	neutral	1,24	neutral	-2,89	deleterious	-5,73	NA	NA	damaging	0,16	damaging	0,02	deleterious	2,73	21	0,37	0,5	NA	NA	neutral	0,39	disease	0,65	neutral	0,39	2	deleterious	1	neutral	0,02	deleterious	4	deleterious	0,79	NA	NA	NA	NA	NA	NA	0,22	0,8	68,72	19,52	P	0,79	P	0,92	NA	NA	0,23	rs199474825	Pathogenic	Cytochrome-c_oxidase_deficiency	RCV000010294.3	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	T7587C	Mitochondrial Encephalomyopathy	-	+	Reported	2
chrM	7588	7588	G	C	MI.5177	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	3	1	M	I	atG/atC	7,44	1	0	probably_damaging	0,96	deleterious	0	neutral	1,23	neutral	-2,92	deleterious	-3,82	NA	NA	damaging	0,16	damaging	0,01	deleterious	3,33	22,9	0,46	0,55	NA	NA	neutral	0,32	disease	0,56	neutral	0,37	3	deleterious	1	neutral	0,02	deleterious	4	deleterious	0,75	NA	NA	NA	NA	NA	NA	0,59	0,8	68,72	19,52	P	0,84	P	0,78	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7588	7588	G	T	MI.5178	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	3	1	M	I	atG/atT	7,44	1	0	probably_damaging	0,96	deleterious	0	neutral	1,23	neutral	-2,92	deleterious	-3,82	NA	NA	damaging	0,16	damaging	0,01	deleterious	3,43	23	0,46	0,55	NA	NA	neutral	0,32	disease	0,56	neutral	0,37	3	deleterious	1	neutral	0,02	deleterious	4	deleterious	0,75	NA	NA	NA	NA	NA	NA	0,59	0,8	68,72	19,52	P	0,84	P	0,78	NA	NA	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7589	7589	G	A	MI.5179	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	4	2	A	T	Gca/Aca	7,44	1	0	possibly_damaging	0,66	neutral	0,52	neutral	1,44	neutral	-1,4	deleterious	-3,6	low_impact	1,52	damaging	0,47	neutral	0,39	deleterious	1,98	16,08	0,67	0,7	NA	NA	neutral	0,16	neutral	0,15	neutral	0,23	5	neutral	0,63	neutral	0,43	neutral	-3	deleterious	0,54	medium_impact	-0,99	medium_impact	0,22	medium_impact	0,32	0,7	0,85	67,4	14,6	P	0,66	P	0,86	disease_causing	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8768	8768	C	T	MI.518	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	242	81	T	M	aCa/aTa	-0,33	0	0	probably_damaging	0,93	neutral	0,31	neutral	4,34	neutral	-1,05	deleterious	-2,61	low_impact	1,32	neutral	0,8	neutral	0,64	deleterious	2,68	20,7	0,41	0,65	disease	0,5	neutral	0,43	neutral	0,39	neutral	0,2	6	neutral	0,94	neutral	0,19	neutral	-2	deleterious	0,68	low_impact	-1,82	medium_impact	0,1	medium_impact	0,03	0,76	0,9	26,99	25,17	N	0,31	N	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7589	7589	G	T	MI.5180	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	4	2	A	S	Gca/Tca	7,44	1	0	possibly_damaging	0,45	neutral	0,75	neutral	1,58	neutral	-0,01	deleterious	-2,56	low_impact	1,1	damaging	0,49	neutral	0,45	deleterious	0,62	8,29	0,55	0,6	NA	NA	neutral	0,11	neutral	0,11	neutral	0,27	5	neutral	0,34	deleterious	0,65	neutral	-3	neutral	0,35	medium_impact	-0,64	medium_impact	0,47	medium_impact	-0,07	0,77	0,85	67,4	14,6	P	0,57	P	0,48	disease_causing	0,94	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7589	7589	G	C	MI.5181	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	4	2	A	P	Gca/Cca	7,44	1	0	benign	0,04	neutral	0,33	neutral	1,53	neutral	-0,42	deleterious	-4,49	low_impact	1,43	damaging	0,58	neutral	0,66	deleterious	0,55	7,84	0,38	0,5	NA	NA	neutral	0,38	neutral	0,13	neutral	0,2	6	neutral	0,65	deleterious	0,65	neutral	-6	neutral	0,19	medium_impact	0,57	medium_impact	0,04	medium_impact	0,24	0,72	0,85	67,4	14,6	P	0,58	P	0,51	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7590	7590	C	G	MI.5182	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	5	2	A	G	gCa/gGa	2,37	1	0	benign	0,37	neutral	0,33	neutral	1,39	neutral	-2,51	deleterious	-3,64	medium_impact	3,04	damaging	0,44	neutral	0,52	deleterious	1,9	15,58	0,55	0,6	NA	NA	neutral	0,26	neutral	0,39	neutral	0,2	6	neutral	0,61	deleterious	0,48	neutral	-3	neutral	0,29	medium_impact	-0,51	medium_impact	0,04	medium_impact	1,75	0,79	0,85	67,4	14,6	P	0,67	P	0,71	disease_causing	0,94	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7590	7590	C	A	MI.5183	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	5	2	A	E	gCa/gAa	2,37	1	0	possibly_damaging	0,83	neutral	0,7	neutral	1,45	neutral	-1,32	deleterious	-4,55	medium_impact	2,29	damaging	0,37	neutral	0,31	deleterious	3,84	23,4	0,45	0,55	NA	NA	neutral	0,43	neutral	0,47	neutral	0,24	5	neutral	0,8	neutral	0,44	NA	0	deleterious	0,65	low_impact	-1,36	medium_impact	0,41	medium_impact	1,04	0,62	0,8	67,4	14,6	P	0,75	P	0,9	disease_causing	0,97	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7590	7590	C	T	MI.5184	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	5	2	A	V	gCa/gTa	2,37	1	0	possibly_damaging	0,61	neutral	0,34	neutral	1,39	neutral	-2,51	deleterious	-3,75	medium_impact	2,92	damaging	0,41	neutral	0,39	deleterious	2,48	19,36	0,62	0,65	NA	NA	neutral	0,31	neutral	0,42	neutral	0,19	6	neutral	0,69	neutral	0,37	NA	0	deleterious	0,57	medium_impact	-0,9	medium_impact	0,05	medium_impact	1,63	0,69	0,85	67,4	14,6	P	0,73	P	0,76	disease_causing	0,96	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7592	7592	C	G	MI.5185	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	7	3	H	D	Cat/Gat	-6,63	0	0	probably_damaging	0,99	neutral	0,2	neutral	1,58	neutral	-0,24	deleterious	-5,96	low_impact	1,62	damaging	0,55	damaging	0,21	deleterious	3,68	23,3	0,52	0,6	NA	NA	neutral	0,4	neutral	0,39	neutral	0,16	7	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,74	low_impact	-2,58	medium_impact	-0,13	medium_impact	0,41	0,44	0,8	31,72	63,41	N	0,33	N	0,86	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7592	7592	C	A	MI.5186	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	7	3	H	N	Cat/Aat	-6,63	0	0	probably_damaging	0,99	neutral	0,34	neutral	1,6	neutral	0,3	deleterious	-4,36	low_impact	1,21	neutral	0,74	neutral	0,62	deleterious	2,36	18,55	0,72	0,75	NA	NA	neutral	0,26	neutral	0,25	neutral	0,18	6	deleterious	0,99	neutral	0,18	neutral	-2	deleterious	0,7	low_impact	-2,58	medium_impact	0,05	medium_impact	0,03	0,46	0,8	31,72	63,41	N	0,37	N	0,73	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7592	7592	C	T	MI.5187	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	7	3	H	Y	Cat/Tat	-6,63	0	0	probably_damaging	0,99	neutral	1	neutral	1,58	neutral	-0,22	neutral	-1,82	neutral_impact	0,76	neutral	0,78	neutral	0,97	neutral	1,65	14,13	0,6	0,65	NA	NA	neutral	0,19	neutral	0,16	neutral	0,19	6	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,72	low_impact	-2,58	high_impact	1,86	medium_impact	-0,39	0,35	0,8	31,72	63,41	N	0,32	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7593	7593	A	C	MI.5188	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	8	3	H	P	cAt/cCt	2,14	0,97	0	probably_damaging	1	neutral	0,2	neutral	1,56	neutral	-0,99	deleterious	-6,68	low_impact	0,99	damaging	0,48	damaging	0,17	deleterious	2,98	22,2	0,47	0,55	NA	NA	disease	0,61	neutral	0,34	disease	0,5	0	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,78	low_impact	-3,52	medium_impact	-0,13	medium_impact	-0,18	0,24	0,8	31,72	63,41	N	0,45	N	0,93	polymorphism	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7593	7593	A	T	MI.5189	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	8	3	H	L	cAt/cTt	2,14	0,97	0	probably_damaging	0,99	neutral	0,65	neutral	1,69	neutral	1,73	deleterious	-6,72	low_impact	0,9	damaging	0,59	damaging	0,27	deleterious	2,37	18,66	0,34	0,5	NA	NA	neutral	0,31	neutral	0,31	neutral	0,17	7	deleterious	0,99	neutral	0,33	neutral	-2	deleterious	0,71	low_impact	-2,58	medium_impact	0,35	medium_impact	-0,26	0,36	0,8	31,72	63,41	N	0,35	N	0,79	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8768	8768	C	A	MI.519	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	242	81	T	K	aCa/aAa	-0,33	0	0	benign	0,39	neutral	0,15	neutral	4,29	neutral	-2,36	deleterious	-2,7	medium_impact	3,2	neutral	0,79	neutral	0,51	deleterious	2,69	20,7	0,19	0,65	disease	0,75	disease	0,8	disease	0,65	disease	0,74	5	neutral	0,82	neutral	0,38	neutral	-3	deleterious	0,56	medium_impact	-0,57	medium_impact	-0,13	medium_impact	1,65	0,74	0,9	26,99	25,17	N	0,3	N	0,52	polymorphism	1	0,28	rs386829048	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7593	7593	A	G	MI.5190	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	8	3	H	R	cAt/cGt	2,14	0,97	0	probably_damaging	0,99	neutral	0,33	neutral	1,59	neutral	0,13	deleterious	-5,13	low_impact	1,7	damaging	0,51	damaging	0,21	neutral	1,57	13,71	0,7	0,75	NA	NA	neutral	0,36	neutral	0,33	neutral	0,16	7	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,76	low_impact	-2,58	medium_impact	0,04	medium_impact	0,49	0,24	0,8	31,72	63,41	N	0,46	N	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7594	7594	T	G	MI.5191	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	9	3	H	Q	caT/caG	6,75	0,99	0	probably_damaging	1	neutral	0,29	neutral	1,59	neutral	0,21	deleterious	-4,56	low_impact	1,07	neutral	0,67	neutral	0,42	deleterious	2,22	17,62	0,76	0,8	NA	NA	neutral	0,18	neutral	0,23	neutral	0,22	6	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,7	low_impact	-3,52	medium_impact	-0,01	medium_impact	-0,1	0,29	0,8	31,72	63,41	P	0,57	P	0,61	polymorphism	0,87	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7594	7594	T	A	MI.5192	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	9	3	H	Q	caT/caA	6,75	0,99	0	probably_damaging	1	neutral	0,29	neutral	1,59	neutral	0,21	deleterious	-4,56	low_impact	1,07	neutral	0,67	neutral	0,42	deleterious	2,43	18,99	0,76	0,8	NA	NA	neutral	0,18	neutral	0,23	neutral	0,22	6	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,7	low_impact	-3,52	medium_impact	-0,01	medium_impact	-0,1	0,29	0,8	31,72	63,41	P	0,58	P	0,61	polymorphism	0,87	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7595	7595	G	A	MI.5193	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	10	4	A	T	Gca/Aca	-1,55	0	0	benign	0	neutral	0,4	neutral	1,57	neutral	-0,36	neutral	-0,1	low_impact	0,9	neutral	0,72	neutral	0,59	deleterious	0,46	7,13	0,5	0,6	NA	NA	neutral	0,15	neutral	0,35	neutral	0,26	5	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,15	high_impact	2,08	medium_impact	0,11	medium_impact	-0,26	0,62	0,8	67,4	12,96	N	0,44	N	0,55	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7595	7595	G	T	MI.5194	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	10	4	A	S	Gca/Tca	-1,55	0	0	benign	0,09	neutral	0,41	neutral	1,59	neutral	0,1	neutral	0,13	neutral_impact	-0,42	neutral	0,7	neutral	0,76	neutral	-0,07	1,99	0,36	0,5	NA	NA	neutral	0,17	neutral	0,18	neutral	0,25	5	neutral	0,53	deleterious	0,66	neutral	-6	neutral	0,2	medium_impact	0,22	medium_impact	0,12	low_impact	-1,5	0,55	0,8	67,4	12,96	N	0,52	P	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7595	7595	G	C	MI.5195	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	10	4	A	P	Gca/Cca	-1,55	0	0	benign	0	neutral	0,31	neutral	1,67	neutral	1,01	neutral	5,86	neutral_impact	-1,98	neutral	0,87	neutral	0,9	neutral	-0,94	0,02	0,28	0,45	NA	NA	neutral	0,12	neutral	0,15	neutral	0,24	5	neutral	0,69	deleterious	0,66	neutral	-6	neutral	0,17	high_impact	2,08	medium_impact	0,01	low_impact	-2,96	0,57	0,8	67,4	12,96	N	0,49	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7596	7596	C	A	MI.5196	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	11	4	A	E	gCa/gAa	3,52	0,88	0	benign	0,09	neutral	0,28	neutral	1,56	neutral	-0,4	neutral	-0,05	neutral_impact	0,55	neutral	0,64	neutral	0,59	deleterious	2,35	18,48	0,33	0,5	NA	NA	neutral	0,42	neutral	0,45	neutral	0,16	7	neutral	0,68	deleterious	0,6	neutral	-6	neutral	0,23	medium_impact	0,22	medium_impact	-0,02	medium_impact	-0,59	0,56	0,8	67,4	12,96	N	0,42	N	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7596	7596	C	T	MI.5197	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	11	4	A	V	gCa/gTa	3,52	0,88	0	benign	0,09	neutral	0,51	neutral	1,58	neutral	-0,06	neutral	-1,14	low_impact	0,9	neutral	0,69	neutral	0,72	neutral	1,36	12,56	0,4	0,5	NA	NA	neutral	0,22	neutral	0,36	neutral	0,15	7	neutral	0,42	deleterious	0,71	neutral	-6	neutral	0,19	medium_impact	0,22	medium_impact	0,21	medium_impact	-0,26	0,61	0,8	67,4	12,96	N	0,41	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7596	7596	C	G	MI.5198	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	11	4	A	G	gCa/gGa	3,52	0,88	0	benign	0,09	neutral	0,34	neutral	1,53	neutral	-1,42	neutral	-0,97	neutral_impact	0,55	neutral	0,65	neutral	0,62	deleterious	0,82	9,56	0,36	0,5	NA	NA	neutral	0,21	neutral	0,32	neutral	0,18	6	neutral	0,62	deleterious	0,63	neutral	-6	neutral	0,21	medium_impact	0,22	medium_impact	0,05	medium_impact	-0,59	0,71	0,85	67,4	12,96	N	0,46	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7598	7598	G	A	MI.5199	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	13	5	A	T	Gcg/Acg	-6,63	0	0,01	benign	0	neutral	0,56	neutral	1,54	neutral	-0,65	neutral	-0,14	low_impact	0,81	neutral	0,86	neutral	0,83	deleterious	0,5	7,45	0,67	0,7	NA	NA	neutral	0,15	neutral	0,3	neutral	0,24	5	neutral	0,44	deleterious	0,78	neutral	-6	neutral	0,09	high_impact	2,08	medium_impact	0,26	medium_impact	-0,35	0,73	0,85	32,16	66,12	N	0,4	N	0,31	polymorphism	1	0,01	rs386420012	.	.	.	.	.	.	.	.	G7598A	Possible LHON helper variant	-	+	Reported	1
chrM	8549	8549	C	G	MI.52	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	23	8	S	W	tCa/tGa	2,9	1	0	possibly_damaging	0,77	deleterious	0,03	neutral	4,57	deleterious	-4,19	deleterious	-3,29	low_impact	1,84	neutral	0,78	neutral	0,38	deleterious	3,89	23,5	0,23	0,65	disease	0,94	disease	0,84	disease	0,52	disease	0,84	7	neutral	0,98	neutral	0,13	deleterious	1	deleterious	0,78	low_impact	-1,25	medium_impact	-0,56	medium_impact	0,48	0,5	0,9	21,24	17,86	N	0,45	N	0,81	disease_causing	0,92	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8770	8770	A	C	MI.520	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	244	82	T	P	Act/Cct	-6,81	0	0	probably_damaging	1	neutral	0,06	neutral	4,31	neutral	-2,12	deleterious	-3,93	low_impact	1,94	neutral	0,77	damaging	0,09	deleterious	2,25	17,82	0,14	0,65	disease	0,72	disease	0,75	disease	0,66	disease	0,73	5	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,38	medium_impact	0,57	0,63	0,9	15,49	18,3	N	0,22	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7598	7598	G	T	MI.5200	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	13	5	A	S	Gcg/Tcg	-6,63	0	0,01	benign	0,07	neutral	0,91	neutral	1,58	neutral	-0,02	neutral	0,3	neutral_impact	-1	neutral	0,73	neutral	0,77	neutral	-0,97	0,02	0,49	0,55	NA	NA	neutral	0,04	neutral	0,2	neutral	0,19	6	neutral	0,03	deleterious	0,92	neutral	-6	neutral	0,11	medium_impact	0,33	medium_impact	0,76	low_impact	-2,04	0,81	0,85	32,16	66,12	N	0,35	N	0,34	polymorphism	1	0	rs386420012	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7598	7598	G	C	MI.5201	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	13	5	A	P	Gcg/Ccg	-6,63	0	0,01	benign	0,3	neutral	0,26	neutral	1,48	neutral	-2,55	neutral	-2,37	low_impact	1,32	damaging	0,56	neutral	0,37	neutral	1,06	10,98	0,33	0,5	NA	NA	disease	0,54	neutral	0,46	neutral	0,49	0	neutral	0,69	deleterious	0,48	neutral	-6	neutral	0,34	medium_impact	-0,38	medium_impact	-0,05	medium_impact	0,13	0,87	0,9	32,16	66,12	N	0,34	N	0,57	polymorphism	1	0,07	rs386420012	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7599	7599	C	G	MI.5202	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	14	5	A	G	gCg/gGg	-0,4	0	0	benign	0,07	neutral	0,5	neutral	1,53	neutral	-0,82	neutral	-1,98	neutral_impact	0,26	neutral	0,69	neutral	0,61	deleterious	0,52	7,59	0,46	0,55	NA	NA	neutral	0,16	neutral	0,27	neutral	0,23	5	neutral	0,44	deleterious	0,72	neutral	-6	neutral	0,15	medium_impact	0,33	medium_impact	0,21	medium_impact	-0,86	0,84	0,9	32,16	66,12	N	0,36	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7599	7599	C	A	MI.5203	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	14	5	A	E	gCg/gAg	-0,4	0	0	benign	0,11	neutral	0,55	neutral	1,52	neutral	-1,14	neutral	-1,98	low_impact	1,92	neutral	0,64	neutral	0,53	neutral	1,54	13,53	0,33	0,5	NA	NA	neutral	0,44	disease	0,55	neutral	0,41	2	neutral	0,36	deleterious	0,72	neutral	-6	neutral	0,23	medium_impact	0,13	medium_impact	0,25	medium_impact	0,7	0,66	0,8	32,16	66,12	N	0,31	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7599	7599	C	T	MI.5204	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	14	5	A	V	gCg/gTg	-0,4	0	0	benign	0	neutral	0,55	neutral	1,57	neutral	-0,19	neutral	-1,4	low_impact	1,92	neutral	0,83	neutral	0,75	neutral	1,08	11,12	0,51	0,6	NA	NA	neutral	0,24	neutral	0,48	neutral	0,19	6	neutral	0,45	deleterious	0,78	neutral	-6	neutral	0,11	high_impact	2,08	medium_impact	0,25	medium_impact	0,7	0,76	0,85	32,16	66,12	N	0,29	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7601	7601	C	A	MI.5205	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	16	6	Q	K	Caa/Aaa	-9,39	0	0	probably_damaging	1	neutral	0,33	neutral	1,44	neutral	-1,2	deleterious	-3,76	medium_impact	2,3	damaging	0,19	damaging	0,03	deleterious	3,95	23,6	0,59	0,65	NA	NA	neutral	0,44	disease	0,54	neutral	0,38	2	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,74	low_impact	-3,52	medium_impact	0,04	medium_impact	1,05	0,68	0,85	68,28	15,91	P	0,7	P	0,84	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7601	7601	C	G	MI.5206	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	16	6	Q	E	Caa/Gaa	-9,39	0	0	probably_damaging	0,98	neutral	0,29	neutral	1,45	neutral	-0,97	deleterious	-2,74	medium_impact	2,61	damaging	0,33	neutral	0,35	deleterious	3,01	22,3	0,65	0,7	NA	NA	neutral	0,33	disease	0,68	neutral	0,41	2	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,72	low_impact	-2,3	medium_impact	-0,01	medium_impact	1,34	0,71	0,85	68,28	15,91	P	0,58	P	0,28	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7602	7602	A	T	MI.5207	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	17	6	Q	L	cAa/cTa	2,83	0,98	0	probably_damaging	1	neutral	0,81	neutral	1,41	neutral	-2,79	deleterious	-6,65	medium_impact	2,52	damaging	0,29	damaging	0,05	deleterious	3,86	23,5	0,41	0,5	NA	NA	neutral	0,45	disease	0,65	neutral	0,47	1	deleterious	1	neutral	0,41	deleterious	1	deleterious	0,73	low_impact	-3,52	medium_impact	0,55	medium_impact	1,26	0,34	0,8	68,28	15,91	P	0,72	P	0,83	disease_causing	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7602	7602	A	G	MI.5208	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	17	6	Q	R	cAa/cGa	2,83	0,98	0	probably_damaging	1	neutral	0,35	neutral	1,41	neutral	-1,85	deleterious	-3,77	high_impact	3,96	damaging	0,21	damaging	0,06	deleterious	3,48	23,1	0,63	0,65	NA	NA	neutral	0,46	disease	0,71	neutral	0,49	0	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,76	low_impact	-3,52	medium_impact	0,06	high_impact	2,61	0,5	0,8	68,28	15,91	P	0,84	P	0,71	disease_causing	0,8	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7602	7602	A	C	MI.5209	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	17	6	Q	P	cAa/cCa	2,83	0,98	0	probably_damaging	1	neutral	0,24	neutral	1,4	deleterious	-3,52	deleterious	-5,68	high_impact	3,96	damaging	0,15	damaging	0,03	deleterious	3,39	23	0,35	0,5	NA	NA	disease	0,65	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,78	low_impact	-3,52	medium_impact	-0,07	high_impact	2,61	0,51	0,8	68,28	15,91	P	0,82	P	0,79	disease_causing	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8770	8770	A	T	MI.521	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	244	82	T	S	Act/Tct	-6,81	0	0	probably_damaging	0,99	neutral	0,14	neutral	4,49	neutral	1,39	neutral	-2,31	neutral_impact	0,35	neutral	0,87	damaging	0,15	deleterious	1,83	15,18	0,44	0,65	neutral	0,31	neutral	0,24	neutral	0,37	neutral	0,42	2	deleterious	0,99	neutral	0,08	neutral	-2	deleterious	0,67	low_impact	-2,65	medium_impact	-0,15	medium_impact	-0,8	0,63	0,9	15,49	18,3	N	0,36	N	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7603	7603	A	C	MI.5210	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	18	6	Q	H	caA/caC	6,98	1	0	probably_damaging	1	neutral	0,55	neutral	1,39	deleterious	-3,23	deleterious	-4,71	medium_impact	2,77	damaging	0,35	damaging	0,2	deleterious	3,41	23	0,64	0,7	NA	NA	neutral	0,3	disease	0,64	neutral	0,38	2	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,72	low_impact	-3,52	medium_impact	0,25	medium_impact	1,49	0,75	0,85	68,28	15,91	P	0,72	P	0,75	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7603	7603	A	T	MI.5211	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	18	6	Q	H	caA/caT	6,98	1	0	probably_damaging	1	neutral	0,55	neutral	1,39	deleterious	-3,23	deleterious	-4,71	medium_impact	2,77	damaging	0,35	damaging	0,2	deleterious	3,56	23,1	0,64	0,7	NA	NA	neutral	0,3	disease	0,64	neutral	0,38	2	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,72	low_impact	-3,52	medium_impact	0,25	medium_impact	1,49	0,75	0,85	68,28	15,91	P	0,73	P	0,75	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7604	7604	G	C	MI.5212	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	19	7	V	L	Gta/Cta	3,29	0,99	0	benign	0	neutral	1	neutral	1,77	neutral	1,26	neutral	2,41	neutral_impact	-2,23	neutral	0,82	neutral	0,98	neutral	-1,09	0,01	0,47	0,55	NA	NA	neutral	0,06	neutral	0,19	neutral	0,22	6	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,08	high_impact	1,86	low_impact	-3,2	0,42	0,8	61,67	18,86	N	0,42	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7604	7604	G	A	MI.5213	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	19	7	V	M	Gta/Ata	3,29	0,99	0	benign	0	neutral	0,11	neutral	1,62	neutral	-1,04	neutral	0,82	neutral_impact	-0,38	neutral	0,82	neutral	0,9	deleterious	0,76	9,22	0,49	0,55	NA	NA	neutral	0,15	neutral	0,21	neutral	0,24	5	neutral	0,89	deleterious	0,56	neutral	-6	neutral	0,13	high_impact	2,08	medium_impact	-0,3	low_impact	-1,46	0,73	0,85	61,67	18,86	P	0,54	P	0,49	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7604	7604	G	T	MI.5214	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	19	7	V	L	Gta/Tta	3,29	0,99	0	benign	0	neutral	1	neutral	1,77	neutral	1,26	neutral	2,41	neutral_impact	-2,23	neutral	0,82	neutral	0,98	neutral	-0,98	0,02	0,47	0,55	NA	NA	neutral	0,06	neutral	0,19	neutral	0,22	6	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,08	high_impact	1,86	low_impact	-3,2	0,42	0,8	61,67	18,86	N	0,42	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7605	7605	T	G	MI.5215	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	20	7	V	G	gTa/gGa	-0,86	0,02	0	benign	0,14	neutral	0,13	neutral	1,49	neutral	-2,92	deleterious	-4,59	low_impact	1,82	neutral	0,64	neutral	0,54	deleterious	2,13	17,05	0,26	0,45	NA	NA	neutral	0,39	disease	0,57	neutral	0,35	3	neutral	0,85	deleterious	0,5	neutral	-6	neutral	0,29	medium_impact	0,01	medium_impact	-0,25	medium_impact	0,6	0,38	0,8	61,67	18,86	N	0,44	N	0,88	polymorphism	0,58	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7605	7605	T	A	MI.5216	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	20	7	V	E	gTa/gAa	-0,86	0,02	0	benign	0,14	neutral	0,11	neutral	1,49	neutral	-2,7	deleterious	-3,68	low_impact	1,82	neutral	0,63	neutral	0,53	deleterious	3,22	22,7	0,29	0,45	NA	NA	disease	0,58	disease	0,7	disease	0,72	4	neutral	0,87	deleterious	0,49	neutral	-6	neutral	0,36	medium_impact	0,01	medium_impact	-0,3	medium_impact	0,6	0,35	0,8	61,67	18,86	N	0,38	N	0,85	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7605	7605	T	C	MI.5217	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	20	7	V	A	gTa/gCa	-0,86	0,02	0	benign	0,05	neutral	0,2	neutral	1,55	neutral	-1,14	neutral	-1,87	low_impact	1,12	neutral	0,67	neutral	0,71	neutral	1,76	14,76	0,43	0,55	NA	NA	neutral	0,17	disease	0,57	neutral	0,28	4	neutral	0,79	deleterious	0,58	neutral	-6	neutral	0,16	medium_impact	0,47	medium_impact	-0,13	medium_impact	-0,06	0,29	0,8	61,67	18,86	N	0,48	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7607	7607	G	C	MI.5218	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	22	8	G	R	Ggt/Cgt	0,52	0,98	0	probably_damaging	0,92	neutral	0,37	neutral	1,53	neutral	-1,06	deleterious	-7,15	medium_impact	3,08	damaging	0,37	damaging	0,15	deleterious	3,64	23,2	0,32	0,5	NA	NA	disease	0,8	disease	0,73	disease	0,77	5	neutral	0,92	neutral	0,23	deleterious	1	deleterious	0,81	low_impact	-1,71	medium_impact	0,08	medium_impact	1,78	0,74	0,85	66,96	15,06	P	0,64	P	0,99	polymorphism	0,84	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7607	7607	G	T	MI.5219	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	22	8	G	C	Ggt/Tgt	0,52	0,98	0	probably_damaging	0,95	neutral	0,16	neutral	1,49	neutral	-2,99	deleterious	-8,22	high_impact	3,78	damaging	0,41	damaging	0,18	deleterious	3,82	23,4	0,28	0,45	NA	NA	disease	0,79	disease	0,67	disease	0,74	5	neutral	0,97	neutral	0,11	deleterious	2	deleterious	0,77	low_impact	-1,91	medium_impact	-0,19	high_impact	2,44	0,53	0,8	66,96	15,06	P	0,6	P	0,88	polymorphism	0,73	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8770	8770	A	G	MI.522	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	244	82	T	A	Act/Gct	-6,81	0	0	probably_damaging	0,99	neutral	0,23	neutral	4,48	neutral	1,42	deleterious	-2,67	neutral_impact	0,22	neutral	0,86	damaging	0,12	deleterious	2,06	16,6	0,55	0,65	neutral	0,26	neutral	0,24	neutral	0,49	neutral	0,43	1	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,67	low_impact	-2,65	medium_impact	-0,01	medium_impact	-0,91	0,54	0,9	15,49	18,3	N	0,3	N	0,63	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7607	7607	G	A	MI.5220	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	22	8	G	S	Ggt/Agt	0,52	0,98	0	benign	0,06	neutral	0,67	neutral	1,56	neutral	-0,36	deleterious	-5,25	low_impact	1,37	damaging	0,55	neutral	0,43	neutral	0,93	10,28	0,46	0,55	NA	NA	neutral	0,38	neutral	0,36	neutral	0,17	7	neutral	0,25	deleterious	0,81	neutral	-6	neutral	0,16	medium_impact	0,39	medium_impact	0,38	medium_impact	0,18	0,6	0,8	66,96	15,06	N	0,44	N	0,38	polymorphism	0,92	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7608	7608	G	A	MI.5221	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	23	8	G	D	gGt/gAt	6,06	1	0	possibly_damaging	0,69	neutral	0,19	neutral	1,52	neutral	-1,35	deleterious	-6,16	medium_impact	2,5	damaging	0,38	damaging	0,17	deleterious	3,44	23	0,29	0,45	NA	NA	disease	0,8	disease	0,71	disease	0,76	5	neutral	0,84	neutral	0,25	NA	0	deleterious	0,72	low_impact	-1,04	medium_impact	-0,14	medium_impact	1,24	0,33	0,8	66,96	15,06	P	0,69	P	0,9	disease_causing	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7608	7608	G	T	MI.5222	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	23	8	G	V	gGt/gTt	6,06	1	0	possibly_damaging	0,89	neutral	0,5	neutral	1,56	neutral	-0,45	deleterious	-8,2	medium_impact	3,44	damaging	0,4	damaging	0,18	deleterious	3,48	23,1	0,3	0,45	NA	NA	disease	0,73	disease	0,65	disease	0,71	4	neutral	0,88	neutral	0,31	NA	0	deleterious	0,75	low_impact	-1,57	medium_impact	0,21	high_impact	2,12	0,37	0,8	66,96	15,06	P	0,68	P	0,96	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7608	7608	G	C	MI.5223	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	23	8	G	A	gGt/gCt	6,06	1	0	benign	0,19	neutral	0,55	neutral	1,57	neutral	-0,27	deleterious	-5,42	medium_impact	3,08	damaging	0,52	neutral	0,32	neutral	1,11	11,25	0,53	0,6	NA	NA	neutral	0,46	disease	0,55	neutral	0,43	1	neutral	0,34	deleterious	0,68	neutral	-3	neutral	0,43	medium_impact	-0,13	medium_impact	0,25	medium_impact	1,78	0,61	0,8	66,96	15,06	P	0,52	P	0,72	disease_causing	0,94	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7610	7610	C	G	MI.5224	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	25	9	L	V	Cta/Gta	-11,01	0	0	probably_damaging	0,99	neutral	0,22	neutral	0,99	deleterious	-3,37	neutral	-1,58	medium_impact	3,02	damaging	0,49	damaging	0,21	deleterious	3,22	22,7	0,42	0,55	NA	NA	disease	0,61	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,79	low_impact	-2,58	medium_impact	-0,1	medium_impact	1,73	0,43	0,8	25,55	20,86	N	0,34	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7610	7610	C	A	MI.5225	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	25	9	L	M	Cta/Ata	-11,01	0	0	probably_damaging	1	neutral	0,11	neutral	1,07	neutral	-2,41	neutral	-0,62	low_impact	1,66	damaging	0,57	damaging	0,22	deleterious	3,52	23,1	0,32	0,5	NA	NA	neutral	0,49	neutral	0,35	neutral	0,4	2	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,76	low_impact	-3,52	medium_impact	-0,3	medium_impact	0,45	0,68	0,85	25,55	20,86	N	0,41	N	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7611	7611	T	A	MI.5226	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	26	9	L	Q	cTa/cAa	1,21	0,87	0	probably_damaging	1	neutral	0,13	neutral	0,93	deleterious	-6,26	deleterious	-3,8	medium_impact	3,23	damaging	0,56	damaging	0,18	deleterious	3,79	23,4	0,19	0,45	NA	NA	disease	0,79	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,83	low_impact	-3,52	medium_impact	-0,25	medium_impact	1,92	0,52	0,8	25,55	20,86	N	0,35	N	0,85	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7611	7611	T	G	MI.5227	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	26	9	L	R	cTa/cGa	1,21	0,87	0	probably_damaging	1	neutral	0,13	neutral	0,92	deleterious	-6,36	deleterious	-3,81	medium_impact	3,23	damaging	0,44	damaging	0,11	deleterious	3,89	23,5	0,18	0,45	NA	NA	disease	0,89	disease	0,78	disease	0,82	6	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,91	low_impact	-3,52	medium_impact	-0,25	medium_impact	1,92	0,62	0,8	25,55	20,86	N	0,47	N	0,92	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7611	7611	T	C	MI.5228	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	26	9	L	P	cTa/cCa	1,21	0,87	0	probably_damaging	1	neutral	0,11	neutral	0,92	deleterious	-6,82	deleterious	-4,77	medium_impact	3,02	damaging	0,42	damaging	0,1	deleterious	3,65	23,2	0,16	0,45	NA	NA	disease	0,87	disease	0,67	disease	0,75	5	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,89	low_impact	-3,52	medium_impact	-0,3	medium_impact	1,73	0,45	0,8	25,55	20,86	N	0,41	N	0,95	polymorphism	0,95	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7613	7613	C	A	MI.5229	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	28	10	Q	K	Caa/Aaa	-8,47	0	0	probably_damaging	0,99	neutral	0,65	neutral	1,23	neutral	-2,33	deleterious	-3,89	high_impact	3,95	damaging	0,14	damaging	0,04	deleterious	3,75	23,3	0,52	0,6	NA	NA	disease	0,82	disease	0,72	disease	0,74	5	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,85	low_impact	-2,58	medium_impact	0,35	high_impact	2,6	0,56	0,8	68,28	17,96	P	0,65	P	0,97	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8771	8771	C	A	MI.523	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	245	82	T	N	aCt/aAt	0,36	0,01	0	probably_damaging	1	neutral	0,32	neutral	4,35	neutral	1,39	deleterious	-3,12	neutral_impact	0,08	neutral	0,87	damaging	0,25	deleterious	2,41	18,88	0,53	0,65	neutral	0,28	neutral	0,21	neutral	0,35	neutral	0,35	3	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,67	low_impact	-3,6	medium_impact	0,11	low_impact	-1,03	0,8	0,9	15,49	18,3	N	0,34	N	0,9	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7613	7613	C	G	MI.5230	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	28	10	Q	E	Caa/Gaa	-8,47	0	0	probably_damaging	0,98	neutral	0,68	neutral	1,22	neutral	-2,52	deleterious	-2,92	high_impact	3,95	damaging	0,15	damaging	0,05	deleterious	2,93	22	0,5	0,6	NA	NA	disease	0,69	disease	0,72	disease	0,72	4	deleterious	0,98	neutral	0,35	deleterious	2	deleterious	0,83	low_impact	-2,3	medium_impact	0,39	high_impact	2,6	0,61	0,8	68,28	17,96	P	0,64	P	0,85	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7614	7614	A	G	MI.5231	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	29	10	Q	R	cAa/cGa	5,6	1	0	probably_damaging	1	neutral	0,37	neutral	1,2	neutral	-2,93	deleterious	-3,89	high_impact	4,5	damaging	0,15	damaging	0,03	deleterious	3,17	22,7	0,58	0,65	NA	NA	disease	0,82	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	0,08	high_impact	3,11	0,42	0,8	68,28	17,96	P	0,86	P	0,95	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7614	7614	A	C	MI.5232	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	29	10	Q	P	cAa/cCa	5,6	1	0	probably_damaging	1	neutral	0,25	neutral	1,2	neutral	-2,75	deleterious	-5,84	medium_impact	3,4	damaging	0,14	damaging	0,03	deleterious	3,01	22,3	0,23	0,45	NA	NA	disease	0,84	disease	0,67	disease	0,75	5	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,88	low_impact	-3,52	medium_impact	-0,06	high_impact	2,08	0,49	0,8	68,28	17,96	P	0,86	P	0,95	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7614	7614	A	T	MI.5233	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	29	10	Q	L	cAa/cTa	5,6	1	0	probably_damaging	0,99	neutral	0,36	neutral	1,24	neutral	-2,12	deleterious	-6,82	medium_impact	2,93	damaging	0,2	damaging	0,03	deleterious	3,45	23	0,31	0,45	NA	NA	disease	0,78	disease	0,64	disease	0,53	1	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,83	low_impact	-2,58	medium_impact	0,07	medium_impact	1,64	0,3	0,8	68,28	17,96	P	0,84	P	0,97	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7615	7615	A	T	MI.5234	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	30	10	Q	H	caA/caT	6,98	1	0	probably_damaging	1	neutral	0,14	neutral	1,16	deleterious	-4,19	deleterious	-4,87	high_impact	3,95	damaging	0,15	damaging	0,02	deleterious	3,4	23	0,49	0,55	NA	NA	disease	0,72	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	-0,23	high_impact	2,6	0,48	0,8	68,28	17,96	P	0,89	P	0,86	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7615	7615	A	C	MI.5235	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	30	10	Q	H	caA/caC	6,98	1	0	probably_damaging	1	neutral	0,14	neutral	1,16	deleterious	-4,19	deleterious	-4,87	high_impact	3,95	damaging	0,15	damaging	0,02	deleterious	3,23	22,8	0,49	0,55	NA	NA	disease	0,72	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	-0,23	high_impact	2,6	0,48	0,8	68,28	17,96	P	0,88	P	0,86	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7616	7616	G	A	MI.5236	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	31	11	D	N	Gac/Aac	3,98	1	0	probably_damaging	1	neutral	0,42	neutral	1,38	neutral	-1,26	deleterious	-4,13	low_impact	1,73	damaging	0,32	damaging	0,25	deleterious	2,94	22	0,75	0,8	NA	NA	disease	0,56	disease	0,66	neutral	0,45	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,76	low_impact	-3,52	medium_impact	0,13	medium_impact	0,52	0,61	0,8	70,93	13,97	P	0,79	P	0,99	disease_causing	0,96	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7616	7616	G	C	MI.5237	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	31	11	D	H	Gac/Cac	3,98	1	0	probably_damaging	1	neutral	0,08	neutral	1,24	deleterious	-3,69	deleterious	-6,3	high_impact	4,02	damaging	0,5	damaging	0,02	deleterious	3,41	23	0,35	0,5	NA	NA	disease	0,8	disease	0,8	disease	0,78	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,81	low_impact	-3,52	medium_impact	-0,38	high_impact	2,66	0,26	0,8	70,93	13,97	P	0,51	P	0,98	disease_causing	0,99	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7616	7616	G	T	MI.5238	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	31	11	D	Y	Gac/Tac	3,98	1	0	probably_damaging	1	neutral	0,07	neutral	1,23	deleterious	-4,29	deleterious	-8,32	medium_impact	3,47	damaging	0,32	damaging	0,02	deleterious	3,68	23,3	0,26	0,45	NA	NA	disease	0,9	disease	0,8	disease	0,82	6	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,85	low_impact	-3,52	medium_impact	-0,42	high_impact	2,15	0,21	0,8	70,93	13,97	P	0,64	P	0,99	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7617	7617	A	T	MI.5239	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	32	11	D	V	gAc/gTc	9,29	1	0	probably_damaging	1	neutral	0,26	neutral	1,23	deleterious	-4,11	deleterious	-8,4	high_impact	4,02	damaging	0,38	damaging	0,02	deleterious	3,47	23	0,31	0,45	NA	NA	disease	0,87	disease	0,79	disease	0,81	6	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	-0,05	high_impact	2,66	0,25	0,8	70,93	13,97	P	0,65	P	0,99	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8771	8771	C	T	MI.524	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	245	82	T	I	aCt/aTt	0,36	0,01	0	probably_damaging	1	neutral	0,92	neutral	4,41	neutral	0,09	neutral	-2,02	neutral_impact	-0,54	neutral	0,75	neutral	0,37	deleterious	1,86	15,34	0,48	0,65	neutral	0,42	neutral	0,25	neutral	0,38	neutral	0,43	1	deleterious	0,99	neutral	0,46	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,89	low_impact	-1,56	0,69	0,9	15,49	18,3	N	0,21	N	0,97	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7617	7617	A	G	MI.5240	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	32	11	D	G	gAc/gGc	9,29	1	0	probably_damaging	1	neutral	0,27	neutral	1,29	neutral	-2,28	deleterious	-6,38	high_impact	3,67	damaging	0,41	damaging	0,03	deleterious	3,74	23,3	0,3	0,45	NA	NA	disease	0,82	disease	0,76	disease	0,76	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,81	low_impact	-3,52	medium_impact	-0,03	high_impact	2,34	0,26	0,8	70,93	13,97	P	0,68	P	0,97	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7617	7617	A	C	MI.5241	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	32	11	D	A	gAc/gCc	9,29	1	0	probably_damaging	1	neutral	0,45	neutral	1,28	neutral	-2,6	deleterious	-7,42	medium_impact	3,4	neutral	0,75	damaging	0,09	deleterious	3,38	23	0,29	0,45	NA	NA	disease	0,75	disease	0,76	disease	0,74	5	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-3,52	medium_impact	0,16	high_impact	2,08	0,28	0,8	70,93	13,97	N	0,55	P	0,96	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7618	7618	C	A	MI.5242	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	33	11	D	E	gaC/gaA	8,59	1	0	probably_damaging	1	neutral	0,61	neutral	1,35	neutral	-1,47	deleterious	-3,67	medium_impact	2,52	damaging	0,27	damaging	0,03	deleterious	4	23,6	0,58	0,65	NA	NA	disease	0,7	disease	0,67	disease	0,54	1	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,79	low_impact	-3,52	medium_impact	0,31	medium_impact	1,26	0,42	0,8	70,93	13,97	P	0,85	P	0,95	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7618	7618	C	G	MI.5243	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	33	11	D	E	gaC/gaG	8,59	1	0	probably_damaging	1	neutral	0,61	neutral	1,35	neutral	-1,47	deleterious	-3,67	medium_impact	2,52	damaging	0,27	damaging	0,03	deleterious	3,66	23,2	0,58	0,65	NA	NA	disease	0,7	disease	0,67	disease	0,54	1	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,79	low_impact	-3,52	medium_impact	0,31	medium_impact	1,26	0,42	0,8	70,93	13,97	P	0,85	P	0,95	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7619	7619	G	A	MI.5244	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	34	12	A	T	Gct/Act	-5,01	0	0	benign	0,03	neutral	0,26	neutral	1,16	deleterious	-3,14	deleterious	-3,9	medium_impact	3,12	damaging	0,5	neutral	0,3	deleterious	2,14	17,14	0,57	0,65	NA	NA	disease	0,72	disease	0,65	disease	0,7	4	neutral	0,73	deleterious	0,62	neutral	-3	neutral	0,24	medium_impact	0,69	medium_impact	-0,05	medium_impact	1,82	0,65	0,8	68,28	17,75	N	0,37	N	0,72	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7619	7619	G	T	MI.5245	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	34	12	A	S	Gct/Tct	-5,01	0	0	possibly_damaging	0,47	neutral	0,74	neutral	1,62	neutral	0,13	deleterious	-2,92	low_impact	1,2	damaging	0,52	neutral	0,36	deleterious	1,92	15,74	0,51	0,6	NA	NA	neutral	0,14	neutral	0,27	neutral	0,23	5	neutral	0,36	deleterious	0,64	neutral	-3	neutral	0,36	medium_impact	-0,67	medium_impact	0,46	medium_impact	0,02	0,67	0,85	68,28	17,75	N	0,32	N	0,71	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7619	7619	G	C	MI.5246	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	34	12	A	P	Gct/Cct	-5,01	0	0	possibly_damaging	0,82	neutral	0,27	neutral	1,14	deleterious	-3,41	deleterious	-4,87	low_impact	1,86	damaging	0,36	neutral	0,3	deleterious	3,53	23,1	0,19	0,45	NA	NA	disease	0,89	neutral	0,49	disease	0,67	3	neutral	0,87	neutral	0,23	neutral	-3	deleterious	0,83	low_impact	-1,33	medium_impact	-0,03	medium_impact	0,64	0,73	0,85	68,28	17,75	N	0,47	N	0,9	polymorphism	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7620	7620	C	T	MI.5247	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	35	12	A	V	gCt/gTt	5,13	1	0	benign	0,35	neutral	0,2	neutral	1,13	deleterious	-4,02	deleterious	-3,9	medium_impact	3,47	damaging	0,45	neutral	0,28	deleterious	2,51	19,54	0,37	0,5	NA	NA	disease	0,78	disease	0,63	disease	0,73	5	neutral	0,76	neutral	0,43	neutral	-3	deleterious	0,63	medium_impact	-0,47	medium_impact	-0,13	high_impact	2,15	0,67	0,85	68,28	17,75	P	0,56	P	0,79	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7620	7620	C	A	MI.5248	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	35	12	A	D	gCt/gAt	5,13	1	0	possibly_damaging	0,78	neutral	0,15	neutral	1,12	deleterious	-4,45	deleterious	-5,85	high_impact	3,67	damaging	0,38	neutral	0,31	deleterious	4,11	23,7	0,25	0,45	NA	NA	disease	0,9	disease	0,69	disease	0,78	6	neutral	0,9	neutral	0,19	deleterious	1	deleterious	0,8	low_impact	-1,23	medium_impact	-0,21	high_impact	2,34	0,41	0,8	68,28	17,75	P	0,72	P	0,94	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7620	7620	C	G	MI.5249	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	35	12	A	G	gCt/gGt	5,13	1	0	benign	0,24	neutral	0,3	neutral	1,22	neutral	-2,09	deleterious	-3,9	medium_impact	2,16	damaging	0,43	neutral	0,44	deleterious	2	16,23	0,43	0,55	NA	NA	disease	0,66	neutral	0,36	neutral	0,48	0	neutral	0,64	deleterious	0,53	neutral	-3	deleterious	0,44	medium_impact	-0,25	medium_impact	0	medium_impact	0,92	0,71	0,85	68,28	17,75	P	0,66	P	0,74	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8771	8771	C	G	MI.525	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	245	82	T	S	aCt/aGt	0,36	0,01	0	probably_damaging	0,99	neutral	0,14	neutral	4,49	neutral	1,39	neutral	-2,31	neutral_impact	0,35	neutral	0,87	damaging	0,15	deleterious	1,97	16,05	0,44	0,65	neutral	0,31	neutral	0,24	neutral	0,37	neutral	0,42	2	deleterious	0,99	neutral	0,08	neutral	-2	deleterious	0,67	low_impact	-2,65	medium_impact	-0,15	medium_impact	-0,8	0,63	0,9	15,49	18,3	N	0,36	N	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7622	7622	A	T	MI.5250	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	37	13	T	S	Act/Tct	-1,09	0	0	probably_damaging	0,99	neutral	0,76	neutral	1,78	neutral	1,63	neutral	-0,41	neutral_impact	-0,38	neutral	0,72	neutral	0,62	deleterious	0,07	3,26	0,49	0,55	NA	NA	neutral	0,23	neutral	0,21	neutral	0,17	7	deleterious	0,99	neutral	0,39	neutral	-2	deleterious	0,71	low_impact	-2,58	medium_impact	0,48	low_impact	-1,46	0,44	0,8	70,04	13,93	N	0,32	N	0,32	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7622	7622	A	G	MI.5251	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	37	13	T	A	Act/Gct	-1,09	0	0	probably_damaging	0,99	neutral	1	neutral	2,06	neutral	2,77	neutral	0,72	neutral_impact	-1,58	neutral	0,77	neutral	0,71	neutral	-1,38	0	0,48	0,55	NA	NA	neutral	0,06	neutral	0,23	neutral	0,19	6	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,65	low_impact	-2,58	high_impact	1,86	low_impact	-2,59	0,33	0,8	70,04	13,93	N	0,27	N	0,87	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7622	7622	A	C	MI.5252	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	37	13	T	P	Act/Cct	-1,09	0	0	probably_damaging	1	neutral	0,22	neutral	1,51	neutral	-2,08	neutral	-2,41	medium_impact	2,06	damaging	0,38	damaging	0,13	deleterious	3,23	22,8	0,18	0,45	NA	NA	disease	0,82	neutral	0,49	disease	0,73	5	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,83	low_impact	-3,52	medium_impact	-0,1	medium_impact	0,83	0,35	0,8	70,04	13,93	N	0,45	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7623	7623	C	A	MI.5253	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	38	13	T	N	aCt/aAt	-0,17	0	0	probably_damaging	1	neutral	0,58	neutral	1,62	neutral	0,46	deleterious	-2,54	neutral_impact	0	damaging	0,54	damaging	0,17	deleterious	3,26	22,8	0,47	0,55	NA	NA	disease	0,54	neutral	0,25	neutral	0,44	1	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,75	low_impact	-3,52	medium_impact	0,28	low_impact	-1,11	0,56	0,8	70,04	13,93	N	0,28	N	0,82	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7623	7623	C	T	MI.5254	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	38	13	T	I	aCt/aTt	-0,17	0	0	probably_damaging	1	neutral	0,32	neutral	1,51	neutral	-2,14	neutral	-1,96	low_impact	1,31	damaging	0,53	damaging	0,2	deleterious	3,64	23,2	0,31	0,45	NA	NA	disease	0,59	neutral	0,29	neutral	0,48	0	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,77	low_impact	-3,52	medium_impact	0,02	medium_impact	0,12	0,49	0,8	70,04	13,93	N	0,46	N	0,84	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	C7623T	LHON	+	-	Reported	1
chrM	7623	7623	C	G	MI.5255	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	38	13	T	S	aCt/aGt	-0,17	0	0	probably_damaging	0,99	neutral	0,76	neutral	1,78	neutral	1,63	neutral	-0,41	neutral_impact	-0,38	neutral	0,72	neutral	0,62	deleterious	0,23	5,04	0,49	0,55	NA	NA	neutral	0,23	neutral	0,21	neutral	0,17	7	deleterious	0,99	neutral	0,39	neutral	-2	deleterious	0,71	low_impact	-2,58	medium_impact	0,48	low_impact	-1,46	0,44	0,8	70,04	13,93	N	0,31	N	0,32	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7625	7625	T	C	MI.5256	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	40	14	S	P	Tcc/Ccc	-3,86	0	0	probably_damaging	1	neutral	0,16	neutral	0,52	deleterious	-6,15	deleterious	-4,88	high_impact	3,92	damaging	0,3	neutral	0,34	deleterious	3,81	23,4	0,24	0,45	NA	NA	disease	0,83	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	-0,19	high_impact	2,57	0,52	0,8	68,28	17,25	P	0,57	P	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7625	7625	T	A	MI.5257	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	40	14	S	T	Tcc/Acc	-3,86	0	0	probably_damaging	0,99	neutral	0,06	neutral	0,72	neutral	-2,74	deleterious	-2,93	low_impact	1,92	damaging	0,32	neutral	0,37	deleterious	3,6	23,2	0,44	0,55	NA	NA	disease	0,66	disease	0,61	disease	0,57	1	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,79	low_impact	-2,58	medium_impact	-0,46	medium_impact	0,7	0,71	0,85	68,28	17,25	P	0,6	P	0,53	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7625	7625	T	G	MI.5258	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	40	14	S	A	Tcc/Gcc	-3,86	0	0	probably_damaging	0,99	neutral	0,15	neutral	0,6	deleterious	-3,88	deleterious	-2,92	medium_impact	3,38	damaging	0,34	neutral	0,42	deleterious	3,53	23,1	0,43	0,55	NA	NA	disease	0,56	disease	0,65	disease	0,55	1	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,79	low_impact	-2,58	medium_impact	-0,21	high_impact	2,06	0,64	0,8	68,28	17,25	P	0,59	P	0,36	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7626	7626	C	G	MI.5259	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	41	14	S	C	tCc/tGc	5,83	1	0	probably_damaging	1	deleterious	0	neutral	0,51	deleterious	-6,77	deleterious	-4,88	high_impact	3,67	damaging	0,31	neutral	0,33	deleterious	3,41	23	0,32	0,5	NA	NA	disease	0,77	disease	0,66	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,52	low_impact	-1,45	high_impact	2,34	0,61	0,8	68,28	17,25	P	0,7	P	0,91	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8773	8773	A	C	MI.526	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	247	83	N	H	Aac/Cac	-9,59	0	0	probably_damaging	1	deleterious	0,01	neutral	2,79	deleterious	-8,45	deleterious	-4,6	high_impact	4,65	neutral	0,61	neutral	0,3	deleterious	2,97	22,1	0,35	0,65	disease	0,99	disease	0,86	disease	0,76	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-3,6	medium_impact	-0,84	high_impact	2,89	0,44	0,9	49,12	8,61	N	0,47	N	0,98	disease_causing	0,53	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7626	7626	C	A	MI.5260	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	41	14	S	Y	tCc/tAc	5,83	1	0	probably_damaging	1	deleterious	0	neutral	0,5	deleterious	-7,54	deleterious	-5,86	high_impact	4,47	damaging	0,29	damaging	0,26	deleterious	3,86	23,5	0,23	0,45	NA	NA	disease	0,84	disease	0,74	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,52	low_impact	-1,45	high_impact	3,09	0,62	0,8	68,28	17,25	P	0,87	P	1	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7626	7626	C	T	MI.5261	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	41	14	S	F	tCc/tTc	5,83	1	0	probably_damaging	1	neutral	0,06	neutral	0,5	deleterious	-7,31	deleterious	-5,86	high_impact	4,47	damaging	0,31	damaging	0,28	deleterious	4,05	23,7	0,22	0,45	NA	NA	disease	0,86	disease	0,74	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,46	high_impact	3,09	0,39	0,8	68,28	17,25	P	0,74	P	0,99	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7628	7628	C	G	MI.5262	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	43	15	P	A	Cct/Gct	-8,24	0	0	probably_damaging	0,98	neutral	0,2	neutral	1,35	neutral	-1,5	deleterious	-7,85	high_impact	3,94	damaging	0,32	neutral	0,43	deleterious	2,87	21,7	0,37	0,5	NA	NA	disease	0,66	disease	0,62	disease	0,66	3	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,79	low_impact	-2,3	medium_impact	-0,13	high_impact	2,59	0,78	0,85	68,72	18,24	P	0,61	P	0,9	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7628	7628	C	A	MI.5263	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	43	15	P	T	Cct/Act	-8,24	0	0	probably_damaging	1	neutral	0,08	neutral	1,27	neutral	-2,6	deleterious	-7,84	high_impact	3,68	damaging	0,31	neutral	0,29	deleterious	3,56	23,1	0,36	0,5	NA	NA	disease	0,81	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	-0,38	high_impact	2,35	0,64	0,8	68,72	18,24	P	0,54	P	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7628	7628	C	T	MI.5264	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	43	15	P	S	Cct/Tct	-8,24	0	0	probably_damaging	1	neutral	0,2	neutral	1,28	neutral	-2,38	deleterious	-7,84	medium_impact	2,79	damaging	0,34	neutral	0,36	deleterious	3,71	23,3	0,51	0,6	NA	NA	disease	0,79	disease	0,55	neutral	0,49	0	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,85	low_impact	-3,52	medium_impact	-0,13	medium_impact	1,51	0,26	0,8	68,72	18,24	N	0,48	N	0,94	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7629	7629	C	G	MI.5265	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	44	15	P	R	cCt/cGt	5,6	1	0	probably_damaging	1	neutral	0,1	neutral	1,24	deleterious	-3,21	deleterious	-8,83	high_impact	4,14	damaging	0,28	neutral	0,33	deleterious	3,4	23	0,31	0,5	NA	NA	disease	0,89	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,32	high_impact	2,78	0,47	0,8	68,72	18,24	P	0,89	P	0,85	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7629	7629	C	T	MI.5266	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	44	15	P	L	cCt/cTt	5,6	1	0	probably_damaging	1	neutral	0,1	neutral	1,33	neutral	-1,67	deleterious	-9,81	high_impact	3,52	damaging	0,29	neutral	0,44	deleterious	4,11	23,7	0,44	0,55	NA	NA	disease	0,84	disease	0,61	disease	0,71	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,32	high_impact	2,2	0,73	0,85	68,72	18,24	P	0,86	P	0,92	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7629	7629	C	A	MI.5267	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	44	15	P	H	cCt/cAt	5,6	1	0	probably_damaging	1	deleterious	0,03	neutral	1,22	deleterious	-4,11	deleterious	-8,83	high_impact	3,79	damaging	0,28	neutral	0,33	deleterious	3,73	23,3	0,31	0,45	NA	NA	disease	0,85	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-3,52	medium_impact	-0,63	high_impact	2,45	0,55	0,8	68,72	18,24	P	0,89	P	0,79	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7631	7631	A	T	MI.5268	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	46	16	I	F	Atc/Ttc	-9,62	0	0	possibly_damaging	0,53	neutral	0,59	neutral	1,45	neutral	-2,3	deleterious	-3,62	medium_impact	2,36	damaging	0,49	neutral	0,3	deleterious	3,38	22,9	0,52	0,6	NA	NA	disease	0,62	disease	0,64	disease	0,71	4	neutral	0,48	deleterious	0,53	NA	0	deleterious	0,58	medium_impact	-0,77	medium_impact	0,29	medium_impact	1,11	0,63	0,8	68,28	13,53	N	0,33	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7631	7631	A	G	MI.5269	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	46	16	I	V	Atc/Gtc	-9,62	0	0	benign	0	neutral	0,73	neutral	1,56	neutral	-0,56	neutral	-0,79	neutral_impact	0,73	neutral	0,9	neutral	0,87	neutral	-0,97	0,02	0,62	0,65	NA	NA	neutral	0,17	neutral	0,32	neutral	0,22	6	neutral	0,26	deleterious	0,87	neutral	-6	neutral	0,1	high_impact	2,08	medium_impact	0,44	medium_impact	-0,42	0,52	0,8	68,28	13,53	N	0,36	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8773	8773	A	G	MI.527	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	247	83	N	D	Aac/Gac	-9,59	0	0	probably_damaging	0,99	deleterious	0,01	neutral	2,81	deleterious	-7,2	deleterious	-4,6	high_impact	4,65	damaging	0,55	neutral	0,36	deleterious	3,78	23,4	0,46	0,65	disease	0,97	disease	0,81	disease	0,8	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,65	medium_impact	-0,84	high_impact	2,89	0,49	0,9	49,12	8,61	N	0,49	N	0,97	polymorphism	0,65	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7631	7631	A	C	MI.5270	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	46	16	I	L	Atc/Ctc	-9,62	0	0	benign	0,07	neutral	1	neutral	1,6	neutral	-0,61	neutral	-1,35	neutral_impact	0,63	neutral	0,72	neutral	0,77	neutral	-0,11	1,64	0,45	0,55	NA	NA	neutral	0,12	neutral	0,2	neutral	0,23	5	neutral	0,07	deleterious	0,97	neutral	-6	neutral	0,1	medium_impact	0,33	high_impact	1,86	medium_impact	-0,52	0,68	0,85	68,28	13,53	N	0,32	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7632	7632	T	A	MI.5271	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	47	16	I	N	aTc/aAc	2,14	0,97	0	probably_damaging	0,94	neutral	0,29	neutral	1,44	neutral	-2,39	deleterious	-6,46	medium_impact	2,23	damaging	0,53	neutral	0,31	deleterious	4,12	23,8	0,44	0,55	NA	NA	disease	0,74	disease	0,67	disease	0,73	5	neutral	0,95	neutral	0,18	deleterious	1	deleterious	0,77	low_impact	-1,83	medium_impact	-0,01	medium_impact	0,99	0,42	0,8	68,28	13,53	N	0,38	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7632	7632	T	G	MI.5272	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	47	16	I	S	aTc/aGc	2,14	0,97	0	possibly_damaging	0,78	neutral	0,35	neutral	1,45	neutral	-1,69	deleterious	-5,48	medium_impact	2,06	damaging	0,55	neutral	0,38	deleterious	3,88	23,5	0,39	0,5	NA	NA	disease	0,7	disease	0,57	disease	0,67	3	neutral	0,8	neutral	0,29	NA	0	deleterious	0,64	low_impact	-1,23	medium_impact	0,06	medium_impact	0,83	0,41	0,8	68,28	13,53	N	0,41	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7632	7632	T	C	MI.5273	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	47	16	I	T	aTc/aCc	2,14	0,97	0	possibly_damaging	0,51	neutral	0,49	neutral	1,48	neutral	-1,41	deleterious	-4,41	low_impact	1,76	neutral	0,66	neutral	0,37	neutral	1,57	13,7	0,55	0,6	NA	NA	neutral	0,48	neutral	0,44	neutral	0,33	3	neutral	0,52	deleterious	0,49	neutral	-3	deleterious	0,46	medium_impact	-0,74	medium_impact	0,2	medium_impact	0,55	0,46	0,8	68,28	13,53	N	0,42	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7633	7633	C	G	MI.5274	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	48	16	I	M	atC/atG	5,83	0,99	0	possibly_damaging	0,78	neutral	0,3	neutral	1,45	neutral	-1,94	neutral	-2,39	low_impact	1,39	neutral	0,65	neutral	0,4	deleterious	1,86	15,35	0,64	0,7	NA	NA	neutral	0,35	neutral	0,32	neutral	0,17	7	neutral	0,82	neutral	0,26	neutral	-3	deleterious	0,53	low_impact	-1,23	medium_impact	0	medium_impact	0,2	0,68	0,85	68,28	13,53	P	0,56	P	0,79	polymorphism	1	0,05	rs386829011	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7633	7633	C	A	MI.5275	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	48	16	I	M	atC/atA	5,83	0,99	0	possibly_damaging	0,78	neutral	0,3	neutral	1,45	neutral	-1,94	neutral	-2,39	low_impact	1,39	neutral	0,65	neutral	0,4	deleterious	2,39	18,75	0,64	0,7	NA	NA	neutral	0,35	neutral	0,32	neutral	0,17	7	neutral	0,82	neutral	0,26	neutral	-3	deleterious	0,53	low_impact	-1,23	medium_impact	0	medium_impact	0,2	0,68	0,85	68,28	13,53	P	0,56	P	0,79	polymorphism	1	0,05	rs386829011	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7634	7634	A	C	MI.5276	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	49	17	M	L	Ata/Cta	-3,4	0	0	probably_damaging	0,95	neutral	0,28	neutral	1,42	neutral	-1,31	deleterious	-2,93	high_impact	3,53	damaging	0,3	neutral	0,38	deleterious	3,15	22,6	0,46	0,55	NA	NA	disease	0,74	disease	0,64	disease	0,67	3	neutral	0,96	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-1,91	medium_impact	-0,02	high_impact	2,2	0,58	0,8	68,28	18,34	P	0,62	P	0,7	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7634	7634	A	G	MI.5277	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	49	17	M	V	Ata/Gta	-3,4	0	0	probably_damaging	0,97	neutral	0,18	neutral	1,39	neutral	-1,83	deleterious	-3,91	high_impact	3,96	damaging	0,3	damaging	0,26	deleterious	2,65	20,5	0,43	0,55	NA	NA	disease	0,78	disease	0,71	disease	0,73	5	neutral	0,98	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-2,13	medium_impact	-0,16	high_impact	2,61	0,5	0,8	68,28	18,34	P	0,65	P	0,89	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7634	7634	A	T	MI.5278	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	49	17	M	L	Ata/Tta	-3,4	0	0	probably_damaging	0,95	neutral	0,28	neutral	1,42	neutral	-1,31	deleterious	-2,93	high_impact	3,53	damaging	0,3	neutral	0,38	deleterious	3,22	22,7	0,46	0,55	NA	NA	disease	0,74	disease	0,64	disease	0,67	3	neutral	0,96	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-1,91	medium_impact	-0,02	high_impact	2,2	0,58	0,8	68,28	18,34	P	0,63	P	0,7	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7635	7635	T	C	MI.5279	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	50	17	M	T	aTa/aCa	6,98	1	0	probably_damaging	1	neutral	0,21	neutral	1,37	neutral	-2,22	deleterious	-5,85	high_impact	3,96	damaging	0,31	neutral	0,31	deleterious	2,79	21,3	0,33	0,5	NA	NA	disease	0,84	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,11	high_impact	2,61	0,32	0,8	68,28	18,34	P	0,75	P	0,92	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8773	8773	A	T	MI.528	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	247	83	N	Y	Aac/Tac	-9,59	0	0	probably_damaging	1	deleterious	0	neutral	2,79	deleterious	-8,43	deleterious	-7,37	high_impact	4,65	damaging	0,49	neutral	0,29	deleterious	3,63	23,2	0,25	0,65	disease	0,99	disease	0,9	disease	0,75	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,89	0,39	0,9	49,12	8,61	N	0,43	N	1	disease_causing	0,82	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7635	7635	T	A	MI.5280	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	50	17	M	K	aTa/aAa	6,98	1	0	probably_damaging	1	neutral	0,29	neutral	1,35	neutral	-2,7	deleterious	-5,87	medium_impact	3,31	damaging	0,32	damaging	0,26	deleterious	3,82	23,4	0,19	0,45	NA	NA	disease	0,86	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,9	low_impact	-3,52	medium_impact	-0,01	medium_impact	2	0,32	0,8	68,28	18,34	P	0,77	P	1	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7636	7636	A	C	MI.5281	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	51	17	M	I	atA/atC	7,44	1	0	probably_damaging	0,98	neutral	0,17	neutral	1,38	neutral	-2,02	deleterious	-3,91	high_impact	3,81	damaging	0,3	neutral	0,4	deleterious	3,24	22,8	0,45	0,55	NA	NA	disease	0,8	disease	0,7	disease	0,73	5	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-2,3	medium_impact	-0,18	high_impact	2,47	0,74	0,85	68,28	18,34	P	0,81	P	0,78	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7636	7636	A	T	MI.5282	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	51	17	M	I	atA/atT	7,44	1	0	probably_damaging	0,98	neutral	0,17	neutral	1,38	neutral	-2,02	deleterious	-3,91	high_impact	3,81	damaging	0,3	neutral	0,4	deleterious	3,32	22,9	0,45	0,55	NA	NA	disease	0,8	disease	0,7	disease	0,73	5	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-2,3	medium_impact	-0,18	high_impact	2,47	0,74	0,85	68,28	18,34	P	0,83	P	0,78	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7637	7637	G	C	MI.5283	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	52	18	E	Q	Gaa/Caa	1,91	1	0	probably_damaging	0,99	neutral	0,33	neutral	1,27	neutral	-2,21	deleterious	-2,94	medium_impact	2,69	damaging	0,3	neutral	0,33	deleterious	3,1	22,5	0,4	0,5	NA	NA	disease	0,73	neutral	0,49	disease	0,51	0	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,82	low_impact	-2,58	medium_impact	0,04	medium_impact	1,42	0,64	0,8	68,72	18,52	P	0,74	P	0,76	disease_causing	0,96	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7637	7637	G	A	MI.5284	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	52	18	E	K	Gaa/Aaa	1,91	1	0	probably_damaging	0,99	neutral	0,25	neutral	1,29	neutral	-1,93	deleterious	-3,92	high_impact	3,91	damaging	0,29	damaging	0,15	deleterious	4,31	24	0,28	0,45	NA	NA	disease	0,84	disease	0,58	disease	0,7	4	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,88	low_impact	-2,58	medium_impact	-0,06	high_impact	2,56	0,62	0,8	68,72	18,52	P	0,91	P	0,99	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	G7637A	PD risk factor	-	+	Reported	1
chrM	7638	7638	A	C	MI.5285	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	53	18	E	A	gAa/gCa	9,05	1	0	probably_damaging	1	neutral	0,47	neutral	1,26	neutral	-2,37	deleterious	-5,89	high_impact	3,56	damaging	0,34	neutral	0,36	deleterious	3,39	23	0,25	0,45	NA	NA	disease	0,66	disease	0,62	disease	0,66	3	deleterious	0,99	neutral	0,24	deleterious	2	deleterious	0,8	low_impact	-3,52	medium_impact	0,18	high_impact	2,23	0,5	0,8	68,72	18,52	P	0,76	P	0,66	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7638	7638	A	G	MI.5286	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	53	18	E	G	gAa/gGa	9,05	1	0	probably_damaging	1	neutral	0,28	neutral	1,21	deleterious	-3,51	deleterious	-6,86	high_impact	3,56	damaging	0,26	neutral	0,42	deleterious	4,02	23,6	0,31	0,45	NA	NA	disease	0,77	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	-0,02	high_impact	2,23	0,36	0,8	68,72	18,52	P	0,91	P	0,64	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7638	7638	A	T	MI.5287	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	53	18	E	V	gAa/gTa	9,05	1	0	probably_damaging	1	neutral	0,48	neutral	1,2	deleterious	-3,64	deleterious	-6,87	high_impact	3,56	damaging	0,26	damaging	0,26	deleterious	3,9	23,5	0,25	0,45	NA	NA	disease	0,85	disease	0,65	disease	0,73	5	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	0,19	high_impact	2,23	0,44	0,8	68,72	18,52	P	0,9	P	0,82	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7639	7639	A	T	MI.5288	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	54	18	E	D	gaA/gaT	8,59	1	0	probably_damaging	0,97	neutral	0,25	neutral	1,28	neutral	-2,03	deleterious	-2,93	medium_impact	2,56	damaging	0,3	neutral	0,3	deleterious	3,62	23,2	0,38	0,5	NA	NA	disease	0,71	disease	0,55	disease	0,64	3	neutral	0,98	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-2,13	medium_impact	-0,06	medium_impact	1,3	0,48	0,8	68,72	18,52	P	0,81	P	0,81	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7639	7639	A	C	MI.5289	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	54	18	E	D	gaA/gaC	8,59	1	0	probably_damaging	0,97	neutral	0,25	neutral	1,28	neutral	-2,03	deleterious	-2,93	medium_impact	2,56	damaging	0,3	neutral	0,3	deleterious	3,49	23,1	0,38	0,5	NA	NA	disease	0,71	disease	0,55	disease	0,64	3	neutral	0,98	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-2,13	medium_impact	-0,06	medium_impact	1,3	0,48	0,8	68,72	18,52	P	0,81	P	0,81	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8774	8774	A	T	MI.529	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	248	83	N	I	aAc/aTc	8,46	1	0	probably_damaging	1	deleterious	0	neutral	2,8	deleterious	-7,69	deleterious	-8,29	high_impact	4,65	damaging	0,56	neutral	0,47	deleterious	3,82	23,4	0,21	0,65	disease	0,98	disease	0,92	disease	0,71	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,6	low_impact	-1,4	high_impact	2,89	0,39	0,9	49,12	8,61	P	0,52	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7640	7640	G	C	MI.5290	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	55	19	E	Q	Gag/Cag	2,6	1	0	probably_damaging	0,99	neutral	0,66	neutral	1,57	neutral	-0,12	deleterious	-2,95	neutral_impact	0,39	damaging	0,42	damaging	0,03	deleterious	1,85	15,3	0,4	0,5	NA	NA	neutral	0,07	neutral	0,16	neutral	0,23	5	deleterious	0,98	neutral	0,34	neutral	-2	deleterious	0,7	low_impact	-2,58	medium_impact	0,36	medium_impact	-0,74	0,64	0,8	68,72	18,75	P	0,5	N	0,76	disease_causing	0,96	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7640	7640	G	A	MI.5291	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	55	19	E	K	Gag/Aag	2,6	1	0	probably_damaging	0,98	neutral	0,25	neutral	1,57	neutral	-0,14	deleterious	-3,93	medium_impact	2,9	damaging	0,27	damaging	0,03	deleterious	4,32	24	0,28	0,45	NA	NA	disease	0,76	disease	0,57	disease	0,71	4	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,85	low_impact	-2,3	medium_impact	-0,06	medium_impact	1,61	0,56	0,8	68,72	18,75	P	0,84	P	0,99	disease_causing	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7641	7641	A	C	MI.5292	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	56	19	E	A	gAg/gCg	9,29	1	0	probably_damaging	0,99	neutral	0,43	neutral	1,49	neutral	-1,08	deleterious	-5,89	medium_impact	2,79	damaging	0,38	damaging	0,11	deleterious	3,39	23	0,25	0,45	NA	NA	disease	0,52	disease	0,56	disease	0,66	3	deleterious	0,99	neutral	0,22	deleterious	1	deleterious	0,77	low_impact	-2,58	medium_impact	0,14	medium_impact	1,51	0,65	0,8	68,72	18,75	P	0,67	P	0,66	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7641	7641	A	T	MI.5293	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	56	19	E	V	gAg/gTg	9,29	1	0	probably_damaging	0,99	neutral	0,46	neutral	1,43	neutral	-2,38	deleterious	-6,88	medium_impact	3,25	damaging	0,33	damaging	0,03	deleterious	3,95	23,6	0,22	0,45	NA	NA	disease	0,76	disease	0,59	disease	0,71	4	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,83	low_impact	-2,58	medium_impact	0,17	medium_impact	1,94	0,6	0,8	68,72	18,75	P	0,63	P	0,82	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7641	7641	A	G	MI.5294	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	56	19	E	G	gAg/gGg	9,29	1	0	probably_damaging	0,99	neutral	0,4	neutral	1,54	neutral	-0,37	deleterious	-6,88	low_impact	1,56	damaging	0,34	damaging	0,06	deleterious	3,94	23,6	0,32	0,5	NA	NA	disease	0,67	disease	0,59	disease	0,69	4	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,81	low_impact	-2,58	medium_impact	0,11	medium_impact	0,36	0,48	0,8	68,72	18,75	P	0,62	P	0,64	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7642	7642	G	T	MI.5295	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	57	19	E	D	gaG/gaT	8,59	1	0	probably_damaging	0,94	neutral	0,18	neutral	1,49	neutral	-1,06	deleterious	-2,95	medium_impact	2,21	damaging	0,32	damaging	0,05	deleterious	3,57	23,1	0,4	0,5	NA	NA	disease	0,62	neutral	0,39	neutral	0,49	0	neutral	0,96	neutral	0,12	deleterious	1	deleterious	0,79	low_impact	-1,83	medium_impact	-0,16	medium_impact	0,97	0,7	0,85	68,72	18,75	P	0,69	P	0,81	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7642	7642	G	C	MI.5296	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	57	19	E	D	gaG/gaC	8,59	1	0	probably_damaging	0,94	neutral	0,18	neutral	1,49	neutral	-1,06	deleterious	-2,95	medium_impact	2,21	damaging	0,32	damaging	0,05	deleterious	3,41	23	0,4	0,5	NA	NA	disease	0,62	neutral	0,39	neutral	0,49	0	neutral	0,96	neutral	0,12	deleterious	1	deleterious	0,79	low_impact	-1,83	medium_impact	-0,16	medium_impact	0,97	0,7	0,85	68,72	18,75	P	0,69	P	0,81	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7643	7643	C	G	MI.5297	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	58	20	L	V	Ctt/Gtt	0,06	0	0	probably_damaging	0,98	neutral	0,25	neutral	1,32	neutral	-1,26	deleterious	-2,91	medium_impact	3	damaging	0,24	damaging	0,01	deleterious	3,23	22,8	0,35	0,5	NA	NA	disease	0,6	neutral	0,46	neutral	0,47	1	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,79	low_impact	-2,3	medium_impact	-0,06	medium_impact	1,71	0,74	0,85	68,72	18,21	P	0,69	P	0,66	polymorphism	0,53	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7643	7643	C	A	MI.5298	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	58	20	L	I	Ctt/Att	0,06	0	0	probably_damaging	0,99	neutral	0,25	neutral	1,33	neutral	-1,16	neutral	-1,95	low_impact	1,54	damaging	0,31	damaging	0,05	deleterious	4,04	23,7	0,33	0,5	NA	NA	disease	0,64	neutral	0,41	neutral	0,47	1	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,79	low_impact	-2,58	medium_impact	-0,06	medium_impact	0,34	0,71	0,85	68,72	18,21	P	0,53	P	0,63	polymorphism	0,67	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7643	7643	C	T	MI.5299	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	58	20	L	F	Ctt/Ttt	0,06	0	0	probably_damaging	1	neutral	0,29	neutral	1,14	deleterious	-3,52	deleterious	-3,9	medium_impact	3,04	damaging	0,23	damaging	0,04	deleterious	3,77	23,4	0,35	0,5	NA	NA	disease	0,7	disease	0,51	disease	0,53	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,81	low_impact	-3,52	medium_impact	-0,01	medium_impact	1,75	0,74	0,85	68,72	18,21	P	0,71	P	0,91	disease_causing	0,82	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8549	8549	C	T	MI.53	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	23	8	S	L	tCa/tTa	2,9	1	0	benign	0,09	neutral	0,18	neutral	4,65	neutral	-0,84	deleterious	-2,65	low_impact	1,84	neutral	0,84	neutral	0,61	deleterious	3,59	23,2	0,36	0,65	disease	0,68	disease	0,73	neutral	0,48	disease	0,53	1	neutral	0,8	deleterious	0,55	neutral	-6	neutral	0,4	medium_impact	0,2	medium_impact	-0,08	medium_impact	0,48	0,84	0,9	21,24	17,86	P	0,57	P	0,87	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8774	8774	A	C	MI.530	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	248	83	N	T	aAc/aCc	8,46	1	0	probably_damaging	0,99	deleterious	0	neutral	2,82	deleterious	-6,31	deleterious	-5,49	high_impact	4,65	damaging	0,54	neutral	0,4	deleterious	3,27	22,8	0,34	0,65	disease	0,95	disease	0,81	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,65	low_impact	-1,4	high_impact	2,89	0,49	0,9	49,12	8,61	P	0,53	P	0,96	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7644	7644	T	G	MI.5300	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	59	20	L	R	cTt/cGt	-0,4	0	0	probably_damaging	1	neutral	0,09	neutral	1,11	deleterious	-4,85	deleterious	-5,85	high_impact	4,32	damaging	0,2	damaging	0,01	deleterious	4,03	23,7	0,09	0,35	NA	NA	disease	0,89	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	-0,35	high_impact	2,95	0,61	0,8	68,72	18,21	P	0,71	P	0,99	disease_causing	0,97	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7644	7644	T	C	MI.5301	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	59	20	L	P	cTt/cCt	-0,4	0	0	probably_damaging	1	neutral	0,15	neutral	1,1	deleterious	-5,44	deleterious	-6,83	high_impact	3,97	damaging	0,16	damaging	0,04	deleterious	3,67	23,3	0,09	0,35	NA	NA	disease	0,81	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,21	high_impact	2,62	0,54	0,8	68,72	18,21	P	0,72	P	0,99	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7644	7644	T	A	MI.5302	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	59	20	L	H	cTt/cAt	-0,4	0	0	probably_damaging	1	neutral	0,14	neutral	1,1	deleterious	-5,49	deleterious	-6,83	high_impact	4,32	damaging	0,26	damaging	0,01	deleterious	3,93	23,5	0,14	0,4	NA	NA	disease	0,81	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	-0,23	high_impact	2,95	0,64	0,8	68,72	18,21	P	0,61	P	0,94	disease_causing	0,95	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7646	7646	A	G	MI.5303	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	61	21	I	V	Atc/Gtc	-14,47	0	0	benign	0	neutral	0,53	neutral	1,47	neutral	-1	neutral	-0,82	low_impact	1,07	neutral	0,85	neutral	0,86	neutral	-0,23	0,95	0,64	0,7	NA	NA	neutral	0,25	neutral	0,27	neutral	0,21	6	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,1	high_impact	2,08	medium_impact	0,23	medium_impact	-0,1	0,54	0,8	32,6	58,85	N	0,37	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7646	7646	A	C	MI.5304	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	61	21	I	L	Atc/Ctc	-14,47	0	0	benign	0,02	neutral	1	neutral	1,52	neutral	-0,53	neutral	0,86	neutral_impact	0,48	neutral	0,77	neutral	0,96	neutral	-0,99	0,02	0,43	0,55	NA	NA	neutral	0,27	neutral	0,19	neutral	0,2	6	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,12	medium_impact	0,86	high_impact	1,86	medium_impact	-0,66	0,74	0,85	32,6	58,85	N	0,35	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7646	7646	A	T	MI.5305	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	61	21	I	F	Atc/Ttc	-14,47	0	0	benign	0,24	neutral	0,64	neutral	1,42	neutral	-1,84	neutral	-2,3	medium_impact	2,69	damaging	0,54	neutral	0,49	deleterious	1,91	15,62	0,42	0,55	NA	NA	disease	0,62	disease	0,56	disease	0,68	4	neutral	0,25	deleterious	0,7	neutral	-3	neutral	0,38	medium_impact	-0,25	medium_impact	0,34	medium_impact	1,42	0,72	0,85	32,6	58,85	N	0,33	N	0,36	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7647	7647	T	C	MI.5306	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	62	21	I	T	aTc/aCc	-0,86	0	0	benign	0,07	neutral	0,35	neutral	1,44	neutral	-1,55	deleterious	-3,12	low_impact	1,44	neutral	0,73	neutral	0,73	deleterious	0,2	4,73	0,49	0,55	NA	NA	neutral	0,35	neutral	0,31	neutral	0,2	6	neutral	0,61	deleterious	0,64	neutral	-6	neutral	0,16	medium_impact	0,33	medium_impact	0,06	medium_impact	0,25	0,59	0,8	32,6	58,85	N	0,42	N	0,14	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7647	7647	T	G	MI.5307	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	62	21	I	S	aTc/aGc	-0,86	0	0	benign	0,11	neutral	0,51	neutral	1,43	neutral	-1,73	deleterious	-4,06	low_impact	1,14	neutral	0,62	neutral	0,53	deleterious	2,13	17,02	0,36	0,5	NA	NA	disease	0,6	neutral	0,33	neutral	0,46	1	neutral	0,41	deleterious	0,7	neutral	-6	neutral	0,23	medium_impact	0,13	medium_impact	0,21	medium_impact	-0,04	0,56	0,8	32,6	58,85	N	0,33	N	0,22	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7647	7647	T	A	MI.5308	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	62	21	I	N	aTc/aAc	-0,86	0	0	benign	0,41	neutral	0,27	neutral	1,41	neutral	-2,24	deleterious	-5	low_impact	1,73	neutral	0,62	neutral	0,48	deleterious	2,49	19,38	0,31	0,45	NA	NA	disease	0,61	neutral	0,34	neutral	0,46	1	neutral	0,69	neutral	0,43	neutral	-6	deleterious	0,46	medium_impact	-0,57	medium_impact	-0,03	medium_impact	0,52	0,58	0,8	32,6	58,85	N	0,39	N	0,46	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7648	7648	C	A	MI.5309	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	63	21	I	M	atC/atA	3,75	0,41	0	possibly_damaging	0,49	neutral	0,4	neutral	1,41	neutral	-2,14	neutral	-0,38	neutral_impact	0,76	neutral	0,76	neutral	0,95	deleterious	2,02	16,35	0,49	0,55	NA	NA	neutral	0,25	neutral	0,22	neutral	0,21	6	neutral	0,57	neutral	0,46	neutral	-3	neutral	0,36	medium_impact	-0,7	medium_impact	0,11	medium_impact	-0,39	0,8	0,85	32,6	58,85	N	0,4	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8774	8774	A	G	MI.531	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	248	83	N	S	aAc/aGc	8,46	1	0	probably_damaging	0,99	deleterious	0	neutral	2,84	deleterious	-5,83	deleterious	-4,57	high_impact	4,1	damaging	0,48	neutral	0,47	deleterious	3,03	22,3	0,52	0,65	disease	0,93	disease	0,81	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,65	low_impact	-1,4	high_impact	2,42	0,37	0,9	49,12	8,61	P	0,53	P	0,91	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7648	7648	C	G	MI.5310	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	63	21	I	M	atC/atG	3,75	0,41	0	possibly_damaging	0,49	neutral	0,4	neutral	1,41	neutral	-2,14	neutral	-0,38	neutral_impact	0,76	neutral	0,76	neutral	0,95	neutral	1,57	13,71	0,49	0,55	NA	NA	neutral	0,25	neutral	0,22	neutral	0,21	6	neutral	0,57	neutral	0,46	neutral	-3	neutral	0,36	medium_impact	-0,7	medium_impact	0,11	medium_impact	-0,39	0,8	0,85	32,6	58,85	N	0,4	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7649	7649	A	G	MI.5311	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	64	22	T	A	Acc/Gcc	-5,01	0	0	benign	0	neutral	0,5	neutral	1,6	neutral	0	neutral	0	neutral_impact	-0,42	neutral	0,91	neutral	0,88	deleterious	0,21	4,74	0,58	0,65	NA	NA	neutral	0,28	neutral	0,34	neutral	0,15	7	neutral	0,5	deleterious	0,75	neutral	-6	neutral	0,12	high_impact	2,08	medium_impact	0,21	low_impact	-1,5	0,5	0,8	34,36	63,84	N	0,32	N	0,25	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7649	7649	A	C	MI.5312	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	64	22	T	P	Acc/Ccc	-5,01	0	0	benign	0,14	neutral	0,22	neutral	1,54	neutral	-1,81	neutral	-0,42	low_impact	0,9	neutral	0,65	neutral	0,49	neutral	1,55	13,58	0,12	0,4	NA	NA	disease	0,76	disease	0,58	disease	0,69	4	neutral	0,75	deleterious	0,54	neutral	-6	neutral	0,29	medium_impact	0,01	medium_impact	-0,1	medium_impact	-0,26	0,66	0,8	34,36	63,84	N	0,34	N	0,32	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7649	7649	A	T	MI.5313	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	64	22	T	S	Acc/Tcc	-5,01	0	0	benign	0	neutral	0,41	neutral	1,6	neutral	0,35	neutral	0,69	neutral_impact	-0,77	neutral	0,86	neutral	0,95	deleterious	0	2,62	0,43	0,55	NA	NA	neutral	0,3	neutral	0,32	neutral	0,15	7	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,14	high_impact	2,08	medium_impact	0,12	low_impact	-1,83	0,75	0,85	34,36	63,84	N	0,31	N	0,13	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7650	7650	C	A	MI.5314	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	65	22	T	N	aCc/aAc	-0,17	0	0	benign	0,08	neutral	0,3	neutral	1,59	neutral	-0,27	neutral	1,93	neutral_impact	-1	neutral	0,75	neutral	0,96	neutral	1,6	13,88	0,44	0,55	NA	NA	neutral	0,5	neutral	0,21	neutral	0,42	2	neutral	0,67	deleterious	0,61	neutral	-6	neutral	0,18	medium_impact	0,27	medium_impact	0	low_impact	-2,04	0,78	0,85	34,36	63,84	N	0,41	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7650	7650	C	G	MI.5315	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	65	22	T	S	aCc/aGc	-0,17	0	0	benign	0	neutral	0,41	neutral	1,6	neutral	0,35	neutral	0,69	neutral_impact	-0,77	neutral	0,86	neutral	0,95	deleterious	0,23	5,02	0,43	0,55	NA	NA	neutral	0,3	neutral	0,32	neutral	0,15	7	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,14	high_impact	2,08	medium_impact	0,12	low_impact	-1,83	0,75	0,85	34,36	63,84	N	0,31	N	0,13	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7650	7650	C	T	MI.5316	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	65	22	T	I	aCc/aTc	-0,17	0	0	benign	0	neutral	0,44	neutral	1,6	neutral	-1,31	neutral	-0,95	neutral_impact	-0,3	neutral	0,83	neutral	0,83	deleterious	1,87	15,42	0,41	0,5	NA	NA	disease	0,6	neutral	0,44	neutral	0,47	1	neutral	0,56	deleterious	0,72	neutral	-6	neutral	0,17	high_impact	2,08	medium_impact	0,15	low_impact	-1,39	0,7	0,85	34,36	63,84	N	0,31	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7652	7652	T	G	MI.5317	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	67	23	F	V	Ttt/Gtt	-3,4	0	0	probably_damaging	1	neutral	0,12	neutral	1,18	neutral	-2,63	deleterious	-6,06	high_impact	4,17	damaging	0,34	neutral	0,4	deleterious	3,89	23,5	0,22	0,45	NA	NA	disease	0,89	disease	0,76	disease	0,76	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,27	high_impact	2,8	0,68	0,85	68,28	18,81	P	0,69	P	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7652	7652	T	C	MI.5318	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	67	23	F	L	Ttt/Ctt	-3,4	0	0	probably_damaging	1	neutral	0,25	neutral	1,68	neutral	0,29	deleterious	-4,87	medium_impact	2	damaging	0,38	neutral	0,58	deleterious	3,81	23,4	0,37	0,5	NA	NA	disease	0,76	disease	0,52	neutral	0,47	1	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,82	low_impact	-3,52	medium_impact	-0,06	medium_impact	0,77	0,74	0,85	68,28	18,81	P	0,57	P	0,81	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7652	7652	T	A	MI.5319	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	67	23	F	I	Ttt/Att	-3,4	0	0	probably_damaging	1	neutral	0,16	neutral	1,29	neutral	-1,46	deleterious	-5,08	high_impact	4,17	damaging	0,32	neutral	0,51	deleterious	4,22	23,9	0,2	0,45	NA	NA	disease	0,88	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,19	high_impact	2,8	0,67	0,85	68,28	18,81	P	0,74	P	0,87	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8775	8775	C	G	MI.532	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	249	83	N	K	aaC/aaG	6,61	1	0	probably_damaging	0,99	deleterious	0	neutral	2,81	deleterious	-7,02	deleterious	-5,52	high_impact	4,65	damaging	0,46	neutral	0,32	deleterious	3,91	23,5	0,42	0,65	disease	0,98	disease	0,88	disease	0,79	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-2,65	low_impact	-1,4	high_impact	2,89	0,58	0,9	49,12	8,61	P	0,61	P	1	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7653	7653	T	A	MI.5320	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	68	23	F	Y	tTt/tAt	7,44	1	0	probably_damaging	1	neutral	0,12	neutral	1,11	deleterious	-4,58	deleterious	-2,75	medium_impact	3,42	damaging	0,33	neutral	0,36	deleterious	4,03	23,6	0,23	0,45	NA	NA	disease	0,8	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,84	low_impact	-3,52	medium_impact	-0,27	high_impact	2,1	0,68	0,85	68,28	18,81	P	0,78	P	0,76	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7653	7653	T	C	MI.5321	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	68	23	F	S	tTt/tCt	7,44	1	0	probably_damaging	1	neutral	0,07	neutral	1,1	deleterious	-5,21	deleterious	-7,25	high_impact	4,51	damaging	0,34	neutral	0,47	deleterious	4,03	23,6	0,16	0,45	NA	NA	disease	0,85	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	-0,42	high_impact	3,12	0,49	0,8	68,28	18,81	P	0,75	P	0,96	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7653	7653	T	G	MI.5322	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	68	23	F	C	tTt/tGt	7,44	1	0	probably_damaging	1	deleterious	0,01	neutral	1,09	deleterious	-6,04	deleterious	-7,15	high_impact	4,51	damaging	0,32	neutral	0,4	deleterious	3,96	23,6	0,18	0,45	NA	NA	disease	0,84	disease	0,78	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-3,52	medium_impact	-0,9	high_impact	3,12	0,46	0,8	68,28	18,81	P	0,74	P	1	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7654	7654	T	A	MI.5323	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	69	23	F	L	ttT/ttA	7,44	1	0	probably_damaging	1	neutral	0,25	neutral	1,68	neutral	0,29	deleterious	-4,87	medium_impact	2	damaging	0,38	neutral	0,58	deleterious	4,25	23,9	0,37	0,5	NA	NA	disease	0,76	disease	0,52	neutral	0,47	1	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,82	low_impact	-3,52	medium_impact	-0,06	medium_impact	0,77	0,74	0,85	68,28	18,81	P	0,76	P	0,81	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7654	7654	T	G	MI.5324	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	69	23	F	L	ttT/ttG	7,44	1	0	probably_damaging	1	neutral	0,25	neutral	1,68	neutral	0,29	deleterious	-4,87	medium_impact	2	damaging	0,38	neutral	0,58	deleterious	4,17	23,8	0,37	0,5	NA	NA	disease	0,76	disease	0,52	neutral	0,47	1	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,82	low_impact	-3,52	medium_impact	-0,06	medium_impact	0,77	0,74	0,85	68,28	18,81	P	0,76	P	0,81	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7655	7655	C	A	MI.5325	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	70	24	H	N	Cat/Aat	-2,94	0	0	probably_damaging	1	neutral	0,16	neutral	1,2	neutral	-2,86	deleterious	-6,89	medium_impact	2,8	damaging	0,17	damaging	0,01	deleterious	3,74	23,3	0,5	0,6	NA	NA	disease	0,79	disease	0,81	disease	0,73	5	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,84	low_impact	-3,52	medium_impact	-0,19	medium_impact	1,52	0,47	0,8	67,84	19,12	P	0,74	P	0,96	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7655	7655	C	T	MI.5326	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	70	24	H	Y	Cat/Tat	-2,94	0	0	probably_damaging	1	neutral	0,51	neutral	1,22	neutral	-2,39	deleterious	-5,88	medium_impact	2,98	damaging	0,18	damaging	0,01	deleterious	3,41	23	0,46	0,55	NA	NA	disease	0,84	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,87	low_impact	-3,52	medium_impact	0,21	medium_impact	1,69	0,26	0,8	67,84	19,12	P	0,71	P	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7655	7655	C	G	MI.5327	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	70	24	H	D	Cat/Gat	-2,94	0	0	probably_damaging	1	neutral	0,17	neutral	1,2	neutral	-2,74	deleterious	-8,86	medium_impact	3,38	damaging	0,21	damaging	0,02	deleterious	3,68	23,3	0,25	0,45	NA	NA	disease	0,84	disease	0,86	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-3,52	medium_impact	-0,18	high_impact	2,06	0,44	0,8	67,84	19,12	P	0,67	P	0,97	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7656	7656	A	G	MI.5328	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	71	24	H	R	cAt/cGt	7,21	1	0	probably_damaging	1	neutral	0,14	neutral	1,17	deleterious	-3,44	deleterious	-7,87	high_impact	4,53	damaging	0,19	damaging	0,01	deleterious	2,64	20,5	0,45	0,55	NA	NA	disease	0,89	disease	0,84	disease	0,78	6	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,23	high_impact	3,14	0,48	0,8	67,84	19,12	P	0,84	P	0,95	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7656	7656	A	C	MI.5329	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	71	24	H	P	cAt/cCt	7,21	1	0	probably_damaging	1	neutral	0,2	neutral	1,15	deleterious	-4,69	deleterious	-9,84	high_impact	4,18	damaging	0,16	damaging	0,04	deleterious	3,13	22,6	0,26	0,45	NA	NA	disease	0,87	disease	0,87	disease	0,77	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,13	high_impact	2,81	0,28	0,8	67,84	19,12	P	0,82	P	0,98	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8775	8775	C	A	MI.533	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	249	83	N	K	aaC/aaA	6,61	1	0	probably_damaging	0,99	deleterious	0	neutral	2,81	deleterious	-7,02	deleterious	-5,52	high_impact	4,65	damaging	0,46	neutral	0,32	deleterious	4,38	24,1	0,42	0,65	disease	0,98	disease	0,88	disease	0,79	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-2,65	low_impact	-1,4	high_impact	2,89	0,58	0,9	49,12	8,61	P	0,62	P	1	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7656	7656	A	T	MI.5330	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	71	24	H	L	cAt/cTt	7,21	1	0	probably_damaging	1	neutral	0,41	neutral	1,19	deleterious	-3,13	deleterious	-10,81	high_impact	4,53	damaging	0,14	damaging	0,01	neutral	1,69	14,35	0,34	0,5	NA	NA	disease	0,9	disease	0,82	disease	0,77	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,12	high_impact	3,14	0,26	0,8	67,84	19,12	P	0,79	P	0,91	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7657	7657	T	G	MI.5331	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	72	24	H	Q	caT/caG	6,98	1	0	probably_damaging	1	neutral	0,16	neutral	1,18	deleterious	-3,28	deleterious	-7,87	high_impact	3,98	damaging	0,14	damaging	0,02	deleterious	3,3	22,9	0,47	0,55	NA	NA	disease	0,79	disease	0,81	disease	0,73	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	-0,19	high_impact	2,63	0,44	0,8	67,84	19,12	P	0,86	P	0,94	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7657	7657	T	A	MI.5332	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	72	24	H	Q	caT/caA	6,98	1	0	probably_damaging	1	neutral	0,16	neutral	1,18	deleterious	-3,28	deleterious	-7,87	high_impact	3,98	damaging	0,14	damaging	0,02	deleterious	3,55	23,1	0,47	0,55	NA	NA	disease	0,79	disease	0,81	disease	0,73	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	-0,19	high_impact	2,63	0,44	0,8	67,84	19,12	P	0,86	P	0,94	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7658	7658	G	C	MI.5333	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	73	25	D	H	Gat/Cat	-2,48	0	0	probably_damaging	1	neutral	0,35	neutral	1,09	neutral	-2,92	deleterious	-6,9	medium_impact	2,73	damaging	0,12	damaging	0,03	deleterious	3,47	23	0,3	0,45	NA	NA	disease	0,87	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,88	low_impact	-3,52	medium_impact	0,06	medium_impact	1,45	0,26	0,8	67,84	18,97	P	0,71	P	0,98	polymorphism	0,79	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7658	7658	G	A	MI.5334	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	73	25	D	N	Gat/Aat	-2,48	0	0	probably_damaging	1	neutral	0,17	neutral	1,32	neutral	-0,99	deleterious	-4,93	medium_impact	2,32	damaging	0,15	damaging	0,02	deleterious	4,1	23,7	0,62	0,65	NA	NA	disease	0,78	disease	0,62	disease	0,61	2	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,84	low_impact	-3,52	medium_impact	-0,18	medium_impact	1,07	0,46	0,8	67,84	18,97	P	0,79	P	0,99	polymorphism	0,95	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7658	7658	G	T	MI.5335	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	73	25	D	Y	Gat/Tat	-2,48	0	0	probably_damaging	1	neutral	0,56	neutral	1,01	deleterious	-5,94	deleterious	-8,88	high_impact	3,91	damaging	0,16	damaging	0,03	deleterious	3,74	23,3	0,3	0,45	NA	NA	disease	0,93	disease	0,72	disease	0,8	6	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,26	high_impact	2,56	0,25	0,8	67,84	18,97	P	0,54	P	0,99	polymorphism	0,65	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7659	7659	A	C	MI.5336	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	74	25	D	A	gAt/gCt	5,13	1	0	probably_damaging	1	neutral	0,26	neutral	1,05	deleterious	-3,73	deleterious	-7,89	high_impact	3,77	damaging	0,23	damaging	0,1	deleterious	3,57	23,2	0,33	0,5	NA	NA	disease	0,82	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	-0,05	high_impact	2,43	0,24	0,8	67,84	18,97	P	0,83	P	0,96	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7659	7659	A	G	MI.5337	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	74	25	D	G	gAt/gGt	5,13	1	0	probably_damaging	1	neutral	0,19	neutral	1,04	deleterious	-4,16	deleterious	-6,9	medium_impact	3,26	damaging	0,11	damaging	0,03	deleterious	3,93	23,5	0,3	0,45	NA	NA	disease	0,89	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,86	low_impact	-3,52	medium_impact	-0,14	medium_impact	1,95	0,24	0,8	67,84	18,97	P	0,85	P	0,97	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7659	7659	A	T	MI.5338	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	74	25	D	V	gAt/gTt	5,13	1	0	probably_damaging	1	neutral	0,3	neutral	1,02	deleterious	-5,21	deleterious	-8,88	high_impact	4,11	damaging	0,13	damaging	0,01	deleterious	3,64	23,2	0,31	0,45	NA	NA	disease	0,93	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0	high_impact	2,75	0,2	0,8	67,84	18,97	P	0,79	P	0,99	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7660	7660	T	A	MI.5339	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	75	25	D	E	gaT/gaA	8,59	1	0	probably_damaging	0,99	neutral	0,17	neutral	1,13	neutral	-2,43	deleterious	-3,94	medium_impact	3,14	damaging	0,15	damaging	0,03	deleterious	3,92	23,5	0,47	0,55	NA	NA	disease	0,84	disease	0,67	disease	0,72	4	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-2,58	medium_impact	-0,18	medium_impact	1,84	0,44	0,8	67,84	18,97	P	0,91	P	0,95	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8776	8776	C	T	MI.534	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	250	84	L	F	Ctc/Ttc	-4,04	0	0	probably_damaging	1	neutral	0,65	neutral	4,18	neutral	-2,54	deleterious	-3,31	low_impact	1,81	neutral	0,94	neutral	0,65	deleterious	3,85	23,4	0,41	0,65	disease	0,55	neutral	0,35	neutral	0,5	disease	0,58	2	deleterious	0,99	neutral	0,33	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	0,44	medium_impact	0,45	0,5	0,9	42,04	7,65	N	0,28	N	0,97	polymorphism	0,8	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7660	7660	T	G	MI.5340	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	75	25	D	E	gaT/gaG	8,59	1	0	probably_damaging	0,99	neutral	0,17	neutral	1,13	neutral	-2,43	deleterious	-3,94	medium_impact	3,14	damaging	0,15	damaging	0,03	deleterious	3,78	23,4	0,47	0,55	NA	NA	disease	0,84	disease	0,67	disease	0,72	4	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,86	low_impact	-2,58	medium_impact	-0,18	medium_impact	1,84	0,44	0,8	67,84	18,97	P	0,91	P	0,95	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7661	7661	C	A	MI.5341	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	76	26	H	N	Cac/Aac	-2,94	0	0	benign	0,09	neutral	0,14	neutral	1,53	neutral	-0,56	deleterious	-6,89	medium_impact	2,92	damaging	0,31	damaging	0,18	deleterious	1,96	15,95	0,48	0,55	NA	NA	disease	0,82	disease	0,71	disease	0,72	4	neutral	0,85	deleterious	0,53	neutral	-3	neutral	0,33	medium_impact	0,22	medium_impact	-0,23	medium_impact	1,63	0,46	0,8	69,16	14,91	P	0,56	P	0,96	disease_causing	0,68	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7661	7661	C	G	MI.5342	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	76	26	H	D	Cac/Gac	-2,94	0	0	benign	0,14	neutral	0,05	neutral	1,47	neutral	-1,4	deleterious	-8,87	medium_impact	2,64	damaging	0,33	damaging	0,17	deleterious	1,81	15,05	0,24	0,45	NA	NA	disease	0,87	disease	0,79	disease	0,75	5	neutral	0,94	neutral	0,46	neutral	-3	neutral	0,38	medium_impact	0,01	medium_impact	-0,5	medium_impact	1,37	0,46	0,8	69,16	14,91	P	0,58	P	0,97	disease_causing	0,88	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7661	7661	C	T	MI.5343	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	76	26	H	Y	Cac/Tac	-2,94	0	0	benign	0	neutral	0,31	neutral	1,52	neutral	-0,65	deleterious	-5,9	medium_impact	2,16	damaging	0,46	damaging	0,16	neutral	1,48	13,22	0,58	0,65	NA	NA	disease	0,85	disease	0,56	neutral	0,43	1	neutral	0,69	deleterious	0,66	neutral	-3	neutral	0,3	high_impact	2,08	medium_impact	0,01	medium_impact	0,92	0,28	0,8	69,16	14,91	N	0,34	N	0,99	disease_causing	0,73	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7662	7662	A	C	MI.5344	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	77	26	H	P	cAc/cCc	2,83	0,98	0	benign	0,42	neutral	0,09	neutral	1,43	neutral	-2,92	deleterious	-9,85	high_impact	3,76	damaging	0,29	damaging	0,18	deleterious	2,63	20,4	0,24	0,45	NA	NA	disease	0,9	disease	0,81	disease	0,76	5	neutral	0,9	neutral	0,34	neutral	-2	deleterious	0,53	medium_impact	-0,59	medium_impact	-0,35	high_impact	2,42	0,24	0,8	69,16	14,91	P	0,77	P	0,98	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7662	7662	A	T	MI.5345	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	77	26	H	L	cAc/cTc	2,83	0,98	0	benign	0,04	neutral	0,26	neutral	1,47	neutral	-1,43	deleterious	-10,83	medium_impact	2,68	damaging	0,3	neutral	0,3	neutral	1,69	14,33	0,34	0,5	NA	NA	disease	0,92	disease	0,72	disease	0,74	5	neutral	0,72	deleterious	0,61	neutral	-3	neutral	0,33	medium_impact	0,57	medium_impact	-0,05	medium_impact	1,41	0,24	0,8	69,16	14,91	P	0,74	P	0,91	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7662	7662	A	G	MI.5346	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	77	26	H	R	cAc/cGc	2,83	0,98	0	benign	0,06	neutral	0,08	neutral	1,47	neutral	-1,62	deleterious	-7,88	high_impact	3,76	damaging	0,28	damaging	0,15	neutral	0,91	10,14	0,48	0,55	NA	NA	disease	0,91	disease	0,76	disease	0,75	5	neutral	0,91	deleterious	0,51	neutral	-2	neutral	0,37	medium_impact	0,39	medium_impact	-0,38	high_impact	2,42	0,42	0,8	69,16	14,91	P	0,8	P	0,95	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7663	7663	C	A	MI.5347	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	78	26	H	Q	caC/caA	8,59	1	0	benign	0	neutral	0,2	neutral	1,48	neutral	-1,21	deleterious	-7,87	medium_impact	2,9	damaging	0,41	damaging	0,2	neutral	1,75	14,69	0,52	0,6	NA	NA	disease	0,79	disease	0,69	neutral	0,49	0	neutral	0,8	deleterious	0,6	neutral	-3	neutral	0,26	high_impact	2,08	medium_impact	-0,13	medium_impact	1,61	0,42	0,8	69,16	14,91	P	0,65	P	0,94	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7663	7663	C	G	MI.5348	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	78	26	H	Q	caC/caG	8,59	1	0	benign	0	neutral	0,2	neutral	1,48	neutral	-1,21	deleterious	-7,87	medium_impact	2,9	damaging	0,41	damaging	0,2	neutral	1,41	12,83	0,52	0,6	NA	NA	disease	0,79	disease	0,69	neutral	0,49	0	neutral	0,8	deleterious	0,6	neutral	-3	neutral	0,26	high_impact	2,08	medium_impact	-0,13	medium_impact	1,61	0,42	0,8	69,16	14,91	P	0,65	P	0,94	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7664	7664	G	T	MI.5349	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	79	27	A	S	Gcc/Tcc	-2,48	0	0,02	benign	0,34	neutral	0,53	neutral	1,47	neutral	-1,25	neutral	-1,41	low_impact	1,37	damaging	0,54	neutral	0,59	deleterious	0,78	9,36	0,48	0,55	NA	NA	neutral	0,47	neutral	0,38	neutral	0,27	5	neutral	0,39	deleterious	0,6	neutral	-6	neutral	0,34	medium_impact	-0,45	medium_impact	0,23	medium_impact	0,18	0,71	0,85	28,63	44,66	N	0,36	N	0,48	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8776	8776	C	A	MI.535	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	250	84	L	I	Ctc/Atc	-4,04	0	0	probably_damaging	0,99	neutral	0,17	neutral	4,17	neutral	-2,06	neutral	-1,55	low_impact	1,56	neutral	0,94	neutral	0,9	deleterious	3	22,2	0,42	0,65	neutral	0,43	neutral	0,37	neutral	0,41	neutral	0,46	1	deleterious	0,99	neutral	0,09	neutral	-2	deleterious	0,71	low_impact	-2,65	medium_impact	-0,1	medium_impact	0,24	0,65	0,9	42,04	7,65	N	0,45	N	0,87	polymorphism	0,97	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7664	7664	G	C	MI.5350	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	79	27	A	P	Gcc/Ccc	-2,48	0	0,02	possibly_damaging	0,74	neutral	0,3	neutral	1,42	neutral	-2,96	deleterious	-3,37	medium_impact	3,23	damaging	0,42	neutral	0,32	deleterious	3,54	23,1	0,13	0,4	NA	NA	disease	0,89	disease	0,72	disease	0,77	5	neutral	0,79	neutral	0,28	NA	0	deleterious	0,79	low_impact	-1,14	medium_impact	0	medium_impact	1,92	0,71	0,85	28,63	44,66	N	0,44	N	0,69	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7664	7664	G	A	MI.5351	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	79	27	A	T	Gcc/Acc	-2,48	0	0,02	benign	0,02	neutral	0,66	neutral	1,57	neutral	-0,53	neutral	-0,56	neutral_impact	-0,05	neutral	0,79	neutral	0,95	deleterious	0,01	2,69	0,48	0,55	NA	NA	neutral	0,12	neutral	0,28	neutral	0,21	6	neutral	0,3	deleterious	0,82	neutral	-6	neutral	0,12	medium_impact	0,86	medium_impact	0,36	low_impact	-1,15	0,61	0,8	28,63	44,66	N	0,3	N	0,01	polymorphism	1	0,03	rs879139393	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7665	7665	C	A	MI.5352	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	80	27	A	D	gCc/gAc	0,29	0	0	possibly_damaging	0,67	neutral	0,3	neutral	1,42	deleterious	-3,39	deleterious	-3,97	high_impact	3,58	damaging	0,47	neutral	0,33	deleterious	4,17	23,8	0,22	0,45	NA	NA	disease	0,87	disease	0,71	disease	0,77	5	neutral	0,75	neutral	0,32	deleterious	1	deleterious	0,72	low_impact	-1,01	medium_impact	0	high_impact	2,25	0,68	0,85	28,63	44,66	N	0,4	N	0,74	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7665	7665	C	G	MI.5353	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	80	27	A	G	gCc/gGc	0,29	0	0	possibly_damaging	0,54	neutral	0,41	neutral	1,43	neutral	-2,07	deleterious	-3,16	medium_impact	2,68	damaging	0,49	neutral	0,57	deleterious	3,35	22,9	0,28	0,45	NA	NA	disease	0,73	disease	0,57	disease	0,69	4	neutral	0,59	neutral	0,44	NA	0	deleterious	0,5	medium_impact	-0,79	medium_impact	0,12	medium_impact	1,41	0,63	0,8	28,63	44,66	N	0,39	N	0,59	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7665	7665	C	T	MI.5354	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	80	27	A	V	gCc/gTc	0,29	0	0	benign	0,02	neutral	0,65	neutral	1,62	neutral	0,26	neutral	-2,25	low_impact	1,64	neutral	0,63	neutral	0,56	neutral	1,3	12,29	0,31	0,45	NA	NA	disease	0,72	neutral	0,4	neutral	0,49	0	neutral	0,31	deleterious	0,82	neutral	-6	neutral	0,23	medium_impact	0,86	medium_impact	0,35	medium_impact	0,43	0,68	0,85	28,63	44,66	N	0,27	N	0,44	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7667	7667	C	G	MI.5355	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	82	28	L	V	Ctc/Gtc	-11,7	0	0	benign	0,26	neutral	0,23	neutral	1,21	neutral	-2,12	deleterious	-2,62	medium_impact	3,19	damaging	0,33	neutral	0,32	neutral	1,38	12,68	0,41	0,5	NA	NA	disease	0,69	disease	0,57	disease	0,64	3	neutral	0,72	deleterious	0,49	neutral	-3	neutral	0,32	medium_impact	-0,3	medium_impact	-0,09	medium_impact	1,89	0,7	0,85	25,99	26,93	N	0,5	N	0,55	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7667	7667	C	T	MI.5356	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	82	28	L	F	Ctc/Ttc	-11,7	0	0	benign	0,04	neutral	0,37	neutral	1,15	neutral	-2,93	deleterious	-3,46	medium_impact	2,46	damaging	0,51	neutral	0,37	deleterious	1,81	15,03	0,4	0,5	NA	NA	disease	0,74	disease	0,58	disease	0,61	2	neutral	0,6	deleterious	0,67	neutral	-3	neutral	0,26	medium_impact	0,57	medium_impact	0,08	medium_impact	1,2	0,65	0,8	25,99	26,93	N	0,36	N	0,34	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7667	7667	C	A	MI.5357	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	82	28	L	I	Ctc/Atc	-11,7	0	0	possibly_damaging	0,49	neutral	0,24	neutral	1,19	neutral	-2,32	neutral	-1,76	medium_impact	2,52	damaging	0,36	neutral	0,46	deleterious	2,14	17,09	0,41	0,5	NA	NA	disease	0,72	disease	0,55	disease	0,57	1	neutral	0,73	neutral	0,38	NA	0	neutral	0,36	medium_impact	-0,7	medium_impact	-0,07	medium_impact	1,26	0,68	0,85	25,99	26,93	P	0,53	P	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7668	7668	T	C	MI.5358	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	83	28	L	P	cTc/cCc	-1,32	0	0	probably_damaging	0,98	neutral	0,06	neutral	1,09	deleterious	-5,6	deleterious	-6,47	high_impact	4	damaging	0,27	neutral	0,3	deleterious	3,66	23,2	0,16	0,45	NA	NA	disease	0,89	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,89	low_impact	-2,3	medium_impact	-0,46	high_impact	2,65	0,57	0,8	25,99	26,93	P	0,82	P	0,9	polymorphism	0,97	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7668	7668	T	A	MI.5359	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	83	28	L	H	cTc/cAc	-1,32	0	0	probably_damaging	0,97	neutral	0,28	neutral	1,09	deleterious	-5,66	deleterious	-6,41	high_impact	4	damaging	0,39	neutral	0,29	deleterious	3,84	23,4	0,17	0,45	NA	NA	disease	0,84	disease	0,73	disease	0,74	5	neutral	0,98	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-2,13	medium_impact	-0,02	high_impact	2,65	0,65	0,8	25,99	26,93	N	0,46	N	0,84	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8776	8776	C	G	MI.536	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	250	84	L	V	Ctc/Gtc	-4,04	0	0	probably_damaging	0,99	neutral	0,2	neutral	4,23	neutral	-2,07	neutral	-2,32	low_impact	1,79	neutral	0,84	neutral	0,63	deleterious	2,21	17,57	0,45	0,65	disease	0,67	neutral	0,39	neutral	0,45	disease	0,62	2	deleterious	0,99	neutral	0,11	neutral	-2	deleterious	0,74	low_impact	-2,65	medium_impact	-0,05	medium_impact	0,44	0,47	0,9	42,04	7,65	N	0,34	N	0,87	polymorphism	0,95	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7668	7668	T	G	MI.5360	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	83	28	L	R	cTc/cGc	-1,32	0	0	probably_damaging	0,94	neutral	0,17	neutral	1,09	deleterious	-5,05	deleterious	-5,52	high_impact	4	damaging	0,28	damaging	0,26	deleterious	3,72	23,3	0,18	0,45	NA	NA	disease	0,93	disease	0,75	disease	0,82	6	neutral	0,97	neutral	0,12	deleterious	2	deleterious	0,88	low_impact	-1,83	medium_impact	-0,18	high_impact	2,65	0,66	0,8	25,99	26,93	P	0,79	P	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7670	7670	A	T	MI.5361	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	85	29	M	L	Ata/Tta	-0,86	0,01	0	possibly_damaging	0,84	neutral	0,61	neutral	1,57	neutral	0,6	neutral	-2,44	low_impact	1,53	damaging	0,36	damaging	0,05	deleterious	2,06	16,61	0,32	0,5	NA	NA	disease	0,57	neutral	0,41	neutral	0,44	1	neutral	0,81	neutral	0,39	neutral	-3	deleterious	0,59	low_impact	-1,39	medium_impact	0,31	medium_impact	0,33	0,29	0,8	68,72	18,95	N	0,5	N	0,7	polymorphism	1	0,09	rs879117428	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7670	7670	A	G	MI.5362	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	85	29	M	V	Ata/Gta	-0,86	0,01	0	possibly_damaging	0,89	neutral	0,53	neutral	1,53	neutral	0,47	deleterious	-3,25	medium_impact	2,06	damaging	0,18	damaging	0,07	deleterious	2,52	19,62	0,42	0,55	NA	NA	disease	0,8	neutral	0,49	neutral	0,49	0	neutral	0,88	neutral	0,32	NA	0	deleterious	0,75	low_impact	-1,57	medium_impact	0,23	medium_impact	0,83	0,3	0,8	68,72	18,95	P	0,75	P	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7670	7670	A	C	MI.5363	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	85	29	M	L	Ata/Cta	-0,86	0,01	0	possibly_damaging	0,84	neutral	0,61	neutral	1,57	neutral	0,6	neutral	-2,44	low_impact	1,53	damaging	0,36	damaging	0,05	deleterious	1,96	15,95	0,32	0,5	NA	NA	disease	0,57	neutral	0,41	neutral	0,44	1	neutral	0,81	neutral	0,39	neutral	-3	deleterious	0,59	low_impact	-1,39	medium_impact	0,31	medium_impact	0,33	0,29	0,8	68,72	18,95	N	0,49	N	0,7	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7671	7671	T	C	MI.5364	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	86	29	M	T	aTa/aCa	8,59	1	0	probably_damaging	0,98	neutral	0,22	neutral	1,52	neutral	-0,82	deleterious	-5,13	medium_impact	2,37	damaging	0,18	damaging	0,09	deleterious	2,75	21,1	0,3	0,45	NA	NA	disease	0,75	disease	0,51	neutral	0,48	0	deleterious	0,98	neutral	0,12	deleterious	1	deleterious	0,81	low_impact	-2,3	medium_impact	-0,1	medium_impact	1,12	0,3	0,8	68,72	18,95	P	0,85	P	0,92	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7671	7671	T	A	MI.5365	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	86	29	M	K	aTa/aAa	8,59	1	0	probably_damaging	0,95	neutral	0,11	neutral	1,43	neutral	-2,46	deleterious	-5,5	high_impact	3,98	damaging	0,07	damaging	0,01	deleterious	3,79	23,4	0,19	0,45	NA	NA	disease	0,93	disease	0,72	disease	0,8	6	deleterious	0,98	neutral	0,08	deleterious	2	deleterious	0,86	low_impact	-1,91	medium_impact	-0,3	high_impact	2,63	0,38	0,8	68,72	18,95	P	0,9	P	1	disease_causing_automatic	1	0,35	rs199474827	Pathogenic	Cytochrome-c_oxidase_deficiency	RCV000010296.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	T7671A	MM	-	+	Reported	2
chrM	7672	7672	A	T	MI.5366	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	87	29	M	I	atA/atT	4,67	1	0	probably_damaging	0,92	neutral	0,5	neutral	1,53	neutral	0,22	deleterious	-3,23	low_impact	1,54	damaging	0,34	damaging	0,15	deleterious	2,2	17,49	0,37	0,5	NA	NA	disease	0,83	neutral	0,47	neutral	0,49	0	neutral	0,92	neutral	0,29	neutral	-2	deleterious	0,77	low_impact	-1,71	medium_impact	0,21	medium_impact	0,34	0,37	0,8	68,72	18,95	P	0,68	P	0,78	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7672	7672	A	C	MI.5367	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	87	29	M	I	atA/atC	4,67	1	0	probably_damaging	0,92	neutral	0,5	neutral	1,53	neutral	0,22	deleterious	-3,23	low_impact	1,54	damaging	0,34	damaging	0,15	deleterious	2,14	17,13	0,37	0,5	NA	NA	disease	0,83	neutral	0,47	neutral	0,49	0	neutral	0,92	neutral	0,29	neutral	-2	deleterious	0,77	low_impact	-1,71	medium_impact	0,21	medium_impact	0,34	0,37	0,8	68,72	18,95	P	0,67	P	0,78	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7673	7673	A	C	MI.5368	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	88	30	I	L	Atc/Ctc	2,14	1	0,01	benign	0,11	neutral	0,51	neutral	1,36	neutral	-1,28	neutral	-1,67	medium_impact	2,31	damaging	0,57	neutral	0,36	deleterious	1,81	15,06	0,32	0,5	NA	NA	disease	0,7	disease	0,51	neutral	0,48	0	neutral	0,41	deleterious	0,7	neutral	-3	neutral	0,26	medium_impact	0,13	medium_impact	0,21	medium_impact	1,06	0,5	0,8	62,11	14,6	N	0,44	N	0,61	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7673	7673	A	T	MI.5369	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	88	30	I	F	Atc/Ttc	2,14	1	0,01	possibly_damaging	0,69	neutral	0,11	neutral	1,25	neutral	-2,62	deleterious	-3,5	medium_impact	2,15	damaging	0,5	neutral	0,3	deleterious	3,3	22,9	0,31	0,45	NA	NA	disease	0,82	disease	0,58	disease	0,65	3	neutral	0,91	neutral	0,21	NA	0	deleterious	0,7	low_impact	-1,04	medium_impact	-0,3	medium_impact	0,91	0,63	0,8	62,11	14,6	P	0,51	P	0,86	polymorphism	0,9	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8777	8777	T	A	MI.537	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	251	84	L	H	cTc/cAc	0,13	0,01	0	probably_damaging	1	deleterious	0	neutral	4,07	deleterious	-5,48	deleterious	-5,93	high_impact	4,07	neutral	0,79	neutral	0,41	deleterious	4,06	23,7	0,2	0,65	disease	0,93	disease	0,75	disease	0,74	disease	0,8	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,6	low_impact	-1,4	high_impact	2,39	0,57	0,9	42,04	7,65	N	0,34	N	0,97	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7673	7673	A	G	MI.5370	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	88	30	I	V	Atc/Gtc	2,14	1	0,01	benign	0,04	neutral	0,44	neutral	1,36	neutral	-1,31	neutral	-0,19	low_impact	1,19	neutral	0,88	neutral	0,9	neutral	-0,59	0,13	0,42	0,5	NA	NA	neutral	0,29	neutral	0,4	neutral	0,16	7	neutral	0,52	deleterious	0,7	neutral	-6	neutral	0,18	medium_impact	0,57	medium_impact	0,15	medium_impact	0,01	0,37	0,8	62,11	14,6	N	0,5	N	0,42	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7674	7674	T	G	MI.5371	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	89	30	I	S	aTc/aGc	3,52	1	0	benign	0,4	neutral	0,3	neutral	1,24	deleterious	-3,05	deleterious	-4,47	high_impact	3,84	damaging	0,55	neutral	0,35	deleterious	2,5	19,44	0,23	0,45	NA	NA	disease	0,82	disease	0,64	disease	0,66	3	neutral	0,65	neutral	0,45	neutral	-2	deleterious	0,55	medium_impact	-0,56	medium_impact	0	high_impact	2,5	0,54	0,8	62,11	14,6	N	0,47	N	0,86	polymorphism	0,96	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7674	7674	T	C	MI.5372	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	89	30	I	T	aTc/aCc	3,52	1	0	benign	0,03	neutral	0,16	neutral	1,26	neutral	-2,47	deleterious	-3,52	medium_impact	3,21	neutral	0,7	neutral	0,42	neutral	1,35	12,53	0,35	0,5	NA	NA	disease	0,68	disease	0,56	disease	0,54	1	neutral	0,83	deleterious	0,57	neutral	-3	neutral	0,24	medium_impact	0,69	medium_impact	-0,19	medium_impact	1,9	0,6	0,8	62,11	14,6	P	0,54	P	0,93	polymorphism	0,99	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7674	7674	T	A	MI.5373	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	89	30	I	N	aTc/aAc	3,52	1	0	possibly_damaging	0,65	neutral	0,08	neutral	1,21	deleterious	-4,2	deleterious	-5,75	high_impact	3,63	damaging	0,55	neutral	0,28	deleterious	4,1	23,7	0,2	0,45	NA	NA	disease	0,81	disease	0,64	disease	0,66	3	neutral	0,93	neutral	0,22	deleterious	1	deleterious	0,68	medium_impact	-0,97	medium_impact	-0,38	high_impact	2,3	0,6	0,8	62,11	14,6	N	0,47	N	0,99	polymorphism	0,97	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7675	7675	C	A	MI.5374	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	90	30	I	M	atC/atA	4,67	1	0	possibly_damaging	0,83	neutral	0,29	neutral	1,23	deleterious	-3,12	neutral	-2,26	medium_impact	2,83	neutral	0,6	neutral	0,35	deleterious	3,55	23,1	0,33	0,5	NA	NA	disease	0,6	neutral	0,43	neutral	0,38	3	neutral	0,86	neutral	0,23	NA	0	deleterious	0,67	low_impact	-1,36	medium_impact	-0,01	medium_impact	1,55	0,67	0,85	62,11	14,6	P	0,53	P	0,76	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7675	7675	C	G	MI.5375	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	90	30	I	M	atC/atG	4,67	1	0	possibly_damaging	0,83	neutral	0,29	neutral	1,23	deleterious	-3,12	neutral	-2,26	medium_impact	2,83	neutral	0,6	neutral	0,35	deleterious	3,05	22,4	0,33	0,5	NA	NA	disease	0,6	neutral	0,43	neutral	0,38	3	neutral	0,86	neutral	0,23	NA	0	deleterious	0,67	low_impact	-1,36	medium_impact	-0,01	medium_impact	1,55	0,67	0,85	62,11	14,6	P	0,53	P	0,76	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7676	7676	A	C	MI.5376	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	91	31	I	L	Att/Ctt	-7,78	0	0	benign	0,03	neutral	1	neutral	1,99	neutral	1,53	neutral	-1,37	neutral_impact	0,73	neutral	0,71	neutral	0,68	deleterious	-0,06	2,04	0,32	0,5	NA	NA	neutral	0,13	neutral	0,24	neutral	0,2	6	neutral	0,03	deleterious	0,99	neutral	-6	neutral	0,12	medium_impact	0,69	high_impact	1,86	medium_impact	-0,42	0,5	0,8	33,04	38,83	N	0,33	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7676	7676	A	T	MI.5377	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	91	31	I	F	Att/Ttt	-7,78	0	0	benign	0,42	neutral	0,44	neutral	1,36	neutral	-2,84	deleterious	-3,33	medium_impact	3,25	damaging	0,59	neutral	0,5	deleterious	1,92	15,69	0,3	0,45	NA	NA	disease	0,71	disease	0,63	disease	0,71	4	neutral	0,51	deleterious	0,51	neutral	-3	deleterious	0,48	medium_impact	-0,59	medium_impact	0,15	medium_impact	1,94	0,59	0,8	33,04	38,83	N	0,33	N	0,7	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7676	7676	A	G	MI.5378	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	91	31	I	V	Att/Gtt	-7,78	0	0	benign	0,01	neutral	0,61	neutral	1,53	neutral	-0,33	neutral	0,65	neutral_impact	0,52	neutral	0,85	neutral	0,98	neutral	-1,75	0	0,41	0,5	NA	NA	neutral	0,14	neutral	0,35	neutral	0,22	6	neutral	0,38	deleterious	0,8	neutral	-6	neutral	0,13	medium_impact	1,14	medium_impact	0,31	medium_impact	-0,62	0,44	0,8	33,04	38,83	N	0,33	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7677	7677	T	G	MI.5379	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	92	31	I	S	aTt/aGt	4,21	1	0	possibly_damaging	0,45	neutral	0,16	neutral	1,34	deleterious	-3,38	deleterious	-3,96	medium_impact	2,8	neutral	0,62	neutral	0,51	deleterious	3,61	23,2	0,23	0,45	NA	NA	disease	0,67	disease	0,6	disease	0,69	4	neutral	0,82	neutral	0,36	NA	0	deleterious	0,48	medium_impact	-0,64	medium_impact	-0,19	medium_impact	1,52	0,51	0,8	33,04	38,83	N	0,5	N	0,7	polymorphism	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8777	8777	T	G	MI.538	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	251	84	L	R	cTc/cGc	0,13	0,01	0	probably_damaging	1	deleterious	0	neutral	4,08	deleterious	-4,95	deleterious	-5,04	high_impact	4,07	neutral	0,79	neutral	0,38	deleterious	4,12	23,8	0,18	0,65	disease	0,91	disease	0,86	disease	0,77	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,39	0,58	0,9	42,04	7,65	N	0,39	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7677	7677	T	C	MI.5380	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	92	31	I	T	aTt/aCt	4,21	1	0	benign	0,3	neutral	0,35	neutral	1,36	neutral	-2,81	deleterious	-2,58	medium_impact	2,45	neutral	0,76	neutral	0,53	neutral	1,29	12,22	0,28	0,45	NA	NA	neutral	0,44	disease	0,6	neutral	0,4	2	neutral	0,58	deleterious	0,53	neutral	-3	neutral	0,38	medium_impact	-0,38	medium_impact	0,06	medium_impact	1,19	0,62	0,8	33,04	38,83	N	0,53	P	0,55	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7677	7677	T	A	MI.5381	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	92	31	I	N	aTt/aAt	4,21	1	0	possibly_damaging	0,81	neutral	0,07	neutral	1,33	deleterious	-4,49	deleterious	-5,2	medium_impact	2,91	damaging	0,59	neutral	0,48	deleterious	4	23,6	0,18	0,45	NA	NA	disease	0,75	disease	0,62	disease	0,7	4	neutral	0,96	neutral	0,13	NA	0	deleterious	0,69	low_impact	-1,31	medium_impact	-0,42	medium_impact	1,62	0,58	0,8	33,04	38,83	N	0,48	N	0,87	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7678	7678	T	G	MI.5382	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	93	31	I	M	atT/atG	5,83	1	0	benign	0,06	neutral	0,27	neutral	1,36	neutral	-2,61	neutral	-1,46	low_impact	1,25	neutral	0,85	neutral	0,64	neutral	1,26	12,07	0,32	0,5	NA	NA	neutral	0,38	neutral	0,37	neutral	0,15	7	neutral	0,7	deleterious	0,61	neutral	-6	neutral	0,17	medium_impact	0,39	medium_impact	-0,03	medium_impact	0,07	0,63	0,8	33,04	38,83	P	0,58	P	0,03	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7678	7678	T	A	MI.5383	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	93	31	I	M	atT/atA	5,83	1	0	benign	0,06	neutral	0,27	neutral	1,36	neutral	-2,61	neutral	-1,46	low_impact	1,25	neutral	0,85	neutral	0,64	neutral	1,6	13,86	0,32	0,5	NA	NA	neutral	0,38	neutral	0,37	neutral	0,15	7	neutral	0,7	deleterious	0,61	neutral	-6	neutral	0,17	medium_impact	0,39	medium_impact	-0,03	medium_impact	0,07	0,63	0,8	33,04	38,83	P	0,58	P	0,03	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7679	7679	T	G	MI.5384	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	94	32	F	V	Ttc/Gtc	-13,31	0	0	benign	0,02	neutral	0,65	neutral	1,64	neutral	-0,28	deleterious	-4,32	neutral_impact	0,5	neutral	0,63	neutral	0,55	deleterious	0,7	8,81	0,25	0,45	NA	NA	neutral	0,47	neutral	0,38	neutral	0,26	5	neutral	0,31	deleterious	0,82	neutral	-6	neutral	0,15	medium_impact	0,86	medium_impact	0,35	medium_impact	-0,64	0,61	0,8	26,43	36,86	N	0,36	N	0,85	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7679	7679	T	C	MI.5385	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	94	32	F	L	Ttc/Ctc	-13,31	0	0	benign	0,01	neutral	1	neutral	1,67	neutral	-0,66	deleterious	-3,31	neutral_impact	0,21	neutral	0,77	neutral	0,81	deleterious	0,45	7,04	0,38	0,5	NA	NA	neutral	0,4	neutral	0,37	neutral	0,14	7	neutral	0,01	deleterious	1	neutral	-6	neutral	0,13	medium_impact	1,14	high_impact	1,86	medium_impact	-0,91	0,41	0,8	26,43	36,86	N	0,27	N	0,89	polymorphism	1	0,1	rs879003775	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7679	7679	T	A	MI.5386	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	94	32	F	I	Ttc/Atc	-13,31	0	0	benign	0,02	neutral	0,65	neutral	1,69	neutral	-0,29	deleterious	-3,48	neutral_impact	-0,7	neutral	0,7	neutral	0,72	deleterious	0,88	9,95	0,25	0,45	NA	NA	neutral	0,32	neutral	0,32	neutral	0,14	7	neutral	0,31	deleterious	0,82	neutral	-6	neutral	0,14	medium_impact	0,86	medium_impact	0,35	low_impact	-1,76	0,51	0,8	26,43	36,86	N	0,33	N	0,83	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7680	7680	T	G	MI.5387	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	95	32	F	C	tTc/tGc	4,67	1	0	benign	0	neutral	0,05	neutral	1,5	neutral	-2,77	deleterious	-5,75	low_impact	1,72	neutral	0,63	neutral	0,37	deleterious	1,89	15,55	0,2	0,45	NA	NA	disease	0,74	disease	0,54	disease	0,68	4	neutral	0,95	deleterious	0,53	neutral	-6	neutral	0,18	high_impact	2,08	medium_impact	-0,5	medium_impact	0,51	0,35	0,8	26,43	36,86	N	0,48	N	0,94	polymorphism	0,52	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7680	7680	T	C	MI.5388	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	95	32	F	S	tTc/tCc	4,67	1	0	benign	0	neutral	0,07	neutral	1,53	neutral	-2,13	deleterious	-5,91	low_impact	1,29	neutral	0,8	neutral	0,49	deleterious	2,01	16,29	0,28	0,45	NA	NA	disease	0,57	disease	0,51	neutral	0,48	0	neutral	0,93	deleterious	0,54	neutral	-6	neutral	0,18	high_impact	2,08	medium_impact	-0,42	medium_impact	0,1	0,55	0,8	26,43	36,86	N	0,5	N	0,42	polymorphism	0,62	0,12	rs386829012	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7680	7680	T	A	MI.5389	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	95	32	F	Y	tTc/tAc	4,67	1	0	benign	0,06	neutral	0,06	neutral	1,5	neutral	-2,61	neutral	-2,3	low_impact	1,57	neutral	0,72	neutral	0,91	neutral	1,07	11,03	0,27	0,45	NA	NA	disease	0,56	neutral	0,42	neutral	0,45	1	neutral	0,94	deleterious	0,5	neutral	-6	neutral	0,21	medium_impact	0,39	medium_impact	-0,46	medium_impact	0,37	0,56	0,8	26,43	36,86	P	0,56	P	0,74	polymorphism	0,93	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8777	8777	T	C	MI.539	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	251	84	L	P	cTc/cCc	0,13	0,01	0	probably_damaging	1	deleterious	0	neutral	4,09	deleterious	-5,29	deleterious	-5,95	high_impact	3,52	neutral	0,84	neutral	0,41	deleterious	3,83	23,4	0,17	0,65	disease	0,56	disease	0,84	disease	0,77	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,6	low_impact	-1,4	medium_impact	1,92	0,56	0,9	42,04	7,65	N	0,4	N	1	disease_causing	0,99	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7681	7681	C	G	MI.5390	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	96	32	F	L	ttC/ttG	3,75	1	0,01	benign	0,01	neutral	1	neutral	1,67	neutral	-0,66	deleterious	-3,31	neutral_impact	0,21	neutral	0,77	neutral	0,81	deleterious	0,77	9,27	0,38	0,5	NA	NA	neutral	0,4	neutral	0,37	neutral	0,14	7	neutral	0,01	deleterious	1	neutral	-6	neutral	0,13	medium_impact	1,14	high_impact	1,86	medium_impact	-0,91	0,41	0,8	26,43	36,86	N	0,36	N	0,89	disease_causing	0,68	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7681	7681	C	A	MI.5391	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	96	32	F	L	ttC/ttA	3,75	1	0,01	benign	0,01	neutral	1	neutral	1,67	neutral	-0,66	deleterious	-3,31	neutral_impact	0,21	neutral	0,77	neutral	0,81	neutral	1,1	11,21	0,38	0,5	NA	NA	neutral	0,4	neutral	0,37	neutral	0,14	7	neutral	0,01	deleterious	1	neutral	-6	neutral	0,13	medium_impact	1,14	high_impact	1,86	medium_impact	-0,91	0,41	0,8	26,43	36,86	N	0,36	N	0,89	disease_causing	0,68	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7682	7682	C	T	MI.5392	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	97	33	L	F	Ctt/Ttt	-1,78	0	0	possibly_damaging	0,57	neutral	0,64	neutral	1,4	neutral	-1,89	deleterious	-3,57	medium_impact	1,94	damaging	0,52	neutral	0,43	deleterious	2,43	19,01	0,28	0,45	NA	NA	disease	0,73	neutral	0,41	neutral	0,39	2	neutral	0,49	deleterious	0,54	NA	0	deleterious	0,71	medium_impact	-0,84	medium_impact	0,34	medium_impact	0,71	0,57	0,8	66,52	17,02	N	0,31	N	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7682	7682	C	G	MI.5393	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	97	33	L	V	Ctt/Gtt	-1,78	0	0	benign	0,14	neutral	0,26	neutral	1,46	neutral	0,1	neutral	-2,44	medium_impact	2,02	damaging	0,55	neutral	0,39	neutral	1,45	13,04	0,26	0,45	NA	NA	disease	0,62	neutral	0,38	neutral	0,23	5	neutral	0,7	deleterious	0,56	neutral	-3	neutral	0,28	medium_impact	0,01	medium_impact	-0,05	medium_impact	0,79	0,59	0,8	66,52	17,02	N	0,42	N	0,66	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7682	7682	C	A	MI.5394	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	97	33	L	I	Ctt/Att	-1,78	0	0	benign	0,32	neutral	0,45	neutral	1,49	neutral	-0,24	neutral	-1,64	low_impact	1,28	damaging	0,59	neutral	0,53	neutral	1,19	11,67	0,32	0,5	NA	NA	neutral	0,47	neutral	0,33	neutral	0,19	6	neutral	0,46	deleterious	0,57	neutral	-6	neutral	0,29	medium_impact	-0,42	medium_impact	0,16	medium_impact	0,1	0,55	0,8	66,52	17,02	N	0,34	N	0,63	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7683	7683	T	G	MI.5395	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	98	33	L	R	cTt/cGt	-1,32	0	0	possibly_damaging	0,85	neutral	0,16	neutral	1,34	deleterious	-3,41	deleterious	-5,3	high_impact	3,87	damaging	0,44	damaging	0,27	deleterious	3,88	23,5	0,12	0,4	NA	NA	disease	0,93	disease	0,7	disease	0,77	5	neutral	0,92	neutral	0,16	deleterious	1	deleterious	0,85	low_impact	-1,42	medium_impact	-0,19	high_impact	2,52	0,56	0,8	66,52	17,02	N	0,45	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7683	7683	T	C	MI.5396	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	98	33	L	P	cTt/cCt	-1,32	0	0	probably_damaging	0,96	neutral	0,09	neutral	1,33	neutral	-2,99	deleterious	-6,16	medium_impact	2,77	damaging	0,57	damaging	0,27	deleterious	3,63	23,2	0,1	0,4	NA	NA	disease	0,9	disease	0,69	disease	0,76	5	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,88	low_impact	-2,01	medium_impact	-0,35	medium_impact	1,49	0,61	0,8	66,52	17,02	N	0,27	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7683	7683	T	A	MI.5397	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	98	33	L	H	cTt/cAt	-1,32	0	0	probably_damaging	0,94	neutral	0,3	neutral	1,33	deleterious	-3,95	deleterious	-6,24	high_impact	3,87	damaging	0,53	neutral	0,3	deleterious	3,89	23,5	0,13	0,4	NA	NA	disease	0,8	disease	0,66	disease	0,73	5	neutral	0,95	neutral	0,18	deleterious	2	deleterious	0,82	low_impact	-1,83	medium_impact	0	high_impact	2,52	0,57	0,8	66,52	17,02	N	0,35	N	0,94	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7685	7685	A	C	MI.5398	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	100	34	I	L	Atc/Ctc	-2,01	0	0	benign	0,2	neutral	0,24	neutral	0,69	deleterious	-3,24	neutral	-1,98	high_impact	3,79	damaging	0,31	neutral	0,33	deleterious	1,86	15,34	0,31	0,45	NA	NA	disease	0,79	disease	0,67	disease	0,67	3	neutral	0,72	deleterious	0,52	neutral	-2	neutral	0,31	medium_impact	-0,16	medium_impact	-0,07	high_impact	2,45	0,41	0,8	68,72	18,96	P	0,58	P	0,71	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7685	7685	A	G	MI.5399	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	100	34	I	V	Atc/Gtc	-2,01	0	0	benign	0,01	neutral	0,15	neutral	0,9	neutral	-1,88	neutral	-0,91	medium_impact	2,71	damaging	0,34	damaging	0,26	neutral	-0,09	1,79	0,39	0,5	NA	NA	neutral	0,46	disease	0,52	neutral	0,3	4	neutral	0,85	deleterious	0,57	neutral	-3	neutral	0,23	medium_impact	1,14	medium_impact	-0,21	medium_impact	1,44	0,4	0,8	68,72	18,96	P	0,63	P	0,54	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8551	8551	T	C	MI.54	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	25	9	F	L	Ttc/Ctc	0,59	0,99	0	probably_damaging	0,92	neutral	0,06	neutral	3,94	neutral	-0,84	deleterious	-5,27	medium_impact	2,34	damaging	0,57	neutral	0,59	deleterious	3,79	23,4	0,4	0,65	disease	0,6	disease	0,77	disease	0,82	disease	0,8	6	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,76	low_impact	-1,76	medium_impact	-0,38	medium_impact	0,91	0,44	0,9	49,56	8,77	P	0,5	N	0,89	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8779	8779	C	G	MI.540	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	253	85	L	V	Ctc/Gtc	-20	0	0	probably_damaging	0,99	neutral	0,08	neutral	4,17	neutral	-1,48	deleterious	-2,75	medium_impact	2,7	neutral	0,94	damaging	0,17	deleterious	3,36	22,9	0,47	0,65	disease	0,59	disease	0,53	disease	0,61	disease	0,53	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,75	low_impact	-2,65	medium_impact	-0,31	medium_impact	1,22	0,59	0,9	49,56	8,74	N	0,38	N	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7685	7685	A	T	MI.5400	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	100	34	I	F	Atc/Ttc	-2,01	0	0	possibly_damaging	0,84	neutral	0,15	neutral	0,57	deleterious	-5,71	deleterious	-3,95	high_impact	4,04	damaging	0,29	damaging	0,24	deleterious	3,54	23,1	0,3	0,45	NA	NA	disease	0,86	disease	0,72	disease	0,72	4	neutral	0,92	neutral	0,16	deleterious	1	deleterious	0,83	low_impact	-1,39	medium_impact	-0,21	high_impact	2,68	0,62	0,8	68,72	18,96	P	0,75	P	0,92	polymorphism	0,86	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7686	7686	T	G	MI.5401	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	101	34	I	S	aTc/aGc	6,75	1	0	probably_damaging	0,92	neutral	0,1	neutral	0,55	deleterious	-7,45	deleterious	-5,88	high_impact	4,59	damaging	0,29	neutral	0,31	deleterious	4,01	23,6	0,22	0,45	NA	NA	disease	0,86	disease	0,69	disease	0,71	4	neutral	0,97	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-1,71	medium_impact	-0,32	high_impact	3,2	0,42	0,8	68,72	18,96	P	0,87	P	0,91	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7686	7686	T	A	MI.5402	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	101	34	I	N	aTc/aAc	6,75	1	0	probably_damaging	0,98	deleterious	0,03	neutral	0,54	deleterious	-8,51	deleterious	-6,86	high_impact	4,04	damaging	0,31	damaging	0,23	deleterious	4,22	23,9	0,2	0,45	NA	NA	disease	0,86	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,86	low_impact	-2,3	medium_impact	-0,63	high_impact	2,68	0,54	0,8	68,72	18,96	P	0,68	P	0,99	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7686	7686	T	C	MI.5403	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	101	34	I	T	aTc/aCc	6,75	1	0	possibly_damaging	0,78	neutral	0,13	neutral	0,57	deleterious	-5,44	deleterious	-4,86	medium_impact	3,44	damaging	0,34	damaging	0,26	deleterious	3,05	22,4	0,32	0,5	NA	NA	disease	0,73	disease	0,65	disease	0,57	1	neutral	0,91	neutral	0,18	NA	0	deleterious	0,74	low_impact	-1,23	medium_impact	-0,25	high_impact	2,12	0,54	0,8	68,72	18,96	P	0,7	P	0,96	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7687	7687	C	G	MI.5404	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	102	34	I	M	atC/atG	7,44	1	0	probably_damaging	0,92	neutral	0,11	neutral	0,58	deleterious	-5,2	deleterious	-2,92	high_impact	3,56	damaging	0,33	neutral	0,35	deleterious	3,14	22,6	0,31	0,45	NA	NA	disease	0,71	disease	0,66	disease	0,55	1	neutral	0,97	neutral	0,1	deleterious	2	deleterious	0,77	low_impact	-1,71	medium_impact	-0,3	high_impact	2,23	0,64	0,8	68,72	18,96	P	0,73	P	0,79	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7687	7687	C	A	MI.5405	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	102	34	I	M	atC/atA	7,44	1	0	probably_damaging	0,92	neutral	0,11	neutral	0,58	deleterious	-5,2	deleterious	-2,92	high_impact	3,56	damaging	0,33	neutral	0,35	deleterious	3,49	23,1	0,31	0,45	NA	NA	disease	0,71	disease	0,66	disease	0,55	1	neutral	0,97	neutral	0,1	deleterious	2	deleterious	0,77	low_impact	-1,71	medium_impact	-0,3	high_impact	2,23	0,64	0,8	68,72	18,96	P	0,73	P	0,79	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7688	7688	T	C	MI.5406	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	103	35	C	R	Tgc/Cgc	-4,09	0	0	benign	0,11	neutral	0,34	neutral	1,59	neutral	-1,44	neutral	-0,7	low_impact	1,28	damaging	0,6	neutral	0,55	neutral	1,39	12,73	0,25	0,45	NA	NA	disease	0,9	disease	0,67	disease	0,77	5	neutral	0,61	deleterious	0,62	neutral	-6	neutral	0,36	medium_impact	0,13	medium_impact	0,05	medium_impact	0,1	0,35	0,8	63,44	17,24	N	0,31	N	0,64	disease_causing	0,98	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7688	7688	T	A	MI.5407	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	103	35	C	S	Tgc/Agc	-4,09	0	0	benign	0	neutral	0,52	neutral	1,67	neutral	0,23	neutral	3,88	neutral_impact	-2,03	neutral	0,85	neutral	0,95	neutral	-1,37	0	0,3	0,45	NA	NA	neutral	0,23	neutral	0,32	neutral	0,14	7	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,15	high_impact	2,08	medium_impact	0,22	low_impact	-3,01	0,58	0,8	63,44	17,24	N	0,25	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7688	7688	T	G	MI.5408	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	103	35	C	G	Tgc/Ggc	-4,09	0	0	benign	0,02	neutral	0,35	neutral	1,58	neutral	-0,62	neutral	0,14	neutral_impact	0,31	neutral	0,67	neutral	0,6	neutral	1,15	11,48	0,28	0,45	NA	NA	disease	0,69	neutral	0,47	neutral	0,37	3	neutral	0,63	deleterious	0,67	neutral	-6	neutral	0,23	medium_impact	0,86	medium_impact	0,06	medium_impact	-0,82	0,52	0,8	63,44	17,24	N	0,36	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7689	7689	G	T	MI.5409	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	104	35	C	F	tGc/tTc	5,6	1	0	benign	0,28	neutral	0,76	neutral	1,7	neutral	0,15	neutral	-1,53	neutral_impact	-0,45	neutral	0,61	neutral	0,64	deleterious	1,93	15,76	0,27	0,45	NA	NA	disease	0,83	disease	0,56	disease	0,71	4	neutral	0,18	deleterious	0,74	neutral	-6	neutral	0,36	medium_impact	-0,34	medium_impact	0,48	low_impact	-1,53	0,52	0,8	63,44	17,24	N	0,41	N	0,76	disease_causing	0,73	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8779	8779	C	A	MI.541	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	253	85	L	I	Ctc/Atc	-20	0	0	probably_damaging	0,99	neutral	0,11	neutral	4,24	neutral	-0,67	neutral	-1,83	low_impact	1,34	neutral	0,89	damaging	0,17	deleterious	4,02	23,6	0,41	0,65	neutral	0,44	disease	0,51	neutral	0,38	neutral	0,33	3	deleterious	0,99	neutral	0,06	neutral	-2	deleterious	0,73	low_impact	-2,65	medium_impact	-0,22	medium_impact	0,05	0,55	0,9	49,56	8,74	N	0,38	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7689	7689	G	A	MI.5410	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	104	35	C	Y	tGc/tAc	5,6	1	0	benign	0,28	neutral	1	neutral	1,59	neutral	-1,07	neutral	-1,53	low_impact	1,28	neutral	0,75	neutral	0,67	neutral	1,63	14,03	0,28	0,45	NA	NA	disease	0,78	disease	0,58	disease	0,72	4	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,36	medium_impact	-0,34	high_impact	1,86	medium_impact	0,1	0,47	0,8	63,44	17,24	N	0,42	N	0,76	disease_causing	0,51	0,04	.	.	.	.	.	.	COSM1636835	.	.	.	.	.	.	.	.
chrM	7689	7689	G	C	MI.5411	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	104	35	C	S	tGc/tCc	5,6	1	0	benign	0	neutral	0,52	neutral	1,67	neutral	0,23	neutral	3,88	neutral_impact	-2,03	neutral	0,85	neutral	0,95	neutral	-1,65	0	0,3	0,45	NA	NA	neutral	0,23	neutral	0,32	neutral	0,14	7	neutral	0,48	deleterious	0,76	neutral	-6	neutral	0,15	high_impact	2,08	medium_impact	0,22	low_impact	-3,01	0,58	0,8	63,44	17,24	N	0,5	N	0,06	polymorphism	0,67	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7690	7690	C	G	MI.5412	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	105	35	C	W	tgC/tgG	9,29	1	0	possibly_damaging	0,65	neutral	0,18	neutral	1,56	neutral	-1,93	neutral	-2,45	low_impact	0,94	neutral	0,64	neutral	0,52	deleterious	3,76	23,3	0,2	0,45	NA	NA	disease	0,87	disease	0,62	disease	0,77	5	neutral	0,84	neutral	0,27	neutral	-3	deleterious	0,69	medium_impact	-0,97	medium_impact	-0,16	medium_impact	-0,22	0,32	0,8	63,44	17,24	N	0,45	N	0,78	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7690	7690	C	A	MI.5413	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	105	35	C	W	tgC/tgA	9,29	1	0	possibly_damaging	0,65	neutral	0,18	neutral	1,56	neutral	-1,93	neutral	-2,45	low_impact	0,94	neutral	0,64	neutral	0,52	deleterious	4,06	23,7	0,2	0,45	NA	NA	disease	0,87	disease	0,62	disease	0,77	5	neutral	0,84	neutral	0,27	neutral	-3	deleterious	0,69	medium_impact	-0,97	medium_impact	-0,16	medium_impact	-0,22	0,32	0,8	63,44	17,24	N	0,45	N	0,78	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7691	7691	T	G	MI.5414	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	106	36	F	V	Ttc/Gtc	-0,86	0,03	0	benign	0,27	neutral	0,57	neutral	1,68	neutral	-0,56	neutral	1,71	neutral_impact	-0,64	neutral	0,75	neutral	0,75	deleterious	0,82	9,58	0,27	0,45	NA	NA	neutral	0,31	neutral	0,26	neutral	0,15	7	neutral	0,32	deleterious	0,65	neutral	-6	neutral	0,26	medium_impact	-0,32	medium_impact	0,27	low_impact	-1,71	0,57	0,8	29,52	57,04	N	0,27	N	0,69	polymorphism	0,83	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7691	7691	T	C	MI.5415	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	106	36	F	L	Ttc/Ctc	-0,86	0,03	0	benign	0,01	neutral	0,75	neutral	1,71	neutral	-0,66	neutral	0,85	neutral_impact	-0,42	neutral	0,79	neutral	0,48	deleterious	1,95	15,91	0,41	0,5	NA	NA	neutral	0,45	neutral	0,31	neutral	0,15	7	neutral	0,23	deleterious	0,87	neutral	-6	neutral	0,15	medium_impact	1,14	medium_impact	0,47	low_impact	-1,5	0,42	0,8	29,52	57,04	N	0,21	N	0,57	polymorphism	0,91	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7691	7691	T	A	MI.5416	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	106	36	F	I	Ttc/Atc	-0,86	0,03	0	benign	0,18	neutral	1	neutral	1,72	neutral	-1,25	neutral	1,27	neutral_impact	-1,09	neutral	0,71	neutral	0,78	neutral	1,06	10,97	0,25	0,45	NA	NA	neutral	0,22	neutral	0,25	neutral	0,15	7	neutral	0,18	deleterious	0,91	neutral	-6	neutral	0,23	medium_impact	-0,11	high_impact	1,86	low_impact	-2,13	0,54	0,8	29,52	57,04	N	0,24	N	0,47	polymorphism	0,91	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7692	7692	T	C	MI.5417	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	107	36	F	S	tTc/tCc	2,83	0,89	0	possibly_damaging	0,73	neutral	0,61	neutral	1,62	neutral	-2,14	neutral	2,01	neutral_impact	-1,34	neutral	0,78	neutral	0,95	deleterious	2,11	16,94	0,33	0,5	NA	NA	neutral	0,25	neutral	0,34	neutral	0,13	7	neutral	0,68	neutral	0,44	neutral	-3	deleterious	0,53	low_impact	-1,12	medium_impact	0,31	low_impact	-2,36	0,57	0,8	29,52	57,04	N	0,32	N	0,03	polymorphism	1	0,01	rs370059789	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7692	7692	T	G	MI.5418	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	107	36	F	C	tTc/tGc	2,83	0,89	0	probably_damaging	0,93	neutral	0,06	neutral	1,54	deleterious	-3,43	neutral	0,33	neutral_impact	0,44	neutral	0,64	neutral	0,44	deleterious	3,86	23,5	0,2	0,45	NA	NA	disease	0,62	neutral	0,35	neutral	0,41	2	deleterious	0,98	neutral	0,07	neutral	-2	deleterious	0,73	low_impact	-1,77	medium_impact	-0,46	medium_impact	-0,69	0,39	0,8	29,52	57,04	N	0,4	N	0,58	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7692	7692	T	A	MI.5419	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	107	36	F	Y	tTc/tAc	2,83	0,89	0	possibly_damaging	0,49	neutral	0,28	neutral	1,53	deleterious	-3,23	neutral	-0,24	low_impact	1,17	neutral	0,71	neutral	0,6	deleterious	3,76	23,4	0,27	0,45	NA	NA	neutral	0,39	neutral	0,5	neutral	0,13	7	neutral	0,69	neutral	0,4	neutral	-3	deleterious	0,51	medium_impact	-0,7	medium_impact	-0,02	medium_impact	-0,01	0,59	0,8	29,52	57,04	N	0,45	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8779	8779	C	T	MI.542	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	253	85	L	F	Ctc/Ttc	-20	0	0	probably_damaging	1	neutral	0,1	neutral	4,12	neutral	-1,38	deleterious	-3,66	medium_impact	2,04	neutral	0,93	damaging	0,16	deleterious	3,9	23,5	0,45	0,65	disease	0,7	disease	0,62	neutral	0,43	neutral	0,37	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	-0,25	medium_impact	0,65	0,51	0,9	49,56	8,74	N	0,36	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7693	7693	C	A	MI.5420	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	108	36	F	L	ttC/ttA	3,06	0,89	0	benign	0,01	neutral	0,75	neutral	1,71	neutral	-0,66	neutral	0,85	neutral_impact	-0,42	neutral	0,79	neutral	0,48	deleterious	2,56	19,85	0,41	0,5	NA	NA	neutral	0,45	neutral	0,31	neutral	0,15	7	neutral	0,23	deleterious	0,87	neutral	-6	neutral	0,15	medium_impact	1,14	medium_impact	0,47	low_impact	-1,5	0,42	0,8	29,52	57,04	N	0,23	N	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7693	7693	C	G	MI.5421	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	108	36	F	L	ttC/ttG	3,06	0,89	0	benign	0,01	neutral	0,75	neutral	1,71	neutral	-0,66	neutral	0,85	neutral_impact	-0,42	neutral	0,79	neutral	0,48	deleterious	2,23	17,71	0,41	0,5	NA	NA	neutral	0,45	neutral	0,31	neutral	0,15	7	neutral	0,23	deleterious	0,87	neutral	-6	neutral	0,15	medium_impact	1,14	medium_impact	0,47	low_impact	-1,5	0,42	0,8	29,52	57,04	N	0,23	N	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7694	7694	C	A	MI.5422	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	109	37	L	M	Cta/Ata	-7,55	0	0	probably_damaging	1	neutral	0,21	neutral	1,29	neutral	-2,15	neutral	-1,02	low_impact	1,01	neutral	0,69	neutral	0,74	deleterious	2,36	18,54	0,25	0,45	NA	NA	neutral	0,2	neutral	0,36	neutral	0,2	6	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,73	low_impact	-3,52	medium_impact	-0,11	medium_impact	-0,16	0,54	0,8	68,28	18,34	N	0,46	N	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7694	7694	C	G	MI.5423	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	109	37	L	V	Cta/Gta	-7,55	0	0	probably_damaging	0,99	neutral	0,4	neutral	1,37	neutral	-0,18	neutral	-1,91	low_impact	1,41	damaging	0,59	neutral	0,47	deleterious	2,11	16,92	0,26	0,45	NA	NA	neutral	0,35	neutral	0,37	neutral	0,16	7	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,76	low_impact	-2,58	medium_impact	0,11	medium_impact	0,22	0,52	0,8	68,28	18,34	N	0,36	N	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7695	7695	T	C	MI.5424	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	110	37	L	P	cTa/cCa	-5,24	0	0	probably_damaging	1	deleterious	0,02	neutral	1,24	deleterious	-4,08	deleterious	-5,8	medium_impact	3,23	damaging	0,38	neutral	0,29	deleterious	3,73	23,3	0,11	0,4	NA	NA	disease	0,86	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,89	low_impact	-3,52	medium_impact	-0,73	medium_impact	1,92	0,46	0,8	68,28	18,34	N	0,46	N	0,99	disease_causing	0,98	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7695	7695	T	G	MI.5425	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	110	37	L	R	cTa/cGa	-5,24	0	0	probably_damaging	1	neutral	0,08	neutral	1,25	deleterious	-3,63	deleterious	-5,03	high_impact	3,79	damaging	0,44	damaging	0,26	deleterious	3,99	23,6	0,12	0,4	NA	NA	disease	0,89	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	-0,38	high_impact	2,45	0,4	0,8	68,28	18,34	N	0,41	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7695	7695	T	A	MI.5426	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	110	37	L	Q	cTa/cAa	-5,24	0	0	probably_damaging	1	neutral	0,09	neutral	1,24	deleterious	-3,8	deleterious	-4,83	medium_impact	3,1	damaging	0,54	neutral	0,38	deleterious	3,9	23,5	0,12	0,4	NA	NA	disease	0,68	disease	0,58	disease	0,68	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	-0,35	medium_impact	1,8	0,43	0,8	68,28	18,34	N	0,34	N	0,95	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7697	7697	G	C	MI.5427	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	112	38	V	L	Gtc/Ctc	-0,63	0,1	0	benign	0,17	deleterious	0,04	neutral	0,49	deleterious	-4,09	deleterious	-2,81	medium_impact	2,73	damaging	0,35	neutral	0,41	neutral	1,53	13,45	0,33	0,5	NA	NA	disease	0,83	disease	0,6	disease	0,57	1	neutral	0,95	neutral	0,44	deleterious	1	neutral	0,33	medium_impact	-0,08	medium_impact	-0,56	medium_impact	1,45	0,34	0,8	66,96	16,57	P	0,56	P	0,23	polymorphism	0,64	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7697	7697	G	T	MI.5428	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	112	38	V	F	Gtc/Ttc	-0,63	0,1	0	probably_damaging	0,92	neutral	0,35	neutral	0,4	deleterious	-6,31	deleterious	-4,77	high_impact	3,91	damaging	0,33	neutral	0,33	deleterious	3,62	23,2	0,2	0,45	NA	NA	disease	0,92	disease	0,65	disease	0,72	4	neutral	0,93	neutral	0,22	deleterious	2	deleterious	0,84	low_impact	-1,71	medium_impact	0,06	high_impact	2,56	0,49	0,8	66,96	16,57	P	0,53	P	0,94	disease_causing	0,86	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7697	7697	G	A	MI.5429	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	112	38	V	I	Gtc/Atc	-0,63	0,1	0	benign	0,03	neutral	0,25	neutral	0,63	neutral	-2,78	neutral	-0,84	low_impact	1,68	damaging	0,59	neutral	0,57	deleterious	0,44	6,93	0,33	0,5	NA	NA	disease	0,57	disease	0,51	neutral	0,19	6	neutral	0,74	deleterious	0,61	neutral	-6	neutral	0,22	medium_impact	0,69	medium_impact	-0,06	medium_impact	0,47	0,57	0,8	66,96	16,57	P	0,55	P	0,3	polymorphism	0,86	0,03	rs879212765	.	.	.	.	.	.	.	.	G7697A	Possible HCM susceptibility	+	-	Reported	2
chrM	8780	8780	T	A	MI.543	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	254	85	L	H	cTc/cAc	-4,04	0	0	probably_damaging	1	deleterious	0,01	neutral	4,07	deleterious	-4,72	deleterious	-6,43	high_impact	3,8	neutral	0,84	damaging	0,13	deleterious	4,09	23,7	0,23	0,65	disease	0,88	disease	0,79	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,6	medium_impact	-0,84	high_impact	2,16	0,55	0,9	49,56	8,74	N	0,31	N	0,97	polymorphism	0,63	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7698	7698	T	G	MI.5430	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	113	38	V	G	gTc/gGc	6,29	1	0	probably_damaging	1	neutral	0,08	neutral	0,39	deleterious	-7,31	deleterious	-6,87	high_impact	4,46	damaging	0,37	neutral	0,43	deleterious	3,67	23,2	0,17	0,45	NA	NA	disease	0,86	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,38	high_impact	3,08	0,37	0,8	66,96	16,57	P	0,71	P	0,84	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7698	7698	T	A	MI.5431	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	113	38	V	D	gTc/gAc	6,29	1	0	probably_damaging	1	deleterious	0,01	neutral	0,39	deleterious	-8,09	deleterious	-6,8	high_impact	4,46	damaging	0,35	neutral	0,31	deleterious	4,49	24,3	0,09	0,35	NA	NA	disease	0,9	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,52	medium_impact	-0,9	high_impact	3,08	0,55	0,8	66,96	16,57	P	0,7	P	0,9	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7698	7698	T	C	MI.5432	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	113	38	V	A	gTc/gCc	6,29	1	0	possibly_damaging	0,79	deleterious	0,03	neutral	0,43	deleterious	-5,28	deleterious	-3,92	high_impact	3,91	damaging	0,42	neutral	0,45	deleterious	3,31	22,9	0,28	0,45	NA	NA	disease	0,63	disease	0,66	disease	0,66	3	neutral	0,98	neutral	0,12	deleterious	5	deleterious	0,67	low_impact	-1,26	medium_impact	-0,63	high_impact	2,56	0,28	0,8	66,96	16,57	P	0,73	P	0,59	disease_causing	0,99	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7700	7700	C	G	MI.5433	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	115	39	L	V	Ctg/Gtg	-15,85	0	0	probably_damaging	0,97	neutral	0,48	neutral	1,47	neutral	-0,52	neutral	-2,37	medium_impact	2,4	damaging	0,36	damaging	0,07	deleterious	3,23	22,8	0,43	0,55	NA	NA	neutral	0,43	neutral	0,39	neutral	0,21	6	neutral	0,97	neutral	0,26	deleterious	1	deleterious	0,75	low_impact	-2,13	medium_impact	0,19	medium_impact	1,15	0,51	0,8	68,72	19,1	N	0,41	N	0,66	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7700	7700	C	A	MI.5434	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	115	39	L	M	Ctg/Atg	-15,85	0	0	probably_damaging	1	neutral	0,22	neutral	1,42	neutral	-2,11	neutral	-1,52	medium_impact	2,11	damaging	0,43	damaging	0,06	deleterious	3,55	23,1	0,29	0,45	NA	NA	neutral	0,31	neutral	0,29	neutral	0,19	6	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,74	low_impact	-3,52	medium_impact	-0,1	medium_impact	0,87	0,52	0,8	68,72	19,1	N	0,36	N	0,78	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7701	7701	T	A	MI.5435	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	116	39	L	Q	cTg/cAg	0,06	0	0	probably_damaging	1	neutral	0,13	neutral	1,4	deleterious	-3,78	deleterious	-5,16	high_impact	3,9	damaging	0,35	damaging	0,04	deleterious	4,02	23,6	0,19	0,45	NA	NA	disease	0,63	neutral	0,42	neutral	0,47	1	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,79	low_impact	-3,52	medium_impact	-0,25	high_impact	2,55	0,58	0,8	68,72	19,1	N	0,42	N	0,95	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7701	7701	T	C	MI.5436	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	116	39	L	P	cTg/cCg	0,06	0	0	probably_damaging	1	neutral	0,09	neutral	1,38	deleterious	-4,33	deleterious	-6,11	high_impact	3,9	damaging	0,14	damaging	0,02	deleterious	3,71	23,3	0,15	0,4	NA	NA	disease	0,86	disease	0,59	disease	0,71	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,35	high_impact	2,55	0,57	0,8	68,72	19,1	P	0,71	P	0,99	polymorphism	0,76	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7701	7701	T	G	MI.5437	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	116	39	L	R	cTg/cGg	0,06	0	0	probably_damaging	1	neutral	0,15	neutral	1,4	deleterious	-3,63	deleterious	-5,23	high_impact	3,9	damaging	0,19	damaging	0,02	deleterious	4,01	23,6	0,18	0,45	NA	NA	disease	0,87	disease	0,56	disease	0,69	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,21	high_impact	2,55	0,56	0,8	68,72	19,1	P	0,7	P	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7703	7703	T	G	MI.5438	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	118	40	Y	D	Tat/Gat	-20	0	0	probably_damaging	1	deleterious	0,02	neutral	1,33	deleterious	-4	deleterious	-9,75	high_impact	3,83	damaging	0,18	damaging	0,03	deleterious	3,77	23,4	0,3	0,45	NA	NA	disease	0,91	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-3,52	medium_impact	-0,73	high_impact	2,49	0,28	0,8	68,28	19,11	P	0,48	N	0,99	polymorphism	0,99	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7703	7703	T	A	MI.5439	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	118	40	Y	N	Tat/Aat	-20	0	0	probably_damaging	1	deleterious	0,03	neutral	1,34	deleterious	-3,16	deleterious	-8,76	high_impact	4,03	damaging	0,15	damaging	0,02	deleterious	3,85	23,4	0,43	0,55	NA	NA	disease	0,89	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,89	low_impact	-3,52	medium_impact	-0,63	high_impact	2,67	0,26	0,8	68,28	19,11	P	0,51	P	0,99	polymorphism	0,99	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8780	8780	T	G	MI.544	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	254	85	L	R	cTc/cGc	-4,04	0	0	probably_damaging	1	deleterious	0,01	neutral	4,08	deleterious	-4,19	deleterious	-5,51	high_impact	4,14	neutral	0,85	damaging	0,13	deleterious	4,13	23,8	0,23	0,65	disease	0,84	disease	0,87	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,6	medium_impact	-0,84	high_impact	2,45	0,62	0,9	49,56	8,74	N	0,33	N	0,99	disease_causing	0,52	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7703	7703	T	C	MI.5440	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	118	40	Y	H	Tat/Cat	-20	0	0	probably_damaging	1	neutral	0,18	neutral	1,34	deleterious	-3,51	deleterious	-4,79	high_impact	4,03	damaging	0,15	damaging	0,03	deleterious	3,34	22,9	0,48	0,55	NA	NA	disease	0,87	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	-0,16	high_impact	2,67	0,33	0,8	68,28	19,11	P	0,54	P	0,94	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7704	7704	A	C	MI.5441	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	119	40	Y	S	tAt/tCt	7,44	1	0	probably_damaging	1	neutral	0,13	neutral	1,37	neutral	-1,72	deleterious	-8,78	medium_impact	3,34	damaging	0,13	damaging	0,03	deleterious	3,71	23,3	0,35	0,5	NA	NA	disease	0,87	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,88	low_impact	-3,52	medium_impact	-0,25	high_impact	2,03	0,33	0,8	68,28	19,11	P	0,82	P	0,99	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7704	7704	A	G	MI.5442	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	119	40	Y	C	tAt/tGt	7,44	1	0	probably_damaging	1	neutral	0,06	neutral	1,35	deleterious	-3,4	deleterious	-8,8	high_impact	3,57	damaging	0,13	damaging	0,02	deleterious	3,43	23	0,43	0,55	NA	NA	disease	0,9	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,46	high_impact	2,24	0,16	0,8	68,28	19,11	P	0,82	P	0,96	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7704	7704	A	T	MI.5443	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	119	40	Y	F	tAt/tTt	7,44	1	0	probably_damaging	0,98	neutral	0,31	neutral	1,39	neutral	0,18	deleterious	-3,92	medium_impact	2,45	damaging	0,16	damaging	0,02	deleterious	3,34	22,9	0,34	0,5	NA	NA	disease	0,82	neutral	0,45	neutral	0,19	6	deleterious	0,98	neutral	0,17	deleterious	1	deleterious	0,87	low_impact	-2,3	medium_impact	0,01	medium_impact	1,19	0,28	0,8	68,28	19,11	P	0,87	P	0,87	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7706	7706	G	A	MI.5444	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	121	41	A	T	Gcc/Acc	-2,48	0	0	possibly_damaging	0,46	neutral	0,41	neutral	1,53	neutral	-0,85	neutral	0,32	neutral_impact	-0,55	neutral	0,83	neutral	0,75	neutral	1,28	12,17	0,57	0,65	NA	NA	neutral	0,17	neutral	0,29	neutral	0,22	6	neutral	0,55	deleterious	0,48	neutral	-3	neutral	0,38	medium_impact	-0,66	medium_impact	0,12	low_impact	-1,62	0,77	0,85	28,63	41,18	N	0,35	N	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	G7706A	Alpers-Huttennlocher-like	-	+	Reported	1
chrM	7706	7706	G	T	MI.5445	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	121	41	A	S	Gcc/Tcc	-2,48	0	0	possibly_damaging	0,62	neutral	0,35	neutral	1,53	neutral	-0,97	neutral	-0,72	neutral_impact	0,05	neutral	0,71	neutral	0,68	deleterious	3,16	22,6	0,53	0,6	NA	NA	neutral	0,3	neutral	0,29	neutral	0,16	7	neutral	0,69	neutral	0,37	neutral	-3	deleterious	0,46	medium_impact	-0,92	medium_impact	0,06	low_impact	-1,06	0,8	0,85	28,63	41,18	N	0,4	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7706	7706	G	C	MI.5446	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	121	41	A	P	Gcc/Ccc	-2,48	0	0	possibly_damaging	0,9	neutral	0,17	neutral	1,48	neutral	-2,77	neutral	-1,95	low_impact	1,52	damaging	0,53	neutral	0,38	deleterious	3,61	23,2	0,24	0,45	NA	NA	disease	0,78	disease	0,67	disease	0,74	5	neutral	0,95	neutral	0,14	neutral	-3	deleterious	0,8	low_impact	-1,61	medium_impact	-0,18	medium_impact	0,32	0,86	0,9	28,63	41,18	N	0,33	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7707	7707	C	A	MI.5447	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	122	41	A	D	gCc/gAc	0,75	0,09	0	possibly_damaging	0,86	neutral	0,21	neutral	1,47	deleterious	-3,23	neutral	-2,12	low_impact	1,52	damaging	0,58	neutral	0,45	deleterious	4,21	23,9	0,26	0,45	NA	NA	disease	0,69	disease	0,66	disease	0,71	4	neutral	0,91	neutral	0,18	neutral	-3	deleterious	0,72	low_impact	-1,46	medium_impact	-0,11	medium_impact	0,32	0,7	0,85	28,63	41,18	N	0,39	N	0,74	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7707	7707	C	G	MI.5448	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	122	41	A	G	gCc/gGc	0,75	0,09	0	possibly_damaging	0,69	neutral	0,24	neutral	1,5	neutral	-1,8	deleterious	-2,58	low_impact	1,18	neutral	0,68	neutral	0,66	deleterious	2,5	19,47	0,46	0,55	NA	NA	neutral	0,38	neutral	0,41	neutral	0,15	7	neutral	0,81	neutral	0,28	neutral	-3	deleterious	0,54	low_impact	-1,04	medium_impact	-0,07	medium_impact	0	0,76	0,85	28,63	41,18	N	0,47	N	0,68	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7707	7707	C	T	MI.5449	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	122	41	A	V	gCc/gTc	0,75	0,09	0	benign	0,02	neutral	0,44	neutral	1,68	neutral	0,87	neutral	2,59	neutral_impact	-0,42	neutral	0,9	neutral	0,93	neutral	1,09	11,19	0,58	0,65	NA	NA	neutral	0,28	neutral	0,3	neutral	0,16	7	neutral	0,54	deleterious	0,71	neutral	-6	neutral	0,17	medium_impact	0,86	medium_impact	0,15	low_impact	-1,5	0,82	0,85	28,63	41,18	N	0,38	N	0,39	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8780	8780	T	C	MI.545	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	254	85	L	P	cTc/cCc	-4,04	0	0	probably_damaging	1	deleterious	0,01	neutral	4,07	deleterious	-3,91	deleterious	-6,47	high_impact	3,8	neutral	0,83	damaging	0,14	deleterious	3,84	23,4	0,17	0,65	disease	0,88	disease	0,81	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,6	medium_impact	-0,84	high_impact	2,16	0,58	0,9	49,56	8,74	N	0,31	N	1	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7709	7709	C	G	MI.5450	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	124	42	L	V	Ctt/Gtt	-2,94	0	0	probably_damaging	0,99	neutral	0,47	neutral	1,14	neutral	-2,49	neutral	0,42	low_impact	1,72	damaging	0,53	damaging	0,27	deleterious	3,32	22,9	0,55	0,6	NA	NA	neutral	0,39	disease	0,56	neutral	0,35	3	deleterious	0,99	neutral	0,24	neutral	-2	deleterious	0,78	low_impact	-2,58	medium_impact	0,18	medium_impact	0,51	0,75	0,85	28,19	63,57	N	0,41	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7709	7709	C	A	MI.5451	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	124	42	L	I	Ctt/Att	-2,94	0	0	probably_damaging	0,99	neutral	0,7	neutral	1,22	neutral	-1,63	neutral	1,33	neutral_impact	-0,87	neutral	0,75	neutral	0,97	neutral	1,3	12,25	0,51	0,6	NA	NA	neutral	0,08	neutral	0,27	neutral	0,22	6	deleterious	0,99	neutral	0,36	neutral	-2	deleterious	0,73	low_impact	-2,58	medium_impact	0,41	low_impact	-1,92	0,72	0,85	28,19	63,57	N	0,33	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7709	7709	C	T	MI.5452	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	124	42	L	F	Ctt/Ttt	-2,94	0	0	probably_damaging	1	neutral	0,55	neutral	1,11	neutral	-2,8	neutral	-2,21	low_impact	1,22	damaging	0,48	damaging	0,25	deleterious	3,79	23,4	0,53	0,6	NA	NA	disease	0,55	neutral	0,4	neutral	0,38	2	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,8	low_impact	-3,52	medium_impact	0,25	medium_impact	0,04	0,75	0,85	28,19	63,57	N	0,32	N	0,35	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7710	7710	T	A	MI.5453	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	125	42	L	H	cTt/cAt	1,21	0,51	0	probably_damaging	1	neutral	0,19	neutral	1,03	deleterious	-5,61	deleterious	-5,03	medium_impact	2,35	damaging	0,53	damaging	0,2	deleterious	3,87	23,5	0,29	0,45	NA	NA	disease	0,62	disease	0,52	disease	0,57	1	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,81	low_impact	-3,52	medium_impact	-0,14	medium_impact	1,1	0,61	0,8	28,19	63,57	N	0,34	N	0,82	disease_causing	0,74	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7710	7710	T	G	MI.5454	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	125	42	L	R	cTt/cGt	1,21	0,51	0	probably_damaging	1	neutral	0,12	neutral	1,04	deleterious	-5,02	deleterious	-4,88	medium_impact	2,35	damaging	0,44	damaging	0,18	deleterious	3,97	23,6	0,34	0,5	NA	NA	disease	0,86	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,89	low_impact	-3,52	medium_impact	-0,27	medium_impact	1,1	0,66	0,8	28,19	63,57	N	0,42	N	0,93	disease_causing	0,84	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7710	7710	T	C	MI.5455	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	125	42	L	P	cTt/cCt	1,21	0,51	0	probably_damaging	1	neutral	0,07	neutral	1,03	deleterious	-5,59	deleterious	-5,03	medium_impact	2,69	damaging	0,42	damaging	0,18	deleterious	3,61	23,2	0,26	0,45	NA	NA	disease	0,85	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,9	low_impact	-3,52	medium_impact	-0,42	medium_impact	1,42	0,7	0,85	28,19	63,57	N	0,44	N	0,97	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7712	7712	T	C	MI.5456	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	127	43	F	L	Ttc/Ctc	-2,24	0	0	benign	0	neutral	0,66	neutral	1,68	neutral	-0,48	neutral	1,01	neutral_impact	-0,46	neutral	0,81	neutral	0,75	neutral	-0,07	1,94	0,54	0,6	NA	NA	neutral	0,27	neutral	0,26	neutral	0,16	7	neutral	0,33	deleterious	0,83	neutral	-6	neutral	0,12	high_impact	2,08	medium_impact	0,36	low_impact	-1,54	0,43	0,8	30,84	24,7	N	0,27	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7712	7712	T	A	MI.5457	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	127	43	F	I	Ttc/Atc	-2,24	0	0	benign	0,09	neutral	0,92	neutral	1,63	neutral	-0,58	neutral	1,48	neutral_impact	-0,66	neutral	0,75	neutral	0,85	deleterious	0,28	5,48	0,29	0,45	NA	NA	neutral	0,12	neutral	0,23	neutral	0,23	5	neutral	0,03	deleterious	0,92	neutral	-6	neutral	0,17	medium_impact	0,22	medium_impact	0,79	low_impact	-1,72	0,39	0,8	30,84	24,7	N	0,27	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7712	7712	T	G	MI.5458	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	127	43	F	V	Ttc/Gtc	-2,24	0	0	benign	0,14	neutral	0,61	neutral	1,76	neutral	-0,77	neutral	1,9	neutral_impact	-0,67	neutral	0,78	neutral	0,87	neutral	-0,64	0,1	0,39	0,5	NA	NA	neutral	0,23	neutral	0,26	neutral	0,16	7	neutral	0,28	deleterious	0,74	neutral	-6	neutral	0,19	medium_impact	0,01	medium_impact	0,31	low_impact	-1,73	0,32	0,8	30,84	24,7	N	0,23	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7713	7713	T	A	MI.5459	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	128	43	F	Y	tTc/tAc	-0,63	0	0	benign	0,42	neutral	0,47	neutral	1,53	neutral	-2,27	neutral	-0,23	low_impact	0,81	neutral	0,73	neutral	0,6	deleterious	0,51	7,5	0,34	0,5	NA	NA	neutral	0,31	neutral	0,33	neutral	0,15	7	neutral	0,48	deleterious	0,53	neutral	-6	neutral	0,41	medium_impact	-0,59	medium_impact	0,18	medium_impact	-0,35	0,39	0,8	30,84	24,7	N	0,38	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8782	8782	G	C	MI.546	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	256	86	G	R	Gga/Cga	0,13	0,93	0	probably_damaging	1	deleterious	0	neutral	3,68	deleterious	-6,97	deleterious	-7,35	high_impact	4,23	damaging	0,55	damaging	0,08	deleterious	3,82	23,4	0,21	0,65	disease	0,85	disease	0,89	disease	0,83	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,6	low_impact	-1,4	high_impact	2,53	0,87	0,9	50,44	8,61	N	0,47	N	0,98	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7713	7713	T	G	MI.5460	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	128	43	F	C	tTc/tGc	-0,63	0	0	possibly_damaging	0,74	neutral	0,16	neutral	1,51	deleterious	-3,74	neutral	0,33	low_impact	1,65	neutral	0,67	neutral	0,44	deleterious	2,55	19,77	0,29	0,45	NA	NA	disease	0,6	neutral	0,47	neutral	0,47	1	neutral	0,88	neutral	0,21	neutral	-3	deleterious	0,59	low_impact	-1,14	medium_impact	-0,19	medium_impact	0,44	0,27	0,8	30,84	24,7	N	0,43	N	0,35	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7713	7713	T	C	MI.5461	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	128	43	F	S	tTc/tCc	-0,63	0	0	benign	0,01	neutral	0,51	neutral	1,56	neutral	-2,29	neutral	1,84	neutral_impact	-0,4	neutral	0,87	neutral	0,97	neutral	-0,14	1,45	0,46	0,55	NA	NA	neutral	0,24	neutral	0,35	neutral	0,14	7	neutral	0,47	deleterious	0,75	neutral	-6	neutral	0,14	medium_impact	1,14	medium_impact	0,21	low_impact	-1,48	0,34	0,8	30,84	24,7	N	0,3	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7714	7714	C	G	MI.5462	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	129	43	F	L	ttC/ttG	0,75	0	0	benign	0	neutral	0,66	neutral	1,68	neutral	-0,48	neutral	1,01	neutral_impact	-0,46	neutral	0,81	neutral	0,75	deleterious	0,3	5,71	0,54	0,6	NA	NA	neutral	0,27	neutral	0,26	neutral	0,16	7	neutral	0,33	deleterious	0,83	neutral	-6	neutral	0,12	high_impact	2,08	medium_impact	0,36	low_impact	-1,54	0,43	0,8	30,84	24,7	N	0,29	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7714	7714	C	A	MI.5463	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	129	43	F	L	ttC/ttA	0,75	0	0	benign	0	neutral	0,66	neutral	1,68	neutral	-0,48	neutral	1,01	neutral_impact	-0,46	neutral	0,81	neutral	0,75	deleterious	0,63	8,37	0,54	0,6	NA	NA	neutral	0,27	neutral	0,26	neutral	0,16	7	neutral	0,33	deleterious	0,83	neutral	-6	neutral	0,12	high_impact	2,08	medium_impact	0,36	low_impact	-1,54	0,43	0,8	30,84	24,7	N	0,29	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7715	7715	C	G	MI.5464	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	130	44	L	V	Cta/Gta	-4,55	0	0	benign	0,11	neutral	0,73	neutral	1,56	neutral	-0,33	neutral	-0,4	neutral_impact	0,79	neutral	0,78	neutral	0,8	neutral	-0,17	1,29	0,62	0,65	NA	NA	neutral	0,19	neutral	0,34	neutral	0,18	6	neutral	0,16	deleterious	0,81	neutral	-6	neutral	0,18	medium_impact	0,13	medium_impact	0,44	medium_impact	-0,37	0,39	0,8	28,19	26,29	N	0,25	N	0,39	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7715	7715	C	A	MI.5465	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	130	44	L	M	Cta/Ata	-4,55	0	0	possibly_damaging	0,8	neutral	0,8	neutral	1,5	neutral	-1,16	neutral	-0,35	neutral_impact	0,68	neutral	0,75	neutral	0,81	deleterious	1,89	15,53	0,32	0,5	NA	NA	neutral	0,06	neutral	0,22	neutral	0,2	6	neutral	0,77	deleterious	0,5	neutral	-3	deleterious	0,57	low_impact	-1,28	medium_impact	0,54	medium_impact	-0,47	0,61	0,8	28,19	26,29	N	0,33	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7716	7716	T	A	MI.5466	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	131	44	L	Q	cTa/cAa	-1,55	0	0	probably_damaging	0,94	neutral	0,35	neutral	1,47	neutral	-2,06	neutral	-1,85	medium_impact	2,77	neutral	0,69	neutral	0,46	deleterious	2,65	20,5	0,18	0,45	NA	NA	neutral	0,5	neutral	0,39	neutral	0,49	0	neutral	0,94	neutral	0,21	deleterious	1	deleterious	0,73	low_impact	-1,83	medium_impact	0,06	medium_impact	1,49	0,55	0,8	28,19	26,29	N	0,41	N	0,88	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7716	7716	T	G	MI.5467	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	131	44	L	R	cTa/cGa	-1,55	0	0	possibly_damaging	0,86	neutral	0,3	neutral	1,51	neutral	-1,04	neutral	-2,11	low_impact	0,88	neutral	0,61	neutral	0,35	deleterious	2,64	20,5	0,18	0,45	NA	NA	disease	0,68	disease	0,53	neutral	0,49	0	neutral	0,89	neutral	0,22	neutral	-3	deleterious	0,77	low_impact	-1,46	medium_impact	0	medium_impact	-0,28	0,54	0,8	28,19	26,29	N	0,29	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7716	7716	T	C	MI.5468	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	131	44	L	P	cTa/cCa	-1,55	0	0	probably_damaging	0,95	neutral	0,18	neutral	1,47	neutral	-2,33	neutral	-2,42	medium_impact	2,21	neutral	0,6	neutral	0,34	deleterious	2,57	19,91	0,08	0,35	NA	NA	disease	0,76	disease	0,56	disease	0,7	4	neutral	0,97	neutral	0,12	deleterious	1	deleterious	0,82	low_impact	-1,91	medium_impact	-0,16	medium_impact	0,97	0,52	0,8	28,19	26,29	N	0,3	N	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7718	7718	A	G	MI.5469	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	133	45	T	A	Aca/Gca	-20	0	0	benign	0,27	neutral	0,17	neutral	1,61	neutral	0,3	neutral	-0,82	neutral_impact	0,28	neutral	0,76	neutral	0,75	neutral	1,32	12,36	0,68	0,7	NA	NA	neutral	0,26	neutral	0,47	neutral	0,16	7	neutral	0,8	neutral	0,45	neutral	-6	neutral	0,25	medium_impact	-0,32	medium_impact	-0,18	medium_impact	-0,84	0,48	0,8	28,19	66,11	N	0,41	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8782	8782	G	T	MI.547	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	256	86	G	W	Gga/Tga	0,13	0,93	0	probably_damaging	1	deleterious	0	neutral	3,66	deleterious	-10,28	deleterious	-7,39	high_impact	4,58	damaging	0,59	damaging	0,08	deleterious	4,33	24	0,16	0,65	disease	0,99	disease	0,87	disease	0,78	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	high_impact	2,83	0,43	0,9	50,44	8,61	N	0,46	N	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7718	7718	A	C	MI.5470	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	133	45	T	P	Aca/Cca	-20	0	0	possibly_damaging	0,8	neutral	0,12	neutral	1,5	neutral	-2,58	neutral	-2,01	low_impact	1,42	neutral	0,62	neutral	0,4	deleterious	2,99	22,2	0,29	0,45	NA	NA	disease	0,83	disease	0,7	disease	0,78	6	neutral	0,93	neutral	0,16	neutral	-3	deleterious	0,77	low_impact	-1,28	medium_impact	-0,27	medium_impact	0,23	0,63	0,8	28,19	66,11	N	0,32	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7718	7718	A	T	MI.5471	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	133	45	T	S	Aca/Tca	-20	0	0	benign	0,41	neutral	0,18	neutral	1,53	neutral	-1,03	neutral	-0,88	neutral_impact	0,46	neutral	0,67	neutral	0,64	neutral	1,36	12,59	0,69	0,75	NA	NA	neutral	0,37	neutral	0,34	neutral	0,15	7	neutral	0,79	neutral	0,39	neutral	-6	neutral	0,33	medium_impact	-0,57	medium_impact	-0,16	medium_impact	-0,67	0,62	0,8	28,19	66,11	N	0,44	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7719	7719	C	T	MI.5472	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	134	45	T	M	aCa/aTa	5,6	1	0	benign	0,08	neutral	0,68	neutral	1,65	neutral	0,7	neutral	3,25	neutral_impact	-1,72	neutral	0,73	neutral	0,97	neutral	-0,81	0,04	0,42	0,55	NA	NA	neutral	0,16	neutral	0,31	neutral	0,2	6	neutral	0,22	deleterious	0,8	neutral	-6	neutral	0,16	medium_impact	0,27	medium_impact	0,39	low_impact	-2,72	0,68	0,85	28,19	66,11	P	0,52	P	0,03	polymorphism	0,62	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7719	7719	C	A	MI.5473	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	134	45	T	K	aCa/aAa	5,6	1	0	possibly_damaging	0,53	neutral	0,05	neutral	1,51	neutral	-1,88	neutral	-1,22	medium_impact	2,11	neutral	0,61	neutral	0,52	deleterious	2,63	20,4	0,37	0,5	NA	NA	disease	0,71	disease	0,66	disease	0,72	4	neutral	0,95	neutral	0,26	NA	0	deleterious	0,49	medium_impact	-0,77	medium_impact	-0,5	medium_impact	0,87	0,62	0,8	28,19	66,11	P	0,58	P	0,48	disease_causing	0,53	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7721	7721	C	G	MI.5474	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	136	46	L	V	Ctc/Gtc	-0,17	0	0	probably_damaging	0,99	neutral	0,45	neutral	1,41	neutral	-0,94	neutral	-0,33	low_impact	0,8	neutral	0,78	neutral	0,68	deleterious	0,74	9,1	0,6	0,65	NA	NA	neutral	0,17	neutral	0,34	neutral	0,22	6	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,72	low_impact	-2,58	medium_impact	0,16	medium_impact	-0,36	0,71	0,85	68,72	18,95	N	0,32	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7721	7721	C	T	MI.5475	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	136	46	L	F	Ctc/Ttc	-0,17	0	0	probably_damaging	1	neutral	0,39	neutral	1,29	neutral	-2,11	deleterious	-2,61	low_impact	1,07	damaging	0,55	damaging	0,17	deleterious	2,42	18,92	0,64	0,7	NA	NA	neutral	0,12	neutral	0,3	neutral	0,2	6	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,72	low_impact	-3,52	medium_impact	0,1	medium_impact	-0,1	0,6	0,8	68,72	18,95	N	0,36	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7721	7721	C	A	MI.5476	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	136	46	L	I	Ctc/Atc	-0,17	0	0	probably_damaging	1	neutral	0,72	neutral	1,41	neutral	-0,92	neutral	-0,13	low_impact	0,87	neutral	0,69	neutral	0,54	deleterious	2,38	18,67	0,54	0,6	NA	NA	neutral	0,14	neutral	0,29	neutral	0,23	6	deleterious	0,99	neutral	0,36	neutral	-2	deleterious	0,72	low_impact	-3,52	medium_impact	0,43	medium_impact	-0,29	0,7	0,85	68,72	18,95	N	0,29	N	0,63	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7722	7722	T	A	MI.5477	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	137	46	L	H	cTc/cAc	-1,78	0	0	probably_damaging	1	neutral	0,06	neutral	1,21	deleterious	-4,57	deleterious	-4,92	high_impact	3,58	damaging	0,49	damaging	0,17	deleterious	4,11	23,7	0,34	0,5	NA	NA	disease	0,58	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,79	low_impact	-3,52	medium_impact	-0,46	high_impact	2,25	0,65	0,8	68,72	18,95	N	0,36	N	0,94	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7722	7722	T	G	MI.5478	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	137	46	L	R	cTc/cGc	-1,78	0	0	probably_damaging	1	neutral	0,1	neutral	1,22	deleterious	-4,01	deleterious	-4,42	high_impact	3,58	damaging	0,3	damaging	0,13	deleterious	4,03	23,7	0,39	0,5	NA	NA	disease	0,78	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	-0,32	high_impact	2,25	0,57	0,8	68,72	18,95	P	0,5	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7722	7722	T	C	MI.5479	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	137	46	L	P	cTc/cCc	-1,78	0	0	probably_damaging	1	deleterious	0,02	neutral	1,21	deleterious	-4,6	deleterious	-4,76	medium_impact	3,23	damaging	0,3	damaging	0,09	deleterious	3,81	23,4	0,47	0,55	NA	NA	disease	0,81	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,87	low_impact	-3,52	medium_impact	-0,73	medium_impact	1,92	0,62	0,8	68,72	18,95	N	0,46	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8783	8783	G	T	MI.548	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	257	86	G	V	gGa/gTa	7,07	1	0	probably_damaging	1	deleterious	0	neutral	3,67	deleterious	-6,63	deleterious	-8,27	high_impact	4,58	damaging	0,55	damaging	0,09	deleterious	3,68	23,3	0,19	0,65	disease	0,92	disease	0,84	disease	0,77	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,83	0,56	0,9	50,44	8,61	P	0,55	P	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7724	7724	A	C	MI.5480	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	139	47	T	P	Aca/Cca	-2,01	0	0	possibly_damaging	0,75	neutral	0,12	neutral	1,49	neutral	-2,6	deleterious	-4,51	medium_impact	2,73	damaging	0,49	neutral	0,31	deleterious	3,18	22,7	0,43	0,55	NA	NA	disease	0,82	disease	0,59	disease	0,7	4	neutral	0,91	neutral	0,19	NA	0	deleterious	0,77	low_impact	-1,17	medium_impact	-0,27	medium_impact	1,45	0,8	0,85	66,52	17,39	N	0,35	N	0,9	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7724	7724	A	G	MI.5481	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	139	47	T	A	Aca/Gca	-2,01	0	0	benign	0,09	neutral	0,41	neutral	1,56	neutral	-0,36	deleterious	-3,67	medium_impact	2,47	neutral	0,69	neutral	0,67	neutral	1,39	12,74	0,71	0,75	NA	NA	neutral	0,3	neutral	0,39	neutral	0,16	7	neutral	0,53	deleterious	0,66	neutral	-3	neutral	0,19	medium_impact	0,22	medium_impact	0,12	medium_impact	1,21	0,59	0,8	66,52	17,39	N	0,43	N	0,65	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7724	7724	A	T	MI.5482	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	139	47	T	S	Aca/Tca	-2,01	0	0	benign	0,16	neutral	0,45	neutral	1,54	neutral	-0,79	neutral	-2,43	neutral_impact	0,4	neutral	0,78	neutral	0,81	neutral	-0,53	0,19	0,73	0,75	NA	NA	neutral	0,27	neutral	0,3	neutral	0,17	7	neutral	0,46	deleterious	0,65	neutral	-6	neutral	0,22	medium_impact	-0,05	medium_impact	0,16	medium_impact	-0,73	0,81	0,85	66,52	17,39	N	0,3	N	0,8	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7725	7725	C	T	MI.5483	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	140	47	T	M	aCa/aTa	1,44	0,02	0	benign	0,13	neutral	0,38	neutral	1,56	neutral	-0,36	deleterious	-4,54	low_impact	1,42	neutral	0,79	neutral	0,74	neutral	0,95	10,36	0,6	0,65	NA	NA	neutral	0,41	neutral	0,34	neutral	0,14	7	neutral	0,56	deleterious	0,63	neutral	-6	neutral	0,21	medium_impact	0,05	medium_impact	0,09	medium_impact	0,23	0,71	0,85	66,52	17,39	N	0,37	N	0,92	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7725	7725	C	A	MI.5484	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	140	47	T	K	aCa/aAa	1,44	0,02	0	benign	0,27	neutral	0,17	neutral	1,52	neutral	-1,06	deleterious	-4,56	low_impact	1,28	neutral	0,62	neutral	0,36	deleterious	2,57	19,94	0,52	0,6	NA	NA	disease	0,67	disease	0,56	neutral	0,27	5	neutral	0,8	neutral	0,45	neutral	-6	deleterious	0,54	medium_impact	-0,32	medium_impact	-0,18	medium_impact	0,1	0,61	0,8	66,52	17,39	N	0,34	N	0,94	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7727	7727	A	C	MI.5485	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	142	48	T	P	Aca/Cca	-4,09	0	0	probably_damaging	1	neutral	0,27	neutral	1,49	neutral	-2,12	deleterious	-4,69	medium_impact	2,78	damaging	0,33	damaging	0,1	deleterious	3,31	22,9	0,4	0,5	NA	NA	disease	0,88	disease	0,68	disease	0,75	5	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,87	low_impact	-3,52	medium_impact	-0,03	medium_impact	1,5	0,59	0,8	67,84	19,05	N	0,44	N	0,9	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7727	7727	A	T	MI.5486	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	142	48	T	S	Aca/Tca	-4,09	0	0	probably_damaging	0,99	neutral	0,79	neutral	1,6	neutral	0,18	deleterious	-2,63	low_impact	1,2	damaging	0,55	damaging	0,15	deleterious	2,05	16,55	0,71	0,75	NA	NA	disease	0,52	neutral	0,32	neutral	0,2	6	deleterious	0,98	neutral	0,4	neutral	-2	deleterious	0,75	low_impact	-2,58	medium_impact	0,52	medium_impact	0,02	0,78	0,85	67,84	19,05	N	0,24	N	0,8	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7727	7727	A	G	MI.5487	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	142	48	T	A	Aca/Gca	-4,09	0	0	probably_damaging	0,99	neutral	0,76	neutral	1,56	neutral	-0,36	deleterious	-3,24	medium_impact	2,08	neutral	0,65	neutral	0,41	deleterious	2,21	17,61	0,73	0,75	NA	NA	neutral	0,41	neutral	0,42	neutral	0,14	7	deleterious	0,98	neutral	0,39	deleterious	1	deleterious	0,72	low_impact	-2,58	medium_impact	0,48	medium_impact	0,85	0,64	0,8	67,84	19,05	N	0,24	N	0,65	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7728	7728	C	T	MI.5488	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	143	48	T	M	aCa/aTa	3,98	0,99	0	probably_damaging	1	neutral	0,15	neutral	1,49	neutral	-2,62	deleterious	-4,66	medium_impact	2,15	damaging	0,49	damaging	0,08	deleterious	3,82	23,4	0,64	0,7	NA	NA	disease	0,68	neutral	0,47	neutral	0,39	2	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,77	low_impact	-3,52	medium_impact	-0,21	medium_impact	0,91	0,7	0,85	67,84	19,05	N	0,42	N	0,92	polymorphism	0,57	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7728	7728	C	A	MI.5489	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	143	48	T	K	aCa/aAa	3,98	0,99	0	probably_damaging	1	neutral	0,89	neutral	1,59	neutral	0,09	deleterious	-4,53	low_impact	1,84	damaging	0,42	damaging	0,03	deleterious	4,36	24,1	0,52	0,6	NA	NA	disease	0,81	neutral	0,41	disease	0,63	3	deleterious	1	neutral	0,45	neutral	-2	deleterious	0,83	low_impact	-3,52	medium_impact	0,71	medium_impact	0,62	0,79	0,85	67,84	19,05	N	0,48	N	0,94	disease_causing	0,58	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8783	8783	G	A	MI.549	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	257	86	G	E	gGa/gAa	7,07	1	0	probably_damaging	1	deleterious	0	neutral	3,73	deleterious	-5,88	deleterious	-7,34	high_impact	4,58	neutral	0,61	damaging	0,08	deleterious	3,77	23,4	0,27	0,65	disease	0,87	disease	0,86	disease	0,83	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,83	0,74	0,9	50,44	8,61	P	0,59	P	1	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7730	7730	A	C	MI.5490	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	145	49	K	Q	Aaa/Caa	-2,94	0	0	benign	0,13	neutral	0,28	neutral	1,41	neutral	-2,28	neutral	-2,49	medium_impact	2,84	damaging	0,57	neutral	0,48	neutral	1,44	13,02	0,65	0,7	NA	NA	disease	0,74	neutral	0,4	neutral	0,16	7	neutral	0,68	deleterious	0,58	neutral	-3	neutral	0,25	medium_impact	0,05	medium_impact	-0,02	medium_impact	1,56	0,75	0,85	67,4	17,16	N	0,42	N	0,9	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7730	7730	A	G	MI.5491	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	145	49	K	E	Aaa/Gaa	-2,94	0	0	benign	0,08	neutral	0,26	neutral	1,41	neutral	-1,63	deleterious	-2,54	medium_impact	2,84	damaging	0,58	neutral	0,75	deleterious	1,99	16,16	0,53	0,6	NA	NA	disease	0,83	disease	0,67	disease	0,55	1	neutral	0,71	deleterious	0,59	neutral	-3	neutral	0,28	medium_impact	0,27	medium_impact	-0,05	medium_impact	1,56	0,71	0,85	67,4	17,16	N	0,38	N	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7731	7731	A	T	MI.5492	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	146	49	K	M	aAa/aTa	6,98	1	0	possibly_damaging	0,66	neutral	0,2	neutral	1,39	deleterious	-4,59	deleterious	-4,1	medium_impact	3,42	damaging	0,52	neutral	0,45	deleterious	3,43	23	0,37	0,5	NA	NA	disease	0,73	disease	0,56	disease	0,51	0	neutral	0,82	neutral	0,27	NA	0	neutral	0,42	medium_impact	-0,99	medium_impact	-0,13	high_impact	2,1	0,51	0,8	67,4	17,16	P	0,58	P	0,75	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7731	7731	A	C	MI.5493	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	146	49	K	T	aAa/aCa	6,98	1	0	benign	0,01	neutral	0,45	neutral	1,44	neutral	-2,66	deleterious	-3,57	medium_impact	2,64	neutral	0,62	neutral	0,67	deleterious	0,42	6,8	0,43	0,55	NA	NA	disease	0,66	neutral	0,4	neutral	0,16	7	neutral	0,54	deleterious	0,72	neutral	-3	neutral	0,18	medium_impact	1,14	medium_impact	0,16	medium_impact	1,37	0,51	0,8	67,4	17,16	P	0,58	P	0,88	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7732	7732	A	T	MI.5494	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	147	49	K	N	aaA/aaT	3,75	0,99	0	benign	0,22	neutral	0,33	neutral	1,44	neutral	-2,28	deleterious	-2,71	medium_impact	2,2	neutral	0,64	neutral	0,67	deleterious	0,86	9,8	0,85	0,9	NA	NA	disease	0,65	neutral	0,42	neutral	0,16	7	neutral	0,6	deleterious	0,56	neutral	-3	neutral	0,37	medium_impact	-0,21	medium_impact	0,04	medium_impact	0,96	0,68	0,85	67,4	17,16	N	0,49	N	0,84	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7732	7732	A	C	MI.5495	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	147	49	K	N	aaA/aaC	3,75	0,99	0	benign	0,22	neutral	0,33	neutral	1,44	neutral	-2,28	deleterious	-2,71	medium_impact	2,2	neutral	0,64	neutral	0,67	deleterious	0,81	9,5	0,85	0,9	NA	NA	disease	0,65	neutral	0,42	neutral	0,16	7	neutral	0,6	deleterious	0,56	neutral	-3	neutral	0,37	medium_impact	-0,21	medium_impact	0,04	medium_impact	0,96	0,68	0,85	67,4	17,16	N	0,49	N	0,84	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7733	7733	C	A	MI.5496	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	148	50	L	M	Cta/Ata	0,06	0	0	benign	0,38	deleterious	0,04	neutral	1,37	neutral	-2,27	neutral	-1,59	medium_impact	2,51	damaging	0,6	neutral	0,49	deleterious	3,39	23	0,53	0,6	NA	NA	neutral	0,34	neutral	0,28	neutral	0,19	6	neutral	0,95	neutral	0,33	deleterious	1	neutral	0,29	medium_impact	-0,52	medium_impact	-0,56	medium_impact	1,25	0,78	0,85	68,72	18,99	N	0,48	N	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7733	7733	C	G	MI.5497	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	148	50	L	V	Cta/Gta	0,06	0	0	benign	0,38	neutral	0,24	neutral	1,47	neutral	-0,8	neutral	-2,49	medium_impact	2,25	damaging	0,51	neutral	0,49	deleterious	2,87	21,7	0,47	0,55	NA	NA	neutral	0,31	neutral	0,43	neutral	0,17	7	neutral	0,72	neutral	0,43	neutral	-3	neutral	0,35	medium_impact	-0,52	medium_impact	-0,07	medium_impact	1	0,7	0,85	68,72	18,99	N	0,46	N	0,66	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7734	7734	T	G	MI.5498	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	149	50	L	R	cTa/cGa	-0,86	0	0	probably_damaging	0,99	neutral	0,1	neutral	1,34	deleterious	-3,12	deleterious	-5,43	medium_impact	2,28	damaging	0,37	damaging	0,26	deleterious	4,09	23,7	0,47	0,55	NA	NA	disease	0,81	disease	0,53	disease	0,64	3	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,85	low_impact	-2,58	medium_impact	-0,32	medium_impact	1,03	0,49	0,8	68,72	18,99	N	0,49	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7734	7734	T	A	MI.5499	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	149	50	L	Q	cTa/cAa	-0,86	0	0	probably_damaging	0,99	neutral	0,12	neutral	1,39	neutral	-1,8	deleterious	-5,37	medium_impact	2,56	damaging	0,57	neutral	0,32	deleterious	4,08	23,7	0,42	0,55	NA	NA	disease	0,63	neutral	0,31	neutral	0,18	6	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,78	low_impact	-2,58	medium_impact	-0,27	medium_impact	1,3	0,61	0,8	68,72	18,99	N	0,35	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8551	8551	T	A	MI.55	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	25	9	F	I	Ttc/Atc	0,59	0,99	0	probably_damaging	0,95	deleterious	0,01	neutral	3,88	neutral	-1,47	deleterious	-5,27	medium_impact	3,24	neutral	0,66	neutral	0,69	deleterious	4,17	23,8	0,29	0,65	disease	0,66	disease	0,82	disease	0,81	disease	0,81	6	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,8	low_impact	-1,97	medium_impact	-0,84	medium_impact	1,68	0,46	0,9	49,56	8,77	N	0,49	N	0,95	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8783	8783	G	C	MI.550	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	257	86	G	A	gGa/gCa	7,07	1	0	probably_damaging	1	deleterious	0	neutral	3,71	deleterious	-4,2	deleterious	-5,47	high_impact	4,03	neutral	0,66	damaging	0,11	deleterious	3,05	22,4	0,35	0,65	disease	0,84	disease	0,62	disease	0,72	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,6	low_impact	-1,4	high_impact	2,36	0,75	0,9	50,44	8,61	N	0,51	P	0,79	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7734	7734	T	C	MI.5500	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	149	50	L	P	cTa/cCa	-0,86	0	0	probably_damaging	1	neutral	0,06	neutral	1,32	deleterious	-3,89	deleterious	-6,33	medium_impact	2,28	damaging	0,35	damaging	0,28	deleterious	3,87	23,5	0,51	0,6	NA	NA	disease	0,83	disease	0,54	disease	0,69	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,87	low_impact	-3,52	medium_impact	-0,46	medium_impact	1,03	0,52	0,8	68,72	18,99	N	0,5	N	0,99	polymorphism	0,93	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7736	7736	A	G	MI.5501	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	151	51	T	A	Act/Gct	-2,24	0	0	benign	0,28	neutral	0,4	neutral	1,53	neutral	0,15	deleterious	-3,58	medium_impact	2,02	damaging	0,52	neutral	0,52	neutral	1,72	14,51	0,76	0,8	NA	NA	neutral	0,35	neutral	0,44	neutral	0,17	7	neutral	0,52	deleterious	0,56	neutral	-3	deleterious	0,46	medium_impact	-0,34	medium_impact	0,11	medium_impact	0,79	0,33	0,8	67,4	17,12	N	0,41	N	0,65	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7736	7736	A	C	MI.5502	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	151	51	T	P	Act/Cct	-2,24	0	0	probably_damaging	0,95	neutral	0,16	neutral	1,47	neutral	-1,25	deleterious	-4,71	medium_impact	2,39	damaging	0,42	neutral	0,3	deleterious	3,33	22,9	0,52	0,6	NA	NA	disease	0,79	neutral	0,43	neutral	0,43	1	neutral	0,97	neutral	0,11	deleterious	1	deleterious	0,82	low_impact	-1,91	medium_impact	-0,19	medium_impact	1,14	0,52	0,8	67,4	17,12	N	0,42	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7736	7736	A	T	MI.5503	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	151	51	T	S	Act/Tct	-2,24	0	0	possibly_damaging	0,5	neutral	0,58	neutral	1,53	neutral	0,21	neutral	-2,45	low_impact	1,76	neutral	0,66	neutral	0,75	neutral	1,57	13,68	0,74	0,75	NA	NA	neutral	0,34	neutral	0,25	neutral	0,19	6	neutral	0,45	deleterious	0,54	neutral	-3	deleterious	0,52	medium_impact	-0,72	medium_impact	0,28	medium_impact	0,55	0,54	0,8	67,4	17,12	N	0,31	N	0,8	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7737	7737	C	T	MI.5504	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	152	51	T	I	aCt/aTt	4,44	0,9	0	benign	0,35	neutral	0,47	neutral	1,49	neutral	-1,45	deleterious	-4,43	neutral_impact	0,72	neutral	0,75	neutral	0,84	neutral	0,96	10,41	0,79	0,8	NA	NA	neutral	0,23	neutral	0,28	neutral	0,19	6	neutral	0,45	deleterious	0,56	neutral	-6	neutral	0,3	medium_impact	-0,47	medium_impact	0,18	medium_impact	-0,43	0,46	0,8	67,4	17,12	N	0,43	N	0,77	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7737	7737	C	G	MI.5505	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	152	51	T	S	aCt/aGt	4,44	0,9	0	possibly_damaging	0,5	neutral	0,58	neutral	1,53	neutral	0,21	neutral	-2,45	low_impact	1,76	neutral	0,66	neutral	0,75	neutral	1,7	14,42	0,74	0,75	NA	NA	neutral	0,34	neutral	0,25	neutral	0,19	6	neutral	0,45	deleterious	0,54	neutral	-3	deleterious	0,52	medium_impact	-0,72	medium_impact	0,28	medium_impact	0,55	0,54	0,8	67,4	17,12	N	0,36	N	0,8	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7737	7737	C	A	MI.5506	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	152	51	T	N	aCt/aAt	4,44	0,9	0	probably_damaging	0,92	neutral	0,3	neutral	1,44	neutral	-0,13	deleterious	-3,67	medium_impact	1,94	damaging	0,51	neutral	0,41	deleterious	3,54	23,1	0,9	0,95	NA	NA	disease	0,6	neutral	0,3	neutral	0,19	6	neutral	0,93	neutral	0,19	deleterious	1	deleterious	0,75	low_impact	-1,71	medium_impact	0	medium_impact	0,71	0,64	0,8	67,4	17,12	N	0,45	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7739	7739	A	T	MI.5507	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	154	52	N	Y	Aat/Tat	-11,47	0	0	possibly_damaging	0,9	neutral	1	neutral	1,43	neutral	-2,07	deleterious	-2,85	low_impact	1,65	neutral	0,7	neutral	0,75	deleterious	2,43	19,05	0,66	0,7	NA	NA	disease	0,72	neutral	0,46	neutral	0,5	0	neutral	0,89	deleterious	0,55	neutral	-3	deleterious	0,76	low_impact	-1,61	high_impact	1,86	medium_impact	0,44	0,43	0,8	27,75	67,09	N	0,24	N	0,44	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7739	7739	A	G	MI.5508	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	154	52	N	D	Aat/Gat	-11,47	0	0	benign	0,34	neutral	0,2	neutral	1,5	neutral	-0,85	neutral	-1,92	neutral_impact	0,52	neutral	0,72	neutral	0,81	deleterious	0,61	8,23	0,92	0,95	NA	NA	neutral	0,4	neutral	0,36	neutral	0,17	7	neutral	0,76	neutral	0,43	neutral	-6	neutral	0,39	medium_impact	-0,45	medium_impact	-0,13	medium_impact	-0,62	0,52	0,8	27,75	67,09	N	0,45	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7739	7739	A	C	MI.5509	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	154	52	N	H	Aat/Cat	-11,47	0	0	possibly_damaging	0,9	neutral	0,58	neutral	1,48	neutral	-1,1	neutral	0,1	neutral_impact	0,47	neutral	0,74	neutral	0,93	neutral	1,29	12,21	0,89	0,9	NA	NA	neutral	0,44	neutral	0,39	neutral	0,2	6	neutral	0,88	neutral	0,34	neutral	-3	deleterious	0,7	low_impact	-1,61	medium_impact	0,28	medium_impact	-0,67	0,44	0,8	27,75	67,09	N	0,33	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8785	8785	C	A	MI.551	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	259	87	L	I	Ctc/Atc	-14,45	0	0	probably_damaging	0,99	deleterious	0,02	neutral	3,88	neutral	-2,93	neutral	-1,79	medium_impact	3,17	damaging	0,56	neutral	0,56	deleterious	4,01	23,6	0,41	0,65	disease	0,56	neutral	0,42	disease	0,58	disease	0,56	1	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,73	low_impact	-2,65	medium_impact	-0,66	medium_impact	1,62	0,71	0,9	14,6	18,39	N	0,42	N	0,87	polymorphism	0,56	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7740	7740	A	G	MI.5510	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	155	52	N	S	aAt/aGt	0,29	0,05	0	benign	0,04	neutral	0,45	neutral	1,47	neutral	-1,17	neutral	-2,48	low_impact	1,26	neutral	0,8	neutral	0,94	deleterious	-0,03	2,3	0,85	0,85	NA	NA	disease	0,59	neutral	0,39	neutral	0,45	1	neutral	0,51	deleterious	0,71	neutral	-6	neutral	0,19	medium_impact	0,57	medium_impact	0,16	medium_impact	0,08	0,23	0,8	27,75	67,09	N	0,33	N	0,11	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7740	7740	A	C	MI.5511	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	155	52	N	T	aAt/aCt	0,29	0,05	0	benign	0,34	neutral	0,38	neutral	1,46	neutral	-1,3	deleterious	-3,54	medium_impact	2,28	damaging	0,56	neutral	0,61	neutral	1,67	14,25	0,8	0,85	NA	NA	disease	0,66	neutral	0,38	neutral	0,47	1	neutral	0,55	deleterious	0,52	neutral	-3	neutral	0,35	medium_impact	-0,45	medium_impact	0,09	medium_impact	1,03	0,4	0,8	27,75	67,09	N	0,39	N	0,54	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7740	7740	A	T	MI.5512	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	155	52	N	I	aAt/aTt	0,29	0,05	0	possibly_damaging	0,86	neutral	0,39	neutral	1,4	deleterious	-3,12	deleterious	-5,38	medium_impact	2,93	damaging	0,54	neutral	0,61	deleterious	3,72	23,3	0,65	0,7	NA	NA	disease	0,79	disease	0,61	disease	0,67	3	neutral	0,86	neutral	0,27	NA	0	deleterious	0,7	low_impact	-1,46	medium_impact	0,1	medium_impact	1,64	0,32	0,8	27,75	67,09	N	0,35	N	0,88	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7741	7741	T	A	MI.5513	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	156	52	N	K	aaT/aaA	4,21	0,43	0	possibly_damaging	0,46	neutral	0,29	neutral	1,53	neutral	-0,45	deleterious	-3,27	medium_impact	2,79	damaging	0,5	neutral	0,51	deleterious	2,56	19,84	0,89	0,9	NA	NA	disease	0,77	disease	0,64	disease	0,67	3	neutral	0,67	neutral	0,42	NA	0	deleterious	0,49	medium_impact	-0,66	medium_impact	-0,01	medium_impact	1,51	0,46	0,8	27,75	67,09	N	0,42	N	0,65	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7741	7741	T	G	MI.5514	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	156	52	N	K	aaT/aaG	4,21	0,43	0	possibly_damaging	0,46	neutral	0,29	neutral	1,53	neutral	-0,45	deleterious	-3,27	medium_impact	2,79	damaging	0,5	neutral	0,51	deleterious	2,26	17,93	0,89	0,9	NA	NA	disease	0,77	disease	0,64	disease	0,67	3	neutral	0,67	neutral	0,42	NA	0	deleterious	0,49	medium_impact	-0,66	medium_impact	-0,01	medium_impact	1,51	0,46	0,8	27,75	67,09	N	0,4	N	0,65	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7742	7742	A	T	MI.5515	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	157	53	T	S	Act/Tct	-5,7	0	0	probably_damaging	0,99	neutral	0,45	neutral	1,63	neutral	0,57	neutral	-2,12	low_impact	0,9	neutral	0,71	neutral	0,58	neutral	1,2	11,72	0,75	0,8	NA	NA	neutral	0,37	disease	0,55	neutral	0,31	4	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,75	low_impact	-2,58	medium_impact	0,16	medium_impact	-0,26	0,59	0,8	66,52	19,11	N	0,28	N	0,8	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7742	7742	A	G	MI.5516	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	157	53	T	A	Act/Gct	-5,7	0	0	probably_damaging	0,99	neutral	0,53	neutral	1,58	neutral	-0,03	deleterious	-3	low_impact	1,42	neutral	0,62	neutral	0,38	deleterious	0,16	4,28	0,68	0,7	NA	NA	neutral	0,28	disease	0,59	neutral	0,35	3	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,72	low_impact	-2,58	medium_impact	0,23	medium_impact	0,23	0,28	0,8	66,52	19,11	N	0,25	N	0,65	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7742	7742	A	C	MI.5517	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	157	53	T	P	Act/Cct	-5,7	0	0	probably_damaging	1	neutral	0,22	neutral	1,52	neutral	-1,78	deleterious	-3,82	low_impact	1,07	damaging	0,41	damaging	0,13	deleterious	2,05	16,53	0,41	0,5	NA	NA	disease	0,78	disease	0,56	disease	0,69	4	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,83	low_impact	-3,52	medium_impact	-0,1	medium_impact	-0,1	0,57	0,8	66,52	19,11	N	0,41	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7743	7743	C	T	MI.5518	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	158	53	T	I	aCt/aTt	4,67	1	0	probably_damaging	1	neutral	0,43	neutral	1,52	neutral	-1,69	deleterious	-3,89	low_impact	1,36	damaging	0,52	damaging	0,17	deleterious	0,7	8,84	0,51	0,6	NA	NA	neutral	0,48	disease	0,57	neutral	0,49	0	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,79	low_impact	-3,52	medium_impact	0,14	medium_impact	0,17	0,45	0,8	66,52	19,11	N	0,47	N	0,77	disease_causing	0,8	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7743	7743	C	A	MI.5519	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	158	53	T	N	aCt/aAt	4,67	1	0	probably_damaging	1	neutral	0,37	neutral	1,56	neutral	-0,45	deleterious	-2,71	low_impact	1,32	damaging	0,56	damaging	0,26	deleterious	2,19	17,47	0,7	0,75	NA	NA	disease	0,62	neutral	0,46	neutral	0,38	2	deleterious	1	neutral	0,19	neutral	-2	deleterious	0,78	low_impact	-3,52	medium_impact	0,08	medium_impact	0,13	0,56	0,8	66,52	19,11	N	0,43	N	0,87	disease_causing	0,79	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8785	8785	C	T	MI.552	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	259	87	L	F	Ctc/Ttc	-14,45	0	0	probably_damaging	1	deleterious	0	neutral	3,83	deleterious	-3,93	deleterious	-3,59	high_impact	3,94	damaging	0,35	neutral	0,43	deleterious	3,95	23,6	0,41	0,65	disease	0,74	disease	0,6	disease	0,69	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,79	low_impact	-3,6	low_impact	-1,4	high_impact	2,28	0,66	0,9	14,6	18,39	P	0,54	P	0,97	disease_causing	0,88	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7743	7743	C	G	MI.5520	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	158	53	T	S	aCt/aGt	4,67	1	0	probably_damaging	0,99	neutral	0,45	neutral	1,63	neutral	0,57	neutral	-2,12	low_impact	0,9	neutral	0,71	neutral	0,58	neutral	1,56	13,63	0,75	0,8	NA	NA	neutral	0,37	disease	0,55	neutral	0,31	4	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,75	low_impact	-2,58	medium_impact	0,16	medium_impact	-0,26	0,59	0,8	66,52	19,11	N	0,45	N	0,8	polymorphism	0,73	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7745	7745	A	C	MI.5521	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	160	54	N	H	Aac/Cac	-5,7	0	0	possibly_damaging	0,72	neutral	0,48	neutral	1,53	neutral	-1,23	neutral	-1,27	low_impact	1,02	neutral	0,79	neutral	0,74	deleterious	0,8	9,49	0,73	0,75	NA	NA	neutral	0,24	neutral	0,32	neutral	0,15	7	neutral	0,71	neutral	0,38	neutral	-3	deleterious	0,54	low_impact	-1,1	medium_impact	0,19	medium_impact	-0,15	0,37	0,8	29,52	35,15	N	0,3	N	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7745	7745	A	G	MI.5522	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	160	54	N	D	Aac/Gac	-5,7	0	0	benign	0,14	neutral	0,23	neutral	1,55	neutral	-0,9	neutral	-1,86	medium_impact	2,02	neutral	0,68	neutral	0,48	deleterious	0,62	8,27	0,85	0,9	NA	NA	neutral	0,34	neutral	0,45	neutral	0,15	7	neutral	0,73	deleterious	0,55	neutral	-3	neutral	0,19	medium_impact	0,01	medium_impact	-0,09	medium_impact	0,79	0,53	0,8	29,52	35,15	N	0,43	N	0,19	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7745	7745	A	T	MI.5523	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	160	54	N	Y	Aac/Tac	-5,7	0	0	possibly_damaging	0,72	neutral	1	neutral	1,7	neutral	-1,31	neutral	-2,29	neutral_impact	-0,04	neutral	0,74	neutral	0,86	deleterious	0,56	7,88	0,47	0,55	NA	NA	neutral	0,17	neutral	0,26	neutral	0,17	7	neutral	0,72	deleterious	0,64	neutral	-3	deleterious	0,54	low_impact	-1,1	high_impact	1,86	low_impact	-1,14	0,37	0,8	29,52	35,15	N	0,24	N	0,32	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7746	7746	A	C	MI.5524	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	161	54	N	T	aAc/aCc	2,6	0,02	0	benign	0,14	neutral	0,43	neutral	1,59	neutral	-0,68	neutral	-1,85	low_impact	1,24	neutral	0,79	neutral	0,83	neutral	-0,17	1,28	0,61	0,65	NA	NA	neutral	0,27	neutral	0,26	neutral	0,18	6	neutral	0,49	deleterious	0,65	neutral	-6	neutral	0,16	medium_impact	0,01	medium_impact	0,14	medium_impact	0,06	0,32	0,8	29,52	35,15	N	0,4	N	0,14	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7746	7746	A	T	MI.5525	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	161	54	N	I	aAc/aTc	2,6	0,02	0	possibly_damaging	0,66	neutral	0,47	neutral	1,57	neutral	-2,64	deleterious	-3,53	medium_impact	2,11	neutral	0,68	neutral	0,55	deleterious	0,59	8,11	0,46	0,55	NA	NA	neutral	0,4	neutral	0,43	neutral	0,15	7	neutral	0,64	neutral	0,41	NA	0	deleterious	0,48	medium_impact	-0,99	medium_impact	0,18	medium_impact	0,87	0,29	0,8	29,52	35,15	N	0,4	N	0,38	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7746	7746	A	G	MI.5526	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	161	54	N	S	aAc/aGc	2,6	0,02	0	benign	0,01	neutral	0,44	neutral	1,59	neutral	-0,49	neutral	-0,95	neutral_impact	0,16	neutral	0,87	neutral	0,99	neutral	-0,67	0,08	0,74	0,75	NA	NA	neutral	0,23	neutral	0,3	neutral	0,17	7	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,11	medium_impact	1,14	medium_impact	0,15	medium_impact	-0,96	0,14	0,8	29,52	35,15	N	0,43	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7747	7747	C	A	MI.5527	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	162	54	N	K	aaC/aaA	-0,4	0	0	benign	0,2	neutral	0,32	neutral	1,62	neutral	-0,11	neutral	-2,27	neutral_impact	0,7	neutral	0,7	neutral	0,47	neutral	1,01	10,73	0,79	0,8	NA	NA	neutral	0,39	neutral	0,48	neutral	0,15	7	neutral	0,62	deleterious	0,56	neutral	-6	neutral	0,26	medium_impact	-0,16	medium_impact	0,02	medium_impact	-0,45	0,43	0,8	29,52	35,15	N	0,36	N	0,23	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7747	7747	C	G	MI.5528	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	162	54	N	K	aaC/aaG	-0,4	0	0	benign	0,2	neutral	0,32	neutral	1,62	neutral	-0,11	neutral	-2,27	neutral_impact	0,7	neutral	0,7	neutral	0,47	deleterious	0,48	7,31	0,79	0,8	NA	NA	neutral	0,39	neutral	0,48	neutral	0,15	7	neutral	0,62	deleterious	0,56	neutral	-6	neutral	0,26	medium_impact	-0,16	medium_impact	0,02	medium_impact	-0,45	0,43	0,8	29,52	35,15	N	0,36	N	0,23	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7748	7748	A	G	MI.5529	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	163	55	I	V	Atc/Gtc	-2,01	0	0	probably_damaging	0,97	neutral	0,38	neutral	1,55	neutral	-0,04	neutral	0,51	neutral_impact	0,05	neutral	0,78	neutral	0,86	neutral	-0,39	0,42	0,69	0,75	NA	NA	neutral	0,13	neutral	0,36	neutral	0,23	5	neutral	0,97	neutral	0,21	neutral	-2	deleterious	0,62	low_impact	-2,13	medium_impact	0,09	low_impact	-1,06	0,44	0,8	28,63	65,2	N	0,38	N	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8785	8785	C	G	MI.553	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	259	87	L	V	Ctc/Gtc	-14,45	0	0	probably_damaging	0,99	deleterious	0,01	neutral	3,92	neutral	-2,38	deleterious	-2,66	high_impact	3,94	damaging	0,36	neutral	0,42	deleterious	3,35	22,9	0,47	0,65	disease	0,59	neutral	0,45	disease	0,68	disease	0,58	2	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,75	low_impact	-2,65	medium_impact	-0,84	high_impact	2,28	0,74	0,9	14,6	18,39	P	0,56	P	0,87	disease_causing	0,58	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7748	7748	A	C	MI.5530	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	163	55	I	L	Atc/Ctc	-2,01	0	0	probably_damaging	0,97	neutral	1	neutral	1,7	neutral	-0,5	neutral	-0,26	neutral_impact	-0,2	neutral	0,68	neutral	0,64	neutral	-0,65	0,1	0,55	0,6	NA	NA	neutral	0,09	neutral	0,21	neutral	0,21	6	neutral	0,97	deleterious	0,52	neutral	-2	deleterious	0,61	low_impact	-2,13	high_impact	1,86	low_impact	-1,29	0,63	0,8	28,63	65,2	N	0,29	N	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7748	7748	A	T	MI.5531	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	163	55	I	F	Atc/Ttc	-2,01	0	0	probably_damaging	0,99	neutral	0,33	neutral	1,58	neutral	-0,04	neutral	-1,62	neutral_impact	0,36	damaging	0,58	neutral	0,43	deleterious	2,02	16,32	0,49	0,55	NA	NA	neutral	0,47	neutral	0,34	neutral	0,23	5	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,71	low_impact	-2,58	medium_impact	0,04	medium_impact	-0,77	0,67	0,85	28,63	65,2	N	0,36	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7749	7749	T	A	MI.5532	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	164	55	I	N	aTc/aAc	4,44	0,94	0	probably_damaging	1	neutral	0,1	neutral	1,46	deleterious	-3,25	neutral	-1,15	low_impact	1,5	damaging	0,6	neutral	0,45	deleterious	2,64	20,4	0,46	0,55	NA	NA	disease	0,65	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,76	low_impact	-3,52	medium_impact	-0,32	medium_impact	0,3	0,59	0,8	28,63	65,2	N	0,44	N	0,58	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7749	7749	T	G	MI.5533	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	164	55	I	S	aTc/aGc	4,44	0,94	0	probably_damaging	0,99	neutral	0,34	neutral	1,49	neutral	-1,96	neutral	0,07	low_impact	1,21	neutral	0,67	neutral	0,64	neutral	1,16	11,52	0,4	0,5	NA	NA	disease	0,59	neutral	0,4	neutral	0,33	3	deleterious	0,99	neutral	0,18	neutral	-2	deleterious	0,74	low_impact	-2,58	medium_impact	0,05	medium_impact	0,03	0,63	0,8	28,63	65,2	N	0,44	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7749	7749	T	C	MI.5534	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	164	55	I	T	aTc/aCc	4,44	0,94	0	probably_damaging	0,99	neutral	0,24	neutral	1,52	neutral	-0,8	neutral	2,38	neutral_impact	-0,26	neutral	0,78	neutral	0,91	neutral	-1,36	0	0,58	0,65	NA	NA	neutral	0,24	neutral	0,35	neutral	0,14	7	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,69	low_impact	-2,58	medium_impact	-0,07	low_impact	-1,35	0,65	0,8	28,63	65,2	N	0,43	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7750	7750	C	G	MI.5535	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	165	55	I	M	atC/atG	2,14	0,91	0	probably_damaging	1	neutral	0,25	neutral	1,5	neutral	-1,91	neutral	-0,29	neutral_impact	0,22	neutral	0,67	neutral	0,61	deleterious	1,93	15,77	0,62	0,65	NA	NA	neutral	0,22	neutral	0,27	neutral	0,16	7	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,68	low_impact	-3,52	medium_impact	-0,06	medium_impact	-0,9	0,7	0,85	28,63	65,2	N	0,43	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7750	7750	C	A	MI.5536	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	165	55	I	M	atC/atA	2,14	0,91	0	probably_damaging	1	neutral	0,25	neutral	1,5	neutral	-1,91	neutral	-0,29	neutral_impact	0,22	neutral	0,67	neutral	0,61	deleterious	2,35	18,47	0,62	0,65	NA	NA	neutral	0,22	neutral	0,27	neutral	0,16	7	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,68	low_impact	-3,52	medium_impact	-0,06	medium_impact	-0,9	0,7	0,85	28,63	65,2	N	0,43	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7751	7751	T	G	MI.5537	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	166	56	S	A	Tca/Gca	-12,16	0	0	benign	0,03	neutral	0,49	neutral	1,61	neutral	-0,63	neutral	0,37	low_impact	1,21	neutral	0,77	neutral	0,71	neutral	1,65	14,15	0,63	0,7	NA	NA	neutral	0,16	disease	0,54	neutral	0,22	6	neutral	0,48	deleterious	0,73	neutral	-6	neutral	0,13	medium_impact	0,69	medium_impact	0,2	medium_impact	0,03	0,54	0,8	29,52	67,06	N	0,37	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7751	7751	T	C	MI.5538	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	166	56	S	P	Tca/Cca	-12,16	0	0	benign	0,2	neutral	0,18	neutral	1,54	neutral	-1,32	neutral	-1,2	medium_impact	2,02	neutral	0,69	neutral	0,38	deleterious	2,12	16,96	0,41	0,5	NA	NA	disease	0,66	disease	0,53	disease	0,58	2	neutral	0,79	deleterious	0,49	neutral	-3	neutral	0,32	medium_impact	-0,16	medium_impact	-0,16	medium_impact	0,79	0,5	0,8	29,52	67,06	N	0,35	N	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7751	7751	T	A	MI.5539	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	166	56	S	T	Tca/Aca	-12,16	0	0	benign	0	neutral	0,48	neutral	1,65	neutral	-0,71	neutral	0,81	neutral_impact	-0,42	neutral	0,92	neutral	0,84	deleterious	0,38	6,43	0,48	0,55	NA	NA	neutral	0,16	neutral	0,27	neutral	0,22	6	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,11	high_impact	2,08	medium_impact	0,19	low_impact	-1,5	0,59	0,8	29,52	67,06	N	0,41	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8786	8786	T	A	MI.554	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	260	87	L	H	cTc/cAc	0,13	0	0	probably_damaging	1	deleterious	0	neutral	3,8	deleterious	-5,48	deleterious	-6,31	high_impact	4,49	damaging	0,43	neutral	0,37	deleterious	4,26	23,9	0,22	0,65	disease	0,92	disease	0,75	disease	0,76	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,6	low_impact	-1,4	high_impact	2,75	0,61	0,9	14,6	18,39	P	0,6	P	0,97	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7752	7752	C	G	MI.5540	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	167	56	S	W	tCa/tGa	0,52	0,06	0	possibly_damaging	0,74	neutral	0,24	neutral	1,53	deleterious	-5,48	neutral	-0,84	medium_impact	2,02	neutral	0,62	neutral	0,44	deleterious	4,07	23,7	0,27	0,45	NA	NA	disease	0,59	disease	0,63	disease	0,65	3	neutral	0,83	neutral	0,25	NA	0	deleterious	0,64	low_impact	-1,14	medium_impact	-0,07	medium_impact	0,79	0,51	0,8	29,52	67,06	N	0,41	N	0,57	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7752	7752	C	T	MI.5541	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	167	56	S	L	tCa/tTa	0,52	0,06	0	benign	0,07	neutral	1	neutral	1,81	neutral	-2,21	neutral	2,97	neutral_impact	-1,88	neutral	0,7	neutral	0,81	deleterious	-0,02	2,39	0,52	0,6	NA	NA	neutral	0,09	neutral	0,27	neutral	0,18	6	neutral	0,07	deleterious	0,97	neutral	-6	neutral	0,1	medium_impact	0,33	high_impact	1,86	low_impact	-2,87	0,84	0,9	29,52	67,06	N	0,29	N	0,3	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7754	7754	G	A	MI.5542	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	169	57	D	N	Gac/Aac	0,29	0,96	0	benign	0,01	neutral	0,45	neutral	1,53	neutral	-0,67	deleterious	-3,56	low_impact	1,43	neutral	0,71	neutral	0,71	neutral	1,03	10,85	0,85	0,9	NA	NA	disease	0,54	neutral	0,41	neutral	0,17	7	neutral	0,54	deleterious	0,72	neutral	-6	neutral	0,16	medium_impact	1,14	medium_impact	0,16	medium_impact	0,24	0,65	0,8	71,81	14,32	N	0,39	N	0,99	polymorphism	0,66	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7754	7754	G	T	MI.5543	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	169	57	D	Y	Gac/Tac	0,29	0,96	0	probably_damaging	0,91	neutral	0,05	neutral	1,44	deleterious	-3,26	deleterious	-7,82	medium_impact	3,21	damaging	0,48	damaging	0,25	deleterious	3,75	23,3	0,33	0,5	NA	NA	disease	0,78	disease	0,67	disease	0,71	4	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,76	low_impact	-1,66	medium_impact	-0,5	medium_impact	1,9	0,23	0,8	71,81	14,32	N	0,42	N	0,99	disease_causing	0,85	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7754	7754	G	C	MI.5544	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	169	57	D	H	Gac/Cac	0,29	0,96	0	possibly_damaging	0,69	neutral	0,12	neutral	1,63	neutral	0,4	deleterious	-5,83	low_impact	0,96	damaging	0,55	damaging	0,22	deleterious	2,2	17,52	0,6	0,65	NA	NA	neutral	0,4	neutral	0,5	neutral	0,15	7	neutral	0,9	neutral	0,22	neutral	-3	deleterious	0,58	low_impact	-1,04	medium_impact	-0,27	medium_impact	-0,21	0,63	0,8	71,81	14,32	N	0,38	N	0,98	disease_causing	0,73	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7755	7755	A	C	MI.5545	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	170	57	D	A	gAc/gCc	3,52	1	0	benign	0,16	neutral	0,66	neutral	1,48	neutral	-1,45	deleterious	-6,96	medium_impact	2,66	neutral	0,64	neutral	0,39	neutral	1,68	14,3	0,34	0,5	NA	NA	disease	0,58	disease	0,64	disease	0,67	3	neutral	0,22	deleterious	0,75	neutral	-3	neutral	0,37	medium_impact	-0,05	medium_impact	0,36	medium_impact	1,39	0,36	0,8	71,81	14,32	N	0,4	N	0,96	disease_causing	0,98	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7755	7755	A	G	MI.5546	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	170	57	D	G	gAc/gGc	3,52	1	0	benign	0,21	neutral	0,32	neutral	1,6	neutral	0,16	deleterious	-6,01	medium_impact	2,58	damaging	0,57	neutral	0,36	deleterious	2,1	16,83	0,41	0,5	NA	NA	disease	0,7	disease	0,64	disease	0,68	4	neutral	0,62	deleterious	0,56	neutral	-3	neutral	0,27	medium_impact	-0,18	medium_impact	0,02	medium_impact	1,31	0,36	0,8	71,81	14,32	N	0,43	N	0,97	disease_causing	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7755	7755	A	T	MI.5547	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	170	57	D	V	gAc/gTc	3,52	1	0	possibly_damaging	0,61	neutral	0,25	neutral	1,44	deleterious	-3,64	deleterious	-7,92	medium_impact	2,87	damaging	0,51	damaging	0,26	deleterious	3,27	22,8	0,3	0,45	NA	NA	disease	0,68	disease	0,63	disease	0,69	4	neutral	0,76	neutral	0,32	NA	0	deleterious	0,59	medium_impact	-0,9	medium_impact	-0,06	medium_impact	1,59	0,29	0,8	71,81	14,32	N	0,44	N	0,99	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7756	7756	C	A	MI.5548	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	171	57	D	E	gaC/gaA	8,59	1	0	benign	0,04	neutral	1	neutral	1,71	neutral	0,89	deleterious	-3,31	neutral_impact	0,34	damaging	0,55	neutral	0,33	deleterious	0,86	9,81	0,72	0,75	NA	NA	neutral	0,16	neutral	0,26	neutral	0,16	7	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,13	medium_impact	0,57	high_impact	1,86	medium_impact	-0,79	0,54	0,8	71,81	14,32	P	0,51	P	0,95	disease_causing	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7756	7756	C	G	MI.5549	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	171	57	D	E	gaC/gaG	8,59	1	0	benign	0,04	neutral	1	neutral	1,71	neutral	0,89	deleterious	-3,31	neutral_impact	0,34	damaging	0,55	neutral	0,33	deleterious	0,51	7,53	0,72	0,75	NA	NA	neutral	0,16	neutral	0,26	neutral	0,16	7	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,13	medium_impact	0,57	high_impact	1,86	medium_impact	-0,79	0,54	0,8	71,81	14,32	P	0,52	P	0,95	disease_causing	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8786	8786	T	G	MI.555	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	260	87	L	R	cTc/cGc	0,13	0	0	probably_damaging	1	deleterious	0	neutral	3,81	deleterious	-4,87	deleterious	-5,39	high_impact	4,14	damaging	0,31	neutral	0,36	deleterious	4,15	23,8	0,16	0,65	disease	0,89	disease	0,81	disease	0,79	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,45	0,59	0,9	14,6	18,39	P	0,72	P	0,99	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7757	7757	G	T	MI.5550	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	172	58	A	S	Gct/Tct	-5,47	0	0	probably_damaging	0,99	neutral	0,78	neutral	1,7	neutral	0,7	neutral	-0,98	neutral_impact	0,24	neutral	0,7	neutral	0,77	neutral	1,4	12,78	0,49	0,55	NA	NA	neutral	0,34	neutral	0,28	neutral	0,16	7	deleterious	0,99	neutral	0,4	neutral	-2	deleterious	0,76	low_impact	-2,58	medium_impact	0,51	medium_impact	-0,88	0,69	0,85	68,28	18,75	N	0,28	N	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7757	7757	G	C	MI.5551	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	172	58	A	P	Gct/Cct	-5,47	0	0	probably_damaging	1	neutral	0,26	neutral	1,54	neutral	-1,92	deleterious	-3,86	medium_impact	3,13	damaging	0,51	damaging	0,27	deleterious	3,76	23,4	0,29	0,45	NA	NA	disease	0,84	disease	0,57	disease	0,74	5	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,87	low_impact	-3,52	medium_impact	-0,05	medium_impact	1,83	0,76	0,85	68,28	18,75	N	0,38	N	0,9	polymorphism	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7757	7757	G	A	MI.5552	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	172	58	A	T	Gct/Act	-5,47	0	0	probably_damaging	0,99	neutral	0,55	neutral	1,55	neutral	-0,95	neutral	-2,43	medium_impact	2,58	neutral	0,69	neutral	0,44	deleterious	4,18	23,8	0,61	0,65	NA	NA	disease	0,51	disease	0,59	disease	0,66	3	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,77	low_impact	-2,58	medium_impact	0,25	medium_impact	1,31	0,84	0,9	68,28	18,75	N	0,26	N	0,72	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7758	7758	C	G	MI.5553	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	173	58	A	G	gCt/gGt	3,06	0,99	0	probably_damaging	0,98	neutral	0,43	neutral	1,73	neutral	-0,31	deleterious	-2,79	neutral_impact	0,2	damaging	0,58	neutral	0,52	deleterious	2,22	17,64	0,48	0,55	NA	NA	neutral	0,07	neutral	0,23	neutral	0,22	6	neutral	0,97	neutral	0,23	neutral	-2	deleterious	0,68	low_impact	-2,3	medium_impact	0,14	medium_impact	-0,92	0,71	0,85	68,28	18,75	P	0,48	N	0,74	disease_causing	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7758	7758	C	A	MI.5554	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	173	58	A	D	gCt/gAt	3,06	0,99	0	probably_damaging	1	neutral	0,59	neutral	1,58	neutral	-1,07	deleterious	-4,18	medium_impact	2,04	damaging	0,54	neutral	0,34	deleterious	4,35	24,1	0,28	0,45	NA	NA	disease	0,78	disease	0,65	disease	0,72	4	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,85	low_impact	-3,52	medium_impact	0,29	medium_impact	0,81	0,64	0,8	68,28	18,75	N	0,41	N	0,94	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7758	7758	C	T	MI.5555	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	173	58	A	V	gCt/gTt	3,06	0,99	0	probably_damaging	0,99	neutral	0,32	neutral	1,52	neutral	-1,87	deleterious	-3,5	medium_impact	2,44	neutral	0,64	neutral	0,66	deleterious	4,27	24	0,44	0,55	NA	NA	disease	0,52	neutral	0,49	neutral	0,32	4	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,79	low_impact	-2,58	medium_impact	0,02	medium_impact	1,18	0,67	0,85	68,28	18,75	P	0,53	P	0,79	disease_causing	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7760	7760	C	A	MI.5556	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	175	59	Q	K	Cag/Aag	-13,77	0	0	probably_damaging	0,91	neutral	0,25	neutral	1,37	neutral	-1,59	deleterious	-3,73	high_impact	3,58	damaging	0,3	damaging	0,22	deleterious	3,9	23,5	0,55	0,6	NA	NA	disease	0,8	disease	0,65	disease	0,65	3	neutral	0,94	neutral	0,17	deleterious	2	deleterious	0,79	low_impact	-1,66	medium_impact	-0,06	high_impact	2,25	0,59	0,8	67,84	19,24	N	0,53	P	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7760	7760	C	G	MI.5557	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	175	59	Q	E	Cag/Gag	-13,77	0	0	possibly_damaging	0,82	neutral	0,52	neutral	1,37	neutral	-1,59	deleterious	-2,73	medium_impact	3,15	damaging	0,31	neutral	0,29	deleterious	2,95	22,1	0,49	0,55	NA	NA	disease	0,73	disease	0,64	disease	0,54	1	neutral	0,8	neutral	0,35	NA	0	deleterious	0,77	low_impact	-1,33	medium_impact	0,22	medium_impact	1,85	0,57	0,8	67,84	19,24	P	0,54	P	0,85	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7761	7761	A	T	MI.5558	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	176	59	Q	L	cAg/cTg	7,21	1	0	probably_damaging	0,91	neutral	0,54	neutral	1,29	deleterious	-3,12	deleterious	-6,68	high_impact	3,69	damaging	0,32	neutral	0,35	deleterious	3,72	23,3	0,35	0,5	NA	NA	disease	0,83	disease	0,67	disease	0,67	3	neutral	0,9	neutral	0,32	deleterious	2	deleterious	0,82	low_impact	-1,66	medium_impact	0,24	high_impact	2,35	0,24	0,8	67,84	19,24	P	0,75	P	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7761	7761	A	G	MI.5559	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	176	59	Q	R	cAg/cGg	7,21	1	0	probably_damaging	0,94	neutral	0,26	neutral	1,32	neutral	-2,3	deleterious	-3,77	high_impact	3,84	damaging	0,32	damaging	0,25	deleterious	3,43	23	0,59	0,65	NA	NA	disease	0,81	disease	0,72	disease	0,68	4	neutral	0,96	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-1,83	medium_impact	-0,05	high_impact	2,5	0,5	0,8	67,84	19,24	P	0,79	P	0,95	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8786	8786	T	C	MI.556	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	260	87	L	P	cTc/cCc	0,13	0	0	probably_damaging	1	deleterious	0	neutral	3,8	deleterious	-5,55	deleterious	-6,34	high_impact	4,49	damaging	0,22	neutral	0,41	deleterious	3,89	23,5	0,18	0,65	disease	0,92	disease	0,71	disease	0,68	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,6	low_impact	-1,4	high_impact	2,75	0,72	0,9	14,6	18,39	P	0,9	P	1	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7761	7761	A	C	MI.5560	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	176	59	Q	P	cAg/cCg	7,21	1	0	probably_damaging	0,98	neutral	0,21	neutral	1,28	deleterious	-3,79	deleterious	-5,37	high_impact	3,69	damaging	0,33	damaging	0,21	deleterious	3,29	22,8	0,16	0,45	NA	NA	disease	0,85	disease	0,63	disease	0,67	3	deleterious	0,98	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-2,3	medium_impact	-0,11	high_impact	2,35	0,41	0,8	67,84	19,24	P	0,71	P	0,95	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7762	7762	G	C	MI.5561	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	177	59	Q	H	caG/caC	8,59	1	0,01	probably_damaging	0,98	neutral	0,47	neutral	1,33	neutral	-2,15	deleterious	-4,52	low_impact	1,92	damaging	0,33	damaging	0,24	deleterious	3,37	22,9	0,52	0,6	NA	NA	disease	0,69	neutral	0,49	neutral	0,15	7	deleterious	0,98	neutral	0,25	neutral	-2	deleterious	0,85	low_impact	-2,3	medium_impact	0,18	medium_impact	0,7	0,64	0,8	67,84	19,24	P	0,71	P	0,86	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7762	7762	G	T	MI.5562	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	177	59	Q	H	caG/caT	8,59	1	0,01	probably_damaging	0,98	neutral	0,47	neutral	1,33	neutral	-2,15	deleterious	-4,52	low_impact	1,92	damaging	0,33	damaging	0,24	deleterious	3,46	23	0,52	0,6	NA	NA	disease	0,69	neutral	0,49	neutral	0,15	7	deleterious	0,98	neutral	0,25	neutral	-2	deleterious	0,85	low_impact	-2,3	medium_impact	0,18	medium_impact	0,7	0,64	0,8	67,84	19,24	P	0,71	P	0,86	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7763	7763	G	C	MI.5563	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	178	60	E	Q	Gaa/Caa	3,29	1	0	probably_damaging	0,98	neutral	0,34	neutral	1,52	neutral	-0,52	neutral	-1,79	low_impact	1,9	damaging	0,56	neutral	0,46	deleterious	2,18	17,41	0,54	0,6	NA	NA	neutral	0,21	neutral	0,28	neutral	0,19	6	neutral	0,98	neutral	0,18	neutral	-2	deleterious	0,7	low_impact	-2,3	medium_impact	0,05	medium_impact	0,68	0,73	0,85	67,4	19,04	P	0,55	P	0,76	disease_causing	0,96	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7763	7763	G	A	MI.5564	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	178	60	E	K	Gaa/Aaa	3,29	1	0	probably_damaging	0,97	neutral	0,33	neutral	1,55	neutral	1,15	deleterious	-2,81	low_impact	1,8	neutral	0,63	damaging	0,28	deleterious	3,33	22,9	0,38	0,5	NA	NA	neutral	0,36	disease	0,51	neutral	0,22	6	neutral	0,98	neutral	0,18	neutral	-2	deleterious	0,74	low_impact	-2,13	medium_impact	0,04	medium_impact	0,58	0,51	0,8	67,4	19,04	P	0,53	P	0,99	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7764	7764	A	G	MI.5565	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	179	60	E	G	gAa/gGa	7,44	1	0	probably_damaging	0,99	neutral	0,36	neutral	1,51	neutral	-1,44	deleterious	-4,89	low_impact	1,66	neutral	0,61	neutral	0,59	deleterious	3,14	22,6	0,37	0,5	NA	NA	neutral	0,27	disease	0,53	neutral	0,32	4	deleterious	0,99	neutral	0,19	neutral	-2	deleterious	0,72	low_impact	-2,58	medium_impact	0,07	medium_impact	0,45	0,6	0,8	67,4	19,04	P	0,57	P	0,64	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7764	7764	A	C	MI.5566	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	179	60	E	A	gAa/gCa	7,44	1	0	probably_damaging	0,98	neutral	0,51	neutral	1,57	neutral	0,39	deleterious	-3,94	low_impact	1,58	neutral	0,65	neutral	0,73	deleterious	2,57	19,91	0,32	0,5	NA	NA	neutral	0,22	neutral	0,44	neutral	0,16	7	deleterious	0,98	neutral	0,27	neutral	-2	deleterious	0,71	low_impact	-2,3	medium_impact	0,21	medium_impact	0,38	0,59	0,8	67,4	19,04	P	0,57	P	0,66	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7764	7764	A	T	MI.5567	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	179	60	E	V	gAa/gTa	7,44	1	0	probably_damaging	0,99	neutral	0,53	neutral	1,63	neutral	-0,95	deleterious	-4,79	low_impact	1,42	neutral	0,66	neutral	0,74	deleterious	4,16	23,8	0,28	0,45	NA	NA	neutral	0,35	neutral	0,46	neutral	0,15	7	deleterious	0,98	neutral	0,27	neutral	-2	deleterious	0,74	low_impact	-2,58	medium_impact	0,23	medium_impact	0,23	0,71	0,85	67,4	19,04	P	0,5	N	0,82	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7765	7765	A	C	MI.5568	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	180	60	E	D	gaA/gaC	3,75	1	0	possibly_damaging	0,9	neutral	0,21	neutral	1,51	neutral	-0,8	neutral	-2,33	medium_impact	2,35	damaging	0,51	neutral	0,37	deleterious	3,52	23,1	0,49	0,55	NA	NA	neutral	0,25	neutral	0,41	neutral	0,16	7	neutral	0,93	neutral	0,16	NA	0	deleterious	0,66	low_impact	-1,61	medium_impact	-0,11	medium_impact	1,1	0,85	0,9	67,4	19,04	P	0,74	P	0,81	disease_causing	0,95	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7765	7765	A	T	MI.5569	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	180	60	E	D	gaA/gaT	3,75	1	0	possibly_damaging	0,9	neutral	0,21	neutral	1,51	neutral	-0,8	neutral	-2,33	medium_impact	2,35	damaging	0,51	neutral	0,37	deleterious	3,67	23,3	0,49	0,55	NA	NA	neutral	0,25	neutral	0,41	neutral	0,16	7	neutral	0,93	neutral	0,16	NA	0	deleterious	0,66	low_impact	-1,61	medium_impact	-0,11	medium_impact	1,1	0,85	0,9	67,4	19,04	P	0,73	P	0,81	disease_causing	0,95	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8788	8788	C	A	MI.557	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	262	88	L	M	Ctg/Atg	-11,9	0	0	probably_damaging	0,91	neutral	0,11	neutral	4,04	deleterious	-3,26	neutral	-1,66	medium_impact	2,53	neutral	0,94	damaging	0,21	deleterious	3,61	23,2	0,36	0,65	disease	0,69	neutral	0,33	disease	0,56	disease	0,62	2	neutral	0,97	neutral	0,1	deleterious	1	deleterious	0,69	low_impact	-1,71	medium_impact	-0,22	medium_impact	1,07	0,75	0,9	15,49	18,89	N	0,4	N	0,19	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7766	7766	A	G	MI.5570	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	181	61	M	V	Ata/Gta	1,68	1	0	probably_damaging	0,94	neutral	0,48	neutral	1,77	neutral	1,85	neutral	1,94	neutral_impact	-1,27	neutral	0,78	neutral	0,93	deleterious	0,87	9,88	0,45	0,55	NA	NA	neutral	0,3	neutral	0,31	neutral	0,13	7	neutral	0,93	neutral	0,27	neutral	-2	deleterious	0,64	low_impact	-1,83	medium_impact	0,19	low_impact	-2,3	0,84	0,9	32,6	67,92	N	0,38	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7766	7766	A	T	MI.5571	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	181	61	M	L	Ata/Tta	1,68	1	0	possibly_damaging	0,9	neutral	0,92	neutral	1,76	neutral	1,79	neutral	0,38	neutral_impact	-1,26	neutral	0,65	neutral	0,31	deleterious	2,08	16,73	0,39	0,5	NA	NA	neutral	0,28	neutral	0,32	neutral	0,12	8	neutral	0,89	deleterious	0,51	neutral	-3	deleterious	0,6	low_impact	-1,61	medium_impact	0,79	low_impact	-2,29	0,77	0,85	32,6	67,92	N	0,38	N	0,35	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7766	7766	A	C	MI.5572	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	181	61	M	L	Ata/Cta	1,68	1	0	possibly_damaging	0,9	neutral	0,92	neutral	1,76	neutral	1,79	neutral	0,38	neutral_impact	-1,26	neutral	0,65	neutral	0,31	deleterious	2,02	16,32	0,39	0,5	NA	NA	neutral	0,28	neutral	0,32	neutral	0,12	8	neutral	0,89	deleterious	0,51	neutral	-3	deleterious	0,6	low_impact	-1,61	medium_impact	0,79	low_impact	-2,29	0,77	0,85	32,6	67,92	N	0,36	N	0,35	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7767	7767	T	C	MI.5573	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	182	61	M	T	aTa/aCa	0,52	0,99	0	probably_damaging	0,97	neutral	0,42	neutral	1,56	neutral	-0,56	neutral	-1,91	low_impact	0,86	damaging	0,6	neutral	0,29	deleterious	2,96	22,1	0,28	0,45	NA	NA	neutral	0,5	disease	0,54	disease	0,55	1	neutral	0,97	neutral	0,23	neutral	-2	deleterious	0,76	low_impact	-2,13	medium_impact	0,13	medium_impact	-0,3	0,43	0,8	32,6	67,92	N	0,34	N	0,45	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7767	7767	T	A	MI.5574	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	182	61	M	K	aTa/aAa	0,52	0,99	0	probably_damaging	0,97	neutral	0,22	neutral	1,53	neutral	-1,82	deleterious	-3,75	low_impact	1,32	damaging	0,52	damaging	0,24	deleterious	4,24	23,9	0,15	0,4	NA	NA	disease	0,66	disease	0,67	disease	0,66	3	deleterious	0,98	neutral	0,13	neutral	-2	deleterious	0,81	low_impact	-2,13	medium_impact	-0,1	medium_impact	0,13	0,55	0,8	32,6	67,92	N	0,4	N	0,74	polymorphism	0,94	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7768	7768	A	C	MI.5575	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	183	61	M	I	atA/atC	7,44	1	0,04	probably_damaging	0,96	neutral	1	neutral	2,03	neutral	2,95	neutral	2,16	neutral_impact	-2,42	neutral	0,75	neutral	0,7	deleterious	0,58	7,99	0,44	0,55	NA	NA	neutral	0,08	neutral	0,23	neutral	0,2	6	neutral	0,95	deleterious	0,52	neutral	-2	deleterious	0,63	low_impact	-2,01	high_impact	1,86	low_impact	-3,37	0,9	0,95	32,6	67,92	N	0,47	N	0,01	polymorphism	0,93	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7768	7768	A	T	MI.5576	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	183	61	M	I	atA/atT	7,44	1	0,04	probably_damaging	0,96	neutral	1	neutral	2,03	neutral	2,95	neutral	2,16	neutral_impact	-2,42	neutral	0,75	neutral	0,7	deleterious	0,71	8,9	0,44	0,55	NA	NA	neutral	0,08	neutral	0,23	neutral	0,2	6	neutral	0,95	deleterious	0,52	neutral	-2	deleterious	0,63	low_impact	-2,01	high_impact	1,86	low_impact	-3,37	0,9	0,95	32,6	67,92	N	0,49	N	0,01	polymorphism	0,93	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7769	7769	G	A	MI.5577	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	184	62	E	K	Gaa/Aaa	-5,47	0	0	probably_damaging	1	neutral	0,3	neutral	-0,44	deleterious	-7,15	deleterious	-3,97	high_impact	4,65	damaging	0,28	damaging	0,17	deleterious	4,44	24,2	0,28	0,45	NA	NA	disease	0,82	disease	0,88	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0	high_impact	3,25	0,68	0,85	68,72	19,33	P	0,79	P	0,99	polymorphism	0,95	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7769	7769	G	C	MI.5578	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	184	62	E	Q	Gaa/Caa	-5,47	0	0	probably_damaging	1	neutral	0,3	neutral	-0,44	deleterious	-7,49	deleterious	-2,97	high_impact	4,65	damaging	0,27	neutral	0,4	deleterious	3,26	22,8	0,33	0,5	NA	NA	disease	0,69	disease	0,82	disease	0,67	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	0	high_impact	3,25	0,7	0,85	68,72	19,33	P	0,85	P	0,76	polymorphism	0,99	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7770	7770	A	G	MI.5579	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	185	62	E	G	gAa/gGa	7,21	1	0	probably_damaging	1	neutral	0,36	neutral	-0,44	deleterious	-7,48	deleterious	-6,95	high_impact	4,65	damaging	0,25	neutral	0,42	deleterious	3,98	23,6	0,23	0,45	NA	NA	disease	0,72	disease	0,85	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	0,07	high_impact	3,25	0,43	0,8	68,72	19,33	P	0,92	P	0,64	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8788	8788	C	G	MI.558	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	262	88	L	V	Ctg/Gtg	-11,9	0	0	benign	0,39	neutral	0,14	neutral	4,23	neutral	-0,81	deleterious	-2,53	low_impact	1,7	neutral	0,9	damaging	0,12	neutral	1,7	14,4	0,33	0,65	neutral	0,3	neutral	0,35	disease	0,56	neutral	0,46	1	neutral	0,84	neutral	0,38	neutral	-6	neutral	0,36	medium_impact	-0,57	medium_impact	-0,15	medium_impact	0,36	0,72	0,9	15,49	18,89	N	0,38	N	0,68	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7770	7770	A	T	MI.5580	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	185	62	E	V	gAa/gTa	7,21	1	0	probably_damaging	1	neutral	0,49	neutral	-0,46	deleterious	-8,6	deleterious	-6,96	high_impact	4,3	damaging	0,27	neutral	0,28	deleterious	3,94	23,5	0,17	0,45	NA	NA	disease	0,82	disease	0,84	disease	0,71	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	0,2	high_impact	2,93	0,7	0,85	68,72	19,33	P	0,88	P	0,82	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7770	7770	A	C	MI.5581	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	185	62	E	A	gAa/gCa	7,21	1	0	probably_damaging	1	neutral	0,5	neutral	-0,44	deleterious	-7,38	deleterious	-5,96	high_impact	4,65	damaging	0,28	neutral	0,35	deleterious	3,46	23	0,2	0,45	NA	NA	disease	0,66	disease	0,82	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,81	low_impact	-3,52	medium_impact	0,21	high_impact	3,25	0,58	0,8	68,72	19,33	P	0,91	P	0,66	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7771	7771	A	T	MI.5582	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	186	62	E	D	gaA/gaT	8,59	1	0	probably_damaging	0,98	neutral	0,2	neutral	-0,41	deleterious	-6,22	deleterious	-2,96	high_impact	4,11	damaging	0,3	neutral	0,3	deleterious	3,73	23,3	0,37	0,5	NA	NA	disease	0,65	disease	0,84	disease	0,68	4	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-2,3	medium_impact	-0,13	high_impact	2,75	0,69	0,85	68,72	19,33	P	0,82	P	0,81	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7771	7771	A	C	MI.5583	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	186	62	E	D	gaA/gaC	8,59	1	0	probably_damaging	0,98	neutral	0,2	neutral	-0,41	deleterious	-6,22	deleterious	-2,96	high_impact	4,11	damaging	0,3	neutral	0,3	deleterious	3,63	23,2	0,37	0,5	NA	NA	disease	0,65	disease	0,84	disease	0,68	4	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-2,3	medium_impact	-0,13	high_impact	2,75	0,69	0,85	68,72	19,33	P	0,82	P	0,81	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7772	7772	A	C	MI.5584	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	187	63	T	P	Acc/Ccc	-0,17	0,69	0	possibly_damaging	0,7	neutral	0,16	neutral	1,43	deleterious	-3,55	deleterious	-3,4	medium_impact	2,82	neutral	0,6	neutral	0,38	deleterious	3,05	22,4	0,11	0,4	NA	NA	disease	0,79	disease	0,51	disease	0,57	1	neutral	0,87	neutral	0,23	NA	0	deleterious	0,64	low_impact	-1,06	medium_impact	-0,19	medium_impact	1,54	0,66	0,8	69,16	15,32	N	0,32	N	0,9	polymorphism	0,59	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7772	7772	A	T	MI.5585	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	187	63	T	S	Acc/Tcc	-0,17	0,69	0	benign	0,11	neutral	0,33	neutral	1,46	neutral	-2,07	neutral	-1,98	low_impact	1,62	neutral	0,72	neutral	0,56	neutral	1,23	11,9	0,38	0,5	NA	NA	neutral	0,41	neutral	0,48	neutral	0,14	7	neutral	0,62	deleterious	0,61	neutral	-6	neutral	0,2	medium_impact	0,13	medium_impact	0,04	medium_impact	0,41	0,81	0,85	69,16	15,32	N	0,39	N	0,8	polymorphism	0,96	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7772	7772	A	G	MI.5586	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	187	63	T	A	Acc/Gcc	-0,17	0,69	0	benign	0,05	neutral	0,26	neutral	1,49	neutral	-1,28	neutral	-2,12	low_impact	1,92	neutral	0,78	neutral	0,63	deleterious	0,25	5,15	0,54	0,6	NA	NA	neutral	0,35	neutral	0,45	neutral	0,14	7	neutral	0,72	deleterious	0,61	neutral	-6	neutral	0,15	medium_impact	0,47	medium_impact	-0,05	medium_impact	0,7	0,51	0,8	69,16	15,32	N	0,36	N	0,65	polymorphism	0,88	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7773	7773	C	G	MI.5587	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	188	63	T	S	aCc/aGc	3,06	0,97	0	benign	0,11	neutral	0,33	neutral	1,46	neutral	-2,07	neutral	-1,98	low_impact	1,62	neutral	0,72	neutral	0,56	neutral	1,52	13,44	0,38	0,5	NA	NA	neutral	0,41	neutral	0,48	neutral	0,14	7	neutral	0,62	deleterious	0,61	neutral	-6	neutral	0,2	medium_impact	0,13	medium_impact	0,04	medium_impact	0,41	0,81	0,85	69,16	15,32	P	0,53	P	0,8	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7773	7773	C	A	MI.5588	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	188	63	T	N	aCc/aAc	3,06	0,97	0	possibly_damaging	0,59	neutral	0,22	neutral	1,44	deleterious	-3,27	deleterious	-2,97	medium_impact	2,82	neutral	0,66	neutral	0,53	deleterious	3,39	23	0,29	0,45	NA	NA	disease	0,58	disease	0,52	disease	0,53	1	neutral	0,78	neutral	0,32	NA	0	deleterious	0,58	medium_impact	-0,87	medium_impact	-0,1	medium_impact	1,54	0,77	0,85	69,16	15,32	N	0,48	N	0,87	polymorphism	0,91	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7773	7773	C	T	MI.5589	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	188	63	T	I	aCc/aTc	3,06	0,97	0	benign	0,01	neutral	1	neutral	1,76	neutral	1,13	neutral	-0,64	neutral_impact	-0,88	neutral	0,78	neutral	0,77	neutral	-0,91	0,03	0,29	0,45	NA	NA	neutral	0,23	neutral	0,35	neutral	0,14	7	neutral	0,01	deleterious	1	neutral	-6	neutral	0,13	medium_impact	1,14	high_impact	1,86	low_impact	-1,93	0,7	0,85	69,16	15,32	N	0,33	N	0,77	polymorphism	0,91	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8789	8789	T	C	MI.559	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	263	88	L	P	cTg/cCg	-1,95	0	0	probably_damaging	0,94	deleterious	0	neutral	4	deleterious	-5,85	deleterious	-6,11	high_impact	4	neutral	0,8	damaging	0,1	deleterious	3,8	23,4	0,15	0,65	disease	0,92	disease	0,75	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,85	low_impact	-1,89	low_impact	-1,4	high_impact	2,33	0,65	0,9	15,49	18,89	N	0,28	N	0,95	polymorphism	0,88	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7775	7775	G	C	MI.5590	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	190	64	V	L	Gtc/Ctc	-14,7	0	0	benign	0,01	neutral	0,87	neutral	1,57	neutral	-0,11	neutral	-1,72	low_impact	1,17	damaging	0,59	neutral	0,48	neutral	1,56	13,63	0,46	0,55	NA	NA	disease	0,52	neutral	0,42	neutral	0,2	6	neutral	0,1	deleterious	0,93	neutral	-6	neutral	0,17	medium_impact	1,14	medium_impact	0,66	medium_impact	-0,01	0,77	0,85	63,88	15,77	N	0,29	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7775	7775	G	T	MI.5591	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	190	64	V	F	Gtc/Ttc	-14,7	0	0	benign	0,18	neutral	0,84	neutral	1,33	deleterious	-3,09	deleterious	-3,72	low_impact	1,64	damaging	0,47	neutral	0,47	deleterious	1,94	15,83	0,23	0,45	NA	NA	disease	0,76	neutral	0,48	neutral	0,16	7	neutral	0,09	deleterious	0,83	neutral	-6	neutral	0,32	medium_impact	-0,11	medium_impact	0,6	medium_impact	0,43	0,7	0,85	63,88	15,77	N	0,34	N	0,68	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7775	7775	G	A	MI.5592	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	190	64	V	I	Gtc/Atc	-14,7	0	0	benign	0	neutral	0,97	neutral	1,86	neutral	1,1	neutral	0,17	neutral_impact	-0,85	neutral	0,86	neutral	0,99	neutral	-1,14	0,01	0,53	0,6	NA	NA	neutral	0,06	neutral	0,36	neutral	0,12	8	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,09	high_impact	2,08	medium_impact	1,04	low_impact	-1,9	0,82	0,85	63,88	15,77	N	0,36	N	0	polymorphism	1	0,01	.	.	.	.	.	colonic crypts, thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	7776	7776	T	C	MI.5593	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	191	64	V	A	gTc/gCc	0,29	0,08	0	benign	0,07	neutral	0,58	neutral	1,36	neutral	-2,07	deleterious	-3,83	low_impact	1,29	damaging	0,59	neutral	0,64	deleterious	0,42	6,75	0,37	0,5	NA	NA	neutral	0,31	disease	0,52	neutral	0,27	5	neutral	0,34	deleterious	0,76	neutral	-6	neutral	0,16	medium_impact	0,33	medium_impact	0,28	medium_impact	0,1	0,54	0,8	63,88	15,77	N	0,39	N	0,67	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7776	7776	T	G	MI.5594	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	191	64	V	G	gTc/gGc	0,29	0,08	0	benign	0,11	neutral	0,47	neutral	1,31	deleterious	-4,2	deleterious	-6,82	medium_impact	2,42	damaging	0,5	neutral	0,5	deleterious	1,91	15,64	0,24	0,45	NA	NA	disease	0,71	disease	0,69	disease	0,7	4	neutral	0,45	deleterious	0,68	neutral	-3	neutral	0,31	medium_impact	0,13	medium_impact	0,18	medium_impact	1,16	0,58	0,8	63,88	15,77	N	0,38	N	0,94	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7776	7776	T	A	MI.5595	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	191	64	V	D	gTc/gAc	0,29	0,08	0	benign	0,24	neutral	0,21	neutral	1,3	deleterious	-4,96	deleterious	-6,27	medium_impact	3,31	damaging	0,48	neutral	0,4	deleterious	2,58	20	0,1	0,4	NA	NA	disease	0,83	disease	0,77	disease	0,72	4	neutral	0,75	deleterious	0,49	neutral	-3	neutral	0,38	medium_impact	-0,25	medium_impact	-0,11	medium_impact	2	0,57	0,8	63,88	15,77	N	0,47	N	0,91	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7778	7778	T	C	MI.5596	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	193	65	W	R	Tga/Cga	-6,63	0	0	probably_damaging	1	neutral	0,1	neutral	-0,97	deleterious	-9,07	deleterious	-13,89	high_impact	4,24	damaging	0,3	damaging	0,18	deleterious	3,47	23	0,27	0,45	NA	NA	disease	0,91	disease	0,87	disease	0,75	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	-0,32	high_impact	2,87	0,34	0,8	67,84	19,21	P	0,61	P	0,96	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7778	7778	T	G	MI.5597	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	193	65	W	G	Tga/Gga	-6,63	0	0	probably_damaging	1	neutral	0,15	neutral	-0,97	deleterious	-9,78	deleterious	-12,91	high_impact	3,9	damaging	0,31	neutral	0,33	deleterious	3,79	23,4	0,24	0,45	NA	NA	disease	0,87	disease	0,84	disease	0,73	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,21	high_impact	2,55	0,3	0,8	67,84	19,21	P	0,63	P	0,98	polymorphism	0,99	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7779	7779	G	C	MI.5598	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	194	65	W	S	tGa/tCa	7,44	1	0	probably_damaging	1	neutral	0,11	neutral	-0,97	deleterious	-9,75	deleterious	-13,89	high_impact	4,24	damaging	0,3	neutral	0,29	deleterious	3,94	23,5	0,22	0,45	NA	NA	disease	0,91	disease	0,83	disease	0,74	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	-0,3	high_impact	2,87	0,26	0,8	67,84	19,21	P	0,65	P	0,97	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7779	7779	G	T	MI.5599	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	194	65	W	L	tGa/tTa	7,44	1	0	probably_damaging	1	neutral	0,45	neutral	-0,96	deleterious	-8,54	deleterious	-12,91	high_impact	4,58	damaging	0,33	neutral	0,36	deleterious	4,13	23,8	0,2	0,45	NA	NA	disease	0,84	disease	0,83	disease	0,71	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,16	high_impact	3,19	0,3	0,8	67,84	19,21	P	0,7	P	0,98	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8551	8551	T	G	MI.56	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	25	9	F	V	Ttc/Gtc	0,59	0,99	0	probably_damaging	0,95	deleterious	0	neutral	3,88	neutral	-1,51	deleterious	-6,14	medium_impact	3,24	damaging	0,54	neutral	0,62	deleterious	3,86	23,5	0,38	0,65	disease	0,62	disease	0,84	disease	0,84	disease	0,85	7	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,79	low_impact	-1,97	low_impact	-1,4	medium_impact	1,68	0,43	0,9	49,56	8,77	P	0,52	P	0,98	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8789	8789	T	G	MI.560	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	263	88	L	R	cTg/cGg	-1,95	0	0	probably_damaging	0,91	deleterious	0	neutral	4	deleterious	-5,44	deleterious	-5,19	high_impact	4	neutral	0,83	damaging	0,09	deleterious	4,05	23,7	0,15	0,65	disease	0,9	disease	0,79	disease	0,79	disease	0,76	5	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,83	low_impact	-1,71	low_impact	-1,4	high_impact	2,33	0,56	0,9	15,49	18,89	N	0,38	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7780	7780	A	T	MI.5600	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	195	65	W	C	tgA/tgT	9,29	1	0	probably_damaging	1	deleterious	0,04	neutral	-0,95	deleterious	-7,71	deleterious	-12,9	high_impact	4,24	damaging	0,27	damaging	0,19	deleterious	4,05	23,7	0,26	0,45	NA	NA	disease	0,88	disease	0,87	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,88	low_impact	-3,52	medium_impact	-0,56	high_impact	2,87	0,35	0,8	67,84	19,21	P	0,8	P	0,94	disease_causing	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7780	7780	A	C	MI.5601	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	195	65	W	C	tgA/tgC	9,29	1	0	probably_damaging	1	deleterious	0,04	neutral	-0,95	deleterious	-7,71	deleterious	-12,9	high_impact	4,24	damaging	0,27	damaging	0,19	deleterious	3,93	23,5	0,26	0,45	NA	NA	disease	0,88	disease	0,87	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,88	low_impact	-3,52	medium_impact	-0,56	high_impact	2,87	0,35	0,8	67,84	19,21	P	0,79	P	0,94	disease_causing	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7781	7781	A	T	MI.5602	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	196	66	T	S	Act/Tct	4,67	1	0	probably_damaging	0,97	neutral	0,38	neutral	0,49	deleterious	-3,49	deleterious	-3,95	high_impact	3,58	damaging	0,15	damaging	0,04	deleterious	3,26	22,8	0,35	0,5	NA	NA	disease	0,72	disease	0,77	disease	0,69	4	neutral	0,97	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-2,13	medium_impact	0,09	high_impact	2,25	0,75	0,85	69,16	19,07	P	0,88	P	0,8	disease_causing	0,79	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7781	7781	A	C	MI.5603	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	196	66	T	P	Act/Cct	4,67	1	0	probably_damaging	1	neutral	0,13	neutral	0,34	deleterious	-6,78	deleterious	-5,94	high_impact	4,62	damaging	0,17	damaging	0,06	deleterious	3,46	23	0,15	0,4	NA	NA	disease	0,82	disease	0,86	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,25	high_impact	3,23	0,61	0,8	69,16	19,07	P	0,87	P	0,9	disease_causing	0,98	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7781	7781	A	G	MI.5604	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	196	66	T	A	Act/Gct	4,67	1	0	probably_damaging	0,97	neutral	0,34	neutral	0,37	deleterious	-5,23	deleterious	-4,95	high_impact	4,27	damaging	0,22	damaging	0,1	deleterious	3,4	23	0,46	0,55	NA	NA	disease	0,66	disease	0,78	disease	0,68	4	neutral	0,97	neutral	0,19	deleterious	2	deleterious	0,79	low_impact	-2,13	medium_impact	0,05	high_impact	2,9	0,54	0,8	69,16	19,07	P	0,86	P	0,65	disease_causing	0,92	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7782	7782	C	G	MI.5605	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	197	66	T	S	aCt/aGt	6,98	1	0	probably_damaging	0,97	neutral	0,38	neutral	0,49	deleterious	-3,49	deleterious	-3,95	high_impact	3,58	damaging	0,15	damaging	0,04	deleterious	3,37	22,9	0,35	0,5	NA	NA	disease	0,72	disease	0,77	disease	0,69	4	neutral	0,97	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-2,13	medium_impact	0,09	high_impact	2,25	0,75	0,85	69,16	19,07	P	0,87	P	0,8	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7782	7782	C	T	MI.5606	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	197	66	T	I	aCt/aTt	6,98	1	0	probably_damaging	1	neutral	0,37	neutral	0,35	deleterious	-5,78	deleterious	-5,95	high_impact	4,27	damaging	0,16	damaging	0,02	deleterious	3,78	23,4	0,38	0,5	NA	NA	disease	0,87	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,08	high_impact	2,9	0,72	0,85	69,16	19,07	P	0,83	P	0,77	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7782	7782	C	A	MI.5607	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	197	66	T	N	aCt/aAt	6,98	1	0	probably_damaging	1	neutral	0,23	neutral	0,35	deleterious	-5,95	deleterious	-4,95	high_impact	4,62	damaging	0,16	damaging	0,03	deleterious	3,64	23,2	0,39	0,5	NA	NA	disease	0,81	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,09	high_impact	3,23	0,78	0,85	69,16	19,07	P	0,85	P	0,87	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7784	7784	A	T	MI.5608	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	199	67	I	F	Atc/Ttc	-12,85	0	0	benign	0,18	neutral	0,09	neutral	1,14	deleterious	-3,84	deleterious	-3,7	medium_impact	2,45	damaging	0,46	neutral	0,29	deleterious	2,1	16,85	0,48	0,55	NA	NA	disease	0,78	disease	0,7	disease	0,67	3	neutral	0,9	neutral	0,46	neutral	-3	neutral	0,35	medium_impact	-0,11	medium_impact	-0,35	medium_impact	1,19	0,75	0,85	67,4	18,75	N	0,34	N	0,93	polymorphism	0,94	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7784	7784	A	G	MI.5609	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	199	67	I	V	Atc/Gtc	-12,85	0	0	benign	0	neutral	0,33	neutral	1,42	neutral	-0,68	neutral	-0,48	low_impact	1	neutral	0,8	neutral	0,89	neutral	-0,75	0,06	0,68	0,7	NA	NA	neutral	0,16	neutral	0,42	neutral	0,2	6	neutral	0,67	deleterious	0,67	neutral	-6	neutral	0,14	high_impact	2,08	medium_impact	0,04	medium_impact	-0,17	0,61	0,8	67,4	18,75	N	0,4	N	0,28	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8789	8789	T	A	MI.561	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	263	88	L	Q	cTg/cAg	-1,95	0	0	probably_damaging	0,94	deleterious	0	neutral	4	deleterious	-5,48	deleterious	-5,18	high_impact	4	neutral	0,8	damaging	0,11	deleterious	4,09	23,7	0,19	0,65	disease	0,91	disease	0,73	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,81	low_impact	-1,89	low_impact	-1,4	high_impact	2,33	0,66	0,9	15,49	18,89	N	0,3	N	0,91	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7784	7784	A	C	MI.5610	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	199	67	I	L	Atc/Ctc	-12,85	0	0	benign	0,01	neutral	0,38	neutral	1,29	neutral	-1,49	neutral	-1,73	low_impact	1,51	neutral	0,66	neutral	0,74	deleterious	0,71	8,86	0,41	0,5	NA	NA	disease	0,54	neutral	0,44	neutral	0,15	7	neutral	0,61	deleterious	0,69	neutral	-6	neutral	0,19	medium_impact	1,14	medium_impact	0,09	medium_impact	0,31	0,68	0,85	67,4	18,75	N	0,41	N	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7785	7785	T	A	MI.5611	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	200	67	I	N	aTc/aAc	0,29	0,02	0	benign	0,2	deleterious	0,02	neutral	1,12	deleterious	-5,05	deleterious	-6,21	high_impact	4,08	damaging	0,53	damaging	0,28	deleterious	2,6	20,2	0,37	0,5	NA	NA	disease	0,81	disease	0,71	disease	0,69	4	neutral	0,98	neutral	0,41	deleterious	2	neutral	0,4	medium_impact	-0,16	medium_impact	-0,73	high_impact	2,72	0,64	0,8	67,4	18,75	N	0,35	N	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7785	7785	T	G	MI.5612	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	200	67	I	S	aTc/aGc	0,29	0,02	0	benign	0,13	neutral	0,11	neutral	1,14	deleterious	-3,92	deleterious	-5,17	medium_impact	2,64	damaging	0,53	neutral	0,36	deleterious	2,3	18,19	0,38	0,5	NA	NA	disease	0,83	disease	0,69	disease	0,66	3	neutral	0,88	deleterious	0,49	neutral	-3	neutral	0,29	medium_impact	0,05	medium_impact	-0,3	medium_impact	1,37	0,55	0,8	67,4	18,75	N	0,33	N	0,9	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7785	7785	T	C	MI.5613	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	200	67	I	T	aTc/aCc	0,29	0,02	0	benign	0	neutral	0,26	neutral	1,2	neutral	-2,47	deleterious	-3,95	medium_impact	2,1	neutral	0,64	neutral	0,36	neutral	1,33	12,44	0,57	0,65	NA	NA	disease	0,66	disease	0,62	disease	0,54	1	neutral	0,74	deleterious	0,63	neutral	-3	neutral	0,21	high_impact	2,08	medium_impact	-0,05	medium_impact	0,86	0,57	0,8	67,4	18,75	N	0,37	N	0,91	polymorphism	1	0,12	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	7786	7786	C	A	MI.5614	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	201	67	I	M	atC/atA	5,83	0,89	0	benign	0,32	neutral	0,05	neutral	1,16	deleterious	-3,33	neutral	-2,5	medium_impact	2,4	damaging	0,59	neutral	0,39	deleterious	2,08	16,75	0,64	0,7	NA	NA	disease	0,56	neutral	0,46	neutral	0,15	7	neutral	0,94	neutral	0,37	neutral	-3	neutral	0,25	medium_impact	-0,42	medium_impact	-0,5	medium_impact	1,15	0,89	0,9	67,4	18,75	N	0,48	N	0,77	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7786	7786	C	G	MI.5615	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	201	67	I	M	atC/atG	5,83	0,89	0	benign	0,32	neutral	0,05	neutral	1,16	deleterious	-3,33	neutral	-2,5	medium_impact	2,4	damaging	0,59	neutral	0,39	neutral	1,61	13,91	0,64	0,7	NA	NA	disease	0,56	neutral	0,46	neutral	0,15	7	neutral	0,94	neutral	0,37	neutral	-3	neutral	0,25	medium_impact	-0,42	medium_impact	-0,5	medium_impact	1,15	0,89	0,9	67,4	18,75	N	0,48	N	0,77	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7787	7787	C	G	MI.5616	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	202	68	L	V	Ctg/Gtg	-3,86	0	0	probably_damaging	0,94	neutral	0,37	neutral	1,49	neutral	1,05	neutral	-2,4	medium_impact	2,05	damaging	0,53	damaging	0,2	deleterious	3,26	22,8	0,47	0,55	NA	NA	disease	0,52	neutral	0,43	neutral	0,17	7	neutral	0,94	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-1,83	medium_impact	0,08	medium_impact	0,82	0,48	0,8	68,28	18,9	N	0,34	N	0,6	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7787	7787	C	A	MI.5617	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	202	68	L	M	Ctg/Atg	-3,86	0	0	probably_damaging	1	neutral	0,22	neutral	1,35	neutral	-2,09	neutral	-1,01	low_impact	1,55	damaging	0,6	neutral	0,57	deleterious	2,49	19,42	0,34	0,5	NA	NA	neutral	0,35	neutral	0,4	neutral	0,15	7	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,76	low_impact	-3,52	medium_impact	-0,1	medium_impact	0,35	0,56	0,8	68,28	18,9	N	0,48	N	0,23	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7788	7788	T	A	MI.5618	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	203	68	L	Q	cTg/cAg	-2,01	0	0	probably_damaging	1	neutral	0,2	neutral	1,32	deleterious	-3,24	deleterious	-5,07	high_impact	4,01	damaging	0,38	damaging	0,05	deleterious	4,12	23,8	0,2	0,45	NA	NA	disease	0,74	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	-0,13	high_impact	2,65	0,62	0,8	68,28	18,9	N	0,43	N	0,89	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7788	7788	T	G	MI.5619	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	203	68	L	R	cTg/cGg	-2,01	0	0	probably_damaging	1	neutral	0,2	neutral	1,32	deleterious	-3,07	deleterious	-5,26	high_impact	4,01	damaging	0,25	damaging	0,01	deleterious	4,13	23,8	0,17	0,45	NA	NA	disease	0,88	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	-0,13	high_impact	2,65	0,48	0,8	68,28	18,9	P	0,69	P	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8791	8791	C	A	MI.562	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	265	89	P	T	Cct/Act	-7,28	0	0	probably_damaging	1	deleterious	0,02	neutral	2,16	deleterious	-6,12	deleterious	-7,12	high_impact	4,29	neutral	0,61	damaging	0,06	deleterious	3,64	23,2	0,21	0,65	disease	0,74	disease	0,69	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,6	medium_impact	-0,66	high_impact	2,58	0,61	0,9	49,12	8,71	N	0,3	N	0,93	disease_causing	0,77	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7788	7788	T	C	MI.5620	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	203	68	L	P	cTg/cCg	-2,01	0	0	probably_damaging	1	neutral	0,31	neutral	1,31	deleterious	-3,65	deleterious	-6,2	high_impact	4,01	damaging	0,23	damaging	0,03	deleterious	3,84	23,4	0,17	0,45	NA	NA	disease	0,87	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,01	high_impact	2,65	0,45	0,8	68,28	18,9	P	0,67	P	0,95	polymorphism	0,96	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7790	7790	C	A	MI.5621	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	205	69	P	T	Ccc/Acc	-8,47	0	0	probably_damaging	1	neutral	0,19	neutral	-1,39	deleterious	-9,49	deleterious	-7,93	high_impact	4,62	damaging	0,12	damaging	0,02	deleterious	3,62	23,2	0,24	0,45	NA	NA	disease	0,79	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	-0,14	high_impact	3,23	0,6	0,8	68,28	19,34	P	0,51	P	0,96	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7790	7790	C	T	MI.5622	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	205	69	P	S	Ccc/Tcc	-8,47	0	0	probably_damaging	1	neutral	0,15	neutral	-1,38	deleterious	-9,05	deleterious	-7,92	high_impact	4,28	damaging	0,11	damaging	0,03	deleterious	3,8	23,4	0,24	0,45	NA	NA	disease	0,83	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	-0,21	high_impact	2,91	0,28	0,8	68,28	19,34	P	0,52	P	0,94	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7790	7790	C	G	MI.5623	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	205	69	P	A	Ccc/Gcc	-8,47	0	0	probably_damaging	1	neutral	0,35	neutral	-1,38	deleterious	-8,75	deleterious	-7,93	high_impact	4,62	damaging	0,13	damaging	0,11	deleterious	3,02	22,3	0,19	0,45	NA	NA	disease	0,71	disease	0,7	disease	0,66	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	0,06	high_impact	3,23	0,58	0,8	68,28	19,34	P	0,57	P	0,9	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7791	7791	C	A	MI.5624	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	206	69	P	H	cCc/cAc	7,21	1	0	probably_damaging	1	neutral	0,14	neutral	-1,4	deleterious	-11,09	deleterious	-8,92	high_impact	4,28	damaging	0,08	damaging	0,02	deleterious	3,9	23,5	0,16	0,45	NA	NA	disease	0,87	disease	0,79	disease	0,69	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,23	high_impact	2,91	0,57	0,8	68,28	19,34	P	0,78	P	0,79	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7791	7791	C	G	MI.5625	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	206	69	P	R	cCc/cGc	7,21	1	0	probably_damaging	1	neutral	0,2	neutral	-1,39	deleterious	-10,07	deleterious	-8,92	high_impact	4,62	damaging	0,12	damaging	0,02	deleterious	3,51	23,1	0,15	0,4	NA	NA	disease	0,91	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	-0,13	high_impact	3,23	0,53	0,8	68,28	19,34	P	0,76	P	0,85	disease_causing	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7791	7791	C	T	MI.5626	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	206	69	P	L	cCc/cTc	7,21	1	0	probably_damaging	1	neutral	0,26	neutral	-1,39	deleterious	-9,97	deleterious	-9,91	high_impact	4,62	damaging	0,07	damaging	0,02	deleterious	4,36	24,1	0,21	0,45	NA	NA	disease	0,89	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,05	high_impact	3,23	0,7	0,85	68,28	19,34	P	0,74	P	0,92	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7793	7793	G	T	MI.5627	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	208	70	A	S	Gcc/Tcc	-2,24	0	0	probably_damaging	0,99	neutral	0,42	neutral	1,26	neutral	-2,03	deleterious	-2,89	medium_impact	2,4	damaging	0,46	neutral	0,52	deleterious	3,64	23,2	0,42	0,55	NA	NA	disease	0,74	disease	0,59	neutral	0,39	2	deleterious	0,99	neutral	0,22	deleterious	1	deleterious	0,84	low_impact	-2,58	medium_impact	0,13	medium_impact	1,15	0,77	0,85	68,72	19,4	N	0,42	N	0,71	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7793	7793	G	A	MI.5628	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	208	70	A	T	Gcc/Acc	-2,24	0	0	probably_damaging	1	neutral	0,46	neutral	1,34	neutral	-1,32	deleterious	-3,82	medium_impact	2,36	damaging	0,32	neutral	0,34	deleterious	4,13	23,8	0,46	0,55	NA	NA	disease	0,69	neutral	0,49	neutral	0,15	7	deleterious	0,99	neutral	0,23	deleterious	1	deleterious	0,84	low_impact	-3,52	medium_impact	0,17	medium_impact	1,11	0,72	0,85	68,72	19,4	P	0,63	P	0,72	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7793	7793	G	C	MI.5629	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	208	70	A	P	Gcc/Ccc	-2,24	0	0	probably_damaging	1	neutral	0,25	neutral	1,19	deleterious	-4,3	deleterious	-4,89	medium_impact	2,98	damaging	0,28	neutral	0,29	deleterious	3,8	23,4	0,18	0,45	NA	NA	disease	0,87	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,91	low_impact	-3,52	medium_impact	-0,06	medium_impact	1,69	0,69	0,85	68,72	19,4	P	0,83	P	0,9	polymorphism	0,99	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8791	8791	C	G	MI.563	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	265	89	P	A	Cct/Gct	-7,28	0	0	probably_damaging	1	deleterious	0	neutral	2,15	deleterious	-6,18	deleterious	-7,13	high_impact	4,64	neutral	0,61	damaging	0,1	deleterious	3	22,2	0,19	0,65	disease	0,86	neutral	0,48	disease	0,69	disease	0,66	3	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,6	low_impact	-1,4	high_impact	2,88	0,67	0,9	49,12	8,71	N	0,42	N	0,79	disease_causing	0,68	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7794	7794	C	T	MI.5630	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	209	70	A	V	gCc/gTc	9,29	1	0	probably_damaging	0,99	neutral	0,51	neutral	1,32	neutral	-0,35	deleterious	-3,9	medium_impact	2,17	damaging	0,35	neutral	0,32	deleterious	4,39	24,1	0,38	0,5	NA	NA	disease	0,73	disease	0,51	neutral	0,14	7	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,86	low_impact	-2,58	medium_impact	0,21	medium_impact	0,93	0,75	0,85	68,72	19,4	P	0,78	P	0,79	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7794	7794	C	G	MI.5631	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	209	70	A	G	gCc/gGc	9,29	1	0	probably_damaging	0,98	neutral	0,33	neutral	1,2	deleterious	-3,11	deleterious	-3,94	medium_impact	2,98	damaging	0,37	neutral	0,48	deleterious	3,89	23,5	0,33	0,5	NA	NA	disease	0,72	disease	0,65	disease	0,54	1	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,81	low_impact	-2,3	medium_impact	0,04	medium_impact	1,69	0,67	0,85	68,72	19,4	P	0,77	P	0,74	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7794	7794	C	A	MI.5632	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	209	70	A	D	gCc/gAc	9,29	1	0	probably_damaging	1	neutral	0,23	neutral	1,2	deleterious	-4,23	deleterious	-5,87	high_impact	4,26	damaging	0,34	neutral	0,3	deleterious	4,47	24,2	0,18	0,45	NA	NA	disease	0,89	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,09	high_impact	2,89	0,58	0,8	68,72	19,4	P	0,8	P	0,94	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7796	7796	A	C	MI.5633	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	211	71	I	L	Atc/Ctc	-9,85	0	0	benign	0,06	neutral	0,43	neutral	1,61	neutral	0,12	neutral	-1,34	low_impact	1,15	neutral	0,75	neutral	0,78	deleterious	0,61	8,22	0,33	0,5	NA	NA	neutral	0,45	neutral	0,36	neutral	0,16	7	neutral	0,52	deleterious	0,69	neutral	-6	neutral	0,17	medium_impact	0,39	medium_impact	0,14	medium_impact	-0,03	0,52	0,8	66,52	14,61	N	0,38	N	0,6	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7796	7796	A	T	MI.5634	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	211	71	I	F	Atc/Ttc	-9,85	0	0	possibly_damaging	0,59	neutral	0,23	neutral	1,37	neutral	-1,42	deleterious	-2,69	low_impact	0,84	neutral	0,68	neutral	0,5	deleterious	0,8	9,48	0,36	0,5	NA	NA	disease	0,51	neutral	0,44	neutral	0,18	6	neutral	0,77	neutral	0,32	neutral	-3	deleterious	0,55	medium_impact	-0,87	medium_impact	-0,09	medium_impact	-0,32	0,59	0,8	66,52	14,61	N	0,35	N	0,83	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7796	7796	A	G	MI.5635	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	211	71	I	V	Atc/Gtc	-9,85	0	0	benign	0	neutral	0,45	neutral	1,6	neutral	0,05	neutral	-0,59	neutral_impact	0,39	neutral	0,84	neutral	0,87	neutral	-0,59	0,13	0,51	0,6	NA	NA	neutral	0,14	neutral	0,38	neutral	0,21	6	neutral	0,55	deleterious	0,73	neutral	-6	neutral	0,12	high_impact	2,08	medium_impact	0,16	medium_impact	-0,74	0,35	0,8	66,52	14,61	N	0,39	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7797	7797	T	A	MI.5636	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	212	71	I	N	aTc/aAc	0,06	0	0	probably_damaging	0,94	deleterious	0,03	neutral	1,24	deleterious	-5,2	deleterious	-5,82	high_impact	3,66	damaging	0,6	neutral	0,29	deleterious	4,2	23,9	0,23	0,45	NA	NA	disease	0,74	disease	0,65	disease	0,68	4	deleterious	0,99	neutral	0,05	deleterious	6	deleterious	0,75	low_impact	-1,83	medium_impact	-0,63	high_impact	2,33	0,56	0,8	66,52	14,61	N	0,3	N	0,95	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7797	7797	T	G	MI.5637	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	212	71	I	S	aTc/aGc	0,06	0	0	possibly_damaging	0,76	neutral	0,09	neutral	1,25	deleterious	-4,02	deleterious	-4,71	medium_impact	2,97	damaging	0,57	neutral	0,35	deleterious	3,85	23,4	0,27	0,45	NA	NA	disease	0,76	disease	0,61	disease	0,67	3	neutral	0,94	neutral	0,17	NA	0	deleterious	0,56	low_impact	-1,19	medium_impact	-0,35	medium_impact	1,68	0,42	0,8	66,52	14,61	N	0,32	N	0,84	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7797	7797	T	C	MI.5638	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	212	71	I	T	aTc/aCc	0,06	0	0	possibly_damaging	0,5	neutral	0,26	neutral	1,26	deleterious	-3,38	deleterious	-3,75	medium_impact	2,97	damaging	0,59	neutral	0,37	neutral	1,6	13,83	0,4	0,5	NA	NA	disease	0,5	disease	0,6	disease	0,57	1	neutral	0,72	neutral	0,38	NA	0	neutral	0,36	medium_impact	-0,72	medium_impact	-0,05	medium_impact	1,68	0,54	0,8	66,52	14,61	N	0,36	N	0,84	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7798	7798	C	A	MI.5639	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	213	71	I	M	atC/atA	3,06	0,17	0	possibly_damaging	0,76	neutral	0,07	neutral	1,3	neutral	-2,44	neutral	-2,04	low_impact	1,3	neutral	0,77	neutral	0,78	deleterious	0,74	9,08	0,38	0,5	NA	NA	neutral	0,3	neutral	0,41	neutral	0,16	7	neutral	0,95	neutral	0,16	neutral	-3	neutral	0,43	low_impact	-1,19	medium_impact	-0,42	medium_impact	0,11	0,64	0,8	66,52	14,61	N	0,41	N	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8791	8791	C	T	MI.564	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	265	89	P	S	Cct/Tct	-7,28	0	0	probably_damaging	1	deleterious	0,02	neutral	2,15	deleterious	-6,47	deleterious	-7,08	high_impact	4,09	damaging	0,6	damaging	0,07	deleterious	3,81	23,4	0,25	0,65	disease	0,88	disease	0,7	disease	0,73	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,6	medium_impact	-0,66	high_impact	2,41	0,42	0,9	49,12	8,71	N	0,27	N	0,82	disease_causing	0,78	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7798	7798	C	G	MI.5640	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	213	71	I	M	atC/atG	3,06	0,17	0	possibly_damaging	0,76	neutral	0,07	neutral	1,3	neutral	-2,44	neutral	-2,04	low_impact	1,3	neutral	0,77	neutral	0,78	deleterious	0,21	4,83	0,38	0,5	NA	NA	neutral	0,3	neutral	0,41	neutral	0,16	7	neutral	0,95	neutral	0,16	neutral	-3	neutral	0,43	low_impact	-1,19	medium_impact	-0,42	medium_impact	0,11	0,64	0,8	66,52	14,61	N	0,41	N	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7799	7799	A	G	MI.5641	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	214	72	I	V	Atc/Gtc	-6,16	0	0	probably_damaging	0,92	neutral	0,48	neutral	1,13	neutral	-1,71	neutral	-0,4	low_impact	1,64	neutral	0,71	neutral	0,54	neutral	1,56	13,63	0,45	0,55	NA	NA	neutral	0,14	neutral	0,46	neutral	0,2	6	neutral	0,92	neutral	0,28	neutral	-2	deleterious	0,58	low_impact	-1,71	medium_impact	0,19	medium_impact	0,43	0,46	0,8	68,28	19,06	N	0,37	N	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7799	7799	A	T	MI.5642	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	214	72	I	F	Atc/Ttc	-6,16	0	0	probably_damaging	1	neutral	0,21	neutral	0,91	deleterious	-4,62	deleterious	-3,73	medium_impact	2,68	damaging	0,37	damaging	0,06	deleterious	3,71	23,3	0,32	0,5	NA	NA	disease	0,75	disease	0,63	disease	0,64	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	-0,11	medium_impact	1,41	0,73	0,85	68,28	19,06	N	0,41	N	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7799	7799	A	C	MI.5643	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	214	72	I	L	Atc/Ctc	-6,16	0	0	probably_damaging	0,97	neutral	0,53	neutral	1,07	neutral	-2,14	neutral	-1,81	medium_impact	2,27	damaging	0,36	damaging	0,12	deleterious	3,74	23,3	0,29	0,45	NA	NA	disease	0,62	disease	0,56	neutral	0,47	1	neutral	0,97	neutral	0,28	deleterious	1	deleterious	0,63	low_impact	-2,13	medium_impact	0,23	medium_impact	1,02	0,57	0,8	68,28	19,06	N	0,46	N	0,71	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7800	7800	T	A	MI.5644	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	215	72	I	N	aTc/aAc	4,67	1	0	probably_damaging	1	neutral	0,19	neutral	0,89	deleterious	-6,14	deleterious	-6,07	high_impact	3,88	damaging	0,38	damaging	0,07	deleterious	4,41	24,1	0,17	0,45	NA	NA	disease	0,79	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,8	low_impact	-3,52	medium_impact	-0,14	high_impact	2,53	0,55	0,8	68,28	19,06	P	0,59	P	0,99	disease_causing	0,83	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7800	7800	T	C	MI.5645	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	215	72	I	T	aTc/aCc	4,67	1	0	probably_damaging	1	neutral	0,52	neutral	0,98	deleterious	-3,06	deleterious	-3,62	low_impact	1,87	damaging	0,44	damaging	0,17	deleterious	2,27	17,99	0,38	0,5	NA	NA	neutral	0,23	neutral	0,5	neutral	0,16	7	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,71	low_impact	-3,52	medium_impact	0,22	medium_impact	0,65	0,51	0,8	68,28	19,06	P	0,63	P	0,96	disease_causing	0,61	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7800	7800	T	G	MI.5646	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	215	72	I	S	aTc/aGc	4,67	1	0	probably_damaging	1	neutral	0,05	neutral	0,9	deleterious	-5,02	deleterious	-5,08	high_impact	4,23	damaging	0,37	damaging	0,1	deleterious	4,25	23,9	0,21	0,45	NA	NA	disease	0,79	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,79	low_impact	-3,52	medium_impact	-0,5	high_impact	2,86	0,49	0,8	68,28	19,06	P	0,65	P	0,91	disease_causing	0,86	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7801	7801	C	A	MI.5647	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	216	72	I	M	atC/atA	5,6	1	0	probably_damaging	1	neutral	0,11	neutral	0,97	deleterious	-3,27	deleterious	-2,52	medium_impact	2,1	damaging	0,4	damaging	0,08	deleterious	3,81	23,4	0,37	0,5	NA	NA	disease	0,52	disease	0,61	disease	0,56	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,74	low_impact	-3,52	medium_impact	-0,3	medium_impact	0,86	0,7	0,85	68,28	19,06	P	0,64	P	0,79	disease_causing	0,75	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7801	7801	C	G	MI.5648	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	216	72	I	M	atC/atG	5,6	1	0	probably_damaging	1	neutral	0,11	neutral	0,97	deleterious	-3,27	deleterious	-2,52	medium_impact	2,1	damaging	0,4	damaging	0,08	deleterious	3,34	22,9	0,37	0,5	NA	NA	disease	0,52	disease	0,61	disease	0,56	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,74	low_impact	-3,52	medium_impact	-0,3	medium_impact	0,86	0,7	0,85	68,28	19,06	P	0,63	P	0,79	disease_causing	0,75	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7802	7802	C	A	MI.5649	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	217	73	L	M	Cta/Ata	-4,32	0	0	probably_damaging	1	neutral	0,06	neutral	0,34	deleterious	-5,4	neutral	-1,92	high_impact	3,68	damaging	0,25	damaging	0,2	deleterious	3,58	23,2	0,28	0,45	NA	NA	disease	0,57	disease	0,58	disease	0,52	0	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,8	low_impact	-3,52	medium_impact	-0,46	high_impact	2,35	0,56	0,8	68,72	19,46	P	0,83	P	0,78	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8792	8792	C	T	MI.565	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	266	89	P	L	cCt/cTt	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,13	deleterious	-7,26	deleterious	-9,02	high_impact	4,29	damaging	0,55	damaging	0,05	deleterious	4,31	24	0,21	0,65	disease	0,95	disease	0,77	disease	0,72	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,6	low_impact	-1,4	high_impact	2,58	0,77	0,9	49,12	8,71	N	0,48	N	0,95	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7802	7802	C	G	MI.5650	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	217	73	L	V	Cta/Gta	-4,32	0	0	probably_damaging	0,99	neutral	0,16	neutral	0,5	deleterious	-3,2	deleterious	-2,94	high_impact	3,88	damaging	0,17	damaging	0,02	deleterious	3,34	22,9	0,27	0,45	NA	NA	disease	0,65	disease	0,67	disease	0,65	3	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-2,58	medium_impact	-0,19	high_impact	2,53	0,46	0,8	68,72	19,46	P	0,71	P	0,66	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7803	7803	T	G	MI.5651	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	218	73	L	R	cTa/cGa	-0,17	0	0	probably_damaging	1	deleterious	0,02	neutral	0,3	deleterious	-7,94	deleterious	-5,91	high_impact	4,57	damaging	0,21	damaging	0,01	deleterious	4,11	23,7	0,13	0,4	NA	NA	disease	0,87	disease	0,77	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,92	low_impact	-3,52	medium_impact	-0,73	high_impact	3,18	0,36	0,8	68,72	19,46	P	0,72	P	0,99	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7803	7803	T	C	MI.5652	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	218	73	L	P	cTa/cCa	-0,17	0	0	probably_damaging	1	deleterious	0,04	neutral	0,3	deleterious	-7,67	deleterious	-6,91	high_impact	4,22	damaging	0,18	damaging	0,02	deleterious	3,85	23,4	0,14	0,4	NA	NA	disease	0,8	disease	0,76	disease	0,68	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,9	low_impact	-3,52	medium_impact	-0,56	high_impact	2,85	0,54	0,8	68,72	19,46	P	0,7	P	0,99	polymorphism	0,79	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7803	7803	T	A	MI.5653	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	218	73	L	Q	cTa/cAa	-0,17	0	0	probably_damaging	1	deleterious	0,01	neutral	0,3	deleterious	-7,68	deleterious	-5,9	high_impact	4,22	damaging	0,18	damaging	0,02	deleterious	4,01	23,6	0,14	0,4	NA	NA	disease	0,78	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,52	medium_impact	-0,9	high_impact	2,85	0,47	0,8	68,72	19,46	P	0,69	P	0,95	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7805	7805	G	T	MI.5654	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	220	74	V	F	Gtc/Ttc	-4,09	0	0,01	benign	0,33	neutral	0,15	neutral	1,37	neutral	-1,62	deleterious	-3,05	low_impact	1,28	damaging	0,56	neutral	0,56	deleterious	2,07	16,68	0,22	0,45	NA	NA	disease	0,74	disease	0,54	neutral	0,21	6	neutral	0,82	neutral	0,41	neutral	-6	deleterious	0,44	medium_impact	-0,43	medium_impact	-0,21	medium_impact	0,1	0,64	0,8	47,14	14,51	N	0,34	N	0,67	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7805	7805	G	A	MI.5655	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	220	74	V	I	Gtc/Atc	-4,09	0	0,01	benign	0	neutral	1	neutral	1,72	neutral	0,55	neutral	0,57	neutral_impact	-1,18	neutral	0,81	neutral	0,99	neutral	-1,1	0,01	0,46	0,55	NA	NA	neutral	0,05	neutral	0,29	neutral	0,12	8	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,08	high_impact	1,86	low_impact	-2,21	0,67	0,85	47,14	14,51	N	0,35	N	0	polymorphism	1	0,01	rs879119797	.	.	.	.	.	COSM1138406	.	.	.	.	.	.	.	.
chrM	7805	7805	G	C	MI.5656	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	220	74	V	L	Gtc/Ctc	-4,09	0	0,01	benign	0,02	neutral	0,61	neutral	1,56	neutral	-0,12	neutral	-1,19	neutral_impact	0,64	neutral	0,66	neutral	0,57	deleterious	0,32	5,87	0,35	0,5	NA	NA	neutral	0,4	neutral	0,37	neutral	0,13	7	neutral	0,36	deleterious	0,8	neutral	-6	neutral	0,16	medium_impact	0,86	medium_impact	0,31	medium_impact	-0,51	0,44	0,8	47,14	14,51	N	0,29	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7806	7806	T	G	MI.5657	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	221	74	V	G	gTc/gGc	1,91	0,92	0	benign	0,31	neutral	0,15	neutral	1,26	deleterious	-4,88	deleterious	-6,38	medium_impact	2,46	damaging	0,57	neutral	0,48	deleterious	2,02	16,35	0,17	0,45	NA	NA	disease	0,68	disease	0,59	disease	0,68	4	neutral	0,82	neutral	0,42	neutral	-3	neutral	0,31	medium_impact	-0,4	medium_impact	-0,21	medium_impact	1,2	0,5	0,8	47,14	14,51	N	0,42	N	0,94	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7806	7806	T	A	MI.5658	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	221	74	V	D	gTc/gAc	1,91	0,92	0	possibly_damaging	0,49	deleterious	0,01	neutral	1,25	deleterious	-5,82	deleterious	-5,51	medium_impact	3	damaging	0,53	neutral	0,4	deleterious	3	22,2	0,08	0,35	NA	NA	disease	0,82	disease	0,72	disease	0,72	4	deleterious	0,99	neutral	0,26	deleterious	4	deleterious	0,52	medium_impact	-0,7	medium_impact	-0,9	medium_impact	1,71	0,47	0,8	47,14	14,51	N	0,39	N	0,91	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7806	7806	T	C	MI.5659	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	221	74	V	A	gTc/gCc	1,91	0,92	0	benign	0,1	neutral	0,1	neutral	1,29	neutral	-2,93	deleterious	-3,5	medium_impact	2,03	neutral	0,64	neutral	0,66	neutral	1,69	14,33	0,32	0,5	NA	NA	neutral	0,44	disease	0,57	neutral	0,38	2	neutral	0,89	deleterious	0,5	neutral	-3	neutral	0,2	medium_impact	0,17	medium_impact	-0,32	medium_impact	0,8	0,38	0,8	47,14	14,51	N	0,46	N	0,66	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8792	8792	C	G	MI.566	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	266	89	P	R	cCt/cGt	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,12	deleterious	-7,83	deleterious	-8,1	high_impact	4,64	neutral	0,61	damaging	0,06	deleterious	3,54	23,1	0,16	0,65	disease	0,97	disease	0,8	disease	0,82	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,88	0,63	0,9	49,12	8,71	P	0,56	P	0,65	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7808	7808	C	G	MI.5660	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	223	75	L	V	Ctc/Gtc	-5,7	0	0	probably_damaging	0,97	neutral	0,28	neutral	1,45	neutral	-0,07	neutral	-0,72	neutral_impact	0,77	neutral	0,75	neutral	0,77	neutral	1,73	14,57	0,41	0,5	NA	NA	disease	0,51	neutral	0,38	neutral	0,19	6	neutral	0,98	neutral	0,16	neutral	-2	deleterious	0,76	low_impact	-2,13	medium_impact	-0,02	medium_impact	-0,38	0,53	0,8	66,08	15,78	N	0,4	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7808	7808	C	A	MI.5661	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	223	75	L	I	Ctc/Atc	-5,7	0	0	probably_damaging	0,99	neutral	0,45	neutral	1,5	neutral	-0,45	neutral	-0,57	low_impact	1,22	neutral	0,69	neutral	0,66	deleterious	2,86	21,7	0,4	0,5	NA	NA	disease	0,5	neutral	0,35	neutral	0,18	6	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,76	low_impact	-2,58	medium_impact	0,16	medium_impact	0,04	0,58	0,8	66,08	15,78	N	0,35	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7808	7808	C	T	MI.5662	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	223	75	L	F	Ctc/Ttc	-5,7	0	0	probably_damaging	1	neutral	0,5	neutral	1,49	neutral	-1,04	neutral	-2,04	neutral_impact	-0,2	neutral	0,74	neutral	0,65	deleterious	1,91	15,66	0,43	0,55	NA	NA	neutral	0,07	neutral	0,26	neutral	0,15	7	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,72	low_impact	-3,52	medium_impact	0,21	low_impact	-1,29	0,54	0,8	66,08	15,78	N	0,31	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7809	7809	T	A	MI.5663	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	224	75	L	H	cTc/cAc	-2,71	0	0	probably_damaging	1	deleterious	0,03	neutral	1,33	deleterious	-4,21	deleterious	-4,42	medium_impact	2,77	damaging	0,6	neutral	0,44	deleterious	4,06	23,7	0,18	0,45	NA	NA	disease	0,72	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,81	low_impact	-3,52	medium_impact	-0,63	medium_impact	1,49	0,61	0,8	66,08	15,78	N	0,31	N	0,81	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7809	7809	T	C	MI.5664	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	224	75	L	P	cTc/cCc	-2,71	0	0	probably_damaging	1	neutral	0,08	neutral	1,33	deleterious	-4,26	deleterious	-4,32	medium_impact	3,11	damaging	0,55	neutral	0,31	deleterious	3,84	23,4	0,18	0,45	NA	NA	disease	0,89	disease	0,7	disease	0,74	5	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,89	low_impact	-3,52	medium_impact	-0,38	medium_impact	1,81	0,56	0,8	66,08	15,78	N	0,3	N	0,95	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7809	7809	T	G	MI.5665	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	224	75	L	R	cTc/cGc	-2,71	0	0	probably_damaging	1	deleterious	0,02	neutral	1,34	deleterious	-3,67	deleterious	-3,86	medium_impact	3,11	damaging	0,55	neutral	0,35	deleterious	4,12	23,8	0,2	0,45	NA	NA	disease	0,89	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,9	low_impact	-3,52	medium_impact	-0,73	medium_impact	1,81	0,64	0,8	66,08	15,78	N	0,3	N	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7811	7811	A	C	MI.5666	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	226	76	I	L	Atc/Ctc	-2,24	0	0	probably_damaging	0,98	neutral	0,51	neutral	1,53	neutral	-0,18	neutral	-1,68	low_impact	1,75	neutral	0,69	neutral	0,83	deleterious	0,73	9,04	0,35	0,5	NA	NA	disease	0,63	neutral	0,46	neutral	0,14	7	deleterious	0,98	neutral	0,27	neutral	-2	deleterious	0,59	low_impact	-2,3	medium_impact	0,21	medium_impact	0,54	0,48	0,8	69,16	19,08	N	0,32	N	0,71	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7811	7811	A	G	MI.5667	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	226	76	I	V	Atc/Gtc	-2,24	0	0	probably_damaging	0,95	neutral	0,36	neutral	1,16	neutral	-2,37	neutral	-0,89	medium_impact	2,83	damaging	0,56	neutral	0,45	deleterious	0,11	3,71	0,46	0,55	NA	NA	neutral	0,5	disease	0,54	neutral	0,2	6	neutral	0,96	neutral	0,21	deleterious	1	deleterious	0,72	low_impact	-1,91	medium_impact	0,07	medium_impact	1,55	0,33	0,8	69,16	19,08	N	0,43	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7811	7811	A	T	MI.5668	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	226	76	I	F	Atc/Ttc	-2,24	0	0	probably_damaging	1	deleterious	0,02	neutral	1,1	deleterious	-3,48	deleterious	-3,81	high_impact	3,72	damaging	0,49	damaging	0,28	deleterious	3,59	23,2	0,32	0,5	NA	NA	disease	0,82	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,52	medium_impact	-0,73	high_impact	2,38	0,59	0,8	69,16	19,08	N	0,39	N	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7812	7812	T	A	MI.5669	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	227	76	I	N	aTc/aAc	5,6	1	0	probably_damaging	1	deleterious	0,01	neutral	1,05	deleterious	-5,9	deleterious	-6,74	high_impact	4,42	damaging	0,53	neutral	0,29	deleterious	4,4	24,1	0,24	0,45	NA	NA	disease	0,83	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-3,52	medium_impact	-0,9	high_impact	3,04	0,37	0,8	69,16	19,08	N	0,48	N	0,99	disease_causing	0,99	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8792	8792	C	A	MI.567	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	266	89	P	H	cCt/cAt	7,3	1	0	probably_damaging	1	deleterious	0	neutral	2,11	deleterious	-8,99	deleterious	-8,1	high_impact	4,64	neutral	0,63	damaging	0,04	deleterious	3,85	23,4	0,21	0,65	disease	0,98	disease	0,79	disease	0,82	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,88	0,61	0,9	49,12	8,71	P	0,55	P	0,64	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7812	7812	T	G	MI.5670	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	227	76	I	S	aTc/aGc	5,6	1	0	probably_damaging	1	deleterious	0,01	neutral	1,06	deleterious	-5,13	deleterious	-5,75	high_impact	4,42	damaging	0,5	neutral	0,36	deleterious	4,19	23,9	0,29	0,45	NA	NA	disease	0,85	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-3,52	medium_impact	-0,9	high_impact	3,04	0,3	0,8	69,16	19,08	P	0,49	N	0,91	disease_causing	0,99	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7812	7812	T	C	MI.5671	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	227	76	I	T	aTc/aCc	5,6	1	0	probably_damaging	1	neutral	0,05	neutral	1,07	deleterious	-4,45	deleterious	-4,7	high_impact	3,72	damaging	0,54	neutral	0,33	neutral	1,72	14,53	0,41	0,5	NA	NA	disease	0,68	disease	0,67	disease	0,53	1	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,81	low_impact	-3,52	medium_impact	-0,5	high_impact	2,38	0,41	0,8	69,16	19,08	P	0,53	P	0,96	disease_causing	0,96	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7813	7813	C	G	MI.5672	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	228	76	I	M	atC/atG	5,83	1	0	probably_damaging	1	neutral	0,19	neutral	1,19	neutral	-2,08	deleterious	-2,7	medium_impact	2,81	neutral	0,61	neutral	0,37	deleterious	3,25	22,8	0,41	0,5	NA	NA	disease	0,67	disease	0,65	disease	0,54	1	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	-0,14	medium_impact	1,53	0,58	0,8	69,16	19,08	P	0,51	P	0,79	disease_causing	0,96	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7813	7813	C	A	MI.5673	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	228	76	I	M	atC/atA	5,83	1	0	probably_damaging	1	neutral	0,19	neutral	1,19	neutral	-2,08	deleterious	-2,7	medium_impact	2,81	neutral	0,61	neutral	0,37	deleterious	3,74	23,3	0,41	0,5	NA	NA	disease	0,67	disease	0,65	disease	0,54	1	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	-0,14	medium_impact	1,53	0,58	0,8	69,16	19,08	P	0,52	P	0,79	disease_causing	0,96	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7814	7814	G	C	MI.5674	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	229	77	A	P	Gcc/Ccc	-2,71	0	0	probably_damaging	1	neutral	0,14	neutral	0,59	deleterious	-6,24	deleterious	-4,96	high_impact	4,53	damaging	0,28	damaging	0,23	deleterious	3,74	23,3	0,15	0,4	NA	NA	disease	0,87	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	-0,23	high_impact	3,14	0,59	0,8	68,72	19,49	P	0,83	P	0,9	disease_causing	0,97	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7814	7814	G	T	MI.5675	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	229	77	A	S	Gcc/Tcc	-2,71	0	0	probably_damaging	1	neutral	0,3	neutral	0,68	deleterious	-3,66	deleterious	-2,97	medium_impact	3,17	damaging	0,26	neutral	0,3	deleterious	3,65	23,2	0,42	0,55	NA	NA	disease	0,8	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,88	low_impact	-3,52	medium_impact	0	medium_impact	1,87	0,62	0,8	68,72	19,49	P	0,84	P	0,71	disease_causing	0,78	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7814	7814	G	A	MI.5676	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	229	77	A	T	Gcc/Acc	-2,71	0	0	probably_damaging	1	neutral	0,39	neutral	0,63	deleterious	-4,63	deleterious	-3,94	medium_impact	3,43	damaging	0,29	damaging	0,25	deleterious	4,18	23,8	0,43	0,55	NA	NA	disease	0,75	disease	0,62	disease	0,55	1	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,86	low_impact	-3,52	medium_impact	0,1	high_impact	2,11	0,72	0,85	68,72	19,49	P	0,77	P	0,72	disease_causing	0,89	0,22	.	.	.	.	.	.	COSM1155680	.	.	.	.	.	.	.	.
chrM	7815	7815	C	A	MI.5677	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	230	77	A	D	gCc/gAc	5,13	1	0	probably_damaging	1	neutral	0,24	neutral	0,58	deleterious	-6,71	deleterious	-5,94	high_impact	4,53	damaging	0,32	damaging	0,25	deleterious	4,48	24,2	0,18	0,45	NA	NA	disease	0,91	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	-0,07	high_impact	3,14	0,39	0,8	68,72	19,49	P	0,77	P	0,94	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7815	7815	C	G	MI.5678	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	230	77	A	G	gCc/gGc	5,13	1	0	probably_damaging	0,99	neutral	0,25	neutral	0,73	deleterious	-3,06	deleterious	-3,96	medium_impact	2,81	damaging	0,29	neutral	0,38	deleterious	3,93	23,5	0,38	0,5	NA	NA	disease	0,73	disease	0,61	neutral	0,35	3	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,83	low_impact	-2,58	medium_impact	-0,06	medium_impact	1,53	0,65	0,8	68,72	19,49	P	0,92	P	0,74	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7815	7815	C	T	MI.5679	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	230	77	A	V	gCc/gTc	5,13	1	0	probably_damaging	1	neutral	0,51	neutral	0,63	deleterious	-4,63	deleterious	-3,97	medium_impact	3,38	damaging	0,25	damaging	0,2	deleterious	4,47	24,2	0,41	0,5	NA	NA	disease	0,85	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,89	low_impact	-3,52	medium_impact	0,21	high_impact	2,06	0,74	0,85	68,72	19,49	P	0,92	P	0,79	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8794	8794	C	A	MI.568	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	268	90	H	N	Cac/Aac	-20	0	0,17	possibly_damaging	0,46	deleterious	0	neutral	4,38	neutral	-0,55	deleterious	-4,88	low_impact	1,18	neutral	0,83	neutral	0,47	deleterious	2,29	18,12	0,67	0,75	disease	0,68	disease	0,54	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,58	medium_impact	-0,69	low_impact	-1,4	medium_impact	-0,09	0,63	0,9	23,45	16,35	N	0,39	N	0,75	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7817	7817	C	A	MI.5680	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	232	78	L	I	Ctc/Atc	-2,24	0	0	benign	0,18	neutral	0,44	neutral	1,39	neutral	-1,14	neutral	-1,95	low_impact	1,34	damaging	0,55	neutral	0,46	deleterious	2,2	17,51	0,47	0,55	NA	NA	disease	0,5	neutral	0,39	neutral	0,18	6	neutral	0,47	deleterious	0,63	neutral	-6	neutral	0,24	medium_impact	-0,11	medium_impact	0,15	medium_impact	0,15	0,58	0,8	67,84	18,28	N	0,39	N	0,63	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7817	7817	C	G	MI.5681	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	232	78	L	V	Ctc/Gtc	-2,24	0	0	benign	0,07	neutral	0,48	neutral	1,48	neutral	-0,51	deleterious	-2,93	medium_impact	2,04	damaging	0,48	neutral	0,33	neutral	1,48	13,22	0,48	0,55	NA	NA	disease	0,56	disease	0,55	neutral	0,22	6	neutral	0,46	deleterious	0,71	neutral	-3	neutral	0,24	medium_impact	0,33	medium_impact	0,19	medium_impact	0,81	0,5	0,8	67,84	18,28	N	0,35	N	0,66	polymorphism	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7817	7817	C	T	MI.5682	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	232	78	L	F	Ctc/Ttc	-2,24	0	0	benign	0,01	neutral	0,41	neutral	1,4	neutral	-1,09	deleterious	-3,88	low_impact	1,77	damaging	0,58	neutral	0,41	deleterious	0,71	8,89	0,48	0,55	NA	NA	neutral	0,36	neutral	0,42	neutral	0,15	7	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,2	medium_impact	1,14	medium_impact	0,12	medium_impact	0,55	0,64	0,8	67,84	18,28	N	0,39	N	0,91	polymorphism	0,95	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7818	7818	T	C	MI.5683	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	233	78	L	P	cTc/cCc	1,68	0,87	0,01	probably_damaging	0,92	neutral	0,35	neutral	1,22	deleterious	-4,77	deleterious	-6,9	high_impact	3,77	damaging	0,34	neutral	0,28	deleterious	3,82	23,4	0,18	0,45	NA	NA	disease	0,87	disease	0,76	disease	0,72	4	neutral	0,93	neutral	0,22	deleterious	2	deleterious	0,85	low_impact	-1,71	medium_impact	0,06	high_impact	2,43	0,49	0,8	67,84	18,28	P	0,62	P	0,99	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7818	7818	T	G	MI.5684	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	233	78	L	R	cTc/cGc	1,68	0,87	0,01	possibly_damaging	0,78	neutral	0,2	neutral	1,23	deleterious	-4,2	deleterious	-5,9	high_impact	4,11	damaging	0,35	damaging	0,24	deleterious	3,97	23,6	0,2	0,45	NA	NA	disease	0,89	disease	0,77	disease	0,73	5	neutral	0,87	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-1,23	medium_impact	-0,13	high_impact	2,75	0,46	0,8	67,84	18,28	P	0,66	P	0,99	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7818	7818	T	A	MI.5685	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	233	78	L	H	cTc/cAc	1,68	0,87	0,01	possibly_damaging	0,88	neutral	0,17	neutral	1,22	deleterious	-4,79	deleterious	-6,86	high_impact	4,11	damaging	0,41	neutral	0,29	deleterious	3,98	23,6	0,23	0,45	NA	NA	disease	0,79	disease	0,74	disease	0,69	4	neutral	0,94	neutral	0,15	deleterious	1	deleterious	0,78	low_impact	-1,53	medium_impact	-0,18	high_impact	2,75	0,57	0,8	67,84	18,28	P	0,59	P	0,94	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7820	7820	C	T	MI.5686	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	235	79	P	S	Cca/Tca	-20	0	0	probably_damaging	1	neutral	0,32	neutral	0,69	deleterious	-4,77	deleterious	-7,97	high_impact	4,02	damaging	0,11	damaging	0,03	deleterious	3,82	23,4	0,43	0,55	NA	NA	disease	0,85	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	0,02	high_impact	2,66	0,18	0,8	68,28	19,19	P	0,5	N	0,94	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7820	7820	C	A	MI.5687	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	235	79	P	T	Cca/Aca	-20	0	0	probably_damaging	1	neutral	0,2	neutral	0,69	deleterious	-4,83	deleterious	-7,97	high_impact	4,57	damaging	0,1	damaging	0,02	deleterious	3,61	23,2	0,28	0,45	NA	NA	disease	0,81	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	-0,13	high_impact	3,18	0,72	0,85	68,28	19,19	P	0,5	N	0,96	polymorphism	1	0,29	.	.	.	.	.	.	COSM1319392	.	.	.	.	.	.	.	.
chrM	7820	7820	C	G	MI.5688	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	235	79	P	A	Cca/Gca	-20	0	0	probably_damaging	0,99	neutral	0,41	neutral	0,71	deleterious	-4,33	deleterious	-7,97	high_impact	4,57	damaging	0,14	damaging	0,11	deleterious	3,01	22,3	0,29	0,45	NA	NA	disease	0,72	disease	0,71	disease	0,67	3	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,84	low_impact	-2,58	medium_impact	0,12	high_impact	3,18	0,62	0,8	68,28	19,19	P	0,52	P	0,9	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7821	7821	C	G	MI.5689	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	236	79	P	R	cCa/cGa	7,21	1	0	probably_damaging	1	neutral	0,13	neutral	0,68	deleterious	-5,26	deleterious	-8,96	high_impact	4,57	damaging	0,11	damaging	0,02	deleterious	3,54	23,1	0,21	0,45	NA	NA	disease	0,92	disease	0,81	disease	0,73	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	-0,25	high_impact	3,18	0,65	0,8	68,28	19,19	P	0,82	P	0,85	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8794	8794	C	T	MI.569	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	268	90	H	Y	Cac/Tac	-20	0	0,17	benign	0	neutral	1	neutral	4,68	neutral	3,37	neutral	0,24	neutral_impact	-2,38	neutral	0,96	neutral	0,89	neutral	-0,94	0,02	0,7	0,75	neutral	0,43	neutral	0,06	disease	0,52	neutral	0,21	6	neutral	0	deleterious	1	neutral	-6	neutral	0,13	high_impact	2,09	high_impact	1,98	low_impact	-3,14	0,39	0,9	23,45	16,35	N	0,44	N	0,04	polymorphism	1	0,03	rs2298007	.	.	.	.	.	COSM488775	.	14,37	C8794T	Exercise Endurance/Coronary Atherosclerosis risk	+	-	Reported	2
chrM	7821	7821	C	A	MI.5690	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	236	79	P	Q	cCa/cAa	7,21	1	0	probably_damaging	1	neutral	0,15	neutral	0,67	deleterious	-5,38	deleterious	-7,97	high_impact	4,57	damaging	0,11	damaging	0,03	deleterious	4,1	23,7	0,2	0,45	NA	NA	disease	0,87	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,21	high_impact	3,18	0,55	0,8	68,28	19,19	P	0,82	P	0,88	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7821	7821	C	T	MI.5691	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	236	79	P	L	cCa/cTa	7,21	1	0	probably_damaging	1	neutral	0,4	neutral	0,73	deleterious	-3,95	deleterious	-9,93	high_impact	4,22	damaging	0,09	damaging	0,03	deleterious	4,35	24,1	0,32	0,5	NA	NA	disease	0,92	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,11	high_impact	2,85	0,74	0,85	68,28	19,19	P	0,78	P	0,92	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7823	7823	T	A	MI.5692	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	238	80	S	T	Tcc/Acc	-12,16	0	0	benign	0,05	neutral	0,28	neutral	-0,21	deleterious	-6,35	deleterious	-2,99	high_impact	4,24	damaging	0,3	neutral	0,33	deleterious	1,87	15,38	0,38	0,5	NA	NA	disease	0,67	disease	0,7	disease	0,67	3	neutral	0,7	deleterious	0,62	neutral	-2	neutral	0,27	medium_impact	0,47	medium_impact	-0,02	high_impact	2,87	0,79	0,85	68,28	19,22	P	0,49	N	0,53	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7823	7823	T	C	MI.5693	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	238	80	S	P	Tcc/Ccc	-12,16	0	0	benign	0	neutral	0,16	neutral	-0,23	deleterious	-7,66	deleterious	-4,98	high_impact	4,58	damaging	0,31	neutral	0,31	deleterious	1,99	16,17	0,2	0,45	NA	NA	disease	0,84	disease	0,81	disease	0,7	4	neutral	0,84	deleterious	0,58	neutral	-2	neutral	0,32	high_impact	2,08	medium_impact	-0,19	high_impact	3,19	0,46	0,8	68,28	19,22	P	0,55	P	0,99	polymorphism	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7823	7823	T	G	MI.5694	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	238	80	S	A	Tcc/Gcc	-12,16	0	0	benign	0,07	neutral	0,36	neutral	-0,17	deleterious	-5,52	deleterious	-2,99	high_impact	4,58	damaging	0,32	neutral	0,39	deleterious	1,81	15,04	0,37	0,5	NA	NA	disease	0,63	disease	0,7	disease	0,67	3	neutral	0,6	deleterious	0,65	neutral	-2	neutral	0,27	medium_impact	0,33	medium_impact	0,07	high_impact	3,19	0,72	0,85	68,28	19,22	P	0,52	P	0,36	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7824	7824	C	G	MI.5695	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	239	80	S	C	tCc/tGc	7,44	1	0	possibly_damaging	0,81	neutral	0,08	neutral	-0,24	deleterious	-8,33	deleterious	-4,98	high_impact	4,58	damaging	0,3	neutral	0,3	deleterious	3,4	23	0,25	0,45	NA	NA	disease	0,76	disease	0,7	disease	0,66	3	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,75	low_impact	-1,31	medium_impact	-0,38	high_impact	3,19	0,49	0,8	68,28	19,22	P	0,7	P	0,91	disease_causing	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7824	7824	C	T	MI.5696	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	239	80	S	F	tCc/tTc	7,44	1	0	possibly_damaging	0,88	neutral	0,36	neutral	-0,24	deleterious	-8,65	deleterious	-5,98	high_impact	4,58	damaging	0,3	damaging	0,25	deleterious	4,1	23,7	0,18	0,45	NA	NA	disease	0,88	disease	0,74	disease	0,7	4	neutral	0,89	neutral	0,24	deleterious	1	deleterious	0,84	low_impact	-1,53	medium_impact	0,07	high_impact	3,19	0,33	0,8	68,28	19,22	P	0,73	P	0,99	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7824	7824	C	A	MI.5697	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	239	80	S	Y	tCc/tAc	7,44	1	0	possibly_damaging	0,88	neutral	0,35	neutral	-0,24	deleterious	-8,81	deleterious	-5,98	high_impact	4,58	damaging	0,29	damaging	0,24	deleterious	4,08	23,7	0,18	0,45	NA	NA	disease	0,85	disease	0,74	disease	0,7	4	neutral	0,89	neutral	0,24	deleterious	1	deleterious	0,82	low_impact	-1,53	medium_impact	0,06	high_impact	3,19	0,68	0,85	68,28	19,22	P	0,85	P	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7826	7826	C	A	MI.5698	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	241	81	L	M	Cta/Ata	-14,47	0	0	probably_damaging	1	neutral	0,13	neutral	0,76	deleterious	-4,43	neutral	-1,96	medium_impact	3,17	damaging	0,17	damaging	0,06	deleterious	3,72	23,3	0,34	0,5	disease	0,68	disease	0,63	disease	0,54	neutral	0,48	0	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,79	low_impact	-3,52	medium_impact	-0,25	medium_impact	1,87	0,69	0,85	67,84	19,51	P	0,61	P	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7826	7826	C	G	MI.5699	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	241	81	L	V	Cta/Gta	-14,47	0	0	probably_damaging	0,94	neutral	0,35	neutral	0,77	deleterious	-4,06	deleterious	-2,85	high_impact	3,67	damaging	0,14	damaging	0,02	deleterious	3,36	22,9	0,32	0,5	disease	0,66	disease	0,69	disease	0,55	neutral	0,48	0	neutral	0,95	neutral	0,21	deleterious	2	deleterious	0,8	low_impact	-1,83	medium_impact	0,06	high_impact	2,34	0,55	0,8	67,84	19,51	P	0,55	P	0,66	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8552	8552	T	A	MI.57	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	26	9	F	Y	tTc/tAc	7,53	1	0	probably_damaging	0,92	deleterious	0,02	neutral	3,95	neutral	-1,79	deleterious	-2,53	medium_impact	2,9	damaging	0,59	neutral	0,54	deleterious	4,05	23,7	0,35	0,65	disease	0,81	disease	0,75	disease	0,82	disease	0,84	7	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,8	low_impact	-1,76	medium_impact	-0,66	medium_impact	1,39	0,46	0,9	49,56	8,77	P	0,64	P	0,89	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8794	8794	C	G	MI.570	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	268	90	H	D	Cac/Gac	-20	0	0,17	possibly_damaging	0,56	deleterious	0	neutral	4,37	neutral	-1,32	deleterious	-6,2	low_impact	1,1	neutral	0,81	neutral	0,39	deleterious	3,47	23,1	0,32	0,65	disease	0,78	disease	0,55	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,67	medium_impact	-0,86	low_impact	-1,4	medium_impact	-0,16	0,61	0,9	23,45	16,35	N	0,35	N	0,9	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7827	7827	T	A	MI.5700	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	242	81	L	Q	cTa/cAa	-0,86	0	0	probably_damaging	1	neutral	0,23	neutral	0,71	deleterious	-6,88	deleterious	-5,94	high_impact	4,37	damaging	0,14	damaging	0,02	deleterious	4	23,6	0,2	0,45	disease	0,92	disease	0,81	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	-0,09	high_impact	2,99	0,67	0,85	67,84	19,51	P	0,74	P	0,95	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7827	7827	T	C	MI.5701	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	242	81	L	P	cTa/cCa	-0,86	0	0	probably_damaging	1	neutral	0,34	neutral	0,71	deleterious	-7,46	deleterious	-6,91	high_impact	4,37	damaging	0,14	damaging	0,02	deleterious	3,85	23,4	0,17	0,45	disease	0,94	disease	0,84	disease	0,77	disease	0,67	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	0,05	high_impact	2,99	0,49	0,8	67,84	19,51	P	0,72	P	0,99	polymorphism	0,92	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7827	7827	T	G	MI.5702	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	242	81	L	R	cTa/cGa	-0,86	0	0	probably_damaging	1	neutral	0,19	neutral	0,71	deleterious	-6,99	deleterious	-5,94	high_impact	4,37	damaging	0,16	damaging	0,01	deleterious	4,15	23,8	0,16	0,45	disease	0,93	disease	0,9	disease	0,75	disease	0,63	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	-0,14	high_impact	2,99	0,56	0,8	67,84	19,51	P	0,77	P	0,99	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7829	7829	C	A	MI.5703	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	244	82	R	S	Cgc/Agc	-2,48	0	0	probably_damaging	0,98	neutral	0,79	neutral	1,52	neutral	-0,73	deleterious	-5,59	medium_impact	2,87	damaging	0,44	damaging	0,22	deleterious	4,51	24,3	0,24	0,45	neutral	0,25	disease	0,86	disease	0,67	disease	0,68	4	neutral	0,98	neutral	0,41	deleterious	1	deleterious	0,76	low_impact	-2,3	medium_impact	0,52	medium_impact	1,59	0,42	0,8	68,72	19,03	N	0,35	N	0,77	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7829	7829	C	T	MI.5704	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	244	82	R	C	Cgc/Tgc	-2,48	0	0	probably_damaging	1	neutral	0,06	neutral	1,4	deleterious	-4,94	deleterious	-7,66	high_impact	4,14	damaging	0,37	damaging	0,12	deleterious	4,95	25	0,26	0,45	disease	0,79	disease	0,87	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	-0,46	high_impact	2,78	0,72	0,85	68,72	19,03	P	0,52	P	1	polymorphism	0,88	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7829	7829	C	G	MI.5705	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	244	82	R	G	Cgc/Ggc	-2,48	0	0	probably_damaging	0,98	neutral	0,39	neutral	1,44	neutral	-1,67	deleterious	-6,66	high_impact	4,14	damaging	0,4	damaging	0,24	deleterious	4,16	23,8	0,24	0,45	neutral	0,46	disease	0,82	disease	0,72	disease	0,68	4	deleterious	0,98	neutral	0,21	deleterious	2	deleterious	0,76	low_impact	-2,3	medium_impact	0,1	high_impact	2,78	0,56	0,8	68,72	19,03	P	0,53	P	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7830	7830	G	C	MI.5706	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	245	82	R	P	cGc/cCc	2,37	0,74	0,01	probably_damaging	0,99	neutral	0,3	neutral	1,45	neutral	-2,47	deleterious	-6,58	medium_impact	3,1	damaging	0,36	damaging	0,14	deleterious	4,19	23,8	0,11	0,4	disease	0,54	disease	0,91	disease	0,81	disease	0,73	5	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,85	low_impact	-2,58	medium_impact	0	medium_impact	1,8	0,46	0,8	68,72	19,03	P	0,64	P	1	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7830	7830	G	T	MI.5707	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	245	82	R	L	cGc/cTc	2,37	0,74	0,01	probably_damaging	0,96	neutral	0,39	neutral	1,44	neutral	-2,33	deleterious	-6,66	medium_impact	3,17	damaging	0,41	damaging	0,25	deleterious	4,25	23,9	0,36	0,5	neutral	0,46	disease	0,93	disease	0,67	disease	0,71	4	neutral	0,96	neutral	0,22	deleterious	1	deleterious	0,8	low_impact	-2,01	medium_impact	0,1	medium_impact	1,87	0,37	0,8	68,72	19,03	P	0,55	P	1	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7830	7830	G	A	MI.5708	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	245	82	R	H	cGc/cAc	2,37	0,74	0,01	probably_damaging	0,99	neutral	0,15	neutral	1,44	neutral	-2,07	deleterious	-4,66	low_impact	1,82	damaging	0,47	damaging	0,18	deleterious	4,38	24,1	0,45	0,55	neutral	0,43	disease	0,79	neutral	0,47	neutral	0,16	7	deleterious	0,99	neutral	0,08	neutral	-2	deleterious	0,78	low_impact	-2,58	medium_impact	-0,21	medium_impact	0,6	0,82	0,85	68,72	19,03	N	0,39	N	0,99	disease_causing	1	0,1	rs878897170	.	.	.	.	.	COSM488769	.	.	.	.	.	.	.	.
chrM	7832	7832	A	G	MI.5709	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	247	83	I	V	Atc/Gtc	-2,01	0	0	benign	0,01	neutral	0,06	neutral	1,48	neutral	-0,55	neutral	-0,72	medium_impact	2,3	neutral	0,63	neutral	0,56	neutral	1,07	11,05	0,68	0,7	neutral	0,34	neutral	0,48	neutral	0,38	neutral	0,3	4	neutral	0,94	deleterious	0,53	neutral	-3	neutral	0,18	medium_impact	1,14	medium_impact	-0,46	medium_impact	1,05	0,49	0,8	68,28	19,24	N	0,51	P	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8795	8795	A	T	MI.571	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	269	90	H	L	cAc/cTc	1,52	0,91	0	benign	0,16	deleterious	0,01	neutral	4,51	neutral	2,21	deleterious	-5,94	neutral_impact	0,57	neutral	0,86	neutral	0,43	deleterious	1,96	15,96	0,41	0,65	neutral	0,27	disease	0,52	disease	0,76	disease	0,71	4	deleterious	0,99	neutral	0,43	neutral	-2	neutral	0,35	medium_impact	-0,07	medium_impact	-0,84	medium_impact	-0,61	0,29	0,9	23,45	16,35	N	0,33	N	0,91	polymorphism	0,92	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7832	7832	A	T	MI.5710	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	247	83	I	F	Atc/Ttc	-2,01	0	0	possibly_damaging	0,85	neutral	0,16	neutral	1,27	deleterious	-3,34	deleterious	-3,8	medium_impact	3,4	damaging	0,5	damaging	0,24	deleterious	3,72	23,3	0,47	0,55	disease	0,53	disease	0,8	disease	0,57	disease	0,69	4	neutral	0,92	neutral	0,16	NA	0	deleterious	0,77	low_impact	-1,42	medium_impact	-0,19	high_impact	2,08	0,71	0,85	68,28	19,24	N	0,35	N	0,92	polymorphism	0,98	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7832	7832	A	C	MI.5711	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	247	83	I	L	Atc/Ctc	-2,01	0	0	benign	0,21	neutral	1	neutral	2,06	neutral	1,47	neutral	-1,65	neutral_impact	-0,02	damaging	0,59	neutral	0,47	deleterious	0,46	7,12	0,44	0,55	neutral	0,19	neutral	0,21	neutral	0,26	neutral	0,35	3	neutral	0,21	deleterious	0,9	neutral	-6	neutral	0,16	medium_impact	-0,18	high_impact	1,86	low_impact	-1,12	0,59	0,8	68,28	19,24	N	0,32	N	0,7	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7833	7833	T	A	MI.5712	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	248	83	I	N	aTc/aAc	6,98	1	0	probably_damaging	1	deleterious	0,04	neutral	1,23	deleterious	-5,89	deleterious	-6,63	medium_impact	3,4	damaging	0,44	damaging	0,23	deleterious	4,42	24,2	0,38	0,5	disease	0,64	disease	0,87	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,84	low_impact	-3,52	medium_impact	-0,56	high_impact	2,08	0,49	0,8	68,28	19,24	P	0,59	P	0,99	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7833	7833	T	C	MI.5713	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	248	83	I	T	aTc/aCc	6,98	1	0	probably_damaging	0,97	neutral	0,07	neutral	1,25	deleterious	-3,88	deleterious	-4,49	medium_impact	2,22	damaging	0,55	neutral	0,54	deleterious	3,29	22,8	0,6	0,65	neutral	0,46	disease	0,67	neutral	0,42	neutral	0,34	3	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,67	low_impact	-2,13	medium_impact	-0,42	medium_impact	0,98	0,47	0,8	68,28	19,24	P	0,52	P	0,96	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7833	7833	T	G	MI.5714	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	248	83	I	S	aTc/aGc	6,98	1	0	probably_damaging	0,99	neutral	0,25	neutral	1,24	deleterious	-4,81	deleterious	-5,64	medium_impact	2,54	damaging	0,49	neutral	0,32	deleterious	4,26	23,9	0,37	0,5	neutral	0,49	disease	0,85	disease	0,65	disease	0,61	2	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,79	low_impact	-2,58	medium_impact	-0,06	medium_impact	1,28	0,44	0,8	68,28	19,24	N	0,48	N	0,91	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7834	7834	C	A	MI.5715	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	249	83	I	M	atC/atA	4,67	1	0	probably_damaging	0,93	neutral	0,05	neutral	1,28	neutral	-2,97	deleterious	-2,59	medium_impact	3,05	damaging	0,51	neutral	0,35	deleterious	3,8	23,4	0,61	0,65	disease	0,53	disease	0,65	disease	0,56	disease	0,66	3	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,54	low_impact	-1,77	medium_impact	-0,5	medium_impact	1,75	0,73	0,85	68,28	19,24	P	0,54	P	0,77	disease_causing	0,97	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7834	7834	C	G	MI.5716	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	249	83	I	M	atC/atG	4,67	1	0	probably_damaging	0,93	neutral	0,05	neutral	1,28	neutral	-2,97	deleterious	-2,59	medium_impact	3,05	damaging	0,51	neutral	0,35	deleterious	3,33	22,9	0,61	0,65	disease	0,53	disease	0,65	disease	0,56	disease	0,66	3	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,54	low_impact	-1,77	medium_impact	-0,5	medium_impact	1,75	0,73	0,85	68,28	19,24	P	0,54	P	0,77	disease_causing	0,97	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7835	7835	C	G	MI.5717	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	250	84	L	V	Ctt/Gtt	-4,78	0	0	probably_damaging	0,97	deleterious	0,04	neutral	0,74	deleterious	-3,51	deleterious	-2,99	high_impact	3,94	damaging	0,27	damaging	0,27	deleterious	3,37	22,9	0,42	0,55	disease	0,5	disease	0,66	disease	0,7	disease	0,67	3	deleterious	0,99	neutral	0,04	deleterious	6	deleterious	0,72	low_impact	-2,13	medium_impact	-0,56	high_impact	2,59	0,75	0,85	68,72	19,53	P	0,81	P	0,63	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7835	7835	C	T	MI.5718	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	250	84	L	F	Ctt/Ttt	-4,78	0	0	probably_damaging	1	neutral	0,14	neutral	0,68	deleterious	-4,54	deleterious	-3,98	high_impact	4,41	damaging	0,3	neutral	0,28	deleterious	3,91	23,5	0,4	0,5	disease	0,54	disease	0,71	disease	0,58	disease	0,64	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,76	low_impact	-3,52	medium_impact	-0,23	high_impact	3,03	0,67	0,85	68,72	19,53	P	0,6	P	0,91	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7835	7835	C	A	MI.5719	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	250	84	L	I	Ctt/Att	-4,78	0	0	probably_damaging	0,99	neutral	0,33	neutral	0,75	deleterious	-3,45	neutral	-1,99	medium_impact	3,14	damaging	0,28	neutral	0,42	deleterious	4,08	23,7	0,42	0,55	disease	0,54	disease	0,59	disease	0,51	neutral	0,22	6	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,72	low_impact	-2,58	medium_impact	0,04	medium_impact	1,84	0,72	0,85	68,72	19,53	P	0,85	P	0,6	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8795	8795	A	C	MI.572	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	269	90	H	P	cAc/cCc	1,52	0,91	0	possibly_damaging	0,78	deleterious	0	neutral	4,38	neutral	-0,96	deleterious	-6,63	medium_impact	2,07	neutral	0,74	neutral	0,32	deleterious	2,96	22,1	0,34	0,65	disease	0,73	disease	0,76	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	4	deleterious	0,77	low_impact	-1,28	low_impact	-1,4	medium_impact	0,68	0,42	0,9	23,45	16,35	N	0,27	N	0,96	polymorphism	0,92	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7836	7836	T	A	MI.5720	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	251	84	L	H	cTt/cAt	0,98	0,43	0	probably_damaging	1	neutral	0,12	neutral	0,64	deleterious	-6,32	deleterious	-6,97	high_impact	4,75	damaging	0,28	damaging	0,25	deleterious	4,03	23,6	0,17	0,45	disease	0,83	disease	0,82	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	-0,27	high_impact	3,35	0,64	0,8	68,72	19,53	P	0,89	P	0,94	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7836	7836	T	C	MI.5721	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	251	84	L	P	cTt/cCt	0,98	0,43	0	probably_damaging	1	deleterious	0,02	neutral	0,65	deleterious	-6,1	deleterious	-6,97	high_impact	4,75	damaging	0,29	damaging	0,25	deleterious	3,73	23,3	0,12	0,4	disease	0,83	disease	0,81	disease	0,81	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-3,52	medium_impact	-0,73	high_impact	3,35	0,49	0,8	68,72	19,53	P	0,88	P	0,99	polymorphism	0,64	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7836	7836	T	G	MI.5722	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	251	84	L	R	cTt/cGt	0,98	0,43	0	probably_damaging	1	neutral	0,05	neutral	0,65	deleterious	-5,58	deleterious	-5,97	high_impact	4,75	damaging	0,27	damaging	0,2	deleterious	4,07	23,7	0,13	0,4	disease	0,75	disease	0,89	disease	0,81	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,5	high_impact	3,35	0,54	0,8	68,72	19,53	P	0,9	P	0,99	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7838	7838	T	A	MI.5723	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	253	85	Y	N	Tac/Aac	-16,08	0	0	probably_damaging	0,99	deleterious	0,03	neutral	1,12	deleterious	-4,2	deleterious	-8,96	high_impact	4,37	damaging	0,29	neutral	0,31	deleterious	3,93	23,5	0,4	0,5	disease	0,65	disease	0,86	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-2,58	medium_impact	-0,63	high_impact	2,99	0,17	0,8	68,28	19,5	P	0,73	P	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7838	7838	T	G	MI.5724	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	253	85	Y	D	Tac/Gac	-16,08	0	0	probably_damaging	0,99	deleterious	0,02	neutral	1,12	deleterious	-4,05	deleterious	-9,96	high_impact	4,71	damaging	0,3	damaging	0,28	deleterious	3,85	23,4	0,25	0,45	disease	0,69	disease	0,89	disease	0,85	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,81	low_impact	-2,58	medium_impact	-0,73	high_impact	3,31	0,27	0,8	68,28	19,5	P	0,66	P	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7838	7838	T	C	MI.5725	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	253	85	Y	H	Tac/Cac	-16,08	0	0	probably_damaging	0,99	neutral	0,06	neutral	1,11	deleterious	-4,24	deleterious	-4,98	high_impact	4,16	damaging	0,27	neutral	0,28	deleterious	3,47	23	0,55	0,6	disease	0,73	disease	0,84	disease	0,84	disease	0,74	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,81	low_impact	-2,58	medium_impact	-0,46	high_impact	2,8	0,31	0,8	68,28	19,5	P	0,81	P	0,94	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7839	7839	A	G	MI.5726	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	254	85	Y	C	tAc/tGc	7,44	1	0	probably_damaging	1	deleterious	0,02	neutral	1,1	deleterious	-5,2	deleterious	-8,96	high_impact	4,37	damaging	0,26	damaging	0,24	deleterious	3,49	23,1	0,38	0,5	disease	0,84	disease	0,86	disease	0,81	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,52	medium_impact	-0,73	high_impact	2,99	0,11	0,8	68,28	19,5	P	0,9	P	0,96	disease_causing	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7839	7839	A	T	MI.5727	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	254	85	Y	F	tAc/tTc	7,44	1	0	probably_damaging	0,92	neutral	0,08	neutral	1,18	neutral	-2,58	deleterious	-3,98	medium_impact	2,66	damaging	0,29	neutral	0,29	deleterious	3,29	22,8	0,47	0,55	neutral	0,31	disease	0,81	disease	0,66	disease	0,66	3	neutral	0,98	neutral	0,08	deleterious	1	deleterious	0,71	low_impact	-1,71	medium_impact	-0,38	medium_impact	1,39	0,36	0,8	68,28	19,5	P	0,88	P	0,87	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7839	7839	A	C	MI.5728	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	254	85	Y	S	tAc/tCc	7,44	1	0	probably_damaging	0,99	neutral	0,1	neutral	1,14	deleterious	-3,43	deleterious	-8,96	high_impact	4,37	damaging	0,27	neutral	0,39	deleterious	3,67	23,3	0,29	0,45	neutral	0,36	disease	0,88	disease	0,78	disease	0,69	4	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,78	low_impact	-2,58	medium_impact	-0,32	high_impact	2,99	0,23	0,8	68,28	19,5	P	0,91	P	0,99	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7841	7841	A	C	MI.5729	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	256	86	M	L	Ata/Cta	-4,09	0	0	benign	0	neutral	1	neutral	1,84	neutral	2,24	neutral	0,66	neutral_impact	-0,7	neutral	0,81	neutral	0,93	neutral	-1,44	0	0,6	0,65	neutral	0,32	neutral	0,19	neutral	0,21	neutral	0,36	3	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,08	high_impact	1,86	low_impact	-1,76	0,55	0,8	27,75	43,33	N	0,33	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8795	8795	A	G	MI.573	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	269	90	H	R	cAc/cGc	1,52	0,91	0	benign	0,38	deleterious	0	neutral	4,39	neutral	-0,31	deleterious	-5,28	low_impact	1,73	neutral	0,81	neutral	0,4	neutral	1,32	12,35	0,61	0,7	disease	0,65	disease	0,6	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,58	medium_impact	-0,55	low_impact	-1,4	medium_impact	0,39	0,46	0,9	23,45	16,35	N	0,32	N	0,86	polymorphism	0,98	0,18	.	.	.	.	.	.	.	.	.	A8795G	MILS protective factor	-	+	Reported	1
chrM	7841	7841	A	G	MI.5730	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	256	86	M	V	Ata/Gta	-4,09	0	0	benign	0	neutral	0,12	neutral	1,61	neutral	0,41	neutral	-1,66	low_impact	1,84	neutral	0,68	neutral	0,46	deleterious	0,72	8,94	0,62	0,65	neutral	0,26	disease	0,57	disease	0,53	disease	0,59	2	neutral	0,88	deleterious	0,56	neutral	-6	neutral	0,14	high_impact	2,08	medium_impact	-0,27	medium_impact	0,62	0,41	0,8	27,75	43,33	N	0,45	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7841	7841	A	T	MI.5731	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	256	86	M	L	Ata/Tta	-4,09	0	0	benign	0	neutral	1	neutral	1,84	neutral	2,24	neutral	0,66	neutral_impact	-0,7	neutral	0,81	neutral	0,93	neutral	-1,41	0	0,6	0,65	neutral	0,32	neutral	0,19	neutral	0,21	neutral	0,36	3	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,08	high_impact	1,86	low_impact	-1,76	0,55	0,8	27,75	43,33	N	0,33	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7842	7842	T	A	MI.5732	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	257	86	M	K	aTa/aAa	0,75	0,11	0	benign	0	neutral	0,12	neutral	1,59	neutral	0,16	deleterious	-4,5	low_impact	1,56	damaging	0,58	neutral	0,38	deleterious	2,09	16,78	0,3	0,45	neutral	0,29	disease	0,73	disease	0,74	disease	0,7	4	neutral	0,88	deleterious	0,56	neutral	-6	neutral	0,2	high_impact	2,08	medium_impact	-0,27	medium_impact	0,36	0,55	0,8	27,75	43,33	N	0,41	N	0,96	polymorphism	0,92	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7842	7842	T	C	MI.5733	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	257	86	M	T	aTa/aCa	0,75	0,11	0	benign	0	neutral	0,07	neutral	1,58	neutral	-0,08	deleterious	-3,73	medium_impact	2,03	neutral	0,66	neutral	0,48	neutral	1,02	10,77	0,51	0,6	neutral	0,34	disease	0,54	disease	0,56	disease	0,65	3	neutral	0,93	deleterious	0,54	neutral	-3	neutral	0,17	high_impact	2,08	medium_impact	-0,42	medium_impact	0,8	0,19	0,8	27,75	43,33	N	0,49	N	0,85	polymorphism	0,99	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7843	7843	A	C	MI.5734	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	258	86	M	I	atA/atC	7,44	0,97	0	benign	0	neutral	0,2	neutral	1,6	neutral	0,31	neutral	-0,93	neutral_impact	0,5	neutral	0,74	neutral	0,59	neutral	1,48	13,19	0,59	0,65	neutral	0,3	neutral	0,47	neutral	0,32	neutral	0,34	3	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,15	high_impact	2,08	medium_impact	-0,13	medium_impact	-0,64	0,55	0,8	27,75	43,33	P	0,59	P	0,53	polymorphism	0,66	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7843	7843	A	T	MI.5735	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	258	86	M	I	atA/atT	7,44	0,97	0	benign	0	neutral	0,2	neutral	1,6	neutral	0,31	neutral	-0,93	neutral_impact	0,5	neutral	0,74	neutral	0,59	neutral	1,51	13,36	0,59	0,65	neutral	0,3	neutral	0,47	neutral	0,32	neutral	0,34	3	neutral	0,8	deleterious	0,6	neutral	-6	neutral	0,15	high_impact	2,08	medium_impact	-0,13	medium_impact	-0,64	0,55	0,8	27,75	43,33	P	0,57	P	0,53	polymorphism	0,66	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7844	7844	A	T	MI.5736	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	259	87	T	S	Aca/Tca	-1,09	0	0	benign	0,12	neutral	0,17	neutral	1,58	neutral	-0,09	neutral	-0,51	low_impact	1,08	neutral	0,69	neutral	0,72	neutral	1,31	12,32	0,46	0,55	neutral	0,34	neutral	0,31	neutral	0,33	neutral	0,45	1	neutral	0,81	deleterious	0,53	neutral	-6	neutral	0,22	medium_impact	0,09	medium_impact	-0,18	medium_impact	-0,09	0,59	0,8	29,52	66,93	N	0,51	P	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7844	7844	A	C	MI.5737	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	259	87	T	P	Aca/Cca	-1,09	0	0	benign	0,41	neutral	0,05	neutral	1,52	neutral	-1,56	neutral	-1,64	medium_impact	2,94	neutral	0,6	neutral	0,44	deleterious	1,81	15,05	0,17	0,45	disease	0,71	disease	0,71	disease	0,67	disease	0,69	4	neutral	0,94	neutral	0,32	neutral	-3	deleterious	0,64	medium_impact	-0,57	medium_impact	-0,5	medium_impact	1,65	0,51	0,8	29,52	66,93	N	0,34	N	0,62	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7844	7844	A	G	MI.5738	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	259	87	T	A	Aca/Gca	-1,09	0	0	benign	0,01	neutral	0,13	neutral	1,57	neutral	-0,27	neutral	-0,64	medium_impact	2,04	neutral	0,85	neutral	0,82	neutral	1,53	13,48	0,56	0,6	neutral	0,4	neutral	0,26	disease	0,53	neutral	0,46	1	neutral	0,87	deleterious	0,56	neutral	-3	neutral	0,14	medium_impact	1,14	medium_impact	-0,25	medium_impact	0,81	0,24	0,8	29,52	66,93	N	0,45	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7845	7845	C	A	MI.5739	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	260	87	T	K	aCa/aAa	8,59	1	0	benign	0,17	neutral	0,22	neutral	1,54	neutral	-1,09	neutral	-0,77	medium_impact	2,6	neutral	0,66	neutral	0,58	deleterious	2,67	20,6	0,31	0,45	neutral	0,37	disease	0,53	disease	0,63	disease	0,67	3	neutral	0,74	deleterious	0,53	neutral	-3	neutral	0,36	medium_impact	-0,08	medium_impact	-0,1	medium_impact	1,33	0,58	0,8	29,52	66,93	P	0,62	P	0,48	disease_causing	0,53	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8796	8796	C	A	MI.574	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	270	90	H	Q	caC/caA	6,84	0,98	0	possibly_damaging	0,6	deleterious	0	neutral	4,38	neutral	-0,43	deleterious	-4,75	medium_impact	2,07	neutral	0,85	neutral	0,4	deleterious	3,38	22,9	0,69	0,75	disease	0,67	neutral	0,41	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	4	deleterious	0,57	medium_impact	-0,92	low_impact	-1,4	medium_impact	0,68	0,63	0,9	23,45	16,35	P	0,55	P	0,76	polymorphism	0,82	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7845	7845	C	T	MI.5740	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	260	87	T	M	aCa/aTa	8,59	1	0	possibly_damaging	0,76	neutral	0,62	neutral	1,69	neutral	1,13	neutral	4,42	neutral_impact	-1,04	neutral	0,73	neutral	0,96	neutral	1,04	10,9	0,44	0,55	neutral	0,25	neutral	0,06	neutral	0,15	neutral	0,2	6	neutral	0,71	neutral	0,43	neutral	-3	deleterious	0,5	low_impact	-1,19	medium_impact	0,32	low_impact	-2,08	0,55	0,8	29,52	66,93	P	0,56	P	0,03	polymorphism	0,61	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7847	7847	G	T	MI.5741	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	262	88	D	Y	Gac/Tac	-0,17	0,7	0	probably_damaging	1	neutral	1	neutral	1,17	deleterious	-3,64	deleterious	-8,96	medium_impact	3,29	damaging	0,17	damaging	0,03	deleterious	3,85	23,4	0,28	0,45	disease	0,79	disease	0,89	disease	0,74	disease	0,67	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,88	low_impact	-3,52	high_impact	1,86	medium_impact	1,98	0,24	0,8	68,72	19,54	P	0,62	P	0,99	disease_causing	0,98	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7847	7847	G	A	MI.5742	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	262	88	D	N	Gac/Aac	-0,17	0,7	0	probably_damaging	0,98	neutral	0,25	neutral	1,22	neutral	-2,44	deleterious	-4,97	medium_impact	2,59	damaging	0,16	damaging	0,02	deleterious	4,17	23,8	0,75	0,8	disease	0,55	disease	0,77	disease	0,56	disease	0,64	3	deleterious	0,98	neutral	0,14	deleterious	1	deleterious	0,8	low_impact	-2,3	medium_impact	-0,06	medium_impact	1,32	0,63	0,8	68,72	19,54	P	0,84	P	0,99	disease_causing	0,86	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7847	7847	G	C	MI.5743	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	262	88	D	H	Gac/Cac	-0,17	0,7	0	probably_damaging	1	neutral	0,43	neutral	1,16	deleterious	-4,12	deleterious	-6,97	high_impact	3,72	damaging	0,13	damaging	0,02	deleterious	3,63	23,2	0,44	0,55	neutral	0,44	disease	0,84	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	0,14	high_impact	2,38	0,39	0,8	68,72	19,54	P	0,75	P	0,98	disease_causing	0,97	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7848	7848	A	T	MI.5744	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	263	88	D	V	gAc/gTc	7,44	1	0	probably_damaging	1	neutral	0,69	neutral	1,14	deleterious	-5,18	deleterious	-8,96	high_impact	3,84	damaging	0,13	damaging	0,01	deleterious	3,71	23,3	0,36	0,5	disease	0,68	disease	0,9	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	0,4	high_impact	2,5	0,21	0,8	68,72	19,54	P	0,75	P	0,99	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7848	7848	A	C	MI.5745	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	263	88	D	A	gAc/gCc	7,44	1	0	probably_damaging	0,99	neutral	0,55	neutral	1,19	neutral	-2,94	deleterious	-7,96	high_impact	4,53	damaging	0,25	damaging	0,11	deleterious	3,61	23,2	0,42	0,55	neutral	0,49	disease	0,8	disease	0,7	disease	0,68	4	deleterious	0,99	neutral	0,28	deleterious	2	deleterious	0,8	low_impact	-2,58	medium_impact	0,25	high_impact	3,14	0,44	0,8	68,72	19,54	P	0,79	P	0,97	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7848	7848	A	G	MI.5746	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	263	88	D	G	gAc/gGc	7,44	1	0	probably_damaging	0,99	neutral	0,26	neutral	1,24	neutral	-2,18	deleterious	-6,97	medium_impact	3,48	damaging	0,14	damaging	0,04	deleterious	3,95	23,6	0,4	0,5	disease	0,57	disease	0,84	disease	0,7	disease	0,7	4	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,8	low_impact	-2,58	medium_impact	-0,05	high_impact	2,16	0,33	0,8	68,72	19,54	P	0,87	P	0,97	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7849	7849	C	G	MI.5747	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	264	88	D	E	gaC/gaG	6,98	1	0	possibly_damaging	0,9	neutral	0,42	neutral	1,38	neutral	-0,95	deleterious	-3,98	low_impact	1,63	damaging	0,17	damaging	0,05	deleterious	3,8	23,4	0,57	0,65	neutral	0,35	disease	0,71	neutral	0,33	neutral	0,17	7	neutral	0,9	neutral	0,26	neutral	-3	deleterious	0,74	low_impact	-1,61	medium_impact	0,13	medium_impact	0,42	0,53	0,8	68,72	19,54	P	0,84	P	0,95	disease_causing	1	0,12	rs386829015	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7849	7849	C	A	MI.5748	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	264	88	D	E	gaC/gaA	6,98	1	0	possibly_damaging	0,9	neutral	0,42	neutral	1,38	neutral	-0,95	deleterious	-3,98	low_impact	1,63	damaging	0,17	damaging	0,05	deleterious	4,14	23,8	0,57	0,65	neutral	0,35	disease	0,71	neutral	0,33	neutral	0,17	7	neutral	0,9	neutral	0,26	neutral	-3	deleterious	0,74	low_impact	-1,61	medium_impact	0,13	medium_impact	0,42	0,53	0,8	68,72	19,54	P	0,84	P	0,95	disease_causing	1	0,12	rs386829015	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7850	7850	G	A	MI.5749	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	265	89	E	K	Gag/Aag	-3,17	0	0	probably_damaging	0,9	neutral	0,35	neutral	0,76	deleterious	-4,34	deleterious	-3,98	high_impact	3,86	damaging	0,28	damaging	0,17	deleterious	4,46	24,2	0,48	0,55	neutral	0,35	disease	0,86	disease	0,74	disease	0,69	4	neutral	0,91	neutral	0,23	deleterious	2	deleterious	0,77	low_impact	-1,61	medium_impact	0,06	high_impact	2,51	0,68	0,85	68,28	19,18	P	0,74	P	0,99	disease_causing	0,89	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8796	8796	C	G	MI.575	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	270	90	H	Q	caC/caG	6,84	0,98	0	possibly_damaging	0,6	deleterious	0	neutral	4,38	neutral	-0,43	deleterious	-4,75	medium_impact	2,07	neutral	0,85	neutral	0,4	deleterious	3,16	22,6	0,69	0,75	disease	0,67	neutral	0,41	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	4	deleterious	0,57	medium_impact	-0,92	low_impact	-1,4	medium_impact	0,68	0,63	0,9	23,45	16,35	P	0,55	P	0,76	polymorphism	0,82	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7850	7850	G	C	MI.5750	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	265	89	E	Q	Gag/Cag	-3,17	0	0	probably_damaging	0,91	neutral	0,33	neutral	0,75	deleterious	-4,47	deleterious	-2,98	high_impact	4,11	damaging	0,27	neutral	0,37	deleterious	3,35	22,9	0,55	0,6	disease	0,52	disease	0,74	disease	0,69	disease	0,66	3	neutral	0,92	neutral	0,21	deleterious	2	deleterious	0,76	low_impact	-1,66	medium_impact	0,04	high_impact	2,75	0,77	0,85	68,28	19,18	P	0,83	P	0,75	disease_causing	0,65	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7851	7851	A	C	MI.5751	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	266	89	E	A	gAg/gCg	4,21	1	0	probably_damaging	0,93	neutral	0,57	neutral	0,75	deleterious	-4,53	deleterious	-5,96	high_impact	4,31	damaging	0,29	neutral	0,36	deleterious	3,71	23,3	0,44	0,55	neutral	0,45	disease	0,71	disease	0,69	disease	0,66	3	neutral	0,92	neutral	0,32	deleterious	2	deleterious	0,74	low_impact	-1,77	medium_impact	0,27	high_impact	2,94	0,7	0,85	68,28	19,18	P	0,85	P	0,67	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7851	7851	A	T	MI.5752	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	266	89	E	V	gAg/gTg	4,21	1	0	probably_damaging	0,94	neutral	0,49	neutral	0,71	deleterious	-6,29	deleterious	-6,96	high_impact	3,68	damaging	0,26	damaging	0,28	deleterious	4,27	24	0,36	0,5	disease	0,7	disease	0,87	disease	0,71	disease	0,69	4	neutral	0,94	neutral	0,28	deleterious	2	deleterious	0,82	low_impact	-1,83	medium_impact	0,2	high_impact	2,35	0,71	0,85	68,28	19,18	P	0,86	P	0,82	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7851	7851	A	G	MI.5753	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	266	89	E	G	gAg/gGg	4,21	1	0	probably_damaging	0,96	neutral	0,37	neutral	0,73	deleterious	-5,32	deleterious	-6,96	high_impact	3,76	damaging	0,24	neutral	0,43	deleterious	4,29	24	0,49	0,55	disease	0,6	disease	0,78	disease	0,72	disease	0,67	3	neutral	0,96	neutral	0,21	deleterious	2	deleterious	0,78	low_impact	-2,01	medium_impact	0,08	high_impact	2,42	0,55	0,8	68,28	19,18	P	0,9	P	0,64	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7852	7852	G	T	MI.5754	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	267	89	E	D	gaG/gaT	6,98	1	0	possibly_damaging	0,69	neutral	0,26	neutral	1,07	neutral	-1,52	deleterious	-2,98	medium_impact	2,48	damaging	0,29	neutral	0,3	deleterious	3,75	23,3	0,58	0,65	neutral	0,45	disease	0,69	disease	0,51	neutral	0,13	7	neutral	0,79	neutral	0,29	NA	0	deleterious	0,6	low_impact	-1,04	medium_impact	-0,05	medium_impact	1,22	0,81	0,85	68,28	19,18	P	0,91	P	0,82	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7852	7852	G	C	MI.5755	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	267	89	E	D	gaG/gaC	6,98	1	0	possibly_damaging	0,69	neutral	0,26	neutral	1,07	neutral	-1,52	deleterious	-2,98	medium_impact	2,48	damaging	0,29	neutral	0,3	deleterious	3,59	23,2	0,58	0,65	neutral	0,45	disease	0,69	disease	0,51	neutral	0,13	7	neutral	0,79	neutral	0,29	NA	0	deleterious	0,6	low_impact	-1,04	medium_impact	-0,05	medium_impact	1,22	0,81	0,85	68,28	19,18	P	0,91	P	0,82	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7853	7853	G	C	MI.5756	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	268	90	V	L	Gtc/Ctc	-0,17	0,28	0,11	benign	0,01	neutral	0,8	neutral	1,31	neutral	-1,69	neutral	-1,14	low_impact	1,42	neutral	0,71	neutral	0,68	deleterious	0,55	7,8	0,61	0,65	neutral	0,45	disease	0,61	neutral	0,23	neutral	0,2	6	neutral	0,18	deleterious	0,9	neutral	-6	neutral	0,17	medium_impact	1,14	medium_impact	0,54	medium_impact	0,23	0,66	0,8	25,11	28,78	N	0,29	N	0,46	polymorphism	1	0,02	rs386420037	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7853	7853	G	T	MI.5757	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	268	90	V	F	Gtc/Ttc	-0,17	0,28	0,11	benign	0,15	neutral	0,46	neutral	1,21	deleterious	-3,54	deleterious	-2,86	low_impact	1,52	neutral	0,69	neutral	0,71	deleterious	1,96	15,95	0,21	0,45	disease	0,65	disease	0,8	neutral	0,45	disease	0,55	1	neutral	0,45	deleterious	0,66	neutral	-6	neutral	0,41	medium_impact	-0,02	medium_impact	0,17	medium_impact	0,32	0,57	0,8	25,11	28,78	N	0,25	N	0,72	polymorphism	0,96	0,06	rs386420037	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7853	7853	G	A	MI.5758	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	268	90	V	I	Gtc/Atc	-0,17	0,28	0,11	benign	0	neutral	0,62	neutral	1,5	neutral	-0,38	neutral	0,52	neutral_impact	-0,22	neutral	0,85	neutral	0,99	neutral	-0,94	0,02	0,58	0,65	neutral	0,28	neutral	0,06	neutral	0,14	neutral	0,22	6	neutral	0,38	deleterious	0,81	neutral	-6	neutral	0,08	high_impact	2,08	medium_impact	0,32	low_impact	-1,31	0,64	0,8	25,11	28,78	N	0,42	N	0	polymorphism	1	0	rs386420037	.	.	.	.	.	COSM1155681	.	.	.	.	.	.	.	.
chrM	7854	7854	T	A	MI.5759	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	269	90	V	D	gTc/gAc	0,75	0,37	0	benign	0,4	neutral	0,69	neutral	1,19	deleterious	-4,84	deleterious	-5,83	medium_impact	2,88	damaging	0,57	neutral	0,43	deleterious	2,93	22	0,26	0,45	disease	0,69	disease	0,85	disease	0,6	disease	0,72	4	neutral	0,31	deleterious	0,65	neutral	-3	deleterious	0,55	medium_impact	-0,56	medium_impact	0,4	medium_impact	1,6	0,47	0,8	25,11	28,78	N	0,27	N	0,92	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8797	8797	T	C	MI.576	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	271	91	S	P	Tca/Cca	-1,72	0	0	probably_damaging	0,99	deleterious	0,03	neutral	4,19	deleterious	-3,36	deleterious	-3,42	medium_impact	2,44	neutral	0,65	damaging	0,08	deleterious	4	23,6	0,22	0,65	disease	0,77	disease	0,73	disease	0,54	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,85	low_impact	-2,65	medium_impact	-0,56	medium_impact	0,99	0,78	0,9	20,35	20,41	N	0,22	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7854	7854	T	G	MI.5760	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	269	90	V	G	gTc/gGc	0,75	0,37	0	benign	0,23	neutral	0,61	neutral	1,2	deleterious	-4,35	deleterious	-6,52	medium_impact	2,88	damaging	0,59	neutral	0,52	deleterious	2,21	17,57	0,26	0,45	disease	0,7	disease	0,75	disease	0,58	disease	0,67	3	neutral	0,28	deleterious	0,69	neutral	-3	deleterious	0,5	medium_impact	-0,23	medium_impact	0,31	medium_impact	1,6	0,56	0,8	25,11	28,78	N	0,28	N	0,92	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7854	7854	T	C	MI.5761	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	269	90	V	A	gTc/gCc	0,75	0,37	0	benign	0,04	neutral	0,87	neutral	1,28	neutral	-2,08	deleterious	-3,66	medium_impact	2,42	neutral	0,7	neutral	0,68	neutral	1,69	14,35	0,57	0,65	neutral	0,35	disease	0,5	disease	0,54	disease	0,59	2	neutral	0,06	deleterious	0,92	neutral	-3	neutral	0,2	medium_impact	0,57	medium_impact	0,66	medium_impact	1,16	0,3	0,8	25,11	28,78	N	0,29	N	0,7	polymorphism	0,96	0,07	.	.	.	.	.	.	COSM1132233	.	.	.	.	.	.	.	.
chrM	7856	7856	A	C	MI.5762	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	271	91	N	H	Aac/Cac	-9,16	0	0	probably_damaging	0,98	neutral	0,23	neutral	1,85	neutral	-1,99	deleterious	-3,79	medium_impact	2,1	damaging	0,55	neutral	0,31	deleterious	3,06	22,4	0,64	0,7	disease	0,61	disease	0,66	neutral	0,28	neutral	0,23	5	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,73	low_impact	-2,3	medium_impact	-0,09	medium_impact	0,86	0,34	0,8	67,4	16,13	N	0,35	N	0,64	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7856	7856	A	T	MI.5763	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	271	91	N	Y	Aac/Tac	-9,16	0	0	probably_damaging	0,99	neutral	0,28	neutral	1,85	deleterious	-3,04	deleterious	-5,95	low_impact	1,34	neutral	0,66	neutral	0,65	deleterious	2,65	20,5	0,46	0,55	disease	0,7	disease	0,76	neutral	0,27	neutral	0,26	5	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,77	low_impact	-2,58	medium_impact	-0,02	medium_impact	0,15	0,37	0,8	67,4	16,13	N	0,3	N	0,49	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7856	7856	A	G	MI.5764	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	271	91	N	D	Aac/Gac	-9,16	0	0	possibly_damaging	0,86	neutral	0,58	neutral	1,93	neutral	-0,7	deleterious	-3,53	low_impact	1,47	neutral	0,69	neutral	0,74	deleterious	2,64	20,4	0,72	0,75	neutral	0,22	disease	0,69	neutral	0,26	neutral	0,19	6	neutral	0,84	neutral	0,36	neutral	-3	deleterious	0,62	low_impact	-1,46	medium_impact	0,28	medium_impact	0,27	0,55	0,8	67,4	16,13	N	0,31	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7857	7857	A	T	MI.5765	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	272	91	N	I	aAc/aTc	2,14	0,73	0	probably_damaging	0,99	neutral	0,24	neutral	1,85	neutral	-1,64	deleterious	-6,94	low_impact	1,06	damaging	0,54	neutral	0,52	deleterious	2,89	21,8	0,42	0,55	disease	0,51	disease	0,8	neutral	0,24	neutral	0,2	6	deleterious	0,99	neutral	0,13	neutral	-2	deleterious	0,73	low_impact	-2,58	medium_impact	-0,07	medium_impact	-0,11	0,3	0,8	67,4	16,13	N	0,35	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7857	7857	A	G	MI.5766	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	272	91	N	S	aAc/aGc	2,14	0,73	0	possibly_damaging	0,69	neutral	0,76	neutral	1,92	neutral	0,21	deleterious	-3	neutral_impact	0,5	neutral	0,66	neutral	0,71	neutral	1,57	13,71	0,7	0,75	neutral	0,36	neutral	0,43	neutral	0,23	neutral	0,43	1	neutral	0,63	deleterious	0,54	neutral	-3	deleterious	0,61	low_impact	-1,04	medium_impact	0,48	medium_impact	-0,64	0,27	0,8	67,4	16,13	N	0,27	N	0,74	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7857	7857	A	C	MI.5767	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	272	91	N	T	aAc/aCc	2,14	0,73	0	probably_damaging	0,91	neutral	0,56	neutral	1,9	neutral	-0,49	deleterious	-4,17	low_impact	1,6	neutral	0,63	neutral	0,73	deleterious	3,31	22,9	0,6	0,65	neutral	0,44	disease	0,67	neutral	0,35	neutral	0,2	6	neutral	0,9	neutral	0,33	neutral	-2	deleterious	0,67	low_impact	-1,66	medium_impact	0,26	medium_impact	0,4	0,38	0,8	67,4	16,13	N	0,29	N	0,71	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7858	7858	C	A	MI.5768	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	273	91	N	K	aaC/aaA	3,98	0,77	0	probably_damaging	0,96	neutral	0,86	neutral	1,91	neutral	0,08	deleterious	-4,44	low_impact	0,99	damaging	0,46	neutral	0,32	deleterious	4,44	24,2	0,68	0,7	neutral	0,3	disease	0,77	neutral	0,41	neutral	0,38	2	neutral	0,96	neutral	0,45	neutral	-2	deleterious	0,72	low_impact	-2,01	medium_impact	0,64	medium_impact	-0,18	0,44	0,8	67,4	16,13	N	0,39	N	0,85	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7858	7858	C	G	MI.5769	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	273	91	N	K	aaC/aaG	3,98	0,77	0	probably_damaging	0,96	neutral	0,86	neutral	1,91	neutral	0,08	deleterious	-4,44	low_impact	0,99	damaging	0,46	neutral	0,32	deleterious	3,97	23,6	0,68	0,7	neutral	0,3	disease	0,77	neutral	0,41	neutral	0,38	2	neutral	0,96	neutral	0,45	neutral	-2	deleterious	0,72	low_impact	-2,01	medium_impact	0,64	medium_impact	-0,18	0,44	0,8	67,4	16,13	N	0,38	N	0,85	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8797	8797	T	A	MI.577	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	271	91	S	T	Tca/Aca	-1,72	0	0	probably_damaging	0,98	neutral	1	neutral	4,25	neutral	-1,4	neutral	0	neutral_impact	-0,88	neutral	0,87	neutral	0,92	neutral	1,16	11,55	0,37	0,65	disease	0,56	neutral	0,03	neutral	0,16	neutral	0,33	3	neutral	0,98	deleterious	0,51	neutral	-2	deleterious	0,66	low_impact	-2,36	high_impact	1,98	low_impact	-1,85	0,75	0,9	20,35	20,41	N	0,37	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7859	7859	G	A	MI.5770	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	274	92	D	N	Gat/Aat	-5,24	0	0,01	benign	0	neutral	0,4	neutral	2,01	neutral	0,05	neutral	0,64	neutral_impact	-0,33	neutral	0,9	neutral	0,99	neutral	-0,35	0,5	0,82	0,85	neutral	0,45	neutral	0,13	neutral	0,16	neutral	0,26	5	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,12	high_impact	2,08	medium_impact	0,11	low_impact	-1,42	0,61	0,8	29,52	32,33	P	0,63	P	0	polymorphism	1	0	rs373105186	.	.	.	.	.	.	.	.	G7859A	Progressive Encephalomyopathy	+	-	Reported	1
chrM	7859	7859	G	T	MI.5771	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	274	92	D	Y	Gat/Tat	-5,24	0	0,01	possibly_damaging	0,76	neutral	1	neutral	1,78	deleterious	-3,55	deleterious	-4,47	medium_impact	2,14	neutral	0,62	neutral	0,48	deleterious	3,6	23,2	0,36	0,5	disease	0,91	disease	0,72	disease	0,59	disease	0,68	4	neutral	0,76	deleterious	0,62	NA	0	deleterious	0,74	low_impact	-1,19	high_impact	1,86	medium_impact	0,9	0,29	0,8	29,52	32,33	N	0,19	N	0,9	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7859	7859	G	C	MI.5772	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	274	92	D	H	Gat/Cat	-5,24	0	0,01	possibly_damaging	0,61	neutral	0,54	neutral	1,8	neutral	-2,77	neutral	-2,38	medium_impact	2,09	neutral	0,64	neutral	0,45	deleterious	3,2	22,7	0,56	0,6	disease	0,84	disease	0,55	neutral	0,36	neutral	0,48	0	neutral	0,57	neutral	0,47	NA	0	deleterious	0,6	medium_impact	-0,9	medium_impact	0,24	medium_impact	0,85	0,61	0,8	29,52	32,33	N	0,21	N	0,39	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7860	7860	A	G	MI.5773	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	275	92	D	G	gAt/gGt	0,52	0,16	0	benign	0,12	neutral	0,35	neutral	1,86	neutral	-1,36	deleterious	-2,65	medium_impact	2,14	damaging	0,56	neutral	0,51	deleterious	2,24	17,75	0,54	0,6	disease	0,79	disease	0,65	disease	0,57	disease	0,67	3	neutral	0,6	deleterious	0,62	neutral	-3	neutral	0,31	medium_impact	0,09	medium_impact	0,06	medium_impact	0,9	0,32	0,8	29,52	32,33	N	0,28	N	0,41	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7860	7860	A	C	MI.5774	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	275	92	D	A	gAt/gCt	0,52	0,16	0	benign	0,17	neutral	0,53	neutral	1,84	neutral	-1,7	deleterious	-3,4	medium_impact	2,09	neutral	0,64	neutral	0,67	neutral	1,79	14,94	0,5	0,6	disease	0,69	disease	0,55	disease	0,56	disease	0,65	3	neutral	0,37	deleterious	0,68	neutral	-3	neutral	0,4	medium_impact	-0,08	medium_impact	0,23	medium_impact	0,85	0,5	0,8	29,52	32,33	N	0,28	N	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7860	7860	A	T	MI.5775	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	275	92	D	V	gAt/gTt	0,52	0,16	0	possibly_damaging	0,53	neutral	0,53	neutral	1,78	deleterious	-3,5	deleterious	-4,74	medium_impact	2,35	damaging	0,6	neutral	0,51	deleterious	2,33	18,33	0,4	0,5	disease	0,86	disease	0,72	disease	0,55	disease	0,65	3	neutral	0,5	deleterious	0,5	NA	0	deleterious	0,64	medium_impact	-0,77	medium_impact	0,23	medium_impact	1,1	0,32	0,8	29,52	32,33	N	0,26	N	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7861	7861	T	A	MI.5776	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	276	92	D	E	gaT/gaA	3,75	0,94	0,01	benign	0,12	neutral	0,33	neutral	1,93	neutral	-0,51	neutral	-1,43	neutral_impact	0,44	neutral	0,72	neutral	0,79	deleterious	0,75	9,17	0,65	0,7	neutral	0,27	neutral	0,4	neutral	0,22	neutral	0,45	1	neutral	0,62	deleterious	0,61	neutral	-6	neutral	0,23	medium_impact	0,09	medium_impact	0,04	medium_impact	-0,69	0,59	0,8	29,52	32,33	N	0,49	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7861	7861	T	G	MI.5777	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	276	92	D	E	gaT/gaG	3,75	0,94	0,01	benign	0,12	neutral	0,33	neutral	1,93	neutral	-0,51	neutral	-1,43	neutral_impact	0,44	neutral	0,72	neutral	0,79	deleterious	0,62	8,29	0,65	0,7	neutral	0,27	neutral	0,4	neutral	0,22	neutral	0,45	1	neutral	0,62	deleterious	0,61	neutral	-6	neutral	0,23	medium_impact	0,09	medium_impact	0,04	medium_impact	-0,69	0,59	0,8	29,52	32,33	N	0,49	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7862	7862	C	A	MI.5778	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	277	93	P	T	Ccc/Acc	0,29	0,94	0	probably_damaging	1	neutral	0,43	neutral	1,71	neutral	-2,68	deleterious	-7,65	medium_impact	3,25	damaging	0,13	damaging	0,02	deleterious	3,85	23,4	0,52	0,6	disease	0,61	disease	0,84	disease	0,53	disease	0,68	4	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,79	low_impact	-3,52	medium_impact	0,14	medium_impact	1,94	0,74	0,85	68,28	19,42	P	0,74	P	0,96	polymorphism	0,67	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7862	7862	C	T	MI.5779	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	277	93	P	S	Ccc/Tcc	0,29	0,94	0	probably_damaging	1	neutral	0,49	neutral	1,75	neutral	-1,87	deleterious	-7,61	medium_impact	2,81	damaging	0,11	damaging	0,03	deleterious	3,87	23,5	0,67	0,7	disease	0,51	disease	0,82	neutral	0,36	neutral	0,18	7	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,78	low_impact	-3,52	medium_impact	0,2	medium_impact	1,53	0,2	0,8	68,28	19,42	P	0,65	P	0,91	polymorphism	0,66	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8797	8797	T	G	MI.578	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	271	91	S	A	Tca/Gca	-1,72	0	0	probably_damaging	0,97	neutral	0,19	neutral	4,29	neutral	-0,93	neutral	-1,8	low_impact	1,05	neutral	0,83	neutral	0,41	deleterious	3,57	23,2	0,41	0,65	disease	0,59	neutral	0,18	neutral	0,3	neutral	0,4	2	neutral	0,98	neutral	0,11	neutral	-2	deleterious	0,71	low_impact	-2,19	medium_impact	-0,06	medium_impact	-0,2	0,76	0,9	20,35	20,41	N	0,39	N	0,44	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7862	7862	C	G	MI.5780	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	277	93	P	A	Ccc/Gcc	0,29	0,94	0	probably_damaging	0,98	neutral	0,54	neutral	1,76	neutral	-1,73	deleterious	-7,51	medium_impact	2,29	damaging	0,2	damaging	0,16	deleterious	3,07	22,4	0,47	0,55	neutral	0,38	disease	0,68	disease	0,55	neutral	0,49	0	neutral	0,98	neutral	0,28	deleterious	1	deleterious	0,72	low_impact	-2,3	medium_impact	0,24	medium_impact	1,04	0,78	0,85	68,28	19,42	P	0,83	P	0,9	polymorphism	0,76	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7863	7863	C	T	MI.5781	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	278	93	P	L	cCc/cTc	3,52	1	0	probably_damaging	1	neutral	0,42	neutral	1,67	deleterious	-3,81	deleterious	-9,61	high_impact	4,01	damaging	0,1	damaging	0,02	deleterious	4,44	24,2	0,45	0,55	disease	0,72	disease	0,87	disease	0,62	disease	0,68	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-3,52	medium_impact	0,13	high_impact	2,65	0,85	0,9	68,28	19,42	P	0,77	P	0,89	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7863	7863	C	G	MI.5782	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	278	93	P	R	cCc/cGc	3,52	1	0	probably_damaging	1	neutral	0,24	neutral	1,71	neutral	-2,65	deleterious	-8,65	high_impact	4,01	damaging	0,11	damaging	0,02	deleterious	3,65	23,2	0,47	0,55	disease	0,61	disease	0,89	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,81	low_impact	-3,52	medium_impact	-0,07	high_impact	2,65	0,61	0,8	68,28	19,42	P	0,83	P	0,82	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7863	7863	C	A	MI.5783	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	278	93	P	H	cCc/cAc	3,52	1	0	probably_damaging	1	neutral	0,07	neutral	1,68	deleterious	-3,5	deleterious	-8,68	high_impact	4,22	damaging	0,11	damaging	0,02	deleterious	4,06	23,7	0,55	0,6	disease	0,75	disease	0,86	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	-0,42	high_impact	2,85	0,62	0,8	68,28	19,42	P	0,84	P	0,79	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7865	7865	T	G	MI.5784	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	280	94	S	A	Tcc/Gcc	-16,08	0	0	possibly_damaging	0,9	neutral	0,53	neutral	2,05	neutral	0,85	neutral	-1,09	neutral_impact	0,76	neutral	0,73	neutral	0,86	deleterious	0,58	8,03	0,62	0,65	neutral	0,31	neutral	0,16	neutral	0,32	neutral	0,26	5	neutral	0,89	neutral	0,32	neutral	-3	deleterious	0,53	low_impact	-1,61	medium_impact	0,23	medium_impact	-0,39	0,71	0,85	24,67	37,99	N	0,35	N	0,19	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7865	7865	T	C	MI.5785	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	280	94	S	P	Tcc/Ccc	-16,08	0	0	probably_damaging	0,98	neutral	0,22	neutral	2,01	neutral	-0,98	neutral	-1,6	medium_impact	2,77	damaging	0,59	neutral	0,39	deleterious	3,55	23,1	0,45	0,55	disease	0,54	disease	0,72	neutral	0,3	neutral	0,4	2	deleterious	0,98	neutral	0,12	deleterious	1	deleterious	0,76	low_impact	-2,3	medium_impact	-0,1	medium_impact	1,49	0,59	0,8	24,67	37,99	N	0,37	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7865	7865	T	A	MI.5786	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	280	94	S	T	Tcc/Acc	-16,08	0	0	possibly_damaging	0,84	neutral	0,4	neutral	1,99	neutral	-0,35	neutral	-1,08	low_impact	1,44	neutral	0,76	neutral	0,97	deleterious	0,66	8,54	0,6	0,65	neutral	0,45	neutral	0,23	neutral	0,33	neutral	0,42	2	neutral	0,84	neutral	0,28	neutral	-3	deleterious	0,59	low_impact	-1,39	medium_impact	0,11	medium_impact	0,25	0,87	0,9	24,67	37,99	N	0,42	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7866	7866	C	G	MI.5787	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	281	94	S	C	tCc/tGc	-0,4	0	0	probably_damaging	0,99	neutral	0,18	neutral	1,92	deleterious	-4,56	neutral	-2,09	medium_impact	2,35	damaging	0,58	neutral	0,79	deleterious	2,23	17,71	0,45	0,55	disease	0,93	disease	0,53	neutral	0,23	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,76	low_impact	-2,58	medium_impact	-0,16	medium_impact	1,1	0,61	0,8	24,67	37,99	N	0,38	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7866	7866	C	A	MI.5788	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	281	94	S	Y	tCc/tAc	-0,4	0	0	probably_damaging	1	neutral	1	neutral	1,96	neutral	-2,74	neutral	1,46	low_impact	1,13	neutral	0,73	neutral	0,83	deleterious	0,74	9,07	0,44	0,55	disease	0,86	disease	0,52	neutral	0,22	neutral	0,5	0	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,78	low_impact	-3,52	high_impact	1,86	medium_impact	-0,05	0,71	0,85	24,67	37,99	N	0,24	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7866	7866	C	T	MI.5789	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	281	94	S	F	tCc/tTc	-0,4	0	0	probably_damaging	1	neutral	0,7	neutral	1,96	deleterious	-3,3	neutral	-0,62	low_impact	1,64	neutral	0,64	neutral	0,62	neutral	1,04	10,9	0,41	0,5	disease	0,89	disease	0,55	neutral	0,25	disease	0,54	1	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,78	low_impact	-3,52	medium_impact	0,41	medium_impact	0,43	0,52	0,8	24,67	37,99	N	0,28	N	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8798	8798	C	G	MI.579	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	272	91	S	W	tCa/tGa	2,67	0,96	0	probably_damaging	1	deleterious	0,02	neutral	4,18	deleterious	-3,54	deleterious	-4,88	medium_impact	2,98	neutral	0,77	damaging	0,11	deleterious	4,32	24	0,17	0,65	disease	0,96	disease	0,65	disease	0,63	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,84	low_impact	-3,6	medium_impact	-0,66	medium_impact	1,46	0,49	0,9	20,35	20,41	N	0,34	N	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7868	7868	C	A	MI.5790	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	283	95	L	I	Ctt/Att	-10,08	0	0	benign	0,14	neutral	0,41	neutral	1,93	neutral	-0,33	neutral	-1,55	low_impact	1,27	neutral	0,76	neutral	0,94	neutral	1,09	11,14	0,44	0,55	neutral	0,36	neutral	0,11	neutral	0,25	neutral	0,29	4	neutral	0,52	deleterious	0,64	neutral	-6	neutral	0,18	medium_impact	0,01	medium_impact	0,12	medium_impact	0,09	0,76	0,85	28,19	65,66	N	0,5	N	0,32	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7868	7868	C	G	MI.5791	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	283	95	L	V	Ctt/Gtt	-10,08	0	0	benign	0,06	neutral	0,25	neutral	2,03	neutral	0,12	neutral	-2,4	medium_impact	1,94	neutral	0,77	neutral	0,93	deleterious	0,47	7,17	0,42	0,55	disease	0,59	neutral	0,37	neutral	0,3	disease	0,61	2	neutral	0,73	deleterious	0,6	neutral	-3	neutral	0,21	medium_impact	0,39	medium_impact	-0,06	medium_impact	0,71	0,52	0,8	28,19	65,66	N	0,39	N	0,35	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7868	7868	C	T	MI.5792	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	283	95	L	F	Ctt/Ttt	-10,08	0	0	benign	0	neutral	0,36	neutral	1,7	neutral	-2,52	deleterious	-3,52	medium_impact	2,49	neutral	0,68	neutral	0,84	deleterious	2,01	16,26	0,44	0,55	disease	0,77	disease	0,57	neutral	0,48	neutral	0,42	2	neutral	0,64	deleterious	0,68	neutral	-3	neutral	0,26	high_impact	2,08	medium_impact	0,07	medium_impact	1,23	0,67	0,85	28,19	65,66	N	0,36	N	0	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	C7868T	LHON	+	-	Possibly synergistic	1
chrM	7869	7869	T	C	MI.5793	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	284	95	L	P	cTt/cCt	-4,32	0	0	probably_damaging	0,99	neutral	0,27	neutral	1,64	deleterious	-5,12	deleterious	-6,49	medium_impact	3,4	damaging	0,33	neutral	0,33	deleterious	3,88	23,5	0,12	0,4	disease	0,83	disease	0,84	disease	0,58	disease	0,67	3	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,87	low_impact	-2,58	medium_impact	-0,03	high_impact	2,08	0,43	0,8	28,19	65,66	P	0,52	P	0,97	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7869	7869	T	G	MI.5794	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	284	95	L	R	cTt/cGt	-4,32	0	0	probably_damaging	0,94	neutral	0,08	neutral	1,65	deleterious	-4,64	deleterious	-5,63	high_impact	4,09	damaging	0,36	neutral	0,31	deleterious	4,16	23,8	0,14	0,4	disease	0,7	disease	0,84	disease	0,7	disease	0,71	4	deleterious	0,98	neutral	0,07	deleterious	2	deleterious	0,73	low_impact	-1,83	medium_impact	-0,38	high_impact	2,73	0,61	0,8	28,19	65,66	P	0,54	P	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7869	7869	T	A	MI.5795	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	284	95	L	H	cTt/cAt	-4,32	0	0	probably_damaging	0,97	neutral	0,12	neutral	1,64	deleterious	-5,31	deleterious	-6,48	high_impact	4,09	damaging	0,46	neutral	0,4	deleterious	4,08	23,7	0,17	0,45	disease	0,81	disease	0,73	disease	0,67	disease	0,69	4	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,74	low_impact	-2,13	medium_impact	-0,27	high_impact	2,73	0,55	0,8	28,19	65,66	N	0,37	N	0,82	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7871	7871	A	G	MI.5796	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	286	96	T	A	Acc/Gcc	-9,39	0	0	probably_damaging	0,98	neutral	0,22	neutral	1,76	neutral	-2,18	deleterious	-4,89	high_impact	3,63	damaging	0,22	damaging	0,13	deleterious	3,53	23,1	0,47	0,55	disease	0,57	disease	0,58	disease	0,64	disease	0,63	3	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,74	low_impact	-2,3	medium_impact	-0,1	high_impact	2,3	0,39	0,8	68,72	19,4	P	0,75	P	0,65	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7871	7871	A	T	MI.5797	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	286	96	T	S	Acc/Tcc	-9,39	0	0	probably_damaging	0,98	neutral	0,78	neutral	1,77	neutral	-2,04	deleterious	-3,86	low_impact	1,75	damaging	0,18	damaging	0,06	deleterious	3,31	22,9	0,42	0,55	disease	0,57	neutral	0,49	neutral	0,42	neutral	0,24	5	deleterious	0,98	neutral	0,4	neutral	-2	deleterious	0,76	low_impact	-2,3	medium_impact	0,51	medium_impact	0,54	0,57	0,8	68,72	19,4	P	0,67	P	0,8	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7871	7871	A	C	MI.5798	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	286	96	T	P	Acc/Ccc	-9,39	0	0	probably_damaging	1	neutral	0,05	neutral	1,72	deleterious	-3,61	deleterious	-5,9	medium_impact	3,29	damaging	0,17	damaging	0,06	deleterious	3,5	23,1	0,15	0,4	neutral	0,35	disease	0,76	disease	0,66	disease	0,65	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,77	low_impact	-3,52	medium_impact	-0,5	medium_impact	1,98	0,51	0,8	68,72	19,4	P	0,67	P	0,9	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7872	7872	C	A	MI.5799	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	287	96	T	N	aCc/aAc	6,98	1	0	probably_damaging	1	neutral	0,17	neutral	1,74	neutral	-2,37	deleterious	-4,88	medium_impact	2,17	damaging	0,14	damaging	0,04	deleterious	3,64	23,2	0,44	0,55	disease	0,7	disease	0,78	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	-0,18	medium_impact	0,93	0,68	0,85	68,72	19,4	P	0,88	P	0,87	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8552	8552	T	G	MI.58	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	26	9	F	C	tTc/tGc	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	3,82	deleterious	-4,53	deleterious	-7,02	medium_impact	3,24	damaging	0,58	neutral	0,54	deleterious	3,85	23,4	0,26	0,65	disease	0,75	disease	0,83	disease	0,85	disease	0,85	7	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,82	low_impact	-2,65	low_impact	-1,4	medium_impact	1,68	0,21	0,9	49,56	8,77	P	0,58	P	1	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8798	8798	C	T	MI.580	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	272	91	S	L	tCa/tTa	2,67	0,96	0	probably_damaging	0,99	neutral	0,09	neutral	4,22	neutral	-2,06	deleterious	-3,89	low_impact	1,83	neutral	0,81	damaging	0,1	deleterious	4,64	24,5	0,34	0,65	disease	0,76	neutral	0,47	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,78	low_impact	-2,65	medium_impact	-0,28	medium_impact	0,47	0,84	0,9	20,35	20,41	N	0,38	N	0,93	polymorphism	0,94	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7872	7872	C	G	MI.5800	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	287	96	T	S	aCc/aGc	6,98	1	0	probably_damaging	0,98	neutral	0,78	neutral	1,77	neutral	-2,04	deleterious	-3,86	low_impact	1,75	damaging	0,18	damaging	0,06	deleterious	3,52	23,1	0,42	0,55	disease	0,57	neutral	0,49	neutral	0,42	neutral	0,24	5	deleterious	0,98	neutral	0,4	neutral	-2	deleterious	0,76	low_impact	-2,3	medium_impact	0,51	medium_impact	0,54	0,57	0,8	68,72	19,4	P	0,82	P	0,8	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7872	7872	C	T	MI.5801	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	287	96	T	I	aCc/aTc	6,98	1	0	probably_damaging	1	neutral	0,28	neutral	1,76	deleterious	-3,39	deleterious	-5,92	high_impact	3,52	damaging	0,16	damaging	0,03	deleterious	3,99	23,6	0,33	0,5	disease	0,56	disease	0,78	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,78	low_impact	-3,52	medium_impact	-0,02	high_impact	2,2	0,63	0,8	68,72	19,4	P	0,85	P	0,77	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7874	7874	A	C	MI.5802	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	289	97	I	L	Atc/Ctc	-7,32	0	0	probably_damaging	0,97	neutral	1	neutral	1,67	neutral	-2,73	neutral	-1,4	low_impact	1,55	neutral	0,65	neutral	0,82	deleterious	2,25	17,85	0,24	0,45	disease	0,55	neutral	0,12	neutral	0,27	neutral	0,27	5	neutral	0,97	deleterious	0,52	neutral	-2	deleterious	0,66	low_impact	-2,13	high_impact	1,86	medium_impact	0,35	0,62	0,8	32,6	59,31	N	0,26	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7874	7874	A	T	MI.5803	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	289	97	I	F	Atc/Ttc	-7,32	0	0	probably_damaging	0,99	neutral	0,39	neutral	1,5	deleterious	-4,72	deleterious	-3,65	medium_impact	2,24	damaging	0,5	neutral	0,35	deleterious	3,96	23,6	0,15	0,4	neutral	0,49	disease	0,65	disease	0,55	disease	0,56	1	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,74	low_impact	-2,58	medium_impact	0,1	medium_impact	1	0,71	0,85	32,6	59,31	N	0,33	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7874	7874	A	G	MI.5804	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	289	97	I	V	Atc/Gtc	-7,32	0	0	probably_damaging	0,97	neutral	0,46	neutral	1,96	neutral	-0,03	neutral	-0,44	neutral_impact	0,3	neutral	0,86	neutral	1	neutral	1,28	12,15	0,34	0,5	neutral	0,25	neutral	0,16	neutral	0,32	neutral	0,28	4	neutral	0,96	neutral	0,25	neutral	-2	deleterious	0,6	low_impact	-2,13	medium_impact	0,17	medium_impact	-0,82	0,59	0,8	32,6	59,31	N	0,34	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7875	7875	T	C	MI.5805	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	290	97	I	T	aTc/aCc	-0,17	0	0	probably_damaging	0,99	neutral	0,29	neutral	1,51	deleterious	-4,66	deleterious	-4,11	high_impact	3,56	damaging	0,59	neutral	0,33	deleterious	3,46	23	0,16	0,45	disease	0,84	disease	0,57	disease	0,65	disease	0,58	2	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,8	low_impact	-2,58	medium_impact	-0,01	high_impact	2,23	0,43	0,8	32,6	59,31	N	0,31	N	0,77	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7875	7875	T	A	MI.5806	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	290	97	I	N	aTc/aAc	-0,17	0	0	probably_damaging	1	neutral	0,2	neutral	1,47	deleterious	-6,53	deleterious	-6,34	high_impact	3,9	damaging	0,5	neutral	0,31	deleterious	4,46	24,2	0,11	0,4	disease	0,96	disease	0,8	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,13	high_impact	2,55	0,31	0,8	32,6	59,31	N	0,34	N	0,98	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7875	7875	T	G	MI.5807	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	290	97	I	S	aTc/aGc	-0,17	0	0	probably_damaging	0,99	neutral	0,37	neutral	1,48	deleterious	-5,24	deleterious	-5,35	medium_impact	3,21	damaging	0,54	neutral	0,37	deleterious	4,33	24	0,11	0,4	disease	0,92	disease	0,74	disease	0,67	disease	0,69	4	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,85	low_impact	-2,58	medium_impact	0,08	medium_impact	1,9	0,37	0,8	32,6	59,31	N	0,27	N	0,88	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7876	7876	C	G	MI.5808	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	291	97	I	M	atC/atG	5,83	0,94	0	probably_damaging	1	neutral	0,14	neutral	1,5	deleterious	-4,42	neutral	-2,15	medium_impact	2,55	neutral	0,66	neutral	0,57	deleterious	3,28	22,8	0,2	0,45	disease	0,83	neutral	0,33	neutral	0,37	disease	0,64	3	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,76	low_impact	-3,52	medium_impact	-0,23	medium_impact	1,29	0,68	0,85	32,6	59,31	P	0,54	P	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7876	7876	C	A	MI.5809	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	291	97	I	M	atC/atA	5,83	0,94	0	probably_damaging	1	neutral	0,14	neutral	1,5	deleterious	-4,42	neutral	-2,15	medium_impact	2,55	neutral	0,66	neutral	0,57	deleterious	3,76	23,3	0,2	0,45	disease	0,83	neutral	0,33	neutral	0,37	disease	0,64	3	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,76	low_impact	-3,52	medium_impact	-0,23	medium_impact	1,29	0,68	0,85	32,6	59,31	P	0,54	P	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8800	8800	T	A	MI.581	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	274	92	F	I	Ttt/Att	-3,34	0	0	probably_damaging	0,99	deleterious	0	neutral	4,12	neutral	-1,61	deleterious	-5,51	high_impact	3,71	damaging	0,58	damaging	0,1	deleterious	4,36	24,1	0,31	0,65	disease	0,65	disease	0,72	disease	0,77	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,65	low_impact	-1,4	high_impact	2,08	0,61	0,9	50	8,7	N	0,34	N	0,94	disease_causing	0,95	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7877	7877	A	C	MI.5810	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	292	98	K	Q	Aaa/Caa	-5,24	0	0	probably_damaging	1	neutral	0,25	neutral	1,71	neutral	-1,87	deleterious	-3,98	medium_impact	2,94	damaging	0,12	damaging	0,08	deleterious	3,47	23	0,28	0,45	disease	0,59	disease	0,82	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	-0,06	medium_impact	1,65	0,69	0,85	68,72	19,61	P	0,83	P	0,9	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	A7877C	PEG glaucoma	+	-	Reported	1
chrM	7877	7877	A	G	MI.5811	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	292	98	K	E	Aaa/Gaa	-5,24	0	0	probably_damaging	1	neutral	0,45	neutral	1,81	neutral	-0,45	deleterious	-3,98	medium_impact	2,99	damaging	0,11	damaging	0,05	deleterious	4,07	23,7	0,24	0,45	neutral	0,41	disease	0,88	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,83	low_impact	-3,52	medium_impact	0,16	medium_impact	1,7	0,77	0,85	68,72	19,61	P	0,81	P	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7878	7878	A	T	MI.5812	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	293	98	K	M	aAa/aTa	6,98	1	0	probably_damaging	1	neutral	0,07	neutral	1,62	deleterious	-4,26	deleterious	-5,97	high_impact	3,75	damaging	0,13	damaging	0,04	deleterious	4	23,6	0,15	0,4	disease	0,84	disease	0,82	disease	0,73	disease	0,64	3	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	-0,42	high_impact	2,41	0,43	0,8	68,72	19,61	P	0,9	P	0,75	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7878	7878	A	C	MI.5813	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	293	98	K	T	aAa/aCa	6,98	1	0	probably_damaging	1	neutral	0,3	neutral	1,68	neutral	-2,32	deleterious	-5,97	medium_impact	3,06	damaging	0,12	damaging	0,04	deleterious	3,73	23,3	0,16	0,45	disease	0,63	disease	0,87	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,84	low_impact	-3,52	medium_impact	0	medium_impact	1,76	0,52	0,8	68,72	19,61	P	0,89	P	0,88	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7879	7879	A	T	MI.5814	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	294	98	K	N	aaA/aaT	8,59	1	0,01	probably_damaging	1	neutral	0,21	neutral	1,7	neutral	-2,21	deleterious	-4,98	high_impact	3,52	damaging	0,11	damaging	0,03	deleterious	3,95	23,6	0,33	0,5	neutral	0,44	disease	0,85	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,52	medium_impact	-0,11	high_impact	2,2	0,64	0,8	68,72	19,61	P	0,91	P	0,84	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7879	7879	A	C	MI.5815	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	294	98	K	N	aaA/aaC	8,59	1	0,01	probably_damaging	1	neutral	0,21	neutral	1,7	neutral	-2,21	deleterious	-4,98	high_impact	3,52	damaging	0,11	damaging	0,03	deleterious	3,85	23,4	0,33	0,5	neutral	0,44	disease	0,85	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,52	medium_impact	-0,11	high_impact	2,2	0,64	0,8	68,72	19,61	P	0,91	P	0,84	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7880	7880	T	C	MI.5816	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	295	99	S	P	Tca/Cca	1,68	1	0	possibly_damaging	0,46	neutral	0,23	neutral	1,96	neutral	-1,49	neutral	-2,04	medium_impact	2,38	damaging	0,49	neutral	0,39	deleterious	2,49	19,42	0,12	0,4	disease	0,68	disease	0,85	disease	0,58	disease	0,73	5	neutral	0,74	neutral	0,39	NA	0	deleterious	0,46	medium_impact	-0,66	medium_impact	-0,09	medium_impact	1,13	0,63	0,8	32,16	66,63	N	0,51	P	0,68	polymorphism	0,9	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7880	7880	T	A	MI.5817	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	295	99	S	T	Tca/Aca	1,68	1	0	benign	0,14	neutral	0,74	neutral	2,03	neutral	0,16	neutral	0,64	neutral_impact	-0,66	neutral	0,76	neutral	0,96	deleterious	0,42	6,81	0,25	0,45	neutral	0,32	neutral	0,08	neutral	0,19	neutral	0,24	5	neutral	0,14	deleterious	0,8	neutral	-6	neutral	0,16	medium_impact	0,01	medium_impact	0,46	low_impact	-1,72	0,77	0,85	32,16	66,63	N	0,44	N	0	polymorphism	0,98	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7880	7880	T	G	MI.5818	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	295	99	S	A	Tca/Gca	1,68	1	0	benign	0	neutral	0,68	neutral	2,17	neutral	2,05	neutral	1,41	neutral_impact	-1,09	neutral	0,81	neutral	0,86	neutral	-0,87	0,03	0,24	0,45	neutral	0,41	neutral	0,11	neutral	0,2	neutral	0,25	5	neutral	0,31	deleterious	0,84	neutral	-6	neutral	0,13	high_impact	2,08	medium_impact	0,39	low_impact	-2,13	0,72	0,85	32,16	66,63	N	0,4	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7881	7881	C	T	MI.5819	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	296	99	S	L	tCa/tTa	1,91	1	0	benign	0,2	neutral	0,81	neutral	2,05	neutral	1,09	neutral	-1,99	low_impact	1,57	damaging	0,59	neutral	0,54	deleterious	2,82	21,5	0,15	0,4	neutral	0,35	disease	0,69	disease	0,57	disease	0,69	4	neutral	0,11	deleterious	0,81	neutral	-6	neutral	0,25	medium_impact	-0,16	medium_impact	0,55	medium_impact	0,37	0,75	0,85	32,16	66,63	N	0,36	N	0,66	polymorphism	0,93	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8800	8800	T	C	MI.582	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	274	92	F	L	Ttt/Ctt	-3,34	0	0	probably_damaging	0,98	deleterious	0,02	neutral	4,19	neutral	-1,01	deleterious	-5,51	high_impact	3,54	damaging	0,56	damaging	0,06	deleterious	3,98	23,6	0,44	0,65	disease	0,68	disease	0,69	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,77	low_impact	-2,36	medium_impact	-0,66	medium_impact	1,94	0,64	0,9	50	8,7	N	0,29	N	0,89	disease_causing	0,96	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7881	7881	C	G	MI.5820	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	296	99	S	W	tCa/tGa	1,91	1	0	possibly_damaging	0,85	neutral	0,25	neutral	1,95	neutral	-2,73	deleterious	-3,68	medium_impact	2,38	damaging	0,58	neutral	0,45	deleterious	4,26	23,9	0,1	0,4	disease	0,82	disease	0,84	disease	0,67	disease	0,74	5	neutral	0,89	neutral	0,2	NA	0	deleterious	0,77	low_impact	-1,42	medium_impact	-0,06	medium_impact	1,13	0,46	0,8	32,16	66,63	N	0,39	N	0,78	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7883	7883	A	C	MI.5821	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	298	100	I	L	Att/Ctt	-12,85	0	0	benign	0,07	neutral	0,79	neutral	1,91	neutral	-0,72	neutral	-0,53	low_impact	0,86	neutral	0,78	neutral	0,91	deleterious	0,63	8,39	0,39	0,5	neutral	0,27	disease	0,56	neutral	0,4	neutral	0,18	6	neutral	0,11	deleterious	0,86	neutral	-6	neutral	0,17	medium_impact	0,33	medium_impact	0,52	medium_impact	-0,3	0,68	0,85	28,63	65,81	N	0,26	N	0,48	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7883	7883	A	T	MI.5822	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	298	100	I	F	Att/Ttt	-12,85	0	0	possibly_damaging	0,55	neutral	0,32	neutral	1,81	neutral	-2,29	deleterious	-2,73	medium_impact	2,33	damaging	0,58	neutral	0,45	deleterious	3,7	23,3	0,33	0,5	disease	0,66	disease	0,77	disease	0,6	disease	0,65	3	neutral	0,67	neutral	0,39	NA	0	deleterious	0,51	medium_impact	-0,8	medium_impact	0,02	medium_impact	1,08	0,63	0,8	28,63	65,81	N	0,31	N	0,54	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7883	7883	A	G	MI.5823	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	298	100	I	V	Att/Gtt	-12,85	0	0	benign	0,01	neutral	0,66	neutral	1,95	neutral	0,17	neutral	-0,39	neutral_impact	0,6	neutral	0,79	neutral	0,93	neutral	-0,53	0,19	0,61	0,65	neutral	0,4	neutral	0,16	neutral	0,39	neutral	0,27	5	neutral	0,32	deleterious	0,83	neutral	-6	neutral	0,12	medium_impact	1,14	medium_impact	0,36	medium_impact	-0,54	0,39	0,8	28,63	65,81	N	0,35	N	0,55	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7884	7884	T	C	MI.5824	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	299	100	I	T	aTt/aCt	0,75	0,2	0	benign	0,33	neutral	0,77	neutral	1,92	neutral	1	deleterious	-3,36	neutral_impact	-0,06	neutral	0,66	neutral	0,66	deleterious	0,65	8,48	0,39	0,5	neutral	0,36	disease	0,7	neutral	0,45	neutral	0,18	6	neutral	0,22	deleterious	0,72	neutral	-6	neutral	0,27	medium_impact	-0,43	medium_impact	0,5	low_impact	-1,16	0,43	0,8	28,63	65,81	N	0,23	N	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7884	7884	T	G	MI.5825	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	299	100	I	S	aTt/aGt	0,75	0,2	0	possibly_damaging	0,62	neutral	0,7	neutral	1,81	neutral	-2,08	deleterious	-4,2	low_impact	1,84	damaging	0,57	neutral	0,47	deleterious	3,96	23,6	0,27	0,45	neutral	0,34	disease	0,81	disease	0,69	disease	0,67	3	neutral	0,55	deleterious	0,54	neutral	-3	neutral	0,4	medium_impact	-0,92	medium_impact	0,41	medium_impact	0,62	0,41	0,8	28,63	65,81	N	0,28	N	0,56	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7884	7884	T	A	MI.5826	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	299	100	I	N	aTt/aAt	0,75	0,2	0	possibly_damaging	0,88	neutral	0,34	neutral	1,79	neutral	-2,87	deleterious	-5,19	medium_impact	3,08	damaging	0,6	neutral	0,42	deleterious	4,43	24,2	0,25	0,45	disease	0,58	disease	0,86	disease	0,69	disease	0,7	4	neutral	0,89	neutral	0,23	NA	0	deleterious	0,71	low_impact	-1,53	medium_impact	0,05	medium_impact	1,78	0,39	0,8	28,63	65,81	N	0,3	N	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7885	7885	T	G	MI.5827	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	300	100	I	M	atT/atG	5,83	0,91	0	possibly_damaging	0,79	neutral	0,46	neutral	1,81	neutral	-1,6	neutral	-0,18	neutral_impact	0,8	neutral	0,79	neutral	0,98	neutral	1,41	12,82	0,4	0,5	neutral	0,44	neutral	0,34	neutral	0,37	neutral	0,44	1	neutral	0,78	neutral	0,34	neutral	-3	deleterious	0,45	low_impact	-1,26	medium_impact	0,17	medium_impact	-0,36	0,7	0,85	28,63	65,81	P	0,5	N	0,06	polymorphism	1	0,01	rs386829019	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7885	7885	T	A	MI.5828	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	300	100	I	M	atT/atA	5,83	0,91	0	possibly_damaging	0,79	neutral	0,46	neutral	1,81	neutral	-1,6	neutral	-0,18	neutral_impact	0,8	neutral	0,79	neutral	0,98	neutral	1,66	14,21	0,4	0,5	neutral	0,44	neutral	0,34	neutral	0,37	neutral	0,44	1	neutral	0,78	neutral	0,34	neutral	-3	deleterious	0,45	low_impact	-1,26	medium_impact	0,17	medium_impact	-0,36	0,7	0,85	28,63	65,81	P	0,5	N	0,06	polymorphism	1	0,01	rs386829019	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7886	7886	G	T	MI.5829	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	301	101	G	C	Ggc/Tgc	-3,17	0	0	probably_damaging	1	neutral	0,16	neutral	0,9	deleterious	-7,58	deleterious	-8,95	high_impact	4,65	damaging	0,27	damaging	0,12	deleterious	4,14	23,8	0,1	0,4	disease	0,95	disease	0,86	disease	0,74	disease	0,62	2	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	-0,19	high_impact	3,25	0,44	0,8	68,28	19,55	P	0,7	P	0,99	polymorphism	0,96	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8800	8800	T	G	MI.583	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	274	92	F	V	Ttt/Gtt	-3,34	0	0	probably_damaging	0,99	deleterious	0	neutral	4,1	neutral	-1,75	deleterious	-6,43	high_impact	4,17	damaging	0,55	damaging	0,09	deleterious	4,02	23,6	0,35	0,65	disease	0,57	disease	0,75	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-2,65	low_impact	-1,4	high_impact	2,48	0,51	0,9	50	8,7	N	0,37	N	0,99	disease_causing	0,98	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7886	7886	G	A	MI.5830	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	301	101	G	S	Ggc/Agc	-3,17	0	0	probably_damaging	1	neutral	0,4	neutral	1	deleterious	-4,08	deleterious	-5,96	medium_impact	3,21	damaging	0,28	damaging	0,15	deleterious	4,2	23,9	0,13	0,4	neutral	0,49	disease	0,78	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,83	low_impact	-3,52	medium_impact	0,11	medium_impact	1,9	0,54	0,8	68,28	19,55	P	0,72	P	0,98	polymorphism	0,99	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7886	7886	G	C	MI.5831	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	301	101	G	R	Ggc/Cgc	-3,17	0	0	probably_damaging	1	neutral	0,33	neutral	0,89	deleterious	-7,62	deleterious	-7,96	high_impact	4,3	damaging	0,28	damaging	0,1	deleterious	3,92	23,5	0,09	0,35	disease	0,96	disease	0,84	disease	0,83	disease	0,67	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	0,04	high_impact	2,93	0,51	0,8	68,28	19,55	P	0,7	P	1	polymorphism	0,98	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7887	7887	G	C	MI.5832	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	302	101	G	A	gGc/gCc	7,21	1	0	probably_damaging	1	neutral	0,5	neutral	1,26	neutral	-2,1	deleterious	-5,96	medium_impact	2,73	damaging	0,35	damaging	0,28	deleterious	3,09	22,5	0,15	0,45	neutral	0,32	disease	0,67	disease	0,65	disease	0,54	1	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,76	low_impact	-3,52	medium_impact	0,21	medium_impact	1,45	0,59	0,8	68,28	19,55	P	0,7	P	0,85	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7887	7887	G	T	MI.5833	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	302	101	G	V	gGc/gTc	7,21	1	0	probably_damaging	1	neutral	0,62	neutral	0,91	deleterious	-6,64	deleterious	-8,95	high_impact	4,3	damaging	0,28	damaging	0,13	deleterious	3,83	23,4	0,1	0,4	disease	0,92	disease	0,85	disease	0,73	disease	0,61	2	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,32	high_impact	2,93	0,36	0,8	68,28	19,55	P	0,76	P	1	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7887	7887	G	A	MI.5834	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	302	101	G	D	gGc/gAc	7,21	1	0	probably_damaging	1	neutral	0,22	neutral	0,9	deleterious	-6,82	deleterious	-6,96	high_impact	4,65	damaging	0,3	damaging	0,11	deleterious	3,88	23,5	0,1	0,4	disease	0,96	disease	0,85	disease	0,82	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	-0,1	high_impact	3,25	0,37	0,8	68,28	19,55	P	0,77	P	0,99	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7889	7889	C	G	MI.5835	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	304	102	H	D	Cac/Gac	-20	0	0	probably_damaging	1	neutral	0,62	neutral	1,84	neutral	-1,79	deleterious	-8,96	high_impact	4,4	damaging	0,21	damaging	0,02	deleterious	3,87	23,5	0,2	0,45	disease	0,63	disease	0,81	disease	0,77	disease	0,7	4	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	0,32	high_impact	3,02	0,44	0,8	68,28	19,75	P	0,5	N	0,97	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7889	7889	C	T	MI.5836	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	304	102	H	Y	Cac/Tac	-20	0	0	probably_damaging	1	neutral	0,4	neutral	1,81	neutral	-0,54	deleterious	-5,97	low_impact	1,8	damaging	0,19	damaging	0,01	deleterious	3,8	23,4	0,43	0,55	disease	0,62	disease	0,84	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,84	low_impact	-3,52	medium_impact	0,11	medium_impact	0,58	0,52	0,8	68,28	19,75	P	0,61	P	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7889	7889	C	A	MI.5837	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	304	102	H	N	Cac/Aac	-20	0	0	probably_damaging	1	neutral	0,54	neutral	1,84	neutral	-1,18	deleterious	-6,97	medium_impact	2,27	damaging	0,17	damaging	0,01	deleterious	3,92	23,5	0,38	0,5	neutral	0,31	disease	0,82	disease	0,69	disease	0,54	1	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,77	low_impact	-3,52	medium_impact	0,24	medium_impact	1,02	0,49	0,8	68,28	19,75	P	0,55	P	0,96	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7890	7890	A	C	MI.5838	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	305	102	H	P	cAc/cCc	7,21	1	0	probably_damaging	1	neutral	0,33	neutral	1,84	deleterious	-3,12	deleterious	-9,96	high_impact	4,4	damaging	0,17	damaging	0,02	deleterious	3,73	23,3	0,2	0,45	disease	0,74	disease	0,85	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,04	high_impact	3,02	0,38	0,8	68,28	19,75	P	0,78	P	0,98	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7890	7890	A	T	MI.5839	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	305	102	H	L	cAc/cTc	7,21	1	0	probably_damaging	1	neutral	0,56	neutral	1,86	neutral	-1,8	deleterious	-10,95	medium_impact	3,5	damaging	0,15	damaging	0,02	deleterious	4,37	24,1	0,24	0,45	neutral	0,32	disease	0,89	disease	0,74	disease	0,68	4	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,79	low_impact	-3,52	medium_impact	0,26	high_impact	2,18	0,46	0,8	68,28	19,75	P	0,75	P	0,91	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8801	8801	T	G	MI.584	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	275	92	F	C	tTt/tGt	5,68	1	0	probably_damaging	1	deleterious	0	neutral	4,02	deleterious	-3,07	deleterious	-7,37	high_impact	4,17	damaging	0,55	damaging	0,07	deleterious	4,04	23,7	0,33	0,65	disease	0,91	disease	0,8	disease	0,78	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,6	low_impact	-1,4	high_impact	2,48	0,26	0,9	50	8,7	P	0,54	P	1	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7890	7890	A	G	MI.5840	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	305	102	H	R	cAc/cGc	7,21	1	0	probably_damaging	1	neutral	0,63	neutral	1,88	neutral	-0,84	deleterious	-7,96	medium_impact	2,68	damaging	0,19	damaging	0,02	deleterious	3,52	23,1	0,44	0,55	neutral	0,36	disease	0,8	disease	0,67	disease	0,54	1	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	0,33	medium_impact	1,41	0,43	0,8	68,28	19,75	P	0,76	P	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7891	7891	C	A	MI.5841	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	306	102	H	Q	caC/caA	8,59	1	0	probably_damaging	1	neutral	0,68	neutral	1,86	neutral	-0,56	deleterious	-7,96	medium_impact	3,36	damaging	0,14	damaging	0,02	deleterious	3,94	23,5	0,47	0,55	disease	0,57	disease	0,76	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	0,39	high_impact	2,05	0,64	0,8	68,28	19,75	P	0,8	P	0,94	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7891	7891	C	G	MI.5842	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	306	102	H	Q	caC/caG	8,59	1	0	probably_damaging	1	neutral	0,68	neutral	1,86	neutral	-0,56	deleterious	-7,96	medium_impact	3,36	damaging	0,14	damaging	0,02	deleterious	3,6	23,2	0,47	0,55	disease	0,57	disease	0,76	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	0,39	high_impact	2,05	0,64	0,8	68,28	19,75	P	0,8	P	0,94	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7892	7892	C	G	MI.5843	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	307	103	Q	E	Caa/Gaa	-5,47	0	0	probably_damaging	0,94	neutral	0,32	neutral	1,6	deleterious	-3,23	deleterious	-2,99	high_impact	3,98	damaging	0,33	damaging	0,24	deleterious	3,05	22,4	0,29	0,45	disease	0,58	disease	0,73	disease	0,81	disease	0,67	3	neutral	0,95	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-1,83	medium_impact	0,02	high_impact	2,63	0,69	0,85	68,72	19,57	P	0,58	P	0,85	polymorphism	0,95	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7892	7892	C	A	MI.5844	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	307	103	Q	K	Caa/Aaa	-5,47	0	0	probably_damaging	0,98	neutral	0,24	neutral	1,6	neutral	-2,87	deleterious	-3,98	high_impact	4,33	damaging	0,32	damaging	0,23	deleterious	4,07	23,7	0,26	0,45	neutral	0,46	disease	0,75	disease	0,8	disease	0,67	3	deleterious	0,98	neutral	0,13	deleterious	2	deleterious	0,81	low_impact	-2,3	medium_impact	-0,07	high_impact	2,95	0,61	0,8	68,72	19,57	P	0,66	P	0,97	polymorphism	0,9	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7893	7893	A	G	MI.5845	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	308	103	Q	R	cAa/cGa	7,21	1	0	probably_damaging	0,98	neutral	0,28	neutral	1,55	deleterious	-3,7	deleterious	-3,98	high_impact	3,58	damaging	0,32	damaging	0,25	deleterious	3,5	23,1	0,26	0,45	disease	0,55	disease	0,81	disease	0,78	disease	0,69	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-2,3	medium_impact	-0,02	high_impact	2,25	0,58	0,8	68,72	19,57	P	0,79	P	0,95	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7893	7893	A	C	MI.5846	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	308	103	Q	P	cAa/cCa	7,21	1	0	probably_damaging	0,99	neutral	0,24	neutral	1,51	deleterious	-5,37	deleterious	-5,97	high_impact	4,12	damaging	0,33	damaging	0,22	deleterious	3,39	23	0,2	0,45	disease	0,69	disease	0,83	disease	0,74	disease	0,7	4	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,88	low_impact	-2,58	medium_impact	-0,07	high_impact	2,76	0,54	0,8	68,72	19,57	P	0,74	P	0,95	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7893	7893	A	T	MI.5847	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	308	103	Q	L	cAa/cTa	7,21	1	0	probably_damaging	0,98	neutral	0,56	neutral	1,51	deleterious	-3,88	deleterious	-6,97	high_impact	3,7	damaging	0,29	neutral	0,37	deleterious	3,82	23,4	0,17	0,45	neutral	0,5	disease	0,87	disease	0,73	disease	0,7	4	neutral	0,97	neutral	0,29	deleterious	2	deleterious	0,84	low_impact	-2,3	medium_impact	0,26	high_impact	2,36	0,39	0,8	68,72	19,57	P	0,89	P	0,97	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7894	7894	A	T	MI.5848	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	309	103	Q	H	caA/caT	5,6	1	0	probably_damaging	1	neutral	0,52	neutral	1,49	deleterious	-5,12	deleterious	-4,98	high_impact	4,33	damaging	0,3	damaging	0,22	deleterious	3,64	23,2	0,31	0,45	disease	0,81	disease	0,74	disease	0,81	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,22	high_impact	2,95	0,77	0,85	68,72	19,57	P	0,84	P	0,86	disease_causing	1	0,28	rs386829020	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7894	7894	A	C	MI.5849	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	309	103	Q	H	caA/caC	5,6	1	0	probably_damaging	1	neutral	0,52	neutral	1,49	deleterious	-5,12	deleterious	-4,98	high_impact	4,33	damaging	0,3	damaging	0,22	deleterious	3,59	23,2	0,31	0,45	disease	0,81	disease	0,74	disease	0,81	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,22	high_impact	2,95	0,77	0,85	68,72	19,57	P	0,83	P	0,86	disease_causing	1	0,28	rs386829020	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8801	8801	T	C	MI.585	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	275	92	F	S	tTt/tCt	5,68	1	0	probably_damaging	0,99	deleterious	0	neutral	4,01	deleterious	-3,36	deleterious	-7,31	medium_impact	3,42	damaging	0,55	damaging	0,11	deleterious	4,24	23,9	0,33	0,65	disease	0,74	disease	0,78	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,81	low_impact	-2,65	low_impact	-1,4	medium_impact	1,83	0,31	0,9	50	8,7	N	0,47	N	0,99	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7895	7895	T	G	MI.5850	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	310	104	W	G	Tgg/Ggg	-0,17	0,58	0	probably_damaging	1	neutral	0,28	neutral	1,02	deleterious	-7,74	deleterious	-12,94	high_impact	4,68	damaging	0,16	damaging	0,01	deleterious	3,93	23,5	0,15	0,4	disease	0,95	disease	0,8	disease	0,81	disease	0,7	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,02	high_impact	3,28	0,19	0,8	68,72	19,46	P	0,66	P	0,98	disease_causing	0,96	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7895	7895	T	C	MI.5851	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	310	104	W	R	Tgg/Cgg	-0,17	0,58	0	probably_damaging	1	neutral	0,15	neutral	1,03	deleterious	-7,42	deleterious	-13,94	high_impact	4,68	damaging	0,19	damaging	0,01	deleterious	3,65	23,2	0,18	0,45	disease	0,94	disease	0,86	disease	0,84	disease	0,64	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	-0,21	high_impact	3,28	0,19	0,8	68,72	19,46	P	0,64	P	0,96	disease_causing	0,9	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7896	7896	G	T	MI.5852	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	311	104	W	L	tGg/tTg	5,6	1	0	probably_damaging	1	neutral	0,39	neutral	1,15	deleterious	-5,63	deleterious	-12,94	high_impact	4,34	damaging	0,22	damaging	0,02	deleterious	4,28	24	0,12	0,4	disease	0,88	disease	0,84	disease	0,79	disease	0,63	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	0,1	high_impact	2,96	0,17	0,8	68,72	19,46	P	0,72	P	0,98	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7896	7896	G	C	MI.5853	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	311	104	W	S	tGg/tCg	5,6	1	0	probably_damaging	1	neutral	0,17	neutral	1,03	deleterious	-7,15	deleterious	-13,94	high_impact	4,34	damaging	0,15	damaging	0,01	deleterious	4,05	23,7	0,15	0,4	disease	0,63	disease	0,85	disease	0,79	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,18	high_impact	2,96	0,2	0,8	68,72	19,46	P	0,7	P	0,97	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7897	7897	G	C	MI.5854	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	312	104	W	C	tgG/tgC	7,44	1	0	probably_damaging	1	neutral	0,08	neutral	1,02	deleterious	-8,62	deleterious	-12,94	high_impact	4,68	damaging	0,16	damaging	0,01	deleterious	4,03	23,7	0,17	0,45	disease	0,98	disease	0,85	disease	0,83	disease	0,67	3	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,38	high_impact	3,28	0,26	0,8	68,72	19,46	P	0,7	P	0,94	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7897	7897	G	T	MI.5855	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	312	104	W	C	tgG/tgT	7,44	1	0	probably_damaging	1	neutral	0,08	neutral	1,02	deleterious	-8,62	deleterious	-12,94	high_impact	4,68	damaging	0,16	damaging	0,01	deleterious	4,19	23,8	0,17	0,45	disease	0,98	disease	0,85	disease	0,83	disease	0,67	3	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,38	high_impact	3,28	0,26	0,8	68,72	19,46	P	0,7	P	0,94	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7898	7898	T	C	MI.5856	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	313	105	Y	H	Tac/Cac	3,29	1	0	probably_damaging	1	neutral	0,25	neutral	1,78	neutral	-2,59	deleterious	-4,97	high_impact	4,32	damaging	0,12	damaging	0,03	deleterious	3,64	23,2	0,4	0,5	disease	0,7	disease	0,72	disease	0,78	disease	0,7	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	-0,06	high_impact	2,95	0,36	0,8	68,28	19,32	P	0,87	P	0,94	disease_causing	0,88	0,09	.	.	.	.	.	.	COSM488771	.	.	.	.	.	.	.	.
chrM	7898	7898	T	G	MI.5857	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	313	105	Y	D	Tac/Gac	3,29	1	0	probably_damaging	1	neutral	0,1	neutral	1,79	neutral	-1,63	deleterious	-9,95	high_impact	4,32	damaging	0,19	damaging	0,02	deleterious	4,01	23,6	0,22	0,45	disease	0,58	disease	0,83	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	-0,32	high_impact	2,95	0,28	0,8	68,28	19,32	P	0,79	P	0,99	disease_causing	0,98	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7898	7898	T	A	MI.5858	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	313	105	Y	N	Tac/Aac	3,29	1	0	probably_damaging	1	neutral	0,08	neutral	1,81	neutral	-0,92	deleterious	-8,95	medium_impact	3,22	damaging	0,16	damaging	0,02	deleterious	4,09	23,7	0,35	0,5	disease	0,57	disease	0,86	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,82	low_impact	-3,52	medium_impact	-0,38	medium_impact	1,91	0,23	0,8	68,28	19,32	P	0,83	P	0,99	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7899	7899	A	T	MI.5859	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	314	105	Y	F	tAc/tTc	7,44	1	0	probably_damaging	1	neutral	0,22	neutral	1,82	neutral	-2,55	deleterious	-3,97	low_impact	1,46	damaging	0,21	damaging	0,08	deleterious	3,46	23	0,39	0,5	disease	0,67	disease	0,75	disease	0,61	neutral	0,37	3	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,83	low_impact	-3,52	medium_impact	-0,1	medium_impact	0,26	0,5	0,8	68,28	19,32	P	0,88	P	0,87	disease_causing	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8801	8801	T	A	MI.586	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	275	92	F	Y	tTt/tAt	5,68	1	0	probably_damaging	0,98	neutral	0,15	neutral	4,02	deleterious	-3,03	deleterious	-2,73	medium_impact	2,24	neutral	0,62	damaging	0,13	deleterious	4,23	23,9	0,42	0,65	disease	0,78	disease	0,61	disease	0,57	neutral	0,37	3	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,79	low_impact	-2,36	medium_impact	-0,13	medium_impact	0,82	0,68	0,9	50	8,7	P	0,57	P	0,89	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7899	7899	A	G	MI.5860	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	314	105	Y	C	tAc/tGc	7,44	1	0	probably_damaging	1	neutral	0,05	neutral	1,77	deleterious	-4,54	deleterious	-8,94	high_impact	4,32	damaging	0,13	damaging	0,02	deleterious	3,56	23,1	0,36	0,5	disease	0,86	disease	0,84	disease	0,74	disease	0,64	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,5	high_impact	2,95	0,16	0,8	68,28	19,32	P	0,84	P	0,96	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7899	7899	A	C	MI.5861	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	314	105	Y	S	tAc/tCc	7,44	1	0	probably_damaging	1	neutral	0,1	neutral	1,83	neutral	-0,7	deleterious	-8,95	high_impact	3,77	damaging	0,13	damaging	0,03	deleterious	3,77	23,4	0,29	0,45	neutral	0,43	disease	0,8	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	-0,32	high_impact	2,43	0,24	0,8	68,28	19,32	P	0,85	P	0,99	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7901	7901	T	C	MI.5862	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	316	106	W	R	Tga/Cga	-1,32	0	0	probably_damaging	1	neutral	0,05	neutral	1,47	deleterious	-6,31	deleterious	-13,94	high_impact	4,12	damaging	0,19	damaging	0,01	deleterious	3,64	23,2	0,19	0,45	disease	0,85	disease	0,88	disease	0,84	disease	0,66	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	-0,5	high_impact	2,76	0,19	0,8	68,72	19,55	P	0,64	P	0,96	disease_causing	0,74	0,28	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	7901	7901	T	G	MI.5863	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	316	106	W	G	Tga/Gga	-1,32	0	0	probably_damaging	1	neutral	0,05	neutral	1,46	deleterious	-7,79	deleterious	-12,94	high_impact	4,33	damaging	0,15	damaging	0,01	deleterious	3,93	23,5	0,16	0,45	disease	0,9	disease	0,81	disease	0,8	disease	0,65	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	-0,5	high_impact	2,95	0,25	0,8	68,72	19,55	P	0,63	P	0,98	disease_causing	0,88	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7902	7902	G	T	MI.5864	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	317	106	W	L	tGa/tTa	5,83	1	0	probably_damaging	1	neutral	0,16	neutral	1,52	deleterious	-5,67	deleterious	-12,94	high_impact	4,33	damaging	0,2	damaging	0,02	deleterious	4,21	23,9	0,13	0,4	disease	0,89	disease	0,86	disease	0,79	disease	0,62	2	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,19	high_impact	2,95	0,2	0,8	68,72	19,55	P	0,74	P	0,98	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7902	7902	G	C	MI.5865	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	317	106	W	S	tGa/tCa	5,83	1	0	probably_damaging	1	neutral	0,23	neutral	1,48	deleterious	-6,83	deleterious	-13,94	high_impact	4,12	damaging	0,14	damaging	0,01	deleterious	4,03	23,6	0,16	0,45	disease	0,72	disease	0,88	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	-0,09	high_impact	2,76	0,21	0,8	68,72	19,55	P	0,71	P	0,97	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7903	7903	A	C	MI.5866	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	318	106	W	C	tgA/tgC	7,21	1	0	probably_damaging	1	deleterious	0,03	neutral	1,43	deleterious	-8,59	deleterious	-12,94	high_impact	4,67	damaging	0,16	damaging	0,01	deleterious	4,05	23,7	0,18	0,45	disease	0,96	disease	0,88	disease	0,81	disease	0,63	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,91	low_impact	-3,52	medium_impact	-0,63	high_impact	3,27	0,24	0,8	68,72	19,55	P	0,72	P	0,94	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7903	7903	A	T	MI.5867	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	318	106	W	C	tgA/tgT	7,21	1	0	probably_damaging	1	deleterious	0,03	neutral	1,43	deleterious	-8,59	deleterious	-12,94	high_impact	4,67	damaging	0,16	damaging	0,01	deleterious	4,17	23,8	0,18	0,45	disease	0,96	disease	0,88	disease	0,81	disease	0,63	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,91	low_impact	-3,52	medium_impact	-0,63	high_impact	3,27	0,24	0,8	68,72	19,55	P	0,73	P	0,94	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7904	7904	A	C	MI.5868	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	319	107	T	P	Acc/Ccc	5,83	1	0	possibly_damaging	0,46	neutral	0,2	neutral	1,9	neutral	-2,11	deleterious	-2,56	medium_impact	2,48	damaging	0,58	neutral	0,37	deleterious	3,29	22,8	0,11	0,4	disease	0,81	disease	0,8	disease	0,58	disease	0,72	4	neutral	0,77	neutral	0,37	NA	0	deleterious	0,7	medium_impact	-0,66	medium_impact	-0,13	medium_impact	1,22	0,63	0,8	28,19	64,45	P	0,53	P	0,61	disease_causing	0,97	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7904	7904	A	T	MI.5869	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	319	107	T	S	Acc/Tcc	5,83	1	0	benign	0,14	neutral	0,51	neutral	2,27	neutral	1,73	neutral	1,76	neutral_impact	-1,77	neutral	0,72	neutral	0,97	neutral	-1,11	0,01	0,27	0,45	neutral	0,37	neutral	0,02	neutral	0,16	neutral	0,22	6	neutral	0,4	deleterious	0,69	neutral	-6	neutral	0,22	medium_impact	0,01	medium_impact	0,21	low_impact	-2,77	0,68	0,85	28,19	64,45	P	0,62	P	0,01	disease_causing	0,66	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8802	8802	T	A	MI.587	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	276	92	F	L	ttT/ttA	4,52	1	0	probably_damaging	0,98	deleterious	0,02	neutral	4,19	neutral	-1,01	deleterious	-5,51	high_impact	3,54	damaging	0,56	damaging	0,06	deleterious	4,39	24,1	0,44	0,65	disease	0,68	disease	0,69	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,77	low_impact	-2,36	medium_impact	-0,66	medium_impact	1,94	0,64	0,9	50	8,7	P	0,54	P	0,89	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7904	7904	A	G	MI.5870	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	319	107	T	A	Acc/Gcc	5,83	1	0	benign	0,01	neutral	0,47	neutral	1,99	neutral	-0,13	neutral	-0,64	low_impact	1,45	neutral	0,83	neutral	0,76	neutral	1,63	14	0,28	0,45	disease	0,59	neutral	0,47	disease	0,59	disease	0,63	3	neutral	0,52	deleterious	0,73	neutral	-6	neutral	0,29	medium_impact	1,14	medium_impact	0,18	medium_impact	0,25	0,57	0,8	28,19	64,45	N	0,53	P	0,14	disease_causing	0,85	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7905	7905	C	T	MI.5871	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	320	107	T	I	aCc/aTc	3,06	1	0	benign	0,31	neutral	0,36	neutral	1,91	neutral	-1,77	deleterious	-3,38	low_impact	1,94	neutral	0,66	neutral	0,58	deleterious	2,25	17,86	0,33	0,5	disease	0,54	disease	0,6	disease	0,56	disease	0,68	4	neutral	0,57	deleterious	0,53	neutral	-6	deleterious	0,47	medium_impact	-0,4	medium_impact	0,07	medium_impact	0,71	0,75	0,85	28,19	64,45	N	0,45	N	0,78	polymorphism	0,77	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7905	7905	C	G	MI.5872	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	320	107	T	S	aCc/aGc	3,06	1	0	benign	0,14	neutral	0,51	neutral	2,27	neutral	1,73	neutral	1,76	neutral_impact	-1,77	neutral	0,72	neutral	0,97	neutral	-1,01	0,02	0,27	0,45	neutral	0,37	neutral	0,02	neutral	0,16	neutral	0,22	6	neutral	0,4	deleterious	0,69	neutral	-6	neutral	0,22	medium_impact	0,01	medium_impact	0,21	low_impact	-2,77	0,68	0,85	28,19	64,45	P	0,53	P	0,01	polymorphism	0,97	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7905	7905	C	A	MI.5873	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	320	107	T	N	aCc/aAc	3,06	1	0	possibly_damaging	0,46	neutral	0,28	neutral	1,93	neutral	-1,06	neutral	-0,8	neutral_impact	0,13	neutral	0,63	neutral	0,58	deleterious	2,24	17,75	0,36	0,5	disease	0,66	disease	0,76	neutral	0,42	neutral	0,28	4	neutral	0,69	neutral	0,41	neutral	-3	deleterious	0,56	medium_impact	-0,66	medium_impact	-0,02	medium_impact	-0,98	0,62	0,8	28,19	64,45	N	0,42	N	0,37	polymorphism	0,78	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7907	7907	T	C	MI.5874	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	322	108	Y	H	Tac/Cac	-2,01	0	0	probably_damaging	1	neutral	0,13	neutral	0,98	deleterious	-5,46	deleterious	-4,98	high_impact	3,92	damaging	0,11	damaging	0,02	deleterious	3,63	23,2	0,27	0,45	disease	0,86	disease	0,75	disease	0,76	disease	0,65	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,25	high_impact	2,57	0,37	0,8	67,84	19,73	P	0,81	P	0,94	disease_causing	0,57	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7907	7907	T	A	MI.5875	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	322	108	Y	N	Tac/Aac	-2,01	0	0	probably_damaging	1	neutral	0,13	neutral	0,98	deleterious	-5,84	deleterious	-8,96	high_impact	4,27	damaging	0,15	damaging	0,02	deleterious	4,11	23,8	0,27	0,45	disease	0,87	disease	0,86	disease	0,75	disease	0,62	2	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	-0,25	high_impact	2,9	0,21	0,8	67,84	19,73	P	0,71	P	0,99	disease_causing	0,94	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7907	7907	T	G	MI.5876	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	322	108	Y	D	Tac/Gac	-2,01	0	0	probably_damaging	1	neutral	0,1	neutral	0,97	deleterious	-6,09	deleterious	-9,96	high_impact	4,62	damaging	0,18	damaging	0,02	deleterious	4,05	23,7	0,18	0,45	disease	0,92	disease	0,84	disease	0,8	disease	0,67	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,32	high_impact	3,23	0,29	0,8	67,84	19,73	P	0,69	P	0,99	disease_causing	0,92	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7908	7908	A	G	MI.5877	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	323	108	Y	C	tAc/tGc	7,44	1	0	probably_damaging	1	deleterious	0,04	neutral	0,96	deleterious	-7,26	deleterious	-8,96	high_impact	4,27	damaging	0,13	damaging	0,03	deleterious	3,63	23,2	0,32	0,5	disease	0,89	disease	0,85	disease	0,76	disease	0,62	2	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,88	low_impact	-3,52	medium_impact	-0,56	high_impact	2,9	0,23	0,8	67,84	19,73	P	0,82	P	0,96	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7908	7908	A	C	MI.5878	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	323	108	Y	S	tAc/tCc	7,44	1	0	probably_damaging	1	neutral	0,16	neutral	0,99	deleterious	-5,38	deleterious	-8,96	high_impact	4,27	damaging	0,11	damaging	0,03	deleterious	3,81	23,4	0,23	0,45	disease	0,77	disease	0,8	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,19	high_impact	2,9	0,29	0,8	67,84	19,73	P	0,84	P	0,99	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7908	7908	A	T	MI.5879	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	323	108	Y	F	tAc/tTc	7,44	1	0	probably_damaging	0,99	neutral	0,17	neutral	1,1	deleterious	-3,31	deleterious	-3,98	medium_impact	2,8	damaging	0,14	damaging	0,02	deleterious	3,55	23,1	0,27	0,45	neutral	0,3	disease	0,8	disease	0,67	disease	0,65	3	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,78	low_impact	-2,58	medium_impact	-0,18	medium_impact	1,52	0,51	0,8	67,84	19,73	P	0,89	P	0,87	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8802	8802	T	G	MI.588	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	276	92	F	L	ttT/ttG	4,52	1	0	probably_damaging	0,98	deleterious	0,02	neutral	4,19	neutral	-1,01	deleterious	-5,51	high_impact	3,54	damaging	0,56	damaging	0,06	deleterious	4,28	24	0,44	0,65	disease	0,68	disease	0,69	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,77	low_impact	-2,36	medium_impact	-0,66	medium_impact	1,94	0,64	0,9	50	8,7	P	0,53	P	0,89	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7910	7910	G	C	MI.5880	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	325	109	E	Q	Gag/Cag	-2,71	0	0	probably_damaging	1	neutral	0,2	neutral	1,54	neutral	-2,62	deleterious	-2,98	medium_impact	2,9	damaging	0,16	damaging	0,06	deleterious	3,4	23	0,33	0,5	disease	0,52	disease	0,67	disease	0,66	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	-0,13	medium_impact	1,61	0,71	0,85	67,4	19,68	P	0,8	P	0,76	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7910	7910	G	A	MI.5881	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	325	109	E	K	Gag/Aag	-2,71	0	0	probably_damaging	1	neutral	0,24	neutral	1,54	neutral	-2,62	deleterious	-3,98	medium_impact	3,17	damaging	0,13	damaging	0,02	deleterious	4,55	24,4	0,29	0,45	neutral	0,37	disease	0,82	disease	0,78	disease	0,68	4	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,83	low_impact	-3,52	medium_impact	-0,07	medium_impact	1,87	0,77	0,85	67,4	19,68	P	0,8	P	0,99	polymorphism	0,98	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7911	7911	A	G	MI.5882	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	326	109	E	G	gAg/gGg	6,06	1	0	probably_damaging	1	neutral	0,22	neutral	1,48	deleterious	-3,74	deleterious	-6,97	high_impact	3,86	damaging	0,11	damaging	0,05	deleterious	4,41	24,1	0,29	0,45	disease	0,7	disease	0,73	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	-0,1	high_impact	2,51	0,35	0,8	67,4	19,68	P	0,89	P	0,64	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7911	7911	A	C	MI.5883	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	326	109	E	A	gAg/gCg	6,06	1	0	probably_damaging	1	neutral	0,34	neutral	1,51	deleterious	-3,15	deleterious	-5,97	medium_impact	3,4	damaging	0,2	damaging	0,1	deleterious	3,82	23,4	0,27	0,45	disease	0,54	disease	0,77	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,82	low_impact	-3,52	medium_impact	0,05	high_impact	2,08	0,48	0,8	67,4	19,68	P	0,9	P	0,66	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7911	7911	A	T	MI.5884	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	326	109	E	V	gAg/gTg	6,06	1	0	probably_damaging	1	neutral	0,38	neutral	1,46	deleterious	-4,34	deleterious	-6,97	medium_impact	3,46	damaging	0,13	damaging	0,03	deleterious	4,39	24,1	0,23	0,45	disease	0,72	disease	0,87	disease	0,78	disease	0,7	4	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,87	low_impact	-3,52	medium_impact	0,09	high_impact	2,14	0,55	0,8	67,4	19,68	P	0,88	P	0,82	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7912	7912	G	C	MI.5885	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	327	109	E	D	gaG/gaC	6,98	1	0,01	probably_damaging	0,99	neutral	0,14	neutral	1,56	neutral	-2,3	deleterious	-2,99	medium_impact	2,66	damaging	0,2	damaging	0,04	deleterious	3,75	23,3	0,29	0,45	neutral	0,42	disease	0,71	disease	0,73	disease	0,67	3	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,79	low_impact	-2,58	medium_impact	-0,23	medium_impact	1,39	0,75	0,85	67,4	19,68	P	0,89	P	0,81	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7912	7912	G	T	MI.5886	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	327	109	E	D	gaG/gaT	6,98	1	0,01	probably_damaging	0,99	neutral	0,14	neutral	1,56	neutral	-2,3	deleterious	-2,99	medium_impact	2,66	damaging	0,2	damaging	0,04	deleterious	3,88	23,5	0,29	0,45	neutral	0,42	disease	0,71	disease	0,73	disease	0,67	3	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,79	low_impact	-2,58	medium_impact	-0,23	medium_impact	1,39	0,75	0,85	67,4	19,68	P	0,89	P	0,81	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7913	7913	T	A	MI.5887	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	328	110	Y	N	Tac/Aac	-2,01	0	0	probably_damaging	1	neutral	0,13	neutral	1,47	deleterious	-6,9	deleterious	-8,8	high_impact	3,7	damaging	0,35	damaging	0,03	deleterious	4,27	24	0,28	0,45	disease	0,84	disease	0,89	disease	0,73	disease	0,65	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	-0,25	high_impact	2,36	0,19	0,8	69,16	19,05	N	0,48	N	0,99	disease_causing	0,56	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7913	7913	T	G	MI.5888	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	328	110	Y	D	Tac/Gac	-2,01	0	0	probably_damaging	1	neutral	0,08	neutral	1,46	deleterious	-7,44	deleterious	-9,75	high_impact	4,05	damaging	0,34	damaging	0,03	deleterious	4,04	23,7	0,17	0,45	disease	0,92	disease	0,85	disease	0,76	disease	0,61	2	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	-0,38	high_impact	2,69	0,25	0,8	69,16	19,05	N	0,48	N	0,99	polymorphism	0,52	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7913	7913	T	C	MI.5889	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	328	110	Y	H	Tac/Cac	-2,01	0	0	probably_damaging	1	neutral	0,2	neutral	1,47	deleterious	-5,85	deleterious	-4,92	high_impact	3,5	damaging	0,33	damaging	0,02	deleterious	3,66	23,2	0,33	0,5	disease	0,79	disease	0,78	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,13	high_impact	2,18	0,33	0,8	69,16	19,05	N	0,45	N	0,94	polymorphism	0,9	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8803	8803	A	T	MI.589	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	277	93	T	S	Aca/Tca	-5,89	0	0,01	probably_damaging	0,99	neutral	0,17	neutral	4,15	neutral	-2,53	deleterious	-3,46	medium_impact	2,08	neutral	0,6	neutral	0,54	deleterious	3,17	22,7	0,46	0,65	disease	0,52	neutral	0,35	disease	0,59	neutral	0,45	1	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,71	low_impact	-2,65	medium_impact	-0,1	medium_impact	0,69	0,57	0,9	46,02	8,31	N	0,37	N	0,88	polymorphism	0,95	0,11	rs878853020	Uncertain significance	not_provided	RCV000224874.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	7914	7914	A	G	MI.5890	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	329	110	Y	C	tAc/tGc	5,83	1	0	probably_damaging	1	neutral	0,06	neutral	1,45	deleterious	-7,7	deleterious	-8,75	high_impact	3,85	damaging	0,27	damaging	0,03	deleterious	3,62	23,2	0,28	0,45	disease	0,95	disease	0,89	disease	0,76	disease	0,63	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	-0,46	high_impact	2,5	0,22	0,8	69,16	19,05	P	0,74	P	0,96	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7914	7914	A	C	MI.5891	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	329	110	Y	S	tAc/tCc	5,83	1	0	probably_damaging	1	neutral	0,28	neutral	1,48	deleterious	-6,02	deleterious	-8,75	high_impact	3,85	damaging	0,33	damaging	0,05	deleterious	3,82	23,4	0,24	0,45	disease	0,85	disease	0,82	disease	0,72	disease	0,63	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,02	high_impact	2,5	0,26	0,8	69,16	19,05	P	0,63	P	0,99	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7914	7914	A	T	MI.5892	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	329	110	Y	F	tAc/tTc	5,83	1	0	probably_damaging	1	neutral	0,28	neutral	1,61	deleterious	-4,55	deleterious	-3,63	medium_impact	2,42	damaging	0,48	neutral	0,39	deleterious	2,39	18,77	0,26	0,45	disease	0,77	disease	0,78	disease	0,65	neutral	0,39	2	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,87	low_impact	-3,52	medium_impact	-0,02	medium_impact	1,16	0,44	0,8	69,16	19,05	P	0,63	P	0,87	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7916	7916	A	G	MI.5893	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	331	111	T	A	Acc/Gcc	-2,94	0	0	probably_damaging	0,99	neutral	0,55	neutral	2,01	neutral	0,46	deleterious	-3,66	low_impact	1,21	neutral	0,64	neutral	0,52	deleterious	3,38	22,9	0,44	0,55	neutral	0,34	disease	0,55	neutral	0,49	neutral	0,38	2	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,74	low_impact	-2,58	medium_impact	0,25	medium_impact	0,03	0,51	0,8	68,28	16,39	N	0,27	N	0,65	polymorphism	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7916	7916	A	T	MI.5894	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	331	111	T	S	Acc/Tcc	-2,94	0	0	probably_damaging	0,99	neutral	0,66	neutral	2,09	neutral	0,45	neutral	-2,4	neutral_impact	-1,07	neutral	0,61	neutral	0,77	neutral	1,51	13,38	0,41	0,5	neutral	0,21	neutral	0,03	neutral	0,21	neutral	0,23	5	deleterious	0,99	neutral	0,34	neutral	-2	deleterious	0,66	low_impact	-2,58	medium_impact	0,36	low_impact	-2,11	0,46	0,8	68,28	16,39	N	0,33	N	0,8	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7916	7916	A	C	MI.5895	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	331	111	T	P	Acc/Ccc	-2,94	0	0	probably_damaging	1	neutral	0,27	neutral	2,13	neutral	2,04	deleterious	-5	neutral_impact	0,3	damaging	0,43	neutral	0,3	deleterious	3,48	23,1	0,39	0,5	neutral	0,17	disease	0,83	disease	0,53	disease	0,55	1	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,77	low_impact	-3,52	medium_impact	-0,03	medium_impact	-0,82	0,57	0,8	68,28	16,39	N	0,39	N	0,9	polymorphism	0,95	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7917	7917	C	G	MI.5896	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	332	111	T	S	aCc/aGc	6,75	1	0	probably_damaging	0,99	neutral	0,66	neutral	2,09	neutral	0,45	neutral	-2,4	neutral_impact	-1,07	neutral	0,61	neutral	0,77	deleterious	1,83	15,15	0,41	0,5	neutral	0,21	neutral	0,03	neutral	0,21	neutral	0,23	5	deleterious	0,99	neutral	0,34	neutral	-2	deleterious	0,66	low_impact	-2,58	medium_impact	0,36	low_impact	-2,11	0,46	0,8	68,28	16,39	P	0,51	P	0,8	disease_causing	0,83	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7917	7917	C	A	MI.5897	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	332	111	T	N	aCc/aAc	6,75	1	0	probably_damaging	1	neutral	0,34	neutral	1,96	neutral	-0,68	deleterious	-3,86	neutral_impact	0,59	damaging	0,5	neutral	0,34	deleterious	3,72	23,3	0,55	0,6	neutral	0,36	disease	0,83	neutral	0,5	disease	0,69	4	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,78	low_impact	-3,52	medium_impact	0,05	medium_impact	-0,55	0,62	0,8	68,28	16,39	N	0,47	N	0,87	disease_causing	0,98	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7917	7917	C	T	MI.5898	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	332	111	T	I	aCc/aTc	6,75	1	0	probably_damaging	1	neutral	0,42	neutral	2,05	neutral	-0,77	deleterious	-5,19	low_impact	1,38	damaging	0,51	neutral	0,44	deleterious	4,04	23,7	0,5	0,6	disease	0,59	disease	0,73	disease	0,57	disease	0,68	4	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,83	low_impact	-3,52	medium_impact	0,13	medium_impact	0,19	0,54	0,8	68,28	16,39	N	0,48	N	0,77	disease_causing	0,98	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7919	7919	G	A	MI.5899	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	334	112	D	N	Gac/Aac	-5,93	0	0	probably_damaging	1	neutral	0,35	neutral	1,59	neutral	-2,16	deleterious	-4,55	medium_impact	2,04	damaging	0,5	neutral	0,51	deleterious	4,16	23,8	0,69	0,75	neutral	0,46	disease	0,8	disease	0,59	neutral	0,34	3	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,78	low_impact	-3,52	medium_impact	0,06	medium_impact	0,81	0,68	0,85	67,84	19,4	N	0,38	N	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8552	8552	T	C	MI.59	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	26	9	F	S	tTc/tCc	7,53	1	0	probably_damaging	0,97	deleterious	0	neutral	3,85	neutral	-2,62	deleterious	-7	medium_impact	3,24	neutral	0,63	neutral	0,73	deleterious	4,04	23,7	0,43	0,65	disease	0,66	disease	0,84	disease	0,83	disease	0,84	7	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,82	low_impact	-2,19	low_impact	-1,4	medium_impact	1,68	0,39	0,9	49,56	8,77	P	0,6	P	0,99	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8803	8803	A	C	MI.590	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	277	93	T	P	Aca/Cca	-5,89	0	0,01	probably_damaging	1	neutral	0,05	neutral	4,14	neutral	-2,87	deleterious	-5,37	medium_impact	3,22	damaging	0,53	neutral	0,41	deleterious	3,47	23	0,18	0,65	disease	0,71	disease	0,67	disease	0,59	disease	0,63	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	-0,43	medium_impact	1,66	0,5	0,9	46,02	8,31	N	0,35	N	0,99	polymorphism	0,56	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7919	7919	G	T	MI.5900	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	334	112	D	Y	Gac/Tac	-5,93	0	0	probably_damaging	1	neutral	0,71	neutral	1,47	deleterious	-5,38	deleterious	-8,7	high_impact	3,88	damaging	0,43	damaging	0,22	deleterious	3,92	23,5	0,28	0,45	disease	0,92	disease	0,91	disease	0,68	disease	0,59	2	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,42	high_impact	2,53	0,35	0,8	67,84	19,4	N	0,41	N	0,99	polymorphism	0,98	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7919	7919	G	C	MI.5901	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	334	112	D	H	Gac/Cac	-5,93	0	0	probably_damaging	1	neutral	0,29	neutral	1,49	deleterious	-4,35	deleterious	-6,67	high_impact	3,88	damaging	0,43	damaging	0,23	deleterious	3,67	23,3	0,53	0,6	disease	0,86	disease	0,77	disease	0,73	disease	0,64	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,01	high_impact	2,53	0,65	0,8	67,84	19,4	N	0,43	N	0,98	polymorphism	0,99	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7920	7920	A	G	MI.5902	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	335	112	D	G	gAc/gGc	6,06	1	0	probably_damaging	1	neutral	0,37	neutral	1,51	deleterious	-3,52	deleterious	-6,7	medium_impact	2,68	damaging	0,46	neutral	0,34	deleterious	4,14	23,8	0,51	0,6	neutral	0,44	disease	0,79	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,77	low_impact	-3,52	medium_impact	0,08	medium_impact	1,41	0,46	0,8	67,84	19,4	P	0,54	P	0,97	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7920	7920	A	C	MI.5903	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	335	112	D	A	gAc/gCc	6,06	1	0	probably_damaging	1	neutral	0,51	neutral	1,53	deleterious	-3,09	deleterious	-7,75	medium_impact	3,23	damaging	0,46	neutral	0,36	deleterious	3,78	23,4	0,37	0,5	disease	0,75	disease	0,81	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,84	low_impact	-3,52	medium_impact	0,21	medium_impact	1,92	0,66	0,8	67,84	19,4	P	0,56	P	0,96	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7920	7920	A	T	MI.5904	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	335	112	D	V	gAc/gTc	6,06	1	0	probably_damaging	1	neutral	0,36	neutral	1,48	deleterious	-4,52	deleterious	-8,74	high_impact	3,73	damaging	0,4	damaging	0,24	deleterious	3,94	23,5	0,31	0,45	disease	0,88	disease	0,87	disease	0,7	disease	0,62	2	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	0,07	high_impact	2,39	0,4	0,8	67,84	19,4	P	0,71	P	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7921	7921	C	G	MI.5905	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	336	112	D	E	gaC/gaG	8,59	1	0	probably_damaging	1	neutral	0,72	neutral	1,65	neutral	-1,68	deleterious	-3,85	medium_impact	2,46	damaging	0,43	damaging	0,22	deleterious	3,95	23,6	0,58	0,65	disease	0,59	disease	0,74	disease	0,57	disease	0,64	3	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	0,43	medium_impact	1,2	0,71	0,85	67,84	19,4	P	0,69	P	0,95	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7921	7921	C	A	MI.5906	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	336	112	D	E	gaC/gaA	8,59	1	0	probably_damaging	1	neutral	0,72	neutral	1,65	neutral	-1,68	deleterious	-3,85	medium_impact	2,46	damaging	0,43	damaging	0,22	deleterious	4,2	23,9	0,58	0,65	disease	0,59	disease	0,74	disease	0,57	disease	0,64	3	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	0,43	medium_impact	1,2	0,71	0,85	67,84	19,4	P	0,7	P	0,95	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7922	7922	T	A	MI.5907	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	337	113	Y	N	Tac/Aac	-2,24	0	0	benign	0,43	neutral	0,31	neutral	1,91	neutral	-1,68	deleterious	-8,33	low_impact	1,77	damaging	0,58	neutral	0,4	deleterious	2,68	20,7	0,6	0,65	disease	0,67	disease	0,9	disease	0,56	disease	0,69	4	neutral	0,64	neutral	0,44	neutral	-6	deleterious	0,64	medium_impact	-0,61	medium_impact	0,01	medium_impact	0,55	0,23	0,8	69,6	18,98	N	0,32	N	0,99	polymorphism	0,54	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7922	7922	T	G	MI.5908	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	337	113	Y	D	Tac/Gac	-2,24	0	0	possibly_damaging	0,6	neutral	0,21	neutral	1,93	neutral	-1,15	deleterious	-9,16	low_impact	1,75	damaging	0,53	neutral	0,33	deleterious	3,82	23,4	0,53	0,6	disease	0,73	disease	0,88	disease	0,61	disease	0,72	4	neutral	0,79	neutral	0,31	neutral	-3	deleterious	0,74	medium_impact	-0,89	medium_impact	-0,11	medium_impact	0,54	0,36	0,8	69,6	18,98	N	0,33	N	0,99	polymorphism	0,62	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7922	7922	T	C	MI.5909	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	337	113	Y	H	Tac/Cac	-2,24	0	0	benign	0,01	neutral	0,47	neutral	1,9	neutral	-2,1	deleterious	-4,76	low_impact	1,8	neutral	0,66	neutral	0,34	neutral	1,69	14,37	0,66	0,7	disease	0,75	disease	0,69	neutral	0,46	neutral	0,47	1	neutral	0,51	deleterious	0,73	neutral	-6	neutral	0,3	medium_impact	1,14	medium_impact	0,18	medium_impact	0,58	0,23	0,8	69,6	18,98	N	0,27	N	0,94	polymorphism	0,93	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8803	8803	A	G	MI.591	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	277	93	T	A	Aca/Gca	-5,89	0	0,01	probably_damaging	0,99	deleterious	0,03	neutral	4,24	neutral	-1,13	deleterious	-4,24	medium_impact	2,43	neutral	0,81	neutral	0,58	deleterious	3,42	23	0,48	0,65	neutral	0,32	neutral	0,37	neutral	0,5	neutral	0,4	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,68	low_impact	-2,65	medium_impact	-0,56	medium_impact	0,99	0,5	0,9	46,02	8,31	N	0,4	N	0,63	polymorphism	0,87	0,12	.	.	.	.	.	head/neck tumor	.	.	.	.	.	.	.	.	.
chrM	7923	7923	A	G	MI.5910	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	338	113	Y	C	tAc/tGc	5,83	1	0	probably_damaging	0,91	neutral	0,16	neutral	1,89	neutral	-2,78	deleterious	-8,06	medium_impact	2,74	damaging	0,59	neutral	0,29	deleterious	3,58	23,2	0,58	0,65	disease	0,78	disease	0,9	disease	0,58	disease	0,69	4	neutral	0,95	neutral	0,13	deleterious	1	deleterious	0,82	low_impact	-1,66	medium_impact	-0,19	medium_impact	1,46	0,12	0,8	69,6	18,98	N	0,46	N	0,96	disease_causing	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7923	7923	A	T	MI.5911	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	338	113	Y	F	tAc/tTc	5,83	1	0	benign	0,19	neutral	0,86	neutral	2,1	neutral	0,86	deleterious	-2,82	neutral_impact	-0,16	neutral	0,71	neutral	0,84	neutral	-0,15	1,4	0,57	0,65	neutral	0,39	neutral	0,1	neutral	0,17	neutral	0,29	4	neutral	0,09	deleterious	0,84	neutral	-6	neutral	0,37	medium_impact	-0,13	medium_impact	0,64	low_impact	-1,26	0,28	0,8	69,6	18,98	P	0,49	N	0,87	disease_causing	0,78	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7923	7923	A	C	MI.5912	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	338	113	Y	S	tAc/tCc	5,83	1	0	possibly_damaging	0,52	neutral	0,42	neutral	1,94	neutral	-0,87	deleterious	-8,12	low_impact	1,52	damaging	0,58	neutral	0,46	deleterious	3,38	22,9	0,54	0,6	neutral	0,44	disease	0,79	neutral	0,48	disease	0,56	1	neutral	0,57	neutral	0,45	neutral	-3	deleterious	0,61	medium_impact	-0,75	medium_impact	0,13	medium_impact	0,32	0,23	0,8	69,6	18,98	P	0,49	N	0,99	disease_causing	0,98	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7925	7925	G	T	MI.5913	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	340	114	G	C	Ggc/Tgc	-1,55	0	0	probably_damaging	0,99	neutral	0,09	neutral	1,78	deleterious	-5,34	neutral	-1,59	low_impact	1,84	neutral	0,63	neutral	0,44	deleterious	4,13	23,8	0,2	0,45	disease	0,79	disease	0,65	neutral	0,19	neutral	0,4	2	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,78	low_impact	-2,58	medium_impact	-0,35	medium_impact	0,62	0,35	0,8	29,07	71,47	N	0,42	N	0,75	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7925	7925	G	C	MI.5914	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	340	114	G	R	Ggc/Cgc	-1,55	0	0	probably_damaging	0,94	neutral	0,4	neutral	1,83	neutral	-1,89	neutral	1,15	low_impact	1,64	neutral	0,65	neutral	0,45	deleterious	2,81	21,4	0,33	0,5	disease	0,53	disease	0,65	neutral	0,37	neutral	0,41	2	neutral	0,95	neutral	0,23	neutral	-2	deleterious	0,74	low_impact	-1,83	medium_impact	0,11	medium_impact	0,43	0,75	0,85	29,07	71,47	N	0,37	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7925	7925	G	A	MI.5915	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	340	114	G	S	Ggc/Agc	-1,55	0	0	possibly_damaging	0,82	neutral	0,85	neutral	1,86	neutral	-1,4	neutral	1,39	neutral_impact	0,48	neutral	0,79	neutral	0,82	deleterious	2,68	20,7	0,42	0,55	neutral	0,44	neutral	0,22	neutral	0,11	neutral	0,43	1	neutral	0,79	deleterious	0,52	neutral	-3	deleterious	0,62	low_impact	-1,33	medium_impact	0,62	medium_impact	-0,66	0,73	0,85	29,07	71,47	N	0,27	N	0,39	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7926	7926	G	C	MI.5916	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	341	114	G	A	gGc/gCc	0,52	0,03	0	possibly_damaging	0,73	neutral	0,64	neutral	1,85	neutral	-1,25	neutral	0,54	neutral_impact	0,56	neutral	0,75	neutral	0,76	neutral	1,71	14,48	0,43	0,55	neutral	0,42	neutral	0,28	neutral	0,19	neutral	0,45	1	neutral	0,68	neutral	0,46	neutral	-3	deleterious	0,6	low_impact	-1,12	medium_impact	0,34	medium_impact	-0,58	0,59	0,8	29,07	71,47	N	0,38	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7926	7926	G	A	MI.5917	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	341	114	G	D	gGc/gAc	0,52	0,03	0	possibly_damaging	0,82	neutral	0,83	neutral	1,88	neutral	-0,27	neutral	1,83	neutral_impact	-0,13	neutral	0,77	neutral	0,94	deleterious	2,26	17,87	0,31	0,45	disease	0,57	disease	0,55	neutral	0,31	neutral	0,24	5	neutral	0,79	deleterious	0,51	neutral	-3	deleterious	0,68	low_impact	-1,33	medium_impact	0,59	low_impact	-1,23	0,53	0,8	29,07	71,47	N	0,23	N	0,44	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7926	7926	G	T	MI.5918	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	341	114	G	V	gGc/gTc	0,52	0,03	0	probably_damaging	0,97	neutral	0,39	neutral	1,84	neutral	-2,87	neutral	-0,25	neutral_impact	0,52	neutral	0,78	neutral	0,79	deleterious	2,66	20,5	0,28	0,45	neutral	0,28	neutral	0,47	neutral	0,25	neutral	0,45	1	neutral	0,97	neutral	0,21	neutral	-2	deleterious	0,65	low_impact	-2,13	medium_impact	0,1	medium_impact	-0,62	0,35	0,8	29,07	71,47	N	0,35	N	0,79	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7928	7928	G	C	MI.5919	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	343	115	G	R	Gga/Cga	-0,4	0,02	0	probably_damaging	0,94	neutral	0,63	neutral	2,01	neutral	0,14	neutral	-0,61	low_impact	1,75	neutral	0,63	neutral	0,44	deleterious	3,98	23,6	0,52	0,6	neutral	0,39	disease	0,76	disease	0,64	disease	0,68	4	neutral	0,93	neutral	0,35	neutral	-2	deleterious	0,74	low_impact	-1,83	medium_impact	0,33	medium_impact	0,54	0,84	0,9	27,75	74,03	N	0,27	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8804	8804	C	A	MI.592	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	278	93	T	K	aCa/aAa	6,84	1	0	probably_damaging	1	deleterious	0,01	neutral	4,13	deleterious	-3,08	deleterious	-5,32	high_impact	4,07	neutral	0,62	neutral	0,39	deleterious	4,32	24	0,21	0,65	disease	0,83	disease	0,71	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,6	medium_impact	-0,84	high_impact	2,39	0,65	0,9	46,02	8,31	P	0,54	P	1	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7928	7928	G	T	MI.5920	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	343	115	G	W	Gga/Tga	-0,4	0,02	0	probably_damaging	0,99	neutral	0,22	neutral	1,93	deleterious	-3,7	deleterious	-3,02	medium_impact	2,56	neutral	0,68	neutral	0,46	deleterious	4,56	24,4	0,33	0,5	disease	0,88	disease	0,76	disease	0,63	disease	0,73	5	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,83	low_impact	-2,58	medium_impact	-0,1	medium_impact	1,3	0,43	0,8	27,75	74,03	N	0,27	N	0,48	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7929	7929	G	A	MI.5921	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	344	115	G	E	gGa/gAa	1,68	0,96	0	possibly_damaging	0,82	neutral	0,85	neutral	2,08	neutral	1,12	neutral	2	neutral_impact	0,77	neutral	0,82	neutral	0,86	deleterious	2,53	19,68	0,53	0,6	neutral	0,29	disease	0,63	neutral	0,39	neutral	0,23	6	neutral	0,8	deleterious	0,52	neutral	-3	deleterious	0,67	low_impact	-1,33	medium_impact	0,62	medium_impact	-0,38	0,43	0,8	27,75	74,03	N	0,28	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7929	7929	G	C	MI.5922	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	344	115	G	A	gGa/gCa	1,68	0,96	0	possibly_damaging	0,5	neutral	0,95	neutral	2,03	neutral	0,55	neutral	-0,97	low_impact	1,41	neutral	0,74	neutral	0,78	deleterious	2,72	20,9	0,51	0,6	neutral	0,35	neutral	0,37	neutral	0,37	neutral	0,46	1	neutral	0,45	deleterious	0,73	neutral	-3	deleterious	0,52	medium_impact	-0,72	medium_impact	0,91	medium_impact	0,22	0,57	0,8	27,75	74,03	N	0,34	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7929	7929	G	T	MI.5923	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	344	115	G	V	gGa/gTa	1,68	0,96	0	probably_damaging	0,94	neutral	0,66	neutral	1,99	neutral	-0,31	neutral	-2,04	low_impact	1,52	neutral	0,73	neutral	0,6	deleterious	3,74	23,3	0,44	0,55	disease	0,54	disease	0,6	disease	0,53	disease	0,59	2	neutral	0,93	neutral	0,36	neutral	-2	deleterious	0,73	low_impact	-1,83	medium_impact	0,36	medium_impact	0,32	0,37	0,8	27,75	74,03	N	0,3	N	0,42	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7931	7931	C	G	MI.5924	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	346	116	L	V	Cta/Gta	-1,55	0	0	probably_damaging	0,99	neutral	0,52	neutral	2,02	neutral	0,1	neutral	-2,49	low_impact	1,07	damaging	0,37	damaging	0,08	deleterious	2,32	18,3	0,56	0,6	neutral	0,42	neutral	0,18	neutral	0,22	neutral	0,31	4	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,68	low_impact	-2,58	medium_impact	0,22	medium_impact	-0,1	0,67	0,85	68,72	19,34	N	0,46	N	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7931	7931	C	A	MI.5925	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	346	116	L	M	Cta/Ata	-1,55	0	0	probably_damaging	1	neutral	0,22	neutral	1,78	neutral	-2,11	neutral	-1,47	low_impact	1,32	damaging	0,4	damaging	0,25	deleterious	2,69	20,7	0,33	0,5	disease	0,67	neutral	0,25	neutral	0,23	disease	0,56	1	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,73	low_impact	-3,52	medium_impact	-0,1	medium_impact	0,13	0,77	0,85	68,72	19,34	P	0,54	P	0,78	polymorphism	1	0,02	rs28705169	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7932	7932	T	G	MI.5926	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	347	116	L	R	cTa/cGa	-2,01	0	0	probably_damaging	1	neutral	0,35	neutral	1,73	deleterious	-3,56	deleterious	-5,59	medium_impact	3,31	damaging	0,16	damaging	0,02	deleterious	4,23	23,9	0,4	0,5	disease	0,78	disease	0,81	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,88	low_impact	-3,52	medium_impact	0,06	medium_impact	2	0,54	0,8	68,72	19,34	P	0,75	P	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7932	7932	T	C	MI.5927	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	347	116	L	P	cTa/cCa	-2,01	0	0	probably_damaging	1	neutral	0,22	neutral	1,72	deleterious	-4,25	deleterious	-6,46	medium_impact	2,27	damaging	0,11	damaging	0,03	deleterious	3,99	23,6	0,38	0,5	disease	0,84	disease	0,79	disease	0,57	disease	0,68	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,89	low_impact	-3,52	medium_impact	-0,1	medium_impact	1,02	0,48	0,8	68,72	19,34	P	0,72	P	0,99	polymorphism	0,98	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7932	7932	T	A	MI.5928	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	347	116	L	Q	cTa/cAa	-2,01	0	0	probably_damaging	1	neutral	0,31	neutral	1,73	deleterious	-3,62	deleterious	-5,45	medium_impact	2,62	damaging	0,32	damaging	0,05	deleterious	4,26	23,9	0,46	0,55	disease	0,8	disease	0,56	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,83	low_impact	-3,52	medium_impact	0,01	medium_impact	1,35	0,58	0,8	68,72	19,34	P	0,51	P	0,95	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7934	7934	A	T	MI.5929	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	349	117	I	F	Atc/Ttc	-10,08	0	0	benign	0,38	neutral	0,7	neutral	1,98	neutral	-1,15	neutral	-0,47	neutral_impact	0,2	neutral	0,71	neutral	0,69	deleterious	2,21	17,59	0,53	0,6	neutral	0,4	disease	0,61	neutral	0,49	neutral	0,45	1	neutral	0,29	deleterious	0,66	neutral	-6	neutral	0,41	medium_impact	-0,52	medium_impact	0,41	medium_impact	-0,92	0,48	0,8	32,16	56,45	N	0,24	N	0,32	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8804	8804	C	T	MI.593	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	278	93	T	M	aCa/aTa	6,84	1	0	probably_damaging	1	deleterious	0	neutral	4,14	neutral	-2,84	deleterious	-5,32	high_impact	4,42	neutral	0,7	neutral	0,53	deleterious	3,94	23,5	0,32	0,65	disease	0,91	disease	0,63	disease	0,7	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,6	low_impact	-1,4	high_impact	2,69	0,7	0,9	46,02	8,31	P	0,56	P	0,98	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7934	7934	A	G	MI.5930	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	349	117	I	V	Atc/Gtc	-10,08	0	0	benign	0	neutral	0,5	neutral	2,01	neutral	0,24	neutral	0,57	neutral_impact	0,38	neutral	0,85	neutral	0,93	deleterious	-0,04	2,24	0,67	0,7	neutral	0,15	neutral	0,27	neutral	0,46	neutral	0,37	3	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,09	high_impact	2,08	medium_impact	0,21	medium_impact	-0,75	0,52	0,8	32,16	56,45	N	0,3	N	0,34	polymorphism	1	0	rs374261450	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7934	7934	A	C	MI.5931	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	349	117	I	L	Atc/Ctc	-10,08	0	0	benign	0,04	neutral	0,65	neutral	2,01	neutral	0,32	neutral	-0,01	neutral_impact	0,16	neutral	0,69	neutral	0,63	deleterious	0,67	8,63	0,52	0,6	neutral	0,22	neutral	0,46	neutral	0,44	neutral	0,43	1	neutral	0,29	deleterious	0,81	neutral	-6	neutral	0,14	medium_impact	0,57	medium_impact	0,35	medium_impact	-0,96	0,42	0,8	32,16	56,45	N	0,36	N	0,33	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7935	7935	T	A	MI.5932	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	350	117	I	N	aTc/aAc	-0,86	0	0	possibly_damaging	0,8	neutral	0,31	neutral	2,04	neutral	0,87	neutral	1,69	neutral_impact	-0,41	neutral	0,74	neutral	0,94	deleterious	2,99	22,2	0,49	0,55	neutral	0,29	disease	0,73	neutral	0,38	neutral	0,22	6	neutral	0,83	neutral	0,26	neutral	-3	deleterious	0,59	low_impact	-1,28	medium_impact	0,01	low_impact	-1,49	0,55	0,8	32,16	56,45	N	0,32	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7935	7935	T	G	MI.5933	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	350	117	I	S	aTc/aGc	-0,86	0	0	possibly_damaging	0,46	neutral	0,4	neutral	2,11	neutral	1,8	neutral	2,31	neutral_impact	-1,58	neutral	0,75	neutral	0,95	deleterious	0,64	8,46	0,38	0,5	neutral	0,2	neutral	0,49	neutral	0,23	neutral	0,28	4	neutral	0,56	deleterious	0,47	neutral	-3	neutral	0,26	medium_impact	-0,66	medium_impact	0,11	low_impact	-2,59	0,42	0,8	32,16	56,45	N	0,33	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7935	7935	T	C	MI.5934	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	350	117	I	T	aTc/aCc	-0,86	0	0	benign	0,2	neutral	0,39	neutral	2,05	neutral	1,03	neutral	2,06	neutral_impact	-0,92	neutral	0,76	neutral	0,94	deleterious	0	2,55	0,6	0,65	neutral	0,13	neutral	0,37	neutral	0,23	neutral	0,4	2	neutral	0,53	deleterious	0,6	neutral	-6	neutral	0,16	medium_impact	-0,16	medium_impact	0,1	low_impact	-1,97	0,42	0,8	32,16	56,45	N	0,31	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7936	7936	C	G	MI.5935	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	351	117	I	M	atC/atG	-2,48	0	0	possibly_damaging	0,66	neutral	0,22	neutral	1,98	neutral	-0,87	neutral	0,62	neutral_impact	-0,09	neutral	0,72	neutral	0,9	deleterious	2	16,19	0,64	0,7	neutral	0,39	neutral	0,35	neutral	0,19	neutral	0,44	1	neutral	0,81	neutral	0,28	neutral	-3	neutral	0,4	medium_impact	-0,99	medium_impact	-0,1	low_impact	-1,19	0,72	0,85	32,16	56,45	N	0,53	P	0,52	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7936	7936	C	A	MI.5936	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	351	117	I	M	atC/atA	-2,48	0	0	possibly_damaging	0,66	neutral	0,22	neutral	1,98	neutral	-0,87	neutral	0,62	neutral_impact	-0,09	neutral	0,72	neutral	0,9	deleterious	2,41	18,91	0,64	0,7	neutral	0,39	neutral	0,35	neutral	0,19	neutral	0,44	1	neutral	0,81	neutral	0,28	neutral	-3	neutral	0,4	medium_impact	-0,99	medium_impact	-0,1	low_impact	-1,19	0,72	0,85	32,16	56,45	N	0,53	P	0,52	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7937	7937	T	C	MI.5937	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	352	118	F	L	Ttc/Ctc	-2,71	0	0	probably_damaging	1	neutral	0,67	neutral	1,58	neutral	-1,78	deleterious	-5,56	medium_impact	3,04	damaging	0,32	neutral	0,54	deleterious	4,14	23,8	0,46	0,55	neutral	0,46	disease	0,84	disease	0,72	disease	0,69	4	deleterious	0,99	neutral	0,34	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	0,38	medium_impact	1,75	0,5	0,8	67,84	19,52	P	0,67	P	0,81	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7937	7937	T	A	MI.5938	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	352	118	F	I	Ttc/Atc	-2,71	0	0	probably_damaging	1	neutral	0,4	neutral	1,5	neutral	-2,5	deleterious	-5,63	medium_impact	2,36	damaging	0,32	neutral	0,52	deleterious	4,46	24,2	0,37	0,5	disease	0,54	disease	0,81	disease	0,72	disease	0,58	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,82	low_impact	-3,52	medium_impact	0,11	medium_impact	1,11	0,44	0,8	67,84	19,52	P	0,64	P	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7937	7937	T	G	MI.5939	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	352	118	F	V	Ttc/Gtc	-2,71	0	0	probably_damaging	1	neutral	0,5	neutral	1,47	neutral	-2,82	deleterious	-6,62	medium_impact	2,83	damaging	0,32	neutral	0,43	deleterious	4,16	23,8	0,33	0,5	neutral	0,39	disease	0,88	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,79	low_impact	-3,52	medium_impact	0,21	medium_impact	1,55	0,42	0,8	67,84	19,52	P	0,67	P	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8806	8806	C	G	MI.594	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	280	94	P	A	Cca/Gca	-8,43	0	0	probably_damaging	1	neutral	0,13	neutral	3,67	neutral	-1,42	deleterious	-7,2	medium_impact	2,19	neutral	0,78	damaging	0,22	deleterious	3,03	22,3	0,3	0,65	disease	0,64	neutral	0,37	disease	0,54	disease	0,61	2	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,18	medium_impact	0,78	0,86	0,9	49,56	8,53	N	0,3	N	0,79	polymorphism	0,82	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7938	7938	T	C	MI.5940	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	353	118	F	S	tTc/tCc	4,67	1	0	probably_damaging	1	neutral	0,44	neutral	1,4	deleterious	-4,46	deleterious	-7,69	high_impact	4,08	damaging	0,37	neutral	0,52	deleterious	4,35	24,1	0,28	0,45	disease	0,65	disease	0,85	disease	0,79	disease	0,69	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	0,15	high_impact	2,72	0,31	0,8	67,84	19,52	P	0,77	P	0,96	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7938	7938	T	A	MI.5941	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	353	118	F	Y	tTc/tAc	4,67	1	0	probably_damaging	1	neutral	1	neutral	1,47	neutral	-2,84	deleterious	-2,89	low_impact	1,87	damaging	0,35	neutral	0,41	deleterious	4,33	24	0,34	0,5	neutral	0,41	disease	0,76	disease	0,71	disease	0,57	1	deleterious	0,99	deleterious	0,5	neutral	-2	deleterious	0,79	low_impact	-3,52	high_impact	1,86	medium_impact	0,65	0,56	0,8	67,84	19,52	P	0,72	P	0,76	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7938	7938	T	G	MI.5942	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	353	118	F	C	tTc/tGc	4,67	1	0	probably_damaging	1	neutral	0,18	neutral	1,37	deleterious	-5,94	deleterious	-7,66	high_impact	4,08	damaging	0,3	neutral	0,44	deleterious	4,19	23,8	0,28	0,45	disease	0,83	disease	0,86	disease	0,8	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,16	high_impact	2,72	0,25	0,8	67,84	19,52	P	0,76	P	1	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7939	7939	C	A	MI.5943	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	354	118	F	L	ttC/ttA	5,83	1	0	probably_damaging	1	neutral	0,67	neutral	1,58	neutral	-1,78	deleterious	-5,56	medium_impact	3,04	damaging	0,32	neutral	0,54	deleterious	4,75	24,7	0,46	0,55	neutral	0,46	disease	0,84	disease	0,72	disease	0,69	4	deleterious	0,99	neutral	0,34	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	0,38	medium_impact	1,75	0,5	0,8	67,84	19,52	P	0,81	P	0,81	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7939	7939	C	G	MI.5944	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	354	118	F	L	ttC/ttG	5,83	1	0	probably_damaging	1	neutral	0,67	neutral	1,58	neutral	-1,78	deleterious	-5,56	medium_impact	3,04	damaging	0,32	neutral	0,54	deleterious	4,44	24,2	0,46	0,55	neutral	0,46	disease	0,84	disease	0,72	disease	0,69	4	deleterious	0,99	neutral	0,34	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	0,38	medium_impact	1,75	0,5	0,8	67,84	19,52	P	0,81	P	0,81	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7940	7940	A	G	MI.5945	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	355	119	N	D	Aac/Gac	-3,17	0	0	probably_damaging	0,99	neutral	1	neutral	2,47	neutral	2,44	neutral	4,57	neutral_impact	-2,04	neutral	0,76	neutral	0,93	neutral	1,15	11,49	0,76	0,8	neutral	0,21	neutral	0,03	neutral	0,28	neutral	0,15	7	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,64	low_impact	-2,58	high_impact	1,86	low_impact	-3,02	0,55	0,8	28,63	71,46	N	0,28	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7940	7940	A	C	MI.5946	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	355	119	N	H	Aac/Cac	-3,17	0	0	probably_damaging	1	neutral	0,38	neutral	1,9	neutral	-2,07	neutral	-2,07	medium_impact	2,04	neutral	0,75	neutral	0,55	deleterious	3,12	22,6	0,51	0,6	neutral	0,14	neutral	0,29	disease	0,71	neutral	0,39	2	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,7	low_impact	-3,52	medium_impact	0,09	medium_impact	0,81	0,33	0,8	28,63	71,46	N	0,33	N	0,44	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7940	7940	A	T	MI.5947	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	355	119	N	Y	Aac/Tac	-3,17	0	0	probably_damaging	1	neutral	0,92	neutral	1,89	deleterious	-3,15	deleterious	-4,09	low_impact	1	neutral	0,72	neutral	0,63	deleterious	3,77	23,4	0,35	0,5	disease	0,51	neutral	0,43	disease	0,71	disease	0,51	0	deleterious	1	neutral	0,46	neutral	-2	deleterious	0,78	low_impact	-3,52	medium_impact	0,79	medium_impact	-0,17	0,46	0,8	28,63	71,46	N	0,23	N	0,86	polymorphism	0,97	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7941	7941	A	G	MI.5948	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	356	119	N	S	aAc/aGc	6,06	1	0	probably_damaging	0,99	neutral	0,59	neutral	1,95	neutral	-0,68	neutral	-1,12	low_impact	1,14	neutral	0,75	neutral	0,65	deleterious	3,15	22,6	0,7	0,75	neutral	0,2	neutral	0,28	disease	0,58	neutral	0,39	2	deleterious	0,99	neutral	0,3	neutral	-2	deleterious	0,71	low_impact	-2,58	medium_impact	0,29	medium_impact	-0,04	0,25	0,8	28,63	71,46	P	0,53	P	0,21	polymorphism	0,57	0,02	.	.	.	.	.	.	COSM5651997	.	.	.	.	.	.	.	.
chrM	7941	7941	A	C	MI.5949	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	356	119	N	T	aAc/aCc	6,06	1	0	probably_damaging	1	neutral	0,43	neutral	1,92	neutral	-1,33	neutral	-2,11	low_impact	1,1	neutral	0,69	neutral	0,63	deleterious	3,45	23	0,56	0,6	neutral	0,17	neutral	0,29	disease	0,55	neutral	0,38	2	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,69	low_impact	-3,52	medium_impact	0,14	medium_impact	-0,07	0,34	0,8	28,63	71,46	P	0,54	P	0,36	disease_causing	0,71	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8806	8806	C	A	MI.595	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	280	94	P	T	Cca/Aca	-8,43	0	0	probably_damaging	1	neutral	0,23	neutral	3,63	neutral	-2,55	deleterious	-7,21	medium_impact	2,44	neutral	0,74	damaging	0,17	deleterious	3,67	23,2	0,28	0,65	disease	0,74	disease	0,55	neutral	0,49	neutral	0,44	1	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	-0,01	medium_impact	0,99	0,78	0,9	49,56	8,53	N	0,28	N	0,93	polymorphism	0,75	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7941	7941	A	T	MI.5950	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	356	119	N	I	aAc/aTc	6,06	1	0	probably_damaging	1	neutral	0,29	neutral	1,89	neutral	-2,99	deleterious	-4,13	low_impact	1,23	neutral	0,73	neutral	0,66	deleterious	4,02	23,6	0,29	0,45	neutral	0,47	disease	0,53	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,15	neutral	-2	deleterious	0,77	low_impact	-3,52	medium_impact	-0,01	medium_impact	0,05	0,35	0,8	28,63	71,46	P	0,54	P	0,88	disease_causing	0,88	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7942	7942	C	G	MI.5951	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	357	119	N	K	aaC/aaG	8,59	1	0	probably_damaging	1	neutral	0,31	neutral	1,95	neutral	-0,66	neutral	-2,1	medium_impact	2,04	neutral	0,69	neutral	0,53	deleterious	4,06	23,7	0,78	0,8	neutral	0,13	neutral	0,44	disease	0,72	neutral	0,44	1	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,7	low_impact	-3,52	medium_impact	0,01	medium_impact	0,81	0,57	0,8	28,63	71,46	P	0,56	P	0,65	disease_causing	0,91	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7942	7942	C	A	MI.5952	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	357	119	N	K	aaC/aaA	8,59	1	0	probably_damaging	1	neutral	0,31	neutral	1,95	neutral	-0,66	neutral	-2,1	medium_impact	2,04	neutral	0,69	neutral	0,53	deleterious	4,48	24,2	0,78	0,8	neutral	0,13	neutral	0,44	disease	0,72	neutral	0,44	1	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,7	low_impact	-3,52	medium_impact	0,01	medium_impact	0,81	0,57	0,8	28,63	71,46	P	0,57	P	0,65	disease_causing	0,91	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7943	7943	T	C	MI.5953	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	358	120	S	P	Tcc/Ccc	0,06	0,96	0	probably_damaging	1	neutral	0,2	neutral	1,41	deleterious	-4,48	deleterious	-4,83	high_impact	4,59	damaging	0,35	neutral	0,4	deleterious	4,12	23,8	0,27	0,45	disease	0,7	disease	0,85	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	-0,13	high_impact	3,2	0,66	0,8	69,16	19,57	P	0,75	P	0,99	disease_causing	0,91	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7943	7943	T	A	MI.5954	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	358	120	S	T	Tcc/Acc	0,06	0,96	0	probably_damaging	0,99	neutral	0,38	neutral	1,49	neutral	-2,77	deleterious	-2,88	high_impact	3,62	damaging	0,38	neutral	0,4	deleterious	4,08	23,7	0,36	0,5	neutral	0,49	disease	0,71	disease	0,66	disease	0,54	1	deleterious	0,99	neutral	0,2	deleterious	2	deleterious	0,76	low_impact	-2,58	medium_impact	0,09	high_impact	2,29	0,8	0,85	69,16	19,57	P	0,67	P	0,53	disease_causing	0,62	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7943	7943	T	G	MI.5955	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	358	120	S	A	Tcc/Gcc	0,06	0,96	0	probably_damaging	0,99	neutral	0,49	neutral	1,59	neutral	-1,76	deleterious	-2,73	medium_impact	2,9	damaging	0,53	neutral	0,73	deleterious	2,76	21,1	0,41	0,5	neutral	0,39	disease	0,54	disease	0,51	neutral	0,16	7	deleterious	0,99	neutral	0,25	deleterious	1	deleterious	0,75	low_impact	-2,58	medium_impact	0,2	medium_impact	1,61	0,76	0,85	69,16	19,57	N	0,48	N	0,36	polymorphism	0,67	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7944	7944	C	A	MI.5956	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	359	120	S	Y	tCc/tAc	5,6	1	0	probably_damaging	1	neutral	1	neutral	1,39	deleterious	-5,6	deleterious	-5,8	high_impact	4,25	damaging	0,35	neutral	0,33	deleterious	4,19	23,8	0,24	0,45	disease	0,82	disease	0,86	disease	0,78	disease	0,69	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,86	low_impact	-3,52	high_impact	1,86	high_impact	2,88	0,74	0,85	69,16	19,57	P	0,73	P	1	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7944	7944	C	T	MI.5957	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	359	120	S	F	tCc/tTc	5,6	1	0	probably_damaging	1	neutral	0,7	neutral	1,39	deleterious	-5,4	deleterious	-5,8	high_impact	4,25	damaging	0,33	neutral	0,32	deleterious	4,36	24,1	0,21	0,45	disease	0,81	disease	0,88	disease	0,78	disease	0,7	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	0,41	high_impact	2,88	0,43	0,8	69,16	19,57	P	0,76	P	0,99	disease_causing	1	0,25	.	.	.	.	.	.	COSM1331630	.	.	.	.	.	.	.	.
chrM	7944	7944	C	G	MI.5958	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	359	120	S	C	tCc/tGc	5,6	1	0	probably_damaging	1	neutral	0,17	neutral	1,4	deleterious	-5,17	deleterious	-4,79	medium_impact	3,27	damaging	0,37	neutral	0,37	deleterious	3,69	23,3	0,27	0,45	neutral	0,47	disease	0,82	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,77	low_impact	-3,52	medium_impact	-0,18	medium_impact	1,96	0,65	0,8	69,16	19,57	P	0,72	P	0,91	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7946	7946	T	A	MI.5959	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	361	121	Y	N	Tac/Aac	-11,24	0	0	probably_damaging	1	neutral	0,11	neutral	1,36	deleterious	-4,98	deleterious	-8,88	medium_impact	2,44	damaging	0,17	damaging	0,02	deleterious	4,13	23,8	0,34	0,5	neutral	0,42	disease	0,87	disease	0,76	disease	0,68	4	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,81	low_impact	-3,52	medium_impact	-0,3	medium_impact	1,18	0,26	0,8	68,28	19,64	P	0,6	P	0,99	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8806	8806	C	T	MI.596	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	280	94	P	S	Cca/Tca	-8,43	0	0	probably_damaging	1	neutral	0,43	neutral	3,66	neutral	-2,17	deleterious	-7,2	low_impact	1,82	neutral	0,73	damaging	0,19	deleterious	3,87	23,5	0,42	0,65	disease	0,59	neutral	0,35	neutral	0,47	disease	0,57	1	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,22	medium_impact	0,46	0,33	0,9	49,56	8,53	N	0,26	N	0,82	polymorphism	0,74	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7946	7946	T	C	MI.5960	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	361	121	Y	H	Tac/Cac	-11,24	0	0	probably_damaging	1	neutral	0,15	neutral	1,38	deleterious	-4,38	deleterious	-4,93	high_impact	3,84	damaging	0,12	damaging	0,02	deleterious	3,67	23,3	0,52	0,6	disease	0,63	disease	0,84	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	-0,21	high_impact	2,5	0,36	0,8	68,28	19,64	P	0,68	P	0,94	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7946	7946	T	G	MI.5961	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	361	121	Y	D	Tac/Gac	-11,24	0	0	probably_damaging	1	neutral	0,18	neutral	1,35	deleterious	-5,65	deleterious	-9,86	high_impact	4,38	damaging	0,2	damaging	0,02	deleterious	4,08	23,7	0,22	0,45	neutral	0,47	disease	0,88	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,52	medium_impact	-0,16	high_impact	3	0,32	0,8	68,28	19,64	P	0,52	P	0,99	polymorphism	0,99	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7947	7947	A	C	MI.5962	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	362	121	Y	S	tAc/tCc	5,83	1	0	probably_damaging	1	neutral	0,29	neutral	1,38	deleterious	-4,42	deleterious	-8,87	high_impact	3,58	damaging	0,13	damaging	0,02	deleterious	3,84	23,4	0,27	0,45	neutral	0,44	disease	0,85	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	-0,01	high_impact	2,25	0,23	0,8	68,28	19,64	P	0,82	P	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7947	7947	A	T	MI.5963	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	362	121	Y	F	tAc/tTc	5,83	1	0	probably_damaging	0,99	neutral	0,4	neutral	1,55	neutral	-1,85	deleterious	-3,94	low_impact	1,88	damaging	0,16	damaging	0,03	deleterious	3,63	23,2	0,4	0,5	disease	0,61	disease	0,76	disease	0,56	neutral	0,28	4	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,82	low_impact	-2,58	medium_impact	0,11	medium_impact	0,66	0,36	0,8	68,28	19,64	P	0,87	P	0,87	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7947	7947	A	G	MI.5964	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	362	121	Y	C	tAc/tGc	5,83	1	0	probably_damaging	1	neutral	0,05	neutral	1,35	deleterious	-6,12	deleterious	-8,88	high_impact	4,38	damaging	0,14	damaging	0,02	deleterious	3,67	23,3	0,37	0,5	disease	0,81	disease	0,87	disease	0,81	disease	0,69	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,5	high_impact	3	0,15	0,8	68,28	19,64	P	0,83	P	0,96	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7949	7949	A	G	MI.5965	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	364	122	M	V	Ata/Gta	-5,7	0	0	probably_damaging	0,94	neutral	0,45	neutral	1,83	neutral	-0,97	deleterious	-3,72	medium_impact	3,34	damaging	0,14	damaging	0,03	deleterious	2,72	20,9	0,49	0,55	neutral	0,23	disease	0,84	disease	0,78	disease	0,69	4	neutral	0,94	neutral	0,26	deleterious	1	deleterious	0,74	low_impact	-1,83	medium_impact	0,16	high_impact	2,03	0,51	0,8	70,93	16,47	P	0,71	P	0,89	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7949	7949	A	T	MI.5966	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	364	122	M	L	Ata/Tta	-5,7	0	0	probably_damaging	0,91	neutral	0,61	neutral	1,9	neutral	-0,54	deleterious	-2,81	medium_impact	2,17	damaging	0,17	damaging	0,05	deleterious	3,27	22,8	0,35	0,5	neutral	0,25	disease	0,82	disease	0,68	disease	0,53	1	neutral	0,9	neutral	0,35	deleterious	1	deleterious	0,67	low_impact	-1,66	medium_impact	0,31	medium_impact	0,93	0,54	0,8	70,93	16,47	P	0,72	P	0,7	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7949	7949	A	C	MI.5967	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	364	122	M	L	Ata/Cta	-5,7	0	0	probably_damaging	0,91	neutral	0,61	neutral	1,9	neutral	-0,54	deleterious	-2,81	medium_impact	2,17	damaging	0,17	damaging	0,05	deleterious	3,24	22,8	0,35	0,5	neutral	0,25	disease	0,82	disease	0,68	disease	0,53	1	neutral	0,9	neutral	0,35	deleterious	1	deleterious	0,67	low_impact	-1,66	medium_impact	0,31	medium_impact	0,93	0,54	0,8	70,93	16,47	P	0,72	P	0,7	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7950	7950	T	C	MI.5968	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	365	122	M	T	aTa/aCa	6,75	1	0	probably_damaging	0,99	neutral	0,35	neutral	1,71	neutral	-2,48	deleterious	-5,76	high_impact	3,63	damaging	0,14	damaging	0,02	deleterious	3,07	22,4	0,39	0,5	neutral	0,21	disease	0,88	disease	0,78	disease	0,68	4	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,81	low_impact	-2,58	medium_impact	0,06	high_impact	2,3	0,4	0,8	70,93	16,47	P	0,82	P	0,92	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7950	7950	T	A	MI.5969	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	365	122	M	K	aTa/aAa	6,75	1	0	probably_damaging	0,98	neutral	0,27	neutral	1,68	deleterious	-3,44	deleterious	-5,84	high_impact	4,09	damaging	0,15	damaging	0,03	deleterious	4,09	23,7	0,23	0,45	neutral	0,22	disease	0,9	disease	0,83	disease	0,71	4	deleterious	0,98	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-2,3	medium_impact	-0,03	high_impact	2,73	0,36	0,8	70,93	16,47	P	0,85	P	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8807	8807	C	A	MI.597	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	281	94	P	Q	cCa/cAa	5,45	0,99	0	probably_damaging	1	deleterious	0,01	neutral	3,59	deleterious	-3,78	deleterious	-7,24	medium_impact	3,19	neutral	0,7	damaging	0,13	deleterious	4,1	23,7	0,21	0,65	disease	0,91	disease	0,75	disease	0,74	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,82	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,64	0,74	0,9	49,56	8,53	N	0,43	N	0,82	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7951	7951	A	C	MI.5970	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	366	122	M	I	atA/atC	7,44	1	0	probably_damaging	0,96	neutral	0,42	neutral	1,84	neutral	-0,92	deleterious	-3,68	medium_impact	2,1	damaging	0,26	damaging	0,28	deleterious	3,46	23	0,48	0,55	neutral	0,26	disease	0,81	disease	0,71	disease	0,56	1	neutral	0,96	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-2,01	medium_impact	0,13	medium_impact	0,86	0,54	0,8	70,93	16,47	P	0,91	P	0,78	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7951	7951	A	T	MI.5971	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	366	122	M	I	atA/atT	7,44	1	0	probably_damaging	0,96	neutral	0,42	neutral	1,84	neutral	-0,92	deleterious	-3,68	medium_impact	2,1	damaging	0,26	damaging	0,28	deleterious	3,52	23,1	0,48	0,55	neutral	0,26	disease	0,81	disease	0,71	disease	0,56	1	neutral	0,96	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-2,01	medium_impact	0,13	medium_impact	0,86	0,54	0,8	70,93	16,47	P	0,91	P	0,78	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7952	7952	C	T	MI.5972	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	367	123	L	F	Ctt/Ttt	0,06	0	0	possibly_damaging	0,7	neutral	0,24	neutral	1,84	neutral	-2,13	neutral	-2,03	low_impact	1,9	neutral	0,73	neutral	0,59	deleterious	3,91	23,5	0,37	0,5	neutral	0,36	neutral	0,48	disease	0,66	disease	0,59	2	neutral	0,81	neutral	0,27	neutral	-3	deleterious	0,61	low_impact	-1,06	medium_impact	-0,07	medium_impact	0,68	0,56	0,8	29,96	72,1	N	0,37	N	0,39	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7952	7952	C	G	MI.5973	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	367	123	L	V	Ctt/Gtt	0,06	0	0	possibly_damaging	0,45	neutral	0,43	neutral	2,01	neutral	0,04	neutral	0,99	neutral_impact	-0,12	neutral	0,78	neutral	0,92	neutral	1,33	12,43	0,39	0,5	neutral	0,14	neutral	0,22	neutral	0,34	neutral	0,37	3	neutral	0,53	deleterious	0,49	neutral	-3	neutral	0,33	medium_impact	-0,64	medium_impact	0,14	low_impact	-1,22	0,5	0,8	29,96	72,1	N	0,31	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7952	7952	C	A	MI.5974	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	367	123	L	I	Ctt/Att	0,06	0	0	possibly_damaging	0,45	neutral	0,37	neutral	2,04	neutral	0,27	neutral	1,18	neutral_impact	-1,17	neutral	0,75	neutral	0,98	neutral	1,13	11,37	0,37	0,5	neutral	0,12	neutral	0,03	neutral	0,24	neutral	0,19	6	neutral	0,59	neutral	0,46	neutral	-3	neutral	0,32	medium_impact	-0,64	medium_impact	0,08	low_impact	-2,2	0,59	0,8	29,96	72,1	N	0,43	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7953	7953	T	A	MI.5975	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	368	123	L	H	cTt/cAt	0,29	0	0	probably_damaging	0,97	neutral	0,26	neutral	1,81	deleterious	-3,23	deleterious	-4,29	medium_impact	2,6	neutral	0,71	neutral	0,5	deleterious	4,3	24	0,29	0,45	disease	0,53	disease	0,57	disease	0,68	disease	0,71	4	neutral	0,97	neutral	0,15	deleterious	1	deleterious	0,72	low_impact	-2,13	medium_impact	-0,05	medium_impact	1,33	0,57	0,8	29,96	72,1	N	0,33	N	0,55	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7953	7953	T	C	MI.5976	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	368	123	L	P	cTt/cCt	0,29	0	0	probably_damaging	0,95	neutral	0,34	neutral	1,81	deleterious	-3,31	deleterious	-3,91	medium_impact	2,05	neutral	0,8	neutral	0,4	deleterious	3,99	23,6	0,21	0,45	neutral	0,35	disease	0,81	disease	0,65	disease	0,76	5	neutral	0,96	neutral	0,2	deleterious	1	deleterious	0,73	low_impact	-1,91	medium_impact	0,05	medium_impact	0,82	0,56	0,8	29,96	72,1	N	0,25	N	0,79	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7953	7953	T	G	MI.5977	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	368	123	L	R	cTt/cGt	0,29	0	0	probably_damaging	0,91	neutral	0,57	neutral	1,83	neutral	-2,38	deleterious	-4,01	low_impact	1,9	neutral	0,69	neutral	0,45	deleterious	4,26	23,9	0,32	0,5	neutral	0,25	disease	0,83	disease	0,71	disease	0,75	5	neutral	0,89	neutral	0,33	neutral	-2	deleterious	0,7	low_impact	-1,66	medium_impact	0,27	medium_impact	0,68	0,65	0,8	29,96	72,1	N	0,24	N	0,64	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7955	7955	C	G	MI.5978	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	370	124	P	A	Ccc/Gcc	-5,24	0	0	probably_damaging	0,99	neutral	0,49	neutral	1,86	neutral	-0,96	deleterious	-6,86	medium_impact	2,31	damaging	0,44	damaging	0,12	deleterious	3,16	22,6	0,28	0,45	neutral	0,46	disease	0,62	disease	0,59	disease	0,56	1	deleterious	0,99	neutral	0,25	deleterious	1	deleterious	0,74	low_impact	-2,58	medium_impact	0,2	medium_impact	1,06	0,51	0,8	68,72	18,75	N	0,33	N	0,9	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7955	7955	C	A	MI.5979	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	370	124	P	T	Ccc/Acc	-5,24	0	0	probably_damaging	1	neutral	0,39	neutral	1,82	neutral	-0,76	deleterious	-6,77	medium_impact	2,22	damaging	0,36	damaging	0,04	deleterious	3,77	23,4	0,3	0,45	neutral	0,44	disease	0,75	neutral	0,45	disease	0,52	0	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,76	low_impact	-3,52	medium_impact	0,1	medium_impact	0,98	0,37	0,8	68,72	18,75	N	0,37	N	0,96	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8807	8807	C	G	MI.598	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	281	94	P	R	cCa/cGa	5,45	0,99	0	probably_damaging	1	deleterious	0,01	neutral	3,6	deleterious	-3,79	deleterious	-8,15	high_impact	4,09	neutral	0,69	damaging	0,13	deleterious	3,48	23,1	0,23	0,65	disease	0,91	disease	0,78	disease	0,79	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,6	medium_impact	-0,84	high_impact	2,41	0,74	0,9	49,56	8,53	P	0,51	P	0,65	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7955	7955	C	T	MI.5980	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	370	124	P	S	Ccc/Tcc	-5,24	0	0	probably_damaging	1	neutral	0,4	neutral	1,87	neutral	-1,03	deleterious	-6,69	low_impact	1,82	damaging	0,38	damaging	0,06	deleterious	3,96	23,6	0,32	0,5	neutral	0,25	disease	0,71	neutral	0,31	neutral	0,39	2	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,73	low_impact	-3,52	medium_impact	0,11	medium_impact	0,6	0,2	0,8	68,72	18,75	N	0,36	N	0,94	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7956	7956	C	G	MI.5981	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	371	124	P	R	cCc/cGc	4,44	0,99	0	probably_damaging	1	neutral	0,33	neutral	1,81	neutral	-1,35	deleterious	-7,55	medium_impact	3,3	damaging	0,24	damaging	0,03	deleterious	3,72	23,3	0,29	0,45	disease	0,68	disease	0,89	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,84	low_impact	-3,52	medium_impact	0,04	medium_impact	1,99	0,38	0,8	68,72	18,75	P	0,79	P	0,85	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7956	7956	C	A	MI.5982	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	371	124	P	H	cCc/cAc	4,44	0,99	0	probably_damaging	1	neutral	0,52	neutral	1,78	neutral	-2,63	deleterious	-7,58	medium_impact	3,15	damaging	0,4	damaging	0,05	deleterious	4,09	23,7	0,29	0,45	disease	0,79	disease	0,84	disease	0,55	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,83	low_impact	-3,52	medium_impact	0,22	medium_impact	1,85	0,4	0,8	68,72	18,75	P	0,57	P	0,79	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7956	7956	C	T	MI.5983	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	371	124	P	L	cCc/cTc	4,44	0,99	0	probably_damaging	1	neutral	0,64	neutral	1,8	neutral	-2,45	deleterious	-8,62	medium_impact	2,25	damaging	0,36	damaging	0,03	deleterious	4,47	24,2	0,35	0,5	disease	0,72	disease	0,86	disease	0,55	disease	0,68	4	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,82	low_impact	-3,52	medium_impact	0,34	medium_impact	1	0,7	0,85	68,72	18,75	P	0,58	P	0,92	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7958	7958	C	T	MI.5984	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	373	125	P	S	Cca/Tca	-8,47	0	0	benign	0,07	neutral	0,76	neutral	2,09	neutral	-0,7	neutral	1,63	neutral_impact	-1,34	neutral	0,82	neutral	0,82	neutral	0,99	10,6	0,61	0,65	neutral	0,23	neutral	0,13	neutral	0,15	neutral	0,3	4	neutral	0,15	deleterious	0,85	neutral	-6	neutral	0,12	medium_impact	0,33	medium_impact	0,48	low_impact	-2,36	0,31	0,8	27,31	73,7	N	0,34	N	0,41	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7958	7958	C	G	MI.5985	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	373	125	P	A	Cca/Gca	-8,47	0	0	benign	0,33	neutral	0,68	neutral	2,07	neutral	-0,75	neutral	0,75	neutral_impact	-0,06	neutral	0,77	neutral	0,86	neutral	1,46	13,09	0,43	0,55	neutral	0,26	neutral	0,14	neutral	0,31	neutral	0,3	4	neutral	0,26	deleterious	0,68	neutral	-6	neutral	0,34	medium_impact	-0,43	medium_impact	0,39	low_impact	-1,16	0,82	0,85	27,31	73,7	N	0,31	N	0,32	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7958	7958	C	A	MI.5986	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	373	125	P	T	Cca/Aca	-8,47	0	0	possibly_damaging	0,57	neutral	0,75	neutral	2,09	neutral	-0,68	neutral	4,93	neutral_impact	-2,15	neutral	0,75	neutral	0,94	deleterious	0,73	9,02	0,53	0,6	neutral	0,14	neutral	0,05	neutral	0,1	neutral	0,2	6	neutral	0,48	deleterious	0,59	neutral	-3	neutral	0,41	medium_impact	-0,84	medium_impact	0,47	low_impact	-3,12	0,73	0,85	27,31	73,7	N	0,34	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7959	7959	C	G	MI.5987	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	374	125	P	R	cCa/cGa	4,44	0,99	0	possibly_damaging	0,88	neutral	0,47	neutral	2,05	neutral	-0,88	neutral	-0,34	neutral_impact	-0,59	neutral	0,66	neutral	0,47	deleterious	3,54	23,1	0,41	0,5	neutral	0,3	disease	0,51	disease	0,55	disease	0,64	3	neutral	0,87	neutral	0,3	neutral	-3	deleterious	0,62	low_impact	-1,53	medium_impact	0,18	low_impact	-1,66	0,68	0,85	27,31	73,7	N	0,41	N	0,7	polymorphism	0,94	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7959	7959	C	T	MI.5988	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	374	125	P	L	cCa/cTa	4,44	0,99	0	possibly_damaging	0,76	neutral	0,31	neutral	2,04	neutral	-2,16	neutral	-0,14	neutral_impact	-1,23	neutral	0,72	neutral	0,6	deleterious	4,24	23,9	0,5	0,6	neutral	0,31	neutral	0,31	neutral	0,32	neutral	0,45	1	neutral	0,81	neutral	0,28	neutral	-3	deleterious	0,54	low_impact	-1,19	medium_impact	0,01	low_impact	-2,26	0,74	0,85	27,31	73,7	P	0,59	P	0,74	disease_causing	0,94	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7959	7959	C	A	MI.5989	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	374	125	P	Q	cCa/cAa	4,44	0,99	0	possibly_damaging	0,88	neutral	0,59	neutral	2,06	neutral	-0,78	neutral	-0,24	neutral_impact	-0,76	neutral	0,75	neutral	0,53	deleterious	4,05	23,7	0,4	0,5	neutral	0,27	neutral	0,13	neutral	0,21	neutral	0,3	4	neutral	0,86	neutral	0,36	neutral	-3	deleterious	0,59	low_impact	-1,53	medium_impact	0,29	low_impact	-1,82	0,64	0,8	27,31	73,7	N	0,48	N	0,66	polymorphism	0,97	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8807	8807	C	T	MI.599	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	281	94	P	L	cCa/cTa	5,45	0,99	0	probably_damaging	1	neutral	0,19	neutral	3,69	neutral	-1,73	deleterious	-9,06	medium_impact	2,4	neutral	0,66	damaging	0,14	deleterious	4,28	24	0,35	0,65	disease	0,7	disease	0,71	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	-0,06	medium_impact	0,96	0,75	0,9	49,56	8,53	N	0,45	N	0,95	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7961	7961	T	G	MI.5990	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	376	126	L	V	Tta/Gta	-4,55	0	0,01	probably_damaging	0,99	neutral	0,25	neutral	1,99	neutral	-0,54	neutral	0,02	low_impact	0,82	neutral	0,71	neutral	0,7	deleterious	2,43	18,99	0,63	0,65	neutral	0,36	neutral	0,32	neutral	0,34	neutral	0,45	1	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,66	low_impact	-2,58	medium_impact	-0,06	medium_impact	-0,34	0,71	0,85	33,48	60,65	N	0,44	N	0,18	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7961	7961	T	A	MI.5991	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	376	126	L	M	Tta/Ata	-4,55	0	0,01	probably_damaging	1	neutral	0,14	neutral	1,98	neutral	-1,52	neutral	1,11	neutral_impact	0,7	neutral	0,75	neutral	0,71	deleterious	2,61	20,3	0,48	0,55	disease	0,5	neutral	0,23	neutral	0,23	neutral	0,18	6	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,67	low_impact	-3,52	medium_impact	-0,23	medium_impact	-0,45	0,7	0,85	33,48	60,65	N	0,47	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7962	7962	T	C	MI.5992	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	377	126	L	S	tTa/tCa	-2,01	0	0	probably_damaging	1	neutral	0,78	neutral	2,16	neutral	2,97	neutral	2,04	neutral_impact	-0,63	neutral	0,81	neutral	0,96	deleterious	2,22	17,66	0,52	0,6	neutral	0,16	neutral	0,24	neutral	0,17	neutral	0,42	2	deleterious	1	neutral	0,39	neutral	-2	deleterious	0,64	low_impact	-3,52	medium_impact	0,51	low_impact	-1,7	0,73	0,85	33,48	60,65	N	0,37	N	0,06	polymorphism	1	0	.	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	7962	7962	T	G	MI.5993	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	377	126	L	W	tTa/tGa	-2,01	0	0	probably_damaging	1	neutral	0,05	neutral	1,98	neutral	-1,86	neutral	-0,65	low_impact	1,79	neutral	0,66	neutral	0,49	deleterious	3,84	23,4	0,35	0,5	disease	0,78	disease	0,55	neutral	0,41	disease	0,51	0	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,76	low_impact	-3,52	medium_impact	-0,5	medium_impact	0,57	0,68	0,85	33,48	60,65	N	0,41	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7963	7963	A	C	MI.5994	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	378	126	L	F	ttA/ttC	-0,17	0	0	probably_damaging	1	neutral	0,05	neutral	1,99	neutral	-0,82	neutral	-0,72	low_impact	1,25	neutral	0,68	neutral	0,64	deleterious	3,6	23,2	0,58	0,65	disease	0,56	neutral	0,38	neutral	0,36	disease	0,62	2	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,71	low_impact	-3,52	medium_impact	-0,5	medium_impact	0,07	0,54	0,8	33,48	60,65	N	0,46	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7963	7963	A	T	MI.5995	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	378	126	L	F	ttA/ttT	-0,17	0	0	probably_damaging	1	neutral	0,05	neutral	1,99	neutral	-0,82	neutral	-0,72	low_impact	1,25	neutral	0,68	neutral	0,64	deleterious	3,64	23,2	0,58	0,65	disease	0,56	neutral	0,38	neutral	0,36	disease	0,62	2	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,71	low_impact	-3,52	medium_impact	-0,5	medium_impact	0,07	0,54	0,8	33,48	60,65	N	0,46	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7964	7964	T	C	MI.5996	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	379	127	F	L	Ttc/Ctc	-0,4	0	0,01	probably_damaging	0,99	neutral	0,7	neutral	2,05	neutral	1,46	neutral	-1,1	neutral_impact	-0,02	neutral	0,76	neutral	0,49	deleterious	4,09	23,7	0,49	0,55	neutral	0,17	neutral	0,42	disease	0,52	neutral	0,47	1	deleterious	0,99	neutral	0,36	neutral	-2	deleterious	0,65	low_impact	-2,58	medium_impact	0,41	low_impact	-1,12	0,31	0,8	28,19	61,06	N	0,28	N	0,51	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7964	7964	T	G	MI.5997	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	379	127	F	V	Ttc/Gtc	-0,4	0	0,01	probably_damaging	0,99	neutral	0,43	neutral	2,02	neutral	0,92	neutral	-0,31	low_impact	1,3	neutral	0,7	neutral	0,61	deleterious	4,13	23,8	0,45	0,55	neutral	0,23	disease	0,54	disease	0,55	disease	0,61	2	deleterious	0,99	neutral	0,22	neutral	-2	deleterious	0,65	low_impact	-2,58	medium_impact	0,14	medium_impact	0,11	0,42	0,8	28,19	61,06	N	0,34	N	0,5	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7964	7964	T	A	MI.5998	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	379	127	F	I	Ttc/Atc	-0,4	0	0,01	probably_damaging	0,99	neutral	0,3	neutral	2,01	neutral	0,34	neutral	-0,42	low_impact	1,3	neutral	0,69	neutral	0,58	deleterious	4,43	24,2	0,46	0,55	neutral	0,16	neutral	0,43	disease	0,54	neutral	0,48	0	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,65	low_impact	-2,58	medium_impact	0	medium_impact	0,11	0,33	0,8	28,19	61,06	N	0,4	N	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7965	7965	T	G	MI.5999	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	380	127	F	C	tTc/tGc	5,13	1	0	probably_damaging	1	neutral	0,1	neutral	1,98	neutral	-1,48	neutral	-0,73	low_impact	1,3	neutral	0,66	neutral	0,45	deleterious	4,2	23,9	0,33	0,5	disease	0,56	disease	0,61	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,71	low_impact	-3,52	medium_impact	-0,32	medium_impact	0,11	0,27	0,8	28,19	61,06	P	0,51	P	0,59	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8529	8529	G	C	MI.6	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	3	1	M	I	atG/atC	7,53	1	0	possibly_damaging	0,72	deleterious	0	neutral	4,58	neutral	0,17	deleterious	-3,33	NA	NA	neutral	0,68	damaging	0,12	deleterious	4,06	23,7	0,46	0,65	disease	0,77	neutral	0,44	disease	0,64	disease	0,61	2	deleterious	1	neutral	0,14	deleterious	3	deleterious	0,68	NA	NA	NA	NA	NA	NA	0,55	0,9	50	8,74	P	0,6	P	0,94	NA	NA	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8553	8553	C	G	MI.60	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	27	9	F	L	ttC/ttG	7,53	1	0	probably_damaging	0,92	neutral	0,06	neutral	3,94	neutral	-0,84	deleterious	-5,27	medium_impact	2,34	damaging	0,57	neutral	0,59	deleterious	4,64	24,5	0,4	0,65	disease	0,6	disease	0,77	disease	0,82	disease	0,8	6	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,76	low_impact	-1,76	medium_impact	-0,38	medium_impact	0,91	0,44	0,9	49,56	8,77	P	0,59	P	0,89	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8809	8809	A	C	MI.600	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	283	95	T	P	Acc/Ccc	-13,29	0	0	probably_damaging	1	deleterious	0,01	neutral	3,28	deleterious	-4,81	deleterious	-5,53	high_impact	3,84	damaging	0,53	damaging	0,13	deleterious	4	23,6	0,21	0,65	disease	0,96	disease	0,68	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,6	medium_impact	-0,84	high_impact	2,19	0,5	0,9	50,44	8,81	N	0,31	N	0,99	disease_causing	0,98	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7965	7965	T	C	MI.6000	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	380	127	F	S	tTc/tCc	5,13	1	0	probably_damaging	1	neutral	0,95	neutral	2,08	neutral	2,11	neutral	2,26	neutral_impact	-0,61	neutral	0,68	neutral	0,71	deleterious	4,39	24,1	0,36	0,5	neutral	0,15	neutral	0,43	neutral	0,36	neutral	0,44	1	deleterious	1	deleterious	0,48	neutral	-2	deleterious	0,65	low_impact	-3,52	medium_impact	0,91	low_impact	-1,68	0,3	0,8	28,19	61,06	N	0,47	N	0,38	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7965	7965	T	A	MI.6001	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	380	127	F	Y	tTc/tAc	5,13	1	0	probably_damaging	0,99	neutral	0,51	neutral	2	neutral	-0,13	neutral	0,04	neutral_impact	0,02	neutral	0,73	neutral	0,75	deleterious	4,53	24,3	0,46	0,55	neutral	0,37	neutral	0,32	disease	0,55	neutral	0,47	1	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,67	low_impact	-2,58	medium_impact	0,21	low_impact	-1,09	0,38	0,8	28,19	61,06	P	0,56	P	0,31	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7966	7966	C	G	MI.6002	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	381	127	F	L	ttC/ttG	4,67	1	0	probably_damaging	0,99	neutral	0,7	neutral	2,05	neutral	1,46	neutral	-1,1	neutral_impact	-0,02	neutral	0,76	neutral	0,49	deleterious	4,49	24,3	0,49	0,55	neutral	0,17	neutral	0,42	disease	0,52	neutral	0,47	1	deleterious	0,99	neutral	0,36	neutral	-2	deleterious	0,65	low_impact	-2,58	medium_impact	0,41	low_impact	-1,12	0,31	0,8	28,19	61,06	N	0,44	N	0,51	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7966	7966	C	A	MI.6003	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	381	127	F	L	ttC/ttA	4,67	1	0	probably_damaging	0,99	neutral	0,7	neutral	2,05	neutral	1,46	neutral	-1,1	neutral_impact	-0,02	neutral	0,76	neutral	0,49	deleterious	4,81	24,8	0,49	0,55	neutral	0,17	neutral	0,42	disease	0,52	neutral	0,47	1	deleterious	0,99	neutral	0,36	neutral	-2	deleterious	0,65	low_impact	-2,58	medium_impact	0,41	low_impact	-1,12	0,31	0,8	28,19	61,06	N	0,44	N	0,51	polymorphism	1	0,01	rs879093898	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7967	7967	C	G	MI.6004	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	382	128	L	V	Cta/Gta	-4,32	0	0	probably_damaging	0,99	neutral	0,3	neutral	1,49	neutral	-2,37	deleterious	-2,96	medium_impact	2,81	damaging	0,34	neutral	0,33	deleterious	3,5	23,1	0,52	0,6	neutral	0,37	disease	0,51	disease	0,62	disease	0,62	2	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,71	low_impact	-2,58	medium_impact	0	medium_impact	1,53	0,37	0,8	68,72	19,83	P	0,54	P	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7967	7967	C	A	MI.6005	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	382	128	L	M	Cta/Ata	-4,32	0	0	probably_damaging	1	neutral	0,13	neutral	1,42	deleterious	-3,23	neutral	-1,97	low_impact	1,9	damaging	0,48	neutral	0,48	deleterious	3,78	23,4	0,28	0,45	disease	0,59	neutral	0,15	neutral	0,29	neutral	0,34	3	deleterious	1	neutral	0,07	neutral	-2	deleterious	0,71	low_impact	-3,52	medium_impact	-0,25	medium_impact	0,68	0,65	0,8	68,72	19,83	P	0,49	N	0,78	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7968	7968	T	G	MI.6006	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	383	128	L	R	cTa/cGa	-1,32	0	0	probably_damaging	1	neutral	0,54	neutral	1,37	deleterious	-4,66	deleterious	-5,92	medium_impact	3,26	damaging	0,28	damaging	0,26	deleterious	4,27	24	0,28	0,45	disease	0,66	disease	0,85	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,85	low_impact	-3,52	medium_impact	0,24	medium_impact	1,95	0,5	0,8	68,72	19,83	P	0,8	P	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7968	7968	T	A	MI.6007	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	383	128	L	Q	cTa/cAa	-1,32	0	0	probably_damaging	1	neutral	0,58	neutral	1,36	deleterious	-4,75	deleterious	-5,92	medium_impact	3	damaging	0,44	neutral	0,34	deleterious	4,16	23,8	0,28	0,45	disease	0,67	disease	0,7	disease	0,56	disease	0,6	2	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,79	low_impact	-3,52	medium_impact	0,28	medium_impact	1,71	0,53	0,8	68,72	19,83	N	0,4	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7968	7968	T	C	MI.6008	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	383	128	L	P	cTa/cCa	-1,32	0	0	probably_damaging	1	neutral	0,3	neutral	1,36	deleterious	-4,77	deleterious	-6,9	medium_impact	2,96	damaging	0,28	neutral	0,32	deleterious	4,01	23,6	0,24	0,45	neutral	0,32	disease	0,81	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,78	low_impact	-3,52	medium_impact	0	medium_impact	1,67	0,36	0,8	68,72	19,83	P	0,75	P	0,99	polymorphism	0,98	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7970	7970	G	C	MI.6009	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	385	129	E	Q	Gaa/Caa	-1,78	0	0	benign	0,14	neutral	0,6	neutral	1,86	neutral	-1,42	neutral	-0,31	neutral_impact	0,6	neutral	0,8	neutral	0,78	neutral	-0,35	0,52	0,59	0,65	neutral	0,24	neutral	0,16	neutral	0,24	neutral	0,29	4	neutral	0,29	deleterious	0,73	neutral	-6	neutral	0,16	medium_impact	0,01	medium_impact	0,3	medium_impact	-0,54	0,57	0,8	34,8	62,05	N	0,33	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8809	8809	A	T	MI.601	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	283	95	T	S	Acc/Tcc	-13,29	0	0	probably_damaging	0,99	neutral	0,22	neutral	3,47	neutral	-1,81	deleterious	-3,64	medium_impact	2,25	neutral	0,68	damaging	0,17	deleterious	3,86	23,4	0,31	0,65	disease	0,75	neutral	0,28	disease	0,57	disease	0,53	1	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,76	low_impact	-2,65	medium_impact	-0,02	medium_impact	0,83	0,74	0,9	50,44	8,81	N	0,31	N	0,88	disease_causing	0,8	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7970	7970	G	A	MI.6010	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	385	129	E	K	Gaa/Aaa	-1,78	0	0	benign	0	neutral	0,93	neutral	1,92	neutral	-1,01	neutral	-0,25	neutral_impact	-0,12	neutral	0,78	neutral	0,93	deleterious	0,1	3,61	0,43	0,55	neutral	0,25	neutral	0,27	neutral	0,25	neutral	0,44	1	neutral	0,05	deleterious	0,97	neutral	-6	neutral	0,13	high_impact	2,08	medium_impact	0,83	low_impact	-1,22	0,74	0,85	34,8	62,05	N	0,3	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7971	7971	A	G	MI.6011	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	386	129	E	G	gAa/gGa	0,06	0	0	benign	0,14	neutral	0,39	neutral	1,81	neutral	-2,59	neutral	-1,95	low_impact	1,31	neutral	0,76	neutral	0,64	neutral	0,96	10,41	0,49	0,55	disease	0,53	neutral	0,24	neutral	0,42	neutral	0,34	3	neutral	0,54	deleterious	0,63	neutral	-6	neutral	0,2	medium_impact	0,01	medium_impact	0,1	medium_impact	0,12	0,52	0,8	34,8	62,05	N	0,4	N	0,48	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7971	7971	A	T	MI.6012	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	386	129	E	V	gAa/gTa	0,06	0	0	benign	0,34	neutral	0,32	neutral	1,81	neutral	-2,86	neutral	-1,03	low_impact	1,55	neutral	0,77	neutral	0,7	neutral	1,1	11,2	0,42	0,55	neutral	0,38	neutral	0,41	neutral	0,39	neutral	0,46	1	neutral	0,62	deleterious	0,49	neutral	-6	neutral	0,31	medium_impact	-0,45	medium_impact	0,02	medium_impact	0,35	0,65	0,8	34,8	62,05	N	0,41	N	0,59	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7971	7971	A	C	MI.6013	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	386	129	E	A	gAa/gCa	0,06	0	0	benign	0,14	neutral	0,77	neutral	1,89	neutral	-1,17	neutral	-0,2	neutral_impact	0,38	neutral	0,78	neutral	0,85	neutral	-0,37	0,46	0,45	0,55	neutral	0,35	neutral	0,23	neutral	0,36	neutral	0,43	1	neutral	0,12	deleterious	0,82	neutral	-6	neutral	0,19	medium_impact	0,01	medium_impact	0,5	medium_impact	-0,75	0,55	0,8	34,8	62,05	N	0,27	N	0,22	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7972	7972	A	C	MI.6014	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	387	129	E	D	gaA/gaC	0,29	0	0	benign	0,09	neutral	0,63	neutral	1,86	neutral	-0,39	neutral	-0,96	neutral_impact	0,44	neutral	0,77	neutral	0,75	deleterious	0,15	4,09	0,6	0,65	neutral	0,41	neutral	0,22	neutral	0,19	neutral	0,41	2	neutral	0,27	deleterious	0,77	neutral	-6	neutral	0,16	medium_impact	0,22	medium_impact	0,33	medium_impact	-0,69	0,78	0,85	34,8	62,05	N	0,38	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7972	7972	A	T	MI.6015	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	387	129	E	D	gaA/gaT	0,29	0	0	benign	0,09	neutral	0,63	neutral	1,86	neutral	-0,39	neutral	-0,96	neutral_impact	0,44	neutral	0,77	neutral	0,75	deleterious	0,24	5,14	0,6	0,65	neutral	0,41	neutral	0,22	neutral	0,19	neutral	0,41	2	neutral	0,27	deleterious	0,77	neutral	-6	neutral	0,16	medium_impact	0,22	medium_impact	0,33	medium_impact	-0,69	0,78	0,85	34,8	62,05	N	0,38	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7973	7973	C	T	MI.6016	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	388	130	P	S	Cca/Tca	-6,86	0	0	probably_damaging	1	neutral	0,77	neutral	2,04	neutral	-0,7	deleterious	-4,45	low_impact	1,16	neutral	0,62	neutral	0,49	deleterious	2,71	20,8	0,57	0,65	neutral	0,27	neutral	0,18	neutral	0,18	neutral	0,3	4	deleterious	1	neutral	0,39	neutral	-2	deleterious	0,65	low_impact	-3,52	medium_impact	0,5	medium_impact	-0,02	0,3	0,8	67,84	18,83	N	0,33	N	0,94	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7973	7973	C	G	MI.6017	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	388	130	P	A	Cca/Gca	-6,86	0	0	probably_damaging	0,99	neutral	0,81	neutral	2,03	neutral	-0,42	deleterious	-4,93	low_impact	1,64	damaging	0,59	neutral	0,33	deleterious	2,04	16,47	0,48	0,55	neutral	0,25	neutral	0,2	neutral	0,33	neutral	0,37	3	deleterious	0,99	neutral	0,41	neutral	-2	deleterious	0,65	low_impact	-2,58	medium_impact	0,55	medium_impact	0,43	0,74	0,85	67,84	18,83	N	0,24	N	0,9	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7973	7973	C	A	MI.6018	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	388	130	P	T	Cca/Aca	-6,86	0	0	probably_damaging	1	neutral	0,62	neutral	2,02	neutral	-1,22	deleterious	-4,83	low_impact	1,34	damaging	0,57	damaging	0,2	deleterious	2,81	21,4	0,49	0,55	neutral	0,16	neutral	0,17	neutral	0,32	neutral	0,28	4	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,63	low_impact	-3,52	medium_impact	0,32	medium_impact	0,15	0,68	0,85	67,84	18,83	N	0,23	N	0,96	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7974	7974	C	T	MI.6019	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	389	130	P	L	cCa/cTa	0,98	0	0	probably_damaging	1	neutral	0,42	neutral	2,02	neutral	-1,21	deleterious	-6,66	low_impact	0,94	damaging	0,58	neutral	0,53	deleterious	3,17	22,7	0,49	0,55	neutral	0,16	neutral	0,32	neutral	0,35	neutral	0,43	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,65	low_impact	-3,52	medium_impact	0,13	medium_impact	-0,22	0,88	0,9	67,84	18,83	N	0,35	N	0,92	disease_causing	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8809	8809	A	G	MI.602	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	283	95	T	A	Acc/Gcc	-13,29	0	0	probably_damaging	0,99	neutral	0,06	neutral	3,31	deleterious	-3,67	deleterious	-4,55	high_impact	3,73	neutral	0,69	damaging	0,15	deleterious	4,01	23,6	0,38	0,65	disease	0,85	neutral	0,4	disease	0,77	disease	0,68	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,79	low_impact	-2,65	medium_impact	-0,38	high_impact	2,1	0,62	0,9	50,44	8,81	N	0,38	N	0,63	disease_causing	0,92	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7974	7974	C	G	MI.6020	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	389	130	P	R	cCa/cGa	0,98	0	0	probably_damaging	1	neutral	0,56	neutral	2,01	neutral	-1,25	deleterious	-5,59	low_impact	1,84	damaging	0,44	damaging	0,11	deleterious	3,63	23,2	0,49	0,55	neutral	0,33	disease	0,51	neutral	0,45	neutral	0,49	0	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,7	low_impact	-3,52	medium_impact	0,26	medium_impact	0,62	0,68	0,85	67,84	18,83	N	0,33	N	0,85	polymorphism	0,77	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7974	7974	C	A	MI.6021	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	389	130	P	Q	cCa/cAa	0,98	0	0	probably_damaging	1	neutral	0,62	neutral	2,02	neutral	-1,18	deleterious	-4,85	low_impact	1,76	neutral	0,65	neutral	0,41	deleterious	3,11	22,5	0,47	0,55	neutral	0,31	neutral	0,25	neutral	0,28	neutral	0,44	1	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,67	low_impact	-3,52	medium_impact	0,32	medium_impact	0,55	0,49	0,8	67,84	18,83	N	0,29	N	0,88	polymorphism	0,86	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7976	7976	G	A	MI.6022	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	391	131	G	S	Ggc/Agc	-5,24	0	0	probably_damaging	1	neutral	0,93	neutral	1,88	neutral	-1,36	deleterious	-5,88	medium_impact	2,06	damaging	0,57	damaging	0,22	deleterious	4,23	23,9	0,64	0,7	neutral	0,39	neutral	0,47	neutral	0,33	neutral	0,39	2	deleterious	1	neutral	0,47	deleterious	1	deleterious	0,71	low_impact	-3,52	medium_impact	0,83	medium_impact	0,83	0,88	0,9	67,84	19,7	N	0,23	N	0,98	disease_causing	0,88	0,05	rs377368526	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7976	7976	G	T	MI.6023	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	391	131	G	C	Ggc/Tgc	-5,24	0	0	probably_damaging	1	neutral	0,2	neutral	1,76	deleterious	-5,67	deleterious	-8,81	high_impact	4,08	damaging	0,46	damaging	0,18	deleterious	4,27	23,9	0,24	0,45	disease	0,77	disease	0,79	disease	0,59	disease	0,7	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,8	low_impact	-3,52	medium_impact	-0,13	high_impact	2,72	0,41	0,8	67,84	19,7	N	0,34	N	0,99	disease_causing	0,97	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7976	7976	G	C	MI.6024	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	391	131	G	R	Ggc/Cgc	-5,24	0	0	probably_damaging	1	neutral	0,7	neutral	1,84	neutral	-2,21	deleterious	-7,84	medium_impact	3,11	damaging	0,39	damaging	0,16	deleterious	4,08	23,7	0,38	0,5	neutral	0,47	disease	0,83	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	0,41	medium_impact	1,81	0,86	0,9	67,84	19,7	N	0,41	N	1	disease_causing	0,94	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7977	7977	G	T	MI.6025	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	392	131	G	V	gGc/gTc	9,05	1	0	probably_damaging	1	neutral	0,67	neutral	1,78	deleterious	-3,02	deleterious	-8,82	medium_impact	3,19	damaging	0,46	damaging	0,2	deleterious	3,86	23,5	0,39	0,5	neutral	0,43	disease	0,72	disease	0,58	disease	0,67	3	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,76	low_impact	-3,52	medium_impact	0,38	medium_impact	1,89	0,44	0,8	67,84	19,7	N	0,47	N	1	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7977	7977	G	A	MI.6026	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	392	131	G	D	gGc/gAc	9,05	1	0	probably_damaging	1	neutral	0,65	neutral	1,89	neutral	-1,89	deleterious	-6,87	medium_impact	2,21	damaging	0,53	damaging	0,17	deleterious	3,91	23,5	0,42	0,5	neutral	0,42	disease	0,67	neutral	0,49	neutral	0,23	5	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,74	low_impact	-3,52	medium_impact	0,35	medium_impact	0,97	0,41	0,8	67,84	19,7	N	0,37	N	0,99	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7977	7977	G	C	MI.6027	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	392	131	G	A	gGc/gCc	9,05	1	0	probably_damaging	1	neutral	0,99	neutral	1,83	neutral	-1,53	deleterious	-5,88	medium_impact	3,04	damaging	0,58	neutral	0,34	deleterious	3,22	22,8	0,62	0,65	neutral	0,37	disease	0,57	disease	0,56	disease	0,64	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,72	low_impact	-3,52	medium_impact	1,31	medium_impact	1,75	0,66	0,8	67,84	19,7	N	0,44	N	0,85	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7979	7979	G	T	MI.6028	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	394	132	D	Y	Gac/Tac	-11,24	0	0	probably_damaging	1	neutral	0,17	neutral	1,93	deleterious	-3,92	neutral	-0,3	low_impact	0,96	neutral	0,76	neutral	0,74	deleterious	2,97	22,1	0,33	0,5	disease	0,66	neutral	0,42	neutral	0,5	disease	0,6	2	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,72	low_impact	-3,52	medium_impact	-0,18	medium_impact	-0,21	0,19	0,8	30,84	49,86	N	0,42	N	0,82	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7979	7979	G	C	MI.6029	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	394	132	D	H	Gac/Cac	-11,24	0	0	probably_damaging	1	neutral	0,18	neutral	1,95	neutral	-2,82	neutral	1,29	low_impact	0,87	neutral	0,76	neutral	0,85	deleterious	2,05	16,53	0,41	0,5	neutral	0,47	neutral	0,3	neutral	0,34	neutral	0,42	2	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,67	low_impact	-3,52	medium_impact	-0,16	medium_impact	-0,29	0,38	0,8	30,84	49,86	N	0,43	N	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8810	8810	C	T	MI.603	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	284	95	T	I	aCc/aTc	6,84	1	0	probably_damaging	1	deleterious	0,01	neutral	3,29	deleterious	-4,35	deleterious	-5,5	high_impact	3,98	neutral	0,66	damaging	0,14	deleterious	3,89	23,5	0,31	0,65	disease	0,97	disease	0,71	disease	0,79	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,6	medium_impact	-0,84	high_impact	2,31	0,74	0,9	50,44	8,81	P	0,52	P	0,97	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7979	7979	G	A	MI.6030	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	394	132	D	N	Gac/Aac	-11,24	0	0	probably_damaging	1	neutral	0,5	neutral	2,01	neutral	-1,63	neutral	-0,04	neutral_impact	0,42	neutral	0,74	neutral	0,85	deleterious	3,11	22,5	0,68	0,7	neutral	0,32	neutral	0,13	neutral	0,2	neutral	0,27	5	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,64	low_impact	-3,52	medium_impact	0,21	medium_impact	-0,71	0,57	0,8	30,84	49,86	N	0,42	N	0,39	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7980	7980	A	G	MI.6031	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	395	132	D	G	gAc/gGc	0,52	0	0	probably_damaging	1	neutral	0,42	neutral	1,98	neutral	-2,45	neutral	-1,72	neutral_impact	0,12	neutral	0,77	neutral	0,79	deleterious	3,32	22,9	0,35	0,5	neutral	0,43	neutral	0,19	neutral	0,32	neutral	0,36	3	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,66	low_impact	-3,52	medium_impact	0,13	medium_impact	-0,99	0,38	0,8	30,84	49,86	N	0,33	N	0,79	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7980	7980	A	T	MI.6032	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	395	132	D	V	gAc/gTc	0,52	0	0	probably_damaging	1	neutral	0,34	neutral	1,95	neutral	-2,85	neutral	-2,05	low_impact	1,66	neutral	0,71	neutral	0,63	deleterious	4,39	24,1	0,34	0,5	disease	0,52	neutral	0,41	neutral	0,43	neutral	0,33	3	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,69	low_impact	-3,52	medium_impact	0,05	medium_impact	0,45	0,24	0,8	30,84	49,86	N	0,39	N	0,77	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7980	7980	A	C	MI.6033	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	395	132	D	A	gAc/gCc	0,52	0	0	probably_damaging	1	neutral	0,75	neutral	2,02	neutral	-1,49	neutral	-1,28	low_impact	1,11	neutral	0,79	neutral	0,69	deleterious	3,14	22,6	0,35	0,5	neutral	0,21	neutral	0,35	neutral	0,41	neutral	0,42	2	deleterious	1	neutral	0,38	neutral	-2	deleterious	0,65	low_impact	-3,52	medium_impact	0,47	medium_impact	-0,07	0,32	0,8	30,84	49,86	N	0,24	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7981	7981	C	G	MI.6034	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	396	132	D	E	gaC/gaG	2,14	0	0	probably_damaging	1	neutral	1	neutral	2,1	neutral	-0,56	neutral	1,34	neutral_impact	-0,46	neutral	0,76	neutral	0,95	deleterious	2,16	17,25	0,56	0,6	neutral	0,2	neutral	0,19	neutral	0,18	neutral	0,37	3	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,62	low_impact	-3,52	high_impact	1,86	low_impact	-1,54	0,41	0,8	30,84	49,86	N	0,3	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7981	7981	C	A	MI.6035	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	396	132	D	E	gaC/gaA	2,14	0	0	probably_damaging	1	neutral	1	neutral	2,1	neutral	-0,56	neutral	1,34	neutral_impact	-0,46	neutral	0,76	neutral	0,95	deleterious	2,51	19,5	0,56	0,6	neutral	0,2	neutral	0,19	neutral	0,18	neutral	0,37	3	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,62	low_impact	-3,52	high_impact	1,86	low_impact	-1,54	0,41	0,8	30,84	49,86	N	0,3	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7982	7982	C	A	MI.6036	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	397	133	L	M	Ctg/Atg	-2,01	0	0	probably_damaging	1	neutral	0,23	neutral	1,87	neutral	-2,04	neutral	-0,28	low_impact	1,48	neutral	0,74	neutral	0,56	deleterious	3,92	23,5	0,38	0,5	disease	0,65	neutral	0,45	neutral	0,37	disease	0,59	2	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,77	low_impact	-3,52	medium_impact	-0,09	medium_impact	0,28	0,77	0,85	68,28	16,14	N	0,43	N	0,78	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7982	7982	C	G	MI.6037	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	397	133	L	V	Ctg/Gtg	-2,01	0	0	probably_damaging	0,99	neutral	0,51	neutral	1,93	neutral	-0,73	neutral	-1,06	low_impact	1,38	neutral	0,71	neutral	0,52	deleterious	3,5	23,1	0,36	0,5	disease	0,55	disease	0,56	disease	0,54	disease	0,62	2	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,77	low_impact	-2,58	medium_impact	0,21	medium_impact	0,19	0,41	0,8	68,28	16,14	N	0,27	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7983	7983	T	G	MI.6038	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	398	133	L	R	cTg/cGg	0,06	0,02	0	probably_damaging	1	neutral	0,39	neutral	1,87	neutral	-1,8	deleterious	-3,08	low_impact	1,58	neutral	0,63	neutral	0,4	deleterious	4,32	24	0,24	0,45	neutral	0,38	disease	0,88	disease	0,68	disease	0,77	5	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,82	low_impact	-3,52	medium_impact	0,1	medium_impact	0,38	0,56	0,8	68,28	16,14	N	0,32	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7983	7983	T	C	MI.6039	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	398	133	L	P	cTg/cCg	0,06	0,02	0	probably_damaging	1	neutral	0,22	neutral	1,87	neutral	-1,92	deleterious	-3,01	neutral_impact	-0,14	neutral	0,71	neutral	0,42	deleterious	2,93	22	0,22	0,45	neutral	0,46	disease	0,85	neutral	0,33	neutral	0,2	6	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,1	low_impact	-1,24	0,46	0,8	68,28	16,14	N	0,32	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8810	8810	C	A	MI.604	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	284	95	T	N	aCc/aAc	6,84	1	0	probably_damaging	1	deleterious	0	neutral	3,3	deleterious	-3,87	deleterious	-4,58	high_impact	3,63	neutral	0,67	damaging	0,13	deleterious	3,74	23,3	0,26	0,65	disease	0,96	disease	0,63	disease	0,75	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,6	low_impact	-1,4	high_impact	2,01	0,72	0,9	50,44	8,81	N	0,49	N	0,9	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7983	7983	T	A	MI.6040	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	398	133	L	Q	cTg/cAg	0,06	0,02	0	probably_damaging	1	neutral	0,32	neutral	1,86	neutral	-2,21	deleterious	-2,95	low_impact	1,73	neutral	0,69	neutral	0,47	deleterious	4,31	24	0,22	0,45	neutral	0,46	disease	0,71	disease	0,55	disease	0,67	3	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,78	low_impact	-3,52	medium_impact	0,02	medium_impact	0,52	0,49	0,8	68,28	16,14	N	0,32	N	0,95	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7985	7985	C	G	MI.6041	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	400	134	R	G	Cga/Gga	-8,7	0	0	probably_damaging	1	neutral	0,37	neutral	1,51	deleterious	-3,84	deleterious	-6,93	high_impact	3,72	damaging	0,32	damaging	0,23	deleterious	4,31	24	0,26	0,45	disease	0,63	disease	0,8	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,79	low_impact	-3,52	medium_impact	0,08	high_impact	2,38	0,44	0,8	68,72	19,77	P	0,6	P	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7985	7985	C	T	MI.6042	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	400	134	R	W	Cga/Tga	-8,7	0	0	probably_damaging	1	neutral	0,18	neutral	1,47	deleterious	-6,72	deleterious	-7,92	high_impact	3,98	damaging	0,32	damaging	0,1	deleterious	5,24	25,6	0,37	0,5	disease	0,92	disease	0,89	disease	0,79	disease	0,62	2	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,16	high_impact	2,63	0,71	0,85	68,72	19,77	P	0,56	P	1	polymorphism	0,99	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7986	7986	G	T	MI.6043	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	401	134	R	L	cGa/cTa	2,83	0,97	0	probably_damaging	1	neutral	0,75	neutral	1,51	deleterious	-3,65	deleterious	-6,93	high_impact	3,83	damaging	0,28	damaging	0,28	deleterious	4,49	24,3	0,3	0,45	disease	0,57	disease	0,91	disease	0,76	disease	0,7	4	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	0,47	high_impact	2,49	0,31	0,8	68,72	19,77	P	0,86	P	1	disease_causing	1	0,08	.	.	.	.	.	pancreatic cancer cell line	.	.	.	.	.	.	.	.	.
chrM	7986	7986	G	A	MI.6044	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	401	134	R	Q	cGa/cAa	2,83	0,97	0	probably_damaging	1	neutral	0,3	neutral	1,54	deleterious	-3,03	deleterious	-3,96	high_impact	3,72	damaging	0,31	damaging	0,14	deleterious	4,63	24,5	0,54	0,6	neutral	0,47	disease	0,85	disease	0,79	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,79	low_impact	-3,52	medium_impact	0	high_impact	2,38	0,94	0,95	68,72	19,77	P	0,82	P	1	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7986	7986	G	C	MI.6045	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	401	134	R	P	cGa/cCa	2,83	0,97	0	probably_damaging	1	neutral	0,24	neutral	1,49	deleterious	-4,58	deleterious	-6,93	high_impact	3,72	damaging	0,31	damaging	0,15	deleterious	4,37	24,1	0,16	0,45	disease	0,71	disease	0,88	disease	0,8	disease	0,72	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,07	high_impact	2,38	0,28	0,8	68,72	19,77	P	0,74	P	1	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7988	7988	C	G	MI.6046	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	403	135	L	V	Ctc/Gtc	-3,63	0	0	probably_damaging	0,99	neutral	0,51	neutral	1,56	neutral	-2,46	deleterious	-2,97	medium_impact	2,85	damaging	0,13	damaging	0,01	deleterious	3,52	23,1	0,46	0,55	neutral	0,41	disease	0,75	disease	0,55	disease	0,63	3	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,77	low_impact	-2,58	medium_impact	0,21	medium_impact	1,57	0,66	0,8	68,28	19,43	P	0,68	P	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7988	7988	C	A	MI.6047	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	403	135	L	I	Ctc/Atc	-3,63	0	0	probably_damaging	1	neutral	0,39	neutral	1,56	neutral	-2,43	neutral	-1,98	medium_impact	3,12	damaging	0,17	damaging	0,02	deleterious	4,21	23,9	0,45	0,55	neutral	0,37	disease	0,73	disease	0,66	disease	0,65	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,75	low_impact	-3,52	medium_impact	0,1	medium_impact	1,82	0,7	0,85	68,28	19,43	P	0,76	P	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7988	7988	C	T	MI.6048	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	403	135	L	F	Ctc/Ttc	-3,63	0	0	probably_damaging	1	neutral	0,7	neutral	1,5	deleterious	-3,51	deleterious	-3,96	medium_impact	2,81	damaging	0,12	damaging	0,01	deleterious	4,13	23,8	0,44	0,55	disease	0,62	disease	0,77	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,82	low_impact	-3,52	medium_impact	0,41	medium_impact	1,53	0,61	0,8	68,28	19,43	P	0,7	P	0,91	polymorphism	0,99	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7989	7989	T	C	MI.6049	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	404	135	L	P	cTc/cCc	-0,4	0	0	probably_damaging	1	neutral	0,23	neutral	1,46	deleterious	-5,1	deleterious	-6,93	medium_impact	3,23	damaging	0,14	damaging	0,01	deleterious	4,08	23,7	0,18	0,45	disease	0,71	disease	0,86	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,88	low_impact	-3,52	medium_impact	-0,09	medium_impact	1,92	0,5	0,8	68,28	19,43	P	0,71	P	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	T7989C	Rhabdomyolysis	-	+	Reported	2
chrM	8810	8810	C	G	MI.605	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	284	95	T	S	aCc/aGc	6,84	1	0	probably_damaging	0,99	neutral	0,22	neutral	3,47	neutral	-1,81	deleterious	-3,64	medium_impact	2,25	neutral	0,68	damaging	0,17	deleterious	3,46	23	0,31	0,65	disease	0,75	neutral	0,28	disease	0,57	disease	0,53	1	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,76	low_impact	-2,65	medium_impact	-0,02	medium_impact	0,83	0,74	0,9	50,44	8,81	P	0,56	P	0,88	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7989	7989	T	A	MI.6050	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	404	135	L	H	cTc/cAc	-0,4	0	0	probably_damaging	1	neutral	0,54	neutral	1,46	deleterious	-4,97	deleterious	-6,93	high_impact	3,96	damaging	0,13	damaging	0,01	deleterious	4,45	24,2	0,22	0,45	disease	0,69	disease	0,89	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	0,24	high_impact	2,61	0,53	0,8	68,28	19,43	P	0,72	P	0,94	disease_causing	0,56	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7989	7989	T	G	MI.6051	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	404	135	L	R	cTc/cGc	-0,4	0	0	probably_damaging	1	neutral	0,37	neutral	1,49	deleterious	-3,84	deleterious	-5,94	medium_impact	3,15	damaging	0,15	damaging	0,01	deleterious	4,34	24	0,19	0,45	disease	0,55	disease	0,92	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,85	low_impact	-3,52	medium_impact	0,08	medium_impact	1,85	0,55	0,8	68,28	19,43	P	0,78	P	0,99	disease_causing	0,7	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7991	7991	C	T	MI.6052	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	406	136	L	F	Ctt/Ttt	-8,01	0	0	probably_damaging	1	neutral	0,71	neutral	0,98	deleterious	-4,76	deleterious	-3,96	medium_impact	2,9	damaging	0,12	damaging	0,02	deleterious	4,07	23,7	0,45	0,55	disease	0,71	disease	0,75	disease	0,66	disease	0,65	3	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,83	low_impact	-3,52	medium_impact	0,42	medium_impact	1,61	0,57	0,8	68,72	19,58	P	0,65	P	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7991	7991	C	G	MI.6053	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	406	136	L	V	Ctt/Gtt	-8,01	0	0	probably_damaging	0,99	neutral	0,57	neutral	1,04	deleterious	-3,71	deleterious	-2,97	medium_impact	3,02	damaging	0,14	damaging	0,01	deleterious	3,55	23,1	0,45	0,55	neutral	0,44	disease	0,74	disease	0,53	disease	0,6	2	deleterious	0,99	neutral	0,29	deleterious	1	deleterious	0,78	low_impact	-2,58	medium_impact	0,27	medium_impact	1,73	0,63	0,8	68,72	19,58	P	0,58	P	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7991	7991	C	A	MI.6054	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	406	136	L	I	Ctt/Att	-8,01	0	0	probably_damaging	1	neutral	0,43	neutral	1,05	deleterious	-3,56	neutral	-1,98	medium_impact	2,52	damaging	0,18	damaging	0,03	deleterious	4,27	24	0,41	0,5	neutral	0,24	disease	0,67	neutral	0,47	neutral	0,22	6	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,72	low_impact	-3,52	medium_impact	0,14	medium_impact	1,26	0,71	0,85	68,72	19,58	P	0,64	P	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7992	7992	T	A	MI.6055	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	407	136	L	H	cTt/cAt	-2,48	0	0	probably_damaging	1	neutral	0,54	neutral	0,93	deleterious	-7,03	deleterious	-6,93	high_impact	4,61	damaging	0,13	damaging	0,01	deleterious	4,19	23,8	0,22	0,45	disease	0,78	disease	0,89	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	0,24	high_impact	3,22	0,55	0,8	68,72	19,58	P	0,66	P	0,94	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7992	7992	T	G	MI.6056	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	407	136	L	R	cTt/cGt	-2,48	0	0	probably_damaging	1	neutral	0,51	neutral	0,94	deleterious	-6,03	deleterious	-5,94	high_impact	3,71	damaging	0,15	damaging	0,01	deleterious	4,28	24	0,21	0,45	disease	0,83	disease	0,91	disease	0,78	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,21	high_impact	2,37	0,6	0,8	68,72	19,58	P	0,71	P	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7992	7992	T	C	MI.6057	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	407	136	L	P	cTt/cCt	-2,48	0	0	probably_damaging	1	neutral	0,31	neutral	0,93	deleterious	-6,86	deleterious	-6,93	high_impact	4,61	damaging	0,14	damaging	0,02	deleterious	4	23,6	0,18	0,45	disease	0,87	disease	0,86	disease	0,67	disease	0,64	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	0,01	high_impact	3,22	0,44	0,8	68,72	19,58	P	0,65	P	0,99	disease_causing	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7994	7994	G	T	MI.6058	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	409	137	D	Y	Gac/Tac	-0,17	0,61	0	possibly_damaging	0,73	neutral	0,61	neutral	1,77	deleterious	-3,92	deleterious	-4,8	medium_impact	3,17	neutral	0,62	neutral	0,57	deleterious	3,82	23,4	0,31	0,45	disease	0,6	disease	0,89	disease	0,67	disease	0,72	4	neutral	0,69	neutral	0,44	NA	0	deleterious	0,71	low_impact	-1,12	medium_impact	0,31	medium_impact	1,87	0,35	0,8	64,76	16,86	N	0,3	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7994	7994	G	C	MI.6059	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	409	137	D	H	Gac/Cac	-0,17	0,61	0	possibly_damaging	0,57	neutral	0,38	neutral	1,79	neutral	-2,95	deleterious	-2,88	medium_impact	2,48	neutral	0,61	neutral	0,5	deleterious	3,39	23	0,39	0,5	neutral	0,49	disease	0,84	disease	0,66	disease	0,71	4	neutral	0,64	neutral	0,41	NA	0	deleterious	0,57	medium_impact	-0,84	medium_impact	0,09	medium_impact	1,22	0,59	0,8	64,76	16,86	N	0,29	N	0,51	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8812	8812	A	T	MI.606	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	286	96	T	S	Acc/Tcc	-13,52	0	0,01	probably_damaging	0,99	neutral	1	neutral	4,57	neutral	1,33	deleterious	-3,07	low_impact	1,12	neutral	0,71	neutral	0,67	deleterious	2,7	20,8	0,52	0,65	neutral	0,4	neutral	0,13	neutral	0,33	neutral	0,25	5	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,67	low_impact	-2,65	high_impact	1,98	medium_impact	-0,14	0,73	0,9	34,51	7,56	N	0,3	N	0,88	polymorphism	0,97	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7994	7994	G	A	MI.6060	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	409	137	D	N	Gac/Aac	-0,17	0,61	0	benign	0,15	neutral	0,57	neutral	1,85	neutral	-1,44	neutral	-2,44	low_impact	1,86	damaging	0,58	neutral	0,59	deleterious	2,45	19,15	0,71	0,75	neutral	0,34	disease	0,78	disease	0,51	disease	0,57	1	neutral	0,32	deleterious	0,71	neutral	-6	neutral	0,31	medium_impact	-0,02	medium_impact	0,27	medium_impact	0,64	0,76	0,85	64,76	16,86	N	0,3	N	0,45	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7995	7995	A	G	MI.6061	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	410	137	D	G	gAc/gGc	9,29	1	0	benign	0,14	neutral	0,46	neutral	1,81	neutral	-2,25	deleterious	-4,42	low_impact	1,75	damaging	0,58	neutral	0,51	deleterious	2,32	18,29	0,37	0,5	neutral	0,45	disease	0,84	disease	0,63	disease	0,7	4	neutral	0,46	deleterious	0,66	neutral	-6	neutral	0,29	medium_impact	0,01	medium_impact	0,17	medium_impact	0,54	0,46	0,8	64,76	16,86	N	0,52	P	0,86	disease_causing	0,87	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7995	7995	A	C	MI.6062	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	410	137	D	A	gAc/gCc	9,29	1	0	benign	0,1	neutral	0,81	neutral	1,88	neutral	-1,08	deleterious	-3,77	low_impact	1,18	neutral	0,63	neutral	0,65	deleterious	1,95	15,89	0,32	0,5	neutral	0,2	disease	0,85	disease	0,61	disease	0,7	4	neutral	0,09	deleterious	0,86	neutral	-6	neutral	0,25	medium_impact	0,17	medium_impact	0,55	medium_impact	0	0,36	0,8	64,76	16,86	P	0,48	N	0,59	disease_causing	0,83	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7995	7995	A	T	MI.6063	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	410	137	D	V	gAc/gTc	9,29	1	0	benign	0,38	neutral	0,56	neutral	1,79	neutral	-2,99	deleterious	-4,73	low_impact	1,52	damaging	0,59	neutral	0,62	deleterious	2,21	17,58	0,32	0,5	neutral	0,25	disease	0,9	disease	0,63	disease	0,72	4	neutral	0,38	deleterious	0,59	neutral	-6	neutral	0,36	medium_impact	-0,52	medium_impact	0,26	medium_impact	0,32	0,38	0,8	64,76	16,86	N	0,45	N	0,82	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7996	7996	C	G	MI.6064	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	411	137	D	E	gaC/gaG	8,59	1	0	benign	0	neutral	1	neutral	2,19	neutral	0,91	neutral	1,56	neutral_impact	-1,04	neutral	0,85	neutral	0,95	neutral	-0,7	0,07	0,61	0,65	neutral	0,36	neutral	0,24	neutral	0,18	neutral	0,44	1	neutral	0	deleterious	1	neutral	-6	neutral	0,16	high_impact	2,08	high_impact	1,86	low_impact	-2,08	0,44	0,8	64,76	16,86	N	0,49	N	0,01	polymorphism	0,87	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7996	7996	C	A	MI.6065	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	411	137	D	E	gaC/gaA	8,59	1	0	benign	0	neutral	1	neutral	2,19	neutral	0,91	neutral	1,56	neutral_impact	-1,04	neutral	0,85	neutral	0,95	neutral	-0,34	0,55	0,61	0,65	neutral	0,36	neutral	0,24	neutral	0,18	neutral	0,44	1	neutral	0	deleterious	1	neutral	-6	neutral	0,16	high_impact	2,08	high_impact	1,86	low_impact	-2,08	0,44	0,8	64,76	16,86	N	0,5	N	0,01	polymorphism	0,87	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7997	7997	G	A	MI.6066	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	412	138	V	I	Gtt/Att	1,68	1	0	probably_damaging	0,99	neutral	0,22	neutral	1,76	neutral	-1,25	neutral	-0,99	high_impact	4,45	damaging	0,44	damaging	0,11	deleterious	3,78	23,4	0,67	0,7	disease	0,59	disease	0,59	disease	0,73	disease	0,69	4	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,68	low_impact	-2,58	medium_impact	-0,1	high_impact	3,07	0,75	0,85	68,72	19,45	P	0,67	P	0,3	disease_causing	0,52	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7997	7997	G	C	MI.6067	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	412	138	V	L	Gtt/Ctt	1,68	1	0	probably_damaging	0,99	neutral	0,39	neutral	1,71	neutral	-1,6	deleterious	-2,53	medium_impact	3,48	damaging	0,41	damaging	0,12	deleterious	3,66	23,2	0,54	0,6	disease	0,53	disease	0,76	disease	0,7	disease	0,66	3	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,76	low_impact	-2,58	medium_impact	0,1	high_impact	2,16	0,65	0,8	68,72	19,45	P	0,64	P	0,23	disease_causing	0,79	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7997	7997	G	T	MI.6068	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	412	138	V	F	Gtt/Ttt	1,68	1	0	probably_damaging	1	neutral	0,12	neutral	1,65	neutral	-2,35	deleterious	-4,29	high_impact	4,45	damaging	0,38	damaging	0,11	deleterious	3,96	23,6	0,21	0,45	disease	0,72	disease	0,87	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	-0,27	high_impact	3,07	0,7	0,85	68,72	19,45	P	0,68	P	0,94	disease_causing	0,98	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7998	7998	T	A	MI.6069	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	413	138	V	D	gTt/gAt	3,29	1	0	probably_damaging	1	neutral	0,65	neutral	1,57	deleterious	-4,9	deleterious	-5,69	high_impact	3,75	damaging	0,38	damaging	0,11	deleterious	4,52	24,3	0,15	0,4	disease	0,65	disease	0,9	disease	0,8	disease	0,73	5	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,81	low_impact	-3,52	medium_impact	0,35	high_impact	2,41	0,55	0,8	68,72	19,45	P	0,68	P	0,9	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8812	8812	A	G	MI.607	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	286	96	T	A	Acc/Gcc	-13,52	0	0,01	probably_damaging	0,99	neutral	0,14	neutral	4,56	neutral	1,25	deleterious	-3,89	low_impact	1,88	neutral	0,84	neutral	0,67	deleterious	3,88	23,5	0,62	0,7	neutral	0,28	neutral	0,31	neutral	0,42	neutral	0,42	2	deleterious	0,99	neutral	0,08	neutral	-2	deleterious	0,67	low_impact	-2,65	medium_impact	-0,15	medium_impact	0,51	0,43	0,9	34,51	7,56	N	0,4	N	0,63	polymorphism	0,93	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7998	7998	T	G	MI.6070	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	413	138	V	G	gTt/gGt	3,29	1	0	probably_damaging	1	neutral	0,39	neutral	1,58	deleterious	-4,34	deleterious	-5,7	high_impact	3,64	damaging	0,45	damaging	0,14	deleterious	3,92	23,5	0,27	0,45	neutral	0,36	disease	0,83	disease	0,76	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,74	low_impact	-3,52	medium_impact	0,1	high_impact	2,31	0,32	0,8	68,72	19,45	N	0,52	P	0,84	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	7998	7998	T	C	MI.6071	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	413	138	V	A	gTt/gCt	3,29	1	0	probably_damaging	1	neutral	0,76	neutral	1,64	neutral	-2,58	deleterious	-2,81	medium_impact	3,06	neutral	0,71	neutral	0,61	deleterious	2,33	18,37	0,54	0,6	neutral	0,49	disease	0,71	disease	0,66	neutral	0,36	3	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,75	low_impact	-3,52	medium_impact	0,48	medium_impact	1,76	0,38	0,8	68,72	19,45	N	0,39	N	0,59	disease_causing	0,93	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8000	8000	G	A	MI.6072	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	415	139	D	N	Gac/Aac	-11,7	0	0	probably_damaging	1	neutral	0,37	neutral	1,66	neutral	-2,58	deleterious	-4,37	medium_impact	2,96	damaging	0,2	damaging	0,02	deleterious	4,3	24	0,66	0,7	disease	0,54	disease	0,85	disease	0,65	disease	0,55	1	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,81	low_impact	-3,52	medium_impact	0,08	medium_impact	1,67	0,74	0,85	68,72	19,59	P	0,65	P	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8000	8000	G	T	MI.6073	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	415	139	D	Y	Gac/Tac	-11,7	0	0	probably_damaging	1	neutral	1	neutral	1,63	deleterious	-3,35	deleterious	-8,49	high_impact	4,06	damaging	0,17	damaging	0,02	deleterious	4,01	23,6	0,27	0,45	disease	0,78	disease	0,94	disease	0,75	disease	0,75	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,88	low_impact	-3,52	high_impact	1,86	high_impact	2,7	0,27	0,8	68,72	19,59	N	0,44	N	0,99	polymorphism	0,98	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8000	8000	G	C	MI.6074	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	415	139	D	H	Gac/Cac	-11,7	0	0	probably_damaging	1	neutral	0,56	neutral	1,61	deleterious	-3,89	deleterious	-6,49	high_impact	4,26	damaging	0,12	damaging	0,02	deleterious	3,71	23,3	0,35	0,5	disease	0,69	disease	0,9	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	0,26	high_impact	2,89	0,44	0,8	68,72	19,59	P	0,55	P	0,98	polymorphism	0,99	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8001	8001	A	T	MI.6075	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	416	139	D	V	gAc/gTc	6,06	1	0	probably_damaging	1	neutral	0,55	neutral	1,62	deleterious	-3,59	deleterious	-8,53	high_impact	4,61	damaging	0,12	damaging	0,01	deleterious	3,86	23,5	0,31	0,45	neutral	0,36	disease	0,94	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-3,52	medium_impact	0,25	high_impact	3,22	0,22	0,8	68,72	19,59	P	0,75	P	0,99	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8001	8001	A	C	MI.6076	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	416	139	D	A	gAc/gCc	6,06	1	0	probably_damaging	1	neutral	0,57	neutral	1,67	neutral	-2,47	deleterious	-7,5	medium_impact	2,4	damaging	0,23	damaging	0,1	deleterious	3,78	23,4	0,35	0,5	neutral	0,26	disease	0,9	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,78	low_impact	-3,52	medium_impact	0,27	medium_impact	1,15	0,37	0,8	68,72	19,59	P	0,78	P	0,96	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8001	8001	A	G	MI.6077	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	416	139	D	G	gAc/gGc	6,06	1	0	probably_damaging	1	neutral	0,36	neutral	1,63	deleterious	-3,31	deleterious	-6,43	high_impact	3,63	damaging	0,12	damaging	0,03	deleterious	4,13	23,8	0,34	0,5	disease	0,54	disease	0,88	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,52	medium_impact	0,07	high_impact	2,3	0,32	0,8	68,72	19,59	P	0,86	P	0,97	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8002	8002	C	G	MI.6078	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	417	139	D	E	gaC/gaG	6,98	1	0	probably_damaging	0,98	neutral	0,4	neutral	1,72	neutral	-1,72	deleterious	-3,75	high_impact	3,81	damaging	0,17	damaging	0,03	deleterious	3,97	23,6	0,53	0,6	neutral	0,42	disease	0,85	disease	0,61	disease	0,68	4	deleterious	0,98	neutral	0,21	deleterious	2	deleterious	0,8	low_impact	-2,3	medium_impact	0,11	high_impact	2,47	0,54	0,8	68,72	19,59	P	0,88	P	0,95	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8002	8002	C	A	MI.6079	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	417	139	D	E	gaC/gaA	6,98	1	0	probably_damaging	0,98	neutral	0,4	neutral	1,72	neutral	-1,72	deleterious	-3,75	high_impact	3,81	damaging	0,17	damaging	0,03	deleterious	4,29	24	0,53	0,6	neutral	0,42	disease	0,85	disease	0,61	disease	0,68	4	deleterious	0,98	neutral	0,21	deleterious	2	deleterious	0,8	low_impact	-2,3	medium_impact	0,11	high_impact	2,47	0,54	0,8	68,72	19,59	P	0,88	P	0,95	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8812	8812	A	C	MI.608	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	286	96	T	P	Acc/Ccc	-13,52	0	0,01	probably_damaging	1	deleterious	0,01	neutral	4,28	neutral	-2,58	deleterious	-5,06	medium_impact	3,41	damaging	0,58	neutral	0,47	deleterious	3,93	23,5	0,22	0,65	disease	0,84	disease	0,76	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,83	0,52	0,9	34,51	7,56	N	0,34	N	0,99	polymorphism	0,71	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8003	8003	A	G	MI.6080	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	418	140	N	D	Aat/Gat	-2,01	0	0	probably_damaging	0,99	neutral	0,29	neutral	1,67	neutral	-2,11	deleterious	-3,25	medium_impact	3,5	damaging	0,51	damaging	0,16	deleterious	3,39	23	0,67	0,7	disease	0,66	disease	0,78	disease	0,66	disease	0,66	3	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,77	low_impact	-2,58	medium_impact	-0,01	high_impact	2,18	0,5	0,8	67,84	19,51	N	0,34	N	0,97	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8003	8003	A	T	MI.6081	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	418	140	N	Y	Aat/Tat	-2,01	0	0	probably_damaging	1	neutral	1	neutral	1,58	deleterious	-4,84	deleterious	-2,85	medium_impact	3,15	damaging	0,56	damaging	0,23	deleterious	3,21	22,7	0,32	0,5	disease	0,86	disease	0,85	disease	0,66	disease	0,61	2	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,84	low_impact	-3,52	high_impact	1,86	medium_impact	1,85	0,37	0,8	67,84	19,51	N	0,22	N	0,98	polymorphism	0,94	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8003	8003	A	C	MI.6082	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	418	140	N	H	Aat/Cat	-2,01	0	0	probably_damaging	1	neutral	0,58	neutral	1,61	deleterious	-3,35	neutral	1,18	medium_impact	2,1	neutral	0,7	neutral	0,67	deleterious	0,66	8,58	0,53	0,6	neutral	0,46	disease	0,58	neutral	0,45	neutral	0,16	7	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,74	low_impact	-3,52	medium_impact	0,28	medium_impact	0,86	0,41	0,8	67,84	19,51	N	0,3	N	0,94	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8004	8004	A	C	MI.6083	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	419	140	N	T	aAt/aCt	3,52	0,99	0	probably_damaging	0,99	neutral	0,4	neutral	1,63	neutral	-2,75	deleterious	-4,1	medium_impact	2,35	damaging	0,52	damaging	0,2	deleterious	3,11	22,5	0,48	0,55	disease	0,62	disease	0,78	disease	0,58	disease	0,54	1	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,79	low_impact	-2,58	medium_impact	0,11	medium_impact	1,1	0,4	0,8	67,84	19,51	N	0,41	N	0,92	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8004	8004	A	G	MI.6084	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	419	140	N	S	aAt/aGt	3,52	0,99	0	probably_damaging	0,97	neutral	0,41	neutral	1,67	neutral	-2,22	deleterious	-3,11	medium_impact	2,55	damaging	0,55	damaging	0,2	neutral	1,43	12,96	0,71	0,75	disease	0,56	disease	0,8	disease	0,58	disease	0,55	1	neutral	0,97	neutral	0,22	deleterious	1	deleterious	0,78	low_impact	-2,13	medium_impact	0,12	medium_impact	1,29	0,31	0,8	67,84	19,51	N	0,39	N	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8004	8004	A	T	MI.6085	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	419	140	N	I	aAt/aTt	3,52	0,99	0	probably_damaging	1	neutral	0,4	neutral	1,57	deleterious	-5,76	deleterious	-5,95	medium_impact	3,5	damaging	0,57	damaging	0,16	deleterious	3,82	23,4	0,3	0,45	disease	0,84	disease	0,88	disease	0,67	disease	0,63	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,84	low_impact	-3,52	medium_impact	0,11	high_impact	2,18	0,27	0,8	67,84	19,51	N	0,42	N	0,97	polymorphism	0,96	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8005	8005	T	G	MI.6086	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	420	140	N	K	aaT/aaG	6,98	1	0	probably_damaging	1	neutral	0,29	neutral	1,65	neutral	-2,4	deleterious	-3,66	medium_impact	2,6	damaging	0,51	damaging	0,14	deleterious	3,92	23,5	0,63	0,65	neutral	0,47	disease	0,86	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	-0,01	medium_impact	1,33	0,59	0,8	67,84	19,51	P	0,53	P	0,99	polymorphism	0,94	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8005	8005	T	A	MI.6087	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	420	140	N	K	aaT/aaA	6,98	1	0	probably_damaging	1	neutral	0,29	neutral	1,65	neutral	-2,4	deleterious	-3,66	medium_impact	2,6	damaging	0,51	damaging	0,14	deleterious	4,14	23,8	0,63	0,65	neutral	0,47	disease	0,86	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	-0,01	medium_impact	1,33	0,59	0,8	67,84	19,51	P	0,55	P	0,99	polymorphism	0,94	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8006	8006	C	T	MI.6088	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	421	141	R	W	Cga/Tga	-7,32	0	0	probably_damaging	1	neutral	0,19	neutral	1,78	deleterious	-5,54	deleterious	-7,53	high_impact	3,55	damaging	0,33	damaging	0,1	deleterious	5,26	25,7	0,3	0,45	disease	0,94	disease	0,91	disease	0,71	disease	0,61	2	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	-0,14	high_impact	2,22	0,71	0,85	68,28	19	N	0,46	N	1	polymorphism	0,99	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8006	8006	C	G	MI.6089	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	421	141	R	G	Cga/Gga	-7,32	0	0	probably_damaging	1	neutral	0,34	neutral	1,82	neutral	-2,36	deleterious	-6,49	high_impact	3,55	damaging	0,3	damaging	0,23	deleterious	4,29	24	0,25	0,45	neutral	0,45	disease	0,84	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,79	low_impact	-3,52	medium_impact	0,05	high_impact	2,22	0,31	0,8	68,28	19	N	0,5	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8813	8813	C	A	MI.609	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	287	96	T	N	aCc/aAc	8,69	1	0	probably_damaging	1	deleterious	0,01	neutral	4,34	neutral	-0,67	deleterious	-4,13	high_impact	3,62	neutral	0,67	neutral	0,54	deleterious	3,64	23,2	0,43	0,65	neutral	0,38	disease	0,66	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,71	low_impact	-3,6	medium_impact	-0,84	high_impact	2,01	0,77	0,9	34,51	7,56	P	0,52	P	0,9	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8007	8007	G	A	MI.6090	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	422	141	R	Q	cGa/cAa	4,44	0,99	0	probably_damaging	1	neutral	0,29	neutral	1,87	neutral	-0,76	deleterious	-3,66	medium_impact	3,21	damaging	0,34	damaging	0,13	deleterious	4,57	24,4	0,34	0,5	disease	0,53	disease	0,85	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	-0,01	medium_impact	1,9	0,74	0,85	68,28	19	P	0,75	P	1	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8007	8007	G	T	MI.6091	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	422	141	R	L	cGa/cTa	4,44	0,99	0	probably_damaging	1	neutral	0,66	neutral	1,83	neutral	-2,23	deleterious	-6,62	medium_impact	3,12	damaging	0,29	damaging	0,27	deleterious	4,36	24,1	0,27	0,45	disease	0,69	disease	0,92	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,86	low_impact	-3,52	medium_impact	0,36	medium_impact	1,82	0,25	0,8	68,28	19	P	0,88	P	1	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8007	8007	G	C	MI.6092	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	422	141	R	P	cGa/cCa	4,44	0,99	0	probably_damaging	1	neutral	0,2	neutral	1,83	neutral	-0,51	deleterious	-6,55	low_impact	1,89	damaging	0,33	damaging	0,14	deleterious	4,31	24	0,14	0,4	disease	0,75	disease	0,91	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,13	medium_impact	0,67	0,29	0,8	68,28	19	P	0,63	P	1	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8009	8009	G	T	MI.6093	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	424	142	V	L	Gta/Tta	-1,55	0	0	probably_damaging	0,97	neutral	0,74	neutral	2,22	neutral	1,1	neutral	-0,07	neutral_impact	-1,06	neutral	0,75	neutral	0,87	deleterious	2,59	20,1	0,47	0,55	neutral	0,4	neutral	0,36	neutral	0,43	neutral	0,45	1	neutral	0,97	neutral	0,39	neutral	-2	deleterious	0,67	low_impact	-2,13	medium_impact	0,46	low_impact	-2,1	0,85	0,9	31,72	28,73	N	0,27	N	0,23	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8009	8009	G	A	MI.6094	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	424	142	V	M	Gta/Ata	-1,55	0	0	probably_damaging	1	neutral	0,32	neutral	1,93	neutral	-1,36	neutral	1,6	neutral_impact	-0,7	neutral	0,75	neutral	0,79	neutral	1,08	11,11	0,52	0,6	neutral	0,48	neutral	0,13	neutral	0,33	neutral	0,2	6	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,69	low_impact	-3,52	medium_impact	0,02	low_impact	-1,76	0,78	0,85	31,72	28,73	N	0,48	N	0,87	disease_causing_automatic	0	0	rs199474826	Pathogenic	Familial_colorectal_cancer	RCV000010295.2	MedGen	colorectal tumor	.	.	.	.	.	.	.	.	.
chrM	8009	8009	G	C	MI.6095	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	424	142	V	L	Gta/Cta	-1,55	0	0	probably_damaging	0,97	neutral	0,74	neutral	2,22	neutral	1,1	neutral	-0,07	neutral_impact	-1,06	neutral	0,75	neutral	0,87	deleterious	2,46	19,18	0,47	0,55	neutral	0,4	neutral	0,36	neutral	0,43	neutral	0,45	1	neutral	0,97	neutral	0,39	neutral	-2	deleterious	0,67	low_impact	-2,13	medium_impact	0,46	low_impact	-2,1	0,85	0,9	31,72	28,73	N	0,27	N	0,23	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8010	8010	T	A	MI.6096	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	425	142	V	E	gTa/gAa	0,52	0,09	0	probably_damaging	1	neutral	0,27	neutral	1,87	deleterious	-4,31	deleterious	-3,75	medium_impact	2,74	damaging	0,58	neutral	0,43	deleterious	5,04	25,2	0,12	0,4	disease	0,78	disease	0,8	disease	0,77	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,86	low_impact	-3,52	medium_impact	-0,03	medium_impact	1,46	0,44	0,8	31,72	28,73	N	0,38	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8010	8010	T	C	MI.6097	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	425	142	V	A	gTa/gCa	0,52	0,09	0	probably_damaging	1	neutral	0,51	neutral	1,91	neutral	-2,16	neutral	-2,43	low_impact	1,54	neutral	0,74	neutral	0,88	deleterious	2,57	19,9	0,4	0,5	neutral	0,34	neutral	0,33	disease	0,52	neutral	0,46	1	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,71	low_impact	-3,52	medium_impact	0,21	medium_impact	0,34	0,63	0,8	31,72	28,73	N	0,4	N	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	T8010C	Developmental delay,ataxia,seizure,hypotonia,lactic acidosis	-	+	Reported	1
chrM	8010	8010	T	G	MI.6098	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	425	142	V	G	gTa/gGa	0,52	0,09	0	probably_damaging	1	neutral	0,36	neutral	1,87	deleterious	-4,06	deleterious	-4,74	medium_impact	2,39	neutral	0,61	neutral	0,57	deleterious	3,96	23,6	0,15	0,4	disease	0,76	disease	0,61	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,79	low_impact	-3,52	medium_impact	0,07	medium_impact	1,14	0,64	0,8	31,72	28,73	N	0,35	N	0,84	disease_causing	0,78	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8012	8012	G	C	MI.6099	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	427	143	V	L	Gta/Cta	-10,32	0	0	probably_damaging	0,97	neutral	0,48	neutral	1,78	neutral	-2,75	deleterious	-2,6	medium_impact	2,34	damaging	0,5	neutral	0,47	deleterious	3,61	23,2	0,38	0,5	disease	0,55	disease	0,7	disease	0,6	disease	0,55	1	neutral	0,97	neutral	0,26	deleterious	1	deleterious	0,75	low_impact	-2,13	medium_impact	0,19	medium_impact	1,09	0,77	0,85	69,16	16,28	N	0,35	N	0,23	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8553	8553	C	A	MI.61	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	27	9	F	L	ttC/ttA	7,53	1	0	probably_damaging	0,92	neutral	0,06	neutral	3,94	neutral	-0,84	deleterious	-5,27	medium_impact	2,34	damaging	0,57	neutral	0,59	deleterious	8,72	35	0,4	0,65	disease	0,6	disease	0,77	disease	0,82	disease	0,8	6	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,76	low_impact	-1,76	medium_impact	-0,38	medium_impact	0,91	0,44	0,9	49,56	8,77	P	0,59	P	0,89	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8813	8813	C	G	MI.610	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	287	96	T	S	aCc/aGc	8,69	1	0	probably_damaging	0,99	neutral	1	neutral	4,57	neutral	1,33	deleterious	-3,07	low_impact	1,12	neutral	0,71	neutral	0,67	deleterious	2,43	19,03	0,52	0,65	neutral	0,4	neutral	0,13	neutral	0,33	neutral	0,25	5	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,67	low_impact	-2,65	high_impact	1,98	medium_impact	-0,14	0,73	0,9	34,51	7,56	N	0,46	N	0,88	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8012	8012	G	A	MI.6100	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	427	143	V	M	Gta/Ata	-10,32	0	0	probably_damaging	1	neutral	0,24	neutral	1,7	deleterious	-4,06	deleterious	-2,73	medium_impact	2,77	damaging	0,53	neutral	0,49	deleterious	3,78	23,4	0,38	0,5	disease	0,7	disease	0,65	neutral	0,49	neutral	0,33	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,77	low_impact	-3,52	medium_impact	-0,07	medium_impact	1,49	0,71	0,85	69,16	16,28	N	0,38	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8012	8012	G	T	MI.6101	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	427	143	V	L	Gta/Tta	-10,32	0	0	probably_damaging	0,97	neutral	0,48	neutral	1,78	neutral	-2,75	deleterious	-2,6	medium_impact	2,34	damaging	0,5	neutral	0,47	deleterious	3,77	23,4	0,38	0,5	disease	0,55	disease	0,7	disease	0,6	disease	0,55	1	neutral	0,97	neutral	0,26	deleterious	1	deleterious	0,75	low_impact	-2,13	medium_impact	0,19	medium_impact	1,09	0,77	0,85	69,16	16,28	N	0,35	N	0,23	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8013	8013	T	A	MI.6102	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	428	143	V	E	gTa/gAa	3,52	1	0	probably_damaging	1	neutral	1	neutral	1,71	deleterious	-3,76	deleterious	-5,71	high_impact	3,58	damaging	0,43	neutral	0,34	deleterious	4,89	24,9	0,21	0,45	disease	0,84	disease	0,9	disease	0,74	disease	0,67	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,89	low_impact	-3,52	high_impact	1,86	high_impact	2,25	0,43	0,8	69,16	16,28	P	0,63	P	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8013	8013	T	G	MI.6103	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	428	143	V	G	gTa/gGa	3,52	1	0	probably_damaging	1	neutral	0,41	neutral	1,68	deleterious	-4,78	deleterious	-6,69	high_impact	4,13	damaging	0,55	neutral	0,53	deleterious	3,89	23,5	0,28	0,45	disease	0,84	disease	0,82	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	0,12	high_impact	2,77	0,33	0,8	69,16	16,28	N	0,45	N	0,84	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8013	8013	T	C	MI.6104	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	428	143	V	A	gTa/gCa	3,52	1	0	probably_damaging	1	neutral	0,78	neutral	1,76	deleterious	-3,04	deleterious	-3,77	medium_impact	2,88	damaging	0,55	neutral	0,57	deleterious	3,68	23,3	0,38	0,5	neutral	0,47	disease	0,67	disease	0,62	disease	0,57	1	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,75	low_impact	-3,52	medium_impact	0,51	medium_impact	1,6	0,4	0,8	69,16	16,28	N	0,43	N	0,59	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8015	8015	C	A	MI.6105	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	430	144	L	I	Ctc/Atc	-20	0	0	probably_damaging	0,99	neutral	0,45	neutral	1,67	neutral	-1,12	neutral	0,62	neutral_impact	0,62	neutral	0,75	neutral	0,66	deleterious	2,18	17,37	0,38	0,5	neutral	0,27	neutral	0,44	neutral	0,24	neutral	0,43	1	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,71	low_impact	-2,58	medium_impact	0,16	medium_impact	-0,52	0,81	0,85	68,28	18,94	N	0,4	N	0,63	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8015	8015	C	T	MI.6106	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	430	144	L	F	Ctc/Ttc	-20	0	0	probably_damaging	1	neutral	0,7	neutral	1,47	deleterious	-3,86	neutral	-2,29	medium_impact	2,52	damaging	0,42	damaging	0,15	deleterious	4,04	23,7	0,44	0,55	neutral	0,49	disease	0,72	disease	0,52	neutral	0,46	1	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	0,41	medium_impact	1,26	0,71	0,85	68,28	18,94	N	0,3	N	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8015	8015	C	G	MI.6107	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	430	144	L	V	Ctc/Gtc	-20	0	0	probably_damaging	0,98	neutral	0,66	neutral	1,71	neutral	-0,58	neutral	0,75	neutral_impact	0,66	neutral	0,75	neutral	0,66	deleterious	0,79	9,43	0,46	0,55	neutral	0,32	neutral	0,47	neutral	0,25	neutral	0,43	1	deleterious	0,98	neutral	0,34	neutral	-2	deleterious	0,74	low_impact	-2,3	medium_impact	0,36	medium_impact	-0,49	0,74	0,85	68,28	18,94	N	0,32	N	0,66	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8016	8016	T	A	MI.6108	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	431	144	L	H	cTc/cAc	-3,63	0	0	probably_damaging	1	neutral	0,51	neutral	1,4	deleterious	-6,46	deleterious	-4,37	high_impact	3,96	damaging	0,46	damaging	0,15	deleterious	4,41	24,1	0,13	0,4	disease	0,93	disease	0,87	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	0,21	high_impact	2,61	0,52	0,8	68,28	18,94	N	0,35	N	0,94	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8016	8016	T	G	MI.6109	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	431	144	L	R	cTc/cGc	-3,63	0	0	probably_damaging	1	neutral	0,39	neutral	1,41	deleterious	-5,86	deleterious	-3,95	high_impact	3,96	damaging	0,35	damaging	0,12	deleterious	4,29	24	0,13	0,4	disease	0,9	disease	0,92	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,93	low_impact	-3,52	medium_impact	0,1	high_impact	2,61	0,4	0,8	68,28	18,94	N	0,48	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8813	8813	C	T	MI.611	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	287	96	T	I	aCc/aTc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	4,29	neutral	-2,13	deleterious	-5,08	high_impact	3,96	neutral	0,71	neutral	0,6	deleterious	3,97	23,6	0,39	0,65	disease	0,89	disease	0,72	disease	0,7	disease	0,7	4	deleterious	1	deleterious	0	deleterious	6	deleterious	0,79	low_impact	-3,6	low_impact	-1,4	high_impact	2,3	0,74	0,9	34,51	7,56	P	0,52	P	0,97	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8016	8016	T	C	MI.6110	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	431	144	L	P	cTc/cCc	-3,63	0	0	probably_damaging	1	neutral	0,3	neutral	1,4	deleterious	-6,34	deleterious	-3,83	high_impact	3,96	damaging	0,33	damaging	0,09	deleterious	4,06	23,7	0,14	0,4	disease	0,92	disease	0,9	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,93	low_impact	-3,52	medium_impact	0	high_impact	2,61	0,35	0,8	68,28	18,94	N	0,4	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8018	8018	C	G	MI.6111	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	433	145	P	A	Ccg/Gcg	-11,24	0	0	probably_damaging	1	neutral	0,51	neutral	0,38	deleterious	-5,98	deleterious	-7,84	high_impact	4,38	damaging	0,15	damaging	0,11	deleterious	3,15	22,6	0,22	0,45	disease	0,88	disease	0,84	disease	0,74	disease	0,66	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,21	high_impact	3	0,6	0,8	68,28	19,5	P	0,58	P	0,9	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8018	8018	C	T	MI.6112	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	433	145	P	S	Ccg/Tcg	-11,24	0	0	probably_damaging	1	neutral	0,42	neutral	0,37	deleterious	-6,42	deleterious	-7,83	high_impact	4,72	damaging	0,11	damaging	0,03	deleterious	3,98	23,6	0,27	0,45	disease	0,91	disease	0,9	disease	0,74	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	0,13	high_impact	3,32	0,21	0,8	68,28	19,5	P	0,58	P	0,94	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8018	8018	C	A	MI.6113	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	433	145	P	T	Ccg/Acg	-11,24	0	0	probably_damaging	1	neutral	0,41	neutral	0,35	deleterious	-7	deleterious	-7,84	high_impact	4,17	damaging	0,12	damaging	0,02	deleterious	3,75	23,3	0,25	0,45	disease	0,92	disease	0,89	disease	0,75	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	0,12	high_impact	2,8	0,58	0,8	68,28	19,5	P	0,51	P	0,96	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8019	8019	C	A	MI.6114	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	434	145	P	Q	cCg/cAg	5,6	1	0	probably_damaging	1	neutral	0,31	neutral	0,35	deleterious	-7,07	deleterious	-7,84	high_impact	4,38	damaging	0,11	damaging	0,03	deleterious	4,16	23,8	0,17	0,45	disease	0,97	disease	0,9	disease	0,77	disease	0,66	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	0,01	high_impact	3	0,52	0,8	68,28	19,5	P	0,8	P	0,88	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8019	8019	C	G	MI.6115	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	434	145	P	R	cCg/cGg	5,6	1	0	probably_damaging	1	neutral	0,4	neutral	0,35	deleterious	-7,24	deleterious	-8,82	high_impact	4,72	damaging	0,12	damaging	0,02	deleterious	3,7	23,3	0,2	0,45	disease	0,97	disease	0,94	disease	0,83	disease	0,68	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,93	low_impact	-3,52	medium_impact	0,11	high_impact	3,32	0,44	0,8	68,28	19,5	P	0,77	P	0,85	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8019	8019	C	T	MI.6116	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	434	145	P	L	cCg/cTg	5,6	1	0	probably_damaging	1	neutral	0,68	neutral	0,36	deleterious	-6,5	deleterious	-9,8	high_impact	3,83	damaging	0,08	damaging	0,02	deleterious	4,51	24,3	0,26	0,45	disease	0,84	disease	0,91	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,39	high_impact	2,49	0,64	0,8	68,28	19,5	P	0,73	P	0,92	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8021	8021	A	G	MI.6117	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	436	146	I	V	Att/Gtt	-10,08	0	0	benign	0	neutral	0,7	neutral	2,12	neutral	2,31	neutral	0,27	neutral_impact	-1,06	neutral	0,89	neutral	0,96	neutral	-0,25	0,87	0,71	0,75	neutral	0,36	neutral	0,29	neutral	0,2	neutral	0,45	1	neutral	0,29	deleterious	0,85	neutral	-6	neutral	0,14	high_impact	2,08	medium_impact	0,41	low_impact	-2,1	0,28	0,8	29,07	74,35	N	0,37	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	A8021G	Asthenozoospermia	+	-	Reported	1
chrM	8021	8021	A	C	MI.6118	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	436	146	I	L	Att/Ctt	-10,08	0	0	benign	0,04	neutral	0,88	neutral	2,04	neutral	0,27	neutral	0,18	neutral_impact	-0,04	neutral	0,71	neutral	0,64	deleterious	0,86	9,83	0,52	0,6	neutral	0,36	neutral	0,37	neutral	0,19	neutral	0,46	1	neutral	0,05	deleterious	0,92	neutral	-6	neutral	0,16	medium_impact	0,57	medium_impact	0,68	low_impact	-1,14	0,55	0,8	29,07	74,35	N	0,37	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8021	8021	A	T	MI.6119	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	436	146	I	F	Att/Ttt	-10,08	0	0	benign	0,38	neutral	0,7	neutral	1,99	neutral	-1,49	neutral	-1,42	neutral_impact	-0,96	neutral	0,69	neutral	0,53	deleterious	2,45	19,12	0,58	0,65	neutral	0,29	neutral	0,44	neutral	0,18	neutral	0,43	1	neutral	0,29	deleterious	0,66	neutral	-6	neutral	0,4	medium_impact	-0,52	medium_impact	0,41	low_impact	-2,01	0,42	0,8	29,07	74,35	N	0,35	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8815	8815	C	A	MI.612	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	289	97	Q	K	Caa/Aaa	-10,28	0	0	probably_damaging	0,97	deleterious	0,01	neutral	4,35	neutral	-0,52	deleterious	-3,44	high_impact	3,98	damaging	0,58	damaging	0,14	deleterious	3,97	23,6	0,53	0,65	neutral	0,46	disease	0,76	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,75	low_impact	-2,19	medium_impact	-0,84	high_impact	2,31	0,66	0,9	48,23	8,28	N	0,3	N	0,99	polymorphism	0,65	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8022	8022	T	A	MI.6120	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	437	146	I	N	aTt/aAt	1,91	0	0	possibly_damaging	0,8	neutral	0,56	neutral	1,93	neutral	-1,21	deleterious	-2,67	low_impact	0,84	neutral	0,68	neutral	0,46	deleterious	4,31	24	0,38	0,5	disease	0,71	disease	0,7	neutral	0,42	neutral	0,45	1	neutral	0,76	neutral	0,38	neutral	-3	deleterious	0,69	low_impact	-1,28	medium_impact	0,26	medium_impact	-0,32	0,36	0,8	29,07	74,35	N	0,23	N	0,48	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8022	8022	T	G	MI.6121	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	437	146	I	S	aTt/aGt	1,91	0	0	possibly_damaging	0,46	neutral	0,68	neutral	1,97	neutral	0,14	neutral	-1,59	neutral_impact	-0,2	neutral	0,68	neutral	0,61	deleterious	2,31	18,2	0,41	0,5	disease	0,55	disease	0,66	neutral	0,27	neutral	0,26	5	neutral	0,37	deleterious	0,61	neutral	-3	neutral	0,37	medium_impact	-0,66	medium_impact	0,39	low_impact	-1,29	0,33	0,8	29,07	74,35	N	0,25	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8022	8022	T	C	MI.6122	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	437	146	I	T	aTt/aCt	1,91	0	0	benign	0,2	neutral	0,68	neutral	2	neutral	0,58	neutral	-0,5	neutral_impact	-0,56	neutral	0,82	neutral	0,91	deleterious	0,08	3,44	0,55	0,6	neutral	0,26	neutral	0,34	neutral	0,23	neutral	0,44	1	neutral	0,21	deleterious	0,74	neutral	-6	neutral	0,21	medium_impact	-0,16	medium_impact	0,39	low_impact	-1,63	0,19	0,8	29,07	74,35	N	0,28	N	0,36	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8023	8023	T	A	MI.6123	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	438	146	I	M	atT/atA	0,06	0	0	possibly_damaging	0,66	neutral	0,38	neutral	1,97	neutral	-1,13	neutral	1,59	neutral_impact	-1,36	neutral	0,75	neutral	0,97	deleterious	0,79	9,42	0,74	0,8	neutral	0,34	neutral	0,08	neutral	0,11	neutral	0,26	5	neutral	0,69	neutral	0,36	neutral	-3	neutral	0,39	medium_impact	-0,99	medium_impact	0,09	low_impact	-2,38	0,65	0,8	29,07	74,35	N	0,52	P	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8023	8023	T	G	MI.6124	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	438	146	I	M	atT/atG	0,06	0	0	possibly_damaging	0,66	neutral	0,38	neutral	1,97	neutral	-1,13	neutral	1,59	neutral_impact	-1,36	neutral	0,75	neutral	0,97	deleterious	0,46	7,14	0,74	0,8	neutral	0,34	neutral	0,08	neutral	0,11	neutral	0,26	5	neutral	0,69	neutral	0,36	neutral	-3	neutral	0,39	medium_impact	-0,99	medium_impact	0,09	low_impact	-2,38	0,65	0,8	29,07	74,35	N	0,52	P	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8024	8024	G	C	MI.6125	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	439	147	E	Q	Gaa/Caa	-0,17	0	0	benign	0,08	neutral	0,61	neutral	1,95	neutral	-0,88	neutral	-1,92	neutral_impact	0,43	neutral	0,68	neutral	0,63	deleterious	0,21	4,75	0,4	0,5	neutral	0,47	neutral	0,29	neutral	0,18	neutral	0,45	1	neutral	0,3	deleterious	0,77	neutral	-6	neutral	0,22	medium_impact	0,27	medium_impact	0,31	medium_impact	-0,7	0,77	0,85	67,4	18,75	N	0,39	N	0,76	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8024	8024	G	A	MI.6126	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	439	147	E	K	Gaa/Aaa	-0,17	0	0	benign	0	neutral	0,92	neutral	2	neutral	-0,01	deleterious	-2,66	neutral_impact	-0,47	neutral	0,62	damaging	0,26	neutral	1,56	13,64	0,3	0,45	neutral	0,34	disease	0,69	neutral	0,24	neutral	0,24	5	neutral	0,06	deleterious	0,96	neutral	-6	neutral	0,21	high_impact	2,08	medium_impact	0,79	low_impact	-1,55	0,8	0,85	67,4	18,75	N	0,24	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8025	8025	A	T	MI.6127	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	440	147	E	V	gAa/gTa	1,91	0,97	0	benign	0,23	neutral	0,39	neutral	1,91	deleterious	-3,07	deleterious	-5,17	medium_impact	2,16	damaging	0,59	neutral	0,4	deleterious	2,56	19,85	0,23	0,45	disease	0,56	disease	0,75	neutral	0,48	disease	0,51	0	neutral	0,53	deleterious	0,58	neutral	-3	neutral	0,31	medium_impact	-0,23	medium_impact	0,1	medium_impact	0,92	0,71	0,85	67,4	18,75	N	0,41	N	0,82	disease_causing	0,88	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8025	8025	A	G	MI.6128	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	440	147	E	G	gAa/gGa	1,91	0,97	0	benign	0,17	neutral	0,43	neutral	2,17	neutral	1,5	deleterious	-3,57	neutral_impact	-1,38	neutral	0,66	neutral	0,75	neutral	1,41	12,83	0,26	0,45	neutral	0,28	disease	0,54	neutral	0,36	neutral	0,22	6	neutral	0,49	deleterious	0,63	neutral	-6	neutral	0,26	medium_impact	-0,08	medium_impact	0,14	low_impact	-2,4	0,46	0,8	67,4	18,75	N	0,37	N	0,64	disease_causing	0,78	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8025	8025	A	C	MI.6129	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	440	147	E	A	gAa/gCa	1,91	0,97	0	benign	0,11	neutral	0,81	neutral	1,95	neutral	-0,84	deleterious	-3,86	low_impact	1,61	neutral	0,61	neutral	0,52	deleterious	1,92	15,73	0,25	0,45	neutral	0,46	disease	0,53	neutral	0,4	neutral	0,46	1	neutral	0,09	deleterious	0,85	neutral	-6	neutral	0,23	medium_impact	0,13	medium_impact	0,55	medium_impact	0,4	0,64	0,8	67,4	18,75	N	0,38	N	0,66	disease_causing	0,75	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8815	8815	C	G	MI.613	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	289	97	Q	E	Caa/Gaa	-10,28	0	0	probably_damaging	0,94	neutral	0,09	neutral	4,35	neutral	-0,45	deleterious	-2,58	high_impact	3,98	neutral	0,6	damaging	0,14	deleterious	3,05	22,4	0,47	0,65	neutral	0,48	disease	0,65	disease	0,7	disease	0,66	3	neutral	0,98	neutral	0,08	deleterious	2	deleterious	0,73	low_impact	-1,89	medium_impact	-0,28	high_impact	2,31	0,55	0,9	48,23	8,28	N	0,34	N	0,94	polymorphism	0,79	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8026	8026	A	C	MI.6130	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	441	147	E	D	gaA/gaC	4,67	0,98	0	benign	0	neutral	0,62	neutral	2,09	neutral	0,97	neutral	-1,17	neutral_impact	0,1	neutral	0,76	neutral	0,73	deleterious	0,59	8,11	0,34	0,5	neutral	0,35	neutral	0,47	neutral	0,19	neutral	0,37	3	neutral	0,38	deleterious	0,81	neutral	-6	neutral	0,17	high_impact	2,08	medium_impact	0,32	low_impact	-1,01	0,75	0,85	67,4	18,75	N	0,47	N	0,81	disease_causing	0,59	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8026	8026	A	T	MI.6131	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	441	147	E	D	gaA/gaT	4,67	0,98	0	benign	0	neutral	0,62	neutral	2,09	neutral	0,97	neutral	-1,17	neutral_impact	0,1	neutral	0,76	neutral	0,73	deleterious	0,75	9,14	0,34	0,5	neutral	0,35	neutral	0,47	neutral	0,19	neutral	0,37	3	neutral	0,38	deleterious	0,81	neutral	-6	neutral	0,17	high_impact	2,08	medium_impact	0,32	low_impact	-1,01	0,75	0,85	67,4	18,75	N	0,48	N	0,81	disease_causing	0,59	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8027	8027	G	T	MI.6132	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	442	148	A	S	Gcc/Tcc	-0,4	0	0,01	probably_damaging	1	neutral	0,82	neutral	2,03	neutral	0,01	neutral	1,57	neutral_impact	-0,54	neutral	0,73	neutral	0,73	neutral	1,08	11,08	0,54	0,6	neutral	0,28	neutral	0,11	neutral	0,31	neutral	0,25	5	deleterious	1	neutral	0,41	neutral	-2	deleterious	0,66	low_impact	-3,52	medium_impact	0,57	low_impact	-1,61	0,84	0,9	30,4	66	N	0,28	N	0,44	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8027	8027	G	A	MI.6133	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	442	148	A	T	Gcc/Acc	-0,4	0	0,01	probably_damaging	1	neutral	0,61	neutral	2,05	neutral	0,95	neutral	0,15	neutral_impact	-1,17	neutral	0,95	neutral	0,78	deleterious	2,81	21,4	0,59	0,65	neutral	0,29	neutral	0,1	neutral	0,29	neutral	0,21	6	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,64	low_impact	-3,52	medium_impact	0,31	low_impact	-2,2	0,61	0,8	30,4	66	N	0,31	N	0,09	polymorphism	1	0	rs1116904	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8027	8027	G	C	MI.6134	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	442	148	A	P	Gcc/Ccc	-0,4	0	0,01	probably_damaging	1	neutral	0,33	neutral	1,92	neutral	-2,15	neutral	-2,02	medium_impact	2	damaging	0,55	neutral	0,36	deleterious	3,94	23,5	0,28	0,45	disease	0,61	disease	0,78	disease	0,6	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,83	low_impact	-3,52	medium_impact	0,04	medium_impact	0,77	0,84	0,9	30,4	66	N	0,28	N	0,61	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8028	8028	C	A	MI.6135	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	443	148	A	D	gCc/gAc	0,06	0	0	probably_damaging	1	neutral	0,63	neutral	1,99	neutral	-0,55	neutral	-1,63	low_impact	1,09	damaging	0,57	neutral	0,43	deleterious	4,76	24,7	0,28	0,45	neutral	0,41	disease	0,72	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,76	low_impact	-3,52	medium_impact	0,33	medium_impact	-0,08	0,76	0,85	30,4	66	N	0,26	N	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8028	8028	C	G	MI.6136	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	443	148	A	G	gCc/gGc	0,06	0	0	probably_damaging	1	neutral	0,39	neutral	1,93	neutral	-1,57	neutral	-1,56	low_impact	1,65	neutral	0,65	neutral	0,66	deleterious	4,12	23,8	0,51	0,6	disease	0,53	neutral	0,44	disease	0,6	disease	0,52	0	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,72	low_impact	-3,52	medium_impact	0,1	medium_impact	0,44	0,84	0,9	30,4	66	N	0,35	N	0,36	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8028	8028	C	T	MI.6137	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	443	148	A	V	gCc/gTc	0,06	0	0	probably_damaging	1	neutral	0,31	neutral	1,99	neutral	-0,88	neutral	-1,76	neutral_impact	0,02	neutral	0,75	neutral	0,78	deleterious	3,45	23	0,53	0,6	neutral	0,28	disease	0,5	neutral	0,46	neutral	0,25	5	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,7	low_impact	-3,52	medium_impact	0,01	low_impact	-1,09	0,68	0,85	30,4	66	N	0,35	N	0,21	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8030	8030	C	G	MI.6138	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	445	149	P	A	Ccc/Gcc	-10,55	0	0	benign	0,33	neutral	0,76	neutral	2,02	neutral	-1,84	deleterious	-5,46	low_impact	1,88	damaging	0,59	neutral	0,64	neutral	1,47	13,17	0,44	0,55	disease	0,63	neutral	0,4	neutral	0,37	disease	0,62	2	neutral	0,22	deleterious	0,72	neutral	-6	neutral	0,43	medium_impact	-0,43	medium_impact	0,48	medium_impact	0,66	0,54	0,8	29,96	51,16	N	0,3	N	0,61	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8030	8030	C	A	MI.6139	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	445	149	P	T	Ccc/Acc	-10,55	0	0	possibly_damaging	0,57	neutral	0,58	neutral	2	neutral	-1,33	deleterious	-5,09	low_impact	1,4	neutral	0,74	neutral	0,97	deleterious	2,28	18,06	0,39	0,5	neutral	0,44	neutral	0,43	neutral	0,36	neutral	0,43	1	neutral	0,52	deleterious	0,51	neutral	-3	deleterious	0,51	medium_impact	-0,84	medium_impact	0,28	medium_impact	0,21	0,51	0,8	29,96	51,16	N	0,38	N	0,12	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8816	8816	A	G	MI.614	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	290	97	Q	R	cAa/cGa	7,3	1	0	probably_damaging	0,97	deleterious	0,02	neutral	4,3	neutral	-1,27	deleterious	-3,47	high_impact	3,98	neutral	0,63	damaging	0,16	deleterious	3,47	23	0,48	0,65	disease	0,59	disease	0,79	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,81	low_impact	-2,19	medium_impact	-0,66	high_impact	2,31	0,54	0,9	48,23	8,28	P	0,51	P	0,91	disease_causing	1	0,11	rs1057520102	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8030	8030	C	T	MI.6140	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	445	149	P	S	Ccc/Tcc	-10,55	0	0	benign	0,07	neutral	0,74	neutral	2,04	neutral	-1,67	deleterious	-5,38	low_impact	1,69	neutral	0,69	neutral	0,76	neutral	0,97	10,48	0,57	0,65	disease	0,62	disease	0,53	neutral	0,25	neutral	0,28	4	neutral	0,17	deleterious	0,84	neutral	-6	neutral	0,25	medium_impact	0,33	medium_impact	0,46	medium_impact	0,48	0,23	0,8	29,96	51,16	N	0,28	N	0,57	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8031	8031	C	A	MI.6141	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	446	149	P	H	cCc/cAc	1,68	0,79	0	probably_damaging	0,95	neutral	0,13	neutral	1,99	neutral	-1,75	deleterious	-6,7	low_impact	1,12	damaging	0,55	neutral	0,53	deleterious	4,06	23,7	0,37	0,5	disease	0,57	disease	0,57	neutral	0,34	neutral	0,28	4	neutral	0,98	neutral	0,09	neutral	-2	deleterious	0,73	low_impact	-1,91	medium_impact	-0,25	medium_impact	-0,06	0,38	0,8	29,96	51,16	N	0,36	N	0,81	disease_causing	0,89	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8031	8031	C	T	MI.6142	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	446	149	P	L	cCc/cTc	1,68	0,79	0	possibly_damaging	0,76	neutral	0,34	neutral	1,96	neutral	-2,96	deleterious	-7,17	low_impact	1,5	neutral	0,64	neutral	0,54	deleterious	4,27	23,9	0,42	0,55	disease	0,51	disease	0,52	neutral	0,35	neutral	0,29	4	neutral	0,8	neutral	0,29	neutral	-3	deleterious	0,61	low_impact	-1,19	medium_impact	0,05	medium_impact	0,3	0,62	0,8	29,96	51,16	N	0,38	N	0,91	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8031	8031	C	G	MI.6143	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	446	149	P	R	cCc/cGc	1,68	0,79	0	possibly_damaging	0,88	neutral	0,53	neutral	2,01	neutral	-1,44	deleterious	-6,63	low_impact	1,74	damaging	0,45	neutral	0,34	deleterious	3,56	23,1	0,37	0,5	neutral	0,5	disease	0,74	neutral	0,47	neutral	0,48	0	neutral	0,86	neutral	0,33	neutral	-3	deleterious	0,71	low_impact	-1,53	medium_impact	0,23	medium_impact	0,53	0,37	0,8	29,96	51,16	N	0,34	N	0,9	disease_causing	0,94	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8033	8033	A	C	MI.6144	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	448	150	I	L	Att/Ctt	-11,47	0	0	benign	0	neutral	0,36	neutral	1,83	neutral	-2,19	neutral	-1,66	medium_impact	2,49	damaging	0,56	neutral	0,39	deleterious	2	16,23	0,33	0,5	disease	0,64	disease	0,56	disease	0,55	neutral	0,49	0	neutral	0,64	deleterious	0,68	neutral	-3	neutral	0,25	high_impact	2,08	medium_impact	0,07	medium_impact	1,23	0,73	0,85	27,75	40,03	N	0,36	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8033	8033	A	G	MI.6145	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	448	150	I	V	Att/Gtt	-11,47	0	0	benign	0	neutral	0,33	neutral	2,11	neutral	1,58	neutral	-0,37	neutral_impact	0,77	neutral	0,85	neutral	0,92	neutral	-0,44	0,32	0,46	0,55	neutral	0,28	neutral	0,21	neutral	0,35	neutral	0,35	3	neutral	0,67	deleterious	0,67	neutral	-6	neutral	0,16	high_impact	2,08	medium_impact	0,04	medium_impact	-0,38	0,56	0,8	27,75	40,03	N	0,42	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8033	8033	A	T	MI.6146	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	448	150	I	F	Att/Ttt	-11,47	0	0	benign	0,08	neutral	0,06	neutral	1,69	deleterious	-3,82	deleterious	-3,49	high_impact	3,62	damaging	0,48	neutral	0,28	deleterious	2,42	18,92	0,24	0,45	disease	0,91	disease	0,74	disease	0,67	disease	0,68	4	neutral	0,93	deleterious	0,49	neutral	-2	deleterious	0,44	medium_impact	0,27	medium_impact	-0,46	high_impact	2,29	0,68	0,85	27,75	40,03	N	0,32	N	0,86	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8034	8034	T	G	MI.6147	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	449	150	I	S	aTt/aGt	1,21	0,38	0	possibly_damaging	0,68	neutral	0,74	neutral	1,69	deleterious	-4,82	deleterious	-4,56	medium_impact	2,89	damaging	0,55	neutral	0,36	deleterious	4,37	24,1	0,16	0,45	disease	0,93	disease	0,84	disease	0,6	disease	0,69	4	neutral	0,61	deleterious	0,53	NA	0	deleterious	0,54	low_impact	-1,03	medium_impact	0,46	medium_impact	1,6	0,48	0,8	27,75	40,03	N	0,29	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8034	8034	T	A	MI.6148	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	449	150	I	N	aTt/aAt	1,21	0,38	0	possibly_damaging	0,88	neutral	0,49	neutral	1,67	deleterious	-6,02	deleterious	-5,58	medium_impact	3,48	damaging	0,54	neutral	0,28	deleterious	4,48	24,2	0,12	0,4	disease	0,96	disease	0,79	disease	0,68	disease	0,72	4	neutral	0,86	neutral	0,31	NA	0	deleterious	0,85	low_impact	-1,53	medium_impact	0,2	high_impact	2,16	0,56	0,8	27,75	40,03	N	0,31	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8034	8034	T	C	MI.6149	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	449	150	I	T	aTt/aCt	1,21	0,38	0	benign	0,32	neutral	0,57	neutral	1,72	neutral	-2,89	deleterious	-3,11	low_impact	1,42	neutral	0,69	neutral	0,77	deleterious	2,15	17,15	0,29	0,45	disease	0,6	disease	0,54	neutral	0,45	neutral	0,23	5	neutral	0,34	deleterious	0,63	neutral	-6	neutral	0,32	medium_impact	-0,42	medium_impact	0,27	medium_impact	0,23	0,5	0,8	27,75	40,03	N	0,27	N	0,87	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8816	8816	A	T	MI.615	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	290	97	Q	L	cAa/cTa	7,3	1	0	probably_damaging	0,97	deleterious	0,04	neutral	4,27	neutral	-2,14	deleterious	-6,09	medium_impact	2,7	neutral	0,61	damaging	0,12	deleterious	3,8	23,4	0,32	0,65	disease	0,71	disease	0,77	disease	0,66	disease	0,59	2	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,78	low_impact	-2,19	medium_impact	-0,49	medium_impact	1,22	0,36	0,9	48,23	8,28	P	0,48	N	0,99	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8035	8035	T	A	MI.6150	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	450	150	I	M	atT/atA	4,67	0,8	0	benign	0,11	neutral	0,11	neutral	1,71	deleterious	-4,33	neutral	-2,31	medium_impact	2,73	damaging	0,59	neutral	0,39	deleterious	3,41	23	0,32	0,5	disease	0,89	disease	0,57	disease	0,56	disease	0,63	3	neutral	0,88	deleterious	0,5	neutral	-3	neutral	0,32	medium_impact	0,13	medium_impact	-0,3	medium_impact	1,45	0,72	0,85	27,75	40,03	N	0,44	N	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8035	8035	T	G	MI.6151	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	450	150	I	M	atT/atG	4,67	0,8	0	benign	0,11	neutral	0,11	neutral	1,71	deleterious	-4,33	neutral	-2,31	medium_impact	2,73	damaging	0,59	neutral	0,39	deleterious	3,2	22,7	0,32	0,5	disease	0,89	disease	0,57	disease	0,56	disease	0,63	3	neutral	0,88	deleterious	0,5	neutral	-3	neutral	0,32	medium_impact	0,13	medium_impact	-0,3	medium_impact	1,45	0,72	0,85	27,75	40,03	N	0,45	N	0,72	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8036	8036	C	A	MI.6152	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	451	151	R	S	Cgt/Agt	-11,47	0	0	probably_damaging	1	neutral	0,82	neutral	1,8	neutral	-2,06	deleterious	-5,89	medium_impact	3,03	damaging	0,11	damaging	0,01	deleterious	4,67	24,5	0,23	0,45	disease	0,58	disease	0,83	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,41	deleterious	1	deleterious	0,83	low_impact	-3,52	medium_impact	0,57	medium_impact	1,74	0,43	0,8	68,72	19,92	P	0,64	P	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8036	8036	C	G	MI.6153	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	451	151	R	G	Cgt/Ggt	-11,47	0	0	probably_damaging	1	neutral	0,49	neutral	1,76	deleterious	-3,37	deleterious	-6,87	high_impact	3,63	damaging	0,12	damaging	0,02	deleterious	4,29	24	0,25	0,45	disease	0,51	disease	0,77	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,79	low_impact	-3,52	medium_impact	0,2	high_impact	2,3	0,37	0,8	68,72	19,92	P	0,59	P	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8036	8036	C	T	MI.6154	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	451	151	R	C	Cgt/Tgt	-11,47	0	0	probably_damaging	1	neutral	0,13	neutral	1,74	deleterious	-5,77	deleterious	-7,86	high_impact	3,98	damaging	0,13	damaging	0	deleterious	5,09	25,3	0,3	0,45	disease	0,93	disease	0,81	disease	0,79	disease	0,73	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	-0,25	high_impact	2,63	0,78	0,85	68,72	19,92	P	0,66	P	1	disease_causing	0,57	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8037	8037	G	A	MI.6155	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	452	151	R	H	cGt/cAt	3,52	0,99	0	probably_damaging	1	neutral	0,36	neutral	1,77	neutral	-2,89	deleterious	-4,91	high_impact	3,56	damaging	0,1	damaging	0	deleterious	4,45	24,2	0,41	0,5	disease	0,79	disease	0,8	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	0,07	high_impact	2,23	0,85	0,9	68,72	19,92	P	0,9	P	0,99	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8037	8037	G	T	MI.6156	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	452	151	R	L	cGt/cTt	3,52	0,99	0	probably_damaging	1	neutral	0,6	neutral	1,84	neutral	-2,16	deleterious	-6,88	medium_impact	2,94	damaging	0,11	damaging	0,01	deleterious	4,42	24,2	0,28	0,45	neutral	0,41	disease	0,87	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,81	low_impact	-3,52	medium_impact	0,3	medium_impact	1,65	0,26	0,8	68,72	19,92	P	0,85	P	1	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8037	8037	G	C	MI.6157	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	452	151	R	P	cGt/cCt	3,52	0,99	0	probably_damaging	1	neutral	0,34	neutral	1,76	deleterious	-4,05	deleterious	-6,88	high_impact	4,18	damaging	0,14	damaging	0,02	deleterious	4,29	24	0,16	0,45	disease	0,82	disease	0,85	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	0,05	high_impact	2,81	0,37	0,8	68,72	19,92	P	0,83	P	1	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8039	8039	A	T	MI.6158	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	454	152	M	L	Ata/Tta	-6,63	0	0	probably_damaging	0,91	neutral	0,83	neutral	2,2	neutral	2,2	neutral	-1,18	neutral_impact	-0,36	neutral	0,65	damaging	0,22	deleterious	2,36	18,56	0,41	0,5	neutral	0,45	disease	0,54	neutral	0,3	neutral	0,21	6	neutral	0,89	neutral	0,46	neutral	-2	deleterious	0,6	low_impact	-1,66	medium_impact	0,59	low_impact	-1,44	0,74	0,85	69,6	17,45	N	0,26	N	0,7	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8039	8039	A	G	MI.6159	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	454	152	M	V	Ata/Gta	-6,63	0	0	probably_damaging	0,94	neutral	1	neutral	2,21	neutral	1,61	neutral	-0,77	neutral_impact	0,32	neutral	0,72	neutral	0,89	deleterious	0,19	4,53	0,44	0,55	neutral	0,26	neutral	0,39	neutral	0,3	neutral	0,44	1	neutral	0,94	deleterious	0,53	neutral	-2	deleterious	0,65	low_impact	-1,83	high_impact	1,86	medium_impact	-0,81	0,77	0,85	69,6	17,45	N	0,3	N	0,89	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8816	8816	A	C	MI.616	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	290	97	Q	P	cAa/cCa	7,3	1	0	probably_damaging	0,98	deleterious	0,01	neutral	4,26	neutral	-2,69	deleterious	-4,92	high_impact	3,98	damaging	0,53	damaging	0,2	deleterious	3,24	22,8	0,18	0,65	disease	0,77	disease	0,83	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,85	low_impact	-2,36	medium_impact	-0,84	high_impact	2,31	0,56	0,9	48,23	8,28	P	0,56	P	0,98	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8039	8039	A	C	MI.6160	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	454	152	M	L	Ata/Cta	-6,63	0	0	probably_damaging	0,91	neutral	0,83	neutral	2,2	neutral	2,2	neutral	-1,18	neutral_impact	-0,36	neutral	0,65	damaging	0,22	deleterious	2,25	17,86	0,41	0,5	neutral	0,45	disease	0,54	neutral	0,3	neutral	0,21	6	neutral	0,89	neutral	0,46	neutral	-2	deleterious	0,6	low_impact	-1,66	medium_impact	0,59	low_impact	-1,44	0,74	0,85	69,6	17,45	N	0,26	N	0,7	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8040	8040	T	A	MI.6161	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	455	152	M	K	aTa/aAa	0,06	0	0	probably_damaging	0,97	neutral	0,31	neutral	1,93	neutral	-2,06	deleterious	-4,31	medium_impact	3,32	damaging	0,49	damaging	0,1	deleterious	4,02	23,6	0,09	0,4	disease	0,75	disease	0,83	disease	0,67	disease	0,72	4	neutral	0,98	neutral	0,17	deleterious	1	deleterious	0,84	low_impact	-2,13	medium_impact	0,01	high_impact	2,01	0,53	0,8	69,6	17,45	N	0,3	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8040	8040	T	C	MI.6162	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	455	152	M	T	aTa/aCa	0,06	0	0	probably_damaging	0,99	neutral	0,57	neutral	1,98	neutral	-0,27	deleterious	-3,12	medium_impact	2,63	neutral	0,66	neutral	0,32	deleterious	1,97	16,05	0,28	0,45	disease	0,56	disease	0,63	disease	0,51	neutral	0,19	6	deleterious	0,99	neutral	0,29	deleterious	1	deleterious	0,78	low_impact	-2,58	medium_impact	0,27	medium_impact	1,36	0,57	0,8	69,6	17,45	N	0,22	N	0,92	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8041	8041	A	T	MI.6163	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	456	152	M	I	atA/atT	5,83	0,88	0	probably_damaging	0,96	neutral	0,95	neutral	2,14	neutral	1,39	neutral	-0,92	neutral_impact	0,55	neutral	0,73	neutral	0,56	deleterious	1,92	15,74	0,41	0,5	neutral	0,34	neutral	0,28	neutral	0,28	neutral	0,45	1	neutral	0,96	deleterious	0,5	neutral	-2	deleterious	0,66	low_impact	-2,01	medium_impact	0,91	medium_impact	-0,59	0,85	0,9	69,6	17,45	N	0,43	N	0,78	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8041	8041	A	C	MI.6164	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	456	152	M	I	atA/atC	5,83	0,88	0	probably_damaging	0,96	neutral	0,95	neutral	2,14	neutral	1,39	neutral	-0,92	neutral_impact	0,55	neutral	0,73	neutral	0,56	deleterious	1,86	15,33	0,41	0,5	neutral	0,34	neutral	0,28	neutral	0,28	neutral	0,45	1	neutral	0,96	deleterious	0,5	neutral	-2	deleterious	0,66	low_impact	-2,01	medium_impact	0,91	medium_impact	-0,59	0,85	0,9	69,6	17,45	N	0,43	N	0,78	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8042	8042	A	C	MI.6165	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	457	153	M	L	Ata/Cta	-2,01	0	0	possibly_damaging	0,9	neutral	0,74	neutral	2,27	neutral	2,79	neutral	1,7	neutral_impact	-1,69	neutral	0,78	neutral	0,97	deleterious	0,75	9,12	0,52	0,6	neutral	0,39	neutral	0,18	neutral	0,33	neutral	0,26	5	neutral	0,88	neutral	0,42	neutral	-3	deleterious	0,55	low_impact	-1,61	medium_impact	0,46	low_impact	-2,69	0,49	0,8	28,63	71,78	N	0,27	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8042	8042	A	T	MI.6166	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	457	153	M	L	Ata/Tta	-2,01	0	0	possibly_damaging	0,9	neutral	0,74	neutral	2,27	neutral	2,79	neutral	1,7	neutral_impact	-1,69	neutral	0,78	neutral	0,97	deleterious	0,82	9,56	0,52	0,6	neutral	0,39	neutral	0,18	neutral	0,33	neutral	0,26	5	neutral	0,88	neutral	0,42	neutral	-3	deleterious	0,55	low_impact	-1,61	medium_impact	0,46	low_impact	-2,69	0,49	0,8	28,63	71,78	N	0,27	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8042	8042	A	G	MI.6167	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	457	153	M	V	Ata/Gta	-2,01	0	0	probably_damaging	0,94	neutral	0,5	neutral	2,07	neutral	1,25	neutral	-0,82	neutral_impact	0,02	neutral	0,62	neutral	0,29	deleterious	2,94	22	0,64	0,7	neutral	0,36	disease	0,55	neutral	0,43	neutral	0,17	7	neutral	0,93	neutral	0,28	neutral	-2	deleterious	0,65	low_impact	-1,83	medium_impact	0,21	low_impact	-1,09	0,52	0,8	28,63	71,78	N	0,3	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8043	8043	T	C	MI.6168	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	458	153	M	T	aTa/aCa	-2,24	0	0	probably_damaging	0,97	neutral	0,6	neutral	2,02	neutral	0,46	deleterious	-2,96	low_impact	1,19	neutral	0,6	neutral	0,3	deleterious	3,14	22,6	0,51	0,6	neutral	0,37	neutral	0,49	disease	0,64	disease	0,65	3	neutral	0,97	neutral	0,32	neutral	-2	deleterious	0,73	low_impact	-2,13	medium_impact	0,3	medium_impact	0,01	0,28	0,8	28,63	71,78	N	0,21	N	0,72	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8043	8043	T	A	MI.6169	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	458	153	M	K	aTa/aAa	-2,24	0	0	probably_damaging	0,97	neutral	0,85	neutral	2,02	neutral	0,48	deleterious	-4	low_impact	1,32	damaging	0,5	damaging	0,23	deleterious	4,2	23,9	0,3	0,45	neutral	0,47	disease	0,71	disease	0,7	disease	0,7	4	neutral	0,97	neutral	0,44	neutral	-2	deleterious	0,75	low_impact	-2,13	medium_impact	0,62	medium_impact	0,13	0,58	0,8	28,63	71,78	N	0,27	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8817	8817	A	C	MI.617	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	291	97	Q	H	caA/caC	8,69	1	0	probably_damaging	1	neutral	1	neutral	4,4	neutral	0,1	deleterious	-4,34	low_impact	1,16	neutral	0,65	damaging	0,18	deleterious	3,43	23	0,55	0,65	neutral	0,26	neutral	0,25	disease	0,54	neutral	0,4	2	deleterious	0,99	deleterious	0,5	neutral	-2	deleterious	0,72	low_impact	-3,6	high_impact	1,98	medium_impact	-0,1	0,72	0,9	48,23	8,28	N	0,44	N	0,97	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8044	8044	A	C	MI.6170	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	459	153	M	I	atA/atC	7,44	0,96	0	probably_damaging	0,96	neutral	0,42	neutral	2,13	neutral	1,85	neutral	0,12	neutral_impact	-0,38	neutral	0,77	neutral	0,68	deleterious	2,38	18,69	0,58	0,65	neutral	0,35	neutral	0,34	neutral	0,39	neutral	0,43	1	neutral	0,95	neutral	0,23	neutral	-2	deleterious	0,66	low_impact	-2,01	medium_impact	0,13	low_impact	-1,46	0,61	0,8	28,63	71,78	P	0,51	P	0,29	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8044	8044	A	T	MI.6171	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	459	153	M	I	atA/atT	7,44	0,96	0	probably_damaging	0,96	neutral	0,42	neutral	2,13	neutral	1,85	neutral	0,12	neutral_impact	-0,38	neutral	0,77	neutral	0,68	deleterious	2,44	19,07	0,58	0,65	neutral	0,35	neutral	0,34	neutral	0,39	neutral	0,43	1	neutral	0,95	neutral	0,23	neutral	-2	deleterious	0,66	low_impact	-2,01	medium_impact	0,13	low_impact	-1,46	0,61	0,8	28,63	71,78	P	0,52	P	0,29	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8045	8045	A	T	MI.6172	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	460	154	I	F	Att/Ttt	-0,17	0	0	probably_damaging	0,99	neutral	0,49	neutral	1,64	deleterious	-3,54	deleterious	-3,92	medium_impact	2,58	damaging	0,51	neutral	0,32	deleterious	3,85	23,4	0,19	0,45	disease	0,71	disease	0,7	disease	0,69	disease	0,69	4	deleterious	0,99	neutral	0,25	deleterious	1	deleterious	0,81	low_impact	-2,58	medium_impact	0,2	medium_impact	1,31	0,75	0,85	65,2	18,48	N	0,31	N	0,87	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8045	8045	A	G	MI.6173	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	460	154	I	V	Att/Gtt	-0,17	0	0	probably_damaging	0,97	neutral	1	neutral	2,08	neutral	0,29	neutral	-0,36	neutral_impact	0,27	neutral	0,7	neutral	0,88	deleterious	0,64	8,45	0,47	0,55	neutral	0,26	neutral	0,05	neutral	0,28	neutral	0,16	7	neutral	0,97	deleterious	0,52	neutral	-2	deleterious	0,62	low_impact	-2,13	high_impact	1,86	medium_impact	-0,85	0,71	0,85	65,2	18,48	N	0,33	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8045	8045	A	C	MI.6174	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	460	154	I	L	Att/Ctt	-0,17	0	0	probably_damaging	0,97	neutral	0,48	neutral	1,85	neutral	-0,74	neutral	-1,96	low_impact	1,53	damaging	0,59	neutral	0,36	deleterious	3,91	23,5	0,29	0,45	neutral	0,29	disease	0,52	disease	0,61	disease	0,65	3	neutral	0,96	neutral	0,26	neutral	-2	deleterious	0,66	low_impact	-2,13	medium_impact	0,19	medium_impact	0,33	0,79	0,85	65,2	18,48	N	0,31	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8046	8046	T	A	MI.6175	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	461	154	I	N	aTt/aAt	0,06	0,01	0	probably_damaging	1	neutral	0,22	neutral	1,62	deleterious	-4,84	deleterious	-6,54	high_impact	3,56	damaging	0,53	neutral	0,32	deleterious	4,65	24,5	0,15	0,4	disease	0,85	disease	0,78	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,1	high_impact	2,23	0,62	0,8	65,2	18,48	N	0,31	N	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8046	8046	T	G	MI.6176	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	461	154	I	S	aTt/aGt	0,06	0,01	0	probably_damaging	0,99	neutral	0,37	neutral	1,64	deleterious	-3,76	deleterious	-5,56	medium_impact	2,62	damaging	0,54	neutral	0,34	deleterious	4,41	24,1	0,18	0,45	disease	0,72	disease	0,77	disease	0,66	disease	0,7	4	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,83	low_impact	-2,58	medium_impact	0,08	medium_impact	1,35	0,56	0,8	65,2	18,48	N	0,26	N	0,89	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8046	8046	T	C	MI.6177	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	461	154	I	T	aTt/aCt	0,06	0,01	0	probably_damaging	0,99	neutral	0,55	neutral	1,69	neutral	-2,37	deleterious	-4,26	low_impact	1,3	neutral	0,66	neutral	0,35	deleterious	3,58	23,2	0,22	0,45	disease	0,52	disease	0,6	disease	0,58	disease	0,58	2	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,77	low_impact	-2,58	medium_impact	0,25	medium_impact	0,11	0,54	0,8	65,2	18,48	N	0,21	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8047	8047	T	A	MI.6178	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	462	154	I	M	atT/atA	7,44	0,96	0	probably_damaging	1	neutral	0,14	neutral	1,65	deleterious	-3,34	deleterious	-2,63	medium_impact	2,41	damaging	0,59	neutral	0,35	deleterious	3,83	23,4	0,27	0,45	neutral	0,29	disease	0,51	disease	0,58	disease	0,63	3	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,7	low_impact	-3,52	medium_impact	-0,23	medium_impact	1,15	0,82	0,85	65,2	18,48	P	0,53	P	0,69	polymorphism	1	0,04	rs386829022	Uncertain significance	not_provided	RCV000224635.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	8047	8047	T	G	MI.6179	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	462	154	I	M	atT/atG	7,44	0,96	0	probably_damaging	1	neutral	0,14	neutral	1,65	deleterious	-3,34	deleterious	-2,63	medium_impact	2,41	damaging	0,59	neutral	0,35	deleterious	3,53	23,1	0,27	0,45	neutral	0,29	disease	0,51	disease	0,58	disease	0,63	3	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,7	low_impact	-3,52	medium_impact	-0,23	medium_impact	1,15	0,82	0,85	65,2	18,48	P	0,52	P	0,69	polymorphism	1	0,04	rs386829022	Uncertain significance	not_provided	RCV000224635.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	8817	8817	A	T	MI.618	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	291	97	Q	H	caA/caT	8,69	1	0	probably_damaging	1	neutral	1	neutral	4,4	neutral	0,1	deleterious	-4,34	low_impact	1,16	neutral	0,65	damaging	0,18	deleterious	3,57	23,1	0,55	0,65	neutral	0,26	neutral	0,25	disease	0,54	neutral	0,4	2	deleterious	0,99	deleterious	0,5	neutral	-2	deleterious	0,72	low_impact	-3,6	high_impact	1,98	medium_impact	-0,1	0,72	0,9	48,23	8,28	N	0,44	N	0,97	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8048	8048	A	C	MI.6180	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	463	155	T	P	Aca/Cca	-6,4	0	0	probably_damaging	1	neutral	0,31	neutral	1,4	deleterious	-4,74	deleterious	-3,77	high_impact	3,75	damaging	0,49	damaging	0,16	deleterious	3,61	23,2	0,17	0,45	disease	0,83	disease	0,86	disease	0,76	disease	0,68	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	0,01	high_impact	2,41	0,54	0,8	27,75	60,5	N	0,39	N	0,61	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8048	8048	A	T	MI.6181	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	463	155	T	S	Aca/Tca	-6,4	0	0	probably_damaging	0,99	neutral	1	neutral	1,59	neutral	-1,72	neutral	-0,21	neutral_impact	0,32	neutral	0,75	neutral	0,97	deleterious	0,77	9,25	0,41	0,5	neutral	0,39	neutral	0,23	neutral	0,46	neutral	0,38	2	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,7	low_impact	-2,58	high_impact	1,86	medium_impact	-0,81	0,7	0,85	27,75	60,5	N	0,29	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8048	8048	A	G	MI.6182	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	463	155	T	A	Aca/Gca	-6,4	0	0	probably_damaging	0,99	neutral	0,93	neutral	1,54	neutral	-2,18	neutral	-2,26	medium_impact	3,12	damaging	0,57	damaging	0,26	deleterious	3,6	23,2	0,56	0,6	disease	0,61	disease	0,66	disease	0,7	disease	0,66	3	deleterious	0,99	deleterious	0,47	deleterious	1	deleterious	0,76	low_impact	-2,58	medium_impact	0,83	medium_impact	1,82	0,59	0,8	27,75	60,5	N	0,2	N	0,14	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8049	8049	C	T	MI.6183	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	464	155	T	M	aCa/aTa	1,21	0,86	0	probably_damaging	1	neutral	0,23	neutral	1,39	deleterious	-5,37	deleterious	-3,77	high_impact	4,09	damaging	0,55	damaging	0,2	deleterious	4,12	23,8	0,4	0,5	disease	0,84	disease	0,77	disease	0,78	disease	0,7	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,8	low_impact	-3,52	medium_impact	-0,09	high_impact	2,73	0,67	0,85	27,75	60,5	N	0,47	N	0,68	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8049	8049	C	A	MI.6184	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	464	155	T	K	aCa/aAa	1,21	0,86	0	probably_damaging	1	neutral	0,8	neutral	1,43	deleterious	-3,83	deleterious	-3,24	medium_impact	2,85	damaging	0,5	damaging	0,18	deleterious	4,55	24,4	0,24	0,45	neutral	0,32	disease	0,86	disease	0,8	disease	0,7	4	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,76	low_impact	-3,52	medium_impact	0,54	medium_impact	1,57	0,72	0,85	27,75	60,5	N	0,42	N	0,5	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8051	8051	T	C	MI.6185	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	466	156	S	P	Tca/Cca	-3,17	0	0	probably_damaging	1	neutral	0,32	neutral	1,39	deleterious	-5,46	deleterious	-2,87	high_impact	3,77	damaging	0,35	damaging	0,13	deleterious	4,13	23,8	0,18	0,45	disease	0,83	disease	0,91	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,93	low_impact	-3,52	medium_impact	0,02	high_impact	2,43	0,73	0,85	68,72	19,53	N	0,47	N	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8051	8051	T	A	MI.6186	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	466	156	S	T	Tca/Aca	-3,17	0	0	probably_damaging	0,99	neutral	0,61	neutral	1,47	deleterious	-3,66	neutral	-1,58	medium_impact	3,35	damaging	0,51	damaging	0,18	deleterious	3,94	23,5	0,23	0,45	disease	0,79	disease	0,63	disease	0,72	disease	0,69	4	deleterious	0,98	neutral	0,31	deleterious	1	deleterious	0,83	low_impact	-2,58	medium_impact	0,31	high_impact	2,04	0,8	0,85	68,72	19,53	N	0,29	N	0,53	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8051	8051	T	G	MI.6187	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	466	156	S	A	Tca/Gca	-3,17	0	0	probably_damaging	0,99	neutral	1	neutral	1,69	neutral	-1,36	neutral	1,14	neutral_impact	0,67	neutral	0,71	neutral	0,7	neutral	1,14	11,42	0,27	0,45	neutral	0,44	neutral	0,12	neutral	0,33	neutral	0,24	5	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,71	low_impact	-2,58	high_impact	1,86	medium_impact	-0,48	0,84	0,9	68,72	19,53	N	0,27	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8052	8052	C	G	MI.6188	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	467	156	S	W	tCa/tGa	4,21	1	0	probably_damaging	1	neutral	0,18	neutral	1,38	deleterious	-8,67	deleterious	-4,83	high_impact	4,32	damaging	0,44	damaging	0,2	deleterious	4,41	24,1	0,1	0,4	disease	0,62	disease	0,92	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,16	high_impact	2,95	0,36	0,8	68,72	19,53	P	0,58	P	1	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8052	8052	C	T	MI.6189	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	467	156	S	L	tCa/tTa	4,21	1	0	probably_damaging	1	neutral	0,74	neutral	1,42	deleterious	-5,36	deleterious	-3,17	high_impact	4,32	damaging	0,46	damaging	0,17	deleterious	4,7	24,6	0,12	0,4	disease	0,56	disease	0,82	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	0,46	high_impact	2,95	0,87	0,9	68,72	19,53	P	0,6	P	0,99	disease_causing	0,96	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8818	8818	C	A	MI.619	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	292	98	L	M	Cta/Ata	1,29	0,85	0,01	probably_damaging	1	neutral	0,1	neutral	4,16	neutral	-2,64	neutral	-1,72	medium_impact	2,65	damaging	0,53	damaging	0,16	deleterious	3,86	23,5	0,39	0,65	disease	0,78	neutral	0,26	neutral	0,47	disease	0,54	1	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	-0,25	medium_impact	1,17	0,81	0,9	48,67	8,57	N	0,42	N	0,96	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8054	8054	C	A	MI.6190	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	469	157	Q	K	Caa/Aaa	-14,24	0	0	probably_damaging	0,99	neutral	0,91	neutral	2,02	neutral	0,24	neutral	-1,15	neutral_impact	-0,34	damaging	0,57	damaging	0,25	deleterious	4,11	23,7	0,5	0,6	neutral	0,24	disease	0,6	neutral	0,37	neutral	0,41	2	deleterious	0,99	neutral	0,46	neutral	-2	deleterious	0,69	low_impact	-2,58	medium_impact	0,76	low_impact	-1,42	0,64	0,8	29,07	72,35	N	0,24	N	0,48	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8054	8054	C	G	MI.6191	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	469	157	Q	E	Caa/Gaa	-14,24	0	0	probably_damaging	0,97	neutral	1	neutral	2,08	neutral	0,15	neutral	2,3	neutral_impact	-1,68	neutral	0,74	neutral	0,96	deleterious	0,51	7,5	0,47	0,55	neutral	0,23	neutral	0,26	neutral	0,17	neutral	0,41	2	neutral	0,97	deleterious	0,52	neutral	-2	deleterious	0,66	low_impact	-2,13	high_impact	1,86	low_impact	-2,68	0,81	0,85	29,07	72,35	N	0,33	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8055	8055	A	T	MI.6192	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	470	157	Q	L	cAa/cTa	4,21	1	0	probably_damaging	0,99	neutral	0,7	neutral	1,98	neutral	-1,37	deleterious	-4,75	neutral_impact	-0,62	neutral	0,66	neutral	0,29	deleterious	3,75	23,3	0,34	0,5	disease	0,59	disease	0,57	neutral	0,36	neutral	0,35	3	deleterious	0,99	neutral	0,36	neutral	-2	deleterious	0,75	low_impact	-2,58	medium_impact	0,41	low_impact	-1,69	0,32	0,8	29,07	72,35	N	0,36	N	0,83	disease_causing	0,56	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8055	8055	A	C	MI.6193	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	470	157	Q	P	cAa/cCa	4,21	1	0	probably_damaging	0,99	neutral	0,35	neutral	1,92	neutral	-1,77	deleterious	-2,75	neutral_impact	0,3	damaging	0,51	damaging	0,2	deleterious	3,32	22,9	0,15	0,4	disease	0,66	disease	0,82	neutral	0,39	disease	0,59	2	deleterious	0,99	neutral	0,18	neutral	-2	deleterious	0,84	low_impact	-2,58	medium_impact	0,06	medium_impact	-0,82	0,41	0,8	29,07	72,35	N	0,44	N	0,75	disease_causing	0,62	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8055	8055	A	G	MI.6194	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	470	157	Q	R	cAa/cGa	4,21	1	0	probably_damaging	0,99	neutral	0,67	neutral	1,97	neutral	0,37	neutral	-2,03	neutral_impact	0,2	damaging	0,59	damaging	0,24	deleterious	3,48	23,1	0,51	0,6	neutral	0,39	disease	0,65	neutral	0,42	neutral	0,4	2	deleterious	0,99	neutral	0,34	neutral	-2	deleterious	0,75	low_impact	-2,58	medium_impact	0,38	medium_impact	-0,92	0,53	0,8	29,07	72,35	N	0,38	N	0,41	polymorphism	0,92	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8056	8056	A	C	MI.6195	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	471	157	Q	H	caA/caC	6,98	1	0	probably_damaging	1	neutral	0,46	neutral	1,92	neutral	-2,04	neutral	-1,93	neutral_impact	-0,28	neutral	0,73	neutral	0,28	deleterious	3,53	23,1	0,49	0,55	disease	0,62	neutral	0,44	neutral	0,27	disease	0,61	2	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,73	low_impact	-3,52	medium_impact	0,17	low_impact	-1,37	0,72	0,85	29,07	72,35	N	0,48	N	0,49	disease_causing	0,78	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8056	8056	A	T	MI.6196	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	471	157	Q	H	caA/caT	6,98	1	0	probably_damaging	1	neutral	0,46	neutral	1,92	neutral	-2,04	neutral	-1,93	neutral_impact	-0,28	neutral	0,73	neutral	0,28	deleterious	3,69	23,3	0,49	0,55	disease	0,62	neutral	0,44	neutral	0,27	disease	0,61	2	deleterious	1	neutral	0,23	neutral	-2	deleterious	0,73	low_impact	-3,52	medium_impact	0,17	low_impact	-1,37	0,72	0,85	29,07	72,35	N	0,5	N	0,49	disease_causing	0,78	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8057	8057	G	T	MI.6197	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	472	158	D	Y	Gac/Tac	0,75	0,99	0	probably_damaging	1	neutral	1	neutral	0,39	deleterious	-9,31	deleterious	-8,84	high_impact	4,7	damaging	0,16	damaging	0,02	deleterious	4,01	23,6	0,17	0,45	disease	0,98	disease	0,89	disease	0,81	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,93	low_impact	-3,52	high_impact	1,86	high_impact	3,3	0,39	0,8	68,72	19,58	P	0,61	P	0,99	disease_causing	0,99	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8057	8057	G	C	MI.6198	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	472	158	D	H	Gac/Cac	0,75	0,99	0	probably_damaging	1	neutral	0,6	neutral	0,4	deleterious	-8,44	deleterious	-6,87	high_impact	4,7	damaging	0,13	damaging	0,01	deleterious	3,74	23,3	0,27	0,45	disease	0,96	disease	0,82	disease	0,81	disease	0,7	4	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	0,3	high_impact	3,3	0,66	0,8	68,72	19,58	P	0,75	P	0,98	disease_causing	0,98	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8057	8057	G	A	MI.6199	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	472	158	D	N	Gac/Aac	0,75	0,99	0	probably_damaging	1	neutral	0,48	neutral	0,43	deleterious	-6,48	deleterious	-4,91	high_impact	3,66	damaging	0,15	damaging	0,01	deleterious	4,38	24,1	0,37	0,5	disease	0,88	disease	0,73	disease	0,77	disease	0,65	3	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	0,19	high_impact	2,33	0,81	0,85	68,72	19,58	P	0,86	P	0,99	disease_causing	0,93	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8554	8554	A	C	MI.62	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	28	10	I	L	Att/Ctt	-0,33	0	0	benign	0	neutral	0,11	neutral	4,72	neutral	0,19	neutral	-0,24	neutral_impact	0,46	neutral	0,81	neutral	0,79	neutral	-0,07	1,97	0,35	0,65	neutral	0,38	neutral	0,28	neutral	0,18	neutral	0,45	1	neutral	0,89	deleterious	0,56	neutral	-6	neutral	0,11	high_impact	2,09	medium_impact	-0,22	medium_impact	-0,7	0,27	0,9	27,43	16,7	P	0,56	P	0,39	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8818	8818	C	G	MI.620	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	292	98	L	V	Cta/Gta	1,29	0,85	0,01	probably_damaging	0,99	neutral	0,05	neutral	4,29	neutral	-0,85	deleterious	-2,53	medium_impact	2,95	damaging	0,39	damaging	0,14	deleterious	3,33	22,9	0,38	0,65	neutral	0,49	neutral	0,43	disease	0,62	neutral	0,45	1	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,71	low_impact	-2,65	medium_impact	-0,43	medium_impact	1,43	0,65	0,9	48,67	8,57	P	0,58	P	0,87	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8058	8058	A	G	MI.6200	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	473	158	D	G	gAc/gGc	5,13	1	0	probably_damaging	1	neutral	0,44	neutral	0,42	deleterious	-6,88	deleterious	-6,87	high_impact	4,36	damaging	0,14	damaging	0,02	deleterious	4,06	23,7	0,21	0,45	disease	0,75	disease	0,81	disease	0,75	disease	0,68	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,15	high_impact	2,98	0,48	0,8	68,72	19,58	P	0,82	P	0,97	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8058	8058	A	C	MI.6201	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	473	158	D	A	gAc/gCc	5,13	1	0	probably_damaging	1	neutral	0,73	neutral	0,42	deleterious	-7,15	deleterious	-7,86	high_impact	4,01	damaging	0,22	damaging	0,08	deleterious	3,71	23,3	0,18	0,45	disease	0,64	disease	0,78	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	0,44	high_impact	2,65	0,51	0,8	68,72	19,58	P	0,77	P	0,96	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8058	8058	A	T	MI.6202	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	473	158	D	V	gAc/gTc	5,13	1	0	probably_damaging	1	neutral	0,73	neutral	0,4	deleterious	-9,11	deleterious	-8,84	high_impact	4,7	damaging	0,14	damaging	0,01	deleterious	3,8	23,4	0,17	0,45	disease	0,96	disease	0,89	disease	0,78	disease	0,64	3	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	0,44	high_impact	3,3	0,33	0,8	68,72	19,58	P	0,71	P	0,99	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8059	8059	C	G	MI.6203	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	474	158	D	E	gaC/gaG	8,59	1	0	probably_damaging	0,99	neutral	0,61	neutral	0,47	deleterious	-5,37	deleterious	-3,93	high_impact	4,01	damaging	0,16	damaging	0,03	deleterious	3,99	23,6	0,3	0,45	disease	0,82	disease	0,75	disease	0,68	disease	0,64	3	deleterious	0,99	neutral	0,31	deleterious	2	deleterious	0,88	low_impact	-2,58	medium_impact	0,31	high_impact	2,65	0,56	0,8	68,72	19,58	P	0,85	P	0,95	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8059	8059	C	A	MI.6204	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	474	158	D	E	gaC/gaA	8,59	1	0	probably_damaging	0,99	neutral	0,61	neutral	0,47	deleterious	-5,37	deleterious	-3,93	high_impact	4,01	damaging	0,16	damaging	0,03	deleterious	4,36	24,1	0,3	0,45	disease	0,82	disease	0,75	disease	0,68	disease	0,64	3	deleterious	0,99	neutral	0,31	deleterious	2	deleterious	0,88	low_impact	-2,58	medium_impact	0,31	high_impact	2,65	0,56	0,8	68,72	19,58	P	0,86	P	0,95	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8060	8060	G	C	MI.6205	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	475	159	V	L	Gtc/Ctc	-8,7	0	0	probably_damaging	0,99	neutral	0,36	neutral	1,47	deleterious	-4,37	deleterious	-2,95	high_impact	4,74	damaging	0,13	damaging	0,03	deleterious	3,7	23,3	0,24	0,45	disease	0,72	disease	0,7	disease	0,75	disease	0,7	4	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,83	low_impact	-2,58	medium_impact	0,07	high_impact	3,34	0,56	0,8	68,72	19,45	P	0,74	P	0,23	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8060	8060	G	A	MI.6206	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	475	159	V	I	Gtc/Atc	-8,7	0	0	probably_damaging	0,99	neutral	0,28	neutral	1,5	deleterious	-4,28	neutral	-0,98	high_impact	4,18	damaging	0,2	damaging	0,03	deleterious	3,83	23,4	0,34	0,5	disease	0,51	disease	0,63	disease	0,71	disease	0,66	3	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,74	low_impact	-2,58	medium_impact	-0,02	high_impact	2,81	0,8	0,85	68,72	19,45	P	0,7	P	0,3	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8060	8060	G	T	MI.6207	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	475	159	V	F	Gtc/Ttc	-8,7	0	0	probably_damaging	1	deleterious	0,02	neutral	1,35	deleterious	-5,89	deleterious	-4,91	high_impact	4,74	damaging	0,14	damaging	0,02	deleterious	3,94	23,5	0,12	0,4	disease	0,87	disease	0,87	disease	0,79	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-3,52	medium_impact	-0,73	high_impact	3,34	0,47	0,8	68,72	19,45	P	0,74	P	0,94	polymorphism	0,99	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8061	8061	T	C	MI.6208	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	476	159	V	A	gTc/gCc	6,06	1	0	probably_damaging	1	neutral	0,36	neutral	1,37	deleterious	-4,98	deleterious	-3,93	high_impact	4,18	damaging	0,2	damaging	0,1	deleterious	3,66	23,2	0,23	0,45	disease	0,57	disease	0,63	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,79	low_impact	-3,52	medium_impact	0,07	high_impact	2,81	0,35	0,8	68,72	19,45	P	0,89	P	0,59	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8061	8061	T	A	MI.6209	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	476	159	V	D	gTc/gAc	6,06	1	0	probably_damaging	1	neutral	0,37	neutral	1,31	deleterious	-7,75	deleterious	-6,87	high_impact	4,74	damaging	0,22	damaging	0,03	deleterious	4,58	24,4	0,07	0,35	disease	0,95	disease	0,87	disease	0,84	disease	0,68	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,08	high_impact	3,34	0,25	0,8	68,72	19,45	P	0,78	P	0,9	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8819	8819	T	G	MI.621	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	293	98	L	R	cTa/cGa	-0,1	0,62	0	probably_damaging	1	deleterious	0	neutral	4,12	deleterious	-3,9	deleterious	-5,16	high_impact	4,37	damaging	0,35	damaging	0,13	deleterious	4,13	23,8	0,12	0,65	disease	0,69	disease	0,8	disease	0,81	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,6	low_impact	-1,4	high_impact	2,65	0,53	0,9	48,67	8,57	P	0,71	P	0,99	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8061	8061	T	G	MI.6210	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	476	159	V	G	gTc/gGc	6,06	1	0	probably_damaging	1	neutral	0,17	neutral	1,32	deleterious	-6,84	deleterious	-6,87	high_impact	4,18	damaging	0,16	damaging	0,05	deleterious	3,97	23,6	0,11	0,4	disease	0,9	disease	0,79	disease	0,79	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	-0,18	high_impact	2,81	0,29	0,8	68,72	19,45	P	0,85	P	0,84	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8063	8063	T	A	MI.6211	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	478	160	L	M	Ttg/Atg	-20	0	0,01	probably_damaging	1	neutral	0,26	neutral	1,88	neutral	-2,07	neutral	-1,91	medium_impact	2,45	damaging	0,4	damaging	0,05	deleterious	3,63	23,2	0,24	0,45	neutral	0,41	disease	0,58	neutral	0,45	neutral	0,46	1	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,75	low_impact	-3,52	medium_impact	-0,05	medium_impact	1,19	0,64	0,8	70,04	18,81	N	0,37	N	0,78	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8063	8063	T	G	MI.6212	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	478	160	L	V	Ttg/Gtg	-20	0	0,01	probably_damaging	0,99	neutral	0,76	neutral	1,9	neutral	-1,27	deleterious	-2,73	medium_impact	2,48	damaging	0,29	damaging	0,02	deleterious	3,52	23,1	0,21	0,45	neutral	0,42	disease	0,67	disease	0,51	disease	0,51	0	deleterious	0,99	neutral	0,39	deleterious	1	deleterious	0,76	low_impact	-2,58	medium_impact	0,48	medium_impact	1,22	0,55	0,8	70,04	18,81	P	0,5	N	0,66	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8064	8064	T	C	MI.6213	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	479	160	L	S	tTg/tCg	-0,4	0	0	probably_damaging	1	neutral	0,75	neutral	1,84	neutral	-2,63	deleterious	-5,78	medium_impact	3,35	damaging	0,35	damaging	0,02	deleterious	3,88	23,5	0,15	0,4	disease	0,69	disease	0,8	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,85	low_impact	-3,52	medium_impact	0,47	high_impact	2,04	0,48	0,8	70,04	18,81	N	0,38	N	0,94	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8064	8064	T	G	MI.6214	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	479	160	L	W	tTg/tGg	-0,4	0	0	probably_damaging	1	neutral	0,21	neutral	1,8	deleterious	-4,24	deleterious	-5,84	high_impact	3,54	damaging	0,23	damaging	0,01	deleterious	3,91	23,5	0,1	0,4	disease	0,9	disease	0,81	disease	0,64	disease	0,64	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	-0,11	high_impact	2,21	0,4	0,8	70,04	18,81	P	0,73	P	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8065	8065	G	C	MI.6215	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	480	160	L	F	ttG/ttC	7,44	0,96	0,01	probably_damaging	1	neutral	0,66	neutral	1,83	neutral	-2,77	deleterious	-3,82	high_impact	3,54	damaging	0,29	damaging	0,02	deleterious	3,6	23,2	0,24	0,45	disease	0,69	disease	0,72	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	0,36	high_impact	2,21	0,64	0,8	70,04	18,81	P	0,73	P	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8065	8065	G	T	MI.6216	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	480	160	L	F	ttG/ttT	7,44	0,96	0,01	probably_damaging	1	neutral	0,66	neutral	1,83	neutral	-2,77	deleterious	-3,82	high_impact	3,54	damaging	0,29	damaging	0,02	deleterious	3,75	23,3	0,24	0,45	disease	0,69	disease	0,72	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	0,36	high_impact	2,21	0,64	0,8	70,04	18,81	P	0,74	P	0,91	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8066	8066	C	G	MI.6217	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	481	161	H	D	Cac/Gac	-12,39	0	0	probably_damaging	1	neutral	0,22	neutral	1,04	deleterious	-6,55	deleterious	-8,83	high_impact	4,72	damaging	0,34	damaging	0,17	deleterious	4	23,6	0,15	0,4	disease	0,88	disease	0,79	disease	0,88	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	-0,1	high_impact	3,32	0,38	0,8	68,72	19,9	P	0,59	P	0,97	polymorphism	0,93	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8066	8066	C	A	MI.6218	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	481	161	H	N	Cac/Aac	-12,39	0	0	probably_damaging	1	neutral	0,31	neutral	1,1	deleterious	-5,8	deleterious	-6,87	high_impact	4,72	damaging	0,32	damaging	0,18	deleterious	4,01	23,6	0,22	0,45	disease	0,74	disease	0,75	disease	0,83	disease	0,69	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	0,01	high_impact	3,32	0,48	0,8	68,72	19,9	P	0,63	P	0,96	polymorphism	0,98	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8066	8066	C	T	MI.6219	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	481	161	H	Y	Cac/Tac	-12,39	0	0	probably_damaging	0,99	neutral	1	neutral	1,02	deleterious	-7,03	deleterious	-5,89	high_impact	4,72	damaging	0,31	damaging	0,12	deleterious	3,83	23,4	0,2	0,45	disease	0,92	disease	0,8	disease	0,84	disease	0,69	4	deleterious	0,99	deleterious	0,51	deleterious	2	deleterious	0,89	low_impact	-2,58	high_impact	1,86	high_impact	3,32	0,39	0,8	68,72	19,9	P	0,59	P	0,99	polymorphism	0,97	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8819	8819	T	A	MI.622	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	293	98	L	Q	cTa/cAa	-0,1	0,62	0	probably_damaging	1	deleterious	0	neutral	4,12	deleterious	-3,95	deleterious	-5,16	high_impact	4,37	damaging	0,43	damaging	0,14	deleterious	4,24	23,9	0,16	0,65	disease	0,88	disease	0,73	disease	0,71	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,6	low_impact	-1,4	high_impact	2,65	0,72	0,9	48,67	8,57	P	0,51	P	0,98	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8067	8067	A	G	MI.6220	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	482	161	H	R	cAc/cGc	5,6	1	0	probably_damaging	1	neutral	0,34	neutral	1,05	deleterious	-6,36	deleterious	-7,85	high_impact	4,72	damaging	0,32	damaging	0,15	deleterious	3,14	22,6	0,22	0,45	disease	0,87	disease	0,82	disease	0,86	disease	0,65	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	0,05	high_impact	3,32	0,37	0,8	68,72	19,9	P	0,79	P	0,95	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8067	8067	A	T	MI.6221	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	482	161	H	L	cAc/cTc	5,6	1	0	probably_damaging	1	neutral	0,65	neutral	1,03	deleterious	-6,85	deleterious	-10,8	high_impact	4,72	damaging	0,28	neutral	0,31	deleterious	4	23,6	0,13	0,4	disease	0,59	disease	0,84	disease	0,84	disease	0,72	4	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	0,35	high_impact	3,32	0,42	0,8	68,72	19,9	P	0,83	P	0,91	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8067	8067	A	C	MI.6222	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	482	161	H	P	cAc/cCc	5,6	1	0	probably_damaging	1	neutral	0,21	neutral	1,02	deleterious	-7,93	deleterious	-9,81	high_impact	4,38	damaging	0,3	damaging	0,18	deleterious	3,4	23	0,13	0,4	disease	0,93	disease	0,83	disease	0,83	disease	0,66	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	-0,11	high_impact	3	0,34	0,8	68,72	19,9	P	0,75	P	0,98	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8068	8068	C	G	MI.6223	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	483	161	H	Q	caC/caG	6,98	1	0	probably_damaging	1	neutral	0,29	neutral	1,04	deleterious	-6,75	deleterious	-7,85	high_impact	4,72	damaging	0,32	damaging	0,2	deleterious	3,71	23,3	0,23	0,45	disease	0,88	disease	0,75	disease	0,84	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,01	high_impact	3,32	0,49	0,8	68,72	19,9	P	0,8	P	0,94	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8068	8068	C	A	MI.6224	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	483	161	H	Q	caC/caA	6,98	1	0	probably_damaging	1	neutral	0,29	neutral	1,04	deleterious	-6,75	deleterious	-7,85	high_impact	4,72	damaging	0,32	damaging	0,2	deleterious	3,94	23,5	0,23	0,45	disease	0,88	disease	0,75	disease	0,84	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,01	high_impact	3,32	0,49	0,8	68,72	19,9	P	0,81	P	0,94	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8069	8069	T	C	MI.6225	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	484	162	S	P	Tca/Cca	0,75	1	0	probably_damaging	1	neutral	0,32	neutral	1,44	deleterious	-4,47	deleterious	-4,88	high_impact	3,99	damaging	0,41	neutral	0,35	deleterious	4,17	23,8	0,16	0,45	disease	0,91	disease	0,8	disease	0,71	disease	0,65	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	0,02	high_impact	2,64	0,71	0,85	66,96	19,91	P	0,65	P	0,83	disease_causing	0,84	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8069	8069	T	A	MI.6226	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	484	162	S	T	Tca/Aca	0,75	1	0	probably_damaging	0,97	neutral	0,69	neutral	1,46	deleterious	-3,83	deleterious	-2,93	high_impact	3,85	damaging	0,33	neutral	0,39	deleterious	4,06	23,7	0,18	0,45	disease	0,79	disease	0,65	disease	0,72	disease	0,66	3	neutral	0,97	neutral	0,36	deleterious	2	deleterious	0,84	low_impact	-2,13	medium_impact	0,4	high_impact	2,5	0,8	0,85	66,96	19,91	P	0,68	P	0,62	polymorphism	0,55	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8069	8069	T	G	MI.6227	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	484	162	S	A	Tca/Gca	0,75	1	0	probably_damaging	0,99	neutral	0,9	neutral	1,59	neutral	-1,89	deleterious	-2,9	medium_impact	2,07	damaging	0,56	neutral	0,81	deleterious	2,75	21,1	0,23	0,45	neutral	0,48	disease	0,52	disease	0,51	neutral	0,17	7	deleterious	0,98	neutral	0,46	deleterious	1	deleterious	0,75	low_impact	-2,58	medium_impact	0,73	medium_impact	0,84	0,83	0,85	66,96	19,91	N	0,4	N	0,15	polymorphism	0,8	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8070	8070	C	G	MI.6228	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	485	162	S	W	tCa/tGa	5,83	1	0	probably_damaging	1	neutral	0,14	neutral	1,41	deleterious	-7,35	deleterious	-6,85	high_impact	4,54	damaging	0,32	neutral	0,36	deleterious	4,5	24,3	0,09	0,35	disease	0,97	disease	0,87	disease	0,76	disease	0,64	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,23	high_impact	3,15	0,44	0,8	66,96	19,91	P	0,73	P	0,99	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8070	8070	C	T	MI.6229	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	485	162	S	L	tCa/tTa	5,83	1	0	probably_damaging	1	neutral	0,55	neutral	1,43	deleterious	-5,33	deleterious	-5,86	high_impact	3,85	damaging	0,31	neutral	0,36	deleterious	4,83	24,8	0,11	0,4	disease	0,58	disease	0,81	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	0,25	high_impact	2,5	0,82	0,85	66,96	19,91	P	0,76	P	0,94	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8819	8819	T	C	MI.623	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	293	98	L	P	cTa/cCa	-0,1	0,62	0	probably_damaging	1	neutral	0,13	neutral	4,18	deleterious	-3,8	deleterious	-6,06	medium_impact	3,17	damaging	0,46	damaging	0,17	deleterious	3,97	23,6	0,13	0,65	disease	0,74	disease	0,71	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	-0,18	medium_impact	1,62	0,57	0,9	48,67	8,57	N	0,4	N	1	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8072	8072	T	C	MI.6230	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	487	163	W	R	Tga/Cga	-0,86	0,03	0	probably_damaging	1	neutral	0,58	neutral	1,61	deleterious	-5,05	deleterious	-13,75	high_impact	4,49	damaging	0,19	damaging	0,01	deleterious	3,68	23,3	0,23	0,45	neutral	0,41	disease	0,88	disease	0,83	disease	0,74	5	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	0,28	high_impact	3,1	0,2	0,8	68,72	19,55	P	0,58	P	0,96	disease_causing	0,96	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8072	8072	T	G	MI.6231	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	487	163	W	G	Tga/Gga	-0,86	0,03	0	probably_damaging	1	neutral	0,45	neutral	1,61	deleterious	-5,28	deleterious	-12,76	high_impact	4,14	damaging	0,16	damaging	0,01	deleterious	4,05	23,7	0,19	0,45	disease	0,81	disease	0,83	disease	0,8	disease	0,69	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	0,16	high_impact	2,78	0,23	0,8	68,72	19,55	P	0,63	P	0,98	disease_causing	0,98	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8073	8073	G	C	MI.6232	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	488	163	W	S	tGa/tCa	7,44	1	0	probably_damaging	1	neutral	0,79	neutral	1,62	deleterious	-4,38	deleterious	-13,74	high_impact	3,94	damaging	0,14	damaging	0,01	deleterious	4,16	23,8	0,19	0,45	disease	0,7	disease	0,9	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,4	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,52	high_impact	2,59	0,19	0,8	68,72	19,55	P	0,69	P	0,97	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8073	8073	G	T	MI.6233	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	488	163	W	L	tGa/tTa	7,44	1	0	probably_damaging	1	neutral	0,45	neutral	1,67	neutral	-2,65	deleterious	-12,76	high_impact	3,59	damaging	0,2	damaging	0,02	deleterious	4,37	24,1	0,18	0,45	neutral	0,27	disease	0,81	disease	0,78	disease	0,68	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,77	low_impact	-3,52	medium_impact	0,16	high_impact	2,26	0,24	0,8	68,72	19,55	P	0,74	P	0,98	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8074	8074	A	T	MI.6234	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	489	163	W	C	tgA/tgT	9,29	1	0	probably_damaging	1	neutral	0,1	neutral	1,61	deleterious	-5,89	deleterious	-12,76	high_impact	4,49	damaging	0,16	damaging	0,01	deleterious	4,25	23,9	0,22	0,45	disease	0,85	disease	0,88	disease	0,81	disease	0,66	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,32	high_impact	3,1	0,26	0,8	68,72	19,55	P	0,77	P	0,94	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8074	8074	A	C	MI.6235	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	489	163	W	C	tgA/tgC	9,29	1	0	probably_damaging	1	neutral	0,1	neutral	1,61	deleterious	-5,89	deleterious	-12,76	high_impact	4,49	damaging	0,16	damaging	0,01	deleterious	4,17	23,8	0,22	0,45	disease	0,85	disease	0,88	disease	0,81	disease	0,66	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,32	high_impact	3,1	0,26	0,8	68,72	19,55	P	0,76	P	0,94	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8075	8075	G	C	MI.6236	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	490	164	A	P	Gct/Cct	2,37	1	0	probably_damaging	0,91	neutral	0,26	neutral	1,85	deleterious	-3,53	deleterious	-4,46	high_impact	4,03	damaging	0,35	neutral	0,3	deleterious	3,92	23,5	0,11	0,4	disease	0,87	disease	0,83	disease	0,65	disease	0,66	3	neutral	0,93	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-1,66	medium_impact	-0,05	high_impact	2,67	0,83	0,9	27,75	50,21	P	0,67	P	0,83	disease_causing	0,86	0,18	rs386829024	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8075	8075	G	A	MI.6237	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	490	164	A	T	Gct/Act	2,37	1	0	benign	0	neutral	0,52	neutral	2,02	neutral	-1,5	deleterious	-2,93	neutral_impact	0,48	neutral	0,76	neutral	0,86	deleterious	0,64	8,41	0,46	0,55	disease	0,68	neutral	0,06	neutral	0,21	neutral	0,41	2	neutral	0,47	deleterious	0,76	neutral	-6	neutral	0,19	high_impact	2,08	medium_impact	0,22	medium_impact	-0,66	0,73	0,85	27,75	50,21	N	0,47	N	0	disease_causing	0,63	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8075	8075	G	T	MI.6238	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	490	164	A	S	Gct/Tct	2,37	1	0	benign	0,19	neutral	0,52	neutral	1,9	neutral	-1,6	neutral	-2,5	medium_impact	2,08	damaging	0,47	neutral	0,43	deleterious	2,01	16,25	0,42	0,55	disease	0,73	disease	0,59	neutral	0,49	neutral	0,36	3	neutral	0,38	deleterious	0,67	neutral	-3	neutral	0,32	medium_impact	-0,13	medium_impact	0,22	medium_impact	0,85	0,86	0,9	27,75	50,21	N	0,5	N	0,47	polymorphism	0,57	0,04	rs386829024	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8076	8076	C	T	MI.6239	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	491	164	A	V	gCt/gTt	4,21	1	0	benign	0,12	neutral	0,58	neutral	1,91	neutral	-1,21	deleterious	-3,48	medium_impact	3,34	damaging	0,45	neutral	0,33	deleterious	2,59	20,1	0,31	0,5	disease	0,64	disease	0,61	disease	0,68	disease	0,69	4	neutral	0,32	deleterious	0,73	neutral	-3	deleterious	0,45	medium_impact	0,09	medium_impact	0,28	high_impact	2,03	0,75	0,85	27,75	50,21	P	0,62	P	0,48	disease_causing	0,62	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8821	8821	T	C	MI.624	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	295	99	S	P	Tct/Cct	-2,42	0	0	probably_damaging	0,99	neutral	0,1	neutral	3,78	deleterious	-3,23	deleterious	-4,37	high_impact	4,12	damaging	0,42	neutral	0,57	deleterious	3,9	23,5	0,18	0,65	disease	0,8	disease	0,82	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-2,65	medium_impact	-0,25	high_impact	2,43	0,71	0,9	43,36	8,06	P	0,6	P	0,99	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8076	8076	C	G	MI.6240	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	491	164	A	G	gCt/gGt	4,21	1	0	benign	0,08	neutral	0,37	neutral	1,89	neutral	-1,6	deleterious	-3,7	medium_impact	2,75	damaging	0,46	neutral	0,47	deleterious	2,17	17,32	0,33	0,5	disease	0,87	disease	0,59	disease	0,64	disease	0,66	3	neutral	0,59	deleterious	0,65	neutral	-3	neutral	0,33	medium_impact	0,27	medium_impact	0,08	medium_impact	1,47	0,81	0,85	27,75	50,21	P	0,54	P	0,54	disease_causing	0,57	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8076	8076	C	A	MI.6241	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	491	164	A	D	gCt/gAt	4,21	1	0	possibly_damaging	0,81	neutral	0,3	neutral	1,84	deleterious	-3,37	deleterious	-5,33	high_impact	3,68	damaging	0,49	neutral	0,31	deleterious	4,48	24,2	0,17	0,45	disease	0,92	disease	0,83	disease	0,75	disease	0,65	3	neutral	0,84	neutral	0,25	deleterious	1	deleterious	0,7	low_impact	-1,31	medium_impact	0	high_impact	2,35	0,61	0,8	27,75	50,21	P	0,57	P	0,95	disease_causing	0,88	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8078	8078	G	T	MI.6242	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	493	165	V	F	Gtc/Ttc	-16,08	0	0	possibly_damaging	0,5	neutral	0,75	neutral	1,42	deleterious	-5,25	deleterious	-4,21	high_impact	3,7	damaging	0,47	neutral	0,41	deleterious	3,61	23,2	0,17	0,45	disease	0,93	disease	0,82	disease	0,71	disease	0,66	3	neutral	0,4	deleterious	0,63	deleterious	1	deleterious	0,57	medium_impact	-0,72	medium_impact	0,47	high_impact	2,36	0,58	0,8	28,19	35,21	N	0,29	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8078	8078	G	A	MI.6243	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	493	165	V	I	Gtc/Atc	-16,08	0	0	benign	0	neutral	0,48	neutral	1,98	neutral	-0,06	neutral	-0,36	neutral_impact	0,52	neutral	0,89	neutral	0,95	deleterious	0,12	3,83	0,51	0,6	neutral	0,34	neutral	0,06	neutral	0,23	neutral	0,24	5	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,14	high_impact	2,08	medium_impact	0,19	medium_impact	-0,62	0,97	1	28,19	35,21	N	0,55	P	0,06	polymorphism	1	0	rs878993263	.	.	.	.	.	.	.	.	G8078A	DEAF	+	-	Reported	2
chrM	8078	8078	G	C	MI.6244	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	493	165	V	L	Gtc/Ctc	-16,08	0	0	benign	0,01	neutral	0,76	neutral	1,6	neutral	-1,79	neutral	-2,2	low_impact	1,08	damaging	0,57	neutral	0,54	deleterious	0,75	9,12	0,37	0,5	disease	0,51	disease	0,52	neutral	0,39	neutral	0,19	6	neutral	0,21	deleterious	0,88	neutral	-6	neutral	0,24	medium_impact	1,14	medium_impact	0,48	medium_impact	-0,09	0,74	0,85	28,19	35,21	N	0,27	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8079	8079	T	A	MI.6245	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	494	165	V	D	gTc/gAc	0,29	0,05	0	possibly_damaging	0,74	neutral	0,21	neutral	1,4	deleterious	-7,83	deleterious	-6,5	high_impact	4,05	damaging	0,48	neutral	0,34	deleterious	4,4	24,1	0,09	0,4	disease	0,98	disease	0,85	disease	0,79	disease	0,76	5	neutral	0,85	neutral	0,24	deleterious	1	deleterious	0,79	low_impact	-1,14	medium_impact	-0,11	high_impact	2,69	0,54	0,8	28,19	35,21	N	0,44	N	0,98	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8079	8079	T	C	MI.6246	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	494	165	V	A	gTc/gCc	0,29	0,05	0	benign	0,34	neutral	0,58	neutral	1,49	deleterious	-3,02	deleterious	-3,86	medium_impact	2,9	damaging	0,53	neutral	0,56	deleterious	2,05	16,54	0,3	0,45	disease	0,89	disease	0,51	disease	0,68	disease	0,7	4	neutral	0,34	deleterious	0,62	neutral	-3	neutral	0,42	medium_impact	-0,45	medium_impact	0,28	medium_impact	1,61	0,54	0,8	28,19	35,21	N	0,3	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8079	8079	T	G	MI.6247	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	494	165	V	G	gTc/gGc	0,29	0,05	0	possibly_damaging	0,79	neutral	0,33	neutral	1,41	deleterious	-6,59	deleterious	-6,79	high_impact	4,05	damaging	0,51	neutral	0,51	deleterious	3,8	23,4	0,16	0,45	disease	0,98	disease	0,73	disease	0,71	disease	0,72	4	neutral	0,82	neutral	0,27	deleterious	1	deleterious	0,73	low_impact	-1,26	medium_impact	0,04	high_impact	2,69	0,48	0,8	28,19	35,21	N	0,35	N	0,94	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8081	8081	C	G	MI.6248	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	496	166	P	A	Ccc/Gcc	-15,39	0	0	probably_damaging	1	neutral	0,56	neutral	1,37	deleterious	-3,64	deleterious	-7,58	high_impact	3,81	damaging	0,15	damaging	0,11	deleterious	3,22	22,7	0,19	0,45	disease	0,77	disease	0,69	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	0,26	high_impact	2,47	0,59	0,8	68,72	19,6	P	0,53	P	0,9	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8081	8081	C	A	MI.6249	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	496	166	P	T	Ccc/Acc	-15,39	0	0	probably_damaging	1	neutral	0,54	neutral	1,36	deleterious	-4,04	deleterious	-7,58	high_impact	4,15	damaging	0,1	damaging	0,02	deleterious	3,82	23,4	0,22	0,45	disease	0,81	disease	0,8	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,24	high_impact	2,79	0,62	0,8	68,72	19,6	P	0,47	N	0,96	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8821	8821	T	G	MI.625	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	295	99	S	A	Tct/Gct	-2,42	0	0	probably_damaging	0,97	neutral	0,34	neutral	3,88	neutral	0,26	deleterious	-2,51	low_impact	1,9	neutral	0,72	neutral	0,62	deleterious	3,59	23,2	0,44	0,65	neutral	0,35	neutral	0,37	disease	0,53	neutral	0,43	1	neutral	0,97	neutral	0,19	neutral	-2	deleterious	0,68	low_impact	-2,19	medium_impact	0,13	medium_impact	0,53	0,81	0,9	43,36	8,06	N	0,37	N	0,45	disease_causing	0,98	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8081	8081	C	T	MI.6250	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	496	166	P	S	Ccc/Tcc	-15,39	0	0	probably_damaging	1	neutral	0,5	neutral	1,37	deleterious	-3,98	deleterious	-7,54	medium_impact	3,46	damaging	0,11	damaging	0,03	deleterious	4,04	23,7	0,31	0,5	disease	0,82	disease	0,83	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,88	low_impact	-3,52	medium_impact	0,21	high_impact	2,14	0,24	0,8	68,72	19,6	P	0,54	P	0,94	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8082	8082	C	T	MI.6251	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	497	166	P	L	cCc/cTc	7,21	1	0	probably_damaging	1	neutral	0,78	neutral	1,38	deleterious	-3,88	deleterious	-9,48	high_impact	4,7	damaging	0,08	damaging	0,02	deleterious	4,56	24,4	0,25	0,45	disease	0,64	disease	0,86	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	0,51	high_impact	3,3	0,87	0,9	68,72	19,6	P	0,74	P	0,92	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8082	8082	C	A	MI.6252	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	497	166	P	H	cCc/cAc	7,21	1	0	probably_damaging	1	neutral	0,56	neutral	1,32	deleterious	-5,54	deleterious	-8,59	high_impact	4,7	damaging	0,08	damaging	0,02	deleterious	4,18	23,8	0,18	0,45	disease	0,92	disease	0,86	disease	0,8	disease	0,64	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,26	high_impact	3,3	0,56	0,8	68,72	19,6	P	0,8	P	0,79	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8082	8082	C	G	MI.6253	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	497	166	P	R	cCc/cGc	7,21	1	0	probably_damaging	1	neutral	0,35	neutral	1,34	deleterious	-4,57	deleterious	-8,58	high_impact	4,35	damaging	0,12	damaging	0,02	deleterious	3,74	23,3	0,16	0,45	disease	0,88	disease	0,89	disease	0,82	disease	0,64	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	0,06	high_impact	2,97	0,51	0,8	68,72	19,6	P	0,83	P	0,85	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8084	8084	A	T	MI.6254	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	499	167	T	S	Aca/Tca	-11,7	0	0	benign	0	neutral	0,47	neutral	2,23	neutral	2,25	neutral	0,88	neutral_impact	-2,54	neutral	0,85	neutral	0,99	neutral	-1,09	0,01	0,55	0,6	neutral	0,49	neutral	0,05	neutral	0,12	neutral	0,23	6	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,13	high_impact	2,08	medium_impact	0,18	low_impact	-3,49	0,64	0,8	29,07	54,15	N	0,5	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8084	8084	A	G	MI.6255	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	499	167	T	A	Aca/Gca	-11,7	0	0	benign	0	neutral	0,55	neutral	2,1	neutral	1,37	neutral	0,22	neutral_impact	-1,3	neutral	0,78	neutral	0,9	neutral	-0,26	0,83	0,64	0,7	neutral	0,44	neutral	0,15	neutral	0,19	neutral	0,31	4	neutral	0,44	deleterious	0,78	neutral	-6	neutral	0,15	high_impact	2,08	medium_impact	0,25	low_impact	-2,32	0,46	0,8	29,07	54,15	N	0,46	N	0,2	polymorphism	1	0	rs1057518824	Uncertain significance|Uncertain significance	Focal_white_matter_lesions|Ischemic_stroke	RCV000414851.1|RCV000414851.1	Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen	.	.	.	.	.	.	.	.	.	.
chrM	8084	8084	A	C	MI.6256	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	499	167	T	P	Aca/Cca	-11,7	0	0	benign	0,38	neutral	0,23	neutral	1,99	neutral	-0,25	neutral	-2,24	low_impact	1,21	neutral	0,63	neutral	0,44	deleterious	2,02	16,35	0,22	0,45	neutral	0,34	disease	0,81	neutral	0,32	disease	0,62	2	neutral	0,73	neutral	0,43	neutral	-6	neutral	0,39	medium_impact	-0,52	medium_impact	-0,09	medium_impact	0,03	0,42	0,8	29,07	54,15	N	0,39	N	0,52	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8085	8085	C	A	MI.6257	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	500	167	T	K	aCa/aAa	-0,17	0	0	benign	0,15	neutral	0,29	neutral	2,03	neutral	0,53	neutral	-1,93	neutral_impact	0,38	neutral	0,63	neutral	0,55	deleterious	2,84	21,6	0,33	0,5	neutral	0,28	disease	0,67	disease	0,53	disease	0,57	1	neutral	0,66	deleterious	0,57	neutral	-6	neutral	0,27	medium_impact	-0,02	medium_impact	-0,01	medium_impact	-0,75	0,73	0,85	29,07	54,15	N	0,38	N	0,42	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8085	8085	C	T	MI.6258	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	500	167	T	M	aCa/aTa	-0,17	0	0	possibly_damaging	0,73	neutral	0,23	neutral	1,94	neutral	-2,89	neutral	-2,41	neutral_impact	0,79	neutral	0,71	neutral	0,55	deleterious	4	23,6	0,36	0,5	disease	0,67	disease	0,53	neutral	0,38	neutral	0,45	1	neutral	0,83	neutral	0,25	neutral	-3	deleterious	0,58	low_impact	-1,12	medium_impact	-0,09	medium_impact	-0,37	0,63	0,8	29,07	54,15	N	0,34	N	0,6	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8087	8087	T	A	MI.6259	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	502	168	L	M	Tta/Ata	-5,47	0	0	probably_damaging	1	neutral	0,16	neutral	1,66	neutral	-2,41	neutral	-1,45	low_impact	1,5	damaging	0,53	neutral	0,44	deleterious	2,6	20,2	0,38	0,5	disease	0,84	neutral	0,31	neutral	0,32	disease	0,62	2	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,78	low_impact	-3,52	medium_impact	-0,19	medium_impact	0,3	0,73	0,85	68,72	19,34	N	0,4	N	0,78	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8821	8821	T	A	MI.626	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	295	99	S	T	Tct/Act	-2,42	0	0	probably_damaging	0,98	neutral	0,28	neutral	3,85	neutral	-0,9	neutral	-2,37	medium_impact	2,6	neutral	0,81	neutral	0,61	deleterious	3,73	23,3	0,36	0,65	disease	0,53	disease	0,5	disease	0,54	neutral	0,37	3	deleterious	0,98	neutral	0,15	deleterious	1	deleterious	0,73	low_impact	-2,36	medium_impact	0,06	medium_impact	1,13	0,91	0,95	43,36	8,06	N	0,32	N	0,67	disease_causing	0,99	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8087	8087	T	G	MI.6260	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	502	168	L	V	Tta/Gta	-5,47	0	0	probably_damaging	0,98	neutral	0,38	neutral	1,68	neutral	-1,94	deleterious	-2,71	medium_impact	3,3	damaging	0,33	damaging	0,04	deleterious	3,55	23,1	0,39	0,5	disease	0,6	disease	0,58	disease	0,67	disease	0,55	1	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,79	low_impact	-2,3	medium_impact	0,09	medium_impact	1,99	0,54	0,8	68,72	19,34	N	0,48	N	0,66	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8088	8088	T	C	MI.6261	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	503	168	L	S	tTa/tCa	-1,32	0	0	probably_damaging	1	neutral	0,79	neutral	1,64	deleterious	-3,31	deleterious	-5,42	medium_impact	3,19	damaging	0,31	damaging	0,05	deleterious	3,94	23,5	0,24	0,45	disease	0,83	disease	0,75	disease	0,66	disease	0,6	2	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,87	low_impact	-3,52	medium_impact	0,52	medium_impact	1,89	0,61	0,8	68,72	19,34	N	0,44	N	0,94	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8088	8088	T	G	MI.6262	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	503	168	L	W	tTa/tGa	-1,32	0	0	probably_damaging	1	deleterious	0,04	neutral	1,61	deleterious	-4,99	deleterious	-5,44	high_impact	3,79	damaging	0,31	damaging	0,02	deleterious	3,93	23,5	0,22	0,45	disease	0,96	disease	0,74	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,87	low_impact	-3,52	medium_impact	-0,56	high_impact	2,45	0,51	0,8	68,72	19,34	P	0,51	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8089	8089	A	C	MI.6263	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	504	168	L	F	ttA/ttC	5,6	0,88	0	probably_damaging	1	neutral	0,09	neutral	1,77	neutral	-0,12	deleterious	-3,54	low_impact	1,62	damaging	0,45	damaging	0,03	deleterious	3,61	23,2	0,36	0,5	neutral	0,37	disease	0,67	disease	0,53	neutral	0,46	1	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,76	low_impact	-3,52	medium_impact	-0,35	medium_impact	0,41	0,63	0,8	68,72	19,34	N	0,45	N	0,91	polymorphism	0,73	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8089	8089	A	T	MI.6264	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	504	168	L	F	ttA/ttT	5,6	0,88	0	probably_damaging	1	neutral	0,09	neutral	1,77	neutral	-0,12	deleterious	-3,54	low_impact	1,62	damaging	0,45	damaging	0,03	deleterious	3,69	23,3	0,36	0,5	neutral	0,37	disease	0,67	disease	0,53	neutral	0,46	1	deleterious	1	neutral	0,05	neutral	-2	deleterious	0,76	low_impact	-3,52	medium_impact	-0,35	medium_impact	0,41	0,63	0,8	68,72	19,34	N	0,46	N	0,91	polymorphism	0,73	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8090	8090	G	C	MI.6265	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	505	169	G	R	Ggc/Cgc	-5,47	0	0	probably_damaging	0,97	neutral	0,36	neutral	1,65	neutral	-2,19	deleterious	-7,58	high_impact	3,9	damaging	0,29	damaging	0,1	deleterious	4,06	23,7	0,36	0,5	neutral	0,38	disease	0,86	disease	0,78	disease	0,69	4	neutral	0,97	neutral	0,2	deleterious	2	deleterious	0,82	low_impact	-2,13	medium_impact	0,07	high_impact	2,55	0,91	0,95	67,4	19,84	P	0,63	P	1	disease_causing	0,7	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8090	8090	G	A	MI.6266	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	505	169	G	S	Ggc/Agc	-5,47	0	0	possibly_damaging	0,72	neutral	0,41	neutral	1,63	neutral	-2,54	deleterious	-5,66	medium_impact	2,69	damaging	0,29	damaging	0,16	deleterious	4,16	23,8	0,38	0,5	disease	0,64	disease	0,74	disease	0,63	neutral	0,35	3	neutral	0,73	neutral	0,35	NA	0	deleterious	0,71	low_impact	-1,1	medium_impact	0,12	medium_impact	1,42	0,77	0,85	67,4	19,84	P	0,7	P	0,98	disease_causing	0,52	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8090	8090	G	T	MI.6267	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	505	169	G	C	Ggc/Tgc	-5,47	0	0	probably_damaging	0,98	neutral	0,18	neutral	1,55	deleterious	-5,82	deleterious	-8,59	medium_impact	3,21	damaging	0,28	damaging	0,12	deleterious	4,32	24	0,24	0,45	disease	0,94	disease	0,87	disease	0,73	disease	0,61	2	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,89	low_impact	-2,3	medium_impact	-0,16	medium_impact	1,9	0,61	0,8	67,4	19,84	P	0,67	P	0,99	disease_causing	0,82	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8091	8091	G	T	MI.6268	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	506	169	G	V	gGc/gTc	7,44	1	0	probably_damaging	0,97	neutral	0,52	neutral	1,57	deleterious	-4,23	deleterious	-8,59	high_impact	3,9	damaging	0,29	damaging	0,13	deleterious	3,86	23,5	0,25	0,45	disease	0,79	disease	0,86	disease	0,75	disease	0,67	3	neutral	0,97	neutral	0,28	deleterious	2	deleterious	0,87	low_impact	-2,13	medium_impact	0,22	high_impact	2,55	0,55	0,8	67,4	19,84	P	0,78	P	1	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8091	8091	G	A	MI.6269	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	506	169	G	D	gGc/gAc	7,44	1	0	benign	0,07	neutral	0,22	neutral	1,63	neutral	-2,48	deleterious	-6,7	high_impact	4,46	damaging	0,35	damaging	0,11	deleterious	2,11	16,93	0,28	0,45	disease	0,77	disease	0,87	disease	0,76	disease	0,68	4	neutral	0,76	deleterious	0,58	neutral	-2	neutral	0,37	medium_impact	0,33	medium_impact	-0,1	high_impact	3,08	0,53	0,8	67,4	19,84	P	0,71	P	0,99	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8822	8822	C	G	MI.627	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	296	99	S	C	tCt/tGt	3,83	0,99	0	probably_damaging	1	neutral	0,08	neutral	3,77	deleterious	-4,35	deleterious	-4,31	medium_impact	3,08	damaging	0,59	neutral	0,46	deleterious	3,46	23	0,24	0,65	disease	0,88	disease	0,74	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	-0,31	medium_impact	1,54	0,8	0,9	43,36	8,06	N	0,45	N	0,99	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8091	8091	G	C	MI.6270	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	506	169	G	A	gGc/gCc	7,44	1	0	possibly_damaging	0,56	neutral	0,51	neutral	1,64	neutral	-2,31	deleterious	-5,64	low_impact	1,71	damaging	0,35	neutral	0,32	deleterious	2,89	21,8	0,5	0,6	disease	0,57	disease	0,65	disease	0,61	neutral	0,37	3	neutral	0,54	deleterious	0,48	neutral	-3	deleterious	0,67	medium_impact	-0,82	medium_impact	0,21	medium_impact	0,5	0,74	0,85	67,4	19,84	P	0,71	P	0,85	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8093	8093	T	A	MI.6271	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	508	170	L	M	Tta/Ata	-12,85	0	0,01	probably_damaging	1	neutral	0,2	neutral	1,87	neutral	-2,1	neutral	-0,41	low_impact	1,09	damaging	0,57	neutral	0,31	deleterious	3,72	23,3	0,3	0,45	disease	0,6	neutral	0,36	neutral	0,18	disease	0,61	2	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,73	low_impact	-3,52	medium_impact	-0,13	medium_impact	-0,08	0,8	0,85	55,07	18,46	N	0,47	N	0,78	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8093	8093	T	G	MI.6272	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	508	170	L	V	Tta/Gta	-12,85	0	0,01	probably_damaging	0,99	neutral	0,66	neutral	2,39	neutral	1,9	neutral	1,28	neutral_impact	-0,86	neutral	0,7	neutral	0,68	deleterious	0,88	9,95	0,35	0,5	neutral	0,35	neutral	0,03	neutral	0,14	neutral	0,22	6	deleterious	0,99	neutral	0,34	neutral	-2	deleterious	0,65	low_impact	-2,58	medium_impact	0,36	low_impact	-1,91	0,57	0,8	55,07	18,46	N	0,45	N	0,66	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8094	8094	T	G	MI.6273	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	509	170	L	W	tTa/tGa	-3,86	0	0	probably_damaging	1	deleterious	0,02	neutral	1,84	deleterious	-4,99	deleterious	-4,25	medium_impact	2,03	damaging	0,4	damaging	0,17	deleterious	3,91	23,5	0,21	0,45	disease	0,9	disease	0,7	disease	0,56	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,85	low_impact	-3,52	medium_impact	-0,73	medium_impact	0,8	0,55	0,8	55,07	18,46	N	0,44	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8094	8094	T	C	MI.6274	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	509	170	L	S	tTa/tCa	-3,86	0	0	probably_damaging	1	neutral	0,71	neutral	1,86	neutral	-2,53	deleterious	-3,36	medium_impact	2,46	damaging	0,47	damaging	0,16	deleterious	3,92	23,5	0,26	0,45	disease	0,69	disease	0,58	disease	0,55	disease	0,66	3	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,81	low_impact	-3,52	medium_impact	0,42	medium_impact	1,2	0,52	0,8	55,07	18,46	N	0,26	N	0,94	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8095	8095	A	C	MI.6275	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	510	170	L	F	ttA/ttC	4,67	0,7	0	probably_damaging	1	neutral	0,05	neutral	1,87	neutral	-2,34	neutral	-2,26	low_impact	1,5	damaging	0,39	damaging	0,15	deleterious	3,62	23,2	0,34	0,5	disease	0,69	disease	0,56	disease	0,53	disease	0,6	2	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,8	low_impact	-3,52	medium_impact	-0,5	medium_impact	0,3	0,59	0,8	55,07	18,46	P	0,64	P	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8095	8095	A	T	MI.6276	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	510	170	L	F	ttA/ttT	4,67	0,7	0	probably_damaging	1	neutral	0,05	neutral	1,87	neutral	-2,34	neutral	-2,26	low_impact	1,5	damaging	0,39	damaging	0,15	deleterious	3,78	23,4	0,34	0,5	disease	0,69	disease	0,56	disease	0,53	disease	0,6	2	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,8	low_impact	-3,52	medium_impact	-0,5	medium_impact	0,3	0,59	0,8	55,07	18,46	P	0,64	P	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8096	8096	A	C	MI.6277	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	511	171	K	Q	Aaa/Caa	-2,01	0	0	probably_damaging	1	neutral	0,54	neutral	1,58	neutral	-2,83	deleterious	-3,93	high_impact	3,6	damaging	0,11	damaging	0,07	deleterious	3,57	23,2	0,38	0,5	disease	0,7	disease	0,81	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	0,24	high_impact	2,27	0,72	0,85	68,72	19,76	P	0,83	P	0,9	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8096	8096	A	G	MI.6278	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	511	171	K	E	Aaa/Gaa	-2,01	0	0	probably_damaging	1	neutral	0,9	neutral	1,54	deleterious	-3,76	deleterious	-3,93	high_impact	4,14	damaging	0,11	damaging	0,05	deleterious	4,14	23,8	0,34	0,5	disease	0,85	disease	0,85	disease	0,76	disease	0,64	3	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,73	high_impact	2,78	0,73	0,85	68,72	19,76	P	0,73	P	0,95	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8097	8097	A	C	MI.6279	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	512	171	K	T	aAa/aCa	8,59	1	0	probably_damaging	1	neutral	0,57	neutral	1,48	deleterious	-4,2	deleterious	-5,88	high_impact	4,14	damaging	0,13	damaging	0,04	deleterious	3,59	23,2	0,24	0,45	disease	0,61	disease	0,81	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	0,27	high_impact	2,78	0,47	0,8	68,72	19,76	P	0,86	P	0,88	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8822	8822	C	A	MI.628	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	296	99	S	Y	tCt/tAt	3,83	0,99	0	probably_damaging	1	neutral	0,47	neutral	3,8	neutral	-2,95	deleterious	-5,16	high_impact	4,12	neutral	0,6	neutral	0,45	deleterious	4,05	23,7	0,2	0,65	disease	0,79	disease	0,79	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	0,26	high_impact	2,43	0,77	0,9	43,36	8,06	N	0,48	N	1	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8097	8097	A	T	MI.6280	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	512	171	K	M	aAa/aTa	8,59	1	0	probably_damaging	1	neutral	0,15	neutral	1,45	deleterious	-5,62	deleterious	-5,88	high_impact	4,7	damaging	0,14	damaging	0,04	deleterious	3,86	23,5	0,23	0,45	disease	0,8	disease	0,82	disease	0,77	disease	0,67	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	-0,21	high_impact	3,3	0,58	0,8	68,72	19,76	P	0,88	P	0,75	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8098	8098	A	C	MI.6281	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	513	171	K	N	aaA/aaC	8,59	1	0	probably_damaging	1	neutral	0,45	neutral	1,58	deleterious	-4,13	deleterious	-4,91	high_impact	4,7	damaging	0,11	damaging	0,04	deleterious	3,93	23,5	0,44	0,55	disease	0,89	disease	0,83	disease	0,76	disease	0,62	2	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	0,16	high_impact	3,3	0,62	0,8	68,72	19,76	P	0,89	P	0,84	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8098	8098	A	T	MI.6282	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	513	171	K	N	aaA/aaT	8,59	1	0	probably_damaging	1	neutral	0,45	neutral	1,58	deleterious	-4,13	deleterious	-4,91	high_impact	4,7	damaging	0,11	damaging	0,04	deleterious	3,97	23,6	0,44	0,55	disease	0,89	disease	0,83	disease	0,76	disease	0,62	2	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	0,16	high_impact	3,3	0,62	0,8	68,72	19,76	P	0,9	P	0,84	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8099	8099	A	T	MI.6283	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	514	172	T	S	Aca/Tca	4,67	1	0	probably_damaging	0,99	neutral	0,43	neutral	1,94	neutral	-0,78	deleterious	-2,56	medium_impact	2,22	damaging	0,47	damaging	0,17	deleterious	1,83	15,16	0,56	0,6	disease	0,56	neutral	0,34	neutral	0,43	disease	0,59	2	deleterious	0,99	neutral	0,22	deleterious	1	deleterious	0,73	low_impact	-2,58	medium_impact	0,14	medium_impact	0,98	0,77	0,85	70,93	17,12	P	0,64	P	0,63	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8099	8099	A	C	MI.6284	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	514	172	T	P	Aca/Cca	4,67	1	0	probably_damaging	1	neutral	0,22	neutral	1,89	neutral	-2,59	deleterious	-4,15	medium_impact	3,02	damaging	0,3	damaging	0,1	deleterious	3,52	23,1	0,16	0,45	disease	0,78	disease	0,77	neutral	0,41	disease	0,53	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,86	low_impact	-3,52	medium_impact	-0,1	medium_impact	1,73	0,58	0,8	70,93	17,12	P	0,65	P	0,89	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8099	8099	A	G	MI.6285	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	514	172	T	A	Aca/Gca	4,67	1	0	probably_damaging	0,99	neutral	0,53	neutral	2,01	neutral	-0,13	deleterious	-2,92	neutral_impact	0,74	neutral	0,67	neutral	0,61	deleterious	0,42	6,82	0,71	0,75	neutral	0,47	neutral	0,15	neutral	0,23	neutral	0,26	5	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,7	low_impact	-2,58	medium_impact	0,23	medium_impact	-0,41	0,31	0,8	70,93	17,12	N	0,43	N	0,44	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8100	8100	C	A	MI.6286	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	515	172	T	K	aCa/aAa	5,6	1	0	probably_damaging	1	neutral	0,32	neutral	1,91	neutral	0,26	deleterious	-3,9	low_impact	1,29	damaging	0,41	damaging	0,1	deleterious	4,57	24,4	0,32	0,5	neutral	0,29	disease	0,64	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,73	low_impact	-3,52	medium_impact	0,02	medium_impact	0,1	0,65	0,8	70,93	17,12	P	0,63	P	0,88	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8100	8100	C	T	MI.6287	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	515	172	T	M	aCa/aTa	5,6	1	0	probably_damaging	1	neutral	0,27	neutral	2	neutral	0,82	neutral	-2,24	neutral_impact	-0,19	neutral	0,74	neutral	0,65	neutral	1,55	13,61	0,46	0,55	neutral	0,33	neutral	0,22	neutral	0,25	neutral	0,41	2	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,68	low_impact	-3,52	medium_impact	-0,03	low_impact	-1,28	0,84	0,9	70,93	17,12	P	0,55	P	0,96	disease_causing	0,98	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8102	8102	G	A	MI.6288	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	517	173	D	N	Gat/Aat	-2,01	0	0	possibly_damaging	0,9	neutral	0,49	neutral	1,7	deleterious	-3,2	deleterious	-4,9	high_impact	4,36	damaging	0,28	damaging	0,2	deleterious	4,27	23,9	0,62	0,65	disease	0,61	disease	0,84	disease	0,8	disease	0,69	4	neutral	0,89	neutral	0,3	deleterious	1	deleterious	0,81	low_impact	-1,61	medium_impact	0,2	high_impact	2,98	0,77	0,85	68,28	19,89	P	0,85	P	0,99	disease_causing	0,79	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8102	8102	G	T	MI.6289	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	517	173	D	Y	Gat/Tat	-2,01	0	0	probably_damaging	1	deleterious	0,04	neutral	1,64	deleterious	-4,75	deleterious	-8,82	high_impact	3,66	damaging	0,28	damaging	0,15	deleterious	4,08	23,7	0,27	0,45	disease	0,65	disease	0,93	disease	0,82	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,88	low_impact	-3,52	medium_impact	-0,56	high_impact	2,33	0,45	0,8	68,28	19,89	P	0,79	P	0,99	disease_causing	0,98	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8822	8822	C	T	MI.629	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	296	99	S	F	tCt/tTt	3,83	0,99	0	probably_damaging	1	neutral	0,33	neutral	3,8	deleterious	-3,03	deleterious	-5,12	medium_impact	3,23	damaging	0,59	neutral	0,47	deleterious	4,07	23,7	0,2	0,65	disease	0,78	disease	0,82	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,12	medium_impact	1,67	0,49	0,9	43,36	8,06	N	0,44	N	1	disease_causing	1	0,12	.	.	.	.	.	.	COSM1331626	.	.	.	.	.	.	.	.
chrM	8102	8102	G	C	MI.6290	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	517	173	D	H	Gat/Cat	-2,01	0	0	probably_damaging	1	neutral	0,12	neutral	1,65	deleterious	-5,17	deleterious	-6,86	high_impact	4,36	damaging	0,28	damaging	0,19	deleterious	3,85	23,4	0,32	0,5	disease	0,94	disease	0,87	disease	0,83	disease	0,63	3	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	-0,27	high_impact	2,98	0,49	0,8	68,28	19,89	P	0,86	P	0,98	disease_causing	0,95	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8103	8103	A	C	MI.6291	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	518	173	D	A	gAt/gCt	4,21	1	0	probably_damaging	0,95	neutral	0,8	neutral	1,71	deleterious	-3,7	deleterious	-7,84	high_impact	4,7	damaging	0,33	neutral	0,31	deleterious	3,74	23,3	0,24	0,45	disease	0,88	disease	0,83	disease	0,78	disease	0,65	3	neutral	0,94	neutral	0,43	deleterious	2	deleterious	0,87	low_impact	-1,91	medium_impact	0,54	high_impact	3,3	0,5	0,8	68,28	19,89	P	0,74	P	0,96	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8103	8103	A	G	MI.6292	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	518	173	D	G	gAt/gGt	4,21	1	0	benign	0,14	neutral	0,37	neutral	1,67	deleterious	-4,83	deleterious	-6,86	high_impact	4,36	damaging	0,3	neutral	0,28	deleterious	2,14	17,13	0,3	0,45	disease	0,9	disease	0,85	disease	0,79	disease	0,64	3	neutral	0,57	deleterious	0,62	neutral	-2	neutral	0,38	medium_impact	0,01	medium_impact	0,08	high_impact	2,98	0,47	0,8	68,28	19,89	P	0,74	P	0,97	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8103	8103	A	T	MI.6293	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	518	173	D	V	gAt/gTt	4,21	1	0	probably_damaging	1	neutral	0,33	neutral	1,66	deleterious	-4,81	deleterious	-8,82	high_impact	4,36	damaging	0,28	damaging	0,19	deleterious	3,84	23,4	0,22	0,45	disease	0,95	disease	0,91	disease	0,8	disease	0,64	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	0,04	high_impact	2,98	0,3	0,8	68,28	19,89	P	0,86	P	0,99	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8104	8104	T	G	MI.6294	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	519	173	D	E	gaT/gaG	6,98	1	0	possibly_damaging	0,72	neutral	1	neutral	1,81	deleterious	-3,26	deleterious	-3,92	high_impact	4,15	damaging	0,31	damaging	0,16	deleterious	3,82	23,4	0,48	0,55	disease	0,78	disease	0,81	disease	0,74	disease	0,69	4	neutral	0,71	deleterious	0,64	deleterious	1	deleterious	0,71	low_impact	-1,1	high_impact	1,86	high_impact	2,79	0,65	0,8	68,28	19,89	P	0,75	P	0,95	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8104	8104	T	A	MI.6295	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	519	173	D	E	gaT/gaA	6,98	1	0	possibly_damaging	0,72	neutral	1	neutral	1,81	deleterious	-3,26	deleterious	-3,92	high_impact	4,15	damaging	0,31	damaging	0,16	deleterious	3,96	23,6	0,48	0,55	disease	0,78	disease	0,81	disease	0,74	disease	0,69	4	neutral	0,71	deleterious	0,64	deleterious	1	deleterious	0,71	low_impact	-1,1	high_impact	1,86	high_impact	2,79	0,65	0,8	68,28	19,89	P	0,76	P	0,95	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8105	8105	G	C	MI.6296	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	520	174	A	P	Gca/Cca	-6,86	0	0	probably_damaging	1	neutral	0,26	neutral	1,58	deleterious	-5,64	deleterious	-4,91	high_impact	4,48	damaging	0,19	damaging	0,02	deleterious	4,02	23,6	0,11	0,4	disease	0,79	disease	0,87	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,05	high_impact	3,1	0,85	0,9	68,72	19,78	P	0,67	P	0,9	polymorphism	0,58	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8105	8105	G	A	MI.6297	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	520	174	A	T	Gca/Aca	-6,86	0	0	probably_damaging	1	neutral	0,42	neutral	1,64	neutral	-2,88	deleterious	-3,92	medium_impact	3,01	damaging	0,26	damaging	0,02	deleterious	4,41	24,1	0,42	0,5	neutral	0,34	disease	0,79	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,78	low_impact	-3,52	medium_impact	0,13	medium_impact	1,72	0,71	0,85	68,72	19,78	P	0,63	P	0,72	polymorphism	0,83	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8105	8105	G	T	MI.6298	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	520	174	A	S	Gca/Tca	-6,86	0	0	probably_damaging	1	neutral	0,46	neutral	1,63	deleterious	-3,82	deleterious	-2,94	medium_impact	2,28	damaging	0,31	damaging	0,03	deleterious	3,87	23,5	0,32	0,5	disease	0,75	disease	0,79	disease	0,6	disease	0,55	1	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,86	low_impact	-3,52	medium_impact	0,17	medium_impact	1,03	0,87	0,9	68,72	19,78	N	0,45	N	0,71	polymorphism	0,92	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8106	8106	C	T	MI.6299	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	521	174	A	V	gCa/gTa	6,06	1	0	probably_damaging	1	neutral	0,59	neutral	1,83	neutral	-1,58	deleterious	-3,93	medium_impact	2,98	damaging	0,24	damaging	0,01	deleterious	4,6	24,4	0,39	0,5	disease	0,51	disease	0,8	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,81	low_impact	-3,52	medium_impact	0,29	medium_impact	1,69	0,68	0,85	68,72	19,78	P	0,84	P	0,79	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8554	8554	A	G	MI.63	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	28	10	I	V	Att/Gtt	-0,33	0	0	benign	0	neutral	0,07	neutral	4,7	neutral	0,02	neutral	0,18	low_impact	1,43	neutral	0,95	neutral	0,83	deleterious	0,53	7,68	0,47	0,65	neutral	0,48	neutral	0,2	neutral	0,35	neutral	0,34	3	neutral	0,93	deleterious	0,54	neutral	-6	neutral	0,11	high_impact	2,09	medium_impact	-0,34	medium_impact	0,13	0,24	0,9	27,43	16,7	N	0,46	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8824	8824	A	G	MI.630	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	298	100	M	V	Ata/Gta	-15,14	0	0	possibly_damaging	0,87	neutral	0,52	neutral	4,55	neutral	1,8	neutral	-2,31	neutral_impact	0,18	neutral	0,9	neutral	0,59	deleterious	2,61	20,3	0,57	0,65	neutral	0,26	disease	0,55	disease	0,53	neutral	0,36	3	neutral	0,86	neutral	0,33	neutral	-3	deleterious	0,55	low_impact	-1,54	medium_impact	0,31	medium_impact	-0,94	0,66	0,9	27,43	8,87	N	0,33	N	0,95	polymorphism	0,81	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8106	8106	C	A	MI.6300	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	521	174	A	E	gCa/gAa	6,06	1	0	probably_damaging	1	neutral	0,32	neutral	1,59	deleterious	-5,14	deleterious	-4,91	high_impact	4,48	damaging	0,23	damaging	0,03	deleterious	4,58	24,4	0,12	0,4	disease	0,86	disease	0,88	disease	0,77	disease	0,68	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	0,02	high_impact	3,1	0,75	0,85	68,72	19,78	P	0,85	P	0,91	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8106	8106	C	G	MI.6301	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	521	174	A	G	gCa/gGa	6,06	1	0	probably_damaging	0,99	neutral	0,41	neutral	1,6	deleterious	-4,95	deleterious	-3,91	medium_impact	2,78	damaging	0,38	damaging	0,17	deleterious	4,05	23,7	0,25	0,45	disease	0,81	neutral	0,43	neutral	0,45	disease	0,56	1	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,79	low_impact	-2,58	medium_impact	0,12	medium_impact	1,5	0,86	0,9	68,72	19,78	P	0,71	P	0,74	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8108	8108	A	G	MI.6302	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	523	175	I	V	Att/Gtt	-8,93	0	0	benign	0,01	neutral	0,35	neutral	1,98	neutral	0,2	neutral	-0,04	neutral_impact	0,02	neutral	0,87	neutral	0,87	neutral	-1,44	0	0,53	0,6	neutral	0,32	neutral	0,12	neutral	0,27	neutral	0,22	6	neutral	0,64	deleterious	0,67	neutral	-6	neutral	0,12	medium_impact	1,14	medium_impact	0,06	low_impact	-1,09	0,58	0,8	71,37	11,62	N	0,44	N	0,19	polymorphism	1	0	.	.	.	.	.	MNGIE fibroblasts	.	.	.	A8108G	SNHL	+	-	Reported	1
chrM	8108	8108	A	C	MI.6303	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	523	175	I	L	Att/Ctt	-8,93	0	0	benign	0,16	neutral	0,34	neutral	1,89	neutral	-1,55	neutral	-1,96	medium_impact	2,21	damaging	0,57	neutral	0,35	deleterious	2,18	17,39	0,37	0,5	disease	0,57	disease	0,52	disease	0,62	disease	0,67	3	neutral	0,6	deleterious	0,59	neutral	-3	neutral	0,25	medium_impact	-0,05	medium_impact	0,05	medium_impact	0,97	0,83	0,9	71,37	11,62	N	0,32	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8108	8108	A	T	MI.6304	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	523	175	I	F	Att/Ttt	-8,93	0	0	possibly_damaging	0,74	neutral	0,06	neutral	1,83	neutral	-2,63	deleterious	-3,92	medium_impact	2,86	damaging	0,52	neutral	0,28	deleterious	4,06	23,7	0,31	0,45	disease	0,75	disease	0,69	disease	0,68	disease	0,7	4	neutral	0,95	neutral	0,16	NA	0	deleterious	0,75	low_impact	-1,14	medium_impact	-0,46	medium_impact	1,58	0,8	0,85	71,37	11,62	N	0,31	N	0,96	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8109	8109	T	C	MI.6305	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	524	175	I	T	aTt/aCt	1,91	0,94	0	probably_damaging	0,96	neutral	0,58	neutral	1,86	neutral	-2,58	deleterious	-3,97	low_impact	1,57	neutral	0,62	neutral	0,35	deleterious	2,19	17,44	0,37	0,5	disease	0,62	neutral	0,12	neutral	0,36	neutral	0,32	4	neutral	0,95	neutral	0,31	neutral	-2	deleterious	0,63	low_impact	-2,01	medium_impact	0,28	medium_impact	0,37	0,72	0,85	71,37	11,62	N	0,33	N	0,94	polymorphism	0,81	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8109	8109	T	G	MI.6306	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	524	175	I	S	aTt/aGt	1,91	0,94	0	probably_damaging	0,99	neutral	0,73	neutral	1,83	deleterious	-3,2	deleterious	-5,42	medium_impact	2,67	damaging	0,55	neutral	0,37	deleterious	4,46	24,2	0,25	0,45	disease	0,72	disease	0,75	disease	0,67	disease	0,6	2	deleterious	0,98	neutral	0,37	deleterious	1	deleterious	0,79	low_impact	-2,58	medium_impact	0,44	medium_impact	1,4	0,56	0,8	71,37	11,62	N	0,3	N	0,92	polymorphism	0,52	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8109	8109	T	A	MI.6307	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	524	175	I	N	aTt/aAt	1,91	0,94	0	probably_damaging	1	neutral	0,5	neutral	1,83	neutral	-2,58	deleterious	-6,4	medium_impact	2,23	damaging	0,54	neutral	0,3	deleterious	4,71	24,6	0,27	0,45	neutral	0,48	disease	0,82	disease	0,57	neutral	0,46	1	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,79	low_impact	-3,52	medium_impact	0,21	medium_impact	0,99	0,58	0,8	71,37	11,62	N	0,32	N	0,98	polymorphism	0,58	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8110	8110	T	G	MI.6308	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	525	175	I	M	atT/atG	4,67	0,98	0	possibly_damaging	0,9	neutral	0,12	neutral	1,89	neutral	-1,66	neutral	-2,48	medium_impact	2,18	damaging	0,58	neutral	0,35	deleterious	3,59	23,2	0,41	0,5	neutral	0,39	disease	0,51	disease	0,53	neutral	0,48	0	neutral	0,96	neutral	0,11	NA	0	deleterious	0,51	low_impact	-1,61	medium_impact	-0,27	medium_impact	0,94	0,84	0,9	71,37	11,62	P	0,54	P	0,79	polymorphism	0,55	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8110	8110	T	A	MI.6309	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	525	175	I	M	atT/atA	4,67	0,98	0	possibly_damaging	0,9	neutral	0,12	neutral	1,89	neutral	-1,66	neutral	-2,48	medium_impact	2,18	damaging	0,58	neutral	0,35	deleterious	3,86	23,5	0,41	0,5	neutral	0,39	disease	0,51	disease	0,53	neutral	0,48	0	neutral	0,96	neutral	0,11	NA	0	deleterious	0,51	low_impact	-1,61	medium_impact	-0,27	medium_impact	0,94	0,84	0,9	71,37	11,62	P	0,58	P	0,79	polymorphism	0,55	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8824	8824	A	T	MI.631	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	298	100	M	L	Ata/Tta	-15,14	0	0	possibly_damaging	0,81	neutral	0,99	neutral	4,61	neutral	1,09	neutral	-1,09	neutral_impact	-0,04	neutral	0,87	neutral	0,9	neutral	1,33	12,43	0,51	0,65	neutral	0,27	neutral	0,3	neutral	0,42	neutral	0,43	1	neutral	0,81	deleterious	0,59	neutral	-3	deleterious	0,49	low_impact	-1,35	medium_impact	1,42	low_impact	-1,13	0,65	0,9	27,43	8,87	N	0,28	N	0,93	polymorphism	0,84	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8111	8111	C	G	MI.6310	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	526	176	P	A	Ccc/Gcc	-6,63	0	0	probably_damaging	1	neutral	0,8	neutral	-0,07	deleterious	-5,81	deleterious	-7,85	high_impact	4,33	damaging	0,15	damaging	0,11	deleterious	3,26	22,8	0,17	0,45	disease	0,51	disease	0,64	disease	0,71	disease	0,66	3	deleterious	1	neutral	0,4	deleterious	2	deleterious	0,77	low_impact	-3,52	medium_impact	0,54	high_impact	2,95	0,68	0,85	68,28	19,64	P	0,57	P	0,9	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8111	8111	C	T	MI.6311	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	526	176	P	S	Ccc/Tcc	-6,63	0	0	probably_damaging	1	neutral	0,76	neutral	-0,12	deleterious	-7,03	deleterious	-7,85	medium_impact	3,32	damaging	0,11	damaging	0,03	deleterious	4,05	23,7	0,22	0,45	disease	0,76	disease	0,82	disease	0,71	disease	0,68	4	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,84	low_impact	-3,52	medium_impact	0,48	high_impact	2,01	0,33	0,8	68,28	19,64	P	0,5	N	0,94	polymorphism	0,99	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8111	8111	C	A	MI.6312	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	526	176	P	T	Ccc/Acc	-6,63	0	0	probably_damaging	1	neutral	0,59	neutral	-0,13	deleterious	-7,38	deleterious	-7,85	high_impact	3,87	damaging	0,11	damaging	0,02	deleterious	3,84	23,4	0,18	0,45	disease	0,57	disease	0,8	disease	0,71	disease	0,68	4	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,79	low_impact	-3,52	medium_impact	0,29	high_impact	2,52	0,66	0,8	68,28	19,64	P	0,51	P	0,96	polymorphism	0,99	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8112	8112	C	T	MI.6313	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	527	176	P	L	cCc/cTc	7,21	1	0	probably_damaging	1	neutral	0,42	neutral	-0,14	deleterious	-7,76	deleterious	-9,82	high_impact	4,33	damaging	0,09	damaging	0,02	deleterious	4,54	24,3	0,18	0,45	disease	0,94	disease	0,85	disease	0,69	disease	0,61	2	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	0,13	high_impact	2,95	0,72	0,85	68,28	19,64	P	0,76	P	0,92	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8112	8112	C	A	MI.6314	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	527	176	P	H	cCc/cAc	7,21	1	0	probably_damaging	1	neutral	0,16	neutral	-0,15	deleterious	-10,03	deleterious	-8,84	high_impact	4,33	damaging	0,09	damaging	0,02	deleterious	4,12	23,8	0,15	0,45	disease	0,96	disease	0,85	disease	0,77	disease	0,62	2	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	-0,19	high_impact	2,95	0,61	0,8	68,28	19,64	P	0,78	P	0,79	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8112	8112	C	G	MI.6315	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	527	176	P	R	cCc/cGc	7,21	1	0	probably_damaging	1	neutral	0,56	neutral	-0,15	deleterious	-8,74	deleterious	-8,84	high_impact	4,33	damaging	0,12	damaging	0,02	deleterious	3,73	23,3	0,14	0,4	disease	0,93	disease	0,88	disease	0,78	disease	0,63	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	0,26	high_impact	2,95	0,6	0,8	68,28	19,64	P	0,72	P	0,85	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8114	8114	G	C	MI.6316	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	529	177	G	R	Gga/Cga	-4,09	0	0	probably_damaging	1	neutral	0,42	neutral	1,35	deleterious	-4,52	deleterious	-7,85	high_impact	4,32	damaging	0,28	damaging	0,1	deleterious	4,11	23,7	0,14	0,4	disease	0,86	disease	0,9	disease	0,84	disease	0,67	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	0,13	high_impact	2,95	0,66	0,8	69,16	20,04	P	0,7	P	1	polymorphism	0,97	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8114	8114	G	T	MI.6317	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	529	177	G	W	Gga/Tga	-4,09	0	0	probably_damaging	1	neutral	0,18	neutral	1,31	deleterious	-8,42	deleterious	-7,85	high_impact	4,67	damaging	0,3	damaging	0,1	deleterious	4,58	24,4	0,12	0,4	disease	0,99	disease	0,9	disease	0,8	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	-0,16	high_impact	3,27	0,37	0,8	69,16	20,04	P	0,56	P	0,98	polymorphism	0,96	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8115	8115	G	C	MI.6318	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	530	177	G	A	gGa/gCa	9,29	1	0	probably_damaging	1	neutral	0,55	neutral	1,36	deleterious	-4,13	deleterious	-5,89	high_impact	3,98	damaging	0,31	damaging	0,28	deleterious	3,27	22,8	0,21	0,45	disease	0,62	disease	0,72	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	0,25	high_impact	2,63	0,7	0,85	69,16	20,04	P	0,79	P	0,85	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8115	8115	G	T	MI.6319	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	530	177	G	V	gGa/gTa	9,29	1	0	probably_damaging	1	neutral	0,54	neutral	1,32	deleterious	-5,37	deleterious	-8,83	high_impact	4,32	damaging	0,28	damaging	0,13	deleterious	3,91	23,5	0,12	0,4	disease	0,93	disease	0,88	disease	0,76	disease	0,61	2	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	0,24	high_impact	2,95	0,52	0,8	69,16	20,04	P	0,8	P	1	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8824	8824	A	C	MI.632	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	298	100	M	L	Ata/Cta	-15,14	0	0	possibly_damaging	0,81	neutral	0,99	neutral	4,61	neutral	1,09	neutral	-1,09	neutral_impact	-0,04	neutral	0,87	neutral	0,9	neutral	1,19	11,71	0,51	0,65	neutral	0,27	neutral	0,3	neutral	0,42	neutral	0,43	1	neutral	0,81	deleterious	0,59	neutral	-3	deleterious	0,49	low_impact	-1,35	medium_impact	1,42	low_impact	-1,13	0,65	0,9	27,43	8,87	N	0,28	N	0,93	polymorphism	0,84	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8115	8115	G	A	MI.6320	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	530	177	G	E	gGa/gAa	9,29	1	0	probably_damaging	1	neutral	0,27	neutral	1,39	deleterious	-3,49	deleterious	-7,85	high_impact	4,67	damaging	0,32	damaging	0,11	deleterious	4,01	23,6	0,15	0,45	disease	0,76	disease	0,89	disease	0,82	disease	0,72	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	-0,03	high_impact	3,27	0,66	0,8	69,16	20,04	P	0,8	P	1	disease_causing	1	0,22	.	.	.	.	.	.	COSM218997	.	.	.	.	.	.	.	.
chrM	8117	8117	C	A	MI.6321	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	532	178	R	S	Cgt/Agt	-7,32	0	0	probably_damaging	1	neutral	0,84	neutral	1,8	neutral	-1,77	deleterious	-5,88	high_impact	3,87	damaging	0,12	damaging	0,01	deleterious	4,72	24,6	0,3	0,45	disease	0,72	disease	0,84	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	0,6	high_impact	2,52	0,43	0,8	67,84	20,05	P	0,68	P	0,77	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8117	8117	C	T	MI.6322	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	532	178	R	C	Cgt/Tgt	-7,32	0	0	probably_damaging	1	neutral	0,1	neutral	1,72	deleterious	-4,96	deleterious	-7,84	high_impact	4,57	damaging	0,14	damaging	0	deleterious	5,18	25,5	0,36	0,5	disease	0,96	disease	0,87	disease	0,71	disease	0,61	2	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	-0,32	high_impact	3,18	0,73	0,85	67,84	20,05	P	0,68	P	1	disease_causing	0,57	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8117	8117	C	G	MI.6323	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	532	178	R	G	Cgt/Ggt	-7,32	0	0	probably_damaging	1	neutral	0,51	neutral	1,75	neutral	-2,93	deleterious	-6,86	high_impact	4,22	damaging	0,15	damaging	0	deleterious	4,33	24	0,31	0,5	disease	0,84	disease	0,78	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	0,21	high_impact	2,85	0,38	0,8	67,84	20,05	P	0,59	P	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8118	8118	G	C	MI.6324	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	533	178	R	P	cGt/cCt	3,52	0,99	0	probably_damaging	1	neutral	0,33	neutral	1,74	deleterious	-3,5	deleterious	-6,86	high_impact	4,57	damaging	0,14	damaging	0,01	deleterious	4,36	24,1	0,22	0,45	disease	0,88	disease	0,87	disease	0,7	disease	0,62	2	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	0,04	high_impact	3,18	0,31	0,8	67,84	20,05	P	0,83	P	1	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8118	8118	G	A	MI.6325	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	533	178	R	H	cGt/cAt	3,52	0,99	0	probably_damaging	1	neutral	0,28	neutral	1,74	deleterious	-3,16	deleterious	-4,9	medium_impact	3,37	damaging	0,14	damaging	0	deleterious	4,56	24,4	0,44	0,55	disease	0,78	disease	0,8	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,85	low_impact	-3,52	medium_impact	-0,02	high_impact	2,05	0,77	0,85	67,84	20,05	P	0,88	P	0,99	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8118	8118	G	T	MI.6326	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	533	178	R	L	cGt/cTt	3,52	0,99	0	probably_damaging	1	neutral	0,58	neutral	1,77	neutral	-2,38	deleterious	-6,86	medium_impact	3,12	damaging	0,13	damaging	0,01	deleterious	4,43	24,2	0,32	0,5	disease	0,83	disease	0,89	disease	0,67	disease	0,65	3	deleterious	0,99	neutral	0,29	deleterious	1	deleterious	0,86	low_impact	-3,52	medium_impact	0,28	medium_impact	1,82	0,32	0,8	67,84	20,05	P	0,85	P	1	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8120	8120	C	A	MI.6327	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	535	179	L	M	Cta/Ata	-6,86	0	0	probably_damaging	1	neutral	0,24	neutral	1,7	neutral	-2,92	neutral	-1,93	medium_impact	2,9	damaging	0,24	damaging	0,06	deleterious	3,88	23,5	0,36	0,5	disease	0,73	disease	0,6	neutral	0,48	neutral	0,39	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,78	low_impact	-3,52	medium_impact	-0,07	medium_impact	1,61	0,8	0,85	68,28	19,75	P	0,63	P	0,78	polymorphism	1	0,02	rs8936	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8120	8120	C	G	MI.6328	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	535	179	L	V	Cta/Gta	-6,86	0	0	probably_damaging	0,99	neutral	0,53	neutral	1,86	neutral	-0,82	deleterious	-2,91	medium_impact	2,06	damaging	0,18	damaging	0,01	deleterious	3,55	23,1	0,4	0,5	neutral	0,44	disease	0,6	disease	0,51	disease	0,52	0	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,76	low_impact	-2,58	medium_impact	0,23	medium_impact	0,83	0,64	0,8	68,28	19,75	P	0,67	P	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8121	8121	T	A	MI.6329	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	536	179	L	Q	cTa/cAa	-1,09	0	0	probably_damaging	1	neutral	0,32	neutral	1,69	deleterious	-3,38	deleterious	-5,84	high_impact	3,65	damaging	0,2	damaging	0,02	deleterious	4,13	23,8	0,26	0,45	disease	0,81	disease	0,85	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	0,02	high_impact	2,32	0,52	0,8	68,28	19,75	P	0,74	P	0,95	disease_causing	0,98	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8825	8825	T	A	MI.633	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	299	100	M	K	aTa/aAa	0,82	0,08	0	probably_damaging	0,94	deleterious	0	neutral	4,34	neutral	-2,19	deleterious	-4,62	medium_impact	3,34	neutral	0,75	damaging	0,09	deleterious	3,81	23,4	0,15	0,65	disease	0,72	disease	0,82	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,81	low_impact	-1,89	low_impact	-1,4	medium_impact	1,77	0,62	0,9	27,43	8,87	N	0,32	N	0,98	disease_causing	0,91	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8121	8121	T	C	MI.6330	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	536	179	L	P	cTa/cCa	-1,09	0	0	probably_damaging	1	neutral	0,22	neutral	1,67	deleterious	-4,22	deleterious	-6,82	high_impact	3,54	damaging	0,16	damaging	0,01	deleterious	4	23,6	0,21	0,45	disease	0,86	disease	0,83	disease	0,63	disease	0,63	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	-0,1	high_impact	2,21	0,45	0,8	68,28	19,75	P	0,72	P	0,99	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8121	8121	T	G	MI.6331	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	536	179	L	R	cTa/cGa	-1,09	0	0	probably_damaging	1	neutral	0,39	neutral	1,69	deleterious	-3,37	deleterious	-5,84	medium_impact	3,46	damaging	0,17	damaging	0,01	deleterious	4,26	23,9	0,25	0,45	disease	0,8	disease	0,87	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,89	low_impact	-3,52	medium_impact	0,1	high_impact	2,14	0,49	0,8	68,28	19,75	P	0,76	P	0,99	disease_causing	0,98	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8123	8123	A	T	MI.6332	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	538	180	N	Y	Aac/Tac	-2,24	0	0	probably_damaging	1	neutral	0,22	neutral	1,71	deleterious	-4,79	deleterious	-7,8	high_impact	4,26	damaging	0,14	damaging	0,05	deleterious	3,86	23,5	0,35	0,5	disease	0,85	disease	0,78	disease	0,75	disease	0,66	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	-0,1	high_impact	2,89	0,47	0,8	68,28	19,58	P	0,76	P	0,98	disease_causing	0,51	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8123	8123	A	G	MI.6333	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	538	180	N	D	Aac/Gac	-2,24	0	0	probably_damaging	0,99	neutral	0,66	neutral	1,78	deleterious	-3,14	deleterious	-4,87	high_impact	4,06	damaging	0,19	damaging	0,05	deleterious	3,98	23,6	0,53	0,6	disease	0,78	disease	0,64	disease	0,74	disease	0,67	3	deleterious	0,99	neutral	0,34	deleterious	2	deleterious	0,78	low_impact	-2,58	medium_impact	0,36	high_impact	2,7	0,55	0,8	68,28	19,58	P	0,73	P	0,97	polymorphism	0,89	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8123	8123	A	C	MI.6334	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	538	180	N	H	Aac/Cac	-2,24	0	0	probably_damaging	1	neutral	0,21	neutral	1,72	deleterious	-4,07	deleterious	-4,87	high_impact	3,92	damaging	0,13	damaging	0,05	deleterious	3,23	22,8	0,43	0,55	disease	0,77	disease	0,68	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,81	low_impact	-3,52	medium_impact	-0,11	high_impact	2,57	0,44	0,8	68,28	19,58	P	0,8	P	0,94	polymorphism	0,8	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8124	8124	A	G	MI.6335	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	539	180	N	S	aAc/aGc	6,98	1	0	probably_damaging	0,98	neutral	0,85	neutral	1,8	neutral	-2,22	deleterious	-4,84	medium_impact	2,96	damaging	0,16	damaging	0,05	deleterious	3,12	22,6	0,58	0,65	disease	0,64	disease	0,7	disease	0,64	disease	0,65	3	deleterious	0,98	neutral	0,44	deleterious	1	deleterious	0,79	low_impact	-2,3	medium_impact	0,62	medium_impact	1,67	0,35	0,8	68,28	19,58	P	0,83	P	0,87	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8124	8124	A	T	MI.6336	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	539	180	N	I	aAc/aTc	6,98	1	0	probably_damaging	1	neutral	0,31	neutral	1,72	deleterious	-3,78	deleterious	-8,78	high_impact	3,92	damaging	0,16	damaging	0,02	deleterious	3,96	23,6	0,37	0,5	disease	0,75	disease	0,77	disease	0,71	disease	0,68	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,81	low_impact	-3,52	medium_impact	0,01	high_impact	2,57	0,4	0,8	68,28	19,58	P	0,83	P	0,97	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8124	8124	A	C	MI.6337	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	539	180	N	T	aAc/aCc	6,98	1	0	probably_damaging	1	neutral	0,64	neutral	1,76	neutral	-1,12	deleterious	-5,83	medium_impact	2,96	damaging	0,13	damaging	0,03	deleterious	3,48	23,1	0,51	0,6	neutral	0,38	disease	0,71	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,73	low_impact	-3,52	medium_impact	0,34	medium_impact	1,67	0,64	0,8	68,28	19,58	P	0,84	P	0,92	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8125	8125	C	G	MI.6338	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	540	180	N	K	aaC/aaG	8,59	1	0	probably_damaging	1	neutral	0,93	neutral	1,79	neutral	-2,3	deleterious	-5,84	high_impact	4,26	damaging	0,13	damaging	0,02	deleterious	4,18	23,8	0,59	0,65	disease	0,68	disease	0,74	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,47	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	0,83	high_impact	2,89	0,58	0,8	68,28	19,58	P	0,8	P	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8125	8125	C	A	MI.6339	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	540	180	N	K	aaC/aaA	8,59	1	0	probably_damaging	1	neutral	0,93	neutral	1,79	neutral	-2,3	deleterious	-5,84	high_impact	4,26	damaging	0,13	damaging	0,02	deleterious	4,62	24,5	0,59	0,65	disease	0,68	disease	0,74	disease	0,73	disease	0,68	4	deleterious	1	neutral	0,47	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	0,83	high_impact	2,89	0,58	0,8	68,28	19,58	P	0,8	P	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8825	8825	T	C	MI.634	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	299	100	M	T	aTa/aCa	0,82	0,08	0	probably_damaging	0,94	deleterious	0,03	neutral	4,43	neutral	0,35	deleterious	-4,19	medium_impact	2,24	neutral	0,87	neutral	0,49	neutral	1,78	14,87	0,37	0,65	neutral	0,28	disease	0,67	disease	0,54	neutral	0,41	2	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,68	low_impact	-1,89	medium_impact	-0,56	medium_impact	0,82	0,52	0,9	27,43	8,87	N	0,46	N	0,97	disease_causing	0,57	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8126	8126	C	A	MI.6340	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	541	181	Q	K	Caa/Aaa	-2,48	0	0	probably_damaging	0,98	neutral	0,3	neutral	1,89	neutral	-0,33	deleterious	-3,92	medium_impact	2,9	damaging	0,16	damaging	0,02	deleterious	4,2	23,9	0,54	0,6	neutral	0,33	disease	0,77	disease	0,69	disease	0,66	3	deleterious	0,98	neutral	0,16	deleterious	1	deleterious	0,76	low_impact	-2,3	medium_impact	0	medium_impact	1,61	0,62	0,8	69,16	19,48	P	0,76	P	0,97	polymorphism	0,74	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8126	8126	C	G	MI.6341	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	541	181	Q	E	Caa/Gaa	-2,48	0	0	probably_damaging	0,95	neutral	0,28	neutral	1,88	neutral	0,5	deleterious	-2,93	low_impact	1,84	damaging	0,16	damaging	0,04	deleterious	3,21	22,7	0,5	0,6	neutral	0,45	disease	0,64	disease	0,68	disease	0,65	3	neutral	0,96	neutral	0,17	neutral	-2	deleterious	0,75	low_impact	-1,91	medium_impact	-0,02	medium_impact	0,62	0,63	0,8	69,16	19,48	P	0,77	P	0,85	polymorphism	0,86	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8127	8127	A	G	MI.6342	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	542	181	Q	R	cAa/cGa	7,21	1	0	probably_damaging	0,98	neutral	0,35	neutral	1,85	neutral	-1,15	deleterious	-3,92	medium_impact	2,41	damaging	0,15	damaging	0,03	deleterious	3,63	23,2	0,53	0,6	neutral	0,47	disease	0,75	disease	0,71	disease	0,67	3	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,79	low_impact	-2,3	medium_impact	0,06	medium_impact	1,15	0,59	0,8	69,16	19,48	P	0,88	P	0,95	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8127	8127	A	C	MI.6343	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	542	181	Q	P	cAa/cCa	7,21	1	0	probably_damaging	0,99	neutral	0,21	neutral	1,77	neutral	-2,33	deleterious	-5,88	high_impact	4,19	damaging	0,16	damaging	0,03	deleterious	3,48	23,1	0,2	0,45	disease	0,79	disease	0,78	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-2,58	medium_impact	-0,11	high_impact	2,82	0,36	0,8	69,16	19,48	P	0,86	P	0,95	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8127	8127	A	T	MI.6344	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	542	181	Q	L	cAa/cTa	7,21	1	0	probably_damaging	0,98	neutral	0,66	neutral	1,79	neutral	-2,5	deleterious	-6,86	medium_impact	2,81	damaging	0,13	damaging	0,03	deleterious	3,95	23,6	0,32	0,5	disease	0,67	disease	0,77	disease	0,66	disease	0,66	3	neutral	0,97	neutral	0,34	deleterious	1	deleterious	0,8	low_impact	-2,3	medium_impact	0,36	medium_impact	1,53	0,28	0,8	69,16	19,48	P	0,84	P	0,97	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8128	8128	A	T	MI.6345	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	543	181	Q	H	caA/caT	8,59	1	0	probably_damaging	1	neutral	0,54	neutral	1,77	neutral	-1,81	deleterious	-4,9	medium_impact	2,75	damaging	0,12	damaging	0,03	deleterious	3,68	23,3	0,48	0,55	neutral	0,39	disease	0,69	disease	0,71	disease	0,67	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,77	low_impact	-3,52	medium_impact	0,24	medium_impact	1,47	0,68	0,85	69,16	19,48	P	0,88	P	0,86	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8128	8128	A	C	MI.6346	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	543	181	Q	H	caA/caC	8,59	1	0	probably_damaging	1	neutral	0,54	neutral	1,77	neutral	-1,81	deleterious	-4,9	medium_impact	2,75	damaging	0,12	damaging	0,03	deleterious	3,46	23	0,48	0,55	neutral	0,39	disease	0,69	disease	0,71	disease	0,67	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,77	low_impact	-3,52	medium_impact	0,24	medium_impact	1,47	0,68	0,85	69,16	19,48	P	0,88	P	0,86	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8129	8129	A	G	MI.6347	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	544	182	T	A	Acc/Gcc	3,29	1	0	benign	0,01	neutral	0,78	neutral	1,98	neutral	-0,66	deleterious	-2,9	neutral_impact	0,02	neutral	0,75	neutral	0,97	deleterious	0,19	4,54	0,55	0,6	neutral	0,43	neutral	0,22	neutral	0,29	neutral	0,38	2	neutral	0,2	deleterious	0,89	neutral	-6	neutral	0,15	medium_impact	1,14	medium_impact	0,51	low_impact	-1,09	0,51	0,8	24,67	43,28	N	0,44	N	0	disease_causing	0,76	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8129	8129	A	C	MI.6348	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	544	182	T	P	Acc/Ccc	3,29	1	0	possibly_damaging	0,66	neutral	0,31	neutral	1,88	deleterious	-3,92	deleterious	-4,67	medium_impact	2,64	damaging	0,42	neutral	0,29	deleterious	3,37	22,9	0,15	0,4	neutral	0,38	disease	0,78	disease	0,56	disease	0,62	2	neutral	0,74	neutral	0,33	NA	0	deleterious	0,61	medium_impact	-0,99	medium_impact	0,01	medium_impact	1,37	0,65	0,8	24,67	43,28	P	0,57	P	0,74	disease_causing	0,94	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8129	8129	A	T	MI.6349	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	544	182	T	S	Acc/Tcc	3,29	1	0	benign	0,12	neutral	0,83	neutral	1,93	neutral	-1,81	deleterious	-2,73	neutral_impact	0,78	damaging	0,6	neutral	0,63	neutral	1,43	12,97	0,44	0,55	disease	0,57	neutral	0,43	neutral	0,27	disease	0,57	1	neutral	0,07	deleterious	0,86	neutral	-6	neutral	0,24	medium_impact	0,09	medium_impact	0,59	medium_impact	-0,37	0,7	0,85	24,67	43,28	N	0,36	N	0,29	disease_causing	0,51	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8826	8826	A	C	MI.635	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	300	100	M	I	atA/atC	3,83	0,49	0	probably_damaging	0,91	neutral	0,55	neutral	4,51	neutral	1,04	neutral	-2,05	low_impact	0,88	neutral	0,84	damaging	0,18	deleterious	2,1	16,87	0,53	0,65	neutral	0,37	disease	0,61	neutral	0,47	neutral	0,34	3	neutral	0,9	neutral	0,32	neutral	-2	deleterious	0,63	low_impact	-1,71	medium_impact	0,34	medium_impact	-0,34	0,78	0,9	27,43	8,87	N	0,26	N	0,91	disease_causing	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8130	8130	C	T	MI.6350	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	545	182	T	I	aCc/aTc	0,98	0,98	0	possibly_damaging	0,61	neutral	0,22	neutral	2,05	neutral	-0,51	deleterious	-4,38	neutral_impact	0,53	neutral	0,63	neutral	0,71	deleterious	2,62	20,3	0,34	0,5	neutral	0,34	neutral	0,46	neutral	0,26	neutral	0,41	2	neutral	0,79	neutral	0,31	neutral	-3	deleterious	0,5	medium_impact	-0,9	medium_impact	-0,1	medium_impact	-0,61	0,61	0,8	24,67	43,28	N	0,46	N	0,38	polymorphism	0,96	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8130	8130	C	G	MI.6351	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	545	182	T	S	aCc/aGc	0,98	0,98	0	benign	0,12	neutral	0,83	neutral	1,93	neutral	-1,81	deleterious	-2,73	neutral_impact	0,78	damaging	0,6	neutral	0,63	neutral	1,76	14,75	0,44	0,55	disease	0,57	neutral	0,43	neutral	0,27	disease	0,57	1	neutral	0,07	deleterious	0,86	neutral	-6	neutral	0,24	medium_impact	0,09	medium_impact	0,59	medium_impact	-0,37	0,7	0,85	24,67	43,28	N	0,37	N	0,29	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8130	8130	C	A	MI.6352	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	545	182	T	N	aCc/aAc	0,98	0,98	0	possibly_damaging	0,66	neutral	0,51	neutral	1,89	neutral	-2,45	deleterious	-4,11	medium_impact	2,3	damaging	0,53	neutral	0,42	deleterious	3,67	23,2	0,33	0,5	disease	0,73	disease	0,69	disease	0,58	disease	0,63	3	neutral	0,63	neutral	0,43	NA	0	deleterious	0,56	medium_impact	-0,99	medium_impact	0,21	medium_impact	1,05	0,73	0,85	24,67	43,28	N	0,44	N	0,59	polymorphism	0,96	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8132	8132	A	T	MI.6353	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	547	183	T	S	Act/Tct	-6,63	0	0	benign	0,1	neutral	0,42	neutral	1,95	neutral	0,35	neutral	-1,96	neutral_impact	-0,28	neutral	0,71	neutral	0,77	neutral	-0,44	0,31	0,49	0,55	neutral	0,39	neutral	0,06	neutral	0,17	neutral	0,21	6	neutral	0,52	deleterious	0,66	neutral	-6	neutral	0,15	medium_impact	0,17	medium_impact	0,13	low_impact	-1,37	0,63	0,8	26,87	28,4	N	0,49	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8132	8132	A	G	MI.6354	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	547	183	T	A	Act/Gct	-6,63	0	0	benign	0	neutral	0,51	neutral	1,89	neutral	-0,5	deleterious	-2,66	medium_impact	2,15	neutral	0,79	neutral	0,81	neutral	-0,13	1,52	0,62	0,65	disease	0,59	neutral	0,25	neutral	0,4	disease	0,55	1	neutral	0,49	deleterious	0,76	neutral	-3	neutral	0,19	high_impact	2,08	medium_impact	0,21	medium_impact	0,91	0,46	0,8	26,87	28,4	N	0,32	N	0,8	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8132	8132	A	C	MI.6355	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	547	183	T	P	Act/Cct	-6,63	0	0	possibly_damaging	0,62	neutral	0,2	neutral	1,85	neutral	-2,45	deleterious	-4,33	low_impact	1,54	damaging	0,59	neutral	0,32	deleterious	3,26	22,8	0,18	0,45	disease	0,83	disease	0,77	neutral	0,4	neutral	0,46	1	neutral	0,81	neutral	0,29	neutral	-3	deleterious	0,51	medium_impact	-0,92	medium_impact	-0,13	medium_impact	0,34	0,56	0,8	26,87	28,4	N	0,3	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8133	8133	C	T	MI.6356	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	548	183	T	I	aCt/aTt	2,37	0,28	0	benign	0,21	neutral	0,4	neutral	1,89	neutral	-1,68	deleterious	-4,25	low_impact	1,84	neutral	0,81	neutral	0,65	deleterious	2,28	18,02	0,44	0,55	disease	0,78	neutral	0,5	neutral	0,41	neutral	0,41	2	neutral	0,52	deleterious	0,6	neutral	-6	neutral	0,31	medium_impact	-0,18	medium_impact	0,11	medium_impact	0,62	0,68	0,85	26,87	28,4	N	0,29	N	0,73	polymorphism	1	0,04	rs386829026	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8133	8133	C	G	MI.6357	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	548	183	T	S	aCt/aGt	2,37	0,28	0	benign	0,1	neutral	0,42	neutral	1,95	neutral	0,35	neutral	-1,96	neutral_impact	-0,28	neutral	0,71	neutral	0,77	neutral	-0,22	1	0,49	0,55	neutral	0,39	neutral	0,06	neutral	0,17	neutral	0,21	6	neutral	0,52	deleterious	0,66	neutral	-6	neutral	0,15	medium_impact	0,17	medium_impact	0,13	low_impact	-1,37	0,63	0,8	26,87	28,4	N	0,46	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8133	8133	C	A	MI.6358	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	548	183	T	N	aCt/aAt	2,37	0,28	0	possibly_damaging	0,62	neutral	0,31	neutral	1,9	neutral	-0,99	deleterious	-3,52	neutral_impact	0,37	neutral	0,68	neutral	0,43	deleterious	2,2	17,5	0,55	0,6	disease	0,66	neutral	0,28	neutral	0,25	disease	0,58	1	neutral	0,72	neutral	0,35	neutral	-3	neutral	0,38	medium_impact	-0,92	medium_impact	0,01	medium_impact	-0,76	0,58	0,8	26,87	28,4	N	0,33	N	0,88	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8135	8135	T	A	MI.6359	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	550	184	F	I	Ttc/Atc	-12,16	0	0	probably_damaging	0,99	neutral	0,47	neutral	1,81	neutral	-1,7	deleterious	-4,35	low_impact	0,95	damaging	0,43	neutral	0,54	deleterious	4,5	24,3	0,23	0,45	disease	0,55	disease	0,64	neutral	0,41	neutral	0,2	6	deleterious	0,99	neutral	0,24	neutral	-2	deleterious	0,77	low_impact	-2,58	medium_impact	0,18	medium_impact	-0,22	0,65	0,8	29,07	68,25	N	0,49	N	0,34	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8826	8826	A	T	MI.636	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	300	100	M	I	atA/atT	3,83	0,49	0	probably_damaging	0,91	neutral	0,55	neutral	4,51	neutral	1,04	neutral	-2,05	low_impact	0,88	neutral	0,84	damaging	0,18	deleterious	2,19	17,43	0,53	0,65	neutral	0,37	disease	0,61	neutral	0,47	neutral	0,34	3	neutral	0,9	neutral	0,32	neutral	-2	deleterious	0,63	low_impact	-1,71	medium_impact	0,34	medium_impact	-0,34	0,78	0,9	27,43	8,87	N	0,27	N	0,91	disease_causing	0,99	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8135	8135	T	G	MI.6360	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	550	184	F	V	Ttc/Gtc	-12,16	0	0	probably_damaging	0,99	neutral	0,53	neutral	1,81	neutral	-1,41	deleterious	-5,29	low_impact	1,57	neutral	0,65	neutral	0,89	deleterious	4,26	23,9	0,28	0,45	neutral	0,49	disease	0,83	disease	0,59	disease	0,56	1	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,78	low_impact	-2,58	medium_impact	0,23	medium_impact	0,37	0,59	0,8	29,07	68,25	N	0,31	N	0,01	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8135	8135	T	C	MI.6361	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	550	184	F	L	Ttc/Ctc	-12,16	0	0	probably_damaging	0,99	neutral	0,76	neutral	1,93	neutral	-1,34	deleterious	-4,08	neutral_impact	0,35	neutral	0,71	neutral	0,94	deleterious	2,81	21,4	0,48	0,55	neutral	0,28	neutral	0,5	neutral	0,37	neutral	0,2	6	deleterious	0,99	neutral	0,39	neutral	-2	deleterious	0,7	low_impact	-2,58	medium_impact	0,48	medium_impact	-0,78	0,84	0,9	29,07	68,25	N	0,31	N	0,02	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8136	8136	T	G	MI.6362	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	551	184	F	C	tTc/tGc	-0,4	0	0	probably_damaging	1	neutral	0,19	neutral	1,69	deleterious	-4,99	deleterious	-6,52	medium_impact	3,12	damaging	0,33	damaging	0,19	deleterious	4,24	23,9	0,2	0,45	disease	0,87	disease	0,86	disease	0,69	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,85	low_impact	-3,52	medium_impact	-0,14	medium_impact	1,82	0,36	0,8	29,07	68,25	P	0,52	P	0,57	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8136	8136	T	C	MI.6363	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	551	184	F	S	tTc/tCc	-0,4	0	0	probably_damaging	1	neutral	0,49	neutral	1,73	deleterious	-3,65	deleterious	-6,7	medium_impact	2,57	damaging	0,34	damaging	0,24	deleterious	4,4	24,1	0,14	0,4	disease	0,74	disease	0,84	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,85	low_impact	-3,52	medium_impact	0,2	medium_impact	1,3	0,49	0,8	29,07	68,25	N	0,5	N	0,59	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8136	8136	T	A	MI.6364	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	551	184	F	Y	tTc/tAc	-0,4	0	0	probably_damaging	0,99	neutral	1	neutral	1,74	deleterious	-3,09	deleterious	-2,55	medium_impact	2,49	damaging	0,36	damaging	0,26	deleterious	4,33	24	0,3	0,45	disease	0,71	disease	0,74	disease	0,68	disease	0,64	3	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,81	low_impact	-2,58	high_impact	1,86	medium_impact	1,23	0,75	0,85	29,07	68,25	P	0,51	P	0,37	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8137	8137	C	A	MI.6365	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	552	184	F	L	ttC/ttA	7,44	0,96	0	probably_damaging	0,99	neutral	0,76	neutral	1,93	neutral	-1,34	deleterious	-4,08	neutral_impact	0,35	neutral	0,71	neutral	0,94	deleterious	3,34	22,9	0,48	0,55	neutral	0,28	neutral	0,5	neutral	0,37	neutral	0,2	6	deleterious	0,99	neutral	0,39	neutral	-2	deleterious	0,7	low_impact	-2,58	medium_impact	0,48	medium_impact	-0,78	0,84	0,9	29,07	68,25	N	0,46	N	0,02	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8137	8137	C	G	MI.6366	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	552	184	F	L	ttC/ttG	7,44	0,96	0	probably_damaging	0,99	neutral	0,76	neutral	1,93	neutral	-1,34	deleterious	-4,08	neutral_impact	0,35	neutral	0,71	neutral	0,94	deleterious	3,06	22,4	0,48	0,55	neutral	0,28	neutral	0,5	neutral	0,37	neutral	0,2	6	deleterious	0,99	neutral	0,39	neutral	-2	deleterious	0,7	low_impact	-2,58	medium_impact	0,48	medium_impact	-0,78	0,84	0,9	29,07	68,25	N	0,45	N	0,02	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8138	8138	A	G	MI.6367	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	553	185	T	A	Acc/Gcc	-7,09	0	0	probably_damaging	0,99	neutral	0,64	neutral	1,88	neutral	-2,02	neutral	-1,22	low_impact	1,41	neutral	0,77	neutral	0,86	deleterious	2,52	19,57	0,62	0,65	neutral	0,46	neutral	0,16	neutral	0,42	neutral	0,3	4	deleterious	0,99	neutral	0,33	neutral	-2	deleterious	0,67	low_impact	-2,58	medium_impact	0,34	medium_impact	0,22	0,48	0,8	30,84	46,13	N	0,27	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8138	8138	A	C	MI.6368	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	553	185	T	P	Acc/Ccc	-7,09	0	0	probably_damaging	1	neutral	0,25	neutral	1,84	deleterious	-3,71	deleterious	-2,87	medium_impact	2,65	damaging	0,59	neutral	0,38	deleterious	3,61	23,2	0,15	0,4	disease	0,71	disease	0,58	neutral	0,43	neutral	0,43	2	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	-0,06	medium_impact	1,38	0,56	0,8	30,84	46,13	N	0,32	N	0,86	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8138	8138	A	T	MI.6369	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	553	185	T	S	Acc/Tcc	-7,09	0	0	probably_damaging	0,99	neutral	0,55	neutral	1,87	neutral	-1,65	neutral	-1,56	neutral_impact	0,06	neutral	0,77	neutral	0,82	deleterious	2,21	17,57	0,47	0,55	neutral	0,35	neutral	0,14	neutral	0,25	neutral	0,28	4	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,65	low_impact	-2,58	medium_impact	0,25	low_impact	-1,05	0,65	0,8	30,84	46,13	N	0,29	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8827	8827	A	C	MI.637	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	301	101	N	H	Aac/Cac	-0,8	0,02	0	probably_damaging	1	deleterious	0	neutral	4,31	neutral	-2,19	deleterious	-4,43	high_impact	3,84	damaging	0,57	neutral	0,34	deleterious	3,03	22,3	0,38	0,65	disease	0,77	disease	0,73	disease	0,77	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,78	low_impact	-3,6	low_impact	-1,4	high_impact	2,19	0,55	0,9	49,56	8,63	N	0,41	N	0,98	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8139	8139	C	T	MI.6370	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	554	185	T	I	aCc/aTc	1,91	0	0	probably_damaging	1	neutral	0,7	neutral	1,94	deleterious	-3,02	neutral	0,75	neutral_impact	0,08	neutral	0,76	neutral	0,8	neutral	1,4	12,79	0,47	0,55	disease	0,57	neutral	0,12	neutral	0,27	neutral	0,34	3	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,67	low_impact	-3,52	medium_impact	0,41	low_impact	-1,03	0,68	0,85	30,84	46,13	N	0,31	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8139	8139	C	G	MI.6371	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	554	185	T	S	aCc/aGc	1,91	0	0	probably_damaging	0,99	neutral	0,55	neutral	1,87	neutral	-1,65	neutral	-1,56	neutral_impact	0,06	neutral	0,77	neutral	0,82	deleterious	2,43	19,01	0,47	0,55	neutral	0,35	neutral	0,14	neutral	0,25	neutral	0,28	4	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,65	low_impact	-2,58	medium_impact	0,25	low_impact	-1,05	0,65	0,8	30,84	46,13	N	0,3	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8139	8139	C	A	MI.6372	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	554	185	T	N	aCc/aAc	1,91	0	0	probably_damaging	1	neutral	0,35	neutral	1,86	neutral	-1,99	deleterious	-2,61	low_impact	0,82	neutral	0,67	neutral	0,58	deleterious	2,72	20,9	0,5	0,6	disease	0,52	neutral	0,35	neutral	0,29	neutral	0,36	3	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,7	low_impact	-3,52	medium_impact	0,06	medium_impact	-0,34	0,78	0,85	30,84	46,13	N	0,35	N	0,66	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8141	8141	G	C	MI.6373	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	556	186	A	P	Gct/Cct	-5,7	0	0	probably_damaging	1	neutral	0,21	neutral	1,79	neutral	-0,57	neutral	-2,27	low_impact	0,81	damaging	0,57	neutral	0,36	deleterious	2,9	21,9	0,13	0,4	neutral	0,3	disease	0,65	disease	0,53	neutral	0,24	5	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,75	low_impact	-3,52	medium_impact	-0,11	medium_impact	-0,35	0,81	0,85	25,55	33	N	0,29	N	0,8	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8141	8141	G	T	MI.6374	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	556	186	A	S	Gct/Tct	-5,7	0	0	probably_damaging	1	neutral	0,44	neutral	1,75	neutral	-1,98	neutral	-0,27	neutral_impact	0,15	neutral	0,73	neutral	0,96	deleterious	2,09	16,77	0,34	0,5	neutral	0,41	neutral	0,2	neutral	0,22	neutral	0,37	3	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,69	low_impact	-3,52	medium_impact	0,15	medium_impact	-0,97	0,77	0,85	25,55	33	N	0,41	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8141	8141	G	A	MI.6375	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	556	186	A	T	Gct/Act	-5,7	0	0	probably_damaging	1	neutral	0,41	neutral	1,76	neutral	-2,04	neutral	0,42	low_impact	0,95	neutral	0,75	neutral	0,79	deleterious	1,9	15,59	0,46	0,55	disease	0,57	neutral	0,18	neutral	0,23	neutral	0,37	3	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,69	low_impact	-3,52	medium_impact	0,12	medium_impact	-0,22	0,62	0,8	25,55	33	N	0,43	N	0,42	polymorphism	1	0,01	.	.	.	.	.	.	COSM1169174	.	.	.	.	.	.	.	.
chrM	8142	8142	C	T	MI.6376	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	557	186	A	V	gCt/gTt	-0,86	0	0	probably_damaging	1	neutral	0,52	neutral	1,79	neutral	-0,6	neutral	-0,28	neutral_impact	0,5	neutral	0,81	neutral	0,69	deleterious	2,36	18,57	0,3	0,45	neutral	0,39	neutral	0,27	neutral	0,28	neutral	0,45	1	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,67	low_impact	-3,52	medium_impact	0,22	medium_impact	-0,64	0,7	0,85	25,55	33	N	0,3	N	0,8	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8142	8142	C	G	MI.6377	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	557	186	A	G	gCt/gGt	-0,86	0	0	probably_damaging	1	neutral	0,33	neutral	1,71	deleterious	-3,6	neutral	-2,46	medium_impact	2,27	neutral	0,65	neutral	0,67	deleterious	4,13	23,8	0,22	0,45	disease	0,78	neutral	0,3	disease	0,52	disease	0,64	3	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,75	low_impact	-3,52	medium_impact	0,04	medium_impact	1,02	0,8	0,85	25,55	33	N	0,35	N	0,42	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8142	8142	C	A	MI.6378	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	557	186	A	D	gCt/gAt	-0,86	0	0	probably_damaging	1	neutral	0,21	neutral	1,7	deleterious	-3,65	deleterious	-2,54	medium_impact	3,17	damaging	0,58	neutral	0,3	deleterious	4,58	24,4	0,11	0,4	disease	0,86	disease	0,6	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,83	low_impact	-3,52	medium_impact	-0,11	medium_impact	1,87	0,7	0,85	25,55	33	N	0,3	N	0,7	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8144	8144	A	T	MI.6379	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	559	187	T	S	Aca/Tca	-20	0	0	possibly_damaging	0,5	neutral	0,87	neutral	1,97	neutral	-0,93	neutral	-0,38	neutral_impact	0,16	neutral	0,75	neutral	0,8	deleterious	0,47	7,23	0,63	0,7	neutral	0,45	neutral	0,11	neutral	0,43	neutral	0,3	4	neutral	0,41	deleterious	0,69	neutral	-3	neutral	0,39	medium_impact	-0,72	medium_impact	0,66	medium_impact	-0,96	0,68	0,85	59,47	14,31	N	0,29	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8827	8827	A	G	MI.638	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	301	101	N	D	Aac/Gac	-0,8	0,02	0	probably_damaging	0,99	deleterious	0	neutral	4,32	neutral	-1,63	deleterious	-4,42	high_impact	3,84	neutral	0,66	neutral	0,49	deleterious	3,79	23,4	0,51	0,65	neutral	0,45	disease	0,69	disease	0,76	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,73	low_impact	-2,65	low_impact	-1,4	high_impact	2,19	0,65	0,9	49,56	8,63	N	0,45	N	0,97	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8144	8144	A	G	MI.6380	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	559	187	T	A	Aca/Gca	-20	0	0	benign	0,34	neutral	0,85	neutral	1,93	neutral	-1,35	neutral	-1,18	medium_impact	2,04	neutral	0,77	neutral	0,8	deleterious	0,56	7,89	0,58	0,65	disease	0,5	neutral	0,24	disease	0,59	neutral	0,42	2	neutral	0,22	deleterious	0,76	neutral	-3	neutral	0,33	medium_impact	-0,45	medium_impact	0,62	medium_impact	0,81	0,34	0,8	59,47	14,31	N	0,28	N	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8144	8144	A	C	MI.6381	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	559	187	T	P	Aca/Cca	-20	0	0	possibly_damaging	0,85	neutral	0,36	neutral	1,91	neutral	-2,39	neutral	-2,3	low_impact	1,29	neutral	0,7	neutral	0,72	deleterious	2,45	19,11	0,25	0,45	disease	0,64	disease	0,7	neutral	0,5	neutral	0,34	3	neutral	0,86	neutral	0,26	neutral	-3	deleterious	0,78	low_impact	-1,42	medium_impact	0,07	medium_impact	0,1	0,53	0,8	59,47	14,31	N	0,29	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8145	8145	C	T	MI.6382	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	560	187	T	M	aCa/aTa	-0,17	0	0	benign	0,16	neutral	0,16	neutral	1,88	deleterious	-3,68	neutral	-2,29	neutral_impact	0,72	neutral	0,95	neutral	0,78	neutral	1,03	10,84	0,34	0,5	disease	0,77	neutral	0,33	disease	0,52	disease	0,65	3	neutral	0,81	deleterious	0,5	neutral	-6	neutral	0,24	medium_impact	-0,05	medium_impact	-0,19	medium_impact	-0,43	0,48	0,8	59,47	14,31	N	0,41	N	0,27	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8145	8145	C	A	MI.6383	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	560	187	T	K	aCa/aAa	-0,17	0	0	possibly_damaging	0,54	neutral	0,95	neutral	1,94	neutral	-0,39	neutral	-2,41	neutral_impact	0,66	neutral	0,65	neutral	0,4	deleterious	3,07	22,4	0,38	0,5	neutral	0,34	neutral	0,47	disease	0,54	neutral	0,38	2	neutral	0,5	deleterious	0,71	neutral	-3	deleterious	0,5	medium_impact	-0,79	medium_impact	0,91	medium_impact	-0,49	0,72	0,85	59,47	14,31	N	0,24	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8147	8147	C	G	MI.6384	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	562	188	R	G	Cga/Gga	-8,7	0	0	probably_damaging	1	neutral	0,35	neutral	1,76	neutral	-2,78	deleterious	-5,41	medium_impact	3,17	damaging	0,35	damaging	0,24	deleterious	4,4	24,1	0,4	0,5	disease	0,81	disease	0,82	disease	0,75	disease	0,67	3	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,82	low_impact	-3,52	medium_impact	0,06	medium_impact	1,87	0,3	0,8	68,72	19,82	P	0,53	P	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8147	8147	C	T	MI.6385	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	562	188	R	W	Cga/Tga	-8,7	0	0	probably_damaging	1	neutral	0,18	neutral	1,74	deleterious	-5,99	deleterious	-5,58	high_impact	4,07	damaging	0,45	damaging	0,11	deleterious	5,36	25,9	0,42	0,55	disease	0,97	disease	0,88	disease	0,75	disease	0,63	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	-0,16	high_impact	2,71	0,68	0,85	68,72	19,82	N	0,33	N	1	polymorphism	0,99	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8148	8148	G	C	MI.6386	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	563	188	R	P	cGa/cCa	2,37	0,01	0	probably_damaging	1	neutral	0,22	neutral	1,76	deleterious	-3,38	deleterious	-5,36	medium_impact	3,17	damaging	0,34	damaging	0,16	deleterious	4,37	24,1	0,2	0,45	disease	0,86	disease	0,9	disease	0,72	disease	0,63	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,89	low_impact	-3,52	medium_impact	-0,1	medium_impact	1,87	0,28	0,8	68,72	19,82	P	0,54	P	1	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8148	8148	G	A	MI.6387	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	563	188	R	Q	cGa/cAa	2,37	0,01	0	probably_damaging	1	neutral	0,31	neutral	1,81	neutral	-0,71	deleterious	-2,68	medium_impact	2,35	damaging	0,45	damaging	0,2	deleterious	4,67	24,5	0,58	0,65	disease	0,68	disease	0,84	disease	0,67	disease	0,55	1	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,81	low_impact	-3,52	medium_impact	0,01	medium_impact	1,1	0,86	0,9	68,72	19,82	N	0,38	N	1	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8148	8148	G	T	MI.6388	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	563	188	R	L	cGa/cTa	2,37	0,01	0	probably_damaging	1	neutral	0,66	neutral	1,81	neutral	-2,84	deleterious	-5,13	medium_impact	2,71	damaging	0,39	neutral	0,31	deleterious	4,41	24,1	0,4	0,5	disease	0,81	disease	0,91	disease	0,72	disease	0,6	2	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,86	low_impact	-3,52	medium_impact	0,36	medium_impact	1,44	0,25	0,8	68,72	19,82	N	0,51	P	1	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8150	8150	C	T	MI.6389	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	565	189	P	S	Ccg/Tcg	-7,09	0	0	probably_damaging	1	neutral	0,75	neutral	1,74	neutral	-1,64	deleterious	-6,38	medium_impact	2,32	damaging	0,26	damaging	0,04	deleterious	4,01	23,6	0,5	0,6	neutral	0,33	disease	0,62	neutral	0,4	neutral	0,16	7	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,73	low_impact	-3,52	medium_impact	0,47	medium_impact	1,07	0,25	0,8	68,28	19,3	N	0,48	N	0,94	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8827	8827	A	T	MI.639	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	301	101	N	Y	Aac/Tac	-0,8	0,02	0	probably_damaging	1	deleterious	0	neutral	4,32	neutral	-1,98	deleterious	-7,09	high_impact	3,84	damaging	0,59	neutral	0,36	deleterious	3,63	23,2	0,25	0,65	disease	0,83	disease	0,8	disease	0,72	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,6	low_impact	-1,4	high_impact	2,19	0,51	0,9	49,56	8,63	N	0,32	N	1	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8150	8150	C	A	MI.6390	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	565	189	P	T	Ccg/Acg	-7,09	0	0	probably_damaging	1	neutral	0,61	neutral	1,76	neutral	-1,03	deleterious	-6,3	low_impact	1,89	damaging	0,19	damaging	0,03	deleterious	3,76	23,3	0,39	0,5	neutral	0,28	disease	0,68	neutral	0,39	neutral	0,16	7	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,71	low_impact	-3,52	medium_impact	0,31	medium_impact	0,67	0,8	0,85	68,28	19,3	P	0,54	P	0,96	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8150	8150	C	G	MI.6391	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	565	189	P	A	Ccg/Gcg	-7,09	0	0	probably_damaging	1	neutral	0,76	neutral	1,78	neutral	-1,4	deleterious	-6,4	medium_impact	2,46	damaging	0,25	damaging	0,14	deleterious	3,16	22,6	0,42	0,55	neutral	0,47	disease	0,53	neutral	0,44	neutral	0,15	7	deleterious	0,99	neutral	0,38	deleterious	1	deleterious	0,73	low_impact	-3,52	medium_impact	0,48	medium_impact	1,2	0,79	0,85	68,28	19,3	P	0,64	P	0,9	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8151	8151	C	G	MI.6392	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	566	189	P	R	cCg/cGg	5,6	1	0	probably_damaging	1	neutral	0,63	neutral	1,71	neutral	-2,31	deleterious	-7,53	high_impact	3,56	damaging	0,14	damaging	0,02	deleterious	3,68	23,3	0,41	0,5	disease	0,59	disease	0,79	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,8	low_impact	-3,52	medium_impact	0,33	high_impact	2,23	0,72	0,85	68,28	19,3	P	0,77	P	0,85	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8151	8151	C	T	MI.6393	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	566	189	P	L	cCg/cTg	5,6	1	0	probably_damaging	1	neutral	0,8	neutral	1,77	neutral	-2,48	deleterious	-8,29	medium_impact	2,02	damaging	0,21	damaging	0,03	deleterious	4,42	24,2	0,52	0,6	disease	0,64	disease	0,77	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,78	low_impact	-3,52	medium_impact	0,54	medium_impact	0,79	0,73	0,85	68,28	19,3	P	0,71	P	0,92	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8151	8151	C	A	MI.6394	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	566	189	P	Q	cCg/cAg	5,6	1	0	probably_damaging	1	neutral	0,53	neutral	1,7	neutral	-1,8	deleterious	-6,58	high_impact	3,56	damaging	0,15	damaging	0,03	deleterious	4,32	24	0,32	0,5	disease	0,56	disease	0,77	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,77	low_impact	-3,52	medium_impact	0,23	high_impact	2,23	0,54	0,8	68,28	19,3	P	0,83	P	0,88	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8153	8153	G	T	MI.6395	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	568	190	G	W	Ggg/Tgg	-3,4	0	0	probably_damaging	1	neutral	0,18	neutral	-0,71	deleterious	-12,45	deleterious	-7,75	high_impact	4,63	damaging	0,17	damaging	0,01	deleterious	4,61	24,4	0,17	0,45	disease	0,99	disease	0,86	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	-0,16	high_impact	3,24	0,34	0,8	68,72	19,86	P	0,62	P	0,98	disease_causing	0,98	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8153	8153	G	C	MI.6396	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	568	190	G	R	Ggg/Cgg	-3,4	0	0	probably_damaging	1	neutral	0,35	neutral	-0,69	deleterious	-8,78	deleterious	-7,73	high_impact	3,73	damaging	0,18	damaging	0,01	deleterious	4,17	23,8	0,18	0,45	disease	0,93	disease	0,84	disease	0,83	disease	0,66	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	0,06	high_impact	2,39	0,72	0,85	68,72	19,86	P	0,68	P	1	disease_causing	0,97	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8154	8154	G	C	MI.6397	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	569	190	G	A	gGg/gCg	9,29	1	0	probably_damaging	1	neutral	0,51	neutral	-0,67	deleterious	-7,53	deleterious	-5,78	high_impact	3,94	damaging	0,2	damaging	0,09	deleterious	3,32	22,9	0,19	0,45	disease	0,58	disease	0,67	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	0,21	high_impact	2,59	0,44	0,8	68,72	19,86	P	0,85	P	0,85	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8154	8154	G	A	MI.6398	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	569	190	G	E	gGg/gAg	9,29	1	0	probably_damaging	1	neutral	0,27	neutral	-0,7	deleterious	-9,69	deleterious	-7,72	high_impact	4,08	damaging	0,16	damaging	0,01	deleterious	4,07	23,7	0,21	0,45	disease	0,85	disease	0,84	disease	0,82	disease	0,67	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	-0,03	high_impact	2,72	0,49	0,8	68,72	19,86	P	0,84	P	1	disease_causing	1	0,26	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	8154	8154	G	T	MI.6399	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	569	190	G	V	gGg/gTg	9,29	1	0	probably_damaging	1	neutral	0,51	neutral	-0,7	deleterious	-9,39	deleterious	-8,71	high_impact	4,63	damaging	0,13	damaging	0,01	deleterious	4,02	23,6	0,16	0,45	disease	0,93	disease	0,85	disease	0,76	disease	0,61	2	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	0,21	high_impact	3,24	0,46	0,8	68,72	19,86	P	0,74	P	1	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8554	8554	A	T	MI.64	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	28	10	I	F	Att/Ttt	-0,33	0	0	benign	0,02	neutral	0,09	neutral	4,68	neutral	-1,13	neutral	-1,33	low_impact	1,08	neutral	0,9	neutral	0,51	deleterious	0,45	7,01	0,39	0,65	disease	0,67	disease	0,55	neutral	0,36	disease	0,51	0	neutral	0,91	deleterious	0,54	neutral	-6	neutral	0,22	medium_impact	0,85	medium_impact	-0,28	medium_impact	-0,17	0,39	0,9	27,43	16,7	N	0,41	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8828	8828	A	G	MI.640	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	302	101	N	S	aAc/aGc	6,84	1	0	probably_damaging	0,99	neutral	0,28	neutral	4,36	neutral	-0,62	deleterious	-4,35	low_impact	1	neutral	0,64	neutral	0,61	deleterious	2,91	21,9	0,6	0,7	disease	0,56	disease	0,52	disease	0,53	neutral	0,39	2	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,73	low_impact	-2,65	medium_impact	0,06	medium_impact	-0,24	0,54	0,9	49,56	8,63	P	0,51	P	0,91	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8156	8156	G	C	MI.6400	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	571	191	V	L	Gta/Cta	-11,7	0	0	benign	0,34	neutral	0,8	neutral	1,89	neutral	-1,38	neutral	-0,49	neutral_impact	0,39	neutral	0,75	neutral	0,97	neutral	-0,16	1,33	0,47	0,55	neutral	0,45	neutral	0,09	neutral	0,19	neutral	0,28	4	neutral	0,22	deleterious	0,73	neutral	-6	neutral	0,35	medium_impact	-0,45	medium_impact	0,54	medium_impact	-0,74	0,56	0,8	29,52	67,21	N	0,44	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8156	8156	G	T	MI.6401	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	571	191	V	L	Gta/Tta	-11,7	0	0	benign	0,34	neutral	0,8	neutral	1,89	neutral	-1,38	neutral	-0,49	neutral_impact	0,39	neutral	0,75	neutral	0,97	deleterious	-0,04	2,25	0,47	0,55	neutral	0,45	neutral	0,09	neutral	0,19	neutral	0,28	4	neutral	0,22	deleterious	0,73	neutral	-6	neutral	0,35	medium_impact	-0,45	medium_impact	0,54	medium_impact	-0,74	0,56	0,8	29,52	67,21	N	0,43	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8156	8156	G	A	MI.6402	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	571	191	V	M	Gta/Ata	-11,7	0	0	possibly_damaging	0,9	neutral	0,25	neutral	1,75	neutral	-2,28	neutral	-1,27	medium_impact	2,09	damaging	0,6	neutral	0,61	deleterious	3,67	23,2	0,38	0,5	disease	0,53	neutral	0,42	neutral	0,46	neutral	0,4	2	neutral	0,92	neutral	0,18	NA	0	deleterious	0,65	low_impact	-1,61	medium_impact	-0,06	medium_impact	0,85	0,79	0,85	29,52	67,21	N	0,41	N	0,55	polymorphism	1	0,04	.	.	.	.	.	.	COSM1319391	.	.	.	.	.	.	.	.
chrM	8157	8157	T	A	MI.6403	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	572	191	V	E	gTa/gAa	-2,24	0	0	possibly_damaging	0,67	neutral	0,32	neutral	1,78	neutral	-1,13	deleterious	-4,94	medium_impact	2,74	damaging	0,5	neutral	0,42	deleterious	4,61	24,5	0,22	0,45	disease	0,55	disease	0,79	disease	0,71	disease	0,72	4	neutral	0,74	neutral	0,33	NA	0	deleterious	0,65	low_impact	-1,01	medium_impact	0,02	medium_impact	1,46	0,54	0,8	29,52	67,21	N	0,35	N	0,96	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8157	8157	T	G	MI.6404	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	572	191	V	G	gTa/gGa	-2,24	0	0	possibly_damaging	0,46	neutral	0,47	neutral	1,74	neutral	-2,55	deleterious	-5,91	high_impact	3,63	damaging	0,52	neutral	0,54	deleterious	2,41	18,87	0,24	0,45	disease	0,81	disease	0,69	disease	0,61	disease	0,67	3	neutral	0,5	deleterious	0,51	deleterious	1	deleterious	0,57	medium_impact	-0,66	medium_impact	0,18	high_impact	2,3	0,36	0,8	29,52	67,21	N	0,31	N	0,94	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8157	8157	T	C	MI.6405	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	572	191	V	A	gTa/gCa	-2,24	0	0	benign	0,01	neutral	0,56	neutral	1,79	neutral	-0,84	deleterious	-3,03	medium_impact	3,08	neutral	0,66	neutral	0,66	deleterious	1,82	15,08	0,37	0,5	disease	0,62	neutral	0,41	disease	0,6	disease	0,65	3	neutral	0,42	deleterious	0,78	neutral	-3	neutral	0,2	medium_impact	1,14	medium_impact	0,26	medium_impact	1,78	0,3	0,8	29,52	67,21	N	0,33	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8159	8159	T	G	MI.6406	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	574	192	Y	D	Tac/Gac	-5,01	0	0	probably_damaging	1	neutral	0,18	neutral	1,45	deleterious	-7,62	deleterious	-6,73	high_impact	3,58	damaging	0,59	neutral	0,33	deleterious	4,06	23,7	0,15	0,4	disease	0,96	disease	0,78	disease	0,8	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,16	high_impact	2,25	0,27	0,8	68,72	15,57	N	0,34	N	0,91	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8159	8159	T	C	MI.6407	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	574	192	Y	H	Tac/Cac	-5,01	0	0	probably_damaging	1	neutral	0,5	neutral	1,56	deleterious	-5,84	deleterious	-4	medium_impact	2,89	neutral	0,65	neutral	0,37	deleterious	3,7	23,3	0,31	0,45	disease	0,9	disease	0,52	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,86	low_impact	-3,52	medium_impact	0,21	medium_impact	1,6	0,42	0,8	68,72	15,57	N	0,32	N	0,7	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8159	8159	T	A	MI.6408	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	574	192	Y	N	Tac/Aac	-5,01	0	0	probably_damaging	1	neutral	0,3	neutral	1,46	deleterious	-6,66	deleterious	-6,39	medium_impact	2,89	neutral	0,63	neutral	0,48	deleterious	4,14	23,8	0,21	0,45	disease	0,93	disease	0,77	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,88	low_impact	-3,52	medium_impact	0	medium_impact	1,6	0,29	0,8	68,72	15,57	N	0,28	N	0,88	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8160	8160	A	C	MI.6409	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	575	192	Y	S	tAc/tCc	5,83	0,97	0	probably_damaging	1	neutral	0,39	neutral	1,47	deleterious	-5,67	deleterious	-5,64	medium_impact	2,38	neutral	0,63	neutral	0,48	deleterious	3,78	23,4	0,18	0,45	disease	0,55	disease	0,67	disease	0,68	disease	0,61	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,83	low_impact	-3,52	medium_impact	0,1	medium_impact	1,13	0,33	0,8	68,72	15,57	N	0,49	N	0,86	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8828	8828	A	T	MI.641	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	302	101	N	I	aAc/aTc	6,84	1	0	probably_damaging	1	neutral	0,09	neutral	4,37	neutral	-0,32	deleterious	-8,01	medium_impact	2,48	neutral	0,63	neutral	0,58	deleterious	3,77	23,4	0,26	0,65	disease	0,62	disease	0,87	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	-0,28	medium_impact	1,03	0,51	0,9	49,56	8,63	P	0,49	N	1	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8160	8160	A	G	MI.6410	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	575	192	Y	C	tAc/tGc	5,83	0,97	0	probably_damaging	1	neutral	0,17	neutral	1,45	deleterious	-7,28	deleterious	-5,82	high_impact	3,58	neutral	0,66	neutral	0,36	deleterious	3,55	23,1	0,26	0,45	disease	0,96	disease	0,83	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	-0,18	high_impact	2,25	0,29	0,8	68,72	15,57	N	0,5	N	0,87	polymorphism	1	0,21	.	.	.	.	.	.	COSM218998	.	.	.	.	.	.	.	.
chrM	8160	8160	A	T	MI.6411	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	575	192	Y	F	tAc/tTc	5,83	0,97	0	probably_damaging	1	neutral	0,81	neutral	2,01	neutral	-1,45	neutral	0,73	neutral_impact	-0,5	neutral	0,68	neutral	0,93	deleterious	0,71	8,9	0,27	0,45	neutral	0,25	neutral	0,07	neutral	0,25	neutral	0,21	6	deleterious	1	neutral	0,41	neutral	-2	deleterious	0,68	low_impact	-3,52	medium_impact	0,55	low_impact	-1,57	0,63	0,8	68,72	15,57	P	0,54	P	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8162	8162	T	A	MI.6412	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	577	193	Y	N	Tac/Aac	-3,63	0	0	probably_damaging	1	neutral	0,29	neutral	1,83	neutral	-2,64	deleterious	-8,39	high_impact	3,78	damaging	0,36	damaging	0,02	deleterious	4,36	24,1	0,33	0,5	neutral	0,45	disease	0,87	disease	0,76	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-3,52	medium_impact	-0,01	high_impact	2,44	0,28	0,8	68,72	19,3	N	0,48	N	0,99	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8162	8162	T	G	MI.6413	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	577	193	Y	D	Tac/Gac	-3,63	0	0	probably_damaging	1	neutral	0,19	neutral	1,82	deleterious	-3,15	deleterious	-9,25	high_impact	3,78	damaging	0,29	damaging	0,03	deleterious	4,11	23,8	0,32	0,5	disease	0,63	disease	0,88	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	-0,14	high_impact	2,44	0,33	0,8	68,72	19,3	P	0,59	P	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8162	8162	T	C	MI.6414	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	577	193	Y	H	Tac/Cac	-3,63	0	0	probably_damaging	1	neutral	0,5	neutral	1,82	neutral	-2,96	deleterious	-4,73	medium_impact	3,15	damaging	0,38	damaging	0,02	deleterious	3,77	23,4	0,46	0,55	disease	0,75	disease	0,76	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,85	low_impact	-3,52	medium_impact	0,21	medium_impact	1,85	0,35	0,8	68,72	19,3	N	0,42	N	0,94	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8163	8163	A	C	MI.6415	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	578	193	Y	S	tAc/tCc	7,44	1	0	probably_damaging	1	neutral	0,39	neutral	1,86	neutral	-1,7	deleterious	-8,28	medium_impact	3,15	damaging	0,33	damaging	0,04	deleterious	3,86	23,5	0,26	0,45	neutral	0,37	disease	0,86	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,81	low_impact	-3,52	medium_impact	0,1	medium_impact	1,85	0,28	0,8	68,72	19,3	P	0,61	P	0,99	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8163	8163	A	G	MI.6416	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	578	193	Y	C	tAc/tGc	7,44	1	0	probably_damaging	1	neutral	0,17	neutral	1,82	deleterious	-3,4	deleterious	-8,28	medium_impact	3,23	damaging	0,28	damaging	0,02	deleterious	3,71	23,3	0,31	0,45	disease	0,86	disease	0,9	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,88	low_impact	-3,52	medium_impact	-0,18	medium_impact	1,92	0,19	0,8	68,72	19,3	P	0,79	P	0,96	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8163	8163	A	T	MI.6417	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	578	193	Y	F	tAc/tTc	7,44	1	0	probably_damaging	1	neutral	0,68	neutral	1,96	neutral	-0,31	deleterious	-3,15	low_impact	0,95	damaging	0,57	neutral	0,43	deleterious	2,44	19,1	0,41	0,5	neutral	0,47	neutral	0,28	neutral	0,47	neutral	0,39	2	deleterious	1	neutral	0,34	neutral	-2	deleterious	0,75	low_impact	-3,52	medium_impact	0,39	medium_impact	-0,22	0,42	0,8	68,72	19,3	P	0,54	P	0,87	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8165	8165	G	C	MI.6418	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	580	194	G	R	Ggt/Cgt	-5,24	0	0	probably_damaging	1	neutral	0,36	neutral	1,65	deleterious	-4,81	deleterious	-7,74	high_impact	4,63	damaging	0,19	damaging	0,01	deleterious	4,14	23,8	0,12	0,4	disease	0,84	disease	0,86	disease	0,85	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	0,07	high_impact	3,24	0,7	0,85	68,72	19,86	P	0,69	P	1	polymorphism	0,98	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8165	8165	G	A	MI.6419	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	580	194	G	S	Ggt/Agt	-5,24	0	0	probably_damaging	1	neutral	0,42	neutral	1,66	deleterious	-3,86	deleterious	-5,8	high_impact	4,63	damaging	0,16	damaging	0,01	deleterious	4,41	24,1	0,27	0,45	disease	0,77	disease	0,86	disease	0,78	disease	0,67	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,13	high_impact	3,24	0,73	0,85	68,72	19,86	P	0,76	P	0,98	polymorphism	0,99	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8828	8828	A	C	MI.642	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	302	101	N	T	aAc/aCc	6,84	1	0	probably_damaging	0,99	neutral	1	neutral	4,8	neutral	2,54	deleterious	-5,26	neutral_impact	0,73	neutral	0,62	neutral	0,52	deleterious	3,26	22,8	0,38	0,65	neutral	0,46	neutral	0,36	disease	0,53	neutral	0,42	2	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,69	low_impact	-2,65	high_impact	1,98	medium_impact	-0,47	0,58	0,9	49,56	8,63	N	0,44	N	0,96	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8165	8165	G	T	MI.6420	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	580	194	G	C	Ggt/Tgt	-5,24	0	0	probably_damaging	1	neutral	0,22	neutral	1,64	deleterious	-5,49	deleterious	-8,71	high_impact	4,63	damaging	0,19	damaging	0,01	deleterious	4,31	24	0,13	0,4	disease	0,63	disease	0,91	disease	0,8	disease	0,72	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	-0,1	high_impact	3,24	0,71	0,85	68,72	19,86	P	0,62	P	0,99	polymorphism	0,96	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8166	8166	G	A	MI.6421	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	581	194	G	D	gGt/gAt	4,21	1	0	probably_damaging	1	neutral	0,21	neutral	1,63	deleterious	-5,61	deleterious	-6,77	high_impact	4,63	damaging	0,21	damaging	0,01	deleterious	3,91	23,5	0,13	0,4	disease	0,89	disease	0,88	disease	0,84	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	-0,11	high_impact	3,24	0,57	0,8	68,72	19,86	P	0,85	P	0,99	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8166	8166	G	C	MI.6422	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	581	194	G	A	gGt/gCt	4,21	1	0	probably_damaging	1	neutral	0,49	neutral	1,68	deleterious	-3,08	deleterious	-5,8	high_impact	4,28	damaging	0,22	damaging	0,07	deleterious	3,3	22,9	0,25	0,45	disease	0,52	disease	0,74	disease	0,79	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	0,2	high_impact	2,91	0,8	0,85	68,72	19,86	P	0,85	P	0,85	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8166	8166	G	T	MI.6423	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	581	194	G	V	gGt/gTt	4,21	1	0	probably_damaging	1	neutral	0,52	neutral	1,72	neutral	-2,08	deleterious	-8,71	high_impact	4,63	damaging	0,15	damaging	0,01	deleterious	3,95	23,6	0,15	0,4	neutral	0,49	disease	0,88	disease	0,81	disease	0,72	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	0,22	high_impact	3,24	0,65	0,8	68,72	19,86	P	0,78	P	1	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8168	8168	C	G	MI.6424	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	583	195	Q	E	Caa/Gaa	-15,16	0	0	probably_damaging	0,98	neutral	0,27	neutral	1,81	neutral	-2,06	deleterious	-2,9	high_impact	3,85	damaging	0,17	damaging	0,04	deleterious	3,26	22,8	0,45	0,55	disease	0,62	disease	0,76	disease	0,77	disease	0,69	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-2,3	medium_impact	-0,03	high_impact	2,5	0,7	0,85	67,4	20,25	P	0,66	P	0,85	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8168	8168	C	A	MI.6425	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	583	195	Q	K	Caa/Aaa	-15,16	0	0	probably_damaging	0,99	neutral	0,29	neutral	1,83	neutral	-1,43	deleterious	-3,86	medium_impact	3,12	damaging	0,17	damaging	0,01	deleterious	4,1	23,7	0,45	0,55	neutral	0,46	disease	0,86	disease	0,76	disease	0,7	4	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,85	low_impact	-2,58	medium_impact	-0,01	medium_impact	1,82	0,58	0,8	67,4	20,25	P	0,68	P	0,97	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8169	8169	A	C	MI.6426	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	584	195	Q	P	cAa/cCa	4,44	1	0	probably_damaging	1	neutral	0,21	neutral	1,8	deleterious	-4,05	deleterious	-5,79	high_impact	3,99	damaging	0,16	damaging	0,04	deleterious	3,52	23,1	0,21	0,45	disease	0,85	disease	0,86	disease	0,75	disease	0,62	2	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	-0,11	high_impact	2,64	0,5	0,8	67,4	20,25	P	0,85	P	0,95	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8169	8169	A	T	MI.6427	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	584	195	Q	L	cAa/cTa	4,44	1	0	probably_damaging	0,99	neutral	0,65	neutral	1,94	neutral	-1,76	deleterious	-6,76	high_impact	3,99	damaging	0,14	damaging	0,03	deleterious	4	23,6	0,29	0,45	disease	0,73	disease	0,87	disease	0,75	disease	0,68	4	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,88	low_impact	-2,58	medium_impact	0,35	high_impact	2,64	0,23	0,8	67,4	20,25	P	0,83	P	0,97	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8169	8169	A	G	MI.6428	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	584	195	Q	R	cAa/cGa	4,44	1	0	probably_damaging	1	neutral	0,34	neutral	1,85	neutral	-1,53	deleterious	-3,86	high_impact	3,73	damaging	0,16	damaging	0,03	deleterious	3,65	23,2	0,49	0,55	neutral	0,44	disease	0,82	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	0,05	high_impact	2,39	0,58	0,8	67,4	20,25	P	0,87	P	0,95	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8170	8170	A	T	MI.6429	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	585	195	Q	H	caA/caT	8,59	1	0	probably_damaging	1	neutral	0,54	neutral	1,8	deleterious	-3,62	deleterious	-4,83	high_impact	4,2	damaging	0,13	damaging	0,03	deleterious	3,74	23,3	0,44	0,55	disease	0,7	disease	0,77	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,24	high_impact	2,83	0,68	0,85	67,4	20,25	P	0,87	P	0,86	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8829	8829	C	G	MI.643	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	303	101	N	K	aaC/aaG	8,69	1	0,06	probably_damaging	0,99	deleterious	0	neutral	4,35	neutral	-0,73	deleterious	-5,1	high_impact	3,84	damaging	0,57	neutral	0,4	deleterious	3,97	23,6	0,47	0,65	disease	0,53	disease	0,79	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,65	low_impact	-1,4	high_impact	2,19	0,7	0,9	49,56	8,63	P	0,5	N	1	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8170	8170	A	C	MI.6430	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	585	195	Q	H	caA/caC	8,59	1	0	probably_damaging	1	neutral	0,54	neutral	1,8	deleterious	-3,62	deleterious	-4,83	high_impact	4,2	damaging	0,13	damaging	0,03	deleterious	3,69	23,3	0,44	0,55	disease	0,7	disease	0,77	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,24	high_impact	2,83	0,68	0,85	67,4	20,25	P	0,86	P	0,86	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8171	8171	T	A	MI.6431	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	586	196	C	S	Tgc/Agc	-0,17	0,33	0	probably_damaging	1	neutral	0,55	neutral	0,13	deleterious	-6,59	deleterious	-9,6	high_impact	3,92	damaging	0,11	damaging	0,02	deleterious	3,87	23,5	0,25	0,45	disease	0,66	disease	0,9	disease	0,87	disease	0,74	5	deleterious	0,99	neutral	0,28	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	0,25	high_impact	2,57	0,53	0,8	67,84	19,95	P	0,69	P	0,84	disease_causing	0,99	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8171	8171	T	G	MI.6432	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	586	196	C	G	Tgc/Ggc	-0,17	0,33	0	probably_damaging	1	neutral	0,46	neutral	0,12	deleterious	-6,91	deleterious	-11,52	high_impact	4,61	damaging	0,1	damaging	0,03	deleterious	3,51	23,1	0,2	0,45	disease	0,87	disease	0,89	disease	0,88	disease	0,64	3	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	0,17	high_impact	3,22	0,44	0,8	67,84	19,95	P	0,67	P	0,96	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8171	8171	T	C	MI.6433	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	586	196	C	R	Tgc/Cgc	-0,17	0,33	0	probably_damaging	1	neutral	0,37	neutral	0,1	deleterious	-8,14	deleterious	-11,52	high_impact	4,26	damaging	0,13	damaging	0,02	deleterious	3,73	23,3	0,22	0,45	disease	0,88	disease	0,91	disease	0,92	disease	0,64	3	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,93	low_impact	-3,52	medium_impact	0,08	high_impact	2,89	0,33	0,8	67,84	19,95	P	0,66	P	0,98	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8172	8172	G	A	MI.6434	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	587	196	C	Y	tGc/tAc	7,44	1	0	probably_damaging	1	neutral	1	neutral	0,1	deleterious	-8,61	deleterious	-10,56	high_impact	4,26	damaging	0,13	damaging	0,02	deleterious	3,84	23,4	0,23	0,45	disease	0,89	disease	0,94	disease	0,9	disease	0,66	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,93	low_impact	-3,52	high_impact	1,86	high_impact	2,89	0,5	0,8	67,84	19,95	P	0,67	P	0,97	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8172	8172	G	C	MI.6435	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	587	196	C	S	tGc/tCc	7,44	1	0	probably_damaging	1	neutral	0,55	neutral	0,13	deleterious	-6,59	deleterious	-9,6	high_impact	3,92	damaging	0,11	damaging	0,02	deleterious	3,3	22,9	0,25	0,45	disease	0,66	disease	0,9	disease	0,87	disease	0,74	5	deleterious	0,99	neutral	0,28	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	0,25	high_impact	2,57	0,53	0,8	67,84	19,95	P	0,74	P	0,84	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8172	8172	G	T	MI.6436	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	587	196	C	F	tGc/tTc	7,44	1	0	probably_damaging	1	neutral	0,72	neutral	0,1	deleterious	-8,21	deleterious	-10,56	high_impact	4,61	damaging	0,1	damaging	0,01	deleterious	4,05	23,7	0,19	0,45	disease	0,87	disease	0,95	disease	0,9	disease	0,67	3	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,93	low_impact	-3,52	medium_impact	0,43	high_impact	3,22	0,46	0,8	67,84	19,95	P	0,72	P	0,99	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8173	8173	C	A	MI.6437	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	588	196	C	W	tgC/tgA	7,21	1	0	probably_damaging	1	neutral	0,17	neutral	0,09	deleterious	-10,04	deleterious	-10,56	high_impact	4,61	damaging	0,15	damaging	0,02	deleterious	4,71	24,6	0,16	0,45	disease	0,96	disease	0,92	disease	0,92	disease	0,64	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,93	low_impact	-3,52	medium_impact	-0,18	high_impact	3,22	0,32	0,8	67,84	19,95	P	0,74	P	0,99	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8173	8173	C	G	MI.6438	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	588	196	C	W	tgC/tgG	7,21	1	0	probably_damaging	1	neutral	0,17	neutral	0,09	deleterious	-10,04	deleterious	-10,56	high_impact	4,61	damaging	0,15	damaging	0,02	deleterious	4,48	24,2	0,16	0,45	disease	0,96	disease	0,92	disease	0,92	disease	0,64	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,93	low_impact	-3,52	medium_impact	-0,18	high_impact	3,22	0,32	0,8	67,84	19,95	P	0,74	P	0,99	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8174	8174	T	C	MI.6439	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	589	197	S	P	Tct/Cct	-0,17	0,71	0	probably_damaging	1	neutral	0,2	neutral	1,54	deleterious	-4,38	deleterious	-4,74	high_impact	3,73	damaging	0,17	damaging	0,04	deleterious	4,13	23,8	0,17	0,45	disease	0,87	disease	0,82	disease	0,85	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	-0,13	high_impact	2,39	0,68	0,85	68,72	20,02	P	0,86	P	0,99	disease_causing	0,9	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8829	8829	C	A	MI.644	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	303	101	N	K	aaC/aaA	8,69	1	0,06	probably_damaging	0,99	deleterious	0	neutral	4,35	neutral	-0,73	deleterious	-5,1	high_impact	3,84	damaging	0,57	neutral	0,4	deleterious	4,44	24,2	0,47	0,65	disease	0,53	disease	0,79	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,65	low_impact	-1,4	high_impact	2,19	0,7	0,9	49,56	8,63	P	0,51	P	1	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8174	8174	T	A	MI.6440	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	589	197	S	T	Tct/Act	-0,17	0,71	0	probably_damaging	0,99	neutral	0,38	neutral	1,57	deleterious	-3,19	deleterious	-2,83	medium_impact	2,73	damaging	0,16	damaging	0,03	deleterious	4,02	23,6	0,25	0,45	neutral	0,41	disease	0,78	disease	0,76	disease	0,68	4	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,79	low_impact	-2,58	medium_impact	0,09	medium_impact	1,45	0,78	0,85	68,72	20,02	P	0,84	P	0,53	disease_causing	0,58	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8174	8174	T	G	MI.6441	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	589	197	S	A	Tct/Gct	-0,17	0,71	0	probably_damaging	0,99	neutral	0,5	neutral	1,6	neutral	-2,71	deleterious	-2,83	medium_impact	2,02	damaging	0,2	damaging	0,1	deleterious	3,88	23,5	0,37	0,5	neutral	0,29	disease	0,66	disease	0,76	disease	0,66	3	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,72	low_impact	-2,58	medium_impact	0,21	medium_impact	0,79	0,59	0,8	68,72	20,02	P	0,85	P	0,36	polymorphism	0,71	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8175	8175	C	A	MI.6442	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	590	197	S	Y	tCt/tAt	5,83	1	0	probably_damaging	1	neutral	1	neutral	1,53	deleterious	-5,14	deleterious	-5,51	high_impact	3,73	damaging	0,17	damaging	0,06	deleterious	4,18	23,8	0,17	0,45	disease	0,87	disease	0,89	disease	0,79	disease	0,65	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,88	low_impact	-3,52	high_impact	1,86	high_impact	2,39	0,65	0,8	68,72	20,02	P	0,75	P	1	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8175	8175	C	G	MI.6443	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	590	197	S	C	tCt/tGt	5,83	1	0	probably_damaging	1	neutral	0,23	neutral	1,52	deleterious	-6,12	deleterious	-4,72	high_impact	4,42	damaging	0,2	damaging	0,02	deleterious	3,76	23,3	0,24	0,45	disease	0,91	disease	0,82	disease	0,77	disease	0,64	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,09	high_impact	3,04	0,61	0,8	68,72	20,02	P	0,81	P	0,91	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8175	8175	C	T	MI.6444	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	590	197	S	F	tCt/tTt	5,83	1	0	probably_damaging	1	neutral	0,71	neutral	1,52	deleterious	-5,44	deleterious	-5,58	high_impact	4,07	damaging	0,15	damaging	0,03	deleterious	4,35	24,1	0,16	0,45	disease	0,85	disease	0,89	disease	0,79	disease	0,68	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,42	high_impact	2,71	0,39	0,8	68,72	20,02	P	0,78	P	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8177	8177	G	C	MI.6445	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	592	198	E	Q	Gaa/Caa	-2,01	0	0	probably_damaging	1	neutral	0,63	neutral	1,57	deleterious	-3,26	deleterious	-2,88	medium_impact	3,08	damaging	0,14	damaging	0,04	deleterious	3,55	23,1	0,34	0,5	disease	0,73	disease	0,82	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,87	low_impact	-3,52	medium_impact	0,33	medium_impact	1,78	0,83	0,85	68,72	19,71	P	0,76	P	0,76	polymorphism	0,99	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8177	8177	G	A	MI.6446	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	592	198	E	K	Gaa/Aaa	-2,01	0	0	probably_damaging	1	neutral	0,89	neutral	1,55	deleterious	-3,32	deleterious	-3,84	high_impact	3,68	damaging	0,14	damaging	0,02	deleterious	4,64	24,5	0,32	0,5	disease	0,8	disease	0,92	disease	0,79	disease	0,68	4	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	0,71	high_impact	2,35	0,72	0,85	68,72	19,71	P	0,73	P	0,99	polymorphism	0,97	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8178	8178	A	G	MI.6447	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	593	198	E	G	gAa/gGa	7,21	1	0	probably_damaging	1	neutral	0,49	neutral	1,54	deleterious	-5,07	deleterious	-6,72	high_impact	4,58	damaging	0,1	damaging	0,06	deleterious	4,48	24,2	0,29	0,45	disease	0,88	disease	0,83	disease	0,75	disease	0,62	2	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,2	high_impact	3,19	0,49	0,8	68,72	19,71	P	0,87	P	0,64	disease_causing	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8178	8178	A	C	MI.6448	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	593	198	E	A	gAa/gCa	7,21	1	0	probably_damaging	1	neutral	0,85	neutral	1,56	deleterious	-3,95	deleterious	-5,76	high_impact	4,58	damaging	0,19	damaging	0,11	deleterious	3,91	23,5	0,21	0,45	disease	0,83	disease	0,83	disease	0,74	disease	0,68	4	deleterious	1	neutral	0,43	deleterious	2	deleterious	0,88	low_impact	-3,52	medium_impact	0,62	high_impact	3,19	0,67	0,85	68,72	19,71	P	0,83	P	0,66	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8178	8178	A	T	MI.6449	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	593	198	E	V	gAa/gTa	7,21	1	0	probably_damaging	1	neutral	0,49	neutral	1,55	deleterious	-4,98	deleterious	-6,72	high_impact	4,23	damaging	0,12	damaging	0,03	deleterious	4,47	24,2	0,2	0,45	disease	0,92	disease	0,93	disease	0,79	disease	0,65	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	0,2	high_impact	2,86	0,68	0,85	68,72	19,71	P	0,85	P	0,82	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8830	8830	C	G	MI.645	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	304	102	L	V	Cta/Gta	-3,57	0	0	probably_damaging	0,99	neutral	0,06	neutral	4,17	neutral	-1,26	neutral	-2,01	medium_impact	2,23	neutral	0,86	neutral	0,48	deleterious	3,35	22,9	0,37	0,65	disease	0,53	neutral	0,5	disease	0,56	disease	0,57	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,72	low_impact	-2,65	medium_impact	-0,38	medium_impact	0,81	0,73	0,9	18,14	17,58	N	0,36	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8179	8179	A	T	MI.6450	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	594	198	E	D	gaA/gaT	8,59	1	0	probably_damaging	0,99	neutral	0,59	neutral	1,55	deleterious	-4,12	deleterious	-2,88	high_impact	4,58	damaging	0,19	damaging	0,03	deleterious	4,05	23,7	0,34	0,5	disease	0,57	disease	0,8	disease	0,7	disease	0,67	3	deleterious	0,99	neutral	0,3	deleterious	2	deleterious	0,83	low_impact	-2,58	medium_impact	0,29	high_impact	3,19	0,75	0,85	68,72	19,71	P	0,85	P	0,81	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8179	8179	A	C	MI.6451	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	594	198	E	D	gaA/gaC	8,59	1	0	probably_damaging	0,99	neutral	0,59	neutral	1,55	deleterious	-4,12	deleterious	-2,88	high_impact	4,58	damaging	0,19	damaging	0,03	deleterious	3,9	23,5	0,34	0,5	disease	0,57	disease	0,8	disease	0,7	disease	0,67	3	deleterious	0,99	neutral	0,3	deleterious	2	deleterious	0,83	low_impact	-2,58	medium_impact	0,29	high_impact	3,19	0,75	0,85	68,72	19,71	P	0,84	P	0,81	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8180	8180	A	C	MI.6452	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	595	199	I	L	Atc/Ctc	1,68	1	0	probably_damaging	0,98	neutral	0,81	neutral	2,16	neutral	1,76	neutral	-1,92	low_impact	1,09	damaging	0,13	damaging	0,05	deleterious	3,87	23,5	0,35	0,5	neutral	0,28	disease	0,71	disease	0,59	disease	0,54	1	deleterious	0,98	neutral	0,42	neutral	-2	deleterious	0,69	low_impact	-2,3	medium_impact	0,55	medium_impact	-0,08	0,7	0,85	68,72	19,93	P	0,85	P	0,71	disease_causing	0,69	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8180	8180	A	T	MI.6453	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	595	199	I	F	Atc/Ttc	1,68	1	0	probably_damaging	1	neutral	0,75	neutral	2	neutral	-1,03	deleterious	-3,84	medium_impact	2,25	damaging	0,13	damaging	0,03	deleterious	3,84	23,4	0,37	0,5	neutral	0,25	disease	0,88	disease	0,73	disease	0,67	3	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,78	low_impact	-3,52	medium_impact	0,47	medium_impact	1	0,69	0,85	68,72	19,93	P	0,82	P	0,92	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8180	8180	A	G	MI.6454	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	595	199	I	V	Atc/Gtc	1,68	1	0	probably_damaging	0,95	neutral	0,64	neutral	1,85	neutral	-0,83	neutral	-0,96	medium_impact	2,96	damaging	0,14	damaging	0,07	deleterious	3,11	22,5	0,53	0,6	disease	0,51	disease	0,61	disease	0,66	disease	0,64	3	neutral	0,95	neutral	0,35	deleterious	1	deleterious	0,7	low_impact	-1,91	medium_impact	0,34	medium_impact	1,67	0,58	0,8	68,72	19,93	P	0,84	P	0,54	polymorphism	0,51	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8181	8181	T	A	MI.6455	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	596	199	I	N	aTc/aAc	5,6	1	0	probably_damaging	1	neutral	0,55	neutral	1,79	deleterious	-3,77	deleterious	-6,72	high_impact	4,11	damaging	0,15	damaging	0,02	deleterious	4,84	24,8	0,26	0,45	disease	0,8	disease	0,89	disease	0,74	disease	0,67	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	0,25	high_impact	2,75	0,48	0,8	68,72	19,93	P	0,82	P	0,99	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8181	8181	T	C	MI.6456	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	596	199	I	T	aTc/aCc	5,6	1	0	probably_damaging	1	neutral	0,68	neutral	1,81	neutral	-2,14	deleterious	-4,8	high_impact	4,11	damaging	0,13	damaging	0,02	deleterious	3,67	23,3	0,37	0,5	disease	0,61	disease	0,88	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	0,39	high_impact	2,75	0,52	0,8	68,72	19,93	P	0,81	P	0,96	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8181	8181	T	G	MI.6457	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	596	199	I	S	aTc/aGc	5,6	1	0	probably_damaging	1	neutral	0,87	neutral	1,8	neutral	-2,52	deleterious	-5,76	high_impact	4,11	damaging	0,12	damaging	0,06	deleterious	4,5	24,3	0,3	0,45	disease	0,67	disease	0,9	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,66	high_impact	2,75	0,42	0,8	68,72	19,93	P	0,78	P	0,91	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8182	8182	C	A	MI.6458	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	597	199	I	M	atC/atA	7,44	1	0	probably_damaging	1	neutral	0,27	neutral	1,83	neutral	-1,37	deleterious	-2,88	medium_impact	3,02	damaging	0,15	damaging	0,03	deleterious	3,92	23,5	0,41	0,5	disease	0,64	disease	0,74	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,79	low_impact	-3,52	medium_impact	-0,03	medium_impact	1,73	0,79	0,85	68,72	19,93	P	0,88	P	0,79	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8182	8182	C	G	MI.6459	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	597	199	I	M	atC/atG	7,44	1	0	probably_damaging	1	neutral	0,27	neutral	1,83	neutral	-1,37	deleterious	-2,88	medium_impact	3,02	damaging	0,15	damaging	0,03	deleterious	3,56	23,1	0,41	0,5	disease	0,64	disease	0,74	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,79	low_impact	-3,52	medium_impact	-0,03	medium_impact	1,73	0,79	0,85	68,72	19,93	P	0,88	P	0,79	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8830	8830	C	A	MI.646	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	304	102	L	M	Cta/Ata	-3,57	0	0	probably_damaging	1	neutral	0,69	neutral	4,1	neutral	-1,86	neutral	-0,7	neutral_impact	0,32	neutral	0,84	neutral	0,71	deleterious	1,87	15,38	0,34	0,65	disease	0,58	neutral	0,05	neutral	0,32	neutral	0,31	4	deleterious	1	neutral	0,35	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,49	medium_impact	-0,82	0,7	0,9	18,14	17,58	N	0,3	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8183	8183	T	A	MI.6460	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	598	200	C	S	Tgt/Agt	-2,48	0	0	probably_damaging	1	neutral	0,86	neutral	0,13	deleterious	-6,59	deleterious	-9,59	high_impact	4,21	damaging	0,11	damaging	0,02	deleterious	3,69	23,3	0,23	0,45	disease	0,62	disease	0,92	disease	0,82	disease	0,73	5	deleterious	0,99	neutral	0,43	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,64	high_impact	2,84	0,42	0,8	68,72	19,58	P	0,59	P	0,84	disease_causing	0,99	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8183	8183	T	C	MI.6461	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	598	200	C	R	Tgt/Cgt	-2,48	0	0	probably_damaging	1	neutral	0,53	neutral	0,1	deleterious	-8,14	deleterious	-11,51	high_impact	3,86	damaging	0,13	damaging	0,02	deleterious	3,61	23,2	0,19	0,45	disease	0,95	disease	0,94	disease	0,89	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,95	low_impact	-3,52	medium_impact	0,23	high_impact	2,51	0,24	0,8	68,72	19,58	P	0,6	P	0,98	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8183	8183	T	G	MI.6462	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	598	200	C	G	Tgt/Ggt	-2,48	0	0	probably_damaging	1	neutral	0,67	neutral	0,12	deleterious	-6,91	deleterious	-11,51	high_impact	4,21	damaging	0,11	damaging	0,03	deleterious	3,48	23,1	0,18	0,45	disease	0,85	disease	0,92	disease	0,85	disease	0,66	3	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	0,38	high_impact	2,84	0,31	0,8	68,72	19,58	P	0,59	P	0,96	disease_causing	0,99	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8184	8184	G	C	MI.6463	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	599	200	C	S	tGt/tCt	7,44	1	0	probably_damaging	1	neutral	0,86	neutral	0,13	deleterious	-6,59	deleterious	-9,59	high_impact	4,21	damaging	0,11	damaging	0,02	deleterious	3,45	23	0,23	0,45	disease	0,62	disease	0,92	disease	0,82	disease	0,73	5	deleterious	0,99	neutral	0,43	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,64	high_impact	2,84	0,42	0,8	68,72	19,58	P	0,7	P	0,84	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8184	8184	G	A	MI.6464	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	599	200	C	Y	tGt/tAt	7,44	1	0	probably_damaging	1	neutral	0,12	neutral	0,1	deleterious	-8,61	deleterious	-10,55	high_impact	4,55	damaging	0,13	damaging	0,01	deleterious	3,76	23,3	0,21	0,45	disease	0,98	disease	0,96	disease	0,88	disease	0,66	3	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,95	low_impact	-3,52	medium_impact	-0,27	high_impact	3,16	0,44	0,8	68,72	19,58	P	0,78	P	0,97	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8184	8184	G	T	MI.6465	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	599	200	C	F	tGt/tTt	7,44	1	0	probably_damaging	1	neutral	0,21	neutral	0,1	deleterious	-8,21	deleterious	-10,55	high_impact	4,55	damaging	0,1	damaging	0,01	deleterious	4,16	23,8	0,18	0,45	disease	0,97	disease	0,97	disease	0,86	disease	0,61	2	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,95	low_impact	-3,52	medium_impact	-0,11	high_impact	3,16	0,35	0,8	68,72	19,58	P	0,78	P	0,99	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8185	8185	T	G	MI.6466	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	600	200	C	W	tgT/tgG	7,21	1	0	probably_damaging	1	deleterious	0,03	neutral	0,09	deleterious	-10,04	deleterious	-10,55	high_impact	3,86	damaging	0,15	damaging	0,02	deleterious	4,47	24,2	0,16	0,45	disease	0,99	disease	0,94	disease	0,89	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,94	low_impact	-3,52	medium_impact	-0,63	high_impact	2,51	0,25	0,8	68,72	19,58	P	0,79	P	0,99	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8185	8185	T	A	MI.6467	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	600	200	C	W	tgT/tgA	7,21	1	0	probably_damaging	1	deleterious	0,03	neutral	0,09	deleterious	-10,04	deleterious	-10,55	high_impact	3,86	damaging	0,15	damaging	0,02	deleterious	4,57	24,4	0,16	0,45	disease	0,99	disease	0,94	disease	0,89	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,94	low_impact	-3,52	medium_impact	-0,63	high_impact	2,51	0,25	0,8	68,72	19,58	P	0,79	P	0,99	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8186	8186	G	T	MI.6468	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	601	201	G	W	Gga/Tga	-3,17	0	0	probably_damaging	1	neutral	0,18	neutral	-0,27	deleterious	-11,66	deleterious	-7,67	high_impact	4,58	damaging	0,19	damaging	0,02	deleterious	4,7	24,6	0,13	0,4	disease	0,99	disease	0,91	disease	0,84	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,93	low_impact	-3,52	medium_impact	-0,16	high_impact	3,19	0,26	0,8	68,28	19,82	P	0,62	P	0,98	disease_causing	0,89	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8186	8186	G	C	MI.6469	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	601	201	G	R	Gga/Cga	-3,17	0	0	probably_damaging	1	neutral	0,4	neutral	-0,26	deleterious	-9,1	deleterious	-7,68	high_impact	4,58	damaging	0,18	damaging	0,01	deleterious	4,17	23,8	0,12	0,4	disease	0,98	disease	0,9	disease	0,87	disease	0,74	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,94	low_impact	-3,52	medium_impact	0,11	high_impact	3,19	0,58	0,8	68,28	19,82	P	0,67	P	1	disease_causing	0,84	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8831	8831	T	G	MI.647	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	305	102	L	R	cTa/cGa	-1,03	0	0	probably_damaging	1	deleterious	0,01	neutral	4	deleterious	-4,37	deleterious	-4,6	high_impact	3,81	neutral	0,73	damaging	0,09	deleterious	4,14	23,8	0,13	0,65	disease	0,9	disease	0,88	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,9	low_impact	-3,6	medium_impact	-0,84	high_impact	2,17	0,68	0,9	18,14	17,58	N	0,29	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8187	8187	G	C	MI.6470	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	602	201	G	A	gGa/gCa	2,83	1	0	probably_damaging	1	neutral	0,65	neutral	-0,24	deleterious	-7,57	deleterious	-5,76	high_impact	4,24	damaging	0,22	damaging	0,09	deleterious	3,28	22,8	0,13	0,4	disease	0,96	disease	0,78	disease	0,8	disease	0,72	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,35	high_impact	2,87	0,41	0,8	68,28	19,82	P	0,78	P	0,85	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8187	8187	G	T	MI.6471	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	602	201	G	V	gGa/gTa	2,83	1	0	probably_damaging	1	neutral	0,55	neutral	-0,27	deleterious	-10,17	deleterious	-8,64	high_impact	4,58	damaging	0,14	damaging	0,01	deleterious	3,94	23,5	0,12	0,4	disease	0,99	disease	0,92	disease	0,83	disease	0,72	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	0,25	high_impact	3,19	0,39	0,8	68,28	19,82	P	0,71	P	1	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8187	8187	G	A	MI.6472	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	602	201	G	E	gGa/gAa	2,83	1	0	probably_damaging	1	neutral	0,36	neutral	-0,26	deleterious	-8,84	deleterious	-7,67	high_impact	4,24	damaging	0,18	damaging	0,01	deleterious	4,03	23,6	0,13	0,4	disease	0,98	disease	0,9	disease	0,87	disease	0,74	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	0,07	high_impact	2,87	0,43	0,8	68,28	19,82	P	0,8	P	1	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8189	8189	G	C	MI.6473	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	604	202	A	P	Gca/Cca	-16,08	0	0	possibly_damaging	0,82	neutral	0,39	neutral	1,8	neutral	-2,57	deleterious	-3,88	medium_impact	2,28	damaging	0,29	neutral	0,39	deleterious	3,91	23,5	0,2	0,45	neutral	0,29	disease	0,9	disease	0,64	disease	0,71	4	neutral	0,82	neutral	0,29	NA	0	deleterious	0,75	low_impact	-1,33	medium_impact	0,1	medium_impact	1,03	0,68	0,85	27,75	65,41	P	0,72	P	0,72	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8189	8189	G	A	MI.6474	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	604	202	A	T	Gca/Aca	-16,08	0	0	benign	0,04	neutral	0,52	neutral	1,88	neutral	-1,11	deleterious	-2,54	low_impact	1,35	damaging	0,37	neutral	0,54	deleterious	2,43	19,04	0,58	0,65	neutral	0,22	disease	0,75	neutral	0,38	neutral	0,21	6	neutral	0,44	deleterious	0,74	neutral	-6	neutral	0,23	medium_impact	0,57	medium_impact	0,22	medium_impact	0,16	0,79	0,85	27,75	65,41	P	0,57	P	0,34	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8189	8189	G	T	MI.6475	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	604	202	A	S	Gca/Tca	-16,08	0	0	possibly_damaging	0,45	neutral	0,69	neutral	1,84	neutral	-1,72	neutral	-1,2	low_impact	1	neutral	0,66	neutral	0,91	neutral	1,01	10,71	0,41	0,5	neutral	0,35	disease	0,72	neutral	0,39	neutral	0,21	6	neutral	0,36	deleterious	0,62	neutral	-3	deleterious	0,44	medium_impact	-0,64	medium_impact	0,4	medium_impact	-0,17	0,7	0,85	27,75	65,41	N	0,28	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8190	8190	C	A	MI.6476	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	605	202	A	E	gCa/gAa	1,91	0,98	0	possibly_damaging	0,76	neutral	0,63	neutral	1,81	neutral	-2,32	deleterious	-3,62	medium_impact	2,48	damaging	0,29	neutral	0,46	deleterious	4,45	24,2	0,29	0,45	neutral	0,22	disease	0,9	disease	0,69	disease	0,72	4	neutral	0,72	neutral	0,44	NA	0	deleterious	0,61	low_impact	-1,19	medium_impact	0,33	medium_impact	1,22	0,56	0,8	27,75	65,41	P	0,86	P	0,63	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8190	8190	C	G	MI.6477	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	605	202	A	G	gCa/gGa	1,91	0,98	0	possibly_damaging	0,45	neutral	0,5	neutral	1,79	neutral	-2,9	deleterious	-3	medium_impact	2,38	damaging	0,37	neutral	0,56	deleterious	2,15	17,17	0,37	0,5	disease	0,6	disease	0,8	disease	0,6	disease	0,65	3	neutral	0,47	deleterious	0,53	NA	0	deleterious	0,49	medium_impact	-0,64	medium_impact	0,21	medium_impact	1,13	0,68	0,85	27,75	65,41	P	0,7	P	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8190	8190	C	T	MI.6478	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	605	202	A	V	gCa/gTa	1,91	0,98	0	possibly_damaging	0,45	neutral	0,62	neutral	1,95	neutral	-0,33	deleterious	-3,36	neutral_impact	0,69	damaging	0,3	neutral	0,56	deleterious	4,18	23,8	0,46	0,55	neutral	0,41	disease	0,84	disease	0,56	neutral	0,36	3	neutral	0,39	deleterious	0,59	neutral	-3	deleterious	0,49	medium_impact	-0,64	medium_impact	0,32	medium_impact	-0,46	0,76	0,85	27,75	65,41	P	0,75	P	0,78	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8192	8192	A	G	MI.6479	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	607	203	N	D	Aac/Gac	-8,93	0	0	probably_damaging	0,99	neutral	0,21	neutral	1,92	neutral	0,63	deleterious	-4,8	medium_impact	2,02	damaging	0,31	damaging	0,26	deleterious	4,02	23,6	0,75	0,8	neutral	0,43	disease	0,82	disease	0,74	disease	0,7	4	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,79	low_impact	-2,58	medium_impact	-0,11	medium_impact	0,79	0,52	0,8	67,84	19,5	P	0,58	P	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8831	8831	T	A	MI.648	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	305	102	L	Q	cTa/cAa	-1,03	0	0	probably_damaging	1	deleterious	0,01	neutral	4	deleterious	-4,52	deleterious	-4,37	high_impact	3,81	neutral	0,78	damaging	0,12	deleterious	4,05	23,7	0,15	0,65	disease	0,91	disease	0,76	disease	0,64	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,6	medium_impact	-0,84	high_impact	2,17	0,78	0,9	18,14	17,58	N	0,29	N	0,95	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8192	8192	A	T	MI.6480	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	607	203	N	Y	Aac/Tac	-8,93	0	0	probably_damaging	1	neutral	1	neutral	1,91	neutral	-0,33	deleterious	-7,67	medium_impact	2,34	damaging	0,29	damaging	0,15	deleterious	3,88	23,5	0,44	0,55	neutral	0,36	disease	0,92	disease	0,71	disease	0,73	5	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,83	low_impact	-3,52	high_impact	1,86	medium_impact	1,09	0,36	0,8	67,84	19,5	P	0,55	P	0,98	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8192	8192	A	C	MI.6481	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	607	203	N	H	Aac/Cac	-8,93	0	0	probably_damaging	1	neutral	0,68	neutral	1,85	neutral	-1,89	deleterious	-4,8	high_impact	3,52	damaging	0,26	damaging	0,18	deleterious	3,22	22,7	0,57	0,65	neutral	0,28	disease	0,85	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,79	low_impact	-3,52	medium_impact	0,39	high_impact	2,2	0,36	0,8	67,84	19,5	P	0,68	P	0,94	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8193	8193	A	G	MI.6482	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	608	203	N	S	aAc/aGc	6,75	1	0	probably_damaging	0,97	neutral	0,57	neutral	1,92	neutral	0,5	deleterious	-4,8	medium_impact	2,27	damaging	0,25	neutral	0,31	deleterious	3,12	22,6	0,74	0,75	neutral	0,22	disease	0,86	disease	0,71	disease	0,71	4	neutral	0,97	neutral	0,3	deleterious	1	deleterious	0,78	low_impact	-2,13	medium_impact	0,27	medium_impact	1,02	0,28	0,8	67,84	19,5	P	0,9	P	0,87	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8193	8193	A	C	MI.6483	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	608	203	N	T	aAc/aCc	6,75	1	0	probably_damaging	0,99	neutral	0,39	neutral	1,88	neutral	-0,89	deleterious	-5,76	high_impact	4,07	damaging	0,25	damaging	0,26	deleterious	3,46	23	0,53	0,6	neutral	0,49	disease	0,89	disease	0,73	disease	0,73	5	deleterious	0,99	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-2,58	medium_impact	0,1	high_impact	2,71	0,46	0,8	67,84	19,5	P	0,93	P	0,92	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8193	8193	A	T	MI.6484	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	608	203	N	I	aAc/aTc	6,75	1	0	probably_damaging	1	neutral	0,48	neutral	1,86	neutral	-2,37	deleterious	-8,63	high_impact	4,07	damaging	0,27	neutral	0,36	deleterious	3,97	23,6	0,34	0,5	disease	0,69	disease	0,93	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,19	high_impact	2,71	0,22	0,8	67,84	19,5	P	0,9	P	0,97	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8194	8194	C	G	MI.6485	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	609	203	N	K	aaC/aaG	6,75	1	0	probably_damaging	1	neutral	0,33	neutral	1,89	neutral	-0,03	deleterious	-5,76	medium_impact	3,17	damaging	0,27	damaging	0,17	deleterious	4,2	23,9	0,7	0,75	neutral	0,38	disease	0,9	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,84	low_impact	-3,52	medium_impact	0,04	medium_impact	1,87	0,53	0,8	67,84	19,5	P	0,89	P	0,99	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8194	8194	C	A	MI.6486	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	609	203	N	K	aaC/aaA	6,75	1	0	probably_damaging	1	neutral	0,33	neutral	1,89	neutral	-0,03	deleterious	-5,76	medium_impact	3,17	damaging	0,27	damaging	0,17	deleterious	4,64	24,5	0,7	0,75	neutral	0,38	disease	0,9	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,84	low_impact	-3,52	medium_impact	0,04	medium_impact	1,87	0,53	0,8	67,84	19,5	P	0,89	P	0,99	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8195	8195	C	G	MI.6487	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	610	204	H	D	Cac/Gac	-2,94	0	0	probably_damaging	1	neutral	0,2	neutral	0,23	deleterious	-9,28	deleterious	-8,63	high_impact	4,57	damaging	0,2	damaging	0,02	deleterious	4,02	23,6	0,16	0,45	disease	0,98	disease	0,86	disease	0,92	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	-0,13	high_impact	3,18	0,32	0,8	68,28	19,44	P	0,65	P	0,97	disease_causing	0,98	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8195	8195	C	T	MI.6488	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	610	204	H	Y	Cac/Tac	-2,94	0	0	probably_damaging	0,99	neutral	1	neutral	0,3	deleterious	-5,46	deleterious	-5,75	high_impact	4,22	damaging	0,18	damaging	0,01	deleterious	3,86	23,5	0,23	0,45	disease	0,76	disease	0,88	disease	0,89	disease	0,75	5	deleterious	0,99	deleterious	0,51	deleterious	2	deleterious	0,89	low_impact	-2,58	high_impact	1,86	high_impact	2,85	0,34	0,8	68,28	19,44	P	0,61	P	0,99	disease_causing	0,95	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8195	8195	C	A	MI.6489	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	610	204	H	N	Cac/Aac	-2,94	0	0	probably_damaging	1	neutral	0,34	neutral	0,24	deleterious	-7,84	deleterious	-6,71	high_impact	4,57	damaging	0,17	damaging	0,01	deleterious	4,17	23,8	0,22	0,45	disease	0,96	disease	0,83	disease	0,89	disease	0,73	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0,05	high_impact	3,18	0,31	0,8	68,28	19,44	P	0,71	P	0,96	disease_causing	0,94	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8831	8831	T	C	MI.649	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	305	102	L	P	cTa/cCa	-1,03	0	0	probably_damaging	1	deleterious	0	neutral	3,99	deleterious	-4,94	deleterious	-5,16	high_impact	3,81	neutral	0,8	damaging	0,12	deleterious	3,79	23,4	0,13	0,65	disease	0,93	disease	0,86	disease	0,75	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,17	0,68	0,9	18,14	17,58	N	0,29	N	0,97	disease_causing	0,99	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8196	8196	A	G	MI.6490	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	611	204	H	R	cAc/cGc	7,21	1	0	probably_damaging	1	neutral	0,35	neutral	0,23	deleterious	-8,72	deleterious	-7,67	high_impact	4,22	damaging	0,19	damaging	0,01	deleterious	3,16	22,6	0,24	0,45	disease	0,97	disease	0,86	disease	0,91	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,93	low_impact	-3,52	medium_impact	0,06	high_impact	2,85	0,33	0,8	68,28	19,44	P	0,78	P	0,95	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8196	8196	A	C	MI.6491	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	611	204	H	P	cAc/cCc	7,21	1	0	probably_damaging	1	neutral	0,2	neutral	0,23	deleterious	-9,68	deleterious	-9,59	high_impact	4,57	damaging	0,15	damaging	0,04	deleterious	3,37	22,9	0,17	0,45	disease	0,98	disease	0,89	disease	0,88	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	-0,13	high_impact	3,18	0,26	0,8	68,28	19,44	P	0,78	P	0,98	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8196	8196	A	T	MI.6492	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	611	204	H	L	cAc/cTc	7,21	1	0	probably_damaging	1	neutral	0,66	neutral	0,23	deleterious	-8,06	deleterious	-10,55	high_impact	4,57	damaging	0,13	damaging	0,01	deleterious	4,05	23,7	0,15	0,45	disease	0,91	disease	0,89	disease	0,89	disease	0,69	4	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,9	low_impact	-3,52	medium_impact	0,36	high_impact	3,18	0,32	0,8	68,28	19,44	P	0,76	P	0,91	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8197	8197	C	G	MI.6493	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	612	204	H	Q	caC/caG	6,75	1	0	probably_damaging	1	neutral	0,3	neutral	0,23	deleterious	-8,52	deleterious	-7,67	high_impact	4,22	damaging	0,14	damaging	0,02	deleterious	3,72	23,3	0,24	0,45	disease	0,97	disease	0,84	disease	0,9	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0	high_impact	2,85	0,42	0,8	68,28	19,44	P	0,8	P	0,94	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8197	8197	C	A	MI.6494	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	612	204	H	Q	caC/caA	6,75	1	0	probably_damaging	1	neutral	0,3	neutral	0,23	deleterious	-8,52	deleterious	-7,67	high_impact	4,22	damaging	0,14	damaging	0,02	deleterious	4,08	23,7	0,24	0,45	disease	0,97	disease	0,84	disease	0,9	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,89	low_impact	-3,52	medium_impact	0	high_impact	2,85	0,42	0,8	68,28	19,44	P	0,8	P	0,94	disease_causing	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8198	8198	A	G	MI.6495	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	613	205	S	G	Agt/Ggt	-2,94	0	0	probably_damaging	0,99	neutral	0,38	neutral	1,8	neutral	-0,88	deleterious	-3,84	low_impact	1,86	damaging	0,15	damaging	0,04	deleterious	3,51	23,1	0,38	0,5	disease	0,51	disease	0,71	disease	0,75	disease	0,71	4	deleterious	0,99	neutral	0,2	neutral	-2	deleterious	0,76	low_impact	-2,58	medium_impact	0,09	medium_impact	0,64	0,72	0,85	67,84	18,95	P	0,81	P	0,79	polymorphism	0,62	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8198	8198	A	C	MI.6496	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	613	205	S	R	Agt/Cgt	-2,94	0	0	probably_damaging	1	neutral	0,34	neutral	1,83	neutral	-2,16	deleterious	-4,8	high_impact	3,83	damaging	0,17	damaging	0,02	deleterious	3,79	23,4	0,23	0,45	disease	0,65	disease	0,86	disease	0,81	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	0,05	high_impact	2,49	0,64	0,8	67,84	18,95	P	0,79	P	1	disease_causing	0,76	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8198	8198	A	T	MI.6497	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	613	205	S	C	Agt/Tgt	-2,94	0	0	probably_damaging	1	neutral	0,18	neutral	1,76	deleterious	-4,84	deleterious	-4,79	high_impact	3,83	damaging	0,19	damaging	0,03	deleterious	3,45	23	0,25	0,45	disease	0,92	disease	0,8	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	-0,16	high_impact	2,49	0,7	0,85	67,84	18,95	P	0,78	P	0,91	disease_causing	0,72	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8199	8199	G	A	MI.6498	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	614	205	S	N	aGt/aAt	5,83	1	0	probably_damaging	0,97	neutral	0,35	neutral	1,82	neutral	-2,45	deleterious	-2,88	high_impact	3,83	damaging	0,16	damaging	0,03	deleterious	3,67	23,2	0,53	0,6	disease	0,65	disease	0,74	disease	0,75	disease	0,71	4	neutral	0,98	neutral	0,19	deleterious	2	deleterious	0,79	low_impact	-2,13	medium_impact	0,06	high_impact	2,49	0,5	0,8	67,84	18,95	P	0,86	P	0,8	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8199	8199	G	C	MI.6499	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	614	205	S	T	aGt/aCt	5,83	1	0	probably_damaging	0,97	neutral	0,39	neutral	1,83	neutral	-1,97	deleterious	-2,88	medium_impact	3,48	damaging	0,16	damaging	0,03	deleterious	3,64	23,2	0,32	0,5	neutral	0,4	disease	0,75	disease	0,75	disease	0,7	4	neutral	0,97	neutral	0,21	deleterious	1	deleterious	0,78	low_impact	-2,13	medium_impact	0,1	high_impact	2,16	0,79	0,85	67,84	18,95	P	0,85	P	0,53	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8555	8555	T	G	MI.65	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	29	10	I	S	aTt/aGt	-3,11	0	0	benign	0	neutral	0,23	neutral	4,74	neutral	0,07	neutral	-0,29	neutral_impact	0,68	neutral	0,85	neutral	0,83	deleterious	2,52	19,6	0,33	0,65	neutral	0,41	neutral	0,43	neutral	0,22	neutral	0,47	1	neutral	0,77	deleterious	0,62	neutral	-6	neutral	0,13	high_impact	2,09	medium_impact	-0,01	medium_impact	-0,52	0,38	0,9	27,43	16,7	N	0,45	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8833	8833	G	C	MI.650	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	307	103	A	P	Gcc/Ccc	-0,33	0,56	0	probably_damaging	1	neutral	0,14	neutral	4,15	deleterious	-3,81	deleterious	-2,64	medium_impact	1,97	neutral	0,74	neutral	0,39	deleterious	3,76	23,3	0,1	0,65	disease	0,89	disease	0,87	disease	0,72	disease	0,74	5	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,88	low_impact	-3,6	medium_impact	-0,15	medium_impact	0,59	0,79	0,9	22,12	23,58	N	0,26	N	0,86	disease_causing	0,73	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8199	8199	G	T	MI.6500	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	614	205	S	I	aGt/aTt	5,83	1	0	probably_damaging	1	neutral	0,41	neutral	1,79	neutral	-2,86	deleterious	-5,75	high_impact	3,62	damaging	0,19	damaging	0,03	deleterious	4,28	24	0,24	0,45	disease	0,82	disease	0,91	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	0,12	high_impact	2,29	0,73	0,85	67,84	18,95	P	0,86	P	0,99	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8201	8201	T	C	MI.6501	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	616	206	F	L	Ttc/Ctc	-0,4	0,15	0	probably_damaging	0,99	neutral	0,54	neutral	1,94	neutral	-0,92	deleterious	-5,73	medium_impact	2,48	damaging	0,24	damaging	0,03	deleterious	4,28	24	0,36	0,5	neutral	0,25	disease	0,78	disease	0,7	disease	0,68	4	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,75	low_impact	-2,58	medium_impact	0,24	medium_impact	1,22	0,55	0,8	68,28	18,65	P	0,73	P	0,81	disease_causing	0,65	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8201	8201	T	G	MI.6502	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	616	206	F	V	Ttc/Gtc	-0,4	0,15	0	probably_damaging	1	neutral	0,44	neutral	1,88	neutral	-1,87	deleterious	-6,68	high_impact	3,75	damaging	0,24	damaging	0,02	deleterious	4,33	24	0,33	0,5	disease	0,52	disease	0,88	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,8	low_impact	-3,52	medium_impact	0,15	high_impact	2,41	0,37	0,8	68,28	18,65	P	0,71	P	0,92	disease_causing	0,78	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8201	8201	T	A	MI.6503	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	616	206	F	I	Ttc/Atc	-0,4	0,15	0	probably_damaging	1	neutral	0,36	neutral	1,87	neutral	-2,62	deleterious	-5,73	high_impact	3,75	damaging	0,26	damaging	0,04	deleterious	4,63	24,5	0,26	0,45	neutral	0,32	disease	0,85	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,78	low_impact	-3,52	medium_impact	0,07	high_impact	2,41	0,51	0,8	68,28	18,65	P	0,73	P	0,87	disease_causing	0,62	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8202	8202	T	C	MI.6504	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	617	206	F	S	tTc/tCc	5,83	1	0	probably_damaging	1	neutral	0,41	neutral	1,85	neutral	-0,58	deleterious	-7,64	medium_impact	3,06	damaging	0,25	damaging	0,02	deleterious	4,43	24,2	0,31	0,45	neutral	0,37	disease	0,86	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	0,12	medium_impact	1,76	0,3	0,8	68,28	18,65	P	0,79	P	0,96	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8202	8202	T	G	MI.6505	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	617	206	F	C	tTc/tGc	5,83	1	0	probably_damaging	1	neutral	0,19	neutral	1,81	deleterious	-4,58	deleterious	-7,64	high_impact	4,3	damaging	0,25	damaging	0,02	deleterious	4,26	23,9	0,19	0,45	disease	0,83	disease	0,84	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,82	low_impact	-3,52	medium_impact	-0,14	high_impact	2,93	0,23	0,8	68,28	18,65	P	0,78	P	1	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8202	8202	T	A	MI.6506	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	617	206	F	Y	tTc/tAc	5,83	1	0	probably_damaging	0,99	neutral	0,84	neutral	1,87	neutral	-1,27	deleterious	-2,8	low_impact	1,92	damaging	0,5	neutral	0,56	deleterious	4,32	24	0,32	0,5	disease	0,62	disease	0,78	disease	0,67	disease	0,57	1	deleterious	0,99	neutral	0,43	neutral	-2	deleterious	0,8	low_impact	-2,58	medium_impact	0,6	medium_impact	0,7	0,51	0,8	68,28	18,65	P	0,59	P	0,76	disease_causing	0,97	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8203	8203	C	G	MI.6507	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	618	206	F	L	ttC/ttG	3,06	0,99	0	probably_damaging	0,99	neutral	0,54	neutral	1,94	neutral	-0,92	deleterious	-5,73	medium_impact	2,48	damaging	0,24	damaging	0,03	deleterious	4,53	24,3	0,36	0,5	neutral	0,25	disease	0,78	disease	0,7	disease	0,68	4	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,75	low_impact	-2,58	medium_impact	0,24	medium_impact	1,22	0,55	0,8	68,28	18,65	P	0,8	P	0,81	disease_causing	0,97	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8203	8203	C	A	MI.6508	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	618	206	F	L	ttC/ttA	3,06	0,99	0	probably_damaging	0,99	neutral	0,54	neutral	1,94	neutral	-0,92	deleterious	-5,73	medium_impact	2,48	damaging	0,24	damaging	0,03	deleterious	4,87	24,9	0,36	0,5	neutral	0,25	disease	0,78	disease	0,7	disease	0,68	4	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,75	low_impact	-2,58	medium_impact	0,24	medium_impact	1,22	0,55	0,8	68,28	18,65	P	0,8	P	0,81	disease_causing	0,97	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8204	8204	A	G	MI.6509	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	619	207	M	V	Atg/Gtg	-4,09	0	0	probably_damaging	0,97	neutral	0,52	neutral	1,02	deleterious	-5,6	deleterious	-3,84	high_impact	4,56	damaging	0,12	damaging	0,03	deleterious	2,98	22,2	0,31	0,45	disease	0,74	disease	0,86	disease	0,81	disease	0,71	4	neutral	0,96	neutral	0,28	deleterious	2	deleterious	0,86	low_impact	-2,13	medium_impact	0,22	high_impact	3,17	0,37	0,8	68,72	19,3	P	0,67	P	0,89	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8833	8833	G	A	MI.651	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	307	103	A	T	Gcc/Acc	-0,33	0,56	0	probably_damaging	1	neutral	0,54	neutral	4,29	neutral	-0,74	neutral	-2,15	low_impact	1,18	neutral	0,89	neutral	0,63	deleterious	4,18	23,8	0,42	0,65	disease	0,52	neutral	0,45	neutral	0,39	neutral	0,39	2	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,33	medium_impact	-0,09	0,73	0,9	22,12	23,58	N	0,28	N	0,52	polymorphism	0,57	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8204	8204	A	T	MI.6510	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	619	207	M	L	Atg/Ttg	-4,09	0	0	probably_damaging	0,95	neutral	0,65	neutral	1,12	deleterious	-4,78	deleterious	-2,88	high_impact	4,21	damaging	0,13	damaging	0,03	deleterious	3,58	23,2	0,24	0,45	disease	0,63	disease	0,82	disease	0,79	disease	0,72	4	neutral	0,94	neutral	0,35	deleterious	2	deleterious	0,82	low_impact	-1,91	medium_impact	0,35	high_impact	2,84	0,34	0,8	68,72	19,3	P	0,7	P	0,7	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8204	8204	A	C	MI.6511	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	619	207	M	L	Atg/Ctg	-4,09	0	0	probably_damaging	0,95	neutral	0,65	neutral	1,12	deleterious	-4,78	deleterious	-2,88	high_impact	4,21	damaging	0,13	damaging	0,03	deleterious	3,6	23,2	0,24	0,45	disease	0,63	disease	0,82	disease	0,79	disease	0,72	4	neutral	0,94	neutral	0,35	deleterious	2	deleterious	0,82	low_impact	-1,91	medium_impact	0,35	high_impact	2,84	0,34	0,8	68,72	19,3	P	0,69	P	0,7	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8205	8205	T	C	MI.6512	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	620	207	M	T	aTg/aCg	8,59	1	0	probably_damaging	1	neutral	0,38	neutral	0,96	deleterious	-6,15	deleterious	-5,75	high_impact	3,87	damaging	0,14	damaging	0,04	deleterious	3,18	22,7	0,26	0,45	disease	0,76	disease	0,89	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,91	low_impact	-3,52	medium_impact	0,09	high_impact	2,52	0,2	0,8	68,72	19,3	P	0,74	P	0,92	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8205	8205	T	A	MI.6513	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	620	207	M	K	aTg/aAg	8,59	1	0	probably_damaging	1	neutral	0,3	neutral	0,96	deleterious	-6,15	deleterious	-5,75	high_impact	4,56	damaging	0,15	damaging	0,02	deleterious	4,29	24	0,14	0,4	disease	0,89	disease	0,92	disease	0,85	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,92	low_impact	-3,52	medium_impact	0	high_impact	3,17	0,28	0,8	68,72	19,3	P	0,86	P	1	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8206	8206	G	C	MI.6514	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	621	207	M	I	atG/atC	4,67	1	0,05	probably_damaging	0,98	neutral	0,43	neutral	1,02	deleterious	-5,57	deleterious	-3,84	high_impact	3,87	damaging	0,18	damaging	0,04	deleterious	3,76	23,3	0,29	0,45	disease	0,75	disease	0,86	disease	0,81	disease	0,7	4	neutral	0,98	neutral	0,23	deleterious	2	deleterious	0,88	low_impact	-2,3	medium_impact	0,14	high_impact	2,52	0,42	0,8	68,72	19,3	P	0,83	P	0,78	disease_causing	1	0,26	rs28358883	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8206	8206	G	T	MI.6515	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	621	207	M	I	atG/atT	4,67	1	0,05	probably_damaging	0,98	neutral	0,43	neutral	1,02	deleterious	-5,57	deleterious	-3,84	high_impact	3,87	damaging	0,18	damaging	0,04	deleterious	3,87	23,5	0,29	0,45	disease	0,75	disease	0,86	disease	0,81	disease	0,7	4	neutral	0,98	neutral	0,23	deleterious	2	deleterious	0,88	low_impact	-2,3	medium_impact	0,14	high_impact	2,52	0,42	0,8	68,72	19,3	P	0,83	P	0,78	disease_causing	1	0,26	rs28358883	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8207	8207	C	G	MI.6516	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	622	208	P	A	Ccc/Gcc	-2,24	0	0	probably_damaging	1	neutral	0,51	neutral	1,86	neutral	-1,69	deleterious	-7,67	medium_impact	2,67	damaging	0,14	damaging	0,09	deleterious	3,27	22,8	0,37	0,5	neutral	0,35	disease	0,72	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,77	low_impact	-3,52	medium_impact	0,21	medium_impact	1,4	0,61	0,8	67,84	19,2	P	0,68	P	0,9	polymorphism	0,6	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8207	8207	C	T	MI.6517	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	622	208	P	S	Ccc/Tcc	-2,24	0	0	probably_damaging	1	neutral	0,43	neutral	1,84	neutral	-1,76	deleterious	-7,67	high_impact	3,56	damaging	0,09	damaging	0,02	deleterious	4,07	23,7	0,46	0,55	neutral	0,46	disease	0,85	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,83	low_impact	-3,52	medium_impact	0,14	high_impact	2,23	0,22	0,8	67,84	19,2	P	0,7	P	0,94	disease_causing	0,52	0,07	.	.	.	.	.	.	COSM5655026	.	.	.	.	.	.	.	.
chrM	8207	8207	C	A	MI.6518	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	622	208	P	T	Ccc/Acc	-2,24	0	0	probably_damaging	1	neutral	0,4	neutral	1,85	neutral	-1,99	deleterious	-7,67	high_impact	4,12	damaging	0,11	damaging	0,02	deleterious	3,86	23,5	0,35	0,5	disease	0,53	disease	0,85	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	0,11	high_impact	2,76	0,58	0,8	67,84	19,2	P	0,66	P	0,96	disease_causing	0,51	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8208	8208	C	A	MI.6519	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	623	208	P	H	cCc/cAc	4,44	0,99	0	probably_damaging	1	neutral	0,55	neutral	1,82	deleterious	-3,2	deleterious	-8,63	high_impact	4,46	damaging	0,1	damaging	0,02	deleterious	4,14	23,8	0,31	0,45	disease	0,69	disease	0,88	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	0,25	high_impact	3,08	0,43	0,8	67,84	19,2	P	0,74	P	0,79	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8833	8833	G	T	MI.652	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	307	103	A	S	Gcc/Tcc	-0,33	0,56	0	probably_damaging	0,99	neutral	1	neutral	4,38	neutral	-0,06	neutral	-0,6	neutral_impact	0,16	neutral	0,9	neutral	0,8	deleterious	2,54	19,75	0,44	0,65	disease	0,51	neutral	0,38	neutral	0,34	neutral	0,35	3	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,72	low_impact	-2,65	high_impact	1,98	medium_impact	-0,96	0,85	0,9	22,12	23,58	N	0,25	N	0,04	polymorphism	0,75	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8208	8208	C	G	MI.6520	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	623	208	P	R	cCc/cGc	4,44	0,99	0	probably_damaging	1	neutral	0,34	neutral	1,89	neutral	-1,01	deleterious	-8,63	medium_impact	3,11	damaging	0,12	damaging	0,02	deleterious	3,74	23,3	0,29	0,45	neutral	0,44	disease	0,91	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,85	low_impact	-3,52	medium_impact	0,05	medium_impact	1,81	0,51	0,8	67,84	19,2	P	0,79	P	0,85	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8208	8208	C	T	MI.6521	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	623	208	P	L	cCc/cTc	4,44	0,99	0	probably_damaging	1	neutral	0,65	neutral	1,93	neutral	-1,82	deleterious	-9,59	high_impact	3,65	damaging	0,08	damaging	0,03	deleterious	4,58	24,4	0,39	0,5	neutral	0,35	disease	0,89	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,81	low_impact	-3,52	medium_impact	0,35	high_impact	2,32	0,71	0,85	67,84	19,2	P	0,75	P	0,92	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8210	8210	A	C	MI.6522	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	625	209	I	L	Atc/Ctc	-11,47	0	0	probably_damaging	0,97	neutral	0,52	neutral	1,77	neutral	-1,51	neutral	-1,92	medium_impact	2,82	damaging	0,32	neutral	0,35	deleterious	4,01	23,6	0,45	0,55	disease	0,57	disease	0,7	neutral	0,49	disease	0,51	0	neutral	0,96	neutral	0,28	deleterious	1	deleterious	0,71	low_impact	-2,13	medium_impact	0,22	medium_impact	1,54	0,74	0,85	68,28	18,44	P	0,6	P	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8210	8210	A	T	MI.6523	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	625	209	I	F	Atc/Ttc	-11,47	0	0	probably_damaging	1	neutral	0,63	neutral	1,68	neutral	-0,53	deleterious	-3,83	medium_impact	2,35	damaging	0,32	damaging	0,25	deleterious	4,07	23,7	0,47	0,55	neutral	0,24	disease	0,83	disease	0,51	disease	0,67	3	deleterious	0,99	neutral	0,32	deleterious	1	deleterious	0,77	low_impact	-3,52	medium_impact	0,33	medium_impact	1,1	0,77	0,85	68,28	18,44	N	0,51	P	0,92	polymorphism	0,95	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8210	8210	A	G	MI.6524	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	625	209	I	V	Atc/Gtc	-11,47	0	0	probably_damaging	0,92	neutral	0,63	neutral	1,81	neutral	-1,44	neutral	-0,93	medium_impact	2,7	damaging	0,46	neutral	0,4	deleterious	3,2	22,7	0,62	0,65	neutral	0,5	disease	0,54	neutral	0,39	neutral	0,48	0	neutral	0,9	neutral	0,36	deleterious	1	deleterious	0,67	low_impact	-1,71	medium_impact	0,33	medium_impact	1,43	0,39	0,8	68,28	18,44	N	0,36	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8211	8211	T	G	MI.6525	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	626	209	I	S	aTc/aGc	6,98	1	0	probably_damaging	1	neutral	0,44	neutral	1,71	neutral	-2,94	deleterious	-5,74	high_impact	4,41	damaging	0,32	neutral	0,34	deleterious	4,49	24,3	0,32	0,5	disease	0,53	disease	0,87	disease	0,56	disease	0,68	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	0,15	high_impact	3,03	0,45	0,8	68,28	18,44	P	0,77	P	0,91	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8211	8211	T	C	MI.6526	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	626	209	I	T	aTc/aCc	6,98	1	0	probably_damaging	1	neutral	0,37	neutral	1,71	neutral	-2,55	deleterious	-4,76	medium_impact	3,37	damaging	0,3	neutral	0,28	deleterious	3,62	23,2	0,47	0,55	disease	0,6	disease	0,81	neutral	0,45	disease	0,66	3	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,85	low_impact	-3,52	medium_impact	0,08	high_impact	2,05	0,56	0,8	68,28	18,44	P	0,72	P	0,96	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8211	8211	T	A	MI.6527	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	626	209	I	N	aTc/aAc	6,98	1	0	probably_damaging	1	neutral	0,27	neutral	1,67	deleterious	-4,22	deleterious	-6,7	high_impact	4,06	damaging	0,34	damaging	0,24	deleterious	4,64	24,5	0,3	0,45	disease	0,87	disease	0,85	disease	0,56	disease	0,74	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,86	low_impact	-3,52	medium_impact	-0,03	high_impact	2,7	0,47	0,8	68,28	18,44	P	0,7	P	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8212	8212	C	A	MI.6528	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	627	209	I	M	atC/atA	5,6	1	0	probably_damaging	1	neutral	0,32	neutral	1,7	neutral	-2,71	deleterious	-2,86	medium_impact	3,12	damaging	0,36	neutral	0,35	deleterious	4,05	23,7	0,42	0,55	disease	0,76	disease	0,72	disease	0,54	disease	0,64	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	0,02	medium_impact	1,82	0,75	0,85	68,28	18,44	P	0,73	P	0,79	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8212	8212	C	G	MI.6529	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	627	209	I	M	atC/atG	5,6	1	0	probably_damaging	1	neutral	0,32	neutral	1,7	neutral	-2,71	deleterious	-2,86	medium_impact	3,12	damaging	0,36	neutral	0,35	deleterious	3,54	23,1	0,42	0,55	disease	0,76	disease	0,72	disease	0,54	disease	0,64	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,8	low_impact	-3,52	medium_impact	0,02	medium_impact	1,82	0,75	0,85	68,28	18,44	P	0,72	P	0,79	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8834	8834	C	G	MI.653	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	308	103	A	G	gCc/gGc	2,21	0,99	0	probably_damaging	0,99	neutral	0,86	neutral	4,26	neutral	-1,06	neutral	2,17	neutral_impact	-0,62	neutral	0,82	neutral	0,95	neutral	1,19	11,67	0,3	0,65	neutral	0,42	neutral	0,11	neutral	0,29	neutral	0,24	5	deleterious	0,99	neutral	0,44	neutral	-2	deleterious	0,67	low_impact	-2,65	medium_impact	0,74	low_impact	-1,63	0,85	0,9	22,12	23,58	N	0,34	N	0,01	polymorphism	0,62	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8213	8213	G	T	MI.6530	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	628	210	V	F	Gtc/Ttc	-2,24	0	0	probably_damaging	1	neutral	0,56	neutral	1,83	deleterious	-3,91	deleterious	-4,1	medium_impact	2,93	damaging	0,43	neutral	0,35	deleterious	4	23,6	0,17	0,45	disease	0,83	disease	0,91	disease	0,58	disease	0,72	4	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,85	low_impact	-3,52	medium_impact	0,26	medium_impact	1,64	0,78	0,85	67,84	17,77	N	0,41	N	0,94	disease_causing	0,9	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8213	8213	G	C	MI.6531	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	628	210	V	L	Gtc/Ctc	-2,24	0	0	probably_damaging	0,97	neutral	0,46	neutral	1,91	neutral	-2,33	neutral	-2,43	medium_impact	2,73	damaging	0,47	neutral	0,42	deleterious	3,7	23,3	0,36	0,5	neutral	0,41	disease	0,77	disease	0,54	disease	0,61	2	neutral	0,97	neutral	0,25	deleterious	1	deleterious	0,75	low_impact	-2,13	medium_impact	0,17	medium_impact	1,45	0,57	0,8	67,84	17,77	N	0,39	N	0,23	polymorphism	0,54	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8213	8213	G	A	MI.6532	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	628	210	V	I	Gtc/Atc	-2,24	0	0	probably_damaging	0,97	neutral	0,43	neutral	1,85	neutral	-2,36	neutral	-0,91	medium_impact	2,86	damaging	0,46	neutral	0,48	deleterious	3,78	23,4	0,39	0,5	disease	0,76	disease	0,66	neutral	0,43	neutral	0,48	0	neutral	0,97	neutral	0,23	deleterious	1	deleterious	0,75	low_impact	-2,13	medium_impact	0,14	medium_impact	1,58	0,81	0,85	67,84	17,77	N	0,41	N	0,3	polymorphism	0,8	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8214	8214	T	G	MI.6533	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	629	210	V	G	gTc/gGc	4,44	1	0	probably_damaging	1	neutral	0,27	neutral	1,8	neutral	-2,61	deleterious	-5,41	medium_impact	2,79	damaging	0,48	neutral	0,46	deleterious	4,03	23,6	0,23	0,45	disease	0,68	disease	0,82	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,79	low_impact	-3,52	medium_impact	-0,03	medium_impact	1,51	0,5	0,8	67,84	17,77	N	0,47	N	0,84	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8214	8214	T	A	MI.6534	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	629	210	V	D	gTc/gAc	4,44	1	0	probably_damaging	1	neutral	0,18	neutral	1,8	neutral	-1,81	deleterious	-5,46	medium_impact	2,47	damaging	0,42	neutral	0,34	deleterious	4,68	24,6	0,16	0,45	neutral	0,31	disease	0,9	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,77	low_impact	-3,52	medium_impact	-0,16	medium_impact	1,21	0,65	0,8	67,84	17,77	P	0,6	P	0,9	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8214	8214	T	C	MI.6535	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	629	210	V	A	gTc/gCc	4,44	1	0	probably_damaging	1	neutral	0,41	neutral	1,9	neutral	-0,77	deleterious	-2,64	low_impact	1,2	neutral	0,61	neutral	0,62	deleterious	2,58	19,97	0,38	0,5	neutral	0,33	disease	0,58	neutral	0,35	neutral	0,44	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,73	low_impact	-3,52	medium_impact	0,12	medium_impact	0,02	0,53	0,8	67,84	17,77	N	0,47	N	0,59	disease_causing	0,99	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8216	8216	C	G	MI.6536	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	631	211	L	V	Cta/Gta	-7,78	0	0	benign	0,09	neutral	1	neutral	2,02	neutral	2,29	neutral	1,11	neutral_impact	-1,38	neutral	0,79	neutral	0,89	neutral	-1,06	0,01	0,37	0,5	neutral	0,43	neutral	0,15	neutral	0,17	neutral	0,3	4	neutral	0,09	deleterious	0,96	neutral	-6	neutral	0,16	medium_impact	0,22	high_impact	1,86	low_impact	-2,4	0,71	0,85	28,19	51,33	N	0,33	N	0,46	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8216	8216	C	A	MI.6537	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	631	211	L	M	Cta/Ata	-7,78	0	0	possibly_damaging	0,82	neutral	0,33	neutral	1,83	neutral	-2,74	neutral	-0,54	low_impact	0,82	neutral	0,72	neutral	0,54	deleterious	2,56	19,87	0,29	0,45	disease	0,74	neutral	0,27	neutral	0,15	disease	0,58	2	neutral	0,84	neutral	0,26	neutral	-3	deleterious	0,62	low_impact	-1,33	medium_impact	0,04	medium_impact	-0,34	0,82	0,85	28,19	51,33	N	0,47	N	0,55	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8217	8217	T	C	MI.6538	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	632	211	L	P	cTa/cCa	-0,17	0	0	possibly_damaging	0,77	neutral	0,4	neutral	1,7	deleterious	-5,3	deleterious	-3,91	medium_impact	2,66	damaging	0,57	neutral	0,36	deleterious	3,89	23,5	0,15	0,45	disease	0,91	disease	0,84	disease	0,51	disease	0,77	5	neutral	0,77	neutral	0,32	NA	0	deleterious	0,79	low_impact	-1,21	medium_impact	0,11	medium_impact	1,39	0,61	0,8	28,19	51,33	N	0,27	N	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8217	8217	T	G	MI.6539	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	632	211	L	R	cTa/cGa	-0,17	0	0	possibly_damaging	0,6	neutral	0,3	neutral	1,7	deleterious	-5,01	deleterious	-4,22	medium_impact	2,66	neutral	0,63	neutral	0,41	deleterious	4	23,6	0,14	0,4	disease	0,9	disease	0,86	disease	0,64	disease	0,84	7	neutral	0,71	neutral	0,35	NA	0	deleterious	0,69	medium_impact	-0,89	medium_impact	0	medium_impact	1,39	0,46	0,8	28,19	51,33	N	0,27	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8834	8834	C	A	MI.654	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	308	103	A	D	gCc/gAc	2,21	0,99	0	probably_damaging	1	neutral	0,1	neutral	4,16	deleterious	-3,41	neutral	-2,24	medium_impact	3,21	neutral	0,89	neutral	0,51	deleterious	4,53	24,3	0,14	0,65	disease	0,85	disease	0,85	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	-0,25	medium_impact	1,65	0,74	0,9	22,12	23,58	N	0,49	N	0,74	disease_causing	0,77	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8217	8217	T	A	MI.6540	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	632	211	L	Q	cTa/cAa	-0,17	0	0	possibly_damaging	0,6	neutral	0,31	neutral	1,7	deleterious	-5,14	deleterious	-3,66	medium_impact	2,66	neutral	0,68	neutral	0,48	deleterious	4	23,6	0,15	0,4	disease	0,9	disease	0,63	neutral	0,5	disease	0,65	3	neutral	0,71	neutral	0,36	NA	0	deleterious	0,72	medium_impact	-0,89	medium_impact	0,01	medium_impact	1,39	0,7	0,85	28,19	51,33	N	0,32	N	0,92	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8219	8219	G	A	MI.6541	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	634	212	E	K	Gaa/Aaa	-5,01	0	0	possibly_damaging	0,58	neutral	0,87	neutral	1,88	neutral	-0,2	deleterious	-3,82	medium_impact	2,22	damaging	0,24	damaging	0,22	deleterious	4,27	23,9	0,4	0,5	neutral	0,28	disease	0,87	disease	0,68	disease	0,72	4	neutral	0,5	deleterious	0,65	NA	0	deleterious	0,63	medium_impact	-0,85	medium_impact	0,66	medium_impact	0,98	0,67	0,85	68,72	17,48	P	0,79	P	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8219	8219	G	C	MI.6542	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	634	212	E	Q	Gaa/Caa	-5,01	0	0	possibly_damaging	0,63	neutral	0,56	neutral	1,83	neutral	-1,21	deleterious	-2,87	medium_impact	2,27	damaging	0,27	neutral	0,38	deleterious	3,23	22,8	0,42	0,5	disease	0,55	disease	0,71	disease	0,55	disease	0,64	3	neutral	0,58	neutral	0,47	NA	0	deleterious	0,64	medium_impact	-0,94	medium_impact	0,26	medium_impact	1,02	0,7	0,85	68,72	17,48	P	0,87	P	0,76	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8220	8220	A	G	MI.6543	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	635	212	E	G	gAa/gGa	5,13	1	0	possibly_damaging	0,66	neutral	0,39	neutral	1,77	neutral	-2,89	deleterious	-6,7	high_impact	3,81	damaging	0,24	neutral	0,43	deleterious	4,12	23,8	0,37	0,5	disease	0,71	disease	0,73	disease	0,68	disease	0,67	3	neutral	0,69	neutral	0,37	deleterious	1	deleterious	0,69	medium_impact	-0,99	medium_impact	0,1	high_impact	2,47	0,44	0,8	68,72	17,48	P	0,92	P	0,64	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8220	8220	A	C	MI.6544	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	635	212	E	A	gAa/gCa	5,13	1	0	possibly_damaging	0,74	neutral	0,72	neutral	1,83	neutral	-1,67	deleterious	-5,74	medium_impact	3,46	damaging	0,28	neutral	0,35	deleterious	3,58	23,2	0,3	0,45	disease	0,55	disease	0,68	disease	0,64	disease	0,66	3	neutral	0,68	deleterious	0,49	NA	0	deleterious	0,62	low_impact	-1,14	medium_impact	0,43	high_impact	2,14	0,61	0,8	68,72	17,48	P	0,91	P	0,66	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8220	8220	A	T	MI.6545	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	635	212	E	V	gAa/gTa	5,13	1	0	possibly_damaging	0,8	neutral	0,3	neutral	1,79	neutral	-2,87	deleterious	-6,7	medium_impact	2,68	damaging	0,26	neutral	0,29	deleterious	4,21	23,9	0,32	0,5	disease	0,72	disease	0,87	disease	0,66	disease	0,72	4	neutral	0,84	neutral	0,25	NA	0	deleterious	0,79	low_impact	-1,28	medium_impact	0	medium_impact	1,41	0,72	0,85	68,72	17,48	P	0,9	P	0,82	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8221	8221	A	T	MI.6546	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	636	212	E	D	gaA/gaT	8,59	1	0	benign	0,01	neutral	0,59	neutral	1,8	neutral	-1,88	deleterious	-2,87	medium_impact	2,61	damaging	0,35	neutral	0,33	deleterious	2,02	16,35	0,42	0,5	disease	0,61	disease	0,69	disease	0,52	disease	0,58	2	neutral	0,39	deleterious	0,79	neutral	-3	neutral	0,25	medium_impact	1,14	medium_impact	0,29	medium_impact	1,34	0,8	0,85	68,72	17,48	P	0,75	P	0,81	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8221	8221	A	C	MI.6547	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	636	212	E	D	gaA/gaC	8,59	1	0	benign	0,01	neutral	0,59	neutral	1,8	neutral	-1,88	deleterious	-2,87	medium_impact	2,61	damaging	0,35	neutral	0,33	deleterious	1,9	15,62	0,42	0,5	disease	0,61	disease	0,69	disease	0,52	disease	0,58	2	neutral	0,39	deleterious	0,79	neutral	-3	neutral	0,25	medium_impact	1,14	medium_impact	0,29	medium_impact	1,34	0,8	0,85	68,72	17,48	P	0,75	P	0,81	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8222	8222	T	G	MI.6548	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	637	213	L	V	Tta/Gta	0,06	0	0	probably_damaging	0,98	neutral	0,4	neutral	2,31	neutral	1,82	neutral	0,17	neutral_impact	-1,74	neutral	0,66	neutral	0,37	deleterious	2,37	18,63	0,42	0,55	neutral	0,4	neutral	0,41	neutral	0,15	neutral	0,47	1	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,68	low_impact	-2,3	medium_impact	0,11	low_impact	-2,74	0,64	0,8	23,79	40,34	N	0,48	N	0,36	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8222	8222	T	A	MI.6549	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	637	213	L	M	Tta/Ata	0,06	0	0	probably_damaging	1	neutral	0,15	neutral	1,92	neutral	-1,44	neutral	0,28	neutral_impact	-0,92	neutral	0,8	neutral	0,94	deleterious	2,78	21,3	0,36	0,5	neutral	0,47	neutral	0,3	neutral	0,16	neutral	0,45	1	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,7	low_impact	-3,52	medium_impact	-0,21	low_impact	-1,97	0,78	0,85	23,79	40,34	N	0,49	N	0,13	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8834	8834	C	T	MI.655	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	308	103	A	V	gCc/gTc	2,21	0,99	0	probably_damaging	1	neutral	0,37	neutral	4,26	neutral	-1,09	deleterious	-2,99	low_impact	1,64	neutral	0,87	neutral	0,67	deleterious	4,38	24,1	0,33	0,65	neutral	0,38	disease	0,65	disease	0,59	disease	0,63	3	deleterious	1	neutral	0,19	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,16	medium_impact	0,31	0,77	0,9	22,12	23,58	N	0,45	N	0,68	polymorphism	0,57	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8223	8223	T	G	MI.6550	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	638	213	L	W	tTa/tGa	-2,71	0	0	probably_damaging	1	deleterious	0,03	neutral	1,9	deleterious	-3,77	neutral	-1,89	low_impact	0,98	damaging	0,55	damaging	0,16	deleterious	3,94	23,5	0,16	0,45	disease	0,83	disease	0,65	neutral	0,37	disease	0,54	1	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,8	low_impact	-3,52	medium_impact	-0,63	medium_impact	-0,19	0,63	0,8	23,79	40,34	N	0,3	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8223	8223	T	C	MI.6551	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	638	213	L	S	tTa/tCa	-2,71	0	0	probably_damaging	1	neutral	0,82	neutral	2,01	neutral	-0,41	neutral	2,11	neutral_impact	-2,21	neutral	0,72	neutral	0,72	neutral	1,62	13,95	0,31	0,45	neutral	0,23	neutral	0,05	neutral	0,1	neutral	0,24	5	deleterious	1	neutral	0,41	neutral	-2	deleterious	0,65	low_impact	-3,52	medium_impact	0,57	low_impact	-3,18	0,63	0,8	23,79	40,34	N	0,33	N	0,62	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8224	8224	A	T	MI.6552	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	639	213	L	F	ttA/ttT	2,83	0,03	0	probably_damaging	1	neutral	0,15	neutral	1,94	neutral	-1,5	neutral	-0,75	neutral_impact	-1,11	neutral	0,68	neutral	0,55	deleterious	2,63	20,4	0,43	0,55	disease	0,55	neutral	0,46	neutral	0,12	disease	0,61	2	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,74	low_impact	-3,52	medium_impact	-0,21	low_impact	-2,15	0,64	0,8	23,79	40,34	N	0,51	P	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8224	8224	A	C	MI.6553	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	639	213	L	F	ttA/ttC	2,83	0,03	0	probably_damaging	1	neutral	0,15	neutral	1,94	neutral	-1,5	neutral	-0,75	neutral_impact	-1,11	neutral	0,68	neutral	0,55	deleterious	2,52	19,59	0,43	0,55	disease	0,55	neutral	0,46	neutral	0,12	disease	0,61	2	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,74	low_impact	-3,52	medium_impact	-0,21	low_impact	-2,15	0,64	0,8	23,79	40,34	N	0,49	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8225	8225	A	C	MI.6554	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	640	214	I	L	Att/Ctt	-5,7	0	0	probably_damaging	0,97	neutral	0,72	neutral	2,04	neutral	0,4	neutral	-0,95	neutral_impact	0,74	neutral	0,66	neutral	0,68	deleterious	2,76	21,2	0,53	0,6	neutral	0,27	neutral	0,45	neutral	0,25	neutral	0,46	1	neutral	0,96	neutral	0,38	neutral	-2	deleterious	0,64	low_impact	-2,13	medium_impact	0,43	medium_impact	-0,41	0,49	0,8	32,6	72,72	N	0,3	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8225	8225	A	T	MI.6555	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	640	214	I	F	Att/Ttt	-5,7	0	0	probably_damaging	0,99	neutral	0,7	neutral	1,93	neutral	-2,01	deleterious	-2,76	medium_impact	2,79	damaging	0,55	neutral	0,48	deleterious	3,89	23,5	0,54	0,6	neutral	0,24	disease	0,63	disease	0,62	disease	0,71	4	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,71	low_impact	-2,58	medium_impact	0,41	medium_impact	1,51	0,58	0,8	32,6	72,72	N	0,28	N	0,7	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8225	8225	A	G	MI.6556	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	640	214	I	V	Att/Gtt	-5,7	0	0	probably_damaging	0,97	neutral	0,71	neutral	2,16	neutral	2,28	neutral	0,42	neutral_impact	-1,12	neutral	0,75	neutral	0,98	deleterious	0,5	7,4	0,6	0,65	neutral	0,46	neutral	0,06	neutral	0,22	neutral	0,26	5	neutral	0,96	neutral	0,37	neutral	-2	deleterious	0,61	low_impact	-2,13	medium_impact	0,42	low_impact	-2,16	0,29	0,8	32,6	72,72	N	0,34	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8226	8226	T	C	MI.6557	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	641	214	I	T	aTt/aCt	1,91	0,94	0	probably_damaging	0,99	neutral	0,44	neutral	1,97	neutral	-1,34	neutral	-1,17	neutral_impact	0,65	neutral	0,79	neutral	0,91	deleterious	2,3	18,17	0,44	0,55	neutral	0,35	neutral	0,37	neutral	0,31	neutral	0,46	1	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,69	low_impact	-2,58	medium_impact	0,15	medium_impact	-0,5	0,41	0,8	32,6	72,72	N	0,31	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8226	8226	T	A	MI.6558	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	641	214	I	N	aTt/aAt	1,91	0,94	0	probably_damaging	1	neutral	0,38	neutral	1,9	deleterious	-3,23	deleterious	-3,98	medium_impact	2,24	damaging	0,58	neutral	0,43	deleterious	4,71	24,6	0,37	0,5	disease	0,66	disease	0,73	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,78	low_impact	-3,52	medium_impact	0,09	medium_impact	1	0,51	0,8	32,6	72,72	N	0,33	N	0,83	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8226	8226	T	G	MI.6559	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	641	214	I	S	aTt/aGt	1,91	0,94	0	probably_damaging	0,99	neutral	0,48	neutral	1,93	neutral	-2,09	deleterious	-2,83	low_impact	1,9	neutral	0,66	neutral	0,71	deleterious	4,46	24,2	0,39	0,5	neutral	0,49	disease	0,71	disease	0,6	disease	0,7	4	deleterious	0,99	neutral	0,25	neutral	-2	deleterious	0,74	low_impact	-2,58	medium_impact	0,19	medium_impact	0,68	0,39	0,8	32,6	72,72	N	0,31	N	0,63	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8836	8836	A	G	MI.656	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	310	104	M	V	Atg/Gtg	-10,05	0	0,01	possibly_damaging	0,87	neutral	0,07	neutral	4,29	neutral	-1,23	neutral	-2,46	low_impact	1,73	neutral	0,9	neutral	0,51	deleterious	2,69	20,8	0,55	0,65	disease	0,53	disease	0,63	disease	0,63	disease	0,71	4	neutral	0,97	neutral	0,1	neutral	-3	deleterious	0,65	low_impact	-1,54	medium_impact	-0,34	medium_impact	0,39	0,58	0,9	48,23	8,5	N	0,49	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	A8836G	LHON	+	-	Reported	2
chrM	8227	8227	T	G	MI.6560	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	642	214	I	M	atT/atG	3,06	0,95	0,01	probably_damaging	1	neutral	0,24	neutral	1,94	neutral	-0,99	neutral	-1,27	low_impact	1,5	damaging	0,59	neutral	0,41	deleterious	3,64	23,2	0,64	0,7	neutral	0,3	neutral	0,43	disease	0,59	neutral	0,5	0	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,67	low_impact	-3,52	medium_impact	-0,07	medium_impact	0,3	0,55	0,8	32,6	72,72	N	0,44	N	0,66	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8227	8227	T	A	MI.6561	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	642	214	I	M	atT/atA	3,06	0,95	0,01	probably_damaging	1	neutral	0,24	neutral	1,94	neutral	-0,99	neutral	-1,27	low_impact	1,5	damaging	0,59	neutral	0,41	deleterious	3,91	23,5	0,64	0,7	neutral	0,3	neutral	0,43	disease	0,59	neutral	0,5	0	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,67	low_impact	-3,52	medium_impact	-0,07	medium_impact	0,3	0,55	0,8	32,6	72,72	N	0,44	N	0,66	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8228	8228	C	T	MI.6562	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	643	215	P	S	Ccc/Tcc	-9,16	0	0	probably_damaging	1	neutral	0,66	neutral	2,11	neutral	0,76	deleterious	-6,35	neutral_impact	-0,3	damaging	0,42	neutral	0,31	deleterious	2,86	21,7	0,59	0,65	neutral	0,28	neutral	0,35	neutral	0,13	neutral	0,44	1	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,7	low_impact	-3,52	medium_impact	0,36	low_impact	-1,39	0,19	0,8	23,35	40,36	N	0,42	N	0,28	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8228	8228	C	A	MI.6563	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	643	215	P	T	Ccc/Acc	-9,16	0	0	probably_damaging	1	neutral	0,56	neutral	1,95	neutral	-0,55	deleterious	-6,32	low_impact	1,25	damaging	0,38	damaging	0,21	deleterious	3,76	23,3	0,42	0,55	neutral	0,28	disease	0,54	neutral	0,17	neutral	0,46	1	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,72	low_impact	-3,52	medium_impact	0,26	medium_impact	0,07	0,65	0,8	23,35	40,36	N	0,44	N	0,67	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8228	8228	C	G	MI.6564	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	643	215	P	A	Ccc/Gcc	-9,16	0	0	probably_damaging	0,99	neutral	0,74	neutral	1,92	neutral	-1,07	deleterious	-6,53	medium_impact	2,22	damaging	0,38	damaging	0,14	deleterious	3,24	22,8	0,48	0,55	neutral	0,26	disease	0,54	neutral	0,49	neutral	0,5	0	deleterious	0,99	neutral	0,38	deleterious	1	deleterious	0,7	low_impact	-2,58	medium_impact	0,46	medium_impact	0,98	0,73	0,85	23,35	40,36	N	0,41	N	0,54	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8229	8229	C	T	MI.6565	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	644	215	P	L	cCc/cTc	2,83	0,98	0	probably_damaging	1	neutral	0,77	neutral	1,87	neutral	-2,42	deleterious	-8,34	medium_impact	2,02	damaging	0,29	damaging	0,02	deleterious	4,53	24,3	0,43	0,55	disease	0,56	disease	0,75	neutral	0,49	disease	0,58	2	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,76	low_impact	-3,52	medium_impact	0,5	medium_impact	0,79	0,72	0,85	23,35	40,36	P	0,62	P	0,89	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8229	8229	C	A	MI.6566	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	644	215	P	H	cCc/cAc	2,83	0,98	0	probably_damaging	1	neutral	0,59	neutral	1,87	neutral	-2,26	deleterious	-7,45	medium_impact	2,92	damaging	0,29	damaging	0,02	deleterious	4,14	23,8	0,4	0,5	disease	0,73	disease	0,75	disease	0,57	disease	0,68	4	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,79	low_impact	-3,52	medium_impact	0,29	medium_impact	1,63	0,66	0,8	23,35	40,36	P	0,67	P	0,86	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8229	8229	C	G	MI.6567	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	644	215	P	R	cCc/cGc	2,83	0,98	0	probably_damaging	1	neutral	0,49	neutral	1,9	neutral	-1,43	deleterious	-7,51	medium_impact	2,92	damaging	0,22	damaging	0,02	deleterious	3,78	23,4	0,33	0,5	disease	0,58	disease	0,85	disease	0,61	disease	0,74	5	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,81	low_impact	-3,52	medium_impact	0,2	medium_impact	1,63	0,64	0,8	23,35	40,36	P	0,72	P	0,93	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8231	8231	C	G	MI.6568	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	646	216	L	V	Cta/Gta	-14,47	0	0	possibly_damaging	0,89	neutral	0,54	neutral	1,94	neutral	-1,07	neutral	-2,15	low_impact	0,83	damaging	0,51	damaging	0,28	deleterious	2,4	18,84	0,56	0,6	disease	0,72	neutral	0,33	neutral	0,1	disease	0,63	3	neutral	0,88	neutral	0,33	neutral	-3	deleterious	0,67	low_impact	-1,57	medium_impact	0,24	medium_impact	-0,33	0,78	0,85	71,37	19,32	N	0,37	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8231	8231	C	A	MI.6569	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	646	216	L	M	Cta/Ata	-14,47	0	0	probably_damaging	0,99	neutral	0,23	neutral	1,88	neutral	-1,87	neutral	-1,64	low_impact	1,03	damaging	0,5	neutral	0,3	deleterious	2,76	21,2	0,44	0,55	disease	0,81	neutral	0,15	neutral	0,08	neutral	0,39	2	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,71	low_impact	-2,58	medium_impact	-0,09	medium_impact	-0,14	0,81	0,85	71,37	19,32	N	0,44	N	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8836	8836	A	T	MI.657	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	310	104	M	L	Atg/Ttg	-10,05	0	0,01	possibly_damaging	0,81	neutral	1	neutral	5	neutral	2,39	neutral	-1,04	neutral_impact	-1,71	neutral	0,81	neutral	0,65	deleterious	0,64	8,41	0,42	0,65	disease	0,57	neutral	0,21	neutral	0,38	neutral	0,48	0	neutral	0,81	deleterious	0,6	neutral	-3	deleterious	0,51	low_impact	-1,35	high_impact	1,98	low_impact	-2,56	0,55	0,9	48,23	8,5	N	0,3	N	0,93	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8232	8232	T	A	MI.6570	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	647	216	L	Q	cTa/cAa	-0,17	0	0	probably_damaging	0,99	neutral	0,3	neutral	1,92	neutral	-0,2	deleterious	-5,31	low_impact	1,2	damaging	0,36	damaging	0,08	deleterious	4,22	23,9	0,24	0,45	disease	0,66	disease	0,53	neutral	0,25	neutral	0,49	0	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,76	low_impact	-2,58	medium_impact	0	medium_impact	0,02	0,77	0,85	71,37	19,32	N	0,45	N	0,96	disease_causing	0,95	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8232	8232	T	C	MI.6571	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	647	216	L	P	cTa/cCa	-0,17	0	0	probably_damaging	1	neutral	0,23	neutral	1,96	neutral	-1,52	deleterious	-6,1	neutral_impact	-0,26	damaging	0,13	damaging	0,06	deleterious	4,05	23,7	0,36	0,5	disease	0,58	disease	0,71	neutral	0,24	disease	0,51	0	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,79	low_impact	-3,52	medium_impact	-0,09	low_impact	-1,35	0,53	0,8	71,37	19,32	P	0,68	P	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8232	8232	T	G	MI.6572	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	647	216	L	R	cTa/cGa	-0,17	0	0	probably_damaging	0,99	neutral	0,35	neutral	1,91	neutral	-0,64	deleterious	-5,33	low_impact	1,48	damaging	0,16	damaging	0,06	deleterious	4,3	24	0,25	0,45	disease	0,53	disease	0,81	neutral	0,33	disease	0,69	4	deleterious	0,99	neutral	0,18	neutral	-2	deleterious	0,79	low_impact	-2,58	medium_impact	0,06	medium_impact	0,28	0,58	0,8	71,37	19,32	P	0,7	P	0,99	disease_causing	0,96	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8234	8234	A	G	MI.6573	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	649	217	K	E	Aaa/Gaa	-0,63	0	0	possibly_damaging	0,87	neutral	0,54	neutral	2,09	neutral	0,69	neutral	-0,6	neutral_impact	0,35	neutral	0,69	neutral	0,63	deleterious	1,92	15,7	0,27	0,45	neutral	0,25	disease	0,6	neutral	0,26	neutral	0,45	1	neutral	0,85	neutral	0,34	neutral	-3	deleterious	0,66	low_impact	-1,49	medium_impact	0,24	medium_impact	-0,78	0,63	0,8	61,67	17,69	N	0,31	N	0,92	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8234	8234	A	C	MI.6574	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	649	217	K	Q	Aaa/Caa	-0,63	0	0	possibly_damaging	0,86	neutral	0,45	neutral	1,93	neutral	-0,87	neutral	-0,88	low_impact	1,18	neutral	0,78	neutral	0,62	deleterious	2,1	16,86	0,33	0,5	disease	0,58	neutral	0,41	neutral	0,19	disease	0,62	2	neutral	0,85	neutral	0,3	neutral	-3	deleterious	0,68	low_impact	-1,46	medium_impact	0,16	medium_impact	0	0,75	0,85	61,67	17,69	N	0,41	N	0,84	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8235	8235	A	C	MI.6575	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	650	217	K	T	aAa/aCa	0,06	0	0	probably_damaging	0,96	neutral	0,54	neutral	1,92	neutral	-1,11	neutral	-2,1	low_impact	1,38	neutral	0,73	neutral	0,46	deleterious	2,28	18,04	0,22	0,45	disease	0,59	neutral	0,45	neutral	0,34	disease	0,62	2	neutral	0,95	neutral	0,29	neutral	-2	deleterious	0,74	low_impact	-2,01	medium_impact	0,24	medium_impact	0,19	0,59	0,8	61,67	17,69	N	0,25	N	0,77	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8235	8235	A	T	MI.6576	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	650	217	K	M	aAa/aTa	0,06	0	0	probably_damaging	0,98	neutral	0,24	neutral	1,86	deleterious	-4,02	deleterious	-2,67	medium_impact	3,08	damaging	0,57	damaging	0,21	deleterious	3,81	23,4	0,18	0,45	disease	0,84	neutral	0,47	neutral	0,46	disease	0,64	3	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,75	low_impact	-2,3	medium_impact	-0,07	medium_impact	1,78	0,55	0,8	61,67	17,69	N	0,36	N	0,81	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8236	8236	A	C	MI.6577	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	651	217	K	N	aaA/aaC	0,98	0	0	probably_damaging	0,98	neutral	0,45	neutral	1,97	neutral	-0,34	neutral	-1,21	neutral_impact	0,56	neutral	0,66	neutral	0,55	neutral	1,78	14,84	0,49	0,55	disease	0,57	neutral	0,13	neutral	0,16	neutral	0,33	3	neutral	0,97	neutral	0,24	neutral	-2	deleterious	0,69	low_impact	-2,3	medium_impact	0,16	medium_impact	-0,58	0,66	0,8	61,67	17,69	N	0,43	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8236	8236	A	T	MI.6578	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	651	217	K	N	aaA/aaT	0,98	0	0	probably_damaging	0,98	neutral	0,45	neutral	1,97	neutral	-0,34	neutral	-1,21	neutral_impact	0,56	neutral	0,66	neutral	0,55	deleterious	1,83	15,19	0,49	0,55	disease	0,57	neutral	0,13	neutral	0,16	neutral	0,33	3	neutral	0,97	neutral	0,24	neutral	-2	deleterious	0,69	low_impact	-2,3	medium_impact	0,16	medium_impact	-0,58	0,66	0,8	61,67	17,69	N	0,43	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8237	8237	A	G	MI.6579	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	652	218	I	V	Atc/Gtc	-0,17	0	0	benign	0	neutral	0,5	neutral	2,01	neutral	0,55	neutral	0,06	neutral_impact	-0,49	neutral	0,8	neutral	0,58	deleterious	0,02	2,81	0,76	0,8	neutral	0,43	neutral	0,14	neutral	0,24	neutral	0,28	4	neutral	0,5	deleterious	0,75	neutral	-6	neutral	0,11	high_impact	2,08	medium_impact	0,21	low_impact	-1,57	0,58	0,8	34,36	63,36	N	0,37	N	0,5	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8836	8836	A	C	MI.658	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	310	104	M	L	Atg/Ctg	-10,05	0	0,01	possibly_damaging	0,81	neutral	1	neutral	5	neutral	2,39	neutral	-1,04	neutral_impact	-1,71	neutral	0,81	neutral	0,65	deleterious	0,58	8,01	0,42	0,65	disease	0,57	neutral	0,21	neutral	0,38	neutral	0,48	0	neutral	0,81	deleterious	0,6	neutral	-3	deleterious	0,51	low_impact	-1,35	high_impact	1,98	low_impact	-2,56	0,55	0,9	48,23	8,5	N	0,3	N	0,93	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8237	8237	A	T	MI.6580	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	652	218	I	F	Atc/Ttc	-0,17	0	0	benign	0,14	neutral	0,72	neutral	2	neutral	0,17	neutral	1,24	neutral_impact	-1,36	neutral	0,71	neutral	0,93	deleterious	0,65	8,52	0,64	0,7	neutral	0,27	neutral	0,27	neutral	0,12	neutral	0,42	2	neutral	0,16	deleterious	0,79	neutral	-6	neutral	0,23	medium_impact	0,01	medium_impact	0,43	low_impact	-2,38	0,65	0,8	34,36	63,36	N	0,37	N	0,42	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8237	8237	A	C	MI.6581	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	652	218	I	L	Atc/Ctc	-0,17	0	0	benign	0,01	neutral	0,67	neutral	2,02	neutral	0,9	neutral	-0,12	neutral_impact	-0,44	neutral	0,7	neutral	0,62	deleterious	0,73	8,99	0,68	0,7	neutral	0,29	neutral	0,22	neutral	0,19	neutral	0,39	2	neutral	0,31	deleterious	0,83	neutral	-6	neutral	0,1	medium_impact	1,14	medium_impact	0,38	low_impact	-1,52	0,59	0,8	34,36	63,36	N	0,43	N	0,44	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8238	8238	T	A	MI.6582	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	653	218	I	N	aTc/aAc	-2,94	0	0	possibly_damaging	0,5	neutral	0,33	neutral	2,08	neutral	2,06	neutral	3,12	neutral_impact	-2,04	neutral	0,73	neutral	0,88	neutral	1,66	14,17	0,47	0,55	neutral	0,26	neutral	0,3	neutral	0,16	neutral	0,43	1	neutral	0,64	neutral	0,42	neutral	-3	neutral	0,41	medium_impact	-0,72	medium_impact	0,04	low_impact	-3,02	0,49	0,8	34,36	63,36	N	0,46	N	0,19	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8238	8238	T	G	MI.6583	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	653	218	I	S	aTc/aGc	-2,94	0	0	benign	0,18	neutral	0,43	neutral	2,09	neutral	2,21	neutral	1,63	neutral_impact	-1,78	neutral	0,72	neutral	0,71	neutral	1,21	11,82	0,46	0,55	neutral	0,25	neutral	0,26	neutral	0,16	neutral	0,41	2	neutral	0,49	deleterious	0,63	neutral	-6	neutral	0,16	medium_impact	-0,11	medium_impact	0,14	low_impact	-2,77	0,39	0,8	34,36	63,36	N	0,45	N	0,5	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8238	8238	T	C	MI.6584	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	653	218	I	T	aTc/aCc	-2,94	0	0	benign	0,06	neutral	0,41	neutral	2,06	neutral	1,73	neutral	0,98	neutral_impact	-0,82	neutral	0,79	neutral	0,8	deleterious	0,3	5,7	0,51	0,6	neutral	0,31	neutral	0,11	neutral	0,15	neutral	0,28	4	neutral	0,55	deleterious	0,68	neutral	-6	neutral	0,12	medium_impact	0,39	medium_impact	0,12	low_impact	-1,87	0,39	0,8	34,36	63,36	N	0,48	N	0,45	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8239	8239	C	A	MI.6585	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	654	218	I	M	atC/atA	0,29	0	0	benign	0,32	neutral	0,23	neutral	1,99	neutral	-0,72	neutral	0,57	neutral_impact	-0,14	neutral	0,69	neutral	0,46	deleterious	2,19	17,41	0,78	0,8	disease	0,58	neutral	0,15	neutral	0,13	neutral	0,36	3	neutral	0,72	neutral	0,46	neutral	-6	neutral	0,27	medium_impact	-0,42	medium_impact	-0,09	low_impact	-1,24	0,75	0,85	34,36	63,36	N	0,53	P	0,63	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8239	8239	C	G	MI.6586	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	654	218	I	M	atC/atG	0,29	0	0	benign	0,32	neutral	0,23	neutral	1,99	neutral	-0,72	neutral	0,57	neutral_impact	-0,14	neutral	0,69	neutral	0,46	neutral	1,77	14,8	0,78	0,8	disease	0,58	neutral	0,15	neutral	0,13	neutral	0,36	3	neutral	0,72	neutral	0,46	neutral	-6	neutral	0,27	medium_impact	-0,42	medium_impact	-0,09	low_impact	-1,24	0,75	0,85	34,36	63,36	N	0,53	P	0,63	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8240	8240	T	C	MI.6587	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	655	219	F	L	Ttt/Ctt	-1,09	0	0	probably_damaging	0,98	neutral	0,69	neutral	1,23	deleterious	-4,45	deleterious	-5,33	medium_impact	3,48	damaging	0,31	neutral	0,48	deleterious	4,16	23,8	0,16	0,45	disease	0,77	disease	0,79	disease	0,76	disease	0,78	6	neutral	0,98	neutral	0,36	deleterious	1	deleterious	0,82	low_impact	-2,3	medium_impact	0,4	high_impact	2,16	0,54	0,8	67,84	19,2	P	0,68	P	0,8	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8240	8240	T	G	MI.6588	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	655	219	F	V	Ttt/Gtt	-1,09	0	0	probably_damaging	1	neutral	0,49	neutral	1,21	deleterious	-5,39	deleterious	-6,24	high_impact	4,72	damaging	0,3	neutral	0,4	deleterious	4,1	23,7	0,14	0,4	disease	0,71	disease	0,88	disease	0,75	disease	0,81	6	deleterious	0,99	neutral	0,25	deleterious	2	deleterious	0,84	low_impact	-3,52	medium_impact	0,2	high_impact	3,32	0,35	0,8	67,84	19,2	P	0,75	P	0,92	polymorphism	0,99	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8240	8240	T	A	MI.6589	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	655	219	F	I	Ttt/Att	-1,09	0	0	probably_damaging	0,99	neutral	0,4	neutral	1,2	deleterious	-5,85	deleterious	-5,41	high_impact	4,38	damaging	0,33	neutral	0,51	deleterious	4,5	24,3	0,12	0,4	disease	0,58	disease	0,82	disease	0,77	disease	0,78	6	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-2,58	medium_impact	0,11	high_impact	3	0,34	0,8	67,84	19,2	P	0,69	P	0,88	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8837	8837	T	C	MI.659	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	311	104	M	T	aTg/aCg	0,36	0,03	0	probably_damaging	0,94	deleterious	0,04	neutral	4,24	neutral	-2,57	deleterious	-4,28	medium_impact	2,62	neutral	0,87	neutral	0,52	deleterious	2,9	21,9	0,37	0,65	disease	0,71	disease	0,65	disease	0,64	disease	0,71	4	deleterious	0,99	neutral	0,05	deleterious	5	deleterious	0,78	low_impact	-1,89	medium_impact	-0,49	medium_impact	1,15	0,44	0,9	48,23	8,5	N	0,39	N	0,97	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8241	8241	T	A	MI.6590	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	656	219	F	Y	tTt/tAt	7,44	1	0	probably_damaging	0,98	neutral	1	neutral	1,72	neutral	-0,76	deleterious	-2,79	medium_impact	2,04	damaging	0,33	neutral	0,35	deleterious	4,34	24,1	0,13	0,4	neutral	0,37	disease	0,73	disease	0,62	disease	0,51	0	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,77	low_impact	-2,3	high_impact	1,86	medium_impact	0,81	0,47	0,8	67,84	19,2	P	0,76	P	0,76	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8241	8241	T	C	MI.6591	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	656	219	F	S	tTt/tCt	7,44	1	0	probably_damaging	1	neutral	0,47	neutral	1,2	deleterious	-5,9	deleterious	-6,71	high_impact	4,03	damaging	0,28	neutral	0,5	deleterious	4,38	24,1	0,08	0,35	disease	0,89	disease	0,85	disease	0,76	disease	0,84	7	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,87	low_impact	-3,52	medium_impact	0,18	high_impact	2,67	0,24	0,8	67,84	19,2	P	0,93	P	0,96	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8241	8241	T	G	MI.6592	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	656	219	F	C	tTt/tGt	7,44	1	0	probably_damaging	1	neutral	0,18	neutral	1,2	deleterious	-6,62	deleterious	-7,08	high_impact	4,72	damaging	0,3	neutral	0,39	deleterious	4,23	23,9	0,12	0,4	disease	0,95	disease	0,83	disease	0,8	disease	0,87	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,52	medium_impact	-0,16	high_impact	3,32	0,19	0,8	67,84	19,2	P	0,8	P	1	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8242	8242	T	A	MI.6593	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	657	219	F	L	ttT/ttA	7,44	1	0	probably_damaging	0,98	neutral	0,69	neutral	1,23	deleterious	-4,45	deleterious	-5,33	medium_impact	3,48	damaging	0,31	neutral	0,48	deleterious	4,58	24,4	0,16	0,45	disease	0,77	disease	0,79	disease	0,76	disease	0,78	6	neutral	0,98	neutral	0,36	deleterious	1	deleterious	0,82	low_impact	-2,3	medium_impact	0,4	high_impact	2,16	0,54	0,8	67,84	19,2	P	0,81	P	0,8	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8242	8242	T	G	MI.6594	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	657	219	F	L	ttT/ttG	7,44	1	0	probably_damaging	0,98	neutral	0,69	neutral	1,23	deleterious	-4,45	deleterious	-5,33	medium_impact	3,48	damaging	0,31	neutral	0,48	deleterious	4,5	24,3	0,16	0,45	disease	0,77	disease	0,79	disease	0,76	disease	0,78	6	neutral	0,98	neutral	0,36	deleterious	1	deleterious	0,82	low_impact	-2,3	medium_impact	0,4	high_impact	2,16	0,54	0,8	67,84	19,2	P	0,81	P	0,8	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8243	8243	G	A	MI.6595	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	658	220	E	K	Gaa/Aaa	-5,01	0	0	probably_damaging	0,94	neutral	0,3	neutral	2,53	neutral	-1,24	deleterious	-2,76	neutral_impact	-0,02	damaging	0,48	neutral	0,33	deleterious	4,53	24,3	0,42	0,55	neutral	0,25	disease	0,74	neutral	0,47	disease	0,56	1	neutral	0,95	neutral	0,18	neutral	-2	deleterious	0,73	low_impact	-1,83	medium_impact	0	low_impact	-1,12	0,75	0,85	NA	NA	N	0,35	N	0,99	polymorphism	0,97	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8243	8243	G	C	MI.6596	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	658	220	E	Q	Gaa/Caa	-5,01	0	0	probably_damaging	0,95	neutral	0,3	neutral	2,5	neutral	-1,49	neutral	-2,12	low_impact	0,84	damaging	0,59	neutral	0,69	deleterious	2,27	17,99	0,53	0,6	neutral	0,37	neutral	0,41	neutral	0,37	neutral	0,39	2	neutral	0,95	neutral	0,18	neutral	-2	deleterious	0,69	low_impact	-1,91	medium_impact	0	medium_impact	-0,32	0,68	0,85	NA	NA	N	0,39	N	0,76	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8244	8244	A	G	MI.6597	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	659	220	E	G	gAa/gGa	6,06	1	0	probably_damaging	0,98	neutral	0,33	neutral	2,43	neutral	-2,28	deleterious	-5,48	low_impact	1,32	damaging	0,52	neutral	0,51	deleterious	4,41	24,1	0,38	0,5	disease	0,59	disease	0,6	disease	0,63	disease	0,67	3	neutral	0,98	neutral	0,18	neutral	-2	deleterious	0,74	low_impact	-2,3	medium_impact	0,04	medium_impact	0,13	0,49	0,8	NA	NA	N	0,51	P	0,6	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8244	8244	A	C	MI.6598	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	659	220	E	A	gAa/gCa	6,06	1	0	probably_damaging	0,96	neutral	0,52	neutral	2,49	neutral	-1,68	deleterious	-4,48	neutral_impact	0,28	damaging	0,54	neutral	0,48	deleterious	3,84	23,4	0,35	0,5	neutral	0,45	disease	0,55	disease	0,6	disease	0,65	3	neutral	0,96	neutral	0,28	neutral	-2	deleterious	0,72	low_impact	-2,01	medium_impact	0,22	medium_impact	-0,84	0,68	0,85	NA	NA	N	0,47	N	0,65	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8244	8244	A	T	MI.6599	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	659	220	E	V	gAa/gTa	6,06	1	0	probably_damaging	0,97	neutral	0,5	neutral	2,45	neutral	-2,96	deleterious	-5,01	neutral_impact	0,14	damaging	0,51	neutral	0,42	deleterious	4,4	24,1	0,28	0,45	disease	0,68	disease	0,77	disease	0,65	disease	0,69	4	neutral	0,97	neutral	0,27	neutral	-2	deleterious	0,78	low_impact	-2,13	medium_impact	0,21	medium_impact	-0,97	0,77	0,85	NA	NA	N	0,48	N	0,81	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8555	8555	T	C	MI.66	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	29	10	I	T	aTt/aCt	-3,11	0	0	benign	0	neutral	0,12	neutral	4,73	neutral	-0,08	neutral	-0,17	neutral_impact	0,74	neutral	0,95	neutral	0,96	deleterious	0,03	2,91	0,39	0,65	neutral	0,21	neutral	0,29	neutral	0,23	neutral	0,43	1	neutral	0,88	deleterious	0,56	neutral	-6	neutral	0,08	high_impact	2,09	medium_impact	-0,2	medium_impact	-0,46	0,24	0,9	27,43	16,7	N	0,47	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8837	8837	T	A	MI.660	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	311	104	M	K	aTg/aAg	0,36	0,03	0	probably_damaging	0,94	deleterious	0	neutral	4,22	deleterious	-3,92	deleterious	-4,67	medium_impact	2,62	neutral	0,85	neutral	0,39	deleterious	4,01	23,6	0,13	0,65	disease	0,85	disease	0,82	disease	0,71	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,83	low_impact	-1,89	low_impact	-1,4	medium_impact	1,15	0,4	0,9	48,23	8,5	N	0,31	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8245	8245	A	T	MI.6600	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	660	220	E	D	gaA/gaT	8,59	1	0	possibly_damaging	0,8	neutral	0,22	neutral	2,52	neutral	-0,14	neutral	-2,36	neutral_impact	0,08	damaging	0,56	neutral	0,39	deleterious	3,9	23,5	0,43	0,55	neutral	0,26	disease	0,54	neutral	0,48	neutral	0,46	1	neutral	0,87	neutral	0,21	neutral	-3	deleterious	0,59	low_impact	-1,28	medium_impact	-0,1	low_impact	-1,03	0,82	0,85	NA	NA	P	0,59	P	0,82	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8245	8245	A	C	MI.6601	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	660	220	E	D	gaA/gaC	8,59	1	0	possibly_damaging	0,8	neutral	0,22	neutral	2,52	neutral	-0,14	neutral	-2,36	neutral_impact	0,08	damaging	0,56	neutral	0,39	deleterious	3,75	23,3	0,43	0,55	neutral	0,26	disease	0,54	neutral	0,48	neutral	0,46	1	neutral	0,87	neutral	0,21	neutral	-3	deleterious	0,59	low_impact	-1,28	medium_impact	-0,1	low_impact	-1,03	0,82	0,85	NA	NA	P	0,58	P	0,82	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8246	8246	A	C	MI.6602	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	661	221	M	L	Ata/Cta	0,75	0,14	0	possibly_damaging	0,7	neutral	0,67	neutral	2,64	neutral	1,27	neutral	-0,69	neutral_impact	-0,8	neutral	0,82	neutral	0,75	neutral	-0,8	0,04	0,53	0,6	neutral	0,39	neutral	0,1	neutral	0,17	neutral	0,06	9	neutral	0,64	deleterious	0,49	neutral	-3	neutral	0,41	low_impact	-1,06	medium_impact	0,38	low_impact	-1,86	0,71	0,85	33,04	90,86	N	0,39	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8246	8246	A	T	MI.6603	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	661	221	M	L	Ata/Tta	0,75	0,14	0	possibly_damaging	0,7	neutral	0,67	neutral	2,64	neutral	1,27	neutral	-0,69	neutral_impact	-0,8	neutral	0,82	neutral	0,75	neutral	-0,73	0,06	0,53	0,6	neutral	0,39	neutral	0,1	neutral	0,17	neutral	0,06	9	neutral	0,64	deleterious	0,49	neutral	-3	neutral	0,41	low_impact	-1,06	medium_impact	0,38	low_impact	-1,86	0,71	0,85	33,04	90,86	N	0,39	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8246	8246	A	G	MI.6604	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	661	221	M	V	Ata/Gta	0,75	0,14	0	possibly_damaging	0,79	neutral	0,52	neutral	2,63	neutral	0,97	neutral	-0,53	neutral_impact	-0,52	neutral	0,83	neutral	0,82	neutral	-1,8	0	0,4	0,5	disease	0,57	neutral	0,18	neutral	0,2	neutral	0,08	8	neutral	0,76	neutral	0,37	neutral	-3	deleterious	0,5	low_impact	-1,26	medium_impact	0,22	low_impact	-1,59	0,76	0,85	33,04	90,86	N	0,36	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8247	8247	T	C	MI.6605	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	662	221	M	T	aTa/aCa	0,06	0	0	possibly_damaging	0,9	neutral	0,43	neutral	2,61	neutral	0,48	neutral	1,4	neutral_impact	0,65	neutral	0,82	neutral	0,85	neutral	-1,22	0,01	0,39	0,5	neutral	0,39	neutral	0,24	neutral	0,28	neutral	0,18	6	neutral	0,89	neutral	0,27	neutral	-3	deleterious	0,61	low_impact	-1,61	medium_impact	0,14	medium_impact	-0,5	0,31	0,8	33,04	90,86	N	0,32	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8247	8247	T	A	MI.6606	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	662	221	M	K	aTa/aAa	0,06	0	0	possibly_damaging	0,9	neutral	0,37	neutral	2,64	neutral	0,93	neutral	1,51	low_impact	1,2	neutral	0,8	neutral	0,83	deleterious	0,15	4,19	0,32	0,5	neutral	0,4	neutral	0,48	neutral	0,5	neutral	0,32	4	neutral	0,9	neutral	0,24	neutral	-3	deleterious	0,63	low_impact	-1,61	medium_impact	0,08	medium_impact	0,02	0,68	0,85	33,04	90,86	N	0,31	N	0,27	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8248	8248	A	T	MI.6607	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	663	221	M	I	atA/atT	-0,17	0	0	possibly_damaging	0,84	neutral	0,41	neutral	2,6	neutral	0,71	neutral	-0,76	neutral_impact	-1,01	neutral	0,82	neutral	0,84	neutral	-0,13	1,52	0,5	0,6	disease	0,66	neutral	0,2	neutral	0,17	neutral	0,15	7	neutral	0,84	neutral	0,29	neutral	-3	deleterious	0,59	low_impact	-1,39	medium_impact	0,12	low_impact	-2,05	0,77	0,85	33,04	90,86	N	0,42	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8248	8248	A	C	MI.6608	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	663	221	M	I	atA/atC	-0,17	0	0	possibly_damaging	0,84	neutral	0,41	neutral	2,6	neutral	0,71	neutral	-0,76	neutral_impact	-1,01	neutral	0,82	neutral	0,84	neutral	-0,31	0,64	0,5	0,6	disease	0,66	neutral	0,2	neutral	0,17	neutral	0,15	7	neutral	0,84	neutral	0,29	neutral	-3	deleterious	0,59	low_impact	-1,39	medium_impact	0,12	low_impact	-2,05	0,77	0,85	33,04	90,86	N	0,42	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8249	8249	G	T	MI.6609	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	664	222	G	W	Ggg/Tgg	-0,63	0	0	probably_damaging	1	neutral	0,28	neutral	2,53	neutral	-2,68	neutral	11,25	low_impact	0,9	neutral	0,72	neutral	0,77	neutral	1,79	14,94	0,13	0,4	disease	0,63	neutral	0,11	neutral	0,4	neutral	0,05	9	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,71	low_impact	-3,52	medium_impact	-0,02	medium_impact	-0,26	0,38	0,8	28,63	77,15	N	0,45	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8838	8838	G	T	MI.661	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	312	104	M	I	atG/atT	7,53	0,97	0	probably_damaging	0,91	neutral	0,18	neutral	4,39	neutral	0,02	neutral	-2,09	neutral_impact	0,5	neutral	0,85	neutral	0,57	deleterious	2,48	19,35	0,51	0,65	disease	0,53	disease	0,63	neutral	0,45	neutral	0,36	3	neutral	0,95	neutral	0,14	neutral	-2	deleterious	0,72	low_impact	-1,71	medium_impact	-0,08	medium_impact	-0,67	0,7	0,9	48,23	8,5	N	0,48	N	0,91	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8249	8249	G	C	MI.6610	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	664	222	G	R	Ggg/Cgg	-0,63	0	0	probably_damaging	1	neutral	0,34	neutral	2,59	neutral	-0,85	neutral	-0,86	neutral_impact	0,2	damaging	0,6	neutral	0,51	deleterious	2,97	22,1	0,13	0,4	neutral	0,39	disease	0,77	disease	0,56	disease	0,67	3	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,81	low_impact	-3,52	medium_impact	0,05	medium_impact	-0,92	0,47	0,8	28,63	77,15	N	0,33	N	0,78	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8250	8250	G	A	MI.6611	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	665	222	G	E	gGg/gAg	5,36	1	0	probably_damaging	1	neutral	0,28	neutral	2,6	neutral	-0,71	neutral	-0,83	neutral_impact	-0,2	neutral	0,64	neutral	0,54	deleterious	3,29	22,8	0,18	0,45	neutral	0,37	disease	0,68	disease	0,54	disease	0,59	2	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,77	low_impact	-3,52	medium_impact	-0,02	low_impact	-1,29	0,39	0,8	28,63	77,15	N	0,42	N	0,86	disease_causing	0,88	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8250	8250	G	C	MI.6612	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	665	222	G	A	gGg/gCg	5,36	1	0	probably_damaging	1	neutral	0,51	neutral	2,64	neutral	-0,1	neutral	-0,6	neutral_impact	-0,38	neutral	0,66	neutral	0,61	deleterious	2,24	17,79	0,21	0,45	neutral	0,32	neutral	0,37	neutral	0,29	neutral	0,15	7	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,72	low_impact	-3,52	medium_impact	0,21	low_impact	-1,46	0,38	0,8	28,63	77,15	N	0,44	N	0,49	disease_causing	0,74	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8250	8250	G	T	MI.6613	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	665	222	G	V	gGg/gTg	5,36	1	0	probably_damaging	1	neutral	0,53	neutral	2,63	neutral	-0,62	neutral	-0,82	neutral_impact	0,2	damaging	0,6	neutral	0,54	deleterious	4,09	23,7	0,15	0,4	neutral	0,3	disease	0,64	neutral	0,41	neutral	0,48	0	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,74	low_impact	-3,52	medium_impact	0,23	medium_impact	-0,92	0,41	0,8	28,63	77,15	N	0,41	N	0,7	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8252	8252	C	T	MI.6614	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	667	223	P	S	Ccc/Tcc	3,52	1	0	benign	0,17	neutral	0,51	neutral	2,66	neutral	0,05	neutral	2,77	neutral_impact	-1,86	neutral	0,84	neutral	0,85	neutral	-0,29	0,72	0,46	0,55	neutral	0,37	neutral	0,04	neutral	0,17	neutral	0,05	9	neutral	0,39	deleterious	0,67	neutral	-6	neutral	0,21	medium_impact	-0,08	medium_impact	0,21	low_impact	-2,85	0,15	0,8	32,16	9,43	N	0,49	N	0,04	polymorphism	0,78	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8252	8252	C	G	MI.6615	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	667	223	P	A	Ccc/Gcc	3,52	1	0	benign	0,01	neutral	0,59	neutral	2,68	neutral	0,35	neutral	1,41	neutral_impact	-1,24	neutral	0,87	neutral	0,85	deleterious	-0,03	2,34	0,36	0,5	neutral	0,24	neutral	0,14	neutral	0,37	neutral	0,1	8	neutral	0,4	deleterious	0,79	neutral	-6	neutral	0,09	medium_impact	1,14	medium_impact	0,29	low_impact	-2,27	0,83	0,9	32,16	9,43	N	0,45	N	0,29	polymorphism	0,85	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8252	8252	C	A	MI.6616	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	667	223	P	T	Ccc/Acc	3,52	1	0	benign	0,17	neutral	0,46	neutral	2,63	neutral	-0,32	neutral	2,01	neutral_impact	-1,24	neutral	0,82	neutral	0,81	neutral	-0,48	0,25	0,43	0,55	neutral	0,26	neutral	0,11	neutral	0,39	neutral	0,05	9	neutral	0,45	deleterious	0,65	neutral	-6	neutral	0,21	medium_impact	-0,08	medium_impact	0,17	low_impact	-2,27	0,72	0,85	32,16	9,43	N	0,52	P	0,36	polymorphism	0,78	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8253	8253	C	G	MI.6617	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	668	223	P	R	cCc/cGc	2,44	1	0	possibly_damaging	0,6	neutral	0,41	neutral	2,62	neutral	-0,61	neutral	-0,16	neutral_impact	-0,55	neutral	0,79	neutral	0,76	neutral	1,24	11,96	0,37	0,5	neutral	0,23	neutral	0,5	disease	0,58	disease	0,58	2	neutral	0,63	neutral	0,41	neutral	-3	deleterious	0,47	medium_impact	-0,89	medium_impact	0,12	low_impact	-1,62	0,68	0,85	32,16	9,43	N	0,36	N	0,71	polymorphism	0,96	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8253	8253	C	T	MI.6618	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	668	223	P	L	cCc/cTc	2,44	1	0	benign	0,17	neutral	0,69	neutral	2,68	neutral	-0,09	neutral	0,4	neutral_impact	-0,9	neutral	0,9	neutral	0,8	deleterious	1,83	15,15	0,49	0,55	neutral	0,35	neutral	0,29	neutral	0,42	neutral	0,14	7	neutral	0,19	deleterious	0,76	neutral	-6	neutral	0,24	medium_impact	-0,08	medium_impact	0,4	low_impact	-1,95	0,74	0,85	32,16	9,43	N	0,42	N	0,8	disease_causing	0,91	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8253	8253	C	A	MI.6619	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	668	223	P	H	cCc/cAc	2,44	1	0	possibly_damaging	0,82	neutral	0,55	neutral	2,57	neutral	-1,8	neutral	-0,3	neutral_impact	-0,34	neutral	0,82	neutral	0,75	deleterious	4,09	23,7	0,38	0,5	neutral	0,46	neutral	0,29	disease	0,62	neutral	0,14	7	neutral	0,79	neutral	0,37	neutral	-3	deleterious	0,59	low_impact	-1,33	medium_impact	0,25	low_impact	-1,42	0,68	0,85	32,16	9,43	N	0,35	N	0,73	polymorphism	0,98	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8838	8838	G	C	MI.662	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	312	104	M	I	atG/atC	7,53	0,97	0	probably_damaging	0,91	neutral	0,18	neutral	4,39	neutral	0,02	neutral	-2,09	neutral_impact	0,5	neutral	0,85	neutral	0,57	deleterious	2,38	18,69	0,51	0,65	disease	0,53	disease	0,63	neutral	0,45	neutral	0,36	3	neutral	0,95	neutral	0,14	neutral	-2	deleterious	0,72	low_impact	-1,71	medium_impact	-0,08	medium_impact	-0,67	0,7	0,9	48,23	8,5	N	0,47	N	0,91	polymorphism	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8255	8255	G	T	MI.6620	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	670	224	V	L	Gta/Tta	-10,75	0	0	probably_damaging	0,96	neutral	0,7	neutral	2,57	neutral	-0,19	neutral	-0,12	neutral_impact	-0,34	neutral	0,88	neutral	0,7	deleterious	2,35	18,52	0,47	0,55	neutral	0,22	neutral	0,13	neutral	0,3	neutral	0,06	9	neutral	0,96	neutral	0,37	neutral	-2	deleterious	0,59	low_impact	-2,01	medium_impact	0,41	low_impact	-1,42	0,66	0,8	31,72	62,66	N	0,33	N	0,42	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8255	8255	G	C	MI.6621	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	670	224	V	L	Gta/Cta	-10,75	0	0	probably_damaging	0,96	neutral	0,7	neutral	2,57	neutral	-0,19	neutral	-0,12	neutral_impact	-0,34	neutral	0,88	neutral	0,7	deleterious	2,26	17,93	0,47	0,55	neutral	0,22	neutral	0,13	neutral	0,3	neutral	0,06	9	neutral	0,96	neutral	0,37	neutral	-2	deleterious	0,59	low_impact	-2,01	medium_impact	0,41	low_impact	-1,42	0,66	0,8	31,72	62,66	N	0,23	N	0,42	polymorphism	1	0,01	rs201246560	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8255	8255	G	A	MI.6622	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	670	224	V	M	Gta/Ata	-10,75	0	0	probably_damaging	1	neutral	0,23	neutral	2,45	neutral	-2,16	neutral	0,06	neutral_impact	-0,85	neutral	0,88	neutral	0,81	deleterious	2,88	21,8	0,41	0,5	disease	0,53	neutral	0,19	neutral	0,34	neutral	0,12	8	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,64	low_impact	-3,52	medium_impact	-0,09	low_impact	-1,9	0,62	0,8	31,72	62,66	N	0,48	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8256	8256	T	C	MI.6623	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	671	224	V	A	gTa/gCa	-2,65	0	0	probably_damaging	0,98	neutral	0,62	neutral	2,55	neutral	-0,53	neutral	0,85	neutral_impact	0,34	neutral	0,89	neutral	0,86	deleterious	2,23	17,69	0,47	0,55	neutral	0,38	neutral	0,17	neutral	0,37	neutral	0,12	8	neutral	0,97	neutral	0,32	neutral	-2	deleterious	0,62	low_impact	-2,3	medium_impact	0,32	medium_impact	-0,79	0,55	0,8	31,72	62,66	N	0,31	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8256	8256	T	G	MI.6624	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	671	224	V	G	gTa/gGa	-2,65	0	0	probably_damaging	0,99	neutral	0,39	neutral	2,46	neutral	-1,48	neutral	-0,27	neutral_impact	0,7	neutral	0,77	neutral	0,83	deleterious	4,12	23,8	0,3	0,45	disease	0,5	neutral	0,32	neutral	0,44	neutral	0,16	7	deleterious	0,99	neutral	0,2	neutral	-2	deleterious	0,66	low_impact	-2,58	medium_impact	0,1	medium_impact	-0,45	0,63	0,8	31,72	62,66	N	0,36	N	0,42	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8256	8256	T	A	MI.6625	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	671	224	V	E	gTa/gAa	-2,65	0	0	probably_damaging	0,99	neutral	0,42	neutral	2,47	neutral	-1,5	neutral	0,12	neutral_impact	0,7	neutral	0,8	neutral	0,83	deleterious	3,85	23,4	0,26	0,45	neutral	0,26	neutral	0,48	neutral	0,49	neutral	0,32	4	deleterious	0,99	neutral	0,22	neutral	-2	deleterious	0,65	low_impact	-2,58	medium_impact	0,13	medium_impact	-0,45	0,66	0,8	31,72	62,66	N	0,3	N	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8258	8258	T	A	MI.6626	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	673	225	F	I	Ttt/Att	-5,42	0	0	benign	0,05	neutral	0,42	neutral	2,59	neutral	-0,01	neutral	0,35	neutral_impact	0,77	neutral	0,8	neutral	0,8	neutral	1,44	13,02	0,51	0,6	neutral	0,28	neutral	0,36	neutral	0,34	neutral	0,14	7	neutral	0,54	deleterious	0,69	neutral	-6	neutral	0,17	medium_impact	0,47	medium_impact	0,13	medium_impact	-0,38	0,59	0,8	35,24	88,5	N	0,34	N	0,27	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8258	8258	T	G	MI.6627	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	673	225	F	V	Ttt/Gtt	-5,42	0	0	benign	0,08	neutral	0,52	neutral	2,6	neutral	0,15	neutral	0,29	low_impact	1,32	neutral	0,8	neutral	0,81	neutral	1,21	11,82	0,46	0,55	neutral	0,37	neutral	0,46	neutral	0,36	neutral	0,19	6	neutral	0,41	deleterious	0,72	neutral	-6	neutral	0,19	medium_impact	0,27	medium_impact	0,22	medium_impact	0,13	0,68	0,85	35,24	88,5	N	0,3	N	0,37	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8258	8258	T	C	MI.6628	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	673	225	F	L	Ttt/Ctt	-5,42	0	0	benign	0	neutral	0,71	neutral	2,67	neutral	0,62	neutral	1,04	neutral_impact	0,17	neutral	0,89	neutral	0,82	neutral	-0,4	0,39	0,54	0,6	neutral	0,31	neutral	0,06	neutral	0,13	neutral	0,06	9	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,07	high_impact	2,08	medium_impact	0,42	medium_impact	-0,95	0,64	0,8	35,24	88,5	N	0,47	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8259	8259	T	A	MI.6629	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	674	225	F	Y	tTt/tAt	-0,33	0	0	benign	0,2	neutral	1	neutral	2,54	neutral	-0,86	neutral	-0,19	low_impact	1,32	neutral	0,82	neutral	0,88	deleterious	2,81	21,4	0,56	0,6	disease	0,52	neutral	0,33	neutral	0,35	neutral	0,16	7	neutral	0,2	deleterious	0,9	neutral	-6	neutral	0,4	medium_impact	-0,16	high_impact	1,86	medium_impact	0,13	0,6	0,8	35,24	88,5	N	0,26	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8839	8839	G	T	MI.663	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	313	105	A	S	Gcc/Tcc	-2,19	0	0,01	probably_damaging	0,99	neutral	0,31	neutral	3,27	neutral	-1,92	deleterious	-2,63	low_impact	1,7	damaging	0,52	neutral	0,48	deleterious	3,64	23,2	0,27	0,65	neutral	0,42	disease	0,73	disease	0,54	neutral	0,44	1	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,78	low_impact	-2,65	medium_impact	0,1	medium_impact	0,36	0,71	0,9	49,12	8,67	N	0,37	N	0,95	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8259	8259	T	C	MI.6630	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	674	225	F	S	tTt/tCt	-0,33	0	0	benign	0,41	neutral	0,45	neutral	2,54	neutral	-0,64	neutral	1,4	low_impact	1,32	neutral	0,84	neutral	0,9	deleterious	2,93	22	0,5	0,6	neutral	0,33	neutral	0,43	neutral	0,28	neutral	0,19	6	neutral	0,49	deleterious	0,52	neutral	-6	neutral	0,41	medium_impact	-0,57	medium_impact	0,16	medium_impact	0,13	0,45	0,8	35,24	88,5	N	0,35	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8259	8259	T	G	MI.6631	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	674	225	F	C	tTt/tGt	-0,33	0	0	possibly_damaging	0,77	neutral	0,19	neutral	2,48	neutral	-2,64	neutral	-0,51	low_impact	1,32	neutral	0,71	neutral	0,74	deleterious	4,2	23,9	0,42	0,55	disease	0,71	neutral	0,48	neutral	0,46	neutral	0,38	2	neutral	0,87	neutral	0,21	neutral	-3	deleterious	0,61	low_impact	-1,21	medium_impact	-0,14	medium_impact	0,13	0,5	0,8	35,24	88,5	N	0,42	N	0,48	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8260	8260	T	A	MI.6632	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	675	225	F	L	ttT/ttA	-0,1	0	0	benign	0	neutral	0,71	neutral	2,67	neutral	0,62	neutral	1,04	neutral_impact	0,17	neutral	0,89	neutral	0,82	deleterious	0,03	2,91	0,54	0,6	neutral	0,31	neutral	0,06	neutral	0,13	neutral	0,06	9	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,07	high_impact	2,08	medium_impact	0,42	medium_impact	-0,95	0,64	0,8	35,24	88,5	N	0,48	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8260	8260	T	G	MI.6633	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	675	225	F	L	ttT/ttG	-0,1	0	0	benign	0	neutral	0,71	neutral	2,67	neutral	0,62	neutral	1,04	neutral_impact	0,17	neutral	0,89	neutral	0,82	neutral	-0,08	1,86	0,54	0,6	neutral	0,31	neutral	0,06	neutral	0,13	neutral	0,06	9	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,07	high_impact	2,08	medium_impact	0,42	medium_impact	-0,95	0,64	0,8	35,24	88,5	N	0,48	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8261	8261	A	C	MI.6634	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	676	226	T	P	Acc/Ccc	-2,88	0	0	benign	0,3	neutral	0,22	neutral	2,51	neutral	-1,74	neutral	-1,18	neutral_impact	0	neutral	0,7	neutral	0,74	deleterious	1,99	16,16	0,43	0,55	disease	0,8	neutral	0,38	disease	0,57	neutral	0,25	5	neutral	0,74	neutral	0,46	neutral	-6	neutral	0,43	medium_impact	-0,38	medium_impact	-0,1	low_impact	-1,11	0,68	0,85	NA	NA	N	0,37	N	0,58	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8261	8261	A	T	MI.6635	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	676	226	T	S	Acc/Tcc	-2,88	0	0	benign	0,07	neutral	0,42	neutral	2,59	neutral	-0,17	neutral	-0,31	neutral_impact	-0,8	neutral	0,8	neutral	0,87	deleterious	0,47	7,21	0,76	0,8	disease	0,59	neutral	0,08	neutral	0,39	neutral	0,04	9	neutral	0,53	deleterious	0,68	neutral	-6	neutral	0,17	medium_impact	0,33	medium_impact	0,13	low_impact	-1,86	0,81	0,85	NA	NA	N	0,38	N	0,19	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8261	8261	A	G	MI.6636	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	676	226	T	A	Acc/Gcc	-2,88	0	0	benign	0	neutral	0,52	neutral	2,63	neutral	0,15	neutral	-0,19	neutral_impact	-0,34	neutral	0,9	neutral	0,92	deleterious	0,52	7,57	0,74	0,8	neutral	0,4	neutral	0,14	neutral	0,39	neutral	0,11	8	neutral	0,47	deleterious	0,76	neutral	-6	neutral	0,11	high_impact	2,08	medium_impact	0,22	low_impact	-1,42	0,65	0,8	NA	NA	N	0,4	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8262	8262	C	G	MI.6637	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	677	226	T	S	aCc/aGc	2,9	0,89	0	benign	0,07	neutral	0,42	neutral	2,59	neutral	-0,17	neutral	-0,31	neutral_impact	-0,8	neutral	0,8	neutral	0,87	deleterious	0,71	8,87	0,76	0,8	disease	0,59	neutral	0,08	neutral	0,39	neutral	0,04	9	neutral	0,53	deleterious	0,68	neutral	-6	neutral	0,17	medium_impact	0,33	medium_impact	0,13	low_impact	-1,86	0,81	0,85	NA	NA	N	0,38	N	0,19	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8262	8262	C	T	MI.6638	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	677	226	T	I	aCc/aTc	2,9	0,89	0	benign	0,18	neutral	0,39	neutral	2,58	neutral	-0,38	neutral	1,15	neutral_impact	0	neutral	0,86	neutral	0,86	deleterious	0,69	8,75	0,71	0,75	disease	0,63	neutral	0,31	neutral	0,28	neutral	0,22	6	neutral	0,53	deleterious	0,61	neutral	-6	neutral	0,25	medium_impact	-0,11	medium_impact	0,1	low_impact	-1,11	0,67	0,85	NA	NA	N	0,33	N	0,18	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8262	8262	C	A	MI.6639	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	677	226	T	N	aCc/aAc	2,9	0,89	0	benign	0,3	neutral	0,32	neutral	2,54	neutral	-1,11	neutral	-1	neutral_impact	-0,98	neutral	0,78	neutral	0,83	deleterious	2,08	16,7	0,67	0,7	disease	0,54	neutral	0,3	neutral	0,45	neutral	0,19	6	neutral	0,61	deleterious	0,51	neutral	-6	neutral	0,31	medium_impact	-0,38	medium_impact	0,02	low_impact	-2,02	0,74	0,85	NA	NA	N	0,34	N	0,45	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8839	8839	G	C	MI.664	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	313	105	A	P	Gcc/Ccc	-2,19	0	0,01	probably_damaging	1	deleterious	0	neutral	2,97	deleterious	-6,3	deleterious	-4,63	high_impact	3,97	damaging	0,41	neutral	0,4	deleterious	3,76	23,3	0,13	0,65	disease	0,95	disease	0,9	disease	0,76	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	high_impact	2,3	0,58	0,9	49,12	8,67	P	0,57	P	0,97	disease_causing_automatic	1	0,35	rs369202065	Pathogenic	Leigh_syndrome	RCV000144024.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	8264	8264	C	G	MI.6640	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	679	227	L	V	Cta/Gta	-0,8	0	0	probably_damaging	0,98	neutral	0,62	neutral	2,52	neutral	-0,72	neutral	-1,19	neutral_impact	0	neutral	0,7	neutral	0,52	deleterious	3,58	23,2	0,46	0,55	NA	NA	neutral	0,17	neutral	0,38	neutral	0,23	5	neutral	0,97	neutral	0,32	neutral	-2	deleterious	0,87	low_impact	-2,3	medium_impact	0,32	low_impact	-1,11	0,84	0,9	NA	NA	N	0,26	N	0,12	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8264	8264	C	A	MI.6641	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	679	227	L	M	Cta/Ata	-0,8	0	0	probably_damaging	1	neutral	0,26	neutral	2,43	neutral	-2,4	neutral	-0,63	neutral_impact	0	neutral	0,74	neutral	0,52	deleterious	2,7	20,8	0,31	0,45	NA	NA	neutral	0,13	neutral	0,33	neutral	0,18	6	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,88	low_impact	-3,52	medium_impact	-0,05	low_impact	-1,11	0,63	0,8	NA	NA	N	0,42	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8265	8265	T	G	MI.6642	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	680	227	L	R	cTa/cGa	-3,11	0	0	probably_damaging	1	neutral	0,34	neutral	2,46	neutral	-1,8	deleterious	-2,62	neutral_impact	0	damaging	0,6	neutral	0,46	deleterious	4,36	24,1	0,31	0,45	NA	NA	neutral	0,48	disease	0,62	neutral	0,34	3	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,9	low_impact	-3,52	medium_impact	0,05	low_impact	-1,11	0,58	0,8	NA	NA	N	0,27	N	0,51	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8265	8265	T	C	MI.6643	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	680	227	L	P	cTa/cCa	-3,11	0	0	probably_damaging	1	neutral	0,2	neutral	2,43	neutral	-2,71	deleterious	-2,54	neutral_impact	0	damaging	0,56	neutral	0,42	deleterious	4,07	23,7	0,34	0,5	NA	NA	neutral	0,31	disease	0,53	neutral	0,21	6	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,9	low_impact	-3,52	medium_impact	-0,13	low_impact	-1,11	0,45	0,8	NA	NA	N	0,35	N	0,74	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8265	8265	T	A	MI.6644	MT-CO2	IV	ENSG00000198712	ENSP00000354876	ENST00000361739	COX2_HUMAN	P00403	4513	YP_003024029.1	680	227	L	Q	cTa/cAa	-3,11	0	0	probably_damaging	1	neutral	0,33	neutral	2,44	neutral	-2,21	neutral	-2,05	neutral_impact	0	neutral	0,68	neutral	0,52	deleterious	4,23	23,9	0,32	0,5	NA	NA	neutral	0,31	disease	0,56	neutral	0,21	6	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,89	low_impact	-3,52	medium_impact	0,04	low_impact	-1,11	0,65	0,8	NA	NA	N	0,3	N	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9207	9207	A	C	MI.6645	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	1	1	M	L	Atg/Ctg	6,61	1	0	benign	0,42	deleterious	0	neutral	2,58	neutral	1,29	neutral	-1,85	NA	NA	damaging	0,53	damaging	0,1	deleterious	3,11	22,5	0,07	0,35	NA	NA	neutral	0,15	neutral	0,35	neutral	0,21	6	deleterious	1	neutral	0,29	NA	0	neutral	0,36	NA	NA	NA	NA	NA	NA	0,34	0,8	74,33	11,77	P	0,6	P	0,94	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9207	9207	A	T	MI.6646	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	1	1	M	L	Atg/Ttg	6,61	1	0	benign	0,42	deleterious	0	neutral	2,58	neutral	1,29	neutral	-1,85	NA	NA	damaging	0,53	damaging	0,1	deleterious	3,09	22,5	0,07	0,35	NA	NA	neutral	0,15	neutral	0,35	neutral	0,21	6	deleterious	1	neutral	0,29	NA	0	neutral	0,36	NA	NA	NA	NA	NA	NA	0,34	0,8	74,33	11,77	P	0,61	P	0,94	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9207	9207	A	G	MI.6647	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	1	1	M	V	Atg/Gtg	6,61	1	0	possibly_damaging	0,54	deleterious	0	neutral	2,55	neutral	0,83	neutral	-2,46	NA	NA	neutral	0,61	damaging	0,09	deleterious	2,52	19,61	0,08	0,35	NA	NA	neutral	0,26	disease	0,62	neutral	0,33	3	deleterious	1	neutral	0,23	deleterious	3	neutral	0,42	NA	NA	NA	NA	NA	NA	0,22	0,8	74,33	11,77	P	0,51	P	0,95	NA	NA	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9208	9208	T	C	MI.6648	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	2	1	M	T	aTg/aCg	8,69	1	0	possibly_damaging	0,73	deleterious	0	NA	NA	neutral	-0,27	NA	NA	NA	NA	neutral	0,63	damaging	0,09	deleterious	2,7	20,8	0,09	0,35	NA	NA	neutral	0,38	disease	0,53	neutral	0,29	4	deleterious	1	neutral	0,14	deleterious	3	deleterious	0,67	NA	NA	NA	NA	NA	NA	0,09	0,8	74,33	11,77	P	0,49	N	0,99	NA	NA	0,06	.	.	.	.	.	.	COSM1133874	.	.	.	.	.	.	.	.
chrM	9208	9208	T	A	MI.6649	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	2	1	M	K	aTg/aAg	8,69	1	0	possibly_damaging	0,73	deleterious	0	NA	NA	neutral	-0,19	NA	NA	NA	NA	neutral	0,64	damaging	0,13	deleterious	3,86	23,5	0,08	0,35	NA	NA	neutral	0,36	disease	0,65	neutral	0,33	4	deleterious	1	neutral	0,14	deleterious	3	deleterious	0,66	NA	NA	NA	NA	NA	NA	0,13	0,8	74,33	11,77	P	0,6	P	0,99	NA	NA	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8839	8839	G	A	MI.665	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	313	105	A	T	Gcc/Acc	-2,19	0	0,01	probably_damaging	1	neutral	0,09	neutral	2,99	deleterious	-4,96	deleterious	-3,64	high_impact	3,62	damaging	0,58	neutral	0,5	deleterious	4,19	23,8	0,31	0,65	disease	0,88	disease	0,84	disease	0,65	disease	0,73	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,87	low_impact	-3,6	medium_impact	-0,28	high_impact	2,01	0,76	0,9	49,12	8,67	N	0,31	N	0,8	disease_causing_automatic	1	0,22	rs369202065	Pathogenic	Leigh_syndrome	RCV000144024.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	9209	9209	G	C	MI.6650	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	3	1	M	I	atG/atC	7,53	1	0	possibly_damaging	0,63	deleterious	0	NA	NA	neutral	0,69	NA	NA	NA	NA	damaging	0,55	damaging	0,11	deleterious	3,29	22,8	0,08	0,35	NA	NA	neutral	0,28	neutral	0,48	neutral	0,19	6	deleterious	1	neutral	0,19	deleterious	3	deleterious	0,54	NA	NA	NA	NA	NA	NA	0,48	0,8	74,33	11,77	P	0,58	P	0,94	NA	NA	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9210	9210	A	G	MI.6651	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	4	2	T	A	Acc/Gcc	7,53	1	0	benign	0	neutral	1	neutral	2,6	neutral	-0,1	neutral	-1,44	neutral_impact	-0,12	neutral	0,69	neutral	0,93	neutral	-0,83	0,04	0,27	0,45	NA	NA	neutral	0,02	neutral	0,18	neutral	0,24	5	neutral	0	deleterious	1	neutral	-6	neutral	0,03	high_impact	2,05	high_impact	1,9	low_impact	-1,29	0,31	0,8	75,1	10,48	P	0,53	P	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9210	9210	A	C	MI.6652	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	4	2	T	P	Acc/Ccc	7,53	1	0	benign	0,01	neutral	0,19	neutral	2,53	neutral	-2,25	deleterious	-2,73	low_impact	1,75	damaging	0,56	neutral	0,42	neutral	1,27	12,09	0,14	0,4	NA	NA	neutral	0,29	neutral	0,18	neutral	0,22	6	neutral	0,81	deleterious	0,59	neutral	-6	neutral	0,09	medium_impact	1,07	medium_impact	-0,17	medium_impact	0,39	0,44	0,8	75,1	10,48	P	0,61	P	0,9	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9210	9210	A	T	MI.6653	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	4	2	T	S	Acc/Tcc	7,53	1	0	benign	0	neutral	0,77	neutral	2,57	neutral	-0,26	neutral	-1,06	neutral_impact	0,72	neutral	0,69	neutral	0,87	neutral	-0,19	1,13	0,42	0,55	NA	NA	neutral	0,05	neutral	0,06	neutral	0,22	6	neutral	0,23	deleterious	0,89	neutral	-6	neutral	0,04	high_impact	2,05	medium_impact	0,49	medium_impact	-0,54	0,53	0,8	75,1	10,48	P	0,57	P	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9211	9211	C	G	MI.6654	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	5	2	T	S	aCc/aGc	1,75	1	0	benign	0	neutral	0,77	neutral	2,57	neutral	-0,26	neutral	-1,06	neutral_impact	0,72	neutral	0,69	neutral	0,87	deleterious	0	2,55	0,42	0,55	NA	NA	neutral	0,05	neutral	0,06	neutral	0,22	6	neutral	0,23	deleterious	0,89	neutral	-6	neutral	0,04	high_impact	2,05	medium_impact	0,49	medium_impact	-0,54	0,53	0,8	75,1	10,48	N	0,47	N	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9211	9211	C	A	MI.6655	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	5	2	T	N	aCc/aAc	1,75	1	0	benign	0,01	neutral	0,39	neutral	2,55	neutral	-1,35	neutral	-1,86	neutral_impact	0,65	neutral	0,69	neutral	0,83	deleterious	0,37	6,37	0,41	0,5	NA	NA	neutral	0,14	neutral	0,08	neutral	0,26	5	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,05	medium_impact	1,07	medium_impact	0,08	medium_impact	-0,6	0,44	0,8	75,1	10,48	P	0,53	P	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9211	9211	C	T	MI.6656	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	5	2	T	I	aCc/aTc	1,75	1	0	benign	0	neutral	0,22	neutral	2,57	neutral	-1,47	neutral	-2,45	low_impact	1,12	neutral	0,68	neutral	0,9	deleterious	1,84	15,2	0,23	0,45	NA	NA	neutral	0,22	neutral	0,11	neutral	0,21	6	neutral	0,78	deleterious	0,61	neutral	-6	neutral	0,06	high_impact	2,05	medium_impact	-0,12	medium_impact	-0,18	0,36	0,8	75,1	10,48	P	0,56	P	0,61	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9213	9213	C	T	MI.6657	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	7	3	H	Y	Cac/Tac	-1,49	0	0	possibly_damaging	0,65	neutral	1	neutral	2,59	neutral	-1,28	neutral	-2,48	medium_impact	1,99	neutral	0,63	neutral	0,31	deleterious	3,55	23,1	0,2	0,45	NA	NA	neutral	0,45	neutral	0,36	neutral	0,24	5	neutral	0,65	deleterious	0,68	NA	0	deleterious	0,56	low_impact	-1,13	high_impact	1,9	medium_impact	0,6	0,3	0,8	74,33	12,75	N	0,23	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9213	9213	C	G	MI.6658	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	7	3	H	D	Cac/Gac	-1,49	0	0	possibly_damaging	0,81	neutral	0,19	neutral	2,56	neutral	-0,25	deleterious	-3,59	medium_impact	2,48	neutral	0,63	neutral	0,36	deleterious	3,7	23,3	0,2	0,45	NA	NA	disease	0,5	disease	0,53	disease	0,56	1	neutral	0,89	neutral	0,19	NA	0	deleterious	0,59	low_impact	-1,48	medium_impact	-0,17	medium_impact	1,04	0,19	0,8	74,33	12,75	N	0,35	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9213	9213	C	A	MI.6659	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	7	3	H	N	Cac/Aac	-1,49	0	0	possibly_damaging	0,73	neutral	0,34	neutral	2,58	neutral	-0,23	neutral	-2,15	low_impact	1,68	neutral	0,67	neutral	0,72	deleterious	2,67	20,6	0,37	0,5	NA	NA	neutral	0,27	neutral	0,39	neutral	0,17	7	neutral	0,77	neutral	0,31	neutral	-3	deleterious	0,49	low_impact	-1,29	medium_impact	0,03	medium_impact	0,32	0,26	0,8	74,33	12,75	N	0,42	N	0,96	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8840	8840	C	T	MI.666	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	314	105	A	V	gCc/gTc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	3,02	deleterious	-4,33	deleterious	-3,75	high_impact	3,97	damaging	0,44	neutral	0,34	deleterious	4,46	24,2	0,33	0,65	disease	0,94	disease	0,85	disease	0,64	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,3	0,62	0,9	49,12	8,67	P	0,69	P	0,75	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9214	9214	A	G	MI.6660	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	8	3	H	R	cAc/cGc	7,3	1	0	possibly_damaging	0,66	neutral	0,46	neutral	2,61	neutral	-0,12	neutral	-2,41	low_impact	1,71	neutral	0,88	neutral	0,7	deleterious	3,31	22,9	0,22	0,45	NA	NA	neutral	0,41	neutral	0,38	neutral	0,18	6	neutral	0,65	neutral	0,4	neutral	-3	deleterious	0,55	low_impact	-1,15	medium_impact	0,15	medium_impact	0,35	0,23	0,8	74,33	12,75	P	0,55	P	0,99	polymorphism	1	0,06	.	.	.	.	.	.	COSM1155698	.	.	.	.	.	.	.	.
chrM	9214	9214	A	C	MI.6661	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	8	3	H	P	cAc/cCc	7,3	1	0	possibly_damaging	0,88	neutral	0,19	neutral	2,56	neutral	-1,52	deleterious	-4,11	medium_impact	2,68	neutral	0,62	neutral	0,35	deleterious	3,59	23,2	0,17	0,45	NA	NA	disease	0,59	neutral	0,49	disease	0,52	0	neutral	0,93	neutral	0,16	NA	0	deleterious	0,72	low_impact	-1,71	medium_impact	-0,17	medium_impact	1,22	0,19	0,8	74,33	12,75	P	0,57	P	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9214	9214	A	T	MI.6662	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	8	3	H	L	cAc/cTc	7,3	1	0	possibly_damaging	0,66	neutral	0,73	neutral	2,68	neutral	0	deleterious	-4,22	medium_impact	2,13	neutral	0,65	neutral	0,45	deleterious	4,19	23,8	0,2	0,45	NA	NA	neutral	0,47	neutral	0,47	neutral	0,31	4	neutral	0,59	deleterious	0,54	NA	0	deleterious	0,56	low_impact	-1,15	medium_impact	0,44	medium_impact	0,73	0,17	0,8	74,33	12,75	P	0,53	P	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9215	9215	C	A	MI.6663	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	9	3	H	Q	caC/caA	8,69	1	0	possibly_damaging	0,77	neutral	0,37	neutral	2,57	neutral	-0,05	neutral	-2,33	low_impact	1,49	neutral	0,65	neutral	0,57	deleterious	3,7	23,3	0,24	0,45	NA	NA	neutral	0,32	neutral	0,39	neutral	0,17	7	neutral	0,79	neutral	0,3	neutral	-3	deleterious	0,56	low_impact	-1,38	medium_impact	0,06	medium_impact	0,15	0,34	0,8	74,33	12,75	P	0,59	P	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9215	9215	C	G	MI.6664	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	9	3	H	Q	caC/caG	8,69	1	0	possibly_damaging	0,77	neutral	0,37	neutral	2,57	neutral	-0,05	neutral	-2,33	low_impact	1,49	neutral	0,65	neutral	0,57	deleterious	3,36	22,9	0,24	0,45	NA	NA	neutral	0,32	neutral	0,39	neutral	0,17	7	neutral	0,79	neutral	0,3	neutral	-3	deleterious	0,56	low_impact	-1,38	medium_impact	0,06	medium_impact	0,15	0,34	0,8	74,33	12,75	P	0,58	P	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9216	9216	C	G	MI.6665	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	10	4	Q	E	Caa/Gaa	2,21	1	0	possibly_damaging	0,58	neutral	0,19	neutral	2,58	neutral	-0,29	neutral	-1,6	medium_impact	2,98	neutral	0,62	neutral	0,35	deleterious	2,86	21,7	0,38	0,5	NA	NA	neutral	0,27	disease	0,54	neutral	0,37	3	neutral	0,81	neutral	0,31	NA	0	deleterious	0,51	low_impact	-1,01	medium_impact	-0,17	medium_impact	1,49	0,51	0,8	74,71	11,99	P	0,53	P	0,93	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9216	9216	C	A	MI.6666	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	10	4	Q	K	Caa/Aaa	2,21	1	0	possibly_damaging	0,77	neutral	0,29	neutral	2,61	neutral	0,58	neutral	-1,99	low_impact	1,48	neutral	0,62	neutral	0,57	deleterious	2,82	21,5	0,41	0,5	NA	NA	neutral	0,18	neutral	0,25	neutral	0,22	6	neutral	0,82	neutral	0,26	neutral	-3	deleterious	0,53	low_impact	-1,38	medium_impact	-0,03	medium_impact	0,14	0,49	0,8	74,71	11,99	P	0,58	P	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9217	9217	A	C	MI.6667	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	11	4	Q	P	cAa/cCa	3,6	1	0	probably_damaging	0,92	neutral	0,25	neutral	2,53	neutral	-2,41	deleterious	-3,4	medium_impact	2,77	damaging	0,6	neutral	0,3	deleterious	3,24	22,8	0,14	0,4	NA	NA	disease	0,54	disease	0,51	disease	0,55	1	neutral	0,94	neutral	0,17	deleterious	1	deleterious	0,71	low_impact	-1,9	medium_impact	-0,08	medium_impact	1,3	0,28	0,8	74,71	11,99	N	0,46	N	0,98	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9217	9217	A	T	MI.6668	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	11	4	Q	L	cAa/cTa	3,6	1	0	possibly_damaging	0,77	neutral	0,72	neutral	2,52	neutral	-1,73	deleterious	-3,98	medium_impact	2,35	neutral	0,64	neutral	0,4	deleterious	3,67	23,3	0,19	0,45	NA	NA	neutral	0,39	neutral	0,43	neutral	0,19	6	neutral	0,72	deleterious	0,48	NA	0	deleterious	0,61	low_impact	-1,38	medium_impact	0,43	medium_impact	0,92	0,26	0,8	74,71	11,99	N	0,45	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9217	9217	A	G	MI.6669	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	11	4	Q	R	cAa/cGa	3,6	1	0	possibly_damaging	0,84	neutral	0,23	neutral	2,53	neutral	-0,64	neutral	-2,05	low_impact	1,9	neutral	0,65	neutral	0,46	deleterious	3,33	22,9	0,34	0,5	NA	NA	neutral	0,38	neutral	0,35	neutral	0,19	6	neutral	0,89	neutral	0,2	neutral	-3	deleterious	0,63	low_impact	-1,57	medium_impact	-0,11	medium_impact	0,52	0,32	0,8	74,71	11,99	P	0,58	P	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8840	8840	C	A	MI.667	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	314	105	A	D	gCc/gAc	6,14	1	0	probably_damaging	1	deleterious	0	neutral	2,96	deleterious	-7,05	deleterious	-5,5	high_impact	4,32	damaging	0,56	neutral	0,42	deleterious	4,43	24,2	0,1	0,65	disease	0,96	disease	0,92	disease	0,74	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,6	low_impact	-1,4	high_impact	2,6	0,55	0,9	49,12	8,67	P	0,51	P	0,99	disease_causing	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9218	9218	A	C	MI.6670	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	12	4	Q	H	caA/caC	5,68	1	0	probably_damaging	0,95	neutral	0,81	neutral	2,5	neutral	-2,17	neutral	-2,18	medium_impact	2,17	neutral	0,62	neutral	0,58	deleterious	3,36	22,9	0,3	0,45	NA	NA	neutral	0,25	neutral	0,25	neutral	0,21	6	neutral	0,95	neutral	0,43	deleterious	1	deleterious	0,68	low_impact	-2,11	medium_impact	0,55	medium_impact	0,76	0,3	0,8	74,71	11,99	N	0,48	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9218	9218	A	T	MI.6671	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	12	4	Q	H	caA/caT	5,68	1	0	probably_damaging	0,95	neutral	0,81	neutral	2,5	neutral	-2,17	neutral	-2,18	medium_impact	2,17	neutral	0,62	neutral	0,58	deleterious	3,52	23,1	0,3	0,45	NA	NA	neutral	0,25	neutral	0,25	neutral	0,21	6	neutral	0,95	neutral	0,43	deleterious	1	deleterious	0,68	low_impact	-2,11	medium_impact	0,55	medium_impact	0,76	0,3	0,8	74,71	11,99	P	0,51	P	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9219	9219	T	C	MI.6672	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	13	5	S	P	Tca/Cca	3,37	1	0	benign	0,07	neutral	0,23	neutral	2,55	neutral	-1,64	neutral	-1,14	neutral_impact	0,55	damaging	0,56	neutral	0,29	neutral	0,97	10,47	0,3	0,45	NA	NA	neutral	0,36	neutral	0,32	neutral	0,15	7	neutral	0,75	deleterious	0,58	neutral	-6	neutral	0,13	medium_impact	0,22	medium_impact	-0,11	medium_impact	-0,69	0,19	0,8	23,75	21,19	P	0,55	P	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9219	9219	T	G	MI.6673	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	13	5	S	A	Tca/Gca	3,37	1	0	benign	0	neutral	0,53	neutral	2,58	neutral	-0,08	neutral	-0,85	neutral_impact	-1,08	neutral	0,68	neutral	0,86	neutral	-1,04	0,01	0,5	0,6	NA	NA	neutral	0,03	neutral	0,29	neutral	0,17	7	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,04	high_impact	2,05	medium_impact	0,22	low_impact	-2,15	0,34	0,8	23,75	21,19	N	0,49	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9219	9219	T	A	MI.6674	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	13	5	S	T	Tca/Aca	3,37	1	0	benign	0	neutral	0,41	neutral	2,57	neutral	-0,39	neutral	0,17	neutral_impact	-0,85	neutral	0,77	neutral	0,97	neutral	-0,37	0,47	0,47	0,55	NA	NA	neutral	0,06	neutral	0,15	neutral	0,19	6	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,05	high_impact	2,05	medium_impact	0,1	low_impact	-1,94	0,48	0,8	23,75	21,19	P	0,55	P	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9220	9220	C	G	MI.6675	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	14	5	S	W	tCa/tGa	1,29	0,98	0	benign	0,32	neutral	0,18	neutral	2,5	deleterious	-4,38	neutral	-2,47	low_impact	0,9	neutral	0,63	neutral	0,38	deleterious	2,78	21,2	0,16	0,45	NA	NA	neutral	0,34	neutral	0,46	neutral	0,16	7	neutral	0,79	neutral	0,43	neutral	-6	neutral	0,42	medium_impact	-0,55	medium_impact	-0,18	medium_impact	-0,38	0,1	0,8	23,75	21,19	N	0,5	N	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9220	9220	C	T	MI.6676	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	14	5	S	L	tCa/tTa	1,29	0,98	0	benign	0	neutral	0,66	neutral	2,6	neutral	-0,96	neutral	-1,54	neutral_impact	-0,3	neutral	0,75	neutral	0,78	neutral	0,93	10,25	0,36	0,5	NA	NA	neutral	0,15	neutral	0,33	neutral	0,2	6	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,06	high_impact	2,05	medium_impact	0,36	low_impact	-1,45	0,5	0,8	23,75	21,19	N	0,42	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9222	9222	C	G	MI.6677	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	16	6	H	D	Cat/Gat	-5,19	0	0	probably_damaging	1	neutral	0,18	neutral	2,17	neutral	-1,08	deleterious	-6,46	medium_impact	2,87	neutral	0,6	damaging	0,03	deleterious	3,88	23,5	0,17	0,45	NA	NA	disease	0,58	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	-0,18	medium_impact	1,39	0,28	0,8	73,56	11,82	N	0,3	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9222	9222	C	T	MI.6678	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	16	6	H	Y	Cat/Tat	-5,19	0	0	probably_damaging	0,99	neutral	0,92	neutral	2,19	neutral	-2,87	deleterious	-4,48	medium_impact	2,95	damaging	0,54	damaging	0,03	deleterious	3,77	23,4	0,23	0,45	NA	NA	disease	0,56	disease	0,73	disease	0,7	4	deleterious	0,99	neutral	0,47	deleterious	1	deleterious	0,78	low_impact	-2,81	medium_impact	0,8	medium_impact	1,46	0,21	0,8	73,56	11,82	N	0,21	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9222	9222	C	A	MI.6679	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	16	6	H	N	Cat/Aat	-5,19	0	0	probably_damaging	0,99	neutral	0,45	neutral	2,17	neutral	-1,2	deleterious	-4,66	low_impact	1,87	damaging	0,49	damaging	0,06	deleterious	4,02	23,6	0,43	0,55	NA	NA	neutral	0,45	disease	0,73	disease	0,53	1	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,76	low_impact	-2,81	medium_impact	0,14	medium_impact	0,49	0,25	0,8	73,56	11,82	N	0,28	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8840	8840	C	G	MI.668	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	314	105	A	G	gCc/gGc	6,14	1	0	probably_damaging	0,99	neutral	0,14	neutral	3,1	deleterious	-3,14	deleterious	-3,68	medium_impact	2,25	damaging	0,54	neutral	0,48	deleterious	3,89	23,5	0,22	0,65	disease	0,7	disease	0,74	neutral	0,48	neutral	0,43	1	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,8	low_impact	-2,65	medium_impact	-0,15	medium_impact	0,83	0,74	0,9	49,12	8,67	P	0,53	P	0,86	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9223	9223	A	C	MI.6680	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	17	6	H	P	cAt/cCt	4,52	1	0	probably_damaging	1	neutral	0,35	neutral	2,14	neutral	-2,34	deleterious	-6,38	medium_impact	2,64	damaging	0,59	damaging	0,04	deleterious	3,16	22,6	0,14	0,4	NA	NA	disease	0,6	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,82	low_impact	-3,78	medium_impact	0,04	medium_impact	1,18	0,18	0,8	73,56	11,82	N	0,4	N	0,98	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9223	9223	A	T	MI.6681	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	17	6	H	L	cAt/cTt	4,52	1	0	probably_damaging	1	neutral	0,61	neutral	2,22	neutral	-1,68	deleterious	-7,99	medium_impact	3,15	damaging	0,57	damaging	0,04	deleterious	3,68	23,3	0,18	0,45	NA	NA	disease	0,57	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,78	low_impact	-3,78	medium_impact	0,3	medium_impact	1,64	0,15	0,8	73,56	11,82	N	0,47	N	0,96	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9223	9223	A	G	MI.6682	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	17	6	H	R	cAt/cGt	4,52	1	0	probably_damaging	1	neutral	0,33	neutral	2,18	neutral	-1,24	deleterious	-5,74	medium_impact	3,15	neutral	0,66	damaging	0,06	deleterious	2,81	21,4	0,24	0,45	NA	NA	disease	0,55	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,8	low_impact	-3,78	medium_impact	0,02	medium_impact	1,64	0,2	0,8	73,56	11,82	N	0,47	N	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9224	9224	T	A	MI.6683	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	18	6	H	Q	caT/caA	8,69	1	0	probably_damaging	1	neutral	0,26	neutral	2,18	neutral	-0,96	deleterious	-5,45	low_impact	1,72	damaging	0,57	damaging	0,04	deleterious	3,78	23,4	0,33	0,5	NA	NA	neutral	0,49	disease	0,73	disease	0,54	1	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,78	low_impact	-3,78	medium_impact	-0,07	medium_impact	0,36	0,3	0,8	73,56	11,82	P	0,5	N	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9224	9224	T	G	MI.6684	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	18	6	H	Q	caT/caG	8,69	1	0	probably_damaging	1	neutral	0,26	neutral	2,18	neutral	-0,96	deleterious	-5,45	low_impact	1,72	damaging	0,57	damaging	0,04	deleterious	3,57	23,2	0,33	0,5	NA	NA	neutral	0,49	disease	0,73	disease	0,54	1	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,78	low_impact	-3,78	medium_impact	-0,07	medium_impact	0,36	0,3	0,8	73,56	11,82	P	0,49	N	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9225	9225	G	A	MI.6685	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	19	7	A	T	Gcc/Acc	-2,19	0	0	possibly_damaging	0,47	neutral	0,35	neutral	2,29	neutral	-0,47	neutral	-0,21	neutral_impact	0,38	neutral	0,7	neutral	0,56	deleterious	2,81	21,4	0,43	0,55	NA	NA	neutral	0,31	neutral	0,32	neutral	0,17	7	neutral	0,62	neutral	0,44	neutral	-3	deleterious	0,46	medium_impact	-0,82	medium_impact	0,04	medium_impact	-0,84	0,64	0,8	55,56	9,3	N	0,41	N	0,86	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9225	9225	G	T	MI.6686	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	19	7	A	S	Gcc/Tcc	-2,19	0	0	benign	0,34	neutral	0,38	neutral	2,37	neutral	0,52	neutral	-0,1	neutral_impact	-0,42	neutral	0,68	neutral	0,94	deleterious	2,01	16,3	0,52	0,6	NA	NA	neutral	0,21	neutral	0,18	neutral	0,19	6	neutral	0,55	deleterious	0,52	neutral	-6	neutral	0,29	medium_impact	-0,59	medium_impact	0,07	low_impact	-1,56	0,31	0,8	55,56	9,3	N	0,52	P	0,89	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9225	9225	G	C	MI.6687	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	19	7	A	P	Gcc/Ccc	-2,19	0	0	benign	0,03	neutral	0,26	neutral	2,43	neutral	1,01	neutral	4,49	neutral_impact	-2,04	neutral	0,64	neutral	0,35	neutral	-0,39	0,4	0,36	0,5	NA	NA	neutral	0,05	neutral	0,16	neutral	0,2	6	neutral	0,72	deleterious	0,62	neutral	-6	neutral	0,14	medium_impact	0,6	medium_impact	-0,07	low_impact	-3,01	0,37	0,8	55,56	9,3	N	0,48	N	0,99	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9226	9226	C	A	MI.6688	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	20	7	A	D	gCc/gAc	2,21	0,99	0	probably_damaging	0,96	neutral	0,17	neutral	2,29	neutral	-0,54	neutral	-0,62	neutral_impact	-0,32	neutral	0,62	damaging	0,02	deleterious	4,52	24,3	0,35	0,5	NA	NA	neutral	0,43	neutral	0,31	neutral	0,2	6	neutral	0,98	neutral	0,11	neutral	-2	deleterious	0,71	low_impact	-2,21	medium_impact	-0,2	low_impact	-1,47	0,22	0,8	55,56	9,3	N	0,43	N	0,99	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9226	9226	C	G	MI.6689	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	20	7	A	G	gCc/gGc	2,21	0,99	0	benign	0,21	neutral	0,29	neutral	2,26	neutral	-1,09	neutral	-1,16	neutral_impact	-0,26	neutral	0,72	neutral	0,29	deleterious	2,32	18,27	0,51	0,6	NA	NA	neutral	0,29	neutral	0,45	neutral	0,17	7	neutral	0,65	deleterious	0,54	neutral	-6	neutral	0,25	medium_impact	-0,31	medium_impact	-0,03	low_impact	-1,42	0,5	0,8	55,56	9,3	N	0,45	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8842	8842	A	C	MI.669	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	316	106	I	L	Atc/Ctc	-11,44	0	0,02	benign	0,06	neutral	1	neutral	4,54	neutral	0,8	neutral	-1,59	neutral_impact	-0,54	neutral	0,92	neutral	0,58	deleterious	0,69	8,77	0,35	0,65	neutral	0,29	neutral	0,3	neutral	0,26	neutral	0,45	1	neutral	0,06	deleterious	0,97	neutral	-6	neutral	0,14	medium_impact	0,38	high_impact	1,98	low_impact	-1,56	0,59	0,9	42,48	7,64	N	0,29	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9226	9226	C	T	MI.6690	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	20	7	A	V	gCc/gTc	2,21	0,99	0	possibly_damaging	0,5	neutral	0,42	neutral	2,26	neutral	-1,06	neutral	-1,15	low_impact	0,9	damaging	0,59	damaging	0,09	deleterious	4,27	24	0,42	0,5	NA	NA	neutral	0,38	disease	0,51	neutral	0,25	5	neutral	0,56	neutral	0,46	neutral	-3	deleterious	0,57	medium_impact	-0,87	medium_impact	0,11	medium_impact	-0,38	0,64	0,8	55,56	9,3	N	0,42	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9228	9228	T	G	MI.6691	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	22	8	Y	D	Tat/Gat	-5,42	0	0	probably_damaging	1	neutral	0,16	neutral	2	deleterious	-6,38	deleterious	-6,57	high_impact	3,64	damaging	0,6	damaging	0,05	deleterious	3,81	23,4	0,03	0,35	NA	NA	disease	0,65	disease	0,81	disease	0,75	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,77	low_impact	-3,78	medium_impact	-0,22	high_impact	2,08	0,1	0,8	78,16	10,8	N	0,31	N	0,99	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9228	9228	T	C	MI.6692	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	22	8	Y	H	Tat/Cat	-5,42	0	0	probably_damaging	1	neutral	0,64	neutral	2,02	deleterious	-4,74	deleterious	-3,47	medium_impact	2,84	neutral	0,64	damaging	0,07	deleterious	3,39	23	0,09	0,35	NA	NA	neutral	0,47	disease	0,81	disease	0,71	4	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	0,33	medium_impact	1,36	0,09	0,8	78,16	10,8	N	0,26	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9228	9228	T	A	MI.6693	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	22	8	Y	N	Tat/Aat	-5,42	0	0	probably_damaging	1	neutral	0,29	neutral	2,01	deleterious	-5,59	deleterious	-6,1	medium_impact	2,94	neutral	0,65	damaging	0,07	deleterious	3,86	23,5	0,05	0,35	NA	NA	disease	0,55	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	-0,03	medium_impact	1,45	0,1	0,8	78,16	10,8	N	0,27	N	1	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9229	9229	A	T	MI.6694	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	23	8	Y	F	tAt/tTt	5,91	1	0	probably_damaging	0,98	neutral	0,6	neutral	2,44	neutral	-2	neutral	-0,8	neutral_impact	-0,21	neutral	0,69	neutral	0,48	neutral	1,47	13,17	0,19	0,45	NA	NA	neutral	0,05	neutral	0,31	neutral	0,15	7	deleterious	0,98	neutral	0,31	neutral	-2	deleterious	0,71	low_impact	-2,51	medium_impact	0,29	low_impact	-1,37	0,2	0,8	78,16	10,8	P	0,57	P	0,72	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9229	9229	A	G	MI.6695	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	23	8	Y	C	tAt/tGt	5,91	1	0	probably_damaging	1	neutral	0,14	neutral	2	deleterious	-6,64	deleterious	-5,89	high_impact	3,64	damaging	0,58	damaging	0,04	deleterious	3,37	22,9	0,04	0,35	NA	NA	disease	0,61	disease	0,79	disease	0,75	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	-0,26	high_impact	2,08	0,12	0,8	78,16	10,8	P	0,53	P	1	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9229	9229	A	C	MI.6696	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	23	8	Y	S	tAt/tCt	5,91	1	0	probably_damaging	1	neutral	0,37	neutral	2,03	deleterious	-5,01	deleterious	-5,81	medium_impact	3,09	neutral	0,65	damaging	0,09	deleterious	3,58	23,2	0,05	0,35	NA	NA	disease	0,53	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	0,06	medium_impact	1,59	0,15	0,8	78,16	10,8	N	0,51	P	0,96	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9231	9231	C	G	MI.6697	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	25	9	H	D	Cat/Gat	-6,12	0	0	probably_damaging	0,99	neutral	0,2	neutral	1,92	deleterious	-4,23	deleterious	-7,59	high_impact	3,96	neutral	0,6	damaging	0,02	deleterious	3,64	23,2	0,12	0,4	NA	NA	disease	0,68	disease	0,84	disease	0,78	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,79	low_impact	-2,81	medium_impact	-0,15	high_impact	2,37	0,19	0,8	75,1	11,39	N	0,36	N	0,98	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9231	9231	C	A	MI.6698	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	25	9	H	N	Cat/Aat	-6,12	0	0	probably_damaging	0,99	neutral	0,3	neutral	1,92	deleterious	-3,8	deleterious	-5,9	high_impact	3,5	neutral	0,6	damaging	0,02	deleterious	3,9	23,5	0,34	0,5	NA	NA	disease	0,63	disease	0,79	disease	0,75	5	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-2,81	medium_impact	-0,02	medium_impact	1,95	0,13	0,8	75,1	11,39	N	0,31	N	0,96	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9231	9231	C	T	MI.6699	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	25	9	H	Y	Cat/Tat	-6,12	0	0	probably_damaging	0,98	neutral	1	neutral	2,05	neutral	-0,05	deleterious	-5,03	medium_impact	2,29	damaging	0,6	damaging	0,02	deleterious	3,51	23,1	0,35	0,5	NA	NA	disease	0,68	disease	0,74	disease	0,71	4	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,8	low_impact	-2,51	high_impact	1,9	medium_impact	0,87	0,07	0,8	75,1	11,39	N	0,18	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8555	8555	T	A	MI.67	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	29	10	I	N	aTt/aAt	-3,11	0	0	benign	0,01	neutral	0,15	neutral	4,71	neutral	-0,52	neutral	-1,57	low_impact	0,88	neutral	0,85	neutral	0,68	deleterious	2,7	20,8	0,32	0,65	neutral	0,38	disease	0,65	neutral	0,36	disease	0,52	0	neutral	0,85	deleterious	0,57	neutral	-6	neutral	0,17	medium_impact	1,14	medium_impact	-0,13	medium_impact	-0,34	0,45	0,9	27,43	16,7	N	0,39	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8842	8842	A	T	MI.670	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	316	106	I	F	Atc/Ttc	-11,44	0	0,02	possibly_damaging	0,56	neutral	0,41	neutral	4,38	neutral	-0,65	deleterious	-3,03	neutral_impact	-0,04	neutral	0,8	neutral	0,7	deleterious	2,25	17,87	0,44	0,65	neutral	0,29	disease	0,51	neutral	0,29	neutral	0,36	3	neutral	0,61	neutral	0,43	neutral	-3	deleterious	0,52	medium_impact	-0,86	medium_impact	0,2	low_impact	-1,13	0,61	0,9	42,48	7,64	N	0,3	N	0,97	polymorphism	0,99	0,07	rs386829052	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9232	9232	A	G	MI.6700	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	26	9	H	R	cAt/cGt	5,68	1	0	probably_damaging	0,98	neutral	0,34	neutral	1,94	deleterious	-3,77	deleterious	-6,74	high_impact	3,96	neutral	0,69	damaging	0,03	deleterious	2,82	21,5	0,21	0,45	NA	NA	disease	0,68	disease	0,78	disease	0,74	5	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-2,51	medium_impact	0,03	high_impact	2,37	0,13	0,8	75,1	11,39	P	0,57	P	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9232	9232	A	T	MI.6701	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	26	9	H	L	cAt/cTt	5,68	1	0	probably_damaging	0,98	neutral	0,66	neutral	1,95	neutral	-2,47	deleterious	-9,26	high_impact	4,31	damaging	0,58	damaging	0,02	deleterious	3,6	23,2	0,08	0,35	NA	NA	disease	0,7	disease	0,79	disease	0,77	5	deleterious	0,98	neutral	0,34	deleterious	2	deleterious	0,8	low_impact	-2,51	medium_impact	0,36	high_impact	2,68	0,04	0,8	75,1	11,39	P	0,57	P	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9232	9232	A	C	MI.6702	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	26	9	H	P	cAt/cCt	5,68	1	0	probably_damaging	1	neutral	0,21	neutral	1,9	deleterious	-4,82	deleterious	-8,43	high_impact	3,96	damaging	0,57	damaging	0,03	deleterious	3,05	22,4	0,08	0,35	NA	NA	disease	0,7	disease	0,79	disease	0,75	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,14	high_impact	2,37	0,06	0,8	75,1	11,39	P	0,56	P	0,98	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9233	9233	T	A	MI.6703	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	27	9	H	Q	caT/caA	8,69	1	0	probably_damaging	0,99	neutral	0,29	neutral	1,93	deleterious	-3,41	deleterious	-6,74	medium_impact	2,87	neutral	0,64	damaging	0,03	deleterious	3,48	23,1	0,3	0,45	NA	NA	disease	0,65	disease	0,78	disease	0,73	5	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,8	low_impact	-2,81	medium_impact	-0,03	medium_impact	1,39	0,21	0,8	75,1	11,39	P	0,53	P	0,94	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9233	9233	T	G	MI.6704	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	27	9	H	Q	caT/caG	8,69	1	0	probably_damaging	0,99	neutral	0,29	neutral	1,93	deleterious	-3,41	deleterious	-6,74	medium_impact	2,87	neutral	0,64	damaging	0,03	deleterious	3,38	22,9	0,3	0,45	NA	NA	disease	0,65	disease	0,78	disease	0,73	5	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,8	low_impact	-2,81	medium_impact	-0,03	medium_impact	1,39	0,21	0,8	75,1	11,39	P	0,51	P	0,94	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9234	9234	A	G	MI.6705	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	28	10	M	V	Ata/Gta	-1,26	0	0	possibly_damaging	0,54	neutral	0,51	neutral	2,37	neutral	0,43	neutral	-1,95	neutral_impact	0,36	neutral	0,65	neutral	0,47	deleterious	2,35	18,47	0,43	0,55	NA	NA	disease	0,58	neutral	0,47	disease	0,51	0	neutral	0,52	deleterious	0,49	neutral	-3	deleterious	0,47	medium_impact	-0,94	medium_impact	0,2	medium_impact	-0,86	0,17	0,8	73,18	11,92	N	0,27	N	0,96	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9234	9234	A	T	MI.6706	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	28	10	M	L	Ata/Tta	-1,26	0	0	benign	0,42	neutral	0,66	neutral	2,75	neutral	2,09	neutral	-0,38	neutral_impact	-0,86	neutral	0,64	neutral	0,77	neutral	1,16	11,56	0,35	0,5	NA	NA	neutral	0,14	neutral	0,22	neutral	0,23	5	neutral	0,34	deleterious	0,62	neutral	-6	neutral	0,3	medium_impact	-0,73	medium_impact	0,36	low_impact	-1,95	0,21	0,8	73,18	11,92	N	0,39	N	0,95	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9234	9234	A	C	MI.6707	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	28	10	M	L	Ata/Cta	-1,26	0	0	benign	0,42	neutral	0,66	neutral	2,75	neutral	2,09	neutral	-0,38	neutral_impact	-0,86	neutral	0,64	neutral	0,77	neutral	1,06	11,02	0,35	0,5	NA	NA	neutral	0,14	neutral	0,22	neutral	0,23	5	neutral	0,34	deleterious	0,62	neutral	-6	neutral	0,3	medium_impact	-0,73	medium_impact	0,36	low_impact	-1,95	0,21	0,8	73,18	11,92	N	0,39	N	0,95	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9235	9235	T	A	MI.6708	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	29	10	M	K	aTa/aAa	8,92	1	0	possibly_damaging	0,74	neutral	0,29	neutral	2,18	neutral	-2,96	deleterious	-4,24	medium_impact	2,51	neutral	0,61	neutral	0,4	deleterious	3,74	23,3	0,08	0,35	NA	NA	disease	0,71	disease	0,68	disease	0,73	5	neutral	0,8	neutral	0,28	NA	0	deleterious	0,67	low_impact	-1,31	medium_impact	-0,03	medium_impact	1,07	0,1	0,8	73,18	11,92	P	0,61	P	0,99	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9235	9235	T	C	MI.6709	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	29	10	M	T	aTa/aCa	8,92	1	0	possibly_damaging	0,86	neutral	0,39	neutral	2,21	neutral	-1,88	deleterious	-3,75	medium_impact	2,51	neutral	0,61	neutral	0,55	deleterious	2,8	21,4	0,17	0,45	NA	NA	disease	0,69	disease	0,61	disease	0,72	4	neutral	0,86	neutral	0,27	NA	0	deleterious	0,7	low_impact	-1,64	medium_impact	0,08	medium_impact	1,07	0,05	0,8	73,18	11,92	P	0,52	P	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8842	8842	A	G	MI.671	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	316	106	I	V	Atc/Gtc	-11,44	0	0,02	benign	0,01	neutral	0,44	neutral	4,35	neutral	0,47	neutral	-0,46	neutral_impact	-0,59	neutral	0,91	neutral	0,88	neutral	-1,3	0,01	0,52	0,65	neutral	0,3	neutral	0,1	neutral	0,24	neutral	0,24	5	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,09	medium_impact	1,14	medium_impact	0,23	low_impact	-1,6	0,36	0,9	42,48	7,64	N	0,48	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9236	9236	A	C	MI.6710	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	30	10	M	I	atA/atC	5,68	1	0	possibly_damaging	0,63	neutral	0,39	neutral	2,42	neutral	0,72	neutral	-1,5	neutral_impact	-0,02	neutral	0,62	neutral	0,71	deleterious	3,17	22,7	0,35	0,5	NA	NA	neutral	0,46	neutral	0,27	neutral	0,26	5	neutral	0,67	neutral	0,38	neutral	-3	deleterious	0,5	low_impact	-1,09	medium_impact	0,08	low_impact	-1,2	0,21	0,8	73,18	11,92	P	0,59	P	0,95	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9236	9236	A	T	MI.6711	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	30	10	M	I	atA/atT	5,68	1	0	possibly_damaging	0,63	neutral	0,39	neutral	2,42	neutral	0,72	neutral	-1,5	neutral_impact	-0,02	neutral	0,62	neutral	0,71	deleterious	3,33	22,9	0,35	0,5	NA	NA	neutral	0,46	neutral	0,27	neutral	0,26	5	neutral	0,67	neutral	0,38	neutral	-3	deleterious	0,5	low_impact	-1,09	medium_impact	0,08	low_impact	-1,2	0,21	0,8	73,18	11,92	P	0,6	P	0,95	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9237	9237	G	A	MI.6712	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	31	11	V	M	Gta/Ata	7,07	1	0	possibly_damaging	0,55	neutral	0,23	neutral	1,86	deleterious	-3,65	deleterious	-2,57	medium_impact	3,38	neutral	0,64	damaging	0,02	deleterious	3,44	23	0,25	0,45	NA	NA	disease	0,56	disease	0,67	disease	0,66	3	neutral	0,76	neutral	0,34	NA	0	deleterious	0,57	medium_impact	-0,95	medium_impact	-0,11	medium_impact	1,85	0,81	0,85	74,33	12,08	P	0,54	P	0,96	polymorphism	1	0,12	rs1057516064	Likely pathogenic|Likely pathogenic|Likely pathogenic	Developmental_delay|Mitochondrial_encephalopathy|Seizure_Disorders	RCV000408945.1|RCV000408945.1|RCV000408945.1	MedGen|Human_Phenotype_Ontology:MedGen|MedGen	.	.	.	.	.	.	.	.	.	.
chrM	9237	9237	G	T	MI.6713	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	31	11	V	L	Gta/Tta	7,07	1	0	benign	0	neutral	0,74	neutral	2,01	neutral	-1,56	deleterious	-2,56	low_impact	1,74	damaging	0,6	damaging	0,02	neutral	1,55	13,56	0,22	0,45	NA	NA	neutral	0,41	neutral	0,49	neutral	0,17	7	neutral	0,25	deleterious	0,87	neutral	-6	neutral	0,19	high_impact	2,05	medium_impact	0,45	medium_impact	0,38	0,51	0,8	74,33	12,08	N	0,45	N	0,68	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9237	9237	G	C	MI.6714	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	31	11	V	L	Gta/Cta	7,07	1	0	benign	0	neutral	0,74	neutral	2,01	neutral	-1,56	deleterious	-2,56	low_impact	1,74	damaging	0,6	damaging	0,02	neutral	1,39	12,75	0,22	0,45	NA	NA	neutral	0,41	neutral	0,49	neutral	0,17	7	neutral	0,25	deleterious	0,87	neutral	-6	neutral	0,19	high_impact	2,05	medium_impact	0,45	medium_impact	0,38	0,51	0,8	74,33	12,08	N	0,45	N	0,68	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9238	9238	T	G	MI.6715	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	32	11	V	G	gTa/gGa	9,15	1	0	probably_damaging	0,96	neutral	0,32	neutral	1,85	deleterious	-4,23	deleterious	-6	high_impact	4,19	neutral	0,6	damaging	0,07	deleterious	3,59	23,2	0,05	0,35	NA	NA	disease	0,61	disease	0,69	disease	0,68	4	neutral	0,97	neutral	0,18	deleterious	2	deleterious	0,74	low_impact	-2,21	medium_impact	0,01	high_impact	2,57	0,12	0,8	74,33	12,08	P	0,53	P	0,88	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9238	9238	T	C	MI.6716	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	32	11	V	A	gTa/gCa	9,15	1	0	benign	0,3	neutral	0,49	neutral	1,91	neutral	-2,67	deleterious	-3,42	medium_impact	3,38	neutral	0,6	damaging	0,13	deleterious	3,22	22,7	0,22	0,45	NA	NA	neutral	0,45	disease	0,56	neutral	0,41	2	neutral	0,42	deleterious	0,6	neutral	-3	neutral	0,41	medium_impact	-0,51	medium_impact	0,18	medium_impact	1,85	0,18	0,8	74,33	12,08	P	0,56	P	0,39	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9238	9238	T	A	MI.6717	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	32	11	V	E	gTa/gAa	9,15	1	0	probably_damaging	0,92	neutral	0,27	neutral	1,85	deleterious	-3,87	deleterious	-5,14	high_impact	4,19	neutral	0,68	damaging	0,03	deleterious	4,51	24,3	0,05	0,35	NA	NA	disease	0,74	disease	0,77	disease	0,75	5	neutral	0,94	neutral	0,18	deleterious	2	deleterious	0,68	low_impact	-1,9	medium_impact	-0,06	high_impact	2,57	0,13	0,8	74,33	12,08	P	0,62	P	0,96	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9240	9240	A	C	MI.6718	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	34	12	K	Q	Aaa/Caa	-7,04	0	0	probably_damaging	0,99	neutral	0,51	neutral	2,56	neutral	-0,5	neutral	0,54	neutral_impact	-0,3	neutral	0,63	neutral	0,3	deleterious	3,16	22,6	0,43	0,55	NA	NA	neutral	0,31	neutral	0,39	neutral	0,15	7	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,71	low_impact	-2,81	medium_impact	0,2	low_impact	-1,45	0,17	0,8	17,62	42,49	N	0,3	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9240	9240	A	G	MI.6719	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	34	12	K	E	Aaa/Gaa	-7,04	0	0	probably_damaging	0,98	neutral	0,62	neutral	2,67	neutral	0,91	neutral	1,88	neutral_impact	-2,01	neutral	0,73	neutral	0,47	deleterious	2,36	18,58	0,23	0,45	NA	NA	neutral	0,36	neutral	0,16	neutral	0,17	7	neutral	0,98	neutral	0,32	neutral	-2	deleterious	0,72	low_impact	-2,51	medium_impact	0,31	low_impact	-2,98	0,41	0,8	17,62	42,49	N	0,32	N	0,56	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8843	8843	T	C	MI.672	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	317	106	I	T	aTc/aCc	0,36	0,03	0,01	benign	0,28	deleterious	0,04	neutral	4,23	neutral	-1,76	deleterious	-3,71	low_impact	1,8	neutral	0,96	neutral	0,66	deleterious	0,51	7,48	0,47	0,65	disease	0,58	neutral	0,49	neutral	0,38	neutral	0,47	1	neutral	0,95	neutral	0,38	neutral	-2	neutral	0,42	medium_impact	-0,37	medium_impact	-0,49	medium_impact	0,45	0,52	0,9	42,48	7,64	N	0,42	N	0,99	polymorphism	1	0,08	rs386829053	.	.	.	.	.	COSM1138409	.	.	.	.	.	.	.	.
chrM	9241	9241	A	C	MI.6720	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	35	12	K	T	aAa/aCa	4,76	1	0	probably_damaging	0,99	neutral	0,58	neutral	2,57	neutral	-0,21	neutral	-0,34	neutral_impact	-0,48	neutral	0,67	neutral	0,42	neutral	1,43	12,94	0,19	0,45	NA	NA	neutral	0,31	neutral	0,15	neutral	0,17	7	deleterious	0,99	neutral	0,3	neutral	-2	deleterious	0,71	low_impact	-2,81	medium_impact	0,27	low_impact	-1,61	0,1	0,8	17,62	42,49	N	0,47	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9241	9241	A	T	MI.6721	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	35	12	K	M	aAa/aTa	4,76	1	0	probably_damaging	1	neutral	0,27	neutral	2,5	deleterious	-3,43	neutral	-1,85	low_impact	0,85	damaging	0,59	damaging	0,24	deleterious	3,57	23,1	0,12	0,4	NA	NA	neutral	0,3	neutral	0,4	neutral	0,15	7	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,71	low_impact	-3,78	medium_impact	-0,06	medium_impact	-0,42	0,09	0,8	17,62	42,49	P	0,52	P	0,73	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9242	9242	A	T	MI.6722	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	36	12	K	N	aaA/aaT	8,69	1	0,02	probably_damaging	0,99	neutral	0,52	neutral	2,62	neutral	0,41	neutral	1,89	neutral_impact	-1,3	neutral	0,76	neutral	0,95	neutral	1,64	14,06	0,55	0,6	NA	NA	neutral	0,23	neutral	0,14	neutral	0,17	7	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,71	low_impact	-2,81	medium_impact	0,21	low_impact	-2,35	0,21	0,8	17,62	42,49	P	0,56	P	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9242	9242	A	C	MI.6723	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	36	12	K	N	aaA/aaC	8,69	1	0,02	probably_damaging	0,99	neutral	0,52	neutral	2,62	neutral	0,41	neutral	1,89	neutral_impact	-1,3	neutral	0,76	neutral	0,95	neutral	1,56	13,66	0,55	0,6	NA	NA	neutral	0,23	neutral	0,14	neutral	0,17	7	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,71	low_impact	-2,81	medium_impact	0,21	low_impact	-2,35	0,21	0,8	17,62	42,49	P	0,56	P	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9243	9243	C	G	MI.6724	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	37	13	P	A	Ccc/Gcc	-0,33	0,41	0	benign	0,06	neutral	0,44	neutral	2,53	neutral	-1,03	deleterious	-2,55	low_impact	1,73	damaging	0,55	damaging	0,09	neutral	1,06	11,02	0,28	0,45	NA	NA	neutral	0,38	neutral	0,39	neutral	0,19	6	neutral	0,51	deleterious	0,69	neutral	-6	neutral	0,23	medium_impact	0,29	medium_impact	0,13	medium_impact	0,37	0,53	0,8	75,1	11,56	N	0,3	N	0,7	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9243	9243	C	A	MI.6725	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	37	13	P	T	Ccc/Acc	-0,33	0,41	0	benign	0,33	neutral	0,34	neutral	2,5	neutral	-1,35	deleterious	-2,56	medium_impact	2,23	damaging	0,56	damaging	0,05	deleterious	3,43	23	0,24	0,45	NA	NA	disease	0,57	neutral	0,38	disease	0,52	0	neutral	0,59	deleterious	0,51	neutral	-3	neutral	0,39	medium_impact	-0,57	medium_impact	0,03	medium_impact	0,82	0,43	0,8	75,1	11,56	N	0,25	N	0,93	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9243	9243	C	T	MI.6726	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	37	13	P	S	Ccc/Tcc	-0,33	0,41	0	benign	0,02	neutral	0,48	neutral	2,5	neutral	-0,83	neutral	-2,34	medium_impact	2,17	damaging	0,54	damaging	0,05	neutral	1,76	14,76	0,27	0,45	NA	NA	disease	0,54	neutral	0,41	neutral	0,5	0	neutral	0,49	deleterious	0,73	neutral	-3	neutral	0,18	medium_impact	0,77	medium_impact	0,17	medium_impact	0,76	0,15	0,8	75,1	11,56	N	0,27	N	0,79	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9244	9244	C	G	MI.6727	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	38	13	P	R	cCc/cGc	7,3	1	0	possibly_damaging	0,87	neutral	0,35	neutral	2,49	neutral	-1,4	deleterious	-2,7	medium_impact	2,58	damaging	0,49	damaging	0,04	deleterious	3,31	22,9	0,12	0,4	NA	NA	disease	0,71	neutral	0,43	disease	0,54	1	neutral	0,88	neutral	0,24	NA	0	deleterious	0,71	low_impact	-1,67	medium_impact	0,04	medium_impact	1,13	0,34	0,8	75,1	11,56	P	0,5	N	0,93	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9244	9244	C	A	MI.6728	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	38	13	P	H	cCc/cAc	7,3	1	0	probably_damaging	0,92	neutral	0,49	neutral	2,46	neutral	-2,56	neutral	-2,48	medium_impact	3,07	damaging	0,56	damaging	0,03	deleterious	3,89	23,5	0,16	0,45	NA	NA	disease	0,64	neutral	0,48	disease	0,52	0	neutral	0,91	neutral	0,29	deleterious	1	deleterious	0,73	low_impact	-1,9	medium_impact	0,18	medium_impact	1,57	0,21	0,8	75,1	11,56	N	0,46	N	0,88	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9244	9244	C	T	MI.6729	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	38	13	P	L	cCc/cTc	7,3	1	0	possibly_damaging	0,75	neutral	0,57	neutral	2,57	neutral	-1,99	deleterious	-3,13	low_impact	1,59	damaging	0,49	damaging	0,03	deleterious	4,02	23,6	0,15	0,4	NA	NA	disease	0,59	neutral	0,4	neutral	0,45	1	neutral	0,71	neutral	0,41	neutral	-3	deleterious	0,63	low_impact	-1,33	medium_impact	0,26	medium_impact	0,24	0,57	0,8	75,1	11,56	P	0,5	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8843	8843	T	A	MI.673	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	317	106	I	N	aTc/aAc	0,36	0,03	0,01	possibly_damaging	0,85	deleterious	0	neutral	4,19	deleterious	-3,61	deleterious	-5,5	medium_impact	2,85	neutral	0,85	neutral	0,43	deleterious	4,2	23,9	0,27	0,65	disease	0,84	disease	0,74	disease	0,57	disease	0,72	4	deleterious	1	neutral	0,08	deleterious	4	deleterious	0,73	low_impact	-1,47	low_impact	-1,4	medium_impact	1,35	0,54	0,9	42,48	7,64	N	0,29	N	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9246	9246	A	G	MI.6730	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	40	14	S	G	Agc/Ggc	-10,28	0	0	probably_damaging	0,99	neutral	0,25	neutral	1,78	deleterious	-4,49	deleterious	-3,44	high_impact	4,14	damaging	0,57	damaging	0,06	deleterious	3,41	23	0,12	0,4	NA	NA	neutral	0,47	disease	0,8	disease	0,69	4	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,73	low_impact	-2,81	medium_impact	-0,08	high_impact	2,53	0,41	0,8	73,95	11,54	N	0,4	N	0,83	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9246	9246	A	C	MI.6731	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	40	14	S	R	Agc/Cgc	-10,28	0	0	probably_damaging	1	neutral	0,26	neutral	1,77	deleterious	-5	deleterious	-4,3	high_impact	3,94	damaging	0,51	damaging	0,05	deleterious	3,68	23,3	0,05	0,35	NA	NA	disease	0,73	disease	0,82	disease	0,79	6	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,07	high_impact	2,35	0,29	0,8	73,95	11,54	N	0,37	N	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9246	9246	A	T	MI.6732	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	40	14	S	C	Agc/Tgc	-10,28	0	0	probably_damaging	1	neutral	0,13	neutral	1,74	deleterious	-6,69	deleterious	-4,3	high_impact	4,49	neutral	0,61	damaging	0,03	deleterious	3,27	22,8	0,04	0,35	NA	NA	disease	0,63	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	-0,28	high_impact	2,84	0,17	0,8	73,95	11,54	N	0,44	N	0,98	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9247	9247	G	C	MI.6733	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	41	14	S	T	aGc/aCc	8,69	1	0	probably_damaging	0,96	neutral	0,36	neutral	1,95	neutral	-2,32	deleterious	-2,58	high_impact	3,68	damaging	0,57	damaging	0,06	deleterious	3,22	22,7	0,2	0,45	NA	NA	disease	0,56	disease	0,81	disease	0,77	5	neutral	0,96	neutral	0,2	deleterious	2	deleterious	0,71	low_impact	-2,21	medium_impact	0,05	high_impact	2,12	0,49	0,8	73,95	11,54	P	0,61	P	0,63	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9247	9247	G	A	MI.6734	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	41	14	S	N	aGc/aAc	8,69	1	0	probably_damaging	0,96	neutral	0,23	neutral	1,82	deleterious	-3,72	deleterious	-2,57	high_impact	3,8	damaging	0,54	damaging	0,1	deleterious	3,39	23	0,24	0,45	NA	NA	disease	0,62	disease	0,78	disease	0,74	5	neutral	0,97	neutral	0,14	deleterious	2	deleterious	0,73	low_impact	-2,21	medium_impact	-0,11	high_impact	2,22	0,26	0,8	73,95	11,54	P	0,65	P	0,88	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9247	9247	G	T	MI.6735	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	41	14	S	I	aGc/aTc	8,69	1	0	probably_damaging	1	neutral	0,36	neutral	1,75	deleterious	-6,09	deleterious	-5,16	high_impact	4,49	damaging	0,6	damaging	0,03	deleterious	3,94	23,5	0,04	0,35	NA	NA	disease	0,8	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	0,05	high_impact	2,84	0,23	0,8	73,95	11,54	P	0,57	P	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9249	9249	C	A	MI.6736	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	43	15	P	T	Cca/Aca	1,52	1	0	probably_damaging	1	neutral	0,36	neutral	1,87	neutral	-2,95	deleterious	-6,9	high_impact	3,79	neutral	0,63	damaging	0,01	deleterious	3,41	23	0,26	0,45	NA	NA	disease	0,76	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	0,05	high_impact	2,21	0,44	0,8	73,95	11,6	N	0,36	N	0,93	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9249	9249	C	T	MI.6737	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	43	15	P	S	Cca/Tca	1,52	1	0	probably_damaging	1	neutral	0,48	neutral	1,95	neutral	-1,85	deleterious	-6,9	medium_impact	2,98	neutral	0,67	damaging	0,02	deleterious	3,68	23,3	0,26	0,45	NA	NA	disease	0,74	disease	0,62	disease	0,62	2	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,82	low_impact	-3,78	medium_impact	0,17	medium_impact	1,49	0,26	0,8	73,95	11,6	N	0,28	N	0,79	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9249	9249	C	G	MI.6738	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	43	15	P	A	Cca/Gca	1,52	1	0	probably_damaging	0,98	neutral	0,47	neutral	1,92	neutral	-2,23	deleterious	-6,9	medium_impact	3,23	neutral	0,63	damaging	0,03	deleterious	2,8	21,4	0,22	0,45	NA	NA	disease	0,58	disease	0,65	disease	0,65	3	deleterious	0,98	neutral	0,25	deleterious	1	deleterious	0,77	low_impact	-2,51	medium_impact	0,16	medium_impact	1,71	0,46	0,8	73,95	11,6	N	0,33	N	0,7	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9250	9250	C	T	MI.6739	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	44	15	P	L	cCa/cTa	7,3	1	0	probably_damaging	1	neutral	0,62	neutral	1,83	deleterious	-3,84	deleterious	-8,62	medium_impact	3,02	damaging	0,59	damaging	0,02	deleterious	4,16	23,8	0,2	0,45	NA	NA	disease	0,79	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,82	low_impact	-3,78	medium_impact	0,31	medium_impact	1,52	0,58	0,8	73,95	11,6	N	0,4	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8843	8843	T	G	MI.674	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	317	106	I	S	aTc/aGc	0,36	0,03	0,01	possibly_damaging	0,56	deleterious	0	neutral	4,22	neutral	-2,2	deleterious	-4,75	low_impact	1,8	neutral	0,83	neutral	0,44	deleterious	2,66	20,5	0,29	0,65	disease	0,71	disease	0,72	disease	0,56	disease	0,68	4	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,51	medium_impact	-0,86	low_impact	-1,4	medium_impact	0,45	0,45	0,9	42,48	7,64	N	0,32	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9250	9250	C	G	MI.6740	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	44	15	P	R	cCa/cGa	7,3	1	0	probably_damaging	1	neutral	0,32	neutral	1,83	deleterious	-3,78	deleterious	-7,76	medium_impact	3,05	neutral	0,74	damaging	0,02	deleterious	3,35	22,9	0,14	0,4	NA	NA	disease	0,83	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,85	low_impact	-3,78	medium_impact	0,01	medium_impact	1,55	0,27	0,8	73,95	11,6	N	0,42	N	0,93	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9250	9250	C	A	MI.6741	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	44	15	P	Q	cCa/cAa	7,3	1	0	probably_damaging	1	neutral	0,27	neutral	1,83	deleterious	-3,83	deleterious	-6,9	high_impact	3,98	neutral	0,68	damaging	0,02	deleterious	3,9	23,5	0,18	0,45	NA	NA	disease	0,82	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	-0,06	high_impact	2,38	0,22	0,8	73,95	11,6	N	0,49	N	0,86	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9252	9252	T	G	MI.6742	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	46	16	W	G	Tga/Gga	-12,37	0	0	probably_damaging	1	neutral	0,33	neutral	1,79	deleterious	-5,36	deleterious	-11,27	high_impact	4,12	neutral	0,62	damaging	0,02	deleterious	3,68	23,3	0,05	0,35	NA	NA	disease	0,79	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	0,02	high_impact	2,51	0,13	0,8	73,95	11,63	N	0,35	N	0,98	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9252	9252	T	C	MI.6743	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	46	16	W	R	Tga/Cga	-12,37	0	0	probably_damaging	1	neutral	0,35	neutral	1,8	deleterious	-4,86	deleterious	-12,14	high_impact	3,92	neutral	0,74	damaging	0,03	deleterious	3,32	22,9	0,04	0,35	NA	NA	disease	0,87	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	0,04	high_impact	2,33	0,09	0,8	73,95	11,63	N	0,42	N	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9253	9253	G	T	MI.6744	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	47	16	W	L	tGa/tTa	7,53	1	0	probably_damaging	1	neutral	0,65	neutral	1,86	deleterious	-3,02	deleterious	-11,27	medium_impact	2,8	neutral	0,61	damaging	0,02	deleterious	4	23,6	0,06	0,35	NA	NA	disease	0,79	disease	0,74	disease	0,75	5	deleterious	0,99	neutral	0,33	deleterious	1	deleterious	0,81	low_impact	-3,78	medium_impact	0,35	medium_impact	1,33	0,09	0,8	73,95	11,63	N	0,42	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9253	9253	G	C	MI.6745	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	47	16	W	S	tGa/tCa	7,53	1	0	probably_damaging	1	neutral	0,4	neutral	1,81	deleterious	-4,36	deleterious	-12,14	high_impact	4,46	neutral	0,66	damaging	0,03	deleterious	3,76	23,3	0,04	0,35	NA	NA	disease	0,88	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	0,09	high_impact	2,81	0,1	0,8	73,95	11,63	N	0,49	N	0,97	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9254	9254	A	T	MI.6746	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	48	16	W	C	tgA/tgT	9,15	1	0,02	probably_damaging	1	neutral	0,18	neutral	1,78	deleterious	-6,17	deleterious	-11,26	high_impact	4,46	neutral	0,67	damaging	0,02	deleterious	3,89	23,5	0,04	0,35	NA	NA	disease	0,85	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	-0,18	high_impact	2,81	0,14	0,8	73,95	11,63	N	0,49	N	1	polymorphism	1	0,36	rs386829072	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9254	9254	A	C	MI.6747	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	48	16	W	C	tgA/tgC	9,15	1	0,02	probably_damaging	1	neutral	0,18	neutral	1,78	deleterious	-6,17	deleterious	-11,26	high_impact	4,46	neutral	0,67	damaging	0,02	deleterious	3,76	23,3	0,04	0,35	NA	NA	disease	0,85	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	-0,18	high_impact	2,81	0,14	0,8	73,95	11,63	N	0,48	N	1	polymorphism	1	0,36	rs386829072	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9255	9255	C	G	MI.6748	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	49	17	P	A	Ccc/Gcc	1,05	1	0	probably_damaging	0,98	neutral	0,5	neutral	0,61	deleterious	-6,48	deleterious	-6,95	medium_impact	3,41	neutral	0,63	damaging	0,02	deleterious	2,82	21,5	0,07	0,35	NA	NA	disease	0,58	disease	0,68	disease	0,68	4	deleterious	0,98	neutral	0,26	deleterious	1	deleterious	0,78	low_impact	-2,51	medium_impact	0,19	medium_impact	1,87	0,59	0,8	73,95	11,72	N	0,34	N	0,7	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9255	9255	C	A	MI.6749	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	49	17	P	T	Ccc/Acc	1,05	1	0	probably_damaging	1	neutral	0,4	neutral	0,58	deleterious	-7,59	deleterious	-6,95	medium_impact	3,27	neutral	0,63	damaging	0,01	deleterious	3,44	23	0,05	0,35	NA	NA	disease	0,74	disease	0,67	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-3,78	medium_impact	0,09	medium_impact	1,75	0,48	0,8	73,95	11,72	N	0,3	N	0,93	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8844	8844	C	G	MI.675	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	318	106	I	M	atC/atG	4,76	0,83	0,01	possibly_damaging	0,74	neutral	0,2	neutral	4,24	neutral	-1,67	neutral	-2,15	low_impact	1,05	neutral	0,85	neutral	0,45	deleterious	3,09	22,5	0,44	0,65	disease	0,54	neutral	0,43	neutral	0,32	neutral	0,47	1	neutral	0,86	neutral	0,23	neutral	-3	deleterious	0,55	low_impact	-1,19	medium_impact	-0,05	medium_impact	-0,2	0,71	0,9	42,48	7,64	N	0,41	N	0,75	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9255	9255	C	T	MI.6750	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	49	17	P	S	Ccc/Tcc	1,05	1	0	probably_damaging	1	neutral	0,41	neutral	0,6	deleterious	-6,81	deleterious	-6,95	high_impact	3,7	neutral	0,68	damaging	0,02	deleterious	3,71	23,3	0,04	0,35	NA	NA	disease	0,74	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	0,1	high_impact	2,13	0,12	0,8	73,95	11,72	N	0,38	N	0,79	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9256	9256	C	T	MI.6751	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	50	17	P	L	cCc/cTc	5,45	1	0	probably_damaging	1	neutral	0,67	neutral	0,58	deleterious	-7,49	deleterious	-8,69	high_impact	3,96	damaging	0,6	damaging	0,02	deleterious	4,13	23,8	0,03	0,35	NA	NA	disease	0,81	disease	0,64	disease	0,7	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	0,37	high_impact	2,37	0,67	0,85	73,95	11,72	N	0,42	N	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9256	9256	C	G	MI.6752	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	50	17	P	R	cCc/cGc	5,45	1	0	probably_damaging	1	neutral	0,35	neutral	0,58	deleterious	-7,98	deleterious	-7,82	high_impact	4,51	neutral	0,75	damaging	0,02	deleterious	3,38	23	0,03	0,35	NA	NA	disease	0,83	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	0,04	high_impact	2,86	0,25	0,8	73,95	11,72	N	0,49	N	0,93	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9256	9256	C	A	MI.6753	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	50	17	P	H	cCc/cAc	5,45	1	0	probably_damaging	1	neutral	0,54	neutral	0,57	deleterious	-9,26	deleterious	-7,82	high_impact	4,51	neutral	0,61	damaging	0,02	deleterious	3,91	23,5	0,03	0,35	NA	NA	disease	0,79	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	0,23	high_impact	2,86	0,28	0,8	73,95	11,72	N	0,45	N	0,88	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9258	9258	C	A	MI.6754	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	52	18	L	M	Cta/Ata	-11,21	0	0	probably_damaging	1	neutral	0,23	neutral	2	neutral	-2,44	neutral	-1,36	medium_impact	2,69	damaging	0,51	damaging	0,05	deleterious	3,53	23,1	0,28	0,45	NA	NA	neutral	0,39	neutral	0,41	neutral	0,19	6	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	-0,11	medium_impact	1,23	0,63	0,8	75,48	11,59	N	0,35	N	0,85	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9258	9258	C	G	MI.6755	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	52	18	L	V	Cta/Gta	-11,21	0	0	probably_damaging	0,98	neutral	0,51	neutral	2,08	neutral	-0,78	neutral	-1,81	low_impact	1,94	damaging	0,53	damaging	0,06	deleterious	3,22	22,7	0,24	0,45	NA	NA	neutral	0,42	neutral	0,29	neutral	0,22	6	neutral	0,97	neutral	0,27	neutral	-2	deleterious	0,71	low_impact	-2,51	medium_impact	0,2	medium_impact	0,56	0,55	0,8	75,48	11,59	N	0,28	N	0,81	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9259	9259	T	C	MI.6756	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	53	18	L	P	cTa/cCa	-0,33	0	0	probably_damaging	1	neutral	0,31	neutral	1,94	deleterious	-4,75	deleterious	-5,58	high_impact	3,89	damaging	0,45	damaging	0,02	deleterious	3,69	23,3	0,03	0,35	NA	NA	disease	0,77	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	-0,01	high_impact	2,3	0,31	0,8	75,48	11,59	N	0,32	N	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9259	9259	T	G	MI.6757	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	53	18	L	R	cTa/cGa	-0,33	0	0	probably_damaging	1	neutral	0,34	neutral	1,95	deleterious	-4,19	deleterious	-4,89	high_impact	3,89	damaging	0,46	damaging	0,02	deleterious	3,94	23,5	0,02	0,35	NA	NA	disease	0,81	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	0,03	high_impact	2,3	0,19	0,8	75,48	11,59	N	0,34	N	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9259	9259	T	A	MI.6758	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	53	18	L	Q	cTa/cAa	-0,33	0	0	probably_damaging	1	neutral	0,29	neutral	1,95	deleterious	-4,28	deleterious	-4,84	high_impact	3,89	damaging	0,47	damaging	0,02	deleterious	3,86	23,4	0,03	0,35	NA	NA	disease	0,7	disease	0,54	disease	0,65	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	-0,03	high_impact	2,3	0,3	0,8	75,48	11,59	N	0,35	N	0,97	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9261	9261	A	T	MI.6759	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	55	19	T	S	Aca/Tca	-8,2	0	0,01	benign	0,06	neutral	0,43	neutral	2,52	neutral	-0,29	deleterious	-2,76	medium_impact	2,32	neutral	0,66	neutral	0,57	neutral	1,25	11,99	0,32	0,5	NA	NA	neutral	0,33	neutral	0,36	neutral	0,18	6	neutral	0,53	deleterious	0,69	neutral	-3	neutral	0,16	medium_impact	0,29	medium_impact	0,12	medium_impact	0,9	0,7	0,85	75,1	10,9	N	0,38	N	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8844	8844	C	A	MI.676	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	318	106	I	M	atC/atA	4,76	0,83	0,01	possibly_damaging	0,74	neutral	0,2	neutral	4,24	neutral	-1,67	neutral	-2,15	low_impact	1,05	neutral	0,85	neutral	0,45	deleterious	3,53	23,1	0,44	0,65	disease	0,54	neutral	0,43	neutral	0,32	neutral	0,47	1	neutral	0,86	neutral	0,23	neutral	-3	deleterious	0,55	low_impact	-1,19	medium_impact	-0,05	medium_impact	-0,2	0,71	0,9	42,48	7,64	N	0,41	N	0,75	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9261	9261	A	C	MI.6760	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	55	19	T	P	Aca/Cca	-8,2	0	0,01	possibly_damaging	0,48	neutral	0,21	neutral	2,5	neutral	-1,67	deleterious	-4,24	medium_impact	3,12	damaging	0,58	neutral	0,41	deleterious	3,14	22,6	0,07	0,35	NA	NA	disease	0,7	disease	0,53	disease	0,61	2	neutral	0,77	neutral	0,37	NA	0	deleterious	0,6	medium_impact	-0,84	medium_impact	-0,14	medium_impact	1,61	0,43	0,8	75,1	10,9	N	0,37	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9261	9261	A	G	MI.6761	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	55	19	T	A	Aca/Gca	-8,2	0	0,01	benign	0	neutral	0,52	neutral	2,55	neutral	0,45	deleterious	-3,08	medium_impact	2,02	neutral	0,7	neutral	0,75	neutral	1,27	12,12	0,32	0,5	NA	NA	neutral	0,29	neutral	0,36	neutral	0,19	6	neutral	0,47	deleterious	0,76	neutral	-3	neutral	0,12	high_impact	2,05	medium_impact	0,21	medium_impact	0,63	0,4	0,8	75,1	10,9	N	0,38	N	0,44	polymorphism	1	0,07	.	.	.	.	.	pituitary adenoma	.	.	.	.	.	.	.	.	.
chrM	9262	9262	C	T	MI.6762	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	56	19	T	M	aCa/aTa	3,83	0,99	0	possibly_damaging	0,86	neutral	0,23	neutral	2,52	neutral	0,03	deleterious	-3,27	low_impact	1,48	neutral	0,7	neutral	0,66	deleterious	3,68	23,3	0,13	0,4	NA	NA	neutral	0,38	neutral	0,28	neutral	0,21	6	neutral	0,91	neutral	0,19	neutral	-3	deleterious	0,66	low_impact	-1,64	medium_impact	-0,11	medium_impact	0,14	0,63	0,8	75,1	10,9	P	0,5	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9262	9262	C	A	MI.6763	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	56	19	T	K	aCa/aAa	3,83	0,99	0	benign	0,14	neutral	0,29	neutral	2,51	neutral	-1,19	deleterious	-4,11	medium_impact	3,47	neutral	0,64	neutral	0,42	deleterious	3,85	23,4	0,07	0,35	NA	NA	disease	0,64	disease	0,51	disease	0,55	1	neutral	0,66	deleterious	0,58	neutral	-3	deleterious	0,47	medium_impact	-0,1	medium_impact	-0,03	medium_impact	1,93	0,58	0,8	75,1	10,9	P	0,57	P	0,99	polymorphism	1	0,16	rs386829073	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9264	9264	G	C	MI.6764	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	58	20	G	R	Ggg/Cgg	-2,42	0	0	probably_damaging	1	neutral	0,36	neutral	2,28	neutral	-0,96	deleterious	-6,04	high_impact	3,9	neutral	0,63	damaging	0,01	deleterious	3,77	23,4	0,04	0,35	NA	NA	disease	0,72	disease	0,71	disease	0,72	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	0,05	high_impact	2,31	0,63	0,8	74,71	11,58	N	0,29	N	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9264	9264	G	T	MI.6765	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	58	20	G	W	Ggg/Tgg	-2,42	0	0	probably_damaging	1	neutral	0,19	neutral	2,24	deleterious	-3,23	deleterious	-6,31	high_impact	3,9	neutral	0,63	damaging	0,01	deleterious	4,22	23,9	0,06	0,35	NA	NA	disease	0,72	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,17	high_impact	2,31	0,23	0,8	74,71	11,58	N	0,3	N	0,98	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9265	9265	G	T	MI.6766	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	59	20	G	V	gGg/gTg	6,14	1	0	probably_damaging	1	neutral	0,51	neutral	2,46	neutral	1,35	deleterious	-6,71	medium_impact	2,26	damaging	0,53	damaging	0,03	deleterious	3,55	23,1	0,08	0,35	NA	NA	disease	0,57	neutral	0,41	neutral	0,46	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	0,2	medium_impact	0,84	0,2	0,8	74,71	11,58	N	0,41	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9265	9265	G	A	MI.6767	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	59	20	G	E	gGg/gAg	6,14	1	0	probably_damaging	1	neutral	0,28	neutral	2,29	neutral	-0,6	deleterious	-6,01	high_impact	3,56	neutral	0,62	damaging	0,01	deleterious	3,71	23,3	0,04	0,35	NA	NA	disease	0,69	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,04	high_impact	2,01	0,35	0,8	74,71	11,58	P	0,55	P	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9265	9265	G	C	MI.6768	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	59	20	G	A	gGg/gCg	6,14	1	0	probably_damaging	1	neutral	0,53	neutral	2,37	neutral	0,62	deleterious	-3,99	low_impact	1,17	damaging	0,55	damaging	0,1	deleterious	1,82	15,09	0,17	0,45	NA	NA	neutral	0,25	neutral	0,29	neutral	0,2	6	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,73	low_impact	-3,78	medium_impact	0,22	medium_impact	-0,13	0,56	0,8	74,71	11,58	N	0,45	N	0,3	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9267	9267	G	T	MI.6769	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	61	21	A	S	Gcc/Tcc	-1,72	0	0	probably_damaging	0,99	neutral	0,82	neutral	2,58	neutral	0	neutral	-1,15	neutral_impact	-0,06	damaging	0,54	damaging	0,07	deleterious	2,35	18,47	0,25	0,45	NA	NA	neutral	0,07	neutral	0,25	neutral	0,22	6	deleterious	0,99	neutral	0,42	neutral	-2	deleterious	0,69	low_impact	-2,81	medium_impact	0,57	low_impact	-1,24	0,62	0,8	74,33	11,65	N	0,26	N	0,89	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8845	8845	C	T	MI.677	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	319	107	P	S	Ccc/Tcc	-6,58	0	0	probably_damaging	1	neutral	0,15	neutral	4,39	neutral	0,56	deleterious	-7,55	medium_impact	2,24	neutral	0,72	damaging	0,19	deleterious	3,86	23,5	0,49	0,65	neutral	0,38	disease	0,85	disease	0,64	neutral	0,45	1	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	-0,13	medium_impact	0,82	0,28	0,9	48,67	8,6	N	0,28	N	0,82	disease_causing	0,87	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9267	9267	G	C	MI.6770	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	61	21	A	P	Gcc/Ccc	-1,72	0	0	probably_damaging	1	neutral	0,27	neutral	2,22	deleterious	-3,66	deleterious	-3,59	high_impact	3,77	damaging	0,53	damaging	0,03	deleterious	3,62	23,2	0,03	0,35	NA	NA	disease	0,75	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	-0,06	high_impact	2,2	0,71	0,85	74,33	11,65	N	0,33	N	0,99	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	G9267C	MIDD	-	+	Reported	1
chrM	9267	9267	G	A	MI.6771	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	61	21	A	T	Gcc/Acc	-1,72	0	0	probably_damaging	0,99	neutral	0,62	neutral	2,25	neutral	-2,81	neutral	-2,49	medium_impact	2,36	damaging	0,53	damaging	0,03	deleterious	4	23,6	0,11	0,4	NA	NA	neutral	0,46	disease	0,58	neutral	0,44	1	deleterious	0,99	neutral	0,32	deleterious	1	deleterious	0,73	low_impact	-2,81	medium_impact	0,31	medium_impact	0,93	0,78	0,85	74,33	11,65	N	0,24	N	0,86	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9268	9268	C	A	MI.6772	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	62	21	A	D	gCc/gAc	7,3	1	0	probably_damaging	1	neutral	0,21	neutral	2,24	deleterious	-3,09	deleterious	-3,95	high_impact	3,77	damaging	0,55	damaging	0,01	deleterious	4,26	23,9	0,02	0,35	NA	NA	disease	0,76	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,14	high_impact	2,2	0,42	0,8	74,33	11,65	P	0,56	P	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9268	9268	C	T	MI.6773	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	62	21	A	V	gCc/gTc	7,3	1	0	probably_damaging	0,99	neutral	0,63	neutral	2,23	deleterious	-3,26	deleterious	-3,23	medium_impact	2,88	damaging	0,5	damaging	0,03	deleterious	4,3	24	0,07	0,35	NA	NA	disease	0,52	disease	0,59	disease	0,66	3	deleterious	0,99	neutral	0,32	deleterious	1	deleterious	0,75	low_impact	-2,81	medium_impact	0,32	medium_impact	1,4	0,75	0,85	74,33	11,65	P	0,51	P	0,87	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9268	9268	C	G	MI.6774	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	62	21	A	G	gCc/gGc	7,3	1	0	probably_damaging	0,98	neutral	0,82	neutral	2,32	neutral	-1,74	deleterious	-2,54	medium_impact	2,19	damaging	0,5	damaging	0,05	deleterious	3,69	23,3	0,19	0,45	NA	NA	neutral	0,36	neutral	0,34	neutral	0,17	7	neutral	0,97	neutral	0,42	deleterious	1	deleterious	0,71	low_impact	-2,51	medium_impact	0,57	medium_impact	0,78	0,7	0,85	74,33	11,65	N	0,47	N	0,67	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9270	9270	C	G	MI.6775	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	64	22	L	V	Ctc/Gtc	-9,82	0	0	benign	0,1	neutral	0,54	neutral	2,31	neutral	-0,05	neutral	0,02	neutral_impact	0,07	neutral	0,75	neutral	0,81	deleterious	-0,02	2,44	0,3	0,45	NA	NA	neutral	0,12	neutral	0,25	neutral	0,24	5	neutral	0,38	deleterious	0,72	neutral	-6	neutral	0,12	medium_impact	0,06	medium_impact	0,23	low_impact	-1,12	0,75	0,85	69,35	10,21	N	0,39	N	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9270	9270	C	A	MI.6776	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	64	22	L	I	Ctc/Atc	-9,82	0	0	benign	0,23	neutral	0,5	neutral	2,31	neutral	-0,05	neutral	0,24	neutral_impact	-0,22	neutral	0,77	neutral	0,81	neutral	0,92	10,22	0,34	0,5	NA	NA	neutral	0,04	neutral	0,16	neutral	0,18	6	neutral	0,4	deleterious	0,64	neutral	-6	neutral	0,14	medium_impact	-0,36	medium_impact	0,19	low_impact	-1,38	0,61	0,8	69,35	10,21	N	0,5	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9270	9270	C	T	MI.6777	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	64	22	L	F	Ctc/Ttc	-9,82	0	0	benign	0,01	neutral	0,68	neutral	2,22	neutral	-0,74	neutral	-1,03	neutral_impact	0,7	neutral	0,78	neutral	0,77	deleterious	0,76	9,23	0,29	0,45	NA	NA	neutral	0,15	neutral	0,21	neutral	0,22	6	neutral	0,29	deleterious	0,84	neutral	-6	neutral	0,09	medium_impact	1,07	medium_impact	0,38	medium_impact	-0,56	0,74	0,85	69,35	10,21	N	0,34	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9271	9271	T	A	MI.6778	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	65	22	L	H	cTc/cAc	-0,8	0	0	probably_damaging	0,91	neutral	0,46	neutral	2,08	deleterious	-3,91	deleterious	-3,03	medium_impact	2,98	neutral	0,69	neutral	0,48	deleterious	3,85	23,4	0,04	0,35	NA	NA	neutral	0,43	disease	0,53	neutral	0,39	2	neutral	0,91	neutral	0,28	deleterious	1	deleterious	0,67	low_impact	-1,85	medium_impact	0,15	medium_impact	1,49	0,33	0,8	69,35	10,21	N	0,35	N	0,84	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9271	9271	T	G	MI.6779	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	65	22	L	R	cTc/cGc	-0,8	0	0	possibly_damaging	0,83	neutral	0,29	neutral	2,09	deleterious	-3,26	deleterious	-2,8	medium_impact	2,98	neutral	0,61	neutral	0,43	deleterious	3,94	23,5	0,02	0,35	NA	NA	disease	0,61	disease	0,65	disease	0,72	4	neutral	0,87	neutral	0,23	NA	0	deleterious	0,7	low_impact	-1,54	medium_impact	-0,03	medium_impact	1,49	0,36	0,8	69,35	10,21	N	0,36	N	0,99	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8845	8845	C	A	MI.678	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	319	107	P	T	Ccc/Acc	-6,58	0	0	probably_damaging	1	neutral	0,16	neutral	4,37	neutral	1,03	deleterious	-7,56	medium_impact	2,07	neutral	0,67	damaging	0,16	deleterious	3,65	23,2	0,32	0,65	neutral	0,36	disease	0,84	disease	0,61	neutral	0,45	1	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	-0,12	medium_impact	0,68	0,84	0,9	48,67	8,6	N	0,27	N	0,93	disease_causing	0,86	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9271	9271	T	C	MI.6780	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	65	22	L	P	cTc/cCc	-0,8	0	0	probably_damaging	0,94	neutral	0,29	neutral	2,08	deleterious	-3,89	deleterious	-3,06	medium_impact	2,63	damaging	0,56	neutral	0,36	deleterious	3,65	23,2	0,02	0,35	NA	NA	disease	0,66	disease	0,66	disease	0,72	4	neutral	0,95	neutral	0,18	deleterious	1	deleterious	0,75	low_impact	-2,03	medium_impact	-0,03	medium_impact	1,17	0,4	0,8	69,35	10,21	N	0,31	N	0,83	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9273	9273	T	G	MI.6781	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	67	23	S	A	Tca/Gca	-9,13	0	0	probably_damaging	0,96	neutral	0,63	neutral	2,23	neutral	-0,49	neutral	-0,16	neutral_impact	0	neutral	0,63	neutral	0,56	deleterious	0,77	9,28	0,24	0,45	NA	NA	neutral	0,09	neutral	0,28	neutral	0,24	5	neutral	0,95	neutral	0,34	neutral	-2	deleterious	0,54	low_impact	-2,21	medium_impact	0,32	low_impact	-1,18	0,52	0,8	74,33	11,74	N	0,35	N	0,4	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9273	9273	T	C	MI.6782	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	67	23	S	P	Tca/Cca	-9,13	0	0	probably_damaging	0,99	neutral	0,22	neutral	2,01	deleterious	-3,51	deleterious	-2,51	medium_impact	2,54	damaging	0,39	damaging	0,1	deleterious	3,76	23,4	0,05	0,35	NA	NA	disease	0,79	disease	0,68	disease	0,75	5	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,78	low_impact	-2,81	medium_impact	-0,12	medium_impact	1,09	0,37	0,8	74,33	11,74	N	0,36	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9273	9273	T	A	MI.6783	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	67	23	S	T	Tca/Aca	-9,13	0	0	probably_damaging	0,92	neutral	0,4	neutral	2,07	neutral	-1,94	neutral	-1,74	medium_impact	2	damaging	0,51	damaging	0,19	deleterious	3,44	23	0,21	0,45	NA	NA	neutral	0,27	disease	0,56	neutral	0,36	3	neutral	0,92	neutral	0,24	deleterious	1	deleterious	0,63	low_impact	-1,9	medium_impact	0,09	medium_impact	0,61	0,64	0,8	74,33	11,74	N	0,39	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9274	9274	C	T	MI.6784	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	68	23	S	L	tCa/tTa	4,52	1	0	probably_damaging	0,99	neutral	0,73	neutral	2,04	neutral	-2,51	deleterious	-3,61	medium_impact	2,89	damaging	0,43	damaging	0,07	deleterious	4,47	24,2	0,05	0,35	NA	NA	disease	0,63	disease	0,52	disease	0,6	2	deleterious	0,99	neutral	0,37	deleterious	1	deleterious	0,74	low_impact	-2,81	medium_impact	0,44	medium_impact	1,41	0,57	0,8	74,33	11,74	P	0,59	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9274	9274	C	G	MI.6785	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	68	23	S	W	tCa/tGa	4,52	1	0	probably_damaging	1	neutral	0,2	neutral	1,98	deleterious	-5,9	deleterious	-3,41	medium_impact	3,24	damaging	0,44	damaging	0,09	deleterious	4,15	23,8	0,06	0,35	NA	NA	disease	0,74	disease	0,56	disease	0,7	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,76	low_impact	-3,78	medium_impact	-0,15	medium_impact	1,72	0,19	0,8	74,33	11,74	N	0,49	N	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9276	9276	G	A	MI.6786	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	70	24	A	T	Gcc/Acc	-5,66	0	0	benign	0,02	neutral	0,42	neutral	2,46	neutral	-1,27	deleterious	-2,71	medium_impact	2,6	damaging	0,51	neutral	0,75	deleterious	2,07	16,65	0,18	0,45	NA	NA	neutral	0,48	neutral	0,32	neutral	0,32	4	neutral	0,56	deleterious	0,7	neutral	-3	neutral	0,16	medium_impact	0,77	medium_impact	0,11	medium_impact	1,15	0,74	0,85	74,71	11,6	N	0,5	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9276	9276	G	T	MI.6787	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	70	24	A	S	Gcc/Tcc	-5,66	0	0	benign	0,34	neutral	0,44	neutral	2,44	neutral	-1,21	neutral	-2,02	low_impact	1,86	damaging	0,59	neutral	0,71	deleterious	2,18	17,39	0,26	0,45	NA	NA	neutral	0,48	neutral	0,31	neutral	0,29	4	neutral	0,48	deleterious	0,55	neutral	-6	neutral	0,27	medium_impact	-0,59	medium_impact	0,13	medium_impact	0,48	0,37	0,8	74,71	11,6	N	0,39	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9276	9276	G	C	MI.6788	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	70	24	A	P	Gcc/Ccc	-5,66	0	0	possibly_damaging	0,8	neutral	0,22	neutral	2,42	neutral	-2,88	deleterious	-3,94	high_impact	3,96	damaging	0,57	neutral	0,43	deleterious	3,61	23,2	0,04	0,35	NA	NA	disease	0,77	disease	0,67	disease	0,7	4	neutral	0,87	neutral	0,21	deleterious	1	deleterious	0,74	low_impact	-1,45	medium_impact	-0,12	high_impact	2,37	0,65	0,8	74,71	11,6	N	0,42	N	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9277	9277	C	G	MI.6789	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	71	24	A	G	gCc/gGc	3,6	1	0	benign	0,21	neutral	0,41	neutral	2,43	neutral	-2,23	deleterious	-3,12	medium_impact	1,97	damaging	0,59	neutral	0,78	deleterious	3,5	23,1	0,24	0,45	NA	NA	neutral	0,38	neutral	0,3	neutral	0,19	6	neutral	0,51	deleterious	0,6	neutral	-3	neutral	0,26	medium_impact	-0,31	medium_impact	0,1	medium_impact	0,58	0,75	0,85	74,71	11,6	P	0,52	P	0,67	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8845	8845	C	G	MI.679	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	319	107	P	A	Ccc/Gcc	-6,58	0	0	probably_damaging	1	deleterious	0,02	neutral	4,35	neutral	0,92	deleterious	-7,56	medium_impact	2,98	neutral	0,66	damaging	0,17	deleterious	3,06	22,4	0,35	0,65	disease	0,51	disease	0,77	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,76	low_impact	-3,6	medium_impact	-0,66	medium_impact	1,46	0,75	0,9	48,67	8,6	N	0,28	N	0,79	disease_causing	0,8	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9277	9277	C	A	MI.6790	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	71	24	A	D	gCc/gAc	3,6	1	0	possibly_damaging	0,68	neutral	0,2	neutral	2,4	neutral	-2,8	deleterious	-4,63	high_impact	3,61	damaging	0,59	neutral	0,48	deleterious	4,36	24,1	0,02	0,35	NA	NA	disease	0,8	disease	0,65	disease	0,7	4	neutral	0,83	neutral	0,26	deleterious	1	deleterious	0,69	low_impact	-1,19	medium_impact	-0,15	high_impact	2,05	0,46	0,8	74,71	11,6	P	0,53	P	0,99	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9277	9277	C	T	MI.6791	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	71	24	A	V	gCc/gTc	3,6	1	0	benign	0,24	neutral	0,52	neutral	2,52	neutral	-0,55	deleterious	-3,13	low_impact	1,72	damaging	0,54	neutral	0,77	deleterious	4	23,6	0,19	0,45	NA	NA	neutral	0,49	neutral	0,33	neutral	0,33	3	neutral	0,37	deleterious	0,64	neutral	-6	deleterious	0,48	medium_impact	-0,38	medium_impact	0,21	medium_impact	0,36	0,74	0,85	74,71	11,6	P	0,51	P	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9279	9279	C	T	MI.6792	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	73	25	L	F	Ctc/Ttc	-2,19	0	0	benign	0,02	neutral	0,85	neutral	2,45	neutral	-0,79	neutral	-1,34	neutral_impact	0,54	neutral	0,74	neutral	0,92	deleterious	0,52	7,6	0,38	0,5	NA	NA	neutral	0,15	neutral	0,27	neutral	0,22	6	neutral	0,09	deleterious	0,92	neutral	-6	neutral	0,12	medium_impact	0,77	medium_impact	0,62	medium_impact	-0,7	0,52	0,8	23,37	18,52	N	0,32	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9279	9279	C	A	MI.6793	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	73	25	L	I	Ctc/Atc	-2,19	0	0	benign	0,34	neutral	0,49	neutral	2,4	neutral	-1,75	neutral	-1,16	medium_impact	2,67	neutral	0,66	damaging	0,1	deleterious	3,54	23,1	0,33	0,5	NA	NA	disease	0,51	neutral	0,44	neutral	0,46	1	neutral	0,43	deleterious	0,58	neutral	-3	neutral	0,23	medium_impact	-0,59	medium_impact	0,18	medium_impact	1,21	0,55	0,8	23,37	18,52	N	0,27	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9279	9279	C	G	MI.6794	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	73	25	L	V	Ctc/Gtc	-2,19	0	0	benign	0,16	neutral	0,56	neutral	2,41	neutral	-1,57	neutral	-1,77	medium_impact	2,56	neutral	0,61	damaging	0,07	neutral	1,55	13,6	0,33	0,5	NA	NA	neutral	0,38	disease	0,54	neutral	0,38	2	neutral	0,33	deleterious	0,7	neutral	-3	neutral	0,18	medium_impact	-0,17	medium_impact	0,25	medium_impact	1,11	0,66	0,8	23,37	18,52	N	0,22	N	0,55	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9280	9280	T	C	MI.6795	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	74	25	L	P	cTc/cCc	0,59	0,07	0	probably_damaging	1	neutral	0,3	neutral	2,34	deleterious	-4,61	deleterious	-4,91	high_impact	3,57	damaging	0,52	damaging	0,02	deleterious	3,7	23,3	0,02	0,35	NA	NA	disease	0,8	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,02	high_impact	2,02	0,46	0,8	23,37	18,52	N	0,33	N	0,91	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9280	9280	T	G	MI.6796	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	74	25	L	R	cTc/cGc	0,59	0,07	0	probably_damaging	0,99	neutral	0,33	neutral	2,36	deleterious	-3,91	deleterious	-4,04	high_impact	3,92	damaging	0,54	damaging	0,02	deleterious	3,99	23,6	0,02	0,35	NA	NA	disease	0,82	disease	0,68	disease	0,72	4	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-2,81	medium_impact	0,02	high_impact	2,33	0,28	0,8	23,37	18,52	N	0,35	N	0,99	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9280	9280	T	A	MI.6797	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	74	25	L	H	cTc/cAc	0,59	0,07	0	probably_damaging	0,99	neutral	0,55	neutral	2,33	deleterious	-4,55	deleterious	-4,39	high_impact	3,92	neutral	0,61	damaging	0,05	deleterious	3,91	23,5	0,04	0,35	NA	NA	disease	0,66	disease	0,64	disease	0,68	4	deleterious	0,99	neutral	0,28	deleterious	2	deleterious	0,74	low_impact	-2,81	medium_impact	0,24	high_impact	2,33	0,28	0,8	23,37	18,52	N	0,28	N	0,87	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9282	9282	C	G	MI.6798	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	76	26	L	V	Cta/Gta	-16,07	0	0	benign	0,08	neutral	0,46	neutral	2,5	neutral	-0,46	neutral	-0,56	low_impact	1,27	neutral	0,68	neutral	0,63	deleterious	0,51	7,54	0,25	0,45	NA	NA	neutral	0,21	neutral	0,19	neutral	0,19	6	neutral	0,48	deleterious	0,69	neutral	-6	neutral	0,17	medium_impact	0,16	medium_impact	0,15	medium_impact	-0,04	0,52	0,8	75,1	11,41	N	0,51	P	0,81	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9282	9282	C	A	MI.6799	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	76	26	L	M	Cta/Ata	-16,07	0	0	possibly_damaging	0,81	neutral	0,52	neutral	2,44	neutral	-1,92	neutral	-0,04	low_impact	0,9	neutral	0,71	neutral	0,71	deleterious	2,26	17,89	0,23	0,45	NA	NA	neutral	0,19	neutral	0,18	neutral	0,21	6	neutral	0,78	neutral	0,36	neutral	-3	deleterious	0,62	low_impact	-1,48	medium_impact	0,21	medium_impact	-0,38	0,51	0,8	75,1	11,41	N	0,45	N	0,85	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8556	8556	T	A	MI.68	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	30	10	I	M	atT/atA	-0,33	0	0	benign	0,04	neutral	0,29	neutral	4,68	neutral	-1,06	neutral	0,07	neutral_impact	0,21	neutral	0,9	neutral	0,93	deleterious	8,35	35	0,43	0,65	disease	0,6	neutral	0,09	neutral	0,18	neutral	0,36	3	neutral	0,69	deleterious	0,63	neutral	-6	neutral	0,19	medium_impact	0,55	medium_impact	0,07	medium_impact	-0,92	0,4	0,9	27,43	16,7	P	0,59	P	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8846	8846	C	T	MI.680	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	320	107	P	L	cCc/cTc	5,68	1	0	probably_damaging	1	neutral	0,07	neutral	4,49	neutral	1,8	deleterious	-9,45	medium_impact	2,6	damaging	0,59	damaging	0,13	deleterious	4,4	24,1	0,44	0,65	neutral	0,27	disease	0,91	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	-0,34	medium_impact	1,13	0,78	0,9	48,67	8,6	N	0,43	N	0,95	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9283	9283	T	G	MI.6800	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	77	26	L	R	cTa/cGa	-0,33	0	0	possibly_damaging	0,52	neutral	0,26	neutral	2,43	deleterious	-3,12	deleterious	-2,66	medium_impact	3,15	damaging	0,55	neutral	0,3	deleterious	3,9	23,5	0,03	0,35	NA	NA	disease	0,78	neutral	0,49	disease	0,63	3	neutral	0,72	neutral	0,37	NA	0	deleterious	0,65	medium_impact	-0,9	medium_impact	-0,07	medium_impact	1,64	0,23	0,8	75,1	11,41	N	0,35	N	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9283	9283	T	C	MI.6801	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	77	26	L	P	cTa/cCa	-0,33	0	0	possibly_damaging	0,82	neutral	0,22	neutral	2,42	deleterious	-3,5	deleterious	-3,12	medium_impact	2,81	damaging	0,55	neutral	0,34	deleterious	3,67	23,3	0,02	0,35	NA	NA	disease	0,79	disease	0,51	disease	0,65	3	neutral	0,88	neutral	0,2	NA	0	deleterious	0,72	low_impact	-1,51	medium_impact	-0,12	medium_impact	1,34	0,26	0,8	75,1	11,41	N	0,34	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9283	9283	T	A	MI.6802	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	77	26	L	Q	cTa/cAa	-0,33	0	0	possibly_damaging	0,67	neutral	0,22	neutral	2,41	deleterious	-3,25	neutral	-2,44	medium_impact	3,15	neutral	0,64	neutral	0,35	deleterious	3,81	23,4	0,04	0,35	NA	NA	disease	0,57	neutral	0,34	neutral	0,49	0	neutral	0,81	neutral	0,28	NA	0	deleterious	0,62	low_impact	-1,17	medium_impact	-0,12	medium_impact	1,64	0,24	0,8	75,1	11,41	N	0,41	N	0,97	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9285	9285	A	T	MI.6803	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	79	27	M	L	Atg/Ttg	-4,73	0	0	benign	0	neutral	0,99	neutral	2,43	neutral	0,67	neutral	0,59	neutral_impact	-0,93	neutral	0,79	neutral	0,96	neutral	-1,39	0	0,26	0,45	NA	NA	neutral	0,27	neutral	0,31	neutral	0,2	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,05	medium_impact	1,33	low_impact	-2,02	0,36	0,8	20,69	18,51	N	0,25	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9285	9285	A	G	MI.6804	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	79	27	M	V	Atg/Gtg	-4,73	0	0	benign	0,01	neutral	0,62	neutral	2,37	neutral	0,17	neutral	-0,88	low_impact	1,38	neutral	0,75	neutral	0,63	deleterious	0,64	8,46	0,22	0,45	NA	NA	disease	0,6	neutral	0,43	neutral	0,48	0	neutral	0,37	deleterious	0,81	neutral	-6	neutral	0,16	medium_impact	1,07	medium_impact	0,31	medium_impact	0,05	0,41	0,8	20,69	18,51	N	0,25	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9285	9285	A	C	MI.6805	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	79	27	M	L	Atg/Ctg	-4,73	0	0	benign	0	neutral	0,99	neutral	2,43	neutral	0,67	neutral	0,59	neutral_impact	-0,93	neutral	0,79	neutral	0,96	neutral	-1,41	0	0,26	0,45	NA	NA	neutral	0,27	neutral	0,31	neutral	0,2	6	neutral	0,01	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,05	medium_impact	1,33	low_impact	-2,02	0,36	0,8	20,69	18,51	N	0,25	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9286	9286	T	C	MI.6806	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	80	27	M	T	aTg/aCg	-1,26	0	0	benign	0	neutral	0,87	neutral	2,33	neutral	-0,37	neutral	-1,7	neutral_impact	0,68	neutral	0,72	neutral	0,75	neutral	-0,77	0,05	0,12	0,4	NA	NA	neutral	0,39	neutral	0,41	neutral	0,17	7	neutral	0,13	deleterious	0,94	neutral	-6	neutral	0,14	high_impact	2,05	medium_impact	0,66	medium_impact	-0,57	0,19	0,8	20,69	18,51	N	0,31	N	0,05	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9286	9286	T	A	MI.6807	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	80	27	M	K	aTg/aAg	-1,26	0	0	benign	0,02	neutral	0,32	neutral	2,26	neutral	-2,15	deleterious	-3,25	medium_impact	2,64	neutral	0,65	neutral	0,36	deleterious	2,03	16,41	0,03	0,35	NA	NA	disease	0,82	disease	0,68	disease	0,78	6	neutral	0,67	deleterious	0,65	neutral	-3	neutral	0,23	medium_impact	0,77	medium_impact	0,01	medium_impact	1,18	0,31	0,8	20,69	18,51	N	0,3	N	0,83	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9287	9287	G	C	MI.6808	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	81	27	M	I	atG/atC	4,76	0,7	0,01	benign	0,01	neutral	0,48	neutral	2,34	neutral	0,06	neutral	-0,46	neutral_impact	0,76	neutral	0,74	neutral	0,75	deleterious	0,32	5,84	0,27	0,45	NA	NA	disease	0,65	neutral	0,38	neutral	0,48	0	neutral	0,51	deleterious	0,74	neutral	-6	neutral	0,18	medium_impact	1,07	medium_impact	0,17	medium_impact	-0,5	0,35	0,8	20,69	18,51	N	0,37	N	0,23	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9287	9287	G	T	MI.6809	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	81	27	M	I	atG/atT	4,76	0,7	0,01	benign	0,01	neutral	0,48	neutral	2,34	neutral	0,06	neutral	-0,46	neutral_impact	0,76	neutral	0,74	neutral	0,75	deleterious	0,48	7,25	0,27	0,45	NA	NA	disease	0,65	neutral	0,38	neutral	0,48	0	neutral	0,51	deleterious	0,74	neutral	-6	neutral	0,18	medium_impact	1,07	medium_impact	0,17	medium_impact	-0,5	0,35	0,8	20,69	18,51	N	0,36	N	0,23	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8846	8846	C	A	MI.681	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	320	107	P	H	cCc/cAc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	4,29	neutral	-1,99	deleterious	-8,5	high_impact	3,92	neutral	0,63	damaging	0,11	deleterious	4,03	23,6	0,3	0,65	disease	0,79	disease	0,89	disease	0,72	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,6	low_impact	-1,4	high_impact	2,26	0,64	0,9	48,67	8,6	N	0,49	N	0,64	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9288	9288	A	T	MI.6810	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	82	28	T	S	Acc/Tcc	-3,34	0	0	probably_damaging	0,98	neutral	0,47	neutral	2,46	neutral	-1,69	deleterious	-2,96	medium_impact	3,03	damaging	0,6	neutral	0,51	deleterious	2,82	21,5	0,31	0,45	NA	NA	disease	0,63	disease	0,56	disease	0,58	2	neutral	0,97	neutral	0,25	deleterious	1	deleterious	0,72	low_impact	-2,51	medium_impact	0,16	medium_impact	1,53	0,75	0,85	75,48	11,24	N	0,33	N	0,77	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9288	9288	A	C	MI.6811	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	82	28	T	P	Acc/Ccc	-3,34	0	0	probably_damaging	1	neutral	0,2	neutral	2,45	neutral	-2,11	deleterious	-4,6	medium_impact	2,63	damaging	0,57	neutral	0,66	deleterious	3,23	22,8	0,07	0,35	NA	NA	disease	0,87	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,82	low_impact	-3,78	medium_impact	-0,15	medium_impact	1,17	0,46	0,8	75,48	11,24	N	0,35	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9288	9288	A	G	MI.6812	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	82	28	T	A	Acc/Gcc	-3,34	0	0	probably_damaging	0,98	neutral	0,51	neutral	2,54	neutral	-0,47	deleterious	-3,42	low_impact	0,84	neutral	0,68	neutral	0,81	neutral	1,77	14,83	0,27	0,45	NA	NA	neutral	0,41	neutral	0,37	neutral	0,17	7	neutral	0,97	neutral	0,27	neutral	-2	deleterious	0,7	low_impact	-2,51	medium_impact	0,2	medium_impact	-0,43	0,46	0,8	75,48	11,24	N	0,3	N	0,44	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9289	9289	C	A	MI.6813	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	83	28	T	N	aCc/aAc	6,84	1	0	probably_damaging	1	neutral	0,3	neutral	2,44	neutral	-2,49	deleterious	-3,94	medium_impact	3,48	neutral	0,64	neutral	0,43	deleterious	3,43	23	0,25	0,45	NA	NA	disease	0,81	disease	0,6	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-3,78	medium_impact	-0,02	medium_impact	1,94	0,65	0,8	75,48	11,24	P	0,54	P	0,89	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9289	9289	C	T	MI.6814	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	83	28	T	I	aCc/aTc	6,84	1	0	probably_damaging	1	neutral	0,41	neutral	2,5	neutral	-0,95	deleterious	-4,14	medium_impact	2,52	neutral	0,65	neutral	0,53	deleterious	3,76	23,3	0,13	0,4	NA	NA	disease	0,87	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,79	low_impact	-3,78	medium_impact	0,1	medium_impact	1,08	0,7	0,85	75,48	11,24	N	0,47	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9289	9289	C	G	MI.6815	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	83	28	T	S	aCc/aGc	6,84	1	0	probably_damaging	0,98	neutral	0,47	neutral	2,46	neutral	-1,69	deleterious	-2,96	medium_impact	3,03	damaging	0,6	neutral	0,51	deleterious	3,02	22,3	0,31	0,45	NA	NA	disease	0,63	disease	0,56	disease	0,58	2	neutral	0,97	neutral	0,25	deleterious	1	deleterious	0,72	low_impact	-2,51	medium_impact	0,16	medium_impact	1,53	0,75	0,85	75,48	11,24	P	0,54	P	0,77	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9291	9291	T	G	MI.6816	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	85	29	S	A	Tcc/Gcc	-3,11	0	0	probably_damaging	0,98	neutral	0,53	neutral	2,29	neutral	0,46	neutral	-1,27	low_impact	1,46	neutral	0,62	damaging	0,22	deleterious	3,46	23	0,31	0,5	NA	NA	disease	0,53	neutral	0,39	neutral	0,45	1	neutral	0,97	neutral	0,28	neutral	-2	deleterious	0,66	low_impact	-2,51	medium_impact	0,22	medium_impact	0,13	0,61	0,8	75,1	11,48	N	0,24	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9291	9291	T	C	MI.6817	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	85	29	S	P	Tcc/Ccc	-3,11	0	0	probably_damaging	1	neutral	0,21	neutral	2,21	neutral	-1,97	deleterious	-2,9	medium_impact	3,48	damaging	0,58	damaging	0,04	deleterious	3,8	23,4	0,06	0,35	NA	NA	disease	0,9	disease	0,58	disease	0,76	5	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,83	low_impact	-3,78	medium_impact	-0,14	medium_impact	1,94	0,35	0,8	75,1	11,48	N	0,28	N	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9291	9291	T	A	MI.6818	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	85	29	S	T	Tcc/Acc	-3,11	0	0	probably_damaging	0,96	neutral	0,45	neutral	2,29	neutral	0,21	neutral	-0,67	low_impact	1,23	neutral	0,7	damaging	0,28	deleterious	2,38	18,71	0,3	0,45	NA	NA	neutral	0,39	neutral	0,28	neutral	0,2	6	neutral	0,96	neutral	0,25	neutral	-2	deleterious	0,68	low_impact	-2,21	medium_impact	0,14	medium_impact	-0,08	0,68	0,85	75,1	11,48	N	0,37	N	0,63	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9292	9292	C	G	MI.6819	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	86	29	S	C	tCc/tGc	5,68	1	0	probably_damaging	1	neutral	0,18	neutral	2,21	neutral	-1,87	deleterious	-2,54	medium_impact	2,93	neutral	0,62	damaging	0,18	deleterious	3,38	22,9	0,09	0,35	NA	NA	disease	0,82	neutral	0,36	disease	0,67	3	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,76	low_impact	-3,78	medium_impact	-0,18	medium_impact	1,44	0,43	0,8	75,1	11,48	N	0,47	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8846	8846	C	G	MI.682	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	320	107	P	R	cCc/cGc	5,68	1	0	probably_damaging	1	deleterious	0	neutral	4,3	neutral	-1,46	deleterious	-8,51	high_impact	3,92	damaging	0,6	damaging	0,12	deleterious	3,59	23,2	0,25	0,65	neutral	0,43	disease	0,94	disease	0,76	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,6	low_impact	-1,4	high_impact	2,26	0,65	0,9	48,67	8,6	P	0,53	P	0,65	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9292	9292	C	T	MI.6820	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	86	29	S	F	tCc/tTc	5,68	1	0	probably_damaging	1	neutral	0,72	neutral	2,24	neutral	0,62	deleterious	-3,01	low_impact	1,49	neutral	0,64	damaging	0,17	deleterious	4,02	23,6	0,07	0,35	NA	NA	disease	0,8	neutral	0,34	disease	0,51	0	deleterious	1	neutral	0,36	neutral	-2	deleterious	0,78	low_impact	-3,78	medium_impact	0,43	medium_impact	0,15	0,32	0,8	75,1	11,48	N	0,4	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9292	9292	C	A	MI.6821	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	86	29	S	Y	tCc/tAc	5,68	1	0	probably_damaging	1	neutral	1	neutral	2,22	neutral	-0,2	deleterious	-3,12	low_impact	1,82	neutral	0,62	damaging	0,05	deleterious	3,84	23,4	0,06	0,35	NA	NA	disease	0,87	neutral	0,42	disease	0,75	5	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,79	low_impact	-3,78	high_impact	1,9	medium_impact	0,45	0,36	0,8	75,1	11,48	N	0,35	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9294	9294	G	A	MI.6822	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	88	30	G	S	Ggc/Agc	-11,9	0	0	probably_damaging	1	neutral	0,41	neutral	2,29	neutral	-2,61	deleterious	-5,33	low_impact	1,79	damaging	0,46	damaging	0,04	deleterious	3,98	23,6	0,08	0,35	NA	NA	disease	0,59	neutral	0,47	neutral	0,44	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,78	low_impact	-3,78	medium_impact	0,1	medium_impact	0,42	0,63	0,8	74,71	11,6	N	0,29	N	0,85	polymorphism	1	0,1	.	.	.	.	.	.	COSM1155700	.	.	.	.	.	.	.	.
chrM	9294	9294	G	T	MI.6823	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	88	30	G	C	Ggc/Tgc	-11,9	0	0	probably_damaging	1	neutral	0,18	neutral	2,11	deleterious	-5,52	deleterious	-8	high_impact	3,83	damaging	0,54	damaging	0,02	deleterious	3,94	23,5	0,04	0,35	NA	NA	disease	0,87	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	-0,18	high_impact	2,25	0,28	0,8	74,71	11,6	N	0,31	N	0,98	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9294	9294	G	C	MI.6824	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	88	30	G	R	Ggc/Cgc	-11,9	0	0	probably_damaging	1	neutral	0,35	neutral	2,15	deleterious	-4,93	deleterious	-7,11	high_impact	4,38	neutral	0,62	damaging	0,02	deleterious	3,78	23,4	0,03	0,35	NA	NA	disease	0,87	disease	0,79	disease	0,81	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-3,78	medium_impact	0,04	high_impact	2,74	0,33	0,8	74,71	11,6	N	0,43	N	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9295	9295	G	C	MI.6825	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	89	30	G	A	gGc/gCc	6,14	1	0	probably_damaging	1	neutral	0,51	neutral	2,19	neutral	-2,59	deleterious	-5,33	medium_impact	3,23	damaging	0,46	damaging	0,01	deleterious	2,93	22	0,09	0,35	NA	NA	disease	0,59	disease	0,6	disease	0,56	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,78	low_impact	-3,78	medium_impact	0,2	medium_impact	1,71	0,38	0,8	74,71	11,6	N	0,47	N	0,3	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9295	9295	G	T	MI.6826	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	89	30	G	V	gGc/gTc	6,14	1	0	probably_damaging	1	neutral	0,52	neutral	2,13	deleterious	-4,19	deleterious	-7,99	high_impact	4,03	damaging	0,52	damaging	0,01	deleterious	3,59	23,2	0,03	0,35	NA	NA	disease	0,82	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	0,21	high_impact	2,43	0,19	0,8	74,71	11,6	N	0,49	N	0,97	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9295	9295	G	A	MI.6827	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	89	30	G	D	gGc/gAc	6,14	1	0	probably_damaging	1	neutral	0,21	neutral	2,18	deleterious	-5,01	deleterious	-6,22	high_impact	4,38	damaging	0,48	damaging	0,02	deleterious	3,62	23,2	0,03	0,35	NA	NA	disease	0,87	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,14	high_impact	2,74	0,16	0,8	74,71	11,6	P	0,59	P	0,98	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9297	9297	C	A	MI.6828	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	91	31	L	M	Cta/Ata	-10,75	0	0	probably_damaging	0,99	neutral	0,21	neutral	2,37	neutral	-1,94	neutral	-0,99	low_impact	1,38	neutral	0,74	neutral	0,77	deleterious	2,37	18,62	0,26	0,45	NA	NA	neutral	0,27	neutral	0,25	neutral	0,21	6	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,7	low_impact	-2,81	medium_impact	-0,14	medium_impact	0,05	0,59	0,8	76,25	10,27	N	0,49	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9297	9297	C	G	MI.6829	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	91	31	L	V	Cta/Gta	-10,75	0	0	probably_damaging	0,91	neutral	0,56	neutral	2,41	neutral	-0,65	neutral	-1,95	medium_impact	2,19	neutral	0,62	neutral	0,53	deleterious	3,23	22,8	0,22	0,45	NA	NA	disease	0,55	neutral	0,42	neutral	0,48	0	neutral	0,9	neutral	0,33	deleterious	1	deleterious	0,68	low_impact	-1,85	medium_impact	0,25	medium_impact	0,78	0,57	0,8	76,25	10,27	N	0,32	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8848	8848	T	A	MI.683	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	322	108	L	M	Tta/Ata	-10,51	0	0	probably_damaging	1	neutral	0,15	neutral	4,19	neutral	-2,43	neutral	-1,83	low_impact	1,48	neutral	0,85	neutral	0,74	deleterious	2,48	19,36	0,4	0,65	disease	0,72	neutral	0,48	neutral	0,36	disease	0,52	0	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	-0,13	medium_impact	0,17	0,73	0,9	47,79	8,45	N	0,41	N	0,96	disease_causing	0,53	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9298	9298	T	G	MI.6830	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	92	31	L	R	cTa/cGa	-1,49	0	0	probably_damaging	0,99	neutral	0,33	neutral	2,35	neutral	-2,44	deleterious	-4,54	medium_impact	3,5	damaging	0,59	neutral	0,29	deleterious	3,99	23,6	0,03	0,35	NA	NA	disease	0,89	disease	0,59	disease	0,74	5	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,85	low_impact	-2,81	medium_impact	0,02	medium_impact	1,95	0,24	0,8	76,25	10,27	N	0,33	N	0,98	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9298	9298	T	C	MI.6831	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	92	31	L	P	cTa/cCa	-1,49	0	0	probably_damaging	1	neutral	0,19	neutral	2,33	deleterious	-3,34	deleterious	-5,31	high_impact	3,85	damaging	0,52	neutral	0,34	deleterious	3,72	23,3	0,03	0,35	NA	NA	disease	0,85	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,17	high_impact	2,27	0,32	0,8	76,25	10,27	N	0,37	N	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9298	9298	T	A	MI.6832	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	92	31	L	Q	cTa/cAa	-1,49	0	0	probably_damaging	0,99	neutral	0,31	neutral	2,33	neutral	-2,45	deleterious	-4,42	high_impact	3,85	neutral	0,61	neutral	0,37	deleterious	3,88	23,5	0,05	0,35	NA	NA	disease	0,77	neutral	0,44	disease	0,59	2	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,77	low_impact	-2,81	medium_impact	-0,01	high_impact	2,27	0,3	0,8	76,25	10,27	N	0,41	N	0,79	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9300	9300	G	T	MI.6833	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	94	32	A	S	Gcc/Tcc	-1,03	0	0,02	benign	0,05	neutral	0,23	neutral	2,26	neutral	-0,94	neutral	-1,57	medium_impact	2,33	neutral	0,65	neutral	0,71	neutral	1,62	13,99	0,19	0,45	neutral	0,1	disease	0,52	disease	0,54	neutral	0,49	0	neutral	0,75	deleterious	0,59	neutral	-3	neutral	0,13	medium_impact	0,37	medium_impact	-0,11	medium_impact	0,91	0,54	0,8	17,62	14,59	N	0,43	N	0,13	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9300	9300	G	C	MI.6834	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	94	32	A	P	Gcc/Ccc	-1,03	0	0,02	benign	0,21	neutral	0,08	neutral	2,21	neutral	-2,59	deleterious	-2,62	medium_impact	3,19	damaging	0,55	neutral	0,32	deleterious	3,24	22,8	0,03	0,35	neutral	0,31	disease	0,85	disease	0,7	disease	0,79	6	neutral	0,91	neutral	0,44	neutral	-3	neutral	0,39	medium_impact	-0,31	medium_impact	-0,41	medium_impact	1,68	0,64	0,8	17,62	14,59	N	0,34	N	0,22	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9300	9300	G	A	MI.6835	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	94	32	A	T	Gcc/Acc	-1,03	0	0,02	benign	0	neutral	0,38	neutral	2,3	neutral	-0,29	neutral	-1,07	medium_impact	2	neutral	0,81	neutral	0,95	deleterious	0,84	9,73	0,15	0,4	neutral	0,12	neutral	0,43	neutral	0,34	neutral	0,44	1	neutral	0,62	deleterious	0,69	neutral	-3	neutral	0,11	high_impact	2,05	medium_impact	0,07	medium_impact	0,61	0,82	0,85	17,62	14,59	N	0,41	N	0	polymorphism	1	0,02	rs371745772	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9301	9301	C	T	MI.6836	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	95	32	A	V	gCc/gTc	-0,33	0	0	benign	0	neutral	0,37	neutral	2,58	neutral	1,71	neutral	0,5	neutral_impact	0,12	neutral	0,68	neutral	0,73	deleterious	0,4	6,65	0,14	0,4	neutral	0,09	neutral	0,2	neutral	0,27	neutral	0,33	3	neutral	0,63	deleterious	0,69	neutral	-6	neutral	0,08	high_impact	2,05	medium_impact	0,06	low_impact	-1,08	0,8	0,85	17,62	14,59	N	0,48	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9301	9301	C	G	MI.6837	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	95	32	A	G	gCc/gGc	-0,33	0	0	benign	0,07	neutral	0,45	neutral	2,24	neutral	-1,47	deleterious	-2,57	low_impact	1,42	neutral	0,64	neutral	0,62	deleterious	1,88	15,49	0,15	0,45	neutral	0,18	disease	0,58	neutral	0,46	neutral	0,47	1	neutral	0,5	deleterious	0,69	neutral	-6	neutral	0,17	medium_impact	0,22	medium_impact	0,14	medium_impact	0,09	0,61	0,8	17,62	14,59	N	0,36	N	0,27	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9301	9301	C	A	MI.6838	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	95	32	A	D	gCc/gAc	-0,33	0	0	benign	0,16	neutral	0,08	neutral	2,22	neutral	-2,39	deleterious	-3,11	high_impact	3,53	damaging	0,55	neutral	0,37	deleterious	2,76	21,1	0,02	0,35	neutral	0,22	disease	0,85	disease	0,69	disease	0,79	6	neutral	0,91	neutral	0,46	neutral	-2	neutral	0,28	medium_impact	-0,17	medium_impact	-0,41	medium_impact	1,98	0,49	0,8	17,62	14,59	N	0,38	N	0,25	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9303	9303	A	G	MI.6839	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	97	33	M	V	Atg/Gtg	-16,07	0	0	benign	0	neutral	0,56	neutral	2,35	neutral	0,24	neutral	-1,06	low_impact	0,92	neutral	0,67	damaging	0,28	neutral	-0,65	0,1	0,26	0,45	neutral	0,14	disease	0,58	neutral	0,44	neutral	0,43	1	neutral	0,44	deleterious	0,78	neutral	-6	neutral	0,13	high_impact	2,05	medium_impact	0,25	medium_impact	-0,36	0,48	0,8	76,25	10,49	N	0,27	N	0,96	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8848	8848	T	G	MI.684	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	322	108	L	V	Tta/Gta	-10,51	0	0	probably_damaging	0,99	deleterious	0,03	neutral	4,38	neutral	0,57	deleterious	-2,79	medium_impact	2,17	damaging	0,55	neutral	0,5	deleterious	3,4	23	0,35	0,65	neutral	0,31	disease	0,73	disease	0,6	disease	0,59	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,71	low_impact	-2,65	medium_impact	-0,56	medium_impact	0,76	0,56	0,9	47,79	8,45	N	0,37	N	0,87	disease_causing	0,59	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9303	9303	A	C	MI.6840	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	97	33	M	L	Atg/Ctg	-16,07	0	0	benign	0,01	neutral	1	neutral	2,51	neutral	1,36	neutral	-0,4	neutral_impact	-0,02	neutral	0,63	damaging	0,26	neutral	-0,26	0,82	0,23	0,45	neutral	0,12	disease	0,51	neutral	0,3	neutral	0,42	2	neutral	0,01	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,07	high_impact	1,9	low_impact	-1,2	0,4	0,8	76,25	10,49	N	0,27	N	0,95	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9303	9303	A	T	MI.6841	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	97	33	M	L	Atg/Ttg	-16,07	0	0	benign	0,01	neutral	1	neutral	2,51	neutral	1,36	neutral	-0,4	neutral_impact	-0,02	neutral	0,63	damaging	0,26	neutral	-0,2	1,1	0,23	0,45	neutral	0,12	disease	0,51	neutral	0,3	neutral	0,42	2	neutral	0,01	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,07	high_impact	1,9	low_impact	-1,2	0,4	0,8	76,25	10,49	N	0,27	N	0,95	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9304	9304	T	C	MI.6842	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	98	33	M	T	aTg/aCg	4,06	0,98	0	benign	0,1	neutral	0,26	neutral	2,27	neutral	-0,74	neutral	-1,62	low_impact	1,09	neutral	0,64	damaging	0,25	neutral	-0,19	1,14	0,13	0,4	neutral	0,14	disease	0,61	neutral	0,46	neutral	0,44	1	neutral	0,71	deleterious	0,58	neutral	-6	neutral	0,19	medium_impact	0,06	medium_impact	-0,07	medium_impact	-0,21	0,19	0,8	76,25	10,49	N	0,51	P	0,99	polymorphism	1	0,03	.	.	.	.	.	.	COSM1155702	.	.	.	.	.	.	.	.
chrM	9304	9304	T	A	MI.6843	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	98	33	M	K	aTg/aAg	4,06	0,98	0	benign	0,12	neutral	0,46	neutral	2,25	neutral	-1,07	neutral	-1,09	low_impact	0,82	neutral	0,62	damaging	0,14	deleterious	0,55	7,78	0,04	0,35	neutral	0,16	disease	0,62	neutral	0,44	neutral	0,43	1	neutral	0,46	deleterious	0,67	neutral	-6	neutral	0,23	medium_impact	-0,03	medium_impact	0,15	medium_impact	-0,45	0,3	0,8	76,25	10,49	N	0,45	N	0,99	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9305	9305	G	T	MI.6844	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	99	33	M	I	atG/atT	2,44	0,98	0	benign	0,01	neutral	0,52	neutral	2,33	neutral	0,09	neutral	-1,1	neutral_impact	0,6	neutral	0,68	neutral	0,34	deleterious	-0,04	2,26	0,21	0,45	neutral	0,15	disease	0,69	neutral	0,44	neutral	0,49	0	neutral	0,46	deleterious	0,76	neutral	-6	neutral	0,16	medium_impact	1,07	medium_impact	0,21	medium_impact	-0,65	0,52	0,8	76,25	10,49	N	0,42	N	0,95	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9305	9305	G	C	MI.6845	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	99	33	M	I	atG/atC	2,44	0,98	0	benign	0,01	neutral	0,52	neutral	2,33	neutral	0,09	neutral	-1,1	neutral_impact	0,6	neutral	0,68	neutral	0,34	neutral	-0,17	1,29	0,21	0,45	neutral	0,15	disease	0,69	neutral	0,44	neutral	0,49	0	neutral	0,46	deleterious	0,76	neutral	-6	neutral	0,16	medium_impact	1,07	medium_impact	0,21	medium_impact	-0,65	0,52	0,8	76,25	10,49	N	0,42	N	0,95	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9306	9306	T	C	MI.6846	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	100	34	W	R	Tga/Cga	-0,8	0,02	0	probably_damaging	1	neutral	0,42	neutral	2,48	neutral	-1,51	deleterious	-11,88	high_impact	4,08	neutral	0,69	damaging	0,03	deleterious	3,38	22,9	0,04	0,35	neutral	0,15	disease	0,87	disease	0,76	disease	0,76	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,75	low_impact	-3,78	medium_impact	0,11	high_impact	2,47	0,27	0,8	74,71	11,48	N	0,41	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9306	9306	T	G	MI.6847	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	100	34	W	G	Tga/Gga	-0,8	0,02	0	probably_damaging	1	neutral	0,3	neutral	2,46	neutral	-1,94	deleterious	-10,98	high_impact	3,53	neutral	0,63	damaging	0,04	deleterious	3,7	23,3	0,07	0,35	neutral	0,2	disease	0,75	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,71	low_impact	-3,78	medium_impact	-0,02	medium_impact	1,98	0,22	0,8	74,71	11,48	N	0,31	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9307	9307	G	C	MI.6848	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	101	34	W	S	tGa/tCa	7,53	1	0	probably_damaging	1	neutral	0,41	neutral	2,49	neutral	-1,33	deleterious	-11,84	medium_impact	2,69	neutral	0,62	damaging	0,03	deleterious	3,89	23,5	0,07	0,35	neutral	0,12	disease	0,75	disease	0,7	disease	0,55	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,7	low_impact	-3,78	medium_impact	0,1	medium_impact	1,23	0,24	0,8	74,71	11,48	N	0,37	N	0,97	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9307	9307	G	T	MI.6849	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	101	34	W	L	tGa/tTa	7,53	1	0	probably_damaging	1	neutral	0,75	neutral	2,6	neutral	0,1	deleterious	-10,94	medium_impact	2,26	damaging	0,58	damaging	0,04	deleterious	4,13	23,8	0,1	0,4	neutral	0,09	disease	0,73	disease	0,59	disease	0,52	0	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,7	low_impact	-3,78	medium_impact	0,46	medium_impact	0,84	0,18	0,8	74,71	11,48	N	0,35	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8849	8849	T	C	MI.685	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	323	108	L	S	tTa/tCa	-0,8	0	0	probably_damaging	1	deleterious	0,01	neutral	4,19	neutral	-0,66	deleterious	-5,58	medium_impact	2,81	neutral	0,65	neutral	0,55	deleterious	3,73	23,3	0,22	0,65	disease	0,58	disease	0,84	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-3,6	medium_impact	-0,84	medium_impact	1,31	0,66	0,9	47,79	8,45	N	0,29	N	0,98	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9308	9308	A	C	MI.6850	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	102	34	W	C	tgA/tgC	9,38	1	0	probably_damaging	1	neutral	0,21	neutral	2,44	deleterious	-3,22	deleterious	-11,03	high_impact	4,08	neutral	0,65	damaging	0,03	deleterious	3,86	23,5	0,06	0,35	neutral	0,33	disease	0,84	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,73	low_impact	-3,78	medium_impact	-0,14	high_impact	2,47	0,2	0,8	74,71	11,48	N	0,48	N	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9308	9308	A	T	MI.6851	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	102	34	W	C	tgA/tgT	9,38	1	0	probably_damaging	1	neutral	0,21	neutral	2,44	deleterious	-3,22	deleterious	-11,03	high_impact	4,08	neutral	0,65	damaging	0,03	deleterious	3,92	23,5	0,06	0,35	neutral	0,33	disease	0,84	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,73	low_impact	-3,78	medium_impact	-0,14	high_impact	2,47	0,2	0,8	74,71	11,48	N	0,49	N	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9309	9309	T	G	MI.6852	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	103	35	F	V	Ttt/Gtt	2,67	1	0	probably_damaging	1	neutral	0,51	neutral	2,24	neutral	-0,66	deleterious	-5,56	low_impact	1,66	neutral	0,7	neutral	0,56	deleterious	3,81	23,4	0,09	0,4	neutral	0,15	disease	0,84	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,26	neutral	-2	deleterious	0,69	low_impact	-3,78	medium_impact	0,2	medium_impact	0,31	0,34	0,8	73,95	11,58	N	0,38	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9309	9309	T	A	MI.6853	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	103	35	F	I	Ttt/Att	2,67	1	0	probably_damaging	0,99	neutral	0,37	neutral	2,3	neutral	-0,17	deleterious	-4,75	low_impact	1,52	neutral	0,61	neutral	0,82	deleterious	2,7	20,8	0,13	0,4	neutral	0,18	disease	0,85	neutral	0,48	disease	0,52	0	deleterious	0,99	neutral	0,19	neutral	-2	deleterious	0,71	low_impact	-2,81	medium_impact	0,06	medium_impact	0,18	0,5	0,8	73,95	11,58	N	0,44	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9309	9309	T	C	MI.6854	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	103	35	F	L	Ttt/Ctt	2,67	1	0	probably_damaging	0,98	neutral	0,59	neutral	2,53	neutral	1,05	deleterious	-4,67	low_impact	1,47	damaging	0,54	neutral	0,8	deleterious	2,09	16,8	0,18	0,45	neutral	0,14	disease	0,74	disease	0,58	disease	0,53	1	deleterious	0,98	neutral	0,31	neutral	-2	deleterious	0,68	low_impact	-2,51	medium_impact	0,28	medium_impact	0,14	0,69	0,85	73,95	11,58	N	0,42	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9310	9310	T	A	MI.6855	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	104	35	F	Y	tTt/tAt	4,52	1	0	probably_damaging	0,98	neutral	1	neutral	2,13	neutral	-2,86	neutral	-2,5	high_impact	3,5	neutral	0,8	neutral	0,44	deleterious	4,16	23,8	0,14	0,4	neutral	0,28	disease	0,76	disease	0,67	disease	0,69	4	deleterious	0,98	deleterious	0,51	deleterious	2	deleterious	0,71	low_impact	-2,51	high_impact	1,9	medium_impact	1,95	0,68	0,85	73,95	11,58	N	0,45	N	0,8	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9310	9310	T	C	MI.6856	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	104	35	F	S	tTt/tCt	4,52	1	0	probably_damaging	1	neutral	0,42	neutral	2,14	neutral	-2,73	deleterious	-6,51	high_impact	3,5	neutral	0,91	neutral	0,61	deleterious	4,13	23,8	0,04	0,35	neutral	0,1	disease	0,8	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,66	low_impact	-3,78	medium_impact	0,11	medium_impact	1,95	0,34	0,8	73,95	11,58	N	0,48	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9310	9310	T	G	MI.6857	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	104	35	F	C	tTt/tGt	4,52	1	0	probably_damaging	1	neutral	0,15	neutral	2,12	deleterious	-3,91	deleterious	-6,53	high_impact	3,5	neutral	0,76	neutral	0,47	deleterious	4,01	23,6	0,04	0,35	neutral	0,43	disease	0,86	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,73	low_impact	-3,78	medium_impact	-0,24	medium_impact	1,95	0,2	0,8	73,95	11,58	N	0,47	N	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9311	9311	T	G	MI.6858	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	105	35	F	L	ttT/ttG	7,53	1	0	probably_damaging	0,98	neutral	0,59	neutral	2,53	neutral	1,05	deleterious	-4,67	low_impact	1,47	damaging	0,54	neutral	0,8	deleterious	2,31	18,24	0,18	0,45	neutral	0,14	disease	0,74	disease	0,58	disease	0,53	1	deleterious	0,98	neutral	0,31	neutral	-2	deleterious	0,68	low_impact	-2,51	medium_impact	0,28	medium_impact	0,14	0,69	0,85	73,95	11,58	N	0,51	P	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9311	9311	T	A	MI.6859	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	105	35	F	L	ttT/ttA	7,53	1	0	probably_damaging	0,98	neutral	0,59	neutral	2,53	neutral	1,05	deleterious	-4,67	low_impact	1,47	damaging	0,54	neutral	0,8	deleterious	2,38	18,68	0,18	0,45	neutral	0,14	disease	0,74	disease	0,58	disease	0,53	1	deleterious	0,98	neutral	0,31	neutral	-2	deleterious	0,68	low_impact	-2,51	medium_impact	0,28	medium_impact	0,14	0,69	0,85	73,95	11,58	P	0,52	P	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8849	8849	T	G	MI.686	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	323	108	L	W	tTa/tGa	-0,8	0	0	probably_damaging	1	deleterious	0	neutral	4,12	deleterious	-4,85	deleterious	-5,52	medium_impact	3,15	neutral	0,74	neutral	0,49	deleterious	3,76	23,3	0,14	0,65	disease	0,92	disease	0,84	disease	0,62	disease	0,71	4	deleterious	1	neutral	0	deleterious	5	deleterious	0,83	low_impact	-3,6	low_impact	-1,4	medium_impact	1,6	0,58	0,9	47,79	8,45	N	0,29	N	1	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9312	9312	C	A	MI.6860	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	106	36	H	N	Cac/Aac	-4,96	0	0	probably_damaging	0,98	neutral	0,29	neutral	2,15	neutral	-1,87	deleterious	-5,89	low_impact	1,56	damaging	0,56	neutral	0,44	neutral	1,78	14,88	0,3	0,45	neutral	0,44	disease	0,6	disease	0,53	neutral	0,45	1	deleterious	0,98	neutral	0,16	neutral	-2	deleterious	0,72	low_impact	-2,51	medium_impact	-0,03	medium_impact	0,22	0,35	0,8	73,95	11,55	N	0,32	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9312	9312	C	T	MI.6861	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	106	36	H	Y	Cac/Tac	-4,96	0	0	probably_damaging	0,97	neutral	0,74	neutral	2,13	neutral	-2,49	deleterious	-5,16	medium_impact	2,8	neutral	0,63	damaging	0,27	deleterious	3,42	23	0,17	0,45	neutral	0,1	disease	0,72	disease	0,65	disease	0,52	0	neutral	0,96	neutral	0,39	deleterious	1	deleterious	0,7	low_impact	-2,34	medium_impact	0,45	medium_impact	1,33	0,15	0,8	73,95	11,55	N	0,21	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9312	9312	C	G	MI.6862	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	106	36	H	D	Cac/Gac	-4,96	0	0	probably_damaging	0,98	neutral	0,2	neutral	2,15	neutral	-1,95	deleterious	-7,63	high_impact	3,87	neutral	0,68	damaging	0,28	deleterious	3,35	22,9	0,05	0,35	disease	0,52	disease	0,78	disease	0,8	disease	0,77	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,75	low_impact	-2,51	medium_impact	-0,15	high_impact	2,29	0,34	0,8	73,95	11,55	N	0,42	N	0,98	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9313	9313	A	G	MI.6863	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	107	36	H	R	cAc/cGc	4,52	1	0	probably_damaging	0,97	neutral	0,24	neutral	2,21	neutral	-0,95	deleterious	-6,78	medium_impact	2,77	damaging	0,56	neutral	0,52	neutral	1,24	11,97	0,09	0,4	neutral	0,43	disease	0,8	disease	0,69	disease	0,57	1	neutral	0,98	neutral	0,14	deleterious	1	deleterious	0,78	low_impact	-2,34	medium_impact	-0,09	medium_impact	1,3	0,24	0,8	73,95	11,55	N	0,42	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9313	9313	A	C	MI.6864	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	107	36	H	P	cAc/cCc	4,52	1	0	probably_damaging	0,99	neutral	0,14	neutral	2,11	deleterious	-3,15	deleterious	-8,38	high_impact	3,87	damaging	0,59	neutral	0,32	deleterious	2,99	22,2	0,03	0,35	disease	0,57	disease	0,83	disease	0,82	disease	0,81	6	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,82	low_impact	-2,81	medium_impact	-0,26	high_impact	2,29	0,13	0,8	73,95	11,55	P	0,55	P	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9313	9313	A	T	MI.6865	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	107	36	H	L	cAc/cTc	4,52	1	0	probably_damaging	0,97	neutral	0,64	neutral	2,15	neutral	-2	deleterious	-9,4	medium_impact	2,93	neutral	0,66	neutral	0,34	deleterious	3,33	22,9	0,05	0,35	neutral	0,23	disease	0,83	disease	0,72	disease	0,74	5	neutral	0,96	neutral	0,34	deleterious	1	deleterious	0,73	low_impact	-2,34	medium_impact	0,33	medium_impact	1,44	0,07	0,8	73,95	11,55	N	0,42	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9314	9314	C	A	MI.6866	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	108	36	H	Q	caC/caA	6,84	1	0	probably_damaging	0,98	neutral	0,22	neutral	2,18	neutral	-1,34	deleterious	-6,67	medium_impact	2,58	damaging	0,58	neutral	0,35	deleterious	3,47	23	0,15	0,4	neutral	0,43	disease	0,68	disease	0,65	disease	0,61	2	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,74	low_impact	-2,51	medium_impact	-0,12	medium_impact	1,13	0,31	0,8	73,95	11,55	N	0,49	N	0,94	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9314	9314	C	G	MI.6867	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	108	36	H	Q	caC/caG	6,84	1	0	probably_damaging	0,98	neutral	0,22	neutral	2,18	neutral	-1,34	deleterious	-6,67	medium_impact	2,58	damaging	0,58	neutral	0,35	deleterious	3,19	22,7	0,15	0,4	neutral	0,43	disease	0,68	disease	0,65	disease	0,61	2	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,74	low_impact	-2,51	medium_impact	-0,12	medium_impact	1,13	0,31	0,8	73,95	11,55	N	0,48	N	0,94	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9315	9315	T	A	MI.6868	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	109	37	F	I	Ttc/Atc	-0,33	0,06	0	benign	0,01	neutral	0,38	neutral	2,59	neutral	0,07	neutral	-0,89	low_impact	1,69	neutral	0,71	neutral	0,57	neutral	1,31	12,34	0,11	0,4	neutral	0,15	disease	0,67	neutral	0,34	disease	0,52	0	neutral	0,61	deleterious	0,69	neutral	-6	neutral	0,16	medium_impact	1,07	medium_impact	0,07	medium_impact	0,33	0,42	0,8	70,88	10,44	N	0,4	N	0,69	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9315	9315	T	G	MI.6869	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	109	37	F	V	Ttc/Gtc	-0,33	0,06	0	benign	0,04	neutral	0,54	neutral	2,6	neutral	0,3	neutral	-0,57	low_impact	1,06	neutral	0,69	neutral	0,5	neutral	0,91	10,14	0,12	0,4	neutral	0,14	disease	0,65	neutral	0,34	disease	0,5	0	neutral	0,42	deleterious	0,75	neutral	-6	neutral	0,15	medium_impact	0,47	medium_impact	0,23	medium_impact	-0,23	0,3	0,8	70,88	10,44	N	0,3	N	0,79	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8850	8850	A	C	MI.687	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	324	108	L	F	ttA/ttC	5,91	0,9	0	probably_damaging	1	neutral	0,15	neutral	4,15	neutral	-2,56	deleterious	-3,57	low_impact	1,52	neutral	0,67	neutral	0,57	deleterious	2,47	19,25	0,39	0,65	disease	0,73	disease	0,67	neutral	0,42	neutral	0,4	2	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	-0,13	medium_impact	0,21	0,64	0,9	47,79	8,45	N	0,46	N	0,97	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9315	9315	T	C	MI.6870	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	109	37	F	L	Ttc/Ctc	-0,33	0,06	0	benign	0	neutral	0,65	neutral	2,67	neutral	0,98	neutral	-0,48	low_impact	0,88	neutral	0,77	neutral	0,72	deleterious	0,58	8	0,18	0,45	neutral	0,13	disease	0,51	neutral	0,32	neutral	0,41	2	neutral	0,35	deleterious	0,83	neutral	-6	neutral	0,13	high_impact	2,05	medium_impact	0,35	medium_impact	-0,39	0,44	0,8	70,88	10,44	N	0,27	N	0,7	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9316	9316	T	G	MI.6871	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	110	37	F	C	tTc/tGc	3,6	0,51	0	possibly_damaging	0,56	neutral	0,16	neutral	2,52	neutral	-2,03	neutral	-1,32	low_impact	1,69	neutral	0,67	neutral	0,54	deleterious	2,7	20,8	0,06	0,35	neutral	0,43	disease	0,77	neutral	0,25	disease	0,59	2	neutral	0,83	neutral	0,3	neutral	-3	deleterious	0,59	medium_impact	-0,97	medium_impact	-0,22	medium_impact	0,33	0,18	0,8	70,88	10,44	N	0,39	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9316	9316	T	C	MI.6872	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	110	37	F	S	tTc/tCc	3,6	0,51	0	benign	0,21	neutral	0,52	neutral	2,59	neutral	0,13	neutral	0,42	neutral_impact	-0,08	neutral	0,76	neutral	0,74	deleterious	0,86	9,82	0,06	0,35	neutral	0,15	disease	0,51	neutral	0,28	neutral	0,41	2	neutral	0,37	deleterious	0,66	neutral	-6	neutral	0,32	medium_impact	-0,31	medium_impact	0,21	low_impact	-1,25	0,16	0,8	70,88	10,44	N	0,31	N	0,93	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9316	9316	T	A	MI.6873	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	110	37	F	Y	tTc/tAc	3,6	0,51	0	benign	0,04	neutral	1	neutral	2,59	neutral	0,02	neutral	0,25	neutral_impact	0,19	neutral	0,79	neutral	0,94	deleterious	0,27	5,39	0,18	0,45	neutral	0,2	neutral	0,37	neutral	0,16	neutral	0,44	1	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,19	medium_impact	0,47	high_impact	1,9	low_impact	-1,01	0,51	0,8	70,88	10,44	N	0,33	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9317	9317	C	A	MI.6874	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	111	37	F	L	ttC/ttA	-0,1	0	0	benign	0	neutral	0,65	neutral	2,67	neutral	0,98	neutral	-0,48	low_impact	0,88	neutral	0,77	neutral	0,72	neutral	1,07	11,03	0,18	0,45	neutral	0,13	disease	0,51	neutral	0,32	neutral	0,41	2	neutral	0,35	deleterious	0,83	neutral	-6	neutral	0,13	high_impact	2,05	medium_impact	0,35	medium_impact	-0,39	0,44	0,8	70,88	10,44	N	0,28	N	0,7	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9317	9317	C	G	MI.6875	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	111	37	F	L	ttC/ttG	-0,1	0	0	benign	0	neutral	0,65	neutral	2,67	neutral	0,98	neutral	-0,48	low_impact	0,88	neutral	0,77	neutral	0,72	deleterious	0,78	9,35	0,18	0,45	neutral	0,13	disease	0,51	neutral	0,32	neutral	0,41	2	neutral	0,35	deleterious	0,83	neutral	-6	neutral	0,13	high_impact	2,05	medium_impact	0,35	medium_impact	-0,39	0,44	0,8	70,88	10,44	N	0,28	N	0,7	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9318	9318	C	A	MI.6876	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	112	38	H	N	Cac/Aac	-3,57	0	0	benign	0,26	neutral	0,4	neutral	2,35	neutral	0,94	neutral	-0,01	neutral_impact	-0,48	neutral	0,81	neutral	0,99	deleterious	0,67	8,64	0,32	0,5	neutral	0,08	neutral	0,2	neutral	0,34	neutral	0,34	3	neutral	0,52	deleterious	0,57	neutral	-6	neutral	0,26	medium_impact	-0,43	medium_impact	0,09	low_impact	-1,61	0,46	0,8	20,69	59,98	N	0,31	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9318	9318	C	T	MI.6877	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	112	38	H	Y	Cac/Tac	-3,57	0	0	benign	0	neutral	1	neutral	2,41	neutral	2	neutral	-1,02	neutral_impact	-0,32	neutral	0,81	neutral	0,91	neutral	-0,13	1,5	0,21	0,45	neutral	0,26	neutral	0,31	neutral	0,22	neutral	0,44	1	neutral	0	deleterious	1	neutral	-6	neutral	0,14	high_impact	2,05	high_impact	1,9	low_impact	-1,47	0,32	0,8	20,69	59,98	N	0,33	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9318	9318	C	G	MI.6878	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	112	38	H	D	Cac/Gac	-3,57	0	0	benign	0,26	neutral	0,2	neutral	2,34	neutral	0,52	neutral	-1,89	neutral_impact	0,78	neutral	0,71	neutral	0,65	deleterious	2,3	18,16	0,06	0,35	neutral	0,14	disease	0,6	disease	0,55	disease	0,63	3	neutral	0,76	deleterious	0,47	neutral	-6	neutral	0,29	medium_impact	-0,43	medium_impact	-0,15	medium_impact	-0,48	0,59	0,8	20,69	59,98	N	0,37	N	0,13	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9319	9319	A	G	MI.6879	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	113	38	H	R	cAc/cGc	0,13	0	0	benign	0,2	neutral	0,34	neutral	2,35	neutral	0,88	neutral	-1,61	low_impact	1,24	neutral	0,65	neutral	0,61	neutral	1,35	12,53	0,15	0,45	neutral	0,14	disease	0,63	neutral	0,44	disease	0,5	0	neutral	0,59	deleterious	0,57	neutral	-6	neutral	0,3	medium_impact	-0,28	medium_impact	0,03	medium_impact	-0,07	0,26	0,8	20,69	59,98	N	0,37	N	0,11	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8850	8850	A	T	MI.688	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	324	108	L	F	ttA/ttT	5,91	0,9	0	probably_damaging	1	neutral	0,15	neutral	4,15	neutral	-2,56	deleterious	-3,57	low_impact	1,52	neutral	0,67	neutral	0,57	deleterious	2,48	19,34	0,39	0,65	disease	0,73	disease	0,67	neutral	0,42	neutral	0,4	2	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	-0,13	medium_impact	0,21	0,64	0,9	47,79	8,45	P	0,47	N	0,97	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9319	9319	A	C	MI.6880	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	113	38	H	P	cAc/cCc	0,13	0	0	possibly_damaging	0,47	neutral	0,2	neutral	2,32	neutral	-0,19	deleterious	-2,72	low_impact	1,04	neutral	0,62	neutral	0,32	deleterious	2,88	21,8	0,07	0,35	neutral	0,28	disease	0,8	disease	0,52	disease	0,74	5	neutral	0,78	neutral	0,37	neutral	-3	deleterious	0,59	medium_impact	-0,82	medium_impact	-0,15	medium_impact	-0,25	0,29	0,8	20,69	59,98	N	0,29	N	0,51	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9319	9319	A	T	MI.6881	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	113	38	H	L	cAc/cTc	0,13	0	0	benign	0,08	neutral	0,65	neutral	2,41	neutral	1,93	deleterious	-2,68	neutral_impact	-0,19	neutral	0,75	neutral	0,62	deleterious	0,79	9,38	0,08	0,35	neutral	0,19	disease	0,6	neutral	0,44	neutral	0,4	2	neutral	0,26	deleterious	0,79	neutral	-6	neutral	0,18	medium_impact	0,16	medium_impact	0,35	low_impact	-1,35	0,18	0,8	20,69	59,98	N	0,28	N	0,33	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9320	9320	C	A	MI.6882	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	114	38	H	Q	caC/caA	2,67	0,02	0	benign	0,38	neutral	0,33	neutral	2,35	neutral	0,95	neutral	-1,52	neutral_impact	0,24	neutral	0,76	neutral	0,81	deleterious	2,22	17,65	0,2	0,45	neutral	0,13	neutral	0,34	neutral	0,35	neutral	0,43	1	neutral	0,61	deleterious	0,48	neutral	-6	neutral	0,29	medium_impact	-0,66	medium_impact	0,02	medium_impact	-0,97	0,41	0,8	20,69	59,98	N	0,4	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9320	9320	C	G	MI.6883	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	114	38	H	Q	caC/caG	2,67	0,02	0	benign	0,38	neutral	0,33	neutral	2,35	neutral	0,95	neutral	-1,52	neutral_impact	0,24	neutral	0,76	neutral	0,81	deleterious	2	16,21	0,2	0,45	neutral	0,13	neutral	0,34	neutral	0,35	neutral	0,43	1	neutral	0,61	deleterious	0,48	neutral	-6	neutral	0,29	medium_impact	-0,66	medium_impact	0,02	medium_impact	-0,97	0,41	0,8	20,69	59,98	N	0,4	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9321	9321	T	C	MI.6884	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	115	39	S	P	Tcc/Ccc	-2,42	0	0	benign	0,14	neutral	0,21	neutral	2,23	neutral	-2	deleterious	-2,54	low_impact	1,33	damaging	0,58	damaging	0,05	deleterious	1,95	15,88	0,07	0,35	neutral	0,33	disease	0,87	neutral	0,48	disease	0,7	4	neutral	0,76	deleterious	0,54	neutral	-6	neutral	0,38	medium_impact	-0,1	medium_impact	-0,14	medium_impact	0,01	0,17	0,8	19,92	26,44	N	0,28	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9321	9321	T	A	MI.6885	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	115	39	S	T	Tcc/Acc	-2,42	0	0	benign	0	neutral	0,4	neutral	2,27	neutral	-0,77	neutral	-0,58	neutral_impact	0,35	neutral	0,74	neutral	0,52	deleterious	0,47	7,18	0,2	0,45	neutral	0,17	neutral	0,38	neutral	0,31	neutral	0,45	1	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,14	high_impact	2,05	medium_impact	0,09	medium_impact	-0,87	0,41	0,8	19,92	26,44	N	0,42	N	0,63	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9321	9321	T	G	MI.6886	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	115	39	S	A	Tcc/Gcc	-2,42	0	0	benign	0,02	neutral	0,49	neutral	2,3	neutral	-0,23	neutral	-1,8	low_impact	0,84	neutral	0,66	damaging	0,21	neutral	1,69	14,34	0,27	0,45	neutral	0,14	neutral	0,49	neutral	0,47	neutral	0,45	1	neutral	0,49	deleterious	0,74	neutral	-6	neutral	0,15	medium_impact	0,77	medium_impact	0,18	medium_impact	-0,43	0,25	0,8	19,92	26,44	N	0,27	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9322	9322	C	T	MI.6887	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	116	39	S	F	tCc/tTc	1,05	0,01	0	possibly_damaging	0,56	neutral	0,73	neutral	2,21	deleterious	-3,16	deleterious	-3,33	low_impact	1,6	neutral	0,67	damaging	0,22	deleterious	2,18	17,35	0,07	0,35	neutral	0,36	disease	0,78	disease	0,55	disease	0,7	4	neutral	0,47	deleterious	0,59	neutral	-3	deleterious	0,59	medium_impact	-0,97	medium_impact	0,44	medium_impact	0,25	0,13	0,8	19,92	26,44	N	0,23	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9322	9322	C	G	MI.6888	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	116	39	S	C	tCc/tGc	1,05	0,01	0	benign	0,42	neutral	0,17	neutral	2,19	deleterious	-4,21	deleterious	-3,08	medium_impact	2,4	neutral	0,63	damaging	0,06	deleterious	3,07	22,4	0,1	0,4	disease	0,53	disease	0,78	disease	0,61	disease	0,74	5	neutral	0,8	neutral	0,38	neutral	-3	deleterious	0,55	medium_impact	-0,73	medium_impact	-0,2	medium_impact	0,97	0,23	0,8	19,92	26,44	N	0,27	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9322	9322	C	A	MI.6889	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	116	39	S	Y	tCc/tAc	1,05	0,01	0	possibly_damaging	0,56	neutral	1	neutral	2,21	neutral	-2,82	deleterious	-2,99	low_impact	1,5	neutral	0,64	damaging	0,14	deleterious	2,25	17,81	0,06	0,35	neutral	0,35	disease	0,8	disease	0,57	disease	0,71	4	neutral	0,56	deleterious	0,72	neutral	-3	deleterious	0,59	medium_impact	-0,97	high_impact	1,9	medium_impact	0,16	0,18	0,8	19,92	26,44	N	0,22	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8851	8851	T	C	MI.689	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	325	109	W	R	Tga/Cga	-6,58	0	0	probably_damaging	1	deleterious	0	neutral	4,18	deleterious	-3,07	deleterious	-12,91	high_impact	4,46	damaging	0,41	damaging	0,25	deleterious	3,56	23,1	0,28	0,65	disease	0,82	disease	0,96	disease	0,79	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	high_impact	2,72	0,24	0,9	49,12	8,75	P	0,69	P	0,97	disease_causing_automatic	0,98	0,43	rs199476136	Pathogenic|Pathogenic	Striatonigral_degeneration,_infantile,_mitochondrial|Leigh_syndrome	RCV000010280.6|RCV000144005.2	MedGen:OMIM|MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	T8851C	BSN	+	+	Reported	2
chrM	9324	9324	A	C	MI.6890	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	118	40	M	L	Ata/Cta	-11,67	0	0	benign	0	neutral	0,85	neutral	2,68	neutral	1,43	neutral	-0,64	neutral_impact	0,04	neutral	0,81	neutral	0,92	neutral	-0,25	0,84	0,24	0,45	neutral	0,12	neutral	0,44	neutral	0,47	neutral	0,43	1	neutral	0,15	deleterious	0,93	neutral	-6	neutral	0,12	high_impact	2,05	medium_impact	0,62	low_impact	-1,15	0,33	0,8	15,71	12,89	N	0,33	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9324	9324	A	T	MI.6891	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	118	40	M	L	Ata/Tta	-11,67	0	0	benign	0	neutral	0,85	neutral	2,68	neutral	1,43	neutral	-0,64	neutral_impact	0,04	neutral	0,81	neutral	0,92	neutral	-0,12	1,61	0,24	0,45	neutral	0,12	neutral	0,44	neutral	0,47	neutral	0,43	1	neutral	0,15	deleterious	0,93	neutral	-6	neutral	0,12	high_impact	2,05	medium_impact	0,62	low_impact	-1,15	0,33	0,8	15,71	12,89	N	0,33	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9324	9324	A	G	MI.6892	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	118	40	M	V	Ata/Gta	-11,67	0	0	benign	0	neutral	0,47	neutral	2,66	neutral	1,21	neutral	-0,61	neutral_impact	0,46	neutral	0,83	neutral	0,97	neutral	-0,55	0,16	0,21	0,45	neutral	0,13	neutral	0,45	disease	0,51	neutral	0,43	1	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	0,16	medium_impact	-0,77	0,39	0,8	15,71	12,89	N	0,28	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9325	9325	T	A	MI.6893	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	119	40	M	K	aTa/aAa	-4,73	0	0,01	benign	0	neutral	0,3	neutral	2,59	neutral	0,02	neutral	-1,41	low_impact	1,23	neutral	0,8	neutral	0,61	deleterious	0,74	9,09	0,05	0,35	neutral	0,19	disease	0,68	disease	0,65	disease	0,55	1	neutral	0,7	deleterious	0,65	neutral	-6	neutral	0,14	high_impact	2,05	medium_impact	-0,02	medium_impact	-0,08	0,28	0,8	15,71	12,89	N	0,31	N	0,24	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9325	9325	T	C	MI.6894	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	119	40	M	T	aTa/aCa	-4,73	0	0,01	benign	0	neutral	0,56	neutral	2,62	neutral	0,66	neutral	0,04	neutral_impact	0,06	neutral	0,8	neutral	0,99	neutral	-1,8	0	0,14	0,4	neutral	0,14	neutral	0,28	neutral	0,4	neutral	0,41	2	neutral	0,44	deleterious	0,78	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	0,25	low_impact	-1,13	0,17	0,8	15,71	12,89	N	0,27	N	0	polymorphism	1	0,01	rs879000531	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9326	9326	A	T	MI.6895	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	120	40	M	I	atA/atT	-8,2	0	0	benign	0	neutral	0,38	neutral	2,64	neutral	0,92	neutral	-0,76	neutral_impact	0,42	neutral	0,81	neutral	0,98	deleterious	0,01	2,64	0,2	0,45	neutral	0,14	neutral	0,48	neutral	0,33	neutral	0,41	2	neutral	0,62	deleterious	0,69	neutral	-6	neutral	0,12	high_impact	2,05	medium_impact	0,07	medium_impact	-0,81	0,42	0,8	15,71	12,89	N	0,33	N	0,02	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9326	9326	A	C	MI.6896	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	120	40	M	I	atA/atC	-8,2	0	0	benign	0	neutral	0,38	neutral	2,64	neutral	0,92	neutral	-0,76	neutral_impact	0,42	neutral	0,81	neutral	0,98	deleterious	-0,03	2,35	0,2	0,45	neutral	0,14	neutral	0,48	neutral	0,33	neutral	0,41	2	neutral	0,62	deleterious	0,69	neutral	-6	neutral	0,12	high_impact	2,05	medium_impact	0,07	medium_impact	-0,81	0,42	0,8	15,71	12,89	N	0,33	N	0,02	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9327	9327	A	C	MI.6897	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	121	41	T	P	Acg/Ccg	-13,06	0	0	benign	0,14	neutral	0,2	neutral	2,52	neutral	-1,32	neutral	-2,31	medium_impact	2,06	neutral	0,66	neutral	0,51	deleterious	1,83	15,18	0,06	0,35	neutral	0,22	disease	0,74	disease	0,58	disease	0,69	4	neutral	0,77	deleterious	0,53	neutral	-3	neutral	0,27	medium_impact	-0,1	medium_impact	-0,15	medium_impact	0,66	0,4	0,8	8,81	20,19	N	0,4	N	0,91	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9327	9327	A	T	MI.6898	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	121	41	T	S	Acg/Tcg	-13,06	0	0	benign	0,01	neutral	0,41	neutral	2,55	neutral	-0,56	neutral	-0,38	low_impact	0,86	neutral	0,8	neutral	0,85	neutral	-0,54	0,18	0,27	0,45	neutral	0,13	neutral	0,2	neutral	0,22	neutral	0,35	3	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,07	medium_impact	1,07	medium_impact	0,1	medium_impact	-0,41	0,6	0,8	8,81	20,19	N	0,41	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9327	9327	A	G	MI.6899	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	121	41	T	A	Acg/Gcg	-13,06	0	0	benign	0	neutral	0,36	neutral	2,57	neutral	-0,25	neutral	-1,23	low_impact	1,09	neutral	0,8	neutral	0,99	neutral	-0,08	1,86	0,2	0,45	neutral	0,11	neutral	0,29	neutral	0,39	neutral	0,42	2	neutral	0,64	deleterious	0,68	neutral	-6	neutral	0,08	high_impact	2,05	medium_impact	0,05	medium_impact	-0,21	0,38	0,8	8,81	20,19	N	0,38	N	0,16	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8556	8556	T	G	MI.69	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	30	10	I	M	atT/atG	-0,33	0	0	benign	0,04	neutral	0,29	neutral	4,68	neutral	-1,06	neutral	0,07	neutral_impact	0,21	neutral	0,9	neutral	0,93	deleterious	4,01	23,6	0,43	0,65	disease	0,6	neutral	0,09	neutral	0,18	neutral	0,36	3	neutral	0,69	deleterious	0,63	neutral	-6	neutral	0,19	medium_impact	0,55	medium_impact	0,07	medium_impact	-0,92	0,4	0,9	27,43	16,7	P	0,61	P	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8851	8851	T	G	MI.690	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	325	109	W	G	Tga/Gga	-6,58	0	0	probably_damaging	0,99	deleterious	0	neutral	4,15	neutral	-2,76	deleterious	-11,98	high_impact	4,46	neutral	0,62	neutral	0,42	deleterious	3,87	23,5	0,24	0,65	disease	0,83	disease	0,92	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-2,65	low_impact	-1,4	high_impact	2,72	0,28	0,9	49,12	8,75	N	0,5	N	1	disease_causing	0,99	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9328	9328	C	T	MI.6900	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	122	41	T	M	aCg/aTg	-4,27	0	0	benign	0,28	neutral	0,36	neutral	2,55	neutral	-0,63	neutral	-1,19	low_impact	0,88	neutral	0,75	neutral	0,68	deleterious	2,45	19,13	0,15	0,4	neutral	0,27	neutral	0,34	neutral	0,26	neutral	0,45	1	neutral	0,56	deleterious	0,54	neutral	-6	neutral	0,29	medium_impact	-0,47	medium_impact	0,05	medium_impact	-0,39	0,53	0,8	8,81	20,19	N	0,47	N	0,82	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9328	9328	C	A	MI.6901	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	122	41	T	K	aCg/aAg	-4,27	0	0	benign	0,03	neutral	0,2	neutral	2,53	neutral	-1,1	neutral	-1,62	low_impact	1,46	neutral	0,7	neutral	0,56	neutral	1,3	12,29	0,1	0,4	neutral	0,13	disease	0,63	disease	0,56	neutral	0,45	1	neutral	0,79	deleterious	0,59	neutral	-6	neutral	0,18	medium_impact	0,6	medium_impact	-0,15	medium_impact	0,13	0,43	0,8	8,81	20,19	N	0,37	N	0,86	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9330	9330	C	T	MI.6902	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	124	42	L	F	Ctc/Ttc	-8,66	0	0	probably_damaging	1	neutral	0,43	neutral	2,08	neutral	-1,97	deleterious	-2,95	medium_impact	2,04	damaging	0,59	damaging	0,11	deleterious	3,79	23,4	0,29	0,45	neutral	0,3	disease	0,58	disease	0,57	neutral	0,49	0	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,7	low_impact	-3,78	medium_impact	0,12	medium_impact	0,65	0,64	0,8	76,25	10,63	N	0,19	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9330	9330	C	A	MI.6903	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	124	42	L	I	Ctc/Atc	-8,66	0	0	probably_damaging	0,99	neutral	0,22	neutral	2,15	neutral	-1,15	neutral	-1,13	low_impact	1,08	neutral	0,67	neutral	0,41	deleterious	2,69	20,8	0,3	0,45	neutral	0,17	neutral	0,48	neutral	0,37	neutral	0,44	1	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,66	low_impact	-2,81	medium_impact	-0,12	medium_impact	-0,22	0,5	0,8	76,25	10,63	N	0,43	N	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9330	9330	C	G	MI.6904	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	124	42	L	V	Ctc/Gtc	-8,66	0	0	probably_damaging	0,98	neutral	0,21	neutral	2,16	neutral	-1,03	neutral	-1,71	low_impact	0,91	neutral	0,68	neutral	0,48	deleterious	2,23	17,68	0,31	0,45	neutral	0,21	neutral	0,41	neutral	0,4	neutral	0,44	1	deleterious	0,98	neutral	0,12	neutral	-2	deleterious	0,65	low_impact	-2,51	medium_impact	-0,14	medium_impact	-0,37	0,74	0,85	76,25	10,63	N	0,41	N	0,81	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9331	9331	T	C	MI.6905	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	125	42	L	P	cTc/cCc	-1,03	0	0	probably_damaging	1	neutral	0,07	neutral	2,01	deleterious	-4,01	deleterious	-5,04	medium_impact	2,52	neutral	0,61	damaging	0,05	deleterious	3,69	23,3	0,02	0,35	disease	0,62	disease	0,8	disease	0,75	disease	0,64	3	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,83	low_impact	-3,78	medium_impact	-0,45	medium_impact	1,08	0,34	0,8	76,25	10,63	N	0,24	N	0,99	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9331	9331	T	G	MI.6906	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	125	42	L	R	cTc/cGc	-1,03	0	0	probably_damaging	1	neutral	0,08	neutral	2,03	deleterious	-3,2	deleterious	-4,48	medium_impact	3,46	damaging	0,59	damaging	0,03	deleterious	4,04	23,7	0,02	0,35	disease	0,53	disease	0,89	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,85	low_impact	-3,78	medium_impact	-0,41	medium_impact	1,92	0,24	0,8	76,25	10,63	N	0,32	N	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9331	9331	T	A	MI.6907	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	125	42	L	H	cTc/cAc	-1,03	0	0	probably_damaging	1	neutral	0,13	neutral	2,01	deleterious	-3,94	deleterious	-5,21	medium_impact	3,46	neutral	0,61	damaging	0,05	deleterious	3,98	23,6	0,04	0,35	disease	0,62	disease	0,8	disease	0,73	disease	0,75	5	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,78	low_impact	-3,78	medium_impact	-0,28	medium_impact	1,92	0,18	0,8	76,25	10,63	N	0,27	N	0,97	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9333	9333	C	A	MI.6908	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	127	43	L	I	Ctc/Atc	-7,51	0	0	probably_damaging	0,98	neutral	0,3	neutral	1,95	neutral	-2	neutral	-0,95	medium_impact	2,02	neutral	0,68	neutral	0,78	deleterious	2,82	21,5	0,26	0,45	neutral	0,17	neutral	0,47	neutral	0,32	neutral	0,45	1	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,65	low_impact	-2,51	medium_impact	-0,02	medium_impact	0,63	0,46	0,8	78,16	10,28	N	0,45	N	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9333	9333	C	T	MI.6909	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	127	43	L	F	Ctc/Ttc	-7,51	0	0	probably_damaging	0,99	neutral	0,41	neutral	1,95	neutral	-2,07	neutral	-1,6	low_impact	0,9	neutral	0,75	neutral	0,75	deleterious	2,66	20,6	0,25	0,45	neutral	0,16	neutral	0,24	neutral	0,32	neutral	0,43	1	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,66	low_impact	-2,81	medium_impact	0,1	medium_impact	-0,38	0,59	0,8	78,16	10,28	N	0,33	N	0,95	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8852	8852	G	C	MI.691	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	326	109	W	S	tGa/tCa	7,53	1	0	probably_damaging	1	deleterious	0	neutral	4,23	neutral	-1,83	deleterious	-12,89	high_impact	4,46	damaging	0,59	neutral	0,44	deleterious	4	23,6	0,23	0,65	disease	0,55	disease	0,95	disease	0,73	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,6	low_impact	-1,4	high_impact	2,72	0,23	0,9	49,12	8,75	P	0,5	N	0,98	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9333	9333	C	G	MI.6910	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	127	43	L	V	Ctc/Gtc	-7,51	0	0	probably_damaging	0,96	neutral	0,28	neutral	1,98	neutral	-1,77	neutral	-1,57	low_impact	1,8	neutral	0,73	neutral	0,77	deleterious	3,23	22,8	0,26	0,45	neutral	0,14	neutral	0,39	neutral	0,33	neutral	0,44	1	neutral	0,96	neutral	0,16	neutral	-2	deleterious	0,63	low_impact	-2,21	medium_impact	-0,04	medium_impact	0,43	0,66	0,8	78,16	10,28	N	0,39	N	0,81	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9334	9334	T	C	MI.6911	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	128	43	L	P	cTc/cCc	-1,26	0	0	probably_damaging	1	neutral	0,06	neutral	1,82	deleterious	-5,18	deleterious	-4,74	medium_impact	2,9	damaging	0,57	neutral	0,33	deleterious	3,75	23,3	0,02	0,35	neutral	0,48	disease	0,84	disease	0,68	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,82	low_impact	-3,78	medium_impact	-0,49	medium_impact	1,42	0,4	0,8	78,16	10,28	N	0,28	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9334	9334	T	G	MI.6912	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	128	43	L	R	cTc/cGc	-1,26	0	0	probably_damaging	1	neutral	0,08	neutral	1,83	deleterious	-4,51	deleterious	-4,08	high_impact	3,88	damaging	0,56	neutral	0,35	deleterious	4,05	23,7	0,02	0,35	neutral	0,36	disease	0,87	disease	0,69	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	-0,41	high_impact	2,3	0,24	0,8	78,16	10,28	N	0,35	N	0,99	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9334	9334	T	A	MI.6913	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	128	43	L	H	cTc/cAc	-1,26	0	0	probably_damaging	1	neutral	0,13	neutral	1,82	deleterious	-5,13	deleterious	-4,42	high_impact	3,88	neutral	0,63	neutral	0,42	deleterious	3,99	23,6	0,04	0,35	neutral	0,46	disease	0,76	disease	0,65	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,75	low_impact	-3,78	medium_impact	-0,28	high_impact	2,3	0,26	0,8	78,16	10,28	N	0,41	N	0,97	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9336	9336	A	G	MI.6914	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	130	44	M	V	Ata/Gta	-4,5	0	0,01	benign	0	neutral	0,35	neutral	2,66	neutral	1,27	neutral	-0,32	neutral_impact	-0,86	neutral	0,83	neutral	0,93	neutral	-1,22	0,01	0,22	0,45	neutral	0,09	neutral	0,23	neutral	0,43	neutral	0,4	2	neutral	0,65	deleterious	0,68	neutral	-6	neutral	0,08	high_impact	2,05	medium_impact	0,04	low_impact	-1,95	0,35	0,8	14,18	14,3	N	0,31	N	0,3	polymorphism	1	0,01	rs28474779	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9336	9336	A	T	MI.6915	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	130	44	M	L	Ata/Tta	-4,5	0	0,01	benign	0	neutral	1	neutral	2,74	neutral	1,48	neutral	-0,15	neutral_impact	-1,4	neutral	0,8	neutral	0,94	neutral	-1,08	0,01	0,2	0,45	neutral	0,08	neutral	0,18	neutral	0,28	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,05	high_impact	1,9	low_impact	-2,44	0,28	0,8	14,18	14,3	N	0,37	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9336	9336	A	C	MI.6916	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	130	44	M	L	Ata/Cta	-4,5	0	0,01	benign	0	neutral	1	neutral	2,74	neutral	1,48	neutral	-0,15	neutral_impact	-1,4	neutral	0,8	neutral	0,94	neutral	-1,18	0,01	0,2	0,45	neutral	0,08	neutral	0,18	neutral	0,28	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,05	high_impact	1,9	low_impact	-2,44	0,28	0,8	14,18	14,3	N	0,36	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9337	9337	T	C	MI.6917	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	131	44	M	T	aTa/aCa	-7,04	0	0	benign	0	neutral	0,39	neutral	2,62	neutral	0,24	neutral	-0,46	neutral_impact	-0,42	neutral	0,82	neutral	0,99	neutral	-1,36	0	0,11	0,4	neutral	0,08	neutral	0,2	neutral	0,32	neutral	0,33	3	neutral	0,61	deleterious	0,7	neutral	-6	neutral	0,09	high_impact	2,05	medium_impact	0,08	low_impact	-1,56	0,2	0,8	14,18	14,3	N	0,33	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9337	9337	T	A	MI.6918	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	131	44	M	K	aTa/aAa	-7,04	0	0	benign	0	neutral	0,22	neutral	2,58	neutral	-1	neutral	-1,41	neutral_impact	0,38	neutral	0,77	neutral	0,68	deleterious	0,25	5,16	0,04	0,35	neutral	0,09	disease	0,51	disease	0,53	neutral	0,43	1	neutral	0,78	deleterious	0,61	neutral	-6	neutral	0,12	high_impact	2,05	medium_impact	-0,12	medium_impact	-0,84	0,29	0,8	14,18	14,3	N	0,35	N	0,44	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9338	9338	A	T	MI.6919	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	132	44	M	I	atA/atT	-4,27	0	0	benign	0	neutral	0,47	neutral	2,66	neutral	1,12	neutral	-0,4	neutral_impact	-0,81	neutral	0,81	neutral	0,91	neutral	-0,72	0,07	0,27	0,45	neutral	0,08	neutral	0,18	neutral	0,28	neutral	0,28	4	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,08	high_impact	2,05	medium_impact	0,16	low_impact	-1,91	0,34	0,8	14,18	14,3	N	0,34	N	0,17	disease_causing	1	0,01	rs386829075	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8852	8852	G	T	MI.692	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	326	109	W	L	tGa/tTa	7,53	1	0	probably_damaging	0,99	deleterious	0,04	neutral	4,25	neutral	-0,26	deleterious	-11,99	medium_impact	2,82	neutral	0,6	neutral	0,37	deleterious	4,21	23,9	0,22	0,65	neutral	0,38	disease	0,91	disease	0,72	disease	0,65	3	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,8	low_impact	-2,65	medium_impact	-0,49	medium_impact	1,32	0,26	0,9	49,12	8,75	N	0,45	N	1	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9338	9338	A	C	MI.6920	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	132	44	M	I	atA/atC	-4,27	0	0	benign	0	neutral	0,47	neutral	2,66	neutral	1,12	neutral	-0,4	neutral_impact	-0,81	neutral	0,81	neutral	0,91	neutral	-0,78	0,05	0,27	0,45	neutral	0,08	neutral	0,18	neutral	0,28	neutral	0,28	4	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,08	high_impact	2,05	medium_impact	0,16	low_impact	-1,91	0,34	0,8	14,18	14,3	N	0,33	N	0,17	disease_causing	1	0,01	rs386829075	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9339	9339	C	G	MI.6921	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	133	45	L	V	Cta/Gta	-11,9	0	0	benign	0,09	neutral	0,24	neutral	2,14	neutral	-1,13	neutral	-1,49	low_impact	1,29	neutral	0,7	neutral	0,47	neutral	1,25	12,02	0,28	0,45	neutral	0,16	neutral	0,36	neutral	0,34	neutral	0,44	1	neutral	0,73	deleterious	0,58	neutral	-6	neutral	0,15	medium_impact	0,11	medium_impact	-0,09	medium_impact	-0,03	0,62	0,8	20,69	31,76	N	0,45	N	0,08	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9339	9339	C	A	MI.6922	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	133	45	L	M	Cta/Ata	-11,9	0	0	possibly_damaging	0,62	neutral	0,18	neutral	2,07	neutral	-1,89	neutral	-1,02	medium_impact	1,95	neutral	0,72	neutral	0,73	deleterious	2,12	16,96	0,27	0,45	neutral	0,29	neutral	0,27	neutral	0,33	neutral	0,43	1	neutral	0,83	neutral	0,28	NA	0	neutral	0,41	low_impact	-1,08	medium_impact	-0,18	medium_impact	0,57	0,38	0,8	20,69	31,76	N	0,5	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9340	9340	T	G	MI.6923	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	134	45	L	R	cTa/cGa	-10,51	0	0	benign	0,38	neutral	0,13	neutral	2	deleterious	-3,57	deleterious	-4,62	high_impact	3,87	damaging	0,54	damaging	0,02	deleterious	3,72	23,3	0,02	0,35	disease	0,56	disease	0,84	disease	0,71	disease	0,78	6	neutral	0,85	neutral	0,38	neutral	-2	deleterious	0,46	medium_impact	-0,66	medium_impact	-0,28	high_impact	2,29	0,19	0,8	20,69	31,76	N	0,31	N	0,77	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9340	9340	T	A	MI.6924	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	134	45	L	Q	cTa/cAa	-10,51	0	0	possibly_damaging	0,54	neutral	0,11	neutral	2	deleterious	-3,63	deleterious	-4,5	high_impact	3,87	damaging	0,6	damaging	0,09	deleterious	4,02	23,6	0,03	0,35	disease	0,57	disease	0,72	disease	0,59	disease	0,69	4	neutral	0,88	neutral	0,29	deleterious	1	deleterious	0,49	medium_impact	-0,94	medium_impact	-0,33	high_impact	2,29	0,24	0,8	20,69	31,76	N	0,3	N	0,61	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9340	9340	T	C	MI.6925	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	134	45	L	P	cTa/cCa	-10,51	0	0	possibly_damaging	0,54	neutral	0,08	neutral	1,99	deleterious	-4,27	deleterious	-5,22	medium_impact	3,31	damaging	0,54	damaging	0,03	deleterious	3,54	23,1	0,02	0,35	disease	0,64	disease	0,78	disease	0,72	disease	0,74	5	neutral	0,91	neutral	0,27	NA	0	deleterious	0,56	medium_impact	-0,94	medium_impact	-0,41	medium_impact	1,78	0,33	0,8	20,69	31,76	N	0,27	N	0,84	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9342	9342	G	T	MI.6926	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	136	46	G	C	Ggc/Tgc	-2,42	0	0	probably_damaging	0,92	neutral	0,19	neutral	2,12	deleterious	-5,58	deleterious	-6,42	medium_impact	3,02	damaging	0,58	damaging	0,24	deleterious	3,96	23,6	0,06	0,35	disease	0,59	disease	0,83	disease	0,6	disease	0,67	3	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,74	low_impact	-1,9	medium_impact	-0,17	medium_impact	1,52	0,19	0,8	71,65	11,12	N	0,28	N	0,85	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9342	9342	G	A	MI.6927	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	136	46	G	S	Ggc/Agc	-2,42	0	0	benign	0,04	neutral	0,42	neutral	2,3	neutral	-2,39	deleterious	-3,77	low_impact	1,76	damaging	0,53	neutral	0,87	deleterious	2,16	17,27	0,11	0,4	neutral	0,16	disease	0,52	neutral	0,4	neutral	0,42	2	neutral	0,55	deleterious	0,69	neutral	-6	neutral	0,16	medium_impact	0,47	medium_impact	0,11	medium_impact	0,4	0,65	0,8	71,65	11,12	N	0,47	N	0,39	polymorphism	1	0,1	rs28672157	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9342	9342	G	C	MI.6928	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	136	46	G	R	Ggc/Cgc	-2,42	0	0	possibly_damaging	0,88	neutral	0,36	neutral	2,13	deleterious	-4,65	deleterious	-5,88	high_impact	4,34	neutral	0,65	damaging	0,2	deleterious	3,7	23,3	0,05	0,35	neutral	0,25	disease	0,87	disease	0,77	disease	0,75	5	neutral	0,89	neutral	0,24	deleterious	1	deleterious	0,74	low_impact	-1,71	medium_impact	0,05	high_impact	2,71	0,44	0,8	71,65	11,12	N	0,47	N	1	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9343	9343	G	C	MI.6929	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	137	46	G	A	gGc/gCc	5,22	1	0	benign	0,13	neutral	0,51	neutral	2,28	neutral	-2,45	deleterious	-3,71	medium_impact	2,17	damaging	0,59	neutral	0,55	neutral	1,32	12,39	0,16	0,45	neutral	0,14	neutral	0,45	neutral	0,41	neutral	0,39	2	neutral	0,4	deleterious	0,69	neutral	-3	neutral	0,29	medium_impact	-0,07	medium_impact	0,2	medium_impact	0,76	0,41	0,8	71,65	11,12	P	0,54	P	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8853	8853	A	C	MI.693	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	327	109	W	C	tgA/tgC	9,15	1	0	probably_damaging	1	deleterious	0	neutral	4,15	deleterious	-3,36	deleterious	-12,01	high_impact	4,12	damaging	0,53	damaging	0,24	deleterious	4	23,6	0,27	0,65	disease	0,86	disease	0,94	disease	0,75	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,43	0,27	0,9	49,12	8,75	N	0,49	N	1	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9343	9343	G	A	MI.6930	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	137	46	G	D	gGc/gAc	5,22	1	0	possibly_damaging	0,59	neutral	0,2	neutral	2,12	deleterious	-4,68	deleterious	-5,17	high_impact	4,34	neutral	0,64	damaging	0,23	deleterious	3,71	23,3	0,06	0,35	neutral	0,24	disease	0,83	disease	0,76	disease	0,75	5	neutral	0,8	neutral	0,31	deleterious	1	deleterious	0,62	low_impact	-1,02	medium_impact	-0,15	high_impact	2,71	0,26	0,8	71,65	11,12	P	0,56	P	0,95	polymorphism	1	0,23	.	.	.	.	.	.	COSM1138424	.	.	.	.	.	.	.	.
chrM	9343	9343	G	T	MI.6931	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	137	46	G	V	gGc/gTc	5,22	1	0	possibly_damaging	0,84	neutral	0,54	neutral	2,14	deleterious	-4,06	deleterious	-6,44	high_impact	3,65	damaging	0,57	neutral	0,29	deleterious	3,57	23,1	0,07	0,35	neutral	0,29	disease	0,78	disease	0,67	disease	0,69	4	neutral	0,82	neutral	0,35	deleterious	1	deleterious	0,68	low_impact	-1,57	medium_impact	0,23	high_impact	2,09	0,19	0,8	71,65	11,12	N	0,47	N	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9345	9345	C	A	MI.6932	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	139	47	L	M	Cta/Ata	-9,13	0	0	benign	0,01	neutral	0,37	neutral	1,99	neutral	-2,38	neutral	-0,53	medium_impact	2,21	neutral	0,69	neutral	0,43	deleterious	0,45	7,02	0,27	0,45	neutral	0,22	neutral	0,29	neutral	0,26	neutral	0,44	1	neutral	0,62	deleterious	0,68	neutral	-3	neutral	0,13	medium_impact	1,07	medium_impact	0,06	medium_impact	0,8	0,5	0,8	64,75	11,98	N	0,51	P	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9345	9345	C	G	MI.6933	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	139	47	L	V	Cta/Gta	-9,13	0	0	benign	0,01	neutral	0,48	neutral	2,07	neutral	-1,45	neutral	-1,31	low_impact	1,69	neutral	0,72	damaging	0,27	deleterious	0,31	5,81	0,25	0,45	neutral	0,16	neutral	0,31	neutral	0,26	neutral	0,45	1	neutral	0,5	deleterious	0,74	neutral	-6	neutral	0,13	medium_impact	1,07	medium_impact	0,17	medium_impact	0,33	0,51	0,8	64,75	11,98	N	0,36	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9346	9346	T	A	MI.6934	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	140	47	L	Q	cTa/cAa	-2,88	0	0	benign	0,32	neutral	0,22	neutral	1,93	deleterious	-3,96	deleterious	-3,56	high_impact	3,56	neutral	0,67	damaging	0,1	deleterious	3,74	23,3	0,06	0,35	neutral	0,28	disease	0,7	disease	0,51	disease	0,55	1	neutral	0,74	neutral	0,45	neutral	-2	deleterious	0,44	medium_impact	-0,55	medium_impact	-0,12	high_impact	2,01	0,23	0,8	64,75	11,98	N	0,34	N	0,87	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9346	9346	T	C	MI.6935	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	140	47	L	P	cTa/cCa	-2,88	0	0	possibly_damaging	0,68	neutral	0,15	neutral	1,91	deleterious	-4,65	deleterious	-4,44	high_impact	3,56	damaging	0,55	damaging	0,06	deleterious	3,69	23,3	0,04	0,35	neutral	0,29	disease	0,81	disease	0,66	disease	0,74	5	neutral	0,87	neutral	0,24	deleterious	1	deleterious	0,69	low_impact	-1,19	medium_impact	-0,24	high_impact	2,01	0,32	0,8	64,75	11,98	N	0,27	N	0,93	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9346	9346	T	G	MI.6936	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	140	47	L	R	cTa/cGa	-2,88	0	0	benign	0,32	neutral	0,26	neutral	1,93	deleterious	-3,92	deleterious	-3,82	high_impact	3,92	damaging	0,56	damaging	0,06	deleterious	3,89	23,5	0,04	0,35	neutral	0,28	disease	0,84	disease	0,65	disease	0,75	5	neutral	0,69	deleterious	0,47	neutral	-2	deleterious	0,51	medium_impact	-0,55	medium_impact	-0,07	high_impact	2,33	0,21	0,8	64,75	11,98	N	0,34	N	0,97	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9348	9348	C	A	MI.6937	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	142	48	L	M	Cta/Ata	-2,65	0	0	possibly_damaging	0,49	neutral	0,28	neutral	2,15	neutral	-2,02	neutral	-0,7	low_impact	1,48	neutral	0,76	neutral	0,92	deleterious	2,23	17,71	0,25	0,45	neutral	0,25	neutral	0,24	neutral	0,28	neutral	0,44	1	neutral	0,69	neutral	0,4	neutral	-3	neutral	0,34	medium_impact	-0,85	medium_impact	-0,04	medium_impact	0,14	0,52	0,8	16,86	19,7	N	0,48	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9348	9348	C	G	MI.6938	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	142	48	L	V	Cta/Gta	-2,65	0	0	benign	0	neutral	0,57	neutral	2,32	neutral	-0,04	neutral	-0,38	neutral_impact	0,55	neutral	0,77	neutral	0,93	neutral	-0,37	0,45	0,21	0,45	neutral	0,13	neutral	0,18	neutral	0,28	neutral	0,29	4	neutral	0,42	deleterious	0,79	neutral	-6	neutral	0,09	high_impact	2,05	medium_impact	0,26	medium_impact	-0,69	0,41	0,8	16,86	19,7	N	0,32	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9349	9349	T	A	MI.6939	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	143	48	L	Q	cTa/cAa	-7,97	0	0	benign	0,41	neutral	0,16	neutral	2,12	neutral	-2,92	deleterious	-3,62	medium_impact	3,41	neutral	0,7	damaging	0,16	deleterious	3,92	23,5	0,06	0,35	neutral	0,36	disease	0,56	disease	0,51	disease	0,53	1	neutral	0,81	neutral	0,38	neutral	-3	neutral	0,37	medium_impact	-0,72	medium_impact	-0,22	medium_impact	1,87	0,27	0,8	16,86	19,7	N	0,36	N	0,73	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8853	8853	A	T	MI.694	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	327	109	W	C	tgA/tgT	9,15	1	0	probably_damaging	1	deleterious	0	neutral	4,15	deleterious	-3,36	deleterious	-12,01	high_impact	4,12	damaging	0,53	damaging	0,24	deleterious	4,08	23,7	0,27	0,65	disease	0,86	disease	0,94	disease	0,75	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,43	0,27	0,9	49,12	8,75	N	0,49	N	1	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9349	9349	T	C	MI.6940	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	143	48	L	P	cTa/cCa	-7,97	0	0	benign	0,3	neutral	0,11	neutral	2,11	deleterious	-3,57	deleterious	-4,11	medium_impact	2,61	damaging	0,59	damaging	0,12	deleterious	3,59	23,2	0,04	0,35	neutral	0,45	disease	0,78	disease	0,66	disease	0,71	4	neutral	0,87	neutral	0,41	neutral	-3	deleterious	0,51	medium_impact	-0,51	medium_impact	-0,33	medium_impact	1,16	0,37	0,8	16,86	19,7	N	0,27	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9349	9349	T	G	MI.6941	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	143	48	L	R	cTa/cGa	-7,97	0	0	benign	0,34	neutral	0,19	neutral	2,12	neutral	-2,85	deleterious	-3,8	medium_impact	3,41	damaging	0,6	damaging	0,11	deleterious	3,86	23,5	0,04	0,35	neutral	0,34	disease	0,79	disease	0,64	disease	0,74	5	neutral	0,77	neutral	0,43	neutral	-3	neutral	0,42	medium_impact	-0,59	medium_impact	-0,17	medium_impact	1,87	0,21	0,8	16,86	19,7	N	0,3	N	0,88	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9351	9351	A	T	MI.6942	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	145	49	T	S	Acc/Tcc	-3,57	0	0	probably_damaging	0,95	neutral	0,26	neutral	2,58	neutral	-0,37	neutral	-1	neutral_impact	-0,03	neutral	0,71	neutral	0,46	deleterious	1,88	15,45	0,35	0,5	neutral	0,1	neutral	0,2	neutral	0,23	neutral	0,35	3	neutral	0,96	neutral	0,16	neutral	-2	deleterious	0,62	low_impact	-2,11	medium_impact	-0,07	low_impact	-1,21	0,55	0,8	21,46	32,35	N	0,4	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9351	9351	A	G	MI.6943	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	145	49	T	A	Acc/Gcc	-3,57	0	0	probably_damaging	0,95	neutral	0,24	neutral	2,59	neutral	0,18	neutral	-0,31	neutral_impact	0,5	neutral	0,66	neutral	0,36	deleterious	2,01	16,3	0,24	0,45	neutral	0,14	neutral	0,27	neutral	0,35	neutral	0,42	2	neutral	0,97	neutral	0,15	neutral	-2	deleterious	0,62	low_impact	-2,11	medium_impact	-0,09	medium_impact	-0,73	0,31	0,8	21,46	32,35	N	0,38	N	0,56	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9351	9351	A	C	MI.6944	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	145	49	T	P	Acc/Ccc	-3,57	0	0	probably_damaging	0,99	neutral	0,05	neutral	2,51	neutral	-2,33	neutral	-2,14	medium_impact	2,1	damaging	0,57	damaging	0,06	deleterious	3,32	22,9	0,06	0,35	neutral	0,35	disease	0,77	disease	0,61	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,75	low_impact	-2,81	medium_impact	-0,54	medium_impact	0,7	0,33	0,8	21,46	32,35	N	0,23	N	0,93	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9352	9352	C	T	MI.6945	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	146	49	T	I	aCc/aTc	0,36	0	0	probably_damaging	1	neutral	0,65	neutral	2,62	neutral	0,63	neutral	1,6	neutral_impact	-0,1	neutral	0,68	neutral	0,45	neutral	1,68	14,32	0,11	0,4	neutral	0,1	neutral	0,22	neutral	0,22	neutral	0,36	3	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,64	low_impact	-3,78	medium_impact	0,35	low_impact	-1,27	0,48	0,8	21,46	32,35	N	0,29	N	0,83	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9352	9352	C	A	MI.6946	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	146	49	T	N	aCc/aAc	0,36	0	0	probably_damaging	0,99	neutral	0,14	neutral	2,52	neutral	-1,76	neutral	-2,08	low_impact	1,25	neutral	0,72	damaging	0,12	deleterious	3,59	23,2	0,26	0,45	neutral	0,19	disease	0,52	neutral	0,37	neutral	0,48	0	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,67	low_impact	-2,81	medium_impact	-0,26	medium_impact	-0,06	0,62	0,8	21,46	32,35	N	0,3	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9352	9352	C	G	MI.6947	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	146	49	T	S	aCc/aGc	0,36	0	0	probably_damaging	0,95	neutral	0,26	neutral	2,58	neutral	-0,37	neutral	-1	neutral_impact	-0,03	neutral	0,71	neutral	0,46	deleterious	2,06	16,61	0,35	0,5	neutral	0,1	neutral	0,2	neutral	0,23	neutral	0,35	3	neutral	0,96	neutral	0,16	neutral	-2	deleterious	0,62	low_impact	-2,11	medium_impact	-0,07	low_impact	-1,21	0,55	0,8	21,46	32,35	N	0,42	N	0,23	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9354	9354	A	C	MI.6948	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	148	50	N	H	Aac/Cac	-11,67	0	0	possibly_damaging	0,61	deleterious	0,04	neutral	2,58	neutral	-0,49	neutral	-0,9	low_impact	1,45	neutral	0,72	neutral	0,47	deleterious	2,8	21,4	0,25	0,45	neutral	0,29	neutral	0,24	disease	0,56	neutral	0,46	1	neutral	0,96	neutral	0,22	deleterious	1	deleterious	0,55	low_impact	-1,06	medium_impact	-0,6	medium_impact	0,12	0,33	0,8	24,9	36,4	N	0,48	N	0,7	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9354	9354	A	T	MI.6949	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	148	50	N	Y	Aac/Tac	-11,67	0	0	possibly_damaging	0,65	neutral	0,07	neutral	2,6	neutral	0,44	neutral	-0,15	low_impact	1,09	neutral	0,69	neutral	0,49	deleterious	3,47	23	0,12	0,4	neutral	0,28	neutral	0,33	neutral	0,49	neutral	0,45	1	neutral	0,93	neutral	0,21	neutral	-3	deleterious	0,58	low_impact	-1,13	medium_impact	-0,45	medium_impact	-0,21	0,33	0,8	24,9	36,4	N	0,48	N	0,96	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8854	8854	G	C	MI.695	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	328	110	A	P	Gcg/Ccg	1,29	0,99	0,01	possibly_damaging	0,55	deleterious	0	neutral	4,29	deleterious	-3,16	deleterious	-3,28	low_impact	1,7	neutral	0,71	neutral	0,34	deleterious	3,46	23	0,14	0,65	disease	0,84	disease	0,91	disease	0,62	disease	0,75	5	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,76	medium_impact	-0,84	low_impact	-1,4	medium_impact	0,36	0,84	0,9	22,12	15,91	N	0,32	N	0,97	disease_causing	0,64	0,1	rs386829055	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9354	9354	A	G	MI.6950	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	148	50	N	D	Aac/Gac	-11,67	0	0	benign	0,06	deleterious	0,01	neutral	2,58	neutral	-0,93	neutral	-0,9	low_impact	1,45	neutral	0,66	neutral	0,51	deleterious	1,93	15,76	0,38	0,5	neutral	0,15	neutral	0,27	disease	0,55	neutral	0,45	1	deleterious	0,99	deleterious	0,48	neutral	-2	neutral	0,19	medium_impact	0,29	medium_impact	-0,95	medium_impact	0,12	0,43	0,8	24,9	36,4	N	0,45	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9355	9355	A	G	MI.6951	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	149	50	N	S	aAc/aGc	2,44	0,01	0,01	benign	0	deleterious	0,04	neutral	2,61	neutral	1,07	neutral	0,49	neutral_impact	0,34	neutral	0,74	neutral	0,78	deleterious	-0,02	2,38	0,37	0,5	neutral	0,14	neutral	0,15	neutral	0,28	neutral	0,3	4	neutral	0,96	deleterious	0,52	neutral	-2	neutral	0,1	high_impact	2,05	medium_impact	-0,6	medium_impact	-0,88	0,35	0,8	24,9	36,4	P	0,54	P	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9355	9355	A	T	MI.6952	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	149	50	N	I	aAc/aTc	2,44	0,01	0,01	benign	0,2	neutral	1	neutral	2,73	neutral	2,53	neutral	2,07	neutral_impact	-1,86	neutral	0,77	neutral	0,78	neutral	1,8	14,97	0,13	0,4	neutral	0,11	neutral	0,2	neutral	0,2	neutral	0,34	3	neutral	0,2	deleterious	0,9	neutral	-6	neutral	0,31	medium_impact	-0,28	high_impact	1,9	low_impact	-2,85	0,27	0,8	24,9	36,4	N	0,37	N	0,98	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9355	9355	A	C	MI.6953	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	149	50	N	T	aAc/aCc	2,44	0,01	0,01	benign	0	neutral	0,4	neutral	2,67	neutral	1,47	neutral	1,97	neutral_impact	-1,44	neutral	0,72	neutral	0,79	neutral	-0,97	0,02	0,21	0,45	neutral	0,14	neutral	0,08	neutral	0,2	neutral	0,28	4	neutral	0,6	deleterious	0,7	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	0,09	low_impact	-2,47	0,41	0,8	24,9	36,4	N	0,51	P	0,73	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9356	9356	C	A	MI.6954	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	150	50	N	K	aaC/aaA	0,36	0	0	benign	0,13	deleterious	0,02	neutral	2,6	neutral	0,21	neutral	-0,35	low_impact	1,45	neutral	0,67	neutral	0,44	deleterious	2,55	19,79	0,25	0,45	neutral	0,14	neutral	0,31	disease	0,55	neutral	0,46	1	neutral	0,98	neutral	0,45	neutral	-2	neutral	0,33	medium_impact	-0,07	medium_impact	-0,77	medium_impact	0,12	0,44	0,8	24,9	36,4	N	0,45	N	0,97	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9356	9356	C	G	MI.6955	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	150	50	N	K	aaC/aaG	0,36	0	0	benign	0,13	deleterious	0,02	neutral	2,6	neutral	0,21	neutral	-0,35	low_impact	1,45	neutral	0,67	neutral	0,44	deleterious	2,11	16,89	0,25	0,45	neutral	0,14	neutral	0,31	disease	0,55	neutral	0,46	1	neutral	0,98	neutral	0,45	neutral	-2	neutral	0,33	medium_impact	-0,07	medium_impact	-0,77	medium_impact	0,12	0,44	0,8	24,9	36,4	N	0,45	N	0,97	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9357	9357	A	G	MI.6956	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	151	51	T	A	Aca/Gca	-8,89	0	0	benign	0	neutral	0,26	neutral	2,34	neutral	0,35	neutral	-0,24	neutral_impact	-0,48	neutral	0,7	neutral	0,89	deleterious	0,11	3,67	0,21	0,45	neutral	0,09	neutral	0,3	neutral	0,38	neutral	0,41	2	neutral	0,74	deleterious	0,63	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	-0,07	low_impact	-1,61	0,44	0,8	20,69	20,98	N	0,41	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9357	9357	A	C	MI.6957	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	151	51	T	P	Aca/Cca	-8,89	0	0	benign	0,15	neutral	0,05	neutral	2,27	neutral	-1,88	neutral	-2,04	low_impact	1,04	damaging	0,58	damaging	0,14	neutral	1,55	13,56	0,07	0,35	neutral	0,34	disease	0,78	disease	0,53	disease	0,75	5	neutral	0,94	neutral	0,45	neutral	-6	neutral	0,26	medium_impact	-0,14	medium_impact	-0,54	medium_impact	-0,25	0,36	0,8	20,69	20,98	N	0,29	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9357	9357	A	T	MI.6958	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	151	51	T	S	Aca/Tca	-8,89	0	0	benign	0,03	neutral	0,53	neutral	2,32	neutral	-0,07	neutral	-0,92	neutral_impact	0,32	neutral	0,68	neutral	0,49	deleterious	-0,06	2,07	0,34	0,5	neutral	0,16	neutral	0,26	neutral	0,27	neutral	0,44	1	neutral	0,43	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	0,6	medium_impact	0,22	medium_impact	-0,9	0,57	0,8	20,69	20,98	N	0,35	N	0,19	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9358	9358	C	A	MI.6959	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	152	51	T	K	aCa/aAa	-4,5	0	0	benign	0,05	neutral	0,07	neutral	2,29	neutral	-0,95	neutral	-1,61	low_impact	1,73	neutral	0,63	damaging	0,16	deleterious	2,42	18,92	0,07	0,35	neutral	0,19	disease	0,61	disease	0,61	disease	0,72	4	neutral	0,93	deleterious	0,51	neutral	-6	neutral	0,17	medium_impact	0,37	medium_impact	-0,45	medium_impact	0,37	0,55	0,8	20,69	20,98	N	0,35	N	0,57	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8854	8854	G	A	MI.696	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	328	110	A	T	Gcg/Acg	1,29	0,99	0,01	benign	0,01	deleterious	0,04	neutral	4,36	neutral	-0,89	neutral	-1,75	neutral_impact	0,55	neutral	0,96	neutral	0,83	deleterious	2,13	17,05	0,46	0,65	disease	0,51	disease	0,59	neutral	0,28	neutral	0,41	2	neutral	0,96	deleterious	0,52	neutral	-2	neutral	0,22	medium_impact	1,14	medium_impact	-0,49	medium_impact	-0,63	0,7	0,9	22,12	15,91	N	0,47	N	0,8	polymorphism	0,66	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9358	9358	C	T	MI.6960	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	152	51	T	M	aCa/aTa	-4,5	0	0	benign	0	neutral	0,25	neutral	2,33	neutral	0,25	neutral	1,34	neutral_impact	-0,2	neutral	0,71	neutral	0,98	deleterious	0,6	8,18	0,12	0,4	neutral	0,19	neutral	0,33	neutral	0,28	neutral	0,45	1	neutral	0,75	deleterious	0,63	neutral	-6	neutral	0,11	high_impact	2,05	medium_impact	-0,08	low_impact	-1,36	0,56	0,8	20,69	20,98	N	0,46	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9360	9360	C	G	MI.6961	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	154	52	L	V	Cta/Gta	-9,59	0	0	benign	0,1	neutral	0,45	neutral	2,42	neutral	-0,2	neutral	-1,69	medium_impact	2,17	neutral	0,6	damaging	0,07	neutral	1,69	14,36	0,23	0,45	neutral	0,15	neutral	0,44	neutral	0,36	neutral	0,44	1	neutral	0,48	deleterious	0,68	neutral	-3	neutral	0,18	medium_impact	0,06	medium_impact	0,14	medium_impact	0,76	0,55	0,8	20,31	27,93	N	0,28	N	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9360	9360	C	A	MI.6962	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	154	52	L	M	Cta/Ata	-9,59	0	0	benign	0,1	neutral	0,32	neutral	2,36	neutral	-1,76	neutral	-0,87	low_impact	1,84	neutral	0,66	damaging	0,26	neutral	0,93	10,24	0,24	0,45	neutral	0,27	neutral	0,37	neutral	0,34	neutral	0,44	1	neutral	0,64	deleterious	0,61	neutral	-6	neutral	0,19	medium_impact	0,06	medium_impact	0,01	medium_impact	0,47	0,41	0,8	20,31	27,93	N	0,4	N	0,85	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9361	9361	T	G	MI.6963	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	155	52	L	R	cTa/cGa	-1,26	0	0	possibly_damaging	0,78	neutral	0,05	neutral	2,35	neutral	-2,5	deleterious	-4,66	high_impact	3,87	neutral	0,6	damaging	0,02	deleterious	3,99	23,6	0,02	0,35	neutral	0,36	disease	0,88	disease	0,68	disease	0,75	5	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,72	low_impact	-1,4	medium_impact	-0,54	high_impact	2,29	0,24	0,8	20,31	27,93	N	0,34	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9361	9361	T	C	MI.6964	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	155	52	L	P	cTa/cCa	-1,26	0	0	probably_damaging	0,94	deleterious	0,03	neutral	2,33	deleterious	-3,21	deleterious	-5,35	high_impact	3,52	damaging	0,59	damaging	0,01	deleterious	3,8	23,4	0,02	0,35	neutral	0,46	disease	0,86	disease	0,68	disease	0,74	5	deleterious	0,99	neutral	0,05	deleterious	6	deleterious	0,82	low_impact	-2,03	medium_impact	-0,67	medium_impact	1,97	0,27	0,8	20,31	27,93	N	0,25	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9361	9361	T	A	MI.6965	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	155	52	L	Q	cTa/cAa	-1,26	0	0	possibly_damaging	0,78	deleterious	0,04	neutral	2,33	neutral	-2,6	deleterious	-4,46	high_impact	3,87	neutral	0,6	damaging	0,02	deleterious	4	23,6	0,04	0,35	neutral	0,37	disease	0,74	disease	0,55	disease	0,66	3	neutral	0,97	neutral	0,13	deleterious	5	deleterious	0,66	low_impact	-1,4	medium_impact	-0,6	high_impact	2,29	0,31	0,8	20,31	27,93	N	0,35	N	0,97	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9363	9363	A	T	MI.6966	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	157	53	T	S	Acc/Tcc	-6,58	0	0	probably_damaging	0,98	neutral	0,41	neutral	2,49	neutral	-0,51	deleterious	-3,32	low_impact	1,48	damaging	0,53	damaging	0,11	neutral	1,28	12,18	0,36	0,5	neutral	0,18	neutral	0,44	neutral	0,4	neutral	0,43	1	neutral	0,97	neutral	0,22	neutral	-2	deleterious	0,67	low_impact	-2,51	medium_impact	0,1	medium_impact	0,14	0,61	0,8	76,63	10,86	N	0,27	N	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9363	9363	A	G	MI.6967	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	157	53	T	A	Acc/Gcc	-6,58	0	0	probably_damaging	0,98	neutral	0,34	neutral	2,48	neutral	-0,65	deleterious	-4,07	medium_impact	3,04	damaging	0,48	damaging	0,06	deleterious	2,95	22,1	0,21	0,45	neutral	0,12	disease	0,61	disease	0,51	neutral	0,47	1	neutral	0,98	neutral	0,18	deleterious	1	deleterious	0,67	low_impact	-2,51	medium_impact	0,03	medium_impact	1,54	0,46	0,8	76,63	10,86	N	0,31	N	0,44	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9363	9363	A	C	MI.6968	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	157	53	T	P	Acc/Ccc	-6,58	0	0	probably_damaging	1	neutral	0,06	neutral	2,44	neutral	-2,61	deleterious	-5,08	high_impact	3,6	damaging	0,46	damaging	0,03	deleterious	3,29	22,8	0,05	0,35	neutral	0,44	disease	0,84	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	-0,49	high_impact	2,04	0,35	0,8	76,63	10,86	N	0,32	N	0,98	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9364	9364	C	T	MI.6969	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	158	53	T	I	aCc/aTc	3,6	0,99	0	probably_damaging	1	neutral	0,55	neutral	2,55	neutral	-0,63	deleterious	-4,58	low_impact	1,3	damaging	0,56	damaging	0,15	deleterious	3,7	23,3	0,1	0,4	neutral	0,14	disease	0,68	neutral	0,4	neutral	0,47	1	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,7	low_impact	-3,78	medium_impact	0,24	medium_impact	-0,02	0,65	0,8	76,63	10,86	N	0,31	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8854	8854	G	T	MI.697	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	328	110	A	S	Gcg/Tcg	1,29	0,99	0,01	benign	0,19	deleterious	0,03	neutral	4,3	neutral	-1,32	neutral	-1,78	neutral_impact	0,34	neutral	0,89	neutral	0,74	deleterious	1,86	15,37	0,33	0,65	disease	0,61	disease	0,66	neutral	0,47	neutral	0,49	0	neutral	0,97	neutral	0,42	neutral	-2	neutral	0,34	medium_impact	-0,16	medium_impact	-0,56	medium_impact	-0,81	0,84	0,9	22,12	15,91	N	0,43	N	0,95	polymorphism	0,82	0,02	rs386829055	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9364	9364	C	A	MI.6970	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	158	53	T	N	aCc/aAc	3,6	0,99	0	probably_damaging	1	neutral	0,1	neutral	2,44	neutral	-2,19	deleterious	-4,27	medium_impact	2,9	damaging	0,5	damaging	0,03	deleterious	3,58	23,2	0,23	0,45	neutral	0,33	disease	0,78	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,74	low_impact	-3,78	medium_impact	-0,35	medium_impact	1,42	0,52	0,8	76,63	10,86	N	0,38	N	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9364	9364	C	G	MI.6971	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	158	53	T	S	aCc/aGc	3,6	0,99	0	probably_damaging	0,98	neutral	0,41	neutral	2,49	neutral	-0,51	deleterious	-3,32	low_impact	1,48	damaging	0,53	damaging	0,11	neutral	1,47	13,14	0,36	0,5	neutral	0,18	neutral	0,44	neutral	0,4	neutral	0,43	1	neutral	0,97	neutral	0,22	neutral	-2	deleterious	0,67	low_impact	-2,51	medium_impact	0,1	medium_impact	0,14	0,61	0,8	76,63	10,86	N	0,39	N	0,77	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9366	9366	A	G	MI.6972	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	160	54	M	V	Ata/Gta	-20	0	0	benign	0,01	neutral	0,51	neutral	2,53	neutral	-0,21	neutral	-2,44	medium_impact	2,79	neutral	0,62	neutral	0,64	deleterious	0,77	9,26	0,26	0,45	neutral	0,13	disease	0,62	disease	0,51	neutral	0,41	2	neutral	0,48	deleterious	0,75	neutral	-3	neutral	0,18	medium_impact	1,07	medium_impact	0,2	medium_impact	1,32	0,32	0,8	34,48	14,35	N	0,39	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9366	9366	A	T	MI.6973	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	160	54	M	L	Ata/Tta	-20	0	0	benign	0	neutral	1	neutral	2,66	neutral	1,28	neutral	-1,92	low_impact	1,38	damaging	0,6	neutral	0,69	neutral	1,44	13,02	0,28	0,45	neutral	0,13	disease	0,66	disease	0,58	neutral	0,44	1	neutral	0	deleterious	1	neutral	-6	neutral	0,19	high_impact	2,05	high_impact	1,9	medium_impact	0,05	0,3	0,8	34,48	14,35	N	0,37	N	0,23	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9366	9366	A	C	MI.6974	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	160	54	M	L	Ata/Cta	-20	0	0	benign	0	neutral	1	neutral	2,66	neutral	1,28	neutral	-1,92	low_impact	1,38	damaging	0,6	neutral	0,69	neutral	1,26	12,06	0,28	0,45	neutral	0,13	disease	0,66	disease	0,58	neutral	0,44	1	neutral	0	deleterious	1	neutral	-6	neutral	0,19	high_impact	2,05	high_impact	1,9	medium_impact	0,05	0,3	0,8	34,48	14,35	N	0,37	N	0,23	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9367	9367	T	C	MI.6975	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	161	54	M	T	aTa/aCa	3,83	0,99	0	benign	0,03	neutral	0,72	neutral	2,5	neutral	-1,47	deleterious	-3,26	medium_impact	3,16	neutral	0,68	neutral	0,61	neutral	0,95	10,37	0,1	0,4	neutral	0,21	disease	0,71	disease	0,53	neutral	0,5	0	neutral	0,23	deleterious	0,85	neutral	-3	neutral	0,22	medium_impact	0,6	medium_impact	0,43	medium_impact	1,65	0,12	0,8	34,48	14,35	N	0,49	N	0,88	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9367	9367	T	A	MI.6976	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	161	54	M	K	aTa/aAa	3,83	0,99	0	benign	0,01	neutral	0,28	neutral	2,46	neutral	-2,5	deleterious	-3,79	medium_impact	3,4	neutral	0,65	neutral	0,43	deleterious	1,96	15,96	0,03	0,35	neutral	0,25	disease	0,84	disease	0,71	disease	0,74	5	neutral	0,71	deleterious	0,64	neutral	-3	neutral	0,26	medium_impact	1,07	medium_impact	-0,04	medium_impact	1,86	0,17	0,8	34,48	14,35	P	0,54	P	0,95	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9368	9368	A	C	MI.6977	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	162	54	M	I	atA/atC	5,91	1	0	benign	0,01	neutral	0,62	neutral	2,52	neutral	-0,29	deleterious	-2,53	medium_impact	2,63	neutral	0,68	neutral	0,63	neutral	1,3	12,29	0,27	0,45	neutral	0,19	disease	0,68	disease	0,58	disease	0,5	0	neutral	0,36	deleterious	0,81	neutral	-3	neutral	0,22	medium_impact	1,07	medium_impact	0,31	medium_impact	1,17	0,36	0,8	34,48	14,35	P	0,56	P	0,82	disease_causing	1	0,08	rs386829076	Likely benign	not_provided	RCV000224115.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	9368	9368	A	T	MI.6978	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	162	54	M	I	atA/atT	5,91	1	0	benign	0,01	neutral	0,62	neutral	2,52	neutral	-0,29	deleterious	-2,53	medium_impact	2,63	neutral	0,68	neutral	0,63	neutral	1,4	12,81	0,27	0,45	neutral	0,19	disease	0,68	disease	0,58	disease	0,5	0	neutral	0,36	deleterious	0,81	neutral	-3	neutral	0,22	medium_impact	1,07	medium_impact	0,31	medium_impact	1,17	0,36	0,8	34,48	14,35	P	0,56	P	0,82	disease_causing	1	0,08	rs386829076	Likely benign	not_provided	RCV000224115.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	9369	9369	T	A	MI.6979	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	163	55	Y	N	Tac/Aac	0,13	0	0	benign	0,1	neutral	0,28	neutral	2,27	neutral	-1,81	deleterious	-4,92	medium_impact	3,14	neutral	0,65	neutral	0,4	deleterious	1,99	16,12	0,11	0,4	neutral	0,25	disease	0,65	neutral	0,48	neutral	0,49	0	neutral	0,68	deleterious	0,59	neutral	-3	neutral	0,22	medium_impact	0,06	medium_impact	-0,04	medium_impact	1,63	0,31	0,8	26,82	26,66	N	0,45	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8855	8855	C	T	MI.698	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	329	110	A	V	gCg/gTg	0,82	0,99	0	benign	0,19	deleterious	0,04	neutral	4,42	neutral	1,18	neutral	-1,15	neutral_impact	0,04	neutral	0,87	neutral	0,59	deleterious	2,53	19,64	0,36	0,65	neutral	0,31	disease	0,73	disease	0,51	neutral	0,42	2	neutral	0,95	neutral	0,43	neutral	-2	neutral	0,33	medium_impact	-0,16	medium_impact	-0,49	low_impact	-1,06	0,72	0,9	22,12	15,91	N	0,43	N	0,75	polymorphism	0,79	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9369	9369	T	G	MI.6980	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	163	55	Y	D	Tac/Gac	0,13	0	0	benign	0,13	neutral	0,16	neutral	2,26	neutral	-2,48	deleterious	-5,34	medium_impact	3,14	neutral	0,66	neutral	0,35	deleterious	1,98	16,11	0,05	0,35	neutral	0,19	disease	0,69	disease	0,58	disease	0,7	4	neutral	0,82	deleterious	0,52	neutral	-3	neutral	0,33	medium_impact	-0,07	medium_impact	-0,22	medium_impact	1,63	0,28	0,8	26,82	26,66	N	0,39	N	0,95	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9369	9369	T	C	MI.6981	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	163	55	Y	H	Tac/Cac	0,13	0	0	benign	0	neutral	0,33	neutral	2,26	neutral	-2,19	deleterious	-3,15	medium_impact	3,14	neutral	0,71	neutral	0,43	neutral	1,41	12,86	0,16	0,45	neutral	0,25	disease	0,5	disease	0,56	disease	0,65	3	neutral	0,67	deleterious	0,67	neutral	-3	neutral	0,15	high_impact	2,05	medium_impact	0,02	medium_impact	1,63	0,34	0,8	26,82	26,66	N	0,44	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9370	9370	A	T	MI.6982	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	164	55	Y	F	tAc/tTc	0,13	0	0	benign	0	neutral	0,86	neutral	2,39	neutral	1,08	neutral	-0,83	neutral_impact	-0,15	neutral	0,79	neutral	0,93	neutral	-0,18	1,19	0,28	0,45	neutral	0,11	neutral	0,13	neutral	0,29	neutral	0,21	6	neutral	0,14	deleterious	0,93	neutral	-6	neutral	0,12	high_impact	2,05	medium_impact	0,64	low_impact	-1,32	0,42	0,8	26,82	26,66	N	0,37	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9370	9370	A	G	MI.6983	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	164	55	Y	C	tAc/tGc	0,13	0	0	possibly_damaging	0,58	neutral	0,12	neutral	2,26	neutral	-2,15	deleterious	-3,98	medium_impact	2,34	neutral	0,82	neutral	0,57	deleterious	3,09	22,5	0,06	0,35	neutral	0,37	disease	0,72	neutral	0,43	disease	0,52	0	neutral	0,88	neutral	0,27	NA	0	deleterious	0,58	low_impact	-1,01	medium_impact	-0,3	medium_impact	0,92	0,13	0,8	26,82	26,66	N	0,35	N	0,57	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9370	9370	A	C	MI.6984	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	164	55	Y	S	tAc/tCc	0,13	0	0	benign	0,08	neutral	0,42	neutral	2,31	neutral	-0,56	deleterious	-4,4	low_impact	1,7	neutral	0,71	neutral	0,6	neutral	1,69	14,35	0,07	0,35	neutral	0,14	disease	0,53	neutral	0,47	neutral	0,46	1	neutral	0,53	deleterious	0,67	neutral	-6	neutral	0,23	medium_impact	0,16	medium_impact	0,11	medium_impact	0,34	0,37	0,8	26,82	26,66	N	0,37	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9372	9372	C	G	MI.6985	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	166	56	Q	E	Caa/Gaa	-7,28	0	0	possibly_damaging	0,84	neutral	0,07	neutral	2,5	neutral	-1,37	deleterious	-2,66	high_impact	3,52	neutral	0,67	damaging	0,02	deleterious	2,94	22	0,28	0,45	neutral	0,13	disease	0,67	disease	0,55	disease	0,63	3	neutral	0,96	neutral	0,12	deleterious	1	deleterious	0,66	low_impact	-1,57	medium_impact	-0,45	medium_impact	1,97	0,51	0,8	74,71	11,45	N	0,3	N	0,95	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9372	9372	C	A	MI.6986	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	166	56	Q	K	Caa/Aaa	-7,28	0	0	probably_damaging	0,92	neutral	0,29	neutral	2,5	neutral	-1,39	deleterious	-3,55	medium_impact	2,89	neutral	0,63	damaging	0,02	deleterious	3,94	23,5	0,19	0,45	neutral	0,13	disease	0,68	disease	0,58	disease	0,6	2	neutral	0,94	neutral	0,19	deleterious	1	deleterious	0,64	low_impact	-1,9	medium_impact	-0,03	medium_impact	1,41	0,39	0,8	74,71	11,45	N	0,27	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9373	9373	A	C	MI.6987	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	167	56	Q	P	cAa/cCa	4,52	1	0	probably_damaging	0,98	neutral	0,06	neutral	2,49	neutral	-1,43	deleterious	-5,37	medium_impact	3,31	neutral	0,62	damaging	0,05	deleterious	3,24	22,8	0,04	0,35	neutral	0,34	disease	0,84	disease	0,64	disease	0,72	4	deleterious	0,99	neutral	0,04	deleterious	1	deleterious	0,8	low_impact	-2,51	medium_impact	-0,49	medium_impact	1,78	0,34	0,8	74,71	11,45	N	0,41	N	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9373	9373	A	T	MI.6988	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	167	56	Q	L	cAa/cTa	4,52	1	0	probably_damaging	0,92	neutral	0,59	neutral	2,64	neutral	0,46	deleterious	-6,3	low_impact	1,3	damaging	0,5	damaging	0,06	deleterious	3,68	23,3	0,08	0,35	neutral	0,15	disease	0,64	neutral	0,34	neutral	0,44	1	neutral	0,91	neutral	0,34	neutral	-2	deleterious	0,68	low_impact	-1,9	medium_impact	0,28	medium_impact	-0,02	0,16	0,8	74,71	11,45	N	0,34	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9373	9373	A	G	MI.6989	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	167	56	Q	R	cAa/cGa	4,52	1	0	probably_damaging	0,95	neutral	0,31	neutral	2,51	neutral	-1,1	deleterious	-3,56	medium_impact	2,97	neutral	0,68	damaging	0,03	deleterious	3,35	22,9	0,19	0,45	neutral	0,19	disease	0,7	disease	0,57	disease	0,65	3	neutral	0,96	neutral	0,18	deleterious	1	deleterious	0,7	low_impact	-2,11	medium_impact	-0,01	medium_impact	1,48	0,15	0,8	74,71	11,45	N	0,42	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8855	8855	C	A	MI.699	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	329	110	A	E	gCg/gAg	0,82	0,99	0	possibly_damaging	0,48	deleterious	0	neutral	4,27	deleterious	-3,02	deleterious	-3,27	low_impact	1,7	neutral	0,84	neutral	0,46	deleterious	2,85	21,6	0,15	0,65	disease	0,82	disease	0,88	disease	0,62	disease	0,76	5	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,59	medium_impact	-0,72	low_impact	-1,4	medium_impact	0,36	0,79	0,9	22,12	15,91	N	0,34	N	0,99	polymorphism	0,68	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9374	9374	A	C	MI.6990	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	168	56	Q	H	caA/caC	8,69	1	0	probably_damaging	0,99	neutral	0,15	neutral	2,47	neutral	-2,19	deleterious	-4,42	high_impact	3,52	neutral	0,63	damaging	0,03	deleterious	3,44	23	0,2	0,45	neutral	0,31	disease	0,64	neutral	0,48	disease	0,51	0	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,74	low_impact	-2,81	medium_impact	-0,24	medium_impact	1,97	0,46	0,8	74,71	11,45	P	0,54	P	0,98	polymorphism	1	0,24	rs386829077	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9374	9374	A	T	MI.6991	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	168	56	Q	H	caA/caT	8,69	1	0	probably_damaging	0,99	neutral	0,15	neutral	2,47	neutral	-2,19	deleterious	-4,42	high_impact	3,52	neutral	0,63	damaging	0,03	deleterious	3,48	23,1	0,2	0,45	neutral	0,31	disease	0,64	neutral	0,48	disease	0,51	0	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,74	low_impact	-2,81	medium_impact	-0,24	medium_impact	1,97	0,46	0,8	74,71	11,45	P	0,55	P	0,98	polymorphism	1	0,24	rs386829077	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9375	9375	T	C	MI.6992	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	169	57	W	R	Tga/Cga	2,67	1	0	probably_damaging	1	neutral	0,62	neutral	1,08	deleterious	-6,27	deleterious	-12,91	high_impact	4,08	neutral	0,72	damaging	0,03	deleterious	3,49	23,1	0,03	0,35	neutral	0,2	disease	0,8	disease	0,82	disease	0,73	5	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	0,31	high_impact	2,47	0,07	0,8	74,33	11,3	N	0,44	N	0,99	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9375	9375	T	G	MI.6993	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	169	57	W	G	Tga/Gga	2,67	1	0	probably_damaging	1	neutral	0,36	neutral	1,08	deleterious	-6,23	deleterious	-11,99	high_impact	4,63	neutral	0,61	damaging	0,02	deleterious	3,78	23,4	0,04	0,35	neutral	0,29	disease	0,77	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,75	low_impact	-3,78	medium_impact	0,05	high_impact	2,97	0,07	0,8	74,33	11,3	P	0,49	N	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9376	9376	G	T	MI.6994	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	170	57	W	L	tGa/tTa	5,91	1	0	probably_damaging	1	neutral	0,7	neutral	1,12	deleterious	-4,94	deleterious	-11,99	high_impact	4,63	neutral	0,61	damaging	0,02	deleterious	4,15	23,8	0,06	0,35	neutral	0,23	disease	0,73	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,74	low_impact	-3,78	medium_impact	0,4	high_impact	2,97	0,06	0,8	74,33	11,3	N	0,5	N	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9376	9376	G	C	MI.6995	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	170	57	W	S	tGa/tCa	5,91	1	0	probably_damaging	1	neutral	0,46	neutral	1,08	deleterious	-6,14	deleterious	-12,91	high_impact	4,63	neutral	0,65	damaging	0,02	deleterious	3,89	23,5	0,04	0,35	neutral	0,18	disease	0,84	disease	0,77	disease	0,75	5	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,77	low_impact	-3,78	medium_impact	0,15	high_impact	2,97	0,08	0,8	74,33	11,3	N	0,46	N	0,97	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9377	9377	A	T	MI.6996	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	171	57	W	C	tgA/tgT	7,53	1	0,08	probably_damaging	1	neutral	0,17	neutral	1,06	deleterious	-7,73	deleterious	-11,99	high_impact	4,63	neutral	0,67	damaging	0,02	deleterious	4,01	23,6	0,04	0,35	disease	0,58	disease	0,83	disease	0,8	disease	0,78	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,2	high_impact	2,97	0,1	0,8	74,33	11,3	N	0,52	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9377	9377	A	C	MI.6997	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	171	57	W	C	tgA/tgC	7,53	1	0,08	probably_damaging	1	neutral	0,17	neutral	1,06	deleterious	-7,73	deleterious	-11,99	high_impact	4,63	neutral	0,67	damaging	0,02	deleterious	4,03	23,6	0,04	0,35	disease	0,58	disease	0,83	disease	0,8	disease	0,78	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,2	high_impact	2,97	0,1	0,8	74,33	11,3	N	0,51	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9378	9378	T	G	MI.6998	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	172	58	W	G	Tgg/Ggg	1,05	1	0	probably_damaging	0,99	neutral	0,32	neutral	2,42	neutral	-2,63	deleterious	-11,99	medium_impact	3,15	neutral	0,61	neutral	0,36	deleterious	3,86	23,5	0,05	0,35	neutral	0,13	disease	0,74	disease	0,71	disease	0,67	3	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,71	low_impact	-2,81	medium_impact	0,01	medium_impact	1,64	0,18	0,8	74,71	11,62	N	0,39	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9378	9378	T	C	MI.6999	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	172	58	W	R	Tgg/Cgg	1,05	1	0	probably_damaging	1	neutral	0,4	neutral	2,45	neutral	-2,54	deleterious	-12,91	high_impact	4,08	damaging	0,59	damaging	0,17	deleterious	3,52	23,1	0,03	0,35	neutral	0,14	disease	0,79	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,74	low_impact	-3,78	medium_impact	0,09	high_impact	2,47	0,16	0,8	74,71	11,62	N	0,42	N	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8530	8530	A	G	MI.7	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	4	2	N	D	Aac/Gac	7,3	1	0	probably_damaging	0,95	deleterious	0,03	neutral	4,64	neutral	-0,68	deleterious	-3,06	low_impact	1,9	neutral	0,86	neutral	0,58	deleterious	3,48	23,1	0,84	0,85	neutral	0,4	neutral	0,27	neutral	0,12	neutral	0,46	1	deleterious	0,99	neutral	0,04	deleterious	2	deleterious	0,64	low_impact	-1,97	medium_impact	-0,56	medium_impact	0,53	0,39	0,9	41,59	7,23	P	0,57	P	0,96	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8557	8557	G	T	MI.70	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	31	11	A	S	Gcc/Tcc	-0,8	0	0,02	benign	0,19	neutral	0,96	neutral	4,75	neutral	0,13	neutral	0,8	neutral_impact	-1,72	neutral	0,85	neutral	0,9	deleterious	2,73	21	0,5	0,65	neutral	0,31	neutral	0,08	neutral	0,16	neutral	0,28	4	neutral	0,12	deleterious	0,89	neutral	-6	neutral	0,2	medium_impact	-0,16	medium_impact	1,07	low_impact	-2,57	0,64	0,9	23,45	19,76	N	0,35	N	0,53	polymorphism	1	0,01	rs386829040	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8855	8855	C	G	MI.700	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	329	110	A	G	gCg/gGg	0,82	0,99	0	benign	0,19	neutral	0,05	neutral	4,28	neutral	-1,35	deleterious	-3,23	neutral_impact	0,23	neutral	0,9	neutral	0,54	deleterious	2,04	16,44	0,2	0,65	neutral	0,4	disease	0,68	neutral	0,45	disease	0,51	0	neutral	0,94	neutral	0,43	neutral	-6	neutral	0,34	medium_impact	-0,16	medium_impact	-0,43	medium_impact	-0,9	0,76	0,9	22,12	15,91	N	0,47	N	0,86	polymorphism	0,83	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9379	9379	G	C	MI.7000	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	173	58	W	S	tGg/tCg	7,53	1	0	probably_damaging	1	neutral	0,41	neutral	2,45	neutral	-1,71	deleterious	-12,91	high_impact	3,54	damaging	0,56	neutral	0,34	deleterious	3,95	23,6	0,05	0,35	neutral	0,14	disease	0,81	disease	0,69	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	0,1	medium_impact	1,99	0,18	0,8	74,71	11,62	N	0,44	N	0,97	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9379	9379	G	T	MI.7001	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	173	58	W	L	tGg/tTg	7,53	1	0	probably_damaging	0,99	neutral	0,68	neutral	2,53	neutral	-0,39	deleterious	-11,99	medium_impact	3,11	damaging	0,53	neutral	0,37	deleterious	4,15	23,8	0,07	0,35	neutral	0,12	disease	0,73	disease	0,68	disease	0,66	3	deleterious	0,99	neutral	0,35	deleterious	1	deleterious	0,72	low_impact	-2,81	medium_impact	0,38	medium_impact	1,61	0,18	0,8	74,71	11,62	N	0,48	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9380	9380	G	T	MI.7002	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	174	58	W	C	tgG/tgT	6,14	1	0,02	probably_damaging	1	neutral	0,18	neutral	2,39	deleterious	-3,3	deleterious	-11,99	high_impact	4,43	neutral	0,61	damaging	0,26	deleterious	4,07	23,7	0,04	0,35	neutral	0,4	disease	0,83	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	-0,18	high_impact	2,79	0,21	0,8	74,71	11,62	N	0,48	N	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9380	9380	G	C	MI.7003	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	174	58	W	C	tgG/tgC	6,14	1	0,02	probably_damaging	1	neutral	0,18	neutral	2,39	deleterious	-3,3	deleterious	-11,99	high_impact	4,43	neutral	0,61	damaging	0,26	deleterious	3,92	23,5	0,04	0,35	neutral	0,4	disease	0,83	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	-0,18	high_impact	2,79	0,21	0,8	74,71	11,62	N	0,47	N	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9381	9381	C	G	MI.7004	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	175	59	R	G	Cgc/Ggc	2,21	1	0	probably_damaging	1	neutral	0,33	neutral	1,77	deleterious	-4,37	deleterious	-6,45	medium_impact	2,66	neutral	0,62	damaging	0,01	deleterious	4,08	23,7	0,05	0,35	disease	0,52	disease	0,7	disease	0,68	disease	0,55	1	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,8	low_impact	-3,78	medium_impact	0,02	medium_impact	1,2	0,28	0,8	74,33	11,45	N	0,31	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9381	9381	C	T	MI.7005	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	175	59	R	C	Cgc/Tgc	2,21	1	0	probably_damaging	1	neutral	0,18	neutral	1,74	deleterious	-6,51	deleterious	-7,37	high_impact	4,37	neutral	0,65	damaging	0,01	deleterious	4,94	25	0,08	0,35	disease	0,81	disease	0,85	disease	0,68	disease	0,75	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	-0,18	high_impact	2,73	0,64	0,8	74,33	11,45	N	0,45	N	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9381	9381	C	A	MI.7006	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	175	59	R	S	Cgc/Agc	2,21	1	0	probably_damaging	1	neutral	0,41	neutral	1,8	deleterious	-3,5	deleterious	-5,53	medium_impact	1,97	neutral	0,65	damaging	0,01	deleterious	4,44	24,2	0,06	0,35	neutral	0,39	disease	0,73	disease	0,66	disease	0,53	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,81	low_impact	-3,78	medium_impact	0,1	medium_impact	0,58	0,32	0,8	74,33	11,45	N	0,29	N	0,88	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9382	9382	G	T	MI.7007	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	176	59	R	L	cGc/cTc	1,52	1	0	probably_damaging	0,99	neutral	0,68	neutral	1,78	deleterious	-3,96	deleterious	-6,45	high_impact	3,67	neutral	0,62	damaging	0,01	deleterious	4,26	23,9	0,06	0,35	neutral	0,46	disease	0,87	disease	0,62	disease	0,71	4	deleterious	0,99	neutral	0,35	deleterious	2	deleterious	0,83	low_impact	-2,81	medium_impact	0,38	high_impact	2,11	0,12	0,8	74,33	11,45	N	0,37	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9382	9382	G	C	MI.7008	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	176	59	R	P	cGc/cCc	1,52	1	0	probably_damaging	1	neutral	0,2	neutral	1,76	deleterious	-4,92	deleterious	-6,45	high_impact	4,02	damaging	0,59	damaging	0,02	deleterious	4,14	23,8	0,02	0,35	disease	0,59	disease	0,85	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	-0,15	high_impact	2,42	0,19	0,8	74,33	11,45	N	0,44	N	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9382	9382	G	A	MI.7009	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	176	59	R	H	cGc/cAc	1,52	1	0	probably_damaging	1	neutral	0,54	neutral	1,77	deleterious	-4,28	deleterious	-4,61	high_impact	4,37	neutral	0,61	damaging	0,01	deleterious	4,29	24	0,13	0,4	neutral	0,29	disease	0,74	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,77	low_impact	-3,78	medium_impact	0,23	high_impact	2,73	0,73	0,85	74,33	11,45	N	0,4	N	1	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8857	8857	G	A	MI.701	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	331	111	G	S	Ggc/Agc	-13,06	0	0,01	benign	0,15	neutral	1	neutral	4,43	neutral	0,26	neutral	-2,1	neutral_impact	0,66	neutral	0,8	neutral	0,64	neutral	1,22	11,86	0,36	0,65	disease	0,51	neutral	0,47	neutral	0,35	neutral	0,4	2	neutral	0,15	deleterious	0,93	neutral	-6	neutral	0,27	medium_impact	-0,04	high_impact	1,98	medium_impact	-0,53	0,84	0,9	14,6	14,23	N	0,18	N	0,19	polymorphism	1	0,03	rs201017581	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9384	9384	G	T	MI.7010	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	178	60	D	Y	Gat/Tat	-1,03	0	0	probably_damaging	1	neutral	1	neutral	1,26	deleterious	-6,83	deleterious	-8,3	high_impact	4,54	neutral	0,62	damaging	0,02	deleterious	3,9	23,5	0,03	0,35	neutral	0,5	disease	0,86	disease	0,71	disease	0,76	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,84	low_impact	-3,78	high_impact	1,9	high_impact	2,89	0,1	0,8	75,1	11,32	N	0,34	N	1	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9384	9384	G	A	MI.7011	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	178	60	D	N	Gat/Aat	-1,03	0	0	probably_damaging	1	neutral	0,3	neutral	1,32	deleterious	-4,5	deleterious	-4,61	medium_impact	3,04	damaging	0,56	damaging	0,02	deleterious	4,14	23,8	0,35	0,5	neutral	0,36	disease	0,72	disease	0,68	disease	0,63	3	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,78	low_impact	-3,78	medium_impact	-0,02	medium_impact	1,54	0,91	0,95	75,1	11,32	N	0,28	N	0,96	polymorphism	1	0,15	.	.	.	.	.	.	COSM1138427	.	.	.	.	.	.	.	.
chrM	9384	9384	G	C	MI.7012	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	178	60	D	H	Gat/Cat	-1,03	0	0	probably_damaging	1	neutral	0,54	neutral	1,27	deleterious	-6,1	deleterious	-6,46	medium_impact	3,26	damaging	0,57	damaging	0,02	deleterious	3,61	23,2	0,05	0,35	disease	0,53	disease	0,73	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,81	low_impact	-3,78	medium_impact	0,23	medium_impact	1,74	0,54	0,8	75,1	11,32	N	0,21	N	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9385	9385	A	G	MI.7013	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	179	60	D	G	gAt/gGt	7,3	1	0	probably_damaging	1	neutral	0,33	neutral	1,3	deleterious	-4,99	deleterious	-6,46	high_impact	3,74	damaging	0,59	damaging	0,01	deleterious	4,02	23,6	0,05	0,35	neutral	0,45	disease	0,75	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	0,02	high_impact	2,17	0,26	0,8	75,1	11,32	N	0,51	P	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9385	9385	A	T	MI.7014	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	179	60	D	V	gAt/gTt	7,3	1	0	probably_damaging	1	neutral	0,53	neutral	1,27	deleterious	-5,97	deleterious	-8,3	high_impact	4,54	damaging	0,56	damaging	0,02	deleterious	3,83	23,4	0,03	0,35	neutral	0,39	disease	0,82	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	0,22	high_impact	2,89	0,07	0,8	75,1	11,32	N	0,44	N	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9385	9385	A	C	MI.7015	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	179	60	D	A	gAt/gCt	7,3	1	0	probably_damaging	1	neutral	0,5	neutral	1,31	deleterious	-4,76	deleterious	-7,38	medium_impact	3,3	damaging	0,59	damaging	0,02	deleterious	3,75	23,3	0,04	0,35	neutral	0,32	disease	0,76	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,79	low_impact	-3,78	medium_impact	0,19	medium_impact	1,78	0,22	0,8	75,1	11,32	N	0,41	N	0,83	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9386	9386	T	A	MI.7016	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	180	60	D	E	gaT/gaA	7,07	1	0	probably_damaging	0,98	neutral	0,27	neutral	1,37	deleterious	-3,63	deleterious	-3,69	medium_impact	3,23	neutral	0,6	damaging	0,02	deleterious	3,99	23,6	0,19	0,45	neutral	0,26	disease	0,64	disease	0,57	neutral	0,46	1	neutral	0,98	neutral	0,15	deleterious	1	deleterious	0,75	low_impact	-2,51	medium_impact	-0,06	medium_impact	1,71	0,51	0,8	75,1	11,32	P	0,54	P	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9386	9386	T	G	MI.7017	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	180	60	D	E	gaT/gaG	7,07	1	0	probably_damaging	0,98	neutral	0,27	neutral	1,37	deleterious	-3,63	deleterious	-3,69	medium_impact	3,23	neutral	0,6	damaging	0,02	deleterious	3,81	23,4	0,19	0,45	neutral	0,26	disease	0,64	disease	0,57	neutral	0,46	1	neutral	0,98	neutral	0,15	deleterious	1	deleterious	0,75	low_impact	-2,51	medium_impact	-0,06	medium_impact	1,71	0,51	0,8	75,1	11,32	P	0,53	P	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9387	9387	G	A	MI.7018	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	181	61	V	M	Gta/Ata	-2,88	0	0	benign	0,42	neutral	0,18	neutral	2	neutral	-2,5	neutral	-2,35	medium_impact	2,9	neutral	0,63	neutral	0,45	deleterious	3,48	23,1	0,17	0,45	neutral	0,21	disease	0,5	neutral	0,42	neutral	0,46	1	neutral	0,79	neutral	0,38	neutral	-3	neutral	0,43	medium_impact	-0,73	medium_impact	-0,18	medium_impact	1,42	0,97	1	72,41	10,38	N	0,54	P	0,69	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	G9387A	Asthenozoospermia	-	+	Reported	1
chrM	9387	9387	G	T	MI.7019	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	181	61	V	L	Gta/Tta	-2,88	0	0	benign	0,01	neutral	0,54	neutral	2,18	neutral	-0,68	neutral	-1,95	medium_impact	2,73	neutral	0,64	neutral	0,42	neutral	1,68	14,28	0,17	0,45	neutral	0,13	disease	0,59	disease	0,55	disease	0,56	1	neutral	0,45	deleterious	0,77	neutral	-3	neutral	0,16	medium_impact	1,07	medium_impact	0,23	medium_impact	1,26	0,68	0,85	72,41	10,38	N	0,31	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8857	8857	G	C	MI.702	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	331	111	G	R	Ggc/Cgc	-13,06	0	0,01	probably_damaging	0,92	neutral	0,08	neutral	4,24	neutral	-2,7	deleterious	-4,05	medium_impact	3,36	neutral	0,77	neutral	0,32	deleterious	3,88	23,5	0,13	0,65	disease	0,79	disease	0,92	disease	0,7	disease	0,78	6	neutral	0,98	neutral	0,08	deleterious	1	deleterious	0,86	low_impact	-1,76	medium_impact	-0,31	medium_impact	1,78	0,62	0,9	14,6	14,23	N	0,31	N	0,95	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9387	9387	G	C	MI.7020	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	181	61	V	L	Gta/Cta	-2,88	0	0	benign	0,01	neutral	0,54	neutral	2,18	neutral	-0,68	neutral	-1,95	medium_impact	2,73	neutral	0,64	neutral	0,42	neutral	1,58	13,73	0,17	0,45	neutral	0,13	disease	0,59	disease	0,55	disease	0,56	1	neutral	0,45	deleterious	0,77	neutral	-3	neutral	0,16	medium_impact	1,07	medium_impact	0,23	medium_impact	1,26	0,68	0,85	72,41	10,38	N	0,31	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9388	9388	T	C	MI.7021	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	182	61	V	A	gTa/gCa	-0,1	0	0	benign	0,16	neutral	0,87	neutral	1,98	neutral	-2,86	deleterious	-3,67	medium_impact	2,81	neutral	0,61	neutral	0,54	deleterious	1,89	15,51	0,09	0,35	neutral	0,14	disease	0,57	disease	0,61	disease	0,65	3	neutral	0,07	deleterious	0,86	neutral	-3	neutral	0,25	medium_impact	-0,17	medium_impact	0,66	medium_impact	1,34	0,24	0,8	72,41	10,38	N	0,28	N	0,87	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9388	9388	T	A	MI.7022	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	182	61	V	E	gTa/gAa	-0,1	0	0	possibly_damaging	0,5	neutral	1	neutral	1,94	deleterious	-4,65	deleterious	-5,52	high_impact	4,28	damaging	0,59	neutral	0,3	deleterious	4,33	24	0,02	0,35	neutral	0,27	disease	0,83	disease	0,71	disease	0,74	5	neutral	0,5	deleterious	0,75	deleterious	1	deleterious	0,51	medium_impact	-0,87	high_impact	1,9	high_impact	2,65	0,17	0,8	72,41	10,38	N	0,29	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9388	9388	T	G	MI.7023	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	182	61	V	G	gTa/gGa	-0,1	0	0	possibly_damaging	0,59	neutral	0,47	neutral	1,94	deleterious	-4,89	deleterious	-6,44	high_impact	3,94	neutral	0,61	neutral	0,34	deleterious	3,64	23,2	0,03	0,35	neutral	0,33	disease	0,71	disease	0,59	disease	0,67	3	neutral	0,58	neutral	0,44	deleterious	1	deleterious	0,64	low_impact	-1,02	medium_impact	0,16	high_impact	2,35	0,24	0,8	72,41	10,38	N	0,34	N	0,94	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9390	9390	A	T	MI.7024	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	184	62	T	S	Aca/Tca	-8,66	0	0	benign	0	neutral	0,87	neutral	2,35	neutral	0,43	neutral	-1,63	low_impact	0,94	neutral	0,72	neutral	0,75	deleterious	0,09	3,54	0,31	0,45	neutral	0,1	neutral	0,15	neutral	0,19	neutral	0,3	4	neutral	0,12	deleterious	0,94	neutral	-6	neutral	0,13	high_impact	2,05	medium_impact	0,66	medium_impact	-0,34	0,73	0,85	15,33	13,99	N	0,41	N	0,1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9390	9390	A	G	MI.7025	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	184	62	T	A	Aca/Gca	-8,66	0	0	benign	0	neutral	0,92	neutral	2,36	neutral	0,62	neutral	-0,8	low_impact	1,5	neutral	0,7	neutral	0,77	deleterious	0,38	6,43	0,23	0,45	neutral	0,11	neutral	0,25	neutral	0,38	neutral	0,42	2	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,11	high_impact	2,05	medium_impact	0,8	medium_impact	0,16	0,37	0,8	15,33	13,99	N	0,34	N	0,05	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9390	9390	A	C	MI.7026	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	184	62	T	P	Aca/Cca	-8,66	0	0	benign	0	neutral	0,37	neutral	2,27	neutral	-1,87	deleterious	-2,64	medium_impact	2,44	damaging	0,56	neutral	0,36	neutral	1,49	13,25	0,05	0,35	neutral	0,3	disease	0,64	disease	0,61	disease	0,72	4	neutral	0,63	deleterious	0,69	neutral	-3	neutral	0,23	high_impact	2,05	medium_impact	0,06	medium_impact	1	0,37	0,8	15,33	13,99	N	0,34	N	0,23	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9391	9391	C	T	MI.7027	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	185	62	T	M	aCa/aTa	-1,26	0	0	benign	0	neutral	0,25	neutral	2,3	neutral	-0,53	neutral	-0,63	low_impact	1,89	neutral	0,76	neutral	0,87	deleterious	1,91	15,65	0,1	0,4	neutral	0,2	neutral	0,25	neutral	0,39	neutral	0,43	1	neutral	0,75	deleterious	0,63	neutral	-6	neutral	0,12	high_impact	2,05	medium_impact	-0,08	medium_impact	0,51	0,6	0,8	15,33	13,99	N	0,49	N	0	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9391	9391	C	A	MI.7028	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	185	62	T	K	aCa/aAa	-1,26	0	0	benign	0	neutral	0,86	neutral	2,29	neutral	-0,76	deleterious	-2,6	medium_impact	2,24	neutral	0,67	neutral	0,49	deleterious	2,45	19,14	0,07	0,35	neutral	0,14	neutral	0,41	disease	0,59	neutral	0,46	1	neutral	0,13	deleterious	0,93	neutral	-3	neutral	0,15	high_impact	2,05	medium_impact	0,64	medium_impact	0,83	0,43	0,8	15,33	13,99	N	0,3	N	0,22	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9393	9393	C	T	MI.7029	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	187	63	R	W	Cga/Tga	-10,51	0	0	probably_damaging	1	neutral	0,09	neutral	2,31	deleterious	-4,97	deleterious	-7,38	high_impact	4,34	damaging	0,56	damaging	0,03	deleterious	5,14	25,4	0,06	0,35	disease	0,69	disease	0,88	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,38	high_impact	2,71	0,8	0,85	73,56	11,64	N	0,33	N	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8857	8857	G	T	MI.703	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	331	111	G	C	Ggc/Tgc	-13,06	0	0,01	probably_damaging	0,98	neutral	0,07	neutral	4,29	neutral	-1,21	deleterious	-4,05	medium_impact	2	neutral	0,74	neutral	0,32	deleterious	4,09	23,7	0,18	0,65	disease	0,76	disease	0,88	disease	0,59	disease	0,73	5	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,83	low_impact	-2,36	medium_impact	-0,34	medium_impact	0,62	0,7	0,9	14,6	14,23	N	0,29	N	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9393	9393	C	G	MI.7030	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	187	63	R	G	Cga/Gga	-10,51	0	0	probably_damaging	1	neutral	0,41	neutral	2,35	neutral	-1,77	deleterious	-6,46	medium_impact	3,1	damaging	0,57	damaging	0,04	deleterious	4,18	23,8	0,05	0,35	neutral	0,26	disease	0,75	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	0,1	medium_impact	1,6	0,2	0,8	73,56	11,64	N	0,22	N	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9394	9394	G	C	MI.7031	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	188	63	R	P	cGa/cCa	2,9	0,98	0	probably_damaging	1	neutral	0,26	neutral	2,34	neutral	-2,58	deleterious	-6,46	high_impact	4,34	damaging	0,55	damaging	0,03	deleterious	4,17	23,8	0,02	0,35	neutral	0,39	disease	0,86	disease	0,74	disease	0,76	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	-0,07	high_impact	2,71	0,11	0,8	73,56	11,64	P	0,49	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9394	9394	G	A	MI.7032	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	188	63	R	Q	cGa/cAa	2,9	0,98	0	probably_damaging	0,99	neutral	0,55	neutral	2,34	neutral	-0,86	deleterious	-3,69	high_impact	3,79	neutral	0,64	damaging	0,03	deleterious	4,46	24,2	0,14	0,4	neutral	0,21	disease	0,76	disease	0,63	disease	0,66	3	deleterious	0,99	neutral	0,28	deleterious	2	deleterious	0,74	low_impact	-2,81	medium_impact	0,24	high_impact	2,21	0,66	0,8	73,56	11,64	N	0,44	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9394	9394	G	T	MI.7033	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	188	63	R	L	cGa/cTa	2,9	0,98	0	probably_damaging	0,99	neutral	0,55	neutral	2,41	neutral	-1,89	deleterious	-6,46	medium_impact	3,19	neutral	0,61	damaging	0,03	deleterious	4,25	23,9	0,06	0,35	neutral	0,2	disease	0,87	disease	0,61	disease	0,71	4	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,78	low_impact	-2,81	medium_impact	0,24	medium_impact	1,68	0,08	0,8	73,56	11,64	N	0,36	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9396	9396	G	C	MI.7034	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	190	64	E	Q	Gaa/Caa	-0,1	0,9	0	probably_damaging	0,99	neutral	0,32	neutral	1,45	deleterious	-4,5	deleterious	-2,8	high_impact	4,28	damaging	0,56	damaging	0,05	deleterious	3,32	22,9	0,14	0,4	neutral	0,28	disease	0,58	disease	0,59	disease	0,64	3	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,75	low_impact	-2,81	medium_impact	0,01	high_impact	2,65	0,77	0,85	73,95	11,56	N	0,36	N	0,87	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9396	9396	G	A	MI.7035	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	190	64	E	K	Gaa/Aaa	-0,1	0,9	0	probably_damaging	1	neutral	0,25	neutral	1,47	deleterious	-4,04	deleterious	-3,72	high_impact	3,58	damaging	0,51	damaging	0,04	deleterious	4,4	24,1	0,07	0,35	neutral	0,22	disease	0,66	disease	0,68	disease	0,67	3	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	-0,08	high_impact	2,03	0,75	0,85	73,95	11,56	N	0,37	N	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9397	9397	A	C	MI.7036	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	191	64	E	A	gAa/gCa	9,15	1	0	probably_damaging	1	neutral	0,59	neutral	1,46	deleterious	-4,35	deleterious	-5,6	high_impact	3,93	damaging	0,52	damaging	0,08	deleterious	3,42	23	0,05	0,35	neutral	0,22	disease	0,63	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	0,28	high_impact	2,34	0,3	0,8	73,95	11,56	N	0,5	N	0,66	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9397	9397	A	G	MI.7037	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	191	64	E	G	gAa/gGa	9,15	1	0	probably_damaging	1	neutral	0,32	neutral	1,44	deleterious	-4,75	deleterious	-6,54	high_impact	3,52	damaging	0,52	damaging	0,06	deleterious	3,97	23,6	0,05	0,35	neutral	0,33	disease	0,59	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,77	low_impact	-3,78	medium_impact	0,01	medium_impact	1,97	0,26	0,8	73,95	11,56	N	0,51	P	0,62	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9397	9397	A	T	MI.7038	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	191	64	E	V	gAa/gTa	9,15	1	0	probably_damaging	1	neutral	0,53	neutral	1,43	deleterious	-5,36	deleterious	-6,54	high_impact	4,07	damaging	0,5	damaging	0,04	deleterious	3,91	23,5	0,03	0,35	neutral	0,42	disease	0,75	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	0,22	high_impact	2,47	0,26	0,8	73,95	11,56	N	0,51	P	0,83	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9398	9398	A	C	MI.7039	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	192	64	E	D	gaA/gaC	8,69	1	0	probably_damaging	0,98	neutral	0,18	neutral	1,51	deleterious	-3,5	deleterious	-2,8	medium_impact	3,21	damaging	0,53	damaging	0,04	deleterious	3,62	23,2	0,23	0,45	neutral	0,29	disease	0,55	disease	0,56	disease	0,62	2	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,74	low_impact	-2,51	medium_impact	-0,18	medium_impact	1,69	0,61	0,8	73,95	11,56	P	0,58	P	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8858	8858	G	C	MI.704	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	332	111	G	A	gGc/gCc	5,91	0,99	0	possibly_damaging	0,56	neutral	0,82	neutral	4,5	neutral	0,73	neutral	-0,81	neutral_impact	-0,24	neutral	0,82	neutral	0,74	deleterious	-0,01	2,48	0,44	0,65	neutral	0,37	neutral	0,17	neutral	0,28	neutral	0,24	5	neutral	0,47	deleterious	0,63	neutral	-3	deleterious	0,5	medium_impact	-0,86	medium_impact	0,66	low_impact	-1,3	0,68	0,9	14,6	14,23	N	0,45	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9398	9398	A	T	MI.7040	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	192	64	E	D	gaA/gaT	8,69	1	0	probably_damaging	0,98	neutral	0,18	neutral	1,51	deleterious	-3,5	deleterious	-2,8	medium_impact	3,21	damaging	0,53	damaging	0,04	deleterious	3,74	23,3	0,23	0,45	neutral	0,29	disease	0,55	disease	0,56	disease	0,62	2	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,74	low_impact	-2,51	medium_impact	-0,18	medium_impact	1,69	0,61	0,8	73,95	11,56	P	0,59	P	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9399	9399	A	G	MI.7041	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	193	65	S	G	Agc/Ggc	0,59	0,93	0	benign	0	neutral	0,48	neutral	2,37	neutral	0,26	neutral	1,86	neutral_impact	0,34	neutral	0,72	neutral	0,96	neutral	-1,33	0	0,18	0,45	neutral	0,15	neutral	0,03	neutral	0,26	neutral	0,19	6	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,12	high_impact	2,05	medium_impact	0,17	medium_impact	-0,88	0,5	0,8	16,09	23,32	N	0,4	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9399	9399	A	T	MI.7042	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	193	65	S	C	Agc/Tgc	0,59	0,93	0	possibly_damaging	0,88	neutral	0,18	neutral	2,07	deleterious	-3,8	deleterious	-2,68	medium_impact	3,46	damaging	0,56	neutral	0,31	deleterious	3,14	22,6	0,07	0,35	disease	0,6	disease	0,5	disease	0,66	disease	0,69	4	neutral	0,93	neutral	0,15	NA	0	deleterious	0,69	low_impact	-1,71	medium_impact	-0,18	medium_impact	1,92	0,31	0,8	16,09	23,32	N	0,42	N	0,72	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9399	9399	A	C	MI.7043	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	193	65	S	R	Agc/Cgc	0,59	0,93	0	possibly_damaging	0,79	neutral	0,46	neutral	2,09	neutral	-2,86	neutral	-2,46	medium_impact	3,46	damaging	0,53	neutral	0,32	deleterious	3,59	23,2	0,07	0,35	neutral	0,27	disease	0,5	disease	0,77	disease	0,73	5	neutral	0,78	neutral	0,34	NA	0	deleterious	0,66	low_impact	-1,43	medium_impact	0,15	medium_impact	1,92	0,27	0,8	16,09	23,32	P	0,51	P	0,6	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9400	9400	G	T	MI.7044	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	194	65	S	I	aGc/aTc	0,13	0,92	0	possibly_damaging	0,86	neutral	0,44	neutral	2,08	deleterious	-3,25	deleterious	-3,62	high_impact	3,81	neutral	0,65	neutral	0,49	deleterious	4,04	23,7	0,07	0,35	neutral	0,29	disease	0,53	disease	0,66	disease	0,7	4	neutral	0,85	neutral	0,29	deleterious	1	deleterious	0,65	low_impact	-1,64	medium_impact	0,13	high_impact	2,23	0,32	0,8	16,09	23,32	N	0,45	N	0,8	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9400	9400	G	C	MI.7045	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	194	65	S	T	aGc/aCc	0,13	0,92	0	benign	0,11	neutral	0,53	neutral	2,15	neutral	-1,6	neutral	-1,81	medium_impact	2,84	damaging	0,6	neutral	0,46	deleterious	2,94	22	0,24	0,45	neutral	0,24	neutral	0,3	disease	0,64	neutral	0,48	0	neutral	0,38	deleterious	0,71	neutral	-3	neutral	0,18	medium_impact	0,01	medium_impact	0,22	medium_impact	1,36	0,46	0,8	16,09	23,32	N	0,42	N	0,3	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9400	9400	G	A	MI.7046	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	194	65	S	N	aGc/aAc	0,13	0,92	0	benign	0,13	neutral	0,39	neutral	2,1	neutral	-2,47	neutral	-1,37	medium_impact	2,52	neutral	0,6	neutral	0,37	deleterious	1,99	16,13	0,44	0,55	neutral	0,28	neutral	0,43	disease	0,68	disease	0,51	0	neutral	0,54	deleterious	0,63	neutral	-3	neutral	0,23	medium_impact	-0,07	medium_impact	0,08	medium_impact	1,08	0,34	0,8	16,09	23,32	N	0,42	N	0,38	polymorphism	1	0,03	.	.	.	.	.	.	COSM1138429	.	.	.	.	.	.	.	.
chrM	9402	9402	A	C	MI.7047	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	196	66	T	P	Aca/Cca	-9,13	0	0	probably_damaging	0,99	neutral	0,2	neutral	1,94	deleterious	-3,8	deleterious	-5,45	high_impact	3,71	neutral	0,65	damaging	0,05	deleterious	3,49	23,1	0,04	0,35	neutral	0,28	disease	0,55	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,74	low_impact	-2,81	medium_impact	-0,15	high_impact	2,14	0,17	0,8	73,95	11,61	N	0,29	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9402	9402	A	G	MI.7048	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	196	66	T	A	Aca/Gca	-9,13	0	0	probably_damaging	0,96	neutral	0,5	neutral	2,05	neutral	-1,7	deleterious	-4,45	medium_impact	3,12	neutral	0,61	damaging	0,09	deleterious	3,42	23	0,35	0,5	neutral	0,19	neutral	0,38	disease	0,61	neutral	0,41	2	neutral	0,95	neutral	0,27	deleterious	1	deleterious	0,66	low_impact	-2,21	medium_impact	0,19	medium_impact	1,61	0,3	0,8	73,95	11,61	N	0,29	N	0,44	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9402	9402	A	T	MI.7049	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	196	66	T	S	Aca/Tca	-9,13	0	0	probably_damaging	0,96	neutral	0,41	neutral	2,05	neutral	-1,66	deleterious	-3,46	medium_impact	2,02	damaging	0,48	damaging	0,11	deleterious	3,24	22,8	0,49	0,55	neutral	0,19	neutral	0,28	neutral	0,32	neutral	0,38	2	neutral	0,96	neutral	0,23	deleterious	1	deleterious	0,67	low_impact	-2,21	medium_impact	0,1	medium_impact	0,63	0,37	0,8	73,95	11,61	N	0,34	N	0,77	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8858	8858	G	T	MI.705	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	332	111	G	V	gGc/gTc	5,91	0,99	0	probably_damaging	0,92	neutral	0,09	neutral	4,28	neutral	-1,42	deleterious	-4,05	medium_impact	2,16	neutral	0,78	neutral	0,43	deleterious	3,73	23,3	0,25	0,65	disease	0,67	disease	0,86	disease	0,53	disease	0,73	5	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,79	low_impact	-1,76	medium_impact	-0,28	medium_impact	0,75	0,63	0,9	14,6	14,23	N	0,46	N	0,94	polymorphism	0,96	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9403	9403	C	A	MI.7050	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	197	66	T	K	aCa/aAa	8,69	1	0	probably_damaging	0,99	neutral	0,29	neutral	1,99	neutral	-2,53	deleterious	-5,4	medium_impact	3,02	neutral	0,69	damaging	0,02	deleterious	4,44	24,2	0,09	0,35	neutral	0,17	neutral	0,48	disease	0,65	neutral	0,48	0	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,7	low_impact	-2,81	medium_impact	-0,03	medium_impact	1,52	0,21	0,8	73,95	11,61	P	0,52	P	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9403	9403	C	T	MI.7051	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	197	66	T	M	aCa/aTa	8,69	1	0	probably_damaging	1	neutral	0,22	neutral	1,93	deleterious	-4,28	deleterious	-5,43	medium_impact	2,92	neutral	0,64	damaging	0,01	deleterious	3,99	23,6	0,15	0,4	neutral	0,45	neutral	0,4	disease	0,64	neutral	0,44	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,7	low_impact	-3,78	medium_impact	-0,12	medium_impact	1,43	0,4	0,8	73,95	11,61	P	0,5	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9405	9405	T	C	MI.7052	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	199	67	Y	H	Tac/Cac	-13,06	0	0	probably_damaging	1	neutral	0,55	neutral	2,22	neutral	-2,19	deleterious	-3,5	medium_impact	2,27	neutral	0,64	neutral	0,32	deleterious	3,5	23,1	0,26	0,45	neutral	0,4	neutral	0,3	disease	0,58	neutral	0,49	0	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,72	low_impact	-3,78	medium_impact	0,24	medium_impact	0,85	0,12	0,8	20,31	40,32	N	0,29	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9405	9405	T	A	MI.7053	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	199	67	Y	N	Tac/Aac	-13,06	0	0	probably_damaging	1	neutral	0,31	neutral	2,22	neutral	-1,86	deleterious	-5,54	medium_impact	2,68	neutral	0,62	damaging	0,22	deleterious	3,99	23,6	0,15	0,45	neutral	0,33	disease	0,53	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	-0,01	medium_impact	1,22	0,17	0,8	20,31	40,32	N	0,29	N	0,9	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9405	9405	T	G	MI.7054	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	199	67	Y	D	Tac/Gac	-13,06	0	0	probably_damaging	1	neutral	0,21	neutral	2,24	neutral	-1,44	deleterious	-6,14	medium_impact	3,37	damaging	0,54	damaging	0,15	deleterious	3,95	23,6	0,11	0,4	neutral	0,4	disease	0,58	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,75	low_impact	-3,78	medium_impact	-0,14	medium_impact	1,84	0,19	0,8	20,31	40,32	N	0,31	N	0,97	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9406	9406	A	G	MI.7055	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	200	67	Y	C	tAc/tGc	5,68	0,99	0	probably_damaging	1	neutral	0,18	neutral	2,2	neutral	-2,82	deleterious	-5	medium_impact	2,82	damaging	0,55	damaging	0,13	deleterious	3,35	22,9	0,1	0,4	neutral	0,41	disease	0,59	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,74	low_impact	-3,78	medium_impact	-0,18	medium_impact	1,35	0,01	0,8	20,31	40,32	N	0,46	N	0,97	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9406	9406	A	C	MI.7056	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	200	67	Y	S	tAc/tCc	5,68	0,99	0	probably_damaging	0,99	neutral	0,41	neutral	2,25	neutral	-1,01	deleterious	-5,12	medium_impact	2,82	damaging	0,59	damaging	0,22	deleterious	3,54	23,1	0,11	0,4	neutral	0,14	neutral	0,46	disease	0,66	disease	0,52	0	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,7	low_impact	-2,81	medium_impact	0,1	medium_impact	1,35	0,12	0,8	20,31	40,32	N	0,48	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9406	9406	A	T	MI.7057	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	200	67	Y	F	tAc/tTc	5,68	0,99	0	probably_damaging	0,98	neutral	0,75	neutral	2,4	neutral	0,71	neutral	0,21	neutral_impact	-0,5	neutral	0,76	neutral	0,98	deleterious	0,52	7,62	0,28	0,45	neutral	0,15	neutral	0,03	neutral	0,24	neutral	0,2	6	neutral	0,98	neutral	0,39	neutral	-2	deleterious	0,65	low_impact	-2,51	medium_impact	0,46	low_impact	-1,63	0,17	0,8	20,31	40,32	P	0,57	P	0,14	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9408	9408	C	A	MI.7058	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	202	68	Q	K	Caa/Aaa	-1,26	0,01	0	probably_damaging	0,98	neutral	0,3	neutral	2,29	neutral	0,36	deleterious	-3,49	medium_impact	2,44	neutral	0,69	damaging	0,03	deleterious	3,95	23,6	0,48	0,55	neutral	0,15	disease	0,57	disease	0,6	disease	0,56	1	deleterious	0,98	neutral	0,16	deleterious	1	deleterious	0,71	low_impact	-2,51	medium_impact	-0,02	medium_impact	1	0,24	0,8	73,56	11,66	N	0,28	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9408	9408	C	G	MI.7059	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	202	68	Q	E	Caa/Gaa	-1,26	0,01	0	probably_damaging	0,95	neutral	0,28	neutral	2,31	neutral	0,58	deleterious	-2,67	low_impact	1,8	neutral	0,62	damaging	0,04	deleterious	2,99	22,2	0,48	0,55	neutral	0,12	neutral	0,34	neutral	0,35	neutral	0,4	2	neutral	0,96	neutral	0,17	neutral	-2	deleterious	0,69	low_impact	-2,11	medium_impact	-0,04	medium_impact	0,43	0,15	0,8	73,56	11,66	N	0,3	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8858	8858	G	A	MI.706	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	332	111	G	D	gGc/gAc	5,91	0,99	0	possibly_damaging	0,78	deleterious	0,03	neutral	4,23	deleterious	-3,17	deleterious	-4,04	medium_impact	3,36	neutral	0,76	neutral	0,36	deleterious	3,61	23,2	0,13	0,65	disease	0,82	disease	0,9	disease	0,68	disease	0,79	6	neutral	0,98	neutral	0,13	deleterious	4	deleterious	0,82	low_impact	-1,28	medium_impact	-0,56	medium_impact	1,78	0,48	0,9	14,6	14,23	P	0,55	P	0,73	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9409	9409	A	G	MI.7060	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	203	68	Q	R	cAa/cGa	5,45	1	0	probably_damaging	0,99	neutral	0,35	neutral	2,24	neutral	-0,24	deleterious	-3,51	medium_impact	2,75	neutral	0,72	damaging	0,02	deleterious	3,42	23	0,53	0,6	neutral	0,18	disease	0,56	disease	0,64	disease	0,64	3	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,73	low_impact	-2,81	medium_impact	0,04	medium_impact	1,28	0,1	0,8	73,56	11,66	N	0,46	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9409	9409	A	T	MI.7061	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	203	68	Q	L	cAa/cTa	5,45	1	0	probably_damaging	0,98	neutral	0,65	neutral	2,28	neutral	-0,9	deleterious	-5,93	low_impact	1,4	damaging	0,59	damaging	0,18	deleterious	3,69	23,3	0,14	0,4	neutral	0,23	neutral	0,41	neutral	0,35	neutral	0,4	2	neutral	0,98	neutral	0,34	neutral	-2	deleterious	0,72	low_impact	-2,51	medium_impact	0,35	medium_impact	0,07	0,21	0,8	73,56	11,66	N	0,39	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9409	9409	A	C	MI.7062	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	203	68	Q	P	cAa/cCa	5,45	1	0	probably_damaging	0,99	neutral	0,2	neutral	2,19	neutral	-1,62	deleterious	-5,32	medium_impact	3,06	neutral	0,67	damaging	0,02	deleterious	3,31	22,9	0,07	0,35	neutral	0,39	disease	0,73	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,8	low_impact	-2,81	medium_impact	-0,15	medium_impact	1,56	0,22	0,8	73,56	11,66	N	0,39	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9410	9410	A	T	MI.7063	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	204	68	Q	H	caA/caT	5,45	1	0,01	probably_damaging	1	neutral	0,54	neutral	2,21	neutral	-1,32	deleterious	-4,45	medium_impact	2,99	neutral	0,61	damaging	0,02	deleterious	3,48	23,1	0,33	0,5	neutral	0,21	disease	0,52	disease	0,53	disease	0,51	0	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,74	low_impact	-3,78	medium_impact	0,23	medium_impact	1,5	0,26	0,8	73,56	11,66	N	0,4	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9410	9410	A	C	MI.7064	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	204	68	Q	H	caA/caC	5,45	1	0,01	probably_damaging	1	neutral	0,54	neutral	2,21	neutral	-1,32	deleterious	-4,45	medium_impact	2,99	neutral	0,61	damaging	0,02	deleterious	3,36	22,9	0,33	0,5	neutral	0,21	disease	0,52	disease	0,53	disease	0,51	0	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,74	low_impact	-3,78	medium_impact	0,23	medium_impact	1,5	0,26	0,8	73,56	11,66	N	0,39	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9411	9411	G	A	MI.7065	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	205	69	G	S	Ggc/Agc	1,29	1	0	probably_damaging	1	neutral	0,4	neutral	0,94	deleterious	-5,26	deleterious	-5,62	high_impact	4,27	damaging	0,57	damaging	0,02	deleterious	4,16	23,8	0,17	0,45	neutral	0,18	disease	0,76	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	0,09	high_impact	2,64	0,5	0,8	74,33	11,61	N	0,41	N	0,85	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9411	9411	G	C	MI.7066	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	205	69	G	R	Ggc/Cgc	1,29	1	0	probably_damaging	1	neutral	0,33	neutral	0,9	deleterious	-6,58	deleterious	-7,51	medium_impact	3,46	neutral	0,63	damaging	0,02	deleterious	3,9	23,5	0,09	0,35	neutral	0,25	disease	0,77	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,8	low_impact	-3,78	medium_impact	0,02	medium_impact	1,92	0,55	0,8	74,33	11,61	N	0,34	N	0,99	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9411	9411	G	T	MI.7067	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	205	69	G	C	Ggc/Tgc	1,29	1	0	probably_damaging	1	neutral	0,18	neutral	0,89	deleterious	-7,58	deleterious	-8,45	high_impact	4,62	damaging	0,56	damaging	0,02	deleterious	4,06	23,7	0,07	0,35	disease	0,7	disease	0,82	disease	0,74	disease	0,76	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,18	high_impact	2,96	0,08	0,8	74,33	11,61	N	0,47	N	0,98	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9412	9412	G	C	MI.7068	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	206	69	G	A	gGc/gCc	6,14	1	0	probably_damaging	1	neutral	0,5	neutral	0,95	deleterious	-4,99	deleterious	-5,63	high_impact	4,07	damaging	0,57	damaging	0,01	deleterious	3,03	22,3	0,23	0,45	neutral	0,19	disease	0,62	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,75	low_impact	-3,78	medium_impact	0,19	high_impact	2,47	0,21	0,8	74,33	11,61	N	0,46	N	0,3	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9412	9412	G	A	MI.7069	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	206	69	G	D	gGc/gAc	6,14	1	0	probably_damaging	1	neutral	0,2	neutral	0,91	deleterious	-6,07	deleterious	-6,57	medium_impact	3,15	damaging	0,49	damaging	0,02	deleterious	3,83	23,4	0,08	0,35	neutral	0,25	disease	0,81	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,78	low_impact	-3,78	medium_impact	-0,15	medium_impact	1,64	0,07	0,8	74,33	11,61	N	0,44	N	0,98	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8860	8860	A	T	MI.707	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	334	112	T	S	Aca/Tca	-9,59	0	0,24	benign	0,07	neutral	0,4	neutral	4,21	neutral	-1,87	deleterious	-3,36	medium_impact	2,32	neutral	0,64	neutral	0,61	neutral	1,39	12,76	0,39	0,65	neutral	0,34	disease	0,78	disease	0,63	disease	0,61	2	neutral	0,55	deleterious	0,67	neutral	-3	neutral	0,22	medium_impact	0,31	medium_impact	0,19	medium_impact	0,89	0,72	0,9	5,75	12,69	N	0,34	N	0,38	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9412	9412	G	T	MI.7070	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	206	69	G	V	gGc/gTc	6,14	1	0	probably_damaging	1	neutral	0,48	neutral	0,9	deleterious	-6,37	deleterious	-8,45	high_impact	4,27	damaging	0,52	damaging	0,01	deleterious	3,7	23,3	0,06	0,35	neutral	0,36	disease	0,82	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	0,17	high_impact	2,64	0,03	0,8	74,33	11,61	N	0,46	N	0,97	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9414	9414	C	G	MI.7071	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	208	70	H	D	Cac/Gac	-12,6	0	0	probably_damaging	0,98	neutral	0,2	neutral	2,55	neutral	-0,15	deleterious	-4,99	low_impact	1,53	damaging	0,49	damaging	0,05	deleterious	3,77	23,4	0,2	0,45	neutral	0,21	neutral	0,37	disease	0,59	neutral	0,46	1	deleterious	0,99	neutral	0,11	neutral	-2	deleterious	0,69	low_impact	-2,51	medium_impact	-0,15	medium_impact	0,19	0,33	0,8	73,95	11,47	N	0,3	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9414	9414	C	A	MI.7072	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	208	70	H	N	Cac/Aac	-12,6	0	0	probably_damaging	0,98	neutral	0,31	neutral	2,51	neutral	-0,81	deleterious	-3,45	medium_impact	1,98	damaging	0,54	damaging	0,09	deleterious	3,79	23,4	0,5	0,6	neutral	0,26	neutral	0,38	neutral	0,43	neutral	0,44	1	neutral	0,98	neutral	0,17	deleterious	1	deleterious	0,68	low_impact	-2,51	medium_impact	-0,01	medium_impact	0,59	0,2	0,8	73,95	11,47	N	0,28	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9414	9414	C	T	MI.7073	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	208	70	H	Y	Cac/Tac	-12,6	0	0	probably_damaging	0,96	neutral	1	neutral	2,53	neutral	-1,88	deleterious	-2,81	low_impact	1,25	damaging	0,5	damaging	0,06	deleterious	2,64	20,5	0,28	0,45	neutral	0,36	neutral	0,42	neutral	0,32	neutral	0,47	1	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,72	low_impact	-2,21	high_impact	1,9	medium_impact	-0,06	0,13	0,8	73,95	11,47	N	0,2	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9415	9415	A	C	MI.7074	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	209	70	H	P	cAc/cCc	5,45	1	0	probably_damaging	0,99	neutral	0,2	neutral	2,53	neutral	-2,13	deleterious	-5,53	medium_impact	3,2	damaging	0,45	damaging	0,03	deleterious	3,63	23,2	0,09	0,35	neutral	0,43	disease	0,72	disease	0,54	disease	0,68	4	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,81	low_impact	-2,81	medium_impact	-0,15	medium_impact	1,69	0,13	0,8	73,95	11,47	N	0,46	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9415	9415	A	T	MI.7075	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	209	70	H	L	cAc/cTc	5,45	1	0	probably_damaging	0,97	neutral	0,68	neutral	2,63	neutral	-0,34	deleterious	-4,77	low_impact	1,32	damaging	0,55	damaging	0,08	deleterious	2,9	21,9	0,18	0,45	neutral	0,25	neutral	0,27	neutral	0,37	neutral	0,43	2	neutral	0,96	neutral	0,36	neutral	-2	deleterious	0,68	low_impact	-2,34	medium_impact	0,38	medium_impact	0	0,1	0,8	73,95	11,47	N	0,39	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9415	9415	A	G	MI.7076	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	209	70	H	R	cAc/cGc	5,45	1	0	probably_damaging	0,97	neutral	0,35	neutral	2,53	neutral	-0,59	deleterious	-3,98	medium_impact	2,58	damaging	0,48	damaging	0,05	deleterious	3,4	23	0,22	0,45	neutral	0,25	neutral	0,41	neutral	0,49	neutral	0,45	1	neutral	0,97	neutral	0,19	deleterious	1	deleterious	0,7	low_impact	-2,34	medium_impact	0,04	medium_impact	1,13	0,11	0,8	73,95	11,47	N	0,48	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9416	9416	C	A	MI.7077	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	210	70	H	Q	caC/caA	8,69	1	0	probably_damaging	0,98	neutral	0,34	neutral	2,53	neutral	-0,49	deleterious	-3,93	low_impact	1,37	damaging	0,54	damaging	0,05	deleterious	3,82	23,4	0,35	0,5	neutral	0,23	neutral	0,34	neutral	0,4	neutral	0,44	1	deleterious	0,98	neutral	0,18	neutral	-2	deleterious	0,69	low_impact	-2,51	medium_impact	0,03	medium_impact	0,05	0,25	0,8	73,95	11,47	P	0,5	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9416	9416	C	G	MI.7078	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	210	70	H	Q	caC/caG	8,69	1	0	probably_damaging	0,98	neutral	0,34	neutral	2,53	neutral	-0,49	deleterious	-3,93	low_impact	1,37	damaging	0,54	damaging	0,05	deleterious	3,48	23,1	0,35	0,5	neutral	0,23	neutral	0,34	neutral	0,4	neutral	0,44	1	deleterious	0,98	neutral	0,18	neutral	-2	deleterious	0,69	low_impact	-2,51	medium_impact	0,03	medium_impact	0,05	0,25	0,8	73,95	11,47	P	0,5	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9417	9417	C	T	MI.7079	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	211	71	H	Y	Cac/Tac	-1,03	0,01	0	probably_damaging	0,99	neutral	1	neutral	1,45	deleterious	-4,71	deleterious	-5,64	medium_impact	2,6	damaging	0,59	damaging	0,02	deleterious	3,62	23,2	0,38	0,5	neutral	0,46	disease	0,75	disease	0,74	disease	0,72	4	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,8	low_impact	-2,81	high_impact	1,9	medium_impact	1,15	0,13	0,8	74,71	11,46	N	0,21	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8860	8860	A	G	MI.708	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	334	112	T	A	Aca/Gca	-9,59	0	0,24	benign	0	neutral	0,61	neutral	4,23	neutral	-0,73	deleterious	-3,97	medium_impact	2,15	neutral	0,96	neutral	0,91	deleterious	0,35	6,13	0,47	0,65	neutral	0,33	disease	0,7	disease	0,61	disease	0,52	0	neutral	0,38	deleterious	0,81	neutral	-3	neutral	0,14	high_impact	2,09	medium_impact	0,4	medium_impact	0,75	0,43	0,9	5,75	12,69	N	0,27	N	0	polymorphism	1	0,07	rs2001031	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9417	9417	C	G	MI.7080	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	211	71	H	D	Cac/Gac	-1,03	0,01	0	probably_damaging	1	neutral	0,21	neutral	1,45	deleterious	-4,66	deleterious	-8,47	high_impact	4,22	damaging	0,58	damaging	0,02	deleterious	3,77	23,4	0,13	0,4	neutral	0,2	disease	0,74	disease	0,81	disease	0,75	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,75	low_impact	-3,78	medium_impact	-0,14	high_impact	2,6	0,24	0,8	74,71	11,46	N	0,39	N	0,98	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9417	9417	C	A	MI.7081	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	211	71	H	N	Cac/Aac	-1,03	0,01	0	probably_damaging	0,99	neutral	0,31	neutral	1,44	deleterious	-4,93	deleterious	-6,58	medium_impact	3,25	damaging	0,58	damaging	0,02	deleterious	3,94	23,5	0,43	0,55	neutral	0,23	disease	0,73	disease	0,78	disease	0,73	5	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,76	low_impact	-2,81	medium_impact	-0,01	medium_impact	1,73	0,14	0,8	74,71	11,46	N	0,32	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9418	9418	A	T	MI.7082	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	212	71	H	L	cAc/cTc	7,3	1	0	probably_damaging	0,99	neutral	0,67	neutral	1,44	deleterious	-4,8	deleterious	-10,35	high_impact	3,76	damaging	0,56	damaging	0,02	deleterious	3,84	23,4	0,12	0,4	neutral	0,3	disease	0,76	disease	0,78	disease	0,74	5	deleterious	0,99	neutral	0,34	deleterious	2	deleterious	0,77	low_impact	-2,81	medium_impact	0,37	high_impact	2,19	0,09	0,8	74,71	11,46	N	0,48	N	0,96	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9418	9418	A	C	MI.7083	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	212	71	H	P	cAc/cCc	7,3	1	0	probably_damaging	1	neutral	0,21	neutral	1,42	deleterious	-5,91	deleterious	-9,41	high_impact	3,52	damaging	0,58	damaging	0,03	deleterious	3,15	22,6	0,06	0,35	neutral	0,32	disease	0,78	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,14	medium_impact	1,97	0,09	0,8	74,71	11,46	N	0,44	N	0,98	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9418	9418	A	G	MI.7084	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	212	71	H	R	cAc/cGc	7,3	1	0	probably_damaging	0,99	neutral	0,35	neutral	1,46	deleterious	-4,47	deleterious	-7,53	high_impact	3,6	neutral	0,66	damaging	0,02	deleterious	2,95	22,1	0,23	0,45	neutral	0,23	disease	0,7	disease	0,77	disease	0,73	5	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,77	low_impact	-2,81	medium_impact	0,04	high_impact	2,04	0,12	0,8	74,71	11,46	N	0,49	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9419	9419	C	G	MI.7085	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	213	71	H	Q	caC/caG	7,07	1	0	probably_damaging	1	neutral	0,3	neutral	1,44	deleterious	-4,89	deleterious	-7,53	medium_impact	3,37	neutral	0,62	damaging	0,02	deleterious	3,48	23,1	0,3	0,45	neutral	0,16	disease	0,73	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	-0,02	medium_impact	1,84	0,19	0,8	74,71	11,46	N	0,45	N	0,94	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9419	9419	C	A	MI.7086	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	213	71	H	Q	caC/caA	7,07	1	0	probably_damaging	1	neutral	0,3	neutral	1,44	deleterious	-4,89	deleterious	-7,53	medium_impact	3,37	neutral	0,62	damaging	0,02	deleterious	3,81	23,4	0,3	0,45	neutral	0,16	disease	0,73	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	-0,02	medium_impact	1,84	0,19	0,8	74,71	11,46	N	0,46	N	0,94	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9420	9420	A	G	MI.7087	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	214	72	T	A	Aca/Gca	-2,42	0	0	probably_damaging	0,95	neutral	0,52	neutral	2	neutral	-1,94	deleterious	-4,7	medium_impact	3,12	neutral	0,65	damaging	0,05	neutral	1,56	13,63	0,36	0,5	neutral	0,19	neutral	0,47	disease	0,65	neutral	0,48	0	neutral	0,95	neutral	0,29	deleterious	1	deleterious	0,68	low_impact	-2,11	medium_impact	0,21	medium_impact	1,61	0,19	0,8	74,33	11,62	N	0,27	N	0,44	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9420	9420	A	C	MI.7088	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	214	72	T	P	Aca/Cca	-2,42	0	0	probably_damaging	0,99	neutral	0,21	neutral	1,9	deleterious	-4,02	deleterious	-5,64	high_impact	3,9	neutral	0,63	damaging	0,05	deleterious	3,35	22,9	0,08	0,35	neutral	0,44	disease	0,65	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,78	low_impact	-2,81	medium_impact	-0,14	high_impact	2,31	0,15	0,8	74,33	11,62	N	0,3	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9420	9420	A	T	MI.7089	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	214	72	T	S	Aca/Tca	-2,42	0	0	probably_damaging	0,95	neutral	0,42	neutral	2,01	neutral	-1,84	deleterious	-3,75	low_impact	1,58	damaging	0,48	damaging	0,11	neutral	1,21	11,78	0,47	0,55	neutral	0,16	neutral	0,36	neutral	0,31	neutral	0,39	2	neutral	0,95	neutral	0,24	neutral	-2	deleterious	0,69	low_impact	-2,11	medium_impact	0,11	medium_impact	0,23	0,27	0,8	74,33	11,62	N	0,31	N	0,77	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8860	8860	A	C	MI.709	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	334	112	T	P	Aca/Cca	-9,59	0	0,24	benign	0,28	neutral	0,22	neutral	4,17	deleterious	-3,73	deleterious	-5,25	medium_impact	3,08	damaging	0,52	neutral	0,44	deleterious	1,81	15,05	0,11	0,65	disease	0,8	disease	0,92	disease	0,76	disease	0,78	6	neutral	0,74	deleterious	0,47	neutral	-3	deleterious	0,54	medium_impact	-0,37	medium_impact	-0,02	medium_impact	1,54	0,6	0,9	5,75	12,69	N	0,35	N	0,79	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9421	9421	C	T	MI.7090	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	215	72	T	M	aCa/aTa	6,84	1	0	probably_damaging	1	neutral	0,23	neutral	1,89	deleterious	-4,51	deleterious	-5,64	high_impact	4,45	neutral	0,68	damaging	0,01	deleterious	3,98	23,6	0,18	0,45	neutral	0,48	disease	0,6	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,74	low_impact	-3,78	medium_impact	-0,11	high_impact	2,81	0,26	0,8	74,33	11,62	P	0,54	P	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9421	9421	C	A	MI.7091	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	215	72	T	K	aCa/aAa	6,84	1	0	probably_damaging	0,99	neutral	0,32	neutral	1,95	neutral	-2,7	deleterious	-5,63	high_impact	3,75	neutral	0,69	damaging	0,02	deleterious	4,09	23,7	0,11	0,4	neutral	0,16	disease	0,66	disease	0,7	disease	0,69	4	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,73	low_impact	-2,81	medium_impact	0,01	high_impact	2,18	0,1	0,8	74,33	11,62	N	0,5	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9423	9423	C	G	MI.7092	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	217	73	P	A	Cca/Gca	-12,6	0	0	benign	0	neutral	0,72	neutral	2,62	neutral	0,49	neutral	-0,18	neutral_impact	0,76	neutral	0,69	neutral	0,6	neutral	-0,3	0,66	0,31	0,5	neutral	0,1	neutral	0,13	neutral	0,25	neutral	0,27	5	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	0,43	medium_impact	-0,5	0,38	0,8	19,54	40,68	N	0,38	N	0,49	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9423	9423	C	T	MI.7093	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	217	73	P	S	Cca/Tca	-12,6	0	0	benign	0,01	neutral	0,67	neutral	2,62	neutral	0,1	neutral	0,41	neutral_impact	-0,18	neutral	0,77	neutral	0,84	deleterious	0,26	5,29	0,35	0,5	neutral	0,09	neutral	0,12	neutral	0,12	neutral	0,29	4	neutral	0,32	deleterious	0,83	neutral	-6	neutral	0,09	medium_impact	1,07	medium_impact	0,37	low_impact	-1,34	0,28	0,8	19,54	40,68	N	0,43	N	0,51	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9423	9423	C	A	MI.7094	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	217	73	P	T	Cca/Aca	-12,6	0	0	benign	0	neutral	0,76	neutral	2,62	neutral	-0,04	neutral	-0,07	neutral_impact	0,68	neutral	0,7	neutral	0,78	deleterious	0,14	4,07	0,27	0,45	neutral	0,09	neutral	0,17	neutral	0,13	neutral	0,3	4	neutral	0,24	deleterious	0,88	neutral	-6	neutral	0,08	high_impact	2,05	medium_impact	0,48	medium_impact	-0,57	0,27	0,8	19,54	40,68	N	0,47	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9424	9424	C	T	MI.7095	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	218	73	P	L	cCa/cTa	-0,1	0	0	benign	0	neutral	0,74	neutral	2,67	neutral	-0,68	neutral	-0,95	neutral_impact	0,27	neutral	0,75	neutral	0,89	deleterious	0,53	7,64	0,19	0,45	neutral	0,11	neutral	0,16	neutral	0,15	neutral	0,27	5	neutral	0,26	deleterious	0,87	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	0,45	medium_impact	-0,94	0,64	0,8	19,54	40,68	N	0,44	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9424	9424	C	A	MI.7096	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	218	73	P	Q	cCa/cAa	-0,1	0	0	benign	0,04	neutral	0,44	neutral	2,56	neutral	-0,1	neutral	-0,49	low_impact	1,6	neutral	0,7	neutral	0,54	neutral	0,9	10,07	0,24	0,45	neutral	0,12	neutral	0,22	neutral	0,32	neutral	0,4	2	neutral	0,52	deleterious	0,7	neutral	-6	neutral	0,12	medium_impact	0,47	medium_impact	0,13	medium_impact	0,25	0,18	0,8	19,54	40,68	N	0,41	N	0,61	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9424	9424	C	G	MI.7097	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	218	73	P	R	cCa/cGa	-0,1	0	0	benign	0,03	neutral	0,47	neutral	2,58	neutral	0,39	neutral	-0,89	low_impact	1,14	neutral	0,62	neutral	0,4	deleterious	0,38	6,46	0,16	0,45	neutral	0,13	neutral	0,27	neutral	0,41	neutral	0,42	2	neutral	0,5	deleterious	0,72	neutral	-6	neutral	0,13	medium_impact	0,6	medium_impact	0,16	medium_impact	-0,16	0,25	0,8	19,54	40,68	N	0,38	N	0,8	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9426	9426	C	G	MI.7098	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	220	74	P	A	Cct/Gct	-12,83	0	0	benign	0,13	neutral	0,58	neutral	2,46	neutral	1,27	neutral	-0,7	neutral_impact	-0,18	neutral	0,69	neutral	0,91	deleterious	0,09	3,53	0,35	0,5	neutral	0,11	neutral	0,14	neutral	0,32	neutral	0,26	5	neutral	0,32	deleterious	0,73	neutral	-6	neutral	0,14	medium_impact	-0,07	medium_impact	0,27	low_impact	-1,34	0,53	0,8	16,86	35,62	N	0,43	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9426	9426	C	T	MI.7099	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	220	74	P	S	Cct/Tct	-12,83	0	0	benign	0,02	neutral	0,5	neutral	2,37	neutral	1,02	neutral	-0,96	neutral_impact	0,7	neutral	0,74	neutral	0,53	deleterious	0,63	8,37	0,37	0,5	neutral	0,11	neutral	0,21	neutral	0,3	neutral	0,35	3	neutral	0,47	deleterious	0,74	neutral	-6	neutral	0,1	medium_impact	0,77	medium_impact	0,19	medium_impact	-0,56	0,24	0,8	16,86	35,62	N	0,39	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8557	8557	G	C	MI.71	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	31	11	A	P	Gcc/Ccc	-0,8	0	0,02	possibly_damaging	0,56	neutral	1	neutral	4,71	neutral	-1,53	neutral	-1,8	neutral_impact	-0,55	neutral	0,81	neutral	0,57	deleterious	3,2	22,7	0,27	0,65	neutral	0,46	disease	0,73	neutral	0,22	neutral	0,48	0	neutral	0,56	deleterious	0,72	neutral	-3	deleterious	0,64	medium_impact	-0,86	high_impact	1,98	low_impact	-1,57	0,62	0,9	23,45	19,76	N	0,19	N	0,75	polymorphism	1	0,03	rs386829040	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8861	8861	C	T	MI.710	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	335	112	T	M	aCa/aTa	0,59	0,04	0	possibly_damaging	0,64	neutral	0,25	neutral	4,22	neutral	-1,94	deleterious	-5,24	medium_impact	2,5	neutral	0,69	neutral	0,56	deleterious	3,65	23,2	0,29	0,65	disease	0,61	disease	0,83	disease	0,59	disease	0,61	2	neutral	0,78	neutral	0,31	NA	0	deleterious	0,55	medium_impact	-0,99	medium_impact	0,02	medium_impact	1,05	0,77	0,9	5,75	12,69	N	0,34	N	0,82	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9426	9426	C	A	MI.7100	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	220	74	P	T	Cct/Act	-12,83	0	0	benign	0,3	neutral	0,5	neutral	2,4	neutral	0,85	neutral	-0,79	neutral_impact	0,14	neutral	0,75	neutral	0,96	deleterious	1,94	15,81	0,26	0,45	neutral	0,12	neutral	0,22	neutral	0,31	neutral	0,38	2	neutral	0,4	deleterious	0,6	neutral	-6	neutral	0,19	medium_impact	-0,51	medium_impact	0,19	low_impact	-1,06	0,36	0,8	16,86	35,62	N	0,4	N	0,3	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9427	9427	C	G	MI.7101	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	221	74	P	R	cCt/cGt	-0,33	0	0	possibly_damaging	0,69	neutral	0,4	neutral	2,34	neutral	1,2	neutral	-1,5	neutral_impact	0,12	neutral	0,63	damaging	0,22	deleterious	2,26	17,88	0,16	0,45	neutral	0,14	neutral	0,4	neutral	0,44	neutral	0,44	1	neutral	0,71	neutral	0,36	neutral	-3	neutral	0,42	low_impact	-1,21	medium_impact	0,09	low_impact	-1,08	0,36	0,8	16,86	35,62	N	0,28	N	0,69	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9427	9427	C	T	MI.7102	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	221	74	P	L	cCt/cTt	-0,33	0	0	benign	0,42	neutral	0,7	neutral	2,44	neutral	0,31	neutral	-0,72	neutral_impact	0,35	neutral	0,71	neutral	0,31	deleterious	2,69	20,8	0,2	0,45	neutral	0,09	neutral	0,27	neutral	0,32	neutral	0,41	2	neutral	0,32	deleterious	0,64	neutral	-6	neutral	0,26	medium_impact	-0,73	medium_impact	0,4	medium_impact	-0,87	0,54	0,8	16,86	35,62	N	0,26	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9427	9427	C	A	MI.7103	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	221	74	P	H	cCt/cAt	-0,33	0	0	possibly_damaging	0,86	neutral	0,56	neutral	2,32	neutral	-0,47	neutral	-1,93	low_impact	1,07	neutral	0,69	damaging	0,24	deleterious	2,84	21,6	0,23	0,45	neutral	0,24	neutral	0,31	neutral	0,26	neutral	0,45	1	neutral	0,84	neutral	0,35	neutral	-3	deleterious	0,57	low_impact	-1,64	medium_impact	0,25	medium_impact	-0,22	0,28	0,8	16,86	35,62	N	0,28	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9429	9429	G	A	MI.7104	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	223	75	V	I	Gtc/Atc	-9,13	0	0	probably_damaging	0,93	neutral	0,49	neutral	1,84	neutral	-1,68	neutral	-0,93	medium_impact	3	damaging	0,52	neutral	0,63	deleterious	3,57	23,1	0,43	0,55	neutral	0,3	neutral	0,5	disease	0,59	neutral	0,47	1	neutral	0,92	neutral	0,28	deleterious	1	deleterious	0,69	low_impact	-1,96	medium_impact	0,18	medium_impact	1,51	0,66	0,8	73,56	11,46	N	0,45	N	0,21	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9429	9429	G	C	MI.7105	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	223	75	V	L	Gtc/Ctc	-9,13	0	0	probably_damaging	0,93	neutral	0,72	neutral	1,73	neutral	-2,44	deleterious	-2,77	medium_impact	2,88	damaging	0,55	neutral	0,55	deleterious	3,57	23,1	0,29	0,45	neutral	0,25	disease	0,7	disease	0,56	disease	0,59	2	neutral	0,92	neutral	0,4	deleterious	1	deleterious	0,73	low_impact	-1,96	medium_impact	0,43	medium_impact	1,4	0,43	0,8	73,56	11,46	N	0,3	N	0,68	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9429	9429	G	T	MI.7106	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	223	75	V	F	Gtc/Ttc	-9,13	0	0	probably_damaging	1	neutral	0,54	neutral	1,6	deleterious	-4,67	deleterious	-4,63	high_impact	4,53	damaging	0,52	neutral	0,5	deleterious	3,83	23,4	0,12	0,4	neutral	0,44	disease	0,88	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	0,23	high_impact	2,88	0,14	0,8	73,56	11,46	N	0,5	N	0,94	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9430	9430	T	A	MI.7107	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	224	75	V	D	gTc/gAc	7,53	1	0	probably_damaging	1	neutral	0,62	neutral	1,57	deleterious	-6,24	deleterious	-6,42	high_impact	4,18	damaging	0,6	neutral	0,5	deleterious	4,4	24,1	0,04	0,35	neutral	0,29	disease	0,88	disease	0,78	disease	0,76	5	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	0,31	high_impact	2,56	0,05	0,8	73,56	11,46	P	0,56	P	0,94	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9430	9430	T	C	MI.7108	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	224	75	V	A	gTc/gCc	7,53	1	0	probably_damaging	0,99	neutral	0,85	neutral	1,63	deleterious	-3,84	deleterious	-3,67	high_impact	3,63	damaging	0,58	neutral	0,65	deleterious	3,49	23,1	0,28	0,45	neutral	0,21	disease	0,66	disease	0,66	disease	0,66	3	deleterious	0,99	neutral	0,43	deleterious	2	deleterious	0,75	low_impact	-2,81	medium_impact	0,62	high_impact	2,07	0,2	0,8	73,56	11,46	N	0,53	P	0,39	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9430	9430	T	G	MI.7109	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	224	75	V	G	gTc/gGc	7,53	1	0	probably_damaging	1	neutral	0,58	neutral	1,58	deleterious	-5,67	deleterious	-6,44	high_impact	3,56	damaging	0,57	neutral	0,61	deleterious	3,75	23,3	0,06	0,35	neutral	0,36	disease	0,76	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	0,27	high_impact	2,01	0,17	0,8	73,56	11,46	N	0,48	N	0,88	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8861	8861	C	A	MI.711	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	335	112	T	K	aCa/aAa	0,59	0,04	0	benign	0,11	neutral	0,29	neutral	4,18	deleterious	-3,05	deleterious	-5,24	high_impact	3,54	neutral	0,61	neutral	0,45	deleterious	2,56	19,82	0,13	0,65	disease	0,73	disease	0,93	disease	0,75	disease	0,79	6	neutral	0,67	deleterious	0,59	neutral	-2	neutral	0,4	medium_impact	0,11	medium_impact	0,07	medium_impact	1,94	0,75	0,9	5,75	12,69	N	0,4	N	0,78	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9432	9432	C	G	MI.7110	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	226	76	Q	E	Caa/Gaa	-13,75	0	0	probably_damaging	0,91	neutral	0,32	neutral	2,29	neutral	0,01	neutral	-1,12	low_impact	1,38	damaging	0,5	damaging	0,07	deleterious	3,04	22,3	0,42	0,55	neutral	0,13	disease	0,69	neutral	0,31	disease	0,53	1	neutral	0,92	neutral	0,21	neutral	-2	deleterious	0,69	low_impact	-1,85	medium_impact	0,01	medium_impact	0,05	0,34	0,8	73,95	11,67	N	0,27	N	0,95	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9432	9432	C	A	MI.7111	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	226	76	Q	K	Caa/Aaa	-13,75	0	0	probably_damaging	0,96	neutral	0,35	neutral	2,3	neutral	0	neutral	-1,65	low_impact	1,61	damaging	0,49	damaging	0,11	deleterious	3,88	23,5	0,39	0,5	neutral	0,15	disease	0,69	neutral	0,31	neutral	0,48	0	neutral	0,96	neutral	0,2	neutral	-2	deleterious	0,7	low_impact	-2,21	medium_impact	0,04	medium_impact	0,26	0,33	0,8	73,95	11,67	N	0,3	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9433	9433	A	T	MI.7112	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	227	76	Q	L	cAa/cTa	7,3	1	0	probably_damaging	0,96	neutral	0,67	neutral	2,24	neutral	-1,71	deleterious	-2,56	low_impact	1,75	damaging	0,48	damaging	0,09	deleterious	3,75	23,3	0,14	0,4	neutral	0,29	disease	0,76	neutral	0,39	disease	0,53	1	neutral	0,95	neutral	0,36	neutral	-2	deleterious	0,75	low_impact	-2,21	medium_impact	0,37	medium_impact	0,39	0,12	0,8	73,95	11,67	N	0,46	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9433	9433	A	C	MI.7113	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	227	76	Q	P	cAa/cCa	7,3	1	0	probably_damaging	0,99	neutral	0,22	neutral	2,19	neutral	-2,1	deleterious	-2,79	low_impact	1,78	damaging	0,45	damaging	0,04	deleterious	3,3	22,9	0,18	0,45	neutral	0,25	disease	0,89	disease	0,61	disease	0,75	5	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,81	low_impact	-2,81	medium_impact	-0,12	medium_impact	0,41	0,18	0,8	73,95	11,67	N	0,45	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9433	9433	A	G	MI.7114	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	227	76	Q	R	cAa/cGa	7,3	1	0	probably_damaging	0,97	neutral	0,38	neutral	2,26	neutral	-0,62	neutral	-1,87	low_impact	1,88	damaging	0,47	damaging	0,06	deleterious	3,41	23	0,48	0,55	neutral	0,16	disease	0,69	neutral	0,48	neutral	0,49	0	neutral	0,97	neutral	0,21	neutral	-2	deleterious	0,74	low_impact	-2,34	medium_impact	0,07	medium_impact	0,5	0,12	0,8	73,95	11,67	P	0,52	P	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9434	9434	A	C	MI.7115	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	228	76	Q	H	caA/caC	6,84	1	0	probably_damaging	0,99	neutral	0,55	neutral	2,2	neutral	-2,01	deleterious	-2,5	medium_impact	2,68	damaging	0,56	damaging	0,04	deleterious	3,25	22,8	0,34	0,5	neutral	0,34	disease	0,68	neutral	0,34	disease	0,53	1	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,76	low_impact	-2,81	medium_impact	0,24	medium_impact	1,22	0,34	0,8	73,95	11,67	N	0,42	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9434	9434	A	T	MI.7116	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	228	76	Q	H	caA/caT	6,84	1	0	probably_damaging	0,99	neutral	0,55	neutral	2,2	neutral	-2,01	deleterious	-2,5	medium_impact	2,68	damaging	0,56	damaging	0,04	deleterious	3,46	23	0,34	0,5	neutral	0,34	disease	0,68	neutral	0,34	disease	0,53	1	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,76	low_impact	-2,81	medium_impact	0,24	medium_impact	1,22	0,34	0,8	73,95	11,67	N	0,44	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9435	9435	A	G	MI.7117	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	229	77	K	E	Aaa/Gaa	4,76	1	0	probably_damaging	0,94	neutral	0,3	neutral	2,23	neutral	-0,71	neutral	-2,16	medium_impact	2,2	neutral	0,67	neutral	0,59	deleterious	3,67	23,3	0,28	0,45	neutral	0,19	disease	0,74	neutral	0,46	disease	0,52	0	neutral	0,95	neutral	0,18	deleterious	1	deleterious	0,69	low_impact	-2,03	medium_impact	-0,02	medium_impact	0,79	0,44	0,8	75,1	11,08	P	0,56	P	0,95	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9435	9435	A	C	MI.7118	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	229	77	K	Q	Aaa/Caa	4,76	1	0	probably_damaging	0,93	neutral	0,31	neutral	2,18	neutral	-1,27	neutral	-2,06	low_impact	1,6	neutral	0,66	neutral	0,33	deleterious	3,12	22,6	0,55	0,6	neutral	0,24	disease	0,51	neutral	0,26	neutral	0,43	1	neutral	0,94	neutral	0,19	neutral	-2	deleterious	0,65	low_impact	-1,96	medium_impact	-0,01	medium_impact	0,25	0,28	0,8	75,1	11,08	P	0,52	P	0,92	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9436	9436	A	C	MI.7119	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	230	77	K	T	aAa/aCa	4,76	1	0	probably_damaging	0,98	neutral	0,41	neutral	2,16	neutral	-1,59	deleterious	-2,61	low_impact	1,34	neutral	0,69	damaging	0,27	deleterious	2,31	18,2	0,23	0,45	neutral	0,27	disease	0,55	neutral	0,28	neutral	0,44	1	neutral	0,98	neutral	0,22	neutral	-2	deleterious	0,69	low_impact	-2,51	medium_impact	0,1	medium_impact	0,02	0,14	0,8	75,1	11,08	N	0,46	N	0,87	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8863	8863	G	C	MI.712	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	337	113	V	L	Gtg/Ctg	-8,43	0	0	probably_damaging	0,98	neutral	0,52	neutral	4,5	neutral	0,72	neutral	-2,46	low_impact	1,42	neutral	0,75	neutral	0,58	deleterious	3,57	23,1	0,4	0,65	neutral	0,33	disease	0,7	neutral	0,41	neutral	0,42	2	neutral	0,98	neutral	0,27	neutral	-2	deleterious	0,72	low_impact	-2,36	medium_impact	0,31	medium_impact	0,12	0,75	0,9	42,04	7,9	N	0,28	N	0,7	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9436	9436	A	T	MI.7120	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	230	77	K	M	aAa/aTa	4,76	1	0	probably_damaging	0,99	neutral	0,23	neutral	2,1	deleterious	-3,37	deleterious	-2,93	low_impact	1,14	neutral	0,73	damaging	0,26	deleterious	3,59	23,2	0,2	0,45	disease	0,53	neutral	0,48	neutral	0,28	disease	0,51	0	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,72	low_impact	-2,81	medium_impact	-0,11	medium_impact	-0,16	0,15	0,8	75,1	11,08	N	0,47	N	0,72	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9437	9437	A	C	MI.7121	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	231	77	K	N	aaA/aaC	8,69	1	0	probably_damaging	0,99	neutral	0,32	neutral	2,18	neutral	-1,34	neutral	-1,98	low_impact	1,38	neutral	0,66	damaging	0,22	deleterious	2,62	20,3	0,63	0,65	neutral	0,24	disease	0,51	neutral	0,29	neutral	0,44	1	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,7	low_impact	-2,81	medium_impact	0,01	medium_impact	0,05	0,3	0,8	75,1	11,08	P	0,53	P	0,94	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9437	9437	A	T	MI.7122	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	231	77	K	N	aaA/aaT	8,69	1	0	probably_damaging	0,99	neutral	0,32	neutral	2,18	neutral	-1,34	neutral	-1,98	low_impact	1,38	neutral	0,66	damaging	0,22	deleterious	2,8	21,3	0,63	0,65	neutral	0,24	disease	0,51	neutral	0,29	neutral	0,44	1	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,7	low_impact	-2,81	medium_impact	0,01	medium_impact	0,05	0,3	0,8	75,1	11,08	P	0,57	P	0,94	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9438	9438	G	A	MI.7123	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	232	78	G	S	Ggc/Agc	0,36	0,98	0	benign	0,1	neutral	0,41	neutral	2,03	neutral	-1,72	deleterious	-4,27	medium_impact	2,14	damaging	0,22	neutral	0,59	deleterious	2,33	18,37	0,23	0,45	neutral	0,18	disease	0,82	disease	0,68	disease	0,53	1	neutral	0,53	deleterious	0,66	neutral	-3	neutral	0,27	medium_impact	0,06	medium_impact	0,1	medium_impact	0,74	0,46	0,8	30,65	18,16	P	0,93	P	0,34	disease_causing_automatic	0	0,11	rs267606611	Pathogenic	Leber's_optic_atrophy	RCV000010286.2	MedGen:OMIM:SNOMED_CT	.	.	.	2,97	G9438A	LHON	+	-	Conflicting reports	13
chrM	9438	9438	G	C	MI.7124	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	232	78	G	R	Ggc/Cgc	0,36	0,98	0	probably_damaging	0,98	neutral	0,36	neutral	1,93	deleterious	-3,41	deleterious	-6,15	high_impact	3,69	neutral	0,7	damaging	0,15	deleterious	3,9	23,5	0,09	0,4	neutral	0,33	disease	0,93	disease	0,77	disease	0,83	7	deleterious	0,98	neutral	0,19	deleterious	2	deleterious	0,86	low_impact	-2,51	medium_impact	0,05	high_impact	2,12	0,43	0,8	30,65	18,16	N	0,47	N	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9438	9438	G	T	MI.7125	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	232	78	G	C	Ggc/Tgc	0,36	0,98	0	probably_damaging	0,99	neutral	0,18	neutral	1,9	deleterious	-4,76	deleterious	-7,29	high_impact	3,58	neutral	0,66	damaging	0,16	deleterious	4,06	23,7	0,07	0,35	disease	0,63	disease	0,93	disease	0,73	disease	0,8	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-2,81	medium_impact	-0,18	high_impact	2,03	0,08	0,8	30,65	18,16	N	0,4	N	0,84	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9439	9439	G	C	MI.7126	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	233	78	G	A	gGc/gCc	1,98	1	0	benign	0,19	neutral	0,51	neutral	2,01	neutral	-1,88	deleterious	-4,78	medium_impact	3,23	neutral	0,74	neutral	0,34	neutral	1,41	12,82	0,29	0,45	neutral	0,18	disease	0,82	disease	0,72	disease	0,72	4	neutral	0,39	deleterious	0,66	neutral	-3	deleterious	0,47	medium_impact	-0,26	medium_impact	0,2	medium_impact	1,71	0,39	0,8	30,65	18,16	N	0,48	N	0,76	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9439	9439	G	T	MI.7127	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	233	78	G	V	gGc/gTc	1,98	1	0	probably_damaging	0,98	neutral	0,5	neutral	1,95	neutral	-2,88	deleterious	-7,32	high_impact	4,04	neutral	0,62	damaging	0,23	deleterious	3,7	23,3	0,08	0,35	neutral	0,32	disease	0,94	disease	0,74	disease	0,83	7	deleterious	0,98	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-2,51	medium_impact	0,19	high_impact	2,44	0,12	0,8	30,65	18,16	N	0,46	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9439	9439	G	A	MI.7128	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	233	78	G	D	gGc/gAc	1,98	1	0	probably_damaging	0,91	neutral	0,21	neutral	1,93	deleterious	-3,28	deleterious	-5,21	high_impact	4,38	neutral	0,67	damaging	0,2	deleterious	3,84	23,4	0,09	0,35	neutral	0,33	disease	0,93	disease	0,78	disease	0,8	6	neutral	0,94	neutral	0,15	deleterious	2	deleterious	0,74	low_impact	-1,85	medium_impact	-0,14	high_impact	2,74	0,17	0,8	30,65	18,16	P	0,57	P	0,91	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9441	9441	C	G	MI.7129	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	235	79	L	V	Ctt/Gtt	-7,28	0	0	probably_damaging	0,91	neutral	0,55	neutral	1,95	neutral	-2,03	deleterious	-2,56	medium_impact	2,6	damaging	0,55	damaging	0,01	deleterious	3,39	23	0,28	0,45	neutral	0,22	disease	0,78	disease	0,64	disease	0,68	4	neutral	0,9	neutral	0,32	deleterious	1	deleterious	0,72	low_impact	-1,85	medium_impact	0,24	medium_impact	1,15	0,34	0,8	74,71	11,52	N	0,19	N	0,81	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8863	8863	G	A	MI.713	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	337	113	V	M	Gtg/Atg	-8,43	0	0	probably_damaging	1	neutral	0,6	neutral	4,28	neutral	-1,37	deleterious	-2,57	low_impact	1,52	neutral	0,77	neutral	0,54	deleterious	3,66	23,2	0,32	0,65	disease	0,5	disease	0,52	neutral	0,39	neutral	0,39	2	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,39	medium_impact	0,21	0,81	0,9	42,04	7,9	N	0,21	N	0,96	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9441	9441	C	T	MI.7130	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	235	79	L	F	Ctt/Ttt	-7,28	0	0	probably_damaging	0,99	neutral	0,73	neutral	1,93	neutral	-2,23	deleterious	-3,5	low_impact	1,84	damaging	0,57	damaging	0,02	deleterious	3,92	23,5	0,29	0,45	neutral	0,26	disease	0,76	disease	0,64	disease	0,55	1	deleterious	0,99	neutral	0,37	neutral	-2	deleterious	0,78	low_impact	-2,81	medium_impact	0,44	medium_impact	0,47	0,51	0,8	74,71	11,52	N	0,19	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9441	9441	C	A	MI.7131	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	235	79	L	I	Ctt/Att	-7,28	0	0	probably_damaging	0,96	neutral	0,46	neutral	1,98	neutral	-1,74	neutral	-1,75	medium_impact	2,34	damaging	0,49	damaging	0,07	deleterious	4,07	23,7	0,3	0,45	neutral	0,23	disease	0,64	neutral	0,31	neutral	0,43	1	neutral	0,96	neutral	0,25	deleterious	1	deleterious	0,71	low_impact	-2,21	medium_impact	0,15	medium_impact	0,92	0,42	0,8	74,71	11,52	N	0,29	N	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9442	9442	T	A	MI.7132	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	236	79	L	H	cTt/cAt	-0,33	0	0	probably_damaging	1	neutral	0,55	neutral	1,82	deleterious	-5,1	deleterious	-6,19	medium_impact	3,11	damaging	0,58	damaging	0,02	deleterious	4,01	23,6	0,06	0,35	neutral	0,43	disease	0,86	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,83	low_impact	-3,78	medium_impact	0,24	medium_impact	1,61	0,15	0,8	74,71	11,52	N	0,22	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9442	9442	T	G	MI.7133	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	236	79	L	R	cTt/cGt	-0,33	0	0	probably_damaging	0,99	neutral	0,38	neutral	1,83	deleterious	-4,4	deleterious	-5,25	medium_impact	2,47	neutral	0,71	damaging	0,02	deleterious	4,12	23,8	0,03	0,35	neutral	0,25	disease	0,93	disease	0,75	disease	0,79	6	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,85	low_impact	-2,81	medium_impact	0,07	medium_impact	1,03	0,11	0,8	74,71	11,52	N	0,23	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9442	9442	T	C	MI.7134	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	236	79	L	P	cTt/cCt	-0,33	0	0	probably_damaging	1	neutral	0,21	neutral	1,83	deleterious	-4,25	deleterious	-6,19	medium_impact	3,17	damaging	0,56	damaging	0,02	deleterious	3,74	23,3	0,03	0,35	neutral	0,32	disease	0,87	neutral	0,42	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,84	low_impact	-3,78	medium_impact	-0,14	medium_impact	1,66	0,15	0,8	74,71	11,52	N	0,26	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9444	9444	C	G	MI.7135	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	238	80	R	G	Cga/Gga	-7,97	0	0	probably_damaging	0,97	neutral	0,34	neutral	2,15	neutral	-2,91	deleterious	-6,32	high_impact	3,54	neutral	0,63	damaging	0,01	deleterious	4,14	23,8	0,08	0,35	neutral	0,3	disease	0,81	disease	0,68	disease	0,7	4	neutral	0,97	neutral	0,19	deleterious	2	deleterious	0,76	low_impact	-2,34	medium_impact	0,03	medium_impact	1,99	0,16	0,8	73,95	11,62	N	0,26	N	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9444	9444	C	T	MI.7136	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	238	80	R	W	Cga/Tga	-7,97	0	0	probably_damaging	1	neutral	0,18	neutral	2,11	deleterious	-4,72	deleterious	-7,25	high_impact	3,81	neutral	0,67	damaging	0,02	deleterious	5,07	25,3	0,1	0,4	disease	0,67	disease	0,9	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,18	high_impact	2,23	0,61	0,8	73,95	11,62	N	0,31	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9445	9445	G	A	MI.7137	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	239	80	R	Q	cGa/cAa	2,44	0,97	0	probably_damaging	0,94	neutral	0,3	neutral	2,2	neutral	-1,87	deleterious	-3,48	medium_impact	2,65	damaging	0,59	damaging	0,03	deleterious	4,38	24,1	0,28	0,45	neutral	0,2	disease	0,79	neutral	0,46	disease	0,52	0	neutral	0,95	neutral	0,18	deleterious	1	deleterious	0,73	low_impact	-2,03	medium_impact	-0,02	medium_impact	1,19	0,77	0,85	73,95	11,62	N	0,39	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9445	9445	G	C	MI.7138	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	239	80	R	P	cGa/cCa	2,44	0,97	0	probably_damaging	0,99	neutral	0,21	neutral	2,13	deleterious	-3,54	deleterious	-6,23	high_impact	4	neutral	0,61	damaging	0,03	deleterious	4,15	23,8	0,02	0,35	neutral	0,38	disease	0,92	disease	0,68	disease	0,74	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-2,81	medium_impact	-0,14	high_impact	2,4	0,09	0,8	73,95	11,62	N	0,37	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9445	9445	G	T	MI.7139	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	239	80	R	L	cGa/cTa	2,44	0,97	0	probably_damaging	0,93	neutral	0,66	neutral	2,16	neutral	-2,52	deleterious	-6,32	medium_impact	2,73	neutral	0,63	damaging	0,02	deleterious	4,26	23,9	0,09	0,35	neutral	0,21	disease	0,91	disease	0,65	disease	0,73	5	neutral	0,92	neutral	0,37	deleterious	1	deleterious	0,78	low_impact	-1,96	medium_impact	0,36	medium_impact	1,26	0	0,8	73,95	11,62	N	0,3	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8863	8863	G	T	MI.714	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	337	113	V	L	Gtg/Ttg	-8,43	0	0	probably_damaging	0,98	neutral	0,52	neutral	4,5	neutral	0,72	neutral	-2,46	low_impact	1,42	neutral	0,75	neutral	0,58	deleterious	3,67	23,2	0,4	0,65	neutral	0,33	disease	0,7	neutral	0,41	neutral	0,42	2	neutral	0,98	neutral	0,27	neutral	-2	deleterious	0,72	low_impact	-2,36	medium_impact	0,31	medium_impact	0,12	0,75	0,9	42,04	7,9	N	0,28	N	0,7	polymorphism	0,99	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9447	9447	T	G	MI.7140	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	241	81	Y	D	Tac/Gac	-2,88	0	0	probably_damaging	1	neutral	0,2	neutral	2,5	deleterious	-3,36	deleterious	-6,33	medium_impact	2,89	neutral	0,61	neutral	0,41	deleterious	3,9	23,5	0,03	0,35	neutral	0,44	disease	0,83	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,8	low_impact	-3,78	medium_impact	-0,15	medium_impact	1,41	0,13	0,8	73,95	11,7	N	0,31	N	0,99	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9447	9447	T	A	MI.7141	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	241	81	Y	N	Tac/Aac	-2,88	0	0	probably_damaging	1	neutral	0,28	neutral	2,5	neutral	-2,52	deleterious	-5,89	medium_impact	2,75	neutral	0,63	neutral	0,42	deleterious	3,98	23,6	0,07	0,35	neutral	0,34	disease	0,76	disease	0,55	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	-0,04	medium_impact	1,28	0,11	0,8	73,95	11,7	N	0,34	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9447	9447	T	C	MI.7142	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	241	81	Y	H	Tac/Cac	-2,88	0	0	probably_damaging	0,99	neutral	0,49	neutral	2,5	neutral	-2,8	deleterious	-3,56	medium_impact	3,44	neutral	0,62	neutral	0,44	deleterious	3,51	23,1	0,14	0,4	neutral	0,4	disease	0,69	disease	0,63	disease	0,7	4	deleterious	0,99	neutral	0,25	deleterious	1	deleterious	0,78	low_impact	-2,81	medium_impact	0,18	medium_impact	1,9	0,11	0,8	73,95	11,7	N	0,33	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9448	9448	A	T	MI.7143	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	242	81	Y	F	tAc/tTc	7,53	1	0	probably_damaging	0,93	neutral	0,67	neutral	2,62	neutral	-0,02	neutral	-1,9	neutral_impact	0,7	neutral	0,65	neutral	0,76	deleterious	3,18	22,7	0,25	0,45	neutral	0,19	disease	0,57	neutral	0,39	neutral	0,45	1	neutral	0,92	neutral	0,37	neutral	-2	deleterious	0,68	low_impact	-1,96	medium_impact	0,37	medium_impact	-0,56	0,38	0,8	73,95	11,7	P	0,53	P	0,72	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9448	9448	A	C	MI.7144	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	242	81	Y	S	tAc/tCc	7,53	1	0	probably_damaging	0,99	neutral	0,39	neutral	2,55	neutral	-0,93	deleterious	-5,42	medium_impact	2,54	neutral	0,66	neutral	0,46	deleterious	3,58	23,2	0,06	0,35	neutral	0,14	disease	0,74	disease	0,61	disease	0,66	3	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,74	low_impact	-2,81	medium_impact	0,08	medium_impact	1,09	0,2	0,8	73,95	11,7	N	0,44	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9448	9448	A	G	MI.7145	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	242	81	Y	C	tAc/tGc	7,53	1	0	probably_damaging	1	neutral	0,16	neutral	2,49	neutral	-2,66	deleterious	-5,11	medium_impact	3,09	neutral	0,66	neutral	0,44	deleterious	3,37	22,9	0,05	0,35	neutral	0,4	disease	0,83	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,78	low_impact	-3,78	medium_impact	-0,22	medium_impact	1,59	0,08	0,8	73,95	11,7	N	0,48	N	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9450	9450	G	C	MI.7146	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	244	82	G	R	Ggg/Cgg	-6,81	0	0	probably_damaging	1	neutral	0,35	neutral	1,64	deleterious	-6,11	deleterious	-7,42	high_impact	4,39	neutral	0,67	damaging	0,02	deleterious	3,9	23,5	0,02	0,35	disease	0,89	disease	0,91	disease	0,83	disease	0,85	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,94	low_impact	-3,78	medium_impact	0,04	high_impact	2,75	0,61	0,8	74,33	11,59	N	0,44	N	0,99	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9450	9450	G	T	MI.7147	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	244	82	G	W	Ggg/Tgg	-6,81	0	0	probably_damaging	1	neutral	0,19	neutral	1,63	deleterious	-8,07	deleterious	-7,42	high_impact	4,2	neutral	0,64	damaging	0,02	deleterious	4,36	24,1	0,03	0,35	disease	0,97	disease	0,92	disease	0,77	disease	0,84	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,93	low_impact	-3,78	medium_impact	-0,17	high_impact	2,58	0,17	0,8	74,33	11,59	N	0,34	N	0,98	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9451	9451	G	A	MI.7148	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	245	82	G	E	gGg/gAg	6,14	1	0	probably_damaging	1	neutral	0,27	neutral	1,65	deleterious	-5,85	deleterious	-7,41	high_impact	4,75	damaging	0,57	damaging	0,01	deleterious	3,8	23,4	0,02	0,35	disease	0,86	disease	0,9	disease	0,82	disease	0,86	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,92	low_impact	-3,78	medium_impact	-0,06	high_impact	3,07	0,28	0,8	74,33	11,59	P	0,69	P	1	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9451	9451	G	C	MI.7149	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	245	82	G	A	gGg/gCg	6,14	1	0	probably_damaging	1	neutral	0,5	neutral	1,86	neutral	-2,38	deleterious	-5,56	medium_impact	3,39	damaging	0,58	damaging	0,02	deleterious	3,05	22,4	0,06	0,35	disease	0,73	disease	0,78	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,88	low_impact	-3,78	medium_impact	0,19	medium_impact	1,86	0,52	0,8	74,33	11,59	N	0,47	N	0,3	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8864	8864	T	A	MI.715	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	338	113	V	E	gTg/gAg	4,06	1	0	probably_damaging	1	deleterious	0,03	neutral	4,23	neutral	-2,83	deleterious	-5,42	medium_impact	3,25	neutral	0,77	neutral	0,44	deleterious	4,77	24,7	0,15	0,65	disease	0,75	disease	0,92	disease	0,73	disease	0,77	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,86	low_impact	-3,6	medium_impact	-0,56	medium_impact	1,69	0,57	0,9	42,04	7,9	N	0,44	N	0,98	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9451	9451	G	T	MI.7150	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	245	82	G	V	gGg/gTg	6,14	1	0	probably_damaging	1	neutral	0,5	neutral	1,66	deleterious	-5,16	deleterious	-8,34	high_impact	4,39	damaging	0,54	damaging	0,01	deleterious	3,7	23,3	0,02	0,35	disease	0,88	disease	0,93	disease	0,77	disease	0,85	7	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,93	low_impact	-3,78	medium_impact	0,19	high_impact	2,75	0,23	0,8	74,33	11,59	P	0,59	P	0,97	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9453	9453	A	G	MI.7151	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	247	83	M	V	Ata/Gta	-15,84	0	0	possibly_damaging	0,84	neutral	0,65	neutral	2,41	neutral	-2,01	deleterious	-3,67	medium_impact	2,52	damaging	0,45	damaging	0,07	deleterious	2,77	21,2	0,18	0,45	neutral	0,13	disease	0,86	disease	0,53	disease	0,5	0	neutral	0,81	neutral	0,41	NA	0	deleterious	0,66	low_impact	-1,57	medium_impact	0,35	medium_impact	1,08	0,39	0,8	74,33	11,59	N	0,26	N	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9453	9453	A	C	MI.7152	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	247	83	M	L	Ata/Cta	-15,84	0	0	possibly_damaging	0,77	neutral	0,87	neutral	2,47	neutral	-1,88	deleterious	-2,75	medium_impact	2,8	damaging	0,57	damaging	0,04	deleterious	3,29	22,8	0,18	0,45	neutral	0,13	disease	0,88	disease	0,65	disease	0,72	4	neutral	0,73	deleterious	0,55	NA	0	deleterious	0,57	low_impact	-1,38	medium_impact	0,66	medium_impact	1,33	0,38	0,8	74,33	11,59	N	0,22	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9453	9453	A	T	MI.7153	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	247	83	M	L	Ata/Tta	-15,84	0	0	possibly_damaging	0,77	neutral	0,87	neutral	2,47	neutral	-1,88	deleterious	-2,75	medium_impact	2,8	damaging	0,57	damaging	0,04	deleterious	3,4	23	0,18	0,45	neutral	0,13	disease	0,88	disease	0,65	disease	0,72	4	neutral	0,73	deleterious	0,55	NA	0	deleterious	0,57	low_impact	-1,38	medium_impact	0,66	medium_impact	1,33	0,38	0,8	74,33	11,59	N	0,22	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9454	9454	T	A	MI.7154	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	248	83	M	K	aTa/aAa	6,84	1	0	probably_damaging	0,93	neutral	0,3	neutral	2,32	deleterious	-4,65	deleterious	-5,51	high_impact	3,97	neutral	0,65	damaging	0,03	deleterious	3,92	23,5	0,02	0,35	neutral	0,36	disease	0,95	disease	0,76	disease	0,87	7	neutral	0,94	neutral	0,19	deleterious	2	deleterious	0,83	low_impact	-1,96	medium_impact	-0,02	high_impact	2,38	0,21	0,8	74,33	11,59	P	0,53	P	0,99	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9454	9454	T	C	MI.7155	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	248	83	M	T	aTa/aCa	6,84	1	0	probably_damaging	0,96	neutral	0,31	neutral	2,36	neutral	-2,1	deleterious	-5,51	medium_impact	2,6	damaging	0,6	damaging	0,06	deleterious	2,93	22	0,05	0,35	neutral	0,16	disease	0,91	disease	0,69	disease	0,74	5	neutral	0,97	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-2,21	medium_impact	-0,01	medium_impact	1,15	0,15	0,8	74,33	11,59	N	0,36	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9455	9455	A	C	MI.7156	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	249	83	M	I	atA/atC	5,91	1	0	possibly_damaging	0,88	neutral	0,96	neutral	2,4	neutral	-2,15	deleterious	-3,67	medium_impact	3,1	damaging	0,51	damaging	0,05	deleterious	3,39	23	0,12	0,4	neutral	0,11	disease	0,89	disease	0,63	disease	0,66	3	neutral	0,88	deleterious	0,54	NA	0	deleterious	0,7	low_impact	-1,71	medium_impact	0,98	medium_impact	1,6	0,45	0,8	74,33	11,59	N	0,45	N	0,95	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9455	9455	A	T	MI.7157	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	249	83	M	I	atA/atT	5,91	1	0	possibly_damaging	0,88	neutral	0,96	neutral	2,4	neutral	-2,15	deleterious	-3,67	medium_impact	3,1	damaging	0,51	damaging	0,05	deleterious	3,46	23	0,12	0,4	neutral	0,11	disease	0,89	disease	0,63	disease	0,66	3	neutral	0,88	deleterious	0,54	NA	0	deleterious	0,7	low_impact	-1,71	medium_impact	0,98	medium_impact	1,6	0,45	0,8	74,33	11,59	N	0,46	N	0,95	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9456	9456	A	C	MI.7158	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	250	84	I	L	Atc/Ctc	1,52	0,97	0	benign	0,01	neutral	0,64	neutral	2,55	neutral	-0,53	neutral	-1,4	medium_impact	1,97	damaging	0,59	neutral	0,71	deleterious	1,8	15	0,23	0,45	neutral	0,13	disease	0,65	neutral	0,36	neutral	0,45	1	neutral	0,35	deleterious	0,82	neutral	-3	neutral	0,16	medium_impact	1,07	medium_impact	0,33	medium_impact	0,58	0,64	0,8	18,39	29,81	N	0,42	N	0,53	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9456	9456	A	G	MI.7159	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	250	84	I	V	Atc/Gtc	1,52	0,97	0	benign	0	neutral	0,3	neutral	2,49	neutral	-0,61	neutral	-0,48	low_impact	1,21	neutral	0,71	neutral	0,93	neutral	-0,11	1,64	0,36	0,5	neutral	0,19	disease	0,52	neutral	0,36	neutral	0,43	1	neutral	0,7	deleterious	0,65	neutral	-6	neutral	0,14	high_impact	2,05	medium_impact	-0,02	medium_impact	-0,1	0,48	0,8	18,39	29,81	N	0,53	P	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8864	8864	T	G	MI.716	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	338	113	V	G	gTg/gGg	4,06	1	0	probably_damaging	1	neutral	0,17	neutral	4,23	neutral	-2,94	deleterious	-6,29	high_impact	3,81	neutral	0,73	neutral	0,58	deleterious	3,75	23,3	0,14	0,65	disease	0,77	disease	0,86	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,6	medium_impact	-0,1	high_impact	2,17	0,54	0,9	42,04	7,9	N	0,48	N	0,93	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9456	9456	A	T	MI.7160	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	250	84	I	F	Atc/Ttc	1,52	0,97	0	benign	0,1	neutral	1	neutral	2,42	neutral	-2,1	deleterious	-3,1	medium_impact	2,66	neutral	0,63	neutral	0,47	deleterious	1,9	15,61	0,13	0,4	neutral	0,33	disease	0,87	disease	0,54	disease	0,65	3	neutral	0,1	deleterious	0,95	neutral	-3	neutral	0,3	medium_impact	0,06	high_impact	1,9	medium_impact	1,2	0,61	0,8	18,39	29,81	N	0,38	N	0,81	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9457	9457	T	C	MI.7161	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	251	84	I	T	aTc/aCc	0,13	0,91	0	benign	0	neutral	0,13	neutral	2,43	neutral	-1,8	deleterious	-3,13	medium_impact	2,8	neutral	0,62	neutral	0,56	neutral	1,44	12,98	0,07	0,35	neutral	0,25	disease	0,81	disease	0,58	disease	0,63	3	neutral	0,87	deleterious	0,57	neutral	-3	neutral	0,23	high_impact	2,05	medium_impact	-0,28	medium_impact	1,33	0,28	0,8	18,39	29,81	N	0,41	N	0,28	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9457	9457	T	G	MI.7162	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	251	84	I	S	aTc/aGc	0,13	0,91	0	benign	0,06	neutral	0,13	neutral	2,44	neutral	-1,02	deleterious	-4,05	medium_impact	2,48	neutral	0,67	neutral	0,4	deleterious	2,43	19,04	0,03	0,35	neutral	0,34	disease	0,9	disease	0,61	disease	0,68	4	neutral	0,86	deleterious	0,54	neutral	-3	neutral	0,3	medium_impact	0,29	medium_impact	-0,28	medium_impact	1,04	0,27	0,8	18,39	29,81	N	0,35	N	0,74	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9457	9457	T	A	MI.7163	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	251	84	I	N	aTc/aAc	0,13	0,91	0	benign	0,15	neutral	0,1	neutral	2,4	deleterious	-3,49	deleterious	-5,19	high_impact	3,87	neutral	0,61	neutral	0,34	deleterious	2,88	21,8	0,07	0,35	disease	0,51	disease	0,91	disease	0,54	disease	0,71	4	neutral	0,89	deleterious	0,48	neutral	-2	deleterious	0,48	medium_impact	-0,14	medium_impact	-0,35	high_impact	2,29	0,28	0,8	18,39	29,81	N	0,39	N	0,83	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9458	9458	C	A	MI.7164	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	252	84	I	M	atC/atA	4,76	0,97	0	benign	0,25	neutral	0,61	neutral	2,41	neutral	-1,95	neutral	-2,09	medium_impact	2,58	neutral	0,7	neutral	0,58	deleterious	1,89	15,52	0,17	0,45	neutral	0,28	disease	0,7	neutral	0,5	disease	0,51	0	neutral	0,28	deleterious	0,68	neutral	-3	neutral	0,25	medium_impact	-0,41	medium_impact	0,3	medium_impact	1,13	0,5	0,8	18,39	29,81	N	0,47	N	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9458	9458	C	G	MI.7165	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	252	84	I	M	atC/atG	4,76	0,97	0	benign	0,25	neutral	0,61	neutral	2,41	neutral	-1,95	neutral	-2,09	medium_impact	2,58	neutral	0,7	neutral	0,58	neutral	1,42	12,9	0,17	0,45	neutral	0,28	disease	0,7	neutral	0,5	disease	0,51	0	neutral	0,28	deleterious	0,68	neutral	-3	neutral	0,25	medium_impact	-0,41	medium_impact	0,3	medium_impact	1,13	0,5	0,8	18,39	29,81	N	0,48	N	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9459	9459	C	G	MI.7166	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	253	85	L	V	Cta/Gta	-5,66	0	0	probably_damaging	0,96	neutral	0,14	neutral	1,65	neutral	-2,62	deleterious	-2,75	medium_impact	2,29	damaging	0,51	damaging	0,01	deleterious	3,32	22,9	0,22	0,45	neutral	0,25	disease	0,82	disease	0,63	disease	0,68	4	neutral	0,98	neutral	0,09	deleterious	1	deleterious	0,76	low_impact	-2,21	medium_impact	-0,26	medium_impact	0,87	0,62	0,8	73,18	11,63	N	0,25	N	0,81	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9459	9459	C	A	MI.7167	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	253	85	L	M	Cta/Ata	-5,66	0	0	probably_damaging	1	neutral	0,21	neutral	1,57	deleterious	-3,51	neutral	-1,82	medium_impact	2,54	damaging	0,56	damaging	0,05	deleterious	3,63	23,2	0,23	0,45	neutral	0,35	disease	0,64	disease	0,55	neutral	0,45	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,74	low_impact	-3,78	medium_impact	-0,14	medium_impact	1,09	0,41	0,8	73,18	11,63	N	0,27	N	0,85	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9460	9460	T	A	MI.7168	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	254	85	L	Q	cTa/cAa	-0,33	0	0	probably_damaging	1	deleterious	0,02	neutral	1,5	deleterious	-5,79	deleterious	-5,5	high_impact	4,49	damaging	0,59	damaging	0,03	deleterious	4	23,6	0,02	0,35	disease	0,58	disease	0,88	disease	0,61	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,78	medium_impact	-0,77	high_impact	2,84	0,42	0,8	73,18	11,63	N	0,36	N	0,97	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9460	9460	T	G	MI.7169	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	254	85	L	R	cTa/cGa	-0,33	0	0	probably_damaging	1	neutral	0,09	neutral	1,5	deleterious	-5,74	deleterious	-5,5	high_impact	4,49	neutral	0,66	damaging	0,02	deleterious	4,11	23,7	0,02	0,35	disease	0,56	disease	0,95	disease	0,75	disease	0,88	8	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,9	low_impact	-3,78	medium_impact	-0,38	high_impact	2,84	0,27	0,8	73,18	11,63	N	0,44	N	0,99	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8864	8864	T	C	MI.717	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	338	113	V	A	gTg/gCg	4,06	1	0	probably_damaging	0,99	neutral	0,09	neutral	4,28	neutral	-1,25	deleterious	-3,43	medium_impact	3,46	neutral	0,81	neutral	0,62	deleterious	3,52	23,1	0,35	0,65	neutral	0,41	disease	0,72	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,74	low_impact	-2,65	medium_impact	-0,28	medium_impact	1,87	0,51	0,9	42,04	7,9	N	0,48	N	0,6	disease_causing	0,98	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9460	9460	T	C	MI.7170	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	254	85	L	P	cTa/cCa	-0,33	0	0	probably_damaging	1	deleterious	0,01	neutral	1,49	deleterious	-6,52	deleterious	-6,42	high_impact	3,8	damaging	0,48	damaging	0,03	deleterious	3,84	23,4	0,02	0,35	disease	0,6	disease	0,89	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-3,78	medium_impact	-0,95	high_impact	2,22	0,45	0,8	73,18	11,63	N	0,28	N	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9462	9462	T	C	MI.7171	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	256	86	F	L	Ttt/Ctt	-7,51	0	0	probably_damaging	0,95	neutral	1	neutral	1,48	deleterious	-4,47	deleterious	-5,45	high_impact	3,64	neutral	0,65	damaging	0,03	deleterious	3,88	23,5	0,05	0,35	neutral	0,32	disease	0,88	disease	0,73	disease	0,73	5	neutral	0,95	deleterious	0,53	deleterious	2	deleterious	0,78	low_impact	-2,11	high_impact	1,9	high_impact	2,08	0,64	0,8	73,56	11,56	N	0,22	N	0,92	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9462	9462	T	A	MI.7172	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	256	86	F	I	Ttt/Att	-7,51	0	0	probably_damaging	0,97	neutral	0,86	neutral	1,41	deleterious	-5,06	deleterious	-5,45	high_impact	4,39	neutral	0,69	damaging	0,02	deleterious	4,28	24	0,07	0,35	neutral	0,35	disease	0,92	disease	0,73	disease	0,76	5	neutral	0,96	neutral	0,45	deleterious	2	deleterious	0,81	low_impact	-2,34	medium_impact	0,64	high_impact	2,75	0,51	0,8	73,56	11,56	N	0,32	N	0,96	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9462	9462	T	G	MI.7173	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	256	86	F	V	Ttt/Gtt	-7,51	0	0	probably_damaging	0,98	neutral	0,31	neutral	1,41	deleterious	-5,36	deleterious	-6,35	high_impact	4,19	neutral	0,66	damaging	0,02	deleterious	3,86	23,5	0,05	0,35	neutral	0,41	disease	0,94	disease	0,77	disease	0,84	7	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-2,51	medium_impact	-0,01	high_impact	2,57	0,43	0,8	73,56	11,56	N	0,38	N	0,97	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9463	9463	T	A	MI.7174	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	257	86	F	Y	tTt/tAt	5,91	1	0	probably_damaging	0,95	neutral	0,16	neutral	1,46	deleterious	-3,57	deleterious	-2,72	high_impact	4,04	neutral	0,71	damaging	0,03	deleterious	4,25	23,9	0,09	0,35	neutral	0,4	disease	0,89	disease	0,73	disease	0,76	5	neutral	0,97	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-2,11	medium_impact	-0,22	high_impact	2,44	0,62	0,8	73,56	11,56	P	0,59	P	0,8	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9463	9463	T	G	MI.7175	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	257	86	F	C	tTt/tGt	5,91	1	0	probably_damaging	1	deleterious	0,03	neutral	1,35	deleterious	-7,81	deleterious	-7,27	high_impact	4,74	neutral	0,72	damaging	0,02	deleterious	4,01	23,6	0,02	0,35	disease	0,78	disease	0,92	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,86	low_impact	-3,78	medium_impact	-0,67	high_impact	3,07	0,29	0,8	73,56	11,56	P	0,59	P	0,98	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9463	9463	T	C	MI.7176	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	257	86	F	S	tTt/tCt	5,91	1	0	probably_damaging	0,99	neutral	0,25	neutral	1,38	deleterious	-6,41	deleterious	-7,25	high_impact	4,04	neutral	0,72	damaging	0,02	deleterious	4,22	23,9	0,02	0,35	disease	0,59	disease	0,92	disease	0,75	disease	0,8	6	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,85	low_impact	-2,81	medium_impact	-0,08	high_impact	2,44	0,37	0,8	73,56	11,56	N	0,53	P	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9464	9464	T	A	MI.7177	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	258	86	F	L	ttT/ttA	7,53	1	0	probably_damaging	0,95	neutral	1	neutral	1,48	deleterious	-4,47	deleterious	-5,45	high_impact	3,64	neutral	0,65	damaging	0,03	deleterious	4,39	24,1	0,05	0,35	neutral	0,32	disease	0,88	disease	0,73	disease	0,73	5	neutral	0,95	deleterious	0,53	deleterious	2	deleterious	0,78	low_impact	-2,11	high_impact	1,9	high_impact	2,08	0,64	0,8	73,56	11,56	N	0,47	N	0,92	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9464	9464	T	G	MI.7178	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	258	86	F	L	ttT/ttG	7,53	1	0	probably_damaging	0,95	neutral	1	neutral	1,48	deleterious	-4,47	deleterious	-5,45	high_impact	3,64	neutral	0,65	damaging	0,03	deleterious	4,28	24	0,05	0,35	neutral	0,32	disease	0,88	disease	0,73	disease	0,73	5	neutral	0,95	deleterious	0,53	deleterious	2	deleterious	0,78	low_impact	-2,11	high_impact	1,9	high_impact	2,08	0,64	0,8	73,56	11,56	N	0,46	N	0,92	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9465	9465	A	G	MI.7179	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	259	87	I	V	Att/Gtt	-3,11	0	0	possibly_damaging	0,79	neutral	0,31	neutral	2,06	neutral	-2,3	neutral	-0,91	medium_impact	3,07	damaging	0,53	damaging	0,08	deleterious	3	22,2	0,31	0,45	neutral	0,18	disease	0,61	disease	0,67	neutral	0,44	1	neutral	0,82	neutral	0,26	NA	0	deleterious	0,51	low_impact	-1,43	medium_impact	-0,01	medium_impact	1,57	0,64	0,8	74,33	11,54	N	0,31	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8866	8866	A	G	MI.718	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	340	114	I	V	Att/Gtt	-3,8	0	0	benign	0	neutral	0,11	neutral	4,22	neutral	-1,27	neutral	-0,39	low_impact	1,47	neutral	0,93	neutral	0,98	neutral	-0,14	1,44	0,52	0,65	disease	0,61	neutral	0,44	neutral	0,39	disease	0,6	2	neutral	0,89	deleterious	0,56	neutral	-6	neutral	0,16	high_impact	2,09	medium_impact	-0,22	medium_impact	0,16	0,5	0,9	18,14	12,08	N	0,39	N	0	polymorphism	1	0,01	.	.	.	.	.	.	COSM1331624	.	.	.	.	.	.	.	.
chrM	9465	9465	A	C	MI.7180	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	259	87	I	L	Att/Ctt	-3,11	0	0	probably_damaging	0,91	neutral	0,59	neutral	2,52	neutral	-0,16	neutral	-1,82	low_impact	1,7	damaging	0,59	damaging	0,04	deleterious	3,73	23,3	0,17	0,45	neutral	0,11	disease	0,78	disease	0,67	disease	0,63	3	neutral	0,9	neutral	0,34	neutral	-2	deleterious	0,54	low_impact	-1,85	medium_impact	0,28	medium_impact	0,34	0,55	0,8	74,33	11,54	N	0,22	N	0,83	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9465	9465	A	T	MI.7181	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	259	87	I	F	Att/Ttt	-3,11	0	0	probably_damaging	0,98	neutral	1	neutral	1,93	deleterious	-4,5	deleterious	-3,63	high_impact	4,04	damaging	0,57	damaging	0,02	deleterious	3,65	23,2	0,03	0,35	disease	0,54	disease	0,89	disease	0,77	disease	0,79	6	deleterious	0,98	deleterious	0,51	deleterious	2	deleterious	0,83	low_impact	-2,51	high_impact	1,9	high_impact	2,44	0,63	0,8	74,33	11,54	N	0,3	N	0,94	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9466	9466	T	C	MI.7182	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	260	87	I	T	aTt/aCt	8,69	1	0	probably_damaging	0,99	neutral	0,33	neutral	1,91	deleterious	-5,89	deleterious	-4,53	high_impact	4,04	damaging	0,57	damaging	0,02	deleterious	3,24	22,8	0,02	0,35	disease	0,6	disease	0,82	disease	0,74	disease	0,76	5	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-2,81	medium_impact	0,02	high_impact	2,44	0,26	0,8	74,33	11,54	N	0,51	P	0,91	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9466	9466	T	G	MI.7183	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	260	87	I	S	aTt/aGt	8,69	1	0	probably_damaging	0,99	neutral	0,64	neutral	1,9	deleterious	-7,38	deleterious	-5,43	high_impact	4,59	neutral	0,61	damaging	0,06	deleterious	4,15	23,8	0,01	0,35	disease	0,73	disease	0,9	disease	0,73	disease	0,78	6	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,85	low_impact	-2,81	medium_impact	0,33	high_impact	2,93	0,29	0,8	74,33	11,54	P	0,55	P	0,93	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9466	9466	T	A	MI.7184	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	260	87	I	N	aTt/aAt	8,69	1	0	probably_damaging	1	neutral	0,24	neutral	1,9	deleterious	-8,23	deleterious	-6,35	high_impact	4,59	damaging	0,58	damaging	0,02	deleterious	4,22	23,9	0,02	0,35	disease	0,84	disease	0,91	disease	0,77	disease	0,81	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	-0,09	high_impact	2,93	0,33	0,8	74,33	11,54	P	0,58	P	0,97	polymorphism	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9467	9467	T	A	MI.7185	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	261	87	I	M	atT/atA	5,91	1	0	probably_damaging	0,99	neutral	0,1	neutral	1,98	deleterious	-3,39	deleterious	-2,72	high_impact	4,25	neutral	0,61	damaging	0,02	deleterious	3,6	23,2	0,07	0,35	neutral	0,49	disease	0,77	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,75	low_impact	-2,81	medium_impact	-0,35	high_impact	2,63	0,64	0,8	74,33	11,54	P	0,58	P	0,66	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9467	9467	T	G	MI.7186	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	261	87	I	M	atT/atG	5,91	1	0	probably_damaging	0,99	neutral	0,1	neutral	1,98	deleterious	-3,39	deleterious	-2,72	high_impact	4,25	neutral	0,61	damaging	0,02	deleterious	3,31	22,9	0,07	0,35	neutral	0,49	disease	0,77	disease	0,74	disease	0,74	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,75	low_impact	-2,81	medium_impact	-0,35	high_impact	2,63	0,64	0,8	74,33	11,54	P	0,57	P	0,66	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9468	9468	A	G	MI.7187	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	262	88	T	A	Acc/Gcc	-2,19	0	0,01	benign	0,03	neutral	0,48	neutral	2,33	neutral	0,14	neutral	-1,35	neutral_impact	0,37	neutral	0,75	neutral	0,72	deleterious	0,33	5,99	0,28	0,45	neutral	0,14	neutral	0,48	neutral	0,41	neutral	0,44	1	neutral	0,49	deleterious	0,73	neutral	-6	neutral	0,1	medium_impact	0,6	medium_impact	0,17	medium_impact	-0,85	0,39	0,8	16,09	18,26	N	0,33	N	0,16	polymorphism	1	0,03	rs879015841	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9468	9468	A	T	MI.7188	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	262	88	T	S	Acc/Tcc	-2,19	0	0,01	benign	0,09	neutral	0,26	neutral	2,28	neutral	-0,81	neutral	-1,89	neutral_impact	0,62	neutral	0,69	neutral	0,69	neutral	1,37	12,66	0,33	0,5	neutral	0,13	disease	0,61	disease	0,55	disease	0,62	2	neutral	0,71	deleterious	0,59	neutral	-6	neutral	0,14	medium_impact	0,11	medium_impact	-0,07	medium_impact	-0,63	0,73	0,85	16,09	18,26	N	0,37	N	0,34	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9468	9468	A	C	MI.7189	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	262	88	T	P	Acc/Ccc	-2,19	0	0,01	benign	0,37	neutral	0,1	neutral	2,25	neutral	-2,31	deleterious	-3,07	medium_impact	2,92	damaging	0,59	neutral	0,34	neutral	1,76	14,77	0,05	0,35	neutral	0,39	disease	0,9	disease	0,71	disease	0,8	6	neutral	0,88	neutral	0,37	neutral	-3	neutral	0,43	medium_impact	-0,64	medium_impact	-0,35	medium_impact	1,43	0,47	0,8	16,09	18,26	N	0,33	N	0,74	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8866	8866	A	C	MI.719	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	340	114	I	L	Att/Ctt	-3,8	0	0	benign	0	neutral	1	neutral	4,44	neutral	0,26	neutral	-0,57	neutral_impact	-0,05	neutral	0,89	neutral	0,94	neutral	-0,36	0,47	0,29	0,65	disease	0,51	neutral	0,2	neutral	0,27	neutral	0,29	4	neutral	0	deleterious	1	neutral	-6	neutral	0,14	high_impact	2,09	high_impact	1,98	low_impact	-1,14	0,65	0,9	18,14	12,08	N	0,33	N	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9469	9469	C	A	MI.7190	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	263	88	T	N	aCc/aAc	0,59	0	0	benign	0,37	neutral	0,06	neutral	2,26	neutral	-1,87	deleterious	-2,98	medium_impact	2,92	neutral	0,66	neutral	0,51	deleterious	1,92	15,69	0,26	0,45	neutral	0,31	disease	0,81	disease	0,6	disease	0,76	5	neutral	0,93	neutral	0,35	neutral	-3	neutral	0,34	medium_impact	-0,64	medium_impact	-0,49	medium_impact	1,43	0,56	0,8	16,09	18,26	N	0,39	N	0,53	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9469	9469	C	T	MI.7191	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	263	88	T	I	aCc/aTc	0,59	0	0	benign	0	neutral	0,72	neutral	2,49	neutral	1,59	neutral	-0,16	neutral_impact	-0,33	neutral	0,74	neutral	0,93	deleterious	0,29	5,63	0,13	0,4	neutral	0,12	disease	0,58	neutral	0,37	neutral	0,43	1	neutral	0,28	deleterious	0,86	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	0,43	low_impact	-1,48	0,72	0,85	16,09	18,26	N	0,36	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9469	9469	C	G	MI.7192	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	263	88	T	S	aCc/aGc	0,59	0	0	benign	0,09	neutral	0,26	neutral	2,28	neutral	-0,81	neutral	-1,89	neutral_impact	0,62	neutral	0,69	neutral	0,69	neutral	1,58	13,76	0,33	0,5	neutral	0,13	disease	0,61	disease	0,55	disease	0,62	2	neutral	0,71	deleterious	0,59	neutral	-6	neutral	0,14	medium_impact	0,11	medium_impact	-0,07	medium_impact	-0,63	0,73	0,85	16,09	18,26	N	0,39	N	0,34	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9471	9471	T	C	MI.7193	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	265	89	S	P	Tca/Cca	-5,19	0	0	probably_damaging	1	neutral	0,06	neutral	1,49	deleterious	-5,22	deleterious	-4,56	high_impact	4,18	damaging	0,52	damaging	0,05	deleterious	3,91	23,5	0,03	0,35	disease	0,65	disease	0,87	disease	0,82	disease	0,82	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,49	high_impact	2,56	0,33	0,8	74,71	11,51	N	0,43	N	0,98	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9471	9471	T	A	MI.7194	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	265	89	S	T	Tca/Aca	-5,19	0	0	probably_damaging	0,96	neutral	0,15	neutral	1,54	deleterious	-3,87	deleterious	-2,72	medium_impact	3,23	damaging	0,53	damaging	0,03	deleterious	3,73	23,3	0,18	0,45	neutral	0,21	disease	0,73	disease	0,74	disease	0,69	4	neutral	0,98	neutral	0,1	deleterious	1	deleterious	0,72	low_impact	-2,21	medium_impact	-0,24	medium_impact	1,71	0,71	0,85	74,71	11,51	N	0,31	N	0,63	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9471	9471	T	G	MI.7195	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	265	89	S	A	Tca/Gca	-5,19	0	0	probably_damaging	0,98	neutral	0,16	neutral	1,59	deleterious	-3,09	deleterious	-2,72	medium_impact	3,01	damaging	0,57	damaging	0,09	deleterious	3,65	23,2	0,14	0,4	neutral	0,22	disease	0,72	disease	0,71	disease	0,71	4	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,67	low_impact	-2,51	medium_impact	-0,22	medium_impact	1,52	0,5	0,8	74,71	11,51	N	0,26	N	0,4	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9472	9472	C	G	MI.7196	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	266	89	S	W	tCa/tGa	7,53	1	0	probably_damaging	1	neutral	0,05	neutral	1,47	deleterious	-7,87	deleterious	-6,37	high_impact	4,38	neutral	0,62	damaging	0,02	deleterious	4,27	24	0,04	0,35	disease	0,92	disease	0,93	disease	0,77	disease	0,86	7	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	-0,54	high_impact	2,74	0,15	0,8	74,71	11,51	P	0,52	P	1	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9472	9472	C	T	MI.7197	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	266	89	S	L	tCa/tTa	7,53	1	0	probably_damaging	1	neutral	0,54	neutral	1,5	deleterious	-4,81	deleterious	-5,45	high_impact	4,38	damaging	0,57	damaging	0,03	deleterious	4,58	24,4	0,02	0,35	disease	0,63	disease	0,91	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	0,23	high_impact	2,74	0,46	0,8	74,71	11,51	P	0,53	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9474	9474	G	A	MI.7198	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	268	90	E	K	Gaa/Aaa	-4,04	0	0	probably_damaging	0,99	neutral	0,35	neutral	1,56	deleterious	-4,69	deleterious	-3,63	high_impact	4,21	damaging	0,52	damaging	0,04	deleterious	4,39	24,1	0,05	0,35	disease	0,55	disease	0,92	disease	0,83	disease	0,83	7	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,86	low_impact	-2,81	medium_impact	0,04	high_impact	2,59	0,76	0,85	73,95	11,74	N	0,45	N	0,97	polymorphism	1	0,5	.	.	.	.	.	.	COSM1138432	.	.	.	.	.	.	.	.
chrM	9474	9474	G	C	MI.7199	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	268	90	E	Q	Gaa/Caa	-4,04	0	0	probably_damaging	0,99	neutral	0,33	neutral	1,55	deleterious	-5,03	deleterious	-2,72	high_impact	4,76	damaging	0,56	damaging	0,05	deleterious	3,3	22,9	0,1	0,4	disease	0,59	disease	0,79	disease	0,78	disease	0,76	5	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-2,81	medium_impact	0,02	high_impact	3,08	0,62	0,8	73,95	11,74	P	0,68	P	0,87	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8557	8557	G	A	MI.72	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	31	11	A	T	Gcc/Acc	-0,8	0	0,02	benign	0,01	neutral	0,33	neutral	4,68	neutral	-0,25	neutral	1,16	neutral_impact	0	neutral	0,99	neutral	0,95	deleterious	0,67	8,62	0,49	0,65	neutral	0,32	neutral	0,32	neutral	0,19	neutral	0,46	1	neutral	0,67	deleterious	0,66	neutral	-6	neutral	0,11	medium_impact	1,14	medium_impact	0,12	low_impact	-1,1	0,63	0,9	23,45	19,76	N	0,54	P	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8866	8866	A	T	MI.720	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	340	114	I	F	Att/Ttt	-3,8	0	0	benign	0,03	neutral	0,29	neutral	4,24	neutral	-1,12	neutral	-2,4	low_impact	1,8	neutral	0,91	neutral	0,9	neutral	1,73	14,58	0,37	0,65	disease	0,58	disease	0,79	disease	0,54	disease	0,55	1	neutral	0,69	deleterious	0,63	neutral	-6	neutral	0,28	medium_impact	0,68	medium_impact	0,07	medium_impact	0,45	0,77	0,9	18,14	12,08	N	0,3	N	0,62	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9475	9475	A	T	MI.7200	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	269	90	E	V	gAa/gTa	7,53	1	0	probably_damaging	1	neutral	0,53	neutral	1,53	deleterious	-5,55	deleterious	-6,35	high_impact	4,76	damaging	0,47	damaging	0,05	deleterious	3,98	23,6	0,03	0,35	disease	0,76	disease	0,93	disease	0,78	disease	0,82	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	0,22	high_impact	3,08	0,23	0,8	73,95	11,74	P	0,69	P	0,83	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9475	9475	A	G	MI.7201	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	269	90	E	G	gAa/gGa	7,53	1	0	probably_damaging	1	neutral	0,35	neutral	1,52	deleterious	-6,54	deleterious	-6,35	high_impact	4,76	damaging	0,52	damaging	0,06	deleterious	4,11	23,7	0,04	0,35	neutral	0,48	disease	0,86	disease	0,77	disease	0,76	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	0,04	high_impact	3,08	0,15	0,8	73,95	11,74	P	0,68	P	0,62	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9475	9475	A	C	MI.7202	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	269	90	E	A	gAa/gCa	7,53	1	0	probably_damaging	1	neutral	0,55	neutral	1,56	deleterious	-4,69	deleterious	-5,43	high_impact	4,76	damaging	0,53	damaging	0,08	deleterious	3,5	23,1	0,04	0,35	disease	0,55	disease	0,82	disease	0,76	disease	0,76	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	0,24	high_impact	3,08	0,31	0,8	73,95	11,74	P	0,72	P	0,66	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9476	9476	A	T	MI.7203	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	270	90	E	D	gaA/gaT	8,69	1	0	probably_damaging	0,98	neutral	0,25	neutral	1,76	neutral	-2,47	deleterious	-2,72	medium_impact	3,13	damaging	0,53	damaging	0,04	deleterious	3,77	23,4	0,14	0,4	neutral	0,41	disease	0,8	disease	0,77	disease	0,74	5	deleterious	0,98	neutral	0,14	deleterious	1	deleterious	0,76	low_impact	-2,51	medium_impact	-0,08	medium_impact	1,62	0,56	0,8	73,95	11,74	P	0,61	P	0,93	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9476	9476	A	C	MI.7204	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	270	90	E	D	gaA/gaC	8,69	1	0	probably_damaging	0,98	neutral	0,25	neutral	1,76	neutral	-2,47	deleterious	-2,72	medium_impact	3,13	damaging	0,53	damaging	0,04	deleterious	3,62	23,2	0,14	0,4	neutral	0,41	disease	0,8	disease	0,77	disease	0,74	5	deleterious	0,98	neutral	0,14	deleterious	1	deleterious	0,76	low_impact	-2,51	medium_impact	-0,08	medium_impact	1,62	0,56	0,8	73,95	11,74	P	0,61	P	0,93	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9477	9477	G	T	MI.7205	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	271	91	V	F	Gtt/Ttt	0,36	0,93	0,13	benign	0,2	neutral	0,49	neutral	1,98	deleterious	-3,38	deleterious	-4,07	medium_impact	3,32	neutral	0,62	neutral	0,49	deleterious	2,18	17,35	0,05	0,35	neutral	0,31	disease	0,93	disease	0,61	disease	0,69	4	neutral	0,41	deleterious	0,65	neutral	-3	deleterious	0,46	medium_impact	-0,28	medium_impact	0,18	medium_impact	1,79	0,28	0,8	26,05	16,97	N	0,4	N	0,98	polymorphism	1	0,13	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	9477	9477	G	C	MI.7206	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	271	91	V	L	Gtt/Ctt	0,36	0,93	0,13	benign	0	neutral	0,41	neutral	2,09	neutral	-1,09	neutral	-2,25	medium_impact	2,22	neutral	0,66	neutral	0,47	neutral	1,5	13,32	0,25	0,45	neutral	0,18	disease	0,79	neutral	0,47	disease	0,52	0	neutral	0,59	deleterious	0,71	neutral	-3	neutral	0,16	high_impact	2,05	medium_impact	0,1	medium_impact	0,81	0,61	0,8	26,05	16,97	N	0,41	N	0,72	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9477	9477	G	A	MI.7207	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	271	91	V	I	Gtt/Att	0,36	0,93	0,13	benign	0	neutral	0,47	neutral	2,14	neutral	-1,43	neutral	-0,54	low_impact	1,45	neutral	0,93	neutral	0,88	deleterious	0,45	7,07	0,37	0,5	neutral	0,13	neutral	0,42	neutral	0,34	neutral	0,38	2	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,09	high_impact	2,05	medium_impact	0,16	medium_impact	0,12	0,78	0,85	26,05	16,97	N	0,34	N	0,32	polymorphism	1	0,02	rs2853825	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	9478	9478	T	A	MI.7208	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	272	91	V	D	gTt/gAt	3,6	1	0	benign	0,25	deleterious	0,02	neutral	1,91	deleterious	-5,56	deleterious	-6,04	high_impact	4,36	damaging	0,57	neutral	0,42	deleterious	4,27	24	0,03	0,35	disease	0,62	disease	0,9	disease	0,71	disease	0,78	6	neutral	0,98	neutral	0,39	deleterious	2	deleterious	0,57	medium_impact	-0,41	medium_impact	-0,77	high_impact	2,73	0,14	0,8	26,05	16,97	N	0,43	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9478	9478	T	G	MI.7209	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	272	91	V	G	gTt/gGt	3,6	1	0	benign	0,12	deleterious	0,01	neutral	1,92	deleterious	-4,03	deleterious	-6,17	medium_impact	2,57	damaging	0,58	neutral	0,62	deleterious	2,1	16,84	0,05	0,35	neutral	0,39	disease	0,85	disease	0,62	disease	0,71	4	deleterious	0,99	neutral	0,45	deleterious	1	neutral	0,33	medium_impact	-0,03	medium_impact	-0,95	medium_impact	1,12	0,23	0,8	26,05	16,97	N	0,41	N	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8867	8867	T	C	MI.721	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	341	114	I	T	aTt/aCt	-1,03	0	0	benign	0	neutral	0,07	neutral	4,14	neutral	-2,63	deleterious	-2,82	medium_impact	2,1	neutral	0,91	neutral	0,63	neutral	1,42	12,89	0,38	0,65	disease	0,55	disease	0,71	disease	0,56	disease	0,62	2	neutral	0,93	deleterious	0,54	neutral	-3	neutral	0,21	high_impact	2,09	medium_impact	-0,34	medium_impact	0,7	0,5	0,9	18,14	12,08	N	0,35	N	0,57	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9478	9478	T	C	MI.7210	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	272	91	V	A	gTt/gCt	3,6	1	0	benign	0	neutral	0,36	neutral	2,01	neutral	-2,06	deleterious	-3,41	medium_impact	2,28	neutral	0,76	neutral	0,68	neutral	1,56	13,61	0,13	0,4	neutral	0,16	disease	0,62	disease	0,51	neutral	0,42	2	neutral	0,64	deleterious	0,68	neutral	-3	neutral	0,14	high_impact	2,05	medium_impact	0,05	medium_impact	0,86	0,17	0,8	26,05	16,97	P	0,59	P	0,37	disease_causing_automatic	0	0,11	rs587776437	Pathogenic	Leigh_syndrome	RCV000144007.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	CPD	1,34	T9478C	Leigh Disease	-	+	Reported	1
chrM	9480	9480	T	C	MI.7211	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	274	92	F	L	Ttt/Ctt	-16,07	0	0	probably_damaging	0,97	neutral	0,32	neutral	2,55	neutral	1,12	neutral	-0,35	low_impact	1,1	neutral	0,78	neutral	0,96	deleterious	0,46	7,12	0,22	0,45	neutral	0,15	neutral	0,46	neutral	0,3	neutral	0,45	1	neutral	0,97	neutral	0,18	neutral	-2	deleterious	0,63	low_impact	-2,34	medium_impact	0,01	medium_impact	-0,2	0,57	0,8	10,34	40,23	N	0,34	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9480	9480	T	G	MI.7212	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	274	92	F	V	Ttt/Gtt	-16,07	0	0	probably_damaging	0,98	neutral	0,3	neutral	2,34	neutral	0,2	neutral	-1,89	medium_impact	2,06	neutral	0,63	neutral	0,52	deleterious	3,49	23,1	0,15	0,4	neutral	0,1	disease	0,82	neutral	0,47	disease	0,62	2	deleterious	0,98	neutral	0,16	deleterious	1	deleterious	0,65	low_impact	-2,51	medium_impact	-0,02	medium_impact	0,66	0,17	0,8	10,34	40,23	N	0,39	N	0,88	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9480	9480	T	A	MI.7213	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	274	92	F	I	Ttt/Att	-16,07	0	0	probably_damaging	0,98	neutral	0,16	neutral	2,34	neutral	-0,06	neutral	-1,16	medium_impact	2,24	neutral	0,66	neutral	0,51	deleterious	2,6	20,2	0,15	0,4	neutral	0,15	disease	0,84	neutral	0,36	disease	0,73	5	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,68	low_impact	-2,51	medium_impact	-0,22	medium_impact	0,83	0,3	0,8	10,34	40,23	N	0,39	N	0,78	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9481	9481	T	A	MI.7214	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	275	92	F	Y	tTt/tAt	1,52	0,91	0	probably_damaging	0,97	neutral	0,2	neutral	2,21	neutral	-2	neutral	-1,49	high_impact	3,65	neutral	0,64	neutral	0,47	deleterious	3,88	23,5	0,21	0,45	neutral	0,34	disease	0,76	disease	0,57	disease	0,7	4	deleterious	0,98	neutral	0,12	deleterious	2	deleterious	0,7	low_impact	-2,34	medium_impact	-0,15	high_impact	2,09	0,41	0,8	10,34	40,23	N	0,4	N	0,73	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9481	9481	T	G	MI.7215	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	275	92	F	C	tTt/tGt	1,52	0,91	0	probably_damaging	1	neutral	0,07	neutral	2,22	neutral	-2,67	neutral	-1,69	neutral_impact	0,55	neutral	0,7	neutral	0,79	deleterious	2,61	20,3	0,1	0,4	neutral	0,46	disease	0,77	neutral	0,36	disease	0,52	0	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,71	low_impact	-3,78	medium_impact	-0,45	medium_impact	-0,69	0,13	0,8	10,34	40,23	N	0,34	N	0,96	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9481	9481	T	C	MI.7216	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	275	92	F	S	tTt/tCt	1,52	0,91	0	probably_damaging	0,99	neutral	0,17	neutral	2,23	neutral	-1,34	deleterious	-3,47	medium_impact	2,5	neutral	0,68	neutral	0,48	deleterious	3,92	23,5	0,06	0,35	neutral	0,28	disease	0,76	disease	0,56	disease	0,7	4	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,7	low_impact	-2,81	medium_impact	-0,2	medium_impact	1,06	0,26	0,8	10,34	40,23	N	0,34	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9482	9482	T	G	MI.7217	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	276	92	F	L	ttT/ttG	4,52	0,97	0	probably_damaging	0,97	neutral	0,32	neutral	2,55	neutral	1,12	neutral	-0,35	low_impact	1,1	neutral	0,78	neutral	0,96	deleterious	0,65	8,53	0,22	0,45	neutral	0,15	neutral	0,46	neutral	0,3	neutral	0,45	1	neutral	0,97	neutral	0,18	neutral	-2	deleterious	0,63	low_impact	-2,34	medium_impact	0,01	medium_impact	-0,2	0,57	0,8	10,34	40,23	N	0,46	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9482	9482	T	A	MI.7218	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	276	92	F	L	ttT/ttA	4,52	0,97	0	probably_damaging	0,97	neutral	0,32	neutral	2,55	neutral	1,12	neutral	-0,35	low_impact	1,1	neutral	0,78	neutral	0,96	deleterious	0,84	9,69	0,22	0,45	neutral	0,15	neutral	0,46	neutral	0,3	neutral	0,45	1	neutral	0,97	neutral	0,18	neutral	-2	deleterious	0,63	low_impact	-2,34	medium_impact	0,01	medium_impact	-0,2	0,57	0,8	10,34	40,23	N	0,47	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9483	9483	T	G	MI.7219	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	277	93	F	V	Ttc/Gtc	-1,03	0,01	0	benign	0,23	neutral	0,11	neutral	2,16	neutral	-1,44	deleterious	-6,21	medium_impact	3,21	neutral	0,66	damaging	0,02	deleterious	3,66	23,2	0,12	0,4	neutral	0,19	disease	0,87	disease	0,61	disease	0,67	3	neutral	0,87	neutral	0,44	neutral	-3	neutral	0,33	medium_impact	-0,36	medium_impact	-0,33	medium_impact	1,69	0,28	0,8	73,18	11,45	N	0,32	N	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8867	8867	T	G	MI.722	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	341	114	I	S	aTt/aGt	-1,03	0	0	benign	0,01	neutral	0,14	neutral	4,13	deleterious	-3,03	deleterious	-3,41	medium_impact	2,66	neutral	0,84	neutral	0,49	deleterious	2,25	17,82	0,24	0,65	disease	0,74	disease	0,85	disease	0,59	disease	0,65	3	neutral	0,86	deleterious	0,57	neutral	-3	neutral	0,28	medium_impact	1,14	medium_impact	-0,15	medium_impact	1,18	0,51	0,9	18,14	12,08	N	0,34	N	0,54	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9483	9483	T	C	MI.7220	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	277	93	F	L	Ttc/Ctc	-1,03	0,01	0	benign	0	neutral	0,3	neutral	2,32	neutral	-0,54	deleterious	-5,32	medium_impact	2,71	damaging	0,47	damaging	0,06	deleterious	1,99	16,12	0,18	0,45	neutral	0,1	disease	0,77	neutral	0,42	neutral	0,5	0	neutral	0,7	deleterious	0,65	neutral	-3	neutral	0,14	high_impact	2,05	medium_impact	-0,02	medium_impact	1,25	0,42	0,8	73,18	11,45	N	0,34	N	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9483	9483	T	A	MI.7221	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	277	93	F	I	Ttc/Atc	-1,03	0,01	0	benign	0,07	neutral	0,25	neutral	2,19	neutral	-1,58	deleterious	-5,33	medium_impact	2,67	neutral	0,7	damaging	0,02	deleterious	2,55	19,81	0,16	0,45	neutral	0,16	disease	0,86	disease	0,6	disease	0,53	1	neutral	0,72	deleterious	0,59	neutral	-3	neutral	0,33	medium_impact	0,22	medium_impact	-0,08	medium_impact	1,21	0,44	0,8	73,18	11,45	N	0,28	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9484	9484	T	C	MI.7222	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	278	93	F	S	tTc/tCc	7,53	1	0	possibly_damaging	0,69	neutral	0,08	neutral	2,04	deleterious	-3,62	deleterious	-6,89	high_impact	4,11	neutral	0,66	damaging	0,03	deleterious	4,05	23,7	0,05	0,35	neutral	0,32	disease	0,84	disease	0,61	disease	0,7	4	neutral	0,93	neutral	0,2	deleterious	1	deleterious	0,64	low_impact	-1,21	medium_impact	-0,41	high_impact	2,5	0,38	0,8	73,18	11,45	P	0,52	P	0,96	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9484	9484	T	A	MI.7223	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	278	93	F	Y	tTc/tAc	7,53	1	0	benign	0,26	deleterious	0,02	neutral	2,05	deleterious	-4,23	deleterious	-2,67	high_impact	4,65	neutral	0,7	damaging	0,03	deleterious	3,98	23,6	0,17	0,45	neutral	0,41	disease	0,83	disease	0,62	disease	0,69	4	neutral	0,98	neutral	0,38	deleterious	2	deleterious	0,51	medium_impact	-0,43	medium_impact	-0,77	high_impact	2,99	0,53	0,8	73,18	11,45	P	0,52	P	0,8	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9484	9484	T	G	MI.7224	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	278	93	F	C	tTc/tGc	7,53	1	0	probably_damaging	0,91	deleterious	0,02	neutral	2,02	deleterious	-4,99	deleterious	-6,88	high_impact	4,65	neutral	0,71	damaging	0,02	deleterious	3,98	23,6	0,07	0,35	disease	0,54	disease	0,9	disease	0,64	disease	0,72	4	deleterious	0,99	neutral	0,06	deleterious	6	deleterious	0,74	low_impact	-1,85	medium_impact	-0,77	high_impact	2,99	0,26	0,8	73,18	11,45	N	0,47	N	0,98	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9485	9485	C	A	MI.7225	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	279	93	F	L	ttC/ttA	7,53	1	0	benign	0	neutral	0,3	neutral	2,32	neutral	-0,54	deleterious	-5,32	medium_impact	2,71	damaging	0,47	damaging	0,06	deleterious	2,66	20,6	0,18	0,45	neutral	0,1	disease	0,77	neutral	0,42	neutral	0,5	0	neutral	0,7	deleterious	0,65	neutral	-3	neutral	0,14	high_impact	2,05	medium_impact	-0,02	medium_impact	1,25	0,42	0,8	73,18	11,45	P	0,52	P	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9485	9485	C	G	MI.7226	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	279	93	F	L	ttC/ttG	7,53	1	0	benign	0	neutral	0,3	neutral	2,32	neutral	-0,54	deleterious	-5,32	medium_impact	2,71	damaging	0,47	damaging	0,06	deleterious	2,37	18,62	0,18	0,45	neutral	0,1	disease	0,77	neutral	0,42	neutral	0,5	0	neutral	0,7	deleterious	0,65	neutral	-3	neutral	0,14	high_impact	2,05	medium_impact	-0,02	medium_impact	1,25	0,42	0,8	73,18	11,45	P	0,51	P	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9486	9486	T	G	MI.7227	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	280	94	F	V	Ttc/Gtc	-1,49	0	0	probably_damaging	1	deleterious	0,04	neutral	0,43	deleterious	-7,69	deleterious	-6,18	high_impact	4,79	neutral	0,66	damaging	0,02	deleterious	3,95	23,6	0,06	0,35	disease	0,56	disease	0,86	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,77	low_impact	-3,78	medium_impact	-0,6	high_impact	3,11	0,2	0,8	73,95	11,75	P	0,55	P	0,97	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9486	9486	T	C	MI.7228	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	280	94	F	L	Ttc/Ctc	-1,49	0	0	probably_damaging	0,98	neutral	0,14	neutral	0,49	deleterious	-5,79	deleterious	-5,34	high_impact	3,98	damaging	0,51	damaging	0,03	deleterious	3,93	23,5	0,05	0,35	neutral	0,27	disease	0,79	disease	0,63	disease	0,63	3	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,72	low_impact	-2,51	medium_impact	-0,26	high_impact	2,38	0,35	0,8	73,95	11,75	N	0,32	N	0,92	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9486	9486	T	A	MI.7229	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	280	94	F	I	Ttc/Atc	-1,49	0	0	probably_damaging	0,99	neutral	0,14	neutral	0,43	deleterious	-7,41	deleterious	-5,32	high_impact	4,79	neutral	0,69	damaging	0,02	deleterious	4,26	23,9	0,06	0,35	disease	0,53	disease	0,87	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,79	low_impact	-2,81	medium_impact	-0,26	high_impact	3,11	0,26	0,8	73,95	11,75	P	0,57	P	0,96	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8867	8867	T	A	MI.723	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	341	114	I	N	aTt/aAt	-1,03	0	0	benign	0,02	deleterious	0	neutral	4,11	deleterious	-4,24	deleterious	-4,75	high_impact	3,7	neutral	0,78	neutral	0,43	deleterious	2,43	19,04	0,22	0,65	disease	0,66	disease	0,87	disease	0,62	disease	0,74	5	deleterious	1	deleterious	0,49	deleterious	2	neutral	0,28	medium_impact	0,85	low_impact	-1,4	high_impact	2,07	0,61	0,9	18,14	12,08	N	0,37	N	0,82	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9487	9487	T	A	MI.7230	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	281	94	F	Y	tTc/tAc	5,91	1	0	probably_damaging	0,98	neutral	0,06	neutral	0,48	deleterious	-5,92	deleterious	-2,67	high_impact	4,44	neutral	0,7	damaging	0,03	deleterious	4,24	23,9	0,09	0,35	neutral	0,44	disease	0,81	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,76	low_impact	-2,51	medium_impact	-0,49	high_impact	2,8	0,44	0,8	73,95	11,75	P	0,56	P	0,8	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9487	9487	T	G	MI.7231	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	281	94	F	C	tTc/tGc	5,91	1	0	probably_damaging	1	deleterious	0	neutral	0,41	deleterious	-10,25	deleterious	-6,99	high_impact	4,79	neutral	0,71	damaging	0,02	deleterious	4,06	23,7	0,04	0,35	disease	0,89	disease	0,88	disease	0,72	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,78	low_impact	-1,52	high_impact	3,11	0,15	0,8	73,95	11,75	P	0,58	P	0,98	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9487	9487	T	C	MI.7232	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	281	94	F	S	tTc/tCc	5,91	1	0	probably_damaging	1	neutral	0,19	neutral	0,41	deleterious	-9,65	deleterious	-6,9	high_impact	4,44	neutral	0,69	damaging	0,03	deleterious	4,16	23,8	0,03	0,35	disease	0,78	disease	0,82	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,17	high_impact	2,8	0,17	0,8	73,95	11,75	N	0,5	N	0,96	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9488	9488	C	G	MI.7233	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	282	94	F	L	ttC/ttG	7,53	1	0	probably_damaging	0,98	neutral	0,14	neutral	0,49	deleterious	-5,79	deleterious	-5,34	high_impact	3,98	damaging	0,51	damaging	0,03	deleterious	4,29	24	0,05	0,35	neutral	0,27	disease	0,79	disease	0,63	disease	0,63	3	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,72	low_impact	-2,51	medium_impact	-0,26	high_impact	2,38	0,35	0,8	73,95	11,75	N	0,51	P	0,92	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9488	9488	C	A	MI.7234	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	282	94	F	L	ttC/ttA	7,53	1	0	probably_damaging	0,98	neutral	0,14	neutral	0,49	deleterious	-5,79	deleterious	-5,34	high_impact	3,98	damaging	0,51	damaging	0,03	deleterious	4,62	24,5	0,05	0,35	neutral	0,27	disease	0,79	disease	0,63	disease	0,63	3	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,72	low_impact	-2,51	medium_impact	-0,26	high_impact	2,38	0,35	0,8	73,95	11,75	N	0,52	P	0,92	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9489	9489	G	T	MI.7235	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	283	95	A	S	Gca/Tca	-2,65	0	0	benign	0,08	neutral	0,19	neutral	2,23	neutral	-1,37	neutral	-0,57	low_impact	1,45	neutral	0,74	neutral	0,89	deleterious	0,79	9,42	0,16	0,45	neutral	0,18	neutral	0,38	neutral	0,42	neutral	0,45	1	neutral	0,79	deleterious	0,56	neutral	-6	neutral	0,15	medium_impact	0,16	medium_impact	-0,17	medium_impact	0,12	0,34	0,8	18,39	37,46	N	0,49	N	0,05	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9489	9489	G	C	MI.7236	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	283	95	A	P	Gca/Cca	-2,65	0	0	benign	0,3	deleterious	0,01	neutral	2,19	neutral	-2,92	neutral	-2,06	medium_impact	2,64	damaging	0,55	neutral	0,32	deleterious	3,52	23,1	0,04	0,35	neutral	0,48	disease	0,79	disease	0,59	disease	0,76	5	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,57	medium_impact	-0,51	medium_impact	-0,95	medium_impact	1,18	0,43	0,8	18,39	37,46	N	0,29	N	0,76	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9489	9489	G	A	MI.7237	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	283	95	A	T	Gca/Aca	-2,65	0	0	benign	0	neutral	0,05	neutral	2,25	neutral	-0,9	neutral	-0,13	medium_impact	2,3	neutral	0,78	neutral	0,97	neutral	1,06	11	0,11	0,4	neutral	0,22	neutral	0,35	neutral	0,38	neutral	0,44	1	neutral	0,95	deleterious	0,53	neutral	-3	neutral	0,11	high_impact	2,05	medium_impact	-0,54	medium_impact	0,88	0,6	0,8	18,39	37,46	N	0,48	N	0,03	polymorphism	1	0,02	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	9490	9490	C	T	MI.7238	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	284	95	A	V	gCa/gTa	-1,26	0	0	benign	0	neutral	0,09	neutral	2,35	neutral	0,29	neutral	1,07	neutral_impact	0,73	neutral	0,77	neutral	0,78	neutral	1,2	11,72	0,09	0,35	neutral	0,15	neutral	0,28	neutral	0,24	neutral	0,43	1	neutral	0,91	deleterious	0,55	neutral	-6	neutral	0,09	high_impact	2,05	medium_impact	-0,38	medium_impact	-0,53	0,55	0,8	18,39	37,46	N	0,41	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9490	9490	C	G	MI.7239	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	284	95	A	G	gCa/gGa	-1,26	0	0	benign	0,16	neutral	0,12	neutral	2,2	neutral	-2,41	neutral	-2,11	low_impact	1,09	neutral	0,66	neutral	0,66	deleterious	2,12	16,96	0,14	0,4	neutral	0,23	neutral	0,47	neutral	0,41	neutral	0,49	0	neutral	0,86	deleterious	0,48	neutral	-6	neutral	0,25	medium_impact	-0,17	medium_impact	-0,3	medium_impact	-0,21	0,51	0,8	18,39	37,46	N	0,47	N	0,22	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8868	8868	T	A	MI.724	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	342	114	I	M	atT/atA	3,6	0,36	0	benign	0,07	neutral	0,14	neutral	4,14	neutral	-2,76	neutral	-1,41	medium_impact	2,02	neutral	0,91	neutral	0,67	neutral	1,77	14,79	0,37	0,65	disease	0,8	disease	0,57	neutral	0,41	disease	0,52	0	neutral	0,85	deleterious	0,54	neutral	-3	neutral	0,3	medium_impact	0,31	medium_impact	-0,15	medium_impact	0,63	0,76	0,9	18,14	12,08	N	0,37	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9490	9490	C	A	MI.7240	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	284	95	A	E	gCa/gAa	-1,26	0	0	benign	0,24	deleterious	0,01	neutral	2,21	neutral	-2,05	neutral	-1,71	medium_impact	2,99	neutral	0,63	neutral	0,58	deleterious	2,8	21,4	0,05	0,35	neutral	0,29	disease	0,67	disease	0,59	disease	0,71	4	deleterious	0,99	neutral	0,39	deleterious	1	neutral	0,32	medium_impact	-0,38	medium_impact	-0,95	medium_impact	1,5	0,41	0,8	18,39	37,46	N	0,42	N	0,7	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9492	9492	G	T	MI.7241	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	286	96	G	W	Gga/Tga	-10,75	0	0	probably_damaging	1	neutral	0,13	neutral	2,16	deleterious	-4,94	deleterious	-4,42	high_impact	3,58	damaging	0,58	damaging	0,15	deleterious	4,33	24	0,06	0,35	disease	0,77	disease	0,85	disease	0,61	disease	0,75	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	-0,28	high_impact	2,03	0,12	0,8	73,95	11,69	N	0,25	N	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9492	9492	G	C	MI.7242	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	286	96	G	R	Gga/Cga	-10,75	0	0	probably_damaging	1	neutral	0,12	neutral	2,2	neutral	-2	deleterious	-3,23	medium_impact	3,23	damaging	0,55	damaging	0,17	deleterious	3,89	23,5	0,05	0,35	neutral	0,31	disease	0,86	disease	0,61	disease	0,75	5	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	-0,3	medium_impact	1,71	0,41	0,8	73,95	11,69	N	0,31	N	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9493	9493	G	A	MI.7243	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	287	96	G	E	gGa/gAa	9,38	1	0	probably_damaging	1	neutral	0,11	neutral	2,21	neutral	-1,56	deleterious	-2,87	high_impact	3,58	damaging	0,56	damaging	0,19	deleterious	3,86	23,5	0,06	0,35	neutral	0,24	disease	0,79	disease	0,65	disease	0,73	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,72	low_impact	-3,78	medium_impact	-0,33	high_impact	2,03	0,25	0,8	73,95	11,69	P	0,52	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9493	9493	G	T	MI.7244	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	287	96	G	V	gGa/gTa	9,38	1	0	probably_damaging	1	neutral	0,28	neutral	2,22	neutral	-1,35	deleterious	-3,67	medium_impact	2,6	neutral	0,62	damaging	0,27	deleterious	3,69	23,3	0,09	0,35	neutral	0,31	disease	0,75	disease	0,55	disease	0,65	3	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,71	low_impact	-3,78	medium_impact	-0,04	medium_impact	1,15	0,13	0,8	73,95	11,69	P	0,48	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9493	9493	G	C	MI.7245	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	287	96	G	A	gGa/gCa	9,38	1	0	probably_damaging	1	neutral	0,19	neutral	2,45	neutral	0,89	neutral	-0,66	neutral_impact	-0,42	neutral	0,68	neutral	0,71	neutral	1,77	14,83	0,13	0,4	neutral	0,13	neutral	0,19	neutral	0,27	neutral	0,34	3	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,64	low_impact	-3,78	medium_impact	-0,17	low_impact	-1,56	0,38	0,8	73,95	11,69	P	0,59	P	0,3	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9495	9495	T	C	MI.7246	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	289	97	F	L	Ttt/Ctt	-12,37	0	0,01	probably_damaging	0,98	neutral	0,05	neutral	2,45	neutral	0,75	deleterious	-5,31	low_impact	1,84	damaging	0,57	neutral	0,58	deleterious	2,16	17,25	0,17	0,45	neutral	0,15	disease	0,72	disease	0,53	neutral	0,49	0	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,66	low_impact	-2,51	medium_impact	-0,54	medium_impact	0,47	0,36	0,8	72,8	11,81	N	0,39	N	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9495	9495	T	G	MI.7247	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	289	97	F	V	Ttt/Gtt	-12,37	0	0,01	probably_damaging	1	deleterious	0,02	neutral	2,29	neutral	-1,42	deleterious	-6,22	medium_impact	3,23	damaging	0,53	neutral	0,54	deleterious	3,92	23,5	0,09	0,4	neutral	0,2	disease	0,83	disease	0,61	disease	0,64	3	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,69	low_impact	-3,78	medium_impact	-0,77	medium_impact	1,71	0,2	0,8	72,8	11,81	N	0,41	N	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9495	9495	T	A	MI.7248	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	289	97	F	I	Ttt/Att	-12,37	0	0,01	probably_damaging	0,99	neutral	0,09	neutral	2,4	neutral	-1,28	deleterious	-5,34	medium_impact	2,81	neutral	0,6	neutral	0,58	deleterious	2,78	21,3	0,13	0,4	neutral	0,14	disease	0,79	disease	0,51	neutral	0,49	0	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,7	low_impact	-2,81	medium_impact	-0,38	medium_impact	1,34	0,32	0,8	72,8	11,81	N	0,41	N	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9496	9496	T	G	MI.7249	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	290	97	F	C	tTt/tGt	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	2,1	deleterious	-4,27	deleterious	-7,12	high_impact	4,55	neutral	0,64	neutral	0,45	deleterious	4,08	23,7	0,05	0,35	disease	0,6	disease	0,88	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-3,78	medium_impact	-0,95	high_impact	2,9	0,19	0,8	72,8	11,81	P	0,51	P	0,98	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8868	8868	T	G	MI.725	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	342	114	I	M	atT/atG	3,6	0,36	0	benign	0,07	neutral	0,14	neutral	4,14	neutral	-2,76	neutral	-1,41	medium_impact	2,02	neutral	0,91	neutral	0,67	neutral	1,45	13,05	0,37	0,65	disease	0,8	disease	0,57	neutral	0,41	disease	0,52	0	neutral	0,85	deleterious	0,54	neutral	-3	neutral	0,3	medium_impact	0,31	medium_impact	-0,15	medium_impact	0,63	0,76	0,9	18,14	12,08	N	0,37	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9496	9496	T	C	MI.7250	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	290	97	F	S	tTt/tCt	7,53	1	0	probably_damaging	1	neutral	0,39	neutral	2,12	neutral	-2,98	deleterious	-7,08	high_impact	3,86	neutral	0,7	neutral	0,62	deleterious	4,25	23,9	0,04	0,35	neutral	0,42	disease	0,81	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	0,08	high_impact	2,28	0,28	0,8	72,8	11,81	P	0,56	P	0,96	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9496	9496	T	A	MI.7251	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	290	97	F	Y	tTt/tAt	7,53	1	0	probably_damaging	0,98	deleterious	0,04	neutral	2,12	neutral	-2,74	deleterious	-2,69	high_impact	4	neutral	0,65	neutral	0,42	deleterious	4,36	24,1	0,15	0,4	neutral	0,29	disease	0,79	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,72	low_impact	-2,51	medium_impact	-0,6	high_impact	2,4	0,46	0,8	72,8	11,81	P	0,6	P	0,8	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9497	9497	T	G	MI.7252	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	291	97	F	L	ttT/ttG	7,53	1	0	probably_damaging	0,98	neutral	0,05	neutral	2,45	neutral	0,75	deleterious	-5,31	low_impact	1,84	damaging	0,57	neutral	0,58	deleterious	2,22	17,64	0,17	0,45	neutral	0,15	disease	0,72	disease	0,53	neutral	0,49	0	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,66	low_impact	-2,51	medium_impact	-0,54	medium_impact	0,47	0,36	0,8	72,8	11,81	P	0,53	P	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9497	9497	T	A	MI.7253	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	291	97	F	L	ttT/ttA	7,53	1	0	probably_damaging	0,98	neutral	0,05	neutral	2,45	neutral	0,75	deleterious	-5,31	low_impact	1,84	damaging	0,57	neutral	0,58	deleterious	2,41	18,91	0,17	0,45	neutral	0,15	disease	0,72	disease	0,53	neutral	0,49	0	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,66	low_impact	-2,51	medium_impact	-0,54	medium_impact	0,47	0,36	0,8	72,8	11,81	P	0,54	P	0,92	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9498	9498	T	C	MI.7254	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	292	98	F	L	Ttc/Ctc	-4,04	0	0	probably_damaging	0,98	neutral	0,12	neutral	1,95	neutral	-2,04	deleterious	-5,25	medium_impact	2,81	damaging	0,54	neutral	0,61	deleterious	3,89	23,5	0,1	0,4	neutral	0,34	disease	0,76	disease	0,64	disease	0,61	2	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,73	low_impact	-2,51	medium_impact	-0,3	medium_impact	1,34	0,34	0,8	73,95	11,7	N	0,36	N	0,92	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9498	9498	T	A	MI.7255	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	292	98	F	I	Ttc/Atc	-4,04	0	0	probably_damaging	0,98	deleterious	0,02	neutral	1,85	neutral	-2,72	deleterious	-5,31	medium_impact	3,5	neutral	0,68	neutral	0,62	deleterious	4,26	23,9	0,1	0,4	disease	0,52	disease	0,85	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,78	low_impact	-2,51	medium_impact	-0,77	medium_impact	1,95	0,39	0,8	73,95	11,7	N	0,35	N	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9498	9498	T	G	MI.7256	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	292	98	F	V	Ttc/Gtc	-4,04	0	0	probably_damaging	0,99	neutral	0,06	neutral	1,74	deleterious	-4	deleterious	-6,24	high_impact	4,19	damaging	0,58	neutral	0,54	deleterious	3,96	23,6	0,07	0,35	disease	0,51	disease	0,84	disease	0,71	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,76	low_impact	-2,81	medium_impact	-0,49	high_impact	2,57	0,29	0,8	73,95	11,7	N	0,4	N	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9499	9499	T	G	MI.7257	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	293	98	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	1,68	deleterious	-7,21	deleterious	-7,22	high_impact	4,74	neutral	0,61	neutral	0,46	deleterious	4	23,6	0,05	0,35	disease	0,84	disease	0,86	disease	0,73	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-3,78	medium_impact	-0,95	high_impact	3,07	0,23	0,8	73,95	11,7	P	0,59	P	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9499	9499	T	C	MI.7258	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	293	98	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	neutral	0,16	neutral	1,68	deleterious	-6,5	deleterious	-7,23	high_impact	4,74	neutral	0,71	neutral	0,63	deleterious	4,17	23,8	0,05	0,35	disease	0,64	disease	0,81	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	-0,22	high_impact	3,07	0,39	0,8	73,95	11,7	P	0,65	P	0,96	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9499	9499	T	A	MI.7259	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	293	98	F	Y	tTc/tAc	7,53	1	0	probably_damaging	0,98	neutral	0,1	neutral	1,7	deleterious	-5,24	deleterious	-2,72	high_impact	4,74	neutral	0,64	neutral	0,42	deleterious	4,16	23,8	0,1	0,4	neutral	0,42	disease	0,78	disease	0,69	disease	0,68	4	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,75	low_impact	-2,51	medium_impact	-0,35	high_impact	3,07	0,43	0,8	73,95	11,7	P	0,68	P	0,8	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8869	8869	A	G	MI.726	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	343	115	M	V	Ata/Gta	-4,73	0	0,02	benign	0	neutral	0,37	neutral	4,47	neutral	1,07	neutral	0,29	neutral_impact	0,38	neutral	0,95	neutral	0,95	neutral	-0,43	0,33	0,59	0,7	neutral	0,42	disease	0,57	neutral	0,42	neutral	0,39	2	neutral	0,63	deleterious	0,69	neutral	-6	neutral	0,17	high_impact	2,09	medium_impact	0,16	medium_impact	-0,77	0,35	0,9	21,24	12,41	N	0,28	N	0,02	polymorphism	1	0,01	rs41432347	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9500	9500	C	A	MI.7260	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	294	98	F	L	ttC/ttA	7,53	1	0	probably_damaging	0,98	neutral	0,12	neutral	1,95	neutral	-2,04	deleterious	-5,25	medium_impact	2,81	damaging	0,54	neutral	0,61	deleterious	4,54	24,3	0,1	0,4	neutral	0,34	disease	0,76	disease	0,64	disease	0,61	2	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,73	low_impact	-2,51	medium_impact	-0,3	medium_impact	1,34	0,34	0,8	73,95	11,7	P	0,54	P	0,92	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9500	9500	C	G	MI.7261	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	294	98	F	L	ttC/ttG	7,53	1	0	probably_damaging	0,98	neutral	0,12	neutral	1,95	neutral	-2,04	deleterious	-5,25	medium_impact	2,81	damaging	0,54	neutral	0,61	deleterious	4,3	24	0,1	0,4	neutral	0,34	disease	0,76	disease	0,64	disease	0,61	2	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,73	low_impact	-2,51	medium_impact	-0,3	medium_impact	1,34	0,34	0,8	73,95	11,7	P	0,54	P	0,92	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9501	9501	T	C	MI.7262	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	295	99	W	R	Tga/Cga	0,82	1	0	probably_damaging	1	deleterious	0,02	neutral	2,03	neutral	-2,47	deleterious	-12,55	medium_impact	3,42	damaging	0,59	damaging	0,02	deleterious	3,53	23,1	0,04	0,35	neutral	0,44	disease	0,91	disease	0,79	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,8	low_impact	-3,78	medium_impact	-0,77	medium_impact	1,88	0,13	0,8	74,71	11,56	N	0,42	N	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9501	9501	T	G	MI.7263	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	295	99	W	G	Tga/Gga	0,82	1	0	probably_damaging	0,99	deleterious	0,02	neutral	1,99	deleterious	-3,45	deleterious	-11,65	low_impact	1,86	neutral	0,62	damaging	0,02	deleterious	3,85	23,4	0,06	0,35	neutral	0,34	disease	0,86	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,74	low_impact	-2,81	medium_impact	-0,77	medium_impact	0,48	0,14	0,8	74,71	11,56	N	0,31	N	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9502	9502	G	T	MI.7264	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	296	99	W	L	tGa/tTa	7,53	1	0	probably_damaging	0,99	neutral	0,16	neutral	2,08	neutral	-1,76	deleterious	-11,52	high_impact	3,55	neutral	0,63	damaging	0,03	deleterious	4,23	23,9	0,08	0,35	neutral	0,2	disease	0,86	disease	0,7	disease	0,73	5	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,73	low_impact	-2,81	medium_impact	-0,22	medium_impact	2	0,09	0,8	74,71	11,56	N	0,46	N	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9502	9502	G	C	MI.7265	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	296	99	W	S	tGa/tCa	7,53	1	0	probably_damaging	1	neutral	0,1	neutral	2,03	neutral	-2,5	deleterious	-12,43	medium_impact	3,33	neutral	0,66	damaging	0,03	deleterious	3,96	23,6	0,06	0,35	neutral	0,29	disease	0,9	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	-0,35	medium_impact	1,8	0,17	0,8	74,71	11,56	N	0,42	N	0,97	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9503	9503	A	T	MI.7266	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	297	99	W	C	tgA/tgT	9,15	1	0	probably_damaging	1	deleterious	0,01	neutral	2	deleterious	-3,43	deleterious	-11,66	high_impact	3,98	neutral	0,67	damaging	0,02	deleterious	4,08	23,7	0,06	0,35	neutral	0,27	disease	0,91	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,75	low_impact	-3,78	medium_impact	-0,95	high_impact	2,38	0,11	0,8	74,71	11,56	N	0,45	N	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9503	9503	A	C	MI.7267	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	297	99	W	C	tgA/tgC	9,15	1	0	probably_damaging	1	deleterious	0,01	neutral	2	deleterious	-3,43	deleterious	-11,66	high_impact	3,98	neutral	0,67	damaging	0,02	deleterious	3,98	23,6	0,06	0,35	neutral	0,27	disease	0,91	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,75	low_impact	-3,78	medium_impact	-0,95	high_impact	2,38	0,11	0,8	74,71	11,56	N	0,45	N	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9504	9504	G	C	MI.7268	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	298	100	A	P	Gcc/Ccc	3,37	1	0	probably_damaging	1	deleterious	0,02	neutral	1,8	deleterious	-4,35	deleterious	-4	high_impact	4,48	neutral	0,62	damaging	0,02	deleterious	3,79	23,4	0,03	0,35	disease	0,55	disease	0,89	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,78	medium_impact	-0,77	high_impact	2,83	0,55	0,8	74,71	11,47	N	0,49	N	0,99	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9504	9504	G	A	MI.7269	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	298	100	A	T	Gcc/Acc	3,37	1	0	probably_damaging	0,99	neutral	0,07	neutral	1,98	neutral	-1,52	deleterious	-2,6	medium_impact	2,05	damaging	0,47	damaging	0,06	deleterious	3,06	22,4	0,1	0,4	neutral	0,21	disease	0,73	neutral	0,34	neutral	0,47	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,72	low_impact	-2,81	medium_impact	-0,45	medium_impact	0,66	0,63	0,8	74,71	11,47	P	0,52	P	0,86	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8869	8869	A	C	MI.727	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	343	115	M	L	Ata/Cta	-4,73	0	0,02	benign	0	neutral	0,87	neutral	4,55	neutral	1,7	neutral	0,07	neutral_impact	-0,88	neutral	0,91	neutral	0,98	neutral	-0,29	0,69	0,52	0,65	neutral	0,42	neutral	0,47	neutral	0,35	neutral	0,45	1	neutral	0,11	deleterious	0,94	neutral	-6	neutral	0,17	high_impact	2,09	medium_impact	0,76	low_impact	-1,85	0,48	0,9	21,24	12,41	N	0,32	N	0,03	polymorphism	1	0,01	rs41432347	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9504	9504	G	T	MI.7270	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	298	100	A	S	Gcc/Tcc	3,37	1	0	probably_damaging	0,99	neutral	0,06	neutral	1,89	neutral	-2,41	neutral	-1,89	medium_impact	2,46	damaging	0,47	damaging	0,07	deleterious	3,62	23,2	0,18	0,45	neutral	0,26	disease	0,71	neutral	0,32	neutral	0,47	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,73	low_impact	-2,81	medium_impact	-0,49	medium_impact	1,02	0,39	0,8	74,71	11,47	P	0,52	P	0,89	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9505	9505	C	T	MI.7271	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	299	100	A	V	gCc/gTc	6,14	1	0	probably_damaging	0,99	neutral	0,05	neutral	1,84	deleterious	-3,08	deleterious	-3,26	medium_impact	3,28	damaging	0,57	damaging	0,02	deleterious	4,39	24,1	0,07	0,35	neutral	0,38	disease	0,85	disease	0,56	disease	0,63	3	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,75	low_impact	-2,81	medium_impact	-0,54	medium_impact	1,76	0,67	0,85	74,71	11,47	N	0,48	N	0,87	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9505	9505	C	G	MI.7272	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	299	100	A	G	gCc/gGc	6,14	1	0	probably_damaging	0,98	neutral	0,12	neutral	1,83	deleterious	-3,25	deleterious	-2,72	medium_impact	2,13	damaging	0,48	damaging	0,07	deleterious	2,82	21,5	0,17	0,45	neutral	0,29	disease	0,75	neutral	0,32	neutral	0,48	1	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,71	low_impact	-2,51	medium_impact	-0,3	medium_impact	0,73	0,57	0,8	74,71	11,47	P	0,49	N	0,67	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9505	9505	C	A	MI.7273	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	299	100	A	D	gCc/gAc	6,14	1	0	probably_damaging	1	deleterious	0,02	neutral	1,8	deleterious	-4,15	deleterious	-4,57	high_impact	4,48	neutral	0,64	damaging	0,01	deleterious	4,59	24,4	0,02	0,35	neutral	0,32	disease	0,92	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-3,78	medium_impact	-0,77	high_impact	2,83	0,35	0,8	74,71	11,47	N	0,46	N	0,99	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9507	9507	T	C	MI.7274	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	301	101	F	L	Ttt/Ctt	-14,68	0	0	probably_damaging	0,97	neutral	0,24	neutral	1,84	neutral	-2,71	deleterious	-4,58	low_impact	1,76	neutral	0,6	damaging	0,15	deleterious	2,85	21,6	0,14	0,4	neutral	0,16	disease	0,72	disease	0,58	disease	0,51	0	neutral	0,98	neutral	0,14	neutral	-2	deleterious	0,68	low_impact	-2,34	medium_impact	-0,09	medium_impact	0,4	0,33	0,8	74,71	11,68	N	0,26	N	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9507	9507	T	A	MI.7275	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	301	101	F	I	Ttt/Att	-14,68	0	0	probably_damaging	0,98	neutral	0,08	neutral	1,8	deleterious	-3,49	deleterious	-4,75	high_impact	3,93	neutral	0,68	damaging	0,05	deleterious	4,33	24	0,12	0,4	neutral	0,19	disease	0,83	disease	0,66	disease	0,7	4	deleterious	0,99	neutral	0,05	deleterious	2	deleterious	0,7	low_impact	-2,51	medium_impact	-0,41	high_impact	2,34	0,32	0,8	74,71	11,68	N	0,3	N	0,96	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9507	9507	T	G	MI.7276	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	301	101	F	V	Ttt/Gtt	-14,68	0	0	probably_damaging	0,99	neutral	0,1	neutral	1,81	deleterious	-3,29	deleterious	-5,58	high_impact	4,28	neutral	0,67	damaging	0,04	deleterious	4,01	23,6	0,08	0,35	neutral	0,2	disease	0,83	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,68	low_impact	-2,81	medium_impact	-0,35	high_impact	2,65	0,25	0,8	74,71	11,68	N	0,31	N	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9508	9508	T	G	MI.7277	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	302	101	F	C	tTt/tGt	7,53	1	0	probably_damaging	1	deleterious	0,04	neutral	1,75	deleterious	-5,74	deleterious	-6,62	high_impact	3,73	neutral	0,72	damaging	0,03	deleterious	4	23,6	0,05	0,35	neutral	0,37	disease	0,87	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,73	low_impact	-3,78	medium_impact	-0,6	high_impact	2,16	0,2	0,8	74,71	11,68	N	0,41	N	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9508	9508	T	C	MI.7278	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	302	101	F	S	tTt/tCt	7,53	1	0	probably_damaging	1	neutral	0,21	neutral	1,81	deleterious	-3,41	deleterious	-6,66	medium_impact	3,31	damaging	0,59	damaging	0,04	deleterious	4,07	23,7	0,03	0,35	neutral	0,26	disease	0,78	disease	0,66	disease	0,62	2	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	-0,14	medium_impact	1,78	0,35	0,8	74,71	11,68	N	0,45	N	0,96	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9508	9508	T	A	MI.7279	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	302	101	F	Y	tTt/tAt	7,53	1	0	probably_damaging	0,97	neutral	0,24	neutral	2,02	neutral	-1,21	neutral	-2,15	neutral_impact	0,6	damaging	0,55	damaging	0,09	deleterious	4,02	23,6	0,16	0,45	neutral	0,11	disease	0,53	neutral	0,43	neutral	0,41	2	neutral	0,98	neutral	0,14	neutral	-2	deleterious	0,67	low_impact	-2,34	medium_impact	-0,09	medium_impact	-0,65	0,48	0,8	74,71	11,68	P	0,53	P	0,8	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8869	8869	A	T	MI.728	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	343	115	M	L	Ata/Tta	-4,73	0	0,02	benign	0	neutral	0,87	neutral	4,55	neutral	1,7	neutral	0,07	neutral_impact	-0,88	neutral	0,91	neutral	0,98	neutral	-0,22	0,98	0,52	0,65	neutral	0,42	neutral	0,47	neutral	0,35	neutral	0,45	1	neutral	0,11	deleterious	0,94	neutral	-6	neutral	0,17	high_impact	2,09	medium_impact	0,76	low_impact	-1,85	0,48	0,9	21,24	12,41	N	0,32	N	0,03	polymorphism	1	0,01	rs41432347	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9509	9509	T	G	MI.7280	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	303	101	F	L	ttT/ttG	7,53	1	0	probably_damaging	0,97	neutral	0,24	neutral	1,84	neutral	-2,71	deleterious	-4,58	low_impact	1,76	neutral	0,6	damaging	0,15	deleterious	3,2	22,7	0,14	0,4	neutral	0,16	disease	0,72	disease	0,58	disease	0,51	0	neutral	0,98	neutral	0,14	neutral	-2	deleterious	0,68	low_impact	-2,34	medium_impact	-0,09	medium_impact	0,4	0,33	0,8	74,71	11,68	N	0,5	N	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9509	9509	T	A	MI.7281	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	303	101	F	L	ttT/ttA	7,53	1	0	probably_damaging	0,97	neutral	0,24	neutral	1,84	neutral	-2,71	deleterious	-4,58	low_impact	1,76	neutral	0,6	damaging	0,15	deleterious	3,3	22,9	0,14	0,4	neutral	0,16	disease	0,72	disease	0,58	disease	0,51	0	neutral	0,98	neutral	0,14	neutral	-2	deleterious	0,68	low_impact	-2,34	medium_impact	-0,09	medium_impact	0,4	0,33	0,8	74,71	11,68	N	0,5	N	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9510	9510	T	C	MI.7282	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	304	102	Y	H	Tac/Cac	-4,27	0	0	probably_damaging	1	neutral	0,57	neutral	2,19	neutral	-2,28	deleterious	-3,97	medium_impact	2,6	damaging	0,48	damaging	0,03	deleterious	3,5	23,1	0,11	0,4	neutral	0,48	disease	0,65	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,29	deleterious	1	deleterious	0,75	low_impact	-3,78	medium_impact	0,26	medium_impact	1,15	0,33	0,8	74,71	11,6	N	0,23	N	0,97	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9510	9510	T	G	MI.7283	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	304	102	Y	D	Tac/Gac	-4,27	0	0	probably_damaging	1	neutral	0,11	neutral	2,17	deleterious	-3,05	deleterious	-6,52	medium_impact	2,6	damaging	0,45	damaging	0,02	deleterious	3,85	23,4	0,04	0,35	disease	0,56	disease	0,82	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,8	low_impact	-3,78	medium_impact	-0,33	medium_impact	1,15	0,22	0,8	74,71	11,6	N	0,26	N	0,99	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9510	9510	T	A	MI.7284	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	304	102	Y	N	Tac/Aac	-4,27	0	0	probably_damaging	1	neutral	0,1	neutral	2,18	neutral	-2,57	deleterious	-6,25	medium_impact	2,6	damaging	0,52	damaging	0,04	deleterious	3,92	23,5	0,05	0,35	neutral	0,45	disease	0,84	disease	0,61	disease	0,75	5	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,78	low_impact	-3,78	medium_impact	-0,35	medium_impact	1,15	0,33	0,8	74,71	11,6	N	0,24	N	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9511	9511	A	G	MI.7285	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	305	102	Y	C	tAc/tGc	7,53	1	0	probably_damaging	1	neutral	0,06	neutral	2,17	deleterious	-3,67	deleterious	-5,53	medium_impact	2,6	damaging	0,48	damaging	0,02	deleterious	3,53	23,1	0,04	0,35	disease	0,52	disease	0,85	disease	0,62	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	-0,49	medium_impact	1,15	0,27	0,8	74,71	11,6	N	0,41	N	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9511	9511	A	C	MI.7286	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	305	102	Y	S	tAc/tCc	7,53	1	0	probably_damaging	0,99	neutral	0,81	neutral	2,22	neutral	-1,32	deleterious	-5,54	low_impact	1,46	damaging	0,51	damaging	0,05	deleterious	3,68	23,3	0,06	0,35	neutral	0,23	disease	0,67	disease	0,6	disease	0,64	3	deleterious	0,99	neutral	0,41	neutral	-2	deleterious	0,71	low_impact	-2,81	medium_impact	0,55	medium_impact	0,13	0,32	0,8	74,71	11,6	N	0,39	N	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9511	9511	A	T	MI.7287	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	305	102	Y	F	tAc/tTc	7,53	1	0	probably_damaging	0,96	neutral	1	neutral	2,79	neutral	2,14	neutral	1,1	neutral_impact	-1,86	neutral	0,61	neutral	0,35	neutral	1,32	12,38	0,23	0,45	neutral	0,12	neutral	0,09	neutral	0,23	neutral	0,27	5	neutral	0,96	deleterious	0,52	neutral	-2	deleterious	0,59	low_impact	-2,21	high_impact	1,9	low_impact	-2,85	0,5	0,8	74,71	11,6	P	0,5	N	0,72	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9513	9513	C	T	MI.7288	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	307	103	H	Y	Cac/Tac	-2,88	0	0	probably_damaging	0,98	neutral	0,76	neutral	2	deleterious	-3,88	deleterious	-4,51	low_impact	1,72	damaging	0,55	damaging	0,03	deleterious	3,66	23,2	0,2	0,45	neutral	0,42	disease	0,82	disease	0,63	neutral	0,49	0	deleterious	0,98	neutral	0,39	neutral	-2	deleterious	0,77	low_impact	-2,51	medium_impact	0,48	medium_impact	0,36	0,18	0,8	73,56	11,77	N	0,14	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9513	9513	C	G	MI.7289	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	307	103	H	D	Cac/Gac	-2,88	0	0	probably_damaging	0,99	neutral	0,15	neutral	2,14	neutral	-1,19	deleterious	-7,53	medium_impact	2,37	damaging	0,55	damaging	0,02	deleterious	3,81	23,4	0,05	0,35	neutral	0,29	disease	0,78	disease	0,74	disease	0,52	0	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,74	low_impact	-2,81	medium_impact	-0,24	medium_impact	0,94	0,32	0,8	73,56	11,77	N	0,25	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8870	8870	T	C	MI.729	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	344	115	M	T	aTa/aCa	-0,1	0	0	benign	0	neutral	0,53	neutral	4,46	neutral	0,89	neutral	0,15	neutral_impact	-0,57	neutral	0,91	neutral	0,97	neutral	-0,86	0,03	0,48	0,65	neutral	0,27	neutral	0,33	neutral	0,39	neutral	0,43	1	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,14	high_impact	2,09	medium_impact	0,32	low_impact	-1,59	0,23	0,9	21,24	12,41	N	0,25	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9513	9513	C	A	MI.7290	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	307	103	H	N	Cac/Aac	-2,88	0	0	probably_damaging	0,99	neutral	0,28	neutral	2,07	neutral	-1,96	deleterious	-5,69	medium_impact	2,51	damaging	0,58	damaging	0,27	deleterious	2,8	21,4	0,22	0,45	neutral	0,31	disease	0,79	disease	0,65	neutral	0,48	0	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,73	low_impact	-2,81	medium_impact	-0,04	medium_impact	1,07	0,35	0,8	73,56	11,77	N	0,26	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9514	9514	A	T	MI.7291	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	308	103	H	L	cAc/cTc	5,45	1	0	probably_damaging	0,98	neutral	0,6	neutral	2,02	deleterious	-3,08	deleterious	-9,01	medium_impact	3,26	damaging	0,53	damaging	0,03	deleterious	3,81	23,4	0,06	0,35	neutral	0,22	disease	0,89	disease	0,69	disease	0,72	4	deleterious	0,98	neutral	0,31	deleterious	1	deleterious	0,73	low_impact	-2,51	medium_impact	0,29	medium_impact	1,74	0,17	0,8	73,56	11,77	N	0,4	N	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9514	9514	A	C	MI.7292	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	308	103	H	P	cAc/cCc	5,45	1	0	probably_damaging	1	neutral	0,15	neutral	2,01	deleterious	-3,7	deleterious	-8,53	high_impact	4,3	damaging	0,54	damaging	0,05	deleterious	3,18	22,7	0,04	0,35	neutral	0,46	disease	0,89	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	-0,24	high_impact	2,67	0,17	0,8	73,56	11,77	P	0,57	P	0,98	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9514	9514	A	G	MI.7293	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	308	103	H	R	cAc/cGc	5,45	1	0	probably_damaging	0,98	neutral	0,25	neutral	2,04	neutral	-2,51	deleterious	-6,74	high_impact	4,3	damaging	0,57	damaging	0,09	deleterious	2,93	22	0,1	0,4	neutral	0,3	disease	0,86	disease	0,73	disease	0,64	3	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,76	low_impact	-2,51	medium_impact	-0,08	high_impact	2,67	0,28	0,8	73,56	11,77	P	0,5	N	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9515	9515	C	G	MI.7294	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	309	103	H	Q	caC/caG	8,69	1	0	probably_damaging	0,99	neutral	0,22	neutral	2,06	neutral	-2,28	deleterious	-6,7	high_impact	3,75	damaging	0,58	damaging	0,03	deleterious	3,55	23,1	0,11	0,4	neutral	0,29	disease	0,79	disease	0,64	disease	0,66	3	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,72	low_impact	-2,81	medium_impact	-0,12	high_impact	2,18	0,37	0,8	73,56	11,77	N	0,44	N	0,94	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9515	9515	C	A	MI.7295	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	309	103	H	Q	caC/caA	8,69	1	0	probably_damaging	0,99	neutral	0,22	neutral	2,06	neutral	-2,28	deleterious	-6,7	high_impact	3,75	damaging	0,58	damaging	0,03	deleterious	3,77	23,4	0,11	0,4	neutral	0,29	disease	0,79	disease	0,64	disease	0,66	3	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,72	low_impact	-2,81	medium_impact	-0,12	high_impact	2,18	0,37	0,8	73,56	11,77	N	0,45	N	0,94	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9516	9516	T	C	MI.7296	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	310	104	S	P	Tcc/Ccc	0,13	0,98	0	probably_damaging	1	neutral	0,22	neutral	1,88	deleterious	-4,04	deleterious	-4,05	high_impact	3,9	damaging	0,43	damaging	0,04	deleterious	4,02	23,6	0,05	0,35	disease	0,51	disease	0,87	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,12	high_impact	2,31	0,26	0,8	75,1	11,72	P	0,55	P	0,98	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9516	9516	T	A	MI.7297	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	310	104	S	T	Tcc/Acc	0,13	0,98	0	probably_damaging	0,96	neutral	0,39	neutral	1,94	neutral	-2,64	neutral	-2,13	medium_impact	3	damaging	0,44	damaging	0,06	deleterious	3,97	23,6	0,21	0,45	neutral	0,26	disease	0,69	disease	0,57	disease	0,64	3	neutral	0,96	neutral	0,22	deleterious	1	deleterious	0,61	low_impact	-2,21	medium_impact	0,08	medium_impact	1,51	0,48	0,8	75,1	11,72	P	0,5	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9516	9516	T	G	MI.7298	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	310	104	S	A	Tcc/Gcc	0,13	0,98	0	probably_damaging	0,98	neutral	0,52	neutral	2,03	neutral	-1,51	neutral	-2,11	low_impact	1,39	damaging	0,6	neutral	0,36	deleterious	2,45	19,13	0,24	0,45	neutral	0,16	neutral	0,4	neutral	0,27	neutral	0,41	2	neutral	0,97	neutral	0,27	neutral	-2	deleterious	0,65	low_impact	-2,51	medium_impact	0,21	medium_impact	0,06	0,28	0,8	75,1	11,72	N	0,41	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9517	9517	C	T	MI.7299	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	311	104	S	F	tCc/tTc	2,21	1	0	probably_damaging	1	neutral	0,73	neutral	1,87	deleterious	-4,89	deleterious	-4,5	low_impact	1,94	damaging	0,41	damaging	0,03	deleterious	4,24	23,9	0,06	0,35	neutral	0,18	disease	0,88	neutral	0,39	neutral	0,39	2	deleterious	1	neutral	0,37	neutral	-2	deleterious	0,72	low_impact	-3,78	medium_impact	0,44	medium_impact	0,56	0,09	0,8	75,1	11,72	N	0,44	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8558	8558	C	A	MI.73	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	32	11	A	D	gCc/gAc	1,05	0,01	0	possibly_damaging	0,48	neutral	0,11	neutral	4,65	neutral	-0,81	neutral	-1,68	neutral_impact	0	neutral	0,8	neutral	0,43	deleterious	3,94	23,5	0,27	0,65	disease	0,51	disease	0,82	disease	0,56	disease	0,73	5	neutral	0,88	neutral	0,32	neutral	-3	deleterious	0,61	medium_impact	-0,72	medium_impact	-0,22	low_impact	-1,1	0,42	0,9	23,45	19,76	N	0,33	N	0,8	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8870	8870	T	A	MI.730	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	344	115	M	K	aTa/aAa	-0,1	0	0	benign	0,01	neutral	0,18	neutral	4,34	neutral	-1,43	deleterious	-2,66	low_impact	1,12	neutral	0,86	neutral	0,76	deleterious	1,95	15,9	0,33	0,65	disease	0,67	disease	0,81	disease	0,66	disease	0,72	4	neutral	0,82	deleterious	0,59	neutral	-6	neutral	0,29	medium_impact	1,14	medium_impact	-0,08	medium_impact	-0,14	0,56	0,9	21,24	12,41	N	0,29	N	0,69	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9517	9517	C	G	MI.7300	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	311	104	S	C	tCc/tGc	2,21	1	0	probably_damaging	1	neutral	0,18	neutral	1,87	deleterious	-5	deleterious	-3,8	medium_impact	3	damaging	0,43	damaging	0,03	deleterious	3,56	23,1	0,06	0,35	disease	0,53	disease	0,85	disease	0,57	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,75	low_impact	-3,78	medium_impact	-0,18	medium_impact	1,51	0,25	0,8	75,1	11,72	N	0,44	N	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9517	9517	C	A	MI.7301	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	311	104	S	Y	tCc/tAc	2,21	1	0	probably_damaging	1	neutral	1	neutral	1,87	deleterious	-4,91	deleterious	-4,58	medium_impact	2,37	damaging	0,41	damaging	0,03	deleterious	4,06	23,7	0,05	0,35	neutral	0,3	disease	0,87	disease	0,62	disease	0,63	3	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,75	low_impact	-3,78	high_impact	1,9	medium_impact	0,94	0,18	0,8	75,1	11,72	N	0,44	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9519	9519	A	G	MI.7302	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	313	105	S	G	Agc/Ggc	-5,66	0	0	probably_damaging	0,99	neutral	0,32	neutral	1,98	neutral	-2,66	deleterious	-3,8	medium_impact	3,12	damaging	0,48	damaging	0,17	deleterious	3,59	23,2	0,12	0,4	neutral	0,26	disease	0,65	disease	0,62	disease	0,64	3	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,69	low_impact	-2,81	medium_impact	0,01	medium_impact	1,61	0,5	0,8	73,18	11,71	N	0,34	N	0,83	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9519	9519	A	C	MI.7303	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	313	105	S	R	Agc/Cgc	-5,66	0	0	probably_damaging	1	neutral	0,34	neutral	1,94	deleterious	-3,57	deleterious	-4,75	low_impact	1,75	damaging	0,51	damaging	0,04	deleterious	3,82	23,4	0,09	0,35	neutral	0,12	disease	0,88	disease	0,6	disease	0,65	3	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,73	low_impact	-3,78	medium_impact	0,03	medium_impact	0,39	0,26	0,8	73,18	11,71	N	0,22	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9519	9519	A	T	MI.7304	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	313	105	S	C	Agc/Tgc	-5,66	0	0	probably_damaging	1	neutral	0,19	neutral	1,93	deleterious	-4,47	deleterious	-4,77	medium_impact	3,24	damaging	0,49	damaging	0,05	deleterious	3,46	23	0,06	0,35	neutral	0,41	disease	0,85	neutral	0,5	disease	0,7	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	-0,17	medium_impact	1,72	0,17	0,8	73,18	11,71	N	0,29	N	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9520	9520	G	T	MI.7305	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	314	105	S	I	aGc/aTc	8,69	1	0	probably_damaging	1	neutral	0,45	neutral	1,94	deleterious	-3,75	deleterious	-5,7	high_impact	3,73	damaging	0,53	damaging	0,07	deleterious	4,11	23,7	0,05	0,35	neutral	0,38	disease	0,9	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,77	low_impact	-3,78	medium_impact	0,14	high_impact	2,16	0,21	0,8	73,18	11,71	N	0,44	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9520	9520	G	C	MI.7306	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	314	105	S	T	aGc/aCc	8,69	1	0	probably_damaging	0,96	neutral	0,43	neutral	2	neutral	-2,31	deleterious	-2,85	high_impact	4,28	damaging	0,54	damaging	0,07	deleterious	3,4	23	0,17	0,45	neutral	0,22	disease	0,71	disease	0,6	disease	0,64	3	neutral	0,96	neutral	0,24	deleterious	2	deleterious	0,68	low_impact	-2,21	medium_impact	0,12	high_impact	2,65	0,32	0,8	73,18	11,71	N	0,5	N	0,63	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9520	9520	G	A	MI.7307	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	314	105	S	N	aGc/aAc	8,69	1	0	probably_damaging	0,96	neutral	0,32	neutral	1,95	deleterious	-3,24	deleterious	-2,86	high_impact	4,28	damaging	0,46	damaging	0,06	deleterious	3,58	23,2	0,36	0,5	neutral	0,23	disease	0,82	disease	0,61	disease	0,67	3	neutral	0,96	neutral	0,18	deleterious	2	deleterious	0,7	low_impact	-2,21	medium_impact	0,01	high_impact	2,65	0,23	0,8	73,18	11,71	P	0,55	P	0,88	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9522	9522	C	A	MI.7308	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	316	106	L	M	Cta/Ata	-0,1	0	0	probably_damaging	0,99	neutral	0,22	neutral	1,63	deleterious	-3,12	neutral	-1,75	medium_impact	2,73	damaging	0,58	damaging	0,04	deleterious	3,69	23,3	0,26	0,45	neutral	0,29	neutral	0,45	neutral	0,44	neutral	0,4	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,67	low_impact	-2,81	medium_impact	-0,12	medium_impact	1,26	0,5	0,8	73,95	11,57	N	0,33	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9522	9522	C	G	MI.7309	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	316	106	L	V	Cta/Gta	-0,1	0	0	probably_damaging	0,91	neutral	0,51	neutral	1,67	neutral	-2,72	deleterious	-2,52	medium_impact	2,43	damaging	0,5	damaging	0,06	deleterious	3,37	22,9	0,22	0,45	neutral	0,21	disease	0,6	neutral	0,49	neutral	0,43	1	neutral	0,9	neutral	0,3	deleterious	1	deleterious	0,52	low_impact	-1,85	medium_impact	0,2	medium_impact	1	0,41	0,8	73,95	11,57	N	0,25	N	0,81	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8871	8871	A	T	MI.731	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	345	115	M	I	atA/atT	-1,03	0	0	benign	0,01	neutral	0,78	neutral	4,44	neutral	0,76	neutral	0,34	neutral_impact	-1,41	neutral	0,88	neutral	0,96	neutral	-1,04	0,01	0,61	0,7	neutral	0,34	neutral	0,23	neutral	0,34	neutral	0,41	2	neutral	0,2	deleterious	0,89	neutral	-6	neutral	0,15	medium_impact	1,14	medium_impact	0,6	low_impact	-2,31	0,46	0,9	21,24	12,41	N	0,28	N	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9523	9523	T	A	MI.7310	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	317	106	L	Q	cTa/cAa	-0,1	0	0	probably_damaging	0,99	neutral	0,29	neutral	1,53	deleterious	-5,82	deleterious	-5,41	high_impact	3,64	damaging	0,6	damaging	0,02	deleterious	4,06	23,7	0,04	0,35	neutral	0,42	disease	0,81	disease	0,62	disease	0,66	3	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,76	low_impact	-2,81	medium_impact	-0,03	high_impact	2,08	0,08	0,8	73,95	11,57	N	0,26	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9523	9523	T	G	MI.7311	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	317	106	L	R	cTa/cGa	-0,1	0	0	probably_damaging	0,99	neutral	0,35	neutral	1,53	deleterious	-5,84	deleterious	-5,46	high_impact	4,09	neutral	0,67	damaging	0,02	deleterious	4,16	23,8	0,03	0,35	neutral	0,42	disease	0,88	disease	0,69	disease	0,72	4	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,82	low_impact	-2,81	medium_impact	0,04	high_impact	2,48	0,07	0,8	73,95	11,57	N	0,29	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9523	9523	T	C	MI.7312	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	317	106	L	P	cTa/cCa	-0,1	0	0	probably_damaging	1	neutral	0,22	neutral	1,53	deleterious	-6,51	deleterious	-6,34	high_impact	3,75	damaging	0,53	damaging	0,04	deleterious	3,89	23,5	0,03	0,35	disease	0,56	disease	0,8	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	-0,12	high_impact	2,18	0,1	0,8	73,95	11,57	N	0,27	N	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9525	9525	G	T	MI.7313	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	319	107	A	S	Gcc/Tcc	-2,42	0	0	probably_damaging	0,98	neutral	0,82	neutral	2,33	neutral	0,04	neutral	-0,46	neutral_impact	-0,02	neutral	0,64	neutral	0,73	deleterious	0,57	7,92	0,21	0,45	neutral	0,11	neutral	0,12	neutral	0,13	neutral	0,25	5	deleterious	0,98	neutral	0,42	neutral	-2	deleterious	0,61	low_impact	-2,51	medium_impact	0,57	low_impact	-1,2	0,31	0,8	33,72	16,42	N	0,36	N	0,33	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9525	9525	G	C	MI.7314	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	319	107	A	P	Gcc/Ccc	-2,42	0	0	probably_damaging	1	neutral	0,34	neutral	2,1	deleterious	-3,15	deleterious	-3,28	medium_impact	3,23	damaging	0,54	neutral	0,36	deleterious	3,69	23,3	0,06	0,35	neutral	0,42	disease	0,83	neutral	0,48	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,78	low_impact	-3,78	medium_impact	0,03	medium_impact	1,71	0,28	0,8	33,72	16,42	N	0,35	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9525	9525	G	A	MI.7315	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	319	107	A	T	Gcc/Acc	-2,42	0	0	probably_damaging	0,99	neutral	0,59	neutral	2,17	neutral	-1,37	neutral	-1,85	low_impact	1,44	neutral	0,64	neutral	0,66	deleterious	2,24	17,78	0,19	0,45	neutral	0,17	disease	0,56	neutral	0,22	neutral	0,42	2	deleterious	0,98	neutral	0,3	neutral	-2	deleterious	0,66	low_impact	-2,81	medium_impact	0,28	medium_impact	0,11	0,48	0,8	33,72	16,42	N	0,33	N	0,41	polymorphism	1	0,03	rs878977410	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9526	9526	C	T	MI.7316	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	320	107	A	V	gCc/gTc	5,22	1	0	probably_damaging	0,98	neutral	0,33	neutral	2,2	neutral	-1,01	deleterious	-2,8	low_impact	0,98	neutral	0,64	neutral	0,71	neutral	1,66	14,18	0,13	0,4	neutral	0,16	disease	0,54	neutral	0,25	neutral	0,43	1	deleterious	0,98	neutral	0,18	neutral	-2	deleterious	0,67	low_impact	-2,51	medium_impact	0,02	medium_impact	-0,3	0,54	0,8	33,72	16,42	P	0,51	P	0,11	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9526	9526	C	G	MI.7317	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	320	107	A	G	gCc/gGc	5,22	1	0	probably_damaging	0,95	neutral	0,39	neutral	2,12	neutral	-2,29	neutral	-2,39	low_impact	1,54	neutral	0,63	neutral	0,62	deleterious	2,27	17,98	0,22	0,45	neutral	0,33	neutral	0,5	neutral	0,37	neutral	0,46	1	neutral	0,95	neutral	0,22	neutral	-2	deleterious	0,66	low_impact	-2,11	medium_impact	0,08	medium_impact	0,2	0,56	0,8	33,72	16,42	N	0,5	N	0,6	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9526	9526	C	A	MI.7318	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	320	107	A	D	gCc/gAc	5,22	1	0	probably_damaging	1	neutral	0,63	neutral	2,11	neutral	-2,66	deleterious	-3,32	medium_impact	2,6	neutral	0,61	neutral	0,4	deleterious	4,43	24,2	0,05	0,35	neutral	0,28	disease	0,81	disease	0,59	disease	0,66	3	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,74	low_impact	-3,78	medium_impact	0,32	medium_impact	1,15	0,16	0,8	33,72	16,42	N	0,43	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9528	9528	C	G	MI.7319	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	322	108	P	A	Cct/Gct	-7,97	0	0	probably_damaging	0,99	neutral	1	neutral	1,05	deleterious	-4,98	deleterious	-7,54	medium_impact	2,48	neutral	0,64	damaging	0,04	deleterious	3,07	22,4	0,17	0,45	neutral	0,31	disease	0,55	disease	0,55	disease	0,53	1	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,72	low_impact	-2,81	high_impact	1,9	medium_impact	1,04	0,39	0,8	73,56	11,63	N	0,16	N	0,7	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8871	8871	A	C	MI.732	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	345	115	M	I	atA/atC	-1,03	0	0	benign	0,01	neutral	0,78	neutral	4,44	neutral	0,76	neutral	0,34	neutral_impact	-1,41	neutral	0,88	neutral	0,96	neutral	-1,15	0,01	0,61	0,7	neutral	0,34	neutral	0,23	neutral	0,34	neutral	0,41	2	neutral	0,2	deleterious	0,89	neutral	-6	neutral	0,15	medium_impact	1,14	medium_impact	0,6	low_impact	-2,31	0,46	0,9	21,24	12,41	N	0,28	N	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9528	9528	C	T	MI.7320	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	322	108	P	S	Cct/Tct	-7,97	0	0	probably_damaging	1	neutral	0,76	neutral	1,04	deleterious	-5,25	deleterious	-7,52	medium_impact	2,1	neutral	0,67	damaging	0,02	deleterious	3,89	23,5	0,21	0,45	neutral	0,32	disease	0,64	disease	0,54	neutral	0,43	2	deleterious	1	neutral	0,38	deleterious	1	deleterious	0,74	low_impact	-3,78	medium_impact	0,48	medium_impact	0,7	0,03	0,8	73,56	11,63	N	0,17	N	0,79	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9528	9528	C	A	MI.7321	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	322	108	P	T	Cct/Act	-7,97	0	0	probably_damaging	1	neutral	0,51	neutral	1,02	deleterious	-5,67	deleterious	-7,54	medium_impact	2,1	neutral	0,63	damaging	0,02	deleterious	3,72	23,3	0,17	0,45	neutral	0,22	disease	0,71	disease	0,54	disease	0,55	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,72	low_impact	-3,78	medium_impact	0,2	medium_impact	0,7	0,3	0,8	73,56	11,63	N	0,19	N	0,93	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9529	9529	C	T	MI.7322	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	323	108	P	L	cCt/cTt	7,3	1	0	probably_damaging	1	neutral	0,87	neutral	1,01	deleterious	-6	deleterious	-9,46	medium_impact	3,2	neutral	0,64	damaging	0,02	deleterious	4,27	24	0,13	0,4	neutral	0,44	disease	0,75	disease	0,62	disease	0,6	2	deleterious	1	neutral	0,44	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	0,66	medium_impact	1,69	0,57	0,8	73,56	11,63	N	0,36	N	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9529	9529	C	G	MI.7323	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	323	108	P	R	cCt/cGt	7,3	1	0	probably_damaging	1	neutral	0,31	neutral	1,01	deleterious	-6,18	deleterious	-8,5	high_impact	4,09	neutral	0,75	damaging	0,01	deleterious	3,57	23,1	0,08	0,35	neutral	0,4	disease	0,78	disease	0,72	disease	0,65	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,01	high_impact	2,48	0,17	0,8	73,56	11,63	N	0,47	N	0,93	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9529	9529	C	A	MI.7324	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	323	108	P	H	cCt/cAt	7,3	1	0	probably_damaging	1	neutral	0,47	neutral	0,99	deleterious	-7,29	deleterious	-8,5	medium_impact	3,06	neutral	0,62	damaging	0,02	deleterious	3,91	23,5	0,09	0,35	neutral	0,39	disease	0,76	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,76	low_impact	-3,78	medium_impact	0,16	medium_impact	1,56	0,15	0,8	73,56	11,63	N	0,36	N	0,88	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9531	9531	A	C	MI.7325	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	325	109	T	P	Acc/Ccc	-10,28	0	0	probably_damaging	0,99	neutral	0,25	neutral	2,16	neutral	-2,63	deleterious	-3,97	medium_impact	2,69	damaging	0,54	neutral	0,39	deleterious	4	23,6	0,1	0,4	neutral	0,37	disease	0,63	neutral	0,5	disease	0,51	0	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,7	low_impact	-2,81	medium_impact	-0,08	medium_impact	1,23	0,16	0,8	75,86	10,85	N	0,38	N	0,98	polymorphism	1	0,08	rs386829082	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9531	9531	A	T	MI.7326	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	325	109	T	S	Acc/Tcc	-10,28	0	0	probably_damaging	0,96	neutral	0,42	neutral	2,3	neutral	-0,19	neutral	-1,34	neutral_impact	0,45	neutral	0,65	neutral	0,72	deleterious	2,64	20,5	0,31	0,45	neutral	0,14	neutral	0,11	neutral	0,2	neutral	0,29	4	neutral	0,96	neutral	0,23	neutral	-2	deleterious	0,61	low_impact	-2,21	medium_impact	0,11	medium_impact	-0,78	0,33	0,8	75,86	10,85	N	0,41	N	0,77	polymorphism	1	0,03	rs386829082	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9531	9531	A	G	MI.7327	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	325	109	T	A	Acc/Gcc	-10,28	0	0	probably_damaging	0,96	neutral	0,52	neutral	2,32	neutral	-0,01	neutral	-2,37	low_impact	1,61	neutral	0,72	neutral	0,77	deleterious	2,9	21,8	0,22	0,45	neutral	0,1	neutral	0,17	neutral	0,25	neutral	0,28	4	neutral	0,95	neutral	0,28	neutral	-2	deleterious	0,6	low_impact	-2,21	medium_impact	0,21	medium_impact	0,26	0,2	0,8	75,86	10,85	N	0,36	N	0,44	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9532	9532	C	T	MI.7328	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	326	109	T	I	aCc/aTc	7,07	1	0	probably_damaging	1	neutral	0,42	neutral	2,18	neutral	-2,06	deleterious	-4,23	medium_impact	1,96	neutral	0,65	neutral	0,52	deleterious	3,94	23,5	0,12	0,4	neutral	0,35	neutral	0,5	disease	0,55	disease	0,58	2	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,69	low_impact	-3,78	medium_impact	0,11	medium_impact	0,57	0,22	0,8	75,86	10,85	N	0,45	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9532	9532	C	G	MI.7329	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	326	109	T	S	aCc/aGc	7,07	1	0	probably_damaging	0,96	neutral	0,42	neutral	2,3	neutral	-0,19	neutral	-1,34	neutral_impact	0,45	neutral	0,65	neutral	0,72	deleterious	2,29	18,11	0,31	0,45	neutral	0,14	neutral	0,11	neutral	0,2	neutral	0,29	4	neutral	0,96	neutral	0,23	neutral	-2	deleterious	0,61	low_impact	-2,21	medium_impact	0,11	medium_impact	-0,78	0,33	0,8	75,86	10,85	P	0,57	P	0,77	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8872	8872	G	C	MI.733	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	346	116	G	R	Ggc/Cgc	-3,34	0	0	possibly_damaging	0,87	neutral	0,06	neutral	3,85	deleterious	-3,96	deleterious	-7,44	high_impact	3,7	damaging	0,43	damaging	0,24	deleterious	3,75	23,3	0,17	0,65	disease	0,98	disease	0,94	disease	0,82	disease	0,75	5	neutral	0,97	neutral	0,1	deleterious	1	deleterious	0,9	low_impact	-1,54	medium_impact	-0,38	high_impact	2,07	0,88	0,9	49,56	8,7	P	0,53	P	0,98	disease_causing	0,95	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9532	9532	C	A	MI.7330	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	326	109	T	N	aCc/aAc	7,07	1	0	probably_damaging	0,99	neutral	0,31	neutral	2,22	neutral	-1,19	deleterious	-2,71	neutral_impact	0,72	neutral	0,67	neutral	0,72	deleterious	3,55	23,1	0,27	0,45	neutral	0,19	neutral	0,35	neutral	0,25	neutral	0,45	1	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,65	low_impact	-2,81	medium_impact	-0,01	medium_impact	-0,54	0,29	0,8	75,86	10,85	P	0,54	P	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9534	9534	C	G	MI.7331	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	328	110	P	A	Ccc/Gcc	-13,06	0	0	probably_damaging	0,98	neutral	0,77	neutral	2,4	neutral	-1,55	neutral	-1,88	low_impact	1,7	damaging	0,56	damaging	0,08	deleterious	1,97	16	0,25	0,45	neutral	0,13	neutral	0,18	neutral	0,32	neutral	0,31	4	deleterious	0,98	neutral	0,4	neutral	-2	deleterious	0,63	low_impact	-2,51	medium_impact	0,49	medium_impact	0,34	0,37	0,8	20,69	26,12	N	0,23	N	0,65	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9534	9534	C	A	MI.7332	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	328	110	P	T	Ccc/Acc	-13,06	0	0	probably_damaging	1	neutral	0,6	neutral	2,37	neutral	-1,94	neutral	-1,86	low_impact	1,47	damaging	0,55	damaging	0,05	deleterious	2,6	20,2	0,32	0,5	neutral	0,15	neutral	0,27	neutral	0,32	neutral	0,44	1	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,64	low_impact	-3,78	medium_impact	0,29	medium_impact	0,14	0,28	0,8	20,69	26,12	N	0,23	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9534	9534	C	T	MI.7333	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	328	110	P	S	Ccc/Tcc	-13,06	0	0	probably_damaging	1	neutral	0,63	neutral	2,36	neutral	-1,73	neutral	-2,41	low_impact	1,88	damaging	0,54	damaging	0,05	deleterious	3,81	23,4	0,29	0,45	neutral	0,15	neutral	0,26	neutral	0,3	neutral	0,43	1	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,64	low_impact	-3,78	medium_impact	0,32	medium_impact	0,5	0,11	0,8	20,69	26,12	N	0,21	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9535	9535	C	T	MI.7334	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	329	110	P	L	cCc/cTc	4,52	0,97	0	probably_damaging	1	neutral	0,8	neutral	2,45	neutral	-2,33	neutral	-1,61	medium_impact	2	damaging	0,57	damaging	0,08	deleterious	3,25	22,8	0,2	0,45	neutral	0,13	neutral	0,35	neutral	0,33	neutral	0,44	1	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,64	low_impact	-3,78	medium_impact	0,54	medium_impact	0,61	0,24	0,8	20,69	26,12	N	0,36	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9535	9535	C	G	MI.7335	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	329	110	P	R	cCc/cGc	4,52	0,97	0	probably_damaging	1	neutral	0,51	neutral	2,33	neutral	-2,09	deleterious	-3,17	medium_impact	3,42	damaging	0,5	damaging	0,04	deleterious	3,56	23,1	0,14	0,4	neutral	0,19	neutral	0,48	neutral	0,46	neutral	0,49	0	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,68	low_impact	-3,78	medium_impact	0,2	medium_impact	1,88	0,29	0,8	20,69	26,12	N	0,44	N	0,86	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9535	9535	C	A	MI.7336	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	329	110	P	H	cCc/cAc	4,52	0,97	0	probably_damaging	1	neutral	0,63	neutral	2,33	neutral	-2,74	deleterious	-2,54	low_impact	1,32	damaging	0,56	damaging	0,09	deleterious	2,84	21,5	0,15	0,45	neutral	0,15	neutral	0,35	neutral	0,28	neutral	0,45	1	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,65	low_impact	-3,78	medium_impact	0,32	medium_impact	0	0,18	0,8	20,69	26,12	N	0,36	N	0,22	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9537	9537	C	A	MI.7337	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	331	111	Q	K	Caa/Aaa	-13,29	0	0	benign	0,01	neutral	0,91	neutral	2,34	neutral	0,35	neutral	-1,1	neutral_impact	0,7	damaging	0,57	damaging	0,24	deleterious	2,05	16,52	0,31	0,5	neutral	0,09	neutral	0,32	disease	0,56	neutral	0,43	2	neutral	0,05	deleterious	0,95	neutral	-6	neutral	0,15	medium_impact	1,07	medium_impact	0,76	medium_impact	-0,56	0,11	0,8	23,37	58,38	N	0,28	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9537	9537	C	G	MI.7338	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	331	111	Q	E	Caa/Gaa	-13,29	0	0	benign	0,02	neutral	1	neutral	2,79	neutral	3,06	neutral	2,16	neutral_impact	-3,04	neutral	0,76	neutral	0,94	neutral	-1,53	0	0,38	0,5	neutral	0,12	neutral	0,04	neutral	0,19	neutral	0,23	5	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,1	medium_impact	0,77	high_impact	1,9	low_impact	-3,91	0,12	0,8	23,37	58,38	N	0,39	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9538	9538	A	C	MI.7339	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	332	111	Q	P	cAa/cCa	3,6	1	0	benign	0,08	neutral	0,28	neutral	2,27	neutral	-1,39	deleterious	-2,63	neutral_impact	0	damaging	0,48	damaging	0,14	neutral	1,33	12,45	0,12	0,4	neutral	0,26	disease	0,62	disease	0,51	disease	0,52	0	neutral	0,69	deleterious	0,6	neutral	-6	neutral	0,27	medium_impact	0,16	medium_impact	-0,04	low_impact	-1,18	0,12	0,8	23,37	58,38	N	0,49	N	0,67	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8872	8872	G	A	MI.734	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	346	116	G	S	Ggc/Agc	-3,34	0	0	benign	0,1	neutral	0,1	neutral	3,97	deleterious	-3,5	deleterious	-5,54	medium_impact	2,5	damaging	0,44	neutral	0,37	deleterious	2,24	17,79	0,27	0,65	disease	0,81	disease	0,86	disease	0,66	disease	0,51	0	neutral	0,89	deleterious	0,5	neutral	-3	neutral	0,38	medium_impact	0,15	medium_impact	-0,25	medium_impact	1,05	0,77	0,9	49,56	8,7	N	0,45	N	0,98	disease_causing	0,9	0,18	rs28410452	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9538	9538	A	T	MI.7340	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	332	111	Q	L	cAa/cTa	3,6	1	0	benign	0,02	neutral	0,34	neutral	2,28	neutral	-1,09	deleterious	-4,55	neutral_impact	0,2	neutral	0,62	damaging	0,24	deleterious	1,89	15,55	0,14	0,4	neutral	0,19	neutral	0,35	neutral	0,49	neutral	0,4	2	neutral	0,65	deleterious	0,66	neutral	-6	neutral	0,16	medium_impact	0,77	medium_impact	0,03	low_impact	-1	0,04	0,8	23,37	58,38	N	0,47	N	0,57	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9538	9538	A	G	MI.7341	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	332	111	Q	R	cAa/cGa	3,6	1	0	benign	0	neutral	0,53	neutral	2,3	neutral	-0,45	neutral	-1,94	neutral_impact	-0,04	damaging	0,53	damaging	0,22	neutral	1,5	13,3	0,3	0,45	neutral	0,13	neutral	0,42	disease	0,59	neutral	0,41	2	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,17	high_impact	2,05	medium_impact	0,22	low_impact	-1,22	0,04	0,8	23,37	58,38	N	0,48	N	0,42	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9539	9539	A	T	MI.7342	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	333	111	Q	H	caA/caT	7,07	1	0	benign	0	neutral	0,17	neutral	2,28	neutral	-1,25	neutral	-1,96	neutral_impact	0,7	neutral	0,63	neutral	0,42	neutral	1,8	14,98	0,33	0,5	neutral	0,23	neutral	0,24	neutral	0,43	neutral	0,38	2	neutral	0,83	deleterious	0,59	neutral	-6	neutral	0,15	high_impact	2,05	medium_impact	-0,2	medium_impact	-0,56	0,09	0,8	23,37	58,38	P	0,66	P	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9539	9539	A	C	MI.7343	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	333	111	Q	H	caA/caC	7,07	1	0	benign	0	neutral	0,17	neutral	2,28	neutral	-1,25	neutral	-1,96	neutral_impact	0,7	neutral	0,63	neutral	0,42	neutral	1,5	13,29	0,33	0,5	neutral	0,23	neutral	0,24	neutral	0,43	neutral	0,38	2	neutral	0,83	deleterious	0,59	neutral	-6	neutral	0,15	high_impact	2,05	medium_impact	-0,2	medium_impact	-0,56	0,09	0,8	23,37	58,38	P	0,66	P	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9540	9540	T	G	MI.7344	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	334	112	L	V	Tta/Gta	0,82	0,13	0,71	probably_damaging	0,95	neutral	0,59	neutral	2,04	neutral	-1,26	neutral	-1,38	low_impact	1,64	neutral	0,64	damaging	0,19	neutral	1,68	14,31	0,34	0,5	neutral	0,18	neutral	0,27	neutral	0,32	neutral	0,43	1	neutral	0,94	neutral	0,32	neutral	-2	deleterious	0,62	low_impact	-2,11	medium_impact	0,28	medium_impact	0,29	0,22	0,8	18,77	32,97	N	0,27	N	0,81	polymorphism	1	0,02	rs2248727	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9540	9540	T	A	MI.7345	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	334	112	L	M	Tta/Ata	0,82	0,13	0,71	probably_damaging	1	neutral	0,25	neutral	1,86	deleterious	-3,25	neutral	-1,48	medium_impact	2,9	damaging	0,6	damaging	0,04	deleterious	3,68	23,3	0,3	0,45	neutral	0,29	neutral	0,27	disease	0,52	neutral	0,47	1	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,67	low_impact	-3,78	medium_impact	-0,08	medium_impact	1,42	0,38	0,8	18,77	32,97	N	0,4	N	0,85	polymorphism	1	0,03	rs2248727	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9541	9541	T	G	MI.7346	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	335	112	L	W	tTa/tGa	-1,03	0	0	probably_damaging	1	neutral	0,2	neutral	1,81	deleterious	-6,38	deleterious	-5,19	high_impact	3,75	damaging	0,59	damaging	0,03	deleterious	3,76	23,3	0,08	0,35	disease	0,64	disease	0,52	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,75	low_impact	-3,78	medium_impact	-0,15	high_impact	2,18	0,18	0,8	18,77	32,97	N	0,32	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9541	9541	T	C	MI.7347	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	335	112	L	S	tTa/tCa	-1,03	0	0	probably_damaging	1	neutral	0,66	neutral	1,83	deleterious	-4,14	deleterious	-4,74	medium_impact	3	damaging	0,56	damaging	0,02	deleterious	3,63	23,2	0,04	0,35	neutral	0,32	disease	0,52	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	0,36	medium_impact	1,51	0,18	0,8	18,77	32,97	N	0,22	N	0,92	polymorphism	1	0,09	rs879143185	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9542	9542	A	T	MI.7348	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	336	112	L	F	ttA/ttT	7,53	0,99	0	probably_damaging	0,99	neutral	0,71	neutral	1,85	deleterious	-3,53	deleterious	-3,06	medium_impact	2,9	damaging	0,58	damaging	0,03	deleterious	3,51	23,1	0,28	0,45	neutral	0,28	neutral	0,44	disease	0,64	neutral	0,49	0	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,68	low_impact	-2,81	medium_impact	0,41	medium_impact	1,42	0,36	0,8	18,77	32,97	N	0,47	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9542	9542	A	C	MI.7349	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	336	112	L	F	ttA/ttC	7,53	0,99	0	probably_damaging	0,99	neutral	0,71	neutral	1,85	deleterious	-3,53	deleterious	-3,06	medium_impact	2,9	damaging	0,58	damaging	0,03	deleterious	3,43	23	0,28	0,45	neutral	0,28	neutral	0,44	disease	0,64	neutral	0,49	0	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,68	low_impact	-2,81	medium_impact	0,41	medium_impact	1,42	0,36	0,8	18,77	32,97	N	0,47	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8872	8872	G	T	MI.735	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	346	116	G	C	Ggc/Tgc	-3,34	0	0	probably_damaging	0,95	deleterious	0,03	neutral	3,84	deleterious	-6,43	deleterious	-8,35	medium_impact	3,23	damaging	0,47	damaging	0,23	deleterious	4,01	23,6	0,18	0,65	disease	0,97	disease	0,94	disease	0,74	disease	0,72	4	deleterious	0,99	neutral	0,04	deleterious	5	deleterious	0,91	low_impact	-1,97	medium_impact	-0,56	medium_impact	1,67	0,68	0,9	49,56	8,7	N	0,33	N	1	disease_causing	0,97	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9543	9543	G	T	MI.7350	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	337	113	G	W	Gga/Tga	-0,1	0,79	0	probably_damaging	1	neutral	0,19	neutral	1,63	deleterious	-7,62	deleterious	-7,61	high_impact	4,53	neutral	0,65	damaging	0,02	deleterious	4,46	24,2	0,09	0,35	neutral	0,3	disease	0,76	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,77	low_impact	-3,78	medium_impact	-0,17	high_impact	2,88	0,04	0,8	73,56	11,53	N	0,39	N	0,98	polymorphism	1	0,16	rs28635722	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9543	9543	G	C	MI.7351	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	337	113	G	R	Gga/Cga	-0,1	0,79	0	probably_damaging	1	neutral	0,35	neutral	1,67	deleterious	-4,38	deleterious	-7,6	high_impact	4,18	neutral	0,68	damaging	0,02	deleterious	3,95	23,6	0,07	0,35	neutral	0,22	disease	0,76	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	0,04	high_impact	2,56	0,36	0,8	73,56	11,53	N	0,41	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9544	9544	G	C	MI.7352	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	338	113	G	A	gGa/gCa	8,92	1	0	probably_damaging	1	neutral	0,52	neutral	1,74	neutral	-2,87	deleterious	-5,69	medium_impact	2,96	damaging	0,56	damaging	0	deleterious	3,12	22,6	0,17	0,45	neutral	0,13	disease	0,52	disease	0,59	disease	0,54	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,71	low_impact	-3,78	medium_impact	0,21	medium_impact	1,47	0,17	0,8	73,56	11,53	N	0,4	N	0,3	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9544	9544	G	T	MI.7353	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	338	113	G	V	gGa/gTa	8,92	1	0	probably_damaging	1	neutral	0,51	neutral	1,67	deleterious	-4,34	deleterious	-8,54	high_impact	3,98	damaging	0,54	damaging	0,01	deleterious	3,76	23,3	0,07	0,35	neutral	0,21	disease	0,76	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,74	low_impact	-3,78	medium_impact	0,2	high_impact	2,38	0,07	0,8	73,56	11,53	N	0,46	N	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9544	9544	G	A	MI.7354	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	338	113	G	E	gGa/gAa	8,92	1	0	probably_damaging	1	neutral	0,29	neutral	1,71	deleterious	-3,43	deleterious	-7,6	high_impact	3,73	damaging	0,58	damaging	0,01	deleterious	3,89	23,5	0,08	0,35	neutral	0,18	disease	0,75	disease	0,77	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,75	low_impact	-3,78	medium_impact	-0,03	high_impact	2,16	0,16	0,8	73,56	11,53	P	0,64	P	1	polymorphism	1	0,14	.	.	.	.	.	colonic crypts	.	.	.	G9544A	Sporadic bilateral optic neuropathy	.	.	Reported	1
chrM	9546	9546	G	C	MI.7355	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	340	114	G	R	Ggg/Cgg	-6,58	0	0	possibly_damaging	0,9	neutral	0,37	neutral	2,5	neutral	-1,81	neutral	-1,15	medium_impact	2,86	neutral	0,61	damaging	0,04	deleterious	2,87	21,7	0,1	0,4	neutral	0,19	disease	0,61	neutral	0,47	neutral	0,5	0	neutral	0,9	neutral	0,24	NA	0	deleterious	0,68	low_impact	-1,8	medium_impact	0,06	medium_impact	1,38	0,43	0,8	73,56	10,38	N	0,28	N	0,99	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9546	9546	G	T	MI.7356	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	340	114	G	W	Ggg/Tgg	-6,58	0	0	probably_damaging	0,93	neutral	0,32	neutral	2,46	deleterious	-4,73	neutral	-1,87	medium_impact	3,4	neutral	0,64	damaging	0,05	deleterious	4,5	24,3	0,11	0,4	disease	0,62	disease	0,6	neutral	0,47	neutral	0,48	0	neutral	0,94	neutral	0,2	deleterious	1	deleterious	0,73	low_impact	-1,96	medium_impact	0,01	medium_impact	1,86	0,1	0,8	73,56	10,38	N	0,28	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9547	9547	G	T	MI.7357	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	341	114	G	V	gGg/gTg	4,52	1	0	possibly_damaging	0,62	neutral	0,53	neutral	2,54	neutral	-2,4	neutral	0,03	medium_impact	2,08	neutral	0,71	damaging	0,15	deleterious	2,54	19,71	0,13	0,4	neutral	0,18	neutral	0,46	neutral	0,37	neutral	0,44	1	neutral	0,59	neutral	0,46	NA	0	deleterious	0,58	low_impact	-1,08	medium_impact	0,22	medium_impact	0,68	0,07	0,8	73,56	10,38	N	0,46	N	0,97	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9547	9547	G	A	MI.7358	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	341	114	G	E	gGg/gAg	4,52	1	0	possibly_damaging	0,9	neutral	0,35	neutral	2,52	neutral	-0,97	neutral	-1,14	low_impact	1,49	neutral	0,66	neutral	0,39	deleterious	2,4	18,82	0,11	0,4	neutral	0,11	disease	0,51	neutral	0,44	neutral	0,43	1	neutral	0,91	neutral	0,23	neutral	-3	deleterious	0,64	low_impact	-1,8	medium_impact	0,04	medium_impact	0,15	0,13	0,8	73,56	10,38	P	0,54	P	1	polymorphism	1	0,02	.	.	.	.	.	cloned platelet mtDNA	.	.	.	.	.	.	.	.	.
chrM	9547	9547	G	C	MI.7359	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	341	114	G	A	gGg/gCg	4,52	1	0	benign	0,1	neutral	0,58	neutral	2,62	neutral	-0,25	neutral	0,85	neutral_impact	0,68	neutral	0,68	neutral	0,76	neutral	1,27	12,13	0,24	0,45	neutral	0,08	neutral	0,13	neutral	0,16	neutral	0,26	5	neutral	0,33	deleterious	0,74	neutral	-6	neutral	0,25	medium_impact	0,06	medium_impact	0,27	medium_impact	-0,57	0,24	0,8	73,56	10,38	P	0,51	P	0,3	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8873	8873	G	T	MI.736	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	347	116	G	V	gGc/gTc	9,15	1	0	possibly_damaging	0,87	deleterious	0,01	neutral	3,89	deleterious	-3,82	deleterious	-8,35	medium_impact	3,36	damaging	0,44	neutral	0,28	deleterious	3,61	23,2	0,16	0,65	disease	0,95	disease	0,94	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,07	deleterious	4	deleterious	0,88	low_impact	-1,54	medium_impact	-0,84	medium_impact	1,78	0,63	0,9	49,56	8,7	P	0,62	P	0,99	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9549	9549	C	A	MI.7360	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	343	115	H	N	Cac/Aac	-11,67	0	0	probably_damaging	0,97	neutral	0,31	neutral	2,6	neutral	-0,16	neutral	0,43	neutral_impact	-0,97	neutral	0,76	neutral	0,85	deleterious	2,16	17,23	0,4	0,5	neutral	0,07	neutral	0,19	neutral	0,39	neutral	0,33	3	neutral	0,97	neutral	0,17	neutral	-2	deleterious	0,59	low_impact	-2,34	medium_impact	-0,01	low_impact	-2,05	0,28	0,8	22,61	51,84	N	0,38	N	0,52	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9549	9549	C	T	MI.7361	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	343	115	H	Y	Cac/Tac	-11,67	0	0	probably_damaging	0,97	neutral	1	neutral	2,61	neutral	-2,29	neutral	-0,31	neutral_impact	0,06	neutral	0,78	neutral	0,92	neutral	-0,17	1,27	0,36	0,5	neutral	0,14	neutral	0,17	neutral	0,43	neutral	0,28	4	neutral	0,97	deleterious	0,52	neutral	-2	deleterious	0,62	low_impact	-2,34	high_impact	1,9	low_impact	-1,13	0,18	0,8	22,61	51,84	N	0,23	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9549	9549	C	G	MI.7362	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	343	115	H	D	Cac/Gac	-11,67	0	0	probably_damaging	0,98	neutral	0,2	neutral	2,58	neutral	-0,54	neutral	-0,3	neutral_impact	-0,32	neutral	0,66	neutral	0,49	deleterious	2,31	18,25	0,11	0,4	neutral	0,1	neutral	0,25	disease	0,55	neutral	0,44	1	deleterious	0,99	neutral	0,11	neutral	-2	deleterious	0,62	low_impact	-2,51	medium_impact	-0,15	low_impact	-1,47	0,39	0,8	22,61	51,84	N	0,4	N	0,63	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9550	9550	A	T	MI.7363	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	344	115	H	L	cAc/cTc	1,98	0,09	0	probably_damaging	0,98	neutral	0,65	neutral	2,69	neutral	-0,92	neutral	0,1	neutral_impact	-0,73	neutral	0,76	neutral	0,77	deleterious	0,24	5,11	0,12	0,4	neutral	0,06	neutral	0,21	neutral	0,42	neutral	0,33	4	neutral	0,98	neutral	0,34	neutral	-2	deleterious	0,61	low_impact	-2,51	medium_impact	0,35	low_impact	-1,84	0,09	0,8	22,61	51,84	N	0,34	N	0,54	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9550	9550	A	C	MI.7364	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	344	115	H	P	cAc/cCc	1,98	0,09	0	probably_damaging	0,99	neutral	0,22	neutral	2,59	neutral	-1,07	neutral	-0,75	neutral_impact	-0,64	damaging	0,6	neutral	0,36	deleterious	1,96	15,96	0,12	0,4	neutral	0,16	disease	0,53	neutral	0,5	neutral	0,46	1	deleterious	0,99	neutral	0,12	neutral	-2	deleterious	0,68	low_impact	-2,81	medium_impact	-0,12	low_impact	-1,76	0,19	0,8	22,61	51,84	N	0,38	N	0,82	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9550	9550	A	G	MI.7365	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	344	115	H	R	cAc/cGc	1,98	0,09	0	probably_damaging	0,98	neutral	0,34	neutral	2,6	neutral	-0,59	neutral	-0,1	neutral_impact	0,34	neutral	0,73	neutral	0,56	neutral	1,37	12,64	0,22	0,45	neutral	0,08	neutral	0,23	neutral	0,45	neutral	0,39	2	deleterious	0,98	neutral	0,18	neutral	-2	deleterious	0,63	low_impact	-2,51	medium_impact	0,03	medium_impact	-0,88	0,16	0,8	22,61	51,84	N	0,47	N	0,49	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9551	9551	C	G	MI.7366	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	345	115	H	Q	caC/caG	0,36	0,02	0	probably_damaging	0,99	neutral	0,29	neutral	2,61	neutral	0,12	neutral	0,75	neutral_impact	-1,51	neutral	0,77	neutral	0,84	neutral	1,71	14,47	0,32	0,5	neutral	0,07	neutral	0,08	neutral	0,32	neutral	0,25	5	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,6	low_impact	-2,81	medium_impact	-0,03	low_impact	-2,54	0,25	0,8	22,61	51,84	N	0,42	N	0,5	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9551	9551	C	A	MI.7367	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	345	115	H	Q	caC/caA	0,36	0,02	0	probably_damaging	0,99	neutral	0,29	neutral	2,61	neutral	0,12	neutral	0,75	neutral_impact	-1,51	neutral	0,77	neutral	0,84	deleterious	1,98	16,1	0,32	0,5	neutral	0,07	neutral	0,08	neutral	0,32	neutral	0,25	5	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,6	low_impact	-2,81	medium_impact	-0,03	low_impact	-2,54	0,25	0,8	22,61	51,84	N	0,42	N	0,5	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9552	9552	T	C	MI.7368	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	346	116	W	R	Tgg/Cgg	-0,8	0	0	probably_damaging	1	neutral	0,53	neutral	1,08	deleterious	-6,27	deleterious	-13,29	high_impact	3,94	neutral	0,67	damaging	0,03	deleterious	3,62	23,2	0,07	0,35	disease	0,58	disease	0,86	disease	0,84	disease	0,75	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	0,22	high_impact	2,35	0,07	0,8	73,18	11,82	N	0,36	N	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9552	9552	T	G	MI.7369	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	346	116	W	G	Tgg/Ggg	-0,8	0	0	probably_damaging	0,99	neutral	0,41	neutral	1,08	deleterious	-6,23	deleterious	-12,34	high_impact	3,94	neutral	0,61	damaging	0,02	deleterious	3,91	23,5	0,07	0,35	disease	0,65	disease	0,71	disease	0,83	disease	0,72	4	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,76	low_impact	-2,81	medium_impact	0,1	high_impact	2,35	0,1	0,8	73,18	11,82	N	0,34	N	0,98	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8873	8873	G	C	MI.737	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	347	116	G	A	gGc/gCc	9,15	1	0	benign	0,31	neutral	0,06	neutral	3,91	deleterious	-3,25	deleterious	-5,5	medium_impact	2,86	damaging	0,57	neutral	0,36	neutral	1,32	12,38	0,34	0,65	disease	0,74	disease	0,82	disease	0,7	disease	0,64	3	neutral	0,93	neutral	0,38	neutral	-3	deleterious	0,63	medium_impact	-0,43	medium_impact	-0,38	medium_impact	1,35	0,81	0,9	49,56	8,7	P	0,52	P	0,79	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9553	9553	G	C	MI.7370	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	347	116	W	S	tGg/tCg	7,53	1	0	probably_damaging	1	neutral	0,74	neutral	1,08	deleterious	-6,14	deleterious	-13,28	high_impact	4,39	neutral	0,65	damaging	0,02	deleterious	4,03	23,7	0,1	0,4	disease	0,54	disease	0,87	disease	0,81	disease	0,74	5	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	0,45	high_impact	2,75	0,11	0,8	73,18	11,82	N	0,47	N	0,97	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9553	9553	G	T	MI.7371	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	347	116	W	L	tGg/tTg	7,53	1	0	probably_damaging	0,99	neutral	0,33	neutral	1,12	deleterious	-4,94	deleterious	-12,34	high_impact	3,64	damaging	0,6	damaging	0,02	deleterious	4,24	23,9	0,12	0,4	neutral	0,21	disease	0,76	disease	0,82	disease	0,71	4	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,73	low_impact	-2,81	medium_impact	0,02	high_impact	2,08	0,13	0,8	73,18	11,82	N	0,47	N	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9554	9554	G	T	MI.7372	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	348	116	W	C	tgG/tgT	7,53	1	0,02	probably_damaging	1	neutral	0,07	neutral	1,06	deleterious	-7,73	deleterious	-12,35	high_impact	4,39	neutral	0,66	damaging	0,02	deleterious	4,17	23,8	0,07	0,35	disease	0,77	disease	0,86	disease	0,84	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	-0,45	high_impact	2,75	0,1	0,8	73,18	11,82	N	0,47	N	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9554	9554	G	C	MI.7373	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	348	116	W	C	tgG/tgC	7,53	1	0,02	probably_damaging	1	neutral	0,07	neutral	1,06	deleterious	-7,73	deleterious	-12,35	high_impact	4,39	neutral	0,66	damaging	0,02	deleterious	4	23,6	0,07	0,35	disease	0,77	disease	0,86	disease	0,84	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	-0,45	high_impact	2,75	0,1	0,8	73,18	11,82	N	0,47	N	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9555	9555	C	T	MI.7374	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	349	117	P	S	Ccc/Tcc	2,67	1	0	probably_damaging	1	neutral	0,42	neutral	1,95	neutral	-1,85	deleterious	-7,58	medium_impact	3,48	neutral	0,65	damaging	0,01	deleterious	3,93	23,5	0,36	0,5	neutral	0,18	disease	0,6	disease	0,65	disease	0,54	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,72	low_impact	-3,78	medium_impact	0,11	medium_impact	1,94	0,03	0,8	73,56	11,79	N	0,37	N	0,79	polymorphism	1	0,2	rs28754412	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9555	9555	C	G	MI.7375	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	349	117	P	A	Ccc/Gcc	2,67	1	0	probably_damaging	0,99	neutral	0,51	neutral	1,92	neutral	-2,23	deleterious	-7,58	medium_impact	3,48	neutral	0,64	damaging	0,03	deleterious	3,04	22,4	0,3	0,45	neutral	0,19	neutral	0,49	disease	0,71	disease	0,58	2	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,69	low_impact	-2,81	medium_impact	0,2	medium_impact	1,94	0,33	0,8	73,56	11,79	N	0,37	N	0,7	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9555	9555	C	A	MI.7376	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	349	117	P	T	Ccc/Acc	2,67	1	0	probably_damaging	1	neutral	0,41	neutral	1,87	neutral	-2,95	deleterious	-7,58	high_impact	3,53	neutral	0,64	damaging	0,01	deleterious	3,67	23,2	0,33	0,5	neutral	0,24	disease	0,7	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,72	low_impact	-3,78	medium_impact	0,1	medium_impact	1,98	0,34	0,8	73,56	11,79	N	0,31	N	0,93	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9556	9556	C	G	MI.7377	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	350	117	P	R	cCc/cGc	4,52	1	0	probably_damaging	1	neutral	0,36	neutral	1,83	deleterious	-3,78	deleterious	-8,54	high_impact	4,13	neutral	0,76	damaging	0,01	deleterious	3,56	23,1	0,17	0,45	neutral	0,3	disease	0,73	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,77	low_impact	-3,78	medium_impact	0,05	high_impact	2,52	0,21	0,8	73,56	11,79	N	0,46	N	0,93	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9556	9556	C	T	MI.7378	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	350	117	P	L	cCc/cTc	4,52	1	0	probably_damaging	1	neutral	0,67	neutral	1,83	deleterious	-3,84	deleterious	-9,49	medium_impact	3	neutral	0,63	damaging	0,01	deleterious	4,42	24,2	0,18	0,45	neutral	0,23	disease	0,64	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,72	low_impact	-3,78	medium_impact	0,37	medium_impact	1,51	0,44	0,8	73,56	11,79	N	0,35	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9556	9556	C	A	MI.7379	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	350	117	P	H	cCc/cAc	4,52	1	0	probably_damaging	1	neutral	0,54	neutral	1,81	deleterious	-4,9	deleterious	-8,54	high_impact	3,98	neutral	0,62	damaging	0,01	deleterious	3,97	23,6	0,19	0,45	neutral	0,44	disease	0,71	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	0,23	high_impact	2,38	0,17	0,8	73,56	11,79	N	0,46	N	0,88	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8873	8873	G	A	MI.738	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	347	116	G	D	gGc/gAc	9,15	1	0	possibly_damaging	0,68	deleterious	0	neutral	3,85	deleterious	-4,5	deleterious	-6,53	high_impact	4,51	damaging	0,54	damaging	0,27	deleterious	3,61	23,2	0,19	0,65	disease	0,97	disease	0,94	disease	0,81	disease	0,69	4	deleterious	1	neutral	0,16	deleterious	5	deleterious	0,85	low_impact	-1,07	low_impact	-1,4	high_impact	2,77	0,5	0,9	49,56	8,7	P	0,55	P	1	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9558	9558	C	A	MI.7380	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	352	118	P	T	Cca/Aca	-20	0	0	probably_damaging	1	neutral	0,49	neutral	1,02	deleterious	-5,67	deleterious	-7,68	high_impact	3,6	damaging	0,59	neutral	0,37	deleterious	3,72	23,3	0,35	0,5	disease	0,54	disease	0,73	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	0,18	high_impact	2,04	0,46	0,8	73,56	11,66	N	0,27	N	0,93	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9558	9558	C	G	MI.7381	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	352	118	P	A	Cca/Gca	-20	0	0	probably_damaging	0,99	neutral	0,49	neutral	1,05	deleterious	-4,98	deleterious	-7,68	medium_impact	3,31	damaging	0,58	neutral	0,49	deleterious	3,08	22,5	0,35	0,5	neutral	0,45	disease	0,52	disease	0,72	disease	0,59	2	deleterious	0,99	neutral	0,25	deleterious	1	deleterious	0,75	low_impact	-2,81	medium_impact	0,18	medium_impact	1,78	0,53	0,8	73,56	11,66	N	0,34	N	0,7	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9558	9558	C	T	MI.7382	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	352	118	P	S	Cca/Tca	-20	0	0	probably_damaging	1	neutral	0,53	neutral	1,04	deleterious	-5,25	deleterious	-7,68	medium_impact	3,1	neutral	0,65	neutral	0,44	deleterious	3,92	23,5	0,36	0,5	neutral	0,46	disease	0,64	disease	0,69	disease	0,55	1	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	0,22	medium_impact	1,6	0,1	0,8	73,56	11,66	N	0,3	N	0,79	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9559	9559	C	G	MI.7383	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	353	118	P	R	cCa/cGa	7,3	1	0	probably_damaging	1	neutral	0,33	neutral	1,01	deleterious	-6,18	deleterious	-8,64	high_impact	4,34	damaging	0,53	neutral	0,33	deleterious	3,57	23,2	0,16	0,45	disease	0,62	disease	0,78	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	0,02	high_impact	2,71	0,17	0,8	73,56	11,66	P	0,56	P	0,93	polymorphism	1	0,26	rs2856984	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9559	9559	C	T	MI.7384	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	353	118	P	L	cCa/cTa	7,3	1	0	probably_damaging	1	neutral	0,68	neutral	1,01	deleterious	-6	deleterious	-9,61	high_impact	3,54	damaging	0,54	neutral	0,45	deleterious	4,36	24,1	0,26	0,45	disease	0,65	disease	0,69	disease	0,7	disease	0,57	1	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	0,38	medium_impact	1,99	0,45	0,8	73,56	11,66	P	0,52	P	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9559	9559	C	A	MI.7385	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	353	118	P	Q	cCa/cAa	7,3	1	0	probably_damaging	1	neutral	0,28	neutral	1,01	deleterious	-6,42	deleterious	-7,69	high_impact	3,6	neutral	0,61	neutral	0,41	deleterious	4,05	23,7	0,24	0,45	disease	0,57	disease	0,75	disease	0,75	disease	0,6	2	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	-0,04	high_impact	2,04	0,19	0,8	73,56	11,66	N	0,52	P	0,86	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9561	9561	A	C	MI.7386	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	355	119	T	P	Aca/Cca	-7,51	0	0	probably_damaging	0,99	neutral	0,26	neutral	2,62	neutral	-1,41	deleterious	-2,64	low_impact	1,45	damaging	0,59	damaging	0,06	deleterious	3,5	23,1	0,16	0,45	neutral	0,36	neutral	0,48	neutral	0,24	neutral	0,41	2	deleterious	0,99	neutral	0,14	neutral	-2	deleterious	0,69	low_impact	-2,81	medium_impact	-0,07	medium_impact	0,12	0,17	0,8	48,66	11,95	N	0,3	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9561	9561	A	T	MI.7387	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	355	119	T	S	Aca/Tca	-7,51	0	0	probably_damaging	0,92	neutral	0,4	neutral	2,55	neutral	-0,09	neutral	-0,72	low_impact	1	neutral	0,68	neutral	0,42	deleterious	2,23	17,69	0,42	0,55	neutral	0,16	neutral	0,12	neutral	0,15	neutral	0,3	4	neutral	0,92	neutral	0,24	neutral	-2	deleterious	0,59	low_impact	-1,9	medium_impact	0,09	medium_impact	-0,29	0,15	0,8	48,66	11,95	N	0,45	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9561	9561	A	G	MI.7388	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	355	119	T	A	Aca/Gca	-7,51	0	0	probably_damaging	0,92	neutral	0,51	neutral	2,58	neutral	0,41	neutral	-1,45	neutral_impact	0,44	neutral	0,71	neutral	0,55	deleterious	2,16	17,23	0,32	0,5	neutral	0,13	neutral	0,09	neutral	0,25	neutral	0,29	4	neutral	0,91	neutral	0,3	neutral	-2	deleterious	0,57	low_impact	-1,9	medium_impact	0,2	medium_impact	-0,79	0,18	0,8	48,66	11,95	N	0,28	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9562	9562	C	A	MI.7389	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	356	119	T	K	aCa/aAa	0,82	0	0	probably_damaging	0,98	neutral	0,3	neutral	2,58	neutral	0,3	neutral	-1,01	neutral_impact	0,54	neutral	0,65	damaging	0,21	deleterious	3,15	22,6	0,14	0,4	neutral	0,14	neutral	0,16	neutral	0,17	neutral	0,27	5	deleterious	0,98	neutral	0,16	neutral	-2	deleterious	0,63	low_impact	-2,51	medium_impact	-0,02	medium_impact	-0,7	0,24	0,8	48,66	11,95	N	0,47	N	0,92	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8875	8875	T	C	MI.739	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	349	117	F	L	Ttt/Ctt	-20	0	0	benign	0	neutral	0,97	neutral	4,5	neutral	-0,84	neutral	-1,16	neutral_impact	-0,11	neutral	0,95	neutral	0,89	neutral	-0,53	0,19	0,39	0,65	neutral	0,4	neutral	0,3	neutral	0,27	neutral	0,47	1	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,12	high_impact	2,09	medium_impact	1,14	low_impact	-1,19	0,76	0,9	22,57	16,62	N	0,28	N	0,07	polymorphism	1	0,02	rs201123510	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9562	9562	C	T	MI.7390	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	356	119	T	M	aCa/aTa	0,82	0	0	probably_damaging	1	neutral	0,25	neutral	2,53	neutral	-2,15	neutral	-1,83	low_impact	1,33	neutral	0,68	neutral	0,35	deleterious	2,81	21,4	0,23	0,45	neutral	0,25	neutral	0,12	neutral	0,17	neutral	0,31	4	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,62	low_impact	-3,78	medium_impact	-0,08	medium_impact	0,01	0,18	0,8	48,66	11,95	N	0,5	N	0,95	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9564	9564	G	T	MI.7391	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	358	120	G	C	Ggc/Tgc	-2,65	0	0	probably_damaging	1	neutral	0,18	neutral	1,64	deleterious	-5,82	deleterious	-8,23	high_impact	4,21	neutral	0,6	damaging	0,02	deleterious	4,14	23,8	0,09	0,35	disease	0,78	disease	0,89	disease	0,63	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	-0,18	high_impact	2,59	0,03	0,8	73,95	11,76	N	0,33	N	0,98	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9564	9564	G	A	MI.7392	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	358	120	G	S	Ggc/Agc	-2,65	0	0	probably_damaging	1	neutral	0,55	neutral	1,73	deleterious	-3,08	deleterious	-5,28	medium_impact	3,01	damaging	0,48	damaging	0,05	deleterious	4,13	23,8	0,18	0,45	neutral	0,43	disease	0,74	neutral	0,5	neutral	0,43	1	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,79	low_impact	-3,78	medium_impact	0,24	medium_impact	1,52	0,43	0,8	73,95	11,76	N	0,27	N	0,85	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9564	9564	G	C	MI.7393	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	358	120	G	R	Ggc/Cgc	-2,65	0	0	probably_damaging	1	neutral	0,45	neutral	1,67	deleterious	-4,38	deleterious	-7,24	high_impact	4,21	damaging	0,6	damaging	0,02	deleterious	3,95	23,6	0,11	0,4	disease	0,54	disease	0,87	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	0,14	high_impact	2,59	0,54	0,8	73,95	11,76	N	0,31	N	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9565	9565	G	T	MI.7394	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	359	120	G	V	gGc/gTc	7,3	1	0	probably_damaging	1	neutral	0,57	neutral	1,67	deleterious	-4,34	deleterious	-8,23	high_impact	4	damaging	0,57	damaging	0,01	deleterious	3,78	23,4	0,1	0,4	disease	0,53	disease	0,87	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	0,26	high_impact	2,4	0,05	0,8	73,95	11,76	N	0,45	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9565	9565	G	C	MI.7395	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	359	120	G	A	gGc/gCc	7,3	1	0	probably_damaging	0,99	neutral	0,65	neutral	1,74	neutral	-2,87	deleterious	-5,43	medium_impact	2,89	neutral	0,64	damaging	0,03	deleterious	3,13	22,6	0,23	0,45	neutral	0,4	disease	0,73	neutral	0,49	neutral	0,47	1	deleterious	0,98	neutral	0,33	deleterious	1	deleterious	0,8	low_impact	-2,81	medium_impact	0,35	medium_impact	1,41	0,16	0,8	73,95	11,76	N	0,36	N	0,3	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9565	9565	G	A	MI.7396	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	359	120	G	D	gGc/gAc	7,3	1	0	probably_damaging	1	neutral	0,32	neutral	1,7	deleterious	-3,59	deleterious	-6,02	medium_impact	3,4	damaging	0,56	damaging	0,02	deleterious	3,84	23,4	0,12	0,4	disease	0,53	disease	0,85	neutral	0,5	disease	0,6	2	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,83	low_impact	-3,78	medium_impact	0,01	medium_impact	1,86	0,06	0,8	73,95	11,76	N	0,4	N	0,98	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9567	9567	A	G	MI.7397	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	361	121	I	V	Atc/Gtc	-9,82	0	0	possibly_damaging	0,87	neutral	0,35	neutral	1,98	neutral	-1,37	neutral	-0,67	low_impact	1,56	neutral	0,68	neutral	0,81	deleterious	1,92	15,74	0,54	0,6	neutral	0,17	neutral	0,2	neutral	0,34	neutral	0,32	4	neutral	0,88	neutral	0,24	neutral	-3	deleterious	0,46	low_impact	-1,67	medium_impact	0,04	medium_impact	0,22	0,2	0,8	76,63	10,68	N	0,46	N	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9567	9567	A	T	MI.7398	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	361	121	I	F	Atc/Ttc	-9,82	0	0	probably_damaging	0,99	neutral	0,15	neutral	1,76	deleterious	-3,93	deleterious	-3,83	high_impact	3,62	damaging	0,6	damaging	0,05	deleterious	3,85	23,4	0,17	0,45	neutral	0,38	disease	0,66	disease	0,68	disease	0,56	1	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,74	low_impact	-2,81	medium_impact	-0,24	high_impact	2,06	0,28	0,8	76,63	10,68	N	0,26	N	0,94	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9567	9567	A	C	MI.7399	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	361	121	I	L	Atc/Ctc	-9,82	0	0	probably_damaging	0,95	neutral	0,43	neutral	1,96	neutral	-1,48	neutral	-1,88	medium_impact	2,56	neutral	0,66	damaging	0,13	deleterious	3,82	23,4	0,27	0,45	neutral	0,2	neutral	0,48	neutral	0,49	neutral	0,37	3	neutral	0,95	neutral	0,24	deleterious	1	deleterious	0,51	low_impact	-2,11	medium_impact	0,12	medium_impact	1,11	0,37	0,8	76,63	10,68	N	0,29	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8558	8558	C	G	MI.74	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	32	11	A	G	gCc/gGc	1,05	0,01	0	benign	0,19	neutral	0,11	neutral	4,62	neutral	-1,42	neutral	-1,8	neutral_impact	0	neutral	0,82	neutral	0,56	deleterious	3,33	22,9	0,36	0,65	disease	0,51	disease	0,58	neutral	0,44	neutral	0,48	0	neutral	0,87	neutral	0,46	neutral	-6	neutral	0,39	medium_impact	-0,16	medium_impact	-0,22	low_impact	-1,1	0,58	0,9	23,45	19,76	N	0,39	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8875	8875	T	A	MI.740	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	349	117	F	I	Ttt/Att	-20	0	0	benign	0,07	neutral	0,74	neutral	4,54	neutral	-0,12	neutral	-1,96	low_impact	1,39	neutral	0,85	neutral	0,57	deleterious	2,5	19,49	0,26	0,65	neutral	0,43	disease	0,69	neutral	0,36	neutral	0,5	0	neutral	0,17	deleterious	0,84	neutral	-6	neutral	0,24	medium_impact	0,31	medium_impact	0,55	medium_impact	0,09	0,6	0,9	22,57	16,62	N	0,24	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9568	9568	T	C	MI.7400	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	362	121	I	T	aTc/aCc	3,83	0,99	0	probably_damaging	1	neutral	0,62	neutral	1,76	deleterious	-3,99	deleterious	-4,48	medium_impact	2,5	neutral	0,65	damaging	0,05	deleterious	3,42	23	0,14	0,4	neutral	0,31	disease	0,73	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,75	low_impact	-3,78	medium_impact	0,31	medium_impact	1,06	0,17	0,8	76,63	10,68	N	0,33	N	0,91	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9568	9568	T	G	MI.7401	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	362	121	I	S	aTc/aGc	3,83	0,99	0	probably_damaging	1	neutral	0,78	neutral	1,74	deleterious	-4,63	deleterious	-5,59	medium_impact	3,23	neutral	0,68	damaging	0,05	deleterious	4,31	24	0,05	0,35	neutral	0,3	disease	0,79	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,39	deleterious	1	deleterious	0,76	low_impact	-3,78	medium_impact	0,51	medium_impact	1,71	0,1	0,8	76,63	10,68	N	0,33	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9568	9568	T	A	MI.7402	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	362	121	I	N	aTc/aAc	3,83	0,99	0	probably_damaging	1	neutral	0,55	neutral	1,72	deleterious	-5,62	deleterious	-6,57	high_impact	3,88	neutral	0,61	damaging	0,05	deleterious	4,45	24,2	0,11	0,4	disease	0,52	disease	0,8	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	0,24	high_impact	2,3	0,08	0,8	76,63	10,68	N	0,42	N	0,97	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9569	9569	C	A	MI.7403	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	363	121	I	M	atC/atA	7,53	1	0	probably_damaging	1	neutral	0,17	neutral	1,81	neutral	-2,9	deleterious	-2,71	medium_impact	3,04	neutral	0,66	damaging	0,05	deleterious	3,76	23,3	0,32	0,5	neutral	0,32	disease	0,52	disease	0,53	neutral	0,48	0	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,7	low_impact	-3,78	medium_impact	-0,2	medium_impact	1,54	0,32	0,8	76,63	10,68	N	0,49	N	0,66	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9569	9569	C	G	MI.7404	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	363	121	I	M	atC/atG	7,53	1	0	probably_damaging	1	neutral	0,17	neutral	1,81	neutral	-2,9	deleterious	-2,71	medium_impact	3,04	neutral	0,66	damaging	0,05	deleterious	3,31	22,9	0,32	0,5	neutral	0,32	disease	0,52	disease	0,53	neutral	0,48	0	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,7	low_impact	-3,78	medium_impact	-0,2	medium_impact	1,54	0,32	0,8	76,63	10,68	N	0,49	N	0,66	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9570	9570	A	T	MI.7405	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	364	122	T	S	Acc/Tcc	-3,34	0	0	benign	0,12	neutral	0,78	neutral	2,32	neutral	0	neutral	-0,53	low_impact	1,25	neutral	0,79	neutral	0,8	neutral	-0,22	0,99	0,62	0,65	neutral	0,11	neutral	0,1	neutral	0,14	neutral	0,31	4	neutral	0,11	deleterious	0,83	neutral	-6	neutral	0,12	medium_impact	-0,03	medium_impact	0,51	medium_impact	-0,06	0,59	0,8	22,61	31,69	N	0,4	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9570	9570	A	G	MI.7406	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	364	122	T	A	Acc/Gcc	-3,34	0	0	benign	0,06	neutral	0,79	neutral	2,34	neutral	0,19	neutral	-1,36	low_impact	1,5	neutral	0,73	neutral	0,39	deleterious	0,08	3,36	0,28	0,45	neutral	0,17	neutral	0,15	neutral	0,27	neutral	0,28	5	neutral	0,12	deleterious	0,87	neutral	-6	neutral	0,1	medium_impact	0,29	medium_impact	0,52	medium_impact	0,16	0,18	0,8	22,61	31,69	N	0,33	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9570	9570	A	C	MI.7407	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	364	122	T	P	Acc/Ccc	-3,34	0	0	possibly_damaging	0,55	neutral	0,37	neutral	2,24	neutral	-1,79	neutral	-2,25	low_impact	1,51	neutral	0,63	damaging	0,17	deleterious	2,08	16,7	0,1	0,4	neutral	0,37	neutral	0,47	neutral	0,3	disease	0,5	0	neutral	0,63	neutral	0,41	neutral	-3	deleterious	0,44	medium_impact	-0,95	medium_impact	0,06	medium_impact	0,17	0,31	0,8	22,61	31,69	N	0,3	N	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9571	9571	C	T	MI.7408	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	365	122	T	I	aCc/aTc	0,36	0	0	benign	0	neutral	0,34	neutral	2,26	neutral	-1,33	neutral	-1,66	low_impact	1,51	neutral	0,76	neutral	0,55	deleterious	0,26	5,28	0,27	0,45	neutral	0,2	neutral	0,15	neutral	0,23	neutral	0,29	4	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,09	high_impact	2,05	medium_impact	0,03	medium_impact	0,17	0,23	0,8	22,61	31,69	N	0,46	N	0,03	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9571	9571	C	A	MI.7409	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	365	122	T	N	aCc/aAc	0,36	0	0	benign	0,43	neutral	0,56	neutral	2,3	neutral	-0,32	neutral	-0,81	low_impact	0,95	neutral	0,77	neutral	0,95	deleterious	1,86	15,32	0,49	0,55	neutral	0,22	neutral	0,19	neutral	0,16	neutral	0,36	3	neutral	0,41	deleterious	0,57	neutral	-6	neutral	0,38	medium_impact	-0,75	medium_impact	0,25	medium_impact	-0,33	0,25	0,8	22,61	31,69	N	0,41	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8875	8875	T	G	MI.741	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	349	117	F	V	Ttt/Gtt	-20	0	0	benign	0,11	neutral	0,17	neutral	4,44	neutral	-1,15	deleterious	-2,75	low_impact	1,84	neutral	0,85	neutral	0,57	neutral	1,19	11,68	0,3	0,65	disease	0,67	disease	0,75	neutral	0,4	disease	0,56	1	neutral	0,81	deleterious	0,53	neutral	-6	neutral	0,29	medium_impact	0,11	medium_impact	-0,1	medium_impact	0,48	0,54	0,9	22,57	16,62	N	0,3	N	0,86	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9571	9571	C	G	MI.7410	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	365	122	T	S	aCc/aGc	0,36	0	0	benign	0,12	neutral	0,78	neutral	2,32	neutral	0	neutral	-0,53	low_impact	1,25	neutral	0,79	neutral	0,8	deleterious	0,02	2,78	0,62	0,65	neutral	0,11	neutral	0,1	neutral	0,14	neutral	0,31	4	neutral	0,11	deleterious	0,83	neutral	-6	neutral	0,12	medium_impact	-0,03	medium_impact	0,51	medium_impact	-0,06	0,59	0,8	22,61	31,69	N	0,37	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9573	9573	C	A	MI.7411	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	367	123	P	T	Ccg/Acg	-4,5	0	0	probably_damaging	0,99	neutral	0,4	neutral	2,54	neutral	-0,33	deleterious	-4,9	low_impact	1,14	neutral	0,66	neutral	0,28	deleterious	2,46	19,18	0,46	0,55	neutral	0,18	neutral	0,31	neutral	0,23	neutral	0,43	1	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,65	low_impact	-2,81	medium_impact	0,09	medium_impact	-0,16	0,49	0,8	73,18	11,49	N	0,33	N	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9573	9573	C	T	MI.7412	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	367	123	P	S	Ccg/Tcg	-4,5	0	0	probably_damaging	0,99	neutral	0,4	neutral	2,51	neutral	-0,41	deleterious	-5,35	medium_impact	2,1	damaging	0,53	damaging	0,08	deleterious	3,82	23,4	0,47	0,55	neutral	0,15	neutral	0,46	neutral	0,29	neutral	0,4	2	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,67	low_impact	-2,81	medium_impact	0,09	medium_impact	0,7	0,06	0,8	73,18	11,49	N	0,26	N	0,79	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9573	9573	C	G	MI.7413	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	367	123	P	A	Ccg/Gcg	-4,5	0	0	probably_damaging	0,94	neutral	0,51	neutral	2,58	neutral	-0,06	deleterious	-5,49	low_impact	1,12	neutral	0,65	neutral	0,29	deleterious	1,99	16,18	0,47	0,55	neutral	0,15	neutral	0,26	neutral	0,28	neutral	0,43	2	neutral	0,94	neutral	0,29	neutral	-2	deleterious	0,64	low_impact	-2,03	medium_impact	0,2	medium_impact	-0,18	0,46	0,8	73,18	11,49	N	0,28	N	0,7	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9574	9574	C	T	MI.7414	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	368	123	P	L	cCg/cTg	3,14	0,99	0	probably_damaging	1	neutral	0,66	neutral	2,56	neutral	-1,69	deleterious	-7,41	medium_impact	2,32	damaging	0,5	damaging	0,02	deleterious	4,36	24,1	0,25	0,45	neutral	0,2	disease	0,58	neutral	0,44	neutral	0,36	3	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,68	low_impact	-3,78	medium_impact	0,36	medium_impact	0,9	0,41	0,8	73,18	11,49	N	0,3	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9574	9574	C	G	MI.7415	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	368	123	P	R	cCg/cGg	3,14	0,99	0	probably_damaging	1	neutral	0,35	neutral	2,49	neutral	-1,02	deleterious	-6,65	high_impact	3,54	damaging	0,48	damaging	0,02	deleterious	3,61	23,2	0,2	0,45	neutral	0,21	disease	0,68	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,72	low_impact	-3,78	medium_impact	0,04	medium_impact	1,99	0,26	0,8	73,18	11,49	N	0,37	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9574	9574	C	A	MI.7416	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	368	123	P	Q	cCg/cAg	3,14	0,99	0	probably_damaging	1	neutral	0,3	neutral	2,5	neutral	-0,69	deleterious	-5,87	medium_impact	3,08	damaging	0,5	damaging	0,02	deleterious	4,09	23,7	0,23	0,45	neutral	0,2	disease	0,6	disease	0,59	disease	0,64	3	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,67	low_impact	-3,78	medium_impact	-0,02	medium_impact	1,58	0,22	0,8	73,18	11,49	N	0,36	N	0,86	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9576	9576	C	G	MI.7417	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	370	124	L	V	Cta/Gta	-12,83	0	0	probably_damaging	0,92	neutral	0,51	neutral	2,21	neutral	-0,62	neutral	-1,61	low_impact	1,68	damaging	0,49	damaging	0,01	deleterious	3,44	23	0,37	0,5	neutral	0,14	neutral	0,3	neutral	0,44	neutral	0,43	1	neutral	0,91	neutral	0,3	neutral	-2	deleterious	0,61	low_impact	-1,9	medium_impact	0,2	medium_impact	0,32	0,27	0,8	73,18	11,39	N	0,28	N	0,81	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9576	9576	C	A	MI.7418	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	370	124	L	M	Cta/Ata	-12,83	0	0	probably_damaging	1	neutral	0,23	neutral	2,04	neutral	-2,5	neutral	-0,78	low_impact	1,4	damaging	0,56	damaging	0,06	deleterious	3,74	23,3	0,29	0,45	neutral	0,26	neutral	0,29	neutral	0,26	neutral	0,44	1	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,68	low_impact	-3,78	medium_impact	-0,11	medium_impact	0,07	0,46	0,8	73,18	11,39	N	0,35	N	0,85	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9577	9577	T	C	MI.7419	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	371	124	L	P	cTa/cCa	-0,8	0	0	probably_damaging	1	neutral	0,25	neutral	2,02	deleterious	-3,14	deleterious	-5,22	medium_impact	2,56	damaging	0,48	damaging	0,02	deleterious	3,91	23,5	0,05	0,35	neutral	0,45	disease	0,77	disease	0,59	disease	0,62	2	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,81	low_impact	-3,78	medium_impact	-0,08	medium_impact	1,11	0,13	0,8	73,18	11,39	N	0,27	N	0,99	polymorphism	1	0,09	rs386829086	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8876	8876	T	C	MI.742	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	350	117	F	S	tTt/tCt	0,36	0,1	0	benign	0,34	neutral	0,18	neutral	4,26	neutral	-2,85	deleterious	-4,51	medium_impact	2,41	neutral	0,82	neutral	0,52	deleterious	3,74	23,3	0,22	0,65	disease	0,86	disease	0,73	disease	0,59	disease	0,74	5	neutral	0,79	neutral	0,42	neutral	-3	deleterious	0,54	medium_impact	-0,48	medium_impact	-0,08	medium_impact	0,97	0,63	0,9	22,57	16,62	N	0,35	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9577	9577	T	A	MI.7420	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	371	124	L	Q	cTa/cAa	-0,8	0	0	probably_damaging	1	neutral	0,32	neutral	2,01	deleterious	-3,58	deleterious	-4,29	high_impact	4,08	damaging	0,56	damaging	0,02	deleterious	4,06	23,7	0,07	0,35	neutral	0,25	disease	0,68	disease	0,6	disease	0,68	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,72	low_impact	-3,78	medium_impact	0,01	high_impact	2,47	0,11	0,8	73,18	11,39	N	0,32	N	0,97	polymorphism	1	0,12	rs386829086	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9577	9577	T	G	MI.7421	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	371	124	L	R	cTa/cGa	-0,8	0	0	probably_damaging	1	neutral	0,37	neutral	2,01	deleterious	-3,53	deleterious	-4,35	medium_impact	3,38	damaging	0,49	damaging	0,02	deleterious	4,18	23,8	0,04	0,35	neutral	0,31	disease	0,78	disease	0,68	disease	0,7	4	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,78	low_impact	-3,78	medium_impact	0,06	medium_impact	1,85	0,15	0,8	73,18	11,39	N	0,29	N	0,99	polymorphism	1	0,16	rs386829086	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9579	9579	A	T	MI.7422	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	373	125	N	Y	Aat/Tat	-7,28	0	0	possibly_damaging	0,72	neutral	1	neutral	2,01	deleterious	-4,34	deleterious	-7,24	medium_impact	3	neutral	0,64	neutral	0,38	deleterious	3,69	23,3	0,2	0,45	neutral	0,3	disease	0,67	disease	0,66	disease	0,66	3	neutral	0,72	deleterious	0,64	NA	0	deleterious	0,64	low_impact	-1,27	high_impact	1,9	medium_impact	1,51	0,12	0,8	77,78	9,98	N	0,22	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9579	9579	A	G	MI.7423	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	373	125	N	D	Aat/Gat	-7,28	0	0	benign	0	neutral	0,22	neutral	2,19	neutral	-0,79	deleterious	-3,7	low_impact	0,88	neutral	0,71	neutral	0,73	deleterious	0,1	3,56	0,53	0,6	neutral	0,13	neutral	0,14	neutral	0,36	neutral	0,26	5	neutral	0,78	deleterious	0,61	neutral	-6	neutral	0,11	high_impact	2,05	medium_impact	-0,12	medium_impact	-0,39	0,22	0,8	77,78	9,98	N	0,47	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9579	9579	A	C	MI.7424	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	373	125	N	H	Aat/Cat	-7,28	0	0	possibly_damaging	0,61	neutral	0,54	neutral	2,02	deleterious	-3,43	deleterious	-4,47	medium_impact	3	neutral	0,67	neutral	0,38	deleterious	3,05	22,4	0,4	0,5	neutral	0,32	disease	0,63	disease	0,6	disease	0,64	3	neutral	0,57	neutral	0,47	NA	0	deleterious	0,58	low_impact	-1,06	medium_impact	0,23	medium_impact	1,51	0,13	0,8	77,78	9,98	N	0,26	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9580	9580	A	T	MI.7425	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	374	125	N	I	aAt/aTt	1,29	0,73	0	possibly_damaging	0,63	neutral	0,39	neutral	2,01	deleterious	-4	deleterious	-8,09	high_impact	3,6	neutral	0,66	neutral	0,55	deleterious	3,73	23,3	0,16	0,45	neutral	0,35	disease	0,69	disease	0,61	disease	0,64	3	neutral	0,67	neutral	0,38	deleterious	1	deleterious	0,57	low_impact	-1,09	medium_impact	0,08	high_impact	2,04	0,09	0,8	77,78	9,98	N	0,4	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9580	9580	A	C	MI.7426	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	374	125	N	T	aAt/aCt	1,29	0,73	0	benign	0,12	neutral	0,39	neutral	2,05	neutral	-2,49	deleterious	-5,29	medium_impact	3,11	neutral	0,64	neutral	0,54	deleterious	2,94	22	0,35	0,5	neutral	0,19	disease	0,62	disease	0,61	disease	0,64	3	neutral	0,55	deleterious	0,64	neutral	-3	neutral	0,23	medium_impact	-0,03	medium_impact	0,08	medium_impact	1,61	0,18	0,8	77,78	9,98	N	0,4	N	0,87	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9580	9580	A	G	MI.7427	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	374	125	N	S	aAt/aGt	1,29	0,73	0	benign	0,02	neutral	0,4	neutral	2,1	neutral	-1,73	deleterious	-4,32	low_impact	1,53	neutral	0,67	neutral	0,61	neutral	1,15	11,46	0,52	0,6	neutral	0,14	neutral	0,47	neutral	0,4	neutral	0,33	3	neutral	0,59	deleterious	0,69	neutral	-6	neutral	0,15	medium_impact	0,77	medium_impact	0,09	medium_impact	0,19	0,17	0,8	77,78	9,98	N	0,37	N	0,94	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9581	9581	T	G	MI.7428	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	375	125	N	K	aaT/aaG	8,69	0,98	0	benign	0,14	neutral	0,3	neutral	2,09	neutral	-1,8	deleterious	-5,31	medium_impact	2,91	neutral	0,63	neutral	0,38	deleterious	3,74	23,3	0,39	0,5	neutral	0,13	disease	0,62	disease	0,64	disease	0,57	1	neutral	0,65	deleterious	0,58	neutral	-3	neutral	0,38	medium_impact	-0,1	medium_impact	-0,02	medium_impact	1,43	0,13	0,8	77,78	9,98	P	0,56	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9581	9581	T	A	MI.7429	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	375	125	N	K	aaT/aaA	8,69	0,98	0	benign	0,14	neutral	0,3	neutral	2,09	neutral	-1,8	deleterious	-5,31	medium_impact	2,91	neutral	0,63	neutral	0,38	deleterious	4,01	23,6	0,39	0,5	neutral	0,13	disease	0,62	disease	0,64	disease	0,57	1	neutral	0,65	deleterious	0,58	neutral	-3	neutral	0,38	medium_impact	-0,1	medium_impact	-0,02	medium_impact	1,43	0,13	0,8	77,78	9,98	P	0,57	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8876	8876	T	G	MI.743	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	350	117	F	C	tTt/tGt	0,36	0,1	0	possibly_damaging	0,81	neutral	0,05	neutral	4,28	deleterious	-3,97	deleterious	-4,19	medium_impact	2,49	neutral	0,78	neutral	0,45	deleterious	3,97	23,6	0,21	0,65	disease	0,93	disease	0,84	disease	0,61	disease	0,81	6	neutral	0,97	neutral	0,12	NA	0	deleterious	0,78	low_impact	-1,35	medium_impact	-0,43	medium_impact	1,04	0,37	0,9	22,57	16,62	N	0,31	N	0,81	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9582	9582	C	T	MI.7430	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	376	126	P	S	Ccc/Tcc	-1,03	0	0	probably_damaging	1	neutral	0,94	neutral	2,02	neutral	-2,01	deleterious	-7,08	medium_impact	3,15	neutral	0,67	damaging	0,03	deleterious	3,86	23,4	0,46	0,55	neutral	0,13	disease	0,66	disease	0,55	disease	0,61	2	deleterious	1	deleterious	0,47	deleterious	1	deleterious	0,71	low_impact	-3,78	medium_impact	0,87	medium_impact	1,64	0,07	0,8	73,95	11,66	N	0,18	N	0,79	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9582	9582	C	G	MI.7431	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	376	126	P	A	Ccc/Gcc	-1,03	0	0	probably_damaging	0,99	neutral	0,99	neutral	2,06	neutral	-1,52	deleterious	-6,91	medium_impact	2,46	damaging	0,53	damaging	0,11	deleterious	3,08	22,5	0,36	0,5	neutral	0,15	neutral	0,35	neutral	0,34	neutral	0,38	2	deleterious	0,99	deleterious	0,5	deleterious	1	deleterious	0,68	low_impact	-2,81	medium_impact	1,33	medium_impact	1,02	0,56	0,8	73,95	11,66	N	0,23	N	0,7	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9582	9582	C	A	MI.7432	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	376	126	P	T	Ccc/Acc	-1,03	0	0	probably_damaging	1	neutral	0,8	neutral	2,01	neutral	-2,08	deleterious	-7,14	medium_impact	3	damaging	0,51	damaging	0,04	deleterious	3,86	23,5	0,35	0,5	neutral	0,2	disease	0,63	neutral	0,47	neutral	0,23	5	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,71	low_impact	-3,78	medium_impact	0,54	medium_impact	1,51	0,51	0,8	73,95	11,66	N	0,21	N	0,93	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9583	9583	C	G	MI.7433	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	377	126	P	R	cCc/cGc	7,3	1	0	probably_damaging	1	neutral	0,68	neutral	1,95	deleterious	-3,3	deleterious	-8,12	high_impact	3,92	neutral	0,73	damaging	0,02	deleterious	3,64	23,2	0,17	0,45	neutral	0,21	disease	0,74	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,74	low_impact	-3,78	medium_impact	0,38	high_impact	2,33	0,24	0,8	73,95	11,66	N	0,43	N	0,93	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9583	9583	C	A	MI.7434	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	377	126	P	H	cCc/cAc	7,3	1	0	probably_damaging	1	neutral	0,59	neutral	1,92	deleterious	-4,43	deleterious	-8,18	medium_impact	3,5	neutral	0,61	damaging	0,01	deleterious	4,01	23,6	0,19	0,45	neutral	0,33	disease	0,73	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,75	low_impact	-3,78	medium_impact	0,28	medium_impact	1,95	0,19	0,8	73,95	11,66	N	0,37	N	0,88	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9583	9583	C	T	MI.7435	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	377	126	P	L	cCc/cTc	7,3	1	0	probably_damaging	1	neutral	0,9	neutral	1,96	neutral	-2,93	deleterious	-9,02	medium_impact	2,58	neutral	0,61	damaging	0,01	deleterious	4,41	24,1	0,26	0,45	neutral	0,19	disease	0,68	disease	0,56	disease	0,62	2	deleterious	1	neutral	0,45	deleterious	1	deleterious	0,7	low_impact	-3,78	medium_impact	0,74	medium_impact	1,13	0,41	0,8	73,95	11,66	N	0,36	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9585	9585	C	G	MI.7436	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	379	127	L	V	Cta/Gta	-5,89	0	0	benign	0,05	neutral	0,51	neutral	2,39	neutral	-0,93	neutral	-1,16	low_impact	1,72	neutral	0,61	damaging	0,08	neutral	1,71	14,49	0,34	0,5	neutral	0,15	neutral	0,27	disease	0,58	neutral	0,46	1	neutral	0,44	deleterious	0,73	neutral	-6	neutral	0,17	medium_impact	0,37	medium_impact	0,2	medium_impact	0,36	0,27	0,8	20,31	19,28	N	0,27	N	0,4	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9585	9585	C	A	MI.7437	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	379	127	L	M	Cta/Ata	-5,89	0	0	benign	0,05	neutral	0,22	neutral	2,33	neutral	-2,53	neutral	0,37	low_impact	1,05	neutral	0,72	neutral	0,83	deleterious	0,64	8,43	0,29	0,45	neutral	0,33	neutral	0,14	neutral	0,28	neutral	0,29	4	neutral	0,76	deleterious	0,59	neutral	-6	neutral	0,17	medium_impact	0,37	medium_impact	-0,12	medium_impact	-0,24	0,56	0,8	20,31	19,28	N	0,52	P	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9586	9586	T	G	MI.7438	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	380	127	L	R	cTa/cGa	-1,49	0	0	possibly_damaging	0,62	neutral	0,36	neutral	2,33	deleterious	-3,65	deleterious	-3,18	medium_impact	1,97	damaging	0,55	damaging	0,04	deleterious	4,15	23,8	0,03	0,35	neutral	0,27	disease	0,7	disease	0,63	disease	0,7	4	neutral	0,68	neutral	0,37	NA	0	deleterious	0,64	low_impact	-1,08	medium_impact	0,05	medium_impact	0,58	0,14	0,8	20,31	19,28	N	0,22	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9586	9586	T	A	MI.7439	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	380	127	L	Q	cTa/cAa	-1,49	0	0	possibly_damaging	0,62	neutral	0,3	neutral	2,31	deleterious	-3,55	deleterious	-2,94	medium_impact	2,47	neutral	0,62	damaging	0,06	deleterious	4,04	23,7	0,05	0,35	neutral	0,34	disease	0,53	disease	0,57	disease	0,68	4	neutral	0,73	neutral	0,34	NA	0	deleterious	0,63	low_impact	-1,08	medium_impact	-0,02	medium_impact	1,03	0,12	0,8	20,31	19,28	N	0,27	N	0,79	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8876	8876	T	A	MI.744	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	350	117	F	Y	tTt/tAt	0,36	0,1	0	benign	0,34	neutral	0,46	neutral	4,25	neutral	-2,92	neutral	-1,87	medium_impact	2,23	neutral	0,85	neutral	0,48	deleterious	2,49	19,43	0,29	0,65	disease	0,89	disease	0,67	disease	0,57	disease	0,71	4	neutral	0,46	deleterious	0,56	neutral	-3	deleterious	0,52	medium_impact	-0,48	medium_impact	0,25	medium_impact	0,81	0,68	0,9	22,57	16,62	N	0,29	N	0,75	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9586	9586	T	C	MI.7440	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	380	127	L	P	cTa/cCa	-1,49	0	0	possibly_damaging	0,88	neutral	0,22	neutral	2,36	deleterious	-4,07	deleterious	-4,12	low_impact	1,66	damaging	0,5	damaging	0,04	deleterious	3,9	23,5	0,04	0,35	neutral	0,49	disease	0,74	disease	0,56	disease	0,69	4	neutral	0,92	neutral	0,17	neutral	-3	deleterious	0,8	low_impact	-1,71	medium_impact	-0,12	medium_impact	0,31	0,13	0,8	20,31	19,28	N	0,26	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9588	9588	G	C	MI.7441	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	382	128	E	Q	Gaa/Caa	-1,26	0	0	probably_damaging	0,92	neutral	0,3	neutral	2,14	neutral	-1,43	neutral	0,2	low_impact	0,9	neutral	0,63	neutral	0,73	deleterious	1,81	15,05	0,31	0,45	neutral	0,2	neutral	0,13	neutral	0,29	neutral	0,23	5	neutral	0,94	neutral	0,19	neutral	-2	deleterious	0,65	low_impact	-1,9	medium_impact	-0,02	medium_impact	-0,38	0,43	0,8	73,56	11,27	N	0,51	P	0,87	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9588	9588	G	A	MI.7442	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	382	128	E	K	Gaa/Aaa	-1,26	0	0	probably_damaging	0,92	neutral	0,29	neutral	2,15	neutral	-1,33	neutral	-1,62	low_impact	1,25	neutral	0,72	neutral	0,56	deleterious	4,5	24,3	0,11	0,4	neutral	0,15	disease	0,57	neutral	0,5	neutral	0,39	2	neutral	0,94	neutral	0,19	neutral	-2	deleterious	0,69	low_impact	-1,9	medium_impact	-0,03	medium_impact	-0,06	0,71	0,85	73,56	11,27	N	0,34	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9589	9589	A	T	MI.7443	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	383	128	E	V	gAa/gTa	5,22	1	0	probably_damaging	0,96	neutral	0,5	neutral	2,06	neutral	-2,92	deleterious	-3,92	medium_impact	2,65	neutral	0,61	neutral	0,54	deleterious	4,09	23,7	0,09	0,35	neutral	0,38	disease	0,52	neutral	0,49	neutral	0,46	1	neutral	0,95	neutral	0,27	deleterious	1	deleterious	0,71	low_impact	-2,21	medium_impact	0,19	medium_impact	1,19	0,39	0,8	73,56	11,27	N	0,5	N	0,83	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9589	9589	A	G	MI.7444	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	383	128	E	G	gAa/gGa	5,22	1	0	probably_damaging	0,96	neutral	0,33	neutral	2,1	neutral	-2,08	deleterious	-3,39	neutral_impact	0,38	neutral	0,66	neutral	0,67	deleterious	3,13	22,6	0,15	0,4	neutral	0,32	neutral	0,25	neutral	0,42	neutral	0,44	1	neutral	0,97	neutral	0,19	neutral	-2	deleterious	0,68	low_impact	-2,21	medium_impact	0,02	medium_impact	-0,84	0,28	0,8	73,56	11,27	P	0,51	P	0,62	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9589	9589	A	C	MI.7445	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	383	128	E	A	gAa/gCa	5,22	1	0	probably_damaging	0,94	neutral	0,51	neutral	2,12	neutral	-1,72	deleterious	-2,66	low_impact	1,37	neutral	0,65	neutral	0,65	deleterious	3,53	23,1	0,17	0,45	neutral	0,2	neutral	0,3	neutral	0,45	neutral	0,44	1	neutral	0,94	neutral	0,29	neutral	-2	deleterious	0,67	low_impact	-2,03	medium_impact	0,2	medium_impact	0,05	0,29	0,8	73,56	11,27	P	0,53	P	0,66	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9590	9590	A	C	MI.7446	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	384	128	E	D	gaA/gaC	8,69	1	0	possibly_damaging	0,74	neutral	0,21	neutral	2,14	neutral	-1,41	neutral	-1,55	low_impact	0,8	neutral	0,63	neutral	0,68	deleterious	3,62	23,2	0,3	0,45	neutral	0,27	neutral	0,29	neutral	0,31	neutral	0,44	1	neutral	0,85	neutral	0,24	neutral	-3	deleterious	0,53	low_impact	-1,31	medium_impact	-0,14	medium_impact	-0,47	0,67	0,85	73,56	11,27	P	0,68	P	0,93	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9590	9590	A	T	MI.7447	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	384	128	E	D	gaA/gaT	8,69	1	0	possibly_damaging	0,74	neutral	0,21	neutral	2,14	neutral	-1,41	neutral	-1,55	low_impact	0,8	neutral	0,63	neutral	0,68	deleterious	3,76	23,3	0,3	0,45	neutral	0,27	neutral	0,29	neutral	0,31	neutral	0,44	1	neutral	0,85	neutral	0,24	neutral	-3	deleterious	0,53	low_impact	-1,31	medium_impact	-0,14	medium_impact	-0,47	0,67	0,85	73,56	11,27	P	0,69	P	0,93	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9591	9591	G	C	MI.7448	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	385	129	V	L	Gtc/Ctc	2,67	1	0	probably_damaging	0,93	neutral	0,87	neutral	2,16	neutral	-0,76	neutral	-2,08	low_impact	1,2	damaging	0,6	neutral	0,53	neutral	1,69	14,35	0,28	0,45	neutral	0,09	neutral	0,42	neutral	0,47	neutral	0,41	2	neutral	0,92	deleterious	0,47	neutral	-2	deleterious	0,58	low_impact	-1,96	medium_impact	0,66	medium_impact	-0,11	0,46	0,8	75,48	11,31	N	0,4	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9591	9591	G	T	MI.7449	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	385	129	V	F	Gtc/Ttc	2,67	1	0	probably_damaging	1	neutral	0,38	neutral	1,93	deleterious	-3,49	deleterious	-4,01	medium_impact	2,32	damaging	0,56	neutral	0,52	deleterious	3,71	23,3	0,07	0,35	neutral	0,35	disease	0,8	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,76	low_impact	-3,78	medium_impact	0,07	medium_impact	0,9	0,35	0,8	75,48	11,31	N	0,39	N	0,94	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8877	8877	T	A	MI.745	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	351	117	F	L	ttT/ttA	7,53	0,97	0,01	benign	0	neutral	0,97	neutral	4,5	neutral	-0,84	neutral	-1,16	neutral_impact	-0,11	neutral	0,95	neutral	0,89	neutral	-0,23	0,95	0,39	0,65	neutral	0,4	neutral	0,3	neutral	0,27	neutral	0,47	1	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,12	high_impact	2,09	medium_impact	1,14	low_impact	-1,19	0,76	0,9	22,57	16,62	N	0,49	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9591	9591	G	A	MI.7450	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	385	129	V	I	Gtc/Atc	2,67	1	0	probably_damaging	0,93	neutral	0,37	neutral	2,23	neutral	-0,39	neutral	-0,16	neutral_impact	0,73	neutral	0,65	neutral	0,76	deleterious	0,49	7,37	0,45	0,55	neutral	0,13	neutral	0,07	neutral	0,34	neutral	0,23	5	neutral	0,93	neutral	0,22	neutral	-2	deleterious	0,55	low_impact	-1,96	medium_impact	0,06	medium_impact	-0,53	0,64	0,8	75,48	11,31	P	0,56	P	0,21	polymorphism	1	0,01	rs878949273	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9592	9592	T	C	MI.7451	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	386	129	V	A	gTc/gCc	3,6	1	0	probably_damaging	0,99	neutral	0,92	neutral	1,96	neutral	-2,78	deleterious	-3,84	medium_impact	2,88	neutral	0,62	neutral	0,65	deleterious	3,47	23	0,18	0,45	neutral	0,28	disease	0,52	disease	0,64	disease	0,66	3	deleterious	0,99	neutral	0,47	deleterious	1	deleterious	0,72	low_impact	-2,81	medium_impact	0,8	medium_impact	1,4	0,11	0,8	75,48	11,31	N	0,42	N	0,39	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9592	9592	T	A	MI.7452	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	386	129	V	D	gTc/gAc	3,6	1	0	probably_damaging	1	neutral	0,64	neutral	1,9	deleterious	-5,2	deleterious	-6,34	medium_impact	3,23	damaging	0,57	neutral	0,5	deleterious	4,66	24,5	0,02	0,35	disease	0,67	disease	0,83	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,82	low_impact	-3,78	medium_impact	0,33	medium_impact	1,71	0,08	0,8	75,48	11,31	N	0,43	N	0,94	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9592	9592	T	G	MI.7453	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	386	129	V	G	gTc/gGc	3,6	1	0	probably_damaging	1	neutral	0,46	neutral	1,9	deleterious	-4,7	deleterious	-6,74	high_impact	3,92	damaging	0,59	neutral	0,6	deleterious	3,87	23,5	0,04	0,35	disease	0,54	disease	0,67	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,75	low_impact	-3,78	medium_impact	0,15	high_impact	2,33	0,23	0,8	75,48	11,31	N	0,47	N	0,88	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9594	9594	C	G	MI.7454	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	388	130	P	A	Cca/Gca	-20	0	0	probably_damaging	0,98	neutral	0,51	neutral	1,89	neutral	-2,33	deleterious	-7,67	medium_impact	2,42	neutral	0,62	damaging	0,03	deleterious	3,08	22,5	0,17	0,45	neutral	0,16	disease	0,6	disease	0,72	disease	0,67	3	deleterious	0,98	neutral	0,27	deleterious	1	deleterious	0,72	low_impact	-2,51	medium_impact	0,2	medium_impact	0,99	0,63	0,8	73,95	11,67	N	0,23	N	0,7	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9594	9594	C	T	MI.7455	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	388	130	P	S	Cca/Tca	-20	0	0	probably_damaging	1	neutral	0,4	neutral	1,92	neutral	-2,05	deleterious	-7,67	high_impact	3,54	neutral	0,68	damaging	0,01	deleterious	3,91	23,5	0,2	0,45	neutral	0,23	disease	0,78	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	0,09	medium_impact	1,99	0,15	0,8	73,95	11,67	N	0,27	N	0,79	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9594	9594	C	A	MI.7456	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	388	130	P	T	Cca/Aca	-20	0	0	probably_damaging	1	neutral	0,44	neutral	1,84	deleterious	-3,06	deleterious	-7,67	high_impact	3,79	neutral	0,63	damaging	0,01	deleterious	3,67	23,2	0,15	0,4	neutral	0,25	disease	0,75	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,75	low_impact	-3,78	medium_impact	0,13	high_impact	2,21	0,5	0,8	73,95	11,67	N	0,26	N	0,93	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9595	9595	C	A	MI.7457	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	389	130	P	Q	cCa/cAa	5,68	1	0	probably_damaging	1	neutral	0,33	neutral	1,8	deleterious	-3,93	deleterious	-7,68	high_impact	4,69	neutral	0,68	damaging	0,01	deleterious	4,07	23,7	0,11	0,4	neutral	0,27	disease	0,84	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	0,02	high_impact	3,02	0,32	0,8	73,95	11,67	P	0,58	P	0,86	polymorphism	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9595	9595	C	G	MI.7458	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	389	130	P	R	cCa/cGa	5,68	1	0	probably_damaging	1	neutral	0,35	neutral	1,8	deleterious	-3,87	deleterious	-8,64	high_impact	4,14	neutral	0,75	damaging	0,01	deleterious	3,59	23,2	0,05	0,35	neutral	0,28	disease	0,84	disease	0,83	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	0,04	high_impact	2,53	0,37	0,8	73,95	11,67	N	0,53	P	0,93	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9595	9595	C	T	MI.7459	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	389	130	P	L	cCa/cTa	5,68	1	0	probably_damaging	1	neutral	0,81	neutral	1,8	deleterious	-3,93	deleterious	-9,6	high_impact	4	damaging	0,59	damaging	0,02	deleterious	4,41	24,1	0,13	0,4	neutral	0,27	disease	0,83	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,41	deleterious	2	deleterious	0,75	low_impact	-3,78	medium_impact	0,55	high_impact	2,4	0,59	0,8	73,95	11,67	N	0,41	N	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8877	8877	T	G	MI.746	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	351	117	F	L	ttT/ttG	7,53	0,97	0,01	benign	0	neutral	0,97	neutral	4,5	neutral	-0,84	neutral	-1,16	neutral_impact	-0,11	neutral	0,95	neutral	0,89	neutral	-0,33	0,58	0,39	0,65	neutral	0,4	neutral	0,3	neutral	0,27	neutral	0,47	1	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,12	high_impact	2,09	medium_impact	1,14	low_impact	-1,19	0,76	0,9	22,57	16,62	N	0,49	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9597	9597	C	T	MI.7460	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	391	131	L	F	Ctc/Ttc	-15,37	0	0	probably_damaging	0,99	neutral	0,11	neutral	1,61	neutral	-2,99	deleterious	-3,85	medium_impact	2,53	damaging	0,46	damaging	0,03	deleterious	3,93	23,5	0,21	0,45	neutral	0,27	neutral	0,46	neutral	0,47	neutral	0,37	3	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,72	low_impact	-2,81	medium_impact	-0,33	medium_impact	1,09	0,56	0,8	73,95	11,81	N	0,33	N	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9597	9597	C	G	MI.7461	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	391	131	L	V	Ctc/Gtc	-15,37	0	0	probably_damaging	0,91	neutral	0,18	neutral	1,6	deleterious	-3,14	deleterious	-2,88	medium_impact	3,29	damaging	0,52	damaging	0,01	deleterious	3,46	23	0,3	0,45	neutral	0,26	neutral	0,47	disease	0,68	neutral	0,49	0	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,66	low_impact	-1,85	medium_impact	-0,18	medium_impact	1,77	0,56	0,8	73,95	11,81	N	0,3	N	0,81	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9597	9597	C	A	MI.7462	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	391	131	L	I	Ctc/Atc	-15,37	0	0	probably_damaging	0,96	neutral	0,24	neutral	1,62	neutral	-2,9	neutral	-1,92	medium_impact	3,14	damaging	0,57	damaging	0,02	deleterious	4,1	23,7	0,3	0,45	neutral	0,28	neutral	0,47	disease	0,58	neutral	0,44	1	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,68	low_impact	-2,21	medium_impact	-0,09	medium_impact	1,63	0,52	0,8	73,95	11,81	N	0,32	N	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9598	9598	T	G	MI.7463	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	392	131	L	R	cTc/cGc	0,13	0,02	0	probably_damaging	0,99	neutral	0,1	neutral	1,49	deleterious	-5,86	deleterious	-5,77	high_impact	4,26	neutral	0,67	damaging	0,02	deleterious	4,22	23,9	0,02	0,35	disease	0,52	disease	0,8	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,83	low_impact	-2,81	medium_impact	-0,35	high_impact	2,64	0,13	0,8	73,95	11,81	N	0,44	N	0,99	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9598	9598	T	C	MI.7464	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	392	131	L	P	cTc/cCc	0,13	0,02	0	probably_damaging	1	neutral	0,25	neutral	1,48	deleterious	-6,55	deleterious	-6,75	high_impact	4,26	damaging	0,53	damaging	0,03	deleterious	3,98	23,6	0,03	0,35	disease	0,63	disease	0,75	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,08	high_impact	2,64	0,26	0,8	73,95	11,81	N	0,36	N	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9598	9598	T	A	MI.7465	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	392	131	L	H	cTc/cAc	0,13	0,02	0	probably_damaging	1	neutral	0,09	neutral	1,48	deleterious	-6,33	deleterious	-6,74	high_impact	4,61	damaging	0,55	damaging	0,02	deleterious	4,33	24	0,05	0,35	disease	0,63	disease	0,77	disease	0,76	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,38	high_impact	2,95	0,2	0,8	73,95	11,81	N	0,44	N	0,97	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9600	9600	C	G	MI.7466	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	394	132	L	V	Cta/Gta	-6,81	0	0	probably_damaging	0,98	neutral	0,18	neutral	1,6	deleterious	-3,13	deleterious	-2,92	medium_impact	2,62	damaging	0,49	damaging	0,02	deleterious	3,43	23	0,32	0,5	neutral	0,21	neutral	0,5	disease	0,58	disease	0,55	1	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,69	low_impact	-2,51	medium_impact	-0,18	medium_impact	1,17	0,58	0,8	73,95	11,73	N	0,3	N	0,81	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9600	9600	C	A	MI.7467	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	394	132	L	M	Cta/Ata	-6,81	0	0	probably_damaging	1	neutral	0,08	neutral	1,55	deleterious	-3,87	neutral	-1,94	medium_impact	3,13	damaging	0,59	damaging	0,05	deleterious	3,76	23,3	0,27	0,45	neutral	0,43	neutral	0,5	disease	0,55	neutral	0,47	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	-0,41	medium_impact	1,62	0,55	0,8	73,95	11,73	N	0,29	N	0,85	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9601	9601	T	A	MI.7468	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	395	132	L	Q	cTa/cAa	-0,1	0	0	probably_damaging	1	neutral	0,13	neutral	1,49	deleterious	-5,84	deleterious	-5,84	high_impact	4,55	damaging	0,6	damaging	0,02	deleterious	4,11	23,7	0,02	0,35	disease	0,68	disease	0,8	disease	0,58	disease	0,65	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,28	high_impact	2,9	0,33	0,8	73,95	11,73	N	0,38	N	0,97	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9601	9601	T	C	MI.7469	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	395	132	L	P	cTa/cCa	-0,1	0	0	probably_damaging	1	neutral	0,2	neutral	1,49	deleterious	-6,54	deleterious	-6,82	medium_impact	3,13	damaging	0,56	damaging	0,03	deleterious	3,94	23,5	0,02	0,35	disease	0,73	disease	0,79	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,86	low_impact	-3,78	medium_impact	-0,15	medium_impact	1,62	0,26	0,8	73,95	11,73	N	0,26	N	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8878	8878	C	G	MI.747	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	352	118	R	G	Cgc/Ggc	-6,12	0	0	probably_damaging	0,99	neutral	0,33	neutral	4,33	neutral	-1,95	deleterious	-6,39	medium_impact	3,02	neutral	0,69	neutral	0,46	deleterious	4,17	23,8	0,23	0,65	disease	0,75	disease	0,88	disease	0,64	disease	0,71	4	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,84	low_impact	-2,65	medium_impact	0,12	medium_impact	1,49	0,46	0,9	47,35	8,78	N	0,27	N	1	polymorphism	0,98	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9601	9601	T	G	MI.7470	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	395	132	L	R	cTa/cGa	-0,1	0	0	probably_damaging	1	neutral	0,12	neutral	1,49	deleterious	-5,86	deleterious	-5,84	high_impact	4,21	neutral	0,67	damaging	0,02	deleterious	4,18	23,8	0,01	0,35	disease	0,66	disease	0,82	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,3	high_impact	2,59	0,2	0,8	73,95	11,73	N	0,38	N	0,99	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9603	9603	A	T	MI.7471	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	397	133	N	Y	Aac/Tac	-7,97	0	0	probably_damaging	1	neutral	1	neutral	1,83	deleterious	-5,06	deleterious	-7,79	high_impact	4,38	damaging	0,55	damaging	0,17	deleterious	3,74	23,3	0,07	0,35	neutral	0,47	disease	0,85	disease	0,74	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,8	low_impact	-3,78	high_impact	1,9	high_impact	2,74	0,21	0,8	73,95	11,62	N	0,34	N	1	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9603	9603	A	G	MI.7472	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	397	133	N	D	Aac/Gac	-7,97	0	0	probably_damaging	0,96	neutral	0,22	neutral	1,94	neutral	-2,14	deleterious	-4,87	high_impact	4,38	damaging	0,54	neutral	0,37	deleterious	3,86	23,5	0,25	0,45	neutral	0,4	disease	0,76	disease	0,79	disease	0,7	4	neutral	0,98	neutral	0,13	deleterious	2	deleterious	0,73	low_impact	-2,21	medium_impact	-0,12	high_impact	2,74	0,33	0,8	73,95	11,62	N	0,55	P	0,97	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9603	9603	A	C	MI.7473	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	397	133	N	H	Aac/Cac	-7,97	0	0	probably_damaging	1	neutral	0,54	neutral	1,84	deleterious	-4,29	deleterious	-4,87	high_impact	4,74	damaging	0,54	damaging	0,28	deleterious	3,11	22,5	0,2	0,45	neutral	0,49	disease	0,82	disease	0,8	disease	0,73	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	0,23	high_impact	3,07	0,28	0,8	73,95	11,62	P	0,65	P	0,96	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9604	9604	A	C	MI.7474	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	398	133	N	T	aAc/aCc	8,69	1	0,01	probably_damaging	0,98	neutral	0,65	neutral	1,87	deleterious	-3,37	deleterious	-5,84	high_impact	4,74	damaging	0,58	neutral	0,42	deleterious	3,41	23	0,16	0,45	neutral	0,29	disease	0,79	disease	0,73	disease	0,69	4	neutral	0,97	neutral	0,34	deleterious	2	deleterious	0,75	low_impact	-2,51	medium_impact	0,35	high_impact	3,07	0,3	0,8	73,95	11,62	P	0,64	P	0,87	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9604	9604	A	T	MI.7475	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	398	133	N	I	aAc/aTc	8,69	1	0,01	probably_damaging	1	neutral	0,46	neutral	1,83	deleterious	-4,65	deleterious	-8,77	medium_impact	3,38	damaging	0,56	neutral	0,48	deleterious	3,85	23,4	0,08	0,35	neutral	0,25	disease	0,87	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,75	low_impact	-3,78	medium_impact	0,15	medium_impact	1,85	0,19	0,8	73,95	11,62	N	0,51	P	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9604	9604	A	G	MI.7476	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	398	133	N	S	aAc/aGc	8,69	1	0,01	probably_damaging	0,91	neutral	0,62	neutral	1,89	neutral	-2,84	deleterious	-4,87	high_impact	3,84	damaging	0,5	neutral	0,41	deleterious	2,99	22,2	0,34	0,5	neutral	0,28	disease	0,79	disease	0,71	disease	0,69	4	neutral	0,89	neutral	0,36	deleterious	2	deleterious	0,73	low_impact	-1,85	medium_impact	0,31	high_impact	2,26	0,39	0,8	73,95	11,62	P	0,58	P	0,94	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9605	9605	C	G	MI.7477	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	399	133	N	K	aaC/aaG	8,69	1	0	probably_damaging	0,99	neutral	0,31	neutral	1,91	neutral	-2,6	deleterious	-5,84	high_impact	4,18	damaging	0,53	damaging	0,26	deleterious	3,99	23,6	0,18	0,45	neutral	0,28	disease	0,83	disease	0,79	disease	0,7	4	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,77	low_impact	-2,81	medium_impact	-0,01	high_impact	2,56	0,36	0,8	73,95	11,62	P	0,59	P	1	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9605	9605	C	A	MI.7478	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	399	133	N	K	aaC/aaA	8,69	1	0	probably_damaging	0,99	neutral	0,31	neutral	1,91	neutral	-2,6	deleterious	-5,84	high_impact	4,18	damaging	0,53	damaging	0,26	deleterious	4,41	24,1	0,18	0,45	neutral	0,28	disease	0,83	disease	0,79	disease	0,7	4	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,77	low_impact	-2,81	medium_impact	-0,01	high_impact	2,56	0,36	0,8	73,95	11,62	P	0,6	P	1	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9606	9606	A	C	MI.7479	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	400	134	T	P	Aca/Cca	-3,11	0	0	possibly_damaging	0,85	neutral	0,21	neutral	0,95	deleterious	-8,08	deleterious	-5,84	high_impact	4,78	neutral	0,64	damaging	0,06	deleterious	3,41	23	0,02	0,35	disease	0,71	disease	0,72	disease	0,83	disease	0,74	5	neutral	0,91	neutral	0,18	deleterious	1	deleterious	0,75	low_impact	-1,6	medium_impact	-0,14	high_impact	3,1	0,28	0,8	75,1	11,46	P	0,6	P	0,98	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8878	8878	C	A	MI.748	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	352	118	R	S	Cgc/Agc	-6,12	0	0	probably_damaging	0,99	neutral	0,4	neutral	4,42	neutral	-1,19	deleterious	-5,42	low_impact	1,48	neutral	0,7	neutral	0,48	deleterious	4,54	24,3	0,19	0,65	neutral	0,45	disease	0,89	disease	0,54	disease	0,63	3	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,82	low_impact	-2,65	medium_impact	0,19	medium_impact	0,17	0,39	0,9	47,35	8,78	N	0,26	N	0,77	polymorphism	0,98	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9606	9606	A	G	MI.7480	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	400	134	T	A	Aca/Gca	-3,11	0	0	benign	0,11	neutral	0,49	neutral	0,97	deleterious	-6,55	deleterious	-4,87	high_impact	4,22	neutral	0,65	damaging	0,04	deleterious	2,98	22,2	0,03	0,35	neutral	0,39	disease	0,54	disease	0,74	disease	0,69	4	neutral	0,43	deleterious	0,69	neutral	-2	neutral	0,26	medium_impact	0,01	medium_impact	0,18	high_impact	2,6	0,33	0,8	75,1	11,46	N	0,38	N	0,44	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9606	9606	A	T	MI.7481	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	400	134	T	S	Aca/Tca	-3,11	0	0	benign	0,24	neutral	0,34	neutral	1,14	deleterious	-3,81	deleterious	-3,9	medium_impact	3,09	neutral	0,66	damaging	0,07	deleterious	3,05	22,4	0,08	0,35	neutral	0,36	disease	0,6	disease	0,57	neutral	0,39	2	neutral	0,59	deleterious	0,55	neutral	-3	neutral	0,33	medium_impact	-0,38	medium_impact	0,03	medium_impact	1,59	0,48	0,8	75,1	11,46	N	0,31	N	0,77	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9607	9607	C	T	MI.7482	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	401	134	T	M	aCa/aTa	8,69	1	0	possibly_damaging	0,82	neutral	0,19	neutral	0,94	deleterious	-9,09	deleterious	-5,84	high_impact	4,78	neutral	0,69	damaging	0,01	deleterious	4,07	23,7	0,03	0,35	disease	0,73	disease	0,7	disease	0,76	disease	0,72	4	neutral	0,9	neutral	0,19	deleterious	1	deleterious	0,71	low_impact	-1,51	medium_impact	-0,17	high_impact	3,1	0,49	0,8	75,1	11,46	P	0,63	P	0,96	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9607	9607	C	A	MI.7483	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	401	134	T	K	aCa/aAa	8,69	1	0	possibly_damaging	0,6	neutral	0,24	neutral	0,95	deleterious	-7,92	deleterious	-5,84	high_impact	4,43	neutral	0,69	damaging	0,02	deleterious	4,49	24,3	0,03	0,35	disease	0,58	disease	0,78	disease	0,81	disease	0,73	5	neutral	0,77	neutral	0,32	deleterious	1	deleterious	0,65	low_impact	-1,04	medium_impact	-0,09	high_impact	2,79	0,43	0,8	75,1	11,46	P	0,58	P	0,99	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9609	9609	T	G	MI.7484	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	403	135	S	A	Tcc/Gcc	-2,88	0	0	benign	0	neutral	0,7	neutral	2,69	neutral	1,25	neutral	1,31	neutral_impact	-1,64	neutral	0,63	neutral	0,52	neutral	-0,87	0,03	0,21	0,45	neutral	0,11	neutral	0,04	neutral	0,25	neutral	0,18	6	neutral	0,29	deleterious	0,85	neutral	-6	neutral	0,11	high_impact	2,05	medium_impact	0,4	low_impact	-2,65	0,6	0,8	21,46	24,65	N	0,34	N	0,4	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9609	9609	T	C	MI.7485	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	403	135	S	P	Tcc/Ccc	-2,88	0	0	possibly_damaging	0,52	neutral	0,15	neutral	2,56	neutral	-2,09	neutral	-1,84	low_impact	0,94	damaging	0,44	damaging	0,09	deleterious	3,95	23,6	0,06	0,35	neutral	0,26	disease	0,63	disease	0,57	disease	0,64	3	neutral	0,84	neutral	0,32	neutral	-3	deleterious	0,45	medium_impact	-0,9	medium_impact	-0,24	medium_impact	-0,34	0,42	0,8	21,46	24,65	N	0,36	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9609	9609	T	A	MI.7486	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	403	135	S	T	Tcc/Acc	-2,88	0	0	benign	0,06	neutral	0,62	neutral	2,6	neutral	0,15	neutral	-0,23	neutral_impact	-0,43	neutral	0,62	damaging	0,23	neutral	0,97	10,49	0,21	0,45	neutral	0,16	neutral	0,11	neutral	0,28	neutral	0,3	4	neutral	0,31	deleterious	0,78	neutral	-6	neutral	0,13	medium_impact	0,29	medium_impact	0,31	low_impact	-1,57	0,64	0,8	21,46	24,65	N	0,28	N	0,63	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9610	9610	C	T	MI.7487	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	404	135	S	F	tCc/tTc	1,52	0,96	0	possibly_damaging	0,89	neutral	0,58	neutral	2,67	neutral	0,79	neutral	-1,89	neutral_impact	-0,04	damaging	0,45	damaging	0,14	deleterious	4,16	23,8	0,08	0,35	neutral	0,16	neutral	0,43	neutral	0,45	neutral	0,45	1	neutral	0,87	neutral	0,35	neutral	-3	deleterious	0,64	low_impact	-1,75	medium_impact	0,27	low_impact	-1,22	0,3	0,8	21,46	24,65	N	0,42	N	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9610	9610	C	A	MI.7488	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	404	135	S	Y	tCc/tAc	1,52	0,96	0	possibly_damaging	0,89	neutral	0,8	neutral	2,58	neutral	-0,87	neutral	-2,15	low_impact	1,56	damaging	0,47	damaging	0,12	deleterious	4,13	23,8	0,07	0,35	neutral	0,29	neutral	0,38	neutral	0,44	neutral	0,45	1	neutral	0,87	neutral	0,46	neutral	-3	deleterious	0,65	low_impact	-1,75	medium_impact	0,54	medium_impact	0,22	0,44	0,8	21,46	24,65	N	0,41	N	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9610	9610	C	G	MI.7489	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	404	135	S	C	tCc/tGc	1,52	0,96	0	possibly_damaging	0,82	neutral	0,13	neutral	2,54	neutral	-2,08	neutral	-0,96	low_impact	1,22	damaging	0,48	damaging	0,2	deleterious	3,51	23,1	0,06	0,35	neutral	0,41	neutral	0,38	neutral	0,43	neutral	0,47	1	neutral	0,93	neutral	0,16	neutral	-3	deleterious	0,6	low_impact	-1,51	medium_impact	-0,28	medium_impact	-0,09	0,39	0,8	21,46	24,65	P	0,51	P	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8878	8878	C	T	MI.749	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	352	118	R	C	Cgc/Tgc	-6,12	0	0	probably_damaging	1	neutral	0,18	neutral	4,31	deleterious	-4,83	deleterious	-7,1	medium_impact	2,82	neutral	0,7	neutral	0,29	deleterious	4,96	25	0,24	0,65	disease	0,93	disease	0,93	disease	0,65	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,89	low_impact	-3,6	medium_impact	-0,08	medium_impact	1,32	0,74	0,9	47,35	8,78	N	0,26	N	1	disease_causing	0,87	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9612	9612	G	A	MI.7490	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	406	136	V	M	Gta/Ata	-20	0	0,01	probably_damaging	1	neutral	0,07	neutral	2,04	neutral	-2,78	neutral	-2,35	high_impact	3,63	neutral	0,66	neutral	0,5	deleterious	3,75	23,3	0,16	0,45	disease	0,5	disease	0,63	disease	0,62	disease	0,69	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,74	low_impact	-3,78	medium_impact	-0,45	high_impact	2,07	0,8	0,85	67,82	10,97	N	0,39	N	0,81	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9612	9612	G	C	MI.7491	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	406	136	V	L	Gta/Cta	-20	0	0,01	probably_damaging	0,92	neutral	1	neutral	2,24	neutral	-0,44	neutral	-1,85	low_impact	1,23	neutral	0,69	neutral	0,48	deleterious	3,64	23,2	0,16	0,45	neutral	0,18	disease	0,57	neutral	0,39	neutral	0,33	4	neutral	0,92	deleterious	0,54	neutral	-2	deleterious	0,62	low_impact	-1,9	high_impact	1,9	medium_impact	-0,08	0,46	0,8	67,82	10,97	N	0,27	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9612	9612	G	T	MI.7492	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	406	136	V	L	Gta/Tta	-20	0	0,01	probably_damaging	0,92	neutral	1	neutral	2,24	neutral	-0,44	neutral	-1,85	low_impact	1,23	neutral	0,69	neutral	0,48	deleterious	3,75	23,3	0,16	0,45	neutral	0,18	disease	0,57	neutral	0,39	neutral	0,33	4	neutral	0,92	deleterious	0,54	neutral	-2	deleterious	0,62	low_impact	-1,9	high_impact	1,9	medium_impact	-0,08	0,46	0,8	67,82	10,97	N	0,27	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9613	9613	T	G	MI.7493	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	407	136	V	G	gTa/gGa	1,52	0,92	0	probably_damaging	1	neutral	0,12	neutral	2	deleterious	-4,68	deleterious	-6,65	high_impact	3,98	neutral	0,62	neutral	0,61	deleterious	3,88	23,5	0,03	0,35	disease	0,8	disease	0,76	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	-0,3	high_impact	2,38	0,3	0,8	67,82	10,97	N	0,43	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9613	9613	T	C	MI.7494	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	407	136	V	A	gTa/gCa	1,52	0,92	0	probably_damaging	0,99	neutral	0,37	neutral	2,04	neutral	-2,65	deleterious	-3,76	high_impact	3,63	neutral	0,62	neutral	0,63	deleterious	3,61	23,2	0,09	0,35	disease	0,5	disease	0,55	disease	0,59	disease	0,67	3	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,76	low_impact	-2,81	medium_impact	0,06	high_impact	2,07	0,28	0,8	67,82	10,97	N	0,42	N	0,84	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9613	9613	T	A	MI.7495	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	407	136	V	E	gTa/gAa	1,52	0,92	0	probably_damaging	0,99	neutral	0,07	neutral	2	deleterious	-4,44	deleterious	-5,68	high_impact	3,98	neutral	0,62	neutral	0,41	deleterious	4,68	24,5	0,03	0,35	disease	0,8	disease	0,89	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,88	low_impact	-2,81	medium_impact	-0,45	high_impact	2,38	0,24	0,8	67,82	10,97	N	0,46	N	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9615	9615	T	A	MI.7496	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	409	137	L	M	Tta/Ata	-10,28	0	0,01	probably_damaging	1	neutral	0,12	neutral	0,58	deleterious	-6,26	neutral	-1,95	high_impact	4,8	damaging	0,59	neutral	0,55	deleterious	3,6	23,2	0,06	0,35	disease	0,62	disease	0,58	disease	0,74	disease	0,7	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,77	low_impact	-3,78	medium_impact	-0,3	high_impact	3,12	0,43	0,8	73,56	11,67	P	0,69	P	0,85	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9615	9615	T	G	MI.7497	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	409	137	L	V	Tta/Gta	-10,28	0	0,01	probably_damaging	0,98	neutral	0,36	neutral	0,58	deleterious	-6,21	deleterious	-2,92	high_impact	4,8	damaging	0,47	neutral	0,38	deleterious	3,45	23	0,05	0,35	disease	0,54	disease	0,61	disease	0,76	disease	0,71	4	neutral	0,98	neutral	0,19	deleterious	2	deleterious	0,77	low_impact	-2,51	medium_impact	0,05	high_impact	3,12	0,55	0,8	73,56	11,67	P	0,65	P	0,81	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9616	9616	T	C	MI.7498	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	410	137	L	S	tTa/tCa	0,13	0	0	probably_damaging	1	neutral	0,81	neutral	0,52	deleterious	-10,18	deleterious	-5,85	high_impact	4,8	damaging	0,5	neutral	0,44	deleterious	3,82	23,4	0,02	0,35	disease	0,82	disease	0,8	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,41	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	0,55	high_impact	3,12	0,22	0,8	73,56	11,67	P	0,57	P	0,92	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9616	9616	T	G	MI.7499	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	410	137	L	W	tTa/tGa	0,13	0	0	probably_damaging	1	deleterious	0,01	neutral	0,52	deleterious	-10,27	deleterious	-5,85	high_impact	4,8	damaging	0,59	neutral	0,37	deleterious	3,77	23,4	0,03	0,35	disease	0,92	disease	0,74	disease	0,77	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-3,78	medium_impact	-0,95	high_impact	3,12	0,2	0,8	73,56	11,67	P	0,58	P	1	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8558	8558	C	T	MI.75	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	32	11	A	V	gCc/gTc	1,05	0,01	0	benign	0,19	neutral	0,11	neutral	4,65	neutral	-0,5	neutral	-1,14	neutral_impact	0	neutral	0,96	neutral	0,94	deleterious	4,14	23,8	0,37	0,65	disease	0,57	disease	0,59	neutral	0,36	disease	0,51	0	neutral	0,87	neutral	0,46	neutral	-6	neutral	0,3	medium_impact	-0,16	medium_impact	-0,22	low_impact	-1,1	0,65	0,9	23,45	19,76	P	0,57	P	0,48	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	C8558T	Possibly LVNC cardiomyopathy-associated	+	-	Reported	1
chrM	8879	8879	G	A	MI.750	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	353	118	R	H	cGc/cAc	0,59	0,43	0	probably_damaging	1	neutral	0,54	neutral	4,32	neutral	-2,88	deleterious	-4,56	medium_impact	3,37	neutral	0,66	neutral	0,29	deleterious	4,42	24,2	0,36	0,65	disease	0,78	disease	0,85	neutral	0,49	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,85	low_impact	-3,6	medium_impact	0,33	medium_impact	1,79	0,77	0,9	47,35	8,78	N	0,26	N	1	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9617	9617	A	T	MI.7500	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	411	137	L	F	ttA/ttT	7,53	0,97	0	probably_damaging	1	deleterious	0,04	neutral	0,57	deleterious	-6,52	deleterious	-3,9	high_impact	4,8	damaging	0,46	neutral	0,4	deleterious	3,62	23,2	0,04	0,35	disease	0,64	disease	0,72	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-3,78	medium_impact	-0,6	high_impact	3,12	0,42	0,8	73,56	11,67	P	0,76	P	0,95	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9617	9617	A	C	MI.7501	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	411	137	L	F	ttA/ttC	7,53	0,97	0	probably_damaging	1	deleterious	0,04	neutral	0,57	deleterious	-6,52	deleterious	-3,9	high_impact	4,8	damaging	0,46	neutral	0,4	deleterious	3,48	23,1	0,04	0,35	disease	0,64	disease	0,72	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-3,78	medium_impact	-0,6	high_impact	3,12	0,42	0,8	73,56	11,67	P	0,76	P	0,95	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9618	9618	C	G	MI.7502	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	412	138	L	V	Ctc/Gtc	-15,6	0	0	probably_damaging	0,91	neutral	0,68	neutral	1,76	neutral	-2,19	deleterious	-2,79	low_impact	1,91	damaging	0,55	damaging	0,04	deleterious	3,48	23,1	0,23	0,45	neutral	0,22	disease	0,58	disease	0,63	neutral	0,38	2	neutral	0,9	neutral	0,39	neutral	-2	deleterious	0,64	low_impact	-1,85	medium_impact	0,38	medium_impact	0,53	0,54	0,8	73,95	11,76	N	0,2	N	0,81	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9618	9618	C	A	MI.7503	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	412	138	L	I	Ctc/Atc	-15,6	0	0	probably_damaging	0,96	neutral	0,68	neutral	1,77	neutral	-2,07	neutral	-1,82	medium_impact	2,38	damaging	0,55	damaging	0,08	deleterious	4,11	23,7	0,27	0,45	neutral	0,29	disease	0,53	neutral	0,47	neutral	0,2	6	neutral	0,96	neutral	0,36	deleterious	1	deleterious	0,66	low_impact	-2,21	medium_impact	0,38	medium_impact	0,95	0,52	0,8	73,95	11,76	N	0,23	N	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9618	9618	C	T	MI.7504	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	412	138	L	F	Ctc/Ttc	-15,6	0	0	probably_damaging	0,99	neutral	0,1	neutral	1,61	deleterious	-4,05	deleterious	-3,84	high_impact	4,04	damaging	0,57	damaging	0,02	deleterious	4,01	23,6	0,16	0,45	neutral	0,43	disease	0,76	disease	0,69	disease	0,66	3	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,78	low_impact	-2,81	medium_impact	-0,35	high_impact	2,44	0,47	0,8	73,95	11,76	N	0,27	N	0,95	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9619	9619	T	C	MI.7505	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	413	138	L	P	cTc/cCc	-0,1	0	0	probably_damaging	1	neutral	0,06	neutral	1,56	deleterious	-6,4	deleterious	-6,76	high_impact	4,04	damaging	0,52	damaging	0,03	deleterious	4	23,6	0,01	0,35	neutral	0,49	disease	0,83	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,49	high_impact	2,44	0,36	0,8	73,95	11,76	N	0,35	N	0,99	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9619	9619	T	G	MI.7506	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	413	138	L	R	cTc/cGc	-0,1	0	0	probably_damaging	0,99	neutral	0,05	neutral	1,57	deleterious	-5,71	deleterious	-5,82	high_impact	4,59	neutral	0,65	damaging	0,03	deleterious	4,24	23,9	0,01	0,35	disease	0,55	disease	0,87	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,85	low_impact	-2,81	medium_impact	-0,54	high_impact	2,93	0,17	0,8	73,95	11,76	N	0,49	N	0,99	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9619	9619	T	A	MI.7507	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	413	138	L	H	cTc/cAc	-0,1	0	0	probably_damaging	1	deleterious	0,03	neutral	1,56	deleterious	-6,61	deleterious	-6,76	high_impact	4,59	damaging	0,6	damaging	0,02	deleterious	4,27	23,9	0,03	0,35	disease	0,65	disease	0,83	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,83	low_impact	-3,78	medium_impact	-0,67	high_impact	2,93	0,26	0,8	73,95	11,76	N	0,42	N	0,97	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9621	9621	G	A	MI.7508	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	415	139	A	T	Gca/Aca	-1,03	0	0	probably_damaging	1	neutral	0,39	neutral	2,6	neutral	0,54	neutral	-1,05	neutral_impact	0,71	neutral	0,64	neutral	0,7	deleterious	3,12	22,6	0,14	0,4	neutral	0,17	neutral	0,37	neutral	0,39	neutral	0,43	1	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,68	low_impact	-3,78	medium_impact	0,08	medium_impact	-0,55	0,8	0,85	73,18	11,54	N	0,42	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9621	9621	G	C	MI.7509	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	415	139	A	P	Gca/Cca	-1,03	0	0	probably_damaging	1	neutral	0,2	neutral	2,45	deleterious	-3,42	deleterious	-3,09	medium_impact	2,77	damaging	0,54	neutral	0,38	deleterious	3,86	23,5	0,03	0,35	disease	0,5	disease	0,84	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,83	low_impact	-3,78	medium_impact	-0,15	medium_impact	1,3	0,62	0,8	73,18	11,54	N	0,33	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8879	8879	G	T	MI.751	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	353	118	R	L	cGc/cTc	0,59	0,43	0	probably_damaging	0,99	neutral	0,66	neutral	4,38	neutral	-2,12	deleterious	-6,32	low_impact	1,51	neutral	0,71	neutral	0,39	deleterious	4,31	24	0,3	0,65	disease	0,74	disease	0,92	disease	0,53	disease	0,54	1	deleterious	0,99	neutral	0,34	neutral	-2	deleterious	0,87	low_impact	-2,65	medium_impact	0,45	medium_impact	0,2	0,35	0,9	47,35	8,78	N	0,22	N	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9621	9621	G	T	MI.7510	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	415	139	A	S	Gca/Tca	-1,03	0	0	probably_damaging	1	neutral	0,45	neutral	2,65	neutral	-0,05	neutral	-0,13	neutral_impact	-0,3	neutral	0,62	neutral	0,66	deleterious	2,41	18,86	0,24	0,45	neutral	0,17	neutral	0,14	neutral	0,3	neutral	0,22	6	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,66	low_impact	-3,78	medium_impact	0,14	low_impact	-1,45	0,53	0,8	73,18	11,54	N	0,41	N	0,89	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9622	9622	C	T	MI.7511	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	416	139	A	V	gCa/gTa	9,38	1	0	probably_damaging	1	neutral	0,52	neutral	2,54	neutral	-0,45	deleterious	-2,82	medium_impact	2,05	damaging	0,57	neutral	0,63	deleterious	4,55	24,3	0,12	0,4	neutral	0,2	disease	0,6	disease	0,64	disease	0,69	4	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,7	low_impact	-3,78	medium_impact	0,21	medium_impact	0,66	0,78	0,85	73,18	11,54	P	0,58	P	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9622	9622	C	G	MI.7512	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	416	139	A	G	gCa/gGa	9,38	1	0	probably_damaging	0,99	neutral	0,35	neutral	2,46	neutral	-2,29	neutral	-2,2	low_impact	1,5	damaging	0,58	neutral	0,62	deleterious	3,97	23,6	0,22	0,45	neutral	0,41	disease	0,53	disease	0,56	neutral	0,33	3	deleterious	0,99	neutral	0,18	neutral	-2	deleterious	0,71	low_impact	-2,81	medium_impact	0,04	medium_impact	0,16	0,68	0,85	73,18	11,54	P	0,51	P	0,67	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9622	9622	C	A	MI.7513	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	416	139	A	E	gCa/gAa	9,38	1	0	probably_damaging	1	neutral	0,27	neutral	2,45	neutral	-2,61	deleterious	-2,8	medium_impact	3,23	damaging	0,56	neutral	0,4	deleterious	4,58	24,4	0,03	0,35	neutral	0,32	disease	0,82	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,78	low_impact	-3,78	medium_impact	-0,06	medium_impact	1,71	0,33	0,8	73,18	11,54	P	0,56	P	0,97	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9624	9624	T	C	MI.7514	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	418	140	S	P	Tca/Cca	-6,81	0	0	probably_damaging	0,99	neutral	0,26	neutral	1,21	deleterious	-7,13	deleterious	-4,87	high_impact	4,09	damaging	0,5	damaging	0,06	deleterious	4,03	23,6	0,03	0,35	disease	0,78	disease	0,82	disease	0,87	disease	0,73	5	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,87	low_impact	-2,81	medium_impact	-0,07	high_impact	2,48	0,28	0,8	73,56	11,73	N	0,39	N	0,98	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9624	9624	T	G	MI.7515	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	418	140	S	A	Tca/Gca	-6,81	0	0	probably_damaging	0,96	neutral	0,61	neutral	1,36	deleterious	-3,79	deleterious	-2,92	high_impact	4,79	damaging	0,57	damaging	0,1	deleterious	3,78	23,4	0,07	0,35	neutral	0,49	disease	0,61	disease	0,75	disease	0,71	4	neutral	0,95	neutral	0,33	deleterious	2	deleterious	0,68	low_impact	-2,21	medium_impact	0,3	high_impact	3,11	0,4	0,8	73,56	11,73	P	0,63	P	0,4	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9624	9624	T	A	MI.7516	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	418	140	S	T	Tca/Aca	-6,81	0	0	probably_damaging	0,92	neutral	0,46	neutral	1,3	deleterious	-4,47	deleterious	-2,92	high_impact	3,82	damaging	0,55	damaging	0,04	deleterious	3,85	23,4	0,08	0,35	disease	0,61	disease	0,68	disease	0,79	disease	0,69	4	neutral	0,92	neutral	0,27	deleterious	2	deleterious	0,77	low_impact	-1,9	medium_impact	0,15	high_impact	2,24	0,51	0,8	73,56	11,73	N	0,37	N	0,63	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9625	9625	C	G	MI.7517	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	419	140	S	W	tCa/tGa	7,53	1	0	probably_damaging	1	neutral	0,17	neutral	1,2	deleterious	-10,15	deleterious	-6,82	high_impact	4,79	neutral	0,63	damaging	0,03	deleterious	4,35	24,1	0,03	0,35	disease	0,95	disease	0,89	disease	0,81	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,78	medium_impact	-0,2	high_impact	3,11	0,12	0,8	73,56	11,73	P	0,62	P	1	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9625	9625	C	T	MI.7518	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	419	140	S	L	tCa/tTa	7,53	1	0	probably_damaging	0,99	neutral	0,75	neutral	1,21	deleterious	-7,42	deleterious	-5,85	high_impact	4,79	damaging	0,56	damaging	0,03	deleterious	4,63	24,5	0,02	0,35	disease	0,78	disease	0,86	disease	0,75	disease	0,7	4	deleterious	0,99	neutral	0,38	deleterious	2	deleterious	0,86	low_impact	-2,81	medium_impact	0,46	high_impact	3,11	0,49	0,8	73,56	11,73	P	0,7	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9627	9627	G	C	MI.7519	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	421	141	G	R	Gga/Cga	-12,13	0	0	probably_damaging	1	neutral	0,24	neutral	0,9	deleterious	-6,58	deleterious	-7,8	high_impact	4,58	neutral	0,6	damaging	0,02	deleterious	4,02	23,6	0,02	0,35	neutral	0,42	disease	0,82	disease	0,83	disease	0,74	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,09	high_impact	2,92	0,7	0,85	74,33	11,54	N	0,44	N	0,99	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8879	8879	G	C	MI.752	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	353	118	R	P	cGc/cCc	0,59	0,43	0	probably_damaging	1	neutral	0,2	neutral	4,32	deleterious	-3,37	deleterious	-6,4	high_impact	3,71	damaging	0,6	neutral	0,33	deleterious	4,21	23,9	0,13	0,65	disease	0,81	disease	0,95	disease	0,76	disease	0,84	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,6	medium_impact	-0,05	high_impact	2,08	0,37	0,9	47,35	8,78	N	0,38	N	1	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9627	9627	G	T	MI.7520	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	421	141	G	W	Gga/Tga	-12,13	0	0	probably_damaging	1	neutral	0,13	neutral	0,88	deleterious	-9,11	deleterious	-7,8	high_impact	4,58	damaging	0,58	damaging	0,02	deleterious	4,46	24,2	0,03	0,35	disease	0,83	disease	0,87	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,88	low_impact	-3,78	medium_impact	-0,28	high_impact	2,92	0,15	0,8	74,33	11,54	N	0,4	N	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9628	9628	G	T	MI.7521	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	422	141	G	V	gGa/gTa	7,3	1	0	probably_damaging	1	neutral	0,48	neutral	0,9	deleterious	-6,37	deleterious	-8,77	high_impact	3,77	damaging	0,51	damaging	0,01	deleterious	3,79	23,4	0,03	0,35	neutral	0,38	disease	0,83	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	0,17	high_impact	2,2	0,17	0,8	74,33	11,54	N	0,46	N	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9628	9628	G	C	MI.7522	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	422	141	G	A	gGa/gCa	7,3	1	0	probably_damaging	1	neutral	0,45	neutral	0,95	deleterious	-4,99	deleterious	-5,85	medium_impact	3,48	damaging	0,56	damaging	0,01	deleterious	3,16	22,6	0,08	0,35	neutral	0,2	disease	0,64	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,76	low_impact	-3,78	medium_impact	0,14	medium_impact	1,94	0,49	0,8	74,33	11,54	N	0,44	N	0,3	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9628	9628	G	A	MI.7523	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	422	141	G	E	gGa/gAa	7,3	1	0	probably_damaging	1	neutral	0,19	neutral	0,91	deleterious	-5,97	deleterious	-7,8	high_impact	4,58	damaging	0,49	damaging	0,01	deleterious	3,92	23,5	0,02	0,35	neutral	0,33	disease	0,85	disease	0,82	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,17	high_impact	2,92	0,24	0,8	74,33	11,54	P	0,53	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9630	9630	G	A	MI.7524	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	424	142	V	M	Gta/Ata	-3,8	0	0	possibly_damaging	0,72	neutral	0,21	neutral	2,08	neutral	-2,52	neutral	-2,06	medium_impact	2,25	neutral	0,62	neutral	0,66	deleterious	3,7	23,3	0,17	0,45	neutral	0,3	disease	0,53	neutral	0,39	neutral	0,36	3	neutral	0,84	neutral	0,25	NA	0	deleterious	0,55	low_impact	-1,27	medium_impact	-0,14	medium_impact	0,83	0,92	0,95	75,1	11,19	N	0,41	N	0,96	polymorphism	1	0,03	.	.	.	.	.	.	COSM1138440	.	.	.	.	.	.	.	.
chrM	9630	9630	G	C	MI.7525	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	424	142	V	L	Gta/Cta	-3,8	0	0	benign	0,04	neutral	0,65	neutral	2,2	neutral	-0,24	neutral	-1,84	low_impact	1,76	neutral	0,64	neutral	0,73	deleterious	1,85	15,27	0,18	0,45	neutral	0,11	disease	0,6	neutral	0,37	neutral	0,33	4	neutral	0,3	deleterious	0,81	neutral	-6	neutral	0,16	medium_impact	0,47	medium_impact	0,35	medium_impact	0,4	0,6	0,8	75,1	11,19	N	0,34	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9630	9630	G	T	MI.7526	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	424	142	V	L	Gta/Tta	-3,8	0	0	benign	0,04	neutral	0,65	neutral	2,2	neutral	-0,24	neutral	-1,84	low_impact	1,76	neutral	0,64	neutral	0,73	deleterious	1,97	16,02	0,18	0,45	neutral	0,11	disease	0,6	neutral	0,37	neutral	0,33	4	neutral	0,3	deleterious	0,81	neutral	-6	neutral	0,16	medium_impact	0,47	medium_impact	0,35	medium_impact	0,4	0,6	0,8	75,1	11,19	N	0,34	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9631	9631	T	G	MI.7527	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	425	142	V	G	gTa/gGa	7,53	1	0	possibly_damaging	0,83	neutral	0,48	neutral	2,05	neutral	-2,04	deleterious	-5,7	medium_impact	2,35	neutral	0,6	neutral	0,57	deleterious	3,83	23,4	0,04	0,35	neutral	0,32	disease	0,73	disease	0,6	disease	0,61	2	neutral	0,82	neutral	0,33	NA	0	deleterious	0,68	low_impact	-1,54	medium_impact	0,17	medium_impact	0,92	0,16	0,8	75,1	11,19	N	0,48	N	0,88	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9631	9631	T	C	MI.7528	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	425	142	V	A	gTa/gCa	7,53	1	0	benign	0,4	neutral	0,61	neutral	2,22	neutral	-1,09	deleterious	-2,74	neutral_impact	0,79	neutral	0,71	neutral	0,73	deleterious	2,37	18,6	0,11	0,4	neutral	0,14	neutral	0,23	neutral	0,36	neutral	0,39	2	neutral	0,35	deleterious	0,61	neutral	-6	neutral	0,31	medium_impact	-0,7	medium_impact	0,3	medium_impact	-0,48	0,22	0,8	75,1	11,19	P	0,51	P	0,39	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9631	9631	T	A	MI.7529	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	425	142	V	E	gTa/gAa	7,53	1	0	possibly_damaging	0,78	neutral	0,26	neutral	2,06	deleterious	-3,89	deleterious	-4,99	high_impact	3,96	damaging	0,6	neutral	0,44	deleterious	4,84	24,8	0,03	0,35	neutral	0,4	disease	0,87	disease	0,73	disease	0,74	5	neutral	0,84	neutral	0,24	deleterious	1	deleterious	0,71	low_impact	-1,4	medium_impact	-0,07	high_impact	2,37	0,15	0,8	75,1	11,19	P	0,63	P	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8881	8881	T	C	MI.753	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	355	119	S	P	Tct/Cct	-2,42	0	0	benign	0,21	neutral	0,06	neutral	4,3	neutral	-2,46	neutral	-2,21	low_impact	1,38	neutral	0,73	neutral	0,42	deleterious	2,12	16,95	0,28	0,65	disease	0,79	disease	0,91	disease	0,56	disease	0,73	5	neutral	0,93	neutral	0,43	neutral	-6	deleterious	0,49	medium_impact	-0,21	medium_impact	-0,38	medium_impact	0,09	0,55	0,9	24,34	26,09	N	0,29	N	0,23	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9633	9633	T	G	MI.7530	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	427	143	S	A	Tca/Gca	-20	0	0	benign	0,04	neutral	0,52	neutral	2,59	neutral	0,68	neutral	-1,28	low_impact	1,58	neutral	0,64	neutral	0,57	deleterious	1,88	15,45	0,28	0,45	neutral	0,15	neutral	0,41	neutral	0,48	neutral	0,44	1	neutral	0,44	deleterious	0,74	neutral	-6	neutral	0,17	medium_impact	0,47	medium_impact	0,21	medium_impact	0,23	0,56	0,8	20,31	43,72	N	0,39	N	0,39	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9633	9633	T	A	MI.7531	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	427	143	S	T	Tca/Aca	-20	0	0	benign	0	neutral	1	neutral	2,85	neutral	3,14	neutral	2,84	neutral_impact	-1,1	neutral	0,73	neutral	0,89	neutral	-0,9	0,03	0,25	0,45	neutral	0,13	neutral	0,07	neutral	0,39	neutral	0,2	6	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,05	high_impact	1,9	low_impact	-2,17	0,58	0,8	20,31	43,72	N	0,36	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9633	9633	T	C	MI.7532	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	427	143	S	P	Tca/Cca	-20	0	0	benign	0,21	neutral	0,1	neutral	2,52	neutral	-1,68	neutral	-2,4	medium_impact	2,27	damaging	0,42	neutral	0,33	deleterious	3,62	23,2	0,05	0,35	neutral	0,48	disease	0,88	disease	0,77	disease	0,76	5	neutral	0,88	neutral	0,45	neutral	-3	deleterious	0,45	medium_impact	-0,31	medium_impact	-0,35	medium_impact	0,85	0,33	0,8	20,31	43,72	N	0,46	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9634	9634	C	G	MI.7533	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	428	143	S	W	tCa/tGa	3,37	0,99	0	possibly_damaging	0,88	neutral	0,24	neutral	2,5	neutral	-2,71	deleterious	-3,53	medium_impact	2,51	damaging	0,54	neutral	0,41	deleterious	4,29	24	0,05	0,35	disease	0,79	disease	0,88	disease	0,7	disease	0,74	5	neutral	0,92	neutral	0,18	NA	0	deleterious	0,82	low_impact	-1,71	medium_impact	-0,09	medium_impact	1,07	0,18	0,8	20,31	43,72	N	0,42	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9634	9634	C	T	MI.7534	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	428	143	S	L	tCa/tTa	3,37	0,99	0	benign	0,18	neutral	0,43	neutral	2,63	neutral	0,83	deleterious	-2,56	medium_impact	2,42	damaging	0,57	neutral	0,41	deleterious	3,06	22,4	0,08	0,35	neutral	0,32	disease	0,76	disease	0,62	disease	0,71	4	neutral	0,49	deleterious	0,63	neutral	-3	neutral	0,3	medium_impact	-0,23	medium_impact	0,12	medium_impact	0,99	0,4	0,8	20,31	43,72	N	0,39	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9636	9636	A	C	MI.7535	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	430	144	I	L	Atc/Ctc	-9,82	0	0	probably_damaging	0,95	neutral	0,72	neutral	2,13	neutral	-1,01	neutral	-1,88	low_impact	1,06	damaging	0,52	damaging	0,08	deleterious	3,56	23,1	0,25	0,45	neutral	0,17	neutral	0,4	neutral	0,42	neutral	0,44	1	neutral	0,94	neutral	0,39	neutral	-2	neutral	0,39	low_impact	-2,11	medium_impact	0,43	medium_impact	-0,23	0,48	0,8	75,86	11,24	N	0,25	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9636	9636	A	T	MI.7536	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	430	144	I	F	Atc/Ttc	-9,82	0	0	probably_damaging	0,99	neutral	0,7	neutral	1,95	deleterious	-3,53	deleterious	-3,83	medium_impact	2,02	damaging	0,47	damaging	0,02	deleterious	3,89	23,5	0,15	0,4	neutral	0,35	disease	0,67	disease	0,66	disease	0,7	4	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,73	low_impact	-2,81	medium_impact	0,4	medium_impact	0,63	0,56	0,8	75,86	11,24	N	0,25	N	0,94	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9636	9636	A	G	MI.7537	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	430	144	I	V	Atc/Gtc	-9,82	0	0	possibly_damaging	0,87	neutral	0,67	neutral	2,51	neutral	0,64	neutral	0,38	neutral_impact	-0,97	neutral	0,62	neutral	0,49	neutral	-1,33	0	0,37	0,5	neutral	0,11	neutral	0,04	neutral	0,33	neutral	0,18	6	neutral	0,84	neutral	0,4	neutral	-3	neutral	0,42	low_impact	-1,67	medium_impact	0,37	low_impact	-2,05	0,4	0,8	75,86	11,24	N	0,31	N	0,62	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9637	9637	T	C	MI.7538	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	431	144	I	T	aTc/aCc	2,67	0,99	0	probably_damaging	1	neutral	0,62	neutral	1,96	deleterious	-3,28	deleterious	-3,47	medium_impact	3,29	damaging	0,5	damaging	0,03	deleterious	3,22	22,7	0,06	0,35	neutral	0,3	neutral	0,47	disease	0,62	disease	0,54	1	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,7	low_impact	-3,78	medium_impact	0,31	medium_impact	1,77	0,21	0,8	75,86	11,24	N	0,39	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9637	9637	T	A	MI.7539	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	431	144	I	N	aTc/aAc	2,67	0,99	0	probably_damaging	1	neutral	0,31	neutral	1,93	deleterious	-5,07	deleterious	-6,07	medium_impact	3,29	damaging	0,49	damaging	0,02	deleterious	4,61	24,4	0,06	0,35	disease	0,54	disease	0,74	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,79	low_impact	-3,78	medium_impact	-0,01	medium_impact	1,77	0,38	0,8	75,86	11,24	N	0,39	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8881	8881	T	A	MI.754	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	355	119	S	T	Tct/Act	-2,42	0	0	benign	0,04	neutral	0,17	neutral	4,36	neutral	-0,38	neutral	-0,62	neutral_impact	-0,4	neutral	0,92	neutral	0,87	deleterious	0,84	9,68	0,45	0,65	disease	0,62	neutral	0,41	neutral	0,15	disease	0,61	2	neutral	0,82	deleterious	0,57	neutral	-6	neutral	0,24	medium_impact	0,55	medium_impact	-0,1	low_impact	-1,44	0,83	0,9	24,34	26,09	N	0,44	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9637	9637	T	G	MI.7540	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	431	144	I	S	aTc/aGc	2,67	0,99	0	probably_damaging	1	neutral	0,43	neutral	1,94	deleterious	-4,06	deleterious	-5,09	medium_impact	2,15	damaging	0,47	damaging	0,04	deleterious	4,31	24	0,03	0,35	neutral	0,26	disease	0,71	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	0,12	medium_impact	0,74	0,32	0,8	75,86	11,24	N	0,34	N	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9638	9638	C	A	MI.7541	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	432	144	I	M	atC/atA	7,53	1	0	probably_damaging	1	neutral	0,22	neutral	1,96	deleterious	-3,23	neutral	-2,11	low_impact	1,53	damaging	0,52	damaging	0,04	deleterious	3,8	23,4	0,21	0,45	neutral	0,17	neutral	0,42	disease	0,56	neutral	0,47	1	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,66	low_impact	-3,78	medium_impact	-0,12	medium_impact	0,19	0,55	0,8	75,86	11,24	N	0,5	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9638	9638	C	G	MI.7542	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	432	144	I	M	atC/atG	7,53	1	0	probably_damaging	1	neutral	0,22	neutral	1,96	deleterious	-3,23	neutral	-2,11	low_impact	1,53	damaging	0,52	damaging	0,04	deleterious	3,38	22,9	0,21	0,45	neutral	0,17	neutral	0,42	disease	0,56	neutral	0,47	1	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,66	low_impact	-3,78	medium_impact	-0,12	medium_impact	0,19	0,55	0,8	75,86	11,24	N	0,5	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9639	9639	A	C	MI.7543	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	433	145	T	P	Acc/Ccc	-9,82	0	0	probably_damaging	0,99	neutral	0,19	neutral	1,54	deleterious	-5,26	deleterious	-5,84	high_impact	4,59	neutral	0,67	damaging	0,05	deleterious	3,5	23,1	0,04	0,35	neutral	0,48	disease	0,79	disease	0,77	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,79	low_impact	-2,81	medium_impact	-0,17	high_impact	2,93	0,45	0,8	73,95	11,6	N	0,45	N	0,98	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9639	9639	A	T	MI.7544	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	433	145	T	S	Acc/Tcc	-9,82	0	0	probably_damaging	0,96	neutral	0,39	neutral	1,61	deleterious	-3,47	deleterious	-3,88	medium_impact	3,49	neutral	0,69	damaging	0,03	deleterious	3,32	22,9	0,28	0,45	neutral	0,25	disease	0,69	disease	0,57	disease	0,53	1	neutral	0,96	neutral	0,22	deleterious	1	deleterious	0,71	low_impact	-2,21	medium_impact	0,08	medium_impact	1,95	0,66	0,8	73,95	11,6	N	0,25	N	0,77	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9639	9639	A	G	MI.7545	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	433	145	T	A	Acc/Gcc	-9,82	0	0	probably_damaging	0,96	neutral	0,56	neutral	1,63	deleterious	-3,15	deleterious	-4,86	medium_impact	3,17	neutral	0,65	damaging	0,04	deleterious	3,55	23,1	0,2	0,45	neutral	0,16	disease	0,64	disease	0,64	disease	0,66	3	neutral	0,95	neutral	0,3	deleterious	1	deleterious	0,67	low_impact	-2,21	medium_impact	0,25	medium_impact	1,66	0,53	0,8	73,95	11,6	N	0,22	N	0,44	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9640	9640	C	G	MI.7546	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	434	145	T	S	aCc/aGc	8,69	1	0	probably_damaging	0,96	neutral	0,39	neutral	1,61	deleterious	-3,47	deleterious	-3,88	medium_impact	3,49	neutral	0,69	damaging	0,03	deleterious	3,55	23,1	0,28	0,45	neutral	0,25	disease	0,69	disease	0,57	disease	0,53	1	neutral	0,96	neutral	0,22	deleterious	1	deleterious	0,71	low_impact	-2,21	medium_impact	0,08	medium_impact	1,95	0,66	0,8	73,95	11,6	N	0,46	N	0,77	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9640	9640	C	T	MI.7547	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	434	145	T	I	aCc/aTc	8,69	1	0	probably_damaging	1	neutral	0,41	neutral	1,56	deleterious	-4,36	deleterious	-5,84	high_impact	4,04	neutral	0,7	damaging	0,02	deleterious	4,05	23,7	0,06	0,35	neutral	0,28	disease	0,88	disease	0,62	disease	0,69	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	0,1	high_impact	2,44	0,74	0,85	73,95	11,6	N	0,44	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9640	9640	C	A	MI.7548	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	434	145	T	N	aCc/aAc	8,69	1	0	probably_damaging	0,99	neutral	0,3	neutral	1,55	deleterious	-4,72	deleterious	-4,86	medium_impact	2,96	neutral	0,67	damaging	0,03	deleterious	3,75	23,3	0,21	0,45	neutral	0,33	disease	0,78	disease	0,67	disease	0,67	3	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,73	low_impact	-2,81	medium_impact	-0,02	medium_impact	1,47	0,61	0,8	73,95	11,6	N	0,41	N	0,89	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9642	9642	T	G	MI.7549	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	436	146	W	G	Tga/Gga	-5,42	0	0	probably_damaging	1	neutral	0,33	neutral	2,18	neutral	-2,55	deleterious	-12,67	high_impact	4,14	neutral	0,62	damaging	0,02	deleterious	3,99	23,6	0,05	0,35	neutral	0,38	disease	0,86	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	0,02	high_impact	2,53	0,17	0,8	75,1	11,59	N	0,4	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8881	8881	T	G	MI.755	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	355	119	S	A	Tct/Gct	-2,42	0	0	benign	0,01	neutral	0,17	neutral	4,36	neutral	-0,09	neutral	-1,59	neutral_impact	0,24	neutral	0,87	neutral	0,77	neutral	1,72	14,53	0,42	0,65	disease	0,53	neutral	0,47	neutral	0,27	neutral	0,45	1	neutral	0,83	deleterious	0,58	neutral	-6	neutral	0,22	medium_impact	1,14	medium_impact	-0,1	medium_impact	-0,89	0,59	0,9	24,34	26,09	N	0,38	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9642	9642	T	C	MI.7550	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	436	146	W	R	Tga/Cga	-5,42	0	0	probably_damaging	1	neutral	0,35	neutral	2,19	neutral	-2,02	deleterious	-13,64	medium_impact	3,1	neutral	0,72	damaging	0,03	deleterious	3,6	23,2	0,03	0,35	neutral	0,34	disease	0,9	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,81	low_impact	-3,78	medium_impact	0,04	medium_impact	1,6	0,26	0,8	75,1	11,59	N	0,38	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9643	9643	G	T	MI.7551	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	437	146	W	L	tGa/tTa	5,91	1	0	probably_damaging	1	neutral	0,66	neutral	2,29	neutral	-0,26	deleterious	-12,67	medium_impact	2,51	neutral	0,61	damaging	0,02	deleterious	4,35	24,1	0,09	0,35	neutral	0,11	disease	0,84	disease	0,71	disease	0,57	1	deleterious	0,99	neutral	0,33	deleterious	1	deleterious	0,74	low_impact	-3,78	medium_impact	0,36	medium_impact	1,07	0,17	0,8	75,1	11,59	N	0,34	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9643	9643	G	C	MI.7552	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	437	146	W	S	tGa/tCa	5,91	1	0	probably_damaging	1	neutral	0,43	neutral	2,21	neutral	-1,48	deleterious	-13,64	high_impact	3,52	neutral	0,65	damaging	0,02	deleterious	4,07	23,7	0,05	0,35	neutral	0,24	disease	0,91	disease	0,71	disease	0,68	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	0,12	medium_impact	1,97	0,23	0,8	75,1	11,59	N	0,4	N	0,97	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9644	9644	A	C	MI.7553	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	438	146	W	C	tgA/tgC	9,38	1	0,02	probably_damaging	1	neutral	0,18	neutral	2,17	deleterious	-3,37	deleterious	-12,67	high_impact	3,8	neutral	0,67	damaging	0,02	deleterious	4,08	23,7	0,04	0,35	neutral	0,45	disease	0,9	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	-0,18	high_impact	2,22	0,21	0,8	75,1	11,59	N	0,48	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9644	9644	A	T	MI.7554	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	438	146	W	C	tgA/tgT	9,38	1	0,02	probably_damaging	1	neutral	0,18	neutral	2,17	deleterious	-3,37	deleterious	-12,67	high_impact	3,8	neutral	0,67	damaging	0,02	deleterious	4,19	23,8	0,04	0,35	neutral	0,45	disease	0,9	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	-0,18	high_impact	2,22	0,21	0,8	75,1	11,59	N	0,49	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9645	9645	G	C	MI.7555	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	439	147	A	P	Gct/Cct	0,59	0,99	0	probably_damaging	1	neutral	0,2	neutral	2	deleterious	-5,48	deleterious	-4,56	high_impact	4,43	damaging	0,56	damaging	0,03	deleterious	3,85	23,4	0,02	0,35	disease	0,7	disease	0,87	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,78	medium_impact	-0,15	high_impact	2,79	0,52	0,8	78,16	10,08	P	0,51	P	0,95	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9645	9645	G	A	MI.7556	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	439	147	A	T	Gct/Act	0,59	0,99	0	probably_damaging	0,99	neutral	0,41	neutral	2,04	deleterious	-3,78	deleterious	-3,47	medium_impact	3,12	damaging	0,51	damaging	0,18	deleterious	2,26	17,89	0,05	0,35	neutral	0,48	disease	0,76	disease	0,53	neutral	0,25	5	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,81	low_impact	-2,81	medium_impact	0,1	medium_impact	1,61	0,63	0,8	78,16	10,08	N	0,45	N	0,78	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9645	9645	G	T	MI.7557	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	439	147	A	S	Gct/Tct	0,59	0,99	0	probably_damaging	0,99	neutral	0,42	neutral	2,12	neutral	-2,46	neutral	-2,31	low_impact	1,3	damaging	0,51	damaging	0,19	deleterious	2,36	18,58	0,08	0,35	neutral	0,33	disease	0,54	neutral	0,37	neutral	0,21	6	deleterious	0,99	neutral	0,22	neutral	-2	deleterious	0,77	low_impact	-2,81	medium_impact	0,11	medium_impact	-0,02	0,53	0,8	78,16	10,08	N	0,42	N	0,3	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9646	9646	C	T	MI.7558	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	440	147	A	V	gCt/gTt	5,22	1	0	probably_damaging	0,99	neutral	0,5	neutral	2,07	deleterious	-3,89	deleterious	-3,78	high_impact	4,43	damaging	0,55	damaging	0,03	deleterious	4,07	23,7	0,04	0,35	neutral	0,45	disease	0,79	disease	0,61	disease	0,65	3	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,79	low_impact	-2,81	medium_impact	0,19	high_impact	2,79	0,65	0,8	78,16	10,08	P	0,53	P	0,72	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9646	9646	C	A	MI.7559	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	440	147	A	D	gCt/gAt	5,22	1	0	probably_damaging	1	neutral	0,2	neutral	2	deleterious	-4,77	deleterious	-5,33	high_impact	4,43	damaging	0,56	damaging	0,02	deleterious	4,53	24,3	0,02	0,35	disease	0,76	disease	0,9	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	-0,15	high_impact	2,79	0,35	0,8	78,16	10,08	P	0,57	P	0,99	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8882	8882	C	G	MI.756	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	356	119	S	C	tCt/tGt	0,36	0	0	benign	0,37	neutral	0,1	neutral	4,31	deleterious	-4,18	neutral	-2,27	low_impact	1,04	neutral	0,9	neutral	0,45	deleterious	1,87	15,42	0,4	0,65	disease	0,93	disease	0,78	neutral	0,42	disease	0,74	5	neutral	0,88	neutral	0,37	neutral	-6	deleterious	0,56	medium_impact	-0,54	medium_impact	-0,25	medium_impact	-0,21	0,61	0,9	24,34	26,09	N	0,35	N	0,32	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9646	9646	C	G	MI.7560	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	440	147	A	G	gCt/gGt	5,22	1	0	probably_damaging	0,98	neutral	0,33	neutral	2,07	deleterious	-3,18	deleterious	-3,59	low_impact	1,9	damaging	0,55	damaging	0,02	deleterious	3,6	23,2	0,06	0,35	neutral	0,34	disease	0,72	disease	0,53	neutral	0,47	1	neutral	0,98	neutral	0,18	neutral	-2	deleterious	0,75	low_impact	-2,51	medium_impact	0,02	medium_impact	0,52	0,64	0,8	78,16	10,08	N	0,38	N	0,65	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9648	9648	C	G	MI.7561	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	442	148	H	D	Cac/Gac	-7,51	0	0	probably_damaging	0,99	neutral	0,2	neutral	1,45	deleterious	-4,66	deleterious	-8,77	medium_impact	3,4	neutral	0,61	damaging	0,02	deleterious	3,92	23,5	0,04	0,35	neutral	0,35	disease	0,84	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,79	low_impact	-2,81	medium_impact	-0,15	medium_impact	1,86	0,25	0,8	74,33	11,67	N	0,33	N	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9648	9648	C	T	MI.7562	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	442	148	H	Y	Cac/Tac	-7,51	0	0	probably_damaging	0,98	neutral	1	neutral	1,45	deleterious	-4,71	deleterious	-5,85	high_impact	3,63	damaging	0,58	damaging	0,02	deleterious	3,81	23,4	0,12	0,4	neutral	0,38	disease	0,87	disease	0,74	disease	0,7	4	deleterious	0,98	deleterious	0,51	deleterious	2	deleterious	0,8	low_impact	-2,51	high_impact	1,9	high_impact	2,07	0,14	0,8	74,33	11,67	N	0,25	N	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9648	9648	C	A	MI.7563	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	442	148	H	N	Cac/Aac	-7,51	0	0	probably_damaging	0,99	neutral	0,3	neutral	1,44	deleterious	-4,93	deleterious	-6,82	high_impact	4,05	damaging	0,55	damaging	0,02	deleterious	3,99	23,6	0,18	0,45	neutral	0,25	disease	0,82	disease	0,74	disease	0,68	4	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,76	low_impact	-2,81	medium_impact	-0,02	high_impact	2,45	0,28	0,8	74,33	11,67	N	0,29	N	0,96	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9649	9649	A	G	MI.7564	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	443	148	H	R	cAc/cGc	7,3	1	0	probably_damaging	0,98	neutral	0,35	neutral	1,46	deleterious	-4,47	deleterious	-7,8	high_impact	4,05	neutral	0,7	damaging	0,02	deleterious	3,06	22,4	0,06	0,35	neutral	0,29	disease	0,82	disease	0,74	disease	0,69	4	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,8	low_impact	-2,51	medium_impact	0,04	high_impact	2,45	0,27	0,8	74,33	11,67	N	0,5	N	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9649	9649	A	T	MI.7565	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	443	148	H	L	cAc/cTc	7,3	1	0	probably_damaging	0,98	neutral	0,67	neutral	1,44	deleterious	-4,8	deleterious	-10,72	medium_impact	2,96	damaging	0,57	damaging	0,02	deleterious	3,85	23,4	0,03	0,35	neutral	0,13	disease	0,87	disease	0,71	disease	0,69	4	deleterious	0,98	neutral	0,35	deleterious	1	deleterious	0,76	low_impact	-2,51	medium_impact	0,37	medium_impact	1,47	0,08	0,8	74,33	11,67	N	0,33	N	0,96	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9649	9649	A	C	MI.7566	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	443	148	H	P	cAc/cCc	7,3	1	0	probably_damaging	1	neutral	0,2	neutral	1,42	deleterious	-5,91	deleterious	-9,75	high_impact	4,61	damaging	0,59	damaging	0,02	deleterious	3,25	22,8	0,02	0,35	neutral	0,45	disease	0,87	disease	0,83	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,15	high_impact	2,95	0,1	0,8	74,33	11,67	P	0,54	P	0,98	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9650	9650	C	G	MI.7567	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	444	148	H	Q	caC/caG	8,69	1	0,01	probably_damaging	0,99	neutral	0,29	neutral	1,44	deleterious	-4,89	deleterious	-7,8	medium_impact	3,25	neutral	0,63	damaging	0,02	deleterious	3,6	23,2	0,1	0,4	neutral	0,29	disease	0,84	disease	0,67	disease	0,68	4	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,78	low_impact	-2,81	medium_impact	-0,03	medium_impact	1,73	0,33	0,8	74,33	11,67	N	0,38	N	0,94	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9650	9650	C	A	MI.7568	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	444	148	H	Q	caC/caA	8,69	1	0,01	probably_damaging	0,99	neutral	0,29	neutral	1,44	deleterious	-4,89	deleterious	-7,8	medium_impact	3,25	neutral	0,63	damaging	0,02	deleterious	3,95	23,6	0,1	0,4	neutral	0,29	disease	0,84	disease	0,67	disease	0,68	4	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,78	low_impact	-2,81	medium_impact	-0,03	medium_impact	1,73	0,33	0,8	74,33	11,67	N	0,39	N	0,94	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9651	9651	C	A	MI.7569	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	445	149	H	N	Cat/Aat	-3,11	0	0	benign	0,31	neutral	0,32	neutral	2,21	neutral	-0,97	deleterious	-6,82	medium_impact	2,69	damaging	0,52	neutral	0,49	deleterious	4,12	23,8	0,27	0,45	neutral	0,31	disease	0,77	disease	0,53	neutral	0,4	2	neutral	0,61	deleterious	0,51	neutral	-3	deleterious	0,45	medium_impact	-0,53	medium_impact	0,01	medium_impact	1,23	0,27	0,8	74,33	11,21	N	0,36	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8882	8882	C	T	MI.757	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	356	119	S	F	tCt/tTt	0,36	0	0	benign	0	neutral	0,25	neutral	4,31	deleterious	-3,14	neutral	-0,46	neutral_impact	-0,28	neutral	0,96	neutral	0,93	deleterious	0,84	9,69	0,32	0,65	disease	0,85	disease	0,82	neutral	0,26	disease	0,54	1	neutral	0,75	deleterious	0,63	neutral	-6	neutral	0,33	high_impact	2,09	medium_impact	0,02	low_impact	-1,34	0,39	0,9	24,34	26,09	N	0,31	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9651	9651	C	G	MI.7570	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	445	149	H	D	Cat/Gat	-3,11	0	0	benign	0,31	neutral	0,2	neutral	2,2	neutral	-1,51	deleterious	-8,77	high_impact	3,66	neutral	0,64	damaging	0,27	deleterious	3,89	23,5	0,06	0,35	neutral	0,33	disease	0,82	disease	0,67	disease	0,68	4	neutral	0,76	neutral	0,45	neutral	-2	deleterious	0,46	medium_impact	-0,53	medium_impact	-0,15	high_impact	2,1	0,22	0,8	74,33	11,21	N	0,41	N	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9651	9651	C	T	MI.7571	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	445	149	H	Y	Cat/Tat	-3,11	0	0	benign	0	neutral	1	neutral	2,21	neutral	-2,44	deleterious	-5,84	medium_impact	1,99	damaging	0,59	neutral	0,29	deleterious	3,72	23,3	0,16	0,45	neutral	0,25	disease	0,78	neutral	0,33	neutral	0,35	3	neutral	0	deleterious	1	neutral	-3	neutral	0,25	high_impact	2,05	high_impact	1,9	medium_impact	0,6	0,12	0,8	74,33	11,21	N	0,27	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9652	9652	A	G	MI.7572	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	446	149	H	R	cAt/cGt	5,45	1	0	benign	0,12	neutral	0,34	neutral	2,22	neutral	-0,75	deleterious	-7,8	medium_impact	2,69	damaging	0,57	damaging	0,2	deleterious	3,1	22,5	0,1	0,4	neutral	0,2	disease	0,8	disease	0,58	disease	0,65	3	neutral	0,61	deleterious	0,61	neutral	-3	deleterious	0,44	medium_impact	-0,03	medium_impact	0,03	medium_impact	1,23	0,23	0,8	74,33	11,21	N	0,47	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9652	9652	A	T	MI.7573	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	446	149	H	L	cAt/cTt	5,45	1	0	benign	0,04	neutral	0,77	neutral	2,2	neutral	-1,57	deleterious	-10,72	medium_impact	3,04	neutral	0,6	neutral	0,34	deleterious	3,98	23,6	0,05	0,35	neutral	0,23	disease	0,84	disease	0,59	disease	0,61	2	neutral	0,15	deleterious	0,87	neutral	-3	neutral	0,32	medium_impact	0,47	medium_impact	0,49	medium_impact	1,54	0,09	0,8	74,33	11,21	N	0,43	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9652	9652	A	C	MI.7574	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	446	149	H	P	cAt/cCt	5,45	1	0	possibly_damaging	0,64	neutral	0,2	neutral	2,16	neutral	-2,67	deleterious	-9,75	high_impact	4,01	damaging	0,56	damaging	0,26	deleterious	3,31	22,9	0,04	0,35	neutral	0,46	disease	0,88	disease	0,69	disease	0,71	4	neutral	0,82	neutral	0,28	deleterious	1	deleterious	0,72	low_impact	-1,11	medium_impact	-0,15	high_impact	2,41	0,12	0,8	74,33	11,21	P	0,55	P	0,98	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9653	9653	T	G	MI.7575	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	447	149	H	Q	caT/caG	8,69	1	0	benign	0,25	neutral	0,3	neutral	2,21	neutral	-0,71	deleterious	-7,79	medium_impact	3	neutral	0,66	neutral	0,31	deleterious	3,58	23,2	0,13	0,4	neutral	0,21	disease	0,8	disease	0,51	disease	0,51	0	neutral	0,64	deleterious	0,53	neutral	-3	deleterious	0,44	medium_impact	-0,41	medium_impact	-0,02	medium_impact	1,51	0,32	0,8	74,33	11,21	N	0,54	P	0,94	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9653	9653	T	A	MI.7576	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	447	149	H	Q	caT/caA	8,69	1	0	benign	0,25	neutral	0,3	neutral	2,21	neutral	-0,71	deleterious	-7,79	medium_impact	3	neutral	0,66	neutral	0,31	deleterious	3,69	23,3	0,13	0,4	neutral	0,21	disease	0,8	disease	0,51	disease	0,51	0	neutral	0,64	deleterious	0,53	neutral	-3	deleterious	0,44	medium_impact	-0,41	medium_impact	-0,02	medium_impact	1,51	0,32	0,8	74,33	11,21	P	0,53	P	0,94	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9654	9654	A	G	MI.7577	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	448	150	S	G	Agt/Ggt	-5,19	0	0	probably_damaging	0,97	neutral	0,33	neutral	2,49	neutral	-0,98	deleterious	-2,71	low_impact	1,88	neutral	0,62	neutral	0,72	neutral	1,71	14,49	0,14	0,4	neutral	0,35	disease	0,59	neutral	0,23	neutral	0,37	3	neutral	0,98	neutral	0,18	neutral	-2	deleterious	0,72	low_impact	-2,34	medium_impact	0,02	medium_impact	0,5	0,48	0,8	74,71	11,23	N	0,41	N	0,83	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9654	9654	A	C	MI.7578	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	448	150	S	R	Agt/Cgt	-5,19	0	0	probably_damaging	1	neutral	0,34	neutral	2,49	neutral	-0,9	deleterious	-3,98	medium_impact	3,19	neutral	0,64	neutral	0,43	deleterious	3,58	23,2	0,04	0,35	neutral	0,28	disease	0,87	disease	0,63	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,8	low_impact	-3,78	medium_impact	0,03	medium_impact	1,68	0,31	0,8	74,71	11,23	N	0,35	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9654	9654	A	T	MI.7579	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	448	150	S	C	Agt/Tgt	-5,19	0	0	probably_damaging	1	neutral	0,17	neutral	2,47	deleterious	-3,28	deleterious	-3,82	low_impact	1,9	neutral	0,67	neutral	0,42	deleterious	3,22	22,7	0,06	0,35	neutral	0,3	disease	0,82	neutral	0,23	disease	0,59	2	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,74	low_impact	-3,78	medium_impact	-0,2	medium_impact	0,52	0,23	0,8	74,71	11,23	N	0,38	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8882	8882	C	A	MI.758	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	356	119	S	Y	tCt/tAt	0,36	0	0	benign	0,02	neutral	0,33	neutral	4,33	neutral	-1,9	neutral	0,37	neutral_impact	-0,91	neutral	0,93	neutral	0,98	deleterious	0,76	9,23	0,38	0,65	disease	0,66	disease	0,78	neutral	0,23	neutral	0,4	2	neutral	0,65	deleterious	0,66	neutral	-6	neutral	0,29	medium_impact	0,85	medium_impact	0,12	low_impact	-1,88	0,64	0,9	24,34	26,09	N	0,29	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9655	9655	G	T	MI.7580	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	449	150	S	I	aGt/aTt	5,68	1	0	probably_damaging	1	neutral	0,43	neutral	2,5	neutral	-2,06	deleterious	-4,75	medium_impact	3,34	neutral	0,67	neutral	0,59	deleterious	4,08	23,7	0,04	0,35	neutral	0,18	disease	0,92	neutral	0,49	disease	0,73	5	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	0,12	medium_impact	1,81	0,33	0,8	74,71	11,23	P	0,5	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9655	9655	G	A	MI.7581	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	449	150	S	N	aGt/aAt	5,68	1	0	probably_damaging	0,92	neutral	0,38	neutral	2,49	neutral	-1,23	deleterious	-2,72	medium_impact	2,73	neutral	0,69	neutral	0,51	neutral	1,63	14,04	0,49	0,55	neutral	0,3	disease	0,74	neutral	0,26	neutral	0,48	0	neutral	0,92	neutral	0,23	deleterious	1	deleterious	0,73	low_impact	-1,9	medium_impact	0,07	medium_impact	1,26	0,26	0,8	74,71	11,23	P	0,52	P	0,88	polymorphism	1	0,09	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	9655	9655	G	C	MI.7582	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	449	150	S	T	aGt/aCt	5,68	1	0	probably_damaging	0,92	neutral	0,45	neutral	2,5	neutral	-1,09	neutral	-2,25	medium_impact	2,73	neutral	0,68	neutral	0,69	neutral	1,57	13,71	0,23	0,45	neutral	0,18	disease	0,74	neutral	0,47	disease	0,52	0	neutral	0,92	neutral	0,27	deleterious	1	deleterious	0,68	low_impact	-1,9	medium_impact	0,14	medium_impact	1,26	0,5	0,8	74,71	11,23	N	0,51	P	0,63	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9657	9657	C	G	MI.7583	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	451	151	L	V	Cta/Gta	-1,03	0	0	probably_damaging	0,95	neutral	0,62	neutral	2,14	neutral	-1,07	neutral	-1,28	low_impact	1,84	damaging	0,49	damaging	0,08	deleterious	3,46	23	0,22	0,45	neutral	0,2	disease	0,64	neutral	0,21	neutral	0,33	3	neutral	0,95	neutral	0,34	neutral	-2	deleterious	0,69	low_impact	-2,11	medium_impact	0,31	medium_impact	0,47	0,41	0,8	74,71	11,38	N	0,26	N	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9657	9657	C	A	MI.7584	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	451	151	L	M	Cta/Ata	-1,03	0	0	probably_damaging	1	neutral	0,26	neutral	2,04	neutral	-2,24	neutral	-1	low_impact	1,84	damaging	0,55	damaging	0,28	deleterious	2,46	19,2	0,27	0,45	neutral	0,22	neutral	0,49	neutral	0,17	neutral	0,4	2	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,7	low_impact	-3,78	medium_impact	-0,07	medium_impact	0,47	0,48	0,8	74,71	11,38	N	0,48	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9658	9658	T	A	MI.7585	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	452	151	L	Q	cTa/cAa	-1,72	0	0	probably_damaging	1	neutral	0,51	neutral	1,99	deleterious	-3,56	deleterious	-5,01	high_impact	3,66	damaging	0,47	damaging	0,03	deleterious	4,03	23,6	0,02	0,35	disease	0,58	disease	0,87	neutral	0,5	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	0,2	high_impact	2,1	0,18	0,8	74,71	11,38	N	0,26	N	0,97	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9658	9658	T	C	MI.7586	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	452	151	L	P	cTa/cCa	-1,72	0	0	probably_damaging	1	neutral	0,3	neutral	1,98	deleterious	-4,34	deleterious	-5,75	high_impact	4	damaging	0,39	damaging	0,02	deleterious	3,92	23,5	0,01	0,35	disease	0,66	disease	0,91	disease	0,66	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,9	low_impact	-3,78	medium_impact	-0,02	high_impact	2,4	0,15	0,8	74,71	11,38	N	0,38	N	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9658	9658	T	G	MI.7587	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	452	151	L	R	cTa/cGa	-1,72	0	0	probably_damaging	1	neutral	0,54	neutral	1,99	deleterious	-3,5	deleterious	-5,13	high_impact	4	damaging	0,43	damaging	0,03	deleterious	4,16	23,8	0,01	0,35	disease	0,57	disease	0,91	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,89	low_impact	-3,78	medium_impact	0,23	high_impact	2,4	0,14	0,8	74,71	11,38	N	0,3	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9660	9660	A	G	MI.7588	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	454	152	M	V	Ata/Gta	-6,12	0	0	possibly_damaging	0,54	neutral	0,43	neutral	2,4	neutral	0,99	deleterious	-2,65	low_impact	1,75	damaging	0,6	neutral	0,66	neutral	0,96	10,45	0,33	0,5	neutral	0,13	disease	0,65	neutral	0,25	neutral	0,24	5	neutral	0,58	neutral	0,45	neutral	-3	neutral	0,36	medium_impact	-0,94	medium_impact	0,12	medium_impact	0,39	0,29	0,8	75,86	10,9	N	0,36	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9660	9660	A	T	MI.7589	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	454	152	M	L	Ata/Tta	-6,12	0	0	benign	0,42	neutral	0,58	neutral	2,46	neutral	1,44	neutral	-1,64	neutral_impact	0,4	neutral	0,66	neutral	0,74	deleterious	0,43	6,89	0,24	0,45	neutral	0,11	neutral	0,47	neutral	0,17	neutral	0,4	2	neutral	0,39	deleterious	0,58	neutral	-6	neutral	0,28	medium_impact	-0,73	medium_impact	0,27	medium_impact	-0,82	0,31	0,8	75,86	10,9	N	0,46	N	0,95	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8884	8884	A	G	MI.759	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	358	120	K	E	Aag/Gag	-4,96	0	0	probably_damaging	0,99	neutral	0,64	neutral	4,29	neutral	-0,76	neutral	-1,86	low_impact	1,87	neutral	0,91	neutral	0,44	deleterious	4	23,6	0,4	0,65	disease	0,55	disease	0,86	disease	0,63	disease	0,76	5	deleterious	0,99	neutral	0,33	neutral	-2	deleterious	0,85	low_impact	-2,65	medium_impact	0,43	medium_impact	0,51	0,71	0,9	50,44	8,68	N	0,22	N	0,85	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9660	9660	A	C	MI.7590	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	454	152	M	L	Ata/Cta	-6,12	0	0	benign	0,42	neutral	0,58	neutral	2,46	neutral	1,44	neutral	-1,64	neutral_impact	0,4	neutral	0,66	neutral	0,74	deleterious	0,33	5,97	0,24	0,45	neutral	0,11	neutral	0,47	neutral	0,17	neutral	0,4	2	neutral	0,39	deleterious	0,58	neutral	-6	neutral	0,28	medium_impact	-0,73	medium_impact	0,27	medium_impact	-0,82	0,31	0,8	75,86	10,9	N	0,5	N	0,95	polymorphism	1	0,02	.	.	.	.	.	.	.	CPD	0,3	A9660C	LHON	+	-	Reported	1
chrM	9661	9661	T	C	MI.7591	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	455	152	M	T	aTa/aCa	5,68	1	0	possibly_damaging	0,86	neutral	0,69	neutral	2,34	neutral	0,3	deleterious	-4,62	low_impact	1,78	neutral	0,72	neutral	0,74	neutral	1,06	11,01	0,23	0,45	neutral	0,15	disease	0,8	neutral	0,3	neutral	0,25	5	neutral	0,84	neutral	0,42	neutral	-3	deleterious	0,62	low_impact	-1,64	medium_impact	0,39	medium_impact	0,41	0,06	0,8	75,86	10,9	N	0,43	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9661	9661	T	A	MI.7592	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	455	152	M	K	aTa/aAa	5,68	1	0	possibly_damaging	0,74	neutral	0,95	neutral	2,29	neutral	-0,61	deleterious	-4,86	low_impact	0,91	neutral	0,65	neutral	0,4	deleterious	2,44	19,05	0,1	0,4	neutral	0,11	disease	0,87	disease	0,55	disease	0,57	1	neutral	0,71	deleterious	0,61	neutral	-3	deleterious	0,56	low_impact	-1,31	medium_impact	0,92	medium_impact	-0,37	0,15	0,8	75,86	10,9	N	0,39	N	0,99	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9662	9662	A	T	MI.7593	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	456	152	M	I	atA/atT	2,44	1	0	possibly_damaging	0,63	neutral	0,32	neutral	2,46	neutral	1,48	neutral	-2,44	neutral_impact	0,62	neutral	0,65	neutral	0,74	neutral	1,6	13,87	0,29	0,45	neutral	0,11	disease	0,62	neutral	0,16	neutral	0,28	4	neutral	0,72	neutral	0,35	neutral	-3	neutral	0,41	low_impact	-1,09	medium_impact	0,01	medium_impact	-0,63	0,4	0,8	75,86	10,9	P	0,49	N	0,95	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9662	9662	A	C	MI.7594	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	456	152	M	I	atA/atC	2,44	1	0	possibly_damaging	0,63	neutral	0,32	neutral	2,46	neutral	1,48	neutral	-2,44	neutral_impact	0,62	neutral	0,65	neutral	0,74	neutral	1,47	13,15	0,29	0,45	neutral	0,11	disease	0,62	neutral	0,16	neutral	0,28	4	neutral	0,72	neutral	0,35	neutral	-3	neutral	0,41	low_impact	-1,09	medium_impact	0,01	medium_impact	-0,63	0,4	0,8	75,86	10,9	P	0,48	N	0,95	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9663	9663	G	A	MI.7595	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	457	153	E	K	Gaa/Aaa	0,36	0,98	0	benign	0,06	neutral	0,34	neutral	2,28	neutral	0,02	neutral	-2,13	low_impact	0,9	neutral	0,66	neutral	0,54	neutral	1,63	14,01	0,18	0,45	neutral	0,16	disease	0,76	neutral	0,25	neutral	0,25	5	neutral	0,63	deleterious	0,64	neutral	-6	neutral	0,21	medium_impact	0,29	medium_impact	0,03	medium_impact	-0,38	0,43	0,8	26,82	21,02	N	0,45	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9663	9663	G	C	MI.7596	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	457	153	E	Q	Gaa/Caa	0,36	0,98	0	benign	0,12	neutral	0,32	neutral	2,24	neutral	-0,66	neutral	-1,59	low_impact	1,51	neutral	0,73	neutral	0,8	deleterious	0,51	7,52	0,61	0,65	neutral	0,23	disease	0,55	neutral	0,19	neutral	0,24	5	neutral	0,63	deleterious	0,6	neutral	-6	neutral	0,24	medium_impact	-0,03	medium_impact	0,01	medium_impact	0,17	0,44	0,8	26,82	21,02	P	0,6	P	0,83	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9664	9664	A	G	MI.7597	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	458	153	E	G	gAa/gGa	4,29	1	0,01	benign	0,09	neutral	0,35	neutral	2,19	neutral	-2,36	deleterious	-4,44	low_impact	1,86	neutral	0,73	neutral	0,71	deleterious	2,31	18,26	0,29	0,45	neutral	0,36	disease	0,61	neutral	0,41	neutral	0,24	5	neutral	0,61	deleterious	0,63	neutral	-6	neutral	0,24	medium_impact	0,11	medium_impact	0,04	medium_impact	0,48	0,26	0,8	26,82	21,02	P	0,55	P	0,89	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9664	9664	A	T	MI.7598	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	458	153	E	V	gAa/gTa	4,29	1	0,01	benign	0,06	neutral	0,51	neutral	2,22	neutral	-2,27	deleterious	-4,61	medium_impact	2	neutral	0,67	neutral	0,61	deleterious	2,24	17,75	0,21	0,45	neutral	0,29	disease	0,74	neutral	0,37	neutral	0,25	5	neutral	0,43	deleterious	0,73	neutral	-3	neutral	0,21	medium_impact	0,29	medium_impact	0,2	medium_impact	0,61	0,49	0,8	26,82	21,02	N	0,51	P	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9664	9664	A	C	MI.7599	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	458	153	E	A	gAa/gCa	4,29	1	0,01	benign	0,09	neutral	0,54	neutral	2,3	neutral	-0,53	deleterious	-3,41	neutral_impact	0,63	neutral	0,69	neutral	0,76	deleterious	0,56	7,86	0,34	0,5	neutral	0,15	neutral	0,48	neutral	0,25	neutral	0,36	3	neutral	0,38	deleterious	0,73	neutral	-6	neutral	0,17	medium_impact	0,11	medium_impact	0,23	medium_impact	-0,62	0,48	0,8	26,82	21,02	N	0,41	N	0,71	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8560	8560	C	A	MI.76	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	34	12	P	T	Ccc/Acc	0,36	0,11	0	probably_damaging	1	neutral	0,11	neutral	4,66	neutral	0,64	deleterious	-6,86	medium_impact	2,12	neutral	0,62	damaging	0,07	deleterious	3,42	23	0,44	0,65	neutral	0,38	disease	0,77	disease	0,66	disease	0,55	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	-0,22	medium_impact	0,72	0,71	0,9	50	8,94	N	0,3	N	0,93	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8884	8884	A	C	MI.760	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	358	120	K	Q	Aag/Cag	-4,96	0	0	probably_damaging	1	neutral	0,99	neutral	4,28	neutral	-0,89	neutral	-0,83	neutral_impact	-1,02	neutral	0,81	neutral	0,63	deleterious	0,79	9,4	0,6	0,7	neutral	0,34	neutral	0,18	neutral	0,19	neutral	0,28	4	deleterious	0,99	deleterious	0,5	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	1,42	low_impact	-1,97	0,81	0,9	50,44	8,68	N	0,27	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9665	9665	A	T	MI.7600	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	459	153	E	D	gaA/gaT	4,76	1	0	benign	0,02	neutral	0,24	neutral	2,22	neutral	-1,39	neutral	-1,96	medium_impact	2,65	neutral	0,64	neutral	0,6	deleterious	1,91	15,66	0,62	0,65	neutral	0,26	disease	0,58	neutral	0,28	neutral	0,26	5	neutral	0,75	deleterious	0,61	neutral	-3	neutral	0,16	medium_impact	0,77	medium_impact	-0,09	medium_impact	1,19	0,38	0,8	26,82	21,02	P	0,64	P	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9665	9665	A	C	MI.7601	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	459	153	E	D	gaA/gaC	4,76	1	0	benign	0,02	neutral	0,24	neutral	2,22	neutral	-1,39	neutral	-1,96	medium_impact	2,65	neutral	0,64	neutral	0,6	neutral	1,78	14,86	0,62	0,65	neutral	0,26	disease	0,58	neutral	0,28	neutral	0,26	5	neutral	0,75	deleterious	0,61	neutral	-3	neutral	0,16	medium_impact	0,77	medium_impact	-0,09	medium_impact	1,19	0,38	0,8	26,82	21,02	P	0,64	P	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9666	9666	A	T	MI.7602	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	460	154	N	Y	Aac/Tac	0,59	0,98	0	possibly_damaging	0,8	neutral	1	neutral	2,41	deleterious	-3,46	deleterious	-4,17	medium_impact	2,24	neutral	0,68	neutral	0,63	deleterious	3,45	23	0,16	0,45	neutral	0,39	disease	0,79	disease	0,55	disease	0,7	4	neutral	0,8	deleterious	0,6	NA	0	deleterious	0,65	low_impact	-1,45	high_impact	1,9	medium_impact	0,83	0,2	0,8	19,92	56,92	N	0,35	N	0,9	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9666	9666	A	C	MI.7603	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	460	154	N	H	Aac/Cac	0,59	0,98	0	possibly_damaging	0,8	neutral	0,59	neutral	2,43	neutral	-2,39	deleterious	-2,67	low_impact	1,44	neutral	0,73	neutral	0,63	deleterious	2,88	21,8	0,59	0,65	neutral	0,23	disease	0,65	disease	0,56	disease	0,68	4	neutral	0,76	neutral	0,4	neutral	-3	deleterious	0,59	low_impact	-1,45	medium_impact	0,28	medium_impact	0,11	0,17	0,8	19,92	56,92	N	0,36	N	0,43	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9666	9666	A	G	MI.7604	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	460	154	N	D	Aac/Gac	0,59	0,98	0	benign	0,24	neutral	0,32	neutral	2,53	neutral	-0,54	neutral	-2,09	low_impact	1,38	neutral	0,66	neutral	0,68	deleterious	1,98	16,11	0,72	0,75	neutral	0,14	disease	0,63	neutral	0,34	neutral	0,34	3	neutral	0,61	deleterious	0,54	neutral	-6	neutral	0,24	medium_impact	-0,38	medium_impact	0,01	medium_impact	0,05	0,32	0,8	19,92	56,92	N	0,49	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9667	9667	A	G	MI.7605	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	461	154	N	S	aAc/aGc	1,52	0,98	0,01	benign	0,14	neutral	0,57	neutral	2,5	neutral	-0,86	neutral	-0,9	low_impact	0,86	neutral	0,74	neutral	0,81	deleterious	-0,06	2,02	0,74	0,8	neutral	0,13	neutral	0,48	neutral	0,3	neutral	0,41	2	neutral	0,33	deleterious	0,72	neutral	-6	neutral	0,19	medium_impact	-0,1	medium_impact	0,26	medium_impact	-0,41	0,41	0,8	19,92	56,92	N	0,46	N	0,21	polymorphism	1	0,02	rs41482146	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9667	9667	A	C	MI.7606	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	461	154	N	T	aAc/aCc	1,52	0,98	0,01	benign	0,34	neutral	0,49	neutral	2,44	neutral	-1,89	deleterious	-2,55	medium_impact	2,44	neutral	0,65	neutral	0,82	neutral	1,58	13,74	0,45	0,55	neutral	0,17	disease	0,68	disease	0,51	neutral	0,5	0	neutral	0,43	deleterious	0,58	neutral	-3	neutral	0,31	medium_impact	-0,59	medium_impact	0,18	medium_impact	1	0,24	0,8	19,92	56,92	N	0,5	N	0,43	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9667	9667	A	T	MI.7607	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	461	154	N	I	aAc/aTc	1,52	0,98	0,01	possibly_damaging	0,73	neutral	0,42	neutral	2,4	deleterious	-4,86	deleterious	-4,88	medium_impact	3,13	neutral	0,71	neutral	0,67	deleterious	3,58	23,2	0,14	0,4	neutral	0,34	disease	0,85	disease	0,51	disease	0,72	4	neutral	0,73	neutral	0,35	NA	0	deleterious	0,61	low_impact	-1,29	medium_impact	0,11	medium_impact	1,62	0,16	0,8	19,92	56,92	N	0,48	N	0,9	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9668	9668	C	G	MI.7608	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	462	154	N	K	aaC/aaG	1,52	0,95	0	benign	0,34	neutral	0,5	neutral	2,49	neutral	-0,93	deleterious	-2,56	low_impact	1,19	neutral	0,69	neutral	0,72	neutral	0,98	10,52	0,6	0,65	neutral	0,12	disease	0,66	neutral	0,33	neutral	0,33	3	neutral	0,41	deleterious	0,58	neutral	-6	neutral	0,31	medium_impact	-0,59	medium_impact	0,19	medium_impact	-0,12	0,35	0,8	19,92	56,92	N	0,38	N	0,73	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9668	9668	C	A	MI.7609	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	462	154	N	K	aaC/aaA	1,52	0,95	0	benign	0,34	neutral	0,5	neutral	2,49	neutral	-0,93	deleterious	-2,56	low_impact	1,19	neutral	0,69	neutral	0,72	neutral	1,43	12,97	0,6	0,65	neutral	0,12	disease	0,66	neutral	0,33	neutral	0,33	3	neutral	0,41	deleterious	0,58	neutral	-6	neutral	0,31	medium_impact	-0,59	medium_impact	0,19	medium_impact	-0,12	0,35	0,8	19,92	56,92	N	0,38	N	0,73	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8885	8885	A	T	MI.761	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	359	120	K	M	aAg/aTg	3,14	0,99	0	probably_damaging	1	neutral	0,18	neutral	4,16	deleterious	-3,94	deleterious	-3,71	low_impact	1,76	neutral	0,9	neutral	0,57	deleterious	4,03	23,6	0,28	0,65	disease	0,86	disease	0,72	neutral	0,49	disease	0,61	2	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,84	low_impact	-3,6	medium_impact	-0,08	medium_impact	0,41	0,49	0,9	50,44	8,68	N	0,51	P	0,53	polymorphism	0,8	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9669	9669	A	C	MI.7610	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	463	155	N	H	Aac/Cac	-20	0	0	possibly_damaging	0,65	neutral	0,52	neutral	2,34	neutral	-2,85	deleterious	-3,11	medium_impact	2,52	neutral	0,77	neutral	0,95	neutral	1,77	14,83	0,73	0,75	neutral	0,41	disease	0,78	neutral	0,47	neutral	0,33	3	neutral	0,62	neutral	0,44	NA	0	deleterious	0,48	low_impact	-1,13	medium_impact	0,21	medium_impact	1,08	0,15	0,8	18,39	17,31	N	0,31	N	0,39	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9669	9669	A	G	MI.7611	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	463	155	N	D	Aac/Gac	-20	0	0	benign	0,01	neutral	0,54	neutral	2,46	neutral	-0,92	deleterious	-2,61	neutral_impact	0,68	neutral	0,8	neutral	0,99	deleterious	0,49	7,38	0,82	0,85	neutral	0,14	disease	0,54	neutral	0,28	neutral	0,23	5	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,11	medium_impact	1,07	medium_impact	0,23	medium_impact	-0,57	0,28	0,8	18,39	17,31	N	0,35	N	0,01	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9669	9669	A	T	MI.7612	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	463	155	N	Y	Aac/Tac	-20	0	0	possibly_damaging	0,65	neutral	0,58	neutral	2,32	deleterious	-3,83	deleterious	-5,41	medium_impact	2,46	neutral	0,73	neutral	0,54	deleterious	3,39	23	0,19	0,45	disease	0,55	disease	0,87	disease	0,56	disease	0,6	2	neutral	0,6	neutral	0,47	NA	0	deleterious	0,6	low_impact	-1,13	medium_impact	0,27	medium_impact	1,02	0,19	0,8	18,39	17,31	N	0,25	N	0,8	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9670	9670	A	G	MI.7613	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	464	155	N	S	aAc/aGc	-0,33	0	0	benign	0,01	neutral	0,94	neutral	2,42	neutral	-1,33	deleterious	-2,82	medium_impact	2,26	neutral	0,76	neutral	0,95	deleterious	0,6	8,13	0,8	0,85	neutral	0,18	disease	0,69	neutral	0,29	neutral	0,24	5	neutral	0,03	deleterious	0,97	neutral	-3	neutral	0,15	medium_impact	1,07	medium_impact	0,87	medium_impact	0,84	0,33	0,8	18,39	17,31	N	0,3	N	0,01	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9670	9670	A	T	MI.7614	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	464	155	N	I	aAc/aTc	-0,33	0	0	possibly_damaging	0,5	neutral	0,36	neutral	2,31	deleterious	-4,35	deleterious	-6,26	high_impact	3,96	neutral	0,73	neutral	0,53	deleterious	4,23	23,9	0,19	0,45	disease	0,51	disease	0,92	neutral	0,49	disease	0,69	4	neutral	0,61	neutral	0,43	deleterious	1	deleterious	0,47	medium_impact	-0,87	medium_impact	0,05	high_impact	2,37	0,17	0,8	18,39	17,31	N	0,41	N	0,78	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9670	9670	A	C	MI.7615	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	464	155	N	T	aAc/aCc	-0,33	0	0	benign	0,1	neutral	0,6	neutral	2,35	neutral	-2,56	deleterious	-3,77	medium_impact	3,41	neutral	0,71	neutral	0,63	deleterious	2,1	16,86	0,55	0,6	neutral	0,27	disease	0,83	neutral	0,41	disease	0,65	3	neutral	0,31	deleterious	0,75	neutral	-3	neutral	0,2	medium_impact	0,06	medium_impact	0,29	medium_impact	1,87	0,17	0,8	18,39	17,31	N	0,35	N	0,15	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9671	9671	C	A	MI.7616	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	465	155	N	K	aaC/aaA	3,83	0,09	0	benign	0,1	neutral	0,9	neutral	2,42	neutral	-1,33	deleterious	-3,37	low_impact	1,41	neutral	0,68	neutral	0,75	neutral	1,27	12,09	0,67	0,7	neutral	0,13	disease	0,74	neutral	0,31	neutral	0,25	5	neutral	0,04	deleterious	0,9	neutral	-6	neutral	0,19	medium_impact	0,06	medium_impact	0,74	medium_impact	0,08	0,51	0,8	18,39	17,31	N	0,35	N	0,15	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9671	9671	C	G	MI.7617	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	465	155	N	K	aaC/aaG	3,83	0,09	0	benign	0,1	neutral	0,9	neutral	2,42	neutral	-1,33	deleterious	-3,37	low_impact	1,41	neutral	0,68	neutral	0,75	deleterious	0,85	9,79	0,67	0,7	neutral	0,13	disease	0,74	neutral	0,31	neutral	0,25	5	neutral	0,04	deleterious	0,9	neutral	-6	neutral	0,19	medium_impact	0,06	medium_impact	0,74	medium_impact	0,08	0,51	0,8	18,39	17,31	N	0,35	N	0,15	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9672	9672	C	G	MI.7618	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	466	156	R	G	Cga/Gga	-3,57	0	0	probably_damaging	1	neutral	0,54	neutral	2,16	deleterious	-3,14	deleterious	-4	medium_impact	2,25	damaging	0,53	damaging	0,06	deleterious	4,13	23,8	0,08	0,35	neutral	0,32	disease	0,71	disease	0,53	disease	0,56	1	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,72	low_impact	-3,78	medium_impact	0,23	medium_impact	0,83	0,24	0,8	76,25	10,2	N	0,2	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9672	9672	C	T	MI.7619	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	466	156	R	W	Cga/Tga	-3,57	0	0	probably_damaging	1	neutral	0,12	neutral	2,12	deleterious	-6,05	deleterious	-3,69	low_impact	1,8	damaging	0,55	damaging	0,02	deleterious	5,17	25,5	0,09	0,35	disease	0,73	disease	0,84	neutral	0,33	disease	0,55	1	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,3	medium_impact	0,43	0,55	0,8	76,25	10,2	N	0,25	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8885	8885	A	C	MI.762	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	359	120	K	T	aAg/aCg	3,14	0,99	0	probably_damaging	0,99	neutral	0,44	neutral	4,21	neutral	-2,01	deleterious	-3,98	low_impact	1,76	neutral	0,87	neutral	0,51	deleterious	3,74	23,3	0,33	0,65	disease	0,66	disease	0,67	disease	0,59	disease	0,69	4	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,82	low_impact	-2,65	medium_impact	0,23	medium_impact	0,41	0,71	0,9	50,44	8,68	N	0,4	N	0,81	polymorphism	0,9	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9673	9673	G	C	MI.7620	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	467	156	R	P	cGa/cCa	3,6	0,97	0	probably_damaging	1	neutral	0,21	neutral	2,14	deleterious	-3,44	deleterious	-4	medium_impact	2,59	damaging	0,45	damaging	0,02	deleterious	4,23	23,9	0,03	0,35	neutral	0,3	disease	0,92	neutral	0,49	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,79	low_impact	-3,78	medium_impact	-0,14	medium_impact	1,14	0,17	0,8	76,25	10,2	N	0,43	N	0,99	polymorphism	1	0,1	rs28463067	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9673	9673	G	T	MI.7621	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	467	156	R	L	cGa/cTa	3,6	0,97	0	probably_damaging	0,99	neutral	0,6	neutral	2,18	neutral	-2,56	deleterious	-3,54	low_impact	1,37	damaging	0,53	damaging	0,03	deleterious	4,01	23,6	0,11	0,4	neutral	0,24	disease	0,84	neutral	0,44	disease	0,5	0	deleterious	0,99	neutral	0,31	neutral	-2	deleterious	0,73	low_impact	-2,81	medium_impact	0,29	medium_impact	0,05	0,03	0,8	76,25	10,2	N	0,33	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9673	9673	G	A	MI.7622	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	467	156	R	Q	cGa/cAa	3,6	0,97	0	probably_damaging	0,99	neutral	0,41	neutral	2,21	neutral	-1,96	neutral	-1,75	low_impact	1,9	damaging	0,56	damaging	0,06	deleterious	2,57	19,89	0,37	0,5	neutral	0,18	disease	0,72	neutral	0,33	neutral	0,48	0	deleterious	0,99	neutral	0,21	neutral	-2	deleterious	0,69	low_impact	-2,81	medium_impact	0,1	medium_impact	0,52	0,8	0,85	76,25	10,2	N	0,38	N	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9675	9675	A	C	MI.7623	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	469	157	N	H	Aac/Cac	-1,26	0	0	benign	0,34	neutral	0,56	neutral	2,25	neutral	-1,27	neutral	-1,38	low_impact	1,21	neutral	0,7	damaging	0,17	neutral	1,56	13,65	0,66	0,7	neutral	0,34	neutral	0,49	neutral	0,46	disease	0,51	0	neutral	0,36	deleterious	0,61	neutral	-6	neutral	0,23	medium_impact	-0,59	medium_impact	0,25	medium_impact	-0,1	0,15	0,8	16,86	15,28	N	0,24	N	0,37	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9675	9675	A	G	MI.7624	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	469	157	N	D	Aac/Gac	-1,26	0	0	benign	0,03	neutral	0,25	neutral	2,29	neutral	-0,17	neutral	-1,09	low_impact	0,88	neutral	0,65	damaging	0,16	deleterious	2,04	16,45	0,73	0,75	neutral	0,19	neutral	0,48	neutral	0,34	neutral	0,43	1	neutral	0,74	deleterious	0,61	neutral	-6	neutral	0,13	medium_impact	0,6	medium_impact	-0,08	medium_impact	-0,39	0,48	0,8	16,86	15,28	N	0,39	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9675	9675	A	T	MI.7625	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	469	157	N	Y	Aac/Tac	-1,26	0	0	benign	0,19	neutral	1	neutral	2,24	neutral	-1,79	neutral	-2,26	low_impact	0,8	neutral	0,72	neutral	0,82	deleterious	2,07	16,69	0,21	0,45	neutral	0,47	disease	0,61	neutral	0,35	neutral	0,48	0	neutral	0,19	deleterious	0,91	neutral	-6	neutral	0,28	medium_impact	-0,26	high_impact	1,9	medium_impact	-0,47	0,37	0,8	16,86	15,28	N	0,24	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9676	9676	A	G	MI.7626	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	470	157	N	S	aAc/aGc	5,68	0,69	0	benign	0,02	neutral	0,48	neutral	2,33	neutral	0,75	neutral	0,63	neutral_impact	0,02	neutral	0,77	neutral	0,79	neutral	-0,24	0,92	0,71	0,75	neutral	0,13	neutral	0,24	neutral	0,21	neutral	0,42	2	neutral	0,5	deleterious	0,73	neutral	-6	neutral	0,1	medium_impact	0,77	medium_impact	0,17	low_impact	-1,17	0,31	0,8	16,86	15,28	N	0,41	N	0,22	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9676	9676	A	T	MI.7627	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	470	157	N	I	aAc/aTc	5,68	0,69	0	benign	0,05	neutral	0,4	neutral	2,25	neutral	-1,81	deleterious	-2,51	low_impact	1,07	neutral	0,75	neutral	0,46	deleterious	1,92	15,73	0,22	0,45	neutral	0,42	disease	0,71	neutral	0,39	disease	0,53	1	neutral	0,56	deleterious	0,68	neutral	-6	neutral	0,19	medium_impact	0,37	medium_impact	0,09	medium_impact	-0,22	0,33	0,8	16,86	15,28	N	0,39	N	0,76	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9676	9676	A	C	MI.7628	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	470	157	N	T	aAc/aCc	5,68	0,69	0	benign	0	neutral	0,43	neutral	2,3	neutral	0,07	neutral	0,06	neutral_impact	0,24	neutral	0,68	neutral	0,46	deleterious	0,16	4,22	0,53	0,6	neutral	0,22	neutral	0,34	neutral	0,18	neutral	0,44	1	neutral	0,57	deleterious	0,72	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	0,12	medium_impact	-0,97	0,29	0,8	16,86	15,28	N	0,5	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9677	9677	C	A	MI.7629	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	471	157	N	K	aaC/aaA	0,82	0,14	0	benign	0	neutral	0,42	neutral	2,42	neutral	1,51	neutral	1,27	neutral_impact	-1,32	neutral	0,77	neutral	0,95	neutral	-0,16	1,33	0,59	0,65	neutral	0,16	neutral	0,19	neutral	0,19	neutral	0,37	3	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,09	high_impact	2,05	medium_impact	0,11	low_impact	-2,37	0,57	0,8	16,86	15,28	N	0,43	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8886	8886	G	C	MI.763	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	360	120	K	N	aaG/aaC	8,69	1	0	probably_damaging	1	neutral	0,81	neutral	4,25	neutral	-1,29	deleterious	-2,98	neutral_impact	0,2	neutral	0,89	neutral	0,47	deleterious	3,92	23,5	0,6	0,7	neutral	0,44	disease	0,59	neutral	0,31	neutral	0,4	2	deleterious	0,99	neutral	0,41	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,65	medium_impact	-0,93	0,76	0,9	50,44	8,68	N	0,42	N	0,76	disease_causing	0,68	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9677	9677	C	G	MI.7630	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	471	157	N	K	aaC/aaG	0,82	0,14	0	benign	0	neutral	0,42	neutral	2,42	neutral	1,51	neutral	1,27	neutral_impact	-1,32	neutral	0,77	neutral	0,95	neutral	-0,6	0,13	0,59	0,65	neutral	0,16	neutral	0,19	neutral	0,19	neutral	0,37	3	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,09	high_impact	2,05	medium_impact	0,11	low_impact	-2,37	0,57	0,8	16,86	15,28	N	0,43	N	0,07	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9678	9678	C	G	MI.7631	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	472	158	Q	E	Caa/Gaa	-1,03	0	0	benign	0	neutral	0,97	neutral	2,34	neutral	0,19	neutral	0,04	neutral_impact	-0,4	neutral	0,68	neutral	0,52	neutral	-0,96	0,02	0,34	0,5	neutral	0,11	neutral	0,4	neutral	0,17	neutral	0,44	1	neutral	0,02	deleterious	0,99	neutral	-6	neutral	0,14	high_impact	2,05	medium_impact	1,05	low_impact	-1,54	0,43	0,8	22,22	41,6	N	0,38	N	0,35	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9678	9678	C	A	MI.7632	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	472	158	Q	K	Caa/Aaa	-1,03	0	0	benign	0,08	neutral	0,89	neutral	2,34	neutral	0,2	neutral	-1,68	neutral_impact	0,12	neutral	0,66	damaging	0,27	neutral	1,41	12,85	0,25	0,45	neutral	0,13	disease	0,78	neutral	0,31	disease	0,52	0	neutral	0,03	deleterious	0,91	neutral	-6	neutral	0,2	medium_impact	0,16	medium_impact	0,71	low_impact	-1,08	0,43	0,8	22,22	41,6	N	0,22	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9679	9679	A	T	MI.7633	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	473	158	Q	L	cAa/cTa	-0,1	0	0	benign	0,16	neutral	0,79	neutral	2,25	neutral	-1,06	deleterious	-4,88	low_impact	1,39	neutral	0,63	damaging	0,18	deleterious	3,55	23,1	0,13	0,4	neutral	0,28	disease	0,77	neutral	0,33	disease	0,58	2	neutral	0,11	deleterious	0,82	neutral	-6	neutral	0,27	medium_impact	-0,17	medium_impact	0,52	medium_impact	0,06	0,14	0,8	22,22	41,6	N	0,22	N	0,74	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9679	9679	A	C	MI.7634	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	473	158	Q	P	cAa/cCa	-0,1	0	0	benign	0,2	neutral	0,35	neutral	2,22	neutral	-2,1	deleterious	-3,49	low_impact	1,55	neutral	0,74	neutral	0,91	deleterious	2,2	17,48	0,07	0,35	neutral	0,35	disease	0,88	neutral	0,5	disease	0,54	1	neutral	0,58	deleterious	0,58	neutral	-6	neutral	0,4	medium_impact	-0,28	medium_impact	0,04	medium_impact	0,21	0,28	0,8	22,22	41,6	N	0,36	N	0,9	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9679	9679	A	G	MI.7635	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	473	158	Q	R	cAa/cGa	-0,1	0	0	benign	0,08	neutral	0,64	neutral	2,28	neutral	-0,49	neutral	-2,19	low_impact	0,82	neutral	0,61	damaging	0,15	deleterious	3,13	22,6	0,34	0,5	neutral	0,15	disease	0,75	neutral	0,38	disease	0,57	1	neutral	0,27	deleterious	0,78	neutral	-6	neutral	0,23	medium_impact	0,16	medium_impact	0,33	medium_impact	-0,45	0,2	0,8	22,22	41,6	N	0,22	N	0,33	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9680	9680	A	T	MI.7636	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	474	158	Q	H	caA/caT	4,76	0,31	0,01	possibly_damaging	0,57	neutral	0,6	neutral	2,24	neutral	-1,34	neutral	-2,36	low_impact	1,32	neutral	0,74	neutral	0,96	deleterious	2,2	17,51	0,21	0,45	neutral	0,23	disease	0,6	neutral	0,28	neutral	0,45	1	neutral	0,51	deleterious	0,52	neutral	-3	deleterious	0,47	medium_impact	-0,99	medium_impact	0,29	medium_impact	0	0,46	0,8	22,22	41,6	N	0,37	N	0,08	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9680	9680	A	C	MI.7637	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	474	158	Q	H	caA/caC	4,76	0,31	0,01	possibly_damaging	0,57	neutral	0,6	neutral	2,24	neutral	-1,34	neutral	-2,36	low_impact	1,32	neutral	0,74	neutral	0,96	deleterious	2,03	16,41	0,21	0,45	neutral	0,23	disease	0,6	neutral	0,28	neutral	0,45	1	neutral	0,51	deleterious	0,52	neutral	-3	deleterious	0,47	medium_impact	-0,99	medium_impact	0,29	medium_impact	0	0,46	0,8	22,22	41,6	N	0,36	N	0,08	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9681	9681	A	T	MI.7638	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	475	159	M	L	Ata/Tta	-1,72	0	0	benign	0,02	neutral	0,97	neutral	2,69	neutral	1,29	neutral	-0,57	neutral_impact	-0,68	neutral	0,67	neutral	0,5	neutral	1,41	12,83	0,26	0,45	neutral	0,1	neutral	0,49	neutral	0,41	neutral	0,42	2	neutral	0	deleterious	0,98	neutral	-6	neutral	0,16	medium_impact	0,77	medium_impact	1,05	low_impact	-1,79	0,4	0,8	22,22	41,39	N	0,3	N	0,68	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9681	9681	A	G	MI.7639	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	475	159	M	V	Ata/Gta	-1,72	0	0	benign	0,02	neutral	0,67	neutral	2,69	neutral	0,6	neutral	-0,02	neutral_impact	0	neutral	0,8	neutral	0,73	deleterious	0,74	9,06	0,26	0,45	neutral	0,1	neutral	0,49	neutral	0,37	neutral	0,42	2	neutral	0,29	deleterious	0,83	neutral	-6	neutral	0,16	medium_impact	0,77	medium_impact	0,37	low_impact	-1,18	0,42	0,8	22,22	41,39	N	0,21	N	0,87	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8886	8886	G	T	MI.764	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	360	120	K	N	aaG/aaT	8,69	1	0	probably_damaging	1	neutral	0,81	neutral	4,25	neutral	-1,29	deleterious	-2,98	neutral_impact	0,2	neutral	0,89	neutral	0,47	deleterious	4,05	23,7	0,6	0,7	neutral	0,44	disease	0,59	neutral	0,31	neutral	0,4	2	deleterious	0,99	neutral	0,41	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,65	medium_impact	-0,93	0,76	0,9	50,44	8,68	N	0,43	N	0,76	disease_causing	0,68	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9681	9681	A	C	MI.7640	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	475	159	M	L	Ata/Cta	-1,72	0	0	benign	0,02	neutral	0,97	neutral	2,69	neutral	1,29	neutral	-0,57	neutral_impact	-0,68	neutral	0,67	neutral	0,5	neutral	1,31	12,31	0,26	0,45	neutral	0,1	neutral	0,49	neutral	0,41	neutral	0,42	2	neutral	0	deleterious	0,98	neutral	-6	neutral	0,16	medium_impact	0,77	medium_impact	1,05	low_impact	-1,79	0,4	0,8	22,22	41,39	N	0,3	N	0,68	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9682	9682	T	C	MI.7641	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	476	159	M	T	aTa/aCa	1,52	0,21	0	benign	0	neutral	0,65	neutral	2,65	neutral	0,29	neutral	1,17	neutral_impact	-0,94	neutral	0,78	neutral	0,8	neutral	-0,42	0,36	0,13	0,4	neutral	0,19	neutral	0,34	neutral	0,34	neutral	0,43	1	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,14	high_impact	2,05	medium_impact	0,35	low_impact	-2,03	0,17	0,8	22,22	41,39	N	0,23	N	0,51	polymorphism	1	0	rs199750417	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9682	9682	T	A	MI.7642	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	476	159	M	K	aTa/aAa	1,52	0,21	0	benign	0,05	neutral	0,47	neutral	2,56	neutral	-2,13	neutral	-0,88	low_impact	1,25	damaging	0,58	neutral	0,41	deleterious	2,34	18,45	0,03	0,35	neutral	0,3	disease	0,8	neutral	0,48	disease	0,66	3	neutral	0,48	deleterious	0,71	neutral	-6	neutral	0,26	medium_impact	0,37	medium_impact	0,16	medium_impact	-0,06	0,21	0,8	22,22	41,39	N	0,34	N	0,95	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9683	9683	A	C	MI.7643	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	477	159	M	I	atA/atC	2,21	0,22	0	benign	0,05	neutral	0,52	neutral	2,6	neutral	-0,26	neutral	-0,71	low_impact	1,02	neutral	0,67	neutral	0,56	neutral	1,64	14,09	0,21	0,45	neutral	0,16	disease	0,59	neutral	0,35	neutral	0,48	0	neutral	0,43	deleterious	0,74	neutral	-6	neutral	0,2	medium_impact	0,37	medium_impact	0,21	medium_impact	-0,27	0,4	0,8	22,22	41,39	N	0,36	N	0,8	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9683	9683	A	T	MI.7644	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	477	159	M	I	atA/atT	2,21	0,22	0	benign	0,05	neutral	0,52	neutral	2,6	neutral	-0,26	neutral	-0,71	low_impact	1,02	neutral	0,67	neutral	0,56	neutral	1,7	14,42	0,21	0,45	neutral	0,16	disease	0,59	neutral	0,35	neutral	0,48	0	neutral	0,43	deleterious	0,74	neutral	-6	neutral	0,2	medium_impact	0,37	medium_impact	0,21	medium_impact	-0,27	0,4	0,8	22,22	41,39	N	0,36	N	0,8	disease_causing	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9684	9684	A	T	MI.7645	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	478	160	I	F	Att/Ttt	-1,03	0	0	benign	0,28	neutral	0,64	neutral	2,19	neutral	-1,47	neutral	-2,02	low_impact	1,22	neutral	0,68	neutral	0,59	deleterious	3,38	22,9	0,21	0,45	neutral	0,32	disease	0,64	neutral	0,42	neutral	0,48	0	neutral	0,26	deleterious	0,68	neutral	-6	neutral	0,38	medium_impact	-0,47	medium_impact	0,33	medium_impact	-0,09	0,54	0,8	26,05	51,21	N	0,28	N	0,64	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9684	9684	A	G	MI.7646	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	478	160	I	V	Att/Gtt	-1,03	0	0	benign	0,03	neutral	0,55	neutral	2,31	neutral	-0,1	neutral	-0,19	low_impact	1,28	neutral	0,71	neutral	0,73	deleterious	0,09	3,5	0,55	0,6	neutral	0,12	neutral	0,23	neutral	0,28	neutral	0,41	2	neutral	0,41	deleterious	0,76	neutral	-6	neutral	0,1	medium_impact	0,6	medium_impact	0,24	medium_impact	-0,04	0,59	0,8	26,05	51,21	N	0,34	N	0,69	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9684	9684	A	C	MI.7647	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	478	160	I	L	Att/Ctt	-1,03	0	0	benign	0,03	neutral	1	neutral	2,38	neutral	0,37	neutral	-0,62	neutral_impact	0,15	neutral	0,78	neutral	0,94	deleterious	0,39	6,52	0,26	0,45	neutral	0,12	neutral	0,38	neutral	0,22	neutral	0,43	1	neutral	0,03	deleterious	0,99	neutral	-6	neutral	0,1	medium_impact	0,6	high_impact	1,9	low_impact	-1,05	0,52	0,8	26,05	51,21	N	0,29	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9685	9685	T	G	MI.7648	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	479	160	I	S	aTt/aGt	0,13	0	0	benign	0,05	neutral	0,81	neutral	2,18	neutral	-1,64	neutral	-1,92	low_impact	1,54	neutral	0,71	neutral	0,75	deleterious	2,42	18,96	0,08	0,35	neutral	0,29	disease	0,69	neutral	0,43	disease	0,51	0	neutral	0,11	deleterious	0,88	neutral	-6	neutral	0,18	medium_impact	0,37	medium_impact	0,55	medium_impact	0,2	0,15	0,8	26,05	51,21	N	0,32	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9685	9685	T	A	MI.7649	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	479	160	I	N	aTt/aAt	0,13	0	0	benign	0	neutral	0,42	neutral	2,15	neutral	-2,61	deleterious	-2,73	low_impact	1,47	neutral	0,72	neutral	0,72	neutral	1,54	13,54	0,21	0,45	neutral	0,38	disease	0,71	neutral	0,32	disease	0,51	0	neutral	0,58	deleterious	0,71	neutral	-6	neutral	0,19	high_impact	2,05	medium_impact	0,11	medium_impact	0,14	0,16	0,8	26,05	51,21	N	0,38	N	0,2	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8887	8887	A	T	MI.765	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	361	121	I	F	Att/Ttt	0,36	0,13	0,01	benign	0	neutral	0,54	neutral	4,43	neutral	-0,55	neutral	-1,08	neutral_impact	-0,9	neutral	0,9	neutral	0,64	neutral	1,53	13,5	0,47	0,65	disease	0,62	disease	0,58	neutral	0,36	neutral	0,42	2	neutral	0,46	deleterious	0,77	neutral	-6	neutral	0,23	high_impact	2,09	medium_impact	0,33	low_impact	-1,87	0,64	0,9	23,01	21,88	N	0,28	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9685	9685	T	C	MI.7650	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	479	160	I	T	aTt/aCt	0,13	0	0	benign	0	neutral	0,9	neutral	2,22	neutral	-1,06	neutral	-0,96	low_impact	1	neutral	0,7	neutral	0,75	neutral	-0,07	1,95	0,23	0,45	neutral	0,22	neutral	0,41	neutral	0,33	neutral	0,44	1	neutral	0,09	deleterious	0,95	neutral	-6	neutral	0,12	high_impact	2,05	medium_impact	0,74	medium_impact	-0,29	0,26	0,8	26,05	51,21	N	0,35	N	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9686	9686	T	G	MI.7651	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	480	160	I	M	atT/atG	1,05	0	0	possibly_damaging	0,47	neutral	0,24	neutral	2,17	neutral	-1,87	neutral	-0,94	low_impact	1,73	neutral	0,78	neutral	0,75	deleterious	2,22	17,65	0,47	0,55	neutral	0,26	neutral	0,46	neutral	0,3	neutral	0,47	1	neutral	0,73	neutral	0,39	neutral	-3	neutral	0,36	medium_impact	-0,82	medium_impact	-0,09	medium_impact	0,37	0,64	0,8	26,05	51,21	N	0,42	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9686	9686	T	A	MI.7652	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	480	160	I	M	atT/atA	1,05	0	0	possibly_damaging	0,47	neutral	0,24	neutral	2,17	neutral	-1,87	neutral	-0,94	low_impact	1,73	neutral	0,78	neutral	0,75	deleterious	2,45	19,18	0,47	0,55	neutral	0,26	neutral	0,46	neutral	0,3	neutral	0,47	1	neutral	0,73	neutral	0,39	neutral	-3	neutral	0,36	medium_impact	-0,82	medium_impact	-0,09	medium_impact	0,37	0,64	0,8	26,05	51,21	N	0,43	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9687	9687	C	A	MI.7653	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	481	161	Q	K	Caa/Aaa	-6,58	0	0	possibly_damaging	0,86	neutral	0,32	neutral	2,58	neutral	-0,17	neutral	-2,33	low_impact	1,55	damaging	0,5	damaging	0,06	deleterious	3,91	23,5	0,25	0,45	neutral	0,11	disease	0,84	neutral	0,32	neutral	0,5	0	neutral	0,88	neutral	0,23	neutral	-3	deleterious	0,6	low_impact	-1,64	medium_impact	0,01	medium_impact	0,21	0,38	0,8	75,1	11,31	N	0,28	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9687	9687	C	G	MI.7654	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	481	161	Q	E	Caa/Gaa	-6,58	0	0	possibly_damaging	0,72	neutral	0,29	neutral	2,55	neutral	-0,76	neutral	-2,01	medium_impact	2	damaging	0,51	damaging	0,04	deleterious	3,16	22,6	0,42	0,55	neutral	0,15	disease	0,81	neutral	0,4	disease	0,63	3	neutral	0,79	neutral	0,29	NA	0	deleterious	0,6	low_impact	-1,27	medium_impact	-0,03	medium_impact	0,61	0,5	0,8	75,1	11,31	N	0,26	N	0,95	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9688	9688	A	T	MI.7655	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	482	161	Q	L	cAa/cTa	7,3	1	0	possibly_damaging	0,86	neutral	0,75	neutral	2,72	neutral	1,49	deleterious	-4,08	neutral_impact	0,6	damaging	0,5	damaging	0,06	deleterious	3,8	23,4	0,12	0,4	neutral	0,15	disease	0,82	neutral	0,28	neutral	0,47	1	neutral	0,83	neutral	0,45	neutral	-3	deleterious	0,65	low_impact	-1,64	medium_impact	0,46	medium_impact	-0,65	0,12	0,8	75,1	11,31	N	0,42	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9688	9688	A	G	MI.7656	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	482	161	Q	R	cAa/cGa	7,3	1	0	possibly_damaging	0,9	neutral	0,35	neutral	2,6	neutral	0,27	neutral	-2,5	low_impact	1,6	damaging	0,5	damaging	0,06	deleterious	3,47	23	0,25	0,45	neutral	0,2	disease	0,84	neutral	0,36	disease	0,52	0	neutral	0,91	neutral	0,23	neutral	-3	deleterious	0,69	low_impact	-1,8	medium_impact	0,04	medium_impact	0,25	0,11	0,8	75,1	11,31	P	0,47	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9688	9688	A	C	MI.7657	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	482	161	Q	P	cAa/cCa	7,3	1	0	probably_damaging	0,96	neutral	0,2	neutral	2,54	neutral	-1,34	deleterious	-4,13	high_impact	3,5	damaging	0,46	damaging	0,02	deleterious	3,38	22,9	0,06	0,35	neutral	0,37	disease	0,94	disease	0,55	disease	0,76	5	neutral	0,97	neutral	0,12	deleterious	2	deleterious	0,8	low_impact	-2,21	medium_impact	-0,15	medium_impact	1,95	0,32	0,8	75,1	11,31	N	0,49	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9689	9689	A	C	MI.7658	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	483	161	Q	H	caA/caC	8,69	1	0	probably_damaging	0,97	neutral	0,56	neutral	2,54	neutral	-1,17	deleterious	-3,03	medium_impact	2	damaging	0,57	neutral	0,3	deleterious	2,28	18,01	0,32	0,5	neutral	0,3	disease	0,72	neutral	0,3	neutral	0,49	0	neutral	0,97	neutral	0,3	deleterious	1	deleterious	0,74	low_impact	-2,34	medium_impact	0,25	medium_impact	0,61	0,43	0,8	75,1	11,31	N	0,44	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9689	9689	A	T	MI.7659	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	483	161	Q	H	caA/caT	8,69	1	0	probably_damaging	0,97	neutral	0,56	neutral	2,54	neutral	-1,17	deleterious	-3,03	medium_impact	2	damaging	0,57	neutral	0,3	deleterious	2,41	18,91	0,32	0,5	neutral	0,3	disease	0,72	neutral	0,3	neutral	0,49	0	neutral	0,97	neutral	0,3	deleterious	1	deleterious	0,74	low_impact	-2,34	medium_impact	0,25	medium_impact	0,61	0,43	0,8	75,1	11,31	N	0,44	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8887	8887	A	G	MI.766	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	361	121	I	V	Att/Gtt	0,36	0,13	0,01	benign	0	neutral	0,24	neutral	4,41	neutral	0,63	neutral	0,64	neutral_impact	0,14	neutral	0,93	neutral	0,62	neutral	0,94	10,33	0,67	0,75	neutral	0,43	neutral	0,31	neutral	0,5	neutral	0,46	1	neutral	0,76	deleterious	0,62	neutral	-6	neutral	0,13	high_impact	2,09	medium_impact	0,01	medium_impact	-0,98	0,63	0,9	23,01	21,88	N	0,36	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9690	9690	G	C	MI.7660	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	484	162	A	P	Gca/Cca	0,13	0,96	0	probably_damaging	1	neutral	0,24	neutral	2,5	neutral	-2,93	deleterious	-3,33	medium_impact	2,64	damaging	0,46	damaging	0,03	deleterious	3,89	23,5	0,04	0,35	neutral	0,46	disease	0,92	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,85	low_impact	-3,78	medium_impact	-0,09	medium_impact	1,18	0,52	0,8	72,03	11,53	N	0,36	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9690	9690	G	T	MI.7661	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	484	162	A	S	Gca/Tca	0,13	0,96	0	probably_damaging	0,99	neutral	0,61	neutral	2,57	neutral	-0,68	neutral	-0,62	neutral_impact	-0,07	neutral	0,61	neutral	0,36	neutral	1,54	13,55	0,3	0,45	neutral	0,17	neutral	0,26	neutral	0,25	neutral	0,44	1	deleterious	0,99	neutral	0,31	neutral	-2	deleterious	0,68	low_impact	-2,81	medium_impact	0,3	low_impact	-1,25	0,41	0,8	72,03	11,53	N	0,35	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9690	9690	G	A	MI.7662	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	484	162	A	T	Gca/Aca	0,13	0,96	0	probably_damaging	0,99	neutral	0,53	neutral	2,52	neutral	-0,95	neutral	-2,34	medium_impact	2,09	damaging	0,48	damaging	0,03	deleterious	4,3	24	0,21	0,45	neutral	0,25	disease	0,66	disease	0,57	disease	0,63	3	deleterious	0,99	neutral	0,27	deleterious	1	deleterious	0,72	low_impact	-2,81	medium_impact	0,22	medium_impact	0,69	0,72	0,85	72,03	11,53	N	0,35	N	0,86	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9691	9691	C	G	MI.7663	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	485	162	A	G	gCa/gGa	2,9	1	0	probably_damaging	0,98	neutral	0,49	neutral	2,59	neutral	0,34	neutral	-0,75	neutral_impact	-0,22	damaging	0,56	damaging	0,17	deleterious	2,32	18,33	0,25	0,45	neutral	0,23	neutral	0,16	neutral	0,26	neutral	0,24	5	neutral	0,97	neutral	0,26	neutral	-2	deleterious	0,66	low_impact	-2,51	medium_impact	0,18	low_impact	-1,38	0,44	0,8	72,03	11,53	N	0,45	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9691	9691	C	A	MI.7664	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	485	162	A	E	gCa/gAa	2,9	1	0	probably_damaging	1	neutral	0,42	neutral	2,5	neutral	-2,1	deleterious	-3,07	medium_impact	3,34	damaging	0,5	damaging	0,03	deleterious	4,51	24,3	0,03	0,35	neutral	0,27	disease	0,89	disease	0,7	disease	0,78	6	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,79	low_impact	-3,78	medium_impact	0,11	medium_impact	1,81	0,31	0,8	72,03	11,53	N	0,4	N	0,97	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9691	9691	C	T	MI.7665	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	485	162	A	V	gCa/gTa	2,9	1	0	probably_damaging	0,99	neutral	0,61	neutral	2,55	neutral	-0,37	deleterious	-3,36	medium_impact	2,79	damaging	0,46	damaging	0,04	deleterious	4,42	24,2	0,21	0,45	neutral	0,21	disease	0,71	disease	0,58	disease	0,69	4	deleterious	0,99	neutral	0,31	deleterious	1	deleterious	0,73	low_impact	-2,81	medium_impact	0,3	medium_impact	1,32	0,68	0,85	72,03	11,53	N	0,45	N	0,87	polymorphism	1	0,12	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	9693	9693	C	A	MI.7666	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	487	163	L	M	Ctg/Atg	-9,59	0	0	probably_damaging	1	neutral	0,2	neutral	1,97	neutral	-2,43	neutral	-1,89	medium_impact	2,54	damaging	0,49	damaging	0,08	deleterious	3,83	23,4	0,17	0,45	neutral	0,32	disease	0,58	neutral	0,44	neutral	0,43	1	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	-0,15	medium_impact	1,09	0,47	0,8	75,48	11,49	N	0,31	N	0,85	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9693	9693	C	G	MI.7667	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	487	163	L	V	Ctg/Gtg	-9,59	0	0	probably_damaging	0,95	neutral	0,31	neutral	1,98	neutral	-2,51	deleterious	-2,75	high_impact	3,8	damaging	0,52	damaging	0,01	deleterious	3,47	23	0,15	0,4	neutral	0,22	disease	0,72	disease	0,65	disease	0,66	3	neutral	0,96	neutral	0,18	deleterious	2	deleterious	0,72	low_impact	-2,11	medium_impact	-0,01	high_impact	2,22	0,61	0,8	75,48	11,49	N	0,28	N	0,81	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9694	9694	T	G	MI.7668	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	488	163	L	R	cTg/cGg	-0,33	0	0	probably_damaging	1	neutral	0,11	neutral	1,93	deleterious	-4,88	deleterious	-5,75	high_impact	4,6	neutral	0,68	damaging	0,02	deleterious	4,19	23,8	0,02	0,35	disease	0,56	disease	0,93	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,88	low_impact	-3,78	medium_impact	-0,33	high_impact	2,94	0,18	0,8	75,48	11,49	N	0,46	N	0,99	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9694	9694	T	C	MI.7669	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	488	163	L	P	cTg/cCg	-0,33	0	0	probably_damaging	1	neutral	0,07	neutral	1,91	deleterious	-5,27	deleterious	-6,68	high_impact	4,05	damaging	0,59	damaging	0,03	deleterious	3,96	23,6	0,02	0,35	disease	0,65	disease	0,9	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,88	low_impact	-3,78	medium_impact	-0,45	high_impact	2,45	0,37	0,8	75,48	11,49	N	0,33	N	0,99	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8887	8887	A	C	MI.767	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	361	121	I	L	Att/Ctt	0,36	0,13	0,01	benign	0	neutral	0,34	neutral	4,41	neutral	0,27	neutral	0,1	neutral_impact	-0,46	neutral	0,93	neutral	0,88	deleterious	0,44	6,92	0,57	0,65	neutral	0,28	neutral	0,37	neutral	0,46	neutral	0,45	1	neutral	0,66	deleterious	0,67	neutral	-6	neutral	0,14	high_impact	2,09	medium_impact	0,13	low_impact	-1,49	0,63	0,9	23,01	21,88	N	0,41	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9694	9694	T	A	MI.7670	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	488	163	L	Q	cTg/cAg	-0,33	0	0	probably_damaging	1	neutral	0,25	neutral	1,92	deleterious	-4,55	deleterious	-5,75	high_impact	4,25	neutral	0,62	damaging	0,02	deleterious	4,25	23,9	0,03	0,35	disease	0,58	disease	0,87	disease	0,66	disease	0,73	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	-0,08	high_impact	2,63	0,28	0,8	75,48	11,49	N	0,34	N	0,97	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9696	9696	C	G	MI.7671	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	490	164	L	V	Ctt/Gtt	-4,5	0	0	benign	0,06	neutral	0,33	neutral	2,29	neutral	-0,23	neutral	-0,44	neutral_impact	0,79	neutral	0,76	neutral	0,85	neutral	-0,29	0,71	0,36	0,5	neutral	0,12	neutral	0,27	neutral	0,21	neutral	0,41	2	neutral	0,64	deleterious	0,64	neutral	-6	neutral	0,14	medium_impact	0,29	medium_impact	0,02	medium_impact	-0,48	0,61	0,8	22,99	31,12	N	0,42	N	0,35	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9696	9696	C	T	MI.7672	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	490	164	L	F	Ctt/Ttt	-4,5	0	0	benign	0	neutral	0,47	neutral	2,22	neutral	-0,79	neutral	-0,21	neutral_impact	0,6	neutral	0,78	neutral	0,98	neutral	-0,37	0,46	0,27	0,45	neutral	0,21	neutral	0,2	neutral	0,21	neutral	0,37	3	neutral	0,53	deleterious	0,74	neutral	-6	neutral	0,13	high_impact	2,05	medium_impact	0,16	medium_impact	-0,65	0,53	0,8	22,99	31,12	N	0,43	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9696	9696	C	A	MI.7673	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	490	164	L	I	Ctt/Att	-4,5	0	0	benign	0,06	neutral	0,38	neutral	2,28	neutral	-0,28	neutral	-0,24	neutral_impact	0,34	neutral	0,8	neutral	0,86	deleterious	0,54	7,72	0,34	0,5	neutral	0,14	neutral	0,18	neutral	0,17	neutral	0,31	4	neutral	0,58	deleterious	0,66	neutral	-6	neutral	0,14	medium_impact	0,29	medium_impact	0,07	medium_impact	-0,88	0,52	0,8	22,99	31,12	N	0,47	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9697	9697	T	A	MI.7674	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	491	164	L	H	cTt/cAt	-3,11	0	0	possibly_damaging	0,62	neutral	0,35	neutral	2,09	deleterious	-3,69	deleterious	-2,51	medium_impact	3,36	neutral	0,75	neutral	0,51	deleterious	2,02	16,33	0,05	0,35	disease	0,51	disease	0,61	neutral	0,44	neutral	0,46	1	neutral	0,69	neutral	0,37	NA	0	deleterious	0,58	low_impact	-1,08	medium_impact	0,04	medium_impact	1,83	0,21	0,8	22,99	31,12	N	0,37	N	0,7	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9697	9697	T	G	MI.7675	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	491	164	L	R	cTt/cGt	-3,11	0	0	benign	0,3	neutral	0,18	neutral	2,1	deleterious	-3,05	neutral	-2,38	medium_impact	3,02	neutral	0,64	neutral	0,48	deleterious	2,19	17,43	0,02	0,35	neutral	0,42	disease	0,8	neutral	0,5	disease	0,65	3	neutral	0,79	neutral	0,44	neutral	-3	deleterious	0,45	medium_impact	-0,51	medium_impact	-0,18	medium_impact	1,52	0,26	0,8	22,99	31,12	N	0,39	N	0,82	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9697	9697	T	C	MI.7676	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	491	164	L	P	cTt/cCt	-3,11	0	0	possibly_damaging	0,45	neutral	0,11	neutral	2,09	deleterious	-3,73	deleterious	-2,82	medium_impact	3,02	damaging	0,56	neutral	0,35	deleterious	2,27	17,98	0,02	0,35	disease	0,52	disease	0,84	disease	0,53	disease	0,74	5	neutral	0,88	neutral	0,33	NA	0	deleterious	0,57	medium_impact	-0,78	medium_impact	-0,33	medium_impact	1,52	0,22	0,8	22,99	31,12	N	0,35	N	0,9	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9699	9699	A	G	MI.7677	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	493	165	I	V	Att/Gtt	-14,22	0	0	benign	0,01	neutral	0,29	neutral	2,33	neutral	0,08	neutral	-0,67	neutral_impact	0,42	neutral	0,78	neutral	0,75	neutral	1,18	11,66	0,4	0,5	neutral	0,13	neutral	0,31	neutral	0,31	neutral	0,44	1	neutral	0,7	deleterious	0,64	neutral	-6	neutral	0,09	medium_impact	1,07	medium_impact	-0,03	medium_impact	-0,81	0,31	0,8	20,69	32,67	N	0,36	N	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9699	9699	A	C	MI.7678	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	493	165	I	L	Att/Ctt	-14,22	0	0	benign	0,04	neutral	1	neutral	2,51	neutral	1	neutral	0,36	neutral_impact	-0,57	neutral	0,73	neutral	0,83	neutral	-0,72	0,06	0,26	0,45	neutral	0,13	neutral	0,22	neutral	0,22	neutral	0,41	2	neutral	0,04	deleterious	0,98	neutral	-6	neutral	0,1	medium_impact	0,47	high_impact	1,9	low_impact	-1,69	0,39	0,8	20,69	32,67	N	0,32	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9699	9699	A	T	MI.7679	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	493	165	I	F	Att/Ttt	-14,22	0	0	benign	0,41	neutral	0,6	neutral	2,2	neutral	-1,24	neutral	-1,35	neutral_impact	0,7	neutral	0,71	neutral	0,75	deleterious	2,29	18,09	0,19	0,45	neutral	0,2	disease	0,54	neutral	0,31	neutral	0,45	1	neutral	0,37	deleterious	0,6	neutral	-6	neutral	0,4	medium_impact	-0,72	medium_impact	0,29	medium_impact	-0,56	0,46	0,8	20,69	32,67	N	0,32	N	0,94	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8888	8888	T	A	MI.768	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	362	121	I	N	aTt/aAt	1,05	0,13	0	benign	0	neutral	0,14	neutral	4,42	neutral	-1,69	neutral	-0,14	neutral_impact	0,06	neutral	0,88	neutral	0,52	deleterious	2,49	19,38	0,58	0,7	disease	0,55	disease	0,76	disease	0,64	disease	0,67	3	neutral	0,86	deleterious	0,57	neutral	-6	neutral	0,25	high_impact	2,09	medium_impact	-0,15	low_impact	-1,05	0,45	0,9	23,01	21,88	N	0,35	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9700	9700	T	C	MI.7680	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	494	165	I	T	aTt/aCt	0,36	0,01	0	benign	0,01	neutral	0,48	neutral	2,17	neutral	-1,8	deleterious	-2,89	medium_impact	1,97	neutral	0,7	neutral	0,69	deleterious	0,31	5,81	0,13	0,4	neutral	0,19	disease	0,54	disease	0,51	neutral	0,49	0	neutral	0,51	deleterious	0,74	neutral	-3	neutral	0,12	medium_impact	1,07	medium_impact	0,17	medium_impact	0,58	0,26	0,8	20,69	32,67	N	0,42	N	0,91	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9700	9700	T	A	MI.7681	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	494	165	I	N	aTt/aAt	0,36	0,01	0	benign	0,37	neutral	0,13	neutral	2,13	deleterious	-3,25	deleterious	-4,57	medium_impact	2,87	neutral	0,67	neutral	0,29	deleterious	4,04	23,7	0,1	0,4	disease	0,5	disease	0,81	disease	0,53	disease	0,74	5	neutral	0,85	neutral	0,38	neutral	-3	deleterious	0,56	medium_impact	-0,64	medium_impact	-0,28	medium_impact	1,39	0,34	0,8	20,69	32,67	N	0,34	N	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9700	9700	T	G	MI.7682	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	494	165	I	S	aTt/aGt	0,36	0,01	0	benign	0,17	neutral	0,12	neutral	2,16	neutral	-2,21	deleterious	-3,52	medium_impact	2,32	neutral	0,66	neutral	0,39	deleterious	2,67	20,6	0,04	0,35	neutral	0,32	disease	0,73	neutral	0,43	disease	0,52	0	neutral	0,86	deleterious	0,48	neutral	-3	neutral	0,3	medium_impact	-0,2	medium_impact	-0,3	medium_impact	0,9	0,25	0,8	20,69	32,67	N	0,44	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9701	9701	T	G	MI.7683	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	495	165	I	M	atT/atG	3,83	0,4	0,01	possibly_damaging	0,61	neutral	0,11	neutral	2,2	neutral	-1,34	neutral	-0,13	neutral_impact	0,77	neutral	0,72	neutral	0,73	deleterious	1,99	16,16	0,29	0,45	neutral	0,28	neutral	0,43	neutral	0,3	neutral	0,46	1	neutral	0,89	neutral	0,25	neutral	-3	deleterious	0,44	low_impact	-1,06	medium_impact	-0,33	medium_impact	-0,49	0,5	0,8	20,69	32,67	N	0,46	N	0,66	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9701	9701	T	A	MI.7684	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	495	165	I	M	atT/atA	3,83	0,4	0,01	possibly_damaging	0,61	neutral	0,11	neutral	2,2	neutral	-1,34	neutral	-0,13	neutral_impact	0,77	neutral	0,72	neutral	0,73	deleterious	2,28	18,06	0,29	0,45	neutral	0,28	neutral	0,43	neutral	0,3	neutral	0,46	1	neutral	0,89	neutral	0,25	neutral	-3	deleterious	0,44	low_impact	-1,06	medium_impact	-0,33	medium_impact	-0,49	0,5	0,8	20,69	32,67	N	0,46	N	0,66	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9702	9702	A	G	MI.7685	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	496	166	T	A	Aca/Gca	-6,35	0	0	probably_damaging	0,95	neutral	0,52	neutral	1,98	deleterious	-3,1	deleterious	-4,82	medium_impact	3,44	neutral	0,66	damaging	0,03	deleterious	3,51	23,1	0,1	0,4	neutral	0,45	disease	0,65	disease	0,68	neutral	0,49	0	neutral	0,95	neutral	0,29	deleterious	1	deleterious	0,72	low_impact	-2,11	medium_impact	0,21	medium_impact	1,9	0,28	0,8	74,33	11,51	N	0,25	N	0,44	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9702	9702	A	T	MI.7686	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	496	166	T	S	Aca/Tca	-6,35	0	0	probably_damaging	0,95	neutral	0,41	neutral	1,95	deleterious	-3,56	deleterious	-3,86	medium_impact	2,65	neutral	0,66	damaging	0,03	deleterious	3,3	22,9	0,14	0,4	disease	0,52	disease	0,72	disease	0,67	disease	0,6	2	neutral	0,95	neutral	0,23	deleterious	1	deleterious	0,74	low_impact	-2,11	medium_impact	0,1	medium_impact	1,19	0,53	0,8	74,33	11,51	N	0,21	N	0,77	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9702	9702	A	C	MI.7687	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	496	166	T	P	Aca/Cca	-6,35	0	0	probably_damaging	0,99	neutral	0,2	neutral	1,84	deleterious	-6,01	deleterious	-5,78	high_impact	4,73	neutral	0,68	damaging	0,05	deleterious	3,51	23,1	0,03	0,35	disease	0,76	disease	0,88	disease	0,8	disease	0,8	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-2,81	medium_impact	-0,15	high_impact	3,06	0,34	0,8	74,33	11,51	P	0,61	P	0,98	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9703	9703	C	T	MI.7688	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	497	166	T	M	aCa/aTa	8,69	1	0	probably_damaging	1	neutral	0,24	neutral	1,84	deleterious	-5,39	deleterious	-5,78	high_impact	4,73	neutral	0,69	damaging	0,01	deleterious	4,02	23,6	0,04	0,35	disease	0,7	disease	0,87	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,09	high_impact	3,06	0,45	0,8	74,33	11,51	P	0,69	P	0,96	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9703	9703	C	A	MI.7689	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	497	166	T	K	aCa/aAa	8,69	1	0	probably_damaging	0,99	neutral	0,28	neutral	1,84	deleterious	-4,75	deleterious	-5,78	high_impact	4,73	neutral	0,72	damaging	0,02	deleterious	4,43	24,2	0,05	0,35	disease	0,65	disease	0,92	disease	0,79	disease	0,81	6	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-2,81	medium_impact	-0,04	high_impact	3,06	0,33	0,8	74,33	11,51	P	0,73	P	0,99	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8888	8888	T	C	MI.769	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	362	121	I	T	aTt/aCt	1,05	0,13	0	benign	0	neutral	0,71	neutral	4,47	neutral	-1,01	neutral	2,42	neutral_impact	-1,76	neutral	0,92	neutral	0,97	neutral	-0,48	0,24	0,58	0,7	neutral	0,29	neutral	0,16	neutral	0,37	neutral	0,29	4	neutral	0,29	deleterious	0,86	neutral	-6	neutral	0,13	high_impact	2,09	medium_impact	0,51	low_impact	-2,61	0,37	0,9	23,01	21,88	N	0,29	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9705	9705	A	G	MI.7690	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	499	167	I	V	Att/Gtt	-20	0	0	possibly_damaging	0,87	neutral	0,43	neutral	2,24	neutral	-0,36	neutral	0,14	neutral_impact	0,07	neutral	0,69	neutral	0,78	neutral	-0,54	0,18	0,41	0,5	neutral	0,14	neutral	0,09	neutral	0,28	neutral	0,25	5	neutral	0,86	neutral	0,28	neutral	-3	deleterious	0,44	low_impact	-1,67	medium_impact	0,12	low_impact	-1,12	0,42	0,8	74,33	11,42	N	0,41	N	0,62	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9705	9705	A	C	MI.7691	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	499	167	I	L	Att/Ctt	-20	0	0	probably_damaging	0,95	neutral	1	neutral	2,09	neutral	-1,23	neutral	-1,75	low_impact	1,77	neutral	0,62	neutral	0,69	deleterious	3,51	23,1	0,24	0,45	neutral	0,15	disease	0,7	neutral	0,32	neutral	0,5	0	neutral	0,95	deleterious	0,53	neutral	-2	deleterious	0,5	low_impact	-2,11	high_impact	1,9	medium_impact	0,4	0,48	0,8	74,33	11,42	N	0,28	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9705	9705	A	T	MI.7692	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	499	167	I	F	Att/Ttt	-20	0	0	probably_damaging	0,99	neutral	0,78	neutral	1,95	neutral	-2,95	deleterious	-3,6	medium_impact	2,33	neutral	0,61	neutral	0,45	deleterious	4,03	23,7	0,17	0,45	neutral	0,25	disease	0,81	disease	0,6	disease	0,66	3	deleterious	0,99	neutral	0,4	deleterious	1	deleterious	0,71	low_impact	-2,81	medium_impact	0,51	medium_impact	0,91	0,5	0,8	74,33	11,42	N	0,27	N	0,94	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9706	9706	T	G	MI.7693	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	500	167	I	S	aTt/aGt	2,21	0,95	0	probably_damaging	1	neutral	0,34	neutral	1,93	deleterious	-3,58	deleterious	-4,66	medium_impact	3,42	neutral	0,64	neutral	0,44	deleterious	4,27	23,9	0,04	0,35	neutral	0,47	disease	0,82	disease	0,57	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,75	low_impact	-3,78	medium_impact	0,03	medium_impact	1,88	0,29	0,8	74,33	11,42	N	0,44	N	0,93	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9706	9706	T	A	MI.7694	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	500	167	I	N	aTt/aAt	2,21	0,95	0	probably_damaging	1	neutral	0,19	neutral	1,9	deleterious	-4,67	deleterious	-5,71	high_impact	3,98	damaging	0,6	neutral	0,38	deleterious	4,65	24,5	0,09	0,35	disease	0,65	disease	0,87	disease	0,59	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,17	high_impact	2,38	0,3	0,8	74,33	11,42	N	0,49	N	0,97	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9706	9706	T	C	MI.7695	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	500	167	I	T	aTt/aCt	2,21	0,95	0	probably_damaging	1	neutral	0,85	neutral	1,94	deleterious	-3,03	deleterious	-3,21	medium_impact	2,69	neutral	0,67	neutral	0,55	neutral	1,69	14,34	0,1	0,4	neutral	0,33	disease	0,63	disease	0,56	neutral	0,49	0	deleterious	1	neutral	0,43	deleterious	1	deleterious	0,69	low_impact	-3,78	medium_impact	0,62	medium_impact	1,23	0,35	0,8	74,33	11,42	N	0,36	N	0,91	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9707	9707	T	A	MI.7696	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	501	167	I	M	atT/atA	7,53	0,99	0	probably_damaging	1	neutral	0,18	neutral	1,94	deleterious	-3,19	neutral	-2,17	medium_impact	2,27	neutral	0,61	neutral	0,48	deleterious	3,84	23,4	0,28	0,45	neutral	0,43	disease	0,7	disease	0,59	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,71	low_impact	-3,78	medium_impact	-0,18	medium_impact	0,85	0,58	0,8	74,33	11,42	P	0,52	P	0,66	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9707	9707	T	G	MI.7697	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	501	167	I	M	atT/atG	7,53	0,99	0	probably_damaging	1	neutral	0,18	neutral	1,94	deleterious	-3,19	neutral	-2,17	medium_impact	2,27	neutral	0,61	neutral	0,48	deleterious	3,47	23	0,28	0,45	neutral	0,43	disease	0,7	disease	0,59	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,71	low_impact	-3,78	medium_impact	-0,18	medium_impact	0,85	0,58	0,8	74,33	11,42	P	0,52	P	0,66	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9708	9708	T	G	MI.7698	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	502	168	L	V	Tta/Gta	-8,2	0	0	probably_damaging	0,98	neutral	0,56	neutral	2,41	neutral	-0,94	neutral	-0,31	neutral_impact	0,6	neutral	0,79	neutral	0,85	deleterious	1,93	15,76	0,29	0,45	neutral	0,19	neutral	0,27	neutral	0,23	neutral	0,44	1	deleterious	0,98	neutral	0,29	neutral	-2	deleterious	0,63	low_impact	-2,51	medium_impact	0,25	medium_impact	-0,65	0,42	0,8	9,96	29,93	N	0,28	N	0,31	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9708	9708	T	A	MI.7699	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	502	168	L	M	Tta/Ata	-8,2	0	0	probably_damaging	1	neutral	0,12	neutral	2,29	deleterious	-3	neutral	-0,54	low_impact	1,39	neutral	0,81	neutral	0,94	deleterious	2,34	18,45	0,25	0,45	neutral	0,38	neutral	0,27	neutral	0,24	neutral	0,46	1	deleterious	1	neutral	0,06	neutral	-2	deleterious	0,65	low_impact	-3,78	medium_impact	-0,3	medium_impact	0,06	0,35	0,8	9,96	29,93	N	0,45	N	0,09	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8560	8560	C	T	MI.77	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	34	12	P	S	Ccc/Tcc	0,36	0,11	0	probably_damaging	1	neutral	0,73	neutral	4,74	neutral	0,74	deleterious	-6,74	medium_impact	2,21	neutral	0,61	damaging	0,08	deleterious	3,66	23,2	0,54	0,65	neutral	0,29	disease	0,75	disease	0,52	disease	0,52	0	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,54	medium_impact	0,8	0,26	0,9	50	8,94	N	0,21	N	0,79	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8888	8888	T	G	MI.770	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	362	121	I	S	aTt/aGt	1,05	0,13	0	benign	0	neutral	0,28	neutral	4,44	neutral	-1,41	neutral	0,9	neutral_impact	-0,34	neutral	0,83	neutral	0,53	deleterious	2,35	18,49	0,49	0,65	neutral	0,45	disease	0,63	neutral	0,46	neutral	0,42	2	neutral	0,72	deleterious	0,64	neutral	-6	neutral	0,2	high_impact	2,09	medium_impact	0,06	low_impact	-1,39	0,4	0,9	23,01	21,88	N	0,33	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9709	9709	T	C	MI.7700	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	503	168	L	S	tTa/tCa	-5,89	0	0	probably_damaging	0,99	neutral	0,19	neutral	2,3	deleterious	-3,17	deleterious	-3,12	low_impact	1,41	neutral	0,8	neutral	0,93	deleterious	0,75	9,15	0,07	0,35	neutral	0,26	neutral	0,46	neutral	0,4	neutral	0,46	1	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,65	low_impact	-2,81	medium_impact	-0,17	medium_impact	0,08	0,28	0,8	9,96	29,93	N	0,37	N	0,12	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9709	9709	T	G	MI.7701	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	503	168	L	W	tTa/tGa	-5,89	0	0	probably_damaging	1	neutral	0,08	neutral	2,26	deleterious	-4,99	deleterious	-4,05	medium_impact	2,73	neutral	0,65	neutral	0,36	deleterious	3,68	23,3	0,07	0,35	disease	0,53	disease	0,72	disease	0,51	disease	0,55	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	-0,41	medium_impact	1,26	0,21	0,8	9,96	29,93	N	0,3	N	0,59	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9710	9710	A	C	MI.7702	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	504	168	L	F	ttA/ttC	-0,57	0	0	probably_damaging	0,99	neutral	0,44	neutral	2,33	neutral	-2,61	neutral	-2,15	low_impact	0,98	neutral	0,8	neutral	0,83	deleterious	2,34	18,43	0,25	0,45	neutral	0,39	neutral	0,43	neutral	0,26	neutral	0,47	1	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,68	low_impact	-2,81	medium_impact	0,13	medium_impact	-0,3	0,42	0,8	9,96	29,93	N	0,32	N	0,36	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9710	9710	A	T	MI.7703	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	504	168	L	F	ttA/ttT	-0,57	0	0	probably_damaging	0,99	neutral	0,44	neutral	2,33	neutral	-2,61	neutral	-2,15	low_impact	0,98	neutral	0,8	neutral	0,83	deleterious	2,45	19,14	0,25	0,45	neutral	0,39	neutral	0,43	neutral	0,26	neutral	0,47	1	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,68	low_impact	-2,81	medium_impact	0,13	medium_impact	-0,3	0,42	0,8	9,96	29,93	N	0,32	N	0,36	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9711	9711	C	A	MI.7704	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	505	169	L	M	Ctg/Atg	-6,12	0	0,01	probably_damaging	1	neutral	0,21	neutral	1,68	deleterious	-3,88	neutral	-1,6	medium_impact	2,45	damaging	0,53	damaging	0,04	deleterious	3,8	23,4	0,2	0,45	neutral	0,35	disease	0,67	disease	0,55	disease	0,56	1	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,72	low_impact	-3,78	medium_impact	-0,14	medium_impact	1,01	0,46	0,8	73,18	11,49	N	0,26	N	0,85	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9711	9711	C	G	MI.7705	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	505	169	L	V	Ctg/Gtg	-6,12	0	0,01	probably_damaging	0,98	neutral	0,61	neutral	1,78	neutral	-2,41	deleterious	-2,72	high_impact	4,7	damaging	0,52	damaging	0,03	deleterious	3,49	23,1	0,18	0,45	neutral	0,3	disease	0,66	disease	0,65	disease	0,67	3	neutral	0,97	neutral	0,32	deleterious	2	deleterious	0,73	low_impact	-2,51	medium_impact	0,3	high_impact	3,03	0,39	0,8	73,18	11,49	N	0,45	N	0,81	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9712	9712	T	G	MI.7706	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	506	169	L	R	cTg/cGg	-1,03	0	0	probably_damaging	1	neutral	0,24	neutral	1,65	deleterious	-4,99	deleterious	-5,58	high_impact	4,7	neutral	0,66	damaging	0,02	deleterious	4,21	23,9	0,04	0,35	disease	0,63	disease	0,92	disease	0,76	disease	0,8	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	-0,09	high_impact	3,03	0,15	0,8	73,18	11,49	P	0,56	P	0,99	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9712	9712	T	C	MI.7707	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	506	169	L	P	cTg/cCg	-1,03	0	0	probably_damaging	1	neutral	0,14	neutral	1,64	deleterious	-5,69	deleterious	-6,53	high_impact	4,34	damaging	0,57	damaging	0,03	deleterious	3,99	23,6	0,04	0,35	disease	0,72	disease	0,86	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	-0,26	high_impact	2,71	0,25	0,8	73,18	11,49	N	0,37	N	0,99	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9712	9712	T	A	MI.7708	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	506	169	L	Q	cTg/cAg	-1,03	0	0	probably_damaging	1	neutral	0,25	neutral	1,65	deleterious	-5,14	deleterious	-5,51	high_impact	4,7	neutral	0,62	damaging	0,02	deleterious	4,23	23,9	0,05	0,35	disease	0,65	disease	0,83	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,08	high_impact	3,03	0,25	0,8	73,18	11,49	N	0,51	P	0,97	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9714	9714	G	A	MI.7709	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	508	170	G	S	Ggt/Agt	-0,33	0,22	0	probably_damaging	1	neutral	0,37	neutral	1,31	deleterious	-4,63	deleterious	-5,79	medium_impact	3,42	damaging	0,56	damaging	0,01	deleterious	4,2	23,9	0,06	0,35	neutral	0,32	disease	0,8	disease	0,62	disease	0,62	2	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,75	low_impact	-3,78	medium_impact	0,06	medium_impact	1,88	0,55	0,8	73,95	11,77	N	0,27	N	0,85	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8889	8889	T	A	MI.771	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	363	121	I	M	atT/atA	1,75	0,12	0	benign	0	neutral	0,09	neutral	4,38	neutral	-1,34	neutral	0,46	neutral_impact	-0,16	neutral	0,93	neutral	0,89	deleterious	0,64	8,4	0,73	0,75	disease	0,61	neutral	0,38	neutral	0,48	disease	0,61	2	neutral	0,91	deleterious	0,55	neutral	-6	neutral	0,18	high_impact	2,09	medium_impact	-0,28	low_impact	-1,24	0,78	0,9	23,01	21,88	N	0,44	N	0,04	polymorphism	1	0,01	rs386829058	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9714	9714	G	C	MI.7710	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	508	170	G	R	Ggt/Cgt	-0,33	0,22	0	probably_damaging	1	neutral	0,31	neutral	1,23	deleterious	-7,98	deleterious	-7,71	high_impact	4,7	neutral	0,63	damaging	0,02	deleterious	3,95	23,6	0,03	0,35	disease	0,63	disease	0,92	disease	0,76	disease	0,82	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	-0,01	high_impact	3,03	0,32	0,8	73,95	11,77	N	0,51	P	0,99	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9714	9714	G	T	MI.7711	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	508	170	G	C	Ggt/Tgt	-0,33	0,22	0	probably_damaging	1	neutral	0,16	neutral	1,24	deleterious	-7,45	deleterious	-8,68	high_impact	4,7	damaging	0,55	damaging	0,01	deleterious	4,19	23,8	0,04	0,35	disease	0,73	disease	0,9	disease	0,65	disease	0,72	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	-0,22	high_impact	3,03	0,14	0,8	73,95	11,77	N	0,46	N	0,98	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9715	9715	G	A	MI.7712	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	509	170	G	D	gGt/gAt	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	1,23	deleterious	-7,6	deleterious	-6,75	high_impact	4,7	damaging	0,5	damaging	0,01	deleterious	3,81	23,4	0,03	0,35	disease	0,64	disease	0,91	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,18	high_impact	3,03	0,15	0,8	73,95	11,77	P	0,56	P	0,98	polymorphism	1	0,49	.	.	.	.	.	.	COSM1155706	.	.	.	.	.	.	.	.
chrM	9715	9715	G	T	MI.7713	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	509	170	G	V	gGt/gTt	7,3	1	0	probably_damaging	1	neutral	0,58	neutral	1,24	deleterious	-6,78	deleterious	-8,68	high_impact	4,36	damaging	0,53	damaging	0,01	deleterious	3,89	23,5	0,03	0,35	disease	0,52	disease	0,87	disease	0,67	disease	0,74	5	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	0,27	high_impact	2,73	0,12	0,8	73,95	11,77	N	0,45	N	0,97	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9715	9715	G	C	MI.7714	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	509	170	G	A	gGt/gCt	7,3	1	0	probably_damaging	1	neutral	0,45	neutral	1,55	neutral	-2,65	deleterious	-5,79	medium_impact	2,4	damaging	0,45	damaging	0,02	deleterious	3,19	22,7	0,07	0,35	neutral	0,15	neutral	0,48	neutral	0,39	neutral	0,4	2	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,7	low_impact	-3,78	medium_impact	0,14	medium_impact	0,97	0,24	0,8	73,95	11,77	N	0,44	N	0,3	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9717	9717	C	A	MI.7715	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	511	171	L	I	Ctc/Atc	-14,22	0	0	benign	0	neutral	0,37	neutral	2,29	neutral	-0,97	neutral	0,36	neutral_impact	0,42	neutral	0,8	neutral	0,98	deleterious	0,21	4,77	0,36	0,5	neutral	0,2	neutral	0,09	neutral	0,17	neutral	0,3	4	neutral	0,63	deleterious	0,69	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	0,06	medium_impact	-0,81	0,55	0,8	18,39	27,73	N	0,55	P	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9717	9717	C	T	MI.7716	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	511	171	L	F	Ctc/Ttc	-14,22	0	0	benign	0,08	neutral	0,97	neutral	2,18	neutral	-1,86	neutral	-2,03	low_impact	1,09	neutral	0,7	neutral	0,85	deleterious	0,49	7,39	0,2	0,45	neutral	0,27	neutral	0,34	neutral	0,27	neutral	0,45	1	neutral	0,03	deleterious	0,95	neutral	-6	neutral	0,15	medium_impact	0,16	medium_impact	1,05	medium_impact	-0,21	0,45	0,8	18,39	27,73	N	0,35	N	0,41	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9717	9717	C	G	MI.7717	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	511	171	L	V	Ctc/Gtc	-14,22	0	0	benign	0	neutral	0,59	neutral	2,32	neutral	-0,44	neutral	0,02	neutral_impact	0,26	neutral	0,83	neutral	0,98	neutral	-0,25	0,85	0,34	0,5	neutral	0,14	neutral	0,14	neutral	0,2	neutral	0,28	4	neutral	0,41	deleterious	0,8	neutral	-6	neutral	0,09	high_impact	2,05	medium_impact	0,28	medium_impact	-0,95	0,58	0,8	18,39	27,73	N	0,4	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9718	9718	T	C	MI.7718	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	512	171	L	P	cTc/cCc	-5,66	0	0	benign	0,15	neutral	0,17	neutral	2,11	deleterious	-4,11	deleterious	-4,34	medium_impact	2,79	damaging	0,55	neutral	0,3	deleterious	2,09	16,76	0,03	0,35	disease	0,55	disease	0,86	disease	0,63	disease	0,76	5	neutral	0,8	deleterious	0,51	neutral	-3	neutral	0,32	medium_impact	-0,14	medium_impact	-0,2	medium_impact	1,32	0,22	0,8	18,39	27,73	N	0,31	N	0,76	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9718	9718	T	A	MI.7719	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	512	171	L	H	cTc/cAc	-5,66	0	0	possibly_damaging	0,53	neutral	0,45	neutral	2,11	deleterious	-4,18	deleterious	-4,49	high_impact	3,59	neutral	0,68	neutral	0,46	deleterious	3,79	23,4	0,05	0,35	disease	0,54	disease	0,65	disease	0,58	disease	0,69	4	neutral	0,56	neutral	0,46	deleterious	1	neutral	0,42	medium_impact	-0,92	medium_impact	0,14	high_impact	2,04	0,19	0,8	18,39	27,73	N	0,32	N	0,55	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8889	8889	T	G	MI.772	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	363	121	I	M	atT/atG	1,75	0,12	0	benign	0	neutral	0,09	neutral	4,38	neutral	-1,34	neutral	0,46	neutral_impact	-0,16	neutral	0,93	neutral	0,89	deleterious	0,4	6,64	0,73	0,75	disease	0,61	neutral	0,38	neutral	0,48	disease	0,61	2	neutral	0,91	deleterious	0,55	neutral	-6	neutral	0,18	high_impact	2,09	medium_impact	-0,28	low_impact	-1,24	0,78	0,9	23,01	21,88	N	0,44	N	0,04	polymorphism	1	0,01	rs386829058	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9718	9718	T	G	MI.7720	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	512	171	L	R	cTc/cGc	-5,66	0	0	benign	0,15	neutral	0,29	neutral	2,12	deleterious	-3,61	deleterious	-4,13	high_impact	3,59	neutral	0,61	neutral	0,39	deleterious	2,39	18,74	0,02	0,35	neutral	0,44	disease	0,83	disease	0,63	disease	0,75	5	neutral	0,66	deleterious	0,57	neutral	-2	neutral	0,3	medium_impact	-0,14	medium_impact	-0,03	high_impact	2,04	0,17	0,8	18,39	27,73	N	0,39	N	0,62	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9720	9720	T	C	MI.7721	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	514	172	Y	H	Tat/Cat	-11,44	0	0	probably_damaging	1	neutral	0,16	neutral	2,19	neutral	-2,87	deleterious	-4,68	high_impact	4,16	damaging	0,57	damaging	0,03	neutral	1,71	14,44	0,22	0,45	neutral	0,43	disease	0,84	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,77	low_impact	-3,78	medium_impact	-0,22	high_impact	2,55	0,24	0,8	73,95	11,67	N	0,33	N	0,97	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9720	9720	T	G	MI.7722	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	514	172	Y	D	Tat/Gat	-11,44	0	0	probably_damaging	1	neutral	0,06	neutral	2,19	neutral	-2,96	deleterious	-9,3	high_impact	4,16	neutral	0,63	damaging	0,02	deleterious	3,92	23,5	0,08	0,35	neutral	0,5	disease	0,91	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	-0,49	high_impact	2,55	0,23	0,8	73,95	11,67	N	0,39	N	0,99	disease_causing	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9720	9720	T	A	MI.7723	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	514	172	Y	N	Tat/Aat	-11,44	0	0	probably_damaging	1	neutral	0,09	neutral	2,2	neutral	-2,42	deleterious	-8,37	high_impact	3,82	damaging	0,6	damaging	0,02	deleterious	3,96	23,6	0,15	0,45	neutral	0,38	disease	0,87	disease	0,61	disease	0,71	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,75	low_impact	-3,78	medium_impact	-0,38	high_impact	2,24	0,26	0,8	73,95	11,67	N	0,35	N	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9721	9721	A	C	MI.7724	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	515	172	Y	S	tAt/tCt	7,53	1	0	probably_damaging	0,99	neutral	0,11	neutral	2,23	neutral	-1,42	deleterious	-8,31	medium_impact	2,88	neutral	0,61	damaging	0,04	deleterious	3,74	23,3	0,12	0,4	neutral	0,23	disease	0,82	disease	0,59	disease	0,64	3	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,74	low_impact	-2,81	medium_impact	-0,33	medium_impact	1,4	0,29	0,8	73,95	11,67	N	0,41	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9721	9721	A	T	MI.7725	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	515	172	Y	F	tAt/tTt	7,53	1	0	probably_damaging	0,96	neutral	0,71	neutral	2,23	neutral	-1,3	deleterious	-3,64	medium_impact	2,31	damaging	0,53	damaging	0,05	deleterious	3,44	23	0,28	0,45	neutral	0,24	disease	0,76	neutral	0,41	disease	0,51	0	neutral	0,96	neutral	0,38	deleterious	1	deleterious	0,71	low_impact	-2,21	medium_impact	0,41	medium_impact	0,89	0,41	0,8	73,95	11,67	N	0,42	N	0,72	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9721	9721	A	G	MI.7726	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	515	172	Y	C	tAt/tGt	7,53	1	0	probably_damaging	1	neutral	0,12	neutral	2,19	neutral	-2,88	deleterious	-8,29	medium_impact	2,53	neutral	0,61	damaging	0,03	deleterious	3,61	23,2	0,1	0,4	neutral	0,24	disease	0,88	disease	0,58	disease	0,66	3	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,72	low_impact	-3,78	medium_impact	-0,3	medium_impact	1,09	0,07	0,8	73,95	11,67	N	0,37	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9723	9723	T	G	MI.7727	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	517	173	F	V	Ttt/Gtt	-3,11	0	0	probably_damaging	1	neutral	0,33	neutral	0,63	deleterious	-7,79	deleterious	-6,75	high_impact	4,8	neutral	0,66	damaging	0,02	deleterious	4,22	23,9	0,04	0,35	disease	0,67	disease	0,87	disease	0,75	disease	0,78	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	0,02	high_impact	3,12	0,16	0,8	73,95	11,66	P	0,6	P	0,97	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9723	9723	T	C	MI.7728	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	517	173	F	L	Ttt/Ctt	-3,11	0	0	probably_damaging	0,98	neutral	0,52	neutral	0,66	deleterious	-6,34	deleterious	-5,78	high_impact	4,45	neutral	0,64	damaging	0,03	deleterious	4,25	23,9	0,04	0,35	disease	0,56	disease	0,87	disease	0,7	disease	0,73	5	deleterious	0,98	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-2,51	medium_impact	0,21	high_impact	2,81	0,39	0,8	73,95	11,66	N	0,37	N	0,92	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9723	9723	T	A	MI.7729	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	517	173	F	I	Ttt/Att	-3,11	0	0	probably_damaging	0,99	neutral	0,24	neutral	0,63	deleterious	-7,6	deleterious	-5,78	high_impact	4,8	neutral	0,69	damaging	0,02	deleterious	4,73	24,6	0,06	0,35	disease	0,69	disease	0,83	disease	0,74	disease	0,76	5	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,81	low_impact	-2,81	medium_impact	-0,09	high_impact	3,12	0,24	0,8	73,95	11,66	P	0,61	P	0,96	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8890	8890	A	C	MI.773	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	364	122	K	Q	Aaa/Caa	-20	0	0	probably_damaging	1	neutral	0,51	neutral	4,38	neutral	-0,26	neutral	-2,26	low_impact	1,26	neutral	0,87	damaging	0,18	deleterious	3,46	23	0,48	0,65	disease	0,61	neutral	0,49	neutral	0,34	disease	0,52	0	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,78	low_impact	-3,6	medium_impact	0,3	medium_impact	-0,02	0,66	0,9	47,35	8,39	N	0,25	N	0,86	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9724	9724	T	C	MI.7730	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	518	173	F	S	tTt/tCt	7,3	1	0	probably_damaging	1	neutral	0,14	neutral	0,62	deleterious	-8,52	deleterious	-7,71	high_impact	4,45	damaging	0,56	damaging	0,02	deleterious	4,29	24	0,02	0,35	disease	0,61	disease	0,85	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	-0,26	high_impact	2,81	0,13	0,8	73,95	11,66	N	0,46	N	0,96	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9724	9724	T	G	MI.7731	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	518	173	F	C	tTt/tGt	7,3	1	0	probably_damaging	1	neutral	0,09	neutral	0,62	deleterious	-9,7	deleterious	-7,71	high_impact	4,8	neutral	0,72	damaging	0,02	deleterious	4,16	23,8	0,02	0,35	disease	0,89	disease	0,86	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,38	high_impact	3,12	0,09	0,8	73,95	11,66	P	0,59	P	0,98	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9724	9724	T	A	MI.7732	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	518	173	F	Y	tTt/tAt	7,3	1	0	probably_damaging	0,98	neutral	0,73	neutral	0,79	deleterious	-4,49	deleterious	-2,89	high_impact	4,45	neutral	0,71	damaging	0,03	deleterious	4,25	23,9	0,09	0,4	neutral	0,45	disease	0,8	disease	0,7	disease	0,7	4	deleterious	0,98	neutral	0,38	deleterious	2	deleterious	0,78	low_impact	-2,51	medium_impact	0,44	high_impact	2,81	0,36	0,8	73,95	11,66	N	0,53	P	0,8	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9725	9725	T	G	MI.7733	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	519	173	F	L	ttT/ttG	7,3	1	0	probably_damaging	0,98	neutral	0,52	neutral	0,66	deleterious	-6,34	deleterious	-5,78	high_impact	4,45	neutral	0,64	damaging	0,03	deleterious	4,3	24	0,04	0,35	disease	0,56	disease	0,87	disease	0,7	disease	0,73	5	deleterious	0,98	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-2,51	medium_impact	0,21	high_impact	2,81	0,39	0,8	73,95	11,66	N	0,53	P	0,92	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9725	9725	T	A	MI.7734	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	519	173	F	L	ttT/ttA	7,3	1	0	probably_damaging	0,98	neutral	0,52	neutral	0,66	deleterious	-6,34	deleterious	-5,78	high_impact	4,45	neutral	0,64	damaging	0,03	deleterious	4,44	24,2	0,04	0,35	disease	0,56	disease	0,87	disease	0,7	disease	0,73	5	deleterious	0,98	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-2,51	medium_impact	0,21	high_impact	2,81	0,39	0,8	73,95	11,66	N	0,54	P	0,92	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9726	9726	A	C	MI.7735	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	520	174	T	P	Acc/Ccc	-6,58	0	0	probably_damaging	0,99	neutral	0,15	neutral	2,46	neutral	-2,73	deleterious	-5,11	high_impact	4,34	neutral	0,63	damaging	0,05	deleterious	3,54	23,1	0,04	0,35	disease	0,55	disease	0,91	disease	0,72	disease	0,78	6	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-2,81	medium_impact	-0,24	high_impact	2,71	0,31	0,8	73,56	11,63	N	0,36	N	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9726	9726	A	T	MI.7736	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	520	174	T	S	Acc/Tcc	-6,58	0	0	probably_damaging	0,91	neutral	0,36	neutral	2,5	neutral	-0,74	deleterious	-2,67	low_impact	1,8	damaging	0,5	damaging	0,12	deleterious	2,21	17,57	0,37	0,5	neutral	0,33	disease	0,51	neutral	0,36	neutral	0,43	1	neutral	0,92	neutral	0,23	neutral	-2	deleterious	0,68	low_impact	-1,85	medium_impact	0,05	medium_impact	0,43	0,52	0,8	73,56	11,63	N	0,31	N	0,77	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9726	9726	A	G	MI.7737	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	520	174	T	A	Acc/Gcc	-6,58	0	0	probably_damaging	0,91	neutral	0,43	neutral	2,51	neutral	-0,19	deleterious	-3,98	medium_impact	3,37	neutral	0,64	damaging	0,04	deleterious	3,54	23,1	0,22	0,45	neutral	0,19	disease	0,71	disease	0,59	disease	0,65	3	neutral	0,91	neutral	0,26	deleterious	1	deleterious	0,67	low_impact	-1,85	medium_impact	0,12	medium_impact	1,84	0,27	0,8	73,56	11,63	N	0,26	N	0,44	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9727	9727	C	T	MI.7738	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	521	174	T	I	aCc/aTc	6,84	1	0	probably_damaging	0,99	neutral	0,43	neutral	2,56	neutral	0,4	deleterious	-5,28	medium_impact	2,61	neutral	0,63	damaging	0,02	deleterious	4,03	23,6	0,1	0,4	neutral	0,16	disease	0,88	disease	0,51	disease	0,66	3	deleterious	0,99	neutral	0,22	deleterious	1	deleterious	0,73	low_impact	-2,81	medium_impact	0,12	medium_impact	1,16	0,5	0,8	73,56	11,63	N	0,34	N	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9727	9727	C	G	MI.7739	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	521	174	T	S	aCc/aGc	6,84	1	0	probably_damaging	0,91	neutral	0,36	neutral	2,5	neutral	-0,74	deleterious	-2,67	low_impact	1,8	damaging	0,5	damaging	0,12	deleterious	2,46	19,18	0,37	0,5	neutral	0,33	disease	0,51	neutral	0,36	neutral	0,43	1	neutral	0,92	neutral	0,23	neutral	-2	deleterious	0,68	low_impact	-1,85	medium_impact	0,05	medium_impact	0,43	0,52	0,8	73,56	11,63	P	0,52	P	0,77	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8890	8890	A	G	MI.774	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	364	122	K	E	Aaa/Gaa	-20	0	0	probably_damaging	0,99	neutral	0,45	neutral	4,4	neutral	0,18	neutral	-2,25	low_impact	1,93	neutral	0,88	damaging	0,17	deleterious	4,03	23,7	0,46	0,65	disease	0,71	disease	0,75	disease	0,67	disease	0,64	3	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,85	low_impact	-2,65	medium_impact	0,24	medium_impact	0,56	0,68	0,9	47,35	8,39	N	0,22	N	0,85	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	A8890G	Juevnile-onset metabolic syndrome	-	+	Reported	1
chrM	9727	9727	C	A	MI.7740	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	521	174	T	N	aCc/aAc	6,84	1	0	probably_damaging	0,99	neutral	0,23	neutral	2,45	neutral	-2,56	deleterious	-3,98	high_impact	4	neutral	0,66	damaging	0,02	deleterious	3,71	23,3	0,27	0,45	neutral	0,49	disease	0,89	disease	0,61	disease	0,7	4	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,78	low_impact	-2,81	medium_impact	-0,11	high_impact	2,4	0,5	0,8	73,56	11,63	N	0,48	N	0,89	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9729	9729	C	A	MI.7741	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	523	175	L	I	Ctc/Atc	-10,51	0	0	probably_damaging	0,93	neutral	0,48	neutral	2,56	neutral	-0,26	neutral	-0,01	neutral_impact	0,68	neutral	0,84	neutral	0,77	deleterious	0,46	7,16	0,32	0,5	neutral	0,14	neutral	0,11	neutral	0,19	neutral	0,29	4	neutral	0,93	neutral	0,28	neutral	-2	deleterious	0,49	low_impact	-1,96	medium_impact	0,17	medium_impact	-0,57	0,63	0,8	22,99	37,57	N	0,44	N	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9729	9729	C	G	MI.7742	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	523	175	L	V	Ctc/Gtc	-10,51	0	0	possibly_damaging	0,83	neutral	0,36	neutral	2,59	neutral	0,52	neutral	0,09	neutral_impact	0,74	neutral	0,77	neutral	0,8	neutral	-0,31	0,62	0,28	0,45	neutral	0,13	neutral	0,24	neutral	0,25	neutral	0,41	2	neutral	0,85	neutral	0,27	neutral	-3	deleterious	0,49	low_impact	-1,54	medium_impact	0,05	medium_impact	-0,52	0,61	0,8	22,99	37,57	N	0,38	N	0,35	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9729	9729	C	T	MI.7743	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	523	175	L	F	Ctc/Ttc	-10,51	0	0	probably_damaging	0,97	neutral	0,81	neutral	2,51	neutral	-0,92	neutral	-0,88	neutral_impact	0,34	neutral	0,79	neutral	0,86	deleterious	0,06	3,21	0,27	0,45	neutral	0,23	neutral	0,27	neutral	0,2	neutral	0,43	1	neutral	0,97	neutral	0,42	neutral	-2	deleterious	0,63	low_impact	-2,34	medium_impact	0,55	medium_impact	-0,88	0,59	0,8	22,99	37,57	N	0,31	N	0,49	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9730	9730	T	G	MI.7744	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	524	175	L	R	cTc/cGc	-0,1	0	0	probably_damaging	0,99	neutral	0,31	neutral	2,46	neutral	-2,72	neutral	-2,04	medium_impact	2,69	neutral	0,64	neutral	0,36	deleterious	2,31	18,23	0,02	0,35	neutral	0,33	disease	0,75	disease	0,51	disease	0,59	2	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,75	low_impact	-2,81	medium_impact	-0,01	medium_impact	1,23	0,32	0,8	22,99	37,57	N	0,32	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9730	9730	T	A	MI.7745	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	524	175	L	H	cTc/cAc	-0,1	0	0	probably_damaging	0,99	neutral	0,38	neutral	2,45	deleterious	-3,3	neutral	-2,46	medium_impact	3,25	neutral	0,74	neutral	0,39	deleterious	2,14	17,12	0,04	0,35	neutral	0,43	disease	0,55	neutral	0,44	neutral	0,48	0	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,71	low_impact	-2,81	medium_impact	0,07	medium_impact	1,73	0,31	0,8	22,99	37,57	N	0,37	N	0,84	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9730	9730	T	C	MI.7746	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	524	175	L	P	cTc/cCc	-0,1	0	0	probably_damaging	1	neutral	0,14	neutral	2,45	deleterious	-3,36	neutral	-2,31	medium_impact	3,25	damaging	0,55	damaging	0,26	deleterious	2,48	19,33	0,02	0,35	neutral	0,45	disease	0,81	disease	0,54	disease	0,73	5	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,8	low_impact	-3,78	medium_impact	-0,26	medium_impact	1,73	0,38	0,8	22,99	37,57	N	0,33	N	0,93	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9732	9732	C	A	MI.7747	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	526	176	L	M	Cta/Ata	-8,66	0	0	possibly_damaging	0,78	neutral	0,2	neutral	2,12	neutral	-1,44	neutral	-1,89	medium_impact	2,8	damaging	0,53	damaging	0,03	deleterious	3,74	23,3	0,24	0,45	neutral	0,36	disease	0,56	neutral	0,48	neutral	0,47	1	neutral	0,87	neutral	0,21	NA	0	deleterious	0,58	low_impact	-1,4	medium_impact	-0,15	medium_impact	1,33	0,61	0,8	73,95	11,53	N	0,32	N	0,85	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9732	9732	C	G	MI.7748	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	526	176	L	V	Cta/Gta	-8,66	0	0	benign	0	neutral	0,28	neutral	2,25	neutral	-0,31	deleterious	-2,76	medium_impact	2,33	damaging	0,51	damaging	0,03	neutral	1,54	13,53	0,23	0,45	neutral	0,16	disease	0,51	disease	0,51	neutral	0,42	2	neutral	0,72	deleterious	0,64	neutral	-3	neutral	0,15	high_impact	2,05	medium_impact	-0,04	medium_impact	0,91	0,54	0,8	73,95	11,53	N	0,35	N	0,81	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9733	9733	T	G	MI.7749	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	527	176	L	R	cTa/cGa	1,05	0,43	0	possibly_damaging	0,83	neutral	0,19	neutral	2,09	deleterious	-3,56	deleterious	-5,75	high_impact	4,38	neutral	0,67	damaging	0,02	deleterious	4,21	23,9	0,03	0,35	neutral	0,47	disease	0,9	disease	0,71	disease	0,78	6	neutral	0,9	neutral	0,18	deleterious	1	deleterious	0,77	low_impact	-1,54	medium_impact	-0,17	high_impact	2,74	0,25	0,8	73,95	11,53	N	0,38	N	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8891	8891	A	C	MI.775	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	365	122	K	T	aAa/aCa	3,83	0,99	0	probably_damaging	0,99	neutral	1	neutral	4,42	neutral	0,51	neutral	-1,47	neutral_impact	-0,86	neutral	0,74	neutral	0,39	neutral	0,94	10,3	0,34	0,65	disease	0,51	neutral	0,14	neutral	0,24	neutral	0,23	5	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,72	low_impact	-2,65	high_impact	1,98	low_impact	-1,83	0,53	0,9	47,35	8,39	N	0,36	N	0,81	polymorphism	0,84	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9733	9733	T	A	MI.7750	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	527	176	L	Q	cTa/cAa	1,05	0,43	0	possibly_damaging	0,88	neutral	0,44	neutral	2,09	deleterious	-3,73	deleterious	-5,75	high_impact	4,38	neutral	0,61	damaging	0,02	deleterious	4,1	23,7	0,06	0,35	neutral	0,49	disease	0,8	disease	0,58	disease	0,66	3	neutral	0,87	neutral	0,28	deleterious	1	deleterious	0,73	low_impact	-1,71	medium_impact	0,13	high_impact	2,74	0,33	0,8	73,95	11,53	N	0,34	N	0,97	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9733	9733	T	C	MI.7751	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	527	176	L	P	cTa/cCa	1,05	0,43	0	probably_damaging	0,94	neutral	0,11	neutral	2,07	deleterious	-3,95	deleterious	-6,68	high_impact	3,83	damaging	0,55	damaging	0,03	deleterious	3,94	23,6	0,03	0,35	disease	0,57	disease	0,86	disease	0,71	disease	0,76	5	neutral	0,98	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-2,03	medium_impact	-0,33	high_impact	2,25	0,29	0,8	73,95	11,53	N	0,32	N	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9735	9735	C	G	MI.7752	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	529	177	Q	E	Caa/Gaa	-13,06	0	0	probably_damaging	0,95	neutral	0,31	neutral	2,18	neutral	-1,6	deleterious	-2,89	high_impact	3,81	neutral	0,77	damaging	0,01	deleterious	3,2	22,7	0,13	0,4	neutral	0,2	disease	0,73	disease	0,77	disease	0,72	4	neutral	0,96	neutral	0,18	deleterious	2	deleterious	0,72	low_impact	-2,11	medium_impact	-0,01	high_impact	2,23	0,43	0,8	74,33	11,67	N	0,36	N	0,95	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9735	9735	C	A	MI.7753	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	529	177	Q	K	Caa/Aaa	-13,06	0	0	probably_damaging	1	neutral	0,29	neutral	2,16	neutral	-1,74	deleterious	-3,86	high_impact	3,81	neutral	0,76	damaging	0,01	deleterious	4,04	23,7	0,09	0,35	neutral	0,19	disease	0,84	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	-0,03	high_impact	2,23	0,4	0,8	74,33	11,67	N	0,36	N	0,98	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9736	9736	A	T	MI.7754	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	530	177	Q	L	cAa/cTa	4,52	1	0	probably_damaging	1	neutral	0,68	neutral	1,96	deleterious	-4,83	deleterious	-6,75	high_impact	4,24	neutral	0,64	damaging	0,02	deleterious	3,72	23,3	0,03	0,35	disease	0,52	disease	0,9	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	0,38	high_impact	2,62	0,2	0,8	74,33	11,67	N	0,46	N	0,98	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9736	9736	A	C	MI.7755	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	530	177	Q	P	cAa/cCa	4,52	1	0	probably_damaging	0,99	neutral	0,2	neutral	1,96	deleterious	-5,23	deleterious	-5,79	high_impact	4,79	neutral	0,71	damaging	0,04	deleterious	3,28	22,8	0,03	0,35	disease	0,6	disease	0,87	disease	0,81	disease	0,77	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-2,81	medium_impact	-0,15	high_impact	3,11	0,3	0,8	74,33	11,67	P	0,67	P	0,98	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9736	9736	A	G	MI.7756	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	530	177	Q	R	cAa/cGa	4,52	1	0	probably_damaging	1	neutral	0,34	neutral	2,02	deleterious	-3,18	deleterious	-3,86	high_impact	4,79	neutral	0,84	damaging	0,02	deleterious	3,44	23	0,09	0,35	neutral	0,32	disease	0,87	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	0,03	high_impact	3,11	0,28	0,8	74,33	11,67	P	0,71	P	0,98	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9737	9737	A	C	MI.7757	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	531	177	Q	H	caA/caC	8,69	1	0	probably_damaging	1	neutral	0,54	neutral	1,96	deleterious	-5,31	deleterious	-4,82	high_impact	4,09	neutral	0,63	damaging	0,01	deleterious	3,52	23,1	0,07	0,35	neutral	0,4	disease	0,81	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	0,23	high_impact	2,48	0,56	0,8	74,33	11,67	P	0,53	P	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9737	9737	A	T	MI.7758	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	531	177	Q	H	caA/caT	8,69	1	0	probably_damaging	1	neutral	0,54	neutral	1,96	deleterious	-5,31	deleterious	-4,82	high_impact	4,09	neutral	0,63	damaging	0,01	deleterious	3,7	23,3	0,07	0,35	neutral	0,4	disease	0,81	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	0,23	high_impact	2,48	0,56	0,8	74,33	11,67	P	0,55	P	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9738	9738	G	A	MI.7759	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	532	178	A	T	Gcc/Acc	0,82	0,99	0	benign	0,06	neutral	0,38	neutral	2,48	neutral	-1,93	deleterious	-2,83	medium_impact	3,39	neutral	0,63	neutral	0,59	deleterious	2,45	19,14	0,16	0,45	neutral	0,18	disease	0,68	neutral	0,38	neutral	0,49	0	neutral	0,58	deleterious	0,66	neutral	-3	neutral	0,23	medium_impact	0,29	medium_impact	0,07	medium_impact	1,86	0,72	0,85	21,07	51,57	P	0,55	P	0,81	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8891	8891	A	T	MI.776	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	365	122	K	M	aAa/aTa	3,83	0,99	0	probably_damaging	1	neutral	0,15	neutral	4,38	neutral	-0,34	deleterious	-3,44	low_impact	1,45	neutral	0,87	damaging	0,15	deleterious	4,02	23,6	0,28	0,65	disease	0,73	disease	0,55	disease	0,6	disease	0,68	4	deleterious	1	neutral	0,08	neutral	-2	deleterious	0,79	low_impact	-3,6	medium_impact	-0,13	medium_impact	0,15	0,51	0,9	47,35	8,39	N	0,47	N	0,53	polymorphism	0,69	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9738	9738	G	T	MI.7760	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	532	178	A	S	Gcc/Tcc	0,82	0,99	0	benign	0,06	neutral	0,39	neutral	2,47	neutral	-2,22	neutral	-2,24	medium_impact	2,62	neutral	0,65	neutral	0,52	deleterious	1,93	15,79	0,19	0,45	neutral	0,2	disease	0,72	neutral	0,36	disease	0,5	0	neutral	0,57	deleterious	0,67	neutral	-3	neutral	0,21	medium_impact	0,29	medium_impact	0,08	medium_impact	1,17	0,57	0,8	21,07	51,57	P	0,6	P	0,44	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	G9738T	LHON	+	-	Reported	1
chrM	9738	9738	G	C	MI.7761	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	532	178	A	P	Gcc/Ccc	0,82	0,99	0	benign	0,39	neutral	0,2	neutral	2,44	deleterious	-4,17	deleterious	-3,88	high_impact	3,94	damaging	0,54	neutral	0,33	deleterious	3,58	23,2	0,03	0,35	neutral	0,48	disease	0,9	disease	0,62	disease	0,73	5	neutral	0,76	neutral	0,41	neutral	-2	deleterious	0,62	medium_impact	-0,68	medium_impact	-0,15	high_impact	2,35	0,64	0,8	21,07	51,57	N	0,45	N	0,97	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9739	9739	C	A	MI.7762	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	533	178	A	D	gCc/gAc	2,44	0,99	0	benign	0,3	neutral	0,2	neutral	2,43	deleterious	-4,59	deleterious	-4,71	high_impact	3,6	damaging	0,55	neutral	0,36	deleterious	4,32	24	0,02	0,35	neutral	0,44	disease	0,9	disease	0,62	disease	0,73	5	neutral	0,76	neutral	0,45	neutral	-2	deleterious	0,51	medium_impact	-0,51	medium_impact	-0,15	high_impact	2,04	0,48	0,8	21,07	51,57	N	0,46	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9739	9739	C	T	MI.7763	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	533	178	A	V	gCc/gTc	2,44	0,99	0	benign	0	neutral	0,5	neutral	2,59	neutral	-0,27	neutral	-2,4	low_impact	1,44	neutral	0,66	neutral	0,67	deleterious	2,47	19,24	0,16	0,45	neutral	0,14	disease	0,7	neutral	0,28	neutral	0,48	0	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,15	high_impact	2,05	medium_impact	0,19	medium_impact	0,11	0,74	0,85	21,07	51,57	N	0,47	N	0,51	polymorphism	1	0,08	rs879159866	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9739	9739	C	G	MI.7764	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	533	178	A	G	gCc/gGc	2,44	0,99	0	benign	0,04	neutral	0,33	neutral	2,51	neutral	-1,34	deleterious	-2,98	neutral_impact	0,7	neutral	0,67	neutral	0,7	neutral	1,04	10,9	0,23	0,45	neutral	0,21	neutral	0,44	neutral	0,22	neutral	0,44	1	neutral	0,65	deleterious	0,65	neutral	-6	neutral	0,16	medium_impact	0,47	medium_impact	0,02	medium_impact	-0,56	0,77	0,85	21,07	51,57	P	0,53	P	0,69	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9741	9741	T	G	MI.7765	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	535	179	S	A	Tca/Gca	-5,19	0	0	possibly_damaging	0,84	neutral	0,53	neutral	2,61	neutral	0,44	neutral	-0,48	low_impact	0,86	neutral	0,68	neutral	0,66	deleterious	2,44	19,07	0,22	0,45	neutral	0,15	neutral	0,25	neutral	0,32	neutral	0,43	1	neutral	0,82	neutral	0,35	neutral	-3	neutral	0,42	low_impact	-1,57	medium_impact	0,22	medium_impact	-0,41	0,44	0,8	24,14	20,87	N	0,3	N	0,37	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9741	9741	T	C	MI.7766	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	535	179	S	P	Tca/Cca	-5,19	0	0	probably_damaging	0,96	neutral	0,19	neutral	2,55	neutral	-1,05	neutral	-1,83	medium_impact	1,96	damaging	0,48	damaging	0,25	deleterious	2,92	22	0,09	0,35	neutral	0,39	disease	0,81	neutral	0,49	disease	0,69	4	neutral	0,97	neutral	0,12	deleterious	1	deleterious	0,77	low_impact	-2,21	medium_impact	-0,17	medium_impact	0,57	0,32	0,8	24,14	20,87	N	0,39	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9741	9741	T	A	MI.7767	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	535	179	S	T	Tca/Aca	-5,19	0	0	possibly_damaging	0,74	neutral	0,37	neutral	2,61	neutral	0,51	neutral	-0,37	neutral_impact	0,33	neutral	0,7	neutral	0,69	deleterious	2,46	19,19	0,19	0,45	neutral	0,14	neutral	0,25	neutral	0,33	neutral	0,42	2	neutral	0,76	neutral	0,32	neutral	-3	deleterious	0,5	low_impact	-1,31	medium_impact	0,06	medium_impact	-0,89	0,5	0,8	24,14	20,87	N	0,37	N	0,61	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9742	9742	C	T	MI.7768	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	536	179	S	L	tCa/tTa	4,06	0,87	0	probably_damaging	0,97	neutral	0,66	neutral	2,69	neutral	1,55	neutral	0,21	neutral_impact	-0,72	neutral	0,73	neutral	0,72	deleterious	2,99	22,2	0,11	0,4	neutral	0,11	neutral	0,47	neutral	0,26	neutral	0,42	2	neutral	0,97	neutral	0,35	neutral	-2	deleterious	0,65	low_impact	-2,34	medium_impact	0,36	low_impact	-1,83	0,41	0,8	24,14	20,87	N	0,36	N	0,93	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9742	9742	C	G	MI.7769	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	536	179	S	W	tCa/tGa	4,06	0,87	0	probably_damaging	1	neutral	0,17	neutral	2,62	neutral	0,64	neutral	1,18	neutral_impact	0,44	neutral	0,69	neutral	0,62	deleterious	3,19	22,7	0,07	0,35	disease	0,54	disease	0,7	neutral	0,35	disease	0,52	0	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,76	low_impact	-3,78	medium_impact	-0,2	medium_impact	-0,79	0,18	0,8	24,14	20,87	N	0,37	N	1	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8892	8892	A	T	MI.777	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	366	122	K	N	aaA/aaT	6,14	1	0	probably_damaging	1	neutral	0,77	neutral	4,41	neutral	0,41	neutral	-2,43	neutral_impact	0,02	neutral	0,87	damaging	0,16	deleterious	2,53	19,66	0,59	0,7	disease	0,76	neutral	0,46	neutral	0,32	disease	0,64	3	deleterious	0,99	neutral	0,39	neutral	-2	deleterious	0,82	low_impact	-3,6	medium_impact	0,59	low_impact	-1,08	0,8	0,9	47,35	8,39	N	0,44	N	0,76	polymorphism	0,68	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9744	9744	G	C	MI.7770	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	538	180	E	Q	Gag/Cag	-0,33	0,34	0	probably_damaging	0,98	neutral	0,24	neutral	1,2	deleterious	-5,81	deleterious	-2,89	high_impact	4,78	damaging	0,55	neutral	0,52	deleterious	3,45	23	0,07	0,35	disease	0,77	disease	0,79	disease	0,78	disease	0,77	5	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,84	low_impact	-2,51	medium_impact	-0,09	high_impact	3,1	0,59	0,8	73,18	11,71	P	0,7	P	0,87	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9744	9744	G	A	MI.7771	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	538	180	E	K	Gag/Aag	-0,33	0,34	0	probably_damaging	0,98	neutral	0,2	neutral	1,2	deleterious	-5,7	deleterious	-3,86	high_impact	4,08	damaging	0,43	neutral	0,29	deleterious	4,55	24,3	0,03	0,35	disease	0,73	disease	0,87	disease	0,76	disease	0,77	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-2,51	medium_impact	-0,15	high_impact	2,47	0,77	0,85	73,18	11,71	P	0,57	P	0,97	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9745	9745	A	T	MI.7772	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	539	180	E	V	gAg/gTg	7,3	1	0	probably_damaging	0,99	neutral	0,37	neutral	1,17	deleterious	-7,52	deleterious	-6,75	high_impact	4,42	damaging	0,46	neutral	0,46	deleterious	4,22	23,9	0,02	0,35	disease	0,87	disease	0,89	disease	0,78	disease	0,83	7	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,87	low_impact	-2,81	medium_impact	0,06	high_impact	2,78	0,28	0,8	73,18	11,71	P	0,66	P	0,83	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9745	9745	A	G	MI.7773	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	539	180	E	G	gAg/gGg	7,3	1	0	probably_damaging	0,99	neutral	0,25	neutral	1,18	deleterious	-6,65	deleterious	-6,74	high_impact	4,78	damaging	0,46	neutral	0,57	deleterious	4,19	23,8	0,03	0,35	disease	0,77	disease	0,82	disease	0,75	disease	0,77	5	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,85	low_impact	-2,81	medium_impact	-0,08	high_impact	3,1	0,11	0,8	73,18	11,71	P	0,68	P	0,62	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9745	9745	A	C	MI.7774	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	539	180	E	A	gAg/gCg	7,3	1	0	probably_damaging	0,98	neutral	0,44	neutral	1,25	deleterious	-4,62	deleterious	-5,78	high_impact	4,42	damaging	0,56	neutral	0,53	deleterious	3,63	23,2	0,03	0,35	disease	0,76	disease	0,73	disease	0,75	disease	0,76	5	deleterious	0,98	neutral	0,23	deleterious	2	deleterious	0,83	low_impact	-2,51	medium_impact	0,13	high_impact	2,78	0,27	0,8	73,18	11,71	P	0,62	P	0,66	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9746	9746	G	T	MI.7775	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	540	180	E	D	gaG/gaT	8,69	1	0	probably_damaging	0,92	neutral	0,14	neutral	1,31	deleterious	-3,94	deleterious	-2,89	high_impact	4,78	damaging	0,51	neutral	0,49	deleterious	3,89	23,5	0,11	0,4	disease	0,61	disease	0,78	disease	0,73	disease	0,74	5	neutral	0,96	neutral	0,11	deleterious	2	deleterious	0,77	low_impact	-1,9	medium_impact	-0,26	high_impact	3,1	0,58	0,8	73,18	11,71	P	0,76	P	0,93	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9746	9746	G	C	MI.7776	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	540	180	E	D	gaG/gaC	8,69	1	0	probably_damaging	0,92	neutral	0,14	neutral	1,31	deleterious	-3,94	deleterious	-2,89	high_impact	4,78	damaging	0,51	neutral	0,49	deleterious	3,76	23,3	0,11	0,4	disease	0,61	disease	0,78	disease	0,73	disease	0,74	5	neutral	0,96	neutral	0,11	deleterious	2	deleterious	0,77	low_impact	-1,9	medium_impact	-0,26	high_impact	3,1	0,58	0,8	73,18	11,71	P	0,76	P	0,93	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9747	9747	T	A	MI.7777	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	541	181	Y	N	Tac/Aac	-2,19	0	0	probably_damaging	1	neutral	0,27	neutral	1,75	deleterious	-8,27	deleterious	-8,68	high_impact	4,74	neutral	0,6	damaging	0,01	deleterious	4,29	24	0,02	0,35	disease	0,84	disease	0,87	disease	0,73	disease	0,8	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	-0,06	high_impact	3,07	0,05	0,8	73,56	11,67	P	0,52	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9747	9747	T	C	MI.7778	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	541	181	Y	H	Tac/Cac	-2,19	0	0	probably_damaging	1	neutral	0,45	neutral	1,76	deleterious	-6,81	deleterious	-4,82	high_impact	4,19	damaging	0,56	damaging	0,03	deleterious	3,69	23,3	0,04	0,35	disease	0,69	disease	0,81	disease	0,74	disease	0,75	5	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	0,14	high_impact	2,57	0,09	0,8	73,56	11,67	N	0,32	N	0,97	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9747	9747	T	G	MI.7779	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	541	181	Y	D	Tac/Gac	-2,19	0	0	probably_damaging	1	neutral	0,19	neutral	1,75	deleterious	-9,07	deleterious	-9,64	high_impact	4,74	neutral	0,65	damaging	0,01	deleterious	4,05	23,7	0,01	0,35	disease	0,92	disease	0,87	disease	0,8	disease	0,86	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	-0,17	high_impact	3,07	0,05	0,8	73,56	11,67	N	0,51	P	0,99	disease_causing	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8892	8892	A	C	MI.778	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	366	122	K	N	aaA/aaC	6,14	1	0	probably_damaging	1	neutral	0,77	neutral	4,41	neutral	0,41	neutral	-2,43	neutral_impact	0,02	neutral	0,87	damaging	0,16	deleterious	2,44	19,1	0,59	0,7	disease	0,76	neutral	0,46	neutral	0,32	disease	0,64	3	deleterious	0,99	neutral	0,39	neutral	-2	deleterious	0,82	low_impact	-3,6	medium_impact	0,59	low_impact	-1,08	0,8	0,9	47,35	8,39	N	0,43	N	0,76	polymorphism	0,68	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9748	9748	A	T	MI.7780	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	542	181	Y	F	tAc/tTc	7,53	1	0	probably_damaging	0,98	neutral	0,62	neutral	2,19	neutral	-1,15	deleterious	-3,86	medium_impact	3,33	damaging	0,6	damaging	0,03	deleterious	3,52	23,1	0,15	0,4	neutral	0,29	disease	0,8	disease	0,61	disease	0,63	3	deleterious	0,98	neutral	0,32	deleterious	1	deleterious	0,76	low_impact	-2,51	medium_impact	0,31	medium_impact	1,8	0,33	0,8	73,56	11,67	N	0,44	N	0,72	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9748	9748	A	C	MI.7781	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	542	181	Y	S	tAc/tCc	7,53	1	0	probably_damaging	1	neutral	0,42	neutral	1,75	deleterious	-7,47	deleterious	-8,68	high_impact	4,74	neutral	0,65	damaging	0,02	deleterious	3,81	23,4	0,02	0,35	disease	0,82	disease	0,85	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	0,11	high_impact	3,07	0,06	0,8	73,56	11,67	P	0,6	P	0,96	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9748	9748	A	G	MI.7782	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	542	181	Y	C	tAc/tGc	7,53	1	0	probably_damaging	1	neutral	0,15	neutral	1,75	deleterious	-7,89	deleterious	-8,68	high_impact	4,74	neutral	0,68	damaging	0,02	deleterious	3,62	23,2	0,02	0,35	disease	0,92	disease	0,87	disease	0,77	disease	0,84	7	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	-0,24	high_impact	3,07	0,1	0,8	73,56	11,67	P	0,62	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9750	9750	T	A	MI.7783	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	544	182	F	I	Ttc/Atc	-1,72	0	0	benign	0	neutral	0,36	neutral	2,62	neutral	-0,16	neutral	-0,57	neutral_impact	-0,63	neutral	0,78	neutral	0,77	neutral	1,35	12,52	0,11	0,4	neutral	0,11	neutral	0,21	neutral	0,16	neutral	0,36	3	neutral	0,64	deleterious	0,68	neutral	-6	neutral	0,11	high_impact	2,05	medium_impact	0,05	low_impact	-1,75	0,6	0,8	26,05	34,16	N	0,47	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9750	9750	T	C	MI.7784	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	544	182	F	L	Ttc/Ctc	-1,72	0	0	benign	0,01	neutral	0,56	neutral	2,66	neutral	-0,14	neutral	-0,5	neutral_impact	0,13	neutral	0,75	neutral	0,82	neutral	1,04	10,87	0,16	0,45	neutral	0,11	neutral	0,25	neutral	0,18	neutral	0,41	2	neutral	0,42	deleterious	0,78	neutral	-6	neutral	0,11	medium_impact	1,07	medium_impact	0,25	low_impact	-1,07	0,5	0,8	26,05	34,16	N	0,43	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9750	9750	T	G	MI.7785	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	544	182	F	V	Ttc/Gtc	-1,72	0	0	benign	0,02	neutral	0,41	neutral	2,61	neutral	-0,34	neutral	-0,83	neutral_impact	-0,44	neutral	0,75	neutral	0,78	neutral	1,23	11,89	0,1	0,4	neutral	0,1	neutral	0,37	neutral	0,18	neutral	0,43	1	neutral	0,58	deleterious	0,7	neutral	-6	neutral	0,11	medium_impact	0,77	medium_impact	0,1	low_impact	-1,58	0,31	0,8	26,05	34,16	N	0,47	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9751	9751	T	G	MI.7786	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	545	182	F	C	tTc/tGc	4,52	0,99	0	possibly_damaging	0,63	neutral	0,14	neutral	2,53	deleterious	-3,33	deleterious	-2,55	low_impact	1,12	neutral	0,66	neutral	0,52	deleterious	3,91	23,5	0,07	0,35	neutral	0,38	disease	0,59	neutral	0,38	neutral	0,47	1	neutral	0,87	neutral	0,26	neutral	-3	deleterious	0,54	low_impact	-1,09	medium_impact	-0,26	medium_impact	-0,18	0,14	0,8	26,05	34,16	N	0,48	N	0,78	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9751	9751	T	C	MI.7787	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	545	182	F	S	tTc/tCc	4,52	0,99	0	benign	0,13	neutral	0,34	neutral	2,64	neutral	-0,8	deleterious	-2,58	neutral_impact	-0,48	neutral	0,74	neutral	0,87	deleterious	2,35	18,51	0,05	0,35	neutral	0,13	neutral	0,32	neutral	0,27	neutral	0,43	1	neutral	0,6	deleterious	0,61	neutral	-6	neutral	0,18	medium_impact	-0,07	medium_impact	0,03	low_impact	-1,61	0,15	0,8	26,05	34,16	N	0,52	P	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9751	9751	T	A	MI.7788	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	545	182	F	Y	tTc/tAc	4,52	0,99	0	benign	0	neutral	1	neutral	2,63	neutral	-0,91	neutral	0,48	neutral_impact	-1,61	neutral	0,78	neutral	0,99	neutral	-0,31	0,65	0,18	0,45	neutral	0,12	neutral	0,09	neutral	0,12	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,11	high_impact	2,05	high_impact	1,9	low_impact	-2,63	0,67	0,85	26,05	34,16	N	0,5	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9752	9752	C	G	MI.7789	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	546	182	F	L	ttC/ttG	2,9	0,98	0	benign	0,01	neutral	0,56	neutral	2,66	neutral	-0,14	neutral	-0,5	neutral_impact	0,13	neutral	0,75	neutral	0,82	neutral	1,21	11,8	0,16	0,45	neutral	0,11	neutral	0,25	neutral	0,18	neutral	0,41	2	neutral	0,42	deleterious	0,78	neutral	-6	neutral	0,11	medium_impact	1,07	medium_impact	0,25	low_impact	-1,07	0,5	0,8	26,05	34,16	P	0,51	P	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8893	8893	A	G	MI.779	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	367	123	N	D	Aat/Gat	-1,03	0	0	benign	0,11	neutral	0,59	neutral	3,89	neutral	-0,57	neutral	-0,99	neutral_impact	0,38	neutral	0,91	neutral	0,57	deleterious	0,35	6,19	0,8	0,85	neutral	0,28	neutral	0,45	neutral	0,32	neutral	0,47	1	neutral	0,31	deleterious	0,74	neutral	-6	neutral	0,28	medium_impact	0,11	medium_impact	0,38	medium_impact	-0,77	0,63	0,9	24,34	21,11	N	0,3	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9752	9752	C	A	MI.7790	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	546	182	F	L	ttC/ttA	2,9	0,98	0	benign	0,01	neutral	0,56	neutral	2,66	neutral	-0,14	neutral	-0,5	neutral_impact	0,13	neutral	0,75	neutral	0,82	neutral	1,48	13,22	0,16	0,45	neutral	0,11	neutral	0,25	neutral	0,18	neutral	0,41	2	neutral	0,42	deleterious	0,78	neutral	-6	neutral	0,11	medium_impact	1,07	medium_impact	0,25	low_impact	-1,07	0,5	0,8	26,05	34,16	N	0,5	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9753	9753	G	C	MI.7791	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	547	183	E	Q	Gag/Cag	-4,04	0	0	probably_damaging	0,98	neutral	0,29	neutral	2,48	neutral	-1,5	neutral	-2,2	medium_impact	2,37	damaging	0,52	neutral	0,55	deleterious	3,44	23	0,31	0,45	neutral	0,22	disease	0,59	neutral	0,25	neutral	0,41	2	deleterious	0,98	neutral	0,16	deleterious	1	deleterious	0,7	low_impact	-2,51	medium_impact	-0,03	medium_impact	0,94	0,54	0,8	73,95	11,58	N	0,44	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9753	9753	G	A	MI.7792	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	547	183	E	K	Gag/Aag	-4,04	0	0	probably_damaging	0,98	neutral	0,27	neutral	2,47	neutral	-0,98	deleterious	-3,29	medium_impact	2,83	damaging	0,56	neutral	0,39	deleterious	4,54	24,3	0,12	0,4	neutral	0,2	disease	0,83	disease	0,54	disease	0,68	4	deleterious	0,98	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-2,51	medium_impact	-0,06	medium_impact	1,35	0,77	0,85	73,95	11,58	N	0,35	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9754	9754	A	C	MI.7793	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	548	183	E	A	gAg/gCg	6,14	1	0	probably_damaging	0,98	neutral	0,5	neutral	2,51	neutral	-1,56	deleterious	-5,03	medium_impact	2,83	neutral	0,64	neutral	0,61	deleterious	3,88	23,5	0,13	0,4	neutral	0,25	disease	0,65	neutral	0,5	neutral	0,49	0	deleterious	0,98	neutral	0,26	deleterious	1	deleterious	0,71	low_impact	-2,51	medium_impact	0,19	medium_impact	1,35	0,26	0,8	73,95	11,58	N	0,49	N	0,66	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9754	9754	A	T	MI.7794	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	548	183	E	V	gAg/gTg	6,14	1	0	probably_damaging	0,99	neutral	0,48	neutral	2,49	neutral	-2,94	deleterious	-5,91	medium_impact	2,09	damaging	0,51	neutral	0,53	deleterious	4,43	24,2	0,07	0,35	neutral	0,36	disease	0,82	neutral	0,43	disease	0,52	0	deleterious	0,99	neutral	0,25	deleterious	1	deleterious	0,76	low_impact	-2,81	medium_impact	0,17	medium_impact	0,69	0,29	0,8	73,95	11,58	N	0,45	N	0,83	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9754	9754	A	G	MI.7795	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	548	183	E	G	gAg/gGg	6,14	1	0	probably_damaging	0,99	neutral	0,32	neutral	2,47	neutral	-2,12	deleterious	-5,9	medium_impact	2,76	damaging	0,54	neutral	0,64	deleterious	4,45	24,2	0,11	0,4	neutral	0,33	disease	0,74	disease	0,52	disease	0,55	1	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,74	low_impact	-2,81	medium_impact	0,01	medium_impact	1,29	0,22	0,8	73,95	11,58	N	0,46	N	0,62	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9755	9755	G	C	MI.7796	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	549	183	E	D	gaG/gaC	8,69	1	0,03	probably_damaging	0,92	neutral	0,19	neutral	2,47	neutral	-1,77	neutral	-2,34	medium_impact	1,98	neutral	0,62	neutral	0,66	deleterious	2,72	20,9	0,35	0,5	neutral	0,29	disease	0,62	neutral	0,24	neutral	0,41	2	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,63	low_impact	-1,9	medium_impact	-0,17	medium_impact	0,59	0,63	0,8	73,95	11,58	P	0,55	P	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9755	9755	G	T	MI.7797	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	549	183	E	D	gaG/gaT	8,69	1	0,03	probably_damaging	0,92	neutral	0,19	neutral	2,47	neutral	-1,77	neutral	-2,34	medium_impact	1,98	neutral	0,62	neutral	0,66	deleterious	2,87	21,7	0,35	0,5	neutral	0,29	disease	0,62	neutral	0,24	neutral	0,41	2	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,63	low_impact	-1,9	medium_impact	-0,17	medium_impact	0,59	0,63	0,8	73,95	11,58	P	0,57	P	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9756	9756	T	C	MI.7798	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	550	184	S	P	Tct/Cct	1,75	0,98	0	benign	0,13	neutral	0,23	neutral	2,17	neutral	-2,53	neutral	-2,38	low_impact	1,66	damaging	0,44	neutral	0,33	deleterious	2,24	17,79	0,08	0,35	neutral	0,33	disease	0,87	disease	0,53	disease	0,76	5	neutral	0,74	deleterious	0,55	neutral	-6	neutral	0,28	medium_impact	-0,07	medium_impact	-0,11	medium_impact	0,31	0,12	0,8	14,18	37,72	P	0,6	P	0,54	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9756	9756	T	A	MI.7799	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	550	184	S	T	Tct/Act	1,75	0,98	0	benign	0,05	neutral	0,44	neutral	2,25	neutral	-0,8	neutral	-0,56	neutral_impact	-0,04	neutral	0,75	neutral	0,93	neutral	0,91	10,13	0,38	0,5	neutral	0,12	neutral	0,28	neutral	0,23	neutral	0,4	2	neutral	0,52	deleterious	0,7	neutral	-6	neutral	0,12	medium_impact	0,37	medium_impact	0,13	low_impact	-1,22	0,48	0,8	14,18	37,72	N	0,52	P	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8560	8560	C	G	MI.78	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	34	12	P	A	Ccc/Gcc	0,36	0,11	0	probably_damaging	1	neutral	0,07	neutral	4,67	neutral	0,7	deleterious	-6,91	medium_impact	2,67	neutral	0,61	damaging	0,09	deleterious	2,85	21,6	0,43	0,65	neutral	0,49	disease	0,62	disease	0,58	neutral	0,46	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	-0,34	medium_impact	1,19	0,8	0,9	50	8,94	N	0,32	N	0,76	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8893	8893	A	T	MI.780	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	367	123	N	Y	Aat/Tat	-1,03	0	0	possibly_damaging	0,66	neutral	0,14	neutral	4,08	neutral	2,31	neutral	-1,03	low_impact	0,86	neutral	0,89	neutral	0,68	neutral	1,13	11,37	0,49	0,65	disease	0,74	disease	0,57	neutral	0,39	neutral	0,43	1	neutral	0,88	neutral	0,24	neutral	-3	deleterious	0,63	low_impact	-1,03	medium_impact	-0,15	medium_impact	-0,36	0,53	0,9	24,34	21,11	N	0,42	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9756	9756	T	G	MI.7800	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	550	184	S	A	Tct/Gct	1,75	0,98	0	benign	0	neutral	0,58	neutral	2,63	neutral	1,56	neutral	1,42	neutral_impact	-1,63	neutral	0,73	neutral	0,99	neutral	-0,84	0,04	0,36	0,5	neutral	0,13	neutral	0,05	neutral	0,18	neutral	0,25	5	neutral	0,42	deleterious	0,79	neutral	-6	neutral	0,09	high_impact	2,05	medium_impact	0,27	low_impact	-2,64	0,25	0,8	14,18	37,72	N	0,49	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9757	9757	C	A	MI.7801	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	551	184	S	Y	tCt/tAt	-0,1	0,93	0	benign	0,37	neutral	1	neutral	2,16	deleterious	-3,37	deleterious	-3,34	medium_impact	2,01	damaging	0,54	neutral	0,54	deleterious	2,25	17,86	0,08	0,35	neutral	0,3	disease	0,73	disease	0,62	disease	0,71	4	neutral	0,37	deleterious	0,82	neutral	-3	neutral	0,3	medium_impact	-0,64	high_impact	1,9	medium_impact	0,62	0,17	0,8	14,18	37,72	N	0,35	N	0,64	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9757	9757	C	G	MI.7802	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	551	184	S	C	tCt/tGt	-0,1	0,93	0	possibly_damaging	0,44	neutral	0,18	neutral	2,16	deleterious	-3,34	neutral	-1,71	low_impact	0,9	damaging	0,5	neutral	0,4	deleterious	1,92	15,71	0,12	0,4	neutral	0,44	disease	0,71	neutral	0,46	disease	0,54	1	neutral	0,79	neutral	0,37	neutral	-3	neutral	0,32	medium_impact	-0,77	medium_impact	-0,18	medium_impact	-0,38	0,17	0,8	14,18	37,72	N	0,43	N	0,39	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9757	9757	C	T	MI.7803	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	551	184	S	F	tCt/tTt	-0,1	0,93	0	benign	0,37	neutral	0,72	neutral	2,16	deleterious	-3,24	deleterious	-3,34	low_impact	1,52	damaging	0,51	neutral	0,53	deleterious	2,51	19,54	0,11	0,4	neutral	0,18	disease	0,81	disease	0,62	disease	0,77	5	neutral	0,27	deleterious	0,68	neutral	-6	neutral	0,29	medium_impact	-0,64	medium_impact	0,43	medium_impact	0,18	0,04	0,8	14,18	37,72	N	0,39	N	0,69	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9759	9759	C	T	MI.7804	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	553	185	P	S	Ccc/Tcc	-8,66	0	0	probably_damaging	0,99	neutral	0,49	neutral	2,61	neutral	0,33	deleterious	-4,54	neutral_impact	0,07	neutral	0,7	neutral	0,88	deleterious	2,35	18,46	0,27	0,45	neutral	0,12	neutral	0,31	neutral	0,23	neutral	0,43	2	deleterious	0,99	neutral	0,25	neutral	-2	deleterious	0,66	low_impact	-2,81	medium_impact	0,18	low_impact	-1,12	0,06	0,8	70,88	9,08	N	0,3	N	0,23	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9759	9759	C	G	MI.7805	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	553	185	P	A	Ccc/Gcc	-8,66	0	0	probably_damaging	0,97	neutral	0,6	neutral	2,54	neutral	-0,7	deleterious	-5,21	medium_impact	2,08	neutral	0,68	neutral	0,55	neutral	1,49	13,26	0,23	0,45	neutral	0,15	neutral	0,43	neutral	0,46	neutral	0,44	1	neutral	0,97	neutral	0,32	deleterious	1	deleterious	0,66	low_impact	-2,34	medium_impact	0,29	medium_impact	0,68	0,63	0,8	70,88	9,08	N	0,29	N	0,57	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9759	9759	C	A	MI.7806	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	553	185	P	T	Ccc/Acc	-8,66	0	0	probably_damaging	0,99	neutral	0,4	neutral	2,53	neutral	-0,84	deleterious	-5,05	medium_impact	2	neutral	0,64	neutral	0,54	deleterious	1,88	15,46	0,2	0,45	neutral	0,23	disease	0,58	neutral	0,32	neutral	0,44	1	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,67	low_impact	-2,81	medium_impact	0,09	medium_impact	0,61	0,55	0,8	70,88	9,08	N	0,35	N	0,51	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9760	9760	C	G	MI.7807	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	554	185	P	R	cCc/cGc	0,13	0,01	0	probably_damaging	1	neutral	0,33	neutral	2,51	neutral	-1,3	deleterious	-6,26	medium_impact	3,4	neutral	0,67	neutral	0,37	deleterious	3,67	23,3	0,09	0,35	neutral	0,23	disease	0,82	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	0,02	medium_impact	1,86	0,37	0,8	70,88	9,08	N	0,34	N	0,93	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9760	9760	C	A	MI.7808	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	554	185	P	H	cCc/cAc	0,13	0,01	0	probably_damaging	1	neutral	0,54	neutral	2,51	neutral	-1,36	deleterious	-6,34	medium_impact	2,6	neutral	0,67	neutral	0,37	deleterious	4,11	23,8	0,12	0,4	neutral	0,37	disease	0,72	disease	0,62	disease	0,67	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	0,23	medium_impact	1,15	0,34	0,8	70,88	9,08	N	0,25	N	0,91	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9760	9760	C	T	MI.7809	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	554	185	P	L	cCc/cTc	0,13	0,01	0	probably_damaging	1	neutral	0,64	neutral	2,52	neutral	-1,2	deleterious	-7,28	medium_impact	2,86	neutral	0,67	neutral	0,44	deleterious	4,43	24,2	0,15	0,4	neutral	0,31	disease	0,79	disease	0,55	disease	0,67	3	deleterious	1	neutral	0,32	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	0,33	medium_impact	1,38	0,56	0,8	70,88	9,08	N	0,29	N	0,84	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8893	8893	A	C	MI.781	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	367	123	N	H	Aat/Cat	-1,03	0	0	possibly_damaging	0,66	neutral	0,33	neutral	3,95	neutral	0,97	neutral	-0,57	neutral_impact	-1,15	neutral	0,82	neutral	0,83	deleterious	0,59	8,12	0,67	0,75	neutral	0,36	neutral	0,14	neutral	0,22	neutral	0,29	4	neutral	0,73	neutral	0,34	neutral	-3	deleterious	0,52	low_impact	-1,03	medium_impact	0,12	low_impact	-2,08	0,51	0,9	24,34	21,11	N	0,38	N	0,37	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9762	9762	T	C	MI.7810	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	556	186	F	L	Ttc/Ctc	-20	0	0	probably_damaging	0,98	neutral	0,66	neutral	1,81	neutral	-2,74	deleterious	-5,79	medium_impact	2,45	neutral	0,64	damaging	0,02	deleterious	4,21	23,9	0,21	0,45	neutral	0,23	disease	0,69	disease	0,69	disease	0,61	2	deleterious	0,98	neutral	0,34	deleterious	1	deleterious	0,74	low_impact	-2,51	medium_impact	0,36	medium_impact	1,01	0,61	0,8	73,56	11,72	N	0,21	N	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9762	9762	T	A	MI.7811	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	556	186	F	I	Ttc/Atc	-20	0	0	probably_damaging	0,99	neutral	0,52	neutral	1,77	deleterious	-3,52	deleterious	-5,79	high_impact	3,86	neutral	0,68	damaging	0,02	deleterious	4,54	24,3	0,14	0,4	neutral	0,24	disease	0,74	disease	0,71	disease	0,71	4	deleterious	0,99	neutral	0,27	deleterious	2	deleterious	0,75	low_impact	-2,81	medium_impact	0,21	high_impact	2,28	0,4	0,8	73,56	11,72	N	0,26	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9762	9762	T	G	MI.7812	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	556	186	F	V	Ttc/Gtc	-20	0	0	probably_damaging	1	neutral	0,49	neutral	1,77	deleterious	-3,32	deleterious	-6,75	medium_impact	3,22	neutral	0,65	damaging	0,01	deleterious	4,28	24	0,06	0,35	neutral	0,24	disease	0,8	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,75	low_impact	-3,78	medium_impact	0,18	medium_impact	1,7	0,25	0,8	73,56	11,72	N	0,25	N	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9763	9763	T	A	MI.7813	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	557	186	F	Y	tTc/tAc	7,53	1	0	probably_damaging	0,98	neutral	1	neutral	1,91	neutral	-1,78	deleterious	-2,89	medium_impact	3,31	neutral	0,7	damaging	0,02	deleterious	4,36	24,1	0,16	0,45	neutral	0,3	disease	0,67	disease	0,64	disease	0,59	2	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,75	low_impact	-2,51	high_impact	1,9	medium_impact	1,78	0,61	0,8	73,56	11,72	N	0,46	N	0,8	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9763	9763	T	C	MI.7814	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	557	186	F	S	tTc/tCc	7,53	1	0	probably_damaging	1	neutral	0,44	neutral	1,77	deleterious	-3,49	deleterious	-7,71	high_impact	4,12	damaging	0,54	damaging	0,01	deleterious	4,38	24,1	0,03	0,35	neutral	0,3	disease	0,8	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	0,13	high_impact	2,51	0,14	0,8	73,56	11,72	N	0,5	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9763	9763	T	G	MI.7815	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	557	186	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	neutral	0,19	neutral	1,71	deleterious	-5,81	deleterious	-7,71	high_impact	4,66	neutral	0,73	damaging	0,01	deleterious	4,23	23,9	0,04	0,35	disease	0,6	disease	0,8	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,17	high_impact	2,99	0,16	0,8	73,56	11,72	P	0,57	P	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9764	9764	C	G	MI.7816	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	558	186	F	L	ttC/ttG	7,53	1	0	probably_damaging	0,98	neutral	0,66	neutral	1,81	neutral	-2,74	deleterious	-5,79	medium_impact	2,45	neutral	0,64	damaging	0,02	deleterious	4,45	24,2	0,21	0,45	neutral	0,23	disease	0,69	disease	0,69	disease	0,61	2	deleterious	0,98	neutral	0,34	deleterious	1	deleterious	0,74	low_impact	-2,51	medium_impact	0,36	medium_impact	1,01	0,61	0,8	73,56	11,72	N	0,4	N	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9764	9764	C	A	MI.7817	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	558	186	F	L	ttC/ttA	7,53	1	0	probably_damaging	0,98	neutral	0,66	neutral	1,81	neutral	-2,74	deleterious	-5,79	medium_impact	2,45	neutral	0,64	damaging	0,02	deleterious	4,76	24,7	0,21	0,45	neutral	0,23	disease	0,69	disease	0,69	disease	0,61	2	deleterious	0,98	neutral	0,34	deleterious	1	deleterious	0,74	low_impact	-2,51	medium_impact	0,36	medium_impact	1,01	0,61	0,8	73,56	11,72	N	0,41	N	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9765	9765	A	G	MI.7818	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	559	187	T	A	Acc/Gcc	-4,73	0	0	benign	0,01	neutral	0,66	neutral	2,39	neutral	-0,99	deleterious	-3,71	low_impact	1,94	neutral	0,67	neutral	0,77	neutral	1,64	14,04	0,18	0,45	neutral	0,23	neutral	0,36	neutral	0,49	neutral	0,44	1	neutral	0,33	deleterious	0,83	neutral	-6	neutral	0,13	medium_impact	1,07	medium_impact	0,36	medium_impact	0,56	0,28	0,8	63,98	10,92	N	0,37	N	0,43	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9765	9765	A	T	MI.7819	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	559	187	T	S	Acc/Tcc	-4,73	0	0	benign	0,11	neutral	0,59	neutral	2,48	neutral	-0,97	deleterious	-2,64	neutral_impact	0,34	neutral	0,65	neutral	0,71	deleterious	1,86	15,35	0,26	0,45	neutral	0,18	neutral	0,19	neutral	0,26	neutral	0,33	3	neutral	0,31	deleterious	0,74	neutral	-6	neutral	0,17	medium_impact	0,01	medium_impact	0,28	medium_impact	-0,88	0,47	0,8	63,98	10,92	N	0,33	N	0,07	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8894	8894	A	G	MI.782	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	368	123	N	S	aAt/aGt	-2,42	0	0,02	benign	0,01	neutral	0,81	neutral	3,94	neutral	0,77	neutral	0,54	neutral_impact	-0,28	neutral	0,91	neutral	0,97	neutral	-0,8	0,04	0,83	0,85	neutral	0,27	neutral	0,24	neutral	0,18	neutral	0,43	1	neutral	0,16	deleterious	0,9	neutral	-6	neutral	0,12	medium_impact	1,14	medium_impact	0,65	low_impact	-1,34	0,24	0,9	24,34	21,11	N	0,34	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9765	9765	A	C	MI.7820	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	559	187	T	P	Acc/Ccc	-4,73	0	0	possibly_damaging	0,64	neutral	0,26	neutral	2,35	neutral	-2,74	deleterious	-4,9	medium_impact	3,15	damaging	0,57	neutral	0,41	deleterious	3,55	23,1	0,04	0,35	disease	0,53	disease	0,79	disease	0,6	disease	0,67	3	neutral	0,77	neutral	0,31	NA	0	deleterious	0,68	low_impact	-1,11	medium_impact	-0,07	medium_impact	1,64	0,29	0,8	63,98	10,92	N	0,34	N	0,94	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9766	9766	C	G	MI.7821	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	560	187	T	S	aCc/aGc	1,98	0,77	0	benign	0,11	neutral	0,59	neutral	2,48	neutral	-0,97	deleterious	-2,64	neutral_impact	0,34	neutral	0,65	neutral	0,71	deleterious	2,07	16,65	0,26	0,45	neutral	0,18	neutral	0,19	neutral	0,26	neutral	0,33	3	neutral	0,31	deleterious	0,74	neutral	-6	neutral	0,17	medium_impact	0,01	medium_impact	0,28	medium_impact	-0,88	0,47	0,8	63,98	10,92	N	0,34	N	0,07	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9766	9766	C	A	MI.7822	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	560	187	T	N	aCc/aAc	1,98	0,77	0	possibly_damaging	0,64	neutral	0,41	neutral	2,39	neutral	-1,69	deleterious	-3,62	medium_impact	2,52	neutral	0,61	neutral	0,56	deleterious	3,74	23,3	0,33	0,5	neutral	0,39	disease	0,71	neutral	0,36	disease	0,51	0	neutral	0,66	neutral	0,39	NA	0	deleterious	0,51	low_impact	-1,11	medium_impact	0,1	medium_impact	1,08	0,59	0,8	63,98	10,92	N	0,36	N	0,52	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9766	9766	C	T	MI.7823	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	560	187	T	I	aCc/aTc	1,98	0,77	0	possibly_damaging	0,59	neutral	0,46	neutral	2,38	deleterious	-3,15	deleterious	-4,98	high_impact	4,05	neutral	0,63	neutral	0,56	deleterious	4,04	23,7	0,13	0,4	neutral	0,27	disease	0,72	disease	0,59	disease	0,66	3	neutral	0,59	neutral	0,44	deleterious	1	deleterious	0,53	low_impact	-1,02	medium_impact	0,15	high_impact	2,45	0,49	0,8	63,98	10,92	N	0,43	N	0,9	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9768	9768	A	C	MI.7824	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	562	188	I	L	Att/Ctt	-5,89	0	0	probably_damaging	0,91	neutral	0,66	neutral	2,14	neutral	-0,71	neutral	-1,7	low_impact	1,34	damaging	0,51	damaging	0,13	deleterious	3,89	23,5	0,22	0,45	neutral	0,16	disease	0,59	neutral	0,38	neutral	0,41	2	neutral	0,89	neutral	0,38	neutral	-2	deleterious	0,49	low_impact	-1,85	medium_impact	0,36	medium_impact	0,02	0,59	0,8	75,48	11,41	N	0,26	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	COSM1155708	.	.	.	.	.	.	.	.
chrM	9768	9768	A	T	MI.7825	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	562	188	I	F	Att/Ttt	-5,89	0	0	probably_damaging	0,98	neutral	0,71	neutral	1,9	neutral	-2,65	deleterious	-3,69	low_impact	1,57	damaging	0,53	damaging	0,11	deleterious	4,18	23,8	0,13	0,4	neutral	0,48	disease	0,63	neutral	0,41	neutral	0,45	1	deleterious	0,98	neutral	0,37	neutral	-2	deleterious	0,75	low_impact	-2,51	medium_impact	0,41	medium_impact	0,22	0,61	0,8	75,48	11,41	N	0,22	N	0,94	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9768	9768	A	G	MI.7826	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	562	188	I	V	Att/Gtt	-5,89	0	0	possibly_damaging	0,79	neutral	0,51	neutral	2,01	neutral	-1,51	neutral	-0,94	medium_impact	3,19	damaging	0,59	damaging	0,18	deleterious	3,19	22,7	0,37	0,5	neutral	0,25	neutral	0,45	disease	0,58	neutral	0,45	1	neutral	0,76	neutral	0,36	NA	0	deleterious	0,46	low_impact	-1,43	medium_impact	0,2	medium_impact	1,68	0,37	0,8	75,48	11,41	N	0,34	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9769	9769	T	C	MI.7827	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	563	188	I	T	aTt/aCt	6,84	1	0	probably_damaging	0,99	neutral	0,44	neutral	1,85	deleterious	-3,68	deleterious	-4,66	high_impact	3,88	damaging	0,59	damaging	0,01	deleterious	3,4	23	0,04	0,35	neutral	0,47	disease	0,73	disease	0,68	disease	0,67	3	deleterious	0,99	neutral	0,23	deleterious	2	deleterious	0,78	low_impact	-2,81	medium_impact	0,13	high_impact	2,3	0,22	0,8	75,48	11,41	N	0,48	N	0,91	polymorphism	1	0,15	.	.	.	.	.	.	COSM1138442	.	.	.	.	.	.	.	.
chrM	9769	9769	T	A	MI.7828	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	563	188	I	N	aTt/aAt	6,84	1	0	probably_damaging	1	neutral	0,34	neutral	1,82	deleterious	-5,29	deleterious	-6,57	high_impact	3,68	neutral	0,63	damaging	0,02	deleterious	4,47	24,2	0,05	0,35	disease	0,69	disease	0,85	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	0,03	high_impact	2,12	0,15	0,8	75,48	11,41	N	0,47	N	0,97	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9769	9769	T	G	MI.7829	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	563	188	I	S	aTt/aGt	6,84	1	0	probably_damaging	0,99	neutral	0,46	neutral	1,84	deleterious	-4,28	deleterious	-5,6	high_impact	3,68	neutral	0,65	damaging	0,05	deleterious	4,36	24,1	0,02	0,35	disease	0,54	disease	0,85	disease	0,68	disease	0,73	5	deleterious	0,99	neutral	0,24	deleterious	2	deleterious	0,83	low_impact	-2,81	medium_impact	0,15	high_impact	2,12	0,17	0,8	75,48	11,41	N	0,47	N	0,93	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8894	8894	A	T	MI.783	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	368	123	N	I	aAt/aTt	-2,42	0	0,02	benign	0,01	neutral	0,24	neutral	3,95	neutral	1,02	neutral	-0,18	neutral_impact	-0,18	neutral	0,87	neutral	0,94	deleterious	0,05	3,12	0,48	0,65	disease	0,64	neutral	0,43	neutral	0,21	disease	0,59	2	neutral	0,76	deleterious	0,62	neutral	-6	neutral	0,17	medium_impact	1,14	medium_impact	0,01	low_impact	-1,25	0,35	0,9	24,34	21,11	N	0,39	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9770	9770	T	G	MI.7830	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	564	188	I	M	atT/atG	5,68	1	0,01	probably_damaging	0,99	neutral	0,23	neutral	1,89	neutral	-2,75	deleterious	-2,61	low_impact	1,47	damaging	0,54	damaging	0,09	deleterious	3,54	23,1	0,21	0,45	neutral	0,26	neutral	0,43	neutral	0,36	neutral	0,4	2	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,68	low_impact	-2,81	medium_impact	-0,11	medium_impact	0,14	0,49	0,8	75,48	11,41	N	0,49	N	0,66	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9770	9770	T	A	MI.7831	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	564	188	I	M	atT/atA	5,68	1	0,01	probably_damaging	0,99	neutral	0,23	neutral	1,89	neutral	-2,75	deleterious	-2,61	low_impact	1,47	damaging	0,54	damaging	0,09	deleterious	3,75	23,3	0,21	0,45	neutral	0,26	neutral	0,43	neutral	0,36	neutral	0,4	2	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,68	low_impact	-2,81	medium_impact	-0,11	medium_impact	0,14	0,49	0,8	75,48	11,41	P	0,49	N	0,66	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9771	9771	T	C	MI.7832	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	565	189	S	P	Tcc/Ccc	-4,04	0	0	probably_damaging	0,99	neutral	0,2	neutral	1,97	deleterious	-3,7	deleterious	-3,22	medium_impact	2,04	damaging	0,48	damaging	0,05	deleterious	4,07	23,7	0,05	0,35	neutral	0,47	disease	0,86	disease	0,69	disease	0,69	4	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,8	low_impact	-2,81	medium_impact	-0,15	medium_impact	0,65	0,09	0,8	74,33	11,3	N	0,27	N	0,98	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9771	9771	T	A	MI.7833	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	565	189	S	T	Tcc/Acc	-4,04	0	0	probably_damaging	0,92	neutral	0,4	neutral	2,03	neutral	-2,24	neutral	-1,74	low_impact	1,1	neutral	0,62	damaging	0,14	deleterious	3,86	23,5	0,25	0,45	neutral	0,22	disease	0,52	neutral	0,38	neutral	0,45	1	neutral	0,92	neutral	0,24	neutral	-2	deleterious	0,55	low_impact	-1,9	medium_impact	0,09	medium_impact	-0,2	0,5	0,8	74,33	11,3	N	0,28	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9771	9771	T	G	MI.7834	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	565	189	S	A	Tcc/Gcc	-4,04	0	0	probably_damaging	0,96	neutral	0,53	neutral	2,25	neutral	-0,33	neutral	0,22	neutral_impact	-0,08	neutral	0,7	neutral	0,78	neutral	1,08	11,11	0,28	0,45	neutral	0,19	neutral	0,09	neutral	0,28	neutral	0,23	5	neutral	0,95	neutral	0,29	neutral	-2	deleterious	0,44	low_impact	-2,21	medium_impact	0,22	low_impact	-1,25	0,24	0,8	74,33	11,3	N	0,36	N	0,4	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9772	9772	C	A	MI.7835	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	566	189	S	Y	tCc/tAc	1,05	0,87	0	probably_damaging	1	neutral	1	neutral	1,95	deleterious	-4,6	deleterious	-4,19	medium_impact	3,16	damaging	0,55	damaging	0,06	deleterious	4,15	23,8	0,06	0,35	disease	0,54	disease	0,83	disease	0,71	disease	0,76	5	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,79	low_impact	-3,78	high_impact	1,9	medium_impact	1,65	0,14	0,8	74,33	11,3	N	0,27	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9772	9772	C	G	MI.7836	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	566	189	S	C	tCc/tGc	1,05	0,87	0	probably_damaging	1	neutral	0,17	neutral	1,95	deleterious	-4,53	deleterious	-2,71	medium_impact	3,16	damaging	0,57	damaging	0,06	deleterious	3,69	23,3	0,06	0,35	disease	0,72	disease	0,83	disease	0,58	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,79	low_impact	-3,78	medium_impact	-0,2	medium_impact	1,65	0,2	0,8	74,33	11,3	N	0,27	N	0,98	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9772	9772	C	T	MI.7837	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	566	189	S	F	tCc/tTc	1,05	0,87	0	probably_damaging	1	neutral	0,71	neutral	1,95	deleterious	-4,5	deleterious	-4,19	medium_impact	3,16	damaging	0,52	damaging	0,06	deleterious	4,37	24,1	0,07	0,35	disease	0,59	disease	0,86	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,36	deleterious	1	deleterious	0,8	low_impact	-3,78	medium_impact	0,41	medium_impact	1,65	0,04	0,8	74,33	11,3	N	0,28	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9774	9774	G	T	MI.7838	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	568	190	D	Y	Gac/Tac	-13,98	0	0	probably_damaging	1	neutral	0,44	neutral	1,26	deleterious	-6,83	deleterious	-8,63	high_impact	4,51	neutral	0,62	damaging	0,01	deleterious	4,01	23,6	0,03	0,35	disease	0,61	disease	0,94	disease	0,78	disease	0,87	7	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	0,13	high_impact	2,86	0,04	0,8	73,95	11,69	N	0,43	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9774	9774	G	C	MI.7839	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	568	190	D	H	Gac/Cac	-13,98	0	0	probably_damaging	1	neutral	0,28	neutral	1,27	deleterious	-6,1	deleterious	-6,7	high_impact	3,62	damaging	0,57	damaging	0,01	deleterious	3,77	23,4	0,08	0,35	disease	0,51	disease	0,88	disease	0,78	disease	0,77	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,04	high_impact	2,06	0,28	0,8	73,95	11,69	N	0,33	N	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8894	8894	A	C	MI.784	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	368	123	N	T	aAt/aCt	-2,42	0	0,02	benign	0,11	neutral	0,59	neutral	3,93	neutral	0,59	neutral	0,39	neutral_impact	0,07	neutral	0,87	neutral	0,97	neutral	-0,39	0,41	0,64	0,7	neutral	0,43	neutral	0,25	neutral	0,17	neutral	0,45	1	neutral	0,31	deleterious	0,74	neutral	-6	neutral	0,22	medium_impact	0,11	medium_impact	0,38	low_impact	-1,04	0,5	0,9	24,34	21,11	N	0,37	N	0,16	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9774	9774	G	A	MI.7840	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	568	190	D	N	Gac/Aac	-13,98	0	0	probably_damaging	1	neutral	0,54	neutral	1,32	deleterious	-4,5	deleterious	-4,79	medium_impact	3,27	damaging	0,53	damaging	0,03	deleterious	4,32	24	0,53	0,6	neutral	0,34	disease	0,85	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,8	low_impact	-3,78	medium_impact	0,23	medium_impact	1,75	0,69	0,85	73,95	11,69	N	0,25	N	0,96	polymorphism	1	0,11	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	9775	9775	A	C	MI.7841	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	569	190	D	A	gAc/gCc	9,15	1	0	probably_damaging	1	neutral	0,91	neutral	1,31	deleterious	-4,76	deleterious	-7,67	medium_impact	2,94	damaging	0,59	damaging	0,02	deleterious	3,86	23,5	0,08	0,35	neutral	0,25	disease	0,85	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,46	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	0,76	medium_impact	1,45	0,15	0,8	73,95	11,69	N	0,39	N	0,83	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9775	9775	A	G	MI.7842	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	569	190	D	G	gAc/gGc	9,15	1	0	probably_damaging	1	neutral	0,45	neutral	1,3	deleterious	-4,99	deleterious	-6,72	medium_impact	2,63	damaging	0,6	damaging	0,01	deleterious	4,21	23,9	0,08	0,35	neutral	0,44	disease	0,83	disease	0,7	disease	0,55	1	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,79	low_impact	-3,78	medium_impact	0,14	medium_impact	1,17	0,12	0,8	73,95	11,69	N	0,41	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9775	9775	A	T	MI.7843	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	569	190	D	V	gAc/gTc	9,15	1	0	probably_damaging	1	neutral	0,46	neutral	1,27	deleterious	-5,97	deleterious	-8,63	high_impact	3,7	damaging	0,56	damaging	0,01	deleterious	4	23,6	0,03	0,35	neutral	0,45	disease	0,94	disease	0,75	disease	0,85	7	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	0,15	high_impact	2,13	0,03	0,8	73,95	11,69	N	0,48	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9776	9776	C	G	MI.7844	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	570	190	D	E	gaC/gaG	8,69	1	0	probably_damaging	0,99	neutral	1	neutral	1,37	deleterious	-3,63	deleterious	-3,8	medium_impact	3,04	damaging	0,6	damaging	0,03	deleterious	3,95	23,6	0,25	0,45	neutral	0,23	disease	0,79	disease	0,61	disease	0,51	0	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,76	low_impact	-2,81	high_impact	1,9	medium_impact	1,54	0,38	0,8	73,95	11,69	N	0,41	N	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9776	9776	C	A	MI.7845	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	570	190	D	E	gaC/gaA	8,69	1	0	probably_damaging	0,99	neutral	1	neutral	1,37	deleterious	-3,63	deleterious	-3,8	medium_impact	3,04	damaging	0,6	damaging	0,03	deleterious	4,29	24	0,25	0,45	neutral	0,23	disease	0,79	disease	0,61	disease	0,51	0	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,76	low_impact	-2,81	high_impact	1,9	medium_impact	1,54	0,38	0,8	73,95	11,69	N	0,41	N	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9777	9777	G	A	MI.7846	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	571	191	G	S	Ggc/Agc	-6,58	0	0	probably_damaging	1	neutral	0,43	neutral	2,7	neutral	0,59	neutral	1,27	neutral_impact	-0,25	neutral	0,62	neutral	0,66	deleterious	1,91	15,67	0,14	0,4	neutral	0,1	neutral	0,11	neutral	0,25	neutral	0,25	5	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,66	low_impact	-3,78	medium_impact	0,12	low_impact	-1,41	0,52	0,8	73,95	11,23	N	0,38	N	0,85	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9777	9777	G	T	MI.7847	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	571	191	G	C	Ggc/Tgc	-6,58	0	0	probably_damaging	1	neutral	0,17	neutral	2,34	deleterious	-4,81	neutral	-2,06	high_impact	3,9	neutral	0,62	damaging	0,19	deleterious	4,21	23,9	0,04	0,35	disease	0,65	disease	0,87	disease	0,6	disease	0,76	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,2	high_impact	2,31	0,21	0,8	73,95	11,23	N	0,32	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9777	9777	G	C	MI.7848	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	571	191	G	R	Ggc/Cgc	-6,58	0	0	probably_damaging	1	neutral	0,33	neutral	2,39	neutral	-2,28	neutral	-2,27	high_impact	3,55	damaging	0,58	damaging	0,19	deleterious	4,1	23,7	0,03	0,35	neutral	0,27	disease	0,86	disease	0,81	disease	0,77	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	0,02	medium_impact	2	0,44	0,8	73,95	11,23	N	0,38	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9778	9778	G	C	MI.7849	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	572	191	G	A	gGc/gCc	1,98	0,98	0	probably_damaging	1	neutral	0,54	neutral	2,4	neutral	-1,86	neutral	-0,12	medium_impact	2,45	neutral	0,66	neutral	0,7	neutral	1,74	14,65	0,13	0,4	neutral	0,14	neutral	0,45	neutral	0,37	neutral	0,44	1	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,69	low_impact	-3,78	medium_impact	0,23	medium_impact	1,01	0,46	0,8	73,95	11,23	N	0,49	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8895	8895	T	G	MI.785	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	369	123	N	K	aaT/aaG	-3,34	0	0	benign	0,16	neutral	1	neutral	3,93	neutral	0,61	neutral	-0,31	neutral_impact	-0,62	neutral	0,94	neutral	0,79	deleterious	0,53	7,62	0,79	0,85	neutral	0,3	disease	0,51	neutral	0,19	neutral	0,34	3	neutral	0,16	deleterious	0,92	neutral	-6	neutral	0,3	medium_impact	-0,07	high_impact	1,98	low_impact	-1,63	0,59	0,9	24,34	21,11	N	0,31	N	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9778	9778	G	T	MI.7850	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	572	191	G	V	gGc/gTc	1,98	0,98	0	probably_damaging	1	neutral	0,52	neutral	2,34	deleterious	-4,57	deleterious	-2,94	high_impact	3,55	damaging	0,59	damaging	0,25	deleterious	3,9	23,5	0,03	0,35	neutral	0,32	disease	0,79	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,77	low_impact	-3,78	medium_impact	0,21	medium_impact	2	0,13	0,8	73,95	11,23	N	0,42	N	0,97	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9778	9778	G	A	MI.7851	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	572	191	G	D	gGc/gAc	1,98	0,98	0	probably_damaging	1	neutral	0,28	neutral	2,44	neutral	-1,23	neutral	-1,6	medium_impact	2,75	neutral	0,6	damaging	0,23	deleterious	3,91	23,5	0,04	0,35	neutral	0,22	disease	0,81	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,76	low_impact	-3,78	medium_impact	-0,04	medium_impact	1,28	0,14	0,8	73,95	11,23	P	0,48	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9780	9780	A	G	MI.7852	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	574	192	I	V	Atc/Gtc	-12,13	0	0	possibly_damaging	0,9	neutral	0,52	neutral	2,57	neutral	0,88	neutral	0,47	neutral_impact	-0,78	neutral	0,74	neutral	0,98	neutral	-1,4	0	0,6	0,65	neutral	0,11	neutral	0,05	neutral	0,23	neutral	0,23	5	neutral	0,89	neutral	0,31	neutral	-3	deleterious	0,5	low_impact	-1,8	medium_impact	0,21	low_impact	-1,88	0,4	0,8	14,56	21,19	N	0,4	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9780	9780	A	C	MI.7853	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	574	192	I	L	Atc/Ctc	-12,13	0	0	possibly_damaging	0,9	neutral	0,62	neutral	2,12	neutral	-1,27	neutral	-1,34	low_impact	1,38	neutral	0,64	damaging	0,1	deleterious	2,21	17,58	0,2	0,45	neutral	0,16	disease	0,56	disease	0,62	disease	0,62	2	neutral	0,88	neutral	0,36	neutral	-3	deleterious	0,56	low_impact	-1,8	medium_impact	0,31	medium_impact	0,05	0,73	0,85	14,56	21,19	N	0,2	N	0,47	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9780	9780	A	T	MI.7854	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	574	192	I	F	Atc/Ttc	-12,13	0	0	probably_damaging	0,98	neutral	0,68	neutral	2	deleterious	-3,41	deleterious	-2,96	medium_impact	3,4	damaging	0,6	damaging	0,11	deleterious	3,88	23,5	0,11	0,4	neutral	0,34	disease	0,78	disease	0,68	disease	0,73	5	neutral	0,98	neutral	0,35	deleterious	1	deleterious	0,72	low_impact	-2,51	medium_impact	0,38	medium_impact	1,86	0,64	0,8	14,56	21,19	N	0,22	N	0,9	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9781	9781	T	C	MI.7855	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	575	192	I	T	aTc/aCc	-0,1	0,01	0	probably_damaging	0,98	neutral	0,39	neutral	2,02	neutral	-2,86	neutral	-1,89	low_impact	1,56	neutral	0,64	neutral	0,37	deleterious	2,08	16,74	0,06	0,35	neutral	0,28	disease	0,57	disease	0,57	neutral	0,5	0	deleterious	0,98	neutral	0,21	neutral	-2	deleterious	0,69	low_impact	-2,51	medium_impact	0,08	medium_impact	0,22	0,26	0,8	14,56	21,19	N	0,33	N	0,93	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9781	9781	T	A	MI.7856	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	575	192	I	N	aTc/aAc	-0,1	0,01	0	probably_damaging	1	neutral	0,3	neutral	1,98	deleterious	-4,47	deleterious	-4,41	medium_impact	2,51	neutral	0,62	damaging	0,1	deleterious	4,5	24,3	0,06	0,35	neutral	0,49	disease	0,84	disease	0,68	disease	0,76	5	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,78	low_impact	-3,78	medium_impact	-0,02	medium_impact	1,07	0,22	0,8	14,56	21,19	N	0,24	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9781	9781	T	G	MI.7857	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	575	192	I	S	aTc/aGc	-0,1	0,01	0	probably_damaging	0,98	neutral	0,45	neutral	2	deleterious	-3,42	deleterious	-3	low_impact	1,47	neutral	0,63	damaging	0,27	deleterious	4,31	24	0,02	0,35	neutral	0,33	disease	0,78	disease	0,58	disease	0,55	1	deleterious	0,98	neutral	0,24	neutral	-2	deleterious	0,73	low_impact	-2,51	medium_impact	0,14	medium_impact	0,14	0,2	0,8	14,56	21,19	N	0,25	N	0,91	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9782	9782	C	A	MI.7858	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	576	192	I	M	atC/atA	4,52	0,69	0	probably_damaging	0,99	neutral	0,21	neutral	2,01	deleterious	-3,15	neutral	-1,56	medium_impact	2,86	neutral	0,63	damaging	0,1	deleterious	3,89	23,5	0,21	0,45	neutral	0,21	disease	0,51	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,66	low_impact	-2,81	medium_impact	-0,14	medium_impact	1,38	0,73	0,85	14,56	21,19	N	0,34	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9782	9782	C	G	MI.7859	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	576	192	I	M	atC/atG	4,52	0,69	0	probably_damaging	0,99	neutral	0,21	neutral	2,01	deleterious	-3,15	neutral	-1,56	medium_impact	2,86	neutral	0,63	damaging	0,1	deleterious	3,45	23	0,21	0,45	neutral	0,21	disease	0,51	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,66	low_impact	-2,81	medium_impact	-0,14	medium_impact	1,38	0,73	0,85	14,56	21,19	N	0,38	N	0,61	polymorphism	1	0,03	rs28433045	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8895	8895	T	A	MI.786	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	369	123	N	K	aaT/aaA	-3,34	0	0	benign	0,16	neutral	1	neutral	3,93	neutral	0,61	neutral	-0,31	neutral_impact	-0,62	neutral	0,94	neutral	0,79	deleterious	0,82	9,58	0,79	0,85	neutral	0,3	disease	0,51	neutral	0,19	neutral	0,34	3	neutral	0,16	deleterious	0,92	neutral	-6	neutral	0,3	medium_impact	-0,07	high_impact	1,98	low_impact	-1,63	0,59	0,9	24,34	21,11	N	0,31	N	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9783	9783	T	G	MI.7860	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	577	193	Y	D	Tac/Gac	-14,68	0	0	probably_damaging	1	neutral	0,2	neutral	1,57	deleterious	-6,21	deleterious	-9,45	high_impact	4,61	neutral	0,61	damaging	0,01	deleterious	4,04	23,7	0,02	0,35	disease	0,79	disease	0,86	disease	0,84	disease	0,84	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	-0,15	high_impact	2,95	0,13	0,8	74,33	11,58	N	0,48	N	0,99	disease_causing	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9783	9783	T	C	MI.7861	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	577	193	Y	H	Tac/Cac	-14,68	0	0	probably_damaging	1	neutral	0,52	neutral	1,6	deleterious	-4,51	deleterious	-4,75	high_impact	3,92	damaging	0,57	damaging	0,03	deleterious	3,68	23,3	0,1	0,4	disease	0,62	disease	0,79	disease	0,84	disease	0,8	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	0,21	high_impact	2,33	0,22	0,8	74,33	11,58	N	0,3	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9783	9783	T	A	MI.7862	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	577	193	Y	N	Tac/Aac	-14,68	0	0	probably_damaging	1	neutral	0,29	neutral	1,58	deleterious	-5,41	deleterious	-8,52	high_impact	4,26	damaging	0,59	damaging	0,01	deleterious	4,11	23,7	0,03	0,35	disease	0,7	disease	0,85	disease	0,78	disease	0,78	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,03	high_impact	2,64	0,11	0,8	74,33	11,58	N	0,39	N	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9784	9784	A	G	MI.7863	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	578	193	Y	C	tAc/tGc	7,53	1	0	probably_damaging	1	neutral	0,18	neutral	1,56	deleterious	-6,64	deleterious	-8,49	high_impact	3,8	neutral	0,63	damaging	0,02	deleterious	3,66	23,2	0,03	0,35	disease	0,79	disease	0,89	disease	0,8	disease	0,83	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	-0,18	high_impact	2,22	0,13	0,8	74,33	11,58	P	0,52	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9784	9784	A	C	MI.7864	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	578	193	Y	S	tAc/tCc	7,53	1	0	probably_damaging	1	neutral	0,42	neutral	1,59	deleterious	-4,98	deleterious	-8,49	high_impact	4,61	neutral	0,61	damaging	0,02	deleterious	3,84	23,4	0,04	0,35	disease	0,59	disease	0,85	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	0,11	high_impact	2,95	0,15	0,8	74,33	11,58	P	0,57	P	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9784	9784	A	T	MI.7865	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	578	193	Y	F	tAc/tTc	7,53	1	0	probably_damaging	0,99	neutral	0,68	neutral	1,89	neutral	-1,42	deleterious	-3,62	low_impact	1,69	damaging	0,56	damaging	0,08	deleterious	3,53	23,1	0,24	0,45	neutral	0,16	disease	0,64	disease	0,54	neutral	0,42	2	deleterious	0,99	neutral	0,35	neutral	-2	deleterious	0,74	low_impact	-2,81	medium_impact	0,38	medium_impact	0,33	0,5	0,8	74,33	11,58	N	0,44	N	0,72	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9786	9786	G	T	MI.7866	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	580	194	G	C	Ggc/Tgc	-6,81	0	0	probably_damaging	1	neutral	0,17	neutral	0,89	deleterious	-7,58	deleterious	-8,61	high_impact	4,72	damaging	0,55	damaging	0,01	deleterious	4,27	24	0,03	0,35	disease	0,77	disease	0,92	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,78	medium_impact	-0,2	high_impact	3,05	0,28	0,8	73,18	11,8	N	0,5	N	0,98	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9786	9786	G	C	MI.7867	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	580	194	G	R	Ggc/Cgc	-6,81	0	0	probably_damaging	1	neutral	0,33	neutral	0,9	deleterious	-6,58	deleterious	-7,65	high_impact	4,72	neutral	0,62	damaging	0,02	deleterious	4,12	23,8	0,03	0,35	disease	0,6	disease	0,91	disease	0,84	disease	0,85	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,88	low_impact	-3,78	medium_impact	0,02	high_impact	3,05	0,51	0,8	73,18	11,8	P	0,55	P	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9786	9786	G	A	MI.7868	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	580	194	G	S	Ggc/Agc	-6,81	0	0	probably_damaging	1	neutral	0,43	neutral	0,94	deleterious	-5,26	deleterious	-5,74	medium_impact	3,08	damaging	0,55	damaging	0,03	deleterious	4,38	24,1	0,06	0,35	neutral	0,5	disease	0,81	disease	0,65	disease	0,52	0	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,84	low_impact	-3,78	medium_impact	0,12	medium_impact	1,58	0,58	0,8	73,18	11,8	N	0,18	N	0,85	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9787	9787	G	C	MI.7869	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	581	194	G	A	gGc/gCc	7,3	1	0	probably_damaging	1	neutral	0,48	neutral	0,95	deleterious	-4,99	deleterious	-5,74	medium_impact	2,89	damaging	0,55	damaging	0,02	deleterious	3,25	22,8	0,08	0,35	neutral	0,44	disease	0,69	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,79	low_impact	-3,78	medium_impact	0,17	medium_impact	1,41	0,52	0,8	73,18	11,8	N	0,43	N	0,3	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8896	8896	G	A	MI.787	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	370	124	A	T	Gcc/Acc	-6,12	0	0	benign	0	neutral	0,39	neutral	3,89	neutral	-1	neutral	-0,66	low_impact	1,29	neutral	0,91	neutral	0,77	neutral	1,16	11,55	0,48	0,65	disease	0,55	disease	0,55	neutral	0,25	neutral	0,28	4	neutral	0,61	deleterious	0,7	neutral	-6	neutral	0,2	high_impact	2,09	medium_impact	0,18	medium_impact	0,01	0,8	0,9	19,91	7,92	N	0,36	N	0,06	polymorphism	1	0,01	rs202120082	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9787	9787	G	T	MI.7870	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	581	194	G	V	gGc/gTc	7,3	1	0	probably_damaging	1	neutral	0,5	neutral	0,9	deleterious	-6,37	deleterious	-8,61	high_impact	4,72	damaging	0,52	damaging	0,01	deleterious	3,9	23,5	0,03	0,35	neutral	0,42	disease	0,9	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	0,19	high_impact	3,05	0,16	0,8	73,18	11,8	P	0,54	P	0,97	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9787	9787	G	A	MI.7871	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	581	194	G	D	gGc/gAc	7,3	1	0	probably_damaging	1	neutral	0,2	neutral	0,91	deleterious	-6,07	deleterious	-6,7	high_impact	4,17	damaging	0,48	damaging	0,01	deleterious	3,92	23,5	0,03	0,35	disease	0,68	disease	0,88	disease	0,83	disease	0,84	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	-0,15	high_impact	2,55	0,23	0,8	73,18	11,8	P	0,6	P	0,98	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9789	9789	T	C	MI.7872	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	583	195	S	P	Tca/Cca	-3,11	0	0	probably_damaging	0,99	neutral	0,17	neutral	1,76	deleterious	-4,41	deleterious	-4,58	high_impact	4,12	damaging	0,49	damaging	0,04	deleterious	4,12	23,8	0,02	0,35	disease	0,68	disease	0,87	disease	0,81	disease	0,81	6	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-2,81	medium_impact	-0,2	high_impact	2,51	0,35	0,8	73,56	11,73	N	0,5	N	0,98	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	T9789C	Myopathy	-	+	Reported	1
chrM	9789	9789	T	A	MI.7873	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	583	195	S	T	Tca/Aca	-3,11	0	0	probably_damaging	0,92	neutral	0,58	neutral	1,86	neutral	-2,35	neutral	-2,48	low_impact	1,56	damaging	0,58	damaging	0,26	deleterious	2,8	21,3	0,13	0,4	neutral	0,23	disease	0,56	neutral	0,44	neutral	0,42	2	neutral	0,91	neutral	0,33	neutral	-2	deleterious	0,66	low_impact	-1,9	medium_impact	0,27	medium_impact	0,22	0,73	0,85	73,56	11,73	N	0,24	N	0,63	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9789	9789	T	G	MI.7874	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	583	195	S	A	Tca/Gca	-3,11	0	0	probably_damaging	0,96	neutral	0,43	neutral	1,91	neutral	-1,88	deleterious	-2,69	low_impact	1,94	damaging	0,59	neutral	0,34	deleterious	2,78	21,3	0,11	0,4	neutral	0,31	neutral	0,44	neutral	0,47	neutral	0,4	2	neutral	0,95	neutral	0,24	neutral	-2	deleterious	0,6	low_impact	-2,21	medium_impact	0,12	medium_impact	0,56	0,48	0,8	73,56	11,73	N	0,3	N	0,4	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9790	9790	C	T	MI.7875	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	584	195	S	L	tCa/tTa	5,68	1	0	probably_damaging	0,99	neutral	0,57	neutral	1,77	deleterious	-3,95	deleterious	-5,47	high_impact	4,46	damaging	0,49	damaging	0,03	deleterious	4,76	24,7	0,02	0,35	disease	0,67	disease	0,89	disease	0,68	disease	0,74	5	deleterious	0,99	neutral	0,29	deleterious	2	deleterious	0,83	low_impact	-2,81	medium_impact	0,26	high_impact	2,81	0,39	0,8	73,56	11,73	P	0,57	P	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9790	9790	C	G	MI.7876	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	584	195	S	W	tCa/tGa	5,68	1	0	probably_damaging	1	neutral	0,2	neutral	1,73	deleterious	-7,26	deleterious	-6,44	high_impact	4,46	damaging	0,53	damaging	0,03	deleterious	4,46	24,2	0,03	0,35	disease	0,94	disease	0,91	disease	0,76	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	-0,15	high_impact	2,81	0,15	0,8	73,56	11,73	P	0,54	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9792	9792	A	G	MI.7877	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	586	196	T	A	Aca/Gca	-6,35	0	0	probably_damaging	0,98	neutral	0,54	neutral	2,23	neutral	-0,68	deleterious	-3,86	medium_impact	2,14	neutral	0,68	neutral	0,67	deleterious	3,59	23,2	0,16	0,45	neutral	0,16	disease	0,6	neutral	0,44	neutral	0,43	1	neutral	0,97	neutral	0,28	deleterious	1	deleterious	0,67	low_impact	-2,51	medium_impact	0,23	medium_impact	0,74	0,37	0,8	74,71	11,64	N	0,29	N	0,44	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9792	9792	A	C	MI.7878	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	586	196	T	P	Aca/Cca	-6,35	0	0	probably_damaging	1	neutral	0,18	neutral	2,14	deleterious	-3,99	deleterious	-5	high_impact	4,17	neutral	0,63	neutral	0,44	deleterious	3,61	23,2	0,03	0,35	disease	0,5	disease	0,87	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	-0,18	high_impact	2,55	0,31	0,8	74,71	11,64	N	0,47	N	0,98	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9792	9792	A	T	MI.7879	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	586	196	T	S	Aca/Tca	-6,35	0	0	probably_damaging	0,98	neutral	0,66	neutral	2,21	neutral	-1,44	deleterious	-3,08	low_impact	1,59	damaging	0,59	neutral	0,71	deleterious	2,41	18,9	0,23	0,45	neutral	0,24	disease	0,56	neutral	0,39	neutral	0,44	1	neutral	0,97	neutral	0,34	neutral	-2	deleterious	0,7	low_impact	-2,51	medium_impact	0,36	medium_impact	0,24	0,58	0,8	74,71	11,64	N	0,31	N	0,77	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8896	8896	G	C	MI.788	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	370	124	A	P	Gcc/Ccc	-6,12	0	0	benign	0,27	neutral	0,18	neutral	3,84	neutral	-2,18	deleterious	-2,57	medium_impact	3,21	neutral	0,69	neutral	0,39	deleterious	2,16	17,26	0,14	0,65	disease	0,79	disease	0,91	disease	0,73	disease	0,75	5	neutral	0,79	neutral	0,46	neutral	-3	deleterious	0,57	medium_impact	-0,35	medium_impact	-0,08	medium_impact	1,65	0,81	0,9	19,91	7,92	N	0,32	N	0,46	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9793	9793	C	T	MI.7880	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	587	196	T	M	aCa/aTa	6,84	1	0	probably_damaging	1	neutral	0,23	neutral	2,17	neutral	-2,34	deleterious	-4,57	medium_impact	2,67	neutral	0,66	neutral	0,55	deleterious	4,1	23,7	0,05	0,35	neutral	0,32	disease	0,76	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,7	low_impact	-3,78	medium_impact	-0,11	medium_impact	1,21	0,6	0,8	74,71	11,64	N	0,49	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9793	9793	C	A	MI.7881	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	587	196	T	K	aCa/aAa	6,84	1	0	probably_damaging	1	neutral	0,26	neutral	2,17	deleterious	-3,09	deleterious	-4,91	high_impact	4,17	neutral	0,65	neutral	0,41	deleterious	4,7	24,6	0,04	0,35	neutral	0,35	disease	0,88	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,07	high_impact	2,55	0,49	0,8	74,71	11,64	P	0,62	P	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9795	9795	T	C	MI.7882	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	589	197	F	L	Ttt/Ctt	-5,66	0	0	probably_damaging	0,98	neutral	0,39	neutral	1,55	deleterious	-4	deleterious	-5,71	high_impact	4,44	neutral	0,64	damaging	0,03	deleterious	4,13	23,8	0,04	0,35	disease	0,59	disease	0,83	disease	0,74	disease	0,76	5	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-2,51	medium_impact	0,08	high_impact	2,8	0,56	0,8	72,41	11,91	N	0,41	N	0,92	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9795	9795	T	G	MI.7883	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	589	197	F	V	Ttt/Gtt	-5,66	0	0	probably_damaging	1	neutral	0,23	neutral	1,49	deleterious	-5,23	deleterious	-6,67	high_impact	4,79	neutral	0,65	damaging	0,02	deleterious	4,16	23,8	0,04	0,35	disease	0,75	disease	0,9	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	-0,11	high_impact	3,11	0,33	0,8	72,41	11,91	P	0,62	P	0,97	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9795	9795	T	A	MI.7884	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	589	197	F	I	Ttt/Att	-5,66	0	0	probably_damaging	0,99	neutral	0,19	neutral	1,47	deleterious	-6,04	deleterious	-5,71	high_impact	4,79	neutral	0,68	damaging	0,03	deleterious	4,49	24,3	0,05	0,35	disease	0,75	disease	0,86	disease	0,76	disease	0,78	6	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-2,81	medium_impact	-0,17	high_impact	3,11	0,44	0,8	72,41	11,91	P	0,63	P	0,96	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9796	9796	T	G	MI.7885	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	590	197	F	C	tTt/tGt	7,53	1	0	probably_damaging	1	neutral	0,06	neutral	1,48	deleterious	-5,71	deleterious	-7,62	high_impact	4,79	neutral	0,71	damaging	0,02	deleterious	4,21	23,9	0,02	0,35	disease	0,92	disease	0,9	disease	0,79	disease	0,86	7	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,88	low_impact	-3,78	medium_impact	-0,49	high_impact	3,11	0,2	0,8	72,41	11,91	P	0,65	P	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9796	9796	T	C	MI.7886	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	590	197	F	S	tTt/tCt	7,53	1	0	probably_damaging	1	neutral	0,33	neutral	1,47	deleterious	-5,88	deleterious	-7,62	high_impact	4,44	neutral	0,71	damaging	0,02	deleterious	4,41	24,1	0,02	0,35	disease	0,82	disease	0,88	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,78	medium_impact	0,02	high_impact	2,8	0,23	0,8	72,41	11,91	P	0,58	P	0,96	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9796	9796	T	A	MI.7887	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	590	197	F	Y	tTt/tAt	7,53	1	0	probably_damaging	0,98	neutral	0,38	neutral	1,75	neutral	-2,38	deleterious	-2,86	high_impact	3,58	neutral	0,7	damaging	0,03	deleterious	4,57	24,4	0,09	0,35	neutral	0,31	disease	0,84	disease	0,73	disease	0,75	5	deleterious	0,99	neutral	0,2	deleterious	2	deleterious	0,79	low_impact	-2,51	medium_impact	0,07	high_impact	2,03	0,44	0,8	72,41	11,91	P	0,56	P	0,8	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9797	9797	T	A	MI.7888	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	591	197	F	L	ttT/ttA	5,68	1	0	probably_damaging	0,98	neutral	0,39	neutral	1,55	deleterious	-4	deleterious	-5,71	high_impact	4,44	neutral	0,64	damaging	0,03	deleterious	4,53	24,3	0,04	0,35	disease	0,59	disease	0,83	disease	0,74	disease	0,76	5	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-2,51	medium_impact	0,08	high_impact	2,8	0,56	0,8	72,41	11,91	P	0,63	P	0,92	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9797	9797	T	G	MI.7889	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	591	197	F	L	ttT/ttG	5,68	1	0	probably_damaging	0,98	neutral	0,39	neutral	1,55	deleterious	-4	deleterious	-5,71	high_impact	4,44	neutral	0,64	damaging	0,03	deleterious	4,34	24	0,04	0,35	disease	0,59	disease	0,83	disease	0,74	disease	0,76	5	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-2,51	medium_impact	0,08	high_impact	2,8	0,56	0,8	72,41	11,91	P	0,63	P	0,92	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8896	8896	G	T	MI.789	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	370	124	A	S	Gcc/Tcc	-6,12	0	0	benign	0,01	neutral	0,78	neutral	3,91	neutral	-0,14	neutral	1,04	neutral_impact	0,06	neutral	0,86	neutral	0,92	neutral	-0,95	0,02	0,43	0,65	neutral	0,31	neutral	0,21	neutral	0,19	neutral	0,38	2	neutral	0,19	deleterious	0,89	neutral	-6	neutral	0,15	medium_impact	1,14	medium_impact	0,6	low_impact	-1,05	0,8	0,9	19,91	7,92	N	0,34	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9798	9798	T	A	MI.7890	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	592	198	F	I	Ttt/Att	-3,11	0	0	benign	0,3	neutral	0,08	neutral	1,68	deleterious	-6,43	deleterious	-5,58	high_impact	4,17	neutral	0,67	damaging	0,03	deleterious	4,21	23,9	0,05	0,35	disease	0,7	disease	0,84	disease	0,71	disease	0,76	5	neutral	0,91	neutral	0,39	neutral	-2	deleterious	0,57	medium_impact	-0,51	medium_impact	-0,41	high_impact	2,55	0,38	0,8	75,1	11,32	N	0,32	N	0,96	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9798	9798	T	G	MI.7891	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	592	198	F	V	Ttt/Gtt	-3,11	0	0	benign	0,4	neutral	0,22	neutral	1,68	deleterious	-6,78	deleterious	-6,47	high_impact	4,51	neutral	0,63	damaging	0,03	deleterious	3,85	23,4	0,04	0,35	disease	0,69	disease	0,89	disease	0,72	disease	0,78	6	neutral	0,74	neutral	0,41	neutral	-2	deleterious	0,57	medium_impact	-0,7	medium_impact	-0,12	high_impact	2,86	0,34	0,8	75,1	11,32	N	0,37	N	0,97	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9798	9798	T	C	MI.7892	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	592	198	F	L	Ttt/Ctt	-3,11	0	0	benign	0,16	neutral	0,21	neutral	1,7	deleterious	-5,47	deleterious	-5,58	high_impact	4,51	neutral	0,62	damaging	0,03	deleterious	3,64	23,2	0,03	0,35	neutral	0,47	disease	0,81	disease	0,65	disease	0,67	3	neutral	0,76	deleterious	0,53	neutral	-2	neutral	0,39	medium_impact	-0,17	medium_impact	-0,14	high_impact	2,86	0,56	0,8	75,1	11,32	N	0,38	N	0,92	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9799	9799	T	G	MI.7893	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	593	198	F	C	tTt/tGt	5,68	1	0	probably_damaging	0,94	deleterious	0,04	neutral	1,68	deleterious	-7,41	deleterious	-7,42	high_impact	4,51	neutral	0,7	damaging	0,03	deleterious	4,11	23,8	0,02	0,35	disease	0,89	disease	0,9	disease	0,73	disease	0,82	6	deleterious	0,99	neutral	0,05	deleterious	6	deleterious	0,85	low_impact	-2,03	medium_impact	-0,6	high_impact	2,86	0,23	0,8	75,1	11,32	N	0,48	N	0,98	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9799	9799	T	C	MI.7894	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	593	198	F	S	tTt/tCt	5,68	1	0	possibly_damaging	0,69	neutral	0,21	neutral	1,68	deleterious	-6,62	deleterious	-7,42	high_impact	3,7	neutral	0,66	damaging	0,02	deleterious	4,18	23,8	0,02	0,35	disease	0,77	disease	0,85	disease	0,7	disease	0,7	4	neutral	0,83	neutral	0,26	deleterious	1	deleterious	0,73	low_impact	-1,21	medium_impact	-0,14	high_impact	2,13	0,28	0,8	75,1	11,32	N	0,52	P	0,96	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9799	9799	T	A	MI.7895	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	593	198	F	Y	tTt/tAt	5,68	1	0	benign	0,01	neutral	0,23	neutral	2,3	neutral	-0,68	neutral	-2,41	low_impact	1,21	damaging	0,56	damaging	0,14	deleterious	2,2	17,52	0,11	0,4	neutral	0,11	disease	0,58	neutral	0,5	neutral	0,41	2	neutral	0,77	deleterious	0,61	neutral	-6	neutral	0,18	medium_impact	1,07	medium_impact	-0,11	medium_impact	-0,1	0,52	0,8	75,1	11,32	P	0,5	N	0,8	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9800	9800	T	A	MI.7896	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	594	198	F	L	ttT/ttA	7,53	1	0	benign	0,16	neutral	0,21	neutral	1,7	deleterious	-5,47	deleterious	-5,58	high_impact	4,51	neutral	0,62	damaging	0,03	deleterious	4,16	23,8	0,03	0,35	neutral	0,47	disease	0,81	disease	0,65	disease	0,67	3	neutral	0,76	deleterious	0,53	neutral	-2	neutral	0,39	medium_impact	-0,17	medium_impact	-0,14	high_impact	2,86	0,56	0,8	75,1	11,32	P	0,53	P	0,92	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9800	9800	T	G	MI.7897	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	594	198	F	L	ttT/ttG	7,53	1	0	benign	0,16	neutral	0,21	neutral	1,7	deleterious	-5,47	deleterious	-5,58	high_impact	4,51	neutral	0,62	damaging	0,03	deleterious	4,06	23,7	0,03	0,35	neutral	0,47	disease	0,81	disease	0,65	disease	0,67	3	neutral	0,76	deleterious	0,53	neutral	-2	neutral	0,39	medium_impact	-0,17	medium_impact	-0,14	high_impact	2,86	0,56	0,8	75,1	11,32	P	0,53	P	0,92	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9801	9801	G	C	MI.7898	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	595	199	V	L	Gta/Cta	-3,8	0	0	benign	0	neutral	0,61	neutral	2,41	neutral	0,51	neutral	-1,16	neutral_impact	0,74	damaging	0,58	neutral	0,69	neutral	1,63	14,04	0,16	0,45	neutral	0,14	disease	0,59	neutral	0,32	neutral	0,43	1	neutral	0,38	deleterious	0,81	neutral	-6	neutral	0,16	high_impact	2,05	medium_impact	0,3	medium_impact	-0,52	0,4	0,8	16,48	24,65	N	0,34	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9801	9801	G	T	MI.7899	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	595	199	V	L	Gta/Tta	-3,8	0	0	benign	0	neutral	0,61	neutral	2,41	neutral	0,51	neutral	-1,16	neutral_impact	0,74	damaging	0,58	neutral	0,69	neutral	1,8	14,96	0,16	0,45	neutral	0,14	disease	0,59	neutral	0,32	neutral	0,43	1	neutral	0,38	deleterious	0,81	neutral	-6	neutral	0,16	high_impact	2,05	medium_impact	0,3	medium_impact	-0,52	0,4	0,8	16,48	24,65	N	0,34	N	0,36	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8561	8561	C	G	MI.79	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	35	12	P	R	cCc/cGc	7,3	1	0	probably_damaging	1	deleterious	0,02	neutral	4,64	neutral	0,07	deleterious	-7,81	medium_impact	3,02	neutral	0,62	damaging	0,06	deleterious	3,37	22,9	0,31	0,65	disease	0,54	disease	0,92	disease	0,78	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,83	low_impact	-3,6	medium_impact	-0,66	medium_impact	1,49	0,58	0,9	50	8,94	N	0,46	N	0,72	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	C8561G	Ataxia neuropathy,DM,SNHL,and hypogonadism	+	+	Reported	1
chrM	8897	8897	C	A	MI.790	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	371	124	A	D	gCc/gAc	1,52	0,6	0	benign	0,16	neutral	0,15	neutral	3,83	deleterious	-3,06	neutral	-2,21	medium_impact	3,21	neutral	0,75	neutral	0,47	deleterious	2,69	20,7	0,3	0,65	disease	0,64	disease	0,89	disease	0,71	disease	0,75	5	neutral	0,83	deleterious	0,5	neutral	-3	deleterious	0,44	medium_impact	-0,07	medium_impact	-0,13	medium_impact	1,65	0,54	0,9	19,91	7,92	N	0,31	N	0,23	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9801	9801	G	A	MI.7900	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	595	199	V	M	Gta/Ata	-3,8	0	0	benign	0,02	neutral	0,26	neutral	2,24	neutral	-0,22	neutral	-0,33	neutral_impact	0,5	neutral	0,69	neutral	0,77	deleterious	0,31	5,8	0,18	0,45	neutral	0,29	neutral	0,12	neutral	0,28	neutral	0,25	5	neutral	0,73	deleterious	0,62	neutral	-6	neutral	0,13	medium_impact	0,77	medium_impact	-0,07	medium_impact	-0,73	0,65	0,8	16,48	24,65	N	0,54	P	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9802	9802	T	G	MI.7901	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	596	199	V	G	gTa/gGa	0,36	0,09	0	possibly_damaging	0,49	neutral	0,51	neutral	2,12	deleterious	-3,06	deleterious	-5,56	medium_impact	2,56	damaging	0,59	neutral	0,56	deleterious	3,82	23,4	0,03	0,35	neutral	0,49	disease	0,8	disease	0,6	disease	0,71	4	neutral	0,48	deleterious	0,51	NA	0	deleterious	0,59	medium_impact	-0,85	medium_impact	0,2	medium_impact	1,11	0,25	0,8	16,48	24,65	N	0,33	N	0,73	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9802	9802	T	A	MI.7902	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	596	199	V	E	gTa/gAa	0,36	0,09	0	benign	0,3	neutral	0,25	neutral	2,13	deleterious	-3,61	deleterious	-4,61	high_impact	3,81	damaging	0,55	neutral	0,42	deleterious	4,45	24,2	0,02	0,35	disease	0,5	disease	0,89	disease	0,72	disease	0,79	6	neutral	0,7	deleterious	0,48	neutral	-2	deleterious	0,48	medium_impact	-0,51	medium_impact	-0,08	high_impact	2,23	0,22	0,8	16,48	24,65	N	0,47	N	0,87	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9802	9802	T	C	MI.7903	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	596	199	V	A	gTa/gCa	0,36	0,09	0	benign	0,15	neutral	0,6	neutral	2,23	neutral	-1,02	deleterious	-3,04	medium_impact	1,97	damaging	0,6	neutral	0,58	deleterious	2,04	16,49	0,08	0,35	neutral	0,18	disease	0,59	neutral	0,49	neutral	0,45	1	neutral	0,29	deleterious	0,73	neutral	-3	neutral	0,21	medium_impact	-0,14	medium_impact	0,29	medium_impact	0,58	0,16	0,8	16,48	24,65	N	0,36	N	0,55	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9804	9804	G	C	MI.7904	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	598	200	A	P	Gcc/Ccc	-4,5	0	0,01	probably_damaging	0,93	neutral	0,2	neutral	2,44	deleterious	-3,29	deleterious	-4,49	high_impact	4,29	damaging	0,58	neutral	0,36	deleterious	3,89	23,5	0,02	0,35	disease	0,51	disease	0,91	disease	0,75	disease	0,8	6	neutral	0,96	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-1,96	medium_impact	-0,15	high_impact	2,66	0,59	0,8	73,95	10,14	N	0,49	N	0,94	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9804	9804	G	A	MI.7905	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	598	200	A	T	Gcc/Acc	-4,5	0	0,01	benign	0,01	neutral	0,47	neutral	2,54	neutral	-0,32	deleterious	-3,26	medium_impact	2,1	damaging	0,19	neutral	0,31	deleterious	2,33	18,38	0,16	0,45	neutral	0,2	disease	0,78	neutral	0,43	disease	0,5	0	neutral	0,52	deleterious	0,73	neutral	-3	neutral	0,25	medium_impact	1,07	medium_impact	0,16	medium_impact	0,7	0,71	0,85	73,95	10,14	P	0,86	P	0,85	disease_causing_automatic	0	0,08	rs200613617	Pathogenic	Leber's_optic_atrophy	RCV000010287.2	MedGen:OMIM:SNOMED_CT	pancreatic cancer cell line	.	CPD	3,26	G9804A	LHON	+	-	Reported	8
chrM	9804	9804	G	T	MI.7906	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	598	200	A	S	Gcc/Tcc	-4,5	0	0,01	benign	0,24	neutral	0,41	neutral	2,47	neutral	-1,64	deleterious	-2,53	medium_impact	2,5	damaging	0,46	neutral	0,58	deleterious	2,19	17,41	0,2	0,45	neutral	0,23	disease	0,79	neutral	0,44	disease	0,5	0	neutral	0,5	deleterious	0,59	neutral	-3	neutral	0,3	medium_impact	-0,38	medium_impact	0,1	medium_impact	1,06	0,44	0,8	73,95	10,14	N	0,45	N	0,49	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9805	9805	C	A	MI.7907	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	599	200	A	D	gCc/gAc	4,29	1	0	probably_damaging	0,91	neutral	0,22	neutral	2,43	deleterious	-4	deleterious	-5,35	high_impact	4,29	neutral	0,65	neutral	0,36	deleterious	4,69	24,6	0,01	0,35	neutral	0,48	disease	0,94	disease	0,73	disease	0,85	7	neutral	0,94	neutral	0,16	deleterious	2	deleterious	0,8	low_impact	-1,85	medium_impact	-0,12	high_impact	2,66	0,39	0,8	73,95	10,14	P	0,55	P	0,99	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9805	9805	C	G	MI.7908	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	599	200	A	G	gCc/gGc	4,29	1	0	benign	0,1	neutral	0,42	neutral	2,45	neutral	-2,4	deleterious	-3,64	medium_impact	2,82	damaging	0,53	neutral	0,54	deleterious	2,29	18,11	0,13	0,4	neutral	0,35	disease	0,8	disease	0,61	disease	0,54	1	neutral	0,52	deleterious	0,66	neutral	-3	neutral	0,28	medium_impact	0,06	medium_impact	0,11	medium_impact	1,35	0,66	0,8	73,95	10,14	N	0,48	N	0,66	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9805	9805	C	T	MI.7909	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	599	200	A	V	gCc/gTc	4,29	1	0	benign	0,16	neutral	0,58	neutral	2,51	neutral	-0,48	deleterious	-3,58	high_impact	3,73	damaging	0,55	neutral	0,43	deleterious	2,84	21,6	0,1	0,4	neutral	0,17	disease	0,9	disease	0,64	disease	0,72	4	neutral	0,31	deleterious	0,71	neutral	-2	deleterious	0,51	medium_impact	-0,17	medium_impact	0,27	high_impact	2,16	0,68	0,85	73,95	10,14	P	0,53	P	0,49	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8897	8897	C	G	MI.791	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	371	124	A	G	gCc/gGc	1,52	0,6	0	benign	0,11	neutral	0,24	neutral	3,85	neutral	-0,34	neutral	-1,77	medium_impact	2,51	neutral	0,76	neutral	0,58	deleterious	2,17	17,32	0,39	0,65	neutral	0,43	disease	0,69	disease	0,57	disease	0,68	4	neutral	0,73	deleterious	0,57	neutral	-3	neutral	0,25	medium_impact	0,11	medium_impact	0,01	medium_impact	1,05	0,74	0,9	19,91	7,92	N	0,34	N	0,27	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9807	9807	A	T	MI.7910	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	601	201	T	S	Aca/Tca	-13,06	0	0	probably_damaging	0,95	neutral	0,4	neutral	1,92	deleterious	-3,66	deleterious	-3,71	high_impact	4,43	neutral	0,68	damaging	0,03	deleterious	3,5	23,1	0,17	0,45	neutral	0,43	disease	0,8	disease	0,76	disease	0,74	5	neutral	0,95	neutral	0,23	deleterious	2	deleterious	0,77	low_impact	-2,11	medium_impact	0,09	high_impact	2,79	0,76	0,85	73,95	11,6	N	0,46	N	0,77	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9807	9807	A	C	MI.7911	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	601	201	T	P	Aca/Cca	-13,06	0	0	probably_damaging	0,99	neutral	0,2	neutral	1,88	deleterious	-5,92	deleterious	-5,62	high_impact	4,79	neutral	0,64	damaging	0,05	deleterious	3,59	23,2	0,03	0,35	disease	0,69	disease	0,86	disease	0,86	disease	0,81	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-2,81	medium_impact	-0,15	high_impact	3,11	0,48	0,8	73,95	11,6	P	0,6	P	0,98	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9807	9807	A	G	MI.7912	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	601	201	T	A	Aca/Gca	-13,06	0	0	probably_damaging	0,95	neutral	0,52	neutral	1,93	deleterious	-3,47	deleterious	-4,63	high_impact	4,43	neutral	0,65	damaging	0,04	deleterious	3,56	23,1	0,07	0,35	neutral	0,29	disease	0,75	disease	0,76	disease	0,73	5	neutral	0,95	neutral	0,29	deleterious	2	deleterious	0,72	low_impact	-2,11	medium_impact	0,21	high_impact	2,79	0,5	0,8	73,95	11,6	N	0,44	N	0,44	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9808	9808	C	A	MI.7913	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	602	201	T	K	aCa/aAa	5,68	1	0	probably_damaging	0,99	neutral	0,29	neutral	1,89	deleterious	-4,76	deleterious	-5,59	high_impact	4,79	neutral	0,68	damaging	0,02	deleterious	4,57	24,4	0,05	0,35	disease	0,54	disease	0,91	disease	0,85	disease	0,83	7	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-2,81	medium_impact	-0,03	high_impact	3,11	0,41	0,8	73,95	11,6	P	0,75	P	0,99	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9808	9808	C	T	MI.7914	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	602	201	T	M	aCa/aTa	5,68	1	0	probably_damaging	1	neutral	0,23	neutral	1,88	deleterious	-5,03	deleterious	-5,62	high_impact	4,43	neutral	0,68	damaging	0,01	deleterious	4,15	23,8	0,05	0,35	disease	0,59	disease	0,85	disease	0,8	disease	0,78	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,11	high_impact	2,79	0,58	0,8	73,95	11,6	P	0,57	P	0,96	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9810	9810	G	C	MI.7915	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	604	202	G	R	Ggc/Cgc	-4,96	0	0	probably_damaging	1	neutral	0,35	neutral	0,9	deleterious	-6,58	deleterious	-7,57	high_impact	4,79	neutral	0,63	damaging	0,02	deleterious	4,06	23,7	0,02	0,35	disease	0,77	disease	0,94	disease	0,84	disease	0,88	8	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,78	medium_impact	0,04	high_impact	3,11	0,67	0,85	72,8	11,69	P	0,58	P	0,99	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9810	9810	G	T	MI.7916	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	604	202	G	C	Ggc/Tgc	-4,96	0	0	probably_damaging	1	neutral	0,18	neutral	0,89	deleterious	-7,58	deleterious	-8,51	high_impact	4,44	damaging	0,56	damaging	0,02	deleterious	4,24	23,9	0,03	0,35	disease	0,87	disease	0,94	disease	0,77	disease	0,87	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,78	medium_impact	-0,18	high_impact	2,8	0,24	0,8	72,8	11,69	N	0,44	N	0,98	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9810	9810	G	A	MI.7917	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	604	202	G	S	Ggc/Agc	-4,96	0	0	probably_damaging	1	neutral	0,44	neutral	0,94	deleterious	-5,26	deleterious	-5,64	high_impact	4,09	damaging	0,56	damaging	0,02	deleterious	4,27	23,9	0,04	0,35	disease	0,56	disease	0,88	disease	0,73	disease	0,77	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	0,13	high_impact	2,48	0,65	0,8	72,8	11,69	N	0,28	N	0,85	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9811	9811	G	A	MI.7918	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	605	202	G	D	gGc/gAc	7,3	1	0	probably_damaging	1	neutral	0,25	neutral	0,91	deleterious	-6,07	deleterious	-6,62	high_impact	4,79	damaging	0,49	damaging	0,02	deleterious	3,96	23,6	0,02	0,35	disease	0,62	disease	0,92	disease	0,83	disease	0,85	7	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,88	low_impact	-3,78	medium_impact	-0,08	high_impact	3,11	0,11	0,8	72,8	11,69	P	0,66	P	0,98	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9811	9811	G	T	MI.7919	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	605	202	G	V	gGc/gTc	7,3	1	0	probably_damaging	1	neutral	0,68	neutral	0,9	deleterious	-6,37	deleterious	-8,52	high_impact	4,79	damaging	0,52	damaging	0,01	deleterious	3,86	23,5	0,02	0,35	disease	0,76	disease	0,94	disease	0,79	disease	0,88	8	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,89	low_impact	-3,78	medium_impact	0,38	high_impact	3,11	0,2	0,8	72,8	11,69	P	0,59	P	0,97	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8897	8897	C	T	MI.792	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	371	124	A	V	gCc/gTc	1,52	0,6	0	benign	0,11	neutral	0,4	neutral	3,92	neutral	0	deleterious	-2,74	low_impact	1,88	neutral	0,79	neutral	0,66	deleterious	2,63	20,4	0,3	0,65	neutral	0,4	disease	0,72	neutral	0,46	neutral	0,24	5	neutral	0,54	deleterious	0,65	neutral	-6	neutral	0,25	medium_impact	0,11	medium_impact	0,19	medium_impact	0,51	0,72	0,9	19,91	7,92	N	0,28	N	0,31	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9811	9811	G	C	MI.7920	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	605	202	G	A	gGc/gCc	7,3	1	0	probably_damaging	1	neutral	0,62	neutral	0,95	deleterious	-4,99	deleterious	-5,66	high_impact	4,09	damaging	0,57	damaging	0,01	deleterious	3,21	22,7	0,05	0,35	disease	0,53	disease	0,81	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	0,31	high_impact	2,48	0,47	0,8	72,8	11,69	N	0,48	N	0,3	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9813	9813	T	C	MI.7921	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	607	203	F	L	Ttc/Ctc	-5,19	0	0	probably_damaging	0,95	neutral	0,66	neutral	2,26	neutral	-0,22	deleterious	-5,63	medium_impact	2,58	damaging	0,58	neutral	0,54	deleterious	4,21	23,9	0,25	0,45	neutral	0,13	disease	0,72	neutral	0,49	neutral	0,48	0	neutral	0,94	neutral	0,36	deleterious	1	deleterious	0,71	low_impact	-2,11	medium_impact	0,36	medium_impact	1,13	0,59	0,8	74,33	11,75	N	0,26	N	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9813	9813	T	A	MI.7922	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	607	203	F	I	Ttc/Atc	-5,19	0	0	probably_damaging	0,97	neutral	0,4	neutral	1,98	neutral	-2,1	deleterious	-5,64	high_impact	3,83	neutral	0,64	neutral	0,58	deleterious	4,56	24,4	0,14	0,4	neutral	0,2	disease	0,86	disease	0,68	disease	0,72	4	neutral	0,97	neutral	0,22	deleterious	2	deleterious	0,76	low_impact	-2,34	medium_impact	0,09	high_impact	2,25	0,3	0,8	74,33	11,75	N	0,39	N	0,96	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9813	9813	T	G	MI.7923	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	607	203	F	V	Ttc/Gtc	-5,19	0	0	probably_damaging	0,98	neutral	0,49	neutral	1,97	neutral	-2,24	deleterious	-6,59	high_impact	4,72	damaging	0,58	neutral	0,49	deleterious	4,26	23,9	0,09	0,35	neutral	0,21	disease	0,9	disease	0,68	disease	0,73	5	deleterious	0,98	neutral	0,26	deleterious	2	deleterious	0,76	low_impact	-2,51	medium_impact	0,18	high_impact	3,05	0,19	0,8	74,33	11,75	P	0,56	P	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9814	9814	T	A	MI.7924	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	608	203	F	Y	tTc/tAc	7,53	1	0	probably_damaging	0,95	neutral	1	neutral	1,94	neutral	-2,61	deleterious	-2,84	high_impact	4,72	neutral	0,66	neutral	0,37	deleterious	4,39	24,1	0,16	0,45	neutral	0,44	disease	0,84	disease	0,7	disease	0,73	5	neutral	0,95	deleterious	0,53	deleterious	2	deleterious	0,78	low_impact	-2,11	high_impact	1,9	high_impact	3,05	0,49	0,8	74,33	11,75	P	0,7	P	0,8	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9814	9814	T	G	MI.7925	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	608	203	F	C	tTc/tGc	7,53	1	0	probably_damaging	1	neutral	0,17	neutral	1,87	deleterious	-5,41	deleterious	-7,55	high_impact	4,72	neutral	0,63	neutral	0,41	deleterious	4,24	23,9	0,04	0,35	disease	0,57	disease	0,89	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	-0,2	high_impact	3,05	0,12	0,8	74,33	11,75	P	0,62	P	0,98	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9814	9814	T	C	MI.7926	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	608	203	F	S	tTc/tCc	7,53	1	0	probably_damaging	0,99	neutral	0,4	neutral	1,89	deleterious	-4,07	deleterious	-7,56	high_impact	4,37	neutral	0,72	neutral	0,55	deleterious	4,38	24,1	0,03	0,35	neutral	0,34	disease	0,86	disease	0,67	disease	0,72	4	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-2,81	medium_impact	0,09	high_impact	2,73	0,14	0,8	74,33	11,75	P	0,56	P	0,96	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9815	9815	C	A	MI.7927	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	609	203	F	L	ttC/ttA	5,68	1	0	probably_damaging	0,95	neutral	0,66	neutral	2,26	neutral	-0,22	deleterious	-5,63	medium_impact	2,58	damaging	0,58	neutral	0,54	deleterious	4,76	24,7	0,25	0,45	neutral	0,13	disease	0,72	neutral	0,49	neutral	0,48	0	neutral	0,94	neutral	0,36	deleterious	1	deleterious	0,71	low_impact	-2,11	medium_impact	0,36	medium_impact	1,13	0,59	0,8	74,33	11,75	N	0,43	N	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9815	9815	C	G	MI.7928	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	609	203	F	L	ttC/ttG	5,68	1	0	probably_damaging	0,95	neutral	0,66	neutral	2,26	neutral	-0,22	deleterious	-5,63	medium_impact	2,58	damaging	0,58	neutral	0,54	deleterious	4,48	24,2	0,25	0,45	neutral	0,13	disease	0,72	neutral	0,49	neutral	0,48	0	neutral	0,94	neutral	0,36	deleterious	1	deleterious	0,71	low_impact	-2,11	medium_impact	0,36	medium_impact	1,13	0,59	0,8	74,33	11,75	N	0,42	N	0,92	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9816	9816	C	A	MI.7929	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	610	204	H	N	Cac/Aac	-3,11	0	0	probably_damaging	0,99	neutral	0,31	deleterious	-1,84	deleterious	-11,11	deleterious	-6,58	high_impact	4,79	neutral	0,62	damaging	0,02	deleterious	3,99	23,6	0,08	0,35	disease	0,85	disease	0,83	disease	0,82	disease	0,84	7	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-2,81	medium_impact	-0,01	high_impact	3,11	0,2	0,8	73,95	11,69	N	0,53	P	0,96	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8899	8899	C	A	MI.793	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	373	125	L	M	Cta/Ata	-7,74	0	0	possibly_damaging	0,86	neutral	0,08	neutral	4,09	deleterious	-4,66	neutral	-1,78	medium_impact	2,68	neutral	0,76	neutral	0,61	deleterious	3,68	23,3	0,31	0,65	disease	0,74	disease	0,55	disease	0,55	disease	0,51	0	neutral	0,96	neutral	0,11	NA	0	deleterious	0,7	low_impact	-1,5	medium_impact	-0,31	medium_impact	1,2	0,63	0,9	48,23	8,39	N	0,34	N	0,96	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9816	9816	C	G	MI.7930	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	610	204	H	D	Cac/Gac	-3,11	0	0	probably_damaging	1	neutral	0,2	deleterious	-1,85	deleterious	-13,06	deleterious	-8,47	high_impact	4,79	neutral	0,64	damaging	0,01	deleterious	3,98	23,6	0,04	0,35	disease	0,82	disease	0,85	disease	0,87	disease	0,83	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	-0,15	high_impact	3,11	0,2	0,8	73,95	11,69	N	0,44	N	0,98	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9816	9816	C	T	MI.7931	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	610	204	H	Y	Cac/Tac	-3,11	0	0	probably_damaging	0,99	neutral	1	deleterious	-1,84	deleterious	-10,91	deleterious	-5,65	high_impact	4,45	neutral	0,64	damaging	0,02	deleterious	3,81	23,4	0,04	0,35	disease	0,8	disease	0,89	disease	0,81	disease	0,84	7	deleterious	0,99	deleterious	0,51	deleterious	2	deleterious	0,88	low_impact	-2,81	high_impact	1,9	high_impact	2,81	0,21	0,8	73,95	11,69	N	0,41	N	0,99	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9817	9817	A	T	MI.7932	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	611	204	H	L	cAc/cTc	7,3	1	0	probably_damaging	1	neutral	0,66	deleterious	-1,86	deleterious	-14,23	deleterious	-10,36	high_impact	4,79	damaging	0,6	damaging	0,02	deleterious	3,95	23,6	0,03	0,35	disease	0,84	disease	0,9	disease	0,81	disease	0,84	7	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	0,36	high_impact	3,11	0,17	0,8	73,95	11,69	P	0,56	P	0,96	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9817	9817	A	C	MI.7933	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	611	204	H	P	cAc/cCc	7,3	1	0	probably_damaging	1	neutral	0,2	deleterious	-1,85	deleterious	-13,42	deleterious	-9,42	high_impact	4,79	neutral	0,61	damaging	0,02	deleterious	3,33	22,9	0,03	0,35	disease	0,89	disease	0,87	disease	0,88	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-3,78	medium_impact	-0,15	high_impact	3,11	0,14	0,8	73,95	11,69	P	0,53	P	0,98	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9817	9817	A	G	MI.7934	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	611	204	H	R	cAc/cGc	7,3	1	0	probably_damaging	1	neutral	0,35	deleterious	-1,85	deleterious	-12,68	deleterious	-7,5	high_impact	4,79	neutral	0,72	damaging	0,02	deleterious	3,1	22,5	0,04	0,35	disease	0,81	disease	0,88	disease	0,85	disease	0,85	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,78	medium_impact	0,04	high_impact	3,11	0,33	0,8	73,95	11,69	P	0,58	P	0,99	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9818	9818	C	A	MI.7935	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	612	204	H	Q	caC/caA	8,69	1	0	probably_damaging	1	neutral	0,29	deleterious	-1,85	deleterious	-11,93	deleterious	-7,49	high_impact	4,24	neutral	0,65	damaging	0,02	deleterious	4,03	23,6	0,05	0,35	disease	0,86	disease	0,83	disease	0,82	disease	0,84	7	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,03	high_impact	2,62	0,3	0,8	73,95	11,69	P	0,54	P	0,94	polymorphism	1	0,34	rs2854139	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9818	9818	C	G	MI.7936	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	612	204	H	Q	caC/caG	8,69	1	0	probably_damaging	1	neutral	0,29	deleterious	-1,85	deleterious	-11,93	deleterious	-7,49	high_impact	4,24	neutral	0,65	damaging	0,02	deleterious	3,65	23,2	0,05	0,35	disease	0,86	disease	0,83	disease	0,82	disease	0,84	7	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,03	high_impact	2,62	0,3	0,8	73,95	11,69	P	0,53	P	0,94	polymorphism	1	0,34	rs2854139	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9819	9819	G	C	MI.7937	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	613	205	G	R	Gga/Cga	-6,35	0	0	probably_damaging	1	neutral	0,12	neutral	1,9	deleterious	-4,94	deleterious	-7,51	high_impact	4,77	neutral	0,66	damaging	0,03	deleterious	4,06	23,7	0,02	0,35	disease	0,58	disease	0,91	disease	0,78	disease	0,81	6	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,88	low_impact	-3,78	medium_impact	-0,3	high_impact	3,09	0,36	0,8	74,33	11,77	P	0,58	P	0,99	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9819	9819	G	T	MI.7938	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	613	205	G	W	Gga/Tga	-6,35	0	0	probably_damaging	1	neutral	0,07	neutral	1,88	deleterious	-6,56	deleterious	-7,56	high_impact	4,77	neutral	0,64	damaging	0,02	deleterious	4,52	24,3	0,04	0,35	disease	0,87	disease	0,9	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,89	low_impact	-3,78	medium_impact	-0,45	high_impact	3,09	0,12	0,8	74,33	11,77	N	0,53	P	0,98	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9820	9820	G	A	MI.7939	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	614	205	G	E	gGa/gAa	6,14	1	0	probably_damaging	1	neutral	0,09	neutral	1,9	deleterious	-4,9	deleterious	-7,54	high_impact	4,77	damaging	0,58	damaging	0,01	deleterious	3,93	23,5	0,02	0,35	disease	0,5	disease	0,88	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,38	high_impact	3,09	0,25	0,8	74,33	11,77	P	0,66	P	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8899	8899	C	G	MI.794	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	373	125	L	V	Cta/Gta	-7,74	0	0	benign	0,28	deleterious	0,03	neutral	4,1	deleterious	-3,67	deleterious	-2,69	medium_impact	2,42	neutral	0,71	neutral	0,52	neutral	1,68	14,28	0,26	0,65	neutral	0,38	disease	0,59	disease	0,55	neutral	0,43	2	neutral	0,97	neutral	0,38	deleterious	1	neutral	0,38	medium_impact	-0,37	medium_impact	-0,56	medium_impact	0,98	0,61	0,9	48,23	8,39	N	0,39	N	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9820	9820	G	C	MI.7940	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	614	205	G	A	gGa/gCa	6,14	1	0	probably_damaging	0,99	neutral	0,2	neutral	2,02	neutral	-2,52	deleterious	-5,66	medium_impact	3,27	damaging	0,59	damaging	0	deleterious	3,2	22,7	0,09	0,35	neutral	0,35	disease	0,71	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,79	low_impact	-2,81	medium_impact	-0,15	medium_impact	1,75	0,48	0,8	74,33	11,77	N	0,43	N	0,3	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9820	9820	G	T	MI.7941	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	614	205	G	V	gGa/gTa	6,14	1	0	probably_damaging	1	neutral	0,29	neutral	1,92	deleterious	-4,05	deleterious	-8,51	high_impact	4,42	damaging	0,54	damaging	0,02	deleterious	3,83	23,4	0,03	0,35	neutral	0,46	disease	0,9	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,03	high_impact	2,78	0,22	0,8	74,33	11,77	N	0,51	P	0,97	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9822	9822	C	A	MI.7942	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	616	206	L	I	Ctt/Att	-13,98	0	0	benign	0,12	neutral	0,36	neutral	2,02	neutral	-1,22	neutral	-1,43	medium_impact	2,26	damaging	0,58	neutral	0,71	deleterious	3,78	23,4	0,3	0,45	neutral	0,17	disease	0,51	neutral	0,32	neutral	0,44	1	neutral	0,58	deleterious	0,62	neutral	-3	neutral	0,17	medium_impact	-0,03	medium_impact	0,05	medium_impact	0,84	0,56	0,8	76,25	10,72	N	0,48	N	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9822	9822	C	G	MI.7943	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	616	206	L	V	Ctt/Gtt	-13,98	0	0	benign	0,05	neutral	0,27	neutral	1,94	neutral	-1,83	neutral	-2,29	medium_impact	3,05	damaging	0,53	neutral	0,49	neutral	1,78	14,86	0,25	0,45	neutral	0,19	disease	0,68	disease	0,58	disease	0,6	2	neutral	0,71	deleterious	0,61	neutral	-3	neutral	0,17	medium_impact	0,37	medium_impact	-0,06	medium_impact	1,55	0,61	0,8	76,25	10,72	N	0,44	N	0,81	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9822	9822	C	T	MI.7944	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	616	206	L	F	Ctt/Ttt	-13,98	0	0	benign	0,01	neutral	0,29	neutral	1,87	neutral	-2,55	deleterious	-3,3	low_impact	1,24	damaging	0,53	neutral	0,7	deleterious	2,15	17,2	0,22	0,45	neutral	0,22	neutral	0,46	neutral	0,33	neutral	0,42	2	neutral	0,71	deleterious	0,64	neutral	-6	neutral	0,16	medium_impact	1,07	medium_impact	-0,03	medium_impact	-0,07	0,61	0,8	76,25	10,72	N	0,52	P	0,95	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9823	9823	T	A	MI.7945	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	617	206	L	H	cTt/cAt	0,59	0,17	0	possibly_damaging	0,83	neutral	0,15	neutral	1,76	deleterious	-5,84	deleterious	-6,09	high_impact	4,33	damaging	0,57	neutral	0,4	deleterious	4,36	24,1	0,03	0,35	disease	0,54	disease	0,85	disease	0,67	disease	0,72	4	neutral	0,92	neutral	0,16	deleterious	1	deleterious	0,74	low_impact	-1,54	medium_impact	-0,24	high_impact	2,7	0,31	0,8	76,25	10,72	N	0,42	N	0,97	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9823	9823	T	C	MI.7946	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	617	206	L	P	cTt/cCt	0,59	0,17	0	possibly_damaging	0,88	neutral	0,06	neutral	1,77	deleterious	-5,69	deleterious	-6,12	high_impact	4,33	damaging	0,54	neutral	0,4	deleterious	4,07	23,7	0,01	0,35	disease	0,55	disease	0,88	disease	0,71	disease	0,78	6	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,8	low_impact	-1,71	medium_impact	-0,49	high_impact	2,7	0,38	0,8	76,25	10,72	N	0,45	N	0,99	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9823	9823	T	G	MI.7947	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	617	206	L	R	cTt/cGt	0,59	0,17	0	possibly_damaging	0,69	neutral	0,08	neutral	1,77	deleterious	-5,13	deleterious	-5,3	high_impact	4,33	damaging	0,57	neutral	0,32	deleterious	4,34	24,1	0,01	0,35	neutral	0,45	disease	0,92	disease	0,7	disease	0,79	6	neutral	0,93	neutral	0,2	deleterious	1	deleterious	0,7	low_impact	-1,21	medium_impact	-0,41	high_impact	2,7	0,22	0,8	76,25	10,72	N	0,4	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9825	9825	C	A	MI.7948	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	619	207	H	N	Cac/Aac	-11,9	0	0	probably_damaging	0,99	neutral	0,31	deleterious	-1,6	deleterious	-10,79	deleterious	-6,64	high_impact	4,79	damaging	0,59	damaging	0,02	deleterious	4,01	23,6	0,06	0,35	disease	0,83	disease	0,85	disease	0,76	disease	0,8	6	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-2,81	medium_impact	-0,01	high_impact	3,11	0,19	0,8	73,56	11,76	N	0,48	N	0,96	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9825	9825	C	G	MI.7949	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	619	207	H	D	Cac/Gac	-11,9	0	0	probably_damaging	1	neutral	0,2	deleterious	-1,6	deleterious	-10,88	deleterious	-8,53	high_impact	4,79	damaging	0,59	damaging	0,02	deleterious	3,97	23,6	0,04	0,35	disease	0,79	disease	0,87	disease	0,82	disease	0,83	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	-0,15	high_impact	3,11	0,17	0,8	73,56	11,76	N	0,44	N	0,98	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8900	8900	T	C	MI.795	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	374	125	L	P	cTa/cCa	-0,57	0	0	probably_damaging	0,9	deleterious	0	neutral	4,08	deleterious	-5,82	deleterious	-6,37	high_impact	3,81	damaging	0,44	neutral	0,44	deleterious	3,85	23,4	0,12	0,65	disease	0,57	disease	0,87	disease	0,8	disease	0,77	5	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,82	low_impact	-1,66	low_impact	-1,4	high_impact	2,17	0,58	0,9	48,23	8,39	P	0,54	P	1	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9825	9825	C	T	MI.7950	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	619	207	H	Y	Cac/Tac	-11,9	0	0	probably_damaging	0,99	neutral	1	deleterious	-1,6	deleterious	-10,91	deleterious	-5,69	high_impact	4,44	neutral	0,61	damaging	0,02	deleterious	3,82	23,4	0,03	0,35	disease	0,77	disease	0,9	disease	0,75	disease	0,8	6	deleterious	0,99	deleterious	0,51	deleterious	2	deleterious	0,87	low_impact	-2,81	high_impact	1,9	high_impact	2,8	0,25	0,8	73,56	11,76	N	0,34	N	0,99	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9826	9826	A	G	MI.7951	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	620	207	H	R	cAc/cGc	5,45	1	0	probably_damaging	0,99	neutral	0,35	deleterious	-1,61	deleterious	-12,31	deleterious	-7,58	high_impact	4,79	neutral	0,67	damaging	0,03	deleterious	3,07	22,4	0,02	0,35	disease	0,78	disease	0,9	disease	0,8	disease	0,8	6	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-2,81	medium_impact	0,04	high_impact	3,11	0,28	0,8	73,56	11,76	P	0,53	P	0,99	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9826	9826	A	T	MI.7952	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	620	207	H	L	cAc/cTc	5,45	1	0	probably_damaging	0,99	neutral	0,71	deleterious	-1,61	deleterious	-13,76	deleterious	-10,44	high_impact	4,79	damaging	0,57	damaging	0,02	deleterious	3,88	23,5	0,02	0,35	disease	0,82	disease	0,91	disease	0,76	disease	0,82	6	deleterious	0,99	neutral	0,36	deleterious	2	deleterious	0,87	low_impact	-2,81	medium_impact	0,41	high_impact	3,11	0,17	0,8	73,56	11,76	P	0,53	P	0,96	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9826	9826	A	C	MI.7953	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	620	207	H	P	cAc/cCc	5,45	1	0	probably_damaging	1	neutral	0,2	deleterious	-1,61	deleterious	-13,09	deleterious	-9,48	high_impact	4,44	damaging	0,58	damaging	0,03	deleterious	3,36	22,9	0,02	0,35	disease	0,88	disease	0,89	disease	0,84	disease	0,86	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-3,78	medium_impact	-0,15	high_impact	2,8	0,14	0,8	73,56	11,76	P	0,5	N	0,98	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9827	9827	C	A	MI.7954	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	621	207	H	Q	caC/caA	5,68	1	0	probably_damaging	1	neutral	0,29	deleterious	-1,6	deleterious	-11,6	deleterious	-7,57	high_impact	4,79	neutral	0,61	damaging	0,02	deleterious	4,08	23,7	0,03	0,35	disease	0,83	disease	0,85	disease	0,76	disease	0,8	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,03	high_impact	3,11	0,26	0,8	73,56	11,76	P	0,55	P	0,94	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9827	9827	C	G	MI.7955	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	621	207	H	Q	caC/caG	5,68	1	0	probably_damaging	1	neutral	0,29	deleterious	-1,6	deleterious	-11,6	deleterious	-7,57	high_impact	4,79	neutral	0,61	damaging	0,02	deleterious	3,71	23,3	0,03	0,35	disease	0,83	disease	0,85	disease	0,76	disease	0,8	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,03	high_impact	3,11	0,26	0,8	73,56	11,76	P	0,55	P	0,94	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9828	9828	G	T	MI.7956	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	622	208	V	F	Gtc/Ttc	-5,89	0	0	probably_damaging	1	neutral	0,45	neutral	1,16	deleterious	-7,17	deleterious	-4,75	high_impact	4,78	damaging	0,53	neutral	0,52	deleterious	3,92	23,5	0,02	0,35	disease	0,68	disease	0,93	disease	0,71	disease	0,81	6	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	0,14	high_impact	3,1	0,33	0,8	73,95	11,68	P	0,61	P	0,94	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9828	9828	G	A	MI.7957	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	622	208	V	I	Gtc/Atc	-5,89	0	0	probably_damaging	0,92	neutral	0,56	neutral	1,3	deleterious	-3,89	neutral	-0,95	high_impact	3,81	damaging	0,56	neutral	0,65	deleterious	3,77	23,4	0,22	0,45	neutral	0,24	disease	0,68	disease	0,6	disease	0,59	2	neutral	0,91	neutral	0,32	deleterious	2	deleterious	0,68	low_impact	-1,9	medium_impact	0,25	high_impact	2,23	0,8	0,85	73,95	11,68	N	0,37	N	0,21	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9828	9828	G	C	MI.7958	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	622	208	V	L	Gtc/Ctc	-5,89	0	0	probably_damaging	0,92	neutral	1	neutral	1,28	deleterious	-4,17	deleterious	-2,85	high_impact	4,43	damaging	0,56	neutral	0,58	deleterious	3,68	23,3	0,06	0,35	neutral	0,34	disease	0,81	disease	0,65	disease	0,68	4	neutral	0,92	deleterious	0,54	deleterious	2	deleterious	0,74	low_impact	-1,9	high_impact	1,9	high_impact	2,79	0,34	0,8	73,95	11,68	N	0,38	N	0,68	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9829	9829	T	C	MI.7959	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	623	208	V	A	gTc/gCc	4,29	1	0	probably_damaging	0,99	neutral	0,23	neutral	1,23	deleterious	-4,78	deleterious	-3,8	high_impact	4,22	damaging	0,56	neutral	0,67	deleterious	3,68	23,3	0,03	0,35	disease	0,59	disease	0,7	disease	0,63	disease	0,66	3	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,8	low_impact	-2,81	medium_impact	-0,11	high_impact	2,6	0,18	0,8	73,95	11,68	P	0,54	P	0,39	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8900	8900	T	G	MI.796	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	374	125	L	R	cTa/cGa	-0,57	0	0	possibly_damaging	0,86	deleterious	0	neutral	4,08	deleterious	-5,22	deleterious	-5,43	high_impact	4,15	damaging	0,52	neutral	0,39	deleterious	4,07	23,7	0,14	0,65	disease	0,84	disease	0,89	disease	0,79	disease	0,75	5	deleterious	1	neutral	0,07	deleterious	5	deleterious	0,83	low_impact	-1,5	low_impact	-1,4	high_impact	2,46	0,5	0,9	48,23	8,39	N	0,43	N	0,99	polymorphism	0,9	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9829	9829	T	A	MI.7960	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	623	208	V	D	gTc/gAc	4,29	1	0	probably_damaging	1	neutral	0,08	neutral	1,15	deleterious	-9,71	deleterious	-6,66	high_impact	4,78	damaging	0,58	neutral	0,52	deleterious	4,59	24,4	0,01	0,35	disease	0,89	disease	0,91	disease	0,77	disease	0,84	7	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,88	low_impact	-3,78	medium_impact	-0,41	high_impact	3,1	0,15	0,8	73,95	11,68	P	0,59	P	0,94	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9829	9829	T	G	MI.7961	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	623	208	V	G	gTc/gGc	4,29	1	0	probably_damaging	1	neutral	0,3	neutral	1,16	deleterious	-8,37	deleterious	-6,65	high_impact	4,78	damaging	0,56	neutral	0,64	deleterious	3,95	23,6	0,02	0,35	disease	0,84	disease	0,86	disease	0,68	disease	0,77	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,02	high_impact	3,1	0,12	0,8	73,95	11,68	P	0,6	P	0,88	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9831	9831	A	T	MI.7962	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	625	209	I	F	Att/Ttt	-7,74	0	0	probably_damaging	0,97	neutral	0,54	neutral	2,07	neutral	-1,45	deleterious	-3,08	medium_impact	2,02	neutral	0,62	neutral	0,39	deleterious	3,87	23,5	0,13	0,4	neutral	0,48	disease	0,84	neutral	0,43	disease	0,53	1	neutral	0,96	neutral	0,29	deleterious	1	deleterious	0,77	low_impact	-2,34	medium_impact	0,23	medium_impact	0,63	0,58	0,8	73,95	11,02	N	0,26	N	0,94	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9831	9831	A	C	MI.7963	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	625	209	I	L	Att/Ctt	-7,74	0	0	possibly_damaging	0,82	neutral	0,88	neutral	2,31	neutral	0,08	neutral	-0,84	neutral_impact	0,42	neutral	0,68	neutral	0,76	deleterious	2,67	20,6	0,17	0,45	neutral	0,13	neutral	0,37	neutral	0,34	neutral	0,42	2	neutral	0,8	deleterious	0,53	neutral	-3	neutral	0,35	low_impact	-1,51	medium_impact	0,69	medium_impact	-0,81	0,54	0,8	73,95	11,02	N	0,27	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9831	9831	A	G	MI.7964	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	625	209	I	V	Att/Gtt	-7,74	0	0	possibly_damaging	0,63	neutral	0,81	neutral	2,27	neutral	-0,57	neutral	-0,82	medium_impact	2,4	neutral	0,66	neutral	0,45	deleterious	3,12	22,6	0,35	0,5	neutral	0,17	disease	0,5	disease	0,55	neutral	0,45	1	neutral	0,55	deleterious	0,59	NA	0	neutral	0,31	low_impact	-1,09	medium_impact	0,55	medium_impact	0,97	0,42	0,8	73,95	11,02	N	0,29	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9832	9832	T	C	MI.7965	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	626	209	I	T	aTt/aCt	5,68	1	0	probably_damaging	0,98	neutral	0,48	neutral	2,08	neutral	-0,23	deleterious	-4,03	low_impact	1,79	neutral	0,68	neutral	0,45	deleterious	3,49	23,1	0,06	0,35	neutral	0,26	disease	0,76	disease	0,58	disease	0,67	3	deleterious	0,98	neutral	0,25	neutral	-2	deleterious	0,72	low_impact	-2,51	medium_impact	0,17	medium_impact	0,42	0,3	0,8	73,95	11,02	N	0,43	N	0,91	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9832	9832	T	G	MI.7966	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	626	209	I	S	aTt/aGt	5,68	1	0	probably_damaging	0,98	neutral	0,37	neutral	2,07	neutral	-1,91	deleterious	-4,86	medium_impact	2,52	neutral	0,66	neutral	0,44	deleterious	4,38	24,1	0,04	0,35	disease	0,51	disease	0,87	disease	0,59	disease	0,71	4	deleterious	0,98	neutral	0,2	deleterious	1	deleterious	0,81	low_impact	-2,51	medium_impact	0,06	medium_impact	1,08	0,24	0,8	73,95	11,02	N	0,44	N	0,93	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9832	9832	T	A	MI.7967	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	626	209	I	N	aTt/aAt	5,68	1	0	probably_damaging	1	neutral	0,24	neutral	2,04	deleterious	-3,81	deleterious	-5,82	high_impact	3,99	neutral	0,61	neutral	0,37	deleterious	4,53	24,3	0,09	0,4	disease	0,68	disease	0,87	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	-0,09	high_impact	2,39	0,26	0,8	73,95	11,02	P	0,55	P	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9833	9833	T	G	MI.7968	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	627	209	I	M	atT/atG	7,53	1	0,01	probably_damaging	0,99	neutral	0,21	neutral	2,12	neutral	-2,43	neutral	-1,47	low_impact	1,42	neutral	0,71	neutral	0,73	deleterious	2,27	17,95	0,25	0,45	neutral	0,46	disease	0,53	neutral	0,39	neutral	0,47	1	deleterious	0,99	neutral	0,11	neutral	-2	deleterious	0,7	low_impact	-2,81	medium_impact	-0,14	medium_impact	0,09	0,52	0,8	73,95	11,02	P	0,53	P	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9833	9833	T	A	MI.7969	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	627	209	I	M	atT/atA	7,53	1	0,01	probably_damaging	0,99	neutral	0,21	neutral	2,12	neutral	-2,43	neutral	-1,47	low_impact	1,42	neutral	0,71	neutral	0,73	deleterious	2,59	20,1	0,25	0,45	neutral	0,46	disease	0,53	neutral	0,39	neutral	0,47	1	deleterious	0,99	neutral	0,11	neutral	-2	deleterious	0,7	low_impact	-2,81	medium_impact	-0,14	medium_impact	0,09	0,52	0,8	73,95	11,02	N	0,51	P	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8900	8900	T	A	MI.797	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	374	125	L	Q	cTa/cAa	-0,57	0	0	probably_damaging	0,9	deleterious	0	neutral	4,08	deleterious	-5,11	deleterious	-5,43	high_impact	4,15	damaging	0,58	neutral	0,48	deleterious	4,01	23,6	0,16	0,65	disease	0,85	disease	0,85	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,81	low_impact	-1,66	low_impact	-1,4	high_impact	2,46	0,58	0,9	48,23	8,39	N	0,33	N	0,98	polymorphism	0,92	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9834	9834	A	C	MI.7970	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	628	210	I	L	Att/Ctt	-1,03	0,05	0	possibly_damaging	0,82	neutral	0,56	neutral	2,19	neutral	-0,75	neutral	-1,9	medium_impact	2,19	damaging	0,59	damaging	0,04	deleterious	3,93	23,5	0,17	0,45	neutral	0,16	disease	0,73	disease	0,54	disease	0,59	2	neutral	0,8	neutral	0,37	NA	0	neutral	0,41	low_impact	-1,51	medium_impact	0,25	medium_impact	0,78	0,48	0,8	73,18	11,43	N	0,22	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9834	9834	A	T	MI.7971	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	628	210	I	F	Att/Ttt	-1,03	0,05	0	probably_damaging	0,97	neutral	0,65	neutral	2,03	neutral	-2,51	deleterious	-3,8	medium_impact	2,85	damaging	0,59	damaging	0,02	deleterious	3,86	23,5	0,12	0,4	neutral	0,27	disease	0,87	disease	0,61	disease	0,71	4	neutral	0,96	neutral	0,34	deleterious	1	deleterious	0,75	low_impact	-2,34	medium_impact	0,35	medium_impact	1,37	0,47	0,8	73,18	11,43	N	0,2	N	0,94	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9834	9834	A	G	MI.7972	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	628	210	I	V	Att/Gtt	-1,03	0,05	0	possibly_damaging	0,63	neutral	0,48	neutral	2,32	neutral	0	neutral	-0,94	low_impact	1,49	damaging	0,5	damaging	0,2	deleterious	3,15	22,6	0,33	0,5	neutral	0,14	neutral	0,31	neutral	0,37	neutral	0,37	3	neutral	0,61	neutral	0,43	neutral	-3	neutral	0,32	low_impact	-1,09	medium_impact	0,17	medium_impact	0,15	0,39	0,8	73,18	11,43	N	0,36	N	0,62	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9835	9835	T	G	MI.7973	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	629	210	I	S	aTt/aGt	6,84	1	0	probably_damaging	0,98	neutral	0,28	neutral	2,01	deleterious	-3,16	deleterious	-5,7	high_impact	3,63	neutral	0,64	damaging	0,06	deleterious	4,32	24	0,04	0,35	neutral	0,37	disease	0,88	disease	0,6	disease	0,71	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,8	low_impact	-2,51	medium_impact	-0,04	high_impact	2,07	0,22	0,8	73,18	11,43	N	0,45	N	0,93	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9835	9835	T	A	MI.7974	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	629	210	I	N	aTt/aAt	6,84	1	0	probably_damaging	1	neutral	0,11	neutral	1,99	deleterious	-4,26	deleterious	-6,65	high_impact	3,77	neutral	0,61	damaging	0,02	deleterious	4,36	24,1	0,09	0,4	disease	0,55	disease	0,88	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,33	high_impact	2,2	0,24	0,8	73,18	11,43	N	0,45	N	0,97	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9835	9835	T	C	MI.7975	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	629	210	I	T	aTt/aCt	6,84	1	0	probably_damaging	0,98	neutral	0,31	neutral	2,03	neutral	-2,63	deleterious	-4,74	medium_impact	2,66	damaging	0,59	damaging	0,02	deleterious	3,41	23	0,09	0,35	neutral	0,32	disease	0,8	disease	0,57	disease	0,66	3	deleterious	0,99	neutral	0,17	deleterious	1	deleterious	0,76	low_impact	-2,51	medium_impact	-0,01	medium_impact	1,2	0,23	0,8	73,18	11,43	N	0,37	N	0,91	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9836	9836	T	A	MI.7976	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	630	210	I	M	atT/atA	4,76	1	0	probably_damaging	0,99	neutral	0,16	neutral	2,05	neutral	-2,14	deleterious	-2,85	medium_impact	2,33	neutral	0,6	damaging	0,03	deleterious	3,74	23,3	0,2	0,45	neutral	0,31	disease	0,65	disease	0,52	neutral	0,45	1	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,7	low_impact	-2,81	medium_impact	-0,22	medium_impact	0,91	0,49	0,8	73,18	11,43	N	0,41	N	0,66	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9836	9836	T	G	MI.7977	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	630	210	I	M	atT/atG	4,76	1	0	probably_damaging	0,99	neutral	0,16	neutral	2,05	neutral	-2,14	deleterious	-2,85	medium_impact	2,33	neutral	0,6	damaging	0,03	deleterious	3,49	23,1	0,2	0,45	neutral	0,31	disease	0,65	disease	0,52	neutral	0,45	1	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,7	low_impact	-2,81	medium_impact	-0,22	medium_impact	0,91	0,49	0,8	73,18	11,43	N	0,4	N	0,66	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9837	9837	G	C	MI.7978	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	631	211	G	R	Ggc/Cgc	-1,03	0,03	0	probably_damaging	1	neutral	0,33	neutral	-0,4	deleterious	-10,57	deleterious	-7,61	high_impact	4,78	damaging	0,57	damaging	0,09	deleterious	3,99	23,6	0,02	0,35	disease	0,55	disease	0,92	disease	0,8	disease	0,82	6	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,78	medium_impact	0,02	high_impact	3,1	0,44	0,8	74,33	11,7	P	0,47	N	0,99	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9837	9837	G	A	MI.7979	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	631	211	G	S	Ggc/Agc	-1,03	0,03	0	probably_damaging	1	neutral	0,43	neutral	-0,39	deleterious	-9,08	deleterious	-5,71	high_impact	4,08	neutral	0,62	damaging	0,1	deleterious	4,27	24	0,03	0,35	neutral	0,48	disease	0,84	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	0,12	high_impact	2,47	0,38	0,8	74,33	11,7	N	0,29	N	0,85	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8902	8902	G	T	MI.798	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	376	126	A	S	Gcc/Tcc	-0,1	0,7	0	benign	0,39	neutral	0,65	neutral	4,44	neutral	0,44	neutral	-1,71	low_impact	0,84	neutral	0,81	neutral	0,57	deleterious	3,68	23,3	0,47	0,65	neutral	0,3	disease	0,63	neutral	0,28	neutral	0,34	3	neutral	0,32	deleterious	0,63	neutral	-6	deleterious	0,45	medium_impact	-0,57	medium_impact	0,44	medium_impact	-0,38	0,91	0,95	50,44	8,66	N	0,22	N	0,65	polymorphism	0,98	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9837	9837	G	T	MI.7980	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	631	211	G	C	Ggc/Tgc	-1,03	0,03	0	probably_damaging	1	neutral	0,2	neutral	-0,4	deleterious	-12,01	deleterious	-8,56	high_impact	4,78	damaging	0,54	damaging	0,09	deleterious	4,21	23,9	0,02	0,35	disease	0,83	disease	0,92	disease	0,72	disease	0,79	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,78	medium_impact	-0,15	high_impact	3,1	0,11	0,8	74,33	11,7	N	0,42	N	0,98	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9838	9838	G	A	MI.7981	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	632	211	G	D	gGc/gAc	9,15	1	0	probably_damaging	1	neutral	0,19	neutral	-0,38	deleterious	-8,46	deleterious	-6,66	high_impact	4,78	damaging	0,54	damaging	0,13	deleterious	3,91	23,5	0,02	0,35	disease	0,53	disease	0,9	disease	0,79	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	-0,17	high_impact	3,1	0,14	0,8	74,33	11,7	P	0,62	P	0,98	polymorphism	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9838	9838	G	C	MI.7982	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	632	211	G	A	gGc/gCc	9,15	1	0	probably_damaging	1	neutral	0,48	neutral	-0,36	deleterious	-7,88	deleterious	-5,71	high_impact	4,43	neutral	0,64	neutral	0,28	deleterious	3,19	22,7	0,03	0,35	neutral	0,46	disease	0,75	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	0,17	high_impact	2,79	0,31	0,8	74,33	11,7	P	0,52	P	0,3	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9838	9838	G	T	MI.7983	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	632	211	G	V	gGc/gTc	9,15	1	0	probably_damaging	1	neutral	0,54	neutral	-0,39	deleterious	-9,8	deleterious	-8,56	high_impact	4,43	damaging	0,52	damaging	0,14	deleterious	3,89	23,5	0,02	0,35	disease	0,61	disease	0,92	disease	0,74	disease	0,79	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	0,23	high_impact	2,79	0,17	0,8	74,33	11,7	P	0,51	P	0,97	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9840	9840	T	C	MI.7984	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	634	212	S	P	Tca/Cca	-6,81	0	0	probably_damaging	1	neutral	0,2	neutral	2,51	neutral	-1,99	deleterious	-2,59	medium_impact	3,48	damaging	0,58	neutral	0,38	deleterious	4,06	23,7	0,06	0,35	neutral	0,44	disease	0,92	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,83	low_impact	-3,78	medium_impact	-0,15	medium_impact	1,94	0,25	0,8	19,92	24,09	N	0,35	N	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9840	9840	T	G	MI.7985	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	634	212	S	A	Tca/Gca	-6,81	0	0	probably_damaging	0,98	neutral	0,51	neutral	2,59	neutral	1,2	neutral	-1,4	low_impact	1,57	neutral	0,6	neutral	0,76	deleterious	3,66	23,2	0,27	0,45	neutral	0,15	disease	0,58	neutral	0,47	neutral	0,45	1	neutral	0,97	neutral	0,27	neutral	-2	deleterious	0,62	low_impact	-2,51	medium_impact	0,2	medium_impact	0,22	0,43	0,8	19,92	24,09	N	0,32	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9840	9840	T	A	MI.7986	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	634	212	S	T	Tca/Aca	-6,81	0	0	probably_damaging	0,96	neutral	0,4	neutral	2,68	neutral	1,3	neutral	2,2	neutral_impact	-0,57	neutral	0,69	neutral	0,9	neutral	1,22	11,83	0,32	0,5	neutral	0,15	neutral	0,08	neutral	0,26	neutral	0,23	5	neutral	0,96	neutral	0,22	neutral	-2	deleterious	0,61	low_impact	-2,21	medium_impact	0,09	low_impact	-1,69	0,41	0,8	19,92	24,09	N	0,39	N	0,63	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9841	9841	C	G	MI.7987	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	635	212	S	W	tCa/tGa	1,75	0,96	0	probably_damaging	1	neutral	0,19	neutral	2,5	neutral	-2,75	deleterious	-3,77	medium_impact	3,48	neutral	0,62	neutral	0,43	deleterious	4,43	24,2	0,06	0,35	disease	0,67	disease	0,93	disease	0,63	disease	0,79	6	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,84	low_impact	-3,78	medium_impact	-0,17	medium_impact	1,94	0,12	0,8	19,92	24,09	N	0,42	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9841	9841	C	T	MI.7988	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	635	212	S	L	tCa/tTa	1,75	0,96	0	probably_damaging	1	neutral	0,66	neutral	2,81	neutral	2,45	deleterious	-2,82	low_impact	1,28	neutral	0,63	neutral	0,42	deleterious	4,57	24,4	0,09	0,4	neutral	0,11	disease	0,85	disease	0,56	disease	0,7	4	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,7	low_impact	-3,78	medium_impact	0,36	medium_impact	-0,04	0,31	0,8	19,92	24,09	N	0,33	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9843	9843	A	C	MI.7989	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	637	213	T	P	Act/Cct	-13,75	0	0	possibly_damaging	0,48	neutral	0,12	neutral	2,5	neutral	-2,17	deleterious	-4	medium_impact	3,23	damaging	0,56	neutral	0,34	deleterious	3,5	23,1	0,05	0,35	neutral	0,45	disease	0,86	disease	0,58	disease	0,75	5	neutral	0,87	neutral	0,32	NA	0	deleterious	0,66	medium_impact	-0,84	medium_impact	-0,3	medium_impact	1,71	0,23	0,8	76,25	9,77	N	0,35	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8902	8902	G	C	MI.799	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	376	126	A	P	Gcc/Ccc	-0,1	0,7	0	possibly_damaging	0,83	deleterious	0,04	neutral	4,27	neutral	-2,55	deleterious	-3,6	high_impact	3,8	neutral	0,71	neutral	0,35	deleterious	3,83	23,4	0,15	0,65	disease	0,8	disease	0,91	disease	0,72	disease	0,74	5	neutral	0,98	neutral	0,11	deleterious	5	deleterious	0,86	low_impact	-1,41	medium_impact	-0,49	high_impact	2,16	0,73	0,9	50,44	8,66	N	0,36	N	0,95	polymorphism	0,85	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9843	9843	A	T	MI.7990	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	637	213	T	S	Act/Tct	-13,75	0	0	benign	0,06	neutral	0,46	neutral	2,53	neutral	-1,02	neutral	-1,69	neutral_impact	0,65	neutral	0,69	neutral	0,74	deleterious	0,26	5,28	0,37	0,5	neutral	0,22	neutral	0,34	neutral	0,3	neutral	0,45	1	neutral	0,49	deleterious	0,7	neutral	-6	neutral	0,18	medium_impact	0,29	medium_impact	0,15	medium_impact	-0,6	0,38	0,8	76,25	9,77	N	0,45	N	0,34	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9843	9843	A	G	MI.7991	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	637	213	T	A	Act/Gct	-13,75	0	0	benign	0,03	neutral	0,31	neutral	2,58	neutral	0,52	deleterious	-2,56	low_impact	1,12	neutral	0,73	neutral	0,66	neutral	1,66	14,19	0,26	0,45	neutral	0,15	disease	0,5	neutral	0,33	neutral	0,44	1	neutral	0,67	deleterious	0,64	neutral	-6	neutral	0,15	medium_impact	0,6	medium_impact	-0,01	medium_impact	-0,18	0,24	0,8	76,25	9,77	N	0,43	N	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9844	9844	C	A	MI.7992	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	638	213	T	N	aCt/aAt	-0,33	0	0	benign	0,39	neutral	0,18	neutral	2,5	neutral	-2,4	deleterious	-3,11	medium_impact	2,68	neutral	0,62	neutral	0,39	deleterious	3,7	23,3	0,27	0,45	neutral	0,39	disease	0,71	disease	0,54	disease	0,68	4	neutral	0,79	neutral	0,4	neutral	-3	neutral	0,41	medium_impact	-0,68	medium_impact	-0,18	medium_impact	1,22	0,38	0,8	76,25	9,77	N	0,35	N	0,87	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9844	9844	C	G	MI.7993	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	638	213	T	S	aCt/aGt	-0,33	0	0	benign	0,06	neutral	0,46	neutral	2,53	neutral	-1,02	neutral	-1,69	neutral_impact	0,65	neutral	0,69	neutral	0,74	deleterious	0,4	6,59	0,37	0,5	neutral	0,22	neutral	0,34	neutral	0,3	neutral	0,45	1	neutral	0,49	deleterious	0,7	neutral	-6	neutral	0,18	medium_impact	0,29	medium_impact	0,15	medium_impact	-0,6	0,38	0,8	76,25	9,77	N	0,41	N	0,34	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9844	9844	C	T	MI.7994	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	638	213	T	I	aCt/aTt	-0,33	0	0	benign	0,18	neutral	0,47	neutral	2,77	neutral	1,97	deleterious	-3,29	neutral_impact	-0,48	neutral	0,68	neutral	0,68	neutral	1,14	11,42	0,12	0,4	neutral	0,12	neutral	0,4	neutral	0,3	neutral	0,44	1	neutral	0,44	deleterious	0,65	neutral	-6	neutral	0,31	medium_impact	-0,23	medium_impact	0,16	low_impact	-1,61	0,49	0,8	76,25	9,77	N	0,32	N	0,85	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9846	9846	T	A	MI.7995	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	640	214	F	I	Ttc/Atc	-7,74	0	0	probably_damaging	0,97	neutral	0,55	neutral	2,09	neutral	-0,49	deleterious	-5,7	medium_impact	3	neutral	0,69	damaging	0,02	deleterious	4,57	24,4	0,16	0,45	neutral	0,23	disease	0,88	disease	0,63	disease	0,71	4	neutral	0,96	neutral	0,29	deleterious	1	deleterious	0,75	low_impact	-2,34	medium_impact	0,24	medium_impact	1,51	0,3	0,8	74,33	11,72	N	0,24	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9846	9846	T	C	MI.7996	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	640	214	F	L	Ttc/Ctc	-7,74	0	0	probably_damaging	0,95	neutral	0,98	neutral	2,18	neutral	-0,13	deleterious	-5,7	medium_impact	2,37	neutral	0,65	damaging	0,03	deleterious	4,23	23,9	0,17	0,45	neutral	0,1	disease	0,85	disease	0,6	disease	0,66	3	neutral	0,94	deleterious	0,52	deleterious	1	deleterious	0,71	low_impact	-2,11	medium_impact	1,16	medium_impact	0,94	0,52	0,8	74,33	11,72	N	0,17	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9846	9846	T	G	MI.7997	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	640	214	F	V	Ttc/Gtc	-7,74	0	0	probably_damaging	0,98	neutral	0,34	neutral	2,1	neutral	-0,54	deleterious	-6,65	high_impact	3,71	neutral	0,66	damaging	0,02	deleterious	4,28	24	0,13	0,4	neutral	0,17	disease	0,92	disease	0,64	disease	0,72	4	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,75	low_impact	-2,51	medium_impact	0,03	high_impact	2,14	0,35	0,8	74,33	11,72	N	0,29	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9847	9847	T	A	MI.7998	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	641	214	F	Y	tTc/tAc	5,68	1	0	probably_damaging	0,95	neutral	0,38	neutral	2,07	neutral	-2,39	deleterious	-2,85	medium_impact	3,1	neutral	0,69	damaging	0,03	deleterious	4,36	24,1	0,23	0,45	neutral	0,28	disease	0,87	disease	0,65	disease	0,71	4	neutral	0,95	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-2,11	medium_impact	0,07	medium_impact	1,6	0,44	0,8	74,33	11,72	N	0,49	N	0,8	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9847	9847	T	C	MI.7999	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	641	214	F	S	tTc/tCc	5,68	1	0	probably_damaging	0,99	neutral	0,35	neutral	2,05	neutral	-2,09	deleterious	-7,6	high_impact	3,55	damaging	0,58	damaging	0,03	deleterious	4,35	24,1	0,06	0,35	neutral	0,37	disease	0,89	disease	0,62	disease	0,71	4	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-2,81	medium_impact	0,04	medium_impact	2	0,3	0,8	74,33	11,72	N	0,42	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8530	8530	A	C	MI.8	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	4	2	N	H	Aac/Cac	7,3	1	0	probably_damaging	0,99	deleterious	0,03	neutral	4,61	neutral	-1,76	deleterious	-3,06	medium_impact	2,6	neutral	0,89	neutral	0,39	deleterious	4,07	23,7	0,65	0,7	disease	0,71	neutral	0,28	neutral	0,14	disease	0,59	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,69	low_impact	-2,65	medium_impact	-0,56	medium_impact	1,13	0,3	0,9	41,59	7,23	P	0,62	P	0,98	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8561	8561	C	A	MI.80	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	35	12	P	H	cCc/cAc	7,3	1	0	probably_damaging	1	neutral	0,1	neutral	4,6	neutral	-1,03	deleterious	-7,84	medium_impact	3,02	neutral	0,64	damaging	0,07	deleterious	3,8	23,4	0,38	0,65	disease	0,7	disease	0,87	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	-0,25	medium_impact	1,49	0,62	0,9	50	8,94	P	0,5	N	0,67	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8902	8902	G	A	MI.800	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	376	126	A	T	Gcc/Acc	-0,1	0,7	0	benign	0,03	neutral	0,06	neutral	4,32	neutral	-0,9	deleterious	-2,86	medium_impact	2,44	neutral	0,85	neutral	0,58	deleterious	4,25	23,9	0,5	0,65	disease	0,55	disease	0,72	neutral	0,48	neutral	0,42	2	neutral	0,94	deleterious	0,52	neutral	-3	neutral	0,26	medium_impact	0,68	medium_impact	-0,38	medium_impact	0,99	0,8	0,9	50,44	8,66	N	0,33	N	0,54	polymorphism	0,95	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9847	9847	T	G	MI.8000	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	641	214	F	C	tTc/tGc	5,68	1	0	probably_damaging	1	neutral	0,09	neutral	2	deleterious	-3,55	deleterious	-7,6	high_impact	3,83	neutral	0,7	damaging	0,02	deleterious	4,21	23,9	0,07	0,35	disease	0,56	disease	0,91	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	-0,38	high_impact	2,25	0,19	0,8	74,33	11,72	N	0,46	N	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9848	9848	C	G	MI.8001	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	642	214	F	L	ttC/ttG	5,68	1	0	probably_damaging	0,95	neutral	0,98	neutral	2,18	neutral	-0,13	deleterious	-5,7	medium_impact	2,37	neutral	0,65	damaging	0,03	deleterious	4,54	24,3	0,17	0,45	neutral	0,1	disease	0,85	disease	0,6	disease	0,66	3	neutral	0,94	deleterious	0,52	deleterious	1	deleterious	0,71	low_impact	-2,11	medium_impact	1,16	medium_impact	0,94	0,52	0,8	74,33	11,72	N	0,36	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9848	9848	C	A	MI.8002	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	642	214	F	L	ttC/ttA	5,68	1	0	probably_damaging	0,95	neutral	0,98	neutral	2,18	neutral	-0,13	deleterious	-5,7	medium_impact	2,37	neutral	0,65	damaging	0,03	deleterious	4,87	24,9	0,17	0,45	neutral	0,1	disease	0,85	disease	0,6	disease	0,66	3	neutral	0,94	deleterious	0,52	deleterious	1	deleterious	0,71	low_impact	-2,11	medium_impact	1,16	medium_impact	0,94	0,52	0,8	74,33	11,72	N	0,36	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9849	9849	C	T	MI.8003	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	643	215	L	F	Ctc/Ttc	-1,72	0	0	probably_damaging	0,99	neutral	0,67	neutral	1,7	deleterious	-3,27	deleterious	-3,74	medium_impact	2,56	damaging	0,55	damaging	0,02	deleterious	4,11	23,8	0,12	0,4	neutral	0,45	disease	0,82	disease	0,62	disease	0,69	4	deleterious	0,99	neutral	0,34	deleterious	1	deleterious	0,81	low_impact	-2,81	medium_impact	0,37	medium_impact	1,11	0,38	0,8	74,33	11,66	N	0,18	N	0,95	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9849	9849	C	A	MI.8004	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	643	215	L	I	Ctc/Atc	-1,72	0	0	probably_damaging	0,98	neutral	0,25	neutral	1,77	neutral	-2,16	neutral	-1,78	low_impact	1,6	damaging	0,46	damaging	0,07	deleterious	4,25	23,9	0,24	0,45	neutral	0,18	disease	0,7	neutral	0,39	neutral	0,5	0	deleterious	0,99	neutral	0,14	neutral	-2	deleterious	0,71	low_impact	-2,51	medium_impact	-0,08	medium_impact	0,25	0,42	0,8	74,33	11,66	N	0,31	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9849	9849	C	G	MI.8005	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	643	215	L	V	Ctc/Gtc	-1,72	0	0	probably_damaging	0,95	neutral	0,46	neutral	1,78	neutral	-2,53	deleterious	-2,73	high_impact	4,19	damaging	0,52	damaging	0,01	deleterious	3,58	23,2	0,15	0,4	neutral	0,27	disease	0,78	disease	0,63	disease	0,68	4	neutral	0,95	neutral	0,26	deleterious	2	deleterious	0,73	low_impact	-2,11	medium_impact	0,15	high_impact	2,57	0,46	0,8	74,33	11,66	N	0,31	N	0,81	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9850	9850	T	A	MI.8006	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	644	215	L	H	cTc/cAc	0,13	0,01	0	probably_damaging	1	neutral	0,21	neutral	1,67	deleterious	-5,54	deleterious	-6,59	high_impact	4,54	damaging	0,55	damaging	0,02	deleterious	4,27	24	0,04	0,35	disease	0,58	disease	0,88	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,14	high_impact	2,89	0,24	0,8	74,33	11,66	N	0,41	N	0,97	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9850	9850	T	C	MI.8007	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	644	215	L	P	cTc/cCc	0,13	0,01	0	probably_damaging	1	neutral	0,05	neutral	1,67	deleterious	-5,59	deleterious	-6,6	high_impact	3,98	damaging	0,54	damaging	0,03	deleterious	4,05	23,7	0,02	0,35	disease	0,6	disease	0,88	disease	0,73	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	-0,54	high_impact	2,38	0,39	0,8	74,33	11,66	N	0,31	N	0,99	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9850	9850	T	G	MI.8008	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	644	215	L	R	cTc/cGc	0,13	0,01	0	probably_damaging	1	neutral	0,25	neutral	1,69	deleterious	-4,99	deleterious	-5,67	high_impact	4,54	neutral	0,66	damaging	0,02	deleterious	4,33	24	0,02	0,35	neutral	0,45	disease	0,93	disease	0,73	disease	0,83	7	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,87	low_impact	-3,78	medium_impact	-0,08	high_impact	2,89	0,12	0,8	74,33	11,66	N	0,42	N	0,99	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9852	9852	A	G	MI.8009	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	646	216	T	A	Act/Gct	-13,29	0	0	benign	0	neutral	0,31	neutral	2,66	neutral	1,06	neutral	-0,5	neutral_impact	-0,44	neutral	0,73	neutral	0,85	neutral	-0,5	0,22	0,25	0,45	neutral	0,12	neutral	0,17	neutral	0,24	neutral	0,26	5	neutral	0,69	deleterious	0,66	neutral	-6	neutral	0,08	high_impact	2,05	medium_impact	-0,01	low_impact	-1,58	0,34	0,8	19,92	32,03	N	0,45	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8903	8903	C	G	MI.801	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	377	126	A	G	gCc/gGc	4,29	0,99	0	possibly_damaging	0,47	neutral	0,47	neutral	4,32	neutral	-1	neutral	-0,45	neutral_impact	0,48	neutral	0,77	neutral	0,59	neutral	1,61	13,91	0,35	0,65	neutral	0,33	neutral	0,16	neutral	0,26	neutral	0,27	5	neutral	0,5	deleterious	0,5	neutral	-3	deleterious	0,47	medium_impact	-0,71	medium_impact	0,26	medium_impact	-0,69	0,81	0,9	50,44	8,66	N	0,5	N	0,68	polymorphism	0,85	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9852	9852	A	T	MI.8010	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	646	216	T	S	Act/Tct	-13,29	0	0	benign	0	neutral	0,28	neutral	2,56	neutral	-0,72	neutral	-0,91	neutral_impact	0,16	neutral	0,73	neutral	0,81	deleterious	0,2	4,7	0,42	0,55	neutral	0,18	neutral	0,25	neutral	0,22	neutral	0,42	2	neutral	0,72	deleterious	0,64	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	-0,04	low_impact	-1,04	0,58	0,8	19,92	32,03	N	0,55	P	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9852	9852	A	C	MI.8011	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	646	216	T	P	Act/Cct	-13,29	0	0	benign	0,15	deleterious	0,04	neutral	2,51	neutral	-2,73	neutral	-2,32	medium_impact	2,6	damaging	0,58	neutral	0,31	deleterious	1,88	15,47	0,05	0,35	neutral	0,43	disease	0,78	neutral	0,49	disease	0,65	3	neutral	0,96	neutral	0,45	deleterious	1	neutral	0,31	medium_impact	-0,14	medium_impact	-0,6	medium_impact	1,15	0,33	0,8	19,92	32,03	N	0,36	N	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9853	9853	C	A	MI.8012	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	647	216	T	N	aCt/aAt	-1,95	0	0	benign	0,05	neutral	0,16	neutral	2,51	neutral	-2,36	neutral	-2,06	medium_impact	2,25	neutral	0,7	neutral	0,54	deleterious	1,83	15,19	0,24	0,45	neutral	0,34	disease	0,52	neutral	0,36	neutral	0,48	1	neutral	0,83	deleterious	0,56	neutral	-3	neutral	0,16	medium_impact	0,37	medium_impact	-0,22	medium_impact	0,83	0,54	0,8	19,92	32,03	N	0,46	N	0,56	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9853	9853	C	G	MI.8013	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	647	216	T	S	aCt/aGt	-1,95	0	0	benign	0	neutral	0,28	neutral	2,56	neutral	-0,72	neutral	-0,91	neutral_impact	0,16	neutral	0,73	neutral	0,81	deleterious	0,4	6,59	0,42	0,55	neutral	0,18	neutral	0,25	neutral	0,22	neutral	0,42	2	neutral	0,72	deleterious	0,64	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	-0,04	low_impact	-1,04	0,58	0,8	19,92	32,03	N	0,5	N	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9853	9853	C	T	MI.8014	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	647	216	T	I	aCt/aTt	-1,95	0	0	benign	0	neutral	0,24	neutral	2,64	neutral	0,76	neutral	1,14	neutral_impact	-0,48	neutral	0,78	neutral	0,98	neutral	-0,29	0,69	0,11	0,4	neutral	0,11	neutral	0,33	neutral	0,21	neutral	0,43	2	neutral	0,76	deleterious	0,62	neutral	-6	neutral	0,09	high_impact	2,05	medium_impact	-0,09	low_impact	-1,61	0,58	0,8	19,92	32,03	N	0,37	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9855	9855	A	C	MI.8015	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	649	217	I	L	Atc/Ctc	-9,36	0	0	benign	0,01	neutral	1	neutral	2,25	neutral	-0,56	neutral	-1,6	low_impact	1,72	neutral	0,68	neutral	0,43	deleterious	2,05	16,54	0,19	0,45	neutral	0,15	disease	0,59	disease	0,53	disease	0,54	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,14	medium_impact	1,07	high_impact	1,9	medium_impact	0,36	0,43	0,8	22,99	32,68	N	0,29	N	0,16	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9855	9855	A	G	MI.8016	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	649	217	I	V	Atc/Gtc	-9,36	0	0	benign	0	neutral	0,59	neutral	2,58	neutral	1,16	neutral	0,4	neutral_impact	-0,7	neutral	0,74	neutral	0,99	neutral	-1,44	0	0,38	0,5	neutral	0,11	neutral	0,06	neutral	0,27	neutral	0,19	6	neutral	0,41	deleterious	0,8	neutral	-6	neutral	0,08	high_impact	2,05	medium_impact	0,28	low_impact	-1,81	0,37	0,8	22,99	32,68	N	0,34	N	0	polymorphism	1	0,01	rs201552272	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9855	9855	A	T	MI.8017	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	649	217	I	F	Atc/Ttc	-9,36	0	0	benign	0,16	neutral	0,63	neutral	2,15	neutral	-1,71	deleterious	-3,32	low_impact	1,6	neutral	0,62	neutral	0,42	deleterious	3,63	23,2	0,16	0,45	neutral	0,24	disease	0,77	disease	0,51	disease	0,54	1	neutral	0,25	deleterious	0,74	neutral	-6	neutral	0,29	medium_impact	-0,17	medium_impact	0,32	medium_impact	0,25	0,41	0,8	22,99	32,68	N	0,32	N	0,4	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9856	9856	T	A	MI.8018	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	650	217	I	N	aTc/aAc	-0,33	0	0	benign	0,12	neutral	0,08	neutral	2,1	deleterious	-3,45	deleterious	-4,9	medium_impact	3,44	neutral	0,64	neutral	0,36	deleterious	2,94	22	0,09	0,35	neutral	0,44	disease	0,82	disease	0,59	disease	0,75	5	neutral	0,91	deleterious	0,48	neutral	-3	neutral	0,31	medium_impact	-0,03	medium_impact	-0,41	medium_impact	1,9	0,19	0,8	22,99	32,68	N	0,4	N	0,5	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9856	9856	T	C	MI.8019	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	650	217	I	T	aTc/aCc	-0,33	0	0	benign	0	neutral	0,12	neutral	2,15	neutral	-1,78	neutral	-2,24	low_impact	1,19	neutral	0,75	neutral	0,93	deleterious	0,31	5,83	0,12	0,4	neutral	0,19	neutral	0,49	neutral	0,39	neutral	0,45	1	neutral	0,88	deleterious	0,56	neutral	-6	neutral	0,14	high_impact	2,05	medium_impact	-0,3	medium_impact	-0,12	0,2	0,8	22,99	32,68	N	0,47	N	0,23	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8903	8903	C	T	MI.802	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	377	126	A	V	gCc/gTc	4,29	0,99	0	benign	0,39	neutral	0,12	neutral	4,28	neutral	-2,11	deleterious	-3,31	medium_impact	3,1	neutral	0,8	neutral	0,53	deleterious	4,47	24,2	0,34	0,65	disease	0,58	disease	0,77	disease	0,6	disease	0,63	3	neutral	0,86	neutral	0,37	neutral	-3	deleterious	0,56	medium_impact	-0,57	medium_impact	-0,2	medium_impact	1,56	0,84	0,9	50,44	8,66	N	0,47	N	0,68	polymorphism	0,82	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9856	9856	T	G	MI.8020	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	650	217	I	S	aTc/aGc	-0,33	0	0	benign	0,07	neutral	0,25	neutral	2,12	neutral	-2,43	deleterious	-3,88	low_impact	1,85	neutral	0,63	neutral	0,43	deleterious	2,57	19,9	0,04	0,35	neutral	0,28	disease	0,77	disease	0,56	disease	0,68	4	neutral	0,72	deleterious	0,59	neutral	-6	neutral	0,21	medium_impact	0,22	medium_impact	-0,08	medium_impact	0,48	0,18	0,8	22,99	32,68	N	0,38	N	0,41	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9857	9857	C	A	MI.8021	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	651	217	I	M	atC/atA	2,44	0,1	0	benign	0,37	neutral	0,1	neutral	2,13	neutral	-2,33	neutral	-1,82	low_impact	1,71	neutral	0,68	neutral	0,7	deleterious	3,52	23,1	0,25	0,45	neutral	0,29	disease	0,5	neutral	0,49	neutral	0,47	1	neutral	0,88	neutral	0,37	neutral	-6	neutral	0,26	medium_impact	-0,64	medium_impact	-0,35	medium_impact	0,35	0,35	0,8	22,99	32,68	N	0,53	P	0,12	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9857	9857	C	G	MI.8022	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	651	217	I	M	atC/atG	2,44	0,1	0	benign	0,37	neutral	0,1	neutral	2,13	neutral	-2,33	neutral	-1,82	low_impact	1,71	neutral	0,68	neutral	0,7	deleterious	3,16	22,6	0,25	0,45	neutral	0,29	disease	0,5	neutral	0,49	neutral	0,47	1	neutral	0,88	neutral	0,37	neutral	-6	neutral	0,26	medium_impact	-0,64	medium_impact	-0,35	medium_impact	0,35	0,35	0,8	22,99	32,68	N	0,54	P	0,12	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9858	9858	T	C	MI.8023	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	652	218	C	R	Tgc/Cgc	-15,37	0	0	probably_damaging	1	neutral	0,49	neutral	2,5	neutral	-2,2	deleterious	-10,59	high_impact	3,58	neutral	0,72	damaging	0,03	deleterious	3,58	23,2	0,06	0,35	neutral	0,34	disease	0,96	disease	0,73	disease	0,86	7	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	0,18	high_impact	2,03	0,07	0,8	73,56	11,78	N	0,3	N	0,94	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9858	9858	T	A	MI.8024	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	652	218	C	S	Tgc/Agc	-15,37	0	0	probably_damaging	1	neutral	0,41	neutral	2,53	neutral	-1,07	deleterious	-8,62	low_impact	1,53	damaging	0,48	damaging	0,07	deleterious	3,6	23,2	0,08	0,35	neutral	0,24	disease	0,8	neutral	0,42	disease	0,51	0	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,76	low_impact	-3,78	medium_impact	0,1	medium_impact	0,19	0,41	0,8	73,56	11,78	N	0,32	N	0,86	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9858	9858	T	G	MI.8025	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	652	218	C	G	Tgc/Ggc	-15,37	0	0	probably_damaging	1	neutral	0,46	neutral	2,49	neutral	-1,76	deleterious	-10,56	medium_impact	2,65	damaging	0,53	damaging	0,05	deleterious	3,39	23	0,07	0,35	neutral	0,24	disease	0,91	neutral	0,48	disease	0,51	0	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,76	low_impact	-3,78	medium_impact	0,15	medium_impact	1,19	0,26	0,8	73,56	11,78	N	0,28	N	0,95	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9859	9859	G	T	MI.8026	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	653	218	C	F	tGc/tTc	5,68	1	0	probably_damaging	1	neutral	0,84	neutral	2,5	neutral	-1,26	deleterious	-9,73	high_impact	3,78	neutral	0,62	damaging	0,03	deleterious	4,04	23,7	0,08	0,35	neutral	0,26	disease	0,96	disease	0,63	disease	0,78	6	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	0,6	high_impact	2,21	0,27	0,8	73,56	11,78	N	0,4	N	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9859	9859	G	A	MI.8027	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	653	218	C	Y	tGc/tAc	5,68	1	0	probably_damaging	1	neutral	1	neutral	2,51	neutral	-1,34	deleterious	-9,72	high_impact	3,58	neutral	0,65	damaging	0,02	deleterious	3,74	23,3	0,07	0,35	neutral	0,21	disease	0,95	disease	0,65	disease	0,78	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,81	low_impact	-3,78	high_impact	1,9	high_impact	2,03	0,41	0,8	73,56	11,78	N	0,37	N	1	polymorphism	1	0,16	.	.	.	.	.	.	COSM1138444	.	.	.	.	.	.	.	.
chrM	9859	9859	G	C	MI.8028	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	653	218	C	S	tGc/tCc	5,68	1	0	probably_damaging	1	neutral	0,41	neutral	2,53	neutral	-1,07	deleterious	-8,62	low_impact	1,53	damaging	0,48	damaging	0,07	deleterious	3,31	22,9	0,08	0,35	neutral	0,24	disease	0,8	neutral	0,42	disease	0,51	0	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,76	low_impact	-3,78	medium_impact	0,1	medium_impact	0,19	0,41	0,8	73,56	11,78	N	0,4	N	0,86	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9860	9860	C	G	MI.8029	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	654	218	C	W	tgC/tgG	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	2,47	deleterious	-3,59	deleterious	-9,69	high_impact	4,12	neutral	0,69	damaging	0,03	deleterious	4,43	24,2	0,05	0,35	disease	0,58	disease	0,96	disease	0,69	disease	0,81	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,18	high_impact	2,51	0,27	0,8	73,56	11,78	N	0,47	N	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8903	8903	C	A	MI.803	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	377	126	A	D	gCc/gAc	4,29	0,99	0	possibly_damaging	0,77	deleterious	0,01	neutral	4,33	neutral	-0,73	deleterious	-3,84	medium_impact	3,44	neutral	0,78	neutral	0,42	deleterious	4,66	24,5	0,19	0,65	disease	0,68	disease	0,91	disease	0,65	disease	0,74	5	deleterious	0,99	neutral	0,12	deleterious	4	deleterious	0,79	low_impact	-1,25	medium_impact	-0,84	medium_impact	1,85	0,63	0,9	50,44	8,66	N	0,47	N	1	polymorphism	0,52	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9860	9860	C	A	MI.8030	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	654	218	C	W	tgC/tgA	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	2,47	deleterious	-3,59	deleterious	-9,69	high_impact	4,12	neutral	0,69	damaging	0,03	deleterious	4,74	24,6	0,05	0,35	disease	0,58	disease	0,96	disease	0,69	disease	0,81	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,18	high_impact	2,51	0,27	0,8	73,56	11,78	N	0,48	N	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9861	9861	T	C	MI.8031	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	655	219	F	L	Ttc/Ctc	-0,33	0	0	benign	0	neutral	1	neutral	2,81	neutral	1,43	neutral	2,72	neutral_impact	-1,69	neutral	0,69	neutral	0,95	neutral	-0,44	0,31	0,21	0,45	neutral	0,1	neutral	0,14	neutral	0,17	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,05	high_impact	1,9	low_impact	-2,7	0,69	0,85	21,46	37,53	N	0,48	N	0	polymorphism	1	0,01	rs878853060	Likely benign	not_provided	RCV000224068.1	MedGen	.	.	CPD	17,06	T9861C	AD	+	-	Reported	1
chrM	9861	9861	T	G	MI.8032	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	655	219	F	V	Ttc/Gtc	-0,33	0	0	benign	0,05	neutral	0,27	neutral	2,56	neutral	-0,17	neutral	0,19	low_impact	1,6	neutral	0,66	neutral	0,58	deleterious	2,4	18,81	0,11	0,4	neutral	0,15	disease	0,74	neutral	0,48	disease	0,55	1	neutral	0,71	deleterious	0,61	neutral	-6	neutral	0,15	medium_impact	0,37	medium_impact	-0,06	medium_impact	0,25	0,26	0,8	21,46	37,53	N	0,41	N	0,35	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9861	9861	T	A	MI.8033	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	655	219	F	I	Ttc/Atc	-0,33	0	0	benign	0,01	neutral	0,5	neutral	2,6	neutral	-0,09	neutral	1,09	low_impact	1,32	neutral	0,66	neutral	0,63	deleterious	2,62	20,3	0,14	0,4	neutral	0,15	disease	0,67	neutral	0,35	disease	0,51	0	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,15	medium_impact	1,07	medium_impact	0,19	medium_impact	0	0,35	0,8	21,46	37,53	N	0,34	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9862	9862	T	A	MI.8034	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	656	219	F	Y	tTc/tAc	-0,33	0	0	benign	0,09	neutral	0,54	neutral	2,53	neutral	-0,93	neutral	-1,11	low_impact	0,84	neutral	0,71	neutral	0,66	deleterious	2,66	20,5	0,19	0,45	neutral	0,27	disease	0,57	neutral	0,35	neutral	0,47	1	neutral	0,38	deleterious	0,73	neutral	-6	neutral	0,2	medium_impact	0,11	medium_impact	0,23	medium_impact	-0,43	0,58	0,8	21,46	37,53	N	0,31	N	0,42	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9862	9862	T	C	MI.8035	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	656	219	F	S	tTc/tCc	-0,33	0	0	benign	0,18	neutral	0,31	neutral	2,53	neutral	-1,56	neutral	-2,41	medium_impact	1,94	neutral	0,64	neutral	0,48	deleterious	2,81	21,4	0,04	0,35	neutral	0,27	disease	0,65	neutral	0,47	disease	0,52	0	neutral	0,63	deleterious	0,57	neutral	-3	neutral	0,31	medium_impact	-0,23	medium_impact	-0,01	medium_impact	0,56	0,17	0,8	21,46	37,53	N	0,41	N	0,68	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9862	9862	T	G	MI.8036	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	656	219	F	C	tTc/tGc	-0,33	0	0	possibly_damaging	0,67	neutral	0,5	neutral	2,48	neutral	-2,92	neutral	-1,58	low_impact	1,25	neutral	0,63	neutral	0,48	deleterious	4,16	23,8	0,05	0,35	neutral	0,47	disease	0,79	neutral	0,37	disease	0,65	3	neutral	0,64	neutral	0,42	neutral	-3	deleterious	0,6	low_impact	-1,17	medium_impact	0,19	medium_impact	-0,06	0,15	0,8	21,46	37,53	N	0,28	N	0,57	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9863	9863	C	G	MI.8037	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	657	219	F	L	ttC/ttG	7,53	0,96	0	benign	0	neutral	1	neutral	2,81	neutral	1,43	neutral	2,72	neutral_impact	-1,69	neutral	0,69	neutral	0,95	neutral	-0,2	1,07	0,21	0,45	neutral	0,1	neutral	0,14	neutral	0,17	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,05	high_impact	1,9	low_impact	-2,7	0,69	0,85	21,46	37,53	P	0,54	P	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9863	9863	C	A	MI.8038	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	657	219	F	L	ttC/ttA	7,53	0,96	0	benign	0	neutral	1	neutral	2,81	neutral	1,43	neutral	2,72	neutral_impact	-1,69	neutral	0,69	neutral	0,95	deleterious	0,16	4,22	0,21	0,45	neutral	0,1	neutral	0,14	neutral	0,17	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,05	high_impact	1,9	low_impact	-2,7	0,69	0,85	21,46	37,53	P	0,55	P	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9864	9864	A	C	MI.8039	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	658	220	I	L	Atc/Ctc	-11,21	0	0	benign	0,01	neutral	1	neutral	2,39	neutral	0,03	neutral	0,18	neutral_impact	-0,74	neutral	0,77	neutral	0,95	neutral	-0,67	0,09	0,17	0,45	neutral	0,14	neutral	0,16	neutral	0,11	neutral	0,28	5	neutral	0,01	deleterious	1	neutral	-6	neutral	0,09	medium_impact	1,07	high_impact	1,9	low_impact	-1,85	0,28	0,8	18,01	34,58	N	0,4	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8905	8905	C	A	MI.804	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	379	127	H	N	Cac/Aac	-6,35	0	0,01	probably_damaging	0,98	deleterious	0,02	neutral	3,76	neutral	-2,48	deleterious	-6,47	high_impact	3,86	damaging	0,56	neutral	0,4	deleterious	3,96	23,6	0,59	0,7	neutral	0,46	disease	0,83	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,78	low_impact	-2,36	medium_impact	-0,66	high_impact	2,21	0,5	0,9	50,44	8,73	N	0,41	N	0,98	disease_causing	0,65	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9864	9864	A	G	MI.8040	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	658	220	I	V	Atc/Gtc	-11,21	0	0	benign	0	neutral	0,29	neutral	2,34	neutral	-0,25	neutral	-0,49	neutral_impact	-0,34	neutral	0,77	neutral	0,83	deleterious	0,15	4,1	0,3	0,45	neutral	0,19	neutral	0,18	neutral	0,16	neutral	0,31	4	neutral	0,71	deleterious	0,65	neutral	-6	neutral	0,09	high_impact	2,05	medium_impact	-0,03	low_impact	-1,49	0,32	0,8	18,01	34,58	N	0,52	P	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9864	9864	A	T	MI.8041	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	658	220	I	F	Atc/Ttc	-11,21	0	0	benign	0,11	neutral	0,41	neutral	2,25	neutral	-1,27	neutral	-1,6	neutral_impact	-0,58	neutral	0,79	neutral	0,97	deleterious	0,78	9,35	0,14	0,4	neutral	0,23	neutral	0,39	neutral	0,13	neutral	0,44	1	neutral	0,53	deleterious	0,65	neutral	-6	neutral	0,15	medium_impact	0,01	medium_impact	0,1	low_impact	-1,7	0,32	0,8	18,01	34,58	N	0,45	N	0,14	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9865	9865	T	C	MI.8042	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	659	220	I	T	aTc/aCc	-7,51	0	0	benign	0	neutral	0,19	neutral	2,24	neutral	-1,79	deleterious	-2,6	low_impact	1,58	neutral	0,69	neutral	0,74	neutral	1,6	13,85	0,12	0,4	neutral	0,29	neutral	0,39	neutral	0,34	neutral	0,45	1	neutral	0,81	deleterious	0,6	neutral	-6	neutral	0,13	high_impact	2,05	medium_impact	-0,17	medium_impact	0,23	0,19	0,8	18,01	34,58	N	0,5	N	0,34	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9865	9865	T	A	MI.8043	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	659	220	I	N	aTc/aAc	-7,51	0	0	benign	0,05	neutral	0,15	neutral	2,2	deleterious	-3,38	deleterious	-4,12	low_impact	1,66	neutral	0,71	neutral	0,47	deleterious	2,78	21,3	0,09	0,35	neutral	0,5	disease	0,67	neutral	0,46	neutral	0,48	0	neutral	0,84	deleterious	0,55	neutral	-6	neutral	0,22	medium_impact	0,37	medium_impact	-0,24	medium_impact	0,31	0,15	0,8	18,01	34,58	N	0,37	N	0,57	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9865	9865	T	G	MI.8044	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	659	220	I	S	aTc/aGc	-7,51	0	0	benign	0	neutral	0,23	neutral	2,23	neutral	-2,21	deleterious	-3,22	low_impact	1,51	neutral	0,69	neutral	0,6	deleterious	2,48	19,35	0,04	0,35	neutral	0,25	disease	0,6	neutral	0,36	neutral	0,48	0	neutral	0,77	deleterious	0,62	neutral	-6	neutral	0,15	high_impact	2,05	medium_impact	-0,11	medium_impact	0,17	0,15	0,8	18,01	34,58	N	0,46	N	0,37	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9866	9866	C	G	MI.8045	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	660	220	I	M	atC/atG	3,83	0,39	0	benign	0,27	neutral	0,12	neutral	2,22	neutral	-2,08	neutral	-0,33	neutral_impact	0,21	neutral	0,76	neutral	0,96	deleterious	0,55	7,83	0,19	0,45	neutral	0,34	neutral	0,21	neutral	0,15	neutral	0,37	3	neutral	0,86	neutral	0,43	neutral	-6	neutral	0,18	medium_impact	-0,45	medium_impact	-0,3	medium_impact	-0,99	0,36	0,8	18,01	34,58	N	0,5	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9866	9866	C	A	MI.8046	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	660	220	I	M	atC/atA	3,83	0,39	0	benign	0,27	neutral	0,12	neutral	2,22	neutral	-2,08	neutral	-0,33	neutral_impact	0,21	neutral	0,76	neutral	0,96	neutral	0,97	10,47	0,19	0,45	neutral	0,34	neutral	0,21	neutral	0,15	neutral	0,37	3	neutral	0,86	neutral	0,43	neutral	-6	neutral	0,18	medium_impact	-0,45	medium_impact	-0,3	medium_impact	-0,99	0,36	0,8	18,01	34,58	N	0,5	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9867	9867	C	T	MI.8047	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	661	221	R	C	Cgc/Tgc	-7,04	0	0	benign	0,01	neutral	0,18	neutral	1,72	deleterious	-6,32	deleterious	-7,41	high_impact	4,14	neutral	0,67	damaging	0,02	deleterious	3,23	22,8	0,09	0,4	disease	0,8	disease	0,85	disease	0,75	disease	0,8	6	neutral	0,82	deleterious	0,59	neutral	-2	neutral	0,31	medium_impact	1,07	medium_impact	-0,18	high_impact	2,53	0,89	0,9	72,8	11,99	N	0,32	N	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9867	9867	C	G	MI.8048	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	661	221	R	G	Cgc/Ggc	-7,04	0	0	benign	0,28	neutral	0,33	neutral	1,76	deleterious	-4,21	deleterious	-6,46	high_impact	4,35	neutral	0,64	damaging	0,01	deleterious	4,16	23,8	0,05	0,35	neutral	0,48	disease	0,8	disease	0,74	disease	0,74	5	neutral	0,6	deleterious	0,53	neutral	-2	deleterious	0,52	medium_impact	-0,47	medium_impact	0,02	high_impact	2,72	0,28	0,8	72,8	11,99	N	0,37	N	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9867	9867	C	A	MI.8049	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	661	221	R	S	Cgc/Agc	-7,04	0	0	benign	0,17	neutral	0,4	neutral	1,79	deleterious	-3,37	deleterious	-5,56	high_impact	4,14	neutral	0,67	damaging	0,01	deleterious	4,39	24,1	0,05	0,35	neutral	0,32	disease	0,8	disease	0,69	disease	0,7	4	neutral	0,52	deleterious	0,62	neutral	-2	deleterious	0,49	medium_impact	-0,2	medium_impact	0,09	high_impact	2,53	0,31	0,8	72,8	11,99	N	0,33	N	0,88	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8905	8905	C	G	MI.805	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	379	127	H	D	Cac/Gac	-6,35	0	0,01	probably_damaging	0,99	deleterious	0,03	neutral	3,75	neutral	-2,97	deleterious	-8,32	high_impact	4,06	neutral	0,67	neutral	0,39	deleterious	3,9	23,5	0,32	0,65	disease	0,74	disease	0,83	disease	0,77	disease	0,72	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,82	low_impact	-2,65	medium_impact	-0,56	high_impact	2,38	0,46	0,9	50,44	8,73	N	0,41	N	1	disease_causing	0,86	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9868	9868	G	C	MI.8050	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	662	221	R	P	cGc/cCc	7,3	1	0	possibly_damaging	0,69	neutral	0,2	neutral	1,74	deleterious	-4,89	deleterious	-6,49	high_impact	3,8	neutral	0,62	damaging	0,03	deleterious	4,38	24,1	0,03	0,35	disease	0,57	disease	0,84	disease	0,82	disease	0,8	6	neutral	0,83	neutral	0,26	deleterious	1	deleterious	0,75	low_impact	-1,21	medium_impact	-0,15	high_impact	2,22	0,24	0,8	72,8	11,99	P	0,56	P	0,99	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9868	9868	G	A	MI.8051	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	662	221	R	H	cGc/cAc	7,3	1	0	possibly_damaging	0,58	neutral	0,54	neutral	1,75	deleterious	-4,44	deleterious	-4,63	high_impact	4,14	neutral	0,63	damaging	0,02	deleterious	4,5	24,3	0,14	0,4	disease	0,5	disease	0,8	disease	0,7	disease	0,72	4	neutral	0,54	deleterious	0,48	deleterious	1	deleterious	0,7	low_impact	-1,01	medium_impact	0,23	high_impact	2,53	0,96	1	72,8	11,99	P	0,55	P	1	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9868	9868	G	T	MI.8052	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	662	221	R	L	cGc/cTc	7,3	1	0	benign	0,05	neutral	0,66	neutral	1,76	deleterious	-3,98	deleterious	-6,49	high_impact	3,89	neutral	0,64	damaging	0,02	deleterious	2,87	21,7	0,06	0,35	neutral	0,35	disease	0,89	disease	0,7	disease	0,75	5	neutral	0,27	deleterious	0,81	neutral	-2	neutral	0,33	medium_impact	0,37	medium_impact	0,36	high_impact	2,3	0,09	0,8	72,8	11,99	N	0,48	N	1	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9870	9870	C	G	MI.8053	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	664	222	Q	E	Caa/Gaa	-8,66	0	0	probably_damaging	0,91	neutral	0,27	neutral	2,58	neutral	-0,2	neutral	-1,42	low_impact	1,82	damaging	0,53	damaging	0,07	deleterious	3,18	22,7	0,34	0,5	neutral	0,22	neutral	0,47	neutral	0,41	neutral	0,49	0	neutral	0,93	neutral	0,18	neutral	-2	deleterious	0,67	low_impact	-1,85	medium_impact	-0,06	medium_impact	0,45	0,42	0,8	78,16	10,52	N	0,32	N	0,95	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9870	9870	C	A	MI.8054	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	664	222	Q	K	Caa/Aaa	-8,66	0	0	probably_damaging	0,96	neutral	0,29	neutral	2,58	neutral	-0,24	neutral	-1,9	low_impact	1,91	damaging	0,52	damaging	0,04	deleterious	4,07	23,7	0,21	0,45	neutral	0,21	disease	0,62	neutral	0,41	neutral	0,49	0	neutral	0,97	neutral	0,17	neutral	-2	deleterious	0,69	low_impact	-2,21	medium_impact	-0,03	medium_impact	0,53	0,4	0,8	78,16	10,52	N	0,29	N	0,98	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9871	9871	A	C	MI.8055	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	665	222	Q	P	cAa/cCa	4,52	1	0	probably_damaging	0,99	neutral	0,2	neutral	2,58	neutral	-0,34	deleterious	-3,15	medium_impact	2,71	damaging	0,46	damaging	0,05	deleterious	3,47	23	0,05	0,35	neutral	0,39	disease	0,79	disease	0,53	disease	0,72	4	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,8	low_impact	-2,81	medium_impact	-0,15	medium_impact	1,25	0,28	0,8	78,16	10,52	N	0,43	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9871	9871	A	T	MI.8056	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	665	222	Q	L	cAa/cTa	4,52	1	0	probably_damaging	0,96	neutral	0,69	neutral	2,78	neutral	2,45	neutral	-2,32	neutral_impact	-0,42	neutral	0,61	neutral	0,31	deleterious	2,55	19,78	0,09	0,35	neutral	0,1	neutral	0,29	neutral	0,16	neutral	0,42	2	neutral	0,95	neutral	0,37	neutral	-2	deleterious	0,65	low_impact	-2,21	medium_impact	0,39	low_impact	-1,56	0,11	0,8	78,16	10,52	N	0,41	N	0,98	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9871	9871	A	G	MI.8057	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	665	222	Q	R	cAa/cGa	4,52	1	0	probably_damaging	0,98	neutral	0,38	neutral	2,58	neutral	-0,1	neutral	-1,67	medium_impact	2,71	damaging	0,48	damaging	0,05	deleterious	3,62	23,2	0,21	0,45	neutral	0,26	disease	0,61	neutral	0,44	disease	0,5	0	neutral	0,98	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-2,51	medium_impact	0,07	medium_impact	1,25	0,16	0,8	78,16	10,52	N	0,46	N	0,98	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9872	9872	A	C	MI.8058	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	666	222	Q	H	caA/caC	4,52	1	0	probably_damaging	0,99	neutral	0,54	neutral	2,59	neutral	0,07	neutral	-0,32	neutral_impact	-0,06	damaging	0,6	damaging	0,1	deleterious	2,15	17,18	0,21	0,45	neutral	0,32	neutral	0,23	neutral	0,18	neutral	0,44	1	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,7	low_impact	-2,81	medium_impact	0,23	low_impact	-1,24	0,57	0,8	78,16	10,52	N	0,42	N	0,98	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9872	9872	A	T	MI.8059	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	666	222	Q	H	caA/caT	4,52	1	0	probably_damaging	0,99	neutral	0,54	neutral	2,59	neutral	0,07	neutral	-0,32	neutral_impact	-0,06	damaging	0,6	damaging	0,1	deleterious	2,29	18,08	0,21	0,45	neutral	0,32	neutral	0,23	neutral	0,18	neutral	0,44	1	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,7	low_impact	-2,81	medium_impact	0,23	low_impact	-1,24	0,57	0,8	78,16	10,52	N	0,42	N	0,98	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8905	8905	C	T	MI.806	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	379	127	H	Y	Cac/Tac	-6,35	0	0,01	probably_damaging	0,98	neutral	0,13	neutral	3,84	neutral	-0,67	deleterious	-5,55	medium_impact	3,08	damaging	0,57	neutral	0,32	deleterious	3,77	23,4	0,59	0,7	disease	0,75	disease	0,84	disease	0,78	disease	0,72	4	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,83	low_impact	-2,36	medium_impact	-0,18	medium_impact	1,54	0,37	0,9	50,44	8,73	N	0,33	N	1	disease_causing	0,69	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9873	9873	C	A	MI.8060	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	667	223	L	M	Cta/Ata	2,9	0,98	0	probably_damaging	1	neutral	0,23	neutral	2,19	neutral	-1,59	neutral	-0,27	neutral_impact	0,78	neutral	0,75	neutral	0,95	deleterious	2,76	21,1	0,29	0,45	neutral	0,19	neutral	0,12	neutral	0,12	neutral	0,29	4	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,62	low_impact	-3,78	medium_impact	-0,11	medium_impact	-0,48	0,53	0,8	20,69	26,81	P	0,61	P	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9873	9873	C	G	MI.8061	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	667	223	L	V	Cta/Gta	2,9	0,98	0	probably_damaging	0,96	neutral	0,5	neutral	2,29	neutral	-0,91	neutral	-0,9	low_impact	1,7	neutral	0,79	neutral	0,93	deleterious	2,09	16,81	0,26	0,45	neutral	0,14	neutral	0,26	neutral	0,14	neutral	0,42	2	neutral	0,95	neutral	0,27	neutral	-2	deleterious	0,6	low_impact	-2,21	medium_impact	0,19	medium_impact	0,34	0,47	0,8	20,69	26,81	N	0,47	N	0,56	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9874	9874	T	C	MI.8062	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	668	223	L	P	cTa/cCa	-2,88	0	0	probably_damaging	1	neutral	0,2	neutral	2,13	deleterious	-4	deleterious	-4,1	medium_impact	3,08	damaging	0,58	damaging	0,04	deleterious	4,11	23,8	0,04	0,35	disease	0,52	disease	0,76	neutral	0,47	disease	0,56	1	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,81	low_impact	-3,78	medium_impact	-0,15	medium_impact	1,58	0,14	0,8	20,69	26,81	N	0,26	N	0,9	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9874	9874	T	A	MI.8063	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	668	223	L	Q	cTa/cAa	-2,88	0	0	probably_damaging	1	neutral	0,29	neutral	2,15	deleterious	-3,02	deleterious	-3,1	medium_impact	2,33	neutral	0,74	damaging	0,2	deleterious	4,32	24	0,09	0,35	neutral	0,45	disease	0,54	neutral	0,3	neutral	0,48	0	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,72	low_impact	-3,78	medium_impact	-0,03	medium_impact	0,91	0,15	0,8	20,69	26,81	N	0,34	N	0,92	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9874	9874	T	G	MI.8064	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	668	223	L	R	cTa/cGa	-2,88	0	0	probably_damaging	1	neutral	0,35	neutral	2,17	neutral	-1,63	deleterious	-3,43	low_impact	1,45	neutral	0,61	damaging	0,06	deleterious	4,33	24	0,06	0,35	neutral	0,34	disease	0,72	neutral	0,43	disease	0,55	1	deleterious	1	neutral	0,18	neutral	-2	deleterious	0,75	low_impact	-3,78	medium_impact	0,04	medium_impact	0,12	0,13	0,8	20,69	26,81	N	0,24	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9876	9876	A	G	MI.8065	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	670	224	M	V	Ata/Gta	-3,34	0	0	benign	0	neutral	0,5	neutral	2,34	neutral	0,96	neutral	-1,26	low_impact	0,87	neutral	0,78	neutral	0,72	neutral	-0,75	0,06	0,32	0,5	neutral	0,13	neutral	0,4	neutral	0,34	neutral	0,43	1	neutral	0,49	deleterious	0,75	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	0,19	medium_impact	-0,4	0,26	0,8	24,52	40,54	N	0,31	N	0,15	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9876	9876	A	C	MI.8066	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	670	224	M	L	Ata/Cta	-3,34	0	0	benign	0	neutral	0,66	neutral	2,35	neutral	1,17	neutral	-0,62	neutral_impact	-0,8	neutral	0,78	neutral	0,9	neutral	-0,78	0,05	0,27	0,45	neutral	0,11	neutral	0,27	neutral	0,19	neutral	0,41	2	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	0,36	low_impact	-1,9	0,24	0,8	24,52	40,54	N	0,38	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9876	9876	A	T	MI.8067	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	670	224	M	L	Ata/Tta	-3,34	0	0	benign	0	neutral	0,66	neutral	2,35	neutral	1,17	neutral	-0,62	neutral_impact	-0,8	neutral	0,78	neutral	0,9	neutral	-0,67	0,08	0,27	0,45	neutral	0,11	neutral	0,27	neutral	0,19	neutral	0,41	2	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	0,36	low_impact	-1,9	0,24	0,8	24,52	40,54	N	0,38	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9877	9877	T	C	MI.8068	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	671	224	M	T	aTa/aCa	-0,1	0	0,01	benign	0,01	neutral	0,39	neutral	2,38	neutral	1,48	neutral	-1,05	neutral_impact	0,69	neutral	0,76	neutral	0,77	neutral	-0,42	0,34	0,22	0,45	neutral	0,11	neutral	0,37	neutral	0,38	neutral	0,43	1	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,11	medium_impact	1,07	medium_impact	0,08	medium_impact	-0,56	0,04	0,8	24,52	40,54	N	0,36	N	0,15	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9877	9877	T	A	MI.8069	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	671	224	M	K	aTa/aAa	-0,1	0	0,01	benign	0,01	neutral	0,3	neutral	2,44	neutral	2,62	neutral	-0,62	neutral_impact	-0,98	neutral	0,79	neutral	0,88	deleterious	0,44	6,92	0,13	0,4	neutral	0,2	neutral	0,36	neutral	0,31	neutral	0,44	1	neutral	0,69	deleterious	0,65	neutral	-6	neutral	0,13	medium_impact	1,07	medium_impact	-0,02	low_impact	-2,06	0,12	0,8	24,52	40,54	N	0,33	N	0,23	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8906	8906	A	G	MI.807	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	380	127	H	R	cAc/cGc	7,3	1	0	probably_damaging	0,99	deleterious	0,01	neutral	3,77	neutral	-1,97	deleterious	-7,39	high_impact	4,06	damaging	0,49	neutral	0,34	deleterious	3,07	22,4	0,59	0,7	disease	0,61	disease	0,84	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,65	medium_impact	-0,84	high_impact	2,38	0,35	0,9	50,44	8,73	P	0,55	P	1	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9878	9878	A	C	MI.8070	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	672	224	M	I	atA/atC	0,13	0	0	benign	0	neutral	0,4	neutral	2,32	neutral	-0,15	neutral	-1,22	neutral_impact	0,66	neutral	0,78	neutral	0,56	deleterious	-0,05	2,15	0,25	0,45	neutral	0,21	neutral	0,44	neutral	0,32	neutral	0,47	1	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,13	high_impact	2,05	medium_impact	0,09	medium_impact	-0,59	0,34	0,8	24,52	40,54	N	0,34	N	0,06	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9878	9878	A	T	MI.8071	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	672	224	M	I	atA/atT	0,13	0	0	benign	0	neutral	0,4	neutral	2,32	neutral	-0,15	neutral	-1,22	neutral_impact	0,66	neutral	0,78	neutral	0,56	deleterious	0,02	2,73	0,25	0,45	neutral	0,21	neutral	0,44	neutral	0,32	neutral	0,47	1	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,13	high_impact	2,05	medium_impact	0,09	medium_impact	-0,59	0,34	0,8	24,52	40,54	N	0,35	N	0,06	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9879	9879	T	C	MI.8072	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	673	225	F	L	Ttt/Ctt	-1,72	0	0	benign	0,14	neutral	0,59	neutral	2,61	neutral	0,3	deleterious	-2,56	low_impact	1,42	neutral	0,74	neutral	0,69	neutral	1,4	12,8	0,19	0,45	neutral	0,16	neutral	0,4	neutral	0,3	neutral	0,45	1	neutral	0,3	deleterious	0,73	neutral	-6	neutral	0,23	medium_impact	-0,1	medium_impact	0,28	medium_impact	0,09	0,33	0,8	20,31	24,77	N	0,32	N	0,54	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9879	9879	T	G	MI.8073	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	673	225	F	V	Ttt/Gtt	-1,72	0	0	benign	0,37	neutral	0,31	neutral	2,58	neutral	0,27	deleterious	-2,99	medium_impact	2,57	neutral	0,71	neutral	0,52	deleterious	3,74	23,3	0,18	0,45	neutral	0,17	disease	0,62	neutral	0,32	disease	0,5	0	neutral	0,63	deleterious	0,47	neutral	-3	neutral	0,35	medium_impact	-0,64	medium_impact	-0,01	medium_impact	1,12	0,25	0,8	20,31	24,77	N	0,43	N	0,76	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9879	9879	T	A	MI.8074	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	673	225	F	I	Ttt/Att	-1,72	0	0	benign	0,21	neutral	0,3	neutral	2,57	neutral	0,06	deleterious	-2,65	medium_impact	2,37	neutral	0,73	neutral	0,59	deleterious	4,06	23,7	0,18	0,45	neutral	0,21	disease	0,55	neutral	0,32	disease	0,5	0	neutral	0,64	deleterious	0,55	neutral	-3	neutral	0,36	medium_impact	-0,31	medium_impact	-0,02	medium_impact	0,94	0,27	0,8	20,31	24,77	N	0,44	N	0,54	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9880	9880	T	G	MI.8075	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	674	225	F	C	tTt/tGt	3,14	0,16	0	probably_damaging	0,93	neutral	0,11	neutral	2,51	neutral	-2,39	deleterious	-2,9	medium_impact	1,94	neutral	0,73	neutral	0,57	deleterious	3,17	22,7	0,07	0,35	neutral	0,49	disease	0,67	neutral	0,23	neutral	0,46	1	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,69	low_impact	-1,96	medium_impact	-0,33	medium_impact	0,56	0,19	0,8	20,31	24,77	N	0,38	N	0,81	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9880	9880	T	A	MI.8076	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	674	225	F	Y	tTt/tAt	3,14	0,16	0	benign	0	neutral	0,95	neutral	2,59	neutral	0,43	neutral	0,09	neutral_impact	0,18	neutral	0,8	neutral	0,96	neutral	-0,07	1,99	0,25	0,45	neutral	0,11	neutral	0,26	neutral	0,15	neutral	0,42	2	neutral	0,03	deleterious	0,98	neutral	-6	neutral	0,12	high_impact	2,05	medium_impact	0,92	low_impact	-1,02	0,28	0,8	20,31	24,77	N	0,37	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9880	9880	T	C	MI.8077	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	674	225	F	S	tTt/tCt	3,14	0,16	0	possibly_damaging	0,46	neutral	0,44	neutral	2,56	neutral	1,26	neutral	-2,23	low_impact	0,96	neutral	0,76	neutral	0,78	deleterious	3,1	22,5	0,1	0,4	neutral	0,16	neutral	0,46	neutral	0,29	neutral	0,45	1	neutral	0,52	deleterious	0,49	neutral	-3	deleterious	0,47	medium_impact	-0,8	medium_impact	0,13	medium_impact	-0,32	0,19	0,8	20,31	24,77	N	0,35	N	0,87	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9881	9881	T	A	MI.8078	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	675	225	F	L	ttT/ttA	-0,1	0	0	benign	0,14	neutral	0,59	neutral	2,61	neutral	0,3	deleterious	-2,56	low_impact	1,42	neutral	0,74	neutral	0,69	deleterious	1,84	15,22	0,19	0,45	neutral	0,16	neutral	0,4	neutral	0,3	neutral	0,45	1	neutral	0,3	deleterious	0,73	neutral	-6	neutral	0,23	medium_impact	-0,1	medium_impact	0,28	medium_impact	0,09	0,33	0,8	20,31	24,77	N	0,31	N	0,54	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9881	9881	T	G	MI.8079	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	675	225	F	L	ttT/ttG	-0,1	0	0	benign	0,14	neutral	0,59	neutral	2,61	neutral	0,3	deleterious	-2,56	low_impact	1,42	neutral	0,74	neutral	0,69	neutral	1,77	14,83	0,19	0,45	neutral	0,16	neutral	0,4	neutral	0,3	neutral	0,45	1	neutral	0,3	deleterious	0,73	neutral	-6	neutral	0,23	medium_impact	-0,1	medium_impact	0,28	medium_impact	0,09	0,33	0,8	20,31	24,77	N	0,31	N	0,54	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8906	8906	A	T	MI.808	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	380	127	H	L	cAc/cTc	7,3	1	0	probably_damaging	0,99	deleterious	0,02	neutral	3,95	neutral	0,33	deleterious	-10,17	medium_impact	2,27	neutral	0,62	neutral	0,39	deleterious	3,91	23,5	0,35	0,65	disease	0,51	disease	0,84	disease	0,75	disease	0,62	2	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,79	low_impact	-2,65	medium_impact	-0,66	medium_impact	0,85	0,31	0,9	50,44	8,73	N	0,48	N	0,96	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9882	9882	C	A	MI.8080	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	676	226	H	N	Cac/Aac	-3,57	0	0	probably_damaging	0,99	neutral	0,47	neutral	2,11	neutral	-2,02	deleterious	-6,13	medium_impact	2,54	neutral	0,61	damaging	0,25	deleterious	4,04	23,7	0,53	0,6	neutral	0,21	disease	0,78	disease	0,68	disease	0,65	3	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,74	low_impact	-2,81	medium_impact	0,16	medium_impact	1,09	0,22	0,8	74,33	11,46	N	0,24	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9882	9882	C	G	MI.8081	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	676	226	H	D	Cac/Gac	-3,57	0	0	probably_damaging	1	neutral	0,18	neutral	2,13	neutral	-1,68	deleterious	-7,92	medium_impact	2,88	neutral	0,64	damaging	0,26	deleterious	4,03	23,7	0,1	0,4	neutral	0,24	disease	0,78	disease	0,71	disease	0,55	1	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,75	low_impact	-3,78	medium_impact	-0,18	medium_impact	1,4	0,24	0,8	74,33	11,46	N	0,31	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9882	9882	C	T	MI.8082	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	676	226	H	Y	Cac/Tac	-3,57	0	0	probably_damaging	0,99	neutral	0,64	neutral	2,06	deleterious	-3,74	deleterious	-5,35	high_impact	3,88	neutral	0,6	damaging	0,16	deleterious	3,86	23,5	0,39	0,5	neutral	0,48	disease	0,87	disease	0,66	disease	0,73	5	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,82	low_impact	-2,81	medium_impact	0,33	high_impact	2,3	0,19	0,8	74,33	11,46	N	0,25	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9883	9883	A	C	MI.8083	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	677	226	H	P	cAc/cCc	5,45	1	0	probably_damaging	1	neutral	0,12	neutral	2,06	deleterious	-3,47	deleterious	-8,86	high_impact	4,08	damaging	0,56	damaging	0,25	deleterious	3,38	22,9	0,05	0,35	neutral	0,41	disease	0,88	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,3	high_impact	2,47	0,16	0,8	74,33	11,46	P	0,51	P	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9883	9883	A	T	MI.8084	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	677	226	H	L	cAc/cTc	5,45	1	0	probably_damaging	0,99	neutral	0,54	neutral	2,08	neutral	-2,66	deleterious	-9,76	medium_impact	3,4	neutral	0,63	neutral	0,33	deleterious	3,97	23,6	0,11	0,4	neutral	0,31	disease	0,86	disease	0,69	disease	0,68	4	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,78	low_impact	-2,81	medium_impact	0,23	medium_impact	1,86	0,16	0,8	74,33	11,46	N	0,47	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9883	9883	A	G	MI.8085	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	677	226	H	R	cAc/cGc	5,45	1	0	probably_damaging	0,99	neutral	0,21	neutral	2,13	neutral	-1,65	deleterious	-7	medium_impact	2,7	neutral	0,64	damaging	0,21	deleterious	3,17	22,7	0,25	0,45	neutral	0,2	disease	0,86	disease	0,67	disease	0,73	5	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,78	low_impact	-2,81	medium_impact	-0,14	medium_impact	1,24	0,17	0,8	74,33	11,46	N	0,39	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9884	9884	C	G	MI.8086	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	678	226	H	Q	caC/caG	5,68	1	0	probably_damaging	1	neutral	0,24	neutral	2,16	neutral	-1,29	deleterious	-6,82	medium_impact	1,97	damaging	0,49	neutral	0,66	deleterious	3,7	23,3	0,35	0,5	neutral	0,21	disease	0,61	disease	0,53	neutral	0,42	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,72	low_impact	-3,78	medium_impact	-0,09	medium_impact	0,58	0,23	0,8	74,33	11,46	N	0,5	N	0,94	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9884	9884	C	A	MI.8087	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	678	226	H	Q	caC/caA	5,68	1	0	probably_damaging	1	neutral	0,24	neutral	2,16	neutral	-1,29	deleterious	-6,82	medium_impact	1,97	damaging	0,49	neutral	0,66	deleterious	3,98	23,6	0,35	0,5	neutral	0,21	disease	0,61	disease	0,53	neutral	0,42	2	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,72	low_impact	-3,78	medium_impact	-0,09	medium_impact	0,58	0,23	0,8	74,33	11,46	N	0,5	N	0,94	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9885	9885	T	G	MI.8088	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	679	227	F	V	Ttt/Gtt	-0,1	0,87	0	probably_damaging	1	neutral	0,49	neutral	2,16	neutral	-1,22	deleterious	-5,99	medium_impact	3,27	neutral	0,63	damaging	0,03	deleterious	4,31	24	0,11	0,4	neutral	0,14	disease	0,85	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,74	low_impact	-3,78	medium_impact	0,18	medium_impact	1,75	0,28	0,8	74,71	11,66	N	0,26	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9885	9885	T	C	MI.8089	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	679	227	F	L	Ttt/Ctt	-0,1	0,87	0	probably_damaging	0,98	neutral	0,73	neutral	2,44	neutral	0,54	deleterious	-5,05	medium_impact	2,04	damaging	0,5	damaging	0,06	deleterious	4,36	24,1	0,21	0,45	neutral	0,12	disease	0,64	neutral	0,42	neutral	0,43	1	deleterious	0,98	neutral	0,38	deleterious	1	deleterious	0,71	low_impact	-2,51	medium_impact	0,44	medium_impact	0,65	0,54	0,8	74,71	11,66	N	0,26	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8906	8906	A	C	MI.809	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	380	127	H	P	cAc/cCc	7,3	1	0	probably_damaging	0,99	deleterious	0	neutral	3,76	neutral	-2,63	deleterious	-9,27	high_impact	4,41	damaging	0,52	neutral	0,38	deleterious	3,3	22,9	0,29	0,65	disease	0,63	disease	0,88	disease	0,85	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,85	low_impact	-2,65	low_impact	-1,4	high_impact	2,68	0,4	0,9	50,44	8,73	P	0,61	P	1	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9885	9885	T	A	MI.8090	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	679	227	F	I	Ttt/Att	-0,1	0,87	0	probably_damaging	0,99	neutral	0,41	neutral	2,16	neutral	-1,2	deleterious	-5,13	medium_impact	3,08	neutral	0,63	damaging	0,04	deleterious	4,84	24,8	0,15	0,45	neutral	0,19	disease	0,84	disease	0,6	disease	0,68	4	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,75	low_impact	-2,81	medium_impact	0,1	medium_impact	1,58	0,44	0,8	74,71	11,66	N	0,28	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9886	9886	T	C	MI.8091	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	680	227	F	S	tTt/tCt	7,53	1	0	probably_damaging	1	neutral	0,52	neutral	2,06	neutral	-2,9	deleterious	-6,96	medium_impact	3,02	neutral	0,69	damaging	0,02	deleterious	4,37	24,1	0,03	0,35	neutral	0,27	disease	0,81	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,78	low_impact	-3,78	medium_impact	0,21	medium_impact	1,52	0,16	0,8	74,71	11,66	N	0,41	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9886	9886	T	G	MI.8092	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	680	227	F	C	tTt/tGt	7,53	1	0	probably_damaging	1	neutral	0,2	neutral	2,04	deleterious	-4,36	deleterious	-6,95	high_impact	3,92	neutral	0,7	damaging	0,02	deleterious	4,23	23,9	0,05	0,35	neutral	0,48	disease	0,87	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,15	high_impact	2,33	0,15	0,8	74,71	11,66	N	0,48	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9886	9886	T	A	MI.8093	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	680	227	F	Y	tTt/tAt	7,53	1	0	probably_damaging	0,98	neutral	1	neutral	2,07	neutral	-2,59	neutral	-2,25	low_impact	1,9	damaging	0,57	damaging	0,1	deleterious	4,33	24	0,16	0,45	neutral	0,29	disease	0,79	neutral	0,42	disease	0,53	1	deleterious	0,98	deleterious	0,51	neutral	-2	deleterious	0,77	low_impact	-2,51	high_impact	1,9	medium_impact	0,52	0,49	0,8	74,71	11,66	N	0,43	N	0,8	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9887	9887	T	G	MI.8094	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	681	227	F	L	ttT/ttG	5,68	1	0	probably_damaging	0,98	neutral	0,73	neutral	2,44	neutral	0,54	deleterious	-5,05	medium_impact	2,04	damaging	0,5	damaging	0,06	deleterious	4,45	24,2	0,21	0,45	neutral	0,12	disease	0,64	neutral	0,42	neutral	0,43	1	deleterious	0,98	neutral	0,38	deleterious	1	deleterious	0,71	low_impact	-2,51	medium_impact	0,44	medium_impact	0,65	0,54	0,8	74,71	11,66	N	0,43	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9887	9887	T	A	MI.8095	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	681	227	F	L	ttT/ttA	5,68	1	0	probably_damaging	0,98	neutral	0,73	neutral	2,44	neutral	0,54	deleterious	-5,05	medium_impact	2,04	damaging	0,5	damaging	0,06	deleterious	4,58	24,4	0,21	0,45	neutral	0,12	disease	0,64	neutral	0,42	neutral	0,43	1	deleterious	0,98	neutral	0,38	deleterious	1	deleterious	0,71	low_impact	-2,51	medium_impact	0,44	medium_impact	0,65	0,54	0,8	74,71	11,66	N	0,43	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9888	9888	A	C	MI.8096	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	682	228	T	P	Aca/Cca	-7,28	0	0	probably_damaging	1	neutral	0,21	neutral	2,03	deleterious	-3,65	deleterious	-3,39	medium_impact	3,38	damaging	0,48	damaging	0,05	deleterious	3,66	23,2	0,07	0,35	disease	0,59	disease	0,83	disease	0,61	disease	0,73	5	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,81	low_impact	-3,78	medium_impact	-0,14	medium_impact	1,85	0,29	0,8	73,18	12,16	N	0,27	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9888	9888	A	T	MI.8097	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	682	228	T	S	Aca/Tca	-7,28	0	0	probably_damaging	0,98	neutral	0,44	neutral	2,24	neutral	-1,25	neutral	0,07	neutral_impact	0,02	damaging	0,56	damaging	0,1	neutral	1,67	14,23	0,57	0,65	neutral	0,3	neutral	0,07	neutral	0,19	neutral	0,25	5	neutral	0,97	neutral	0,23	neutral	-2	deleterious	0,65	low_impact	-2,51	medium_impact	0,13	low_impact	-1,17	0,58	0,8	73,18	12,16	N	0,42	N	0,77	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9888	9888	A	G	MI.8098	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	682	228	T	A	Aca/Gca	-7,28	0	0	probably_damaging	0,98	neutral	0,54	neutral	2,13	neutral	-2,17	neutral	-1,92	medium_impact	3,13	damaging	0,51	damaging	0,04	deleterious	3,63	23,2	0,35	0,5	neutral	0,31	disease	0,52	disease	0,63	disease	0,68	4	neutral	0,97	neutral	0,28	deleterious	1	deleterious	0,68	low_impact	-2,51	medium_impact	0,23	medium_impact	1,62	0,28	0,8	73,18	12,16	N	0,26	N	0,44	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9889	9889	C	A	MI.8099	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	683	228	T	K	aCa/aAa	8,69	1	0	probably_damaging	1	neutral	0,33	neutral	2,08	neutral	-1,66	deleterious	-2,85	medium_impact	2,73	damaging	0,51	damaging	0,02	deleterious	4,58	24,4	0,11	0,4	neutral	0,33	disease	0,83	disease	0,6	disease	0,73	5	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,75	low_impact	-3,78	medium_impact	0,02	medium_impact	1,26	0,33	0,8	73,18	12,16	N	0,45	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8561	8561	C	T	MI.81	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	35	12	P	L	cCc/cTc	7,3	1	0	probably_damaging	1	deleterious	0,04	neutral	4,63	neutral	0,66	deleterious	-8,73	medium_impact	2,67	damaging	0,58	damaging	0,05	deleterious	4,18	23,8	0,37	0,65	neutral	0,27	disease	0,89	disease	0,71	disease	0,79	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,74	low_impact	-3,6	medium_impact	-0,49	medium_impact	1,19	0,8	0,9	50	8,94	N	0,43	N	0,97	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8907	8907	C	G	MI.810	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	381	127	H	Q	caC/caG	6,84	1	0	probably_damaging	0,99	deleterious	0,01	neutral	3,76	neutral	-2,32	deleterious	-7,39	medium_impact	3,25	neutral	0,61	neutral	0,38	deleterious	3,63	23,2	0,56	0,65	disease	0,69	disease	0,83	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,81	low_impact	-2,65	medium_impact	-0,84	medium_impact	1,69	0,56	0,9	50,44	8,73	N	0,49	N	0,95	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9889	9889	C	T	MI.8100	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	683	228	T	M	aCa/aTa	8,69	1	0	probably_damaging	1	neutral	0,22	neutral	2,02	deleterious	-4,12	deleterious	-3,36	medium_impact	3,38	damaging	0,51	damaging	0,01	deleterious	4,13	23,8	0,11	0,4	disease	0,56	disease	0,65	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	-0,12	medium_impact	1,85	0,41	0,8	73,18	12,16	P	0,5	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9891	9891	T	A	MI.8101	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	685	229	S	T	Tcc/Acc	-0,1	0,28	0	benign	0,08	neutral	0,71	neutral	2,29	neutral	-1	neutral	-0,1	neutral_impact	0,69	neutral	0,73	neutral	0,78	deleterious	0,63	8,36	0,57	0,65	neutral	0,23	neutral	0,34	neutral	0,18	neutral	0,45	1	neutral	0,19	deleterious	0,82	neutral	-6	neutral	0,17	medium_impact	0,16	medium_impact	0,41	medium_impact	-0,56	0,42	0,8	36,78	13,35	N	0,36	N	0,63	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9891	9891	T	C	MI.8102	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	685	229	S	P	Tcc/Ccc	-0,1	0,28	0	benign	0,01	neutral	0,34	neutral	2,21	neutral	0,02	neutral	-2,12	neutral_impact	0,73	neutral	0,78	neutral	0,73	neutral	1,02	10,77	0,17	0,45	neutral	0,23	disease	0,68	neutral	0,19	neutral	0,44	1	neutral	0,65	deleterious	0,67	neutral	-6	neutral	0,19	medium_impact	1,07	medium_impact	0,03	medium_impact	-0,53	0,15	0,8	36,78	13,35	N	0,41	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9891	9891	T	G	MI.8103	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	685	229	S	A	Tcc/Gcc	-0,1	0,28	0	benign	0,08	neutral	0,91	neutral	2,29	neutral	0,25	neutral	-1,55	low_impact	1,5	neutral	0,74	neutral	0,8	neutral	1,17	11,56	0,62	0,65	neutral	0,17	neutral	0,36	neutral	0,31	neutral	0,45	1	neutral	0,03	deleterious	0,92	neutral	-6	neutral	0,15	medium_impact	0,16	medium_impact	0,76	medium_impact	0,16	0,25	0,8	36,78	13,35	N	0,3	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9892	9892	C	T	MI.8104	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	686	229	S	F	tCc/tTc	0,36	0,33	0	possibly_damaging	0,89	neutral	0,44	neutral	2,2	deleterious	-3,42	deleterious	-3,73	low_impact	1,83	neutral	0,62	neutral	0,48	deleterious	4,33	24	0,13	0,4	disease	0,54	disease	0,79	neutral	0,49	disease	0,62	2	neutral	0,89	neutral	0,28	neutral	-3	deleterious	0,74	low_impact	-1,75	medium_impact	0,13	medium_impact	0,46	0,03	0,8	36,78	13,35	N	0,26	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9892	9892	C	A	MI.8105	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	686	229	S	Y	tCc/tAc	0,36	0,33	0	possibly_damaging	0,89	neutral	0,53	neutral	2,22	deleterious	-3,21	deleterious	-3,46	medium_impact	2,29	neutral	0,65	neutral	0,33	deleterious	4,32	24	0,14	0,4	neutral	0,38	disease	0,82	neutral	0,5	disease	0,66	3	neutral	0,88	neutral	0,32	NA	0	deleterious	0,71	low_impact	-1,75	medium_impact	0,22	medium_impact	0,87	0,15	0,8	36,78	13,35	N	0,23	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9892	9892	C	G	MI.8106	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	686	229	S	C	tCc/tGc	0,36	0,33	0	possibly_damaging	0,82	neutral	0,13	neutral	2,18	deleterious	-4,66	deleterious	-3,04	medium_impact	3,19	neutral	0,64	neutral	0,39	deleterious	3,68	23,3	0,14	0,4	disease	0,68	disease	0,76	neutral	0,37	disease	0,59	2	neutral	0,93	neutral	0,16	NA	0	deleterious	0,7	low_impact	-1,51	medium_impact	-0,28	medium_impact	1,68	0,19	0,8	36,78	13,35	N	0,36	N	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9894	9894	A	G	MI.8107	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	688	230	K	E	Aaa/Gaa	-20	0	0	benign	0,05	neutral	1	neutral	2,34	neutral	0,31	neutral	-0,16	neutral_impact	0,08	neutral	0,72	neutral	0,45	deleterious	0,1	3,66	0,22	0,45	neutral	0,12	neutral	0,38	neutral	0,43	neutral	0,43	1	neutral	0,05	deleterious	0,98	neutral	-6	neutral	0,12	medium_impact	0,37	high_impact	1,9	low_impact	-1,11	0,51	0,8	NA	NA	N	0,27	N	0,56	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9894	9894	A	C	MI.8108	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	688	230	K	Q	Aaa/Caa	-20	0	0	benign	0,14	neutral	0,61	neutral	2,31	neutral	-0,84	neutral	-0,27	neutral_impact	0,25	neutral	0,73	neutral	0,48	deleterious	0,12	3,84	0,38	0,5	neutral	0,17	neutral	0,29	neutral	0,24	neutral	0,43	1	neutral	0,28	deleterious	0,74	neutral	-6	neutral	0,14	medium_impact	-0,1	medium_impact	0,3	medium_impact	-0,96	0,36	0,8	NA	NA	N	0,36	N	0,62	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9895	9895	A	T	MI.8109	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	689	230	K	M	aAa/aTa	1,98	0	0	possibly_damaging	0,56	neutral	0,26	neutral	2,22	deleterious	-3,15	neutral	-1,23	low_impact	1,85	neutral	0,77	neutral	0,35	deleterious	3,83	23,4	0,13	0,4	neutral	0,44	neutral	0,3	neutral	0,41	neutral	0,46	1	neutral	0,74	neutral	0,35	neutral	-3	deleterious	0,45	medium_impact	-0,97	medium_impact	-0,07	medium_impact	0,48	0,28	0,8	NA	NA	N	0,41	N	0,72	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8907	8907	C	A	MI.811	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	381	127	H	Q	caC/caA	6,84	1	0	probably_damaging	0,99	deleterious	0,01	neutral	3,76	neutral	-2,32	deleterious	-7,39	medium_impact	3,25	neutral	0,61	neutral	0,38	deleterious	3,9	23,5	0,56	0,65	disease	0,69	disease	0,83	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,81	low_impact	-2,65	medium_impact	-0,84	medium_impact	1,69	0,56	0,9	50,44	8,73	P	0,49	N	0,95	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9895	9895	A	C	MI.8110	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	689	230	K	T	aAa/aCa	1,98	0	0	benign	0,05	neutral	0,69	neutral	2,29	neutral	-1,14	neutral	0,63	neutral_impact	0,16	neutral	0,78	neutral	0,87	neutral	-0,22	1	0,15	0,45	neutral	0,19	neutral	0,21	neutral	0,24	neutral	0,35	3	neutral	0,24	deleterious	0,82	neutral	-6	neutral	0,12	medium_impact	0,37	medium_impact	0,39	low_impact	-1,04	0,25	0,8	NA	NA	N	0,29	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9896	9896	A	T	MI.8111	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	690	230	K	N	aaA/aaT	0,36	0	0	benign	0	neutral	0,61	neutral	2,32	neutral	-0,94	neutral	1,46	neutral_impact	-0,22	neutral	0,77	neutral	0,96	neutral	-0,6	0,13	0,47	0,55	neutral	0,12	neutral	0,19	neutral	0,21	neutral	0,35	3	neutral	0,39	deleterious	0,81	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	0,3	low_impact	-1,38	0,33	0,8	NA	NA	N	0,33	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9896	9896	A	C	MI.8112	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	690	230	K	N	aaA/aaC	0,36	0	0	benign	0	neutral	0,61	neutral	2,32	neutral	-0,94	neutral	1,46	neutral_impact	-0,22	neutral	0,77	neutral	0,96	neutral	-0,64	0,1	0,47	0,55	neutral	0,12	neutral	0,19	neutral	0,21	neutral	0,35	3	neutral	0,39	deleterious	0,81	neutral	-6	neutral	0,1	high_impact	2,05	medium_impact	0,3	low_impact	-1,38	0,33	0,8	NA	NA	N	0,32	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9897	9897	C	G	MI.8113	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	691	231	H	D	Cat/Gat	-6,81	0	0	probably_damaging	0,99	neutral	0,2	neutral	1,94	deleterious	-3,1	deleterious	-8,22	medium_impact	2,73	damaging	0,58	damaging	0,02	deleterious	4,04	23,7	0,06	0,35	neutral	0,24	disease	0,85	disease	0,78	disease	0,76	5	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,77	low_impact	-2,81	medium_impact	-0,15	medium_impact	1,26	0,51	0,8	73,95	12,04	N	0,31	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9897	9897	C	T	MI.8114	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	691	231	H	Y	Cat/Tat	-6,81	0	0	probably_damaging	0,98	neutral	1	neutral	1,91	deleterious	-3,8	deleterious	-5,48	high_impact	3,62	damaging	0,58	damaging	0,02	deleterious	3,86	23,5	0,24	0,45	neutral	0,32	disease	0,88	disease	0,78	disease	0,78	6	deleterious	0,98	deleterious	0,51	deleterious	2	deleterious	0,81	low_impact	-2,51	high_impact	1,9	high_impact	2,06	0,32	0,8	73,95	12,04	N	0,28	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9897	9897	C	A	MI.8115	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	691	231	H	N	Cat/Aat	-6,81	0	0	probably_damaging	0,99	neutral	0,4	neutral	1,94	deleterious	-3,14	deleterious	-6,38	medium_impact	2,03	damaging	0,56	damaging	0,02	deleterious	4,27	23,9	0,37	0,5	neutral	0,21	disease	0,82	disease	0,73	disease	0,63	3	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,76	low_impact	-2,81	medium_impact	0,09	medium_impact	0,64	0,37	0,8	73,95	12,04	N	0,2	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9898	9898	A	C	MI.8116	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	692	231	H	P	cAt/cCt	5,45	1	0	probably_damaging	1	neutral	0,23	neutral	1,9	deleterious	-4,35	deleterious	-9,13	high_impact	3,96	damaging	0,56	damaging	0,02	deleterious	3,28	22,8	0,04	0,35	neutral	0,4	disease	0,89	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,11	high_impact	2,37	0,16	0,8	73,95	12,04	N	0,5	N	0,98	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9898	9898	A	T	MI.8117	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	692	231	H	L	cAt/cTt	5,45	1	0	probably_damaging	0,98	neutral	0,67	neutral	1,93	deleterious	-3,21	deleterious	-10,04	high_impact	3,96	damaging	0,56	damaging	0,02	deleterious	3,84	23,4	0,09	0,35	neutral	0,21	disease	0,88	disease	0,77	disease	0,77	5	deleterious	0,98	neutral	0,35	deleterious	2	deleterious	0,78	low_impact	-2,51	medium_impact	0,37	high_impact	2,37	0,13	0,8	73,95	12,04	N	0,49	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9898	9898	A	G	MI.8118	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	692	231	H	R	cAt/cGt	5,45	1	0	probably_damaging	0,98	neutral	0,35	neutral	2,02	neutral	-1,75	deleterious	-7,31	medium_impact	2,34	neutral	0,63	damaging	0,03	deleterious	3,08	22,5	0,19	0,45	neutral	0,19	disease	0,84	disease	0,71	disease	0,54	1	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,79	low_impact	-2,51	medium_impact	0,04	medium_impact	0,92	0,15	0,8	73,95	12,04	N	0,32	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9899	9899	T	A	MI.8119	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	693	231	H	Q	caT/caA	8,69	1	0,02	probably_damaging	0,99	neutral	0,31	neutral	1,95	neutral	-2,81	deleterious	-7,31	medium_impact	2,09	damaging	0,5	damaging	0,05	deleterious	3,87	23,5	0,26	0,45	neutral	0,18	disease	0,73	disease	0,73	disease	0,59	2	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,74	low_impact	-2,81	medium_impact	-0,01	medium_impact	0,69	0,39	0,8	73,95	12,04	N	0,42	N	0,94	polymorphism	1	0,1	rs41345446	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8908	8908	T	A	MI.812	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	382	128	F	I	Ttc/Atc	-1,95	0	0	benign	0,02	neutral	0,08	neutral	4,34	neutral	-2,18	neutral	-1,03	medium_impact	2,21	neutral	0,86	neutral	0,59	deleterious	2,66	20,6	0,26	0,65	disease	0,64	neutral	0,46	disease	0,56	disease	0,64	3	neutral	0,92	deleterious	0,53	neutral	-3	neutral	0,23	medium_impact	0,85	medium_impact	-0,31	medium_impact	0,8	0,51	0,9	19,91	15,56	N	0,42	N	0,75	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9899	9899	T	G	MI.8120	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	693	231	H	Q	caT/caG	8,69	1	0,02	probably_damaging	0,99	neutral	0,31	neutral	1,95	neutral	-2,81	deleterious	-7,31	medium_impact	2,09	damaging	0,5	damaging	0,05	deleterious	3,74	23,3	0,26	0,45	neutral	0,18	disease	0,73	disease	0,73	disease	0,59	2	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,74	low_impact	-2,81	medium_impact	-0,01	medium_impact	0,69	0,39	0,8	73,95	12,04	N	0,4	N	0,94	polymorphism	1	0,1	rs41345446	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9900	9900	C	G	MI.8121	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	694	232	H	D	Cac/Gac	-2,88	0	0	probably_damaging	1	neutral	0,16	neutral	2	neutral	-2,4	deleterious	-8,18	high_impact	3,69	neutral	0,61	damaging	0,02	deleterious	3,98	23,6	0,06	0,35	neutral	0,29	disease	0,88	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,22	high_impact	2,12	0,16	0,8	73,56	11,8	N	0,39	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9900	9900	C	A	MI.8122	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	694	232	H	N	Cac/Aac	-2,88	0	0	probably_damaging	0,99	neutral	0,37	neutral	2,03	neutral	-1,98	deleterious	-6,37	high_impact	3,52	damaging	0,59	damaging	0,02	deleterious	4,15	23,8	0,23	0,45	neutral	0,28	disease	0,87	disease	0,77	disease	0,73	5	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,78	low_impact	-2,81	medium_impact	0,06	medium_impact	1,97	0,14	0,8	73,56	11,8	N	0,33	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9900	9900	C	T	MI.8123	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	694	232	H	Y	Cac/Tac	-2,88	0	0	probably_damaging	0,99	neutral	0,82	neutral	1,95	deleterious	-3,58	deleterious	-5,47	medium_impact	2,17	damaging	0,51	damaging	0,04	deleterious	3,84	23,4	0,18	0,45	neutral	0,19	disease	0,9	disease	0,73	disease	0,72	4	deleterious	0,99	neutral	0,42	deleterious	1	deleterious	0,79	low_impact	-2,81	medium_impact	0,57	medium_impact	0,76	0,1	0,8	73,56	11,8	N	0,25	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9901	9901	A	T	MI.8124	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	695	232	H	L	cAc/cTc	5,45	1	0	probably_damaging	1	neutral	0,6	neutral	1,96	deleterious	-3,22	deleterious	-9,99	medium_impact	3,46	damaging	0,58	damaging	0,02	deleterious	3,99	23,6	0,06	0,35	neutral	0,26	disease	0,92	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,82	low_impact	-3,78	medium_impact	0,29	medium_impact	1,92	0,1	0,8	73,56	11,8	N	0,45	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9901	9901	A	G	MI.8125	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	695	232	H	R	cAc/cGc	5,45	1	0	probably_damaging	1	neutral	0,32	neutral	1,99	neutral	-2,53	deleterious	-7,28	high_impact	3,95	neutral	0,7	damaging	0,02	deleterious	3,18	22,7	0,09	0,35	neutral	0,27	disease	0,9	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	0,01	high_impact	2,36	0,17	0,8	73,56	11,8	N	0,48	N	0,99	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9901	9901	A	C	MI.8126	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	695	232	H	P	cAc/cCc	5,45	1	0	probably_damaging	1	neutral	0,16	neutral	1,94	deleterious	-4,12	deleterious	-9,09	high_impact	3,95	damaging	0,57	damaging	0,03	deleterious	3,32	22,9	0,04	0,35	neutral	0,32	disease	0,89	disease	0,74	disease	0,77	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,22	high_impact	2,36	0,06	0,8	73,56	11,8	N	0,47	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9902	9902	C	A	MI.8127	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	696	232	H	Q	caC/caA	8,69	1	0	probably_damaging	1	neutral	0,25	neutral	1,98	neutral	-2,74	deleterious	-7,28	medium_impact	3,46	neutral	0,64	damaging	0,02	deleterious	4,05	23,7	0,14	0,4	neutral	0,25	disease	0,85	disease	0,79	disease	0,77	5	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	-0,08	medium_impact	1,92	0,19	0,8	73,56	11,8	P	0,48	N	0,94	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9902	9902	C	G	MI.8128	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	696	232	H	Q	caC/caG	8,69	1	0	probably_damaging	1	neutral	0,25	neutral	1,98	neutral	-2,74	deleterious	-7,28	medium_impact	3,46	neutral	0,64	damaging	0,02	deleterious	3,77	23,4	0,14	0,4	neutral	0,25	disease	0,85	disease	0,79	disease	0,77	5	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	-0,08	medium_impact	1,92	0,19	0,8	73,56	11,8	P	0,48	N	0,94	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9903	9903	T	G	MI.8129	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	697	233	F	V	Ttt/Gtt	-1,26	0	0	probably_damaging	0,99	neutral	0,21	neutral	2,4	neutral	0,69	deleterious	-5,47	medium_impact	2,17	damaging	0,5	neutral	0,74	deleterious	4,25	23,9	0,1	0,4	neutral	0,12	disease	0,69	neutral	0,37	neutral	0,49	0	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,7	low_impact	-2,81	medium_impact	-0,14	medium_impact	0,76	0,28	0,8	75,1	11,59	N	0,4	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8908	8908	T	C	MI.813	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	382	128	F	L	Ttc/Ctc	-1,95	0	0	benign	0	neutral	1	neutral	4,64	neutral	-0,75	neutral	0,09	neutral_impact	-0,74	neutral	0,93	neutral	0,95	neutral	-0,45	0,29	0,44	0,65	neutral	0,26	neutral	0,12	neutral	0,24	neutral	0,29	4	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,09	high_impact	1,98	low_impact	-1,73	0,73	0,9	19,91	15,56	N	0,34	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9903	9903	T	C	MI.8130	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	697	233	F	L	Ttt/Ctt	-1,26	0	0	probably_damaging	0,98	neutral	0,46	neutral	2,42	neutral	0,84	deleterious	-4,7	low_impact	1,88	damaging	0,48	neutral	0,78	deleterious	4,33	24	0,15	0,45	neutral	0,14	disease	0,62	neutral	0,37	neutral	0,44	1	neutral	0,97	neutral	0,24	neutral	-2	deleterious	0,71	low_impact	-2,51	medium_impact	0,15	medium_impact	0,5	0,5	0,8	75,1	11,59	N	0,47	N	0,92	polymorphism	1	0,08	rs199999390	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9903	9903	T	A	MI.8131	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	697	233	F	I	Ttt/Att	-1,26	0	0	probably_damaging	0,98	neutral	0,33	neutral	2,33	neutral	0,09	deleterious	-4,66	medium_impact	2,84	neutral	0,64	neutral	0,63	deleterious	4,81	24,8	0,14	0,4	neutral	0,15	disease	0,82	disease	0,53	disease	0,51	0	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,75	low_impact	-2,51	medium_impact	0,02	medium_impact	1,36	0,43	0,8	75,1	11,59	N	0,32	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9904	9904	T	C	MI.8132	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	698	233	F	S	tTt/tCt	5,68	1	0	probably_damaging	1	neutral	0,21	neutral	2,25	neutral	-1	deleterious	-6,67	high_impact	4,01	neutral	0,78	neutral	0,58	deleterious	4,38	24,1	0,04	0,35	neutral	0,21	disease	0,81	disease	0,65	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,75	low_impact	-3,78	medium_impact	-0,14	high_impact	2,41	0,16	0,8	75,1	11,59	N	0,51	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	COSM1636304	.	.	.	.	.	.	.	.
chrM	9904	9904	T	A	MI.8133	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	698	233	F	Y	tTt/tAt	5,68	1	0	probably_damaging	0,98	neutral	0,46	neutral	2,24	neutral	-1,31	neutral	-2,5	medium_impact	3,27	neutral	0,68	neutral	0,43	deleterious	4,33	24	0,21	0,45	neutral	0,35	disease	0,83	disease	0,55	disease	0,71	4	neutral	0,97	neutral	0,24	deleterious	1	deleterious	0,77	low_impact	-2,51	medium_impact	0,15	medium_impact	1,75	0,52	0,8	75,1	11,59	P	0,53	P	0,8	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9904	9904	T	G	MI.8134	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	698	233	F	C	tTt/tGt	5,68	1	0	probably_damaging	1	neutral	0,07	neutral	2,21	neutral	-2,57	deleterious	-6,59	high_impact	4,01	neutral	0,69	neutral	0,47	deleterious	4,22	23,9	0,06	0,35	neutral	0,48	disease	0,88	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,45	high_impact	2,41	0,1	0,8	75,1	11,59	P	0,52	P	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9905	9905	T	G	MI.8135	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	699	233	F	L	ttT/ttG	4,76	1	0	probably_damaging	0,98	neutral	0,46	neutral	2,42	neutral	0,84	deleterious	-4,7	low_impact	1,88	damaging	0,48	neutral	0,78	deleterious	4,48	24,2	0,15	0,45	neutral	0,14	disease	0,62	neutral	0,37	neutral	0,44	1	neutral	0,97	neutral	0,24	neutral	-2	deleterious	0,71	low_impact	-2,51	medium_impact	0,15	medium_impact	0,5	0,5	0,8	75,1	11,59	P	0,58	P	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9905	9905	T	A	MI.8136	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	699	233	F	L	ttT/ttA	4,76	1	0	probably_damaging	0,98	neutral	0,46	neutral	2,42	neutral	0,84	deleterious	-4,7	low_impact	1,88	damaging	0,48	neutral	0,78	deleterious	4,57	24,4	0,15	0,45	neutral	0,14	disease	0,62	neutral	0,37	neutral	0,44	1	neutral	0,97	neutral	0,24	neutral	-2	deleterious	0,71	low_impact	-2,51	medium_impact	0,15	medium_impact	0,5	0,5	0,8	75,1	11,59	P	0,57	P	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9906	9906	G	A	MI.8137	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	700	234	G	S	Ggc/Agc	-4,04	0	0	probably_damaging	1	neutral	0,4	neutral	1,82	neutral	-2,83	deleterious	-5,41	medium_impact	2,62	damaging	0,54	damaging	0,02	deleterious	4,34	24,1	0,08	0,35	neutral	0,26	disease	0,71	disease	0,61	disease	0,61	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,76	low_impact	-3,78	medium_impact	0,09	medium_impact	1,17	0,56	0,8	74,33	11,76	N	0,22	N	0,85	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9906	9906	G	T	MI.8138	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	700	234	G	C	Ggc/Tgc	-4,04	0	0	probably_damaging	1	neutral	0,17	neutral	1,73	deleterious	-5,65	deleterious	-8,11	high_impact	3,99	damaging	0,54	damaging	0,02	deleterious	4,33	24	0,05	0,35	disease	0,66	disease	0,86	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	-0,2	high_impact	2,39	0,13	0,8	74,33	11,76	N	0,3	N	0,98	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9906	9906	G	C	MI.8139	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	700	234	G	R	Ggc/Cgc	-4,04	0	0	probably_damaging	1	neutral	0,36	neutral	1,76	deleterious	-4,05	deleterious	-7,21	high_impact	4,2	neutral	0,61	damaging	0,02	deleterious	4,08	23,7	0,04	0,35	neutral	0,32	disease	0,84	disease	0,75	disease	0,77	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	0,05	high_impact	2,58	0,42	0,8	74,33	11,76	N	0,35	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8908	8908	T	G	MI.814	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	382	128	F	V	Ttc/Gtc	-1,95	0	0	benign	0,03	neutral	0,09	neutral	4,4	neutral	-2,05	neutral	-1,94	medium_impact	2,9	neutral	0,89	neutral	0,56	deleterious	2,27	17,99	0,34	0,65	disease	0,59	disease	0,62	disease	0,7	disease	0,73	5	neutral	0,91	deleterious	0,53	neutral	-3	neutral	0,23	medium_impact	0,68	medium_impact	-0,28	medium_impact	1,39	0,48	0,9	19,91	15,56	N	0,41	N	0,86	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9907	9907	G	C	MI.8140	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	701	234	G	A	gGc/gCc	4,29	1	0	probably_damaging	1	neutral	0,53	neutral	1,83	neutral	-2,65	deleterious	-5,41	medium_impact	2,48	damaging	0,56	damaging	0,01	deleterious	3,22	22,7	0,13	0,4	neutral	0,19	disease	0,61	disease	0,7	disease	0,64	3	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,73	low_impact	-3,78	medium_impact	0,22	medium_impact	1,04	0,32	0,8	74,33	11,76	N	0,32	N	0,3	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9907	9907	G	A	MI.8141	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	701	234	G	D	gGc/gAc	4,29	1	0	probably_damaging	1	neutral	0,22	neutral	1,79	deleterious	-3,2	deleterious	-6,31	high_impact	3,64	damaging	0,48	damaging	0,02	deleterious	3,94	23,5	0,03	0,35	neutral	0,35	disease	0,84	disease	0,77	disease	0,77	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	-0,12	high_impact	2,08	0,1	0,8	74,33	11,76	P	0,48	N	0,98	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9907	9907	G	T	MI.8142	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	701	234	G	V	gGc/gTc	4,29	1	0	probably_damaging	1	neutral	0,5	neutral	1,76	deleterious	-4,1	deleterious	-8,11	high_impact	4,54	damaging	0,51	damaging	0,01	deleterious	3,91	23,5	0,05	0,35	neutral	0,26	disease	0,83	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,77	low_impact	-3,78	medium_impact	0,19	high_impact	2,89	0,1	0,8	74,33	11,76	N	0,45	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9909	9909	T	A	MI.8143	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	703	235	F	I	Ttc/Atc	-10,05	0	0	probably_damaging	0,99	neutral	0,38	neutral	1,88	neutral	-2,98	deleterious	-5,2	medium_impact	2,94	neutral	0,79	neutral	0,58	deleterious	4,61	24,4	0,09	0,35	neutral	0,15	disease	0,83	disease	0,68	disease	0,72	4	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,76	low_impact	-2,81	medium_impact	0,07	medium_impact	1,45	0,47	0,8	73,18	12,06	N	0,29	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9909	9909	T	G	MI.8144	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	703	235	F	V	Ttc/Gtc	-10,05	0	0	probably_damaging	1	neutral	0,48	neutral	1,89	neutral	-2,91	deleterious	-6,06	medium_impact	2,21	neutral	0,67	neutral	0,53	deleterious	4,3	24	0,09	0,35	neutral	0,14	disease	0,81	disease	0,67	disease	0,7	4	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,72	low_impact	-3,78	medium_impact	0,17	medium_impact	0,8	0,31	0,8	73,18	12,06	N	0,27	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9909	9909	T	C	MI.8145	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	703	235	F	L	Ttc/Ctc	-10,05	0	0	probably_damaging	0,98	neutral	0,61	neutral	2,03	neutral	-1,33	deleterious	-5,21	low_impact	1,49	damaging	0,51	neutral	0,73	deleterious	4,26	23,9	0,11	0,4	neutral	0,13	disease	0,62	neutral	0,4	neutral	0,41	2	deleterious	0,98	neutral	0,32	neutral	-2	deleterious	0,72	low_impact	-2,51	medium_impact	0,3	medium_impact	0,15	0,59	0,8	73,18	12,06	N	0,36	N	0,92	polymorphism	1	0,09	rs28690056	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9910	9910	T	G	MI.8146	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	704	235	F	C	tTc/tGc	5,68	1	0	probably_damaging	1	neutral	0,17	neutral	1,82	deleterious	-5,55	deleterious	-6,94	high_impact	3,98	neutral	0,71	neutral	0,48	deleterious	4,28	24	0,03	0,35	neutral	0,33	disease	0,84	disease	0,59	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,77	low_impact	-3,78	medium_impact	-0,2	high_impact	2,38	0,24	0,8	73,18	12,06	N	0,47	N	0,98	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9910	9910	T	C	MI.8147	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	704	235	F	S	tTc/tCc	5,68	1	0	probably_damaging	1	neutral	0,42	neutral	1,84	deleterious	-4,01	deleterious	-6,97	high_impact	3,79	neutral	0,84	neutral	0,55	deleterious	4,43	24,2	0,03	0,35	neutral	0,34	disease	0,77	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	0,11	high_impact	2,21	0,34	0,8	73,18	12,06	N	0,5	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9910	9910	T	A	MI.8148	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	704	235	F	Y	tTc/tAc	5,68	1	0	probably_damaging	0,98	neutral	1	neutral	2,06	neutral	-1,14	neutral	-2,43	medium_impact	2,44	neutral	0,61	neutral	0,69	deleterious	4,38	24,1	0,09	0,35	neutral	0,33	disease	0,74	neutral	0,43	disease	0,52	0	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,77	low_impact	-2,51	high_impact	1,9	medium_impact	1	0,56	0,8	73,18	12,06	N	0,49	N	0,8	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9911	9911	C	G	MI.8149	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	705	235	F	L	ttC/ttG	5,68	1	0	probably_damaging	0,98	neutral	0,61	neutral	2,03	neutral	-1,33	deleterious	-5,21	low_impact	1,49	damaging	0,51	neutral	0,73	deleterious	4,51	24,3	0,11	0,4	neutral	0,13	disease	0,62	neutral	0,4	neutral	0,41	2	deleterious	0,98	neutral	0,32	neutral	-2	deleterious	0,72	low_impact	-2,51	medium_impact	0,3	medium_impact	0,15	0,59	0,8	73,18	12,06	N	0,43	N	0,92	polymorphism	1	0,09	rs28615236	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8909	8909	T	C	MI.815	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	383	128	F	S	tTc/tCc	0,36	0,04	0	benign	0,11	deleterious	0	neutral	4,29	deleterious	-3,19	deleterious	-3,96	medium_impact	3,1	neutral	0,82	neutral	0,52	deleterious	2,4	18,82	0,31	0,65	neutral	0,39	disease	0,6	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,45	deleterious	1	neutral	0,28	medium_impact	0,11	low_impact	-1,4	medium_impact	1,56	0,37	0,9	19,91	15,56	N	0,41	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9911	9911	C	A	MI.8150	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	705	235	F	L	ttC/ttA	5,68	1	0	probably_damaging	0,98	neutral	0,61	neutral	2,03	neutral	-1,33	deleterious	-5,21	low_impact	1,49	damaging	0,51	neutral	0,73	deleterious	4,78	24,7	0,11	0,4	neutral	0,13	disease	0,62	neutral	0,4	neutral	0,41	2	deleterious	0,98	neutral	0,32	neutral	-2	deleterious	0,72	low_impact	-2,51	medium_impact	0,3	medium_impact	0,15	0,59	0,8	73,18	12,06	N	0,5	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9912	9912	G	C	MI.8151	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	706	236	E	Q	Gaa/Caa	-2,42	0	0	probably_damaging	0,98	neutral	0,29	neutral	1,79	deleterious	-3,37	deleterious	-2,68	medium_impact	3	damaging	0,53	neutral	0,75	deleterious	3,46	23	0,14	0,4	neutral	0,22	disease	0,82	disease	0,75	disease	0,75	5	deleterious	0,98	neutral	0,16	deleterious	1	deleterious	0,76	low_impact	-2,51	medium_impact	-0,03	medium_impact	1,51	0,5	0,8	73,56	11,71	N	0,42	N	0,01	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9912	9912	G	A	MI.8152	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	706	236	E	K	Gaa/Aaa	-2,42	0	0	probably_damaging	0,98	neutral	0,29	neutral	1,82	neutral	-2,81	deleterious	-3,57	medium_impact	3,08	damaging	0,39	neutral	0,47	deleterious	4,61	24,4	0,05	0,35	neutral	0,19	disease	0,89	disease	0,71	disease	0,76	5	deleterious	0,98	neutral	0,16	deleterious	1	deleterious	0,8	low_impact	-2,51	medium_impact	-0,03	medium_impact	1,58	0,66	0,8	73,56	11,71	P	0,62	P	0,88	polymorphism	1	0,12	rs28580363	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9913	9913	A	G	MI.8153	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	707	236	E	G	gAa/gGa	6,14	1	0	probably_damaging	0,99	neutral	0,33	neutral	1,77	deleterious	-3,92	deleterious	-6,24	high_impact	3,98	damaging	0,49	neutral	0,69	deleterious	4,42	24,2	0,04	0,35	neutral	0,34	disease	0,85	disease	0,75	disease	0,77	5	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-2,81	medium_impact	0,02	high_impact	2,38	0,24	0,8	73,56	11,71	P	0,56	P	0,83	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9913	9913	A	C	MI.8154	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	707	236	E	A	gAa/gCa	6,14	1	0	probably_damaging	0,98	neutral	0,51	neutral	1,8	deleterious	-3,21	deleterious	-5,35	medium_impact	3,49	damaging	0,56	neutral	0,63	deleterious	3,92	23,5	0,05	0,35	neutral	0,19	disease	0,8	disease	0,73	disease	0,71	4	deleterious	0,98	neutral	0,27	deleterious	1	deleterious	0,76	low_impact	-2,51	medium_impact	0,2	medium_impact	1,95	0,3	0,8	73,56	11,71	N	0,5	N	0,59	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9913	9913	A	T	MI.8155	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	707	236	E	V	gAa/gTa	6,14	1	0	probably_damaging	0,99	neutral	0,5	neutral	1,76	deleterious	-3,98	deleterious	-6,24	medium_impact	3,49	damaging	0,47	neutral	0,59	deleterious	4,42	24,2	0,03	0,35	neutral	0,37	disease	0,91	disease	0,75	disease	0,79	6	deleterious	0,99	neutral	0,26	deleterious	1	deleterious	0,81	low_impact	-2,81	medium_impact	0,19	medium_impact	1,95	0,23	0,8	73,56	11,71	P	0,59	P	0,9	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9914	9914	A	T	MI.8156	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	708	236	E	D	gaA/gaT	8,69	1	0	probably_damaging	0,92	neutral	0,2	neutral	1,83	neutral	-2,73	deleterious	-2,68	medium_impact	3,33	damaging	0,53	neutral	0,57	deleterious	4,01	23,6	0,2	0,45	neutral	0,3	disease	0,81	disease	0,68	disease	0,71	4	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,75	low_impact	-1,9	medium_impact	-0,15	medium_impact	1,8	0,41	0,8	73,56	11,71	P	0,61	P	0,8	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9914	9914	A	C	MI.8157	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	708	236	E	D	gaA/gaC	8,69	1	0	probably_damaging	0,92	neutral	0,2	neutral	1,83	neutral	-2,73	deleterious	-2,68	medium_impact	3,33	damaging	0,53	neutral	0,57	deleterious	3,88	23,5	0,2	0,45	neutral	0,3	disease	0,81	disease	0,68	disease	0,71	4	neutral	0,95	neutral	0,14	deleterious	1	deleterious	0,75	low_impact	-1,9	medium_impact	-0,15	medium_impact	1,8	0,41	0,8	73,56	11,71	P	0,58	P	0,8	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9915	9915	G	A	MI.8158	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	709	237	A	T	Gcc/Acc	1,75	1	0	probably_damaging	1	neutral	0,42	neutral	2,41	neutral	-1,69	deleterious	-3,51	medium_impact	2,69	damaging	0,56	damaging	0,06	deleterious	4,45	24,2	0,11	0,4	neutral	0,23	disease	0,76	neutral	0,41	disease	0,52	0	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	0,11	medium_impact	1,23	0,56	0,8	73,95	11,92	N	0,38	N	0,86	polymorphism	1	0,07	.	.	.	.	.	.	COSM1155710	.	.	.	.	.	.	.	.
chrM	9915	9915	G	T	MI.8159	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	709	237	A	S	Gcc/Tcc	1,75	1	0	probably_damaging	1	neutral	0,42	neutral	2,39	neutral	-2,08	deleterious	-2,6	medium_impact	2,88	damaging	0,54	damaging	0,08	deleterious	3,83	23,4	0,13	0,4	neutral	0,25	disease	0,74	neutral	0,39	disease	0,52	0	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,78	low_impact	-3,78	medium_impact	0,11	medium_impact	1,4	0,33	0,8	73,95	11,92	N	0,36	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8909	8909	T	G	MI.816	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	383	128	F	C	tTc/tGc	0,36	0,04	0	possibly_damaging	0,53	deleterious	0	neutral	4,26	deleterious	-4,69	deleterious	-3,45	medium_impact	3,45	neutral	0,89	neutral	0,46	deleterious	3,73	23,3	0,29	0,65	disease	0,87	disease	0,7	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,24	deleterious	4	deleterious	0,58	medium_impact	-0,81	low_impact	-1,4	medium_impact	1,86	0,3	0,9	19,91	15,56	N	0,41	N	0,81	polymorphism	0,99	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9915	9915	G	C	MI.8160	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	709	237	A	P	Gcc/Ccc	1,75	1	0	probably_damaging	1	neutral	0,2	neutral	2,36	deleterious	-3,08	deleterious	-4,42	high_impact	3,71	damaging	0,48	damaging	0,06	deleterious	4	23,6	0,03	0,35	neutral	0,33	disease	0,85	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	-0,15	high_impact	2,14	0,31	0,8	73,95	11,92	N	0,42	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9916	9916	C	T	MI.8161	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	710	237	A	V	gCc/gTc	9,15	1	0	probably_damaging	1	neutral	0,49	neutral	2,48	neutral	-0,83	deleterious	-3,54	medium_impact	2,38	damaging	0,48	damaging	0,06	deleterious	4,54	24,3	0,09	0,35	neutral	0,15	disease	0,81	disease	0,55	disease	0,68	4	deleterious	0,99	neutral	0,25	deleterious	1	deleterious	0,74	low_impact	-3,78	medium_impact	0,18	medium_impact	0,95	0,5	0,8	73,95	11,92	N	0,48	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9916	9916	C	A	MI.8162	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	710	237	A	D	gCc/gAc	9,15	1	0	probably_damaging	1	neutral	0,22	neutral	2,35	deleterious	-3,6	deleterious	-5,29	high_impact	4,41	damaging	0,57	damaging	0,06	deleterious	4,74	24,7	0,03	0,35	disease	0,52	disease	0,9	disease	0,67	disease	0,76	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,12	high_impact	2,77	0,26	0,8	73,95	11,92	P	0,54	P	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9916	9916	C	G	MI.8163	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	710	237	A	G	gCc/gGc	9,15	1	0	probably_damaging	0,99	neutral	0,34	neutral	2,37	neutral	-2,54	deleterious	-3,53	medium_impact	2,84	damaging	0,53	damaging	0,11	deleterious	4,11	23,7	0,1	0,4	neutral	0,29	disease	0,75	disease	0,54	disease	0,6	2	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,76	low_impact	-2,81	medium_impact	0,03	medium_impact	1,36	0,44	0,8	73,95	11,92	N	0,46	N	0,67	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9918	9918	G	T	MI.8164	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	712	238	A	S	Gcc/Tcc	-11,21	0	0	probably_damaging	1	neutral	0,39	neutral	2,01	neutral	-1,77	deleterious	-2,66	low_impact	1,73	damaging	0,43	damaging	0,17	deleterious	3,85	23,4	0,15	0,4	neutral	0,19	disease	0,68	neutral	0,37	neutral	0,43	1	deleterious	1	neutral	0,2	neutral	-2	deleterious	0,77	low_impact	-3,78	medium_impact	0,08	medium_impact	0,37	0,34	0,8	73,95	11,73	N	0,39	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9918	9918	G	A	MI.8165	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	712	238	A	T	Gcc/Acc	-11,21	0	0	probably_damaging	1	neutral	0,38	neutral	2	neutral	-1,88	deleterious	-3,55	medium_impact	2,51	damaging	0,6	damaging	0,06	deleterious	4,38	24,1	0,12	0,4	neutral	0,15	disease	0,78	disease	0,65	disease	0,54	1	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,77	low_impact	-3,78	medium_impact	0,07	medium_impact	1,07	0,65	0,8	73,95	11,73	N	0,23	N	0,86	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9918	9918	G	C	MI.8166	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	712	238	A	P	Gcc/Ccc	-11,21	0	0	probably_damaging	1	neutral	0,2	neutral	1,89	deleterious	-4	deleterious	-4,44	high_impact	3,85	damaging	0,53	damaging	0,06	deleterious	4,01	23,6	0,03	0,35	disease	0,52	disease	0,84	disease	0,78	disease	0,78	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,15	high_impact	2,27	0,31	0,8	73,95	11,73	N	0,37	N	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9919	9919	C	G	MI.8167	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	713	238	A	G	gCc/gGc	7,3	1	0	probably_damaging	0,99	neutral	0,34	neutral	1,99	neutral	-1,97	deleterious	-3,54	medium_impact	2,68	damaging	0,48	damaging	0,14	deleterious	4,15	23,8	0,12	0,4	neutral	0,31	disease	0,72	disease	0,55	disease	0,52	0	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,76	low_impact	-2,81	medium_impact	0,03	medium_impact	1,22	0,42	0,8	73,95	11,73	N	0,49	N	0,67	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9919	9919	C	T	MI.8168	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	713	238	A	V	gCc/gTc	7,3	1	0	probably_damaging	1	neutral	0,49	neutral	1,93	neutral	-2,87	deleterious	-3,55	medium_impact	2,29	damaging	0,53	damaging	0,05	deleterious	4,64	24,5	0,1	0,4	neutral	0,17	disease	0,83	disease	0,65	disease	0,71	4	deleterious	0,99	neutral	0,25	deleterious	1	deleterious	0,75	low_impact	-3,78	medium_impact	0,18	medium_impact	0,87	0,56	0,8	73,95	11,73	N	0,45	N	0,87	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9919	9919	C	A	MI.8169	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	713	238	A	D	gCc/gAc	7,3	1	0	probably_damaging	1	neutral	0,2	neutral	1,89	deleterious	-4,06	deleterious	-5,32	high_impact	4,4	neutral	0,63	damaging	0,05	deleterious	4,65	24,5	0,03	0,35	neutral	0,45	disease	0,9	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	-0,15	high_impact	2,76	0,26	0,8	73,95	11,73	P	0,58	P	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8909	8909	T	A	MI.817	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	383	128	F	Y	tTc/tAc	0,36	0,04	0	benign	0,11	deleterious	0	neutral	4,4	deleterious	-3,01	neutral	-1,64	medium_impact	2,64	neutral	0,89	neutral	0,48	deleterious	2,41	18,89	0,39	0,65	disease	0,78	neutral	0,49	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,45	deleterious	1	neutral	0,31	medium_impact	0,11	low_impact	-1,4	medium_impact	1,17	0,61	0,9	19,91	15,56	N	0,42	N	0,75	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9921	9921	G	C	MI.8170	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	715	239	A	P	Gcc/Ccc	-9,59	0	0	possibly_damaging	0,8	neutral	0,2	neutral	2,14	deleterious	-3,42	deleterious	-4,19	high_impact	4,2	damaging	0,58	neutral	0,37	deleterious	3,96	23,6	0,03	0,35	disease	0,52	disease	0,86	disease	0,79	disease	0,79	6	neutral	0,88	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-1,45	medium_impact	-0,15	high_impact	2,58	0,41	0,8	75,1	11,16	N	0,48	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9921	9921	G	A	MI.8171	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	715	239	A	T	Gcc/Acc	-9,59	0	0	benign	0,02	neutral	0,39	neutral	2,2	neutral	-1,33	deleterious	-3,19	medium_impact	2,77	damaging	0,44	neutral	0,48	deleterious	2,47	19,3	0,08	0,35	neutral	0,28	disease	0,8	disease	0,63	disease	0,65	3	neutral	0,59	deleterious	0,69	neutral	-3	neutral	0,26	medium_impact	0,77	medium_impact	0,08	medium_impact	1,3	0,73	0,85	75,1	11,16	N	0,47	N	0,86	polymorphism	1	0,08	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	9921	9921	G	T	MI.8172	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	715	239	A	S	Gcc/Tcc	-9,59	0	0	benign	0,34	neutral	0,4	neutral	2,18	neutral	-1,75	neutral	-2,47	low_impact	1,76	damaging	0,48	neutral	0,7	deleterious	3,64	23,2	0,15	0,4	neutral	0,13	disease	0,74	neutral	0,48	disease	0,51	0	neutral	0,53	deleterious	0,53	neutral	-6	neutral	0,31	medium_impact	-0,59	medium_impact	0,09	medium_impact	0,4	0,38	0,8	75,1	11,16	N	0,41	N	0,89	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9922	9922	C	G	MI.8173	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	716	239	A	G	gCc/gGc	4,29	1	0	benign	0,21	neutral	0,32	neutral	2,15	neutral	-2,68	deleterious	-3,42	medium_impact	2,67	neutral	0,61	neutral	0,55	deleterious	3,91	23,5	0,13	0,4	neutral	0,3	disease	0,79	disease	0,68	disease	0,7	4	neutral	0,62	deleterious	0,56	neutral	-3	neutral	0,32	medium_impact	-0,31	medium_impact	0,01	medium_impact	1,21	0,54	0,8	75,1	11,16	N	0,48	N	0,67	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9922	9922	C	T	MI.8174	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	716	239	A	V	gCc/gTc	4,29	1	0	benign	0,24	neutral	0,54	neutral	2,33	neutral	0,09	deleterious	-3,09	medium_impact	2,15	damaging	0,49	neutral	0,45	deleterious	4,46	24,2	0,07	0,35	neutral	0,24	disease	0,81	disease	0,65	disease	0,55	1	neutral	0,35	deleterious	0,65	neutral	-3	deleterious	0,49	medium_impact	-0,38	medium_impact	0,23	medium_impact	0,74	0,63	0,8	75,1	11,16	P	0,5	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9922	9922	C	A	MI.8175	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	716	239	A	D	gCc/gAc	4,29	1	0	possibly_damaging	0,68	neutral	0,2	neutral	2,14	deleterious	-3,2	deleterious	-5	high_impact	4,2	neutral	0,63	neutral	0,39	deleterious	4,61	24,4	0,03	0,35	neutral	0,45	disease	0,91	disease	0,77	disease	0,81	6	neutral	0,83	neutral	0,26	deleterious	1	deleterious	0,73	low_impact	-1,19	medium_impact	-0,15	high_impact	2,58	0,41	0,8	75,1	11,16	P	0,62	P	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9924	9924	T	C	MI.8176	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	718	240	W	R	Tga/Cga	-7,97	0	0	probably_damaging	1	neutral	0,09	neutral	2,16	neutral	-2,76	deleterious	-12,07	high_impact	3,88	damaging	0,59	damaging	0,05	deleterious	3,66	23,2	0,03	0,35	neutral	0,37	disease	0,9	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	-0,38	high_impact	2,3	0,17	0,8	73,56	11,87	N	0,41	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9924	9924	T	G	MI.8177	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	718	240	W	G	Tga/Gga	-7,97	0	0	probably_damaging	0,99	neutral	0,09	neutral	2,15	neutral	-2,9	deleterious	-11,21	high_impact	3,54	neutral	0,6	damaging	0,02	deleterious	4,04	23,7	0,05	0,35	neutral	0,39	disease	0,85	disease	0,72	disease	0,77	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,78	low_impact	-2,81	medium_impact	-0,38	medium_impact	1,99	0,12	0,8	73,56	11,87	N	0,3	N	0,98	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9925	9925	G	T	MI.8178	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	719	240	W	L	tGa/tTa	7,3	1	0	probably_damaging	0,99	neutral	0,17	neutral	2,41	neutral	1,42	deleterious	-11,21	medium_impact	2,09	damaging	0,51	damaging	0,02	deleterious	4,44	24,2	0,09	0,35	neutral	0,17	disease	0,78	disease	0,57	disease	0,5	0	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,72	low_impact	-2,81	medium_impact	-0,2	medium_impact	0,69	0,13	0,8	73,56	11,87	N	0,38	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9925	9925	G	C	MI.8179	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	719	240	W	S	tGa/tCa	7,3	1	0	probably_damaging	1	neutral	0,14	neutral	2,18	neutral	-1,73	deleterious	-12,07	high_impact	4,43	neutral	0,67	damaging	0,02	deleterious	4,23	23,9	0,05	0,35	neutral	0,26	disease	0,89	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	-0,26	high_impact	2,79	0,15	0,8	73,56	11,87	N	0,47	N	0,97	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8910	8910	C	G	MI.818	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	384	128	F	L	ttC/ttG	7,53	0,97	0	benign	0	neutral	1	neutral	4,64	neutral	-0,75	neutral	0,09	neutral_impact	-0,74	neutral	0,93	neutral	0,95	neutral	-0,25	0,85	0,44	0,65	neutral	0,26	neutral	0,12	neutral	0,24	neutral	0,29	4	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,09	high_impact	1,98	low_impact	-1,73	0,73	0,9	19,91	15,56	N	0,5	N	0,07	polymorphism	0,96	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9926	9926	A	T	MI.8180	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	720	240	W	C	tgA/tgT	9,15	1	0	probably_damaging	1	neutral	0,11	neutral	2,14	deleterious	-3,05	deleterious	-11,21	high_impact	4,43	neutral	0,67	damaging	0,02	deleterious	4,22	23,9	0,04	0,35	neutral	0,44	disease	0,9	disease	0,74	disease	0,8	6	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,33	high_impact	2,79	0,19	0,8	73,56	11,87	P	0,52	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9926	9926	A	C	MI.8181	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	720	240	W	C	tgA/tgC	9,15	1	0	probably_damaging	1	neutral	0,11	neutral	2,14	deleterious	-3,05	deleterious	-11,21	high_impact	4,43	neutral	0,67	damaging	0,02	deleterious	4,11	23,8	0,04	0,35	neutral	0,44	disease	0,9	disease	0,74	disease	0,8	6	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,33	high_impact	2,79	0,19	0,8	73,56	11,87	P	0,52	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9927	9927	T	G	MI.8182	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	721	241	Y	D	Tac/Gac	3,83	1	0	probably_damaging	1	deleterious	0,04	neutral	1,08	deleterious	-9,99	deleterious	-8,62	high_impact	4,3	neutral	0,6	damaging	0,01	deleterious	4,09	23,7	0,02	0,35	disease	0,88	disease	0,84	disease	0,82	disease	0,87	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-3,78	medium_impact	-0,6	high_impact	2,67	0,15	0,8	73,95	11,49	N	0,47	N	0,99	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9927	9927	T	C	MI.8183	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	721	241	Y	H	Tac/Cac	3,83	1	0	probably_damaging	1	neutral	0,54	neutral	1,1	deleterious	-7,43	deleterious	-4,31	high_impact	4,11	damaging	0,56	damaging	0,02	deleterious	3,72	23,3	0,05	0,35	disease	0,7	disease	0,78	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	0,23	high_impact	2,5	0,19	0,8	73,95	11,49	N	0,5	N	0,97	polymorphism	1	0,42	.	.	.	.	.	.	COSM1155712	.	.	.	.	.	.	.	.
chrM	9927	9927	T	A	MI.8184	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	721	241	Y	N	Tac/Aac	3,83	1	0	probably_damaging	1	neutral	0,07	neutral	1,08	deleterious	-8,78	deleterious	-7,76	high_impact	4,66	damaging	0,59	damaging	0,01	deleterious	4,17	23,8	0,02	0,35	disease	0,81	disease	0,86	disease	0,77	disease	0,82	6	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,45	high_impact	2,99	0,15	0,8	73,95	11,49	P	0,54	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9928	9928	A	G	MI.8185	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	722	241	Y	C	tAc/tGc	7,3	1	0	probably_damaging	1	deleterious	0,04	neutral	1,08	deleterious	-10,17	deleterious	-7,76	high_impact	4,66	neutral	0,64	damaging	0,01	deleterious	3,51	23,1	0,02	0,35	disease	0,89	disease	0,85	disease	0,79	disease	0,86	7	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,85	low_impact	-3,78	medium_impact	-0,6	high_impact	2,99	0,15	0,8	73,95	11,49	P	0,55	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9928	9928	A	C	MI.8186	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	722	241	Y	S	tAc/tCc	7,3	1	0	probably_damaging	1	neutral	0,09	neutral	1,08	deleterious	-8,53	deleterious	-7,76	high_impact	4,66	neutral	0,61	damaging	0,02	deleterious	3,71	23,3	0,02	0,35	disease	0,75	disease	0,8	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,38	high_impact	2,99	0,15	0,8	73,95	11,49	P	0,55	P	0,96	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9928	9928	A	T	MI.8187	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	722	241	Y	F	tAc/tTc	7,3	1	0	probably_damaging	0,99	neutral	0,42	neutral	1,39	deleterious	-3,93	deleterious	-3,45	medium_impact	2,9	damaging	0,58	damaging	0,02	deleterious	3,38	23	0,11	0,4	neutral	0,31	disease	0,81	disease	0,72	disease	0,74	5	deleterious	0,99	neutral	0,22	deleterious	1	deleterious	0,78	low_impact	-2,81	medium_impact	0,11	medium_impact	1,42	0,55	0,8	73,95	11,49	N	0,44	N	0,72	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9930	9930	T	C	MI.8188	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	724	242	W	R	Tgg/Cgg	-1,49	0	0	probably_damaging	1	neutral	0,11	neutral	-0,75	deleterious	-10,24	deleterious	-12,07	high_impact	3,98	neutral	0,66	damaging	0,03	deleterious	3,74	23,3	0,02	0,35	disease	0,64	disease	0,93	disease	0,8	disease	0,86	7	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	-0,33	high_impact	2,38	0,17	0,8	73,95	11,58	N	0,37	N	0,99	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9930	9930	T	G	MI.8189	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	724	242	W	G	Tgg/Ggg	-1,49	0	0	probably_damaging	1	neutral	0,19	neutral	-0,76	deleterious	-11,81	deleterious	-11,21	high_impact	4,33	neutral	0,61	damaging	0,02	deleterious	4,02	23,6	0,03	0,35	disease	0,65	disease	0,88	disease	0,78	disease	0,82	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	-0,17	high_impact	2,7	0,12	0,8	73,95	11,58	N	0,36	N	0,98	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8910	8910	C	A	MI.819	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	384	128	F	L	ttC/ttA	7,53	0,97	0	benign	0	neutral	1	neutral	4,64	neutral	-0,75	neutral	0,09	neutral_impact	-0,74	neutral	0,93	neutral	0,95	deleterious	0,05	3,06	0,44	0,65	neutral	0,26	neutral	0,12	neutral	0,24	neutral	0,29	4	neutral	0	deleterious	1	neutral	-6	neutral	0,12	high_impact	2,09	high_impact	1,98	low_impact	-1,73	0,73	0,9	19,91	15,56	N	0,51	P	0,07	polymorphism	0,96	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9931	9931	G	C	MI.8190	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	725	242	W	S	tGg/tCg	7,3	1	0	probably_damaging	1	neutral	0,13	neutral	-0,76	deleterious	-11,8	deleterious	-12,07	high_impact	4,33	neutral	0,65	damaging	0,02	deleterious	4,15	23,8	0,02	0,35	disease	0,52	disease	0,91	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,84	low_impact	-3,78	medium_impact	-0,28	high_impact	2,7	0,13	0,8	73,95	11,58	N	0,41	N	0,97	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9931	9931	G	T	MI.8191	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	725	242	W	L	tGg/tTg	7,3	1	0	probably_damaging	1	neutral	0,21	neutral	-0,75	deleterious	-9,37	deleterious	-11,21	high_impact	3,63	neutral	0,61	damaging	0,02	deleterious	4,39	24,1	0,03	0,35	neutral	0,37	disease	0,87	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	-0,14	high_impact	2,07	0,1	0,8	73,95	11,58	N	0,41	N	1	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9932	9932	G	T	MI.8192	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	726	242	W	C	tgG/tgT	6,14	1	0,03	probably_damaging	1	neutral	0,06	neutral	-0,76	deleterious	-12,02	deleterious	-11,21	high_impact	4,33	neutral	0,66	damaging	0,02	deleterious	4,29	24	0,03	0,35	disease	0,77	disease	0,92	disease	0,79	disease	0,82	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	-0,49	high_impact	2,7	0,13	0,8	73,95	11,58	N	0,42	N	1	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9932	9932	G	C	MI.8193	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	726	242	W	C	tgG/tgC	6,14	1	0,03	probably_damaging	1	neutral	0,06	neutral	-0,76	deleterious	-12,02	deleterious	-11,21	high_impact	4,33	neutral	0,66	damaging	0,02	deleterious	4,14	23,8	0,03	0,35	disease	0,77	disease	0,92	disease	0,79	disease	0,82	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	-0,49	high_impact	2,7	0,13	0,8	73,95	11,58	N	0,43	N	1	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9933	9933	C	T	MI.8194	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	727	243	H	Y	Cat/Tat	3,14	1	0	probably_damaging	0,96	neutral	1	neutral	1,21	deleterious	-4,58	deleterious	-5,16	high_impact	4,66	neutral	0,66	damaging	0,02	deleterious	3,91	23,5	0,06	0,35	disease	0,6	disease	0,91	disease	0,75	disease	0,82	6	neutral	0,96	deleterious	0,52	deleterious	2	deleterious	0,84	low_impact	-2,21	high_impact	1,9	high_impact	2,99	0,29	0,8	73,56	11,37	N	0,5	N	0,99	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9933	9933	C	A	MI.8195	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	727	243	H	N	Cat/Aat	3,14	1	0	probably_damaging	0,98	neutral	0,25	neutral	1,13	deleterious	-6,43	deleterious	-6,02	high_impact	4,66	neutral	0,62	damaging	0,02	deleterious	4,06	23,7	0,11	0,4	disease	0,66	disease	0,89	disease	0,74	disease	0,8	6	deleterious	0,98	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-2,51	medium_impact	-0,08	high_impact	2,99	0,26	0,8	73,56	11,37	P	0,53	P	0,96	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9933	9933	C	G	MI.8196	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	727	243	H	D	Cat/Gat	3,14	1	0	probably_damaging	0,98	neutral	0,31	neutral	1,13	deleterious	-6,89	deleterious	-7,73	high_impact	3,96	neutral	0,64	damaging	0,01	deleterious	4	23,6	0,05	0,35	disease	0,66	disease	0,86	disease	0,8	disease	0,83	7	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-2,51	medium_impact	-0,01	high_impact	2,37	0,19	0,8	73,56	11,37	N	0,46	N	0,98	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9934	9934	A	C	MI.8197	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	728	243	H	P	cAt/cCt	4,29	1	0	probably_damaging	0,99	neutral	0,17	neutral	1,11	deleterious	-8,12	deleterious	-8,6	high_impact	4,66	neutral	0,62	damaging	0,02	deleterious	3,41	23	0,03	0,35	disease	0,78	disease	0,89	disease	0,82	disease	0,86	7	deleterious	0,99	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-2,81	medium_impact	-0,2	high_impact	2,99	0,2	0,8	73,56	11,37	P	0,54	P	0,98	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9934	9934	A	T	MI.8198	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	728	243	H	L	cAt/cTt	4,29	1	0	probably_damaging	0,97	neutral	0,61	neutral	1,13	deleterious	-6,59	deleterious	-9,46	high_impact	3,76	damaging	0,59	damaging	0,02	deleterious	4,02	23,6	0,04	0,35	disease	0,56	disease	0,92	disease	0,75	disease	0,82	6	neutral	0,96	neutral	0,32	deleterious	2	deleterious	0,83	low_impact	-2,34	medium_impact	0,3	high_impact	2,19	0,25	0,8	73,56	11,37	N	0,45	N	0,96	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9934	9934	A	G	MI.8199	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	728	243	H	R	cAt/cGt	4,29	1	0	probably_damaging	0,97	neutral	0,33	neutral	1,14	deleterious	-5,97	deleterious	-6,88	high_impact	4,31	neutral	0,73	damaging	0,02	deleterious	3,17	22,7	0,05	0,35	disease	0,59	disease	0,9	disease	0,78	disease	0,82	6	neutral	0,97	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-2,34	medium_impact	0,02	high_impact	2,68	0,4	0,8	73,56	11,37	N	0,5	N	0,99	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8563	8563	A	T	MI.82	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	37	13	T	S	Aca/Tca	-8,89	0	0,12	probably_damaging	0,99	neutral	0,54	neutral	4,61	neutral	-0,58	neutral	-1,82	low_impact	0,94	neutral	0,88	neutral	0,96	neutral	1,76	14,75	0,5	0,65	neutral	0,24	neutral	0,37	neutral	0,39	neutral	0,44	1	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,64	low_impact	-2,65	medium_impact	0,33	medium_impact	-0,29	0,73	0,9	15,49	16,77	N	0,35	N	0,37	polymorphism	1	0,03	rs386829041	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8911	8911	T	G	MI.820	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	385	129	L	V	Tta/Gta	-9,59	0	0	probably_damaging	0,99	neutral	0,68	neutral	4,41	neutral	0,64	deleterious	-2,76	low_impact	1,5	neutral	0,72	damaging	0,15	deleterious	3,42	23	0,49	0,65	neutral	0,31	neutral	0,25	neutral	0,31	neutral	0,43	1	deleterious	0,99	neutral	0,35	neutral	-2	deleterious	0,72	low_impact	-2,65	medium_impact	0,48	medium_impact	0,19	0,54	0,9	49,12	8,65	N	0,24	N	0,87	polymorphism	0,96	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9935	9935	T	G	MI.8200	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	729	243	H	Q	caT/caG	8,69	1	0	probably_damaging	0,98	neutral	0,24	neutral	1,14	deleterious	-6,26	deleterious	-6,88	high_impact	4,66	neutral	0,65	damaging	0,02	deleterious	3,6	23,2	0,06	0,35	disease	0,65	disease	0,81	disease	0,75	disease	0,78	6	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,8	low_impact	-2,51	medium_impact	-0,09	high_impact	2,99	0,37	0,8	73,56	11,37	P	0,6	P	0,94	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9935	9935	T	A	MI.8201	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	729	243	H	Q	caT/caA	8,69	1	0	probably_damaging	0,98	neutral	0,24	neutral	1,14	deleterious	-6,26	deleterious	-6,88	high_impact	4,66	neutral	0,65	damaging	0,02	deleterious	3,72	23,3	0,06	0,35	disease	0,65	disease	0,81	disease	0,75	disease	0,78	6	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,8	low_impact	-2,51	medium_impact	-0,09	high_impact	2,99	0,37	0,8	73,56	11,37	P	0,61	P	0,94	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9936	9936	T	C	MI.8202	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	730	244	F	L	Ttt/Ctt	-1,72	0	0	probably_damaging	0,98	neutral	0,58	neutral	1,61	deleterious	-3,03	deleterious	-5,17	high_impact	3,51	neutral	0,65	damaging	0,03	deleterious	4,33	24	0,03	0,35	neutral	0,36	disease	0,83	disease	0,61	disease	0,71	4	deleterious	0,98	neutral	0,3	deleterious	2	deleterious	0,75	low_impact	-2,51	medium_impact	0,27	medium_impact	1,96	0,43	0,8	73,56	11,67	N	0,23	N	0,92	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9936	9936	T	A	MI.8203	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	730	244	F	I	Ttt/Att	-1,72	0	0	probably_damaging	0,99	neutral	0,31	neutral	1,48	deleterious	-4,56	deleterious	-5,17	high_impact	4,12	neutral	0,68	damaging	0,02	deleterious	4,79	24,7	0,05	0,35	neutral	0,43	disease	0,87	disease	0,6	disease	0,73	5	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,8	low_impact	-2,81	medium_impact	-0,01	high_impact	2,51	0,45	0,8	73,56	11,67	N	0,34	N	0,96	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9936	9936	T	G	MI.8204	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	730	244	F	V	Ttt/Gtt	-1,72	0	0	probably_damaging	1	neutral	0,8	neutral	1,48	deleterious	-4,56	deleterious	-6,03	medium_impact	3,08	damaging	0,59	damaging	0,02	deleterious	4,26	23,9	0,04	0,35	neutral	0,28	disease	0,84	disease	0,61	disease	0,54	1	deleterious	1	neutral	0,4	deleterious	1	deleterious	0,74	low_impact	-3,78	medium_impact	0,54	medium_impact	1,58	0,38	0,8	73,56	11,67	N	0,2	N	0,97	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9937	9937	T	C	MI.8205	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	731	244	F	S	tTt/tCt	5,68	1	0	probably_damaging	1	neutral	0,27	neutral	1,41	deleterious	-7,37	deleterious	-6,89	high_impact	4,32	neutral	0,7	damaging	0,03	deleterious	4,33	24	0,03	0,35	disease	0,52	disease	0,84	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	-0,06	high_impact	2,69	0,19	0,8	73,56	11,67	N	0,47	N	0,96	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9937	9937	T	G	MI.8206	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	731	244	F	C	tTt/tGt	5,68	1	0	probably_damaging	1	neutral	0,12	neutral	1,41	deleterious	-7,98	deleterious	-6,89	high_impact	4,66	neutral	0,72	damaging	0,02	deleterious	4,2	23,9	0,02	0,35	disease	0,76	disease	0,87	disease	0,66	disease	0,74	5	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	-0,3	high_impact	2,99	0,21	0,8	73,56	11,67	P	0,52	P	0,98	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9937	9937	T	A	MI.8207	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	731	244	F	Y	tTt/tAt	5,68	1	0	probably_damaging	0,98	neutral	0,78	neutral	1,44	deleterious	-5,43	deleterious	-2,58	high_impact	4,32	neutral	0,71	damaging	0,03	deleterious	4,25	23,9	0,09	0,35	disease	0,5	disease	0,82	disease	0,62	disease	0,71	4	deleterious	0,98	neutral	0,4	deleterious	2	deleterious	0,79	low_impact	-2,51	medium_impact	0,51	high_impact	2,69	0,49	0,8	73,56	11,67	N	0,5	N	0,8	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9938	9938	T	G	MI.8208	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	732	244	F	L	ttT/ttG	7,3	1	0,01	probably_damaging	0,98	neutral	0,58	neutral	1,61	deleterious	-3,03	deleterious	-5,17	high_impact	3,51	neutral	0,65	damaging	0,03	deleterious	4,48	24,2	0,03	0,35	neutral	0,36	disease	0,83	disease	0,61	disease	0,71	4	deleterious	0,98	neutral	0,3	deleterious	2	deleterious	0,75	low_impact	-2,51	medium_impact	0,27	medium_impact	1,96	0,43	0,8	73,56	11,67	N	0,44	N	0,92	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9938	9938	T	A	MI.8209	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	732	244	F	L	ttT/ttA	7,3	1	0,01	probably_damaging	0,98	neutral	0,58	neutral	1,61	deleterious	-3,03	deleterious	-5,17	high_impact	3,51	neutral	0,65	damaging	0,03	deleterious	4,58	24,4	0,03	0,35	neutral	0,36	disease	0,83	disease	0,61	disease	0,71	4	deleterious	0,98	neutral	0,3	deleterious	2	deleterious	0,75	low_impact	-2,51	medium_impact	0,27	medium_impact	1,96	0,43	0,8	73,56	11,67	N	0,45	N	0,92	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8911	8911	T	A	MI.821	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	385	129	L	M	Tta/Ata	-9,59	0	0	probably_damaging	1	neutral	0,13	neutral	4,13	neutral	-1,37	neutral	-1,84	medium_impact	2,56	neutral	0,78	damaging	0,16	deleterious	3,56	23,1	0,36	0,65	disease	0,69	neutral	0,49	disease	0,68	disease	0,59	2	deleterious	1	neutral	0,07	deleterious	1	deleterious	0,77	low_impact	-3,6	medium_impact	-0,18	medium_impact	1,1	0,67	0,9	49,12	8,65	N	0,31	N	0,96	polymorphism	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9939	9939	G	T	MI.8210	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	733	245	V	L	Gta/Tta	-5,89	0	0	probably_damaging	0,92	neutral	0,67	neutral	1,89	neutral	-2,88	deleterious	-2,58	medium_impact	3,29	neutral	0,61	damaging	0,02	deleterious	3,81	23,4	0,11	0,4	neutral	0,27	disease	0,8	disease	0,66	disease	0,54	1	neutral	0,91	neutral	0,38	deleterious	1	deleterious	0,75	low_impact	-1,9	medium_impact	0,37	medium_impact	1,77	0,24	0,8	73,95	11,87	N	0,2	N	0,68	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9939	9939	G	C	MI.8211	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	733	245	V	L	Gta/Cta	-5,89	0	0	probably_damaging	0,92	neutral	0,67	neutral	1,89	neutral	-2,88	deleterious	-2,58	medium_impact	3,29	neutral	0,61	damaging	0,02	deleterious	3,65	23,2	0,11	0,4	neutral	0,27	disease	0,8	disease	0,66	disease	0,54	1	neutral	0,91	neutral	0,38	deleterious	1	deleterious	0,75	low_impact	-1,9	medium_impact	0,37	medium_impact	1,77	0,24	0,8	73,95	11,87	N	0,2	N	0,68	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9939	9939	G	A	MI.8212	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	733	245	V	M	Gta/Ata	-5,89	0	0	probably_damaging	1	neutral	0,22	neutral	1,58	deleterious	-5,28	deleterious	-2,58	high_impact	4,64	neutral	0,65	damaging	0,01	deleterious	3,81	23,4	0,07	0,35	disease	0,63	disease	0,75	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	-0,12	high_impact	2,98	0,51	0,8	73,95	11,87	N	0,49	N	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9940	9940	T	C	MI.8213	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	734	245	V	A	gTa/gCa	9,15	1	0	probably_damaging	0,99	neutral	0,54	neutral	1,63	deleterious	-5,53	deleterious	-3,44	high_impact	4,29	neutral	0,61	damaging	0,05	deleterious	3,68	23,3	0,05	0,35	disease	0,56	disease	0,76	disease	0,72	disease	0,74	5	deleterious	0,99	neutral	0,28	deleterious	2	deleterious	0,8	low_impact	-2,81	medium_impact	0,23	high_impact	2,66	0,12	0,8	73,95	11,87	P	0,54	P	0,39	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9940	9940	T	A	MI.8214	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	734	245	V	E	gTa/gAa	9,15	1	0	probably_damaging	0,99	neutral	0,26	neutral	1,56	deleterious	-7,65	deleterious	-5,16	high_impact	3,94	neutral	0,67	damaging	0,04	deleterious	4,72	24,6	0,02	0,35	disease	0,83	disease	0,89	disease	0,77	disease	0,84	7	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,88	low_impact	-2,81	medium_impact	-0,07	high_impact	2,35	0,14	0,8	73,95	11,87	P	0,57	P	0,96	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9940	9940	T	G	MI.8215	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	734	245	V	G	gTa/gGa	9,15	1	0	probably_damaging	1	neutral	0,31	neutral	1,56	deleterious	-7,59	deleterious	-6,02	high_impact	4,09	damaging	0,57	damaging	0,05	deleterious	3,96	23,6	0,02	0,35	disease	0,83	disease	0,84	disease	0,71	disease	0,78	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	-0,01	high_impact	2,48	0,15	0,8	73,95	11,87	N	0,48	N	0,88	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9942	9942	G	A	MI.8216	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	736	246	D	N	Gat/Aat	-0,1	0,73	0	probably_damaging	0,99	neutral	0,31	neutral	1,43	deleterious	-5,62	deleterious	-4,3	high_impact	3,96	damaging	0,55	damaging	0,02	deleterious	4,31	24	0,27	0,45	neutral	0,47	disease	0,89	disease	0,67	disease	0,74	5	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,82	low_impact	-2,81	medium_impact	-0,01	high_impact	2,37	0,8	0,85	73,56	12,71	N	0,35	N	0,96	polymorphism	1	0,47	rs28715301	.	.	.	.	endometrial tumor	.	.	.	.	.	.	.	.	.
chrM	9942	9942	G	C	MI.8217	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	736	246	D	H	Gat/Cat	-0,1	0,73	0	probably_damaging	1	neutral	0,56	neutral	1,41	deleterious	-7,09	deleterious	-6,02	high_impact	4,66	damaging	0,58	damaging	0,01	deleterious	3,76	23,3	0,05	0,35	disease	0,7	disease	0,89	disease	0,79	disease	0,82	6	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	0,25	high_impact	2,99	0,33	0,8	73,56	12,71	N	0,51	P	0,99	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9942	9942	G	T	MI.8218	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	736	246	D	Y	Gat/Tat	-0,1	0,73	0	probably_damaging	1	neutral	1	neutral	1,41	deleterious	-7,57	deleterious	-7,74	high_impact	4,66	neutral	0,6	damaging	0,01	deleterious	4,05	23,7	0,03	0,35	disease	0,81	disease	0,96	disease	0,72	disease	0,85	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,89	low_impact	-3,78	high_impact	1,9	high_impact	2,99	0,15	0,8	73,56	12,71	N	0,43	N	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9943	9943	A	C	MI.8219	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	737	246	D	A	gAt/gCt	7,3	1	0	probably_damaging	1	neutral	0,51	neutral	1,44	deleterious	-5,48	deleterious	-6,88	high_impact	4,66	damaging	0,6	damaging	0,02	deleterious	3,81	23,4	0,05	0,35	disease	0,53	disease	0,9	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	0,2	high_impact	2,99	0,3	0,8	73,56	12,71	P	0,55	P	0,83	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8912	8912	T	G	MI.822	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	386	129	L	W	tTa/tGa	-0,33	0	0	probably_damaging	1	neutral	0,09	neutral	4,07	neutral	-2,73	deleterious	-5,54	high_impact	4,14	neutral	0,78	damaging	0,13	deleterious	3,82	23,4	0,17	0,65	disease	0,92	disease	0,71	disease	0,72	disease	0,79	6	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,86	low_impact	-3,6	medium_impact	-0,28	high_impact	2,45	0,55	0,9	49,12	8,65	N	0,29	N	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9943	9943	A	G	MI.8220	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	737	246	D	G	gAt/gGt	7,3	1	0	probably_damaging	1	neutral	0,33	neutral	1,43	deleterious	-5,87	deleterious	-6,02	high_impact	4,11	damaging	0,58	damaging	0,01	deleterious	4,04	23,7	0,06	0,35	disease	0,59	disease	0,89	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	0,02	high_impact	2,5	0,24	0,8	73,56	12,71	N	0,48	N	0,97	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9943	9943	A	T	MI.8221	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	737	246	D	V	gAt/gTt	7,3	1	0	probably_damaging	1	neutral	0,68	neutral	1,43	deleterious	-5,91	deleterious	-7,74	high_impact	4,3	damaging	0,56	damaging	0,01	deleterious	3,8	23,4	0,03	0,35	disease	0,72	disease	0,94	disease	0,73	disease	0,86	7	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,86	low_impact	-3,78	medium_impact	0,38	high_impact	2,67	0,11	0,8	73,56	12,71	N	0,49	N	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9944	9944	T	A	MI.8222	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	738	246	D	E	gaT/gaA	6,84	1	0	probably_damaging	0,97	neutral	0,29	neutral	1,6	deleterious	-3,06	deleterious	-3,44	high_impact	4,11	neutral	0,62	damaging	0,02	deleterious	4,18	23,8	0,17	0,45	neutral	0,28	disease	0,85	disease	0,67	disease	0,74	5	neutral	0,98	neutral	0,16	deleterious	2	deleterious	0,76	low_impact	-2,34	medium_impact	-0,03	high_impact	2,5	0,44	0,8	73,56	12,71	P	0,55	P	0,93	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9944	9944	T	G	MI.8223	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	738	246	D	E	gaT/gaG	6,84	1	0	probably_damaging	0,97	neutral	0,29	neutral	1,6	deleterious	-3,06	deleterious	-3,44	high_impact	4,11	neutral	0,62	damaging	0,02	deleterious	4	23,6	0,17	0,45	neutral	0,28	disease	0,85	disease	0,67	disease	0,74	5	neutral	0,98	neutral	0,16	deleterious	2	deleterious	0,76	low_impact	-2,34	medium_impact	-0,03	high_impact	2,5	0,44	0,8	73,56	12,71	P	0,53	P	0,93	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9945	9945	G	C	MI.8224	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	739	247	V	L	Gtg/Ctg	-1,72	0	0	possibly_damaging	0,85	neutral	0,37	neutral	1,8	neutral	-2,08	neutral	-2,3	medium_impact	3	damaging	0,57	damaging	0,03	neutral	1,75	14,71	0,25	0,45	neutral	0,24	disease	0,84	neutral	0,47	disease	0,67	3	neutral	0,86	neutral	0,26	NA	0	deleterious	0,61	low_impact	-1,6	medium_impact	0,06	medium_impact	1,51	0,3	0,8	72,8	11,58	N	0,25	N	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9945	9945	G	T	MI.8225	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	739	247	V	L	Gtg/Ttg	-1,72	0	0	possibly_damaging	0,85	neutral	0,37	neutral	1,8	neutral	-2,08	neutral	-2,3	medium_impact	3	damaging	0,57	damaging	0,03	deleterious	1,88	15,48	0,25	0,45	neutral	0,24	disease	0,84	neutral	0,47	disease	0,67	3	neutral	0,86	neutral	0,26	NA	0	deleterious	0,61	low_impact	-1,6	medium_impact	0,06	medium_impact	1,51	0,3	0,8	72,8	11,58	N	0,25	N	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9945	9945	G	A	MI.8226	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	739	247	V	M	Gtg/Atg	-1,72	0	0	probably_damaging	0,99	neutral	0,06	neutral	1,64	deleterious	-4,27	neutral	-2,29	high_impact	3,52	neutral	0,61	damaging	0,04	deleterious	3,59	23,2	0,17	0,45	disease	0,57	disease	0,75	disease	0,54	disease	0,59	2	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,76	low_impact	-2,81	medium_impact	-0,49	medium_impact	1,97	0,55	0,8	72,8	11,58	N	0,27	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9946	9946	T	G	MI.8227	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	740	247	V	G	gTg/gGg	4,29	1	0	probably_damaging	0,99	deleterious	0,02	neutral	1,61	deleterious	-5,68	deleterious	-5,9	medium_impact	3,11	damaging	0,57	damaging	0,05	deleterious	3,84	23,4	0,03	0,35	disease	0,82	disease	0,86	disease	0,59	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,83	low_impact	-2,81	medium_impact	-0,77	medium_impact	1,61	0,21	0,8	72,8	11,58	N	0,32	N	0,88	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9946	9946	T	C	MI.8228	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	740	247	V	A	gTg/gCg	4,29	1	0	probably_damaging	0,98	deleterious	0,04	neutral	1,66	deleterious	-3,8	deleterious	-3,35	medium_impact	3,35	damaging	0,59	damaging	0,04	deleterious	2,11	16,94	0,13	0,4	disease	0,55	disease	0,79	disease	0,58	disease	0,69	4	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,78	low_impact	-2,51	medium_impact	-0,6	medium_impact	1,82	0,09	0,8	72,8	11,58	N	0,38	N	0,39	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9946	9946	T	A	MI.8229	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	740	247	V	E	gTg/gAg	4,29	1	0	probably_damaging	0,99	deleterious	0,01	neutral	1,62	deleterious	-5,46	deleterious	-5,04	high_impact	4,5	neutral	0,65	damaging	0,03	deleterious	4,54	24,3	0,02	0,35	disease	0,82	disease	0,91	disease	0,68	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,81	medium_impact	-0,95	high_impact	2,85	0,13	0,8	72,8	11,58	N	0,46	N	0,96	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8912	8912	T	C	MI.823	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	386	129	L	S	tTa/tCa	-0,33	0	0	probably_damaging	1	neutral	0,13	neutral	4,11	neutral	-2,32	deleterious	-5,5	high_impact	3,8	neutral	0,88	damaging	0,17	deleterious	3,79	23,4	0,26	0,65	disease	0,72	disease	0,74	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,83	low_impact	-3,6	medium_impact	-0,18	high_impact	2,16	0,68	0,9	49,12	8,65	N	0,35	N	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9948	9948	G	C	MI.8230	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	742	248	V	L	Gtt/Ctt	-9,59	0	0,01	benign	0,06	neutral	0,52	neutral	1,69	deleterious	-3,19	deleterious	-2,54	high_impact	4,56	neutral	0,63	neutral	0,56	deleterious	1,86	15,33	0,1	0,4	neutral	0,26	disease	0,86	disease	0,63	disease	0,74	5	neutral	0,42	deleterious	0,73	neutral	-2	neutral	0,25	medium_impact	0,29	medium_impact	0,21	high_impact	2,9	0,27	0,8	75,1	10,79	N	0,47	N	0,71	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9948	9948	G	A	MI.8231	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	742	248	V	I	Gtt/Att	-9,59	0	0,01	benign	0,01	neutral	0,31	neutral	1,93	neutral	-2,26	neutral	-0,84	low_impact	1,73	neutral	0,61	neutral	0,64	deleterious	0,74	9,11	0,21	0,45	neutral	0,2	disease	0,61	disease	0,57	neutral	0,43	1	neutral	0,68	deleterious	0,65	neutral	-6	neutral	0,19	medium_impact	1,07	medium_impact	-0,01	medium_impact	0,37	0,51	0,8	75,1	10,79	N	0,38	N	0,06	polymorphism	1	0,03	.	.	.	.	.	papillary thyroid carcinoma	.	.	.	.	.	.	.	.	.
chrM	9948	9948	G	T	MI.8232	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	742	248	V	F	Gtt/Ttt	-9,59	0	0,01	possibly_damaging	0,78	neutral	0,4	neutral	1,59	deleterious	-6,22	deleterious	-4,25	high_impact	4,56	damaging	0,58	neutral	0,51	deleterious	3,92	23,5	0,03	0,35	disease	0,51	disease	0,94	disease	0,69	disease	0,82	6	neutral	0,79	neutral	0,31	deleterious	1	deleterious	0,74	low_impact	-1,4	medium_impact	0,09	high_impact	2,9	0,17	0,8	75,1	10,79	N	0,45	N	0,97	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9949	9949	T	C	MI.8233	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	743	248	V	A	gTt/gCt	4,29	1	0	possibly_damaging	0,54	neutral	0,22	neutral	1,66	deleterious	-5,34	deleterious	-3,4	high_impact	4,01	neutral	0,63	neutral	0,7	deleterious	3,6	23,2	0,05	0,35	neutral	0,43	disease	0,78	disease	0,67	disease	0,71	4	neutral	0,77	neutral	0,34	deleterious	1	deleterious	0,49	medium_impact	-0,94	medium_impact	-0,12	high_impact	2,41	0,11	0,8	75,1	10,79	P	0,52	P	0,82	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9949	9949	T	A	MI.8234	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	743	248	V	D	gTt/gAt	4,29	1	0	possibly_damaging	0,9	neutral	0,18	neutral	1,57	deleterious	-8,62	deleterious	-5,95	high_impact	4,56	neutral	0,61	neutral	0,5	deleterious	4,57	24,4	0,02	0,35	disease	0,8	disease	0,91	disease	0,76	disease	0,84	7	neutral	0,94	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-1,8	medium_impact	-0,18	high_impact	2,9	0,09	0,8	75,1	10,79	P	0,53	P	0,97	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9949	9949	T	G	MI.8235	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	743	248	V	G	gTt/gGt	4,29	1	0	possibly_damaging	0,9	neutral	0,21	neutral	1,58	deleterious	-7,84	deleterious	-5,96	high_impact	4,56	neutral	0,61	neutral	0,66	deleterious	3,96	23,6	0,03	0,35	disease	0,7	disease	0,85	disease	0,69	disease	0,75	5	neutral	0,93	neutral	0,16	deleterious	1	deleterious	0,79	low_impact	-1,8	medium_impact	-0,14	high_impact	2,9	0,13	0,8	75,1	10,79	N	0,5	N	0,96	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9951	9951	T	C	MI.8236	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	745	249	W	R	Tga/Cga	-13,29	0	0	probably_damaging	1	neutral	0,05	neutral	-1,2	deleterious	-11,85	deleterious	-12,02	high_impact	3,98	damaging	0,48	damaging	0,16	deleterious	3,69	23,3	0,04	0,35	neutral	0,38	disease	0,89	disease	0,76	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,54	high_impact	2,38	0,09	0,8	74,33	11,7	N	0,41	N	0,99	polymorphism	1	0,46	rs879091798	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9951	9951	T	G	MI.8237	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	745	249	W	G	Tga/Gga	-13,29	0	0	probably_damaging	1	neutral	0,05	neutral	-1,21	deleterious	-12,4	deleterious	-11,16	high_impact	3,98	damaging	0,6	neutral	0,37	deleterious	4,01	23,6	0,04	0,35	disease	0,71	disease	0,83	disease	0,73	disease	0,77	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,54	high_impact	2,38	0,05	0,8	74,33	11,7	N	0,36	N	0,98	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9952	9952	G	T	MI.8238	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	746	249	W	L	tGa/tTa	7,3	1	0	probably_damaging	1	neutral	1	neutral	-1,2	deleterious	-10,54	deleterious	-11,15	high_impact	4,33	damaging	0,57	neutral	0,37	deleterious	4,36	24,1	0,04	0,35	neutral	0,31	disease	0,88	disease	0,72	disease	0,78	6	deleterious	0,99	deleterious	0,5	deleterious	2	deleterious	0,78	low_impact	-3,78	high_impact	1,9	high_impact	2,7	0,05	0,8	74,33	11,7	N	0,42	N	1	polymorphism	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9952	9952	G	C	MI.8239	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	746	249	W	S	tGa/tCa	7,3	1	0	probably_damaging	1	neutral	0,06	neutral	-1,21	deleterious	-12,47	deleterious	-12,01	high_impact	4,67	neutral	0,63	neutral	0,36	deleterious	4,09	23,7	0,04	0,35	disease	0,59	disease	0,88	disease	0,72	disease	0,78	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,83	low_impact	-3,78	medium_impact	-0,49	high_impact	3	0,05	0,8	74,33	11,7	N	0,42	N	0,97	disease_causing	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8913	8913	A	T	MI.824	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	387	129	L	F	ttA/ttT	7,53	0,96	0	probably_damaging	1	deleterious	0	neutral	4,13	neutral	-1,33	deleterious	-3,67	high_impact	3,6	neutral	0,88	damaging	0,15	deleterious	3,61	23,2	0,41	0,65	disease	0,75	disease	0,67	disease	0,69	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,6	low_impact	-1,4	medium_impact	1,99	0,58	0,9	49,12	8,65	P	0,54	P	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9953	9953	A	C	MI.8240	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	747	249	W	C	tgA/tgC	7,3	1	0	probably_damaging	1	deleterious	0,03	neutral	-1,21	deleterious	-14,66	deleterious	-11,15	high_impact	4,67	damaging	0,58	damaging	0,17	deleterious	4,12	23,8	0,04	0,35	disease	0,82	disease	0,9	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,85	low_impact	-3,78	medium_impact	-0,67	high_impact	3	0,06	0,8	74,33	11,7	N	0,43	N	1	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9953	9953	A	T	MI.8241	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	747	249	W	C	tgA/tgT	7,3	1	0	probably_damaging	1	deleterious	0,03	neutral	-1,21	deleterious	-14,66	deleterious	-11,15	high_impact	4,67	damaging	0,58	damaging	0,17	deleterious	4,23	23,9	0,04	0,35	disease	0,82	disease	0,9	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,85	low_impact	-3,78	medium_impact	-0,67	high_impact	3	0,06	0,8	74,33	11,7	N	0,43	N	1	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9954	9954	C	G	MI.8242	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	748	250	L	V	Cta/Gta	3,14	0,99	0	probably_damaging	0,91	neutral	0,43	neutral	2,19	neutral	-0,52	neutral	-2,14	low_impact	1,73	damaging	0,54	damaging	0,04	deleterious	3,55	23,1	0,15	0,4	neutral	0,21	disease	0,68	neutral	0,45	neutral	0,49	0	neutral	0,91	neutral	0,26	neutral	-2	deleterious	0,64	low_impact	-1,85	medium_impact	0,12	medium_impact	0,37	0,53	0,8	73,95	11,7	N	0,34	N	0,81	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9954	9954	C	A	MI.8243	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	748	250	L	M	Cta/Ata	3,14	0,99	0	probably_damaging	0,99	neutral	0,09	neutral	1,97	deleterious	-3,96	neutral	-1,56	high_impact	3,54	neutral	0,61	damaging	0,04	deleterious	3,83	23,4	0,12	0,4	neutral	0,46	disease	0,54	disease	0,54	disease	0,62	2	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,71	low_impact	-2,81	medium_impact	-0,38	medium_impact	1,99	0,5	0,8	73,95	11,7	N	0,42	N	0,85	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9955	9955	T	A	MI.8244	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	749	250	L	Q	cTa/cAa	-0,57	0,13	0	probably_damaging	0,99	neutral	0,09	neutral	1,94	deleterious	-5,7	deleterious	-4,99	high_impact	4,23	neutral	0,62	damaging	0,02	deleterious	4,38	24,1	0,03	0,35	disease	0,58	disease	0,75	disease	0,57	disease	0,67	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,76	low_impact	-2,81	medium_impact	-0,38	high_impact	2,61	0,3	0,8	73,95	11,7	N	0,35	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9955	9955	T	G	MI.8245	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	749	250	L	R	cTa/cGa	-0,57	0,13	0	probably_damaging	0,99	deleterious	0,03	neutral	1,94	deleterious	-6,08	deleterious	-5	high_impact	4,23	neutral	0,68	damaging	0,02	deleterious	4,29	24	0,02	0,35	disease	0,73	disease	0,89	disease	0,68	disease	0,75	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-2,81	medium_impact	-0,67	high_impact	2,61	0,12	0,8	73,95	11,7	N	0,33	N	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9955	9955	T	C	MI.8246	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	749	250	L	P	cTa/cCa	-0,57	0,13	0	probably_damaging	1	deleterious	0,02	neutral	1,95	deleterious	-6,45	deleterious	-5,75	high_impact	3,88	damaging	0,57	damaging	0,03	deleterious	4,1	23,7	0,02	0,35	disease	0,79	disease	0,8	disease	0,68	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,78	medium_impact	-0,77	high_impact	2,3	0,35	0,8	73,95	11,7	N	0,33	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9957	9957	T	C	MI.8247	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	751	251	F	L	Ttt/Ctt	-4,5	0	0	benign	0	neutral	0,9	neutral	1,92	neutral	-2,01	deleterious	-4,7	medium_impact	2,51	damaging	0,51	neutral	0,7	deleterious	2,06	16,61	0,13	0,4	neutral	0,21	disease	0,78	disease	0,58	disease	0,52	0	neutral	0,09	deleterious	0,95	neutral	-3	neutral	0,17	high_impact	2,05	medium_impact	0,74	medium_impact	1,07	0,34	0,8	62,07	11,69	N	0,46	N	0,41	polymorphism	1	0,11	.	.	.	.	.	.	.	CPD	3,56	T9957C	PEM/MELAS/NAION	-	+	Reported	6
chrM	9957	9957	T	A	MI.8248	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	751	251	F	I	Ttt/Att	-4,5	0	0	benign	0,01	neutral	0,08	neutral	1,86	neutral	-2,74	deleterious	-4,76	medium_impact	2,54	neutral	0,63	neutral	0,62	deleterious	2,56	19,87	0,15	0,4	neutral	0,28	disease	0,85	disease	0,59	disease	0,69	4	neutral	0,92	deleterious	0,54	neutral	-3	neutral	0,23	medium_impact	1,07	medium_impact	-0,41	medium_impact	1,09	0,3	0,8	62,07	11,69	N	0,42	N	0,78	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9957	9957	T	G	MI.8249	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	751	251	F	V	Ttt/Gtt	-4,5	0	0	benign	0,04	neutral	0,21	neutral	1,87	neutral	-2,6	deleterious	-5,61	medium_impact	2,64	neutral	0,67	neutral	0,56	deleterious	2,23	17,69	0,11	0,4	neutral	0,21	disease	0,87	disease	0,63	disease	0,73	5	neutral	0,78	deleterious	0,59	neutral	-3	neutral	0,19	medium_impact	0,47	medium_impact	-0,14	medium_impact	1,18	0,27	0,8	62,07	11,69	N	0,37	N	0,9	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8913	8913	A	C	MI.825	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	387	129	L	F	ttA/ttC	7,53	0,96	0	probably_damaging	1	deleterious	0	neutral	4,13	neutral	-1,33	deleterious	-3,67	high_impact	3,6	neutral	0,88	damaging	0,15	deleterious	3,48	23,1	0,41	0,65	disease	0,75	disease	0,67	disease	0,69	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,6	low_impact	-1,4	medium_impact	1,99	0,58	0,9	49,12	8,65	P	0,54	P	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9958	9958	T	A	MI.8250	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	752	251	F	Y	tTt/tAt	4,52	1	0	benign	0,08	neutral	0,54	neutral	1,84	deleterious	-3,03	neutral	-2,47	high_impact	3,73	neutral	0,74	neutral	0,41	deleterious	2,68	20,7	0,2	0,45	neutral	0,3	disease	0,83	disease	0,65	disease	0,72	4	neutral	0,39	deleterious	0,73	neutral	-2	neutral	0,26	medium_impact	0,16	medium_impact	0,23	high_impact	2,16	0,39	0,8	62,07	11,69	N	0,52	P	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9958	9958	T	C	MI.8251	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	752	251	F	S	tTt/tCt	4,52	1	0	benign	0,17	neutral	0,21	neutral	1,82	deleterious	-3,57	deleterious	-6,54	high_impact	4,08	neutral	0,83	neutral	0,59	deleterious	2,81	21,4	0,07	0,35	neutral	0,4	disease	0,82	disease	0,63	disease	0,71	4	neutral	0,75	deleterious	0,52	neutral	-2	neutral	0,41	medium_impact	-0,2	medium_impact	-0,14	high_impact	2,47	0,2	0,8	62,07	11,69	P	0,55	P	0,97	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9958	9958	T	G	MI.8252	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	752	251	F	C	tTt/tGt	4,52	1	0	possibly_damaging	0,62	deleterious	0,01	neutral	1,78	deleterious	-5,42	deleterious	-6,43	medium_impact	2,98	neutral	0,74	neutral	0,45	deleterious	4,17	23,8	0,08	0,35	disease	0,62	disease	0,86	disease	0,61	disease	0,68	4	deleterious	0,99	neutral	0,2	deleterious	4	deleterious	0,65	low_impact	-1,08	medium_impact	-0,95	medium_impact	1,49	0,12	0,8	62,07	11,69	N	0,39	N	0,95	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9959	9959	T	A	MI.8253	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	753	251	F	L	ttT/ttA	5,68	1	0	benign	0	neutral	0,9	neutral	1,92	neutral	-2,01	deleterious	-4,7	medium_impact	2,51	damaging	0,51	neutral	0,7	deleterious	2,63	20,4	0,13	0,4	neutral	0,21	disease	0,78	disease	0,58	disease	0,52	0	neutral	0,09	deleterious	0,95	neutral	-3	neutral	0,17	high_impact	2,05	medium_impact	0,74	medium_impact	1,07	0,34	0,8	62,07	11,69	P	0,57	P	0,41	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9959	9959	T	G	MI.8254	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	753	251	F	L	ttT/ttG	5,68	1	0	benign	0	neutral	0,9	neutral	1,92	neutral	-2,01	deleterious	-4,7	medium_impact	2,51	damaging	0,51	neutral	0,7	deleterious	2,5	19,46	0,13	0,4	neutral	0,21	disease	0,78	disease	0,58	disease	0,52	0	neutral	0,09	deleterious	0,95	neutral	-3	neutral	0,17	high_impact	2,05	medium_impact	0,74	medium_impact	1,07	0,34	0,8	62,07	11,69	P	0,56	P	0,41	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9960	9960	C	A	MI.8255	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	754	252	L	M	Ctg/Atg	2,9	1	0	probably_damaging	1	deleterious	0,03	neutral	1,7	deleterious	-4,07	neutral	-1,72	high_impact	4,04	damaging	0,58	damaging	0,04	deleterious	3,9	23,5	0,12	0,4	neutral	0,46	disease	0,61	disease	0,54	disease	0,63	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,72	low_impact	-3,78	medium_impact	-0,67	high_impact	2,44	0,45	0,8	74,71	11,64	N	0,38	N	0,85	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9960	9960	C	G	MI.8256	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	754	252	L	V	Ctg/Gtg	2,9	1	0	probably_damaging	0,95	neutral	0,22	neutral	1,92	neutral	-2,04	deleterious	-2,58	medium_impact	2,41	damaging	0,48	damaging	0,05	deleterious	3,58	23,2	0,15	0,45	neutral	0,19	disease	0,72	disease	0,54	disease	0,51	0	neutral	0,97	neutral	0,14	deleterious	1	deleterious	0,67	low_impact	-2,11	medium_impact	-0,12	medium_impact	0,98	0,42	0,8	74,71	11,64	N	0,38	N	0,81	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9961	9961	T	G	MI.8257	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	755	252	L	R	cTg/cGg	0,13	0,98	0	probably_damaging	1	deleterious	0,04	neutral	1,62	deleterious	-8,17	deleterious	-5,15	high_impact	4,59	neutral	0,68	damaging	0,02	deleterious	4,27	23,9	0,03	0,35	disease	0,65	disease	0,91	disease	0,74	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,85	low_impact	-3,78	medium_impact	-0,6	high_impact	2,93	0,17	0,8	74,71	11,64	N	0,49	N	0,99	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9961	9961	T	A	MI.8258	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	755	252	L	Q	cTg/cAg	0,13	0,98	0	probably_damaging	1	deleterious	0,03	neutral	1,62	deleterious	-8,29	deleterious	-5,14	high_impact	4,59	damaging	0,6	damaging	0,03	deleterious	4,15	23,8	0,03	0,35	disease	0,66	disease	0,81	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,8	low_impact	-3,78	medium_impact	-0,67	high_impact	2,93	0,23	0,8	74,71	11,64	N	0,44	N	0,97	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9961	9961	T	C	MI.8259	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	755	252	L	P	cTg/cCg	0,13	0,98	0	probably_damaging	1	deleterious	0,02	neutral	1,62	deleterious	-7,76	deleterious	-6	high_impact	4,04	damaging	0,48	damaging	0,03	deleterious	3,95	23,6	0,02	0,35	disease	0,59	disease	0,83	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,84	low_impact	-3,78	medium_impact	-0,77	high_impact	2,44	0,22	0,8	74,71	11,64	N	0,38	N	0,99	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8914	8914	C	A	MI.826	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	388	130	P	T	Cca/Aca	-6,81	0	0	probably_damaging	1	deleterious	0,04	neutral	3,42	deleterious	-3,05	deleterious	-7,29	high_impact	3,53	damaging	0,59	damaging	0,07	deleterious	3,71	23,3	0,44	0,65	disease	0,71	disease	0,8	disease	0,71	disease	0,7	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,85	low_impact	-3,6	medium_impact	-0,49	medium_impact	1,93	0,68	0,9	49,12	8,75	N	0,26	N	0,93	disease_causing	0,74	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9963	9963	T	A	MI.8260	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	757	253	Y	N	Tat/Aat	-14,91	0	0	probably_damaging	1	neutral	0,07	neutral	1,71	deleterious	-5,14	deleterious	-6,86	high_impact	3,93	neutral	0,62	neutral	0,37	deleterious	4,13	23,8	0,06	0,35	neutral	0,39	disease	0,87	disease	0,65	disease	0,75	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	-0,45	high_impact	2,34	0,11	0,8	74,71	12,44	N	0,34	N	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9963	9963	T	C	MI.8261	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	757	253	Y	H	Tat/Cat	-14,91	0	0	probably_damaging	1	neutral	0,22	neutral	1,74	deleterious	-4,08	deleterious	-4	high_impact	3,93	neutral	0,67	neutral	0,39	deleterious	3,64	23,2	0,08	0,35	neutral	0,48	disease	0,81	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,76	low_impact	-3,78	medium_impact	-0,12	high_impact	2,34	0,17	0,8	74,71	12,44	N	0,39	N	0,97	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9963	9963	T	G	MI.8262	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	757	253	Y	D	Tat/Gat	-14,91	0	0	probably_damaging	1	neutral	0,14	neutral	1,7	deleterious	-6,15	deleterious	-7,42	high_impact	3,93	neutral	0,66	neutral	0,4	deleterious	4,06	23,7	0,03	0,35	neutral	0,43	disease	0,88	disease	0,74	disease	0,8	6	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,77	low_impact	-3,78	medium_impact	-0,26	high_impact	2,34	0,15	0,8	74,71	12,44	N	0,4	N	0,99	disease_causing	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9964	9964	A	C	MI.8263	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	758	253	Y	S	tAt/tCt	5,68	1	0	probably_damaging	1	neutral	0,28	neutral	1,72	deleterious	-4,75	deleterious	-6,56	medium_impact	3,24	neutral	0,71	neutral	0,5	deleterious	3,99	23,6	0,06	0,35	neutral	0,29	disease	0,84	disease	0,63	disease	0,73	5	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,74	low_impact	-3,78	medium_impact	-0,04	medium_impact	1,72	0,13	0,8	74,71	12,44	N	0,46	N	0,96	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9964	9964	A	T	MI.8264	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	758	253	Y	F	tAt/tTt	5,68	1	0	probably_damaging	0,99	neutral	0,62	neutral	2,13	neutral	-0,61	neutral	-1,41	neutral_impact	0,09	damaging	0,57	neutral	0,75	deleterious	2,42	18,94	0,18	0,45	neutral	0,12	neutral	0,29	neutral	0,42	neutral	0,38	2	deleterious	0,99	neutral	0,32	neutral	-2	deleterious	0,68	low_impact	-2,81	medium_impact	0,31	low_impact	-1,1	0,34	0,8	74,71	12,44	P	0,51	P	0,72	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9964	9964	A	G	MI.8265	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	758	253	Y	C	tAt/tGt	5,68	1	0	probably_damaging	1	neutral	0,13	neutral	1,7	deleterious	-6,31	deleterious	-6,56	high_impact	3,58	neutral	0,61	damaging	0,25	deleterious	3,71	23,3	0,06	0,35	disease	0,58	disease	0,9	disease	0,69	disease	0,77	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,78	low_impact	-3,78	medium_impact	-0,28	high_impact	2,03	0,12	0,8	74,71	12,44	N	0,43	N	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9966	9966	G	A	MI.8266	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	760	254	V	I	Gtc/Atc	-4,73	0	0,03	benign	0	neutral	0,59	neutral	2,22	neutral	-0,48	neutral	0,19	neutral_impact	-0,12	neutral	0,92	neutral	0,96	neutral	-0,85	0,03	0,34	0,5	neutral	0,18	neutral	0,09	neutral	0,19	neutral	0,26	5	neutral	0,41	deleterious	0,8	neutral	-6	neutral	0,07	high_impact	2,05	medium_impact	0,28	low_impact	-1,29	0,73	0,85	NA	NA	N	0,4	N	0,06	polymorphism	1	0,01	rs200809063	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9966	9966	G	T	MI.8267	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	760	254	V	F	Gtc/Ttc	-4,73	0	0,03	benign	0,13	neutral	0,48	neutral	1,97	deleterious	-3,18	deleterious	-2,83	low_impact	1,63	neutral	0,63	neutral	0,45	deleterious	1,99	16,16	0,05	0,35	neutral	0,29	disease	0,79	neutral	0,44	disease	0,55	1	neutral	0,43	deleterious	0,68	neutral	-6	neutral	0,27	medium_impact	-0,07	medium_impact	0,17	medium_impact	0,28	0,33	0,8	NA	NA	N	0,34	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9966	9966	G	C	MI.8268	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	760	254	V	L	Gtc/Ctc	-4,73	0	0,03	benign	0	neutral	0,54	neutral	2,14	neutral	-0,93	neutral	-1,12	neutral_impact	0,07	neutral	0,75	neutral	0,79	deleterious	0,55	7,8	0,19	0,45	neutral	0,18	neutral	0,47	neutral	0,26	neutral	0,46	1	neutral	0,46	deleterious	0,77	neutral	-6	neutral	0,12	high_impact	2,05	medium_impact	0,23	low_impact	-1,12	0,54	0,8	NA	NA	N	0,37	N	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9967	9967	T	C	MI.8269	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	761	254	V	A	gTc/gCc	0,36	0,13	0	benign	0,07	neutral	0,21	neutral	2,01	neutral	-2,38	deleterious	-2,9	low_impact	0,86	neutral	0,7	neutral	0,7	neutral	1,72	14,52	0,13	0,4	neutral	0,2	disease	0,53	neutral	0,45	neutral	0,46	1	neutral	0,77	deleterious	0,57	neutral	-6	neutral	0,16	medium_impact	0,22	medium_impact	-0,14	medium_impact	-0,41	0,28	0,8	NA	NA	N	0,46	N	0,82	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8914	8914	C	T	MI.827	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	388	130	P	S	Cca/Tca	-6,81	0	0	probably_damaging	1	deleterious	0	neutral	3,42	neutral	-2,76	deleterious	-7,29	high_impact	4,63	damaging	0,59	damaging	0,08	deleterious	3,93	23,5	0,48	0,65	disease	0,85	disease	0,78	disease	0,71	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,28	0,9	49,12	8,75	N	0,38	N	0,82	disease_causing	0,75	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9967	9967	T	A	MI.8270	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	761	254	V	D	gTc/gAc	0,36	0,13	0	benign	0,31	neutral	0,15	neutral	1,94	deleterious	-4,88	deleterious	-4,89	medium_impact	3,28	neutral	0,62	neutral	0,34	deleterious	2,92	22	0,02	0,35	disease	0,57	disease	0,82	disease	0,64	disease	0,77	5	neutral	0,82	neutral	0,42	neutral	-3	deleterious	0,54	medium_impact	-0,53	medium_impact	-0,24	medium_impact	1,76	0,08	0,8	NA	NA	N	0,37	N	0,97	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9967	9967	T	G	MI.8271	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	761	254	V	G	gTc/gGc	0,36	0,13	0	benign	0,37	neutral	0,13	neutral	1,95	deleterious	-4,24	deleterious	-5,39	low_impact	1,49	neutral	0,63	neutral	0,53	deleterious	2,3	18,17	0,04	0,35	neutral	0,29	disease	0,67	disease	0,55	disease	0,7	4	neutral	0,85	neutral	0,38	neutral	-6	neutral	0,39	medium_impact	-0,64	medium_impact	-0,28	medium_impact	0,15	0,16	0,8	NA	NA	N	0,41	N	0,96	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9969	9969	T	A	MI.8272	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	763	255	S	T	Tcc/Acc	-12,37	0	0	probably_damaging	0,96	neutral	0,16	neutral	2,58	neutral	0,38	neutral	-2	low_impact	1,32	neutral	0,67	neutral	0,77	deleterious	3,83	23,4	0,4	0,5	neutral	0,19	neutral	0,41	neutral	0,42	neutral	0,44	1	neutral	0,98	neutral	0,1	neutral	-2	deleterious	0,6	low_impact	-2,21	medium_impact	-0,22	medium_impact	0	0,68	0,85	73,56	12,63	N	0,48	N	0,63	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9969	9969	T	C	MI.8273	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	763	255	S	P	Tcc/Ccc	-12,37	0	0	probably_damaging	1	neutral	0,05	neutral	2,51	neutral	-2,23	deleterious	-3,81	medium_impact	3,28	damaging	0,58	neutral	0,46	deleterious	4,07	23,7	0,05	0,35	disease	0,51	disease	0,81	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,8	low_impact	-3,78	medium_impact	-0,54	medium_impact	1,76	0,36	0,8	73,56	12,63	N	0,35	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9969	9969	T	G	MI.8274	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	763	255	S	A	Tcc/Gcc	-12,37	0	0	probably_damaging	0,98	neutral	0,12	neutral	2,58	neutral	0,66	neutral	-2	low_impact	1,92	neutral	0,64	neutral	0,65	deleterious	3,75	23,3	0,38	0,5	neutral	0,22	neutral	0,46	neutral	0,44	neutral	0,45	1	deleterious	0,99	neutral	0,07	neutral	-2	deleterious	0,66	low_impact	-2,51	medium_impact	-0,3	medium_impact	0,54	0,54	0,8	73,56	12,63	N	0,46	N	0,4	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9970	9970	C	T	MI.8275	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	764	255	S	F	tCc/tTc	3,6	1	0	probably_damaging	1	neutral	0,2	neutral	2,67	neutral	1,53	deleterious	-4,26	low_impact	0,84	neutral	0,63	neutral	0,77	deleterious	4,39	24,1	0,08	0,35	neutral	0,23	disease	0,61	neutral	0,5	neutral	0,45	1	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,7	low_impact	-3,78	medium_impact	-0,15	medium_impact	-0,43	0,2	0,8	73,56	12,63	N	0,42	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9970	9970	C	A	MI.8276	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	764	255	S	Y	tCc/tAc	3,6	1	0	probably_damaging	1	neutral	1	neutral	2,53	neutral	-1,18	deleterious	-4,3	high_impact	3,62	neutral	0,63	neutral	0,39	deleterious	4,21	23,9	0,06	0,35	neutral	0,33	disease	0,8	disease	0,57	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,73	low_impact	-3,78	high_impact	1,9	high_impact	2,06	0,3	0,8	73,56	12,63	N	0,36	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9970	9970	C	G	MI.8277	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	764	255	S	C	tCc/tGc	3,6	1	0	probably_damaging	1	neutral	0,06	neutral	2,51	neutral	-1,3	neutral	-2,34	low_impact	1,11	neutral	0,61	neutral	0,75	deleterious	2,59	20,1	0,1	0,4	disease	0,51	disease	0,58	neutral	0,44	neutral	0,49	0	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,72	low_impact	-3,78	medium_impact	-0,49	medium_impact	-0,19	0,41	0,8	73,56	12,63	N	0,45	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9972	9972	A	T	MI.8278	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	766	256	I	F	Atc/Ttc	-12,37	0	0	possibly_damaging	0,64	neutral	0,63	neutral	1,97	neutral	-0,37	deleterious	-3,42	medium_impact	2,46	neutral	0,65	neutral	0,37	deleterious	4,06	23,7	0,13	0,4	neutral	0,28	disease	0,63	disease	0,54	neutral	0,48	0	neutral	0,57	deleterious	0,5	NA	0	deleterious	0,59	low_impact	-1,11	medium_impact	0,32	medium_impact	1,02	0,54	0,8	75,1	12,41	N	0,29	N	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9972	9972	A	G	MI.8279	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	766	256	I	V	Atc/Gtc	-12,37	0	0	benign	0	neutral	0,46	neutral	2,33	neutral	0,34	neutral	-0,71	neutral_impact	0,76	neutral	0,66	neutral	0,78	deleterious	0,41	6,72	0,55	0,6	neutral	0,12	neutral	0,1	neutral	0,35	neutral	0,29	4	neutral	0,54	deleterious	0,73	neutral	-6	neutral	0,08	high_impact	2,05	medium_impact	0,15	medium_impact	-0,5	0,51	0,8	75,1	12,41	N	0,4	N	0,18	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8914	8914	C	G	MI.828	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	388	130	P	A	Cca/Gca	-6,81	0	0	probably_damaging	1	deleterious	0	neutral	3,42	deleterious	-3	deleterious	-7,29	high_impact	4,63	damaging	0,57	damaging	0,1	deleterious	3,09	22,5	0,34	0,65	disease	0,83	disease	0,58	disease	0,72	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,77	0,9	49,12	8,75	N	0,42	N	0,79	disease_causing	0,64	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9972	9972	A	C	MI.8280	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	766	256	I	L	Atc/Ctc	-12,37	0	0	benign	0,08	neutral	0,5	neutral	2,14	neutral	-0,26	neutral	-1,7	medium_impact	2,07	neutral	0,71	neutral	0,48	deleterious	2,28	18,01	0,24	0,45	neutral	0,16	neutral	0,47	neutral	0,47	neutral	0,43	1	neutral	0,44	deleterious	0,71	neutral	-3	neutral	0,14	medium_impact	0,16	medium_impact	0,19	medium_impact	0,67	0,53	0,8	75,1	12,41	N	0,36	N	0,58	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	A9972C	EXIT & APS2 - possible link	-	+	Reported	1
chrM	9973	9973	T	G	MI.8281	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	767	256	I	S	aTc/aGc	6,84	1	0	probably_damaging	0,97	neutral	0,6	neutral	1,94	deleterious	-3,32	deleterious	-5,06	high_impact	4,18	neutral	0,76	neutral	0,47	deleterious	4,62	24,5	0,02	0,35	neutral	0,46	disease	0,69	disease	0,6	disease	0,66	3	neutral	0,97	neutral	0,32	deleterious	2	deleterious	0,7	low_impact	-2,34	medium_impact	0,29	high_impact	2,56	0,17	0,8	75,1	12,41	N	0,49	N	0,96	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9973	9973	T	C	MI.8282	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	767	256	I	T	aTc/aCc	6,84	1	0	probably_damaging	0,9	neutral	0,3	neutral	1,96	neutral	-2,86	deleterious	-4,14	high_impact	3,84	neutral	0,71	neutral	0,48	deleterious	3,7	23,3	0,05	0,35	neutral	0,39	disease	0,53	disease	0,59	disease	0,65	3	neutral	0,92	neutral	0,2	deleterious	2	deleterious	0,59	low_impact	-1,8	medium_impact	-0,02	high_impact	2,26	0,23	0,8	75,1	12,41	P	0,56	P	0,97	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9973	9973	T	A	MI.8283	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	767	256	I	N	aTc/aAc	6,84	1	0	probably_damaging	0,99	neutral	0,24	neutral	1,92	deleterious	-4,55	deleterious	-5,92	high_impact	3,84	neutral	0,66	neutral	0,34	deleterious	4,73	24,6	0,07	0,35	disease	0,64	disease	0,74	disease	0,63	disease	0,68	4	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,76	low_impact	-2,81	medium_impact	-0,09	high_impact	2,26	0,28	0,8	75,1	12,41	P	0,52	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9974	9974	C	A	MI.8284	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	768	256	I	M	atC/atA	5,68	1	0	possibly_damaging	0,8	neutral	0,24	neutral	1,99	neutral	-2,69	neutral	-2,49	medium_impact	2,73	neutral	0,64	neutral	0,77	deleterious	2,38	18,66	0,17	0,45	neutral	0,37	neutral	0,27	disease	0,53	neutral	0,45	1	neutral	0,86	neutral	0,22	NA	0	neutral	0,4	low_impact	-1,45	medium_impact	-0,09	medium_impact	1,26	0,52	0,8	75,1	12,41	P	0,59	P	0,82	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9974	9974	C	G	MI.8285	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	768	256	I	M	atC/atG	5,68	1	0	possibly_damaging	0,8	neutral	0,24	neutral	1,99	neutral	-2,69	neutral	-2,49	medium_impact	2,73	neutral	0,64	neutral	0,77	deleterious	1,94	15,81	0,17	0,45	neutral	0,37	neutral	0,27	disease	0,53	neutral	0,45	1	neutral	0,86	neutral	0,22	NA	0	neutral	0,4	low_impact	-1,45	medium_impact	-0,09	medium_impact	1,26	0,52	0,8	75,1	12,41	P	0,59	P	0,82	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9975	9975	T	A	MI.8286	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	769	257	Y	N	Tat/Aat	-3,57	0	0	probably_damaging	1	neutral	0,09	neutral	0,63	deleterious	-8,63	deleterious	-7,68	high_impact	4,7	damaging	0,6	damaging	0,02	deleterious	4,32	24	0,04	0,35	disease	0,77	disease	0,67	disease	0,76	disease	0,77	5	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,38	high_impact	3,03	0,09	0,8	72,8	13,53	N	0,44	N	1	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9975	9975	T	G	MI.8287	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	769	257	Y	D	Tat/Gat	-3,57	0	0	probably_damaging	1	neutral	0,06	neutral	0,62	deleterious	-9,55	deleterious	-8,54	high_impact	4,7	neutral	0,64	damaging	0,02	deleterious	4,26	23,9	0,02	0,35	disease	0,79	disease	0,66	disease	0,82	disease	0,76	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	-0,49	high_impact	3,03	0,13	0,8	72,8	13,53	N	0,44	N	0,99	disease_causing	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9975	9975	T	C	MI.8288	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	769	257	Y	H	Tat/Cat	-3,57	0	0	probably_damaging	1	neutral	0,24	neutral	0,65	deleterious	-6,99	deleterious	-4,27	high_impact	4,35	damaging	0,57	damaging	0,02	deleterious	3,86	23,5	0,06	0,35	disease	0,73	disease	0,56	disease	0,81	disease	0,76	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,79	low_impact	-3,78	medium_impact	-0,09	high_impact	2,72	0,14	0,8	72,8	13,53	N	0,42	N	0,97	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9976	9976	A	C	MI.8289	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	770	257	Y	S	tAt/tCt	5,68	1	0	probably_damaging	1	neutral	0,32	neutral	0,63	deleterious	-8,58	deleterious	-7,68	high_impact	4,7	neutral	0,63	damaging	0,04	deleterious	4,05	23,7	0,03	0,35	disease	0,69	disease	0,61	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,8	low_impact	-3,78	medium_impact	0,01	high_impact	3,03	0,11	0,8	72,8	13,53	P	0,58	P	0,96	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8915	8915	C	A	MI.829	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	389	130	P	Q	cCa/cAa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	3,4	deleterious	-3,21	deleterious	-7,31	high_impact	4,63	damaging	0,55	damaging	0,06	deleterious	4,13	23,8	0,29	0,65	disease	0,95	disease	0,86	disease	0,74	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,56	0,9	49,12	8,75	P	0,54	P	0,82	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9976	9976	A	G	MI.8290	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	770	257	Y	C	tAt/tGt	5,68	1	0	probably_damaging	1	neutral	0,05	neutral	0,62	deleterious	-9,08	deleterious	-7,57	high_impact	4,7	neutral	0,66	damaging	0,02	deleterious	3,87	23,5	0,03	0,35	disease	0,88	disease	0,68	disease	0,78	disease	0,79	6	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,82	low_impact	-3,78	medium_impact	-0,54	high_impact	3,03	0,18	0,8	72,8	13,53	P	0,55	P	1	polymorphism	1	0,45	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9976	9976	A	T	MI.8291	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	770	257	Y	F	tAt/tTt	5,68	1	0	probably_damaging	0,99	neutral	0,27	neutral	0,75	deleterious	-4,9	deleterious	-3,41	high_impact	4,14	damaging	0,6	damaging	0,03	deleterious	3,96	23,6	0,12	0,4	neutral	0,43	disease	0,59	disease	0,73	disease	0,72	4	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,76	low_impact	-2,81	medium_impact	-0,06	high_impact	2,53	0,28	0,8	72,8	13,53	P	0,57	P	0,72	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9978	9978	T	G	MI.8292	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	772	258	W	G	Tga/Gga	-0,1	0,8	0	benign	0,1	neutral	0,44	neutral	2,43	neutral	-2,72	deleterious	-10,61	medium_impact	3,43	damaging	0,53	neutral	0,38	deleterious	2,52	19,6	0,04	0,35	neutral	0,4	disease	0,54	disease	0,71	disease	0,7	4	neutral	0,49	deleterious	0,67	neutral	-3	neutral	0,28	medium_impact	0,06	medium_impact	0,13	medium_impact	1,89	0,08	0,8	75,1	12,93	N	0,36	N	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9978	9978	T	C	MI.8293	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	772	258	W	R	Tga/Cga	-0,1	0,8	0	benign	0	neutral	0,07	neutral	2,44	neutral	-2,34	deleterious	-11,42	high_impact	4,12	neutral	0,6	damaging	0,17	deleterious	1,93	15,78	0,04	0,35	neutral	0,28	disease	0,69	disease	0,74	disease	0,72	4	neutral	0,93	deleterious	0,54	neutral	-2	neutral	0,22	high_impact	2,05	medium_impact	-0,45	high_impact	2,51	0,07	0,8	75,1	12,93	N	0,44	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9979	9979	G	C	MI.8294	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	773	258	W	S	tGa/tCa	4,52	1	0	benign	0,09	neutral	0,19	neutral	2,44	neutral	-2,23	deleterious	-11,35	high_impact	4,12	neutral	0,65	neutral	0,33	deleterious	2,67	20,6	0,06	0,35	neutral	0,26	disease	0,66	disease	0,7	disease	0,69	4	neutral	0,79	deleterious	0,55	neutral	-2	neutral	0,3	medium_impact	0,11	medium_impact	-0,17	high_impact	2,51	0,08	0,8	75,1	12,93	P	0,55	P	0,97	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9979	9979	G	T	MI.8295	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	773	258	W	L	tGa/tTa	4,52	1	0	benign	0,06	neutral	0,34	neutral	2,84	neutral	1,38	deleterious	-10,55	low_impact	1,82	neutral	0,61	neutral	0,36	deleterious	2,75	21,1	0,1	0,4	neutral	0,08	disease	0,61	disease	0,66	disease	0,64	3	neutral	0,63	deleterious	0,64	neutral	-6	neutral	0,24	medium_impact	0,29	medium_impact	0,03	medium_impact	0,45	0,06	0,8	75,1	12,93	N	0,48	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9980	9980	A	T	MI.8296	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	774	258	W	C	tgA/tgT	7,3	1	0	possibly_damaging	0,56	neutral	0,12	neutral	2,42	deleterious	-3,19	deleterious	-10,22	medium_impact	2,15	neutral	0,62	damaging	0,17	deleterious	4,26	23,9	0,05	0,35	neutral	0,47	disease	0,68	disease	0,7	disease	0,66	3	neutral	0,88	neutral	0,28	NA	0	deleterious	0,62	medium_impact	-0,97	medium_impact	-0,3	medium_impact	0,74	0,06	0,8	75,1	12,93	N	0,45	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9980	9980	A	C	MI.8297	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	774	258	W	C	tgA/tgC	7,3	1	0	possibly_damaging	0,56	neutral	0,12	neutral	2,42	deleterious	-3,19	deleterious	-10,22	medium_impact	2,15	neutral	0,62	damaging	0,17	deleterious	4,28	24	0,05	0,35	neutral	0,47	disease	0,68	disease	0,7	disease	0,66	3	neutral	0,88	neutral	0,28	NA	0	deleterious	0,62	medium_impact	-0,97	medium_impact	-0,3	medium_impact	0,74	0,06	0,8	75,1	12,93	N	0,45	N	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9981	9981	T	G	MI.8298	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	775	259	W	G	Tga/Gga	6,84	1	0	probably_damaging	0,96	neutral	0,22	neutral	1,75	deleterious	-4,9	deleterious	-10,19	high_impact	3,96	damaging	0,55	damaging	0,13	deleterious	4,12	23,8	0,1	0,4	neutral	0,38	disease	0,55	disease	0,75	disease	0,74	5	neutral	0,98	neutral	0,13	deleterious	2	deleterious	0,72	low_impact	-2,21	medium_impact	-0,12	high_impact	2,37	0,15	0,8	73,56	12,88	N	0,47	N	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9981	9981	T	C	MI.8299	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	775	259	W	R	Tga/Cga	6,84	1	0	probably_damaging	0,99	neutral	0,05	neutral	1,76	deleterious	-4,36	deleterious	-11,1	high_impact	4,3	neutral	0,64	damaging	0,05	deleterious	3,81	23,4	0,12	0,4	neutral	0,34	disease	0,68	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,77	low_impact	-2,81	medium_impact	-0,54	high_impact	2,67	0,06	0,8	73,56	12,88	N	0,45	N	0,99	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8563	8563	A	G	MI.83	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	37	13	T	A	Aca/Gca	-8,89	0	0,12	probably_damaging	0,99	neutral	0,1	neutral	4,58	neutral	-0,53	deleterious	-2,73	medium_impact	2,1	neutral	0,91	neutral	0,7	deleterious	3,22	22,7	0,65	0,7	neutral	0,45	disease	0,55	disease	0,58	disease	0,64	3	deleterious	0,99	neutral	0,06	deleterious	1	deleterious	0,68	low_impact	-2,65	medium_impact	-0,25	medium_impact	0,7	0,41	0,9	15,49	16,77	N	0,46	N	0,74	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8915	8915	C	G	MI.830	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	389	130	P	R	cCa/cGa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	3,4	deleterious	-3,33	deleterious	-8,23	high_impact	4,63	damaging	0,58	damaging	0,06	deleterious	3,54	23,1	0,35	0,65	disease	0,95	disease	0,87	disease	0,78	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,57	0,9	49,12	8,75	P	0,59	P	0,65	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9982	9982	G	C	MI.8300	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	776	259	W	S	tGa/tCa	5,68	1	0	probably_damaging	0,99	neutral	0,34	neutral	1,77	deleterious	-4,14	deleterious	-10,9	high_impact	3,75	neutral	0,69	damaging	0,05	deleterious	4,26	23,9	0,12	0,4	neutral	0,24	disease	0,67	disease	0,74	disease	0,73	5	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,76	low_impact	-2,81	medium_impact	0,03	high_impact	2,18	0,13	0,8	73,56	12,88	N	0,43	N	0,97	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9982	9982	G	T	MI.8301	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	776	259	W	L	tGa/tTa	5,68	1	0	probably_damaging	0,96	neutral	0,15	neutral	1,89	neutral	-2,09	deleterious	-10,35	medium_impact	2,31	neutral	0,62	damaging	0,07	deleterious	4,48	24,2	0,13	0,4	neutral	0,13	disease	0,6	disease	0,72	disease	0,71	4	deleterious	0,98	neutral	0,1	deleterious	1	deleterious	0,71	low_impact	-2,21	medium_impact	-0,24	medium_impact	0,89	0,1	0,8	73,56	12,88	N	0,41	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9983	9983	A	C	MI.8302	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	777	259	W	C	tgA/tgC	7,3	1	0	probably_damaging	0,99	neutral	0,06	neutral	1,74	deleterious	-5,92	deleterious	-10,25	high_impact	4,3	neutral	0,64	damaging	0,04	deleterious	4,24	23,9	0,09	0,35	neutral	0,45	disease	0,67	disease	0,76	disease	0,74	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,77	low_impact	-2,81	medium_impact	-0,49	high_impact	2,67	0,09	0,8	73,56	12,88	N	0,46	N	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9983	9983	A	T	MI.8303	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	777	259	W	C	tgA/tgT	7,3	1	0	probably_damaging	0,99	neutral	0,06	neutral	1,74	deleterious	-5,92	deleterious	-10,25	high_impact	4,3	neutral	0,64	damaging	0,04	deleterious	4,32	24	0,09	0,35	neutral	0,45	disease	0,67	disease	0,76	disease	0,74	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,77	low_impact	-2,81	medium_impact	-0,49	high_impact	2,67	0,09	0,8	73,56	12,88	N	0,47	N	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9984	9984	G	T	MI.8304	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	778	260	G	W	Ggg/Tgg	6,84	1	0	probably_damaging	1	neutral	0,54	neutral	2,03	deleterious	-6,5	deleterious	-6,54	high_impact	4,19	damaging	0,58	damaging	0,02	deleterious	4,76	24,7	0,08	0,35	disease	0,93	disease	0,66	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,78	medium_impact	0,23	high_impact	2,57	0,09	0,8	73,56	12,64	N	0,48	N	0,98	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9984	9984	G	C	MI.8305	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	778	260	G	R	Ggg/Cgg	6,84	1	0	probably_damaging	1	neutral	0,32	neutral	2,11	neutral	-2,81	deleterious	-6,54	medium_impact	2,84	neutral	0,62	damaging	0,03	deleterious	4,23	23,9	0,11	0,4	neutral	0,47	disease	0,57	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,8	low_impact	-3,78	medium_impact	0,01	medium_impact	1,36	0,51	0,8	73,56	12,64	N	0,45	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9985	9985	G	C	MI.8306	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	779	260	G	A	gGg/gCg	9,15	1	0	probably_damaging	0,99	neutral	0,46	neutral	2,09	deleterious	-3,29	deleterious	-4,9	medium_impact	2,95	damaging	0,54	damaging	0,05	deleterious	3,37	22,9	0,16	0,45	neutral	0,46	neutral	0,34	disease	0,55	neutral	0,42	2	deleterious	0,99	neutral	0,24	deleterious	1	deleterious	0,76	low_impact	-2,81	medium_impact	0,15	medium_impact	1,46	0,32	0,8	73,56	12,64	N	0,5	N	0,31	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9985	9985	G	T	MI.8307	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	779	260	G	V	gGg/gTg	9,15	1	0	probably_damaging	1	neutral	0,5	neutral	2,04	deleterious	-5,02	deleterious	-7,36	medium_impact	3,29	damaging	0,51	damaging	0,01	deleterious	4,01	23,6	0,08	0,35	disease	0,67	disease	0,58	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,81	low_impact	-3,78	medium_impact	0,19	medium_impact	1,77	0,1	0,8	73,56	12,64	N	0,44	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9985	9985	G	A	MI.8308	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	779	260	G	E	gGg/gAg	9,15	1	0	probably_damaging	1	neutral	0,25	neutral	2,11	neutral	-2,87	deleterious	-6,54	high_impact	3,64	damaging	0,52	damaging	0,02	deleterious	4,19	23,8	0,11	0,4	disease	0,58	disease	0,56	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,81	low_impact	-3,78	medium_impact	-0,08	high_impact	2,08	0,24	0,8	73,56	12,64	P	0,51	P	0,99	polymorphism	1	0,35	.	.	.	.	.	colonic crypts	COSM1315748	.	.	.	.	.	.	.	.
chrM	9987	9987	T	G	MI.8309	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	781	261	S	A	Tct/Gct	-5,19	0	0	possibly_damaging	0,75	neutral	1	neutral	2,23	neutral	-0,49	neutral	-1,8	low_impact	1,82	neutral	0,6	neutral	0,68	deleterious	1,96	15,93	0,61	0,65	NA	NA	neutral	0,15	neutral	0,27	neutral	0,22	6	neutral	0,75	deleterious	0,63	neutral	-3	deleterious	0,48	low_impact	-1,33	high_impact	1,9	medium_impact	0,45	0,33	0,8	NA	NA	N	0,3	N	0,46	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8915	8915	C	T	MI.831	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	389	130	P	L	cCa/cTa	5,68	1	0	probably_damaging	1	deleterious	0	neutral	3,43	deleterious	-3,61	deleterious	-9,14	high_impact	4,63	damaging	0,54	damaging	0,05	deleterious	4,34	24	0,39	0,65	disease	0,96	disease	0,82	disease	0,71	disease	0,71	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,75	0,9	49,12	8,75	P	0,54	P	0,95	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9987	9987	T	A	MI.8310	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	781	261	S	T	Tct/Act	-5,19	0	0	possibly_damaging	0,62	neutral	0,52	neutral	2,19	neutral	-1,37	neutral	-1,93	medium_impact	2,57	neutral	0,62	neutral	0,49	deleterious	2,12	16,99	0,56	0,6	NA	NA	neutral	0,17	neutral	0,41	neutral	0,21	6	neutral	0,59	neutral	0,45	NA	0	deleterious	0,6	low_impact	-1,08	medium_impact	0,21	medium_impact	1,12	0,44	0,8	NA	NA	N	0,39	N	0,69	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9987	9987	T	C	MI.8311	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	781	261	S	P	Tct/Cct	-5,19	0	0	probably_damaging	0,93	neutral	0,27	neutral	2,13	neutral	-2,9	deleterious	-3,41	medium_impact	3,26	damaging	0,55	neutral	0,41	deleterious	3,82	23,4	0,23	0,45	NA	NA	neutral	0,39	neutral	0,49	neutral	0,19	6	neutral	0,94	neutral	0,17	deleterious	1	deleterious	0,89	low_impact	-1,96	medium_impact	-0,06	medium_impact	1,74	0,43	0,8	NA	NA	N	0,44	N	0,94	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9988	9988	C	T	MI.8312	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	782	261	S	F	tCt/tTt	7,3	1	0	probably_damaging	0,99	neutral	0,11	neutral	2,13	deleterious	-3,58	deleterious	-4,1	low_impact	1,88	damaging	0,59	neutral	0,43	deleterious	4,31	24	0,21	0,45	NA	NA	neutral	0,44	neutral	0,5	neutral	0,24	5	deleterious	0,99	neutral	0,06	neutral	-2	deleterious	0,93	low_impact	-2,81	medium_impact	-0,33	medium_impact	0,5	0,11	0,8	NA	NA	P	0,54	P	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9988	9988	C	G	MI.8313	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	782	261	S	C	tCt/tGt	7,3	1	0	probably_damaging	0,98	neutral	0,12	neutral	2,11	deleterious	-3,71	deleterious	-3,3	medium_impact	2,23	damaging	0,59	neutral	0,39	deleterious	3,63	23,2	0,24	0,45	NA	NA	neutral	0,29	neutral	0,43	neutral	0,19	6	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,93	low_impact	-2,51	medium_impact	-0,3	medium_impact	0,82	0,28	0,8	NA	NA	P	0,59	P	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	9988	9988	C	A	MI.8314	MT-CO3	IV	ENSG00000198938	ENSP00000354982	ENST00000362079	COX3_HUMAN	P00414	4514	YP_003024032.1	782	261	S	Y	tCt/tAt	7,3	1	0	probably_damaging	0,99	neutral	0,13	neutral	2,17	deleterious	-3,7	deleterious	-4	low_impact	1,4	damaging	0,59	neutral	0,32	deleterious	4,17	23,8	0,23	0,45	NA	NA	neutral	0,43	disease	0,52	neutral	0,39	2	deleterious	0,99	neutral	0,07	neutral	-2	deleterious	0,93	low_impact	-2,81	medium_impact	-0,28	medium_impact	0,07	0,28	0,8	NA	NA	P	0,51	P	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14747	14747	A	C	MI.8315	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1	1	M	L	Atg/Ctg	2,02	0,8	0	possibly_damaging	0,75	deleterious	0	neutral	4,79	neutral	1,23	neutral	-1,02	NA	NA	neutral	0,89	damaging	0,07	neutral	1,34	12,49	0,09	0,35	neutral	0,21	neutral	0,16	neutral	0,26	neutral	0,3	4	deleterious	1	neutral	0,13	deleterious	3	deleterious	0,52	NA	NA	NA	NA	NA	NA	0,16	0,8	57,37	8,8	N	0,38	N	0,93	NA	NA	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14747	14747	A	T	MI.8316	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1	1	M	L	Atg/Ttg	2,02	0,8	0	possibly_damaging	0,75	deleterious	0	neutral	4,79	neutral	1,23	neutral	-1,02	NA	NA	neutral	0,89	damaging	0,07	neutral	1,39	12,71	0,09	0,35	neutral	0,21	neutral	0,16	neutral	0,26	neutral	0,3	4	deleterious	1	neutral	0,13	deleterious	3	deleterious	0,52	NA	NA	NA	NA	NA	NA	0,16	0,8	57,37	8,8	N	0,38	N	0,93	NA	NA	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14747	14747	A	G	MI.8317	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	1	1	M	V	Atg/Gtg	2,02	0,8	0	possibly_damaging	0,83	deleterious	0	neutral	4,68	neutral	0,74	neutral	-1,23	NA	NA	neutral	0,84	damaging	0,09	deleterious	0,73	9,05	0,14	0,4	neutral	0,17	neutral	0,21	neutral	0,43	neutral	0,36	3	deleterious	1	neutral	0,09	deleterious	3	deleterious	0,57	NA	NA	NA	NA	NA	NA	0,17	0,8	57,37	8,8	N	0,32	N	0,99	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14748	14748	T	A	MI.8318	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	2	1	M	K	aTg/aAg	6,38	1	0	probably_damaging	0,92	deleterious	0	neutral	4,59	neutral	-0,31	neutral	-1,93	NA	NA	neutral	0,87	damaging	0,07	deleterious	2,02	16,35	0,1	0,4	neutral	0,33	neutral	0,36	disease	0,6	neutral	0,44	1	deleterious	1	neutral	0,04	deleterious	4	deleterious	0,73	NA	NA	NA	NA	NA	NA	0,06	0,8	57,37	8,8	P	0,54	P	0,99	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14748	14748	T	C	MI.8319	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	2	1	M	T	aTg/aCg	6,38	1	0	probably_damaging	0,92	deleterious	0	neutral	4,59	neutral	-0,39	neutral	-1,48	NA	NA	neutral	0,88	damaging	0,09	deleterious	0,88	9,94	0,11	0,4	neutral	0,29	neutral	0,32	neutral	0,46	neutral	0,41	2	deleterious	1	neutral	0,04	deleterious	4	deleterious	0,73	NA	NA	NA	NA	NA	NA	0,03	0,8	57,37	8,8	P	0,52	P	0,99	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8917	8917	C	A	MI.832	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	391	131	Q	K	Caa/Aaa	-4,5	0	0	probably_damaging	0,97	neutral	0,53	neutral	4,39	neutral	-0,05	deleterious	-2,52	low_impact	1,82	neutral	0,82	damaging	0,14	deleterious	3,97	23,6	0,57	0,65	neutral	0,37	disease	0,67	neutral	0,47	neutral	0,41	2	neutral	0,97	neutral	0,28	neutral	-2	deleterious	0,71	low_impact	-2,19	medium_impact	0,32	medium_impact	0,46	0,59	0,9	44,69	8,63	N	0,18	N	0,99	polymorphism	0,97	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14749	14749	G	T	MI.8320	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	3	1	M	I	atG/atT	7,07	1	0	possibly_damaging	0,88	deleterious	0	neutral	4,68	neutral	0,61	neutral	-1,33	NA	NA	neutral	0,89	damaging	0,06	neutral	1,6	13,87	0,11	0,4	neutral	0,19	neutral	0,21	neutral	0,4	neutral	0,34	3	deleterious	1	neutral	0,06	deleterious	3	deleterious	0,65	NA	NA	NA	NA	NA	NA	0,25	0,8	57,37	8,8	P	0,55	P	0,99	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14749	14749	G	C	MI.8321	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	3	1	M	I	atG/atC	7,07	1	0	possibly_damaging	0,88	deleterious	0	neutral	4,68	neutral	0,61	neutral	-1,33	NA	NA	neutral	0,89	damaging	0,06	neutral	1,44	13,01	0,11	0,4	neutral	0,19	neutral	0,21	neutral	0,4	neutral	0,34	3	deleterious	1	neutral	0,06	deleterious	3	deleterious	0,65	NA	NA	NA	NA	NA	NA	0,25	0,8	57,37	8,8	P	0,55	P	0,99	NA	NA	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14750	14750	A	C	MI.8322	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	4	2	T	P	Acc/Ccc	6,84	1	0,01	benign	0,12	neutral	0,36	neutral	4,57	neutral	-1,01	neutral	-1,68	medium_impact	2,74	neutral	0,96	neutral	0,3	neutral	1,44	13,01	0,15	0,45	neutral	0,17	neutral	0,33	neutral	0,08	neutral	0,46	1	neutral	0,58	deleterious	0,62	neutral	-3	neutral	0,32	medium_impact	0,08	medium_impact	0,09	medium_impact	1,29	0,28	0,8	44,74	8,4	P	0,6	P	0,96	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14750	14750	A	G	MI.8323	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	4	2	T	A	Acc/Gcc	6,84	1	0,01	benign	0	neutral	1	neutral	4,75	neutral	-0,19	neutral	-0,8	low_impact	0,83	neutral	0,98	neutral	0,71	deleterious	0	2,58	0,44	0,55	neutral	0,26	neutral	0,02	neutral	0,07	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,05	high_impact	2,07	high_impact	1,85	medium_impact	-0,44	0,18	0,8	44,74	8,4	N	0,53	P	0,6	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14750	14750	A	T	MI.8324	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	4	2	T	S	Acc/Tcc	6,84	1	0,01	benign	0,01	neutral	0,71	neutral	4,67	neutral	0,05	neutral	-0,95	medium_impact	2,6	neutral	0,96	neutral	0,47	neutral	1,17	11,6	0,62	0,65	neutral	0,31	neutral	0,13	neutral	0,06	neutral	0,28	4	neutral	0,27	deleterious	0,85	neutral	-3	neutral	0,08	medium_impact	1,13	medium_impact	0,43	medium_impact	1,17	0,52	0,8	44,74	8,4	N	0,53	P	0,79	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14751	14751	C	T	MI.8325	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	5	2	T	I	aCc/aTc	1,33	0,99	0,01	benign	0,1	neutral	0,47	neutral	4,62	neutral	-2,6	neutral	-1,43	medium_impact	2,62	neutral	0,95	neutral	0,66	deleterious	1,96	15,95	0,34	0,5	neutral	0,26	neutral	0,22	neutral	0,21	neutral	0,43	2	neutral	0,46	deleterious	0,69	neutral	-3	neutral	0,27	medium_impact	0,16	medium_impact	0,19	medium_impact	1,19	0,24	0,8	44,74	8,4	N	0,51	P	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14751	14751	C	G	MI.8326	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	5	2	T	S	aCc/aGc	1,33	0,99	0,01	benign	0,01	neutral	0,71	neutral	4,67	neutral	0,05	neutral	-0,95	medium_impact	2,6	neutral	0,96	neutral	0,47	neutral	1,36	12,58	0,62	0,65	neutral	0,31	neutral	0,13	neutral	0,06	neutral	0,28	4	neutral	0,27	deleterious	0,85	neutral	-3	neutral	0,08	medium_impact	1,13	medium_impact	0,43	medium_impact	1,17	0,52	0,8	44,74	8,4	N	0,43	N	0,79	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14751	14751	C	A	MI.8327	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	5	2	T	N	aCc/aAc	1,33	0,99	0,01	benign	0,12	neutral	0,58	neutral	4,6	neutral	0,13	neutral	-1,35	medium_impact	3,43	neutral	0,96	neutral	0,63	neutral	1,57	13,67	0,54	0,6	neutral	0,43	neutral	0,23	neutral	0,09	neutral	0,44	1	neutral	0,32	deleterious	0,73	neutral	-3	neutral	0,23	medium_impact	0,08	medium_impact	0,3	medium_impact	1,92	0,32	0,8	44,74	8,4	N	0,43	N	0,86	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14753	14753	C	A	MI.8328	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	7	3	P	T	Cca/Aca	-2,11	0	0	benign	0,31	neutral	0,72	neutral	4,74	neutral	0,28	neutral	0,14	low_impact	0,92	neutral	0,95	neutral	0,74	deleterious	2,18	17,37	0,33	0,5	neutral	0,3	neutral	0,09	neutral	0,15	neutral	0,33	3	neutral	0,22	deleterious	0,71	neutral	-6	neutral	0,23	medium_impact	-0,41	medium_impact	0,44	medium_impact	-0,36	0,44	0,8	25,53	51,21	N	0,4	N	0,36	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14753	14753	C	T	MI.8329	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	7	3	P	S	Cca/Tca	-2,11	0	0	benign	0,02	neutral	0,92	neutral	4,78	neutral	0,16	neutral	0,43	neutral_impact	-0,06	neutral	0,94	neutral	0,78	deleterious	2,04	16,45	0,41	0,5	neutral	0,24	neutral	0,05	neutral	0,11	neutral	0,27	5	neutral	0,03	deleterious	0,95	neutral	-6	neutral	0,07	medium_impact	0,85	medium_impact	0,8	low_impact	-1,25	0,32	0,8	25,53	51,21	N	0,37	N	0,01	polymorphism	1	0,01	rs527236162	Likely pathogenic	Neoplasm_of_ovary	RCV000133404.1	Gene:MedGen:OMIM:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	8917	8917	C	G	MI.833	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	391	131	Q	E	Caa/Gaa	-4,5	0	0	probably_damaging	0,94	neutral	1	neutral	4,37	neutral	-0,2	neutral	-0,61	neutral_impact	-0,48	neutral	0,77	neutral	0,56	deleterious	0,38	6,41	0,62	0,7	neutral	0,31	neutral	0,08	neutral	0,19	neutral	0,29	4	neutral	0,94	deleterious	0,53	neutral	-2	deleterious	0,63	low_impact	-1,89	high_impact	1,98	low_impact	-1,51	0,59	0,9	44,69	8,63	N	0,32	N	0,94	polymorphism	0,98	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14753	14753	C	G	MI.8330	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	7	3	P	A	Cca/Gca	-2,11	0	0	benign	0,14	neutral	0,93	neutral	4,77	neutral	0,48	neutral	-0,29	low_impact	1,38	neutral	0,95	neutral	0,71	deleterious	2,55	19,78	0,37	0,5	neutral	0,17	neutral	0,06	neutral	0,3	neutral	0,27	5	neutral	0,05	deleterious	0,9	neutral	-6	neutral	0,14	medium_impact	0	medium_impact	0,83	medium_impact	0,06	0,59	0,8	25,53	51,21	N	0,35	N	0,43	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14754	14754	C	T	MI.8331	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	8	3	P	L	cCa/cTa	1,33	0	0	possibly_damaging	0,52	neutral	0,89	neutral	4,72	neutral	1,03	neutral	-0,56	low_impact	1,82	neutral	0,95	neutral	0,53	deleterious	4,01	23,6	0,27	0,45	neutral	0,4	neutral	0,12	neutral	0,39	neutral	0,35	3	neutral	0,44	deleterious	0,69	neutral	-3	neutral	0,33	medium_impact	-0,76	medium_impact	0,71	medium_impact	0,46	0,5	0,8	25,53	51,21	N	0,29	N	0,59	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14754	14754	C	G	MI.8332	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	8	3	P	R	cCa/cGa	1,33	0	0	possibly_damaging	0,71	neutral	0,63	neutral	4,72	neutral	-0,02	neutral	-0,35	low_impact	1,82	neutral	0,95	neutral	0,48	deleterious	3,32	22,9	0,23	0,45	neutral	0,31	neutral	0,26	neutral	0,4	neutral	0,45	1	neutral	0,65	neutral	0,46	neutral	-3	deleterious	0,46	low_impact	-1,09	medium_impact	0,35	medium_impact	0,46	0,32	0,8	25,53	51,21	N	0,31	N	0,48	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14754	14754	C	A	MI.8333	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	8	3	P	Q	cCa/cAa	1,33	0	0	possibly_damaging	0,7	neutral	0,62	neutral	4,72	neutral	-0,49	neutral	-0,17	low_impact	1,73	neutral	0,95	neutral	0,53	deleterious	3,83	23,4	0,26	0,45	neutral	0,2	neutral	0,14	neutral	0,4	neutral	0,33	3	neutral	0,65	neutral	0,46	neutral	-3	deleterious	0,44	low_impact	-1,07	medium_impact	0,34	medium_impact	0,38	0,32	0,8	25,53	51,21	N	0,35	N	0,39	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14756	14756	A	C	MI.8334	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	10	4	M	L	Ata/Cta	-0,04	0	0	benign	0	neutral	0,44	neutral	4,9	neutral	1,96	neutral	0,14	neutral_impact	-0,94	neutral	0,98	neutral	0,93	neutral	-1,04	0,01	0,32	0,5	neutral	0,19	neutral	0,04	neutral	0,22	neutral	0,2	6	neutral	0,56	deleterious	0,72	neutral	-6	neutral	0,05	high_impact	2,07	medium_impact	0,17	low_impact	-2,05	0,09	0,8	26,32	48,86	N	0,49	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14756	14756	A	T	MI.8335	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	10	4	M	L	Ata/Tta	-0,04	0	0	benign	0	neutral	0,44	neutral	4,9	neutral	1,96	neutral	0,14	neutral_impact	-0,94	neutral	0,98	neutral	0,93	neutral	-0,9	0,03	0,32	0,5	neutral	0,19	neutral	0,04	neutral	0,22	neutral	0,2	6	neutral	0,56	deleterious	0,72	neutral	-6	neutral	0,05	high_impact	2,07	medium_impact	0,17	low_impact	-2,05	0,09	0,8	26,32	48,86	N	0,5	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14756	14756	A	G	MI.8336	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	10	4	M	V	Ata/Gta	-0,04	0	0	benign	0,01	neutral	0,37	neutral	4,79	neutral	1,31	neutral	-0,52	medium_impact	2,05	neutral	0,97	neutral	0,7	deleterious	0,85	9,76	0,38	0,5	neutral	0,22	neutral	0,18	neutral	0,36	neutral	0,34	3	neutral	0,62	deleterious	0,68	neutral	-3	neutral	0,08	medium_impact	1,13	medium_impact	0,1	medium_impact	0,67	0,09	0,8	26,32	48,86	N	0,41	N	0,22	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14757	14757	T	C	MI.8337	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	11	4	M	T	aTa/aCa	0,64	0	0	benign	0	neutral	0,62	neutral	4,71	neutral	-0,12	neutral	-1,13	neutral_impact	0,69	neutral	0,99	neutral	0,97	neutral	-0,28	0,72	0,22	0,45	neutral	0,29	neutral	0,17	neutral	0,4	neutral	0,31	4	neutral	0,38	deleterious	0,81	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,34	medium_impact	-0,57	0,04	0,8	26,32	48,86	N	0,39	N	0,01	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14757	14757	T	A	MI.8338	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	11	4	M	K	aTa/aAa	0,64	0	0	benign	0,03	neutral	0,94	neutral	4,68	neutral	-0,32	neutral	-1,79	medium_impact	2,46	neutral	0,95	neutral	0,49	deleterious	2,16	17,23	0,17	0,45	neutral	0,48	neutral	0,38	disease	0,67	neutral	0,48	0	neutral	0,01	deleterious	0,96	neutral	-3	neutral	0,16	medium_impact	0,68	medium_impact	0,87	medium_impact	1,04	0,11	0,8	26,32	48,86	N	0,25	N	0,48	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14758	14758	A	C	MI.8339	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	12	4	M	I	atA/atC	1,56	0	0	benign	0,01	neutral	0,27	neutral	4,8	neutral	1,29	neutral	-0,3	neutral_impact	-0,28	neutral	0,96	neutral	0,97	neutral	-1,23	0,01	0,3	0,45	neutral	0,15	neutral	0,05	neutral	0,21	neutral	0,24	5	neutral	0,73	deleterious	0,63	neutral	-6	neutral	0,06	medium_impact	1,13	medium_impact	-0,01	low_impact	-1,45	0,14	0,8	26,32	48,86	N	0,5	N	0,01	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8918	8918	A	C	MI.834	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	392	131	Q	P	cAa/cCa	4,52	1	0	probably_damaging	0,98	neutral	0,18	neutral	4,43	neutral	0,36	deleterious	-4,35	low_impact	1,86	neutral	0,69	damaging	0,17	deleterious	3,24	22,8	0,19	0,65	disease	0,68	disease	0,83	neutral	0,43	disease	0,67	3	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,83	low_impact	-2,36	medium_impact	-0,08	medium_impact	0,5	0,41	0,9	44,69	8,63	N	0,37	N	0,98	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14758	14758	A	T	MI.8340	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	12	4	M	I	atA/atT	1,56	0	0	benign	0,01	neutral	0,27	neutral	4,8	neutral	1,29	neutral	-0,3	neutral_impact	-0,28	neutral	0,96	neutral	0,97	neutral	-1,16	0,01	0,3	0,45	neutral	0,15	neutral	0,05	neutral	0,21	neutral	0,24	5	neutral	0,73	deleterious	0,63	neutral	-6	neutral	0,06	medium_impact	1,13	medium_impact	-0,01	low_impact	-1,45	0,14	0,8	26,32	48,86	P	0,51	P	0,01	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14759	14759	C	A	MI.8341	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	13	5	R	S	Cgc/Agc	-11,28	0	0	probably_damaging	0,95	neutral	0,44	neutral	4,6	neutral	-0,35	deleterious	-3,01	high_impact	4,29	neutral	0,95	neutral	0,34	deleterious	2,63	20,4	0,09	0,4	disease	0,54	disease	0,52	disease	0,64	disease	0,65	3	neutral	0,95	neutral	0,25	deleterious	2	deleterious	0,74	low_impact	-1,92	medium_impact	0,17	high_impact	2,7	0,22	0,8	58,95	8,56	N	0,4	N	0,77	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14759	14759	C	G	MI.8342	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	13	5	R	G	Cgc/Ggc	-11,28	0	0	probably_damaging	0,95	neutral	0,34	neutral	4,54	neutral	-1,47	deleterious	-3,51	high_impact	3,81	neutral	0,96	neutral	0,36	deleterious	2,24	17,78	0,1	0,4	disease	0,69	neutral	0,42	disease	0,67	disease	0,58	2	neutral	0,95	neutral	0,2	deleterious	2	deleterious	0,74	low_impact	-1,92	medium_impact	0,07	high_impact	2,27	0,13	0,8	58,95	8,56	N	0,41	N	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14759	14759	C	T	MI.8343	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	13	5	R	C	Cgc/Tgc	-11,28	0	0	probably_damaging	0,99	neutral	0,18	neutral	4,51	deleterious	-3,22	deleterious	-4,01	high_impact	4,84	neutral	0,95	damaging	0,17	deleterious	3,33	22,9	0,08	0,35	disease	0,89	disease	0,53	disease	0,7	disease	0,74	5	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	-0,14	high_impact	3,2	0,57	0,8	58,95	8,56	P	0,64	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14760	14760	G	T	MI.8344	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	14	5	R	L	cGc/cTc	1,56	0,54	0	possibly_damaging	0,89	neutral	0,69	neutral	4,6	neutral	0,04	deleterious	-3,47	high_impact	3,52	neutral	0,94	damaging	0,27	deleterious	2,35	18,52	0,11	0,4	disease	0,63	disease	0,61	disease	0,65	disease	0,66	3	neutral	0,87	neutral	0,4	deleterious	1	deleterious	0,75	low_impact	-1,58	medium_impact	0,41	high_impact	2	0,01	0,8	58,95	8,56	N	0,27	N	1	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14760	14760	G	A	MI.8345	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	14	5	R	H	cGc/cAc	1,56	0,54	0	probably_damaging	0,97	neutral	0,55	neutral	4,53	neutral	-1,8	deleterious	-2,52	medium_impact	3,46	neutral	0,93	damaging	0,21	deleterious	2,59	20,1	0,23	0,45	neutral	0,4	neutral	0,48	disease	0,55	disease	0,51	0	neutral	0,97	neutral	0,29	deleterious	1	deleterious	0,73	low_impact	-2,14	medium_impact	0,27	medium_impact	1,95	0,48	0,8	58,95	8,56	N	0,27	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14760	14760	G	C	MI.8346	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	14	5	R	P	cGc/cCc	1,56	0,54	0	probably_damaging	0,98	neutral	0,21	neutral	4,53	neutral	-1,75	deleterious	-3,51	medium_impact	3,46	neutral	0,93	damaging	0,21	deleterious	2,38	18,68	0,05	0,35	disease	0,61	disease	0,58	disease	0,66	disease	0,67	3	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,78	low_impact	-2,31	medium_impact	-0,09	medium_impact	1,95	0,15	0,8	58,95	8,56	N	0,36	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14762	14762	A	G	MI.8347	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	16	6	K	E	Aaa/Gaa	-2,8	0	0	probably_damaging	0,95	neutral	0,69	neutral	4,42	neutral	-1,7	neutral	-2,08	medium_impact	3,12	neutral	0,86	neutral	0,4	deleterious	2,19	17,41	0,24	0,45	neutral	0,49	disease	0,62	disease	0,67	disease	0,68	4	neutral	0,94	neutral	0,37	deleterious	1	deleterious	0,76	low_impact	-1,92	medium_impact	0,41	medium_impact	1,64	0,53	0,8	58,95	8,87	N	0,2	N	0,95	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14762	14762	A	C	MI.8348	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	16	6	K	Q	Aaa/Caa	-2,8	0	0	probably_damaging	0,95	neutral	0,52	neutral	4,4	neutral	-1,92	neutral	-2,08	high_impact	3,75	neutral	0,96	neutral	0,44	neutral	1,59	13,8	0,39	0,5	disease	0,54	disease	0,58	neutral	0,5	disease	0,5	0	neutral	0,94	neutral	0,29	deleterious	2	deleterious	0,73	low_impact	-1,92	medium_impact	0,24	high_impact	2,21	0,37	0,8	58,95	8,87	N	0,32	N	0,93	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14763	14763	A	C	MI.8349	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	17	6	K	T	aAa/aCa	8,44	1	0	probably_damaging	0,98	neutral	0,64	neutral	4,37	neutral	-2,44	deleterious	-3,12	high_impact	4,18	neutral	0,93	neutral	0,45	deleterious	1,94	15,83	0,09	0,4	disease	0,58	disease	0,6	disease	0,55	disease	0,54	1	deleterious	0,98	neutral	0,33	deleterious	2	deleterious	0,78	low_impact	-2,31	medium_impact	0,36	high_impact	2,6	0,18	0,8	58,95	8,87	P	0,55	P	0,88	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8918	8918	A	G	MI.835	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	392	131	Q	R	cAa/cGa	4,52	1	0	probably_damaging	0,97	neutral	0,21	neutral	4,3	neutral	-1,24	deleterious	-2,86	medium_impact	2,6	neutral	0,86	damaging	0,15	deleterious	3,34	22,9	0,56	0,65	neutral	0,48	disease	0,73	disease	0,58	disease	0,69	4	deleterious	0,98	neutral	0,12	deleterious	1	deleterious	0,78	low_impact	-2,19	medium_impact	-0,03	medium_impact	1,13	0,36	0,9	44,69	8,63	N	0,42	N	0,91	disease_causing	0,98	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14763	14763	A	T	MI.8350	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	17	6	K	M	aAa/aTa	8,44	1	0	probably_damaging	0,99	neutral	0,26	neutral	4,32	deleterious	-4,03	deleterious	-3,12	high_impact	4,43	neutral	0,96	neutral	0,46	deleterious	3,63	23,2	0,1	0,4	disease	0,79	disease	0,61	disease	0,64	disease	0,69	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,76	low_impact	-2,59	medium_impact	-0,02	high_impact	2,83	0,17	0,8	58,95	8,87	P	0,64	P	0,67	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14764	14764	A	T	MI.8351	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	18	6	K	N	aaA/aaT	6,61	1	0	probably_damaging	0,99	neutral	0,59	neutral	4,38	neutral	-2,46	deleterious	-2,6	medium_impact	3,16	neutral	0,93	neutral	0,43	deleterious	2,23	17,69	0,46	0,55	neutral	0,44	disease	0,53	disease	0,53	disease	0,57	1	deleterious	0,99	neutral	0,3	deleterious	1	deleterious	0,74	low_impact	-2,59	medium_impact	0,31	medium_impact	1,68	0,36	0,8	58,95	8,87	N	0,52	P	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14764	14764	A	C	MI.8352	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	18	6	K	N	aaA/aaC	6,61	1	0	probably_damaging	0,99	neutral	0,59	neutral	4,38	neutral	-2,46	deleterious	-2,6	medium_impact	3,16	neutral	0,93	neutral	0,43	deleterious	2,2	17,48	0,46	0,55	neutral	0,44	disease	0,53	disease	0,53	disease	0,57	1	deleterious	0,99	neutral	0,3	deleterious	1	deleterious	0,74	low_impact	-2,59	medium_impact	0,31	medium_impact	1,68	0,36	0,8	58,95	8,87	N	0,51	P	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14765	14765	A	C	MI.8353	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	19	7	T	P	Act/Cct	2,48	0,98	0	benign	0,4	neutral	0,29	neutral	4,6	neutral	-1,16	neutral	-2,38	NA	NA	neutral	0,99	neutral	0,36	neutral	1,44	12,99	0,04	0,35	neutral	0,39	disease	0,65	disease	0,61	disease	0,66	3	neutral	0,66	neutral	0,45	neutral	-4	deleterious	0,46	NA	NA	NA	NA	NA	NA	0,33	0,8	17,89	14,22	N	0,5	N	0,61	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14765	14765	A	G	MI.8354	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	19	7	T	A	Act/Gct	2,48	0,98	0	benign	0,01	neutral	0,69	neutral	4,68	neutral	-0,54	neutral	-1,74	NA	NA	neutral	0,99	neutral	0,63	neutral	1,37	12,62	0,25	0,45	neutral	0,17	neutral	0,27	disease	0,53	neutral	0,46	1	neutral	0,3	deleterious	0,84	neutral	-4	neutral	0,07	NA	NA	NA	NA	NA	NA	0,2	0,8	17,89	14,22	N	0,41	N	0,1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14765	14765	A	T	MI.8355	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	19	7	T	S	Act/Tct	2,48	0,98	0	benign	0,11	neutral	0,72	neutral	4,71	neutral	-0,05	neutral	-1,05	NA	NA	neutral	0,97	neutral	0,97	neutral	-1,03	0,01	0,37	0,5	neutral	0,27	neutral	0,11	neutral	0,3	neutral	0,26	5	neutral	0,17	deleterious	0,81	neutral	-4	neutral	0,11	NA	NA	NA	NA	NA	NA	0,55	0,8	17,89	14,22	N	0,5	N	0	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14766	14766	C	A	MI.8356	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	20	7	T	N	aCt/aAt	-0,04	0	0,83	possibly_damaging	0,48	neutral	0,54	neutral	4,65	neutral	-0,53	neutral	-1,63	NA	NA	neutral	0,96	neutral	0,87	deleterious	0,65	8,49	0,43	0,55	neutral	0,21	neutral	0,4	neutral	0,41	neutral	0,43	1	neutral	0,45	deleterious	0,53	neutral	-1	neutral	0,41	NA	NA	NA	NA	NA	NA	0,5	0,8	17,89	14,22	N	0,33	N	0,04	polymorphism	1	0,02	rs193302980	Likely pathogenic	Familial_cancer_of_breast	RCV000128802.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	14766	14766	C	T	MI.8357	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	20	7	T	I	aCt/aTt	-0,04	0	0,83	benign	0,01	neutral	0,21	neutral	4,61	neutral	-1,54	neutral	-2,35	NA	NA	neutral	0,98	neutral	0,62	deleterious	1,93	15,79	0,12	0,4	neutral	0,17	disease	0,52	disease	0,6	neutral	0,48	0	neutral	0,79	deleterious	0,6	neutral	-4	neutral	0,09	NA	NA	NA	NA	NA	NA	0,32	0,8	17,89	14,22	N	0,48	N	0,09	polymorphism	1	0,08	rs193302980,rs527236041	Likely pathogenic	Familial_cancer_of_breast	RCV000128802.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	0,74	.	.	.	.	.	.
chrM	14766	14766	C	G	MI.8358	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	20	7	T	S	aCt/aGt	-0,04	0	0,83	benign	0,11	neutral	0,72	neutral	4,71	neutral	-0,05	neutral	-1,05	NA	NA	neutral	0,97	neutral	0,97	neutral	-0,64	0,1	0,37	0,5	neutral	0,27	neutral	0,11	neutral	0,3	neutral	0,26	5	neutral	0,17	deleterious	0,81	neutral	-4	neutral	0,11	NA	NA	NA	NA	NA	NA	0,55	0,8	17,89	14,22	N	0,39	N	0	polymorphism	1	0,02	rs193302980	Likely pathogenic	Familial_cancer_of_breast	RCV000128802.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	14768	14768	A	G	MI.8359	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	22	8	N	D	Aac/Gac	-8,99	0	0	probably_damaging	0,98	neutral	0,33	neutral	4,65	neutral	-0,78	neutral	-1,38	low_impact	0,99	neutral	0,95	neutral	0,55	deleterious	2	16,2	0,43	0,55	neutral	0,39	neutral	0,35	disease	0,67	neutral	0,46	1	deleterious	0,98	neutral	0,18	neutral	-2	deleterious	0,69	low_impact	-2,31	medium_impact	0,06	medium_impact	-0,29	0,33	0,8	21,32	58,66	N	0,34	N	0,67	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8918	8918	A	T	MI.836	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	392	131	Q	L	cAa/cTa	4,52	1	0	probably_damaging	0,97	neutral	0,37	neutral	4,29	neutral	-1,52	deleterious	-5,44	low_impact	1,24	neutral	0,89	neutral	0,69	deleterious	3,63	23,2	0,52	0,65	neutral	0,3	disease	0,56	neutral	0,38	neutral	0,34	3	neutral	0,97	neutral	0,2	neutral	-2	deleterious	0,71	low_impact	-2,19	medium_impact	0,16	medium_impact	-0,04	0,26	0,9	44,69	8,63	N	0,51	P	0,99	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14768	14768	A	C	MI.8360	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	22	8	N	H	Aac/Cac	-8,99	0	0	probably_damaging	1	neutral	0,59	neutral	4,7	neutral	0,62	neutral	2,67	neutral_impact	-2,67	neutral	0,93	neutral	0,93	deleterious	-0,06	2,07	0,27	0,45	neutral	0,18	neutral	0,04	neutral	0,36	neutral	0,17	7	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,61	low_impact	-3,53	medium_impact	0,31	low_impact	-3,62	0,2	0,8	21,32	58,66	N	0,31	N	0,03	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14768	14768	A	T	MI.8361	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	22	8	N	Y	Aac/Tac	-8,99	0	0	probably_damaging	1	neutral	1	neutral	4,61	neutral	0,4	neutral	-0,28	neutral_impact	0,49	neutral	0,97	neutral	0,7	deleterious	3,31	22,9	0,12	0,4	disease	0,63	neutral	0,36	disease	0,66	disease	0,62	2	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,75	low_impact	-3,53	high_impact	1,85	medium_impact	-0,75	0,2	0,8	21,32	58,66	N	0,25	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14769	14769	A	T	MI.8362	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	23	8	N	I	aAc/aTc	2,71	0,99	0	probably_damaging	1	neutral	0,44	neutral	4,64	neutral	0,71	deleterious	-2,62	neutral_impact	0,64	neutral	0,96	neutral	0,59	deleterious	3,52	23,1	0,13	0,4	neutral	0,29	neutral	0,49	disease	0,65	disease	0,59	2	deleterious	1	neutral	0,22	neutral	-2	deleterious	0,7	low_impact	-3,53	medium_impact	0,17	medium_impact	-0,61	0,21	0,8	21,32	58,66	N	0,41	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14769	14769	A	C	MI.8363	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	23	8	N	T	aAc/aCc	2,71	0,99	0	probably_damaging	0,99	neutral	0,52	neutral	4,67	neutral	0,27	neutral	-1,9	low_impact	1,29	neutral	0,96	neutral	0,65	neutral	1,58	13,76	0,22	0,45	neutral	0,39	neutral	0,29	disease	0,66	neutral	0,44	1	deleterious	0,99	neutral	0,27	neutral	-2	deleterious	0,68	low_impact	-2,59	medium_impact	0,24	medium_impact	-0,02	0,31	0,8	21,32	58,66	N	0,42	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14769	14769	A	G	MI.8364	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	23	8	N	S	aAc/aGc	2,71	0,99	0	probably_damaging	0,98	neutral	0,58	neutral	4,69	neutral	0,07	neutral	-1,35	low_impact	0,87	neutral	0,97	neutral	0,66	neutral	1,25	11,99	0,38	0,5	neutral	0,34	neutral	0,25	disease	0,6	neutral	0,43	1	deleterious	0,98	neutral	0,3	neutral	-2	deleterious	0,67	low_impact	-2,31	medium_impact	0,3	medium_impact	-0,4	0,2	0,8	21,32	58,66	N	0,34	N	0,27	polymorphism	1	0,02	rs28357679	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14770	14770	C	A	MI.8365	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	24	8	N	K	aaC/aaA	5,46	1	0	probably_damaging	0,99	neutral	0,5	neutral	4,71	neutral	-0,13	neutral	-1,47	low_impact	1,22	neutral	0,96	neutral	0,54	deleterious	2,67	20,6	0,29	0,45	neutral	0,29	neutral	0,42	disease	0,69	neutral	0,46	1	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,69	low_impact	-2,59	medium_impact	0,22	medium_impact	-0,09	0,3	0,8	21,32	58,66	N	0,5	N	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14770	14770	C	G	MI.8366	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	24	8	N	K	aaC/aaG	5,46	1	0	probably_damaging	0,99	neutral	0,5	neutral	4,71	neutral	-0,13	neutral	-1,47	low_impact	1,22	neutral	0,96	neutral	0,54	deleterious	2,23	17,74	0,29	0,45	neutral	0,29	neutral	0,42	disease	0,69	neutral	0,46	1	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,69	low_impact	-2,59	medium_impact	0,22	medium_impact	-0,09	0,3	0,8	21,32	58,66	N	0,5	N	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14771	14771	C	T	MI.8367	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	25	9	P	S	Ccc/Tcc	-0,04	0,87	0	probably_damaging	0,98	neutral	0,41	neutral	4,55	neutral	-1,09	deleterious	-4,38	high_impact	3,63	neutral	0,92	damaging	0,11	deleterious	1,88	15,45	0,14	0,4	neutral	0,41	disease	0,73	disease	0,52	disease	0,54	1	neutral	0,98	neutral	0,22	deleterious	2	deleterious	0,76	low_impact	-2,31	medium_impact	0,14	high_impact	2,1	0,14	0,8	24,21	8,33	N	0,35	N	0,85	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14771	14771	C	G	MI.8368	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	25	9	P	A	Ccc/Gcc	-0,04	0,87	0	probably_damaging	0,91	neutral	0,5	neutral	4,55	neutral	-1,11	deleterious	-4,39	high_impact	3,68	neutral	0,94	damaging	0,15	neutral	1,02	10,8	0,14	0,4	neutral	0,3	disease	0,56	disease	0,61	disease	0,64	3	neutral	0,9	neutral	0,3	deleterious	2	deleterious	0,69	low_impact	-1,67	medium_impact	0,22	high_impact	2,15	0,33	0,8	24,21	8,33	N	0,34	N	0,82	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14771	14771	C	A	MI.8369	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	25	9	P	T	Ccc/Acc	-0,04	0,87	0	probably_damaging	0,98	neutral	0,39	neutral	4,53	neutral	-1,52	deleterious	-4,39	high_impact	3,73	neutral	0,92	damaging	0,11	deleterious	1,9	15,57	0,14	0,4	neutral	0,44	disease	0,77	disease	0,51	disease	0,61	2	neutral	0,98	neutral	0,21	deleterious	2	deleterious	0,78	low_impact	-2,31	medium_impact	0,12	high_impact	2,19	0,26	0,8	24,21	8,33	N	0,36	N	0,96	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8919	8919	A	C	MI.837	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	393	131	Q	H	caA/caC	5,68	1	0	probably_damaging	1	neutral	0,05	neutral	4,3	neutral	-1,33	deleterious	-3,38	medium_impact	2,04	neutral	0,81	damaging	0,16	deleterious	3,42	23	0,64	0,7	disease	0,64	disease	0,52	neutral	0,46	neutral	0,49	0	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	-0,43	medium_impact	0,65	0,57	0,9	44,69	8,63	N	0,49	N	0,97	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14772	14772	C	A	MI.8370	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	26	9	P	H	cCc/cAc	4,31	0,99	0	probably_damaging	1	neutral	0,57	neutral	4,48	neutral	-2,85	deleterious	-4,94	high_impact	4,16	neutral	0,9	damaging	0,09	deleterious	3,6	23,2	0,09	0,35	disease	0,66	disease	0,8	disease	0,66	disease	0,7	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,29	high_impact	2,58	0,17	0,8	24,21	8,33	N	0,46	N	0,71	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14772	14772	C	T	MI.8371	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	26	9	P	L	cCc/cTc	4,31	0,99	0	probably_damaging	1	neutral	0,67	neutral	4,52	neutral	-1,62	deleterious	-5,5	high_impact	3,81	neutral	0,94	damaging	0,13	deleterious	3,83	23,4	0,08	0,35	neutral	0,46	disease	0,76	disease	0,59	disease	0,61	2	deleterious	0,99	neutral	0,34	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	0,39	high_impact	2,27	0,63	0,8	24,21	8,33	N	0,43	N	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14772	14772	C	G	MI.8372	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	26	9	P	R	cCc/cGc	4,31	0,99	0	probably_damaging	1	neutral	0,36	neutral	4,55	neutral	-1,34	deleterious	-4,92	high_impact	3,77	neutral	0,93	damaging	0,08	deleterious	3,18	22,7	0,07	0,35	neutral	0,5	disease	0,84	disease	0,69	disease	0,74	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,09	high_impact	2,23	0,19	0,8	24,21	8,33	N	0,46	N	0,81	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14774	14774	C	G	MI.8373	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	28	10	L	V	Cta/Gta	-6,47	0	0	possibly_damaging	0,84	neutral	0,58	neutral	4,5	neutral	-0,92	neutral	-0,9	low_impact	1,78	neutral	0,96	damaging	0,14	neutral	1,33	12,42	0,24	0,45	neutral	0,38	disease	0,56	neutral	0,29	neutral	0,46	1	neutral	0,82	neutral	0,37	neutral	-3	deleterious	0,65	low_impact	-1,4	medium_impact	0,3	medium_impact	0,42	0,57	0,8	21,05	43,58	N	0,23	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14774	14774	C	A	MI.8374	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	28	10	L	M	Cta/Ata	-6,47	0	0	probably_damaging	0,99	neutral	0,26	neutral	4,4	neutral	-2,36	neutral	-0,74	low_impact	1,94	neutral	0,95	damaging	0,12	deleterious	1,86	15,35	0,28	0,45	disease	0,58	disease	0,52	neutral	0,33	neutral	0,48	0	deleterious	0,99	neutral	0,14	neutral	-2	deleterious	0,75	low_impact	-2,59	medium_impact	-0,02	medium_impact	0,57	0,54	0,8	21,05	43,58	N	0,36	N	0,62	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14775	14775	T	C	MI.8375	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	29	10	L	P	cTa/cCa	-1,42	0	0	probably_damaging	1	neutral	0,36	neutral	4,35	deleterious	-4,06	deleterious	-3,32	medium_impact	3,4	neutral	0,95	damaging	0,06	deleterious	3,48	23,1	0,01	0,35	disease	0,85	disease	0,84	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,9	low_impact	-3,53	medium_impact	0,09	medium_impact	1,89	0,2	0,8	21,05	43,58	N	0,35	N	0,95	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14775	14775	T	A	MI.8376	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	29	10	L	Q	cTa/cAa	-1,42	0	0	probably_damaging	0,99	neutral	0,42	neutral	4,36	deleterious	-3,34	deleterious	-2,91	high_impact	4,43	neutral	0,95	damaging	0,08	deleterious	3,48	23,1	0,02	0,35	disease	0,81	disease	0,84	disease	0,64	disease	0,74	5	deleterious	0,99	neutral	0,22	deleterious	2	deleterious	0,86	low_impact	-2,59	medium_impact	0,15	high_impact	2,83	0,14	0,8	21,05	43,58	N	0,43	N	0,92	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14775	14775	T	G	MI.8377	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	29	10	L	R	cTa/cGa	-1,42	0	0	probably_damaging	0,99	neutral	0,46	neutral	4,37	neutral	-2,99	deleterious	-2,98	high_impact	4,78	neutral	0,95	damaging	0,06	deleterious	3,56	23,1	0,01	0,35	disease	0,8	disease	0,9	disease	0,75	disease	0,84	7	deleterious	0,99	neutral	0,24	deleterious	2	deleterious	0,9	low_impact	-2,59	medium_impact	0,18	high_impact	3,15	0,02	0,8	21,05	43,58	P	0,73	P	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14777	14777	A	T	MI.8378	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	31	11	M	L	Ata/Tta	-1,88	0	0	benign	0	neutral	0,81	neutral	4,85	neutral	1,26	neutral	0,18	neutral_impact	-1,14	neutral	0,98	neutral	0,86	neutral	-1,37	0	0,16	0,45	neutral	0,16	neutral	0,15	neutral	0,21	neutral	0,26	5	neutral	0,18	deleterious	0,91	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,56	low_impact	-2,23	0,31	0,8	18,16	13,84	N	0,4	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14777	14777	A	G	MI.8379	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	31	11	M	V	Ata/Gta	-1,88	0	0	benign	0	neutral	0,54	neutral	4,77	neutral	0,92	neutral	-0,72	low_impact	1,08	neutral	0,98	neutral	0,79	neutral	-0,36	0,48	0,19	0,45	neutral	0,21	neutral	0,49	neutral	0,29	neutral	0,49	0	neutral	0,46	deleterious	0,77	neutral	-6	neutral	0,16	high_impact	2,07	medium_impact	0,26	medium_impact	-0,21	0,4	0,8	18,16	13,84	N	0,33	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8919	8919	A	T	MI.838	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	393	131	Q	H	caA/caT	5,68	1	0	probably_damaging	1	neutral	0,05	neutral	4,3	neutral	-1,33	deleterious	-3,38	medium_impact	2,04	neutral	0,81	damaging	0,16	deleterious	3,58	23,2	0,64	0,7	disease	0,64	disease	0,52	neutral	0,46	neutral	0,49	0	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	-0,43	medium_impact	0,65	0,57	0,9	44,69	8,63	N	0,49	N	0,97	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14777	14777	A	C	MI.8380	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	31	11	M	L	Ata/Cta	-1,88	0	0	benign	0	neutral	0,81	neutral	4,85	neutral	1,26	neutral	0,18	neutral_impact	-1,14	neutral	0,98	neutral	0,86	neutral	-1,47	0	0,16	0,45	neutral	0,16	neutral	0,15	neutral	0,21	neutral	0,26	5	neutral	0,18	deleterious	0,91	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,56	low_impact	-2,23	0,31	0,8	18,16	13,84	N	0,39	N	0,09	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14778	14778	T	A	MI.8381	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	32	11	M	K	aTa/aAa	-3,94	0	0	benign	0,04	neutral	1	neutral	4,64	neutral	-0,82	deleterious	-2,53	medium_impact	2,39	neutral	0,94	neutral	0,54	deleterious	1,96	15,95	0,02	0,35	neutral	0,32	disease	0,74	disease	0,62	disease	0,74	5	neutral	0,04	deleterious	0,98	neutral	-3	neutral	0,25	medium_impact	0,56	high_impact	1,85	medium_impact	0,98	0,24	0,8	18,16	13,84	N	0,2	N	0,71	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14778	14778	T	C	MI.8382	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	32	11	M	T	aTa/aCa	-3,94	0	0	benign	0,03	neutral	0,72	neutral	4,69	neutral	0,04	neutral	-1,97	low_impact	1,04	neutral	0,99	neutral	0,93	deleterious	0,85	9,79	0,06	0,35	neutral	0,3	disease	0,53	neutral	0,46	neutral	0,49	0	neutral	0,22	deleterious	0,85	neutral	-6	neutral	0,2	medium_impact	0,68	medium_impact	0,44	medium_impact	-0,25	0,19	0,8	18,16	13,84	N	0,32	N	0,49	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14779	14779	A	C	MI.8383	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	33	11	M	I	atA/atC	2,48	0,05	0	benign	0	neutral	0,44	neutral	4,74	neutral	0,54	neutral	-0,35	neutral_impact	-0,24	neutral	0,97	neutral	0,87	neutral	-0,64	0,1	0,18	0,45	neutral	0,19	neutral	0,3	neutral	0,21	neutral	0,44	1	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,15	high_impact	2,07	medium_impact	0,17	low_impact	-1,41	0,44	0,8	18,16	13,84	N	0,46	N	0,04	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14779	14779	A	T	MI.8384	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	33	11	M	I	atA/atT	2,48	0,05	0	benign	0	neutral	0,44	neutral	4,74	neutral	0,54	neutral	-0,35	neutral_impact	-0,24	neutral	0,97	neutral	0,87	neutral	-0,56	0,16	0,18	0,45	neutral	0,19	neutral	0,3	neutral	0,21	neutral	0,44	1	neutral	0,55	deleterious	0,72	neutral	-6	neutral	0,15	high_impact	2,07	medium_impact	0,17	low_impact	-1,41	0,44	0,8	18,16	13,84	N	0,46	N	0,04	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14780	14780	A	C	MI.8385	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	34	12	K	Q	Aaa/Caa	-1,65	0	0	probably_damaging	0,94	neutral	0,37	neutral	4,52	neutral	-1,79	neutral	-2,25	medium_impact	3,5	neutral	0,94	damaging	0,14	neutral	1,38	12,68	0,25	0,45	neutral	0,44	disease	0,79	neutral	0,47	disease	0,62	2	neutral	0,94	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-1,85	medium_impact	0,1	medium_impact	1,98	0,39	0,8	57,89	8,54	N	0,32	N	0,93	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14780	14780	A	G	MI.8386	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	34	12	K	E	Aaa/Gaa	-1,65	0	0	probably_damaging	0,94	neutral	0,41	neutral	4,56	neutral	-0,4	neutral	-2,25	high_impact	3,75	neutral	0,79	damaging	0,13	deleterious	2	16,19	0,13	0,4	neutral	0,36	disease	0,82	disease	0,6	disease	0,69	4	neutral	0,94	neutral	0,24	deleterious	2	deleterious	0,78	low_impact	-1,85	medium_impact	0,14	high_impact	2,21	0,48	0,8	57,89	8,54	N	0,27	N	0,95	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14781	14781	A	T	MI.8387	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	35	12	K	M	aAa/aTa	5,46	1	0	probably_damaging	0,99	neutral	0,26	neutral	4,45	deleterious	-4,22	deleterious	-3,43	high_impact	4,03	neutral	0,91	damaging	0,15	deleterious	3,26	22,8	0,06	0,35	disease	0,74	disease	0,79	neutral	0,49	disease	0,65	3	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,78	low_impact	-2,59	medium_impact	-0,02	high_impact	2,47	0,18	0,8	57,89	8,54	N	0,54	P	0,67	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14781	14781	A	C	MI.8388	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	35	12	K	T	aAa/aCa	5,46	1	0	probably_damaging	0,98	neutral	0,47	neutral	4,51	neutral	-1,63	deleterious	-3,37	high_impact	3,85	neutral	0,91	damaging	0,14	neutral	1,7	14,4	0,04	0,35	neutral	0,46	disease	0,8	neutral	0,5	disease	0,66	3	neutral	0,98	neutral	0,25	deleterious	2	deleterious	0,8	low_impact	-2,31	medium_impact	0,19	high_impact	2,3	0,2	0,8	57,89	8,54	N	0,53	P	0,88	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14782	14782	A	T	MI.8389	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	36	12	K	N	aaA/aaT	6,61	1	0	probably_damaging	0,99	neutral	0,39	neutral	4,52	neutral	-0,72	deleterious	-2,65	medium_impact	2,56	neutral	0,91	damaging	0,14	deleterious	1,91	15,64	0,31	0,45	neutral	0,4	disease	0,76	neutral	0,49	disease	0,56	1	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,78	low_impact	-2,59	medium_impact	0,12	medium_impact	1,13	0,47	0,8	57,89	8,54	N	0,52	P	0,84	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8920	8920	G	A	MI.839	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	394	132	G	S	Ggc/Agc	2,67	1	0	probably_damaging	1	neutral	0,07	neutral	3,52	neutral	-2,98	deleterious	-5,42	medium_impact	3,17	neutral	0,61	neutral	0,5	deleterious	4,19	23,9	0,41	0,65	disease	0,83	disease	0,75	disease	0,61	disease	0,54	1	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,82	low_impact	-3,6	medium_impact	-0,34	medium_impact	1,62	0,79	0,9	48,23	8,73	N	0,41	N	0,98	disease_causing	1	0,2	rs28406348	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14782	14782	A	C	MI.8390	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	36	12	K	N	aaA/aaC	6,61	1	0	probably_damaging	0,99	neutral	0,39	neutral	4,52	neutral	-0,72	deleterious	-2,65	medium_impact	2,56	neutral	0,91	damaging	0,14	deleterious	1,85	15,26	0,31	0,45	neutral	0,4	disease	0,76	neutral	0,49	disease	0,56	1	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,78	low_impact	-2,59	medium_impact	0,12	medium_impact	1,13	0,47	0,8	57,89	8,54	N	0,5	N	0,84	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14783	14783	T	G	MI.8391	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	37	13	L	V	Tta/Gta	6,84	1	0,71	probably_damaging	0,98	neutral	0,64	neutral	4,61	neutral	-0,67	neutral	0,31	low_impact	1,36	neutral	0,96	neutral	0,78	neutral	1,62	13,94	0,27	0,45	neutral	0,29	neutral	0,4	neutral	0,21	neutral	0,42	2	deleterious	0,98	neutral	0,33	neutral	-2	deleterious	0,69	low_impact	-2,31	medium_impact	0,36	medium_impact	0,04	0,71	0,85	22,37	58,02	N	0,5	N	0,25	polymorphism	1	0,01	rs193302982	Likely pathogenic	Familial_cancer_of_breast	RCV000128803.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	14783	14783	T	A	MI.8392	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	37	13	L	M	Tta/Ata	6,84	1	0,71	probably_damaging	1	neutral	0,23	neutral	4,53	neutral	-1,63	neutral	-0,48	neutral_impact	0,19	neutral	0,94	neutral	0,91	deleterious	2,24	17,76	0,24	0,45	neutral	0,47	neutral	0,29	neutral	0,18	neutral	0,4	2	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,71	low_impact	-3,53	medium_impact	-0,06	low_impact	-1,02	0,56	0,8	22,37	58,02	P	0,58	P	0,04	polymorphism	1	0,02	rs193302982	Likely pathogenic	Familial_cancer_of_breast	RCV000128803.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	14784	14784	T	C	MI.8393	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	38	13	L	S	tTa/tCa	3,63	1	0	probably_damaging	0,99	neutral	0,54	neutral	4,48	neutral	-2,26	neutral	-2,36	medium_impact	2,14	neutral	0,94	neutral	0,64	deleterious	3,35	22,9	0,03	0,35	disease	0,59	disease	0,54	disease	0,52	disease	0,56	1	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,78	low_impact	-2,59	medium_impact	0,26	medium_impact	0,75	0,17	0,8	22,37	58,02	N	0,4	N	0,63	polymorphism	1	0,08	rs527236163	Likely pathogenic	Neoplasm_of_ovary	RCV000133405.1	Gene:MedGen:OMIM:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	14784	14784	T	G	MI.8394	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	38	13	L	W	tTa/tGa	3,63	1	0	probably_damaging	1	neutral	0,18	neutral	4,43	deleterious	-4,71	deleterious	-2,92	medium_impact	2,48	neutral	0,94	neutral	0,47	deleterious	3,54	23,1	0,04	0,35	disease	0,85	disease	0,65	disease	0,54	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,83	low_impact	-3,53	medium_impact	-0,14	medium_impact	1,06	0,2	0,8	22,37	58,02	N	0,53	P	0,76	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14785	14785	A	C	MI.8395	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	39	13	L	F	ttA/ttC	1,79	0,98	0	probably_damaging	0,99	neutral	0,75	neutral	4,49	neutral	-1,91	neutral	-1,3	low_impact	1,45	neutral	0,94	neutral	0,67	deleterious	2,97	22,1	0,19	0,45	disease	0,57	disease	0,5	disease	0,51	disease	0,52	0	deleterious	0,99	neutral	0,38	neutral	-2	deleterious	0,77	low_impact	-2,59	medium_impact	0,48	medium_impact	0,12	0,74	0,85	22,37	58,02	N	0,39	N	0,33	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14785	14785	A	T	MI.8396	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	39	13	L	F	ttA/ttT	1,79	0,98	0	probably_damaging	0,99	neutral	0,75	neutral	4,49	neutral	-1,91	neutral	-1,3	low_impact	1,45	neutral	0,94	neutral	0,67	deleterious	3,08	22,5	0,19	0,45	disease	0,57	disease	0,5	disease	0,51	disease	0,52	0	deleterious	0,99	neutral	0,38	neutral	-2	deleterious	0,77	low_impact	-2,59	medium_impact	0,48	medium_impact	0,12	0,74	0,85	22,37	58,02	N	0,4	N	0,33	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14786	14786	A	G	MI.8397	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	40	14	I	V	Att/Gtt	-1,65	0	0	benign	0	neutral	0,74	neutral	4,7	neutral	0,5	neutral	-0,1	neutral_impact	0,4	neutral	0,98	neutral	0,91	neutral	-0,52	0,2	0,49	0,55	neutral	0,16	neutral	0,16	neutral	0,24	neutral	0,27	5	neutral	0,26	deleterious	0,87	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,47	medium_impact	-0,83	0,32	0,8	12,11	20,15	N	0,36	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14786	14786	A	T	MI.8398	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	40	14	I	F	Att/Ttt	-1,65	0	0	benign	0,12	neutral	0,65	neutral	4,59	neutral	-0,84	neutral	-1,85	medium_impact	2,06	neutral	0,95	damaging	0,15	neutral	1,64	14,08	0,09	0,35	disease	0,71	disease	0,67	neutral	0,33	neutral	0,5	0	neutral	0,24	deleterious	0,77	neutral	-3	deleterious	0,45	medium_impact	0,08	medium_impact	0,37	medium_impact	0,68	0,56	0,8	12,11	20,15	N	0,22	N	0,95	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14786	14786	A	C	MI.8399	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	40	14	I	L	Att/Ctt	-1,65	0	0	benign	0,01	neutral	1	neutral	4,7	neutral	0,4	neutral	-0,77	low_impact	1,14	neutral	0,97	neutral	0,69	deleterious	0,6	8,18	0,22	0,45	neutral	0,28	disease	0,51	neutral	0,24	neutral	0,46	1	neutral	0,01	deleterious	1	neutral	-6	neutral	0,17	medium_impact	1,13	high_impact	1,85	medium_impact	-0,16	0,62	0,8	12,11	20,15	N	0,29	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8563	8563	A	C	MI.84	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	37	13	T	P	Aca/Cca	-8,89	0	0,12	probably_damaging	1	deleterious	0,02	neutral	4,5	neutral	-2,58	deleterious	-3,81	medium_impact	2,1	neutral	0,73	neutral	0,33	deleterious	3,31	22,9	0,19	0,65	disease	0,81	disease	0,9	disease	0,72	disease	0,82	6	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,82	low_impact	-3,6	medium_impact	-0,66	medium_impact	0,7	0,56	0,9	15,49	16,77	N	0,26	N	0,96	polymorphism	1	0,18	rs386829041	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8920	8920	G	C	MI.840	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	394	132	G	R	Ggc/Cgc	2,67	1	0	probably_damaging	1	deleterious	0	neutral	3,47	deleterious	-3,62	deleterious	-7,28	high_impact	4,03	damaging	0,55	neutral	0,31	deleterious	3,97	23,6	0,33	0,65	disease	0,88	disease	0,88	disease	0,73	disease	0,68	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,36	0,87	0,9	48,23	8,73	N	0,43	N	0,98	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14787	14787	T	G	MI.8400	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	41	14	I	S	aTt/aGt	-0,04	0	0	benign	0,23	neutral	0,78	neutral	4,56	neutral	-1,21	neutral	-2,12	medium_impact	3,26	neutral	0,94	damaging	0,15	deleterious	2,25	17,81	0,02	0,35	disease	0,77	disease	0,79	disease	0,55	disease	0,74	5	neutral	0,14	deleterious	0,78	neutral	-3	deleterious	0,47	medium_impact	-0,24	medium_impact	0,52	medium_impact	1,77	0,23	0,8	12,11	20,15	N	0,2	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14787	14787	T	A	MI.8401	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	41	14	I	N	aTt/aAt	-0,04	0	0	possibly_damaging	0,57	neutral	0,67	neutral	4,53	neutral	-2,38	deleterious	-3,07	high_impact	4,24	neutral	0,93	damaging	0,16	deleterious	2,51	19,56	0,05	0,35	disease	0,87	disease	0,8	disease	0,58	disease	0,78	6	neutral	0,49	deleterious	0,55	deleterious	1	deleterious	0,74	medium_impact	-0,85	medium_impact	0,39	high_impact	2,66	0,23	0,8	12,11	20,15	N	0,28	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14787	14787	T	C	MI.8402	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	41	14	I	T	aTt/aCt	-0,04	0	0	benign	0,08	neutral	0,66	neutral	4,58	neutral	-0,9	neutral	-1,76	medium_impact	2,69	neutral	0,94	damaging	0,16	neutral	1,39	12,72	0,04	0,35	disease	0,66	disease	0,61	neutral	0,39	disease	0,52	0	neutral	0,25	deleterious	0,79	neutral	-3	neutral	0,33	medium_impact	0,26	medium_impact	0,38	medium_impact	1,25	0,3	0,8	12,11	20,15	N	0,21	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14788	14788	T	A	MI.8403	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	42	14	I	M	atT/atA	2,48	0,04	0	benign	0,23	neutral	0,29	neutral	4,58	neutral	-0,96	neutral	-1,1	low_impact	1,64	neutral	0,97	neutral	0,76	deleterious	0,51	7,53	0,21	0,45	disease	0,59	neutral	0,45	neutral	0,25	disease	0,61	2	neutral	0,65	deleterious	0,53	neutral	-6	neutral	0,32	medium_impact	-0,24	medium_impact	0,01	medium_impact	0,3	0,57	0,8	12,11	20,15	N	0,44	N	0,7	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14788	14788	T	G	MI.8404	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	42	14	I	M	atT/atG	2,48	0,04	0	benign	0,23	neutral	0,29	neutral	4,58	neutral	-0,96	neutral	-1,1	low_impact	1,64	neutral	0,97	neutral	0,76	deleterious	0,27	5,37	0,21	0,45	disease	0,59	neutral	0,45	neutral	0,25	disease	0,61	2	neutral	0,65	deleterious	0,53	neutral	-6	neutral	0,32	medium_impact	-0,24	medium_impact	0,01	medium_impact	0,3	0,57	0,8	12,11	20,15	N	0,44	N	0,7	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14789	14789	A	G	MI.8405	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	43	15	N	D	Aac/Gac	-6,24	0	0	benign	0,04	neutral	0,36	neutral	4,58	neutral	-1,04	deleterious	-3,05	high_impact	3,66	neutral	0,92	neutral	0,34	deleterious	1,8	15	0,46	0,55	disease	0,52	disease	0,7	disease	0,62	disease	0,66	3	neutral	0,61	deleterious	0,66	neutral	-2	neutral	0,29	medium_impact	0,56	medium_impact	0,09	high_impact	2,13	0,23	0,8	57,37	8,49	N	0,32	N	0,95	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14789	14789	A	C	MI.8406	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	43	15	N	H	Aac/Cac	-6,24	0	0	possibly_damaging	0,53	neutral	0,57	neutral	4,54	neutral	-1,89	deleterious	-3,05	high_impact	4,07	neutral	0,94	damaging	0,19	deleterious	2,53	19,64	0,21	0,45	disease	0,72	disease	0,77	disease	0,68	disease	0,7	4	neutral	0,48	deleterious	0,52	deleterious	1	deleterious	0,69	medium_impact	-0,78	medium_impact	0,29	high_impact	2,5	0,25	0,8	57,37	8,49	N	0,24	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14789	14789	A	T	MI.8407	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	43	15	N	Y	Aac/Tac	-6,24	0	0	possibly_damaging	0,65	neutral	1	neutral	4,55	neutral	-2,24	deleterious	-4,87	medium_impact	3,48	neutral	0,97	neutral	0,35	deleterious	3,23	22,8	0,05	0,35	neutral	0,45	disease	0,82	disease	0,63	disease	0,69	4	neutral	0,65	deleterious	0,68	NA	0	deleterious	0,71	medium_impact	-0,98	high_impact	1,85	medium_impact	1,97	0,24	0,8	57,37	8,49	N	0,23	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14790	14790	A	T	MI.8408	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	44	15	N	I	aAc/aTc	6,61	1	0	possibly_damaging	0,57	neutral	0,45	neutral	4,53	neutral	-2,39	deleterious	-5,49	high_impact	4,21	neutral	0,94	neutral	0,41	deleterious	3,45	23	0,05	0,35	disease	0,74	disease	0,85	disease	0,62	disease	0,71	4	neutral	0,58	neutral	0,44	deleterious	1	deleterious	0,66	medium_impact	-0,85	medium_impact	0,18	high_impact	2,63	0,17	0,8	57,37	8,49	P	0,63	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14790	14790	A	G	MI.8409	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	44	15	N	S	aAc/aGc	6,61	1	0	benign	0	neutral	0,59	neutral	4,62	neutral	-0,6	deleterious	-3,03	high_impact	3,56	neutral	0,94	neutral	0,44	neutral	1,03	10,85	0,39	0,5	disease	0,52	disease	0,73	neutral	0,48	neutral	0,49	0	neutral	0,41	deleterious	0,8	neutral	-2	neutral	0,27	high_impact	2,07	medium_impact	0,31	high_impact	2,04	0,32	0,8	57,37	8,49	N	0,52	P	0,86	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8920	8920	G	T	MI.841	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	394	132	G	C	Ggc/Tgc	2,67	1	0	probably_damaging	1	deleterious	0	neutral	3,43	deleterious	-6	deleterious	-8,21	high_impact	4,58	damaging	0,57	neutral	0,29	deleterious	4,13	23,8	0,24	0,65	disease	0,98	disease	0,86	disease	0,69	disease	0,74	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,6	low_impact	-1,4	high_impact	2,83	0,53	0,9	48,23	8,73	N	0,46	N	1	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14790	14790	A	C	MI.8410	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	44	15	N	T	aAc/aCc	6,61	1	0	benign	0,04	neutral	0,53	neutral	4,59	neutral	-0,91	deleterious	-3,64	medium_impact	3,41	neutral	0,94	neutral	0,4	neutral	1,39	12,76	0,16	0,45	disease	0,59	disease	0,79	disease	0,64	disease	0,69	4	neutral	0,42	deleterious	0,75	neutral	-3	neutral	0,34	medium_impact	0,56	medium_impact	0,25	medium_impact	1,9	0,26	0,8	57,37	8,49	N	0,51	P	0,94	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14791	14791	C	A	MI.8411	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	45	15	N	K	aaC/aaA	5,46	1	0	benign	0,15	neutral	0,53	neutral	4,66	neutral	-0,05	deleterious	-3,66	medium_impact	3,41	neutral	0,94	damaging	0,27	deleterious	2,58	19,96	0,22	0,45	neutral	0,38	disease	0,81	disease	0,64	disease	0,69	4	neutral	0,37	deleterious	0,69	neutral	-3	deleterious	0,52	medium_impact	-0,03	medium_impact	0,25	medium_impact	1,9	0,46	0,8	57,37	8,49	N	0,47	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14791	14791	C	G	MI.8412	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	45	15	N	K	aaC/aaG	5,46	1	0	benign	0,15	neutral	0,53	neutral	4,66	neutral	-0,05	deleterious	-3,66	medium_impact	3,41	neutral	0,94	damaging	0,27	deleterious	2,14	17,09	0,22	0,45	neutral	0,38	disease	0,81	disease	0,64	disease	0,69	4	neutral	0,37	deleterious	0,69	neutral	-3	deleterious	0,52	medium_impact	-0,03	medium_impact	0,25	medium_impact	1,9	0,46	0,8	57,37	8,49	N	0,47	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14792	14792	C	G	MI.8413	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	46	16	H	D	Cac/Gac	-2,11	0	0	benign	0,21	neutral	0,69	neutral	4,75	neutral	0,07	neutral	-0,02	neutral_impact	-0,25	neutral	0,96	neutral	0,76	deleterious	-0,05	2,13	0,05	0,35	neutral	0,24	neutral	0,19	neutral	0,42	neutral	0,36	3	neutral	0,2	deleterious	0,74	neutral	-6	neutral	0,25	medium_impact	-0,19	medium_impact	0,41	low_impact	-1,42	0,39	0,8	28,68	20,84	N	0,3	N	0,71	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14792	14792	C	T	MI.8414	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	46	16	H	Y	Cac/Tac	-2,11	0	0	benign	0,27	neutral	0,16	neutral	4,64	neutral	-1,77	neutral	-1,92	medium_impact	1,98	neutral	0,98	neutral	0,72	neutral	1,67	14,22	0,18	0,45	neutral	0,29	neutral	0,45	neutral	0,36	neutral	0,48	0	neutral	0,81	neutral	0,45	neutral	-3	neutral	0,36	medium_impact	-0,33	medium_impact	-0,17	medium_impact	0,6	0,28	0,8	28,68	20,84	N	0,51	P	0,72	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14792	14792	C	A	MI.8415	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	46	16	H	N	Cac/Aac	-2,11	0	0	benign	0,11	neutral	0,67	neutral	4,75	neutral	0,21	neutral	0,54	neutral_impact	-0,73	neutral	0,95	neutral	0,93	neutral	-0,62	0,11	0,3	0,45	neutral	0,14	neutral	0,14	neutral	0,25	neutral	0,23	5	neutral	0,22	deleterious	0,78	neutral	-6	neutral	0,17	medium_impact	0,12	medium_impact	0,39	low_impact	-1,86	0,31	0,8	28,68	20,84	N	0,3	N	0,06	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14793	14793	A	C	MI.8416	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	47	16	H	P	cAc/cCc	-0,96	0	0,07	benign	0,39	neutral	0,34	neutral	4,65	neutral	-1,61	neutral	-2,06	medium_impact	2,82	neutral	0,98	neutral	0,4	neutral	1,27	12,1	0,04	0,35	neutral	0,44	disease	0,77	disease	0,7	disease	0,78	6	neutral	0,6	deleterious	0,48	neutral	-3	deleterious	0,56	medium_impact	-0,55	medium_impact	0,07	medium_impact	1,37	0,18	0,8	28,68	20,84	N	0,36	N	0,93	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14793	14793	A	T	MI.8417	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	47	16	H	L	cAc/cTc	-0,96	0	0,07	benign	0,12	neutral	0,46	neutral	4,67	neutral	-0,95	deleterious	-3,02	medium_impact	2,67	neutral	0,95	neutral	0,52	deleterious	1,9	15,58	0,06	0,35	neutral	0,35	disease	0,57	neutral	0,48	neutral	0,49	0	neutral	0,46	deleterious	0,67	neutral	-3	neutral	0,28	medium_impact	0,08	medium_impact	0,18	medium_impact	1,23	0,17	0,8	28,68	20,84	N	0,34	N	0,82	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14793	14793	A	G	MI.8418	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	47	16	H	R	cAc/cGc	-0,96	0	0,07	benign	0	neutral	0,55	neutral	4,71	neutral	-0,02	neutral	-1,39	medium_impact	2,33	neutral	0,97	neutral	0,64	neutral	1,01	10,71	0,13	0,4	neutral	0,23	disease	0,57	disease	0,55	disease	0,66	3	neutral	0,44	deleterious	0,78	neutral	-3	neutral	0,17	high_impact	2,07	medium_impact	0,27	medium_impact	0,92	0,31	0,8	28,68	20,84	N	0,25	N	0,11	polymorphism	1	0,02	rs2853504	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14794	14794	C	A	MI.8419	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	48	16	H	Q	caC/caA	1,79	0	0	benign	0,12	neutral	0,6	neutral	4,72	neutral	0,09	neutral	-1,04	low_impact	1,92	neutral	0,96	neutral	0,67	deleterious	0,76	9,19	0,19	0,45	neutral	0,18	neutral	0,39	neutral	0,36	neutral	0,45	1	neutral	0,3	deleterious	0,74	neutral	-6	neutral	0,24	medium_impact	0,08	medium_impact	0,32	medium_impact	0,55	0,37	0,8	28,68	20,84	N	0,32	N	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8921	8921	G	A	MI.842	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	395	132	G	D	gGc/gAc	7,53	1	0	probably_damaging	1	deleterious	0,02	neutral	3,49	deleterious	-3,17	deleterious	-6,37	high_impact	4,03	neutral	0,65	neutral	0,37	deleterious	3,87	23,5	0,31	0,65	disease	0,57	disease	0,86	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,8	low_impact	-3,6	medium_impact	-0,66	high_impact	2,36	0,39	0,9	48,23	8,73	P	0,5	N	1	disease_causing	1	0,22	rs2298008	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14794	14794	C	G	MI.8420	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	48	16	H	Q	caC/caG	1,79	0	0	benign	0,12	neutral	0,6	neutral	4,72	neutral	0,09	neutral	-1,04	low_impact	1,92	neutral	0,96	neutral	0,67	deleterious	0,54	7,7	0,19	0,45	neutral	0,18	neutral	0,39	neutral	0,36	neutral	0,45	1	neutral	0,3	deleterious	0,74	neutral	-6	neutral	0,24	medium_impact	0,08	medium_impact	0,32	medium_impact	0,55	0,37	0,8	28,68	20,84	N	0,31	N	0,6	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14795	14795	T	G	MI.8421	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	49	17	S	A	Tca/Gca	-1,88	0	0	possibly_damaging	0,76	neutral	0,55	neutral	4,66	neutral	-0,33	neutral	-0,45	neutral_impact	0,34	neutral	0,98	neutral	0,8	deleterious	-0,07	2,01	0,24	0,45	neutral	0,17	neutral	0,07	neutral	0,22	neutral	0,31	4	neutral	0,72	neutral	0,4	neutral	-3	neutral	0,4	low_impact	-1,2	medium_impact	0,27	medium_impact	-0,89	0,42	0,8	10	37,24	N	0,42	N	0,18	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14795	14795	T	A	MI.8422	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	49	17	S	T	Tca/Aca	-1,88	0	0	possibly_damaging	0,63	neutral	0,42	neutral	4,63	neutral	-0,38	neutral	-1,27	medium_impact	1,99	neutral	0,97	damaging	0,22	deleterious	0,76	9,21	0,19	0,45	neutral	0,33	neutral	0,46	neutral	0,27	neutral	0,47	1	neutral	0,65	neutral	0,4	NA	0	deleterious	0,53	medium_impact	-0,95	medium_impact	0,15	medium_impact	0,61	0,49	0,8	10	37,24	N	0,34	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14795	14795	T	C	MI.8423	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	49	17	S	P	Tca/Cca	-1,88	0	0	probably_damaging	0,93	neutral	0,23	neutral	4,56	neutral	-1,73	neutral	-2,38	medium_impact	3,23	neutral	0,95	damaging	0,09	deleterious	1,98	16,06	0,05	0,35	neutral	0,38	disease	0,81	disease	0,71	disease	0,74	5	neutral	0,95	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-1,78	medium_impact	-0,06	medium_impact	1,74	0,28	0,8	10	37,24	N	0,35	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14796	14796	C	T	MI.8424	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	50	17	S	L	tCa/tTa	0,41	0	0	probably_damaging	0,95	neutral	0,68	neutral	4,6	neutral	-1	deleterious	-2,72	medium_impact	2,98	neutral	0,95	damaging	0,11	deleterious	2,69	20,8	0,05	0,35	neutral	0,3	disease	0,72	disease	0,57	disease	0,66	3	neutral	0,95	neutral	0,37	deleterious	1	deleterious	0,69	low_impact	-1,92	medium_impact	0,4	medium_impact	1,51	0,37	0,8	10	37,24	N	0,21	N	0,98	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14796	14796	C	G	MI.8425	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	50	17	S	W	tCa/tGa	0,41	0	0	probably_damaging	0,99	neutral	0,19	neutral	4,53	deleterious	-4,53	deleterious	-3,59	high_impact	4,47	neutral	0,96	damaging	0,12	deleterious	3,85	23,4	0,06	0,35	disease	0,77	disease	0,78	disease	0,64	disease	0,71	4	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	-0,12	high_impact	2,87	0,11	0,8	10	37,24	N	0,47	N	0,98	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14798	14798	T	C	MI.8426	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	52	18	F	L	Ttc/Ctc	-0,73	0	0,13	benign	0	neutral	0,66	neutral	4,8	neutral	0,58	neutral	-0,31	neutral_impact	-0,49	neutral	0,99	neutral	0,9	deleterious	0,3	5,73	0,17	0,45	neutral	0,15	neutral	0,18	neutral	0,41	neutral	0,24	5	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,38	low_impact	-1,64	0,72	0,85	17,89	26,96	N	0,34	N	0,09	polymorphism	1	0,01	rs28357681	.	.	.	.	glioblastoma	.	.	.	.	.	.	.	.	.
chrM	14798	14798	T	G	MI.8427	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	52	18	F	V	Ttc/Gtc	-0,73	0	0,13	benign	0,02	neutral	0,51	neutral	4,67	neutral	-0,03	neutral	-1,58	low_impact	1,5	neutral	0,95	neutral	0,52	neutral	1,13	11,39	0,1	0,4	neutral	0,26	disease	0,69	disease	0,54	disease	0,51	0	neutral	0,47	deleterious	0,75	neutral	-6	neutral	0,17	medium_impact	0,85	medium_impact	0,23	medium_impact	0,17	0,37	0,8	17,89	26,96	N	0,27	N	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14798	14798	T	A	MI.8428	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	52	18	F	I	Ttc/Atc	-0,73	0	0,13	benign	0	neutral	0,4	neutral	4,65	neutral	-0,06	neutral	-0,96	medium_impact	2,63	neutral	0,94	neutral	0,46	deleterious	2,43	19	0,14	0,4	neutral	0,2	disease	0,67	disease	0,52	disease	0,55	1	neutral	0,59	deleterious	0,7	neutral	-3	neutral	0,17	high_impact	2,07	medium_impact	0,13	medium_impact	1,19	0,43	0,8	17,89	26,96	N	0,34	N	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14799	14799	T	G	MI.8429	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	53	18	F	C	tTc/tGc	-1,65	0	0	possibly_damaging	0,44	neutral	0,18	neutral	4,52	neutral	-2,91	deleterious	-2,6	high_impact	4,22	neutral	0,94	neutral	0,39	deleterious	3,68	23,3	0,03	0,35	disease	0,64	disease	0,76	disease	0,71	disease	0,76	5	neutral	0,79	neutral	0,37	deleterious	1	deleterious	0,52	medium_impact	-0,63	medium_impact	-0,14	high_impact	2,64	0,23	0,8	17,89	26,96	N	0,42	N	0,83	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8921	8921	G	C	MI.843	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	395	132	G	A	gGc/gCc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	3,49	neutral	-2,68	deleterious	-5,4	high_impact	3,68	neutral	0,66	neutral	0,46	deleterious	3,1	22,5	0,44	0,65	disease	0,79	disease	0,62	disease	0,66	disease	0,58	2	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,6	low_impact	-1,4	high_impact	2,06	0,7	0,9	48,23	8,73	P	0,52	P	0,79	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14799	14799	T	A	MI.8430	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	53	18	F	Y	tTc/tAc	-1,65	0	0	benign	0,04	neutral	1	neutral	4,55	neutral	-1,64	neutral	-1,19	medium_impact	3,06	neutral	0,95	neutral	0,48	deleterious	2,31	18,25	0,14	0,4	disease	0,56	disease	0,6	disease	0,7	disease	0,74	5	neutral	0,04	deleterious	0,98	neutral	-3	neutral	0,24	medium_impact	0,56	high_impact	1,85	medium_impact	1,59	0,61	0,8	17,89	26,96	N	0,21	N	0,77	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14799	14799	T	C	MI.8431	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	53	18	F	S	tTc/tCc	-1,65	0	0	benign	0,08	neutral	0,42	neutral	4,56	neutral	-1,46	deleterious	-2,94	high_impact	3,87	neutral	0,93	neutral	0,48	deleterious	2,37	18,66	0,03	0,35	neutral	0,49	disease	0,72	disease	0,67	disease	0,71	4	neutral	0,53	deleterious	0,67	neutral	-2	neutral	0,31	medium_impact	0,26	medium_impact	0,15	high_impact	2,32	0,24	0,8	17,89	26,96	N	0,33	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14800	14800	C	A	MI.8432	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	54	18	F	L	ttC/ttA	7,3	0,95	0	benign	0	neutral	0,66	neutral	4,8	neutral	0,58	neutral	-0,31	neutral_impact	-0,49	neutral	0,99	neutral	0,9	neutral	0,92	10,2	0,17	0,45	neutral	0,15	neutral	0,18	neutral	0,41	neutral	0,24	5	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,38	low_impact	-1,64	0,72	0,85	17,89	26,96	N	0,53	P	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14800	14800	C	G	MI.8433	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	54	18	F	L	ttC/ttG	7,3	0,95	0	benign	0	neutral	0,66	neutral	4,8	neutral	0,58	neutral	-0,31	neutral_impact	-0,49	neutral	0,99	neutral	0,9	deleterious	0,58	8,03	0,17	0,45	neutral	0,15	neutral	0,18	neutral	0,41	neutral	0,24	5	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,38	low_impact	-1,64	0,72	0,85	17,89	26,96	N	0,53	P	0,09	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14801	14801	A	C	MI.8434	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	55	19	I	L	Atc/Ctc	-5,32	0	0	benign	0,01	neutral	0,88	neutral	4,69	neutral	0,1	neutral	-1,26	medium_impact	2,59	neutral	0,94	neutral	0,43	neutral	1,74	14,63	0,2	0,45	disease	0,53	disease	0,57	neutral	0,43	neutral	0,48	0	neutral	0,1	deleterious	0,94	neutral	-3	neutral	0,23	medium_impact	1,13	medium_impact	0,69	medium_impact	1,16	0,57	0,8	52,11	8,81	N	0,2	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14801	14801	A	G	MI.8435	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	55	19	I	V	Atc/Gtc	-5,32	0	0	benign	0	neutral	0,61	neutral	4,73	neutral	0,29	neutral	-0,3	low_impact	0,96	neutral	0,97	neutral	0,95	neutral	-0,3	0,66	0,36	0,5	neutral	0,28	neutral	0,09	neutral	0,25	neutral	0,28	4	neutral	0,39	deleterious	0,81	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,33	medium_impact	-0,32	0,43	0,8	52,11	8,81	N	0,42	N	0,84	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14801	14801	A	T	MI.8436	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	55	19	I	F	Atc/Ttc	-5,32	0	0	benign	0,11	neutral	0,77	neutral	4,55	neutral	-1,47	deleterious	-2,53	medium_impact	3,4	neutral	0,93	neutral	0,46	neutral	1,76	14,77	0,05	0,35	disease	0,83	disease	0,72	disease	0,52	disease	0,62	2	neutral	0,12	deleterious	0,83	neutral	-3	deleterious	0,52	medium_impact	0,12	medium_impact	0,51	medium_impact	1,89	0,57	0,8	52,11	8,81	N	0,2	N	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14802	14802	T	A	MI.8437	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	56	19	I	N	aTc/aAc	2,48	0,98	0	possibly_damaging	0,62	neutral	0,38	neutral	4,51	neutral	-2,51	deleterious	-4,27	high_impact	3,98	neutral	0,92	neutral	0,44	deleterious	2,68	20,7	0,04	0,35	disease	0,94	disease	0,77	disease	0,62	disease	0,82	6	neutral	0,67	neutral	0,38	deleterious	1	deleterious	0,72	medium_impact	-0,93	medium_impact	0,11	high_impact	2,42	0,27	0,8	52,11	8,81	N	0,55	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14802	14802	T	G	MI.8438	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	56	19	I	S	aTc/aGc	2,48	0,98	0	benign	0,24	neutral	0,65	neutral	4,56	neutral	-1,1	deleterious	-3,63	medium_impact	3,32	neutral	0,94	neutral	0,42	deleterious	2,42	18,94	0,02	0,35	disease	0,89	disease	0,8	disease	0,6	disease	0,77	5	neutral	0,24	deleterious	0,71	neutral	-3	deleterious	0,64	medium_impact	-0,26	medium_impact	0,37	medium_impact	1,82	0,21	0,8	52,11	8,81	N	0,4	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14802	14802	T	C	MI.8439	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	56	19	I	T	aTc/aCc	2,48	0,98	0	benign	0,14	neutral	0,4	neutral	4,58	neutral	-0,95	deleterious	-2,83	medium_impact	2,72	neutral	0,96	neutral	0,46	neutral	1,48	13,21	0,03	0,35	disease	0,8	disease	0,66	disease	0,52	disease	0,56	1	neutral	0,53	deleterious	0,63	neutral	-3	deleterious	0,5	medium_impact	0	medium_impact	0,13	medium_impact	1,28	0,24	0,8	52,11	8,81	N	0,45	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8921	8921	G	T	MI.844	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	395	132	G	V	gGc/gTc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	3,46	deleterious	-3,27	deleterious	-8,18	high_impact	4,58	damaging	0,54	neutral	0,38	deleterious	3,78	23,4	0,26	0,65	disease	0,92	disease	0,85	disease	0,68	disease	0,7	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,6	low_impact	-1,4	high_impact	2,83	0,5	0,9	48,23	8,73	P	0,57	P	0,99	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14803	14803	C	A	MI.8440	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	57	19	I	M	atC/atA	7,3	1	0	benign	0,01	neutral	0,21	neutral	4,56	neutral	-1,14	neutral	-1,73	medium_impact	2,92	neutral	0,87	neutral	0,56	deleterious	1,9	15,56	0,11	0,4	disease	0,79	disease	0,55	neutral	0,43	disease	0,56	1	neutral	0,79	deleterious	0,6	neutral	-3	neutral	0,26	medium_impact	1,13	medium_impact	-0,09	medium_impact	1,46	0,58	0,8	52,11	8,81	P	0,62	P	0,82	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14803	14803	C	G	MI.8441	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	57	19	I	M	atC/atG	7,3	1	0	benign	0,01	neutral	0,21	neutral	4,56	neutral	-1,14	neutral	-1,73	medium_impact	2,92	neutral	0,87	neutral	0,56	neutral	1,43	12,93	0,11	0,4	disease	0,79	disease	0,55	neutral	0,43	disease	0,56	1	neutral	0,79	deleterious	0,6	neutral	-3	neutral	0,26	medium_impact	1,13	medium_impact	-0,09	medium_impact	1,46	0,58	0,8	52,11	8,81	P	0,62	P	0,82	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14804	14804	G	T	MI.8442	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	58	20	D	Y	Gac/Tac	-3,94	0	0	probably_damaging	1	neutral	1	neutral	4,5	neutral	-2,74	deleterious	-5,8	high_impact	4,22	neutral	0,81	neutral	0,44	deleterious	3,67	23,3	0,03	0,35	disease	0,75	disease	0,9	disease	0,66	disease	0,73	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,87	low_impact	-3,53	high_impact	1,85	high_impact	2,64	0,16	0,8	57,63	8,6	N	0,29	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14804	14804	G	C	MI.8443	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	58	20	D	H	Gac/Cac	-3,94	0	0	probably_damaging	1	neutral	0,54	neutral	4,53	neutral	-1,99	deleterious	-4,5	high_impact	4,22	neutral	0,8	neutral	0,34	deleterious	3,35	22,9	0,04	0,35	disease	0,66	disease	0,83	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,26	high_impact	2,64	0,5	0,8	57,63	8,6	N	0,27	N	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14804	14804	G	A	MI.8444	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	58	20	D	N	Gac/Aac	-3,94	0	0	probably_damaging	0,99	neutral	0,33	neutral	4,56	neutral	-1,11	deleterious	-3,21	high_impact	3,53	neutral	0,64	neutral	0,45	deleterious	2,44	19,05	0,28	0,45	neutral	0,4	disease	0,75	disease	0,53	disease	0,63	3	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,78	low_impact	-2,59	medium_impact	0,06	high_impact	2,01	0,85	0,9	57,63	8,6	N	0,41	N	0,99	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14805	14805	A	C	MI.8445	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	59	20	D	A	gAc/gCc	8,9	1	0	probably_damaging	0,99	neutral	0,51	neutral	4,59	neutral	-0,7	deleterious	-5,14	high_impact	3,84	neutral	0,82	neutral	0,47	deleterious	2,37	18,63	0,04	0,35	neutral	0,37	disease	0,75	disease	0,6	disease	0,67	3	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,78	low_impact	-2,59	medium_impact	0,23	high_impact	2,29	0,39	0,8	57,63	8,6	P	0,56	P	0,95	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14805	14805	A	T	MI.8446	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	59	20	D	V	gAc/gTc	8,9	1	0	probably_damaging	1	neutral	0,52	neutral	4,52	neutral	-1,93	deleterious	-5,8	high_impact	4,14	neutral	0,81	neutral	0,48	deleterious	4,02	23,6	0,02	0,35	disease	0,61	disease	0,89	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,24	high_impact	2,57	0,13	0,8	57,63	8,6	P	0,57	P	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14805	14805	A	G	MI.8447	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	59	20	D	G	gAc/gGc	8,9	1	0	probably_damaging	1	neutral	0,33	neutral	4,53	neutral	-1,47	deleterious	-4,5	high_impact	3,73	neutral	0,8	neutral	0,47	deleterious	4,05	23,7	0,04	0,35	disease	0,59	disease	0,82	disease	0,62	disease	0,68	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,06	high_impact	2,19	0,31	0,8	57,63	8,6	P	0,59	P	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14806	14806	C	G	MI.8448	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	60	20	D	E	gaC/gaG	6,84	1	0	probably_damaging	0,95	neutral	0,28	neutral	4,65	neutral	0,05	deleterious	-2,58	medium_impact	3,12	neutral	0,84	neutral	0,46	deleterious	1,9	15,59	0,16	0,45	neutral	0,37	disease	0,76	disease	0,51	disease	0,6	2	neutral	0,96	neutral	0,17	deleterious	1	deleterious	0,77	low_impact	-1,92	medium_impact	0	medium_impact	1,64	0,51	0,8	57,63	8,6	P	0,52	P	1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14806	14806	C	A	MI.8449	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	60	20	D	E	gaC/gaA	6,84	1	0	probably_damaging	0,95	neutral	0,28	neutral	4,65	neutral	0,05	deleterious	-2,58	medium_impact	3,12	neutral	0,84	neutral	0,46	deleterious	2,24	17,8	0,16	0,45	neutral	0,37	disease	0,76	disease	0,51	disease	0,6	2	neutral	0,96	neutral	0,17	deleterious	1	deleterious	0,77	low_impact	-1,92	medium_impact	0	medium_impact	1,64	0,51	0,8	57,63	8,6	P	0,54	P	1	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8923	8923	A	G	MI.845	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	397	133	T	A	Aca/Gca	-9,59	0	0	probably_damaging	0,99	neutral	0,28	neutral	4,28	neutral	-0,69	deleterious	-4,44	low_impact	1,6	neutral	0,93	neutral	0,62	deleterious	3,48	23,1	0,56	0,65	disease	0,61	neutral	0,36	disease	0,75	disease	0,62	2	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,69	low_impact	-2,65	medium_impact	0,06	medium_impact	0,27	0,49	0,9	50	8,72	N	0,39	N	0,63	polymorphism	0,51	0,09	rs200329150	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14807	14807	C	A	MI.8450	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	61	21	L	I	Ctc/Atc	-1,42	0	0	probably_damaging	0,98	neutral	0,4	neutral	4,53	neutral	-1,86	neutral	-1,3	high_impact	3,96	neutral	0,87	damaging	0,06	deleterious	2,47	19,27	0,15	0,45	neutral	0,37	disease	0,63	disease	0,53	disease	0,58	1	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,75	low_impact	-2,31	medium_impact	0,13	high_impact	2,4	0,56	0,8	57,89	8,86	N	0,28	N	0,83	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14807	14807	C	G	MI.8451	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	61	21	L	V	Ctc/Gtc	-1,42	0	0	probably_damaging	0,96	neutral	0,5	neutral	4,55	neutral	-1,64	neutral	-1,96	high_impact	4,64	neutral	0,81	damaging	0,08	neutral	1,47	13,17	0,14	0,4	neutral	0,33	disease	0,57	disease	0,55	disease	0,62	2	neutral	0,96	neutral	0,27	deleterious	2	deleterious	0,72	low_impact	-2,02	medium_impact	0,22	high_impact	3,02	0,49	0,8	57,89	8,86	N	0,43	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14807	14807	C	T	MI.8452	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	61	21	L	F	Ctc/Ttc	-1,42	0	0	probably_damaging	1	neutral	0,7	neutral	4,48	neutral	-2,37	deleterious	-2,61	high_impact	3,78	neutral	0,88	damaging	0,08	deleterious	3,5	23,1	0,06	0,35	neutral	0,36	disease	0,69	disease	0,64	disease	0,67	3	deleterious	0,99	neutral	0,35	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	0,42	high_impact	2,24	0,51	0,8	57,89	8,86	N	0,23	N	0,97	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14808	14808	T	G	MI.8453	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	62	21	L	R	cTc/cGc	-0,04	0	0	probably_damaging	1	neutral	0,35	neutral	4,45	neutral	-2,39	deleterious	-3,91	high_impact	5,2	neutral	0,83	damaging	0,03	deleterious	3,92	23,5	0,01	0,35	disease	0,58	disease	0,84	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,08	high_impact	3,53	0,13	0,8	57,89	8,86	P	0,66	P	0,99	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14808	14808	T	A	MI.8454	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	62	21	L	H	cTc/cAc	-0,04	0	0	probably_damaging	1	neutral	0,54	neutral	4,45	deleterious	-3,1	deleterious	-4,57	high_impact	4,22	neutral	0,88	damaging	0,06	deleterious	3,94	23,5	0,02	0,35	disease	0,68	disease	0,78	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,26	high_impact	2,64	0,21	0,8	57,89	8,86	N	0,3	N	0,95	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14808	14808	T	C	MI.8455	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	62	21	L	P	cTc/cCc	-0,04	0	0	probably_damaging	1	neutral	0,21	neutral	4,43	neutral	-2,99	deleterious	-4,57	high_impact	5,2	neutral	0,86	damaging	0,03	deleterious	3,72	23,3	0,01	0,35	disease	0,69	disease	0,76	disease	0,58	disease	0,67	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,09	high_impact	3,53	0,26	0,8	57,89	8,86	P	0,6	P	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14810	14810	C	G	MI.8456	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	64	22	P	A	Ccc/Gcc	-20	0	0	probably_damaging	0,99	neutral	0,51	neutral	4,44	neutral	-1,05	deleterious	-5,26	high_impact	4,42	neutral	0,94	damaging	0,15	deleterious	2,53	19,69	0,07	0,35	disease	0,56	disease	0,65	disease	0,64	disease	0,67	3	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,77	low_impact	-2,59	medium_impact	0,23	high_impact	2,82	0,73	0,85	57,63	8,82	N	0,38	N	0,82	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14810	14810	C	A	MI.8457	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	64	22	P	T	Ccc/Acc	-20	0	0	probably_damaging	1	neutral	0,39	neutral	4,42	neutral	-1,81	deleterious	-5,26	high_impact	5,32	neutral	0,92	damaging	0,11	deleterious	3,4	23	0,07	0,35	disease	0,62	disease	0,8	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,12	high_impact	3,64	0,54	0,8	57,63	8,82	P	0,62	P	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14810	14810	C	T	MI.8458	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	64	22	P	S	Ccc/Tcc	-20	0	0	probably_damaging	1	neutral	0,42	neutral	4,42	neutral	-2,03	deleterious	-5,26	high_impact	4,76	neutral	0,93	damaging	0,1	deleterious	3,6	23,2	0,08	0,35	disease	0,51	disease	0,79	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,15	high_impact	3,13	0,15	0,8	57,63	8,82	P	0,6	P	0,85	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14811	14811	C	A	MI.8459	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	65	22	P	H	cCc/cAc	7,07	1	0	probably_damaging	1	neutral	0,54	neutral	4,38	neutral	-2,95	deleterious	-5,93	high_impact	5,32	neutral	0,91	damaging	0,09	deleterious	3,86	23,5	0,04	0,35	disease	0,77	disease	0,84	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,26	high_impact	3,64	0,28	0,8	57,63	8,82	P	0,69	P	0,71	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8923	8923	A	T	MI.846	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	397	133	T	S	Aca/Tca	-9,59	0	0	probably_damaging	0,99	neutral	0,17	neutral	4,26	neutral	-1,77	deleterious	-3,52	medium_impact	2,43	neutral	0,92	neutral	0,61	deleterious	3,28	22,8	0,47	0,65	disease	0,51	neutral	0,42	disease	0,66	neutral	0,44	1	deleterious	0,99	neutral	0,09	deleterious	1	deleterious	0,7	low_impact	-2,65	medium_impact	-0,1	medium_impact	0,99	0,64	0,9	50	8,72	N	0,44	N	0,88	polymorphism	0,75	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14811	14811	C	T	MI.8460	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	65	22	P	L	cCc/cTc	7,07	1	0	probably_damaging	1	neutral	0,7	neutral	4,46	neutral	-0,56	deleterious	-6,58	high_impact	4,08	neutral	0,94	damaging	0,07	deleterious	4,21	23,9	0,05	0,35	disease	0,65	disease	0,85	disease	0,61	disease	0,71	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,42	high_impact	2,51	0,75	0,85	57,63	8,82	N	0,47	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14811	14811	C	G	MI.8461	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	65	22	P	R	cCc/cGc	7,07	1	0	probably_damaging	1	neutral	0,35	neutral	4,4	neutral	-2,01	deleterious	-5,93	high_impact	4,08	neutral	0,96	damaging	0,08	deleterious	3,4	23	0,03	0,35	disease	0,62	disease	0,86	disease	0,71	disease	0,76	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,08	high_impact	2,51	0,37	0,8	57,63	8,82	N	0,53	P	0,81	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14813	14813	A	C	MI.8462	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	67	23	T	P	Acc/Ccc	-10,14	0	0	possibly_damaging	0,48	neutral	0,4	neutral	4,55	neutral	-2,19	deleterious	-2,8	high_impact	4	neutral	0,93	neutral	0,38	deleterious	3,5	23,1	0,05	0,35	disease	0,58	disease	0,82	disease	0,54	disease	0,72	4	neutral	0,57	neutral	0,46	deleterious	1	deleterious	0,47	medium_impact	-0,7	medium_impact	0,13	high_impact	2,44	0,28	0,8	14,74	11,33	N	0,35	N	0,54	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14813	14813	A	T	MI.8463	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	67	23	T	S	Acc/Tcc	-10,14	0	0	benign	0,15	neutral	0,47	neutral	4,61	neutral	-0,66	neutral	-1,35	low_impact	1,71	neutral	0,96	neutral	0,77	deleterious	0,82	9,6	0,21	0,45	neutral	0,3	neutral	0,39	neutral	0,22	neutral	0,44	1	neutral	0,44	deleterious	0,66	neutral	-6	neutral	0,19	medium_impact	-0,03	medium_impact	0,19	medium_impact	0,36	0,54	0,8	14,74	11,33	N	0,42	N	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14813	14813	A	G	MI.8464	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	67	23	T	A	Acc/Gcc	-10,14	0	0	benign	0	neutral	0,58	neutral	4,71	neutral	-0,24	neutral	-1,31	neutral_impact	0,2	neutral	0,96	neutral	0,98	neutral	-0,26	0,82	0,18	0,45	neutral	0,18	neutral	0,09	neutral	0,2	neutral	0,28	4	neutral	0,41	deleterious	0,79	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,3	low_impact	-1,01	0,27	0,8	14,74	11,33	N	0,46	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14814	14814	C	T	MI.8465	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	68	23	T	I	aCc/aTc	-1,42	0	0	benign	0,32	neutral	0,46	neutral	4,66	neutral	-0,62	deleterious	-2,82	medium_impact	3,35	neutral	0,93	neutral	0,54	deleterious	3,47	23	0,08	0,35	disease	0,52	disease	0,79	neutral	0,34	disease	0,64	3	neutral	0,45	deleterious	0,57	neutral	-3	neutral	0,36	medium_impact	-0,43	medium_impact	0,18	medium_impact	1,85	0,39	0,8	14,74	11,33	N	0,31	N	0,37	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14814	14814	C	G	MI.8466	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	68	23	T	S	aCc/aGc	-1,42	0	0	benign	0,15	neutral	0,47	neutral	4,61	neutral	-0,66	neutral	-1,35	low_impact	1,71	neutral	0,96	neutral	0,77	deleterious	0,49	7,37	0,21	0,45	neutral	0,3	neutral	0,39	neutral	0,22	neutral	0,44	1	neutral	0,44	deleterious	0,66	neutral	-6	neutral	0,19	medium_impact	-0,03	medium_impact	0,19	medium_impact	0,36	0,54	0,8	14,74	11,33	N	0,42	N	0,38	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14814	14814	C	A	MI.8467	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	68	23	T	N	aCc/aAc	-1,42	0	0	possibly_damaging	0,48	neutral	0,37	neutral	4,57	neutral	-2,25	neutral	-2,49	high_impact	4,2	neutral	0,87	neutral	0,58	deleterious	1,91	15,66	0,21	0,45	neutral	0,4	disease	0,74	disease	0,6	disease	0,69	4	neutral	0,6	neutral	0,45	deleterious	1	neutral	0,4	medium_impact	-0,7	medium_impact	0,1	high_impact	2,62	0,48	0,8	14,74	11,33	N	0,42	N	0,6	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14816	14816	C	A	MI.8468	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	70	24	P	T	Cca/Aca	-7,38	0	0	probably_damaging	1	neutral	0,45	neutral	4,21	deleterious	-4,14	deleterious	-5,29	high_impact	5,02	neutral	0,82	damaging	0,08	deleterious	3,44	23	0,07	0,35	disease	0,94	disease	0,82	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,18	high_impact	3,36	0,52	0,8	59,21	8,75	P	0,66	P	0,96	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14816	14816	C	T	MI.8469	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	70	24	P	S	Cca/Tca	-7,38	0	0	probably_damaging	1	neutral	0,48	neutral	4,23	deleterious	-3,25	deleterious	-5,28	high_impact	4,04	neutral	0,84	damaging	0,07	deleterious	3,63	23,2	0,09	0,35	disease	0,92	disease	0,79	disease	0,67	disease	0,8	6	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,2	high_impact	2,48	0,17	0,8	59,21	8,75	N	0,28	N	0,9	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8923	8923	A	C	MI.847	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	397	133	T	P	Aca/Cca	-9,59	0	0	probably_damaging	1	deleterious	0	neutral	4,19	neutral	-1,89	deleterious	-5,4	medium_impact	3,32	neutral	0,77	neutral	0,49	deleterious	3,55	23,1	0,22	0,65	disease	0,87	disease	0,71	disease	0,76	disease	0,77	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,79	low_impact	-3,6	low_impact	-1,4	medium_impact	1,75	0,48	0,9	50	8,72	N	0,33	N	0,99	disease_causing	0,83	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14816	14816	C	G	MI.8470	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	70	24	P	A	Cca/Gca	-7,38	0	0	probably_damaging	0,99	neutral	0,57	neutral	4,24	deleterious	-3,87	deleterious	-5,29	high_impact	4,26	neutral	0,87	damaging	0,11	deleterious	2,51	19,56	0,08	0,35	disease	0,91	disease	0,66	disease	0,73	disease	0,75	5	deleterious	0,99	neutral	0,29	deleterious	2	deleterious	0,84	low_impact	-2,59	medium_impact	0,29	high_impact	2,67	0,61	0,8	59,21	8,75	N	0,32	N	0,84	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14817	14817	C	G	MI.8471	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	71	24	P	R	cCa/cGa	4,31	0,99	0	probably_damaging	1	neutral	0,34	neutral	4,2	deleterious	-4,34	deleterious	-5,97	high_impact	5,37	neutral	0,82	damaging	0,05	deleterious	3,43	23	0,04	0,35	disease	0,96	disease	0,86	disease	0,77	disease	0,86	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,07	high_impact	3,68	0,33	0,8	59,21	8,75	P	0,71	P	0,8	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14817	14817	C	A	MI.8472	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	71	24	P	Q	cCa/cAa	4,31	0,99	0	probably_damaging	1	neutral	0,28	neutral	4,2	deleterious	-4,9	deleterious	-5,3	high_impact	5,37	neutral	0,85	damaging	0,05	deleterious	3,92	23,5	0,06	0,35	disease	0,97	disease	0,85	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0	high_impact	3,68	0,37	0,8	59,21	8,75	P	0,71	P	0,86	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14817	14817	C	T	MI.8473	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	71	24	P	L	cCa/cTa	4,31	0,99	0	probably_damaging	1	neutral	0,7	neutral	4,21	deleterious	-4,62	deleterious	-6,64	high_impact	5,02	neutral	0,85	damaging	0,05	deleterious	4,24	23,9	0,05	0,35	disease	0,96	disease	0,83	disease	0,72	disease	0,81	6	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,42	high_impact	3,36	0,74	0,85	59,21	8,75	P	0,64	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14819	14819	T	C	MI.8474	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	73	25	S	P	Tcc/Ccc	-5,32	0	0	benign	0,01	neutral	0,37	neutral	4,55	neutral	-2,1	neutral	-2,13	low_impact	1,86	neutral	0,91	neutral	0,74	deleterious	2,34	18,43	0,05	0,35	disease	0,72	disease	0,76	neutral	0,31	disease	0,55	1	neutral	0,62	deleterious	0,68	neutral	-6	neutral	0,27	medium_impact	1,13	medium_impact	0,1	medium_impact	0,5	0,18	0,8	35	7,83	N	0,31	N	0,3	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14819	14819	T	A	MI.8475	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	73	25	S	T	Tcc/Acc	-5,32	0	0	benign	0,14	neutral	0,43	neutral	4,59	neutral	-1,1	neutral	-1,17	medium_impact	2,24	neutral	0,9	neutral	0,48	neutral	1,77	14,83	0,18	0,45	neutral	0,49	disease	0,65	neutral	0,29	neutral	0,46	1	neutral	0,49	deleterious	0,65	neutral	-3	neutral	0,23	medium_impact	0	medium_impact	0,16	medium_impact	0,84	0,49	0,8	35	7,83	N	0,34	N	0,65	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14819	14819	T	G	MI.8476	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	73	25	S	A	Tcc/Gcc	-5,32	0	0	benign	0,13	neutral	0,51	neutral	4,65	neutral	-0,21	neutral	-1,32	medium_impact	2,22	neutral	0,9	neutral	0,53	deleterious	0,72	8,99	0,25	0,45	neutral	0,37	neutral	0,48	neutral	0,3	neutral	0,43	1	neutral	0,4	deleterious	0,69	neutral	-3	neutral	0,21	medium_impact	0,04	medium_impact	0,23	medium_impact	0,82	0,36	0,8	35	7,83	N	0,35	N	0,39	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14820	14820	C	G	MI.8477	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	74	25	S	C	tCc/tGc	0,41	0,02	0	probably_damaging	0,98	neutral	0,18	neutral	4,52	deleterious	-4,36	deleterious	-2,6	high_impact	3,52	neutral	0,84	neutral	0,34	deleterious	3,35	22,9	0,06	0,35	disease	0,77	disease	0,83	neutral	0,46	disease	0,71	4	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,78	low_impact	-2,31	medium_impact	-0,14	high_impact	2	0,23	0,8	35	7,83	N	0,36	N	0,53	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14820	14820	C	A	MI.8478	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	74	25	S	Y	tCc/tAc	0,41	0,02	0	probably_damaging	0,94	neutral	1	neutral	4,54	neutral	-2,15	deleterious	-3,23	high_impact	3,96	neutral	0,84	neutral	0,39	deleterious	3,98	23,6	0,05	0,35	disease	0,67	disease	0,87	disease	0,58	disease	0,71	4	neutral	0,94	deleterious	0,53	deleterious	2	deleterious	0,78	low_impact	-1,85	high_impact	1,85	high_impact	2,4	0,2	0,8	35	7,83	N	0,25	N	0,99	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14820	14820	C	T	MI.8479	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	74	25	S	F	tCc/tTc	0,41	0,02	0	probably_damaging	0,99	neutral	0,74	neutral	4,53	deleterious	-3,35	deleterious	-3,25	high_impact	4,07	neutral	0,78	neutral	0,43	deleterious	4,02	23,6	0,04	0,35	disease	0,61	disease	0,88	disease	0,58	disease	0,71	4	deleterious	0,99	neutral	0,38	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	0,47	high_impact	2,5	0,09	0,8	35	7,83	N	0,26	N	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8924	8924	C	A	MI.848	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	398	133	T	K	aCa/aAa	8,69	1	0	probably_damaging	1	neutral	0,06	neutral	4,23	neutral	-2,71	deleterious	-5,37	high_impact	4,36	neutral	0,82	neutral	0,46	deleterious	4,42	24,2	0,25	0,65	disease	0,71	disease	0,77	disease	0,81	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	-0,38	high_impact	2,64	0,68	0,9	50	8,72	P	0,64	P	1	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14822	14822	A	C	MI.8480	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	76	26	N	H	Aac/Cac	-10,37	0	0	probably_damaging	1	neutral	0,54	neutral	4,34	neutral	-2,64	deleterious	-3,23	high_impact	4,93	neutral	0,85	damaging	0,15	deleterious	2,81	21,4	0,25	0,45	disease	0,85	disease	0,74	disease	0,77	disease	0,81	6	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,26	high_impact	3,28	0,15	0,8	54,74	10,28	P	0,7	P	0,75	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14822	14822	A	T	MI.8481	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	76	26	N	Y	Aac/Tac	-10,37	0	0	probably_damaging	1	neutral	1	neutral	4,32	deleterious	-3,34	deleterious	-5,15	high_impact	5,28	neutral	0,86	damaging	0,15	deleterious	3,53	23,1	0,06	0,35	disease	0,89	disease	0,82	disease	0,78	disease	0,83	7	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,85	low_impact	-3,53	high_impact	1,85	high_impact	3,6	0,15	0,8	54,74	10,28	P	0,65	P	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14822	14822	A	G	MI.8482	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	76	26	N	D	Aac/Gac	-10,37	0	0	probably_damaging	0,98	neutral	0,21	neutral	4,36	neutral	-2,33	deleterious	-3,17	high_impact	4,58	neutral	0,84	damaging	0,13	deleterious	2,02	16,34	0,37	0,5	disease	0,61	disease	0,65	disease	0,77	disease	0,75	5	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,77	low_impact	-2,31	medium_impact	-0,09	high_impact	2,97	0,25	0,8	54,74	10,28	N	0,53	P	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14823	14823	A	T	MI.8483	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	77	26	N	I	aAc/aTc	5,46	0,99	0	probably_damaging	1	neutral	0,41	neutral	4,31	deleterious	-3,79	deleterious	-5,77	high_impact	4,58	neutral	0,86	damaging	0,15	deleterious	3,83	23,4	0,08	0,35	disease	0,86	disease	0,88	disease	0,74	disease	0,82	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,14	high_impact	2,97	0,11	0,8	54,74	10,28	P	0,64	P	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14823	14823	A	C	MI.8484	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	77	26	N	T	aAc/aCc	5,46	0,99	0	probably_damaging	0,99	neutral	0,39	neutral	4,36	neutral	-2,47	deleterious	-3,73	high_impact	4,08	neutral	0,86	damaging	0,18	neutral	1,71	14,44	0,2	0,45	disease	0,66	disease	0,75	disease	0,7	disease	0,7	4	deleterious	0,99	neutral	0,2	deleterious	2	deleterious	0,81	low_impact	-2,59	medium_impact	0,12	high_impact	2,51	0,22	0,8	54,74	10,28	P	0,56	P	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14823	14823	A	G	MI.8485	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	77	26	N	S	aAc/aGc	5,46	0,99	0	probably_damaging	0,96	neutral	0,43	neutral	4,4	neutral	-1,82	deleterious	-2,93	medium_impact	2,17	neutral	0,95	neutral	0,82	deleterious	0,06	3,21	0,33	0,5	neutral	0,32	disease	0,59	disease	0,58	neutral	0,44	1	neutral	0,95	neutral	0,24	deleterious	1	deleterious	0,73	low_impact	-2,02	medium_impact	0,16	medium_impact	0,78	0,2	0,8	54,74	10,28	P	0,53	P	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14824	14824	C	A	MI.8486	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	78	26	N	K	aaC/aaA	3,17	0,98	0	probably_damaging	1	neutral	0,29	neutral	4,41	neutral	-1,78	deleterious	-3,79	high_impact	4,47	neutral	0,86	damaging	0,13	deleterious	4,07	23,7	0,24	0,45	disease	0,69	disease	0,74	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,01	high_impact	2,87	0,3	0,8	54,74	10,28	P	0,56	P	0,93	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14824	14824	C	G	MI.8487	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	78	26	N	K	aaC/aaG	3,17	0,98	0	probably_damaging	1	neutral	0,29	neutral	4,41	neutral	-1,78	deleterious	-3,79	high_impact	4,47	neutral	0,86	damaging	0,13	deleterious	3,54	23,1	0,24	0,45	disease	0,69	disease	0,74	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,01	high_impact	2,87	0,3	0,8	54,74	10,28	P	0,56	P	0,93	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14825	14825	A	T	MI.8488	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	79	27	I	F	Atc/Ttc	-0,96	0,02	0	probably_damaging	0,99	neutral	0,72	neutral	4,51	neutral	-0,99	deleterious	-2,53	medium_impact	2,89	neutral	0,92	neutral	0,43	deleterious	1,86	15,36	0,05	0,35	disease	0,72	disease	0,79	disease	0,65	disease	0,69	4	deleterious	0,99	neutral	0,37	deleterious	1	deleterious	0,8	low_impact	-2,59	medium_impact	0,44	medium_impact	1,43	0,68	0,85	22,89	12,38	N	0,23	N	0,96	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14825	14825	A	C	MI.8489	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	79	27	I	L	Atc/Ctc	-0,96	0,02	0	probably_damaging	0,95	neutral	0,68	neutral	4,71	neutral	0,14	neutral	-0,97	low_impact	1,38	neutral	0,92	neutral	0,76	deleterious	0,53	7,67	0,23	0,45	neutral	0,27	disease	0,5	neutral	0,37	neutral	0,44	1	neutral	0,94	neutral	0,37	neutral	-2	deleterious	0,59	low_impact	-1,92	medium_impact	0,4	medium_impact	0,06	0,69	0,85	22,89	12,38	N	0,26	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8924	8924	C	T	MI.849	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	398	133	T	M	aCa/aTa	8,69	1	0	probably_damaging	1	deleterious	0	neutral	4,25	neutral	-1,91	deleterious	-5,38	high_impact	4,36	neutral	0,88	neutral	0,62	deleterious	4,04	23,7	0,43	0,65	disease	0,8	disease	0,66	disease	0,81	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,74	low_impact	-3,6	low_impact	-1,4	high_impact	2,64	0,64	0,9	50	8,72	P	0,6	P	0,98	disease_causing	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14825	14825	A	G	MI.8490	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	79	27	I	V	Atc/Gtc	-0,96	0,02	0	possibly_damaging	0,87	neutral	0,51	neutral	4,55	neutral	-0,75	neutral	-0,68	high_impact	4,53	neutral	0,91	neutral	0,5	neutral	0,91	10,14	0,5	0,6	neutral	0,38	neutral	0,41	disease	0,66	neutral	0,44	1	neutral	0,86	neutral	0,32	deleterious	1	deleterious	0,57	low_impact	-1,5	medium_impact	0,23	high_impact	2,92	0,58	0,8	22,89	12,38	N	0,48	N	0,52	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14826	14826	T	A	MI.8491	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	80	27	I	N	aTc/aAc	5,46	1	0	probably_damaging	1	neutral	0,4	neutral	4,41	deleterious	-3,37	deleterious	-4,58	high_impact	4,39	neutral	0,83	neutral	0,41	deleterious	4,05	23,7	0,04	0,35	disease	0,93	disease	0,85	disease	0,75	disease	0,85	7	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,13	high_impact	2,79	0,34	0,8	22,89	12,38	P	0,65	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14826	14826	T	G	MI.8492	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	80	27	I	S	aTc/aGc	5,46	1	0	probably_damaging	1	neutral	0,48	neutral	4,46	neutral	-1,71	deleterious	-3,9	high_impact	4,38	neutral	0,84	neutral	0,39	deleterious	3,85	23,4	0,02	0,35	disease	0,87	disease	0,83	disease	0,72	disease	0,79	6	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,2	high_impact	2,78	0,22	0,8	22,89	12,38	P	0,63	P	0,96	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14826	14826	T	C	MI.8493	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	80	27	I	T	aTc/aCc	5,46	1	0	probably_damaging	1	neutral	0,4	neutral	4,46	neutral	-1,8	deleterious	-3,22	high_impact	5,08	neutral	0,77	neutral	0,39	deleterious	2,84	21,6	0,03	0,35	disease	0,78	disease	0,75	disease	0,74	disease	0,76	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,13	high_impact	3,42	0,25	0,8	22,89	12,38	P	0,76	P	0,98	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14827	14827	C	G	MI.8494	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	81	27	I	M	atC/atG	3,63	1	0	probably_damaging	1	neutral	0,23	neutral	4,45	neutral	-2,35	neutral	-1,74	high_impact	3,63	neutral	0,75	neutral	0,32	deleterious	2,85	21,6	0,08	0,35	disease	0,68	disease	0,59	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,75	low_impact	-3,53	medium_impact	-0,06	high_impact	2,1	0,71	0,85	22,89	12,38	N	0,49	N	0,79	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14827	14827	C	A	MI.8495	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	81	27	I	M	atC/atA	3,63	1	0	probably_damaging	1	neutral	0,23	neutral	4,45	neutral	-2,35	neutral	-1,74	high_impact	3,63	neutral	0,75	neutral	0,32	deleterious	3,27	22,8	0,08	0,35	disease	0,68	disease	0,59	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,75	low_impact	-3,53	medium_impact	-0,06	high_impact	2,1	0,71	0,85	22,89	12,38	N	0,49	N	0,79	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14828	14828	T	A	MI.8496	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	82	28	S	T	Tcc/Acc	-4,4	0	0	probably_damaging	0,93	neutral	0,39	neutral	4,52	neutral	-2,05	neutral	-2,01	medium_impact	2,85	neutral	0,98	neutral	0,45	neutral	1,71	14,46	0,14	0,4	disease	0,6	disease	0,68	disease	0,63	disease	0,6	2	neutral	0,93	neutral	0,23	deleterious	1	deleterious	0,75	low_impact	-1,78	medium_impact	0,12	medium_impact	1,39	0,56	0,8	57,89	9,06	N	0,33	N	0,7	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14828	14828	T	C	MI.8497	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	82	28	S	P	Tcc/Ccc	-4,4	0	0	probably_damaging	0,99	neutral	0,21	neutral	4,46	neutral	-2,86	deleterious	-3,4	high_impact	4,51	neutral	0,97	damaging	0,06	deleterious	2,15	17,18	0,04	0,35	disease	0,7	disease	0,83	disease	0,7	disease	0,75	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-2,59	medium_impact	-0,09	high_impact	2,9	0,32	0,8	57,89	9,06	N	0,46	N	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14828	14828	T	G	MI.8498	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	82	28	S	A	Tcc/Gcc	-4,4	0	0	probably_damaging	0,96	neutral	0,5	neutral	4,53	neutral	-2,33	neutral	-2,05	high_impact	5,2	neutral	0,96	damaging	0,13	neutral	1,69	14,35	0,16	0,45	neutral	0,5	disease	0,64	disease	0,7	disease	0,71	4	neutral	0,96	neutral	0,27	deleterious	2	deleterious	0,7	low_impact	-2,02	medium_impact	0,22	high_impact	3,53	0,43	0,8	57,89	9,06	P	0,65	P	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14829	14829	C	T	MI.8499	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	83	28	S	F	tCc/tTc	7,3	1	0	probably_damaging	1	neutral	0,7	neutral	4,45	deleterious	-3,93	deleterious	-4,08	high_impact	4,86	neutral	0,95	damaging	0,08	deleterious	3,93	23,5	0,04	0,35	disease	0,88	disease	0,88	disease	0,68	disease	0,79	6	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,42	high_impact	3,22	0,12	0,8	57,89	9,06	P	0,74	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8564	8564	C	A	MI.85	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	38	13	T	K	aCa/aAa	0,13	0	0	probably_damaging	1	neutral	0,06	neutral	4,58	neutral	-0,78	deleterious	-3,5	low_impact	1,29	neutral	0,8	neutral	0,6	deleterious	4,16	23,8	0,28	0,65	disease	0,64	disease	0,87	disease	0,66	disease	0,6	2	deleterious	1	neutral	0,03	neutral	-2	deleterious	0,77	low_impact	-3,6	medium_impact	-0,38	medium_impact	0,01	0,65	0,9	15,49	16,77	N	0,27	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8926	8926	C	T	MI.850	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	400	134	P	S	Cct/Tct	-9,59	0	0	probably_damaging	1	deleterious	0,04	neutral	3,52	deleterious	-3,11	deleterious	-7,16	medium_impact	3,19	neutral	0,67	damaging	0,13	deleterious	3,95	23,6	0,45	0,65	disease	0,74	disease	0,73	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,8	low_impact	-3,6	medium_impact	-0,49	medium_impact	1,64	0,34	0,9	49,56	8,76	N	0,27	N	0,82	disease_causing	0,94	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14829	14829	C	A	MI.8500	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	83	28	S	Y	tCc/tAc	7,3	1	0	probably_damaging	1	neutral	1	neutral	4,46	deleterious	-3,89	deleterious	-4,08	high_impact	4,51	neutral	0,95	damaging	0,08	deleterious	3,81	23,4	0,03	0,35	disease	0,87	disease	0,86	disease	0,68	disease	0,79	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,85	low_impact	-3,53	high_impact	1,85	high_impact	2,9	0,31	0,8	57,89	9,06	N	0,52	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14829	14829	C	G	MI.8501	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	83	28	S	C	tCc/tGc	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	4,44	deleterious	-5,45	deleterious	-3,41	high_impact	5,2	neutral	0,95	damaging	0,07	deleterious	3,25	22,8	0,04	0,35	disease	0,86	disease	0,81	disease	0,7	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,14	high_impact	3,53	0,26	0,8	57,89	9,06	P	0,74	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14831	14831	G	T	MI.8502	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	85	29	A	S	Gca/Tca	-7,61	0	0,01	benign	0,03	neutral	0,47	neutral	4,67	neutral	-0,47	neutral	-0,77	neutral_impact	0,59	neutral	0,98	neutral	0,95	neutral	-0,79	0,04	0,15	0,45	neutral	0,18	neutral	0,25	neutral	0,24	neutral	0,43	1	neutral	0,5	deleterious	0,72	neutral	-6	neutral	0,11	medium_impact	0,68	medium_impact	0,19	medium_impact	-0,66	0,42	0,8	24,47	35,88	N	0,51	P	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14831	14831	G	A	MI.8503	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	85	29	A	T	Gca/Aca	-7,61	0	0,01	benign	0	neutral	0,39	neutral	4,65	neutral	-0,51	neutral	-0,89	low_impact	1,27	neutral	0,99	neutral	0,91	neutral	1,05	10,95	0,12	0,4	neutral	0,34	neutral	0,49	neutral	0,27	neutral	0,46	1	neutral	0,61	deleterious	0,7	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,12	medium_impact	-0,04	0,65	0,8	24,47	35,88	N	0,46	N	0,04	disease_causing_automatic	0	0,02	rs199795644	Pathogenic	Leber's_optic_atrophy	RCV000055706.1	MedGen:OMIM:SNOMED_CT	.	.	CPD	7,43	G14831A	LHON	+	-	Reported	1
chrM	14831	14831	G	C	MI.8504	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	85	29	A	P	Gca/Cca	-7,61	0	0,01	benign	0,08	neutral	0,21	neutral	4,6	neutral	-2,47	neutral	-2,11	high_impact	3,65	neutral	0,98	neutral	0,36	deleterious	3,39	23	0,04	0,35	disease	0,6	disease	0,85	disease	0,59	disease	0,74	5	neutral	0,77	deleterious	0,57	neutral	-2	neutral	0,29	medium_impact	0,26	medium_impact	-0,09	high_impact	2,12	0,43	0,8	24,47	35,88	N	0,39	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14832	14832	C	T	MI.8505	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	86	29	A	V	gCa/gTa	-1,65	0	0	benign	0,01	neutral	0,51	neutral	4,71	neutral	0,11	neutral	-0,9	low_impact	1,84	neutral	0,95	neutral	0,65	neutral	1,36	12,56	0,09	0,35	neutral	0,29	neutral	0,39	neutral	0,35	neutral	0,44	1	neutral	0,48	deleterious	0,75	neutral	-6	neutral	0,11	medium_impact	1,13	medium_impact	0,23	medium_impact	0,48	0,62	0,8	24,47	35,88	N	0,35	N	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14832	14832	C	A	MI.8506	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	86	29	A	E	gCa/gAa	-1,65	0	0	benign	0,09	neutral	0,27	neutral	4,62	neutral	-0,73	neutral	-1,97	high_impact	4,34	neutral	0,93	neutral	0,48	deleterious	4,04	23,7	0,03	0,35	neutral	0,43	disease	0,8	disease	0,6	disease	0,73	5	neutral	0,7	deleterious	0,59	neutral	-2	neutral	0,23	medium_impact	0,21	medium_impact	-0,01	high_impact	2,75	0,3	0,8	24,47	35,88	N	0,42	N	0,63	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14832	14832	C	G	MI.8507	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	86	29	A	G	gCa/gGa	-1,65	0	0	benign	0,01	neutral	0,35	neutral	4,6	neutral	-1,54	neutral	-1,93	medium_impact	3,1	neutral	0,97	neutral	0,81	deleterious	0,85	9,8	0,12	0,4	disease	0,51	neutral	0,48	neutral	0,41	neutral	0,43	1	neutral	0,64	deleterious	0,67	neutral	-3	neutral	0,14	medium_impact	1,13	medium_impact	0,08	medium_impact	1,62	0,57	0,8	24,47	35,88	N	0,39	N	0,32	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14834	14834	T	G	MI.8508	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	88	30	W	G	Tga/Gga	-7,16	0	0	probably_damaging	0,99	neutral	0,39	neutral	4,46	deleterious	-3,02	deleterious	-7,39	high_impact	4,5	neutral	0,75	damaging	0,13	deleterious	2,13	17,08	0,04	0,35	disease	0,72	disease	0,83	disease	0,76	disease	0,78	6	deleterious	0,99	neutral	0,2	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	0,12	high_impact	2,89	0,15	0,8	54,74	8,72	N	0,43	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14834	14834	T	C	MI.8509	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	88	30	W	R	Tga/Cga	-7,16	0	0	probably_damaging	1	neutral	0,34	neutral	4,47	neutral	-2,92	deleterious	-7,79	high_impact	4,15	neutral	0,65	damaging	0,06	deleterious	3,15	22,6	0,02	0,35	disease	0,69	disease	0,91	disease	0,81	disease	0,83	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,07	high_impact	2,57	0,15	0,8	54,74	8,72	N	0,42	N	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8926	8926	C	G	MI.851	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	400	134	P	A	Cct/Gct	-9,59	0	0	probably_damaging	1	deleterious	0	neutral	3,48	neutral	-2,97	deleterious	-7,16	high_impact	4,06	neutral	0,69	damaging	0,15	deleterious	3,1	22,5	0,3	0,65	disease	0,74	disease	0,56	disease	0,72	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,6	low_impact	-1,4	high_impact	2,38	0,76	0,9	49,56	8,76	N	0,31	N	0,79	disease_causing	0,9	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14835	14835	G	C	MI.8510	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	89	30	W	S	tGa/tCa	5,69	1	0	probably_damaging	1	neutral	0,51	neutral	4,49	neutral	-1,94	deleterious	-7,71	high_impact	3,64	neutral	0,74	damaging	0,1	deleterious	3,43	23	0,03	0,35	neutral	0,43	disease	0,91	disease	0,75	disease	0,79	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,23	high_impact	2,11	0,15	0,8	54,74	8,72	N	0,49	N	0,99	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14835	14835	G	T	MI.8511	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	89	30	W	L	tGa/tTa	5,69	1	0	probably_damaging	0,99	neutral	0,71	neutral	4,68	neutral	0,07	deleterious	-6,73	medium_impact	2,42	neutral	0,75	damaging	0,08	deleterious	2,39	18,73	0,06	0,35	neutral	0,2	disease	0,79	disease	0,62	disease	0,51	0	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,73	low_impact	-2,59	medium_impact	0,43	medium_impact	1	0,14	0,8	54,74	8,72	N	0,36	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14836	14836	A	T	MI.8512	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	90	30	W	C	tgA/tgT	5	1	0	probably_damaging	1	neutral	0,19	neutral	4,45	deleterious	-3,65	deleterious	-7,12	high_impact	5,2	neutral	0,77	damaging	0,05	deleterious	3,83	23,4	0,03	0,35	disease	0,76	disease	0,92	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,12	high_impact	3,53	0,21	0,8	54,74	8,72	P	0,65	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14836	14836	A	C	MI.8513	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	90	30	W	C	tgA/tgC	5	1	0	probably_damaging	1	neutral	0,19	neutral	4,45	deleterious	-3,65	deleterious	-7,12	high_impact	5,2	neutral	0,77	damaging	0,05	deleterious	3,85	23,4	0,03	0,35	disease	0,76	disease	0,92	disease	0,76	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,12	high_impact	3,53	0,21	0,8	54,74	8,72	P	0,64	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14837	14837	T	G	MI.8514	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	91	31	W	G	Tga/Gga	4,54	1	0	probably_damaging	1	neutral	0,42	neutral	3,9	deleterious	-5,72	deleterious	-9,03	high_impact	5,34	neutral	0,82	damaging	0,1	deleterious	3,51	23,1	0,02	0,35	disease	0,93	disease	0,85	disease	0,8	disease	0,86	7	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,15	high_impact	3,66	0,1	0,8	57,37	8,91	P	0,68	P	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14837	14837	T	C	MI.8515	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	91	31	W	R	Tga/Cga	4,54	1	0	probably_damaging	1	neutral	0,33	neutral	3,9	deleterious	-5,46	deleterious	-9,69	high_impact	5	neutral	0,77	damaging	0,06	deleterious	3,36	22,9	0,01	0,35	disease	0,96	disease	0,91	disease	0,83	disease	0,85	7	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,06	high_impact	3,35	0,16	0,8	57,37	8,91	P	0,63	P	0,99	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14838	14838	G	T	MI.8516	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	92	31	W	L	tGa/tTa	4,54	1	0	probably_damaging	1	neutral	0,9	neutral	3,94	deleterious	-3,5	deleterious	-9,03	high_impact	4,3	neutral	0,85	damaging	0,07	deleterious	3,86	23,5	0,02	0,35	disease	0,92	disease	0,87	disease	0,79	disease	0,87	7	deleterious	1	neutral	0,45	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,74	high_impact	2,71	0,13	0,8	57,37	8,91	P	0,54	P	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14838	14838	G	C	MI.8517	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	92	31	W	S	tGa/tCa	4,54	1	0	probably_damaging	1	neutral	0,55	neutral	3,91	deleterious	-4,88	deleterious	-9,69	high_impact	4,3	neutral	0,85	damaging	0,09	deleterious	3,71	23,3	0,02	0,35	disease	0,96	disease	0,93	disease	0,79	disease	0,85	7	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,27	high_impact	2,71	0,1	0,8	57,37	8,91	N	0,53	P	0,99	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14839	14839	A	T	MI.8518	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	93	31	W	C	tgA/tgT	7,3	1	0	probably_damaging	1	neutral	0,19	neutral	3,89	deleterious	-6,57	deleterious	-9,03	high_impact	5,34	neutral	0,82	damaging	0,05	deleterious	3,91	23,5	0,02	0,35	disease	0,98	disease	0,93	disease	0,8	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,12	high_impact	3,66	0,17	0,8	57,37	8,91	P	0,64	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14839	14839	A	C	MI.8519	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	93	31	W	C	tgA/tgC	7,3	1	0	probably_damaging	1	neutral	0,19	neutral	3,89	deleterious	-6,57	deleterious	-9,03	high_impact	5,34	neutral	0,82	damaging	0,05	deleterious	3,78	23,4	0,02	0,35	disease	0,98	disease	0,93	disease	0,8	disease	0,85	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,12	high_impact	3,66	0,17	0,8	57,37	8,91	P	0,63	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8926	8926	C	A	MI.852	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	400	134	P	T	Cct/Act	-9,59	0	0	probably_damaging	1	deleterious	0,03	neutral	3,48	deleterious	-3,55	deleterious	-7,16	high_impact	4,61	neutral	0,69	damaging	0,11	deleterious	3,77	23,4	0,3	0,65	disease	0,78	disease	0,74	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,81	low_impact	-3,6	medium_impact	-0,56	high_impact	2,85	0,74	0,9	49,56	8,76	N	0,41	N	0,93	disease_causing	0,93	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14840	14840	A	T	MI.8520	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	94	32	N	Y	Aac/Tac	0,87	0,98	0	probably_damaging	1	neutral	1	neutral	4,53	neutral	-1,81	deleterious	-5,58	high_impact	3,77	neutral	0,94	neutral	0,34	deleterious	3,54	23,1	0,05	0,35	disease	0,94	disease	0,87	disease	0,73	disease	0,82	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,87	low_impact	-3,53	high_impact	1,85	high_impact	2,23	0,27	0,8	57,11	8,6	N	0,38	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14840	14840	A	C	MI.8521	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	94	32	N	H	Aac/Cac	0,87	0,98	0	probably_damaging	1	neutral	0,54	neutral	4,5	neutral	-2,91	deleterious	-3,49	high_impact	4,96	neutral	0,94	damaging	0,23	deleterious	2,95	22,1	0,13	0,4	disease	0,91	disease	0,79	disease	0,78	disease	0,84	7	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,26	high_impact	3,31	0,29	0,8	57,11	8,6	P	0,68	P	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14840	14840	A	G	MI.8522	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	94	32	N	D	Aac/Gac	0,87	0,98	0	probably_damaging	0,99	neutral	0,2	neutral	4,5	neutral	-2,56	deleterious	-3,48	high_impact	4,62	neutral	0,92	neutral	0,38	deleterious	3,34	22,9	0,26	0,45	disease	0,71	disease	0,73	disease	0,78	disease	0,76	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	-0,1	high_impact	3	0,42	0,8	57,11	8,6	P	0,66	P	0,96	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14841	14841	A	G	MI.8523	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	95	32	N	S	aAc/aGc	6,84	1	0	probably_damaging	0,98	neutral	0,46	neutral	4,55	neutral	-1,59	deleterious	-3,48	high_impact	4,03	neutral	0,93	neutral	0,45	neutral	1,05	10,97	0,23	0,45	disease	0,73	disease	0,77	disease	0,71	disease	0,73	5	neutral	0,98	neutral	0,24	deleterious	2	deleterious	0,84	low_impact	-2,31	medium_impact	0,18	high_impact	2,47	0,33	0,8	57,11	8,6	P	0,64	P	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	A14841G	LHON helper mut.	-	+	Reported	1
chrM	14841	14841	A	T	MI.8524	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	95	32	N	I	aAc/aTc	6,84	1	0	probably_damaging	1	neutral	0,41	neutral	4,58	neutral	-1,69	deleterious	-6,27	high_impact	4,21	neutral	0,95	neutral	0,44	deleterious	3,54	23,1	0,05	0,35	disease	0,93	disease	0,9	disease	0,72	disease	0,82	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,14	high_impact	2,63	0,14	0,8	57,11	8,6	P	0,65	P	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14841	14841	A	C	MI.8525	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	95	32	N	T	aAc/aCc	6,84	1	0	probably_damaging	1	neutral	0,4	neutral	4,59	neutral	-1,68	deleterious	-4,18	high_impact	3,81	neutral	0,95	neutral	0,42	deleterious	2,82	21,5	0,12	0,4	disease	0,79	disease	0,8	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,13	high_impact	2,27	0,36	0,8	57,11	8,6	P	0,63	P	0,94	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14842	14842	C	A	MI.8526	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	96	32	N	K	aaC/aaA	8,44	1	0	probably_damaging	1	neutral	0,29	neutral	4,52	neutral	-2,1	deleterious	-4,18	high_impact	4,5	neutral	0,95	neutral	0,29	deleterious	4,14	23,8	0,13	0,4	disease	0,81	disease	0,82	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,01	high_impact	2,89	0,46	0,8	57,11	8,6	P	0,68	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14842	14842	C	G	MI.8527	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	96	32	N	K	aaC/aaG	8,44	1	0	probably_damaging	1	neutral	0,29	neutral	4,52	neutral	-2,1	deleterious	-4,18	high_impact	4,5	neutral	0,95	neutral	0,29	deleterious	3,72	23,3	0,13	0,4	disease	0,81	disease	0,82	disease	0,78	disease	0,8	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,01	high_impact	2,89	0,46	0,8	57,11	8,6	P	0,68	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14843	14843	T	A	MI.8528	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	97	33	F	I	Ttc/Atc	-1,42	0,01	0	benign	0,08	neutral	0,4	neutral	4,41	neutral	-1,88	deleterious	-4,22	high_impact	4,33	neutral	0,94	damaging	0,11	deleterious	2,8	21,4	0,1	0,4	disease	0,58	disease	0,86	disease	0,66	disease	0,73	5	neutral	0,55	deleterious	0,66	neutral	-2	deleterious	0,46	medium_impact	0,26	medium_impact	0,13	high_impact	2,74	0,55	0,8	53,68	7,81	N	0,36	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14843	14843	T	G	MI.8529	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	97	33	F	V	Ttc/Gtc	-1,42	0,01	0	benign	0,24	neutral	0,5	neutral	4,44	neutral	-1,57	deleterious	-4,94	high_impact	4,57	neutral	0,95	damaging	0,11	deleterious	3,66	23,2	0,07	0,35	disease	0,54	disease	0,85	disease	0,71	disease	0,76	5	neutral	0,4	deleterious	0,63	neutral	-2	deleterious	0,43	medium_impact	-0,26	medium_impact	0,22	high_impact	2,96	0,39	0,8	53,68	7,81	N	0,4	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8927	8927	C	G	MI.853	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	401	134	P	R	cCt/cGt	3,6	0,99	0	probably_damaging	1	deleterious	0	neutral	3,47	deleterious	-3,61	deleterious	-8,09	high_impact	4,61	neutral	0,61	damaging	0,1	deleterious	3,59	23,2	0,25	0,65	disease	0,78	disease	0,86	disease	0,78	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,6	low_impact	-1,4	high_impact	2,85	0,7	0,9	49,56	8,76	P	0,57	P	0,65	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14843	14843	T	C	MI.8530	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	97	33	F	L	Ttc/Ctc	-1,42	0,01	0	benign	0	neutral	0,65	neutral	4,55	neutral	0,02	deleterious	-4,19	medium_impact	2,93	neutral	0,97	neutral	0,3	deleterious	2,17	17,3	0,12	0,4	neutral	0,49	disease	0,79	disease	0,57	neutral	0,5	0	neutral	0,34	deleterious	0,83	neutral	-3	neutral	0,23	high_impact	2,07	medium_impact	0,37	medium_impact	1,47	0,69	0,85	53,68	7,81	N	0,23	N	0,92	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14844	14844	T	A	MI.8531	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	98	33	F	Y	tTc/tAc	7,3	1	0	benign	0,27	neutral	1	neutral	4,36	deleterious	-3	neutral	-2,09	medium_impact	3,42	neutral	0,95	damaging	0,11	deleterious	2,3	18,18	0,13	0,4	neutral	0,32	disease	0,79	disease	0,65	disease	0,52	0	neutral	0,27	deleterious	0,87	neutral	-3	deleterious	0,52	medium_impact	-0,33	high_impact	1,85	medium_impact	1,91	0,6	0,8	53,68	7,81	N	0,46	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14844	14844	T	C	MI.8532	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	98	33	F	S	tTc/tCc	7,3	1	0	possibly_damaging	0,7	neutral	0,4	neutral	4,36	neutral	-2,97	deleterious	-5,69	high_impact	4,57	neutral	0,93	damaging	0,08	deleterious	3,75	23,3	0,03	0,35	disease	0,69	disease	0,86	disease	0,68	disease	0,73	5	neutral	0,72	neutral	0,35	deleterious	1	deleterious	0,73	low_impact	-1,07	medium_impact	0,13	high_impact	2,96	0,26	0,8	53,68	7,81	P	0,6	P	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14844	14844	T	G	MI.8533	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	98	33	F	C	tTc/tGc	7,3	1	0	probably_damaging	0,92	neutral	0,18	neutral	4,33	deleterious	-4,32	deleterious	-5,68	high_impact	5,03	neutral	0,96	damaging	0,09	deleterious	3,9	23,5	0,04	0,35	disease	0,85	disease	0,89	disease	0,68	disease	0,77	5	neutral	0,95	neutral	0,13	deleterious	2	deleterious	0,79	low_impact	-1,72	medium_impact	-0,14	high_impact	3,37	0,23	0,8	53,68	7,81	P	0,69	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14845	14845	C	G	MI.8534	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	99	33	F	L	ttC/ttG	7,3	1	0	benign	0	neutral	0,65	neutral	4,55	neutral	0,02	deleterious	-4,19	medium_impact	2,93	neutral	0,97	neutral	0,3	deleterious	2,38	18,66	0,12	0,4	neutral	0,49	disease	0,79	disease	0,57	neutral	0,5	0	neutral	0,34	deleterious	0,83	neutral	-3	neutral	0,23	high_impact	2,07	medium_impact	0,37	medium_impact	1,47	0,69	0,85	53,68	7,81	N	0,5	N	0,92	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14845	14845	C	A	MI.8535	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	99	33	F	L	ttC/ttA	7,3	1	0	benign	0	neutral	0,65	neutral	4,55	neutral	0,02	deleterious	-4,19	medium_impact	2,93	neutral	0,97	neutral	0,3	deleterious	2,65	20,5	0,12	0,4	neutral	0,49	disease	0,79	disease	0,57	neutral	0,5	0	neutral	0,34	deleterious	0,83	neutral	-3	neutral	0,23	high_impact	2,07	medium_impact	0,37	medium_impact	1,47	0,69	0,85	53,68	7,81	N	0,5	N	0,92	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14846	14846	G	A	MI.8536	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	100	34	G	S	Ggc/Agc	-2,57	0	0	probably_damaging	1	neutral	0,4	neutral	2,9	deleterious	-7,32	deleterious	-4,44	high_impact	4,8	neutral	0,82	damaging	0,05	deleterious	3,96	23,6	0,05	0,35	disease	0,9	disease	0,89	disease	0,72	disease	0,81	6	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,13	high_impact	3,17	0,28	0,8	57,63	8,53	P	0,67	P	1	disease_causing_automatic	0	0,19	rs207459998	Pathogenic	Exercise_intolerance	RCV000010317.2	MedGen	skeletal muscle - myopathy	COSM1497294	.	.	G14846A	EXIT	-	+	Reported	5
chrM	14846	14846	G	T	MI.8537	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	100	34	G	C	Ggc/Tgc	-2,57	0	0	probably_damaging	1	neutral	0,18	neutral	2,85	deleterious	-10,73	deleterious	-6,67	high_impact	5,5	neutral	0,84	damaging	0,03	deleterious	3,99	23,6	0,03	0,35	disease	0,97	disease	0,95	disease	0,75	disease	0,81	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,14	high_impact	3,8	0,17	0,8	57,63	8,53	P	0,58	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14846	14846	G	C	MI.8538	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	100	34	G	R	Ggc/Cgc	-2,57	0	0	probably_damaging	1	neutral	0,35	neutral	2,84	deleterious	-9,22	deleterious	-5,93	high_impact	4,8	neutral	0,9	damaging	0,04	deleterious	3,75	23,3	0,03	0,35	disease	0,96	disease	0,93	disease	0,82	disease	0,84	7	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0,08	high_impact	3,17	0,31	0,8	57,63	8,53	P	0,67	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14847	14847	G	C	MI.8539	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	101	34	G	A	gGc/gCc	5,92	1	0	probably_damaging	1	neutral	0,51	neutral	2,91	deleterious	-7,32	deleterious	-4,44	high_impact	5,5	neutral	0,84	damaging	0,1	deleterious	2,83	21,5	0,05	0,35	disease	0,88	disease	0,84	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,23	high_impact	3,8	0,31	0,8	57,63	8,53	P	0,76	P	0,83	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8927	8927	C	A	MI.854	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	401	134	P	H	cCt/cAt	3,6	0,99	0	probably_damaging	1	deleterious	0	neutral	3,49	deleterious	-4,31	deleterious	-8,09	high_impact	3,71	neutral	0,65	damaging	0,08	deleterious	4,12	23,8	0,28	0,65	disease	0,8	disease	0,82	disease	0,75	disease	0,75	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,6	low_impact	-1,4	high_impact	2,08	0,73	0,9	49,56	8,76	N	0,42	N	0,64	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14847	14847	G	T	MI.8540	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	101	34	G	V	gGc/gTc	5,92	1	0	probably_damaging	1	neutral	0,5	neutral	2,85	deleterious	-9,84	deleterious	-6,67	high_impact	5,5	neutral	0,84	damaging	0,07	deleterious	3,6	23,2	0,03	0,35	disease	0,95	disease	0,92	disease	0,77	disease	0,83	7	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,22	high_impact	3,8	0,15	0,8	57,63	8,53	P	0,68	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14847	14847	G	A	MI.8541	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	101	34	G	D	gGc/gAc	5,92	1	0	probably_damaging	1	neutral	0,2	neutral	2,84	deleterious	-8,37	deleterious	-5,19	high_impact	4,61	neutral	0,79	damaging	0,05	deleterious	3,6	23,2	0,03	0,35	disease	0,94	disease	0,93	disease	0,82	disease	0,84	7	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,1	high_impact	2,99	0,17	0,8	57,63	8,53	P	0,6	P	1	polymorphism	1	0,19	.	.	.	.	.	.	COSM1138282	.	.	.	.	.	.	.	.
chrM	14849	14849	T	G	MI.8542	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	103	35	S	A	Tca/Gca	-11,74	0	0	probably_damaging	0,92	neutral	0,5	neutral	4,53	neutral	-0,63	neutral	-2,22	high_impact	4	neutral	0,88	damaging	0,14	neutral	1,67	14,25	0,17	0,45	disease	0,55	disease	0,78	disease	0,59	disease	0,67	3	neutral	0,91	neutral	0,29	deleterious	2	deleterious	0,67	low_impact	-1,72	medium_impact	0,22	high_impact	2,44	0,57	0,8	57,37	8,66	N	0,27	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14849	14849	T	A	MI.8543	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	103	35	S	T	Tca/Aca	-11,74	0	0	possibly_damaging	0,86	neutral	0,39	neutral	4,46	neutral	-1,57	neutral	-2,23	high_impact	5,09	neutral	0,86	damaging	0,1	neutral	1,72	14,55	0,21	0,45	disease	0,65	disease	0,82	disease	0,65	disease	0,68	4	neutral	0,87	neutral	0,27	deleterious	1	deleterious	0,74	low_impact	-1,47	medium_impact	0,12	high_impact	3,43	0,68	0,85	57,37	8,66	P	0,62	P	0,7	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14849	14849	T	C	MI.8544	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	103	35	S	P	Tca/Cca	-11,74	0	0	probably_damaging	0,98	neutral	0,2	neutral	4,41	deleterious	-3,55	deleterious	-3,71	high_impact	4,75	neutral	0,93	damaging	0,05	deleterious	2,03	16,41	0,05	0,35	disease	0,77	disease	0,92	disease	0,75	disease	0,76	5	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-2,31	medium_impact	-0,1	high_impact	3,12	0,34	0,8	57,37	8,66	P	0,74	P	1	disease_causing_automatic	0	0,12	rs207460004	Pathogenic	Exercise_intolerance,_cardiomyopathy,_and_septooptic_dysplasia	RCV000010323.4	MedGen	.	.	.	.	T14849C	EXIT/Septo-Optic Dysplasia	-	+	Confirmed	3
chrM	14850	14850	C	G	MI.8545	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	104	35	S	W	tCa/tGa	5,69	1	0	probably_damaging	1	neutral	0,19	neutral	4,39	deleterious	-4,41	deleterious	-5,2	high_impact	5,09	neutral	0,89	damaging	0,09	deleterious	4,04	23,7	0,05	0,35	disease	0,94	disease	0,94	disease	0,69	disease	0,81	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,12	high_impact	3,43	0,21	0,8	57,37	8,66	P	0,71	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14850	14850	C	T	MI.8546	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	104	35	S	L	tCa/tTa	5,69	1	0	probably_damaging	0,99	neutral	0,66	neutral	4,47	neutral	-1,51	deleterious	-4,45	high_impact	4,4	neutral	0,88	damaging	0,06	deleterious	2,85	21,6	0,03	0,35	disease	0,7	disease	0,93	disease	0,61	disease	0,72	4	deleterious	0,99	neutral	0,34	deleterious	2	deleterious	0,83	low_impact	-2,59	medium_impact	0,38	high_impact	2,8	0,63	0,8	57,37	8,66	N	0,51	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14852	14852	C	G	MI.8547	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	106	36	L	V	Ctc/Gtc	-11,05	0	0	probably_damaging	0,98	neutral	0,47	neutral	4,4	neutral	-1,5	neutral	-2,18	high_impact	4,21	neutral	0,95	damaging	0,1	neutral	1,59	13,81	0,2	0,45	disease	0,67	disease	0,7	disease	0,64	disease	0,66	3	neutral	0,98	neutral	0,25	deleterious	2	deleterious	0,78	low_impact	-2,31	medium_impact	0,19	high_impact	2,63	0,57	0,8	58,16	8,7	N	0,32	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14852	14852	C	T	MI.8548	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	106	36	L	F	Ctc/Ttc	-11,05	0	0	probably_damaging	1	neutral	0,72	neutral	4,28	deleterious	-3,33	deleterious	-2,95	high_impact	3,83	neutral	0,96	damaging	0,09	deleterious	3,62	23,2	0,13	0,4	disease	0,62	disease	0,82	disease	0,59	disease	0,67	3	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,44	high_impact	2,28	0,62	0,8	58,16	8,7	N	0,21	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14852	14852	C	A	MI.8549	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	106	36	L	I	Ctc/Atc	-11,05	0	0	probably_damaging	0,99	neutral	0,52	neutral	4,46	neutral	-0,98	neutral	-1,43	high_impact	3,61	neutral	0,96	damaging	0,27	deleterious	3,51	23,1	0,23	0,45	disease	0,59	disease	0,77	disease	0,53	disease	0,58	2	deleterious	0,99	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	0,24	high_impact	2,08	0,64	0,8	58,16	8,7	N	0,25	N	0,86	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8927	8927	C	T	MI.855	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	401	134	P	L	cCt/cTt	3,6	0,99	0	probably_damaging	1	deleterious	0	neutral	3,45	deleterious	-3,63	deleterious	-8,99	high_impact	4,26	damaging	0,6	damaging	0,09	deleterious	4,32	24	0,43	0,65	disease	0,81	disease	0,8	disease	0,7	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,6	low_impact	-1,4	high_impact	2,55	0,79	0,9	49,56	8,76	N	0,45	N	0,95	disease_causing	1	0,33	rs28660616	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14853	14853	T	A	MI.8550	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	107	36	L	H	cTc/cAc	-0,04	0	0	probably_damaging	1	neutral	0,49	neutral	4,24	deleterious	-5,33	deleterious	-5,2	high_impact	5,42	neutral	0,93	damaging	0,07	deleterious	4,08	23,7	0,04	0,35	disease	0,96	disease	0,86	disease	0,72	disease	0,82	6	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,21	high_impact	3,73	0,4	0,8	58,16	8,7	P	0,71	P	0,95	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14853	14853	T	G	MI.8551	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	107	36	L	R	cTc/cGc	-0,04	0	0	probably_damaging	1	neutral	0,31	neutral	4,25	deleterious	-4,77	deleterious	-4,46	high_impact	5,07	neutral	0,94	damaging	0,06	deleterious	3,96	23,6	0,02	0,35	disease	0,94	disease	0,91	disease	0,75	disease	0,83	7	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,03	high_impact	3,41	0,22	0,8	58,16	8,7	P	0,74	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14853	14853	T	C	MI.8552	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	107	36	L	P	cTc/cCc	-0,04	0	0	probably_damaging	1	neutral	0,18	neutral	4,24	deleterious	-5,34	deleterious	-5,19	high_impact	5,07	neutral	0,96	damaging	0,06	deleterious	3,73	23,3	0,02	0,35	disease	0,95	disease	0,88	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,14	high_impact	3,41	0,24	0,8	58,16	8,7	P	0,7	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14855	14855	C	T	MI.8553	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	109	37	L	F	Ctt/Ttt	-13,35	0	0	probably_damaging	1	neutral	0,36	neutral	4,26	neutral	-2,99	deleterious	-2,99	high_impact	4,72	neutral	0,95	damaging	0,09	deleterious	3,53	23,1	0,14	0,4	disease	0,75	disease	0,79	disease	0,64	disease	0,68	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,09	high_impact	3,09	0,45	0,8	56,84	8,26	P	0,63	P	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14855	14855	C	G	MI.8554	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	109	37	L	V	Ctt/Gtt	-13,35	0	0	probably_damaging	0,96	neutral	0,27	neutral	4,41	neutral	-0,82	neutral	-2,23	high_impact	4,52	neutral	0,96	damaging	0,12	neutral	1,5	13,29	0,25	0,45	disease	0,56	disease	0,65	disease	0,63	disease	0,66	3	neutral	0,97	neutral	0,16	deleterious	2	deleterious	0,74	low_impact	-2,02	medium_impact	-0,01	high_impact	2,91	0,47	0,8	56,84	8,26	N	0,41	N	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14855	14855	C	A	MI.8555	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	109	37	L	I	Ctt/Att	-13,35	0	0	probably_damaging	0,98	neutral	0,28	neutral	4,31	neutral	-2,01	neutral	-1,48	high_impact	4,32	neutral	0,93	damaging	0,12	deleterious	2,39	18,78	0,3	0,45	disease	0,61	disease	0,74	disease	0,55	disease	0,64	3	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,78	low_impact	-2,31	medium_impact	0	high_impact	2,73	0,59	0,8	56,84	8,26	N	0,37	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14856	14856	T	A	MI.8556	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	110	37	L	H	cTt/cAt	-0,27	0	0	probably_damaging	1	neutral	0,23	neutral	4,23	deleterious	-4,35	deleterious	-5,24	high_impact	5,42	neutral	0,93	damaging	0,08	deleterious	3,87	23,5	0,04	0,35	disease	0,86	disease	0,84	disease	0,72	disease	0,76	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,06	high_impact	3,73	0,34	0,8	56,84	8,26	P	0,67	P	0,95	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14856	14856	T	G	MI.8557	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	110	37	L	R	cTt/cGt	-0,27	0	0	probably_damaging	1	neutral	0,13	neutral	4,24	deleterious	-3,68	deleterious	-4,49	high_impact	5,07	neutral	0,94	damaging	0,06	deleterious	3,88	23,5	0,03	0,35	disease	0,78	disease	0,89	disease	0,74	disease	0,73	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,23	high_impact	3,41	0,26	0,8	56,84	8,26	P	0,71	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14856	14856	T	C	MI.8558	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	110	37	L	P	cTt/cCt	-0,27	0	0	probably_damaging	1	neutral	0,07	neutral	4,23	deleterious	-4,29	deleterious	-5,24	high_impact	4,32	neutral	0,94	damaging	0,06	deleterious	3,68	23,3	0,03	0,35	disease	0,82	disease	0,86	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,39	high_impact	2,73	0,27	0,8	56,84	8,26	N	0,47	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14858	14858	G	T	MI.8559	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	112	38	G	C	Ggc/Tgc	-2,11	0	0	probably_damaging	1	neutral	0,19	neutral	4,52	neutral	-2,16	deleterious	-6,25	high_impact	4,95	neutral	0,91	damaging	0,2	deleterious	3,92	23,5	0,05	0,35	disease	0,88	disease	0,94	disease	0,58	disease	0,72	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,12	high_impact	3,3	0,19	0,8	21,32	40,51	P	0,64	P	0,89	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8929	8929	A	G	MI.856	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	403	135	T	A	Aca/Gca	-14,68	0	0	probably_damaging	0,99	neutral	0,6	neutral	3,91	neutral	0,45	deleterious	-2,93	low_impact	1,05	neutral	0,94	neutral	0,94	deleterious	2,32	18,32	0,56	0,65	neutral	0,35	neutral	0,25	neutral	0,3	neutral	0,46	1	deleterious	0,99	neutral	0,31	neutral	-2	deleterious	0,64	low_impact	-2,65	medium_impact	0,39	medium_impact	-0,2	0,45	0,9	17,7	17,51	N	0,34	N	0,25	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14858	14858	G	A	MI.8560	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	112	38	G	S	Ggc/Agc	-2,11	0	0	probably_damaging	1	neutral	0,43	neutral	4,61	neutral	0,05	deleterious	-4,12	medium_impact	3,02	neutral	0,85	neutral	0,32	deleterious	3,9	23,5	0,11	0,4	disease	0,62	disease	0,84	neutral	0,5	disease	0,6	2	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,82	low_impact	-3,53	medium_impact	0,16	medium_impact	1,55	0,57	0,8	21,32	40,51	N	0,26	N	0,72	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14858	14858	G	C	MI.8561	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	112	38	G	R	Ggc/Cgc	-2,11	0	0	probably_damaging	1	neutral	0,32	neutral	4,54	neutral	-1,63	deleterious	-5,59	high_impact	4,74	neutral	0,9	damaging	0,21	deleterious	3,68	23,3	0,04	0,35	disease	0,85	disease	0,92	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,05	high_impact	3,11	0,51	0,8	21,32	40,51	P	0,65	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14859	14859	G	A	MI.8562	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	113	38	G	D	gGc/gAc	5	1	0,01	probably_damaging	1	neutral	0,19	neutral	4,52	neutral	-2,62	deleterious	-4,95	high_impact	5,29	neutral	0,86	damaging	0,27	deleterious	3,6	23,2	0,05	0,35	disease	0,84	disease	0,91	disease	0,69	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,12	high_impact	3,61	0,13	0,8	21,32	40,51	P	0,74	P	0,9	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14859	14859	G	C	MI.8563	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	113	38	G	A	gGc/gCc	5	1	0,01	probably_damaging	0,99	neutral	0,48	neutral	4,69	neutral	1,33	deleterious	-4,03	medium_impact	2,94	neutral	0,95	neutral	0,59	neutral	1,58	13,76	0,13	0,4	neutral	0,39	disease	0,75	neutral	0,49	neutral	0,41	2	deleterious	0,99	neutral	0,25	deleterious	1	deleterious	0,77	low_impact	-2,59	medium_impact	0,2	medium_impact	1,48	0,4	0,8	21,32	40,51	N	0,51	P	0,38	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14859	14859	G	T	MI.8564	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	113	38	G	V	gGc/gTc	5	1	0,01	probably_damaging	1	neutral	0,51	neutral	4,64	neutral	0,87	deleterious	-6,21	high_impact	3,98	neutral	0,87	neutral	0,36	deleterious	3,61	23,2	0,05	0,35	disease	0,77	disease	0,89	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,23	high_impact	2,42	0,12	0,8	21,32	40,51	N	0,47	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14861	14861	G	C	MI.8565	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	115	39	A	P	Gcc/Ccc	-13,35	0	0,01	possibly_damaging	0,6	neutral	0,2	neutral	4,57	neutral	-2,08	neutral	-1,67	medium_impact	2,38	neutral	0,94	neutral	0,4	deleterious	3,47	23	0,05	0,35	disease	0,63	disease	0,82	disease	0,62	disease	0,77	5	neutral	0,8	neutral	0,3	NA	0	deleterious	0,66	medium_impact	-0,9	medium_impact	-0,1	medium_impact	0,97	0,48	0,8	24,74	31,68	N	0,31	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14861	14861	G	T	MI.8566	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	115	39	A	S	Gcc/Tcc	-13,35	0	0,01	benign	0,22	neutral	0,44	neutral	4,63	neutral	-0,43	neutral	-0,88	medium_impact	1,96	neutral	0,94	neutral	0,65	deleterious	1,96	15,96	0,22	0,45	neutral	0,4	neutral	0,38	neutral	0,47	neutral	0,47	1	neutral	0,47	deleterious	0,61	neutral	-3	neutral	0,22	medium_impact	-0,22	medium_impact	0,17	medium_impact	0,59	0,32	0,8	24,74	31,68	N	0,34	N	0,54	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14861	14861	G	A	MI.8567	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	115	39	A	T	Gcc/Acc	-13,35	0	0,01	benign	0,01	neutral	0,42	neutral	4,67	neutral	-0,36	neutral	-0,2	neutral_impact	0,59	neutral	0,99	neutral	0,77	deleterious	2,33	18,33	0,23	0,45	neutral	0,34	neutral	0,31	neutral	0,39	neutral	0,46	1	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,1	medium_impact	1,13	medium_impact	0,15	medium_impact	-0,66	0,7	0,85	24,74	31,68	N	0,4	N	0,43	polymorphism	1	0,01	rs2853505	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14862	14862	C	A	MI.8568	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	116	39	A	D	gCc/gAc	-3,71	0	0	possibly_damaging	0,52	neutral	0,21	neutral	4,56	neutral	0,15	neutral	-2,24	medium_impact	2,93	neutral	0,93	neutral	0,5	deleterious	4,17	23,8	0,03	0,35	disease	0,7	disease	0,7	disease	0,63	disease	0,72	4	neutral	0,77	neutral	0,35	NA	0	deleterious	0,59	medium_impact	-0,76	medium_impact	-0,09	medium_impact	1,47	0,45	0,8	24,74	31,68	N	0,37	N	0,63	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14862	14862	C	G	MI.8569	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	116	39	A	G	gCc/gGc	-3,71	0	0	benign	0,22	neutral	0,41	neutral	4,58	neutral	-1,52	neutral	-2,29	low_impact	1,89	neutral	0,93	neutral	0,61	deleterious	2,22	17,66	0,21	0,45	disease	0,55	neutral	0,39	neutral	0,48	disease	0,61	2	neutral	0,51	deleterious	0,6	neutral	-6	neutral	0,27	medium_impact	-0,22	medium_impact	0,14	medium_impact	0,52	0,54	0,8	24,74	31,68	N	0,32	N	0,48	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8929	8929	A	C	MI.857	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	403	135	T	P	Aca/Cca	-14,68	0	0	probably_damaging	1	neutral	0,27	neutral	3,89	neutral	-0,56	deleterious	-4,17	low_impact	1,06	neutral	0,9	neutral	0,7	deleterious	2,46	19,24	0,2	0,65	disease	0,69	disease	0,64	neutral	0,27	neutral	0,5	0	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,75	low_impact	-3,6	medium_impact	0,05	medium_impact	-0,19	0,46	0,9	17,7	17,51	N	0,39	N	0,93	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14862	14862	C	T	MI.8570	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	116	39	A	V	gCc/gTc	-3,71	0	0	benign	0,22	neutral	0,51	neutral	4,77	neutral	0,21	neutral	1,48	neutral_impact	-0,43	neutral	0,98	neutral	0,9	deleterious	2,2	17,49	0,2	0,45	neutral	0,14	neutral	0,28	neutral	0,33	neutral	0,42	2	neutral	0,39	deleterious	0,65	neutral	-6	neutral	0,21	medium_impact	-0,22	medium_impact	0,23	low_impact	-1,58	0,75	0,85	24,74	31,68	N	0,35	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14864	14864	T	G	MI.8571	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	118	40	C	G	Tgc/Ggc	-9,22	0	0	probably_damaging	1	neutral	0,46	neutral	4,51	neutral	-2,57	deleterious	-8,78	high_impact	4,62	neutral	0,97	neutral	0,49	deleterious	3,15	22,6	0,1	0,4	disease	0,83	disease	0,91	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,18	high_impact	3	0,26	0,8	59,47	8,73	N	0,57	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14864	14864	T	C	MI.8572	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	118	40	C	R	Tgc/Cgc	-9,22	0	0	probably_damaging	1	neutral	0,24	neutral	4,51	neutral	-2,63	deleterious	-8,71	high_impact	4,76	neutral	0,93	neutral	0,38	deleterious	3,33	22,9	0,05	0,35	disease	0,83	disease	0,96	disease	0,77	disease	0,78	6	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,05	high_impact	3,13	0,12	0,8	59,47	8,73	P	0,76	P	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	T14864C	MELAS	-	+	Confirmed	1
chrM	14864	14864	T	A	MI.8573	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	118	40	C	S	Tgc/Agc	-9,22	0	0	probably_damaging	1	neutral	0,36	neutral	4,57	neutral	-0,88	deleterious	-7,26	medium_impact	3,38	neutral	0,94	neutral	0,47	deleterious	3,34	22,9	0,12	0,4	disease	0,73	disease	0,91	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,86	low_impact	-3,53	medium_impact	0,09	medium_impact	1,88	0,33	0,8	59,47	8,73	N	0,38	N	0,94	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14865	14865	G	A	MI.8574	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	119	40	C	Y	tGc/tAc	5,69	1	0	probably_damaging	1	neutral	0,57	neutral	4,52	neutral	-2,13	deleterious	-7,98	high_impact	4,76	neutral	0,94	neutral	0,41	deleterious	3,31	22,9	0,07	0,35	disease	0,8	disease	0,96	disease	0,71	disease	0,77	5	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,29	high_impact	3,13	0,32	0,8	59,47	8,73	P	0,65	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14865	14865	G	T	MI.8575	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	119	40	C	F	tGc/tTc	5,69	1	0	probably_damaging	1	neutral	0,62	neutral	4,56	neutral	-1,08	deleterious	-7,95	medium_impact	3,25	neutral	0,95	neutral	0,45	deleterious	3,55	23,1	0,07	0,35	disease	0,69	disease	0,96	disease	0,67	disease	0,77	5	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,88	low_impact	-3,53	medium_impact	0,34	medium_impact	1,76	0,28	0,8	59,47	8,73	N	0,49	N	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14865	14865	G	C	MI.8576	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	119	40	C	S	tGc/tCc	5,69	1	0	probably_damaging	1	neutral	0,36	neutral	4,57	neutral	-0,88	deleterious	-7,26	medium_impact	3,38	neutral	0,94	neutral	0,47	deleterious	2,86	21,7	0,12	0,4	disease	0,73	disease	0,91	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,86	low_impact	-3,53	medium_impact	0,09	medium_impact	1,88	0,33	0,8	59,47	8,73	N	0,54	P	0,94	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14866	14866	C	G	MI.8577	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	120	40	C	W	tgC/tgG	7,07	1	0	probably_damaging	1	neutral	0,1	neutral	4,5	deleterious	-3,93	deleterious	-7,98	high_impact	4,27	neutral	0,94	neutral	0,39	deleterious	4,1	23,7	0,06	0,35	disease	0,92	disease	0,96	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,3	high_impact	2,68	0,27	0,8	59,47	8,73	P	0,61	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14866	14866	C	A	MI.8578	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	120	40	C	W	tgC/tgA	7,07	1	0	probably_damaging	1	neutral	0,1	neutral	4,5	deleterious	-3,93	deleterious	-7,98	high_impact	4,27	neutral	0,94	neutral	0,39	deleterious	4,43	24,2	0,06	0,35	disease	0,92	disease	0,96	disease	0,74	disease	0,69	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,3	high_impact	2,68	0,27	0,8	59,47	8,73	P	0,61	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14867	14867	C	A	MI.8579	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	121	41	L	M	Ctg/Atg	-0,73	0	0,01	probably_damaging	1	neutral	0,14	neutral	4,17	deleterious	-4,04	neutral	-1,52	high_impact	4,07	neutral	0,94	damaging	0,1	deleterious	3,45	23	0,14	0,4	disease	0,7	disease	0,72	disease	0,59	disease	0,64	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	-0,21	high_impact	2,5	0,42	0,8	58,95	8,74	N	0,41	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8929	8929	A	T	MI.858	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	403	135	T	S	Aca/Tca	-14,68	0	0	probably_damaging	0,99	neutral	0,51	neutral	3,89	neutral	-0,45	deleterious	-2,51	low_impact	1,69	neutral	0,86	neutral	0,73	deleterious	3,4	23	0,52	0,65	neutral	0,41	neutral	0,36	neutral	0,3	neutral	0,48	1	deleterious	0,99	neutral	0,26	neutral	-2	deleterious	0,67	low_impact	-2,65	medium_impact	0,3	medium_impact	0,35	0,61	0,9	17,7	17,51	N	0,32	N	0,16	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14867	14867	C	G	MI.8580	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	121	41	L	V	Ctg/Gtg	-0,73	0	0,01	probably_damaging	0,98	neutral	0,23	neutral	4,21	deleterious	-3,31	neutral	-2,29	high_impact	4,79	neutral	0,95	damaging	0,11	neutral	1,6	13,85	0,15	0,45	disease	0,68	disease	0,71	disease	0,62	disease	0,65	3	deleterious	0,98	neutral	0,13	deleterious	2	deleterious	0,79	low_impact	-2,31	medium_impact	-0,06	high_impact	3,16	0,51	0,8	58,95	8,74	P	0,65	P	0,91	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14868	14868	T	A	MI.8581	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	122	41	L	Q	cTg/cAg	-3,03	0	0	probably_damaging	1	neutral	0,15	neutral	4,13	deleterious	-5,89	deleterious	-4,58	high_impact	5,48	neutral	0,94	damaging	0,07	deleterious	3,97	23,6	0,03	0,35	disease	0,93	disease	0,88	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,19	high_impact	3,78	0,23	0,8	58,95	8,74	P	0,65	P	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14868	14868	T	G	MI.8582	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	122	41	L	R	cTg/cGg	-3,03	0	0	probably_damaging	1	neutral	0,07	neutral	4,13	deleterious	-5,85	deleterious	-4,58	high_impact	5,48	neutral	0,94	damaging	0,06	deleterious	3,96	23,6	0,02	0,35	disease	0,94	disease	0,93	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,39	high_impact	3,78	0,15	0,8	58,95	8,74	P	0,68	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14868	14868	T	C	MI.8583	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	122	41	L	P	cTg/cCg	-3,03	0	0	probably_damaging	1	deleterious	0,04	neutral	4,12	deleterious	-6,4	deleterious	-5,34	high_impact	4,58	neutral	0,94	damaging	0,05	deleterious	3,66	23,2	0,02	0,35	disease	0,95	disease	0,88	disease	0,76	disease	0,74	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,89	low_impact	-3,53	medium_impact	-0,53	high_impact	2,97	0,25	0,8	58,95	8,74	N	0,51	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14870	14870	A	T	MI.8584	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	124	42	I	F	Atc/Ttc	-1,88	0	0	benign	0,2	neutral	0,35	neutral	4,47	neutral	-2,12	deleterious	-2,55	medium_impact	2,68	neutral	0,95	neutral	0,5	deleterious	1,8	15,01	0,13	0,4	neutral	0,42	disease	0,81	disease	0,59	disease	0,67	3	neutral	0,58	deleterious	0,58	neutral	-3	neutral	0,42	medium_impact	-0,17	medium_impact	0,08	medium_impact	1,24	0,47	0,8	18,42	22,46	N	0,32	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14870	14870	A	G	MI.8585	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	124	42	I	V	Atc/Gtc	-1,88	0	0	benign	0	neutral	0,17	neutral	4,67	neutral	-0,04	neutral	-0,4	low_impact	0,88	neutral	0,99	neutral	0,93	neutral	-0,43	0,34	0,34	0,5	neutral	0,19	neutral	0,27	neutral	0,35	neutral	0,42	2	neutral	0,83	deleterious	0,59	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	-0,15	medium_impact	-0,39	0,46	0,8	18,42	22,46	N	0,48	N	0,68	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14870	14870	A	C	MI.8586	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	124	42	I	L	Atc/Ctc	-1,88	0	0	benign	0,01	neutral	1	neutral	4,6	neutral	-0,49	neutral	-1,08	low_impact	1,56	neutral	0,97	neutral	0,72	deleterious	0,67	8,62	0,23	0,45	neutral	0,34	disease	0,68	neutral	0,38	neutral	0,36	3	neutral	0,01	deleterious	1	neutral	-6	neutral	0,15	medium_impact	1,13	high_impact	1,85	medium_impact	0,22	0,44	0,8	18,42	22,46	N	0,22	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14871	14871	T	C	MI.8587	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	125	42	I	T	aTc/aCc	-1,65	0	0	benign	0	neutral	0,37	neutral	4,48	neutral	-1,74	deleterious	-2,84	medium_impact	2,06	neutral	0,98	neutral	0,9	deleterious	0,33	5,98	0,08	0,35	neutral	0,48	disease	0,62	neutral	0,43	neutral	0,35	3	neutral	0,63	deleterious	0,69	neutral	-3	neutral	0,16	high_impact	2,07	medium_impact	0,1	medium_impact	0,68	0,35	0,8	18,42	22,46	N	0,36	N	0,78	polymorphism	1	0,03	rs28660155	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14871	14871	T	G	MI.8588	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	125	42	I	S	aTc/aGc	-1,65	0	0	benign	0,14	neutral	0,21	neutral	4,45	neutral	-2,46	deleterious	-3,51	medium_impact	2,76	neutral	0,97	neutral	0,57	deleterious	2,4	18,82	0,05	0,35	disease	0,56	disease	0,83	disease	0,57	disease	0,66	3	neutral	0,76	deleterious	0,54	neutral	-3	neutral	0,34	medium_impact	0	medium_impact	-0,09	medium_impact	1,31	0,27	0,8	18,42	22,46	N	0,36	N	0,7	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14871	14871	T	A	MI.8589	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	125	42	I	N	aTc/aAc	-1,65	0	0	benign	0,22	neutral	0,06	neutral	4,42	deleterious	-3,96	deleterious	-4,39	high_impact	4,55	neutral	0,93	neutral	0,48	deleterious	2,65	20,5	0,1	0,4	disease	0,73	disease	0,86	disease	0,59	disease	0,69	4	neutral	0,93	neutral	0,42	neutral	-2	deleterious	0,54	medium_impact	-0,22	medium_impact	-0,43	high_impact	2,94	0,29	0,8	18,42	22,46	N	0,5	N	0,88	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8930	8930	C	A	MI.859	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	404	135	T	K	aCa/aAa	-0,8	0	0	probably_damaging	1	neutral	0,34	neutral	3,88	neutral	0,33	deleterious	-3,99	medium_impact	2,4	neutral	0,85	neutral	0,46	deleterious	4,36	24,1	0,25	0,65	disease	0,72	disease	0,72	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	0,13	medium_impact	0,96	0,7	0,9	17,7	17,51	N	0,25	N	0,83	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14872	14872	C	A	MI.8590	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	126	42	I	M	atC/atA	-0,73	0	0,03	benign	0,35	neutral	0,13	neutral	4,48	neutral	-1,94	neutral	-1,5	low_impact	1,01	neutral	0,93	neutral	0,89	deleterious	0,69	8,73	0,25	0,45	neutral	0,4	neutral	0,47	neutral	0,35	neutral	0,44	1	neutral	0,85	neutral	0,39	neutral	-6	neutral	0,29	medium_impact	-0,48	medium_impact	-0,23	medium_impact	-0,28	0,58	0,8	18,42	22,46	N	0,43	N	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14872	14872	C	G	MI.8591	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	126	42	I	M	atC/atG	-0,73	0	0,03	benign	0,35	neutral	0,13	neutral	4,48	neutral	-1,94	neutral	-1,5	low_impact	1,01	neutral	0,93	neutral	0,89	deleterious	0,22	4,88	0,25	0,45	neutral	0,4	neutral	0,47	neutral	0,35	neutral	0,44	1	neutral	0,85	neutral	0,39	neutral	-6	neutral	0,29	medium_impact	-0,48	medium_impact	-0,23	medium_impact	-0,28	0,58	0,8	18,42	22,46	N	0,42	N	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14873	14873	C	G	MI.8592	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	127	43	L	V	Ctc/Gtc	-14,04	0	0	benign	0,04	neutral	0,42	neutral	4,67	neutral	-0,25	neutral	0,15	neutral_impact	0,5	neutral	0,97	neutral	0,87	deleterious	-0,03	2,29	0,22	0,45	neutral	0,24	neutral	0,24	neutral	0,28	neutral	0,44	1	neutral	0,55	deleterious	0,69	neutral	-6	neutral	0,13	medium_impact	0,56	medium_impact	0,15	medium_impact	-0,74	0,61	0,8	22,11	23,68	N	0,45	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14873	14873	C	T	MI.8593	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	127	43	L	F	Ctc/Ttc	-14,04	0	0	possibly_damaging	0,47	neutral	0,37	neutral	4,52	neutral	-1,96	neutral	-1,43	low_impact	1,92	neutral	0,97	neutral	0,65	deleterious	3,58	23,2	0,17	0,45	neutral	0,37	disease	0,51	neutral	0,44	neutral	0,48	0	neutral	0,59	neutral	0,45	neutral	-3	deleterious	0,56	medium_impact	-0,68	medium_impact	0,1	medium_impact	0,55	0,56	0,8	22,11	23,68	N	0,42	N	0,53	polymorphism	1	0,02	rs879056276	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14873	14873	C	A	MI.8594	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	127	43	L	I	Ctc/Atc	-14,04	0	0	benign	0,02	neutral	0,55	neutral	4,72	neutral	0,22	neutral	0,05	neutral_impact	-0,66	neutral	0,95	neutral	0,95	neutral	-0,38	0,42	0,24	0,45	neutral	0,15	neutral	0,07	neutral	0,21	neutral	0,21	6	neutral	0,43	deleterious	0,77	neutral	-6	neutral	0,09	medium_impact	0,85	medium_impact	0,27	low_impact	-1,79	0,56	0,8	22,11	23,68	N	0,42	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14874	14874	T	G	MI.8595	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	128	43	L	R	cTc/cGc	-2,57	0	0	possibly_damaging	0,84	neutral	0,14	neutral	4,46	deleterious	-3,49	neutral	-1,92	high_impact	3,76	neutral	0,94	neutral	0,49	deleterious	3,93	23,5	0,02	0,35	disease	0,63	disease	0,8	disease	0,63	disease	0,74	5	neutral	0,93	neutral	0,15	deleterious	1	deleterious	0,78	low_impact	-1,4	medium_impact	-0,21	high_impact	2,22	0,31	0,8	22,11	23,68	N	0,46	N	0,87	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14874	14874	T	A	MI.8596	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	128	43	L	H	cTc/cAc	-2,57	0	0	probably_damaging	0,92	neutral	0,22	neutral	4,46	deleterious	-4,02	neutral	-2,46	high_impact	3,76	neutral	0,93	neutral	0,5	deleterious	3,96	23,6	0,04	0,35	disease	0,71	disease	0,59	disease	0,58	disease	0,68	4	neutral	0,94	neutral	0,15	deleterious	2	deleterious	0,73	low_impact	-1,72	medium_impact	-0,08	high_impact	2,22	0,28	0,8	22,11	23,68	N	0,46	N	0,72	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14874	14874	T	C	MI.8597	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	128	43	L	P	cTc/cCc	-2,57	0	0	probably_damaging	0,95	neutral	0,08	neutral	4,46	deleterious	-4,07	neutral	-2,06	high_impact	3,76	neutral	0,93	neutral	0,39	deleterious	3,7	23,3	0,02	0,35	disease	0,71	disease	0,84	disease	0,63	disease	0,77	5	deleterious	0,98	neutral	0,07	deleterious	2	deleterious	0,83	low_impact	-1,92	medium_impact	-0,35	high_impact	2,22	0,25	0,8	22,11	23,68	N	0,43	N	0,94	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14876	14876	C	A	MI.8598	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	130	44	Q	K	Caa/Aaa	-20	0	0	probably_damaging	0,98	neutral	0,21	neutral	4,34	neutral	-2,06	deleterious	-3,16	high_impact	5,55	neutral	0,84	damaging	0,1	deleterious	1,95	15,91	0,16	0,45	disease	0,71	disease	0,88	disease	0,77	disease	0,74	5	deleterious	0,99	neutral	0,12	deleterious	2	deleterious	0,85	low_impact	-2,31	medium_impact	-0,09	high_impact	3,85	0,59	0,8	57,89	8,73	P	0,7	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14876	14876	C	G	MI.8599	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	130	44	Q	E	Caa/Gaa	-20	0	0	probably_damaging	0,96	neutral	0,19	neutral	4,37	neutral	-2,21	neutral	-2,37	high_impact	5,21	neutral	0,83	damaging	0,11	neutral	1,12	11,33	0,27	0,45	disease	0,71	disease	0,78	disease	0,74	disease	0,7	4	neutral	0,97	neutral	0,12	deleterious	2	deleterious	0,82	low_impact	-2,02	medium_impact	-0,12	high_impact	3,54	0,64	0,8	57,89	8,73	P	0,66	P	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8564	8564	C	T	MI.86	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	38	13	T	M	aCa/aTa	0,13	0	0	probably_damaging	1	neutral	0,07	neutral	4,51	neutral	-1,96	deleterious	-2,94	low_impact	1,9	neutral	0,91	neutral	0,93	deleterious	8,54	35	0,41	0,65	neutral	0,49	disease	0,68	disease	0,63	disease	0,53	1	deleterious	1	neutral	0,04	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	-0,34	medium_impact	0,53	0,77	0,9	15,49	16,77	N	0,43	N	0,85	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8930	8930	C	T	MI.860	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	404	135	T	M	aCa/aTa	-0,8	0	0	probably_damaging	1	neutral	0,26	neutral	3,88	neutral	-0,97	deleterious	-3,19	low_impact	1,58	neutral	0,94	neutral	0,71	deleterious	2,91	21,9	0,33	0,65	disease	0,6	neutral	0,43	neutral	0,32	disease	0,6	2	deleterious	1	neutral	0,13	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,04	medium_impact	0,26	0,69	0,9	17,7	17,51	N	0,41	N	0,5	polymorphism	1	0,06	.	.	.	.	.	pituitary adenoma	.	.	.	.	.	.	.	.	.
chrM	14877	14877	A	T	MI.8600	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	131	44	Q	L	cAa/cTa	7,07	1	0	probably_damaging	0,98	neutral	1	neutral	4,41	neutral	-0,7	deleterious	-5,53	high_impact	4,66	neutral	0,86	damaging	0,09	deleterious	1,85	15,29	0,06	0,35	disease	0,88	disease	0,9	disease	0,68	disease	0,66	3	deleterious	0,98	deleterious	0,51	deleterious	2	deleterious	0,87	low_impact	-2,31	high_impact	1,85	high_impact	3,04	0,19	0,8	57,89	8,73	P	0,56	P	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14877	14877	A	C	MI.8601	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	131	44	Q	P	cAa/cCa	7,07	1	0	probably_damaging	1	neutral	0,15	neutral	4,27	neutral	-1,17	deleterious	-4,73	high_impact	4,86	neutral	0,83	damaging	0,07	deleterious	2,79	21,3	0,04	0,35	disease	0,9	disease	0,89	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,19	high_impact	3,22	0,33	0,8	57,89	8,73	P	0,77	P	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14877	14877	A	G	MI.8602	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	131	44	Q	R	cAa/cGa	7,07	1	0	probably_damaging	0,99	neutral	0,25	neutral	4,31	neutral	-2,42	deleterious	-3,16	high_impact	5,55	neutral	0,84	damaging	0,1	neutral	1,54	13,51	0,17	0,45	disease	0,75	disease	0,88	disease	0,78	disease	0,73	5	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,88	low_impact	-2,59	medium_impact	-0,04	high_impact	3,85	0,34	0,8	57,89	8,73	P	0,78	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14878	14878	A	T	MI.8603	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	132	44	Q	H	caA/caT	6,61	1	0	probably_damaging	1	neutral	0,44	neutral	4,28	deleterious	-3,19	deleterious	-3,94	high_impact	5,21	neutral	0,81	damaging	0,08	neutral	1,74	14,66	0,16	0,45	disease	0,9	disease	0,82	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,17	high_impact	3,54	0,7	0,85	57,89	8,73	P	0,81	P	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14878	14878	A	C	MI.8604	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	132	44	Q	H	caA/caC	6,61	1	0	probably_damaging	1	neutral	0,44	neutral	4,28	deleterious	-3,19	deleterious	-3,94	high_impact	5,21	neutral	0,81	damaging	0,08	neutral	1,58	13,72	0,16	0,45	disease	0,9	disease	0,82	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,17	high_impact	3,54	0,7	0,85	57,89	8,73	P	0,8	P	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14879	14879	A	T	MI.8605	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	133	45	I	F	Atc/Ttc	1,33	1	0	benign	0,43	neutral	0,86	neutral	4,31	deleterious	-3,12	deleterious	-3,11	high_impact	4,12	neutral	0,85	neutral	0,36	neutral	1,78	14,86	0,08	0,35	disease	0,77	disease	0,83	disease	0,64	disease	0,67	3	neutral	0,32	deleterious	0,72	neutral	-2	deleterious	0,64	medium_impact	-0,62	medium_impact	0,65	high_impact	2,55	0,61	0,8	55,53	8,5	N	0,37	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14879	14879	A	C	MI.8606	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	133	45	I	L	Atc/Ctc	1,33	1	0	benign	0,04	neutral	0,89	neutral	4,42	neutral	-0,99	neutral	-1,51	medium_impact	1,99	neutral	0,84	neutral	0,34	neutral	1,58	13,74	0,31	0,45	neutral	0,39	disease	0,69	neutral	0,41	neutral	0,2	6	neutral	0,04	deleterious	0,93	neutral	-3	neutral	0,21	medium_impact	0,56	medium_impact	0,71	medium_impact	0,61	0,61	0,8	55,53	8,5	N	0,34	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14879	14879	A	G	MI.8607	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	133	45	I	V	Atc/Gtc	1,33	1	0	benign	0,02	neutral	0,53	neutral	4,58	neutral	-0,88	neutral	-0,66	medium_impact	2,73	neutral	0,87	neutral	0,6	deleterious	0,83	9,66	0,48	0,55	neutral	0,42	neutral	0,45	neutral	0,45	neutral	0,39	2	neutral	0,45	deleterious	0,76	neutral	-3	neutral	0,17	medium_impact	0,85	medium_impact	0,25	medium_impact	1,29	0,61	0,8	55,53	8,5	N	0,46	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14880	14880	T	C	MI.8608	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	134	45	I	T	aTc/aCc	6,61	1	0	benign	0,01	neutral	0,42	neutral	4,32	deleterious	-3,26	deleterious	-3,71	medium_impact	3,11	neutral	0,9	neutral	0,44	neutral	1,64	14,07	0,05	0,35	disease	0,77	disease	0,7	disease	0,55	neutral	0,32	4	neutral	0,57	deleterious	0,71	neutral	-3	neutral	0,27	medium_impact	1,13	medium_impact	0,15	medium_impact	1,63	0,37	0,8	55,53	8,5	P	0,59	P	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14880	14880	T	G	MI.8609	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	134	45	I	S	aTc/aGc	6,61	1	0	benign	0,18	neutral	0,41	neutral	4,28	deleterious	-4,33	deleterious	-4,58	high_impact	4,98	neutral	0,84	neutral	0,38	deleterious	2,61	20,3	0,03	0,35	disease	0,88	disease	0,85	disease	0,62	disease	0,67	3	neutral	0,51	deleterious	0,62	neutral	-2	deleterious	0,57	medium_impact	-0,12	medium_impact	0,14	high_impact	3,33	0,29	0,8	55,53	8,5	P	0,67	P	0,98	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8932	8932	C	G	MI.861	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	406	136	P	A	Ccc/Gcc	-12,6	0	0	probably_damaging	1	neutral	0,53	neutral	4,48	neutral	-0,99	deleterious	-4,96	neutral_impact	0,74	neutral	0,89	neutral	0,78	deleterious	1,9	15,59	0,34	0,65	disease	0,57	neutral	0,24	neutral	0,32	disease	0,55	1	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,71	low_impact	-3,6	medium_impact	0,32	medium_impact	-0,46	0,77	0,9	18,14	17,08	N	0,38	N	0,56	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14880	14880	T	A	MI.8610	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	134	45	I	N	aTc/aAc	6,61	1	0	benign	0,38	neutral	0,32	neutral	4,26	deleterious	-5,23	deleterious	-5,38	high_impact	4,98	neutral	0,83	neutral	0,36	deleterious	4,09	23,7	0,07	0,35	disease	0,93	disease	0,86	disease	0,62	disease	0,66	3	neutral	0,62	deleterious	0,47	neutral	-2	deleterious	0,66	medium_impact	-0,53	medium_impact	0,05	high_impact	3,33	0,46	0,8	55,53	8,5	P	0,65	P	0,99	polymorphism	1	0,18	.	.	.	.	.	MNGIE fibroblasts	.	.	.	.	.	.	.	.	.
chrM	14881	14881	C	G	MI.8611	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	135	45	I	M	atC/atG	4,54	1	0	possibly_damaging	0,62	neutral	0,31	neutral	4,29	deleterious	-3,83	neutral	-2,21	medium_impact	3,23	neutral	0,84	neutral	0,35	neutral	1,54	13,53	0,16	0,45	disease	0,57	disease	0,73	disease	0,56	disease	0,5	0	neutral	0,72	neutral	0,35	NA	0	deleterious	0,62	medium_impact	-0,93	medium_impact	0,03	medium_impact	1,74	0,66	0,8	55,53	8,5	N	0,48	N	0,83	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14881	14881	C	A	MI.8612	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	135	45	I	M	atC/atA	4,54	1	0	possibly_damaging	0,62	neutral	0,31	neutral	4,29	deleterious	-3,83	neutral	-2,21	medium_impact	3,23	neutral	0,84	neutral	0,35	deleterious	1,96	15,97	0,16	0,45	disease	0,57	disease	0,73	disease	0,56	disease	0,5	0	neutral	0,72	neutral	0,35	NA	0	deleterious	0,62	medium_impact	-0,93	medium_impact	0,03	medium_impact	1,74	0,66	0,8	55,53	8,5	N	0,48	N	0,83	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14882	14882	A	G	MI.8613	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	136	46	T	A	Acc/Gcc	-2,57	0	0	benign	0,03	neutral	0,29	neutral	4,74	neutral	0,99	neutral	-0,3	neutral_impact	-0,4	neutral	0,93	neutral	0,88	deleterious	0,35	6,15	0,31	0,45	neutral	0,36	neutral	0,25	neutral	0,33	neutral	0,43	1	neutral	0,69	deleterious	0,63	neutral	-6	neutral	0,13	medium_impact	0,68	medium_impact	0,01	low_impact	-1,56	0,35	0,8	25	38,64	N	0,38	N	0,18	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14882	14882	A	C	MI.8614	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	136	46	T	P	Acc/Ccc	-2,57	0	0	benign	0,38	neutral	0,08	neutral	4,65	neutral	-2,05	neutral	-1,88	medium_impact	2,63	neutral	0,84	neutral	0,45	deleterious	2,94	22	0,05	0,35	disease	0,7	disease	0,83	disease	0,63	disease	0,76	5	neutral	0,91	neutral	0,35	neutral	-3	deleterious	0,53	medium_impact	-0,53	medium_impact	-0,35	medium_impact	1,19	0,4	0,8	25	38,64	N	0,31	N	0,77	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14882	14882	A	T	MI.8615	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	136	46	T	S	Acc/Tcc	-2,57	0	0	benign	0,1	neutral	0,28	neutral	4,69	neutral	0,06	neutral	-0,99	low_impact	0,94	neutral	0,9	neutral	0,71	neutral	1,41	12,82	0,45	0,55	disease	0,5	neutral	0,35	neutral	0,48	neutral	0,21	6	neutral	0,68	deleterious	0,59	neutral	-6	neutral	0,2	medium_impact	0,16	medium_impact	0	medium_impact	-0,34	0,54	0,8	25	38,64	N	0,41	N	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14883	14883	C	G	MI.8616	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	137	46	T	S	aCc/aGc	-6,7	0	0	benign	0,1	neutral	0,28	neutral	4,69	neutral	0,06	neutral	-0,99	low_impact	0,94	neutral	0,9	neutral	0,71	neutral	1,61	13,9	0,45	0,55	disease	0,5	neutral	0,35	neutral	0,48	neutral	0,21	6	neutral	0,68	deleterious	0,59	neutral	-6	neutral	0,2	medium_impact	0,16	medium_impact	0	medium_impact	-0,34	0,54	0,8	25	38,64	N	0,39	N	0,44	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14883	14883	C	T	MI.8617	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	137	46	T	I	aCc/aTc	-6,7	0	0	benign	0	neutral	0,75	neutral	4,97	neutral	2,8	neutral	1,94	neutral_impact	-1,43	neutral	0,95	neutral	0,97	neutral	1,57	13,68	0,17	0,45	neutral	0,14	neutral	0,3	neutral	0,3	neutral	0,43	1	neutral	0,25	deleterious	0,88	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,48	low_impact	-2,49	0,63	0,8	25	38,64	N	0,28	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14883	14883	C	A	MI.8618	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	137	46	T	N	aCc/aAc	-6,7	0	0	benign	0,38	neutral	0,11	neutral	4,65	neutral	-1,75	neutral	-1,85	medium_impact	2,63	neutral	0,83	neutral	0,63	deleterious	1,94	15,86	0,31	0,45	disease	0,67	disease	0,64	disease	0,51	disease	0,54	1	neutral	0,87	neutral	0,37	neutral	-3	deleterious	0,45	medium_impact	-0,53	medium_impact	-0,27	medium_impact	1,19	0,53	0,8	25	38,64	N	0,34	N	0,57	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14885	14885	A	T	MI.8619	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	139	47	T	S	Aca/Tca	-9,22	0	0	probably_damaging	0,98	neutral	0,58	neutral	3,86	neutral	-2,26	deleterious	-3,17	medium_impact	2,32	neutral	0,98	neutral	0,44	neutral	1,47	13,18	0,35	0,5	disease	0,55	disease	0,74	disease	0,54	neutral	0,46	1	neutral	0,97	neutral	0,3	deleterious	1	deleterious	0,78	low_impact	-2,31	medium_impact	0,3	medium_impact	0,91	0,56	0,8	58,68	8,72	N	0,28	N	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8932	8932	C	A	MI.862	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	406	136	P	T	Ccc/Acc	-12,6	0	0	probably_damaging	1	neutral	0,4	neutral	4,36	neutral	-2,75	deleterious	-5,02	medium_impact	2,88	neutral	0,88	neutral	0,64	deleterious	2,62	20,3	0,29	0,65	disease	0,72	neutral	0,42	neutral	0,33	disease	0,64	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,75	low_impact	-3,6	medium_impact	0,19	medium_impact	1,37	0,8	0,9	18,14	17,08	N	0,41	N	0,68	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14885	14885	A	G	MI.8620	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	139	47	T	A	Aca/Gca	-9,22	0	0	probably_damaging	0,98	neutral	0,54	neutral	3,6	deleterious	-4,54	deleterious	-3,99	high_impact	4,78	neutral	0,95	damaging	0,11	neutral	1,55	13,56	0,18	0,45	disease	0,59	disease	0,69	disease	0,7	disease	0,66	3	neutral	0,97	neutral	0,28	deleterious	2	deleterious	0,77	low_impact	-2,31	medium_impact	0,26	high_impact	3,15	0,33	0,8	58,68	8,72	P	0,59	P	0,59	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14885	14885	A	C	MI.8621	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	139	47	T	P	Aca/Cca	-9,22	0	0	probably_damaging	1	neutral	0,14	neutral	3,53	deleterious	-6,83	deleterious	-4,8	high_impact	5,47	neutral	0,95	damaging	0,06	deleterious	3,1	22,5	0,04	0,35	disease	0,85	disease	0,87	disease	0,81	disease	0,67	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,21	high_impact	3,77	0,32	0,8	58,68	8,72	P	0,71	P	0,95	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14886	14886	C	T	MI.8622	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	140	47	T	M	aCa/aTa	6,84	1	0	probably_damaging	1	neutral	0,3	neutral	3,53	deleterious	-7,98	deleterious	-4,8	high_impact	5,47	neutral	0,94	damaging	0,1	deleterious	3,87	23,5	0,08	0,35	disease	0,88	disease	0,87	disease	0,73	disease	0,62	2	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,02	high_impact	3,77	0,55	0,8	58,68	8,72	P	0,77	P	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14886	14886	C	A	MI.8623	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	140	47	T	K	aCa/aAa	6,84	1	0	probably_damaging	1	neutral	0,2	neutral	3,54	deleterious	-6,78	deleterious	-4,8	high_impact	5,12	neutral	0,94	damaging	0,07	deleterious	4,26	23,9	0,06	0,35	disease	0,81	disease	0,91	disease	0,79	disease	0,7	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,1	high_impact	3,46	0,34	0,8	58,68	8,72	P	0,77	P	0,97	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14888	14888	G	C	MI.8624	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	142	48	G	R	Gga/Cga	-2,34	0	0	probably_damaging	1	neutral	0,35	neutral	1,7	deleterious	-12,38	deleterious	-6,49	high_impact	5,59	neutral	0,79	damaging	0,03	deleterious	3,81	23,4	0,02	0,35	disease	0,94	disease	0,9	disease	0,81	disease	0,64	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,53	medium_impact	0,08	high_impact	3,88	0,54	0,8	58,68	8,78	P	0,59	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14888	14888	G	T	MI.8625	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	142	48	G	W	Gga/Tga	-2,34	0	0	probably_damaging	1	neutral	0,18	neutral	1,7	deleterious	-14,22	deleterious	-6,49	high_impact	5,59	neutral	0,86	damaging	0,05	deleterious	4,28	24	0,03	0,35	disease	0,99	disease	0,9	disease	0,77	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,14	high_impact	3,88	0,11	0,8	58,68	8,78	N	0,53	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14889	14889	G	C	MI.8626	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	143	48	G	A	gGa/gCa	5,92	1	0	probably_damaging	1	neutral	0,51	neutral	1,73	deleterious	-10,66	deleterious	-4,86	high_impact	5,59	neutral	0,86	damaging	0,07	deleterious	2,82	21,4	0,04	0,35	disease	0,8	disease	0,67	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,23	high_impact	3,88	0,39	0,8	58,68	8,78	P	0,66	P	0,83	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14889	14889	G	T	MI.8627	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	143	48	G	V	gGa/gTa	5,92	1	0	probably_damaging	1	neutral	0,51	neutral	1,71	deleterious	-12,31	deleterious	-7,3	high_impact	5,59	neutral	0,81	damaging	0,06	deleterious	3,62	23,2	0,02	0,35	disease	0,93	disease	0,88	disease	0,73	disease	0,61	2	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,23	high_impact	3,88	0,17	0,8	58,68	8,78	P	0,64	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14889	14889	G	A	MI.8628	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	143	48	G	E	gGa/gAa	5,92	1	0	probably_damaging	1	neutral	0,27	neutral	1,71	deleterious	-11,98	deleterious	-6,49	high_impact	5,25	neutral	0,72	damaging	0,04	deleterious	3,76	23,3	0,02	0,35	disease	0,92	disease	0,87	disease	0,81	disease	0,64	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,01	high_impact	3,57	0,16	0,8	58,68	8,78	P	0,67	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14891	14891	C	A	MI.8629	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	145	49	L	M	Cta/Ata	-12,2	0	0	probably_damaging	1	neutral	0,22	neutral	4,4	neutral	-2,22	neutral	-1,53	high_impact	4,05	neutral	0,94	damaging	0,12	deleterious	3,39	23	0,18	0,45	disease	0,63	disease	0,62	neutral	0,49	neutral	0,48	0	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,75	low_impact	-3,53	medium_impact	-0,08	high_impact	2,48	0,62	0,8	57,89	8,64	N	0,39	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8932	8932	C	T	MI.863	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	406	136	P	S	Ccc/Tcc	-12,6	0	0	probably_damaging	1	neutral	0,41	neutral	4,35	neutral	-2,85	deleterious	-5,13	medium_impact	2,54	neutral	0,89	neutral	0,73	deleterious	2,86	21,7	0,38	0,65	disease	0,64	neutral	0,44	neutral	0,5	disease	0,61	2	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,74	low_impact	-3,6	medium_impact	0,2	medium_impact	1,08	0,5	0,9	18,14	17,08	N	0,46	N	0,13	polymorphism	1	0,08	rs878853013	Likely benign	not_provided	RCV000224223.1	MedGen	.	.	CPD	5,48	C8932T	Prostate Cancer/Neuromuscular disorder	+	-	Reported	3
chrM	14891	14891	C	G	MI.8630	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	145	49	L	V	Cta/Gta	-12,2	0	0	probably_damaging	0,96	neutral	0,5	neutral	4,55	neutral	-0,29	neutral	-2,15	medium_impact	2,82	neutral	0,96	damaging	0,12	neutral	1,51	13,38	0,2	0,45	neutral	0,18	disease	0,61	neutral	0,36	neutral	0,34	3	neutral	0,96	neutral	0,27	deleterious	1	deleterious	0,7	low_impact	-2,02	medium_impact	0,22	medium_impact	1,37	0,5	0,8	57,89	8,64	N	0,27	N	0,91	polymorphism	1	0,02	rs386419981	Likely pathogenic	Familial_cancer_of_breast	RCV000133407.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	14892	14892	T	C	MI.8631	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	146	49	L	P	cTa/cCa	-1,19	0	0	probably_damaging	1	neutral	0,2	neutral	4,34	deleterious	-4,34	deleterious	-5,52	high_impact	4,91	neutral	0,94	damaging	0,06	deleterious	3,81	23,4	0,03	0,35	disease	0,87	disease	0,82	disease	0,71	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,1	high_impact	3,26	0,27	0,8	57,89	8,64	P	0,65	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	COSM1155575	.	.	.	.	.	.	.	.
chrM	14892	14892	T	A	MI.8632	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	146	49	L	Q	cTa/cAa	-1,19	0	0	probably_damaging	1	neutral	0,3	neutral	4,34	deleterious	-4,05	deleterious	-4,77	high_impact	5,25	neutral	0,94	damaging	0,08	deleterious	4,01	23,6	0,04	0,35	disease	0,86	disease	0,81	disease	0,59	disease	0,62	2	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,02	high_impact	3,57	0,18	0,8	57,89	8,64	P	0,65	P	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14892	14892	T	G	MI.8633	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	146	49	L	R	cTa/cGa	-1,19	0	0	probably_damaging	1	neutral	0,34	neutral	4,35	deleterious	-3,88	deleterious	-4,78	high_impact	4,91	neutral	0,94	damaging	0,06	deleterious	3,92	23,5	0,03	0,35	disease	0,85	disease	0,89	disease	0,71	disease	0,64	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,07	high_impact	3,26	0,12	0,8	57,89	8,64	P	0,71	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14894	14894	T	C	MI.8634	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	148	50	F	L	Ttc/Ctc	-1,65	0	0	probably_damaging	0,98	neutral	1	neutral	4,69	neutral	0,44	deleterious	-3,94	medium_impact	2,08	neutral	0,95	neutral	0,49	deleterious	2,04	16,47	0,12	0,4	neutral	0,25	disease	0,71	neutral	0,49	neutral	0,16	7	neutral	0,98	deleterious	0,51	deleterious	1	deleterious	0,71	low_impact	-2,31	high_impact	1,85	medium_impact	0,7	0,4	0,8	55	7,81	N	0,22	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14894	14894	T	G	MI.8635	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	148	50	F	V	Ttc/Gtc	-1,65	0	0	probably_damaging	0,99	neutral	0,4	neutral	4,55	neutral	-0,76	deleterious	-4,94	high_impact	3,7	neutral	0,95	neutral	0,5	deleterious	3,59	23,2	0,1	0,4	disease	0,53	disease	0,87	disease	0,63	disease	0,68	4	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	0,13	high_impact	2,17	0,21	0,8	55	7,81	N	0,39	N	0,9	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14894	14894	T	A	MI.8636	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	148	50	F	I	Ttc/Atc	-1,65	0	0	probably_damaging	0,98	neutral	0,56	neutral	4,52	neutral	-0,83	deleterious	-4,13	high_impact	3,96	neutral	0,94	neutral	0,48	deleterious	2,63	20,4	0,12	0,4	disease	0,52	disease	0,84	disease	0,61	disease	0,66	3	deleterious	0,98	neutral	0,29	deleterious	2	deleterious	0,78	low_impact	-2,31	medium_impact	0,28	high_impact	2,4	0,28	0,8	55	7,81	N	0,33	N	0,8	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14895	14895	T	C	MI.8637	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	149	50	F	S	tTc/tCc	1,33	0,92	0	probably_damaging	1	neutral	0,36	neutral	4,42	neutral	-2,62	deleterious	-5,94	high_impact	4,14	neutral	0,94	neutral	0,44	deleterious	3,86	23,5	0,04	0,35	disease	0,75	disease	0,85	disease	0,66	disease	0,68	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,09	high_impact	2,57	0,17	0,8	55	7,81	N	0,46	N	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14895	14895	T	G	MI.8638	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	149	50	F	C	tTc/tGc	1,33	0,92	0	probably_damaging	1	neutral	0,1	neutral	4,4	deleterious	-3,93	deleterious	-5,85	high_impact	5,38	neutral	0,96	neutral	0,43	deleterious	3,95	23,6	0,05	0,35	disease	0,87	disease	0,86	disease	0,68	disease	0,64	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,3	high_impact	3,69	0,13	0,8	55	7,81	P	0,66	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14895	14895	T	A	MI.8639	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	149	50	F	Y	tTc/tAc	1,33	0,92	0	probably_damaging	0,98	neutral	0,86	neutral	4,41	neutral	-2,92	neutral	-2,25	high_impact	5,38	neutral	0,95	neutral	0,45	deleterious	2,53	19,66	0,13	0,4	disease	0,67	disease	0,78	disease	0,66	disease	0,67	3	neutral	0,97	neutral	0,44	deleterious	2	deleterious	0,79	low_impact	-2,31	medium_impact	0,65	high_impact	3,69	0,39	0,8	55	7,81	P	0,63	P	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8933	8933	C	T	MI.864	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	407	136	P	L	cCc/cTc	-0,33	0	0	probably_damaging	1	neutral	0,84	neutral	4,45	neutral	-1,44	deleterious	-5,66	neutral_impact	0,6	neutral	0,89	neutral	0,91	deleterious	2,18	17,4	0,4	0,65	disease	0,7	neutral	0,31	neutral	0,31	disease	0,62	2	deleterious	1	neutral	0,42	neutral	-2	deleterious	0,73	low_impact	-3,6	medium_impact	0,7	medium_impact	-0,58	0,77	0,9	18,14	17,08	N	0,31	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14896	14896	C	A	MI.8640	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	150	50	F	L	ttC/ttA	7,3	0,99	0	probably_damaging	0,98	neutral	1	neutral	4,69	neutral	0,44	deleterious	-3,94	medium_impact	2,08	neutral	0,95	neutral	0,49	deleterious	2,74	21	0,12	0,4	neutral	0,25	disease	0,71	neutral	0,49	neutral	0,16	7	neutral	0,98	deleterious	0,51	deleterious	1	deleterious	0,71	low_impact	-2,31	high_impact	1,85	medium_impact	0,7	0,4	0,8	55	7,81	N	0,48	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14896	14896	C	G	MI.8641	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	150	50	F	L	ttC/ttG	7,3	0,99	0	probably_damaging	0,98	neutral	1	neutral	4,69	neutral	0,44	deleterious	-3,94	medium_impact	2,08	neutral	0,95	neutral	0,49	deleterious	2,42	18,94	0,12	0,4	neutral	0,25	disease	0,71	neutral	0,49	neutral	0,16	7	neutral	0,98	deleterious	0,51	deleterious	1	deleterious	0,71	low_impact	-2,31	high_impact	1,85	medium_impact	0,7	0,4	0,8	55	7,81	N	0,47	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14897	14897	C	A	MI.8642	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	151	51	L	M	Cta/Ata	-2,57	0	0	probably_damaging	1	neutral	0,24	neutral	3,23	deleterious	-5,34	neutral	-1,58	high_impact	4,24	neutral	0,94	damaging	0,1	deleterious	3,4	23	0,17	0,45	neutral	0,43	disease	0,62	disease	0,61	disease	0,64	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,73	low_impact	-3,53	medium_impact	-0,05	high_impact	2,66	0,33	0,8	59,21	8,69	N	0,41	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14897	14897	C	G	MI.8643	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	151	51	L	V	Cta/Gta	-2,57	0	0	probably_damaging	0,96	neutral	0,45	neutral	3,27	deleterious	-4,66	neutral	-2,43	high_impact	4,04	neutral	0,96	damaging	0,11	neutral	1,52	13,4	0,17	0,45	disease	0,66	disease	0,64	disease	0,69	disease	0,66	3	neutral	0,96	neutral	0,25	deleterious	2	deleterious	0,79	low_impact	-2,02	medium_impact	0,18	high_impact	2,48	0,34	0,8	59,21	8,69	N	0,33	N	0,91	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14898	14898	T	A	MI.8644	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	152	51	L	Q	cTa/cAa	-0,5	0	0	probably_damaging	1	neutral	0,28	neutral	3,17	deleterious	-9,07	deleterious	-4,86	high_impact	5,56	neutral	0,94	damaging	0,07	deleterious	3,82	23,4	0,05	0,35	disease	0,93	disease	0,81	disease	0,69	disease	0,65	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0	high_impact	3,86	0,24	0,8	59,21	8,69	P	0,63	P	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14898	14898	T	C	MI.8645	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	152	51	L	P	cTa/cCa	-0,5	0	0	probably_damaging	1	neutral	0,17	neutral	3,17	deleterious	-8,92	deleterious	-5,69	high_impact	4,41	neutral	0,94	damaging	0,05	deleterious	3,74	23,3	0,03	0,35	disease	0,95	disease	0,8	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,15	high_impact	2,81	0,23	0,8	59,21	8,69	N	0,51	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14898	14898	T	G	MI.8646	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	152	51	L	R	cTa/cGa	-0,5	0	0	probably_damaging	1	neutral	0,29	neutral	3,17	deleterious	-8,98	deleterious	-4,87	high_impact	5,56	neutral	0,94	damaging	0,06	deleterious	3,92	23,5	0,03	0,35	disease	0,94	disease	0,89	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0,01	high_impact	3,86	0,15	0,8	59,21	8,69	P	0,71	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14900	14900	G	T	MI.8647	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	154	52	A	S	Gcc/Tcc	-0,04	0,94	0	probably_damaging	1	neutral	0,45	neutral	4,38	neutral	-0,62	neutral	-2,16	medium_impact	2,2	neutral	0,97	neutral	0,52	deleterious	3,17	22,7	0,19	0,45	disease	0,76	disease	0,76	neutral	0,45	neutral	0,23	5	deleterious	1	neutral	0,23	deleterious	1	deleterious	0,85	low_impact	-3,53	medium_impact	0,18	medium_impact	0,8	0,34	0,8	57,37	8,4	N	0,35	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14900	14900	G	C	MI.8648	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	154	52	A	P	Gcc/Ccc	-0,04	0,94	0	probably_damaging	1	neutral	0,19	neutral	4,31	deleterious	-3,99	deleterious	-3,92	high_impact	5,39	neutral	0,94	damaging	0,26	deleterious	3,56	23,1	0,04	0,35	disease	0,9	disease	0,86	disease	0,76	disease	0,63	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,12	high_impact	3,7	0,51	0,8	57,37	8,4	P	0,71	P	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14900	14900	G	A	MI.8649	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	154	52	A	T	Gcc/Acc	-0,04	0,94	0	probably_damaging	1	neutral	0,48	neutral	4,42	neutral	-2,16	deleterious	-3,03	medium_impact	2,84	neutral	0,91	neutral	0,47	deleterious	3,82	23,4	0,12	0,4	disease	0,81	disease	0,79	neutral	0,49	neutral	0,46	1	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,85	low_impact	-3,53	medium_impact	0,2	medium_impact	1,39	0,52	0,8	57,37	8,4	N	0,36	N	0,79	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8933	8933	C	A	MI.865	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	407	136	P	H	cCc/cAc	-0,33	0	0	probably_damaging	1	neutral	0,54	neutral	4,31	deleterious	-4,57	deleterious	-5,96	high_impact	3,58	neutral	0,82	neutral	0,44	deleterious	4,1	23,7	0,24	0,65	disease	0,83	disease	0,6	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-3,6	medium_impact	0,33	medium_impact	1,97	0,72	0,9	18,14	17,08	N	0,27	N	0,95	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14901	14901	C	A	MI.8650	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	155	52	A	D	gCc/gAc	5,92	1	0	probably_damaging	1	neutral	0,22	neutral	4,31	deleterious	-4,11	deleterious	-4,64	high_impact	5,39	neutral	0,92	neutral	0,37	deleterious	4,37	24,1	0,04	0,35	disease	0,92	disease	0,91	disease	0,74	disease	0,62	2	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,08	high_impact	3,7	0,24	0,8	57,37	8,4	P	0,79	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14901	14901	C	T	MI.8651	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	155	52	A	V	gCc/gTc	5,92	1	0	probably_damaging	1	neutral	0,54	neutral	4,45	neutral	-1,4	deleterious	-3,19	high_impact	3,85	neutral	0,95	neutral	0,5	deleterious	3,96	23,6	0,09	0,35	disease	0,86	disease	0,82	disease	0,66	disease	0,63	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,26	high_impact	2,3	0,61	0,8	57,37	8,4	P	0,6	P	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14901	14901	C	G	MI.8652	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	155	52	A	G	gCc/gGc	5,92	1	0	probably_damaging	0,99	neutral	0,43	neutral	4,35	deleterious	-3,4	deleterious	-3,12	high_impact	4,58	neutral	0,93	neutral	0,5	deleterious	2,15	17,19	0,16	0,45	disease	0,82	disease	0,77	disease	0,64	disease	0,65	3	deleterious	0,99	neutral	0,22	deleterious	2	deleterious	0,83	low_impact	-2,59	medium_impact	0,16	high_impact	2,97	0,58	0,8	57,37	8,4	P	0,66	P	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14903	14903	A	G	MI.8653	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	157	53	M	V	Atg/Gtg	-9,22	0	0	probably_damaging	0,91	neutral	0,5	neutral	4,43	neutral	-1,65	deleterious	-3,11	high_impact	3,6	neutral	0,87	damaging	0,1	deleterious	0,85	9,76	0,18	0,45	neutral	0,45	disease	0,76	disease	0,75	disease	0,69	4	neutral	0,9	neutral	0,3	deleterious	2	deleterious	0,74	low_impact	-1,67	medium_impact	0,22	high_impact	2,08	0,22	0,8	59,21	8,84	N	0,31	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14903	14903	A	C	MI.8654	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	157	53	M	L	Atg/Ctg	-9,22	0	0	possibly_damaging	0,86	neutral	0,68	neutral	4,53	neutral	-0,52	neutral	-2,35	medium_impact	3,23	neutral	0,87	damaging	0,08	neutral	1,44	13,01	0,17	0,45	neutral	0,41	disease	0,76	disease	0,66	disease	0,66	3	neutral	0,84	neutral	0,41	NA	0	deleterious	0,68	low_impact	-1,47	medium_impact	0,4	medium_impact	1,74	0,29	0,8	59,21	8,84	N	0,21	N	0,92	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14903	14903	A	T	MI.8655	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	157	53	M	L	Atg/Ttg	-9,22	0	0	possibly_damaging	0,86	neutral	0,68	neutral	4,53	neutral	-0,52	neutral	-2,35	medium_impact	3,23	neutral	0,87	damaging	0,08	neutral	1,5	13,32	0,17	0,45	neutral	0,41	disease	0,76	disease	0,66	disease	0,66	3	neutral	0,84	neutral	0,41	NA	0	deleterious	0,68	low_impact	-1,47	medium_impact	0,4	medium_impact	1,74	0,29	0,8	59,21	8,84	N	0,21	N	0,92	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14904	14904	T	A	MI.8656	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	158	53	M	K	aTg/aAg	4,54	0,99	0	probably_damaging	1	neutral	0,29	neutral	4,33	deleterious	-3,97	deleterious	-4,73	high_impact	5,44	neutral	0,85	damaging	0,08	deleterious	2,4	18,85	0,04	0,35	disease	0,73	disease	0,85	disease	0,8	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,01	high_impact	3,75	0,14	0,8	59,21	8,84	P	0,77	P	0,99	disease_causing	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14904	14904	T	C	MI.8657	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	158	53	M	T	aTg/aCg	4,54	0,99	0	probably_damaging	1	neutral	0,4	neutral	4,38	neutral	-2,65	deleterious	-4,58	high_impact	3,85	neutral	0,85	damaging	0,11	deleterious	2,62	20,3	0,09	0,35	disease	0,58	disease	0,79	disease	0,72	neutral	0,42	2	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,13	high_impact	2,3	0,11	0,8	59,21	8,84	N	0,49	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14905	14905	G	T	MI.8658	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	159	53	M	I	atG/atT	2,71	0,99	0,1	probably_damaging	0,94	neutral	0,4	neutral	4,42	neutral	-1,88	deleterious	-3,13	medium_impact	3,25	neutral	0,85	damaging	0,09	neutral	1,72	14,49	0,13	0,4	neutral	0,48	disease	0,79	disease	0,71	disease	0,67	3	neutral	0,94	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-1,85	medium_impact	0,13	medium_impact	1,76	0,29	0,8	59,21	8,84	N	0,36	N	0,95	disease_causing	1	0,02	rs193302983	Likely pathogenic	Familial_cancer_of_breast	RCV000133450.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	14905	14905	G	C	MI.8659	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	159	53	M	I	atG/atC	2,71	0,99	0,1	probably_damaging	0,94	neutral	0,4	neutral	4,42	neutral	-1,88	deleterious	-3,13	medium_impact	3,25	neutral	0,85	damaging	0,09	neutral	1,61	13,88	0,13	0,4	neutral	0,48	disease	0,79	disease	0,71	disease	0,67	3	neutral	0,94	neutral	0,23	deleterious	1	deleterious	0,77	low_impact	-1,85	medium_impact	0,13	medium_impact	1,76	0,29	0,8	59,21	8,84	N	0,35	N	0,95	disease_causing	1	0,02	rs193302983	Likely pathogenic	Familial_cancer_of_breast	RCV000133450.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	8933	8933	C	G	MI.866	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	407	136	P	R	cCc/cGc	-0,33	0	0	probably_damaging	1	neutral	0,35	neutral	4,32	deleterious	-3,95	deleterious	-5,95	medium_impact	3,23	neutral	0,82	neutral	0,42	deleterious	3,59	23,2	0,2	0,65	disease	0,67	disease	0,69	disease	0,68	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	0,14	medium_impact	1,67	0,68	0,9	18,14	17,08	N	0,29	N	0,96	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14906	14906	C	G	MI.8660	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	160	54	H	D	Cac/Gac	-0,04	0,76	0	probably_damaging	0,99	neutral	0,21	neutral	4,5	neutral	-1,84	deleterious	-7,37	high_impact	5,5	neutral	0,72	neutral	0,36	deleterious	2,17	17,31	0,04	0,35	disease	0,75	disease	0,85	disease	0,84	disease	0,73	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,83	low_impact	-2,59	medium_impact	-0,09	high_impact	3,8	0,27	0,8	58,42	8,9	P	0,66	P	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14906	14906	C	T	MI.8661	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	160	54	H	Y	Cac/Tac	-0,04	0,76	0	probably_damaging	0,98	neutral	1	neutral	4,73	deleterious	-3,73	deleterious	-4,91	medium_impact	3,4	neutral	0,84	neutral	0,39	deleterious	1,84	15,24	0,09	0,35	neutral	0,45	disease	0,85	disease	0,7	disease	0,69	4	deleterious	0,98	deleterious	0,51	deleterious	1	deleterious	0,8	low_impact	-2,31	high_impact	1,85	medium_impact	1,89	0,27	0,8	58,42	8,9	N	0,24	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14906	14906	C	A	MI.8662	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	160	54	H	N	Cac/Aac	-0,04	0,76	0	probably_damaging	0,99	neutral	0,3	neutral	4,54	neutral	-1,86	deleterious	-5,73	high_impact	3,82	neutral	0,83	neutral	0,43	deleterious	2,02	16,31	0,18	0,45	disease	0,72	disease	0,84	disease	0,79	disease	0,7	4	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	0,02	high_impact	2,28	0,26	0,8	58,42	8,9	N	0,41	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14907	14907	A	C	MI.8663	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	161	54	H	P	cAc/cCc	5,46	1	0	probably_damaging	1	neutral	0,2	neutral	4,48	deleterious	-3,24	deleterious	-8,19	high_impact	4,95	neutral	0,84	damaging	0,28	neutral	1,56	13,64	0,02	0,35	disease	0,84	disease	0,86	disease	0,86	disease	0,7	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,1	high_impact	3,3	0,16	0,8	58,42	8,9	P	0,73	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14907	14907	A	T	MI.8664	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	161	54	H	L	cAc/cTc	5,46	1	0	probably_damaging	0,98	neutral	0,68	neutral	4,57	neutral	-2,61	deleterious	-9,01	high_impact	4,53	neutral	0,84	neutral	0,38	deleterious	2,01	16,25	0,03	0,35	disease	0,62	disease	0,9	disease	0,78	disease	0,72	4	deleterious	0,98	neutral	0,35	deleterious	2	deleterious	0,83	low_impact	-2,31	medium_impact	0,4	high_impact	2,92	0,15	0,8	58,42	8,9	P	0,63	P	0,92	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14907	14907	A	G	MI.8665	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	161	54	H	R	cAc/cGc	5,46	1	0	probably_damaging	0,98	neutral	0,32	neutral	4,52	neutral	-0,1	deleterious	-6,55	high_impact	4,46	neutral	0,84	neutral	0,34	neutral	1,15	11,48	0,07	0,35	disease	0,5	disease	0,88	disease	0,75	disease	0,7	4	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-2,31	medium_impact	0,05	high_impact	2,86	0,33	0,8	58,42	8,9	P	0,58	P	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14908	14908	C	A	MI.8666	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	162	54	H	Q	caC/caA	6,84	1	0	probably_damaging	0,99	neutral	0,27	neutral	4,51	neutral	-1,56	deleterious	-6,55	high_impact	4,4	neutral	0,84	neutral	0,36	deleterious	1,96	15,99	0,1	0,4	disease	0,69	disease	0,81	disease	0,73	disease	0,69	4	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	-0,01	high_impact	2,8	0,38	0,8	58,42	8,9	P	0,61	P	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14908	14908	C	G	MI.8667	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	162	54	H	Q	caC/caG	6,84	1	0	probably_damaging	0,99	neutral	0,27	neutral	4,51	neutral	-1,56	deleterious	-6,55	high_impact	4,4	neutral	0,84	neutral	0,36	neutral	1,7	14,41	0,1	0,4	disease	0,69	disease	0,81	disease	0,73	disease	0,69	4	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	-0,01	high_impact	2,8	0,38	0,8	58,42	8,9	P	0,61	P	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14909	14909	T	G	MI.8668	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	163	55	Y	D	Tac/Gac	-0,96	0,02	0	probably_damaging	1	neutral	0,21	neutral	2,74	deleterious	-9,74	deleterious	-8,18	high_impact	5,22	neutral	0,83	damaging	0,07	deleterious	3,71	23,3	0,03	0,35	disease	0,96	disease	0,84	disease	0,84	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,09	high_impact	3,55	0,15	0,8	56,84	8,8	P	0,58	P	1	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14909	14909	T	A	MI.8669	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	163	55	Y	N	Tac/Aac	-0,96	0,02	0	probably_damaging	1	neutral	0,29	neutral	2,74	deleterious	-8,75	deleterious	-7,37	high_impact	5,57	neutral	0,85	damaging	0,09	deleterious	3,95	23,6	0,06	0,35	disease	0,92	disease	0,81	disease	0,78	disease	0,67	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,01	high_impact	3,86	0,13	0,8	56,84	8,8	P	0,62	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8935	8935	C	G	MI.867	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	409	137	L	V	Ctt/Gtt	-20	0	0	probably_damaging	0,99	deleterious	0	neutral	3,7	deleterious	-3,32	deleterious	-2,7	high_impact	4,05	damaging	0,38	damaging	0,1	deleterious	3,5	23,1	0,38	0,65	disease	0,59	disease	0,52	disease	0,76	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,78	low_impact	-2,65	low_impact	-1,4	high_impact	2,37	0,75	0,9	49,56	8,85	N	0,42	N	0,87	polymorphism	0,97	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14909	14909	T	C	MI.8670	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	163	55	Y	H	Tac/Cac	-0,96	0,02	0	probably_damaging	1	neutral	0,59	neutral	2,77	deleterious	-6,67	deleterious	-4,1	high_impact	4,88	neutral	0,89	damaging	0,08	deleterious	3,34	22,9	0,11	0,4	disease	0,84	disease	0,75	disease	0,83	disease	0,7	4	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,31	high_impact	3,24	0,14	0,8	56,84	8,8	P	0,68	P	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14910	14910	A	T	MI.8671	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	164	55	Y	F	tAc/tTc	3,63	1	0	probably_damaging	0,99	neutral	0,71	neutral	2,9	deleterious	-4,62	deleterious	-3,24	medium_impact	3,29	neutral	0,91	damaging	0,08	neutral	1,61	13,9	0,17	0,45	disease	0,51	disease	0,75	neutral	0,5	neutral	0,37	3	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,8	low_impact	-2,59	medium_impact	0,43	medium_impact	1,79	0,42	0,8	56,84	8,8	N	0,41	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14910	14910	A	C	MI.8672	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	164	55	Y	S	tAc/tCc	3,63	1	0	probably_damaging	1	neutral	0,41	neutral	2,75	deleterious	-8,52	deleterious	-7,36	high_impact	5,22	neutral	0,88	damaging	0,09	deleterious	3,41	23	0,06	0,35	disease	0,91	disease	0,81	disease	0,77	disease	0,67	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,14	high_impact	3,55	0,12	0,8	56,84	8,8	P	0,65	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14910	14910	A	G	MI.8673	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	164	55	Y	C	tAc/tGc	3,63	1	0	probably_damaging	1	neutral	0,18	neutral	2,74	deleterious	-10,11	deleterious	-7,36	high_impact	5,22	neutral	0,85	damaging	0,05	deleterious	3,38	23	0,05	0,35	disease	0,96	disease	0,83	disease	0,79	disease	0,67	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,14	high_impact	3,55	0,17	0,8	56,84	8,8	P	0,57	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14912	14912	T	A	MI.8674	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	166	56	S	T	Tca/Aca	-2,34	0	0	benign	0	neutral	0,48	neutral	4,81	neutral	2,35	neutral	2,34	neutral_impact	-2,13	neutral	0,96	neutral	0,9	neutral	-0,68	0,08	0,3	0,45	neutral	0,16	neutral	0,05	neutral	0,16	neutral	0,21	6	neutral	0,52	deleterious	0,74	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,2	low_impact	-3,13	0,57	0,8	20,79	48,85	N	0,47	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14912	14912	T	C	MI.8675	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	166	56	S	P	Tca/Cca	-2,34	0	0	benign	0,15	neutral	0,19	neutral	4,59	neutral	-1,77	neutral	-1,99	medium_impact	2,58	neutral	0,84	neutral	0,44	deleterious	2,29	18,11	0,05	0,35	disease	0,7	disease	0,82	disease	0,55	disease	0,72	4	neutral	0,78	deleterious	0,52	neutral	-3	deleterious	0,44	medium_impact	-0,03	medium_impact	-0,12	medium_impact	1,15	0,24	0,8	20,79	48,85	N	0,29	N	0,75	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14912	14912	T	G	MI.8676	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	166	56	S	A	Tca/Gca	-2,34	0	0	benign	0	neutral	0,49	neutral	4,67	neutral	0,77	neutral	-1	low_impact	0,98	neutral	0,83	neutral	0,81	neutral	1,74	14,65	0,32	0,5	neutral	0,36	neutral	0,3	neutral	0,28	neutral	0,43	1	neutral	0,51	deleterious	0,75	neutral	-6	neutral	0,16	high_impact	2,07	medium_impact	0,21	medium_impact	-0,3	0,4	0,8	20,79	48,85	N	0,38	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14913	14913	C	T	MI.8677	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	167	56	S	L	tCa/tTa	3,63	0,99	0	benign	0,05	neutral	0,6	neutral	4,61	neutral	-0,72	neutral	-2,03	medium_impact	1,97	neutral	0,77	neutral	0,58	deleterious	2,91	21,9	0,06	0,35	neutral	0,42	disease	0,66	disease	0,55	disease	0,66	3	neutral	0,34	deleterious	0,78	neutral	-3	neutral	0,24	medium_impact	0,46	medium_impact	0,32	medium_impact	0,6	0,38	0,8	20,79	48,85	N	0,41	N	0,72	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14913	14913	C	G	MI.8678	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	167	56	S	W	tCa/tGa	3,63	0,99	0	possibly_damaging	0,67	neutral	0,15	neutral	4,57	deleterious	-4	deleterious	-2,92	medium_impact	3,12	neutral	0,85	neutral	0,48	deleterious	4,11	23,7	0,06	0,35	disease	0,86	disease	0,79	disease	0,66	disease	0,71	4	neutral	0,87	neutral	0,24	NA	0	deleterious	0,73	low_impact	-1,02	medium_impact	-0,19	medium_impact	1,64	0,12	0,8	20,79	48,85	N	0,45	N	0,87	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14915	14915	C	T	MI.8679	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	169	57	P	S	Cca/Tca	-3,94	0	0	benign	0,02	neutral	0,56	neutral	4,16	deleterious	-4,37	neutral	0,84	neutral_impact	0,24	neutral	0,95	neutral	0,98	deleterious	0,86	9,81	0,19	0,45	neutral	0,17	neutral	0,13	neutral	0,26	neutral	0,28	4	neutral	0,41	deleterious	0,77	neutral	-6	neutral	0,1	medium_impact	0,85	medium_impact	0,28	medium_impact	-0,98	0,1	0,8	20	28,35	N	0,31	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8935	8935	C	A	MI.868	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	409	137	L	I	Ctt/Att	-20	0	0	probably_damaging	0,99	deleterious	0,04	neutral	3,71	deleterious	-3,21	neutral	-1,8	medium_impact	3,19	damaging	0,49	damaging	0,11	deleterious	4,2	23,9	0,31	0,65	disease	0,62	neutral	0,48	disease	0,61	disease	0,6	2	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,77	low_impact	-2,65	medium_impact	-0,49	medium_impact	1,64	0,72	0,9	49,56	8,85	N	0,32	N	0,87	polymorphism	0,98	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14915	14915	C	G	MI.8680	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	169	57	P	A	Cca/Gca	-3,94	0	0	benign	0,14	neutral	0,53	neutral	4,19	deleterious	-4,15	neutral	0,99	neutral_impact	-0,39	neutral	0,97	neutral	0,94	deleterious	0,63	8,35	0,15	0,45	neutral	0,27	neutral	0,09	neutral	0,22	neutral	0,24	5	neutral	0,37	deleterious	0,7	neutral	-6	neutral	0,23	medium_impact	0	medium_impact	0,25	low_impact	-1,55	0,58	0,8	20	28,35	N	0,34	N	0,08	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14915	14915	C	A	MI.8681	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	169	57	P	T	Cca/Aca	-3,94	0	0	benign	0,31	neutral	0,51	neutral	4,06	deleterious	-4,89	neutral	-0,36	medium_impact	2,88	neutral	0,92	neutral	0,6	deleterious	3,38	22,9	0,15	0,45	disease	0,55	neutral	0,34	neutral	0,32	disease	0,59	2	neutral	0,4	deleterious	0,6	neutral	-3	neutral	0,38	medium_impact	-0,41	medium_impact	0,23	medium_impact	1,42	0,47	0,8	20	28,35	N	0,36	N	0,4	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14916	14916	C	A	MI.8682	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	170	57	P	Q	cCa/cAa	-0,04	0,02	0	possibly_damaging	0,7	neutral	0,27	neutral	4,03	deleterious	-6,8	neutral	-1,06	high_impact	4,37	neutral	0,93	neutral	0,53	deleterious	3,91	23,5	0,09	0,4	disease	0,73	neutral	0,48	disease	0,65	disease	0,68	4	neutral	0,79	neutral	0,29	deleterious	1	deleterious	0,63	low_impact	-1,07	medium_impact	-0,01	high_impact	2,77	0,3	0,8	20	28,35	P	0,54	P	0,57	polymorphism	1	0,13	rs56787243	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14916	14916	C	G	MI.8683	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	170	57	P	R	cCa/cGa	-0,04	0,02	0	possibly_damaging	0,71	neutral	0,33	neutral	4,03	deleterious	-6,86	neutral	-1,52	high_impact	4,37	neutral	0,93	neutral	0,48	deleterious	3,35	22,9	0,08	0,35	disease	0,71	disease	0,72	disease	0,76	disease	0,72	4	neutral	0,76	neutral	0,31	deleterious	1	deleterious	0,65	low_impact	-1,09	medium_impact	0,06	high_impact	2,77	0,26	0,8	20	28,35	N	0,5	N	0,75	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14916	14916	C	T	MI.8684	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	170	57	P	L	cCa/cTa	-0,04	0,02	0	possibly_damaging	0,52	neutral	0,63	neutral	4,04	deleterious	-6,21	neutral	-1,98	high_impact	3,82	neutral	0,93	neutral	0,53	deleterious	4,04	23,7	0,12	0,4	disease	0,74	disease	0,58	disease	0,59	disease	0,67	3	neutral	0,45	deleterious	0,56	deleterious	1	deleterious	0,55	medium_impact	-0,76	medium_impact	0,35	high_impact	2,28	0,68	0,85	20	28,35	N	0,32	N	0,8	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14918	14918	G	T	MI.8685	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	172	58	D	Y	Gac/Tac	-3,94	0	0	probably_damaging	1	neutral	1	neutral	4,46	deleterious	-3,68	deleterious	-6,68	high_impact	4,64	neutral	0,91	neutral	0,43	deleterious	3,78	23,4	0,05	0,35	disease	0,83	disease	0,9	disease	0,66	disease	0,64	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,85	low_impact	-3,53	high_impact	1,85	high_impact	3,02	0,08	0,8	50,53	7,84	N	0,43	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14918	14918	G	A	MI.8686	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	172	58	D	N	Gac/Aac	-3,94	0	0	probably_damaging	1	neutral	0,32	neutral	4,55	neutral	-0,88	deleterious	-3,4	low_impact	1,66	neutral	0,65	neutral	0,52	deleterious	3,76	23,3	0,49	0,55	neutral	0,25	disease	0,72	neutral	0,29	neutral	0,19	6	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,71	low_impact	-3,53	medium_impact	0,05	medium_impact	0,31	0,49	0,8	50,53	7,84	N	0,38	N	0,99	polymorphism	1	0,03	.	.	.	.	.	.	COSM1138284	.	.	.	.	.	.	.	.
chrM	14918	14918	G	C	MI.8687	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	172	58	D	H	Gac/Cac	-3,94	0	0	probably_damaging	1	neutral	0,55	neutral	4,5	neutral	-2,07	deleterious	-4,89	medium_impact	2,64	neutral	0,9	neutral	0,33	deleterious	3,54	23,1	0,11	0,4	neutral	0,33	disease	0,8	neutral	0,39	neutral	0,41	2	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,76	low_impact	-3,53	medium_impact	0,27	medium_impact	1,2	0,33	0,8	50,53	7,84	N	0,26	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14919	14919	A	T	MI.8688	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	173	58	D	V	gAc/gTc	4,31	1	0	probably_damaging	1	neutral	0,52	neutral	4,49	deleterious	-4,01	deleterious	-6,87	high_impact	5,19	neutral	0,91	neutral	0,48	deleterious	3,55	23,1	0,04	0,35	disease	0,75	disease	0,89	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,24	high_impact	3,52	0,08	0,8	50,53	7,84	P	0,67	P	1	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14919	14919	A	C	MI.8689	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	173	58	D	A	gAc/gCc	4,31	1	0	probably_damaging	1	neutral	0,56	neutral	4,54	neutral	-1,73	deleterious	-6,03	high_impact	4,38	neutral	0,91	neutral	0,46	deleterious	3,18	22,7	0,07	0,35	disease	0,55	disease	0,73	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,28	high_impact	2,78	0,18	0,8	50,53	7,84	N	0,51	P	0,94	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8935	8935	C	T	MI.869	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	409	137	L	F	Ctt/Ttt	-20	0	0	probably_damaging	1	deleterious	0,04	neutral	3,78	neutral	-2,42	deleterious	-3,6	high_impact	4,25	damaging	0,44	damaging	0,1	deleterious	4	23,6	0,38	0,65	disease	0,74	disease	0,55	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,81	low_impact	-3,6	medium_impact	-0,49	high_impact	2,54	0,66	0,9	49,56	8,85	N	0,39	N	0,97	polymorphism	0,86	0,2	rs28377547	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14919	14919	A	G	MI.8690	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	173	58	D	G	gAc/gGc	4,31	1	0	probably_damaging	1	neutral	0,34	neutral	4,5	neutral	-1,14	deleterious	-5,22	high_impact	3,9	neutral	0,9	neutral	0,47	deleterious	3,69	23,3	0,08	0,35	disease	0,63	disease	0,86	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,07	high_impact	2,35	0,2	0,8	50,53	7,84	P	0,61	P	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14920	14920	C	G	MI.8691	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	174	58	D	E	gaC/gaG	6,84	1	0	probably_damaging	0,98	neutral	0,31	neutral	4,61	neutral	-1,09	deleterious	-2,95	medium_impact	2,87	neutral	0,89	neutral	0,43	deleterious	2	16,24	0,25	0,45	neutral	0,32	disease	0,71	neutral	0,44	neutral	0,35	3	neutral	0,98	neutral	0,17	deleterious	1	deleterious	0,72	low_impact	-2,31	medium_impact	0,03	medium_impact	1,41	0,27	0,8	50,53	7,84	P	0,61	P	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14920	14920	C	A	MI.8692	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	174	58	D	E	gaC/gaA	6,84	1	0	probably_damaging	0,98	neutral	0,31	neutral	4,61	neutral	-1,09	deleterious	-2,95	medium_impact	2,87	neutral	0,89	neutral	0,43	deleterious	2,35	18,47	0,25	0,45	neutral	0,32	disease	0,71	neutral	0,44	neutral	0,35	3	neutral	0,98	neutral	0,17	deleterious	1	deleterious	0,72	low_impact	-2,31	medium_impact	0,03	medium_impact	1,41	0,27	0,8	50,53	7,84	P	0,61	P	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14921	14921	G	A	MI.8693	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	175	59	A	T	Gcc/Acc	-0,96	0	0	probably_damaging	1	neutral	0,41	neutral	4,66	neutral	1,42	neutral	1,39	neutral_impact	-2,25	neutral	0,95	neutral	0,87	neutral	1,13	11,38	0,24	0,45	neutral	0,15	neutral	0,08	neutral	0,11	neutral	0,3	4	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,62	low_impact	-3,53	medium_impact	0,14	low_impact	-3,24	0,65	0,8	16,32	12,69	N	0,45	N	0	polymorphism	1	0	.	.	.	.	.	.	COSM1138286	.	.	.	.	.	.	.	.
chrM	14921	14921	G	T	MI.8694	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	175	59	A	S	Gcc/Tcc	-0,96	0	0	probably_damaging	0,99	neutral	0,44	neutral	4,57	neutral	-0,3	neutral	-0,32	neutral_impact	0,28	neutral	0,94	neutral	0,64	deleterious	1,98	16,08	0,29	0,45	neutral	0,27	neutral	0,46	neutral	0,41	neutral	0,45	1	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,71	low_impact	-2,59	medium_impact	0,17	medium_impact	-0,94	0,42	0,8	16,32	12,69	N	0,35	N	0,55	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14921	14921	G	C	MI.8695	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	175	59	A	P	Gcc/Ccc	-0,96	0	0	probably_damaging	1	neutral	0,21	neutral	4,54	neutral	-1,99	neutral	-1,48	low_impact	1,73	neutral	0,94	neutral	0,4	deleterious	3,54	23,1	0,08	0,35	disease	0,6	disease	0,8	disease	0,57	disease	0,71	4	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,09	medium_impact	0,38	0,51	0,8	16,32	12,69	N	0,36	N	0,75	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14922	14922	C	T	MI.8696	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	176	59	A	V	gCc/gTc	4,54	0,84	0	probably_damaging	1	neutral	0,5	neutral	4,67	neutral	1,03	neutral	1,6	neutral_impact	-0,8	neutral	0,95	neutral	0,75	deleterious	2,96	22,1	0,19	0,45	neutral	0,15	neutral	0,45	neutral	0,13	neutral	0,4	2	deleterious	0,99	neutral	0,25	neutral	-2	deleterious	0,64	low_impact	-3,53	medium_impact	0,22	low_impact	-1,92	0,73	0,85	16,32	12,69	N	0,37	N	0,43	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14922	14922	C	G	MI.8697	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	176	59	A	G	gCc/gGc	4,54	0,84	0	probably_damaging	0,99	neutral	0,33	neutral	4,55	neutral	-1,44	neutral	-2,2	low_impact	1,18	neutral	0,93	neutral	0,61	deleterious	2,31	18,25	0,26	0,45	disease	0,52	disease	0,55	neutral	0,39	neutral	0,45	1	deleterious	0,99	neutral	0,17	neutral	-2	deleterious	0,75	low_impact	-2,59	medium_impact	0,06	medium_impact	-0,12	0,59	0,8	16,32	12,69	N	0,43	N	0,64	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14922	14922	C	A	MI.8698	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	176	59	A	D	gCc/gAc	4,54	0,84	0	probably_damaging	1	neutral	0,27	neutral	4,52	neutral	-1,2	neutral	-1,57	low_impact	1,27	neutral	0,93	neutral	0,49	deleterious	4,26	23,9	0,08	0,35	disease	0,63	disease	0,8	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,14	neutral	-2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,01	medium_impact	-0,04	0,28	0,8	16,32	12,69	N	0,42	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14924	14924	T	A	MI.8699	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	178	60	S	T	Tca/Aca	-5,09	0	0	benign	0	neutral	0,41	neutral	4,58	neutral	-2,16	neutral	-0,96	neutral_impact	0,5	neutral	0,98	neutral	0,97	neutral	-0,31	0,62	0,23	0,45	neutral	0,24	neutral	0,19	neutral	0,19	neutral	0,35	3	neutral	0,59	deleterious	0,71	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,14	medium_impact	-0,74	0,53	0,8	20,53	23,72	N	0,56	P	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8566	8566	A	G	MI.87	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	40	14	I	V	Atc/Gtc	-0,8	0	0,01	benign	0,01	neutral	0,4	neutral	4,69	neutral	0,08	neutral	-0,53	neutral_impact	-0,06	neutral	0,99	neutral	0,95	deleterious	0,21	4,78	0,68	0,75	neutral	0,41	neutral	0,22	disease	0,52	neutral	0,4	2	neutral	0,59	deleterious	0,7	neutral	-6	neutral	0,1	medium_impact	1,14	medium_impact	0,19	low_impact	-1,15	0,56	0,9	13,72	12,42	N	0,34	N	0,05	polymorphism	1	0,01	rs3020563	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8936	8936	T	G	MI.870	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	410	137	L	R	cTt/cGt	-0,1	0	0	probably_damaging	1	deleterious	0	neutral	3,61	deleterious	-5,9	deleterious	-5,41	high_impact	4,61	damaging	0,34	damaging	0,09	deleterious	4,22	23,9	0,12	0,65	disease	0,88	disease	0,81	disease	0,83	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,85	0,46	0,9	49,56	8,85	P	0,62	P	0,99	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14924	14924	T	C	MI.8700	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	178	60	S	P	Tca/Cca	-5,09	0	0	benign	0,33	neutral	0,2	neutral	4,48	deleterious	-3,77	deleterious	-2,94	high_impact	3,9	neutral	0,93	neutral	0,43	deleterious	2,06	16,61	0,08	0,35	disease	0,56	disease	0,83	disease	0,66	disease	0,7	4	neutral	0,76	neutral	0,44	neutral	-2	deleterious	0,49	medium_impact	-0,44	medium_impact	-0,1	high_impact	2,35	0,33	0,8	20,53	23,72	N	0,4	N	0,73	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14924	14924	T	G	MI.8701	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	178	60	S	A	Tca/Gca	-5,09	0	0	benign	0,05	neutral	0,52	neutral	4,6	neutral	-2,07	neutral	-1,41	low_impact	1,12	neutral	0,98	neutral	0,97	neutral	-0,18	1,2	0,23	0,45	neutral	0,3	neutral	0,19	neutral	0,39	neutral	0,35	3	neutral	0,43	deleterious	0,74	neutral	-6	neutral	0,11	medium_impact	0,46	medium_impact	0,24	medium_impact	-0,18	0,35	0,8	20,53	23,72	N	0,42	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14925	14925	C	T	MI.8702	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	179	60	S	L	tCa/tTa	-4,86	0	0	benign	0,27	neutral	0,66	neutral	4,5	deleterious	-3,29	deleterious	-3,19	low_impact	1,75	neutral	0,96	neutral	0,81	neutral	1,32	12,38	0,13	0,4	neutral	0,32	disease	0,71	neutral	0,43	neutral	0,17	7	neutral	0,24	deleterious	0,7	neutral	-6	neutral	0,37	medium_impact	-0,33	medium_impact	0,38	medium_impact	0,4	0,38	0,8	20,53	23,72	N	0,24	N	0,11	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14925	14925	C	G	MI.8703	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	179	60	S	W	tCa/tGa	-4,86	0	0	possibly_damaging	0,89	neutral	0,18	neutral	4,46	deleterious	-6,4	deleterious	-4,23	high_impact	3,76	neutral	0,95	neutral	0,47	deleterious	3,06	22,4	0,07	0,35	disease	0,85	disease	0,83	disease	0,55	disease	0,65	3	neutral	0,94	neutral	0,15	deleterious	1	deleterious	0,76	low_impact	-1,58	medium_impact	-0,14	high_impact	2,22	0,17	0,8	20,53	23,72	N	0,44	N	0,54	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14927	14927	A	G	MI.8704	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	181	61	T	A	Acc/Gcc	-4,4	0	0,02	benign	0	neutral	0,88	neutral	4,69	neutral	-0,27	neutral	-1,94	medium_impact	2,95	neutral	0,95	neutral	0,5	deleterious	2,05	16,52	0,31	0,45	neutral	0,31	neutral	0,37	neutral	0,5	neutral	0,43	1	neutral	0,12	deleterious	0,94	neutral	-3	neutral	0,12	high_impact	2,07	medium_impact	0,69	medium_impact	1,49	0,24	0,8	21,58	46,35	N	0,25	N	0,8	polymorphism	1	0,01	rs201551481	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14927	14927	A	C	MI.8705	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	181	61	T	P	Acc/Ccc	-4,4	0	0,02	benign	0,35	neutral	0,33	neutral	4,61	neutral	-0,19	deleterious	-3,19	high_impact	3,85	neutral	0,93	neutral	0,29	deleterious	3,56	23,1	0,05	0,35	disease	0,64	disease	0,77	disease	0,63	disease	0,66	3	neutral	0,61	deleterious	0,49	neutral	-2	deleterious	0,5	medium_impact	-0,48	medium_impact	0,06	high_impact	2,3	0,18	0,8	21,58	46,35	N	0,32	N	0,95	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14927	14927	A	T	MI.8706	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	181	61	T	S	Acc/Tcc	-4,4	0	0,02	benign	0,04	neutral	0,81	neutral	4,67	neutral	0,89	neutral	-1,25	neutral_impact	0,8	neutral	0,96	neutral	0,67	deleterious	0,71	8,9	0,36	0,5	neutral	0,41	neutral	0,31	neutral	0,21	neutral	0,46	1	neutral	0,12	deleterious	0,89	neutral	-6	neutral	0,17	medium_impact	0,56	medium_impact	0,56	medium_impact	-0,47	0,36	0,8	21,58	46,35	N	0,28	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14928	14928	C	T	MI.8707	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	182	61	T	I	aCc/aTc	0,64	0	0	benign	0,08	neutral	0,69	neutral	4,6	neutral	-1,37	neutral	-2,18	medium_impact	2,29	neutral	0,93	neutral	0,45	deleterious	3,55	23,1	0,17	0,45	neutral	0,31	disease	0,78	neutral	0,28	neutral	0,5	0	neutral	0,21	deleterious	0,81	neutral	-3	neutral	0,24	medium_impact	0,26	medium_impact	0,41	medium_impact	0,89	0,49	0,8	21,58	46,35	N	0,24	N	0,8	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14928	14928	C	A	MI.8708	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	182	61	T	N	aCc/aAc	0,64	0	0	benign	0,43	neutral	0,52	neutral	4,67	neutral	-0,89	neutral	-2,45	medium_impact	2,92	neutral	0,92	neutral	0,41	deleterious	3,21	22,7	0,33	0,5	disease	0,56	disease	0,7	disease	0,51	disease	0,51	0	neutral	0,44	deleterious	0,55	neutral	-3	deleterious	0,46	medium_impact	-0,62	medium_impact	0,24	medium_impact	1,46	0,53	0,8	21,58	46,35	N	0,28	N	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14928	14928	C	G	MI.8709	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	182	61	T	S	aCc/aGc	0,64	0	0	benign	0,04	neutral	0,81	neutral	4,67	neutral	0,89	neutral	-1,25	neutral_impact	0,8	neutral	0,96	neutral	0,67	deleterious	0,34	6,09	0,36	0,5	neutral	0,41	neutral	0,31	neutral	0,21	neutral	0,46	1	neutral	0,12	deleterious	0,89	neutral	-6	neutral	0,17	medium_impact	0,56	medium_impact	0,56	medium_impact	-0,47	0,36	0,8	21,58	46,35	N	0,26	N	0,25	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8936	8936	T	C	MI.871	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	410	137	L	P	cTt/cCt	-0,1	0	0	probably_damaging	1	deleterious	0	neutral	3,61	deleterious	-6,49	deleterious	-6,33	high_impact	4,61	damaging	0,28	damaging	0,11	deleterious	3,89	23,5	0,17	0,65	neutral	0,46	disease	0,69	disease	0,75	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,6	low_impact	-1,4	high_impact	2,85	0,59	0,9	49,56	8,85	P	0,73	P	1	disease_causing	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14930	14930	G	C	MI.8710	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	184	62	A	P	Gcc/Ccc	-4,63	0	0	probably_damaging	1	neutral	0,21	neutral	3,64	deleterious	-5,8	deleterious	-4,15	high_impact	4,88	neutral	0,84	neutral	0,29	deleterious	3,57	23,1	0,05	0,35	disease	0,9	disease	0,81	disease	0,8	disease	0,66	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,09	high_impact	3,24	0,41	0,8	57,11	8,72	P	0,74	P	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14930	14930	G	T	MI.8711	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	184	62	A	S	Gcc/Tcc	-4,63	0	0	probably_damaging	0,99	neutral	0,43	neutral	3,67	deleterious	-5,54	neutral	-2,49	high_impact	3,77	neutral	0,83	neutral	0,47	deleterious	2,02	16,34	0,18	0,45	disease	0,76	disease	0,8	disease	0,6	disease	0,65	3	deleterious	0,99	neutral	0,22	deleterious	2	deleterious	0,87	low_impact	-2,59	medium_impact	0,16	high_impact	2,23	0,34	0,8	57,11	8,72	N	0,33	N	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14930	14930	G	A	MI.8712	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	184	62	A	T	Gcc/Acc	-4,63	0	0	probably_damaging	0,99	neutral	0,41	neutral	3,66	deleterious	-6,51	deleterious	-3,31	high_impact	4,54	neutral	0,91	neutral	0,45	deleterious	2,58	20	0,12	0,4	disease	0,81	disease	0,8	disease	0,64	disease	0,64	3	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,87	low_impact	-2,59	medium_impact	0,14	high_impact	2,93	0,69	0,85	57,11	8,72	N	0,52	P	0,79	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14931	14931	C	T	MI.8713	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	185	62	A	V	gCc/gTc	9,13	1	0	probably_damaging	0,99	neutral	0,51	neutral	3,64	deleterious	-7,47	deleterious	-3,31	high_impact	5,57	neutral	0,77	neutral	0,5	deleterious	2,85	21,6	0,11	0,4	disease	0,87	disease	0,82	disease	0,69	disease	0,62	2	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,86	low_impact	-2,59	medium_impact	0,23	high_impact	3,86	0,64	0,8	57,11	8,72	P	0,76	P	0,84	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14931	14931	C	A	MI.8714	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	185	62	A	D	gCc/gAc	9,13	1	0	probably_damaging	1	neutral	0,23	neutral	3,61	deleterious	-8,41	deleterious	-4,97	high_impact	5,57	neutral	0,8	neutral	0,39	deleterious	4,27	24	0,05	0,35	disease	0,92	disease	0,9	disease	0,79	disease	0,64	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,06	high_impact	3,86	0,31	0,8	57,11	8,72	P	0,76	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14931	14931	C	G	MI.8715	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	185	62	A	G	gCc/gGc	9,13	1	0	probably_damaging	0,98	neutral	0,34	neutral	3,65	deleterious	-5,51	deleterious	-3,32	high_impact	4,33	neutral	0,82	neutral	0,51	deleterious	2,16	17,26	0,18	0,45	disease	0,82	disease	0,78	disease	0,7	disease	0,66	3	neutral	0,98	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-2,31	medium_impact	0,07	high_impact	2,74	0,52	0,8	57,11	8,72	P	0,66	P	0,83	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14933	14933	T	G	MI.8716	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	187	63	F	V	Ttt/Gtt	-6,01	0	0	probably_damaging	0,99	neutral	0,51	neutral	3,76	deleterious	-5,57	deleterious	-5,82	high_impact	4,9	neutral	0,83	damaging	0,08	deleterious	3,67	23,2	0,11	0,4	disease	0,87	disease	0,72	disease	0,75	disease	0,65	3	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-2,59	medium_impact	0,23	high_impact	3,26	0,12	0,8	56,58	8,88	P	0,66	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14933	14933	T	A	MI.8717	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	187	63	F	I	Ttt/Att	-6,01	0	0	probably_damaging	0,98	neutral	0,41	neutral	3,75	deleterious	-5,74	deleterious	-4,99	high_impact	5,25	neutral	0,88	damaging	0,07	deleterious	2,67	20,6	0,16	0,45	disease	0,87	disease	0,68	disease	0,76	disease	0,66	3	deleterious	0,98	neutral	0,22	deleterious	2	deleterious	0,84	low_impact	-2,31	medium_impact	0,14	high_impact	3,57	0,23	0,8	56,58	8,88	P	0,67	P	0,97	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14933	14933	T	C	MI.8718	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	187	63	F	L	Ttt/Ctt	-6,01	0	0	probably_damaging	0,98	neutral	0,65	neutral	3,78	deleterious	-4,26	deleterious	-4,99	high_impact	4,9	neutral	0,86	damaging	0,06	deleterious	2,16	17,22	0,19	0,45	disease	0,76	disease	0,6	disease	0,73	disease	0,69	4	neutral	0,97	neutral	0,34	deleterious	2	deleterious	0,82	low_impact	-2,31	medium_impact	0,37	high_impact	3,26	0,27	0,8	56,58	8,88	P	0,61	P	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14934	14934	T	C	MI.8719	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	188	63	F	S	tTt/tCt	7,3	1	0	probably_damaging	1	neutral	0,41	neutral	3,75	deleterious	-6,32	deleterious	-6,65	high_impact	5,59	neutral	0,85	damaging	0,06	deleterious	3,72	23,3	0,04	0,35	disease	0,88	disease	0,74	disease	0,73	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,14	high_impact	3,88	0,09	0,8	56,58	8,88	P	0,73	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8936	8936	T	A	MI.872	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	410	137	L	H	cTt/cAt	-0,1	0	0	probably_damaging	1	deleterious	0	neutral	3,61	deleterious	-6,53	deleterious	-6,31	high_impact	4,61	damaging	0,44	damaging	0,09	deleterious	4,11	23,7	0,16	0,65	disease	0,92	disease	0,73	disease	0,81	disease	0,84	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,86	low_impact	-3,6	low_impact	-1,4	high_impact	2,85	0,52	0,9	49,56	8,85	P	0,52	P	0,97	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14934	14934	T	A	MI.8720	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	188	63	F	Y	tTt/tAt	7,3	1	0	probably_damaging	0,98	neutral	1	neutral	4,31	neutral	0,08	neutral	-2,49	high_impact	3,73	neutral	0,9	damaging	0,07	deleterious	2,31	18,22	0,25	0,45	neutral	0,43	disease	0,57	disease	0,67	disease	0,52	0	neutral	0,98	deleterious	0,51	deleterious	2	deleterious	0,76	low_impact	-2,31	high_impact	1,85	high_impact	2,19	0,29	0,8	56,58	8,88	N	0,49	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14934	14934	T	G	MI.8721	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	188	63	F	C	tTt/tGt	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	3,74	deleterious	-6,9	deleterious	-6,65	high_impact	5,59	neutral	0,86	damaging	0,06	deleterious	3,94	23,6	0,07	0,35	disease	0,96	disease	0,69	disease	0,77	disease	0,7	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,14	high_impact	3,88	0,07	0,8	56,58	8,88	P	0,69	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14935	14935	T	A	MI.8722	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	189	63	F	L	ttT/ttA	5,69	1	0	probably_damaging	0,98	neutral	0,65	neutral	3,78	deleterious	-4,26	deleterious	-4,99	high_impact	4,9	neutral	0,86	damaging	0,06	deleterious	2,61	20,3	0,19	0,45	disease	0,76	disease	0,6	disease	0,73	disease	0,69	4	neutral	0,97	neutral	0,34	deleterious	2	deleterious	0,82	low_impact	-2,31	medium_impact	0,37	high_impact	3,26	0,27	0,8	56,58	8,88	P	0,73	P	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14935	14935	T	G	MI.8723	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	189	63	F	L	ttT/ttG	5,69	1	0	probably_damaging	0,98	neutral	0,65	neutral	3,78	deleterious	-4,26	deleterious	-4,99	high_impact	4,9	neutral	0,86	damaging	0,06	deleterious	2,46	19,21	0,19	0,45	disease	0,76	disease	0,6	disease	0,73	disease	0,69	4	neutral	0,97	neutral	0,34	deleterious	2	deleterious	0,82	low_impact	-2,31	medium_impact	0,37	high_impact	3,26	0,27	0,8	56,58	8,88	P	0,72	P	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14936	14936	T	C	MI.8724	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	190	64	S	P	Tca/Cca	-2,8	0	0	probably_damaging	0,98	neutral	0,2	neutral	4,54	deleterious	-3,73	deleterious	-3,94	high_impact	4,29	neutral	0,88	damaging	0,1	deleterious	2,12	17	0,05	0,35	disease	0,69	disease	0,73	disease	0,69	disease	0,64	3	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-2,31	medium_impact	-0,1	high_impact	2,7	0,2	0,8	41,32	12,1	N	0,42	N	1	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14936	14936	T	G	MI.8725	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	190	64	S	A	Tca/Gca	-2,8	0	0	probably_damaging	0,92	neutral	0,53	neutral	4,73	neutral	-1,73	neutral	-2,33	medium_impact	2,13	neutral	0,92	damaging	0,21	neutral	1,69	14,37	0,2	0,45	neutral	0,35	neutral	0,37	neutral	0,45	neutral	0,41	2	neutral	0,91	neutral	0,31	deleterious	1	deleterious	0,57	low_impact	-1,72	medium_impact	0,25	medium_impact	0,74	0,35	0,8	41,32	12,1	N	0,27	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14936	14936	T	A	MI.8726	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	190	64	S	T	Tca/Aca	-2,8	0	0	possibly_damaging	0,86	neutral	0,39	neutral	4,61	neutral	-0,57	neutral	-2,23	medium_impact	2,86	neutral	0,86	damaging	0,16	neutral	1,68	14,32	0,15	0,4	neutral	0,47	neutral	0,49	disease	0,54	neutral	0,28	4	neutral	0,87	neutral	0,27	NA	0	deleterious	0,67	low_impact	-1,47	medium_impact	0,12	medium_impact	1,4	0,34	0,8	41,32	12,1	N	0,29	N	0,7	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14937	14937	C	G	MI.8727	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	191	64	S	W	tCa/tGa	2,25	0,93	0	probably_damaging	1	neutral	0,19	neutral	4,53	neutral	-1,25	deleterious	-5,56	high_impact	3,9	neutral	0,89	damaging	0,13	deleterious	4,16	23,8	0,06	0,35	disease	0,87	disease	0,8	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,12	high_impact	2,35	0,14	0,8	41,32	12,1	N	0,42	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14937	14937	C	T	MI.8728	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	191	64	S	L	tCa/tTa	2,25	0,93	0	probably_damaging	0,99	neutral	0,65	neutral	4,56	neutral	-0,76	deleterious	-4,72	high_impact	3,81	neutral	0,88	damaging	0,13	deleterious	2,9	21,8	0,07	0,35	neutral	0,33	disease	0,74	disease	0,55	neutral	0,48	0	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,72	low_impact	-2,59	medium_impact	0,37	high_impact	2,27	0,42	0,8	41,32	12,1	N	0,36	N	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14939	14939	T	C	MI.8729	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	193	65	S	P	Tca/Cca	-4,4	0	0	benign	0,02	neutral	0,2	neutral	4,02	deleterious	-5,13	deleterious	-4,17	high_impact	5,58	neutral	0,94	damaging	0,08	deleterious	3,53	23,1	0,04	0,35	disease	0,84	disease	0,69	disease	0,82	disease	0,69	4	neutral	0,79	deleterious	0,59	neutral	-2	neutral	0,32	medium_impact	0,85	medium_impact	-0,1	high_impact	3,87	0,2	0,8	57,11	8,76	P	0,6	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8938	8938	A	G	MI.873	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	412	138	I	V	Atc/Gtc	-8,66	0	0	probably_damaging	0,93	neutral	0,21	neutral	4,37	neutral	-0,12	neutral	-0,84	low_impact	0,9	neutral	0,88	neutral	0,69	deleterious	3,04	22,3	0,71	0,75	neutral	0,34	neutral	0,34	neutral	0,44	neutral	0,43	1	neutral	0,95	neutral	0,14	neutral	-2	deleterious	0,64	low_impact	-1,82	medium_impact	-0,03	medium_impact	-0,33	0,55	0,9	44,69	8,06	N	0,44	N	0,77	disease_causing	0,72	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14939	14939	T	G	MI.8730	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	193	65	S	A	Tca/Gca	-4,4	0	0	benign	0,2	neutral	0,51	neutral	4,07	deleterious	-3,63	deleterious	-2,5	high_impact	4,48	neutral	0,96	damaging	0,14	deleterious	1,88	15,44	0,18	0,45	disease	0,59	neutral	0,41	disease	0,72	disease	0,59	2	neutral	0,39	deleterious	0,66	neutral	-2	neutral	0,27	medium_impact	-0,17	medium_impact	0,23	high_impact	2,87	0,35	0,8	57,11	8,76	N	0,38	N	0,46	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14939	14939	T	A	MI.8731	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	193	65	S	T	Tca/Aca	-4,4	0	0	benign	0,21	neutral	0,39	neutral	4,07	deleterious	-3,56	deleterious	-2,5	high_impact	4,54	neutral	0,94	damaging	0,1	deleterious	1,9	15,6	0,15	0,45	disease	0,55	disease	0,55	disease	0,65	disease	0,63	3	neutral	0,53	deleterious	0,59	neutral	-2	neutral	0,29	medium_impact	-0,19	medium_impact	0,12	high_impact	2,93	0,55	0,8	57,11	8,76	N	0,37	N	0,7	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14940	14940	C	T	MI.8732	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	194	65	S	L	tCa/tTa	5,69	1	0	probably_damaging	0,96	neutral	0,65	neutral	4,04	deleterious	-4,72	deleterious	-5	high_impact	4,68	neutral	0,95	damaging	0,06	deleterious	4,46	24,2	0,04	0,35	disease	0,79	disease	0,72	disease	0,7	disease	0,67	3	neutral	0,95	neutral	0,35	deleterious	2	deleterious	0,8	low_impact	-2,02	medium_impact	0,37	high_impact	3,06	0,32	0,8	57,11	8,76	P	0,62	P	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14940	14940	C	G	MI.8733	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	194	65	S	W	tCa/tGa	5,69	1	0	probably_damaging	1	neutral	0,19	neutral	4	deleterious	-7,86	deleterious	-5,84	high_impact	5,58	neutral	0,98	damaging	0,1	deleterious	4,21	23,9	0,06	0,35	disease	0,88	disease	0,77	disease	0,75	disease	0,65	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,12	high_impact	3,87	0,09	0,8	57,11	8,76	P	0,71	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14942	14942	A	C	MI.8734	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	196	66	I	L	Atc/Ctc	-4,86	0	0	benign	0,02	neutral	0,65	neutral	4,66	neutral	-0,51	neutral	-1,59	low_impact	1,81	neutral	0,84	neutral	0,54	deleterious	1,86	15,35	0,27	0,45	neutral	0,42	neutral	0,44	neutral	0,43	neutral	0,43	1	neutral	0,31	deleterious	0,82	neutral	-6	neutral	0,2	medium_impact	0,85	medium_impact	0,37	medium_impact	0,45	0,44	0,8	23,68	38,89	N	0,27	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14942	14942	A	G	MI.8735	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	196	66	I	V	Atc/Gtc	-4,86	0	0	benign	0	neutral	0,53	neutral	5,06	neutral	1,58	neutral	0,49	neutral_impact	-1,11	neutral	0,96	neutral	0,9	neutral	-1,61	0	0,39	0,5	neutral	0,2	neutral	0,04	neutral	0,24	neutral	0,2	6	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	0,25	low_impact	-2,2	0,2	0,8	23,68	38,89	N	0,41	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14942	14942	A	T	MI.8736	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	196	66	I	F	Atc/Ttc	-4,86	0	0	benign	0,16	neutral	0,7	neutral	4,55	neutral	-2,17	deleterious	-3,29	high_impact	3,81	neutral	0,85	neutral	0,58	deleterious	2,07	16,63	0,1	0,4	disease	0,75	disease	0,73	disease	0,62	disease	0,7	4	neutral	0,18	deleterious	0,77	neutral	-2	deleterious	0,44	medium_impact	-0,06	medium_impact	0,42	high_impact	2,27	0,33	0,8	23,68	38,89	N	0,28	N	0,92	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14943	14943	T	G	MI.8737	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	197	66	I	S	aTc/aGc	0,87	0,72	0	benign	0,21	neutral	0,45	neutral	4,54	neutral	-2,28	deleterious	-4,29	high_impact	3,6	neutral	0,84	neutral	0,55	deleterious	2,49	19,41	0,03	0,35	disease	0,81	disease	0,74	disease	0,58	disease	0,69	4	neutral	0,46	deleterious	0,62	neutral	-2	deleterious	0,46	medium_impact	-0,19	medium_impact	0,18	high_impact	2,08	0,05	0,8	23,68	38,89	N	0,3	N	0,94	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14943	14943	T	C	MI.8738	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	197	66	I	T	aTc/aCc	0,87	0,72	0	benign	0,08	neutral	0,39	neutral	4,68	neutral	0,18	deleterious	-2,79	medium_impact	3,12	neutral	0,84	neutral	0,54	neutral	1,58	13,72	0,06	0,35	disease	0,67	disease	0,5	neutral	0,5	disease	0,52	0	neutral	0,56	deleterious	0,66	neutral	-3	neutral	0,32	medium_impact	0,26	medium_impact	0,12	medium_impact	1,64	0,12	0,8	23,68	38,89	N	0,31	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14943	14943	T	A	MI.8739	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	197	66	I	N	aTc/aAc	0,87	0,72	0	possibly_damaging	0,6	neutral	0,31	neutral	4,52	deleterious	-3,77	deleterious	-5,12	high_impact	3,81	neutral	0,83	neutral	0,56	deleterious	2,79	21,3	0,06	0,35	disease	0,89	disease	0,82	disease	0,62	disease	0,69	4	neutral	0,71	neutral	0,36	deleterious	1	deleterious	0,72	medium_impact	-0,9	medium_impact	0,03	high_impact	2,27	0,09	0,8	23,68	38,89	N	0,35	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8938	8938	A	C	MI.874	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	412	138	I	L	Atc/Ctc	-8,66	0	0	probably_damaging	0,93	neutral	0,1	neutral	4,22	neutral	-1,24	neutral	-1,76	medium_impact	2,21	neutral	0,72	neutral	0,46	deleterious	3,82	23,4	0,48	0,65	neutral	0,31	disease	0,55	disease	0,63	disease	0,64	3	neutral	0,97	neutral	0,09	deleterious	1	deleterious	0,65	low_impact	-1,82	medium_impact	-0,25	medium_impact	0,8	0,7	0,9	44,69	8,06	N	0,38	N	0,83	disease_causing	0,85	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14944	14944	C	A	MI.8740	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	198	66	I	M	atC/atA	7,3	0,98	0,08	benign	0,43	neutral	0,22	neutral	4,56	neutral	-1,65	neutral	-1,77	medium_impact	2,29	neutral	0,84	neutral	0,47	deleterious	2,12	16,98	0,2	0,45	disease	0,7	neutral	0,47	neutral	0,42	disease	0,57	1	neutral	0,75	neutral	0,4	neutral	-3	deleterious	0,5	medium_impact	-0,62	medium_impact	-0,08	medium_impact	0,89	0,29	0,8	23,68	38,89	P	0,57	P	0,8	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14944	14944	C	G	MI.8741	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	198	66	I	M	atC/atG	7,3	0,98	0,08	benign	0,43	neutral	0,22	neutral	4,56	neutral	-1,65	neutral	-1,77	medium_impact	2,29	neutral	0,84	neutral	0,47	neutral	1,64	14,07	0,2	0,45	disease	0,7	neutral	0,47	neutral	0,42	disease	0,57	1	neutral	0,75	neutral	0,4	neutral	-3	deleterious	0,5	medium_impact	-0,62	medium_impact	-0,08	medium_impact	0,89	0,29	0,8	23,68	38,89	P	0,58	P	0,8	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14945	14945	G	C	MI.8742	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	199	67	A	P	Gcc/Ccc	-16,1	0	0	probably_damaging	1	neutral	0,2	neutral	4,59	neutral	-2,14	deleterious	-3,18	high_impact	4,29	neutral	0,84	neutral	0,39	deleterious	3,71	23,3	0,03	0,35	disease	0,52	disease	0,89	disease	0,69	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,1	high_impact	2,7	0,48	0,8	22,37	25,43	N	0,43	N	0,79	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14945	14945	G	A	MI.8743	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	199	67	A	T	Gcc/Acc	-16,1	0	0	probably_damaging	1	neutral	0,42	neutral	4,67	neutral	-0,29	neutral	-1,45	low_impact	1,05	neutral	0,94	neutral	0,97	neutral	1,26	12,07	0,1	0,4	neutral	0,19	neutral	0,31	neutral	0,27	neutral	0,43	1	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,68	low_impact	-3,53	medium_impact	0,15	medium_impact	-0,24	0,63	0,8	22,37	25,43	N	0,41	N	0	polymorphism	1	0,02	.	.	.	.	.	.	COSM1155579	.	.	.	.	.	.	.	.
chrM	14945	14945	G	T	MI.8744	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	199	67	A	S	Gcc/Tcc	-16,1	0	0	probably_damaging	1	neutral	0,47	neutral	4,65	neutral	-0,13	neutral	-1,57	low_impact	1,5	neutral	0,9	neutral	0,83	deleterious	2,03	16,39	0,15	0,4	neutral	0,27	disease	0,71	neutral	0,23	neutral	0,2	6	deleterious	1	neutral	0,24	neutral	-2	deleterious	0,76	low_impact	-3,53	medium_impact	0,19	medium_impact	0,17	0,49	0,8	22,37	25,43	N	0,31	N	0,5	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14946	14946	C	G	MI.8745	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	200	67	A	G	gCc/gGc	-0,04	0	0	probably_damaging	0,99	neutral	0,34	neutral	4,6	neutral	-1,55	deleterious	-2,8	medium_impact	3,5	neutral	0,82	neutral	0,59	deleterious	2,27	17,94	0,14	0,4	neutral	0,43	disease	0,78	disease	0,54	disease	0,62	2	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,76	low_impact	-2,59	medium_impact	0,07	medium_impact	1,98	0,65	0,8	22,37	25,43	N	0,32	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14946	14946	C	T	MI.8746	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	200	67	A	V	gCc/gTc	-0,04	0	0	probably_damaging	1	neutral	0,63	neutral	4,63	neutral	-0,99	neutral	-2,03	low_impact	1,14	neutral	0,91	neutral	0,77	deleterious	2,97	22,1	0,06	0,35	neutral	0,37	disease	0,66	neutral	0,32	neutral	0,2	6	deleterious	1	neutral	0,32	neutral	-2	deleterious	0,74	low_impact	-3,53	medium_impact	0,35	medium_impact	-0,16	0,64	0,8	22,37	25,43	N	0,24	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14946	14946	C	A	MI.8747	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	200	67	A	D	gCc/gAc	-0,04	0	0	probably_damaging	1	neutral	0,23	neutral	4,62	neutral	-0,63	deleterious	-3,75	high_impact	3,84	neutral	0,8	neutral	0,47	deleterious	4,44	24,2	0,02	0,35	neutral	0,32	disease	0,9	disease	0,59	disease	0,65	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	-0,06	high_impact	2,29	0,35	0,8	22,37	25,43	N	0,35	N	0,92	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14948	14948	C	G	MI.8748	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	202	68	H	D	Cac/Gac	-6,01	0	0	probably_damaging	0,99	neutral	0,21	neutral	4,6	neutral	-2,98	deleterious	-7,4	high_impact	4,63	neutral	0,84	damaging	0,08	deleterious	2,1	16,84	0,04	0,35	disease	0,79	disease	0,88	disease	0,71	disease	0,67	3	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-2,59	medium_impact	-0,09	high_impact	3,01	0,28	0,8	56,05	8,33	N	0,44	N	0,98	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14948	14948	C	A	MI.8749	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	202	68	H	N	Cac/Aac	-6,01	0	0	probably_damaging	0,98	neutral	0,31	neutral	4,56	neutral	-0,83	deleterious	-5,73	medium_impact	3,5	neutral	0,85	damaging	0,1	deleterious	2,05	16,51	0,13	0,4	disease	0,76	disease	0,87	disease	0,65	disease	0,66	3	deleterious	0,98	neutral	0,17	deleterious	1	deleterious	0,83	low_impact	-2,31	medium_impact	0,03	medium_impact	1,98	0,28	0,8	56,05	8,33	N	0,26	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8938	8938	A	T	MI.875	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	412	138	I	F	Atc/Ttc	-8,66	0	0	probably_damaging	0,99	neutral	0,15	neutral	4,13	neutral	-2,84	deleterious	-3,52	high_impact	3,9	neutral	0,72	neutral	0,45	deleterious	3,82	23,4	0,41	0,65	disease	0,67	disease	0,68	disease	0,69	disease	0,67	3	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,8	low_impact	-2,65	medium_impact	-0,13	high_impact	2,25	0,77	0,9	44,69	8,06	N	0,39	N	0,97	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14948	14948	C	T	MI.8750	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	202	68	H	Y	Cac/Tac	-6,01	0	0	probably_damaging	0,97	neutral	1	neutral	4,63	neutral	-2,79	deleterious	-4,94	medium_impact	2,96	neutral	0,9	damaging	0,09	deleterious	1,87	15,38	0,06	0,35	disease	0,51	disease	0,88	disease	0,53	neutral	0,46	1	neutral	0,97	deleterious	0,52	deleterious	1	deleterious	0,81	low_impact	-2,14	high_impact	1,85	medium_impact	1,49	0,22	0,8	56,05	8,33	N	0,19	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14949	14949	A	C	MI.8751	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	203	68	H	P	cAc/cCc	2,25	0,95	0	probably_damaging	0,99	neutral	0,2	neutral	4,52	deleterious	-3,42	deleterious	-8,24	high_impact	5,08	neutral	0,9	damaging	0,07	neutral	1,5	13,29	0,02	0,35	disease	0,87	disease	0,89	disease	0,79	disease	0,64	3	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-2,59	medium_impact	-0,1	high_impact	3,42	0,19	0,8	56,05	8,33	P	0,7	P	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14949	14949	A	G	MI.8752	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	203	68	H	R	cAc/cGc	2,25	0,95	0	probably_damaging	0,97	neutral	0,35	neutral	4,58	neutral	-2,42	deleterious	-6,58	high_impact	3,85	neutral	0,86	damaging	0,07	neutral	1,15	11,5	0,05	0,35	neutral	0,44	disease	0,88	disease	0,63	disease	0,68	4	neutral	0,97	neutral	0,19	deleterious	2	deleterious	0,81	low_impact	-2,14	medium_impact	0,08	high_impact	2,3	0,31	0,8	56,05	8,33	N	0,42	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14949	14949	A	T	MI.8753	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	203	68	H	L	cAc/cTc	2,25	0,95	0	probably_damaging	0,97	neutral	0,65	neutral	4,54	neutral	0,53	deleterious	-9,04	high_impact	3,96	neutral	0,88	damaging	0,08	deleterious	2,06	16,61	0,02	0,35	disease	0,72	disease	0,91	disease	0,67	disease	0,69	4	neutral	0,97	neutral	0,34	deleterious	2	deleterious	0,85	low_impact	-2,14	medium_impact	0,37	high_impact	2,4	0,14	0,8	56,05	8,33	N	0,38	N	0,92	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14950	14950	C	A	MI.8754	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	204	68	H	Q	caC/caA	6,84	0,99	0	probably_damaging	0,98	neutral	0,29	neutral	4,57	neutral	-2,13	deleterious	-6,57	high_impact	4,63	neutral	0,88	damaging	0,08	deleterious	2,07	16,64	0,08	0,35	disease	0,7	disease	0,84	disease	0,65	disease	0,68	4	deleterious	0,98	neutral	0,16	deleterious	2	deleterious	0,82	low_impact	-2,31	medium_impact	0,01	high_impact	3,01	0,43	0,8	56,05	8,33	P	0,57	P	0,94	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14950	14950	C	G	MI.8755	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	204	68	H	Q	caC/caG	6,84	0,99	0	probably_damaging	0,98	neutral	0,29	neutral	4,57	neutral	-2,13	deleterious	-6,57	high_impact	4,63	neutral	0,88	damaging	0,08	neutral	1,67	14,21	0,08	0,35	disease	0,7	disease	0,84	disease	0,65	disease	0,68	4	deleterious	0,98	neutral	0,16	deleterious	2	deleterious	0,82	low_impact	-2,31	medium_impact	0,01	high_impact	3,01	0,43	0,8	56,05	8,33	P	0,57	P	0,94	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14951	14951	A	G	MI.8756	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	205	69	I	V	Atc/Gtc	-1,65	0	0	possibly_damaging	0,87	neutral	0,51	neutral	4,02	deleterious	-3,39	neutral	-0,71	high_impact	4,24	neutral	0,91	neutral	0,49	neutral	0,94	10,34	0,26	0,45	neutral	0,39	disease	0,51	disease	0,59	disease	0,62	2	neutral	0,86	neutral	0,32	deleterious	1	deleterious	0,59	low_impact	-1,5	medium_impact	0,23	high_impact	2,66	0,43	0,8	56,32	8,73	N	0,42	N	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14951	14951	A	T	MI.8757	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	205	69	I	F	Atc/Ttc	-1,65	0	0	probably_damaging	0,99	neutral	0,71	neutral	3,96	deleterious	-4,72	deleterious	-3,1	high_impact	4,58	neutral	0,85	neutral	0,36	deleterious	1,97	16,02	0,05	0,35	disease	0,79	disease	0,85	disease	0,69	disease	0,67	3	deleterious	0,99	neutral	0,36	deleterious	2	deleterious	0,85	low_impact	-2,59	medium_impact	0,43	high_impact	2,97	0,62	0,8	56,32	8,73	N	0,41	N	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14951	14951	A	C	MI.8758	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	205	69	I	L	Atc/Ctc	-1,65	0	0	probably_damaging	0,95	neutral	0,66	neutral	4,13	neutral	-2,01	neutral	-1,46	medium_impact	2,86	neutral	0,84	neutral	0,35	neutral	1,72	14,54	0,15	0,4	neutral	0,38	disease	0,67	disease	0,53	neutral	0,45	1	neutral	0,94	neutral	0,36	deleterious	1	deleterious	0,52	low_impact	-1,92	medium_impact	0,38	medium_impact	1,4	0,63	0,8	56,32	8,73	N	0,2	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14952	14952	T	C	MI.8759	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	206	69	I	T	aTc/aCc	8,44	1	0	probably_damaging	1	neutral	0,4	neutral	3,96	deleterious	-4,63	deleterious	-3,67	medium_impact	2,84	neutral	0,85	neutral	0,42	deleterious	3,29	22,8	0,02	0,35	disease	0,63	disease	0,69	neutral	0,49	neutral	0,18	6	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,82	low_impact	-3,53	medium_impact	0,13	medium_impact	1,39	0,27	0,8	56,32	8,73	N	0,52	P	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8939	8939	T	C	MI.876	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	413	138	I	T	aTc/aCc	7,07	1	0	probably_damaging	0,99	neutral	0,25	neutral	4,18	neutral	-1,8	deleterious	-4,32	medium_impact	2,93	neutral	0,84	neutral	0,56	deleterious	3,38	22,9	0,42	0,65	neutral	0,38	disease	0,61	disease	0,59	neutral	0,48	0	deleterious	0,99	neutral	0,13	deleterious	1	deleterious	0,75	low_impact	-2,65	medium_impact	0,02	medium_impact	1,41	0,63	0,9	44,69	8,06	P	0,51	P	0,99	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14952	14952	T	G	MI.8760	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	206	69	I	S	aTc/aGc	8,44	1	0	probably_damaging	1	neutral	0,43	neutral	3,94	deleterious	-5,07	deleterious	-4,56	high_impact	4,79	neutral	0,84	neutral	0,38	deleterious	4,18	23,8	0,01	0,35	disease	0,86	disease	0,87	disease	0,66	disease	0,64	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,16	high_impact	3,16	0,33	0,8	56,32	8,73	P	0,78	P	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14952	14952	T	A	MI.8761	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	206	69	I	N	aTc/aAc	8,44	1	0	probably_damaging	1	neutral	0,32	neutral	3,92	deleterious	-6,42	deleterious	-5,4	high_impact	5,48	neutral	0,83	neutral	0,36	deleterious	4,34	24	0,03	0,35	disease	0,92	disease	0,86	disease	0,68	disease	0,61	2	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,05	high_impact	3,78	0,29	0,8	56,32	8,73	P	0,74	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14953	14953	C	A	MI.8762	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	207	69	I	M	atC/atA	2,25	0,98	0	probably_damaging	1	neutral	0,23	neutral	3,95	deleterious	-4,8	neutral	-2,07	high_impact	3,56	neutral	0,83	neutral	0,44	deleterious	3,28	22,8	0,08	0,35	disease	0,75	disease	0,61	disease	0,57	neutral	0,36	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	-0,06	high_impact	2,04	0,52	0,8	56,32	8,73	N	0,47	N	0,83	polymorphism	1	0,06	rs879117423	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14953	14953	C	G	MI.8763	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	207	69	I	M	atC/atG	2,25	0,98	0	probably_damaging	1	neutral	0,23	neutral	3,95	deleterious	-4,8	neutral	-2,07	high_impact	3,56	neutral	0,83	neutral	0,44	deleterious	2,83	21,5	0,08	0,35	disease	0,75	disease	0,61	disease	0,57	neutral	0,36	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	-0,06	high_impact	2,04	0,52	0,8	56,32	8,73	N	0,47	N	0,83	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14954	14954	A	C	MI.8764	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	208	70	T	P	Act/Cct	-3,26	0	0	probably_damaging	0,99	neutral	0,2	neutral	4,6	neutral	-2,43	neutral	-2,04	medium_impact	2,63	neutral	0,84	neutral	0,44	deleterious	3,04	22,3	0,04	0,35	disease	0,58	disease	0,91	disease	0,66	disease	0,78	6	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,88	low_impact	-2,59	medium_impact	-0,1	medium_impact	1,19	0,31	0,8	23,95	54,05	N	0,27	N	0,91	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14954	14954	A	G	MI.8765	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	208	70	T	A	Act/Gct	-3,26	0	0	probably_damaging	0,98	neutral	0,49	neutral	4,67	neutral	-0,5	neutral	0,11	medium_impact	2,17	neutral	0,74	neutral	0,77	neutral	1,68	14,32	0,14	0,4	neutral	0,26	disease	0,62	disease	0,52	disease	0,56	1	deleterious	0,98	neutral	0,26	deleterious	1	deleterious	0,72	low_impact	-2,31	medium_impact	0,21	medium_impact	0,78	0,35	0,8	23,95	54,05	N	0,36	N	0,19	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14954	14954	A	T	MI.8766	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	208	70	T	S	Act/Tct	-3,26	0	0	probably_damaging	0,98	neutral	0,41	neutral	4,71	neutral	0,51	neutral	-0,28	neutral_impact	0,12	neutral	0,84	neutral	0,63	neutral	1,54	13,54	0,19	0,45	neutral	0,35	disease	0,63	neutral	0,22	neutral	0,19	6	deleterious	0,98	neutral	0,22	neutral	-2	deleterious	0,75	low_impact	-2,31	medium_impact	0,14	low_impact	-1,08	0,62	0,8	23,95	54,05	N	0,3	N	0,29	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14955	14955	C	G	MI.8767	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	209	70	T	S	aCt/aGt	3,63	0,99	0	probably_damaging	0,98	neutral	0,41	neutral	4,71	neutral	0,51	neutral	-0,28	neutral_impact	0,12	neutral	0,84	neutral	0,63	neutral	1,74	14,66	0,19	0,45	neutral	0,35	disease	0,63	neutral	0,22	neutral	0,19	6	deleterious	0,98	neutral	0,22	neutral	-2	deleterious	0,75	low_impact	-2,31	medium_impact	0,14	low_impact	-1,08	0,62	0,8	23,95	54,05	N	0,41	N	0,29	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14955	14955	C	A	MI.8768	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	209	70	T	N	aCt/aAt	3,63	0,99	0	probably_damaging	0,99	neutral	0,35	neutral	4,63	neutral	-0,81	neutral	-1,74	medium_impact	2,01	neutral	0,83	neutral	0,63	deleterious	1,91	15,67	0,17	0,45	disease	0,52	disease	0,87	disease	0,52	disease	0,73	5	deleterious	0,99	neutral	0,18	deleterious	1	deleterious	0,83	low_impact	-2,59	medium_impact	0,08	medium_impact	0,63	0,46	0,8	23,95	54,05	N	0,41	N	0,69	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14955	14955	C	T	MI.8769	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	209	70	T	I	aCt/aTt	3,63	0,99	0	probably_damaging	0,99	neutral	0,55	neutral	4,72	neutral	-0,01	neutral	-0,81	low_impact	0,82	neutral	0,82	neutral	0,67	deleterious	3,46	23	0,07	0,35	neutral	0,22	disease	0,85	neutral	0,49	disease	0,68	4	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,76	low_impact	-2,59	medium_impact	0,27	medium_impact	-0,45	0,63	0,8	23,95	54,05	N	0,31	N	0,42	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8939	8939	T	A	MI.877	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	413	138	I	N	aTc/aAc	7,07	1	0	probably_damaging	1	neutral	0,15	neutral	4,1	deleterious	-3,89	deleterious	-6,15	medium_impact	2,19	neutral	0,74	neutral	0,48	deleterious	4,4	24,1	0,27	0,65	disease	0,66	disease	0,73	disease	0,69	disease	0,61	2	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	-0,13	medium_impact	0,78	0,73	0,9	44,69	8,06	N	0,5	N	1	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14957	14957	C	T	MI.8770	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	211	71	R	W	Cga/Tga	-1,65	0	0	probably_damaging	1	neutral	0,19	neutral	4,4	deleterious	-5,73	deleterious	-6,67	high_impact	4,82	neutral	0,84	damaging	0,06	deleterious	5,07	25,3	0,05	0,35	disease	0,63	disease	0,93	disease	0,73	disease	0,77	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,12	high_impact	3,18	0,73	0,85	58,68	8,72	P	0,6	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14957	14957	C	G	MI.8771	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	211	71	R	G	Cga/Gga	-1,65	0	0	probably_damaging	0,99	neutral	0,33	neutral	4,43	neutral	-2,93	deleterious	-5,83	high_impact	4,7	neutral	0,82	damaging	0,06	deleterious	2,51	19,53	0,04	0,35	disease	0,76	disease	0,88	disease	0,71	disease	0,68	4	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-2,59	medium_impact	0,06	high_impact	3,07	0,26	0,8	58,68	8,72	N	0,53	P	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14958	14958	G	A	MI.8772	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	212	71	R	Q	cGa/cAa	3,4	0,99	0	probably_damaging	0,99	neutral	0,29	neutral	4,5	neutral	-1,91	deleterious	-3,33	high_impact	3,75	neutral	0,85	damaging	0,04	deleterious	2,67	20,6	0,09	0,35	disease	0,63	disease	0,87	disease	0,66	disease	0,67	3	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-2,59	medium_impact	0,01	high_impact	2,21	0,74	0,85	58,68	8,72	N	0,5	N	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14958	14958	G	C	MI.8773	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	212	71	R	P	cGa/cCa	3,4	0,99	0	probably_damaging	1	neutral	0,2	neutral	4,41	deleterious	-3,5	deleterious	-5,83	high_impact	4,82	neutral	0,86	damaging	0,04	deleterious	3,81	23,4	0,03	0,35	disease	0,82	disease	0,91	disease	0,81	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,1	high_impact	3,18	0,2	0,8	58,68	8,72	P	0,7	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14958	14958	G	T	MI.8774	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	212	71	R	L	cGa/cTa	3,4	0,99	0	probably_damaging	0,98	neutral	0,65	neutral	4,43	neutral	-2,5	deleterious	-5,84	high_impact	4,47	neutral	0,84	damaging	0,04	deleterious	2,44	19,09	0,04	0,35	disease	0,61	disease	0,94	disease	0,7	disease	0,78	6	deleterious	0,98	neutral	0,34	deleterious	2	deleterious	0,88	low_impact	-2,31	medium_impact	0,37	high_impact	2,87	0,14	0,8	58,68	8,72	N	0,43	N	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14960	14960	G	T	MI.8775	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	214	72	D	Y	Gac/Tac	0,64	0,99	0	probably_damaging	1	neutral	1	neutral	4,36	deleterious	-4,41	deleterious	-7,07	high_impact	4,91	neutral	0,92	damaging	0,11	deleterious	3,87	23,5	0,03	0,35	disease	0,92	disease	0,96	disease	0,8	disease	0,63	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,92	low_impact	-3,53	high_impact	1,85	high_impact	3,26	0,08	0,8	57,11	8,41	P	0,6	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14960	14960	G	A	MI.8776	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	214	72	D	N	Gac/Aac	0,64	0,99	0	probably_damaging	1	neutral	0,31	neutral	4,43	neutral	-2,13	deleterious	-3,57	medium_impact	2,28	neutral	0,88	damaging	0,13	deleterious	3,92	23,5	0,33	0,5	disease	0,53	disease	0,81	disease	0,53	neutral	0,22	6	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,83	low_impact	-3,53	medium_impact	0,03	medium_impact	0,88	0,82	0,85	57,11	8,41	N	0,41	N	0,99	polymorphism	1	0,03	.	.	.	.	.	.	COSM1636968	.	.	.	.	.	.	.	.
chrM	14960	14960	G	C	MI.8777	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	214	72	D	H	Gac/Cac	0,64	0,99	0	probably_damaging	1	neutral	0,54	neutral	4,37	deleterious	-3,77	deleterious	-5,34	high_impact	4,91	neutral	0,91	damaging	0,1	deleterious	3,54	23,1	0,05	0,35	disease	0,82	disease	0,89	disease	0,85	disease	0,72	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,26	high_impact	3,26	0,39	0,8	57,11	8,41	P	0,66	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14961	14961	A	C	MI.8778	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	215	72	D	A	gAc/gCc	3,4	1	0	probably_damaging	1	neutral	0,5	neutral	4,42	neutral	-2,53	deleterious	-6,29	high_impact	5,11	neutral	0,93	damaging	0,13	deleterious	3,35	22,9	0,05	0,35	disease	0,75	disease	0,89	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,22	high_impact	3,45	0,21	0,8	57,11	8,41	P	0,71	P	0,94	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14961	14961	A	G	MI.8779	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	215	72	D	G	gAc/gGc	3,4	1	0	probably_damaging	1	neutral	0,33	neutral	4,38	neutral	-2,44	deleterious	-5,46	high_impact	4,55	neutral	0,92	damaging	0,14	deleterious	3,81	23,4	0,05	0,35	disease	0,75	disease	0,91	disease	0,82	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,06	high_impact	2,94	0,26	0,8	57,11	8,41	P	0,61	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8939	8939	T	G	MI.878	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	413	138	I	S	aTc/aGc	7,07	1	0	probably_damaging	0,99	neutral	0,12	neutral	4,13	neutral	-2,74	deleterious	-5,22	medium_impact	2,22	neutral	0,74	neutral	0,57	deleterious	4,23	23,9	0,26	0,65	disease	0,58	disease	0,75	disease	0,61	disease	0,56	1	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,8	low_impact	-2,65	medium_impact	-0,2	medium_impact	0,81	0,68	0,9	44,69	8,06	N	0,47	N	0,98	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14961	14961	A	T	MI.8780	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	215	72	D	V	gAc/gTc	3,4	1	0	probably_damaging	1	neutral	0,51	neutral	4,38	deleterious	-4,54	deleterious	-7,13	high_impact	5,46	neutral	0,92	damaging	0,12	deleterious	3,59	23,2	0,03	0,35	disease	0,89	disease	0,95	disease	0,78	disease	0,67	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,23	high_impact	3,76	0,06	0,8	57,11	8,41	P	0,7	P	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14962	14962	C	G	MI.8781	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	216	72	D	E	gaC/gaG	8,44	1	0	probably_damaging	0,99	neutral	0,27	neutral	4,61	neutral	-0,68	deleterious	-2,96	medium_impact	3,36	neutral	0,91	damaging	0,13	deleterious	2,16	17,26	0,18	0,45	neutral	0,34	disease	0,87	disease	0,52	neutral	0,47	1	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-2,59	medium_impact	-0,01	medium_impact	1,86	0,51	0,8	57,11	8,41	P	0,55	P	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14962	14962	C	A	MI.8782	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	216	72	D	E	gaC/gaA	8,44	1	0	probably_damaging	0,99	neutral	0,27	neutral	4,61	neutral	-0,68	deleterious	-2,96	medium_impact	3,36	neutral	0,91	damaging	0,13	deleterious	2,53	19,64	0,18	0,45	neutral	0,34	disease	0,87	disease	0,52	neutral	0,47	1	deleterious	0,99	neutral	0,14	deleterious	1	deleterious	0,81	low_impact	-2,59	medium_impact	-0,01	medium_impact	1,86	0,51	0,8	57,11	8,41	P	0,56	P	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14963	14963	G	C	MI.8783	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	217	73	V	L	Gta/Cta	-4,63	0	0	probably_damaging	0,96	neutral	0,65	neutral	4,03	neutral	-2,84	deleterious	-2,52	high_impact	4,32	neutral	0,93	damaging	0,08	neutral	1,63	14,04	0,13	0,4	neutral	0,46	disease	0,81	disease	0,71	disease	0,68	4	neutral	0,95	neutral	0,35	deleterious	2	deleterious	0,8	low_impact	-2,02	medium_impact	0,37	high_impact	2,73	0,46	0,8	55,79	8,15	N	0,3	N	0,69	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14963	14963	G	T	MI.8784	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	217	73	V	L	Gta/Tta	-4,63	0	0	probably_damaging	0,96	neutral	0,65	neutral	4,03	neutral	-2,84	deleterious	-2,52	high_impact	4,32	neutral	0,93	damaging	0,08	neutral	1,73	14,6	0,13	0,4	neutral	0,46	disease	0,81	disease	0,71	disease	0,68	4	neutral	0,95	neutral	0,35	deleterious	2	deleterious	0,8	low_impact	-2,02	medium_impact	0,37	high_impact	2,73	0,46	0,8	55,79	8,15	N	0,3	N	0,69	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14963	14963	G	A	MI.8785	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	217	73	V	M	Gta/Ata	-4,63	0	0	probably_damaging	1	neutral	0,22	neutral	3,94	deleterious	-4,4	deleterious	-2,52	high_impact	3,82	neutral	0,92	damaging	0,11	deleterious	3,56	23,1	0,1	0,4	disease	0,8	disease	0,78	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,08	high_impact	2,28	0,7	0,85	55,79	8,15	N	0,39	N	0,97	polymorphism	1	0,07	.	.	.	.	.	colonic crypts	.	.	.	.	.	.	.	.	.
chrM	14964	14964	T	G	MI.8786	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	218	73	V	G	gTa/gGa	5	1	0	probably_damaging	1	neutral	0,33	neutral	3,91	deleterious	-5,77	deleterious	-5,89	high_impact	4,71	neutral	0,92	damaging	0,11	deleterious	3,71	23,3	0,01	0,35	disease	0,92	disease	0,84	disease	0,74	disease	0,63	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,06	high_impact	3,08	0,2	0,8	55,79	8,15	P	0,73	P	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14964	14964	T	A	MI.8787	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	218	73	V	E	gTa/gAa	5	1	0	probably_damaging	1	neutral	0,28	neutral	3,91	deleterious	-6,21	deleterious	-5,05	high_impact	4,62	neutral	0,91	damaging	0,08	deleterious	4,56	24,4	0,01	0,35	disease	0,93	disease	0,9	disease	0,81	disease	0,63	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0	high_impact	3	0,11	0,8	55,79	8,15	P	0,72	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14964	14964	T	C	MI.8788	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	218	73	V	A	gTa/gCa	5	1	0	probably_damaging	1	neutral	0,51	neutral	3,97	deleterious	-3,97	deleterious	-3,37	high_impact	4,62	neutral	0,93	damaging	0,12	deleterious	3,1	22,5	0,06	0,35	disease	0,77	disease	0,7	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,23	high_impact	3	0,12	0,8	55,79	8,15	P	0,64	P	0,62	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14966	14966	A	G	MI.8789	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	220	74	N	D	Aat/Gat	-6,24	0	0	probably_damaging	0,97	neutral	0,21	neutral	4,56	neutral	0,36	deleterious	-2,88	high_impact	3,71	neutral	0,84	damaging	0,09	deleterious	1,97	16,05	0,49	0,55	neutral	0,38	disease	0,83	disease	0,55	disease	0,63	3	neutral	0,98	neutral	0,12	deleterious	2	deleterious	0,78	low_impact	-2,14	medium_impact	-0,09	high_impact	2,18	0,24	0,8	56,58	8,8	N	0,3	N	0,93	polymorphism	1	0,02	.	.	.	.	.	.	COSM1155581	.	.	.	.	.	.	.	.
chrM	8940	8940	C	G	MI.879	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	414	138	I	M	atC/atG	5,91	1	0	probably_damaging	1	neutral	0,5	neutral	4,19	neutral	-1,61	deleterious	-2,62	low_impact	1,66	neutral	0,79	neutral	0,57	deleterious	3,45	23	0,53	0,65	neutral	0,42	neutral	0,27	neutral	0,41	neutral	0,42	2	deleterious	0,99	neutral	0,25	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,29	medium_impact	0,33	0,83	0,9	44,69	8,06	P	0,49	N	0,75	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14966	14966	A	C	MI.8790	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	220	74	N	H	Aat/Cat	-6,24	0	0	probably_damaging	1	neutral	0,55	neutral	4,51	neutral	-1,78	deleterious	-2,85	high_impact	3,85	neutral	0,9	damaging	0,09	deleterious	2,78	21,3	0,28	0,45	neutral	0,34	disease	0,82	disease	0,6	disease	0,54	1	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,27	high_impact	2,3	0,17	0,8	56,58	8,8	N	0,23	N	0,82	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14966	14966	A	T	MI.8791	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	220	74	N	Y	Aat/Tat	-6,24	0	0	probably_damaging	1	neutral	1	neutral	4,5	deleterious	-3,32	deleterious	-4,85	high_impact	3,98	neutral	0,86	damaging	0,08	deleterious	3,49	23,1	0,06	0,35	disease	0,7	disease	0,92	disease	0,67	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,87	low_impact	-3,53	high_impact	1,85	high_impact	2,42	0,19	0,8	56,58	8,8	N	0,22	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14967	14967	A	T	MI.8792	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	221	74	N	I	aAt/aTt	4,31	0,99	0	probably_damaging	1	neutral	0,4	neutral	4,5	deleterious	-3,07	deleterious	-5,95	high_impact	4,79	neutral	0,86	damaging	0,09	deleterious	3,48	23,1	0,07	0,35	disease	0,65	disease	0,93	disease	0,61	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,13	high_impact	3,16	0,15	0,8	56,58	8,8	P	0,64	P	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14967	14967	A	C	MI.8793	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	221	74	N	T	aAt/aCt	4,31	0,99	0	probably_damaging	0,98	neutral	0,39	neutral	4,56	neutral	-1,41	deleterious	-3,68	high_impact	3,89	neutral	0,86	damaging	0,11	neutral	1,48	13,21	0,25	0,45	neutral	0,43	disease	0,83	disease	0,54	neutral	0,49	0	deleterious	0,98	neutral	0,21	deleterious	2	deleterious	0,8	low_impact	-2,31	medium_impact	0,12	high_impact	2,34	0,23	0,8	56,58	8,8	N	0,47	N	0,78	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14967	14967	A	G	MI.8794	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	221	74	N	S	aAt/aGt	4,31	0,99	0	probably_damaging	0,92	neutral	0,4	neutral	4,58	neutral	-0,97	deleterious	-2,82	medium_impact	2,8	neutral	0,85	damaging	0,18	neutral	1,02	10,79	0,47	0,55	neutral	0,38	disease	0,8	disease	0,55	neutral	0,49	0	neutral	0,92	neutral	0,24	deleterious	1	deleterious	0,79	low_impact	-1,72	medium_impact	0,13	medium_impact	1,35	0,17	0,8	56,58	8,8	N	0,38	N	0,87	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14968	14968	T	A	MI.8795	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	222	74	N	K	aaT/aaA	6,84	1	0,01	probably_damaging	0,99	neutral	0,29	neutral	4,59	neutral	-0,61	deleterious	-3,17	medium_impact	2,87	neutral	0,86	damaging	0,07	deleterious	3,82	23,4	0,32	0,5	neutral	0,32	disease	0,86	disease	0,61	disease	0,66	3	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,81	low_impact	-2,59	medium_impact	0,01	medium_impact	1,41	0,39	0,8	56,58	8,8	N	0,48	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14968	14968	T	G	MI.8796	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	222	74	N	K	aaT/aaG	6,84	1	0,01	probably_damaging	0,99	neutral	0,29	neutral	4,59	neutral	-0,61	deleterious	-3,17	medium_impact	2,87	neutral	0,86	damaging	0,07	deleterious	3,55	23,1	0,32	0,5	neutral	0,32	disease	0,86	disease	0,61	disease	0,66	3	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,81	low_impact	-2,59	medium_impact	0,01	medium_impact	1,41	0,39	0,8	56,58	8,8	N	0,47	N	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14969	14969	T	C	MI.8797	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	223	75	Y	H	Tat/Cat	-1,65	0	0	probably_damaging	1	neutral	0,55	neutral	4,44	deleterious	-3,63	deleterious	-3,45	medium_impact	2,37	neutral	0,94	neutral	0,62	deleterious	2,15	17,19	0,13	0,4	disease	0,67	disease	0,77	disease	0,57	neutral	0,35	3	deleterious	1	neutral	0,28	deleterious	1	deleterious	0,85	low_impact	-3,53	medium_impact	0,27	medium_impact	0,96	0,11	0,8	22,63	7,89	N	0,24	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14969	14969	T	G	MI.8798	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	223	75	Y	D	Tat/Gat	-1,65	0	0	probably_damaging	1	neutral	0,2	neutral	4,43	deleterious	-4,22	deleterious	-7,49	high_impact	4,85	neutral	0,9	neutral	0,36	deleterious	3,59	23,2	0,04	0,35	disease	0,58	disease	0,92	disease	0,8	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,1	high_impact	3,21	0,07	0,8	22,63	7,89	P	0,68	P	1	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14969	14969	T	A	MI.8799	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	223	75	Y	N	Tat/Aat	-1,65	0	0	probably_damaging	1	neutral	0,34	neutral	4,46	neutral	-2,37	deleterious	-6,65	medium_impact	2,36	neutral	0,91	neutral	0,46	deleterious	3,86	23,5	0,07	0,35	neutral	0,29	disease	0,88	disease	0,53	neutral	0,22	6	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,81	low_impact	-3,53	medium_impact	0,07	medium_impact	0,95	0,1	0,8	22,63	7,89	N	0,36	N	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8566	8566	A	T	MI.88	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	40	14	I	F	Atc/Ttc	-0,8	0	0,01	possibly_damaging	0,68	neutral	0,67	neutral	4,63	neutral	-1,5	neutral	-1,05	neutral_impact	-0,22	neutral	0,89	neutral	0,92	deleterious	1,93	15,79	0,53	0,65	disease	0,65	neutral	0,4	neutral	0,34	disease	0,62	2	neutral	0,62	deleterious	0,5	neutral	-3	deleterious	0,58	low_impact	-1,07	medium_impact	0,47	low_impact	-1,29	0,76	0,9	13,72	12,42	N	0,33	N	0,53	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8940	8940	C	A	MI.880	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	414	138	I	M	atC/atA	5,91	1	0	probably_damaging	1	neutral	0,5	neutral	4,19	neutral	-1,61	deleterious	-2,62	low_impact	1,66	neutral	0,79	neutral	0,57	deleterious	3,89	23,5	0,53	0,65	neutral	0,42	neutral	0,27	neutral	0,41	neutral	0,42	2	deleterious	0,99	neutral	0,25	neutral	-2	deleterious	0,7	low_impact	-3,6	medium_impact	0,29	medium_impact	0,33	0,83	0,9	44,69	8,06	P	0,49	N	0,75	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14970	14970	A	G	MI.8800	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	224	75	Y	C	tAt/tGt	3,63	0,98	0	probably_damaging	1	neutral	0,18	neutral	4,43	deleterious	-3,96	deleterious	-6,86	high_impact	4,22	neutral	0,92	neutral	0,32	deleterious	3,4	23	0,04	0,35	disease	0,8	disease	0,9	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,14	high_impact	2,64	0,04	0,8	22,63	7,89	P	0,55	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14970	14970	A	C	MI.8801	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	224	75	Y	S	tAt/tCt	3,63	0,98	0	probably_damaging	1	neutral	0,4	neutral	4,49	neutral	-1,93	deleterious	-6,71	medium_impact	3,39	neutral	0,93	neutral	0,48	deleterious	3,37	22,9	0,07	0,35	neutral	0,29	disease	0,89	disease	0,56	disease	0,62	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,83	low_impact	-3,53	medium_impact	0,13	medium_impact	1,88	0,12	0,8	22,63	7,89	N	0,51	P	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14970	14970	A	T	MI.8802	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	224	75	Y	F	tAt/tTt	3,63	0,98	0	probably_damaging	0,97	neutral	0,7	neutral	4,63	neutral	0,01	deleterious	-2,52	medium_impact	1,96	neutral	0,95	neutral	0,47	neutral	1,46	13,11	0,24	0,45	neutral	0,41	disease	0,78	neutral	0,45	neutral	0,16	7	neutral	0,96	neutral	0,37	deleterious	1	deleterious	0,83	low_impact	-2,14	medium_impact	0,42	medium_impact	0,59	0,28	0,8	22,63	7,89	N	0,38	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14972	14972	G	A	MI.8803	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	226	76	G	S	Ggc/Agc	-1,65	0	0	probably_damaging	1	neutral	0,4	neutral	3,14	deleterious	-6,14	deleterious	-5,09	high_impact	4,91	neutral	0,84	damaging	0,04	deleterious	4,15	23,8	0,05	0,35	disease	0,87	disease	0,84	disease	0,75	disease	0,63	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,13	high_impact	3,26	0,49	0,8	58,42	8,64	P	0,7	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14972	14972	G	C	MI.8804	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	226	76	G	R	Ggc/Cgc	-1,65	0	0	probably_damaging	1	neutral	0,35	neutral	3,1	deleterious	-7,18	deleterious	-6,79	high_impact	5,25	neutral	0,79	damaging	0,03	deleterious	3,92	23,5	0,03	0,35	disease	0,95	disease	0,88	disease	0,84	disease	0,66	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,93	low_impact	-3,53	medium_impact	0,08	high_impact	3,57	0,42	0,8	58,42	8,64	P	0,66	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14972	14972	G	T	MI.8805	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	226	76	G	C	Ggc/Tgc	-1,65	0	0	probably_damaging	1	neutral	0,17	neutral	3,09	deleterious	-8,67	deleterious	-7,64	high_impact	4,7	neutral	0,81	damaging	0,02	deleterious	4,07	23,7	0,03	0,35	disease	0,96	disease	0,89	disease	0,78	disease	0,64	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,92	low_impact	-3,53	medium_impact	-0,15	high_impact	3,07	0,2	0,8	58,42	8,64	P	0,57	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14973	14973	G	A	MI.8806	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	227	76	G	D	gGc/gAc	5	1	0	probably_damaging	1	neutral	0,2	neutral	3,1	deleterious	-7,66	deleterious	-5,94	high_impact	5,05	neutral	0,78	damaging	0,04	deleterious	3,7	23,3	0,03	0,35	disease	0,88	disease	0,89	disease	0,85	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,1	high_impact	3,39	0,13	0,8	58,42	8,64	P	0,73	P	1	polymorphism	1	0,2	.	.	.	.	.	.	COSM1138288	.	.	.	.	.	.	.	.
chrM	14973	14973	G	T	MI.8807	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	227	76	G	V	gGc/gTc	5	1	0	probably_damaging	1	neutral	0,5	neutral	3,11	deleterious	-7,24	deleterious	-7,64	high_impact	5,6	neutral	0,81	damaging	0,06	deleterious	3,68	23,3	0,02	0,35	disease	0,94	disease	0,89	disease	0,8	disease	0,63	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0,22	high_impact	3,89	0,12	0,8	58,42	8,64	P	0,7	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14973	14973	G	C	MI.8808	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	227	76	G	A	gGc/gCc	5	1	0	probably_damaging	1	neutral	0,5	neutral	3,15	deleterious	-5,67	deleterious	-5,09	high_impact	5,25	neutral	0,86	damaging	0,07	deleterious	2,89	21,8	0,05	0,35	disease	0,85	disease	0,76	disease	0,78	disease	0,68	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,22	high_impact	3,57	0,34	0,8	58,42	8,64	P	0,75	P	0,83	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14975	14975	T	C	MI.8809	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	229	77	W	R	Tga/Cga	-5,32	0	0	probably_damaging	1	neutral	0,35	neutral	4,35	neutral	-2,43	deleterious	-11,87	high_impact	4,54	neutral	0,78	damaging	0,06	deleterious	3,44	23	0,03	0,35	disease	0,9	disease	0,92	disease	0,85	disease	0,63	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0,08	high_impact	2,93	0,09	0,8	57,37	8,71	N	0,55	P	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8941	8941	C	A	MI.881	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	415	139	P	T	Ccc/Acc	-4,73	0	0	probably_damaging	1	deleterious	0,03	neutral	4,02	deleterious	-3,34	deleterious	-7	high_impact	4,2	neutral	0,66	neutral	0,39	deleterious	3,7	23,3	0,29	0,65	disease	0,78	disease	0,7	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,83	low_impact	-3,6	medium_impact	-0,56	high_impact	2,5	0,86	0,9	48,23	8,84	N	0,36	N	0,93	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14975	14975	T	G	MI.8810	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	229	77	W	G	Tga/Gga	-5,32	0	0	probably_damaging	1	neutral	0,35	neutral	4,33	neutral	-2,88	deleterious	-11,02	high_impact	5,03	neutral	0,83	damaging	0,1	deleterious	3,53	23,1	0,04	0,35	disease	0,91	disease	0,89	disease	0,83	disease	0,62	2	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,08	high_impact	3,37	0,07	0,8	57,37	8,71	P	0,68	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14976	14976	G	T	MI.8811	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	230	77	W	L	tGa/tTa	5,69	1	0	probably_damaging	1	neutral	0,66	neutral	4,44	neutral	-1	deleterious	-11,03	high_impact	5,23	neutral	0,85	damaging	0,07	deleterious	3,78	23,4	0,04	0,35	disease	0,66	disease	0,9	disease	0,82	disease	0,73	5	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,38	high_impact	3,56	0,09	0,8	57,37	8,71	P	0,7	P	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14976	14976	G	C	MI.8812	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	230	77	W	S	tGa/tCa	5,69	1	0	probably_damaging	1	neutral	0,4	neutral	4,4	neutral	-1,35	deleterious	-11,87	high_impact	4,25	neutral	0,85	damaging	0,09	deleterious	3,68	23,3	0,03	0,35	disease	0,85	disease	0,93	disease	0,82	disease	0,66	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0,13	high_impact	2,67	0,06	0,8	57,37	8,71	P	0,61	P	0,99	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14977	14977	A	C	MI.8813	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	231	77	W	C	tgA/tgC	9,13	1	0	probably_damaging	1	neutral	0,18	neutral	4,31	deleterious	-4,87	deleterious	-11,02	high_impact	5,23	neutral	0,83	damaging	0,05	deleterious	3,88	23,5	0,03	0,35	disease	0,93	disease	0,92	disease	0,85	disease	0,65	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,14	high_impact	3,56	0,09	0,8	57,37	8,71	P	0,65	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14977	14977	A	T	MI.8814	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	231	77	W	C	tgA/tgT	9,13	1	0	probably_damaging	1	neutral	0,18	neutral	4,31	deleterious	-4,87	deleterious	-11,02	high_impact	5,23	neutral	0,83	damaging	0,05	deleterious	4,03	23,6	0,03	0,35	disease	0,93	disease	0,92	disease	0,85	disease	0,65	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,14	high_impact	3,56	0,09	0,8	57,37	8,71	P	0,66	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14978	14978	A	G	MI.8815	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	232	78	I	V	Atc/Gtc	3,17	0,99	0	benign	0	neutral	0,53	neutral	4,7	neutral	0,07	neutral	-0,74	low_impact	0,82	neutral	0,99	neutral	0,97	deleterious	0,02	2,81	0,32	0,5	neutral	0,21	neutral	0,37	neutral	0,4	neutral	0,42	2	neutral	0,47	deleterious	0,77	neutral	-6	neutral	0,09	high_impact	2,07	medium_impact	0,25	medium_impact	-0,45	0,44	0,8	23,68	26,02	N	0,39	N	0,5	polymorphism	1	0,01	rs199997767	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14978	14978	A	T	MI.8816	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	232	78	I	F	Atc/Ttc	3,17	0,99	0	benign	0,33	neutral	0,77	neutral	4,66	neutral	0,07	neutral	-1,82	neutral_impact	0,73	neutral	0,97	neutral	0,6	deleterious	2,12	17	0,1	0,4	disease	0,68	disease	0,73	neutral	0,39	neutral	0,23	5	neutral	0,22	deleterious	0,72	neutral	-6	deleterious	0,44	medium_impact	-0,44	medium_impact	0,51	medium_impact	-0,53	0,67	0,85	23,68	26,02	N	0,33	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14978	14978	A	C	MI.8817	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	232	78	I	L	Atc/Ctc	3,17	0,99	0	benign	0,02	neutral	0,76	neutral	5,05	neutral	1,81	neutral	1,18	neutral_impact	-1,9	neutral	0,96	neutral	0,92	neutral	-0,83	0,04	0,2	0,45	neutral	0,16	neutral	0,11	neutral	0,27	neutral	0,21	6	neutral	0,19	deleterious	0,87	neutral	-6	neutral	0,09	medium_impact	0,85	medium_impact	0,49	low_impact	-2,92	0,75	0,85	23,68	26,02	N	0,43	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14979	14979	T	C	MI.8818	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	233	78	I	T	aTc/aCc	-1,42	0	0,11	possibly_damaging	0,84	neutral	0,4	neutral	4,58	neutral	-1,72	deleterious	-2,5	medium_impact	2,11	neutral	1	neutral	0,81	deleterious	2,27	17,94	0,06	0,35	disease	0,63	disease	0,58	disease	0,56	disease	0,58	2	neutral	0,84	neutral	0,28	NA	0	neutral	0,23	low_impact	-1,4	medium_impact	0,13	medium_impact	0,72	0,31	0,8	23,68	26,02	N	0,37	N	0,7	polymorphism	1	0,03	rs200786872	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14979	14979	T	A	MI.8819	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	233	78	I	N	aTc/aAc	-1,42	0	0,11	probably_damaging	0,98	neutral	0,37	neutral	4,54	deleterious	-3,39	deleterious	-4,23	medium_impact	3,36	neutral	0,93	neutral	0,51	deleterious	4,48	24,2	0,05	0,35	disease	0,86	disease	0,85	disease	0,59	disease	0,7	4	deleterious	0,98	neutral	0,2	deleterious	1	deleterious	0,8	low_impact	-2,31	medium_impact	0,1	medium_impact	1,86	0,33	0,8	23,68	26,02	N	0,38	N	0,82	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8941	8941	C	T	MI.882	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	415	139	P	S	Ccc/Tcc	-4,73	0	0	probably_damaging	1	neutral	0,08	neutral	4,05	deleterious	-3,77	deleterious	-7	medium_impact	3,23	damaging	0,57	neutral	0,52	deleterious	3,93	23,5	0,34	0,65	disease	0,67	disease	0,68	disease	0,72	disease	0,65	3	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	-0,31	medium_impact	1,67	0,42	0,9	48,23	8,84	N	0,33	N	0,82	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14979	14979	T	G	MI.8820	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	233	78	I	S	aTc/aGc	-1,42	0	0,11	probably_damaging	0,91	neutral	0,44	neutral	4,56	neutral	-2,13	deleterious	-3,38	medium_impact	3	neutral	0,94	neutral	0,49	deleterious	4,18	23,8	0,02	0,35	disease	0,75	disease	0,76	disease	0,6	disease	0,7	4	neutral	0,9	neutral	0,27	deleterious	1	deleterious	0,47	low_impact	-1,67	medium_impact	0,17	medium_impact	1,53	0,31	0,8	23,68	26,02	N	0,32	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14980	14980	C	A	MI.8821	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	234	78	I	M	atC/atA	4,54	0,66	0	benign	0,04	neutral	0,24	neutral	4,6	neutral	-0,87	neutral	-0,24	neutral_impact	0,31	neutral	0,96	neutral	0,74	deleterious	2,26	17,89	0,19	0,45	disease	0,64	neutral	0,44	neutral	0,35	disease	0,58	2	neutral	0,74	deleterious	0,6	neutral	-6	neutral	0,2	medium_impact	0,56	medium_impact	-0,05	medium_impact	-0,91	0,63	0,8	23,68	26,02	N	0,38	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14980	14980	C	G	MI.8822	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	234	78	I	M	atC/atG	4,54	0,66	0	benign	0,04	neutral	0,24	neutral	4,6	neutral	-0,87	neutral	-0,24	neutral_impact	0,31	neutral	0,96	neutral	0,74	neutral	1,76	14,73	0,19	0,45	disease	0,64	neutral	0,44	neutral	0,35	disease	0,58	2	neutral	0,74	deleterious	0,6	neutral	-6	neutral	0,2	medium_impact	0,56	medium_impact	-0,05	medium_impact	-0,91	0,63	0,8	23,68	26,02	N	0,38	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14981	14981	A	T	MI.8823	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	235	79	I	F	Atc/Ttc	-8,07	0	0	possibly_damaging	0,65	neutral	0,77	neutral	4,43	neutral	-2,08	deleterious	-3,05	medium_impact	2,94	neutral	0,95	neutral	0,43	deleterious	2,08	16,71	0,07	0,35	neutral	0,37	disease	0,85	neutral	0,48	disease	0,59	2	neutral	0,58	deleterious	0,56	NA	0	deleterious	0,69	medium_impact	-0,98	medium_impact	0,51	medium_impact	1,48	0,72	0,85	18,16	18,79	N	0,26	N	0,89	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14981	14981	A	C	MI.8824	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	235	79	I	L	Atc/Ctc	-8,07	0	0	benign	0,08	neutral	0,81	neutral	4,67	neutral	0,05	neutral	-1,22	low_impact	1,12	neutral	0,96	neutral	0,9	deleterious	0,67	8,61	0,23	0,45	neutral	0,15	disease	0,53	neutral	0,36	neutral	0,21	6	neutral	0,09	deleterious	0,87	neutral	-6	neutral	0,16	medium_impact	0,26	medium_impact	0,56	medium_impact	-0,18	0,73	0,85	18,16	18,79	N	0,27	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14981	14981	A	G	MI.8825	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	235	79	I	V	Atc/Gtc	-8,07	0	0	benign	0	neutral	0,51	neutral	4,54	neutral	-0,65	neutral	-0,73	medium_impact	2,66	neutral	0,98	neutral	0,65	neutral	1,1	11,22	0,44	0,55	neutral	0,37	disease	0,51	disease	0,56	neutral	0,31	4	neutral	0,49	deleterious	0,76	neutral	-3	neutral	0,16	high_impact	2,07	medium_impact	0,23	medium_impact	1,22	0,59	0,8	18,16	18,79	N	0,32	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14982	14982	T	C	MI.8826	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	236	79	I	T	aTc/aCc	3,63	0,99	0	probably_damaging	0,91	neutral	0,36	neutral	4,37	neutral	-2,78	deleterious	-3,71	high_impact	4,25	neutral	0,92	neutral	0,45	deleterious	3,29	22,8	0,04	0,35	disease	0,74	disease	0,82	disease	0,57	disease	0,62	2	neutral	0,92	neutral	0,23	deleterious	2	deleterious	0,75	low_impact	-1,67	medium_impact	0,09	high_impact	2,67	0,33	0,8	18,16	18,79	N	0,54	P	0,69	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14982	14982	T	G	MI.8827	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	236	79	I	S	aTc/aGc	3,63	0,99	0	probably_damaging	0,97	neutral	0,45	neutral	4,36	deleterious	-3,19	deleterious	-4,59	high_impact	4,8	neutral	0,94	neutral	0,43	deleterious	4,17	23,8	0,02	0,35	disease	0,83	disease	0,89	disease	0,61	disease	0,62	2	neutral	0,97	neutral	0,24	deleterious	2	deleterious	0,85	low_impact	-2,14	medium_impact	0,18	high_impact	3,17	0,32	0,8	18,16	18,79	P	0,71	P	0,89	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14982	14982	T	A	MI.8828	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	236	79	I	N	aTc/aAc	3,63	0,99	0	probably_damaging	0,99	neutral	0,36	neutral	4,34	deleterious	-4,23	deleterious	-5,44	high_impact	4,59	neutral	0,93	neutral	0,45	deleterious	4,36	24,1	0,06	0,35	disease	0,91	disease	0,89	disease	0,63	disease	0,63	3	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,87	low_impact	-2,59	medium_impact	0,09	high_impact	2,97	0,4	0,8	18,16	18,79	P	0,6	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14983	14983	C	A	MI.8829	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	237	79	I	M	atC/atA	5,69	1	0	possibly_damaging	0,81	neutral	0,22	neutral	4,41	neutral	-1,86	neutral	-1,91	medium_impact	2,27	neutral	0,95	neutral	0,39	deleterious	3,3	22,9	0,16	0,45	disease	0,58	disease	0,58	neutral	0,43	neutral	0,21	6	neutral	0,88	neutral	0,21	NA	0	deleterious	0,54	low_impact	-1,32	medium_impact	-0,08	medium_impact	0,87	0,76	0,85	18,16	18,79	P	0,55	P	0,81	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8941	8941	C	G	MI.883	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	415	139	P	A	Ccc/Gcc	-4,73	0	0	probably_damaging	1	neutral	0,08	neutral	4,06	neutral	-2,83	deleterious	-7	high_impact	4,2	neutral	0,63	neutral	0,47	deleterious	3,14	22,6	0,24	0,65	disease	0,7	disease	0,5	disease	0,73	disease	0,7	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,78	low_impact	-3,6	medium_impact	-0,31	high_impact	2,5	0,82	0,9	48,23	8,84	N	0,42	N	0,79	disease_causing	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14983	14983	C	G	MI.8830	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	237	79	I	M	atC/atG	5,69	1	0	possibly_damaging	0,81	neutral	0,22	neutral	4,41	neutral	-1,86	neutral	-1,91	medium_impact	2,27	neutral	0,95	neutral	0,39	deleterious	2,89	21,8	0,16	0,45	disease	0,58	disease	0,58	neutral	0,43	neutral	0,21	6	neutral	0,88	neutral	0,21	NA	0	deleterious	0,54	low_impact	-1,32	medium_impact	-0,08	medium_impact	0,87	0,76	0,85	18,16	18,79	P	0,55	P	0,81	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14984	14984	C	A	MI.8831	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	238	80	R	S	Cgc/Agc	-3,71	0	0	probably_damaging	0,99	neutral	0,4	neutral	3,87	deleterious	-4,63	deleterious	-5,04	high_impact	5,53	neutral	0,8	damaging	0,06	deleterious	2,92	21,9	0,03	0,35	disease	0,87	disease	0,91	disease	0,74	disease	0,62	2	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,91	low_impact	-2,59	medium_impact	0,13	high_impact	3,83	0,2	0,8	55,26	8,41	P	0,7	P	0,74	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14984	14984	C	G	MI.8832	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	238	80	R	G	Cgc/Ggc	-3,71	0	0	probably_damaging	0,99	neutral	0,33	neutral	3,85	deleterious	-5,71	deleterious	-5,89	high_impact	5,18	neutral	0,86	damaging	0,08	deleterious	2,46	19,19	0,03	0,35	disease	0,9	disease	0,87	disease	0,76	disease	0,6	2	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-2,59	medium_impact	0,06	high_impact	3,51	0,2	0,8	55,26	8,41	P	0,7	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14984	14984	C	T	MI.8833	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	238	80	R	C	Cgc/Tgc	-3,71	0	0	probably_damaging	1	neutral	0,18	neutral	3,83	deleterious	-6,93	deleterious	-6,74	high_impact	5,53	neutral	0,86	damaging	0,04	deleterious	4,84	24,8	0,05	0,35	disease	0,97	disease	0,92	disease	0,78	disease	0,6	2	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,14	high_impact	3,83	0,49	0,8	55,26	8,41	P	0,65	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14985	14985	G	C	MI.8834	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	239	80	R	P	cGc/cCc	2,71	0,98	0	probably_damaging	1	neutral	0,2	neutral	3,84	deleterious	-6,24	deleterious	-5,88	high_impact	4,38	neutral	0,86	damaging	0,04	deleterious	3,88	23,5	0,02	0,35	disease	0,93	disease	0,92	disease	0,85	disease	0,63	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,92	low_impact	-3,53	medium_impact	-0,1	high_impact	2,78	0,14	0,8	55,26	8,41	P	0,59	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14985	14985	G	T	MI.8835	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	239	80	R	L	cGc/cTc	2,71	0,98	0	probably_damaging	0,98	neutral	0,65	neutral	3,94	neutral	-2,91	deleterious	-5,88	high_impact	4,98	neutral	0,87	damaging	0,06	deleterious	2,48	19,36	0,03	0,35	disease	0,88	disease	0,95	disease	0,74	disease	0,65	3	deleterious	0,98	neutral	0,34	deleterious	2	deleterious	0,91	low_impact	-2,31	medium_impact	0,37	high_impact	3,33	0,09	0,8	55,26	8,41	P	0,66	P	1	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14985	14985	G	A	MI.8836	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	239	80	R	H	cGc/cAc	2,71	0,98	0	probably_damaging	1	neutral	0,54	neutral	3,85	deleterious	-5,21	deleterious	-4,16	medium_impact	3,5	neutral	0,82	damaging	0,06	deleterious	4,02	23,6	0,08	0,35	disease	0,9	disease	0,88	disease	0,74	disease	0,61	2	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,9	low_impact	-3,53	medium_impact	0,26	medium_impact	1,98	0,58	0,8	55,26	8,41	N	0,48	N	1	disease_causing_automatic	0	0,08	rs207459995	Pathogenic	Familial_colorectal_cancer	RCV000010314.2	MedGen	colorectal tumor	.	.	0,3	.	.	.	.	.	.
chrM	14987	14987	T	A	MI.8837	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	241	81	Y	N	Tac/Aac	-13,35	0	0	probably_damaging	0,95	neutral	0,31	neutral	4,68	neutral	-0,62	neutral	3,53	neutral_impact	-0,55	neutral	0,88	damaging	0,15	neutral	1,24	11,97	0,09	0,35	neutral	0,48	neutral	0,29	neutral	0,37	neutral	0,4	2	neutral	0,95	neutral	0,18	neutral	-2	deleterious	0,74	low_impact	-1,92	medium_impact	0,03	low_impact	-1,69	0,4	0,8	18,68	20,01	N	0,35	N	0,53	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14987	14987	T	C	MI.8838	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	241	81	Y	H	Tac/Cac	-13,35	0	0	benign	0,04	neutral	0,54	neutral	4,6	neutral	-1,16	neutral	1,05	medium_impact	3,4	neutral	0,9	neutral	0,51	deleterious	2,16	17,22	0,13	0,4	disease	0,74	disease	0,84	disease	0,55	disease	0,66	3	neutral	0,42	deleterious	0,75	neutral	-3	neutral	0,34	medium_impact	0,56	medium_impact	0,26	medium_impact	1,89	0,37	0,8	18,68	20,01	N	0,24	N	0,2	polymorphism	1	0,07	.	.	.	.	.	.	COSM1138290	.	.	.	.	.	.	.	.
chrM	14987	14987	T	G	MI.8839	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	241	81	Y	D	Tac/Gac	-13,35	0	0	probably_damaging	0,96	neutral	0,2	neutral	4,59	neutral	-1,19	neutral	0,22	high_impact	3,96	neutral	0,83	damaging	0,08	deleterious	2,07	16,68	0,07	0,35	disease	0,7	disease	0,94	disease	0,65	disease	0,76	5	neutral	0,97	neutral	0,12	deleterious	2	deleterious	0,88	low_impact	-2,02	medium_impact	-0,1	high_impact	2,4	0,24	0,8	18,68	20,01	N	0,34	N	0,96	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8942	8942	C	G	MI.884	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	416	139	P	R	cCc/cGc	4,52	0,99	0	probably_damaging	1	deleterious	0,01	neutral	4,01	deleterious	-4,74	deleterious	-7,92	high_impact	4,54	neutral	0,64	neutral	0,4	deleterious	3,63	23,2	0,21	0,65	disease	0,8	disease	0,81	disease	0,82	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-3,6	medium_impact	-0,84	high_impact	2,79	0,78	0,9	48,23	8,84	P	0,55	P	0,65	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14988	14988	A	T	MI.8840	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	242	81	Y	F	tAc/tTc	2,71	0,98	0	benign	0,4	neutral	0,71	neutral	4,58	neutral	-2,24	neutral	-1,31	medium_impact	3,1	neutral	0,87	damaging	0,11	deleterious	2,13	17,08	0,18	0,45	disease	0,62	disease	0,89	neutral	0,45	disease	0,64	3	neutral	0,3	deleterious	0,66	neutral	-3	deleterious	0,54	medium_impact	-0,57	medium_impact	0,43	medium_impact	1,62	0,52	0,8	18,68	20,01	N	0,34	N	0,56	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14988	14988	A	C	MI.8841	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	242	81	Y	S	tAc/tCc	2,71	0,98	0	probably_damaging	0,96	neutral	0,4	neutral	4,69	neutral	0,2	neutral	0,58	low_impact	0,96	neutral	0,91	damaging	0,12	deleterious	2,59	20,1	0,07	0,35	disease	0,5	disease	0,84	neutral	0,46	neutral	0,16	7	neutral	0,96	neutral	0,22	neutral	-2	deleterious	0,73	low_impact	-2,02	medium_impact	0,13	medium_impact	-0,32	0,41	0,8	18,68	20,01	N	0,44	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14988	14988	A	G	MI.8842	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	242	81	Y	C	tAc/tGc	2,71	0,98	0	probably_damaging	0,96	neutral	0,18	neutral	4,54	deleterious	-4,75	neutral	-2,13	high_impact	3,61	neutral	0,87	damaging	0,06	deleterious	3,88	23,5	0,05	0,35	disease	0,78	disease	0,94	disease	0,6	disease	0,73	5	neutral	0,98	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-2,02	medium_impact	-0,14	high_impact	2,08	0,24	0,8	18,68	20,01	N	0,43	N	0,93	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14990	14990	C	A	MI.8843	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	244	82	L	I	Ctt/Att	-4,17	0	0,01	probably_damaging	0,98	neutral	0,44	neutral	4,62	neutral	-0,2	neutral	-0,77	neutral_impact	0,56	neutral	0,93	neutral	0,91	neutral	1,25	12,01	0,18	0,45	neutral	0,35	disease	0,51	neutral	0,31	neutral	0,25	5	deleterious	0,98	neutral	0,23	neutral	-2	deleterious	0,71	low_impact	-2,31	medium_impact	0,17	medium_impact	-0,69	0,41	0,8	10,26	19,6	N	0,34	N	0,45	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14990	14990	C	G	MI.8844	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	244	82	L	V	Ctt/Gtt	-4,17	0	0,01	probably_damaging	0,96	neutral	0,48	neutral	4,56	neutral	-0,64	neutral	-1,33	medium_impact	2,82	neutral	0,91	neutral	0,71	deleterious	0,48	7,31	0,17	0,45	disease	0,51	disease	0,74	neutral	0,39	neutral	0,2	6	neutral	0,96	neutral	0,26	deleterious	1	deleterious	0,74	low_impact	-2,02	medium_impact	0,2	medium_impact	1,37	0,5	0,8	10,26	19,6	N	0,27	N	0,42	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14990	14990	C	T	MI.8845	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	244	82	L	F	Ctt/Ttt	-4,17	0	0,01	probably_damaging	1	neutral	0,75	neutral	4,45	neutral	-2,31	deleterious	-2,54	medium_impact	2,95	neutral	0,77	neutral	0,57	deleterious	3,6	23,2	0,08	0,35	neutral	0,44	disease	0,86	disease	0,52	disease	0,62	2	deleterious	0,99	neutral	0,38	deleterious	1	deleterious	0,77	low_impact	-3,53	medium_impact	0,48	medium_impact	1,49	0,51	0,8	10,26	19,6	N	0,18	N	0,53	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14991	14991	T	G	MI.8846	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	245	82	L	R	cTt/cGt	-1,42	0	0	probably_damaging	1	neutral	0,37	neutral	4,4	deleterious	-3,77	deleterious	-4,13	high_impact	4,68	neutral	0,84	neutral	0,45	deleterious	4	23,6	0,02	0,35	disease	0,86	disease	0,94	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,1	high_impact	3,06	0,2	0,8	10,26	19,6	N	0,56	P	0,9	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14991	14991	T	A	MI.8847	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	245	82	L	H	cTt/cAt	-1,42	0	0	probably_damaging	1	neutral	0,57	neutral	4,4	deleterious	-4,31	deleterious	-4,81	high_impact	4,68	neutral	0,82	neutral	0,46	deleterious	3,98	23,6	0,03	0,35	disease	0,9	disease	0,86	disease	0,67	disease	0,64	3	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,29	high_impact	3,06	0,25	0,8	10,26	19,6	N	0,52	P	0,88	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14991	14991	T	C	MI.8848	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	245	82	L	P	cTt/cCt	-1,42	0	0	probably_damaging	1	neutral	0,2	neutral	4,4	deleterious	-4,35	deleterious	-4,79	high_impact	4,68	neutral	0,83	neutral	0,34	deleterious	3,73	23,3	0,02	0,35	disease	0,89	disease	0,93	disease	0,71	disease	0,67	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,1	high_impact	3,06	0,23	0,8	10,26	19,6	N	0,56	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	COSM1155583	.	.	.	.	.	.	.	.
chrM	14993	14993	C	G	MI.8849	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	247	83	H	D	Cac/Gac	-4,63	0	0	probably_damaging	0,99	neutral	0,2	neutral	2,78	deleterious	-10,97	deleterious	-7,62	high_impact	5,06	neutral	0,92	damaging	0,11	deleterious	2,23	17,74	0,03	0,35	disease	0,79	disease	0,92	disease	0,87	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-2,59	medium_impact	-0,1	high_impact	3,4	0,31	0,8	58,16	8,67	P	0,59	P	0,98	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8942	8942	C	A	MI.885	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	416	139	P	H	cCc/cAc	4,52	0,99	0	probably_damaging	1	deleterious	0,01	neutral	3,94	deleterious	-4,81	deleterious	-7,92	high_impact	4,54	damaging	0,6	neutral	0,32	deleterious	4,08	23,7	0,24	0,65	disease	0,9	disease	0,76	disease	0,81	disease	0,81	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-3,6	medium_impact	-0,84	high_impact	2,79	0,73	0,9	48,23	8,84	P	0,57	P	0,64	disease_causing	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14993	14993	C	T	MI.8850	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	247	83	H	Y	Cac/Tac	-4,63	0	0	probably_damaging	0,98	neutral	1	neutral	2,79	deleterious	-9,56	deleterious	-5,08	high_impact	5,61	neutral	0,94	damaging	0,13	deleterious	1,92	15,69	0,06	0,35	disease	0,81	disease	0,94	disease	0,81	disease	0,74	5	deleterious	0,98	deleterious	0,51	deleterious	2	deleterious	0,89	low_impact	-2,31	high_impact	1,85	high_impact	3,9	0,4	0,8	58,16	8,67	P	0,67	P	1	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14993	14993	C	A	MI.8851	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	247	83	H	N	Cac/Aac	-4,63	0	0	probably_damaging	0,99	neutral	0,34	neutral	2,78	deleterious	-9,41	deleterious	-5,93	high_impact	5,26	neutral	0,93	damaging	0,13	deleterious	2,1	16,88	0,12	0,4	disease	0,83	disease	0,92	disease	0,81	disease	0,67	3	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-2,59	medium_impact	0,07	high_impact	3,58	0,43	0,8	58,16	8,67	P	0,69	P	0,97	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14994	14994	A	C	MI.8852	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	248	83	H	P	cAc/cCc	7,07	1	0	probably_damaging	1	neutral	0,2	neutral	2,77	deleterious	-11,53	deleterious	-8,47	high_impact	4,8	neutral	0,95	damaging	0,08	neutral	1,62	13,94	0,02	0,35	disease	0,91	disease	0,94	disease	0,88	disease	0,65	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,1	high_impact	3,17	0,33	0,8	58,16	8,67	P	0,63	P	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14994	14994	A	G	MI.8853	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	248	83	H	R	cAc/cGc	7,07	1	0	probably_damaging	0,98	neutral	0,36	neutral	2,79	deleterious	-10,6	deleterious	-6,77	high_impact	5,61	neutral	0,94	damaging	0,09	neutral	1,21	11,78	0,04	0,35	disease	0,78	disease	0,94	disease	0,85	disease	0,79	6	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,9	low_impact	-2,31	medium_impact	0,09	high_impact	3,9	0,51	0,8	58,16	8,67	P	0,67	P	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14994	14994	A	T	MI.8854	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	248	83	H	L	cAc/cTc	7,07	1	0	probably_damaging	0,98	neutral	0,79	neutral	2,77	deleterious	-11,74	deleterious	-9,31	high_impact	5,61	neutral	0,95	damaging	0,11	deleterious	1,98	16,11	0,03	0,35	disease	0,85	disease	0,96	disease	0,83	disease	0,69	4	deleterious	0,98	neutral	0,41	deleterious	2	deleterious	0,89	low_impact	-2,31	medium_impact	0,53	high_impact	3,9	0,32	0,8	58,16	8,67	P	0,68	P	0,92	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14995	14995	C	A	MI.8855	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	249	83	H	Q	caC/caA	8,44	1	0	probably_damaging	0,99	neutral	0,28	neutral	2,78	deleterious	-9,82	deleterious	-6,77	high_impact	4,92	neutral	0,93	damaging	0,11	deleterious	2,13	17,05	0,07	0,35	disease	0,81	disease	0,89	disease	0,82	disease	0,69	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-2,59	medium_impact	0	high_impact	3,27	0,42	0,8	58,16	8,67	P	0,72	P	0,94	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14995	14995	C	G	MI.8856	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	249	83	H	Q	caC/caG	8,44	1	0	probably_damaging	0,99	neutral	0,28	neutral	2,78	deleterious	-9,82	deleterious	-6,77	high_impact	4,92	neutral	0,93	damaging	0,11	neutral	1,79	14,92	0,07	0,35	disease	0,81	disease	0,89	disease	0,82	disease	0,69	4	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-2,59	medium_impact	0	high_impact	3,27	0,42	0,8	58,16	8,67	P	0,71	P	0,94	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14996	14996	G	T	MI.8857	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	250	84	A	S	Gcc/Tcc	-6,24	0	0,01	benign	0,13	neutral	0,4	neutral	4,55	neutral	-0,38	neutral	-2,31	medium_impact	2,98	neutral	0,83	neutral	0,47	deleterious	1,88	15,47	0,13	0,4	neutral	0,43	disease	0,88	disease	0,54	disease	0,65	3	neutral	0,53	deleterious	0,64	neutral	-3	neutral	0,33	medium_impact	0,04	medium_impact	0,13	medium_impact	1,51	0,46	0,8	51,32	8,13	N	0,28	N	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14996	14996	G	A	MI.8858	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	250	84	A	T	Gcc/Acc	-6,24	0	0,01	benign	0	neutral	0,39	neutral	4,47	neutral	-2,45	deleterious	-2,9	high_impact	3,87	neutral	0,84	neutral	0,48	deleterious	2,52	19,61	0,09	0,35	disease	0,66	disease	0,89	disease	0,57	disease	0,53	1	neutral	0,6	deleterious	0,7	neutral	-2	neutral	0,32	high_impact	2,07	medium_impact	0,12	high_impact	2,32	0,71	0,85	51,32	8,13	N	0,34	N	0,79	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14996	14996	G	C	MI.8859	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	250	84	A	P	Gcc/Ccc	-6,24	0	0,01	possibly_damaging	0,44	neutral	0,2	neutral	4,42	deleterious	-3,86	deleterious	-4,02	high_impact	4,89	neutral	0,84	neutral	0,29	deleterious	3,42	23	0,03	0,35	disease	0,8	disease	0,91	disease	0,76	disease	0,68	4	neutral	0,77	neutral	0,38	deleterious	1	deleterious	0,73	medium_impact	-0,63	medium_impact	-0,1	high_impact	3,25	0,48	0,8	51,32	8,13	P	0,67	P	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8942	8942	C	T	MI.886	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	416	139	P	L	cCc/cTc	4,52	0,99	0	probably_damaging	1	neutral	0,24	neutral	3,95	neutral	-1,94	deleterious	-8,8	medium_impact	3,35	damaging	0,56	neutral	0,41	deleterious	4,45	24,2	0,3	0,65	disease	0,66	disease	0,73	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,81	low_impact	-3,6	medium_impact	0,01	medium_impact	1,77	0,8	0,9	48,23	8,84	N	0,49	N	0,95	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14997	14997	C	G	MI.8860	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	251	84	A	G	gCc/gGc	4,08	1	0	benign	0,05	neutral	0,33	neutral	4,45	neutral	-0,81	deleterious	-3,27	high_impact	4,75	neutral	0,82	neutral	0,51	deleterious	2,06	16,57	0,13	0,4	disease	0,72	disease	0,86	disease	0,64	disease	0,68	4	neutral	0,64	deleterious	0,64	neutral	-2	neutral	0,35	medium_impact	0,46	medium_impact	0,06	high_impact	3,12	0,61	0,8	51,32	8,13	P	0,63	P	0,83	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14997	14997	C	A	MI.8861	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	251	84	A	D	gCc/gAc	4,08	1	0	benign	0,36	neutral	0,21	neutral	4,46	neutral	-2,76	deleterious	-4,8	high_impact	5,44	neutral	0,8	neutral	0,39	deleterious	4,11	23,7	0,02	0,35	disease	0,84	disease	0,94	disease	0,74	disease	0,67	3	neutral	0,75	neutral	0,43	neutral	-2	deleterious	0,72	medium_impact	-0,5	medium_impact	-0,09	high_impact	3,75	0,23	0,8	51,32	8,13	P	0,65	P	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14997	14997	C	T	MI.8862	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	251	84	A	V	gCc/gTc	4,08	1	0	benign	0,08	neutral	0,5	neutral	4,45	deleterious	-3,23	deleterious	-3,17	high_impact	3,85	neutral	0,84	neutral	0,5	deleterious	2,7	20,8	0,05	0,35	disease	0,71	disease	0,92	disease	0,64	disease	0,69	4	neutral	0,43	deleterious	0,71	neutral	-2	deleterious	0,56	medium_impact	0,26	medium_impact	0,22	high_impact	2,3	0,72	0,85	51,32	8,13	N	0,52	P	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14999	14999	A	T	MI.8863	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	253	85	N	Y	Aat/Tat	-9,68	0	0	probably_damaging	1	neutral	1	neutral	4,58	neutral	0,07	deleterious	-6,82	high_impact	5,48	neutral	0,78	neutral	0,33	deleterious	3,64	23,2	0,06	0,35	disease	0,92	disease	0,95	disease	0,72	disease	0,65	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,9	low_impact	-3,53	high_impact	1,85	high_impact	3,78	0,26	0,8	58,42	8,75	P	0,58	P	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14999	14999	A	C	MI.8864	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	253	85	N	H	Aat/Cat	-9,68	0	0	probably_damaging	1	neutral	0,55	neutral	4,5	neutral	-2,61	deleterious	-4,26	high_impact	5,13	neutral	0,82	damaging	0,21	deleterious	2,95	22	0,2	0,45	disease	0,9	disease	0,9	disease	0,76	disease	0,67	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,27	high_impact	3,46	0,28	0,8	58,42	8,75	P	0,7	P	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	14999	14999	A	G	MI.8865	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	253	85	N	D	Aat/Gat	-9,68	0	0	probably_damaging	0,99	neutral	0,2	neutral	4,5	neutral	-2,6	deleterious	-4,26	high_impact	3,98	neutral	0,79	neutral	0,36	deleterious	3,32	22,9	0,29	0,45	disease	0,71	disease	0,88	disease	0,72	disease	0,72	4	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-2,59	medium_impact	-0,1	high_impact	2,42	0,28	0,8	58,42	8,75	N	0,34	N	0,96	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15000	15000	A	C	MI.8866	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	254	85	N	T	aAt/aCt	6,84	1	0	probably_damaging	1	neutral	0,39	neutral	4,6	neutral	0,15	deleterious	-5,11	medium_impact	3,4	neutral	0,83	neutral	0,4	deleterious	3,18	22,7	0,16	0,45	disease	0,57	disease	0,9	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,85	low_impact	-3,53	medium_impact	0,12	medium_impact	1,89	0,36	0,8	58,42	8,75	N	0,53	P	0,94	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15000	15000	A	G	MI.8867	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	254	85	N	S	aAt/aGt	6,84	1	0	probably_damaging	0,98	neutral	0,4	neutral	4,53	neutral	-1,3	deleterious	-4,25	high_impact	3,94	neutral	0,83	neutral	0,4	neutral	1,36	12,56	0,24	0,45	disease	0,68	disease	0,88	disease	0,71	disease	0,73	5	neutral	0,98	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-2,31	medium_impact	0,13	high_impact	2,38	0,32	0,8	58,42	8,75	P	0,62	P	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15000	15000	A	T	MI.8868	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	254	85	N	I	aAt/aTt	6,84	1	0	probably_damaging	1	neutral	0,4	neutral	4,56	neutral	-0,26	deleterious	-7,67	high_impact	3,87	neutral	0,84	neutral	0,41	deleterious	3,94	23,5	0,06	0,35	disease	0,9	disease	0,97	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,13	high_impact	2,32	0,2	0,8	58,42	8,75	P	0,61	P	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15001	15001	T	G	MI.8869	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	255	85	N	K	aaT/aaG	8,44	1	0,01	probably_damaging	1	neutral	0,29	neutral	4,51	neutral	-1,8	deleterious	-5,11	high_impact	4,5	neutral	0,83	damaging	0,28	deleterious	3,9	23,5	0,18	0,45	disease	0,77	disease	0,93	disease	0,77	disease	0,77	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,01	high_impact	2,89	0,54	0,8	58,42	8,75	P	0,69	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8944	8944	A	G	MI.887	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	418	140	M	V	Ata/Gta	-15,14	0	0	possibly_damaging	0,87	neutral	0,44	neutral	4,55	neutral	1,84	neutral	-1,36	neutral_impact	-0,52	neutral	0,9	neutral	0,65	deleterious	0,55	7,79	0,39	0,65	neutral	0,41	neutral	0,21	neutral	0,34	neutral	0,36	3	neutral	0,87	neutral	0,29	neutral	-3	deleterious	0,57	low_impact	-1,54	medium_impact	0,23	low_impact	-1,54	0,66	0,9	44,25	8,21	N	0,37	N	0,95	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15001	15001	T	A	MI.8870	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	255	85	N	K	aaT/aaA	8,44	1	0,01	probably_damaging	1	neutral	0,29	neutral	4,51	neutral	-1,8	deleterious	-5,11	high_impact	4,5	neutral	0,83	damaging	0,28	deleterious	4,15	23,8	0,18	0,45	disease	0,77	disease	0,93	disease	0,77	disease	0,77	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,01	high_impact	2,89	0,54	0,8	58,42	8,75	P	0,69	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15002	15002	G	T	MI.8871	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	256	86	G	C	Ggc/Tgc	-2,8	0	0	probably_damaging	0,96	neutral	0,18	neutral	4,15	deleterious	-3,77	deleterious	-7,47	high_impact	5,03	neutral	0,79	damaging	0,23	deleterious	4,04	23,7	0,02	0,35	disease	0,91	disease	0,94	disease	0,71	disease	0,63	3	neutral	0,97	neutral	0,11	deleterious	2	deleterious	0,87	low_impact	-2,02	medium_impact	-0,14	high_impact	3,37	0,26	0,8	58,16	8,68	P	0,61	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15002	15002	G	C	MI.8872	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	256	86	G	R	Ggc/Cgc	-2,8	0	0	probably_damaging	0,93	neutral	0,35	neutral	4,17	deleterious	-3,21	deleterious	-6,64	high_impact	5,58	neutral	0,79	damaging	0,24	deleterious	3,87	23,5	0,02	0,35	disease	0,91	disease	0,94	disease	0,8	disease	0,66	3	neutral	0,93	neutral	0,21	deleterious	2	deleterious	0,9	low_impact	-1,78	medium_impact	0,08	high_impact	3,87	0,56	0,8	58,16	8,68	P	0,67	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15002	15002	G	A	MI.8873	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	256	86	G	S	Ggc/Agc	-2,8	0	0	benign	0,11	neutral	0,4	neutral	4,25	neutral	-2,38	deleterious	-4,82	high_impact	4,29	neutral	0,63	neutral	0,35	deleterious	4,13	23,8	0,04	0,35	disease	0,69	disease	0,87	disease	0,66	disease	0,69	4	neutral	0,54	deleterious	0,65	neutral	-2	neutral	0,43	medium_impact	0,12	medium_impact	0,13	high_impact	2,7	0,55	0,8	58,16	8,68	N	0,37	N	1	polymorphism	1	0,04	rs370448948	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15003	15003	G	A	MI.8874	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	257	86	G	D	gGc/gAc	5,92	1	0	possibly_damaging	0,72	neutral	0,2	neutral	4,16	deleterious	-4,12	deleterious	-5,79	high_impact	5,58	neutral	0,72	neutral	0,3	deleterious	3,7	23,3	0,02	0,35	disease	0,88	disease	0,92	disease	0,8	disease	0,64	3	neutral	0,85	neutral	0,24	deleterious	1	deleterious	0,84	low_impact	-1,11	medium_impact	-0,1	high_impact	3,87	0,15	0,8	58,16	8,68	P	0,76	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15003	15003	G	C	MI.8875	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	257	86	G	A	gGc/gCc	5,92	1	0	benign	0,21	neutral	0,51	neutral	4,41	neutral	-1,68	deleterious	-4,91	high_impact	5,23	neutral	0,8	neutral	0,43	deleterious	2,87	21,7	0,04	0,35	disease	0,65	disease	0,81	disease	0,69	disease	0,67	3	neutral	0,39	deleterious	0,65	neutral	-2	deleterious	0,61	medium_impact	-0,19	medium_impact	0,23	high_impact	3,56	0,47	0,8	58,16	8,68	P	0,65	P	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15003	15003	G	T	MI.8876	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	257	86	G	V	gGc/gTc	5,92	1	0	probably_damaging	0,93	neutral	0,5	neutral	4,21	neutral	-0,83	deleterious	-7,5	high_impact	4,68	neutral	0,79	neutral	0,37	deleterious	3,7	23,3	0,02	0,35	disease	0,85	disease	0,93	disease	0,72	disease	0,63	3	neutral	0,92	neutral	0,29	deleterious	2	deleterious	0,86	low_impact	-1,78	medium_impact	0,22	high_impact	3,06	0,17	0,8	58,16	8,68	P	0,61	P	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15005	15005	G	T	MI.8877	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	259	87	A	S	Gcc/Tcc	-6,47	0	0	probably_damaging	0,99	neutral	0,44	neutral	3,75	deleterious	-4	deleterious	-2,55	high_impact	4,26	neutral	0,88	damaging	0,08	deleterious	2,08	16,72	0,13	0,4	disease	0,78	disease	0,88	disease	0,68	disease	0,68	4	deleterious	0,99	neutral	0,23	deleterious	2	deleterious	0,86	low_impact	-2,59	medium_impact	0,17	high_impact	2,67	0,39	0,8	57,89	8,66	N	0,39	N	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15005	15005	G	A	MI.8878	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	259	87	A	T	Gcc/Acc	-6,47	0	0	probably_damaging	0,99	neutral	0,38	neutral	3,7	deleterious	-5,4	deleterious	-3,37	high_impact	4,68	neutral	0,88	damaging	0,08	deleterious	3,74	23,3	0,08	0,35	disease	0,83	disease	0,89	disease	0,72	disease	0,65	3	deleterious	0,99	neutral	0,2	deleterious	2	deleterious	0,87	low_impact	-2,59	medium_impact	0,11	high_impact	3,06	0,59	0,8	57,89	8,66	N	0,58	P	0,79	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15005	15005	G	C	MI.8879	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	259	87	A	P	Gcc/Ccc	-6,47	0	0	probably_damaging	1	neutral	0,2	neutral	3,66	deleterious	-7,12	deleterious	-4,28	high_impact	5,58	neutral	0,92	damaging	0,05	deleterious	3,58	23,2	0,03	0,35	disease	0,91	disease	0,92	disease	0,82	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,1	high_impact	3,87	0,42	0,8	57,89	8,66	P	0,72	P	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8944	8944	A	T	MI.888	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	418	140	M	L	Ata/Tta	-15,14	0	0	possibly_damaging	0,81	neutral	0,29	neutral	4,57	neutral	1,99	neutral	-1,45	neutral_impact	-0,2	neutral	0,87	neutral	0,64	deleterious	2,32	18,31	0,37	0,65	neutral	0,29	neutral	0,34	neutral	0,38	neutral	0,44	1	neutral	0,85	neutral	0,24	neutral	-3	deleterious	0,5	low_impact	-1,35	medium_impact	0,07	low_impact	-1,27	0,59	0,9	44,25	8,21	N	0,38	N	0,93	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15006	15006	C	G	MI.8880	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	260	87	A	G	gCc/gGc	7,07	1	0	probably_damaging	0,98	neutral	0,42	neutral	3,68	deleterious	-5,79	deleterious	-3,42	high_impact	4,54	neutral	0,87	damaging	0,08	deleterious	2,16	17,27	0,13	0,4	disease	0,83	disease	0,87	disease	0,66	disease	0,57	1	neutral	0,98	neutral	0,22	deleterious	2	deleterious	0,84	low_impact	-2,31	medium_impact	0,15	high_impact	2,93	0,6	0,8	57,89	8,66	P	0,57	P	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15006	15006	C	T	MI.8881	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	260	87	A	V	gCc/gTc	7,07	1	0	probably_damaging	0,99	neutral	0,51	neutral	3,72	deleterious	-5,64	deleterious	-3,42	high_impact	4,11	neutral	0,84	damaging	0,08	deleterious	2,86	21,7	0,07	0,35	disease	0,88	disease	0,92	disease	0,72	disease	0,62	2	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-2,59	medium_impact	0,23	high_impact	2,54	0,61	0,8	57,89	8,66	P	0,61	P	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15006	15006	C	A	MI.8882	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	260	87	A	D	gCc/gAc	7,07	1	0	probably_damaging	1	neutral	0,2	neutral	3,67	deleterious	-6,99	deleterious	-5,12	high_impact	5,24	neutral	0,81	damaging	0,06	deleterious	4,29	24	0,03	0,35	disease	0,93	disease	0,95	disease	0,81	disease	0,63	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,1	high_impact	3,56	0,26	0,8	57,89	8,66	P	0,76	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15008	15008	T	G	MI.8883	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	262	88	S	A	Tca/Gca	-6,93	0	0	probably_damaging	0,99	neutral	0,64	neutral	3,05	neutral	-1,42	deleterious	-2,57	high_impact	4,87	neutral	0,88	damaging	0,14	deleterious	3,27	22,8	0,16	0,45	disease	0,65	disease	0,73	disease	0,66	disease	0,65	3	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,8	low_impact	-2,59	medium_impact	0,36	high_impact	3,23	0,52	0,8	57,63	8,68	P	0,6	P	0,46	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15008	15008	T	A	MI.8884	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	262	88	S	T	Tca/Aca	-6,93	0	0	probably_damaging	0,99	neutral	0,39	neutral	3,04	neutral	-1,8	deleterious	-2,53	high_impact	4,07	neutral	0,86	damaging	0,1	deleterious	2,09	16,78	0,17	0,45	disease	0,75	disease	0,81	disease	0,73	disease	0,68	4	deleterious	0,99	neutral	0,2	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	0,12	high_impact	2,5	0,59	0,8	57,63	8,68	N	0,32	N	0,7	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15008	15008	T	C	MI.8885	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	262	88	S	P	Tca/Cca	-6,93	0	0	probably_damaging	1	neutral	0,2	neutral	3	deleterious	-3,63	deleterious	-4,29	high_impact	5,42	neutral	0,88	damaging	0,04	deleterious	3,78	23,4	0,05	0,35	disease	0,87	disease	0,89	disease	0,82	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,1	high_impact	3,73	0,36	0,8	57,63	8,68	P	0,74	P	1	polymorphism	1	0,19	.	.	.	.	.	.	COSM1155585	.	.	.	.	.	.	.	.
chrM	15009	15009	C	G	MI.8886	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	263	88	S	W	tCa/tGa	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	2,98	deleterious	-4,5	deleterious	-6,02	high_impact	5,42	neutral	0,89	damaging	0,09	deleterious	4,27	24	0,05	0,35	disease	0,98	disease	0,94	disease	0,76	disease	0,63	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,14	high_impact	3,73	0,13	0,8	57,63	8,68	P	0,7	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15009	15009	C	T	MI.8887	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	263	88	S	L	tCa/tTa	7,3	1	0	probably_damaging	1	neutral	0,69	neutral	3,12	neutral	-0,93	deleterious	-5,15	high_impact	5,07	neutral	0,88	damaging	0,06	deleterious	4,56	24,4	0,04	0,35	disease	0,89	disease	0,93	disease	0,69	disease	0,63	3	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,41	high_impact	3,41	0,57	0,8	57,63	8,68	P	0,7	P	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15011	15011	A	G	MI.8888	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	265	89	M	V	Ata/Gta	-5,32	0	0	probably_damaging	0,98	neutral	0,43	neutral	3,18	neutral	-0,1	neutral	-1,67	medium_impact	2,5	neutral	0,86	neutral	0,64	neutral	0,97	10,48	0,28	0,45	neutral	0,43	disease	0,84	disease	0,61	disease	0,58	2	neutral	0,97	neutral	0,23	deleterious	1	deleterious	0,75	low_impact	-2,31	medium_impact	0,16	medium_impact	1,08	0,33	0,8	20,26	11,43	N	0,25	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15011	15011	A	T	MI.8889	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	265	89	M	L	Ata/Tta	-5,32	0	0	probably_damaging	0,96	neutral	0,77	neutral	3,29	neutral	0,99	neutral	-0,72	neutral_impact	0,27	neutral	0,91	neutral	0,73	deleterious	0,3	5,65	0,23	0,45	neutral	0,16	disease	0,74	neutral	0,44	neutral	0,22	6	neutral	0,96	neutral	0,41	neutral	-2	deleterious	0,66	low_impact	-2,02	medium_impact	0,51	medium_impact	-0,95	0,27	0,8	20,26	11,43	N	0,22	N	0,92	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8944	8944	A	C	MI.889	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	418	140	M	L	Ata/Cta	-15,14	0	0	possibly_damaging	0,81	neutral	0,29	neutral	4,57	neutral	1,99	neutral	-1,45	neutral_impact	-0,2	neutral	0,87	neutral	0,64	deleterious	2,19	17,41	0,37	0,65	neutral	0,29	neutral	0,34	neutral	0,38	neutral	0,44	1	neutral	0,85	neutral	0,24	neutral	-3	deleterious	0,5	low_impact	-1,35	medium_impact	0,07	low_impact	-1,27	0,59	0,9	44,25	8,21	N	0,38	N	0,93	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15011	15011	A	C	MI.8890	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	265	89	M	L	Ata/Cta	-5,32	0	0	probably_damaging	0,96	neutral	0,77	neutral	3,29	neutral	0,99	neutral	-0,72	neutral_impact	0,27	neutral	0,91	neutral	0,73	deleterious	0,16	4,23	0,23	0,45	neutral	0,16	disease	0,74	neutral	0,44	neutral	0,22	6	neutral	0,96	neutral	0,41	neutral	-2	deleterious	0,66	low_impact	-2,02	medium_impact	0,51	medium_impact	-0,95	0,27	0,8	20,26	11,43	N	0,22	N	0,92	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15012	15012	T	A	MI.8891	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	266	89	M	K	aTa/aAa	0,64	0,25	0	probably_damaging	0,99	neutral	0,25	neutral	3,07	neutral	-2,5	deleterious	-3,7	high_impact	4,25	neutral	0,82	neutral	0,37	deleterious	2,38	18,7	0,02	0,35	disease	0,81	disease	0,94	disease	0,73	disease	0,74	5	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,88	low_impact	-2,59	medium_impact	-0,04	high_impact	2,67	0,17	0,8	20,26	11,43	N	0,39	N	0,99	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15012	15012	T	C	MI.8892	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	266	89	M	T	aTa/aCa	0,64	0,25	0	probably_damaging	1	neutral	0,33	neutral	3,11	neutral	-0,9	deleterious	-3,1	medium_impact	3,27	neutral	0,91	neutral	0,62	deleterious	2,58	19,95	0,07	0,35	disease	0,65	disease	0,84	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,82	low_impact	-3,53	medium_impact	0,06	medium_impact	1,78	0,15	0,8	20,26	11,43	N	0,34	N	0,99	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15013	15013	A	T	MI.8893	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	267	89	M	I	atA/atT	7,3	0,98	0,01	probably_damaging	0,98	neutral	0,43	neutral	3,28	neutral	0,9	neutral	-1,17	medium_impact	2,08	neutral	0,9	neutral	0,43	neutral	1,5	13,3	0,26	0,45	neutral	0,39	disease	0,85	neutral	0,5	neutral	0,17	7	deleterious	0,98	neutral	0,23	deleterious	1	deleterious	0,78	low_impact	-2,31	medium_impact	0,16	medium_impact	0,7	0,37	0,8	20,26	11,43	N	0,54	P	0,95	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15013	15013	A	C	MI.8894	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	267	89	M	I	atA/atC	7,3	0,98	0,01	probably_damaging	0,98	neutral	0,43	neutral	3,28	neutral	0,9	neutral	-1,17	medium_impact	2,08	neutral	0,9	neutral	0,43	neutral	1,43	12,97	0,26	0,45	neutral	0,39	disease	0,85	neutral	0,5	neutral	0,17	7	deleterious	0,98	neutral	0,23	deleterious	1	deleterious	0,78	low_impact	-2,31	medium_impact	0,16	medium_impact	0,7	0,37	0,8	20,26	11,43	N	0,53	P	0,95	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15014	15014	T	G	MI.8895	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	268	90	F	V	Ttc/Gtc	-0,27	0,35	0	possibly_damaging	0,68	neutral	0,22	neutral	3,01	neutral	-1,71	deleterious	-5,67	high_impact	4	neutral	0,85	neutral	0,5	deleterious	3,97	23,6	0,06	0,35	disease	0,57	disease	0,91	disease	0,73	disease	0,72	4	neutral	0,82	neutral	0,27	deleterious	1	deleterious	0,63	low_impact	-1,04	medium_impact	-0,08	high_impact	2,44	0,45	0,8	19,47	16,72	N	0,41	N	0,9	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15014	15014	T	A	MI.8896	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	268	90	F	I	Ttc/Atc	-0,27	0,35	0	benign	0,36	neutral	0,24	neutral	3,02	neutral	-1,77	deleterious	-4,82	high_impact	3,75	neutral	0,85	neutral	0,49	deleterious	4,2	23,9	0,09	0,4	disease	0,71	disease	0,9	disease	0,72	disease	0,7	4	neutral	0,72	neutral	0,44	neutral	-2	deleterious	0,6	medium_impact	-0,5	medium_impact	-0,05	high_impact	2,21	0,65	0,8	19,47	16,72	N	0,37	N	0,8	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15014	15014	T	C	MI.8897	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	268	90	F	L	Ttc/Ctc	-0,27	0,35	0	benign	0,02	neutral	0,56	neutral	3,08	neutral	-1,5	deleterious	-4,75	high_impact	4,41	neutral	0,85	neutral	0,6	deleterious	3,69	23,3	0,13	0,4	disease	0,58	disease	0,86	disease	0,68	disease	0,56	1	neutral	0,41	deleterious	0,77	neutral	-2	neutral	0,28	medium_impact	0,85	medium_impact	0,28	high_impact	2,81	0,66	0,8	19,47	16,72	N	0,39	N	0,4	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15015	15015	T	G	MI.8898	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	269	90	F	C	tTc/tGc	5,69	1	0	probably_damaging	0,99	neutral	0,08	neutral	2,92	deleterious	-5,21	deleterious	-6,58	high_impact	5,04	neutral	0,84	neutral	0,42	deleterious	4	23,6	0,02	0,35	disease	0,94	disease	0,9	disease	0,75	disease	0,64	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,84	low_impact	-2,59	medium_impact	-0,35	high_impact	3,38	0,29	0,8	19,47	16,72	P	0,69	P	0,96	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15015	15015	T	A	MI.8899	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	269	90	F	Y	tTc/tAc	5,69	1	0	possibly_damaging	0,72	neutral	0,44	neutral	2,97	deleterious	-4,2	neutral	-2,5	high_impact	3,88	neutral	0,85	neutral	0,46	deleterious	4,1	23,7	0,13	0,4	disease	0,65	disease	0,87	disease	0,7	disease	0,7	4	neutral	0,72	neutral	0,36	deleterious	1	deleterious	0,73	low_impact	-1,11	medium_impact	0,17	high_impact	2,33	0,65	0,8	19,47	16,72	P	0,67	P	0,74	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8566	8566	A	C	MI.89	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	40	14	I	L	Atc/Ctc	-0,8	0	0,01	benign	0,09	neutral	1	neutral	4,74	neutral	0,29	neutral	0,14	neutral_impact	-1,74	neutral	0,89	neutral	0,94	deleterious	0,32	5,85	0,48	0,65	neutral	0,32	neutral	0,14	neutral	0,26	neutral	0,23	5	neutral	0,09	deleterious	0,96	neutral	-6	neutral	0,12	medium_impact	0,2	high_impact	1,98	low_impact	-2,59	0,68	0,9	13,72	12,42	N	0,31	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8945	8945	T	C	MI.890	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	419	140	M	T	aTa/aCa	1,98	0,58	0	probably_damaging	0,94	deleterious	0,04	neutral	4,41	neutral	0,4	deleterious	-3,55	low_impact	1,84	neutral	0,91	neutral	0,59	deleterious	1,88	15,47	0,29	0,65	disease	0,79	neutral	0,39	neutral	0,44	disease	0,64	3	deleterious	0,99	neutral	0,05	deleterious	2	deleterious	0,75	low_impact	-1,89	medium_impact	-0,49	medium_impact	0,48	0,41	0,9	44,25	8,21	N	0,38	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15015	15015	T	C	MI.8900	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	269	90	F	S	tTc/tCc	5,69	1	0	probably_damaging	0,94	neutral	0,23	neutral	2,94	deleterious	-4	deleterious	-6,6	high_impact	5,38	neutral	0,84	neutral	0,45	deleterious	4,21	23,9	0,02	0,35	disease	0,88	disease	0,88	disease	0,71	disease	0,63	3	neutral	0,96	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-1,85	medium_impact	-0,06	high_impact	3,69	0,42	0,8	19,47	16,72	P	0,73	P	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15016	15016	C	A	MI.8901	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	270	90	F	L	ttC/ttA	7,3	1	0	benign	0,02	neutral	0,56	neutral	3,08	neutral	-1,5	deleterious	-4,75	high_impact	4,41	neutral	0,85	neutral	0,6	deleterious	4,27	23,9	0,13	0,4	disease	0,58	disease	0,86	disease	0,68	disease	0,56	1	neutral	0,41	deleterious	0,77	neutral	-2	neutral	0,28	medium_impact	0,85	medium_impact	0,28	high_impact	2,81	0,66	0,8	19,47	16,72	P	0,6	P	0,4	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15016	15016	C	G	MI.8902	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	270	90	F	L	ttC/ttG	7,3	1	0	benign	0,02	neutral	0,56	neutral	3,08	neutral	-1,5	deleterious	-4,75	high_impact	4,41	neutral	0,85	neutral	0,6	deleterious	3,98	23,6	0,13	0,4	disease	0,58	disease	0,86	disease	0,68	disease	0,56	1	neutral	0,41	deleterious	0,77	neutral	-2	neutral	0,28	medium_impact	0,85	medium_impact	0,28	high_impact	2,81	0,66	0,8	19,47	16,72	P	0,6	P	0,4	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15017	15017	T	C	MI.8903	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	271	91	F	L	Ttt/Ctt	-1,88	0	0	benign	0,02	neutral	0,4	neutral	3,12	neutral	-1,14	deleterious	-5,18	high_impact	4,65	neutral	0,85	damaging	0,08	deleterious	3,6	23,2	0,08	0,35	neutral	0,42	disease	0,87	disease	0,61	disease	0,68	4	neutral	0,58	deleterious	0,69	neutral	-2	neutral	0,26	medium_impact	0,85	medium_impact	0,13	high_impact	3,03	0,5	0,8	57,63	8,71	N	0,45	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15017	15017	T	A	MI.8904	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	271	91	F	I	Ttt/Att	-1,88	0	0	benign	0,36	neutral	0,31	neutral	3,41	neutral	-0,34	deleterious	-5,18	high_impact	5,11	neutral	0,89	damaging	0,07	deleterious	4,1	23,7	0,07	0,35	disease	0,65	disease	0,92	disease	0,67	disease	0,7	4	neutral	0,63	deleterious	0,48	neutral	-2	deleterious	0,6	medium_impact	-0,5	medium_impact	0,03	high_impact	3,45	0,42	0,8	57,63	8,71	N	0,56	P	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15017	15017	T	G	MI.8905	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	271	91	F	V	Ttt/Gtt	-1,88	0	0	possibly_damaging	0,68	neutral	0,14	neutral	3,19	neutral	0,4	deleterious	-6,05	high_impact	4,76	neutral	0,84	damaging	0,08	deleterious	3,81	23,4	0,05	0,35	disease	0,69	disease	0,92	disease	0,7	disease	0,71	4	neutral	0,88	neutral	0,23	deleterious	1	deleterious	0,65	low_impact	-1,04	medium_impact	-0,21	high_impact	3,13	0,37	0,8	57,63	8,71	N	0,54	P	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15018	15018	T	C	MI.8906	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	272	91	F	S	tTt/tCt	5,69	1	0	probably_damaging	0,99	neutral	0,16	neutral	3,01	deleterious	-3,17	deleterious	-6,91	high_impact	5,11	neutral	0,86	damaging	0,06	deleterious	4,15	23,8	0,03	0,35	disease	0,89	disease	0,9	disease	0,64	disease	0,62	2	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,85	low_impact	-2,59	medium_impact	-0,17	high_impact	3,45	0,37	0,8	57,63	8,71	P	0,7	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15018	15018	T	G	MI.8907	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	272	91	F	C	tTt/tGt	5,69	1	0	probably_damaging	0,99	neutral	0,1	neutral	2,98	deleterious	-4,44	deleterious	-6,92	high_impact	5,46	neutral	0,87	damaging	0,06	deleterious	4,01	23,6	0,03	0,35	disease	0,94	disease	0,91	disease	0,69	disease	0,61	2	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,84	low_impact	-2,59	medium_impact	-0,3	high_impact	3,76	0,32	0,8	57,63	8,71	P	0,67	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15018	15018	T	A	MI.8908	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	272	91	F	Y	tTt/tAt	5,69	1	0	possibly_damaging	0,72	neutral	0,32	neutral	2,99	deleterious	-3,49	deleterious	-2,59	high_impact	5,11	neutral	0,91	damaging	0,07	deleterious	3,89	23,5	0,1	0,4	disease	0,69	disease	0,88	disease	0,62	disease	0,68	4	neutral	0,77	neutral	0,3	deleterious	1	deleterious	0,74	low_impact	-1,11	medium_impact	0,05	high_impact	3,45	0,48	0,8	57,63	8,71	P	0,75	P	0,87	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15019	15019	T	A	MI.8909	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	273	91	F	L	ttT/ttA	5,69	1	0	benign	0,02	neutral	0,4	neutral	3,12	neutral	-1,14	deleterious	-5,18	high_impact	4,65	neutral	0,85	damaging	0,08	deleterious	4,12	23,8	0,08	0,35	neutral	0,42	disease	0,87	disease	0,61	disease	0,68	4	neutral	0,58	deleterious	0,69	neutral	-2	neutral	0,26	medium_impact	0,85	medium_impact	0,13	high_impact	3,03	0,5	0,8	57,63	8,71	P	0,58	P	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8945	8945	T	A	MI.891	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	419	140	M	K	aTa/aAa	1,98	0,58	0	probably_damaging	0,94	deleterious	0	neutral	4,35	neutral	-1,39	deleterious	-4,25	medium_impact	2,4	neutral	0,83	neutral	0,39	deleterious	3,96	23,6	0,16	0,65	disease	0,9	disease	0,64	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,82	low_impact	-1,89	low_impact	-1,4	medium_impact	0,96	0,52	0,9	44,25	8,21	N	0,28	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15019	15019	T	G	MI.8910	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	273	91	F	L	ttT/ttG	5,69	1	0	benign	0,02	neutral	0,4	neutral	3,12	neutral	-1,14	deleterious	-5,18	high_impact	4,65	neutral	0,85	damaging	0,08	deleterious	4	23,6	0,08	0,35	neutral	0,42	disease	0,87	disease	0,61	disease	0,68	4	neutral	0,58	deleterious	0,69	neutral	-2	neutral	0,26	medium_impact	0,85	medium_impact	0,13	high_impact	3,03	0,5	0,8	57,63	8,71	P	0,58	P	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15020	15020	A	C	MI.8911	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	274	92	I	L	Atc/Ctc	-1,65	0	0	probably_damaging	0,95	neutral	0,48	neutral	2,96	neutral	-1,95	neutral	-1,5	medium_impact	2,17	neutral	0,86	neutral	0,68	deleterious	1,8	15,01	0,16	0,45	neutral	0,31	disease	0,7	neutral	0,39	neutral	0,17	7	neutral	0,95	neutral	0,27	deleterious	1	deleterious	0,58	low_impact	-1,92	medium_impact	0,2	medium_impact	0,78	0,43	0,8	23,42	22,23	N	0,26	N	0,65	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15020	15020	A	T	MI.8912	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	274	92	I	F	Atc/Ttc	-1,65	0	0	probably_damaging	0,99	neutral	1	neutral	2,84	neutral	-1,24	deleterious	-2,99	medium_impact	3,02	neutral	0,83	neutral	0,58	deleterious	2,07	16,67	0,09	0,35	neutral	0,47	disease	0,86	disease	0,55	neutral	0,49	0	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,78	low_impact	-2,59	high_impact	1,85	medium_impact	1,55	0,56	0,8	23,42	22,23	N	0,19	N	0,95	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15020	15020	A	G	MI.8913	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	274	92	I	V	Atc/Gtc	-1,65	0	0	possibly_damaging	0,88	neutral	0,31	neutral	2,99	neutral	-1,97	neutral	-0,79	medium_impact	2,38	neutral	0,96	neutral	0,8	neutral	1,04	10,89	0,18	0,45	neutral	0,43	disease	0,52	neutral	0,43	neutral	0,17	7	neutral	0,89	neutral	0,22	NA	0	deleterious	0,55	low_impact	-1,54	medium_impact	0,03	medium_impact	0,97	0,4	0,8	23,42	22,23	N	0,39	N	0,51	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15021	15021	T	G	MI.8914	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	275	92	I	S	aTc/aGc	4,54	0,99	0	probably_damaging	1	neutral	0,36	neutral	2,83	neutral	-1,18	deleterious	-4,88	high_impact	4,46	neutral	0,84	neutral	0,37	deleterious	3,89	23,5	0,02	0,35	disease	0,75	disease	0,88	disease	0,62	disease	0,67	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,09	high_impact	2,86	0,3	0,8	23,42	22,23	P	0,57	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15021	15021	T	A	MI.8915	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	275	92	I	N	aTc/aAc	4,54	0,99	0	probably_damaging	1	neutral	0,22	neutral	2,8	deleterious	-4,53	deleterious	-5,75	high_impact	4,59	neutral	0,86	neutral	0,39	deleterious	4,12	23,8	0,04	0,35	disease	0,86	disease	0,88	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,08	high_impact	2,97	0,35	0,8	23,42	22,23	P	0,61	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15021	15021	T	C	MI.8916	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	275	92	I	T	aTc/aCc	4,54	0,99	0	probably_damaging	1	neutral	0,23	neutral	2,84	deleterious	-3,16	deleterious	-4,06	high_impact	4,59	neutral	0,82	neutral	0,5	deleterious	2,91	21,9	0,03	0,35	disease	0,68	disease	0,82	disease	0,56	disease	0,63	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	-0,06	high_impact	2,97	0,21	0,8	23,42	22,23	P	0,61	P	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15022	15022	C	G	MI.8917	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	276	92	I	M	atC/atG	3,63	0,99	0,01	probably_damaging	1	neutral	0,22	neutral	2,87	deleterious	-3,55	neutral	-2,17	medium_impact	2,4	neutral	0,88	neutral	0,82	neutral	1,71	14,44	0,11	0,4	neutral	0,38	disease	0,59	disease	0,52	neutral	0,19	6	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,69	low_impact	-3,53	medium_impact	-0,08	medium_impact	0,99	0,47	0,8	23,42	22,23	N	0,5	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15022	15022	C	A	MI.8918	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	276	92	I	M	atC/atA	3,63	0,99	0,01	probably_damaging	1	neutral	0,22	neutral	2,87	deleterious	-3,55	neutral	-2,17	medium_impact	2,4	neutral	0,88	neutral	0,82	deleterious	2,06	16,6	0,11	0,4	neutral	0,38	disease	0,59	disease	0,52	neutral	0,19	6	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,69	low_impact	-3,53	medium_impact	-0,08	medium_impact	0,99	0,47	0,8	23,42	22,23	N	0,51	P	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15023	15023	T	A	MI.8919	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	277	93	C	S	Tgc/Agc	-3,49	0	0	probably_damaging	1	neutral	0,47	neutral	3,19	neutral	-0,94	deleterious	-8,57	high_impact	3,58	neutral	0,83	neutral	0,46	deleterious	3,37	22,9	0,06	0,35	disease	0,6	disease	0,92	disease	0,61	disease	0,59	2	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,19	high_impact	2,06	0,48	0,8	57,63	8,31	N	0,32	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8946	8946	A	C	MI.892	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	420	140	M	I	atA/atC	2,44	0,6	0	probably_damaging	0,91	neutral	0,33	neutral	4,45	neutral	0,89	neutral	-1,4	neutral_impact	-0,52	neutral	0,86	neutral	0,57	deleterious	1,89	15,52	0,38	0,65	neutral	0,3	neutral	0,19	neutral	0,33	neutral	0,32	4	neutral	0,92	neutral	0,21	neutral	-2	deleterious	0,6	low_impact	-1,71	medium_impact	0,12	low_impact	-1,54	0,7	0,9	44,25	8,21	N	0,32	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15023	15023	T	G	MI.8920	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	277	93	C	G	Tgc/Ggc	-3,49	0	0	probably_damaging	1	neutral	0,54	neutral	3,12	deleterious	-3,46	deleterious	-10,33	high_impact	4,13	neutral	0,83	neutral	0,47	deleterious	3,19	22,7	0,05	0,35	disease	0,73	disease	0,94	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,26	high_impact	2,56	0,41	0,8	57,63	8,31	N	0,38	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15023	15023	T	C	MI.8921	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	277	93	C	R	Tgc/Cgc	-3,49	0	0	probably_damaging	1	neutral	0,3	neutral	3,11	deleterious	-3,35	deleterious	-10,34	high_impact	5,17	neutral	0,84	neutral	0,36	deleterious	3,39	23	0,04	0,35	disease	0,73	disease	0,97	disease	0,76	disease	0,79	6	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0,02	high_impact	3,5	0,13	0,8	57,63	8,31	P	0,67	P	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15024	15024	G	A	MI.8922	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	278	93	C	Y	tGc/tAc	5,69	1	0,01	probably_damaging	1	neutral	1	neutral	3,12	deleterious	-3,08	deleterious	-9,46	high_impact	4,82	neutral	0,77	neutral	0,41	deleterious	3,49	23,1	0,06	0,35	disease	0,66	disease	0,97	disease	0,69	disease	0,77	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,87	low_impact	-3,53	high_impact	1,85	high_impact	3,18	0,35	0,8	57,63	8,31	P	0,63	P	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	G15024A	Possible DEAF modifier	+	-	Reported	1
chrM	15024	15024	G	C	MI.8923	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	278	93	C	S	tGc/tCc	5,69	1	0,01	probably_damaging	1	neutral	0,47	neutral	3,19	neutral	-0,94	deleterious	-8,57	high_impact	3,58	neutral	0,83	neutral	0,46	deleterious	3,07	22,4	0,06	0,35	disease	0,6	disease	0,92	disease	0,61	disease	0,59	2	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,19	high_impact	2,06	0,48	0,8	57,63	8,31	N	0,5	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15024	15024	G	T	MI.8924	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	278	93	C	F	tGc/tTc	5,69	1	0,01	probably_damaging	1	neutral	0,98	neutral	3,2	neutral	-2,63	deleterious	-9,46	medium_impact	2,25	neutral	0,91	neutral	0,54	deleterious	3,76	23,3	0,05	0,35	neutral	0,27	disease	0,97	disease	0,63	disease	0,61	2	deleterious	1	deleterious	0,49	deleterious	1	deleterious	0,83	low_impact	-3,53	medium_impact	1,14	medium_impact	0,85	0,33	0,8	57,63	8,31	N	0,43	N	0,66	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15025	15025	C	G	MI.8925	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	279	93	C	W	tgC/tgG	5	1	0	probably_damaging	1	neutral	0,14	neutral	3,1	neutral	-2,74	deleterious	-9,47	high_impact	4,62	neutral	0,84	neutral	0,38	deleterious	4,24	23,9	0,04	0,35	disease	0,85	disease	0,96	disease	0,73	disease	0,67	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,21	high_impact	3	0,24	0,8	57,63	8,31	P	0,61	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15025	15025	C	A	MI.8926	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	279	93	C	W	tgC/tgA	5	1	0	probably_damaging	1	neutral	0,14	neutral	3,1	neutral	-2,74	deleterious	-9,47	high_impact	4,62	neutral	0,84	neutral	0,38	deleterious	4,57	24,4	0,04	0,35	disease	0,85	disease	0,96	disease	0,73	disease	0,67	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,21	high_impact	3	0,24	0,8	57,63	8,31	P	0,61	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15026	15026	C	G	MI.8927	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	280	94	L	V	Ctc/Gtc	-1,42	0	0	probably_damaging	0,99	neutral	0,35	neutral	3,17	neutral	1,28	neutral	-0,21	low_impact	1,52	neutral	0,91	damaging	0,11	deleterious	3,07	22,4	0,14	0,4	neutral	0,18	disease	0,72	neutral	0,36	neutral	0,2	6	deleterious	0,99	neutral	0,18	neutral	-2	deleterious	0,68	low_impact	-2,59	medium_impact	0,08	medium_impact	0,19	0,55	0,8	56,84	8,43	N	0,3	N	0,91	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15026	15026	C	A	MI.8928	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	280	94	L	I	Ctc/Atc	-1,42	0	0	probably_damaging	1	neutral	0,57	neutral	3,2	neutral	0,51	neutral	0,63	neutral_impact	-0,02	neutral	0,89	damaging	0,13	deleterious	2,24	17,8	0,15	0,45	neutral	0,27	neutral	0,1	neutral	0,25	neutral	0,29	4	deleterious	1	neutral	0,29	neutral	-2	deleterious	0,65	low_impact	-3,53	medium_impact	0,29	low_impact	-1,21	0,43	0,8	56,84	8,43	N	0,31	N	0,86	polymorphism	1	0,01	rs879178244	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15026	15026	C	T	MI.8929	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	280	94	L	F	Ctc/Ttc	-1,42	0	0	probably_damaging	1	neutral	0,83	neutral	3	deleterious	-3,21	neutral	-2,29	high_impact	3,7	neutral	0,88	damaging	0,09	deleterious	3,9	23,5	0,07	0,35	disease	0,63	disease	0,84	disease	0,59	disease	0,7	4	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,6	high_impact	2,17	0,58	0,8	56,84	8,43	N	0,2	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8946	8946	A	T	MI.893	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	420	140	M	I	atA/atT	2,44	0,6	0	probably_damaging	0,91	neutral	0,33	neutral	4,45	neutral	0,89	neutral	-1,4	neutral_impact	-0,52	neutral	0,86	neutral	0,57	deleterious	1,95	15,91	0,38	0,65	neutral	0,3	neutral	0,19	neutral	0,33	neutral	0,32	4	neutral	0,92	neutral	0,21	neutral	-2	deleterious	0,6	low_impact	-1,71	medium_impact	0,12	low_impact	-1,54	0,7	0,9	44,25	8,21	N	0,33	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15027	15027	T	A	MI.8930	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	281	94	L	H	cTc/cAc	-0,5	0	0	probably_damaging	1	neutral	0,44	neutral	2,96	deleterious	-4,99	deleterious	-4,89	high_impact	4,5	neutral	0,85	damaging	0,07	deleterious	4,04	23,7	0,02	0,35	disease	0,86	disease	0,87	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,17	high_impact	2,89	0,31	0,8	56,84	8,43	N	0,42	N	0,95	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15027	15027	T	G	MI.8931	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	281	94	L	R	cTc/cGc	-0,5	0	0	probably_damaging	1	neutral	0,27	neutral	2,97	deleterious	-4,39	deleterious	-4,61	high_impact	4,5	neutral	0,87	damaging	0,06	deleterious	4,12	23,8	0,01	0,35	disease	0,81	disease	0,95	disease	0,7	disease	0,76	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,01	high_impact	2,89	0,22	0,8	56,84	8,43	N	0,43	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15027	15027	T	C	MI.8932	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	281	94	L	P	cTc/cCc	-0,5	0	0	probably_damaging	1	neutral	0,18	neutral	2,96	deleterious	-4,86	deleterious	-4,88	high_impact	4,5	neutral	0,87	damaging	0,06	deleterious	3,8	23,4	0,01	0,35	disease	0,85	disease	0,94	disease	0,71	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,14	high_impact	2,89	0,43	0,8	56,84	8,43	N	0,43	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15029	15029	T	C	MI.8933	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	283	95	F	L	Ttc/Ctc	-4,17	0	0	benign	0,26	neutral	0,6	neutral	3,25	neutral	1,5	deleterious	-3,78	medium_impact	2,56	neutral	0,93	neutral	0,46	deleterious	2,26	17,9	0,11	0,4	disease	0,71	disease	0,82	disease	0,61	disease	0,73	5	neutral	0,29	deleterious	0,67	neutral	-3	deleterious	0,57	medium_impact	-0,31	medium_impact	0,32	medium_impact	1,13	0,42	0,8	57,37	9,26	N	0,27	N	0,85	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15029	15029	T	A	MI.8934	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	283	95	F	I	Ttc/Atc	-4,17	0	0	possibly_damaging	0,44	neutral	0,65	neutral	3,19	neutral	2,92	deleterious	-3,78	medium_impact	2,75	neutral	0,94	neutral	0,49	deleterious	3,95	23,6	0,1	0,4	disease	0,85	disease	0,84	disease	0,62	disease	0,72	4	neutral	0,36	deleterious	0,61	NA	0	deleterious	0,67	medium_impact	-0,63	medium_impact	0,37	medium_impact	1,3	0,37	0,8	57,37	9,26	N	0,28	N	0,81	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15029	15029	T	G	MI.8935	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	283	95	F	V	Ttc/Gtc	-4,17	0	0	possibly_damaging	0,56	neutral	0,31	neutral	3,18	neutral	3,12	deleterious	-3,93	medium_impact	3,45	neutral	0,95	neutral	0,56	deleterious	3,77	23,4	0,08	0,35	disease	0,84	disease	0,89	disease	0,64	disease	0,7	4	neutral	0,69	neutral	0,38	NA	0	deleterious	0,68	medium_impact	-0,83	medium_impact	0,03	medium_impact	1,94	0,27	0,8	57,37	9,26	N	0,38	N	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15030	15030	T	C	MI.8936	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	284	95	F	S	tTc/tCc	5,69	0,87	0	benign	0,05	neutral	0,27	neutral	3,1	neutral	-0,53	deleterious	-4,8	medium_impact	3,45	neutral	0,96	neutral	0,63	deleterious	3,99	23,6	0,04	0,35	disease	0,87	disease	0,81	disease	0,63	disease	0,71	4	neutral	0,71	deleterious	0,61	neutral	-3	neutral	0,35	medium_impact	0,46	medium_impact	-0,01	medium_impact	1,94	0,23	0,8	57,37	9,26	N	0,49	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15030	15030	T	A	MI.8937	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	284	95	F	Y	tTc/tAc	5,69	0,87	0	possibly_damaging	0,52	neutral	1	neutral	3,41	neutral	3,17	neutral	2,46	neutral_impact	-1,88	neutral	0,97	neutral	0,81	neutral	-0,21	1,05	0,13	0,4	neutral	0,14	neutral	0,12	neutral	0,39	neutral	0,26	5	neutral	0,52	deleterious	0,74	neutral	-3	deleterious	0,49	medium_impact	-0,76	high_impact	1,85	low_impact	-2,9	0,48	0,8	57,37	9,26	N	0,45	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15030	15030	T	G	MI.8938	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	284	95	F	C	tTc/tGc	5,69	0,87	0	probably_damaging	0,93	neutral	0,15	neutral	3,07	neutral	-1,65	deleterious	-4,81	medium_impact	3,45	neutral	0,94	neutral	0,41	deleterious	4,01	23,6	0,04	0,35	disease	0,94	disease	0,9	disease	0,66	disease	0,7	4	neutral	0,96	neutral	0,11	deleterious	1	deleterious	0,85	low_impact	-1,78	medium_impact	-0,19	medium_impact	1,94	0,17	0,8	57,37	9,26	N	0,51	P	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15031	15031	C	G	MI.8939	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	285	95	F	L	ttC/ttG	-0,5	0	0	benign	0,26	neutral	0,6	neutral	3,25	neutral	1,5	deleterious	-3,78	medium_impact	2,56	neutral	0,93	neutral	0,46	deleterious	2,63	20,4	0,11	0,4	disease	0,71	disease	0,82	disease	0,61	disease	0,73	5	neutral	0,29	deleterious	0,67	neutral	-3	deleterious	0,57	medium_impact	-0,31	medium_impact	0,32	medium_impact	1,13	0,42	0,8	57,37	9,26	N	0,28	N	0,85	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8947	8947	C	A	MI.894	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	421	141	L	M	Cta/Ata	-1,95	0	0	probably_damaging	1	neutral	0,87	neutral	4,22	neutral	-1,91	neutral	-1,74	low_impact	1,79	neutral	0,6	damaging	0,17	deleterious	3,7	23,3	0,32	0,65	neutral	0,46	neutral	0,08	neutral	0,34	neutral	0,3	4	deleterious	1	neutral	0,44	neutral	-2	deleterious	0,69	low_impact	-3,6	medium_impact	0,76	medium_impact	0,44	0,75	0,9	46,46	8,22	N	0,26	N	0,96	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15031	15031	C	A	MI.8940	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	285	95	F	L	ttC/ttA	-0,5	0	0	benign	0,26	neutral	0,6	neutral	3,25	neutral	1,5	deleterious	-3,78	medium_impact	2,56	neutral	0,93	neutral	0,46	deleterious	2,96	22,1	0,11	0,4	disease	0,71	disease	0,82	disease	0,61	disease	0,73	5	neutral	0,29	deleterious	0,67	neutral	-3	deleterious	0,57	medium_impact	-0,31	medium_impact	0,32	medium_impact	1,13	0,42	0,8	57,37	9,26	N	0,28	N	0,85	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15032	15032	C	G	MI.8941	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	286	96	L	V	Cta/Gta	-3,03	0	0	probably_damaging	0,98	neutral	0,33	neutral	3,24	deleterious	-4,61	neutral	-1,88	medium_impact	3,13	neutral	0,93	neutral	0,42	neutral	1,65	14,15	0,18	0,45	disease	0,56	disease	0,73	neutral	0,39	neutral	0,36	3	neutral	0,98	neutral	0,18	deleterious	1	deleterious	0,75	low_impact	-2,31	medium_impact	0,06	medium_impact	1,65	0,53	0,8	15,26	27,57	N	0,36	N	0,69	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15032	15032	C	A	MI.8942	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	286	96	L	M	Cta/Ata	-3,03	0	0	probably_damaging	1	neutral	0,31	neutral	2,94	deleterious	-5,28	neutral	-0,66	low_impact	1,68	neutral	0,94	neutral	0,81	deleterious	2,18	17,4	0,18	0,45	neutral	0,37	neutral	0,34	neutral	0,35	neutral	0,44	1	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,68	low_impact	-3,53	medium_impact	0,03	medium_impact	0,33	0,4	0,8	15,26	27,57	N	0,45	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15033	15033	T	C	MI.8943	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	287	96	L	P	cTa/cCa	-1,88	0	0	probably_damaging	1	neutral	0,1	neutral	2,9	deleterious	-7,5	deleterious	-5,07	high_impact	4,87	neutral	0,87	damaging	0,09	deleterious	3,78	23,4	0,02	0,35	disease	0,93	disease	0,91	disease	0,7	disease	0,64	3	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,3	high_impact	3,23	0,33	0,8	15,26	27,57	P	0,62	P	0,93	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15033	15033	T	A	MI.8944	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	287	96	L	Q	cTa/cAa	-1,88	0	0	probably_damaging	1	neutral	0,14	neutral	2,9	deleterious	-6,8	deleterious	-4,09	high_impact	4,87	neutral	0,86	damaging	0,14	deleterious	3,94	23,5	0,02	0,35	disease	0,91	disease	0,82	disease	0,58	disease	0,63	3	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,21	high_impact	3,23	0,3	0,8	15,26	27,57	P	0,66	P	0,91	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15033	15033	T	G	MI.8945	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	287	96	L	R	cTa/cGa	-1,88	0	0	probably_damaging	1	neutral	0,2	neutral	2,9	deleterious	-6,73	deleterious	-4,28	high_impact	4,87	neutral	0,87	damaging	0,09	deleterious	4,06	23,7	0,01	0,35	disease	0,91	disease	0,93	disease	0,69	disease	0,65	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,1	high_impact	3,23	0,24	0,8	15,26	27,57	P	0,66	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15035	15035	C	G	MI.8946	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	289	97	H	D	Cac/Gac	-20	0	0	probably_damaging	1	neutral	0,19	neutral	1,79	deleterious	-8,41	deleterious	-7,87	high_impact	5,47	neutral	0,84	damaging	0,08	deleterious	3,63	23,2	0,04	0,35	disease	0,93	disease	0,9	disease	0,85	disease	0,65	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,12	high_impact	3,77	0,27	0,8	56,84	8,72	P	0,59	P	0,98	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15035	15035	C	A	MI.8947	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	289	97	H	N	Cac/Aac	-20	0	0	probably_damaging	1	neutral	0,28	neutral	1,79	deleterious	-7,58	deleterious	-6,12	high_impact	5,47	neutral	0,85	damaging	0,1	deleterious	3,5	23,1	0,15	0,4	disease	0,95	disease	0,88	disease	0,8	disease	0,64	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0	high_impact	3,77	0,39	0,8	56,84	8,72	P	0,64	P	0,97	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15035	15035	C	T	MI.8948	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	289	97	H	Y	Cac/Tac	-20	0	0	probably_damaging	1	neutral	1	neutral	1,78	deleterious	-7,46	deleterious	-5,25	high_impact	4,58	neutral	0,9	damaging	0,09	deleterious	3,32	22,9	0,09	0,35	disease	0,92	disease	0,92	disease	0,83	disease	0,64	3	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,89	low_impact	-3,53	high_impact	1,85	high_impact	2,97	0,28	0,8	56,84	8,72	N	0,43	N	1	polymorphism	1	0,22	.	.	.	.	.	.	COSM1138292	.	.	.	.	.	.	.	.
chrM	15036	15036	A	G	MI.8949	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	290	97	H	R	cAc/cGc	5,46	1	0	probably_damaging	1	neutral	0,33	neutral	1,82	deleterious	-7,39	deleterious	-7	high_impact	5,47	neutral	0,86	damaging	0,07	deleterious	2,52	19,61	0,07	0,35	disease	0,93	disease	0,92	disease	0,82	disease	0,64	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,06	high_impact	3,77	0,41	0,8	56,84	8,72	P	0,71	P	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8947	8947	C	G	MI.895	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	421	141	L	V	Cta/Gta	-1,95	0	0	probably_damaging	0,99	neutral	0,14	neutral	4,08	neutral	-1,45	deleterious	-2,53	medium_impact	3,14	damaging	0,58	damaging	0,16	deleterious	3,44	23	0,33	0,65	disease	0,69	neutral	0,5	disease	0,66	disease	0,65	3	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,77	low_impact	-2,65	medium_impact	-0,15	medium_impact	1,59	0,68	0,9	46,46	8,22	N	0,31	N	0,87	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15036	15036	A	T	MI.8950	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	290	97	H	L	cAc/cTc	5,46	1	0	probably_damaging	1	neutral	0,73	neutral	1,79	deleterious	-8,16	deleterious	-9,62	high_impact	5,12	neutral	0,88	damaging	0,08	deleterious	3,35	22,9	0,03	0,35	disease	0,94	disease	0,94	disease	0,8	disease	0,64	3	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,46	high_impact	3,46	0,19	0,8	56,84	8,72	P	0,68	P	0,92	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15036	15036	A	C	MI.8951	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	290	97	H	P	cAc/cCc	5,46	1	0	probably_damaging	1	neutral	0,18	neutral	1,77	deleterious	-9,08	deleterious	-8,75	high_impact	5,47	neutral	0,9	damaging	0,07	deleterious	2,99	22,2	0,03	0,35	disease	0,96	disease	0,91	disease	0,87	disease	0,67	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,14	high_impact	3,77	0,23	0,8	56,84	8,72	P	0,65	P	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15037	15037	C	A	MI.8952	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	291	97	H	Q	caC/caA	6,84	1	0	probably_damaging	1	neutral	0,27	neutral	1,82	deleterious	-6,38	deleterious	-7	high_impact	5,47	neutral	0,88	damaging	0,08	deleterious	3,6	23,2	0,09	0,4	disease	0,95	disease	0,85	disease	0,8	disease	0,69	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,01	high_impact	3,77	0,44	0,8	56,84	8,72	P	0,71	P	0,94	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15037	15037	C	G	MI.8953	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	291	97	H	Q	caC/caG	6,84	1	0	probably_damaging	1	neutral	0,27	neutral	1,82	deleterious	-6,38	deleterious	-7	high_impact	5,47	neutral	0,88	damaging	0,08	deleterious	3,18	22,7	0,09	0,4	disease	0,95	disease	0,85	disease	0,8	disease	0,69	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,01	high_impact	3,77	0,44	0,8	56,84	8,72	P	0,71	P	0,94	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15038	15038	A	C	MI.8954	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	292	98	I	L	Atc/Ctc	-2,34	0	0,02	probably_damaging	0,95	neutral	0,65	neutral	3,3	neutral	0,31	neutral	-1,68	high_impact	3,7	neutral	0,84	neutral	0,52	neutral	1,71	14,45	0,24	0,45	neutral	0,43	disease	0,81	neutral	0,5	disease	0,64	3	neutral	0,94	neutral	0,35	deleterious	2	deleterious	0,67	low_impact	-1,92	medium_impact	0,37	high_impact	2,17	0,54	0,8	16,32	19,7	N	0,25	N	0,63	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15038	15038	A	G	MI.8955	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	292	98	I	V	Atc/Gtc	-2,34	0	0,02	possibly_damaging	0,88	neutral	0,5	neutral	3,15	neutral	-0,56	neutral	-0,55	low_impact	1,74	neutral	0,97	neutral	0,97	neutral	-1,49	0	0,28	0,45	neutral	0,2	neutral	0,23	neutral	0,4	neutral	0,36	3	neutral	0,86	neutral	0,31	neutral	-3	deleterious	0,54	low_impact	-1,54	medium_impact	0,22	medium_impact	0,39	0,43	0,8	16,32	19,7	N	0,4	N	0	polymorphism	1	0,01	rs202045169	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15038	15038	A	T	MI.8956	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	292	98	I	F	Atc/Ttc	-2,34	0	0,02	probably_damaging	0,99	neutral	0,71	neutral	3,05	neutral	-1,98	deleterious	-3,41	high_impact	4,16	neutral	0,85	neutral	0,57	deleterious	1,96	15,95	0,09	0,35	disease	0,76	disease	0,88	disease	0,63	disease	0,69	4	deleterious	0,99	neutral	0,36	deleterious	2	deleterious	0,83	low_impact	-2,59	medium_impact	0,43	high_impact	2,58	0,56	0,8	16,32	19,7	N	0,28	N	0,93	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15039	15039	T	G	MI.8957	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	293	98	I	S	aTc/aGc	0,41	0,02	0	probably_damaging	1	neutral	0,4	neutral	3,01	neutral	-2,21	deleterious	-4,92	high_impact	5,2	neutral	0,84	neutral	0,53	deleterious	3,94	23,5	0,02	0,35	disease	0,85	disease	0,88	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,13	high_impact	3,53	0,25	0,8	16,32	19,7	P	0,68	P	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15039	15039	T	C	MI.8958	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	293	98	I	T	aTc/aCc	0,41	0,02	0	probably_damaging	1	neutral	0,39	neutral	3,03	neutral	-1,58	deleterious	-3,86	high_impact	3,75	neutral	0,77	neutral	0,65	deleterious	2,91	21,9	0,06	0,35	disease	0,74	disease	0,81	disease	0,56	disease	0,62	2	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,12	high_impact	2,21	0,26	0,8	16,32	19,7	N	0,35	N	0,91	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15039	15039	T	A	MI.8959	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	293	98	I	N	aTc/aAc	0,41	0,02	0	probably_damaging	1	neutral	0,3	neutral	2,99	deleterious	-3,48	deleterious	-5,8	high_impact	5,2	neutral	0,83	neutral	0,55	deleterious	4,18	23,8	0,06	0,35	disease	0,91	disease	0,9	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,02	high_impact	3,53	0,35	0,8	16,32	19,7	P	0,66	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8948	8948	T	A	MI.896	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	422	141	L	Q	cTa/cAa	0,13	0,01	0	probably_damaging	1	deleterious	0	neutral	4,02	deleterious	-5,02	deleterious	-5,29	high_impact	4,38	damaging	0,47	damaging	0,15	deleterious	4,39	24,1	0,18	0,65	disease	0,9	disease	0,66	disease	0,67	disease	0,73	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,83	low_impact	-3,6	low_impact	-1,4	high_impact	2,66	0,7	0,9	46,46	8,22	N	0,41	N	0,98	polymorphism	0,61	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15040	15040	C	G	MI.8960	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	294	98	I	M	atC/atG	4,54	0,67	0,01	probably_damaging	1	neutral	0,22	neutral	3,45	neutral	1,79	neutral	-2,36	medium_impact	2,58	neutral	0,81	neutral	0,68	deleterious	2,81	21,4	0,15	0,45	neutral	0,3	disease	0,72	neutral	0,36	neutral	0,37	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,69	low_impact	-3,53	medium_impact	-0,08	medium_impact	1,15	0,57	0,8	16,32	19,7	N	0,34	N	0,78	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15040	15040	C	A	MI.8961	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	294	98	I	M	atC/atA	4,54	0,67	0,01	probably_damaging	1	neutral	0,22	neutral	3,45	neutral	1,79	neutral	-2,36	medium_impact	2,58	neutral	0,81	neutral	0,68	deleterious	3,32	22,9	0,15	0,45	neutral	0,3	disease	0,72	neutral	0,36	neutral	0,37	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,69	low_impact	-3,53	medium_impact	-0,08	medium_impact	1,15	0,57	0,8	16,32	19,7	N	0,34	N	0,78	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15041	15041	G	C	MI.8962	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	295	99	G	R	Ggg/Cgg	-4,86	0	0	probably_damaging	1	neutral	0,36	neutral	3,12	neutral	-1,63	deleterious	-5,81	high_impact	4,82	neutral	0,9	damaging	0,22	deleterious	3,88	23,5	0,03	0,35	disease	0,61	disease	0,94	disease	0,75	disease	0,8	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,09	high_impact	3,18	0,43	0,8	56,32	8,65	P	0,67	P	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15041	15041	G	T	MI.8963	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	295	99	G	W	Ggg/Tgg	-4,86	0	0	probably_damaging	1	neutral	0,17	neutral	3,1	deleterious	-3	deleterious	-6,16	high_impact	4,36	neutral	0,89	damaging	0,24	deleterious	4,34	24	0,04	0,35	disease	0,83	disease	0,94	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,15	high_impact	2,77	0,12	0,8	56,32	8,65	N	0,46	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15042	15042	G	A	MI.8964	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	296	99	G	E	gGg/gAg	5,92	1	0	probably_damaging	1	neutral	0,25	neutral	3,11	neutral	-1,96	deleterious	-5,8	high_impact	5,17	neutral	0,86	neutral	0,3	deleterious	3,85	23,4	0,03	0,35	disease	0,58	disease	0,91	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,04	high_impact	3,5	0,23	0,8	56,32	8,65	P	0,65	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15042	15042	G	C	MI.8965	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	296	99	G	A	gGg/gCg	5,92	1	0	probably_damaging	1	neutral	0,49	neutral	3,28	neutral	0,92	deleterious	-3,53	low_impact	1,55	neutral	0,9	neutral	0,43	deleterious	1,94	15,81	0,09	0,35	neutral	0,21	disease	0,54	neutral	0,33	neutral	0,18	6	deleterious	1	neutral	0,25	neutral	-2	deleterious	0,72	low_impact	-3,53	medium_impact	0,21	medium_impact	0,21	0,42	0,8	56,32	8,65	N	0,53	P	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15042	15042	G	T	MI.8966	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	296	99	G	V	gGg/gTg	5,92	1	0	probably_damaging	1	neutral	0,5	neutral	3,21	neutral	0,84	deleterious	-6,34	high_impact	4,47	neutral	0,91	neutral	0,35	deleterious	3,75	23,3	0,03	0,35	neutral	0,37	disease	0,93	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,22	high_impact	2,87	0,18	0,8	56,32	8,65	P	0,54	P	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15044	15044	C	T	MI.8967	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	298	100	R	W	Cga/Tga	-8,3	0	0	probably_damaging	1	neutral	0,18	neutral	2,44	deleterious	-7,5	deleterious	-6,99	high_impact	4,89	neutral	0,82	damaging	0,2	deleterious	5,18	25,5	0,09	0,35	disease	0,65	disease	0,92	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,14	high_impact	3,25	0,8	0,85	57,37	8,76	P	0,59	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15044	15044	C	G	MI.8968	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	298	100	R	G	Cga/Gga	-8,3	0	0	probably_damaging	1	neutral	0,34	neutral	2,48	deleterious	-5,6	deleterious	-6,11	high_impact	4,29	neutral	0,81	neutral	0,34	deleterious	4	23,6	0,06	0,35	disease	0,78	disease	0,84	disease	0,78	disease	0,68	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,07	high_impact	2,7	0,25	0,8	57,37	8,76	N	0,45	N	0,99	polymorphism	1	0,18	rs879127956	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15045	15045	G	T	MI.8969	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	299	100	R	L	cGa/cTa	2,71	0,98	0	probably_damaging	1	neutral	0,65	neutral	2,47	deleterious	-4,3	deleterious	-6,11	high_impact	5,09	neutral	0,82	damaging	0,27	deleterious	4,06	23,7	0,07	0,35	disease	0,72	disease	0,95	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,37	high_impact	3,43	0,06	0,8	57,37	8,76	P	0,68	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8948	8948	T	G	MI.897	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	422	141	L	R	cTa/cGa	0,13	0,01	0	probably_damaging	1	deleterious	0	neutral	4,05	deleterious	-4,85	deleterious	-5,29	high_impact	4,38	damaging	0,38	damaging	0,13	deleterious	4,23	23,9	0,14	0,65	disease	0,89	disease	0,81	disease	0,77	disease	0,81	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,66	0,51	0,9	46,46	8,22	P	0,63	P	0,99	polymorphism	0,56	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15045	15045	G	A	MI.8970	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	299	100	R	Q	cGa/cAa	2,71	0,98	0	probably_damaging	1	neutral	0,29	neutral	2,57	deleterious	-4,32	deleterious	-3,46	high_impact	4,75	neutral	0,75	damaging	0,23	deleterious	4,27	24	0,16	0,45	disease	0,59	disease	0,84	disease	0,8	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,01	high_impact	3,12	0,72	0,85	57,37	8,76	P	0,79	P	1	polymorphism	1	0,05	.	.	.	.	.	.	COSM1138294	.	.	.	.	.	.	.	.
chrM	15045	15045	G	C	MI.8971	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	299	100	R	P	cGa/cCa	2,71	0,98	0	probably_damaging	1	neutral	0,2	neutral	2,46	deleterious	-5,67	deleterious	-6,11	high_impact	5,44	neutral	0,82	damaging	0,2	deleterious	4,19	23,8	0,03	0,35	disease	0,82	disease	0,9	disease	0,81	disease	0,68	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,1	high_impact	3,75	0,17	0,8	57,37	8,76	P	0,7	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15047	15047	G	C	MI.8972	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	301	101	G	R	Ggc/Cgc	0,18	0,96	0,01	probably_damaging	1	neutral	0,37	neutral	3,12	deleterious	-3,29	deleterious	-6,98	high_impact	5,39	neutral	0,9	damaging	0,22	deleterious	3,94	23,5	0,02	0,35	disease	0,94	disease	0,92	disease	0,76	disease	0,6	2	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,92	low_impact	-3,53	medium_impact	0,1	high_impact	3,7	0,5	0,8	31,58	9,28	P	0,65	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15047	15047	G	A	MI.8973	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	301	101	G	S	Ggc/Agc	0,18	0,96	0,01	possibly_damaging	0,48	neutral	0,41	neutral	3,14	neutral	-2,32	deleterious	-5,21	medium_impact	3,48	neutral	0,9	neutral	0,44	deleterious	4,09	23,7	0,05	0,35	disease	0,78	disease	0,85	disease	0,6	disease	0,66	3	neutral	0,56	neutral	0,47	NA	0	deleterious	0,52	medium_impact	-0,7	medium_impact	0,14	medium_impact	1,97	0,6	0,8	31,58	9,28	N	0,47	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15047	15047	G	T	MI.8974	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	301	101	G	C	Ggc/Tgc	0,18	0,96	0,01	probably_damaging	1	neutral	0,17	neutral	3,07	deleterious	-3,94	deleterious	-7,86	high_impact	5,05	neutral	0,91	damaging	0,22	deleterious	4,16	23,8	0,03	0,35	disease	0,95	disease	0,92	disease	0,7	disease	0,61	2	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,15	high_impact	3,39	0,14	0,8	31,58	9,28	P	0,62	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15048	15048	G	T	MI.8975	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	302	101	G	V	gGc/gTc	5	1	0	probably_damaging	1	neutral	0,5	neutral	3,21	neutral	0,45	deleterious	-7,86	high_impact	5,39	neutral	0,91	neutral	0,36	deleterious	3,73	23,3	0,03	0,35	disease	0,91	disease	0,92	disease	0,69	disease	0,62	2	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,22	high_impact	3,7	0,15	0,8	31,58	9,28	P	0,67	P	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15048	15048	G	C	MI.8976	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	302	101	G	A	gGc/gCc	5	1	0	possibly_damaging	0,66	neutral	0,5	neutral	3,15	neutral	-1,71	deleterious	-5,23	high_impact	4,04	neutral	0,91	neutral	0,42	deleterious	3,04	22,4	0,05	0,35	disease	0,77	disease	0,78	disease	0,68	disease	0,67	3	neutral	0,64	neutral	0,42	deleterious	1	deleterious	0,77	medium_impact	-1	medium_impact	0,22	high_impact	2,48	0,4	0,8	31,58	9,28	P	0,58	P	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15048	15048	G	A	MI.8977	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	302	101	G	D	gGc/gAc	5	1	0	probably_damaging	0,99	neutral	0,2	neutral	3,11	deleterious	-3,97	deleterious	-6,1	high_impact	5,39	neutral	0,86	damaging	0,28	deleterious	3,86	23,5	0,03	0,35	disease	0,9	disease	0,92	disease	0,79	disease	0,63	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-2,59	medium_impact	-0,1	high_impact	3,7	0,11	0,8	31,58	9,28	P	0,71	P	1	polymorphism	1	0,18	.	.	.	.	.	.	COSM1138296	.	.	.	.	.	.	.	.
chrM	15050	15050	C	G	MI.8978	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	304	102	L	V	Cta/Gta	-20	0	0	benign	0,32	neutral	0,5	neutral	3,1	neutral	-0,52	neutral	-1,95	medium_impact	3,35	neutral	0,97	neutral	0,74	deleterious	2,94	22	0,19	0,45	disease	0,63	disease	0,63	neutral	0,48	neutral	0,34	3	neutral	0,41	deleterious	0,59	neutral	-3	deleterious	0,47	medium_impact	-0,43	medium_impact	0,22	medium_impact	1,85	0,49	0,8	17,63	25,1	N	0,29	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15050	15050	C	A	MI.8979	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	304	102	L	M	Cta/Ata	-20	0	0	benign	0,32	neutral	0,22	neutral	3,01	neutral	-1,72	neutral	-1,34	medium_impact	2,09	neutral	0,96	neutral	0,88	deleterious	2,37	18,62	0,19	0,45	neutral	0,48	neutral	0,41	neutral	0,26	neutral	0,42	2	neutral	0,74	neutral	0,45	neutral	-3	neutral	0,35	medium_impact	-0,43	medium_impact	-0,08	medium_impact	0,7	0,52	0,8	17,63	25,1	N	0,43	N	0,52	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8948	8948	T	C	MI.898	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	422	141	L	P	cTa/cCa	0,13	0,01	0	probably_damaging	1	deleterious	0	neutral	4	deleterious	-5,42	deleterious	-6,18	high_impact	4,04	damaging	0,29	damaging	0,15	deleterious	3,98	23,6	0,19	0,65	disease	0,92	disease	0,75	disease	0,77	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,36	0,74	0,9	46,46	8,22	P	0,8	P	1	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15051	15051	T	G	MI.8980	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	305	102	L	R	cTa/cGa	-4,86	0	0	probably_damaging	0,94	neutral	0,35	neutral	2,96	deleterious	-3,63	deleterious	-4,9	high_impact	5,01	neutral	0,94	neutral	0,47	deleterious	4,13	23,8	0,01	0,35	disease	0,94	disease	0,88	disease	0,72	disease	0,67	3	neutral	0,94	neutral	0,21	deleterious	2	deleterious	0,89	low_impact	-1,85	medium_impact	0,08	high_impact	3,36	0,11	0,8	17,63	25,1	P	0,7	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15051	15051	T	A	MI.8981	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	305	102	L	Q	cTa/cAa	-4,86	0	0	probably_damaging	0,94	neutral	0,29	neutral	2,95	deleterious	-3,79	deleterious	-4,85	high_impact	5,01	neutral	0,94	neutral	0,51	deleterious	4	23,6	0,02	0,35	disease	0,93	disease	0,77	disease	0,6	disease	0,68	4	neutral	0,95	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-1,85	medium_impact	0,01	high_impact	3,36	0,21	0,8	17,63	25,1	P	0,65	P	0,89	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15051	15051	T	C	MI.8982	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	305	102	L	P	cTa/cCa	-4,86	0	0	probably_damaging	0,99	neutral	0,2	neutral	2,95	deleterious	-4,19	deleterious	-5,64	high_impact	5,01	neutral	0,93	neutral	0,35	deleterious	3,87	23,5	0,01	0,35	disease	0,95	disease	0,86	disease	0,6	disease	0,67	3	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,91	low_impact	-2,59	medium_impact	-0,1	high_impact	3,36	0,18	0,8	17,63	25,1	P	0,64	P	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15053	15053	T	C	MI.8983	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	307	103	Y	H	Tat/Cat	-16,1	0	0	probably_damaging	1	neutral	0,47	neutral	3,01	deleterious	-4,06	deleterious	-4,39	high_impact	5,04	neutral	0,89	damaging	0,08	deleterious	3,43	23	0,07	0,35	disease	0,83	disease	0,85	disease	0,82	disease	0,68	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,19	high_impact	3,38	0,15	0,8	58,95	8,74	P	0,73	P	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15053	15053	T	G	MI.8984	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	307	103	Y	D	Tat/Gat	-16,1	0	0	probably_damaging	1	neutral	0,17	neutral	3	deleterious	-4,75	deleterious	-8,77	high_impact	5,04	neutral	0,83	damaging	0,07	deleterious	3,86	23,5	0,03	0,35	disease	0,95	disease	0,91	disease	0,82	disease	0,65	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,15	high_impact	3,38	0,12	0,8	58,95	8,74	P	0,63	P	1	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15053	15053	T	A	MI.8985	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	307	103	Y	N	Tat/Aat	-16,1	0	0	probably_damaging	1	neutral	0,29	neutral	3,02	deleterious	-3,48	deleterious	-7,89	high_impact	4,11	neutral	0,85	damaging	0,09	deleterious	3,93	23,5	0,05	0,35	disease	0,66	disease	0,9	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,01	high_impact	2,54	0,12	0,8	58,95	8,74	N	0,4	N	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15054	15054	A	T	MI.8986	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	308	103	Y	F	tAt/tTt	7,3	1	0	probably_damaging	1	neutral	0,61	neutral	3,41	neutral	0,61	deleterious	-3,49	medium_impact	2,92	neutral	0,91	damaging	0,08	deleterious	2,87	21,7	0,14	0,4	neutral	0,47	disease	0,86	disease	0,63	disease	0,67	3	deleterious	1	neutral	0,31	deleterious	1	deleterious	0,83	low_impact	-3,53	medium_impact	0,33	medium_impact	1,46	0,47	0,8	58,95	8,74	N	0,47	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15054	15054	A	G	MI.8987	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	308	103	Y	C	tAt/tGt	7,3	1	0	probably_damaging	1	neutral	0,15	neutral	3,02	deleterious	-3,94	deleterious	-7,89	high_impact	5,04	neutral	0,85	damaging	0,05	deleterious	3,37	22,9	0,03	0,35	disease	0,96	disease	0,9	disease	0,78	disease	0,66	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,19	high_impact	3,38	0,16	0,8	58,95	8,74	P	0,69	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15054	15054	A	C	MI.8988	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	308	103	Y	S	tAt/tCt	7,3	1	0	probably_damaging	1	neutral	0,36	neutral	3,05	neutral	-2,49	deleterious	-7,89	high_impact	5,04	neutral	0,88	damaging	0,09	deleterious	3,48	23,1	0,04	0,35	disease	0,9	disease	0,87	disease	0,74	disease	0,61	2	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,09	high_impact	3,38	0,13	0,8	58,95	8,74	P	0,73	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15056	15056	T	C	MI.8989	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	310	104	Y	H	Tac/Cac	-3,03	0	0	probably_damaging	1	neutral	0,36	neutral	3,02	deleterious	-3,29	deleterious	-4,36	high_impact	4,53	neutral	0,9	damaging	0,08	deleterious	3,51	23,1	0,08	0,35	disease	0,64	disease	0,84	disease	0,8	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,09	high_impact	2,92	0,33	0,8	58,16	8,8	N	0,55	P	0,98	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8950	8950	G	C	MI.899	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	424	142	V	L	Gtt/Ctt	-2,19	0	0,01	benign	0,01	neutral	0,2	neutral	4,38	neutral	-0,04	neutral	-1,66	medium_impact	2,79	neutral	0,8	neutral	0,53	neutral	1,64	14,06	0,36	0,65	neutral	0,42	disease	0,59	disease	0,58	disease	0,67	3	neutral	0,8	deleterious	0,6	neutral	-3	neutral	0,18	medium_impact	1,14	medium_impact	-0,05	medium_impact	1,29	0,57	0,9	11,95	13,75	N	0,36	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15056	15056	T	A	MI.8990	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	310	104	Y	N	Tac/Aac	-3,03	0	0	probably_damaging	1	neutral	0,19	neutral	3,02	neutral	-2,81	deleterious	-7,87	high_impact	4,22	neutral	0,86	damaging	0,09	deleterious	4,12	23,8	0,04	0,35	disease	0,92	disease	0,9	disease	0,83	disease	0,65	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,12	high_impact	2,64	0,24	0,8	58,16	8,8	N	0,47	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15056	15056	T	G	MI.8991	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	310	104	Y	D	Tac/Gac	-3,03	0	0	probably_damaging	1	neutral	0,12	neutral	3,03	neutral	-2,87	deleterious	-8,74	high_impact	5,42	neutral	0,84	damaging	0,07	deleterious	3,87	23,5	0,03	0,35	disease	0,96	disease	0,9	disease	0,87	disease	0,69	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,25	high_impact	3,73	0,15	0,8	58,16	8,8	P	0,67	P	1	disease_causing	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15057	15057	A	T	MI.8992	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	311	104	Y	F	tAc/tTc	7,3	1	0	probably_damaging	1	neutral	0,42	neutral	3,09	neutral	-2,17	deleterious	-3,47	medium_impact	3,25	neutral	0,91	damaging	0,08	deleterious	3,06	22,4	0,14	0,4	neutral	0,42	disease	0,84	disease	0,74	disease	0,57	1	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,82	low_impact	-3,53	medium_impact	0,15	medium_impact	1,76	0,56	0,8	58,16	8,8	N	0,57	P	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15057	15057	A	G	MI.8993	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	311	104	Y	C	tAc/tGc	7,3	1	0	probably_damaging	1	neutral	0,1	neutral	3,02	deleterious	-4,39	deleterious	-7,88	high_impact	5,08	neutral	0,86	damaging	0,05	deleterious	3,5	23,1	0,03	0,35	disease	0,96	disease	0,9	disease	0,84	disease	0,68	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,3	high_impact	3,42	0,3	0,8	58,16	8,8	P	0,69	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15057	15057	A	C	MI.8994	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	311	104	Y	S	tAc/tCc	7,3	1	0	probably_damaging	1	neutral	0,3	neutral	3,05	neutral	-1,81	deleterious	-7,86	high_impact	5,08	neutral	0,88	damaging	0,09	deleterious	3,62	23,2	0,04	0,35	disease	0,91	disease	0,86	disease	0,8	disease	0,66	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,02	high_impact	3,42	0,3	0,8	58,16	8,8	P	0,76	P	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15059	15059	G	C	MI.8995	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	313	105	G	R	Gga/Cga	-4,4	0	0	probably_damaging	1	neutral	0,34	neutral	2,73	deleterious	-3,75	deleterious	-6,76	high_impact	4,67	neutral	0,83	damaging	0,04	deleterious	3,94	23,5	0,03	0,35	disease	0,76	disease	0,9	disease	0,82	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0,07	high_impact	3,05	0,53	0,8	58,42	8,78	P	0,58	P	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15059	15059	G	T	MI.8996	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	313	105	G	W	Gga/Tga	-4,4	0	0	probably_damaging	1	neutral	0,19	neutral	2,67	deleterious	-7,87	deleterious	-6,86	high_impact	5,22	neutral	0,84	damaging	0,05	deleterious	4,4	24,1	0,03	0,35	disease	0,95	disease	0,93	disease	0,78	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,12	high_impact	3,55	0,17	0,8	58,42	8,78	P	0,6	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15060	15060	G	A	MI.8997	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	314	105	G	E	gGa/gAa	5,92	1	0	probably_damaging	1	neutral	0,27	neutral	2,76	deleterious	-3,46	deleterious	-6,73	high_impact	4,88	neutral	0,82	damaging	0,05	deleterious	3,78	23,4	0,02	0,35	disease	0,68	disease	0,9	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,01	high_impact	3,24	0,29	0,8	58,42	8,78	P	0,74	P	1	polymorphism	1	0,17	rs1057516072	Likely pathogenic|Likely pathogenic	Bilateral_lesions_of_basal_ganglia|Seizure_Disorders	RCV000408920.1|RCV000408920.1	MedGen|MedGen	.	.	.	.	.	.	.	.	.	.
chrM	15060	15060	G	T	MI.8998	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	314	105	G	V	gGa/gTa	5,92	1	0	probably_damaging	1	neutral	0,49	neutral	2,7	deleterious	-4,77	deleterious	-7,65	high_impact	5,22	neutral	0,84	damaging	0,07	deleterious	3,76	23,3	0,03	0,35	disease	0,71	disease	0,91	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,21	high_impact	3,55	0,19	0,8	58,42	8,78	P	0,71	P	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15060	15060	G	C	MI.8999	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	314	105	G	A	gGa/gCa	5,92	1	0	probably_damaging	1	neutral	0,49	neutral	2,76	deleterious	-3,33	deleterious	-5,01	high_impact	4,42	neutral	0,84	damaging	0,1	deleterious	3,07	22,4	0,04	0,35	neutral	0,42	disease	0,8	disease	0,71	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,21	high_impact	2,82	0,51	0,8	58,42	8,78	N	0,5	N	0,83	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8530	8530	A	T	MI.9	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	4	2	N	Y	Aac/Tac	7,3	1	0	probably_damaging	0,99	deleterious	0,04	neutral	4,61	neutral	-1,66	deleterious	-4,59	medium_impact	2,6	neutral	0,89	neutral	0,44	deleterious	4,16	23,8	0,46	0,65	neutral	0,48	neutral	0,44	neutral	0,26	neutral	0,46	1	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,68	low_impact	-2,65	medium_impact	-0,49	medium_impact	1,13	0,37	0,9	41,59	7,23	P	0,63	P	1	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8567	8567	T	C	MI.90	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	41	14	I	T	aTc/aCc	-4,27	0	0	benign	0,39	neutral	0,25	neutral	4,6	neutral	-0,76	deleterious	-2,6	neutral_impact	0,08	neutral	0,96	neutral	0,83	deleterious	4,14	23,8	0,54	0,65	neutral	0,32	neutral	0,3	neutral	0,44	neutral	0,45	1	neutral	0,71	neutral	0,43	neutral	-6	neutral	0,37	medium_impact	-0,57	medium_impact	0,02	low_impact	-1,03	0,54	0,9	13,72	12,42	N	0,46	N	0,47	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8950	8950	G	A	MI.900	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	424	142	V	I	Gtt/Att	-2,19	0	0,01	benign	0	neutral	0,63	neutral	4,21	neutral	-1	neutral	0,12	neutral_impact	0,08	neutral	0,87	neutral	0,97	neutral	-0,97	0,02	0,4	0,65	neutral	0,5	neutral	0,04	neutral	0,3	neutral	0,14	7	neutral	0,37	deleterious	0,82	neutral	-6	neutral	0,11	high_impact	2,09	medium_impact	0,42	low_impact	-1,03	0,76	0,9	11,95	13,75	N	0,47	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	COSM1155686	CPD	29,93	G8950A	LDYT	+	-	Reported	2
chrM	15062	15062	T	G	MI.9000	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	316	106	S	A	Tca/Gca	-9,68	0	0	probably_damaging	0,99	neutral	0,49	neutral	3,39	neutral	0,01	deleterious	-2,65	high_impact	4,21	neutral	0,88	damaging	0,12	deleterious	3,31	22,9	0,14	0,4	disease	0,51	disease	0,72	disease	0,73	disease	0,69	4	deleterious	0,99	neutral	0,25	deleterious	2	deleterious	0,8	low_impact	-2,59	medium_impact	0,21	high_impact	2,63	0,47	0,8	57,89	8,61	N	0,32	N	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15062	15062	T	C	MI.9001	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	316	106	S	P	Tca/Cca	-9,68	0	0	probably_damaging	1	neutral	0,2	neutral	2,96	deleterious	-4,49	deleterious	-4,42	high_impact	4,64	neutral	0,89	damaging	0,06	deleterious	3,81	23,4	0,04	0,35	disease	0,87	disease	0,85	disease	0,74	disease	0,62	2	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,1	high_impact	3,02	0,35	0,8	57,89	8,61	N	0,57	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15062	15062	T	A	MI.9002	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	316	106	S	T	Tca/Aca	-9,68	0	0	probably_damaging	0,99	neutral	0,39	neutral	3	neutral	-2,74	deleterious	-2,65	high_impact	4,35	neutral	0,87	damaging	0,08	deleterious	2,12	16,99	0,13	0,4	disease	0,74	disease	0,77	disease	0,73	disease	0,69	4	deleterious	0,99	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-2,59	medium_impact	0,12	high_impact	2,76	0,62	0,8	57,89	8,61	N	0,38	N	0,7	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15063	15063	C	T	MI.9003	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	317	106	S	L	tCa/tTa	7,3	1	0	probably_damaging	1	neutral	0,64	neutral	3	deleterious	-3,05	deleterious	-5,3	high_impact	4,41	neutral	0,87	damaging	0,05	deleterious	4,53	24,3	0,03	0,35	disease	0,9	disease	0,91	disease	0,71	disease	0,61	2	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,36	high_impact	2,81	0,49	0,8	57,89	8,61	P	0,56	P	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15063	15063	C	G	MI.9004	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	317	106	S	W	tCa/tGa	7,3	1	0	probably_damaging	1	neutral	0,19	neutral	2,95	deleterious	-5,82	deleterious	-6,19	high_impact	5,45	neutral	0,89	damaging	0,07	deleterious	4,26	23,9	0,04	0,35	disease	0,98	disease	0,92	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,12	high_impact	3,76	0,16	0,8	57,89	8,61	P	0,71	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15065	15065	T	C	MI.9005	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	319	107	F	L	Ttt/Ctt	-15,18	0	0	probably_damaging	0,99	neutral	0,63	neutral	2,69	deleterious	-3,36	deleterious	-3,78	high_impact	3,56	neutral	0,88	damaging	0,23	deleterious	2,41	18,87	0,12	0,4	disease	0,55	disease	0,71	disease	0,69	disease	0,71	4	deleterious	0,99	neutral	0,32	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	0,35	high_impact	2,04	0,66	0,8	22,89	29,41	N	0,23	N	0,7	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15065	15065	T	A	MI.9006	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	319	107	F	I	Ttt/Att	-15,18	0	0	probably_damaging	1	neutral	0,39	neutral	2,67	deleterious	-4,76	deleterious	-3,78	high_impact	3,56	neutral	0,87	damaging	0,27	deleterious	4,11	23,7	0,1	0,4	disease	0,71	disease	0,68	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,12	high_impact	2,04	0,42	0,8	22,89	29,41	N	0,33	N	0,61	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15065	15065	T	G	MI.9007	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	319	107	F	V	Ttt/Gtt	-15,18	0	0	probably_damaging	1	neutral	0,49	neutral	2,67	deleterious	-4,64	deleterious	-3,91	high_impact	4,11	neutral	0,88	neutral	0,3	deleterious	3,77	23,4	0,06	0,35	disease	0,69	disease	0,79	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,21	high_impact	2,54	0,31	0,8	22,89	29,41	N	0,33	N	0,71	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15066	15066	T	C	MI.9008	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	320	107	F	S	tTt/tCt	7,3	1	0	probably_damaging	1	neutral	0,42	neutral	2,67	deleterious	-5,22	deleterious	-4,77	medium_impact	2,67	neutral	0,86	damaging	0,23	deleterious	3,99	23,6	0,03	0,35	disease	0,75	disease	0,72	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,87	low_impact	-3,53	medium_impact	0,15	medium_impact	1,23	0,18	0,8	22,89	29,41	N	0,51	P	0,82	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15066	15066	T	A	MI.9009	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	320	107	F	Y	tTt/tAt	7,3	1	0	probably_damaging	0,99	neutral	1	neutral	3,88	neutral	2,88	neutral	2,63	neutral_impact	-1,03	neutral	0,92	neutral	0,87	deleterious	0,03	2,83	0,12	0,4	neutral	0,27	neutral	0,07	neutral	0,28	neutral	0,17	7	deleterious	0,99	deleterious	0,51	neutral	-2	deleterious	0,68	low_impact	-2,59	high_impact	1,85	low_impact	-2,13	0,59	0,8	22,89	29,41	P	0,53	P	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8950	8950	G	T	MI.901	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	424	142	V	F	Gtt/Ttt	-2,19	0	0,01	benign	0,13	deleterious	0,04	neutral	4,13	neutral	-1,67	deleterious	-3,43	medium_impact	2,54	neutral	0,79	neutral	0,5	deleterious	2,02	16,32	0,17	0,65	disease	0,63	disease	0,77	disease	0,65	disease	0,71	4	neutral	0,96	neutral	0,46	deleterious	1	neutral	0,31	medium_impact	0,03	medium_impact	-0,49	medium_impact	1,08	0,52	0,9	11,95	13,75	N	0,3	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15066	15066	T	G	MI.9010	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	320	107	F	C	tTt/tGt	7,3	1	0	probably_damaging	1	neutral	0,17	neutral	2,66	deleterious	-6,71	deleterious	-4,79	high_impact	3,77	neutral	0,91	damaging	0,23	deleterious	4,04	23,7	0,04	0,35	disease	0,89	disease	0,83	disease	0,73	disease	0,66	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,15	high_impact	2,23	0,15	0,8	22,89	29,41	P	0,57	P	0,85	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15067	15067	T	G	MI.9011	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	321	107	F	L	ttT/ttG	2,94	0,98	0,1	probably_damaging	0,99	neutral	0,63	neutral	2,69	deleterious	-3,36	deleterious	-3,78	high_impact	3,56	neutral	0,88	damaging	0,23	deleterious	2,78	21,3	0,12	0,4	disease	0,55	disease	0,71	disease	0,69	disease	0,71	4	deleterious	0,99	neutral	0,32	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	0,35	high_impact	2,04	0,66	0,8	22,89	29,41	N	0,47	N	0,7	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15067	15067	T	A	MI.9012	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	321	107	F	L	ttT/ttA	2,94	0,98	0,1	probably_damaging	0,99	neutral	0,63	neutral	2,69	deleterious	-3,36	deleterious	-3,78	high_impact	3,56	neutral	0,88	damaging	0,23	deleterious	2,91	21,9	0,12	0,4	disease	0,55	disease	0,71	disease	0,69	disease	0,71	4	deleterious	0,99	neutral	0,32	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	0,35	high_impact	2,04	0,66	0,8	22,89	29,41	N	0,48	N	0,7	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15068	15068	C	T	MI.9013	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	322	108	L	F	Ctc/Ttc	-1,19	0	0	probably_damaging	0,9	neutral	0,49	neutral	3,09	neutral	-2,61	deleterious	-2,86	medium_impact	2,88	neutral	0,95	damaging	0,25	deleterious	3,86	23,5	0,13	0,4	disease	0,58	disease	0,73	neutral	0,21	neutral	0,36	3	neutral	0,9	neutral	0,3	deleterious	1	deleterious	0,72	low_impact	-1,62	medium_impact	0,21	medium_impact	1,42	0,5	0,8	21,32	23,47	N	0,28	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15068	15068	C	G	MI.9014	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	322	108	L	V	Ctc/Gtc	-1,19	0	0	benign	0,22	neutral	0,34	neutral	3,11	neutral	-1,17	neutral	-1,78	medium_impact	2,64	neutral	0,98	neutral	0,6	deleterious	1,94	15,81	0,18	0,45	neutral	0,37	disease	0,61	neutral	0,33	neutral	0,21	6	neutral	0,59	deleterious	0,56	neutral	-3	neutral	0,27	medium_impact	-0,22	medium_impact	0,07	medium_impact	1,2	0,45	0,8	21,32	23,47	N	0,38	N	0,07	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15068	15068	C	A	MI.9015	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	322	108	L	I	Ctc/Atc	-1,19	0	0	possibly_damaging	0,44	neutral	0,3	neutral	3,1	neutral	-1,8	neutral	-1,23	medium_impact	2,54	neutral	0,96	neutral	0,71	deleterious	2,73	21	0,2	0,45	neutral	0,44	disease	0,55	neutral	0,19	neutral	0,2	6	neutral	0,66	neutral	0,43	NA	0	neutral	0,32	medium_impact	-0,63	medium_impact	0,02	medium_impact	1,11	0,54	0,8	21,32	23,47	N	0,48	N	0,22	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15069	15069	T	A	MI.9016	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	323	108	L	H	cTc/cAc	-1,42	0	0	probably_damaging	0,96	neutral	0,31	neutral	3,13	neutral	-1,25	deleterious	-5,05	medium_impact	3,41	neutral	0,93	damaging	0,21	deleterious	4,02	23,6	0,03	0,35	disease	0,52	disease	0,77	neutral	0,25	neutral	0,4	2	neutral	0,97	neutral	0,18	deleterious	1	deleterious	0,75	low_impact	-2,02	medium_impact	0,03	medium_impact	1,9	0,24	0,8	21,32	23,47	N	0,38	N	0,6	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15069	15069	T	C	MI.9017	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	323	108	L	P	cTc/cCc	-1,42	0	0	probably_damaging	0,95	neutral	0,11	neutral	3,1	neutral	-1,73	deleterious	-5	high_impact	4,38	neutral	0,94	damaging	0,16	deleterious	3,8	23,4	0,01	0,35	disease	0,56	disease	0,88	disease	0,51	disease	0,63	3	deleterious	0,98	neutral	0,08	deleterious	2	deleterious	0,82	low_impact	-1,92	medium_impact	-0,27	high_impact	2,78	0,08	0,8	21,32	23,47	N	0,48	N	0,67	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15069	15069	T	G	MI.9018	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	323	108	L	R	cTc/cGc	-1,42	0	0	possibly_damaging	0,87	neutral	0,18	neutral	3,33	neutral	2,75	deleterious	-4,24	medium_impact	2,77	neutral	0,94	damaging	0,18	deleterious	4,05	23,7	0,02	0,35	neutral	0,16	disease	0,88	neutral	0,32	disease	0,66	3	neutral	0,93	neutral	0,16	NA	0	deleterious	0,68	low_impact	-1,5	medium_impact	-0,14	medium_impact	1,32	0,2	0,8	21,32	23,47	N	0,36	N	0,52	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15071	15071	T	A	MI.9019	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	325	109	Y	N	Tac/Aac	-10,6	0	0,01	possibly_damaging	0,71	neutral	0,29	neutral	3,12	deleterious	-3,73	deleterious	-5,35	low_impact	0,94	neutral	0,83	neutral	0,54	deleterious	2,72	20,9	0,09	0,35	neutral	0,42	disease	0,83	neutral	0,36	neutral	0,19	6	neutral	0,78	neutral	0,29	neutral	-3	deleterious	0,51	low_impact	-1,09	medium_impact	0,01	medium_impact	-0,34	0,3	0,8	25,53	33,41	N	0,33	N	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8951	8951	T	A	MI.902	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	425	142	V	D	gTt/gAt	1,29	0,65	0,01	benign	0,38	deleterious	0	neutral	4	deleterious	-5,86	deleterious	-5,7	high_impact	3,83	neutral	0,79	neutral	0,44	deleterious	2,91	21,9	0,07	0,65	disease	0,93	disease	0,79	disease	0,74	disease	0,83	7	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,55	medium_impact	-0,55	low_impact	-1,4	high_impact	2,19	0,54	0,9	11,95	13,75	N	0,33	N	0,99	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15071	15071	T	G	MI.9020	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	325	109	Y	D	Tac/Gac	-10,6	0	0,01	possibly_damaging	0,78	neutral	0,17	neutral	3,11	deleterious	-4,44	deleterious	-6,41	high_impact	3,81	neutral	0,79	neutral	0,38	deleterious	3,78	23,4	0,05	0,35	neutral	0,45	disease	0,91	disease	0,54	disease	0,64	3	neutral	0,89	neutral	0,2	deleterious	1	deleterious	0,62	low_impact	-1,24	medium_impact	-0,15	high_impact	2,27	0,26	0,8	25,53	33,41	N	0,38	N	0,68	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15071	15071	T	C	MI.9021	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	325	109	Y	H	Tac/Cac	-10,6	0	0,01	benign	0,04	neutral	0,46	neutral	3,09	deleterious	-3,91	deleterious	-3,23	medium_impact	2,91	neutral	0,78	neutral	0,66	deleterious	3,37	22,9	0,13	0,4	neutral	0,49	disease	0,81	neutral	0,32	neutral	0,44	1	neutral	0,5	deleterious	0,71	neutral	-3	neutral	0,26	medium_impact	0,56	medium_impact	0,18	medium_impact	1,45	0,34	0,8	25,53	33,41	N	0,28	N	0,06	polymorphism	1	0,03	rs199999794	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15072	15072	A	T	MI.9022	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	326	109	Y	F	tAc/tTc	0,18	0	0	possibly_damaging	0,55	neutral	0,7	neutral	3,09	neutral	-0,42	neutral	-1,82	neutral_impact	0,52	neutral	0,94	neutral	0,96	deleterious	0,66	8,54	0,17	0,45	neutral	0,22	neutral	0,43	neutral	0,24	neutral	0,41	2	neutral	0,46	deleterious	0,58	neutral	-3	neutral	0,3	medium_impact	-0,81	medium_impact	0,42	medium_impact	-0,72	0,37	0,8	25,53	33,41	N	0,32	N	0,04	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15072	15072	A	G	MI.9023	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	326	109	Y	C	tAc/tGc	0,18	0	0	benign	0,06	neutral	0,15	neutral	3,07	deleterious	-4,12	deleterious	-5,74	high_impact	3,81	neutral	0,74	neutral	0,42	deleterious	3,47	23	0,04	0,35	disease	0,66	disease	0,92	neutral	0,5	disease	0,61	2	neutral	0,84	deleterious	0,55	neutral	-2	neutral	0,29	medium_impact	0,38	medium_impact	-0,19	high_impact	2,27	0,13	0,8	25,53	33,41	N	0,41	N	0,59	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15072	15072	A	C	MI.9024	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	326	109	Y	S	tAc/tCc	0,18	0	0	possibly_damaging	0,67	neutral	0,4	neutral	3,13	neutral	-2,65	deleterious	-5,48	medium_impact	2,42	neutral	0,92	neutral	0,85	deleterious	3,53	23,1	0,06	0,35	neutral	0,17	disease	0,85	neutral	0,47	neutral	0,2	6	neutral	0,69	neutral	0,37	NA	0	deleterious	0,51	low_impact	-1,02	medium_impact	0,13	medium_impact	1	0,42	0,8	25,53	33,41	N	0,37	N	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15074	15074	T	C	MI.9025	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	328	110	S	P	Tca/Cca	-5,78	0	0	benign	0,01	neutral	0,21	neutral	3,49	neutral	3,22	neutral	-1,15	neutral_impact	-0,12	neutral	0,96	neutral	0,78	deleterious	2,44	19,08	0,12	0,4	neutral	0,19	disease	0,88	neutral	0,27	neutral	0,46	1	neutral	0,79	deleterious	0,6	neutral	-6	neutral	0,19	medium_impact	1,13	medium_impact	-0,09	low_impact	-1,3	0,13	0,8	20	24,36	N	0,33	N	0,27	polymorphism	1	0,02	rs201169089	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15074	15074	T	A	MI.9026	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	328	110	S	T	Tca/Aca	-5,78	0	0	benign	0,3	neutral	0,4	neutral	3,17	neutral	-0,32	neutral	-0,47	neutral_impact	-0,82	neutral	0,97	neutral	0,96	deleterious	0,43	6,88	0,37	0,5	neutral	0,26	neutral	0,33	neutral	0,12	neutral	0,44	1	neutral	0,52	deleterious	0,55	neutral	-6	neutral	0,13	medium_impact	-0,39	medium_impact	0,13	low_impact	-1,94	0,48	0,8	20	24,36	N	0,48	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15074	15074	T	G	MI.9027	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	328	110	S	A	Tca/Gca	-5,78	0	0	benign	0,09	neutral	0,51	neutral	3,18	neutral	0,03	neutral	-0,8	low_impact	1,31	neutral	0,98	neutral	0,69	deleterious	0,26	5,3	0,37	0,5	neutral	0,25	neutral	0,49	neutral	0,23	neutral	0,46	1	neutral	0,42	deleterious	0,71	neutral	-6	neutral	0,15	medium_impact	0,21	medium_impact	0,23	medium_impact	0	0,2	0,8	20	24,36	N	0,41	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15075	15075	C	G	MI.9028	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	329	110	S	W	tCa/tGa	-1,88	0	0	possibly_damaging	0,89	neutral	0,19	neutral	3,13	deleterious	-4,08	deleterious	-2,5	low_impact	1,77	neutral	0,95	neutral	0,44	deleterious	3,02	22,3	0,08	0,35	disease	0,75	disease	0,89	neutral	0,45	disease	0,64	3	neutral	0,93	neutral	0,15	neutral	-3	deleterious	0,71	low_impact	-1,58	medium_impact	-0,12	medium_impact	0,41	0,14	0,8	20	24,36	N	0,38	N	0,19	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15075	15075	C	T	MI.9029	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	329	110	S	L	tCa/tTa	-1,88	0	0	benign	0,01	neutral	0,65	neutral	3,16	neutral	-0,58	neutral	-1,21	neutral_impact	-0,76	neutral	0,98	neutral	0,96	deleterious	1,88	15,48	0,15	0,4	neutral	0,14	disease	0,7	neutral	0,26	neutral	0,19	6	neutral	0,34	deleterious	0,82	neutral	-6	neutral	0,13	medium_impact	1,13	medium_impact	0,37	low_impact	-1,88	0,35	0,8	20	24,36	N	0,32	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8951	8951	T	C	MI.903	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	425	142	V	A	gTt/gCt	1,29	0,65	0,01	benign	0,05	deleterious	0	neutral	4,08	neutral	-2,33	deleterious	-3,51	medium_impact	2,62	neutral	0,8	neutral	0,64	neutral	1,73	14,6	0,29	0,65	disease	0,66	neutral	0,4	disease	0,6	disease	0,66	3	deleterious	1	deleterious	0,48	deleterious	1	neutral	0,22	medium_impact	0,46	low_impact	-1,4	medium_impact	1,15	0,3	0,9	11,95	13,75	N	0,34	N	0,88	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15077	15077	G	A	MI.9030	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	331	111	E	K	Gaa/Aaa	0,64	0,17	0,01	probably_damaging	1	neutral	0,32	neutral	3,16	neutral	-0,19	deleterious	-2,86	low_impact	1,21	neutral	0,98	neutral	0,55	deleterious	4,04	23,7	0,14	0,4	neutral	0,27	disease	0,85	neutral	0,46	neutral	0,18	7	deleterious	1	neutral	0,16	neutral	-2	deleterious	0,81	low_impact	-3,53	medium_impact	0,05	medium_impact	-0,1	0,64	0,8	23,95	17,94	N	0,45	N	1	polymorphism	1	0,03	rs201943501	.	.	.	.	.	COSM1497292	CPD	5,35	G15077A	DEAF	+	-	Reported	2
chrM	15077	15077	G	C	MI.9031	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	331	111	E	Q	Gaa/Caa	0,64	0,17	0,01	probably_damaging	1	neutral	0,29	neutral	3,13	neutral	-0,92	neutral	-2,34	medium_impact	3,25	neutral	0,92	neutral	0,48	deleterious	3,03	22,3	0,36	0,5	neutral	0,41	disease	0,73	disease	0,58	disease	0,52	0	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,77	low_impact	-3,53	medium_impact	0,01	medium_impact	1,76	0,44	0,8	23,95	17,94	N	0,38	N	0,95	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15078	15078	A	C	MI.9032	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	332	111	E	A	gAa/gCa	4,31	1	0	probably_damaging	1	neutral	0,5	neutral	3,12	neutral	-0,42	deleterious	-4,81	medium_impact	2,96	neutral	0,94	neutral	0,54	deleterious	3,22	22,7	0,12	0,4	neutral	0,41	disease	0,78	disease	0,58	disease	0,51	0	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,79	low_impact	-3,53	medium_impact	0,22	medium_impact	1,49	0,32	0,8	23,95	17,94	N	0,48	N	0,82	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15078	15078	A	G	MI.9033	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	332	111	E	G	gAa/gGa	4,31	1	0	probably_damaging	1	neutral	0,36	neutral	3,11	neutral	-1,89	deleterious	-5,72	medium_impact	2,47	neutral	0,94	neutral	0,54	deleterious	3,85	23,4	0,13	0,4	disease	0,57	disease	0,79	disease	0,67	disease	0,53	1	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,8	low_impact	-3,53	medium_impact	0,09	medium_impact	1,05	0,3	0,8	23,95	17,94	N	0,52	P	0,77	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15078	15078	A	T	MI.9034	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	332	111	E	V	gAa/gTa	4,31	1	0	probably_damaging	1	neutral	0,54	neutral	3,08	neutral	-1,63	deleterious	-5,61	high_impact	3,6	neutral	0,94	neutral	0,53	deleterious	3,65	23,2	0,08	0,35	disease	0,6	disease	0,9	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,26	high_impact	2,08	0,33	0,8	23,95	17,94	N	0,48	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15079	15079	A	T	MI.9035	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	333	111	E	D	gaA/gaT	6,84	1	0	probably_damaging	0,98	neutral	0,2	neutral	3,1	neutral	-1	neutral	-2,48	high_impact	4,2	neutral	0,92	neutral	0,62	deleterious	1,97	16,01	0,35	0,5	neutral	0,45	disease	0,79	disease	0,51	disease	0,56	1	deleterious	0,98	neutral	0,11	deleterious	2	deleterious	0,77	low_impact	-2,31	medium_impact	-0,1	high_impact	2,62	0,5	0,8	23,95	17,94	P	0,67	P	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15079	15079	A	C	MI.9036	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	333	111	E	D	gaA/gaC	6,84	1	0	probably_damaging	0,98	neutral	0,2	neutral	3,1	neutral	-1	neutral	-2,48	high_impact	4,2	neutral	0,92	neutral	0,62	deleterious	1,86	15,37	0,35	0,5	neutral	0,45	disease	0,79	disease	0,51	disease	0,56	1	deleterious	0,98	neutral	0,11	deleterious	2	deleterious	0,77	low_impact	-2,31	medium_impact	-0,1	high_impact	2,62	0,5	0,8	23,95	17,94	P	0,66	P	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15080	15080	A	T	MI.9037	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	334	112	T	S	Acc/Tcc	-0,04	0,92	0	probably_damaging	0,99	neutral	0,46	neutral	3,15	neutral	-1,58	deleterious	-3,51	high_impact	3,92	neutral	0,84	neutral	0,49	deleterious	2,83	21,5	0,28	0,45	neutral	0,35	disease	0,75	disease	0,7	disease	0,68	4	deleterious	0,99	neutral	0,24	deleterious	2	deleterious	0,78	low_impact	-2,59	medium_impact	0,18	high_impact	2,37	0,42	0,8	56,84	8,7	N	0,39	N	0,81	polymorphism	1	0,03	rs386829235	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15080	15080	A	C	MI.9038	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	334	112	T	P	Acc/Ccc	-0,04	0,92	0	probably_damaging	1	neutral	0,22	neutral	3,09	deleterious	-3,25	deleterious	-5,29	high_impact	3,71	neutral	0,84	neutral	0,32	deleterious	3,33	22,9	0,04	0,35	disease	0,68	disease	0,85	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,08	high_impact	2,18	0,35	0,8	56,84	8,7	N	0,38	N	0,95	polymorphism	1	0,07	rs386829235	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15080	15080	A	G	MI.9039	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	334	112	T	A	Acc/Gcc	-0,04	0,92	0	probably_damaging	0,99	neutral	0,54	neutral	3,14	neutral	-1,58	deleterious	-4,36	medium_impact	3,05	neutral	0,78	neutral	0,54	deleterious	2,9	21,8	0,2	0,45	neutral	0,35	disease	0,7	disease	0,62	disease	0,53	1	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,75	low_impact	-2,59	medium_impact	0,26	medium_impact	1,58	0,32	0,8	56,84	8,7	N	0,3	N	0,59	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8951	8951	T	G	MI.904	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	425	142	V	G	gTt/gGt	1,29	0,65	0,01	benign	0,28	deleterious	0	neutral	4,01	deleterious	-4,8	deleterious	-6,21	medium_impact	3,27	neutral	0,78	neutral	0,49	deleterious	2,09	16,82	0,13	0,65	disease	0,87	disease	0,66	disease	0,64	disease	0,72	4	deleterious	1	neutral	0,36	deleterious	1	neutral	0,38	medium_impact	-0,37	low_impact	-1,4	medium_impact	1,71	0,52	0,9	11,95	13,75	N	0,32	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15081	15081	C	A	MI.9040	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	335	112	T	N	aCc/aAc	6,84	1	0	probably_damaging	1	neutral	0,36	neutral	3,12	neutral	-1,83	deleterious	-4,42	high_impact	4,51	neutral	0,83	neutral	0,44	deleterious	3,7	23,3	0,21	0,45	disease	0,53	disease	0,87	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,09	high_impact	2,9	0,49	0,8	56,84	8,7	P	0,65	P	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15081	15081	C	G	MI.9041	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	335	112	T	S	aCc/aGc	6,84	1	0	probably_damaging	0,99	neutral	0,46	neutral	3,15	neutral	-1,58	deleterious	-3,51	high_impact	3,92	neutral	0,84	neutral	0,49	deleterious	3,15	22,6	0,28	0,45	neutral	0,35	disease	0,75	disease	0,7	disease	0,68	4	deleterious	0,99	neutral	0,24	deleterious	2	deleterious	0,78	low_impact	-2,59	medium_impact	0,18	high_impact	2,37	0,42	0,8	56,84	8,7	P	0,57	P	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15081	15081	C	T	MI.9042	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	335	112	T	I	aCc/aTc	6,84	1	0	probably_damaging	1	neutral	0,44	neutral	3,08	deleterious	-3,02	deleterious	-5,29	high_impact	4,24	neutral	0,84	neutral	0,48	deleterious	3,82	23,4	0,08	0,35	neutral	0,37	disease	0,89	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,17	high_impact	2,66	0,42	0,8	56,84	8,7	N	0,5	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15083	15083	T	C	MI.9043	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	337	113	W	R	Tga/Cga	-6,7	0	0	probably_damaging	1	neutral	0,35	neutral	1,38	deleterious	-9,48	deleterious	-12,48	high_impact	4,8	neutral	0,71	neutral	0,29	deleterious	3,43	23	0,02	0,35	disease	0,69	disease	0,94	disease	0,87	disease	0,79	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,08	high_impact	3,17	0,07	0,8	57,89	8,78	P	0,52	P	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15083	15083	T	G	MI.9044	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	337	113	W	G	Tga/Gga	-6,7	0	0	probably_damaging	1	neutral	0,33	neutral	1,38	deleterious	-9,89	deleterious	-11,59	high_impact	4,94	neutral	0,74	neutral	0,43	deleterious	3,76	23,3	0,03	0,35	disease	0,9	disease	0,89	disease	0,84	disease	0,63	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,06	high_impact	3,29	0,06	0,8	57,89	8,78	P	0,58	P	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15084	15084	G	C	MI.9045	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	338	113	W	S	tGa/tCa	7,3	1	0	probably_damaging	1	neutral	0,4	neutral	1,38	deleterious	-9,33	deleterious	-12,48	high_impact	4,68	neutral	0,75	neutral	0,41	deleterious	3,89	23,5	0,02	0,35	disease	0,86	disease	0,93	disease	0,83	disease	0,64	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,13	high_impact	3,06	0,05	0,8	57,89	8,78	P	0,56	P	0,99	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15084	15084	G	T	MI.9046	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	338	113	W	L	tGa/tTa	7,3	1	0	probably_damaging	1	neutral	0,67	neutral	1,41	deleterious	-7,74	deleterious	-11,59	high_impact	5,14	neutral	0,74	neutral	0,35	deleterious	4,04	23,7	0,03	0,35	disease	0,69	disease	0,92	disease	0,82	disease	0,72	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,39	high_impact	3,47	0,03	0,8	57,89	8,78	P	0,62	P	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15085	15085	A	C	MI.9047	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	339	113	W	C	tgA/tgC	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	1,38	deleterious	-10,09	deleterious	-11,58	high_impact	4,8	neutral	0,88	neutral	0,29	deleterious	3,91	23,5	0,02	0,35	disease	0,95	disease	0,92	disease	0,86	disease	0,67	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,14	high_impact	3,17	0,05	0,8	57,89	8,78	P	0,57	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15085	15085	A	T	MI.9048	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	339	113	W	C	tgA/tgT	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	1,38	deleterious	-10,09	deleterious	-11,58	high_impact	4,8	neutral	0,88	neutral	0,29	deleterious	4,08	23,7	0,02	0,35	disease	0,95	disease	0,92	disease	0,86	disease	0,67	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,14	high_impact	3,17	0,05	0,8	57,89	8,78	P	0,57	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15086	15086	A	T	MI.9049	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	340	114	N	Y	Aac/Tac	2,02	1	0	probably_damaging	1	neutral	1	neutral	3,19	deleterious	-4,27	deleterious	-6,03	medium_impact	2,84	neutral	0,86	damaging	0,08	deleterious	3,64	23,2	0,1	0,4	disease	0,61	disease	0,9	neutral	0,43	neutral	0,45	1	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,83	low_impact	-3,53	high_impact	1,85	medium_impact	1,39	0,2	0,8	53,95	8,23	N	0,27	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8953	8953	A	T	MI.905	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	427	143	I	F	Att/Ttt	-5,42	0	0	probably_damaging	0,99	deleterious	0,03	neutral	4,24	neutral	-1,21	deleterious	-3,3	medium_impact	2,12	neutral	0,86	neutral	0,4	deleterious	3,79	23,4	0,3	0,65	neutral	0,45	disease	0,57	disease	0,65	disease	0,69	4	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,71	low_impact	-2,65	medium_impact	-0,56	medium_impact	0,72	0,75	0,9	19,47	13,18	N	0,35	N	0,76	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15086	15086	A	C	MI.9050	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	340	114	N	H	Aac/Cac	2,02	1	0	probably_damaging	1	neutral	0,53	neutral	3,16	deleterious	-3,83	deleterious	-3,86	high_impact	4,61	neutral	0,85	damaging	0,08	deleterious	3,04	22,3	0,31	0,45	disease	0,69	disease	0,86	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,25	high_impact	2,99	0,22	0,8	53,95	8,23	N	0,44	N	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15086	15086	A	G	MI.9051	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	340	114	N	D	Aac/Gac	2,02	1	0	probably_damaging	0,99	neutral	0,2	neutral	3,15	neutral	-2,64	deleterious	-4,04	high_impact	4,61	neutral	0,84	damaging	0,1	deleterious	3,42	23	0,46	0,55	disease	0,68	disease	0,83	disease	0,7	disease	0,68	4	deleterious	0,99	neutral	0,11	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	-0,1	high_impact	2,99	0,37	0,8	53,95	8,23	N	0,52	P	0,96	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15087	15087	A	C	MI.9052	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	341	114	N	T	aAc/aCc	8,44	1	0	probably_damaging	1	neutral	0,42	neutral	3,21	neutral	-0,06	deleterious	-4,62	medium_impact	2,23	neutral	0,85	damaging	0,27	deleterious	2,97	22,1	0,28	0,45	neutral	0,45	disease	0,8	neutral	0,35	neutral	0,18	6	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-3,53	medium_impact	0,15	medium_impact	0,83	0,28	0,8	53,95	8,23	N	0,47	N	0,94	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15087	15087	A	G	MI.9053	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	341	114	N	S	aAc/aGc	8,44	1	0	probably_damaging	0,98	neutral	0,41	neutral	3,19	neutral	-1,47	deleterious	-3,84	medium_impact	3,25	neutral	0,92	damaging	0,1	neutral	1,19	11,7	0,41	0,5	neutral	0,37	disease	0,8	neutral	0,4	neutral	0,19	6	neutral	0,98	neutral	0,22	deleterious	1	deleterious	0,77	low_impact	-2,31	medium_impact	0,14	medium_impact	1,76	0,2	0,8	53,95	8,23	N	0,51	P	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15087	15087	A	T	MI.9054	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	341	114	N	I	aAc/aTc	8,44	1	0	probably_damaging	1	neutral	0,42	neutral	3,44	deleterious	-3,33	deleterious	-7,09	medium_impact	3,04	neutral	0,86	damaging	0,11	deleterious	3,68	23,3	0,11	0,4	neutral	0,25	disease	0,93	neutral	0,36	disease	0,63	3	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-3,53	medium_impact	0,15	medium_impact	1,57	0,15	0,8	53,95	8,23	N	0,43	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15088	15088	C	G	MI.9055	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	342	114	N	K	aaC/aaG	6,84	1	0	probably_damaging	1	neutral	0,3	neutral	3,21	neutral	-2,23	deleterious	-4,77	high_impact	4,61	neutral	0,86	damaging	0,07	deleterious	3,77	23,4	0,32	0,5	disease	0,54	disease	0,88	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,02	high_impact	2,99	0,38	0,8	53,95	8,23	P	0,6	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15088	15088	C	A	MI.9056	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	342	114	N	K	aaC/aaA	6,84	1	0	probably_damaging	1	neutral	0,3	neutral	3,21	neutral	-2,23	deleterious	-4,77	high_impact	4,61	neutral	0,86	damaging	0,07	deleterious	4,27	23,9	0,32	0,5	disease	0,54	disease	0,88	disease	0,72	disease	0,68	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,02	high_impact	2,99	0,38	0,8	53,95	8,23	P	0,6	P	1	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15089	15089	A	C	MI.9057	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	343	115	I	L	Atc/Ctc	-2,34	0	0	benign	0,16	neutral	1	neutral	3,15	neutral	-0,06	neutral	-1,36	medium_impact	2,62	neutral	0,9	neutral	0,5	neutral	1,7	14,42	0,28	0,45	neutral	0,33	disease	0,74	neutral	0,48	neutral	0,17	7	neutral	0,16	deleterious	0,92	neutral	-3	neutral	0,22	medium_impact	-0,06	high_impact	1,85	medium_impact	1,19	0,5	0,8	18,16	13,07	N	0,23	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15089	15089	A	G	MI.9058	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	343	115	I	V	Atc/Gtc	-2,34	0	0	benign	0,01	neutral	0,62	neutral	3,01	neutral	-1,13	neutral	-0,38	low_impact	0,88	neutral	0,94	neutral	0,92	neutral	-0,28	0,75	0,37	0,5	neutral	0,21	neutral	0,25	neutral	0,45	neutral	0,41	2	neutral	0,37	deleterious	0,81	neutral	-6	neutral	0,12	medium_impact	1,13	medium_impact	0,34	medium_impact	-0,39	0,36	0,8	18,16	13,07	N	0,31	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15089	15089	A	T	MI.9059	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	343	115	I	F	Atc/Ttc	-2,34	0	0	possibly_damaging	0,81	neutral	0,67	neutral	2,9	neutral	-2,84	deleterious	-3,04	high_impact	3,88	neutral	0,85	neutral	0,4	deleterious	3,25	22,8	0,17	0,45	disease	0,64	disease	0,85	disease	0,71	disease	0,71	4	neutral	0,77	neutral	0,43	deleterious	1	deleterious	0,75	low_impact	-1,32	medium_impact	0,39	high_impact	2,33	0,4	0,8	18,16	13,07	N	0,26	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8953	8953	A	G	MI.906	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	427	143	I	V	Att/Gtt	-5,42	0	0	probably_damaging	0,93	neutral	0,13	neutral	4,3	neutral	0,03	neutral	-0,56	low_impact	1,05	neutral	0,9	neutral	0,94	neutral	1,62	13,97	0,57	0,65	neutral	0,36	neutral	0,18	neutral	0,4	neutral	0,29	4	neutral	0,97	neutral	0,1	neutral	-2	deleterious	0,58	low_impact	-1,82	medium_impact	-0,18	medium_impact	-0,2	0,56	0,9	19,47	13,18	N	0,53	P	0,13	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15090	15090	T	C	MI.9060	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	344	115	I	T	aTc/aCc	0,64	0	0	possibly_damaging	0,74	neutral	0,49	neutral	3,03	neutral	-0,96	deleterious	-2,66	low_impact	1,23	neutral	0,87	neutral	0,64	deleterious	1,91	15,68	0,09	0,4	neutral	0,43	disease	0,54	disease	0,52	neutral	0,21	6	neutral	0,72	neutral	0,38	neutral	-3	deleterious	0,59	low_impact	-1,16	medium_impact	0,21	medium_impact	-0,08	0,22	0,8	18,16	13,07	N	0,27	N	0,99	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15090	15090	T	G	MI.9061	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	344	115	I	S	aTc/aGc	0,64	0	0	probably_damaging	0,9	neutral	0,41	neutral	3,01	neutral	-1,05	deleterious	-3,98	low_impact	1,84	neutral	0,84	neutral	0,39	deleterious	4,09	23,7	0,03	0,35	neutral	0,31	disease	0,87	disease	0,52	disease	0,64	3	neutral	0,9	neutral	0,26	neutral	-2	deleterious	0,69	low_impact	-1,62	medium_impact	0,14	medium_impact	0,48	0,21	0,8	18,16	13,07	N	0,25	N	0,98	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15090	15090	T	A	MI.9062	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	344	115	I	N	aTc/aAc	0,64	0	0	probably_damaging	0,98	neutral	0,51	neutral	2,87	deleterious	-4,2	deleterious	-4,89	high_impact	4,22	neutral	0,83	neutral	0,41	deleterious	4,31	24	0,09	0,35	disease	0,78	disease	0,88	disease	0,7	disease	0,71	4	neutral	0,97	neutral	0,27	deleterious	2	deleterious	0,81	low_impact	-2,31	medium_impact	0,23	high_impact	2,64	0,26	0,8	18,16	13,07	N	0,38	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15091	15091	C	G	MI.9063	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	345	115	I	M	atC/atG	1,33	0	0	probably_damaging	0,9	neutral	0,36	neutral	2,89	deleterious	-3,1	neutral	-1,89	medium_impact	2,27	neutral	0,9	neutral	0,64	deleterious	2,99	22,2	0,24	0,45	disease	0,63	disease	0,66	disease	0,62	neutral	0,47	1	neutral	0,91	neutral	0,23	deleterious	1	deleterious	0,67	low_impact	-1,62	medium_impact	0,09	medium_impact	0,87	0,49	0,8	18,16	13,07	N	0,34	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15091	15091	C	A	MI.9064	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	345	115	I	M	atC/atA	1,33	0	0	probably_damaging	0,9	neutral	0,36	neutral	2,89	deleterious	-3,1	neutral	-1,89	medium_impact	2,27	neutral	0,9	neutral	0,64	deleterious	3,5	23,1	0,24	0,45	disease	0,63	disease	0,66	disease	0,62	neutral	0,47	1	neutral	0,91	neutral	0,23	deleterious	1	deleterious	0,67	low_impact	-1,62	medium_impact	0,09	medium_impact	0,87	0,49	0,8	18,16	13,07	N	0,34	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15092	15092	G	A	MI.9065	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	346	116	G	S	Ggc/Agc	-8,53	0	0	possibly_damaging	0,86	neutral	0,49	neutral	1,43	deleterious	-8,91	deleterious	-5,36	high_impact	5,16	neutral	0,78	neutral	0,34	deleterious	4,07	23,7	0,03	0,35	disease	0,92	disease	0,85	disease	0,78	disease	0,64	3	neutral	0,85	neutral	0,32	deleterious	1	deleterious	0,81	low_impact	-1,47	medium_impact	0,21	high_impact	3,49	0,55	0,8	58,16	8,71	P	0,74	P	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	G15092A	MELAS	-	+	Reported	1
chrM	15092	15092	G	C	MI.9066	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	346	116	G	R	Ggc/Cgc	-8,53	0	0	probably_damaging	0,99	neutral	0,33	neutral	1,39	deleterious	-9,83	deleterious	-7,14	high_impact	5,16	neutral	0,79	damaging	0,24	deleterious	3,8	23,4	0,01	0,35	disease	0,96	disease	0,92	disease	0,86	disease	0,66	3	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,91	low_impact	-2,59	medium_impact	0,06	high_impact	3,49	0,47	0,8	58,16	8,71	P	0,6	P	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15092	15092	G	T	MI.9067	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	346	116	G	C	Ggc/Tgc	-8,53	0	0	probably_damaging	0,99	neutral	0,17	neutral	1,38	deleterious	-12,02	deleterious	-8,04	high_impact	5,5	neutral	0,79	damaging	0,23	deleterious	4,02	23,6	0,02	0,35	disease	0,97	disease	0,91	disease	0,79	disease	0,67	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-2,59	medium_impact	-0,15	high_impact	3,8	0,24	0,8	58,16	8,71	P	0,55	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15093	15093	G	A	MI.9068	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	347	116	G	D	gGc/gAc	5	1	0	benign	0,16	neutral	0,19	neutral	1,39	deleterious	-9,44	deleterious	-6,25	high_impact	5,5	damaging	0,58	neutral	0,3	deleterious	3,73	23,3	0,01	0,35	disease	0,95	disease	0,91	disease	0,86	disease	0,67	3	neutral	0,78	deleterious	0,52	neutral	-2	deleterious	0,5	medium_impact	-0,06	medium_impact	-0,12	high_impact	3,8	0,15	0,8	58,16	8,71	P	0,56	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15093	15093	G	T	MI.9069	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	347	116	G	V	gGc/gTc	5	1	0	probably_damaging	0,99	neutral	1	neutral	1,42	deleterious	-11,25	deleterious	-8,04	high_impact	5,5	neutral	0,79	neutral	0,37	deleterious	3,71	23,3	0,01	0,35	disease	0,96	disease	0,9	disease	0,77	disease	0,62	2	deleterious	0,99	deleterious	0,51	deleterious	2	deleterious	0,88	low_impact	-2,59	high_impact	1,85	high_impact	3,8	0,16	0,8	58,16	8,71	P	0,63	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8953	8953	A	C	MI.907	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	427	143	I	L	Att/Ctt	-5,42	0	0	probably_damaging	0,93	neutral	0,94	neutral	4,44	neutral	0,51	neutral	-1,35	neutral_impact	0,41	neutral	0,9	neutral	0,8	deleterious	2,55	19,77	0,38	0,65	neutral	0,33	neutral	0,21	neutral	0,32	neutral	0,36	3	neutral	0,92	deleterious	0,51	neutral	-2	deleterious	0,58	low_impact	-1,82	medium_impact	0,97	medium_impact	-0,75	0,67	0,9	19,47	13,18	N	0,26	N	0,31	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15093	15093	G	C	MI.9070	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	347	116	G	A	gGc/gCc	5	1	0	possibly_damaging	0,81	neutral	0,61	neutral	1,45	deleterious	-8,53	deleterious	-5,36	high_impact	5,5	neutral	0,8	neutral	0,43	deleterious	3,04	22,4	0,03	0,35	disease	0,9	disease	0,76	disease	0,77	disease	0,67	3	neutral	0,78	neutral	0,4	deleterious	1	deleterious	0,79	low_impact	-1,32	medium_impact	0,33	high_impact	3,8	0,32	0,8	58,16	8,71	P	0,69	P	0,83	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15095	15095	A	G	MI.9071	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	349	117	I	V	Att/Gtt	-1,65	0	0	benign	0,02	neutral	0,5	neutral	3,61	neutral	2,02	neutral	0,43	neutral_impact	-1,34	neutral	0,93	neutral	0,95	neutral	-1,53	0	0,33	0,5	neutral	0,21	neutral	0,05	neutral	0,32	neutral	0,17	7	neutral	0,48	deleterious	0,74	neutral	-6	neutral	0,09	medium_impact	0,85	medium_impact	0,22	low_impact	-2,41	0,54	0,8	13,95	23,32	N	0,36	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15095	15095	A	T	MI.9072	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	349	117	I	F	Att/Ttt	-1,65	0	0	possibly_damaging	0,79	neutral	0,7	neutral	3,08	neutral	-1,07	deleterious	-3,5	medium_impact	2,48	neutral	0,92	neutral	0,52	deleterious	3,45	23	0,08	0,35	disease	0,54	disease	0,85	disease	0,63	disease	0,73	5	neutral	0,74	neutral	0,46	NA	0	deleterious	0,67	low_impact	-1,27	medium_impact	0,42	medium_impact	1,06	0,45	0,8	13,95	23,32	N	0,23	N	0,95	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15095	15095	A	C	MI.9073	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	349	117	I	L	Att/Ctt	-1,65	0	0	benign	0,14	neutral	0,65	neutral	3,2	neutral	0,2	neutral	-1,74	medium_impact	2,25	neutral	0,84	neutral	0,46	deleterious	1,94	15,83	0,17	0,45	neutral	0,21	disease	0,75	disease	0,58	disease	0,68	4	neutral	0,23	deleterious	0,76	neutral	-3	neutral	0,19	medium_impact	0	medium_impact	0,37	medium_impact	0,85	0,52	0,8	13,95	23,32	N	0,24	N	0,59	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15096	15096	T	G	MI.9074	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	350	117	I	S	aTt/aGt	0,18	0,02	0	possibly_damaging	0,79	neutral	0,4	neutral	3,06	neutral	-1,6	deleterious	-4,54	medium_impact	2,21	neutral	0,84	neutral	0,46	deleterious	3,86	23,5	0,02	0,35	disease	0,57	disease	0,85	disease	0,6	disease	0,73	5	neutral	0,79	neutral	0,31	NA	0	deleterious	0,56	low_impact	-1,27	medium_impact	0,13	medium_impact	0,81	0,35	0,8	13,95	23,32	N	0,26	N	0,95	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15096	15096	T	A	MI.9075	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	350	117	I	N	aTt/aAt	0,18	0,02	0	probably_damaging	0,94	neutral	0,31	neutral	3,02	deleterious	-3,22	deleterious	-5,43	medium_impact	2,99	neutral	0,83	neutral	0,48	deleterious	4,08	23,7	0,03	0,35	disease	0,74	disease	0,9	disease	0,62	disease	0,73	5	neutral	0,95	neutral	0,19	deleterious	1	deleterious	0,79	low_impact	-1,85	medium_impact	0,03	medium_impact	1,52	0,43	0,8	13,95	23,32	N	0,3	N	0,98	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15096	15096	T	C	MI.9076	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	350	117	I	T	aTt/aCt	0,18	0,02	0	possibly_damaging	0,52	neutral	0,39	neutral	3,08	neutral	-1,14	deleterious	-2,94	low_impact	1,28	neutral	0,94	neutral	0,69	neutral	1,65	14,15	0,03	0,35	neutral	0,42	disease	0,67	neutral	0,44	neutral	0,35	3	neutral	0,6	neutral	0,44	neutral	-3	neutral	0,43	medium_impact	-0,76	medium_impact	0,12	medium_impact	-0,03	0,28	0,8	13,95	23,32	N	0,34	N	0,97	polymorphism	1	0,04	rs1057516073	Uncertain significance	Mitochondrial_myopathy	RCV000408930.1	MedGen:OMIM:Orphanet	.	.	.	.	.	.	.	.	.	.
chrM	15097	15097	T	A	MI.9077	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	351	117	I	M	atT/atA	5,69	0,87	0	possibly_damaging	0,89	neutral	0,22	neutral	3,05	neutral	-2,01	neutral	-1,97	medium_impact	2,48	neutral	0,89	neutral	0,48	deleterious	3,37	22,9	0,12	0,4	disease	0,52	disease	0,69	disease	0,53	neutral	0,49	0	neutral	0,93	neutral	0,17	NA	0	deleterious	0,63	low_impact	-1,58	medium_impact	-0,08	medium_impact	1,06	0,51	0,8	13,95	23,32	N	0,53	P	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15097	15097	T	G	MI.9078	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	351	117	I	M	atT/atG	5,69	0,87	0	possibly_damaging	0,89	neutral	0,22	neutral	3,05	neutral	-2,01	neutral	-1,97	medium_impact	2,48	neutral	0,89	neutral	0,48	deleterious	3,05	22,4	0,12	0,4	disease	0,52	disease	0,69	disease	0,53	neutral	0,49	0	neutral	0,93	neutral	0,17	NA	0	deleterious	0,63	low_impact	-1,58	medium_impact	-0,08	medium_impact	1,06	0,51	0,8	13,95	23,32	N	0,52	P	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15098	15098	A	G	MI.9079	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	352	118	I	V	Atc/Gtc	-11,97	0	0	benign	0	neutral	1	neutral	3,17	neutral	-1,62	neutral	-0,34	neutral_impact	0,44	neutral	0,98	neutral	0,94	neutral	-0,36	0,49	0,35	0,5	neutral	0,17	neutral	0,13	neutral	0,35	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,1	high_impact	2,07	high_impact	1,85	medium_impact	-0,79	0,51	0,8	22,63	27,86	N	0,37	N	0,04	polymorphism	1	0,01	rs527236172	Likely pathogenic	Neoplasm_of_ovary	RCV000133414.1	Gene:MedGen:OMIM:SNOMED_CT	.	.	.	5,5	.	.	.	.	.	.
chrM	8954	8954	T	C	MI.908	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	428	143	I	T	aTt/aCt	-0,33	0	0	probably_damaging	0,99	deleterious	0,04	neutral	4,22	neutral	-1,7	deleterious	-3,89	medium_impact	2,65	neutral	0,9	neutral	0,44	deleterious	3,34	22,9	0,32	0,65	disease	0,62	neutral	0,43	disease	0,6	disease	0,64	3	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,72	low_impact	-2,65	medium_impact	-0,49	medium_impact	1,17	0,66	0,9	19,47	13,18	N	0,47	N	0,66	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15098	15098	A	C	MI.9080	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	352	118	I	L	Atc/Ctc	-11,97	0	0	benign	0,02	neutral	0,63	neutral	3,27	neutral	-1,31	neutral	-1,21	low_impact	1,31	neutral	0,97	neutral	0,86	deleterious	0,36	6,22	0,2	0,45	neutral	0,37	disease	0,58	neutral	0,31	neutral	0,22	6	neutral	0,33	deleterious	0,81	neutral	-6	neutral	0,18	medium_impact	0,85	medium_impact	0,35	medium_impact	0	0,5	0,8	22,63	27,86	N	0,28	N	0,28	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15098	15098	A	T	MI.9081	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	352	118	I	F	Atc/Ttc	-11,97	0	0	benign	0,33	neutral	0,23	neutral	3,11	neutral	-1,04	deleterious	-3,13	medium_impact	3,27	neutral	0,95	neutral	0,5	deleterious	2,08	16,75	0,11	0,4	disease	0,76	disease	0,84	disease	0,6	disease	0,68	4	neutral	0,72	neutral	0,45	neutral	-3	deleterious	0,57	medium_impact	-0,44	medium_impact	-0,06	medium_impact	1,78	0,49	0,8	22,63	27,86	N	0,37	N	0,63	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15099	15099	T	C	MI.9082	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	353	118	I	T	aTc/aCc	-1,65	0	0	benign	0,39	neutral	0,27	neutral	3,1	neutral	-1,84	deleterious	-3,46	low_impact	1,8	neutral	0,93	neutral	0,57	deleterious	2,86	21,7	0,05	0,35	disease	0,53	disease	0,71	neutral	0,4	neutral	0,37	3	neutral	0,68	neutral	0,44	neutral	-6	deleterious	0,47	medium_impact	-0,55	medium_impact	-0,01	medium_impact	0,44	0,25	0,8	22,63	27,86	N	0,32	N	0,49	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15099	15099	T	G	MI.9083	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	353	118	I	S	aTc/aGc	-1,65	0	0	possibly_damaging	0,56	neutral	0,12	neutral	3,02	deleterious	-3,49	deleterious	-4,5	medium_impact	2,4	neutral	0,94	neutral	0,47	deleterious	3,85	23,4	0,02	0,35	disease	0,8	disease	0,86	disease	0,57	disease	0,66	3	neutral	0,87	neutral	0,28	NA	0	deleterious	0,67	medium_impact	-0,83	medium_impact	-0,25	medium_impact	0,99	0,28	0,8	22,63	27,86	N	0,41	N	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15099	15099	T	A	MI.9084	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	353	118	I	N	aTc/aAc	-1,65	0	0	possibly_damaging	0,87	neutral	0,08	neutral	2,99	deleterious	-4,65	deleterious	-5,43	high_impact	4,25	neutral	0,93	neutral	0,48	deleterious	4,07	23,7	0,06	0,35	disease	0,89	disease	0,87	disease	0,59	disease	0,64	3	neutral	0,96	neutral	0,11	deleterious	1	deleterious	0,78	low_impact	-1,5	medium_impact	-0,35	high_impact	2,67	0,36	0,8	22,63	27,86	N	0,48	N	0,63	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15100	15100	C	A	MI.9085	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	354	118	I	M	atC/atA	5,69	0,87	0,01	benign	0,04	neutral	0,33	neutral	3,02	neutral	-1,97	neutral	-1,71	low_impact	1,61	neutral	0,97	neutral	0,82	deleterious	2,26	17,89	0,19	0,45	disease	0,67	disease	0,6	neutral	0,35	neutral	0,25	5	neutral	0,64	deleterious	0,65	neutral	-6	neutral	0,23	medium_impact	0,56	medium_impact	0,06	medium_impact	0,27	0,53	0,8	22,63	27,86	N	0,44	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15100	15100	C	G	MI.9086	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	354	118	I	M	atC/atG	5,69	0,87	0,01	benign	0,04	neutral	0,33	neutral	3,02	neutral	-1,97	neutral	-1,71	low_impact	1,61	neutral	0,97	neutral	0,82	neutral	1,79	14,91	0,19	0,45	disease	0,67	disease	0,6	neutral	0,35	neutral	0,25	5	neutral	0,64	deleterious	0,65	neutral	-6	neutral	0,23	medium_impact	0,56	medium_impact	0,06	medium_impact	0,27	0,53	0,8	22,63	27,86	N	0,44	N	0,02	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15101	15101	C	T	MI.9087	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	355	119	L	F	Ctc/Ttc	-2,8	0	0	probably_damaging	1	neutral	0,41	neutral	2,54	deleterious	-4,82	deleterious	-3,53	high_impact	4,58	neutral	0,92	damaging	0,1	deleterious	3,86	23,5	0,08	0,35	disease	0,67	disease	0,78	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,14	high_impact	2,97	0,41	0,8	56,84	8,63	N	0,44	N	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15101	15101	C	A	MI.9088	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	355	119	L	I	Ctc/Atc	-2,8	0	0	probably_damaging	1	neutral	0,65	neutral	2,7	neutral	-1,98	neutral	-1,72	low_impact	1,44	neutral	0,87	damaging	0,11	deleterious	3,84	23,4	0,2	0,45	neutral	0,15	disease	0,66	neutral	0,32	neutral	0,18	6	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,71	low_impact	-3,53	medium_impact	0,37	medium_impact	0,11	0,57	0,8	56,84	8,63	N	0,19	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15101	15101	C	G	MI.9089	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	355	119	L	V	Ctc/Gtc	-2,8	0	0	probably_damaging	0,99	neutral	0,37	neutral	2,6	deleterious	-3,89	deleterious	-2,6	high_impact	4,58	neutral	0,91	damaging	0,12	deleterious	2,98	22,2	0,16	0,45	neutral	0,41	disease	0,65	disease	0,55	disease	0,62	2	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,75	low_impact	-2,59	medium_impact	0,1	high_impact	2,97	0,57	0,8	56,84	8,63	N	0,4	N	0,91	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8954	8954	T	A	MI.909	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	428	143	I	N	aTt/aAt	-0,33	0	0	probably_damaging	1	deleterious	0	neutral	4,17	deleterious	-3,45	deleterious	-5,83	high_impact	3,62	neutral	0,84	neutral	0,42	deleterious	4,33	24	0,21	0,65	disease	0,82	disease	0,62	disease	0,66	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,77	low_impact	-3,6	low_impact	-1,4	high_impact	2,01	0,61	0,9	19,47	13,18	N	0,35	N	0,86	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15102	15102	T	C	MI.9090	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	356	119	L	P	cTc/cCc	-0,04	0	0	probably_damaging	1	deleterious	0,02	neutral	2,51	deleterious	-7,28	deleterious	-6,22	high_impact	5,13	neutral	0,87	damaging	0,06	deleterious	3,83	23,4	0,02	0,35	disease	0,92	disease	0,85	disease	0,72	disease	0,63	3	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,89	low_impact	-3,53	medium_impact	-0,69	high_impact	3,46	0,31	0,8	56,84	8,63	P	0,58	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15102	15102	T	G	MI.9091	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	356	119	L	R	cTc/cGc	-0,04	0	0	probably_damaging	1	deleterious	0,04	neutral	2,52	deleterious	-6,44	deleterious	-5,34	high_impact	5,13	neutral	0,87	damaging	0,06	deleterious	4,09	23,7	0,02	0,35	disease	0,91	disease	0,91	disease	0,72	disease	0,63	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,91	low_impact	-3,53	medium_impact	-0,53	high_impact	3,46	0,22	0,8	56,84	8,63	P	0,61	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15102	15102	T	A	MI.9092	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	356	119	L	H	cTc/cAc	-0,04	0	0	probably_damaging	1	neutral	0,06	neutral	2,51	deleterious	-7,36	deleterious	-6,22	high_impact	5,13	neutral	0,85	damaging	0,08	deleterious	4,06	23,7	0,03	0,35	disease	0,95	disease	0,83	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,43	high_impact	3,46	0,37	0,8	56,84	8,63	P	0,57	P	0,95	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15104	15104	C	G	MI.9093	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	358	120	L	V	Ctg/Gtg	-11,74	0	0	probably_damaging	0,99	neutral	0,27	neutral	2,66	deleterious	-3,01	deleterious	-2,55	high_impact	4,59	neutral	0,87	damaging	0,1	deleterious	3,13	22,6	0,16	0,45	disease	0,67	disease	0,69	disease	0,59	disease	0,62	2	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,8	low_impact	-2,59	medium_impact	-0,01	high_impact	2,97	0,64	0,8	56,58	8,32	N	0,43	N	0,71	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15104	15104	C	A	MI.9094	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	358	120	L	M	Ctg/Atg	-11,74	0	0	probably_damaging	1	neutral	0,28	neutral	2,62	deleterious	-3,59	neutral	-1,64	high_impact	3,7	neutral	0,92	damaging	0,19	deleterious	3,67	23,2	0,13	0,4	disease	0,74	disease	0,66	neutral	0,38	neutral	0,33	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	0	high_impact	2,17	0,44	0,8	56,58	8,32	N	0,36	N	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15105	15105	T	C	MI.9095	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	359	120	L	P	cTg/cCg	-0,73	0	0	probably_damaging	1	deleterious	0,03	neutral	2,57	deleterious	-6,29	deleterious	-6,05	high_impact	5,14	neutral	0,87	damaging	0,06	deleterious	3,83	23,4	0,02	0,35	disease	0,91	disease	0,88	disease	0,7	disease	0,62	2	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,89	low_impact	-3,53	medium_impact	-0,6	high_impact	3,47	0,44	0,8	56,58	8,32	P	0,59	P	0,92	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15105	15105	T	A	MI.9096	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	359	120	L	Q	cTg/cAg	-0,73	0	0	probably_damaging	1	deleterious	0,04	neutral	2,58	deleterious	-5,67	deleterious	-5,15	high_impact	5,14	neutral	0,86	damaging	0,07	deleterious	4,1	23,7	0,02	0,35	disease	0,88	disease	0,84	disease	0,58	disease	0,63	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-3,53	medium_impact	-0,53	high_impact	3,47	0,32	0,8	56,58	8,32	P	0,58	P	0,92	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15105	15105	T	G	MI.9097	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	359	120	L	R	cTg/cGg	-0,73	0	0	probably_damaging	1	deleterious	0,04	neutral	2,58	deleterious	-5,73	deleterious	-5,16	high_impact	5,14	neutral	0,87	damaging	0,06	deleterious	4,1	23,7	0,01	0,35	disease	0,88	disease	0,93	disease	0,7	disease	0,65	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,92	low_impact	-3,53	medium_impact	-0,53	high_impact	3,47	0,17	0,8	56,58	8,32	P	0,61	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15107	15107	C	T	MI.9098	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	361	121	L	F	Ctt/Ttt	-3,49	0	0	benign	0,03	neutral	0,42	neutral	2,87	neutral	-2,57	neutral	-0,94	neutral_impact	0,52	neutral	0,97	neutral	0,89	neutral	1,09	11,16	0,24	0,45	neutral	0,28	neutral	0,26	neutral	0,29	neutral	0,42	2	neutral	0,56	deleterious	0,7	neutral	-6	neutral	0,17	medium_impact	0,68	medium_impact	0,15	medium_impact	-0,72	0,44	0,8	17,89	17,41	N	0,43	N	0,17	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15107	15107	C	A	MI.9099	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	361	121	L	I	Ctt/Att	-3,49	0	0	benign	0,36	neutral	0,32	neutral	2,94	neutral	-1,91	neutral	-1,2	low_impact	1,86	neutral	0,91	neutral	0,7	deleterious	2,68	20,7	0,29	0,45	neutral	0,31	disease	0,78	neutral	0,3	neutral	0,2	6	neutral	0,62	deleterious	0,48	neutral	-6	neutral	0,3	medium_impact	-0,5	medium_impact	0,05	medium_impact	0,5	0,5	0,8	17,89	17,41	N	0,38	N	0,29	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8567	8567	T	A	MI.91	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	41	14	I	N	aTc/aAc	-4,27	0	0	probably_damaging	0,91	neutral	0,23	neutral	4,56	neutral	-1,01	deleterious	-3,91	low_impact	0,98	neutral	0,86	neutral	0,46	deleterious	4,28	24	0,35	0,65	neutral	0,27	disease	0,66	disease	0,66	disease	0,69	4	neutral	0,93	neutral	0,16	neutral	-2	deleterious	0,63	low_impact	-1,71	medium_impact	-0,01	medium_impact	-0,26	0,65	0,9	13,72	12,42	N	0,34	N	0,68	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8954	8954	T	G	MI.910	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	428	143	I	S	aTt/aGt	-0,33	0	0	probably_damaging	0,99	deleterious	0	neutral	4,2	neutral	-1,97	deleterious	-4,87	medium_impact	2,93	neutral	0,82	neutral	0,45	deleterious	4,25	23,9	0,2	0,65	disease	0,68	disease	0,67	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,76	low_impact	-2,65	low_impact	-1,4	medium_impact	1,41	0,63	0,9	19,47	13,18	N	0,33	N	0,74	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15107	15107	C	G	MI.9100	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	361	121	L	V	Ctt/Gtt	-3,49	0	0	benign	0,17	neutral	0,27	neutral	2,95	neutral	-1,79	neutral	-2,08	medium_impact	3,29	neutral	0,95	neutral	0,69	neutral	1,65	14,13	0,28	0,45	neutral	0,43	disease	0,72	neutral	0,46	neutral	0,35	3	neutral	0,68	deleterious	0,55	neutral	-3	neutral	0,27	medium_impact	-0,09	medium_impact	-0,01	medium_impact	1,79	0,58	0,8	17,89	17,41	N	0,35	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15108	15108	T	C	MI.9101	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	362	121	L	P	cTt/cCt	-0,73	0	0	probably_damaging	0,97	deleterious	0,03	neutral	2,76	deleterious	-4,7	deleterious	-5,41	high_impact	4,89	neutral	0,93	neutral	0,42	deleterious	3,76	23,3	0,03	0,35	disease	0,84	disease	0,92	disease	0,67	disease	0,64	3	deleterious	1	neutral	0,03	deleterious	6	deleterious	0,88	low_impact	-2,14	medium_impact	-0,6	high_impact	3,25	0,33	0,8	17,89	17,41	P	0,63	P	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15108	15108	T	G	MI.9102	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	362	121	L	R	cTt/cGt	-0,73	0	0	probably_damaging	0,9	neutral	0,05	neutral	2,77	deleterious	-3,88	deleterious	-4,54	high_impact	4,89	neutral	0,94	neutral	0,53	deleterious	3,67	23,3	0,02	0,35	disease	0,79	disease	0,95	disease	0,67	disease	0,73	5	deleterious	0,98	neutral	0,08	deleterious	2	deleterious	0,86	low_impact	-1,62	medium_impact	-0,47	high_impact	3,25	0,17	0,8	17,89	17,41	P	0,68	P	0,9	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15108	15108	T	A	MI.9103	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	362	121	L	H	cTt/cAt	-0,73	0	0	probably_damaging	0,95	neutral	0,08	neutral	2,76	deleterious	-4,67	deleterious	-4,64	high_impact	4,89	neutral	0,93	neutral	0,55	deleterious	3,98	23,6	0,04	0,35	disease	0,84	disease	0,87	disease	0,63	disease	0,64	3	deleterious	0,99	neutral	0,07	deleterious	2	deleterious	0,82	low_impact	-1,92	medium_impact	-0,35	high_impact	3,25	0,24	0,8	17,89	17,41	P	0,68	P	0,8	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15110	15110	G	C	MI.9104	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	364	122	A	P	Gca/Cca	-11,28	0	0,01	possibly_damaging	0,72	neutral	0,08	neutral	3,12	neutral	-2,24	neutral	-1,95	medium_impact	2,67	neutral	0,84	neutral	0,29	deleterious	1,82	15,08	0,05	0,35	disease	0,64	disease	0,94	disease	0,63	disease	0,8	6	neutral	0,94	neutral	0,18	NA	0	deleterious	0,7	low_impact	-1,11	medium_impact	-0,35	medium_impact	1,23	0,59	0,8	21,32	28,06	N	0,29	N	0,73	polymorphism	1	0,05	rs28357685	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15110	15110	G	T	MI.9105	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	364	122	A	S	Gca/Tca	-11,28	0	0,01	benign	0,32	neutral	0,11	neutral	3,14	neutral	-0,74	neutral	-0,74	low_impact	1,86	neutral	0,9	neutral	0,72	deleterious	0,52	7,57	0,29	0,45	neutral	0,42	disease	0,66	neutral	0,48	neutral	0,3	4	neutral	0,87	neutral	0,4	neutral	-6	neutral	0,28	medium_impact	-0,43	medium_impact	-0,27	medium_impact	0,5	0,52	0,8	21,32	28,06	N	0,43	N	0,61	polymorphism	1	0,02	rs28357685	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15110	15110	G	A	MI.9106	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	364	122	A	T	Gca/Aca	-11,28	0	0,01	benign	0,01	neutral	0,27	neutral	3,16	neutral	-0,21	neutral	0,04	neutral_impact	-0,31	neutral	0,99	neutral	0,95	deleterious	-0,03	2,31	0,18	0,45	neutral	0,16	neutral	0,36	neutral	0,29	neutral	0,43	1	neutral	0,72	deleterious	0,63	neutral	-6	neutral	0,11	medium_impact	1,13	medium_impact	-0,01	low_impact	-1,48	0,81	0,85	21,32	28,06	N	0,45	N	0,02	polymorphism	1	0,01	rs28357685	.	.	.	.	.	COSM1138298	.	.	.	.	.	.	.	.
chrM	15111	15111	C	T	MI.9107	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	365	122	A	V	gCa/gTa	-3,49	0	0	benign	0,32	neutral	0,31	neutral	3,33	neutral	1,9	neutral	0,82	neutral_impact	0,66	neutral	0,92	neutral	0,68	neutral	1,11	11,25	0,17	0,45	neutral	0,14	disease	0,79	neutral	0,32	neutral	0,42	2	neutral	0,63	deleterious	0,5	neutral	-6	neutral	0,23	medium_impact	-0,43	medium_impact	0,03	medium_impact	-0,59	0,73	0,85	21,32	28,06	N	0,3	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	COSM1138300	.	.	.	.	.	.	.	.
chrM	15111	15111	C	A	MI.9108	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	365	122	A	E	gCa/gAa	-3,49	0	0	possibly_damaging	0,52	neutral	0,11	neutral	3,12	neutral	-1,97	neutral	-1,92	medium_impact	2,67	neutral	0,82	neutral	0,43	deleterious	2,4	18,84	0,04	0,35	disease	0,57	disease	0,91	disease	0,62	disease	0,76	5	neutral	0,88	neutral	0,3	NA	0	deleterious	0,46	medium_impact	-0,76	medium_impact	-0,27	medium_impact	1,23	0,31	0,8	21,32	28,06	N	0,3	N	0,65	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15111	15111	C	G	MI.9109	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	365	122	A	G	gCa/gGa	-3,49	0	0	benign	0,32	neutral	0,29	neutral	3,12	neutral	-1,74	deleterious	-2,56	medium_impact	2,67	neutral	0,82	neutral	0,5	deleterious	1,97	16,04	0,26	0,45	disease	0,57	disease	0,73	neutral	0,48	neutral	0,44	1	neutral	0,65	deleterious	0,49	neutral	-3	neutral	0,36	medium_impact	-0,43	medium_impact	0,01	medium_impact	1,23	0,66	0,8	21,32	28,06	N	0,29	N	0,54	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8955	8955	T	A	MI.911	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	429	143	I	M	atT/atA	3,83	0,45	0	probably_damaging	1	neutral	0,18	neutral	4,22	neutral	-2,18	neutral	-1,87	low_impact	1,28	neutral	0,9	neutral	0,95	deleterious	2,56	19,85	0,4	0,65	disease	0,62	neutral	0,23	neutral	0,38	disease	0,55	1	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	-0,08	medium_impact	0	0,74	0,9	19,47	13,18	N	0,5	N	0,73	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15113	15113	A	G	MI.9110	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	367	123	T	A	Act/Gct	-4,4	0	0	probably_damaging	1	neutral	0,49	neutral	2,99	neutral	-1,06	neutral	-1,06	medium_impact	2,34	neutral	0,98	neutral	0,74	deleterious	3,06	22,4	0,25	0,45	neutral	0,41	disease	0,76	neutral	0,46	neutral	0,49	0	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,71	low_impact	-3,53	medium_impact	0,21	medium_impact	0,93	0,37	0,8	15	16,14	N	0,33	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15113	15113	A	T	MI.9111	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	367	123	T	S	Act/Tct	-4,4	0	0	probably_damaging	1	neutral	0,2	neutral	2,97	neutral	-2,2	neutral	-2,01	low_impact	1,4	neutral	0,94	neutral	0,61	deleterious	3	22,2	0,38	0,5	disease	0,52	disease	0,78	neutral	0,37	neutral	0,43	1	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,76	low_impact	-3,53	medium_impact	-0,1	medium_impact	0,08	0,55	0,8	15	16,14	N	0,35	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15113	15113	A	C	MI.9112	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	367	123	T	P	Act/Cct	-4,4	0	0	probably_damaging	1	neutral	0,13	neutral	2,88	deleterious	-4,64	deleterious	-2,63	high_impact	4,08	neutral	0,94	neutral	0,43	deleterious	3,29	22,8	0,05	0,35	disease	0,73	disease	0,96	disease	0,64	disease	0,77	5	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,23	high_impact	2,51	0,3	0,8	15	16,14	N	0,44	N	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15114	15114	C	A	MI.9113	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	368	123	T	N	aCt/aAt	-0,5	0	0	probably_damaging	1	neutral	0,1	neutral	2,88	deleterious	-4,25	deleterious	-2,92	high_impact	3,73	neutral	0,93	neutral	0,62	deleterious	3,49	23,1	0,25	0,45	disease	0,69	disease	0,91	disease	0,59	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,3	high_impact	2,19	0,53	0,8	15	16,14	N	0,44	N	0,87	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15114	15114	C	T	MI.9114	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	368	123	T	I	aCt/aTt	-0,5	0	0	probably_damaging	1	neutral	0,59	neutral	2,99	neutral	-2,01	neutral	0,68	low_impact	1,73	neutral	0,94	neutral	0,84	deleterious	3,59	23,2	0,15	0,4	neutral	0,31	disease	0,91	neutral	0,4	neutral	0,2	6	deleterious	1	neutral	0,3	neutral	-2	deleterious	0,75	low_impact	-3,53	medium_impact	0,31	medium_impact	0,38	0,68	0,85	15	16,14	N	0,25	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15114	15114	C	G	MI.9115	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	368	123	T	S	aCt/aGt	-0,5	0	0	probably_damaging	1	neutral	0,2	neutral	2,97	neutral	-2,2	neutral	-2,01	low_impact	1,4	neutral	0,94	neutral	0,61	deleterious	3,12	22,6	0,38	0,5	disease	0,52	disease	0,78	neutral	0,37	neutral	0,43	1	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,76	low_impact	-3,53	medium_impact	-0,1	medium_impact	0,08	0,55	0,8	15	16,14	N	0,36	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15116	15116	A	C	MI.9116	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	370	124	M	L	Ata/Cta	-20	0	0	probably_damaging	0,93	neutral	0,98	neutral	3,24	neutral	0,33	deleterious	-2,67	high_impact	4,46	neutral	0,94	damaging	0,08	neutral	1,41	12,83	0,32	0,5	neutral	0,3	disease	0,9	disease	0,67	disease	0,7	4	neutral	0,93	deleterious	0,53	deleterious	2	deleterious	0,75	low_impact	-1,78	medium_impact	1,14	high_impact	2,86	0,3	0,8	58,42	8,65	N	0,32	N	0,92	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15116	15116	A	G	MI.9117	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	370	124	M	V	Ata/Gta	-20	0	0	probably_damaging	0,96	neutral	0,81	neutral	3,04	neutral	-1,38	deleterious	-3,56	high_impact	4,29	neutral	0,93	damaging	0,14	neutral	0,94	10,32	0,27	0,45	neutral	0,37	disease	0,9	disease	0,67	disease	0,69	4	neutral	0,95	neutral	0,43	deleterious	2	deleterious	0,8	low_impact	-2,02	medium_impact	0,56	high_impact	2,7	0,37	0,8	58,42	8,65	N	0,29	N	0,98	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15116	15116	A	T	MI.9118	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	370	124	M	L	Ata/Tta	-20	0	0	probably_damaging	0,93	neutral	0,98	neutral	3,24	neutral	0,33	deleterious	-2,67	high_impact	4,46	neutral	0,94	damaging	0,08	neutral	1,59	13,81	0,32	0,5	neutral	0,3	disease	0,9	disease	0,67	disease	0,7	4	neutral	0,93	deleterious	0,53	deleterious	2	deleterious	0,75	low_impact	-1,78	medium_impact	1,14	high_impact	2,86	0,3	0,8	58,42	8,65	N	0,32	N	0,92	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15117	15117	T	A	MI.9119	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	371	124	M	K	aTa/aAa	6,84	1	0	probably_damaging	0,98	neutral	0,09	neutral	2,91	deleterious	-3,97	deleterious	-5,35	high_impact	4,54	neutral	0,93	damaging	0,08	deleterious	2,08	16,72	0,04	0,35	disease	0,88	disease	0,95	disease	0,76	disease	0,65	3	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,9	low_impact	-2,31	medium_impact	-0,32	high_impact	2,93	0,15	0,8	58,42	8,65	P	0,64	P	0,99	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8955	8955	T	G	MI.912	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	429	143	I	M	atT/atG	3,83	0,45	0	probably_damaging	1	neutral	0,18	neutral	4,22	neutral	-2,18	neutral	-1,87	low_impact	1,28	neutral	0,9	neutral	0,95	deleterious	2,24	17,75	0,4	0,65	disease	0,62	neutral	0,23	neutral	0,38	disease	0,55	1	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	-0,08	medium_impact	0	0,74	0,9	19,47	13,18	N	0,49	N	0,73	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15117	15117	T	C	MI.9120	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	371	124	M	T	aTa/aCa	6,84	1	0	probably_damaging	0,99	neutral	0,45	neutral	2,95	neutral	-2,63	deleterious	-5,34	high_impact	4,75	neutral	0,93	damaging	0,11	neutral	1,24	11,94	0,09	0,35	disease	0,74	disease	0,89	disease	0,7	disease	0,69	4	deleterious	0,99	neutral	0,23	deleterious	2	deleterious	0,88	low_impact	-2,59	medium_impact	0,18	high_impact	3,12	0,16	0,8	58,42	8,65	P	0,7	P	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15118	15118	A	T	MI.9121	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	372	124	M	I	atA/atT	4,54	1	0	probably_damaging	0,97	neutral	0,4	neutral	3,03	neutral	-0,97	deleterious	-3,56	medium_impact	3,22	neutral	0,93	damaging	0,09	neutral	1,63	14,02	0,26	0,45	neutral	0,15	disease	0,9	disease	0,58	disease	0,53	1	neutral	0,97	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-2,14	medium_impact	0,13	medium_impact	1,73	0,38	0,8	58,42	8,65	N	0,46	N	0,95	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15118	15118	A	C	MI.9122	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	372	124	M	I	atA/atC	4,54	1	0	probably_damaging	0,97	neutral	0,4	neutral	3,03	neutral	-0,97	deleterious	-3,56	medium_impact	3,22	neutral	0,93	damaging	0,09	neutral	1,54	13,51	0,26	0,45	neutral	0,15	disease	0,9	disease	0,58	disease	0,53	1	neutral	0,97	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-2,14	medium_impact	0,13	medium_impact	1,73	0,38	0,8	58,42	8,65	N	0,44	N	0,95	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15119	15119	G	T	MI.9123	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	373	125	A	S	Gca/Tca	1,56	1	0,01	benign	0,26	neutral	0,22	neutral	3,01	neutral	-2,47	neutral	-1,8	high_impact	4,37	neutral	0,94	neutral	0,47	deleterious	3,29	22,8	0,23	0,45	disease	0,57	disease	0,86	disease	0,55	disease	0,63	3	neutral	0,74	deleterious	0,48	neutral	-2	neutral	0,33	medium_impact	-0,31	medium_impact	-0,08	high_impact	2,77	0,52	0,8	16,58	12,85	N	0,5	N	0,55	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15119	15119	G	C	MI.9124	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	373	125	A	P	Gca/Cca	1,56	1	0,01	possibly_damaging	0,66	neutral	0,23	neutral	2,96	deleterious	-4,51	deleterious	-3,32	high_impact	5,05	neutral	0,94	neutral	0,28	deleterious	3,63	23,2	0,03	0,35	disease	0,77	disease	0,94	disease	0,71	disease	0,76	5	neutral	0,8	neutral	0,29	deleterious	1	deleterious	0,79	medium_impact	-1	medium_impact	-0,06	high_impact	3,39	0,56	0,8	16,58	12,85	P	0,66	P	0,83	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15119	15119	G	A	MI.9125	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	373	125	A	T	Gca/Aca	1,56	1	0,01	benign	0,01	neutral	0,32	neutral	3,02	neutral	-2,13	neutral	-2,25	high_impact	3,56	neutral	0,96	neutral	0,52	deleterious	3,82	23,4	0,13	0,4	disease	0,5	disease	0,82	neutral	0,5	neutral	0,43	1	neutral	0,67	deleterious	0,66	neutral	-2	neutral	0,26	medium_impact	1,13	medium_impact	0,05	high_impact	2,04	0,61	0,8	16,58	12,85	P	0,51	P	0,32	polymorphism	1	0,03	rs201194402	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15120	15120	C	G	MI.9126	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	374	125	A	G	gCa/gGa	3,17	1	0	benign	0,16	neutral	0,34	neutral	3,16	neutral	-0,7	deleterious	-2,92	medium_impact	2,15	neutral	0,96	neutral	0,53	deleterious	2,11	16,9	0,2	0,45	disease	0,61	disease	0,82	neutral	0,37	neutral	0,2	6	neutral	0,6	deleterious	0,59	neutral	-3	neutral	0,33	medium_impact	-0,06	medium_impact	0,07	medium_impact	0,76	0,73	0,85	16,58	12,85	N	0,46	N	0,58	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15120	15120	C	A	MI.9127	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	374	125	A	E	gCa/gAa	3,17	1	0	possibly_damaging	0,68	neutral	0,13	neutral	2,97	deleterious	-3,91	deleterious	-3,31	high_impact	5,05	neutral	0,93	neutral	0,4	deleterious	4,34	24	0,04	0,35	disease	0,71	disease	0,94	disease	0,68	disease	0,75	5	neutral	0,89	neutral	0,23	deleterious	1	deleterious	0,68	low_impact	-1,04	medium_impact	-0,23	high_impact	3,39	0,39	0,8	16,58	12,85	P	0,68	P	0,87	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15120	15120	C	T	MI.9128	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	374	125	A	V	gCa/gTa	3,17	1	0	benign	0,18	neutral	0,42	neutral	3,12	neutral	-0,8	neutral	-1,95	medium_impact	3,04	neutral	0,95	neutral	0,5	deleterious	4	23,6	0,11	0,4	neutral	0,22	disease	0,88	neutral	0,41	neutral	0,18	6	neutral	0,5	deleterious	0,62	neutral	-3	neutral	0,35	medium_impact	-0,12	medium_impact	0,15	medium_impact	1,57	0,57	0,8	16,58	12,85	N	0,52	P	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15122	15122	A	G	MI.9129	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	376	126	T	A	Aca/Gca	-7,61	0	0	probably_damaging	0,99	neutral	0,57	neutral	3,14	neutral	-0,33	deleterious	-4,27	medium_impact	3,25	neutral	0,9	neutral	0,57	neutral	1,7	14,4	0,12	0,4	disease	0,55	disease	0,7	neutral	0,49	neutral	0,45	1	deleterious	0,99	neutral	0,29	deleterious	1	neutral	0,21	low_impact	-2,59	medium_impact	0,29	medium_impact	1,76	0,3	0,8	55,79	8,73	N	0,27	N	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8956	8956	A	T	MI.913	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	430	144	I	F	Atc/Ttc	-4,27	0	0	probably_damaging	0,99	deleterious	0	neutral	3,9	deleterious	-5,06	deleterious	-3,68	high_impact	3,83	neutral	0,78	damaging	0,12	deleterious	3,79	23,4	0,25	0,65	disease	0,73	disease	0,71	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,65	low_impact	-1,4	high_impact	2,19	0,74	0,9	49,12	8,59	N	0,31	N	0,97	disease_causing	0,98	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15122	15122	A	T	MI.9130	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	376	126	T	S	Aca/Tca	-7,61	0	0	probably_damaging	0,99	neutral	0,39	neutral	3,03	neutral	-2,02	deleterious	-3,44	high_impact	3,73	neutral	0,93	neutral	0,49	neutral	1,72	14,5	0,21	0,45	disease	0,59	disease	0,75	disease	0,57	disease	0,64	3	deleterious	0,99	neutral	0,2	deleterious	2	neutral	0,28	low_impact	-2,59	medium_impact	0,12	high_impact	2,19	0,41	0,8	55,79	8,73	N	0,37	N	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15122	15122	A	C	MI.9131	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	376	126	T	P	Aca/Cca	-7,61	0	0	probably_damaging	1	neutral	0,22	neutral	2,97	deleterious	-3,66	deleterious	-5,19	high_impact	5,39	neutral	0,93	neutral	0,32	deleterious	3,3	22,9	0,05	0,35	disease	0,83	disease	0,86	disease	0,75	disease	0,66	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,71	low_impact	-3,53	medium_impact	-0,08	high_impact	3,7	0,28	0,8	55,79	8,73	P	0,72	P	0,95	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15123	15123	C	A	MI.9132	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	377	126	T	K	aCa/aAa	8,44	1	0	probably_damaging	1	neutral	0,28	neutral	3,02	neutral	-2,3	deleterious	-5,2	high_impact	5,39	neutral	0,94	neutral	0,37	deleterious	4,15	23,8	0,08	0,35	disease	0,68	disease	0,9	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,62	low_impact	-3,53	medium_impact	0	high_impact	3,7	0,34	0,8	55,79	8,73	P	0,79	P	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15123	15123	C	T	MI.9133	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	377	126	T	M	aCa/aTa	8,44	1	0	probably_damaging	1	neutral	0,26	neutral	3,01	neutral	-1,73	deleterious	-5,2	high_impact	5,05	neutral	0,94	neutral	0,44	deleterious	3,85	23,4	0,09	0,35	disease	0,86	disease	0,86	disease	0,66	disease	0,63	3	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	-0,02	high_impact	3,39	0,37	0,8	55,79	8,73	P	0,75	P	0,96	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15125	15125	G	A	MI.9134	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	379	127	A	T	Gcc/Acc	-5,32	0	0	probably_damaging	1	neutral	0,48	neutral	2,74	deleterious	-3,64	deleterious	-3,49	high_impact	4,92	neutral	0,96	damaging	0,13	deleterious	4,07	23,7	0,09	0,35	disease	0,76	disease	0,81	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,2	high_impact	3,27	0,8	0,85	57,63	8,8	P	0,69	P	0,79	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15125	15125	G	T	MI.9135	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	379	127	A	S	Gcc/Tcc	-5,32	0	0	probably_damaging	1	neutral	0,41	neutral	2,95	neutral	-1,23	deleterious	-2,62	high_impact	4	neutral	0,94	damaging	0,1	deleterious	3,53	23,1	0,15	0,4	disease	0,7	disease	0,81	disease	0,58	disease	0,65	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,14	high_impact	2,44	0,56	0,8	57,63	8,8	N	0,32	N	0,91	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15125	15125	G	C	MI.9136	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	379	127	A	P	Gcc/Ccc	-5,32	0	0	probably_damaging	1	neutral	0,21	neutral	2,71	deleterious	-5,16	deleterious	-4,37	high_impact	5,47	neutral	0,95	damaging	0,05	deleterious	3,73	23,3	0,03	0,35	disease	0,88	disease	0,87	disease	0,76	disease	0,61	2	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,09	high_impact	3,77	0,52	0,8	57,63	8,8	P	0,72	P	0,98	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15126	15126	C	T	MI.9137	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	380	127	A	V	gCc/gTc	5,92	1	0	probably_damaging	1	neutral	0,52	neutral	2,76	deleterious	-3,03	deleterious	-3,49	high_impact	4,92	neutral	0,97	damaging	0,13	deleterious	4,27	24	0,07	0,35	disease	0,85	disease	0,85	disease	0,6	disease	0,62	2	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,24	high_impact	3,27	0,75	0,85	57,63	8,8	P	0,78	P	0,84	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15126	15126	C	G	MI.9138	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	380	127	A	G	gCc/gGc	5,92	1	0	probably_damaging	1	neutral	0,35	neutral	3,16	neutral	-0,08	deleterious	-3,49	high_impact	3,77	neutral	0,95	damaging	0,14	deleterious	3,61	23,2	0,14	0,4	disease	0,66	disease	0,77	disease	0,57	disease	0,65	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,08	high_impact	2,23	0,63	0,8	57,63	8,8	N	0,53	P	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15126	15126	C	A	MI.9139	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	380	127	A	D	gCc/gAc	5,92	1	0	probably_damaging	1	neutral	0,2	neutral	2,71	deleterious	-5,15	deleterious	-5,24	high_impact	5,47	neutral	0,93	damaging	0,08	deleterious	4,54	24,3	0,03	0,35	disease	0,91	disease	0,91	disease	0,74	disease	0,62	2	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,1	high_impact	3,77	0,29	0,8	57,63	8,8	P	0,76	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8956	8956	A	G	MI.914	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	430	144	I	V	Atc/Gtc	-4,27	0	0	probably_damaging	0,93	neutral	0,14	neutral	3,99	neutral	-2,84	neutral	-0,92	medium_impact	2,08	neutral	0,85	damaging	0,21	deleterious	3,03	22,3	0,46	0,65	disease	0,64	neutral	0,39	disease	0,62	disease	0,57	1	neutral	0,97	neutral	0,11	deleterious	1	deleterious	0,68	low_impact	-1,82	medium_impact	-0,15	medium_impact	0,69	0,63	0,9	49,12	8,59	N	0,34	N	0,77	polymorphism	0,84	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15128	15128	T	C	MI.9140	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	382	128	F	L	Ttc/Ctc	-6,93	0	0	benign	0,01	neutral	0,66	neutral	2,77	deleterious	-3,54	deleterious	-5,25	high_impact	4	neutral	0,95	damaging	0,11	deleterious	3,59	23,2	0,08	0,35	neutral	0,49	disease	0,79	disease	0,68	disease	0,66	3	neutral	0,31	deleterious	0,83	neutral	-2	neutral	0,24	medium_impact	1,13	medium_impact	0,38	high_impact	2,44	0,51	0,8	58,16	8,74	N	0,23	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15128	15128	T	G	MI.9141	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	382	128	F	V	Ttc/Gtc	-6,93	0	0	possibly_damaging	0,55	neutral	0,51	neutral	2,8	deleterious	-4,18	deleterious	-6,13	high_impact	4,8	neutral	0,95	damaging	0,11	deleterious	3,97	23,6	0,08	0,35	disease	0,79	disease	0,84	disease	0,74	disease	0,69	4	neutral	0,53	deleterious	0,48	deleterious	1	deleterious	0,59	medium_impact	-0,81	medium_impact	0,23	high_impact	3,17	0,26	0,8	58,16	8,74	P	0,6	P	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15128	15128	T	A	MI.9142	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	382	128	F	I	Ttc/Atc	-6,93	0	0	benign	0,25	neutral	0,4	neutral	2,77	deleterious	-3,86	deleterious	-5,25	high_impact	5,5	neutral	0,94	damaging	0,12	deleterious	4,13	23,8	0,08	0,35	disease	0,76	disease	0,83	disease	0,71	disease	0,67	3	neutral	0,52	deleterious	0,58	neutral	-2	deleterious	0,54	medium_impact	-0,29	medium_impact	0,13	high_impact	3,8	0,36	0,8	58,16	8,74	P	0,59	P	0,97	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15129	15129	T	A	MI.9143	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	383	128	F	Y	tTc/tAc	7,3	1	0	possibly_damaging	0,6	neutral	1	neutral	2,7	deleterious	-3,28	deleterious	-2,63	high_impact	5,5	neutral	0,95	damaging	0,11	deleterious	3,76	23,3	0,1	0,4	disease	0,62	disease	0,76	disease	0,71	disease	0,68	4	neutral	0,6	deleterious	0,7	deleterious	1	deleterious	0,67	medium_impact	-0,9	high_impact	1,85	high_impact	3,8	0,48	0,8	58,16	8,74	P	0,7	P	0,87	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15129	15129	T	C	MI.9144	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	383	128	F	S	tTc/tCc	7,3	1	0	possibly_damaging	0,9	neutral	0,4	neutral	2,67	deleterious	-6,5	deleterious	-7,01	high_impact	4,69	neutral	0,93	damaging	0,08	deleterious	4,09	23,7	0,03	0,35	disease	0,91	disease	0,82	disease	0,72	disease	0,62	2	neutral	0,9	neutral	0,25	deleterious	1	deleterious	0,8	low_impact	-1,62	medium_impact	0,13	high_impact	3,07	0,27	0,8	58,16	8,74	P	0,64	P	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15129	15129	T	G	MI.9145	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	383	128	F	C	tTc/tGc	7,3	1	0	probably_damaging	0,98	neutral	0,17	neutral	2,64	deleterious	-7,74	deleterious	-7,01	high_impact	5,5	neutral	0,95	damaging	0,09	deleterious	4,02	23,6	0,04	0,35	disease	0,96	disease	0,85	disease	0,76	disease	0,64	3	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-2,31	medium_impact	-0,15	high_impact	3,8	0,26	0,8	58,16	8,74	P	0,66	P	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15130	15130	C	A	MI.9146	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	384	128	F	L	ttC/ttA	5,69	1	0,01	benign	0,01	neutral	0,66	neutral	2,77	deleterious	-3,54	deleterious	-5,25	high_impact	4	neutral	0,95	damaging	0,11	deleterious	4,24	23,9	0,08	0,35	neutral	0,49	disease	0,79	disease	0,68	disease	0,66	3	neutral	0,31	deleterious	0,83	neutral	-2	neutral	0,24	medium_impact	1,13	medium_impact	0,38	high_impact	2,44	0,51	0,8	58,16	8,74	N	0,49	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15130	15130	C	G	MI.9147	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	384	128	F	L	ttC/ttG	5,69	1	0,01	benign	0,01	neutral	0,66	neutral	2,77	deleterious	-3,54	deleterious	-5,25	high_impact	4	neutral	0,95	damaging	0,11	deleterious	3,87	23,5	0,08	0,35	neutral	0,49	disease	0,79	disease	0,68	disease	0,66	3	neutral	0,31	deleterious	0,83	neutral	-2	neutral	0,24	medium_impact	1,13	medium_impact	0,38	high_impact	2,44	0,51	0,8	58,16	8,74	N	0,49	N	0,92	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15131	15131	A	C	MI.9148	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	385	129	M	L	Ata/Cta	-2,8	0	0	probably_damaging	0,96	neutral	0,69	neutral	3,35	neutral	0,82	neutral	-0,76	neutral_impact	0,33	neutral	0,94	neutral	0,4	deleterious	0,33	5,97	0,19	0,45	neutral	0,14	disease	0,81	neutral	0,45	neutral	0,19	6	neutral	0,95	neutral	0,37	neutral	-2	deleterious	0,67	low_impact	-2,02	medium_impact	0,41	medium_impact	-0,89	0,22	0,8	38,68	11,42	N	0,21	N	0,78	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15131	15131	A	G	MI.9149	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	385	129	M	V	Ata/Gta	-2,8	0	0	probably_damaging	0,98	neutral	0,77	neutral	3,23	neutral	-0,13	neutral	0,24	neutral_impact	-0,28	neutral	0,98	neutral	0,67	neutral	-1,2	0,01	0,18	0,45	neutral	0,24	neutral	0,2	neutral	0,45	neutral	0,34	3	neutral	0,97	neutral	0,4	neutral	-2	deleterious	0,66	low_impact	-2,31	medium_impact	0,51	low_impact	-1,45	0,23	0,8	38,68	11,42	N	0,33	N	0,51	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8956	8956	A	C	MI.915	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	430	144	I	L	Atc/Ctc	-4,27	0	0	probably_damaging	0,93	neutral	0,06	neutral	4,34	neutral	-1,96	neutral	-1,84	medium_impact	3,08	neutral	0,8	damaging	0,12	deleterious	3,83	23,4	0,3	0,65	neutral	0,25	disease	0,58	disease	0,65	disease	0,65	3	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,63	low_impact	-1,82	medium_impact	-0,38	medium_impact	1,54	0,66	0,9	49,12	8,59	N	0,33	N	0,83	polymorphism	0,69	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15131	15131	A	T	MI.9150	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	385	129	M	L	Ata/Tta	-2,8	0	0	probably_damaging	0,96	neutral	0,69	neutral	3,35	neutral	0,82	neutral	-0,76	neutral_impact	0,33	neutral	0,94	neutral	0,4	deleterious	0,4	6,57	0,19	0,45	neutral	0,14	disease	0,81	neutral	0,45	neutral	0,19	6	neutral	0,95	neutral	0,37	neutral	-2	deleterious	0,67	low_impact	-2,02	medium_impact	0,41	medium_impact	-0,89	0,22	0,8	38,68	11,42	N	0,21	N	0,78	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15132	15132	T	A	MI.9151	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	386	129	M	K	aTa/aAa	0,87	0,74	0	probably_damaging	0,99	neutral	0,24	neutral	3,09	neutral	-2,38	deleterious	-3,6	high_impact	4,27	neutral	0,93	neutral	0,37	deleterious	2,21	17,56	0,03	0,35	disease	0,7	disease	0,92	disease	0,77	disease	0,74	5	deleterious	0,99	neutral	0,13	deleterious	2	deleterious	0,87	low_impact	-2,59	medium_impact	-0,05	high_impact	2,68	0,15	0,8	38,68	11,42	N	0,49	N	0,98	disease_causing	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15132	15132	T	C	MI.9152	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	386	129	M	T	aTa/aCa	0,87	0,74	0	probably_damaging	1	neutral	0,35	neutral	3,27	neutral	1,74	deleterious	-2,51	medium_impact	2,92	neutral	0,9	neutral	0,49	deleterious	2,51	19,53	0,08	0,35	disease	0,51	disease	0,82	disease	0,63	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,82	low_impact	-3,53	medium_impact	0,08	medium_impact	1,46	0,18	0,8	38,68	11,42	N	0,32	N	0,88	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15133	15133	A	C	MI.9153	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	387	129	M	I	atA/atC	7,3	0,98	0	probably_damaging	0,98	neutral	0,41	neutral	3,16	neutral	-0,33	neutral	-0,19	medium_impact	2,4	neutral	0,96	neutral	0,43	neutral	1,61	13,89	0,21	0,45	neutral	0,19	disease	0,85	disease	0,54	disease	0,51	0	deleterious	0,98	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-2,31	medium_impact	0,14	medium_impact	0,99	0,28	0,8	38,68	11,42	N	0,54	P	0,88	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15133	15133	A	T	MI.9154	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	387	129	M	I	atA/atT	7,3	0,98	0	probably_damaging	0,98	neutral	0,41	neutral	3,16	neutral	-0,33	neutral	-0,19	medium_impact	2,4	neutral	0,96	neutral	0,43	neutral	1,73	14,6	0,21	0,45	neutral	0,19	disease	0,85	disease	0,54	disease	0,51	0	deleterious	0,98	neutral	0,22	deleterious	1	deleterious	0,75	low_impact	-2,31	medium_impact	0,14	medium_impact	0,99	0,28	0,8	38,68	11,42	P	0,57	P	0,88	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15134	15134	G	A	MI.9155	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	388	130	G	S	Ggc/Agc	-4,86	0	0	probably_damaging	1	neutral	0,4	neutral	1,12	deleterious	-8,62	deleterious	-5,2	high_impact	4,7	neutral	0,82	damaging	0,05	deleterious	4,06	23,7	0,04	0,35	disease	0,92	disease	0,82	disease	0,67	disease	0,61	2	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,13	high_impact	3,07	0,68	0,85	58,68	8,89	N	0,54	P	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15134	15134	G	T	MI.9156	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	388	130	G	C	Ggc/Tgc	-4,86	0	0	probably_damaging	1	neutral	0,18	neutral	1,08	deleterious	-11,62	deleterious	-7,8	high_impact	5,5	neutral	0,84	damaging	0,03	deleterious	4,02	23,6	0,02	0,35	disease	0,97	disease	0,9	disease	0,68	disease	0,65	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,14	high_impact	3,8	0,24	0,8	58,68	8,89	N	0,51	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15134	15134	G	C	MI.9157	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	388	130	G	R	Ggc/Cgc	-4,86	0	0	probably_damaging	1	neutral	0,35	neutral	1,08	deleterious	-10,01	deleterious	-6,94	high_impact	4,8	neutral	0,83	damaging	0,04	deleterious	3,8	23,4	0,02	0,35	disease	0,96	disease	0,9	disease	0,77	disease	0,6	2	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,08	high_impact	3,17	0,58	0,8	58,68	8,89	P	0,63	P	0,99	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15135	15135	G	C	MI.9158	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	389	130	G	A	gGc/gCc	7,3	1	0	probably_damaging	1	neutral	0,51	neutral	1,13	deleterious	-7,45	deleterious	-5,2	high_impact	4,95	neutral	0,84	damaging	0,1	deleterious	2,97	22,1	0,04	0,35	disease	0,9	disease	0,72	disease	0,65	disease	0,64	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,23	high_impact	3,3	0,51	0,8	58,68	8,89	P	0,7	P	0,83	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15135	15135	G	T	MI.9159	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	389	130	G	V	gGc/gTc	7,3	1	0	probably_damaging	1	neutral	0,5	neutral	1,09	deleterious	-10,85	deleterious	-7,8	high_impact	5,15	neutral	0,84	damaging	0,07	deleterious	3,66	23,2	0,02	0,35	disease	0,96	disease	0,88	disease	0,68	disease	0,6	2	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,22	high_impact	3,48	0,23	0,8	58,68	8,89	P	0,6	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8957	8957	T	A	MI.916	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	431	144	I	N	aTc/aAc	8,69	1	0	probably_damaging	1	deleterious	0,02	neutral	3,82	deleterious	-7,57	deleterious	-6,44	high_impact	4,17	neutral	0,86	damaging	0,15	deleterious	4,37	24,1	0,2	0,65	disease	0,98	disease	0,73	disease	0,72	disease	0,83	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-3,6	medium_impact	-0,66	high_impact	2,48	0,48	0,9	49,12	8,59	P	0,53	P	1	disease_causing	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15135	15135	G	A	MI.9160	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	389	130	G	D	gGc/gAc	7,3	1	0	probably_damaging	1	neutral	0,2	neutral	1,09	deleterious	-9,22	deleterious	-6,07	high_impact	4,61	neutral	0,79	damaging	0,05	deleterious	3,77	23,4	0,02	0,35	disease	0,95	disease	0,88	disease	0,76	disease	0,61	2	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,1	high_impact	2,99	0,17	0,8	58,68	8,89	P	0,54	P	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15137	15137	T	A	MI.9161	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	391	131	Y	N	Tat/Aat	-12,2	0	0	probably_damaging	1	neutral	0,3	neutral	2,53	deleterious	-6,76	deleterious	-7,79	high_impact	4,36	neutral	0,86	damaging	0,09	deleterious	3,9	23,5	0,06	0,35	disease	0,94	disease	0,85	disease	0,72	disease	0,62	2	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,02	high_impact	2,77	0,12	0,8	56,84	8,83	N	0,43	N	0,99	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15137	15137	T	G	MI.9162	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	391	131	Y	D	Tat/Gat	-12,2	0	0	probably_damaging	1	neutral	0,2	neutral	2,54	deleterious	-7,62	deleterious	-8,66	high_impact	5,16	neutral	0,84	damaging	0,07	deleterious	3,83	23,4	0,03	0,35	disease	0,96	disease	0,87	disease	0,8	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,1	high_impact	3,49	0,2	0,8	56,84	8,83	P	0,61	P	1	disease_causing	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15137	15137	T	C	MI.9163	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	391	131	Y	H	Tat/Cat	-12,2	0	0	probably_damaging	1	neutral	0,53	neutral	2,52	deleterious	-5,71	deleterious	-4,33	high_impact	4,81	neutral	0,9	damaging	0,08	deleterious	3,38	22,9	0,13	0,4	disease	0,9	disease	0,8	disease	0,79	disease	0,66	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,25	high_impact	3,17	0,18	0,8	56,84	8,83	P	0,67	P	0,98	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15138	15138	A	G	MI.9164	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	392	131	Y	C	tAt/tGt	5,69	1	0	probably_damaging	1	neutral	0,17	neutral	2,51	deleterious	-7,62	deleterious	-7,8	high_impact	5,5	neutral	0,86	damaging	0,05	deleterious	3,46	23	0,05	0,35	disease	0,97	disease	0,88	disease	0,76	disease	0,65	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,15	high_impact	3,8	0,14	0,8	56,84	8,83	P	0,63	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15138	15138	A	C	MI.9165	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	392	131	Y	S	tAt/tCt	5,69	1	0	probably_damaging	1	neutral	0,4	neutral	2,55	deleterious	-6,69	deleterious	-7,79	high_impact	5,16	neutral	0,89	damaging	0,09	deleterious	3,62	23,2	0,06	0,35	disease	0,93	disease	0,84	disease	0,71	disease	0,63	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,13	high_impact	3,49	0,2	0,8	56,84	8,83	P	0,66	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15138	15138	A	T	MI.9166	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	392	131	Y	F	tAt/tTt	5,69	1	0	probably_damaging	0,99	neutral	0,69	neutral	2,54	deleterious	-4,03	deleterious	-3,46	high_impact	5,16	neutral	0,91	damaging	0,08	neutral	1,73	14,58	0,14	0,4	disease	0,7	disease	0,82	disease	0,67	disease	0,66	3	deleterious	0,99	neutral	0,35	deleterious	2	deleterious	0,83	low_impact	-2,59	medium_impact	0,41	high_impact	3,49	0,43	0,8	56,84	8,83	P	0,73	P	0,83	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15140	15140	G	A	MI.9167	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	394	132	V	I	Gtc/Atc	-5,78	0	0,01	probably_damaging	0,99	neutral	0,31	neutral	3	neutral	-1,17	neutral	-0,8	medium_impact	2,68	neutral	0,82	neutral	0,53	deleterious	1,85	15,31	0,37	0,5	neutral	0,4	disease	0,64	neutral	0,44	neutral	0,34	3	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,7	low_impact	-2,59	medium_impact	0,03	medium_impact	1,24	0,83	0,85	55,53	8,57	N	0,33	N	0,34	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15140	15140	G	T	MI.9168	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	394	132	V	F	Gtc/Ttc	-5,78	0	0,01	probably_damaging	1	neutral	0,7	neutral	2,89	deleterious	-3,05	deleterious	-4,24	high_impact	4,75	neutral	0,9	neutral	0,43	deleterious	3,71	23,3	0,02	0,35	disease	0,81	disease	0,88	disease	0,6	disease	0,64	3	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,42	high_impact	3,12	0,35	0,8	55,53	8,57	P	0,62	P	0,98	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15140	15140	G	C	MI.9169	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	394	132	V	L	Gtc/Ctc	-5,78	0	0,01	probably_damaging	0,99	neutral	0,6	neutral	3	neutral	-1,22	deleterious	-2,51	high_impact	4,16	neutral	0,92	neutral	0,41	neutral	1,76	14,75	0,12	0,4	neutral	0,45	disease	0,72	disease	0,56	disease	0,63	3	deleterious	0,99	neutral	0,31	deleterious	2	deleterious	0,77	low_impact	-2,59	medium_impact	0,32	high_impact	2,58	0,42	0,8	55,53	8,57	N	0,29	N	0,69	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8957	8957	T	G	MI.917	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	431	144	I	S	aTc/aGc	8,69	1	0	probably_damaging	0,99	deleterious	0,02	neutral	3,83	deleterious	-6,41	deleterious	-5,49	high_impact	4,52	neutral	0,85	damaging	0,18	deleterious	4,25	23,9	0,2	0,65	disease	0,96	disease	0,78	disease	0,69	disease	0,81	6	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-2,65	medium_impact	-0,66	high_impact	2,78	0,52	0,9	49,12	8,59	P	0,53	P	0,98	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15141	15141	T	A	MI.9170	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	395	132	V	D	gTc/gAc	5,92	1	0	probably_damaging	1	neutral	0,16	neutral	2,86	deleterious	-4,91	deleterious	-6	high_impact	5,09	neutral	0,86	neutral	0,4	deleterious	4,35	24,1	0,01	0,35	disease	0,94	disease	0,85	disease	0,75	disease	0,65	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,17	high_impact	3,43	0,2	0,8	55,53	8,57	P	0,7	P	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15141	15141	T	C	MI.9171	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	395	132	V	A	gTc/gCc	5,92	1	0	probably_damaging	1	neutral	0,47	neutral	2,92	neutral	-2,3	deleterious	-3,41	high_impact	5,44	neutral	0,92	neutral	0,5	deleterious	3,31	22,9	0,05	0,35	disease	0,71	disease	0,64	disease	0,65	disease	0,65	3	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	0,19	high_impact	3,75	0,2	0,8	55,53	8,57	P	0,75	P	0,62	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15141	15141	T	G	MI.9172	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	395	132	V	G	gTc/gGc	5,92	1	0	probably_damaging	1	neutral	0,42	neutral	2,87	deleterious	-4,01	deleterious	-6,02	high_impact	5,09	neutral	0,91	neutral	0,47	deleterious	3,72	23,3	0,02	0,35	disease	0,9	disease	0,75	disease	0,68	disease	0,64	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,15	high_impact	3,43	0,29	0,8	55,53	8,57	P	0,71	P	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15143	15143	C	A	MI.9173	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	397	133	L	I	Ctc/Atc	-8,76	0	0	probably_damaging	1	neutral	0,37	neutral	1,27	deleterious	-5,76	neutral	-1,73	high_impact	4,96	neutral	0,87	damaging	0,06	deleterious	3,92	23,5	0,19	0,45	disease	0,59	disease	0,76	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,1	high_impact	3,31	0,57	0,8	56,84	8,46	P	0,67	P	0,86	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15143	15143	C	T	MI.9174	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	397	133	L	F	Ctc/Ttc	-8,76	0	0	probably_damaging	1	neutral	0,75	neutral	1,24	deleterious	-6,83	deleterious	-3,46	high_impact	4,7	neutral	0,91	damaging	0,05	deleterious	3,85	23,4	0,11	0,4	disease	0,75	disease	0,75	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,48	high_impact	3,07	0,63	0,8	56,84	8,46	N	0,48	N	0,97	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15143	15143	C	G	MI.9175	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	397	133	L	V	Ctc/Gtc	-8,76	0	0	probably_damaging	0,99	neutral	0,76	neutral	1,25	deleterious	-6,35	deleterious	-2,6	high_impact	5,16	neutral	0,81	damaging	0,08	deleterious	3,09	22,5	0,14	0,4	disease	0,58	disease	0,68	disease	0,73	disease	0,68	4	deleterious	0,99	neutral	0,39	deleterious	2	deleterious	0,77	low_impact	-2,59	medium_impact	0,49	high_impact	3,49	0,5	0,8	56,84	8,46	P	0,6	P	0,91	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15144	15144	T	C	MI.9176	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	398	133	L	P	cTc/cCc	1,33	0,72	0	probably_damaging	1	neutral	0,28	neutral	1,2	deleterious	-10,13	deleterious	-6,06	high_impact	4,7	neutral	0,86	damaging	0,03	deleterious	3,83	23,4	0,02	0,35	disease	0,76	disease	0,8	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0	high_impact	3,07	0,28	0,8	56,84	8,46	N	0,49	N	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15144	15144	T	G	MI.9177	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	398	133	L	R	cTc/cGc	1,33	0,72	0	probably_damaging	1	neutral	0,31	neutral	1,2	deleterious	-9,79	deleterious	-5,2	high_impact	5,51	neutral	0,83	damaging	0,03	deleterious	4,1	23,7	0,01	0,35	disease	0,86	disease	0,9	disease	0,81	disease	0,7	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,03	high_impact	3,81	0,27	0,8	56,84	8,46	P	0,67	P	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15144	15144	T	A	MI.9178	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	398	133	L	H	cTc/cAc	1,33	0,72	0	probably_damaging	1	neutral	0,48	neutral	1,2	deleterious	-10,71	deleterious	-6,06	high_impact	5,51	neutral	0,88	damaging	0,06	deleterious	4,07	23,7	0,02	0,35	disease	0,91	disease	0,8	disease	0,79	disease	0,69	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,2	high_impact	3,81	0,32	0,8	56,84	8,46	P	0,62	P	0,95	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15146	15146	C	G	MI.9179	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	400	134	P	A	Ccg/Gcg	-9,45	0	0	probably_damaging	1	neutral	0,56	neutral	2,87	deleterious	-4,32	deleterious	-6,89	high_impact	5,14	neutral	0,94	neutral	0,51	deleterious	2,74	21	0,13	0,4	disease	0,56	disease	0,74	disease	0,72	disease	0,67	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	0,28	high_impact	3,47	0,63	0,8	58,95	8,8	P	0,58	P	0,84	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8957	8957	T	C	MI.918	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	431	144	I	T	aTc/aCc	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	3,84	deleterious	-5,71	deleterious	-4,56	high_impact	3,97	neutral	0,93	damaging	0,17	deleterious	3,43	23	0,33	0,65	disease	0,93	disease	0,66	disease	0,69	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,65	low_impact	-1,4	high_impact	2,3	0,61	0,9	49,12	8,59	N	0,53	P	0,99	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15146	15146	C	T	MI.9180	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	400	134	P	S	Ccg/Tcg	-9,45	0	0	probably_damaging	1	neutral	0,42	neutral	2,87	deleterious	-4,81	deleterious	-6,89	high_impact	4,94	neutral	0,93	neutral	0,47	deleterious	3,77	23,4	0,12	0,4	disease	0,65	disease	0,82	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,15	high_impact	3,29	0,16	0,8	58,95	8,8	P	0,64	P	0,9	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15146	15146	C	A	MI.9181	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	400	134	P	T	Ccg/Acg	-9,45	0	0	probably_damaging	1	neutral	0,39	neutral	2,85	deleterious	-4,98	deleterious	-6,89	high_impact	4,8	neutral	0,92	neutral	0,45	deleterious	3,54	23,1	0,11	0,4	disease	0,7	disease	0,83	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,12	high_impact	3,17	0,54	0,8	58,95	8,8	P	0,62	P	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15147	15147	C	G	MI.9182	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	401	134	P	R	cCg/cGg	5,46	1	0	probably_damaging	1	neutral	0,34	neutral	2,85	deleterious	-5,36	deleterious	-7,76	high_impact	5,49	neutral	0,93	neutral	0,37	deleterious	3,54	23,1	0,05	0,35	disease	0,85	disease	0,91	disease	0,81	disease	0,67	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,07	high_impact	3,79	0,35	0,8	58,95	8,8	P	0,7	P	0,8	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15147	15147	C	A	MI.9183	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	401	134	P	Q	cCg/cAg	5,46	1	0	probably_damaging	1	neutral	0,31	neutral	2,81	deleterious	-5,96	deleterious	-6,89	high_impact	5,49	neutral	0,93	neutral	0,39	deleterious	4,04	23,7	0,08	0,35	disease	0,87	disease	0,85	disease	0,73	disease	0,63	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,03	high_impact	3,79	0,33	0,8	58,95	8,8	P	0,71	P	0,86	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15147	15147	C	T	MI.9184	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	401	134	P	L	cCg/cTg	5,46	1	0	probably_damaging	1	neutral	0,73	neutral	2,87	deleterious	-4,6	deleterious	-8,62	high_impact	4,68	neutral	0,91	neutral	0,38	deleterious	4,32	24	0,06	0,35	disease	0,73	disease	0,87	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,46	high_impact	3,06	0,57	0,8	58,95	8,8	P	0,62	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15149	15149	T	G	MI.9185	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	403	135	W	G	Tga/Gga	-0,96	0,02	0	probably_damaging	1	neutral	0,39	neutral	3,13	neutral	-2,37	deleterious	-10,53	high_impact	4,96	neutral	0,8	damaging	0,13	deleterious	3,81	23,4	0,05	0,35	disease	0,91	disease	0,85	disease	0,82	disease	0,63	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,12	high_impact	3,31	0,14	0,8	56,32	8,6	P	0,68	P	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15149	15149	T	C	MI.9186	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	403	135	W	R	Tga/Cga	-0,96	0,02	0	probably_damaging	1	neutral	0,33	neutral	3,01	deleterious	-3,75	deleterious	-11,34	high_impact	5,16	neutral	0,82	damaging	0,07	deleterious	3,46	23	0,05	0,35	disease	0,9	disease	0,93	disease	0,84	disease	0,63	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,06	high_impact	3,49	0,15	0,8	56,32	8,6	P	0,65	P	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15150	15150	G	C	MI.9187	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	404	135	W	S	tGa/tCa	7,3	1	0	probably_damaging	1	neutral	0,42	neutral	3,06	neutral	-2,72	deleterious	-11,34	high_impact	4,61	neutral	0,79	damaging	0,1	deleterious	3,9	23,5	0,05	0,35	disease	0,85	disease	0,91	disease	0,81	disease	0,66	3	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,15	high_impact	2,99	0,12	0,8	56,32	8,6	P	0,6	P	0,99	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15150	15150	G	T	MI.9188	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	404	135	W	L	tGa/tTa	7,3	1	0	probably_damaging	1	neutral	0,69	neutral	3,09	neutral	-2,37	deleterious	-10,53	high_impact	4,96	neutral	0,8	damaging	0,08	deleterious	4,2	23,9	0,06	0,35	disease	0,69	disease	0,86	disease	0,81	disease	0,71	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,41	high_impact	3,31	0,08	0,8	56,32	8,6	P	0,71	P	0,99	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15151	15151	A	C	MI.9189	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	405	135	W	C	tgA/tgC	8,9	1	0	probably_damaging	1	neutral	0,17	neutral	3,02	deleterious	-5,17	deleterious	-10,53	high_impact	5,5	neutral	0,83	damaging	0,05	deleterious	3,94	23,5	0,05	0,35	disease	0,93	disease	0,92	disease	0,85	disease	0,66	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,15	high_impact	3,8	0,19	0,8	56,32	8,6	P	0,65	P	1	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8958	8958	C	G	MI.919	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	432	144	I	M	atC/atG	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	3,92	deleterious	-4,95	deleterious	-2,76	high_impact	3,83	neutral	0,83	damaging	0,15	deleterious	3,39	23	0,32	0,65	disease	0,76	disease	0,59	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-3,6	medium_impact	-0,84	high_impact	2,19	0,75	0,9	49,12	8,59	P	0,5	N	0,75	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15151	15151	A	T	MI.9190	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	405	135	W	C	tgA/tgT	8,9	1	0	probably_damaging	1	neutral	0,17	neutral	3,02	deleterious	-5,17	deleterious	-10,53	high_impact	5,5	neutral	0,83	damaging	0,05	deleterious	4,06	23,7	0,05	0,35	disease	0,93	disease	0,92	disease	0,85	disease	0,66	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,15	high_impact	3,8	0,19	0,8	56,32	8,6	P	0,65	P	1	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15152	15152	G	T	MI.9191	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	406	136	G	C	Ggc/Tgc	2,48	1	0	probably_damaging	1	neutral	0,17	neutral	3,03	deleterious	-6,3	deleterious	-7,32	high_impact	5,5	neutral	0,91	damaging	0,23	deleterious	4,18	23,8	0,03	0,35	disease	0,9	disease	0,93	disease	0,73	disease	0,64	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,15	high_impact	3,8	0,16	0,8	58,68	8,75	P	0,65	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15152	15152	G	A	MI.9192	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	406	136	G	S	Ggc/Agc	2,48	1	0	probably_damaging	1	neutral	0,44	neutral	3,09	neutral	-1,93	deleterious	-4,87	high_impact	4,12	neutral	0,9	neutral	0,34	deleterious	4,12	23,8	0,05	0,35	disease	0,66	disease	0,86	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,17	high_impact	2,55	0,32	0,8	58,68	8,75	P	0,55	P	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15152	15152	G	C	MI.9193	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	406	136	G	R	Ggc/Cgc	2,48	1	0	probably_damaging	1	neutral	0,34	neutral	3,07	deleterious	-3,05	deleterious	-6,5	high_impact	5,5	neutral	0,9	damaging	0,24	deleterious	3,94	23,6	0,05	0,35	disease	0,88	disease	0,93	disease	0,82	disease	0,65	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0,07	high_impact	3,8	0,28	0,8	58,68	8,75	P	0,7	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15153	15153	G	A	MI.9194	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	407	136	G	D	gGc/gAc	7,07	1	0	probably_damaging	1	neutral	0,2	neutral	3,61	neutral	1,06	deleterious	-5,69	high_impact	5,5	neutral	0,78	neutral	0,3	deleterious	3,86	23,5	0,05	0,35	disease	0,8	disease	0,9	disease	0,8	disease	0,69	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,1	high_impact	3,8	0,15	0,8	58,68	8,75	P	0,72	P	1	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15153	15153	G	C	MI.9195	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	407	136	G	A	gGc/gCc	7,07	1	0	probably_damaging	1	neutral	0,53	neutral	3,1	neutral	-2,58	deleterious	-4,87	high_impact	4,4	neutral	0,91	neutral	0,43	deleterious	3,05	22,4	0,06	0,35	neutral	0,49	disease	0,82	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,25	high_impact	2,8	0,33	0,8	58,68	8,75	N	0,54	P	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15153	15153	G	T	MI.9196	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	407	136	G	V	gGc/gTc	7,07	1	0	probably_damaging	1	neutral	0,58	neutral	3,05	deleterious	-3,95	deleterious	-7,31	high_impact	5,5	neutral	0,91	neutral	0,37	deleterious	3,73	23,3	0,04	0,35	disease	0,83	disease	0,92	disease	0,74	disease	0,66	3	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,3	high_impact	3,8	0,1	0,8	58,68	8,75	P	0,69	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15155	15155	C	G	MI.9197	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	409	137	Q	E	Caa/Gaa	-4,4	0	0	probably_damaging	0,99	neutral	0,27	neutral	3,01	neutral	-2,17	neutral	-2,43	high_impact	5,17	neutral	0,92	neutral	0,4	neutral	1,35	12,52	0,19	0,45	disease	0,75	disease	0,84	disease	0,81	disease	0,68	4	deleterious	0,99	neutral	0,14	deleterious	2	deleterious	0,86	low_impact	-2,59	medium_impact	-0,01	high_impact	3,5	0,28	0,8	57,89	8,75	P	0,76	P	0,93	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15155	15155	C	A	MI.9198	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	409	137	Q	K	Caa/Aaa	-4,4	0	0	probably_damaging	1	neutral	0,29	neutral	3,01	neutral	-2,57	deleterious	-3,24	high_impact	5,17	neutral	0,93	neutral	0,34	deleterious	3,74	23,3	0,15	0,4	disease	0,72	disease	0,9	disease	0,81	disease	0,72	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,01	high_impact	3,5	0,31	0,8	57,89	8,75	P	0,79	P	1	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15156	15156	A	C	MI.9199	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	410	137	Q	P	cAa/cCa	7,07	1	0	probably_damaging	1	neutral	0,21	neutral	2,93	deleterious	-4,68	deleterious	-4,87	high_impact	4,2	neutral	0,91	damaging	0,28	deleterious	3,14	22,6	0,07	0,35	disease	0,9	disease	0,91	disease	0,84	disease	0,63	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,09	high_impact	2,62	0,24	0,8	57,89	8,75	P	0,63	P	0,98	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8567	8567	T	G	MI.92	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	41	14	I	S	aTc/aGc	-4,27	0	0	possibly_damaging	0,68	neutral	0,65	neutral	4,61	neutral	-0,78	deleterious	-3,12	neutral_impact	0,17	neutral	0,84	neutral	0,5	deleterious	3,68	23,3	0,42	0,65	neutral	0,46	neutral	0,5	disease	0,62	neutral	0,49	0	neutral	0,62	deleterious	0,49	neutral	-3	deleterious	0,47	low_impact	-1,07	medium_impact	0,44	medium_impact	-0,95	0,65	0,9	13,72	12,42	N	0,22	N	0,5	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8958	8958	C	A	MI.920	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	432	144	I	M	atC/atA	7,53	1	0	probably_damaging	1	deleterious	0,01	neutral	3,92	deleterious	-4,95	deleterious	-2,76	high_impact	3,83	neutral	0,83	damaging	0,15	deleterious	3,85	23,4	0,32	0,65	disease	0,76	disease	0,59	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,77	low_impact	-3,6	medium_impact	-0,84	high_impact	2,19	0,75	0,9	49,12	8,59	N	0,51	P	0,75	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15156	15156	A	G	MI.9200	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	410	137	Q	R	cAa/cGa	7,07	1	0	probably_damaging	1	neutral	0,35	neutral	2,96	deleterious	-3,29	deleterious	-3,24	high_impact	5,51	neutral	0,93	neutral	0,37	deleterious	3,38	22,9	0,18	0,45	disease	0,76	disease	0,92	disease	0,77	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,08	high_impact	3,81	0,14	0,8	57,89	8,75	P	0,79	P	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15156	15156	A	T	MI.9201	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	410	137	Q	L	cAa/cTa	7,07	1	0	probably_damaging	1	neutral	0,66	neutral	3,11	neutral	-2,06	deleterious	-5,68	high_impact	5,17	neutral	0,93	neutral	0,36	deleterious	3,69	23,3	0,08	0,35	disease	0,86	disease	0,92	disease	0,73	disease	0,63	3	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,38	high_impact	3,5	0,22	0,8	57,89	8,75	P	0,75	P	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15157	15157	A	C	MI.9202	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	411	137	Q	H	caA/caC	8,44	1	0	probably_damaging	1	neutral	0,54	neutral	2,96	deleterious	-4,34	deleterious	-4,05	high_impact	5,51	neutral	0,92	neutral	0,3	deleterious	3,11	22,5	0,12	0,4	disease	0,9	disease	0,87	disease	0,73	disease	0,61	2	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,26	high_impact	3,81	0,33	0,8	57,89	8,75	P	0,77	P	0,97	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15157	15157	A	T	MI.9203	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	411	137	Q	H	caA/caT	8,44	1	0	probably_damaging	1	neutral	0,54	neutral	2,96	deleterious	-4,34	deleterious	-4,05	high_impact	5,51	neutral	0,92	neutral	0,3	deleterious	3,28	22,8	0,12	0,4	disease	0,9	disease	0,87	disease	0,73	disease	0,61	2	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,26	high_impact	3,81	0,33	0,8	57,89	8,75	P	0,78	P	0,97	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15158	15158	A	C	MI.9204	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	412	138	M	L	Ata/Cta	2,48	1	0	probably_damaging	0,96	neutral	0,65	neutral	3,47	neutral	0,76	neutral	-2,42	high_impact	4,63	neutral	0,94	damaging	0,08	neutral	1,24	11,97	0,26	0,45	neutral	0,34	disease	0,84	disease	0,74	disease	0,7	4	neutral	0,96	neutral	0,35	deleterious	2	deleterious	0,76	low_impact	-2,02	medium_impact	0,37	high_impact	3,01	0,19	0,8	56,84	8,61	N	0,49	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15158	15158	A	T	MI.9205	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	412	138	M	L	Ata/Tta	2,48	1	0	probably_damaging	0,96	neutral	0,65	neutral	3,47	neutral	0,76	neutral	-2,42	high_impact	4,63	neutral	0,94	damaging	0,08	neutral	1,34	12,5	0,26	0,45	neutral	0,34	disease	0,84	disease	0,74	disease	0,7	4	neutral	0,96	neutral	0,35	deleterious	2	deleterious	0,76	low_impact	-2,02	medium_impact	0,37	high_impact	3,01	0,19	0,8	56,84	8,61	N	0,49	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15158	15158	A	G	MI.9206	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	412	138	M	V	Ata/Gta	2,48	1	0	probably_damaging	0,98	neutral	0,51	neutral	3,11	neutral	-1,41	deleterious	-3,23	high_impact	4,83	neutral	0,94	damaging	0,1	deleterious	0,78	9,31	0,27	0,45	disease	0,59	disease	0,87	disease	0,77	disease	0,71	4	neutral	0,97	neutral	0,27	deleterious	2	deleterious	0,83	low_impact	-2,31	medium_impact	0,23	high_impact	3,19	0,2	0,8	56,84	8,61	P	0,71	P	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15159	15159	T	C	MI.9207	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	413	138	M	T	aTa/aCa	6,84	1	0	probably_damaging	1	neutral	0,4	neutral	3,06	neutral	-2,24	deleterious	-4,84	high_impact	5,18	neutral	0,93	damaging	0,11	deleterious	2,67	20,6	0,09	0,35	disease	0,82	disease	0,89	disease	0,76	disease	0,68	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,13	high_impact	3,51	0,12	0,8	56,84	8,61	P	0,76	P	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15159	15159	T	A	MI.9208	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	413	138	M	K	aTa/aAa	6,84	1	0	probably_damaging	0,99	neutral	0,29	neutral	3,05	neutral	-2,41	deleterious	-4,85	high_impact	5,18	neutral	0,93	damaging	0,08	deleterious	2,47	19,25	0,07	0,35	disease	0,88	disease	0,91	disease	0,82	disease	0,64	3	deleterious	0,99	neutral	0,15	deleterious	2	deleterious	0,89	low_impact	-2,59	medium_impact	0,01	high_impact	3,51	0,08	0,8	56,84	8,61	P	0,8	P	0,99	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15160	15160	A	C	MI.9209	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	414	138	M	I	atA/atC	4,54	1	0	probably_damaging	0,98	neutral	0,4	neutral	3,11	neutral	-1,31	deleterious	-3,23	high_impact	4,55	neutral	0,93	damaging	0,09	neutral	1,61	13,92	0,21	0,45	disease	0,56	disease	0,89	disease	0,73	disease	0,71	4	deleterious	0,98	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-2,31	medium_impact	0,13	high_impact	2,94	0,23	0,8	56,84	8,61	P	0,56	P	0,95	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8959	8959	G	C	MI.921	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	433	145	E	Q	Gaa/Caa	-5,66	0	0	probably_damaging	0,99	deleterious	0	neutral	3,72	deleterious	-5,44	deleterious	-2,75	high_impact	4,63	neutral	0,65	neutral	0,59	deleterious	3,33	22,9	0,37	0,65	disease	0,87	disease	0,57	disease	0,77	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,83	low_impact	-2,65	low_impact	-1,4	high_impact	2,87	0,67	0,9	49,12	8,84	P	0,56	P	0,91	disease_causing	0,91	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15160	15160	A	T	MI.9210	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	414	138	M	I	atA/atT	4,54	1	0	probably_damaging	0,98	neutral	0,4	neutral	3,11	neutral	-1,31	deleterious	-3,23	high_impact	4,55	neutral	0,93	damaging	0,09	neutral	1,69	14,35	0,21	0,45	disease	0,56	disease	0,89	disease	0,73	disease	0,71	4	deleterious	0,98	neutral	0,21	deleterious	2	deleterious	0,85	low_impact	-2,31	medium_impact	0,13	high_impact	2,94	0,23	0,8	56,84	8,61	P	0,59	P	0,95	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15161	15161	T	C	MI.9211	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	415	139	S	P	Tca/Cca	4,54	1	0	probably_damaging	1	neutral	0,21	neutral	2,66	deleterious	-6,49	deleterious	-4,05	high_impact	5	neutral	0,88	damaging	0,04	deleterious	3,81	23,4	0,06	0,35	disease	0,88	disease	0,86	disease	0,84	disease	0,65	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,09	high_impact	3,35	0,2	0,8	58,68	8,67	P	0,76	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15161	15161	T	G	MI.9212	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	415	139	S	A	Tca/Gca	4,54	1	0	probably_damaging	0,99	neutral	0,51	neutral	2,99	neutral	-1,45	neutral	-2,42	high_impact	5,2	neutral	0,88	damaging	0,14	deleterious	3,28	22,8	0,19	0,45	disease	0,61	disease	0,74	disease	0,74	disease	0,69	4	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	0,23	high_impact	3,53	0,33	0,8	58,68	8,67	P	0,71	P	0,46	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15161	15161	T	A	MI.9213	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	415	139	S	T	Tca/Aca	4,54	1	0	probably_damaging	0,99	neutral	0,4	neutral	2,69	deleterious	-4,82	neutral	-2,42	high_impact	5,54	neutral	0,86	damaging	0,1	deleterious	2,04	16,49	0,17	0,45	disease	0,75	disease	0,78	disease	0,75	disease	0,69	4	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,84	low_impact	-2,59	medium_impact	0,13	high_impact	3,84	0,44	0,8	58,68	8,67	P	0,74	P	0,7	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15162	15162	C	G	MI.9214	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	416	139	S	W	tCa/tGa	5,69	1	0	probably_damaging	1	neutral	0,19	neutral	2,64	deleterious	-9,97	deleterious	-5,66	high_impact	5,54	neutral	0,89	damaging	0,09	deleterious	4,27	23,9	0,05	0,35	disease	0,98	disease	0,91	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,12	high_impact	3,84	0,14	0,8	58,68	8,67	P	0,66	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15162	15162	C	T	MI.9215	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	416	139	S	L	tCa/tTa	5,69	1	0	probably_damaging	1	neutral	0,65	neutral	2,68	deleterious	-6,85	deleterious	-4,85	high_impact	5	neutral	0,88	damaging	0,06	deleterious	4,57	24,4	0,04	0,35	disease	0,9	disease	0,89	disease	0,73	disease	0,62	2	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,37	high_impact	3,35	0,5	0,8	58,68	8,67	P	0,77	P	1	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15164	15164	T	A	MI.9216	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	418	140	F	I	Ttc/Atc	-10,6	0	0	benign	0,36	neutral	0,4	neutral	3,14	neutral	-1,02	deleterious	-4,86	high_impact	5,11	neutral	0,94	neutral	0,48	deleterious	4,25	23,9	0,12	0,4	disease	0,81	disease	0,86	disease	0,72	disease	0,65	3	neutral	0,53	deleterious	0,52	neutral	-2	deleterious	0,62	medium_impact	-0,5	medium_impact	0,13	high_impact	3,45	0,41	0,8	55,79	8,33	P	0,64	P	0,97	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15164	15164	T	C	MI.9217	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	418	140	F	L	Ttc/Ctc	-10,6	0	0	benign	0,02	neutral	0,66	neutral	3,11	neutral	-0,48	deleterious	-4,85	medium_impact	3,42	neutral	0,94	neutral	0,61	deleterious	3,74	23,3	0,15	0,4	neutral	0,46	disease	0,81	disease	0,61	disease	0,52	0	neutral	0,3	deleterious	0,82	neutral	-3	neutral	0,24	medium_impact	0,85	medium_impact	0,38	medium_impact	1,91	0,48	0,8	55,79	8,33	N	0,29	N	0,92	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15164	15164	T	G	MI.9218	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	418	140	F	V	Ttc/Gtc	-10,6	0	0	possibly_damaging	0,68	neutral	0,51	neutral	3,17	neutral	-0,31	deleterious	-5,67	high_impact	5,11	neutral	0,94	neutral	0,5	deleterious	4,03	23,6	0,08	0,35	disease	0,8	disease	0,88	disease	0,76	disease	0,67	3	neutral	0,66	neutral	0,42	deleterious	1	deleterious	0,66	low_impact	-1,04	medium_impact	0,23	high_impact	3,45	0,32	0,8	55,79	8,33	P	0,68	P	0,99	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15165	15165	T	A	MI.9219	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	419	140	F	Y	tTc/tAc	5,69	1	0	possibly_damaging	0,72	neutral	1	neutral	3,14	neutral	0,67	neutral	-2,43	medium_impact	2,79	neutral	0,94	neutral	0,45	deleterious	4,09	23,7	0,1	0,4	neutral	0,3	disease	0,82	disease	0,69	disease	0,67	3	neutral	0,72	deleterious	0,64	NA	0	deleterious	0,67	low_impact	-1,11	high_impact	1,85	medium_impact	1,34	0,54	0,8	55,79	8,33	N	0,49	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8959	8959	G	A	MI.922	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	433	145	E	K	Gaa/Aaa	-5,66	0	0	probably_damaging	0,99	deleterious	0	neutral	3,88	deleterious	-5,32	deleterious	-3,67	high_impact	4,29	damaging	0,58	neutral	0,46	deleterious	4,53	24,3	0,33	0,65	disease	0,75	disease	0,78	disease	0,84	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,87	low_impact	-2,65	low_impact	-1,4	high_impact	2,58	0,71	0,9	49,12	8,84	N	0,46	N	1	disease_causing	0,98	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15165	15165	T	G	MI.9220	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	419	140	F	C	tTc/tGc	5,69	1	0	probably_damaging	0,99	neutral	0,18	neutral	3,03	deleterious	-3,59	deleterious	-6,49	high_impact	5,46	neutral	0,93	neutral	0,4	deleterious	4	23,6	0,04	0,35	disease	0,94	disease	0,89	disease	0,75	disease	0,62	2	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-2,59	medium_impact	-0,14	high_impact	3,76	0,26	0,8	55,79	8,33	P	0,73	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15165	15165	T	C	MI.9221	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	419	140	F	S	tTc/tCc	5,69	1	0	probably_damaging	0,99	neutral	0,42	neutral	3,07	neutral	-2,11	deleterious	-6,48	high_impact	4,76	neutral	0,93	neutral	0,44	deleterious	4,22	23,9	0,03	0,35	disease	0,86	disease	0,87	disease	0,74	disease	0,63	3	deleterious	0,99	neutral	0,22	deleterious	2	deleterious	0,85	low_impact	-2,59	medium_impact	0,15	high_impact	3,13	0,17	0,8	55,79	8,33	P	0,77	P	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15166	15166	C	A	MI.9222	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	420	140	F	L	ttC/ttA	5,69	1	0	benign	0,02	neutral	0,66	neutral	3,11	neutral	-0,48	deleterious	-4,85	medium_impact	3,42	neutral	0,94	neutral	0,61	deleterious	4,28	24	0,15	0,4	neutral	0,46	disease	0,81	disease	0,61	disease	0,52	0	neutral	0,3	deleterious	0,82	neutral	-3	neutral	0,24	medium_impact	0,85	medium_impact	0,38	medium_impact	1,91	0,48	0,8	55,79	8,33	N	0,52	P	0,92	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15166	15166	C	G	MI.9223	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	420	140	F	L	ttC/ttG	5,69	1	0	benign	0,02	neutral	0,66	neutral	3,11	neutral	-0,48	deleterious	-4,85	medium_impact	3,42	neutral	0,94	neutral	0,61	deleterious	4,04	23,7	0,15	0,4	neutral	0,46	disease	0,81	disease	0,61	disease	0,52	0	neutral	0,3	deleterious	0,82	neutral	-3	neutral	0,24	medium_impact	0,85	medium_impact	0,38	medium_impact	1,91	0,48	0,8	55,79	8,33	N	0,52	P	0,92	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15167	15167	T	G	MI.9224	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	421	141	W	G	Tga/Gga	-0,96	0,01	0	probably_damaging	1	neutral	0,48	neutral	3	deleterious	-4,13	deleterious	-10,48	high_impact	4,78	neutral	0,8	damaging	0,13	deleterious	3,73	23,3	0,03	0,35	disease	0,94	disease	0,86	disease	0,82	disease	0,63	3	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,2	high_impact	3,15	0,19	0,8	58,68	8,66	P	0,69	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15167	15167	T	C	MI.9225	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	421	141	W	R	Tga/Cga	-0,96	0,01	0	probably_damaging	1	neutral	0,35	neutral	3,01	deleterious	-3,46	deleterious	-11,29	high_impact	5,04	neutral	0,83	damaging	0,07	deleterious	3,47	23	0,02	0,35	disease	0,96	disease	0,93	disease	0,86	disease	0,65	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0,08	high_impact	3,38	0,22	0,8	58,68	8,66	P	0,66	P	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15168	15168	G	T	MI.9226	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	422	141	W	L	tGa/tTa	7,3	1	0	probably_damaging	1	neutral	0,75	neutral	3,11	neutral	-2,64	deleterious	-10,48	high_impact	5,04	neutral	0,8	damaging	0,08	deleterious	4,11	23,7	0,04	0,35	disease	0,93	disease	0,88	disease	0,8	disease	0,61	2	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,48	high_impact	3,38	0,13	0,8	58,68	8,66	P	0,7	P	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15168	15168	G	C	MI.9227	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	422	141	W	S	tGa/tCa	7,3	1	0	probably_damaging	1	neutral	0,55	neutral	3,09	neutral	-2,58	deleterious	-11,28	high_impact	4,54	neutral	0,79	damaging	0,1	deleterious	3,89	23,5	0,03	0,35	disease	0,96	disease	0,92	disease	0,81	disease	0,61	2	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,27	high_impact	2,93	0,12	0,8	58,68	8,66	P	0,55	P	0,99	disease_causing	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15169	15169	A	T	MI.9228	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	423	141	W	C	tgA/tgT	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	2,98	deleterious	-5,42	deleterious	-10,49	high_impact	4,68	neutral	0,83	damaging	0,05	deleterious	4,05	23,7	0,03	0,35	disease	0,98	disease	0,93	disease	0,85	disease	0,7	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,14	high_impact	3,06	0,19	0,8	58,68	8,66	P	0,62	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15169	15169	A	C	MI.9229	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	423	141	W	C	tgA/tgC	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	2,98	deleterious	-5,42	deleterious	-10,49	high_impact	4,68	neutral	0,83	damaging	0,05	deleterious	3,94	23,5	0,03	0,35	disease	0,98	disease	0,93	disease	0,85	disease	0,7	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,14	high_impact	3,06	0,19	0,8	58,68	8,66	P	0,61	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8960	8960	A	G	MI.923	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	434	145	E	G	gAa/gGa	3,6	1	0	probably_damaging	0,99	deleterious	0	neutral	3,69	deleterious	-6,42	deleterious	-6,43	high_impact	4,63	damaging	0,56	neutral	0,63	deleterious	4,31	24	0,3	0,65	disease	0,92	disease	0,6	disease	0,76	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,65	low_impact	-1,4	high_impact	2,87	0,4	0,9	49,12	8,84	P	0,52	P	0,71	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15170	15170	G	C	MI.9230	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	424	142	G	R	Ggg/Cgg	3,17	1	0	probably_damaging	1	neutral	0,34	neutral	2,77	deleterious	-3,59	deleterious	-6,43	high_impact	5,53	neutral	0,95	damaging	0,25	deleterious	3,92	23,5	0,02	0,35	disease	0,9	disease	0,91	disease	0,78	disease	0,65	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,07	high_impact	3,83	0,72	0,85	58,16	8,65	P	0,71	P	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15170	15170	G	T	MI.9231	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	424	142	G	W	Ggg/Tgg	3,17	1	0	probably_damaging	1	neutral	0,39	neutral	2,75	deleterious	-8,01	deleterious	-6,45	high_impact	5,17	neutral	0,89	damaging	0,24	deleterious	4,44	24,2	0,03	0,35	disease	0,98	disease	0,92	disease	0,73	disease	0,66	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,12	high_impact	3,5	0,16	0,8	58,16	8,65	P	0,64	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15171	15171	G	A	MI.9232	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	425	142	G	E	gGg/gAg	7,3	1	0	probably_damaging	1	neutral	0,29	neutral	2,79	deleterious	-4,39	deleterious	-6,43	high_impact	5,17	neutral	0,86	neutral	0,3	deleterious	3,85	23,4	0,02	0,35	disease	0,88	disease	0,9	disease	0,76	disease	0,62	2	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,01	high_impact	3,5	0,22	0,8	58,16	8,65	P	0,74	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15171	15171	G	C	MI.9233	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	425	142	G	A	gGg/gCg	7,3	1	0	probably_damaging	1	neutral	0,6	neutral	3,19	neutral	0,61	deleterious	-4,81	medium_impact	2,63	neutral	0,91	neutral	0,41	deleterious	2,99	22,2	0,05	0,35	neutral	0,44	disease	0,77	neutral	0,5	neutral	0,41	2	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,79	low_impact	-3,53	medium_impact	0,32	medium_impact	1,19	0,56	0,8	58,16	8,65	N	0,46	N	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15171	15171	G	T	MI.9234	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	425	142	G	V	gGg/gTg	7,3	1	0	probably_damaging	1	neutral	0,53	neutral	2,82	deleterious	-4,33	deleterious	-7,23	high_impact	5,53	neutral	0,91	neutral	0,35	deleterious	3,69	23,3	0,02	0,35	disease	0,76	disease	0,89	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,25	high_impact	3,83	0,17	0,8	58,16	8,65	P	0,67	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15173	15173	G	A	MI.9235	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	427	143	A	T	Gcc/Acc	-12,2	0	0	probably_damaging	1	neutral	0,75	neutral	3,07	neutral	-0,85	deleterious	-3,15	high_impact	4,54	neutral	0,92	damaging	0,12	deleterious	4,07	23,7	0,06	0,35	disease	0,68	disease	0,79	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,48	high_impact	2,93	0,64	0,8	59,21	8,78	N	0,35	N	0,79	polymorphism	1	0,04	rs878866549	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15173	15173	G	C	MI.9236	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	427	143	A	P	Gcc/Ccc	-12,2	0	0	probably_damaging	1	neutral	0,19	neutral	2,95	deleterious	-4,07	deleterious	-3,97	high_impact	4,88	neutral	0,88	damaging	0,04	deleterious	3,79	23,4	0,03	0,35	disease	0,84	disease	0,84	disease	0,77	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,12	high_impact	3,24	0,49	0,8	59,21	8,78	P	0,71	P	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15173	15173	G	T	MI.9237	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	427	143	A	S	Gcc/Tcc	-12,2	0	0	probably_damaging	1	neutral	0,77	neutral	2,98	neutral	-2,51	neutral	-2,37	high_impact	4,88	neutral	0,87	damaging	0,09	deleterious	3,58	23,2	0,09	0,35	disease	0,64	disease	0,78	disease	0,6	disease	0,66	3	deleterious	1	neutral	0,39	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,51	high_impact	3,24	0,56	0,8	59,21	8,78	P	0,58	P	0,91	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15174	15174	C	A	MI.9238	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	428	143	A	D	gCc/gAc	9,13	1	0	probably_damaging	1	neutral	0,13	neutral	2,94	deleterious	-4,41	deleterious	-4,75	high_impact	5,58	neutral	0,85	damaging	0,08	deleterious	4,39	24,1	0,02	0,35	disease	0,8	disease	0,87	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,23	high_impact	3,87	0,26	0,8	59,21	8,78	P	0,73	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15174	15174	C	T	MI.9239	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	428	143	A	V	gCc/gTc	9,13	1	0	probably_damaging	1	neutral	0,5	neutral	3,16	neutral	-0,28	deleterious	-3,17	high_impact	4,88	neutral	0,88	damaging	0,11	deleterious	4,32	24	0,05	0,35	disease	0,71	disease	0,79	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,22	high_impact	3,24	0,75	0,85	59,21	8,78	P	0,71	P	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8960	8960	A	C	MI.924	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	434	145	E	A	gAa/gCa	3,6	1	0	probably_damaging	0,99	deleterious	0	neutral	3,71	deleterious	-5,75	deleterious	-5,48	high_impact	4,63	damaging	0,58	neutral	0,56	deleterious	3,76	23,3	0,21	0,65	disease	0,88	disease	0,56	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,65	low_impact	-1,4	high_impact	2,87	0,55	0,9	49,12	8,84	P	0,52	P	0,8	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15174	15174	C	G	MI.9240	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	428	143	A	G	gCc/gGc	9,13	1	0	probably_damaging	1	neutral	0,83	neutral	2,98	neutral	-2,52	deleterious	-3,17	high_impact	4,08	neutral	0,87	damaging	0,14	deleterious	3,61	23,2	0,09	0,35	disease	0,74	disease	0,68	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,42	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	0,6	high_impact	2,51	0,69	0,85	59,21	8,78	N	0,51	P	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15176	15176	A	G	MI.9241	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	430	144	T	A	Aca/Gca	-9,22	0	0	probably_damaging	0,99	neutral	1	neutral	3,1	neutral	-1,51	deleterious	-3,92	high_impact	4,66	neutral	0,97	damaging	0,14	neutral	1,73	14,59	0,13	0,4	disease	0,6	disease	0,74	disease	0,63	disease	0,65	3	deleterious	0,99	deleterious	0,51	deleterious	2	deleterious	0,76	low_impact	-2,59	high_impact	1,85	high_impact	3,04	0,39	0,8	57,89	8,75	N	0,4	N	0,59	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15176	15176	A	T	MI.9242	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	430	144	T	S	Aca/Tca	-9,22	0	0	probably_damaging	0,99	neutral	0,59	neutral	3,1	neutral	-1,45	deleterious	-3,14	high_impact	4,06	neutral	0,93	damaging	0,1	neutral	1,73	14,59	0,25	0,45	disease	0,7	disease	0,77	disease	0,58	disease	0,64	3	deleterious	0,99	neutral	0,3	deleterious	2	deleterious	0,78	low_impact	-2,59	medium_impact	0,31	high_impact	2,49	0,56	0,8	57,89	8,75	N	0,23	N	0,81	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15176	15176	A	C	MI.9243	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	430	144	T	P	Aca/Cca	-9,22	0	0	probably_damaging	1	neutral	0,23	neutral	3,03	deleterious	-3,42	deleterious	-4,75	high_impact	4,87	neutral	0,95	damaging	0,06	deleterious	3,31	22,9	0,04	0,35	disease	0,86	disease	0,87	disease	0,76	disease	0,64	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,06	high_impact	3,23	0,35	0,8	57,89	8,75	P	0,72	P	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15177	15177	C	A	MI.9244	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	431	144	T	K	aCa/aAa	5,46	1	0	probably_damaging	1	neutral	0,26	neutral	3,12	neutral	-0,69	deleterious	-4,73	high_impact	5,56	neutral	0,94	damaging	0,08	deleterious	4,15	23,8	0,05	0,35	disease	0,78	disease	0,89	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,02	high_impact	3,86	0,41	0,8	57,89	8,75	P	0,74	P	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15177	15177	C	T	MI.9245	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	431	144	T	M	aCa/aTa	5,46	1	0	probably_damaging	1	neutral	0,24	neutral	3,04	neutral	-2,79	deleterious	-4,73	high_impact	4,06	neutral	0,94	damaging	0,1	deleterious	3,94	23,5	0,06	0,35	neutral	0,5	disease	0,85	disease	0,61	disease	0,68	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,74	low_impact	-3,53	medium_impact	-0,05	high_impact	2,49	0,49	0,8	57,89	8,75	N	0,48	N	0,96	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15179	15179	G	A	MI.9246	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	433	145	V	M	Gta/Ata	-6,24	0	0	probably_damaging	1	neutral	0,24	neutral	2,63	deleterious	-5,53	neutral	-2,37	high_impact	5,26	neutral	0,92	damaging	0,1	deleterious	3,49	23,1	0,09	0,35	disease	0,86	disease	0,82	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,05	high_impact	3,58	0,77	0,85	58,42	8,67	P	0,69	P	0,97	polymorphism	1	0,27	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	15179	15179	G	C	MI.9247	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	433	145	V	L	Gta/Cta	-6,24	0	0	probably_damaging	0,96	neutral	0,77	neutral	2,72	deleterious	-3,72	neutral	-2,37	high_impact	5,61	neutral	0,93	damaging	0,07	neutral	1,63	14,01	0,12	0,4	disease	0,7	disease	0,79	disease	0,62	disease	0,65	3	neutral	0,96	neutral	0,41	deleterious	2	deleterious	0,79	low_impact	-2,02	medium_impact	0,51	high_impact	3,9	0,5	0,8	58,42	8,67	P	0,61	P	0,69	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15179	15179	G	T	MI.9248	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	433	145	V	L	Gta/Tta	-6,24	0	0	probably_damaging	0,96	neutral	0,77	neutral	2,72	deleterious	-3,72	neutral	-2,37	high_impact	5,61	neutral	0,93	damaging	0,07	neutral	1,74	14,62	0,12	0,4	disease	0,7	disease	0,79	disease	0,62	disease	0,65	3	neutral	0,96	neutral	0,41	deleterious	2	deleterious	0,79	low_impact	-2,02	medium_impact	0,51	high_impact	3,9	0,5	0,8	58,42	8,67	P	0,61	P	0,69	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15180	15180	T	A	MI.9249	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	434	145	V	E	gTa/gAa	4,08	1	0	probably_damaging	1	neutral	0,26	neutral	2,62	deleterious	-6,96	deleterious	-4,75	high_impact	5,26	neutral	0,92	damaging	0,11	deleterious	4,37	24,1	0,02	0,35	disease	0,85	disease	0,9	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,02	high_impact	3,58	0,28	0,8	58,42	8,67	P	0,78	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8960	8960	A	T	MI.925	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	434	145	E	V	gAa/gTa	3,6	1	0	probably_damaging	1	deleterious	0	neutral	3,68	deleterious	-7,45	deleterious	-6,43	high_impact	4,63	damaging	0,5	neutral	0,49	deleterious	4,3	24	0,2	0,65	disease	0,94	disease	0,81	disease	0,78	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,88	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,58	0,9	49,12	8,84	P	0,53	P	0,86	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15180	15180	T	C	MI.9250	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	434	145	V	A	gTa/gCa	4,08	1	0	probably_damaging	1	neutral	0,61	neutral	2,71	deleterious	-4,08	deleterious	-3,15	high_impact	4,8	neutral	0,93	damaging	0,12	deleterious	3,12	22,6	0,05	0,35	disease	0,69	disease	0,7	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,33	high_impact	3,17	0,25	0,8	58,42	8,67	P	0,67	P	0,62	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15180	15180	T	G	MI.9251	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	434	145	V	G	gTa/gGa	4,08	1	0	probably_damaging	1	neutral	0,39	neutral	2,63	deleterious	-6,85	deleterious	-5,54	high_impact	5,61	neutral	0,92	damaging	0,1	deleterious	3,5	23,1	0,02	0,35	disease	0,83	disease	0,82	disease	0,68	disease	0,68	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,12	high_impact	3,9	0,3	0,8	58,42	8,67	P	0,67	P	0,96	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15182	15182	A	T	MI.9252	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	436	146	I	F	Att/Ttt	-14,27	0	0	probably_damaging	0,99	neutral	0,63	neutral	3	deleterious	-3	deleterious	-3,17	high_impact	5,6	neutral	0,95	damaging	0,1	deleterious	2,07	16,67	0,05	0,35	disease	0,84	disease	0,86	disease	0,69	disease	0,68	4	deleterious	0,99	neutral	0,32	deleterious	2	deleterious	0,84	low_impact	-2,59	medium_impact	0,35	high_impact	3,89	0,68	0,85	59,21	8,77	P	0,64	P	0,97	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15182	15182	A	C	MI.9253	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	436	146	I	L	Att/Ctt	-14,27	0	0	probably_damaging	0,95	neutral	0,7	neutral	3,09	neutral	-1,59	neutral	-1,58	high_impact	4,36	neutral	0,96	damaging	0,1	deleterious	1,86	15,33	0,18	0,45	disease	0,58	disease	0,72	disease	0,62	disease	0,66	3	neutral	0,94	neutral	0,38	deleterious	2	deleterious	0,61	low_impact	-1,92	medium_impact	0,42	high_impact	2,77	0,63	0,8	59,21	8,77	N	0,29	N	0,88	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15182	15182	A	G	MI.9254	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	436	146	I	V	Att/Gtt	-14,27	0	0	possibly_damaging	0,88	neutral	1	neutral	3,06	neutral	-1,56	neutral	-0,79	high_impact	4,36	neutral	0,95	damaging	0,13	neutral	1,11	11,26	0,49	0,55	neutral	0,41	disease	0,53	disease	0,59	disease	0,64	3	neutral	0,88	deleterious	0,56	deleterious	1	deleterious	0,53	low_impact	-1,54	high_impact	1,85	high_impact	2,77	0,68	0,85	59,21	8,77	N	0,27	N	0,83	polymorphism	1	0,05	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	15183	15183	T	G	MI.9255	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	437	146	I	S	aTt/aGt	6,84	1	0	probably_damaging	1	neutral	0,52	neutral	3	neutral	-2,84	deleterious	-4,74	high_impact	5,6	neutral	0,94	damaging	0,1	deleterious	3,91	23,5	0,02	0,35	disease	0,86	disease	0,88	disease	0,66	disease	0,67	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,24	high_impact	3,89	0,46	0,8	59,21	8,77	P	0,74	P	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15183	15183	T	A	MI.9256	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	437	146	I	N	aTt/aAt	6,84	1	0	probably_damaging	1	neutral	0,3	neutral	2,97	deleterious	-3,97	deleterious	-5,55	high_impact	5,05	neutral	0,94	damaging	0,11	deleterious	4,22	23,9	0,04	0,35	disease	0,93	disease	0,87	disease	0,69	disease	0,66	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,02	high_impact	3,39	0,63	0,8	59,21	8,77	P	0,74	P	0,99	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15183	15183	T	C	MI.9257	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	437	146	I	T	aTt/aCt	6,84	1	0	probably_damaging	1	neutral	0,62	neutral	3,07	neutral	-2,16	deleterious	-3,95	high_impact	5,25	neutral	0,94	damaging	0,1	deleterious	2,99	22,2	0,03	0,35	disease	0,62	disease	0,8	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,34	high_impact	3,57	0,35	0,8	59,21	8,77	P	0,7	P	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15184	15184	T	G	MI.9258	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	438	146	I	M	atT/atG	5,69	1	0,02	probably_damaging	1	neutral	0,23	neutral	3,02	neutral	-2,53	neutral	-2,38	high_impact	5,25	neutral	0,95	damaging	0,11	deleterious	2,98	22,2	0,07	0,35	disease	0,81	disease	0,71	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	-0,06	high_impact	3,57	0,65	0,8	59,21	8,77	P	0,71	P	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15184	15184	T	A	MI.9259	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	438	146	I	M	atT/atA	5,69	1	0,02	probably_damaging	1	neutral	0,23	neutral	3,02	neutral	-2,53	neutral	-2,38	high_impact	5,25	neutral	0,95	damaging	0,11	deleterious	3,27	22,8	0,07	0,35	disease	0,81	disease	0,71	disease	0,62	disease	0,64	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	-0,06	high_impact	3,57	0,65	0,8	59,21	8,77	P	0,73	P	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8961	8961	A	T	MI.926	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	435	145	E	D	gaA/gaT	6,84	1	0	probably_damaging	0,99	deleterious	0	neutral	3,74	deleterious	-4,91	deleterious	-2,76	high_impact	4,63	neutral	0,62	neutral	0,57	deleterious	3,81	23,4	0,38	0,65	disease	0,82	disease	0,58	disease	0,77	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,65	low_impact	-1,4	high_impact	2,87	0,63	0,9	49,12	8,84	P	0,66	P	0,87	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15185	15185	A	T	MI.9260	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	439	147	T	S	Aca/Tca	-4,63	0	0	possibly_damaging	0,49	neutral	0,48	neutral	3,13	neutral	-1,88	deleterious	-3,15	high_impact	4,41	neutral	0,86	damaging	0,09	deleterious	2,87	21,7	0,28	0,45	disease	0,66	disease	0,78	disease	0,65	disease	0,66	3	neutral	0,51	deleterious	0,5	deleterious	1	deleterious	0,51	medium_impact	-0,72	medium_impact	0,2	high_impact	2,81	0,74	0,85	58,16	8,74	N	0,35	N	0,81	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15185	15185	A	C	MI.9261	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	439	147	T	P	Aca/Cca	-4,63	0	0	probably_damaging	0,94	neutral	0,32	neutral	3,02	deleterious	-3,55	deleterious	-4,76	high_impact	5,26	neutral	0,88	damaging	0,06	deleterious	3,37	22,9	0,04	0,35	disease	0,87	disease	0,86	disease	0,78	disease	0,65	3	neutral	0,95	neutral	0,19	deleterious	2	deleterious	0,84	low_impact	-1,85	medium_impact	0,05	high_impact	3,58	0,5	0,8	58,16	8,74	P	0,72	P	0,95	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15185	15185	A	G	MI.9262	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	439	147	T	A	Aca/Gca	-4,63	0	0	benign	0,34	neutral	0,63	neutral	3,24	neutral	-1,69	deleterious	-3,94	high_impact	4,92	neutral	0,87	damaging	0,12	deleterious	3	22,2	0,14	0,4	neutral	0,47	disease	0,71	disease	0,63	disease	0,64	3	neutral	0,3	deleterious	0,65	neutral	-2	neutral	0,37	medium_impact	-0,46	medium_impact	0,35	high_impact	3,27	0,31	0,8	58,16	8,74	N	0,52	P	0,59	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15186	15186	C	A	MI.9263	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	440	147	T	K	aCa/aAa	5,46	1	0	possibly_damaging	0,66	neutral	0,25	neutral	3,1	neutral	-2,98	deleterious	-4,75	high_impact	5,05	neutral	0,86	damaging	0,07	deleterious	4,18	23,8	0,05	0,35	disease	0,89	disease	0,89	disease	0,76	disease	0,62	2	neutral	0,78	neutral	0,3	deleterious	1	deleterious	0,77	medium_impact	-1	medium_impact	-0,04	high_impact	3,39	0,51	0,8	58,16	8,74	P	0,74	P	0,97	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15186	15186	C	T	MI.9264	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	440	147	T	M	aCa/aTa	5,46	1	0	possibly_damaging	0,44	neutral	0,22	neutral	3,03	deleterious	-3,32	deleterious	-4,74	high_impact	5,61	neutral	0,86	damaging	0,13	deleterious	3,91	23,5	0,06	0,35	disease	0,93	disease	0,85	disease	0,69	disease	0,6	2	neutral	0,75	neutral	0,39	deleterious	1	deleterious	0,5	medium_impact	-0,63	medium_impact	-0,08	high_impact	3,9	0,58	0,8	58,16	8,74	P	0,68	P	0,96	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15188	15188	A	G	MI.9265	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	442	148	N	D	Aac/Gac	-20	0	0	probably_damaging	0,99	neutral	0,19	neutral	3,03	neutral	-2,45	deleterious	-3,96	high_impact	5,55	neutral	0,79	neutral	0,34	deleterious	3,39	23	0,26	0,45	disease	0,52	disease	0,82	disease	0,76	disease	0,7	4	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,8	low_impact	-2,59	medium_impact	-0,12	high_impact	3,85	0,37	0,8	58,68	8,71	P	0,68	P	0,96	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15188	15188	A	C	MI.9266	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	442	148	N	H	Aac/Cac	-20	0	0	probably_damaging	1	neutral	0,51	neutral	3	deleterious	-4,06	deleterious	-3,96	high_impact	5,21	neutral	0,82	damaging	0,19	deleterious	2,94	22	0,13	0,4	disease	0,81	disease	0,85	disease	0,75	disease	0,67	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,23	high_impact	3,54	0,31	0,8	58,68	8,71	P	0,7	P	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15188	15188	A	T	MI.9267	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	442	148	N	Y	Aac/Tac	-20	0	0	probably_damaging	1	neutral	1	neutral	2,99	deleterious	-4,8	deleterious	-6,33	high_impact	4,86	neutral	0,83	neutral	0,32	deleterious	3,59	23,2	0,05	0,35	disease	0,89	disease	0,91	disease	0,7	disease	0,62	2	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,88	low_impact	-3,53	high_impact	1,85	high_impact	3,22	0,23	0,8	58,68	8,71	P	0,58	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15189	15189	A	G	MI.9268	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	443	148	N	S	aAc/aGc	8,44	1	0	probably_damaging	0,98	neutral	0,51	neutral	3,18	neutral	-1,75	deleterious	-3,94	medium_impact	3,09	neutral	0,83	neutral	0,39	neutral	1,15	11,46	0,29	0,45	neutral	0,28	disease	0,84	disease	0,53	disease	0,66	3	neutral	0,97	neutral	0,27	deleterious	1	deleterious	0,77	low_impact	-2,31	medium_impact	0,23	medium_impact	1,61	0,36	0,8	58,68	8,71	N	0,5	N	0,91	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15189	15189	A	C	MI.9269	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	443	148	N	T	aAc/aCc	8,44	1	0	probably_damaging	1	neutral	0,91	neutral	3,04	deleterious	-3,22	deleterious	-4,73	high_impact	4,66	neutral	0,86	neutral	0,42	deleterious	2,9	21,9	0,12	0,4	disease	0,71	disease	0,85	disease	0,63	disease	0,67	3	deleterious	0,99	neutral	0,46	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,77	high_impact	3,04	0,33	0,8	58,68	8,71	P	0,58	P	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8961	8961	A	C	MI.927	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	435	145	E	D	gaA/gaC	6,84	1	0	probably_damaging	0,99	deleterious	0	neutral	3,74	deleterious	-4,91	deleterious	-2,76	high_impact	4,63	neutral	0,62	neutral	0,57	deleterious	3,71	23,3	0,38	0,65	disease	0,82	disease	0,58	disease	0,77	disease	0,75	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,65	low_impact	-1,4	high_impact	2,87	0,63	0,9	49,12	8,84	P	0,66	P	0,87	disease_causing	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15189	15189	A	T	MI.9270	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	443	148	N	I	aAc/aTc	8,44	1	0	probably_damaging	1	neutral	0,63	neutral	3	deleterious	-5,78	deleterious	-7,12	high_impact	5	neutral	0,84	neutral	0,41	deleterious	3,62	23,2	0,06	0,35	disease	0,87	disease	0,93	disease	0,67	disease	0,63	3	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,35	high_impact	3,35	0,23	0,8	58,68	8,71	P	0,69	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15190	15190	C	A	MI.9271	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	444	148	N	K	aaC/aaA	5,46	1	0	probably_damaging	1	neutral	0,28	neutral	3,1	neutral	-2,66	deleterious	-4,75	high_impact	4,75	neutral	0,83	damaging	0,27	deleterious	4,23	23,9	0,15	0,4	disease	0,63	disease	0,88	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0	high_impact	3,12	0,48	0,8	58,68	8,71	P	0,75	P	1	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15190	15190	C	G	MI.9272	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	444	148	N	K	aaC/aaG	5,46	1	0	probably_damaging	1	neutral	0,28	neutral	3,1	neutral	-2,66	deleterious	-4,75	high_impact	4,75	neutral	0,83	damaging	0,27	deleterious	3,81	23,4	0,15	0,4	disease	0,63	disease	0,88	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0	high_impact	3,12	0,48	0,8	58,68	8,71	P	0,74	P	1	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15191	15191	T	G	MI.9273	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	445	149	L	V	Tta/Gta	-1,88	0	0,01	probably_damaging	0,99	neutral	0,56	neutral	2,92	neutral	-1,44	neutral	-2,33	high_impact	4,54	neutral	0,84	neutral	0,47	deleterious	2,99	22,2	0,23	0,45	NA	NA	disease	0,69	disease	0,63	disease	0,65	3	deleterious	0,99	neutral	0,29	deleterious	2	deleterious	0,83	low_impact	-2,59	medium_impact	0,28	high_impact	2,93	0,47	0,8	58,16	8,78	N	0,38	N	0,91	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15191	15191	T	A	MI.9274	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	445	149	L	M	Tta/Ata	-1,88	0	0,01	probably_damaging	1	neutral	0,22	neutral	2,81	deleterious	-3,18	neutral	-1,43	high_impact	3,6	neutral	0,76	neutral	0,44	deleterious	3,69	23,3	0,21	0,45	NA	NA	disease	0,61	disease	0,55	neutral	0,48	0	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	-0,08	high_impact	2,08	0,46	0,8	58,16	8,78	N	0,4	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15192	15192	T	G	MI.9275	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	446	149	L	W	tTa/tGa	0,18	0,02	0	probably_damaging	1	neutral	0,19	neutral	2,79	deleterious	-3,78	deleterious	-4,7	high_impact	5,58	neutral	0,84	neutral	0,35	deleterious	3,73	23,3	0,04	0,35	NA	NA	disease	0,79	disease	0,67	disease	0,65	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,12	high_impact	3,87	0,24	0,8	58,16	8,78	P	0,64	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15192	15192	T	C	MI.9276	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	446	149	L	S	tTa/tCa	0,18	0,02	0	probably_damaging	1	neutral	0,43	neutral	2,8	deleterious	-3,36	deleterious	-4,68	high_impact	4,67	neutral	0,83	neutral	0,45	deleterious	3,64	23,2	0,02	0,35	NA	NA	disease	0,82	disease	0,64	disease	0,65	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,16	high_impact	3,05	0,42	0,8	58,16	8,78	N	0,53	P	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15193	15193	A	T	MI.9277	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	447	149	L	F	ttA/ttT	5,69	0,87	0	probably_damaging	1	neutral	0,7	neutral	2,85	neutral	-2,26	deleterious	-3,13	high_impact	3,58	neutral	0,91	neutral	0,45	deleterious	3,45	23	0,13	0,4	NA	NA	disease	0,8	disease	0,58	disease	0,64	3	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,42	high_impact	2,06	0,51	0,8	58,16	8,78	N	0,41	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15193	15193	A	C	MI.9278	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	447	149	L	F	ttA/ttC	5,69	0,87	0	probably_damaging	1	neutral	0,7	neutral	2,85	neutral	-2,26	deleterious	-3,13	high_impact	3,58	neutral	0,91	neutral	0,45	deleterious	3,32	22,9	0,13	0,4	NA	NA	disease	0,8	disease	0,58	disease	0,64	3	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,42	high_impact	2,06	0,51	0,8	58,16	8,78	N	0,41	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15194	15194	C	G	MI.9279	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	448	150	L	V	Cta/Gta	-10,83	0	0	probably_damaging	0,98	neutral	0,46	neutral	3,07	neutral	-0,66	neutral	-2,1	medium_impact	3,01	neutral	0,95	damaging	0,1	neutral	1,67	14,23	0,24	0,45	NA	NA	disease	0,62	neutral	0,35	neutral	0,36	3	neutral	0,98	neutral	0,24	deleterious	1	deleterious	0,79	low_impact	-2,31	medium_impact	0,18	medium_impact	1,54	0,46	0,8	51,58	8,37	N	0,26	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8962	8962	A	G	MI.928	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	436	146	T	A	Acc/Gcc	0,59	0,99	0,01	probably_damaging	0,99	neutral	0,05	neutral	4,26	neutral	-0,37	deleterious	-4,58	high_impact	3,55	neutral	0,69	neutral	0,52	deleterious	3,4	23	0,49	0,65	neutral	0,46	disease	0,57	disease	0,6	disease	0,63	3	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,71	low_impact	-2,65	medium_impact	-0,43	medium_impact	1,95	0,46	0,9	50	8,58	P	0,49	N	0,63	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15194	15194	C	A	MI.9280	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	448	150	L	M	Cta/Ata	-10,83	0	0	probably_damaging	1	neutral	0,18	neutral	3,01	neutral	-1,18	neutral	-1,27	medium_impact	2,64	neutral	0,97	neutral	0,29	deleterious	3,5	23,1	0,23	0,45	NA	NA	disease	0,52	neutral	0,35	neutral	0,19	6	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,76	low_impact	-3,53	medium_impact	-0,14	medium_impact	1,2	0,52	0,8	51,58	8,37	N	0,4	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15195	15195	T	A	MI.9281	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	449	150	L	Q	cTa/cAa	-1,88	0	0	probably_damaging	1	neutral	0,2	neutral	2,88	deleterious	-4	deleterious	-4,27	high_impact	4,79	neutral	0,94	damaging	0,07	deleterious	4,12	23,8	0,02	0,35	NA	NA	disease	0,8	disease	0,56	disease	0,63	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,1	high_impact	3,16	0,23	0,8	51,58	8,37	P	0,61	P	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15195	15195	T	C	MI.9282	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	449	150	L	P	cTa/cCa	-1,88	0	0	probably_damaging	1	neutral	0,21	neutral	2,87	deleterious	-4,39	deleterious	-5,09	high_impact	4,99	neutral	0,94	damaging	0,06	deleterious	3,87	23,5	0,01	0,35	NA	NA	disease	0,84	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,09	high_impact	3,34	0,22	0,8	51,58	8,37	P	0,62	P	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15195	15195	T	G	MI.9283	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	449	150	L	R	cTa/cGa	-1,88	0	0	probably_damaging	1	neutral	0,24	neutral	2,88	deleterious	-3,82	deleterious	-4,31	high_impact	5,34	neutral	0,94	damaging	0,06	deleterious	4,02	23,6	0,01	0,35	NA	NA	disease	0,89	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,05	high_impact	3,66	0,15	0,8	51,58	8,37	P	0,68	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15197	15197	T	C	MI.9284	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	451	151	S	P	Tcc/Ccc	-7,38	0	0	probably_damaging	1	neutral	0,26	neutral	2,92	deleterious	-3,64	deleterious	-4,03	high_impact	4,86	neutral	0,9	damaging	0,06	deleterious	3,51	23,1	0,05	0,35	NA	NA	disease	0,85	disease	0,8	disease	0,7	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,02	high_impact	3,22	0,15	0,8	58,16	8,74	P	0,72	P	1	disease_causing_automatic	0	0,18	rs207460001	Pathogenic	Exercise_intolerance	RCV000010320.4	MedGen	.	.	.	.	T15197C	EXIT	-	+	Reported	2
chrM	15197	15197	T	G	MI.9285	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	451	151	S	A	Tcc/Gcc	-7,38	0	0	probably_damaging	0,98	neutral	0,59	neutral	2,97	neutral	-1,9	neutral	-2,4	high_impact	5,2	neutral	0,89	damaging	0,12	deleterious	1,85	15,26	0,18	0,45	NA	NA	disease	0,62	disease	0,68	disease	0,65	3	neutral	0,98	neutral	0,31	deleterious	2	deleterious	0,77	low_impact	-2,31	medium_impact	0,31	high_impact	3,53	0,38	0,8	58,16	8,74	N	0,58	P	0,46	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15197	15197	T	A	MI.9286	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	451	151	S	T	Tcc/Acc	-7,38	0	0	probably_damaging	0,96	neutral	0,5	neutral	2,99	neutral	-1,65	neutral	-2,4	medium_impact	3,17	neutral	0,88	damaging	0,08	deleterious	1,87	15,38	0,21	0,45	NA	NA	disease	0,72	disease	0,64	disease	0,64	3	neutral	0,96	neutral	0,27	deleterious	1	deleterious	0,81	low_impact	-2,02	medium_impact	0,22	medium_impact	1,69	0,53	0,8	58,16	8,74	N	0,23	N	0,7	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15198	15198	C	A	MI.9287	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	452	151	S	Y	tCc/tAc	4,54	1	0	probably_damaging	1	neutral	1	neutral	2,92	deleterious	-3,67	deleterious	-4,82	high_impact	4,22	neutral	0,91	damaging	0,06	deleterious	4	23,6	0,05	0,35	NA	NA	disease	0,87	disease	0,71	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,87	low_impact	-3,53	high_impact	1,85	high_impact	2,64	0,13	0,8	58,16	8,74	N	0,41	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15198	15198	C	G	MI.9288	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	452	151	S	C	tCc/tGc	4,54	1	0	probably_damaging	1	neutral	0,17	neutral	2,9	deleterious	-5,52	deleterious	-4,03	high_impact	5,2	neutral	0,87	damaging	0,05	deleterious	3,38	22,9	0,07	0,35	NA	NA	disease	0,82	disease	0,68	disease	0,66	3	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,15	high_impact	3,53	0,24	0,8	58,16	8,74	P	0,65	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15198	15198	C	T	MI.9289	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	452	151	S	F	tCc/tTc	4,54	1	0	probably_damaging	1	neutral	0,73	neutral	2,91	deleterious	-4,57	deleterious	-4,81	high_impact	5	neutral	0,91	damaging	0,07	deleterious	4	23,6	0,05	0,35	NA	NA	disease	0,9	disease	0,72	disease	0,69	4	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,46	high_impact	3,35	0,06	0,8	58,16	8,74	P	0,69	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8962	8962	A	C	MI.929	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	436	146	T	P	Acc/Ccc	0,59	0,99	0,01	probably_damaging	1	deleterious	0	neutral	4,19	neutral	-2,95	deleterious	-5,57	high_impact	4,24	damaging	0,57	neutral	0,41	deleterious	3,44	23	0,17	0,65	disease	0,86	disease	0,81	disease	0,74	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,6	low_impact	-1,4	high_impact	2,54	0,64	0,9	50	8,58	N	0,42	N	0,99	disease_causing	1	0,29	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15200	15200	G	A	MI.9290	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	454	152	A	T	Gcc/Acc	-1,88	0	0	probably_damaging	1	neutral	0,4	neutral	3,07	neutral	-2,23	deleterious	-3,2	medium_impact	2,8	neutral	0,94	damaging	0,11	deleterious	3,9	23,5	0,12	0,4	disease	0,63	disease	0,85	neutral	0,48	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,85	low_impact	-3,53	medium_impact	0,13	medium_impact	1,35	0,76	0,85	58,16	8,78	N	0,3	N	0,79	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15200	15200	G	C	MI.9291	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	454	152	A	P	Gcc/Ccc	-1,88	0	0	probably_damaging	1	neutral	0,21	neutral	2,99	deleterious	-4,12	deleterious	-4,05	high_impact	4,66	neutral	0,95	damaging	0,04	deleterious	3,71	23,3	0,04	0,35	disease	0,81	disease	0,89	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,09	high_impact	3,04	0,5	0,8	58,16	8,78	P	0,64	P	0,98	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15200	15200	G	T	MI.9292	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	454	152	A	S	Gcc/Tcc	-1,88	0	0	probably_damaging	1	neutral	0,43	neutral	3,22	neutral	-0,55	neutral	-2,41	high_impact	3,65	neutral	0,94	damaging	0,09	deleterious	3,33	22,9	0,16	0,45	disease	0,58	disease	0,87	disease	0,57	disease	0,69	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,16	high_impact	2,12	0,38	0,8	58,16	8,78	N	0,31	N	0,91	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15201	15201	C	A	MI.9293	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	455	152	A	D	gCc/gAc	5,92	1	0	probably_damaging	1	neutral	0,21	neutral	3,01	neutral	-2,86	deleterious	-4,84	high_impact	5,12	neutral	0,93	damaging	0,08	deleterious	4,37	24,1	0,03	0,35	disease	0,75	disease	0,93	disease	0,76	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,09	high_impact	3,46	0,29	0,8	58,16	8,78	P	0,74	P	1	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15201	15201	C	T	MI.9294	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	455	152	A	V	gCc/gTc	5,92	1	0	probably_damaging	1	neutral	0,51	neutral	3,06	neutral	-2,67	deleterious	-3,23	medium_impact	3,06	neutral	0,95	damaging	0,11	deleterious	4,14	23,8	0,1	0,4	neutral	0,47	disease	0,88	disease	0,6	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,83	low_impact	-3,53	medium_impact	0,23	medium_impact	1,59	0,74	0,85	58,16	8,78	N	0,5	N	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15201	15201	C	G	MI.9295	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	455	152	A	G	gCc/gGc	5,92	1	0	probably_damaging	0,99	neutral	0,33	neutral	3,1	neutral	-1,43	deleterious	-3,23	high_impact	4,78	neutral	0,94	damaging	0,14	deleterious	2,26	17,92	0,18	0,45	disease	0,54	disease	0,83	disease	0,66	disease	0,69	4	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	0,06	high_impact	3,15	0,65	0,8	58,16	8,78	P	0,71	P	0,83	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15203	15203	A	T	MI.9296	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	457	153	I	F	Atc/Ttc	-8,99	0	0	benign	0,33	neutral	0,68	neutral	2,98	deleterious	-3,22	deleterious	-2,7	medium_impact	2,77	neutral	0,95	neutral	0,36	deleterious	2,08	16,71	0,14	0,4	disease	0,82	disease	0,83	neutral	0,48	disease	0,54	1	neutral	0,26	deleterious	0,68	neutral	-3	deleterious	0,59	medium_impact	-0,44	medium_impact	0,4	medium_impact	1,32	0,51	0,8	20	15,17	N	0,2	N	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15203	15203	A	C	MI.9297	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	457	153	I	L	Atc/Ctc	-8,99	0	0	benign	0,03	neutral	0,69	neutral	3,05	neutral	-1,81	neutral	-1,37	medium_impact	2,9	neutral	0,97	neutral	0,36	deleterious	1,86	15,31	0,27	0,45	neutral	0,49	disease	0,74	neutral	0,43	neutral	0,48	0	neutral	0,26	deleterious	0,83	neutral	-3	neutral	0,24	medium_impact	0,68	medium_impact	0,41	medium_impact	1,44	0,52	0,8	20	15,17	N	0,21	N	0,88	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15203	15203	A	G	MI.9298	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	457	153	I	V	Atc/Gtc	-8,99	0	0	benign	0	neutral	0,57	neutral	3,08	neutral	-1,39	neutral	-0,22	low_impact	0,94	neutral	0,99	neutral	0,69	neutral	-0,33	0,58	0,46	0,55	neutral	0,34	neutral	0,13	neutral	0,41	neutral	0,28	5	neutral	0,43	deleterious	0,79	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	0,29	medium_impact	-0,34	0,54	0,8	20	15,17	N	0,34	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15204	15204	T	C	MI.9299	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	458	153	I	T	aTc/aCc	1,56	0,84	0,01	benign	0,31	neutral	0,45	neutral	2,95	neutral	-2,19	deleterious	-3,1	medium_impact	2,35	neutral	0,98	neutral	0,54	neutral	1,64	14,07	0,07	0,35	disease	0,54	disease	0,75	disease	0,57	disease	0,51	0	neutral	0,46	deleterious	0,57	neutral	-3	neutral	0,37	medium_impact	-0,41	medium_impact	0,18	medium_impact	0,94	0,28	0,8	20	15,17	N	0,3	N	0,99	polymorphism	1	0,04	rs28357687	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8568	8568	C	G	MI.93	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	42	14	I	M	atC/atG	1,75	0,01	0	possibly_damaging	0,82	neutral	0,26	neutral	4,59	neutral	-1,38	neutral	-0,03	neutral_impact	0,62	neutral	0,91	neutral	0,9	deleterious	3,74	23,3	0,62	0,7	neutral	0,37	neutral	0,21	neutral	0,32	neutral	0,36	3	neutral	0,87	neutral	0,22	neutral	-3	deleterious	0,53	low_impact	-1,38	medium_impact	0,04	medium_impact	-0,57	0,83	0,9	13,72	12,42	P	0,54	P	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8962	8962	A	T	MI.930	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	436	146	T	S	Acc/Tcc	0,59	0,99	0,01	probably_damaging	0,99	neutral	0,14	neutral	4,22	neutral	-1,13	deleterious	-3,66	medium_impact	2,23	neutral	0,75	neutral	0,54	deleterious	3,14	22,6	0,5	0,65	disease	0,64	disease	0,55	neutral	0,46	neutral	0,45	1	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,74	low_impact	-2,65	medium_impact	-0,15	medium_impact	0,81	0,77	0,9	50	8,58	N	0,45	N	0,88	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15204	15204	T	A	MI.9300	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	458	153	I	N	aTc/aAc	1,56	0,84	0,01	possibly_damaging	0,87	neutral	0,33	neutral	2,85	deleterious	-5,13	deleterious	-4,97	high_impact	4,73	neutral	0,93	neutral	0,36	deleterious	4,02	23,6	0,14	0,4	disease	0,93	disease	0,89	disease	0,66	disease	0,76	5	neutral	0,88	neutral	0,23	deleterious	1	deleterious	0,83	low_impact	-1,5	medium_impact	0,06	high_impact	3,1	0,36	0,8	20	15,17	P	0,63	P	0,99	polymorphism	1	0,19	rs28357687	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15204	15204	T	G	MI.9301	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	458	153	I	S	aTc/aGc	1,56	0,84	0,01	possibly_damaging	0,6	neutral	0,44	neutral	2,87	deleterious	-3,8	deleterious	-4,1	high_impact	5,08	neutral	0,94	neutral	0,37	deleterious	2,66	20,5	0,05	0,35	disease	0,86	disease	0,89	disease	0,63	disease	0,75	5	neutral	0,61	neutral	0,42	deleterious	1	deleterious	0,61	medium_impact	-0,9	medium_impact	0,17	high_impact	3,42	0,24	0,8	20	15,17	P	0,62	P	0,98	polymorphism	1	0,09	rs28357687	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15205	15205	C	A	MI.9302	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	459	153	I	M	atC/atA	5,69	0,98	0	possibly_damaging	0,6	neutral	0,21	neutral	2,88	neutral	-2,83	neutral	-1,86	medium_impact	2,87	neutral	0,93	neutral	0,39	deleterious	2,14	17,11	0,25	0,45	disease	0,79	disease	0,68	disease	0,57	disease	0,62	2	neutral	0,79	neutral	0,31	NA	0	deleterious	0,48	medium_impact	-0,9	medium_impact	-0,09	medium_impact	1,41	0,51	0,8	20	15,17	N	0,56	P	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15205	15205	C	G	MI.9303	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	459	153	I	M	atC/atG	5,69	0,98	0	possibly_damaging	0,6	neutral	0,21	neutral	2,88	neutral	-2,83	neutral	-1,86	medium_impact	2,87	neutral	0,93	neutral	0,39	neutral	1,7	14,39	0,25	0,45	disease	0,79	disease	0,68	disease	0,57	disease	0,62	2	neutral	0,79	neutral	0,31	NA	0	deleterious	0,48	medium_impact	-0,9	medium_impact	-0,09	medium_impact	1,41	0,51	0,8	20	15,17	N	0,56	P	0,83	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15206	15206	C	A	MI.9304	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	460	154	P	T	Cca/Aca	-1,88	0	0	probably_damaging	1	neutral	0,39	neutral	2,16	deleterious	-7,47	deleterious	-6,44	high_impact	5,29	neutral	0,92	damaging	0,11	deleterious	3,24	22,8	0,1	0,4	disease	0,79	disease	0,86	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,12	high_impact	3,61	0,49	0,8	60,26	8,68	P	0,66	P	0,96	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15206	15206	C	G	MI.9305	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	460	154	P	A	Cca/Gca	-1,88	0	0	probably_damaging	0,98	neutral	0,51	neutral	2,18	deleterious	-6,45	deleterious	-6,44	high_impact	5,64	neutral	0,94	damaging	0,15	neutral	1,24	11,97	0,11	0,4	disease	0,71	disease	0,77	disease	0,72	disease	0,69	4	neutral	0,97	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-2,31	medium_impact	0,23	high_impact	3,93	0,65	0,8	60,26	8,68	P	0,6	P	0,84	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15206	15206	C	T	MI.9306	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	460	154	P	S	Cca/Tca	-1,88	0	0	probably_damaging	1	neutral	0,4	neutral	2,17	deleterious	-6,22	deleterious	-6,44	high_impact	5,64	neutral	0,93	damaging	0,1	deleterious	3,46	23	0,08	0,35	disease	0,75	disease	0,87	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,13	high_impact	3,93	0,15	0,8	60,26	8,68	P	0,67	P	0,9	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15207	15207	C	G	MI.9307	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	461	154	P	R	cCa/cGa	5,46	0,99	0	probably_damaging	1	neutral	0,34	neutral	2,15	deleterious	-7,82	deleterious	-7,26	high_impact	5,64	neutral	0,93	damaging	0,08	deleterious	3,46	23	0,04	0,35	disease	0,87	disease	0,92	disease	0,81	disease	0,7	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0,07	high_impact	3,93	0,31	0,8	60,26	8,68	P	0,69	P	0,8	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15207	15207	C	A	MI.9308	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	461	154	P	Q	cCa/cAa	5,46	0,99	0	probably_damaging	1	neutral	0,29	neutral	2,15	deleterious	-8	deleterious	-6,46	high_impact	5,64	neutral	0,93	damaging	0,09	deleterious	3,96	23,6	0,08	0,35	disease	0,89	disease	0,89	disease	0,75	disease	0,67	3	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,01	high_impact	3,93	0,28	0,8	60,26	8,68	P	0,71	P	0,86	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15207	15207	C	T	MI.9309	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	461	154	P	L	cCa/cTa	5,46	0,99	0	probably_damaging	1	neutral	0,65	neutral	2,15	deleterious	-7,41	deleterious	-8,07	high_impact	4,95	neutral	0,94	damaging	0,07	deleterious	4,21	23,9	0,04	0,35	disease	0,72	disease	0,92	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,37	high_impact	3,3	0,67	0,85	60,26	8,68	P	0,63	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8963	8963	C	A	MI.931	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	437	146	T	N	aCc/aAc	8,69	1	0	probably_damaging	1	deleterious	0	neutral	4,19	neutral	-2,63	deleterious	-4,62	high_impact	4,24	neutral	0,66	neutral	0,46	deleterious	3,82	23,4	0,4	0,65	disease	0,83	disease	0,72	disease	0,58	disease	0,69	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,76	low_impact	-3,6	low_impact	-1,4	high_impact	2,54	0,82	0,9	50	8,58	P	0,51	P	0,9	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15209	15209	T	A	MI.9310	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	463	155	Y	N	Tac/Aac	-14,72	0	0,01	probably_damaging	1	neutral	0,3	neutral	3,06	neutral	-1,49	deleterious	-7,25	high_impact	4,89	neutral	0,83	neutral	0,46	deleterious	3,65	23,2	0,08	0,35	disease	0,69	disease	0,89	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,02	high_impact	3,25	0,1	0,8	58,42	8,68	P	0,62	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15209	15209	T	G	MI.9311	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	463	155	Y	D	Tac/Gac	-14,72	0	0,01	probably_damaging	1	neutral	0,2	neutral	3,05	neutral	-2,68	deleterious	-8,05	high_impact	5,45	neutral	0,79	neutral	0,38	deleterious	3,61	23,2	0,04	0,35	disease	0,79	disease	0,9	disease	0,79	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,1	high_impact	3,76	0,1	0,8	58,42	8,68	P	0,69	P	1	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15209	15209	T	C	MI.9312	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	463	155	Y	H	Tac/Cac	-14,72	0	0,01	probably_damaging	1	neutral	0,54	neutral	3,05	neutral	-2,03	deleterious	-4,03	high_impact	4,64	neutral	0,82	neutral	0,38	deleterious	3,12	22,6	0,12	0,4	disease	0,7	disease	0,87	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,26	high_impact	3,02	0,13	0,8	58,42	8,68	P	0,62	P	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	T15209C	Prader-Willi syndrome	+	-	Reported	1
chrM	15210	15210	A	T	MI.9313	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	464	155	Y	F	tAc/tTc	7,3	1	0	probably_damaging	0,97	neutral	0,7	neutral	3,17	neutral	1,51	deleterious	-3,21	medium_impact	2,8	neutral	0,87	neutral	0,68	neutral	1,39	12,72	0,26	0,45	neutral	0,27	disease	0,87	disease	0,64	disease	0,69	4	neutral	0,97	neutral	0,37	deleterious	1	deleterious	0,77	low_impact	-2,14	medium_impact	0,42	medium_impact	1,35	0,32	0,8	58,42	8,68	N	0,5	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15210	15210	A	C	MI.9314	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	464	155	Y	S	tAc/tCc	7,3	1	0	probably_damaging	1	neutral	0,4	neutral	3,08	neutral	-0,42	deleterious	-7,23	high_impact	4,89	neutral	0,83	neutral	0,49	deleterious	3,21	22,7	0,07	0,35	disease	0,53	disease	0,89	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,13	high_impact	3,25	0,12	0,8	58,42	8,68	P	0,68	P	1	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15210	15210	A	G	MI.9315	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	464	155	Y	C	tAc/tGc	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	3,06	neutral	-1,85	deleterious	-7,26	high_impact	4,64	neutral	0,84	neutral	0,34	deleterious	3,27	22,8	0,06	0,35	disease	0,72	disease	0,9	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,14	high_impact	3,02	0,12	0,8	58,42	8,68	P	0,62	P	1	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15212	15212	A	C	MI.9316	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	466	156	I	L	Att/Ctt	-2,11	0	0	possibly_damaging	0,84	neutral	0,63	neutral	3,15	neutral	-1,32	neutral	-0,94	low_impact	1,38	neutral	0,95	neutral	0,4	neutral	1,65	14,14	0,29	0,45	neutral	0,27	disease	0,64	neutral	0,35	neutral	0,35	3	neutral	0,81	neutral	0,4	neutral	-3	neutral	0,37	low_impact	-1,4	medium_impact	0,35	medium_impact	0,06	0,67	0,85	45,53	8,75	N	0,25	N	0,88	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15212	15212	A	T	MI.9317	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	466	156	I	F	Att/Ttt	-2,11	0	0	probably_damaging	0,97	neutral	0,67	neutral	2,99	deleterious	-3,08	deleterious	-2,67	medium_impact	3,1	neutral	0,95	neutral	0,42	neutral	1,67	14,26	0,14	0,4	disease	0,6	disease	0,82	disease	0,56	disease	0,64	3	neutral	0,97	neutral	0,35	deleterious	1	deleterious	0,77	low_impact	-2,14	medium_impact	0,39	medium_impact	1,62	0,6	0,8	45,53	8,75	N	0,2	N	0,97	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15212	15212	A	G	MI.9318	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	466	156	I	V	Att/Gtt	-2,11	0	0	possibly_damaging	0,66	neutral	0,52	neutral	3,11	neutral	-0,55	neutral	-0,32	low_impact	0,8	neutral	0,98	neutral	0,87	neutral	-0,46	0,28	0,37	0,5	neutral	0,2	neutral	0,12	neutral	0,36	neutral	0,27	5	neutral	0,63	neutral	0,43	neutral	-3	neutral	0,29	medium_impact	-1	medium_impact	0,24	medium_impact	-0,47	0,43	0,8	45,53	8,75	N	0,38	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15213	15213	T	C	MI.9319	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	467	156	I	T	aTt/aCt	1,33	0,72	0	probably_damaging	0,99	neutral	0,37	neutral	2,93	deleterious	-3,11	deleterious	-3,06	medium_impact	3,36	neutral	0,93	neutral	0,53	neutral	1,55	13,57	0,07	0,35	disease	0,59	disease	0,71	disease	0,56	disease	0,55	1	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,76	low_impact	-2,59	medium_impact	0,1	medium_impact	1,86	0,35	0,8	45,53	8,75	N	0,33	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8963	8963	C	T	MI.932	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	437	146	T	I	aCc/aTc	8,69	1	0	probably_damaging	1	neutral	0,08	neutral	4,43	neutral	1,18	deleterious	-5,54	medium_impact	2,4	neutral	0,71	neutral	0,52	deleterious	3,93	23,5	0,33	0,65	neutral	0,34	disease	0,84	disease	0,57	disease	0,64	3	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	-0,31	medium_impact	0,96	0,68	0,9	50	8,58	N	0,45	N	0,97	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15213	15213	T	A	MI.9320	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	467	156	I	N	aTt/aAt	1,33	0,72	0	probably_damaging	1	neutral	0,29	neutral	2,89	deleterious	-3,83	deleterious	-4,75	high_impact	4,95	neutral	0,93	neutral	0,41	deleterious	2,69	20,7	0,06	0,35	disease	0,81	disease	0,88	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,01	high_impact	3,3	0,21	0,8	45,53	8,75	P	0,66	P	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15213	15213	T	G	MI.9321	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	467	156	I	S	aTt/aGt	1,33	0,72	0	probably_damaging	0,99	neutral	0,39	neutral	2,92	deleterious	-3,27	deleterious	-3,92	high_impact	3,9	neutral	0,94	neutral	0,4	deleterious	2,51	19,51	0,03	0,35	disease	0,67	disease	0,83	disease	0,63	disease	0,59	2	deleterious	0,99	neutral	0,2	deleterious	2	deleterious	0,81	low_impact	-2,59	medium_impact	0,12	high_impact	2,35	0,24	0,8	45,53	8,75	N	0,38	N	0,98	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15214	15214	T	A	MI.9322	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	468	156	I	M	atT/atA	7,3	0,98	0	probably_damaging	0,99	neutral	0,22	neutral	2,93	deleterious	-3,26	neutral	-1,13	medium_impact	2,19	neutral	0,95	neutral	0,66	deleterious	0,71	8,91	0,22	0,45	neutral	0,4	neutral	0,43	neutral	0,38	neutral	0,45	1	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,67	low_impact	-2,59	medium_impact	-0,08	medium_impact	0,8	0,48	0,8	45,53	8,75	P	0,61	P	0,83	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15214	15214	T	G	MI.9323	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	468	156	I	M	atT/atG	7,3	0,98	0	probably_damaging	0,99	neutral	0,22	neutral	2,93	deleterious	-3,26	neutral	-1,13	medium_impact	2,19	neutral	0,95	neutral	0,66	deleterious	0,47	7,18	0,22	0,45	neutral	0,4	neutral	0,43	neutral	0,38	neutral	0,45	1	deleterious	0,99	neutral	0,12	deleterious	1	deleterious	0,67	low_impact	-2,59	medium_impact	-0,08	medium_impact	0,8	0,48	0,8	45,53	8,75	P	0,6	P	0,83	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15215	15215	G	C	MI.9324	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	469	157	G	R	Ggg/Cgg	-10,37	0	0	probably_damaging	1	neutral	0,35	neutral	2,64	deleterious	-8,38	deleterious	-6,49	high_impact	5,62	neutral	0,79	damaging	0,24	deleterious	3,86	23,5	0,02	0,35	disease	0,83	disease	0,93	disease	0,85	disease	0,72	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,53	medium_impact	0,08	high_impact	3,91	0,5	0,8	57,11	8,64	P	0,63	P	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15215	15215	G	T	MI.9325	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	469	157	G	W	Ggg/Tgg	-10,37	0	0	probably_damaging	1	neutral	0,19	neutral	2,6	deleterious	-11,15	deleterious	-6,5	high_impact	5,62	neutral	0,78	damaging	0,25	deleterious	4,33	24	0,04	0,35	disease	0,97	disease	0,95	disease	0,81	disease	0,63	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,12	high_impact	3,91	0,16	0,8	57,11	8,64	P	0,56	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15216	15216	G	T	MI.9326	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	470	157	G	V	gGg/gTg	4,08	1	0	probably_damaging	1	neutral	0,5	neutral	2,65	deleterious	-9,5	deleterious	-7,3	high_impact	5,28	neutral	0,79	neutral	0,37	deleterious	3,77	23,4	0,02	0,35	disease	0,73	disease	0,93	disease	0,78	disease	0,71	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,22	high_impact	3,6	0,16	0,8	57,11	8,64	P	0,6	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15216	15216	G	C	MI.9327	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	470	157	G	A	gGg/gCg	4,08	1	0	probably_damaging	1	neutral	0,51	neutral	2,68	deleterious	-6,84	deleterious	-4,85	high_impact	5,28	neutral	0,8	neutral	0,43	deleterious	3,01	22,3	0,04	0,35	neutral	0,46	disease	0,84	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,23	high_impact	3,6	0,4	0,8	57,11	8,64	P	0,7	P	0,83	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15216	15216	G	A	MI.9328	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	470	157	G	E	gGg/gAg	4,08	1	0	probably_damaging	1	neutral	0,27	neutral	2,66	deleterious	-7,9	deleterious	-6,49	high_impact	5,08	neutral	0,68	neutral	0,32	deleterious	3,9	23,5	0,03	0,35	disease	0,81	disease	0,93	disease	0,84	disease	0,75	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,01	high_impact	3,42	0,25	0,8	57,11	8,64	P	0,68	P	1	polymorphism	1	0,27	.	.	.	.	.	.	COSM1138302	.	.	.	.	.	.	.	.
chrM	15218	15218	A	C	MI.9329	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	472	158	T	P	Aca/Cca	-12,89	0	0,06	probably_damaging	0,99	neutral	0,23	neutral	3,05	neutral	-1,12	neutral	-1,53	low_impact	0,94	neutral	0,98	neutral	0,54	deleterious	1,96	15,95	0,07	0,35	NA	NA	disease	0,83	neutral	0,38	neutral	0,19	6	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,78	low_impact	-2,59	medium_impact	-0,06	medium_impact	-0,34	0,37	0,8	18,16	18,64	N	0,39	N	0,99	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8963	8963	C	G	MI.933	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	437	146	T	S	aCc/aGc	8,69	1	0	probably_damaging	0,99	neutral	0,14	neutral	4,22	neutral	-1,13	deleterious	-3,66	medium_impact	2,23	neutral	0,75	neutral	0,54	deleterious	3,46	23	0,5	0,65	disease	0,64	disease	0,55	neutral	0,46	neutral	0,45	1	deleterious	0,99	neutral	0,08	deleterious	1	deleterious	0,74	low_impact	-2,65	medium_impact	-0,15	medium_impact	0,81	0,77	0,9	50	8,58	P	0,57	P	0,88	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15218	15218	A	T	MI.9330	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	472	158	T	S	Aca/Tca	-12,89	0	0,06	probably_damaging	0,95	neutral	0,43	neutral	3,11	neutral	-0,61	neutral	-0,29	low_impact	1,15	neutral	0,98	neutral	0,94	deleterious	0,27	5,37	0,4	0,5	NA	NA	neutral	0,48	neutral	0,25	neutral	0,19	6	neutral	0,95	neutral	0,24	neutral	-2	deleterious	0,65	low_impact	-1,92	medium_impact	0,16	medium_impact	-0,15	0,63	0,8	18,16	18,64	N	0,41	N	0,63	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15218	15218	A	G	MI.9331	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	472	158	T	A	Aca/Gca	-12,89	0	0,06	probably_damaging	0,95	neutral	0,53	neutral	3,04	neutral	-0,76	neutral	-1,61	medium_impact	2,65	neutral	0,97	neutral	0,75	neutral	1,5	13,34	0,31	0,45	NA	NA	disease	0,6	neutral	0,37	neutral	0,37	3	neutral	0,95	neutral	0,29	deleterious	1	deleterious	0,66	low_impact	-1,92	medium_impact	0,25	medium_impact	1,21	0,28	0,8	18,16	18,64	N	0,26	N	0,91	polymorphism	1	0,01	rs2853506	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15219	15219	C	T	MI.9332	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	473	158	T	M	aCa/aTa	1,1	0	0	probably_damaging	1	neutral	0,23	neutral	2,98	deleterious	-3,01	neutral	-2,09	medium_impact	2,75	neutral	0,91	neutral	0,55	deleterious	3,89	23,5	0,13	0,4	NA	NA	disease	0,62	neutral	0,32	neutral	0,35	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,72	low_impact	-3,53	medium_impact	-0,06	medium_impact	1,3	0,43	0,8	18,16	18,64	N	0,41	N	0,98	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15219	15219	C	A	MI.9333	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	473	158	T	K	aCa/aAa	1,1	0	0	probably_damaging	0,99	neutral	0,31	neutral	3,07	neutral	-0,64	neutral	-1,15	low_impact	1,36	neutral	0,94	neutral	0,39	deleterious	2,58	19,96	0,11	0,4	NA	NA	disease	0,8	neutral	0,31	neutral	0,47	1	deleterious	0,99	neutral	0,16	neutral	-2	deleterious	0,78	low_impact	-2,59	medium_impact	0,03	medium_impact	0,04	0,43	0,8	18,16	18,64	N	0,33	N	0,96	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15221	15221	G	A	MI.9334	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	475	159	D	N	Gac/Aac	-11,51	0	0,01	benign	0,05	neutral	0,32	neutral	3,15	neutral	-0,53	neutral	0,33	low_impact	0,9	neutral	0,9	neutral	0,94	deleterious	2,38	18,67	0,56	0,6	neutral	0,41	disease	0,53	neutral	0,26	neutral	0,23	5	neutral	0,65	deleterious	0,64	neutral	-6	neutral	0,17	medium_impact	0,46	medium_impact	0,05	medium_impact	-0,38	0,71	0,85	11,58	18,84	N	0,44	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15221	15221	G	C	MI.9335	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	475	159	D	H	Gac/Cac	-11,51	0	0,01	probably_damaging	0,93	neutral	0,54	neutral	3,13	neutral	-1,21	neutral	-1,12	medium_impact	3,07	neutral	0,9	neutral	0,47	deleterious	3,56	23,1	0,1	0,4	neutral	0,45	disease	0,63	neutral	0,41	neutral	0,43	1	neutral	0,92	neutral	0,31	deleterious	1	deleterious	0,66	low_impact	-1,78	medium_impact	0,26	medium_impact	1,59	0,4	0,8	11,58	18,84	N	0,28	N	0,47	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15221	15221	G	T	MI.9336	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	475	159	D	Y	Gac/Tac	-11,51	0	0,01	probably_damaging	0,98	neutral	1	neutral	3,21	neutral	0,7	neutral	-1,53	medium_impact	2,46	neutral	0,91	neutral	0,61	deleterious	3,81	23,4	0,06	0,35	disease	0,7	disease	0,84	disease	0,52	disease	0,7	4	neutral	0,97	deleterious	0,51	deleterious	1	deleterious	0,79	low_impact	-2,31	high_impact	1,85	medium_impact	1,04	0,1	0,8	11,58	18,84	N	0,19	N	0,82	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15222	15222	A	C	MI.9337	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	476	159	D	A	gAc/gCc	-0,73	0	0	possibly_damaging	0,64	neutral	0,52	neutral	3,2	neutral	0,6	neutral	0,06	low_impact	1,21	neutral	0,91	neutral	0,66	deleterious	2,28	18	0,11	0,4	neutral	0,4	disease	0,6	neutral	0,48	neutral	0,21	6	neutral	0,61	neutral	0,44	neutral	-3	deleterious	0,51	medium_impact	-0,96	medium_impact	0,24	medium_impact	-0,1	0,26	0,8	11,58	18,84	N	0,31	N	0,24	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15222	15222	A	G	MI.9338	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	476	159	D	G	gAc/gGc	-0,73	0	0	possibly_damaging	0,52	neutral	0,35	neutral	3,17	neutral	-0,17	neutral	-1,04	medium_impact	2,63	neutral	0,84	neutral	0,52	deleterious	3,76	23,4	0,1	0,4	disease	0,56	disease	0,67	neutral	0,5	neutral	0,44	1	neutral	0,64	neutral	0,42	NA	0	neutral	0,4	medium_impact	-0,76	medium_impact	0,08	medium_impact	1,19	0,22	0,8	11,58	18,84	N	0,31	N	0,48	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15222	15222	A	T	MI.9339	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	476	159	D	V	gAc/gTc	-0,73	0	0	probably_damaging	0,9	neutral	0,51	neutral	3,16	neutral	-0,22	neutral	-0,48	medium_impact	2,9	neutral	0,9	neutral	0,7	deleterious	2,53	19,64	0,05	0,35	disease	0,56	disease	0,79	neutral	0,49	neutral	0,44	1	neutral	0,89	neutral	0,31	deleterious	1	deleterious	0,7	low_impact	-1,62	medium_impact	0,23	medium_impact	1,44	0,11	0,8	11,58	18,84	N	0,34	N	0,68	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8965	8965	A	T	MI.934	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	439	147	I	F	Atc/Ttc	-7,74	0	0	possibly_damaging	0,68	deleterious	0	neutral	3,85	deleterious	-3,23	deleterious	-3,55	medium_impact	2,86	neutral	0,82	neutral	0,42	deleterious	3,9	23,5	0,35	0,65	disease	0,57	disease	0,73	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,16	deleterious	4	deleterious	0,68	low_impact	-1,07	low_impact	-1,4	medium_impact	1,35	0,75	0,9	46,46	7,68	N	0,32	N	0,97	polymorphism	0,66	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15223	15223	C	A	MI.9340	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	477	159	D	E	gaC/gaA	-0,04	0	0,06	possibly_damaging	0,52	neutral	0,3	neutral	3,19	neutral	0,45	neutral	-0,28	low_impact	1,25	neutral	0,91	neutral	0,67	deleterious	2,85	21,6	0,2	0,45	neutral	0,32	disease	0,67	neutral	0,26	neutral	0,24	5	neutral	0,68	neutral	0,39	neutral	-3	neutral	0,41	medium_impact	-0,76	medium_impact	0,02	medium_impact	-0,06	0,69	0,85	11,58	18,84	N	0,41	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15223	15223	C	G	MI.9341	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	477	159	D	E	gaC/gaG	-0,04	0	0,06	possibly_damaging	0,52	neutral	0,3	neutral	3,19	neutral	0,45	neutral	-0,28	low_impact	1,25	neutral	0,91	neutral	0,67	deleterious	2,51	19,55	0,2	0,45	neutral	0,32	disease	0,67	neutral	0,26	neutral	0,24	5	neutral	0,68	neutral	0,39	neutral	-3	neutral	0,41	medium_impact	-0,76	medium_impact	0,02	medium_impact	-0,06	0,69	0,85	11,58	18,84	N	0,41	N	0,27	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15224	15224	C	G	MI.9342	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	478	160	L	V	Cta/Gta	-6,47	0	0	probably_damaging	0,98	neutral	0,54	neutral	2,69	neutral	-2,47	neutral	-2,25	medium_impact	3,08	neutral	0,94	damaging	0,11	neutral	1,68	14,29	0,19	0,45	NA	NA	disease	0,64	neutral	0,32	neutral	0,4	2	neutral	0,97	neutral	0,28	deleterious	1	deleterious	0,78	low_impact	-2,31	medium_impact	0,26	medium_impact	1,6	0,53	0,8	18,16	10,11	N	0,2	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15224	15224	C	A	MI.9343	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	478	160	L	M	Cta/Ata	-6,47	0	0	probably_damaging	1	neutral	0,23	neutral	2,61	deleterious	-3,45	neutral	-1,52	medium_impact	2,56	neutral	0,95	damaging	0,2	deleterious	3,7	23,3	0,19	0,45	NA	NA	disease	0,5	neutral	0,3	neutral	0,33	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,75	low_impact	-3,53	medium_impact	-0,06	medium_impact	1,13	0,59	0,8	18,16	10,11	N	0,39	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15225	15225	T	A	MI.9344	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	479	160	L	Q	cTa/cAa	-1,42	0	0	probably_damaging	1	neutral	0,31	neutral	2,57	deleterious	-6,25	deleterious	-4,79	high_impact	5,37	neutral	0,93	damaging	0,07	deleterious	4,02	23,6	0,01	0,35	NA	NA	disease	0,75	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,03	high_impact	3,68	0,29	0,8	18,16	10,11	P	0,58	P	0,98	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15225	15225	T	C	MI.9345	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	479	160	L	P	cTa/cCa	-1,42	0	0	probably_damaging	1	neutral	0,22	neutral	2,57	deleterious	-6,27	deleterious	-5,59	high_impact	4,82	neutral	0,93	damaging	0,06	deleterious	3,84	23,4	0,01	0,35	NA	NA	disease	0,81	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,08	high_impact	3,18	0,3	0,8	18,16	10,11	P	0,61	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15225	15225	T	G	MI.9346	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	479	160	L	R	cTa/cGa	-1,42	0	0	probably_damaging	1	neutral	0,34	neutral	2,58	deleterious	-5,87	deleterious	-4,81	high_impact	5,37	neutral	0,94	damaging	0,06	deleterious	4,09	23,7	0,01	0,35	NA	NA	disease	0,87	disease	0,73	disease	0,73	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,07	high_impact	3,68	0,16	0,8	18,16	10,11	P	0,66	P	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15227	15227	G	T	MI.9347	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	481	161	V	F	Gtt/Ttt	-2,8	0	0	probably_damaging	1	neutral	0,74	neutral	2,92	neutral	-2,98	deleterious	-4,08	high_impact	5,01	neutral	0,89	damaging	0,09	deleterious	3,79	23,4	0,02	0,35	disease	0,82	disease	0,92	disease	0,7	disease	0,67	3	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,47	high_impact	3,36	0,38	0,8	58,95	8,56	P	0,63	P	0,98	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15227	15227	G	A	MI.9348	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	481	161	V	I	Gtt/Att	-2,8	0	0	probably_damaging	0,99	neutral	0,43	neutral	3,04	neutral	-0,81	neutral	-0,82	high_impact	4,17	neutral	0,91	damaging	0,11	deleterious	1,9	15,6	0,45	0,55	neutral	0,45	disease	0,65	disease	0,58	disease	0,63	3	deleterious	0,99	neutral	0,22	deleterious	2	deleterious	0,63	low_impact	-2,59	medium_impact	0,16	high_impact	2,59	0,91	0,95	58,95	8,56	N	0,33	N	0,34	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15227	15227	G	C	MI.9349	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	481	161	V	L	Gtt/Ctt	-2,8	0	0	probably_damaging	0,99	neutral	0,79	neutral	3	neutral	-1,45	neutral	-2,44	high_impact	4,28	neutral	0,93	damaging	0,08	neutral	1,78	14,87	0,12	0,4	disease	0,52	disease	0,8	disease	0,56	disease	0,63	3	deleterious	0,99	neutral	0,4	deleterious	2	deleterious	0,8	low_impact	-2,59	medium_impact	0,53	high_impact	2,69	0,45	0,8	58,95	8,56	N	0,24	N	0,69	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8965	8965	A	G	MI.935	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	439	147	I	V	Atc/Gtc	-7,74	0	0	benign	0,01	neutral	0,49	neutral	4,15	neutral	-0,82	neutral	-0,79	low_impact	1,72	neutral	0,95	neutral	0,68	deleterious	2,02	16,36	0,57	0,65	neutral	0,5	neutral	0,32	neutral	0,42	neutral	0,28	4	neutral	0,5	deleterious	0,74	neutral	-6	neutral	0,17	medium_impact	1,14	medium_impact	0,28	medium_impact	0,38	0,66	0,9	46,46	7,68	N	0,27	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15228	15228	T	A	MI.9350	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	482	161	V	D	gTt/gAt	5,92	1	0	probably_damaging	1	neutral	0,23	neutral	2,9	deleterious	-3,7	deleterious	-5,71	high_impact	5,57	neutral	0,89	damaging	0,09	deleterious	4,57	24,4	0,01	0,35	disease	0,95	disease	0,88	disease	0,77	disease	0,63	3	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,06	high_impact	3,86	0,35	0,8	58,95	8,56	P	0,74	P	0,98	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15228	15228	T	C	MI.9351	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	482	161	V	A	gTt/gCt	5,92	1	0	probably_damaging	1	neutral	0,56	neutral	3,03	neutral	-0,84	deleterious	-3,25	high_impact	4,46	neutral	0,92	damaging	0,12	deleterious	3,42	23	0,05	0,35	disease	0,76	disease	0,73	disease	0,65	disease	0,66	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,28	high_impact	2,86	0,16	0,8	58,95	8,56	P	0,53	P	0,62	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15228	15228	T	G	MI.9352	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	482	161	V	G	gTt/gGt	5,92	1	0	probably_damaging	1	neutral	0,44	neutral	2,91	deleterious	-3,51	deleterious	-5,71	high_impact	4,76	neutral	0,92	damaging	0,11	deleterious	3,86	23,5	0,01	0,35	disease	0,92	disease	0,78	disease	0,7	disease	0,64	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,17	high_impact	3,13	0,32	0,8	58,95	8,56	P	0,72	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15230	15230	C	A	MI.9353	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	484	162	Q	K	Caa/Aaa	-5,55	0	0	probably_damaging	0,99	neutral	0,29	neutral	3,16	neutral	-0,15	neutral	-2,18	medium_impact	2,79	neutral	0,95	damaging	0,25	deleterious	2,1	16,89	0,2	0,45	neutral	0,23	disease	0,91	neutral	0,42	disease	0,63	3	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,78	low_impact	-2,59	medium_impact	0,01	medium_impact	1,34	0,31	0,8	21,05	36,92	N	0,31	N	0,52	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15230	15230	C	G	MI.9354	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	484	162	Q	E	Caa/Gaa	-5,55	0	0	probably_damaging	0,98	neutral	0,28	neutral	3,2	neutral	0,37	neutral	-0,79	neutral_impact	0,42	neutral	0,97	neutral	0,91	neutral	-1,41	0	0,31	0,45	neutral	0,15	neutral	0,38	neutral	0,32	neutral	0,39	2	deleterious	0,98	neutral	0,15	neutral	-2	deleterious	0,7	low_impact	-2,31	medium_impact	0	medium_impact	-0,81	0,29	0,8	21,05	36,92	N	0,37	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15231	15231	A	C	MI.9355	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	485	162	Q	P	cAa/cCa	0,87	0,57	0	probably_damaging	0,99	neutral	0,2	neutral	3,13	neutral	-0,69	deleterious	-3,78	high_impact	4,04	neutral	0,9	damaging	0,13	neutral	1,74	14,66	0,02	0,35	disease	0,51	disease	0,96	disease	0,7	disease	0,82	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-2,59	medium_impact	-0,1	high_impact	2,48	0,15	0,8	21,05	36,92	N	0,37	N	0,92	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15231	15231	A	G	MI.9356	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	485	162	Q	R	cAa/cGa	0,87	0,57	0	probably_damaging	0,99	neutral	0,34	neutral	3,15	neutral	-0,32	neutral	-2,42	high_impact	3,6	neutral	0,91	damaging	0,17	neutral	1,7	14,39	0,18	0,45	neutral	0,31	disease	0,93	disease	0,6	disease	0,67	3	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,83	low_impact	-2,59	medium_impact	0,07	high_impact	2,08	0,12	0,8	21,05	36,92	N	0,34	N	0,48	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15231	15231	A	T	MI.9357	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	485	162	Q	L	cAa/cTa	0,87	0,57	0	probably_damaging	0,99	neutral	0,65	neutral	3,09	neutral	-1,63	deleterious	-4,6	medium_impact	2,83	neutral	0,93	damaging	0,19	deleterious	2,06	16,58	0,05	0,35	neutral	0,22	disease	0,95	disease	0,54	disease	0,74	5	deleterious	0,99	neutral	0,33	deleterious	1	deleterious	0,8	low_impact	-2,59	medium_impact	0,37	medium_impact	1,38	0,08	0,8	21,05	36,92	N	0,23	N	0,85	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15232	15232	A	C	MI.9358	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	486	162	Q	H	caA/caC	4,31	0,99	0	probably_damaging	1	neutral	0,54	neutral	3,08	neutral	-2,17	deleterious	-2,79	medium_impact	3,4	neutral	0,89	damaging	0,2	deleterious	3,18	22,7	0,18	0,45	neutral	0,35	disease	0,88	disease	0,57	disease	0,7	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,81	low_impact	-3,53	medium_impact	0,26	medium_impact	1,89	0,43	0,8	21,05	36,92	N	0,41	N	0,48	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15232	15232	A	T	MI.9359	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	486	162	Q	H	caA/caT	4,31	0,99	0	probably_damaging	1	neutral	0,54	neutral	3,08	neutral	-2,17	deleterious	-2,79	medium_impact	3,4	neutral	0,89	damaging	0,2	deleterious	3,22	22,7	0,18	0,45	neutral	0,35	disease	0,88	disease	0,57	disease	0,7	4	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,81	low_impact	-3,53	medium_impact	0,26	medium_impact	1,89	0,43	0,8	21,05	36,92	N	0,42	N	0,48	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8965	8965	A	C	MI.936	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	439	147	I	L	Atc/Ctc	-7,74	0	0	benign	0,09	neutral	0,25	neutral	4,04	neutral	-1,4	neutral	-1,75	low_impact	1,25	neutral	0,81	neutral	0,53	deleterious	3,81	23,4	0,42	0,65	neutral	0,49	disease	0,54	neutral	0,38	neutral	0,45	1	neutral	0,72	deleterious	0,58	neutral	-6	neutral	0,24	medium_impact	0,2	medium_impact	0,02	medium_impact	-0,03	0,69	0,9	46,46	7,68	N	0,33	N	0,68	polymorphism	0,99	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15233	15233	T	C	MI.9360	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	487	163	W	R	Tga/Cga	0,64	0,99	0	probably_damaging	1	neutral	0,43	neutral	3,02	deleterious	-3,4	deleterious	-11,41	high_impact	4,79	neutral	0,68	damaging	0,06	deleterious	3,53	23,1	0,01	0,35	disease	0,89	disease	0,92	disease	0,82	disease	0,61	2	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0,16	high_impact	3,16	0,12	0,8	57,89	8,62	P	0,58	P	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15233	15233	T	G	MI.9361	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	487	163	W	G	Tga/Gga	0,64	0,99	0	probably_damaging	1	neutral	0,43	neutral	3,03	neutral	-2,58	deleterious	-10,59	high_impact	5,25	neutral	0,8	damaging	0,13	deleterious	3,65	23,2	0,02	0,35	disease	0,91	disease	0,85	disease	0,78	disease	0,63	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,16	high_impact	3,57	0,06	0,8	57,89	8,62	P	0,65	P	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15234	15234	G	T	MI.9362	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	488	163	W	L	tGa/tTa	5,69	1	0	probably_damaging	1	neutral	0,72	neutral	3,25	neutral	0,4	deleterious	-10,59	high_impact	4,31	neutral	0,8	damaging	0,08	deleterious	4	23,6	0,02	0,35	neutral	0,34	disease	0,88	disease	0,75	disease	0,68	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,44	high_impact	2,72	0,1	0,8	57,89	8,62	N	0,5	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15234	15234	G	C	MI.9363	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	488	163	W	S	tGa/tCa	5,69	1	0	probably_damaging	1	neutral	0,56	neutral	3,04	neutral	-2,28	deleterious	-11,39	high_impact	4,79	neutral	0,79	damaging	0,1	deleterious	3,83	23,4	0,02	0,35	disease	0,85	disease	0,92	disease	0,77	disease	0,63	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0,28	high_impact	3,16	0,05	0,8	57,89	8,62	P	0,65	P	0,99	disease_causing	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15235	15235	A	C	MI.9364	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	489	163	W	C	tgA/tgC	7,3	1	0,02	probably_damaging	1	neutral	0,18	neutral	3,02	deleterious	-3,77	deleterious	-10,6	high_impact	5,04	neutral	0,83	damaging	0,05	deleterious	3,92	23,5	0,02	0,35	disease	0,9	disease	0,92	disease	0,77	disease	0,61	2	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,14	high_impact	3,38	0,1	0,8	57,89	8,62	P	0,65	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15235	15235	A	T	MI.9365	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	489	163	W	C	tgA/tgT	7,3	1	0,02	probably_damaging	1	neutral	0,18	neutral	3,02	deleterious	-3,77	deleterious	-10,6	high_impact	5,04	neutral	0,83	damaging	0,05	deleterious	4,03	23,6	0,02	0,35	disease	0,9	disease	0,92	disease	0,77	disease	0,61	2	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,14	high_impact	3,38	0,1	0,8	57,89	8,62	P	0,66	P	1	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15236	15236	A	C	MI.9366	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	490	164	I	L	Atc/Ctc	1,33	0,99	0,04	benign	0,04	neutral	0,77	neutral	3,34	neutral	0,77	neutral	-1,23	low_impact	1,18	neutral	0,96	neutral	0,45	deleterious	1,93	15,75	0,25	0,45	neutral	0,16	disease	0,61	disease	0,51	neutral	0,22	6	neutral	0,16	deleterious	0,87	neutral	-6	neutral	0,11	medium_impact	0,56	medium_impact	0,51	medium_impact	-0,12	0,69	0,85	20	27,4	N	0,32	N	0,58	polymorphism	1	0,02	rs386829239	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15236	15236	A	T	MI.9367	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	490	164	I	F	Atc/Ttc	1,33	0,99	0,04	benign	0,29	neutral	0,75	neutral	3,02	neutral	-2,27	deleterious	-2,82	high_impact	3,65	neutral	0,95	neutral	0,42	deleterious	2,22	17,67	0,1	0,4	disease	0,55	disease	0,83	disease	0,75	disease	0,74	5	neutral	0,2	deleterious	0,73	neutral	-2	neutral	0,37	medium_impact	-0,37	medium_impact	0,48	high_impact	2,12	0,59	0,8	20	27,4	N	0,4	N	0,86	polymorphism	1	0,04	rs386829239	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15236	15236	A	G	MI.9368	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	490	164	I	V	Atc/Gtc	1,33	0,99	0,04	benign	0	neutral	0,62	neutral	3,18	neutral	-0,56	neutral	-0,43	low_impact	1,18	neutral	0,99	neutral	0,86	deleterious	-0,02	2,41	0,4	0,5	neutral	0,3	neutral	0,32	disease	0,54	neutral	0,41	2	neutral	0,38	deleterious	0,81	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,34	medium_impact	-0,12	0,5	0,8	20	27,4	N	0,39	N	0	polymorphism	1	0,01	rs386829239	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15237	15237	T	A	MI.9369	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	491	164	I	N	aTc/aAc	0,87	0,99	0	possibly_damaging	0,88	neutral	0,48	neutral	2,93	deleterious	-4,9	deleterious	-4,79	high_impact	5,1	neutral	0,93	neutral	0,41	deleterious	4,43	24,2	0,05	0,35	disease	0,73	disease	0,88	disease	0,74	disease	0,74	5	neutral	0,87	neutral	0,3	deleterious	1	deleterious	0,73	low_impact	-1,54	medium_impact	0,2	high_impact	3,44	0,19	0,8	20	27,4	P	0,7	P	0,95	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8966	8966	T	A	MI.937	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	440	147	I	N	aTc/aAc	5,68	1	0	probably_damaging	0,91	deleterious	0	neutral	3,77	deleterious	-6,39	deleterious	-6,09	high_impact	4,13	neutral	0,83	neutral	0,38	deleterious	4,46	24,2	0,31	0,65	disease	0,97	disease	0,74	disease	0,65	disease	0,81	6	deleterious	1	neutral	0,05	deleterious	6	deleterious	0,79	low_impact	-1,71	low_impact	-1,4	high_impact	2,44	0,55	0,9	46,46	7,68	N	0,5	N	0,99	polymorphism	0,79	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15237	15237	T	C	MI.9370	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	491	164	I	T	aTc/aCc	0,87	0,99	0	benign	0,28	neutral	0,6	neutral	2,97	deleterious	-3,08	deleterious	-2,99	high_impact	4,75	neutral	0,97	neutral	0,45	deleterious	3,06	22,4	0,03	0,35	disease	0,51	disease	0,77	disease	0,68	disease	0,56	1	neutral	0,3	deleterious	0,66	neutral	-2	neutral	0,29	medium_impact	-0,35	medium_impact	0,32	high_impact	3,12	0,37	0,8	20	27,4	P	0,53	P	0,9	polymorphism	1	0,16	rs879217377	.	.	.	.	.	.	.	0,15	T15237C	Potentially functional variant cosegregating with LHON 3635A	+	-	Reported	1
chrM	15237	15237	T	G	MI.9371	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	491	164	I	S	aTc/aGc	0,87	0,99	0	possibly_damaging	0,56	neutral	0,66	neutral	2,96	deleterious	-4,05	deleterious	-3,77	high_impact	4,75	neutral	0,94	neutral	0,39	deleterious	3,98	23,6	0,02	0,35	disease	0,57	disease	0,86	disease	0,73	disease	0,74	5	neutral	0,48	deleterious	0,55	deleterious	1	deleterious	0,54	medium_impact	-0,83	medium_impact	0,38	high_impact	3,12	0,19	0,8	20	27,4	P	0,61	P	0,88	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15238	15238	C	A	MI.9372	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	492	164	I	M	atC/atA	3,63	0,99	0	possibly_damaging	0,61	neutral	0,27	neutral	2,96	neutral	-2,23	neutral	-1,88	high_impact	3,68	neutral	0,91	neutral	0,42	deleterious	3,36	22,9	0,18	0,45	neutral	0,39	disease	0,63	disease	0,57	disease	0,61	2	neutral	0,74	neutral	0,33	deleterious	1	neutral	0,35	medium_impact	-0,91	medium_impact	-0,01	high_impact	2,15	0,6	0,8	20	27,4	N	0,54	P	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15238	15238	C	G	MI.9373	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	492	164	I	M	atC/atG	3,63	0,99	0	possibly_damaging	0,61	neutral	0,27	neutral	2,96	neutral	-2,23	neutral	-1,88	high_impact	3,68	neutral	0,91	neutral	0,42	deleterious	3	22,2	0,18	0,45	neutral	0,39	disease	0,63	disease	0,57	disease	0,61	2	neutral	0,74	neutral	0,33	deleterious	1	neutral	0,35	medium_impact	-0,91	medium_impact	-0,01	high_impact	2,15	0,6	0,8	20	27,4	N	0,54	P	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15239	15239	T	C	MI.9374	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	493	165	W	R	Tga/Cga	-2,11	0	0	probably_damaging	1	neutral	0,36	neutral	3,09	neutral	-2,13	deleterious	-11,44	high_impact	4,32	neutral	0,65	damaging	0,06	deleterious	3,53	23,1	0,02	0,35	disease	0,68	disease	0,91	disease	0,84	disease	0,73	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,09	high_impact	2,73	0,09	0,8	58,42	8,75	N	0,49	N	0,99	polymorphism	1	0,1	.	.	.	.	.	.	COSM1138304	.	.	.	.	.	.	.	.
chrM	15239	15239	T	G	MI.9375	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	493	165	W	G	Tga/Gga	-2,11	0	0	probably_damaging	1	neutral	0,36	neutral	3,09	neutral	-2,2	deleterious	-10,63	high_impact	5,05	neutral	0,75	damaging	0,13	deleterious	3,83	23,4	0,02	0,35	disease	0,76	disease	0,84	disease	0,82	disease	0,68	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,09	high_impact	3,39	0,04	0,8	58,42	8,75	P	0,66	P	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15240	15240	G	C	MI.9376	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	494	165	W	S	tGa/tCa	5,69	1	0	probably_damaging	1	neutral	0,42	neutral	3,12	neutral	-1,19	deleterious	-11,42	high_impact	4,63	neutral	0,85	damaging	0,11	deleterious	3,95	23,6	0,02	0,35	disease	0,63	disease	0,92	disease	0,8	disease	0,71	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,15	high_impact	3,01	0,05	0,8	58,42	8,75	P	0,63	P	0,99	disease_causing	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15240	15240	G	T	MI.9377	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	494	165	W	L	tGa/tTa	5,69	1	0	probably_damaging	1	neutral	0,67	neutral	3,32	neutral	1,36	deleterious	-10,62	high_impact	4,29	neutral	0,75	damaging	0,08	deleterious	4,23	23,9	0,03	0,35	neutral	0,44	disease	0,86	disease	0,8	disease	0,68	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,39	high_impact	2,7	0,08	0,8	58,42	8,75	P	0,54	P	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15241	15241	A	C	MI.9378	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	495	165	W	C	tgA/tgC	7,07	1	0	probably_damaging	1	neutral	0,18	neutral	3,09	neutral	-2,03	deleterious	-10,64	high_impact	4,41	neutral	0,77	damaging	0,05	deleterious	4,01	23,6	0,02	0,35	disease	0,59	disease	0,92	disease	0,83	disease	0,73	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,14	high_impact	2,81	0,11	0,8	58,42	8,75	P	0,55	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15241	15241	A	T	MI.9379	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	495	165	W	C	tgA/tgT	7,07	1	0	probably_damaging	1	neutral	0,18	neutral	3,09	neutral	-2,03	deleterious	-10,64	high_impact	4,41	neutral	0,77	damaging	0,05	deleterious	4,12	23,8	0,02	0,35	disease	0,59	disease	0,92	disease	0,83	disease	0,73	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,14	high_impact	2,81	0,11	0,8	58,42	8,75	P	0,56	P	1	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8966	8966	T	C	MI.938	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	440	147	I	T	aTc/aCc	5,68	1	0	benign	0,39	neutral	0,08	neutral	3,82	deleterious	-3,87	deleterious	-4,08	medium_impact	2,25	neutral	0,88	neutral	0,62	deleterious	3,4	23	0,53	0,65	disease	0,87	neutral	0,49	neutral	0,49	disease	0,61	2	neutral	0,91	neutral	0,35	neutral	-3	deleterious	0,55	medium_impact	-0,57	medium_impact	-0,31	medium_impact	0,83	0,62	0,9	46,46	7,68	P	0,57	P	0,99	polymorphism	0,92	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15242	15242	G	T	MI.9380	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	496	166	G	W	Gga/Tga	4,77	1	0	probably_damaging	1	neutral	0,22	neutral	2,29	deleterious	-8,67	deleterious	-6,58	high_impact	5,63	neutral	0,84	damaging	0,05	deleterious	4,5	24,3	0,02	0,35	disease	0,97	disease	0,91	disease	0,85	disease	0,67	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	-0,08	high_impact	3,92	0,07	0,8	58,16	8,83	P	0,64	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15242	15242	G	C	MI.9381	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	496	166	G	R	Gga/Cga	4,77	1	0	probably_damaging	1	neutral	0,35	neutral	2,33	deleterious	-5,52	deleterious	-6,56	high_impact	5,29	neutral	0,83	damaging	0,04	deleterious	3,98	23,6	0,03	0,35	disease	0,86	disease	0,89	disease	0,86	disease	0,68	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,92	low_impact	-3,53	medium_impact	0,08	high_impact	3,61	0,43	0,8	58,16	8,83	P	0,75	P	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15243	15243	G	T	MI.9382	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	497	166	G	V	gGa/gTa	9,13	1	0	probably_damaging	1	neutral	0,52	neutral	2,33	deleterious	-5,15	deleterious	-7,38	high_impact	5,29	neutral	0,84	damaging	0,07	deleterious	3,77	23,4	0,03	0,35	disease	0,77	disease	0,9	disease	0,83	disease	0,73	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,24	high_impact	3,61	0,17	0,8	58,16	8,83	P	0,74	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15243	15243	G	A	MI.9383	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	497	166	G	E	gGa/gAa	9,13	1	0	probably_damaging	1	neutral	0,28	neutral	2,35	deleterious	-4,72	deleterious	-6,56	high_impact	5,29	neutral	0,82	damaging	0,05	deleterious	3,89	23,5	0,03	0,35	disease	0,83	disease	0,89	disease	0,87	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	0	high_impact	3,61	0,22	0,8	58,16	8,83	P	0,82	P	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	G15243A	HCM	-	+	Reported	3
chrM	15243	15243	G	C	MI.9384	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	497	166	G	A	gGa/gCa	9,13	1	0	probably_damaging	1	neutral	0,52	neutral	2,39	deleterious	-3,73	deleterious	-4,91	high_impact	5,29	neutral	0,84	damaging	0,1	deleterious	3,09	22,5	0,03	0,35	disease	0,6	disease	0,8	disease	0,82	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,24	high_impact	3,61	0,28	0,8	58,16	8,83	P	0,77	P	0,83	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15245	15245	G	A	MI.9385	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	499	167	G	S	Ggc/Agc	-20	0	0	probably_damaging	1	neutral	0,43	neutral	2,94	neutral	-2,7	deleterious	-4,91	high_impact	4,08	neutral	0,79	neutral	0,35	deleterious	4,14	23,8	0,03	0,35	disease	0,72	disease	0,82	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,16	high_impact	2,51	0,64	0,8	56,05	8,33	N	0,28	N	1	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15245	15245	G	C	MI.9386	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	499	167	G	R	Ggc/Cgc	-20	0	0	probably_damaging	1	neutral	0,35	neutral	2,86	deleterious	-4,08	deleterious	-6,56	high_impact	5,59	neutral	0,79	damaging	0,22	deleterious	3,97	23,6	0,02	0,35	disease	0,9	disease	0,86	disease	0,82	disease	0,63	3	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,91	low_impact	-3,53	medium_impact	0,08	high_impact	3,88	0,55	0,8	56,05	8,33	P	0,67	P	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15245	15245	G	T	MI.9387	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	499	167	G	C	Ggc/Tgc	-20	0	0	probably_damaging	1	neutral	0,17	neutral	2,8	deleterious	-6,87	deleterious	-7,4	high_impact	5,25	neutral	0,79	damaging	0,22	deleterious	4,2	23,9	0,02	0,35	disease	0,92	disease	0,89	disease	0,72	disease	0,6	2	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,9	low_impact	-3,53	medium_impact	-0,15	high_impact	3,57	0,23	0,8	56,05	8,33	N	0,55	P	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15246	15246	G	C	MI.9388	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	500	167	G	A	gGc/gCc	7,07	1	0	probably_damaging	1	neutral	0,51	neutral	2,87	deleterious	-3,83	deleterious	-4,91	high_impact	4,9	neutral	0,89	neutral	0,44	deleterious	3,04	22,4	0,04	0,35	disease	0,7	disease	0,74	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,23	high_impact	3,26	0,42	0,8	56,05	8,33	P	0,72	P	0,83	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15246	15246	G	A	MI.9389	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	500	167	G	D	gGc/gAc	7,07	1	0	probably_damaging	1	neutral	0,2	neutral	2,9	neutral	-2,51	deleterious	-5,74	high_impact	3,54	neutral	0,72	damaging	0,28	deleterious	3,82	23,4	0,02	0,35	disease	0,88	disease	0,86	disease	0,8	disease	0,64	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,1	high_impact	2,02	0,15	0,8	56,05	8,33	P	0,6	P	1	polymorphism	1	0,1	rs1057516075	Likely pathogenic|Likely pathogenic|Likely pathogenic	Developmental_delay|Hearing_impairment|Macrocephaly	RCV000408934.1|RCV000408934.1|RCV000408934.1	MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen:OMIM	.	.	.	.	.	.	.	.	.	.
chrM	8966	8966	T	G	MI.939	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	440	147	I	S	aTc/aGc	5,68	1	0	possibly_damaging	0,68	deleterious	0	neutral	3,79	deleterious	-5,23	deleterious	-5,13	high_impact	3,79	neutral	0,82	neutral	0,44	deleterious	4,32	24	0,29	0,65	disease	0,94	disease	0,79	disease	0,64	disease	0,81	6	deleterious	1	neutral	0,16	deleterious	5	deleterious	0,65	low_impact	-1,07	low_impact	-1,4	high_impact	2,15	0,54	0,9	46,46	7,68	P	0,51	P	0,95	polymorphism	0,75	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15246	15246	G	T	MI.9390	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	500	167	G	V	gGc/gTc	7,07	1	0	probably_damaging	1	neutral	0,52	neutral	2,83	deleterious	-6,12	deleterious	-7,38	high_impact	5,59	neutral	0,79	neutral	0,36	deleterious	3,75	23,3	0,02	0,35	disease	0,83	disease	0,86	disease	0,74	disease	0,67	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,24	high_impact	3,88	0,14	0,8	56,05	8,33	P	0,71	P	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15248	15248	T	A	MI.9391	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	502	168	Y	N	Tac/Aac	-15,18	0	0	probably_damaging	1	neutral	0,32	neutral	3,17	neutral	-1,07	deleterious	-5,12	medium_impact	2,39	neutral	0,92	neutral	0,61	deleterious	3,92	23,5	0,07	0,35	disease	0,86	disease	0,8	disease	0,66	disease	0,72	4	deleterious	1	neutral	0,16	deleterious	1	deleterious	0,86	low_impact	-3,53	medium_impact	0,05	medium_impact	0,98	0,14	0,8	21,58	50,18	N	0,34	N	0,83	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15248	15248	T	G	MI.9392	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	502	168	Y	D	Tac/Gac	-15,18	0	0	probably_damaging	1	neutral	0,22	neutral	3,2	neutral	-0,9	deleterious	-5,19	medium_impact	2,04	neutral	0,9	neutral	0,43	deleterious	3,85	23,4	0,03	0,35	disease	0,93	disease	0,79	disease	0,75	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,88	low_impact	-3,53	medium_impact	-0,08	medium_impact	0,66	0,12	0,8	21,58	50,18	N	0,37	N	0,94	disease_causing	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15248	15248	T	C	MI.9393	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	502	168	Y	H	Tac/Cac	-15,18	0	0	probably_damaging	1	neutral	0,54	neutral	3,1	neutral	-1,68	deleterious	-3,34	low_impact	1,64	neutral	0,92	neutral	0,47	deleterious	3,42	23	0,13	0,4	disease	0,73	disease	0,53	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,81	low_impact	-3,53	medium_impact	0,26	medium_impact	0,3	0,25	0,8	21,58	50,18	N	0,28	N	0,79	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15249	15249	A	T	MI.9394	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	503	168	Y	F	tAc/tTc	4,54	1	0	probably_damaging	1	neutral	0,76	neutral	3,17	neutral	1,79	neutral	1,96	neutral_impact	-2,82	neutral	0,96	neutral	0,91	neutral	-0,86	0,03	0,3	0,45	neutral	0,19	neutral	0,1	neutral	0,19	neutral	0,27	5	deleterious	1	neutral	0,38	neutral	-2	deleterious	0,66	low_impact	-3,53	medium_impact	0,49	low_impact	-3,75	0,47	0,8	21,58	50,18	N	0,48	N	0,07	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15249	15249	A	G	MI.9395	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	503	168	Y	C	tAc/tGc	4,54	1	0	probably_damaging	1	neutral	0,18	neutral	3,08	neutral	-2,79	deleterious	-4,38	medium_impact	2,19	neutral	0,95	neutral	0,42	deleterious	3,47	23	0,03	0,35	disease	0,94	disease	0,78	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,87	low_impact	-3,53	medium_impact	-0,14	medium_impact	0,8	0,09	0,8	21,58	50,18	N	0,45	N	0,81	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15249	15249	A	C	MI.9396	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	503	168	Y	S	tAc/tCc	4,54	1	0	probably_damaging	1	neutral	0,44	neutral	3,18	neutral	-0,61	deleterious	-4,35	medium_impact	2,04	neutral	0,95	neutral	0,58	deleterious	3,51	23,1	0,05	0,35	disease	0,85	disease	0,66	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,86	low_impact	-3,53	medium_impact	0,17	medium_impact	0,66	0,22	0,8	21,58	50,18	N	0,49	N	0,84	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15251	15251	T	G	MI.9397	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	505	169	S	A	Tca/Gca	-4,4	0	0	benign	0,07	neutral	0,52	neutral	3,18	neutral	-0,9	neutral	-1,78	low_impact	1,88	neutral	0,95	damaging	0,23	deleterious	0,76	9,18	0,15	0,4	neutral	0,41	disease	0,51	neutral	0,36	neutral	0,21	6	neutral	0,42	deleterious	0,73	neutral	-6	neutral	0,21	medium_impact	0,32	medium_impact	0,24	medium_impact	0,51	0,44	0,8	17,63	16,71	N	0,26	N	0,11	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15251	15251	T	A	MI.9398	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	505	169	S	T	Tca/Aca	-4,4	0	0	benign	0,07	neutral	0,46	neutral	3,19	neutral	-1,52	neutral	-2,23	high_impact	3,69	neutral	0,97	damaging	0,15	deleterious	2,04	16,45	0,17	0,45	neutral	0,35	disease	0,69	disease	0,59	disease	0,63	3	neutral	0,48	deleterious	0,7	neutral	-2	neutral	0,22	medium_impact	0,32	medium_impact	0,18	high_impact	2,16	0,5	0,8	17,63	16,71	N	0,33	N	0,66	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15251	15251	T	C	MI.9399	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	505	169	S	P	Tca/Cca	-4,4	0	0	benign	0,01	neutral	0,23	neutral	3,06	deleterious	-3,12	deleterious	-3,78	high_impact	4,88	neutral	0,94	damaging	0,08	deleterious	2,36	18,59	0,06	0,35	disease	0,76	disease	0,84	disease	0,61	disease	0,66	3	neutral	0,77	deleterious	0,61	neutral	-2	neutral	0,31	medium_impact	1,13	medium_impact	-0,06	high_impact	3,24	0,2	0,8	17,63	16,71	P	0,57	P	0,93	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8568	8568	C	A	MI.94	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	42	14	I	M	atC/atA	1,75	0,01	0	possibly_damaging	0,82	neutral	0,26	neutral	4,59	neutral	-1,38	neutral	-0,03	neutral_impact	0,62	neutral	0,91	neutral	0,9	deleterious	4,37	24,1	0,62	0,7	neutral	0,37	neutral	0,21	neutral	0,32	neutral	0,36	3	neutral	0,87	neutral	0,22	neutral	-3	deleterious	0,53	low_impact	-1,38	medium_impact	0,04	medium_impact	-0,57	0,83	0,9	13,72	12,42	P	0,54	P	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8967	8967	C	A	MI.940	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	441	147	I	M	atC/atA	4,76	1	0	possibly_damaging	0,82	neutral	0,05	neutral	3,8	deleterious	-4,42	deleterious	-2,6	medium_impact	2,66	neutral	0,91	neutral	0,51	deleterious	3,77	23,4	0,48	0,65	disease	0,84	disease	0,51	disease	0,56	disease	0,6	2	neutral	0,97	neutral	0,12	NA	0	deleterious	0,7	low_impact	-1,38	medium_impact	-0,43	medium_impact	1,18	0,86	0,9	46,46	7,68	P	0,53	P	0,8	polymorphism	0,97	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15252	15252	C	G	MI.9400	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	506	169	S	W	tCa/tGa	4,54	1	0	probably_damaging	0,96	neutral	0,27	neutral	3,05	deleterious	-3,91	deleterious	-5,42	high_impact	5,42	neutral	0,96	damaging	0,09	deleterious	4,31	24	0,06	0,35	disease	0,94	disease	0,9	disease	0,75	disease	0,64	3	neutral	0,97	neutral	0,16	deleterious	2	deleterious	0,84	low_impact	-2,02	medium_impact	-0,01	high_impact	3,73	0,16	0,8	17,63	16,71	P	0,69	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15252	15252	C	T	MI.9401	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	506	169	S	L	tCa/tTa	4,54	1	0	benign	0,41	neutral	0,74	neutral	3,14	neutral	-1,03	deleterious	-4,47	high_impact	4,28	neutral	0,95	damaging	0,06	deleterious	4,32	24	0,05	0,35	disease	0,68	disease	0,86	disease	0,68	disease	0,7	4	neutral	0,31	deleterious	0,67	neutral	-2	deleterious	0,59	medium_impact	-0,58	medium_impact	0,47	high_impact	2,69	0,55	0,8	17,63	16,71	N	0,43	N	0,93	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15254	15254	G	T	MI.9402	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	508	170	V	L	Gta/Tta	-3,03	0	0	probably_damaging	0,98	neutral	0,68	neutral	3,08	neutral	-1,45	neutral	-2,29	high_impact	4,38	neutral	0,91	neutral	0,42	deleterious	1,88	15,48	0,12	0,4	disease	0,52	disease	0,77	disease	0,73	disease	0,69	4	neutral	0,98	neutral	0,35	deleterious	2	deleterious	0,78	low_impact	-2,31	medium_impact	0,4	high_impact	2,78	0,32	0,8	20,53	43,28	N	0,36	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15254	15254	G	A	MI.9403	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	508	170	V	M	Gta/Ata	-3,03	0	0	probably_damaging	1	neutral	0,22	neutral	2,97	deleterious	-3,41	neutral	-2,38	high_impact	5,49	neutral	0,84	neutral	0,43	deleterious	3,63	23,2	0,1	0,4	neutral	0,43	disease	0,74	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,73	low_impact	-3,53	medium_impact	-0,08	high_impact	3,79	0,58	0,8	20,53	43,28	P	0,71	P	0,84	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15254	15254	G	C	MI.9404	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	508	170	V	L	Gta/Cta	-3,03	0	0	probably_damaging	0,98	neutral	0,68	neutral	3,08	neutral	-1,45	neutral	-2,29	high_impact	4,38	neutral	0,91	neutral	0,42	neutral	1,77	14,83	0,12	0,4	disease	0,52	disease	0,77	disease	0,73	disease	0,69	4	neutral	0,98	neutral	0,35	deleterious	2	deleterious	0,78	low_impact	-2,31	medium_impact	0,4	high_impact	2,78	0,32	0,8	20,53	43,28	N	0,36	N	0,7	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15255	15255	T	A	MI.9405	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	509	170	V	E	gTa/gAa	7,3	1	0	probably_damaging	1	neutral	0,27	neutral	2,97	deleterious	-4,4	deleterious	-4,92	high_impact	5,49	neutral	0,89	neutral	0,42	deleterious	4,75	24,7	0,02	0,35	disease	0,93	disease	0,88	disease	0,84	disease	0,7	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,01	high_impact	3,79	0,24	0,8	20,53	43,28	P	0,81	P	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15255	15255	T	C	MI.9406	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	509	170	V	A	gTa/gCa	7,3	1	0	probably_damaging	1	neutral	0,56	neutral	3,04	neutral	-2,56	deleterious	-3,26	high_impact	4,59	neutral	0,91	neutral	0,51	deleterious	3,34	22,9	0,06	0,35	disease	0,76	disease	0,73	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,28	high_impact	2,97	0,22	0,8	20,53	43,28	P	0,63	P	0,83	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15255	15255	T	G	MI.9407	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	509	170	V	G	gTa/gGa	7,3	1	0	probably_damaging	1	neutral	0,4	neutral	2,98	deleterious	-3,22	deleterious	-5,74	high_impact	4,79	neutral	0,9	neutral	0,48	deleterious	3,72	23,3	0,02	0,35	disease	0,92	disease	0,8	disease	0,77	disease	0,67	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,13	high_impact	3,16	0,24	0,8	20,53	43,28	P	0,74	P	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15257	15257	G	T	MI.9408	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	511	171	D	Y	Gac/Tac	-4,4	0	0,03	possibly_damaging	0,88	neutral	1	neutral	3,1	deleterious	-3,59	deleterious	-6,97	high_impact	4,7	neutral	0,91	neutral	0,43	deleterious	3,85	23,4	0,03	0,35	disease	0,75	disease	0,94	disease	0,79	disease	0,79	6	neutral	0,88	deleterious	0,56	deleterious	1	deleterious	0,83	low_impact	-1,54	high_impact	1,85	high_impact	3,07	0,12	0,8	19,74	12,46	P	0,53	P	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15257	15257	G	A	MI.9409	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	511	171	D	N	Gac/Aac	-4,4	0	0,03	benign	0,01	neutral	0,35	neutral	3,2	neutral	-0,15	deleterious	-3,57	medium_impact	2	damaging	0,49	neutral	0,53	deleterious	3,86	23,5	0,32	0,5	neutral	0,34	disease	0,84	disease	0,6	neutral	0,38	2	neutral	0,64	deleterious	0,67	neutral	-3	neutral	0,24	medium_impact	1,13	medium_impact	0,08	medium_impact	0,62	0,76	0,85	19,74	12,46	N	0,43	N	0,25	polymorphism	1	0,04	rs41518645	other	Leber's_optic_atrophy	RCV000010312.4	MedGen:OMIM:SNOMED_CT	.	COSM1138306	.	.	G15257A	LHON	+	-	P.M.-haplogroup J2 marker-possible helper mut.	44
chrM	8967	8967	C	G	MI.941	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	441	147	I	M	atC/atG	4,76	1	0	possibly_damaging	0,82	neutral	0,05	neutral	3,8	deleterious	-4,42	deleterious	-2,6	medium_impact	2,66	neutral	0,91	neutral	0,51	deleterious	3,34	22,9	0,48	0,65	disease	0,84	disease	0,51	disease	0,56	disease	0,6	2	neutral	0,97	neutral	0,12	NA	0	deleterious	0,7	low_impact	-1,38	medium_impact	-0,43	medium_impact	1,18	0,86	0,9	46,46	7,68	N	0,53	P	0,8	polymorphism	0,97	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15257	15257	G	C	MI.9410	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	511	171	D	H	Gac/Cac	-4,4	0	0,03	possibly_damaging	0,69	neutral	0,55	neutral	3,12	neutral	-2,66	deleterious	-5,31	high_impact	4,28	neutral	0,87	neutral	0,35	deleterious	3,53	23,1	0,05	0,35	disease	0,64	disease	0,87	disease	0,76	disease	0,73	5	neutral	0,65	neutral	0,43	deleterious	1	deleterious	0,64	low_impact	-1,06	medium_impact	0,27	high_impact	2,69	0,43	0,8	19,74	12,46	N	0,38	N	0,89	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15258	15258	A	C	MI.9411	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	512	171	D	A	gAc/gCc	5,92	1	0	benign	0,11	neutral	0,58	neutral	3,21	neutral	-1,63	deleterious	-6,13	high_impact	4,35	neutral	0,91	neutral	0,46	deleterious	3,32	22,9	0,04	0,35	neutral	0,44	disease	0,87	disease	0,76	disease	0,72	4	neutral	0,33	deleterious	0,74	neutral	-2	neutral	0,31	medium_impact	0,12	medium_impact	0,3	high_impact	2,76	0,35	0,8	19,74	12,46	P	0,6	P	0,84	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15258	15258	A	G	MI.9412	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	512	171	D	G	gAc/gGc	5,92	1	0	benign	0,01	neutral	0,38	neutral	3,31	neutral	-0,07	deleterious	-5,24	medium_impact	2,74	neutral	0,82	neutral	0,54	deleterious	3,74	23,3	0,05	0,35	disease	0,58	disease	0,84	disease	0,75	disease	0,6	2	neutral	0,61	deleterious	0,69	neutral	-3	neutral	0,26	medium_impact	1,13	medium_impact	0,11	medium_impact	1,29	0,28	0,8	19,74	12,46	P	0,54	P	0,8	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15258	15258	A	T	MI.9413	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	512	171	D	V	gAc/gTc	5,92	1	0	possibly_damaging	0,51	neutral	0,55	neutral	3,11	deleterious	-3,95	deleterious	-7,01	high_impact	4,9	neutral	0,91	neutral	0,48	deleterious	3,64	23,2	0,02	0,35	disease	0,64	disease	0,92	disease	0,77	disease	0,74	5	neutral	0,47	deleterious	0,52	deleterious	1	deleterious	0,62	medium_impact	-0,75	medium_impact	0,27	high_impact	3,26	0,1	0,8	19,74	12,46	P	0,65	P	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15259	15259	C	A	MI.9414	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	513	171	D	E	gaC/gaA	5,46	1	0	benign	0,04	neutral	0,35	neutral	3,19	neutral	-1,12	deleterious	-3,07	high_impact	4,04	neutral	0,89	neutral	0,43	deleterious	2,39	18,74	0,17	0,45	neutral	0,29	disease	0,81	disease	0,67	disease	0,67	3	neutral	0,62	deleterious	0,66	neutral	-2	neutral	0,23	medium_impact	0,56	medium_impact	0,08	high_impact	2,48	0,45	0,8	19,74	12,46	P	0,62	P	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15259	15259	C	G	MI.9415	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	513	171	D	E	gaC/gaG	5,46	1	0	benign	0,04	neutral	0,35	neutral	3,19	neutral	-1,12	deleterious	-3,07	high_impact	4,04	neutral	0,89	neutral	0,43	deleterious	2,07	16,65	0,17	0,45	neutral	0,29	disease	0,81	disease	0,67	disease	0,67	3	neutral	0,62	deleterious	0,66	neutral	-2	neutral	0,23	medium_impact	0,56	medium_impact	0,08	high_impact	2,48	0,45	0,8	19,74	12,46	P	0,62	P	0,85	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15260	15260	A	C	MI.9416	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	514	172	S	R	Agt/Cgt	-0,5	0,13	0	benign	0,36	neutral	0,35	neutral	3,1	neutral	-1,32	neutral	-0,54	medium_impact	2,27	neutral	0,95	neutral	0,53	deleterious	3,36	22,9	0,14	0,4	neutral	0,31	disease	0,85	disease	0,63	disease	0,77	5	neutral	0,58	deleterious	0,5	neutral	-3	deleterious	0,45	medium_impact	-0,5	medium_impact	0,08	medium_impact	0,87	0,4	0,8	21,32	51,81	N	0,35	N	0,46	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15260	15260	A	T	MI.9417	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	514	172	S	C	Agt/Tgt	-0,5	0,13	0	probably_damaging	0,92	neutral	0,18	neutral	3,04	deleterious	-4,39	deleterious	-3,17	low_impact	1,92	neutral	0,95	neutral	0,44	deleterious	3,21	22,7	0,1	0,4	disease	0,78	disease	0,78	disease	0,51	disease	0,61	2	neutral	0,96	neutral	0,13	neutral	-2	deleterious	0,76	low_impact	-1,72	medium_impact	-0,14	medium_impact	0,55	0,28	0,8	21,32	51,81	N	0,41	N	0,73	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15260	15260	A	G	MI.9418	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	514	172	S	G	Agt/Ggt	-0,5	0,13	0	benign	0,17	neutral	0,34	neutral	3,12	neutral	-0,23	neutral	-1,19	neutral_impact	0,22	neutral	0,94	neutral	0,58	neutral	1,78	14,84	0,22	0,45	neutral	0,31	disease	0,52	neutral	0,38	neutral	0,45	1	neutral	0,6	deleterious	0,59	neutral	-6	neutral	0,25	medium_impact	-0,09	medium_impact	0,07	medium_impact	-0,99	0,51	0,8	21,32	51,81	N	0,37	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15261	15261	G	A	MI.9419	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	515	172	S	N	aGt/aAt	5,46	1	0	benign	0,01	neutral	0,33	neutral	3,19	neutral	1,2	neutral	2,69	neutral_impact	-3	neutral	0,92	neutral	0,8	neutral	1,23	11,89	0,52	0,6	neutral	0,17	neutral	0,14	neutral	0,16	neutral	0,24	5	neutral	0,66	deleterious	0,66	neutral	-6	neutral	0,09	medium_impact	1,13	medium_impact	0,06	low_impact	-3,92	0,4	0,8	21,32	51,81	P	0,57	P	0,43	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8968	8968	A	T	MI.942	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	442	148	S	C	Agc/Tgc	-5,89	0	0	probably_damaging	1	deleterious	0	neutral	3,39	deleterious	-6,63	deleterious	-4,62	high_impact	4,59	damaging	0,45	damaging	0,04	deleterious	3,4	23	0,21	0,65	disease	0,97	disease	0,73	disease	0,68	disease	0,79	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,82	low_impact	-3,6	low_impact	-1,4	high_impact	2,84	0,55	0,9	50	8,78	N	0,38	N	0,99	polymorphism	0,74	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15261	15261	G	T	MI.9420	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	515	172	S	I	aGt/aTt	5,46	1	0	possibly_damaging	0,72	neutral	0,4	neutral	3,07	deleterious	-3,68	deleterious	-3,21	low_impact	1,72	neutral	0,95	neutral	0,57	deleterious	3,94	23,5	0,11	0,4	disease	0,56	disease	0,78	disease	0,52	disease	0,65	3	neutral	0,73	neutral	0,34	neutral	-3	deleterious	0,68	low_impact	-1,11	medium_impact	0,13	medium_impact	0,37	0,42	0,8	21,32	51,81	N	0,48	N	0,87	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15261	15261	G	C	MI.9421	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	515	172	S	T	aGt/aCt	5,46	1	0	benign	0,25	neutral	0,4	neutral	3,17	neutral	-0,6	neutral	-0,94	low_impact	1,07	neutral	0,94	neutral	0,63	deleterious	1,84	15,24	0,29	0,45	neutral	0,32	neutral	0,4	disease	0,51	neutral	0,43	1	neutral	0,52	deleterious	0,58	neutral	-6	neutral	0,28	medium_impact	-0,29	medium_impact	0,13	medium_impact	-0,22	0,52	0,8	21,32	51,81	N	0,56	P	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15263	15263	C	G	MI.9422	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	517	173	P	A	Ccc/Gcc	-0,04	0,91	0	benign	0	neutral	0,82	neutral	3,35	neutral	1,21	neutral	1,54	neutral_impact	-1,28	neutral	0,96	neutral	0,92	deleterious	0,06	3,23	0,14	0,4	neutral	0,15	neutral	0,12	neutral	0,29	neutral	0,24	5	neutral	0,17	deleterious	0,91	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,58	low_impact	-2,36	0,67	0,85	21,84	44	N	0,3	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15263	15263	C	A	MI.9423	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	517	173	P	T	Ccc/Acc	-0,04	0,91	0	benign	0,28	neutral	0,61	neutral	3,19	neutral	-0,85	neutral	-0,94	medium_impact	3,5	neutral	0,92	neutral	0,6	deleterious	3,61	23,2	0,13	0,4	neutral	0,5	neutral	0,42	disease	0,55	neutral	0,35	3	neutral	0,29	deleterious	0,67	neutral	-3	neutral	0,35	medium_impact	-0,35	medium_impact	0,33	medium_impact	1,98	0,67	0,85	21,84	44	N	0,28	N	0,44	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15263	15263	C	T	MI.9424	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	517	173	P	S	Ccc/Tcc	-0,04	0,91	0	benign	0,28	neutral	0,76	neutral	3,22	neutral	0,09	neutral	-0,31	medium_impact	2,07	neutral	0,92	neutral	0,61	deleterious	3,86	23,5	0,18	0,45	neutral	0,48	disease	0,52	disease	0,53	disease	0,58	2	neutral	0,19	deleterious	0,74	neutral	-3	neutral	0,38	medium_impact	-0,35	medium_impact	0,49	medium_impact	0,69	0,22	0,8	21,84	44	N	0,24	N	0,46	polymorphism	1	0,01	rs200455825	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15264	15264	C	T	MI.9425	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	518	173	P	L	cCc/cTc	4,77	1	0	possibly_damaging	0,5	neutral	0,39	neutral	3,22	neutral	-0,72	neutral	-1,98	medium_impact	2,9	neutral	0,93	neutral	0,53	deleterious	4,37	24,1	0,1	0,4	neutral	0,45	disease	0,61	disease	0,63	disease	0,69	4	neutral	0,59	neutral	0,45	NA	0	deleterious	0,52	medium_impact	-0,73	medium_impact	0,12	medium_impact	1,44	0,57	0,8	21,84	44	N	0,54	P	0,84	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15264	15264	C	G	MI.9426	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	518	173	P	R	cCc/cGc	4,77	1	0	possibly_damaging	0,84	neutral	0,55	neutral	3,22	neutral	-0,92	neutral	-1,77	medium_impact	3,5	neutral	0,93	neutral	0,48	deleterious	3,58	23,2	0,07	0,35	disease	0,65	disease	0,8	disease	0,79	disease	0,69	4	neutral	0,82	neutral	0,36	NA	0	deleterious	0,72	low_impact	-1,4	medium_impact	0,27	medium_impact	1,98	0,28	0,8	21,84	44	N	0,48	N	0,78	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15264	15264	C	A	MI.9427	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	518	173	P	H	cCc/cAc	4,77	1	0	probably_damaging	0,96	neutral	0,2	neutral	3,16	neutral	-1,66	neutral	-2,39	high_impact	4,04	neutral	0,88	neutral	0,46	deleterious	3,95	23,6	0,07	0,35	disease	0,76	disease	0,55	disease	0,76	disease	0,7	4	neutral	0,97	neutral	0,12	deleterious	2	deleterious	0,75	low_impact	-2,02	medium_impact	-0,1	high_impact	2,48	0,27	0,8	21,84	44	P	0,57	P	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15266	15266	A	T	MI.9428	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	520	174	T	S	Acc/Tcc	-14,5	0	0	probably_damaging	0,99	neutral	0,69	neutral	2,83	deleterious	-3,15	deleterious	-3,27	high_impact	4,74	neutral	0,84	neutral	0,47	deleterious	2,27	17,99	0,22	0,45	disease	0,64	disease	0,71	disease	0,68	disease	0,65	3	deleterious	0,99	neutral	0,35	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	0,41	high_impact	3,11	0,39	0,8	57,63	8,75	P	0,6	P	0,81	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15266	15266	A	C	MI.9429	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	520	174	T	P	Acc/Ccc	-14,5	0	0	probably_damaging	1	neutral	0,35	neutral	2,8	deleterious	-4,66	deleterious	-4,93	high_impact	5,29	neutral	0,92	neutral	0,33	deleterious	3,9	23,5	0,03	0,35	disease	0,83	disease	0,79	disease	0,85	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,08	high_impact	3,61	0,29	0,8	57,63	8,75	P	0,73	P	0,95	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8968	8968	A	G	MI.943	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	442	148	S	G	Agc/Ggc	-5,89	0	0	probably_damaging	0,98	deleterious	0,01	neutral	3,52	neutral	-2,12	deleterious	-3,67	medium_impact	3,15	damaging	0,52	damaging	0,14	deleterious	3,61	23,2	0,3	0,65	disease	0,6	disease	0,66	disease	0,66	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,75	low_impact	-2,36	medium_impact	-0,84	medium_impact	1,6	0,58	0,9	50	8,78	N	0,28	N	0,92	polymorphism	0,92	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15266	15266	A	G	MI.9430	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	520	174	T	A	Acc/Gcc	-14,5	0	0	probably_damaging	0,99	neutral	0,89	neutral	2,86	neutral	-2,12	deleterious	-4,09	high_impact	4,59	neutral	0,77	neutral	0,52	deleterious	2,35	18,47	0,13	0,4	disease	0,57	disease	0,68	disease	0,75	disease	0,69	4	deleterious	0,99	neutral	0,45	deleterious	2	deleterious	0,76	low_impact	-2,59	medium_impact	0,71	high_impact	2,97	0,28	0,8	57,63	8,75	N	0,43	N	0,59	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15267	15267	C	T	MI.9431	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	521	174	T	I	aCc/aTc	8,44	1	0	probably_damaging	1	neutral	0,48	neutral	2,94	neutral	-2,05	deleterious	-4,92	high_impact	5,08	neutral	0,84	neutral	0,46	deleterious	3,93	23,5	0,07	0,35	disease	0,57	disease	0,86	disease	0,76	disease	0,69	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,2	high_impact	3,42	0,5	0,8	57,63	8,75	P	0,75	P	0,83	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15267	15267	C	G	MI.9432	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	521	174	T	S	aCc/aGc	8,44	1	0	probably_damaging	0,99	neutral	0,69	neutral	2,83	deleterious	-3,15	deleterious	-3,27	high_impact	4,74	neutral	0,84	neutral	0,47	deleterious	1,94	15,85	0,22	0,45	disease	0,64	disease	0,71	disease	0,68	disease	0,65	3	deleterious	0,99	neutral	0,35	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	0,41	high_impact	3,11	0,39	0,8	57,63	8,75	P	0,7	P	0,81	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15267	15267	C	A	MI.9433	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	521	174	T	N	aCc/aAc	8,44	1	0	probably_damaging	1	neutral	0,54	neutral	2,81	deleterious	-4,54	deleterious	-4,09	high_impact	5,29	neutral	0,83	neutral	0,42	deleterious	3,49	23,1	0,21	0,45	disease	0,76	disease	0,85	disease	0,78	disease	0,68	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,26	high_impact	3,61	0,46	0,8	57,63	8,75	P	0,76	P	0,84	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15269	15269	C	A	MI.9434	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	523	175	L	I	Ctc/Atc	-8,99	0	0	probably_damaging	1	neutral	0,4	neutral	3,01	neutral	-2,64	neutral	-1,64	high_impact	4,13	neutral	0,88	damaging	0,06	deleterious	3,89	23,5	0,22	0,45	neutral	0,41	disease	0,68	disease	0,61	disease	0,65	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,13	high_impact	2,56	0,69	0,85	58,95	8,72	N	0,32	N	0,86	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15269	15269	C	G	MI.9435	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	523	175	L	V	Ctc/Gtc	-8,99	0	0	probably_damaging	0,99	neutral	0,51	neutral	2,91	neutral	-2,57	neutral	-2,46	high_impact	5,28	neutral	0,82	damaging	0,08	deleterious	3,05	22,4	0,17	0,45	disease	0,5	disease	0,69	disease	0,63	disease	0,65	3	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,77	low_impact	-2,59	medium_impact	0,23	high_impact	3,6	0,54	0,8	58,95	8,72	P	0,62	P	0,91	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15269	15269	C	T	MI.9436	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	523	175	L	F	Ctc/Ttc	-8,99	0	0	probably_damaging	1	neutral	0,73	neutral	2,97	deleterious	-3,07	deleterious	-3,27	high_impact	4,82	neutral	0,91	damaging	0,05	deleterious	3,88	23,5	0,09	0,35	disease	0,66	disease	0,77	disease	0,64	disease	0,66	3	deleterious	1	neutral	0,37	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,46	high_impact	3,18	0,61	0,8	58,95	8,72	P	0,6	P	0,97	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15270	15270	T	A	MI.9437	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	524	175	L	H	cTc/cAc	-0,73	0	0	probably_damaging	1	neutral	0,55	neutral	2,77	deleterious	-5,87	deleterious	-5,74	high_impact	5,62	neutral	0,88	damaging	0,06	deleterious	4,09	23,7	0,02	0,35	disease	0,84	disease	0,84	disease	0,72	disease	0,66	3	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,27	high_impact	3,91	0,28	0,8	58,95	8,72	P	0,6	P	0,95	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15270	15270	T	G	MI.9438	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	524	175	L	R	cTc/cGc	-0,73	0	0	probably_damaging	1	neutral	0,35	neutral	2,78	deleterious	-5,13	deleterious	-4,92	high_impact	5,62	neutral	0,84	damaging	0,03	deleterious	4,14	23,8	0,01	0,35	disease	0,76	disease	0,89	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,08	high_impact	3,91	0,11	0,8	58,95	8,72	P	0,7	P	0,99	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15270	15270	T	C	MI.9439	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	524	175	L	P	cTc/cCc	-0,73	0	0	probably_damaging	1	neutral	0,21	neutral	2,77	deleterious	-5,53	deleterious	-5,75	high_impact	5,62	neutral	0,87	damaging	0,03	deleterious	3,88	23,5	0,01	0,35	disease	0,85	disease	0,79	disease	0,74	disease	0,67	3	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,09	high_impact	3,91	0,17	0,8	58,95	8,72	P	0,6	P	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8968	8968	A	C	MI.944	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	442	148	S	R	Agc/Cgc	-5,89	0	0	probably_damaging	0,99	deleterious	0	neutral	3,45	deleterious	-3,22	deleterious	-4,57	high_impact	4,04	damaging	0,49	damaging	0,05	deleterious	3,85	23,4	0,19	0,65	disease	0,76	disease	0,88	disease	0,79	disease	0,77	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-2,65	low_impact	-1,4	high_impact	2,36	0,64	0,9	50	8,78	N	0,39	N	1	polymorphism	0,71	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15272	15272	A	C	MI.9440	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	526	176	T	P	Aca/Cca	-13,81	0	0	probably_damaging	1	neutral	0,18	neutral	3,13	neutral	-0,72	deleterious	-4,64	high_impact	4,67	neutral	0,84	neutral	0,3	deleterious	3,45	23	0,04	0,35	disease	0,66	disease	0,82	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,14	high_impact	3,05	0,29	0,8	21,84	16,54	N	0,54	P	0,95	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15272	15272	A	G	MI.9441	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	526	176	T	A	Aca/Gca	-13,81	0	0	probably_damaging	0,99	neutral	0,4	neutral	3,11	neutral	-1,06	deleterious	-3,73	high_impact	4,67	neutral	0,77	neutral	0,6	deleterious	3,07	22,4	0,16	0,45	neutral	0,4	disease	0,64	disease	0,56	disease	0,5	0	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,71	low_impact	-2,59	medium_impact	0,13	high_impact	3,05	0,42	0,8	21,84	16,54	N	0,54	P	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15272	15272	A	T	MI.9442	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	526	176	T	S	Aca/Tca	-13,81	0	0	probably_damaging	0,99	neutral	0,37	neutral	3,22	neutral	-0,56	deleterious	-2,92	medium_impact	3	neutral	0,89	neutral	0,5	deleterious	2,9	21,9	0,21	0,45	neutral	0,31	disease	0,72	neutral	0,32	neutral	0,35	3	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,72	low_impact	-2,59	medium_impact	0,1	medium_impact	1,53	0,58	0,8	21,84	16,54	N	0,34	N	0,81	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15273	15273	C	T	MI.9443	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	527	176	T	M	aCa/aTa	6,84	1	0	probably_damaging	1	neutral	0,15	neutral	3,04	deleterious	-3,4	deleterious	-4,51	high_impact	4,18	neutral	0,89	neutral	0,52	deleterious	4,02	23,6	0,08	0,35	disease	0,72	disease	0,8	neutral	0,49	disease	0,59	2	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,75	low_impact	-3,53	medium_impact	-0,19	high_impact	2,6	0,47	0,8	21,84	16,54	P	0,58	P	0,96	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15273	15273	C	A	MI.9444	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	527	176	T	K	aCa/aAa	6,84	1	0	probably_damaging	1	neutral	0,23	neutral	3,16	neutral	-0,7	deleterious	-4,58	medium_impact	3,25	neutral	0,84	neutral	0,35	deleterious	4,29	24	0,06	0,35	neutral	0,26	disease	0,87	disease	0,62	disease	0,67	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,75	low_impact	-3,53	medium_impact	-0,06	medium_impact	1,76	0,29	0,8	21,84	16,54	P	0,52	P	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15275	15275	C	G	MI.9445	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	529	177	R	G	Cga/Gga	-10,6	0	0	probably_damaging	1	neutral	0,35	neutral	2,55	deleterious	-7,05	deleterious	-5,74	high_impact	4,81	neutral	0,95	damaging	0,09	deleterious	4,21	23,9	0,03	0,35	disease	0,7	disease	0,76	disease	0,75	disease	0,69	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,08	high_impact	3,17	0,14	0,8	57,11	8,54	P	0,63	P	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15275	15275	C	T	MI.9446	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	529	177	R	W	Cga/Tga	-10,6	0	0	probably_damaging	1	neutral	0,18	neutral	2,54	deleterious	-8,82	deleterious	-6,57	high_impact	4,92	neutral	0,94	damaging	0,06	deleterious	5,21	25,6	0,05	0,35	disease	0,65	disease	0,83	disease	0,77	disease	0,7	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,14	high_impact	3,27	0,53	0,8	57,11	8,54	P	0,6	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15276	15276	G	A	MI.9447	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	530	177	R	Q	cGa/cAa	3,4	0,99	0	probably_damaging	1	neutral	0,29	neutral	2,57	deleterious	-5,61	deleterious	-3,28	high_impact	4,92	neutral	0,93	damaging	0,05	deleterious	4,54	24,3	0,13	0,4	disease	0,55	disease	0,78	disease	0,78	disease	0,69	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,01	high_impact	3,27	0,72	0,85	57,11	8,54	P	0,74	P	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15276	15276	G	C	MI.9448	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	530	177	R	P	cGa/cCa	3,4	0,99	0	probably_damaging	1	neutral	0,26	neutral	2,54	deleterious	-7,54	deleterious	-5,75	high_impact	5,27	neutral	0,93	damaging	0,04	deleterious	4,23	23,9	0,01	0,35	disease	0,77	disease	0,81	disease	0,85	disease	0,72	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	-0,02	high_impact	3,59	0,08	0,8	57,11	8,54	P	0,66	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15276	15276	G	T	MI.9449	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	530	177	R	L	cGa/cTa	3,4	0,99	0	probably_damaging	1	neutral	0,87	neutral	2,61	deleterious	-6,3	deleterious	-5,74	high_impact	4,72	neutral	0,94	damaging	0,06	deleterious	4,25	23,9	0,03	0,35	disease	0,63	disease	0,88	disease	0,75	disease	0,7	4	deleterious	1	neutral	0,44	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,67	high_impact	3,09	0,03	0,8	57,11	8,54	P	0,65	P	1	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8969	8969	G	C	MI.945	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	443	148	S	T	aGc/aCc	8,69	1	0	probably_damaging	0,98	deleterious	0	neutral	3,46	neutral	-2,98	deleterious	-2,72	high_impact	4,04	damaging	0,51	damaging	0,08	deleterious	3,46	23	0,22	0,65	disease	0,81	disease	0,65	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,36	low_impact	-1,4	high_impact	2,36	0,71	0,9	50	8,78	P	0,5	N	0,67	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15278	15278	T	G	MI.9450	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	532	178	F	V	Ttc/Gtc	-0,73	0,09	0	possibly_damaging	0,68	neutral	0,43	neutral	3,09	deleterious	-3,15	deleterious	-5,74	high_impact	4,53	neutral	0,88	damaging	0,11	deleterious	4,06	23,7	0,07	0,35	neutral	0,39	disease	0,84	disease	0,76	disease	0,7	4	neutral	0,69	neutral	0,38	deleterious	1	deleterious	0,59	low_impact	-1,04	medium_impact	0,16	high_impact	2,92	0,43	0,8	57,37	8,65	N	0,49	N	0,99	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15278	15278	T	A	MI.9451	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	532	178	F	I	Ttc/Atc	-0,73	0,09	0	benign	0,36	neutral	0,38	neutral	3,07	neutral	-2,53	deleterious	-4,92	high_impact	5,08	neutral	0,87	damaging	0,12	deleterious	4,28	24	0,11	0,4	neutral	0,5	disease	0,79	disease	0,75	disease	0,69	4	neutral	0,55	deleterious	0,51	neutral	-2	deleterious	0,56	medium_impact	-0,5	medium_impact	0,11	high_impact	3,42	0,5	0,8	57,37	8,65	P	0,63	P	0,97	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15278	15278	T	C	MI.9452	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	532	178	F	L	Ttc/Ctc	-0,73	0,09	0	benign	0,02	neutral	0,65	neutral	3,25	neutral	-0,76	deleterious	-4,92	high_impact	4,27	neutral	0,93	damaging	0,15	deleterious	3,79	23,4	0,14	0,4	neutral	0,4	disease	0,74	disease	0,68	disease	0,65	3	neutral	0,31	deleterious	0,82	neutral	-2	neutral	0,24	medium_impact	0,85	medium_impact	0,37	high_impact	2,68	0,68	0,85	57,37	8,65	N	0,31	N	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15279	15279	T	A	MI.9453	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	533	178	F	Y	tTc/tAc	7,3	1	0	possibly_damaging	0,72	neutral	0,8	neutral	2,91	deleterious	-4,57	neutral	-2,46	high_impact	5,62	neutral	0,88	damaging	0,11	deleterious	4,16	23,8	0,13	0,4	disease	0,7	disease	0,74	disease	0,72	disease	0,68	4	neutral	0,67	deleterious	0,54	deleterious	1	deleterious	0,73	low_impact	-1,11	medium_impact	0,55	high_impact	3,91	0,62	0,8	57,37	8,65	P	0,72	P	0,87	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15279	15279	T	G	MI.9454	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	533	178	F	C	tTc/tGc	7,3	1	0	probably_damaging	0,99	neutral	0,14	neutral	2,89	deleterious	-6,95	deleterious	-6,57	high_impact	5,62	neutral	0,87	damaging	0,09	deleterious	4,07	23,7	0,03	0,35	disease	0,83	disease	0,84	disease	0,76	disease	0,68	4	deleterious	0,99	neutral	0,08	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	-0,21	high_impact	3,91	0,24	0,8	57,37	8,65	P	0,67	P	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15279	15279	T	C	MI.9455	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	533	178	F	S	tTc/tCc	7,3	1	0	probably_damaging	0,94	neutral	0,42	neutral	2,92	deleterious	-6,42	deleterious	-6,55	high_impact	5,28	neutral	0,86	damaging	0,08	deleterious	4,24	23,9	0,02	0,35	disease	0,66	disease	0,82	disease	0,74	disease	0,7	4	neutral	0,94	neutral	0,24	deleterious	2	deleterious	0,81	low_impact	-1,85	medium_impact	0,15	high_impact	3,6	0,33	0,8	57,37	8,65	P	0,68	P	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15280	15280	C	G	MI.9456	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	534	178	F	L	ttC/ttG	5,69	1	0	benign	0,02	neutral	0,65	neutral	3,25	neutral	-0,76	deleterious	-4,92	high_impact	4,27	neutral	0,93	damaging	0,15	deleterious	4,06	23,7	0,14	0,4	neutral	0,4	disease	0,74	disease	0,68	disease	0,65	3	neutral	0,31	deleterious	0,82	neutral	-2	neutral	0,24	medium_impact	0,85	medium_impact	0,37	high_impact	2,68	0,68	0,85	57,37	8,65	N	0,52	P	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15280	15280	C	A	MI.9457	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	534	178	F	L	ttC/ttA	5,69	1	0	benign	0,02	neutral	0,65	neutral	3,25	neutral	-0,76	deleterious	-4,92	high_impact	4,27	neutral	0,93	damaging	0,15	deleterious	4,34	24	0,14	0,4	neutral	0,4	disease	0,74	disease	0,68	disease	0,65	3	neutral	0,31	deleterious	0,82	neutral	-2	neutral	0,24	medium_impact	0,85	medium_impact	0,37	high_impact	2,68	0,68	0,85	57,37	8,65	N	0,52	P	0,92	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15281	15281	T	G	MI.9458	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	535	179	F	V	Ttt/Gtt	-0,96	0,02	0	probably_damaging	1	neutral	0,18	neutral	3,02	deleterious	-3,42	deleterious	-5,7	high_impact	5,53	neutral	0,88	damaging	0,12	deleterious	3,85	23,4	0,06	0,35	disease	0,81	disease	0,87	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,14	high_impact	3,83	0,33	0,8	56,05	8,81	P	0,64	P	0,99	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15281	15281	T	A	MI.9459	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	535	179	F	I	Ttt/Att	-0,96	0,02	0	probably_damaging	1	neutral	0,1	neutral	3,01	deleterious	-3,84	deleterious	-4,89	high_impact	5,53	neutral	0,87	damaging	0,12	deleterious	4,14	23,8	0,1	0,4	disease	0,81	disease	0,83	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,3	high_impact	3,83	0,53	0,8	56,05	8,81	P	0,64	P	0,97	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8969	8969	G	A	MI.946	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	443	148	S	N	aGc/aAc	8,69	1	0	probably_damaging	0,98	deleterious	0	neutral	3,46	neutral	-2,96	deleterious	-2,76	high_impact	4,59	damaging	0,47	damaging	0,07	deleterious	3,63	23,2	0,45	0,65	disease	0,8	disease	0,71	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,81	low_impact	-2,36	low_impact	-1,4	high_impact	2,84	0,44	0,9	50	8,78	P	0,57	P	0,88	disease_causing_automatic	1	0,33	rs794726857	Pathogenic	Myopathy,_lactic_acidosis,_and_sideroblastic_anemia_3	RCV000171545.4	MedGen:OMIM	.	.	.	.	G8969A	Mitochondrial myopathy,lactic acidosis and sideroblastic anemia(MLASA)	-	+	Reported	1
chrM	15281	15281	T	C	MI.9460	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	535	179	F	L	Ttt/Ctt	-0,96	0,02	0	probably_damaging	1	neutral	0,59	neutral	3,25	neutral	-1,99	deleterious	-4,89	high_impact	4,49	neutral	0,92	damaging	0,1	deleterious	3,6	23,2	0,13	0,4	disease	0,67	disease	0,77	disease	0,58	disease	0,57	1	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,31	high_impact	2,88	0,59	0,8	56,05	8,81	N	0,37	N	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15282	15282	T	C	MI.9461	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	536	179	F	S	tTt/tCt	5,69	1	0	probably_damaging	1	neutral	0,12	neutral	2,95	deleterious	-4,68	deleterious	-6,52	high_impact	4,97	neutral	0,91	damaging	0,1	deleterious	4,18	23,8	0,02	0,35	disease	0,88	disease	0,84	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,25	high_impact	3,32	0,4	0,8	56,05	8,81	P	0,7	P	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15282	15282	T	G	MI.9462	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	536	179	F	C	tTt/tGt	5,69	1	0	probably_damaging	1	deleterious	0,03	neutral	2,93	deleterious	-6,1	deleterious	-6,53	high_impact	5,17	neutral	0,87	damaging	0,1	deleterious	4,04	23,7	0,03	0,35	disease	0,95	disease	0,86	disease	0,61	disease	0,66	3	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,84	low_impact	-3,53	medium_impact	-0,6	high_impact	3,5	0,3	0,8	56,05	8,81	P	0,63	P	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15282	15282	T	A	MI.9463	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	536	179	F	Y	tTt/tAt	5,69	1	0	probably_damaging	1	neutral	0,19	neutral	3,2	neutral	-0,26	neutral	-2,41	medium_impact	2,73	neutral	0,88	damaging	0,12	deleterious	3,91	23,5	0,15	0,4	neutral	0,35	disease	0,76	neutral	0,5	neutral	0,41	2	deleterious	1	neutral	0,1	deleterious	1	deleterious	0,76	low_impact	-3,53	medium_impact	-0,12	medium_impact	1,29	0,58	0,8	56,05	8,81	N	0,49	N	0,87	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15283	15283	T	A	MI.9464	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	537	179	F	L	ttT/ttA	5,69	1	0	probably_damaging	1	neutral	0,59	neutral	3,25	neutral	-1,99	deleterious	-4,89	high_impact	4,49	neutral	0,92	damaging	0,1	deleterious	4,09	23,7	0,13	0,4	disease	0,67	disease	0,77	disease	0,58	disease	0,57	1	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,31	high_impact	2,88	0,59	0,8	56,05	8,81	P	0,56	P	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15283	15283	T	G	MI.9465	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	537	179	F	L	ttT/ttG	5,69	1	0	probably_damaging	1	neutral	0,59	neutral	3,25	neutral	-1,99	deleterious	-4,89	high_impact	4,49	neutral	0,92	damaging	0,1	deleterious	3,96	23,6	0,13	0,4	disease	0,67	disease	0,77	disease	0,58	disease	0,57	1	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,31	high_impact	2,88	0,59	0,8	56,05	8,81	P	0,55	P	0,92	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15284	15284	A	C	MI.9466	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	538	180	T	P	Acc/Ccc	-5,55	0	0	probably_damaging	1	neutral	0,17	neutral	3,09	neutral	-2,59	neutral	-2,27	high_impact	3,76	neutral	0,88	damaging	0,21	deleterious	3,34	22,9	0,06	0,35	disease	0,63	disease	0,88	disease	0,73	disease	0,76	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,15	high_impact	2,22	0,48	0,8	23,42	45,05	N	0,38	N	0,67	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15284	15284	A	T	MI.9467	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	538	180	T	S	Acc/Tcc	-5,55	0	0	probably_damaging	1	neutral	0,2	neutral	3,16	neutral	0,76	neutral	-0,64	neutral_impact	0,56	neutral	0,86	damaging	0,25	deleterious	2,96	22,1	0,16	0,45	neutral	0,17	disease	0,57	neutral	0,36	neutral	0,23	5	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,67	low_impact	-3,53	medium_impact	-0,1	medium_impact	-0,69	0,61	0,8	23,42	45,05	N	0,3	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15284	15284	A	G	MI.9468	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	538	180	T	A	Acc/Gcc	-5,55	0	0	probably_damaging	1	neutral	0,55	neutral	3,36	neutral	1,31	neutral	0,6	neutral_impact	0	neutral	0,95	neutral	0,92	deleterious	0,39	6,5	0,15	0,4	neutral	0,15	neutral	0,06	neutral	0,32	neutral	0,19	6	deleterious	1	neutral	0,28	neutral	-2	deleterious	0,63	low_impact	-3,53	medium_impact	0,27	low_impact	-1,19	0,42	0,8	23,42	45,05	N	0,37	N	0,01	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15285	15285	C	T	MI.9469	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	539	180	T	I	aCc/aTc	2,94	0,95	0	probably_damaging	1	neutral	0,36	neutral	3,19	neutral	0,57	neutral	-2,12	medium_impact	3,28	neutral	0,86	damaging	0,26	deleterious	3,84	23,4	0,08	0,35	neutral	0,43	disease	0,81	disease	0,56	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	1	deleterious	0,74	low_impact	-3,53	medium_impact	0,09	medium_impact	1,79	0,62	0,8	23,42	45,05	N	0,38	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8969	8969	G	T	MI.947	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	443	148	S	I	aGc/aTc	8,69	1	0	probably_damaging	0,99	deleterious	0	neutral	3,4	deleterious	-6,11	deleterious	-5,48	high_impact	4,59	damaging	0,49	damaging	0,06	deleterious	4,16	23,8	0,2	0,65	disease	0,92	disease	0,9	disease	0,7	disease	0,79	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,86	low_impact	-2,65	low_impact	-1,4	high_impact	2,84	0,68	0,9	50	8,78	P	0,48	N	1	disease_causing	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15285	15285	C	G	MI.9470	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	539	180	T	S	aCc/aGc	2,94	0,95	0	probably_damaging	1	neutral	0,2	neutral	3,16	neutral	0,76	neutral	-0,64	neutral_impact	0,56	neutral	0,86	damaging	0,25	deleterious	3,19	22,7	0,16	0,45	neutral	0,17	disease	0,57	neutral	0,36	neutral	0,23	5	deleterious	1	neutral	0,1	neutral	-2	deleterious	0,67	low_impact	-3,53	medium_impact	-0,1	medium_impact	-0,69	0,61	0,8	23,42	45,05	N	0,34	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15285	15285	C	A	MI.9471	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	539	180	T	N	aCc/aAc	2,94	0,95	0	probably_damaging	1	neutral	0,19	neutral	3,08	neutral	-2,35	neutral	-2,48	high_impact	4,57	neutral	0,86	damaging	0,26	deleterious	3,47	23	0,18	0,45	disease	0,51	disease	0,83	disease	0,62	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	-0,12	high_impact	2,96	0,65	0,8	23,42	45,05	N	0,51	P	0,6	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15287	15287	T	G	MI.9472	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	541	181	F	V	Ttt/Gtt	-4,86	0	0,01	benign	0,28	neutral	0,26	neutral	3,19	neutral	0,19	deleterious	-3,89	high_impact	3,84	neutral	0,95	neutral	0,49	deleterious	3,79	23,4	0,07	0,35	neutral	0,31	disease	0,86	disease	0,7	disease	0,72	4	neutral	0,69	deleterious	0,49	neutral	-2	neutral	0,27	medium_impact	-0,35	medium_impact	-0,02	high_impact	2,29	0,39	0,8	20,79	34,54	N	0,44	N	0,78	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15287	15287	T	C	MI.9473	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	541	181	F	L	Ttt/Ctt	-4,86	0	0,01	benign	0	neutral	0,65	neutral	3,45	neutral	2,72	deleterious	-2,69	low_impact	0,91	neutral	0,96	neutral	0,78	neutral	1,05	10,92	0,19	0,45	neutral	0,16	disease	0,56	disease	0,51	neutral	0,23	5	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	0,37	medium_impact	-0,37	0,51	0,8	20,79	34,54	N	0,3	N	0,08	polymorphism	1	0,04	rs527236044	Likely pathogenic	Familial_cancer_of_breast	RCV000128805.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	12,93	T15287C	Possible DEAF helper mut.	-	+	Further studies needed	1
chrM	15287	15287	T	A	MI.9474	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	541	181	F	I	Ttt/Att	-4,86	0	0,01	benign	0,1	neutral	0,37	neutral	3,18	neutral	0,33	deleterious	-3,07	medium_impact	2,72	neutral	0,94	neutral	0,48	deleterious	3,94	23,5	0,1	0,4	neutral	0,35	disease	0,8	disease	0,54	neutral	0,27	5	neutral	0,58	deleterious	0,64	neutral	-3	neutral	0,24	medium_impact	0,16	medium_impact	0,1	medium_impact	1,28	0,47	0,8	20,79	34,54	N	0,3	N	0,68	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15288	15288	T	A	MI.9475	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	542	181	F	Y	tTt/tAt	0,64	0,47	0	possibly_damaging	0,44	neutral	0,53	neutral	3,1	neutral	-1,3	neutral	-2,01	high_impact	5,19	neutral	0,98	neutral	0,47	deleterious	2,48	19,33	0,14	0,4	disease	0,55	disease	0,78	disease	0,7	disease	0,7	4	neutral	0,44	deleterious	0,55	deleterious	1	neutral	0,42	medium_impact	-0,63	medium_impact	0,25	high_impact	3,52	0,5	0,8	20,79	34,54	P	0,55	P	0,71	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15288	15288	T	G	MI.9476	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	542	181	F	C	tTt/tGt	0,64	0,47	0	probably_damaging	0,91	neutral	0,1	neutral	3,07	neutral	-2,71	deleterious	-4,98	high_impact	4,84	neutral	0,94	neutral	0,39	deleterious	4,06	23,7	0,02	0,35	disease	0,69	disease	0,86	disease	0,73	disease	0,72	4	neutral	0,97	neutral	0,1	deleterious	2	deleterious	0,74	low_impact	-1,67	medium_impact	-0,3	high_impact	3,2	0,32	0,8	20,79	34,54	P	0,63	P	0,79	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15288	15288	T	C	MI.9477	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	542	181	F	S	tTt/tCt	0,64	0,47	0	benign	0,03	neutral	0,23	neutral	3,09	neutral	-1,18	deleterious	-5,2	high_impact	4,84	neutral	0,93	neutral	0,47	deleterious	3,94	23,5	0,02	0,35	neutral	0,37	disease	0,82	disease	0,7	disease	0,69	4	neutral	0,76	deleterious	0,6	neutral	-2	neutral	0,23	medium_impact	0,68	medium_impact	-0,06	high_impact	3,2	0,46	0,8	20,79	34,54	N	0,54	P	0,91	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15289	15289	T	G	MI.9478	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	543	181	F	L	ttT/ttG	7,3	0,98	0,01	benign	0	neutral	0,65	neutral	3,45	neutral	2,72	deleterious	-2,69	low_impact	0,91	neutral	0,96	neutral	0,78	neutral	1,41	12,84	0,19	0,45	neutral	0,16	disease	0,56	disease	0,51	neutral	0,23	5	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	0,37	medium_impact	-0,37	0,51	0,8	20,79	34,54	N	0,51	P	0,08	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15289	15289	T	A	MI.9479	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	543	181	F	L	ttT/ttA	7,3	0,98	0,01	benign	0	neutral	0,65	neutral	3,45	neutral	2,72	deleterious	-2,69	low_impact	0,91	neutral	0,96	neutral	0,78	neutral	1,49	13,24	0,19	0,45	neutral	0,16	disease	0,56	disease	0,51	neutral	0,23	5	neutral	0,34	deleterious	0,83	neutral	-6	neutral	0,14	high_impact	2,07	medium_impact	0,37	medium_impact	-0,37	0,51	0,8	20,79	34,54	P	0,51	P	0,08	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8971	8971	C	G	MI.948	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	445	149	L	V	Cta/Gta	-0,57	0	0	probably_damaging	0,99	neutral	0,38	neutral	4,2	neutral	-1,06	deleterious	-2,73	medium_impact	2,1	neutral	0,71	neutral	0,44	deleterious	3,44	23	0,48	0,65	disease	0,62	disease	0,64	neutral	0,48	neutral	0,46	1	deleterious	0,99	neutral	0,2	deleterious	1	deleterious	0,79	low_impact	-2,65	medium_impact	0,17	medium_impact	0,7	0,63	0,9	49,56	8,82	N	0,27	N	0,87	disease_causing	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15290	15290	C	G	MI.9480	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	544	182	H	D	Cac/Gac	-6,47	0	0	probably_damaging	1	neutral	0,07	neutral	1,72	deleterious	-9,72	deleterious	-7,42	high_impact	5,63	neutral	0,92	neutral	0,36	deleterious	3,69	23,3	0,05	0,35	disease	0,74	disease	0,83	disease	0,83	disease	0,72	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,39	high_impact	3,92	0,37	0,8	56,58	8,81	P	0,6	P	0,98	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15290	15290	C	A	MI.9481	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	544	182	H	N	Cac/Aac	-6,47	0	0	probably_damaging	1	neutral	0,15	neutral	1,72	deleterious	-8,79	deleterious	-5,77	high_impact	4,95	neutral	0,92	neutral	0,43	deleterious	3,53	23,1	0,19	0,45	disease	0,71	disease	0,84	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,19	high_impact	3,3	0,42	0,8	56,58	8,81	P	0,64	P	0,97	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15290	15290	C	T	MI.9482	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	544	182	H	Y	Cac/Tac	-6,47	0	0	probably_damaging	1	neutral	0,42	neutral	1,72	deleterious	-8,53	deleterious	-4,95	high_impact	5,29	neutral	0,93	neutral	0,39	deleterious	3,36	22,9	0,11	0,4	disease	0,63	disease	0,87	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,15	high_impact	3,61	0,36	0,8	56,58	8,81	P	0,72	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15291	15291	A	T	MI.9483	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	545	182	H	L	cAc/cTc	4,31	0,99	0	probably_damaging	1	neutral	0,67	neutral	1,72	deleterious	-9,35	deleterious	-9,07	high_impact	5,08	neutral	0,94	neutral	0,38	deleterious	3,48	23,1	0,03	0,35	neutral	0,44	disease	0,9	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,39	high_impact	3,42	0,25	0,8	56,58	8,81	P	0,63	P	0,92	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15291	15291	A	C	MI.9484	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	545	182	H	P	cAc/cCc	4,31	0,99	0	probably_damaging	1	neutral	0,18	neutral	1,72	deleterious	-9,92	deleterious	-8,24	high_impact	5,08	neutral	0,94	damaging	0,28	deleterious	3,03	22,3	0,03	0,35	disease	0,83	disease	0,87	disease	0,83	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,14	high_impact	3,42	0,29	0,8	56,58	8,81	P	0,63	P	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15291	15291	A	G	MI.9485	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	545	182	H	R	cAc/cGc	4,31	0,99	0	probably_damaging	1	neutral	0,19	neutral	1,74	deleterious	-9,36	deleterious	-6,59	high_impact	5,08	neutral	0,94	neutral	0,34	deleterious	2,67	20,6	0,08	0,35	disease	0,56	disease	0,9	disease	0,8	disease	0,75	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,12	high_impact	3,42	0,36	0,8	56,58	8,81	P	0,64	P	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15292	15292	C	A	MI.9486	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	546	182	H	Q	caC/caA	8,44	1	0,01	probably_damaging	1	neutral	0,1	neutral	1,72	deleterious	-9,43	deleterious	-6,59	high_impact	5,08	neutral	0,94	neutral	0,36	deleterious	3,55	23,1	0,12	0,4	disease	0,65	disease	0,81	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	-0,3	high_impact	3,42	0,42	0,8	56,58	8,81	P	0,65	P	0,94	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15292	15292	C	G	MI.9487	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	546	182	H	Q	caC/caG	8,44	1	0,01	probably_damaging	1	neutral	0,1	neutral	1,72	deleterious	-9,43	deleterious	-6,59	high_impact	5,08	neutral	0,94	neutral	0,36	deleterious	3,28	22,8	0,12	0,4	disease	0,65	disease	0,81	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,05	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	-0,3	high_impact	3,42	0,42	0,8	56,58	8,81	P	0,64	P	0,94	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15293	15293	T	G	MI.9488	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	547	183	F	V	Ttc/Gtc	-0,73	0,05	0	probably_damaging	1	neutral	0,35	neutral	3,4	neutral	1,45	deleterious	-5,75	high_impact	4,11	neutral	0,95	damaging	0,11	deleterious	4,11	23,7	0,06	0,35	neutral	0,45	disease	0,88	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	0,08	high_impact	2,54	0,46	0,8	57,37	8,61	N	0,38	N	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15293	15293	T	C	MI.9489	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	547	183	F	L	Ttc/Ctc	-0,73	0,05	0	probably_damaging	1	neutral	0,79	neutral	3,15	neutral	-0,29	deleterious	-4,93	high_impact	4,58	neutral	0,96	damaging	0,1	deleterious	3,88	23,5	0,11	0,4	neutral	0,34	disease	0,84	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,4	deleterious	2	deleterious	0,74	low_impact	-3,53	medium_impact	0,53	high_impact	2,97	0,59	0,8	57,37	8,61	N	0,36	N	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8971	8971	C	A	MI.949	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	445	149	L	M	Cta/Ata	-0,57	0	0	probably_damaging	1	neutral	0,15	neutral	4,18	neutral	-2,43	neutral	-1,82	medium_impact	2,8	neutral	0,8	neutral	0,5	deleterious	3,75	23,3	0,38	0,65	disease	0,76	disease	0,54	neutral	0,36	neutral	0,48	0	deleterious	1	neutral	0,08	deleterious	1	deleterious	0,78	low_impact	-3,6	medium_impact	-0,13	medium_impact	1,3	0,58	0,9	49,56	8,82	N	0,36	N	0,96	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15293	15293	T	A	MI.9490	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	547	183	F	I	Ttc/Atc	-0,73	0,05	0	probably_damaging	1	neutral	0,29	neutral	3,58	neutral	2	deleterious	-4,93	high_impact	4,75	neutral	0,94	damaging	0,12	deleterious	4,43	24,2	0,09	0,35	neutral	0,34	disease	0,87	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,01	high_impact	3,12	0,63	0,8	57,37	8,61	P	0,62	P	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15294	15294	T	G	MI.9491	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	548	183	F	C	tTc/tGc	5,69	1	0	probably_damaging	1	neutral	0,08	neutral	3,05	neutral	-2,55	deleterious	-6,58	high_impact	4,86	neutral	0,94	damaging	0,09	deleterious	4,09	23,7	0,03	0,35	disease	0,79	disease	0,88	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	-0,35	high_impact	3,22	0,28	0,8	57,37	8,61	P	0,7	P	0,99	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15294	15294	T	A	MI.9492	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	548	183	F	Y	tTc/tAc	5,69	1	0	probably_damaging	1	neutral	0,6	neutral	3,07	neutral	-1,6	neutral	-2,45	medium_impact	2,54	neutral	0,94	damaging	0,13	deleterious	3,94	23,5	0,13	0,4	neutral	0,24	disease	0,81	disease	0,52	disease	0,55	1	deleterious	1	neutral	0,3	deleterious	1	deleterious	0,73	low_impact	-3,53	medium_impact	0,32	medium_impact	1,11	0,63	0,8	57,37	8,61	N	0,45	N	0,87	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15294	15294	T	C	MI.9493	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	548	183	F	S	tTc/tCc	5,69	1	0	probably_damaging	1	neutral	0,31	neutral	3,05	neutral	-2,3	deleterious	-6,57	high_impact	5,2	neutral	0,93	damaging	0,08	deleterious	4,2	23,9	0,02	0,35	neutral	0,43	disease	0,85	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	0,03	high_impact	3,53	0,52	0,8	57,37	8,61	P	0,68	P	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15295	15295	C	G	MI.9494	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	549	183	F	L	ttC/ttG	5,69	1	0	probably_damaging	1	neutral	0,79	neutral	3,15	neutral	-0,29	deleterious	-4,93	high_impact	4,58	neutral	0,96	damaging	0,1	deleterious	4,05	23,7	0,11	0,4	neutral	0,34	disease	0,84	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,4	deleterious	2	deleterious	0,74	low_impact	-3,53	medium_impact	0,53	high_impact	2,97	0,59	0,8	57,37	8,61	P	0,51	P	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15295	15295	C	A	MI.9495	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	549	183	F	L	ttC/ttA	5,69	1	0	probably_damaging	1	neutral	0,79	neutral	3,15	neutral	-0,29	deleterious	-4,93	high_impact	4,58	neutral	0,96	damaging	0,1	deleterious	4,41	24,1	0,11	0,4	neutral	0,34	disease	0,84	disease	0,6	disease	0,69	4	deleterious	1	neutral	0,4	deleterious	2	deleterious	0,74	low_impact	-3,53	medium_impact	0,53	high_impact	2,97	0,59	0,8	57,37	8,61	P	0,52	P	0,92	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15296	15296	A	C	MI.9496	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	550	184	I	L	Atc/Ctc	-2,8	0	0	benign	0,12	neutral	0,95	neutral	3,16	neutral	0,66	neutral	0,51	neutral_impact	-0,22	neutral	0,96	neutral	0,82	neutral	-0,13	1,54	0,2	0,45	neutral	0,17	neutral	0,15	neutral	0,21	neutral	0,25	5	neutral	0,04	deleterious	0,92	neutral	-6	neutral	0,11	medium_impact	0,08	medium_impact	0,92	low_impact	-1,39	0,49	0,8	20,53	27,46	N	0,3	N	0,63	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15296	15296	A	T	MI.9497	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	550	184	I	F	Atc/Ttc	-2,8	0	0	possibly_damaging	0,73	neutral	1	neutral	2,85	neutral	-2,2	neutral	-2,12	medium_impact	2,76	neutral	0,94	neutral	0,44	deleterious	3,53	23,1	0,12	0,4	disease	0,6	disease	0,83	neutral	0,5	neutral	0,47	1	neutral	0,73	deleterious	0,64	NA	0	deleterious	0,66	low_impact	-1,13	high_impact	1,85	medium_impact	1,31	0,42	0,8	20,53	27,46	N	0,17	N	0,86	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15296	15296	A	G	MI.9498	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	550	184	I	V	Atc/Gtc	-2,8	0	0	benign	0,13	neutral	0,3	neutral	3,09	neutral	0,04	neutral	-0,71	medium_impact	2,1	neutral	0,98	neutral	0,89	deleterious	0,12	3,8	0,3	0,45	neutral	0,25	neutral	0,47	neutral	0,38	neutral	0,34	3	neutral	0,65	deleterious	0,59	neutral	-3	neutral	0,15	medium_impact	0,04	medium_impact	0,02	medium_impact	0,71	0,34	0,8	20,53	27,46	N	0,4	N	0,5	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15297	15297	T	G	MI.9499	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	551	184	I	S	aTc/aGc	0,64	0,14	0	possibly_damaging	0,87	neutral	0,21	neutral	2,84	deleterious	-3,1	deleterious	-3,57	high_impact	3,73	neutral	0,94	neutral	0,43	deleterious	4,2	23,9	0,04	0,35	disease	0,61	disease	0,81	disease	0,58	disease	0,71	4	neutral	0,92	neutral	0,17	deleterious	1	deleterious	0,72	low_impact	-1,5	medium_impact	-0,09	high_impact	2,19	0,2	0,8	20,53	27,46	N	0,46	N	0,95	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8569	8569	C	A	MI.95	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	43	15	L	M	Cta/Ata	-2,88	0	0	probably_damaging	1	neutral	0,34	neutral	4,46	neutral	-2,05	neutral	-0,36	low_impact	1,09	neutral	0,9	neutral	0,86	neutral	1,72	14,51	0,38	0,65	neutral	0,47	neutral	0,15	neutral	0,4	neutral	0,28	4	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,68	low_impact	-3,6	medium_impact	0,13	medium_impact	-0,16	0,77	0,9	11,5	26,27	N	0,48	N	0,11	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8972	8972	T	G	MI.950	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	446	149	L	R	cTa/cGa	-0,1	0	0	probably_damaging	1	neutral	0,24	neutral	4,23	deleterious	-3,52	deleterious	-5,48	medium_impact	3,49	neutral	0,75	neutral	0,31	deleterious	4,24	23,9	0,24	0,65	disease	0,6	disease	0,9	disease	0,63	disease	0,72	4	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,86	low_impact	-3,6	medium_impact	0,01	medium_impact	1,89	0,53	0,9	49,56	8,82	N	0,33	N	0,99	disease_causing	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15297	15297	T	C	MI.9500	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	551	184	I	T	aTc/aCc	0,64	0,14	0	possibly_damaging	0,83	neutral	0,24	neutral	2,85	neutral	-2,5	deleterious	-2,75	medium_impact	2,65	neutral	0,97	neutral	0,68	deleterious	3,19	22,7	0,08	0,35	neutral	0,42	disease	0,59	disease	0,53	neutral	0,49	0	neutral	0,88	neutral	0,21	NA	0	deleterious	0,61	low_impact	-1,37	medium_impact	-0,05	medium_impact	1,21	0,28	0,8	20,53	27,46	N	0,46	N	0,95	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15297	15297	T	A	MI.9501	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	551	184	I	N	aTc/aAc	0,64	0,14	0	probably_damaging	0,96	neutral	0,06	neutral	2,82	deleterious	-4,35	deleterious	-4,44	high_impact	4,7	neutral	0,92	neutral	0,45	deleterious	4,37	24,1	0,08	0,35	disease	0,75	disease	0,88	disease	0,61	disease	0,72	4	deleterious	0,99	neutral	0,05	deleterious	2	deleterious	0,8	low_impact	-2,02	medium_impact	-0,43	high_impact	3,07	0,27	0,8	20,53	27,46	P	0,6	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15298	15298	C	A	MI.9502	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	552	184	I	M	atC/atA	4,54	0,7	0	benign	0,2	neutral	0,12	neutral	2,85	neutral	-2,61	neutral	-0,74	medium_impact	2,28	neutral	0,91	neutral	0,54	deleterious	3,64	23,2	0,2	0,45	disease	0,59	disease	0,57	neutral	0,35	neutral	0,21	6	neutral	0,86	neutral	0,46	neutral	-3	neutral	0,22	medium_impact	-0,17	medium_impact	-0,25	medium_impact	0,88	0,47	0,8	20,53	27,46	N	0,4	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15298	15298	C	G	MI.9503	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	552	184	I	M	atC/atG	4,54	0,7	0	benign	0,2	neutral	0,12	neutral	2,85	neutral	-2,61	neutral	-0,74	medium_impact	2,28	neutral	0,91	neutral	0,54	deleterious	3,21	22,7	0,2	0,45	disease	0,59	disease	0,57	neutral	0,35	neutral	0,21	6	neutral	0,86	neutral	0,46	neutral	-3	neutral	0,22	medium_impact	-0,17	medium_impact	-0,25	medium_impact	0,88	0,47	0,8	20,53	27,46	N	0,39	N	0,25	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15299	15299	T	G	MI.9504	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	553	185	L	V	Ttg/Gtg	-6,47	0	0,01	probably_damaging	0,99	neutral	0,21	neutral	2,85	neutral	-2,61	neutral	-2,06	medium_impact	3,27	neutral	0,94	neutral	0,47	deleterious	3,02	22,3	0,23	0,45	neutral	0,38	disease	0,7	disease	0,53	disease	0,57	1	deleterious	0,99	neutral	0,11	deleterious	1	deleterious	0,73	low_impact	-2,59	medium_impact	-0,09	medium_impact	1,78	0,44	0,8	57,89	8,82	N	0,4	N	0,91	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15299	15299	T	A	MI.9505	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	553	185	L	M	Ttg/Atg	-6,47	0	0,01	probably_damaging	1	neutral	0,12	neutral	2,68	deleterious	-3,6	neutral	-1,29	medium_impact	2,83	neutral	0,94	neutral	0,54	deleterious	3,47	23	0,22	0,45	disease	0,53	disease	0,59	neutral	0,4	neutral	0,44	1	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,72	low_impact	-3,53	medium_impact	-0,25	medium_impact	1,38	0,5	0,8	57,89	8,82	N	0,42	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15300	15300	T	G	MI.9506	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	554	185	L	W	tTg/tGg	-0,5	0	0	probably_damaging	1	deleterious	0,03	neutral	2,61	deleterious	-7,2	deleterious	-3,81	high_impact	5,02	neutral	0,94	neutral	0,35	deleterious	3,76	23,4	0,04	0,35	disease	0,87	disease	0,82	disease	0,64	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,83	low_impact	-3,53	medium_impact	-0,6	high_impact	3,36	0,22	0,8	57,89	8,82	P	0,68	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15300	15300	T	C	MI.9507	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	554	185	L	S	tTg/tCg	-0,5	0	0	probably_damaging	1	neutral	0,16	neutral	2,65	deleterious	-4,93	deleterious	-4,13	high_impact	4,82	neutral	0,88	neutral	0,47	deleterious	3,7	23,3	0,02	0,35	neutral	0,44	disease	0,79	disease	0,62	disease	0,65	3	deleterious	1	neutral	0,08	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	-0,17	high_impact	3,18	0,46	0,8	57,89	8,82	P	0,55	P	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15301	15301	G	T	MI.9508	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	555	185	L	F	ttG/ttT	5,69	0,87	0,71	probably_damaging	1	neutral	0,9	neutral	2,72	deleterious	-3,76	neutral	-1,79	medium_impact	1,96	neutral	0,94	neutral	0,43	deleterious	3,49	23,1	0,16	0,45	disease	0,62	neutral	0,49	neutral	0,42	neutral	0,49	0	deleterious	1	neutral	0,45	deleterious	1	deleterious	0,76	low_impact	-3,53	medium_impact	0,74	medium_impact	0,59	0,44	0,8	57,89	8,82	N	0,38	N	0,97	polymorphism	1	0,04	rs193302991	Likely pathogenic	Familial_cancer_of_breast	RCV000128806.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	15301	15301	G	C	MI.9509	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	555	185	L	F	ttG/ttC	5,69	0,87	0,71	probably_damaging	1	neutral	0,9	neutral	2,72	deleterious	-3,76	neutral	-1,79	medium_impact	1,96	neutral	0,94	neutral	0,43	deleterious	3,33	22,9	0,16	0,45	disease	0,62	neutral	0,49	neutral	0,42	neutral	0,49	0	deleterious	1	neutral	0,45	deleterious	1	deleterious	0,76	low_impact	-3,53	medium_impact	0,74	medium_impact	0,59	0,44	0,8	57,89	8,82	N	0,37	N	0,97	polymorphism	1	0,04	rs193302991	Likely pathogenic	Familial_cancer_of_breast	RCV000128806.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	8972	8972	T	A	MI.951	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	446	149	L	Q	cTa/cAa	-0,1	0	0	probably_damaging	1	neutral	0,23	neutral	4,24	neutral	-2,82	deleterious	-5,47	medium_impact	2,27	neutral	0,87	neutral	0,42	deleterious	4,11	23,7	0,24	0,65	disease	0,57	disease	0,76	neutral	0,5	disease	0,52	0	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	-0,01	medium_impact	0,85	0,58	0,9	49,56	8,82	N	0,34	N	0,98	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15302	15302	C	G	MI.9510	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	556	186	P	A	Ccc/Gcc	-14,27	0	0	probably_damaging	1	neutral	0,44	neutral	2,62	deleterious	-4,83	deleterious	-6,61	high_impact	4,53	neutral	0,94	damaging	0,15	deleterious	2,84	21,6	0,12	0,4	disease	0,57	disease	0,71	disease	0,69	disease	0,67	3	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,75	low_impact	-3,53	medium_impact	0,17	high_impact	2,92	0,68	0,85	58,95	8,72	N	0,4	N	0,84	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15302	15302	C	A	MI.9511	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	556	186	P	T	Ccc/Acc	-14,27	0	0	probably_damaging	1	neutral	0,34	neutral	2,56	deleterious	-5,94	deleterious	-6,61	high_impact	5,28	neutral	0,92	damaging	0,13	deleterious	3,63	23,2	0,11	0,4	disease	0,64	disease	0,82	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,07	high_impact	3,6	0,49	0,8	58,95	8,72	P	0,58	P	0,96	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15302	15302	C	T	MI.9512	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	556	186	P	S	Ccc/Tcc	-14,27	0	0	probably_damaging	1	neutral	0,45	neutral	2,52	deleterious	-5,18	deleterious	-6,61	high_impact	4,66	neutral	0,93	damaging	0,1	deleterious	3,82	23,4	0,09	0,4	disease	0,63	disease	0,86	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,18	high_impact	3,04	0,13	0,8	58,95	8,72	N	0,48	N	0,9	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15303	15303	C	T	MI.9513	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	557	186	P	L	cCc/cTc	5,46	1	0	probably_damaging	1	neutral	1	neutral	2,46	deleterious	-6,93	deleterious	-8,27	high_impact	4,93	neutral	0,94	damaging	0,07	deleterious	4,4	24,1	0,06	0,35	neutral	0,47	disease	0,92	disease	0,67	disease	0,72	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,79	low_impact	-3,53	high_impact	1,85	high_impact	3,28	0,64	0,8	58,95	8,72	P	0,6	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15303	15303	C	G	MI.9514	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	557	186	P	R	cCc/cGc	5,46	1	0	probably_damaging	1	neutral	0,28	neutral	2,44	deleterious	-7,25	deleterious	-7,44	high_impact	5,28	neutral	0,93	damaging	0,08	deleterious	3,57	23,1	0,04	0,35	disease	0,77	disease	0,94	disease	0,77	disease	0,79	6	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0	high_impact	3,6	0,3	0,8	58,95	8,72	P	0,66	P	0,8	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15303	15303	C	A	MI.9515	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	557	186	P	H	cCc/cAc	5,46	1	0	probably_damaging	1	neutral	0,63	neutral	2,43	deleterious	-8,44	deleterious	-7,44	high_impact	5,28	neutral	0,91	damaging	0,09	deleterious	4	23,6	0,06	0,35	disease	0,85	disease	0,91	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,35	high_impact	3,6	0,25	0,8	58,95	8,72	P	0,7	P	0,71	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15305	15305	T	C	MI.9516	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	559	187	F	L	Ttc/Ctc	-3,49	0	0	probably_damaging	0,99	neutral	0,98	neutral	3,17	neutral	-1,2	deleterious	-4,94	medium_impact	3,29	neutral	0,97	damaging	0,13	deleterious	3,67	23,2	0,15	0,4	neutral	0,4	disease	0,82	disease	0,62	disease	0,66	3	deleterious	0,99	deleterious	0,5	deleterious	1	deleterious	0,75	low_impact	-2,59	medium_impact	1,14	medium_impact	1,79	0,52	0,8	58,42	8,64	N	0,23	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15305	15305	T	A	MI.9517	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	559	187	F	I	Ttc/Atc	-3,49	0	0	probably_damaging	1	neutral	0,49	neutral	3,09	neutral	-2,2	deleterious	-4,95	high_impact	4,54	neutral	0,94	damaging	0,12	deleterious	4,17	23,8	0,11	0,4	disease	0,71	disease	0,86	disease	0,68	disease	0,71	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,21	high_impact	2,93	0,43	0,8	58,42	8,64	N	0,46	N	0,97	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15305	15305	T	G	MI.9518	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	559	187	F	V	Ttc/Gtc	-3,49	0	0	probably_damaging	1	neutral	0,54	neutral	3,11	neutral	-1,89	deleterious	-5,77	high_impact	5,04	neutral	0,95	damaging	0,14	deleterious	4,04	23,7	0,07	0,35	disease	0,68	disease	0,86	disease	0,69	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,26	high_impact	3,38	0,3	0,8	58,42	8,64	P	0,59	P	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15306	15306	T	G	MI.9519	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	560	187	F	C	tTc/tGc	7,3	1	0	probably_damaging	1	neutral	0,17	neutral	3	deleterious	-4,76	deleterious	-6,6	high_impact	5,24	neutral	0,95	damaging	0,1	deleterious	4,07	23,7	0,03	0,35	disease	0,91	disease	0,85	disease	0,7	disease	0,68	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,15	high_impact	3,56	0,19	0,8	58,42	8,64	P	0,7	P	0,99	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8972	8972	T	C	MI.952	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	446	149	L	P	cTa/cCa	-0,1	0	0	probably_damaging	1	neutral	0,14	neutral	4,19	deleterious	-4,18	deleterious	-6,42	high_impact	3,84	neutral	0,7	neutral	0,38	deleterious	3,94	23,5	0,18	0,65	disease	0,61	disease	0,87	disease	0,69	disease	0,72	4	deleterious	1	neutral	0,07	deleterious	2	deleterious	0,85	low_impact	-3,6	medium_impact	-0,15	high_impact	2,19	0,51	0,9	49,56	8,82	N	0,37	N	1	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15306	15306	T	C	MI.9520	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	560	187	F	S	tTc/tCc	7,3	1	0	probably_damaging	1	neutral	0,42	neutral	3,04	deleterious	-3	deleterious	-6,6	high_impact	5,24	neutral	0,93	damaging	0,09	deleterious	4,14	23,8	0,03	0,35	disease	0,79	disease	0,82	disease	0,67	disease	0,68	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,15	high_impact	3,56	0,31	0,8	58,42	8,64	P	0,7	P	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15306	15306	T	A	MI.9521	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	560	187	F	Y	tTc/tAc	7,3	1	0	probably_damaging	0,99	neutral	1	neutral	3,01	deleterious	-3,09	neutral	-2,48	high_impact	5,04	neutral	0,95	damaging	0,12	deleterious	3,8	23,4	0,15	0,4	disease	0,54	disease	0,81	disease	0,64	disease	0,66	3	deleterious	0,99	deleterious	0,51	deleterious	2	deleterious	0,77	low_impact	-2,59	high_impact	1,85	high_impact	3,38	0,56	0,8	58,42	8,64	P	0,71	P	0,87	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15307	15307	C	G	MI.9522	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	561	187	F	L	ttC/ttG	5,69	1	0	probably_damaging	0,99	neutral	0,98	neutral	3,17	neutral	-1,2	deleterious	-4,94	medium_impact	3,29	neutral	0,97	damaging	0,13	deleterious	3,93	23,5	0,15	0,4	neutral	0,4	disease	0,82	disease	0,62	disease	0,66	3	deleterious	0,99	deleterious	0,5	deleterious	1	deleterious	0,75	low_impact	-2,59	medium_impact	1,14	medium_impact	1,79	0,52	0,8	58,42	8,64	N	0,46	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15307	15307	C	A	MI.9523	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	561	187	F	L	ttC/ttA	5,69	1	0	probably_damaging	0,99	neutral	0,98	neutral	3,17	neutral	-1,2	deleterious	-4,94	medium_impact	3,29	neutral	0,97	damaging	0,13	deleterious	4,29	24	0,15	0,4	neutral	0,4	disease	0,82	disease	0,62	disease	0,66	3	deleterious	0,99	deleterious	0,5	deleterious	1	deleterious	0,75	low_impact	-2,59	medium_impact	1,14	medium_impact	1,79	0,52	0,8	58,42	8,64	N	0,46	N	0,92	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15308	15308	A	T	MI.9524	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	562	188	I	F	Att/Ttt	-5,32	0	0	possibly_damaging	0,66	neutral	0,86	neutral	2,94	neutral	-2,06	deleterious	-2,71	medium_impact	3,36	neutral	0,85	neutral	0,41	deleterious	2,1	16,86	0,13	0,4	disease	0,71	disease	0,82	disease	0,56	disease	0,66	3	neutral	0,6	deleterious	0,6	NA	0	deleterious	0,67	medium_impact	-1	medium_impact	0,65	medium_impact	1,86	0,53	0,8	16,32	15,02	N	0,18	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15308	15308	A	G	MI.9525	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	562	188	I	V	Att/Gtt	-5,32	0	0	benign	0	neutral	0,44	neutral	3,02	neutral	-1,11	neutral	-0,23	neutral_impact	0,68	neutral	0,93	neutral	0,86	neutral	-0,11	1,66	0,34	0,5	neutral	0,27	neutral	0,17	neutral	0,31	neutral	0,27	5	neutral	0,56	deleterious	0,72	neutral	-6	neutral	0,11	high_impact	2,07	medium_impact	0,17	medium_impact	-0,58	0,38	0,8	16,32	15,02	N	0,42	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15308	15308	A	C	MI.9526	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	562	188	I	L	Att/Ctt	-5,32	0	0	benign	0,08	neutral	1	neutral	3,35	neutral	0,65	neutral	-0,86	low_impact	0,91	neutral	0,9	neutral	0,45	deleterious	1,84	15,22	0,2	0,45	neutral	0,45	disease	0,55	neutral	0,29	neutral	0,25	5	neutral	0,08	deleterious	0,96	neutral	-6	neutral	0,19	medium_impact	0,26	high_impact	1,85	medium_impact	-0,37	0,57	0,8	16,32	15,02	N	0,25	N	0,88	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15309	15309	T	A	MI.9527	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	563	188	I	N	aTt/aAt	-0,96	0	0	probably_damaging	0,95	neutral	0,06	neutral	2,88	deleterious	-4,2	deleterious	-4,71	high_impact	4,5	neutral	0,83	neutral	0,41	deleterious	4,18	23,8	0,08	0,35	disease	0,84	disease	0,84	disease	0,54	disease	0,67	3	deleterious	0,99	neutral	0,06	deleterious	2	deleterious	0,79	low_impact	-1,92	medium_impact	-0,43	high_impact	2,89	0,4	0,8	16,32	15,02	N	0,48	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15309	15309	T	G	MI.9528	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	563	188	I	S	aTt/aGt	-0,96	0	0	possibly_damaging	0,81	neutral	0,07	neutral	2,91	neutral	-2,95	deleterious	-3,83	high_impact	4,5	neutral	0,84	neutral	0,39	deleterious	3,95	23,6	0,03	0,35	disease	0,73	disease	0,8	disease	0,53	disease	0,66	3	neutral	0,96	neutral	0,13	deleterious	1	deleterious	0,67	low_impact	-1,32	medium_impact	-0,39	high_impact	2,89	0,3	0,8	16,32	15,02	N	0,45	N	0,98	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15309	15309	T	C	MI.9529	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	563	188	I	T	aTt/aCt	-0,96	0	0	possibly_damaging	0,56	neutral	0,07	neutral	2,92	neutral	-2,59	deleterious	-2,88	medium_impact	3,19	neutral	0,81	neutral	0,46	deleterious	2,88	21,8	0,07	0,35	disease	0,66	disease	0,6	neutral	0,47	neutral	0,35	3	neutral	0,93	neutral	0,26	NA	0	deleterious	0,51	medium_impact	-0,83	medium_impact	-0,39	medium_impact	1,7	0,39	0,8	16,32	15,02	N	0,36	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8974	8974	C	G	MI.953	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	448	150	L	V	Ctc/Gtc	-6,58	0	0	benign	0,07	neutral	0,25	neutral	4,26	neutral	-0,84	neutral	-1,28	low_impact	1,75	neutral	0,91	neutral	0,76	neutral	1,55	13,58	0,39	0,65	disease	0,51	disease	0,62	neutral	0,42	neutral	0,47	1	neutral	0,73	deleterious	0,59	neutral	-6	neutral	0,25	medium_impact	0,31	medium_impact	0,02	medium_impact	0,4	0,68	0,9	15,93	11,92	N	0,33	N	0,45	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15310	15310	T	A	MI.9530	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	564	188	I	M	atT/atA	2,25	0,03	0,01	possibly_damaging	0,81	neutral	0,07	neutral	2,92	neutral	-2,43	neutral	-1,41	medium_impact	2,05	neutral	0,89	neutral	0,52	deleterious	2,22	17,61	0,25	0,45	disease	0,69	neutral	0,49	neutral	0,33	neutral	0,45	1	neutral	0,96	neutral	0,13	NA	0	deleterious	0,58	low_impact	-1,32	medium_impact	-0,39	medium_impact	0,67	0,47	0,8	16,32	15,02	N	0,47	N	0,83	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15310	15310	T	G	MI.9531	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	564	188	I	M	atT/atG	2,25	0,03	0,01	possibly_damaging	0,81	neutral	0,07	neutral	2,92	neutral	-2,43	neutral	-1,41	medium_impact	2,05	neutral	0,89	neutral	0,52	deleterious	1,89	15,56	0,25	0,45	disease	0,69	neutral	0,49	neutral	0,33	neutral	0,45	1	neutral	0,96	neutral	0,13	NA	0	deleterious	0,58	low_impact	-1,32	medium_impact	-0,39	medium_impact	0,67	0,47	0,8	16,32	15,02	N	0,48	N	0,83	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15311	15311	A	C	MI.9532	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	565	189	I	L	Att/Ctt	-6,93	0	0	benign	0,23	neutral	1	neutral	3,1	neutral	-0,17	neutral	-1,52	low_impact	1,8	neutral	0,94	neutral	0,43	deleterious	2,04	16,44	0,19	0,45	neutral	0,22	disease	0,71	neutral	0,31	neutral	0,35	3	neutral	0,23	deleterious	0,89	neutral	-6	neutral	0,19	medium_impact	-0,24	high_impact	1,85	medium_impact	0,44	0,33	0,8	27,89	11,64	N	0,23	N	0,88	polymorphism	1	0,02	rs35070048	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15311	15311	A	T	MI.9533	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	565	189	I	F	Att/Ttt	-6,93	0	0	possibly_damaging	0,84	neutral	0,4	neutral	2,77	deleterious	-3,19	deleterious	-3,23	high_impact	4,87	neutral	0,95	neutral	0,43	deleterious	3,54	23,1	0,11	0,4	disease	0,63	disease	0,85	disease	0,59	disease	0,68	4	neutral	0,84	neutral	0,28	deleterious	1	deleterious	0,74	low_impact	-1,4	medium_impact	0,13	high_impact	3,23	0,41	0,8	27,89	11,64	P	0,67	P	0,97	polymorphism	1	0,06	rs35070048	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15311	15311	A	G	MI.9534	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	565	189	I	V	Att/Gtt	-6,93	0	0	benign	0,1	neutral	0,49	neutral	2,89	neutral	-1,52	neutral	-0,61	low_impact	1,57	neutral	0,97	neutral	0,95	deleterious	-0,02	2,42	0,23	0,45	neutral	0,36	neutral	0,26	neutral	0,35	neutral	0,4	2	neutral	0,44	deleterious	0,7	neutral	-6	neutral	0,16	medium_impact	0,16	medium_impact	0,21	medium_impact	0,23	0,32	0,8	27,89	11,64	N	0,32	N	0,83	polymorphism	1	0,01	rs35070048	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15312	15312	T	G	MI.9535	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	566	189	I	S	aTt/aGt	0,41	0,06	0	probably_damaging	0,93	neutral	0,16	neutral	2,78	deleterious	-3,42	deleterious	-4,75	high_impact	4,12	neutral	0,94	neutral	0,43	deleterious	4,19	23,8	0,03	0,35	disease	0,68	disease	0,84	disease	0,57	disease	0,66	3	neutral	0,96	neutral	0,12	deleterious	2	deleterious	0,73	low_impact	-1,78	medium_impact	-0,17	high_impact	2,55	0,2	0,8	27,89	11,64	N	0,47	N	0,98	polymorphism	1	0,09	.	.	.	.	.	thyroid tumor	.	.	.	.	.	.	.	.	.
chrM	15312	15312	T	A	MI.9536	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	566	189	I	N	aTt/aAt	0,41	0,06	0	probably_damaging	0,97	neutral	0,05	neutral	2,74	deleterious	-4,71	deleterious	-5,58	high_impact	4,32	neutral	0,93	neutral	0,44	deleterious	4,23	23,9	0,07	0,35	disease	0,81	disease	0,86	disease	0,57	disease	0,68	4	deleterious	0,99	neutral	0,04	deleterious	2	deleterious	0,8	low_impact	-2,14	medium_impact	-0,47	high_impact	2,73	0,23	0,8	27,89	11,64	N	0,51	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15312	15312	T	C	MI.9537	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	566	189	I	T	aTt/aCt	0,41	0,06	0	benign	0,38	neutral	0,07	neutral	2,78	neutral	-2,22	deleterious	-3,82	high_impact	3,55	neutral	0,96	neutral	0,55	deleterious	3,25	22,8	0,06	0,35	disease	0,61	disease	0,69	disease	0,51	neutral	0,46	1	neutral	0,92	neutral	0,35	neutral	-2	neutral	0,3	medium_impact	-0,53	medium_impact	-0,39	high_impact	2,03	0,18	0,8	27,89	11,64	N	0,43	N	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15313	15313	T	A	MI.9538	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	567	189	I	M	atT/atA	7,3	0,95	0	probably_damaging	0,92	neutral	0,37	neutral	2,78	neutral	-2,59	neutral	-2,26	medium_impact	2,6	neutral	0,95	neutral	0,44	deleterious	3,55	23,1	0,19	0,45	disease	0,62	disease	0,69	neutral	0,48	neutral	0,45	1	neutral	0,92	neutral	0,23	deleterious	1	deleterious	0,65	low_impact	-1,72	medium_impact	0,1	medium_impact	1,17	0,36	0,8	27,89	11,64	N	0,5	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15313	15313	T	G	MI.9539	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	567	189	I	M	atT/atG	7,3	0,95	0	probably_damaging	0,92	neutral	0,37	neutral	2,78	neutral	-2,59	neutral	-2,26	medium_impact	2,6	neutral	0,95	neutral	0,44	deleterious	3,27	22,8	0,19	0,45	disease	0,62	disease	0,69	neutral	0,48	neutral	0,45	1	neutral	0,92	neutral	0,23	deleterious	1	deleterious	0,65	low_impact	-1,72	medium_impact	0,1	medium_impact	1,17	0,36	0,8	27,89	11,64	N	0,5	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8974	8974	C	A	MI.954	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	448	150	L	I	Ctc/Atc	-6,58	0	0	benign	0,07	neutral	0,57	neutral	4,24	neutral	-1,06	neutral	-0,39	low_impact	1,15	neutral	0,89	neutral	0,76	deleterious	2,21	17,56	0,32	0,65	neutral	0,4	neutral	0,49	neutral	0,32	neutral	0,47	1	neutral	0,36	deleterious	0,75	neutral	-6	neutral	0,22	medium_impact	0,31	medium_impact	0,36	medium_impact	-0,11	0,75	0,9	15,93	11,92	N	0,27	N	0,32	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15314	15314	G	T	MI.9540	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	568	190	A	S	Gca/Tca	-3,03	0	0,03	benign	0,2	neutral	0,18	neutral	3,07	neutral	-2,12	neutral	-1,67	low_impact	1,25	neutral	0,97	neutral	0,95	deleterious	1,88	15,48	0,21	0,45	neutral	0,39	disease	0,61	neutral	0,28	neutral	0,4	2	neutral	0,79	deleterious	0,49	neutral	-6	neutral	0,19	medium_impact	-0,17	medium_impact	-0,14	medium_impact	-0,06	0,38	0,8	13,42	16,99	N	0,46	N	0,44	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15314	15314	G	C	MI.9541	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	568	190	A	P	Gca/Cca	-3,03	0	0,03	possibly_damaging	0,58	neutral	0,28	neutral	3,02	deleterious	-3,78	deleterious	-3,02	high_impact	4,09	neutral	0,98	neutral	0,32	deleterious	3,65	23,2	0,06	0,35	disease	0,65	disease	0,92	disease	0,56	disease	0,71	4	neutral	0,72	neutral	0,35	deleterious	1	deleterious	0,56	medium_impact	-0,86	medium_impact	0	high_impact	2,52	0,46	0,8	13,42	16,99	N	0,44	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15314	15314	G	A	MI.9542	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	568	190	A	T	Gca/Aca	-3,03	0	0,03	benign	0	neutral	0,22	neutral	3,07	neutral	-0,99	neutral	-1,68	low_impact	1,12	neutral	0,99	neutral	0,97	deleterious	2,02	16,36	0,15	0,4	neutral	0,27	neutral	0,45	neutral	0,28	neutral	0,46	1	neutral	0,78	deleterious	0,61	neutral	-6	neutral	0,13	high_impact	2,07	medium_impact	-0,08	medium_impact	-0,18	0,79	0,85	13,42	16,99	P	0,56	P	0,02	polymorphism	1	0,02	rs527236176	Likely pathogenic	Neoplasm_of_ovary	RCV000133418.1	Gene:MedGen:OMIM:SNOMED_CT	.	.	.	21,69	.	.	.	.	.	.
chrM	15315	15315	C	A	MI.9543	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	569	190	A	E	gCa/gAa	-3,03	0	0	possibly_damaging	0,47	neutral	0,11	neutral	3,03	deleterious	-3,44	deleterious	-2,99	high_impact	4,43	neutral	0,93	neutral	0,44	deleterious	4,25	23,9	0,05	0,35	disease	0,52	disease	0,9	disease	0,58	disease	0,71	4	neutral	0,88	neutral	0,32	deleterious	1	deleterious	0,47	medium_impact	-0,68	medium_impact	-0,27	high_impact	2,83	0,47	0,8	13,42	16,99	N	0,5	N	0,49	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15315	15315	C	G	MI.9544	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	569	190	A	G	gCa/gGa	-3,03	0	0	benign	0,08	neutral	0,26	neutral	3,15	neutral	-1,38	deleterious	-2,81	high_impact	3,75	neutral	0,93	neutral	0,5	deleterious	2,25	17,85	0,16	0,45	disease	0,59	disease	0,79	neutral	0,47	disease	0,63	3	neutral	0,71	deleterious	0,59	neutral	-2	neutral	0,23	medium_impact	0,26	medium_impact	-0,02	high_impact	2,21	0,68	0,85	13,42	16,99	N	0,37	N	0,4	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15315	15315	C	T	MI.9545	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	569	190	A	V	gCa/gTa	-3,03	0	0	benign	0,13	neutral	0,7	neutral	3,18	neutral	-0,15	neutral	-1,17	low_impact	1,07	neutral	0,97	neutral	0,82	deleterious	2,61	20,2	0,16	0,45	neutral	0,24	disease	0,7	neutral	0,28	neutral	0,42	2	neutral	0,18	deleterious	0,79	neutral	-6	neutral	0,22	medium_impact	0,04	medium_impact	0,42	medium_impact	-0,22	0,73	0,85	13,42	16,99	N	0,29	N	0,23	polymorphism	1	0,01	rs879191792	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15317	15317	G	C	MI.9546	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	571	191	A	P	Gcc/Ccc	-2,11	0	0	possibly_damaging	0,76	neutral	0,18	neutral	2,92	deleterious	-4,22	deleterious	-3,07	high_impact	4,05	neutral	0,94	damaging	0,27	deleterious	3,74	23,3	0,03	0,35	disease	0,71	disease	0,94	disease	0,68	disease	0,76	5	neutral	0,87	neutral	0,21	deleterious	1	deleterious	0,77	low_impact	-1,2	medium_impact	-0,14	high_impact	2,48	0,55	0,8	23,68	8,7	N	0,42	N	0,98	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15317	15317	G	T	MI.9547	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	571	191	A	S	Gcc/Tcc	-2,11	0	0	benign	0,36	neutral	0,22	neutral	2,97	neutral	-2,06	neutral	-1,4	medium_impact	2,44	neutral	0,96	neutral	0,48	deleterious	3,36	22,9	0,2	0,45	neutral	0,47	disease	0,81	neutral	0,45	disease	0,58	2	neutral	0,74	neutral	0,43	neutral	-3	neutral	0,3	medium_impact	-0,5	medium_impact	-0,08	medium_impact	1,02	0,48	0,8	23,68	8,7	N	0,37	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15317	15317	G	A	MI.9548	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	571	191	A	T	Gcc/Acc	-2,11	0	0	benign	0,02	neutral	0,3	neutral	2,98	neutral	-1,88	neutral	-2,5	medium_impact	3,02	neutral	0,98	neutral	0,63	deleterious	3,88	23,5	0,1	0,4	neutral	0,47	disease	0,79	neutral	0,48	disease	0,54	1	neutral	0,69	deleterious	0,64	neutral	-3	neutral	0,19	medium_impact	0,85	medium_impact	0,02	medium_impact	1,55	0,58	0,8	23,68	8,7	N	0,4	N	0,79	polymorphism	1	0,04	rs2853507	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15318	15318	C	T	MI.9549	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	572	191	A	V	gCc/gTc	5,92	1	0	benign	0,26	neutral	0,43	neutral	3,12	neutral	-0,4	deleterious	-2,91	medium_impact	2,42	neutral	0,95	neutral	0,51	deleterious	4,11	23,7	0,09	0,35	neutral	0,33	disease	0,88	neutral	0,39	disease	0,69	4	neutral	0,48	deleterious	0,59	neutral	-3	deleterious	0,46	medium_impact	-0,31	medium_impact	0,16	medium_impact	1	0,56	0,8	23,68	8,7	N	0,54	P	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8974	8974	C	T	MI.955	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	448	150	L	F	Ctc/Ttc	-6,58	0	0	benign	0	neutral	0,79	neutral	4,45	neutral	0,25	neutral	2,75	neutral_impact	-0,18	neutral	0,85	neutral	0,98	neutral	-0,64	0,1	0,36	0,65	neutral	0,26	neutral	0,12	neutral	0,28	neutral	0,25	5	neutral	0,2	deleterious	0,9	neutral	-6	neutral	0,15	high_impact	2,09	medium_impact	0,62	low_impact	-1,25	0,59	0,9	15,93	11,92	N	0,29	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15318	15318	C	A	MI.9550	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	572	191	A	D	gCc/gAc	5,92	1	0	possibly_damaging	0,69	neutral	0,1	neutral	2,91	deleterious	-4,71	deleterious	-3,2	high_impact	4,86	neutral	0,9	neutral	0,37	deleterious	4,52	24,3	0,03	0,35	disease	0,63	disease	0,95	disease	0,67	disease	0,79	6	neutral	0,91	neutral	0,21	deleterious	1	deleterious	0,72	low_impact	-1,06	medium_impact	-0,3	high_impact	3,22	0,35	0,8	23,68	8,7	P	0,68	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15318	15318	C	G	MI.9551	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	572	191	A	G	gCc/gGc	5,92	1	0	benign	0,17	neutral	0,27	neutral	3	neutral	-1,66	neutral	0,06	neutral_impact	0,39	neutral	0,96	neutral	0,53	neutral	0,98	10,53	0,16	0,45	neutral	0,29	neutral	0,38	neutral	0,29	neutral	0,4	2	neutral	0,68	deleterious	0,55	neutral	-6	neutral	0,21	medium_impact	-0,09	medium_impact	-0,01	medium_impact	-0,84	0,62	0,8	23,68	8,7	P	0,6	P	0,83	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15320	15320	C	G	MI.9552	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	574	192	L	V	Cta/Gta	-11,28	0	0	possibly_damaging	0,57	neutral	0,6	neutral	2,77	deleterious	-5,3	neutral	-0,57	low_impact	1,15	neutral	0,96	neutral	0,58	deleterious	2,06	16,61	0,33	0,5	neutral	0,39	neutral	0,39	neutral	0,36	neutral	0,46	1	neutral	0,51	deleterious	0,52	neutral	-3	neutral	0,42	medium_impact	-0,85	medium_impact	0,32	medium_impact	-0,15	0,48	0,8	16,32	15,77	N	0,29	N	0,57	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15320	15320	C	A	MI.9553	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	574	192	L	M	Cta/Ata	-11,28	0	0	probably_damaging	0,94	neutral	0,29	neutral	2,68	deleterious	-5,97	neutral	-0,26	neutral_impact	0,63	neutral	0,93	neutral	0,75	deleterious	2,39	18,77	0,27	0,45	neutral	0,43	neutral	0,19	neutral	0,27	neutral	0,37	3	neutral	0,95	neutral	0,18	neutral	-2	deleterious	0,65	low_impact	-1,85	medium_impact	0,01	medium_impact	-0,62	0,5	0,8	16,32	15,77	N	0,47	N	0,64	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15321	15321	T	A	MI.9554	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	575	192	L	Q	cTa/cAa	-2,57	0	0	probably_damaging	0,92	neutral	0,31	neutral	2,61	deleterious	-8,09	neutral	-2,37	high_impact	4,58	neutral	0,94	neutral	0,44	deleterious	4	23,6	0,03	0,35	disease	0,72	disease	0,74	disease	0,56	disease	0,68	4	neutral	0,93	neutral	0,2	deleterious	2	deleterious	0,72	low_impact	-1,72	medium_impact	0,03	high_impact	2,97	0,25	0,8	16,32	15,77	N	0,47	N	0,91	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15321	15321	T	G	MI.9555	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	575	192	L	R	cTa/cGa	-2,57	0	0	probably_damaging	0,92	neutral	0,36	neutral	2,61	deleterious	-7,87	deleterious	-2,55	high_impact	4,58	neutral	0,94	neutral	0,41	deleterious	4,11	23,7	0,02	0,35	disease	0,71	disease	0,9	disease	0,69	disease	0,75	5	neutral	0,92	neutral	0,22	deleterious	2	deleterious	0,81	low_impact	-1,72	medium_impact	0,09	high_impact	2,97	0,18	0,8	16,32	15,77	N	0,45	N	0,99	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15321	15321	T	C	MI.9556	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	575	192	L	P	cTa/cCa	-2,57	0	0	benign	0,03	neutral	0,23	neutral	2,61	deleterious	-8,49	deleterious	-2,94	high_impact	4,24	neutral	0,92	neutral	0,34	deleterious	3,84	23,4	0,02	0,35	disease	0,79	disease	0,88	disease	0,68	disease	0,76	5	neutral	0,76	deleterious	0,6	neutral	-2	neutral	0,32	medium_impact	0,68	medium_impact	-0,06	high_impact	2,66	0,18	0,8	16,32	15,77	N	0,37	N	0,95	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15323	15323	G	T	MI.9557	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	577	193	A	S	Gca/Tca	-4,86	0	0,07	benign	0,2	neutral	0,41	neutral	3,15	neutral	4,67	neutral	0,36	neutral_impact	-0,44	neutral	0,93	neutral	0,54	deleterious	1,94	15,85	0,25	0,45	neutral	0,22	neutral	0,36	neutral	0,21	neutral	0,45	1	neutral	0,51	deleterious	0,61	neutral	-6	neutral	0,17	medium_impact	-0,17	medium_impact	0,14	low_impact	-1,59	0,59	0,8	22,11	27,24	N	0,37	N	0,55	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15323	15323	G	C	MI.9558	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	577	193	A	P	Gca/Cca	-4,86	0	0,07	possibly_damaging	0,58	neutral	0,2	neutral	3,09	neutral	-2,13	neutral	-1,45	medium_impact	3,17	neutral	0,94	neutral	0,3	deleterious	3,67	23,3	0,06	0,35	disease	0,65	disease	0,91	disease	0,62	disease	0,78	6	neutral	0,8	neutral	0,31	NA	0	deleterious	0,66	medium_impact	-0,86	medium_impact	-0,1	medium_impact	1,69	0,55	0,8	22,11	27,24	N	0,35	N	0,82	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15323	15323	G	A	MI.9559	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	577	193	A	T	Gca/Aca	-4,86	0	0,07	benign	0,01	neutral	0,47	neutral	3,16	neutral	-0,81	neutral	2,05	neutral_impact	-0,86	neutral	0,98	neutral	0,91	neutral	1,5	13,31	0,15	0,45	neutral	0,27	neutral	0,1	neutral	0,19	neutral	0,28	5	neutral	0,52	deleterious	0,73	neutral	-6	neutral	0,11	medium_impact	1,13	medium_impact	0,19	low_impact	-1,97	0,68	0,85	22,11	27,24	N	0,49	N	0	polymorphism	1	0	rs527236177	Likely pathogenic	Familial_cancer_of_breast	RCV000133419.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	11,14	.	.	.	.	.	.
chrM	8975	8975	T	G	MI.956	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	449	150	L	R	cTc/cGc	0,13	0,02	0	possibly_damaging	0,46	deleterious	0	neutral	4,1	deleterious	-4,01	deleterious	-3,47	medium_impact	3,46	neutral	0,79	neutral	0,46	deleterious	2,57	19,95	0,13	0,65	disease	0,82	disease	0,91	disease	0,73	disease	0,81	6	deleterious	1	neutral	0,27	deleterious	4	deleterious	0,61	medium_impact	-0,69	low_impact	-1,4	medium_impact	1,87	0,64	0,9	15,93	11,92	N	0,32	N	0,79	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15324	15324	C	G	MI.9560	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	578	193	A	G	gCa/gGa	0,18	0	0	benign	0,13	neutral	0,36	neutral	3,13	neutral	-0,96	neutral	-1,83	medium_impact	2,96	neutral	0,92	neutral	0,5	deleterious	2,21	17,55	0,2	0,45	disease	0,56	disease	0,69	neutral	0,38	neutral	0,45	1	neutral	0,58	deleterious	0,62	neutral	-3	neutral	0,24	medium_impact	0,04	medium_impact	0,09	medium_impact	1,49	0,65	0,8	22,11	27,24	N	0,33	N	0,5	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15324	15324	C	A	MI.9561	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	578	193	A	E	gCa/gAa	0,18	0	0	possibly_damaging	0,6	neutral	0,3	neutral	3,09	neutral	-1,55	neutral	-1,33	medium_impact	3,17	neutral	0,93	neutral	0,45	deleterious	4,41	24,1	0,06	0,35	disease	0,5	disease	0,87	disease	0,62	disease	0,77	5	neutral	0,72	neutral	0,35	NA	0	deleterious	0,47	medium_impact	-0,9	medium_impact	0,02	medium_impact	1,69	0,48	0,8	22,11	27,24	N	0,34	N	0,73	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15324	15324	C	T	MI.9562	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	578	193	A	V	gCa/gTa	0,18	0	0	benign	0	neutral	0,56	neutral	3,34	neutral	-1,58	neutral	-0,37	neutral_impact	-0,84	neutral	0,98	neutral	0,97	neutral	1,35	12,54	0,13	0,4	neutral	0,14	neutral	0,43	neutral	0,26	neutral	0,44	1	neutral	0,43	deleterious	0,78	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,28	low_impact	-1,96	0,57	0,8	22,11	27,24	N	0,36	N	0,03	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15326	15326	A	T	MI.9563	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	580	194	T	S	Aca/Tca	-7,16	0	0,23	benign	0,4	neutral	0,52	neutral	3,13	neutral	-0,38	neutral	-0,52	neutral_impact	0,06	neutral	0,93	neutral	0,63	neutral	1,42	12,91	0,32	0,5	neutral	0,21	neutral	0,33	neutral	0,37	neutral	0,44	1	neutral	0,43	deleterious	0,56	neutral	-6	neutral	0,26	medium_impact	-0,57	medium_impact	0,24	low_impact	-1,14	0,48	0,8	25	20,03	N	0,32	N	0,23	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15326	15326	A	G	MI.9564	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	580	194	T	A	Aca/Gca	-7,16	0	0,23	benign	0,02	neutral	0,49	neutral	3,23	neutral	0,41	neutral	0,31	neutral_impact	-1,01	neutral	0,99	neutral	0,98	deleterious	0,1	3,59	0,24	0,45	neutral	0,29	neutral	0,21	neutral	0,26	neutral	0,35	3	neutral	0,49	deleterious	0,74	neutral	-6	neutral	0,12	medium_impact	0,85	medium_impact	0,21	low_impact	-2,11	0,28	0,8	25	20,03	N	0,4	N	0,16	polymorphism	1	0	rs2853508	Likely pathogenic	Familial_cancer_of_breast	RCV000128807.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	16,34	.	.	.	.	.	.
chrM	15326	15326	A	C	MI.9565	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	580	194	T	P	Aca/Cca	-7,16	0	0,23	possibly_damaging	0,79	neutral	0,15	neutral	3,07	neutral	-1,32	neutral	-1,4	low_impact	1,59	neutral	0,93	neutral	0,45	neutral	1,53	13,46	0,07	0,35	neutral	0,41	disease	0,81	disease	0,62	disease	0,76	5	neutral	0,9	neutral	0,18	neutral	-3	deleterious	0,59	low_impact	-1,27	medium_impact	-0,19	medium_impact	0,25	0,3	0,8	25	20,03	N	0,37	N	0,8	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15327	15327	C	T	MI.9566	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	581	194	T	M	aCa/aTa	-5,55	0	0	probably_damaging	0,94	neutral	0,42	neutral	3,16	neutral	1,19	neutral	2,13	neutral_impact	-2,42	neutral	0,93	neutral	0,93	neutral	-0,74	0,06	0,15	0,4	neutral	0,2	neutral	0,11	neutral	0,22	neutral	0,24	5	neutral	0,94	neutral	0,24	neutral	-2	deleterious	0,58	low_impact	-1,85	medium_impact	0,15	low_impact	-3,39	0,49	0,8	25	20,03	N	0,36	N	0,02	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15327	15327	C	A	MI.9567	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	581	194	T	K	aCa/aAa	-5,55	0	0	possibly_damaging	0,52	neutral	0,33	neutral	3,06	neutral	-0,61	neutral	-1,02	low_impact	1,59	neutral	0,94	neutral	0,55	deleterious	2,51	19,5	0,11	0,4	neutral	0,32	disease	0,68	disease	0,52	disease	0,57	1	neutral	0,66	neutral	0,41	neutral	-3	deleterious	0,44	medium_impact	-0,76	medium_impact	0,06	medium_impact	0,25	0,48	0,8	25	20,03	N	0,34	N	0,74	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15329	15329	C	T	MI.9568	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	583	195	L	F	Ctc/Ttc	-8,99	0	0	probably_damaging	1	neutral	0,74	neutral	3,08	neutral	-2,28	neutral	-2,29	medium_impact	2,69	neutral	0,94	neutral	0,67	deleterious	3,87	23,5	0,23	0,45	neutral	0,37	disease	0,68	disease	0,56	disease	0,68	4	deleterious	1	neutral	0,37	deleterious	1	deleterious	0,73	low_impact	-3,53	medium_impact	0,47	medium_impact	1,25	0,48	0,8	22,37	27,75	N	0,26	N	0,47	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15329	15329	C	G	MI.9569	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	583	195	L	V	Ctc/Gtc	-8,99	0	0	probably_damaging	1	neutral	0,66	neutral	3,12	neutral	0,51	neutral	-0,07	neutral_impact	0,4	neutral	0,97	neutral	0,94	deleterious	0,51	7,5	0,26	0,45	neutral	0,2	neutral	0,09	neutral	0,29	neutral	0,29	4	deleterious	1	neutral	0,33	neutral	-2	deleterious	0,64	low_impact	-3,53	medium_impact	0,38	medium_impact	-0,83	0,57	0,8	22,37	27,75	N	0,37	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8975	8975	T	C	MI.957	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	449	150	L	P	cTc/cCc	0,13	0,02	0	possibly_damaging	0,64	deleterious	0	neutral	4,09	deleterious	-4,57	deleterious	-4,38	medium_impact	3,46	neutral	0,8	neutral	0,39	deleterious	3,67	23,3	0,15	0,65	disease	0,86	disease	0,92	disease	0,73	disease	0,82	6	deleterious	1	neutral	0,18	deleterious	4	deleterious	0,73	medium_impact	-0,99	low_impact	-1,4	medium_impact	1,87	0,61	0,9	15,93	11,92	N	0,36	N	0,95	disease_causing	0,98	0,26	rs1981459	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15329	15329	C	A	MI.9570	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	583	195	L	I	Ctc/Atc	-8,99	0	0	probably_damaging	1	neutral	0,74	neutral	3,14	neutral	3,77	neutral	0,22	neutral_impact	-0,26	neutral	0,94	neutral	0,94	deleterious	2,23	17,68	0,31	0,45	neutral	0,15	neutral	0,12	neutral	0,22	neutral	0,28	4	deleterious	1	neutral	0,37	neutral	-2	deleterious	0,65	low_impact	-3,53	medium_impact	0,47	low_impact	-1,43	0,43	0,8	22,37	27,75	N	0,33	N	0,21	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15330	15330	T	G	MI.9571	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	584	195	L	R	cTc/cGc	-0,96	0	0	probably_damaging	1	neutral	0,28	neutral	2,93	deleterious	-3,62	deleterious	-4,09	high_impact	4,42	neutral	0,94	neutral	0,52	deleterious	4,13	23,8	0,02	0,35	disease	0,64	disease	0,9	disease	0,68	disease	0,77	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0	high_impact	2,82	0,17	0,8	22,37	27,75	N	0,52	P	0,87	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15330	15330	T	A	MI.9572	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	584	195	L	H	cTc/cAc	-0,96	0	0	probably_damaging	1	neutral	0,7	neutral	2,92	deleterious	-4,6	deleterious	-4,46	high_impact	4,08	neutral	0,93	neutral	0,54	deleterious	4,28	24	0,05	0,35	disease	0,71	disease	0,75	disease	0,65	disease	0,71	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,42	high_impact	2,51	0,24	0,8	22,37	27,75	N	0,31	N	0,8	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15330	15330	T	C	MI.9573	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	584	195	L	P	cTc/cCc	-0,96	0	0	probably_damaging	1	neutral	0,17	neutral	2,93	deleterious	-4,06	deleterious	-4,21	high_impact	4,08	neutral	0,93	neutral	0,42	deleterious	3,89	23,5	0,02	0,35	disease	0,71	disease	0,89	disease	0,69	disease	0,77	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,15	high_impact	2,51	0,27	0,8	22,37	27,75	N	0,46	N	0,93	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15332	15332	C	G	MI.9574	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	586	196	H	D	Cac/Gac	-12,66	0	0	probably_damaging	1	neutral	0,21	neutral	2,27	deleterious	-7,01	deleterious	-7,42	high_impact	5,64	neutral	0,84	damaging	0,11	deleterious	3,7	23,3	0,05	0,35	disease	0,7	disease	0,88	disease	0,81	disease	0,75	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,09	high_impact	3,93	0,24	0,8	58,42	8,76	P	0,61	P	0,98	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15332	15332	C	A	MI.9575	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	586	196	H	N	Cac/Aac	-12,66	0	0	probably_damaging	1	neutral	0,31	neutral	2,27	deleterious	-7,34	deleterious	-5,77	high_impact	5,29	neutral	0,86	damaging	0,13	deleterious	3,57	23,1	0,16	0,45	neutral	0,46	disease	0,86	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,03	high_impact	3,61	0,31	0,8	58,42	8,76	P	0,63	P	0,97	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15332	15332	C	T	MI.9576	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	586	196	H	Y	Cac/Tac	-12,66	0	0	probably_damaging	1	neutral	1	neutral	2,24	deleterious	-6,87	deleterious	-4,94	high_impact	5,09	neutral	0,87	damaging	0,13	deleterious	3,38	23	0,1	0,4	disease	0,59	disease	0,89	disease	0,77	disease	0,73	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,84	low_impact	-3,53	high_impact	1,85	high_impact	3,43	0,2	0,8	58,42	8,76	P	0,63	P	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15333	15333	A	C	MI.9577	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	587	196	H	P	cAc/cCc	5,46	1	0	probably_damaging	1	neutral	0,21	neutral	2,24	deleterious	-8,14	deleterious	-8,24	high_impact	4,95	neutral	0,88	damaging	0,08	deleterious	3,53	23,1	0,04	0,35	disease	0,82	disease	0,9	disease	0,84	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,09	high_impact	3,3	0,2	0,8	58,42	8,76	P	0,65	P	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15333	15333	A	T	MI.9578	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	587	196	H	L	cAc/cTc	5,46	1	0	probably_damaging	1	neutral	0,66	neutral	2,26	deleterious	-7,23	deleterious	-9,06	high_impact	5,64	neutral	0,88	damaging	0,11	deleterious	4,03	23,7	0,04	0,35	disease	0,62	disease	0,93	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,38	high_impact	3,93	0,14	0,8	58,42	8,76	P	0,67	P	0,92	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15333	15333	A	G	MI.9579	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	587	196	H	R	cAc/cGc	5,46	1	0	probably_damaging	1	neutral	0,35	neutral	2,3	deleterious	-6,87	deleterious	-6,59	high_impact	5,29	neutral	0,87	damaging	0,09	deleterious	3,18	22,7	0,06	0,35	disease	0,65	disease	0,9	disease	0,8	disease	0,75	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,08	high_impact	3,61	0,26	0,8	58,42	8,76	P	0,71	P	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8975	8975	T	A	MI.958	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	449	150	L	H	cTc/cAc	0,13	0,02	0	possibly_damaging	0,63	deleterious	0	neutral	4,09	deleterious	-4,57	neutral	-2,46	medium_impact	3,46	neutral	0,81	neutral	0,5	deleterious	3,94	23,5	0,17	0,65	disease	0,86	disease	0,8	disease	0,7	disease	0,78	6	deleterious	1	neutral	0,19	deleterious	4	deleterious	0,6	medium_impact	-0,98	low_impact	-1,4	medium_impact	1,87	0,64	0,9	15,93	11,92	N	0,31	N	0,71	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15334	15334	C	G	MI.9580	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	588	196	H	Q	caC/caG	8,44	1	0	probably_damaging	1	neutral	0,3	neutral	2,3	deleterious	-7,37	deleterious	-6,59	high_impact	5,09	neutral	0,91	damaging	0,12	deleterious	3,27	22,8	0,1	0,4	disease	0,67	disease	0,86	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,02	high_impact	3,43	0,39	0,8	58,42	8,76	P	0,7	P	0,94	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15334	15334	C	A	MI.9581	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	588	196	H	Q	caC/caA	8,44	1	0	probably_damaging	1	neutral	0,3	neutral	2,3	deleterious	-7,37	deleterious	-6,59	high_impact	5,09	neutral	0,91	damaging	0,12	deleterious	3,6	23,2	0,1	0,4	disease	0,67	disease	0,86	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,02	high_impact	3,43	0,39	0,8	58,42	8,76	P	0,71	P	0,94	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15335	15335	C	T	MI.9582	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	589	197	L	F	Ctc/Ttc	-1,19	0	0	benign	0,01	neutral	0,72	neutral	3,03	deleterious	-6,13	deleterious	-3,18	high_impact	4,49	neutral	0,95	neutral	0,49	deleterious	3,75	23,3	0,11	0,4	disease	0,73	disease	0,74	neutral	0,41	neutral	0,47	1	neutral	0,25	deleterious	0,86	neutral	-2	neutral	0,29	medium_impact	1,13	medium_impact	0,44	high_impact	2,88	0,39	0,8	58,68	8,52	N	0,35	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15335	15335	C	A	MI.9583	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	589	197	L	I	Ctc/Atc	-1,19	0	0	benign	0,2	neutral	0,44	neutral	2,98	deleterious	-5,02	neutral	-1,56	medium_impact	2,22	neutral	0,94	neutral	0,46	deleterious	3,91	23,5	0,23	0,45	neutral	0,39	disease	0,68	neutral	0,34	neutral	0,4	2	neutral	0,47	deleterious	0,62	neutral	-3	neutral	0,28	medium_impact	-0,17	medium_impact	0,17	medium_impact	0,82	0,54	0,8	58,68	8,52	N	0,33	N	0,86	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15335	15335	C	G	MI.9584	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	589	197	L	V	Ctc/Gtc	-1,19	0	0	benign	0,08	neutral	0,54	neutral	3,03	deleterious	-5,3	neutral	-2,33	medium_impact	3,35	neutral	0,95	neutral	0,47	neutral	1,72	14,54	0,19	0,45	disease	0,61	disease	0,64	neutral	0,5	neutral	0,48	0	neutral	0,38	deleterious	0,73	neutral	-3	neutral	0,28	medium_impact	0,26	medium_impact	0,26	medium_impact	1,85	0,5	0,8	58,68	8,52	N	0,25	N	0,91	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15336	15336	T	C	MI.9585	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	590	197	L	P	cTc/cCc	-0,73	0	0	possibly_damaging	0,9	neutral	0,21	neutral	2,84	deleterious	-8,49	deleterious	-5,55	high_impact	4,66	neutral	0,93	neutral	0,29	deleterious	3,87	23,5	0,01	0,35	disease	0,93	disease	0,86	disease	0,72	disease	0,76	5	neutral	0,94	neutral	0,16	deleterious	1	deleterious	0,84	low_impact	-1,62	medium_impact	-0,09	high_impact	3,04	0,28	0,8	58,68	8,52	P	0,55	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15336	15336	T	G	MI.9586	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	590	197	L	R	cTc/cGc	-0,73	0	0	benign	0,41	neutral	0,34	neutral	2,84	deleterious	-7,87	deleterious	-4,76	high_impact	5,46	neutral	0,94	neutral	0,33	deleterious	4,15	23,8	0,01	0,35	disease	0,89	disease	0,9	disease	0,71	disease	0,75	5	neutral	0,61	neutral	0,47	neutral	-2	deleterious	0,66	medium_impact	-0,58	medium_impact	0,07	high_impact	3,76	0,19	0,8	58,68	8,52	P	0,6	P	0,99	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15336	15336	T	A	MI.9587	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	590	197	L	H	cTc/cAc	-0,73	0	0	possibly_damaging	0,81	neutral	0,67	neutral	2,83	deleterious	-8,81	deleterious	-5,57	high_impact	5,46	neutral	0,93	neutral	0,33	deleterious	4,1	23,7	0,03	0,35	disease	0,93	disease	0,85	disease	0,66	disease	0,77	5	neutral	0,78	neutral	0,43	deleterious	1	deleterious	0,75	low_impact	-1,32	medium_impact	0,39	high_impact	3,76	0,29	0,8	58,68	8,52	P	0,59	P	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15338	15338	C	G	MI.9588	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	592	198	L	V	Cta/Gta	-10,6	0	0	probably_damaging	0,98	neutral	0,46	neutral	3,04	deleterious	-5,3	neutral	-1,88	medium_impact	2,56	neutral	0,95	damaging	0,11	neutral	1,73	14,61	0,27	0,45	neutral	0,34	disease	0,58	neutral	0,37	neutral	0,44	1	neutral	0,98	neutral	0,24	deleterious	1	deleterious	0,7	low_impact	-2,31	medium_impact	0,18	medium_impact	1,13	0,54	0,8	47,37	9,09	N	0,28	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15338	15338	C	A	MI.9589	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	592	198	L	M	Cta/Ata	-10,6	0	0	probably_damaging	1	neutral	0,24	neutral	3,05	deleterious	-5,97	neutral	-1,34	low_impact	1,86	neutral	0,94	damaging	0,11	deleterious	3,61	23,2	0,24	0,45	neutral	0,47	disease	0,58	neutral	0,34	neutral	0,4	2	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,71	low_impact	-3,53	medium_impact	-0,05	medium_impact	0,5	0,47	0,8	47,37	9,09	N	0,35	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8977	8977	A	T	MI.959	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	451	151	I	F	Att/Ttt	-3,34	0	0	probably_damaging	0,99	deleterious	0	neutral	4,28	neutral	-2	deleterious	-3,61	medium_impact	2,63	neutral	0,77	neutral	0,46	deleterious	3,81	23,4	0,38	0,65	neutral	0,28	disease	0,84	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,01	deleterious	5	deleterious	0,76	low_impact	-2,65	low_impact	-1,4	medium_impact	1,16	0,81	0,9	50,44	8,78	N	0,31	N	0,97	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15339	15339	T	G	MI.9590	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	593	198	L	R	cTa/cGa	-0,04	0	0	probably_damaging	1	neutral	0,3	neutral	2,91	deleterious	-7,87	deleterious	-4,28	high_impact	4,67	neutral	0,94	damaging	0,06	deleterious	4,14	23,8	0,01	0,35	disease	0,65	disease	0,9	disease	0,7	disease	0,75	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,02	high_impact	3,05	0,13	0,8	47,37	9,09	N	0,53	P	0,99	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15339	15339	T	A	MI.9591	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	593	198	L	Q	cTa/cAa	-0,04	0	0	probably_damaging	1	neutral	0,26	neutral	2,95	deleterious	-8,09	deleterious	-4,26	high_impact	5,02	neutral	0,93	damaging	0,08	deleterious	4,02	23,6	0,02	0,35	disease	0,67	disease	0,87	disease	0,58	disease	0,68	4	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	-0,02	high_impact	3,36	0,29	0,8	47,37	9,09	P	0,62	P	0,98	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15339	15339	T	C	MI.9592	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	593	198	L	P	cTa/cCa	-0,04	0	0	probably_damaging	1	neutral	0,2	neutral	2,9	deleterious	-8,49	deleterious	-4,96	high_impact	5,02	neutral	0,93	damaging	0,06	deleterious	3,87	23,5	0,01	0,35	disease	0,73	disease	0,87	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,1	high_impact	3,36	0,32	0,8	47,37	9,09	P	0,62	P	0,99	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15341	15341	T	A	MI.9593	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	595	199	F	I	Ttc/Atc	-4,86	0	0,01	probably_damaging	1	neutral	0,46	neutral	3,22	deleterious	-6,35	deleterious	-4,79	high_impact	3,99	neutral	0,85	neutral	0,48	deleterious	4,18	23,8	0,11	0,4	neutral	0,3	disease	0,81	disease	0,63	disease	0,68	4	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,74	low_impact	-3,53	medium_impact	0,18	high_impact	2,43	0,35	0,8	57,11	8,71	N	0,36	N	0,97	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15341	15341	T	C	MI.9594	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	595	199	F	L	Ttc/Ctc	-4,86	0	0,01	probably_damaging	0,99	neutral	0,92	neutral	3,58	deleterious	-5,21	deleterious	-4,75	medium_impact	2,07	neutral	0,84	neutral	0,45	deleterious	3,6	23,2	0,11	0,4	neutral	0,28	disease	0,77	neutral	0,43	neutral	0,47	1	deleterious	0,99	neutral	0,47	deleterious	1	deleterious	0,72	low_impact	-2,59	medium_impact	0,8	medium_impact	0,69	0,52	0,8	57,11	8,71	N	0,2	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15341	15341	T	G	MI.9595	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	595	199	F	V	Ttc/Gtc	-4,86	0	0,01	probably_damaging	1	neutral	0,5	neutral	3,18	deleterious	-6,39	deleterious	-5,61	high_impact	4,18	neutral	0,85	neutral	0,5	deleterious	3,95	23,6	0,06	0,35	neutral	0,32	disease	0,82	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,73	low_impact	-3,53	medium_impact	0,22	high_impact	2,6	0,26	0,8	57,11	8,71	N	0,35	N	0,99	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15342	15342	T	A	MI.9596	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	596	199	F	Y	tTc/tAc	7,3	1	0	probably_damaging	0,99	neutral	1	neutral	3,11	deleterious	-5	neutral	-2,41	medium_impact	2,93	neutral	0,92	neutral	0,47	deleterious	4,05	23,7	0,17	0,45	disease	0,61	disease	0,78	disease	0,57	disease	0,66	3	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,78	low_impact	-2,59	high_impact	1,85	medium_impact	1,47	0,48	0,8	57,11	8,71	N	0,47	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15342	15342	T	G	MI.9597	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	596	199	F	C	tTc/tGc	7,3	1	0	probably_damaging	1	neutral	0,21	neutral	3,08	deleterious	-8,87	deleterious	-6,45	high_impact	4,06	neutral	0,84	neutral	0,4	deleterious	4,06	23,7	0,03	0,35	disease	0,72	disease	0,85	disease	0,58	disease	0,69	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	-0,09	high_impact	2,49	0,21	0,8	57,11	8,71	N	0,51	P	0,99	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15342	15342	T	C	MI.9598	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	596	199	F	S	tTc/tCc	7,3	1	0	probably_damaging	1	neutral	0,47	neutral	3,11	deleterious	-7,39	deleterious	-6,46	medium_impact	3,48	neutral	0,84	neutral	0,44	deleterious	4,21	23,9	0,03	0,35	neutral	0,43	disease	0,85	disease	0,62	disease	0,71	4	deleterious	1	neutral	0,24	deleterious	1	deleterious	0,79	low_impact	-3,53	medium_impact	0,19	medium_impact	1,97	0,22	0,8	57,11	8,71	N	0,47	N	0,99	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15343	15343	C	A	MI.9599	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	597	199	F	L	ttC/ttA	5,69	1	0	probably_damaging	0,99	neutral	0,92	neutral	3,58	deleterious	-5,21	deleterious	-4,75	medium_impact	2,07	neutral	0,84	neutral	0,45	deleterious	4,23	23,9	0,11	0,4	neutral	0,28	disease	0,77	neutral	0,43	neutral	0,47	1	deleterious	0,99	neutral	0,47	deleterious	1	deleterious	0,72	low_impact	-2,59	medium_impact	0,8	medium_impact	0,69	0,52	0,8	57,11	8,71	N	0,4	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8569	8569	C	G	MI.96	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	43	15	L	V	Cta/Gta	-2,88	0	0	probably_damaging	0,99	neutral	0,08	neutral	4,52	neutral	-1,34	neutral	-1,78	medium_impact	2,33	neutral	0,93	neutral	0,76	deleterious	3,11	22,5	0,4	0,65	disease	0,52	disease	0,63	disease	0,66	disease	0,63	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,74	low_impact	-2,65	medium_impact	-0,31	medium_impact	0,9	0,66	0,9	11,5	26,27	N	0,4	N	0,33	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8977	8977	A	G	MI.960	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	451	151	I	V	Att/Gtt	-3,34	0	0	probably_damaging	0,93	neutral	0,12	neutral	4,32	neutral	-0,2	neutral	-0,9	medium_impact	2,25	neutral	0,79	neutral	0,49	deleterious	3,09	22,5	0,59	0,7	neutral	0,47	disease	0,52	neutral	0,48	neutral	0,44	1	neutral	0,97	neutral	0,1	deleterious	1	deleterious	0,67	low_impact	-1,82	medium_impact	-0,2	medium_impact	0,83	0,57	0,9	50,44	8,78	N	0,37	N	0,77	disease_causing	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15343	15343	C	G	MI.9600	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	597	199	F	L	ttC/ttG	5,69	1	0	probably_damaging	0,99	neutral	0,92	neutral	3,58	deleterious	-5,21	deleterious	-4,75	medium_impact	2,07	neutral	0,84	neutral	0,45	deleterious	3,95	23,6	0,11	0,4	neutral	0,28	disease	0,77	neutral	0,43	neutral	0,47	1	deleterious	0,99	neutral	0,47	deleterious	1	deleterious	0,72	low_impact	-2,59	medium_impact	0,8	medium_impact	0,69	0,52	0,8	57,11	8,71	N	0,4	N	0,92	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15344	15344	T	A	MI.9601	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	598	200	L	M	Ttg/Atg	-2,57	0	0	probably_damaging	1	neutral	0,26	neutral	2,97	deleterious	-6,82	neutral	-1,64	high_impact	5,62	neutral	0,94	damaging	0,11	deleterious	3,44	23	0,19	0,45	disease	0,71	disease	0,59	disease	0,63	disease	0,65	3	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	-0,02	high_impact	3,91	0,49	0,8	58,16	8,76	P	0,64	P	0,94	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15344	15344	T	G	MI.9602	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	598	200	L	V	Ttg/Gtg	-2,57	0	0	probably_damaging	0,99	neutral	0,58	neutral	3,13	deleterious	-6,32	neutral	-2,44	high_impact	4,58	neutral	0,95	damaging	0,11	deleterious	2,99	22,2	0,17	0,45	neutral	0,44	disease	0,54	disease	0,65	disease	0,65	3	deleterious	0,99	neutral	0,3	deleterious	2	deleterious	0,73	low_impact	-2,59	medium_impact	0,3	high_impact	2,97	0,53	0,8	58,16	8,76	N	0,35	N	0,88	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15345	15345	T	G	MI.9603	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	599	200	L	W	tTg/tGg	0,41	0,05	0	probably_damaging	1	neutral	0,19	neutral	2,95	deleterious	-10,07	deleterious	-4,93	high_impact	5,62	neutral	0,95	damaging	0,09	deleterious	3,78	23,4	0,04	0,35	disease	0,95	disease	0,71	disease	0,68	disease	0,8	6	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,12	high_impact	3,91	0,13	0,8	58,16	8,76	P	0,61	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15345	15345	T	C	MI.9604	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	599	200	L	S	tTg/tCg	0,41	0,05	0	probably_damaging	1	neutral	0,64	neutral	2,95	deleterious	-8,7	deleterious	-4,92	high_impact	5,07	neutral	0,95	damaging	0,1	deleterious	3,72	23,3	0,04	0,35	disease	0,84	disease	0,75	disease	0,66	disease	0,73	5	deleterious	1	neutral	0,32	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,36	high_impact	3,41	0,19	0,8	58,16	8,76	P	0,63	P	0,97	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15346	15346	G	T	MI.9605	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	600	200	L	F	ttG/ttT	7,3	0,95	0,08	probably_damaging	1	neutral	0,8	neutral	2,99	deleterious	-7,01	deleterious	-3,28	high_impact	4,38	neutral	0,96	damaging	0,1	deleterious	3,57	23,1	0,12	0,4	disease	0,75	disease	0,69	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,4	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,55	high_impact	2,78	0,42	0,8	58,16	8,76	N	0,48	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15346	15346	G	C	MI.9606	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	600	200	L	F	ttG/ttC	7,3	0,95	0,08	probably_damaging	1	neutral	0,8	neutral	2,99	deleterious	-7,01	deleterious	-3,28	high_impact	4,38	neutral	0,96	damaging	0,1	deleterious	3,42	23	0,12	0,4	disease	0,75	disease	0,69	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,4	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,55	high_impact	2,78	0,42	0,8	58,16	8,76	N	0,47	N	0,97	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15347	15347	C	A	MI.9607	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	601	201	H	N	Cac/Aac	-15,18	0	0	probably_damaging	0,99	neutral	0,35	neutral	3,06	deleterious	-8,9	deleterious	-5,75	high_impact	5,07	neutral	0,86	damaging	0,13	deleterious	2,28	18,06	0,15	0,45	neutral	0,43	disease	0,78	disease	0,77	disease	0,72	4	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,77	low_impact	-2,59	medium_impact	0,08	high_impact	3,41	0,2	0,8	58,68	8,69	P	0,59	P	0,97	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15347	15347	C	T	MI.9608	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	601	201	H	Y	Cac/Tac	-15,18	0	0	probably_damaging	0,99	neutral	1	neutral	3	deleterious	-8,28	deleterious	-4,93	high_impact	5,07	neutral	0,87	damaging	0,13	deleterious	2,11	16,93	0,08	0,35	disease	0,85	disease	0,82	disease	0,79	disease	0,75	5	deleterious	0,99	deleterious	0,51	deleterious	2	deleterious	0,84	low_impact	-2,59	high_impact	1,85	high_impact	3,41	0,2	0,8	58,68	8,69	P	0,64	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15347	15347	C	G	MI.9609	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	601	201	H	D	Cac/Gac	-15,18	0	0	probably_damaging	1	neutral	0,24	neutral	3,04	deleterious	-8,53	deleterious	-7,4	high_impact	5,28	neutral	0,84	damaging	0,11	deleterious	3,6	23,2	0,05	0,35	disease	0,69	disease	0,8	disease	0,84	disease	0,75	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,05	high_impact	3,6	0,15	0,8	58,68	8,69	P	0,57	P	0,98	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8977	8977	A	C	MI.961	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	451	151	I	L	Att/Ctt	-3,34	0	0	probably_damaging	0,93	deleterious	0,01	neutral	4,35	neutral	-0,26	neutral	-1,8	medium_impact	3,02	neutral	0,79	neutral	0,46	deleterious	3,78	23,4	0,35	0,65	disease	0,51	disease	0,73	disease	0,55	disease	0,63	3	deleterious	1	neutral	0,04	deleterious	5	deleterious	0,7	low_impact	-1,82	medium_impact	-0,84	medium_impact	1,49	0,65	0,9	50,44	8,78	N	0,31	N	0,83	disease_causing	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15348	15348	A	G	MI.9610	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	602	201	H	R	cAc/cGc	5,46	1	0	probably_damaging	0,99	neutral	0,37	neutral	3,07	deleterious	-8,43	deleterious	-6,57	high_impact	4,72	neutral	0,87	damaging	0,09	neutral	1,44	13,01	0,06	0,35	neutral	0,35	disease	0,82	disease	0,8	disease	0,72	4	deleterious	0,99	neutral	0,19	deleterious	2	deleterious	0,78	low_impact	-2,59	medium_impact	0,1	high_impact	3,09	0,31	0,8	58,68	8,69	P	0,62	P	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15348	15348	A	C	MI.9611	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	602	201	H	P	cAc/cCc	5,46	1	0	probably_damaging	1	neutral	0,23	neutral	3,01	deleterious	-9,53	deleterious	-8,22	high_impact	4,82	neutral	0,88	damaging	0,08	deleterious	3,02	22,3	0,03	0,35	disease	0,81	disease	0,85	disease	0,85	disease	0,77	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,06	high_impact	3,18	0,11	0,8	58,68	8,69	P	0,62	P	0,99	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15348	15348	A	T	MI.9612	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	602	201	H	L	cAc/cTc	5,46	1	0	probably_damaging	0,99	neutral	0,86	neutral	3,09	deleterious	-8,79	deleterious	-9,04	high_impact	5,07	neutral	0,88	damaging	0,11	deleterious	2,31	18,25	0,04	0,35	disease	0,73	disease	0,87	disease	0,76	disease	0,73	5	deleterious	0,99	neutral	0,44	deleterious	2	deleterious	0,83	low_impact	-2,59	medium_impact	0,65	high_impact	3,41	0,12	0,8	58,68	8,69	P	0,67	P	0,92	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15349	15349	C	A	MI.9613	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	603	201	H	Q	caC/caA	6,84	1	0	probably_damaging	1	neutral	0,32	neutral	3,11	deleterious	-8,97	deleterious	-6,57	high_impact	4,65	neutral	0,91	damaging	0,12	deleterious	2,32	18,27	0,08	0,35	disease	0,57	disease	0,81	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	0,05	high_impact	3,03	0,25	0,8	58,68	8,69	P	0,6	P	0,94	polymorphism	1	0,18	rs527236201	Likely pathogenic,Likely pathogenic	Familial_cancer_of_breast,Familial_cancer_of_breast	RCV000133423.1,RCV000133424.1	MedGen:OMIM:Orphanet:SNOMED_CT,MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	15349	15349	C	G	MI.9614	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	603	201	H	Q	caC/caG	6,84	1	0	probably_damaging	1	neutral	0,32	neutral	3,11	deleterious	-8,97	deleterious	-6,57	high_impact	4,65	neutral	0,91	damaging	0,12	deleterious	1,99	16,14	0,08	0,35	disease	0,57	disease	0,81	disease	0,77	disease	0,74	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	0,05	high_impact	3,03	0,25	0,8	58,68	8,69	P	0,59	P	0,94	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15350	15350	G	C	MI.9615	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	604	202	E	Q	Gaa/Caa	-0,5	0,46	0	probably_damaging	0,99	neutral	0,45	neutral	3,19	deleterious	-4,19	neutral	-2,05	low_impact	1,36	neutral	0,92	damaging	0,11	neutral	1,79	14,9	0,26	0,45	neutral	0,24	disease	0,67	neutral	0,21	neutral	0,36	3	deleterious	0,99	neutral	0,23	neutral	-2	deleterious	0,72	low_impact	-2,59	medium_impact	0,18	medium_impact	0,04	0,26	0,8	56,84	8,3	N	0,3	N	0,94	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15350	15350	G	A	MI.9616	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	604	202	E	K	Gaa/Aaa	-0,5	0,46	0	probably_damaging	0,99	neutral	0,54	neutral	3,33	deleterious	-3,7	deleterious	-3,07	medium_impact	2,8	neutral	0,96	damaging	0,09	deleterious	2,94	22	0,1	0,4	neutral	0,22	disease	0,89	neutral	0,5	disease	0,68	4	deleterious	0,99	neutral	0,28	deleterious	1	deleterious	0,79	low_impact	-2,59	medium_impact	0,26	medium_impact	1,35	0,48	0,8	56,84	8,3	N	0,23	N	1	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15351	15351	A	C	MI.9617	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	605	202	E	A	gAa/gCa	4,08	1	0	probably_damaging	0,99	neutral	0,71	neutral	3,16	deleterious	-3,71	deleterious	-4,69	high_impact	4,18	neutral	0,94	damaging	0,15	deleterious	3,35	22,9	0,09	0,35	neutral	0,31	disease	0,72	disease	0,58	disease	0,63	3	deleterious	0,99	neutral	0,36	deleterious	2	deleterious	0,75	low_impact	-2,59	medium_impact	0,43	high_impact	2,6	0,17	0,8	56,84	8,3	N	0,42	N	0,83	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15351	15351	A	T	MI.9618	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	605	202	E	V	gAa/gTa	4,08	1	0	probably_damaging	0,99	neutral	0,57	neutral	3,08	neutral	-1,47	deleterious	-5,52	high_impact	3,6	neutral	0,93	damaging	0,12	deleterious	2,68	20,7	0,05	0,35	neutral	0,42	disease	0,86	disease	0,61	disease	0,68	4	deleterious	0,99	neutral	0,29	deleterious	2	deleterious	0,78	low_impact	-2,59	medium_impact	0,29	high_impact	2,08	0,2	0,8	56,84	8,3	N	0,39	N	0,89	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15351	15351	A	G	MI.9619	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	605	202	E	G	gAa/gGa	4,08	1	0	probably_damaging	1	neutral	0,46	neutral	3,08	deleterious	-4,68	deleterious	-5,49	high_impact	3,76	neutral	0,94	damaging	0,14	deleterious	4,06	23,7	0,07	0,35	disease	0,53	disease	0,75	disease	0,59	disease	0,63	3	deleterious	0,99	neutral	0,23	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	0,18	high_impact	2,22	0,14	0,8	56,84	8,3	N	0,47	N	0,77	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8978	8978	T	A	MI.962	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	452	151	I	N	aTt/aAt	8,69	1	0	probably_damaging	1	deleterious	0	neutral	4,23	deleterious	-3,84	deleterious	-6,31	high_impact	3,88	neutral	0,82	neutral	0,49	deleterious	4,46	24,2	0,31	0,65	disease	0,84	disease	0,85	disease	0,69	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,6	low_impact	-1,4	high_impact	2,23	0,7	0,9	50,44	8,78	P	0,53	P	1	disease_causing	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15352	15352	A	T	MI.9620	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	606	202	E	D	gaA/gaT	6,84	1	0	probably_damaging	0,95	neutral	0,38	neutral	3,11	deleterious	-3,75	neutral	-2,31	medium_impact	2,48	neutral	0,88	damaging	0,26	deleterious	1,93	15,77	0,24	0,45	neutral	0,42	disease	0,73	neutral	0,41	neutral	0,47	1	neutral	0,96	neutral	0,22	deleterious	1	deleterious	0,73	low_impact	-1,92	medium_impact	0,11	medium_impact	1,06	0,29	0,8	56,84	8,3	N	0,54	P	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15352	15352	A	C	MI.9621	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	606	202	E	D	gaA/gaC	6,84	1	0	probably_damaging	0,95	neutral	0,38	neutral	3,11	deleterious	-3,75	neutral	-2,31	medium_impact	2,48	neutral	0,88	damaging	0,26	deleterious	1,83	15,19	0,24	0,45	neutral	0,42	disease	0,73	neutral	0,41	neutral	0,47	1	neutral	0,96	neutral	0,22	deleterious	1	deleterious	0,73	low_impact	-1,92	medium_impact	0,11	medium_impact	1,06	0,29	0,8	56,84	8,3	N	0,53	P	0,91	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15353	15353	A	C	MI.9622	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	607	203	T	P	Acg/Ccg	1,33	1	0	possibly_damaging	0,66	neutral	0,26	neutral	3,08	deleterious	-5,74	deleterious	-4,66	high_impact	4,47	neutral	0,95	damaging	0,06	deleterious	3,24	22,8	0,06	0,35	neutral	0,43	disease	0,78	disease	0,59	disease	0,66	3	neutral	0,78	neutral	0,3	deleterious	1	deleterious	0,67	medium_impact	-1	medium_impact	-0,02	high_impact	2,87	0,19	0,8	58,68	8,17	N	0,47	N	0,96	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15353	15353	A	G	MI.9623	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	607	203	T	A	Acg/Gcg	1,33	1	0	benign	0,01	neutral	0,64	neutral	3,14	deleterious	-3,48	deleterious	-3,79	medium_impact	3,48	neutral	0,98	damaging	0,16	neutral	1,64	14,06	0,23	0,45	neutral	0,29	disease	0,56	disease	0,59	disease	0,62	2	neutral	0,35	deleterious	0,82	neutral	-3	neutral	0,17	medium_impact	1,13	medium_impact	0,36	medium_impact	1,97	0,24	0,8	58,68	8,17	N	0,41	N	0,6	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15353	15353	A	T	MI.9624	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	607	203	T	S	Acg/Tcg	1,33	1	0	benign	0,12	neutral	0,55	neutral	3,16	neutral	-1,49	deleterious	-2,87	medium_impact	2,04	neutral	0,97	neutral	0,31	neutral	1,47	13,14	0,38	0,5	neutral	0,3	neutral	0,5	neutral	0,33	neutral	0,33	3	neutral	0,36	deleterious	0,72	neutral	-3	neutral	0,23	medium_impact	0,08	medium_impact	0,27	medium_impact	0,66	0,35	0,8	58,68	8,17	N	0,39	N	0,79	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15354	15354	C	T	MI.9625	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	608	203	T	M	aCg/aTg	2,48	1	0	probably_damaging	0,93	neutral	0,24	neutral	3,05	deleterious	-6,75	deleterious	-4,65	high_impact	3,92	neutral	0,94	damaging	0,09	deleterious	3,97	23,6	0,12	0,4	disease	0,64	disease	0,75	disease	0,54	disease	0,63	3	neutral	0,95	neutral	0,16	deleterious	2	deleterious	0,72	low_impact	-1,78	medium_impact	-0,05	high_impact	2,37	0,27	0,8	58,68	8,17	N	0,43	N	0,96	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15354	15354	C	A	MI.9626	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	608	203	T	K	aCg/aAg	2,48	1	0	benign	0,26	neutral	0,46	neutral	3,16	deleterious	-5,37	deleterious	-4,57	medium_impact	2,68	neutral	0,96	damaging	0,07	deleterious	4,15	23,8	0,11	0,4	neutral	0,23	disease	0,82	neutral	0,44	disease	0,52	0	neutral	0,44	deleterious	0,6	neutral	-3	deleterious	0,53	medium_impact	-0,31	medium_impact	0,18	medium_impact	1,24	0,28	0,8	58,68	8,17	N	0,46	N	0,97	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15356	15356	G	C	MI.9627	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	610	204	G	R	Gga/Cga	-2,34	0	0	probably_damaging	1	neutral	0,35	neutral	2,83	deleterious	-11,34	deleterious	-6,58	high_impact	5,08	neutral	0,79	damaging	0,03	deleterious	3,99	23,6	0,02	0,35	disease	0,86	disease	0,87	disease	0,81	disease	0,7	4	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	0,08	high_impact	3,42	0,67	0,85	57,89	8,82	P	0,61	P	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15356	15356	G	T	MI.9628	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	610	204	G	W	Gga/Tga	-2,34	0	0	probably_damaging	1	neutral	0,18	neutral	2,78	deleterious	-13,3	deleterious	-6,58	high_impact	5,28	neutral	0,86	damaging	0,05	deleterious	4,46	24,2	0,03	0,35	disease	0,98	disease	0,88	disease	0,8	disease	0,79	6	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,89	low_impact	-3,53	medium_impact	-0,14	high_impact	3,6	0,11	0,8	57,89	8,82	P	0,54	P	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15357	15357	G	A	MI.9629	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	611	204	G	E	gGa/gAa	5,92	1	0	probably_damaging	1	neutral	0,3	neutral	2,84	deleterious	-10,87	deleterious	-6,58	high_impact	5,28	neutral	0,72	damaging	0,04	deleterious	3,9	23,5	0,02	0,35	disease	0,53	disease	0,87	disease	0,81	disease	0,72	4	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,02	high_impact	3,6	0,25	0,8	57,89	8,82	P	0,63	P	1	polymorphism	1	0,27	.	.	.	.	.	.	COSM1155591	.	.	.	.	.	.	.	.
chrM	8978	8978	T	G	MI.963	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	452	151	I	S	aTt/aGt	8,69	1	0	probably_damaging	0,99	neutral	0,18	neutral	4,35	neutral	-0,72	deleterious	-5,37	medium_impact	2,21	neutral	0,82	neutral	0,6	deleterious	4,32	24	0,33	0,65	neutral	0,44	disease	0,87	disease	0,64	disease	0,66	3	deleterious	0,99	neutral	0,1	deleterious	1	deleterious	0,8	low_impact	-2,65	medium_impact	-0,08	medium_impact	0,8	0,59	0,9	50,44	8,78	N	0,47	N	0,98	disease_causing	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15357	15357	G	T	MI.9630	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	611	204	G	V	gGa/gTa	5,92	1	0	probably_damaging	1	neutral	0,52	neutral	2,79	deleterious	-11,21	deleterious	-7,4	high_impact	5,62	neutral	0,81	damaging	0,06	deleterious	3,88	23,5	0,02	0,35	disease	0,9	disease	0,85	disease	0,76	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,24	high_impact	3,91	0,13	0,8	57,89	8,82	P	0,65	P	1	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15357	15357	G	C	MI.9631	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	611	204	G	A	gGa/gCa	5,92	1	0	probably_damaging	1	neutral	0,51	neutral	2,84	deleterious	-9,59	deleterious	-4,93	high_impact	5,28	neutral	0,86	damaging	0,07	deleterious	3,15	22,6	0,05	0,35	disease	0,76	disease	0,69	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,23	high_impact	3,6	0,39	0,8	57,89	8,82	P	0,7	P	0,84	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15359	15359	T	A	MI.9632	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	613	205	S	T	Tca/Aca	-2,8	0	0	probably_damaging	0,96	neutral	0,47	neutral	3,09	deleterious	-7,21	neutral	-2,47	high_impact	4,92	neutral	0,94	damaging	0,1	deleterious	2,02	16,31	0,22	0,45	disease	0,56	disease	0,69	disease	0,6	disease	0,65	3	neutral	0,96	neutral	0,26	deleterious	2	deleterious	0,74	low_impact	-2,02	medium_impact	0,19	high_impact	3,27	0,47	0,8	58,16	8,73	P	0,62	P	0,7	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15359	15359	T	G	MI.9633	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	613	205	S	A	Tca/Gca	-2,8	0	0	probably_damaging	0,98	neutral	0,5	neutral	3,08	deleterious	-6,37	neutral	-2,47	high_impact	3,87	neutral	0,96	damaging	0,14	deleterious	1,99	16,13	0,25	0,45	disease	0,51	disease	0,54	disease	0,59	disease	0,54	1	neutral	0,98	neutral	0,26	deleterious	2	deleterious	0,7	low_impact	-2,31	medium_impact	0,22	high_impact	2,32	0,36	0,8	58,16	8,73	N	0,32	N	0,46	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15359	15359	T	C	MI.9634	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	613	205	S	P	Tca/Cca	-2,8	0	0	probably_damaging	1	neutral	0,26	neutral	3,05	deleterious	-8,5	deleterious	-4,11	high_impact	4,72	neutral	0,95	damaging	0,04	deleterious	3,64	23,2	0,04	0,35	disease	0,79	disease	0,78	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	-0,02	high_impact	3,09	0,09	0,8	58,16	8,73	P	0,64	P	1	polymorphism	1	0,18	.	.	.	.	.	.	COSM1155593	.	.	.	.	.	.	.	.
chrM	15360	15360	C	T	MI.9635	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	614	205	S	L	tCa/tTa	7,3	1	0	probably_damaging	1	neutral	0,76	neutral	3,09	deleterious	-8,69	deleterious	-4,93	high_impact	5,07	neutral	0,95	damaging	0,06	deleterious	4,44	24,2	0,04	0,35	neutral	0,34	disease	0,82	disease	0,7	disease	0,7	4	deleterious	1	neutral	0,38	deleterious	2	deleterious	0,73	low_impact	-3,53	medium_impact	0,49	high_impact	3,41	0,4	0,8	58,16	8,73	P	0,65	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15360	15360	C	G	MI.9636	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	614	205	S	W	tCa/tGa	7,3	1	0	probably_damaging	1	neutral	0,18	neutral	2,99	deleterious	-11,43	deleterious	-5,76	high_impact	5,62	neutral	0,96	damaging	0,09	deleterious	4,3	24	0,05	0,35	disease	0,87	disease	0,85	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,14	high_impact	3,91	0,11	0,8	58,16	8,73	P	0,63	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15362	15362	A	C	MI.9637	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	616	206	N	H	Aac/Cac	-6,47	0	0	probably_damaging	1	neutral	0,22	neutral	2,98	deleterious	-6,86	deleterious	-3,88	high_impact	4,49	neutral	0,93	damaging	0,24	deleterious	3,12	22,6	0,33	0,5	disease	0,79	disease	0,79	disease	0,72	disease	0,73	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	-0,08	high_impact	2,88	0,12	0,8	40,53	8,41	N	0,49	N	0,98	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15362	15362	A	T	MI.9638	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	616	206	N	Y	Aac/Tac	-6,47	0	0	probably_damaging	1	neutral	0,19	neutral	3,02	deleterious	-7,49	deleterious	-6,16	high_impact	5,18	neutral	0,94	neutral	0,31	deleterious	3,79	23,4	0,08	0,35	disease	0,86	disease	0,85	disease	0,72	disease	0,75	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	-0,12	high_impact	3,51	0,13	0,8	40,53	8,41	P	0,63	P	1	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15362	15362	A	G	MI.9639	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	616	206	N	D	Aac/Gac	-6,47	0	0	probably_damaging	1	neutral	0,52	neutral	3	deleterious	-4,82	deleterious	-3,81	high_impact	4,83	neutral	0,92	neutral	0,33	deleterious	3,76	23,4	0,54	0,6	disease	0,53	disease	0,73	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,74	low_impact	-3,53	medium_impact	0,24	high_impact	3,19	0,24	0,8	40,53	8,41	P	0,64	P	0,95	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8978	8978	T	C	MI.964	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	452	151	I	T	aTt/aCt	8,69	1	0	probably_damaging	0,99	neutral	0,08	neutral	4,36	neutral	-1,11	deleterious	-4,46	medium_impact	2,84	neutral	0,82	neutral	0,5	deleterious	3,38	23	0,51	0,65	neutral	0,4	disease	0,75	disease	0,63	disease	0,66	3	deleterious	1	neutral	0,05	deleterious	1	deleterious	0,77	low_impact	-2,65	medium_impact	-0,31	medium_impact	1,34	0,69	0,9	50,44	8,78	P	0,49	N	0,99	disease_causing	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15363	15363	A	T	MI.9640	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	617	206	N	I	aAc/aTc	6,61	1	0	probably_damaging	1	neutral	0,18	neutral	3,02	deleterious	-7,07	deleterious	-6,88	high_impact	5,18	neutral	0,94	neutral	0,39	deleterious	3,84	23,4	0,09	0,35	disease	0,82	disease	0,87	disease	0,67	disease	0,72	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,14	high_impact	3,51	0,12	0,8	40,53	8,41	P	0,69	P	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15363	15363	A	G	MI.9641	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	617	206	N	S	aAc/aGc	6,61	1	0	probably_damaging	0,99	neutral	0,99	neutral	3,1	neutral	-2,48	deleterious	-3,59	low_impact	0,88	neutral	0,96	neutral	0,69	deleterious	2,66	20,6	0,42	0,55	neutral	0,29	disease	0,65	neutral	0,42	neutral	0,43	1	deleterious	0,99	deleterious	0,5	neutral	-2	deleterious	0,71	low_impact	-2,59	medium_impact	1,3	medium_impact	-0,39	0,21	0,8	40,53	8,41	N	0,44	N	0,86	polymorphism	1	0,11	rs527236182	Likely pathogenic	Neoplasm_of_ovary	RCV000133426.1	Gene:MedGen:OMIM:SNOMED_CT	.	.	.	3,57	.	.	.	.	.	.
chrM	15363	15363	A	C	MI.9642	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	617	206	N	T	aAc/aCc	6,61	1	0	probably_damaging	1	neutral	0,43	neutral	3,11	deleterious	-5,19	deleterious	-4,31	medium_impact	2,73	neutral	0,97	neutral	0,41	deleterious	3,31	22,9	0,26	0,45	neutral	0,32	disease	0,74	disease	0,56	neutral	0,48	0	deleterious	1	neutral	0,22	deleterious	1	deleterious	0,72	low_impact	-3,53	medium_impact	0,16	medium_impact	1,29	0,25	0,8	40,53	8,41	N	0,52	P	0,94	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15364	15364	C	A	MI.9643	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	618	206	N	K	aaC/aaA	4,54	1	0	probably_damaging	1	neutral	0,58	neutral	3,03	deleterious	-5,37	deleterious	-4,56	high_impact	4,03	neutral	0,94	damaging	0,26	deleterious	4,43	24,2	0,38	0,5	disease	0,59	disease	0,8	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,3	high_impact	2,47	0,32	0,8	40,53	8,41	N	0,47	N	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15364	15364	C	G	MI.9644	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	618	206	N	K	aaC/aaG	4,54	1	0	probably_damaging	1	neutral	0,58	neutral	3,03	deleterious	-5,37	deleterious	-4,56	high_impact	4,03	neutral	0,94	damaging	0,26	deleterious	3,97	23,6	0,38	0,5	disease	0,59	disease	0,8	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,3	high_impact	2,47	0,32	0,8	40,53	8,41	N	0,47	N	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15365	15365	A	C	MI.9645	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	619	207	N	H	Aac/Cac	-3,26	0	0	probably_damaging	1	neutral	0,45	neutral	3,02	deleterious	-7,06	deleterious	-4,09	high_impact	5,61	neutral	0,93	damaging	0,08	deleterious	2,98	22,2	0,18	0,45	disease	0,88	disease	0,78	disease	0,81	disease	0,74	5	deleterious	1	neutral	0,23	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,18	high_impact	3,9	0,18	0,8	56,84	8,75	P	0,73	P	0,98	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15365	15365	A	T	MI.9646	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	619	207	N	Y	Aac/Tac	-3,26	0	0	probably_damaging	1	neutral	0,6	neutral	3,01	deleterious	-6,37	deleterious	-6,55	high_impact	5,26	neutral	0,94	damaging	0,09	deleterious	3,55	23,1	0,06	0,35	disease	0,93	disease	0,84	disease	0,8	disease	0,77	5	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,32	high_impact	3,58	0,15	0,8	56,84	8,75	P	0,65	P	1	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15365	15365	A	G	MI.9647	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	619	207	N	D	Aac/Gac	-3,26	0	0	probably_damaging	1	neutral	0,28	neutral	3,05	deleterious	-6,41	deleterious	-4,09	high_impact	5,06	neutral	0,93	damaging	0,1	deleterious	3,59	23,2	0,33	0,5	neutral	0,48	disease	0,71	disease	0,81	disease	0,69	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,75	low_impact	-3,53	medium_impact	0	high_impact	3,4	0,23	0,8	56,84	8,75	P	0,68	P	0,95	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15366	15366	A	C	MI.9648	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	620	207	N	T	aAc/aCc	8,44	1	0	probably_damaging	1	neutral	0,38	neutral	3,08	deleterious	-4,91	deleterious	-4,9	high_impact	4,71	neutral	0,96	damaging	0,13	deleterious	3,83	23,4	0,14	0,4	disease	0,8	disease	0,79	disease	0,79	disease	0,74	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,11	high_impact	3,08	0,21	0,8	56,84	8,75	P	0,75	P	0,94	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15366	15366	A	T	MI.9649	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	620	207	N	I	aAc/aTc	8,44	1	0	probably_damaging	1	neutral	0,38	neutral	3,02	neutral	-2,47	deleterious	-7,37	high_impact	5,61	neutral	0,94	damaging	0,11	deleterious	4,49	24,3	0,07	0,35	disease	0,93	disease	0,86	disease	0,78	disease	0,74	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,11	high_impact	3,9	0,09	0,8	56,84	8,75	P	0,75	P	1	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8979	8979	T	A	MI.965	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	453	151	I	M	atT/atA	7,53	1	0	probably_damaging	1	neutral	0,05	neutral	4,25	neutral	-2,09	deleterious	-2,71	medium_impact	2,29	neutral	0,85	neutral	0,6	deleterious	3,69	23,3	0,52	0,65	disease	0,73	disease	0,64	neutral	0,45	neutral	0,49	0	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	-0,43	medium_impact	0,87	0,83	0,9	50,44	8,78	P	0,53	P	0,75	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15366	15366	A	G	MI.9650	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	620	207	N	S	aAc/aGc	8,44	1	0	probably_damaging	0,99	neutral	0,52	neutral	3,08	deleterious	-5,2	deleterious	-4,09	high_impact	4,02	neutral	0,93	damaging	0,09	deleterious	3,34	22,9	0,29	0,45	disease	0,6	disease	0,74	disease	0,73	disease	0,7	4	deleterious	0,99	neutral	0,27	deleterious	2	deleterious	0,8	low_impact	-2,59	medium_impact	0,24	high_impact	2,46	0,19	0,8	56,84	8,75	P	0,56	P	0,86	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15367	15367	C	A	MI.9651	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	621	207	N	K	aaC/aaA	6,84	1	0	probably_damaging	1	neutral	0,25	neutral	3,1	deleterious	-5,76	deleterious	-4,91	high_impact	5,26	neutral	0,96	damaging	0,12	deleterious	4,52	24,3	0,18	0,45	disease	0,77	disease	0,78	disease	0,82	disease	0,73	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,04	high_impact	3,58	0,24	0,8	56,84	8,75	P	0,77	P	1	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15367	15367	C	G	MI.9652	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	621	207	N	K	aaC/aaG	6,84	1	0	probably_damaging	1	neutral	0,25	neutral	3,1	deleterious	-5,76	deleterious	-4,91	high_impact	5,26	neutral	0,96	damaging	0,12	deleterious	4,08	23,7	0,18	0,45	disease	0,77	disease	0,78	disease	0,82	disease	0,73	5	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,04	high_impact	3,58	0,24	0,8	56,84	8,75	P	0,77	P	1	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15368	15368	C	T	MI.9653	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	622	208	P	S	Ccc/Tcc	0,41	0,99	0	probably_damaging	1	neutral	0,49	neutral	3,12	deleterious	-6,82	deleterious	-6,56	high_impact	4,42	neutral	0,84	damaging	0,07	deleterious	3,86	23,5	0,1	0,4	disease	0,5	disease	0,77	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,21	high_impact	2,82	0,05	0,8	57,37	8,72	N	0,43	N	0,85	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15368	15368	C	G	MI.9654	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	622	208	P	A	Ccc/Gcc	0,41	0,99	0	probably_damaging	1	neutral	0,49	neutral	2,99	deleterious	-6,66	deleterious	-6,56	high_impact	5,62	neutral	0,87	damaging	0,11	deleterious	3,02	22,3	0,14	0,4	disease	0,58	disease	0,58	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,21	high_impact	3,91	0,66	0,8	57,37	8,72	P	0,6	P	0,82	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15368	15368	C	A	MI.9655	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	622	208	P	T	Ccc/Acc	0,41	0,99	0	probably_damaging	1	neutral	0,44	neutral	2,97	deleterious	-7,25	deleterious	-6,56	high_impact	4,92	neutral	0,82	damaging	0,08	deleterious	3,86	23,5	0,11	0,4	disease	0,66	disease	0,79	disease	0,76	disease	0,71	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,17	high_impact	3,27	0,44	0,8	57,37	8,72	P	0,61	P	0,96	polymorphism	1	0,44	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15369	15369	C	G	MI.9656	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	623	208	P	R	cCc/cGc	7,07	1	0	probably_damaging	1	neutral	0,34	neutral	2,98	deleterious	-7,61	deleterious	-7,38	high_impact	5,07	neutral	0,82	damaging	0,05	deleterious	3,7	23,3	0,05	0,35	disease	0,73	disease	0,81	disease	0,82	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,07	high_impact	3,41	0,23	0,8	57,37	8,72	P	0,69	P	0,81	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15369	15369	C	A	MI.9657	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	623	208	P	H	cCc/cAc	7,07	1	0	probably_damaging	1	neutral	0,57	neutral	2,93	deleterious	-7,29	deleterious	-7,38	high_impact	5,62	neutral	0,84	damaging	0,07	deleterious	4,08	23,7	0,06	0,35	disease	0,84	disease	0,81	disease	0,81	disease	0,72	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,29	high_impact	3,91	0,25	0,8	57,37	8,72	P	0,71	P	0,71	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15369	15369	C	T	MI.9658	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	623	208	P	L	cCc/cTc	7,07	1	0	probably_damaging	1	neutral	0,69	neutral	2,95	deleterious	-6,54	deleterious	-8,2	high_impact	5,07	neutral	0,85	damaging	0,05	deleterious	4,47	24,2	0,08	0,35	disease	0,73	disease	0,79	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,41	high_impact	3,41	0,66	0,8	57,37	8,72	P	0,68	P	1	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15371	15371	C	A	MI.9659	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	625	209	L	M	Cta/Ata	-11,05	0	0	probably_damaging	1	neutral	0,18	neutral	3,08	neutral	-1,13	neutral	-0,4	low_impact	1,58	neutral	0,88	neutral	0,72	deleterious	2,57	19,91	0,27	0,45	disease	0,61	neutral	0,15	neutral	0,22	neutral	0,39	2	deleterious	1	neutral	0,09	neutral	-2	deleterious	0,65	low_impact	-3,53	medium_impact	-0,14	medium_impact	0,24	0,54	0,8	23,42	40,51	N	0,5	N	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8979	8979	T	G	MI.966	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	453	151	I	M	atT/atG	7,53	1	0	probably_damaging	1	neutral	0,05	neutral	4,25	neutral	-2,09	deleterious	-2,71	medium_impact	2,29	neutral	0,85	neutral	0,6	deleterious	3,42	23	0,52	0,65	disease	0,73	disease	0,64	neutral	0,45	neutral	0,49	0	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,76	low_impact	-3,6	medium_impact	-0,43	medium_impact	0,87	0,83	0,9	50,44	8,78	P	0,52	P	0,75	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15371	15371	C	G	MI.9660	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	625	209	L	V	Cta/Gta	-11,05	0	0	probably_damaging	0,99	neutral	0,45	neutral	3,11	neutral	-0,15	neutral	-0,2	medium_impact	2,31	neutral	0,84	neutral	0,68	deleterious	1,81	15,02	0,3	0,45	neutral	0,36	neutral	0,23	neutral	0,25	neutral	0,46	1	deleterious	0,99	neutral	0,23	deleterious	1	deleterious	0,62	low_impact	-2,59	medium_impact	0,18	medium_impact	0,9	0,35	0,8	23,42	40,51	N	0,42	N	0,21	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15372	15372	T	G	MI.9661	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	626	209	L	R	cTa/cGa	-1,19	0	0	probably_damaging	1	neutral	0,57	neutral	3,19	neutral	3,11	neutral	-1,9	high_impact	4,55	neutral	0,84	neutral	0,52	deleterious	4,22	23,9	0,06	0,35	disease	0,7	disease	0,65	disease	0,66	disease	0,71	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	0,29	high_impact	2,94	0,1	0,8	23,42	40,51	N	0,44	N	0,35	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15372	15372	T	A	MI.9662	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	626	209	L	Q	cTa/cAa	-1,19	0	0	probably_damaging	1	neutral	0,62	neutral	3,11	neutral	2,46	neutral	-1,79	high_impact	4,21	neutral	0,84	neutral	0,57	deleterious	4,11	23,7	0,08	0,35	disease	0,72	disease	0,53	disease	0,6	disease	0,67	3	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,74	low_impact	-3,53	medium_impact	0,34	high_impact	2,63	0,17	0,8	23,42	40,51	N	0,33	N	0,27	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15372	15372	T	C	MI.9663	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	626	209	L	P	cTa/cCa	-1,19	0	0	probably_damaging	1	neutral	0,57	neutral	3,15	neutral	-0,68	neutral	-2,13	high_impact	4,55	neutral	0,78	neutral	0,42	deleterious	3,9	23,5	0,06	0,35	disease	0,79	disease	0,71	disease	0,57	disease	0,72	4	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,29	high_impact	2,94	0,19	0,8	23,42	40,51	N	0,37	N	0,5	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15374	15374	G	C	MI.9664	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	628	210	G	R	Gga/Cga	-1,88	0	0	probably_damaging	1	neutral	0,35	neutral	3,24	deleterious	-8,3	deleterious	-6,54	high_impact	4,8	neutral	0,83	damaging	0,04	deleterious	3,96	23,6	0,03	0,35	disease	0,85	disease	0,77	disease	0,78	disease	0,73	5	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,08	high_impact	3,17	0,73	0,85	57,37	8,84	P	0,66	P	0,99	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15374	15374	G	T	MI.9665	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	628	210	G	W	Gga/Tga	-1,88	0	0	probably_damaging	1	neutral	0,18	neutral	3,04	deleterious	-10,75	deleterious	-6,55	high_impact	5,6	neutral	0,84	damaging	0,05	deleterious	4,47	24,2	0,04	0,35	disease	0,59	disease	0,79	disease	0,77	disease	0,71	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	-0,14	high_impact	3,89	0,06	0,8	57,37	8,84	N	0,55	P	1	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15375	15375	G	A	MI.9666	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	629	210	G	E	gGa/gAa	8,9	1	0	probably_damaging	1	neutral	0,27	neutral	3,16	deleterious	-7,63	deleterious	-6,54	high_impact	5,25	neutral	0,82	damaging	0,05	deleterious	3,97	23,6	0,03	0,35	disease	0,85	disease	0,81	disease	0,73	disease	0,69	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	-0,01	high_impact	3,57	0,15	0,8	57,37	8,84	P	0,7	P	1	polymorphism	1	0,41	.	.	.	.	.	.	COSM1138312	.	.	.	.	.	.	.	.
chrM	15375	15375	G	C	MI.9667	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	629	210	G	A	gGa/gCa	8,9	1	0	probably_damaging	1	neutral	0,51	neutral	3,17	deleterious	-5,83	deleterious	-4,9	high_impact	4,91	neutral	0,84	damaging	0,1	deleterious	3,15	22,6	0,06	0,35	disease	0,77	disease	0,56	disease	0,57	disease	0,63	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,23	high_impact	3,26	0,34	0,8	57,37	8,84	P	0,68	P	0,84	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15375	15375	G	T	MI.9668	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	629	210	G	V	gGa/gTa	8,9	1	0	probably_damaging	1	neutral	0,51	neutral	3,11	deleterious	-7,72	deleterious	-7,36	high_impact	5,05	neutral	0,84	damaging	0,07	deleterious	3,82	23,4	0,03	0,35	disease	0,79	disease	0,78	disease	0,72	disease	0,7	4	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,23	high_impact	3,39	0,07	0,8	57,37	8,84	P	0,65	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15377	15377	A	T	MI.9669	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	631	211	I	F	Atc/Ttc	-3,03	0	0	probably_damaging	1	neutral	0,7	neutral	3,15	neutral	-1,55	neutral	-2,23	medium_impact	2,54	neutral	0,85	neutral	0,49	deleterious	3,71	23,3	0,15	0,45	disease	0,52	disease	0,65	neutral	0,3	neutral	0,46	1	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,71	low_impact	-3,53	medium_impact	0,42	medium_impact	1,11	0,51	0,8	18,68	25,12	N	0,19	N	0,76	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8980	8980	C	G	MI.967	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	454	152	Q	E	Caa/Gaa	-0,8	0,05	0	probably_damaging	0,94	deleterious	0	neutral	3,9	neutral	-0,72	neutral	-1,91	medium_impact	2,25	neutral	0,8	neutral	0,44	deleterious	3,19	22,7	0,39	0,65	disease	0,62	disease	0,86	disease	0,62	disease	0,8	6	deleterious	1	neutral	0,03	deleterious	5	deleterious	0,83	low_impact	-1,89	low_impact	-1,4	medium_impact	0,83	0,77	0,9	46,9	8,18	N	0,27	N	0,94	polymorphism	0,68	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15377	15377	A	C	MI.9670	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	631	211	I	L	Atc/Ctc	-3,03	0	0	probably_damaging	0,99	neutral	0,68	neutral	3,23	neutral	3,84	neutral	0,39	neutral_impact	-0,92	neutral	0,94	neutral	0,91	neutral	-0,58	0,14	0,26	0,45	neutral	0,23	neutral	0,1	neutral	0,15	neutral	0,28	4	deleterious	0,99	neutral	0,35	neutral	-2	deleterious	0,44	low_impact	-2,59	medium_impact	0,4	low_impact	-2,03	0,5	0,8	18,68	25,12	N	0,38	N	0,05	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15377	15377	A	G	MI.9671	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	631	211	I	V	Atc/Gtc	-3,03	0	0	probably_damaging	0,96	neutral	0,51	neutral	3,21	neutral	-2,25	neutral	-0,76	low_impact	1,24	neutral	0,88	neutral	0,84	neutral	1,23	11,91	0,49	0,55	neutral	0,18	neutral	0,25	neutral	0,24	neutral	0,44	1	neutral	0,96	neutral	0,28	neutral	-2	deleterious	0,55	low_impact	-2,02	medium_impact	0,23	medium_impact	-0,07	0,49	0,8	18,68	25,12	N	0,35	N	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15378	15378	T	A	MI.9672	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	632	211	I	N	aTc/aAc	-0,96	0	0	probably_damaging	1	neutral	0,33	neutral	3,19	deleterious	-6,74	deleterious	-4,64	medium_impact	2,88	neutral	0,83	neutral	0,47	deleterious	4,65	24,5	0,15	0,4	neutral	0,45	disease	0,76	disease	0,6	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,75	low_impact	-3,53	medium_impact	0,06	medium_impact	1,42	0,15	0,8	18,68	25,12	N	0,32	N	1	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15378	15378	T	C	MI.9673	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	632	211	I	T	aTc/aCc	-0,96	0	0	probably_damaging	1	neutral	0,39	neutral	3,34	deleterious	-4,55	deleterious	-2,97	medium_impact	2,15	neutral	0,82	neutral	0,66	deleterious	3,5	23,1	0,11	0,4	neutral	0,45	disease	0,56	neutral	0,34	neutral	0,47	1	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,72	low_impact	-3,53	medium_impact	0,12	medium_impact	0,76	0,26	0,8	18,68	25,12	N	0,32	N	0,96	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15378	15378	T	G	MI.9674	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	632	211	I	S	aTc/aGc	-0,96	0	0	probably_damaging	1	neutral	0,42	neutral	3,25	deleterious	-5,69	deleterious	-3,81	medium_impact	2,5	neutral	0,84	neutral	0,46	deleterious	4,33	24	0,04	0,35	disease	0,51	disease	0,74	disease	0,62	disease	0,7	4	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,76	low_impact	-3,53	medium_impact	0,15	medium_impact	1,08	0,15	0,8	18,68	25,12	N	0,27	N	0,94	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15379	15379	C	A	MI.9675	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	633	211	I	M	atC/atA	7,3	0,95	0	probably_damaging	1	neutral	0,22	neutral	3,17	neutral	-2,48	neutral	-0,86	low_impact	1,52	neutral	0,89	neutral	0,87	deleterious	2,57	19,9	0,28	0,45	disease	0,52	neutral	0,37	neutral	0,24	neutral	0,4	2	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,67	low_impact	-3,53	medium_impact	-0,08	medium_impact	0,19	0,52	0,8	18,68	25,12	P	0,58	P	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15379	15379	C	G	MI.9676	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	633	211	I	M	atC/atG	7,3	0,95	0	probably_damaging	1	neutral	0,22	neutral	3,17	neutral	-2,48	neutral	-0,86	low_impact	1,52	neutral	0,89	neutral	0,87	deleterious	2,15	17,15	0,28	0,45	disease	0,52	neutral	0,37	neutral	0,24	neutral	0,4	2	deleterious	1	neutral	0,11	neutral	-2	deleterious	0,67	low_impact	-3,53	medium_impact	-0,08	medium_impact	0,19	0,52	0,8	18,68	25,12	P	0,58	P	0,57	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15380	15380	A	T	MI.9677	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	634	212	T	S	Acc/Tcc	-9,22	0	0,01	benign	0,01	neutral	0,42	neutral	3,19	neutral	-1,06	neutral	0,6	neutral_impact	-0,59	neutral	0,96	neutral	0,97	neutral	1,57	13,7	0,57	0,65	neutral	0,2	neutral	0,14	neutral	0,18	neutral	0,3	4	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,09	medium_impact	1,13	medium_impact	0,15	low_impact	-1,73	0,6	0,8	17,11	27,27	N	0,54	P	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15380	15380	A	C	MI.9678	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	634	212	T	P	Acc/Ccc	-9,22	0	0,01	benign	0,01	neutral	0,22	neutral	3,14	neutral	-2,8	neutral	-0,87	neutral_impact	-0,82	neutral	0,97	neutral	0,97	neutral	1,71	14,45	0,16	0,45	disease	0,51	neutral	0,36	neutral	0,2	neutral	0,36	3	neutral	0,78	deleterious	0,61	neutral	-6	neutral	0,17	medium_impact	1,13	medium_impact	-0,08	low_impact	-1,94	0,36	0,8	17,11	27,27	N	0,45	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15380	15380	A	G	MI.9679	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	634	212	T	A	Acc/Gcc	-9,22	0	0,01	benign	0,05	neutral	0,5	neutral	3,19	neutral	-1,08	neutral	-1,21	neutral_impact	0,34	neutral	0,81	neutral	0,8	deleterious	2,06	16,57	0,4	0,5	neutral	0,3	neutral	0,16	neutral	0,36	neutral	0,3	4	neutral	0,45	deleterious	0,73	neutral	-6	neutral	0,1	medium_impact	0,46	medium_impact	0,22	medium_impact	-0,89	0,33	0,8	17,11	27,27	N	0,36	N	0,16	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8980	8980	C	A	MI.968	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	454	152	Q	K	Caa/Aaa	-0,8	0,05	0	probably_damaging	0,97	deleterious	0	neutral	4,11	neutral	2,59	neutral	-1,71	neutral_impact	0,6	neutral	0,79	neutral	0,39	deleterious	4,02	23,6	0,41	0,65	neutral	0,37	disease	0,86	disease	0,65	disease	0,8	6	deleterious	1	neutral	0,02	deleterious	2	deleterious	0,75	low_impact	-2,19	low_impact	-1,4	medium_impact	-0,58	0,72	0,9	46,9	8,18	N	0,28	N	0,99	polymorphism	0,51	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15381	15381	C	A	MI.9680	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	635	212	T	N	aCc/aAc	-1,42	0	0	benign	0,18	neutral	0,33	neutral	3,3	neutral	1,26	neutral	2,21	neutral_impact	-2,65	neutral	0,89	neutral	0,91	deleterious	0,87	9,88	0,49	0,55	neutral	0,21	neutral	0,06	neutral	0,14	neutral	0,24	5	neutral	0,61	deleterious	0,58	neutral	-6	neutral	0,1	medium_impact	-0,12	medium_impact	0,06	low_impact	-3,6	0,42	0,8	17,11	27,27	N	0,5	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15381	15381	C	T	MI.9681	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	635	212	T	I	aCc/aTc	-1,42	0	0	benign	0,41	neutral	0,4	neutral	3,13	neutral	-2,8	neutral	-2,27	neutral_impact	0,35	neutral	0,87	neutral	0,84	deleterious	2,76	21,1	0,27	0,45	disease	0,57	neutral	0,32	neutral	0,26	disease	0,59	2	neutral	0,54	deleterious	0,5	neutral	-6	neutral	0,24	medium_impact	-0,58	medium_impact	0,13	medium_impact	-0,88	0,37	0,8	17,11	27,27	N	0,31	N	0,57	polymorphism	1	0,03	rs199721378	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15381	15381	C	G	MI.9682	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	635	212	T	S	aCc/aGc	-1,42	0	0	benign	0,01	neutral	0,42	neutral	3,19	neutral	-1,06	neutral	0,6	neutral_impact	-0,59	neutral	0,96	neutral	0,97	neutral	1,8	14,97	0,57	0,65	neutral	0,2	neutral	0,14	neutral	0,18	neutral	0,3	4	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,09	medium_impact	1,13	medium_impact	0,15	low_impact	-1,73	0,6	0,8	17,11	27,27	N	0,48	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15383	15383	T	A	MI.9683	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	637	213	S	T	Tcc/Acc	-3,71	0	0	probably_damaging	0,99	neutral	0,4	neutral	3,03	deleterious	-3,08	neutral	-2,18	high_impact	3,72	neutral	0,94	neutral	0,43	deleterious	2,24	17,77	0,59	0,65	neutral	0,46	disease	0,62	disease	0,52	neutral	0,44	1	deleterious	0,99	neutral	0,21	deleterious	2	deleterious	0,7	low_impact	-2,59	medium_impact	0,13	high_impact	2,18	0,59	0,8	18,95	18,09	N	0,36	N	0,64	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15383	15383	T	C	MI.9684	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	637	213	S	P	Tcc/Ccc	-3,71	0	0	probably_damaging	1	neutral	0,23	neutral	2,99	neutral	-1,56	deleterious	-3,65	medium_impact	3,14	neutral	0,96	neutral	0,51	deleterious	2,85	21,6	0,1	0,4	disease	0,56	disease	0,64	neutral	0,38	neutral	0,35	3	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,77	low_impact	-3,53	medium_impact	-0,06	medium_impact	1,66	0,15	0,8	18,95	18,09	N	0,41	N	0,4	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15383	15383	T	G	MI.9685	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	637	213	S	A	Tcc/Gcc	-3,71	0	0	probably_damaging	0,99	neutral	0,5	neutral	3,04	neutral	-2,7	neutral	-2,12	high_impact	3,53	neutral	0,97	neutral	0,58	deleterious	3,39	23	0,52	0,6	neutral	0,32	neutral	0,45	disease	0,55	neutral	0,43	1	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,68	low_impact	-2,59	medium_impact	0,22	high_impact	2,01	0,29	0,8	18,95	18,09	N	0,35	N	0,41	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15384	15384	C	G	MI.9686	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	638	213	S	C	tCc/tGc	1,79	0,95	0	probably_damaging	1	neutral	0,18	neutral	2,96	deleterious	-6,18	deleterious	-3,78	high_impact	4,87	neutral	0,95	neutral	0,34	deleterious	3,69	23,3	0,12	0,4	disease	0,85	disease	0,72	disease	0,66	disease	0,69	4	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	-0,14	high_impact	3,23	0,15	0,8	18,95	18,09	P	0,7	P	0,52	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15384	15384	C	A	MI.9687	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	638	213	S	Y	tCc/tAc	1,79	0,95	0	probably_damaging	1	neutral	1	neutral	2,97	deleterious	-4,92	deleterious	-4,59	high_impact	4,62	neutral	0,95	neutral	0,38	deleterious	4,11	23,8	0,1	0,4	disease	0,52	disease	0,8	disease	0,7	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,76	low_impact	-3,53	high_impact	1,85	high_impact	3	0,14	0,8	18,95	18,09	N	0,49	N	0,99	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15384	15384	C	T	MI.9688	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	638	213	S	F	tCc/tTc	1,79	0,95	0	probably_damaging	1	neutral	0,71	neutral	2,97	deleterious	-5,29	deleterious	-4,59	high_impact	4,32	neutral	0,94	neutral	0,45	deleterious	4,32	24	0,12	0,4	disease	0,75	disease	0,8	disease	0,7	disease	0,71	4	deleterious	1	neutral	0,36	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,43	high_impact	2,73	0,06	0,8	18,95	18,09	N	0,45	N	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15386	15386	C	A	MI.9689	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	640	214	H	N	Cat/Aat	-6,93	0	0	benign	0,18	neutral	0,32	neutral	3,42	neutral	4,68	neutral	2,21	neutral_impact	-3,75	neutral	0,93	neutral	0,91	deleterious	0,32	5,88	0,54	0,6	neutral	0,18	neutral	0,1	neutral	0,21	neutral	0,26	5	neutral	0,62	deleterious	0,57	neutral	-6	neutral	0,16	medium_impact	-0,12	medium_impact	0,05	low_impact	-4,6	0,37	0,8	19,21	19,72	N	0,36	N	0,04	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8981	8981	A	G	MI.969	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	455	152	Q	R	cAa/cGa	5,68	1	0	probably_damaging	0,97	neutral	1	neutral	4,5	neutral	4,39	neutral	-0,64	neutral_impact	-2,29	neutral	0,85	neutral	0,67	deleterious	0,8	9,45	0,44	0,65	disease	0,53	neutral	0,22	neutral	0,46	neutral	0,26	5	neutral	0,97	deleterious	0,52	neutral	-2	deleterious	0,69	low_impact	-2,19	high_impact	1,98	low_impact	-3,06	0,69	0,9	46,9	8,18	N	0,44	N	0,91	disease_causing	0,99	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15386	15386	C	T	MI.9690	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	640	214	H	Y	Cat/Tat	-6,93	0	0	benign	0,37	neutral	1	neutral	3,17	neutral	-0,69	neutral	-2,05	neutral_impact	-0,06	neutral	0,94	neutral	0,67	deleterious	2,28	18,06	0,37	0,5	disease	0,57	neutral	0,41	disease	0,53	disease	0,63	3	neutral	0,37	deleterious	0,82	neutral	-6	neutral	0,37	medium_impact	-0,52	high_impact	1,85	low_impact	-1,25	0,38	0,8	19,21	19,72	N	0,23	N	0,61	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15386	15386	C	G	MI.9691	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	640	214	H	D	Cat/Gat	-6,93	0	0	benign	0,18	neutral	0,24	neutral	3,23	neutral	1,06	neutral	2,31	neutral_impact	-2,92	neutral	0,96	neutral	0,95	neutral	0,91	10,14	0,19	0,45	neutral	0,18	neutral	0,1	neutral	0,31	neutral	0,32	4	neutral	0,72	deleterious	0,53	neutral	-6	neutral	0,14	medium_impact	-0,12	medium_impact	-0,05	low_impact	-3,84	0,38	0,8	19,21	19,72	N	0,38	N	0	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15387	15387	A	T	MI.9692	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	641	214	H	L	cAt/cTt	-0,27	0	0	benign	0,18	neutral	0,65	neutral	3,19	neutral	0,53	deleterious	-2,98	low_impact	0,98	neutral	0,95	neutral	0,6	deleterious	3,79	23,4	0,13	0,4	neutral	0,36	neutral	0,49	disease	0,52	disease	0,51	0	neutral	0,23	deleterious	0,74	neutral	-6	neutral	0,26	medium_impact	-0,12	medium_impact	0,37	medium_impact	-0,3	0,16	0,8	19,21	19,72	N	0,25	N	0,75	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15387	15387	A	C	MI.9693	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	641	214	H	P	cAt/cCt	-0,27	0	0	benign	0,37	neutral	0,23	neutral	3,26	neutral	-0,26	neutral	-1,41	neutral_impact	0,08	neutral	0,94	neutral	0,45	deleterious	3,01	22,3	0,08	0,35	neutral	0,48	disease	0,73	disease	0,53	disease	0,6	2	neutral	0,73	neutral	0,43	neutral	-6	deleterious	0,47	medium_impact	-0,52	medium_impact	-0,06	low_impact	-1,12	0,25	0,8	19,21	19,72	N	0,31	N	0,76	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15387	15387	A	G	MI.9694	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	641	214	H	R	cAt/cGt	-0,27	0	0	benign	0,18	neutral	0,34	neutral	3,21	neutral	1,27	neutral	-1,02	neutral_impact	0,12	neutral	0,94	neutral	0,55	deleterious	2,75	21,1	0,29	0,45	neutral	0,28	disease	0,5	neutral	0,5	disease	0,5	0	neutral	0,59	deleterious	0,58	neutral	-6	neutral	0,2	medium_impact	-0,12	medium_impact	0,07	low_impact	-1,08	0,29	0,8	19,21	19,72	N	0,33	N	0,6	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15388	15388	T	A	MI.9695	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	642	214	H	Q	caT/caA	6,61	0,81	0,01	benign	0,01	neutral	0,29	neutral	3,26	neutral	1,29	neutral	-0,15	neutral_impact	0	neutral	0,96	neutral	0,82	deleterious	3,36	22,9	0,41	0,5	neutral	0,21	neutral	0,32	neutral	0,4	neutral	0,43	1	neutral	0,7	deleterious	0,64	neutral	-6	neutral	0,12	medium_impact	1,13	medium_impact	0,01	low_impact	-1,19	0,35	0,8	19,21	19,72	N	0,47	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15388	15388	T	G	MI.9696	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	642	214	H	Q	caT/caG	6,61	0,81	0,01	benign	0,01	neutral	0,29	neutral	3,26	neutral	1,29	neutral	-0,15	neutral_impact	0	neutral	0,96	neutral	0,82	deleterious	3,3	22,9	0,41	0,5	neutral	0,21	neutral	0,32	neutral	0,4	neutral	0,43	1	neutral	0,7	deleterious	0,64	neutral	-6	neutral	0,12	medium_impact	1,13	medium_impact	0,01	low_impact	-1,19	0,35	0,8	19,21	19,72	N	0,46	N	0,41	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15389	15389	T	A	MI.9697	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	643	215	S	T	Tcc/Acc	-1,42	0	0	benign	0,13	neutral	0,4	neutral	3,13	deleterious	-4,06	neutral	-0,38	neutral_impact	0,13	neutral	0,93	neutral	0,86	deleterious	0,72	8,94	0,33	0,5	neutral	0,35	neutral	0,18	neutral	0,21	neutral	0,33	3	neutral	0,53	deleterious	0,64	neutral	-6	neutral	0,11	medium_impact	0,04	medium_impact	0,13	low_impact	-1,08	0,5	0,8	14,21	20,41	N	0,45	N	0,29	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15389	15389	T	C	MI.9698	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	643	215	S	P	Tcc/Ccc	-1,42	0	0	benign	0	neutral	0,23	neutral	3,07	deleterious	-5,88	neutral	-1,32	low_impact	0,82	neutral	0,97	neutral	0,92	deleterious	2,44	19,05	0,13	0,4	disease	0,61	disease	0,58	neutral	0,25	neutral	0,38	2	neutral	0,77	deleterious	0,62	neutral	-6	neutral	0,21	high_impact	2,07	medium_impact	-0,06	medium_impact	-0,45	0,16	0,8	14,21	20,41	N	0,39	N	0,92	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15389	15389	T	G	MI.9699	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	643	215	S	A	Tcc/Gcc	-1,42	0	0	benign	0,08	neutral	0,53	neutral	3,17	deleterious	-3,72	neutral	0,28	neutral_impact	0,31	neutral	0,91	neutral	0,93	neutral	-0,17	1,28	0,33	0,5	neutral	0,29	neutral	0,06	neutral	0,37	neutral	0,24	5	neutral	0,4	deleterious	0,73	neutral	-6	neutral	0,1	medium_impact	0,26	medium_impact	0,25	medium_impact	-0,91	0,2	0,8	14,21	20,41	N	0,41	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8570	8570	T	C	MI.97	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	44	15	L	P	cTa/cCa	-1,49	0	0	probably_damaging	1	deleterious	0,03	neutral	4,38	deleterious	-4,44	deleterious	-5,11	medium_impact	3,48	neutral	0,82	damaging	0,18	deleterious	3,67	23,2	0,2	0,65	disease	0,86	disease	0,88	disease	0,77	disease	0,86	7	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,87	low_impact	-3,6	medium_impact	-0,56	medium_impact	1,89	0,62	0,9	11,5	26,27	N	0,34	N	0,98	disease_causing	0,99	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8981	8981	A	T	MI.970	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	455	152	Q	L	cAa/cTa	5,68	1	0	probably_damaging	0,97	deleterious	0	neutral	3,87	neutral	-1,65	deleterious	-4,7	medium_impact	2,25	neutral	0,79	neutral	0,4	deleterious	3,89	23,5	0,24	0,65	disease	0,76	disease	0,86	disease	0,59	disease	0,78	6	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,85	low_impact	-2,19	low_impact	-1,4	medium_impact	0,83	0,48	0,9	46,9	8,18	N	0,47	N	0,99	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15390	15390	C	A	MI.9700	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	644	215	S	Y	tCc/tAc	-4,86	0	0	probably_damaging	0,93	neutral	1	neutral	3,11	deleterious	-4,72	neutral	-2,3	low_impact	0,84	neutral	0,9	neutral	0,62	deleterious	2,88	21,7	0,13	0,4	neutral	0,3	disease	0,56	neutral	0,26	neutral	0,44	1	neutral	0,93	deleterious	0,54	neutral	-2	deleterious	0,63	low_impact	-1,78	high_impact	1,85	medium_impact	-0,43	0,24	0,8	14,21	20,41	N	0,2	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15390	15390	C	T	MI.9701	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	644	215	S	F	tCc/tTc	-4,86	0	0	probably_damaging	0,99	neutral	0,71	neutral	3,08	neutral	-2	neutral	-2,31	medium_impact	2,19	neutral	0,85	neutral	0,53	deleterious	3,18	22,7	0,12	0,4	neutral	0,49	disease	0,58	neutral	0,3	neutral	0,44	1	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,7	low_impact	-2,59	medium_impact	0,43	medium_impact	0,8	0,1	0,8	14,21	20,41	N	0,19	N	0,91	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15390	15390	C	G	MI.9702	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	644	215	S	C	tCc/tGc	-4,86	0	0	probably_damaging	0,98	neutral	0,18	neutral	3,06	deleterious	-5,76	neutral	-0,57	low_impact	1,81	neutral	0,91	neutral	0,64	deleterious	2,45	19,13	0,15	0,4	disease	0,68	neutral	0,44	neutral	0,27	disease	0,61	2	deleterious	0,99	neutral	0,1	neutral	-2	deleterious	0,68	low_impact	-2,31	medium_impact	-0,14	medium_impact	0,45	0,17	0,8	14,21	20,41	N	0,47	N	0,46	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15392	15392	G	C	MI.9703	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	646	216	D	H	Gat/Cat	-2,8	0	0	probably_damaging	1	neutral	0,54	neutral	2,93	deleterious	-5,86	deleterious	-5,61	high_impact	4,55	neutral	0,91	damaging	0,1	deleterious	3,79	23,4	0,08	0,35	disease	0,7	disease	0,83	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,26	high_impact	2,94	0,31	0,8	58,42	8,61	N	0,38	N	1	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15392	15392	G	A	MI.9704	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	646	216	D	N	Gat/Aat	-2,8	0	0	probably_damaging	1	neutral	0,33	neutral	2,98	deleterious	-4,43	deleterious	-4,01	medium_impact	3,11	neutral	0,87	damaging	0,18	deleterious	4,18	23,8	0,56	0,6	disease	0,54	disease	0,8	disease	0,57	disease	0,64	3	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,81	low_impact	-3,53	medium_impact	0,06	medium_impact	1,63	0,64	0,8	58,42	8,61	N	0,33	N	0,99	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15392	15392	G	T	MI.9705	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	646	216	D	Y	Gat/Tat	-2,8	0	0	probably_damaging	1	neutral	1	neutral	2,94	deleterious	-6,39	deleterious	-7,23	medium_impact	2,73	neutral	0,92	damaging	0,11	deleterious	4,03	23,6	0,03	0,35	disease	0,79	disease	0,92	disease	0,66	disease	0,7	4	deleterious	1	deleterious	0,5	deleterious	1	deleterious	0,88	low_impact	-3,53	high_impact	1,85	medium_impact	1,29	0,06	0,8	58,42	8,61	N	0,22	N	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15393	15393	A	C	MI.9706	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	647	216	D	A	gAt/gCt	9,13	1	0	probably_damaging	1	neutral	0,5	neutral	3	deleterious	-3,21	deleterious	-6,42	high_impact	4,55	neutral	0,93	damaging	0,15	deleterious	3,71	23,3	0,07	0,35	neutral	0,43	disease	0,77	disease	0,67	disease	0,67	3	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,22	high_impact	2,94	0,16	0,8	58,42	8,61	P	0,54	P	0,95	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15393	15393	A	T	MI.9707	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	647	216	D	V	gAt/gTt	9,13	1	0	probably_damaging	1	neutral	0,5	neutral	3,15	neutral	-0,25	deleterious	-7,24	high_impact	4,55	neutral	0,92	damaging	0,12	deleterious	3,94	23,6	0,03	0,35	neutral	0,5	disease	0,9	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,22	high_impact	2,94	0,02	0,8	58,42	8,61	P	0,55	P	1	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15393	15393	A	G	MI.9708	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	647	216	D	G	gAt/gGt	9,13	1	0	probably_damaging	1	neutral	0,33	neutral	2,94	neutral	-1,98	deleterious	-5,63	high_impact	3,98	neutral	0,93	damaging	0,17	deleterious	4,1	23,7	0,07	0,35	disease	0,65	disease	0,84	disease	0,67	disease	0,71	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,06	high_impact	2,42	0,11	0,8	58,42	8,61	P	0,57	P	1	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15394	15394	T	G	MI.9709	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	648	216	D	E	gaT/gaG	6,84	1	0	probably_damaging	0,99	neutral	0,28	neutral	3,03	deleterious	-3,73	deleterious	-3,17	medium_impact	2,67	neutral	0,91	damaging	0,12	deleterious	3,61	23,2	0,3	0,45	neutral	0,4	disease	0,74	disease	0,53	neutral	0,39	2	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,78	low_impact	-2,59	medium_impact	0	medium_impact	1,23	0,53	0,8	58,42	8,61	N	0,53	P	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8981	8981	A	C	MI.971	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	455	152	Q	P	cAa/cCa	5,68	1	0	probably_damaging	0,98	deleterious	0	neutral	3,89	neutral	-2,53	deleterious	-4,25	low_impact	1,9	neutral	0,67	neutral	0,41	deleterious	3,43	23	0,16	0,65	disease	0,83	disease	0,94	disease	0,61	disease	0,83	7	deleterious	1	neutral	0,01	deleterious	2	deleterious	0,91	low_impact	-2,36	low_impact	-1,4	medium_impact	0,53	0,56	0,9	46,9	8,18	N	0,4	N	0,98	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15394	15394	T	A	MI.9710	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	648	216	D	E	gaT/gaA	6,84	1	0	probably_damaging	0,99	neutral	0,28	neutral	3,03	deleterious	-3,73	deleterious	-3,17	medium_impact	2,67	neutral	0,91	damaging	0,12	deleterious	3,72	23,3	0,3	0,45	neutral	0,4	disease	0,74	disease	0,53	neutral	0,39	2	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,78	low_impact	-2,59	medium_impact	0	medium_impact	1,23	0,53	0,8	58,42	8,61	N	0,54	P	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15395	15395	A	G	MI.9711	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	649	217	K	E	Aaa/Gaa	-0,73	0,16	0	probably_damaging	1	neutral	0,37	neutral	3,04	deleterious	-3,26	deleterious	-3,22	high_impact	5,15	neutral	0,92	damaging	0,17	deleterious	3,58	23,2	0,14	0,4	disease	0,69	disease	0,86	disease	0,74	disease	0,71	4	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,1	high_impact	3,48	0,35	0,8	28,42	14,16	P	0,69	P	0,95	polymorphism	1	0,27	.	.	.	.	.	.	COSM3307732	.	.	A15395G	Possible LHON factor	+	-	Reported	1
chrM	15395	15395	A	C	MI.9712	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	649	217	K	Q	Aaa/Caa	-0,73	0,16	0	probably_damaging	1	neutral	0,34	neutral	3	deleterious	-3,73	deleterious	-3,2	high_impact	4,69	neutral	0,91	damaging	0,18	deleterious	2,92	21,9	0,23	0,45	disease	0,53	disease	0,8	disease	0,62	disease	0,66	3	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,07	high_impact	3,07	0,24	0,8	28,42	14,16	N	0,58	P	0,93	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15396	15396	A	C	MI.9713	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	650	217	K	T	aAa/aCa	6,84	1	0	probably_damaging	1	neutral	0,48	neutral	3	neutral	-1,1	deleterious	-4,82	high_impact	4,11	neutral	0,95	damaging	0,27	deleterious	3,65	23,2	0,07	0,35	disease	0,77	disease	0,84	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,24	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,2	high_impact	2,54	0,09	0,8	28,42	14,16	P	0,61	P	0,88	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15396	15396	A	T	MI.9714	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	650	217	K	M	aAa/aTa	6,84	1	0	probably_damaging	1	neutral	0,23	neutral	2,96	neutral	-2,86	deleterious	-4,76	medium_impact	3,24	neutral	0,96	neutral	0,78	deleterious	2,85	21,6	0,07	0,35	disease	0,9	disease	0,76	neutral	0,44	disease	0,54	1	deleterious	1	neutral	0,12	deleterious	1	deleterious	0,79	low_impact	-3,53	medium_impact	-0,06	medium_impact	1,75	0,17	0,8	28,42	14,16	P	0,59	P	0,67	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15397	15397	A	C	MI.9715	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	651	217	K	N	aaA/aaC	3,85	1	0	probably_damaging	1	neutral	0,41	neutral	2,99	deleterious	-4,02	deleterious	-4,03	high_impact	4,17	neutral	0,91	damaging	0,2	deleterious	3,83	23,4	0,3	0,45	disease	0,76	disease	0,81	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,14	high_impact	2,59	0,23	0,8	28,42	14,16	N	0,56	P	0,84	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15397	15397	A	T	MI.9716	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	651	217	K	N	aaA/aaT	3,85	1	0	probably_damaging	1	neutral	0,41	neutral	2,99	deleterious	-4,02	deleterious	-4,03	high_impact	4,17	neutral	0,91	damaging	0,2	deleterious	3,9	23,5	0,3	0,45	disease	0,76	disease	0,81	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,14	high_impact	2,59	0,23	0,8	28,42	14,16	P	0,59	P	0,84	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15398	15398	A	C	MI.9717	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	652	218	I	L	Atc/Ctc	4,77	1	0	benign	0,26	neutral	0,64	neutral	3,06	deleterious	-3,65	neutral	-1,6	high_impact	3,62	neutral	0,94	neutral	0,35	deleterious	1,98	16,11	0,24	0,45	neutral	0,44	disease	0,76	disease	0,51	disease	0,55	1	neutral	0,25	deleterious	0,69	neutral	-2	neutral	0,29	medium_impact	-0,31	medium_impact	0,36	high_impact	2,09	0,63	0,8	56,58	8,01	N	0,47	N	0,87	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15398	15398	A	T	MI.9718	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	652	218	I	F	Atc/Ttc	4,77	1	0	possibly_damaging	0,88	neutral	0,7	neutral	3,03	deleterious	-5,44	deleterious	-3,22	high_impact	4,5	neutral	0,95	neutral	0,37	deleterious	3,48	23,1	0,08	0,35	disease	0,78	disease	0,86	disease	0,69	disease	0,69	4	neutral	0,86	neutral	0,41	deleterious	1	deleterious	0,81	low_impact	-1,54	medium_impact	0,42	high_impact	2,89	0,58	0,8	56,58	8,01	P	0,58	P	0,97	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15398	15398	A	G	MI.9719	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	652	218	I	V	Atc/Gtc	4,77	1	0	benign	0,01	neutral	0,51	neutral	3,17	neutral	-1,73	neutral	-0,63	low_impact	1,18	neutral	0,98	neutral	0,82	deleterious	0,04	2,96	0,3	0,45	neutral	0,28	neutral	0,35	neutral	0,29	neutral	0,4	2	neutral	0,47	deleterious	0,75	neutral	-6	neutral	0,16	medium_impact	1,13	medium_impact	0,23	medium_impact	-0,12	0,4	0,8	56,58	8,01	P	0,57	P	0,84	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8982	8982	A	C	MI.972	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	456	152	Q	H	caA/caC	4,99	1	0	probably_damaging	1	deleterious	0	neutral	3,86	neutral	-1,81	deleterious	-2,95	low_impact	1,9	neutral	0,79	neutral	0,36	deleterious	3,97	23,6	0,45	0,65	disease	0,76	disease	0,72	disease	0,59	disease	0,71	4	deleterious	1	neutral	0	deleterious	2	deleterious	0,84	low_impact	-3,6	low_impact	-1,4	medium_impact	0,53	0,73	0,9	46,9	8,18	N	0,42	N	0,97	disease_causing	0,97	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15399	15399	T	G	MI.9720	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	653	218	I	S	aTc/aGc	4,54	1	0	probably_damaging	0,99	neutral	0,42	neutral	3,08	deleterious	-5,72	deleterious	-4,75	high_impact	3,81	neutral	0,94	neutral	0,37	deleterious	4,39	24,1	0,02	0,35	disease	0,81	disease	0,89	disease	0,71	disease	0,71	4	deleterious	0,99	neutral	0,22	deleterious	2	deleterious	0,88	low_impact	-2,59	medium_impact	0,15	high_impact	2,27	0,22	0,8	56,58	8,01	N	0,51	P	0,98	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15399	15399	T	C	MI.9721	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	653	218	I	T	aTc/aCc	4,54	1	0	probably_damaging	0,98	neutral	0,39	neutral	3,08	deleterious	-5,05	deleterious	-3,86	high_impact	3,61	neutral	0,94	neutral	0,38	deleterious	3,54	23,1	0,03	0,35	disease	0,73	disease	0,81	disease	0,59	disease	0,58	2	neutral	0,98	neutral	0,21	deleterious	2	deleterious	0,83	low_impact	-2,31	medium_impact	0,12	high_impact	2,08	0,18	0,8	56,58	8,01	N	0,47	N	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15399	15399	T	A	MI.9722	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	653	218	I	N	aTc/aAc	4,54	1	0	probably_damaging	1	neutral	0,32	neutral	3,16	deleterious	-6,9	deleterious	-5,56	high_impact	4,76	neutral	0,91	neutral	0,38	deleterious	4,63	24,5	0,04	0,35	disease	0,9	disease	0,88	disease	0,6	disease	0,66	3	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,05	high_impact	3,13	0,27	0,8	56,58	8,01	P	0,71	P	0,99	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15400	15400	C	G	MI.9723	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	654	218	I	M	atC/atG	3,63	1	0	probably_damaging	0,94	neutral	0,22	neutral	3,04	deleterious	-5,32	neutral	-2,29	high_impact	3,96	neutral	0,94	neutral	0,36	deleterious	3,29	22,8	0,13	0,4	disease	0,76	disease	0,73	disease	0,51	neutral	0,5	0	neutral	0,96	neutral	0,14	deleterious	2	deleterious	0,69	low_impact	-1,85	medium_impact	-0,08	high_impact	2,4	0,56	0,8	56,58	8,01	N	0,49	N	0,82	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15400	15400	C	A	MI.9724	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	654	218	I	M	atC/atA	3,63	1	0	probably_damaging	0,94	neutral	0,22	neutral	3,04	deleterious	-5,32	neutral	-2,29	high_impact	3,96	neutral	0,94	neutral	0,36	deleterious	3,72	23,3	0,13	0,4	disease	0,76	disease	0,73	disease	0,51	neutral	0,5	0	neutral	0,96	neutral	0,14	deleterious	2	deleterious	0,69	low_impact	-1,85	medium_impact	-0,08	high_impact	2,4	0,56	0,8	56,58	8,01	N	0,5	N	0,82	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15401	15401	A	C	MI.9725	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	655	219	T	P	Acc/Ccc	-2,8	0	0	possibly_damaging	0,79	neutral	0,24	neutral	3,51	neutral	2,76	neutral	2,82	neutral_impact	-2,52	neutral	0,92	neutral	0,94	deleterious	0,68	8,72	0,05	0,35	neutral	0,22	neutral	0,05	neutral	0,14	neutral	0,23	5	neutral	0,86	neutral	0,23	neutral	-3	deleterious	0,59	low_impact	-1,27	medium_impact	-0,05	low_impact	-3,48	0,25	0,8	25,53	30,43	N	0,49	N	0,01	polymorphism	1	0,01	rs200521299	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15401	15401	A	G	MI.9726	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	655	219	T	A	Acc/Gcc	-2,8	0	0	benign	0,03	neutral	0,5	neutral	3,19	neutral	0,44	neutral	-0,24	low_impact	1,51	neutral	0,81	neutral	0,8	deleterious	3,19	22,7	0,28	0,45	neutral	0,21	neutral	0,25	disease	0,54	neutral	0,42	2	neutral	0,47	deleterious	0,74	neutral	-6	neutral	0,15	medium_impact	0,68	medium_impact	0,22	medium_impact	0,18	0,29	0,8	25,53	30,43	N	0,32	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15401	15401	A	T	MI.9727	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	655	219	T	S	Acc/Tcc	-2,8	0	0	benign	0,4	neutral	0,41	neutral	3,21	neutral	0,75	neutral	0,46	neutral_impact	-1,19	neutral	0,81	neutral	0,79	deleterious	1,87	15,42	0,39	0,5	neutral	0,26	neutral	0,14	neutral	0,23	neutral	0,29	4	neutral	0,53	deleterious	0,51	neutral	-6	neutral	0,34	medium_impact	-0,57	medium_impact	0,14	low_impact	-2,27	0,32	0,8	25,53	30,43	N	0,35	N	0,34	polymorphism	1	0,01	rs200521299	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15402	15402	C	T	MI.9728	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	656	219	T	I	aCc/aTc	0,18	0	0	possibly_damaging	0,66	neutral	0,43	neutral	3,14	neutral	-1,2	neutral	-2,04	low_impact	1,61	neutral	0,76	neutral	0,6	deleterious	3,96	23,6	0,2	0,45	neutral	0,24	neutral	0,49	disease	0,53	disease	0,54	1	neutral	0,66	neutral	0,39	neutral	-3	deleterious	0,51	medium_impact	-1	medium_impact	0,16	medium_impact	0,27	0,39	0,8	25,53	30,43	N	0,25	N	0,56	polymorphism	1	0,04	rs879163418	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15402	15402	C	G	MI.9729	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	656	219	T	S	aCc/aGc	0,18	0	0	benign	0,4	neutral	0,41	neutral	3,21	neutral	0,75	neutral	0,46	neutral_impact	-1,19	neutral	0,81	neutral	0,79	deleterious	2,1	16,84	0,39	0,5	neutral	0,26	neutral	0,14	neutral	0,23	neutral	0,29	4	neutral	0,53	deleterious	0,51	neutral	-6	neutral	0,34	medium_impact	-0,57	medium_impact	0,14	low_impact	-2,27	0,32	0,8	25,53	30,43	N	0,38	N	0,34	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8982	8982	A	T	MI.973	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	456	152	Q	H	caA/caT	4,99	1	0	probably_damaging	1	deleterious	0	neutral	3,86	neutral	-1,81	deleterious	-2,95	low_impact	1,9	neutral	0,79	neutral	0,36	deleterious	4,13	23,8	0,45	0,65	disease	0,76	disease	0,72	disease	0,59	disease	0,71	4	deleterious	1	neutral	0	deleterious	2	deleterious	0,84	low_impact	-3,6	low_impact	-1,4	medium_impact	0,53	0,73	0,9	46,9	8,18	N	0,43	N	0,97	disease_causing	0,97	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15402	15402	C	A	MI.9730	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	656	219	T	N	aCc/aAc	0,18	0	0	possibly_damaging	0,79	neutral	0,31	neutral	3,17	neutral	-0,02	neutral	-0,77	low_impact	1,26	neutral	0,83	neutral	0,63	deleterious	3,6	23,2	0,36	0,5	neutral	0,49	disease	0,64	disease	0,56	disease	0,68	4	neutral	0,82	neutral	0,26	neutral	-3	deleterious	0,64	low_impact	-1,27	medium_impact	0,03	medium_impact	-0,05	0,41	0,8	25,53	30,43	N	0,3	N	0,58	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15404	15404	T	A	MI.9731	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	658	220	F	I	Ttc/Atc	-1,88	0	0	probably_damaging	1	neutral	0,4	neutral	2,99	neutral	-1,05	deleterious	-4,88	high_impact	5,27	neutral	0,94	neutral	0,49	deleterious	4,27	23,9	0,06	0,35	disease	0,63	disease	0,74	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,13	high_impact	3,59	0,46	0,8	58,16	8,58	P	0,7	P	0,98	polymorphism	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15404	15404	T	G	MI.9732	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	658	220	F	V	Ttc/Gtc	-1,88	0	0	probably_damaging	1	neutral	0,5	neutral	2,93	neutral	-1,65	deleterious	-5,69	high_impact	4,72	neutral	0,95	neutral	0,5	deleterious	4,1	23,7	0,04	0,35	disease	0,59	disease	0,82	disease	0,81	disease	0,74	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,22	high_impact	3,09	0,27	0,8	58,16	8,58	P	0,7	P	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15404	15404	T	C	MI.9733	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	658	220	F	L	Ttc/Ctc	-1,88	0	0	probably_damaging	0,99	neutral	0,65	neutral	2,99	neutral	-1,07	deleterious	-4,88	high_impact	4,58	neutral	0,95	neutral	0,45	deleterious	3,75	23,3	0,09	0,35	disease	0,56	disease	0,74	disease	0,72	disease	0,69	4	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,81	low_impact	-2,59	medium_impact	0,37	high_impact	2,97	0,65	0,8	58,16	8,58	N	0,44	N	0,91	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15405	15405	T	G	MI.9734	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	659	220	F	C	tTc/tGc	3,63	1	0	probably_damaging	1	neutral	0,18	neutral	2,83	deleterious	-4,52	deleterious	-6,5	high_impact	5,27	neutral	0,94	neutral	0,41	deleterious	4,17	23,8	0,02	0,35	disease	0,86	disease	0,78	disease	0,82	disease	0,73	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,14	high_impact	3,59	0,16	0,8	58,16	8,58	P	0,65	P	0,99	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15405	15405	T	C	MI.9735	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	659	220	F	S	tTc/tCc	3,63	1	0	probably_damaging	1	neutral	0,4	neutral	2,86	deleterious	-3,19	deleterious	-6,5	high_impact	4,64	neutral	0,96	neutral	0,47	deleterious	4,24	23,9	0,02	0,35	disease	0,57	disease	0,81	disease	0,81	disease	0,72	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	0,13	high_impact	3,02	0,24	0,8	58,16	8,58	P	0,63	P	0,99	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15405	15405	T	A	MI.9736	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	659	220	F	Y	tTc/tAc	3,63	1	0	probably_damaging	0,99	neutral	1	neutral	2,84	deleterious	-3,65	neutral	-2,44	high_impact	5,27	neutral	0,94	neutral	0,45	deleterious	3,92	23,5	0,1	0,4	disease	0,71	disease	0,72	disease	0,75	disease	0,71	4	deleterious	0,99	deleterious	0,51	deleterious	2	deleterious	0,84	low_impact	-2,59	high_impact	1,85	high_impact	3,59	0,52	0,8	58,16	8,58	P	0,72	P	0,88	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15406	15406	C	A	MI.9737	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	660	220	F	L	ttC/ttA	5,69	1	0	probably_damaging	0,99	neutral	0,65	neutral	2,99	neutral	-1,07	deleterious	-4,88	high_impact	4,58	neutral	0,95	neutral	0,45	deleterious	4,34	24	0,09	0,35	disease	0,56	disease	0,74	disease	0,72	disease	0,69	4	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,81	low_impact	-2,59	medium_impact	0,37	high_impact	2,97	0,65	0,8	58,16	8,58	P	0,62	P	0,91	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15406	15406	C	G	MI.9738	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	660	220	F	L	ttC/ttG	5,69	1	0	probably_damaging	0,99	neutral	0,65	neutral	2,99	neutral	-1,07	deleterious	-4,88	high_impact	4,58	neutral	0,95	neutral	0,45	deleterious	4,05	23,7	0,09	0,35	disease	0,56	disease	0,74	disease	0,72	disease	0,69	4	deleterious	0,99	neutral	0,33	deleterious	2	deleterious	0,81	low_impact	-2,59	medium_impact	0,37	high_impact	2,97	0,65	0,8	58,16	8,58	P	0,61	P	0,91	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15407	15407	C	G	MI.9739	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	661	221	H	D	Cac/Gac	-1,65	0	0	probably_damaging	1	neutral	0,27	neutral	3,06	deleterious	-5,37	deleterious	-7,27	high_impact	4,76	neutral	0,92	neutral	0,32	deleterious	3,63	23,2	0,04	0,35	neutral	0,46	disease	0,85	disease	0,85	disease	0,76	5	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	-0,01	high_impact	3,13	0,24	0,8	57,63	8,82	P	0,63	P	0,98	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8983	8983	C	T	MI.974	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	457	153	P	S	Cca/Tca	-0,1	0,65	0	probably_damaging	1	deleterious	0	neutral	3,92	deleterious	-3,28	deleterious	-7,03	medium_impact	3,34	neutral	0,6	damaging	0,05	deleterious	3,93	23,5	0,44	0,65	disease	0,73	disease	0,84	disease	0,73	disease	0,74	5	deleterious	1	neutral	0	deleterious	5	deleterious	0,84	low_impact	-3,6	low_impact	-1,4	medium_impact	1,77	0,29	0,9	49,56	8,78	N	0,27	N	0,82	disease_causing	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15407	15407	C	T	MI.9740	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	661	221	H	Y	Cac/Tac	-1,65	0	0	probably_damaging	0,99	neutral	1	neutral	3,2	deleterious	-6,95	deleterious	-4,85	medium_impact	3,06	neutral	0,97	neutral	0,39	deleterious	2,14	17,13	0,11	0,4	neutral	0,39	disease	0,84	disease	0,77	disease	0,59	2	deleterious	0,99	deleterious	0,51	deleterious	1	deleterious	0,8	low_impact	-2,59	high_impact	1,85	medium_impact	1,59	0,19	0,8	57,63	8,82	N	0,33	N	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15407	15407	C	A	MI.9741	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	661	221	H	N	Cac/Aac	-1,65	0	0	probably_damaging	0,99	neutral	0,3	neutral	3,07	deleterious	-5,86	deleterious	-5,64	medium_impact	3,5	neutral	0,93	neutral	0,41	deleterious	2,31	18,26	0,21	0,45	neutral	0,42	disease	0,85	disease	0,79	disease	0,72	4	deleterious	0,99	neutral	0,16	deleterious	1	deleterious	0,78	low_impact	-2,59	medium_impact	0,02	medium_impact	1,98	0,18	0,8	57,63	8,82	N	0,47	N	0,97	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15408	15408	A	T	MI.9742	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	662	221	H	L	cAc/cTc	5,46	1	0	probably_damaging	0,99	neutral	0,67	neutral	3,2	deleterious	-6,65	deleterious	-8,89	high_impact	3,94	neutral	0,95	neutral	0,36	deleterious	2,8	21,3	0,03	0,35	disease	0,51	disease	0,9	disease	0,83	disease	0,77	5	deleterious	0,99	neutral	0,34	deleterious	2	deleterious	0,82	low_impact	-2,59	medium_impact	0,39	high_impact	2,38	0,12	0,8	57,63	8,82	P	0,56	P	0,92	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15408	15408	A	C	MI.9743	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	662	221	H	P	cAc/cCc	5,46	1	0	probably_damaging	1	neutral	0,24	neutral	3,09	deleterious	-6,73	deleterious	-8,08	high_impact	4,76	neutral	0,94	damaging	0,25	deleterious	3,46	23	0,03	0,35	disease	0,65	disease	0,86	disease	0,79	disease	0,72	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,05	high_impact	3,13	0,1	0,8	57,63	8,82	P	0,68	P	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15408	15408	A	G	MI.9744	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	662	221	H	R	cAc/cGc	5,46	1	0	probably_damaging	0,99	neutral	0,34	neutral	3,09	deleterious	-6,07	deleterious	-6,46	high_impact	4,91	neutral	0,94	neutral	0,31	deleterious	1,93	15,75	0,07	0,35	neutral	0,45	disease	0,86	disease	0,82	disease	0,73	5	deleterious	0,99	neutral	0,18	deleterious	2	deleterious	0,81	low_impact	-2,59	medium_impact	0,07	high_impact	3,26	0,23	0,8	57,63	8,82	P	0,68	P	0,98	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15409	15409	C	A	MI.9745	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	663	221	H	Q	caC/caA	8,44	1	0	probably_damaging	1	neutral	0,28	neutral	3,07	deleterious	-6,2	deleterious	-6,46	high_impact	4,76	neutral	0,96	neutral	0,37	deleterious	2,35	18,46	0,11	0,4	neutral	0,31	disease	0,82	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0	high_impact	3,13	0,26	0,8	57,63	8,82	P	0,65	P	0,94	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15409	15409	C	G	MI.9746	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	663	221	H	Q	caC/caG	8,44	1	0	probably_damaging	1	neutral	0,28	neutral	3,07	deleterious	-6,2	deleterious	-6,46	high_impact	4,76	neutral	0,96	neutral	0,37	deleterious	2,07	16,64	0,11	0,4	neutral	0,31	disease	0,82	disease	0,79	disease	0,71	4	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0	high_impact	3,13	0,26	0,8	57,63	8,82	P	0,65	P	0,94	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15410	15410	C	T	MI.9747	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	664	222	P	S	Cct/Tct	0,18	0,98	0	probably_damaging	1	neutral	0,4	neutral	2,49	deleterious	-4,72	deleterious	-6,4	medium_impact	3,11	neutral	0,75	neutral	0,47	deleterious	3,86	23,5	0,07	0,35	neutral	0,43	disease	0,82	neutral	0,39	neutral	0,49	0	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,82	low_impact	-3,53	medium_impact	0,13	medium_impact	1,63	0,17	0,8	57,37	8,69	N	0,43	N	0,85	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15410	15410	C	A	MI.9748	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	664	222	P	T	Cct/Act	0,18	0,98	0	probably_damaging	1	neutral	0,38	neutral	2,49	deleterious	-5,15	deleterious	-6,39	medium_impact	2,86	neutral	0,81	neutral	0,45	deleterious	3,87	23,5	0,06	0,35	disease	0,66	disease	0,82	disease	0,56	disease	0,52	0	deleterious	1	neutral	0,19	deleterious	1	deleterious	0,83	low_impact	-3,53	medium_impact	0,11	medium_impact	1,4	0,46	0,8	57,37	8,69	N	0,34	N	0,96	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15410	15410	C	G	MI.9749	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	664	222	P	A	Cct/Gct	0,18	0,98	0	probably_damaging	1	neutral	0,5	neutral	2,49	deleterious	-4,41	deleterious	-6,4	high_impact	4,29	neutral	0,83	neutral	0,51	deleterious	2,97	22,1	0,08	0,35	disease	0,59	disease	0,63	disease	0,73	disease	0,62	2	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,22	high_impact	2,7	0,56	0,8	57,37	8,69	N	0,47	N	0,82	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8983	8983	C	A	MI.975	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	457	153	P	T	Cca/Aca	-0,1	0,65	0	probably_damaging	1	deleterious	0	neutral	4	neutral	-2,07	deleterious	-7,03	high_impact	3,59	neutral	0,61	damaging	0,04	deleterious	3,9	23,5	0,32	0,65	disease	0,54	disease	0,79	disease	0,72	disease	0,72	4	deleterious	1	neutral	0	deleterious	6	deleterious	0,8	low_impact	-3,6	low_impact	-1,4	medium_impact	1,98	0,77	0,9	49,56	8,78	N	0,28	N	0,93	disease_causing	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15411	15411	C	T	MI.9750	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	665	222	P	L	cCt/cTt	7,07	1	0	probably_damaging	1	neutral	0,65	neutral	2,47	deleterious	-5,62	deleterious	-8,03	high_impact	4,36	neutral	0,83	neutral	0,38	deleterious	4,38	24,1	0,04	0,35	disease	0,76	disease	0,88	disease	0,71	disease	0,71	4	deleterious	1	neutral	0,33	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,37	high_impact	2,77	0,72	0,85	57,37	8,69	P	0,57	P	1	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15411	15411	C	G	MI.9751	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	665	222	P	R	cCt/cGt	7,07	1	0	probably_damaging	1	neutral	0,34	neutral	2,47	deleterious	-4,95	deleterious	-7,23	high_impact	5,11	neutral	0,83	neutral	0,37	deleterious	3,71	23,3	0,03	0,35	disease	0,67	disease	0,89	disease	0,82	disease	0,76	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,07	high_impact	3,45	0,48	0,8	57,37	8,69	P	0,71	P	0,81	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15411	15411	C	A	MI.9752	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	665	222	P	H	cCt/cAt	7,07	1	0	probably_damaging	1	neutral	0,56	neutral	2,44	deleterious	-6,23	deleterious	-7,23	high_impact	4,55	neutral	0,78	neutral	0,33	deleterious	4,07	23,7	0,04	0,35	disease	0,8	disease	0,85	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,28	high_impact	2,94	0,31	0,8	57,37	8,69	N	0,52	P	0,71	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15413	15413	T	A	MI.9753	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	667	223	Y	N	Tac/Aac	-20	0	0	probably_damaging	1	neutral	0,3	neutral	3,12	deleterious	-5,22	deleterious	-7,23	high_impact	4,19	neutral	0,92	damaging	0,13	deleterious	4,07	23,7	0,05	0,35	neutral	0,49	disease	0,89	disease	0,83	disease	0,77	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,02	high_impact	2,61	0,07	0,8	58,95	8,71	N	0,45	N	0,99	polymorphism	1	0,25	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15413	15413	T	G	MI.9754	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	667	223	Y	D	Tac/Gac	-20	0	0	probably_damaging	1	neutral	0,21	neutral	3,13	deleterious	-5,99	deleterious	-8,02	high_impact	4,96	neutral	0,9	damaging	0,1	deleterious	4,04	23,7	0,02	0,35	disease	0,61	disease	0,9	disease	0,86	disease	0,78	6	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,09	high_impact	3,31	0,11	0,8	58,95	8,71	P	0,62	P	1	disease_causing	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15413	15413	T	C	MI.9755	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	667	223	Y	H	Tac/Cac	-20	0	0	probably_damaging	1	neutral	0,53	neutral	3,1	deleterious	-4,85	deleterious	-4,02	high_impact	3,86	neutral	0,92	damaging	0,09	deleterious	3,57	23,1	0,1	0,4	disease	0,73	disease	0,82	disease	0,86	disease	0,76	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,87	low_impact	-3,53	medium_impact	0,25	high_impact	2,31	0,17	0,8	58,95	8,71	N	0,29	N	0,98	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15414	15414	A	G	MI.9756	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	668	223	Y	C	tAc/tGc	5,69	1	0	probably_damaging	1	neutral	0,17	neutral	3,09	deleterious	-4,47	deleterious	-7,21	high_impact	5,16	neutral	0,94	damaging	0,07	deleterious	3,61	23,2	0,04	0,35	disease	0,84	disease	0,87	disease	0,83	disease	0,74	5	deleterious	1	neutral	0,09	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,15	high_impact	3,49	0,1	0,8	58,95	8,71	P	0,73	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15414	15414	A	T	MI.9757	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	668	223	Y	F	tAc/tTc	5,69	1	0	probably_damaging	1	neutral	0,69	neutral	3,06	neutral	0,1	deleterious	-3,1	medium_impact	2,75	neutral	0,95	damaging	0,11	deleterious	1,94	15,8	0,18	0,45	disease	0,7	disease	0,8	disease	0,56	neutral	0,47	1	deleterious	1	neutral	0,35	deleterious	1	deleterious	0,84	low_impact	-3,53	medium_impact	0,41	medium_impact	1,3	0,37	0,8	58,95	8,71	N	0,43	N	0,83	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15414	15414	A	C	MI.9758	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	668	223	Y	S	tAc/tCc	5,69	1	0	probably_damaging	1	neutral	0,38	neutral	3,12	deleterious	-4,38	deleterious	-7,21	high_impact	4,61	neutral	0,92	damaging	0,11	deleterious	3,7	23,3	0,04	0,35	disease	0,53	disease	0,87	disease	0,8	disease	0,74	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,11	high_impact	2,99	0,13	0,8	58,95	8,71	P	0,64	P	1	polymorphism	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15416	15416	T	A	MI.9759	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	670	224	Y	N	Tac/Aac	-0,5	0,15	0	probably_damaging	0,96	neutral	0,21	neutral	3,31	neutral	-2,98	deleterious	-5,79	high_impact	4,51	neutral	0,92	neutral	0,47	deleterious	4,23	23,9	0,03	0,35	disease	0,88	disease	0,89	disease	0,72	disease	0,79	6	neutral	0,97	neutral	0,13	deleterious	2	deleterious	0,88	low_impact	-2,02	medium_impact	-0,09	high_impact	2,9	0,27	0,8	45,53	8,25	N	0,55	P	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8983	8983	C	G	MI.976	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	457	153	P	A	Cca/Gca	-0,1	0,65	0	probably_damaging	1	neutral	0,08	neutral	4,03	neutral	-1,79	deleterious	-7,03	medium_impact	2,26	damaging	0,59	damaging	0,07	deleterious	3,14	22,6	0,27	0,65	neutral	0,32	disease	0,64	disease	0,73	disease	0,6	2	deleterious	1	neutral	0,04	deleterious	1	deleterious	0,73	low_impact	-3,6	medium_impact	-0,31	medium_impact	0,84	0,72	0,9	49,56	8,78	N	0,26	N	0,79	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15416	15416	T	G	MI.9760	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	670	224	Y	D	Tac/Gac	-0,5	0,15	0	probably_damaging	0,98	neutral	0,19	neutral	3,12	deleterious	-3,29	deleterious	-6,1	high_impact	4,51	neutral	0,9	neutral	0,37	deleterious	3,98	23,6	0,02	0,35	disease	0,93	disease	0,91	disease	0,82	disease	0,84	7	deleterious	0,98	neutral	0,11	deleterious	2	deleterious	0,9	low_impact	-2,31	medium_impact	-0,12	high_impact	2,9	0,2	0,8	45,53	8,25	P	0,62	P	1	disease_causing	1	0,39	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15416	15416	T	C	MI.9761	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	670	224	Y	H	Tac/Cac	-0,5	0,15	0	probably_damaging	0,98	neutral	0,36	neutral	3,12	neutral	-2,57	deleterious	-3,54	medium_impact	2,99	neutral	0,94	neutral	0,6	deleterious	2,55	19,78	0,08	0,35	disease	0,81	disease	0,77	disease	0,64	disease	0,7	4	deleterious	0,98	neutral	0,19	deleterious	1	deleterious	0,87	low_impact	-2,31	medium_impact	0,09	medium_impact	1,52	0,34	0,8	45,53	8,25	N	0,37	N	0,98	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15417	15417	A	C	MI.9762	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	671	224	Y	S	tAc/tCc	3,63	0,97	0	possibly_damaging	0,83	neutral	0,34	neutral	3,15	neutral	-2,22	deleterious	-5,29	high_impact	3,62	neutral	0,93	neutral	0,5	deleterious	3,7	23,3	0,03	0,35	disease	0,84	disease	0,84	disease	0,72	disease	0,77	5	neutral	0,85	neutral	0,26	deleterious	1	deleterious	0,84	low_impact	-1,37	medium_impact	0,07	high_impact	2,09	0,36	0,8	45,53	8,25	N	0,54	P	1	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15417	15417	A	G	MI.9763	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	671	224	Y	C	tAc/tGc	3,63	0,97	0	benign	0,1	neutral	0,11	neutral	3,09	deleterious	-3,87	deleterious	-5,29	high_impact	4,51	neutral	0,92	neutral	0,45	deleterious	3,61	23,2	0,02	0,35	disease	0,92	disease	0,89	disease	0,76	disease	0,83	7	neutral	0,88	deleterious	0,51	neutral	-2	neutral	0,38	medium_impact	0,16	medium_impact	-0,27	high_impact	2,9	0,17	0,8	45,53	8,25	P	0,54	P	1	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15417	15417	A	T	MI.9764	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	671	224	Y	F	tAc/tTc	3,63	0,97	0	possibly_damaging	0,72	neutral	0,81	neutral	3,28	neutral	0,71	neutral	0,26	neutral_impact	-0,68	neutral	0,96	neutral	0,68	neutral	1,39	12,73	0,19	0,45	neutral	0,24	neutral	0,14	neutral	0,25	neutral	0,25	5	neutral	0,67	deleterious	0,55	neutral	-3	deleterious	0,59	low_impact	-1,11	medium_impact	0,56	low_impact	-1,81	0,58	0,8	45,53	8,25	N	0,43	N	0,83	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15419	15419	A	C	MI.9765	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	673	225	T	P	Aca/Cca	-3,26	0	0	probably_damaging	1	neutral	0,22	neutral	3,04	deleterious	-3,13	neutral	-2,38	high_impact	3,87	neutral	0,98	neutral	0,32	deleterious	3,44	23	0,03	0,35	disease	0,69	disease	0,91	neutral	0,46	disease	0,71	4	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,86	low_impact	-3,53	medium_impact	-0,08	high_impact	2,32	0,43	0,8	57,11	8,35	N	0,46	N	0,96	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15419	15419	A	T	MI.9766	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	673	225	T	S	Aca/Tca	-3,26	0	0	probably_damaging	0,99	neutral	0,49	neutral	3,11	neutral	-0,66	neutral	0,47	neutral_impact	-0,33	neutral	0,96	neutral	0,83	neutral	-0,23	0,95	0,17	0,45	neutral	0,29	neutral	0,08	neutral	0,19	neutral	0,31	4	deleterious	0,99	neutral	0,25	neutral	-2	deleterious	0,66	low_impact	-2,59	medium_impact	0,21	low_impact	-1,49	0,63	0,8	57,11	8,35	N	0,49	N	0,79	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15419	15419	A	G	MI.9767	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	673	225	T	A	Aca/Gca	-3,26	0	0	probably_damaging	0,99	neutral	0,37	neutral	3,22	neutral	0,57	neutral	-1,31	medium_impact	2,77	neutral	0,98	neutral	0,53	neutral	1,77	14,82	0,1	0,4	neutral	0,38	disease	0,61	disease	0,65	disease	0,6	2	deleterious	0,99	neutral	0,19	deleterious	1	deleterious	0,73	low_impact	-2,59	medium_impact	0,1	medium_impact	1,32	0,35	0,8	57,11	8,35	N	0,38	N	0,6	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15420	15420	C	A	MI.9768	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	674	225	T	K	aCa/aAa	0,87	0,25	0	probably_damaging	1	neutral	0,29	neutral	3,05	neutral	-2,47	neutral	-2,1	high_impact	4,57	neutral	0,94	neutral	0,35	deleterious	4,3	24	0,04	0,35	neutral	0,49	disease	0,89	disease	0,75	disease	0,76	5	deleterious	1	neutral	0,15	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,01	high_impact	2,96	0,41	0,8	57,11	8,35	N	0,54	P	0,97	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15420	15420	C	T	MI.9769	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	674	225	T	M	aCa/aTa	0,87	0,25	0	probably_damaging	1	neutral	0,22	neutral	3,14	neutral	-0,26	deleterious	-2,61	medium_impact	3,21	neutral	0,94	neutral	0,43	deleterious	4,07	23,7	0,05	0,35	disease	0,54	disease	0,8	disease	0,51	disease	0,64	3	deleterious	1	neutral	0,11	deleterious	1	deleterious	0,76	low_impact	-3,53	medium_impact	-0,08	medium_impact	1,72	0,72	0,85	57,11	8,35	N	0,36	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8984	8984	C	T	MI.977	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	458	153	P	L	cCa/cTa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	3,98	neutral	-2,27	deleterious	-8,86	high_impact	3,79	damaging	0,55	damaging	0,03	deleterious	4,41	24,1	0,33	0,65	disease	0,83	disease	0,89	disease	0,71	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,85	low_impact	-3,6	low_impact	-1,4	high_impact	2,15	0,71	0,9	49,56	8,78	P	0,5	N	0,95	disease_causing	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15422	15422	A	C	MI.9770	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	676	226	I	L	Atc/Ctc	-4,64	0	0	benign	0,06	neutral	0,65	neutral	3,25	neutral	0,01	neutral	-0,22	low_impact	0,93	neutral	0,95	neutral	0,68	neutral	0,89	10,02	0,18	0,45	neutral	0,28	disease	0,68	neutral	0,17	neutral	0,39	2	neutral	0,27	deleterious	0,8	neutral	-6	neutral	0,16	medium_impact	0,38	medium_impact	0,37	medium_impact	-0,35	0,58	0,8	21,05	14,45	N	0,38	N	0,63	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15422	15422	A	T	MI.9771	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	676	226	I	F	Atc/Ttc	-4,64	0	0	possibly_damaging	0,58	neutral	0,7	neutral	3,12	neutral	-2,81	neutral	1,38	neutral_impact	0,68	neutral	0,97	neutral	0,67	deleterious	2,5	19,45	0,13	0,4	neutral	0,27	disease	0,73	neutral	0,17	neutral	0,42	2	neutral	0,5	deleterious	0,56	neutral	-3	deleterious	0,45	medium_impact	-0,86	medium_impact	0,42	medium_impact	-0,58	0,59	0,8	21,05	14,45	N	0,33	N	0,88	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15422	15422	A	G	MI.9772	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	676	226	I	V	Atc/Gtc	-4,64	0	0	benign	0	neutral	0,5	neutral	3,3	neutral	-1,53	neutral	-0,25	low_impact	1,48	neutral	0,97	neutral	0,77	deleterious	0,18	4,45	0,28	0,45	neutral	0,28	neutral	0,5	neutral	0,21	neutral	0,4	2	neutral	0,5	deleterious	0,75	neutral	-6	neutral	0,12	high_impact	2,07	medium_impact	0,22	medium_impact	0,15	0,34	0,8	21,05	14,45	N	0,37	N	0,51	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15423	15423	T	G	MI.9773	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	677	226	I	S	aTc/aGc	0,17	0	0	benign	0,36	neutral	0,41	neutral	3,08	neutral	-1,5	neutral	-1,77	medium_impact	2,38	neutral	0,94	neutral	0,4	deleterious	4,15	23,8	0,03	0,35	neutral	0,35	disease	0,83	neutral	0,28	disease	0,64	3	neutral	0,52	deleterious	0,53	neutral	-3	neutral	0,43	medium_impact	-0,5	medium_impact	0,14	medium_impact	0,97	0,28	0,8	21,05	14,45	N	0,33	N	0,88	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15423	15423	T	C	MI.9774	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	677	226	I	T	aTc/aCc	0,17	0	0	benign	0,01	neutral	0,39	neutral	3,09	neutral	-1,62	neutral	-1,36	low_impact	1,6	neutral	0,99	neutral	0,86	deleterious	2,06	16,58	0,09	0,35	neutral	0,42	disease	0,57	neutral	0,24	neutral	0,4	2	neutral	0,6	deleterious	0,69	neutral	-6	neutral	0,18	medium_impact	1,13	medium_impact	0,12	medium_impact	0,26	0,28	0,8	21,05	14,45	N	0,39	N	0,68	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15423	15423	T	A	MI.9775	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	677	226	I	N	aTc/aAc	0,17	0	0	possibly_damaging	0,62	neutral	0,31	neutral	3,08	neutral	-2,08	neutral	-2,15	medium_impact	2,79	neutral	0,93	neutral	0,41	deleterious	4,5	24,3	0,06	0,35	neutral	0,35	disease	0,9	neutral	0,47	disease	0,64	3	neutral	0,72	neutral	0,35	NA	0	deleterious	0,6	medium_impact	-0,93	medium_impact	0,03	medium_impact	1,34	0,19	0,8	21,05	14,45	N	0,37	N	1	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15424	15424	C	A	MI.9776	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	678	226	I	M	atC/atA	1,31	0	0	possibly_damaging	0,75	neutral	0,22	neutral	3,07	neutral	-2,7	neutral	-0,47	medium_impact	2,29	neutral	0,95	neutral	0,55	deleterious	3,59	23,2	0,18	0,45	disease	0,52	disease	0,63	neutral	0,21	neutral	0,42	2	neutral	0,85	neutral	0,24	NA	0	deleterious	0,52	low_impact	-1,18	medium_impact	-0,08	medium_impact	0,89	0,57	0,8	21,05	14,45	N	0,43	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15424	15424	C	G	MI.9777	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	678	226	I	M	atC/atG	1,31	0	0	possibly_damaging	0,75	neutral	0,22	neutral	3,07	neutral	-2,7	neutral	-0,47	medium_impact	2,29	neutral	0,95	neutral	0,55	deleterious	3,13	22,6	0,18	0,45	disease	0,52	disease	0,63	neutral	0,21	neutral	0,42	2	neutral	0,85	neutral	0,24	NA	0	deleterious	0,52	low_impact	-1,18	medium_impact	-0,08	medium_impact	0,89	0,57	0,8	21,05	14,45	N	0,43	N	0,77	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15425	15425	A	G	MI.9778	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	679	227	K	E	Aaa/Gaa	-9,46	0	0	possibly_damaging	0,46	neutral	0,27	neutral	2,86	neutral	-2,28	deleterious	-3,24	high_impact	4,69	neutral	0,73	damaging	0,13	deleterious	3,88	23,5	0,1	0,4	disease	0,6	disease	0,88	disease	0,77	disease	0,74	5	neutral	0,69	neutral	0,41	deleterious	1	deleterious	0,68	medium_impact	-0,67	medium_impact	-0,01	high_impact	3,07	0,42	0,8	57,89	8,77	P	0,61	P	0,95	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15425	15425	A	C	MI.9779	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	679	227	K	Q	Aaa/Caa	-9,46	0	0	benign	0,02	neutral	0,29	neutral	2,84	neutral	-2,97	deleterious	-3,23	high_impact	4,43	neutral	0,82	damaging	0,17	deleterious	3,18	22,7	0,19	0,45	disease	0,63	disease	0,83	disease	0,71	disease	0,72	4	neutral	0,7	deleterious	0,64	neutral	-2	neutral	0,31	medium_impact	0,85	medium_impact	0,01	high_impact	2,83	0,43	0,8	57,89	8,77	N	0,42	N	0,93	polymorphism	1	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8984	8984	C	G	MI.978	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	458	153	P	R	cCa/cGa	7,3	1	0	probably_damaging	1	deleterious	0,01	neutral	3,88	deleterious	-4,49	deleterious	-7,97	high_impact	4,49	neutral	0,61	damaging	0,04	deleterious	3,64	23,2	0,21	0,65	disease	0,82	disease	0,9	disease	0,8	disease	0,8	6	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,88	low_impact	-3,6	medium_impact	-0,84	high_impact	2,75	0,57	0,9	49,56	8,78	P	0,54	P	0,65	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15426	15426	A	C	MI.9780	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	680	227	K	T	aAa/aCa	6,81	1	0	possibly_damaging	0,8	neutral	0,39	neutral	2,82	deleterious	-3,75	deleterious	-4,85	high_impact	5,24	neutral	0,84	damaging	0,14	deleterious	3,72	23,3	0,05	0,35	disease	0,67	disease	0,83	disease	0,72	disease	0,71	4	neutral	0,81	neutral	0,3	deleterious	1	deleterious	0,78	low_impact	-1,29	medium_impact	0,12	high_impact	3,56	0,24	0,8	57,89	8,77	P	0,74	P	0,88	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15426	15426	A	T	MI.9781	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	680	227	K	M	aAa/aTa	6,81	1	0	probably_damaging	0,95	neutral	0,22	neutral	2,78	deleterious	-6,1	deleterious	-4,86	high_impact	4,89	neutral	0,85	damaging	0,15	deleterious	4,01	23,6	0,05	0,35	disease	0,83	disease	0,86	disease	0,71	disease	0,69	4	neutral	0,97	neutral	0,14	deleterious	2	deleterious	0,8	low_impact	-1,92	medium_impact	-0,08	high_impact	3,25	0,13	0,8	57,89	8,77	P	0,73	P	0,67	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15427	15427	A	T	MI.9782	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	681	227	K	N	aaA/aaT	8,42	1	0	possibly_damaging	0,74	neutral	0,31	neutral	2,84	neutral	-2,94	deleterious	-4,05	high_impact	4,55	neutral	0,82	damaging	0,13	deleterious	3,9	23,5	0,17	0,45	disease	0,55	disease	0,86	disease	0,72	disease	0,72	4	neutral	0,79	neutral	0,29	deleterious	1	deleterious	0,77	low_impact	-1,16	medium_impact	0,03	high_impact	2,94	0,29	0,8	57,89	8,77	P	0,64	P	0,84	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15427	15427	A	C	MI.9783	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	681	227	K	N	aaA/aaC	8,42	1	0	possibly_damaging	0,74	neutral	0,31	neutral	2,84	neutral	-2,94	deleterious	-4,05	high_impact	4,55	neutral	0,82	damaging	0,13	deleterious	3,82	23,4	0,17	0,45	disease	0,55	disease	0,86	disease	0,72	disease	0,72	4	neutral	0,79	neutral	0,29	deleterious	1	deleterious	0,77	low_impact	-1,16	medium_impact	0,03	high_impact	2,94	0,29	0,8	57,89	8,77	P	0,62	P	0,84	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15428	15428	G	A	MI.9784	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	682	228	D	N	Gac/Aac	1,31	1	0	probably_damaging	1	neutral	0,31	neutral	3,02	deleterious	-3,15	deleterious	-4,04	high_impact	5,07	neutral	0,88	damaging	0,13	deleterious	4,26	23,9	0,34	0,5	neutral	0,47	disease	0,86	disease	0,7	disease	0,72	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,03	high_impact	3,41	0,71	0,85	56,58	8,57	P	0,67	P	0,99	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15428	15428	G	T	MI.9785	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	682	228	D	Y	Gac/Tac	1,31	1	0	probably_damaging	1	neutral	1	neutral	2,96	deleterious	-5,52	deleterious	-7,27	high_impact	5,62	neutral	0,92	damaging	0,11	deleterious	3,97	23,6	0,02	0,35	disease	0,92	disease	0,94	disease	0,75	disease	0,74	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,9	low_impact	-3,53	high_impact	1,85	high_impact	3,91	0,06	0,8	56,58	8,57	P	0,62	P	1	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15428	15428	G	C	MI.9786	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	682	228	D	H	Gac/Cac	1,31	1	0	probably_damaging	1	neutral	0,54	neutral	2,97	deleterious	-4,55	deleterious	-5,66	high_impact	5,27	neutral	0,91	damaging	0,1	deleterious	3,65	23,2	0,05	0,35	disease	0,85	disease	0,89	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,26	high_impact	3,59	0,3	0,8	56,58	8,57	P	0,67	P	1	polymorphism	1	0,5	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15429	15429	A	C	MI.9787	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	683	228	D	A	gAc/gCc	5,9	1	0	probably_damaging	1	neutral	0,5	neutral	3,05	deleterious	-3,25	deleterious	-6,47	high_impact	5,62	neutral	0,93	damaging	0,13	deleterious	3,58	23,2	0,04	0,35	disease	0,73	disease	0,83	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,22	high_impact	3,91	0,17	0,8	56,58	8,57	P	0,7	P	0,95	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15429	15429	A	T	MI.9788	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	683	228	D	V	gAc/gTc	5,9	1	0	probably_damaging	1	neutral	0,5	neutral	2,98	deleterious	-4,64	deleterious	-7,27	high_impact	5,27	neutral	0,92	damaging	0,12	deleterious	3,72	23,3	0,02	0,35	disease	0,87	disease	0,92	disease	0,71	disease	0,73	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,22	high_impact	3,59	0,04	0,8	56,58	8,57	P	0,71	P	1	polymorphism	1	0,51	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15429	15429	A	G	MI.9789	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	683	228	D	G	gAc/gGc	5,9	1	0	probably_damaging	1	neutral	0,33	neutral	2,99	deleterious	-3,94	deleterious	-5,66	high_impact	4,3	neutral	0,92	damaging	0,14	deleterious	3,95	23,6	0,04	0,35	disease	0,77	disease	0,88	disease	0,68	disease	0,72	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	0,06	high_impact	2,71	0,2	0,8	56,58	8,57	P	0,6	P	1	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8984	8984	C	A	MI.979	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	458	153	P	Q	cCa/cAa	7,3	1	0	probably_damaging	1	deleterious	0	neutral	3,88	deleterious	-4,48	deleterious	-7,08	high_impact	4,49	damaging	0,58	damaging	0,04	deleterious	4,23	23,9	0,22	0,65	disease	0,8	disease	0,87	disease	0,72	disease	0,76	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,84	low_impact	-3,6	low_impact	-1,4	high_impact	2,75	0,51	0,9	49,56	8,78	N	0,47	N	0,82	disease_causing	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15430	15430	C	G	MI.9790	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	684	228	D	E	gaC/gaG	6,59	1	0	probably_damaging	0,99	neutral	0,27	neutral	3,05	neutral	-2,27	deleterious	-3,23	high_impact	4,72	neutral	0,91	damaging	0,13	deleterious	3,57	23,2	0,13	0,4	neutral	0,46	disease	0,82	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	-0,01	high_impact	3,09	0,36	0,8	56,58	8,57	P	0,69	P	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15430	15430	C	A	MI.9791	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	684	228	D	E	gaC/gaA	6,59	1	0	probably_damaging	0,99	neutral	0,27	neutral	3,05	neutral	-2,27	deleterious	-3,23	high_impact	4,72	neutral	0,91	damaging	0,13	deleterious	3,92	23,5	0,13	0,4	neutral	0,46	disease	0,82	disease	0,64	disease	0,67	3	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	-0,01	high_impact	3,09	0,36	0,8	56,58	8,57	P	0,7	P	1	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15431	15431	G	C	MI.9792	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	685	229	A	P	Gcc/Ccc	-1,44	0	0,01	possibly_damaging	0,71	neutral	0,2	neutral	3,1	neutral	-2,19	neutral	-1,76	medium_impact	2,29	neutral	0,94	neutral	0,39	deleterious	3,83	23,4	0,04	0,35	disease	0,66	disease	0,83	disease	0,68	disease	0,78	6	neutral	0,84	neutral	0,25	NA	0	deleterious	0,65	low_impact	-1,09	medium_impact	-0,1	medium_impact	0,89	0,54	0,8	20	21,64	N	0,36	N	0,38	polymorphism	1	0,08	rs193302993	Likely pathogenic	Neoplasm_of_ovary	RCV000133455.1	Gene:MedGen:OMIM:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	15431	15431	G	A	MI.9793	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	685	229	A	T	Gcc/Acc	-1,44	0	0,01	benign	0,18	neutral	0,4	neutral	3,19	neutral	-0,39	neutral	-0,22	low_impact	1,1	neutral	0,97	neutral	0,74	deleterious	3,07	22,4	0,16	0,45	neutral	0,38	neutral	0,3	neutral	0,26	neutral	0,47	1	neutral	0,52	deleterious	0,61	neutral	-6	neutral	0,15	medium_impact	-0,12	medium_impact	0,13	medium_impact	-0,2	0,58	0,8	20	21,64	N	0,51	P	0,12	polymorphism	1	0,01	rs527236208,rs193302993	Likely pathogenic	Neoplasm_of_ovary	RCV000133455.1	Gene:MedGen:OMIM:SNOMED_CT	.	.	.	2,97	.	.	.	.	.	.
chrM	15431	15431	G	T	MI.9794	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	685	229	A	S	Gcc/Tcc	-1,44	0	0,01	benign	0,3	neutral	0,41	neutral	3,14	neutral	1,88	neutral	-0,9	low_impact	1,25	neutral	0,95	neutral	0,69	deleterious	3,49	23,1	0,24	0,45	neutral	0,43	neutral	0,4	disease	0,52	neutral	0,48	0	neutral	0,51	deleterious	0,56	neutral	-6	neutral	0,22	medium_impact	-0,39	medium_impact	0,14	medium_impact	-0,06	0,44	0,8	20	21,64	N	0,37	N	0,22	polymorphism	1	0,02	rs193302993	Likely pathogenic	Neoplasm_of_ovary	RCV000133455.1	Gene:MedGen:OMIM:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	15432	15432	C	T	MI.9795	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	686	229	A	V	gCc/gTc	-1,44	0	0	benign	0,01	neutral	0,54	neutral	3,23	neutral	0,61	neutral	1,64	neutral_impact	0,53	neutral	0,98	neutral	0,94	deleterious	3,34	22,9	0,14	0,4	neutral	0,22	neutral	0,48	neutral	0,28	neutral	0,43	1	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,1	medium_impact	1,13	medium_impact	0,26	medium_impact	-0,71	0,63	0,8	20	21,64	N	0,33	N	0,01	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15432	15432	C	G	MI.9796	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	686	229	A	G	gCc/gGc	-1,44	0	0	benign	0,37	neutral	0,36	neutral	3,21	neutral	-1,59	neutral	-2,37	medium_impact	2,06	neutral	0,93	neutral	0,59	deleterious	3,85	23,4	0,18	0,45	neutral	0,4	neutral	0,46	disease	0,52	disease	0,51	0	neutral	0,58	deleterious	0,5	neutral	-3	neutral	0,24	medium_impact	-0,52	medium_impact	0,09	medium_impact	0,68	0,58	0,8	20	21,64	N	0,36	N	0,4	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15432	15432	C	A	MI.9797	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	686	229	A	D	gCc/gAc	-1,44	0	0	possibly_damaging	0,62	neutral	0,3	neutral	3,1	neutral	-2,17	neutral	-2,29	medium_impact	3,1	neutral	0,92	neutral	0,47	deleterious	4,51	24,3	0,03	0,35	disease	0,72	disease	0,78	disease	0,68	disease	0,76	5	neutral	0,73	neutral	0,34	NA	0	deleterious	0,44	medium_impact	-0,93	medium_impact	0,02	medium_impact	1,62	0,33	0,8	20	21,64	N	0,35	N	0,36	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15434	15434	C	T	MI.9798	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	688	230	L	F	Ctc/Ttc	-3,96	0	0	probably_damaging	1	neutral	0,62	neutral	3,02	deleterious	-4,05	neutral	-2,46	low_impact	1,68	neutral	0,84	neutral	0,65	deleterious	3,91	23,5	0,18	0,45	neutral	0,45	disease	0,59	neutral	0,33	neutral	0,35	3	deleterious	1	neutral	0,31	neutral	-2	deleterious	0,71	low_impact	-3,53	medium_impact	0,34	medium_impact	0,33	0,66	0,8	47,63	8,12	N	0,2	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15434	15434	C	A	MI.9799	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	688	230	L	I	Ctc/Atc	-3,96	0	0	probably_damaging	1	neutral	0,67	neutral	3,02	neutral	-2,32	neutral	-1,2	medium_impact	2,64	neutral	0,77	neutral	0,46	deleterious	3,93	23,5	0,33	0,5	neutral	0,34	disease	0,55	neutral	0,31	neutral	0,39	2	deleterious	1	neutral	0,34	deleterious	1	deleterious	0,68	low_impact	-3,53	medium_impact	0,39	medium_impact	1,2	0,52	0,8	47,63	8,12	N	0,22	N	0,83	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8570	8570	T	G	MI.98	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	44	15	L	R	cTa/cGa	-1,49	0	0	probably_damaging	1	deleterious	0,03	neutral	4,4	deleterious	-3,68	deleterious	-4,3	medium_impact	3,48	neutral	0,8	damaging	0,16	deleterious	3,93	23,5	0,19	0,65	disease	0,81	disease	0,9	disease	0,77	disease	0,85	7	deleterious	1	neutral	0,02	deleterious	5	deleterious	0,88	low_impact	-3,6	medium_impact	-0,56	medium_impact	1,89	0,74	0,9	11,5	26,27	N	0,34	N	0,85	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8986	8986	A	C	MI.980	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	460	154	M	L	Ata/Cta	-10,28	0	0	benign	0	neutral	1	neutral	4,89	neutral	2,35	neutral	0,02	neutral_impact	-1,8	neutral	0,87	neutral	0,95	neutral	-1,16	0,01	0,44	0,65	disease	0,54	neutral	0,17	neutral	0,36	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,13	high_impact	2,09	high_impact	1,98	low_impact	-2,64	0,7	0,9	15,49	11,76	N	0,37	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15434	15434	C	G	MI.9800	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	688	230	L	V	Ctc/Gtc	-3,96	0	0	probably_damaging	0,99	neutral	0,54	neutral	3	neutral	-0,76	neutral	-1,83	low_impact	1,42	neutral	0,82	neutral	0,5	deleterious	3,04	22,4	0,26	0,45	neutral	0,21	neutral	0,45	neutral	0,29	neutral	0,41	2	deleterious	0,99	neutral	0,28	neutral	-2	deleterious	0,66	low_impact	-2,59	medium_impact	0,26	medium_impact	0,1	0,51	0,8	47,63	8,12	N	0,26	N	0,88	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15435	15435	T	A	MI.9801	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	689	230	L	H	cTc/cAc	-0,52	0	0	probably_damaging	1	neutral	0,33	neutral	2,88	deleterious	-5,71	deleterious	-4,89	high_impact	5,06	neutral	0,82	neutral	0,33	deleterious	4,15	23,8	0,06	0,35	disease	0,76	disease	0,79	disease	0,69	disease	0,69	4	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,06	high_impact	3,4	0,23	0,8	47,63	8,12	P	0,67	P	0,95	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15435	15435	T	G	MI.9802	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	689	230	L	R	cTc/cGc	-0,52	0	0	probably_damaging	1	neutral	0,21	neutral	2,9	deleterious	-4,95	deleterious	-4,29	high_impact	5,06	neutral	0,84	neutral	0,32	deleterious	4,18	23,8	0,03	0,35	disease	0,69	disease	0,88	disease	0,73	disease	0,74	5	deleterious	1	neutral	0,11	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,09	high_impact	3,4	0,22	0,8	47,63	8,12	P	0,7	P	0,99	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15435	15435	T	C	MI.9803	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	689	230	L	P	cTc/cCc	-0,52	0	0	probably_damaging	1	neutral	0,12	neutral	2,91	deleterious	-5,58	deleterious	-4,96	high_impact	4,25	neutral	0,83	neutral	0,29	deleterious	3,93	23,5	0,03	0,35	disease	0,75	disease	0,82	disease	0,73	disease	0,71	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,25	high_impact	2,67	0,23	0,8	47,63	8,12	N	0,4	N	0,99	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15437	15437	G	C	MI.9804	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	691	231	G	R	Ggc/Cgc	-0,75	0	0	probably_damaging	1	neutral	0,24	neutral	3,04	neutral	-2,83	deleterious	-6,12	high_impact	5,12	neutral	0,79	damaging	0,22	deleterious	3,88	23,5	0,03	0,35	disease	0,55	disease	0,89	disease	0,83	disease	0,77	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,85	low_impact	-3,53	medium_impact	-0,05	high_impact	3,46	0,54	0,8	57,37	8,89	P	0,69	P	0,99	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15437	15437	G	A	MI.9805	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	691	231	G	S	Ggc/Agc	-0,75	0	0	probably_damaging	1	neutral	0,31	neutral	3,06	neutral	-1,87	deleterious	-4,51	high_impact	3,84	neutral	0,87	neutral	0,34	deleterious	4,18	23,8	0,08	0,35	neutral	0,4	disease	0,78	disease	0,65	disease	0,68	4	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	0,03	high_impact	2,29	0,68	0,85	57,37	8,89	N	0,37	N	0,99	polymorphism	1	0,19	rs878853058	Uncertain significance	not_provided	RCV000224435.1	MedGen	.	.	.	.	.	.	.	.	.	.
chrM	15437	15437	G	T	MI.9806	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	691	231	G	C	Ggc/Tgc	-0,75	0	0	probably_damaging	1	neutral	0,19	neutral	3,04	neutral	-2,4	deleterious	-6,87	high_impact	4,57	neutral	0,79	damaging	0,22	deleterious	4,15	23,8	0,04	0,35	disease	0,78	disease	0,86	disease	0,72	disease	0,71	4	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,12	high_impact	2,96	0,14	0,8	57,37	8,89	N	0,42	N	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15438	15438	G	T	MI.9807	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	692	231	G	V	gGc/gTc	7,27	1	0	probably_damaging	1	neutral	0,44	neutral	3,14	neutral	-0,6	deleterious	-6,84	high_impact	4,02	neutral	0,79	neutral	0,35	deleterious	3,82	23,4	0,04	0,35	neutral	0,44	disease	0,86	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,17	high_impact	2,46	0,11	0,8	57,37	8,89	P	0,55	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15438	15438	G	C	MI.9808	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	692	231	G	A	gGc/gCc	7,27	1	0	probably_damaging	1	neutral	0,4	neutral	3,09	neutral	-1,16	deleterious	-4,53	high_impact	4,08	neutral	0,7	neutral	0,41	deleterious	3,15	22,6	0,1	0,4	neutral	0,41	disease	0,65	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,13	high_impact	2,51	0,31	0,8	57,37	8,89	P	0,59	P	0,84	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15438	15438	G	A	MI.9809	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	692	231	G	D	gGc/gAc	7,27	1	0	probably_damaging	1	neutral	0,19	neutral	3,02	deleterious	-3,96	deleterious	-5,36	high_impact	4,92	neutral	0,72	damaging	0,28	deleterious	3,84	23,4	0,03	0,35	disease	0,59	disease	0,88	disease	0,82	disease	0,76	5	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	-0,12	high_impact	3,27	0,08	0,8	57,37	8,89	P	0,77	P	1	polymorphism	1	0,4	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8986	8986	A	T	MI.981	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	460	154	M	L	Ata/Tta	-10,28	0	0	benign	0	neutral	1	neutral	4,89	neutral	2,35	neutral	0,02	neutral_impact	-1,8	neutral	0,87	neutral	0,95	neutral	-1,02	0,01	0,44	0,65	disease	0,54	neutral	0,17	neutral	0,36	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,13	high_impact	2,09	high_impact	1,98	low_impact	-2,64	0,7	0,9	15,49	11,76	N	0,38	N	0,1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15440	15440	T	A	MI.9810	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	694	232	L	M	Tta/Ata	-14,5	0	0,04	benign	0,09	neutral	0,27	neutral	3,1	neutral	-0,68	neutral	-0,26	neutral_impact	0,6	neutral	0,89	neutral	0,9	deleterious	2,22	17,63	0,23	0,45	neutral	0,42	neutral	0,38	neutral	0,21	neutral	0,47	1	neutral	0,7	deleterious	0,59	neutral	-6	neutral	0,17	medium_impact	0,21	medium_impact	-0,01	medium_impact	-0,65	0,54	0,8	19,74	19,02	N	0,49	N	0,52	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15440	15440	T	G	MI.9811	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	694	232	L	V	Tta/Gta	-14,5	0	0,04	benign	0,09	neutral	0,58	neutral	3,21	neutral	0,19	neutral	-0,57	neutral_impact	0,54	neutral	0,96	neutral	0,96	neutral	-0,15	1,4	0,19	0,45	neutral	0,19	neutral	0,32	neutral	0,23	neutral	0,44	1	neutral	0,33	deleterious	0,75	neutral	-6	neutral	0,15	medium_impact	0,21	medium_impact	0,3	medium_impact	-0,7	0,57	0,8	19,74	19,02	N	0,38	N	0,09	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15441	15441	T	G	MI.9812	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	695	232	L	W	tTa/tGa	-3,96	0	0	probably_damaging	0,96	neutral	0,2	neutral	3,02	deleterious	-3,49	neutral	-0,93	medium_impact	2,48	neutral	0,84	neutral	0,45	deleterious	3,79	23,4	0,06	0,35	disease	0,54	disease	0,74	neutral	0,41	disease	0,51	0	neutral	0,98	neutral	0,12	deleterious	1	deleterious	0,73	low_impact	-2,02	medium_impact	-0,1	medium_impact	1,06	0,19	0,8	19,74	19,02	N	0,34	N	0,6	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15441	15441	T	C	MI.9813	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	695	232	L	S	tTa/tCa	-3,96	0	0	possibly_damaging	0,77	neutral	0,4	neutral	3,13	neutral	-0,42	neutral	-1,82	medium_impact	2,21	neutral	0,89	neutral	0,62	deleterious	3,64	23,2	0,07	0,35	neutral	0,45	disease	0,54	disease	0,51	disease	0,54	1	neutral	0,78	neutral	0,32	NA	0	deleterious	0,66	low_impact	-1,22	medium_impact	0,13	medium_impact	0,81	0,21	0,8	19,74	19,02	N	0,33	N	0,3	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15442	15442	A	T	MI.9814	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	696	232	L	F	ttA/ttT	0,86	0	0,01	possibly_damaging	0,44	neutral	1	neutral	3,3	neutral	0,87	neutral	1,97	neutral_impact	-1,52	neutral	0,92	neutral	0,88	deleterious	0,59	8,08	0,21	0,45	neutral	0,25	neutral	0,05	neutral	0,17	neutral	0,22	6	neutral	0,44	deleterious	0,78	neutral	-3	deleterious	0,48	medium_impact	-0,63	high_impact	1,85	low_impact	-2,57	0,51	0,8	19,74	19,02	N	0,33	N	0,42	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15442	15442	A	C	MI.9815	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	696	232	L	F	ttA/ttC	0,86	0	0,01	possibly_damaging	0,44	neutral	1	neutral	3,3	neutral	0,87	neutral	1,97	neutral_impact	-1,52	neutral	0,92	neutral	0,88	deleterious	0,46	7,13	0,21	0,45	neutral	0,25	neutral	0,05	neutral	0,17	neutral	0,22	6	neutral	0,44	deleterious	0,78	neutral	-3	deleterious	0,48	medium_impact	-0,63	high_impact	1,85	low_impact	-2,57	0,51	0,8	19,74	19,02	N	0,32	N	0,42	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15443	15443	C	A	MI.9816	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	697	233	L	I	Ctt/Att	-10,83	0	0	benign	0,36	neutral	0,64	neutral	2,98	neutral	-1,07	neutral	0,16	neutral_impact	0,06	neutral	0,94	neutral	0,96	deleterious	2,12	16,97	0,27	0,45	neutral	0,36	neutral	0,12	neutral	0,18	neutral	0,29	4	neutral	0,3	deleterious	0,64	neutral	-6	neutral	0,14	medium_impact	-0,5	medium_impact	0,36	low_impact	-1,14	0,45	0,8	27,11	30,06	N	0,45	N	0,04	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15443	15443	C	T	MI.9817	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	697	233	L	F	Ctt/Ttt	-10,83	0	0	benign	0,03	neutral	1	neutral	2,97	neutral	-1,12	neutral	-1,23	low_impact	0,93	neutral	0,98	neutral	0,94	deleterious	2,52	19,57	0,22	0,45	neutral	0,25	neutral	0,33	neutral	0,3	neutral	0,44	1	neutral	0,03	deleterious	0,99	neutral	-6	neutral	0,1	medium_impact	0,68	high_impact	1,85	medium_impact	-0,35	0,5	0,8	27,11	30,06	N	0,33	N	0,09	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15443	15443	C	G	MI.9818	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	697	233	L	V	Ctt/Gtt	-10,83	0	0	benign	0,17	neutral	0,53	neutral	2,99	neutral	-1,01	neutral	0,22	neutral_impact	0,59	neutral	0,96	neutral	0,94	neutral	1,63	14	0,25	0,45	neutral	0,26	neutral	0,17	neutral	0,23	neutral	0,27	5	neutral	0,37	deleterious	0,68	neutral	-6	neutral	0,11	medium_impact	-0,09	medium_impact	0,25	medium_impact	-0,66	0,63	0,8	27,11	30,06	N	0,39	N	0,06	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15444	15444	T	A	MI.9819	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	698	233	L	H	cTt/cAt	-10,6	0	0	probably_damaging	0,93	neutral	0,22	neutral	2,84	deleterious	-4,38	deleterious	-2,87	high_impact	4	neutral	0,93	neutral	0,45	deleterious	4,21	23,9	0,07	0,35	disease	0,75	disease	0,58	disease	0,65	disease	0,68	4	neutral	0,95	neutral	0,15	deleterious	2	deleterious	0,68	low_impact	-1,78	medium_impact	-0,08	high_impact	2,44	0,17	0,8	27,11	30,06	N	0,46	N	0,57	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8986	8986	A	G	MI.982	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	460	154	M	V	Ata/Gta	-10,28	0	0	benign	0	neutral	0,22	neutral	4,5	neutral	2,22	neutral	-0,79	neutral_impact	0,03	neutral	0,96	neutral	0,98	neutral	-0,44	0,3	0,48	0,65	neutral	0,29	neutral	0,42	neutral	0,45	neutral	0,45	1	neutral	0,78	deleterious	0,61	neutral	-6	neutral	0,15	high_impact	2,09	medium_impact	-0,02	low_impact	-1,07	0,75	0,9	15,49	11,76	N	0,37	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15444	15444	T	C	MI.9820	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	698	233	L	P	cTt/cCt	-10,6	0	0	probably_damaging	0,94	neutral	0,08	neutral	2,84	deleterious	-4,07	deleterious	-2,64	medium_impact	3,45	neutral	0,93	neutral	0,33	deleterious	3,93	23,5	0,03	0,35	disease	0,76	disease	0,8	disease	0,7	disease	0,73	5	deleterious	0,98	neutral	0,07	deleterious	1	deleterious	0,78	low_impact	-1,85	medium_impact	-0,35	medium_impact	1,94	0,31	0,8	27,11	30,06	N	0,39	N	0,79	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15444	15444	T	G	MI.9821	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	698	233	L	R	cTt/cGt	-10,6	0	0	possibly_damaging	0,78	neutral	0,14	neutral	2,85	deleterious	-3,83	deleterious	-2,53	high_impact	4	neutral	0,94	neutral	0,42	deleterious	4,21	23,9	0,03	0,35	disease	0,68	disease	0,79	disease	0,69	disease	0,72	4	neutral	0,91	neutral	0,18	deleterious	1	deleterious	0,65	low_impact	-1,24	medium_impact	-0,21	high_impact	2,44	0,21	0,8	27,11	30,06	N	0,44	N	0,62	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15446	15446	C	G	MI.9822	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	700	234	L	V	Ctc/Gtc	-11,75	0	0	probably_damaging	0,98	neutral	0,71	neutral	3,15	neutral	-0,26	neutral	-0,48	neutral_impact	0,47	neutral	0,93	neutral	0,82	deleterious	0,41	6,71	0,25	0,45	neutral	0,28	neutral	0,15	neutral	0,22	neutral	0,28	4	neutral	0,97	neutral	0,37	neutral	-2	deleterious	0,61	low_impact	-2,31	medium_impact	0,43	medium_impact	-0,77	0,63	0,8	20	21,38	N	0,35	N	0,36	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15446	15446	C	T	MI.9823	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	700	234	L	F	Ctc/Ttc	-11,75	0	0	probably_damaging	1	neutral	0,78	neutral	3	neutral	-1,91	neutral	-1,7	low_impact	1,46	neutral	0,94	neutral	0,92	deleterious	2,47	19,25	0,19	0,45	neutral	0,3	neutral	0,3	neutral	0,28	neutral	0,45	1	deleterious	1	neutral	0,39	neutral	-2	deleterious	0,63	low_impact	-3,53	medium_impact	0,52	medium_impact	0,13	0,45	0,8	20	21,38	N	0,26	N	0,19	polymorphism	1	0,04	rs1057518823	Uncertain significance|Uncertain significance	Focal_white_matter_lesions|Ischemic_stroke	RCV000415336.1|RCV000415336.1	Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen	.	.	.	.	.	.	.	.	.	.
chrM	15446	15446	C	A	MI.9824	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	700	234	L	I	Ctc/Atc	-11,75	0	0	probably_damaging	0,99	neutral	0,87	neutral	3,18	neutral	0,05	neutral	-0,08	neutral_impact	-0,33	neutral	0,91	neutral	0,96	neutral	1,56	13,65	0,27	0,45	neutral	0,21	neutral	0,07	neutral	0,15	neutral	0,22	6	deleterious	0,99	neutral	0,44	neutral	-2	deleterious	0,59	low_impact	-2,59	medium_impact	0,67	low_impact	-1,49	0,4	0,8	20	21,38	N	0,42	N	0,08	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15447	15447	T	G	MI.9825	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	701	234	L	R	cTc/cGc	-8,08	0	0	probably_damaging	1	neutral	0,07	neutral	2,96	deleterious	-3,5	deleterious	-3,56	high_impact	4,21	neutral	0,84	neutral	0,48	deleterious	4,13	23,8	0,02	0,35	disease	0,62	disease	0,8	disease	0,68	disease	0,73	5	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,39	high_impact	2,63	0,25	0,8	20	21,38	N	0,41	N	0,89	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15447	15447	T	C	MI.9826	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	701	234	L	P	cTc/cCc	-8,08	0	0	probably_damaging	1	deleterious	0,04	neutral	2,95	deleterious	-4,09	deleterious	-3,88	high_impact	4,21	neutral	0,78	neutral	0,37	deleterious	3,85	23,4	0,02	0,35	disease	0,52	disease	0,8	disease	0,67	disease	0,73	5	deleterious	1	neutral	0,02	deleterious	6	deleterious	0,79	low_impact	-3,53	medium_impact	-0,53	high_impact	2,63	0,28	0,8	20	21,38	N	0,36	N	0,93	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15447	15447	T	A	MI.9827	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	701	234	L	H	cTc/cAc	-8,08	0	0	probably_damaging	1	neutral	0,12	neutral	2,95	deleterious	-4,05	deleterious	-3,89	high_impact	4,21	neutral	0,82	neutral	0,49	deleterious	4,08	23,7	0,05	0,35	neutral	0,4	disease	0,6	disease	0,63	disease	0,7	4	deleterious	1	neutral	0,06	deleterious	2	deleterious	0,69	low_impact	-3,53	medium_impact	-0,25	high_impact	2,63	0,24	0,8	20	21,38	N	0,44	N	0,76	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15449	15449	T	C	MI.9828	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	703	235	F	L	Ttc/Ctc	-10,15	0	0	benign	0	neutral	1	neutral	3,24	neutral	-1,43	neutral	1,51	neutral_impact	-0,88	neutral	0,99	neutral	0,96	neutral	-0,25	0,87	0,12	0,4	neutral	0,21	neutral	0,16	neutral	0,25	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,07	high_impact	1,85	low_impact	-1,99	0,22	0,8	16,32	18,6	N	0,36	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15449	15449	T	A	MI.9829	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	703	235	F	I	Ttc/Atc	-10,15	0	0	benign	0,08	neutral	0,61	neutral	3,14	neutral	-1,64	neutral	0,7	low_impact	1,05	neutral	0,95	neutral	0,72	deleterious	3,11	22,5	0,15	0,45	neutral	0,27	neutral	0,38	neutral	0,35	neutral	0,44	1	neutral	0,31	deleterious	0,77	neutral	-6	neutral	0,11	medium_impact	0,26	medium_impact	0,33	medium_impact	-0,24	0,35	0,8	16,32	18,6	N	0,33	N	0,26	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8987	8987	T	C	MI.983	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	461	154	M	T	aTa/aCa	-5,89	0	0	benign	0,07	deleterious	0,01	neutral	4,43	neutral	-0,1	deleterious	-3,02	medium_impact	2,11	neutral	0,92	neutral	0,7	neutral	1,2	11,76	0,41	0,65	neutral	0,47	neutral	0,48	disease	0,62	disease	0,58	2	deleterious	0,99	deleterious	0,47	deleterious	1	neutral	0,24	medium_impact	0,31	medium_impact	-0,84	medium_impact	0,71	0,43	0,9	15,49	11,76	N	0,4	N	0,58	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15449	15449	T	G	MI.9830	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	703	235	F	V	Ttc/Gtc	-10,15	0	0	benign	0,12	neutral	0,35	neutral	3,22	neutral	-1,56	neutral	0,41	low_impact	1,2	neutral	0,98	neutral	0,81	deleterious	3,76	23,4	0,13	0,4	neutral	0,25	neutral	0,43	neutral	0,36	neutral	0,43	1	neutral	0,59	deleterious	0,62	neutral	-6	neutral	0,13	medium_impact	0,08	medium_impact	0,08	medium_impact	-0,1	0,21	0,8	16,32	18,6	N	0,43	N	0,36	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15450	15450	T	G	MI.9831	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	704	235	F	C	tTc/tGc	-3,27	0	0	possibly_damaging	0,84	neutral	0,08	neutral	3,02	deleterious	-4,68	neutral	-1,19	medium_impact	3,04	neutral	0,94	neutral	0,45	deleterious	4,1	23,7	0,08	0,35	disease	0,66	disease	0,58	neutral	0,5	neutral	0,47	1	neutral	0,96	neutral	0,12	NA	0	deleterious	0,63	low_impact	-1,4	medium_impact	-0,35	medium_impact	1,57	0,17	0,8	16,32	18,6	N	0,45	N	0,56	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15450	15450	T	A	MI.9832	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	704	235	F	Y	tTc/tAc	-3,27	0	0	benign	0,37	neutral	0,22	neutral	3,04	neutral	-2,77	neutral	-0,88	medium_impact	2,58	neutral	0,95	neutral	0,63	deleterious	2,74	21	0,15	0,4	neutral	0,4	neutral	0,33	disease	0,57	neutral	0,49	0	neutral	0,74	neutral	0,43	neutral	-3	neutral	0,29	medium_impact	-0,52	medium_impact	-0,08	medium_impact	1,15	0,41	0,8	16,32	18,6	N	0,44	N	0,35	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15450	15450	T	C	MI.9833	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	704	235	F	S	tTc/tCc	-3,27	0	0	benign	0,37	neutral	0,09	neutral	3,06	deleterious	-3,33	neutral	-1,41	medium_impact	2,53	neutral	0,93	neutral	0,53	deleterious	4,06	23,7	0,08	0,35	neutral	0,29	neutral	0,44	disease	0,57	neutral	0,5	0	neutral	0,9	neutral	0,36	neutral	-3	neutral	0,35	medium_impact	-0,52	medium_impact	-0,32	medium_impact	1,1	0,34	0,8	16,32	18,6	N	0,44	N	0,59	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15451	15451	C	A	MI.9834	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	705	235	F	L	ttC/ttA	1,77	0,01	0	benign	0	neutral	1	neutral	3,24	neutral	-1,43	neutral	1,51	neutral_impact	-0,88	neutral	0,99	neutral	0,96	deleterious	0,45	7,05	0,12	0,4	neutral	0,21	neutral	0,16	neutral	0,25	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,07	high_impact	1,85	low_impact	-1,99	0,22	0,8	16,32	18,6	N	0,34	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15451	15451	C	G	MI.9835	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	705	235	F	L	ttC/ttG	1,77	0,01	0	benign	0	neutral	1	neutral	3,24	neutral	-1,43	neutral	1,51	neutral_impact	-0,88	neutral	0,99	neutral	0,96	deleterious	0,12	3,86	0,12	0,4	neutral	0,21	neutral	0,16	neutral	0,25	neutral	0,26	5	neutral	0	deleterious	1	neutral	-6	neutral	0,09	high_impact	2,07	high_impact	1,85	low_impact	-1,99	0,22	0,8	16,32	18,6	N	0,31	N	0	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15452	15452	C	A	MI.9836	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	706	236	L	I	Ctt/Att	-0,75	0	0,39	benign	0,22	neutral	0,54	neutral	3,15	neutral	-1,51	neutral	-0,79	neutral_impact	0,68	neutral	0,96	neutral	0,95	deleterious	0,64	8,43	0,24	0,45	neutral	0,36	neutral	0,17	neutral	0,25	neutral	0,28	4	neutral	0,35	deleterious	0,66	neutral	-6	neutral	0,15	medium_impact	-0,22	medium_impact	0,26	medium_impact	-0,58	0,38	0,8	16,84	18,89	N	0,36	N	0,11	polymorphism	1	0,03	rs193302994,rs527236209	Likely pathogenic	Neoplasm_of_ovary	RCV000133456.1	Gene:MedGen:OMIM:SNOMED_CT	.	.	.	5,05	.	.	.	.	.	.
chrM	15452	15452	C	G	MI.9837	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	706	236	L	V	Ctt/Gtt	-0,75	0	0,39	benign	0,09	neutral	0,4	neutral	3,11	neutral	-1,31	neutral	-1,43	medium_impact	2,56	neutral	0,91	neutral	0,75	neutral	1,59	13,78	0,22	0,45	neutral	0,36	neutral	0,36	neutral	0,33	neutral	0,46	1	neutral	0,54	deleterious	0,66	neutral	-3	neutral	0,14	medium_impact	0,21	medium_impact	0,13	medium_impact	1,13	0,51	0,8	16,84	18,89	N	0,41	N	0,38	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15452	15452	C	T	MI.9838	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	706	236	L	F	Ctt/Ttt	-0,75	0	0,39	benign	0,01	neutral	1	neutral	3,01	neutral	-1,91	neutral	-2,24	low_impact	1,29	neutral	0,9	neutral	0,95	deleterious	2,44	19,11	0,21	0,45	disease	0,57	neutral	0,38	neutral	0,31	disease	0,59	2	neutral	0,01	deleterious	1	neutral	-6	neutral	0,13	medium_impact	1,13	high_impact	1,85	medium_impact	-0,02	0,43	0,8	16,84	18,89	N	0,26	N	0,21	polymorphism	1	0,11	rs193302994	Likely pathogenic	Neoplasm_of_ovary	RCV000133456.1	Gene:MedGen:OMIM:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	15453	15453	T	C	MI.9839	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	707	236	L	P	cTt/cCt	-2,12	0	0	probably_damaging	0,94	neutral	0,14	neutral	2,89	deleterious	-4,84	deleterious	-4,66	high_impact	4,46	neutral	0,83	neutral	0,38	deleterious	3,81	23,4	0,03	0,35	disease	0,82	disease	0,8	disease	0,7	disease	0,73	5	neutral	0,97	neutral	0,1	deleterious	2	deleterious	0,81	low_impact	-1,85	medium_impact	-0,21	high_impact	2,86	0,29	0,8	16,84	18,89	P	0,52	P	0,95	polymorphism	1	0,36	rs527236184	Likely pathogenic	Neoplasm_of_ovary	RCV000133428.1	Gene:MedGen:OMIM:SNOMED_CT	.	.	.	.	T15453C	Isolated complex III deficiency	+	-	Reported	1
chrM	8987	8987	T	A	MI.984	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	461	154	M	K	aTa/aAa	-5,89	0	0	benign	0,13	deleterious	0,01	neutral	4,37	neutral	-1,68	deleterious	-3,95	medium_impact	2,11	neutral	0,84	neutral	0,4	deleterious	2,52	19,57	0,27	0,65	disease	0,73	disease	0,74	disease	0,69	disease	0,75	5	deleterious	0,99	neutral	0,44	deleterious	1	neutral	0,37	medium_impact	0,03	medium_impact	-0,84	medium_impact	0,71	0,57	0,9	15,49	11,76	N	0,29	N	0,78	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15453	15453	T	A	MI.9840	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	707	236	L	H	cTt/cAt	-2,12	0	0	probably_damaging	0,91	neutral	0,25	neutral	2,9	deleterious	-4,79	deleterious	-4,6	high_impact	4,81	neutral	0,82	neutral	0,49	deleterious	4,08	23,7	0,05	0,35	disease	0,82	disease	0,73	disease	0,66	disease	0,71	4	neutral	0,93	neutral	0,17	deleterious	2	deleterious	0,74	low_impact	-1,67	medium_impact	-0,04	high_impact	3,17	0,24	0,8	16,84	18,89	P	0,65	P	0,77	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15453	15453	T	G	MI.9841	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	707	236	L	R	cTt/cGt	-2,12	0	0	possibly_damaging	0,82	neutral	0,16	neutral	2,9	deleterious	-4,24	deleterious	-4,08	high_impact	4,81	neutral	0,84	neutral	0,49	deleterious	4,04	23,7	0,03	0,35	disease	0,76	disease	0,85	disease	0,69	disease	0,72	4	neutral	0,91	neutral	0,17	deleterious	1	deleterious	0,76	low_impact	-1,35	medium_impact	-0,17	high_impact	3,17	0,24	0,8	16,84	18,89	P	0,67	P	0,89	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15455	15455	C	G	MI.9842	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	709	237	L	V	Ctc/Gtc	-10,83	0	0	benign	0,32	neutral	0,34	neutral	3,14	neutral	-0,92	neutral	-0,62	low_impact	1,63	neutral	0,91	neutral	0,72	deleterious	1,94	15,84	0,3	0,45	neutral	0,34	neutral	0,19	neutral	0,28	neutral	0,38	2	neutral	0,59	deleterious	0,51	neutral	-6	neutral	0,18	medium_impact	-0,43	medium_impact	0,07	medium_impact	0,29	0,37	0,8	21,58	16,91	N	0,46	N	0,6	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15455	15455	C	T	MI.9843	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	709	237	L	F	Ctc/Ttc	-10,83	0	0	benign	0,06	neutral	0,59	neutral	3,09	neutral	-1,47	neutral	-1,45	neutral_impact	0,62	neutral	0,9	neutral	0,87	deleterious	2,66	20,5	0,24	0,45	disease	0,52	neutral	0,24	neutral	0,26	neutral	0,36	3	neutral	0,34	deleterious	0,77	neutral	-6	neutral	0,13	medium_impact	0,38	medium_impact	0,31	medium_impact	-0,63	0,41	0,8	21,58	16,91	N	0,34	N	0,31	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15455	15455	C	A	MI.9844	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	709	237	L	I	Ctc/Atc	-10,83	0	0	possibly_damaging	0,56	neutral	0,57	neutral	3,25	neutral	-0,35	neutral	-0,33	low_impact	0,88	neutral	0,89	neutral	0,91	deleterious	2,57	19,93	0,28	0,45	neutral	0,26	neutral	0,16	neutral	0,23	neutral	0,29	4	neutral	0,51	deleterious	0,51	neutral	-3	neutral	0,21	medium_impact	-0,83	medium_impact	0,29	medium_impact	-0,39	0,35	0,8	21,58	16,91	N	0,41	N	0,5	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15456	15456	T	G	MI.9845	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	710	237	L	R	cTc/cGc	-5,79	0	0,01	probably_damaging	0,95	neutral	0,05	neutral	3,01	deleterious	-3,8	deleterious	-2,81	high_impact	3,66	neutral	0,82	neutral	0,51	deleterious	4,11	23,7	0,04	0,35	disease	0,72	disease	0,74	disease	0,58	disease	0,67	3	deleterious	0,99	neutral	0,05	deleterious	2	deleterious	0,77	low_impact	-1,92	medium_impact	-0,47	high_impact	2,13	0,23	0,8	21,58	16,91	N	0,37	N	0,99	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15456	15456	T	C	MI.9846	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	710	237	L	P	cTc/cCc	-5,79	0	0,01	probably_damaging	0,99	neutral	0,09	neutral	3	deleterious	-4,04	deleterious	-3,21	medium_impact	3,17	neutral	0,91	neutral	0,38	deleterious	3,82	23,4	0,03	0,35	disease	0,79	disease	0,74	disease	0,66	disease	0,72	4	deleterious	0,99	neutral	0,05	deleterious	1	deleterious	0,8	low_impact	-2,59	medium_impact	-0,32	medium_impact	1,69	0,24	0,8	21,58	16,91	N	0,39	N	0,96	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15456	15456	T	A	MI.9847	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	710	237	L	H	cTc/cAc	-5,79	0	0,01	probably_damaging	0,98	neutral	0,08	neutral	3	deleterious	-4,37	deleterious	-3,25	high_impact	4,21	neutral	0,82	neutral	0,48	deleterious	4,06	23,7	0,07	0,35	disease	0,78	disease	0,57	disease	0,53	disease	0,58	2	deleterious	0,99	neutral	0,05	deleterious	2	deleterious	0,73	low_impact	-2,31	medium_impact	-0,35	high_impact	2,63	0,13	0,8	21,58	16,91	N	0,45	N	0,91	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15458	15458	T	G	MI.9848	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	712	238	S	A	Tcc/Gcc	-8,31	0	0	benign	0	neutral	0,6	neutral	3,25	neutral	1,51	neutral	0,86	neutral_impact	-1,09	neutral	0,98	neutral	0,97	neutral	-0,47	0,26	0,26	0,45	neutral	0,15	neutral	0,04	neutral	0,23	neutral	0,22	6	neutral	0,39	deleterious	0,8	neutral	-6	neutral	0,06	high_impact	2,07	medium_impact	0,32	low_impact	-2,18	0,39	0,8	4,74	11,93	N	0,41	N	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15458	15458	T	A	MI.9849	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	712	238	S	T	Tcc/Acc	-8,31	0	0	benign	0	neutral	0,29	neutral	3,2	neutral	0,8	neutral	0,21	neutral_impact	-0,42	neutral	0,98	neutral	0,97	deleterious	0,21	4,77	0,27	0,45	neutral	0,26	neutral	0,07	neutral	0,23	neutral	0,23	5	neutral	0,71	deleterious	0,65	neutral	-6	neutral	0,07	high_impact	2,07	medium_impact	0,01	low_impact	-1,58	0,4	0,8	4,74	11,93	N	0,54	P	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8988	8988	A	T	MI.985	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	462	154	M	I	atA/atT	5,68	0,89	0	benign	0,02	neutral	0,55	neutral	4,57	neutral	1,84	neutral	-0,48	neutral_impact	-1	neutral	0,91	neutral	0,96	deleterious	0,33	6,01	0,42	0,65	neutral	0,28	neutral	0,28	neutral	0,4	neutral	0,42	2	neutral	0,42	deleterious	0,77	neutral	-6	neutral	0,15	medium_impact	0,85	medium_impact	0,34	low_impact	-1,95	0,82	0,9	15,49	11,76	N	0,46	N	0,06	polymorphism	0,95	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15458	15458	T	C	MI.9850	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	712	238	S	P	Tcc/Ccc	-8,31	0	0	benign	0,29	neutral	0,23	neutral	3,14	neutral	-1,53	neutral	-1,07	low_impact	1,38	neutral	0,97	neutral	0,72	deleterious	2,32	18,31	0,08	0,35	neutral	0,38	disease	0,6	neutral	0,4	neutral	0,24	5	neutral	0,72	deleterious	0,47	neutral	-6	neutral	0,22	medium_impact	-0,37	medium_impact	-0,06	medium_impact	0,06	0,31	0,8	4,74	11,93	P	0,57	P	0,22	polymorphism	1	0,03	rs527236185	Likely pathogenic	Familial_cancer_of_breast	RCV000133429.1	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	.	.	.	.	.	.	.	.
chrM	15459	15459	C	T	MI.9851	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	713	238	S	F	tCc/tTc	-9,69	0	0	benign	0,17	neutral	0,6	neutral	3,19	neutral	0,62	neutral	-0,62	neutral_impact	-0,34	neutral	0,97	neutral	0,94	neutral	1,76	14,77	0,08	0,35	neutral	0,23	neutral	0,35	neutral	0,29	neutral	0,44	1	neutral	0,29	deleterious	0,72	neutral	-6	neutral	0,12	medium_impact	-0,09	medium_impact	0,32	low_impact	-1,5	0,3	0,8	4,74	11,93	N	0,33	N	0,06	polymorphism	1	0,02	rs527236186	Likely pathogenic	Neoplasm_of_ovary	RCV000133430.1	Gene:MedGen:OMIM:SNOMED_CT	.	.	.	0,3	.	.	.	.	.	.
chrM	15459	15459	C	G	MI.9852	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	713	238	S	C	tCc/tGc	-9,69	0	0	possibly_damaging	0,68	neutral	0,09	neutral	3,14	neutral	-1,31	neutral	-0,37	neutral_impact	0,76	neutral	0,93	neutral	0,76	deleterious	2,25	17,81	0,1	0,4	disease	0,54	neutral	0,38	neutral	0,29	disease	0,55	1	neutral	0,92	neutral	0,21	neutral	-3	neutral	0,33	low_impact	-1,04	medium_impact	-0,32	medium_impact	-0,5	0,32	0,8	4,74	11,93	N	0,48	N	0,15	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15459	15459	C	A	MI.9853	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	713	238	S	Y	tCc/tAc	-9,69	0	0	possibly_damaging	0,49	neutral	0,61	neutral	3,17	neutral	-0,06	neutral	-0,98	low_impact	1,73	neutral	0,95	neutral	0,66	neutral	1,35	12,55	0,09	0,35	neutral	0,41	neutral	0,36	neutral	0,38	neutral	0,45	1	neutral	0,43	deleterious	0,56	neutral	-3	neutral	0,22	medium_impact	-0,72	medium_impact	0,33	medium_impact	0,38	0,28	0,8	4,74	11,93	N	0,3	N	0,06	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15461	15461	T	G	MI.9854	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	715	239	L	V	Tta/Gta	-12,21	0	0	probably_damaging	0,99	neutral	0,26	neutral	2,95	neutral	-1,44	neutral	-2,31	high_impact	3,82	neutral	0,84	neutral	0,55	deleterious	3,19	22,7	0,29	0,45	neutral	0,4	neutral	0,33	disease	0,66	neutral	0,45	1	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,67	low_impact	-2,59	medium_impact	-0,02	high_impact	2,28	0,44	0,8	48,95	8,77	N	0,45	N	0,88	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15461	15461	T	A	MI.9855	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	715	239	L	M	Tta/Ata	-12,21	0	0	probably_damaging	1	neutral	0,3	neutral	2,86	neutral	-2,47	neutral	-1,53	medium_impact	2,94	neutral	0,88	neutral	0,61	deleterious	3,62	23,2	0,24	0,45	disease	0,59	neutral	0,36	disease	0,55	disease	0,55	1	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,69	low_impact	-3,53	medium_impact	0,02	medium_impact	1,48	0,48	0,8	48,95	8,77	N	0,41	N	0,94	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15462	15462	T	C	MI.9856	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	716	239	L	S	tTa/tCa	0,17	0	0	probably_damaging	1	neutral	0,26	neutral	2,82	deleterious	-3,3	deleterious	-4,63	high_impact	4,91	neutral	0,77	neutral	0,51	deleterious	3,79	23,4	0,05	0,35	disease	0,57	neutral	0,5	disease	0,66	disease	0,64	3	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,72	low_impact	-3,53	medium_impact	-0,02	high_impact	3,26	0,31	0,8	48,95	8,77	P	0,67	P	0,97	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15462	15462	T	G	MI.9857	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	716	239	L	W	tTa/tGa	0,17	0	0	probably_damaging	1	neutral	0,06	neutral	2,79	deleterious	-5,49	deleterious	-4,63	high_impact	4,91	neutral	0,84	neutral	0,43	deleterious	3,78	23,4	0,05	0,35	disease	0,84	disease	0,53	disease	0,69	disease	0,7	4	deleterious	1	neutral	0,03	deleterious	2	deleterious	0,74	low_impact	-3,53	medium_impact	-0,43	high_impact	3,26	0,22	0,8	48,95	8,77	P	0,66	P	1	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15463	15463	A	C	MI.9858	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	717	239	L	F	ttA/ttC	5,67	0,94	0	probably_damaging	1	neutral	0,41	neutral	2,96	neutral	-1,07	deleterious	-2,98	low_impact	1,56	neutral	0,92	neutral	0,71	deleterious	2,33	18,37	0,19	0,45	neutral	0,23	neutral	0,34	neutral	0,43	neutral	0,39	2	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,66	low_impact	-3,53	medium_impact	0,14	medium_impact	0,22	0,5	0,8	48,95	8,77	P	0,52	P	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15463	15463	A	T	MI.9859	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	717	239	L	F	ttA/ttT	5,67	0,94	0	probably_damaging	1	neutral	0,41	neutral	2,96	neutral	-1,07	deleterious	-2,98	low_impact	1,56	neutral	0,92	neutral	0,71	deleterious	2,47	19,3	0,19	0,45	neutral	0,23	neutral	0,34	neutral	0,43	neutral	0,39	2	deleterious	1	neutral	0,21	neutral	-2	deleterious	0,66	low_impact	-3,53	medium_impact	0,14	medium_impact	0,22	0,5	0,8	48,95	8,77	P	0,53	P	0,97	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8988	8988	A	C	MI.986	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	462	154	M	I	atA/atC	5,68	0,89	0	benign	0,02	neutral	0,55	neutral	4,57	neutral	1,84	neutral	-0,48	neutral_impact	-1	neutral	0,91	neutral	0,96	deleterious	0,17	4,35	0,42	0,65	neutral	0,28	neutral	0,28	neutral	0,4	neutral	0,42	2	neutral	0,42	deleterious	0,77	neutral	-6	neutral	0,15	medium_impact	0,85	medium_impact	0,34	low_impact	-1,95	0,82	0,9	15,49	11,76	N	0,46	N	0,06	polymorphism	0,95	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15464	15464	A	T	MI.9860	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	718	240	M	L	Atg/Ttg	-12,21	0	0	probably_damaging	0,93	neutral	1	neutral	3,24	neutral	0,72	neutral	-0,11	neutral_impact	-0,44	neutral	0,98	neutral	0,96	neutral	-1,16	0,01	0,25	0,45	neutral	0,19	neutral	0,18	neutral	0,28	neutral	0,32	4	neutral	0,93	deleterious	0,54	neutral	-2	deleterious	0,55	low_impact	-1,78	high_impact	1,85	low_impact	-1,59	0,3	0,8	16,32	18,46	N	0,36	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15464	15464	A	C	MI.9861	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	718	240	M	L	Atg/Ctg	-12,21	0	0	probably_damaging	0,93	neutral	1	neutral	3,24	neutral	0,72	neutral	-0,11	neutral_impact	-0,44	neutral	0,98	neutral	0,96	neutral	-1,14	0,01	0,25	0,45	neutral	0,19	neutral	0,18	neutral	0,28	neutral	0,32	4	neutral	0,93	deleterious	0,54	neutral	-2	deleterious	0,55	low_impact	-1,78	high_impact	1,85	low_impact	-1,59	0,3	0,8	16,32	18,46	N	0,35	N	0,2	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15464	15464	A	G	MI.9862	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	718	240	M	V	Atg/Gtg	-12,21	0	0	probably_damaging	0,96	neutral	0,4	neutral	3,26	neutral	0,76	neutral	-0,13	neutral_impact	0,76	neutral	0,98	neutral	0,57	neutral	-0,11	1,62	0,23	0,45	neutral	0,23	neutral	0,22	neutral	0,36	neutral	0,39	2	neutral	0,96	neutral	0,22	neutral	-2	deleterious	0,58	low_impact	-2,02	medium_impact	0,13	medium_impact	-0,5	0,27	0,8	16,32	18,46	N	0,42	N	0,69	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15465	15465	T	A	MI.9863	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	719	240	M	K	aTg/aAg	-3,5	0	0	probably_damaging	0,98	neutral	0,11	neutral	3,08	neutral	-2,28	neutral	-1,89	medium_impact	3,42	neutral	0,93	neutral	0,4	deleterious	2,38	18,67	0,05	0,35	neutral	0,49	disease	0,55	disease	0,61	disease	0,66	3	deleterious	0,99	neutral	0,07	deleterious	1	deleterious	0,69	low_impact	-2,31	medium_impact	-0,27	medium_impact	1,91	0,2	0,8	16,32	18,46	N	0,43	N	0,87	disease_causing	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15465	15465	T	C	MI.9864	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	719	240	M	T	aTg/aCg	-3,5	0	0	probably_damaging	0,99	neutral	0,35	neutral	3,13	neutral	-0,75	neutral	0,24	neutral_impact	0,42	neutral	0,99	neutral	0,97	neutral	-0,38	0,44	0,13	0,4	neutral	0,25	neutral	0,09	neutral	0,35	neutral	0,27	5	deleterious	0,99	neutral	0,18	neutral	-2	deleterious	0,62	low_impact	-2,59	medium_impact	0,08	medium_impact	-0,81	0,18	0,8	16,32	18,46	N	0,54	P	0,75	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15466	15466	G	T	MI.9865	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	720	240	M	I	atG/atT	0,4	0	0	probably_damaging	0,97	neutral	0,42	neutral	3,33	neutral	1,35	neutral	-0,34	neutral_impact	0,38	neutral	0,95	neutral	0,65	deleterious	0,61	8,25	0,24	0,45	neutral	0,16	neutral	0,2	neutral	0,29	neutral	0,36	3	neutral	0,97	neutral	0,23	neutral	-2	deleterious	0,58	low_impact	-2,14	medium_impact	0,15	medium_impact	-0,85	0,27	0,8	16,32	18,46	N	0,37	N	0,56	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15466	15466	G	C	MI.9866	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	720	240	M	I	atG/atC	0,4	0	0	probably_damaging	0,97	neutral	0,42	neutral	3,33	neutral	1,35	neutral	-0,34	neutral_impact	0,38	neutral	0,95	neutral	0,65	deleterious	0,45	7,05	0,24	0,45	neutral	0,16	neutral	0,2	neutral	0,29	neutral	0,36	3	neutral	0,97	neutral	0,23	neutral	-2	deleterious	0,58	low_impact	-2,14	medium_impact	0,15	medium_impact	-0,85	0,27	0,8	16,32	18,46	N	0,37	N	0,56	disease_causing	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15467	15467	A	C	MI.9867	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	721	241	T	P	Aca/Cca	-5,79	0	0	benign	0,09	neutral	0,24	neutral	3,1	neutral	-2,42	neutral	-2,16	medium_impact	2,96	neutral	0,98	neutral	0,39	deleterious	2,05	16,56	0,08	0,35	disease	0,65	disease	0,67	disease	0,58	disease	0,67	3	neutral	0,73	deleterious	0,58	neutral	-3	neutral	0,25	medium_impact	0,21	medium_impact	-0,05	medium_impact	1,49	0,46	0,8	16,05	16,67	N	0,36	N	0,88	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15467	15467	A	T	MI.9868	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	721	241	T	S	Aca/Tca	-5,79	0	0	benign	0	neutral	0,45	neutral	3,15	neutral	-0,47	neutral	0	neutral_impact	-0,1	neutral	0,98	neutral	0,97	neutral	-1,03	0,01	0,35	0,5	neutral	0,33	neutral	0,06	neutral	0,24	neutral	0,23	5	neutral	0,55	deleterious	0,73	neutral	-6	neutral	0,07	high_impact	2,07	medium_impact	0,18	low_impact	-1,28	0,68	0,85	16,05	16,67	N	0,53	P	0,02	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15467	15467	A	G	MI.9869	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	721	241	T	A	Aca/Gca	-5,79	0	0	benign	0	neutral	0,23	neutral	3,31	neutral	1,46	neutral	-0,64	low_impact	1,15	neutral	0,96	neutral	0,8	deleterious	0,05	3,09	0,19	0,45	neutral	0,33	neutral	0,13	neutral	0,27	neutral	0,27	5	neutral	0,77	deleterious	0,62	neutral	-6	neutral	0,08	high_impact	2,07	medium_impact	-0,06	medium_impact	-0,15	0,4	0,8	16,05	16,67	N	0,47	N	0,17	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8989	8989	G	A	MI.987	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	463	155	A	T	Gcc/Acc	-2,88	0	0,01	probably_damaging	1	neutral	0,79	neutral	4,21	neutral	1,51	deleterious	-3,22	low_impact	1,27	neutral	0,82	neutral	0,47	deleterious	4,3	24	0,36	0,65	neutral	0,47	disease	0,55	neutral	0,44	neutral	0,44	1	deleterious	1	neutral	0,4	neutral	-2	deleterious	0,74	low_impact	-3,6	medium_impact	0,62	medium_impact	-0,01	0,75	0,9	44,25	8,13	N	0,21	N	0,8	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15468	15468	C	A	MI.9870	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	722	241	T	K	aCa/aAa	-6,48	0	0	benign	0,02	neutral	0,14	neutral	3,11	neutral	-1,78	neutral	-1,66	medium_impact	3,1	neutral	0,94	neutral	0,46	neutral	1,68	14,27	0,08	0,35	disease	0,55	disease	0,53	disease	0,55	disease	0,63	3	neutral	0,86	deleterious	0,56	neutral	-3	neutral	0,17	medium_impact	0,85	medium_impact	-0,21	medium_impact	1,62	0,51	0,8	16,05	16,67	N	0,37	N	0,74	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15468	15468	C	T	MI.9871	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	722	241	T	M	aCa/aTa	-6,48	0	0	possibly_damaging	0,56	neutral	0,38	neutral	3,18	neutral	0,13	neutral	-0,81	neutral_impact	0,34	neutral	0,93	neutral	0,92	deleterious	2,7	20,8	0,12	0,4	neutral	0,44	neutral	0,24	neutral	0,25	neutral	0,46	1	neutral	0,63	neutral	0,41	neutral	-3	deleterious	0,48	medium_impact	-0,83	medium_impact	0,11	medium_impact	-0,89	0,65	0,8	16,05	16,67	N	0,44	N	0,71	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15470	15470	T	G	MI.9872	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	724	242	L	V	Tta/Gta	-4,19	0	0	probably_damaging	0,99	neutral	0,44	neutral	2,94	neutral	-0,93	neutral	-2,06	medium_impact	2	neutral	0,96	damaging	0,13	deleterious	3,03	22,3	0,21	0,45	neutral	0,37	neutral	0,31	neutral	0,42	neutral	0,41	2	deleterious	0,99	neutral	0,23	deleterious	1	deleterious	0,66	low_impact	-2,59	medium_impact	0,17	medium_impact	0,62	0,49	0,8	57,37	8,45	N	0,31	N	0,88	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15470	15470	T	A	MI.9873	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	724	242	L	M	Tta/Ata	-4,19	0	0	probably_damaging	1	neutral	0,3	neutral	2,83	deleterious	-3,24	neutral	-1,43	medium_impact	2,92	neutral	0,95	damaging	0,19	deleterious	3,58	23,2	0,18	0,45	neutral	0,47	neutral	0,33	neutral	0,39	neutral	0,4	2	deleterious	1	neutral	0,15	deleterious	1	deleterious	0,67	low_impact	-3,53	medium_impact	0,02	medium_impact	1,46	0,58	0,8	57,37	8,45	N	0,4	N	0,94	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15471	15471	T	G	MI.9874	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	725	242	L	W	tTa/tGa	-0,75	0	0	probably_damaging	1	neutral	0,08	neutral	2,78	deleterious	-4,63	deleterious	-4,59	high_impact	4,08	neutral	0,95	damaging	0,1	deleterious	3,77	23,4	0,04	0,35	disease	0,56	disease	0,54	disease	0,69	disease	0,64	3	deleterious	1	neutral	0,04	deleterious	2	deleterious	0,71	low_impact	-3,53	medium_impact	-0,35	high_impact	2,51	0,26	0,8	57,37	8,45	N	0,44	N	1	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15471	15471	T	C	MI.9875	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	725	242	L	S	tTa/tCa	-0,75	0	0	probably_damaging	1	neutral	0,25	neutral	2,83	deleterious	-3,28	deleterious	-4,52	high_impact	4,16	neutral	0,93	damaging	0,1	deleterious	3,76	23,3	0,03	0,35	disease	0,55	neutral	0,5	disease	0,66	disease	0,64	3	deleterious	1	neutral	0,13	deleterious	2	deleterious	0,73	low_impact	-3,53	medium_impact	-0,04	high_impact	2,58	0,34	0,8	57,37	8,45	N	0,44	N	0,97	polymorphism	1	0,18	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15472	15472	A	T	MI.9876	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	726	242	L	F	ttA/ttT	3,61	0,36	0	probably_damaging	1	neutral	0,65	neutral	2,92	neutral	-1,64	deleterious	-2,94	medium_impact	2,01	neutral	0,97	neutral	0,43	deleterious	3,49	23,1	0,13	0,4	neutral	0,28	neutral	0,4	neutral	0,44	neutral	0,4	2	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,66	low_impact	-3,53	medium_impact	0,37	medium_impact	0,63	0,53	0,8	57,37	8,45	N	0,31	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15472	15472	A	C	MI.9877	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	726	242	L	F	ttA/ttC	3,61	0,36	0	probably_damaging	1	neutral	0,65	neutral	2,92	neutral	-1,64	deleterious	-2,94	medium_impact	2,01	neutral	0,97	neutral	0,43	deleterious	3,4	23	0,13	0,4	neutral	0,28	neutral	0,4	neutral	0,44	neutral	0,4	2	deleterious	1	neutral	0,33	deleterious	1	deleterious	0,66	low_impact	-3,53	medium_impact	0,37	medium_impact	0,63	0,53	0,8	57,37	8,45	N	0,31	N	0,97	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15473	15473	A	T	MI.9878	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	727	243	T	S	Aca/Tca	-0,29	0	0	benign	0,4	neutral	0,43	neutral	3,19	neutral	-0,49	neutral	-0,05	neutral_impact	-0,52	neutral	0,84	neutral	0,63	neutral	1,76	14,75	0,35	0,5	neutral	0,22	neutral	0,19	neutral	0,29	neutral	0,34	3	neutral	0,51	deleterious	0,52	neutral	-6	neutral	0,21	medium_impact	-0,57	medium_impact	0,16	low_impact	-1,67	0,64	0,8	22,89	25,04	N	0,35	N	0,19	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15473	15473	A	G	MI.9879	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	727	243	T	A	Aca/Gca	-0,29	0	0	benign	0,17	neutral	0,57	neutral	3,35	neutral	0,77	neutral	0,9	neutral_impact	-0,7	neutral	0,87	neutral	0,82	neutral	0,98	10,56	0,23	0,45	neutral	0,2	neutral	0,06	neutral	0,28	neutral	0,17	7	neutral	0,32	deleterious	0,7	neutral	-6	neutral	0,1	medium_impact	-0,09	medium_impact	0,29	low_impact	-1,83	0,27	0,8	22,89	25,04	N	0,35	N	0,05	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8989	8989	G	T	MI.988	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	463	155	A	S	Gcc/Tcc	-2,88	0	0,01	probably_damaging	0,99	neutral	0,29	neutral	4,34	neutral	1,91	deleterious	-2,51	low_impact	1,34	neutral	0,66	neutral	0,51	deleterious	3,74	23,3	0,34	0,65	neutral	0,28	disease	0,75	neutral	0,46	neutral	0,5	0	deleterious	0,99	neutral	0,15	neutral	-2	deleterious	0,73	low_impact	-2,65	medium_impact	0,07	medium_impact	0,05	0,86	0,9	44,25	8,13	N	0,35	N	0,95	disease_causing	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15473	15473	A	C	MI.9880	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	727	243	T	P	Aca/Cca	-0,29	0	0	possibly_damaging	0,79	neutral	0,22	neutral	3,06	neutral	-2,24	neutral	-1,78	high_impact	3,52	neutral	0,84	neutral	0,45	deleterious	3,38	22,9	0,06	0,35	disease	0,59	disease	0,76	disease	0,71	disease	0,75	5	neutral	0,87	neutral	0,22	deleterious	1	deleterious	0,61	low_impact	-1,27	medium_impact	-0,08	high_impact	2	0,42	0,8	22,89	25,04	N	0,32	N	0,8	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15474	15474	C	A	MI.9881	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	728	243	T	K	aCa/aAa	0,17	0	0	possibly_damaging	0,52	neutral	0,2	neutral	3,07	neutral	-1,96	neutral	-1,65	high_impact	3,52	neutral	0,84	neutral	0,55	deleterious	4,3	24	0,09	0,35	neutral	0,43	disease	0,64	disease	0,69	disease	0,71	4	neutral	0,78	neutral	0,34	deleterious	1	neutral	0,42	medium_impact	-0,76	medium_impact	-0,1	high_impact	2	0,44	0,8	22,89	25,04	N	0,38	N	0,77	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15474	15474	C	T	MI.9882	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	728	243	T	M	aCa/aTa	0,17	0	0	possibly_damaging	0,8	neutral	0,2	neutral	3,09	neutral	-0,84	neutral	-1,39	low_impact	1,89	neutral	0,83	neutral	0,57	deleterious	3,94	23,5	0,12	0,4	neutral	0,4	neutral	0,47	disease	0,59	disease	0,53	1	neutral	0,88	neutral	0,2	neutral	-3	deleterious	0,45	low_impact	-1,29	medium_impact	-0,1	medium_impact	0,52	0,55	0,8	22,89	25,04	N	0,36	N	0,51	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15476	15476	C	G	MI.9883	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	730	244	L	V	Cta/Gta	-6,48	0	0	probably_damaging	0,99	neutral	0,45	neutral	3,03	neutral	-0,86	neutral	-2,26	medium_impact	3,19	neutral	0,94	damaging	0,13	deleterious	3,18	22,7	0,38	0,5	neutral	0,34	neutral	0,36	disease	0,67	neutral	0,44	1	deleterious	0,99	neutral	0,23	deleterious	1	deleterious	0,66	low_impact	-2,59	medium_impact	0,18	medium_impact	1,7	0,46	0,8	56,84	8,68	N	0,32	N	0,73	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15476	15476	C	A	MI.9884	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	730	244	L	M	Cta/Ata	-6,48	0	0	probably_damaging	1	neutral	0,28	neutral	2,91	neutral	-2,55	neutral	-1,45	medium_impact	2,28	neutral	0,96	damaging	0,25	deleterious	2,66	20,6	0,28	0,45	disease	0,54	neutral	0,29	neutral	0,4	neutral	0,41	2	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,68	low_impact	-3,53	medium_impact	0	medium_impact	0,88	0,49	0,8	56,84	8,68	N	0,4	N	0,26	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15477	15477	T	A	MI.9885	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	731	244	L	Q	cTa/cAa	-1,21	0	0	probably_damaging	1	neutral	0,2	neutral	2,99	neutral	-2,92	deleterious	-4,57	high_impact	3,94	neutral	0,94	damaging	0,07	deleterious	4,28	24	0,04	0,35	disease	0,7	disease	0,65	disease	0,67	disease	0,66	3	deleterious	1	neutral	0,1	deleterious	2	deleterious	0,75	low_impact	-3,53	medium_impact	-0,1	high_impact	2,38	0,21	0,8	56,84	8,68	N	0,4	N	0,93	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15477	15477	T	C	MI.9886	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	731	244	L	P	cTa/cCa	-1,21	0	0	probably_damaging	1	neutral	0,23	neutral	2,9	deleterious	-3,09	deleterious	-5,35	high_impact	4,59	neutral	0,94	damaging	0,06	deleterious	4,01	23,6	0,02	0,35	disease	0,76	disease	0,66	disease	0,78	disease	0,72	4	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,06	high_impact	2,97	0,12	0,8	56,84	8,68	N	0,52	P	0,92	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15477	15477	T	G	MI.9887	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	731	244	L	R	cTa/cGa	-1,21	0	0	probably_damaging	1	neutral	0,24	neutral	2,9	deleterious	-3,67	deleterious	-4,59	high_impact	5,14	neutral	0,94	damaging	0,06	deleterious	4,18	23,8	0,02	0,35	disease	0,68	disease	0,79	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,12	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	-0,05	high_impact	3,47	0,19	0,8	56,84	8,68	P	0,71	P	0,99	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15479	15479	T	G	MI.9888	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	733	245	F	V	Ttc/Gtc	-0,06	0,83	0,01	possibly_damaging	0,61	neutral	0,52	neutral	3,07	neutral	-0,83	deleterious	-4,34	high_impact	3,73	neutral	0,95	neutral	0,5	deleterious	4,05	23,7	0,11	0,4	neutral	0,39	disease	0,69	disease	0,67	disease	0,65	3	neutral	0,58	neutral	0,46	deleterious	1	deleterious	0,46	medium_impact	-0,91	medium_impact	0,24	high_impact	2,19	0,28	0,8	21,58	15,99	N	0,37	N	0,78	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15479	15479	T	A	MI.9889	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	733	245	F	I	Ttc/Atc	-0,06	0,83	0,01	benign	0,29	neutral	0,43	neutral	3,28	neutral	0,49	deleterious	-3,59	medium_impact	2,64	neutral	0,94	neutral	0,48	deleterious	4,3	24	0,19	0,45	neutral	0,34	disease	0,61	neutral	0,43	neutral	0,44	1	neutral	0,48	deleterious	0,57	neutral	-3	neutral	0,39	medium_impact	-0,37	medium_impact	0,16	medium_impact	1,2	0,47	0,8	21,58	15,99	N	0,34	N	0,65	polymorphism	1	0,09	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8989	8989	G	C	MI.989	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	463	155	A	P	Gcc/Ccc	-2,88	0	0,01	probably_damaging	1	deleterious	0	neutral	3,72	deleterious	-3,85	deleterious	-4,39	high_impact	3,94	damaging	0,59	neutral	0,44	deleterious	3,86	23,5	0,15	0,65	disease	0,92	disease	0,93	disease	0,76	disease	0,86	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,6	low_impact	-1,4	high_impact	2,28	0,76	0,9	44,25	8,13	N	0,37	N	0,97	disease_causing_automatic	1	0,3	rs587776444	Pathogenic	Leigh_syndrome	RCV000144025.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	CPD	0,15	.	.	.	.	.	.
chrM	15479	15479	T	C	MI.9890	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	733	245	F	L	Ttc/Ctc	-0,06	0,83	0,01	benign	0,02	neutral	0,79	neutral	3,13	neutral	-0,33	deleterious	-3,39	low_impact	1,48	neutral	0,96	neutral	0,58	deleterious	2,7	20,8	0,25	0,45	neutral	0,4	disease	0,5	neutral	0,37	neutral	0,39	2	neutral	0,17	deleterious	0,89	neutral	-6	neutral	0,17	medium_impact	0,85	medium_impact	0,53	medium_impact	0,15	0,66	0,8	21,58	15,99	N	0,2	N	0,08	polymorphism	1	0,08	rs202008188	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15480	15480	T	G	MI.9891	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	734	245	F	C	tTc/tGc	1,31	0,98	0	probably_damaging	0,98	neutral	0,18	neutral	2,94	deleterious	-3,94	deleterious	-5,28	high_impact	4,3	neutral	0,94	neutral	0,41	deleterious	4,1	23,7	0,06	0,35	disease	0,78	disease	0,72	disease	0,69	disease	0,68	4	deleterious	0,99	neutral	0,1	deleterious	2	deleterious	0,76	low_impact	-2,31	medium_impact	-0,14	high_impact	2,71	0,14	0,8	21,58	15,99	N	0,52	P	0,78	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15480	15480	T	A	MI.9892	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	734	245	F	Y	tTc/tAc	1,31	0,98	0	benign	0,03	neutral	1	neutral	2,96	neutral	-2,69	neutral	-2,03	medium_impact	2,9	neutral	0,97	neutral	0,57	deleterious	4,2	23,9	0,21	0,45	neutral	0,28	disease	0,51	neutral	0,46	neutral	0,42	2	neutral	0,03	deleterious	0,99	neutral	-3	neutral	0,18	medium_impact	0,68	high_impact	1,85	medium_impact	1,44	0,55	0,8	21,58	15,99	N	0,41	N	0,71	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15480	15480	T	C	MI.9893	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	734	245	F	S	tTc/tCc	1,31	0,98	0	possibly_damaging	0,83	neutral	0,43	neutral	2,96	neutral	-2,62	deleterious	-5,38	high_impact	3,79	neutral	0,96	neutral	0,49	deleterious	4,31	24	0,05	0,35	disease	0,62	disease	0,7	disease	0,66	disease	0,65	3	neutral	0,82	neutral	0,3	deleterious	1	deleterious	0,71	low_impact	-1,37	medium_impact	0,16	high_impact	2,25	0,22	0,8	21,58	15,99	N	0,5	N	0,91	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15481	15481	C	G	MI.9894	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	735	245	F	L	ttC/ttG	4,52	0,99	0	benign	0,02	neutral	0,79	neutral	3,13	neutral	-0,33	deleterious	-3,39	low_impact	1,48	neutral	0,96	neutral	0,58	deleterious	3,06	22,4	0,25	0,45	neutral	0,4	disease	0,5	neutral	0,37	neutral	0,39	2	neutral	0,17	deleterious	0,89	neutral	-6	neutral	0,17	medium_impact	0,85	medium_impact	0,53	medium_impact	0,15	0,66	0,8	21,58	15,99	N	0,43	N	0,08	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15481	15481	C	A	MI.9895	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	735	245	F	L	ttC/ttA	4,52	0,99	0	benign	0,02	neutral	0,79	neutral	3,13	neutral	-0,33	deleterious	-3,39	low_impact	1,48	neutral	0,96	neutral	0,58	deleterious	3,3	22,8	0,25	0,45	neutral	0,4	disease	0,5	neutral	0,37	neutral	0,39	2	neutral	0,17	deleterious	0,89	neutral	-6	neutral	0,17	medium_impact	0,85	medium_impact	0,53	medium_impact	0,15	0,66	0,8	21,58	15,99	N	0,42	N	0,08	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15482	15482	T	C	MI.9896	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	736	246	S	P	Tca/Cca	-3,27	0	0	possibly_damaging	0,48	neutral	0,24	neutral	3,09	neutral	-2,02	deleterious	-2,99	medium_impact	2,95	neutral	0,93	neutral	0,34	deleterious	2,29	18,1	0,09	0,35	disease	0,64	disease	0,77	neutral	0,44	disease	0,56	1	neutral	0,73	neutral	0,38	NA	0	deleterious	0,56	medium_impact	-0,7	medium_impact	-0,05	medium_impact	1,49	0,33	0,8	15,53	19,51	N	0,37	N	0,9	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15482	15482	T	A	MI.9897	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	736	246	S	T	Tca/Aca	-3,27	0	0	benign	0,06	neutral	0,42	neutral	3,15	neutral	-0,37	neutral	-1,12	neutral_impact	0,68	neutral	0,98	neutral	0,93	deleterious	0,5	7,46	0,24	0,45	neutral	0,42	neutral	0,26	neutral	0,29	neutral	0,45	1	neutral	0,54	deleterious	0,68	neutral	-6	neutral	0,14	medium_impact	0,38	medium_impact	0,15	medium_impact	-0,58	0,5	0,8	15,53	19,51	N	0,44	N	0,07	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15482	15482	T	G	MI.9898	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	736	246	S	A	Tca/Gca	-3,27	0	0	benign	0	neutral	0,54	neutral	3,17	neutral	-0,03	neutral	-1,4	low_impact	0,92	neutral	0,97	neutral	0,89	deleterious	0,46	7,1	0,29	0,45	neutral	0,24	neutral	0,23	neutral	0,44	neutral	0,42	2	neutral	0,45	deleterious	0,77	neutral	-6	neutral	0,1	high_impact	2,07	medium_impact	0,26	medium_impact	-0,36	0,41	0,8	15,53	19,51	N	0,31	N	0,06	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15483	15483	C	G	MI.9899	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	737	246	S	W	tCa/tGa	-1,44	0	0	probably_damaging	0,94	neutral	0,19	neutral	3,08	neutral	-2,87	deleterious	-3,83	medium_impact	3,29	neutral	0,95	neutral	0,41	deleterious	4,27	24	0,09	0,35	disease	0,86	disease	0,73	neutral	0,46	disease	0,62	2	neutral	0,96	neutral	0,13	deleterious	1	deleterious	0,74	low_impact	-1,85	medium_impact	-0,12	medium_impact	1,79	0,24	0,8	15,53	19,51	N	0,42	N	0,62	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8570	8570	T	A	MI.99	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	44	15	L	Q	cTa/cAa	-1,49	0	0	probably_damaging	1	neutral	0,05	neutral	4,4	deleterious	-3,7	deleterious	-4,04	medium_impact	3,13	neutral	0,81	damaging	0,2	deleterious	3,83	23,4	0,24	0,65	disease	0,82	disease	0,77	disease	0,66	disease	0,75	5	deleterious	1	neutral	0,03	deleterious	1	deleterious	0,8	low_impact	-3,6	medium_impact	-0,43	medium_impact	1,59	0,67	0,9	11,5	26,27	N	0,28	N	0,71	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8990	8990	C	G	MI.990	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	464	155	A	G	gCc/gGc	7,53	1	0	probably_damaging	0,99	deleterious	0	neutral	3,73	deleterious	-3,12	deleterious	-3,52	high_impact	3,94	damaging	0,6	neutral	0,5	deleterious	4,07	23,7	0,24	0,65	disease	0,84	disease	0,84	disease	0,64	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,65	low_impact	-1,4	high_impact	2,28	0,84	0,9	44,25	8,13	P	0,52	P	0,86	disease_causing	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15483	15483	C	T	MI.9900	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	737	246	S	L	tCa/tTa	-1,44	0	0	benign	0,42	neutral	0,72	neutral	3,11	neutral	-1,15	deleterious	-2,95	low_impact	1,12	neutral	0,96	neutral	0,61	deleterious	3,1	22,5	0,12	0,4	neutral	0,46	disease	0,62	neutral	0,44	neutral	0,46	1	neutral	0,31	deleterious	0,65	neutral	-6	deleterious	0,44	medium_impact	-0,6	medium_impact	0,44	medium_impact	-0,18	0,42	0,8	15,53	19,51	N	0,23	N	0,57	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15485	15485	C	G	MI.9901	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	739	247	P	A	Cca/Gca	-10,15	0	0	probably_damaging	1	neutral	0,53	neutral	2,47	deleterious	-3,36	deleterious	-6,31	high_impact	4,86	neutral	0,93	neutral	0,51	deleterious	2,96	22,1	0,14	0,4	disease	0,53	disease	0,57	disease	0,76	disease	0,73	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,73	low_impact	-3,53	medium_impact	0,25	high_impact	3,22	0,74	0,85	55,53	8,65	P	0,62	P	0,82	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15485	15485	C	A	MI.9902	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	739	247	P	T	Cca/Aca	-10,15	0	0	probably_damaging	1	neutral	0,42	neutral	2,43	deleterious	-4,32	deleterious	-6,31	high_impact	4,39	neutral	0,92	neutral	0,43	deleterious	3,72	23,3	0,12	0,4	disease	0,58	disease	0,72	disease	0,77	disease	0,73	5	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,75	low_impact	-3,53	medium_impact	0,15	high_impact	2,79	0,56	0,8	55,53	8,65	N	0,5	N	0,96	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15485	15485	C	T	MI.9903	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	739	247	P	S	Cca/Tca	-10,15	0	0	probably_damaging	1	neutral	0,44	neutral	2,44	deleterious	-4	deleterious	-6,31	high_impact	4,45	neutral	0,93	neutral	0,45	deleterious	3,91	23,5	0,12	0,4	disease	0,62	disease	0,73	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,22	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	0,17	high_impact	2,85	0,14	0,8	55,53	8,65	N	0,5	N	0,85	polymorphism	1	0,3	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15486	15486	C	A	MI.9904	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	740	247	P	Q	cCa/cAa	4,29	0,99	0	probably_damaging	1	neutral	0,31	neutral	2,43	deleterious	-4,31	deleterious	-6,31	high_impact	3,75	neutral	0,91	neutral	0,37	deleterious	4,12	23,8	0,1	0,4	disease	0,74	disease	0,8	disease	0,8	disease	0,75	5	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-3,53	medium_impact	0,03	high_impact	2,21	0,35	0,8	55,53	8,65	P	0,55	P	0,85	polymorphism	1	0,28	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15486	15486	C	T	MI.9905	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	740	247	P	L	cCa/cTa	4,29	0,99	0	probably_damaging	1	neutral	0,69	neutral	2,42	deleterious	-4,63	deleterious	-7,9	high_impact	4,66	neutral	0,93	neutral	0,37	deleterious	4,35	24,1	0,06	0,35	neutral	0,27	disease	0,81	disease	0,75	disease	0,72	4	deleterious	1	neutral	0,35	deleterious	2	deleterious	0,73	low_impact	-3,53	medium_impact	0,41	high_impact	3,04	0,71	0,85	55,53	8,65	N	0,53	P	1	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15486	15486	C	G	MI.9906	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	740	247	P	R	cCa/cGa	4,29	0,99	0	probably_damaging	1	neutral	0,36	neutral	2,42	deleterious	-4,51	deleterious	-7,1	high_impact	5,55	neutral	0,93	neutral	0,35	deleterious	3,59	23,2	0,05	0,35	disease	0,73	disease	0,84	disease	0,86	disease	0,79	6	deleterious	1	neutral	0,18	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,09	high_impact	3,85	0,3	0,8	55,53	8,65	P	0,67	P	0,81	polymorphism	1	0,49	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15488	15488	G	T	MI.9907	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	742	248	D	Y	Gac/Tac	-6,25	0	0	probably_damaging	1	neutral	1	neutral	3,19	neutral	1,07	deleterious	-2,55	neutral_impact	0,2	neutral	0,91	neutral	0,44	deleterious	3,86	23,5	0,09	0,35	neutral	0,32	disease	0,68	neutral	0,33	neutral	0,45	1	deleterious	1	deleterious	0,5	neutral	-2	deleterious	0,72	low_impact	-3,53	high_impact	1,85	low_impact	-1,01	0,03	0,8	18,16	11,5	N	0,18	N	0,94	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15488	15488	G	C	MI.9908	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	742	248	D	H	Gac/Cac	-6,25	0	0	probably_damaging	1	neutral	0,54	neutral	3,15	neutral	-1,13	neutral	-1,03	low_impact	1,72	neutral	0,9	neutral	0,35	deleterious	3,66	23,2	0,18	0,45	disease	0,54	disease	0,68	neutral	0,43	neutral	0,48	0	deleterious	1	neutral	0,27	neutral	-2	deleterious	0,75	low_impact	-3,53	medium_impact	0,26	medium_impact	0,37	0,31	0,8	18,16	11,5	N	0,24	N	0,66	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15488	15488	G	A	MI.9909	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	742	248	D	N	Gac/Aac	-6,25	0	0	probably_damaging	1	neutral	0,33	neutral	3,19	neutral	0,84	neutral	1,63	neutral_impact	-1,12	neutral	0,85	neutral	0,51	deleterious	2,15	17,15	0,67	0,7	neutral	0,18	neutral	0,12	neutral	0,23	neutral	0,25	5	deleterious	1	neutral	0,17	neutral	-2	deleterious	0,64	low_impact	-3,53	medium_impact	0,06	low_impact	-2,21	0,65	0,8	18,16	11,5	N	0,36	N	0,23	polymorphism	1	0	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8990	8990	C	T	MI.991	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	464	155	A	V	gCc/gTc	7,53	1	0	probably_damaging	1	neutral	0,11	neutral	3,81	neutral	-1,09	deleterious	-3,45	medium_impact	3,24	damaging	0,51	neutral	0,39	deleterious	4,54	24,3	0,35	0,65	disease	0,71	disease	0,87	disease	0,64	disease	0,71	4	deleterious	1	neutral	0,06	deleterious	1	deleterious	0,84	low_impact	-3,6	medium_impact	-0,22	medium_impact	1,68	0,61	0,9	44,25	8,13	P	0,65	P	0,75	disease_causing	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15489	15489	A	G	MI.9910	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	743	248	D	G	gAc/gGc	3,15	0,99	0	probably_damaging	1	neutral	0,33	neutral	3,15	neutral	-1,03	neutral	-1,8	medium_impact	2,81	neutral	0,88	neutral	0,47	deleterious	3,9	23,5	0,15	0,4	neutral	0,49	disease	0,7	disease	0,52	disease	0,57	1	deleterious	1	neutral	0,17	deleterious	1	deleterious	0,74	low_impact	-3,53	medium_impact	0,06	medium_impact	1,36	0,19	0,8	18,16	11,5	N	0,45	N	0,14	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15489	15489	A	C	MI.9911	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	743	248	D	A	gAc/gCc	3,15	0,99	0	probably_damaging	1	neutral	0,51	neutral	3,26	neutral	0,22	deleterious	-2,73	medium_impact	3,02	neutral	0,92	neutral	0,48	deleterious	3,44	23	0,15	0,4	neutral	0,28	disease	0,62	neutral	0,48	neutral	0,47	1	deleterious	1	neutral	0,26	deleterious	1	deleterious	0,7	low_impact	-3,53	medium_impact	0,23	medium_impact	1,55	0,2	0,8	18,16	11,5	N	0,42	N	0,75	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15489	15489	A	T	MI.9912	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	743	248	D	V	gAc/gTc	3,15	0,99	0	probably_damaging	1	neutral	0,5	neutral	3,26	neutral	0,54	deleterious	-3,35	medium_impact	3,37	neutral	0,92	neutral	0,48	deleterious	3,68	23,3	0,06	0,35	neutral	0,47	disease	0,75	neutral	0,48	disease	0,54	1	deleterious	1	neutral	0,25	deleterious	1	deleterious	0,74	low_impact	-3,53	medium_impact	0,22	medium_impact	1,87	0,07	0,8	18,16	11,5	N	0,42	N	0,93	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15490	15490	C	A	MI.9913	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	744	248	D	E	gaC/gaA	4,52	0,99	0	probably_damaging	0,99	neutral	0,28	neutral	3,19	neutral	-0,11	neutral	-1,13	medium_impact	2,42	neutral	0,9	neutral	0,45	deleterious	2,62	20,3	0,36	0,5	neutral	0,28	disease	0,65	neutral	0,4	neutral	0,47	1	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,68	low_impact	-2,59	medium_impact	0	medium_impact	1	0,5	0,8	18,16	11,5	N	0,52	P	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15490	15490	C	G	MI.9914	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	744	248	D	E	gaC/gaG	4,52	0,99	0	probably_damaging	0,99	neutral	0,28	neutral	3,19	neutral	-0,11	neutral	-1,13	medium_impact	2,42	neutral	0,9	neutral	0,45	deleterious	2,28	18,04	0,36	0,5	neutral	0,28	disease	0,65	neutral	0,4	neutral	0,47	1	deleterious	0,99	neutral	0,15	deleterious	1	deleterious	0,68	low_impact	-2,59	medium_impact	0	medium_impact	1	0,5	0,8	18,16	11,5	N	0,52	P	0,46	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15491	15491	C	G	MI.9915	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	745	249	L	V	Ctc/Gtc	0,63	0,17	0	probably_damaging	0,95	neutral	0,5	neutral	3,14	neutral	-0,67	neutral	-2,06	medium_impact	2,38	neutral	0,95	damaging	0,19	neutral	1,62	13,99	0,27	0,45	neutral	0,24	neutral	0,42	disease	0,52	neutral	0,44	1	neutral	0,95	neutral	0,28	deleterious	1	deleterious	0,61	low_impact	-1,92	medium_impact	0,22	medium_impact	0,97	0,31	0,8	20,79	22	N	0,32	N	0,43	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15491	15491	C	T	MI.9916	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	745	249	L	F	Ctc/Ttc	0,63	0,17	0	probably_damaging	0,99	neutral	0,71	neutral	3,1	neutral	-1,95	deleterious	-2,66	medium_impact	2,77	neutral	0,96	damaging	0,13	deleterious	3,66	23,2	0,2	0,45	disease	0,57	disease	0,54	disease	0,54	disease	0,52	0	deleterious	0,99	neutral	0,36	deleterious	1	deleterious	0,71	low_impact	-2,59	medium_impact	0,43	medium_impact	1,32	0,42	0,8	20,79	22	N	0,21	N	0,79	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15491	15491	C	A	MI.9917	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	745	249	L	I	Ctc/Atc	0,63	0,17	0	probably_damaging	0,98	neutral	0,41	neutral	3,12	neutral	-1,26	neutral	-1,34	low_impact	1,57	neutral	0,95	neutral	0,74	deleterious	2,58	19,96	0,29	0,45	neutral	0,43	neutral	0,36	neutral	0,33	neutral	0,43	1	deleterious	0,98	neutral	0,22	neutral	-2	deleterious	0,63	low_impact	-2,31	medium_impact	0,14	medium_impact	0,23	0,46	0,8	20,79	22	N	0,36	N	0,41	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15492	15492	T	C	MI.9918	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	746	249	L	P	cTc/cCc	-1,67	0	0	probably_damaging	1	neutral	0,25	neutral	3,29	neutral	1,24	deleterious	-5,16	medium_impact	3,4	neutral	0,93	damaging	0,08	deleterious	3,91	23,5	0,02	0,35	disease	0,55	disease	0,76	disease	0,75	disease	0,74	5	deleterious	1	neutral	0,13	deleterious	1	deleterious	0,8	low_impact	-3,53	medium_impact	-0,04	medium_impact	1,89	0,18	0,8	20,79	22	N	0,37	N	0,93	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15492	15492	T	A	MI.9919	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	746	249	L	H	cTc/cAc	-1,67	0	0	probably_damaging	1	neutral	0,52	neutral	3,11	neutral	-1,73	deleterious	-5,01	high_impact	4,29	neutral	0,92	damaging	0,11	deleterious	4,13	23,8	0,05	0,35	disease	0,55	disease	0,75	disease	0,65	disease	0,67	3	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	0,24	high_impact	2,7	0,18	0,8	20,79	22	N	0,34	N	0,88	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8990	8990	C	A	MI.992	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	464	155	A	D	gCc/gAc	7,53	1	0	probably_damaging	1	deleterious	0	neutral	3,73	deleterious	-3,64	deleterious	-5,18	high_impact	3,94	neutral	0,61	neutral	0,4	deleterious	4,72	24,6	0,13	0,65	disease	0,93	disease	0,94	disease	0,74	disease	0,83	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,89	low_impact	-3,6	low_impact	-1,4	high_impact	2,28	0,72	0,9	44,25	8,13	P	0,54	P	0,99	disease_causing	1	0,31	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15492	15492	T	G	MI.9920	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	746	249	L	R	cTc/cGc	-1,67	0	0	probably_damaging	1	neutral	0,34	neutral	3,15	neutral	-0,38	deleterious	-4,41	high_impact	4,44	neutral	0,94	damaging	0,08	deleterious	4,11	23,7	0,03	0,35	disease	0,65	disease	0,85	disease	0,7	disease	0,73	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,07	high_impact	2,84	0,15	0,8	20,79	22	N	0,44	N	1	polymorphism	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15494	15494	C	G	MI.9921	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	748	250	L	V	Cta/Gta	-11,06	0	0	probably_damaging	0,95	neutral	0,58	neutral	3,03	neutral	-1,52	neutral	-2,32	high_impact	3,79	neutral	0,96	damaging	0,11	neutral	1,67	14,24	0,28	0,45	disease	0,71	neutral	0,48	disease	0,63	disease	0,61	2	neutral	0,95	neutral	0,32	deleterious	2	deleterious	0,72	low_impact	-1,92	medium_impact	0,3	high_impact	2,25	0,42	0,8	55,26	8,47	N	0,26	N	0,88	polymorphism	1	0,04	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15494	15494	C	A	MI.9922	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	748	250	L	M	Cta/Ata	-11,06	0	0	probably_damaging	1	neutral	0,27	neutral	2,98	neutral	-2,96	neutral	-1,54	high_impact	4,06	neutral	0,94	damaging	0,13	deleterious	3,54	23,1	0,26	0,45	disease	0,72	neutral	0,49	disease	0,58	disease	0,57	1	deleterious	1	neutral	0,14	deleterious	2	deleterious	0,73	low_impact	-3,53	medium_impact	-0,01	high_impact	2,49	0,53	0,8	55,26	8,47	N	0,38	N	0,94	polymorphism	1	0,05	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15495	15495	T	A	MI.9923	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	749	250	L	Q	cTa/cAa	-1,44	0	0	probably_damaging	1	neutral	0,5	neutral	3,04	deleterious	-3,31	deleterious	-4,66	high_impact	5,38	neutral	0,93	damaging	0,07	deleterious	3,97	23,6	0,03	0,35	disease	0,94	disease	0,76	disease	0,71	disease	0,8	6	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,84	low_impact	-3,53	medium_impact	0,22	high_impact	3,69	0,31	0,8	55,26	8,47	P	0,67	P	0,99	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15495	15495	T	G	MI.9924	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	749	250	L	R	cTa/cGa	-1,44	0	0	probably_damaging	1	neutral	0,52	neutral	3	deleterious	-3,87	deleterious	-4,66	high_impact	4,49	neutral	0,94	damaging	0,06	deleterious	4,07	23,7	0,02	0,35	disease	0,95	disease	0,84	disease	0,82	disease	0,84	7	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,24	high_impact	2,88	0,14	0,8	55,26	8,47	N	0,52	P	0,99	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15495	15495	T	C	MI.9925	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	749	250	L	P	cTa/cCa	-1,44	0	0	probably_damaging	1	neutral	0,32	neutral	3,01	deleterious	-3,33	deleterious	-5,45	high_impact	4,83	neutral	0,93	damaging	0,06	deleterious	3,9	23,5	0,02	0,35	disease	0,96	disease	0,72	disease	0,71	disease	0,8	6	deleterious	1	neutral	0,16	deleterious	2	deleterious	0,88	low_impact	-3,53	medium_impact	0,05	high_impact	3,19	0,24	0,8	55,26	8,47	P	0,63	P	0,99	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15497	15497	G	C	MI.9926	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	751	251	G	R	Ggc/Cgc	0,17	0,98	0,08	probably_damaging	0,94	neutral	0,42	neutral	3,09	deleterious	-3,18	deleterious	-5,28	high_impact	4,54	neutral	0,79	damaging	0,22	deleterious	3,9	23,5	0,07	0,35	disease	0,55	disease	0,88	disease	0,76	disease	0,76	5	neutral	0,94	neutral	0,24	deleterious	2	deleterious	0,77	low_impact	-1,85	medium_impact	0,15	high_impact	2,93	0,65	0,8	25,79	37,83	N	0,53	P	0,84	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15497	15497	G	A	MI.9927	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	751	251	G	S	Ggc/Agc	0,17	0,98	0,08	benign	0,13	neutral	0,51	neutral	3,13	neutral	-2,31	deleterious	-3,62	low_impact	1,64	neutral	0,89	neutral	0,56	deleterious	4,07	23,7	0,18	0,45	neutral	0,4	disease	0,74	neutral	0,48	neutral	0,47	1	neutral	0,4	deleterious	0,69	neutral	-6	neutral	0,22	medium_impact	0,04	medium_impact	0,23	medium_impact	0,3	0,65	0,8	25,79	37,83	N	0,47	N	0,09	polymorphism	1	0,08	rs199951903	other	Obesity	RCV000022894.2	MedGen:OMIM:Orphanet:SNOMED_CT	.	.	CPD	4,75	G15497A	EXIT/Obesity	+	-	Reported	4
chrM	15497	15497	G	T	MI.9928	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	751	251	G	C	Ggc/Tgc	0,17	0,98	0,08	probably_damaging	0,96	neutral	0,18	neutral	3,05	deleterious	-4,53	deleterious	-6,01	high_impact	4	neutral	0,79	damaging	0,21	deleterious	4,15	23,8	0,06	0,35	disease	0,88	disease	0,88	disease	0,65	disease	0,76	5	neutral	0,98	neutral	0,11	deleterious	2	deleterious	0,81	low_impact	-2,02	medium_impact	-0,14	high_impact	2,44	0,12	0,8	25,79	37,83	N	0,38	N	0,72	polymorphism	1	0,33	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15498	15498	G	C	MI.9929	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	752	251	G	A	gGc/gCc	4,98	1	0	benign	0,23	neutral	0,62	neutral	3,12	neutral	-1,46	deleterious	-3,83	medium_impact	3,36	neutral	0,7	neutral	0,41	deleterious	3,03	22,3	0,22	0,45	neutral	0,48	disease	0,65	disease	0,62	disease	0,55	1	neutral	0,27	deleterious	0,7	neutral	-3	neutral	0,38	medium_impact	-0,24	medium_impact	0,34	medium_impact	1,86	0,35	0,8	25,79	37,83	N	0,48	N	0,64	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8992	8992	C	G	MI.993	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	466	156	L	V	Ctg/Gtg	-9,36	0	0	probably_damaging	0,99	deleterious	0	neutral	2,31	deleterious	-5,46	deleterious	-2,58	high_impact	4,63	damaging	0,31	neutral	0,48	deleterious	3,54	23,1	0,3	0,65	disease	0,77	disease	0,64	disease	0,76	disease	0,76	5	deleterious	1	neutral	0,01	deleterious	6	deleterious	0,82	low_impact	-2,65	low_impact	-1,4	high_impact	2,87	0,75	0,9	50	8,71	P	0,72	P	0,87	disease_causing	0,83	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15498	15498	G	A	MI.9930	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	752	251	G	D	gGc/gAc	4,98	1	0	possibly_damaging	0,75	neutral	0,3	neutral	3,12	deleterious	-3,79	deleterious	-4,57	high_impact	5,09	damaging	0,44	neutral	0,3	deleterious	3,86	23,5	0,06	0,35	neutral	0,48	disease	0,86	disease	0,77	disease	0,73	5	neutral	0,8	neutral	0,28	deleterious	1	deleterious	0,69	low_impact	-1,18	medium_impact	0,02	high_impact	3,43	0,15	0,8	25,79	37,83	P	0,8	P	0,71	disease_causing_automatic	0	0,19	rs207460003	Pathogenic	Infantile_histiocytoid_cardiomyopathy	RCV000010322.2	MedGen:OMIM:Orphanet	.	.	.	.	G15498A	HiCM/WPW,DEAF	-	+	Reported	6
chrM	15498	15498	G	T	MI.9931	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	752	251	G	V	gGc/gTc	4,98	1	0	probably_damaging	0,94	neutral	0,54	neutral	3,14	neutral	-1,73	deleterious	-5,99	medium_impact	3,25	neutral	0,79	neutral	0,36	deleterious	3,76	23,3	0,07	0,35	disease	0,63	disease	0,83	disease	0,73	disease	0,73	5	neutral	0,93	neutral	0,3	deleterious	1	deleterious	0,76	low_impact	-1,85	medium_impact	0,26	medium_impact	1,76	0,1	0,8	25,79	37,83	N	0,4	N	0,86	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15500	15500	G	T	MI.9932	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	754	252	D	Y	Gac/Tac	-0,52	0,04	0	probably_damaging	1	neutral	1	neutral	3,07	deleterious	-4,49	deleterious	-6,99	high_impact	4,85	neutral	0,91	neutral	0,44	deleterious	4,01	23,6	0,04	0,35	disease	0,79	disease	0,9	disease	0,84	disease	0,8	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,84	low_impact	-3,53	high_impact	1,85	high_impact	3,21	0,07	0,8	58,16	8,73	P	0,63	P	1	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15500	15500	G	C	MI.9933	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	754	252	D	H	Gac/Cac	-0,52	0,04	0	probably_damaging	1	neutral	0,53	neutral	3,09	neutral	-1,86	deleterious	-5,43	medium_impact	2,75	neutral	0,9	neutral	0,35	deleterious	3,67	23,3	0,12	0,4	neutral	0,25	disease	0,85	disease	0,81	disease	0,73	5	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,75	low_impact	-3,53	medium_impact	0,25	medium_impact	1,3	0,23	0,8	58,16	8,73	N	0,33	N	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15500	15500	G	A	MI.9934	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	754	252	D	N	Gac/Aac	-0,52	0,04	0	probably_damaging	0,99	neutral	0,33	neutral	3,12	neutral	-2,22	deleterious	-3,87	high_impact	4,25	neutral	0,8	neutral	0,47	deleterious	2,71	20,9	0,5	0,6	neutral	0,37	disease	0,83	disease	0,78	disease	0,73	5	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,75	low_impact	-2,59	medium_impact	0,06	high_impact	2,67	0,73	0,85	58,16	8,73	N	0,49	N	0,99	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15501	15501	A	C	MI.9935	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	755	252	D	A	gAc/gCc	4,98	1	0	probably_damaging	1	neutral	0,52	neutral	3,17	neutral	-2,54	deleterious	-6,2	high_impact	4,08	neutral	0,91	neutral	0,48	deleterious	2,64	20,5	0,09	0,35	neutral	0,48	disease	0,8	disease	0,81	disease	0,73	5	deleterious	0,99	neutral	0,26	deleterious	2	deleterious	0,76	low_impact	-3,53	medium_impact	0,24	high_impact	2,51	0,26	0,8	58,16	8,73	P	0,57	P	0,95	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15501	15501	A	T	MI.9936	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	755	252	D	V	gAc/gTc	4,98	1	0	probably_damaging	1	neutral	0,5	neutral	3,09	deleterious	-4,51	deleterious	-6,99	high_impact	5,4	neutral	0,91	neutral	0,48	deleterious	4,29	24	0,04	0,35	disease	0,68	disease	0,88	disease	0,81	disease	0,77	5	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,22	high_impact	3,71	0,02	0,8	58,16	8,73	P	0,72	P	1	polymorphism	1	0,41	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15501	15501	A	G	MI.9937	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	755	252	D	G	gAc/gGc	4,98	1	0	probably_damaging	1	neutral	0,37	neutral	3,29	neutral	-1,66	deleterious	-5,43	high_impact	5,05	neutral	0,9	neutral	0,47	deleterious	4,34	24	0,09	0,35	disease	0,61	disease	0,82	disease	0,81	disease	0,74	5	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	0,1	high_impact	3,39	0,17	0,8	58,16	8,73	P	0,73	P	1	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15502	15502	C	G	MI.9938	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	756	252	D	E	gaC/gaG	6,81	1	0	probably_damaging	0,96	neutral	0,29	neutral	3,21	neutral	-1,69	deleterious	-3,1	medium_impact	2,94	neutral	0,84	neutral	0,45	deleterious	2,12	16,99	0,33	0,5	neutral	0,33	disease	0,76	disease	0,63	disease	0,66	3	neutral	0,96	neutral	0,17	deleterious	1	deleterious	0,71	low_impact	-2,02	medium_impact	0,01	medium_impact	1,48	0,51	0,8	58,16	8,73	N	0,52	P	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15502	15502	C	A	MI.9939	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	756	252	D	E	gaC/gaA	6,81	1	0	probably_damaging	0,96	neutral	0,29	neutral	3,21	neutral	-1,69	deleterious	-3,1	medium_impact	2,94	neutral	0,84	neutral	0,45	deleterious	2,45	19,11	0,33	0,5	neutral	0,33	disease	0,76	disease	0,63	disease	0,66	3	neutral	0,96	neutral	0,17	deleterious	1	deleterious	0,71	low_impact	-2,02	medium_impact	0,01	medium_impact	1,48	0,51	0,8	58,16	8,73	N	0,52	P	1	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8992	8992	C	A	MI.994	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	466	156	L	M	Ctg/Atg	-9,36	0	0	probably_damaging	1	deleterious	0	neutral	2,31	deleterious	-5,52	neutral	-1,72	high_impact	4,63	damaging	0,46	neutral	0,62	deleterious	3,9	23,5	0,24	0,65	disease	0,88	disease	0,64	disease	0,75	disease	0,77	5	deleterious	1	neutral	0	deleterious	6	deleterious	0,81	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,6	0,9	50	8,71	P	0,58	P	0,96	disease_causing	0,8	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15503	15503	C	G	MI.9940	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	757	253	P	A	Cca/Gca	0,17	0,98	0	probably_damaging	0,99	neutral	0,83	neutral	2,9	neutral	-1,69	deleterious	-5,89	medium_impact	2,94	neutral	0,86	damaging	0,15	neutral	1,49	13,25	0,16	0,45	neutral	0,39	disease	0,6	disease	0,75	disease	0,65	3	deleterious	0,99	neutral	0,42	deleterious	1	deleterious	0,7	low_impact	-2,59	medium_impact	0,6	medium_impact	1,48	0,75	0,85	57,63	8,78	N	0,33	N	0,82	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15503	15503	C	A	MI.9941	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	757	253	P	T	Cca/Aca	0,17	0,98	0	probably_damaging	1	neutral	0,6	neutral	2,79	deleterious	-3,1	deleterious	-5,87	high_impact	3,96	neutral	0,84	damaging	0,11	deleterious	3,69	23,3	0,15	0,45	neutral	0,43	disease	0,76	disease	0,75	disease	0,67	3	deleterious	1	neutral	0,3	deleterious	2	deleterious	0,72	low_impact	-3,53	medium_impact	0,32	high_impact	2,4	0,56	0,8	57,63	8,78	N	0,36	N	0,96	polymorphism	1	0,16	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15503	15503	C	T	MI.9942	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	757	253	P	S	Cca/Tca	0,17	0,98	0	probably_damaging	1	neutral	0,82	neutral	2,81	neutral	-2,66	deleterious	-5,85	medium_impact	3,18	neutral	0,85	damaging	0,1	deleterious	3,72	23,3	0,16	0,45	neutral	0,36	disease	0,76	disease	0,75	disease	0,66	3	deleterious	1	neutral	0,41	deleterious	1	deleterious	0,72	low_impact	-3,53	medium_impact	0,58	medium_impact	1,69	0,18	0,8	57,63	8,78	N	0,32	N	0,85	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15504	15504	C	A	MI.9943	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	758	253	P	Q	cCa/cAa	4,29	1	0	probably_damaging	1	neutral	0,54	neutral	2,83	neutral	-2,24	deleterious	-5,94	high_impact	5,41	neutral	0,85	damaging	0,09	deleterious	4,16	23,8	0,12	0,4	disease	0,58	disease	0,83	disease	0,79	disease	0,75	5	deleterious	1	neutral	0,27	deleterious	2	deleterious	0,75	low_impact	-3,53	medium_impact	0,26	high_impact	3,72	0,43	0,8	57,63	8,78	P	0,66	P	0,85	polymorphism	1	0,36	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15504	15504	C	T	MI.9944	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	758	253	P	L	cCa/cTa	4,29	1	0	probably_damaging	1	neutral	0,61	neutral	2,78	deleterious	-3,21	deleterious	-7,46	high_impact	4,72	neutral	0,87	damaging	0,07	deleterious	4,43	24,2	0,09	0,4	disease	0,67	disease	0,84	disease	0,75	disease	0,75	5	deleterious	1	neutral	0,31	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	0,33	high_impact	3,09	0,54	0,8	57,63	8,78	P	0,63	P	1	polymorphism	1	0,17	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15504	15504	C	G	MI.9945	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	758	253	P	R	cCa/cGa	4,29	1	0	probably_damaging	1	neutral	0,52	neutral	2,79	deleterious	-3,16	deleterious	-6,7	high_impact	5,07	neutral	0,86	damaging	0,08	deleterious	3,63	23,2	0,06	0,35	disease	0,6	disease	0,86	disease	0,82	disease	0,77	5	deleterious	1	neutral	0,26	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	0,24	high_impact	3,41	0,34	0,8	57,63	8,78	P	0,68	P	0,81	polymorphism	1	0,34	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15506	15506	G	C	MI.9946	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	760	254	D	H	Gac/Cac	-3,27	0	0	possibly_damaging	0,76	neutral	0,56	neutral	4,49	neutral	-2,99	deleterious	-3,14	high_impact	4,17	neutral	0,8	neutral	0,34	deleterious	3,58	23,2	0,18	0,45	disease	0,65	disease	0,85	disease	0,76	disease	0,77	5	neutral	0,73	neutral	0,4	deleterious	1	deleterious	0,71	low_impact	-1,2	medium_impact	0,28	high_impact	2,59	0,35	0,8	55	8,37	N	0,33	N	1	polymorphism	1	0,35	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15506	15506	G	A	MI.9947	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	760	254	D	N	Gac/Aac	-3,27	0	0	benign	0,12	neutral	0,4	neutral	4,55	neutral	-1,99	neutral	-2,42	medium_impact	2,82	neutral	0,64	neutral	0,45	deleterious	2,55	19,8	0,62	0,65	neutral	0,49	disease	0,83	disease	0,69	disease	0,7	4	neutral	0,53	deleterious	0,64	neutral	-3	neutral	0,3	medium_impact	0,08	medium_impact	0,13	medium_impact	1,37	0,46	0,8	55	8,37	N	0,28	N	0,99	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15506	15506	G	T	MI.9948	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	760	254	D	Y	Gac/Tac	-3,27	0	0	possibly_damaging	0,84	neutral	1	neutral	4,48	neutral	-1,94	deleterious	-4,64	high_impact	4,38	neutral	0,81	neutral	0,44	deleterious	3,9	23,5	0,07	0,35	disease	0,75	disease	0,9	disease	0,76	disease	0,79	6	neutral	0,84	deleterious	0,58	deleterious	1	deleterious	0,76	low_impact	-1,4	high_impact	1,85	high_impact	2,78	0,12	0,8	55	8,37	N	0,41	N	1	polymorphism	1	0,32	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15507	15507	A	T	MI.9949	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	761	254	D	V	gAc/gTc	4,98	1	0	benign	0,35	neutral	0,52	neutral	4,51	neutral	-1,93	deleterious	-4,67	high_impact	3,62	neutral	0,81	neutral	0,48	deleterious	3,53	23,1	0,06	0,35	disease	0,62	disease	0,87	disease	0,75	disease	0,78	6	neutral	0,4	deleterious	0,59	neutral	-2	deleterious	0,51	medium_impact	-0,48	medium_impact	0,24	high_impact	2,09	0,08	0,8	55	8,37	N	0,53	P	1	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8993	8993	T	G	MI.995	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	467	156	L	R	cTg/cGg	-1,03	0	0,03	probably_damaging	1	deleterious	0	neutral	2,25	deleterious	-8,72	deleterious	-5,18	high_impact	4,63	damaging	0,06	neutral	0,42	deleterious	4,27	24	0,1	0,65	disease	0,88	disease	0,88	disease	0,84	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,91	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,48	0,9	50	8,71	P	0,95	P	0,99	disease_causing_automatic	0,58	0,42	rs199476133	Pathogenic|Pathogenic,Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic	Leigh_syndrome|Ataxia_and_polyneuropathy,_adult-onset,Leigh_syndrome|Neuropathy_ataxia_retinitis_pigmentosa_syndrome|Ataxia|not_provided|Bilateral_cleft_lip_and_palate|Camptodactyly_of_finger|Hypertelorism|Low-set_ears|Postaxial_hand_polydactyly|Premature_birth|Scrotal_hypoplasia|Wide_intermamillary_distance	RCV000010275.5|RCV000010276.4,RCV000010273.3|RCV000010274.2|RCV000191106.1|RCV000224643.1|RCV000414771.1|RCV000414771.1|RCV000414771.1|RCV000414771.1|RCV000414771.1|RCV000414771.1|RCV000414771.1|RCV000414771.1	MedGen:OMIM:Orphanet:SNOMED_CT|MedGen:OMIM,MedGen:OMIM:Orphanet:SNOMED_CT|MedGen:OMIM|Human_Phenotype_Ontology:MedGen|MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen	.	.	.	.	T8993G	NARP/Leigh Disease/MILS/other	-	+	Cfrm	81
chrM	15507	15507	A	G	MI.9950	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	761	254	D	G	gAc/gGc	4,98	1	0	benign	0,16	neutral	0,35	neutral	4,5	neutral	-2	deleterious	-3,98	high_impact	4,03	neutral	0,8	neutral	0,47	deleterious	3,61	23,2	0,12	0,4	neutral	0,42	disease	0,82	disease	0,74	disease	0,74	5	neutral	0,59	deleterious	0,6	neutral	-2	neutral	0,26	medium_impact	-0,06	medium_impact	0,08	high_impact	2,47	0,26	0,8	55	8,37	P	0,59	P	1	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15507	15507	A	C	MI.9951	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	761	254	D	A	gAc/gCc	4,98	1	0	benign	0,05	neutral	0,54	neutral	4,56	neutral	-1,53	deleterious	-3,89	high_impact	3,68	neutral	0,82	neutral	0,47	deleterious	2,01	16,25	0,14	0,4	neutral	0,43	disease	0,8	disease	0,73	disease	0,72	4	neutral	0,41	deleterious	0,75	neutral	-2	neutral	0,26	medium_impact	0,46	medium_impact	0,26	high_impact	2,15	0,29	0,8	55	8,37	N	0,54	P	0,95	polymorphism	1	0,12	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15508	15508	C	G	MI.9952	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	762	254	D	E	gaC/gaG	5,67	1	0,06	benign	0,03	neutral	0,33	neutral	4,66	neutral	0,18	neutral	-0,13	neutral_impact	0,34	neutral	0,8	neutral	0,44	deleterious	0,73	9,02	0,32	0,5	neutral	0,25	neutral	0,27	neutral	0,41	neutral	0,39	2	neutral	0,65	deleterious	0,65	neutral	-6	neutral	0,13	medium_impact	0,68	medium_impact	0,06	medium_impact	-0,89	0,43	0,8	55	8,37	P	0,57	P	1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15508	15508	C	A	MI.9953	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	762	254	D	E	gaC/gaA	5,67	1	0,06	benign	0,03	neutral	0,33	neutral	4,66	neutral	0,18	neutral	-0,13	neutral_impact	0,34	neutral	0,8	neutral	0,44	neutral	1,05	10,92	0,32	0,5	neutral	0,25	neutral	0,27	neutral	0,41	neutral	0,39	2	neutral	0,65	deleterious	0,65	neutral	-6	neutral	0,13	medium_impact	0,68	medium_impact	0,06	medium_impact	-0,89	0,43	0,8	55	8,37	P	0,57	P	1	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15509	15509	A	T	MI.9954	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	763	255	N	Y	Aat/Tat	-3,04	0	0	possibly_damaging	0,73	neutral	1	neutral	4,26	deleterious	-3,96	deleterious	-6,11	high_impact	4,74	neutral	0,83	neutral	0,31	deleterious	3,35	22,9	0,1	0,4	disease	0,7	disease	0,73	disease	0,84	disease	0,75	5	neutral	0,73	deleterious	0,64	deleterious	1	deleterious	0,7	low_impact	-1,13	high_impact	1,85	high_impact	3,11	0,15	0,8	56,84	8,67	P	0,6	P	1	polymorphism	1	0,48	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15509	15509	A	G	MI.9955	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	763	255	N	D	Aat/Gat	-3,04	0	0	benign	0	neutral	0,34	neutral	4,3	neutral	-2,56	deleterious	-3,82	high_impact	4,39	neutral	0,75	neutral	0,36	deleterious	1,9	15,61	0,55	0,6	disease	0,64	disease	0,6	disease	0,8	disease	0,74	5	neutral	0,66	deleterious	0,67	neutral	-2	neutral	0,2	high_impact	2,07	medium_impact	0,07	high_impact	2,79	0,2	0,8	56,84	8,67	N	0,5	N	0,95	polymorphism	1	0,43	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15509	15509	A	C	MI.9956	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	763	255	N	H	Aat/Cat	-3,04	0	0	possibly_damaging	0,53	neutral	0,56	neutral	4,27	deleterious	-3,9	deleterious	-3,82	high_impact	4,74	neutral	0,82	damaging	0,18	deleterious	2,66	20,6	0,37	0,5	disease	0,72	disease	0,7	disease	0,84	disease	0,75	5	neutral	0,49	deleterious	0,52	deleterious	1	deleterious	0,64	medium_impact	-0,78	medium_impact	0,28	high_impact	3,11	0,1	0,8	56,84	8,67	P	0,63	P	0,98	polymorphism	1	0,46	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15510	15510	A	C	MI.9957	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	764	255	N	T	aAt/aCt	6,81	1	0	benign	0,12	neutral	0,51	neutral	4,3	neutral	-2,91	deleterious	-4,57	high_impact	4,6	neutral	0,77	neutral	0,39	neutral	1,68	14,28	0,29	0,45	disease	0,52	disease	0,74	disease	0,82	disease	0,74	5	neutral	0,4	deleterious	0,7	neutral	-2	neutral	0,37	medium_impact	0,08	medium_impact	0,23	high_impact	2,98	0,16	0,8	56,84	8,67	P	0,64	P	0,94	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15510	15510	A	T	MI.9958	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	764	255	N	I	aAt/aTt	6,81	1	0	possibly_damaging	0,65	neutral	0,43	neutral	4,26	deleterious	-3,48	deleterious	-6,88	high_impact	4,95	neutral	0,89	neutral	0,41	deleterious	4	23,6	0,1	0,4	neutral	0,38	disease	0,76	disease	0,81	disease	0,73	5	neutral	0,66	neutral	0,39	deleterious	1	deleterious	0,61	medium_impact	-0,98	medium_impact	0,16	high_impact	3,3	0,15	0,8	56,84	8,67	P	0,68	P	1	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15510	15510	A	G	MI.9959	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	764	255	N	S	aAt/aGt	6,81	1	0	benign	0,02	neutral	0,53	neutral	4,33	neutral	-2,1	deleterious	-3,8	high_impact	4,49	neutral	0,83	neutral	0,39	neutral	1,32	12,36	0,53	0,6	disease	0,5	disease	0,68	disease	0,8	disease	0,71	4	neutral	0,45	deleterious	0,76	neutral	-2	neutral	0,25	medium_impact	0,85	medium_impact	0,25	high_impact	2,88	0,13	0,8	56,84	8,67	P	0,63	P	0,86	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8993	8993	T	A	MI.996	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	467	156	L	Q	cTg/cAg	-1,03	0	0,03	probably_damaging	1	deleterious	0	neutral	2,25	deleterious	-8,91	deleterious	-5,16	high_impact	4,63	damaging	0,36	neutral	0,48	deleterious	4,27	24	0,12	0,65	disease	0,89	disease	0,83	disease	0,76	disease	0,82	6	deleterious	1	neutral	0	deleterious	6	deleterious	0,87	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,68	0,9	50	8,71	P	0,7	P	0,98	disease_causing	0,52	0,42	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15511	15511	T	A	MI.9960	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	765	255	N	K	aaT/aaA	5,44	1	0	benign	0,15	neutral	0,44	neutral	4,36	neutral	-2,72	deleterious	-4,59	high_impact	4,74	neutral	0,9	damaging	0,28	deleterious	2,64	20,4	0,38	0,5	neutral	0,37	disease	0,73	disease	0,8	disease	0,72	4	neutral	0,48	deleterious	0,65	neutral	-2	deleterious	0,49	medium_impact	-0,03	medium_impact	0,17	high_impact	3,11	0,22	0,8	56,84	8,67	P	0,68	P	1	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15511	15511	T	G	MI.9961	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	765	255	N	K	aaT/aaG	5,44	1	0	benign	0,15	neutral	0,44	neutral	4,36	neutral	-2,72	deleterious	-4,59	high_impact	4,74	neutral	0,9	damaging	0,28	deleterious	2,4	18,83	0,38	0,5	neutral	0,37	disease	0,73	disease	0,8	disease	0,72	4	neutral	0,48	deleterious	0,65	neutral	-2	deleterious	0,49	medium_impact	-0,03	medium_impact	0,17	high_impact	3,11	0,22	0,8	56,84	8,67	P	0,67	P	1	polymorphism	1	0,38	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15512	15512	T	C	MI.9962	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	766	256	Y	H	Tat/Cat	0,17	0,98	0	probably_damaging	1	neutral	0,54	neutral	4,51	neutral	-2,57	deleterious	-3,24	medium_impact	2,64	neutral	0,75	neutral	0,34	deleterious	3,37	22,9	0,15	0,4	disease	0,72	disease	0,71	disease	0,8	disease	0,77	5	deleterious	1	neutral	0,27	deleterious	1	deleterious	0,81	low_impact	-3,53	medium_impact	0,26	medium_impact	1,2	0,13	0,8	17,37	22,23	N	0,36	N	0,93	polymorphism	1	0,27	rs879031246	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15512	15512	T	G	MI.9963	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	766	256	Y	D	Tat/Gat	0,17	0,98	0	probably_damaging	1	neutral	0,27	neutral	4,51	deleterious	-3,1	deleterious	-5,36	medium_impact	3,19	neutral	0,79	neutral	0,36	deleterious	3,74	23,3	0,04	0,35	disease	0,79	disease	0,82	disease	0,84	disease	0,82	6	deleterious	1	neutral	0,14	deleterious	1	deleterious	0,84	low_impact	-3,53	medium_impact	-0,01	medium_impact	1,7	0,07	0,8	17,37	22,23	N	0,38	N	0,97	disease_causing	1	0,22	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15512	15512	T	A	MI.9964	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	766	256	Y	N	Tat/Aat	0,17	0,98	0	probably_damaging	1	neutral	0,41	neutral	4,52	neutral	-2,68	deleterious	-5,16	medium_impact	2,5	neutral	0,83	neutral	0,44	deleterious	3,98	23,6	0,07	0,35	disease	0,71	disease	0,84	disease	0,79	disease	0,78	6	deleterious	1	neutral	0,21	deleterious	1	deleterious	0,83	low_impact	-3,53	medium_impact	0,14	medium_impact	1,08	0,11	0,8	17,37	22,23	N	0,37	N	0,96	polymorphism	1	0,19	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15513	15513	A	T	MI.9965	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	767	256	Y	F	tAt/tTt	5,67	1	0	probably_damaging	0,97	neutral	0,74	neutral	4,81	neutral	1,14	neutral	0,92	neutral_impact	-1,96	neutral	0,9	neutral	0,47	neutral	-0,51	0,21	0,31	0,45	neutral	0,27	neutral	0,1	neutral	0,45	neutral	0,22	6	neutral	0,97	neutral	0,39	neutral	-2	deleterious	0,65	low_impact	-2,14	medium_impact	0,47	low_impact	-2,97	0,47	0,8	17,37	22,23	N	0,51	P	0,43	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15513	15513	A	G	MI.9966	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	767	256	Y	C	tAt/tGt	5,67	1	0	probably_damaging	1	neutral	0,17	neutral	4,51	deleterious	-3,59	deleterious	-4,61	medium_impact	2,64	neutral	0,84	neutral	0,32	deleterious	3,53	23,1	0,04	0,35	disease	0,74	disease	0,84	disease	0,81	disease	0,78	6	deleterious	1	neutral	0,09	deleterious	1	deleterious	0,81	low_impact	-3,53	medium_impact	-0,15	medium_impact	1,2	0,07	0,8	17,37	22,23	N	0,49	N	0,96	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15513	15513	A	C	MI.9967	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	767	256	Y	S	tAt/tCt	5,67	1	0	probably_damaging	1	neutral	0,42	neutral	4,57	neutral	-1,79	deleterious	-4,57	medium_impact	1,99	neutral	0,88	neutral	0,49	deleterious	3,39	23	0,06	0,35	disease	0,54	disease	0,77	disease	0,78	disease	0,77	5	deleterious	0,99	neutral	0,21	deleterious	1	deleterious	0,79	low_impact	-3,53	medium_impact	0,15	medium_impact	0,61	0,15	0,8	17,37	22,23	N	0,5	N	0,9	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15515	15515	A	C	MI.9968	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	769	257	T	P	Acc/Ccc	-2,58	0	0	benign	0,32	neutral	0,32	neutral	4,6	neutral	-1,85	deleterious	-3,73	high_impact	3,94	neutral	0,84	neutral	0,32	deleterious	3,13	22,6	0,04	0,35	disease	0,6	disease	0,71	disease	0,54	disease	0,61	2	neutral	0,61	deleterious	0,5	neutral	-2	deleterious	0,5	medium_impact	-0,43	medium_impact	0,05	high_impact	2,38	0,4	0,8	16,84	19,36	N	0,34	N	0,93	polymorphism	1	0,14	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15515	15515	A	G	MI.9969	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	769	257	T	A	Acc/Gcc	-2,58	0	0	benign	0,02	neutral	0,53	neutral	4,66	neutral	-0,5	deleterious	-2,77	medium_impact	3,05	neutral	0,92	neutral	0,59	neutral	1,59	13,78	0,25	0,45	neutral	0,33	neutral	0,4	disease	0,56	neutral	0,43	1	neutral	0,45	deleterious	0,76	neutral	-3	neutral	0,12	medium_impact	0,85	medium_impact	0,25	medium_impact	1,58	0,36	0,8	16,84	19,36	N	0,27	N	0,37	polymorphism	1	0,08	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8993	8993	T	C	MI.997	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	467	156	L	P	cTg/cCg	-1,03	0	0,03	probably_damaging	1	deleterious	0	neutral	2,25	deleterious	-8,95	deleterious	-5,96	high_impact	4,63	damaging	0,05	neutral	0,51	deleterious	3,98	23,6	0,12	0,65	disease	0,93	disease	0,83	disease	0,83	disease	0,87	7	deleterious	1	neutral	0	deleterious	6	deleterious	0,9	low_impact	-3,6	low_impact	-1,4	high_impact	2,87	0,43	0,9	50	8,71	P	0,95	P	1	disease_causing_automatic	1	0,43	rs199476133	Pathogenic|Pathogenic,Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic|Pathogenic	Leigh_syndrome|Ataxia_and_polyneuropathy,_adult-onset,Leigh_syndrome|Neuropathy_ataxia_retinitis_pigmentosa_syndrome|Ataxia|not_provided|Bilateral_cleft_lip_and_palate|Camptodactyly_of_finger|Hypertelorism|Low-set_ears|Postaxial_hand_polydactyly|Premature_birth|Scrotal_hypoplasia|Wide_intermamillary_distance	RCV000010275.5|RCV000010276.4,RCV000010273.3|RCV000010274.2|RCV000191106.1|RCV000224643.1|RCV000414771.1|RCV000414771.1|RCV000414771.1|RCV000414771.1|RCV000414771.1|RCV000414771.1|RCV000414771.1|RCV000414771.1	MedGen:OMIM:Orphanet:SNOMED_CT|MedGen:OMIM,MedGen:OMIM:Orphanet:SNOMED_CT|MedGen:OMIM|Human_Phenotype_Ontology:MedGen|MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen|Human_Phenotype_Ontology:MedGen	.	.	.	.	T8993C	NARP/Leigh Disease/MILS/other	-	+	Cfrm	27
chrM	15515	15515	A	T	MI.9970	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	769	257	T	S	Acc/Tcc	-2,58	0	0	benign	0	neutral	0,43	neutral	4,66	neutral	-0,35	neutral	-1,99	low_impact	1,39	neutral	0,91	neutral	0,88	deleterious	0,28	5,47	0,3	0,45	neutral	0,35	neutral	0,33	neutral	0,36	neutral	0,4	2	neutral	0,57	deleterious	0,72	neutral	-6	neutral	0,13	high_impact	2,07	medium_impact	0,16	medium_impact	0,07	0,61	0,8	16,84	19,36	N	0,36	N	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15516	15516	C	T	MI.9971	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	770	257	T	I	aCc/aTc	4,52	0,24	0	benign	0,01	neutral	0,42	neutral	4,76	neutral	1,07	deleterious	-3,14	neutral_impact	0,08	neutral	0,95	neutral	0,97	deleterious	2,6	20,2	0,13	0,4	neutral	0,16	neutral	0,36	neutral	0,31	neutral	0,4	2	neutral	0,57	deleterious	0,71	neutral	-6	neutral	0,1	medium_impact	1,13	medium_impact	0,15	low_impact	-1,12	0,58	0,8	16,84	19,36	N	0,33	N	0,16	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15516	15516	C	A	MI.9972	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	770	257	T	N	aCc/aAc	4,52	0,24	0	benign	0,12	neutral	0,35	neutral	4,63	neutral	-1,47	deleterious	-2,82	medium_impact	2,17	neutral	0,83	neutral	0,51	deleterious	2,13	17,05	0,33	0,5	neutral	0,42	disease	0,67	neutral	0,39	neutral	0,48	0	neutral	0,59	deleterious	0,62	neutral	-3	neutral	0,23	medium_impact	0,08	medium_impact	0,08	medium_impact	0,78	0,62	0,8	16,84	19,36	N	0,35	N	0,66	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15516	15516	C	G	MI.9973	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	770	257	T	S	aCc/aGc	4,52	0,24	0	benign	0	neutral	0,43	neutral	4,66	neutral	-0,35	neutral	-1,99	low_impact	1,39	neutral	0,91	neutral	0,88	deleterious	0,61	8,24	0,3	0,45	neutral	0,35	neutral	0,33	neutral	0,36	neutral	0,4	2	neutral	0,57	deleterious	0,72	neutral	-6	neutral	0,13	high_impact	2,07	medium_impact	0,16	medium_impact	0,07	0,61	0,8	16,84	19,36	N	0,37	N	0,18	polymorphism	1	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15518	15518	C	A	MI.9974	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	772	258	L	M	Cta/Ata	-3,5	0	0,04	possibly_damaging	0,8	neutral	0,36	neutral	4,68	neutral	-0,72	neutral	0,65	neutral_impact	0,46	neutral	0,94	neutral	0,54	deleterious	3,81	23,4	0,32	0,5	neutral	0,24	neutral	0,29	neutral	0,49	neutral	0,38	2	neutral	0,82	neutral	0,28	neutral	-3	deleterious	0,54	low_impact	-1,29	medium_impact	0,09	medium_impact	-0,78	0,49	0,8	20,26	20,03	N	0,39	N	0,55	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15518	15518	C	G	MI.9975	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	772	258	L	V	Cta/Gta	-3,5	0	0,04	benign	0,4	neutral	0,68	neutral	4,69	neutral	-0,26	neutral	0,57	neutral_impact	0,46	neutral	0,94	neutral	0,75	deleterious	3,32	22,9	0,3	0,45	neutral	0,3	neutral	0,28	disease	0,6	neutral	0,41	2	neutral	0,31	deleterious	0,64	neutral	-6	neutral	0,28	medium_impact	-0,57	medium_impact	0,4	medium_impact	-0,78	0,43	0,8	20,26	20,03	N	0,25	N	0,53	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15519	15519	T	C	MI.9976	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	773	258	L	P	cTa/cCa	2,92	0,94	0	possibly_damaging	0,72	neutral	0,73	neutral	4,92	neutral	1,33	neutral	6,67	neutral_impact	0,46	neutral	0,97	neutral	0,91	neutral	1,21	11,79	0,05	0,35	neutral	0,21	neutral	0,03	neutral	0,29	neutral	0,17	7	neutral	0,66	deleterious	0,51	neutral	-3	neutral	0,39	low_impact	-1,11	medium_impact	0,46	medium_impact	-0,78	0,11	0,8	20,26	20,03	N	0,37	N	0,01	polymorphism	1	0,01	rs200913192	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15519	15519	T	A	MI.9977	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	773	258	L	Q	cTa/cAa	2,92	0,94	0	benign	0,02	neutral	0,63	neutral	4,68	neutral	-1,23	neutral	1,25	neutral_impact	0,46	neutral	0,97	neutral	0,85	deleterious	4,06	23,7	0,09	0,35	neutral	0,22	neutral	0,48	neutral	0,4	neutral	0,44	1	neutral	0,34	deleterious	0,81	neutral	-6	neutral	0,15	medium_impact	0,85	medium_impact	0,35	medium_impact	-0,78	0,14	0,8	20,26	20,03	N	0,31	N	0,54	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15519	15519	T	G	MI.9978	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	773	258	L	R	cTa/cGa	2,92	0,94	0	benign	0,25	neutral	0,55	neutral	4,66	neutral	-1,56	neutral	0,49	low_impact	0,8	neutral	0,97	neutral	0,54	deleterious	4,21	23,9	0,05	0,35	neutral	0,34	disease	0,77	disease	0,69	disease	0,69	4	neutral	0,34	deleterious	0,65	neutral	-6	neutral	0,34	medium_impact	-0,29	medium_impact	0,27	medium_impact	-0,47	0,15	0,8	20,26	20,03	N	0,29	N	0,66	polymorphism	1	0,01	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15521	15521	G	A	MI.9979	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	775	259	A	T	Gcc/Acc	-4,42	0	0	probably_damaging	1	neutral	0,49	neutral	2,49	deleterious	-5,18	deleterious	-3,01	high_impact	5,25	neutral	0,92	neutral	0,44	deleterious	4,05	23,7	0,1	0,4	disease	0,59	disease	0,81	disease	0,72	disease	0,72	4	deleterious	1	neutral	0,25	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,21	high_impact	3,57	0,78	0,85	58,42	8,68	P	0,72	P	0,79	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8995	8995	G	T	MI.998	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	469	157	A	S	Gcc/Tcc	-1,26	0	0	probably_damaging	0,99	neutral	0,39	neutral	3,91	neutral	0	neutral	-1,72	neutral_impact	0,6	neutral	0,78	neutral	0,54	deleterious	3,8	23,4	0,42	0,65	neutral	0,34	disease	0,7	neutral	0,49	disease	0,52	0	deleterious	0,99	neutral	0,2	neutral	-2	deleterious	0,77	low_impact	-2,65	medium_impact	0,18	medium_impact	-0,58	0,89	0,9	48,67	9	N	0,24	N	0,95	polymorphism	0,97	0,03	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15521	15521	G	T	MI.9980	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	775	259	A	S	Gcc/Tcc	-4,42	0	0	probably_damaging	1	neutral	0,55	neutral	2,51	deleterious	-3,91	neutral	-2,26	high_impact	3,8	neutral	0,94	neutral	0,47	deleterious	3,48	23,1	0,19	0,45	disease	0,57	disease	0,75	disease	0,7	disease	0,69	4	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,27	high_impact	2,26	0,57	0,8	58,42	8,68	N	0,27	N	0,91	polymorphism	1	0,15	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15521	15521	G	C	MI.9981	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	775	259	A	P	Gcc/Ccc	-4,42	0	0	probably_damaging	1	neutral	1	neutral	2,44	deleterious	-6,27	deleterious	-3,8	high_impact	3,6	neutral	0,93	neutral	0,29	deleterious	3,8	23,4	0,03	0,35	disease	0,79	disease	0,79	disease	0,72	disease	0,73	5	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,85	low_impact	-3,53	high_impact	1,85	high_impact	2,08	0,52	0,8	58,42	8,68	N	0,23	N	0,98	polymorphism	1	0,27	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15522	15522	C	A	MI.9982	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	776	259	A	D	gCc/gAc	5,9	1	0	probably_damaging	1	neutral	0,38	neutral	2,44	deleterious	-6,93	deleterious	-4,53	high_impact	5,25	neutral	0,93	neutral	0,39	deleterious	4,61	24,4	0,02	0,35	disease	0,71	disease	0,83	disease	0,85	disease	0,79	6	deleterious	1	neutral	0,19	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,11	high_impact	3,57	0,39	0,8	58,42	8,68	P	0,77	P	1	polymorphism	1	0,47	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15522	15522	C	T	MI.9983	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	776	259	A	V	gCc/gTc	5,9	1	0	probably_damaging	1	neutral	0,58	neutral	2,55	deleterious	-3,08	deleterious	-3,04	high_impact	3,77	neutral	0,95	neutral	0,5	deleterious	4,21	23,9	0,08	0,35	neutral	0,48	disease	0,74	disease	0,75	disease	0,73	5	deleterious	1	neutral	0,29	deleterious	2	deleterious	0,77	low_impact	-3,53	medium_impact	0,3	high_impact	2,23	0,79	0,85	58,42	8,68	P	0,59	P	0,84	polymorphism	1	0,26	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15522	15522	C	G	MI.9984	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	776	259	A	G	gCc/gGc	5,9	1	0	probably_damaging	0,99	neutral	0,32	neutral	2,46	deleterious	-3,58	deleterious	-3,01	high_impact	4,21	neutral	0,93	neutral	0,51	deleterious	2,39	18,78	0,18	0,45	disease	0,62	disease	0,61	disease	0,78	disease	0,73	5	deleterious	0,99	neutral	0,17	deleterious	2	deleterious	0,76	low_impact	-2,59	medium_impact	0,05	high_impact	2,63	0,72	0,85	58,42	8,68	P	0,67	P	0,83	polymorphism	1	0,37	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15524	15524	A	T	MI.9985	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	778	260	N	Y	Aac/Tac	-11,52	0	0,03	probably_damaging	1	neutral	1	neutral	2,4	deleterious	-5,73	deleterious	-5,95	high_impact	5,13	neutral	0,94	neutral	0,32	deleterious	3,71	23,3	0,09	0,35	disease	0,82	disease	0,79	disease	0,85	disease	0,79	6	deleterious	1	deleterious	0,5	deleterious	2	deleterious	0,83	low_impact	-3,53	high_impact	1,85	high_impact	3,46	0,15	0,8	20,53	17,87	P	0,64	P	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15524	15524	A	G	MI.9986	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	778	260	N	D	Aac/Gac	-11,52	0	0,03	probably_damaging	0,97	neutral	0,21	neutral	2,65	neutral	-1,1	deleterious	-3,57	medium_impact	2,04	neutral	0,89	neutral	0,51	deleterious	2,13	17,08	0,34	0,5	neutral	0,32	disease	0,62	disease	0,81	disease	0,64	3	neutral	0,98	neutral	0,12	deleterious	1	deleterious	0,68	low_impact	-2,14	medium_impact	-0,09	medium_impact	0,66	0,24	0,8	20,53	17,87	N	0,47	N	0,34	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15524	15524	A	C	MI.9987	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	778	260	N	H	Aac/Cac	-11,52	0	0,03	probably_damaging	1	neutral	0,55	neutral	2,41	deleterious	-4,85	deleterious	-3,71	high_impact	5,13	neutral	0,94	damaging	0,19	deleterious	2,92	21,9	0,24	0,45	disease	0,52	disease	0,72	disease	0,85	disease	0,75	5	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	0,27	high_impact	3,46	0,2	0,8	20,53	17,87	P	0,67	P	0,81	polymorphism	1	0,23	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15525	15525	A	T	MI.9988	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	779	260	N	I	aAc/aTc	5,67	1	0	probably_damaging	1	neutral	0,41	neutral	2,4	deleterious	-6,77	deleterious	-6,68	high_impact	5,13	neutral	0,94	neutral	0,41	deleterious	4,45	24,2	0,1	0,4	disease	0,79	disease	0,8	disease	0,82	disease	0,79	6	deleterious	1	neutral	0,21	deleterious	2	deleterious	0,81	low_impact	-3,53	medium_impact	0,14	high_impact	3,46	0,07	0,8	20,53	17,87	P	0,72	P	0,98	polymorphism	1	0,24	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15525	15525	A	C	MI.9989	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	779	260	N	T	aAc/aCc	5,67	1	0	probably_damaging	0,98	neutral	0,4	neutral	2,44	deleterious	-4	deleterious	-4,42	high_impact	4,09	neutral	0,94	neutral	0,4	deleterious	2,3	18,19	0,16	0,45	disease	0,58	disease	0,8	disease	0,79	disease	0,74	5	deleterious	0,98	neutral	0,21	deleterious	2	deleterious	0,78	low_impact	-2,31	medium_impact	0,13	high_impact	2,52	0,23	0,8	20,53	17,87	P	0,62	P	0,75	polymorphism	1	0,13	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	8995	8995	G	C	MI.999	MT-ATP6	V	ENSG00000198899	ENSP00000354632	ENST00000361899	ATP6_HUMAN	P00846	4508	YP_003024031.1	469	157	A	P	Gcc/Ccc	-1,26	0	0	probably_damaging	1	deleterious	0	neutral	3,61	deleterious	-3,84	deleterious	-3,6	medium_impact	2,21	neutral	0,69	neutral	0,37	deleterious	3,9	23,5	0,11	0,65	disease	0,83	disease	0,95	disease	0,71	disease	0,84	7	deleterious	1	neutral	0	deleterious	5	deleterious	0,93	low_impact	-3,6	low_impact	-1,4	medium_impact	0,8	0,8	0,9	48,67	9	N	0,25	N	0,97	polymorphism	0,81	0,17	.	.	.	.	.	.	COSM1138410	.	.	.	.	.	.	.	.
chrM	15525	15525	A	G	MI.9990	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	779	260	N	S	aAc/aGc	5,67	1	0	probably_damaging	0,92	neutral	0,41	neutral	2,48	neutral	-2,44	deleterious	-3,66	medium_impact	3,23	neutral	0,94	neutral	0,41	deleterious	1,88	15,45	0,35	0,5	disease	0,54	disease	0,72	disease	0,78	disease	0,73	5	neutral	0,92	neutral	0,25	deleterious	1	deleterious	0,76	low_impact	-1,72	medium_impact	0,14	medium_impact	1,74	0,24	0,8	20,53	17,87	N	0,58	P	0,89	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15526	15526	C	G	MI.9991	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	780	260	N	K	aaC/aaG	8,42	1	0	probably_damaging	0,99	neutral	0,3	neutral	2,46	deleterious	-3,71	deleterious	-4,44	high_impact	4,79	neutral	0,94	damaging	0,27	deleterious	3,73	23,3	0,22	0,45	disease	0,5	disease	0,75	disease	0,84	disease	0,69	4	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	0,02	high_impact	3,16	0,21	0,8	20,53	17,87	P	0,77	P	0,95	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15526	15526	C	A	MI.9992	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	780	260	N	K	aaC/aaA	8,42	1	0	probably_damaging	0,99	neutral	0,3	neutral	2,46	deleterious	-3,71	deleterious	-4,44	high_impact	4,79	neutral	0,94	damaging	0,27	deleterious	4,17	23,8	0,22	0,45	disease	0,5	disease	0,75	disease	0,84	disease	0,69	4	deleterious	0,99	neutral	0,16	deleterious	2	deleterious	0,79	low_impact	-2,59	medium_impact	0,02	high_impact	3,16	0,21	0,8	20,53	17,87	P	0,78	P	0,95	polymorphism	1	0,21	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15527	15527	C	G	MI.9993	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	781	261	P	A	Ccc/Gcc	-2,12	0	0	probably_damaging	0,98	neutral	0,53	neutral	1,45	deleterious	-6,11	deleterious	-6,03	high_impact	3,59	neutral	0,86	damaging	0,15	neutral	1,43	12,93	0,07	0,35	disease	0,56	disease	0,5	disease	0,69	disease	0,64	3	neutral	0,97	neutral	0,28	deleterious	2	deleterious	0,74	low_impact	-2,31	medium_impact	0,25	high_impact	2,07	0,66	0,8	57,11	8,62	N	0,24	N	0,84	polymorphism	1	0,07	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15527	15527	C	T	MI.9994	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	781	261	P	S	Ccc/Tcc	-2,12	0	0	probably_damaging	1	neutral	0,4	neutral	1,52	deleterious	-4,85	deleterious	-6,02	medium_impact	2,44	neutral	0,85	damaging	0,1	deleterious	3,56	23,1	0,06	0,35	disease	0,5	disease	0,71	disease	0,64	disease	0,59	2	deleterious	1	neutral	0,2	deleterious	1	deleterious	0,79	low_impact	-3,53	medium_impact	0,13	medium_impact	1,02	0,18	0,8	57,11	8,62	N	0,23	N	0,9	polymorphism	1	0,06	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15527	15527	C	A	MI.9995	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	781	261	P	T	Ccc/Acc	-2,12	0	0	probably_damaging	1	neutral	0,39	neutral	1,43	deleterious	-7,11	deleterious	-6,03	high_impact	4,26	neutral	0,84	damaging	0,11	deleterious	3,58	23,2	0,06	0,35	neutral	0,5	disease	0,78	disease	0,74	disease	0,72	4	deleterious	1	neutral	0,2	deleterious	2	deleterious	0,78	low_impact	-3,53	medium_impact	0,12	high_impact	2,67	0,41	0,8	57,11	8,62	N	0,38	N	0,96	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15528	15528	C	G	MI.9996	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	782	261	P	R	cCc/cGc	4,29	0,99	0	probably_damaging	1	neutral	0,34	neutral	1,42	deleterious	-7,58	deleterious	-6,81	high_impact	3,84	neutral	0,86	damaging	0,08	deleterious	3,67	23,2	0,03	0,35	disease	0,62	disease	0,79	disease	0,83	disease	0,76	5	deleterious	1	neutral	0,17	deleterious	2	deleterious	0,82	low_impact	-3,53	medium_impact	0,07	high_impact	2,29	0,33	0,8	57,11	8,62	N	0,51	P	0,8	polymorphism	1	0,1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15528	15528	C	T	MI.9997	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	782	261	P	L	cCc/cTc	4,29	0,99	0	probably_damaging	1	neutral	0,67	neutral	1,42	deleterious	-7,16	deleterious	-7,57	high_impact	4,46	neutral	0,87	damaging	0,07	deleterious	4,41	24,1	0,04	0,35	disease	0,72	disease	0,74	disease	0,73	disease	0,72	4	deleterious	1	neutral	0,34	deleterious	2	deleterious	0,8	low_impact	-3,53	medium_impact	0,39	high_impact	2,86	0,72	0,85	57,11	8,62	N	0,5	N	1	polymorphism	1	0,11	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15528	15528	C	A	MI.9998	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	782	261	P	H	cCc/cAc	4,29	0,99	0	probably_damaging	1	neutral	0,56	neutral	1,41	deleterious	-8,81	deleterious	-6,81	high_impact	4,82	neutral	0,83	damaging	0,09	deleterious	4,12	23,8	0,05	0,35	disease	0,8	disease	0,76	disease	0,81	disease	0,79	6	deleterious	1	neutral	0,28	deleterious	2	deleterious	0,83	low_impact	-3,53	medium_impact	0,28	high_impact	3,18	0,28	0,8	57,11	8,62	P	0,64	P	0,71	polymorphism	1	0,2	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
chrM	15530	15530	T	A	MI.9999	MT-CYB	III	ENSG00000198727	ENSP00000354554	ENST00000361789	CYB_HUMAN	P00156	4519	YP_003024038.1	784	262	L	M	Tta/Ata	-11,75	0	0,01	probably_damaging	1	neutral	0,24	neutral	2,78	neutral	-1,2	neutral	-1,28	low_impact	1,9	neutral	0,87	damaging	0,1	deleterious	3,34	22,9	0,21	0,45	neutral	0,32	neutral	0,35	neutral	0,32	neutral	0,41	2	deleterious	1	neutral	0,12	neutral	-2	deleterious	0,7	low_impact	-3,53	medium_impact	-0,05	medium_impact	0,53	0,56	0,8	58,16	8,43	N	0,34	N	0,98	polymorphism	1	0,02	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
